Cancer_type QTL_type tag_SNP LD SNP SNP_position Alleles Methylation_probe Methylation_position Probe_related_gene Beta t-stat Correlation_coefficient (r) p-value Traits TGCT cis rs11578119 0.933 rs12128140 chr1:170406363 C/T cg09767346 chr1:170501363 GORAB 0.71 5.65 0.45 1.04e-7 Male-pattern baldness; TGCT cis rs12711979 0.765 rs881852 chr2:3821508 A/G cg17052675 chr2:3827356 NA -0.4 -7.74 -0.57 2.93e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs9381040 0.537 rs9462669 chr6:41013659 C/A cg03526776 chr6:41159608 TREML2 0.26 5.01 0.41 1.86e-6 Alzheimer's disease (late onset); TGCT cis rs2836950 0.545 rs2836940 chr21:40588696 T/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT cis rs6089584 0.927 rs3787427 chr20:60579789 T/C cg06108461 chr20:60628389 TAF4 -0.58 -8.35 -0.6 1.12e-13 Body mass index; TGCT cis rs2230307 0.572 rs17122001 chr1:100628311 A/T cg24955406 chr1:100503596 HIAT1 0.73 4.96 0.41 2.25e-6 Carotid intima media thickness; TGCT cis rs3540 0.574 rs2657947 chr15:90968977 C/T cg22089800 chr15:90895588 ZNF774 -0.72 -7.7 -0.57 3.66e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7635838 0.892 rs66974661 chr3:11482729 A/G cg00170343 chr3:11313890 ATG7 0.64 6.05 0.48 1.57e-8 HDL cholesterol; TGCT cis rs35146811 0.735 rs1636975 chr7:99812089 A/G cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs929354 0.772 rs6459738 chr7:156998532 T/G cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs35934224 0.783 rs34593728 chr22:19857489 T/C cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT trans rs208520 0.690 rs12198745 chr6:66722598 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs35306767 0.669 rs2101051 chr10:1158791 G/T cg26597838 chr10:835615 NA 0.52 5.59 0.45 1.4e-7 Eosinophil percentage of granulocytes; TGCT cis rs7524258 0.903 rs4908608 chr1:7292772 T/C cg07173049 chr1:7289937 CAMTA1 0.32 5.37 0.43 3.78e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT trans rs1974653 0.672 rs9606254 chr22:20100409 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.65 -0.57 4.76e-12 Schizophrenia; TGCT cis rs2629540 0.793 rs10794180 chr10:126449306 T/A cg08799069 chr10:126477246 METTL10 -0.3 -4.49 -0.37 1.6e-5 Cocaine dependence; TGCT cis rs9303401 0.614 rs35308719 chr17:57163501 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs854765 0.547 rs4459604 chr17:17888549 A/G cg04398451 chr17:18023971 MYO15A -0.32 -5.07 -0.41 1.44e-6 Total body bone mineral density; TGCT cis rs7937682 0.921 rs4616071 chr11:111440865 C/G cg09085632 chr11:111637200 PPP2R1B 0.85 7.07 0.54 9.77e-11 Primary sclerosing cholangitis; TGCT trans rs459571 0.792 rs55923934 chr9:136888233 C/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.72 -7.8 -0.57 2.18e-12 Platelet distribution width; TGCT cis rs67073037 0.955 rs1131880 chr2:29170676 G/C cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs7772486 0.654 rs9376958 chr6:146023040 C/T cg23711669 chr6:146136114 FBXO30 -0.88 -9.69 -0.66 7.23e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs62103177 0.714 rs28691615 chr18:77612254 C/T cg05926928 chr17:57297772 GDPD1 1.06 10.16 0.67 5.19e-18 Opioid sensitivity; TGCT cis rs372883 0.564 rs13051579 chr21:30589840 C/T cg24692254 chr21:30365293 RNF160 0.52 4.92 0.4 2.66e-6 Pancreatic cancer; TGCT cis rs1805008 0.568 rs76888998 chr16:89884310 G/T cg02628002 chr16:89649608 CPNE7 0.48 5.26 0.43 6.06e-7 Skin colour saturation; TGCT cis rs868036 0.681 rs1026737 chr15:68107072 A/C cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs6540559 0.673 rs41305104 chr1:209950848 G/A cg21951975 chr1:209979733 IRF6 0.64 4.81 0.4 4.38e-6 Cleft lip with or without cleft palate; TGCT cis rs7776786 0.934 rs17349342 chr7:18815473 A/C cg13420273 chr7:18810212 HDAC9 0.25 4.58 0.38 1.1e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -8.51 -0.61 4.86e-14 Platelet count; TGCT cis rs1153858 1.000 rs1613559 chr15:45622116 A/G cg26924012 chr15:45694286 SPATA5L1 0.96 11.77 0.73 6.36e-22 Homoarginine levels; TGCT cis rs2760061 0.598 rs2796056 chr1:228122901 G/A cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs4665809 0.618 rs7579199 chr2:26266496 G/A cg22920501 chr2:26401640 FAM59B -0.72 -6.22 -0.49 7.14e-9 Gut microbiome composition (summer); TGCT cis rs514406 0.861 rs2477741 chr1:53265278 A/G cg16325326 chr1:53192061 ZYG11B -0.7 -8.51 -0.61 4.8e-14 Monocyte count; TGCT cis rs6426558 0.537 rs12139758 chr1:227260519 A/G cg10327440 chr1:227177885 CDC42BPA 0.6 7.14 0.54 6.84e-11 Neutrophil percentage of white cells; TGCT cis rs3008870 0.585 rs2815382 chr1:67515228 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.73 7.05 0.53 1.1e-10 Lymphocyte percentage of white cells; TGCT cis rs4494114 1.000 rs7547273 chr1:39372590 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.18e-9 Blood protein levels; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs4843747 0.671 rs28451517 chr16:88109127 A/C cg06915872 chr16:87998081 BANP -0.3 -4.54 -0.38 1.33e-5 Menopause (age at onset); TGCT cis rs10782582 0.569 rs2131557 chr1:76388589 A/C cg10523679 chr1:76189770 ACADM 0.5 4.47 0.37 1.72e-5 Daytime sleep phenotypes; TGCT cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.05 0.48 1.59e-8 Alzheimer's disease; TGCT cis rs10751667 0.577 rs7946461 chr11:974035 A/G cg06064525 chr11:970664 AP2A2 -0.34 -7.97 -0.58 9.04e-13 Alzheimer's disease (late onset); TGCT cis rs6545883 0.965 rs6718887 chr2:61727215 G/A cg15711740 chr2:61764176 XPO1 -0.5 -4.51 -0.38 1.46e-5 Tuberculosis; TGCT cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg06634786 chr22:41940651 POLR3H -0.89 -8.16 -0.59 3.16e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6500602 0.673 rs4786513 chr16:4576423 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 6.01 0.48 1.88e-8 Schizophrenia; TGCT cis rs593531 0.571 rs10898983 chr11:74093992 C/T cg25592907 chr11:73676012 DNAJB13 0.31 4.52 0.38 1.45e-5 Neuroticism; TGCT cis rs9611565 0.729 rs203320 chr22:41913477 T/C cg13695892 chr22:41940480 POLR3H -0.83 -8.58 -0.61 3.21e-14 Vitiligo; TGCT cis rs796364 1.000 rs11895190 chr2:200838613 A/G cg17644776 chr2:200775616 C2orf69 -0.3 -4.49 -0.37 1.59e-5 Schizophrenia; TGCT cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg04944784 chr2:26401820 FAM59B -0.78 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT cis rs1008375 0.646 rs4235387 chr4:17569327 T/G cg16339924 chr4:17578868 LAP3 0.78 6.45 0.5 2.27e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg11003573 chr3:44754125 ZNF502 -0.46 -5.34 -0.43 4.35e-7 Depressive symptoms; TGCT cis rs9302065 0.595 rs1547746 chr13:95964267 G/A cg26751094 chr13:95954534 ABCC4 -0.35 -5.66 -0.45 1.02e-7 Blood metabolite levels; TGCT cis rs2455799 0.517 rs2345742 chr3:15939832 C/T cg12172478 chr3:16357591 RFTN1 -0.33 -4.81 -0.4 4.31e-6 Mean platelet volume; TGCT cis rs9916302 0.800 rs8081220 chr17:37473157 A/C cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs7826238 0.524 rs2921055 chr8:8319342 C/A cg06636001 chr8:8085503 FLJ10661 0.79 7.34 0.55 2.4e-11 Systolic blood pressure; TGCT cis rs3806843 0.838 rs2337514 chr5:140132732 T/C cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2147959 0.766 rs35598069 chr1:228782548 C/G cg22700015 chr1:228743131 NA 0.58 5.02 0.41 1.71e-6 Adult asthma; TGCT cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.88 9.32 0.64 5.46e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs7672127 chr4:98938477 A/G cg18180107 chr4:99064573 C4orf37 0.56 5.06 0.41 1.49e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9393777 0.844 rs35909544 chr6:27163456 G/A cg10876282 chr6:28092338 ZSCAN16 0.73 4.55 0.38 1.26e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.647 rs3812909 chr15:77176200 A/T cg23625390 chr15:77176239 SCAPER -0.39 -5.04 -0.41 1.6e-6 Blood metabolite levels; TGCT cis rs6840360 0.935 rs3919716 chr4:152456387 A/G cg17479576 chr4:152424074 FAM160A1 -0.47 -4.98 -0.41 2.06e-6 Intelligence (multi-trait analysis); TGCT trans rs1973993 0.903 rs2038646 chr1:96940371 C/G cg10631902 chr5:14652156 NA 0.31 6.82 0.52 3.6e-10 Weight; TGCT cis rs6840360 1.000 rs6823002 chr4:152604467 T/G cg17479576 chr4:152424074 FAM160A1 -0.49 -5.1 -0.42 1.25e-6 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.819 rs34818688 chr21:46672416 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9911578 1.000 rs2531734 chr17:56550804 T/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.28 -0.64 7.12e-16 Intelligence (multi-trait analysis); TGCT cis rs9399135 0.935 rs11754504 chr6:135321509 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs344364 0.511 rs337286 chr16:1965719 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.46 -4.71 -0.39 6.58e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9296092 0.538 rs9461882 chr6:33520221 A/C cg13560919 chr6:33536144 NA -0.2 -4.64 -0.38 8.68e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs12950390 0.853 rs56137679 chr17:45862112 C/G cg06532163 chr17:45867833 NA 0.37 5.96 0.47 2.45e-8 IgG glycosylation; TGCT cis rs1552244 0.554 rs6768339 chr3:10006079 G/T cg00149659 chr3:10157352 C3orf10 -0.63 -4.81 -0.4 4.27e-6 Alzheimer's disease; TGCT cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg11494091 chr17:61959527 GH2 0.44 7.34 0.55 2.52e-11 Height; TGCT cis rs185694 0.947 rs202079 chr13:30879154 C/T cg07600127 chr13:30881527 KATNAL1 -0.87 -6.77 -0.52 4.55e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs12142240 0.698 rs17357621 chr1:46807697 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs2594989 0.831 rs7651790 chr3:11572610 C/T cg00170343 chr3:11313890 ATG7 -0.64 -4.77 -0.39 5.18e-6 Circulating chemerin levels; TGCT cis rs11874712 0.965 rs28694780 chr18:43665338 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs6688613 0.729 rs7545806 chr1:166938555 T/C cg07049167 chr1:166818506 POGK 0.27 5.16 0.42 9.39e-7 Refractive astigmatism; TGCT cis rs1801251 1.000 rs1947105 chr2:233721455 A/G cg08000102 chr2:233561755 GIGYF2 0.63 6.35 0.5 3.77e-9 Coronary artery disease; TGCT cis rs10883723 0.810 rs2296582 chr10:104244139 G/T cg05855489 chr10:104503620 C10orf26 -0.57 -5.09 -0.42 1.29e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs769267 0.930 rs7254927 chr19:19404786 C/G cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs2288278 0.601 rs11651168 chr17:46597193 A/G cg25032089 chr17:46643351 HOXB3 -0.42 -5.01 -0.41 1.86e-6 Hand grip strength; TGCT cis rs2760061 0.626 rs672977 chr1:228120288 A/C cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs7267979 0.932 rs446649 chr20:25467359 A/G cg16686733 chr20:25566563 NINL 0.56 5.81 0.46 4.96e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6700896 0.522 rs11208720 chr1:66159055 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9611565 0.512 rs5758465 chr22:42175314 T/C cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs73198271 0.737 rs535094 chr8:8633928 A/G cg06671706 chr8:8559999 CLDN23 -0.36 -4.68 -0.39 7.27e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg24531977 chr5:56204891 C5orf35 -0.78 -7.74 -0.57 2.95e-12 Type 2 diabetes; TGCT cis rs6831352 0.918 rs29001201 chr4:100053861 T/C cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs12042938 0.600 rs1094656 chr1:231773675 T/C cg04892437 chr1:231737901 TSNAX-DISC1 0.46 4.81 0.4 4.33e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs8141529 0.748 rs132529 chr22:29296652 A/G cg02153584 chr22:29168773 CCDC117 -0.62 -4.93 -0.4 2.58e-6 Lymphocyte counts; TGCT cis rs7772486 0.875 rs7766595 chr6:146364507 A/T cg05347473 chr6:146136440 FBXO30 0.56 5.42 0.44 2.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4460629 0.742 rs7365544 chr1:155068748 C/A cg23973274 chr1:155060172 NA -0.25 -4.64 -0.38 8.88e-6 Serum magnesium levels; TGCT cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg22166914 chr1:53195759 ZYG11B -0.39 -6.57 -0.51 1.25e-9 Monocyte count; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg12419862 chr22:24373484 LOC391322 -0.81 -8.51 -0.61 4.7e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs35146811 0.961 rs11771139 chr7:99736059 C/T cg00553149 chr7:99775558 STAG3;GPC2 0.3 4.62 0.38 9.28e-6 Coronary artery disease; TGCT cis rs28595532 0.920 rs17324968 chr4:119772316 A/G cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs733175 0.951 rs7669090 chr4:10028131 C/T cg11266682 chr4:10021025 SLC2A9 0.48 4.48 0.37 1.7e-5 Psychosis and Alzheimer's disease; TGCT cis rs2760061 0.583 rs708124 chr1:228220771 A/T cg18477163 chr1:228402036 OBSCN 0.34 6.95 0.53 1.87e-10 Diastolic blood pressure; TGCT cis rs8017423 0.605 rs3742673 chr14:90735707 C/T cg04374321 chr14:90722782 PSMC1 0.6 5.53 0.44 1.79e-7 Mortality in heart failure; TGCT cis rs782590 0.869 rs782599 chr2:55847423 C/T cg18811423 chr2:55921094 PNPT1 0.65 6.91 0.53 2.23e-10 Metabolic syndrome; TGCT cis rs7474896 0.515 rs688608 chr10:38331624 G/A cg13720705 chr10:37990370 NA -0.43 -5.47 -0.44 2.43e-7 Obesity (extreme); TGCT trans rs28735056 0.904 rs11665111 chr18:77622996 T/C cg05926928 chr17:57297772 GDPD1 0.64 6.76 0.52 4.85e-10 Schizophrenia; TGCT cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs5833486 1 rs5833486 chr2:113957180 T/TA cg27425262 chr2:113953981 PSD4;LOC440839 0.4 4.63 0.38 9.02e-6 Red blood cell count; TGCT cis rs12497850 0.805 rs6446198 chr3:49007638 T/A cg07636037 chr3:49044803 WDR6 0.96 10.52 0.69 6.9e-19 Parkinson's disease; TGCT cis rs6671200 0.915 rs34266846 chr1:95739748 G/A cg26537280 chr1:95699037 RWDD3 0.72 5.18 0.42 8.67e-7 Stearic acid (18:0) levels; TGCT cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs3764400 0.567 rs1452662 chr17:46293310 C/T cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs67072384 0.818 rs7926287 chr11:72464525 A/G cg03713592 chr11:72463424 ARAP1 -0.82 -4.47 -0.37 1.71e-5 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs597539 0.652 rs516425 chr11:68715675 G/A cg04772025 chr11:68637568 NA 0.61 6.93 0.53 2.02e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7647973 0.588 rs62262675 chr3:49673662 A/G cg03060546 chr3:49711283 APEH -0.59 -4.93 -0.41 2.54e-6 Menarche (age at onset); TGCT cis rs10779751 0.708 rs2746640 chr1:11292952 T/A cg08854313 chr1:11322531 MTOR 0.97 8.9 0.62 5.52e-15 Body mass index; TGCT cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6912958 0.781 rs7761814 chr6:88188309 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg06634786 chr22:41940651 POLR3H -0.9 -8.93 -0.63 4.7e-15 Vitiligo; TGCT cis rs28785552 0.800 rs10853855 chr19:53232293 A/G cg22067481 chr19:53234126 ZNF611 -0.5 -7.34 -0.55 2.42e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs611744 0.967 rs655722 chr8:109197541 A/T cg21045802 chr8:109455806 TTC35 0.5 4.63 0.38 9.18e-6 Dupuytren's disease; TGCT cis rs12210905 0.841 rs72839470 chr6:27309304 T/A cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs6840360 0.615 rs9996320 chr4:152610587 T/G cg17479576 chr4:152424074 FAM160A1 -0.54 -5.28 -0.43 5.69e-7 Intelligence (multi-trait analysis); TGCT cis rs753778 0.629 rs2278447 chr8:142206905 G/C cg18755752 chr8:142205143 DENND3 -0.29 -5.18 -0.42 8.69e-7 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs12497850 0.931 rs11705888 chr3:48817289 T/C cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT trans rs57221529 0.766 rs12521988 chr5:556421 C/T cg25482853 chr8:67687455 SGK3 1.2 10.16 0.67 5.25e-18 Lung disease severity in cystic fibrosis; TGCT cis rs916888 0.610 rs199529 chr17:44837217 A/C cg01570182 chr17:44337453 NA 0.98 8.73 0.62 1.41e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg07092213 chr7:1199455 ZFAND2A -0.52 -5.99 -0.47 2.08e-8 Longevity;Endometriosis; TGCT cis rs7511006 0.858 rs2294402 chr22:50654428 T/G cg16473166 chr22:50639996 SELO 0.63 6.42 0.5 2.56e-9 Obesity-related traits; TGCT cis rs736408 0.677 rs2286798 chr3:52821177 G/T cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.5 0.37 1.56e-5 Bipolar disorder; TGCT cis rs9303542 0.625 rs9905940 chr17:46614102 A/C cg25032089 chr17:46643351 HOXB3 -0.53 -5.49 -0.44 2.16e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs4788570 0.547 rs7202479 chr16:71759679 A/C cg06353428 chr16:71660113 MARVELD3 1.49 12.95 0.76 8.56e-25 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs11096990 0.593 rs35937374 chr4:39186355 C/T cg20847110 chr4:39482781 LOC401127 0.16 4.52 0.38 1.42e-5 Cognitive function; TGCT cis rs617219 0.671 rs1062326 chr5:78617534 A/C cg23514016 chr5:78407564 BHMT -0.32 -4.78 -0.39 4.85e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.64 -6.17 -0.48 8.7e-9 Bipolar disorder; TGCT cis rs1891275 0.515 rs7092745 chr10:93483820 C/T cg07889827 chr10:93443413 NA -0.32 -6.74 -0.52 5.19e-10 Intelligence (multi-trait analysis); TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg08736216 chr1:53307985 ZYG11A 0.27 5.5 0.44 2.11e-7 Monocyte count; TGCT cis rs1729951 0.546 rs835632 chr3:136676525 A/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs8050907 0.744 rs13330134 chr16:4526923 T/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs7523050 0.730 rs34254854 chr1:109419875 C/T cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs909002 1.000 rs909002 chr1:32139635 C/T cg11573219 chr1:32083031 HCRTR1 -0.38 -4.72 -0.39 6.34e-6 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg21672276 chr3:44754072 ZNF502 -0.43 -4.78 -0.39 4.89e-6 Depressive symptoms; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs9419702 0.538 rs9322837 chr10:133539229 G/A cg20568497 chr10:133558893 NA 0.43 4.65 0.39 8.41e-6 Survival in rectal cancer; TGCT cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs597539 0.552 rs6591360 chr11:68718669 G/T cg04772025 chr11:68637568 NA 0.6 6.68 0.51 7.03e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6088580 0.561 rs3761147 chr20:32996689 G/T cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs2562456 0.917 rs6511253 chr19:21678798 A/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.66 -0.39 8.05e-6 Pain; TGCT cis rs17376456 0.877 rs10066791 chr5:93350255 G/T cg25358565 chr5:93447407 FAM172A 0.93 8.63 0.61 2.46e-14 Diabetic retinopathy; TGCT cis rs910316 0.935 rs3742771 chr14:75599647 A/G cg23033748 chr14:75592666 NEK9 0.28 4.81 0.4 4.24e-6 Height; TGCT cis rs1982963 1.000 rs1982963 chr14:52509101 C/T cg10843707 chr14:52510701 NID2 -0.41 -6.53 -0.51 1.54e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9394438 0.628 rs4714080 chr6:37544618 A/G cg00985040 chr6:37553208 NA 0.25 4.98 0.41 2.1e-6 IgG glycosylation; TGCT cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg06035815 chr6:26189597 HIST1H4D 0.44 4.53 0.38 1.39e-5 Schizophrenia; TGCT cis rs9457247 1.000 rs4710147 chr6:167374239 G/A cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.05e-6 Crohn's disease; TGCT cis rs7225537 0.559 rs3744138 chr17:17045861 C/T cg26176665 chr17:16994978 MPRIP 0.25 5.87 0.47 3.65e-8 Mean platelet volume; TGCT cis rs2354432 0.607 rs72692962 chr1:146802674 C/A cg25205988 chr1:146714368 CHD1L -1.41 -5.83 -0.46 4.57e-8 Mitochondrial DNA levels; TGCT cis rs13064447 0.789 rs55976129 chr3:12762067 T/C cg20675869 chr3:12750130 NA -0.2 -4.99 -0.41 2.03e-6 Major depression and alcohol dependence; TGCT cis rs2688608 0.618 rs28553894 chr10:75489843 C/A cg19442545 chr10:75533431 FUT11 -0.37 -5.87 -0.47 3.81e-8 Inflammatory bowel disease; TGCT cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs78487399 0.808 rs17030835 chr2:43686245 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.19 -0.42 8.37e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs35883536 0.647 rs12046413 chr1:101047430 T/C cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs525592 1 rs525592 chr11:68195104 C/T cg16797656 chr11:68205561 LRP5 0.29 5.19 0.42 8.33e-7 Bone mineral density; TGCT cis rs9814567 1.000 rs1814337 chr3:134200682 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.64 -0.65 9.67e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6722750 0.818 rs12104940 chr2:64385774 A/G cg22352474 chr2:64371530 PELI1 0.68 6.45 0.5 2.27e-9 Neuroticism; TGCT cis rs1215050 0.791 rs165242 chr4:98686482 A/C cg17366294 chr4:99064904 C4orf37 -0.47 -4.68 -0.39 7.54e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11754661 1.000 rs73011397 chr6:151205678 A/G cg01354656 chr6:151411710 MTHFD1L 0.48 4.49 0.37 1.61e-5 Alzheimer's disease (late onset); TGCT cis rs896854 0.714 rs572547 chr8:95966286 A/G cg13393036 chr8:95962371 TP53INP1 0.56 6.85 0.52 3.02e-10 Type 2 diabetes; TGCT trans rs7618501 0.633 rs7621026 chr3:49975334 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.4 0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs1215050 0.791 rs6813619 chr4:98830768 C/T cg05340658 chr4:99064831 C4orf37 -0.47 -5.89 -0.47 3.41e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4689592 0.503 rs4689064 chr4:7055603 A/G cg26116260 chr4:7069785 GRPEL1 -0.87 -6.75 -0.52 4.98e-10 Monocyte percentage of white cells; TGCT cis rs250677 0.958 rs36067 chr5:148417553 T/G cg23229984 chr5:148520753 ABLIM3 0.21 4.81 0.4 4.35e-6 Breast cancer; TGCT trans rs916888 0.821 rs70600 chr17:44860021 C/T cg22968622 chr17:43663579 NA 1.23 10.98 0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs904251 0.523 rs2776871 chr6:37481759 A/G cg08126542 chr6:37504118 NA -0.44 -6.51 -0.5 1.71e-9 Cognitive performance; TGCT cis rs6912958 0.535 rs448580 chr6:88040399 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.67 6.87 0.52 2.81e-10 Monocyte percentage of white cells; TGCT cis rs9787249 0.957 rs12074147 chr1:40203722 T/C cg24920358 chr1:40204285 PPIE 0.56 10.07 0.67 8.56e-18 Blood protein levels; TGCT cis rs453301 0.624 rs2288671 chr8:8860894 T/C cg15556689 chr8:8085844 FLJ10661 0.74 6.44 0.5 2.37e-9 Joint mobility (Beighton score); TGCT cis rs9906944 0.657 rs4643373 chr17:47123423 T/C cg20966754 chr17:47091339 IGF2BP1 -0.49 -5.4 -0.44 3.3e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs453301 0.624 rs7014430 chr8:8827737 T/G cg15556689 chr8:8085844 FLJ10661 0.69 5.82 0.46 4.65e-8 Joint mobility (Beighton score); TGCT trans rs208520 0.754 rs7753158 chr6:66875633 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.61 -0.65 1.11e-16 Exhaled nitric oxide output; TGCT cis rs28595532 0.920 rs17258830 chr4:119725543 A/T cg21605333 chr4:119757512 SEC24D -1.72 -8.96 -0.63 3.99e-15 Cannabis dependence symptom count; TGCT cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg07341220 chr16:1583899 IFT140;TMEM204 -0.29 -4.51 -0.38 1.45e-5 Coronary artery disease; TGCT cis rs4332037 0.539 rs56305291 chr7:2048706 A/G cg25834613 chr7:1915315 MAD1L1 -0.49 -4.79 -0.39 4.71e-6 Bipolar disorder; TGCT cis rs9425326 0.508 rs2500105 chr1:183809103 G/C cg15569801 chr1:184197096 NA -0.14 -5.03 -0.41 1.7e-6 Antipsychotic drug-induced QTc interval change in schizophrenia; TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg02353165 chr6:42928485 GNMT 0.95 9.59 0.65 1.25e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9393692 0.645 rs6939048 chr6:26327953 G/A cg00631329 chr6:26305371 NA -0.46 -6.9 -0.53 2.32e-10 Educational attainment; TGCT cis rs270601 0.770 rs10463891 chr5:131597392 C/T cg24060327 chr5:131705240 SLC22A5 0.64 6.82 0.52 3.52e-10 Acylcarnitine levels; TGCT cis rs9393777 0.920 rs35869525 chr6:26946687 C/T cg16898833 chr6:26189333 HIST1H4D 1.28 6.15 0.48 9.89e-9 Intelligence (multi-trait analysis); TGCT cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.72 6.65 0.51 8.38e-10 Bipolar disorder; TGCT cis rs11252926 0.537 rs4554800 chr10:458477 G/T cg18196295 chr10:418757 DIP2C -0.28 -4.76 -0.39 5.28e-6 Psychosis in Alzheimer's disease; TGCT cis rs1577917 0.771 rs3812133 chr6:86354411 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.78 -0.46 5.58e-8 Response to antipsychotic treatment; TGCT cis rs9911578 0.967 rs1267542 chr17:56654690 T/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.32 -0.64 5.54e-16 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.519 rs8189561 chr12:38296178 G/A cg26384229 chr12:38710491 ALG10B 0.8 7.04 0.53 1.17e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs17473412 1.000 rs17473944 chr5:122716797 T/C cg15125798 chr5:122621645 NA -0.57 -5.13 -0.42 1.08e-6 Total body bone mineral density; TGCT cis rs7582180 0.629 rs11678148 chr2:100966950 A/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs7264396 0.561 rs6060741 chr20:34571484 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.28 4.75 0.39 5.52e-6 Total cholesterol levels; TGCT cis rs7020830 0.898 rs495863 chr9:37346955 T/C cg14294708 chr9:37120828 ZCCHC7 1.06 13.82 0.78 7.29e-27 Schizophrenia; TGCT cis rs4665809 1.000 rs6546744 chr2:26302161 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg21724239 chr8:58056113 NA 0.38 5.12 0.42 1.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs875971 0.964 rs6945019 chr7:65922458 C/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg00786635 chr1:25594202 NA 0.57 5.96 0.47 2.4e-8 Erythrocyte sedimentation rate; TGCT cis rs17376456 0.569 rs7735009 chr5:93260865 T/C cg25358565 chr5:93447407 FAM172A -0.62 -5.97 -0.47 2.33e-8 Diabetic retinopathy; TGCT cis rs7666738 0.830 rs10028505 chr4:98962310 C/A cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3087591 0.960 rs2952979 chr17:29474298 T/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.52 0.56 9.75e-12 Hip circumference; TGCT cis rs11031096 0.782 rs7130580 chr11:4169301 G/A cg18678763 chr11:4115507 RRM1 -0.47 -5.95 -0.47 2.51e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs11249608 0.548 rs7709054 chr5:178462757 C/T cg21905437 chr5:178450457 ZNF879 0.44 4.55 0.38 1.25e-5 Pubertal anthropometrics; TGCT cis rs10504229 1.000 rs59275611 chr8:58195191 G/A cg08280861 chr8:58055591 NA 0.37 4.69 0.39 7.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg22535103 chr8:58192502 C8orf71 -0.4 -5.0 -0.41 1.94e-6 Developmental language disorder (linguistic errors); TGCT cis rs1005277 0.505 rs200937 chr10:38135772 T/C cg25427524 chr10:38739819 LOC399744 -0.37 -7.41 -0.55 1.75e-11 Extrinsic epigenetic age acceleration; TGCT cis rs7044106 0.762 rs7849566 chr9:123460769 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 6.73 0.52 5.66e-10 Hip circumference adjusted for BMI; TGCT cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg10802521 chr3:52805072 NEK4 -0.71 -8.64 -0.61 2.36e-14 Electroencephalogram traits; TGCT cis rs9326248 1.000 rs7107152 chr11:117056080 C/T cg26566898 chr11:117069891 TAGLN -0.34 -5.21 -0.42 7.59e-7 Blood protein levels; TGCT cis rs7714584 1.000 rs10065172 chr5:150227998 C/T cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs7524258 0.835 rs7543228 chr1:7306538 G/C cg07173049 chr1:7289937 CAMTA1 0.29 4.66 0.39 8e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs644799 0.965 rs499076 chr11:95546341 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9894429 0.683 rs112612275 chr17:79552604 C/A cg21028142 chr17:79581711 NPLOC4 -0.3 -6.96 -0.53 1.79e-10 Eye color traits; TGCT trans rs3780486 0.505 rs10217267 chr9:33146528 T/C cg04842962 chr6:43655489 MRPS18A 0.8 8.57 0.61 3.51e-14 IgG glycosylation; TGCT cis rs7659604 0.539 rs2221628 chr4:122795361 G/A cg19748678 chr4:122722346 EXOSC9 0.89 8.79 0.62 1.02e-14 Type 2 diabetes; TGCT cis rs28595532 0.920 rs115046587 chr4:119779604 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs11677416 1.000 rs17561 chr2:113537223 C/A cg27083787 chr2:113543245 IL1A 0.17 4.46 0.37 1.85e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs7917772 0.536 rs12357172 chr10:104388549 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -4.76 -0.39 5.28e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs548181 0.736 rs543389 chr11:125464841 A/G cg03464685 chr11:125439445 EI24 1.18 8.27 0.6 1.78e-13 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg03264133 chr6:25882463 NA -0.61 -5.53 -0.44 1.79e-7 Intelligence (multi-trait analysis); TGCT cis rs76878669 0.561 rs7117630 chr11:66154777 C/T cg18002602 chr11:66138449 SLC29A2 -0.53 -6.54 -0.51 1.43e-9 Educational attainment (years of education); TGCT cis rs7364180 0.515 rs6002503 chr22:42208672 A/G cg06634786 chr22:41940651 POLR3H -0.51 -4.85 -0.4 3.57e-6 Alzheimer's disease biomarkers; TGCT cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg08219700 chr8:58056026 NA 0.3 4.64 0.38 8.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs4953076 0.573 rs7593987 chr2:44393532 C/T cg04920474 chr2:44395004 PPM1B -0.6 -6.01 -0.47 1.93e-8 Height; TGCT cis rs317865 0.748 rs73234656 chr4:16212702 G/A cg04764131 chr4:16228633 TAPT1;FLJ39653 0.79 5.25 0.43 6.38e-7 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.74 -0.52 5.34e-10 Alzheimer's disease; TGCT cis rs12541335 0.639 rs3923433 chr8:22169798 A/T cg02788857 chr8:22132959 PIWIL2 0.27 5.06 0.41 1.45e-6 Hypertriglyceridemia; TGCT cis rs2050392 0.630 rs303426 chr10:30740379 A/G cg18806716 chr10:30721971 MAP3K8 0.44 4.69 0.39 6.96e-6 Inflammatory bowel disease; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg11905131 chr22:24372483 LOC391322 0.89 10.29 0.68 2.56e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs62103177 0.608 rs4442895 chr18:77826399 C/G cg07235805 chr18:78004237 PARD6G -0.47 -4.58 -0.38 1.1e-5 Opioid sensitivity; TGCT cis rs7647973 1.000 rs6785045 chr3:49435243 G/C cg06212747 chr3:49208901 KLHDC8B -0.59 -4.72 -0.39 6.19e-6 Menarche (age at onset); TGCT cis rs17376456 0.877 rs2085960 chr5:93399934 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs10883723 0.775 rs7917158 chr10:104246471 C/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs344364 0.511 rs2982452 chr16:1949511 G/A cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs1008375 0.933 rs6449324 chr4:17694880 G/C cg18681998 chr4:17616180 MED28 0.76 7.18 0.54 5.69e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg00814883 chr7:100076585 TSC22D4 -0.83 -8.34 -0.6 1.18e-13 Platelet count; TGCT cis rs6893300 0.506 rs35320050 chr5:179131013 C/T cg14593053 chr5:179126677 CANX 0.47 5.27 0.43 5.73e-7 Resting heart rate; TGCT cis rs12765878 0.580 rs2295786 chr10:105616482 A/T cg11005552 chr10:105648138 OBFC1 -0.39 -6.07 -0.48 1.43e-8 Coronary artery disease; TGCT cis rs931608 0.640 rs4932758 chr19:22540094 G/A cg15554505 chr19:22123728 NA -0.63 -4.57 -0.38 1.18e-5 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs1218582 0.710 rs9793588 chr1:154878878 C/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.12 -0.54 7.57e-11 Prostate cancer; TGCT cis rs2439831 0.867 rs496584 chr15:43831923 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.86 6.02 0.48 1.84e-8 Lung cancer in ever smokers; TGCT cis rs9914544 0.545 rs8073436 chr17:18801841 A/G cg26378065 chr17:18585709 ZNF286B 0.51 4.59 0.38 1.09e-5 Educational attainment (years of education); TGCT cis rs8017423 0.647 rs11626821 chr14:90824945 A/G cg04374321 chr14:90722782 PSMC1 -0.55 -5.49 -0.44 2.18e-7 Mortality in heart failure; TGCT cis rs2290402 0.536 rs4690203 chr4:881228 C/T cg11315544 chr4:1222440 CTBP1 0.26 4.46 0.37 1.84e-5 Type 2 diabetes; TGCT cis rs713587 0.713 rs1982200 chr2:25205427 C/T cg01884057 chr2:25150051 NA -0.38 -7.81 -0.57 2.04e-12 Body mass index in non-asthmatics; TGCT cis rs7714584 1.000 rs11951694 chr5:150254338 G/A cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs3027009 0.881 rs12045546 chr1:159132532 A/G cg24432768 chr1:158149974 CD1D 0.53 5.01 0.41 1.85e-6 Lean body mass and age at menarche (combined); TGCT cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs13191362 0.938 rs13192618 chr6:163132822 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.88 6.98 0.53 1.57e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs911555 0.662 rs4906322 chr14:103879032 A/G cg23461800 chr14:103021989 NA -0.33 -4.46 -0.37 1.8e-5 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.61 0.38 9.76e-6 Renal cell carcinoma; TGCT cis rs7085104 0.632 rs7096475 chr10:104609676 A/G cg15744005 chr10:104629667 AS3MT -0.46 -5.8 -0.46 5.17e-8 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs11688816 0.569 rs7591708 chr2:63022050 T/C cg17519650 chr2:63277830 OTX1 -0.52 -4.49 -0.37 1.63e-5 Body mass index; TGCT cis rs40363 0.645 rs250631 chr16:3523215 G/C cg00484396 chr16:3507460 NAT15 0.43 6.5 0.5 1.74e-9 Tuberculosis; TGCT cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs2204008 0.754 rs11514074 chr12:38401128 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.82 0.4 4.12e-6 Bladder cancer; TGCT cis rs66561647 0.520 rs13260853 chr8:128911213 C/T cg11792826 chr8:129160931 MIR1208 0.23 5.15 0.42 1e-6 Hemoglobin concentration; TGCT cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs17331151 0.573 rs3755801 chr3:52865798 G/A cg12962167 chr3:53033115 SFMBT1 0.43 4.89 0.4 3.1e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs77861329 1.000 rs352149 chr3:52209530 C/A cg08692210 chr3:52188851 WDR51A 0.94 4.83 0.4 3.91e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs2228479 0.717 rs1800358 chr16:89809319 T/C cg26513180 chr16:89883248 FANCA 0.78 4.54 0.38 1.32e-5 Skin colour saturation; TGCT cis rs77106637 0.932 rs17244499 chr11:72629946 C/T cg03713592 chr11:72463424 ARAP1 -0.82 -5.51 -0.44 1.96e-7 Type 2 diabetes; TGCT cis rs892961 0.932 rs66886702 chr17:75412714 G/A cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs11190604 1.000 rs9419897 chr10:102246125 T/C cg16342193 chr10:102329863 NA -0.39 -5.17 -0.42 9.29e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2239547 0.603 rs9870898 chr3:53092375 A/G cg11645453 chr3:52864694 ITIH4 0.31 4.95 0.41 2.33e-6 Schizophrenia; TGCT cis rs7772486 0.875 rs10457795 chr6:146415665 A/G cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2806561 0.765 rs4333826 chr1:23517514 C/T cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs6860806 0.661 rs3763112 chr5:131586480 A/G cg24060327 chr5:131705240 SLC22A5 -0.56 -5.61 -0.45 1.26e-7 Breast cancer; TGCT cis rs7216064 0.636 rs62084696 chr17:66038181 C/G cg12091567 chr17:66097778 LOC651250 1.08 8.86 0.62 7.21e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6733011 0.628 rs1983352 chr2:99454227 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.46 -4.61 -0.38 9.76e-6 Bipolar disorder; TGCT cis rs57920188 0.535 rs10915659 chr1:4092949 G/A cg20703997 chr1:4087676 NA 0.48 5.7 0.46 8.27e-8 Interleukin-17 levels; TGCT cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg21951975 chr1:209979733 IRF6 0.66 5.69 0.45 8.77e-8 Cleft lip with or without cleft palate; TGCT cis rs35264875 0.808 rs921675 chr11:68869034 A/G cg02660097 chr11:68866761 NA -0.31 -4.96 -0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs9549367 0.789 rs9549708 chr13:113891887 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.52 -0.44 1.9e-7 Platelet distribution width; TGCT cis rs9302001 0.920 rs1359409 chr13:95457725 C/T cg07483244 chr13:95358924 NA 0.37 4.8 0.4 4.42e-6 Panic disorder; TGCT cis rs6565180 0.926 rs8046445 chr16:30386262 A/G cg17640201 chr16:30407289 ZNF48 -0.98 -9.41 -0.65 3.46e-16 Tonsillectomy; TGCT cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs4689388 0.853 rs4293850 chr4:6292020 A/C cg25554036 chr4:6271136 WFS1 0.54 7.5 0.56 1.05e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs929354 0.713 rs6459733 chr7:156930550 G/C cg05182265 chr7:156933206 UBE3C -0.39 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs1005224 0.853 rs6574251 chr14:76136883 C/T cg25116370 chr14:76127843 TTLL5;C14orf1 -0.56 -4.89 -0.4 3.08e-6 Large artery stroke; TGCT cis rs17384381 0.700 rs11161617 chr1:85913538 A/G cg16011679 chr1:85725395 C1orf52 0.84 7.03 0.53 1.21e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs35491210 chr4:99003364 T/C cg18180107 chr4:99064573 C4orf37 0.51 4.68 0.39 7.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg24675658 chr1:53192096 ZYG11B -0.69 -7.9 -0.58 1.31e-12 Monocyte count; TGCT cis rs7666738 0.830 rs10017201 chr4:98983561 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs17601876 0.814 rs8038715 chr15:51561120 T/A cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs9611519 1.000 rs2273085 chr22:41615376 C/T cg13695892 chr22:41940480 POLR3H -0.51 -4.71 -0.39 6.49e-6 Neuroticism; TGCT cis rs2657888 0.931 rs7301093 chr12:56933244 G/T cg23932658 chr12:57637574 STAC3 0.48 4.56 0.38 1.19e-5 Adiponectin levels; TGCT cis rs11741688 0.631 rs4444956 chr5:178325515 A/G cg08270223 chr5:178322770 ZFP2 -0.4 -5.51 -0.44 2e-7 Sleep duration; TGCT cis rs10504229 0.817 rs55891651 chr8:58167600 C/T cg21724239 chr8:58056113 NA 0.34 4.64 0.38 8.88e-6 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.520 rs1044575 chr2:99812070 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs7772486 0.817 rs2748491 chr6:146327759 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.55 0.65 1.57e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg11845111 chr2:191398756 TMEM194B 0.41 6.02 0.48 1.85e-8 Pulse pressure; TGCT cis rs9611565 0.879 rs2235845 chr22:41729294 T/G cg06634786 chr22:41940651 POLR3H -0.62 -5.93 -0.47 2.82e-8 Vitiligo; TGCT trans rs3780486 1.000 rs10813951 chr9:33128021 C/T cg04842962 chr6:43655489 MRPS18A -1.15 -11.47 -0.72 3.37e-21 IgG glycosylation; TGCT cis rs8036030 0.604 rs11852686 chr15:74715205 A/G cg10253484 chr15:75165896 SCAMP2 -0.6 -5.58 -0.45 1.45e-7 Airflow obstruction; TGCT cis rs79349575 0.783 rs59270107 chr17:47026185 A/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs2736345 0.672 rs2618473 chr8:11344127 C/T cg24861686 chr8:11418058 BLK -0.22 -4.53 -0.38 1.35e-5 Sjögren's syndrome;Systemic lupus erythematosus; TGCT cis rs6912958 0.515 rs381782 chr6:88040649 C/T cg04972856 chr6:88032051 C6orf162;GJB7 0.39 4.48 0.37 1.7e-5 Monocyte percentage of white cells; TGCT cis rs8179 0.620 rs73232029 chr7:92287283 G/C cg15732164 chr7:92237376 CDK6 -0.29 -5.1 -0.42 1.24e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs637571 0.510 rs10896052 chr11:65579600 C/A cg04055107 chr11:65626734 MUS81;CFL1 -0.67 -6.01 -0.48 1.9e-8 Eosinophil percentage of white cells; TGCT cis rs2013441 1.000 rs11870147 chr17:20216095 A/G cg18979559 chr17:20280153 CCDC144C -0.46 -4.82 -0.4 4.19e-6 Obesity-related traits; TGCT cis rs739496 0.579 rs73422318 chr12:112275973 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs17473412 1.000 rs114337292 chr5:122738201 A/C cg15125798 chr5:122621645 NA -0.6 -5.38 -0.43 3.61e-7 Total body bone mineral density; TGCT cis rs9926296 0.605 rs6500453 chr16:89858657 C/G cg04287289 chr16:89883240 FANCA 0.93 12.17 0.74 6.69e-23 Vitiligo; TGCT cis rs28595532 0.920 rs56302493 chr4:119772382 A/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs9534288 1.000 rs9534288 chr13:46605441 T/C cg15192986 chr13:46630673 CPB2 -0.51 -6.62 -0.51 9.95e-10 Blood protein levels; TGCT cis rs2404602 0.716 rs12592171 chr15:76755133 G/C cg26408565 chr15:76604113 ETFA -0.4 -5.26 -0.43 6.23e-7 Blood metabolite levels; TGCT cis rs861020 0.630 rs655713 chr1:210006438 C/T cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs6138458 1.000 rs1977540 chr20:24900290 G/T cg26195577 chr20:24973756 C20orf3 -1.2 -12.04 -0.73 1.35e-22 Blood protein levels; TGCT cis rs61332075 0.531 rs11885695 chr2:239338632 G/A cg08773314 chr2:239334832 ASB1 -0.47 -4.99 -0.41 2.02e-6 Lung function (FEV1/FVC); TGCT cis rs7666738 0.830 rs72882693 chr4:98960804 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9486719 0.948 rs12203657 chr6:96883285 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs9883204 0.817 rs11715633 chr3:123129946 G/A cg04890266 chr3:123102914 ADCY5 0.36 5.08 0.42 1.34e-6 Birth weight; TGCT cis rs4409675 0.576 rs10751725 chr1:28216191 A/C cg23691781 chr1:28212827 C1orf38 -0.26 -5.32 -0.43 4.68e-7 Corneal astigmatism; TGCT cis rs4499344 0.730 rs434020 chr19:33104070 C/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs6545883 0.894 rs12620105 chr2:61512321 A/T cg15711740 chr2:61764176 XPO1 0.56 4.78 0.39 4.81e-6 Tuberculosis; TGCT cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg03060546 chr3:49711283 APEH 0.51 4.82 0.4 4.2e-6 Menarche (age at onset); TGCT cis rs4803468 1.000 rs9304593 chr19:41942875 A/C cg09537434 chr19:41945824 ATP5SL 0.91 10.21 0.68 3.82e-18 Height; TGCT cis rs7246657 0.722 rs1564206 chr19:38040076 C/T cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs10927875 0.541 rs1763596 chr1:16343835 C/T cg22431228 chr1:16359049 CLCNKA -0.29 -6.01 -0.47 1.92e-8 Dilated cardiomyopathy; TGCT cis rs7086627 0.515 rs10887894 chr10:82209952 A/G cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs10751667 0.643 rs7396407 chr11:929374 A/T cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs3772130 0.962 rs17742508 chr3:121559895 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.65 0.39 8.49e-6 Cognitive performance; TGCT cis rs6570726 0.791 rs12208812 chr6:145900924 T/G cg05347473 chr6:146136440 FBXO30 0.54 5.12 0.42 1.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs116095464 0.558 rs56081398 chr5:247318 C/T cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT cis rs2562456 0.876 rs11085467 chr19:21751843 A/G cg25650185 chr19:21324782 ZNF431 -0.66 -5.85 -0.46 4.18e-8 Pain; TGCT cis rs9926296 0.585 rs1800337 chr16:89845194 A/G cg21285383 chr16:89894308 SPIRE2 0.47 7.48 0.56 1.18e-11 Vitiligo; TGCT cis rs9556958 0.635 rs4529985 chr13:99167120 G/C cg15168958 chr13:99100528 FARP1 0.22 4.94 0.41 2.48e-6 Educational attainment (years of education); TGCT cis rs2070488 0.804 rs1817364 chr3:38474513 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.96 0.58 9.56e-13 Electrocardiographic conduction measures; TGCT cis rs79387448 0.745 rs59126438 chr2:103165142 T/G cg09003973 chr2:102972529 NA 0.95 6.15 0.48 9.95e-9 Gut microbiota (bacterial taxa); TGCT cis rs769267 0.965 rs2965188 chr19:19522557 G/A cg03709012 chr19:19516395 GATAD2A 0.76 6.42 0.5 2.64e-9 Tonsillectomy; TGCT cis rs9902453 0.765 rs2729447 chr17:28099002 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs904251 0.523 rs2776872 chr6:37482787 C/G cg25019722 chr6:37503610 NA -0.52 -7.9 -0.58 1.28e-12 Cognitive performance; TGCT cis rs7119 0.717 rs12904348 chr15:77815738 G/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.55 -0.38 1.26e-5 Type 2 diabetes; TGCT cis rs921968 0.613 rs1344642 chr2:219555262 G/A cg02176678 chr2:219576539 TTLL4 -0.35 -4.77 -0.39 5.04e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs225245 0.755 rs6505493 chr17:34028901 A/G cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs589249 0.963 rs682330 chr1:37154795 T/G cg04012535 chr1:37176647 NA -0.32 -5.23 -0.43 6.89e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs12579753 0.917 rs11610365 chr12:82218108 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.21 -0.49 7.45e-9 Resting heart rate; TGCT cis rs7677751 1.000 rs73252946 chr4:55125992 G/A cg17187183 chr4:55093834 PDGFRA 0.52 5.24 0.43 6.61e-7 Corneal astigmatism; TGCT cis rs826838 0.616 rs7966266 chr12:38626138 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs8032315 1.000 rs8032315 chr15:91418297 A/T cg03209642 chr15:91427605 FES 0.45 4.58 0.38 1.11e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs13118159 0.836 rs2276903 chr4:1343405 A/G cg19318889 chr4:1322082 MAEA 0.2 4.74 0.39 5.72e-6 Longevity; TGCT cis rs7829975 0.560 rs56094035 chr8:8551622 G/A cg15556689 chr8:8085844 FLJ10661 -0.54 -4.61 -0.38 1e-5 Mood instability; TGCT cis rs3820928 0.934 rs60141402 chr2:227761445 A/C cg11843606 chr2:227700838 RHBDD1 -0.53 -4.68 -0.39 7.31e-6 Pulmonary function; TGCT cis rs9653442 0.675 rs7605430 chr2:100647552 C/G cg22139774 chr2:100720529 AFF3 0.4 7.17 0.54 6.04e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10986311 0.775 rs7864941 chr9:127162888 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -4.91 -0.4 2.83e-6 Vitiligo; TGCT cis rs6089584 1.000 rs6089581 chr20:60562394 G/A cg13770153 chr20:60521292 NA -0.44 -5.62 -0.45 1.21e-7 Body mass index; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg25703541 chr22:24373054 LOC391322 -0.81 -8.68 -0.61 1.84e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs921968 0.643 rs524902 chr2:219433357 A/C cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs9527 0.590 rs10883843 chr10:104947493 C/G cg04362960 chr10:104952993 NT5C2 0.65 5.59 0.45 1.36e-7 Arsenic metabolism; TGCT cis rs67478160 0.608 rs4906368 chr14:104242397 A/C cg26031613 chr14:104095156 KLC1 -0.63 -6.38 -0.5 3.18e-9 Schizophrenia; TGCT cis rs4742903 0.935 rs726203 chr9:106906437 A/G cg21169611 chr9:106856078 SMC2 0.5 4.66 0.39 8.07e-6 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs7172809 0.573 rs17470952 chr15:77700916 G/T cg22256960 chr15:77711686 NA -0.5 -4.75 -0.39 5.55e-6 Glucose homeostasis traits; TGCT cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT cis rs6964587 1.000 rs28735847 chr7:91592755 T/C cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs2404602 0.647 rs11072626 chr15:77090826 A/G cg23625390 chr15:77176239 SCAPER -0.41 -5.12 -0.42 1.14e-6 Blood metabolite levels; TGCT trans rs208520 0.526 rs2881644 chr6:66803535 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.08 16.96 0.84 4.18e-34 Exhaled nitric oxide output; TGCT cis rs919433 0.679 rs6719832 chr2:198533369 C/T cg00792783 chr2:198669748 PLCL1 -0.53 -4.78 -0.39 4.81e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs9549367 0.789 rs7999579 chr13:113879357 T/C cg00898013 chr13:113819073 PROZ -0.39 -4.78 -0.39 4.78e-6 Platelet distribution width; TGCT trans rs1864729 0.818 rs2583510 chr8:98294452 A/G cg08679828 chr8:102218111 ZNF706 -1.05 -6.92 -0.53 2.16e-10 Estradiol plasma levels (breast cancer); TGCT cis rs10986311 0.609 rs10118498 chr9:127060124 A/G cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.59 0.38 1.07e-5 Vitiligo; TGCT cis rs514406 0.505 rs6703127 chr1:53180565 C/T cg01802117 chr1:53393560 SCP2 -0.42 -4.95 -0.41 2.32e-6 Monocyte count; TGCT cis rs858239 0.539 rs2178139 chr7:23191636 A/G cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs11718455 0.767 rs6785433 chr3:43964265 A/G cg08738300 chr3:44038990 NA 0.75 5.45 0.44 2.55e-7 Coronary artery disease; TGCT cis rs36051895 0.603 rs1590804 chr9:5177573 T/C cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.2e-20 Pediatric autoimmune diseases; TGCT cis rs3820068 0.581 rs3940061 chr1:15941276 C/T cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.26e-13 Systolic blood pressure; TGCT cis rs9640161 0.673 rs11773351 chr7:150030963 T/C cg10018233 chr7:150070692 REPIN1 0.32 4.59 0.38 1.09e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs4879913 0.768 rs2297877 chr9:35604128 C/G cg18130437 chr9:35658183 CCDC107;RMRP -0.47 -4.62 -0.38 9.48e-6 Electroencephalogram traits; TGCT cis rs9911578 0.967 rs12944948 chr17:56951474 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs12701220 0.817 rs59471534 chr7:1085224 G/A cg07217954 chr7:1067459 C7orf50 -0.47 -4.6 -0.38 1.03e-5 Bronchopulmonary dysplasia; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg02953382 chr22:24373134 LOC391322 -0.73 -6.75 -0.52 4.94e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs12477438 0.520 rs720229 chr2:99704273 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.06 0.67 8.99e-18 Chronic sinus infection; TGCT cis rs10501293 0.703 rs7937137 chr11:43031342 C/T cg03447554 chr11:43094025 NA 0.44 6.29 0.49 5.05e-9 Cognitive performance; TGCT cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg12311346 chr5:56204834 C5orf35 -0.65 -6.48 -0.5 1.99e-9 Initial pursuit acceleration; TGCT cis rs9486715 1.000 rs11153085 chr6:97066355 A/T cg06623918 chr6:96969491 KIAA0776 -1.08 -13.52 -0.77 3.67e-26 Headache; TGCT cis rs6964587 1.000 rs9969198 chr7:91567492 G/T cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs478304 0.651 rs10896037 chr11:65503424 A/G cg10518572 chr11:65560635 OVOL1 -0.24 -4.68 -0.39 7.53e-6 Acne (severe); TGCT cis rs3096299 0.967 rs16965692 chr16:89471482 C/T cg06640241 chr16:89574553 SPG7 0.65 6.21 0.49 7.49e-9 Multiple myeloma (IgH translocation); TGCT cis rs7647973 1.000 rs11710434 chr3:49346130 T/C cg06212747 chr3:49208901 KLHDC8B 0.59 4.72 0.39 6.22e-6 Menarche (age at onset); TGCT cis rs7552404 1.000 rs4949674 chr1:76213715 C/A cg10523679 chr1:76189770 ACADM 0.89 9.53 0.65 1.72e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4689388 0.890 rs4342257 chr4:6290037 G/C cg00701064 chr4:6280414 WFS1 0.4 5.11 0.42 1.2e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2404602 0.583 rs3759853 chr15:76587777 C/T cg26408565 chr15:76604113 ETFA -0.45 -6.35 -0.5 3.66e-9 Blood metabolite levels; TGCT cis rs644799 0.540 rs10831419 chr11:95478037 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.65 6.26 0.49 5.81e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2439831 0.867 rs16957627 chr15:43642657 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs208520 0.690 rs12202401 chr6:66760544 A/G cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs4253772 0.591 rs6008361 chr22:46652372 A/G cg09491104 chr22:46646882 C22orf40 0.62 6.49 0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs2797160 0.547 rs9401836 chr6:125956736 T/C cg05901451 chr6:126070800 HEY2 -0.62 -5.17 -0.42 9.25e-7 Endometrial cancer; TGCT cis rs12615966 0.872 rs55688943 chr2:105374842 T/A cg16465502 chr2:105461796 NA 0.81 4.47 0.37 1.76e-5 Pancreatic cancer; TGCT cis rs1949733 0.523 rs4619877 chr4:8543235 G/A cg13073564 chr4:8508604 NA 0.5 4.94 0.41 2.46e-6 Response to antineoplastic agents; TGCT cis rs6500602 0.893 rs6500598 chr16:4470964 G/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 5.29 0.43 5.42e-7 Schizophrenia; TGCT cis rs2172802 1.000 rs11131333 chr4:62456231 T/C cg04118610 chr4:62707027 LPHN3 -0.41 -4.83 -0.4 3.92e-6 Partial epilepsies; TGCT cis rs4319547 0.585 rs7952868 chr12:122846949 A/G cg08088222 chr12:122070432 ORAI1 0.26 4.62 0.38 9.37e-6 Body mass index; TGCT cis rs2617583 0.530 rs12652860 chr5:1453772 G/T cg13982541 chr5:1466431 LPCAT1 -0.2 -4.6 -0.38 1.02e-5 Breast cancer; TGCT cis rs13064411 0.696 rs9836396 chr3:113184282 T/C cg18753928 chr3:113234510 CCDC52 -0.67 -5.46 -0.44 2.45e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9894429 0.966 rs6565601 chr17:79580173 C/T cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs17152411 0.843 rs7895425 chr10:126582653 T/C cg07906193 chr10:126599966 NA 0.42 5.13 0.42 1.08e-6 Height; TGCT cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg05785598 chr3:49045655 WDR6 0.36 4.85 0.4 3.7e-6 Menarche (age at onset); TGCT cis rs7193541 0.550 rs28607667 chr16:74476015 C/T cg01733217 chr16:74700730 RFWD3 -0.64 -6.1 -0.48 1.24e-8 Multiple myeloma; TGCT cis rs11167764 1.000 rs7730511 chr5:141480418 T/C cg08523384 chr5:141488047 NDFIP1 -0.25 -5.03 -0.41 1.71e-6 Crohn's disease; TGCT cis rs10782582 0.609 rs1159215 chr1:76317869 A/T cg03433033 chr1:76189801 ACADM -0.45 -4.57 -0.38 1.16e-5 Daytime sleep phenotypes; TGCT cis rs3793917 0.894 rs36212731 chr10:124214976 G/T cg09507567 chr10:124027408 NA 0.4 4.92 0.4 2.66e-6 Age-related macular degeneration; TGCT cis rs308403 0.568 rs13101575 chr4:123617561 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.59 5.75 0.46 6.43e-8 Blood protein levels; TGCT cis rs9902453 0.967 rs4356528 chr17:28489670 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.56 0.51 1.32e-9 Coffee consumption (cups per day); TGCT cis rs11098499 0.629 rs28369518 chr4:120271630 T/C cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.05e-7 Corneal astigmatism; TGCT cis rs1580019 0.844 rs1376290 chr7:32486922 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.9 8.65 0.61 2.27e-14 Cognitive ability; TGCT cis rs11031096 0.617 rs12288918 chr11:4191466 G/T cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7647973 0.925 rs4955421 chr3:49218888 G/A cg05785598 chr3:49045655 WDR6 0.38 4.68 0.39 7.48e-6 Menarche (age at onset); TGCT cis rs9308731 0.644 rs10189015 chr2:111918472 G/A cg04202892 chr2:111875749 ACOXL 0.55 6.46 0.5 2.1e-9 Chronic lymphocytic leukemia; TGCT trans rs6089829 0.890 rs6062775 chr20:61663650 T/C cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs4563143 0.514 rs73030738 chr19:29312328 G/A cg12756686 chr19:29218302 NA 0.66 5.13 0.42 1.09e-6 Methadone dose in opioid dependence; TGCT cis rs875971 0.660 rs62465434 chr7:66005152 A/C cg00343986 chr7:65444356 GUSB 0.23 5.16 0.42 9.66e-7 Aortic root size; TGCT cis rs270601 0.770 rs10463891 chr5:131597392 C/T cg12564285 chr5:131593104 PDLIM4 -0.39 -4.77 -0.39 5.03e-6 Acylcarnitine levels; TGCT cis rs9811920 0.603 rs2638948 chr3:99501539 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 4.66 0.39 7.99e-6 Axial length; TGCT cis rs7666738 0.830 rs28802909 chr4:99039410 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1372520 0.684 rs2619356 chr4:90750844 C/T cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs35306767 0.761 rs11253537 chr10:1010735 G/A cg20503657 chr10:835505 NA 0.57 6.33 0.49 4.06e-9 Eosinophil percentage of granulocytes; TGCT cis rs9814567 1.000 rs10804632 chr3:134294501 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3935685 0.874 rs11072662 chr15:77999436 A/G cg25212270 chr15:78015279 NA 0.26 5.63 0.45 1.16e-7 Intelligence (multi-trait analysis); TGCT cis rs7819412 0.806 rs6980856 chr8:10938260 A/G cg21775007 chr8:11205619 TDH 0.5 4.61 0.38 9.83e-6 Triglycerides; TGCT cis rs6450176 1.000 rs3776706 chr5:53304933 T/G ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs12693043 0.967 rs2358639 chr2:175372957 A/G cg11778734 chr2:175439522 WIPF1 -0.39 -4.83 -0.4 3.96e-6 Urate levels (BMI interaction); TGCT cis rs9611519 0.828 rs9611460 chr22:41418297 T/C cg03806693 chr22:41940476 POLR3H -0.7 -6.07 -0.48 1.41e-8 Neuroticism; TGCT cis rs60154123 0.764 rs1418257 chr1:210452846 G/A cg22029157 chr1:209979665 IRF6 0.68 4.7 0.39 6.88e-6 Coronary artery disease; TGCT cis rs1801251 0.778 rs2592116 chr2:233735709 G/A cg25237894 chr2:233734115 C2orf82 -0.29 -5.63 -0.45 1.14e-7 Coronary artery disease; TGCT cis rs7772486 0.790 rs6570724 chr6:146151283 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.72 0.39 6.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs2500424 chr20:25391969 C/T cg16686733 chr20:25566563 NINL -0.59 -6.0 -0.47 2.04e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9393777 0.513 rs11967852 chr6:26612870 G/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.49 -4.45 -0.37 1.9e-5 Intelligence (multi-trait analysis); TGCT cis rs425277 0.958 rs262688 chr1:2113565 T/G cg24578937 chr1:2090814 PRKCZ 0.31 7.78 0.57 2.37e-12 Height; TGCT cis rs1867631 1.000 rs1867631 chr1:67046126 C/A cg13052034 chr1:66999238 SGIP1 0.56 4.79 0.39 4.75e-6 Menopause (age at onset); TGCT cis rs4700695 0.668 rs36837 chr5:65480007 C/A cg21114390 chr5:65439923 SFRS12 -0.79 -7.23 -0.54 4.31e-11 Facial morphology (factor 19); TGCT cis rs8070740 0.898 rs4605225 chr17:5324136 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.61 0.38 9.92e-6 Menopause (age at onset); TGCT cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg04267008 chr7:1944627 MAD1L1 0.38 5.04 0.41 1.62e-6 Bipolar disorder and schizophrenia; TGCT cis rs4888262 0.526 rs4887776 chr16:74635632 A/G cg01733217 chr16:74700730 RFWD3 0.74 7.42 0.55 1.6e-11 Testicular germ cell tumor; TGCT cis rs826838 1.000 rs10506122 chr12:38699232 A/G cg13010199 chr12:38710504 ALG10B 0.67 5.42 0.44 2.94e-7 Heart rate; TGCT cis rs7216064 1.000 rs2046323 chr17:65849927 T/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6490294 0.904 rs12423061 chr12:112404895 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs3796352 1.000 rs71301814 chr3:53117663 G/A cg15956490 chr3:53032818 SFMBT1 0.56 6.25 0.49 6.01e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7959452 0.535 rs11177577 chr12:69671791 C/T cg14784868 chr12:69753453 YEATS4 0.69 7.03 0.53 1.23e-10 Blood protein levels; TGCT cis rs7923452 0.507 rs612802 chr10:30756441 G/A cg18806716 chr10:30721971 MAP3K8 -0.55 -6.7 -0.52 6.64e-10 Itch intensity from mosquito bite; TGCT cis rs2153535 0.541 rs6923558 chr6:8461467 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2677744 0.597 rs16945091 chr15:91499081 A/T cg22570213 chr15:91497863 RCCD1 0.4 4.93 0.4 2.6e-6 Attention deficit hyperactivity disorder; TGCT cis rs986417 0.818 rs4901993 chr14:61081453 G/A cg27398547 chr14:60952738 C14orf39 1.33 9.79 0.66 4e-17 Gut microbiota (bacterial taxa); TGCT cis rs4273100 0.834 rs59415593 chr17:19223224 T/G cg01534423 chr17:18965556 NA 0.92 5.96 0.47 2.42e-8 Schizophrenia; TGCT cis rs9581857 0.579 rs3759433 chr13:27997999 C/T cg22138327 chr13:27999177 GTF3A 0.84 7.14 0.54 7.01e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs587847 0.737 rs4924153 chr15:37666010 A/T cg12309653 chr15:37170454 LOC145845 -0.3 -4.44 -0.37 1.95e-5 Intraocular pressure; TGCT cis rs8014204 1.000 rs10483863 chr14:75322327 A/G cg06637938 chr14:75390232 RPS6KL1 -0.63 -5.97 -0.47 2.35e-8 Caffeine consumption; TGCT cis rs7249142 0.562 rs10854009 chr19:19284705 A/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.45 -4.5 -0.37 1.56e-5 IgG glycosylation; TGCT cis rs709400 0.663 rs11628969 chr14:103940911 G/A cg26031613 chr14:104095156 KLC1 0.85 9.72 0.66 5.87e-17 Body mass index; TGCT cis rs9858542 0.953 rs9859556 chr3:49455986 G/T cg03060546 chr3:49711283 APEH -0.62 -5.47 -0.44 2.4e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg11494091 chr17:61959527 GH2 0.61 14.07 0.78 1.86e-27 Prudent dietary pattern; TGCT cis rs9911578 0.842 rs12450766 chr17:56832965 G/C cg12560992 chr17:57184187 TRIM37 -0.72 -7.51 -0.56 1.01e-11 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.967 rs10894268 chr11:130717153 C/T cg05962950 chr11:130786565 SNX19 0.73 7.82 0.57 1.97e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7727544 0.606 rs10058074 chr5:131686146 G/A cg24060327 chr5:131705240 SLC22A5 -0.5 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs6840360 0.593 rs4696107 chr4:152606823 G/A cg22705602 chr4:152727874 NA -0.32 -5.27 -0.43 5.96e-7 Intelligence (multi-trait analysis); TGCT cis rs34467563 1.000 rs12541366 chr8:97398842 A/T cg15747595 chr8:98289880 TSPYL5 0.41 4.44 0.37 1.99e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs3749237 0.595 rs1464568 chr3:49458266 G/A cg03060546 chr3:49711283 APEH 0.75 8.62 0.61 2.66e-14 Resting heart rate; TGCT cis rs12134245 0.747 rs35654098 chr1:92001452 T/A cg25838465 chr1:92012736 NA -0.41 -6.57 -0.51 1.23e-9 Breast cancer; TGCT cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg07507251 chr3:52567010 NT5DC2 0.48 6.76 0.52 4.9e-10 Intelligence (multi-trait analysis); TGCT cis rs6074578 0.679 rs4142303 chr20:139841 A/T cg16931068 chr20:139680 DEFB127 -0.26 -4.7 -0.39 6.68e-6 Hirschsprung disease; TGCT cis rs11122272 0.766 rs2486732 chr1:231531476 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.19 -0.54 5.3e-11 Hemoglobin concentration; TGCT cis rs1953600 0.540 rs2784773 chr10:81919800 A/G cg01528321 chr10:82214614 TSPAN14 0.57 5.51 0.44 2.01e-7 Sarcoidosis; TGCT cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs208520 1.000 rs12216109 chr6:66987488 C/G cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs1577917 0.771 rs2842607 chr6:86345039 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs1008375 1.000 rs4698641 chr4:17642630 C/T cg16339924 chr4:17578868 LAP3 0.63 5.26 0.43 6.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7829975 0.517 rs12542733 chr8:8824858 G/T cg08975724 chr8:8085496 FLJ10661 -0.57 -4.98 -0.41 2.06e-6 Mood instability; TGCT cis rs4805272 0.962 rs8110833 chr19:29322794 A/G cg15000279 chr19:29285009 NA -0.52 -5.61 -0.45 1.28e-7 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs4478858 0.735 rs11576621 chr1:31795460 A/G cg00250761 chr1:31883323 NA -0.27 -4.84 -0.4 3.76e-6 Alcohol dependence; TGCT cis rs9948 0.786 rs6756482 chr2:97458561 A/G cg01990225 chr2:97406019 LMAN2L -0.76 -4.76 -0.39 5.32e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs1577917 0.958 rs11755048 chr6:86514334 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.15e-7 Response to antipsychotic treatment; TGCT cis rs13022357 1.000 rs2042497 chr2:160085788 T/C cg00168785 chr2:160142643 WDSUB1 0.46 4.6 0.38 1.04e-5 Sudden cardiac arrest; TGCT cis rs7666738 0.830 rs11097609 chr4:99011707 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs988913 1.000 rs6902422 chr6:54811210 C/T cg04690482 chr6:54711388 FAM83B -0.29 -4.44 -0.37 1.97e-5 Menarche (age at onset); TGCT cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg06481639 chr22:41940642 POLR3H -0.72 -6.52 -0.51 1.61e-9 Vitiligo; TGCT cis rs2354432 0.505 rs3737845 chr1:146724408 A/G cg25205988 chr1:146714368 CHD1L 1.35 5.95 0.47 2.5e-8 Mitochondrial DNA levels; TGCT trans rs7618501 0.633 rs9866695 chr3:50069452 G/T cg21659725 chr3:3221576 CRBN -0.75 -9.19 -0.64 1.13e-15 Intelligence (multi-trait analysis); TGCT cis rs7586879 0.521 rs1865689 chr2:25108197 C/T cg01884057 chr2:25150051 NA -0.29 -5.57 -0.45 1.51e-7 Body mass index; TGCT cis rs3751972 0.911 rs2191058 chr17:26232917 T/C cg02948944 chr17:26242737 NA 0.51 7.12 0.54 7.68e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs9611519 0.894 rs9611486 chr22:41458784 C/G cg13695892 chr22:41940480 POLR3H -0.54 -4.75 -0.39 5.56e-6 Neuroticism; TGCT cis rs10779751 1.000 rs4845986 chr1:11288633 G/C cg08854313 chr1:11322531 MTOR 0.96 10.11 0.67 6.65e-18 Body mass index; TGCT cis rs7267979 0.844 rs2424703 chr20:25270124 G/A cg14121845 chr20:25566513 NINL 0.45 4.6 0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11679640 0.543 rs10208080 chr2:43106956 A/G cg00484711 chr2:42331922 NA 0.2 4.48 0.37 1.65e-5 White matter hyperintensity burden; TGCT cis rs12477438 0.520 rs11695379 chr2:99742161 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.01 12.33 0.74 2.69e-23 Chronic sinus infection; TGCT cis rs999943 0.810 rs62407648 chr6:33622436 C/G cg14003231 chr6:33640908 ITPR3 0.4 4.92 0.4 2.69e-6 Obesity (extreme); TGCT cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg04267008 chr7:1944627 MAD1L1 -0.37 -4.98 -0.41 2.08e-6 Bipolar disorder and schizophrenia; TGCT cis rs36405 1.000 rs36404 chr14:72358082 C/A cg10066683 chr14:71515513 PCNX 0.24 4.7 0.39 6.69e-6 Yang-deficiency constitution; TGCT cis rs4372836 0.828 rs6728459 chr2:28999336 A/G cg09522027 chr2:28974177 PPP1CB -0.72 -6.02 -0.48 1.86e-8 Body mass index; TGCT cis rs1395 0.744 rs57881048 chr2:27474165 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs36051895 0.522 rs12341844 chr9:5177872 C/T cg02405213 chr9:5042618 JAK2 -0.74 -10.38 -0.68 1.47e-18 Pediatric autoimmune diseases; TGCT cis rs67311347 0.955 rs6764102 chr3:40378153 C/G cg17264618 chr3:40429014 ENTPD3 0.31 4.46 0.37 1.81e-5 Renal cell carcinoma; TGCT cis rs7611238 0.560 rs12054406 chr3:195038772 G/A cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.94e-6 Body mass index; TGCT cis rs9486719 1.000 rs11152959 chr6:96900272 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs9583531 0.891 rs9515270 chr13:111352073 C/T cg24331049 chr13:111365604 ING1 -0.71 -4.65 -0.38 8.54e-6 Coronary artery disease; TGCT cis rs3796352 1.000 rs113995589 chr3:53132372 A/T cg15956490 chr3:53032818 SFMBT1 0.54 6.37 0.5 3.42e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9611565 1.000 rs5751086 chr22:41768862 C/T cg06481639 chr22:41940642 POLR3H -0.51 -4.64 -0.38 8.64e-6 Vitiligo; TGCT cis rs1532993 0.518 rs6812613 chr4:98630198 G/A cg05340658 chr4:99064831 C4orf37 -0.4 -4.91 -0.4 2.77e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs7953249 0.656 rs2243616 chr12:121406370 G/T cg02403541 chr12:121454288 C12orf43 -0.63 -5.44 -0.44 2.7e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs1670533 1.000 rs13134921 chr4:1054177 A/G cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs9486715 0.758 rs9386528 chr6:96928514 G/A cg06623918 chr6:96969491 KIAA0776 -1.04 -11.84 -0.73 4.12e-22 Headache; TGCT cis rs8013055 0.846 rs10136015 chr14:105973469 A/C cg23356831 chr14:105996513 TMEM121 0.41 6.33 0.49 4.01e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs477895 0.878 rs7478730 chr11:64018827 C/T cg23719950 chr11:63933701 MACROD1 -0.69 -5.74 -0.46 6.94e-8 Mean platelet volume; TGCT cis rs9814567 1.000 rs11706117 chr3:134212526 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.06 -0.63 2.4e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs72720396 0.789 rs12048450 chr1:91199660 G/A cg13456504 chr1:91191583 NA 0.64 5.34 0.43 4.22e-7 Morning vs. evening chronotype;Chronotype; TGCT cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.69 -0.66 7.12e-17 Platelet count; TGCT cis rs732765 0.734 rs4899530 chr14:75165825 A/G cg06637938 chr14:75390232 RPS6KL1 -0.57 -5.0 -0.41 1.93e-6 Non-small cell lung cancer; TGCT cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg18305652 chr10:134549665 INPP5A 0.34 5.79 0.46 5.31e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7937612 1.000 rs7478880 chr11:120261791 C/T cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.5 -0.37 1.53e-5 Intraocular pressure; TGCT cis rs6860806 0.695 rs11952099 chr5:131576772 A/G cg24060327 chr5:131705240 SLC22A5 -0.58 -5.92 -0.47 2.93e-8 Breast cancer; TGCT cis rs3540 0.960 rs2238327 chr15:91012949 G/A cg22089800 chr15:90895588 ZNF774 0.74 6.91 0.53 2.27e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg26516362 chr5:178986906 RUFY1 0.44 4.91 0.4 2.84e-6 Lung cancer; TGCT cis rs9581857 0.547 rs75783371 chr13:28109961 T/C cg22138327 chr13:27999177 GTF3A 0.7 4.53 0.38 1.36e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6684514 1.000 rs12041164 chr1:156279811 G/A cg20302342 chr1:156215951 PAQR6 0.36 4.77 0.39 5.1e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs35306767 0.903 rs34270014 chr10:904666 T/C cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs9399401 0.667 rs34018047 chr6:142790873 G/C cg03128060 chr6:142623767 GPR126 0.37 4.54 0.38 1.33e-5 Chronic obstructive pulmonary disease; TGCT cis rs6545977 0.527 rs2710647 chr2:63213970 T/C cg17519650 chr2:63277830 OTX1 0.71 7.11 0.54 8.2e-11 Prostate cancer; TGCT cis rs8002180 0.959 rs9590229 chr13:95923399 C/T cg24476569 chr13:95954382 ABCC4 0.41 5.07 0.41 1.42e-6 Blood metabolite levels; TGCT cis rs4273100 0.512 rs1355128 chr17:19299144 G/A cg03910582 chr17:19030146 GRAPL -0.43 -5.78 -0.46 5.6e-8 Schizophrenia; TGCT cis rs10782582 0.593 rs6675076 chr1:76118503 A/C cg10523679 chr1:76189770 ACADM -0.68 -7.22 -0.54 4.52e-11 Daytime sleep phenotypes; TGCT cis rs523522 0.923 rs10774553 chr12:120954984 T/C cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs7666738 0.830 rs4334758 chr4:98971875 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs28465658 chr4:99035866 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs9393033 chr6:8521446 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs17293817 0.650 rs12778422 chr10:1413776 A/G cg19299265 chr10:1975631 NA 0.27 4.6 0.38 1.04e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg22920501 chr2:26401640 FAM59B 0.77 5.98 0.47 2.26e-8 Gut microbiome composition (summer); TGCT cis rs910187 0.605 rs6122559 chr20:45810617 T/G cg27589058 chr20:45804311 EYA2 -0.37 -7.96 -0.58 9.41e-13 Migraine; TGCT cis rs12497850 0.931 rs6791542 chr3:48787219 A/G cg06212747 chr3:49208901 KLHDC8B 0.62 5.75 0.46 6.47e-8 Parkinson's disease; TGCT trans rs877282 0.853 rs12763400 chr10:763617 C/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs8042680 0.554 rs6496746 chr15:91532869 C/A cg22570213 chr15:91497863 RCCD1 0.42 4.51 0.38 1.51e-5 Type 2 diabetes; TGCT cis rs6089584 0.888 rs2892060 chr20:60617955 G/T cg06108461 chr20:60628389 TAF4 -0.69 -10.77 -0.7 1.71e-19 Body mass index; TGCT cis rs12479064 0.724 rs3792143 chr2:100057020 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -6.02 -0.48 1.85e-8 Chronic sinus infection; TGCT cis rs769267 0.896 rs10405625 chr19:19579046 T/G cg03709012 chr19:19516395 GATAD2A 0.75 6.2 0.49 7.59e-9 Tonsillectomy; TGCT cis rs7552404 0.924 rs1146581 chr1:76213024 T/G cg10523679 chr1:76189770 ACADM 0.84 9.32 0.64 5.67e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs910316 0.646 rs11546525 chr14:75537381 C/T cg08847533 chr14:75593920 NEK9 0.7 6.59 0.51 1.14e-9 Height; TGCT cis rs1218582 0.510 rs2878411 chr1:154823545 C/T cg06221963 chr1:154839813 KCNN3 -0.55 -7.64 -0.57 5.13e-12 Prostate cancer; TGCT cis rs7666738 0.830 rs35752787 chr4:98935202 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3026101 0.671 rs748486 chr17:5290824 C/A cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.57 0.38 1.16e-5 Body mass index; TGCT cis rs916888 0.697 rs199516 chr17:44856485 C/T cg15921436 chr17:44337874 NA -0.51 -7.04 -0.53 1.17e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs172166 0.694 rs203877 chr6:28048624 T/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.79 0.39 4.75e-6 Cardiac Troponin-T levels; TGCT cis rs3749237 0.595 rs11130196 chr3:49490149 A/C cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg27211696 chr2:191398769 TMEM194B -0.27 -5.03 -0.41 1.71e-6 Pulse pressure; TGCT cis rs28595532 0.920 rs17258050 chr4:119672019 G/A cg21605333 chr4:119757512 SEC24D 1.33 7.24 0.55 4.06e-11 Cannabis dependence symptom count; TGCT cis rs8014204 0.566 rs12587457 chr14:75164141 C/T cg06637938 chr14:75390232 RPS6KL1 0.62 5.6 0.45 1.33e-7 Caffeine consumption; TGCT cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg20607798 chr8:58055168 NA 0.45 4.68 0.39 7.47e-6 Developmental language disorder (linguistic errors); TGCT cis rs3733585 0.638 rs17185835 chr4:9958180 T/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.68 -0.51 7.16e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs877282 0.898 rs2004478 chr10:770709 C/A cg17470449 chr10:769945 NA 0.32 4.93 0.4 2.56e-6 Uric acid levels; TGCT cis rs9911578 1.000 rs9911578 chr17:56953147 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg10150615 chr22:24372951 LOC391322 -0.76 -8.15 -0.59 3.33e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13191362 0.935 rs34141091 chr6:162953893 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.67 5.16 0.42 9.64e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg08392591 chr16:89556376 ANKRD11 0.55 5.27 0.43 5.97e-7 Multiple myeloma (IgH translocation); TGCT cis rs10214930 0.553 rs6943712 chr7:27917884 T/C cg05786569 chr7:27702416 HIBADH 0.75 5.17 0.42 9.13e-7 Hypospadias; TGCT cis rs2204008 0.837 rs12370891 chr12:37984531 A/G cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs6964587 1.000 rs2188154 chr7:91595138 T/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs42648 0.806 rs6951894 chr7:89893945 A/G cg25739043 chr7:89950458 NA -0.53 -4.71 -0.39 6.61e-6 Homocysteine levels; TGCT cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs6582630 0.555 rs10785454 chr12:38476260 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs308403 0.509 rs1849430 chr4:123674701 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.78 0.73 5.72e-22 Blood protein levels; TGCT cis rs6911131 0.730 rs12206238 chr6:143867406 C/T cg26846959 chr6:143998958 PHACTR2 0.84 4.52 0.38 1.44e-5 Response to paliperidone in schizophrenia (positive Marder score); TGCT cis rs9435341 0.896 rs1730851 chr1:107596443 A/G cg09367891 chr1:107599246 PRMT6 -0.61 -5.35 -0.43 4.09e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs950027 0.549 rs11070452 chr15:45594836 C/A cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.85 -0.46 4.14e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs7647973 0.592 rs6774202 chr3:49687779 T/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs35306767 0.953 rs11253517 chr10:970524 A/G cg20503657 chr10:835505 NA -0.65 -9.23 -0.64 9.26e-16 Eosinophil percentage of granulocytes; TGCT cis rs9560113 0.550 rs1163633 chr13:112231561 G/T cg10483660 chr13:112241077 NA -0.31 -4.94 -0.41 2.47e-6 Menarche (age at onset); TGCT cis rs79839061 0.732 rs35177456 chr4:828994 C/T cg07828340 chr4:882639 GAK 0.4 5.03 0.41 1.71e-6 Intelligence (multi-trait analysis); TGCT cis rs11642862 1.000 rs112691371 chr16:30868216 C/T cg02466173 chr16:30829666 NA -0.41 -4.85 -0.4 3.69e-6 Tonsillectomy; TGCT cis rs2153535 0.580 rs6597332 chr6:8504748 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.44e-13 Vitiligo; TGCT cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg12310025 chr6:25882481 NA -0.54 -4.78 -0.39 4.83e-6 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.731 rs5745445 chr1:76344332 G/A cg10523679 chr1:76189770 ACADM 0.85 7.88 0.58 1.45e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9560113 0.573 rs9560132 chr13:112237456 C/T cg10483660 chr13:112241077 NA 0.31 4.92 0.4 2.67e-6 Menarche (age at onset); TGCT cis rs758129 1.000 rs758129 chr15:89900887 A/G cg24365117 chr15:89879190 POLG -0.31 -4.54 -0.38 1.3e-5 Schizophrenia; TGCT cis rs9325144 0.647 rs11168741 chr12:38989120 C/T cg26384229 chr12:38710491 ALG10B -0.58 -5.55 -0.45 1.67e-7 Morning vs. evening chronotype; TGCT cis rs9814567 1.000 rs2887797 chr3:134202506 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -10.02 -0.67 1.12e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6912958 0.559 rs2985039 chr6:88041757 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.45 5.88 0.47 3.49e-8 Monocyte percentage of white cells; TGCT cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs2880765 0.835 rs6497206 chr15:86029225 A/G cg13263323 chr15:86062960 AKAP13 -0.22 -4.7 -0.39 6.86e-6 Coronary artery disease; TGCT cis rs826838 0.935 rs10875816 chr12:38955014 C/A cg26384229 chr12:38710491 ALG10B 1.03 10.33 0.68 1.97e-18 Heart rate; TGCT cis rs8031584 0.678 rs798125 chr15:31116800 C/T cg08109568 chr15:31115862 NA 0.4 5.22 0.42 7.31e-7 Huntington's disease progression; TGCT cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg17971929 chr21:40555470 PSMG1 0.68 6.1 0.48 1.28e-8 Cognitive function; TGCT cis rs12579753 0.879 rs1987116 chr12:82156478 G/A cg21231944 chr12:82153410 PPFIA2 -0.34 -4.52 -0.38 1.4e-5 Resting heart rate; TGCT cis rs7103648 0.695 rs10838726 chr11:47568344 C/G cg20307385 chr11:47447363 PSMC3 0.88 8.62 0.61 2.57e-14 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs2692947 0.537 rs72821435 chr2:96187935 C/T cg23100626 chr2:96804247 ASTL 0.45 5.33 0.43 4.5e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs644799 0.622 rs1255167 chr11:95500213 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.6 6.5 0.5 1.78e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs5760092 0.572 rs738806 chr22:24234172 A/G cg25703541 chr22:24373054 LOC391322 -0.59 -4.73 -0.39 5.92e-6 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9527 0.615 rs11191401 chr10:104573403 A/G cg15744005 chr10:104629667 AS3MT -0.49 -5.76 -0.46 6.12e-8 Arsenic metabolism; TGCT cis rs76419734 0.558 rs2305212 chr4:106534691 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.78 4.45 0.37 1.87e-5 Post bronchodilator FEV1; TGCT cis rs7954584 0.531 rs6486781 chr12:122318985 A/C cg21016266 chr12:122356598 WDR66 0.43 5.65 0.45 1.04e-7 Mean corpuscular volume; TGCT cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg06634786 chr22:41940651 POLR3H -0.86 -8.34 -0.6 1.18e-13 Vitiligo; TGCT cis rs6088580 0.619 rs1205335 chr20:32927507 C/T cg06115741 chr20:33292138 TP53INP2 -0.55 -4.84 -0.4 3.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg03517284 chr6:25882590 NA -0.63 -6.57 -0.51 1.26e-9 Blood metabolite levels; TGCT cis rs4849845 0.653 rs3925970 chr2:121018153 C/A cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs4654899 1.000 rs7543126 chr1:21406088 T/G cg01072550 chr1:21505969 NA -0.51 -8.1 -0.59 4.46e-13 Superior frontal gyrus grey matter volume; TGCT cis rs28595532 0.920 rs116246794 chr4:119732491 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7267979 0.586 rs1007707 chr20:25190598 A/G cg14121845 chr20:25566513 NINL 0.45 4.86 0.4 3.51e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12497850 0.897 rs9850134 chr3:48957147 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs7666738 0.962 rs2865991 chr4:99067369 C/A cg17366294 chr4:99064904 C4orf37 0.73 6.51 0.5 1.72e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg03264133 chr6:25882463 NA -0.66 -6.01 -0.47 1.94e-8 Intelligence (multi-trait analysis); TGCT cis rs12052801 0.648 rs7599687 chr2:68348011 C/T cg00095431 chr2:67775781 NA -0.32 -4.63 -0.38 9.18e-6 Schizophrenia; TGCT cis rs12541335 0.639 rs4872468 chr8:22179844 G/C cg07298985 chr8:22133076 PIWIL2 0.33 5.29 0.43 5.4e-7 Hypertriglyceridemia; TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg07332563 chr6:291687 DUSP22 -0.75 -7.74 -0.57 3.04e-12 Menopause (age at onset); TGCT cis rs4072705 0.646 rs915034 chr9:127244955 G/A cg13476313 chr9:127244764 NR5A1 0.31 5.09 0.42 1.29e-6 Menarche (age at onset); TGCT trans rs210152 0.588 rs1755040 chr6:33495175 A/C cg08795360 chr21:41033440 B3GALT5 -0.44 -6.68 -0.51 7.12e-10 Schizophrenia; TGCT cis rs11190604 0.767 rs10883489 chr10:102194532 T/C cg16342193 chr10:102329863 NA -0.41 -5.22 -0.42 7.22e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9916302 0.706 rs12950186 chr17:37393395 A/C cg07936489 chr17:37558343 FBXL20 -0.83 -6.26 -0.49 5.7e-9 Glomerular filtration rate (creatinine); TGCT cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs7635838 0.855 rs9816564 chr3:11475297 T/C cg00170343 chr3:11313890 ATG7 0.66 6.3 0.49 4.75e-9 HDL cholesterol; TGCT cis rs2070488 0.775 rs4679066 chr3:38568527 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.89 -0.53 2.46e-10 Electrocardiographic conduction measures; TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.54 -0.65 1.69e-16 Platelet count; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg08736216 chr1:53307985 ZYG11A -0.23 -4.7 -0.39 6.81e-6 Monocyte count; TGCT cis rs986417 0.748 rs4381505 chr14:61035968 C/T cg27398547 chr14:60952738 C14orf39 1.33 10.37 0.68 1.56e-18 Gut microbiota (bacterial taxa); TGCT cis rs9894429 0.546 rs9906979 chr17:79608765 A/G cg21028142 chr17:79581711 NPLOC4 0.29 6.01 0.48 1.9e-8 Eye color traits; TGCT cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg09436375 chr6:42928200 GNMT -0.39 -5.03 -0.41 1.67e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2067615 0.524 rs10778500 chr12:107074410 T/A cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs4654899 1.000 rs7550267 chr1:21448792 T/C cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs11096990 0.892 rs6531696 chr4:39191754 A/G ch.4.37949012R chr4:38272617 NA -0.38 -4.62 -0.38 9.31e-6 Cognitive function; TGCT cis rs739496 0.947 rs3742003 chr12:111844218 G/A cg10833066 chr12:111807467 FAM109A 0.37 5.54 0.45 1.76e-7 Platelet count; TGCT cis rs868036 0.672 rs7175517 chr15:68077630 A/G cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs13064411 0.696 rs6438156 chr3:113206929 C/A cg18753928 chr3:113234510 CCDC52 -0.7 -5.64 -0.45 1.08e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs11190604 1.000 rs4919464 chr10:102221195 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1008375 0.606 rs6828925 chr4:17561139 C/T cg16339924 chr4:17578868 LAP3 0.59 5.03 0.41 1.66e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg25703541 chr22:24373054 LOC391322 0.84 7.2 0.54 5.15e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2760061 0.583 rs697763 chr1:228192622 G/C cg02753203 chr1:228287806 NA 0.38 7.5 0.56 1.04e-11 Diastolic blood pressure; TGCT cis rs1552244 0.515 rs6768768 chr3:10177653 C/T cg00149659 chr3:10157352 C3orf10 0.95 7.06 0.54 1.07e-10 Alzheimer's disease; TGCT trans rs525455 1.000 rs1659839 chr10:13103022 G/T cg21721093 chr17:8906386 NA 0.64 6.7 0.52 6.38e-10 Platelet aggregation; TGCT cis rs9611565 0.879 rs5758311 chr22:41759375 G/T cg06634786 chr22:41940651 POLR3H -0.8 -7.65 -0.57 4.81e-12 Vitiligo; TGCT cis rs6840360 0.550 rs4696289 chr4:152621237 C/T cg17479576 chr4:152424074 FAM160A1 -0.67 -6.69 -0.52 6.7e-10 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs72945132 0.882 rs2276001 chr11:70181560 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9359856 0.510 rs6454775 chr6:90465000 A/T cg13799429 chr6:90582589 CASP8AP2 0.45 4.66 0.39 7.9e-6 Bipolar disorder; TGCT cis rs6840360 0.642 rs2724578 chr4:152367304 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs6933660 0.800 rs9383900 chr6:151782816 A/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.95 -10.84 -0.7 1.14e-19 Menarche (age at onset); TGCT cis rs763014 0.931 rs7192508 chr16:630367 C/T cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs7428 0.527 rs7608892 chr2:85542718 G/A cg03728395 chr2:85555865 TGOLN2 -0.32 -5.51 -0.44 2.02e-7 Ear protrusion; TGCT cis rs17376456 0.542 rs35672980 chr5:93284877 A/T cg25358565 chr5:93447407 FAM172A -0.62 -5.97 -0.47 2.33e-8 Diabetic retinopathy; TGCT cis rs8177253 0.507 rs4241357 chr3:133475563 A/C cg08048268 chr3:133502702 NA 0.38 4.84 0.4 3.76e-6 Iron status biomarkers; TGCT cis rs6088580 0.713 rs1884669 chr20:33171287 G/A cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Glomerular filtration rate (creatinine); TGCT cis rs3820928 0.874 rs56324594 chr2:227868854 C/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg24829409 chr8:58192753 C8orf71 -0.57 -4.73 -0.39 6.09e-6 Developmental language disorder (linguistic errors); TGCT cis rs10479542 1.000 rs10479542 chr5:178981241 T/A cg19626725 chr5:178986131 RUFY1 0.45 5.7 0.46 8.26e-8 Lung cancer; TGCT cis rs7914558 1.000 rs7077097 chr10:104945463 G/A cg04362960 chr10:104952993 NT5C2 0.61 5.47 0.44 2.42e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs832540 0.593 rs96844 chr5:56196604 G/A cg24531977 chr5:56204891 C5orf35 -0.56 -5.05 -0.41 1.57e-6 Coronary artery disease; TGCT cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg13695892 chr22:41940480 POLR3H -0.77 -7.47 -0.56 1.24e-11 Vitiligo; TGCT cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg02487422 chr3:49467188 NICN1 0.53 5.12 0.42 1.13e-6 Menarche (age at onset); TGCT cis rs35306767 0.807 rs72778228 chr10:938435 A/G cg26597838 chr10:835615 NA 0.81 12.42 0.74 1.61e-23 Eosinophil percentage of granulocytes; TGCT cis rs559928 0.606 rs55942618 chr11:63936005 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.56 0.38 1.22e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg02073558 chr3:44770973 ZNF501 0.57 5.5 0.44 2.07e-7 Depressive symptoms; TGCT cis rs4711350 0.734 rs7739273 chr6:33758065 G/A cg13859433 chr6:33739653 LEMD2 -0.33 -4.93 -0.4 2.6e-6 Schizophrenia; TGCT cis rs1799949 0.931 rs34474989 chr17:41445410 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.45 4.84 0.4 3.81e-6 Menopause (age at onset); TGCT cis rs2688608 0.592 rs7909544 chr10:75484004 G/C cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs950776 0.518 rs3813572 chr15:78832588 T/C cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg07636037 chr3:49044803 WDR6 0.88 9.28 0.64 6.89e-16 Menarche (age at onset); TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg24675658 chr1:53192096 ZYG11B -0.75 -9.16 -0.64 1.38e-15 Monocyte count; TGCT cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg27454412 chr7:1067447 C7orf50 0.6 4.73 0.39 5.89e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9929218 0.559 rs12923775 chr16:68756450 C/T cg01251360 chr16:68772225 CDH1 -0.26 -4.77 -0.39 5.14e-6 Colorectal cancer; TGCT cis rs9894429 0.646 rs7405870 chr17:79617284 G/A cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs950776 0.531 rs12915652 chr15:78831928 G/A cg06917634 chr15:78832804 PSMA4 0.95 9.33 0.64 5.42e-16 Sudden cardiac arrest; TGCT cis rs6988636 1.000 rs13261066 chr8:124190276 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg24250549 chr1:154909240 PMVK 0.62 6.28 0.49 5.29e-9 Prostate cancer; TGCT cis rs12220238 1.000 rs12359456 chr10:75937994 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7552404 0.731 rs12078299 chr1:76365764 T/A cg10523679 chr1:76189770 ACADM 0.82 7.17 0.54 5.99e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10089 1.000 rs4836370 chr5:127499224 A/G cg19767477 chr5:127420684 SLC12A2 -0.44 -4.63 -0.38 9.27e-6 Ileal carcinoids; TGCT cis rs2486012 1.000 rs3011231 chr1:44342235 A/G cg12908607 chr1:44402522 ARTN -0.73 -5.67 -0.45 9.51e-8 Intelligence (multi-trait analysis); TGCT cis rs763121 0.785 rs6001203 chr22:39099602 T/C cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT cis rs1997103 1.000 rs10228182 chr7:55406695 A/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs3749237 0.555 rs7637665 chr3:49552295 T/C cg03060546 chr3:49711283 APEH 0.75 8.62 0.61 2.66e-14 Resting heart rate; TGCT cis rs56309584 0.715 rs78286057 chr17:8152039 C/A cg08322244 chr17:8066669 VAMP2 -0.58 -5.43 -0.44 2.79e-7 Initial pursuit acceleration; TGCT cis rs6690583 0.562 rs76839162 chr1:85530021 A/G cg20280350 chr1:85513789 MCOLN3 -0.72 -4.59 -0.38 1.08e-5 Serum sulfate level; TGCT cis rs11122272 0.735 rs2790892 chr1:231512771 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs3796352 0.571 rs71301816 chr3:53142071 G/A cg15956490 chr3:53032818 SFMBT1 0.52 6.07 0.48 1.43e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11785400 0.701 rs9721143 chr8:143727511 A/T cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs9486715 0.929 rs7775721 chr6:97056979 C/T cg06623918 chr6:96969491 KIAA0776 -1.13 -15.01 -0.8 1.13e-29 Headache; TGCT cis rs9653442 0.593 rs6737502 chr2:100862903 C/T cg22139774 chr2:100720529 AFF3 -0.39 -6.4 -0.5 2.93e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1525293 0.659 rs12698983 chr7:70509647 G/A cg21135135 chr7:70597687 WBSCR17 0.48 4.59 0.38 1.05e-5 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs394563 0.726 rs6942381 chr6:149662991 G/C cg11245181 chr6:149772854 ZC3H12D 0.29 4.7 0.39 6.79e-6 Dupuytren's disease; TGCT cis rs1692580 0.807 rs4648628 chr1:2203490 C/T cg21194808 chr1:2205498 SKI 0.29 5.54 0.45 1.72e-7 Coronary artery disease; TGCT cis rs12541335 0.639 rs13257108 chr8:22165043 T/C cg18135555 chr8:22132992 PIWIL2 0.3 6.2 0.49 7.71e-9 Hypertriglyceridemia; TGCT cis rs763121 0.819 rs5757126 chr22:38923675 T/C cg06022373 chr22:39101656 GTPBP1 0.76 7.29 0.55 3.15e-11 Menopause (age at onset); TGCT cis rs4727443 0.966 rs66748925 chr7:99589843 A/G cg13334819 chr7:99746414 C7orf59 0.54 4.5 0.37 1.55e-5 Interstitial lung disease; TGCT cis rs5167 0.504 rs8100120 chr19:45466058 T/C cg13119609 chr19:45449297 APOC2 0.23 4.44 0.37 1.94e-5 Blood protein levels; TGCT cis rs11077998 0.869 rs6502123 chr17:80532170 T/C cg10255544 chr17:80519551 FOXK2 0.24 4.51 0.38 1.5e-5 Reticulocyte fraction of red cells; TGCT cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg10802521 chr3:52805072 NEK4 -0.66 -7.8 -0.57 2.22e-12 Bipolar disorder; TGCT cis rs308403 0.509 rs6811183 chr4:123671551 T/G cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.84 0.73 4.22e-22 Blood protein levels; TGCT cis rs9467603 0.800 rs4236040 chr6:25761209 T/C cg16898833 chr6:26189333 HIST1H4D -0.99 -4.75 -0.39 5.62e-6 Intelligence (multi-trait analysis); TGCT cis rs4721295 0.573 rs3779000 chr7:2181628 G/A cg22963979 chr7:1858916 MAD1L1 -0.38 -5.96 -0.47 2.46e-8 Schizophrenia, schizoaffective disorder or bipolar disorder; TGCT cis rs250677 0.652 rs250680 chr5:148436024 T/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs11030122 0.687 rs10835521 chr11:4056004 A/T cg18678763 chr11:4115507 RRM1 -0.45 -5.6 -0.45 1.3e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs240764 0.658 rs9485410 chr6:101261007 A/G cg21058520 chr6:100914733 NA -0.34 -4.47 -0.37 1.72e-5 Neuroticism; TGCT cis rs2075165 0.836 rs7512751 chr1:156234439 T/G cg20302342 chr1:156215951 PAQR6 0.38 5.44 0.44 2.72e-7 Tonsillectomy; TGCT cis rs12681287 0.888 rs13042 chr8:87484913 G/A cg27223183 chr8:87520930 FAM82B -0.8 -5.99 -0.47 2.13e-8 Caudate activity during reward; TGCT cis rs675209 0.635 rs1334577 chr6:7211751 G/A cg27097018 chr6:6320614 F13A1 0.37 5.24 0.43 6.62e-7 Urate levels; TGCT cis rs1691799 0.899 rs1168322 chr12:66743769 C/T cg16791601 chr12:66731901 HELB -0.28 -6.18 -0.49 8.52e-9 White blood cell count (basophil); TGCT cis rs6087990 0.899 rs4911262 chr20:31393352 G/A cg13636640 chr20:31349939 DNMT3B 1.09 15.71 0.82 2.82e-31 Ulcerative colitis; TGCT cis rs9308731 0.931 rs616130 chr2:111912681 C/A cg04202892 chr2:111875749 ACOXL 0.43 4.58 0.38 1.13e-5 Chronic lymphocytic leukemia; TGCT cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg06634786 chr22:41940651 POLR3H -0.86 -8.32 -0.6 1.34e-13 Vitiligo; TGCT trans rs1974653 0.672 rs9605063 chr22:20090038 A/C cg08822737 chr17:71088851 SLC39A11 0.82 7.04 0.53 1.17e-10 Schizophrenia; TGCT cis rs2795502 0.766 rs947549 chr10:43265880 G/C cg20628663 chr10:43360327 NA -0.41 -4.81 -0.4 4.3e-6 Blood protein levels; TGCT cis rs10782582 0.609 rs1628063 chr1:76391646 A/G cg03433033 chr1:76189801 ACADM -0.47 -4.65 -0.39 8.23e-6 Daytime sleep phenotypes; TGCT cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs57221529 0.709 rs4957056 chr5:570105 T/C cg09021430 chr5:549028 NA -0.41 -5.69 -0.46 8.58e-8 Lung disease severity in cystic fibrosis; TGCT cis rs9733 0.596 rs72702573 chr1:150689050 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs11627546 0.528 rs59997769 chr14:70362154 T/C cg10496350 chr14:71275911 MAP3K9 -1.01 -4.93 -0.41 2.54e-6 Red blood cell traits; TGCT cis rs208520 0.874 rs208481 chr6:66922636 A/G cg07460842 chr6:66804631 NA -0.9 -9.16 -0.64 1.34e-15 Exhaled nitric oxide output; TGCT cis rs250677 0.687 rs384979 chr5:148459267 C/T cg18129178 chr5:148520854 ABLIM3 0.42 5.87 0.47 3.8e-8 Breast cancer; TGCT cis rs4478858 0.595 rs4949387 chr1:31803440 T/A cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg15691649 chr6:25882328 NA -0.42 -5.35 -0.43 4.11e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs880472 chr4:98922595 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 1.000 rs2482927 chr20:25327151 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs916888 0.821 rs70602 chr17:44859715 T/C cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs4919669 0.668 rs10883757 chr10:104400133 C/T cg24066601 chr6:26271455 HIST1H3G 0.7 6.69 0.51 6.98e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs6920965 0.602 rs10872302 chr6:126180631 G/T cg05901451 chr6:126070800 HEY2 -0.6 -6.29 -0.49 4.97e-9 High light scatter reticulocyte count; TGCT cis rs7635838 0.785 rs2594972 chr3:11397417 A/G cg00170343 chr3:11313890 ATG7 0.64 6.15 0.48 9.73e-9 HDL cholesterol; TGCT cis rs11249608 0.548 rs17078988 chr5:178459283 A/G cg21905437 chr5:178450457 ZNF879 0.44 4.72 0.39 6.21e-6 Pubertal anthropometrics; TGCT cis rs12579753 0.912 rs4417392 chr12:82158722 C/A cg07988820 chr12:82153109 PPFIA2 -0.68 -7.51 -0.56 1.01e-11 Resting heart rate; TGCT cis rs6540559 0.605 rs3753518 chr1:209977964 G/C cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg03806693 chr22:41940476 POLR3H -1.0 -11.1 -0.71 2.65e-20 Vitiligo; TGCT cis rs4478858 0.735 rs4949389 chr1:31824023 A/G cg00250761 chr1:31883323 NA 0.25 4.45 0.37 1.87e-5 Alcohol dependence; TGCT cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17376456 0.877 rs13170509 chr5:93378564 T/C cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs317689 0.918 rs610192 chr12:69739941 T/C cg19645103 chr12:69753606 YEATS4 -0.58 -4.66 -0.39 7.99e-6 Response to diuretic therapy; TGCT cis rs4689388 0.926 rs9998519 chr4:6292909 C/T cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9660992 0.710 rs1768587 chr1:205236432 C/T cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs56104184 0.775 rs117016425 chr19:49400216 C/T cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs992157 0.965 rs13419763 chr2:219134950 C/T cg00012203 chr2:219082015 ARPC2 0.78 8.24 0.6 2.02e-13 Colorectal cancer; TGCT cis rs11118844 0.793 rs4433402 chr1:221946172 A/G cg04222084 chr1:221915650 DUSP10 -0.7 -4.96 -0.41 2.25e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs9858542 1.000 rs9812791 chr3:49682311 G/A cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6570726 0.791 rs387376 chr6:145822565 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1483890 0.632 rs111868405 chr3:69412154 A/T cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs2721195 0.743 rs2306386 chr8:145742879 T/C cg17328964 chr8:145687451 CYHR1 -0.39 -5.4 -0.44 3.32e-7 Age at first birth; TGCT cis rs6831352 0.918 rs29001211 chr4:100051941 C/T cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs2072499 0.750 rs57056972 chr1:156159064 C/A cg25208724 chr1:156163844 SLC25A44 1.01 9.25 0.64 8.38e-16 Testicular germ cell tumor; TGCT cis rs1008375 1.000 rs114490726 chr4:17680898 T/C cg18681998 chr4:17616180 MED28 0.91 10.53 0.69 6.55e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7586879 0.687 rs11892869 chr2:25096692 A/T cg01884057 chr2:25150051 NA 0.31 5.94 0.47 2.72e-8 Body mass index; TGCT cis rs1008375 0.898 rs4698620 chr4:17587361 C/T cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7824557 0.527 rs2736298 chr8:11235136 C/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.42e-10 Retinal vascular caliber; TGCT cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg12756686 chr19:29218302 NA 0.78 6.69 0.51 6.93e-10 Methadone dose in opioid dependence; TGCT cis rs7100689 0.725 rs10749574 chr10:82136856 T/C cg01528321 chr10:82214614 TSPAN14 0.87 8.35 0.6 1.14e-13 Post bronchodilator FEV1; TGCT cis rs1008375 0.966 rs10939735 chr4:17578891 A/G cg16339924 chr4:17578868 LAP3 0.83 7.21 0.54 4.92e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7412746 0.658 rs72704652 chr1:150819470 A/G cg04414720 chr1:150670196 GOLPH3L 0.39 4.75 0.39 5.55e-6 Melanoma; TGCT cis rs6964587 1.000 rs4644173 chr7:91759597 A/G cg17063962 chr7:91808500 NA 0.89 9.48 0.65 2.27e-16 Breast cancer; TGCT cis rs2898290 0.506 rs2736311 chr8:11252170 C/T cg21775007 chr8:11205619 TDH -0.62 -6.23 -0.49 6.5e-9 Systolic blood pressure; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg06753367 chr22:24256600 NA 0.24 4.51 0.38 1.5e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg19536664 chr17:6899085 ALOX12 0.39 6.35 0.5 3.67e-9 Tonsillectomy; TGCT cis rs6050267 0.556 rs62217177 chr20:25012178 A/G cg26195577 chr20:24973756 C20orf3 0.9 6.16 0.48 9.54e-9 Cognitive performance; TGCT cis rs6714710 0.603 rs11684749 chr2:98420142 G/C cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7917772 0.503 rs7904955 chr10:104367092 C/T cg05855489 chr10:104503620 C10orf26 -0.6 -5.28 -0.43 5.49e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs597539 0.652 rs613128 chr11:68638058 G/T cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs35306767 0.761 rs1871621 chr10:1049596 C/T cg18964960 chr10:1102726 WDR37 0.78 5.46 0.44 2.45e-7 Eosinophil percentage of granulocytes; TGCT trans rs10506458 0.915 rs1009540 chr12:63414872 C/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.59 -0.56 6.63e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs763121 0.889 rs9607557 chr22:39040279 G/A cg06022373 chr22:39101656 GTPBP1 0.8 8.17 0.59 2.97e-13 Menopause (age at onset); TGCT cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg06221963 chr1:154839813 KCNN3 -0.76 -13.06 -0.76 4.81e-25 Prostate cancer; TGCT cis rs75686122 0.892 rs75784460 chr8:104710728 T/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs10876993 0.890 rs774891 chr12:58068571 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.91 -0.47 3.12e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7727544 0.606 rs2631360 chr5:131707429 A/G cg24060327 chr5:131705240 SLC22A5 -0.51 -5.41 -0.44 3.16e-7 Blood metabolite levels; TGCT cis rs597539 0.652 rs553875 chr11:68695144 T/G cg21963583 chr11:68658836 MRPL21 0.36 5.97 0.47 2.28e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.1 -0.42 1.22e-6 Electroencephalogram traits; TGCT cis rs9929218 0.906 rs9933844 chr16:68747001 G/A cg01251360 chr16:68772225 CDH1 0.29 4.71 0.39 6.63e-6 Colorectal cancer; TGCT cis rs4851254 0.961 rs11680586 chr2:100746207 G/T cg04109781 chr2:100722022 AFF3 0.42 4.56 0.38 1.2e-5 Intelligence (multi-trait analysis); TGCT cis rs11098499 0.570 rs6832740 chr4:120546136 T/C cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs2721195 0.816 rs4251689 chr8:145741130 C/T cg17328964 chr8:145687451 CYHR1 -0.44 -6.23 -0.49 6.72e-9 Age at first birth; TGCT cis rs11030122 0.673 rs11030660 chr11:4043268 T/C cg18678763 chr11:4115507 RRM1 -0.49 -6.11 -0.48 1.19e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs2688608 0.592 rs2306328 chr10:75579510 C/T cg15838173 chr10:75533400 FUT11 -0.3 -4.83 -0.4 3.97e-6 Inflammatory bowel disease; TGCT cis rs7647973 0.710 rs12637313 chr3:49645458 A/G cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg17178900 chr1:205818956 PM20D1 0.67 9.22 0.64 9.59e-16 Menarche (age at onset); TGCT cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg01411255 chr17:61851458 DDX42;CCDC47 1.09 13.7 0.78 1.38e-26 Height; TGCT cis rs6598955 0.670 rs3795685 chr1:26601385 A/G cg04990556 chr1:26633338 UBXN11 0.92 11.91 0.73 2.89e-22 Obesity-related traits; TGCT cis rs875971 0.895 rs1974769 chr7:65950614 G/A cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs7226408 0.857 rs11660125 chr18:34476622 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6121246 0.559 rs6058352 chr20:30269179 T/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg26354017 chr1:205819088 PM20D1 0.53 6.31 0.49 4.43e-9 Menarche (age at onset); TGCT cis rs11122272 0.701 rs2883799 chr1:231531166 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT cis rs13223928 0.538 rs10951042 chr7:3139417 T/C cg19214707 chr7:3157722 NA -0.47 -6.77 -0.52 4.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs13108904 0.846 rs3775100 chr4:1225106 T/C cg05665937 chr4:1216051 CTBP1 0.25 4.96 0.41 2.28e-6 Obesity-related traits; TGCT cis rs7647973 1.000 rs6805609 chr3:49471522 C/G cg07636037 chr3:49044803 WDR6 -0.76 -5.69 -0.45 8.74e-8 Menarche (age at onset); TGCT trans rs73720034 1.000 rs78520622 chr7:125566859 G/A cg18231848 chr1:26499103 NA 0.51 6.66 0.51 8.09e-10 Response to selective serotonin reuptake inhibitors and depression; TGCT cis rs7412746 0.658 rs10888397 chr1:150886752 A/G cg04414720 chr1:150670196 GOLPH3L -0.36 -4.48 -0.37 1.66e-5 Melanoma; TGCT cis rs7179456 0.513 rs640704 chr15:59049021 A/G cg05156742 chr15:59063176 FAM63B 0.51 4.84 0.4 3.8e-6 Asperger disorder; TGCT cis rs9357506 1.000 rs716493 chr6:46307942 C/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs4499344 0.730 rs453804 chr19:33105612 T/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.86 9.0 0.63 3.29e-15 Mean platelet volume; TGCT cis rs4478858 0.684 rs11578407 chr1:31728543 A/G cg07478791 chr1:31886160 SERINC2 -0.48 -4.61 -0.38 9.77e-6 Alcohol dependence; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg23131131 chr22:24373011 LOC391322 -0.6 -5.97 -0.47 2.29e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9868809 0.542 rs9873726 chr3:48712367 C/T cg00383909 chr3:49044727 WDR6 0.88 5.3 0.43 5.17e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7208859 0.623 rs216446 chr17:28933718 T/G cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs66573146 1.000 rs6812391 chr4:6963893 G/A cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs8100891 0.614 rs6510243 chr19:32833671 A/G cg16662424 chr19:32837316 ZNF507 -0.41 -5.0 -0.41 1.93e-6 Neuroticism; TGCT cis rs9527 0.590 rs11191578 chr10:104902337 A/T cg15744005 chr10:104629667 AS3MT -0.42 -4.86 -0.4 3.41e-6 Arsenic metabolism; TGCT cis rs911263 0.887 rs8015139 chr14:68739301 G/T cg18825221 chr14:68749962 RAD51L1 -0.28 -5.53 -0.44 1.85e-7 Primary biliary cholangitis; TGCT cis rs6088580 0.634 rs6141471 chr20:33006730 A/G cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs6121246 0.529 rs6060171 chr20:30183269 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.28 -0.49 5.3e-9 Mean corpuscular hemoglobin; TGCT cis rs2836974 0.897 rs35064900 chr21:40555492 A/G cg11890956 chr21:40555474 PSMG1 1.12 12.26 0.74 4.02e-23 Cognitive function; TGCT cis rs4499344 0.604 rs259287 chr19:33164859 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.87 9.38 0.64 3.95e-16 Mean platelet volume; TGCT cis rs4819052 0.851 rs8126930 chr21:46671715 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.74 0.52 5.34e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7586879 0.616 rs13410999 chr2:25097939 T/C cg01884057 chr2:25150051 NA 0.31 5.94 0.47 2.72e-8 Body mass index; TGCT cis rs614226 0.872 rs12307148 chr12:120903179 T/C cg10072921 chr12:121022843 NA 0.45 4.69 0.39 7.09e-6 Type 1 diabetes nephropathy; TGCT cis rs3806843 0.706 rs1089305 chr5:140066306 T/C cg19875535 chr5:140030758 IK -0.36 -6.15 -0.48 9.57e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2370759 1.000 rs79578760 chr10:32611264 C/A cg01819863 chr10:32635814 EPC1 1.03 10.07 0.67 8.33e-18 Sexual dysfunction (female); TGCT cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs478304 0.934 rs603645 chr11:65533000 A/C cg27068330 chr11:65405492 SIPA1 0.74 7.41 0.55 1.67e-11 Acne (severe); TGCT cis rs8013055 0.846 rs35590487 chr14:105989599 C/T cg23356831 chr14:105996513 TMEM121 0.34 4.98 0.41 2.05e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7267979 0.966 rs6050611 chr20:25414419 A/G cg16686733 chr20:25566563 NINL 0.56 5.57 0.45 1.48e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7845219 0.555 rs1129152 chr8:95888307 C/T cg23172400 chr8:95962367 TP53INP1 -0.34 -5.02 -0.41 1.72e-6 Type 2 diabetes; TGCT cis rs3008870 1.000 rs2182143 chr1:67378936 T/C cg03991309 chr1:68237761 GNG12 0.27 4.68 0.39 7.28e-6 Lymphocyte percentage of white cells; TGCT cis rs17122693 0.551 rs3015456 chr14:51059923 T/C cg04730355 chr14:51134070 SAV1 1.19 12.02 0.73 1.56e-22 Cognitive performance; TGCT cis rs7119038 0.818 rs77209083 chr11:118607569 A/G cg19308663 chr11:118741387 NA 0.26 4.86 0.4 3.52e-6 Sjögren's syndrome; TGCT cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg20637647 chr7:64974828 NA 1.0 5.57 0.45 1.53e-7 Diabetic kidney disease; TGCT cis rs7714584 1.000 rs11950957 chr5:150253914 G/A cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs9303401 0.659 rs714959 chr17:56628601 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs6564219 1 rs6564219 chr16:75222006 G/C cg09066997 chr16:75300724 BCAR1 0.27 4.79 0.39 4.75e-6 Alcoholic chronic pancreatitis; TGCT cis rs2692947 0.508 rs2216793 chr2:96196322 A/G cg23100626 chr2:96804247 ASTL 0.45 5.34 0.43 4.21e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6088580 0.668 rs1205337 chr20:32926041 T/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.84 -0.4 3.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs9467773 1.000 rs9393729 chr6:26514166 C/T cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs6977660 0.607 rs12113916 chr7:19781424 G/T cg07541023 chr7:19748670 TWISTNB 0.83 4.69 0.39 7.01e-6 Thyroid stimulating hormone; TGCT cis rs931127 0.747 rs11820062 chr11:65429936 T/C cg17480646 chr11:65405466 SIPA1 -0.42 -5.47 -0.44 2.34e-7 Systemic lupus erythematosus; TGCT cis rs394563 0.591 rs805026 chr6:149728254 G/C cg16235748 chr6:149772707 ZC3H12D -0.45 -5.01 -0.41 1.8e-6 Dupuytren's disease; TGCT cis rs7020830 0.861 rs13295981 chr9:37330067 C/T cg14235030 chr9:37121269 ZCCHC7 0.41 4.51 0.38 1.49e-5 Schizophrenia; TGCT cis rs4319547 0.695 rs11836188 chr12:122865507 T/C cg05707623 chr12:122985044 ZCCHC8 0.62 4.83 0.4 3.91e-6 Body mass index; TGCT cis rs9300255 0.602 rs1727296 chr12:123647725 G/C cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs7147624 1.000 rs2898816 chr14:66008160 T/C cg03016385 chr14:66212404 NA -0.49 -7.08 -0.54 9.33e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs74233809 1.000 rs11191505 chr10:104766891 C/T cg05855489 chr10:104503620 C10orf26 0.75 4.47 0.37 1.72e-5 Birth weight; TGCT cis rs9527 0.662 rs743575 chr10:104594906 T/G cg15744005 chr10:104629667 AS3MT -0.46 -5.74 -0.46 7e-8 Arsenic metabolism; TGCT cis rs1950500 0.617 rs10362 chr14:24846961 G/T cg07162820 chr14:24837146 NFATC4 0.42 4.47 0.37 1.77e-5 Height; TGCT cis rs642803 0.551 rs1308020 chr11:65497558 G/A cg27068330 chr11:65405492 SIPA1 0.65 5.71 0.46 7.78e-8 Urate levels; TGCT cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs6988636 1.000 rs11993411 chr8:124180537 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.46 -0.44 2.5e-7 Urinary uromodulin levels; TGCT cis rs478304 0.651 rs11604451 chr11:65551710 C/T cg17480646 chr11:65405466 SIPA1 -0.55 -6.45 -0.5 2.28e-9 Acne (severe); TGCT cis rs7542091 0.637 rs9429826 chr1:210052146 G/A cg22029157 chr1:209979665 IRF6 0.62 5.96 0.47 2.44e-8 Monobrow; TGCT cis rs10984561 0.881 rs58379881 chr9:122243802 C/T cg14242995 chr9:122249943 NA 0.75 6.45 0.5 2.25e-9 Pulmonary function decline; TGCT cis rs9929218 0.508 rs6499194 chr16:68744100 T/C cg01251360 chr16:68772225 CDH1 -0.25 -4.57 -0.38 1.18e-5 Colorectal cancer; TGCT cis rs6964587 0.934 rs35968894 chr7:91762145 A/G cg17063962 chr7:91808500 NA 0.84 8.15 0.59 3.39e-13 Breast cancer; TGCT cis rs3796352 1.000 rs13078971 chr3:53103645 G/C cg07884673 chr3:53033167 SFMBT1 0.59 6.04 0.48 1.63e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9427116 0.502 rs3766922 chr1:154577055 A/C cg17218026 chr1:154582156 ADAR 0.29 6.99 0.53 1.47e-10 Blood protein levels; TGCT cis rs10949834 1.000 rs10949835 chr7:73488922 A/G cg07137043 chr7:73588983 EIF4H -0.74 -4.6 -0.38 1.03e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs7674212 0.541 rs2623070 chr4:104037388 A/G cg16532752 chr4:104119610 CENPE 0.6 5.31 0.43 4.97e-7 Type 2 diabetes; TGCT cis rs1580019 0.563 rs13244332 chr7:32537679 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 14.18 0.79 1.03e-27 Cognitive ability; TGCT cis rs6785206 0.527 rs36110719 chr3:128657106 C/A cg25356066 chr3:128598488 ACAD9 -0.74 -4.65 -0.39 8.51e-6 Lymphocyte percentage of white cells; TGCT cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg05552183 chr6:42928497 GNMT 0.52 4.57 0.38 1.17e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4727027 0.933 rs12154382 chr7:148862284 C/T cg23583168 chr7:148888333 NA -0.76 -10.09 -0.67 7.46e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7666738 0.800 rs7684523 chr4:98983175 G/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7582180 0.652 rs11687865 chr2:100947000 T/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs1056053 0.514 rs3099268 chr6:166572826 T/C cg17219086 chr6:166541254 NA -0.19 -4.47 -0.37 1.77e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7542091 1.000 rs7542091 chr1:210031948 G/C cg00989853 chr1:209979345 IRF6 0.4 4.46 0.37 1.81e-5 Monobrow; TGCT cis rs36051895 0.659 rs7025540 chr9:5043152 T/C cg02405213 chr9:5042618 JAK2 -0.78 -10.85 -0.7 1.1e-19 Pediatric autoimmune diseases; TGCT cis rs6500602 0.739 rs4786502 chr16:4537104 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.64 0.45 1.09e-7 Schizophrenia; TGCT cis rs12142240 0.698 rs72677589 chr1:46817770 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7909167 0.661 rs7067627 chr10:25912666 G/T cg00154333 chr10:25012173 ARHGAP21 0.75 5.01 0.41 1.82e-6 Carboplatin disposition in epthelial ovarian cancer; TGCT cis rs1577917 1.000 rs12201571 chr6:86609750 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs11931598 0.509 rs13140943 chr4:6977109 A/G cg26116260 chr4:7069785 GRPEL1 0.59 5.38 0.43 3.59e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs6831352 0.918 rs2851251 chr4:100044111 A/G cg12011299 chr4:100065546 ADH4 0.43 5.02 0.41 1.71e-6 Alcohol dependence; TGCT cis rs6490294 0.583 rs2339973 chr12:112520883 C/T cg10833066 chr12:111807467 FAM109A 0.34 5.22 0.42 7.39e-7 Mean platelet volume; TGCT cis rs981844 0.740 rs7653960 chr4:154697430 T/G cg14289246 chr4:154710475 SFRP2 -0.91 -8.31 -0.6 1.38e-13 Response to statins (LDL cholesterol change); TGCT cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg10047753 chr17:41438598 NA 0.97 9.89 0.66 2.27e-17 Menopause (age at onset); TGCT cis rs4713118 0.866 rs9468217 chr6:27726467 G/A cg20933634 chr6:27740509 NA 0.34 4.75 0.39 5.58e-6 Parkinson's disease; TGCT cis rs7412746 0.658 rs72704652 chr1:150819470 A/G cg09365446 chr1:150670422 GOLPH3L 0.35 4.98 0.41 2.11e-6 Melanoma; TGCT cis rs1691799 0.867 rs1168342 chr12:66758734 A/T cg16791601 chr12:66731901 HELB -0.29 -6.18 -0.49 8.39e-9 White blood cell count (basophil); TGCT cis rs4372836 0.741 rs4563180 chr2:29093695 C/G cg09522027 chr2:28974177 PPP1CB 0.67 6.91 0.53 2.24e-10 Body mass index; TGCT cis rs4986172 0.700 rs71373536 chr17:43221808 G/A cg10701640 chr17:43249399 NA 0.55 6.58 0.51 1.18e-9 Height; TGCT cis rs7617480 0.648 rs14018 chr3:48784270 G/A cg07636037 chr3:49044803 WDR6 0.76 5.93 0.47 2.8e-8 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs66731853 0.769 rs476582 chr1:20894450 A/G cg04087271 chr1:20915334 CDA -0.51 -6.45 -0.5 2.22e-9 Mean corpuscular volume; TGCT cis rs3617 0.573 rs9810807 chr3:52924227 C/T cg11645453 chr3:52864694 ITIH4 -0.28 -5.41 -0.44 3.16e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1629083 0.935 rs1793149 chr11:118127347 A/G cg16594165 chr11:118135105 MPZL2 -0.33 -4.62 -0.38 9.51e-6 Lung cancer; TGCT cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs3008870 0.959 rs2985826 chr1:67412918 G/C cg11518657 chr1:67396239 MIER1 0.54 4.65 0.39 8.44e-6 Lymphocyte percentage of white cells; TGCT cis rs4499344 0.730 rs10413061 chr19:33103278 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.63 0.61 2.53e-14 Mean platelet volume; TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg24675658 chr1:53192096 ZYG11B 0.64 7.31 0.55 2.82e-11 Monocyte count; TGCT cis rs10206020 0.797 rs72778008 chr2:1573182 T/G cg12573674 chr2:1569213 NA -0.49 -5.3 -0.43 5.1e-7 IgG glycosylation; TGCT cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg18402987 chr7:1209562 NA 0.89 7.56 0.56 7.92e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11662586 0.517 rs7228070 chr18:77698967 C/T cg20368463 chr18:77673604 PQLC1 0.57 6.78 0.52 4.33e-10 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs36051895 0.664 rs3780377 chr9:5110899 T/C cg02405213 chr9:5042618 JAK2 -0.74 -9.68 -0.66 7.72e-17 Pediatric autoimmune diseases; TGCT cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs3780486 0.846 rs10116966 chr9:33122370 T/A cg04842962 chr6:43655489 MRPS18A 1.23 15.36 0.81 1.81e-30 IgG glycosylation; TGCT cis rs62380364 0.507 rs34321 chr5:88020319 C/G cg22951263 chr5:87985283 NA -0.57 -6.18 -0.49 8.28e-9 Intelligence (multi-trait analysis); TGCT cis rs4700695 0.719 rs36923 chr5:65464783 G/C cg21114390 chr5:65439923 SFRS12 -0.82 -6.8 -0.52 4.03e-10 Facial morphology (factor 19); TGCT cis rs778371 0.723 rs2592104 chr2:233645970 G/A cg08000102 chr2:233561755 GIGYF2 0.68 7.84 0.58 1.75e-12 Schizophrenia; TGCT cis rs6121246 0.567 rs6058197 chr20:30194899 A/G cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs12142240 0.659 rs67547686 chr1:46832229 G/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.8 -0.4 4.46e-6 Menopause (age at onset); TGCT cis rs17030434 0.906 rs4696491 chr4:154679865 T/C cg14289246 chr4:154710475 SFRP2 0.95 7.5 0.56 1.06e-11 Electrocardiographic conduction measures; TGCT cis rs6912958 0.678 rs9450744 chr6:88280529 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs9467773 0.869 rs9295689 chr6:26455811 T/C cg05738196 chr6:26577821 NA 0.68 7.81 0.57 2.02e-12 Intelligence (multi-trait analysis); TGCT cis rs4072705 0.615 rs7851737 chr9:127247931 G/A cg13476313 chr9:127244764 NR5A1 -0.3 -5.17 -0.42 8.97e-7 Menarche (age at onset); TGCT cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg08392591 chr16:89556376 ANKRD11 0.6 5.71 0.46 8.03e-8 Multiple myeloma (IgH translocation); TGCT cis rs11690935 0.959 rs7604918 chr2:172588094 G/A cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs11190604 1.000 rs2495759 chr10:102320363 C/T cg23241863 chr10:102295624 HIF1AN 0.62 4.76 0.39 5.38e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2456568 0.867 rs2456569 chr11:93691393 C/A cg14065697 chr11:93583672 C11orf90 -0.38 -4.68 -0.39 7.41e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg11890956 chr21:40555474 PSMG1 1.14 12.22 0.74 4.93e-23 Cognitive function; TGCT cis rs815815 0.583 rs878665 chr2:47403129 G/T cg27223769 chr2:47403360 CALM2 -0.53 -4.6 -0.38 1.01e-5 Dialysis-related mortality; TGCT cis rs17253792 0.822 rs10137364 chr14:56059987 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT trans rs10203711 1.000 rs6731675 chr2:239566943 T/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6427499 0.563 rs11265297 chr1:159890459 A/G cg15641364 chr1:159892206 TAGLN2 -0.28 -4.85 -0.4 3.6e-6 Platelet distribution width; TGCT cis rs6684514 1.000 rs12027741 chr1:156248148 T/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg07424592 chr7:64974309 NA -1.33 -7.99 -0.58 7.81e-13 Diabetic kidney disease; TGCT cis rs9486719 1.000 rs2472897 chr6:96870569 G/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs1801251 0.727 rs283482 chr2:233646920 A/T cg08000102 chr2:233561755 GIGYF2 0.66 7.42 0.55 1.6e-11 Coronary artery disease; TGCT cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs6087990 0.806 rs2424918 chr20:31382770 C/T cg13636640 chr20:31349939 DNMT3B 1.08 15.49 0.81 8.74e-31 Ulcerative colitis; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs8180040 1.000 rs4858888 chr3:47405305 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.46 -0.6 6.33e-14 Colorectal cancer; TGCT cis rs13191362 1.000 rs71567659 chr6:163001736 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2439831 0.867 rs2278860 chr15:43659046 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.86 -6.45 -0.5 2.3e-9 Lung cancer in ever smokers; TGCT cis rs2404602 0.647 rs12898416 chr15:77042292 C/G cg22467129 chr15:76604101 ETFA 0.47 4.58 0.38 1.13e-5 Blood metabolite levels; TGCT cis rs986417 0.901 rs1950316 chr14:61018305 T/C cg27398547 chr14:60952738 C14orf39 1.49 10.43 0.68 1.12e-18 Gut microbiota (bacterial taxa); TGCT cis rs7772486 0.597 rs6912351 chr6:146264071 T/C cg13319975 chr6:146136371 FBXO30 0.63 5.67 0.45 9.51e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7582180 0.585 rs6736311 chr2:100950599 C/G cg14675211 chr2:100938903 LONRF2 0.53 5.16 0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs1843834 0.755 rs10192196 chr2:225577135 C/T cg22455342 chr2:225449267 CUL3 0.63 6.12 0.48 1.16e-8 IgE levels in asthmatics (D.p. specific); TGCT cis rs57221529 0.766 rs56350081 chr5:583198 G/A cg09021430 chr5:549028 NA -0.37 -4.98 -0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7119 0.651 rs12902898 chr15:77849191 A/G cg27398640 chr15:77910606 LINGO1 -0.26 -5.08 -0.41 1.36e-6 Type 2 diabetes; TGCT cis rs9296092 0.517 rs76361685 chr6:33536458 G/C cg13560919 chr6:33536144 NA -0.23 -4.95 -0.41 2.4e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6499255 0.638 rs57824734 chr16:69811995 C/T cg15192750 chr16:69999425 NA 0.48 5.01 0.41 1.85e-6 IgE levels; TGCT cis rs6570726 0.902 rs9390326 chr6:145791222 A/G cg23711669 chr6:146136114 FBXO30 -0.68 -6.24 -0.49 6.2e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.56 4.97 0.41 2.19e-6 Height; TGCT cis rs1113500 0.509 rs1619485 chr1:108608347 T/C cg22161131 chr1:109420278 GPSM2 -0.5 -4.49 -0.37 1.61e-5 Growth-regulated protein alpha levels; TGCT cis rs881375 0.900 rs2241003 chr9:123666777 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.76 0.46 6.25e-8 Rheumatoid arthritis; TGCT cis rs6504340 0.793 rs12946855 chr17:46608030 G/A cg25032089 chr17:46643351 HOXB3 0.57 5.84 0.46 4.27e-8 Primary tooth development (number of teeth); TGCT cis rs7833790 0.654 rs7835342 chr8:82698092 A/G cg17211192 chr8:82754475 SNX16 -0.84 -7.67 -0.57 4.24e-12 Diastolic blood pressure; TGCT cis rs2153535 0.580 rs1932276 chr6:8442593 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs892961 0.932 rs7208671 chr17:75413129 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs875971 0.862 rs1981799 chr7:65955559 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs7714584 1.000 rs12652003 chr5:150231945 T/C cg22134413 chr5:150180641 NA 1.1 7.95 0.58 1e-12 Crohn's disease; TGCT cis rs1538970 0.962 rs2153607 chr1:45813820 G/A cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs739496 0.615 rs7977828 chr12:112094766 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs7607369 0.596 rs56304256 chr2:219276138 T/C cg02176678 chr2:219576539 TTLL4 -0.49 -6.24 -0.49 6.26e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs3749237 0.964 rs13084243 chr3:49821878 G/C cg07636037 chr3:49044803 WDR6 0.61 5.32 0.43 4.68e-7 Resting heart rate; TGCT cis rs9611565 0.559 rs12483860 chr22:41961916 C/T cg06634786 chr22:41940651 POLR3H -0.88 -8.25 -0.6 1.98e-13 Vitiligo; TGCT cis rs4319547 1.000 rs7309390 chr12:123110422 A/G cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.35 -0.43 4.1e-7 Body mass index; TGCT cis rs826838 0.900 rs1403523 chr12:39130570 T/A cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs8032315 0.965 rs4932373 chr15:91429287 A/C cg05211768 chr15:91427848 FES 0.49 4.89 0.4 3.02e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs11677416 0.885 rs4849119 chr2:113523463 G/C cg27083787 chr2:113543245 IL1A 0.17 4.46 0.37 1.83e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.29 -0.43 5.34e-7 Developmental language disorder (linguistic errors); TGCT cis rs3733585 0.660 rs13122290 chr4:9933832 A/G cg11266682 chr4:10021025 SLC2A9 -0.57 -7.3 -0.55 3.08e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs5769765 0.704 rs138837 chr22:50180714 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.32 4.59 0.38 1.09e-5 Schizophrenia; TGCT cis rs801193 1.000 rs7788576 chr7:66148302 G/A cg18876405 chr7:65276391 NA -0.35 -5.2 -0.42 7.81e-7 Aortic root size; TGCT cis rs6460942 0.908 rs73677570 chr7:12280329 T/C cg06484146 chr7:12443880 VWDE -0.53 -4.65 -0.39 8.3e-6 Coronary artery disease; TGCT cis rs533581 0.866 rs502258 chr16:88968547 G/A cg16701003 chr16:89028210 CBFA2T3 0.39 5.15 0.42 9.84e-7 Social autistic-like traits; TGCT cis rs4665809 0.878 rs4665826 chr2:26367503 A/T cg04944784 chr2:26401820 FAM59B 0.69 6.18 0.49 8.53e-9 Gut microbiome composition (summer); TGCT cis rs4727027 0.899 rs6464942 chr7:148826368 T/C cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg02782426 chr3:40428986 ENTPD3 0.39 4.47 0.37 1.77e-5 Renal cell carcinoma; TGCT cis rs4972806 0.849 rs2071581 chr2:177026148 G/T cg03152288 chr2:177042942 NA 0.61 5.16 0.42 9.51e-7 IgG glycosylation; TGCT cis rs7914558 1.000 rs11191541 chr10:104824199 A/G cg04362960 chr10:104952993 NT5C2 0.59 5.28 0.43 5.56e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9787249 1.000 rs9787249 chr1:40212878 G/A cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs478304 0.651 rs11227279 chr11:65495211 G/A cg10518572 chr11:65560635 OVOL1 -0.23 -4.45 -0.37 1.91e-5 Acne (severe); TGCT cis rs10791097 0.694 rs4937581 chr11:130740335 T/C cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3862260 0.509 rs12076924 chr1:120165826 C/T cg11530693 chr1:120165357 ZNF697 0.21 4.63 0.38 9.07e-6 Systemic lupus erythematosus; TGCT cis rs4819052 1.000 rs13047688 chr21:46669290 G/A cg06618935 chr21:46677482 NA -0.36 -4.82 -0.4 4.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10089 1.000 rs72794392 chr5:127490061 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.85 8.09 0.59 4.71e-13 Ileal carcinoids; TGCT cis rs7552404 1.000 rs12091720 chr1:76186949 G/A cg10523679 chr1:76189770 ACADM 0.9 9.73 0.66 5.57e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1371867 0.846 rs2047249 chr8:101234126 A/G cg06002616 chr8:101225028 SPAG1 0.48 5.2 0.42 8.15e-7 Atrioventricular conduction; TGCT cis rs704 0.726 rs2073867 chr17:26678960 G/C cg10342447 chr17:26645325 TMEM97 -0.55 -5.2 -0.42 7.94e-7 Osteoprotegerin levels; TGCT cis rs11105298 0.891 rs10777185 chr12:89921275 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs12765878 0.967 rs34887477 chr10:105643436 C/T cg11005552 chr10:105648138 OBFC1 0.44 7.6 0.56 6.24e-12 Coronary artery disease; TGCT cis rs12458462 0.892 rs3786228 chr18:77464170 C/T cg11879182 chr18:77439856 CTDP1 -0.71 -8.43 -0.6 7.53e-14 Monocyte count; TGCT cis rs10464366 0.746 rs6945547 chr7:39145389 C/G cg15212455 chr7:39170539 POU6F2 0.26 5.63 0.45 1.15e-7 IgG glycosylation; TGCT cis rs17253792 0.822 rs76164147 chr14:56140369 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs9388451 0.839 rs3799709 chr6:126078361 A/G cg05901451 chr6:126070800 HEY2 -1.02 -15.34 -0.81 2e-30 Brugada syndrome; TGCT cis rs6977660 0.714 rs2390156 chr7:19786138 A/T cg07541023 chr7:19748670 TWISTNB 0.81 4.46 0.37 1.81e-5 Thyroid stimulating hormone; TGCT cis rs35306767 0.903 rs11253493 chr10:936931 T/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs9902453 0.967 rs55744550 chr17:28475729 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg03396347 chr1:1875803 NA 0.34 5.72 0.46 7.58e-8 Body mass index; TGCT cis rs751728 0.664 rs12196293 chr6:33749151 A/G cg13859433 chr6:33739653 LEMD2 -0.32 -5.64 -0.45 1.1e-7 Crohn's disease; TGCT cis rs9556958 0.527 rs9517313 chr13:99105892 C/G cg07423050 chr13:99094983 FARP1 0.33 7.07 0.54 9.78e-11 Educational attainment (years of education); TGCT cis rs35306767 0.903 rs12254002 chr10:929133 A/G cg26597838 chr10:835615 NA -0.7 -9.58 -0.65 1.3e-16 Eosinophil percentage of granulocytes; TGCT trans rs3808502 0.647 rs7821302 chr8:11236572 T/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Neuroticism; TGCT trans rs7618501 0.633 rs4688757 chr3:50035323 T/C cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.6e-16 Intelligence (multi-trait analysis); TGCT cis rs55823223 0.564 rs9894009 chr17:73850414 C/T cg10935138 chr17:73851978 WBP2 0.82 7.59 0.56 6.81e-12 Psoriasis; TGCT cis rs9858542 1.000 rs3197999 chr3:49721532 G/A cg03060546 chr3:49711283 APEH -0.69 -5.87 -0.47 3.67e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1153858 1.000 rs4775906 chr15:45638294 C/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2180341 1.000 rs7776136 chr6:127638348 A/T cg24812749 chr6:127587940 RNF146 0.94 7.43 0.55 1.56e-11 Breast cancer; TGCT cis rs651907 0.557 rs3806654 chr3:101396529 G/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.24 0.43 6.66e-7 Colorectal cancer; TGCT cis rs319204 0.877 rs319172 chr5:146288339 G/T cg25021259 chr5:146258546 PPP2R2B 0.35 4.53 0.38 1.39e-5 Schizophrenia; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs6674176 0.542 rs2906468 chr1:44319007 A/G cg12908607 chr1:44402522 ARTN -0.63 -7.18 -0.54 5.58e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs2033711 0.840 rs10423138 chr19:58928302 T/C cg13877915 chr19:58951672 ZNF132 0.89 11.13 0.71 2.22e-20 Uric acid clearance; TGCT cis rs35771425 0.619 rs7538812 chr1:211442186 A/G cg25617285 chr1:211431773 RCOR3 -0.5 -5.88 -0.47 3.63e-8 Educational attainment (years of education); TGCT cis rs2115630 0.967 rs10438428 chr15:85330745 C/T cg17173187 chr15:85201210 NMB -0.38 -4.75 -0.39 5.52e-6 P wave terminal force; TGCT cis rs17741873 0.779 rs2242255 chr10:75597289 T/A cg07699608 chr10:75541558 CHCHD1 0.72 5.15 0.42 1.02e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs1799949 1.000 rs11659028 chr17:41195025 T/A cg10047753 chr17:41438598 NA 0.88 7.8 0.57 2.22e-12 Menopause (age at onset); TGCT cis rs12935418 0.616 rs11863536 chr16:80969674 C/T cg07676361 chr16:80966860 NA -0.35 -4.69 -0.39 6.99e-6 Mean corpuscular volume; TGCT cis rs4930561 0.690 rs6591334 chr11:67924559 A/G cg04465784 chr11:67976953 SUV420H1 -0.4 -5.37 -0.43 3.72e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs2354432 1.000 rs11239944 chr1:146691015 C/T cg25205988 chr1:146714368 CHD1L 0.94 7.15 0.54 6.76e-11 Mitochondrial DNA levels; TGCT cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs1385374 0.858 rs10773578 chr12:129290026 G/C cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs11105298 0.891 rs10858898 chr12:89922111 A/G cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs447921 0.861 rs66686654 chr17:74430310 A/T cg09812376 chr17:74270190 QRICH2 -0.48 -4.71 -0.39 6.4e-6 Mitochondrial DNA levels; TGCT cis rs7681440 0.904 rs10004413 chr4:90769479 T/C cg20003494 chr4:90757398 SNCA -0.6 -5.76 -0.46 6.3e-8 Dementia with Lewy bodies; TGCT cis rs739496 0.843 rs616668 chr12:111974280 T/G cg10833066 chr12:111807467 FAM109A 0.37 4.93 0.4 2.61e-6 Platelet count; TGCT trans rs7613875 0.600 rs2856238 chr3:50158191 C/T cg21659725 chr3:3221576 CRBN 0.69 7.57 0.56 7.35e-12 Body mass index; TGCT cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs4689388 0.926 rs10937720 chr4:6295451 A/G cg14416269 chr4:6271139 WFS1 0.37 4.85 0.4 3.58e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7582180 0.676 rs4264577 chr2:100930662 T/C cg14675211 chr2:100938903 LONRF2 0.53 5.24 0.43 6.82e-7 Intelligence (multi-trait analysis); TGCT cis rs737008 0.922 rs1559394 chr16:11369205 A/G cg00044050 chr16:11439710 C16orf75 -0.71 -7.21 -0.54 4.91e-11 Obesity-related traits; TGCT cis rs1729951 0.575 rs16844325 chr3:136678161 C/G cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs926938 0.967 rs11587596 chr1:115241857 A/G cg12756093 chr1:115239321 AMPD1 -0.48 -6.99 -0.53 1.51e-10 Autism; TGCT cis rs6089584 0.854 rs6061407 chr20:60622048 A/C cg13665807 chr20:60559372 TAF4 -0.46 -4.9 -0.4 2.87e-6 Body mass index; TGCT cis rs12701220 0.948 rs12690826 chr7:1081618 A/G cg07217954 chr7:1067459 C7orf50 -0.48 -4.7 -0.39 6.77e-6 Bronchopulmonary dysplasia; TGCT cis rs11122272 0.735 rs2250734 chr1:231485958 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.37e-11 Hemoglobin concentration; TGCT cis rs3806843 0.741 rs2563293 chr5:140110536 T/C cg19875535 chr5:140030758 IK -0.37 -6.19 -0.49 7.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6912958 1.000 rs9294379 chr6:88152535 C/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.74 -0.39 5.79e-6 Monocyte percentage of white cells; TGCT cis rs2404602 1.000 rs2404602 chr15:77030792 A/G cg26408565 chr15:76604113 ETFA -0.42 -5.48 -0.44 2.31e-7 Blood metabolite levels; TGCT cis rs7781977 0.575 rs7782210 chr7:50348745 A/G cg01139861 chr7:50343298 IKZF1 0.5 5.9 0.47 3.17e-8 IgG glycosylation; TGCT cis rs7726839 0.540 rs12517638 chr5:645484 C/T cg20362242 chr5:692897 TPPP 0.5 4.57 0.38 1.17e-5 Obesity-related traits; TGCT cis rs748404 0.660 rs690472 chr15:43764368 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.77 0.39 5.05e-6 Lung cancer; TGCT trans rs7618501 0.633 rs2856234 chr3:50139142 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT trans rs1864729 0.901 rs2451114 chr8:98273762 G/A cg08679828 chr8:102218111 ZNF706 -1.01 -7.04 -0.53 1.17e-10 Estradiol plasma levels (breast cancer); TGCT cis rs1348850 0.914 rs2060929 chr2:178280031 T/C cg22681709 chr2:178499509 PDE11A -0.34 -4.47 -0.37 1.74e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs10791323 0.569 rs329664 chr11:133754975 G/T cg03690763 chr11:133734501 NA -0.31 -5.33 -0.43 4.52e-7 Childhood ear infection; TGCT cis rs7611238 0.560 rs7652612 chr3:195025186 A/T cg27323046 chr3:195102265 ACAP2 0.36 4.8 0.4 4.41e-6 Body mass index; TGCT cis rs2299587 0.527 rs7843715 chr8:17733526 C/A cg01800426 chr8:17659068 MTUS1 -0.54 -4.85 -0.4 3.69e-6 Economic and political preferences; TGCT cis rs3749237 0.576 rs62259939 chr3:49386047 G/A cg03060546 chr3:49711283 APEH 0.76 8.63 0.61 2.46e-14 Resting heart rate; TGCT cis rs1045529 0.524 rs34251783 chr8:8891376 T/C cg06636001 chr8:8085503 FLJ10661 -0.66 -5.58 -0.45 1.42e-7 Myopia;Myopia (pathological); TGCT cis rs317865 0.737 rs73234651 chr4:16196651 G/A cg04764131 chr4:16228633 TAPT1;FLJ39653 0.78 5.11 0.42 1.18e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs2836950 0.805 rs2836961 chr21:40627020 A/C cg11890956 chr21:40555474 PSMG1 -0.63 -5.98 -0.47 2.26e-8 Menarche (age at onset); TGCT trans rs1005277 0.603 rs1998062 chr10:38457652 G/C cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.5e-21 Extrinsic epigenetic age acceleration; TGCT cis rs8103278 0.507 rs10422883 chr19:46247641 A/G cg14061069 chr19:46274453 DMPK 0.62 10.19 0.68 4.35e-18 Coronary artery disease; TGCT cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg12310025 chr6:25882481 NA 0.51 5.26 0.43 6.01e-7 Blood metabolite levels; TGCT cis rs2677744 0.534 rs6496739 chr15:91494430 C/T cg01710897 chr15:91497902 RCCD1 0.36 5.08 0.42 1.33e-6 Attention deficit hyperactivity disorder; TGCT cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.58e-9 Gut microbiome composition (summer); TGCT cis rs669446 0.561 rs664336 chr1:44101800 A/G cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.88 9.42 0.65 3.23e-16 Platelet count; TGCT trans rs561341 1.000 rs8077092 chr17:30281992 T/C cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs459571 0.920 rs417142 chr9:136891370 G/T cg13789015 chr9:136890014 NCRNA00094 0.4 7.27 0.55 3.55e-11 Platelet distribution width; TGCT cis rs6840360 0.642 rs6855845 chr4:152417380 A/G cg17479576 chr4:152424074 FAM160A1 -0.57 -6.02 -0.48 1.85e-8 Intelligence (multi-trait analysis); TGCT cis rs2688608 0.620 rs7076525 chr10:75512797 C/T cg15838173 chr10:75533400 FUT11 -0.3 -5.02 -0.41 1.76e-6 Inflammatory bowel disease; TGCT cis rs826838 1.000 rs10880826 chr12:38672787 G/C cg13010199 chr12:38710504 ALG10B 0.77 6.31 0.49 4.59e-9 Heart rate; TGCT cis rs9911578 1.000 rs4398153 chr17:56968181 T/C cg05425664 chr17:57184151 TRIM37 0.62 6.18 0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs3087591 0.960 rs2905803 chr17:29520056 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 7.39 0.55 1.91e-11 Hip circumference; TGCT cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 7.8 0.57 2.16e-12 Platelet count; TGCT cis rs11677370 0.561 rs11687254 chr2:3830906 C/T cg17052675 chr2:3827356 NA -0.44 -7.23 -0.54 4.4e-11 Type 2 diabetes; TGCT cis rs7542091 0.704 rs1108628 chr1:210041150 A/G cg00989853 chr1:209979345 IRF6 0.42 4.44 0.37 1.97e-5 Monobrow; TGCT cis rs651907 0.557 rs13077925 chr3:101488181 T/A cg11279151 chr3:101281821 RG9MTD1 -0.32 -6.74 -0.52 5.44e-10 Colorectal cancer; TGCT cis rs4700695 0.841 rs706680 chr5:65317338 T/C cg21114390 chr5:65439923 SFRS12 0.6 4.47 0.37 1.74e-5 Facial morphology (factor 19); TGCT trans rs10802346 0.545 rs1361408 chr1:246410054 T/G cg13514129 chr1:39547527 MACF1 1.03 9.45 0.65 2.71e-16 Fractional exhaled nitric oxide (childhood); TGCT cis rs10504229 1.000 rs68114352 chr8:58196081 C/T cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs9517320 0.534 rs61971163 chr13:99188883 G/A cg07423050 chr13:99094983 FARP1 -0.28 -5.53 -0.44 1.83e-7 Longevity; TGCT cis rs7772486 0.686 rs702305 chr6:145973840 A/G cg05347473 chr6:146136440 FBXO30 -0.47 -4.45 -0.37 1.9e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs910316 1.000 rs910316 chr14:75626042 A/C cg11812906 chr14:75593930 NEK9 0.75 7.44 0.56 1.43e-11 Height; TGCT cis rs12188164 0.930 rs11743825 chr5:475463 C/T cg21144161 chr5:423903 AHRR 0.25 4.65 0.39 8.21e-6 Cystic fibrosis severity; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg11905131 chr22:24372483 LOC391322 -0.85 -9.56 -0.65 1.49e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs77741769 0.529 rs10849791 chr12:121235280 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.46 0.37 1.83e-5 Mean corpuscular volume; TGCT cis rs7208859 0.623 rs11656844 chr17:29060597 G/T cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4304924 0.500 rs9601109 chr13:79220114 A/G cg01819759 chr13:79234251 RNF219 0.86 7.64 0.57 5.22e-12 Large artery stroke; TGCT cis rs12136530 0.554 rs4912093 chr1:19762321 T/C cg18923740 chr1:19971790 NBL1 0.35 4.57 0.38 1.16e-5 Lead levels in blood; TGCT cis rs992157 0.835 rs10932768 chr2:219146199 T/A cg00012203 chr2:219082015 ARPC2 -0.8 -7.9 -0.58 1.31e-12 Colorectal cancer; TGCT cis rs911263 0.961 rs2104047 chr14:68754417 T/C cg18825221 chr14:68749962 RAD51L1 0.28 5.57 0.45 1.52e-7 Primary biliary cholangitis; TGCT cis rs1943345 0.686 rs10898088 chr11:82874970 G/A cg07047830 chr11:82868014 PCF11 0.53 5.42 0.44 3e-7 Obesity-related traits; TGCT cis rs9611519 0.732 rs1883826 chr22:41703428 G/A cg06634786 chr22:41940651 POLR3H -0.61 -5.53 -0.44 1.8e-7 Neuroticism; TGCT cis rs2663905 0.706 rs7162859 chr15:81360038 C/T cg05624577 chr15:81411055 NA 0.55 4.67 0.39 7.64e-6 QT interval (drug interaction); TGCT cis rs9916302 0.904 rs9894500 chr17:37515735 G/C cg15445000 chr17:37608096 MED1 -0.35 -5.08 -0.42 1.33e-6 Glomerular filtration rate (creatinine); TGCT cis rs10883723 0.962 rs1056740 chr10:104236552 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 7.52 0.56 9.74e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs112591243 0.570 rs2839340 chr21:47989804 C/T cg10657630 chr21:48055338 PRMT2 1.0 5.07 0.41 1.43e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs933688 0.941 rs2887007 chr5:90740531 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.11 10.58 0.69 4.97e-19 Smoking behavior; TGCT cis rs6570726 0.846 rs409553 chr6:145886963 C/T cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs3806843 0.735 rs813897 chr5:140070029 T/C cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs748404 0.676 rs4401024 chr15:43650335 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs6141769 0.542 rs6058840 chr20:31319116 A/T cg13636640 chr20:31349939 DNMT3B 0.52 4.55 0.38 1.26e-5 Subjective well-being; TGCT cis rs916888 0.610 rs199446 chr17:44813169 G/A cg17911788 chr17:44343683 NA 0.48 5.67 0.45 9.45e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2342371 0.816 rs11707744 chr3:196213855 C/G cg15048948 chr3:196158458 UBXN7 -0.53 -4.57 -0.38 1.18e-5 Fat distribution (HIV); TGCT trans rs10203711 1.000 rs907103 chr2:239564541 A/G cg16021909 chr1:248021091 TRIM58 -0.66 -6.64 -0.51 8.68e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs26868 0.816 rs26873 chr16:2247362 C/T cg25665528 chr16:2260870 C16orf79 -0.3 -4.67 -0.39 7.73e-6 Height; TGCT cis rs3008870 0.959 rs2985826 chr1:67412918 G/C cg03991309 chr1:68237761 GNG12 0.27 4.57 0.38 1.18e-5 Lymphocyte percentage of white cells; TGCT cis rs1042058 0.565 rs650110 chr10:30753132 A/G cg13289132 chr10:30722225 MAP3K8 -0.4 -4.75 -0.39 5.6e-6 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs6598955 0.671 rs59143843 chr1:26641595 G/T cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs3617 0.539 rs9825369 chr3:52953311 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.46 4.6 0.38 1.03e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4851266 1.000 rs4583487 chr2:100837126 G/T cg07810366 chr2:100720526 AFF3 -0.37 -5.33 -0.43 4.53e-7 Educational attainment; TGCT trans rs208520 0.690 rs866452 chr6:66849936 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -10.32 -0.68 2.16e-18 Exhaled nitric oxide output; TGCT cis rs9364220 1.000 rs9364220 chr6:168490568 G/A cg02770688 chr6:168491649 NA -0.29 -4.86 -0.4 3.52e-6 Attention deficit hyperactivity disorder (inattention symptoms);Attention deficit hyperactivity disorder (combined symptoms); TGCT cis rs2688608 0.592 rs3933085 chr10:75483331 C/T cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs66561647 0.634 rs7821856 chr8:128939499 A/G cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.52 0.38 1.43e-5 Hemoglobin concentration; TGCT cis rs12935418 0.583 rs7186230 chr16:80964620 A/G cg07676361 chr16:80966860 NA -0.36 -4.73 -0.39 6.04e-6 Mean corpuscular volume; TGCT cis rs11031096 0.782 rs11031110 chr11:4162652 G/C cg18678763 chr11:4115507 RRM1 -0.52 -6.66 -0.51 7.83e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4803468 0.967 rs67047091 chr19:41938684 C/T cg09537434 chr19:41945824 ATP5SL 0.91 10.05 0.67 9.48e-18 Height; TGCT cis rs7772486 0.790 rs1133832 chr6:146205604 C/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.74 -0.39 5.79e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.659 rs34382037 chr17:56643550 G/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs7666738 0.830 rs3852122 chr4:98697400 T/C cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2594989 0.831 rs9840982 chr3:11564940 C/A cg00170343 chr3:11313890 ATG7 -0.66 -4.9 -0.4 2.95e-6 Circulating chemerin levels; TGCT cis rs6845621 0.700 rs10008431 chr4:18934125 T/C cg12196642 chr4:18937545 NA -0.25 -4.47 -0.37 1.78e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs9914544 0.762 rs4322727 chr17:18798573 A/T cg26306683 chr17:18585705 ZNF286B -0.55 -5.02 -0.41 1.78e-6 Educational attainment (years of education); TGCT cis rs2153535 0.580 rs4960413 chr6:8438466 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg02953382 chr22:24373134 LOC391322 -0.78 -8.12 -0.59 4.06e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs112591243 0.570 rs77436553 chr21:47759343 G/A cg10657630 chr21:48055338 PRMT2 1.11 5.44 0.44 2.75e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg21237687 chr17:6899380 ALOX12 -0.53 -5.69 -0.46 8.5e-8 Tonsillectomy; TGCT cis rs7937612 1.000 rs7951250 chr11:120309036 A/G cg24566217 chr11:120254723 ARHGEF12 -0.31 -5.19 -0.42 8.16e-7 Intraocular pressure; TGCT cis rs9467711 0.606 rs9393712 chr6:26371000 G/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2439831 1.000 rs2245054 chr15:43751909 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.18 0.59 2.83e-13 Lung cancer in ever smokers; TGCT cis rs3772130 0.583 rs4296627 chr3:121567684 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.59 5.43 0.44 2.8e-7 Cognitive performance; TGCT cis rs35146811 0.586 rs34213597 chr7:99591021 C/T cg13334819 chr7:99746414 C7orf59 -0.61 -5.29 -0.43 5.32e-7 Coronary artery disease; TGCT cis rs4886920 0.573 rs34709918 chr15:78104683 A/G cg25212270 chr15:78015279 NA -0.24 -4.54 -0.38 1.34e-5 Neuroticism; TGCT cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg02487422 chr3:49467188 NICN1 -0.54 -5.05 -0.41 1.51e-6 Menarche (age at onset); TGCT cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 4.92 0.4 2.72e-6 Bipolar disorder; TGCT cis rs11190604 0.790 rs11190535 chr10:102197441 A/T cg23241863 chr10:102295624 HIF1AN 0.64 4.8 0.4 4.42e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2439831 0.867 rs2255051 chr15:43846161 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.97 7.38 0.55 2.03e-11 Lung cancer in ever smokers; TGCT cis rs7412746 0.563 rs3768013 chr1:150815411 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.61e-6 Melanoma; TGCT cis rs9796 0.870 rs4923890 chr15:41258990 T/C cg18705301 chr15:41695430 NDUFAF1 0.43 5.63 0.45 1.13e-7 Menopause (age at onset); TGCT cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg21724239 chr8:58056113 NA 0.39 5.08 0.41 1.37e-6 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.519 rs3913237 chr11:49551828 G/A cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Height; TGCT cis rs7568458 0.783 rs2166529 chr2:85742175 A/C cg17127132 chr2:85788382 GGCX -0.63 -5.51 -0.44 1.99e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3862435 0.518 rs2601189 chr15:90929874 G/A cg14166756 chr15:90894880 ZNF774 -0.33 -5.32 -0.43 4.59e-7 Response to exercise (triglyceride level interaction); TGCT cis rs4808199 1.000 rs60003758 chr19:19557353 A/G cg03709012 chr19:19516395 GATAD2A 0.97 7.52 0.56 9.52e-12 Nonalcoholic fatty liver disease; TGCT cis rs7617773 0.780 rs34589064 chr3:48339549 G/A cg11946769 chr3:48343235 NME6 0.82 7.06 0.54 1.03e-10 Coronary artery disease; TGCT cis rs1395 0.744 rs4665962 chr2:27515105 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 8.02 0.58 6.76e-13 Blood metabolite levels; TGCT cis rs7818688 0.697 rs76631135 chr8:95980988 G/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg07507251 chr3:52567010 NT5DC2 0.42 5.92 0.47 2.94e-8 Bipolar disorder; TGCT cis rs10197940 0.662 rs10175134 chr2:152299355 G/A cg19508488 chr2:152266495 RIF1 0.72 6.56 0.51 1.31e-9 Lung cancer; TGCT cis rs514406 0.825 rs6588441 chr1:53223494 G/A cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.41 2.55e-6 Monocyte count; TGCT cis rs67311347 1.000 rs4974017 chr3:40473519 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs7582180 0.627 rs2241811 chr2:101011724 C/T cg14675211 chr2:100938903 LONRF2 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs4499344 0.633 rs166310 chr19:33155187 G/A cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg19318889 chr4:1322082 MAEA 0.28 6.78 0.52 4.46e-10 Longevity; TGCT cis rs4746818 1.000 rs10823301 chr10:70885875 G/A cg04149295 chr10:70884716 VPS26A 0.73 5.25 0.43 6.31e-7 Left atrial antero-posterior diameter; TGCT cis rs3806843 0.549 rs246012 chr5:140336277 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs931812 0.895 rs4734493 chr8:101902169 C/T cg20993868 chr7:22813445 NA -0.38 -8.58 -0.61 3.32e-14 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs7829975 0.688 rs13270194 chr8:8378102 T/C cg15556689 chr8:8085844 FLJ10661 0.68 6.37 0.5 3.33e-9 Mood instability; TGCT cis rs1218582 0.772 rs6686873 chr1:154913404 C/G cg24250549 chr1:154909240 PMVK 0.62 6.28 0.49 5.29e-9 Prostate cancer; TGCT cis rs3806843 0.521 rs246061 chr5:140324656 C/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs116095464 0.558 rs12173244 chr5:269524 G/A cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs12477438 0.520 rs4588238 chr2:99749350 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs9807989 1.000 rs9807989 chr2:102971200 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs12220898 0.679 rs12254955 chr10:50480763 T/G cg06072769 chr10:50146962 WDFY4 0.38 4.98 0.41 2.07e-6 Inflammatory biomarkers; TGCT trans rs877282 0.853 rs11596346 chr10:756673 A/T cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs10193935 0.901 rs9309082 chr2:42581412 A/G cg27598129 chr2:42591480 NA -0.42 -5.69 -0.46 8.5e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs1008375 1.000 rs28497813 chr4:17685503 A/G cg10189774 chr4:17578691 LAP3 0.52 4.74 0.39 5.82e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs208520 0.661 rs207111 chr6:66792513 C/T cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg17264618 chr3:40429014 ENTPD3 0.33 4.71 0.39 6.52e-6 Renal cell carcinoma; TGCT cis rs3008870 1.000 rs2755244 chr1:67484470 C/T cg08660285 chr1:67390436 MIER1;WDR78 -1.07 -10.97 -0.7 5.49e-20 Lymphocyte percentage of white cells; TGCT cis rs10751667 0.714 rs7933889 chr11:972270 C/T cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs1552244 0.882 rs36006511 chr3:10054191 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.43 -0.5 2.53e-9 Alzheimer's disease; TGCT cis rs7666738 0.962 rs2865991 chr4:99067369 C/A cg18180107 chr4:99064573 C4orf37 0.56 4.54 0.38 1.33e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2072499 1.000 rs2540173 chr1:156188214 A/G cg25208724 chr1:156163844 SLC25A44 1.08 15.41 0.81 1.37e-30 Testicular germ cell tumor; TGCT cis rs1729951 0.575 rs361244 chr3:136697506 C/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.62e-9 Neuroticism; TGCT cis rs7659604 0.540 rs11098643 chr4:122701507 C/A cg06713675 chr4:122721982 EXOSC9 0.36 4.52 0.38 1.45e-5 Type 2 diabetes; TGCT cis rs4924935 1.000 rs9905565 chr17:18758641 C/T cg26378065 chr17:18585709 ZNF286B 0.57 4.8 0.4 4.45e-6 Pancreatic cancer; TGCT cis rs9807989 0.839 rs4988957 chr2:102968075 C/T cg09003973 chr2:102972529 NA -0.64 -5.7 -0.46 8.28e-8 Asthma; TGCT cis rs7216064 1.000 rs62084246 chr17:65867911 G/C cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6089829 0.855 rs4809459 chr20:61661345 C/T cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT trans rs8073060 0.586 rs2626625 chr17:34027607 C/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs35306767 0.668 rs12356612 chr10:1055055 C/T cg26597838 chr10:835615 NA 0.57 6.58 0.51 1.21e-9 Eosinophil percentage of granulocytes; TGCT cis rs1997103 0.911 rs6945663 chr7:55407011 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs4906332 1.000 rs17617307 chr14:103904965 C/G cg26031613 chr14:104095156 KLC1 -0.53 -4.72 -0.39 6.2e-6 Coronary artery disease; TGCT cis rs42648 0.693 rs194533 chr7:89870777 A/G cg25739043 chr7:89950458 NA -0.54 -5.04 -0.41 1.64e-6 Homocysteine levels; TGCT cis rs2404602 0.647 rs11632765 chr15:76974261 A/T cg23625390 chr15:77176239 SCAPER 0.39 5.03 0.41 1.65e-6 Blood metabolite levels; TGCT cis rs9926296 0.609 rs4785709 chr16:89796665 G/A cg08627397 chr16:89984028 MC1R 0.31 4.98 0.41 2.05e-6 Vitiligo; TGCT cis rs981844 0.775 rs56101345 chr4:154764261 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.89 0.62 5.85e-15 Response to statins (LDL cholesterol change); TGCT cis rs7119038 0.818 rs57494551 chr11:118661398 C/T cg19308663 chr11:118741387 NA 0.32 6.21 0.49 7.32e-9 Sjögren's syndrome; TGCT cis rs7208859 0.623 rs55638872 chr17:29149552 G/C cg13385521 chr17:29058706 SUZ12P 0.81 4.85 0.4 3.68e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3849570 0.643 rs6548779 chr3:81968512 A/G cg07356753 chr3:81810745 GBE1 -0.67 -5.97 -0.47 2.3e-8 Waist circumference;Body mass index; TGCT cis rs514406 0.861 rs2448792 chr1:53268313 T/C cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg04389838 chr3:44770851 ZNF501 -0.35 -4.5 -0.37 1.57e-5 Depressive symptoms; TGCT cis rs12579753 1.000 rs11519754 chr12:82209181 A/T cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs992157 0.835 rs7585702 chr2:219146607 T/C cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT trans rs10504390 0.656 rs77264178 chr8:66515086 G/A cg18118147 chr19:51128640 SYT3 -0.77 -6.85 -0.52 2.99e-10 IgG glycosylation; TGCT cis rs78487399 0.808 rs7591387 chr2:43756032 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.02 -0.41 1.75e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs666930 1.000 rs666930 chr1:120258970 A/G cg19096424 chr1:120255104 PHGDH 0.54 5.06 0.41 1.46e-6 Breast cancer; TGCT cis rs4252435 0.614 rs8176036 chr7:142640596 T/G cg21621906 chr7:142494914 NA -1.08 -4.53 -0.38 1.36e-5 Cancer; TGCT cis rs7044106 0.791 rs747819 chr9:123488441 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 7.88 0.58 1.46e-12 Hip circumference adjusted for BMI; TGCT cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg05985448 chr10:134359359 INPP5A 0.21 4.63 0.38 9.16e-6 Migraine; TGCT cis rs637571 0.522 rs528736 chr11:65705108 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.62 6.32 0.49 4.22e-9 Eosinophil percentage of white cells; TGCT cis rs2738048 0.545 rs2738045 chr8:6823568 T/C cg24860332 chr8:6827800 DEFA10P -0.42 -6.08 -0.48 1.36e-8 IgA nephropathy; TGCT cis rs6831352 0.918 rs2602894 chr4:100045647 A/G cg12011299 chr4:100065546 ADH4 0.41 4.92 0.4 2.72e-6 Alcohol dependence; TGCT cis rs2836974 0.966 rs7283516 chr21:40690537 A/G cg11644478 chr21:40555479 PSMG1 0.97 9.14 0.63 1.54e-15 Cognitive function; TGCT cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs7926906 0.713 rs10741373 chr11:90520993 G/A cg26138821 chr11:89956704 CHORDC1 -0.44 -4.7 -0.39 6.81e-6 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.706 rs1874226 chr17:37729031 C/T cg03321784 chr17:37729644 NA -0.44 -4.58 -0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs2456568 0.548 rs4402256 chr11:93660803 T/C cg16099599 chr11:93583650 C11orf90 -0.38 -4.62 -0.38 9.53e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg04013166 chr16:89971882 TCF25 0.33 4.47 0.37 1.75e-5 Skin colour saturation; TGCT cis rs9914988 0.725 rs9905510 chr17:27092325 G/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7769051 0.614 rs6912936 chr6:133102664 A/G cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs12477438 1.000 rs12477438 chr2:99841085 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -6.36 -0.5 3.59e-9 Chronic sinus infection; TGCT cis rs2243480 1.000 rs1796228 chr7:66033084 G/A cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs910316 1.000 rs1043674 chr14:75549370 T/C cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs892961 1.000 rs2164449 chr17:75401190 G/A cg05865280 chr17:75406074 SEPT9 0.28 6.57 0.51 1.22e-9 Airflow obstruction; TGCT cis rs921968 0.613 rs2303565 chr2:219545309 T/C cg02176678 chr2:219576539 TTLL4 -0.33 -4.45 -0.37 1.91e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs9814567 1.000 rs13090969 chr3:134307257 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9556958 0.527 rs9517313 chr13:99105892 C/G cg20487152 chr13:99095054 FARP1 0.26 5.07 0.41 1.41e-6 Educational attainment (years of education); TGCT cis rs11190604 1.000 rs2489048 chr10:102348497 G/T cg23241863 chr10:102295624 HIF1AN 0.67 4.87 0.4 3.36e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9911578 0.967 rs3826353 chr17:57075299 C/T cg05425664 chr17:57184151 TRIM37 -0.65 -6.66 -0.51 7.92e-10 Intelligence (multi-trait analysis); TGCT cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.65 0.45 1.06e-7 Height; TGCT cis rs4253772 0.591 rs73886791 chr22:46687212 A/G cg24881330 chr22:46731750 TRMU 0.96 6.38 0.5 3.18e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs589448 0.933 rs523398 chr12:69752775 C/T cg11871910 chr12:69753446 YEATS4 0.87 10.07 0.67 8.72e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs10479542 0.806 rs4700835 chr5:178976313 A/G cg21226059 chr5:178986404 RUFY1 0.44 4.74 0.39 5.79e-6 Lung cancer; TGCT cis rs35306767 0.903 rs10508208 chr10:910983 C/T cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs2014572 0.967 rs4801452 chr19:57768066 A/G cg24459738 chr19:57751996 ZNF805 -0.58 -5.71 -0.46 7.75e-8 Hyperactive-impulsive symptoms; TGCT cis rs3749237 0.964 rs7431078 chr3:49808190 G/A cg03060546 chr3:49711283 APEH 0.72 7.38 0.55 2.02e-11 Resting heart rate; TGCT cis rs4700695 0.764 rs36299 chr5:65348120 G/T cg21114390 chr5:65439923 SFRS12 0.61 4.51 0.38 1.46e-5 Facial morphology (factor 19); TGCT cis rs10875746 0.903 rs11168420 chr12:48515896 C/T cg20731937 chr12:48336164 NA 0.61 5.01 0.41 1.81e-6 Longevity (90 years and older); TGCT cis rs9611565 0.568 rs5758441 chr22:42132888 C/A cg13695892 chr22:41940480 POLR3H 0.84 7.96 0.58 9.2e-13 Vitiligo; TGCT cis rs1538970 0.884 rs781232 chr1:45890399 C/T cg05343316 chr1:45956843 TESK2 -0.75 -6.08 -0.48 1.39e-8 Platelet count; TGCT cis rs13217239 0.646 rs7768407 chr6:27016795 G/A cg07220782 chr6:26987966 LOC100270746;C6orf41 0.44 4.95 0.41 2.39e-6 Schizophrenia; TGCT trans rs916888 0.647 rs199523 chr17:44848517 C/A cg22433210 chr17:43662623 NA -0.92 -7.55 -0.56 8e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs72945132 0.882 rs67283107 chr11:70221204 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.39 0.55 1.94e-11 Coronary artery disease; TGCT cis rs3741404 0.825 rs2515241 chr11:63975331 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.9 10.32 0.68 2.07e-18 Platelet count; TGCT cis rs10507380 0.824 rs117253068 chr13:27925061 C/T cg25543773 chr13:27185723 WASF3 0.32 4.52 0.38 1.45e-5 Electrocardiographic traits; TGCT cis rs459571 0.959 rs460888 chr9:136913123 C/G cg13789015 chr9:136890014 NCRNA00094 0.4 7.15 0.54 6.64e-11 Platelet distribution width; TGCT cis rs67133203 0.632 rs706802 chr12:51373742 C/T cg01517968 chr12:52348879 ACVR1B -0.38 -4.91 -0.4 2.81e-6 Urinary tract infection frequency; TGCT cis rs12765878 0.934 rs58543155 chr10:105643244 G/A cg11005552 chr10:105648138 OBFC1 0.44 7.6 0.56 6.24e-12 Coronary artery disease; TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg07092213 chr7:1199455 ZFAND2A -0.49 -5.62 -0.45 1.2e-7 Longevity;Endometriosis; TGCT cis rs7666738 0.830 rs1426663 chr4:98990092 T/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1629083 0.935 rs2051480 chr11:118094513 A/G cg16594165 chr11:118135105 MPZL2 -0.33 -4.7 -0.39 6.73e-6 Lung cancer; TGCT cis rs3733585 0.605 rs4235355 chr4:10123078 C/A cg11266682 chr4:10021025 SLC2A9 -0.55 -6.43 -0.5 2.44e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs13191362 1.000 rs13220181 chr6:163004401 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28595532 0.920 rs6818519 chr4:119787820 G/T cg00700008 chr4:120138107 USP53 0.49 4.48 0.37 1.71e-5 Cannabis dependence symptom count; TGCT cis rs3806843 0.546 rs246023 chr5:140333990 G/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs9300255 0.602 rs2851435 chr12:123712416 G/A cg00376283 chr12:123451042 ABCB9 0.73 5.07 0.41 1.42e-6 Neutrophil percentage of white cells; TGCT cis rs6088580 0.634 rs3746455 chr20:32957216 G/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.8 -0.4 4.5e-6 Glomerular filtration rate (creatinine); TGCT cis rs7524258 0.868 rs2412152 chr1:7303213 C/T cg07173049 chr1:7289937 CAMTA1 0.29 4.82 0.4 4.2e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs2235642 1.000 rs2235642 chr16:1584866 T/C cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.82 -0.4 4.09e-6 Coronary artery disease; TGCT cis rs854765 0.547 rs2955370 chr17:17966945 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.28 -0.6 1.68e-13 Total body bone mineral density; TGCT cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17376456 1.000 rs34068652 chr5:93563319 G/A cg25358565 chr5:93447407 FAM172A 0.95 7.18 0.54 5.63e-11 Diabetic retinopathy; TGCT cis rs9309473 0.607 rs7574291 chr2:73594941 A/G cg20560298 chr2:73613845 ALMS1 -0.41 -4.56 -0.38 1.23e-5 Metabolite levels; TGCT cis rs5750830 0.594 rs5757647 chr22:39775047 C/A cg01416388 chr22:39784598 NA -0.59 -5.8 -0.46 5.09e-8 Intelligence (multi-trait analysis); TGCT cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg20887711 chr4:1340912 KIAA1530 0.91 8.34 0.6 1.22e-13 Longevity; TGCT cis rs2115630 0.645 rs1107179 chr15:85198362 A/C cg12863693 chr15:85201151 NMB 0.4 5.31 0.43 4.85e-7 P wave terminal force; TGCT cis rs453301 0.653 rs7005133 chr8:8901222 T/G cg08975724 chr8:8085496 FLJ10661 0.58 4.95 0.41 2.33e-6 Joint mobility (Beighton score); TGCT cis rs11190604 1.000 rs11190607 chr10:102303614 C/T cg16342193 chr10:102329863 NA -0.4 -4.89 -0.4 3.08e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg04546413 chr19:29218101 NA 0.83 6.68 0.51 7.35e-10 Methadone dose in opioid dependence; TGCT cis rs950169 0.922 rs62028133 chr15:84919375 A/C cg17173187 chr15:85201210 NMB 0.54 5.55 0.45 1.67e-7 Schizophrenia; TGCT cis rs10901296 0.588 rs12003046 chr9:133741626 T/C cg03924115 chr9:133768966 QRFP 0.27 4.57 0.38 1.14e-5 Bilirubin levels; TGCT cis rs2228479 0.850 rs12599473 chr16:89827435 A/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7809950 0.817 rs2222845 chr7:107281829 C/T cg23024343 chr7:107201750 COG5 0.48 6.85 0.52 3.11e-10 Coronary artery disease; TGCT cis rs4808199 0.901 rs12973258 chr19:19488718 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.69 4.99 0.41 2.02e-6 Nonalcoholic fatty liver disease; TGCT cis rs6500602 1.000 rs12447826 chr16:4464617 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.1 0.42 1.24e-6 Schizophrenia; TGCT cis rs3780378 0.935 rs7875908 chr9:5081334 C/T cg03508284 chr9:4985524 JAK2 -0.47 -4.44 -0.37 1.97e-5 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs9393777 0.513 rs6936555 chr6:26640886 C/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.51 -4.68 -0.39 7.36e-6 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs17162190 0.590 rs3127010 chr1:26782700 A/G cg02450742 chr1:26856648 RPS6KA1 -0.55 -4.61 -0.38 9.69e-6 Mean corpuscular volume; TGCT cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg23205692 chr1:25664452 TMEM50A 0.47 4.95 0.41 2.32e-6 Plateletcrit;Mean corpuscular volume; TGCT cis rs7027203 0.964 rs7853688 chr9:96523254 C/A cg14396892 chr9:96623032 NA 0.23 4.6 0.38 1.03e-5 DNA methylation (variation); TGCT cis rs2013441 1.000 rs9897328 chr17:20174852 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs921968 0.541 rs7603816 chr2:219396255 C/T cg02176678 chr2:219576539 TTLL4 -0.49 -6.94 -0.53 1.95e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2013441 1.000 rs9896709 chr17:20180550 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs6840360 0.573 rs11099806 chr4:152269116 G/T cg17479576 chr4:152424074 FAM160A1 -0.45 -4.77 -0.39 5.1e-6 Intelligence (multi-trait analysis); TGCT cis rs3008870 1.000 rs3008870 chr1:67418027 C/T cg03991309 chr1:68237761 GNG12 0.27 4.57 0.38 1.18e-5 Lymphocyte percentage of white cells; TGCT cis rs2370759 1.000 rs79806114 chr10:32618022 T/C cg01819863 chr10:32635814 EPC1 1.03 10.0 0.67 1.27e-17 Sexual dysfunction (female); TGCT cis rs7267979 1.000 rs11087520 chr20:25436827 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11190604 0.767 rs7085426 chr10:102163640 T/C cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12142240 0.698 rs6695043 chr1:46844530 A/G cg00530320 chr1:46809349 NSUN4 -0.29 -5.73 -0.46 7.12e-8 Menopause (age at onset); TGCT cis rs11190604 1.000 rs11190601 chr10:102296730 A/G cg16342193 chr10:102329863 NA -0.41 -5.37 -0.43 3.78e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7937682 1.000 rs9734135 chr11:111536190 G/A cg09085632 chr11:111637200 PPP2R1B -1.05 -10.05 -0.67 9.54e-18 Primary sclerosing cholangitis; TGCT cis rs4332037 0.539 rs4719416 chr7:2106608 G/A cg24505167 chr7:1915268 MAD1L1 -0.28 -4.69 -0.39 7.11e-6 Bipolar disorder; TGCT cis rs734999 0.545 rs4474198 chr1:2553758 C/T cg18854424 chr1:2615690 NA 0.5 5.95 0.47 2.54e-8 Ulcerative colitis; TGCT cis rs9303542 0.625 rs9904760 chr17:46575031 C/T cg25032089 chr17:46643351 HOXB3 0.49 5.36 0.43 3.93e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs57221529 0.713 rs12522724 chr5:590742 T/C cg09021430 chr5:549028 NA -0.38 -5.06 -0.41 1.45e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7267979 0.706 rs6037069 chr20:25234166 C/T cg14121845 chr20:25566513 NINL 0.48 5.22 0.42 7.27e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg17554472 chr22:41940697 POLR3H -0.5 -5.2 -0.42 8.14e-7 Vitiligo; TGCT cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs6121246 0.529 rs6060118 chr20:30171209 T/C cg18721089 chr20:30220636 NA -0.58 -6.34 -0.5 3.81e-9 Mean corpuscular hemoglobin; TGCT cis rs1215050 0.791 rs1648546 chr4:98899294 T/C cg17366294 chr4:99064904 C4orf37 -0.53 -5.69 -0.45 8.67e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg16414030 chr3:133502952 NA -0.67 -11.16 -0.71 1.94e-20 Iron status biomarkers; TGCT cis rs6835174 0.730 rs74217404 chr4:5987735 C/T cg13644262 chr4:6449564 PPP2R2C -0.34 -4.74 -0.39 5.88e-6 Cannabis use (initiation); TGCT cis rs12682352 0.602 rs4841044 chr8:8664940 A/G cg15556689 chr8:8085844 FLJ10661 -0.62 -5.5 -0.44 2.1e-7 Neuroticism; TGCT cis rs3739821 0.793 rs7023663 chr9:130714930 T/C cg17308606 chr9:130706144 FAM102A 0.28 4.59 0.38 1.08e-5 Glaucoma (primary angle closure); TGCT cis rs6684514 1.000 rs12045339 chr1:156294211 C/T cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs78461346 0.610 rs117607873 chr17:80476066 G/A cg15014069 chr17:80540666 FOXK2 0.4 5.27 0.43 5.9e-7 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs10791097 0.667 rs4937584 chr11:130741761 A/G cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg12310025 chr6:25882481 NA -0.52 -5.28 -0.43 5.47e-7 Height; TGCT cis rs28785552 0.769 rs7253672 chr19:53243212 G/C cg22067481 chr19:53234126 ZNF611 -0.47 -6.81 -0.52 3.68e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs10927875 0.615 rs10927886 chr1:16339313 C/G cg21385522 chr1:16154831 NA -0.46 -4.86 -0.4 3.42e-6 Dilated cardiomyopathy; TGCT cis rs5769765 1.000 rs910800 chr22:50278642 C/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.07 -0.48 1.46e-8 Schizophrenia; TGCT cis rs698833 0.506 rs713448 chr2:44504877 T/C cg00619915 chr2:44497795 NA -0.22 -4.95 -0.41 2.38e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs7044106 0.791 rs4617229 chr9:123480696 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.78 0.39 4.8e-6 Hip circumference adjusted for BMI; TGCT cis rs10088262 0.629 rs1367829 chr8:124797135 A/G cg20713898 chr8:124780851 FAM91A1 -0.84 -7.19 -0.54 5.3e-11 Pancreatic cancer; TGCT cis rs59698941 0.527 rs1557852 chr5:132181800 G/A cg21474247 chr5:131268130 NA 0.31 4.97 0.41 2.16e-6 Apolipoprotein A-IV levels; TGCT cis rs1691799 0.899 rs1168329 chr12:66731864 C/A cg16791601 chr12:66731901 HELB -0.29 -6.38 -0.5 3.25e-9 White blood cell count (basophil); TGCT cis rs524281 0.814 rs10896098 chr11:65968416 G/A cg00563793 chr11:65837595 PACS1 0.53 4.67 0.39 7.6e-6 Electroencephalogram traits; TGCT cis rs4663866 0.901 rs35713061 chr2:239183774 C/T cg17283117 chr2:239148619 HES6 0.99 4.58 0.38 1.12e-5 Irritable bowel syndrome; TGCT cis rs7524258 0.903 rs763197 chr1:7289959 A/G cg04342483 chr1:7259290 CAMTA1 -0.31 -4.49 -0.37 1.6e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg02503808 chr4:7069936 GRPEL1 0.98 9.27 0.64 7.53e-16 Monocyte percentage of white cells; TGCT cis rs2242116 0.932 rs4683301 chr3:46931478 A/T cg16339096 chr3:46934204 PTH1R -0.41 -4.61 -0.38 9.67e-6 Birth weight; TGCT cis rs459571 0.959 rs2520100 chr9:136918137 A/T cg14405625 chr9:136855902 VAV2 -0.32 -4.72 -0.39 6.15e-6 Platelet distribution width; TGCT cis rs200810 0.664 rs35600586 chr6:98008034 G/A cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.64 -4.45 -0.37 1.91e-5 Body mass index; TGCT cis rs3008870 0.792 rs72673729 chr1:67441673 T/TG cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.89 -0.73 3.12e-22 Lymphocyte percentage of white cells; TGCT cis rs858239 0.539 rs10279194 chr7:23191083 T/C cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9383153 1.000 rs9370887 chr6:16329258 G/C cg14009473 chr6:15502099 JARID2 0.61 4.85 0.4 3.62e-6 Gambling; TGCT cis rs1475911 1.000 rs55645900 chr21:43515728 G/T cg14562523 chr21:43528734 C21orf128;UMODL1 -0.26 -5.07 -0.41 1.4e-6 IgG glycosylation; TGCT cis rs8072100 0.713 rs8074451 chr17:45477573 C/T cg08085267 chr17:45401833 C17orf57 -0.51 -5.57 -0.45 1.51e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs28595532 1.000 rs114778020 chr4:119662584 C/A cg21605333 chr4:119757512 SEC24D 1.4 7.94 0.58 1.04e-12 Cannabis dependence symptom count; TGCT cis rs1215050 0.567 rs1567288 chr4:98582985 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.8 -0.4 4.45e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg03517284 chr6:25882590 NA -0.52 -4.66 -0.39 7.92e-6 Intelligence (multi-trait analysis); TGCT cis rs2795502 0.873 rs3121282 chr10:43423626 T/A cg20628663 chr10:43360327 NA 0.35 5.21 0.42 7.79e-7 Blood protein levels; TGCT cis rs12142240 0.698 rs10158572 chr1:46822440 G/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs11992186 0.505 rs7845203 chr8:8145440 A/G cg06636001 chr8:8085503 FLJ10661 0.58 4.89 0.4 3.05e-6 Neuroticism; TGCT cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4819052 0.851 rs8133045 chr21:46658137 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12210905 1.000 rs72843619 chr6:27154830 A/G cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs7659604 0.539 rs56159666 chr4:122782879 G/A cg20573242 chr4:122745356 CCNA2 0.63 5.54 0.45 1.72e-7 Type 2 diabetes; TGCT cis rs319204 1.000 rs319233 chr5:146241258 C/T cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.05 0.41 1.51e-6 Menopause (age at onset); TGCT cis rs6500602 0.727 rs12443748 chr16:4541831 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.52 0.44 1.86e-7 Schizophrenia; TGCT cis rs295140 0.743 rs952530 chr2:201081745 A/G cg04283868 chr2:201171347 SPATS2L 0.53 5.25 0.43 6.53e-7 QT interval; TGCT cis rs55962025 0.883 rs3121419 chr4:3232257 C/T cg06533319 chr4:3265114 C4orf44 0.24 4.72 0.39 6.35e-6 Parental longevity (mother's age at death); TGCT cis rs6490294 0.904 rs2339908 chr12:112418496 G/A cg10833066 chr12:111807467 FAM109A 0.35 5.13 0.42 1.09e-6 Mean platelet volume; TGCT cis rs1568889 0.730 rs6484350 chr11:28113658 G/A cg06544937 chr11:28130018 METT5D1;KIF18A -0.92 -11.35 -0.71 6.62e-21 Bipolar disorder; TGCT cis rs807669 0.903 rs1018764 chr22:19172006 T/C cg02655711 chr22:19163373 SLC25A1 0.42 10.01 0.67 1.23e-17 Metabolite levels; TGCT cis rs1215050 0.765 rs181521 chr4:98745728 A/C cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1552244 0.882 rs13100734 chr3:10022878 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.16e-10 Alzheimer's disease; TGCT cis rs12541335 0.639 rs3923439 chr8:22170079 G/A cg18135555 chr8:22132992 PIWIL2 0.29 5.98 0.47 2.23e-8 Hypertriglyceridemia; TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs12142240 0.698 rs67941619 chr1:46838219 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs9467773 1.000 rs1321480 chr6:26532742 A/G cg05738196 chr6:26577821 NA 0.88 12.46 0.75 1.33e-23 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9549367 0.789 rs2316442 chr13:113877487 C/T cg00898013 chr13:113819073 PROZ -0.39 -4.76 -0.39 5.36e-6 Platelet distribution width; TGCT cis rs9430161 0.579 rs9659356 chr1:11034817 A/G cg02454025 chr1:11042201 C1orf127 0.95 12.18 0.74 6.17e-23 Ewing sarcoma; TGCT cis rs7246657 0.678 rs2927740 chr19:38140966 A/G cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT cis rs6582630 0.555 rs10880613 chr12:38509553 C/T cg26384229 chr12:38710491 ALG10B 0.89 8.14 0.59 3.55e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs71636778 0.509 rs6656815 chr1:27292462 G/A cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs7267979 0.586 rs6050439 chr20:25192331 T/C cg03522245 chr20:25566470 NINL 0.5 5.24 0.43 6.66e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11874712 1.000 rs9945606 chr18:43673325 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs4478858 0.735 rs6685728 chr1:31802550 T/C cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs3806843 0.676 rs2569159 chr5:140030710 C/T cg19875535 chr5:140030758 IK -0.36 -6.26 -0.49 5.68e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs17433780 0.928 rs12127787 chr1:89458761 T/C cg09516651 chr1:89888402 LOC400759 0.32 5.89 0.47 3.35e-8 Carotid intima media thickness; TGCT cis rs2197308 0.740 rs11182967 chr12:37935140 A/C cg26384229 chr12:38710491 ALG10B 0.87 7.83 0.58 1.85e-12 Morning vs. evening chronotype; TGCT cis rs2880765 0.835 rs4843063 chr15:86048748 G/T cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs8051431 0.504 rs2335711 chr16:71907559 T/A cg06353428 chr16:71660113 MARVELD3 0.83 6.97 0.53 1.65e-10 LDL cholesterol levels; TGCT cis rs17826219 0.706 rs55764512 chr17:29085758 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg10819733 chr22:24237672 NA 0.28 4.59 0.38 1.09e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs783396 0.818 rs2353043 chr6:107000383 C/T cg27564810 chr2:201635376 AOX2P -0.43 -6.75 -0.52 5.02e-10 Stroke; TGCT cis rs916888 0.821 rs415430 chr17:44859144 C/T cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs644799 0.710 rs1852535 chr11:95501241 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.8 8.99 0.63 3.39e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs610932 0.517 rs1530915 chr11:60028917 A/G cg18570331 chr11:60101691 MS4A6E 0.5 4.44 0.37 1.93e-5 Alzheimer's disease; TGCT cis rs797680 0.856 rs6688230 chr1:93641124 C/T cg17826107 chr1:92977322 EVI5 -0.24 -5.27 -0.43 5.93e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg01448562 chr3:133502909 NA -0.26 -4.94 -0.41 2.46e-6 Iron status biomarkers; TGCT cis rs801193 0.569 rs7782587 chr7:66166472 C/T cg11764359 chr7:65958608 NA 0.54 4.85 0.4 3.67e-6 Aortic root size; TGCT cis rs12142240 0.698 rs66911505 chr1:46823298 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs62283056 0.512 rs4568307 chr4:6284965 A/G cg25554036 chr4:6271136 WFS1 0.56 7.26 0.55 3.68e-11 Cisplatin-induced ototoxicity; TGCT cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg13395646 chr4:1353034 KIAA1530 -0.36 -4.47 -0.37 1.72e-5 Obesity-related traits; TGCT cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs7777754 0.512 rs3757472 chr7:50537983 A/C cg18232548 chr7:50535776 DDC -0.39 -6.03 -0.48 1.72e-8 Response to zileuton treatment in asthma (FEV1 change interaction); TGCT cis rs28595532 1.000 rs28595532 chr4:119716950 A/C cg21605333 chr4:119757512 SEC24D 1.22 7.4 0.55 1.83e-11 Cannabis dependence symptom count; TGCT cis rs4665809 1.000 rs2384322 chr2:26291146 C/G cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs428668 0.523 rs6898671 chr5:150677643 A/T cg11125805 chr5:150678162 SLC36A3 0.32 8.06 0.59 5.36e-13 Skin aging (microtopography measurement); TGCT cis rs4919044 0.641 rs11187231 chr10:94736462 T/A cg05127821 chr10:94822908 CYP26C1 -0.73 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs4812048 1.000 rs6070692 chr20:57586374 A/G cg24457521 chr20:57607420 ATP5E -0.7 -4.58 -0.38 1.13e-5 Mean platelet volume; TGCT cis rs1008375 1.000 rs2315556 chr4:17670861 T/C cg16339924 chr4:17578868 LAP3 0.55 4.76 0.39 5.3e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17826219 0.500 rs57005940 chr17:29066329 C/G cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Body mass index; TGCT cis rs7513165 0.932 rs12040580 chr1:204148168 T/C cg04791601 chr1:204159016 NA 0.25 5.09 0.42 1.32e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs877282 0.898 rs36064821 chr10:760952 C/T cg17470449 chr10:769945 NA 0.36 5.35 0.43 4.04e-7 Uric acid levels; TGCT cis rs589448 0.967 rs2617835 chr12:69753420 C/A cg20891283 chr12:69753455 YEATS4 0.91 10.33 0.68 1.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6988636 1.000 rs61422480 chr8:124188940 C/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg17747265 chr1:1875780 NA -0.42 -8.11 -0.59 4.23e-13 Body mass index; TGCT cis rs7917772 0.503 rs56397707 chr10:104302693 T/C cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17401966 0.838 rs12125535 chr1:10350849 T/A cg19773385 chr1:10388646 KIF1B -0.21 -4.57 -0.38 1.17e-5 Hepatocellular carcinoma; TGCT cis rs7412746 0.611 rs10888395 chr1:150762171 C/T cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs4325129 0.954 rs12118188 chr1:159492663 T/A cg07417683 chr1:159440267 NA -0.45 -4.59 -0.38 1.07e-5 Obesity-related traits; TGCT cis rs4788570 0.578 rs8062188 chr16:71729825 T/C cg06353428 chr16:71660113 MARVELD3 1.57 13.04 0.76 5.38e-25 Intelligence (multi-trait analysis); TGCT cis rs7439150 1.000 rs4333166 chr4:155481511 A/G cg22130008 chr4:155548532 NA 0.4 4.86 0.4 3.46e-6 Fibrinogen levels; TGCT cis rs13108904 0.846 rs4974574 chr4:1224811 A/G cg03303774 chr4:1407052 NA 0.27 4.48 0.37 1.7e-5 Obesity-related traits; TGCT cis rs7258465 0.931 rs875396 chr19:18611147 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs556990 0.574 rs473598 chr13:113801189 C/T cg18105134 chr13:113819100 PROZ -0.44 -7.46 -0.56 1.34e-11 Blood protein levels; TGCT cis rs4595586 0.545 rs4768505 chr12:39380338 C/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7216064 1.000 rs58122682 chr17:65876915 T/C cg12091567 chr17:66097778 LOC651250 -0.82 -6.37 -0.5 3.32e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs12477438 0.798 rs13409996 chr2:99575497 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs35306767 0.715 rs17221456 chr10:1037234 T/C cg20503657 chr10:835505 NA 0.63 6.97 0.53 1.64e-10 Eosinophil percentage of granulocytes; TGCT cis rs12908161 1.000 rs12908161 chr15:85207825 A/G cg12863693 chr15:85201151 NMB 0.46 5.53 0.44 1.79e-7 Schizophrenia; TGCT cis rs7258465 0.965 rs7253990 chr19:18604085 C/G cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs10493773 0.609 rs3753789 chr1:86174814 T/C cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs832540 0.552 rs702681 chr5:56218029 C/T cg12311346 chr5:56204834 C5orf35 -0.55 -5.48 -0.44 2.23e-7 Coronary artery disease; TGCT cis rs9914988 0.943 rs67327562 chr17:27108828 G/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs6570726 0.791 rs418701 chr6:145889992 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2334880 0.678 rs6499520 chr16:71458100 C/T cg06353428 chr16:71660113 MARVELD3 -1.26 -8.32 -0.6 1.34e-13 Malaria; TGCT cis rs9303401 0.659 rs66514313 chr17:56714057 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg26119090 chr2:26468346 HADHA;HADHB -0.85 -6.05 -0.48 1.57e-8 Gut microbiome composition (summer); TGCT cis rs7582180 0.629 rs13004216 chr2:100945402 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs7192750 0.586 rs6499552 chr16:71943169 G/C cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9814567 0.858 rs4955548 chr3:134341060 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -8.62 -0.61 2.62e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9611565 0.649 rs139553 chr22:42187199 A/G cg03806693 chr22:41940476 POLR3H 0.95 9.29 0.64 6.6e-16 Vitiligo; TGCT cis rs6951245 0.786 rs77943789 chr7:1140158 C/T cg03188948 chr7:1209495 NA 0.64 5.77 0.46 6.01e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.962 rs11932892 chr4:99072967 C/T cg18180107 chr4:99064573 C4orf37 0.61 4.63 0.38 8.94e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.882 rs61429272 chr3:10037320 G/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs8141529 0.764 rs5752812 chr22:29225603 T/A cg02153584 chr22:29168773 CCDC117 0.67 5.69 0.45 8.82e-8 Lymphocyte counts; TGCT cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs9911578 1.000 rs2567911 chr17:56734977 A/G cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs12762955 0.561 rs6560863 chr10:1013535 C/A cg18964960 chr10:1102726 WDR37 -0.65 -5.81 -0.46 4.9e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs8031584 0.652 rs2691683 chr15:31135060 A/G cg14829155 chr15:31115871 NA 0.36 4.72 0.39 6.14e-6 Huntington's disease progression; TGCT cis rs10744422 0.748 rs2292138 chr12:123339712 A/G cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs7582180 0.764 rs10180423 chr2:100919012 C/G cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.45e-6 Intelligence (multi-trait analysis); TGCT cis rs12541335 0.639 rs7003478 chr8:22201123 A/G cg09517075 chr8:22133004 PIWIL2 0.25 4.97 0.41 2.21e-6 Hypertriglyceridemia; TGCT cis rs4460629 0.742 rs4625273 chr1:155076043 C/T cg23973274 chr1:155060172 NA -0.26 -4.66 -0.39 8.1e-6 Serum magnesium levels; TGCT cis rs7772486 0.875 rs7766595 chr6:146364507 A/T cg23711669 chr6:146136114 FBXO30 0.87 9.53 0.65 1.75e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg13695892 chr22:41940480 POLR3H 0.88 8.64 0.61 2.39e-14 Vitiligo; TGCT cis rs7666738 0.753 rs2865957 chr4:99040725 G/A cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs453301 0.719 rs34004903 chr8:8892604 C/T cg00184457 chr8:8946301 NA -0.26 -4.94 -0.41 2.45e-6 Joint mobility (Beighton score); TGCT cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2721195 0.816 rs4925826 chr8:145706276 G/A cg17328964 chr8:145687451 CYHR1 -0.45 -6.35 -0.5 3.64e-9 Age at first birth; TGCT cis rs66573146 1.000 rs6812771 chr4:6964048 G/A cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs13256369 1.000 rs10095733 chr8:8574646 A/G cg06671706 chr8:8559999 CLDN23 0.35 4.62 0.38 9.35e-6 Obesity-related traits; TGCT cis rs36051895 0.664 rs10815157 chr9:5108771 C/G cg02405213 chr9:5042618 JAK2 -0.74 -9.85 -0.66 2.99e-17 Pediatric autoimmune diseases; TGCT cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs10949834 0.618 rs810551 chr7:73492093 C/G cg07137043 chr7:73588983 EIF4H -0.59 -4.73 -0.39 5.96e-6 Verbal memory performance (residualized delayed recall change); TGCT cis rs11644362 0.932 rs3848239 chr16:12996642 A/G cg06890432 chr16:12997467 SHISA9 -0.6 -6.59 -0.51 1.11e-9 Positive affect;Subjective well-being; TGCT cis rs6429082 0.715 rs2172718 chr1:235580727 A/G cg26050004 chr1:235667680 B3GALNT2 -0.57 -5.03 -0.41 1.7e-6 Adiposity; TGCT cis rs9322193 0.923 rs9800580 chr6:149953981 C/T cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg17264618 chr3:40429014 ENTPD3 0.32 4.69 0.39 7e-6 Renal cell carcinoma; TGCT cis rs9611565 0.879 rs5758307 chr22:41750219 A/G cg17554472 chr22:41940697 POLR3H -0.45 -4.77 -0.39 5.1e-6 Vitiligo; TGCT cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7226408 0.749 rs17567737 chr18:34499369 A/T cg06757138 chr18:34340585 FHOD3 0.24 4.59 0.38 1.06e-5 Obesity-related traits; TGCT cis rs9911578 1.000 rs304292 chr17:56824123 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs801193 0.569 rs7800620 chr7:66223688 T/C cg11764359 chr7:65958608 NA 0.52 4.6 0.38 1.04e-5 Aortic root size; TGCT cis rs11030122 0.673 rs10835596 chr11:4099666 C/T cg18678763 chr11:4115507 RRM1 -0.46 -5.59 -0.45 1.38e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs4499344 0.556 rs259227 chr19:33134791 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.26 0.6 1.84e-13 Mean platelet volume; TGCT cis rs1401999 1.000 rs6805913 chr3:183662924 T/G cg01324343 chr3:183735012 ABCC5 0.82 10.93 0.7 6.83e-20 Anterior chamber depth; TGCT cis rs6490294 0.649 rs7306804 chr12:112441089 A/G cg10833066 chr12:111807467 FAM109A 0.37 5.78 0.46 5.71e-8 Mean platelet volume; TGCT cis rs950169 0.580 rs11634322 chr15:85172209 C/T cg17173187 chr15:85201210 NMB 0.62 7.09 0.54 8.99e-11 Schizophrenia; TGCT cis rs7772486 0.521 rs9485017 chr6:146023326 C/T cg13319975 chr6:146136371 FBXO30 -0.63 -5.77 -0.46 6.08e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs727563 0.635 rs5751141 chr22:42107745 A/G cg06481639 chr22:41940642 POLR3H 0.74 6.64 0.51 8.66e-10 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4595586 0.525 rs7968458 chr12:39377139 C/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs12935418 0.583 rs12446698 chr16:80964421 G/A cg07676361 chr16:80966860 NA -0.35 -4.66 -0.39 8.02e-6 Mean corpuscular volume; TGCT cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg13393036 chr8:95962371 TP53INP1 -0.59 -8.08 -0.59 4.92e-13 Type 2 diabetes; TGCT cis rs6088580 0.608 rs2105109 chr20:32971932 A/G cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs62318470 chr4:98925846 A/C cg17366294 chr4:99064904 C4orf37 0.72 7.19 0.54 5.3e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg20637647 chr7:64974828 NA 0.88 5.34 0.43 4.19e-7 Diabetic kidney disease; TGCT cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg10117171 chr1:25599238 RHD -0.32 -5.31 -0.43 4.85e-7 Erythrocyte sedimentation rate; TGCT cis rs1577917 0.771 rs2842608 chr6:86295858 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.57 -0.45 1.5e-7 Response to antipsychotic treatment; TGCT cis rs10992471 0.603 rs10114932 chr9:95307901 C/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.68 -0.45 9.01e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9682041 0.696 rs11927807 chr3:170096623 A/G cg11886554 chr3:170076028 SKIL 0.61 4.78 0.39 4.77e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7611238 0.560 rs12054139 chr3:195098427 T/C cg27323046 chr3:195102265 ACAP2 0.37 4.93 0.4 2.56e-6 Body mass index; TGCT cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.587 rs4077828 chr17:17833644 A/T cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs7582180 0.764 rs10460478 chr2:100919735 G/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.89e-7 Intelligence (multi-trait analysis); TGCT cis rs1348850 0.602 rs1453373 chr2:178221668 G/A cg22681709 chr2:178499509 PDE11A -0.34 -4.48 -0.37 1.65e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs35374984 1.000 rs35374984 chr10:30234190 C/A cg22629853 chr10:30638455 MTPAP -0.57 -5.51 -0.44 1.94e-7 Emphysema distribution in smoking; TGCT cis rs7017914 0.934 rs62508771 chr8:71692688 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs34783982 0.529 rs8039998 chr15:89474659 C/T cg26213453 chr15:89455860 MFGE8 0.33 4.86 0.4 3.5e-6 Squamous cell lung carcinoma; TGCT cis rs7267979 1.000 rs4815421 chr20:25386509 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs877282 0.898 rs11253352 chr10:766598 C/A cg22713356 chr15:30763199 NA 1.15 9.41 0.65 3.45e-16 Uric acid levels; TGCT cis rs7474896 0.507 rs2474555 chr10:38465220 G/C cg25427524 chr10:38739819 LOC399744 -0.35 -4.55 -0.38 1.24e-5 Obesity (extreme); TGCT cis rs5771225 0.563 rs6010220 chr22:50693554 A/G cg16473166 chr22:50639996 SELO 0.69 5.69 0.45 8.74e-8 Late-onset Alzheimer's disease; TGCT cis rs6964587 0.843 rs56075286 chr7:91731518 G/A cg22709100 chr7:91322751 NA 0.28 4.58 0.38 1.12e-5 Breast cancer; TGCT cis rs12579753 0.879 rs7958566 chr12:82131478 A/T cg07988820 chr12:82153109 PPFIA2 -0.68 -7.32 -0.55 2.7e-11 Resting heart rate; TGCT cis rs41271473 0.500 rs4606285 chr1:228887544 G/T cg10167378 chr1:228756711 NA 0.5 4.56 0.38 1.19e-5 Chronic lymphocytic leukemia; TGCT cis rs10771431 0.967 rs7137443 chr12:9372029 C/T cg13987825 chr12:9392948 NA -0.27 -4.49 -0.37 1.63e-5 Breast size; TGCT cis rs7635838 0.892 rs9310384 chr3:11491980 A/G cg00170343 chr3:11313890 ATG7 0.64 5.94 0.47 2.69e-8 HDL cholesterol; TGCT cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg13395646 chr4:1353034 KIAA1530 -0.36 -4.62 -0.38 9.52e-6 Obesity-related traits; TGCT cis rs11098499 0.863 rs9884402 chr4:120489982 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs7017914 0.934 rs2732092 chr8:71918599 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.31 -0.43 4.8e-7 Bone mineral density; TGCT cis rs6964587 1.000 rs55745934 chr7:91670998 T/C cg17063962 chr7:91808500 NA 0.88 9.54 0.65 1.69e-16 Breast cancer; TGCT cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs950776 0.612 rs8038920 chr15:78974545 A/G cg03762349 chr15:79060523 ADAMTS7 -0.25 -5.33 -0.43 4.45e-7 Sudden cardiac arrest; TGCT cis rs2456568 0.805 rs55784864 chr11:93682887 G/A cg14065697 chr11:93583672 C11orf90 -0.38 -4.58 -0.38 1.13e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7267979 0.966 rs2151144 chr20:25414924 G/C cg14121845 chr20:25566513 NINL -0.5 -5.32 -0.43 4.73e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.8e-6 Obesity-related traits; TGCT cis rs9611565 0.625 rs12483991 chr22:41935285 A/G cg13695892 chr22:41940480 POLR3H -0.86 -8.85 -0.62 7.6e-15 Vitiligo; TGCT cis rs9611565 0.503 rs5751156 chr22:42170025 A/G cg13695892 chr22:41940480 POLR3H 0.84 7.89 0.58 1.34e-12 Vitiligo; TGCT cis rs17152411 0.895 rs61872118 chr10:126583450 C/T cg07906193 chr10:126599966 NA 0.43 5.25 0.43 6.46e-7 Height; TGCT cis rs875971 0.862 rs6952182 chr7:65683317 T/G cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.94e-6 Aortic root size; TGCT cis rs7552404 1.000 rs4646961 chr1:76217169 G/A cg10523679 chr1:76189770 ACADM 0.89 9.53 0.65 1.72e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6582630 0.555 rs34884627 chr12:38443831 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg21951975 chr1:209979733 IRF6 -0.66 -5.75 -0.46 6.51e-8 Cleft lip with or without cleft palate; TGCT cis rs2439831 0.681 rs7175434 chr15:43628542 A/C cg02155558 chr15:43621948 ADAL;LCMT2 1.04 8.86 0.62 7.03e-15 Lung cancer in ever smokers; TGCT cis rs713587 0.935 rs4430895 chr2:25161386 C/T cg15423357 chr2:25149977 NA 0.58 5.85 0.47 4.03e-8 Body mass index in non-asthmatics; TGCT cis rs9906944 0.545 rs11079850 chr17:47092252 G/T cg20966754 chr17:47091339 IGF2BP1 -0.41 -4.48 -0.37 1.65e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs10782582 0.593 rs11578480 chr1:76208989 T/G cg10523679 chr1:76189770 ACADM -0.67 -6.71 -0.52 6.18e-10 Daytime sleep phenotypes; TGCT cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg26531700 chr6:26746687 NA 0.61 5.84 0.46 4.23e-8 Intelligence (multi-trait analysis); TGCT cis rs11935103 0.569 rs7656944 chr4:187294897 C/G cg16785698 chr4:186456103 PDLIM3 0.45 4.57 0.38 1.18e-5 Response to citalopram treatment; TGCT cis rs2932538 0.961 rs3013441 chr1:113192605 C/T cg22162597 chr1:113214053 CAPZA1 -0.31 -6.31 -0.49 4.42e-9 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1371867 0.846 rs1788203 chr8:101303721 T/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs1372520 0.873 rs2736989 chr4:90776257 T/C cg01966878 chr4:90757139 SNCA -0.3 -4.71 -0.39 6.55e-6 Neuroticism; TGCT cis rs12477438 0.765 rs2309521 chr2:99592069 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs11098499 0.644 rs28787668 chr4:120554687 G/A cg09307838 chr4:120376055 NA 0.62 5.87 0.47 3.71e-8 Corneal astigmatism; TGCT cis rs4906332 1.000 rs7155822 chr14:103922390 A/G cg26031613 chr14:104095156 KLC1 -0.52 -4.65 -0.39 8.5e-6 Coronary artery disease; TGCT cis rs1401999 1.000 rs6802849 chr3:183698943 A/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs5769707 0.967 rs8141807 chr22:50043738 C/G cg10356904 chr22:49881777 NA -0.22 -4.52 -0.38 1.4e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6831352 0.918 rs13140423 chr4:100050400 T/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs9611565 0.580 rs5758449 chr22:42140160 C/T cg17554472 chr22:41940697 POLR3H 0.43 4.54 0.38 1.31e-5 Vitiligo; TGCT cis rs6754311 0.593 rs1446584 chr2:136419961 C/T cg07169764 chr2:136633963 MCM6 -0.68 -6.14 -0.48 1.03e-8 Mosquito bite size; TGCT cis rs17826219 0.500 rs2874724 chr17:29072433 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs7666738 0.830 rs10470951 chr4:99037051 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.877 rs28575883 chr5:93346035 T/C cg09848695 chr5:92956644 FAM172A;MIR2277 0.62 4.44 0.37 1.98e-5 Diabetic retinopathy; TGCT cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg11502198 chr6:26597334 ABT1 0.53 4.93 0.41 2.53e-6 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.720 rs6590516 chr11:130733393 G/T cg12179176 chr11:130786555 SNX19 0.83 10.09 0.67 7.59e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9443645 0.901 rs55755815 chr6:79607121 G/T cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs12682352 0.602 rs11783966 chr8:8665147 A/G cg08975724 chr8:8085496 FLJ10661 -0.53 -4.66 -0.39 8.09e-6 Neuroticism; TGCT cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs6545883 0.929 rs1186700 chr2:61663372 A/C cg15711740 chr2:61764176 XPO1 -0.52 -4.67 -0.39 7.58e-6 Tuberculosis; TGCT cis rs7666738 0.830 rs36028444 chr4:98968635 G/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs6671200 1.000 rs12749053 chr1:95660556 A/G cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs854765 0.547 rs4925135 chr17:17952868 T/C cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs4891159 0.527 rs690593 chr18:74160408 C/G cg24786174 chr18:74118243 ZNF516 0.63 10.66 0.69 3.07e-19 Longevity; TGCT cis rs9914544 1.000 rs28436199 chr17:18751730 C/T cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.42 1.33e-6 Educational attainment (years of education); TGCT cis rs6540559 0.673 rs17015218 chr1:209967915 A/G cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs10946940 0.965 rs6921256 chr6:27587518 C/T cg10876282 chr6:28092338 ZSCAN16 0.48 4.83 0.4 4e-6 Systemic lupus erythematosus; TGCT cis rs72781680 1.000 rs7581107 chr2:24173565 C/T cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs10114408 0.959 rs10739964 chr9:96651432 T/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.13 -0.54 7.37e-11 Colorectal cancer; TGCT cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg08645402 chr16:4508243 NA 0.21 5.09 0.42 1.27e-6 Schizophrenia; TGCT cis rs950776 0.642 rs58946838 chr15:78961449 A/C cg21242079 chr15:79101063 ADAMTS7 -0.3 -4.58 -0.38 1.13e-5 Sudden cardiac arrest; TGCT cis rs826838 0.935 rs10875816 chr12:38955014 C/A cg13010199 chr12:38710504 ALG10B 0.8 6.77 0.52 4.58e-10 Heart rate; TGCT cis rs709400 0.628 rs1989565 chr14:103862193 G/A cg26031613 chr14:104095156 KLC1 -0.83 -9.22 -0.64 9.94e-16 Body mass index; TGCT cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg05896524 chr21:47604654 C21orf56 0.44 4.55 0.38 1.24e-5 Testicular germ cell tumor; TGCT cis rs7020830 0.931 rs6476613 chr9:37084340 A/G cg14294708 chr9:37120828 ZCCHC7 1.2 18.29 0.85 5.19e-37 Schizophrenia; TGCT cis rs7044106 0.791 rs10985008 chr9:123492960 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 7.83 0.58 1.82e-12 Hip circumference adjusted for BMI; TGCT cis rs10080237 0.564 rs2490230 chr6:80812464 G/A cg08355045 chr6:80787529 NA 0.33 5.69 0.45 8.76e-8 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals; TGCT cis rs644799 0.965 rs11021317 chr11:95517576 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.53 0.61 4.41e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9309473 0.632 rs7599076 chr2:73585519 G/T cg20560298 chr2:73613845 ALMS1 -0.41 -4.54 -0.38 1.31e-5 Metabolite levels; TGCT cis rs3845702 0.736 rs6433816 chr2:180809317 G/C cg01881094 chr2:180872142 CWC22 -1.03 -6.51 -0.5 1.72e-9 Schizophrenia; TGCT cis rs910316 1.000 rs10142865 chr14:75555624 G/A cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs986417 0.818 rs2882601 chr14:61096879 A/T cg27398547 chr14:60952738 C14orf39 1.44 10.1 0.67 7.17e-18 Gut microbiota (bacterial taxa); TGCT cis rs9611565 0.592 rs5751101 chr22:41828111 C/T cg13695892 chr22:41940480 POLR3H 0.9 9.06 0.63 2.38e-15 Vitiligo; TGCT cis rs2692947 0.673 rs584811 chr2:97069879 A/G cg22654517 chr2:96458247 NA -0.2 -4.6 -0.38 1.05e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4555082 0.834 rs2735822 chr14:105712734 C/T cg01266790 chr14:105781312 PACS2 0.55 4.49 0.37 1.58e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs7660520 0.524 rs4862101 chr4:183733177 T/C cg04181038 chr4:183730758 NA 0.65 6.11 0.48 1.2e-8 Pediatric autoimmune diseases; TGCT cis rs7614311 0.681 rs57766205 chr3:63895303 G/C cg22134162 chr3:63841271 THOC7 -0.35 -4.72 -0.39 6.29e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs459571 0.959 rs408307 chr9:136892523 A/G cg13789015 chr9:136890014 NCRNA00094 -0.42 -7.87 -0.58 1.51e-12 Platelet distribution width; TGCT cis rs4808199 0.894 rs9304960 chr19:19465529 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.33 0.43 4.49e-7 Nonalcoholic fatty liver disease; TGCT cis rs4727027 0.754 rs917124 chr7:148851213 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.57 5.0 0.41 1.91e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1218582 0.772 rs4845689 chr1:154885524 A/G cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT trans rs4332037 0.624 rs11764124 chr7:1891723 C/G cg25206134 chr2:45395956 NA 0.95 7.99 0.58 8.14e-13 Bipolar disorder; TGCT cis rs4808199 0.895 rs2163805 chr19:19575945 G/A cg03709012 chr19:19516395 GATAD2A 1.02 7.83 0.58 1.82e-12 Nonalcoholic fatty liver disease; TGCT cis rs2229238 0.911 rs7556449 chr1:154505886 C/T cg13067139 chr1:155221277 FAM189B -0.2 -4.51 -0.38 1.47e-5 Coronary heart disease; TGCT cis rs1541995 1.000 rs1541995 chr15:96316457 C/A cg00882281 chr15:96346592 NA 0.29 4.68 0.39 7.26e-6 Photic sneeze reflex; TGCT cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg04546413 chr19:29218101 NA 0.84 6.76 0.52 4.71e-10 Methadone dose in opioid dependence; TGCT cis rs9796 0.558 rs7166905 chr15:41514876 G/C cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.18 -0.54 5.56e-11 Menopause (age at onset); TGCT cis rs4924935 0.770 rs4924946 chr17:18846525 A/T cg26306683 chr17:18585705 ZNF286B -0.48 -4.46 -0.37 1.81e-5 Pancreatic cancer; TGCT cis rs1215050 0.791 rs165247 chr4:98692399 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9926296 0.744 rs154656 chr16:89708003 T/A cg04287289 chr16:89883240 FANCA -0.5 -4.76 -0.39 5.35e-6 Vitiligo; TGCT cis rs17122693 0.818 rs113230118 chr14:51160977 G/A cg04730355 chr14:51134070 SAV1 1.17 9.45 0.65 2.78e-16 Cognitive performance; TGCT cis rs9329289 0.632 rs2452187 chr10:2551147 C/G cg15501526 chr10:2543763 NA 0.43 4.73 0.39 6.13e-6 Age-related hearing impairment; TGCT cis rs9467711 0.606 rs9379897 chr6:26601526 T/C cg16898833 chr6:26189333 HIST1H4D 1.02 5.25 0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4664308 0.935 rs4637057 chr2:160950161 G/T cg03641300 chr2:160917029 PLA2R1 -0.28 -6.83 -0.52 3.44e-10 Idiopathic membranous nephropathy; TGCT cis rs7772486 0.654 rs6906402 chr6:146089307 C/G cg05347473 chr6:146136440 FBXO30 -0.53 -5.01 -0.41 1.84e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13008689 0.875 rs12616139 chr2:8522651 C/T cg21129864 chr2:9369739 ASAP2 0.18 4.47 0.37 1.73e-5 Longevity; TGCT cis rs1171582 0.584 rs10128501 chr10:61508784 A/G cg23572703 chr10:62241191 NA -0.27 -4.54 -0.38 1.31e-5 Alopecia areata; TGCT cis rs7659604 0.592 rs56077950 chr4:122721412 C/T cg06713675 chr4:122721982 EXOSC9 -0.69 -9.57 -0.65 1.4e-16 Type 2 diabetes; TGCT cis rs1865760 1.000 rs9393675 chr6:25930116 G/A cg16482183 chr6:26056742 HIST1H1C 0.51 4.57 0.38 1.17e-5 Height; TGCT cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2295359 0.892 rs56920441 chr1:67652012 A/G cg12940439 chr1:67600707 NA 0.59 6.16 0.48 9.32e-9 Psoriasis; TGCT cis rs1008375 0.966 rs12503517 chr4:17698725 G/A cg18681998 chr4:17616180 MED28 0.78 7.49 0.56 1.11e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2233152 0.611 rs28660501 chr19:41300277 G/T cg23743927 chr19:41304969 EGLN2 -0.69 -4.76 -0.39 5.4e-6 Kawasaki disease; TGCT cis rs8141529 0.748 rs5997412 chr22:29276747 G/A cg02153584 chr22:29168773 CCDC117 0.66 5.19 0.42 8.5e-7 Lymphocyte counts; TGCT cis rs9457247 0.935 rs2757046 chr6:167374353 C/T cg25258033 chr6:167368657 RNASET2 -0.18 -4.48 -0.37 1.65e-5 Crohn's disease; TGCT cis rs4595586 0.525 rs11613788 chr12:39390710 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs624899 1.000 rs624899 chr19:11612498 C/T cg14128973 chr19:11649462 CNN1 0.42 4.95 0.41 2.36e-6 Presence of antiphospholipid antibodies; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2777491 0.957 rs8026197 chr15:41711447 C/T cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.01 -0.7 4.47e-20 Ulcerative colitis; TGCT cis rs2580764 0.566 rs2968795 chr2:55287989 G/A cg09592903 chr2:55203963 RTN4 0.25 5.79 0.46 5.55e-8 Mean platelet volume; TGCT trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg22433210 chr17:43662623 NA 1.04 7.37 0.55 2.07e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg03517284 chr6:25882590 NA 0.89 9.16 0.64 1.32e-15 Blood metabolite levels; TGCT cis rs308403 0.509 rs309382 chr4:123669772 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.83 12.16 0.74 6.83e-23 Blood protein levels; TGCT cis rs1570884 0.556 rs2146146 chr13:50170368 C/T cg08779649 chr13:50194554 NA 0.37 5.82 0.46 4.74e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs4824093 0.541 rs8142132 chr22:50211294 C/T cg14114931 chr22:50943910 LMF2 0.45 5.29 0.43 5.39e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9303401 0.659 rs17822908 chr17:56801778 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs67311347 0.544 rs13097602 chr3:40339247 T/C cg13683864 chr3:40499215 RPL14 0.77 7.13 0.54 7.26e-11 Renal cell carcinoma; TGCT cis rs210152 0.541 rs35432298 chr6:33457013 T/A cg16739976 chr6:34101401 GRM4 0.57 4.72 0.39 6.15e-6 Schizophrenia; TGCT cis rs62103177 0.568 rs2365388 chr18:77973702 G/T cg07235805 chr18:78004237 PARD6G 0.52 4.97 0.41 2.18e-6 Opioid sensitivity; TGCT cis rs9807989 0.507 rs1420096 chr2:103010912 C/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs877282 1.000 rs11253367 chr10:773389 G/A cg17470449 chr10:769945 NA 0.31 4.88 0.4 3.2e-6 Uric acid levels; TGCT cis rs1008375 1.000 rs4698199 chr4:17656738 G/C cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg08280861 chr8:58055591 NA 0.52 5.78 0.46 5.78e-8 Developmental language disorder (linguistic errors); TGCT cis rs9733 0.526 rs11204696 chr1:150658721 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs55869953 chr4:119751893 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7829975 0.606 rs6422352 chr8:8794193 A/G cg15556689 chr8:8085844 FLJ10661 -0.7 -6.26 -0.49 5.66e-9 Mood instability; TGCT cis rs13108904 0.645 rs56115381 chr4:1324994 G/C cg03303774 chr4:1407052 NA 0.38 5.82 0.46 4.78e-8 Obesity-related traits; TGCT cis rs1865760 0.713 rs9461229 chr6:25992279 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 6.94 0.53 1.97e-10 Height; TGCT cis rs933688 1.000 rs6452953 chr5:90723034 T/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.49 0.69 8.29e-19 Smoking behavior; TGCT cis rs711830 1.000 rs711830 chr2:177037311 C/T cg13092806 chr2:177043255 NA -0.68 -5.65 -0.45 1.02e-7 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg17554472 chr22:41940697 POLR3H 0.5 5.16 0.42 9.35e-7 Vitiligo; TGCT trans rs7618501 0.699 rs2681781 chr3:49898273 A/G cg21659725 chr3:3221576 CRBN 0.77 8.99 0.63 3.47e-15 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs478647 chr11:68700424 C/T cg06028808 chr11:68637592 NA 0.53 6.86 0.52 2.89e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7552404 0.727 rs7547508 chr1:76327958 A/G cg10523679 chr1:76189770 ACADM -0.67 -6.27 -0.49 5.47e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12477438 0.520 rs11890338 chr2:99767868 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT trans rs57221529 0.713 rs12521091 chr5:590710 G/T cg25482853 chr8:67687455 SGK3 1.32 11.02 0.7 4.19e-20 Lung disease severity in cystic fibrosis; TGCT cis rs28595532 0.920 rs56117870 chr4:119766583 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs7044106 0.791 rs4617229 chr9:123480696 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 6.98 0.53 1.61e-10 Hip circumference adjusted for BMI; TGCT cis rs6671200 1.000 rs71654419 chr1:95664497 C/G cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT trans rs10435719 0.902 rs4840599 chr8:11805380 C/T cg15556689 chr8:8085844 FLJ10661 -0.75 -7.0 -0.53 1.39e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs11031096 0.738 rs2923950 chr11:4042069 G/C cg18678763 chr11:4115507 RRM1 0.36 4.7 0.39 6.93e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2589561 0.830 rs1612986 chr10:9064716 T/C cg08738443 chr10:8487762 NA 0.36 4.74 0.39 5.7e-6 Asthma; TGCT cis rs10779751 0.649 rs1318348 chr1:11130418 A/G cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs116095464 0.558 rs6555055 chr5:226160 A/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs319204 0.761 rs319142 chr5:146305665 T/C cg25021259 chr5:146258546 PPP2R2B 0.37 4.54 0.38 1.31e-5 Schizophrenia; TGCT cis rs9611519 0.929 rs13055800 chr22:41440424 G/A cg13695892 chr22:41940480 POLR3H -0.55 -4.9 -0.4 2.99e-6 Neuroticism; TGCT cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs727505 1.000 rs7777947 chr7:124436063 T/G cg23710748 chr7:124431027 NA -0.25 -4.59 -0.38 1.06e-5 Lewy body disease; TGCT cis rs4803468 0.934 rs8103531 chr19:41891974 C/T cg09537434 chr19:41945824 ATP5SL -0.9 -10.08 -0.67 8.25e-18 Height; TGCT cis rs9467711 0.606 rs67509210 chr6:26354100 G/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6500602 0.727 rs1477123 chr16:4560627 T/A cg08645402 chr16:4508243 NA 0.19 4.83 0.4 4e-6 Schizophrenia; TGCT cis rs7927771 0.864 rs4752999 chr11:47428565 C/T cg10139015 chr11:47448256 PSMC3 0.54 4.58 0.38 1.13e-5 Subjective well-being; TGCT cis rs4383453 0.539 rs11923120 chr3:123101592 A/G cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs3806843 1.000 rs3822346 chr5:140187322 C/T cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs3796352 1.000 rs7625448 chr3:53120766 C/A cg07884673 chr3:53033167 SFMBT1 0.53 5.68 0.45 9.21e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1218582 0.710 rs9793588 chr1:154878878 C/G cg09359103 chr1:154839909 KCNN3 -0.64 -11.6 -0.72 1.58e-21 Prostate cancer; TGCT cis rs4711350 0.765 rs756139 chr6:33755541 G/A cg13859433 chr6:33739653 LEMD2 -0.33 -4.93 -0.4 2.6e-6 Schizophrenia; TGCT cis rs68170813 0.559 rs77605964 chr7:106962948 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs137699 0.687 rs4821887 chr22:39756985 C/T cg01416388 chr22:39784598 NA -0.53 -4.59 -0.38 1.06e-5 IgG glycosylation; TGCT cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs3806843 0.576 rs246041 chr5:140331128 C/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7772486 0.790 rs2253654 chr6:146199445 T/C cg23711669 chr6:146136114 FBXO30 0.97 11.36 0.71 6.35e-21 Lobe attachment (rater-scored or self-reported); TGCT cis rs9534288 0.912 rs3736944 chr13:46619316 T/C cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs2204008 0.627 rs10878486 chr12:38148601 T/G cg13010199 chr12:38710504 ALG10B 0.65 5.15 0.42 1.01e-6 Bladder cancer; TGCT cis rs853679 0.517 rs1947863 chr6:28099344 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs9325144 0.647 rs11169222 chr12:39105210 C/T cg26384229 chr12:38710491 ALG10B -0.57 -5.29 -0.43 5.23e-7 Morning vs. evening chronotype; TGCT cis rs523522 0.962 rs4767905 chr12:120930835 C/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs7914558 0.966 rs11191438 chr10:104637864 C/G cg15744005 chr10:104629667 AS3MT -0.4 -5.04 -0.41 1.59e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs912057 0.695 rs1294419 chr6:6742549 C/G cg06612196 chr6:6737390 NA 0.36 4.79 0.4 4.59e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs6089829 0.962 rs4809456 chr20:61660849 C/A cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg08280861 chr8:58055591 NA 0.52 5.82 0.46 4.78e-8 Developmental language disorder (linguistic errors); TGCT cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT trans rs7726839 0.540 rs7558 chr5:660491 C/T cg11887960 chr12:57824829 NA 1.14 9.02 0.63 2.9e-15 Obesity-related traits; TGCT cis rs12926788 0.640 rs73551577 chr16:24845143 G/A cg06028605 chr16:24865363 SLC5A11 0.42 4.63 0.38 9.1e-6 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4372836 0.729 rs55785599 chr2:29087814 C/A cg09522027 chr2:28974177 PPP1CB 0.67 6.91 0.53 2.25e-10 Body mass index; TGCT cis rs586688 1.000 rs635979 chr1:201637811 C/T cg22851694 chr1:202075546 NA -0.37 -4.47 -0.37 1.76e-5 Obesity-related traits; TGCT cis rs295140 1.000 rs4516413 chr2:201163920 T/C cg04283868 chr2:201171347 SPATS2L 0.63 6.39 0.5 3.03e-9 QT interval; TGCT cis rs9443645 0.901 rs2174742 chr6:79610101 G/T cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs33794 0.901 rs28288 chr3:45290007 C/T cg18645101 chr3:44551900 NA 0.56 4.93 0.4 2.55e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT trans rs6089829 0.962 rs6122347 chr20:61661866 C/T cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg10802521 chr3:52805072 NEK4 0.73 9.39 0.64 3.73e-16 Bipolar disorder; TGCT cis rs9325144 0.560 rs10506127 chr12:39126686 C/G cg13010199 chr12:38710504 ALG10B -0.55 -5.02 -0.41 1.73e-6 Morning vs. evening chronotype; TGCT cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs875971 0.660 rs3857686 chr7:66036191 C/T cg00343986 chr7:65444356 GUSB -0.24 -5.29 -0.43 5.43e-7 Aortic root size; TGCT cis rs2338224 1.000 rs6859727 chr5:71742622 T/C cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs2832191 0.692 rs2776240 chr21:30310639 C/T cg08807101 chr21:30365312 RNF160 0.62 5.89 0.47 3.33e-8 Dental caries; TGCT cis rs72634258 0.503 rs72632055 chr1:7835774 T/G cg26816564 chr1:7831052 VAMP3 0.98 7.19 0.54 5.47e-11 Inflammatory bowel disease; TGCT cis rs922182 0.557 rs4776662 chr15:64203562 G/A cg02919090 chr15:64263738 DAPK2 -0.38 -6.93 -0.53 2.07e-10 Blood protein levels; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg25703541 chr22:24373054 LOC391322 -0.89 -10.45 -0.68 1.02e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4689592 0.554 rs66925245 chr4:7071999 C/T cg25660036 chr4:7070649 GRPEL1 0.6 4.78 0.39 4.9100000000000004e-06 Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs36028444 chr4:98968635 G/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4566357 0.615 rs12618793 chr2:227909552 T/C cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.92e-7 Coronary artery disease; TGCT cis rs514406 0.825 rs487453 chr1:53271225 T/C cg16325326 chr1:53192061 ZYG11B -0.7 -8.53 -0.61 4.4e-14 Monocyte count; TGCT cis rs8103278 1.000 rs7256192 chr19:46338492 G/A cg11657440 chr19:46296263 DMWD -0.6 -5.75 -0.46 6.51e-8 Coronary artery disease; TGCT cis rs317689 0.513 rs529268 chr12:69687051 G/A cg20891283 chr12:69753455 YEATS4 0.56 5.13 0.42 1.1e-6 Response to diuretic therapy; TGCT cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg03264133 chr6:25882463 NA 0.79 8.04 0.59 6e-13 Blood metabolite levels; TGCT cis rs36051895 0.659 rs2149555 chr9:5053743 C/T cg02405213 chr9:5042618 JAK2 -0.72 -9.64 -0.65 9.46e-17 Pediatric autoimmune diseases; TGCT cis rs1008375 0.932 rs9884565 chr4:17655096 A/G cg18681998 chr4:17616180 MED28 1.05 12.0 0.73 1.69e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4072980 0.545 rs12120737 chr1:38422544 C/T cg17077180 chr1:38461687 NA 0.49 4.78 0.39 4.89e-6 Coronary artery disease; TGCT cis rs2549003 1.000 rs2549002 chr5:131829578 C/A cg21138405 chr5:131827807 IRF1 -0.19 -4.85 -0.4 3.6e-6 Asthma (sex interaction); TGCT cis rs7208859 0.623 rs1061346 chr17:29114229 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs548987 0.529 rs1165165 chr6:25862466 C/T cg12310025 chr6:25882481 NA -0.62 -5.1 -0.42 1.24e-6 Homocysteine levels; TGCT cis rs10875746 0.855 rs10875728 chr12:48426392 T/G cg20731937 chr12:48336164 NA 0.67 5.15 0.42 9.92e-7 Longevity (90 years and older); TGCT cis rs1903068 0.886 rs1551644 chr4:55994266 A/T cg09978860 chr4:56023921 NA 0.58 6.38 0.5 3.16e-9 Endometriosis; TGCT cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs75686122 0.772 rs1079944 chr8:104555187 A/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs17376456 0.569 rs896729 chr5:93222178 A/G cg25358565 chr5:93447407 FAM172A -0.76 -6.04 -0.48 1.62e-8 Diabetic retinopathy; TGCT cis rs7829975 0.782 rs6990746 chr8:8547811 A/G cg15556689 chr8:8085844 FLJ10661 -0.71 -6.29 -0.49 4.97e-9 Mood instability; TGCT cis rs150268548 1 rs150268548 chr19:19494483 G/A cg03709012 chr19:19516395 GATAD2A 1.13 5.25 0.43 6.41e-7 LDL cholesterol change in response to fenofibrate in statin-treated type 2 diabetes;Response to fenofibrate (LDL cholesterol levels); TGCT cis rs4654899 1.000 rs10916921 chr1:21334542 C/T cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7027203 0.828 rs3996239 chr9:96611290 T/A cg14396892 chr9:96623032 NA -0.26 -5.47 -0.44 2.35e-7 DNA methylation (variation); TGCT cis rs2836974 0.545 rs2776311 chr21:40716885 A/G cg17971929 chr21:40555470 PSMG1 0.62 5.52 0.44 1.92e-7 Cognitive function; TGCT trans rs4650994 0.525 rs4076563 chr1:178516901 C/T cg05059571 chr16:84539110 KIAA1609 -0.54 -11.05 -0.7 3.43e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg11890956 chr21:40555474 PSMG1 -0.8 -7.75 -0.57 2.91e-12 Cognitive function; TGCT cis rs7043114 0.525 rs10820969 chr9:95106678 G/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.54 -0.45 1.72e-7 Height; TGCT cis rs7617773 0.779 rs11718329 chr3:48309828 C/G cg11946769 chr3:48343235 NME6 0.71 6.14 0.48 1.01e-8 Coronary artery disease; TGCT cis rs909674 0.818 rs8137426 chr22:39844350 T/G cg05872129 chr22:39784769 NA -0.99 -9.82 -0.66 3.44e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg21672276 chr3:44754072 ZNF502 -0.46 -5.12 -0.42 1.13e-6 Depressive symptoms; TGCT cis rs5769765 0.862 rs138870 chr22:50209737 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.04 -11.13 -0.71 2.21e-20 Schizophrenia; TGCT cis rs2439831 0.850 rs61390361 chr15:44159842 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs7666738 0.830 rs11944035 chr4:98931618 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs61990749 0.597 rs1006039 chr14:78263196 C/T cg02301378 chr14:78227641 SNW1;C14orf178 -0.6 -4.44 -0.37 1.93e-5 Fibroblast growth factor basic levels; TGCT cis rs35306767 0.951 rs55742421 chr10:961037 A/C cg26597838 chr10:835615 NA 0.75 10.39 0.68 1.43e-18 Eosinophil percentage of granulocytes; TGCT cis rs10488031 0.557 rs13231302 chr7:37104329 G/A cg06458904 chr7:36312573 EEPD1 0.58 4.79 0.39 4.72e-6 QT interval; TGCT cis rs651907 0.535 rs58658478 chr3:101511667 G/A cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.31 -0.49 4.5e-9 Colorectal cancer; TGCT trans rs916888 0.773 rs538628 chr17:44787313 G/C cg01341218 chr17:43662625 NA 1.04 7.82 0.57 1.97e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12477438 0.539 rs12999417 chr2:99865548 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.09 -16.29 -0.83 1.32e-32 Chronic sinus infection; TGCT cis rs6671200 0.831 rs79662819 chr1:95619804 C/T cg03123541 chr1:95699097 RWDD3 0.76 4.92 0.4 2.65e-6 Stearic acid (18:0) levels; TGCT cis rs9362426 1.000 rs1203156 chr6:88079694 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.4 4.49 0.37 1.6e-5 Depressive episodes in bipolar disorder; TGCT cis rs2832191 0.791 rs8134407 chr21:30476586 G/A cg24692254 chr21:30365293 RNF160 0.94 10.38 0.68 1.49e-18 Dental caries; TGCT cis rs826838 0.678 rs11182781 chr12:38610178 C/T cg26384229 chr12:38710491 ALG10B 0.9 8.06 0.59 5.32e-13 Heart rate; TGCT cis rs12765878 1.000 rs11191843 chr10:105648651 G/C cg11005552 chr10:105648138 OBFC1 0.44 7.69 0.57 4.01e-12 Coronary artery disease; TGCT cis rs6663390 0.510 rs61601393 chr1:208088684 C/G cg03990033 chr1:208084030 CD34 0.57 4.94 0.41 2.45e-6 Facial morphology (factor 18); TGCT cis rs10504229 0.953 rs114806125 chr8:58182416 C/T cg08280861 chr8:58055591 NA 0.32 4.49 0.37 1.63e-5 Developmental language disorder (linguistic errors); TGCT cis rs11792861 0.926 rs72607172 chr9:111876523 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.6 0.38 1.02e-5 Menarche (age at onset); TGCT cis rs2594989 1.000 rs388407 chr3:11320709 C/T cg00170343 chr3:11313890 ATG7 0.66 4.99 0.41 2.02e-6 Circulating chemerin levels; TGCT cis rs7666738 0.830 rs6532701 chr4:98745134 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.75 0.46 6.58e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs8072100 0.651 rs1912484 chr17:45443664 C/G cg08085267 chr17:45401833 C17orf57 -0.5 -5.63 -0.45 1.14e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7843479 0.582 rs7009693 chr8:21775314 C/T cg17168535 chr8:21777572 XPO7 0.72 7.06 0.54 1.02e-10 Mean corpuscular volume; TGCT cis rs9372253 1.000 rs7740028 chr6:110719180 A/G cg13266496 chr6:110720918 DDO -0.48 -5.81 -0.46 4.92e-8 Platelet distribution width; TGCT cis rs62392365 0.686 rs79070667 chr6:25194649 T/C cg16898833 chr6:26189333 HIST1H4D 0.95 4.57 0.38 1.17e-5 Schizophrenia;Intelligence (multi-trait analysis); TGCT cis rs4972806 0.849 rs2113561 chr2:177030925 G/A cg13092806 chr2:177043255 NA 0.55 4.72 0.39 6.25e-6 IgG glycosylation; TGCT cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7216064 0.953 rs8073510 chr17:65839210 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs11648796 0.680 rs11248946 chr16:768597 A/G cg07343612 chr16:622815 PIGQ -0.38 -5.37 -0.43 3.71e-7 Height; TGCT cis rs2172802 0.629 rs62304005 chr4:62494219 C/T cg04118610 chr4:62707027 LPHN3 0.43 4.65 0.39 8.53e-6 Partial epilepsies; TGCT cis rs1857353 1.000 rs1936359 chr1:75891016 T/C cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs17712049 0.908 rs62447154 chr7:48200369 C/A cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs2839186 0.500 rs13049893 chr21:47707054 C/T cg12379764 chr21:47803548 PCNT -0.49 -5.03 -0.41 1.71e-6 Testicular germ cell tumor; TGCT cis rs2836633 0.894 rs55955614 chr21:40037330 T/G cg05519781 chr21:40033154 ERG 0.69 6.81 0.52 3.81e-10 Coronary artery disease; TGCT cis rs7191439 0.858 rs8050715 chr16:88780923 C/G cg27087555 chr16:88793112 FAM38A -0.48 -5.53 -0.44 1.84e-7 Plateletcrit; TGCT cis rs2243480 0.803 rs13224048 chr7:65993766 G/A cg18252515 chr7:66147081 NA -1.21 -7.96 -0.58 9.08e-13 Diabetic kidney disease; TGCT cis rs2066819 1.000 rs744051 chr12:56667298 C/T cg26714650 chr12:56694279 CS 1.36 6.06 0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs3820068 0.705 rs11589076 chr1:15827027 C/T cg05660106 chr1:15850417 CASP9 1.18 13.63 0.77 2.04e-26 Systolic blood pressure; TGCT cis rs1670533 1.000 rs10084888 chr4:1053814 G/T cg20887711 chr4:1340912 KIAA1530 0.7 5.65 0.45 1.03e-7 Recombination rate (females); TGCT cis rs514406 0.505 rs269287 chr1:53168842 T/C cg22166914 chr1:53195759 ZYG11B 0.44 7.67 0.57 4.47e-12 Monocyte count; TGCT cis rs669446 0.533 rs7543520 chr1:44243866 T/C cg12908607 chr1:44402522 ARTN -0.61 -6.89 -0.53 2.55e-10 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs7647973 0.626 rs4855845 chr3:49687043 T/C cg05785598 chr3:49045655 WDR6 0.41 4.88 0.4 3.22e-6 Menarche (age at onset); TGCT cis rs7829975 0.742 rs882462 chr8:8678530 G/A cg06636001 chr8:8085503 FLJ10661 0.69 6.25 0.49 6.14e-9 Mood instability; TGCT trans rs7618501 0.633 rs35065728 chr3:50009176 T/C cg21659725 chr3:3221576 CRBN 0.76 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg10819733 chr22:24237672 NA -0.3 -5.01 -0.41 1.87e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9457247 0.967 rs377753 chr6:167389496 A/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs11249608 0.636 rs6888567 chr5:178449074 C/T cg01312482 chr5:178451176 ZNF879 0.56 5.45 0.44 2.62e-7 Pubertal anthropometrics; TGCT cis rs3803170 0.513 rs10774622 chr12:111833348 C/T cg10833066 chr12:111807467 FAM109A 0.36 5.3 0.43 5.16e-7 Mean corpuscular hemoglobin; TGCT cis rs9611565 0.592 rs5751129 chr22:42015765 C/T cg17554472 chr22:41940697 POLR3H 0.47 5.08 0.41 1.38e-6 Vitiligo; TGCT cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg16145915 chr7:1198662 ZFAND2A -0.55 -7.04 -0.53 1.17e-10 Longevity;Endometriosis; TGCT cis rs12908161 1.000 rs62019464 chr15:85294469 T/A cg12863693 chr15:85201151 NMB 0.41 4.89 0.4 3.05e-6 Schizophrenia; TGCT cis rs6815814 0.768 rs6851685 chr4:38893843 G/T cg02016764 chr4:38805732 TLR1 -0.28 -4.45 -0.37 1.92e-5 Breast cancer; TGCT cis rs1008375 0.931 rs2109519 chr4:17695453 A/G cg18681998 chr4:17616180 MED28 0.76 7.09 0.54 8.93e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs250677 0.687 rs2963484 chr5:148451127 A/T cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs1536827 0.541 rs11592587 chr10:135363653 G/A cg14503168 chr10:134895446 NA -0.55 -4.53 -0.38 1.36e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs5022636 0.525 rs7539584 chr1:151182953 C/T cg12798035 chr1:150981329 FAM63A;PRUNE -0.41 -4.55 -0.38 1.25e-5 Gut microbiota (functional units); TGCT cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6570726 0.620 rs367693 chr6:145815949 G/A cg13319975 chr6:146136371 FBXO30 -0.65 -5.77 -0.46 5.93e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7208487 0.684 rs12449852 chr17:37632088 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -6.04 -0.48 1.7e-8 Primary biliary cholangitis;Glomerular filtration rate in non diabetics (creatinine); TGCT cis rs4237845 0.715 rs4760340 chr12:58275176 A/T cg12615879 chr12:58013172 SLC26A10 -0.42 -4.91 -0.4 2.78e-6 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg23758822 chr17:41437982 NA 0.71 6.77 0.52 4.56e-10 Menopause (age at onset); TGCT cis rs9419702 0.538 rs4074772 chr10:133540006 A/T cg04492858 chr10:133558786 NA 0.58 6.24 0.49 6.34e-9 Survival in rectal cancer; TGCT cis rs13064411 0.735 rs9875025 chr3:113147552 T/C cg18753928 chr3:113234510 CCDC52 -0.69 -5.23 -0.43 6.83e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2836974 0.565 rs34304022 chr21:40579619 G/A cg11644478 chr21:40555479 PSMG1 0.8 5.92 0.47 2.9e-8 Cognitive function; TGCT cis rs11711311 1.000 rs3806641 chr3:113465761 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs4689592 0.583 rs6823154 chr4:7078145 C/T cg26116260 chr4:7069785 GRPEL1 0.98 9.1 0.63 1.91e-15 Monocyte percentage of white cells; TGCT cis rs4664308 1.000 rs16844715 chr2:160915106 A/G cg03641300 chr2:160917029 PLA2R1 0.25 6.42 0.5 2.63e-9 Idiopathic membranous nephropathy; TGCT cis rs2010099 0.583 rs112519474 chr3:124315623 G/A cg04915618 chr3:124304960 KALRN 0.51 4.62 0.38 9.44e-6 Thyroid peroxidase antibody levels; TGCT cis rs9916302 0.706 rs649180 chr17:37464959 A/C cg07936489 chr17:37558343 FBXL20 0.84 6.16 0.48 9.3e-9 Glomerular filtration rate (creatinine); TGCT cis rs1775715 0.707 rs2808088 chr10:32146150 A/G cg14930904 chr10:32216787 ARHGAP12 0.53 5.1 0.42 1.22e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs9443645 0.835 rs1044309 chr6:79646575 A/G cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs7044106 0.762 rs13291660 chr9:123392748 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.57 0.38 1.14e-5 Hip circumference adjusted for BMI; TGCT cis rs4595586 0.546 rs11609849 chr12:39258090 C/G cg26384229 chr12:38710491 ALG10B 0.66 5.41 0.44 3.13e-7 Morning vs. evening chronotype; TGCT cis rs6964587 1.000 rs2888851 chr7:91648341 G/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs763014 0.931 rs2071981 chr16:630025 C/G cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs7267979 0.702 rs449801 chr20:25491847 C/T cg21995068 chr20:25989032 LOC100134868 -0.43 -5.33 -0.43 4.55e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs427394 0.659 rs419128 chr5:6739791 G/A cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs155076 1.000 rs261406 chr13:21855854 G/A cg11317459 chr13:21872234 NA -1.33 -11.41 -0.72 4.71e-21 White matter hyperintensity burden; TGCT cis rs7589728 0.514 rs12465706 chr2:88467459 C/A cg04511125 chr2:88470314 THNSL2 0.83 6.93 0.53 2e-10 Plasma clusterin levels; TGCT cis rs734999 0.545 rs6666788 chr1:2567500 A/G cg18854424 chr1:2615690 NA -0.47 -5.38 -0.44 3.57e-7 Ulcerative colitis; TGCT cis rs6490294 0.796 rs7972112 chr12:112505182 T/A cg10833066 chr12:111807467 FAM109A 0.37 5.44 0.44 2.68e-7 Mean platelet volume; TGCT cis rs11098499 0.820 rs13122709 chr4:120555356 T/A cg09307838 chr4:120376055 NA 0.67 6.29 0.49 5.06e-9 Corneal astigmatism; TGCT cis rs10509586 0.522 rs17411458 chr10:91683749 G/A cg25278353 chr10:91717815 NA 0.43 5.05 0.41 1.55e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs4253772 0.550 rs9615951 chr22:46728056 C/A cg24881330 chr22:46731750 TRMU 1.0 4.89 0.4 3.03e-6 LDL cholesterol;Cholesterol, total; TGCT trans rs6089829 0.962 rs6089826 chr20:61668595 G/A cg17470723 chr8:74884337 TCEB1 0.77 7.4 0.55 1.82e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs4820539 0.966 rs2301554 chr22:23484254 A/C cg21100191 chr22:23484243 RTDR1 0.92 11.33 0.71 7.15e-21 Bone mineral density; TGCT cis rs6543140 0.964 rs6748390 chr2:103062175 A/G cg09003973 chr2:102972529 NA 0.57 4.8 0.4 4.41e-6 Blood protein levels; TGCT cis rs7914558 1.000 rs943036 chr10:104836047 T/C cg15744005 chr10:104629667 AS3MT -0.39 -4.69 -0.39 7.05e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10883723 1.000 rs10883723 chr10:104225832 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.75 7.48 0.56 1.19e-11 Allergic disease (asthma, hay fever or eczema); TGCT cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs11190604 0.767 rs4919459 chr10:102200371 C/T cg16342193 chr10:102329863 NA -0.41 -5.22 -0.42 7.22e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2933343 0.729 rs6790091 chr3:128608751 G/C cg11901034 chr3:128598214 ACAD9 -0.68 -6.63 -0.51 9.16e-10 IgG glycosylation; TGCT cis rs4665809 1.000 rs6709595 chr2:26259885 A/G cg25036284 chr2:26402008 FAM59B -0.55 -4.76 -0.39 5.33e-6 Gut microbiome composition (summer); TGCT cis rs523522 1.000 rs523522 chr12:121020250 A/T cg12219531 chr12:120966889 COQ5 0.8 7.08 0.54 9.41e-11 High light scatter reticulocyte count; TGCT cis rs78487399 0.908 rs12467420 chr2:43831150 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1775715 0.870 rs11008696 chr10:32218614 G/A cg14930904 chr10:32216787 ARHGAP12 0.48 4.53 0.38 1.39e-5 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs1865760 1.000 rs9348698 chr6:25929689 T/A cg17042849 chr6:26104293 HIST1H4C -0.5 -4.44 -0.37 2e-5 Height; TGCT cis rs12682352 0.602 rs6988939 chr8:8666916 C/T cg08975724 chr8:8085496 FLJ10661 0.52 4.46 0.37 1.84e-5 Neuroticism; TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg17178900 chr1:205818956 PM20D1 0.59 7.5 0.56 1.05e-11 Menarche (age at onset); TGCT cis rs9486719 1.000 rs2263192 chr6:96873037 C/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs9790314 0.586 rs16832279 chr3:161120483 C/T cg03342759 chr3:160939853 NMD3 -0.55 -5.7 -0.46 8.15e-8 Morning vs. evening chronotype; TGCT cis rs8180040 0.620 rs9845728 chr3:47103376 C/T cg27129171 chr3:47204927 SETD2 0.71 8.55 0.61 3.9e-14 Colorectal cancer; TGCT cis rs7772486 0.875 rs9390372 chr6:146363638 G/C cg05347473 chr6:146136440 FBXO30 0.56 5.42 0.44 2.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg20607798 chr8:58055168 NA 0.49 4.52 0.38 1.43e-5 Developmental language disorder (linguistic errors); TGCT cis rs10779751 1.000 rs4845982 chr1:11271576 T/C cg08854313 chr1:11322531 MTOR 0.94 8.51 0.61 4.75e-14 Body mass index; TGCT cis rs11785400 0.928 rs10100287 chr8:143734836 C/T cg10596483 chr8:143751796 JRK 0.56 6.02 0.48 1.87e-8 Schizophrenia; TGCT cis rs35146811 0.660 rs3779046 chr7:99779243 A/G cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs9357506 1.000 rs11962674 chr6:46320349 G/A cg21115430 chr6:46460003 NA -0.23 -4.53 -0.38 1.35e-5 Body mass index; TGCT cis rs2549003 1.000 rs10214312 chr5:131821866 T/G cg21138405 chr5:131827807 IRF1 0.19 4.79 0.39 4.76e-6 Asthma (sex interaction); TGCT cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg16414030 chr3:133502952 NA -0.52 -7.29 -0.55 3.17e-11 Iron status biomarkers; TGCT cis rs6089829 0.962 rs7273930 chr20:61666017 G/A cg08045932 chr20:61659980 NA 0.49 9.56 0.65 1.5e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs56804039 0.524 rs73190526 chr8:8423249 C/T cg14215082 chr8:9055850 NA 0.5 4.9 0.4 2.91e-6 Cervical cancer; TGCT cis rs9814567 0.752 rs13064209 chr3:134335993 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.75 6.75 0.52 4.98e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs62064224 0.554 rs9889352 chr17:30775761 T/C cg18200150 chr17:30822561 MYO1D 0.44 5.47 0.44 2.35e-7 Schizophrenia; TGCT cis rs9858542 0.953 rs34363169 chr3:49537712 G/A cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs4372836 0.580 rs6718662 chr2:29048758 G/C cg09522027 chr2:28974177 PPP1CB -0.67 -6.94 -0.53 1.97e-10 Body mass index; TGCT cis rs709400 0.633 rs1136165 chr14:103988180 G/T cg26031613 chr14:104095156 KLC1 -0.82 -8.3 -0.6 1.46e-13 Body mass index; TGCT cis rs9467711 0.516 rs1324088 chr6:25841122 C/T cg12310025 chr6:25882481 NA -0.68 -4.44 -0.37 2e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6598955 0.671 rs41285347 chr1:26644399 C/T cg04990556 chr1:26633338 UBXN11 0.62 4.6 0.38 1.04e-5 Obesity-related traits; TGCT cis rs612683 0.690 rs11166440 chr1:100808363 C/T cg06223162 chr1:101003688 GPR88 -0.32 -5.19 -0.42 8.46e-7 Breast cancer; TGCT cis rs10489202 1.000 rs66950781 chr1:168018779 C/A cg24449463 chr1:168025552 DCAF6 -0.42 -4.46 -0.37 1.85e-5 Schizophrenia; TGCT cis rs7221595 0.825 rs71366590 chr17:4006685 T/A cg09580393 chr17:4869866 SPAG7 -0.38 -4.46 -0.37 1.83e-5 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; TGCT cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11077998 0.933 rs7215465 chr17:80532532 C/T cg10255544 chr17:80519551 FOXK2 0.23 4.44 0.37 1.96e-5 Reticulocyte fraction of red cells; TGCT cis rs793571 0.502 rs395601 chr15:59063196 G/C cg05156742 chr15:59063176 FAM63B 0.55 5.18 0.42 8.61e-7 Schizophrenia; TGCT cis rs10927875 0.541 rs1048245 chr1:16341354 T/G cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs6735179 0.916 rs4143566 chr2:1771399 G/C cg08534653 chr2:1747700 PXDN 0.55 4.49 0.37 1.62e-5 Response to antipsychotic treatment; TGCT cis rs7809950 1.000 rs10243340 chr7:107090955 A/G cg23024343 chr7:107201750 COG5 -0.36 -5.63 -0.45 1.12e-7 Coronary artery disease; TGCT cis rs829880 0.789 rs1096146 chr12:98850966 A/G cg25150519 chr12:98850993 NA 0.62 6.22 0.49 7e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs12579753 0.917 rs10862361 chr12:82197946 T/C cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs10779751 0.690 rs910661 chr1:11130116 C/A cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs2016266 0.964 rs1609474 chr12:53676814 C/T cg16917193 chr12:54089295 NA -0.59 -4.76 -0.39 5.29e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs7647973 0.593 rs62262730 chr3:49808274 T/G cg05785598 chr3:49045655 WDR6 -0.42 -4.98 -0.41 2.06e-6 Menarche (age at onset); TGCT cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg19774624 chr17:42201019 HDAC5 -0.87 -10.63 -0.69 3.81e-19 Total body bone mineral density; TGCT cis rs6940638 0.956 rs12203454 chr6:27031100 C/T cg16898833 chr6:26189333 HIST1H4D 0.71 5.34 0.43 4.2e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs6854594 chr4:99065312 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs317689 0.918 rs689415 chr12:69738139 A/G cg20891283 chr12:69753455 YEATS4 -0.56 -4.6 -0.38 1.03e-5 Response to diuretic therapy; TGCT cis rs11718455 0.960 rs11929518 chr3:44016874 A/G cg08738300 chr3:44038990 NA 0.87 6.63 0.51 9.07e-10 Coronary artery disease; TGCT cis rs858239 1.000 rs156425 chr7:23309119 C/T cg05602783 chr7:23145260 KLHL7 0.57 4.81 0.4 4.26e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg06481639 chr22:41940642 POLR3H -0.72 -6.29 -0.49 4.98e-9 Vitiligo; TGCT cis rs5769707 0.616 rs135869 chr22:50008366 T/C cg05373962 chr22:49881684 NA -0.3 -5.03 -0.41 1.64e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg00786635 chr1:25594202 NA 0.53 5.64 0.45 1.11e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs77861329 1.000 rs13319566 chr3:52095555 C/G cg08692210 chr3:52188851 WDR51A 0.96 4.5 0.37 1.54e-5 Macrophage inflammatory protein 1b levels; TGCT cis rs477895 0.713 rs882146 chr11:63976699 G/A cg23719950 chr11:63933701 MACROD1 -0.7 -5.87 -0.47 3.66e-8 Mean platelet volume; TGCT cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg20276088 chr3:133502917 NA -0.27 -5.79 -0.46 5.51e-8 Iron status biomarkers; TGCT cis rs80282103 0.867 rs12241632 chr10:1069070 A/T cg08668510 chr10:1095578 IDI1 1.07 5.19 0.42 8.23e-7 Glomerular filtration rate (creatinine); TGCT trans rs3780486 0.846 rs4584234 chr9:33147479 G/A cg04842962 chr6:43655489 MRPS18A 1.17 14.6 0.8 1.07e-28 IgG glycosylation; TGCT cis rs950169 1.000 rs11638297 chr15:84782417 A/C cg17173187 chr15:85201210 NMB 0.44 4.71 0.39 6.46e-6 Schizophrenia; TGCT cis rs651907 0.535 rs12633089 chr3:101528763 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.86 0.4 3.51e-6 Colorectal cancer; TGCT cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg09436375 chr6:42928200 GNMT -0.4 -5.21 -0.42 7.49e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1609391 0.543 rs9881139 chr3:136634040 A/G cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs1865760 0.566 rs9366634 chr6:26072396 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.45 0.56 1.39e-11 Height; TGCT cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg10560079 chr2:191398806 TMEM194B 0.37 5.19 0.42 8.16e-7 Pulse pressure; TGCT cis rs4642101 0.793 rs13320486 chr3:12822069 C/A cg05775895 chr3:12838266 CAND2 0.79 8.91 0.62 5.38e-15 QRS complex (12-leadsum); TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg21548813 chr6:291882 DUSP22 -0.71 -7.45 -0.56 1.36e-11 Menopause (age at onset); TGCT cis rs6938 0.534 rs12904897 chr15:75217686 A/G cg09165964 chr15:75287851 SCAMP5 0.55 5.23 0.42 7.05e-7 Breast cancer; TGCT cis rs3734905 1.000 rs4716364 chr6:169949322 A/G cg05229362 chr6:169789120 NA 0.47 4.63 0.38 9.18e-6 HIV-1 control; TGCT cis rs7772486 0.558 rs9497403 chr6:146054695 T/G cg23711669 chr6:146136114 FBXO30 -0.73 -6.61 -0.51 1.04e-9 Lobe attachment (rater-scored or self-reported); TGCT trans rs916888 0.821 rs199507 chr17:44858855 A/G cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3820928 0.874 rs12467261 chr2:227888838 T/C cg11843606 chr2:227700838 RHBDD1 -0.57 -5.23 -0.42 7.12e-7 Pulmonary function; TGCT cis rs12142240 0.698 rs58162700 chr1:46816659 T/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs9486715 0.867 rs2499774 chr6:97006581 C/G cg06623918 chr6:96969491 KIAA0776 -1.1 -14.65 -0.8 7.83e-29 Headache; TGCT cis rs7666738 0.830 rs6834014 chr4:98951431 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs751728 0.687 rs9357164 chr6:33761021 T/C cg13859433 chr6:33739653 LEMD2 -0.33 -5.78 -0.46 5.71e-8 Crohn's disease; TGCT cis rs319204 0.885 rs488072 chr5:146280390 A/G cg25021259 chr5:146258546 PPP2R2B 0.36 4.6 0.38 1.01e-5 Schizophrenia; TGCT cis rs9682041 0.808 rs9875109 chr3:170064776 A/G cg07589077 chr3:170072950 NA -0.31 -5.48 -0.44 2.3e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs6912958 0.781 rs2268993 chr6:88184111 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.54 -5.23 -0.43 7.03e-7 Monocyte percentage of white cells; TGCT cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg03517284 chr6:25882590 NA -0.47 -4.73 -0.39 5.95e-6 Height; TGCT cis rs67072384 0.818 rs2291293 chr11:72470653 C/T cg03713592 chr11:72463424 ARAP1 -1.01 -5.04 -0.41 1.59e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs9993613 0.808 rs1518489 chr4:73429638 C/T cg15102770 chr4:73434591 ADAMTS3 0.5 4.68 0.39 7.41e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs12220898 0.749 rs4838482 chr10:50477414 G/A cg06072769 chr10:50146962 WDFY4 0.35 4.5 0.37 1.56e-5 Inflammatory biomarkers; TGCT cis rs3617 0.625 rs2071042 chr3:52864584 A/G cg11645453 chr3:52864694 ITIH4 0.29 5.71 0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9487051 0.872 rs1111863 chr6:109611206 C/T cg01475377 chr6:109611718 NA 0.3 4.62 0.38 9.65e-6 Reticulocyte fraction of red cells; TGCT cis rs3733585 0.673 rs6840802 chr4:9965633 C/G cg11266682 chr4:10021025 SLC2A9 0.57 7.6 0.56 6.26e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs478304 0.934 rs574483 chr11:65515277 A/G cg27068330 chr11:65405492 SIPA1 0.75 7.57 0.56 7.2e-12 Acne (severe); TGCT cis rs644799 1.000 rs474442 chr11:95583995 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.95 11.54 0.72 2.27e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9972944 0.756 rs6504344 chr17:63756668 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.11 -0.42 1.18e-6 Total body bone mineral density; TGCT cis rs12620999 0.938 rs4575672 chr2:238070572 T/C cg23555395 chr2:238036564 NA -0.28 -4.8 -0.4 4.49e-6 Systemic lupus erythematosus; TGCT cis rs7267979 1.000 rs2258769 chr20:25276680 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10464366 0.544 rs4723824 chr7:39153698 T/C cg15212455 chr7:39170539 POU6F2 0.3 6.7 0.52 6.63e-10 IgG glycosylation; TGCT cis rs250677 0.687 rs250663 chr5:148453117 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs875971 0.638 rs801205 chr7:66022144 C/A cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs56104184 0.830 rs73061617 chr19:49350984 G/A cg17863274 chr19:49399704 TULP2 -0.51 -6.28 -0.49 5.21e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4699052 0.662 rs6533082 chr4:104241205 G/A cg16532752 chr4:104119610 CENPE -0.57 -5.72 -0.46 7.37e-8 Testicular germ cell tumor; TGCT cis rs9467773 1.000 rs6903973 chr6:26499942 C/A cg09904177 chr6:26538194 HMGN4 0.64 6.49 0.5 1.89e-9 Intelligence (multi-trait analysis); TGCT cis rs10927875 1.000 rs4307563 chr1:16313788 C/T cg21385522 chr1:16154831 NA -0.77 -8.44 -0.6 7.05e-14 Dilated cardiomyopathy; TGCT cis rs9300255 0.543 rs520088 chr12:123522150 C/G cg00376283 chr12:123451042 ABCB9 0.7 5.17 0.42 9.08e-7 Neutrophil percentage of white cells; TGCT cis rs2242116 0.833 rs6442038 chr3:46960742 A/G cg27129171 chr3:47204927 SETD2 0.65 6.2 0.49 7.6e-9 Birth weight; TGCT cis rs7607369 0.791 rs12468043 chr2:219354197 C/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs79349575 0.756 rs62078385 chr17:47045009 C/T cg26022315 chr17:47021804 SNF8 0.47 4.56 0.38 1.2e-5 Type 2 diabetes; TGCT cis rs7666738 0.830 rs9998582 chr4:98938949 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10782582 0.609 rs5745547 chr1:76378275 G/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.54 4.64 0.38 8.88e-6 Daytime sleep phenotypes; TGCT cis rs12367572 0.796 rs7979141 chr12:45282630 A/T cg04608330 chr12:45269318 NELL2 -0.64 -6.7 -0.52 6.46e-10 Gut microbiome composition (summer); TGCT cis rs11203032 0.831 rs10887921 chr10:90925667 T/G cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs9309473 0.687 rs7576824 chr2:73611281 C/T cg20560298 chr2:73613845 ALMS1 0.48 5.39 0.44 3.36e-7 Metabolite levels; TGCT cis rs6582630 0.519 rs4405392 chr12:38293661 A/C cg13010199 chr12:38710504 ALG10B 0.57 4.49 0.37 1.62e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs2692947 0.655 rs4605406 chr2:96583735 A/C cg23100626 chr2:96804247 ASTL 0.38 4.58 0.38 1.09e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg09177884 chr7:1199841 ZFAND2A -0.51 -4.89 -0.4 3.03e-6 Longevity;Endometriosis; TGCT cis rs950169 1.000 rs1848093 chr15:84755527 G/C cg17173187 chr15:85201210 NMB 0.47 5.23 0.42 7.11e-7 Schizophrenia; TGCT cis rs9303542 0.559 rs12946931 chr17:46614080 T/C cg25032089 chr17:46643351 HOXB3 0.58 5.48 0.44 2.23e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs8177253 1.000 rs8177247 chr3:133479499 T/G cg01448562 chr3:133502909 NA -0.33 -6.58 -0.51 1.16e-9 Iron status biomarkers; TGCT cis rs524023 0.958 rs2021860 chr11:64361384 G/T cg07733098 chr11:64478343 NRXN2 0.32 4.97 0.41 2.17e-6 Urate levels in obese individuals; TGCT cis rs68170813 0.641 rs12539895 chr7:107091849 C/A cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs735396 0.770 rs2464196 chr12:121435427 G/A cg15155738 chr12:121454335 C12orf43 0.52 4.56 0.38 1.19e-5 N-glycan levels; TGCT cis rs2576037 0.562 rs477826 chr18:44397649 A/G cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs6840360 0.533 rs4696297 chr4:152725838 T/G cg17479576 chr4:152424074 FAM160A1 0.46 4.83 0.4 3.88e-6 Intelligence (multi-trait analysis); TGCT cis rs4843185 0.637 rs4143866 chr16:85716366 A/G cg02644593 chr16:85391138 NA 0.22 4.94 0.41 2.43e-6 Platelet distribution width; TGCT cis rs42648 0.935 rs42660 chr7:89982522 C/T cg25739043 chr7:89950458 NA -0.65 -6.22 -0.49 6.96e-9 Homocysteine levels; TGCT trans rs66573146 1.000 rs9942188 chr4:6984181 C/T cg07817883 chr1:32538562 TMEM39B 1.66 8.29 0.6 1.56e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs514406 0.505 rs395169 chr1:53174071 G/A cg25767906 chr1:53392781 SCP2 -0.46 -5.12 -0.42 1.14e-6 Monocyte count; TGCT cis rs7824557 0.689 rs10481454 chr8:11109303 C/G cg21775007 chr8:11205619 TDH -0.62 -5.42 -0.44 3.03e-7 Retinal vascular caliber; TGCT cis rs8180040 0.764 rs13084117 chr3:47183239 C/A cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg16414030 chr3:133502952 NA -0.51 -7.01 -0.53 1.32e-10 Iron status biomarkers; TGCT cis rs1008375 0.932 rs6841784 chr4:17626418 G/A cg10189774 chr4:17578691 LAP3 0.64 5.47 0.44 2.42e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs12472274 0.941 rs6748440 chr2:239100375 C/T cg17459225 chr2:239074497 NA 0.33 4.84 0.4 3.79e-6 Phospholipid levels (plasma); TGCT cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg05738196 chr6:26577821 NA -0.51 -4.92 -0.4 2.71e-6 Schizophrenia; TGCT cis rs7394190 0.688 rs76033784 chr10:75535970 A/G cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT trans rs1864982 1.000 rs560157 chr5:146314099 C/A cg14363954 chr9:139437479 NOTCH1 0.41 6.65 0.51 8.27e-10 Alcohol dependence; TGCT cis rs796364 0.906 rs1658810 chr2:200816382 C/T cg17644776 chr2:200775616 C2orf69 0.3 4.65 0.39 8.22e-6 Schizophrenia; TGCT cis rs6582630 0.554 rs8189625 chr12:38401177 C/T cg26384229 chr12:38710491 ALG10B -0.52 -4.52 -0.38 1.43e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg20607798 chr8:58055168 NA 0.65 5.46 0.44 2.47e-7 Developmental language disorder (linguistic errors); TGCT cis rs10791097 0.547 rs10791101 chr11:130739133 C/T cg14779329 chr11:130786720 SNX19 0.29 4.79 0.4 4.58e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs13424612 1.000 rs10206993 chr2:240900919 C/A cg26363272 chr2:240904871 NDUFA10 0.31 5.13 0.42 1.08e-6 Odorant perception (isobutyraldehyde); TGCT cis rs7666738 0.830 rs4699601 chr4:99034429 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4273100 0.688 rs12939947 chr17:19204531 A/T cg01534423 chr17:18965556 NA 0.8 7.29 0.55 3.17e-11 Schizophrenia; TGCT cis rs7655841 0.704 rs6824219 chr4:129876836 C/T cg26347359 chr4:129759716 PHF17 0.49 5.04 0.41 1.6e-6 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs35484700 1 rs35484700 chr4:55498781 CG/C cg02821500 chr4:54931072 CHIC2 0.48 4.71 0.39 6.54e-6 White blood cell count; TGCT cis rs12477438 0.834 rs6757019 chr2:99676936 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs2288884 1.000 rs72483951 chr19:52573682 G/C cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs9902453 0.967 rs55748380 chr17:28469782 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs8141529 0.748 rs7287918 chr22:29281710 G/A cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs2658782 0.654 rs2248524 chr11:93255715 G/A cg15737290 chr11:93063684 CCDC67 0.63 4.85 0.4 3.66e-6 Pulmonary function decline; TGCT cis rs9972944 0.691 rs7225471 chr17:63777913 T/C cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs367615 0.918 rs72797472 chr5:108881343 C/T cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs288326 0.561 rs76829215 chr2:183894452 A/G cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs4665809 1.000 rs10202478 chr2:26276049 T/C cg27170947 chr2:26402098 FAM59B -0.4 -4.58 -0.38 1.1e-5 Gut microbiome composition (summer); TGCT cis rs7726839 0.540 rs11738281 chr5:662547 T/C cg09021430 chr5:549028 NA -0.39 -5.35 -0.43 4.11e-7 Obesity-related traits; TGCT cis rs28595532 0.920 rs116205107 chr4:119730910 G/A cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs7178572 0.568 rs11854193 chr15:77458136 C/A cg22256960 chr15:77711686 NA -0.89 -8.95 -0.63 4.29e-15 Type 2 diabetes; TGCT cis rs6450176 0.625 rs56193151 chr5:53287790 C/T ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.65 -0.45 1.05e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7208859 0.623 rs9893422 chr17:29111715 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs921968 0.643 rs832802 chr2:219386899 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs11175492 0.528 rs10506537 chr12:65030890 G/A cg18624581 chr12:65153313 GNS -0.87 -4.86 -0.4 3.47e-6 Platelet count; TGCT cis rs9818758 0.607 rs34784192 chr3:49274823 G/T cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs13082711 0.522 rs6790344 chr3:27336531 G/C cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2455799 0.517 rs3846131 chr3:15932357 C/T cg12172478 chr3:16357591 RFTN1 -0.32 -4.66 -0.39 8.01e-6 Mean platelet volume; TGCT cis rs7772486 0.641 rs2777485 chr6:146334377 G/A cg23711669 chr6:146136114 FBXO30 0.68 6.39 0.5 3e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9486719 0.895 rs11152960 chr6:96900398 A/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7246657 0.943 rs9676967 chr19:37928089 G/C cg18154014 chr19:37997991 ZNF793 0.73 5.4 0.44 3.23e-7 Coronary artery calcification; TGCT cis rs2239547 0.618 rs2071041 chr3:52864693 T/G cg10802521 chr3:52805072 NEK4 -0.64 -6.2 -0.49 7.68e-9 Schizophrenia; TGCT cis rs1371867 0.513 rs1542812 chr8:101207064 G/A cg06002616 chr8:101225028 SPAG1 0.63 8.12 0.59 4.02e-13 Atrioventricular conduction; TGCT cis rs6594499 0.542 rs7722241 chr5:110460747 T/A cg04022379 chr5:110408740 TSLP 0.57 5.72 0.46 7.71e-8 Allergic disease (asthma, hay fever or eczema); TGCT cis rs425277 1.000 rs12401379 chr1:2058580 G/C cg03732007 chr1:2071316 PRKCZ 0.25 5.0 0.41 1.92e-6 Height; TGCT cis rs13315871 1.000 rs9864824 chr3:58394835 A/G cg12435725 chr3:58293450 RPP14 0.43 4.47 0.37 1.71e-5 Cholesterol, total; TGCT cis rs8177253 0.965 rs8177245 chr3:133479230 A/G cg16414030 chr3:133502952 NA -0.61 -9.47 -0.65 2.44e-16 Iron status biomarkers; TGCT cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg10295955 chr4:187884368 NA -0.95 -14.83 -0.8 2.95e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs9915657 0.660 rs982534 chr17:70081366 T/G cg06234051 chr17:70120541 SOX9 -0.24 -4.89 -0.4 3.05e-6 Thyroid hormone levels; TGCT cis rs7119038 0.774 rs2004781 chr11:118619253 C/T cg19308663 chr11:118741387 NA 0.29 5.39 0.44 3.41e-7 Sjögren's syndrome; TGCT cis rs7772486 0.686 rs1569540 chr6:146069112 A/G cg23711669 chr6:146136114 FBXO30 -0.88 -9.63 -0.65 1.01e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1005277 0.579 rs116912400 chr10:38479207 G/T cg25427524 chr10:38739819 LOC399744 -0.41 -8.54 -0.61 4.04e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2594989 0.733 rs6777022 chr3:11577636 G/A cg00170343 chr3:11313890 ATG7 -0.65 -4.91 -0.4 2.8e-6 Circulating chemerin levels; TGCT cis rs7172971 0.655 rs72727731 chr15:42342164 T/C cg05886115 chr15:42349113 NA 0.32 5.1 0.42 1.25e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg06035815 chr6:26189597 HIST1H4D 0.46 4.71 0.39 6.42e-6 Intelligence (multi-trait analysis); TGCT cis rs1018836 0.892 rs7819519 chr8:91565504 C/T cg16814680 chr8:91681699 NA -0.8 -8.57 -0.61 3.46e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7937682 1.000 rs4936661 chr11:111587495 G/A cg09085632 chr11:111637200 PPP2R1B 1.12 11.52 0.72 2.58e-21 Primary sclerosing cholangitis; TGCT cis rs9467773 0.626 rs6936006 chr6:26350565 A/G cg15659132 chr6:26577336 NA -0.55 -5.68 -0.45 9.13e-8 Intelligence (multi-trait analysis); TGCT cis rs6542838 0.704 rs12474283 chr2:99527310 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.41 -0.44 3.05e-7 Fear of minor pain; TGCT cis rs524281 1.000 rs489337 chr11:65854561 A/G cg00563793 chr11:65837595 PACS1 -0.53 -4.47 -0.37 1.71e-5 Electroencephalogram traits; TGCT cis rs11249608 0.548 rs17078991 chr5:178459426 A/C cg21905437 chr5:178450457 ZNF879 0.45 4.65 0.39 8.3e-6 Pubertal anthropometrics; TGCT cis rs2730245 1.000 rs2527199 chr7:158737113 G/A cg11984989 chr7:158649758 WDR60 -0.95 -8.47 -0.61 5.89e-14 Height; TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg14159672 chr1:205819179 PM20D1 0.63 7.94 0.58 1.04e-12 Menarche (age at onset); TGCT cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg03806693 chr22:41940476 POLR3H -1.14 -13.51 -0.77 4e-26 Vitiligo; TGCT trans rs17685 0.753 rs7804598 chr7:75702578 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT trans rs3780486 0.846 rs2209948 chr9:33138247 G/A cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT cis rs4665809 1.000 rs11678157 chr2:26321526 T/C cg25036284 chr2:26402008 FAM59B -0.58 -5.0 -0.41 1.92e-6 Gut microbiome composition (summer); TGCT cis rs7208859 0.673 rs12949860 chr17:29223032 A/G cg18442181 chr17:29233375 C17orf42 -0.76 -4.55 -0.38 1.27e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6876348 0.564 rs2577427 chr5:128311818 C/T cg25555059 chr5:128301488 SLC27A6 -0.29 -4.79 -0.4 4.64e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg07507251 chr3:52567010 NT5DC2 0.46 6.68 0.51 7.37e-10 Bipolar disorder; TGCT cis rs17221829 0.965 rs10830363 chr11:89458468 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.68 -0.39 7.38e-6 Anxiety in major depressive disorder; TGCT cis rs2299587 0.554 rs9325823 chr8:17735871 A/G cg01800426 chr8:17659068 MTUS1 0.54 4.84 0.4 3.83e-6 Economic and political preferences; TGCT cis rs7429990 0.896 rs34448818 chr3:47841312 G/A cg11946769 chr3:48343235 NME6 0.59 4.45 0.37 1.87e-5 Educational attainment (years of education); TGCT cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.49 -0.61 5.27e-14 Platelet count; TGCT cis rs7246657 1.000 rs7246657 chr19:37747108 C/T cg18154014 chr19:37997991 ZNF793 -0.68 -4.69 -0.39 6.97e-6 Coronary artery calcification; TGCT cis rs473651 0.837 rs563458 chr2:239345613 T/A cg18131467 chr2:239335373 ASB1 1.02 15.1 0.8 7.25e-30 Multiple system atrophy; TGCT cis rs3096299 0.748 rs3102339 chr16:89442711 C/T cg02187348 chr16:89574699 SPG7 0.52 4.83 0.4 3.86e-6 Multiple myeloma (IgH translocation); TGCT cis rs9858542 0.953 rs9821311 chr3:49543656 C/T cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs9914544 1.000 rs1737944 chr17:18840433 G/A cg26306683 chr17:18585705 ZNF286B 0.58 5.24 0.43 6.55e-7 Educational attainment (years of education); TGCT cis rs981844 0.712 rs921882 chr4:154752878 A/C cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs250677 0.917 rs36066 chr5:148419771 A/G cg23229984 chr5:148520753 ABLIM3 0.21 4.93 0.41 2.54e-6 Breast cancer; TGCT cis rs35306767 0.953 rs12354639 chr10:963681 G/A cg20503657 chr10:835505 NA 0.65 9.54 0.65 1.66e-16 Eosinophil percentage of granulocytes; TGCT cis rs4372836 0.964 rs4408686 chr2:28940526 T/C cg09522027 chr2:28974177 PPP1CB 0.59 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs514406 0.621 rs1930306 chr1:53195686 C/G cg25767906 chr1:53392781 SCP2 0.44 4.79 0.4 4.68e-6 Monocyte count; TGCT cis rs9926296 0.632 rs2011925 chr16:89814064 T/G cg03388025 chr16:89894329 SPIRE2 0.33 4.79 0.4 4.66e-6 Vitiligo; TGCT cis rs17001654 0.588 rs72655511 chr4:77021915 G/A cg22606062 chr4:77996244 CCNI -0.91 -4.56 -0.38 1.2e-5 BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.830 rs13124689 chr4:98961182 A/T cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11671005 0.735 rs12981875 chr19:58935130 A/C cg13877915 chr19:58951672 ZNF132 0.65 5.14 0.42 1.04e-6 Mean platelet volume; TGCT cis rs12477438 0.798 rs13412764 chr2:99583733 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs9425766 0.678 rs1951625 chr1:173836602 G/A cg07177756 chr1:173836307 SNORD75;SNORD78;ZBTB37;SNORD76;GAS5;SNORD77;SNORD44 0.53 4.67 0.39 7.65e-6 Life satisfaction; TGCT cis rs12497850 0.805 rs6446198 chr3:49007638 T/A cg06212747 chr3:49208901 KLHDC8B 0.61 5.5 0.44 2.06e-7 Parkinson's disease; TGCT cis rs2404602 0.622 rs11632670 chr15:76974055 A/G cg23625390 chr15:77176239 SCAPER -0.39 -4.93 -0.41 2.53e-6 Blood metabolite levels; TGCT cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg25767906 chr1:53392781 SCP2 0.5 5.85 0.46 4.15e-8 Monocyte count; TGCT cis rs6840360 0.615 rs12641441 chr4:152607623 A/G cg22705602 chr4:152727874 NA -0.32 -5.41 -0.44 3.12e-7 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs116834347 chr4:119774155 C/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg06634786 chr22:41940651 POLR3H 0.89 8.4 0.6 8.56e-14 Vitiligo; TGCT trans rs1974653 0.672 rs9606258 chr22:20119712 A/G cg08822737 chr17:71088851 SLC39A11 -0.95 -7.53 -0.56 8.93e-12 Schizophrenia; TGCT cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg18735214 chr6:43276756 CRIP3 -0.56 -4.88 -0.4 3.24e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9436747 0.770 rs6697315 chr1:65993556 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 5.21 0.42 7.71e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs17376456 0.877 rs10052428 chr5:93476530 T/C cg21475434 chr5:93447410 FAM172A 0.61 4.73 0.39 5.98e-6 Diabetic retinopathy; TGCT cis rs6693567 0.565 rs2264417 chr1:150368501 C/T cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs4372836 0.729 rs10174533 chr2:28968928 G/A cg09522027 chr2:28974177 PPP1CB -0.63 -6.25 -0.49 6.12e-9 Body mass index; TGCT cis rs9900497 0.569 rs2072327 chr17:19651482 G/T cg22552966 chr17:19620595 SLC47A2 -0.23 -5.65 -0.45 1.02e-7 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs9910055 0.762 rs2526021 chr17:42213347 G/A cg13607699 chr17:42295918 UBTF 0.84 7.76 0.57 2.72e-12 Total body bone mineral density; TGCT cis rs3096299 0.802 rs3102336 chr16:89442006 C/T cg06640241 chr16:89574553 SPG7 0.63 5.72 0.46 7.38e-8 Multiple myeloma (IgH translocation); TGCT cis rs7618915 1.000 rs59565798 chr3:52307169 G/A cg10802521 chr3:52805072 NEK4 -0.56 -5.89 -0.47 3.42e-8 Bipolar disorder; TGCT cis rs7954584 0.583 rs6486782 chr12:122359172 T/C cg21016266 chr12:122356598 WDR66 0.43 5.65 0.45 1.03e-7 Mean corpuscular volume; TGCT trans rs1005277 0.579 rs1740745 chr10:38520056 T/C cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs4563143 0.514 rs55727361 chr19:29300415 A/T cg04546413 chr19:29218101 NA 0.73 5.38 0.43 3.65e-7 Methadone dose in opioid dependence; TGCT cis rs7666738 0.800 rs2865987 chr4:99067852 A/C cg05340658 chr4:99064831 C4orf37 0.54 6.02 0.48 1.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs6988636 0.792 rs62521803 chr8:124152970 A/C cg23067535 chr8:124195133 FAM83A -0.38 -4.64 -0.38 8.89e-6 Urinary uromodulin levels; TGCT cis rs7772486 0.875 rs2748501 chr6:146312258 G/A cg13319975 chr6:146136371 FBXO30 -0.55 -4.82 -0.4 4.08e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7208859 0.673 rs11656845 chr17:29206164 G/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11585357 0.947 rs6684387 chr1:17611519 T/C cg08277548 chr1:17600880 PADI3 0.97 9.95 0.67 1.7e-17 Hair shape; TGCT cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs10490913 0.806 rs1857269 chr10:120172638 G/T cg23160142 chr10:120154512 NA 0.29 4.46 0.37 1.78e-5 Cancer; TGCT cis rs929354 0.742 rs62491945 chr7:156955580 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT trans rs2801405 0.584 rs1596653 chr10:100644548 G/A cg04906546 chr1:208317836 PLXNA2 -0.29 -6.86 -0.52 2.94e-10 Obesity-related traits; TGCT cis rs6977660 0.714 rs10252597 chr7:19791171 G/T cg05791153 chr7:19748676 TWISTNB -0.88 -5.05 -0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs10037670 0.557 rs2351481 chr5:153823460 G/A cg21964928 chr5:153872958 NA 0.26 4.69 0.39 6.96e-6 Behavioural disinhibition (generation interaction); TGCT cis rs72843506 0.591 rs74319100 chr17:20221392 A/G cg18979559 chr17:20280153 CCDC144C -0.62 -4.69 -0.39 7.2e-6 Schizophrenia; TGCT cis rs2637266 1.000 rs1907319 chr10:78337049 A/G cg18941641 chr10:78392320 NA -0.41 -5.11 -0.42 1.19e-6 Pulmonary function; TGCT cis rs9303401 0.659 rs62083368 chr17:56878062 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs7412746 0.658 rs12097963 chr1:150870450 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs986417 1.000 rs958504 chr14:60949740 G/A cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs6088580 0.634 rs1890002 chr20:32919219 A/G cg08999081 chr20:33150536 PIGU -0.27 -5.19 -0.42 8.22e-7 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs6532719 chr4:99043691 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg11861562 chr11:117069780 TAGLN 0.27 4.48 0.37 1.69e-5 Blood protein levels; TGCT trans rs2229238 0.911 rs59239860 chr1:154492107 G/T cg22838003 chr14:96730482 BDKRB1 0.4 6.66 0.51 8.03e-10 Coronary heart disease; TGCT cis rs9916302 0.904 rs11655531 chr17:37697959 T/C cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs10823500 0.640 rs7077538 chr10:71993094 T/G cg04118878 chr10:71993077 PPA1 0.61 5.61 0.45 1.23e-7 Blood protein levels; TGCT cis rs56104184 1.000 rs56104184 chr19:49370310 C/T cg15549821 chr19:49342101 PLEKHA4 -0.64 -8.96 -0.63 4.09e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs561341 0.505 rs28708703 chr17:30386845 C/G cg20587970 chr11:113659929 NA -0.98 -12.58 -0.75 6.87e-24 Hip circumference adjusted for BMI; TGCT cis rs6495367 1.000 rs1961579 chr15:79380516 G/A cg17916960 chr15:79447300 NA 0.37 5.24 0.43 6.57e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg27286337 chr10:134555280 INPP5A 0.39 4.73 0.39 6.02e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7582180 0.764 rs13001423 chr2:100925340 A/G cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.962 rs6062776 chr20:61663736 A/G cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs3820928 0.874 rs13423046 chr2:227901805 G/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs1799949 1.000 rs35070007 chr17:41316747 C/G cg23758822 chr17:41437982 NA -0.69 -6.78 -0.52 4.42e-10 Menopause (age at onset); TGCT cis rs7208859 0.623 rs9915546 chr17:29132144 G/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs61008539 0.815 rs6960062 chr7:884665 A/G cg15782153 chr7:917662 C7orf20 0.53 6.89 0.53 2.52e-10 Perceived unattractiveness to mosquitoes; TGCT cis rs6076065 0.748 rs2236023 chr20:23373043 A/C cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs2153535 0.580 rs4140586 chr6:8503192 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1867631 0.959 rs11208914 chr1:67049728 C/T cg13052034 chr1:66999238 SGIP1 0.59 5.02 0.41 1.75e-6 Menopause (age at onset); TGCT cis rs6426558 0.515 rs7521110 chr1:227384459 T/A cg10327440 chr1:227177885 CDC42BPA -0.61 -7.04 -0.53 1.14e-10 Neutrophil percentage of white cells; TGCT cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg00786635 chr1:25594202 NA 0.56 5.94 0.47 2.64e-8 Erythrocyte sedimentation rate; TGCT cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg11890956 chr21:40555474 PSMG1 -0.75 -7.38 -0.55 1.98e-11 Cognitive function; TGCT cis rs593982 0.920 rs72939198 chr11:65438079 G/A cg08755490 chr11:65554678 OVOL1 -1.26 -7.15 -0.54 6.6e-11 Atopic dermatitis; TGCT cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg06618935 chr21:46677482 NA -0.37 -5.58 -0.45 1.41e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6121246 0.697 rs6060446 chr20:30231637 T/C cg13852791 chr20:30311386 BCL2L1 0.74 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin; TGCT cis rs62244186 0.659 rs9311358 chr3:44538748 C/G cg15687855 chr3:44754131 ZNF502 -0.44 -5.15 -0.42 1e-6 Depressive symptoms; TGCT cis rs2806561 0.765 rs2806565 chr1:23507068 A/G cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs587847 0.737 rs28848193 chr15:37604276 C/G cg00216138 chr15:37171175 LOC145845 0.3 4.52 0.38 1.43e-5 Intraocular pressure; TGCT cis rs904251 0.523 rs2797796 chr6:37480886 T/C cg01843034 chr6:37503916 NA -0.56 -7.56 -0.56 7.84e-12 Cognitive performance; TGCT cis rs17376456 0.877 rs12109629 chr5:93359702 A/G cg21475434 chr5:93447410 FAM172A 0.6 4.73 0.39 6.08e-6 Diabetic retinopathy; TGCT cis rs11030122 0.702 rs10835340 chr11:3960420 A/G cg18678763 chr11:4115507 RRM1 0.46 5.77 0.46 5.94e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs10173297 0.686 rs6738533 chr2:3711919 G/T cg21484315 chr2:2712669 NA -0.38 -4.67 -0.39 7.61e-6 Response to inhaled corticosteroid treatment in asthma (change in FEV1); TGCT cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg10295955 chr4:187884368 NA -0.97 -15.16 -0.81 5.09e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.659 rs12150264 chr17:56939927 G/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs916888 0.821 rs199525 chr17:44847834 T/G cg05721485 chr17:44071124 MAPT 0.24 4.44 0.37 1.99e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs877282 0.853 rs12763400 chr10:763617 C/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs7666738 0.830 rs3907020 chr4:99038583 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12682352 0.602 rs11783966 chr8:8665147 A/G cg15556689 chr8:8085844 FLJ10661 -0.61 -5.28 -0.43 5.63e-7 Neuroticism; TGCT cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.53 5.07 0.41 1.42e-6 Electroencephalogram traits; TGCT cis rs397020 0.904 rs203547 chr20:1195245 T/A cg23117778 chr20:1206693 RAD21L1 0.84 10.65 0.69 3.32e-19 Multiple sclerosis; TGCT cis rs10788264 0.538 rs1998344 chr10:124030137 A/G cg09507567 chr10:124027408 NA 0.34 4.89 0.4 3.05e-6 Total body bone mineral density; TGCT cis rs36051895 0.594 rs7029244 chr9:5180961 A/C cg02405213 chr9:5042618 JAK2 -0.76 -10.76 -0.69 1.8e-19 Pediatric autoimmune diseases; TGCT cis rs6095298 0.595 rs752420 chr20:47435056 C/T cg12307787 chr20:48099359 KCNB1 0.43 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs10501293 0.746 rs4611191 chr11:43015676 C/G cg03447554 chr11:43094025 NA 0.44 6.29 0.49 4.98e-9 Cognitive performance; TGCT cis rs13326165 0.715 rs7643570 chr3:52373792 G/T cg07884673 chr3:53033167 SFMBT1 0.39 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs9910055 0.530 rs2269905 chr17:42294462 A/G cg19774624 chr17:42201019 HDAC5 -0.7 -7.47 -0.56 1.24e-11 Total body bone mineral density; TGCT cis rs8056742 0.642 rs11645050 chr16:85042212 A/C cg00229868 chr16:85520891 NA 0.41 4.89 0.4 3.09e-6 Amyotrophic lateral sclerosis; TGCT cis rs12220238 1.000 rs10824110 chr10:75968098 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT trans rs3780486 0.801 rs3780495 chr9:33125942 A/C cg04842962 chr6:43655489 MRPS18A 1.23 15.58 0.81 5.51e-31 IgG glycosylation; TGCT cis rs3820068 0.581 rs12385690 chr1:15932932 A/T cg05660106 chr1:15850417 CASP9 0.76 7.47 0.56 1.28e-11 Systolic blood pressure; TGCT cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg20887711 chr4:1340912 KIAA1530 0.91 8.31 0.6 1.41e-13 Longevity; TGCT cis rs250677 0.522 rs10050928 chr5:148353463 C/A cg18129178 chr5:148520854 ABLIM3 0.37 4.83 0.4 4.02e-6 Breast cancer; TGCT cis rs9581857 0.579 rs79904593 chr13:27996893 G/A cg22138327 chr13:27999177 GTF3A 0.85 5.88 0.47 3.55e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6570726 0.791 rs11759979 chr6:145918881 C/T cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg06238570 chr21:40685208 BRWD1 -0.8 -9.1 -0.63 1.9e-15 Cognitive function; TGCT cis rs6430585 0.527 rs1438303 chr2:136429857 C/T cg07169764 chr2:136633963 MCM6 0.97 8.68 0.61 1.89e-14 Corneal structure; TGCT cis rs7513165 0.935 rs4951316 chr1:204161490 C/T cg04791601 chr1:204159016 NA -0.26 -5.21 -0.42 7.68e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT trans rs12599106 0.839 rs3853177 chr16:34498532 A/G cg11235426 chr6:292522 DUSP22 -0.65 -6.78 -0.52 4.4e-10 Menopause (age at onset); TGCT cis rs902774 0.530 rs11834907 chr12:53350985 C/T cg16329197 chr12:53359506 NA -0.55 -4.62 -0.38 9.52e-6 Prostate cancer; TGCT cis rs6912958 0.781 rs7742965 chr6:88278196 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs6051080 1 rs6051080 chr20:25975674 A/G cg14121845 chr20:25566513 NINL 0.5 5.78 0.46 5.81e-8 Colorectal or endometrial cancer; TGCT cis rs7614311 0.681 rs10510903 chr3:63970192 C/G cg22134162 chr3:63841271 THOC7 -0.42 -5.73 -0.46 7.35e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs763014 0.932 rs2269560 chr16:682442 A/C cg09263875 chr16:632152 PIGQ 0.31 6.89 0.53 2.52e-10 Height; TGCT trans rs1496653 0.602 rs13091625 chr3:23606191 G/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.8 -8.29 -0.6 1.61e-13 Age at first birth; TGCT cis rs7666738 0.830 rs28729647 chr4:99059552 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg06697600 chr4:7070879 GRPEL1 -0.43 -4.46 -0.37 1.83e-5 Monocyte percentage of white cells; TGCT cis rs72901758 0.768 rs11650317 chr17:76251306 A/T cg25512537 chr17:76250053 NA 0.25 4.51 0.38 1.49e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs1008375 0.932 rs2302389 chr4:17661889 T/C cg18681998 chr4:17616180 MED28 0.92 10.26 0.68 2.88e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs617219 0.726 rs7717669 chr5:78452983 A/C cg23514016 chr5:78407564 BHMT 0.34 5.26 0.43 6.16e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7809950 1.000 rs2237677 chr7:107202502 A/C cg23024343 chr7:107201750 COG5 -0.3 -4.72 -0.39 6.34e-6 Coronary artery disease; TGCT trans rs3780486 0.846 rs10738905 chr9:33123627 A/G cg04842962 chr6:43655489 MRPS18A 1.23 15.36 0.81 1.81e-30 IgG glycosylation; TGCT trans rs1005277 0.541 rs2472177 chr10:38384015 T/G cg27523141 chr10:43048294 ZNF37B 0.71 8.32 0.6 1.35e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2688608 0.587 rs2894040 chr10:75478159 A/C cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs7224685 0.569 rs8082227 chr17:3991563 C/T cg09580393 chr17:4869866 SPAG7 -0.39 -4.49 -0.37 1.62e-5 Type 2 diabetes; TGCT cis rs9330316 0.654 rs9330320 chr2:110289984 C/G cg25199208 chr2:109402912 CCDC138 0.42 4.63 0.38 9.26e-6 Schizophrenia; TGCT cis rs4654899 0.931 rs58762579 chr1:21257831 G/A cg01072550 chr1:21505969 NA -0.49 -7.99 -0.58 7.94e-13 Superior frontal gyrus grey matter volume; TGCT trans rs7618501 0.633 rs11130228 chr3:50003246 C/T cg21659725 chr3:3221576 CRBN 0.75 9.11 0.63 1.79e-15 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs13141752 chr4:98893128 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.84 0.4 3.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4563143 0.663 rs2218396 chr19:29236392 C/T cg12756686 chr19:29218302 NA 0.65 6.06 0.48 1.52e-8 Methadone dose in opioid dependence; TGCT cis rs9467773 0.967 rs9461267 chr6:26525455 T/G cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.822 rs28512427 chr4:98919029 G/A cg05340658 chr4:99064831 C4orf37 0.53 6.12 0.48 1.13e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs60154123 0.505 rs77990373 chr1:210041111 T/C cg23283495 chr1:209979779 IRF6 0.67 4.99 0.41 1.96e-6 Coronary artery disease; TGCT cis rs2072499 0.932 rs2736613 chr1:156196016 T/C cg24450063 chr1:156163899 SLC25A44 1.2 14.13 0.79 1.31e-27 Testicular germ cell tumor; TGCT cis rs208520 0.690 rs851467 chr6:66802721 A/G cg07460842 chr6:66804631 NA -0.94 -9.91 -0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs78545713 1.000 rs11753610 chr6:26251601 C/T cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI 0.66 4.48 0.37 1.64e-5 Iron status biomarkers (total iron binding capacity); TGCT cis rs6912958 0.935 rs6454629 chr6:88165515 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.22 -0.49 7.06e-9 Monocyte percentage of white cells; TGCT cis rs6426558 0.537 rs6685823 chr1:227270835 A/G cg10327440 chr1:227177885 CDC42BPA 0.59 7.16 0.54 6.34e-11 Neutrophil percentage of white cells; TGCT cis rs9549367 0.789 rs9604040 chr13:113910611 A/G cg18105134 chr13:113819100 PROZ 0.32 5.3 0.43 5.06e-7 Platelet distribution width; TGCT trans rs62103177 0.561 rs891488 chr18:77637424 T/C cg05926928 chr17:57297772 GDPD1 -0.98 -9.6 -0.65 1.19e-16 Opioid sensitivity; TGCT cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg22105103 chr4:187893119 NA 0.34 4.86 0.4 3.41e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg13395646 chr4:1353034 KIAA1530 -0.38 -4.72 -0.39 6.28e-6 Obesity-related traits; TGCT cis rs950169 1.000 rs12915234 chr15:84758301 G/A cg12863693 chr15:85201151 NMB 0.38 4.66 0.39 8.17e-6 Schizophrenia; TGCT cis rs7666738 0.761 rs28758886 chr4:99059704 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10946940 0.965 rs10946935 chr6:27501345 T/C cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.6 -0.38 1.04e-5 Systemic lupus erythematosus; TGCT cis rs9297145 0.724 rs6958790 chr7:98774738 C/T cg05967295 chr7:98741636 SMURF1 -0.96 -12.36 -0.74 2.3e-23 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs79387448 0.745 rs7593444 chr2:103158561 G/A cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs62064224 0.614 rs9900089 chr17:30772577 C/T cg18200150 chr17:30822561 MYO1D 0.44 5.28 0.43 5.61e-7 Schizophrenia; TGCT cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs6088580 0.609 rs945674 chr20:32964247 G/C cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg23758822 chr17:41437982 NA 0.69 6.45 0.5 2.26e-9 Menopause (age at onset); TGCT cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg20637647 chr7:64974828 NA -0.9 -5.06 -0.41 1.45e-6 Diabetic kidney disease; TGCT cis rs2115536 1.000 rs2903105 chr15:80189523 C/G cg00225070 chr15:80189496 MTHFS 0.61 5.53 0.44 1.82e-7 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10465746 0.935 rs2389647 chr1:84403041 C/T cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs12510870 0.535 rs9997572 chr4:74438988 T/C cg05868023 chr4:75230803 EREG 0.55 4.97 0.41 2.18e-6 Iris color (b* coordinate); TGCT cis rs1401999 1.000 rs939337 chr3:183701147 G/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs4252435 0.614 rs6968468 chr7:142599997 T/C cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs7943191 0.805 rs12226821 chr11:62369018 C/G cg13298116 chr11:62369859 EML3;MTA2 0.6 7.18 0.54 5.56e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs1801251 1.000 rs991873 chr2:233711046 A/G cg25237894 chr2:233734115 C2orf82 -0.33 -5.94 -0.47 2.71e-8 Coronary artery disease; TGCT cis rs8111998 0.826 rs59427371 chr19:22766462 C/T cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs1857353 1.000 rs3899859 chr1:75884904 T/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7666738 0.716 rs28792413 chr4:99083707 G/A cg18180107 chr4:99064573 C4orf37 0.55 4.91 0.4 2.8e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.897 rs6446252 chr3:48911125 C/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs709400 0.663 rs9671911 chr14:103967343 T/C cg12935359 chr14:103987150 CKB -0.36 -5.64 -0.45 1.11e-7 Body mass index; TGCT cis rs2795502 1.000 rs2795502 chr10:43340662 G/A cg20628663 chr10:43360327 NA -0.44 -6.23 -0.49 6.74e-9 Blood protein levels; TGCT cis rs617219 0.671 rs1062326 chr5:78617534 A/C cg09550809 chr5:78407562 BHMT -0.39 -5.29 -0.43 5.32e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1008375 1.000 rs10019856 chr4:17615742 T/A cg18681998 chr4:17616180 MED28 1.08 12.03 0.73 1.45e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12136530 0.774 rs4912094 chr1:19762466 A/G cg18923740 chr1:19971790 NBL1 -0.35 -4.57 -0.38 1.16e-5 Lead levels in blood; TGCT cis rs7267979 1.000 rs2500404 chr20:25359758 A/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6582630 0.502 rs10880092 chr12:38262965 A/T cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs60871478 0.636 rs6976929 chr7:901382 C/T cg15782153 chr7:917662 C7orf20 0.54 4.91 0.4 2.8e-6 Cerebrospinal P-tau181p levels; TGCT cis rs3806843 0.966 rs3756341 chr5:140171194 C/T cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT trans rs531864 0.690 rs558922 chr2:169681749 C/T cg16341836 chr10:90641389 STAMBPL1 0.27 6.62 0.51 9.59e-10 Mitochondrial DNA levels; TGCT cis rs62244186 0.606 rs6798590 chr3:44556861 T/A cg10263370 chr3:44754102 ZNF502 -0.42 -4.81 -0.4 4.3e-6 Depressive symptoms; TGCT cis rs9914988 0.537 rs28448745 chr17:27188296 A/C cg20469991 chr17:27169893 C17orf63 0.67 4.48 0.37 1.69e-5 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs72717009 0.825 rs11810143 chr1:161480649 A/G cg23840854 chr1:161414152 NA -1.02 -6.12 -0.48 1.12e-8 Rheumatoid arthritis; TGCT cis rs11096990 0.634 rs6815855 chr4:39296546 C/A cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs6089829 0.962 rs4586690 chr20:61658595 G/T cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7255045 0.788 rs8111370 chr19:12948864 G/T cg23899408 chr19:12877188 HOOK2 -0.58 -4.66 -0.39 7.88e-6 Mean corpuscular volume; TGCT trans rs77457752 0.690 rs10123356 chr9:13912564 T/C cg23609682 chr1:3070786 PRDM16 0.48 6.96 0.53 1.78e-10 Breast cancer; TGCT cis rs617219 0.596 rs2131977 chr5:78613916 G/C cg09550809 chr5:78407562 BHMT -0.39 -5.43 -0.44 2.81e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT trans rs1005277 0.529 rs1780125 chr10:38531376 A/G cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs2439831 0.850 rs10438303 chr15:44016417 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs7666738 0.830 rs7657179 chr4:98948569 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2456568 0.709 rs1354765 chr11:93637776 G/T cg26875233 chr11:93583750 C11orf90 0.47 6.01 0.47 1.95e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1971762 0.712 rs7302232 chr12:53965423 A/T cg16917193 chr12:54089295 NA 0.91 9.39 0.64 3.77e-16 Height; TGCT cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 6.87 0.52 2.82e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs5750830 0.649 rs2413590 chr22:39790191 G/C cg02038168 chr22:39784481 NA -0.74 -6.02 -0.48 1.8e-8 Intelligence (multi-trait analysis); TGCT cis rs1784581 0.802 rs9365359 chr6:162423945 C/A cg17173639 chr6:162384350 PARK2 0.42 7.31 0.55 2.86e-11 Itch intensity from mosquito bite; TGCT cis rs12142240 0.738 rs41293277 chr1:46806550 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.95 0.47 2.58e-8 Menopause (age at onset); TGCT cis rs7659604 1.000 rs6816071 chr4:122665185 G/A cg19748678 chr4:122722346 EXOSC9 0.55 5.32 0.43 4.61e-7 Type 2 diabetes; TGCT cis rs295140 0.535 rs1975583 chr2:201225902 A/C cg04283868 chr2:201171347 SPATS2L 0.56 5.4 0.44 3.24e-7 QT interval; TGCT cis rs7698623 0.850 rs4693192 chr4:88797913 T/C cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs394563 0.591 rs6570963 chr6:149691355 T/G cg16235748 chr6:149772707 ZC3H12D 0.44 5.03 0.41 1.66e-6 Dupuytren's disease; TGCT cis rs7264396 0.528 rs6058370 chr20:34518592 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.69 -0.39 6.98e-6 Total cholesterol levels; TGCT cis rs4319547 0.774 rs7307233 chr12:123124301 C/G cg05707623 chr12:122985044 ZCCHC8 -0.65 -5.52 -0.44 1.89e-7 Body mass index; TGCT cis rs896854 0.517 rs10112447 chr8:95955701 C/T cg16049864 chr8:95962084 TP53INP1 -0.55 -6.07 -0.48 1.47e-8 Type 2 diabetes; TGCT cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg18252515 chr7:66147081 NA -1.22 -7.98 -0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs3125734 0.633 rs4979782 chr10:63998527 C/T cg05499367 chr10:63213510 TMEM26 -0.33 -4.45 -0.37 1.91e-5 Rheumatoid arthritis; TGCT cis rs62012628 0.527 rs12437868 chr15:79088460 T/C cg00639195 chr15:79103007 ADAMTS7 0.56 5.48 0.44 2.32e-7 Diastolic blood pressure; TGCT cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg07341220 chr16:1583899 IFT140;TMEM204 -0.3 -4.67 -0.39 7.76e-6 Coronary artery disease; TGCT cis rs477895 0.713 rs882146 chr11:63976699 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 6.8 0.52 4e-10 Mean platelet volume; TGCT cis rs11098499 0.866 rs12499602 chr4:120284387 T/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs9788682 1.000 rs12441354 chr15:78821016 G/A cg06917634 chr15:78832804 PSMA4 -0.7 -5.01 -0.41 1.83e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9858542 1.000 rs13085791 chr3:49721798 C/A cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7829975 0.623 rs10087493 chr8:8373557 A/G cg06636001 chr8:8085503 FLJ10661 -0.8 -8.09 -0.59 4.68e-13 Mood instability; TGCT cis rs7954584 0.531 rs11043271 chr12:122394921 A/C cg13699009 chr12:122356056 WDR66 0.29 5.7 0.46 8.39e-8 Mean corpuscular volume; TGCT cis rs9677476 0.516 rs765458 chr2:231990667 G/A cg27665808 chr2:232055229 NA 0.36 4.52 0.38 1.44e-5 Food antigen IgG levels; TGCT cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs12615966 0.872 rs11898434 chr2:105376704 G/A cg16465502 chr2:105461796 NA 0.78 5.01 0.41 1.83e-6 Pancreatic cancer; TGCT cis rs2307449 0.894 rs62020316 chr15:89787908 G/T cg24365117 chr15:89879190 POLG 0.33 4.51 0.38 1.49e-5 Menopause (age at onset); TGCT cis rs9322193 0.809 rs9479808 chr6:150072464 A/T cg13206674 chr6:150067644 NUP43 0.51 4.45 0.37 1.86e-5 Lung cancer; TGCT cis rs3741151 0.892 rs77127734 chr11:73018413 T/A cg17517138 chr11:73019481 ARHGEF17 0.94 4.48 0.37 1.66e-5 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs7843479 0.965 rs733543 chr8:21835465 A/G cg17168535 chr8:21777572 XPO7 0.63 5.8 0.46 5.08e-8 Mean corpuscular volume; TGCT cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg27286337 chr10:134555280 INPP5A 0.41 4.98 0.41 2.05e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11785693 0.862 rs11786186 chr8:4999059 G/C cg26367366 chr8:4980734 NA 0.54 4.44 0.37 1.97e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg05985448 chr10:134359359 INPP5A 0.23 4.96 0.41 2.24e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg26338869 chr17:61819248 STRADA -0.52 -4.8 -0.4 4.53e-6 Prudent dietary pattern; TGCT cis rs832540 0.966 rs33321 chr5:56206073 G/T cg24531977 chr5:56204891 C5orf35 -0.55 -5.68 -0.45 9.28e-8 Coronary artery disease; TGCT cis rs651907 0.514 rs11706494 chr3:101509475 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs72843506 0.586 rs113833946 chr17:19858906 T/C cg18979559 chr17:20280153 CCDC144C -0.59 -4.44 -0.37 1.99e-5 Schizophrenia; TGCT cis rs875971 0.862 rs801204 chr7:66022921 T/C cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs1403694 0.695 rs3821815 chr3:186434262 A/G cg12454167 chr3:186435060 KNG1 0.51 8.68 0.61 1.93e-14 Blood protein levels; TGCT cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs9788682 0.948 rs34664138 chr15:78831624 T/G cg06917634 chr15:78832804 PSMA4 -0.7 -4.86 -0.4 3.47e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs903263 0.901 rs6576961 chr1:84604712 T/C cg09664975 chr1:84543551 PRKACB 0.5 4.68 0.39 7.47e-6 Breast cancer (male); TGCT cis rs2016266 0.787 rs4520636 chr12:53752133 G/T cg16917193 chr12:54089295 NA 0.67 4.46 0.37 1.78e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs909002 0.772 rs7525618 chr1:32073766 C/T cg11573219 chr1:32083031 HCRTR1 -0.45 -5.87 -0.47 3.67e-8 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.686 rs702305 chr6:145973840 A/G cg13319975 chr6:146136371 FBXO30 0.53 4.9 0.4 2.91e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11098499 0.874 rs6851169 chr4:120117510 T/C cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs9816784 0.596 rs11185511 chr3:195835259 A/G cg14488913 chr3:195402182 SDHAP2 -0.34 -4.44 -0.37 1.96e-5 Mean corpuscular hemoglobin; TGCT cis rs950776 0.518 rs12915428 chr15:78823368 G/A cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs6088580 0.609 rs6058029 chr20:32969643 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg00149659 chr3:10157352 C3orf10 0.94 6.0 0.47 2e-8 Alzheimer's disease; TGCT cis rs595982 0.510 rs3826817 chr19:49401444 C/T cg11637076 chr19:49575188 KCNA7 -0.43 -5.31 -0.43 4.85e-7 Red cell distribution width; TGCT cis rs1865760 0.865 rs1436306 chr6:25948421 A/G cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT cis rs2404602 0.583 rs2139190 chr15:76555539 G/C cg22467129 chr15:76604101 ETFA -0.62 -8.06 -0.59 5.34e-13 Blood metabolite levels; TGCT cis rs6540559 0.673 rs7525951 chr1:210018306 C/T cg22029157 chr1:209979665 IRF6 -0.68 -4.88 -0.4 3.22e-6 Cleft lip with or without cleft palate; TGCT cis rs7552404 0.924 rs1146579 chr1:76209792 C/T cg10523679 chr1:76189770 ACADM -0.84 -9.27 -0.64 7.19e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7769051 0.803 rs12193474 chr6:133186168 T/C cg22852734 chr6:133119734 C6orf192 1.24 6.95 0.53 1.85e-10 Type 2 diabetes nephropathy; TGCT cis rs4665809 0.549 rs17527979 chr2:26428132 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.97 -6.06 -0.48 1.48e-8 Gut microbiome composition (summer); TGCT cis rs796364 1.000 rs4410273 chr2:200818258 T/C cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs10883723 0.810 rs7092622 chr10:104249919 T/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs9911578 0.935 rs9893351 chr17:57023326 G/A cg12560992 chr17:57184187 TRIM37 0.73 8.7 0.62 1.69e-14 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.851 rs2838858 chr21:46681093 T/A cg06618935 chr21:46677482 NA -0.37 -5.51 -0.44 1.98e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg12419862 chr22:24373484 LOC391322 -0.79 -8.17 -0.59 3e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs204693 1.000 rs204693 chr20:543638 C/T cg15180867 chr20:591076 TCF15 0.78 4.58 0.38 1.12e-5 Pursuit maintenance gain; TGCT cis rs3916 0.911 rs2239758 chr12:121162637 A/G cg21892295 chr12:121157589 UNC119B -0.23 -4.48 -0.37 1.69e-5 Urinary metabolites (H-NMR features); TGCT cis rs377070 0.934 rs309396 chr4:123614282 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.46 5.16 0.42 9.5e-7 Mosquito bite size; TGCT cis rs950169 0.840 rs72748702 chr15:84915246 A/G cg12863693 chr15:85201151 NMB 0.41 4.5 0.38 1.51e-5 Schizophrenia; TGCT cis rs12477438 0.765 rs1054042 chr2:99614396 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -4.86 -0.4 3.51e-6 Chronic sinus infection; TGCT cis rs4499344 0.730 rs12460624 chr19:33098042 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs10875746 0.903 rs11168427 chr12:48538979 A/G cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs6835098 0.924 rs1991727 chr4:174163169 A/G cg08422745 chr4:174089978 GALNT7 -0.83 -8.82 -0.62 9.04e-15 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs875971 1.000 rs11971949 chr7:65626014 A/G cg18876405 chr7:65276391 NA -0.33 -4.99 -0.41 1.97e-6 Aortic root size; TGCT cis rs4711350 0.765 rs943476 chr6:33750086 A/G cg13859433 chr6:33739653 LEMD2 -0.31 -4.49 -0.37 1.59e-5 Schizophrenia; TGCT trans rs7726839 0.540 rs3762951 chr5:662613 C/G cg25482853 chr8:67687455 SGK3 1.19 10.77 0.7 1.71e-19 Obesity-related traits; TGCT cis rs6484504 0.576 rs441975 chr11:31233351 C/T cg26647111 chr11:31128758 NA -0.34 -4.73 -0.39 5.88e-6 Red blood cell count; TGCT cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs11190604 1.000 rs2495753 chr10:102325640 C/T cg16342193 chr10:102329863 NA -0.43 -5.39 -0.44 3.43e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7833790 0.963 rs72686466 chr8:82758928 G/T cg27398817 chr8:82754497 SNX16 0.84 5.98 0.47 2.18e-8 Diastolic blood pressure; TGCT cis rs28595532 0.688 rs116580819 chr4:119767362 T/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs7572733 0.534 rs700662 chr2:198668751 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs2229238 0.911 rs4633282 chr1:154507899 T/C cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs7178572 0.568 rs11853460 chr15:77515319 C/T cg22256960 chr15:77711686 NA -0.87 -8.8 -0.62 9.73e-15 Type 2 diabetes; TGCT cis rs6977660 0.714 rs10228783 chr7:19789290 C/T cg05791153 chr7:19748676 TWISTNB 0.84 4.86 0.4 3.49e-6 Thyroid stimulating hormone; TGCT cis rs9549367 0.713 rs9549681 chr13:113829873 T/C cg18105134 chr13:113819100 PROZ -0.47 -8.24 -0.59 2.05e-13 Platelet distribution width; TGCT cis rs9644630 0.897 rs6984644 chr8:19363425 C/T cg01280390 chr8:19363452 CSGALNACT1 0.26 4.65 0.39 8.48e-6 Oropharynx cancer; TGCT cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg06481639 chr22:41940642 POLR3H 0.72 6.3 0.49 4.73e-9 Vitiligo; TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs11105298 0.891 rs1008764 chr12:89887649 T/C cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs3087591 1.000 rs12600974 chr17:29589360 A/G cg24425628 chr17:29625626 OMG;NF1 0.46 7.32 0.55 2.68e-11 Hip circumference; TGCT trans rs7726839 0.561 rs3915384 chr5:573395 G/T cg11887960 chr12:57824829 NA 0.95 7.66 0.57 4.58e-12 Obesity-related traits; TGCT cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg12310025 chr6:25882481 NA -0.53 -5.45 -0.44 2.63e-7 Blood metabolite levels; TGCT cis rs13191362 0.507 rs2023037 chr6:163120385 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.6 5.58 0.45 1.42e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6460942 0.643 rs80264734 chr7:12233800 T/A cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs79839061 0.610 rs11726280 chr4:864077 C/T cg15843217 chr4:699224 PCGF3 -0.63 -4.68 -0.39 7.3e-6 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg17775962 chr7:1200435 ZFAND2A 0.28 4.88 0.4 3.22e-6 Longevity;Endometriosis; TGCT cis rs8031584 0.958 rs8034856 chr15:31240957 T/C cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.29e-6 Huntington's disease progression; TGCT cis rs6951245 0.935 rs11766669 chr7:1063593 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.56 -0.38 1.19e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg12419862 chr22:24373484 LOC391322 0.81 8.51 0.61 4.7e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12188164 0.965 rs72717430 chr5:444502 T/C cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT trans rs2688608 0.592 rs10824031 chr10:75509273 C/T cg13918328 chr10:52500089 ASAH2B 0.67 6.83 0.52 3.39e-10 Inflammatory bowel disease; TGCT cis rs9443645 0.901 rs1354832 chr6:79613763 A/G cg05283184 chr6:79620031 NA 0.21 4.83 0.4 3.96e-6 Intelligence (multi-trait analysis); TGCT cis rs10744422 1.000 rs3852537 chr12:123361501 T/C cg25930673 chr12:123319894 HIP1R -0.85 -5.03 -0.41 1.69e-6 Schizophrenia; TGCT cis rs1362404 0.592 rs10163230 chr16:52000507 C/T cg03955530 chr16:52681474 NA 0.29 4.47 0.37 1.75e-5 Gut microbiota (bacterial taxa); TGCT cis rs2933343 0.729 rs789228 chr3:128601050 A/G cg11901034 chr3:128598214 ACAD9 -0.69 -6.55 -0.51 1.39e-9 IgG glycosylation; TGCT cis rs4911259 0.552 rs13037833 chr20:31459562 C/T cg13636640 chr20:31349939 DNMT3B -0.89 -9.82 -0.66 3.4e-17 Inflammatory bowel disease; TGCT cis rs3749237 0.595 rs3924462 chr3:49524236 T/G cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs892961 0.932 rs9916143 chr17:75409282 C/G cg05865280 chr17:75406074 SEPT9 -0.29 -6.99 -0.53 1.49e-10 Airflow obstruction; TGCT cis rs1371867 0.846 rs1788203 chr8:101303721 T/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs4820539 0.966 rs2301554 chr22:23484254 A/C cg14186256 chr22:23484241 RTDR1 1.02 13.65 0.77 1.86e-26 Bone mineral density; TGCT cis rs6089829 0.851 rs6122346 chr20:61661822 C/G cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7772486 0.875 rs9399572 chr6:146362945 T/G cg05347473 chr6:146136440 FBXO30 0.56 5.42 0.44 2.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6665290 0.835 rs7549465 chr1:227214399 A/C cg11404489 chr1:228071452 NA -0.19 -4.45 -0.37 1.87e-5 Myeloid white cell count; TGCT cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg03452623 chr4:187889614 NA -0.34 -5.17 -0.42 8.97e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs7726839 0.574 rs12517345 chr5:628294 G/A cg11887960 chr12:57824829 NA 1.14 9.28 0.64 6.87e-16 Obesity-related traits; TGCT cis rs4555082 0.834 rs2816653 chr14:105713973 A/G cg01266790 chr14:105781312 PACS2 0.53 4.47 0.37 1.76e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs9467711 0.606 rs28362606 chr6:26365586 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4478037 0.558 rs72854777 chr3:33069965 C/T cg19404215 chr3:33155277 CRTAP 1.04 4.98 0.41 2.12e-6 Major depressive disorder; TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg05457628 chr5:178986728 RUFY1 0.44 4.65 0.39 8.28e-6 Lung cancer; TGCT cis rs9467773 0.526 rs3734536 chr6:26365346 C/G cg15659132 chr6:26577336 NA -0.48 -4.81 -0.4 4.25e-6 Intelligence (multi-trait analysis); TGCT cis rs6543140 0.964 rs6736135 chr2:103064924 A/G cg09003973 chr2:102972529 NA 0.56 4.67 0.39 7.86e-6 Blood protein levels; TGCT cis rs7647973 0.710 rs11130208 chr3:49615624 G/T cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg06634786 chr22:41940651 POLR3H -0.87 -8.08 -0.59 4.79e-13 Vitiligo; TGCT cis rs919433 0.679 rs10203581 chr2:198515900 G/A cg00792783 chr2:198669748 PLCL1 0.54 4.8 0.4 4.55e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs3806843 0.576 rs405192 chr5:140324710 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.42 -5.37 -0.43 3.69e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs73198271 0.710 rs11779561 chr8:8679988 G/C cg06671706 chr8:8559999 CLDN23 -0.35 -4.46 -0.37 1.84e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs62283056 0.512 rs1079215 chr4:6282393 A/G cg14416269 chr4:6271139 WFS1 0.39 4.97 0.41 2.18e-6 Cisplatin-induced ototoxicity; TGCT cis rs10089 0.909 rs7732599 chr5:127370421 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT trans rs3790455 0.610 rs746527 chr1:156460511 C/T cg16443977 chr5:115884994 SEMA6A 0.41 7.14 0.54 6.85e-11 Migraine; TGCT cis rs1843834 0.898 rs12623277 chr2:225548072 T/G cg22455342 chr2:225449267 CUL3 0.74 7.25 0.55 3.94e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs77372450 0.551 rs11739081 chr5:157087119 C/G cg19063654 chr5:156516798 HAVCR2 -0.37 -4.52 -0.38 1.44e-5 Bipolar disorder (body mass index interaction); TGCT cis rs3820068 0.581 rs6692489 chr1:15928517 A/G cg05660106 chr1:15850417 CASP9 0.74 7.27 0.55 3.53e-11 Systolic blood pressure; TGCT cis rs1670533 1.000 rs28562028 chr4:1055115 G/A cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs12541335 0.590 rs11136002 chr8:22217082 C/T cg07298985 chr8:22133076 PIWIL2 0.34 5.09 0.42 1.28e-6 Hypertriglyceridemia; TGCT cis rs9322193 0.923 rs9800806 chr6:150061486 G/T cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg10150615 chr22:24372951 LOC391322 -0.8 -8.88 -0.62 6.18e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9993613 1.000 rs9993613 chr4:73476014 T/G cg15102770 chr4:73434591 ADAMTS3 -0.53 -4.95 -0.41 2.4e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs1865760 0.625 rs9393681 chr6:26008260 A/G cg17042849 chr6:26104293 HIST1H4C -0.65 -5.72 -0.46 7.7e-8 Height; TGCT cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.83e-5 Obesity-related traits; TGCT cis rs17445774 1.000 rs17445774 chr2:200859249 A/G cg17644776 chr2:200775616 C2orf69 -0.31 -4.96 -0.41 2.26e-6 LDL cholesterol to HDL cholesterol ratio; TGCT cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg10047753 chr17:41438598 NA 0.94 9.17 0.64 1.28e-15 Menopause (age at onset); TGCT cis rs1008375 0.898 rs7678654 chr4:17575376 T/G cg16339924 chr4:17578868 LAP3 0.83 7.37 0.55 2.06e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs5769707 0.967 rs2071904 chr22:50034477 C/T cg20744362 chr22:50050164 C22orf34 0.27 4.57 0.38 1.18e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10791323 0.581 rs2723608 chr11:133710149 A/G cg03690763 chr11:133734501 NA -0.31 -4.88 -0.4 3.13e-6 Childhood ear infection; TGCT cis rs76473307 1.000 rs1800902 chr20:57415455 C/T cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg23708337 chr7:1209742 NA 0.74 6.83 0.52 3.36e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6840360 0.934 rs6817058 chr4:152603865 T/C cg17479576 chr4:152424074 FAM160A1 -0.5 -5.3 -0.43 5.1e-7 Intelligence (multi-trait analysis); TGCT cis rs3125734 0.633 rs3852412 chr10:64050288 C/T cg09941381 chr10:64027924 RTKN2 -0.33 -4.9 -0.4 2.94e-6 Rheumatoid arthritis; TGCT trans rs7613875 0.620 rs34312088 chr3:50032133 C/T cg21659725 chr3:3221576 CRBN 0.7 7.95 0.58 9.9e-13 Body mass index; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.78 -0.39 4.78e-6 Prudent dietary pattern; TGCT cis rs4499344 0.921 rs12982788 chr19:33085501 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.7 -6.29 -0.49 5.01e-9 Mean platelet volume; TGCT cis rs10992471 0.528 rs7037194 chr9:95216745 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs11030122 0.702 rs4910866 chr11:3950554 A/T cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs2242194 0.816 rs11264296 chr1:154994750 T/C cg09359103 chr1:154839909 KCNN3 -0.45 -6.24 -0.49 6.41e-9 Schizophrenia; TGCT cis rs1577917 0.545 rs9294338 chr6:86474368 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.57 4.87 0.4 3.37e-6 Response to antipsychotic treatment; TGCT cis rs3806843 0.548 rs246052 chr5:140326413 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9517320 0.534 rs3858778 chr13:99172249 A/C cg20487152 chr13:99095054 FARP1 0.26 4.66 0.39 8.16e-6 Longevity; TGCT cis rs1053338 0.529 rs34003604 chr3:63747528 A/G cg22134162 chr3:63841271 THOC7 -0.3 -4.58 -0.38 1.12e-5 Breast cancer; TGCT cis rs1843834 0.539 rs2047135 chr2:225427302 G/C cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs11105298 0.891 rs4842653 chr12:89834113 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1538970 0.816 rs9727262 chr1:45998579 T/G cg05343316 chr1:45956843 TESK2 0.75 5.9 0.47 3.16e-8 Platelet count; TGCT cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs9549367 0.664 rs9549689 chr13:113848387 G/A cg00898013 chr13:113819073 PROZ -0.53 -6.94 -0.53 1.89e-10 Platelet distribution width; TGCT cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 5.25 0.43 6.47e-7 Height; TGCT cis rs9894429 0.646 rs6565609 chr17:79592267 G/A cg18240062 chr17:79603768 NPLOC4 0.56 4.92 0.4 2.67e-6 Eye color traits; TGCT cis rs11123694 1.000 rs11123694 chr2:109064563 C/T cg01745370 chr2:109065127 GCC2 0.43 4.93 0.4 2.55e-6 Mean platelet volume; TGCT cis rs1153858 1.000 rs1049508 chr15:45653592 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs9303401 0.659 rs62081314 chr17:56778328 A/G cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT trans rs877282 1.000 rs2004479 chr10:770854 G/A cg22713356 chr15:30763199 NA 1.21 10.47 0.69 8.99e-19 Uric acid levels; TGCT cis rs826838 0.904 rs11612004 chr12:39204282 G/A cg26384229 chr12:38710491 ALG10B 0.98 8.78 0.62 1.07e-14 Heart rate; TGCT cis rs2309752 1 rs2309752 chr2:100762169 T/A cg07810366 chr2:100720526 AFF3 -0.47 -8.0 -0.58 7.55e-13 Intelligence (multi-trait analysis); TGCT cis rs73198271 1.000 rs11775821 chr8:8609153 A/G ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.62 -0.38 9.34e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg25767906 chr1:53392781 SCP2 -0.61 -7.81 -0.57 2.07e-12 Monocyte count; TGCT cis rs941408 0.964 rs1736195 chr19:2786557 C/T cg06609049 chr19:2785107 THOP1 0.84 7.88 0.58 1.43e-12 Total cholesterol levels; TGCT cis rs8031584 0.752 rs2001686 chr15:31185772 G/A cg08109568 chr15:31115862 NA -0.35 -4.79 -0.4 4.66e-6 Huntington's disease progression; TGCT cis rs137603 0.644 rs137635 chr22:39720656 G/C cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.7 -0.39 6.73e-6 Primary biliary cholangitis; TGCT cis rs12682352 0.602 rs1473029 chr8:8668917 A/C cg15556689 chr8:8085844 FLJ10661 0.59 5.1 0.42 1.26e-6 Neuroticism; TGCT cis rs7582180 0.591 rs12991577 chr2:101010867 C/A cg14675211 chr2:100938903 LONRF2 0.5 4.69 0.39 6.95e-6 Intelligence (multi-trait analysis); TGCT cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg23982607 chr1:1823379 GNB1 -0.5 -7.65 -0.57 4.8e-12 Body mass index; TGCT cis rs7666738 0.800 rs10008654 chr4:98820498 C/A cg05340658 chr4:99064831 C4orf37 0.51 6.03 0.48 1.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 1.000 rs2592113 chr2:233669553 C/T cg08000102 chr2:233561755 GIGYF2 0.64 6.51 0.5 1.71e-9 Coronary artery disease; TGCT cis rs8062405 1.000 rs28403629 chr16:28854769 A/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs17122693 1.000 rs72679584 chr14:51092320 T/C cg04730355 chr14:51134070 SAV1 1.24 8.74 0.62 1.38e-14 Cognitive performance; TGCT cis rs7432375 0.966 rs6808312 chr3:136371504 C/T cg12473912 chr3:136751656 NA -0.34 -4.93 -0.41 2.55e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg00149659 chr3:10157352 C3orf10 0.94 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs4319547 1.000 rs10998 chr12:122989412 G/A cg05707623 chr12:122985044 ZCCHC8 -0.71 -5.67 -0.45 9.65e-8 Body mass index; TGCT cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs9916302 0.752 rs6503513 chr17:37561613 A/G cg15445000 chr17:37608096 MED1 -0.33 -4.64 -0.38 8.86e-6 Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.754 rs12711071 chr4:120240934 A/G cg09307838 chr4:120376055 NA 0.6 5.74 0.46 6.79e-8 Corneal astigmatism; TGCT trans rs1814175 0.817 rs4881645 chr11:49791168 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.46 -0.56 1.33e-11 Height; TGCT cis rs28785552 0.800 rs1971063 chr19:53232854 G/C cg10871876 chr19:53194124 ZNF83 0.55 7.66 0.57 4.65e-12 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg04389838 chr3:44770851 ZNF501 -0.37 -4.89 -0.4 3.12e-6 Depressive symptoms; TGCT cis rs12134133 1.000 rs7535532 chr1:207438336 C/T cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs6933660 0.646 rs6911456 chr6:151778934 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.73 7.65 0.57 4.75e-12 Menarche (age at onset); TGCT cis rs7589728 0.563 rs2292868 chr2:88475047 A/G cg04511125 chr2:88470314 THNSL2 -0.63 -4.98 -0.41 2.04e-6 Plasma clusterin levels; TGCT cis rs801193 1.000 rs4279493 chr7:66226620 C/T cg18876405 chr7:65276391 NA 0.35 5.2 0.42 8.09e-7 Aortic root size; TGCT trans rs7819412 0.715 rs35223712 chr8:11043926 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.64 -0.51 8.75e-10 Triglycerides; TGCT cis rs7666738 0.830 rs2865981 chr4:99031493 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs769267 0.965 rs8103496 chr19:19386015 A/G cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs425277 0.606 rs262664 chr1:2083537 G/C cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.46 -0.37 1.81e-5 Height; TGCT cis rs1205863 1.000 rs209813 chr6:11953633 A/G cg07106625 chr6:11870215 NA 0.48 4.72 0.39 6.15e-6 Disc degeneration (lumbar); TGCT cis rs977747 0.872 rs4926726 chr1:47679486 G/A cg03885399 chr1:47691550 TAL1 -0.4 -5.15 -0.42 1e-6 Body mass index; TGCT cis rs208520 1.000 rs72880045 chr6:66965232 A/C cg07460842 chr6:66804631 NA 0.83 7.52 0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs9467773 0.869 rs9295689 chr6:26455811 T/C cg02458000 chr6:26745757 NA 0.47 4.59 0.38 1.09e-5 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg07061783 chr6:25882402 NA -0.42 -4.51 -0.38 1.51e-5 Blood metabolite levels; TGCT cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg00149659 chr3:10157352 C3orf10 0.95 5.83 0.46 4.51e-8 Alzheimer's disease; TGCT cis rs875971 0.862 rs35378740 chr7:65987712 C/A cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT trans rs7618501 1.000 rs11130221 chr3:49819102 C/G cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs9790314 0.846 rs7636941 chr3:160993928 A/G cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs13040088 1.000 rs6090155 chr20:61527378 G/A cg12680822 chr20:61666554 NCRNA00029 0.28 4.45 0.37 1.87e-5 Menopause (age at onset); TGCT cis rs3617 0.625 rs7617468 chr3:52849549 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.5 -0.38 1.51e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6708331 0.517 rs12614547 chr2:70283971 T/A cg16435808 chr2:70475954 TIA1 0.57 4.54 0.38 1.31e-5 Obesity-related traits; TGCT cis rs5769765 0.908 rs9616376 chr22:50310829 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs10788264 0.652 rs9633732 chr10:124056473 G/T cg09507567 chr10:124027408 NA 0.37 5.32 0.43 4.71e-7 Total body bone mineral density; TGCT cis rs11614913 0.551 rs1867297 chr12:54396971 A/G cg16264616 chr12:54390824 NA 0.35 4.8 0.4 4.41e-6 Waist circumference adjusted for body mass index; TGCT cis rs9948 0.655 rs7568206 chr2:97393108 A/C cg01990225 chr2:97406019 LMAN2L -0.94 -5.33 -0.43 4.44e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg00684032 chr4:1343700 KIAA1530 0.22 4.82 0.4 4.11e-6 Obesity-related traits; TGCT cis rs1552244 0.572 rs6783705 chr3:10164783 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg18252515 chr7:66147081 NA -1.27 -7.73 -0.57 3.17e-12 Diabetic kidney disease; TGCT cis rs7208859 0.673 rs216420 chr17:28938508 C/T cg19761014 chr17:28927070 LRRC37B2 0.55 4.77 0.39 5.12e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs240764 0.621 rs6570930 chr6:101181258 C/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs4780401 0.609 rs7205994 chr16:11815964 C/T cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT trans rs1814175 0.692 rs1851873 chr11:49937767 A/G cg03929089 chr4:120376271 NA -0.59 -6.77 -0.52 4.5e-10 Height; TGCT cis rs13191362 1.000 rs13220048 chr6:163004325 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9549260 0.753 rs2297628 chr13:41233905 T/C cg21288729 chr13:41239152 FOXO1 0.69 4.87 0.4 3.31e-6 Red blood cell count; TGCT trans rs77457752 0.523 rs9696661 chr9:13901539 T/C cg23609682 chr1:3070786 PRDM16 0.51 6.81 0.52 3.8e-10 Breast cancer; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg14624950 chr17:62577106 SMURF2 -0.21 -4.73 -0.39 5.88e-6 Prudent dietary pattern; TGCT cis rs17331151 0.573 rs4687556 chr3:52890475 T/C cg27565382 chr3:53032988 SFMBT1 -0.45 -5.76 -0.46 6.25e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs151997 1.000 rs373030 chr5:50215836 G/A cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs116095464 0.867 rs7726582 chr5:215349 C/G cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs6752107 1.000 rs2241879 chr2:234183468 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.81 0.4 4.36e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs514406 0.536 rs878957 chr1:53197559 C/T cg16325326 chr1:53192061 ZYG11B -0.85 -11.44 -0.72 4.04e-21 Monocyte count; TGCT cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg00684032 chr4:1343700 KIAA1530 0.22 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs9902453 0.817 rs2617881 chr17:28063275 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.89 -0.53 2.55e-10 Coffee consumption (cups per day); TGCT cis rs2230307 0.572 rs514090 chr1:100563186 C/G cg24955406 chr1:100503596 HIAT1 0.75 5.13 0.42 1.1e-6 Carotid intima media thickness; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg01411255 chr17:61851458 DDX42;CCDC47 -0.74 -7.02 -0.53 1.26e-10 Prudent dietary pattern; TGCT cis rs9486719 1.000 rs11757063 chr6:96884886 C/T cg18709589 chr6:96969512 KIAA0776 -0.72 -5.27 -0.43 5.96e-7 Migraine;Coronary artery disease; TGCT cis rs8033133 0.678 rs7496110 chr15:25347013 A/G cg14481604 chr15:25334117 SNORD116-22 -0.27 -5.36 -0.43 3.96e-7 Blood osmolality (transformed sodium); TGCT cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg19635926 chr16:89946313 TCF25 0.25 4.53 0.38 1.39e-5 Skin colour saturation; TGCT cis rs1799949 0.930 rs2298861 chr17:41176831 G/A cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs12549902 0.966 rs4317621 chr8:41516581 A/G cg21772509 chr8:41503840 NKX6-3 0.85 9.35 0.64 4.7e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs7191700 0.673 rs12325495 chr16:11418328 C/T cg00044050 chr16:11439710 C16orf75 0.95 12.37 0.74 2.23e-23 Multiple sclerosis; TGCT cis rs9911578 1.000 rs6503870 chr17:56659018 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.629 rs11685406 chr2:100946638 A/G cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs453301 0.686 rs6601281 chr8:8911004 A/G cg15556689 chr8:8085844 FLJ10661 -0.64 -5.26 -0.43 6.09e-7 Joint mobility (Beighton score); TGCT cis rs600231 0.665 rs1784858 chr11:65222952 T/C cg11802864 chr11:65308245 LTBP3 0.45 4.64 0.38 8.62e-6 Bone mineral density; TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg08859206 chr1:53392774 SCP2 -0.49 -8.02 -0.58 6.87e-13 Monocyte count; TGCT cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg18230493 chr5:56204884 C5orf35 -0.66 -5.74 -0.46 6.99e-8 Initial pursuit acceleration; TGCT cis rs12908161 0.959 rs34342559 chr15:85331271 A/G cg12863693 chr15:85201151 NMB 0.42 4.95 0.41 2.38e-6 Schizophrenia; TGCT cis rs10782582 0.593 rs6675212 chr1:76230829 C/A cg03433033 chr1:76189801 ACADM -0.55 -6.04 -0.48 1.66e-8 Daytime sleep phenotypes; TGCT cis rs28595532 0.841 rs56046449 chr4:119769302 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs1171582 0.545 rs4948360 chr10:61521501 T/C cg23572703 chr10:62241191 NA -0.27 -4.64 -0.38 8.55e-6 Alopecia areata; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg14851468 chr5:179071604 C5orf60 -0.22 -4.49 -0.37 1.64e-5 Lung cancer; TGCT cis rs2204008 0.837 rs11519926 chr12:38348992 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.25 0.55 4e-11 Bladder cancer; TGCT cis rs7172809 0.573 rs74027549 chr15:77524761 A/G cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT cis rs17601876 0.843 rs17523541 chr15:51554844 G/A cg19946085 chr15:51559439 CYP19A1 -0.32 -4.84 -0.4 3.84e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs597539 0.518 rs35093305 chr11:68730729 A/G cg06112835 chr11:68658793 MRPL21 0.45 7.45 0.56 1.39e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs1864729 1.000 rs2053480 chr8:98278951 A/T cg08679828 chr8:102218111 ZNF706 1.1 7.71 0.57 3.56e-12 Estradiol plasma levels (breast cancer); TGCT cis rs1878931 0.582 rs27227 chr16:3429778 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.41 -0.5 2.7e-9 Body mass index (adult); TGCT cis rs4654899 0.931 rs10799671 chr1:21196764 C/T cg01072550 chr1:21505969 NA 0.5 7.93 0.58 1.08e-12 Superior frontal gyrus grey matter volume; TGCT cis rs4824093 0.535 rs73441802 chr22:50273916 G/A cg20569369 chr22:51173646 NA 0.29 4.84 0.4 3.86e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs13256369 0.760 rs7816171 chr8:8575835 T/C cg17143192 chr8:8559678 CLDN23 0.63 5.93 0.47 2.8e-8 Obesity-related traits; TGCT trans rs2749592 0.550 rs7081464 chr10:37883937 C/T cg17830980 chr10:43048298 ZNF37B 0.64 6.76 0.52 4.71e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs642803 1.000 rs557675 chr11:65566719 G/T cg27068330 chr11:65405492 SIPA1 -0.56 -5.03 -0.41 1.67e-6 Urate levels; TGCT cis rs13256369 1.000 rs885000 chr8:8568875 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.57 0.38 1.18e-5 Obesity-related traits; TGCT cis rs4654899 1.000 rs4654899 chr1:21410231 G/T cg01072550 chr1:21505969 NA -0.5 -8.04 -0.59 6.23e-13 Superior frontal gyrus grey matter volume; TGCT cis rs36051895 0.659 rs10974935 chr9:5050307 C/T cg02405213 chr9:5042618 JAK2 -0.78 -10.85 -0.7 1.1e-19 Pediatric autoimmune diseases; TGCT cis rs6988636 1.000 rs60362869 chr8:124189971 A/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1371867 0.875 rs1125706 chr8:101326739 T/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs7267979 1.000 rs2500418 chr20:25382268 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.73e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs9329221 0.905 rs6601451 chr8:10243681 C/G cg15556689 chr8:8085844 FLJ10661 -0.79 -7.35 -0.55 2.39e-11 Neuroticism; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.51 5.4 0.44 3.28e-7 Lymphocyte counts; TGCT cis rs7772486 0.875 rs2748501 chr6:146312258 G/A cg05347473 chr6:146136440 FBXO30 0.57 5.26 0.43 6.18e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.575 rs2955357 chr17:17946401 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.32 -0.6 1.37e-13 Total body bone mineral density; TGCT cis rs9796 0.835 rs2927062 chr15:41302687 A/G cg18705301 chr15:41695430 NDUFAF1 -0.45 -5.83 -0.46 4.59e-8 Menopause (age at onset); TGCT cis rs12042938 0.507 rs1765778 chr1:231732356 G/A cg04892437 chr1:231737901 TSNAX-DISC1 -0.42 -4.83 -0.4 3.98e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs11122272 0.735 rs2790882 chr1:231532783 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.64 5.95 0.47 2.5e-8 Hemoglobin concentration; TGCT cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs6815814 0.851 rs4274855 chr4:38777471 C/T cg02016764 chr4:38805732 TLR1 -0.35 -5.51 -0.44 1.96e-7 Breast cancer; TGCT cis rs459571 0.629 rs441233 chr9:136876021 A/G cg13789015 chr9:136890014 NCRNA00094 -0.32 -5.27 -0.43 5.74e-7 Platelet distribution width; TGCT cis rs727505 0.954 rs67146030 chr7:124561790 T/G cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs7666738 0.830 rs13108422 chr4:99059267 G/A cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.9e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.877 rs10060160 chr5:93387879 G/A cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.97 0.82 6.97e-32 Prudent dietary pattern; TGCT cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg08280861 chr8:58055591 NA 0.4 6.18 0.49 8.45e-9 Developmental language disorder (linguistic errors); TGCT cis rs13242816 1.000 rs12672717 chr7:116128270 G/A cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs9393692 0.905 rs1124999 chr6:26287043 G/T cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.15e-9 Educational attainment; TGCT cis rs8031584 0.651 rs28664821 chr15:31172323 G/A cg08704250 chr15:31115839 NA 0.43 6.21 0.49 7.43e-9 Huntington's disease progression; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg23131131 chr22:24373011 LOC391322 -0.81 -8.78 -0.62 1.11e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9303401 0.659 rs714959 chr17:56628601 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs9457247 0.534 rs1130033 chr6:167385623 C/T cg23791538 chr6:167370224 RNASET2 -0.61 -6.03 -0.48 1.78e-8 Crohn's disease; TGCT cis rs1887596 0.624 rs9319305 chr13:27151048 T/A cg01312412 chr13:27282625 NA 0.27 4.86 0.4 3.51e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs79387448 0.745 rs78136548 chr2:103103740 T/G cg09003973 chr2:102972529 NA 1.13 6.68 0.51 7.38e-10 Gut microbiota (bacterial taxa); TGCT cis rs7172809 0.615 rs907371 chr15:77844375 C/T cg22256960 chr15:77711686 NA 0.48 4.77 0.39 5.1e-6 Glucose homeostasis traits; TGCT cis rs1534166 0.647 rs1464937 chr3:133536655 C/G cg16414030 chr3:133502952 NA 0.42 5.4 0.44 3.27e-7 Alcohol consumption (transferrin glycosylation); TGCT cis rs5769765 0.542 rs761878 chr22:50249677 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.97 6.35 0.5 3.69e-9 Schizophrenia; TGCT cis rs709400 0.567 rs28496120 chr14:103897899 C/T cg26031613 chr14:104095156 KLC1 0.84 9.26 0.64 7.9e-16 Body mass index; TGCT cis rs6840360 0.642 rs11099819 chr4:152430178 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg17264618 chr3:40429014 ENTPD3 0.33 4.76 0.39 5.38e-6 Renal cell carcinoma; TGCT cis rs3749237 0.555 rs2117939 chr3:49415179 C/A cg07636037 chr3:49044803 WDR6 0.64 6.04 0.48 1.63e-8 Resting heart rate; TGCT cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg07617317 chr6:118971624 C6orf204 0.52 5.54 0.45 1.71e-7 Diastolic blood pressure; TGCT cis rs12477438 0.784 rs13407840 chr2:99569928 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs13191362 1.000 rs34637087 chr6:163004064 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3087591 1.000 rs4239229 chr17:29425170 T/G cg24425628 chr17:29625626 OMG;NF1 0.49 7.41 0.55 1.74e-11 Hip circumference; TGCT cis rs2120019 0.935 rs34913788 chr15:75372617 A/C cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs7639513 0.545 rs13061104 chr3:12717321 G/T cg23032965 chr3:12705835 RAF1 0.75 6.87 0.53 2.7e-10 Itch intensity from mosquito bite; TGCT cis rs7914558 0.966 rs943035 chr10:104839152 T/C cg15744005 chr10:104629667 AS3MT -0.39 -4.69 -0.39 7.05e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9611519 0.929 rs926914 chr22:41418154 C/T cg03806693 chr22:41940476 POLR3H -0.69 -6.22 -0.49 6.89e-9 Neuroticism; TGCT cis rs1865760 0.964 rs1324084 chr6:25915134 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.18 0.49 8.59e-9 Height; TGCT cis rs9733 0.596 rs72702552 chr1:150677462 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.49 0.37 1.63e-5 Tonsillectomy; TGCT cis rs35146811 0.735 rs858505 chr7:99819577 G/A cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs10791323 0.569 rs10736608 chr11:133740048 C/T cg15485101 chr11:133734466 NA 0.38 5.56 0.45 1.6e-7 Childhood ear infection; TGCT cis rs7267979 0.844 rs35735333 chr20:25337205 T/G cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3806843 0.676 rs778593 chr5:140027216 T/C cg19875535 chr5:140030758 IK -0.36 -6.34 -0.49 3.84e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6570726 0.738 rs4495284 chr6:145916617 T/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.71e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1348850 0.632 rs11678875 chr2:178509068 A/G cg22681709 chr2:178499509 PDE11A -0.51 -6.34 -0.49 3.93e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7666738 0.830 rs2903154 chr4:99048151 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.657 rs10202292 chr2:238352185 A/T cg14458575 chr2:238380390 NA 0.51 7.51 0.56 1e-11 Prostate cancer; TGCT cis rs921968 0.643 rs497983 chr2:219415189 A/G cg02176678 chr2:219576539 TTLL4 0.38 5.56 0.45 1.58e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs4819052 0.851 rs1999335 chr21:46670613 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.57 0.38 1.15e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs992157 0.764 rs2891077 chr2:219184430 A/C cg00012203 chr2:219082015 ARPC2 0.7 6.59 0.51 1.11e-9 Colorectal cancer; TGCT cis rs453301 0.682 rs2929308 chr8:9084121 T/A cg15556689 chr8:8085844 FLJ10661 -0.7 -6.54 -0.51 1.47e-9 Joint mobility (Beighton score); TGCT cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs9443645 0.869 rs9443626 chr6:79629564 G/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.875 rs9376975 chr6:146355581 T/G cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.659 rs12944971 chr17:56988801 A/T cg25039879 chr17:56429692 SUPT4H1 0.52 4.57 0.38 1.15e-5 Cognitive test performance; TGCT cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.38 0.44 3.51e-7 Menopause (age at onset); TGCT cis rs704 0.790 rs4795433 chr17:26716821 C/T cg10342447 chr17:26645325 TMEM97 -0.51 -4.91 -0.4 2.84e-6 Osteoprotegerin levels; TGCT cis rs1153858 1.000 rs3759899 chr15:45655903 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs1801251 0.896 rs7573208 chr2:233696701 C/A cg25237894 chr2:233734115 C2orf82 -0.27 -4.99 -0.41 2.02e-6 Coronary artery disease; TGCT cis rs71636778 0.509 rs78581866 chr1:27247566 T/C cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg07507251 chr3:52567010 NT5DC2 -0.48 -6.87 -0.53 2.77e-10 Bipolar disorder; TGCT cis rs589448 0.902 rs315113 chr12:69786543 G/T cg14784868 chr12:69753453 YEATS4 -0.87 -10.24 -0.68 3.35e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs72945132 0.882 rs17160039 chr11:70145489 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs6952808 0.792 rs34269264 chr7:1948712 C/T cg04267008 chr7:1944627 MAD1L1 -0.4 -5.44 -0.44 2.71e-7 Bipolar disorder and schizophrenia; TGCT cis rs3749237 1.000 rs11710675 chr3:49751900 C/A cg03060546 chr3:49711283 APEH 0.74 7.53 0.56 9.17e-12 Resting heart rate; TGCT cis rs2066819 1.000 rs117779516 chr12:56750872 G/C cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs7726839 0.578 rs10080150 chr5:593160 C/T cg18765565 chr5:669397 TPPP -0.53 -4.82 -0.4 4.05e-6 Obesity-related traits; TGCT cis rs10751667 0.714 rs7396700 chr11:963863 A/C cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs6671200 0.915 rs259334 chr1:95739701 C/T cg26537280 chr1:95699037 RWDD3 -0.72 -5.18 -0.42 8.67e-7 Stearic acid (18:0) levels; TGCT cis rs8017423 0.967 rs7151776 chr14:90724803 A/G cg04374321 chr14:90722782 PSMC1 0.74 7.45 0.56 1.39e-11 Mortality in heart failure; TGCT cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg04267008 chr7:1944627 MAD1L1 -0.39 -5.22 -0.42 7.29e-7 Bipolar disorder and schizophrenia; TGCT cis rs7249142 0.562 rs12980955 chr19:19283646 T/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.34 -4.62 -0.38 9.65e-6 IgG glycosylation; TGCT cis rs1552244 0.572 rs7645667 chr3:10157337 C/A cg00149659 chr3:10157352 C3orf10 1.15 7.49 0.56 1.12e-11 Alzheimer's disease; TGCT cis rs6840360 0.593 rs4696106 chr4:152606818 A/G cg17479576 chr4:152424074 FAM160A1 -0.62 -6.23 -0.49 6.69e-9 Intelligence (multi-trait analysis); TGCT cis rs2594989 0.831 rs7642605 chr3:11469503 T/C cg00170343 chr3:11313890 ATG7 0.79 5.8 0.46 5.18e-8 Circulating chemerin levels; TGCT cis rs4595586 0.545 rs61939641 chr12:39378001 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2153535 0.580 rs7766852 chr6:8472417 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.29e-6 Motion sickness; TGCT cis rs7020830 0.858 rs67036212 chr9:37133538 A/G cg14294708 chr9:37120828 ZCCHC7 1.29 19.04 0.86 1.29e-38 Schizophrenia; TGCT cis rs1532993 0.518 rs11097570 chr4:98623645 C/T cg05340658 chr4:99064831 C4orf37 -0.38 -4.54 -0.38 1.32e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9616064 0.744 rs9616058 chr22:46974203 G/A cg04500879 chr22:46327243 WNT7B 0.3 4.79 0.4 4.68e-6 Urate levels in obese individuals; TGCT cis rs5750830 0.595 rs4821892 chr22:39795683 G/C cg11247378 chr22:39784982 NA -0.73 -9.43 -0.65 3.04e-16 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.846 rs9376976 chr6:146355605 T/C cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1153858 1.000 rs12591058 chr15:45640172 T/C cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs3092073 0.617 rs8123864 chr20:44598670 T/C cg23252815 chr20:44420276 WFDC3;DNTTIP1 -0.27 -4.44 -0.37 1.93e-5 Intelligence (multi-trait analysis); TGCT cis rs9787249 0.957 rs1046988 chr1:40219065 A/G cg20968010 chr1:40505947 CAP1 0.48 4.63 0.38 9.18e-6 Blood protein levels; TGCT cis rs6671200 1.000 rs34396223 chr1:95697828 C/T cg20701556 chr1:95698924 RWDD3 0.67 5.63 0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs7568458 0.870 rs1058588 chr2:85808871 A/G cg17127132 chr2:85788382 GGCX -0.68 -6.2 -0.49 7.7e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9916302 0.904 rs7210488 chr17:37539819 T/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs12497850 0.931 rs7627404 chr3:48819668 A/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs6714710 0.535 rs13033383 chr2:98339513 C/T cg26665480 chr2:98280029 ACTR1B 0.63 5.82 0.46 4.65e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs9527 1.000 rs9527 chr10:104623578 C/T cg15744005 chr10:104629667 AS3MT -0.52 -6.08 -0.48 1.39e-8 Arsenic metabolism; TGCT cis rs9733 0.526 rs11204698 chr1:150659545 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs7772486 0.754 rs10872580 chr6:146140281 C/T cg23711669 chr6:146136114 FBXO30 -0.9 -10.27 -0.68 2.76e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg21724239 chr8:58056113 NA 0.38 5.15 0.42 1e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg21724239 chr8:58056113 NA 0.39 5.24 0.43 6.73e-7 Developmental language disorder (linguistic errors); TGCT trans rs6089829 0.926 rs7273917 chr20:61665975 G/A cg17470723 chr8:74884337 TCEB1 0.74 6.99 0.53 1.46e-10 Prostate cancer (SNP x SNP interaction); TGCT trans rs561341 1.000 rs8073186 chr17:30244956 T/C cg20587970 chr11:113659929 NA -0.97 -12.13 -0.74 8.27e-23 Hip circumference adjusted for BMI; TGCT cis rs2033711 0.870 rs1465789 chr19:58946056 C/T cg04608855 chr19:58913158 NA 0.56 5.37 0.43 3.69e-7 Uric acid clearance; TGCT cis rs5769765 0.818 rs138850 chr22:50193337 C/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.29 -4.47 -0.37 1.75e-5 Schizophrenia; TGCT cis rs7829975 0.577 rs17684466 chr8:8545233 G/A cg17143192 chr8:8559678 CLDN23 -0.52 -5.21 -0.42 7.57e-7 Mood instability; TGCT cis rs7131987 0.565 rs7968883 chr12:29394191 T/C cg09582351 chr12:29534625 ERGIC2 -0.22 -4.49 -0.37 1.6e-5 QT interval; TGCT trans rs8004664 0.513 rs17126053 chr14:90033633 C/T cg22481606 chr17:56429567 SUPT4H1 -0.66 -6.83 -0.52 3.32e-10 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs114540395 0.858 rs78810836 chr10:103178514 G/A cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs6547741 1.000 rs4666009 chr2:27857992 T/A cg27432699 chr2:27873401 GPN1 0.19 4.71 0.39 6.65e-6 Oral cavity cancer; TGCT cis rs4689388 0.926 rs11732178 chr4:6292643 G/C cg14416269 chr4:6271139 WFS1 0.4 5.29 0.43 5.44e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs11822910 0.815 rs12422015 chr11:57193653 A/G cg00522883 chr11:57194120 SLC43A3 0.35 5.07 0.41 1.43e-6 Platelet distribution width; TGCT cis rs6543140 0.964 rs6543142 chr2:103082006 T/C cg09003973 chr2:102972529 NA 0.55 4.56 0.38 1.2e-5 Blood protein levels; TGCT cis rs931608 0.640 rs2082478 chr19:22539848 G/A cg23859931 chr19:22123797 NA -0.64 -4.8 -0.4 4.43e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs60733400 0.500 rs72644697 chr1:2533605 G/A cg18854424 chr1:2615690 NA 0.44 5.1 0.42 1.22e-6 Multiple sclerosis; TGCT trans rs7618501 1.000 rs7618501 chr3:49772647 A/G cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs6987853 0.931 rs2923431 chr8:42394425 G/C cg20539142 chr8:42623718 CHRNA6 -0.19 -4.55 -0.38 1.26e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs2235642 0.928 rs56289115 chr16:1608934 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.69 -0.46 8.63e-8 Coronary artery disease; TGCT cis rs9911578 0.967 rs1588322 chr17:56990099 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs10479542 0.892 rs7723230 chr5:178980474 T/C cg09060608 chr5:178986726 RUFY1 0.49 5.59 0.45 1.35e-7 Lung cancer; TGCT cis rs9677476 0.515 rs13430145 chr2:231931133 T/C cg27665808 chr2:232055229 NA 0.36 4.6 0.38 1.01e-5 Food antigen IgG levels; TGCT cis rs425277 0.606 rs2460001 chr1:2111030 T/C cg03732007 chr1:2071316 PRKCZ 0.28 6.64 0.51 8.63e-10 Height; TGCT cis rs208520 0.909 rs55813840 chr6:67012508 A/C cg07460842 chr6:66804631 NA 0.69 5.72 0.46 7.53e-8 Exhaled nitric oxide output; TGCT cis rs7829975 0.617 rs4841072 chr8:8791253 C/A cg06636001 chr8:8085503 FLJ10661 -0.72 -6.68 -0.51 7.28e-10 Mood instability; TGCT cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs6430585 0.591 rs12476135 chr2:136486340 T/C cg07169764 chr2:136633963 MCM6 1.12 10.49 0.69 8.04e-19 Corneal structure; TGCT cis rs10927875 0.691 rs2017583 chr1:16350028 A/G cg22431228 chr1:16359049 CLCNKA -0.25 -4.68 -0.39 7.47e-6 Dilated cardiomyopathy; TGCT cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2204008 0.774 rs9669565 chr12:38294428 C/A cg13010199 chr12:38710504 ALG10B 0.57 4.45 0.37 1.89e-5 Bladder cancer; TGCT cis rs986417 1.000 rs1254318 chr14:60902549 T/C cg27398547 chr14:60952738 C14orf39 -1.41 -9.11 -0.63 1.75e-15 Gut microbiota (bacterial taxa); TGCT cis rs546131 0.642 rs512013 chr11:34842225 C/T cg06937548 chr11:34938143 PDHX;APIP 0.54 4.67 0.39 7.64e-6 Lung disease severity in cystic fibrosis; TGCT cis rs9733 0.628 rs11807409 chr1:150683423 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs1982963 1.000 rs3742536 chr14:52507429 C/T cg10843707 chr14:52510701 NID2 0.43 6.63 0.51 9.33e-10 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs933360 0.895 rs4521715 chr7:50769251 G/A cg18232548 chr7:50535776 DDC -0.33 -4.81 -0.4 4.3e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Area under the curve of insulin levels;Insulin levels adjusted for BMI;Ratio of the area under the curve for insulin and the area under the curve for glucose;Incremental insulin; TGCT cis rs853679 0.657 rs1778482 chr6:28240992 G/C cg18815343 chr6:28367644 ZSCAN12 -0.51 -5.14 -0.42 1.02e-6 Depression; TGCT cis rs208520 0.633 rs79679034 chr6:66701724 A/C cg07460842 chr6:66804631 NA 0.9 9.57 0.65 1.41e-16 Exhaled nitric oxide output; TGCT cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg03188948 chr7:1209495 NA 0.41 5.37 0.43 3.66e-7 Longevity;Endometriosis; TGCT cis rs459571 1.000 rs459571 chr9:136912626 C/T cg13789015 chr9:136890014 NCRNA00094 0.4 7.18 0.54 5.63e-11 Platelet distribution width; TGCT cis rs7772486 0.686 rs857877 chr6:145976230 A/C cg13319975 chr6:146136371 FBXO30 0.54 4.98 0.41 2.09e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7909074 1.000 rs10900128 chr10:45393201 G/T cg05187965 chr10:45406764 TMEM72 -0.25 -5.34 -0.43 4.2e-7 Mean corpuscular volume; TGCT cis rs1200821 0.535 rs1208784 chr10:37768433 A/G cg25427524 chr10:38739819 LOC399744 -0.3 -5.39 -0.44 3.43e-7 Hemostatic factors and hematological phenotypes; TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs1014246 0.541 rs887195 chr10:118507976 G/A cg14919929 chr10:118506882 NA -0.37 -5.82 -0.46 4.69e-8 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9486719 0.741 rs2049927 chr6:96848958 C/G cg06623918 chr6:96969491 KIAA0776 -0.84 -6.27 -0.49 5.56e-9 Migraine;Coronary artery disease; TGCT cis rs763121 0.853 rs5750633 chr22:38993467 A/G cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs6988636 1.000 rs28694222 chr8:124195017 C/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs7586879 0.558 rs6718510 chr2:25122323 A/C cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs875971 1.000 rs3981131 chr7:65951677 A/G cg18876405 chr7:65276391 NA 0.35 5.46 0.44 2.48e-7 Aortic root size; TGCT cis rs938554 0.826 rs7376960 chr4:9970570 A/G cg11197905 chr4:10459435 ZNF518B -0.32 -4.44 -0.37 1.97e-5 Blood metabolite levels; TGCT cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg17971929 chr21:40555470 PSMG1 -0.7 -6.62 -0.51 9.53e-10 Cognitive function; TGCT trans rs7618501 0.602 rs2240326 chr3:50128386 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.89 -10.03 -0.67 1.1e-17 Intelligence (multi-trait analysis); TGCT trans rs2915864 0.800 rs78403069 chr5:141514866 T/C cg00220413 chr17:7319074 NLGN2 0.47 6.69 0.51 6.88e-10 Facial morphology (factor 20); TGCT cis rs12135062 0.901 rs2651928 chr1:3101722 C/T cg25382214 chr1:3105252 PRDM16 -0.28 -5.01 -0.41 1.81e-6 Migraine; TGCT cis rs6840360 1.000 rs2007445 chr4:152600370 C/T cg17479576 chr4:152424074 FAM160A1 -0.52 -5.66 -0.45 9.86e-8 Intelligence (multi-trait analysis); TGCT cis rs9322193 0.923 rs1934534 chr6:150033032 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs1371867 0.839 rs1788186 chr8:101335686 T/C cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT trans rs9388451 0.537 rs1739383 chr6:126098915 G/T cg05039488 chr6:79577232 IRAK1BP1 -0.79 -9.13 -0.63 1.57e-15 Brugada syndrome; TGCT cis rs1843834 0.838 rs6436506 chr2:225558242 T/C cg22455342 chr2:225449267 CUL3 0.74 7.25 0.55 3.94e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs17376456 0.569 rs7713956 chr5:93133185 T/C cg21475434 chr5:93447410 FAM172A -0.62 -5.06 -0.41 1.45e-6 Diabetic retinopathy; TGCT cis rs7949030 0.620 rs2428551 chr11:62329758 T/A cg11742103 chr11:62369870 EML3;MTA2 0.6 8.94 0.63 4.65e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8017423 0.935 rs12880102 chr14:90793526 G/T cg04374321 chr14:90722782 PSMC1 -0.74 -7.09 -0.54 8.75e-11 Mortality in heart failure; TGCT cis rs13064411 0.696 rs9860549 chr3:113148368 G/A cg10517650 chr3:113235015 CCDC52 -0.35 -4.69 -0.39 7.18e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs10984561 0.881 rs7032151 chr9:122254047 A/G cg14242995 chr9:122249943 NA 0.72 5.82 0.46 4.75e-8 Pulmonary function decline; TGCT cis rs1008375 0.932 rs964012 chr4:17619184 A/G cg18681998 chr4:17616180 MED28 1.0 10.26 0.68 2.93e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs6089829 0.851 rs6122346 chr20:61661822 C/G cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2836950 0.501 rs4818018 chr21:40694072 C/T cg17971929 chr21:40555470 PSMG1 -0.52 -4.55 -0.38 1.26e-5 Menarche (age at onset); TGCT cis rs10876993 0.893 rs4760168 chr12:58087737 T/G cg15848620 chr12:58087721 OS9 -0.72 -5.86 -0.47 3.82e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7666738 0.830 rs2865981 chr4:99031493 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs17401966 0.931 rs11121545 chr1:10411211 A/G cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs7926906 1.000 rs1540170 chr11:90529456 A/G cg26138821 chr11:89956704 CHORDC1 -0.52 -5.62 -0.45 1.17e-7 Intelligence (multi-trait analysis); TGCT cis rs858239 0.738 rs7807879 chr7:23260588 G/T cg05602783 chr7:23145260 KLHL7 -0.66 -5.18 -0.42 8.78e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs5750830 0.594 rs9611165 chr22:39775250 A/G cg02038168 chr22:39784481 NA -0.64 -5.48 -0.44 2.32e-7 Intelligence (multi-trait analysis); TGCT cis rs10940138 0.830 rs16897180 chr5:67220196 A/C ch.5.1281357F chr5:67228439 NA -0.46 -5.23 -0.42 7.11e-7 Menarche (age at onset); TGCT trans rs3780486 0.846 rs2209948 chr9:33138247 G/A cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT cis rs6840360 0.593 rs7654294 chr4:152690975 T/C cg22705602 chr4:152727874 NA -0.34 -5.91 -0.47 3.06e-8 Intelligence (multi-trait analysis); TGCT cis rs6693567 0.507 rs863862 chr1:150352361 T/A cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7542091 0.704 rs4133950 chr1:210044393 C/G cg23283495 chr1:209979779 IRF6 0.55 5.47 0.44 2.34e-7 Monobrow; TGCT cis rs637571 0.522 rs606978 chr11:65711517 A/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.61 6.22 0.49 7.07e-9 Eosinophil percentage of white cells; TGCT cis rs12950390 0.893 rs4239165 chr17:45847272 A/T cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.6e-6 IgG glycosylation; TGCT cis rs854765 0.663 rs12941550 chr17:17753828 C/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.72 -6.9 -0.53 2.36e-10 Total body bone mineral density; TGCT cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg02187348 chr16:89574699 SPG7 0.59 6.15 0.48 9.78e-9 Multiple myeloma (IgH translocation); TGCT cis rs79387448 0.701 rs11465584 chr2:102982629 G/A cg09003973 chr2:102972529 NA 1.47 10.36 0.68 1.69e-18 Gut microbiota (bacterial taxa); TGCT cis rs10114408 0.959 rs7846905 chr9:96642298 T/C cg13679303 chr9:96623674 NA -0.35 -4.45 -0.37 1.85e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg13393036 chr8:95962371 TP53INP1 -0.58 -7.97 -0.58 8.83e-13 Type 2 diabetes; TGCT cis rs1552244 0.882 rs34706481 chr3:10004123 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.72 -0.52 5.9e-10 Alzheimer's disease; TGCT cis rs6061231 1.000 rs11696991 chr20:60959694 G/T cg24112000 chr20:60950667 NA -0.38 -5.49 -0.44 2.22e-7 Colorectal cancer; TGCT cis rs9457247 1.000 rs444988 chr6:167389674 A/T cg25258033 chr6:167368657 RNASET2 0.2 4.82 0.4 4.03e-6 Crohn's disease; TGCT cis rs7845219 0.525 rs6471501 chr8:95922491 A/G cg13393036 chr8:95962371 TP53INP1 -0.49 -5.49 -0.44 2.2e-7 Type 2 diabetes; TGCT cis rs1008375 0.966 rs6825133 chr4:17577776 C/T cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6700896 0.522 rs6699885 chr1:66159788 C/A cg14976592 chr1:65886160 LEPROT;LEPR -0.54 -4.44 -0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.98 -7.22 -0.54 4.68e-11 Gut microbiome composition (summer); TGCT cis rs9611519 0.590 rs4821980 chr22:41415479 C/G cg03806693 chr22:41940476 POLR3H -0.64 -6.09 -0.48 1.29e-8 Neuroticism; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs17761864 0.762 rs11658881 chr17:2072949 A/G cg02171503 chr17:1588363 PRPF8 -0.49 -4.74 -0.39 5.67e-6 Esophageal cancer (squamous cell); TGCT cis rs7917772 0.536 rs17783771 chr10:104410736 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 7.97 0.58 8.86e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4366490 0.687 rs1939750 chr11:62910271 G/T cg21002970 chr11:62369079 MTA2 0.71 5.03 0.41 1.66e-6 Conotruncal heart defects; TGCT cis rs10782582 0.609 rs1159215 chr1:76317869 A/T cg10523679 chr1:76189770 ACADM -0.5 -4.66 -0.39 7.87e-6 Daytime sleep phenotypes; TGCT cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg17554472 chr22:41940697 POLR3H 0.49 5.07 0.41 1.38e-6 Vitiligo; TGCT cis rs7937682 0.632 rs14133 chr11:111782697 C/G cg09085632 chr11:111637200 PPP2R1B 0.8 7.18 0.54 5.74e-11 Primary sclerosing cholangitis; TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg10263370 chr3:44754102 ZNF502 -0.44 -5.39 -0.44 3.36e-7 Depressive symptoms; TGCT cis rs2354432 0.607 rs7523812 chr1:146673489 A/G cg25205988 chr1:146714368 CHD1L -1.33 -6.35 -0.5 3.68e-9 Mitochondrial DNA levels; TGCT cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg18876405 chr7:65276391 NA 0.37 5.89 0.47 3.33e-8 Aortic root size; TGCT trans rs10506458 0.915 rs79133015 chr12:63396838 G/A cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs7666738 0.830 rs7667796 chr4:99071415 G/T cg18180107 chr4:99064573 C4orf37 -0.57 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs734999 0.588 rs2843402 chr1:2528682 T/C cg18854424 chr1:2615690 NA -0.46 -5.23 -0.43 6.92e-7 Ulcerative colitis; TGCT cis rs11676348 0.846 rs4674257 chr2:218988774 A/G cg00012203 chr2:219082015 ARPC2 -0.52 -4.98 -0.41 2.08e-6 Ulcerative colitis; TGCT cis rs79057730 0.527 rs35316052 chr7:802954 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.66 6.27 0.49 5.39e-9 Initial pursuit acceleration; TGCT cis rs700590 0.692 rs700589 chr5:88108453 T/A cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.24e-7 Educational attainment (years of education); TGCT cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs7772486 0.686 rs4895684 chr6:146114023 A/C cg23711669 chr6:146136114 FBXO30 -0.84 -9.35 -0.64 4.84e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs78487399 0.808 rs6751161 chr2:43752548 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.78 4.84 0.4 3.8e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6671200 0.607 rs7528790 chr1:95709074 A/G cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs7980687 0.596 rs1727319 chr12:123701353 T/C cg00376283 chr12:123451042 ABCB9 0.79 6.8 0.52 3.88e-10 Height;Educational attainment;Head circumference (infant); TGCT cis rs6598955 0.671 rs75517917 chr1:26612926 G/T cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs1580019 0.587 rs7806941 chr7:32553319 G/T cg06627557 chr7:32535165 LSM5;AVL9 1.11 14.04 0.78 2.14e-27 Cognitive ability; TGCT cis rs76455782 1.000 rs58194956 chr4:110131158 A/T cg23196549 chr4:110480700 CCDC109B -0.43 -4.83 -0.4 3.93e-6 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs7909074 0.798 rs10900126 chr10:45386322 G/T cg05187965 chr10:45406764 TMEM72 -0.25 -5.33 -0.43 4.47e-7 Mean corpuscular volume; TGCT cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg07507251 chr3:52567010 NT5DC2 0.46 6.68 0.51 7.37e-10 Bipolar disorder; TGCT cis rs9549367 0.789 rs2287251 chr13:113889499 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.49 -0.44 2.18e-7 Platelet distribution width; TGCT cis rs7772486 0.875 rs2207785 chr6:146332784 T/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.48 -0.37 1.67e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 1.000 rs12207610 chr6:86688016 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs1023500 0.573 rs2269524 chr22:42475703 T/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Schizophrenia; TGCT cis rs7184046 0.797 rs13737 chr15:75932129 G/T cg20655648 chr15:75932815 IMP3 0.61 4.95 0.41 2.33e-6 Height; TGCT cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg13395646 chr4:1353034 KIAA1530 -0.41 -5.03 -0.41 1.7e-6 Longevity; TGCT cis rs651907 0.535 rs35810977 chr3:101531380 G/A cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.58 -0.51 1.19e-9 Colorectal cancer; TGCT cis rs854765 0.583 rs7207395 chr17:17819335 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.91 0.58 1.2e-12 Total body bone mineral density; TGCT cis rs7772486 0.875 rs2814871 chr6:146312274 G/T cg05347473 chr6:146136440 FBXO30 0.52 4.92 0.4 2.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2120019 0.567 rs72625793 chr15:75207083 A/G cg09165964 chr15:75287851 SCAMP5 -0.89 -6.78 -0.52 4.42e-10 Blood trace element (Zn levels); TGCT cis rs2361718 0.603 rs12951255 chr17:78085597 A/G cg09238746 chr17:78121135 EIF4A3 -0.63 -5.71 -0.46 8.05e-8 Yeast infection; TGCT cis rs514406 0.861 rs12038438 chr1:53230581 A/T cg24675658 chr1:53192096 ZYG11B 0.7 8.11 0.59 4.16e-13 Monocyte count; TGCT cis rs8056742 0.643 rs34168095 chr16:85046750 C/G cg00229868 chr16:85520891 NA 0.4 5.09 0.42 1.3e-6 Amyotrophic lateral sclerosis; TGCT cis rs7120118 0.517 rs78310113 chr11:47293553 T/G cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.16e-7 HDL cholesterol; TGCT cis rs6570726 0.935 rs413916 chr6:145831400 T/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.29 -0.43 5.34e-7 Developmental language disorder (linguistic errors); TGCT cis rs2464469 0.631 rs2704218 chr15:58345001 A/T cg12031962 chr15:58353849 ALDH1A2 -0.34 -4.89 -0.4 3.1e-6 Barrett's esophagus or Esophageal adenocarcinoma; TGCT cis rs10501293 0.703 rs4755684 chr11:42988175 C/T cg03447554 chr11:43094025 NA 0.46 6.58 0.51 1.2e-9 Cognitive performance; TGCT cis rs10949834 0.504 rs13238778 chr7:73567709 G/A cg07137043 chr7:73588983 EIF4H -0.74 -5.38 -0.43 3.65e-7 Verbal memory performance (residualized delayed recall change); TGCT cis rs7822232 0.908 rs4977164 chr8:145144912 T/G cg06495924 chr8:145149574 CYC1 -1.04 -4.49 -0.37 1.6e-5 Blood metabolite levels; TGCT cis rs904251 0.861 rs2776877 chr6:37487135 G/A cg08126542 chr6:37504118 NA -0.44 -5.94 -0.47 2.73e-8 Cognitive performance; TGCT cis rs79057730 0.599 rs4720893 chr7:804434 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.76 5.84 0.46 4.31e-8 Initial pursuit acceleration; TGCT cis rs10883723 0.810 rs6584508 chr10:104258567 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs11077998 0.901 rs4789798 chr17:80531643 C/G cg10255544 chr17:80519551 FOXK2 0.23 4.44 0.37 1.96e-5 Reticulocyte fraction of red cells; TGCT cis rs7592578 0.766 rs62181052 chr2:191387858 A/G cg11845111 chr2:191398756 TMEM194B -0.43 -4.63 -0.38 9.26e-6 Diastolic blood pressure; TGCT cis rs7647973 1.000 rs74471041 chr3:49542543 T/G cg06212747 chr3:49208901 KLHDC8B -0.57 -4.56 -0.38 1.21e-5 Menarche (age at onset); TGCT cis rs12477438 0.765 rs56167745 chr2:99600478 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -5.43 -0.44 2.89e-7 Chronic sinus infection; TGCT cis rs826838 1.000 rs12366971 chr12:38737687 T/G cg13010199 chr12:38710504 ALG10B 0.83 6.88 0.53 2.58e-10 Heart rate; TGCT cis rs6684514 1.000 rs12141236 chr1:156302575 A/C cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10256972 0.626 rs62433138 chr7:1050877 T/C cg16145915 chr7:1198662 ZFAND2A -0.47 -5.54 -0.45 1.7e-7 Longevity;Endometriosis; TGCT cis rs1008375 1.000 rs1860596 chr4:17660082 C/T cg16339924 chr4:17578868 LAP3 0.61 5.11 0.42 1.16e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6429082 0.783 rs291364 chr1:235687179 A/G cg26050004 chr1:235667680 B3GALNT2 0.64 5.99 0.47 2.13e-8 Adiposity; TGCT cis rs6754311 0.731 rs309168 chr2:136670298 C/T cg07169764 chr2:136633963 MCM6 0.62 5.75 0.46 6.66e-8 Mosquito bite size; TGCT cis rs8056446 1.000 rs12716853 chr16:78188800 A/G cg00663719 chr16:78231199 WWOX 0.24 4.44 0.37 1.93e-5 Pulmonary function (smoking interaction); TGCT cis rs7681440 0.715 rs17016305 chr4:90791381 A/G cg10208370 chr4:90758469 SNCA -0.54 -5.1 -0.42 1.25e-6 Dementia with Lewy bodies; TGCT cis rs2153535 0.580 rs9406162 chr6:8466196 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4689388 0.926 rs11725500 chr4:6293919 C/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10504229 0.906 rs2270608 chr8:58194688 T/C cg08280861 chr8:58055591 NA 0.35 4.47 0.37 1.72e-5 Developmental language disorder (linguistic errors); TGCT cis rs1153858 1.000 rs12437887 chr15:45669094 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs11931598 0.783 rs28385900 chr4:7050836 C/T cg26116260 chr4:7069785 GRPEL1 0.54 4.8 0.4 4.54e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs66887589 0.616 rs11098498 chr4:120187119 T/C cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.14e-5 Diastolic blood pressure; TGCT cis rs6867032 0.874 rs4975786 chr5:2004724 T/C cg26168224 chr5:2018326 NA -0.38 -6.03 -0.48 1.72e-8 Gut microbiome composition (winter); TGCT cis rs7772486 0.754 rs4895682 chr6:146062861 G/A cg23711669 chr6:146136114 FBXO30 -0.97 -11.02 -0.7 4.06e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs7646881 0.504 rs7617304 chr3:158463101 C/T cg18349298 chr3:158450550 RARRES1 0.41 4.49 0.37 1.64e-5 Tetralogy of Fallot; TGCT cis rs8062405 1.000 rs62037365 chr16:28868962 C/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs524023 1.000 rs537246 chr11:64360630 G/A cg07733098 chr11:64478343 NRXN2 -0.31 -4.67 -0.39 7.7e-6 Urate levels in obese individuals; TGCT cis rs9457247 0.935 rs1794697 chr6:167395410 C/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs10186029 0.680 rs13007271 chr2:213937767 G/C cg08319019 chr2:214017104 IKZF2 0.63 5.81 0.46 5.05e-8 Systemic sclerosis; TGCT cis rs2836974 0.897 rs2776308 chr21:40715175 A/G cg11644478 chr21:40555479 PSMG1 0.87 7.77 0.57 2.59e-12 Cognitive function; TGCT cis rs3733585 0.673 rs10000983 chr4:9951606 T/C cg00071950 chr4:10020882 SLC2A9 -0.55 -6.46 -0.5 2.14e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7192750 0.563 rs12921084 chr16:71880965 T/C cg06353428 chr16:71660113 MARVELD3 0.83 7.37 0.55 2.07e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs6582630 0.502 rs3902522 chr12:38271203 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.33 0.55 2.58e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs9522267 0.535 rs9522304 chr13:112237316 C/T cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs595982 0.546 rs9941490 chr19:49396737 G/A cg15549821 chr19:49342101 PLEKHA4 -0.41 -5.3 -0.43 5.08e-7 Red cell distribution width; TGCT cis rs9372498 0.908 rs72967573 chr6:118696532 C/T cg18833306 chr6:118973337 C6orf204 -0.61 -4.81 -0.4 4.28e-6 Diastolic blood pressure; TGCT cis rs7819412 0.511 rs10108511 chr8:11435516 T/C cg21775007 chr8:11205619 TDH -0.53 -4.97 -0.41 2.16e-6 Triglycerides; TGCT cis rs2153535 0.580 rs2225766 chr6:8481833 G/A cg07606381 chr6:8435919 SLC35B3 0.55 5.17 0.42 9.11e-7 Motion sickness; TGCT cis rs8013055 0.796 rs11628497 chr14:105970789 C/T cg25008857 chr14:105974488 NA 0.27 4.63 0.38 8.92e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg07167872 chr1:205819463 PM20D1 0.57 7.37 0.55 2.12e-11 Menarche (age at onset); TGCT cis rs7552404 0.696 rs12140121 chr1:76455001 A/G cg03433033 chr1:76189801 ACADM 0.73 6.52 0.51 1.61e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12367572 0.965 rs10880696 chr12:45234989 A/G cg04608330 chr12:45269318 NELL2 0.55 5.52 0.44 1.88e-7 Gut microbiome composition (summer); TGCT cis rs6733011 0.578 rs12712038 chr2:99497710 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.68 -0.39 7.53e-6 Bipolar disorder; TGCT trans rs1814175 0.647 rs1404157 chr11:49917301 G/C cg03929089 chr4:120376271 NA -0.59 -6.76 -0.52 4.86e-10 Height; TGCT cis rs1552244 0.554 rs7349576 chr3:10050893 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs9393692 0.620 rs6908402 chr6:26293014 A/T cg05868516 chr6:26286170 HIST1H4H 0.5 4.55 0.38 1.29e-5 Educational attainment; TGCT cis rs7655441 0.964 rs6534702 chr4:80930417 G/T cg02241357 chr4:80885279 ANTXR2 -0.23 -4.45 -0.37 1.92e-5 Neutrophil percentage of white cells; TGCT cis rs7731657 0.537 rs4705907 chr5:130191437 T/A cg08523029 chr5:130500466 HINT1 -0.55 -4.57 -0.38 1.15e-5 Fasting plasma glucose; TGCT cis rs7582180 0.629 rs11693471 chr2:100948062 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.73 0.39 5.96e-6 Intelligence (multi-trait analysis); TGCT cis rs910316 1.000 rs2268617 chr14:75608728 G/A cg11812906 chr14:75593930 NEK9 0.73 7.23 0.54 4.34e-11 Height; TGCT cis rs1538970 0.962 rs2153609 chr1:45814058 A/G cg05343316 chr1:45956843 TESK2 0.66 5.54 0.45 1.74e-7 Platelet count; TGCT cis rs9611565 0.592 rs5758405 chr22:42076381 C/A cg03806693 chr22:41940476 POLR3H 1.06 11.74 0.73 7.15e-22 Vitiligo; TGCT cis rs3008870 0.920 rs3008860 chr1:67391003 G/C cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs2455799 0.613 rs4685258 chr3:15792315 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs11252926 0.598 rs4881256 chr10:453831 T/A cg13477178 chr10:375248 DIP2C -0.25 -4.63 -0.38 9.23e-6 Psychosis in Alzheimer's disease; TGCT trans rs1496653 0.602 rs71322190 chr3:23482493 G/A cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg07341220 chr16:1583899 IFT140;TMEM204 -0.3 -4.7 -0.39 6.89e-6 Coronary artery disease; TGCT cis rs6879260 1.000 rs7730585 chr5:179733440 T/C cg02891314 chr5:179741120 GFPT2 -0.41 -7.16 -0.54 6.21e-11 Height; TGCT cis rs9534288 0.843 rs2094245 chr13:46602207 T/C cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs590121 0.876 rs649257 chr11:75279846 C/T cg26104986 chr11:75275303 SERPINH1 -0.24 -4.55 -0.38 1.25e-5 Coronary artery disease; TGCT cis rs6582630 0.519 rs10880629 chr12:38533611 T/G cg13010199 chr12:38710504 ALG10B 0.62 4.98 0.41 2.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs986417 1.000 rs986417 chr14:60858761 C/T cg27398547 chr14:60952738 C14orf39 -1.25 -8.18 -0.59 2.78e-13 Gut microbiota (bacterial taxa); TGCT cis rs7226408 0.948 rs72883576 chr18:34383714 C/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs6570726 0.791 rs383841 chr6:145888329 G/T cg05347473 chr6:146136440 FBXO30 -0.54 -5.15 -0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2303745 0.589 rs1864116 chr19:17393015 C/T cg04248312 chr19:17393744 ANKLE1 -0.33 -5.55 -0.45 1.62e-7 Systemic lupus erythematosus; TGCT cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.69e-9 Blood metabolite levels; TGCT cis rs11858159 0.525 rs7497832 chr15:24829541 C/G cg08449389 chr15:24672285 NA -0.41 -4.79 -0.4 4.61e-6 Platelet thrombus formation; TGCT cis rs7621025 0.500 rs71630059 chr3:136581611 G/A cg15507776 chr3:136538369 TMEM22 -0.66 -5.68 -0.45 9e-8 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs1497406 0.744 rs12057222 chr1:16508534 A/G cg20430773 chr1:16534157 ARHGEF19 0.54 6.27 0.49 5.36e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8177179 0.666 rs4075352 chr3:133468012 A/G cg08048268 chr3:133502702 NA -0.41 -5.32 -0.43 4.68e-7 Iron status biomarkers (transferrin levels); TGCT cis rs6840360 1.000 rs2278304 chr4:152593409 C/T cg17479576 chr4:152424074 FAM160A1 0.47 4.92 0.4 2.64e-6 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs13019536 chr2:26526978 C/A cg26119090 chr2:26468346 HADHA;HADHB -1.06 -6.98 -0.53 1.57e-10 Gut microbiome composition (summer); TGCT cis rs2836974 0.583 rs9636957 chr21:40705847 G/A cg06238570 chr21:40685208 BRWD1 -0.82 -8.76 -0.62 1.19e-14 Cognitive function; TGCT cis rs7582180 0.629 rs13010911 chr2:100953390 G/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg27535305 chr1:53392650 SCP2 -0.28 -5.42 -0.44 2.98e-7 Monocyte count; TGCT trans rs6089829 0.962 rs3899032 chr20:61658542 G/A cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg18402987 chr7:1209562 NA 0.37 4.52 0.38 1.42e-5 Longevity;Endometriosis; TGCT cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg22963979 chr7:1858916 MAD1L1 -0.44 -7.12 -0.54 7.59e-11 Bipolar disorder and schizophrenia; TGCT cis rs13188771 0.690 rs12521514 chr5:100898219 G/A cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs4478858 0.684 rs2271074 chr1:31734841 C/T cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs7267979 0.718 rs2983489 chr20:25244120 C/A cg16686733 chr20:25566563 NINL 0.51 5.1 0.42 1.22e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg13683864 chr3:40499215 RPL14 1.14 12.22 0.74 4.89e-23 Renal cell carcinoma; TGCT cis rs7666738 0.791 rs4699324 chr4:98967496 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs9473924 0.542 rs2857514 chr6:50811283 C/T cg14470998 chr6:50812995 TFAP2B 1.34 6.82 0.52 3.52e-10 Body mass index; TGCT cis rs801193 1.000 rs6958520 chr7:66151453 T/C cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs1577917 0.874 rs11756621 chr6:86740063 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.86e-7 Response to antipsychotic treatment; TGCT cis rs1018836 0.637 rs6471113 chr8:91519735 A/G cg16814680 chr8:91681699 NA -0.65 -6.42 -0.5 2.58e-9 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs62244186 0.715 rs10212378 chr3:44667286 C/G cg15687855 chr3:44754131 ZNF502 -0.4 -4.77 -0.39 5.01e-6 Depressive symptoms; TGCT cis rs2172802 0.961 rs7690595 chr4:62464414 A/G cg04118610 chr4:62707027 LPHN3 -0.43 -5.1 -0.42 1.21e-6 Partial epilepsies; TGCT cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg22535103 chr8:58192502 C8orf71 -0.43 -5.5 -0.44 2.09e-7 Developmental language disorder (linguistic errors); TGCT cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.69 4.91 0.4 2.75e-6 Platelet count; TGCT cis rs597539 0.652 rs1249474 chr11:68654774 C/T cg06112835 chr11:68658793 MRPL21 0.41 6.7 0.52 6.45e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9311474 0.652 rs352158 chr3:52217704 C/T cg07507251 chr3:52567010 NT5DC2 0.36 4.6 0.38 1.03e-5 Electroencephalogram traits; TGCT cis rs933688 1.000 rs6862125 chr5:90724598 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 8.65 0.61 2.18e-14 Smoking behavior; TGCT cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.78 -0.39 4.85e-6 Obesity-related traits; TGCT cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg02187348 chr16:89574699 SPG7 0.64 7.09 0.54 9.2e-11 Multiple myeloma (IgH translocation); TGCT cis rs7582180 0.663 rs2309794 chr2:100954270 G/A cg14675211 chr2:100938903 LONRF2 0.49 4.89 0.4 3.02e-6 Intelligence (multi-trait analysis); TGCT cis rs5750830 0.621 rs5757665 chr22:39821641 A/G cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs561341 0.700 rs886223 chr17:30229877 G/T cg13647721 chr17:30228624 UTP6 0.6 5.33 0.43 4.5e-7 Hip circumference adjusted for BMI; TGCT cis rs2637266 0.967 rs12254242 chr10:78352934 T/C cg18941641 chr10:78392320 NA 0.42 5.2 0.42 8.09e-7 Pulmonary function; TGCT cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs902774 0.554 rs4503623 chr12:53353759 T/C cg05393297 chr12:53359155 NA -0.74 -8.0 -0.58 7.43e-13 Prostate cancer; TGCT cis rs1552244 0.554 rs34391585 chr3:9999208 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.31 -4.82 -0.4 4.12e-6 Alzheimer's disease; TGCT cis rs637571 0.544 rs12361552 chr11:65701204 G/A cg02427764 chr11:65769310 BANF1;EIF1AD -0.5 -4.82 -0.4 4.04e-6 Eosinophil percentage of white cells; TGCT cis rs56399783 0.901 rs6967664 chr7:2816384 A/G cg19731401 chr7:2775893 GNA12 0.35 4.91 0.4 2.76e-6 Childhood ear infection; TGCT cis rs11809207 0.810 rs17356937 chr1:26504036 G/A cg03844060 chr1:26490628 NA 0.28 5.07 0.41 1.43e-6 Height; TGCT cis rs9467711 0.606 rs9358939 chr6:26416787 C/G cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs875971 0.660 rs10950044 chr7:66042976 A/G cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs9611565 0.649 rs2064189 chr22:42127999 A/G cg06634786 chr22:41940651 POLR3H 0.81 7.59 0.56 6.75e-12 Vitiligo; TGCT cis rs10504229 1.000 rs73591706 chr8:58195633 C/T cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.861 rs551435 chr1:53260537 G/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs10484885 0.878 rs17763820 chr6:90569634 A/G cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs11822910 0.871 rs2581928 chr11:57202790 A/G cg00522883 chr11:57194120 SLC43A3 -0.33 -4.66 -0.39 7.97e-6 Platelet distribution width; TGCT cis rs4689592 0.503 rs11937667 chr4:7057037 C/G cg02503808 chr4:7069936 GRPEL1 -0.9 -7.39 -0.55 1.93e-11 Monocyte percentage of white cells; TGCT cis rs9443645 0.838 rs9350800 chr6:79729489 A/C cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs7258465 0.931 rs11673604 chr19:18540988 T/C cg06462663 chr19:18546047 ISYNA1 0.2 4.7 0.39 6.89e-6 Breast cancer; TGCT cis rs2153535 0.580 rs1115078 chr6:8449638 G/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs4663866 0.908 rs2304670 chr2:239165636 C/T cg17283117 chr2:239148619 HES6 1.0 4.58 0.38 1.1e-5 Irritable bowel syndrome; TGCT cis rs9905704 0.647 rs2108435 chr17:57102133 T/C cg12560992 chr17:57184187 TRIM37 -0.58 -5.33 -0.43 4.39e-7 Testicular germ cell tumor; TGCT cis rs59721556 0.655 rs2364581 chr14:78120752 A/G cg04906283 chr14:77965859 ISM2 0.4 4.5 0.37 1.53e-5 Response to paliperidone in schizophrenia (positive Marder score);Response to paliperidone in schizophrenia (PANSS score);Response to paliperidone in schizophrenia (CGI-S score);Red cell distribution width;Response to paliperidone in schizophrenia (Multivariate); TGCT cis rs7267979 1.000 rs4815405 chr20:25317492 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7714584 1.000 rs2344181 chr5:150262574 T/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs10875595 0.836 rs1363450 chr5:140658363 A/T cg24830062 chr5:140700576 TAF7 0.61 5.2 0.42 8.12e-7 Pulmonary function decline; TGCT cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg07154950 chr22:24370586 NA -0.21 -4.53 -0.38 1.39e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7223966 1.000 rs11079509 chr17:61762148 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.83 0.4 3.93e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs4820539 0.502 rs4820543 chr22:23542535 A/G cg21100191 chr22:23484243 RTDR1 0.74 7.63 0.57 5.45e-12 Bone mineral density; TGCT cis rs7308116 0.935 rs7136201 chr12:108191069 A/G cg19508191 chr12:109124361 CORO1C -0.46 -4.59 -0.38 1.05e-5 Pelvic organ prolapse (moderate/severe); TGCT cis rs2288073 0.965 rs13387930 chr2:24414400 A/G cg02683114 chr2:24398427 C2orf84 -0.25 -5.67 -0.45 9.72e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs6969780 0.630 rs10238095 chr7:27196643 A/G cg04317399 chr7:27170313 HOXA4 -0.45 -4.85 -0.4 3.61e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs1568889 1.000 rs12797155 chr11:28290866 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 7.87 0.58 1.54e-12 Bipolar disorder; TGCT cis rs2997447 0.761 rs17257113 chr1:26449595 G/A cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs2639990 1.000 rs1702831 chr18:72897368 C/A cg03972071 chr18:72917163 ZADH2 0.79 5.47 0.44 2.42e-7 Vascular endothelial growth factor levels; TGCT cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg11301795 chr4:187892539 NA -0.32 -4.81 -0.4 4.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9357506 0.967 rs1891036 chr6:46323630 T/A cg21115430 chr6:46460003 NA -0.24 -4.77 -0.39 5.02e-6 Body mass index; TGCT cis rs3008870 1.000 rs12137403 chr1:67437043 C/T cg08660285 chr1:67390436 MIER1;WDR78 -1.05 -11.32 -0.71 7.78e-21 Lymphocyte percentage of white cells; TGCT cis rs2235642 0.928 rs9932984 chr16:1605051 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.47 -0.44 2.39e-7 Coronary artery disease; TGCT cis rs36051895 0.664 rs884132 chr9:5114522 G/A cg02405213 chr9:5042618 JAK2 -0.69 -9.14 -0.63 1.54e-15 Pediatric autoimmune diseases; TGCT cis rs9291683 0.588 rs12506364 chr4:10023448 C/T cg00071950 chr4:10020882 SLC2A9 0.7 9.52 0.65 1.86e-16 Bone mineral density; TGCT cis rs2956278 0.717 rs2947125 chr12:84687344 G/A cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs4499344 0.556 rs865659 chr19:33139967 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.26 0.6 1.84e-13 Mean platelet volume; TGCT cis rs7666738 0.830 rs3846444 chr4:99032888 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12188164 0.965 rs72717415 chr5:430059 G/A cg21144161 chr5:423903 AHRR 0.26 4.93 0.4 2.59e-6 Cystic fibrosis severity; TGCT cis rs6076065 0.513 rs13037663 chr20:23425812 A/T cg11657817 chr20:23433608 CST11 0.29 4.75 0.39 5.44e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs801193 0.935 rs11772264 chr7:66176387 T/C cg00343986 chr7:65444356 GUSB 0.23 5.13 0.42 1.1e-6 Aortic root size; TGCT cis rs2933343 0.601 rs1680758 chr3:128594897 T/C cg11901034 chr3:128598214 ACAD9 -0.66 -6.11 -0.48 1.2e-8 IgG glycosylation; TGCT cis rs7582180 0.544 rs13026570 chr2:100939498 A/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.94 -0.41 2.43e-6 Intelligence (multi-trait analysis); TGCT cis rs7635838 0.684 rs2606762 chr3:11343889 G/C cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs4950928 0.712 rs7518666 chr1:203163590 C/T cg17014757 chr1:203156097 CHI3L1 -0.38 -4.75 -0.39 5.55e-6 YKL-40 levels; TGCT cis rs9527 0.590 rs11191513 chr10:104772984 T/G cg04362960 chr10:104952993 NT5C2 0.65 5.54 0.45 1.73e-7 Arsenic metabolism; TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg16325326 chr1:53192061 ZYG11B 0.59 6.41 0.5 2.81e-9 Monocyte count; TGCT cis rs11577318 0.853 rs12728971 chr1:26626612 C/T cg12733254 chr1:26682999 NA -0.2 -4.45 -0.37 1.89e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs832540 0.695 rs702686 chr5:56201350 A/G cg12311346 chr5:56204834 C5orf35 -0.59 -6.14 -0.48 1.02e-8 Coronary artery disease; TGCT cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs3806843 0.576 rs246028 chr5:140333513 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg03609598 chr5:56110824 MAP3K1 0.58 4.75 0.39 5.54e-6 Initial pursuit acceleration; TGCT cis rs9788682 1.000 rs7181245 chr15:78814389 C/T cg06917634 chr15:78832804 PSMA4 -0.71 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9790314 0.586 rs1839491 chr3:161126429 C/A cg03342759 chr3:160939853 NMD3 -0.57 -5.94 -0.47 2.64e-8 Morning vs. evening chronotype; TGCT cis rs317689 0.718 rs315122 chr12:69771073 G/T cg20891283 chr12:69753455 YEATS4 0.55 4.62 0.38 9.53e-6 Response to diuretic therapy; TGCT cis rs72615157 0.645 rs76281814 chr7:99846414 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.69 5.32 0.43 4.67e-7 Lung function (FEV1/FVC); TGCT cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.4 0.55 1.78e-11 Schizophrenia; TGCT cis rs12510870 0.599 rs7665972 chr4:74453210 G/A cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.93e-6 Iris color (b* coordinate); TGCT cis rs7424096 0.719 rs3770772 chr2:37192607 T/C cg14987922 chr2:37194071 STRN 0.59 5.15 0.42 9.86e-7 High light scatter reticulocyte percentage of red cells; TGCT cis rs4253772 0.550 rs9615953 chr22:46731024 C/G cg24881330 chr22:46731750 TRMU 0.96 4.79 0.4 4.65e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs36051895 0.664 rs10974960 chr9:5095842 G/A cg02405213 chr9:5042618 JAK2 -0.77 -10.84 -0.7 1.15e-19 Pediatric autoimmune diseases; TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs12780845 0.540 rs3780962 chr10:17193346 A/G cg01003015 chr10:17271136 VIM -0.62 -5.77 -0.46 5.84e-8 Homocysteine levels; TGCT cis rs886126 0.650 rs2339718 chr12:111702646 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.74 0.46 6.99e-8 Coronary heart disease; TGCT cis rs7216064 0.953 rs1599859 chr17:65837193 C/G cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs78487399 0.710 rs72879290 chr2:43633268 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -4.87 -0.4 3.39e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2456568 0.548 rs7113080 chr11:93657520 G/A cg26875233 chr11:93583750 C11orf90 -0.43 -5.36 -0.43 3.96e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs17685 0.712 rs6953342 chr7:75776753 T/C cg19862616 chr7:65841803 NCRNA00174 0.53 9.19 0.64 1.13e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs478304 0.934 rs474483 chr11:65520060 T/G cg27068330 chr11:65405492 SIPA1 0.75 7.57 0.56 7.2e-12 Acne (severe); TGCT cis rs10894604 0.600 rs4486641 chr11:132705848 G/A cg16919708 chr11:133023150 OPCML -0.5 -4.55 -0.38 1.25e-5 Waist-hip ratio; TGCT cis rs908922 0.542 rs4845785 chr1:152510143 C/T cg20991723 chr1:152506922 NA 0.45 6.16 0.48 9.53e-9 Hair morphology; TGCT cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.43 4.64 0.38 8.73e-6 Menopause (age at onset); TGCT cis rs9682041 1.000 rs6773095 chr3:170082181 A/G cg11886554 chr3:170076028 SKIL 0.83 6.42 0.5 2.66e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs877282 0.891 rs12767043 chr10:797943 C/T cg17470449 chr10:769945 NA 0.3 4.72 0.39 6.34e-6 Uric acid levels; TGCT cis rs9486715 1.000 rs9486725 chr6:97061159 C/T cg06623918 chr6:96969491 KIAA0776 -1.12 -15.49 -0.81 8.72e-31 Headache; TGCT cis rs6964587 1.000 rs12536529 chr7:91684086 C/T cg22709100 chr7:91322751 NA -0.28 -4.6 -0.38 1.01e-5 Breast cancer; TGCT cis rs6450176 0.909 rs67199213 chr5:53290648 A/G ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.09e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs909674 0.909 rs1557541 chr22:39851970 C/A cg11247378 chr22:39784982 NA -0.71 -8.43 -0.6 7.29e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9436747 0.615 rs3828038 chr1:66053620 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.7 0.39 6.85e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7267979 0.844 rs6083824 chr20:25363057 G/A cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7044106 0.762 rs1547268 chr9:123408688 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.6 0.51 1.08e-9 Hip circumference adjusted for BMI; TGCT cis rs35160687 0.901 rs11127026 chr2:86531748 C/T cg12542933 chr2:85804724 VAMP8 0.41 4.9 0.4 2.97e-6 Night sleep phenotypes; TGCT cis rs7666738 0.791 rs11730069 chr4:98945772 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs968451 0.789 rs1003644 chr22:39676744 G/A cg17798944 chr22:39715225 SNORD43;RPL3 0.74 7.37 0.55 2.13e-11 Primary biliary cholangitis; TGCT cis rs9435341 0.929 rs1730865 chr1:107605611 A/C cg09367891 chr1:107599246 PRMT6 0.59 4.91 0.4 2.85e-6 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs9388451 0.626 rs3734637 chr6:126081319 G/T cg05901451 chr6:126070800 HEY2 -0.99 -12.54 -0.75 8.6e-24 Brugada syndrome; TGCT cis rs2268241 0.877 rs9975473 chr21:34776441 T/G cg14850771 chr21:34775459 IFNGR2 0.59 4.58 0.38 1.09e-5 Obesity-related traits; TGCT cis rs921968 0.643 rs1850169 chr2:219487299 A/T cg02176678 chr2:219576539 TTLL4 0.37 5.31 0.43 5e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs9457247 0.967 rs2769355 chr6:167380493 G/A cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.08e-6 Crohn's disease; TGCT cis rs9611565 0.525 rs9611548 chr22:41704143 G/T cg13695892 chr22:41940480 POLR3H -0.67 -6.5 -0.5 1.74e-9 Vitiligo; TGCT cis rs4478858 0.684 rs12135540 chr1:31764693 G/A cg07478791 chr1:31886160 SERINC2 -0.48 -4.6 -0.38 1.05e-5 Alcohol dependence; TGCT cis rs9291683 0.609 rs36084205 chr4:10028678 A/C cg11266682 chr4:10021025 SLC2A9 0.66 9.54 0.65 1.61e-16 Bone mineral density; TGCT cis rs8062405 0.964 rs7193733 chr16:28875482 A/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs8103278 0.507 rs4802276 chr19:46260748 T/C cg14061069 chr19:46274453 DMPK 0.6 10.08 0.67 8.3e-18 Coronary artery disease; TGCT cis rs6540559 0.673 rs6540564 chr1:210019910 T/C cg21951975 chr1:209979733 IRF6 0.64 4.82 0.4 4.12e-6 Cleft lip with or without cleft palate; TGCT cis rs8013055 0.796 rs8005568 chr14:105971794 A/G cg25008857 chr14:105974488 NA 0.27 4.52 0.38 1.43e-5 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs1218582 0.741 rs4339857 chr1:154888962 A/G cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs6500602 0.826 rs9932461 chr16:4454170 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 5.61 0.45 1.27e-7 Schizophrenia; TGCT cis rs929354 0.553 rs34498858 chr7:156931337 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs34130287 0.904 rs11775115 chr8:1213744 T/G cg03028061 chr8:218468 NA 0.26 4.45 0.37 1.91e-5 Residual cognition; TGCT cis rs35306767 0.715 rs11253539 chr10:1011347 G/A cg18964960 chr10:1102726 WDR37 0.69 4.82 0.4 4.12e-6 Eosinophil percentage of granulocytes; TGCT cis rs10851411 0.789 rs12913324 chr15:42768379 A/G cg12711755 chr15:41779622 NA -0.18 -4.55 -0.38 1.26e-5 Glucose homeostasis traits; TGCT cis rs7666738 0.830 rs35491210 chr4:99003364 T/C cg17366294 chr4:99064904 C4orf37 0.68 6.96 0.53 1.75e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9616064 0.744 rs9616058 chr22:46974203 G/A cg12346269 chr22:46322472 WNT7B 0.22 4.49 0.37 1.62e-5 Urate levels in obese individuals; TGCT cis rs2067615 0.579 rs11113119 chr12:107200056 C/A cg15890332 chr12:107067104 RFX4 0.28 5.61 0.45 1.27e-7 Heart rate; TGCT cis rs10744422 0.800 rs2343110 chr12:123343571 T/G cg25930673 chr12:123319894 HIP1R -0.88 -5.22 -0.42 7.41e-7 Schizophrenia; TGCT cis rs11785400 1.000 rs6988393 chr8:143740596 A/G cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs6545883 0.868 rs2518932 chr2:61801277 T/A cg15711740 chr2:61764176 XPO1 -0.6 -5.66 -0.45 1e-7 Tuberculosis; TGCT cis rs1801251 0.964 rs13007783 chr2:233566679 G/A cg25237894 chr2:233734115 C2orf82 0.32 5.58 0.45 1.45e-7 Coronary artery disease; TGCT cis rs1552244 0.543 rs28719585 chr3:10050813 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs611744 0.647 rs589347 chr8:109253929 T/A cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs17270561 0.525 rs12201678 chr6:25978993 C/T cg16482183 chr6:26056742 HIST1H1C 1.02 7.76 0.57 2.74e-12 Iron status biomarkers; TGCT cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg10047753 chr17:41438598 NA 0.96 9.49 0.65 2.15e-16 Menopause (age at onset); TGCT cis rs10858047 0.943 rs12034144 chr1:115078549 G/A cg12756093 chr1:115239321 AMPD1 0.46 4.75 0.39 5.61e-6 Autism; TGCT cis rs1215050 0.740 rs783938 chr4:99010336 A/T cg05340658 chr4:99064831 C4orf37 -0.4 -4.77 -0.39 5.09e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.830 rs13138438 chr4:99050545 C/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6558174 0.630 rs6558176 chr8:22522502 C/T cg03733263 chr8:22462867 KIAA1967 -0.52 -4.47 -0.37 1.77e-5 Breast cancer; TGCT cis rs9303401 0.659 rs62081314 chr17:56778328 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg10117171 chr1:25599238 RHD -0.32 -5.22 -0.42 7.32e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs11098499 0.863 rs11098532 chr4:120490726 C/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs3617 0.625 rs2535633 chr3:52859630 C/G cg11645453 chr3:52864694 ITIH4 -0.28 -5.45 -0.44 2.63e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3818285 0.655 rs588160 chr10:111641538 C/T cg00817464 chr10:111662876 XPNPEP1 0.32 5.56 0.45 1.55e-7 Superior crus of antihelix expression; TGCT cis rs7666738 0.716 rs6827474 chr4:99089683 T/G cg17366294 chr4:99064904 C4orf37 0.69 6.76 0.52 4.88e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg18538332 chr22:24372958 LOC391322 -0.84 -9.45 -0.65 2.7e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7020830 0.931 rs13288178 chr9:37107799 A/G cg14294708 chr9:37120828 ZCCHC7 1.29 19.04 0.86 1.29e-38 Schizophrenia; TGCT cis rs17331151 0.573 rs76029595 chr3:52868523 C/T cg07884673 chr3:53033167 SFMBT1 0.49 5.66 0.45 1.01e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2439831 0.867 rs76542740 chr15:43891512 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.93 6.59 0.51 1.14e-9 Lung cancer in ever smokers; TGCT cis rs1046896 0.503 rs2459703 chr17:80690632 C/T cg00960700 chr17:80709150 TBCD -0.5 -5.07 -0.41 1.42e-6 Glycated hemoglobin levels; TGCT cis rs7296418 0.961 rs4275659 chr12:123447928 C/T cg00376283 chr12:123451042 ABCB9 -0.86 -7.9 -0.58 1.27e-12 Platelet count; TGCT cis rs8017423 0.967 rs8022531 chr14:90729931 T/C cg04374321 chr14:90722782 PSMC1 0.78 7.86 0.58 1.59e-12 Mortality in heart failure; TGCT cis rs262150 0.592 rs56062559 chr7:158769109 T/C cg01219135 chr7:158766336 NA -0.51 -5.34 -0.43 4.25e-7 Facial morphology (factor 20); TGCT cis rs4237845 0.537 rs10747787 chr12:58260657 A/G cg23860436 chr12:58378763 NA 0.35 4.77 0.39 5.18e-6 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.765 rs6750876 chr2:99679673 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs526231 0.578 rs6876278 chr5:102249546 A/G cg23492399 chr5:102201601 PAM -0.51 -4.49 -0.37 1.62e-5 Primary biliary cholangitis; TGCT cis rs10875595 0.732 rs62378370 chr5:140679460 T/C cg20560182 chr5:140700478 TAF7 -0.64 -4.78 -0.39 4.77e-6 Pulmonary function decline; TGCT cis rs11992186 0.597 rs11781841 chr8:8595263 T/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.05 -0.41 1.56e-6 Neuroticism; TGCT cis rs3772130 0.923 rs28674947 chr3:121529421 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs1692580 0.807 rs4648627 chr1:2200404 C/T cg21194808 chr1:2205498 SKI 0.29 5.64 0.45 1.08e-7 Coronary artery disease; TGCT trans rs1814175 0.616 rs1794139 chr11:49910855 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs4689388 0.926 rs9998835 chr4:6293237 C/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs797680 0.856 rs7526112 chr1:93747683 T/G cg17826107 chr1:92977322 EVI5 0.23 5.17 0.42 8.96e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg02782426 chr3:40428986 ENTPD3 0.39 4.51 0.38 1.51e-5 Renal cell carcinoma; TGCT cis rs9583531 0.660 rs61971610 chr13:111330476 T/C cg15747390 chr13:111297551 CARS2 0.89 6.16 0.48 9.18e-9 Coronary artery disease; TGCT cis rs5769765 0.773 rs138861 chr22:50202276 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.06 -11.14 -0.71 2.11e-20 Schizophrenia; TGCT cis rs11785400 1.000 rs3735994 chr8:143742683 C/T cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs2847297 1.000 rs6505765 chr18:12782849 C/G cg23544223 chr18:12777786 NA -0.39 -4.55 -0.38 1.26e-5 Rheumatoid arthritis; TGCT cis rs7017914 0.902 rs11991273 chr8:71645860 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs1538970 0.962 rs9429076 chr1:45819489 A/G cg05343316 chr1:45956843 TESK2 0.7 5.63 0.45 1.13e-7 Platelet count; TGCT cis rs1843834 0.755 rs11898692 chr2:225575173 T/C cg22455342 chr2:225449267 CUL3 0.64 6.04 0.48 1.65e-8 IgE levels in asthmatics (D.p. specific); TGCT cis rs6089829 0.925 rs6122086 chr20:61664528 T/C cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs1635 0.655 rs16893929 chr6:28270817 C/T cg15743358 chr6:28303923 ZNF323 -1.34 -5.96 -0.47 2.44e-8 Schizophrenia; TGCT cis rs13191362 1.000 rs71567659 chr6:163001736 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6500602 0.702 rs2270366 chr16:4558615 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.31 -5.67 -0.45 9.57e-8 Schizophrenia; TGCT cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg17328964 chr8:145687451 CYHR1 0.48 6.95 0.53 1.84e-10 Age at first birth; TGCT cis rs950169 0.881 rs62029599 chr15:84956565 A/C cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs6909279 0.678 rs9479056 chr6:151848899 C/A cg14416726 chr6:151773293 C6orf211;RMND1 0.64 5.79 0.46 5.32e-8 Bone mineral density; TGCT cis rs28595532 0.920 rs115838006 chr4:119754356 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7216064 1.000 rs8071463 chr17:65938655 C/T cg12091567 chr17:66097778 LOC651250 0.86 6.36 0.5 3.47e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2201728 0.967 rs13117371 chr4:100222067 C/T cg07219303 chr4:100140905 ADH6 -0.35 -5.14 -0.42 1.04e-6 Cardiac Troponin-T levels; TGCT cis rs743757 1.000 rs734767 chr3:50431410 C/G cg27186011 chr3:49840712 C3orf54 0.73 4.73 0.39 5.97e-6 Diastolic blood pressure; TGCT cis rs7044106 0.791 rs3904196 chr9:123480369 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.85 0.4 3.57e-6 Hip circumference adjusted for BMI; TGCT cis rs9534288 0.797 rs718530 chr13:46563653 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs6951245 0.744 rs10265758 chr7:1172518 C/T cg03188948 chr7:1209495 NA 0.58 5.61 0.45 1.27e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs739496 0.843 rs650887 chr12:112008242 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.59 0.45 1.4e-7 Platelet count; TGCT cis rs10782582 0.609 rs5745430 chr1:76332994 C/T cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs7949030 0.626 rs11231144 chr11:62328038 A/G cg22862634 chr11:62369728 EML3;MTA2 0.73 9.21 0.64 9.99e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9372498 0.536 rs28605789 chr6:118889952 G/A cg07617317 chr6:118971624 C6orf204 0.5 5.32 0.43 4.71e-7 Diastolic blood pressure; TGCT cis rs9790314 0.902 rs9863590 chr3:161116445 T/C cg03342759 chr3:160939853 NMD3 -0.44 -4.53 -0.38 1.34e-5 Morning vs. evening chronotype; TGCT cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs75686122 0.892 rs17807832 chr8:104633966 G/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7940866 0.874 rs7111478 chr11:130819628 A/G cg12179176 chr11:130786555 SNX19 0.55 5.42 0.44 3.03e-7 Schizophrenia; TGCT cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg07424592 chr7:64974309 NA -1.27 -7.28 -0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs1475911 0.671 rs12483409 chr21:43521902 G/A cg19766460 chr21:43528205 UMODL1;C21orf128 0.64 9.26 0.64 7.72e-16 IgG glycosylation; TGCT cis rs9910055 0.529 rs228749 chr17:42174570 A/G cg13607699 chr17:42295918 UBTF -0.63 -5.13 -0.42 1.11e-6 Total body bone mineral density; TGCT cis rs9486719 1.000 rs12529248 chr6:96895377 T/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs9486715 0.867 rs3849199 chr6:97049191 T/C cg06623918 chr6:96969491 KIAA0776 -1.11 -15.34 -0.81 1.96e-30 Headache; TGCT cis rs8077889 0.619 rs1230399 chr17:41845403 C/T cg26893861 chr17:41843967 DUSP3 -1.16 -21.87 -0.89 2.22e-44 Triglycerides; TGCT cis rs7959452 0.640 rs12370042 chr12:69692420 C/G cg11871910 chr12:69753446 YEATS4 0.63 6.37 0.5 3.34e-9 Blood protein levels; TGCT cis rs11679640 0.543 rs4487134 chr2:43107129 G/T cg00484711 chr2:42331922 NA -0.2 -4.59 -0.38 1.06e-5 White matter hyperintensity burden; TGCT cis rs736408 1.000 rs2710331 chr3:52837855 T/C cg07507251 chr3:52567010 NT5DC2 0.49 6.55 0.51 1.41e-9 Bipolar disorder; TGCT cis rs514406 0.861 rs7524476 chr1:53240212 C/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs587847 0.558 rs624991 chr15:37658208 T/G cg16890051 chr15:37175029 LOC145845 -0.37 -4.44 -0.37 1.95e-5 Intraocular pressure; TGCT cis rs7208859 0.673 rs9889968 chr17:29220128 C/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2580764 0.566 rs2968794 chr2:55290651 C/G cg09592903 chr2:55203963 RTN4 -0.25 -5.65 -0.45 1.04e-7 Mean platelet volume; TGCT cis rs858239 0.669 rs6461687 chr7:23116580 A/G cg05407003 chr7:23246146 NA -0.31 -5.05 -0.41 1.54e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg22920501 chr2:26401640 FAM59B 0.83 5.42 0.44 3.04e-7 Gut microbiome composition (summer); TGCT cis rs4654899 0.758 rs6658679 chr1:21376451 T/C cg01072550 chr1:21505969 NA -0.57 -9.39 -0.64 3.77e-16 Superior frontal gyrus grey matter volume; TGCT cis rs2180341 0.960 rs7756884 chr6:127684018 A/G cg24812749 chr6:127587940 RNF146 1.01 7.62 0.56 5.59e-12 Breast cancer; TGCT cis rs644799 1.000 rs563653 chr11:95561488 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7523050 0.643 rs35860016 chr1:109404639 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs6845621 0.754 rs9992560 chr4:18881056 G/A cg12196642 chr4:18937545 NA -0.24 -4.49 -0.37 1.62e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs2797160 1.000 rs1630556 chr6:126013155 A/G cg05901451 chr6:126070800 HEY2 0.74 6.12 0.48 1.15e-8 Endometrial cancer; TGCT cis rs2281845 0.965 rs7516023 chr1:201085521 C/T cg22815214 chr1:201083145 CACNA1S 0.26 4.67 0.39 7.77e-6 Permanent tooth development; TGCT cis rs921968 0.541 rs3770216 chr2:219443717 A/G cg02176678 chr2:219576539 TTLL4 -0.49 -6.93 -0.53 1.99e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs12681288 0.862 rs2600487 chr8:1016903 C/T cg08872321 chr8:1308229 NA -0.26 -4.68 -0.39 7.47e-6 Schizophrenia; TGCT cis rs2677744 0.626 rs11207 chr15:91497239 C/T cg01710897 chr15:91497902 RCCD1 0.33 4.52 0.38 1.41e-5 Attention deficit hyperactivity disorder; TGCT cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg05177932 chr16:89631655 NA 0.29 4.89 0.4 3.12e-6 Vitiligo; TGCT cis rs13223928 0.592 rs4722439 chr7:3155858 C/T cg19214707 chr7:3157722 NA 0.46 6.97 0.53 1.7e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs9534288 0.797 rs7995256 chr13:46579414 A/T cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs79149102 0.579 rs8039433 chr15:75367367 T/C cg09165964 chr15:75287851 SCAMP5 -1.03 -5.67 -0.45 9.4e-8 Lung cancer; TGCT cis rs798766 1.000 rs3099555 chr4:1725651 T/C cg05874882 chr4:1763078 NA -0.34 -4.49 -0.37 1.62e-5 Bladder cancer;Urinary bladder cancer; TGCT cis rs2239547 0.603 rs4687698 chr3:53097108 C/T cg11645453 chr3:52864694 ITIH4 0.31 4.99 0.41 1.98e-6 Schizophrenia; TGCT cis rs6570726 0.791 rs1280275 chr6:145892402 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.772 rs10908445 chr1:154849590 A/G cg03351412 chr1:154909251 PMVK -0.46 -4.46 -0.37 1.82e-5 Prostate cancer; TGCT cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs6964587 0.967 rs28615927 chr7:91600648 C/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs155076 1.000 rs261427 chr13:21860998 G/A cg14456004 chr13:21872349 NA -1.23 -9.97 -0.67 1.49e-17 White matter hyperintensity burden; TGCT cis rs174601 0.861 rs174547 chr11:61570783 C/T cg01500311 chr11:61656094 FADS3 0.3 5.09 0.42 1.31e-6 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs174479 0.677 rs1000778 chr11:61655305 A/G cg01500311 chr11:61656094 FADS3 0.29 5.16 0.42 9.71e-7 Sphingolipid levels; TGCT cis rs7255045 0.752 rs2242512 chr19:12975599 G/A cg23899408 chr19:12877188 HOOK2 -0.61 -4.99 -0.41 1.97e-6 Mean corpuscular volume; TGCT cis rs59197085 0.636 rs62479609 chr7:128443492 C/G cg00260937 chr7:128520193 KCP 0.47 4.86 0.4 3.49e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs2692947 0.673 rs2917662 chr2:96794957 G/A cg22654517 chr2:96458247 NA 0.22 4.58 0.38 1.11e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6921919 0.583 rs6907950 chr6:28370246 C/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs916888 0.773 rs199457 chr17:44795469 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.63 -5.4 -0.44 3.3e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs644799 0.965 rs2508713 chr11:95547927 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11096990 0.634 rs2381371 chr4:39273034 A/G cg20847110 chr4:39482781 LOC401127 0.16 4.55 0.38 1.26e-5 Cognitive function; TGCT cis rs826838 0.616 rs2200605 chr12:38624088 G/A cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Heart rate; TGCT trans rs10435719 0.744 rs11250175 chr8:11792758 G/T cg15556689 chr8:8085844 FLJ10661 0.77 7.37 0.55 2.13e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs10927875 1.000 rs3979179 chr1:16306846 A/G cg21385522 chr1:16154831 NA 0.76 8.44 0.6 7.12e-14 Dilated cardiomyopathy; TGCT cis rs8177253 1.000 rs8177240 chr3:133477701 T/G cg08048268 chr3:133502702 NA -0.65 -9.71 -0.66 6.45e-17 Iron status biomarkers; TGCT cis rs2204008 0.811 rs8189445 chr12:38276295 T/C cg13010199 chr12:38710504 ALG10B 0.61 4.67 0.39 7.69e-6 Bladder cancer; TGCT cis rs9972944 0.756 rs9899781 chr17:63769384 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs17376456 0.542 rs17083380 chr5:93170476 C/G cg25358565 chr5:93447407 FAM172A -0.6 -5.69 -0.45 8.75e-8 Diabetic retinopathy; TGCT cis rs7937682 0.883 rs1789351 chr11:111456436 T/A cg09085632 chr11:111637200 PPP2R1B -0.97 -9.75 -0.66 5.24e-17 Primary sclerosing cholangitis; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.48 -4.48 -0.37 1.69e-5 Prudent dietary pattern; TGCT cis rs11696501 0.688 rs1013562 chr20:44310744 A/G cg11783356 chr20:44313418 WFDC10B -0.33 -4.57 -0.38 1.18e-5 Brain structure; TGCT cis rs4820539 0.902 rs9612237 chr22:23472954 T/C cg21100191 chr22:23484243 RTDR1 0.89 10.51 0.69 7.38e-19 Bone mineral density; TGCT cis rs9814567 0.762 rs13067564 chr3:134209956 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.83 6.53 0.51 1.51e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2742417 0.967 rs9311378 chr3:45763135 C/T cg04837898 chr3:45731254 SACM1L -0.51 -5.27 -0.43 5.85e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6912958 0.781 rs9444522 chr6:88309705 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -5.2 -0.42 7.9e-7 Monocyte percentage of white cells; TGCT cis rs11249608 0.548 rs6860309 chr5:178451428 T/C cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs7635838 0.785 rs7427412 chr3:11535020 G/A cg00170343 chr3:11313890 ATG7 0.68 6.36 0.5 3.46e-9 HDL cholesterol; TGCT cis rs7666738 0.830 rs13102369 chr4:99045912 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7264396 0.673 rs2425163 chr20:34432670 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.83 -0.4 3.89e-6 Total cholesterol levels; TGCT cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg17747265 chr1:1875780 NA -0.38 -7.18 -0.54 5.67e-11 Body mass index; TGCT cis rs853679 0.517 rs9393885 chr6:28050009 A/T cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs36051895 0.659 rs16922576 chr9:5064193 T/C cg02405213 chr9:5042618 JAK2 -0.69 -8.63 -0.61 2.43e-14 Pediatric autoimmune diseases; TGCT trans rs12339966 0.653 rs1489174 chr9:11284628 T/G cg07173112 chr1:1114698 TTLL10 -0.34 -6.84 -0.52 3.15e-10 Systolic blood pressure; TGCT cis rs2708240 0.666 rs2710121 chr7:147608448 C/T cg02373104 chr7:147601429 MIR548F3;CNTNAP2 -0.17 -4.45 -0.37 1.9e-5 QT interval (drug interaction); TGCT cis rs6815814 0.904 rs73236628 chr4:38825443 C/T cg02016764 chr4:38805732 TLR1 -0.3 -4.62 -0.38 9.47e-6 Breast cancer; TGCT cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs11627546 0.615 rs75507160 chr14:70366060 A/T cg10496350 chr14:71275911 MAP3K9 -0.94 -4.44 -0.37 1.96e-5 Red blood cell traits; TGCT cis rs28374715 0.532 rs28463309 chr15:41666716 A/G cg18705301 chr15:41695430 NDUFAF1 -0.89 -14.75 -0.8 4.62e-29 Ulcerative colitis; TGCT cis rs933688 1.000 rs11950530 chr5:90688740 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.91e-14 Smoking behavior; TGCT cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.13 0.63 1.6e-15 Cognitive function; TGCT cis rs10186029 0.680 rs11689451 chr2:213937840 C/T cg08319019 chr2:214017104 IKZF2 0.63 5.81 0.46 5.05e-8 Systemic sclerosis; TGCT cis rs986417 1.000 rs8004736 chr14:61053061 T/C cg27398547 chr14:60952738 C14orf39 1.57 8.46 0.6 6.32e-14 Gut microbiota (bacterial taxa); TGCT cis rs732765 0.734 rs7152804 chr14:75164008 T/C cg06637938 chr14:75390232 RPS6KL1 -0.58 -5.03 -0.41 1.67e-6 Non-small cell lung cancer; TGCT cis rs4665809 1.000 rs4665820 chr2:26309150 T/C cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs7973719 1.000 rs1839622 chr12:7334534 G/C cg07052231 chr12:7363540 PEX5 0.35 5.17 0.42 9.04e-7 IgG glycosylation; TGCT cis rs28595532 0.920 rs116514715 chr4:119756280 G/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs6582630 0.537 rs7299661 chr12:38527713 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.37e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9311474 1.000 rs6445358 chr3:52308845 C/G cg07507251 chr3:52567010 NT5DC2 0.43 6.02 0.48 1.81e-8 Electroencephalogram traits; TGCT cis rs6831352 0.918 rs34936974 chr4:100052384 A/G cg12011299 chr4:100065546 ADH4 0.42 4.98 0.41 2.06e-6 Alcohol dependence; TGCT cis rs2455799 0.613 rs3856830 chr3:15806520 A/C cg16303742 chr3:15540471 COLQ -0.25 -4.8 -0.4 4.53e-6 Mean platelet volume; TGCT cis rs736408 0.677 rs678 chr3:52820981 A/T cg10802521 chr3:52805072 NEK4 -0.73 -8.77 -0.62 1.13e-14 Bipolar disorder; TGCT cis rs9911578 0.835 rs9904993 chr17:56468569 G/T cg12560992 chr17:57184187 TRIM37 -0.72 -7.97 -0.58 8.62e-13 Intelligence (multi-trait analysis); TGCT cis rs9400467 0.537 rs12210707 chr6:111538387 C/T cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs28595532 0.920 rs56342843 chr4:119765070 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2932538 0.961 rs1238 chr1:113214097 G/A cg22162597 chr1:113214053 CAPZA1 -0.28 -6.31 -0.49 4.46e-9 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs801193 0.844 rs732465 chr7:65998450 T/C cg00343986 chr7:65444356 GUSB 0.2 4.51 0.38 1.51e-5 Aortic root size; TGCT trans rs1814175 0.616 rs847641 chr11:49919261 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs35883536 0.565 rs2647322 chr1:101031962 G/T cg10298815 chr1:101004474 GPR88 0.25 4.69 0.39 7.06e-6 Monocyte count; TGCT cis rs7772486 0.658 rs6570706 chr6:145962922 T/C cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg12311346 chr5:56204834 C5orf35 -0.63 -6.36 -0.5 3.5e-9 Initial pursuit acceleration; TGCT cis rs2204008 0.777 rs2049130 chr12:38444837 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.46 0.56 1.32e-11 Bladder cancer; TGCT cis rs2458413 0.933 rs2669450 chr8:105371752 C/T cg13045555 chr8:105342365 NA 0.42 6.92 0.53 2.11e-10 Paget's disease; TGCT cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg05754148 chr16:3507555 NAT15 -0.44 -5.35 -0.43 4.09e-7 Tuberculosis; TGCT cis rs595982 0.702 rs626974 chr19:49375900 T/C cg21252483 chr19:49399788 TULP2 -0.27 -4.81 -0.4 4.37e-6 Red cell distribution width; TGCT cis rs8063160 0.778 rs11076649 chr16:90059336 C/G cg12064134 chr16:90016061 DEF8 -0.52 -4.44 -0.37 2e-5 Red vs non-red hair color;Light vs. dark hair color;Brown vs. non-brown hair color; TGCT cis rs10992471 0.756 rs2761681 chr9:95186937 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.31 -0.49 4.46e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7267979 0.933 rs2387887 chr20:25427081 G/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs908922 0.702 rs569232 chr1:152526643 A/G cg20991723 chr1:152506922 NA 0.41 5.47 0.44 2.43e-7 Hair morphology; TGCT cis rs763121 0.853 rs10135 chr22:39082174 C/T cg06022373 chr22:39101656 GTPBP1 -0.74 -7.88 -0.58 1.43e-12 Menopause (age at onset); TGCT cis rs7833790 0.963 rs2400473 chr8:82703403 C/T cg06027949 chr8:82754900 SNX16 -0.73 -4.66 -0.39 8.1e-6 Diastolic blood pressure; TGCT cis rs6882076 1.000 rs9715911 chr5:156394441 G/A cg12943317 chr5:156479607 HAVCR1 -0.31 -6.09 -0.48 1.31e-8 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs9435341 0.826 rs1730858 chr1:107619244 T/C cg09367891 chr1:107599246 PRMT6 -0.62 -5.29 -0.43 5.29e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs7220711 1.000 rs8072333 chr17:41793893 C/T cg26893861 chr17:41843967 DUSP3 0.5 4.49 0.37 1.61e-5 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs12497850 1.000 rs4858831 chr3:48735558 C/T cg07636037 chr3:49044803 WDR6 0.91 10.29 0.68 2.43e-18 Parkinson's disease; TGCT cis rs826838 0.804 rs6580755 chr12:39159190 C/T cg26384229 chr12:38710491 ALG10B 1.06 10.03 0.67 1.05e-17 Heart rate; TGCT cis rs7586879 0.789 rs13428763 chr2:25132855 T/G cg01884057 chr2:25150051 NA 0.27 4.82 0.4 4.16e-6 Body mass index; TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.55 -4.92 -0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs3733631 1.000 rs28688000 chr4:104620713 A/G cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT cis rs9527 0.590 rs10883836 chr10:104891198 T/C cg15744005 chr10:104629667 AS3MT -0.43 -4.94 -0.41 2.45e-6 Arsenic metabolism; TGCT cis rs4144743 1.000 rs7223003 chr17:45324293 G/A cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs868036 0.681 rs4548812 chr15:68060552 G/A cg05925327 chr15:68127851 NA -0.51 -4.97 -0.41 2.21e-6 Restless legs syndrome; TGCT cis rs13217239 0.621 rs12527231 chr6:27001288 G/A cg26531700 chr6:26746687 NA 0.68 6.86 0.52 2.83e-10 Schizophrenia; TGCT cis rs13191362 1.000 rs13206253 chr6:163166902 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.68 5.79 0.46 5.5e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg21951975 chr1:209979733 IRF6 0.7 6.01 0.47 1.92e-8 Cleft lip with or without cleft palate; TGCT cis rs899997 1.000 rs11072794 chr15:79006582 A/G cg04896959 chr15:78267971 NA 0.36 5.53 0.44 1.81e-7 Coronary artery disease or large artery stroke; TGCT cis rs4713118 0.628 rs12179134 chr6:27675469 A/G cg27179866 chr6:27740120 NA 0.41 4.5 0.37 1.53e-5 Parkinson's disease; TGCT cis rs6978712 1.000 rs80308641 chr7:127147638 C/A cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs13242816 1.000 rs3801994 chr7:116190469 G/A cg02799643 chr7:116139180 CAV2 -0.45 -5.55 -0.45 1.66e-7 P wave duration; TGCT trans rs114540395 0.858 rs17767748 chr10:103285900 A/G cg25791773 chr11:129910324 NA -0.76 -6.72 -0.52 5.95e-10 Schizophrenia; TGCT cis rs58688157 0.960 rs11246213 chr11:612967 A/G cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs2070433 0.539 rs1008549 chr21:47959698 C/T cg12379764 chr21:47803548 PCNT 0.53 5.46 0.44 2.51e-7 Lymphocyte counts; TGCT cis rs35306767 0.761 rs12773961 chr10:1013215 C/G cg20503657 chr10:835505 NA 0.57 6.34 0.49 3.86e-9 Eosinophil percentage of granulocytes; TGCT cis rs853679 0.546 rs200996 chr6:27811828 G/A cg10876282 chr6:28092338 ZSCAN16 0.74 4.44 0.37 1.98e-5 Depression; TGCT cis rs116095464 0.510 rs60844864 chr5:267000 A/G cg22857025 chr5:266934 NA -0.34 -6.59 -0.51 1.1e-9 Breast cancer; TGCT cis rs7312933 0.558 rs3747560 chr12:42719890 A/G cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.3e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10782582 0.569 rs2131557 chr1:76388589 A/C cg03433033 chr1:76189801 ACADM 0.46 4.54 0.38 1.32e-5 Daytime sleep phenotypes; TGCT cis rs6570726 0.755 rs2092297 chr6:145893765 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.861 rs503296 chr1:53283088 A/G cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs892961 0.899 rs747482 chr17:75412109 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.82 0.52 3.51e-10 Airflow obstruction; TGCT cis rs4727027 0.635 rs12111923 chr7:148885877 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.58 5.05 0.41 1.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9911578 0.785 rs10853008 chr17:56993407 T/C cg05425664 chr17:57184151 TRIM37 0.6 4.97 0.41 2.18e-6 Intelligence (multi-trait analysis); TGCT cis rs769267 0.930 rs1063966 chr19:19616742 G/A cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT trans rs561341 0.609 rs9906443 chr17:30185565 C/T cg20587970 chr11:113659929 NA 0.66 7.7 0.57 3.76e-12 Hip circumference adjusted for BMI; TGCT cis rs7072216 0.763 rs7910014 chr10:100172110 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs3774830 0.685 rs73212741 chr4:5464450 G/C cg26943120 chr4:5472116 STK32B 0.21 4.71 0.39 6.48e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs3096299 0.967 rs2911255 chr16:89487137 C/T cg06640241 chr16:89574553 SPG7 0.64 6.33 0.49 4.18e-9 Multiple myeloma (IgH translocation); TGCT cis rs6570726 0.935 rs408723 chr6:145838535 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7178572 1.000 rs6495240 chr15:77766556 T/C cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs1218582 0.710 rs9793588 chr1:154878878 C/G cg03351412 chr1:154909251 PMVK 0.54 5.02 0.41 1.72e-6 Prostate cancer; TGCT cis rs7666738 0.830 rs6840766 chr4:99016260 C/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1018836 0.923 rs13277387 chr8:91633713 C/G cg16814680 chr8:91681699 NA -0.84 -8.98 -0.63 3.58e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs16957091 0.607 rs28633493 chr15:43263307 T/C cg17935677 chr15:44119062 WDR76 0.53 4.72 0.39 6.35e-6 MGMT methylation in smokers; TGCT cis rs7312933 0.670 rs10880258 chr12:42547531 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10484885 0.680 rs72921943 chr6:90581542 A/C cg13799429 chr6:90582589 CASP8AP2 -0.55 -6.49 -0.5 1.87e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg13866156 chr1:1669148 SLC35E2 0.2 4.45 0.37 1.89e-5 Body mass index; TGCT cis rs6693567 0.565 rs1694379 chr1:150292417 C/A cg09579323 chr1:150459698 TARS2 0.54 4.84 0.4 3.86e-6 Migraine; TGCT cis rs892961 0.965 rs2411111 chr17:75402540 A/T cg05865280 chr17:75406074 SEPT9 0.3 7.18 0.54 5.59e-11 Airflow obstruction; TGCT cis rs7267979 0.706 rs6037069 chr20:25234166 C/T cg03522245 chr20:25566470 NINL 0.58 6.22 0.49 6.92e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs346785 0.692 rs6501883 chr17:74289908 A/G cg09812376 chr17:74270190 QRICH2 -0.36 -5.33 -0.43 4.43e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs1045714 0.887 rs73033694 chr7:2637139 G/A cg17215154 chr7:2644645 IQCE 0.29 5.12 0.42 1.12e-6 Urate levels in lean individuals; TGCT cis rs6586111 1.000 rs7071690 chr10:82376017 C/T cg03086067 chr10:82368399 SH2D4B -0.23 -4.54 -0.38 1.33e-5 Capecitabine sensitivity; TGCT cis rs9611519 0.828 rs4822008 chr22:41539206 C/G cg13695892 chr22:41940480 POLR3H -0.51 -4.58 -0.38 1.1e-5 Neuroticism; TGCT cis rs12971120 0.891 rs3764510 chr18:72166846 A/G cg26446133 chr18:72167187 CNDP2 -0.36 -6.11 -0.48 1.2e-8 Refractive error; TGCT cis rs600231 0.577 rs35826299 chr11:65240964 T/C cg17120908 chr11:65337727 SSSCA1 -0.57 -4.45 -0.37 1.9e-5 Bone mineral density; TGCT cis rs1775715 0.707 rs2799019 chr10:32142850 C/T cg14930904 chr10:32216787 ARHGAP12 0.55 5.41 0.44 3.12e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs11690935 0.921 rs6710698 chr2:172596078 G/C cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.34 -0.74 2.55e-23 Schizophrenia; TGCT cis rs7666738 0.830 rs17483521 chr4:98974058 A/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7914558 1.000 rs7077291 chr10:104945751 C/T cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.65e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.09 -0.42 1.32e-6 Initial pursuit acceleration; TGCT cis rs6840360 0.615 rs12647586 chr4:152607568 G/C cg22705602 chr4:152727874 NA -0.32 -5.43 -0.44 2.85e-7 Intelligence (multi-trait analysis); TGCT cis rs10465746 0.967 rs12732697 chr1:84349283 A/G cg10977910 chr1:84465055 TTLL7 0.64 6.27 0.49 5.53e-9 Obesity-related traits; TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg08859206 chr1:53392774 SCP2 0.41 6.31 0.49 4.48e-9 Monocyte count; TGCT cis rs7666738 0.830 rs62321587 chr4:98997958 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs1178127 0.694 rs1178136 chr7:18772264 A/G cg04900931 chr7:6644352 C7orf26 0.21 6.73 0.52 5.66e-10 Facial morphology (factor 12, vertical position of sublabial sulcus relative to central midface); TGCT cis rs9611565 0.729 rs169362 chr22:41827589 G/C cg03806693 chr22:41940476 POLR3H 1.03 11.32 0.71 7.58e-21 Vitiligo; TGCT cis rs61990749 0.597 rs72685264 chr14:78152998 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.69 -0.39 7.04e-6 Fibroblast growth factor basic levels; TGCT cis rs2562456 0.917 rs2681389 chr19:21692575 G/A cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs2688608 0.592 rs3849967 chr10:75483366 C/T cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs10927875 0.541 rs1763601 chr1:16340460 G/T cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs6912958 0.559 rs395358 chr6:88057924 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.71 0.46 7.78e-8 Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs10034330 chr4:99064849 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.86 0.47 3.86e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10791097 0.694 rs11222369 chr11:130744670 A/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12477438 0.765 rs62154861 chr2:99590235 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.33 -0.49 4.13e-9 Chronic sinus infection; TGCT cis rs473651 0.935 rs578510 chr2:239343140 C/T cg21699342 chr2:239360505 ASB1 0.17 4.78 0.39 4.78e-6 Multiple system atrophy; TGCT cis rs9810089 0.934 rs66691851 chr3:136154828 C/T cg12473912 chr3:136751656 NA 0.34 4.96 0.41 2.3e-6 Gestational age at birth (child effect); TGCT cis rs10984561 0.881 rs7023869 chr9:122252359 C/A cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs9796 0.505 rs28665387 chr15:41532869 G/T cg18705301 chr15:41695430 NDUFAF1 -0.54 -6.9 -0.53 2.43e-10 Menopause (age at onset); TGCT trans rs561341 1.000 rs4795669 chr17:30244701 C/T cg20587970 chr11:113659929 NA -0.97 -11.47 -0.72 3.31e-21 Hip circumference adjusted for BMI; TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs904251 0.523 rs2797798 chr6:37481437 C/T cg25019722 chr6:37503610 NA -0.53 -8.19 -0.59 2.75e-13 Cognitive performance; TGCT cis rs2153535 0.601 rs7741024 chr6:8530313 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs2832191 0.633 rs2832166 chr21:30462395 G/C cg08807101 chr21:30365312 RNF160 0.65 6.02 0.48 1.82e-8 Dental caries; TGCT cis rs7000551 0.751 rs2469755 chr8:22360212 G/A cg12081754 chr8:22256438 SLC39A14 0.29 4.6 0.38 1.03e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10489202 0.913 rs380753 chr1:168035273 G/T cg24449463 chr1:168025552 DCAF6 -0.47 -5.26 -0.43 6.01e-7 Schizophrenia; TGCT cis rs7647973 0.961 rs7619016 chr3:49272589 C/T cg07636037 chr3:49044803 WDR6 0.7 5.69 0.45 8.73e-8 Menarche (age at onset); TGCT trans rs1814175 0.817 rs2866545 chr11:49630824 A/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.4 -0.6 8.93e-14 Height; TGCT cis rs28595532 0.920 rs114093638 chr4:119729819 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs1552244 0.882 rs13074282 chr3:10024699 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs9467773 1.000 rs767471 chr6:26557854 C/T cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs1023500 0.505 rs134878 chr22:42663874 A/G cg05082376 chr22:42548792 NA -0.21 -4.61 -0.38 9.93e-6 Schizophrenia; TGCT cis rs2361718 0.500 rs4889970 chr17:78096086 C/T cg21238619 chr17:78079768 GAA 0.38 4.71 0.39 6.59e-6 Yeast infection; TGCT trans rs1005277 0.579 rs2472178 chr10:38384750 T/C cg27523141 chr10:43048294 ZNF37B 0.71 8.31 0.6 1.4e-13 Extrinsic epigenetic age acceleration; TGCT cis rs8177179 0.904 rs1130459 chr3:133465283 A/G cg16262614 chr3:133464971 TF 0.34 4.57 0.38 1.15e-5 Iron status biomarkers (transferrin levels); TGCT cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs7611238 0.583 rs62288441 chr3:195151602 C/G cg27323046 chr3:195102265 ACAP2 0.39 5.14 0.42 1.05e-6 Body mass index; TGCT cis rs56235845 0.964 rs11741640 chr5:176792743 G/A cg06060754 chr5:176797920 RGS14 0.61 10.77 0.7 1.71e-19 Hemoglobin concentration;Hematocrit; TGCT cis rs7000551 0.751 rs2469770 chr8:22379856 G/A cg12081754 chr8:22256438 SLC39A14 0.28 4.53 0.38 1.36e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs3849570 0.565 rs1851926 chr3:81977231 A/C cg07356753 chr3:81810745 GBE1 -0.64 -5.61 -0.45 1.28e-7 Waist circumference;Body mass index; TGCT cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg12756686 chr19:29218302 NA 0.76 6.49 0.5 1.85e-9 Methadone dose in opioid dependence; TGCT cis rs7914558 0.966 rs7085598 chr10:104650128 T/C cg15744005 chr10:104629667 AS3MT -0.41 -5.09 -0.42 1.29e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg08048268 chr3:133502702 NA -0.53 -7.17 -0.54 5.89e-11 Iron status biomarkers; TGCT cis rs1062177 1.000 rs2915882 chr5:151145436 T/C cg00977110 chr5:151150581 G3BP1 0.4 4.62 0.38 9.43e-6 Preschool internalizing problems; TGCT cis rs9902453 0.967 rs34323226 chr17:28517454 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs2299587 0.554 rs7815429 chr8:17737357 T/C cg01800426 chr8:17659068 MTUS1 -0.57 -5.05 -0.41 1.57e-6 Economic and political preferences; TGCT cis rs73110464 0.562 rs2363634 chr12:53354683 A/G cg14581129 chr12:53358946 NA -0.63 -6.77 -0.52 4.65e-10 Cancer (pleiotropy); TGCT cis rs617219 0.671 rs6414979 chr5:78548010 T/G cg23514016 chr5:78407564 BHMT 0.34 5.09 0.42 1.29e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7107174 0.901 rs4945275 chr11:78119822 G/A cg12700464 chr11:78128424 GAB2 -0.61 -4.46 -0.37 1.85e-5 Testicular germ cell tumor; TGCT cis rs933688 1.000 rs2059208 chr5:90732065 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.25 0.6 1.91e-13 Smoking behavior; TGCT cis rs7208859 0.673 rs61223749 chr17:29163747 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6051080 1 rs6051080 chr20:25975674 A/G cg16686733 chr20:25566563 NINL 0.56 5.96 0.47 2.4e-8 Colorectal or endometrial cancer; TGCT cis rs9653442 0.527 rs11123812 chr2:100761548 T/C cg22139774 chr2:100720529 AFF3 -0.36 -5.72 -0.46 7.68e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7647973 0.626 rs4855882 chr3:49715354 G/T cg05785598 chr3:49045655 WDR6 0.42 4.98 0.41 2.06e-6 Menarche (age at onset); TGCT cis rs7428 0.962 rs3637 chr2:85549874 A/G cg24342717 chr2:85555507 TGOLN2 -0.4 -6.41 -0.5 2.8e-9 Ear protrusion; TGCT cis rs7666738 0.830 rs7678911 chr4:99057430 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.07 0.41 1.4e-6 Platelet count; TGCT cis rs16854884 0.837 rs4362712 chr3:143801076 G/A cg06585982 chr3:143692056 C3orf58 0.62 4.82 0.4 4.11e-6 Economic and political preferences (feminism/equality); TGCT cis rs6684514 1.000 rs12139321 chr1:156230429 A/G cg16558208 chr1:156270281 VHLL 0.46 8.56 0.61 3.68e-14 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9300255 0.602 rs1616131 chr12:123619838 G/A cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg08859206 chr1:53392774 SCP2 -0.42 -6.4 -0.5 2.95e-9 Monocyte count; TGCT cis rs10197940 0.624 rs13393122 chr2:152413315 A/G cg19508488 chr2:152266495 RIF1 0.7 6.44 0.5 2.36e-9 Lung cancer; TGCT cis rs2692947 0.537 rs11688045 chr2:96243805 A/T cg14612417 chr2:95688557 NA 0.37 4.68 0.39 7.34e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs902774 0.597 rs7299694 chr12:53352572 A/C cg05393297 chr12:53359155 NA -0.74 -8.08 -0.59 4.77e-13 Prostate cancer; TGCT cis rs981844 1.000 rs2251900 chr4:154654145 C/T cg14289246 chr4:154710475 SFRP2 1.01 7.95 0.58 9.84e-13 Response to statins (LDL cholesterol change); TGCT cis rs9291683 0.588 rs12647117 chr4:10022059 T/C cg11266682 chr4:10021025 SLC2A9 0.68 9.96 0.67 1.58e-17 Bone mineral density; TGCT cis rs12497850 0.644 rs11928552 chr3:48739883 T/C cg18654377 chr3:49208889 KLHDC8B -0.43 -5.76 -0.46 6.24e-8 Parkinson's disease; TGCT cis rs7586879 0.681 rs6545800 chr2:25118885 A/G cg01884057 chr2:25150051 NA -0.35 -6.9 -0.53 2.39e-10 Body mass index; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg12419862 chr22:24373484 LOC391322 0.91 8.2 0.59 2.51e-13 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6121246 0.567 rs6058189 chr20:30192389 A/G cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.42e-6 Mean corpuscular hemoglobin; TGCT cis rs2562456 0.917 rs9304987 chr19:21682274 A/T cg01304269 chr19:21688519 ZNF429 -0.58 -4.89 -0.4 3.06e-6 Pain; TGCT cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg20887711 chr4:1340912 KIAA1530 0.77 6.49 0.5 1.82e-9 Longevity; TGCT cis rs1055129 0.681 rs7221792 chr17:73834690 T/G cg10935138 chr17:73851978 WBP2 0.53 4.56 0.38 1.22e-5 White matter hyperintensity burden; TGCT cis rs138249 0.898 rs84504 chr22:50559247 G/A cg24864161 chr22:50528282 MOV10L1 0.47 5.02 0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs617219 0.671 rs2607144 chr5:78556798 G/T cg23514016 chr5:78407564 BHMT 0.36 5.24 0.43 6.81e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1903068 0.853 rs12498317 chr4:56007093 G/A cg01777861 chr4:56023843 NA 0.55 6.18 0.49 8.58e-9 Endometriosis; TGCT cis rs10883723 0.962 rs1056740 chr10:104236552 C/T cg05855489 chr10:104503620 C10orf26 -0.55 -4.68 -0.39 7.42e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9733 0.680 rs3738484 chr1:150552330 G/T cg13175981 chr1:150552382 MCL1 0.52 5.75 0.46 6.55e-8 Tonsillectomy; TGCT cis rs9517320 0.515 rs4772099 chr13:99196121 A/C cg07423050 chr13:99094983 FARP1 -0.27 -5.46 -0.44 2.52e-7 Longevity; TGCT cis rs2404602 0.655 rs3829489 chr15:77223256 A/C cg22467129 chr15:76604101 ETFA -0.5 -5.65 -0.45 1.06e-7 Blood metabolite levels; TGCT cis rs7729723 0.522 rs6596434 chr5:137815044 T/A cg19169342 chr5:137827400 NA 0.33 4.68 0.39 7.46e-6 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs116095464 0.558 rs13356367 chr5:242395 C/T cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs6952808 1.000 rs4601204 chr7:1890925 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.63 -0.45 1.13e-7 Bipolar disorder and schizophrenia; TGCT cis rs3806843 0.576 rs246029 chr5:140333226 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7819412 0.511 rs2409798 chr8:11435564 C/T cg21775007 chr8:11205619 TDH -0.53 -5.01 -0.41 1.8e-6 Triglycerides; TGCT cis rs9676308 0.677 rs74893436 chr19:57634972 G/A cg25972591 chr19:58627987 ZSCAN18 -0.5 -4.47 -0.37 1.73e-5 Colorectal cancer; TGCT cis rs992157 0.764 rs1870124 chr2:219187740 C/T cg00012203 chr2:219082015 ARPC2 0.71 6.65 0.51 8.23e-10 Colorectal cancer; TGCT cis rs2276314 0.857 rs62101394 chr18:33592299 C/T cg19628046 chr18:33552617 C18orf21 0.51 4.46 0.37 1.79e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs9913156 0.793 rs9436 chr17:4574751 T/A cg23387401 chr17:4582204 PELP1 0.31 4.59 0.38 1.09e-5 Lymphocyte counts; TGCT trans rs7819412 0.660 rs7462931 chr8:10910343 G/C cg06636001 chr8:8085503 FLJ10661 -0.74 -7.11 -0.54 8.3e-11 Triglycerides; TGCT cis rs1971762 0.762 rs7312853 chr12:54073597 C/G cg22546318 chr12:54070378 ATP5G2 0.31 4.46 0.37 1.79e-5 Height; TGCT cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg20607798 chr8:58055168 NA 0.45 4.59 0.38 1.06e-5 Developmental language disorder (linguistic errors); TGCT cis rs4944092 0.855 rs596339 chr11:75916507 T/C cg04588336 chr11:75916460 WNT11 -0.43 -5.89 -0.47 3.41e-8 PR interval; TGCT cis rs7714584 1.000 rs17800987 chr5:150323428 A/G cg22134413 chr5:150180641 NA 0.82 4.99 0.41 2.03e-6 Crohn's disease; TGCT cis rs826838 1.000 rs826891 chr12:39100824 A/G cg13010199 chr12:38710504 ALG10B -0.59 -4.88 -0.4 3.25e-6 Heart rate; TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg02073558 chr3:44770973 ZNF501 0.69 6.85 0.52 3.06e-10 Depressive symptoms; TGCT cis rs3733585 0.654 rs4447863 chr4:9938969 T/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.6 -0.56 6.41e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9814567 0.727 rs9809344 chr3:134342758 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -6.09 -0.48 1.3e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3796352 1.000 rs3806692 chr3:53080987 C/G cg07884673 chr3:53033167 SFMBT1 0.55 6.0 0.47 2.04e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs801193 0.967 rs34356500 chr7:66236607 G/T cg18876405 chr7:65276391 NA 0.35 5.1 0.42 1.24e-6 Aortic root size; TGCT cis rs4689388 0.926 rs10937718 chr4:6295217 T/C cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1005277 0.579 rs2505194 chr10:38393881 C/T cg25427524 chr10:38739819 LOC399744 -0.38 -7.92 -0.58 1.13e-12 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg07138768 chr7:917805 C7orf20 0.42 5.16 0.42 9.68e-7 Perceived unattractiveness to mosquitoes; TGCT trans rs1908814 0.503 rs34657250 chr8:11795373 A/G cg15556689 chr8:8085844 FLJ10661 -0.72 -6.65 -0.51 8.2e-10 Neuroticism; TGCT cis rs13188771 0.651 rs114484620 chr5:100889920 T/C cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs4780401 0.567 rs12920377 chr16:11781582 A/C cg01061890 chr16:11836724 TXNDC11 -0.44 -4.46 -0.37 1.82e-5 Rheumatoid arthritis; TGCT cis rs734999 0.869 rs1555791 chr1:2498862 G/C cg18854424 chr1:2615690 NA 0.46 5.62 0.45 1.18e-7 Ulcerative colitis; TGCT cis rs854765 0.547 rs4925135 chr17:17952868 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs6546537 1.000 rs12478540 chr2:69844524 C/T cg10773587 chr2:69614142 GFPT1 -0.77 -6.45 -0.5 2.31e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs7178572 0.524 rs2175941 chr15:77584498 T/C cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs727563 0.594 rs132807 chr22:42071584 T/C cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11626933 1.000 rs11621007 chr14:90743967 G/A cg14092571 chr14:90743983 NA -0.3 -6.18 -0.48 8.66e-9 Gut microbiota (bacterial taxa); TGCT cis rs1799949 0.931 rs9912203 chr17:41445145 A/G cg23758822 chr17:41437982 NA -0.71 -6.99 -0.53 1.49e-10 Menopause (age at onset); TGCT cis rs17221829 0.673 rs10830335 chr11:89403934 T/C cg02982614 chr11:89391479 FOLH1B -0.28 -4.67 -0.39 7.81e-6 Anxiety in major depressive disorder; TGCT cis rs644799 0.625 rs1255175 chr11:95471186 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.5 4.8 0.4 4.53e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7760949 0.889 rs9396272 chr6:13938080 C/T cg27413430 chr6:13925136 RNF182 -0.75 -6.91 -0.53 2.26e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs28595532 0.688 rs116566508 chr4:119619195 G/A cg11846333 chr4:119757529 SEC24D 0.92 5.01 0.41 1.85e-6 Cannabis dependence symptom count; TGCT cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg17179660 chr6:151773299 C6orf211;RMND1 -0.57 -5.38 -0.44 3.56e-7 Menarche (age at onset); TGCT cis rs1008375 1.000 rs1121090 chr4:17676437 C/G cg10189774 chr4:17578691 LAP3 0.53 5.0 0.41 1.91e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs56104184 0.578 rs7254608 chr19:49395774 G/T cg21252483 chr19:49399788 TULP2 -0.3 -5.05 -0.41 1.54e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2180341 0.694 rs2875972 chr6:127585522 T/C cg27446573 chr6:127587934 RNF146 0.98 8.94 0.63 4.63e-15 Breast cancer; TGCT cis rs2153535 0.601 rs1855765 chr6:8444325 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg13695892 chr22:41940480 POLR3H -0.87 -8.01 -0.58 6.94e-13 Vitiligo; TGCT cis rs7208859 0.673 rs11651802 chr17:29159660 T/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.830 rs4392515 chr4:98957431 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.554 rs74001399 chr2:238445440 G/A cg08992911 chr2:238395768 MLPH 0.64 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg13395646 chr4:1353034 KIAA1530 -0.41 -4.46 -0.37 1.78e-5 Longevity; TGCT cis rs7726839 0.540 rs7558 chr5:660491 C/T cg09021430 chr5:549028 NA -0.45 -6.19 -0.49 7.91e-9 Obesity-related traits; TGCT cis rs1008375 0.966 rs6839660 chr4:17667987 C/T cg18681998 chr4:17616180 MED28 0.9 10.37 0.68 1.6e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2486288 0.656 rs8039138 chr15:45551592 C/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs13326165 0.760 rs61150019 chr3:52354376 G/A cg07884673 chr3:53033167 SFMBT1 0.41 4.98 0.41 2.07e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6545883 0.826 rs1186697 chr2:61661417 G/A cg15711740 chr2:61764176 XPO1 -0.56 -4.99 -0.41 1.98e-6 Tuberculosis; TGCT cis rs12477438 0.765 rs62154861 chr2:99590235 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.99 -0.47 2.09e-8 Chronic sinus infection; TGCT cis rs1865760 0.892 rs6456705 chr6:25936056 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.15 0.48 9.9e-9 Height; TGCT cis rs858239 0.669 rs12539467 chr7:23115859 A/G cg05602783 chr7:23145260 KLHL7 -0.7 -5.94 -0.47 2.72e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs1008375 0.932 rs2302394 chr4:17641188 A/G cg18681998 chr4:17616180 MED28 0.96 10.38 0.68 1.51e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2204008 0.527 rs9804958 chr12:38192810 G/T cg26384229 chr12:38710491 ALG10B -0.54 -4.58 -0.38 1.12e-5 Bladder cancer; TGCT cis rs6967414 0.786 rs7782227 chr7:6748594 T/C cg00387323 chr7:6746715 ZNF12 0.79 4.92 0.4 2.67e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs11864453 0.713 rs2241412 chr16:72144284 A/G cg14768367 chr16:72042858 DHODH 0.51 4.95 0.41 2.32e-6 Fibrinogen levels; TGCT cis rs4680 0.737 rs4646312 chr22:19948337 C/T cg22546130 chr22:19950026 COMT 0.34 5.23 0.43 6.86e-7 Blood metabolite levels; TGCT cis rs950169 1.000 rs35297609 chr15:84772896 A/G cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.07e-8 Schizophrenia; TGCT cis rs617219 0.710 rs2166344 chr5:78534134 T/G cg05890484 chr5:78407552 BHMT 0.34 4.63 0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs806215 0.526 rs16871926 chr7:127517785 C/T cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.46e-6 Type 2 diabetes; TGCT cis rs5750830 0.649 rs6001588 chr22:39819049 G/C cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs9443189 0.526 rs10943255 chr6:76225928 T/A cg01950844 chr6:76311363 SENP6 0.94 5.69 0.46 8.52e-8 Prostate cancer; TGCT cis rs782590 0.837 rs2627769 chr2:55927288 G/C cg18811423 chr2:55921094 PNPT1 0.71 7.86 0.58 1.59e-12 Metabolic syndrome; TGCT cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg06221963 chr1:154839813 KCNN3 -0.74 -13.19 -0.76 2.3e-25 Prostate cancer; TGCT cis rs35306767 0.855 rs11253459 chr10:886402 C/T cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs72627509 0.638 rs78933653 chr4:57854840 A/G cg26694713 chr4:57773883 REST 0.62 4.59 0.38 1.06e-5 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7917772 0.582 rs6584512 chr10:104329685 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg22029157 chr1:209979665 IRF6 0.78 6.42 0.5 2.58e-9 Cleft lip with or without cleft palate; TGCT cis rs7833790 0.676 rs7834555 chr8:82697625 A/G cg06027949 chr8:82754900 SNX16 -0.6 -4.69 -0.39 7.14e-6 Diastolic blood pressure; TGCT cis rs7267979 0.932 rs431579 chr20:25470056 T/C cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.505 rs835609 chr1:53170494 T/C cg22166914 chr1:53195759 ZYG11B 0.45 7.68 0.57 4.04e-12 Monocyte count; TGCT cis rs514406 0.505 rs405208 chr1:53176674 C/T cg16325326 chr1:53192061 ZYG11B 0.86 12.25 0.74 4.3e-23 Monocyte count; TGCT trans rs7726839 0.540 rs61580655 chr5:597564 A/G cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs523395 0.630 rs616111 chr1:120269991 C/G cg19096424 chr1:120255104 PHGDH -0.48 -4.45 -0.37 1.9e-5 Red blood cell count; TGCT cis rs9457247 0.935 rs9348211 chr6:167375173 G/C cg23791538 chr6:167370224 RNASET2 0.53 5.19 0.42 8.41e-7 Crohn's disease; TGCT cis rs1008375 1.000 rs10009541 chr4:17682218 C/T cg18681998 chr4:17616180 MED28 -0.83 -8.43 -0.6 7.25e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.23 -0.43 6.93e-7 Tonsillectomy; TGCT cis rs9522267 0.535 rs914031 chr13:112240176 C/A cg10483660 chr13:112241077 NA -0.3 -5.02 -0.41 1.78e-6 Hepatitis; TGCT cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg08280861 chr8:58055591 NA 0.36 4.6 0.38 1.04e-5 Developmental language disorder (linguistic errors); TGCT cis rs4819052 0.807 rs28715237 chr21:46673768 C/G cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs950169 0.887 rs62029593 chr15:84955180 A/G cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs7474896 0.616 rs2474561 chr10:38373544 C/T cg25427524 chr10:38739819 LOC399744 -0.37 -5.16 -0.42 9.57e-7 Obesity (extreme); TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg13695892 chr22:41940480 POLR3H 0.87 8.24 0.59 2.06e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3796352 0.881 rs13100714 chr3:53074824 T/G cg07884673 chr3:53033167 SFMBT1 0.6 6.24 0.49 6.25e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9814567 1.000 rs6765505 chr3:134208132 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs950169 1.000 rs35648189 chr15:84740748 T/C cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.14e-8 Schizophrenia; TGCT cis rs10754283 0.967 rs1320563 chr1:90121032 G/A cg03145924 chr1:90228473 NA -0.4 -4.52 -0.38 1.4e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7772486 0.790 rs9497425 chr6:146234197 G/A cg23711669 chr6:146136114 FBXO30 -0.85 -9.7 -0.66 6.73e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs986417 0.901 rs1955690 chr14:61000492 A/G cg27398547 chr14:60952738 C14orf39 -1.22 -9.97 -0.67 1.52e-17 Gut microbiota (bacterial taxa); TGCT cis rs6912958 0.512 rs910563 chr6:88058885 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.68 6.88 0.53 2.68e-10 Monocyte percentage of white cells; TGCT cis rs4727443 0.691 rs6975827 chr7:99585798 C/G cg13334819 chr7:99746414 C7orf59 -0.57 -4.92 -0.4 2.71e-6 Interstitial lung disease; TGCT cis rs7954584 0.567 rs1720037 chr12:122382229 G/T cg21016266 chr12:122356598 WDR66 -0.49 -6.44 -0.5 2.35e-9 Mean corpuscular volume; TGCT cis rs7772486 0.738 rs9485039 chr6:146319387 C/T cg23711669 chr6:146136114 FBXO30 0.85 8.53 0.61 4.22e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs9393692 0.967 rs6456712 chr6:26302573 A/C cg00631329 chr6:26305371 NA -0.46 -6.92 -0.53 2.19e-10 Educational attainment; TGCT trans rs61931739 0.500 rs11053201 chr12:34453903 T/A cg26384229 chr12:38710491 ALG10B 0.73 6.92 0.53 2.09e-10 Morning vs. evening chronotype; TGCT cis rs7267979 0.903 rs6107015 chr20:25216764 G/A cg03522245 chr20:25566470 NINL 0.6 6.57 0.51 1.22e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg02073558 chr3:44770973 ZNF501 0.69 6.85 0.52 3.1e-10 Depressive symptoms; TGCT cis rs5750830 0.649 rs4821894 chr22:39809820 G/C cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs72781680 0.898 rs72786270 chr2:24059049 G/A cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs6089829 0.962 rs1060490 chr20:61665871 A/G cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.92 7.33 0.55 2.53e-11 Platelet count; TGCT cis rs6684514 1.000 rs6679145 chr1:156256000 T/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9527 0.614 rs2153774 chr10:104881035 T/C cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg17971929 chr21:40555470 PSMG1 -0.73 -6.87 -0.52 2.82e-10 Cognitive function; TGCT cis rs3733606 0.775 rs66514314 chr4:6827238 C/T cg18365211 chr4:7770554 AFAP1;LOC84740 0.32 4.5 0.37 1.56e-5 Platelet count; TGCT cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg18252515 chr7:66147081 NA -1.27 -7.54 -0.56 8.64e-12 Diabetic kidney disease; TGCT cis rs2469997 1.000 rs2470017 chr8:120361534 G/A cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs7937682 0.883 rs542831 chr11:111471392 T/A cg09085632 chr11:111637200 PPP2R1B -1.07 -11.36 -0.71 6.19e-21 Primary sclerosing cholangitis; TGCT cis rs2932538 0.922 rs9429694 chr1:113158289 G/A cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs11190604 1.000 rs3750627 chr10:102275642 G/T cg23241863 chr10:102295624 HIF1AN 0.66 5.01 0.41 1.82e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3806843 1.000 rs2098058 chr5:140157427 A/C cg19875535 chr5:140030758 IK -0.36 -6.01 -0.47 1.96e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs4642101 0.590 rs6799544 chr3:12812979 T/C cg05775895 chr3:12838266 CAND2 0.52 5.06 0.41 1.45e-6 QRS complex (12-leadsum); TGCT cis rs9858542 0.537 rs56038006 chr3:49362369 C/T cg00383909 chr3:49044727 WDR6 0.67 4.56 0.38 1.19e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1056107 0.931 rs2027384 chr9:115000234 G/A cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs2204008 0.654 rs1290325 chr12:38152910 C/T cg26384229 chr12:38710491 ALG10B -0.63 -5.69 -0.46 8.47e-8 Bladder cancer; TGCT cis rs3008870 1.000 rs3008854 chr1:67385951 T/C cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs2836974 0.666 rs4818015 chr21:40675493 A/C cg11644478 chr21:40555479 PSMG1 0.64 6.35 0.5 3.61e-9 Cognitive function; TGCT cis rs28493229 0.708 rs10408310 chr19:41161190 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs72945132 0.882 rs72949081 chr11:70219070 A/G cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs903263 0.601 rs11163900 chr1:84557569 G/A cg09664975 chr1:84543551 PRKACB 0.5 4.86 0.4 3.47e-6 Breast cancer (male); TGCT cis rs6088590 0.710 rs6059992 chr20:33282275 T/C cg08999081 chr20:33150536 PIGU 0.26 4.88 0.4 3.17e-6 Coronary artery disease; TGCT cis rs1008375 0.900 rs10019460 chr4:17686337 T/C cg10189774 chr4:17578691 LAP3 -0.56 -4.89 -0.4 3.01e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9303401 0.527 rs2116450 chr17:56745561 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.61 5.41 0.44 3.12e-7 Cognitive test performance; TGCT cis rs12893668 0.703 rs7140568 chr14:104041374 C/T cg26031613 chr14:104095156 KLC1 -0.54 -4.44 -0.37 1.97e-5 Reticulocyte count; TGCT cis rs9682041 0.627 rs3772172 chr3:170077713 C/T cg07589077 chr3:170072950 NA -0.27 -4.66 -0.39 8.08e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs80282103 0.867 rs80254477 chr10:1077387 T/G cg15531433 chr10:1639090 ADARB2 0.41 4.5 0.37 1.52e-5 Glomerular filtration rate (creatinine); TGCT cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg05025164 chr4:1340916 KIAA1530 0.74 6.14 0.48 1.02e-8 Longevity; TGCT cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs6978712 1.000 rs7789577 chr7:127150498 C/T cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs7829975 0.653 rs13259070 chr8:8690787 C/T cg06636001 chr8:8085503 FLJ10661 0.74 6.57 0.51 1.25e-9 Mood instability; TGCT cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs79149102 0.579 rs58294763 chr15:75299768 G/A cg09165964 chr15:75287851 SCAMP5 -1.06 -5.71 -0.46 7.92e-8 Lung cancer; TGCT cis rs9894429 0.646 rs8080391 chr17:79566319 A/T cg18240062 chr17:79603768 NPLOC4 -0.84 -9.67 -0.66 8.03e-17 Eye color traits; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg18110333 chr6:292329 DUSP22 -0.71 -7.67 -0.57 4.25e-12 Menopause (age at onset); TGCT cis rs7833790 0.963 rs2400473 chr8:82703403 C/T cg17211192 chr8:82754475 SNX16 -1.14 -8.89 -0.62 5.9e-15 Diastolic blood pressure; TGCT cis rs3782455 1.000 rs16943545 chr12:114406337 T/C cg10631684 chr12:113795897 PLBD2 -0.78 -5.28 -0.43 5.52e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs981844 0.857 rs62325140 chr4:154714161 C/A cg14289246 chr4:154710475 SFRP2 1.04 8.85 0.62 7.29e-15 Response to statins (LDL cholesterol change); TGCT cis rs71435601 0.600 rs312982 chr2:21378226 G/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs10883723 0.810 rs2296590 chr10:104262628 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1153858 1.000 rs2066090 chr15:45650018 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs5769765 0.955 rs5769761 chr22:50263641 G/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg02891314 chr5:179741120 GFPT2 -0.41 -7.09 -0.54 8.78e-11 Height; TGCT cis rs2180341 0.960 rs7766942 chr6:127691323 G/T cg27446573 chr6:127587934 RNF146 1.1 10.61 0.69 4.22e-19 Breast cancer; TGCT cis rs611744 0.967 rs569701 chr8:109239207 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs9814567 0.752 rs9836401 chr3:134336897 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.72 -6.5 -0.5 1.78e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6565180 1.000 rs8049108 chr16:30376486 A/G cg17640201 chr16:30407289 ZNF48 -0.87 -8.85 -0.62 7.53e-15 Tonsillectomy; TGCT cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg24531977 chr5:56204891 C5orf35 -0.76 -7.66 -0.57 4.53e-12 Initial pursuit acceleration; TGCT cis rs4820539 1.000 rs756631 chr22:23463183 A/G cg21100191 chr22:23484243 RTDR1 0.92 10.84 0.7 1.13e-19 Bone mineral density; TGCT cis rs10744422 0.764 rs4038080 chr12:123292915 T/C cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs7713065 0.531 rs2522051 chr5:131797578 C/T cg24060327 chr5:131705240 SLC22A5 -0.51 -5.01 -0.41 1.8e-6 Lung function (FEV1/FVC); TGCT cis rs6993813 0.620 rs6469802 chr8:120029323 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs7169223 0.653 rs1994017 chr15:79080306 T/C cg21242079 chr15:79101063 ADAMTS7 0.32 5.31 0.43 4.92e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg12310025 chr6:25882481 NA -0.67 -5.89 -0.47 3.36e-8 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs858239 0.669 rs6461687 chr7:23116580 A/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.39 -0.44 3.47e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6582630 0.519 rs11514056 chr12:38284001 G/T cg13010199 chr12:38710504 ALG10B 0.59 4.61 0.38 9.88e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9584850 0.834 rs3783005 chr13:99111337 A/T cg15168958 chr13:99100528 FARP1 0.23 4.58 0.38 1.12e-5 Neuroticism; TGCT cis rs853679 0.506 rs1150711 chr6:28208535 T/C cg13525197 chr6:28411240 ZSCAN23 -0.45 -4.43 -0.37 2.01e-5 Depression; TGCT cis rs6121246 0.522 rs6088736 chr20:30195166 C/G cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg11003573 chr3:44754125 ZNF502 -0.48 -5.75 -0.46 6.47e-8 Depressive symptoms; TGCT cis rs9894429 0.934 rs35868252 chr17:79575472 C/G cg21028142 chr17:79581711 NPLOC4 -0.29 -6.81 -0.52 3.83e-10 Eye color traits; TGCT cis rs10479542 0.929 rs10074573 chr5:178976966 C/T cg00080972 chr5:178986291 RUFY1 -0.45 -5.24 -0.43 6.73e-7 Lung cancer; TGCT cis rs7727544 0.836 rs10463892 chr5:131598705 T/C cg24060327 chr5:131705240 SLC22A5 -0.6 -6.4 -0.5 2.92e-9 Blood metabolite levels; TGCT cis rs7552404 0.924 rs1858536 chr1:76161595 G/T cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12484776 0.729 rs8140112 chr22:40533130 A/G cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs7772486 0.754 rs13214277 chr6:146136125 G/T cg13319975 chr6:146136371 FBXO30 -0.57 -5.1 -0.42 1.22e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9308731 0.966 rs4848393 chr2:111877297 T/C cg04202892 chr2:111875749 ACOXL 0.43 4.58 0.38 1.1e-5 Chronic lymphocytic leukemia; TGCT trans rs1974653 0.672 rs9606239 chr22:20070285 G/A cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs13188771 0.690 rs12519215 chr5:100898218 A/G cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7226408 0.857 rs72885260 chr18:34431004 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs875971 1.000 rs7801282 chr7:65613687 C/T cg11764359 chr7:65958608 NA -0.59 -5.28 -0.43 5.5e-7 Aortic root size; TGCT cis rs2153535 0.580 rs4639392 chr6:8446547 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs9818758 0.505 rs11716159 chr3:49631585 G/A cg08550065 chr3:50336684 HYAL3;NAT6 1.04 5.13 0.42 1.08e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7666738 0.830 rs10005173 chr4:98816062 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.25 0.43 6.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs826838 0.967 rs2892410 chr12:38990282 A/G cg13010199 chr12:38710504 ALG10B -0.74 -6.17 -0.48 8.84e-9 Heart rate; TGCT cis rs9818758 0.607 rs71324929 chr3:49044713 C/T cg07636037 chr3:49044803 WDR6 -1.04 -4.98 -0.41 2.07e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs868036 0.718 rs922494 chr15:68120644 T/C cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs929354 0.772 rs10229630 chr7:157004790 C/T cg05182265 chr7:156933206 UBE3C -0.37 -8.4 -0.6 8.86e-14 Body mass index; TGCT cis rs4819052 0.851 rs35064782 chr21:46674360 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.59 4.71 0.39 6.6e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7582180 0.629 rs4851296 chr2:100949570 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.95 -0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT cis rs1800469 1.000 rs1800469 chr19:41860296 A/G cg09537434 chr19:41945824 ATP5SL -0.5 -4.58 -0.38 1.09e-5 Colorectal cancer; TGCT cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg17971929 chr21:40555470 PSMG1 -0.67 -6.29 -0.49 5.06e-9 Cognitive function; TGCT cis rs4654899 1.000 rs4654902 chr1:21435056 T/G cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs9393777 0.720 rs36022097 chr6:26995168 G/A cg16898833 chr6:26189333 HIST1H4D 0.97 5.95 0.47 2.6e-8 Intelligence (multi-trait analysis); TGCT cis rs59104589 0.959 rs3771555 chr2:242322680 C/T cg21155796 chr2:242212141 HDLBP -0.55 -4.75 -0.39 5.56e-6 Fibrinogen levels; TGCT cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.89 -10.59 -0.69 4.52e-19 Colorectal cancer; TGCT cis rs6088580 0.609 rs6059844 chr20:33036482 A/G cg24642439 chr20:33292090 TP53INP2 0.47 4.47 0.37 1.75e-5 Glomerular filtration rate (creatinine); TGCT cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg06481639 chr22:41940642 POLR3H -0.74 -6.51 -0.5 1.71e-9 Vitiligo; TGCT cis rs4900538 0.855 rs60215817 chr14:102873886 A/G cg18135206 chr14:102964638 TECPR2 -0.2 -4.55 -0.38 1.24e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2439831 1.000 rs689781 chr15:43792097 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.19 0.59 2.67e-13 Lung cancer in ever smokers; TGCT cis rs6138458 0.626 rs6050261 chr20:25014206 C/T cg26195577 chr20:24973756 C20orf3 0.99 9.24 0.64 8.46e-16 Blood protein levels; TGCT cis rs7662987 0.517 rs2602858 chr4:100030461 T/C cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs4699052 0.963 rs7672802 chr4:104212233 A/T cg16532752 chr4:104119610 CENPE -0.56 -5.1 -0.42 1.26e-6 Testicular germ cell tumor; TGCT cis rs3008870 0.959 rs4655658 chr1:67389608 C/T cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs4901869 0.966 rs12893803 chr14:59329655 T/C cg02291164 chr14:59296302 NA 0.26 4.97 0.41 2.21e-6 Panic disorder; TGCT cis rs10927875 0.832 rs4661342 chr1:16160773 C/G cg21385522 chr1:16154831 NA -0.89 -11.06 -0.7 3.27e-20 Dilated cardiomyopathy; TGCT cis rs7586879 0.575 rs6744205 chr2:25133148 T/C cg15423357 chr2:25149977 NA 0.52 5.04 0.41 1.63e-6 Body mass index; TGCT cis rs11696501 0.694 rs6073823 chr20:44256910 G/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs4819052 0.590 rs414743 chr21:46512075 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.61 4.69 0.39 7.09e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs344364 0.602 rs2983907 chr16:1913336 C/T cg01422476 chr16:1922425 C16orf73 -0.47 -4.52 -0.38 1.43e-5 Glomerular filtration rate in chronic kidney disease; TGCT cis rs3820068 0.705 rs2042369 chr1:15843244 A/G cg05660106 chr1:15850417 CASP9 -1.17 -13.71 -0.78 1.29e-26 Systolic blood pressure; TGCT cis rs9818758 0.607 rs56306491 chr3:49314960 G/A cg07636037 chr3:49044803 WDR6 -1.01 -4.93 -0.4 2.63e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6967414 0.786 rs7804259 chr7:6755448 C/G cg09896999 chr7:6746977 ZNF12 -0.59 -6.54 -0.51 1.45e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs36051895 0.587 rs7019418 chr9:5259847 G/C cg02405213 chr9:5042618 JAK2 -0.71 -9.72 -0.66 6.17e-17 Pediatric autoimmune diseases; TGCT cis rs1483890 0.723 rs13077078 chr3:69411402 C/A cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs372883 0.638 rs371432 chr21:30710876 G/A cg24692254 chr21:30365293 RNF160 -0.54 -4.85 -0.4 3.62e-6 Pancreatic cancer; TGCT cis rs3733585 0.699 rs17245723 chr4:9962218 A/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.38 -0.5 3.14e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg06873352 chr17:61820015 STRADA 0.55 6.03 0.48 1.71e-8 Prudent dietary pattern; TGCT cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg00149659 chr3:10157352 C3orf10 1.04 5.76 0.46 6.32e-8 Alzheimer's disease; TGCT cis rs8177253 0.509 rs6762415 chr3:133478557 T/G cg01448562 chr3:133502909 NA -0.32 -5.57 -0.45 1.51e-7 Iron status biomarkers; TGCT cis rs1008375 0.966 rs6832414 chr4:17696866 C/G cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs8014204 0.762 rs10138360 chr14:75293386 A/G cg06637938 chr14:75390232 RPS6KL1 -0.54 -4.9 -0.4 2.95e-6 Caffeine consumption; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg09704166 chr2:114031854 PAX8;LOC440839 -0.32 -4.82 -0.4 4.04e-6 Lymphocyte counts; TGCT cis rs12477438 0.834 rs1563108 chr2:99701153 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.92 -9.58 -0.65 1.29e-16 Chronic sinus infection; TGCT cis rs9303401 0.659 rs62083525 chr17:56658088 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs10751667 0.961 rs6597951 chr11:991530 C/T cg06064525 chr11:970664 AP2A2 -0.3 -6.04 -0.48 1.64e-8 Alzheimer's disease (late onset); TGCT cis rs597539 0.652 rs514296 chr11:68654182 G/T cg04772025 chr11:68637568 NA 0.59 6.61 0.51 1.04e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17376456 0.877 rs12374470 chr5:93481046 A/G cg25358565 chr5:93447407 FAM172A 0.97 8.35 0.6 1.16e-13 Diabetic retinopathy; TGCT cis rs1949733 0.656 rs2631762 chr4:8423122 A/T cg13073564 chr4:8508604 NA -0.41 -4.49 -0.37 1.63e-5 Response to antineoplastic agents; TGCT cis rs1799949 1.000 rs35070007 chr17:41316747 C/G cg10047753 chr17:41438598 NA -0.78 -7.41 -0.55 1.68e-11 Menopause (age at onset); TGCT cis rs2153535 0.562 rs9379211 chr6:8463927 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs559928 0.606 rs57021319 chr11:63956102 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.57 0.38 1.18e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs10089 1.000 rs3816006 chr5:127450581 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs4919669 0.668 rs17114810 chr10:104391545 C/T cg05855489 chr10:104503620 C10orf26 0.74 4.73 0.39 5.9e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs9916302 0.904 rs9898773 chr17:37532507 C/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs2439831 0.867 rs2470134 chr15:43849886 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.85 -5.33 -0.43 4.52e-7 Lung cancer in ever smokers; TGCT cis rs12048904 0.964 rs12027668 chr1:101330984 G/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 4.54 0.38 1.31e-5 Multiple sclerosis; TGCT cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg23248424 chr5:179741104 GFPT2 -0.38 -7.0 -0.53 1.41e-10 Height; TGCT cis rs56104184 0.775 rs73061692 chr19:49399676 T/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs10114408 0.959 rs1890379 chr9:96665767 A/G cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs67311347 1.000 rs9841335 chr3:40475858 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs7809950 0.954 rs2520241 chr7:107135443 A/G cg23024343 chr7:107201750 COG5 -0.33 -5.16 -0.42 9.43e-7 Coronary artery disease; TGCT trans rs4919669 0.582 rs4919649 chr10:104272336 T/C cg19053889 chr7:1098703 C7orf50;GPR146 0.51 6.78 0.52 4.25e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs2758596 1.000 rs2842866 chr1:156159721 G/A cg24450063 chr1:156163899 SLC25A44 0.8 4.65 0.39 8.25e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs7666738 0.830 rs13108871 chr4:98803872 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.64 0.45 1.11e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.731 rs6846966 chr4:120293208 A/G cg09307838 chr4:120376055 NA 0.57 5.56 0.45 1.6e-7 Corneal astigmatism; TGCT cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg17747265 chr1:1875780 NA -0.3 -5.07 -0.41 1.42e-6 Body mass index; TGCT cis rs9291683 0.588 rs11732054 chr4:9999877 C/T cg00071950 chr4:10020882 SLC2A9 0.7 9.28 0.64 6.94e-16 Bone mineral density; TGCT cis rs1555895 0.599 rs12243303 chr10:861390 C/T cg02193355 chr10:851439 NA 0.25 5.62 0.45 1.22e-7 Survival in rectal cancer; TGCT cis rs12620999 1.000 rs12620999 chr2:238036367 C/T cg23555395 chr2:238036564 NA -0.31 -5.51 -0.44 2.02e-7 Systemic lupus erythematosus; TGCT cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg18230493 chr5:56204884 C5orf35 0.68 5.92 0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs854624 0.792 rs2687497 chr17:34335167 T/C cg02022384 chr17:34097390 MMP28 0.49 4.55 0.38 1.28e-5 Blood protein levels; TGCT cis rs2857078 0.654 rs4793083 chr17:42312973 C/T cg13607699 chr17:42295918 UBTF -0.96 -9.88 -0.66 2.46e-17 Red cell distribution width;Reticulocyte count; TGCT cis rs11641365 0.678 rs877579 chr16:88770621 A/G cg09735908 chr16:88770558 RNF166 -0.27 -4.49 -0.37 1.61e-5 Autism spectrum disorder-related traits; TGCT cis rs9291683 0.588 rs35438220 chr4:9999398 C/T cg00071950 chr4:10020882 SLC2A9 0.7 9.28 0.64 6.94e-16 Bone mineral density; TGCT trans rs561341 0.623 rs4795665 chr17:30233657 C/T cg20587970 chr11:113659929 NA -0.68 -9.46 -0.65 2.55e-16 Hip circumference adjusted for BMI; TGCT trans rs797680 0.856 rs2031226 chr1:93786764 G/T cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9911578 1.000 rs2531732 chr17:56548420 T/A cg05425664 chr17:57184151 TRIM37 0.63 6.21 0.49 7.48e-9 Intelligence (multi-trait analysis); TGCT cis rs4700695 0.614 rs251285 chr5:65211137 A/T cg21114390 chr5:65439923 SFRS12 0.62 4.44 0.37 1.99e-5 Facial morphology (factor 19); TGCT cis rs7246657 0.943 rs10417844 chr19:37837587 C/T cg03233940 chr19:37894644 NA -0.34 -4.49 -0.37 1.59e-5 Coronary artery calcification; TGCT cis rs4851266 1.000 rs1160543 chr2:100832182 C/T cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs17401966 0.931 rs1002076 chr1:10438892 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs12541335 0.639 rs7834182 chr8:22163112 G/A cg09517075 chr8:22133004 PIWIL2 0.25 4.99 0.41 1.95e-6 Hypertriglyceridemia; TGCT cis rs9457247 1.000 rs400176 chr6:167406238 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs11105298 0.891 rs10858899 chr12:89923811 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2535633 0.631 rs6799185 chr3:53101580 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.84 -0.4 3.73e-6 Body mass index; TGCT cis rs2013441 0.932 rs2526488 chr17:20098617 T/A cg23224458 chr17:20280056 CCDC144C -0.37 -4.46 -0.37 1.83e-5 Obesity-related traits; TGCT cis rs881375 0.967 rs2109896 chr9:123683106 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.47 5.24 0.43 6.64e-7 Rheumatoid arthritis; TGCT cis rs9467711 0.790 rs13220495 chr6:26441640 C/T cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7605378 1.000 rs7605378 chr2:200676926 A/C cg23649088 chr2:200775458 C2orf69 0.33 5.61 0.45 1.25e-7 Osteoporosis; TGCT cis rs12477438 0.559 rs6733285 chr2:99725575 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs2180341 0.521 rs12189967 chr6:127718058 G/A cg24812749 chr6:127587940 RNF146 0.61 5.25 0.43 6.27e-7 Breast cancer; TGCT cis rs137603 0.644 rs137620 chr22:39709776 T/C cg17798944 chr22:39715225 SNORD43;RPL3 -0.68 -7.19 -0.54 5.24e-11 Primary biliary cholangitis; TGCT cis rs9549260 0.755 rs2701869 chr13:41157372 G/A cg21288729 chr13:41239152 FOXO1 1.0 10.06 0.67 9.29e-18 Red blood cell count; TGCT cis rs765787 0.530 rs12915804 chr15:45512562 T/C cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT cis rs4663866 0.901 rs76312449 chr2:239190906 A/G cg17283117 chr2:239148619 HES6 1.01 4.66 0.39 8.09e-6 Irritable bowel syndrome; TGCT cis rs4862750 0.914 rs6837117 chr4:187872379 C/T cg03452623 chr4:187889614 NA -0.36 -5.24 -0.43 6.6e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg10819733 chr22:24237672 NA -0.28 -4.51 -0.38 1.49e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs524281 0.861 rs9645684 chr11:65907964 G/A cg00563793 chr11:65837595 PACS1 0.57 4.79 0.39 4.77e-6 Electroencephalogram traits; TGCT cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs9303401 0.625 rs34963822 chr17:56988424 C/A cg25039879 chr17:56429692 SUPT4H1 0.52 4.57 0.38 1.15e-5 Cognitive test performance; TGCT trans rs629535 0.773 rs72654090 chr8:70118666 G/A cg21567404 chr3:27674614 NA -0.56 -9.04 -0.63 2.69e-15 Dupuytren's disease; TGCT cis rs4722585 0.533 rs12334205 chr7:26202490 G/A cg03781084 chr7:26191726 NFE2L3 -0.45 -4.53 -0.38 1.39e-5 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs7312933 0.558 rs61926593 chr12:42818912 C/T cg19980929 chr12:42632907 YAF2 0.42 5.91 0.47 3.05e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7611238 0.560 rs9846555 chr3:195114549 G/T cg27323046 chr3:195102265 ACAP2 0.39 5.13 0.42 1.08e-6 Body mass index; TGCT cis rs1371867 0.846 rs1616833 chr8:101271821 C/T cg06636551 chr8:101224915 SPAG1 0.43 5.95 0.47 2.58e-8 Atrioventricular conduction; TGCT cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs7312933 0.703 rs10880264 chr12:42586535 A/G cg19980929 chr12:42632907 YAF2 0.45 6.29 0.49 4.84e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6671200 1.000 rs259359 chr1:95709039 A/G cg26537280 chr1:95699037 RWDD3 -0.69 -5.49 -0.44 2.19e-7 Stearic acid (18:0) levels; TGCT cis rs4455778 0.561 rs13243449 chr7:49129765 T/C cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs4851266 0.898 rs12053126 chr2:100864646 A/T cg07810366 chr2:100720526 AFF3 -0.39 -5.89 -0.47 3.35e-8 Educational attainment; TGCT cis rs12510870 0.599 rs10011419 chr4:74453691 T/C cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs12477438 0.798 rs12468419 chr2:99579680 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.79 -7.94 -0.58 1.06e-12 Chronic sinus infection; TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg02953382 chr22:24373134 LOC391322 -0.81 -9.11 -0.63 1.79e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7412746 0.611 rs2271076 chr1:150916657 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs2549003 0.966 rs10072571 chr5:131816711 A/C cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs2153535 0.541 rs9405386 chr6:8458067 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.7 0.46 8.33e-8 Motion sickness; TGCT cis rs7666738 0.830 rs4492007 chr4:98959848 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg23982607 chr1:1823379 GNB1 -0.55 -8.34 -0.6 1.23e-13 Body mass index; TGCT cis rs10782582 0.593 rs79552201 chr1:76215497 A/T cg10523679 chr1:76189770 ACADM -0.67 -6.71 -0.52 6.18e-10 Daytime sleep phenotypes; TGCT cis rs1475911 0.708 rs11701371 chr21:43523972 C/G cg24372256 chr21:43528868 UMODL1;C21orf128 -0.31 -5.91 -0.47 3.08e-8 IgG glycosylation; TGCT cis rs2153535 0.580 rs9328484 chr6:8524843 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs7412746 0.586 rs2864882 chr1:150883037 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs6089829 1.000 rs6089829 chr20:61669036 C/T cg03213289 chr20:61660250 NA -0.64 -8.48 -0.61 5.78e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs12548939 0.560 rs4733803 chr8:128907875 G/A cg11792826 chr8:129160931 MIR1208 0.2 4.54 0.38 1.32e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2956278 0.717 rs2947126 chr12:84687359 T/C cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs6089829 0.926 rs6011552 chr20:61667894 T/C cg02380750 chr20:61661411 NA 0.34 5.96 0.47 2.47e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs634534 0.622 rs531612 chr11:65705432 C/T cg04055107 chr11:65626734 MUS81;CFL1 -0.5 -5.11 -0.42 1.19e-6 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7027203 1.000 rs34624092 chr9:96523092 G/A cg13679303 chr9:96623674 NA 0.64 9.79 0.66 4.09e-17 DNA methylation (variation); TGCT cis rs600231 0.651 rs2846862 chr11:65219790 A/G cg11802864 chr11:65308245 LTBP3 0.46 4.59 0.38 1.07e-5 Bone mineral density; TGCT cis rs858239 1.000 rs199348 chr7:23293098 C/A cg05602783 chr7:23145260 KLHL7 -0.6 -4.83 -0.4 3.97e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9894429 0.752 rs6565610 chr17:79592652 A/G cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT cis rs11585357 1.000 rs72646785 chr1:17603472 G/T cg08277548 chr1:17600880 PADI3 -0.97 -9.95 -0.67 1.7e-17 Hair shape; TGCT cis rs11190604 0.767 rs11190531 chr10:102187310 T/A cg16005271 chr10:102321736 NA 0.46 4.67 0.39 7.62e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4713118 0.621 rs4713133 chr6:28034041 T/C cg12963246 chr6:28129442 ZNF389 0.48 4.79 0.4 4.58e-6 Parkinson's disease; TGCT cis rs4595586 0.545 rs2197941 chr12:39402223 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs57221529 0.766 rs4081846 chr5:574019 G/A cg20362242 chr5:692897 TPPP 0.5 4.71 0.39 6.66e-6 Lung disease severity in cystic fibrosis; TGCT cis rs4665809 0.590 rs2384361 chr2:26452209 T/C cg25036284 chr2:26402008 FAM59B -0.67 -5.32 -0.43 4.71e-7 Gut microbiome composition (summer); TGCT cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg18876405 chr7:65276391 NA 0.37 5.85 0.47 4.02e-8 Calcium levels; TGCT cis rs3806843 0.766 rs702397 chr5:140050265 A/G cg19875535 chr5:140030758 IK -0.35 -5.95 -0.47 2.61e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2153535 0.580 rs6597337 chr6:8531652 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs6121246 0.908 rs17093657 chr20:30428894 G/A cg13852791 chr20:30311386 BCL2L1 0.76 5.67 0.45 9.7e-8 Mean corpuscular hemoglobin; TGCT cis rs9372253 1.000 rs9386894 chr6:110718853 A/G cg13266496 chr6:110720918 DDO -0.48 -5.82 -0.46 4.76e-8 Platelet distribution width; TGCT cis rs6912958 0.712 rs2307379 chr6:88366771 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.6 -0.38 1.04e-5 Monocyte percentage of white cells; TGCT cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg16049864 chr8:95962084 TP53INP1 -0.75 -10.47 -0.69 8.97e-19 Type 2 diabetes; TGCT cis rs10892173 0.566 rs2298649 chr11:117672225 A/G cg21640587 chr11:117668038 DSCAML1 0.71 8.27 0.6 1.73e-13 Myopia; TGCT cis rs4727027 0.800 rs10952796 chr7:148813138 G/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.6 0.38 1.04e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.83 0.46 4.52e-8 Schizophrenia; TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs597539 0.552 rs6591360 chr11:68718669 G/T cg06112835 chr11:68658793 MRPL21 0.46 7.64 0.57 5.15e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs753778 0.570 rs6985866 chr8:142210336 C/T cg18755752 chr8:142205143 DENND3 0.26 5.05 0.41 1.54e-6 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4499344 0.604 rs259275 chr19:33159693 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs7909074 0.898 rs10793565 chr10:45388231 G/C cg04218760 chr10:45406644 TMEM72 -0.28 -5.66 -0.45 1.01e-7 Mean corpuscular volume; TGCT cis rs6500602 0.647 rs1684600 chr16:4594671 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.31 -5.88 -0.47 3.62e-8 Schizophrenia; TGCT cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg20637647 chr7:64974828 NA 0.89 5.39 0.44 3.46e-7 Diabetic kidney disease; TGCT cis rs17102423 0.660 rs7152277 chr14:65535391 G/C cg11161011 chr14:65562177 MAX -0.46 -6.12 -0.48 1.11e-8 Obesity-related traits; TGCT cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg04352962 chr1:209979756 IRF6 0.69 5.07 0.41 1.39e-6 Cleft lip with or without cleft palate; TGCT cis rs9913156 0.894 rs28365158 chr17:4620928 T/C cg19197139 chr17:4613644 ARRB2 0.86 7.84 0.58 1.73e-12 Lymphocyte counts; TGCT cis rs1371867 0.846 rs1788194 chr8:101277916 T/C cg06002616 chr8:101225028 SPAG1 -0.57 -6.77 -0.52 4.48e-10 Atrioventricular conduction; TGCT cis rs796364 1.000 rs35594306 chr2:200775125 T/C cg17644776 chr2:200775616 C2orf69 -0.31 -4.83 -0.4 3.99e-6 Schizophrenia; TGCT cis rs3008870 0.755 rs2208577 chr1:67513574 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.8 7.47 0.56 1.28e-11 Lymphocyte percentage of white cells; TGCT cis rs6598955 0.724 rs12132137 chr1:26631243 C/T cg04990556 chr1:26633338 UBXN11 -0.92 -12.21 -0.74 5.2e-23 Obesity-related traits; TGCT cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg17554472 chr22:41940697 POLR3H -0.49 -5.29 -0.43 5.45e-7 Vitiligo; TGCT cis rs7914558 1.000 rs10883824 chr10:104812897 A/G cg04362960 chr10:104952993 NT5C2 0.62 5.51 0.44 1.97e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT trans rs365060 0.749 rs260687 chr2:109578855 C/T cg13735819 chr19:2253850 JSRP1 -0.7 -6.65 -0.51 8.52e-10 Beard thickness; TGCT cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg13695892 chr22:41940480 POLR3H 0.92 9.06 0.63 2.36e-15 Vitiligo; TGCT cis rs12477438 0.520 rs1133978 chr2:99741964 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg13257436 chr8:145726034 PPP1R16A -0.31 -4.82 -0.4 4.04e-6 Age at first birth; TGCT cis rs651907 0.535 rs35799195 chr3:101521927 A/G cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs3733585 0.673 rs6836706 chr4:9964251 T/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10876993 0.622 rs7978394 chr12:58091695 C/A cg15848620 chr12:58087721 OS9 -0.76 -6.37 -0.5 3.3e-9 Celiac disease or Rheumatoid arthritis; TGCT cis rs861020 0.630 rs655712 chr1:210006437 G/A cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs7312933 0.533 rs11181499 chr12:42818761 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.14 0.42 1.06e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7364180 0.515 rs6002503 chr22:42208672 A/G cg03806693 chr22:41940476 POLR3H -0.63 -6.26 -0.49 5.79e-9 Alzheimer's disease biomarkers; TGCT cis rs2862064 0.872 rs1393209 chr5:156477540 G/A cg12943317 chr5:156479607 HAVCR1 -0.46 -5.59 -0.45 1.35e-7 Platelet count; TGCT cis rs2439831 0.850 rs8042868 chr15:43939642 C/T cg19166733 chr15:44192098 FRMD5 -0.25 -4.62 -0.38 9.4e-6 Lung cancer in ever smokers; TGCT cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg20203395 chr5:56204925 C5orf35 -0.56 -4.8 -0.4 4.39e-6 Initial pursuit acceleration; TGCT cis rs8064299 0.655 rs2305214 chr17:72768970 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.62 5.76 0.46 6.21e-8 Monocyte count; TGCT cis rs7027203 0.576 rs4509402 chr9:96543377 C/T cg14598338 chr9:96623480 NA 0.49 7.16 0.54 6.37e-11 DNA methylation (variation); TGCT cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg06481639 chr22:41940642 POLR3H -0.73 -6.64 -0.51 8.91e-10 Vitiligo; TGCT cis rs2120019 1.000 rs7168680 chr15:75369212 G/A cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg16524733 chr11:117070046 TAGLN -0.35 -4.87 -0.4 3.27e-6 Blood protein levels; TGCT cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg11494091 chr17:61959527 GH2 0.52 11.94 0.73 2.4e-22 Prudent dietary pattern; TGCT cis rs2594989 0.691 rs2596816 chr3:11581200 A/C cg00170343 chr3:11313890 ATG7 0.67 5.18 0.42 8.69e-7 Circulating chemerin levels; TGCT cis rs11190604 0.806 rs11190510 chr10:102157175 G/A cg16342193 chr10:102329863 NA -0.39 -5.06 -0.41 1.49e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs875971 0.508 rs10258739 chr7:66062935 A/T cg00343986 chr7:65444356 GUSB -0.2 -4.54 -0.38 1.3e-5 Aortic root size; TGCT cis rs589249 0.963 rs4147222 chr1:37176422 G/A cg04012535 chr1:37176647 NA 0.33 5.39 0.44 3.46e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs9296092 0.560 rs9469505 chr6:33527348 A/G cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs3741151 1.000 rs76570090 chr11:73066321 A/T cg17517138 chr11:73019481 ARHGEF17 0.91 4.63 0.38 9e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs7020830 0.931 rs13295115 chr9:37157964 T/G cg14294708 chr9:37120828 ZCCHC7 1.3 18.09 0.85 1.38e-36 Schizophrenia; TGCT cis rs4776059 1.000 rs10851521 chr15:52942111 G/A cg25063058 chr15:52860530 ARPP19 0.51 4.57 0.38 1.18e-5 Schizophrenia; TGCT cis rs806215 0.547 rs3757778 chr7:127456607 C/T cg11539674 chr7:127291444 SND1 -0.36 -4.67 -0.39 7.77e-6 Type 2 diabetes; TGCT cis rs9291683 0.566 rs13122689 chr4:10044648 A/G cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Bone mineral density; TGCT cis rs2836950 0.501 rs4818018 chr21:40694072 C/T cg11890956 chr21:40555474 PSMG1 -0.66 -6.23 -0.49 6.75e-9 Menarche (age at onset); TGCT cis rs4665809 1.000 rs4665306 chr2:26319124 C/T cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs6671200 0.573 rs3738171 chr1:95699594 A/G cg20701556 chr1:95698924 RWDD3 -0.54 -5.31 -0.43 4.83e-7 Stearic acid (18:0) levels; TGCT trans rs564343 0.563 rs570760 chr11:65833631 C/T cg26701943 chr11:108369231 KDELC2 -0.73 -6.91 -0.53 2.21e-10 Obesity (early onset extreme); TGCT cis rs875971 1.000 rs4718307 chr7:65610988 A/G cg18876405 chr7:65276391 NA -0.32 -4.92 -0.4 2.69e-6 Aortic root size; TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg03724423 chr7:27170755 HOXA4 -0.43 -4.59 -0.38 1.05e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs425277 1.000 rs421992 chr1:2077260 C/T cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.13 0.63 1.6e-15 Cognitive function; TGCT cis rs10207060 0.500 rs6731870 chr2:240708096 C/A cg15726768 chr2:241314588 NA -0.32 -4.49 -0.37 1.63e-5 Obesity-related traits; TGCT cis rs9302001 1.000 rs9302001 chr13:95463392 A/G cg07483244 chr13:95358924 NA -0.38 -4.9 -0.4 2.97e-6 Panic disorder; TGCT cis rs9467711 0.606 rs16891725 chr6:26479150 C/T cg10795676 chr6:26370623 BTN3A2 -0.44 -4.72 -0.39 6.29e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs910187 0.678 rs6066231 chr20:45818895 C/T cg27589058 chr20:45804311 EYA2 -0.35 -7.32 -0.55 2.76e-11 Migraine; TGCT cis rs9926296 0.643 rs12596429 chr16:89841374 T/C cg04287289 chr16:89883240 FANCA 0.66 6.55 0.51 1.36e-9 Vitiligo; TGCT cis rs7394190 0.748 rs4746147 chr10:75527708 A/G cg07699608 chr10:75541558 CHCHD1 0.8 5.21 0.42 7.72e-7 Incident atrial fibrillation; TGCT cis rs763014 0.898 rs1981484 chr16:630710 A/G cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs3803170 0.513 rs10849943 chr12:111819589 A/G cg10833066 chr12:111807467 FAM109A -0.36 -5.66 -0.45 9.9e-8 Mean corpuscular hemoglobin; TGCT cis rs5769707 0.967 rs2187891 chr22:49994094 C/T cg05373962 chr22:49881684 NA -0.29 -6.04 -0.48 1.63e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7829975 0.545 rs13261926 chr8:8551610 T/C cg17143192 chr8:8559678 CLDN23 -0.46 -4.46 -0.37 1.79e-5 Mood instability; TGCT cis rs6121246 0.609 rs6060652 chr20:30266845 A/G cg10886678 chr20:30946050 ASXL1 -0.52 -4.44 -0.37 1.97e-5 Mean corpuscular hemoglobin; TGCT cis rs2963155 0.518 rs6196 chr5:142661490 A/G cg17617527 chr5:142782415 NR3C1 0.86 6.46 0.5 2.2e-9 Breast cancer; TGCT cis rs7666738 0.830 rs62321564 chr4:98976496 C/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg10819733 chr22:24237672 NA -0.3 -5.02 -0.41 1.77e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7394190 0.748 rs12572278 chr10:75504513 C/A cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.44e-6 Incident atrial fibrillation; TGCT cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs568617 1.000 rs693824 chr11:65654783 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.57 5.22 0.42 7.39e-7 Crohn's disease; TGCT cis rs12681287 0.547 rs13249177 chr8:87513034 A/G cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs3540 0.553 rs8042861 chr15:90977333 G/T cg22089800 chr15:90895588 ZNF774 0.74 7.82 0.57 2.01e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg01577475 chr2:114033581 PAX8;LOC440839 -0.44 -4.75 -0.39 5.42e-6 Lymphocyte counts; TGCT cis rs763121 0.853 rs5750622 chr22:38956464 C/G cg06022373 chr22:39101656 GTPBP1 0.8 7.79 0.57 2.29e-12 Menopause (age at onset); TGCT cis rs909002 0.849 rs10914453 chr1:32075036 A/G cg11573219 chr1:32083031 HCRTR1 -0.49 -6.41 -0.5 2.73e-9 Intelligence (multi-trait analysis); TGCT cis rs13326165 0.715 rs11709658 chr3:52399627 G/A cg27565382 chr3:53032988 SFMBT1 0.36 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs17001868 0.568 rs9611328 chr22:40791972 C/T cg07138101 chr22:40742427 ADSL 0.73 5.47 0.44 2.38e-7 Mammographic density (dense area); TGCT cis rs72949976 0.934 rs1922794 chr2:214026181 G/A cg08319019 chr2:214017104 IKZF2 -0.81 -7.57 -0.56 7.36e-12 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs68170813 0.652 rs12533694 chr7:107102817 C/T cg02696742 chr7:106810147 HBP1 -0.62 -4.63 -0.38 9.11e-6 Coronary artery disease; TGCT cis rs919433 0.679 rs6708239 chr2:198525084 A/G cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs240764 0.658 rs11155618 chr6:101181811 C/T cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs7264396 0.790 rs6121020 chr20:34252006 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs804280 0.662 rs810738 chr8:11611206 A/G cg26752888 chr8:11627280 NEIL2 -0.68 -5.34 -0.43 4.21e-7 Myopia (pathological); TGCT cis rs459571 0.959 rs410876 chr9:136893867 C/A cg13789015 chr9:136890014 NCRNA00094 0.41 7.73 0.57 3.24e-12 Platelet distribution width; TGCT cis rs73198271 0.740 rs10112989 chr8:8647334 A/C cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1670533 1.000 rs2045066 chr4:1052401 C/T cg27284194 chr4:1044797 NA 0.7 6.1 0.48 1.25e-8 Recombination rate (females); TGCT cis rs350251 0.837 rs1641850 chr16:12188433 C/G cg02910054 chr16:12241554 SNX29 0.33 4.46 0.37 1.85e-5 Intelligence (multi-trait analysis); TGCT cis rs2933343 0.679 rs789254 chr3:128574593 A/G cg11901034 chr3:128598214 ACAD9 -0.6 -5.58 -0.45 1.45e-7 IgG glycosylation; TGCT cis rs933688 1.000 rs186717 chr5:90780467 T/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.95 8.92 0.63 5.13e-15 Smoking behavior; TGCT cis rs929354 0.566 rs6979947 chr7:157005863 C/T cg05182265 chr7:156933206 UBE3C 0.35 7.05 0.54 1.08e-10 Body mass index; TGCT cis rs3764628 1.000 rs3752218 chr19:18761213 C/T cg20098710 chr19:19640075 YJEFN3 -0.44 -4.64 -0.38 8.89e-6 Orofacial clefts; TGCT cis rs4689592 0.583 rs6823154 chr4:7078145 C/T cg02503808 chr4:7069936 GRPEL1 0.9 8.26 0.6 1.86e-13 Monocyte percentage of white cells; TGCT cis rs7975161 0.882 rs4964270 chr12:104652398 A/G cg25273343 chr12:104657179 TXNRD1 -0.36 -5.28 -0.43 5.53e-7 Toenail selenium levels; TGCT cis rs12908161 1.000 rs12905057 chr15:85210765 A/G cg11189052 chr15:85197271 WDR73 0.77 6.28 0.49 5.27e-9 Schizophrenia; TGCT cis rs11030122 0.702 rs4910868 chr11:3980224 A/C cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs8064299 0.655 rs12797 chr17:72766993 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.61 5.59 0.45 1.35e-7 Monocyte count; TGCT cis rs6089829 0.962 rs6122344 chr20:61661738 C/T cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs6504663 0.596 rs7208018 chr17:48557863 C/T cg03168497 chr17:48586147 MYCBPAP -0.45 -5.18 -0.42 8.67e-7 Visceral fat; TGCT cis rs13256369 0.756 rs13282580 chr8:8562903 C/T cg17143192 chr8:8559678 CLDN23 0.56 5.31 0.43 4.9e-7 Obesity-related traits; TGCT cis rs921968 0.643 rs2556385 chr2:219532905 G/A cg02176678 chr2:219576539 TTLL4 -0.38 -5.47 -0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs72901758 0.662 rs56326958 chr17:76250439 C/G cg25512537 chr17:76250053 NA 0.25 4.51 0.38 1.49e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT trans rs4824093 0.610 rs13340054 chr22:50311726 G/A cg09872104 chr7:134855509 C7orf49 -0.93 -6.91 -0.53 2.29e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9916302 0.904 rs11078915 chr17:37715426 T/C cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs597539 0.652 rs686877 chr11:68637169 G/A cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2486288 0.656 rs10519018 chr15:45549265 C/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.33 -0.55 2.57e-11 Glomerular filtration rate; TGCT cis rs2153535 0.580 rs9505454 chr6:8478532 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs904251 0.523 rs9349039 chr6:37480392 A/G cg01843034 chr6:37503916 NA -0.55 -7.01 -0.53 1.36e-10 Cognitive performance; TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg09737314 chr17:6899359 ALOX12 0.48 5.27 0.43 5.84e-7 Tonsillectomy; TGCT cis rs28735056 0.935 rs537962 chr18:77592660 C/G cg20368463 chr18:77673604 PQLC1 0.46 5.67 0.45 9.72e-8 Schizophrenia; TGCT cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs727479 0.502 rs12591172 chr15:51503727 G/A cg19946085 chr15:51559439 CYP19A1 -0.31 -4.53 -0.38 1.39e-5 Estradiol levels; TGCT cis rs7666738 0.830 rs7687958 chr4:99014495 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11105298 0.891 rs10858896 chr12:89920184 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9467773 1.000 rs6933176 chr6:26540178 G/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg06481639 chr22:41940642 POLR3H -0.73 -6.49 -0.5 1.83e-9 Vitiligo; TGCT cis rs35306767 0.807 rs34527494 chr10:935192 T/C cg20503657 chr10:835505 NA 0.8 11.88 0.73 3.41e-22 Eosinophil percentage of granulocytes; TGCT trans rs6040399 1.000 rs6040399 chr20:11157011 A/T cg11320084 chr1:185014181 RNF2 -0.35 -6.81 -0.52 3.83e-10 Response to citalopram treatment; TGCT cis rs1461503 0.900 rs3751047 chr11:122828439 G/A cg27398637 chr11:122830231 C11orf63 -0.41 -4.77 -0.39 5.14e-6 Menarche (age at onset); TGCT cis rs2404602 0.709 rs11072597 chr15:76763514 C/A cg22467129 chr15:76604101 ETFA 0.48 5.11 0.42 1.16e-6 Blood metabolite levels; TGCT cis rs4689388 0.926 rs4458523 chr4:6289986 G/T cg25554036 chr4:6271136 WFS1 -0.54 -7.54 -0.56 8.85e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7829975 0.902 rs777707 chr8:8584344 A/G cg06636001 chr8:8085503 FLJ10661 0.59 5.12 0.42 1.14e-6 Mood instability; TGCT cis rs7647973 1.000 rs9871024 chr3:49554241 T/C cg06212747 chr3:49208901 KLHDC8B -0.54 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs11105298 0.891 rs12228177 chr12:89862030 G/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.96 10.35 0.68 1.75e-18 Intelligence (multi-trait analysis); TGCT cis rs1541995 1.000 rs35336871 chr15:96357133 C/T cg00882281 chr15:96346592 NA 0.29 4.76 0.39 5.31e-6 Photic sneeze reflex; TGCT cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs8077577 0.895 rs62073607 chr17:18071338 A/G cg09161412 chr17:18057145 MYO15A -0.63 -5.21 -0.42 7.62e-7 Obesity-related traits; TGCT cis rs950027 0.620 rs1145077 chr15:45683795 A/C cg26924012 chr15:45694286 SPATA5L1 -0.8 -8.55 -0.61 3.95e-14 Response to fenofibrate (adiponectin levels); TGCT trans rs8073060 0.963 rs11080353 chr17:33871281 C/T cg19694781 chr19:47549865 TMEM160 0.42 7.69 0.57 3.98e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2820315 1.000 rs2459761 chr1:201808469 C/G cg12730843 chr1:201915899 LMOD1 -0.26 -4.73 -0.39 6.01e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs644799 0.509 rs580181 chr11:95643040 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.48 5.0 0.41 1.87e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs873917 0.577 rs784612 chr1:40122939 T/C cg06209491 chr1:40138402 NT5C1A -0.35 -5.84 -0.46 4.21e-8 Amyotrophic lateral sclerosis; TGCT cis rs981844 0.885 rs72731673 chr4:154667446 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs57590327 0.503 rs11706976 chr3:81899653 C/T cg07356753 chr3:81810745 GBE1 -0.7 -6.42 -0.5 2.68e-9 Extraversion; TGCT cis rs2521263 1.000 rs2074018 chr11:2309634 A/T cg10151367 chr11:2847642 KCNQ1 0.48 4.61 0.38 9.75e-6 Obesity-related traits; TGCT cis rs9674544 0.740 rs11870560 chr17:47114033 T/C cg10950924 chr17:47092072 IGF2BP1 -0.35 -4.51 -0.38 1.51e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs6940638 0.688 rs1028308 chr6:27129757 G/A cg26531700 chr6:26746687 NA -0.53 -4.57 -0.38 1.15e-5 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg02487422 chr3:49467188 NICN1 0.55 5.32 0.43 4.77e-7 Menarche (age at onset); TGCT cis rs7909074 0.832 rs10793564 chr10:45386352 C/A cg05187965 chr10:45406764 TMEM72 -0.26 -5.42 -0.44 2.96e-7 Mean corpuscular volume; TGCT cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1862618 0.671 rs2591956 chr5:56244604 G/A cg12311346 chr5:56204834 C5orf35 0.57 6.09 0.48 1.28e-8 Initial pursuit acceleration; TGCT cis rs2688608 0.905 rs2633300 chr10:75656647 A/C cg23231163 chr10:75533350 FUT11 -0.25 -4.45 -0.37 1.89e-5 Inflammatory bowel disease; TGCT cis rs611744 0.523 rs13253581 chr8:109343105 A/G cg21045802 chr8:109455806 TTC35 0.83 9.03 0.63 2.75e-15 Dupuytren's disease; TGCT cis rs7916697 0.891 rs7897809 chr10:70000293 A/G cg18338521 chr10:69995036 NA -0.28 -4.47 -0.37 1.75e-5 Optic disc area; TGCT cis rs4460629 0.742 rs6427158 chr1:155074903 G/T cg23973274 chr1:155060172 NA -0.26 -4.66 -0.39 8.1e-6 Serum magnesium levels; TGCT cis rs9583531 0.600 rs7986286 chr13:111357207 A/G cg24331049 chr13:111365604 ING1 0.77 7.44 0.56 1.45e-11 Coronary artery disease; TGCT cis rs6582630 0.502 rs11181230 chr12:38300085 A/G cg26384229 chr12:38710491 ALG10B 0.8 7.04 0.53 1.17e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs617219 0.659 rs13182512 chr5:78573790 A/T cg23514016 chr5:78407564 BHMT -0.32 -4.87 -0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs28493229 0.708 rs10408065 chr19:41161096 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs2692947 0.644 rs772175 chr2:96944553 G/A cg23100626 chr2:96804247 ASTL 0.45 5.73 0.46 7.26e-8 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2180341 0.538 rs3756993 chr6:127651551 A/C cg27446573 chr6:127587934 RNF146 0.66 5.86 0.47 3.96e-8 Breast cancer; TGCT cis rs3741151 1.000 rs1892855 chr11:73017972 G/T cg17517138 chr11:73019481 ARHGEF17 1.16 5.5 0.44 2.11e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs10927875 0.800 rs1627145 chr1:16328116 C/T cg21385522 chr1:16154831 NA 0.64 6.9 0.53 2.33e-10 Dilated cardiomyopathy; TGCT cis rs3820068 0.603 rs6695903 chr1:15985940 C/T cg05660106 chr1:15850417 CASP9 0.84 8.69 0.62 1.82e-14 Systolic blood pressure; TGCT cis rs9611519 0.780 rs2284079 chr22:41658632 C/T cg13695892 chr22:41940480 POLR3H -0.64 -6.04 -0.48 1.62e-8 Neuroticism; TGCT cis rs1008375 0.966 rs3796813 chr4:17591648 A/G cg18681998 chr4:17616180 MED28 0.96 9.84 0.66 3.1e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9393692 0.875 rs9393690 chr6:26271713 A/T cg00631329 chr6:26305371 NA -0.43 -6.41 -0.5 2.72e-9 Educational attainment; TGCT cis rs801193 0.935 rs2286683 chr7:66129843 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.13 -0.42 1.07e-6 Aortic root size; TGCT cis rs1577917 0.917 rs12665464 chr6:86574133 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.47 -0.44 2.33e-7 Response to antipsychotic treatment; TGCT cis rs2836633 0.929 rs62217519 chr21:40034390 G/A cg12884169 chr21:40033163 ERG 0.43 4.57 0.38 1.16e-5 Coronary artery disease; TGCT cis rs11648796 0.759 rs12597195 chr16:769026 G/C cg07343612 chr16:622815 PIGQ -0.38 -5.28 -0.43 5.53e-7 Height; TGCT cis rs1691799 0.899 rs1168321 chr12:66744517 C/G cg16791601 chr12:66731901 HELB 0.28 6.17 0.48 8.87e-9 White blood cell count (basophil); TGCT cis rs8010715 1.000 rs3742500 chr14:24611978 G/T cg23112188 chr14:24563095 PCK2 -0.41 -4.94 -0.41 2.49e-6 IgG glycosylation; TGCT cis rs707040 0.921 rs2348925 chr2:155229374 T/C cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs12971120 0.891 rs12968731 chr18:72169708 G/T cg25817165 chr18:72167213 CNDP2 -0.29 -5.11 -0.42 1.16e-6 Refractive error; TGCT cis rs9911578 0.900 rs7214335 chr17:57158840 G/A cg12560992 chr17:57184187 TRIM37 0.8 9.86 0.66 2.69e-17 Intelligence (multi-trait analysis); TGCT cis rs60871478 0.947 rs4074610 chr7:791755 G/A cg05535760 chr7:792225 HEATR2 0.33 4.57 0.38 1.15e-5 Cerebrospinal P-tau181p levels; TGCT cis rs11112613 0.775 rs12305225 chr12:105963266 G/C cg03607813 chr12:105948248 NA 0.44 5.31 0.43 4.89e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg07636037 chr3:49044803 WDR6 0.95 10.21 0.68 3.98e-18 Parkinson's disease; TGCT cis rs2354432 0.607 rs59689207 chr1:146722484 G/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs2204008 0.543 rs2387018 chr12:38065638 C/T cg26384229 chr12:38710491 ALG10B 0.87 7.79 0.57 2.32e-12 Bladder cancer; TGCT cis rs921968 0.643 rs579610 chr2:219327582 C/A cg02176678 chr2:219576539 TTLL4 0.43 6.29 0.49 5.03e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs9952991 0.941 rs9952749 chr18:12780456 A/G cg23544223 chr18:12777786 NA 0.63 6.02 0.48 1.85e-8 Inflammatory skin disease; TGCT cis rs59197085 0.551 rs60384027 chr7:128437514 G/A cg00260937 chr7:128520193 KCP 0.45 4.66 0.39 7.95e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg08859206 chr1:53392774 SCP2 -0.42 -6.23 -0.49 6.54e-9 Monocyte count; TGCT cis rs6500602 0.561 rs62039231 chr16:4519548 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.69 0.45 8.69e-8 Schizophrenia; TGCT cis rs6547741 0.743 rs7564625 chr2:27862397 C/T cg27432699 chr2:27873401 GPN1 -0.24 -6.05 -0.48 1.57e-8 Oral cavity cancer; TGCT cis rs11096990 0.634 rs12651217 chr4:39273584 C/T cg20847110 chr4:39482781 LOC401127 0.16 4.53 0.38 1.38e-5 Cognitive function; TGCT cis rs2806561 0.704 rs856510 chr1:23524407 A/C cg12483005 chr1:23474871 LUZP1 0.42 5.41 0.44 3.15e-7 Height; TGCT cis rs11167764 0.945 rs891991 chr5:141484977 A/T cg08523384 chr5:141488047 NDFIP1 -0.26 -5.41 -0.44 3.08e-7 Crohn's disease; TGCT cis rs72781680 0.898 rs12619592 chr2:23971415 C/A cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs4689388 0.824 rs114669221 chr4:6301459 G/A cg14416269 chr4:6271139 WFS1 0.37 4.8 0.4 4.4e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs910316 0.763 rs175057 chr14:75489632 C/T cg11812906 chr14:75593930 NEK9 -0.56 -5.3 -0.43 5.11e-7 Height; TGCT cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg08280861 chr8:58055591 NA 0.51 5.73 0.46 7.17e-8 Developmental language disorder (linguistic errors); TGCT cis rs7216064 1.000 rs12451707 chr17:65871598 G/A cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4699052 0.787 rs2169508 chr4:104066890 T/A cg16532752 chr4:104119610 CENPE -0.6 -5.47 -0.44 2.34e-7 Testicular germ cell tumor; TGCT cis rs67478160 0.619 rs1187416 chr14:104311465 A/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg23131131 chr22:24373011 LOC391322 -0.81 -8.79 -0.62 1.03e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9921192 0.967 rs251735 chr16:4320672 G/C cg00021532 chr16:4324280 TFAP4 0.83 9.42 0.65 3.22e-16 Prostate-specific antigen levels; TGCT cis rs909002 0.772 rs10914452 chr1:32074575 G/A cg11573219 chr1:32083031 HCRTR1 -0.45 -5.87 -0.47 3.67e-8 Intelligence (multi-trait analysis); TGCT cis rs7769051 1.000 rs73554431 chr6:133129922 T/G cg07930552 chr6:133119739 C6orf192 0.94 5.09 0.42 1.28e-6 Type 2 diabetes nephropathy; TGCT cis rs4851266 1.000 rs1465801 chr2:100836060 C/T cg07810366 chr2:100720526 AFF3 -0.38 -5.48 -0.44 2.24e-7 Educational attainment; TGCT cis rs7726839 0.561 rs4957049 chr5:579080 C/A cg09021430 chr5:549028 NA -0.37 -5.39 -0.44 3.37e-7 Obesity-related traits; TGCT cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg00149659 chr3:10157352 C3orf10 0.96 6.13 0.48 1.1e-8 Alzheimer's disease; TGCT cis rs59698941 0.550 rs60042615 chr5:132193220 A/G cg27099455 chr5:132201840 GDF9;UQCRQ 0.3 4.94 0.41 2.44e-6 Apolipoprotein A-IV levels; TGCT cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg25767906 chr1:53392781 SCP2 0.47 5.26 0.43 6.03e-7 Monocyte count; TGCT cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg07424592 chr7:64974309 NA 1.26 7.55 0.56 7.99e-12 Diabetic kidney disease; TGCT cis rs56399783 0.901 rs56356906 chr7:2774383 G/A cg19731401 chr7:2775893 GNA12 0.36 5.07 0.41 1.4e-6 Childhood ear infection; TGCT cis rs172166 0.561 rs149971 chr6:27982152 G/A cg11262757 chr6:27280423 POM121L2 0.5 4.81 0.4 4.25e-6 Cardiac Troponin-T levels; TGCT cis rs801193 0.904 rs4718403 chr7:66242729 C/G cg00343986 chr7:65444356 GUSB 0.23 5.13 0.42 1.08e-6 Aortic root size; TGCT cis rs1008375 0.931 rs6449310 chr4:17575530 T/C cg18681998 chr4:17616180 MED28 0.93 9.3 0.64 6.29e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs72781680 1.000 rs72796389 chr2:24171761 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs56235845 0.694 rs11949401 chr5:176765989 A/G cg16006841 chr5:176797999 RGS14 0.5 7.45 0.56 1.38e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg06753367 chr22:24256600 NA -0.24 -4.59 -0.38 1.05e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7824557 0.505 rs2572440 chr8:11249010 G/T cg21775007 chr8:11205619 TDH 0.66 6.92 0.53 2.1e-10 Retinal vascular caliber; TGCT cis rs2153535 0.580 rs9393019 chr6:8462091 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7267979 1.000 rs2500436 chr20:25406366 G/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg11644478 chr21:40555479 PSMG1 0.64 5.74 0.46 6.99e-8 Cognitive function; TGCT cis rs3784262 0.669 rs12594082 chr15:58267779 G/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.94 -0.47 2.7e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs950169 1.000 rs12915234 chr15:84758301 G/A cg17173187 chr15:85201210 NMB 0.48 5.39 0.44 3.36e-7 Schizophrenia; TGCT cis rs11030122 0.660 rs10160753 chr11:3894712 T/G cg18678763 chr11:4115507 RRM1 -0.35 -4.47 -0.37 1.71e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs6882046 0.513 rs601942 chr5:88031820 T/C cg22951263 chr5:87985283 NA -0.55 -5.94 -0.47 2.74e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs7772486 0.558 rs9497403 chr6:146054695 T/G cg13319975 chr6:146136371 FBXO30 0.74 6.68 0.51 7.36e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4727027 0.704 rs13229244 chr7:148898219 A/C cg23583168 chr7:148888333 NA 0.78 10.81 0.7 1.32e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7659604 0.540 rs28394772 chr4:122678543 C/T cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.92e-6 Type 2 diabetes; TGCT cis rs112591243 0.570 rs17302700 chr21:47969793 C/T cg10657630 chr21:48055338 PRMT2 1.03 4.63 0.38 9.08e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1801251 1.000 rs2592105 chr2:233645968 C/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs4665809 1.000 rs4665820 chr2:26309150 T/C cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs909002 0.925 rs4949455 chr1:32114793 C/T cg11573219 chr1:32083031 HCRTR1 -0.45 -5.79 -0.46 5.44e-8 Intelligence (multi-trait analysis); TGCT cis rs7119038 0.509 rs10790261 chr11:118579747 C/T cg19308663 chr11:118741387 NA -0.26 -4.58 -0.38 1.14e-5 Sjögren's syndrome; TGCT cis rs35160687 0.901 rs12714179 chr2:86514958 T/C cg03171300 chr2:86307199 POLR1A 0.32 5.54 0.45 1.73e-7 Night sleep phenotypes; TGCT cis rs3806843 0.676 rs778591 chr5:140025484 G/A cg19875535 chr5:140030758 IK -0.35 -6.07 -0.48 1.46e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs1878931 0.543 rs17612463 chr16:3420479 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 6.35 0.5 3.66e-9 Body mass index (adult); TGCT cis rs9549367 0.673 rs575453 chr13:113837871 C/A cg00898013 chr13:113819073 PROZ 0.53 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs1372520 0.684 rs2197120 chr4:90729602 A/G cg20003494 chr4:90757398 SNCA -0.66 -5.21 -0.42 7.59e-7 Neuroticism; TGCT cis rs4788570 0.578 rs9934789 chr16:71662467 A/G cg06353428 chr16:71660113 MARVELD3 1.56 12.61 0.75 5.63e-24 Intelligence (multi-trait analysis); TGCT cis rs797680 0.856 rs10874762 chr1:93639101 T/G cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.93e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9611519 0.929 rs9611509 chr22:41565827 A/G cg03806693 chr22:41940476 POLR3H -0.67 -6.19 -0.49 7.94e-9 Neuroticism; TGCT cis rs1843834 1.000 rs4624372 chr2:225553128 A/G cg22455342 chr2:225449267 CUL3 0.75 7.37 0.55 2.15e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs7666738 0.606 rs28625338 chr4:99076996 A/G cg17366294 chr4:99064904 C4orf37 0.58 5.46 0.44 2.55e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12926788 0.546 rs200531 chr16:24756172 G/A cg06028605 chr16:24865363 SLC5A11 -0.42 -4.69 -0.39 7.14e-6 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg23283495 chr1:209979779 IRF6 0.65 5.53 0.44 1.81e-7 Cleft lip with or without cleft palate; TGCT cis rs8084125 0.832 rs62105179 chr18:74950858 A/G cg15443732 chr18:74961078 GALR1 0.48 4.7 0.39 6.76e-6 Obesity-related traits; TGCT cis rs185538822 1 rs185538822 chr4:106803682 A/C cg24545054 chr4:106630052 GSTCD;INTS12 1.01 4.61 0.38 9.71e-6 Post bronchodilator FEV1; TGCT cis rs11098499 0.754 rs28643450 chr4:120245242 G/A cg09307838 chr4:120376055 NA 0.6 5.65 0.45 1.02e-7 Corneal astigmatism; TGCT cis rs7666738 0.830 rs10022331 chr4:98960392 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9372253 0.678 rs9487392 chr6:110708626 C/T cg13266496 chr6:110720918 DDO 0.39 4.52 0.38 1.41e-5 Platelet distribution width; TGCT cis rs11031096 0.542 rs6578424 chr11:3973140 G/A cg18678763 chr11:4115507 RRM1 -0.42 -5.14 -0.42 1.05e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1994135 0.692 rs1816958 chr12:33695066 A/T cg06521331 chr12:34319734 NA -0.3 -4.69 -0.39 6.97e-6 Resting heart rate; TGCT cis rs3820928 0.874 rs6718057 chr2:227834349 T/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs6540559 0.546 rs75308488 chr1:210030639 T/C cg23283495 chr1:209979779 IRF6 0.66 4.95 0.41 2.37e-6 Cleft lip with or without cleft palate; TGCT cis rs1949733 0.848 rs2255501 chr4:8475014 G/A cg13073564 chr4:8508604 NA 0.44 4.65 0.39 8.24e-6 Response to antineoplastic agents; TGCT cis rs6831352 0.589 rs2924584 chr4:99988208 A/G cg12011299 chr4:100065546 ADH4 0.38 5.47 0.44 2.4e-7 Alcohol dependence; TGCT cis rs10875595 0.836 rs59933130 chr5:140667303 G/A cg24830062 chr5:140700576 TAF7 -0.6 -5.13 -0.42 1.09e-6 Pulmonary function decline; TGCT cis rs61774743 0.636 rs1892423 chr1:41849340 A/C cg01193554 chr1:41846683 NA -0.44 -5.49 -0.44 2.13e-7 Intelligence (multi-trait analysis); TGCT cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg05368731 chr17:41323189 NBR1 1.16 13.76 0.78 1.03e-26 Menopause (age at onset); TGCT cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg03161606 chr19:29218774 NA 0.6 5.84 0.46 4.28e-8 Methadone dose in opioid dependence; TGCT cis rs12681287 0.640 rs12678720 chr8:87457929 T/G cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg23758822 chr17:41437982 NA 0.69 6.56 0.51 1.33e-9 Menopause (age at onset); TGCT cis rs8013055 0.796 rs8005568 chr14:105971794 A/G cg23356831 chr14:105996513 TMEM121 0.38 5.91 0.47 3.1e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs33794 0.901 rs33776 chr3:45286898 C/T cg18645101 chr3:44551900 NA 0.55 4.82 0.4 4.08e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs244731 0.959 rs6556307 chr5:176641434 C/T cg17509989 chr5:176798049 RGS14 0.61 7.3 0.55 2.98e-11 Urate levels in lean individuals; TGCT cis rs9549367 0.673 rs575453 chr13:113837871 C/A cg09473364 chr13:112927190 NA 0.29 4.64 0.38 8.73e-6 Platelet distribution width; TGCT cis rs7914558 0.966 rs10748839 chr10:104953547 A/G cg05855489 chr10:104503620 C10orf26 0.52 4.58 0.38 1.1e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3772130 0.962 rs6776670 chr3:121543120 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.5 4.49 0.37 1.63e-5 Cognitive performance; TGCT cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs57920188 0.584 rs57277002 chr1:4092054 T/G cg20703997 chr1:4087676 NA 0.49 5.79 0.46 5.39e-8 Interleukin-17 levels; TGCT cis rs7666738 0.830 rs9992639 chr4:98940400 G/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs9650657 0.515 rs6601560 chr8:10950866 T/C cg15556689 chr8:8085844 FLJ10661 -0.85 -8.3 -0.6 1.46e-13 Neuroticism; TGCT cis rs8014252 0.803 rs7157618 chr14:71010166 C/T cg11204974 chr14:71022665 NA -0.53 -4.46 -0.37 1.79e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs992157 0.775 rs7559428 chr2:219150238 A/G cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT cis rs11264213 0.901 rs649152 chr1:36438649 T/G cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs9467773 0.967 rs1056347 chr6:26527524 G/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs2594989 0.943 rs2454493 chr3:11506458 A/G cg26283222 chr3:11613257 VGLL4 -0.22 -4.65 -0.39 8.53e-6 Circulating chemerin levels; TGCT cis rs6424115 0.867 rs2501432 chr1:24201920 T/C cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs9972944 0.756 rs6504357 chr17:63770621 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs2288884 0.943 rs11084131 chr19:52514446 G/A cg15405931 chr19:52693188 PPP2R1A -0.69 -4.47 -0.37 1.77e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs274567 0.550 rs272885 chr5:131667736 A/G cg24060327 chr5:131705240 SLC22A5 -0.76 -8.4 -0.6 8.54e-14 Blood metabolite levels; TGCT cis rs17102423 0.594 rs4902360 chr14:65546722 A/C cg11161011 chr14:65562177 MAX -0.46 -6.47 -0.5 2.04e-9 Obesity-related traits; TGCT cis rs9393692 0.875 rs2142703 chr6:26289605 A/G cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.14e-9 Educational attainment; TGCT cis rs4819052 0.918 rs34886433 chr21:46680538 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.89 6.51 0.5 1.66e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7582180 0.629 rs13031508 chr2:100952757 A/G cg14675211 chr2:100938903 LONRF2 0.5 4.76 0.39 5.35e-6 Intelligence (multi-trait analysis); TGCT cis rs1971762 0.762 rs4759282 chr12:54072435 C/A cg16917193 chr12:54089295 NA 0.6 4.79 0.4 4.69e-6 Height; TGCT cis rs137603 0.502 rs137627 chr22:39716341 G/A cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.8 -0.4 4.49e-6 Primary biliary cholangitis; TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg10263370 chr3:44754102 ZNF502 -0.46 -5.56 -0.45 1.61e-7 Depressive symptoms; TGCT cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg27535305 chr1:53392650 SCP2 -0.24 -4.69 -0.39 6.96e-6 Monocyte count; TGCT cis rs41271951 0.512 rs12090246 chr1:151107496 G/A cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs78456975 0.506 rs10206900 chr2:1552841 T/C cg01028140 chr2:1542097 TPO -0.34 -4.86 -0.4 3.54e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7666738 0.830 rs1426666 chr4:99030887 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg20818283 chr2:191399100 TMEM194B 0.48 4.52 0.38 1.44e-5 Pulse pressure; TGCT cis rs2180341 0.596 rs12215298 chr6:127676833 C/T cg27446573 chr6:127587934 RNF146 0.76 6.71 0.52 6.24e-10 Breast cancer; TGCT cis rs9549367 0.789 rs9549699 chr13:113878263 T/A cg18105134 chr13:113819100 PROZ -0.33 -5.38 -0.43 3.61e-7 Platelet distribution width; TGCT cis rs13191362 0.938 rs13208970 chr6:163006368 G/T cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2404602 0.692 rs55729975 chr15:76803226 G/A cg22467129 chr15:76604101 ETFA -0.48 -5.56 -0.45 1.58e-7 Blood metabolite levels; TGCT trans rs10022799 0.725 rs10002479 chr4:168136279 A/G cg08507725 chr4:8239220 SH3TC1 -0.4 -7.28 -0.55 3.31e-11 Cognitive function; TGCT cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg10802521 chr3:52805072 NEK4 -0.73 -9.41 -0.65 3.43e-16 Bipolar disorder; TGCT cis rs10193935 0.901 rs6544533 chr2:42516372 G/C cg27598129 chr2:42591480 NA -0.33 -4.7 -0.39 6.93e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs1062177 1.000 rs973529 chr5:151188158 T/C cg12924095 chr5:151150029 G3BP1 0.35 4.94 0.41 2.52e-6 Preschool internalizing problems; TGCT cis rs7617773 0.780 rs11130164 chr3:48369034 G/A cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs2456568 0.802 rs8181578 chr11:93637442 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10875595 0.836 rs3749780 chr5:140682757 C/T cg24830062 chr5:140700576 TAF7 -0.64 -5.37 -0.43 3.7e-7 Pulmonary function decline; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg01585852 chr22:24235823 MIF -0.21 -4.56 -0.38 1.23e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6964587 0.933 rs13230837 chr7:91779017 A/G cg17063962 chr7:91808500 NA 0.92 9.89 0.66 2.4e-17 Breast cancer; TGCT cis rs6840360 0.571 rs1822347 chr4:152525319 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs4689388 0.890 rs3821941 chr4:6286954 A/G cg25554036 chr4:6271136 WFS1 0.57 8.16 0.59 3.18e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs603424 0.597 rs574122 chr10:102089174 C/A cg00409684 chr10:102984527 NA 0.61 4.69 0.39 7.04e-6 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs11578119 1.000 rs12138428 chr1:170505188 T/G cg09767346 chr1:170501363 GORAB 0.65 5.17 0.42 9.21e-7 Male-pattern baldness; TGCT cis rs4776059 1.000 rs4776059 chr15:52886962 C/T cg25063058 chr15:52860530 ARPP19 0.53 4.79 0.4 4.59e-6 Schizophrenia; TGCT cis rs4517514 0.509 rs11018869 chr11:89865168 A/G cg05041596 chr11:89867385 NAALAD2 0.52 4.56 0.38 1.22e-5 Trans fatty acid levels; TGCT cis rs892961 0.931 rs2411110 chr17:75400143 A/C cg05865280 chr17:75406074 SEPT9 0.28 5.81 0.46 4.95e-8 Airflow obstruction; TGCT cis rs910316 0.870 rs7147712 chr14:75670707 C/G cg11812906 chr14:75593930 NEK9 -0.68 -6.9 -0.53 2.39e-10 Height; TGCT cis rs7089973 0.604 rs1359079 chr10:116582502 A/G cg03647239 chr10:116582469 FAM160B1 0.58 5.63 0.45 1.16e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs11148252 0.904 rs9536079 chr13:53030565 G/A cg00495681 chr13:53174319 NA 0.6 6.32 0.49 4.23e-9 Lewy body disease; TGCT cis rs796364 0.789 rs176008 chr2:200814720 A/T cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs6484504 0.576 rs169623 chr11:31184157 T/C cg26647111 chr11:31128758 NA -0.34 -4.63 -0.38 9.09e-6 Red blood cell count; TGCT cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg16414030 chr3:133502952 NA -0.52 -7.29 -0.55 3.17e-11 Iron status biomarkers; TGCT cis rs3617 0.573 rs4687680 chr3:52907372 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.84 -0.4 3.85e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs17221829 0.673 rs56004718 chr11:89413190 A/G cg02982614 chr11:89391479 FOLH1B -0.28 -4.66 -0.39 7.94e-6 Anxiety in major depressive disorder; TGCT cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg17971929 chr21:40555470 PSMG1 -0.9 -8.51 -0.61 4.66e-14 Cognitive function; TGCT cis rs2404602 0.583 rs12913096 chr15:76551852 C/T cg22467129 chr15:76604101 ETFA -0.61 -7.83 -0.58 1.89e-12 Blood metabolite levels; TGCT cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg25660036 chr4:7070649 GRPEL1 0.62 5.52 0.44 1.91e-7 Monocyte percentage of white cells; TGCT cis rs6684514 1.000 rs10908498 chr1:156278175 T/C cg16558208 chr1:156270281 VHLL 0.48 9.61 0.65 1.13e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs28595532 0.920 rs17325129 chr4:119778284 T/C cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs9443645 0.810 rs9443637 chr6:79714708 C/T cg09184832 chr6:79620586 NA -0.43 -4.83 -0.4 3.93e-6 Intelligence (multi-trait analysis); TGCT cis rs35883536 0.647 rs10493929 chr1:101043928 A/C cg10298815 chr1:101004474 GPR88 -0.26 -4.8 -0.4 4.47e-6 Monocyte count; TGCT cis rs12220898 0.749 rs7098191 chr10:50481213 A/G cg06072769 chr10:50146962 WDFY4 0.38 4.98 0.41 2.07e-6 Inflammatory biomarkers; TGCT cis rs12579753 0.917 rs10862375 chr12:82254809 C/G cg07988820 chr12:82153109 PPFIA2 0.5 5.29 0.43 5.43e-7 Resting heart rate; TGCT cis rs2456568 0.803 rs10765641 chr11:93640312 T/C cg14065697 chr11:93583672 C11orf90 -0.36 -4.45 -0.37 1.85e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6088580 0.634 rs2184836 chr20:32963369 A/G cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs919433 0.713 rs55642934 chr2:198491110 C/T cg00792783 chr2:198669748 PLCL1 0.49 4.51 0.38 1.46e-5 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs4713118 0.824 rs9366702 chr6:27734470 T/C cg02458000 chr6:26745757 NA -0.52 -4.49 -0.37 1.64e-5 Parkinson's disease; TGCT cis rs4713118 0.955 rs9380012 chr6:27684654 A/G cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg07061783 chr6:25882402 NA -0.58 -5.58 -0.45 1.46e-7 Intelligence (multi-trait analysis); TGCT cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg01765077 chr12:122356316 WDR66 0.32 4.64 0.38 8.82e-6 Mean corpuscular volume; TGCT cis rs7826238 0.535 rs2979179 chr8:8320029 C/T cg08975724 chr8:8085496 FLJ10661 0.59 5.42 0.44 2.96e-7 Systolic blood pressure; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg25767906 chr1:53392781 SCP2 -0.57 -6.63 -0.51 9.03e-10 Monocyte count; TGCT cis rs7100689 0.577 rs9421464 chr10:82043426 C/T cg01528321 chr10:82214614 TSPAN14 0.67 6.45 0.5 2.31e-9 Post bronchodilator FEV1; TGCT cis rs3125734 0.653 rs1007976 chr10:63970144 C/T cg19640130 chr10:64028056 RTKN2 0.41 5.24 0.43 6.58e-7 Rheumatoid arthritis; TGCT cis rs7940866 0.903 rs1433980 chr11:130870956 A/G cg05962950 chr11:130786565 SNX19 0.59 5.34 0.43 4.3e-7 Schizophrenia; TGCT cis rs1362404 0.653 rs1118081 chr16:51964912 C/T cg03955530 chr16:52681474 NA 0.3 4.62 0.38 9.63e-6 Gut microbiota (bacterial taxa); TGCT cis rs17718580 0.536 rs56285552 chr14:51044852 G/C cg04730355 chr14:51134070 SAV1 1.25 8.77 0.62 1.16e-14 Cognitive performance; TGCT cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg03351412 chr1:154909251 PMVK 0.52 4.8 0.4 4.51e-6 Prostate cancer; TGCT cis rs13064447 0.817 rs3732687 chr3:12776428 A/C cg20675869 chr3:12750130 NA -0.2 -5.01 -0.41 1.79e-6 Major depression and alcohol dependence; TGCT cis rs4372836 1.000 rs4666118 chr2:28951698 C/T cg09522027 chr2:28974177 PPP1CB -0.59 -5.11 -0.42 1.19e-6 Body mass index; TGCT cis rs709400 1.000 rs7150141 chr14:104129352 G/A cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs7937682 0.855 rs10891285 chr11:111527775 T/C cg09085632 chr11:111637200 PPP2R1B -1.1 -11.66 -0.72 1.13e-21 Primary sclerosing cholangitis; TGCT cis rs4478858 0.698 rs4949204 chr1:31800415 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg23758822 chr17:41437982 NA 0.72 6.91 0.53 2.23e-10 Menopause (age at onset); TGCT cis rs13242816 1.000 rs12668226 chr7:116187690 A/C cg16553024 chr7:116138462 CAV2 -0.45 -5.3 -0.43 5.1e-7 P wave duration; TGCT cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg10295955 chr4:187884368 NA -0.97 -14.67 -0.8 7e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg16414030 chr3:133502952 NA -0.68 -11.13 -0.71 2.23e-20 Iron status biomarkers; TGCT cis rs7429990 0.870 rs13089844 chr3:48140231 G/A cg11946769 chr3:48343235 NME6 -0.57 -4.77 -0.39 5.14e-6 Educational attainment (years of education); TGCT cis rs7772486 0.727 rs11155442 chr6:146140725 T/C cg05347473 chr6:146136440 FBXO30 0.55 5.16 0.42 9.53e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs35306767 0.953 rs35693858 chr10:979813 C/T cg20503657 chr10:835505 NA 0.6 8.41 0.6 8.02e-14 Eosinophil percentage of granulocytes; TGCT cis rs9660180 0.846 rs10907195 chr1:1713348 C/T cg17747265 chr1:1875780 NA 0.36 6.02 0.48 1.86e-8 Body mass index; TGCT cis rs6840360 0.642 rs4235219 chr4:152346103 T/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.41 -0.5 2.81e-9 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.649 rs2064189 chr22:42127999 A/G cg13695892 chr22:41940480 POLR3H 0.83 7.93 0.58 1.09e-12 Vitiligo; TGCT cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.57e-7 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs4272321 1 rs4272321 chr7:157951835 A/G cg20528787 chr7:158032352 PTPRN2 0.32 4.51 0.38 1.48e-5 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg16423285 chr20:60520624 NA -0.69 -7.45 -0.56 1.39e-11 Body mass index; TGCT cis rs9296661 0.680 rs12197299 chr6:51685513 C/T cg00593404 chr6:52377740 TRAM2 -0.26 -4.46 -0.37 1.81e-5 Weight loss (gastric bypass surgery); TGCT cis rs55883249 0.958 rs17362734 chr2:9730208 A/G cg23886495 chr2:9695866 ADAM17 0.77 4.69 0.39 7.19e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs425277 0.583 rs12059660 chr1:2041461 C/T cg03732007 chr1:2071316 PRKCZ -0.26 -5.88 -0.47 3.59e-8 Height; TGCT cis rs826838 1.000 rs1963562 chr12:38662896 C/T cg26384229 chr12:38710491 ALG10B 1.05 10.25 0.68 3.18e-18 Heart rate; TGCT cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs1057239 0.510 rs3766694 chr1:175143207 T/C cg08873628 chr1:175162347 KIAA0040 -0.66 -7.02 -0.53 1.27e-10 Diastolic blood pressure; TGCT cis rs3733585 0.682 rs13124563 chr4:9927553 A/G cg11266682 chr4:10021025 SLC2A9 0.58 7.38 0.55 2.04e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2147959 0.824 rs4653970 chr1:228690292 T/C cg22700015 chr1:228743131 NA -0.61 -4.61 -0.38 9.95e-6 Adult asthma; TGCT cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs769267 1.000 rs2285627 chr19:19467937 T/C cg03709012 chr19:19516395 GATAD2A -0.68 -5.78 -0.46 5.56e-8 Tonsillectomy; TGCT cis rs138249 0.505 rs138219 chr22:50548985 T/C cg24864161 chr22:50528282 MOV10L1 0.5 4.45 0.37 1.91e-5 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs11731606 0.508 rs9307140 chr4:95288670 G/C cg00507259 chr4:95128692 SMARCAD1 0.65 4.89 0.4 3.02e-6 Mean platelet volume; TGCT cis rs10206020 0.885 rs11885392 chr2:1578182 C/A cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs7213347 0.610 rs8077194 chr17:2119475 A/G cg20777128 chr17:1945076 DPH1;OVCA2 -0.59 -5.41 -0.44 3.14e-7 Total body bone mineral density; TGCT trans rs797680 0.754 rs12118230 chr1:93651461 T/G cg27528825 chr2:159282178 CCDC148 -0.35 -6.82 -0.52 3.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6121246 0.567 rs6060261 chr20:30192948 C/G cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT trans rs916888 0.610 rs199436 chr17:44789285 C/T cg10053473 chr17:62856997 LRRC37A3 0.4 7.11 0.54 8.09e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12142240 0.698 rs72886907 chr1:46814265 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.75 0.46 6.47e-8 Menopause (age at onset); TGCT cis rs12220238 1.000 rs7909664 chr10:75869754 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.94 0.58 1.02e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs61935443 1.000 rs4761691 chr12:95248171 C/G cg21533806 chr12:95267307 NA 0.52 4.55 0.38 1.26e-5 Schizophrenia; TGCT cis rs6906287 0.537 rs13192336 chr6:118875162 A/T cg21191810 chr6:118973309 C6orf204 0.26 4.5 0.38 1.51e-5 Electrocardiographic conduction measures; TGCT cis rs1577917 0.771 rs2758847 chr6:86349103 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs4713118 0.826 rs2893929 chr6:27738732 A/T cg20933634 chr6:27740509 NA 0.35 4.83 0.4 3.92e-6 Parkinson's disease; TGCT cis rs6901250 0.744 rs636872 chr6:117087944 C/T cg12892004 chr6:117198278 RFX6 0.51 6.25 0.49 6.07e-9 C-reactive protein levels; TGCT cis rs9787249 0.957 rs41267029 chr1:40214367 A/G cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs12615966 0.651 rs60920571 chr2:105408284 C/G cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs2456568 0.548 rs7117597 chr11:93655091 A/G cg26875233 chr11:93583750 C11orf90 -0.43 -5.36 -0.43 3.96e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs4733781 0.527 rs11774659 chr8:131190336 C/T cg16277922 chr8:131349729 ASAP1 0.35 4.87 0.4 3.33e-6 Tuberculosis; TGCT cis rs2639990 1.000 rs655156 chr18:72898181 T/C cg03972071 chr18:72917163 ZADH2 0.8 5.54 0.45 1.75e-7 Vascular endothelial growth factor levels; TGCT cis rs7714584 1.000 rs6875011 chr5:150182710 G/A cg22134413 chr5:150180641 NA 1.17 8.69 0.62 1.76e-14 Crohn's disease; TGCT cis rs35306767 0.761 rs12770910 chr10:1050318 A/G cg18964960 chr10:1102726 WDR37 0.78 5.46 0.44 2.45e-7 Eosinophil percentage of granulocytes; TGCT cis rs139371 0.575 rs139347 chr22:39507887 A/G cg18708252 chr22:39545030 CBX7 -0.31 -4.65 -0.39 8.52e-6 Multiple myeloma (IgH translocation);Multiple myeloma (hyperdiploidy); TGCT cis rs2730260 0.537 rs73169234 chr7:158882366 C/T cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs9549367 0.713 rs3024746 chr13:113821777 G/A cg18105134 chr13:113819100 PROZ -0.47 -8.21 -0.59 2.49e-13 Platelet distribution width; TGCT cis rs2721195 0.845 rs2721150 chr8:145724973 C/G cg15857475 chr8:145742913 RECQL4;LRRC14 0.89 9.55 0.65 1.57e-16 Age at first birth; TGCT cis rs6484504 0.576 rs11031324 chr11:31250299 T/C cg26647111 chr11:31128758 NA -0.35 -4.86 -0.4 3.52e-6 Red blood cell count; TGCT cis rs1801251 1.000 rs2592113 chr2:233669553 C/T cg25237894 chr2:233734115 C2orf82 0.3 5.44 0.44 2.74e-7 Coronary artery disease; TGCT cis rs2224391 0.590 rs17140068 chr6:5282227 T/G cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -5.28 -0.43 5.56e-7 Height; TGCT cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg13395646 chr4:1353034 KIAA1530 0.39 4.84 0.4 3.81e-6 Obesity-related traits; TGCT cis rs8180040 0.676 rs11130114 chr3:47154651 T/G cg27129171 chr3:47204927 SETD2 0.76 9.9 0.66 2.25e-17 Colorectal cancer; TGCT cis rs593982 1.000 rs650619 chr11:65506483 G/A cg08755490 chr11:65554678 OVOL1 1.42 12.09 0.74 1.03e-22 Atopic dermatitis; TGCT cis rs2933343 0.700 rs1680788 chr3:128625318 C/T cg11901034 chr3:128598214 ACAD9 -0.63 -6.06 -0.48 1.54e-8 IgG glycosylation; TGCT cis rs17125944 0.505 rs10483617 chr14:53202605 A/G cg00686598 chr14:53173677 PSMC6 -1.07 -5.67 -0.45 9.62e-8 Alzheimer's disease (late onset); TGCT cis rs3791556 0.842 rs55840142 chr2:240106884 G/A cg03281426 chr2:240109471 HDAC4 0.29 4.9 0.4 2.98e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1933488 0.931 rs3870365 chr6:153426932 C/G cg24028809 chr6:153414101 RGS17 0.21 4.67 0.39 7.69e-6 Prostate cancer; TGCT cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT cis rs12477438 0.765 rs2278895 chr2:99613484 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs2075671 0.855 rs11974395 chr7:100282538 G/A cg20848291 chr7:100343083 ZAN -0.52 -4.56 -0.38 1.21e-5 Other erythrocyte phenotypes; TGCT cis rs11122272 0.677 rs2808615 chr1:231550171 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.71 6.89 0.53 2.5e-10 Hemoglobin concentration; TGCT cis rs7659604 1.000 rs7659604 chr4:122665514 A/G cg19748678 chr4:122722346 EXOSC9 -0.5 -4.46 -0.37 1.78e-5 Type 2 diabetes; TGCT cis rs7178572 1.000 rs2055901 chr15:77759295 G/A cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs6988636 0.792 rs62521807 chr8:124163621 T/C cg27053337 chr8:124217698 FAM83A 0.71 5.42 0.44 3e-7 Urinary uromodulin levels; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg25703541 chr22:24373054 LOC391322 -0.81 -8.41 -0.6 8.37e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2204008 0.543 rs2387018 chr12:38065638 C/T cg13010199 chr12:38710504 ALG10B 0.63 5.0 0.41 1.93e-6 Bladder cancer; TGCT cis rs669446 0.561 rs643445 chr1:44089632 C/T cg12908607 chr1:44402522 ARTN 0.54 5.77 0.46 5.93e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs17401966 0.838 rs11121551 chr1:10435170 T/C cg19773385 chr1:10388646 KIF1B -0.23 -5.38 -0.44 3.57e-7 Hepatocellular carcinoma; TGCT cis rs11112613 0.775 rs12371537 chr12:105971425 T/C cg03607813 chr12:105948248 NA 0.47 5.74 0.46 6.71e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs6089584 0.566 rs2181589 chr20:60622817 C/T cg13770153 chr20:60521292 NA 0.39 4.72 0.39 6.35e-6 Body mass index; TGCT cis rs2273156 0.929 rs8017225 chr14:35470049 G/A cg15394648 chr14:35761551 PSMA6 -0.58 -4.63 -0.38 9.15e-6 Immunoglobulin light chain (AL) amyloidosis; TGCT cis rs6964587 1.000 rs28410528 chr7:91647390 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg16497277 chr3:49208875 KLHDC8B -0.53 -5.13 -0.42 1.09e-6 Menarche (age at onset); TGCT cis rs9653442 0.545 rs11681227 chr2:100754997 A/G cg22139774 chr2:100720529 AFF3 -0.37 -5.68 -0.45 8.91e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11719291 0.915 rs9834996 chr3:48754877 G/T cg00383909 chr3:49044727 WDR6 1.02 5.61 0.45 1.24e-7 Cognitive function; TGCT trans rs916888 0.610 rs199529 chr17:44837217 A/C cg22968622 chr17:43663579 NA 1.22 10.97 0.7 5.53e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs922182 0.579 rs4620909 chr15:64192739 C/T cg02919090 chr15:64263738 DAPK2 -0.32 -5.7 -0.46 8.35e-8 Blood protein levels; TGCT cis rs17345786 0.798 rs9817043 chr3:101281852 A/G cg12386194 chr3:101231763 SENP7 0.56 5.39 0.44 3.41e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7264396 0.635 rs6058355 chr20:34491343 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.06 -0.41 1.47e-6 Total cholesterol levels; TGCT trans rs10802346 0.545 rs4478780 chr1:246372241 T/C cg13514129 chr1:39547527 MACF1 0.83 7.33 0.55 2.59e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs9611565 0.649 rs5758466 chr22:42176059 G/A cg06634786 chr22:41940651 POLR3H 0.78 7.31 0.55 2.85e-11 Vitiligo; TGCT cis rs7949030 0.596 rs11231137 chr11:62315699 G/A cg11742103 chr11:62369870 EML3;MTA2 0.55 6.31 0.49 4.46e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1018836 0.786 rs10086401 chr8:91572818 C/T cg16814680 chr8:91681699 NA -0.75 -7.85 -0.58 1.71e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9549367 0.662 rs3818334 chr13:113825174 C/G cg00898013 chr13:113819073 PROZ -0.54 -6.83 -0.52 3.32e-10 Platelet distribution width; TGCT cis rs8177253 0.898 rs8177258 chr3:133480387 C/A cg01448562 chr3:133502909 NA -0.33 -6.71 -0.52 6.07e-10 Iron status biomarkers; TGCT cis rs7726839 0.540 rs3749618 chr5:602650 A/G cg16624210 chr5:671434 TPPP 0.41 4.68 0.39 7.53e-6 Obesity-related traits; TGCT trans rs1974653 0.672 rs74576059 chr22:20079973 G/A cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs28595532 0.920 rs114940990 chr4:119758568 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs72949976 0.606 rs2178756 chr2:214031423 A/G cg08319019 chr2:214017104 IKZF2 0.87 8.64 0.61 2.34e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs28595532 0.920 rs114938162 chr4:119756407 T/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs4919694 1.000 rs77505796 chr10:104647774 A/T cg04362960 chr10:104952993 NT5C2 1.05 6.9 0.53 2.39e-10 Arsenic metabolism; TGCT cis rs2836974 0.644 rs719230 chr21:40676307 C/T cg11644478 chr21:40555479 PSMG1 -0.6 -5.69 -0.46 8.53e-8 Cognitive function; TGCT cis rs2836974 0.897 rs34599551 chr21:40594898 C/A cg11890956 chr21:40555474 PSMG1 1.11 12.32 0.74 2.91e-23 Cognitive function; TGCT cis rs514406 0.861 rs4926576 chr1:53226775 C/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.42e-13 Monocyte count; TGCT cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg20891558 chr2:74357851 NA 0.59 7.36 0.55 2.2e-11 Gestational age at birth (maternal effect); TGCT cis rs7191700 0.578 rs243327 chr16:11353304 C/T cg00044050 chr16:11439710 C16orf75 -0.84 -8.78 -0.62 1.11e-14 Multiple sclerosis; TGCT cis rs295140 1.000 rs55677233 chr2:201168695 T/C cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs60154123 0.730 rs10489391 chr1:210458861 C/T cg22029157 chr1:209979665 IRF6 -0.62 -4.61 -0.38 9.94e-6 Coronary artery disease; TGCT cis rs6088580 0.634 rs6142153 chr20:32968747 C/G cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs6684514 1.000 rs10908494 chr1:156263097 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4713118 0.527 rs36042294 chr6:27720712 C/G cg10876282 chr6:28092338 ZSCAN16 0.5 5.09 0.42 1.29e-6 Parkinson's disease; TGCT cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg10411590 chr13:21900810 NA 0.34 4.56 0.38 1.19e-5 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs4631830 0.720 rs2611475 chr10:51503178 G/A cg10326726 chr10:51549505 MSMB -0.23 -4.64 -0.38 8.74e-6 Prostate-specific antigen levels; TGCT cis rs4700695 0.614 rs153388 chr5:65422308 G/T cg21114390 chr5:65439923 SFRS12 -0.71 -4.81 -0.4 4.37e-6 Facial morphology (factor 19); TGCT cis rs4654899 0.606 rs13376428 chr1:21120027 T/C cg01072550 chr1:21505969 NA -0.53 -8.58 -0.61 3.23e-14 Superior frontal gyrus grey matter volume; TGCT cis rs9467773 0.967 rs9295694 chr6:26512994 A/T cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs614226 0.938 rs12857 chr12:120933946 T/G cg10072921 chr12:121022843 NA -0.42 -4.52 -0.38 1.42e-5 Type 1 diabetes nephropathy; TGCT cis rs6089829 0.890 rs6062775 chr20:61663650 T/C cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs3729931 0.507 rs79945102 chr3:12711975 A/C cg23032965 chr3:12705835 RAF1 0.75 8.05 0.59 5.87e-13 Cardiac hypertrophy; TGCT cis rs2290402 0.536 rs3775127 chr4:886061 G/A cg11315544 chr4:1222440 CTBP1 0.26 4.46 0.37 1.84e-5 Type 2 diabetes; TGCT cis rs12579753 1.000 rs7975863 chr12:82227288 C/T cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs11105298 0.891 rs10858894 chr12:89914261 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.75e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6728642 0.908 rs17842456 chr2:98014319 C/T cg26665480 chr2:98280029 ACTR1B 0.99 5.33 0.43 4.39e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs9765602 1 rs9765602 chr5:35426631 A/G cg21115018 chr5:34597807 NA 0.64 4.84 0.4 3.75e-6 Post bronchodilator FEV1 in COPD; TGCT cis rs3806843 0.966 rs3756338 chr5:140180561 A/G cg19875535 chr5:140030758 IK 0.36 6.11 0.48 1.21e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs6088590 1.000 rs6120705 chr20:33313740 T/C cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT cis rs7246657 0.653 rs10414983 chr19:37665732 T/C cg24025825 chr19:37761650 NA -0.33 -5.06 -0.41 1.49e-6 Coronary artery calcification; TGCT cis rs514406 0.505 rs146750 chr1:53183447 C/G cg24675658 chr1:53192096 ZYG11B -0.79 -9.7 -0.66 6.86e-17 Monocyte count; TGCT cis rs2153535 0.580 rs9505457 chr6:8479142 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs899997 1.000 rs7182694 chr15:79045030 C/T cg04896959 chr15:78267971 NA 0.35 5.07 0.41 1.4e-6 Coronary artery disease or large artery stroke; TGCT cis rs12891047 0.966 rs181572 chr14:68274020 C/G cg26938013 chr14:69015199 RAD51L1 0.44 4.43 0.37 2.02e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9326248 0.954 rs10790177 chr11:117048417 A/G cg26566898 chr11:117069891 TAGLN 0.32 4.54 0.38 1.3e-5 Blood protein levels; TGCT cis rs3784262 0.740 rs12898976 chr15:58276358 A/G cg12031962 chr15:58353849 ALDH1A2 -0.41 -5.93 -0.47 2.74e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6088590 1.000 rs2295354 chr20:33356541 T/C cg06115741 chr20:33292138 TP53INP2 0.67 5.6 0.45 1.34e-7 Coronary artery disease; TGCT cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg18230493 chr5:56204884 C5orf35 -0.67 -5.88 -0.47 3.5e-8 Initial pursuit acceleration; TGCT cis rs2014572 1.000 rs2014572 chr19:57760018 G/A cg24459738 chr19:57751996 ZNF805 -0.56 -5.6 -0.45 1.29e-7 Hyperactive-impulsive symptoms; TGCT cis rs317689 0.600 rs478863 chr12:69639207 G/A cg14784868 chr12:69753453 YEATS4 0.55 4.56 0.38 1.21e-5 Response to diuretic therapy; TGCT cis rs1475911 0.708 rs8129075 chr21:43523430 G/T cg19766460 chr21:43528205 UMODL1;C21orf128 0.61 8.78 0.62 1.07e-14 IgG glycosylation; TGCT cis rs838147 0.508 rs507766 chr19:49208543 T/C cg10667338 chr19:49617042 LIN7B -0.34 -4.57 -0.38 1.18e-5 Dietary macronutrient intake; TGCT cis rs9467773 1.000 rs1884948 chr6:26567988 G/A cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg11861562 chr11:117069780 TAGLN -0.3 -4.72 -0.39 6.39e-6 Blood protein levels; TGCT cis rs896854 0.738 rs527234 chr8:95963798 C/G cg23172400 chr8:95962367 TP53INP1 0.37 5.83 0.46 4.44e-8 Type 2 diabetes; TGCT cis rs10746514 1.000 rs61835640 chr1:232245014 G/A cg09506761 chr1:232265262 NA 0.49 4.98 0.41 2.12e-6 Response to statin therapy; TGCT cis rs736408 0.812 rs9324 chr3:52825585 T/C cg18404041 chr3:52824283 ITIH1 -0.21 -4.58 -0.38 1.12e-5 Bipolar disorder; TGCT cis rs769267 0.930 rs4808964 chr19:19603692 A/C cg03709012 chr19:19516395 GATAD2A -0.74 -6.22 -0.49 7.04e-9 Tonsillectomy; TGCT cis rs1971762 0.762 rs7976793 chr12:54073069 G/T cg22546318 chr12:54070378 ATP5G2 -0.31 -4.48 -0.37 1.68e-5 Height; TGCT cis rs7552404 0.727 rs6678348 chr1:76332463 C/T cg22875332 chr1:76189707 ACADM 0.58 6.08 0.48 1.36e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6882046 0.513 rs187270 chr5:88026870 C/T cg22951263 chr5:87985283 NA -0.54 -5.8 -0.46 5.2100000000000003e-08 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs10089 0.953 rs7713860 chr5:127428789 G/T cg19767477 chr5:127420684 SLC12A2 -0.42 -4.47 -0.37 1.74e-5 Ileal carcinoids; TGCT cis rs5769765 0.954 rs5770709 chr22:50245196 G/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.37 -5.7 -0.46 8.42e-8 Schizophrenia; TGCT cis rs7552404 0.731 rs6699682 chr1:76340123 A/G cg10523679 chr1:76189770 ACADM -0.85 -8.03 -0.58 6.57e-13 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs10953454 1.000 rs10953455 chr7:104503978 T/C cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs2404602 0.716 rs1946650 chr15:76848463 T/C cg22467129 chr15:76604101 ETFA -0.55 -6.51 -0.5 1.65e-9 Blood metabolite levels; TGCT trans rs877282 0.755 rs2486579 chr10:785647 G/A cg22713356 chr15:30763199 NA 0.94 8.1 0.59 4.33e-13 Uric acid levels; TGCT cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg06634786 chr22:41940651 POLR3H -0.86 -7.93 -0.58 1.09e-12 Vitiligo; TGCT cis rs992157 0.835 rs2292551 chr2:219143229 G/A cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6714710 0.603 rs6738389 chr2:98386731 A/G cg26665480 chr2:98280029 ACTR1B 0.66 6.27 0.49 5.45e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs1420338 0.967 rs10271544 chr7:34147159 C/T cg01275685 chr7:34179230 BMPER -0.26 -4.76 -0.39 5.23e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs9325144 0.625 rs11534879 chr12:38968165 A/G cg10518543 chr12:38710700 ALG10B -0.49 -4.68 -0.39 7.26e-6 Morning vs. evening chronotype; TGCT cis rs9372498 0.536 rs72954806 chr6:118899965 C/G cg21191810 chr6:118973309 C6orf204 -0.39 -5.06 -0.41 1.5e-6 Diastolic blood pressure; TGCT cis rs875971 0.862 rs778686 chr7:65835910 C/T cg11764359 chr7:65958608 NA 0.58 5.31 0.43 4.91e-7 Aortic root size; TGCT cis rs9357506 1.000 rs6458500 chr6:46305204 A/G cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.37e-7 Body mass index; TGCT cis rs7772486 0.754 rs702306 chr6:145991029 T/C cg05347473 chr6:146136440 FBXO30 -0.53 -4.95 -0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6570726 0.791 rs440477 chr6:145854188 C/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2295359 0.892 rs12401432 chr1:67656931 C/G cg12940439 chr1:67600707 NA 0.61 6.35 0.5 3.77e-9 Psoriasis; TGCT cis rs597539 0.690 rs608810 chr11:68624118 G/C cg06028808 chr11:68637592 NA 0.56 7.0 0.53 1.43e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9326248 1.000 rs3736120 chr11:117032125 G/T cg26566898 chr11:117069891 TAGLN 0.33 4.55 0.38 1.27e-5 Blood protein levels; TGCT cis rs12477438 0.520 rs6542864 chr2:99725223 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs7659604 1.000 rs7660078 chr4:122665577 G/T cg19748678 chr4:122722346 EXOSC9 0.55 5.31 0.43 4.92e-7 Type 2 diabetes; TGCT cis rs4851266 1.000 rs12991254 chr2:100817933 T/C cg07810366 chr2:100720526 AFF3 -0.41 -5.76 -0.46 6.26e-8 Educational attainment; TGCT cis rs4319547 0.695 rs55834409 chr12:122862560 C/G cg08088222 chr12:122070432 ORAI1 -0.25 -4.49 -0.37 1.58e-5 Body mass index; TGCT cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg23262073 chr20:60523788 NA -0.32 -5.27 -0.43 5.92e-7 Obesity-related traits; TGCT cis rs858239 0.568 rs6970694 chr7:23250828 T/C cg05602783 chr7:23145260 KLHL7 -0.71 -5.45 -0.44 2.55e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg11890956 chr21:40555474 PSMG1 1.13 12.1 0.74 1e-22 Cognitive function; TGCT cis rs13064411 0.696 rs6438161 chr3:113227637 G/A cg18753928 chr3:113234510 CCDC52 -0.71 -5.78 -0.46 5.63e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs1799949 0.965 rs7223952 chr17:41194885 T/C cg05368731 chr17:41323189 NBR1 0.94 9.21 0.64 1.05e-15 Menopause (age at onset); TGCT cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs72781680 0.716 rs17045975 chr2:24099611 A/T cg08917208 chr2:24149416 ATAD2B -0.79 -4.94 -0.41 2.51e-6 Lymphocyte counts; TGCT cis rs1532993 0.518 rs3913986 chr4:98606407 C/T cg05340658 chr4:99064831 C4orf37 -0.37 -4.44 -0.37 1.98e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs1865760 0.568 rs2032450 chr6:25993114 C/G cg17042849 chr6:26104293 HIST1H4C -0.55 -4.8 -0.4 4.4e-6 Height; TGCT cis rs10193935 0.792 rs6735571 chr2:42491951 C/T cg27598129 chr2:42591480 NA -0.32 -4.52 -0.38 1.4e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs3820928 1.000 rs10210763 chr2:227776029 G/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.82 -0.4 4.12e-6 Pulmonary function; TGCT cis rs425277 1.000 rs385039 chr1:2077409 C/T cg24578937 chr1:2090814 PRKCZ -0.32 -8.09 -0.59 4.65e-13 Height; TGCT cis rs116095464 0.558 rs6866632 chr5:264429 C/G cg22857025 chr5:266934 NA -0.35 -6.93 -0.53 2.06e-10 Breast cancer; TGCT cis rs6746896 1.000 rs67570263 chr2:97383007 T/C cg26085987 chr2:97230376 NA 0.19 4.66 0.39 8.15e-6 Bipolar disorder; TGCT cis rs2832191 0.716 rs1888439 chr21:30454457 A/G cg08807101 chr21:30365312 RNF160 0.59 5.86 0.47 3.88e-8 Dental caries; TGCT cis rs2180341 0.889 rs9321074 chr6:127618019 G/A cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs1865760 1.000 rs2071299 chr6:25914801 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.18 0.49 8.59e-9 Height; TGCT cis rs1865760 0.625 rs9393681 chr6:26008260 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.75 7.13 0.54 7.46e-11 Height; TGCT cis rs5769707 0.656 rs135878 chr22:50014369 T/A cg05373962 chr22:49881684 NA -0.3 -4.96 -0.41 2.26e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10504229 0.683 rs55807014 chr8:58131801 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9443189 0.737 rs2842553 chr6:76456632 A/T cg01950844 chr6:76311363 SENP6 -0.6 -4.48 -0.37 1.69e-5 Prostate cancer; TGCT cis rs3935685 0.967 rs62009151 chr15:77999264 C/A cg03457338 chr15:78040120 NA -0.22 -5.12 -0.42 1.13e-6 Intelligence (multi-trait analysis); TGCT cis rs57221529 0.709 rs72706612 chr5:561198 C/T cg09021430 chr5:549028 NA -0.4 -5.48 -0.44 2.24e-7 Lung disease severity in cystic fibrosis; TGCT cis rs72634258 0.503 rs697675 chr1:7838113 A/C cg26816564 chr1:7831052 VAMP3 0.98 7.19 0.54 5.47e-11 Inflammatory bowel disease; TGCT cis rs3733585 0.673 rs9993410 chr4:9951264 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.5 -0.56 1.04e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs910316 1.000 rs7156328 chr14:75532941 T/C cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT trans rs629535 0.814 rs488231 chr8:70064993 T/C cg21567404 chr3:27674614 NA 0.57 8.99 0.63 3.38e-15 Dupuytren's disease; TGCT cis rs7954584 0.567 rs11043251 chr12:122373279 C/T cg21171335 chr12:122356390 WDR66 0.7 7.03 0.53 1.24e-10 Mean corpuscular volume; TGCT cis rs372883 0.600 rs1312254 chr21:30695401 A/G cg24692254 chr21:30365293 RNF160 -0.53 -4.76 -0.39 5.24e-6 Pancreatic cancer; TGCT cis rs6076065 0.802 rs2424527 chr20:23357329 A/C cg11657817 chr20:23433608 CST11 0.31 5.41 0.44 3.07e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs3960554 0.529 rs6465049 chr7:75874489 A/G cg19105122 chr7:75896889 SRRM3 0.55 4.59 0.38 1.08e-5 Eotaxin levels; TGCT cis rs500492 0.618 rs2473158 chr16:1075241 G/A cg02729011 chr16:699500 WDR90 -0.47 -4.43 -0.37 2.01e-5 Polycystic ovary syndrome; TGCT cis rs12477438 0.559 rs6733285 chr2:99725575 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs875971 1.000 rs10257427 chr7:65743208 T/C cg11764359 chr7:65958608 NA -0.61 -5.39 -0.44 3.45e-7 Aortic root size; TGCT cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.546 rs2092274 chr22:42123737 A/G cg13695892 chr22:41940480 POLR3H 0.89 9.04 0.63 2.55e-15 Vitiligo; TGCT cis rs7647973 0.710 rs34890793 chr3:49619493 C/T cg03060546 chr3:49711283 APEH 0.62 5.21 0.42 7.77e-7 Menarche (age at onset); TGCT cis rs10488031 0.557 rs34286271 chr7:37106007 G/T cg06458904 chr7:36312573 EEPD1 0.58 4.79 0.39 4.72e-6 QT interval; TGCT trans rs629535 0.862 rs638412 chr8:70047690 C/T cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs2243480 1.000 rs67536397 chr7:65947917 G/A cg20637647 chr7:64974828 NA 0.91 5.33 0.43 4.55e-7 Diabetic kidney disease; TGCT cis rs3099143 1.000 rs4541044 chr15:77173193 C/T cg21673338 chr15:77095150 SCAPER 0.52 5.05 0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs6951245 0.580 rs10257426 chr7:1213694 G/A cg18402987 chr7:1209562 NA 0.72 6.28 0.49 5.25e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6977660 0.507 rs72591449 chr7:19775443 T/C cg05791153 chr7:19748676 TWISTNB 1.01 6.63 0.51 9.26e-10 Thyroid stimulating hormone; TGCT cis rs11122272 0.766 rs2790871 chr1:231543555 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.71 -0.52 6.09e-10 Hemoglobin concentration; TGCT cis rs12367572 0.965 rs10748405 chr12:45321341 C/G cg04608330 chr12:45269318 NELL2 -0.66 -6.75 -0.52 5.11e-10 Gut microbiome composition (summer); TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg25510823 chr7:47085976 NA 0.44 6.89 0.53 2.5e-10 Breast cancer; TGCT cis rs6912958 0.514 rs7767449 chr6:87887985 A/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.42 -5.44 -0.44 2.74e-7 Monocyte percentage of white cells; TGCT cis rs1982963 0.901 rs2516589 chr14:52512610 A/G cg10843707 chr14:52510701 NID2 -0.43 -6.63 -0.51 9.33e-10 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg03609598 chr5:56110824 MAP3K1 -0.56 -4.57 -0.38 1.14e-5 Initial pursuit acceleration; TGCT cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg18305652 chr10:134549665 INPP5A 0.35 5.94 0.47 2.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6952808 0.609 rs10227517 chr7:1950292 A/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.44 -0.37 1.95e-5 Bipolar disorder and schizophrenia; TGCT cis rs7178572 0.568 rs28524916 chr15:77599002 T/A cg22256960 chr15:77711686 NA 0.85 8.73 0.62 1.4e-14 Type 2 diabetes; TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg06357314 chr7:73275436 WBSCR28 0.29 6.78 0.52 4.39e-10 Phosphorus levels; TGCT cis rs7044106 0.708 rs959558 chr9:123368911 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.58 6.26 0.49 5.67e-9 Hip circumference adjusted for BMI; TGCT cis rs5769707 0.967 rs763127 chr22:50006078 C/T cg10356904 chr22:49881777 NA -0.25 -4.96 -0.41 2.25e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4851254 0.660 rs74340261 chr2:100696827 C/T cg07810366 chr2:100720526 AFF3 -0.47 -4.92 -0.4 2.66e-6 Intelligence (multi-trait analysis); TGCT cis rs17490626 0.568 rs2033371 chr10:71212310 G/A cg12610070 chr10:71211762 TSPAN15 -0.6 -6.99 -0.53 1.47e-10 Thrombosis; TGCT cis rs4654899 0.897 rs12121807 chr1:21069129 A/C cg01072550 chr1:21505969 NA -0.49 -7.89 -0.58 1.37e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7267979 1.000 rs2259873 chr20:25280781 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.654 rs4896829 chr6:145953675 T/A cg23711669 chr6:146136114 FBXO30 0.75 7.84 0.58 1.75e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs10193935 0.901 rs9808509 chr2:42479644 T/C cg27598129 chr2:42591480 NA -0.39 -5.41 -0.44 3.06e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12681288 0.748 rs2701932 chr8:1026946 C/G cg04851639 chr8:1020857 NA -0.34 -6.07 -0.48 1.44e-8 Schizophrenia; TGCT cis rs644799 1.000 rs525404 chr11:95566520 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.88 9.75 0.66 5.14e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs28785552 0.931 rs8113078 chr19:53239084 T/G cg22067481 chr19:53234126 ZNF611 -0.5 -7.33 -0.55 2.6e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT trans rs7618501 0.815 rs3819325 chr3:49843723 T/C cg21665057 chr3:196295764 WDR53;FBXO45 1.02 12.56 0.75 7.47e-24 Intelligence (multi-trait analysis); TGCT cis rs769267 0.929 rs2905424 chr19:19473445 T/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.68 -5.63 -0.45 1.14e-7 Tonsillectomy; TGCT cis rs3796352 1.000 rs7622420 chr3:53111069 A/G cg15956490 chr3:53032818 SFMBT1 0.56 7.22 0.54 4.56e-11 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1949733 1.000 rs6447875 chr4:8503206 T/C cg11789530 chr4:8429930 ACOX3 0.64 5.95 0.47 2.52e-8 Response to antineoplastic agents; TGCT cis rs36051895 0.632 rs11791281 chr9:5172540 G/A cg02405213 chr9:5042618 JAK2 -0.75 -10.25 -0.68 3.13e-18 Pediatric autoimmune diseases; TGCT cis rs10088262 0.629 rs7015861 chr8:124795613 C/T cg02993010 chr8:124780839 FAM91A1 -0.63 -5.14 -0.42 1.05e-6 Pancreatic cancer; TGCT cis rs12579753 0.917 rs10862360 chr12:82187411 A/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs7772486 0.686 rs857883 chr6:145969214 G/T cg05347473 chr6:146136440 FBXO30 -0.49 -4.59 -0.38 1.06e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg13395646 chr4:1353034 KIAA1530 0.38 4.64 0.38 8.74e-6 Obesity-related traits; TGCT cis rs6906287 0.647 rs12192682 chr6:118863594 A/G cg21191810 chr6:118973309 C6orf204 0.27 4.53 0.38 1.36e-5 Electrocardiographic conduction measures; TGCT cis rs17376456 0.877 rs17315943 chr5:93442830 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs12950390 0.853 rs11658511 chr17:45856918 T/C cg03474202 chr17:45855739 NA -0.44 -4.51 -0.38 1.5e-5 IgG glycosylation; TGCT cis rs9911578 1.000 rs11870671 chr17:56605360 A/G cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs6542838 0.702 rs6419564 chr2:99534113 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.44 -0.44 2.74e-7 Fear of minor pain; TGCT cis rs7568458 0.783 rs1561198 chr2:85809989 C/T cg17127132 chr2:85788382 GGCX 0.68 6.16 0.48 9.47e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs154659 1.000 rs154659 chr16:89667337 C/T cg01710450 chr16:89662404 CPNE7 0.37 6.3 0.49 4.76e-9 Tanning; TGCT trans rs986417 0.818 rs761557 chr14:61077484 C/T cg08930843 chr10:31182298 ZNF438 -0.74 -6.73 -0.52 5.48e-10 Gut microbiota (bacterial taxa); TGCT cis rs6840360 0.607 rs2724547 chr4:152365576 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg03188948 chr7:1209495 NA -0.4 -5.2 -0.42 7.93e-7 Longevity;Endometriosis; TGCT cis rs4595586 0.545 rs2218761 chr12:39393593 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg03264133 chr6:25882463 NA -0.5 -4.65 -0.39 8.31e-6 Intelligence (multi-trait analysis); TGCT cis rs854765 0.547 rs9912096 chr17:17896673 A/C cg04398451 chr17:18023971 MYO15A -0.32 -5.12 -0.42 1.15e-6 Total body bone mineral density; TGCT cis rs2836633 1.000 rs2836633 chr21:40067445 C/T cg05519781 chr21:40033154 ERG -0.58 -5.74 -0.46 7e-8 Coronary artery disease; TGCT cis rs4845570 1.000 rs7416415 chr1:151757798 C/T cg07092448 chr1:151763213 TDRKH 1.17 9.47 0.65 2.44e-16 Coronary artery disease; TGCT cis rs13082711 0.554 rs35840701 chr3:27334231 A/C cg02860705 chr3:27208620 NA 0.48 7.57 0.56 7.46e-12 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs317689 0.513 rs317678 chr12:69692166 C/G cg14784868 chr12:69753453 YEATS4 0.66 6.45 0.5 2.31e-9 Response to diuretic therapy; TGCT cis rs10823500 0.777 rs10509321 chr10:71985733 A/G cg04118878 chr10:71993077 PPA1 -0.56 -5.26 -0.43 6.16e-7 Blood protein levels; TGCT cis rs3749237 0.595 rs4855859 chr3:49526300 C/T cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs7772486 0.727 rs2235481 chr6:146056848 T/C cg05347473 chr6:146136440 FBXO30 -0.65 -5.89 -0.47 3.34e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs3809566 1.000 rs4775612 chr15:63332157 T/C cg08198488 chr15:63333792 TPM1 -0.35 -5.23 -0.43 7e-7 Platelet count; TGCT cis rs7772486 0.790 rs7753833 chr6:146161432 C/A cg13319975 chr6:146136371 FBXO30 -0.5 -4.48 -0.37 1.66e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs593982 0.920 rs10896044 chr11:65554680 C/G cg08755490 chr11:65554678 OVOL1 1.41 11.59 0.72 1.74e-21 Atopic dermatitis; TGCT cis rs7432375 0.901 rs900818 chr3:136471815 C/T cg12473912 chr3:136751656 NA -0.36 -5.03 -0.41 1.68e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs2242194 0.816 rs11264296 chr1:154994750 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.57 -5.25 -0.43 6.38e-7 Schizophrenia; TGCT cis rs2204008 0.837 rs11495722 chr12:38337245 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.29 0.55 3.15e-11 Bladder cancer; TGCT cis rs4888262 0.564 rs8050850 chr16:74582597 C/A cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 7.94e-11 Testicular germ cell tumor; TGCT cis rs6688613 0.685 rs742048 chr1:166910145 A/C cg07049167 chr1:166818506 POGK -0.24 -5.17 -0.42 8.99e-7 Refractive astigmatism; TGCT trans rs877282 0.945 rs71491303 chr10:772884 G/T cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs832540 0.656 rs6893754 chr5:56100006 G/A cg24531977 chr5:56204891 C5orf35 -0.51 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs9926296 0.656 rs2376883 chr16:89826926 A/G cg04287289 chr16:89883240 FANCA 0.66 6.63 0.51 9.24e-10 Vitiligo; TGCT cis rs9303401 0.659 rs56162835 chr17:56687315 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs17384381 0.953 rs1498374 chr1:85787334 C/T cg16011679 chr1:85725395 C1orf52 0.84 6.46 0.5 2.2e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs1891275 0.515 rs1361552 chr10:93534624 T/C cg07889827 chr10:93443413 NA -0.32 -6.85 -0.52 3.11e-10 Intelligence (multi-trait analysis); TGCT cis rs7223966 1.000 rs8067064 chr17:61825984 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs10540 1.000 rs61876326 chr11:467368 A/G cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT trans rs2727020 0.595 rs10769583 chr11:49483193 G/A cg03929089 chr4:120376271 NA -0.76 -9.09 -0.63 2.01e-15 Coronary artery disease; TGCT cis rs9902453 0.765 rs2729436 chr17:28120670 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs9796 0.689 rs9888718 chr15:41446254 T/G cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.88 -0.53 2.57e-10 Menopause (age at onset); TGCT cis rs72781680 1.000 rs11553491 chr2:24225901 G/C cg08917208 chr2:24149416 ATAD2B 0.76 4.67 0.39 7.83e-6 Lymphocyte counts; TGCT cis rs4665809 0.887 rs4665814 chr2:26273687 G/T cg04944784 chr2:26401820 FAM59B -0.67 -6.0 -0.47 2.03e-8 Gut microbiome composition (summer); TGCT cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg07424592 chr7:64974309 NA -1.4 -8.42 -0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs2015828 chr4:98984594 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 0.963 rs13011298 chr2:233612996 A/G cg25237894 chr2:233734115 C2orf82 0.32 5.68 0.45 8.93e-8 Coronary artery disease; TGCT cis rs4555082 0.874 rs11625098 chr14:105756891 A/G cg01266790 chr14:105781312 PACS2 0.59 4.86 0.4 3.45e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs6882046 0.513 rs187270 chr5:88026870 C/T cg24804195 chr5:87968844 LOC645323 -0.61 -6.24 -0.49 6.2e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs1008375 0.966 rs758483 chr4:17703614 G/T cg18681998 chr4:17616180 MED28 -0.81 -7.53 -0.56 9.25e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11785400 0.793 rs4371985 chr8:143737279 C/T cg10596483 chr8:143751796 JRK 0.53 5.07 0.41 1.44e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs3857217 chr4:99034347 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9913156 0.793 rs55682338 chr17:4582183 G/A cg23387401 chr17:4582204 PELP1 0.3 4.5 0.37 1.57e-5 Lymphocyte counts; TGCT cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg04267008 chr7:1944627 MAD1L1 -0.41 -5.45 -0.44 2.65e-7 Bipolar disorder and schizophrenia; TGCT cis rs939574 1.000 rs56927225 chr2:220100922 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.05 6.38 0.5 3.13e-9 Platelet distribution width; TGCT cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg17264618 chr3:40429014 ENTPD3 0.33 4.71 0.39 6.52e-6 Renal cell carcinoma; TGCT cis rs854765 0.663 rs3744113 chr17:17748645 T/C cg04398451 chr17:18023971 MYO15A 0.3 4.6 0.38 1.04e-5 Total body bone mineral density; TGCT cis rs832540 1.000 rs192249 chr5:56197514 C/G cg24531977 chr5:56204891 C5orf35 -0.51 -5.12 -0.42 1.14e-6 Coronary artery disease; TGCT trans rs9393777 0.920 rs35869525 chr6:26946687 C/T cg20516262 chr7:155325649 CNPY1 0.63 7.11 0.54 7.99e-11 Intelligence (multi-trait analysis); TGCT cis rs941408 0.515 rs1640262 chr19:2779134 C/T cg26465405 chr19:3039745 TLE2 0.23 4.9 0.4 2.93e-6 Total cholesterol levels; TGCT cis rs7726839 0.540 rs72705102 chr5:659437 T/C cg20362242 chr5:692897 TPPP 0.52 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs40363 0.645 rs250631 chr16:3523215 G/C cg05754148 chr16:3507555 NAT15 0.43 5.12 0.42 1.14e-6 Tuberculosis; TGCT cis rs11809207 1.000 rs41284333 chr1:26517267 A/G cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs7666738 0.830 rs28687737 chr4:99009226 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 0.522 rs73150635 chr7:65972490 C/T cg20637647 chr7:64974828 NA 0.92 5.1 0.42 1.23e-6 Diabetic kidney disease; TGCT cis rs13188771 0.634 rs10043001 chr5:100894557 T/G cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs78245978 0.744 rs2388293 chr10:2632999 A/G cg17670436 chr10:3374199 NA 0.54 4.93 0.41 2.54e-6 Major depressive disorder; TGCT cis rs2153535 0.541 rs9505456 chr6:8479001 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2797780 1.000 rs7774013 chr6:37513945 A/G cg00985040 chr6:37553208 NA 0.25 4.54 0.38 1.34e-5 Systemic lupus erythematosus; TGCT cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg20276088 chr3:133502917 NA 0.27 5.84 0.46 4.32e-8 Iron status biomarkers; TGCT cis rs2067615 0.524 rs7309351 chr12:107077432 C/T cg15890332 chr12:107067104 RFX4 -0.29 -5.77 -0.46 5.9e-8 Heart rate; TGCT cis rs7223966 1.000 rs55674647 chr17:61794195 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.87 0.4 3.27e-6 Hip circumference adjusted for BMI;Body mass index; TGCT trans rs1005277 0.541 rs1740741 chr10:38515334 C/T cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg18230493 chr5:56204884 C5orf35 0.68 6.02 0.48 1.84e-8 Initial pursuit acceleration; TGCT cis rs597539 0.690 rs635529 chr11:68626294 C/T cg04772025 chr11:68637568 NA 0.62 6.77 0.52 4.49e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17030434 1.000 rs79094565 chr4:154718997 T/C cg14289246 chr4:154710475 SFRP2 -0.91 -7.2 -0.54 5.18e-11 Electrocardiographic conduction measures; TGCT cis rs10479542 0.766 rs6894980 chr5:178974592 C/T cg22764044 chr5:178986830 RUFY1 0.43 4.71 0.39 6.55e-6 Lung cancer; TGCT cis rs11172134 0.508 rs1800187 chr12:57587839 C/T cg19258868 chr12:57585184 LRP1 0.34 6.5 0.5 1.81e-9 Urate levels in overweight individuals; TGCT cis rs854765 0.693 rs12941039 chr17:17765655 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.52 -0.44 1.94e-7 Total body bone mineral density; TGCT cis rs6546537 0.915 rs4852866 chr2:69829916 T/C cg10773587 chr2:69614142 GFPT1 -0.66 -5.91 -0.47 3.14e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs447921 0.861 rs4789301 chr17:74454212 A/C cg09812376 chr17:74270190 QRICH2 0.45 4.65 0.39 8.4e-6 Mitochondrial DNA levels; TGCT trans rs6089829 0.962 rs6011548 chr20:61666063 C/T cg23505145 chr19:12996616 KLF1 0.79 8.07 0.59 5.16e-13 Prostate cancer (SNP x SNP interaction); TGCT trans rs9383153 0.590 rs2072736 chr6:16328068 T/C cg22767166 chr8:49833685 SNAI2 0.92 6.66 0.51 7.98e-10 Gambling; TGCT cis rs7666738 0.753 rs11097607 chr4:99011640 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs17685 0.753 rs13240404 chr7:75675719 C/T cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs2486012 0.737 rs246778 chr1:44272761 T/C cg12908607 chr1:44402522 ARTN -0.66 -5.18 -0.42 8.53e-7 Intelligence (multi-trait analysis); TGCT cis rs7959452 0.590 rs28778648 chr12:69771911 C/A cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs7044106 0.762 rs10984972 chr9:123409864 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.59 6.2 0.49 7.76e-9 Hip circumference adjusted for BMI; TGCT cis rs1215050 0.765 rs588851 chr4:98678247 C/T cg05340658 chr4:99064831 C4orf37 0.43 5.4 0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7267979 0.966 rs2500433 chr20:25296335 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6906287 0.647 rs6938226 chr6:118852561 C/A cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs9916302 0.847 rs7218670 chr17:37500424 G/A cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs6088580 0.634 rs6059875 chr20:33086090 T/G cg06115741 chr20:33292138 TP53INP2 0.53 4.65 0.39 8.41e-6 Glomerular filtration rate (creatinine); TGCT cis rs7927771 0.864 rs7107726 chr11:47429245 T/A cg10139015 chr11:47448256 PSMC3 0.52 4.44 0.37 1.97e-5 Subjective well-being; TGCT cis rs11648796 0.757 rs3809666 chr16:764753 C/G cg27144592 chr16:783916 NARFL 0.39 5.46 0.44 2.54e-7 Height; TGCT cis rs12477438 0.520 rs11123762 chr2:99727789 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs2760061 0.598 rs849904 chr1:228137145 G/C cg02753203 chr1:228287806 NA -0.34 -6.56 -0.51 1.33e-9 Diastolic blood pressure; TGCT cis rs367943 1.000 rs348941 chr5:112824166 G/C cg12552261 chr5:112820674 MCC -0.23 -4.57 -0.38 1.17e-5 Type 2 diabetes; TGCT cis rs7937682 0.855 rs521947 chr11:111492616 A/G cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs12049351 0.774 rs6701186 chr1:229626486 C/G cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs231513 0.954 rs231494 chr17:41976928 G/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs72615157 0.664 rs6953580 chr7:99825275 A/G cg00814883 chr7:100076585 TSC22D4 -0.55 -5.42 -0.44 3.01e-7 Lung function (FEV1/FVC); TGCT cis rs2637266 0.667 rs2395405 chr10:78380518 C/T cg18941641 chr10:78392320 NA 0.43 5.53 0.44 1.81e-7 Pulmonary function; TGCT cis rs7666738 0.830 rs6848397 chr4:98946738 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4253772 0.550 rs6007819 chr22:46704916 C/G cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs10883723 0.962 rs11191294 chr10:104225837 T/G cg05855489 chr10:104503620 C10orf26 -0.54 -4.55 -0.38 1.25e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg20007245 chr22:24372913 LOC391322 0.77 6.38 0.5 3.25e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6121246 0.529 rs6060134 chr20:30176794 A/G cg21427119 chr20:30132790 HM13 -0.43 -6.28 -0.49 5.3e-9 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7208859 0.623 rs9900144 chr17:29208389 T/C cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2836974 0.544 rs8128919 chr21:40711862 C/T cg11644478 chr21:40555479 PSMG1 0.65 6.25 0.49 5.89e-9 Cognitive function; TGCT cis rs3741404 0.574 rs638227 chr11:63871549 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.72 7.35 0.55 2.29e-11 Platelet count; TGCT cis rs13256369 1.000 rs7004438 chr8:8574379 C/T cg06671706 chr8:8559999 CLDN23 0.35 4.62 0.38 9.35e-6 Obesity-related traits; TGCT cis rs6121246 0.697 rs6088864 chr20:30228157 G/A cg13852791 chr20:30311386 BCL2L1 0.74 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin; TGCT cis rs425277 0.561 rs11584491 chr1:2042543 A/G cg03732007 chr1:2071316 PRKCZ -0.28 -6.27 -0.49 5.51e-9 Height; TGCT cis rs1406084 0.526 rs13001515 chr2:154720147 A/G cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs79349575 0.783 rs56046215 chr17:47008757 A/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs7582180 0.817 rs1437967 chr2:100929072 C/G cg08017756 chr2:100939284 LONRF2 -0.33 -5.58 -0.45 1.45e-7 Intelligence (multi-trait analysis); TGCT cis rs10875746 0.669 rs11168508 chr12:48683511 G/C cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT trans rs28735056 0.933 rs72980085 chr18:77631679 A/C cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6460942 0.908 rs73677573 chr7:12283598 G/A cg06484146 chr7:12443880 VWDE -0.55 -4.78 -0.39 4.97e-6 Coronary artery disease; TGCT cis rs2204008 0.618 rs8186932 chr12:38338386 G/A cg26384229 chr12:38710491 ALG10B -0.53 -4.66 -0.39 8.04e-6 Bladder cancer; TGCT cis rs3772130 1.000 rs13087578 chr3:121369207 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.89 0.4 3.12e-6 Cognitive performance; TGCT cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg11211951 chr8:145729740 GPT -0.22 -4.99 -0.41 1.95e-6 Age at first birth; TGCT cis rs9303401 0.659 rs36109237 chr17:56653834 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs6500602 0.767 rs8060219 chr16:4480158 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.16 0.42 9.6e-7 Schizophrenia; TGCT cis rs727479 0.543 rs8023263 chr15:51517597 G/T cg19946085 chr15:51559439 CYP19A1 -0.32 -4.71 -0.39 6.49e-6 Estradiol levels; TGCT cis rs11997175 0.574 rs4389890 chr8:33658018 C/T ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs3844412 0.593 rs34409669 chr16:82651234 G/A cg09415485 chr16:82663111 CDH13 0.28 5.11 0.42 1.16e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs7714584 1.000 rs17111376 chr5:150226899 T/C cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs9325144 0.555 rs7977200 chr12:38713745 C/T cg26384229 chr12:38710491 ALG10B 0.68 6.32 0.49 4.19e-9 Morning vs. evening chronotype; TGCT cis rs4786125 0.636 rs11644404 chr16:6904030 C/A cg03623568 chr16:6915990 A2BP1 -0.42 -6.03 -0.48 1.72e-8 Heart rate variability traits (SDNN); TGCT cis rs28595532 0.920 rs116145969 chr4:119770908 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs3096299 0.754 rs2965942 chr16:89510327 G/A cg02187348 chr16:89574699 SPG7 0.62 6.54 0.51 1.42e-9 Multiple myeloma (IgH translocation); TGCT cis rs929354 0.713 rs10085650 chr7:156993413 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs12776158 0.901 rs61848389 chr10:71216569 G/A cg12610070 chr10:71211762 TSPAN15 -0.59 -4.99 -0.41 1.99e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs2463822 0.748 rs2513053 chr11:62109473 T/A cg23876832 chr11:62092739 NA 0.66 4.78 0.39 4.95e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg07092213 chr7:1199455 ZFAND2A -0.41 -4.45 -0.37 1.92e-5 Longevity;Endometriosis; TGCT cis rs10782582 0.593 rs17647178 chr1:76210524 A/G cg10523679 chr1:76189770 ACADM -0.67 -6.71 -0.52 6.18e-10 Daytime sleep phenotypes; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg05064044 chr6:292385 DUSP22 -0.7 -7.14 -0.54 6.88e-11 Menopause (age at onset); TGCT cis rs2637266 1.000 rs10219107 chr10:78364369 T/C cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs7572733 0.536 rs6732517 chr2:198912902 G/C cg00792783 chr2:198669748 PLCL1 0.57 5.03 0.41 1.66e-6 Dermatomyositis; TGCT cis rs9790314 0.730 rs4856705 chr3:161100219 T/G cg03342759 chr3:160939853 NMD3 -0.48 -4.8 -0.4 4.52e-6 Morning vs. evening chronotype; TGCT cis rs6992820 0.967 rs13254746 chr8:56719430 C/G cg06880721 chr8:56792545 LYN -0.53 -4.44 -0.37 1.97e-5 Mean platelet volume; TGCT cis rs6939532 0.522 rs6933583 chr6:26355283 A/C cg05738196 chr6:26577821 NA -0.51 -4.98 -0.41 2.11e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg12667521 chr19:29218732 NA 0.51 6.12 0.48 1.15e-8 Methadone dose in opioid dependence; TGCT cis rs7666738 0.830 rs28417716 chr4:98864859 C/T cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6964587 1.000 rs12666179 chr7:91574110 T/C cg17063962 chr7:91808500 NA -0.91 -10.02 -0.67 1.13e-17 Breast cancer; TGCT cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg20203395 chr5:56204925 C5orf35 -0.56 -4.8 -0.4 4.39e-6 Initial pursuit acceleration; TGCT cis rs3125734 0.633 rs6479791 chr10:63980341 T/C cg19640130 chr10:64028056 RTKN2 -0.39 -5.11 -0.42 1.19e-6 Rheumatoid arthritis; TGCT cis rs854765 0.619 rs4561528 chr17:17979099 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.72 7.52 0.56 9.79e-12 Total body bone mineral density; TGCT cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs8020441 1.000 rs8018822 chr14:51170609 C/T cg04730355 chr14:51134070 SAV1 0.7 5.74 0.46 6.85e-8 Cognitive performance; TGCT cis rs6688613 0.579 rs4657609 chr1:166839174 G/A cg07049167 chr1:166818506 POGK 0.25 5.23 0.43 6.88e-7 Refractive astigmatism; TGCT cis rs9910055 0.529 rs400460 chr17:42182770 A/G cg19774624 chr17:42201019 HDAC5 0.66 6.38 0.5 3.18e-9 Total body bone mineral density; TGCT cis rs7599312 0.534 rs6435711 chr2:213410065 G/A cg16329650 chr2:213403929 ERBB4 1.05 15.34 0.81 1.97e-30 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg04234412 chr22:24373322 LOC391322 -0.92 -10.83 -0.7 1.2e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2013441 1.000 rs11654025 chr17:20198160 A/T cg18979559 chr17:20280153 CCDC144C -0.48 -5.18 -0.42 8.54e-7 Obesity-related traits; TGCT cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg08439880 chr3:133502540 NA -0.28 -5.01 -0.41 1.84e-6 Iron status biomarkers; TGCT cis rs1941184 0.500 rs11873153 chr18:29011968 C/T cg14871544 chr18:29027885 DSG3 0.43 4.57 0.38 1.17e-5 Parkinson's disease (age of onset); TGCT cis rs6121246 0.529 rs7261354 chr20:30202414 T/C cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.39e-6 Mean corpuscular hemoglobin; TGCT cis rs9921338 0.886 rs4780363 chr16:11415891 C/T cg00044050 chr16:11439710 C16orf75 0.97 7.47 0.56 1.25e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg27535305 chr1:53392650 SCP2 0.23 4.52 0.38 1.44e-5 Monocyte count; TGCT cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs284491 0.511 rs35701310 chr8:105961456 T/C cg10331154 chr8:105600724 LRP12 -0.71 -4.5 -0.37 1.52e-5 Glaucoma (low intraocular pressure); TGCT cis rs6988636 0.818 rs62521808 chr8:124169568 C/T cg27053337 chr8:124217698 FAM83A 0.67 4.77 0.39 5.15e-6 Urinary uromodulin levels; TGCT cis rs1865760 1.000 rs6910138 chr6:25904352 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs8180040 0.627 rs9821119 chr3:47198437 C/G cg27129171 chr3:47204927 SETD2 0.7 8.33 0.6 1.26e-13 Colorectal cancer; TGCT cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT trans rs1974653 0.672 rs9606234 chr22:20067517 T/G cg08822737 chr17:71088851 SLC39A11 -0.92 -7.35 -0.55 2.29e-11 Schizophrenia; TGCT cis rs763121 0.853 rs5750662 chr22:39072472 G/A cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT trans rs561341 1.000 rs113115092 chr17:30284164 G/A cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs11690935 0.877 rs72890834 chr2:172835802 G/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -11.86 -0.73 3.8e-22 Schizophrenia; TGCT cis rs8020441 0.945 rs61238948 chr14:51167617 A/G cg04730355 chr14:51134070 SAV1 0.71 5.77 0.46 5.92e-8 Cognitive performance; TGCT cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs17767294 0.614 rs72854521 chr6:28284798 T/A cg08851530 chr6:28072375 NA 1.54 6.89 0.53 2.51e-10 Parkinson's disease; TGCT cis rs12765878 0.756 rs6584579 chr10:105645725 A/G cg04788957 chr10:105438008 SH3PXD2A 0.28 4.52 0.38 1.44e-5 Coronary artery disease; TGCT cis rs7666738 0.791 rs7658177 chr4:99035192 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs975752 0.867 rs61166818 chr10:102032865 G/A cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs4699052 0.507 rs6533085 chr4:104281586 A/T cg16532752 chr4:104119610 CENPE -0.75 -6.26 -0.49 5.8e-9 Testicular germ cell tumor; TGCT cis rs3821902 0.501 rs6799578 chr3:63745668 C/A cg22134162 chr3:63841271 THOC7 -0.3 -4.58 -0.38 1.12e-5 Breast cancer; TGCT cis rs523522 0.962 rs655530 chr12:121022275 T/C cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT trans rs7824557 0.547 rs4512344 chr8:11078781 A/C cg15556689 chr8:8085844 FLJ10661 -0.86 -8.37 -0.6 1.01e-13 Retinal vascular caliber; TGCT cis rs7914558 1.000 rs6584540 chr10:104927634 A/G cg04362960 chr10:104952993 NT5C2 0.61 5.45 0.44 2.6e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12681287 0.547 rs6998303 chr8:87510185 T/C cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs8177253 1.000 rs8177253 chr3:133480192 A/G cg08439880 chr3:133502540 NA 0.33 6.17 0.48 9.01e-9 Iron status biomarkers; TGCT cis rs854765 0.547 rs6502632 chr17:17913057 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.27 0.6 1.72e-13 Total body bone mineral density; TGCT cis rs2095921 1 rs2095921 chr1:11033322 C/G cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Male-pattern baldness; TGCT cis rs10276381 0.579 rs73072543 chr7:28146850 A/G cg23620719 chr7:28220237 JAZF1 0.74 4.5 0.37 1.56e-5 Crohn's disease; TGCT cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg08439880 chr3:133502540 NA 0.27 4.97 0.41 2.17e-6 Iron status biomarkers; TGCT cis rs2836974 0.897 rs36113648 chr21:40555497 G/A cg17971929 chr21:40555470 PSMG1 0.96 9.01 0.63 3.05e-15 Cognitive function; TGCT cis rs10193935 0.901 rs10202848 chr2:42515661 A/G cg27598129 chr2:42591480 NA -0.42 -5.72 -0.46 7.48e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7927771 0.864 rs4752999 chr11:47428565 C/T cg21462715 chr11:47870315 NUP160 0.58 4.5 0.37 1.52e-5 Subjective well-being; TGCT cis rs7208859 0.623 rs7503542 chr17:29073830 A/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs34734847 0.842 rs556001 chr12:121152967 A/G cg21892295 chr12:121157589 UNC119B -0.21 -4.94 -0.41 2.47e-6 Mean corpuscular volume; TGCT cis rs7949030 0.626 rs71490390 chr11:62329185 A/G cg11742103 chr11:62369870 EML3;MTA2 0.61 8.71 0.62 1.65e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9388451 0.839 rs1811852 chr6:126071575 G/C cg10911889 chr6:126070802 HEY2 0.57 6.06 0.48 1.51e-8 Brugada syndrome; TGCT cis rs9467711 1.000 rs34569761 chr6:26334306 A/G cg26531700 chr6:26746687 NA -1.04 -5.71 -0.46 7.81e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs4849845 0.598 rs4848586 chr2:121061291 C/T cg24070213 chr2:121070622 NA 0.35 4.72 0.39 6.29e-6 Mean platelet volume; TGCT trans rs6089829 0.962 rs6122350 chr20:61664617 A/G cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs372883 0.519 rs2832274 chr21:30600189 A/T cg24692254 chr21:30365293 RNF160 0.6 5.61 0.45 1.23e-7 Pancreatic cancer; TGCT cis rs28595532 1.000 rs75497896 chr4:119636703 T/C cg11846333 chr4:119757529 SEC24D 0.95 4.68 0.39 7.54e-6 Cannabis dependence symptom count; TGCT cis rs1862618 0.671 rs2591965 chr5:56236176 T/C cg12311346 chr5:56204834 C5orf35 0.57 6.13 0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs6733011 0.628 rs4263159 chr2:99456151 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.46 -4.64 -0.38 8.7e-6 Bipolar disorder; TGCT cis rs11122272 0.735 rs2739516 chr1:231505527 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs9913156 0.639 rs72824971 chr17:4604270 A/G cg19197139 chr17:4613644 ARRB2 0.86 7.87 0.58 1.5e-12 Lymphocyte counts; TGCT cis rs2594989 0.943 rs2454493 chr3:11506458 A/G cg00170343 chr3:11313890 ATG7 0.74 5.47 0.44 2.4e-7 Circulating chemerin levels; TGCT cis rs7655841 0.704 rs28711799 chr4:129874496 T/A cg26347359 chr4:129759716 PHF17 0.43 4.81 0.4 4.37e-6 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs10751667 0.714 rs7395879 chr11:963855 G/C cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT trans rs853356 0.947 rs853384 chr6:14182305 T/G cg14262035 chr17:42019790 PPY 0.5 6.73 0.52 5.54e-10 Height; TGCT cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.46 0.44 2.53e-7 Height; TGCT cis rs9894429 0.966 rs7405901 chr17:79587813 T/C cg18240062 chr17:79603768 NPLOC4 0.67 6.85 0.52 3.11e-10 Eye color traits; TGCT cis rs539096 0.706 rs618369 chr1:44071796 G/T cg12908607 chr1:44402522 ARTN -0.49 -4.94 -0.41 2.49e-6 Intelligence (multi-trait analysis); TGCT cis rs10832169 0.967 rs1528640 chr11:14070828 A/G cg04547675 chr11:13986162 SPON1 0.54 4.78 0.39 4.9100000000000004e-06 Blood protein levels; TGCT trans rs1814175 0.529 rs1988417 chr11:49932430 A/G cg18944383 chr4:111397179 ENPEP 0.45 6.9 0.53 2.36e-10 Height; TGCT cis rs4819052 0.851 rs4819044 chr21:46660118 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.78 0.52 4.27e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12497850 1.000 rs4858828 chr3:48724811 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.94 0.47 2.65e-8 Parkinson's disease; TGCT cis rs7927592 0.763 rs10896327 chr11:68235275 G/C cg16797656 chr11:68205561 LRP5 0.26 4.54 0.38 1.29e-5 Total body bone mineral density; TGCT cis rs9818758 0.607 rs35283189 chr3:49113668 T/C cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg11301795 chr4:187892539 NA -0.33 -4.88 -0.4 3.19e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9807841 0.670 rs10948 chr19:10754905 G/T cg17848348 chr19:10766748 ILF3 -0.4 -4.5 -0.37 1.55e-5 Inflammatory skin disease; TGCT cis rs17608059 0.710 rs8080167 chr17:13949828 G/A cg11395062 chr17:14139857 CDRT15 0.39 5.08 0.41 1.36e-6 Temperament; TGCT cis rs1475911 1.000 rs1475911 chr21:43513480 A/C cg14562523 chr21:43528734 C21orf128;UMODL1 -0.26 -5.21 -0.42 7.57e-7 IgG glycosylation; TGCT cis rs74233809 1.000 rs11191515 chr10:104776527 G/A cg05855489 chr10:104503620 C10orf26 0.77 4.55 0.38 1.27e-5 Birth weight; TGCT cis rs2760061 0.624 rs10442629 chr1:228191070 T/A cg18477163 chr1:228402036 OBSCN 0.36 7.06 0.54 1.04e-10 Diastolic blood pressure; TGCT cis rs10791097 0.547 rs1050078 chr11:130746146 T/C cg05962950 chr11:130786565 SNX19 0.93 11.63 0.72 1.37e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12478296 0.786 rs13409307 chr2:242995499 G/C cg06360820 chr2:242988706 NA -0.63 -5.43 -0.44 2.86e-7 Obesity-related traits; TGCT cis rs28595532 0.920 rs116046128 chr4:119741990 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4689388 0.853 rs6817447 chr4:6286847 G/T cg25554036 chr4:6271136 WFS1 0.56 7.96 0.58 9.45e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10791323 0.592 rs2851115 chr11:133705381 C/A cg15485101 chr11:133734466 NA 0.41 5.18 0.42 8.59e-7 Childhood ear infection; TGCT cis rs12989701 0.825 rs4663096 chr2:127861766 T/A cg08168897 chr2:127865431 BIN1 0.55 6.59 0.51 1.13e-9 Alzheimer's disease (late onset); TGCT cis rs911555 0.755 rs7148567 chr14:103882234 C/T cg23461800 chr14:103021989 NA 0.33 4.46 0.37 1.83e-5 Intelligence (multi-trait analysis); TGCT cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs6740322 0.948 rs6722694 chr2:43569798 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.17 -0.48 8.72e-9 Coronary artery disease; TGCT cis rs79387448 0.745 rs1989399 chr2:103166742 G/A cg09003973 chr2:102972529 NA 0.95 6.15 0.48 9.95e-9 Gut microbiota (bacterial taxa); TGCT cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg03452623 chr4:187889614 NA -0.36 -5.3 -0.43 5.01e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10254284 0.959 rs881850 chr7:28152675 C/T cg23620719 chr7:28220237 JAZF1 -0.54 -4.79 -0.4 4.7e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs6570726 0.935 rs429306 chr6:145827016 T/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6582630 0.519 rs8189599 chr12:38280748 A/G cg13010199 chr12:38710504 ALG10B 0.6 4.62 0.38 9.49e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs10057188 0.868 rs35252676 chr5:77916444 C/T cg24853438 chr5:77139492 NA -0.22 -4.47 -0.37 1.74e-5 Pulse pressure; TGCT cis rs1552244 0.882 rs13077641 chr3:10022935 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs7829975 0.511 rs2976906 chr8:8342415 A/T cg08975724 chr8:8085496 FLJ10661 0.55 5.37 0.43 3.82e-7 Mood instability; TGCT cis rs7666738 0.830 rs6854994 chr4:98977624 C/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 0.698 rs72677589 chr1:46817770 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs2404602 0.679 rs12899871 chr15:76757347 T/C cg22467129 chr15:76604101 ETFA -0.57 -6.83 -0.52 3.31e-10 Blood metabolite levels; TGCT cis rs617219 0.726 rs955897 chr5:78431486 A/C cg09550809 chr5:78407562 BHMT 0.4 5.43 0.44 2.88e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7524258 0.867 rs35399313 chr1:7277293 T/C cg07173049 chr1:7289937 CAMTA1 0.28 4.55 0.38 1.27e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs1577917 0.917 rs4098044 chr6:86462066 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.27 -0.43 5.96e-7 Response to antipsychotic treatment; TGCT cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs704795 0.775 rs4665975 chr2:27626017 A/T cg12000995 chr2:27665139 KRTCAP3 -0.37 -4.74 -0.39 5.83e-6 Menopause (age at onset); TGCT cis rs1552244 0.608 rs2075310 chr3:10067651 C/T cg00149659 chr3:10157352 C3orf10 0.82 5.99 0.47 2.09e-8 Alzheimer's disease; TGCT cis rs3806843 0.900 rs2563287 chr5:140124786 C/T cg26465581 chr5:140221106 PCDHA6;PCDHA2;PCDHA1;PCDHA7;PCDHA8;PCDHA5;PCDHA3;PCDHA4 -0.3 -4.61 -0.38 1e-5 Depressive symptoms (multi-trait analysis); TGCT trans rs1814175 0.645 rs28634872 chr11:50042175 T/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs11785400 0.793 rs4371985 chr8:143737279 C/T cg24634471 chr8:143751801 JRK 0.54 5.11 0.42 1.19e-6 Schizophrenia; TGCT cis rs9311474 0.596 rs524986 chr3:52228496 T/C cg07507251 chr3:52567010 NT5DC2 0.35 4.56 0.38 1.19e-5 Electroencephalogram traits; TGCT cis rs2458413 0.542 rs2514670 chr8:105363452 C/G cg04554929 chr8:105342491 NA -0.49 -5.88 -0.47 3.59e-8 Paget's disease; TGCT cis rs208520 0.526 rs7771233 chr6:66819784 A/G cg07460842 chr6:66804631 NA -0.97 -11.82 -0.73 4.61e-22 Exhaled nitric oxide output; TGCT trans rs2243480 1.000 rs1638734 chr7:66097539 A/C cg07424592 chr7:64974309 NA 1.31 7.65 0.57 4.73e-12 Diabetic kidney disease; TGCT cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs3820068 0.608 rs10927836 chr1:16034368 G/C cg05660106 chr1:15850417 CASP9 0.69 6.45 0.5 2.28e-9 Systolic blood pressure; TGCT cis rs6088590 0.710 rs6059992 chr20:33282275 T/C cg06115741 chr20:33292138 TP53INP2 0.56 4.7 0.39 6.83e-6 Coronary artery disease; TGCT cis rs4699052 0.739 rs6836157 chr4:104242990 A/G cg16532752 chr4:104119610 CENPE -0.54 -5.43 -0.44 2.87e-7 Testicular germ cell tumor; TGCT cis rs7226408 0.857 rs56391099 chr18:34478627 G/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9534288 0.830 rs7987953 chr13:46634395 C/T cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs3011225 0.710 rs3011224 chr1:44318483 C/T cg12908607 chr1:44402522 ARTN -0.64 -7.74 -0.57 3e-12 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs67340775 0.541 rs200974 chr6:27855845 A/G cg26587870 chr6:27730563 NA -0.34 -4.62 -0.38 9.28e-6 Lung cancer in ever smokers; TGCT cis rs644799 0.672 rs61902245 chr11:95517737 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.28 0.6 1.63e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg20203395 chr5:56204925 C5orf35 0.79 6.24 0.49 6.41e-9 Initial pursuit acceleration; TGCT trans rs1814175 0.669 rs12416837 chr11:49669761 G/T cg15704280 chr7:45808275 SEPT13 -0.61 -7.11 -0.54 8.12e-11 Height; TGCT cis rs73198271 1.000 rs55971558 chr8:8614403 G/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.79 -0.39 4.72e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs10193935 0.818 rs2374428 chr2:42667961 T/C cg27598129 chr2:42591480 NA 0.38 5.41 0.44 3.09e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1334894 0.892 rs11545925 chr6:35542526 T/A cg24281267 chr6:35479648 TULP1 -0.44 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT trans rs7618501 0.602 rs10049087 chr3:50123417 A/G cg21659725 chr3:3221576 CRBN -0.74 -8.78 -0.62 1.08e-14 Intelligence (multi-trait analysis); TGCT cis rs514406 0.505 rs269289 chr1:53167151 A/C cg22166914 chr1:53195759 ZYG11B 0.44 7.58 0.56 6.98e-12 Monocyte count; TGCT cis rs26868 0.816 rs26871 chr16:2248133 G/A cg25665528 chr16:2260870 C16orf79 -0.31 -4.79 -0.4 4.62e-6 Height; TGCT cis rs763014 0.966 rs4984677 chr16:671682 A/G cg27436995 chr16:743998 FBXL16 -0.47 -5.11 -0.42 1.17e-6 Height; TGCT cis rs492146 0.765 rs673197 chr6:52844257 A/G cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg10150615 chr22:24372951 LOC391322 -1.0 -12.85 -0.76 1.47e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2439831 0.850 rs2277531 chr15:44069069 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.86 5.7 0.46 8.13e-8 Lung cancer in ever smokers; TGCT cis rs1670533 1.000 rs629260 chr4:1086764 A/G cg20887711 chr4:1340912 KIAA1530 0.66 5.33 0.43 4.49e-7 Recombination rate (females); TGCT cis rs60843830 1.000 rs10193373 chr2:281886 T/G cg25945732 chr2:264204 ACP1;SH3YL1 0.73 7.33 0.55 2.65e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs62380364 0.542 rs2247885 chr5:88047999 T/C cg24804195 chr5:87968844 LOC645323 -0.58 -5.68 -0.45 9.18e-8 Intelligence (multi-trait analysis); TGCT cis rs4727027 0.866 rs3735311 chr7:148877737 T/C cg23583168 chr7:148888333 NA -0.74 -9.81 -0.66 3.64e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6725041 0.819 rs939224 chr2:213089095 T/C cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs4689388 0.853 rs1079216 chr4:6282473 T/C cg14416269 chr4:6271139 WFS1 0.4 5.13 0.42 1.07e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg07332563 chr6:291687 DUSP22 -0.76 -7.73 -0.57 3.11e-12 Menopause (age at onset); TGCT cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.58 -5.67 -0.45 9.32e-8 Intelligence (multi-trait analysis); TGCT cis rs7089973 0.628 rs11196953 chr10:116607707 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs13108904 0.557 rs1250095 chr4:1239312 C/T cg19318889 chr4:1322082 MAEA -0.2 -4.91 -0.4 2.8e-6 Obesity-related traits; TGCT cis rs617219 0.671 rs2607144 chr5:78556798 G/T cg23987322 chr5:78407566 BHMT 0.39 4.98 0.41 2.1e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs12681287 0.547 rs7461366 chr8:87511685 C/T cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs875971 0.965 rs10267430 chr7:65743023 G/T cg18876405 chr7:65276391 NA -0.34 -5.08 -0.41 1.38e-6 Aortic root size; TGCT cis rs10089 0.951 rs1864923 chr5:127420843 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.8 7.64 0.57 5.24e-12 Ileal carcinoids; TGCT cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg10349874 chr16:420996 TMEM8A;MRPL28 -0.25 -4.48 -0.37 1.7e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs1670533 1.000 rs6852850 chr4:1052857 C/G cg20887711 chr4:1340912 KIAA1530 0.7 5.65 0.45 1.03e-7 Recombination rate (females); TGCT trans rs4332037 0.950 rs56403963 chr7:1946130 C/G cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT trans rs1973993 0.967 rs2181375 chr1:96940119 A/G cg10631902 chr5:14652156 NA 0.31 6.82 0.52 3.6e-10 Weight; TGCT cis rs7772486 0.817 rs2144477 chr6:146406248 C/T cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs34779708 0.931 rs4934524 chr10:35270921 G/C cg04310649 chr10:35416472 CREM -0.51 -4.54 -0.38 1.31e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg23156509 chr2:114033830 PAX8;LOC440839 -0.31 -4.83 -0.4 3.92e-6 Lymphocyte counts; TGCT cis rs8013055 0.846 rs11624007 chr14:105992183 A/C cg23356831 chr14:105996513 TMEM121 0.36 5.43 0.44 2.85e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs765787 0.530 rs11636440 chr15:45535982 C/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs28374715 0.681 rs7165396 chr15:41586947 T/C cg18705301 chr15:41695430 NDUFAF1 -0.89 -13.11 -0.76 3.54e-25 Ulcerative colitis; TGCT cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs478304 0.651 rs4014192 chr11:65498915 C/T cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.05e-10 Acne (severe); TGCT cis rs1903068 0.853 rs9997685 chr4:56022903 A/T cg16572876 chr4:56024045 NA 0.44 4.76 0.39 5.27e-6 Endometriosis; TGCT cis rs9911578 0.835 rs723991 chr17:56482039 G/A cg05425664 chr17:57184151 TRIM37 0.61 5.73 0.46 7.03e-8 Intelligence (multi-trait analysis); TGCT cis rs77972916 0.536 rs59362315 chr2:43594931 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.06 -0.48 1.52e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs17490626 0.512 rs12241097 chr10:71216678 T/G cg12610070 chr10:71211762 TSPAN15 -0.62 -7.12 -0.54 7.54e-11 Thrombosis; TGCT cis rs2204008 0.837 rs2892296 chr12:37969785 C/T cg26384229 chr12:38710491 ALG10B -0.7 -6.12 -0.48 1.11e-8 Bladder cancer; TGCT cis rs7666738 0.830 rs921522 chr4:98841608 C/T cg18180107 chr4:99064573 C4orf37 0.6 5.25 0.43 6.5e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1341267 0.529 rs6492721 chr13:95258944 A/G cg18412871 chr13:95254051 GPR180 -0.6 -5.45 -0.44 2.66e-7 Triglyceride levels; TGCT cis rs7246657 0.943 rs10405064 chr19:37861861 C/T cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs453301 0.686 rs2409120 chr8:8882571 G/C cg06636001 chr8:8085503 FLJ10661 -0.68 -5.66 -0.45 9.87e-8 Joint mobility (Beighton score); TGCT cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg23719950 chr11:63933701 MACROD1 -0.72 -6.01 -0.47 1.92e-8 Mean platelet volume; TGCT cis rs12474538 0.704 rs10209687 chr2:69508284 C/T cg24886176 chr2:70142158 MXD1 0.71 4.52 0.38 1.43e-5 Breast cancer; TGCT cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg11301795 chr4:187892539 NA -0.3 -4.49 -0.37 1.62e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9796 0.689 rs561301 chr15:41444723 C/T cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.84 -0.52 3.16e-10 Menopause (age at onset); TGCT cis rs4944092 1.000 rs7125695 chr11:75908131 A/G cg04588336 chr11:75916460 WNT11 0.44 6.09 0.48 1.29e-8 PR interval; TGCT cis rs9436747 0.740 rs1171265 chr1:66003252 A/G cg14976592 chr1:65886160 LEPROT;LEPR -0.5 -4.85 -0.4 3.57e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs8038465 0.592 rs1542579 chr15:73935897 A/G cg15420318 chr15:73925796 NPTN 0.64 6.67 0.51 7.56e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11651000 0.625 rs4794067 chr17:45808828 T/C cg06532163 chr17:45867833 NA 0.33 5.21 0.42 7.7300000000000005e-07 IgG glycosylation; TGCT cis rs8072100 1.000 rs8065437 chr17:45721653 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.13 -0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9916302 0.904 rs35335692 chr17:37710006 A/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs3734905 0.831 rs12529773 chr6:169926440 G/C cg20469989 chr6:170102314 C6orf120;WDR27 -0.97 -5.18 -0.42 8.62e-7 HIV-1 control; TGCT cis rs7666738 0.830 rs7672901 chr4:98938781 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12579753 0.917 rs10778833 chr12:82197983 G/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs4819052 0.851 rs2838833 chr21:46665160 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.62 5.04 0.41 1.63e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs875971 0.964 rs2277911 chr7:65958625 T/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs9581857 0.547 rs9319374 chr13:28047587 A/C cg22138327 chr13:27999177 GTF3A 0.74 4.82 0.4 4.15e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.45 4.65 0.39 8.33e-6 Lymphocyte counts; TGCT cis rs7119038 0.818 rs10892288 chr11:118644694 A/G cg19308663 chr11:118741387 NA 0.31 6.12 0.48 1.14e-8 Sjögren's syndrome; TGCT cis rs4478858 0.735 rs6681286 chr1:31799384 G/C cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs17221829 0.965 rs10830364 chr11:89458632 T/G cg02982614 chr11:89391479 FOLH1B -0.27 -4.66 -0.39 8.19e-6 Anxiety in major depressive disorder; TGCT cis rs380904 0.963 rs410822 chr8:144574611 A/C cg22012530 chr8:144635309 GSDMD 0.47 4.9 0.4 2.99e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs3796352 1.000 rs2336540 chr3:52974589 G/A cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8084125 0.832 rs62105180 chr18:74951197 C/G cg05528293 chr18:74961138 GALR1 0.52 5.18 0.42 8.65e-7 Obesity-related traits; TGCT cis rs9915657 0.870 rs1042678 chr17:70122108 G/A cg06234051 chr17:70120541 SOX9 -0.26 -5.34 -0.43 4.36e-7 Thyroid hormone levels; TGCT cis rs4919044 0.808 rs835256 chr10:94779550 C/T cg05127821 chr10:94822908 CYP26C1 -0.77 -5.03 -0.41 1.71e-6 Coronary artery disease; TGCT cis rs9972944 0.729 rs7222147 chr17:63774100 C/T cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs4665809 1.000 rs1560868 chr2:26281459 A/T cg22920501 chr2:26401640 FAM59B 0.7 6.28 0.49 5.13e-9 Gut microbiome composition (summer); TGCT cis rs992157 0.767 rs2014615 chr2:219171191 A/G cg00012203 chr2:219082015 ARPC2 0.81 7.91 0.58 1.2e-12 Colorectal cancer; TGCT cis rs1670533 1.000 rs935972 chr4:1045171 A/G cg18657303 chr4:1051139 NA 0.3 4.46 0.37 1.79e-5 Recombination rate (females); TGCT cis rs3858526 0.883 rs4758183 chr11:5925178 C/G cg13902645 chr11:5959945 NA -0.43 -4.62 -0.38 9.28e-6 DNA methylation (variation); TGCT cis rs13191362 1.000 rs13206253 chr6:163166902 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.88 7.89 0.58 1.34e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7726839 0.540 rs72703087 chr5:598029 C/T cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs7959452 0.640 rs1598543 chr12:69688757 G/T cg20891283 chr12:69753455 YEATS4 0.66 6.57 0.51 1.26e-9 Blood protein levels; TGCT cis rs7760949 1.000 rs7760949 chr6:13920538 A/C cg27413430 chr6:13925136 RNF182 0.64 5.97 0.47 2.32e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs6426558 0.515 rs7412928 chr1:227332148 C/T cg10327440 chr1:227177885 CDC42BPA -0.57 -6.65 -0.51 8.31e-10 Neutrophil percentage of white cells; TGCT cis rs1577917 0.958 rs884842 chr6:86680397 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.39e-7 Response to antipsychotic treatment; TGCT cis rs137603 0.966 rs126228 chr22:39681436 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.57 5.3 0.43 5.05e-7 Primary biliary cholangitis; TGCT cis rs3087591 1.000 rs2905884 chr17:29512476 A/G cg24425628 chr17:29625626 OMG;NF1 0.46 7.04 0.53 1.17e-10 Hip circumference; TGCT cis rs1062177 1.000 rs2915880 chr5:151147334 G/A cg12924095 chr5:151150029 G3BP1 0.35 5.07 0.41 1.41e-6 Preschool internalizing problems; TGCT cis rs2797160 0.904 rs1739370 chr6:126011231 C/T cg05901451 chr6:126070800 HEY2 0.76 6.58 0.51 1.19e-9 Endometrial cancer; TGCT cis rs2456568 0.900 rs2511373 chr11:93671414 T/C cg17595323 chr11:93583763 C11orf90 -0.46 -5.86 -0.47 3.88e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836950 0.565 rs2836945 chr21:40596757 C/T cg11644478 chr21:40555479 PSMG1 -0.54 -5.1 -0.42 1.25e-6 Menarche (age at onset); TGCT cis rs910316 1.000 rs7147118 chr14:75610170 G/C cg11812906 chr14:75593930 NEK9 0.74 7.37 0.55 2.12e-11 Height; TGCT cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg08048268 chr3:133502702 NA 0.7 11.4 0.72 4.94e-21 Iron status biomarkers; TGCT cis rs909674 0.818 rs8136980 chr22:39844574 G/A cg02038168 chr22:39784481 NA -0.7 -5.63 -0.45 1.16e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4499344 0.921 rs2277927 chr19:33088366 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.73 6.69 0.51 6.9e-10 Mean platelet volume; TGCT cis rs8072100 0.875 rs9635762 chr17:45648446 A/C cg08085267 chr17:45401833 C17orf57 0.43 4.63 0.38 9.02e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs8037137 0.915 rs77554484 chr15:91509215 C/A cg22570213 chr15:91497863 RCCD1 0.54 5.04 0.41 1.6e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs2075165 0.901 rs7522860 chr1:156275281 C/T cg20302342 chr1:156215951 PAQR6 0.34 5.24 0.43 6.83e-7 Tonsillectomy; TGCT cis rs1129187 0.935 rs9462859 chr6:42946943 G/A cg18735214 chr6:43276756 CRIP3 -0.56 -4.84 -0.4 3.78e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg01802117 chr1:53393560 SCP2 0.5 6.08 0.48 1.36e-8 Monocyte count; TGCT cis rs11621121 0.637 rs4902387 chr14:65792839 C/T cg04536575 chr14:65016802 C14orf50 -0.64 -4.53 -0.38 1.36e-5 N-glycan levels; TGCT cis rs2580764 0.517 rs2972070 chr2:55301691 G/A cg09592903 chr2:55203963 RTN4 0.25 5.64 0.45 1.09e-7 Mean platelet volume; TGCT cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467711 0.606 rs9393713 chr6:26373678 C/T cg16898833 chr6:26189333 HIST1H4D 1.07 5.08 0.41 1.36e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg27286337 chr10:134555280 INPP5A 0.38 4.57 0.38 1.17e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4478858 0.709 rs7514640 chr1:31752316 G/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs2120019 0.938 rs2289582 chr15:75310394 T/C cg09165964 chr15:75287851 SCAMP5 -1.18 -10.31 -0.68 2.22e-18 Blood trace element (Zn levels); TGCT cis rs2242116 0.727 rs6442040 chr3:46963035 C/A cg27129171 chr3:47204927 SETD2 0.62 6.08 0.48 1.36e-8 Birth weight; TGCT cis rs12142240 0.698 rs56284503 chr1:46847127 C/G cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs899997 1.000 rs11634628 chr15:79005579 G/A cg04896959 chr15:78267971 NA 0.36 5.57 0.45 1.52e-7 Coronary artery disease or large artery stroke; TGCT cis rs8013055 0.699 rs66798104 chr14:105987782 C/G cg23356831 chr14:105996513 TMEM121 0.36 5.5 0.44 2.12e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs3784262 0.669 rs4646623 chr15:58257123 T/G cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.11 -0.48 1.19e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs916888 0.821 rs199509 chr17:44858728 G/A cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6500602 0.727 rs1477123 chr16:4560627 T/A cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.81 0.4 4.35e-6 Schizophrenia; TGCT trans rs561341 0.660 rs7406043 chr17:30220152 C/G cg20587970 chr11:113659929 NA -0.8 -9.56 -0.65 1.44e-16 Hip circumference adjusted for BMI; TGCT cis rs3796352 1.000 rs71617204 chr3:53042951 G/A cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2153535 0.541 rs945304 chr6:8442892 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs7267979 1.000 rs7018 chr20:25278261 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg03517284 chr6:25882590 NA -0.92 -8.89 -0.62 6.09e-15 Intelligence (multi-trait analysis); TGCT cis rs1555895 0.576 rs4362075 chr10:865476 A/G cg02193355 chr10:851439 NA 0.2 4.55 0.38 1.28e-5 Survival in rectal cancer; TGCT cis rs4851266 0.898 rs12615145 chr2:100853116 C/T cg22139774 chr2:100720529 AFF3 -0.32 -4.66 -0.39 7.89e-6 Educational attainment; TGCT cis rs2228479 0.867 rs12930606 chr16:89946682 A/G cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs7666738 0.546 rs11727151 chr4:98837353 A/C cg18180107 chr4:99064573 C4orf37 0.58 5.02 0.41 1.75e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1577917 1.000 rs34281561 chr6:86701872 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg08859206 chr1:53392774 SCP2 -0.46 -7.42 -0.55 1.64e-11 Monocyte count; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg04234412 chr22:24373322 LOC391322 0.95 8.89 0.62 5.96e-15 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7831492 0.564 rs11787479 chr8:41613496 A/G cg17182837 chr8:41585554 ANK1 -0.18 -4.62 -0.38 9.31e-6 Colorectal cancer; TGCT cis rs3820068 0.608 rs12740492 chr1:16048951 A/T cg05660106 chr1:15850417 CASP9 0.73 6.71 0.52 6.18e-10 Systolic blood pressure; TGCT cis rs12200560 0.505 rs211165 chr6:97068520 A/T cg06623918 chr6:96969491 KIAA0776 0.57 4.83 0.4 3.93e-6 Coronary heart disease; TGCT cis rs9916302 0.904 rs2061338 chr17:37421767 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs17331151 0.573 rs4687556 chr3:52890475 T/C cg12962167 chr3:53033115 SFMBT1 -0.42 -4.83 -0.4 3.88e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6582630 0.615 rs10880642 chr12:38554152 A/G cg26384229 chr12:38710491 ALG10B -0.51 -4.73 -0.39 5.94e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs3749237 0.964 rs34522271 chr3:49808517 A/G cg07636037 chr3:49044803 WDR6 0.62 5.48 0.44 2.23e-7 Resting heart rate; TGCT cis rs11574514 1.000 rs79437914 chr16:67578143 C/A cg00545966 chr16:67701244 C16orf86;C16orf48 0.72 4.45 0.37 1.87e-5 Crohn's disease; TGCT trans rs2727020 0.521 rs10839296 chr11:49537617 T/C cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Coronary artery disease; TGCT cis rs7104764 0.957 rs1128321 chr11:244171 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs992157 0.687 rs35271699 chr2:219117482 G/A cg00012203 chr2:219082015 ARPC2 0.8 9.77 0.66 4.54e-17 Colorectal cancer; TGCT cis rs7914558 1.000 rs10883824 chr10:104812897 A/G cg15744005 chr10:104629667 AS3MT -0.37 -4.48 -0.37 1.64e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs875971 1.000 rs778685 chr7:65836176 G/T cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.11e-6 Aortic root size; TGCT cis rs9300255 0.537 rs2682429 chr12:123642955 C/G cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg13695892 chr22:41940480 POLR3H -0.91 -9.11 -0.63 1.82e-15 Vitiligo; TGCT cis rs3027234 0.723 rs11653623 chr17:8202620 G/C cg08322244 chr17:8066669 VAMP2 -0.56 -5.23 -0.43 6.87e-7 Telomere length; TGCT cis rs4654899 1.000 rs7525438 chr1:21458217 G/A cg01072550 chr1:21505969 NA -0.5 -8.07 -0.59 5.13e-13 Superior frontal gyrus grey matter volume; TGCT cis rs5769765 0.646 rs9616205 chr22:50309915 A/T cg15316289 chr22:50310904 ALG12;CRELD2 0.46 6.09 0.48 1.29e-8 Schizophrenia; TGCT cis rs782590 0.729 rs706548 chr2:55850106 C/G cg03859395 chr2:55845619 SMEK2 0.77 8.95 0.63 4.29e-15 Metabolic syndrome; TGCT trans rs11088226 0.681 rs8131384 chr21:33944127 C/T cg09050820 chr6:167586206 TCP10L2 0.82 7.4 0.55 1.8e-11 Gastritis; TGCT cis rs67073037 0.955 rs67873458 chr2:29119773 T/C cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs9902453 0.765 rs62068653 chr17:28212663 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.9 8.65 0.61 2.29e-14 Coffee consumption (cups per day); TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs35306767 0.903 rs7077278 chr10:911291 A/G cg26597838 chr10:835615 NA -0.74 -10.34 -0.68 1.86e-18 Eosinophil percentage of granulocytes; TGCT cis rs265548 0.608 rs265544 chr19:17903479 G/C cg21960279 chr19:17905606 B3GNT3 0.48 5.3 0.43 5.08e-7 Tumor biomarkers; TGCT cis rs9527 0.545 rs12247514 chr10:104958066 C/A cg04362960 chr10:104952993 NT5C2 0.68 5.73 0.46 7.14e-8 Arsenic metabolism; TGCT cis rs12142240 0.698 rs7548675 chr1:46809321 C/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs7772486 0.720 rs4896837 chr6:146014168 C/T cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2227564 0.620 rs3911887 chr10:75548026 A/G cg19442545 chr10:75533431 FUT11 -0.3 -4.48 -0.37 1.7e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11112613 0.713 rs2374502 chr12:105938939 T/C cg03607813 chr12:105948248 NA 0.44 5.36 0.43 3.85e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs6582630 0.555 rs2387598 chr12:38510472 G/A cg26384229 chr12:38710491 ALG10B -0.8 -7.43 -0.56 1.51e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs4700695 0.719 rs153390 chr5:65431087 G/C cg21114390 chr5:65439923 SFRS12 -0.88 -8.02 -0.58 6.82e-13 Facial morphology (factor 19); TGCT cis rs10782582 0.609 rs1689270 chr1:76390937 A/G cg03433033 chr1:76189801 ACADM -0.49 -4.81 -0.4 4.29e-6 Daytime sleep phenotypes; TGCT cis rs7312933 0.670 rs10880258 chr12:42547531 C/T cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7772486 0.790 rs9497435 chr6:146265340 C/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.21 0.82 2.06e-32 Prudent dietary pattern; TGCT cis rs12681287 0.752 rs12675974 chr8:87247845 T/C cg27223183 chr8:87520930 FAM82B -0.83 -5.76 -0.46 6.33e-8 Caudate activity during reward; TGCT cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.53 -4.96 -0.41 2.3e-6 Electroencephalogram traits; TGCT cis rs801193 1.000 rs2286684 chr7:66129830 G/T cg00343986 chr7:65444356 GUSB -0.23 -5.13 -0.42 1.07e-6 Aortic root size; TGCT cis rs8050907 0.744 rs7194436 chr16:4539832 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.58 4.65 0.39 8.46e-6 Obesity-related traits; TGCT cis rs4788570 0.609 rs72795869 chr16:71485515 C/T cg06353428 chr16:71660113 MARVELD3 -1.33 -7.91 -0.58 1.24e-12 Intelligence (multi-trait analysis); TGCT cis rs854765 0.583 rs62064158 chr17:17826935 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs9976767 0.637 rs2156309 chr21:43824529 G/A cg23042151 chr21:43824109 UBASH3A -0.23 -5.14 -0.42 1.02e-6 Type 1 diabetes; TGCT cis rs11105298 0.891 rs10777185 chr12:89921275 C/T cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg04546413 chr19:29218101 NA 0.84 6.76 0.52 4.71e-10 Methadone dose in opioid dependence; TGCT cis rs9911578 1.000 rs9901181 chr17:56964271 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.861 rs33933929 chr17:37426441 A/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs13082711 0.522 rs640065 chr3:27363937 A/T cg02860705 chr3:27208620 NA 0.29 4.63 0.38 9.02e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs8180040 0.726 rs7628747 chr3:47001990 A/T cg27129171 chr3:47204927 SETD2 0.73 9.51 0.65 1.94e-16 Colorectal cancer; TGCT cis rs7647973 1.000 rs11720542 chr3:49357427 A/G cg05785598 chr3:49045655 WDR6 0.39 4.62 0.38 9.58e-6 Menarche (age at onset); TGCT cis rs7552404 0.924 rs7535991 chr1:76162624 C/T cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6998277 1.000 rs6998277 chr8:103639941 T/C cg10187029 chr8:103597600 NA 0.45 5.6 0.45 1.32e-7 Migraine; TGCT cis rs10501293 0.703 rs7937503 chr11:43008602 G/C cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.2e-9 Cognitive performance; TGCT cis rs2832077 0.527 rs9980449 chr21:30224889 G/C cg24692254 chr21:30365293 RNF160 -0.59 -5.05 -0.41 1.53e-6 Cognitive test performance; TGCT cis rs72901758 0.768 rs55782477 chr17:76250703 G/C cg25512537 chr17:76250053 NA 0.25 4.51 0.38 1.49e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs6546537 0.911 rs13027712 chr2:69891367 C/T cg10773587 chr2:69614142 GFPT1 -0.82 -7.07 -0.54 1.01e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs7043114 0.525 rs7023004 chr9:95098712 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.56 -0.45 1.55e-7 Height; TGCT cis rs9926296 0.605 rs8046243 chr16:89852133 A/G cg26513180 chr16:89883248 FANCA 1.07 14.91 0.8 1.99e-29 Vitiligo; TGCT cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg02353165 chr6:42928485 GNMT 1.05 11.69 0.72 9.89e-22 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs763014 0.931 rs7191939 chr16:630089 C/T cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT trans rs877282 0.947 rs7904978 chr10:768078 C/T cg22713356 chr15:30763199 NA 1.19 9.85 0.66 2.99e-17 Uric acid levels; TGCT cis rs4285028 0.948 rs79103597 chr3:121667629 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs9303401 0.659 rs11079357 chr17:56902778 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs5769707 0.967 rs8141807 chr22:50043738 C/G cg05373962 chr22:49881684 NA -0.31 -6.42 -0.5 2.6e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs826838 1.000 rs11183747 chr12:38822595 A/G cg13010199 chr12:38710504 ALG10B -0.77 -6.42 -0.5 2.63e-9 Heart rate; TGCT cis rs7552404 0.727 rs1146653 chr1:76280438 A/G cg03433033 chr1:76189801 ACADM 0.66 6.9 0.53 2.36e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs644799 1.000 rs560854 chr11:95584905 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.67 0.69 2.95e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11030122 0.702 rs10835399 chr11:3989182 G/A cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs939574 0.790 rs72955439 chr2:220090804 T/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.11 5.34 0.43 4.31e-7 Platelet distribution width; TGCT cis rs4927850 0.881 rs7630489 chr3:195753401 T/C cg02975922 chr3:195473998 MUC4 -0.24 -5.47 -0.44 2.4e-7 Pancreatic cancer; TGCT cis rs796364 0.715 rs78988795 chr2:201095739 G/A cg17644776 chr2:200775616 C2orf69 -0.39 -5.16 -0.42 9.43e-7 Schizophrenia; TGCT cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg08645402 chr16:4508243 NA 0.2 5.02 0.41 1.73e-6 Schizophrenia; TGCT cis rs7914558 1.000 rs7077291 chr10:104945751 C/T cg15744005 chr10:104629667 AS3MT -0.39 -4.73 -0.39 5.91e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2797160 1.000 rs4895798 chr6:126000162 A/G cg05901451 chr6:126070800 HEY2 -0.74 -6.48 -0.5 1.96e-9 Endometrial cancer; TGCT cis rs7572733 0.534 rs4850815 chr2:198786167 G/T cg00792783 chr2:198669748 PLCL1 -0.57 -5.14 -0.42 1.03e-6 Dermatomyositis; TGCT cis rs36051895 0.622 rs12686652 chr9:5071942 C/G cg02405213 chr9:5042618 JAK2 -0.76 -9.95 -0.67 1.69e-17 Pediatric autoimmune diseases; TGCT cis rs9807841 0.670 rs1982075 chr19:10787744 C/G cg17848348 chr19:10766748 ILF3 -0.4 -4.58 -0.38 1.12e-5 Inflammatory skin disease; TGCT cis rs12908161 1.000 rs58416181 chr15:85264461 G/A cg17173187 chr15:85201210 NMB 0.59 6.77 0.52 4.55e-10 Schizophrenia; TGCT cis rs8078723 1.000 rs3826331 chr17:38150492 T/C cg17467752 chr17:38218738 THRA -0.57 -5.5 -0.44 2.04e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs2997447 0.761 rs61776576 chr1:26429898 G/A cg03844060 chr1:26490628 NA 0.27 4.47 0.37 1.76e-5 QRS complex (12-leadsum); TGCT cis rs6681544 0.544 rs1492258 chr1:82395964 A/G cg04226724 chr1:82268649 LPHN2 0.47 4.99 0.41 2.02e-6 Metabolite levels (X-11787); TGCT cis rs1801251 0.896 rs79793315 chr2:233690864 C/T cg25237894 chr2:233734115 C2orf82 -0.29 -5.41 -0.44 3.14e-7 Coronary artery disease; TGCT cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.64 -6.18 -0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs2708977 0.637 rs679414 chr2:97087788 A/C cg01950434 chr2:97203154 ARID5A -0.61 -5.19 -0.42 8.42e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg23758822 chr17:41437982 NA 0.72 6.91 0.53 2.23e-10 Menopause (age at onset); TGCT cis rs17152411 1.000 rs11245451 chr10:126661428 C/T cg07906193 chr10:126599966 NA 0.39 4.53 0.38 1.35e-5 Height; TGCT cis rs6570726 0.818 rs399516 chr6:145810849 C/A cg23711669 chr6:146136114 FBXO30 0.76 7.62 0.56 5.74e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs13088645 0.532 rs9851770 chr3:134160593 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.68 6.22 0.49 6.96e-9 Coronary artery disease; TGCT cis rs1348850 0.608 rs2364845 chr2:178226240 T/C cg22681709 chr2:178499509 PDE11A -0.35 -4.54 -0.38 1.3e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs875971 0.660 rs10215132 chr7:66054406 C/A cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.08e-7 Aortic root size; TGCT trans rs4332037 0.539 rs56305291 chr7:2048706 A/G cg10840412 chr1:235813424 GNG4 0.92 6.66 0.51 8e-10 Bipolar disorder; TGCT cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg17554472 chr22:41940697 POLR3H -0.52 -5.37 -0.43 3.79e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg10150615 chr22:24372951 LOC391322 -0.78 -8.72 -0.62 1.56e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs174601 0.861 rs174584 chr11:61610750 G/A cg19610905 chr11:61596333 FADS2 -0.88 -8.16 -0.59 3.2e-13 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs769267 0.931 rs2965193 chr19:19454828 G/A cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs1670533 0.932 rs13140341 chr4:1054235 T/C cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs3859192 0.561 rs12453343 chr17:38181176 C/A cg17467752 chr17:38218738 THRA -0.52 -4.59 -0.38 1.09e-5 White blood cell count; TGCT cis rs9372498 0.908 rs17080082 chr6:118700137 C/T cg18833306 chr6:118973337 C6orf204 -0.61 -4.81 -0.4 4.28e-6 Diastolic blood pressure; TGCT cis rs7772486 0.686 rs9399565 chr6:146081906 G/T cg23711669 chr6:146136114 FBXO30 -0.89 -9.88 -0.66 2.48e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs11864453 0.614 rs12445586 chr16:72126276 C/T cg14768367 chr16:72042858 DHODH 0.51 4.82 0.4 4.06e-6 Fibrinogen levels; TGCT cis rs7089973 0.604 rs10885620 chr10:116630048 A/T cg03647239 chr10:116582469 FAM160B1 0.58 5.48 0.44 2.29e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs950027 0.620 rs1145084 chr15:45675440 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 6.04 0.48 1.7e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs17331151 0.505 rs13066389 chr3:52565317 C/T cg07884673 chr3:53033167 SFMBT1 0.74 4.99 0.41 1.98e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3784262 0.565 rs3784264 chr15:58250246 T/G cg12031962 chr15:58353849 ALDH1A2 0.37 5.17 0.42 8.99e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs10782582 0.593 rs6664254 chr1:76235084 G/T cg03433033 chr1:76189801 ACADM -0.55 -6.05 -0.48 1.61e-8 Daytime sleep phenotypes; TGCT cis rs77972916 0.609 rs13414381 chr2:43567218 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -4.83 -0.4 4e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs986417 0.901 rs1955687 chr14:60988606 A/G cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs7020830 0.571 rs3780335 chr9:37376587 A/G cg14294708 chr9:37120828 ZCCHC7 -0.94 -8.94 -0.63 4.48e-15 Schizophrenia; TGCT cis rs62064224 0.614 rs6505294 chr17:30687415 C/T cg18200150 chr17:30822561 MYO1D 0.4 4.73 0.39 6.05e-6 Schizophrenia; TGCT cis rs7552404 1.000 rs12123977 chr1:76209754 A/G cg22875332 chr1:76189707 ACADM -0.88 -7.44 -0.56 1.48e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2404602 0.967 rs7174096 chr15:77072400 A/G cg22467129 chr15:76604101 ETFA -0.46 -5.04 -0.41 1.58e-6 Blood metabolite levels; TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg21226059 chr5:178986404 RUFY1 0.63 7.74 0.57 2.98e-12 Lung cancer; TGCT cis rs6951245 0.554 rs10270249 chr7:1151886 G/T cg03188948 chr7:1209495 NA 0.5 5.23 0.43 6.99e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2153535 0.580 rs1414344 chr6:8471365 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT trans rs561341 1.000 rs555629 chr17:30294136 T/C cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT trans rs208520 0.955 rs208538 chr6:66964492 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.87 -8.1 -0.59 4.41e-13 Exhaled nitric oxide output; TGCT cis rs425277 0.958 rs7546523 chr1:2043792 G/A cg24578937 chr1:2090814 PRKCZ 0.3 6.88 0.53 2.61e-10 Height; TGCT cis rs7119 0.651 rs12917044 chr15:77850146 A/G cg27398640 chr15:77910606 LINGO1 0.27 5.09 0.42 1.32e-6 Type 2 diabetes; TGCT cis rs6671200 0.607 rs3767313 chr1:95712797 G/A cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs6952808 0.609 rs11772205 chr7:1951236 C/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.44 -0.37 1.95e-5 Bipolar disorder and schizophrenia; TGCT cis rs7223966 0.961 rs17631394 chr17:61646000 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.57 -4.64 -0.38 8.68e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7567389 0.564 rs10209483 chr2:128158637 C/T cg09760422 chr2:128146352 NA -0.38 -4.93 -0.41 2.54e-6 Self-rated health; TGCT cis rs2180341 0.961 rs3798857 chr6:127659473 A/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs57221529 0.766 rs28563961 chr5:554498 C/G cg09021430 chr5:549028 NA -0.41 -5.48 -0.44 2.23e-7 Lung disease severity in cystic fibrosis; TGCT cis rs3617 0.625 rs56019197 chr3:52874753 T/C cg10802521 chr3:52805072 NEK4 0.62 7.18 0.54 5.66e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs554111 0.571 rs4537519 chr1:21461370 T/C cg01072550 chr1:21505969 NA 0.37 5.56 0.45 1.56e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs9393692 0.905 rs7746807 chr6:26293338 C/A cg13736514 chr6:26305472 NA -0.39 -5.65 -0.45 1.04e-7 Educational attainment; TGCT cis rs7017914 0.905 rs4504667 chr8:71956792 C/T cg23757474 chr8:71581111 LACTB2;XKR9 0.55 5.11 0.42 1.17e-6 Bone mineral density; TGCT cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.05 0.41 1.51e-6 Menopause (age at onset); TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg02953382 chr22:24373134 LOC391322 0.8 6.87 0.53 2.77e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9611565 0.512 rs1983576 chr22:42166486 G/A cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs42648 0.935 rs42664 chr7:89984409 A/G cg25739043 chr7:89950458 NA -0.65 -6.22 -0.49 6.96e-9 Homocysteine levels; TGCT cis rs6815814 0.699 rs11730390 chr4:38881414 T/C cg02016764 chr4:38805732 TLR1 -0.34 -5.08 -0.41 1.37e-6 Breast cancer; TGCT cis rs1153858 1.000 rs7164602 chr15:45671325 A/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs2439831 0.867 rs2243434 chr15:43689867 A/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.14 0.59 3.58e-13 Lung cancer in ever smokers; TGCT cis rs7666738 0.791 rs1967978 chr4:98966152 T/C cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.900 rs10019460 chr4:17686337 T/C cg16339924 chr4:17578868 LAP3 -0.6 -4.87 -0.4 3.34e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11209002 0.614 rs7544189 chr1:67568351 C/T cg02640540 chr1:67518911 SLC35D1 0.59 4.97 0.41 2.18e-6 Crohn's disease; TGCT cis rs35883536 0.587 rs2809812 chr1:101032087 G/T cg06223162 chr1:101003688 GPR88 0.42 8.32 0.6 1.36e-13 Monocyte count; TGCT cis rs1372520 0.577 rs748849 chr4:90734961 G/A cg01966878 chr4:90757139 SNCA -0.31 -4.91 -0.4 2.85e-6 Neuroticism; TGCT cis rs782590 0.582 rs2627767 chr2:55926815 A/T cg18811423 chr2:55921094 PNPT1 0.56 5.56 0.45 1.54e-7 Metabolic syndrome; TGCT cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs62103177 0.608 rs59300126 chr18:77694439 C/A cg12964065 chr18:77638022 KCNG2 0.34 4.83 0.4 3.91e-6 Opioid sensitivity; TGCT cis rs4819052 0.851 rs2838865 chr21:46712299 C/T cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs72627509 1.000 rs57265257 chr4:57839280 A/T cg26694713 chr4:57773883 REST 0.74 6.45 0.5 2.3e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1055129 0.537 rs2467100 chr17:73949038 C/G cg10935138 chr17:73851978 WBP2 0.51 4.6 0.38 1.01e-5 White matter hyperintensity burden; TGCT cis rs9894429 0.789 rs6565611 chr17:79598319 T/C cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs8180040 0.903 rs11130124 chr3:47292183 T/C cg27129171 chr3:47204927 SETD2 0.71 8.58 0.61 3.22e-14 Colorectal cancer; TGCT cis rs4595586 0.545 rs7136002 chr12:39369168 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs28489187 0.617 rs7547571 chr1:85884091 G/T cg16011679 chr1:85725395 C1orf52 -0.48 -4.45 -0.37 1.91e-5 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg16145915 chr7:1198662 ZFAND2A -0.54 -7.02 -0.53 1.27e-10 Longevity;Endometriosis; TGCT cis rs12134133 1.000 rs7526831 chr1:207438606 G/C cg02152968 chr1:207494213 CD55 0.64 4.78 0.39 4.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs3015497 0.526 rs10136630 chr14:51046474 G/A cg04730355 chr14:51134070 SAV1 -0.64 -6.18 -0.49 8.59e-9 Mean platelet volume; TGCT cis rs6831352 0.840 rs29001223 chr4:100047433 C/T cg12011299 chr4:100065546 ADH4 -0.44 -5.06 -0.41 1.45e-6 Alcohol dependence; TGCT cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs9311474 0.607 rs4234633 chr3:52557038 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.91 0.4 2.75e-6 Electroencephalogram traits; TGCT cis rs2730245 1.000 rs6965685 chr7:158726462 C/T cg24397884 chr7:158709396 WDR60 0.39 5.13 0.42 1.07e-6 Height; TGCT cis rs12497850 0.897 rs6795025 chr3:49081247 T/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 3e-7 Parkinson's disease; TGCT cis rs7833790 0.929 rs10958048 chr8:82792914 C/T cg17211192 chr8:82754475 SNX16 0.95 7.32 0.55 2.79e-11 Diastolic blood pressure; TGCT cis rs72627509 0.629 rs1718824 chr4:57903747 A/C cg26694713 chr4:57773883 REST -0.59 -4.85 -0.4 3.57e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs911263 0.603 rs12881502 chr14:68783791 A/C cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs7246657 0.722 rs10410588 chr19:38042410 C/G cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs9549367 0.577 rs513479 chr13:113815200 C/T cg18105134 chr13:113819100 PROZ -0.46 -7.48 -0.56 1.18e-11 Platelet distribution width; TGCT cis rs7666738 0.830 rs1426664 chr4:98988264 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4409675 0.576 rs6703851 chr1:28237556 G/A cg23691781 chr1:28212827 C1orf38 0.27 5.61 0.45 1.24e-7 Corneal astigmatism; TGCT cis rs7264396 0.635 rs6121102 chr20:34544274 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs9787249 0.874 rs12094291 chr1:40226046 G/A cg24920358 chr1:40204285 PPIE 0.58 10.69 0.69 2.69e-19 Blood protein levels; TGCT cis rs4713118 0.662 rs149961 chr6:28015569 A/C cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs986417 0.792 rs4901990 chr14:61015474 C/T cg27398547 chr14:60952738 C14orf39 -1.37 -8.5 -0.61 5.08e-14 Gut microbiota (bacterial taxa); TGCT cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg03452623 chr4:187889614 NA -0.36 -5.46 -0.44 2.45e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.652 rs488363 chr11:68658298 C/G cg21963583 chr11:68658836 MRPL21 0.36 6.08 0.48 1.35e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10782582 0.609 rs5745543 chr1:76365111 A/T cg03433033 chr1:76189801 ACADM -0.5 -4.92 -0.4 2.7e-6 Daytime sleep phenotypes; TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs1008375 1.000 rs4698648 chr4:17692715 C/G cg18681998 chr4:17616180 MED28 0.76 7.28 0.55 3.42e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6690583 0.573 rs61768854 chr1:85460021 T/C cg20280350 chr1:85513789 MCOLN3 -0.78 -5.19 -0.42 8.21e-7 Serum sulfate level; TGCT cis rs6840360 0.904 rs6825241 chr4:152543783 C/A cg17479576 chr4:152424074 FAM160A1 -0.53 -5.85 -0.46 4.14e-8 Intelligence (multi-trait analysis); TGCT cis rs6061231 0.740 rs11698650 chr20:60958374 A/T cg15674680 chr20:60982522 CABLES2 0.5 4.47 0.37 1.74e-5 Colorectal cancer; TGCT cis rs7014346 0.767 rs7013328 chr8:128423911 G/A cg04263511 chr8:128962092 PVT1 -0.31 -4.5 -0.37 1.54e-5 Colorectal cancer; TGCT cis rs2458413 0.542 rs1810113 chr8:105364594 C/T cg04554929 chr8:105342491 NA -0.47 -5.7 -0.46 8.11e-8 Paget's disease; TGCT cis rs2204008 0.837 rs1589395 chr12:38420405 C/T cg13010199 chr12:38710504 ALG10B 0.59 4.79 0.4 4.67e-6 Bladder cancer; TGCT cis rs6121246 0.559 rs6058468 chr20:30406448 C/A cg18721089 chr20:30220636 NA -0.35 -4.5 -0.37 1.58e-5 Mean corpuscular hemoglobin; TGCT cis rs2073300 1.000 rs12625804 chr20:23441981 G/A cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7666738 0.830 rs10007261 chr4:98926155 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7809950 0.635 rs62483629 chr7:106866178 T/C cg23024343 chr7:107201750 COG5 -0.43 -5.91 -0.47 3.13e-8 Coronary artery disease; TGCT cis rs7805747 0.961 rs10224002 chr7:151415041 C/T cg17611936 chr7:151411526 PRKAG2 -0.54 -7.09 -0.54 8.88e-11 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs17376456 0.825 rs13164315 chr5:93147421 A/G cg21475434 chr5:93447410 FAM172A 0.62 4.67 0.39 7.58e-6 Diabetic retinopathy; TGCT cis rs61472021 1 rs61472021 chr6:26090025 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.56 -4.52 -0.38 1.43e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.800 rs13107586 chr4:99028788 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs3852123 chr4:98697586 A/G cg18180107 chr4:99064573 C4orf37 0.56 5.32 0.43 4.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2982552 0.873 rs1415194 chr6:152063998 A/G cg22157087 chr6:152012887 ESR1 0.21 4.92 0.4 2.65e-6 Bone properties (heel); TGCT cis rs76878669 0.561 rs6591215 chr11:66170611 A/C cg18002602 chr11:66138449 SLC29A2 -0.52 -6.38 -0.5 3.21e-9 Educational attainment (years of education); TGCT cis rs2832191 0.679 rs2705659 chr21:30363908 G/C cg08807101 chr21:30365312 RNF160 0.64 6.05 0.48 1.57e-8 Dental caries; TGCT cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg10465839 chr16:1584050 IFT140;TMEM204 -0.32 -5.23 -0.43 6.98e-7 Coronary artery disease; TGCT cis rs2862064 0.745 rs2902133 chr5:156445687 G/A cg12943317 chr5:156479607 HAVCR1 -0.38 -5.2 -0.42 8.06e-7 Platelet count; TGCT cis rs308403 0.568 rs13146929 chr4:123671151 C/G cg10495464 chr4:123653540 BBS12;LOC729338 0.7 6.51 0.5 1.66e-9 Blood protein levels; TGCT cis rs4242434 0.597 rs876714 chr8:22482799 A/G cg03733263 chr8:22462867 KIAA1967 0.98 13.34 0.77 1.01e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs6840360 0.571 rs10007653 chr4:152524055 A/G cg17479576 chr4:152424074 FAM160A1 -0.68 -7.2 -0.54 5.05e-11 Intelligence (multi-trait analysis); TGCT cis rs7017914 0.967 rs56112621 chr8:71588394 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs319204 0.918 rs547882 chr5:146288069 A/C cg25021259 chr5:146258546 PPP2R2B -0.36 -4.56 -0.38 1.19e-5 Schizophrenia; TGCT cis rs350251 0.868 rs350231 chr16:12186376 T/G cg02910054 chr16:12241554 SNX29 0.35 4.54 0.38 1.29e-5 Intelligence (multi-trait analysis); TGCT cis rs7586879 0.681 rs6705446 chr2:25118608 T/C cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs7617773 0.817 rs13068265 chr3:48301614 A/C cg11946769 chr3:48343235 NME6 0.76 6.63 0.51 9.31e-10 Coronary artery disease; TGCT cis rs727563 0.580 rs202626 chr22:41847190 C/A cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Crohn's disease;Inflammatory bowel disease; TGCT cis rs922182 0.633 rs12904468 chr15:64268890 A/T cg02919090 chr15:64263738 DAPK2 -0.29 -5.08 -0.42 1.33e-6 Blood protein levels; TGCT cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg17554472 chr22:41940697 POLR3H -0.49 -5.26 -0.43 6.14e-7 Vitiligo; TGCT cis rs10514758 0.744 rs72947749 chr3:114927068 C/A cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs57994353 0.568 rs10870166 chr9:139316916 C/G cg13741927 chr9:139327495 INPP5E -0.24 -5.35 -0.43 4.07e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT trans rs6089829 0.926 rs6062395 chr20:61667904 A/G cg13615516 chr5:77269221 NA 0.65 8.04 0.59 6.2e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1847202 0.859 rs13096870 chr3:72948172 G/A cg25664220 chr3:72788482 NA -0.36 -4.48 -0.37 1.69e-5 Motion sickness; TGCT cis rs9486715 0.838 rs4839840 chr6:96941149 T/C cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs9549367 0.789 rs3764124 chr13:113897320 C/T cg18105134 chr13:113819100 PROZ -0.35 -5.96 -0.47 2.43e-8 Platelet distribution width; TGCT cis rs6121246 0.559 rs1484994 chr20:30305975 A/G cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg04944784 chr2:26401820 FAM59B -0.77 -6.37 -0.5 3.27e-9 Gut microbiome composition (summer); TGCT cis rs6684514 0.961 rs10908503 chr1:156300683 C/T cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs72615157 0.634 rs2272343 chr7:99778285 A/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.61 4.99 0.41 1.98e-6 Lung function (FEV1/FVC); TGCT cis rs6912958 0.703 rs9362427 chr6:88097634 G/T cg08069147 chr6:88032118 GJB7;C6orf162 0.62 6.09 0.48 1.29e-8 Monocyte percentage of white cells; TGCT cis rs12765878 1.000 rs1980653 chr10:105654164 A/G cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs13256369 1.000 rs10110591 chr8:8576608 G/T cg18904891 chr8:8559673 CLDN23 -0.62 -5.68 -0.45 9.21e-8 Obesity-related traits; TGCT cis rs7267979 0.966 rs2261698 chr20:25259910 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9527 0.614 rs11191589 chr10:104930382 T/C cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.07e-7 Arsenic metabolism; TGCT cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg03264133 chr6:25882463 NA 0.49 5.23 0.42 7.04e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs10012003 chr4:99064881 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.31 0.43 4.87e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3806843 0.966 rs2240693 chr5:140183325 G/C cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs12681288 0.782 rs2600499 chr8:1026619 C/T cg04851639 chr8:1020857 NA -0.34 -6.07 -0.48 1.44e-8 Schizophrenia; TGCT cis rs7584330 0.554 rs7573177 chr2:238444467 C/T cg08992911 chr2:238395768 MLPH -0.66 -4.62 -0.38 9.28e-6 Prostate cancer; TGCT cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg07636037 chr3:49044803 WDR6 0.88 9.28 0.64 6.89e-16 Menarche (age at onset); TGCT cis rs6088580 0.634 rs62212172 chr20:32987705 G/A cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT trans rs17780086 0.527 rs72827711 chr17:30537920 T/A cg20587970 chr11:113659929 NA -0.89 -7.15 -0.54 6.46e-11 Height; TGCT cis rs514406 0.825 rs497535 chr1:53284677 A/G cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs7954584 0.567 rs1169071 chr12:122390084 G/T cg21016266 chr12:122356598 WDR66 0.54 7.02 0.53 1.26e-10 Mean corpuscular volume; TGCT cis rs7147624 0.882 rs1956008 chr14:66085429 G/T cg03016385 chr14:66212404 NA -0.49 -7.08 -0.54 9.33e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9894429 0.690 rs12949956 chr17:79542813 C/T cg18240062 chr17:79603768 NPLOC4 -0.85 -10.0 -0.67 1.28e-17 Eye color traits; TGCT cis rs17253792 0.822 rs78143160 chr14:56150097 A/G cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs11030122 0.702 rs66503725 chr11:3980998 G/A cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs9325144 0.647 rs12831609 chr12:39051576 C/A cg26384229 chr12:38710491 ALG10B -0.56 -5.1 -0.42 1.25e-6 Morning vs. evening chronotype; TGCT cis rs7226408 0.857 rs55917307 chr18:34503664 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6740731 0.518 rs34586719 chr2:145295647 C/T cg07679370 chr2:145795797 NA 0.29 5.63 0.45 1.14e-7 Coronary artery disease; TGCT cis rs11249608 0.548 rs7707587 chr5:178462590 G/C cg01312482 chr5:178451176 ZNF879 -0.49 -4.83 -0.4 3.96e-6 Pubertal anthropometrics; TGCT trans rs9951602 0.512 rs8097996 chr18:76648035 A/G cg02800362 chr5:177631904 HNRNPAB 1.15 12.91 0.76 1.08e-24 Obesity-related traits; TGCT trans rs17685 0.702 rs6960598 chr7:75772991 T/C cg19862616 chr7:65841803 NCRNA00174 0.53 9.19 0.64 1.13e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs981844 0.775 rs17371468 chr4:154759826 G/C cg14289246 chr4:154710475 SFRP2 1.01 8.89 0.62 5.85e-15 Response to statins (LDL cholesterol change); TGCT cis rs5750830 0.649 rs4821893 chr22:39797779 G/A cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.541 rs56055826 chr4:119789424 T/A cg21605333 chr4:119757512 SEC24D 1.55 8.04 0.59 6.15e-13 Cannabis dependence symptom count; TGCT trans rs561341 0.714 rs474455 chr17:30312465 A/T cg20587970 chr11:113659929 NA -1.05 -12.74 -0.75 2.84e-24 Hip circumference adjusted for BMI; TGCT cis rs11031096 0.754 rs10742242 chr11:4156851 T/C cg18678763 chr11:4115507 RRM1 -0.46 -5.87 -0.47 3.74e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs644799 0.544 rs499637 chr11:95569183 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.57 5.84 0.46 4.36e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6952808 0.760 rs11764960 chr7:1950532 G/A cg22963979 chr7:1858916 MAD1L1 -0.34 -5.13 -0.42 1.08e-6 Bipolar disorder and schizophrenia; TGCT cis rs7524258 0.900 rs6689574 chr1:7288534 C/G cg07173049 chr1:7289937 CAMTA1 0.28 4.68 0.39 7.24e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs7582180 0.614 rs1530030 chr2:101009600 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.77 0.39 5.18e-6 Intelligence (multi-trait analysis); TGCT cis rs12908161 0.960 rs62019463 chr15:85288087 G/A cg11189052 chr15:85197271 WDR73 0.7 5.76 0.46 6.18e-8 Schizophrenia; TGCT cis rs7104764 0.917 rs7107362 chr11:244108 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs1862618 0.671 rs2591958 chr5:56239369 C/G cg24531977 chr5:56204891 C5orf35 0.68 7.22 0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs6952808 0.575 rs10280993 chr7:1948096 T/C cg04267008 chr7:1944627 MAD1L1 -0.37 -4.83 -0.4 3.94e-6 Bipolar disorder and schizophrenia; TGCT cis rs1005277 0.579 rs1780146 chr10:38517874 C/A cg25427524 chr10:38739819 LOC399744 -0.4 -8.32 -0.6 1.33e-13 Extrinsic epigenetic age acceleration; TGCT cis rs11148252 0.774 rs7334583 chr13:52930352 G/T cg02158880 chr13:53174818 NA -0.38 -4.51 -0.38 1.5e-5 Lewy body disease; TGCT cis rs9916302 0.784 rs4795382 chr17:37700860 A/G cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs3125734 0.633 rs4979774 chr10:63967795 A/T cg19640130 chr10:64028056 RTKN2 -0.4 -5.2 -0.42 8e-7 Rheumatoid arthritis; TGCT cis rs1670533 1.000 rs4690213 chr4:1054868 C/T cg20887711 chr4:1340912 KIAA1530 0.69 5.48 0.44 2.32e-7 Recombination rate (females); TGCT cis rs875971 0.862 rs3893216 chr7:65790707 G/C cg11764359 chr7:65958608 NA -0.55 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs4808199 0.895 rs10403731 chr19:19469296 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.65 4.79 0.39 4.73e-6 Nonalcoholic fatty liver disease; TGCT cis rs7772486 0.840 rs854144 chr6:146360880 G/T cg05347473 chr6:146136440 FBXO30 -0.54 -5.1 -0.42 1.26e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg01411255 chr17:61851458 DDX42;CCDC47 1.04 11.52 0.72 2.57e-21 Height; TGCT cis rs4900538 0.819 rs72698595 chr14:102863099 G/A cg18135206 chr14:102964638 TECPR2 -0.2 -4.49 -0.37 1.6e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.31 0.55 2.94e-11 Prudent dietary pattern; TGCT cis rs12701220 0.894 rs13224488 chr7:1052353 C/A cg07217954 chr7:1067459 C7orf50 -0.49 -4.76 -0.39 5.27e-6 Bronchopulmonary dysplasia; TGCT cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg10802521 chr3:52805072 NEK4 -0.7 -8.75 -0.62 1.28e-14 Bipolar disorder; TGCT cis rs7698623 0.850 rs4693194 chr4:88798005 T/C cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs1008375 1.000 rs6818639 chr4:17633049 A/G cg10189774 chr4:17578691 LAP3 0.62 5.5 0.44 2.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3820068 0.581 rs16851819 chr1:15918739 C/T cg05660106 chr1:15850417 CASP9 -0.76 -7.46 -0.56 1.35e-11 Systolic blood pressure; TGCT cis rs7568458 0.905 rs6714709 chr2:85756375 C/G cg17127132 chr2:85788382 GGCX 0.73 6.98 0.53 1.59e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs8013055 0.846 rs10136015 chr14:105973469 A/C cg25008857 chr14:105974488 NA 0.27 4.65 0.39 8.35e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs950880 0.560 rs10189711 chr2:102930881 A/G cg09003973 chr2:102972529 NA -0.53 -4.71 -0.39 6.47e-6 Serum protein levels (sST2); TGCT cis rs7224685 0.569 rs8082425 chr17:3991706 C/G cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs3008870 0.583 rs11208978 chr1:67442210 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.97 -8.16 -0.59 3.17e-13 Lymphocyte percentage of white cells; TGCT cis rs3087591 0.708 rs2525574 chr17:29705947 T/C cg24425628 chr17:29625626 OMG;NF1 0.41 5.93 0.47 2.87e-8 Hip circumference; TGCT cis rs6809651 0.524 rs56940353 chr3:185798296 T/C cg00760338 chr3:185826511 ETV5 -0.68 -5.05 -0.41 1.51e-6 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs7614311 0.555 rs3774715 chr3:63919876 T/C cg22134162 chr3:63841271 THOC7 -0.49 -6.29 -0.49 4.93e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs12643440 0.538 rs56235875 chr4:17138883 T/C cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.962 rs1116450 chr20:61658210 T/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs11578119 0.933 rs12135132 chr1:170493630 A/T cg09767346 chr1:170501363 GORAB 0.65 5.26 0.43 6.06e-7 Male-pattern baldness; TGCT cis rs295140 0.535 rs2033804 chr2:201222403 A/T cg04283868 chr2:201171347 SPATS2L 0.58 5.8 0.46 5.13e-8 QT interval; TGCT cis rs78456975 0.506 rs13402886 chr2:1575348 G/A cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs57994353 0.897 rs12551527 chr9:139358425 C/G cg13741927 chr9:139327495 INPP5E -0.26 -5.95 -0.47 2.51e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs56104184 0.779 rs17272666 chr19:49356294 T/C cg21252483 chr19:49399788 TULP2 -0.36 -4.65 -0.39 8.27e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6546537 1.000 rs3899666 chr2:69867871 A/G cg10773587 chr2:69614142 GFPT1 0.6 4.96 0.41 2.24e-6 Serum thyroid-stimulating hormone levels; TGCT cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg22166914 chr1:53195759 ZYG11B -0.39 -6.57 -0.51 1.25e-9 Monocyte count; TGCT cis rs4665809 0.549 rs72809635 chr2:26411674 G/A cg22920501 chr2:26401640 FAM59B 0.81 5.39 0.44 3.37e-7 Gut microbiome composition (summer); TGCT cis rs13064411 0.696 rs6768648 chr3:113234141 C/G cg18753928 chr3:113234510 CCDC52 -0.7 -5.64 -0.45 1.07e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7179456 0.557 rs446126 chr15:59113102 A/G cg05156742 chr15:59063176 FAM63B 0.56 5.25 0.43 6.3e-7 Asperger disorder; TGCT cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9916302 0.653 rs11657058 chr17:37699378 T/G cg03321784 chr17:37729644 NA 0.44 4.58 0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs9911578 1.000 rs2079703 chr17:56603978 G/A cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.658 rs10974910 chr9:5010091 G/A cg02405213 chr9:5042618 JAK2 -0.75 -10.06 -0.67 8.84e-18 Pediatric autoimmune diseases; TGCT cis rs8177253 0.965 rs8177260 chr3:133480458 T/A cg11941060 chr3:133502564 NA -0.3 -6.3 -0.49 4.78e-9 Iron status biomarkers; TGCT cis rs2762353 0.574 rs9467570 chr6:25699283 C/A cg03264133 chr6:25882463 NA 0.89 8.91 0.62 5.33e-15 Blood metabolite levels; TGCT cis rs709400 0.663 rs11626787 chr14:103991749 A/G cg26031613 chr14:104095156 KLC1 0.88 9.39 0.64 3.88e-16 Body mass index; TGCT cis rs9467773 1.000 rs1884949 chr6:26568067 G/A cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT trans rs551517 0.541 rs491855 chr9:113638739 T/C cg18410444 chr5:89825535 LYSMD3 0.69 6.98 0.53 1.55e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs11785400 0.793 rs7459963 chr8:143737129 C/T cg10596483 chr8:143751796 JRK 0.57 5.64 0.45 1.11e-7 Schizophrenia; TGCT cis rs8033133 0.957 rs3742952 chr15:25351026 A/G cg14481604 chr15:25334117 SNORD116-22 -0.3 -6.15 -0.48 9.95e-9 Blood osmolality (transformed sodium); TGCT cis rs3820928 0.874 rs6717168 chr2:227901342 C/T cg11843606 chr2:227700838 RHBDD1 -0.53 -4.78 -0.39 4.8e-6 Pulmonary function; TGCT cis rs10465746 0.967 rs942849 chr1:84427499 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs6693567 0.545 rs4970922 chr1:150458094 C/A cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Migraine; TGCT cis rs10883723 0.775 rs7917158 chr10:104246471 C/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7829975 0.748 rs693109 chr8:8640172 C/A cg06636001 chr8:8085503 FLJ10661 -0.65 -5.5 -0.44 2.07e-7 Mood instability; TGCT cis rs13191362 1.000 rs35820211 chr6:163046252 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.92 7.24 0.55 4.11e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs79349575 0.749 rs2546491 chr17:46977916 A/G cg07967210 chr17:47022446 SNF8 0.43 6.08 0.48 1.4e-8 Type 2 diabetes; TGCT cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg16497277 chr3:49208875 KLHDC8B -0.55 -5.26 -0.43 6.09e-7 Menarche (age at onset); TGCT cis rs5769707 0.967 rs12485195 chr22:50053871 G/A cg10356904 chr22:49881777 NA -0.23 -4.6 -0.38 1.02e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4665809 1.000 rs7588802 chr2:26277789 A/G cg27170947 chr2:26402098 FAM59B -0.4 -4.58 -0.38 1.1e-5 Gut microbiome composition (summer); TGCT cis rs7666738 0.791 rs2865958 chr4:99040732 G/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12908161 1.000 rs17600551 chr15:85319258 A/G cg12863693 chr15:85201151 NMB 0.43 5.12 0.42 1.15e-6 Schizophrenia; TGCT cis rs12908161 1.000 rs12908549 chr15:85322351 C/G cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.04e-8 Schizophrenia; TGCT cis rs877282 1.000 rs12219807 chr10:772870 A/C cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs910316 0.687 rs11627442 chr14:75669649 A/G cg08847533 chr14:75593920 NEK9 -0.81 -7.71 -0.57 3.55e-12 Height; TGCT cis rs877282 0.797 rs7079164 chr10:756363 A/G cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs11043280 0.703 rs11043275 chr12:122402723 T/C cg21171335 chr12:122356390 WDR66 0.64 6.54 0.51 1.41e-9 Mean platelet volume; TGCT cis rs950169 0.922 rs67804993 chr15:85104030 T/G cg12863693 chr15:85201151 NMB 0.41 4.63 0.38 9.27e-6 Schizophrenia; TGCT cis rs514406 0.861 rs2477741 chr1:53265278 A/G cg25767906 chr1:53392781 SCP2 0.45 5.08 0.42 1.35e-6 Monocyte count; TGCT cis rs7666738 0.791 rs13127542 chr4:98949159 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6921919 0.583 rs28360638 chr6:28362329 C/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg12667521 chr19:29218732 NA 0.55 5.9 0.47 3.29e-8 Methadone dose in opioid dependence; TGCT cis rs3806843 0.576 rs246003 chr5:140340865 C/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs546131 0.928 rs535719 chr11:34853382 A/G cg06937548 chr11:34938143 PDHX;APIP 0.62 5.64 0.45 1.1e-7 Lung disease severity in cystic fibrosis; TGCT cis rs6964587 0.839 rs6949881 chr7:91433827 C/T cg17063962 chr7:91808500 NA 0.82 8.45 0.6 6.54e-14 Breast cancer; TGCT cis rs806215 0.547 rs12540484 chr7:127370040 G/A cg11539674 chr7:127291444 SND1 -0.37 -4.66 -0.39 8.12e-6 Type 2 diabetes; TGCT cis rs7617480 0.585 rs7373072 chr3:48960017 T/A cg07636037 chr3:49044803 WDR6 0.78 6.55 0.51 1.38e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs28595532 0.920 rs17325192 chr4:119780345 A/G cg21605333 chr4:119757512 SEC24D -0.81 -5.35 -0.43 4.05e-7 Cannabis dependence symptom count; TGCT trans rs2727020 0.894 rs3862342 chr11:49357043 C/T cg03929089 chr4:120376271 NA -0.65 -6.9 -0.53 2.32e-10 Coronary artery disease; TGCT cis rs7705042 0.865 rs2043280 chr5:141513691 C/G cg07392085 chr5:141489673 NDFIP1 -0.3 -4.54 -0.38 1.3e-5 Asthma; TGCT cis rs2645424 0.635 rs6980952 chr8:11716473 C/G cg18999641 chr8:11876646 NA -0.23 -4.95 -0.41 2.32e-6 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs7017914 0.905 rs3098876 chr8:71936244 T/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs11098499 0.863 rs3775843 chr4:120427844 T/C cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.28e-9 Corneal astigmatism; TGCT cis rs710216 0.957 rs859511 chr1:43430260 C/T cg03128534 chr1:43423976 SLC2A1 0.6 4.59 0.38 1.07e-5 Red cell distribution width; TGCT cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.961 rs7619016 chr3:49272589 C/T cg05785598 chr3:49045655 WDR6 0.38 4.53 0.38 1.37e-5 Menarche (age at onset); TGCT cis rs554111 0.963 rs666371 chr1:21041555 A/G cg08890418 chr1:21044141 KIF17 0.57 5.95 0.47 2.59e-8 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs7100689 0.784 rs4934083 chr10:82116501 G/C cg01528321 chr10:82214614 TSPAN14 0.88 8.48 0.61 5.61e-14 Post bronchodilator FEV1; TGCT cis rs7666738 0.791 rs1593571 chr4:98963763 T/C cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6782228 1.000 rs11718130 chr3:128330027 G/C cg15113803 chr3:129247119 RHO 0.2 5.28 0.43 5.7e-7 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; TGCT cis rs9611565 0.512 rs715498 chr22:42148467 G/A cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs8017423 1.000 rs59052550 chr14:90665098 C/T cg04374321 chr14:90722782 PSMC1 0.78 8.11 0.59 4.18e-13 Mortality in heart failure; TGCT cis rs9527 0.545 rs7894588 chr10:104756030 A/T cg04362960 chr10:104952993 NT5C2 0.72 5.59 0.45 1.37e-7 Arsenic metabolism; TGCT cis rs7772486 0.790 rs2247429 chr6:146217769 T/C cg23711669 chr6:146136114 FBXO30 0.91 10.65 0.69 3.26e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg21644426 chr2:191273491 MFSD6 0.62 6.11 0.48 1.21e-8 Pulse pressure; TGCT cis rs113084984 0.684 rs4669745 chr2:11681572 A/G cg25804072 chr2:10829725 NOL10 0.56 4.69 0.39 7.01e-6 Breast cancer; TGCT cis rs7246657 1.000 rs8110011 chr19:37745813 G/T cg18154014 chr19:37997991 ZNF793 0.84 5.58 0.45 1.46e-7 Coronary artery calcification; TGCT cis rs7833790 0.777 rs10958042 chr8:82678393 G/T cg17211192 chr8:82754475 SNX16 -1.03 -8.39 -0.6 9.37e-14 Diastolic blood pressure; TGCT cis rs10484885 0.793 rs1465954 chr6:90475013 G/A cg13799429 chr6:90582589 CASP8AP2 0.45 4.66 0.39 7.9e-6 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2730245 1.000 rs2252502 chr7:158738634 G/C cg24397884 chr7:158709396 WDR60 -0.38 -5.08 -0.42 1.33e-6 Height; TGCT cis rs4517514 0.509 rs10830434 chr11:89912652 T/C cg05041596 chr11:89867385 NAALAD2 0.55 5.14 0.42 1.05e-6 Trans fatty acid levels; TGCT cis rs270601 0.710 rs4705852 chr5:131602807 A/G cg24060327 chr5:131705240 SLC22A5 -0.66 -6.85 -0.52 3.07e-10 Acylcarnitine levels; TGCT cis rs7727544 0.547 rs56083751 chr5:131664638 T/A cg24060327 chr5:131705240 SLC22A5 -0.53 -5.73 -0.46 7.13e-8 Blood metabolite levels; TGCT cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg27286337 chr10:134555280 INPP5A -0.41 -5.06 -0.41 1.45e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12188164 1.000 rs72717414 chr5:429818 C/G cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.76 -0.39 5.27e-6 Cystic fibrosis severity; TGCT cis rs12548874 0.618 rs10100651 chr8:95887225 G/C cg16049864 chr8:95962084 TP53INP1 -0.59 -6.7 -0.52 6.51e-10 Hemoglobin concentration; TGCT cis rs1113500 0.636 rs3853493 chr1:108637193 G/A cg22161131 chr1:109420278 GPSM2 0.49 4.54 0.38 1.34e-5 Growth-regulated protein alpha levels; TGCT trans rs10962181 0.590 rs74308120 chr9:1547609 G/A cg26433494 chr7:132068972 PLXNA4 0.48 6.82 0.52 3.48e-10 Superior frontal gyrus grey matter volume; TGCT cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg04317338 chr11:64019027 PLCB3 0.77 6.33 0.49 4e-9 Mean platelet volume; TGCT cis rs11190604 1.000 rs11190572 chr10:102232879 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg10819733 chr22:24237672 NA 0.29 4.98 0.41 2.13e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs459571 0.959 rs467379 chr9:136905474 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.69 -7.44 -0.56 1.49e-11 Platelet distribution width; TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg00786635 chr1:25594202 NA -0.52 -5.56 -0.45 1.59e-7 Erythrocyte sedimentation rate; TGCT cis rs10131894 0.611 rs174994 chr14:75434102 A/G cg08847533 chr14:75593920 NEK9 -0.64 -6.16 -0.48 9.38e-9 Coronary artery disease; TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs7752195 0.643 rs76798435 chr6:25231495 A/C cg16898833 chr6:26189333 HIST1H4D 1.27 5.88 0.47 3.55e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs7172971 0.752 rs17690068 chr15:42342929 G/A cg05886115 chr15:42349113 NA 0.31 4.88 0.4 3.21e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs6426558 0.537 rs694740 chr1:227293451 A/G cg10327440 chr1:227177885 CDC42BPA 0.57 6.57 0.51 1.26e-9 Neutrophil percentage of white cells; TGCT cis rs137603 0.502 rs137627 chr22:39716341 G/A cg17798944 chr22:39715225 SNORD43;RPL3 -0.67 -7.15 -0.54 6.74e-11 Primary biliary cholangitis; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg18538332 chr22:24372958 LOC391322 -0.87 -10.13 -0.67 6.14e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3749237 0.964 rs1799845 chr3:49847623 A/G cg07636037 chr3:49044803 WDR6 0.58 5.12 0.42 1.15e-6 Resting heart rate; TGCT cis rs651907 0.535 rs34263427 chr3:101507805 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs114540395 0.858 rs7900797 chr10:103192220 A/G cg18276125 chr10:102749041 C10orf2 0.39 4.74 0.39 5.85e-6 Schizophrenia; TGCT cis rs6500602 0.647 rs4786519 chr16:4584406 C/T cg08645402 chr16:4508243 NA 0.19 5.23 0.43 6.94e-7 Schizophrenia; TGCT cis rs1862618 0.671 rs28397234 chr5:56248428 T/G cg24531977 chr5:56204891 C5orf35 0.69 7.29 0.55 3.25e-11 Initial pursuit acceleration; TGCT cis rs4689388 0.926 rs11725494 chr4:6293855 C/T cg14416269 chr4:6271139 WFS1 0.4 5.29 0.43 5.44e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg15242686 chr22:24348715 GSTTP1 0.48 6.98 0.53 1.54e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs911555 0.617 rs7156036 chr14:103908142 A/G cg23461800 chr14:103021989 NA -0.34 -4.5 -0.37 1.57e-5 Intelligence (multi-trait analysis); TGCT cis rs8177253 0.930 rs12595 chr3:133496553 T/C cg01448562 chr3:133502909 NA -0.33 -6.67 -0.51 7.64e-10 Iron status biomarkers; TGCT cis rs79057730 0.528 rs4719313 chr7:822501 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.76 5.69 0.46 8.5e-8 Initial pursuit acceleration; TGCT cis rs9811920 0.809 rs7649349 chr3:99725629 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.18 0.42 8.58e-7 Axial length; TGCT cis rs9653442 0.576 rs6542921 chr2:100864498 C/A cg07810366 chr2:100720526 AFF3 -0.41 -6.26 -0.49 5.76e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7523050 0.643 rs12725689 chr1:109405151 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs57994353 0.861 rs13301660 chr9:139340802 C/T cg13741927 chr9:139327495 INPP5E -0.27 -6.15 -0.48 9.78e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2836950 0.545 rs4818001 chr21:40575088 T/C cg11890956 chr21:40555474 PSMG1 -0.68 -6.6 -0.51 1.09e-9 Menarche (age at onset); TGCT cis rs77861329 1.000 rs352151 chr3:52210272 C/G cg08692210 chr3:52188851 WDR51A 0.94 4.83 0.4 3.91e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs7937682 0.814 rs1784788 chr11:111486136 T/G cg09085632 chr11:111637200 PPP2R1B -1.03 -10.8 -0.7 1.39e-19 Primary sclerosing cholangitis; TGCT cis rs875971 1.000 rs697970 chr7:65560052 G/C cg11764359 chr7:65958608 NA -0.58 -4.99 -0.41 2.01e-6 Aortic root size; TGCT cis rs287982 0.611 rs115657324 chr2:9983856 A/G cg10881225 chr2:9984929 TAF1B 0.49 4.49 0.37 1.6e-5 Nonsyndromic cleft lip with cleft palate; TGCT cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg13012494 chr21:47604986 C21orf56 -0.39 -4.66 -0.39 7.88e-6 Testicular germ cell tumor; TGCT cis rs17253792 0.822 rs75560658 chr14:56079896 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7666738 0.830 rs6854703 chr4:98977586 A/T cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs453301 0.571 rs2929305 chr8:9085217 G/A cg06636001 chr8:8085503 FLJ10661 -0.56 -4.97 -0.41 2.14e-6 Joint mobility (Beighton score); TGCT cis rs4819052 1.000 rs733738 chr21:46666396 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.85 -7.2 -0.54 5.14e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6964587 1.000 rs7781066 chr7:91691946 G/T cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs10779751 0.770 rs4845853 chr1:11243470 A/G cg08854313 chr1:11322531 MTOR 0.83 8.03 0.58 6.53e-13 Body mass index; TGCT cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28595532 1.000 rs11931194 chr4:119631160 C/T cg14228332 chr4:119757509 SEC24D 1.02 5.39 0.44 3.44e-7 Cannabis dependence symptom count; TGCT cis rs6500602 0.727 rs12443748 chr16:4541831 C/T cg08645402 chr16:4508243 NA 0.18 5.06 0.41 1.44e-6 Schizophrenia; TGCT cis rs7598759 0.548 rs11686485 chr2:232360697 C/T cg19187155 chr2:232395269 NMUR1 0.48 5.62 0.45 1.2e-7 Noise-induced hearing loss; TGCT cis rs1075232 1.000 rs12437749 chr15:31649888 C/T cg01030201 chr15:31746330 NA -1.01 -5.25 -0.43 6.38e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs600231 0.706 rs4244811 chr11:65320780 G/A cg17120908 chr11:65337727 SSSCA1 0.54 5.12 0.42 1.11e-6 Bone mineral density; TGCT cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT trans rs10506458 0.834 rs12426893 chr12:63388120 G/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.54 -0.56 8.62e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs4665809 0.938 rs6742226 chr2:26342537 A/G cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs7027203 1.000 rs13288708 chr9:96509653 T/C cg13679303 chr9:96623674 NA 0.62 8.74 0.62 1.34e-14 DNA methylation (variation); TGCT cis rs10986311 0.733 rs10760356 chr9:127156083 T/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -4.94 -0.41 2.48e-6 Vitiligo; TGCT cis rs826838 0.874 rs10880943 chr12:38734317 C/T cg13010199 chr12:38710504 ALG10B 0.83 6.88 0.53 2.58e-10 Heart rate; TGCT cis rs10510102 0.872 rs12255832 chr10:123718277 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs9372498 0.536 rs55697388 chr6:118891544 C/T cg07617317 chr6:118971624 C6orf204 0.5 5.32 0.43 4.71e-7 Diastolic blood pressure; TGCT cis rs10876993 0.784 rs7314152 chr12:58017701 T/G cg15848620 chr12:58087721 OS9 0.71 5.2 0.42 7.98e-7 Celiac disease or Rheumatoid arthritis; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg26338869 chr17:61819248 STRADA 0.52 4.83 0.4 3.94e-6 Prudent dietary pattern; TGCT cis rs2239547 0.618 rs1573815 chr3:52870132 A/G cg11645453 chr3:52864694 ITIH4 -0.31 -5.42 -0.44 3.05e-7 Schizophrenia; TGCT cis rs2455799 0.533 rs2470550 chr3:15743721 C/T cg16303742 chr3:15540471 COLQ -0.26 -4.77 -0.39 5.11e-6 Mean platelet volume; TGCT cis rs9549367 0.737 rs9549712 chr13:113902355 G/A cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs6545883 0.931 rs11125885 chr2:61755728 G/C cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs11997175 0.574 rs7001404 chr8:33645219 G/A ch.8.33884649F chr8:33765107 NA 0.28 4.53 0.38 1.35e-5 Body mass index; TGCT cis rs10744422 1.000 rs3817094 chr12:123332032 T/C cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs854765 0.547 rs2955353 chr17:17948979 T/C cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs6815814 0.768 rs2013740 chr4:38891737 A/G cg02016764 chr4:38805732 TLR1 -0.28 -4.46 -0.37 1.82e-5 Breast cancer; TGCT cis rs2033711 0.728 rs4801586 chr19:58934528 A/G cg13877915 chr19:58951672 ZNF132 0.88 11.12 0.71 2.43e-20 Uric acid clearance; TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg24675658 chr1:53192096 ZYG11B -0.75 -9.11 -0.63 1.78e-15 Monocyte count; TGCT cis rs875971 0.862 rs6958294 chr7:65794796 C/A cg11764359 chr7:65958608 NA -0.55 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs60871478 0.636 rs4276575 chr7:900035 C/T cg15782153 chr7:917662 C7orf20 0.54 4.95 0.41 2.37e-6 Cerebrospinal P-tau181p levels; TGCT cis rs6424115 0.830 rs1130320 chr1:24200606 A/G cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs13256369 0.802 rs2280560 chr8:8560602 C/T cg17143192 chr8:8559678 CLDN23 0.54 4.86 0.4 3.53e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs7662218 chr4:98983126 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs68170813 0.652 rs77056542 chr7:107089751 G/C cg02696742 chr7:106810147 HBP1 -0.62 -4.63 -0.38 9.11e-6 Coronary artery disease; TGCT cis rs7178572 1.000 rs12904938 chr15:77721225 A/G cg22256960 chr15:77711686 NA -0.95 -10.73 -0.69 2.17e-19 Type 2 diabetes; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg02675527 chr2:114030824 PAX8;LOC440839 -0.5 -6.65 -0.51 8.34e-10 Lymphocyte counts; TGCT cis rs6854137 0.553 rs924511 chr4:169702964 A/G cg20607169 chr4:169750834 PALLD 0.2 4.52 0.38 1.43e-5 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9467711 0.651 rs13212534 chr6:25983010 G/A cg16898833 chr6:26189333 HIST1H4D 1.36 6.0 0.47 2.05e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs12620999 0.838 rs13007071 chr2:238038755 A/G cg23555395 chr2:238036564 NA -0.31 -5.51 -0.44 2.02e-7 Systemic lupus erythematosus; TGCT cis rs9902453 0.904 rs7225686 chr17:28356744 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg04944784 chr2:26401820 FAM59B -0.76 -6.45 -0.5 2.29e-9 Gut microbiome composition (summer); TGCT cis rs7843479 0.965 rs11135741 chr8:21801091 C/T cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs651907 0.535 rs34063583 chr3:101509948 C/T cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs9990220 0.643 rs4682103 chr3:112055793 A/G cg03525433 chr3:111259817 CD96 0.24 4.5 0.37 1.53e-5 Eosinophil percentage of white cells; TGCT cis rs597539 0.652 rs602364 chr11:68662167 C/T cg06112835 chr11:68658793 MRPL21 0.47 8.09 0.59 4.66e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7568458 0.777 rs12473819 chr2:85773061 A/G cg02493740 chr2:85810744 VAMP5 -0.31 -5.87 -0.47 3.74e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4478858 0.684 rs7528066 chr1:31749092 C/G cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs7044106 0.791 rs4836830 chr9:123483668 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.47 5.05 0.41 1.56e-6 Hip circumference adjusted for BMI; TGCT cis rs854765 0.649 rs4924821 chr17:17735952 T/C cg09796270 chr17:17721594 SREBF1 -0.25 -4.93 -0.4 2.63e-6 Total body bone mineral density; TGCT cis rs11679640 0.610 rs4350801 chr2:43113357 C/T cg00484711 chr2:42331922 NA -0.2 -4.63 -0.38 9.27e-6 White matter hyperintensity burden; TGCT cis rs875971 0.660 rs801193 chr7:66030612 A/C cg00343986 chr7:65444356 GUSB -0.24 -5.3 -0.43 5.2e-7 Aortic root size; TGCT cis rs17253792 0.822 rs10150498 chr14:56064124 G/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7714584 1.000 rs17727568 chr5:150244688 A/G cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs9674544 0.646 rs6504594 chr17:47142697 C/A cg10950924 chr17:47092072 IGF2BP1 -0.33 -4.54 -0.38 1.29e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs601339 1.000 rs7969523 chr12:123168636 T/G cg11919336 chr12:123188078 GPR109A 0.64 7.49 0.56 1.1e-11 Adiponectin levels; TGCT cis rs875971 0.619 rs12533585 chr7:65984605 G/C cg18876405 chr7:65276391 NA 0.37 5.58 0.45 1.47e-7 Aortic root size; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg15687855 chr3:44754131 ZNF502 -0.55 -6.84 -0.52 3.2e-10 Depressive symptoms; TGCT cis rs7394190 0.630 rs113799665 chr10:75575138 C/T cg07699608 chr10:75541558 CHCHD1 0.81 5.6 0.45 1.33e-7 Incident atrial fibrillation; TGCT cis rs6598955 0.724 rs12732295 chr1:26602251 C/T cg04990556 chr1:26633338 UBXN11 -0.9 -11.22 -0.71 1.34e-20 Obesity-related traits; TGCT cis rs6831352 0.918 rs6813415 chr4:100048509 T/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs78456975 0.689 rs13391992 chr2:1542153 G/A cg12573674 chr2:1569213 NA -0.49 -4.8 -0.4 4.43e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9611519 0.780 rs2235849 chr22:41653540 T/G cg06634786 chr22:41940651 POLR3H -0.52 -4.66 -0.39 7.89e-6 Neuroticism; TGCT cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg11502198 chr6:26597334 ABT1 0.55 4.89 0.4 3.05e-6 Intelligence (multi-trait analysis); TGCT cis rs2839186 0.504 rs11702278 chr21:47936295 T/G cg12379764 chr21:47803548 PCNT 0.5 5.96 0.47 2.39e-8 Testicular germ cell tumor; TGCT cis rs7267979 0.899 rs6115213 chr20:25550372 G/A cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17221829 0.699 rs7118152 chr11:89383654 T/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.64 -0.38 8.55e-6 Anxiety in major depressive disorder; TGCT cis rs3809566 1.000 rs3809566 chr15:63333724 A/G cg00520135 chr15:63333846 TPM1 -0.45 -5.56 -0.45 1.55e-7 Platelet count; TGCT cis rs453301 0.658 rs6983877 chr8:8904639 T/C cg15556689 chr8:8085844 FLJ10661 -0.67 -5.46 -0.44 2.51e-7 Joint mobility (Beighton score); TGCT trans rs17685 0.753 rs6951808 chr7:75772413 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs12220238 0.908 rs10824133 chr10:76020585 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.62 0.56 5.55e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1355223 0.583 rs2941058 chr11:34880245 C/G cg11058730 chr11:34937778 PDHX;APIP 0.79 8.32 0.6 1.36e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs67311347 0.544 rs35112505 chr3:40337075 A/G cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT trans rs7726839 0.574 rs11739866 chr5:636299 C/T cg25482853 chr8:67687455 SGK3 1.22 10.53 0.69 6.33e-19 Obesity-related traits; TGCT cis rs3008870 1.000 rs3008859 chr1:67390999 G/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs11650494 0.831 rs8065389 chr17:47456064 G/T cg08112188 chr17:47440006 ZNF652 -0.88 -4.83 -0.4 3.91e-6 Prostate cancer; TGCT cis rs9341808 0.718 rs12203867 chr6:80820833 G/T cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs72634258 0.519 rs4908487 chr1:7937437 C/T cg26816564 chr1:7831052 VAMP3 0.65 4.98 0.41 2.11e-6 Inflammatory bowel disease; TGCT cis rs950169 0.544 rs2036949 chr15:85163605 T/C cg12863693 chr15:85201151 NMB 0.44 5.25 0.43 6.32e-7 Schizophrenia; TGCT cis rs7772486 0.754 rs702318 chr6:146005873 G/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10193935 0.901 rs7605782 chr2:42502332 C/T cg27598129 chr2:42591480 NA -0.38 -5.43 -0.44 2.86e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2073300 1.000 rs12625999 chr20:23442085 A/G cg09953122 chr20:23471693 CST8 0.65 4.62 0.38 9.56e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT trans rs2688608 0.620 rs7076525 chr10:75512797 C/T cg13918328 chr10:52500089 ASAH2B 0.67 6.83 0.52 3.39e-10 Inflammatory bowel disease; TGCT cis rs514406 0.505 rs387436 chr1:53179376 C/T cg01802117 chr1:53393560 SCP2 0.4 4.75 0.39 5.55e-6 Monocyte count; TGCT cis rs9611565 0.592 rs28750375 chr22:41990644 A/C cg06634786 chr22:41940651 POLR3H -0.83 -7.66 -0.57 4.6e-12 Vitiligo; TGCT cis rs2204008 0.744 rs11495519 chr12:38060546 C/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs9325144 0.723 rs11169535 chr12:39183494 C/T cg26384229 chr12:38710491 ALG10B -0.61 -5.67 -0.45 9.5e-8 Morning vs. evening chronotype; TGCT cis rs7666738 0.830 rs13124689 chr4:98961182 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg06108461 chr20:60628389 TAF4 -0.4 -4.87 -0.4 3.35e-6 Obesity-related traits; TGCT cis rs1552244 0.882 rs13066757 chr3:10045030 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.43 -0.5 2.53e-9 Alzheimer's disease; TGCT trans rs6089829 0.962 rs1060490 chr20:61665871 A/G cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs4713118 0.955 rs9468203 chr6:27688667 A/G cg10876282 chr6:28092338 ZSCAN16 0.51 4.85 0.4 3.63e-6 Parkinson's disease; TGCT cis rs6089829 0.962 rs1116450 chr20:61658210 T/C cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7914558 1.000 rs7920251 chr10:104950197 C/T cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.67e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9379850 0.527 rs9393704 chr6:26358775 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Intelligence (multi-trait analysis); TGCT cis rs2677744 0.626 rs3743452 chr15:91497515 C/T cg23684204 chr15:91497937 RCCD1 -0.41 -6.29 -0.49 4.99e-9 Attention deficit hyperactivity disorder; TGCT cis rs7635838 0.892 rs12163566 chr3:11483096 T/A cg00170343 chr3:11313890 ATG7 0.64 6.04 0.48 1.69e-8 HDL cholesterol; TGCT cis rs7772486 0.720 rs4896844 chr6:146075224 T/C cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 0.958 rs11756510 chr6:86699794 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs6762 0.748 rs7929032 chr11:839078 G/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.47 -4.65 -0.39 8.32e-6 Mean platelet volume; TGCT cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.47 0.37 1.72e-5 Obesity-related traits; TGCT cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg24549020 chr5:56110836 MAP3K1 0.7 6.0 0.47 2.02e-8 Initial pursuit acceleration; TGCT cis rs514406 0.505 rs835609 chr1:53170494 T/C cg24675658 chr1:53192096 ZYG11B -0.75 -8.49 -0.61 5.43e-14 Monocyte count; TGCT cis rs765787 0.530 rs2433229 chr15:45515235 C/A cg24006582 chr15:45444508 DUOX1 -0.26 -5.59 -0.45 1.35e-7 Uric acid levels; TGCT cis rs1150668 0.830 rs2859365 chr6:28391465 C/T cg13525197 chr6:28411240 ZSCAN23 0.52 5.12 0.42 1.13e-6 Pubertal anthropometrics; TGCT cis rs2688608 0.592 rs7909802 chr10:75484186 G/C cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs6811802 1 rs6811802 chr4:78932838 G/C cg07207937 chr4:78783799 MRPL1 -1.17 -6.45 -0.5 2.21e-9 Left ventricular obstructive tract defect (inherited effect); TGCT cis rs3806843 0.657 rs2563283 chr5:140105978 C/A cg19875535 chr5:140030758 IK -0.36 -6.1 -0.48 1.23e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs62244186 0.627 rs3935212 chr3:44460954 G/A cg04389838 chr3:44770851 ZNF501 -0.41 -5.64 -0.45 1.12e-7 Depressive symptoms; TGCT cis rs2235642 0.750 rs763152 chr16:1658056 T/C cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.65 -0.39 8.32e-6 Coronary artery disease; TGCT cis rs1348850 0.793 rs13020788 chr2:178480714 C/A cg22681709 chr2:178499509 PDE11A -0.47 -5.66 -0.45 9.97e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4638749 0.773 rs4676190 chr2:108858619 A/G cg06795125 chr2:108905320 SULT1C2 -0.43 -5.09 -0.42 1.3e-6 Blood pressure; TGCT cis rs1008375 0.872 rs6831115 chr4:17640463 A/G cg10189774 chr4:17578691 LAP3 0.56 5.04 0.41 1.57e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs704 0.628 rs4795435 chr17:26720564 G/A cg10342447 chr17:26645325 TMEM97 -0.48 -4.87 -0.4 3.36e-6 Osteoprotegerin levels; TGCT cis rs2463822 0.925 rs1881535 chr11:62121623 C/T cg23876832 chr11:62092739 NA 0.64 4.72 0.39 6.28e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2204008 0.837 rs34381557 chr12:38181983 T/C cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg18538332 chr22:24372958 LOC391322 -1.01 -12.94 -0.76 9.13e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7584330 0.704 rs72620820 chr2:238358844 G/A cg14458575 chr2:238380390 NA 0.61 8.95 0.63 4.33e-15 Prostate cancer; TGCT cis rs1008375 1.000 rs7673500 chr4:17621383 C/T cg10189774 chr4:17578691 LAP3 0.59 5.09 0.42 1.32e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.39 0.55 1.93e-11 Schizophrenia; TGCT cis rs6426558 0.537 rs2718193 chr1:227404672 C/G cg10327440 chr1:227177885 CDC42BPA 0.53 6.19 0.49 8.13e-9 Neutrophil percentage of white cells; TGCT cis rs7178572 0.889 rs7170877 chr15:77832019 C/G cg22256960 chr15:77711686 NA -0.95 -10.78 -0.7 1.59e-19 Type 2 diabetes; TGCT cis rs7027203 0.797 rs7870672 chr9:96606693 A/C cg14598338 chr9:96623480 NA -0.61 -9.54 -0.65 1.68e-16 DNA methylation (variation); TGCT cis rs3820068 0.603 rs932602 chr1:15986087 A/G cg05660106 chr1:15850417 CASP9 0.81 7.67 0.57 4.28e-12 Systolic blood pressure; TGCT cis rs79349575 0.756 rs4793605 chr17:47035869 T/C cg26022315 chr17:47021804 SNF8 0.47 4.61 0.38 9.94e-6 Type 2 diabetes; TGCT cis rs4076764 0.846 rs4255362 chr1:163424630 G/A cg24596788 chr1:163392923 NA -0.17 -4.89 -0.4 3e-6 Motion sickness; TGCT cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT cis rs9513593 1.000 rs12875982 chr13:99850615 C/T cg21788972 chr13:99853209 UBAC2 0.62 4.98 0.41 2.05e-6 Psoriasis; TGCT cis rs9372498 0.536 rs55697388 chr6:118891544 C/T cg21191810 chr6:118973309 C6orf204 -0.39 -5.04 -0.41 1.59e-6 Diastolic blood pressure; TGCT cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg23982607 chr1:1823379 GNB1 -0.56 -8.44 -0.6 6.83e-14 Body mass index; TGCT cis rs7267979 0.966 rs6107031 chr20:25350677 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg08859206 chr1:53392774 SCP2 0.34 4.9 0.4 2.93e-6 Monocyte count; TGCT cis rs2073300 1.000 rs6036411 chr20:23441706 A/C cg09953122 chr20:23471693 CST8 -0.61 -4.5 -0.37 1.52e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg11941060 chr3:133502564 NA -0.26 -5.25 -0.43 6.38e-7 Iron status biomarkers; TGCT cis rs7000551 0.642 rs2449328 chr8:22375043 A/G cg12081754 chr8:22256438 SLC39A14 0.31 4.97 0.41 2.17e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6933660 0.760 rs3806982 chr6:151774916 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.95 -11.06 -0.7 3.42e-20 Menarche (age at onset); TGCT cis rs6988636 1.000 rs60362869 chr8:124189971 A/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9921338 0.961 rs7200667 chr16:11440404 C/A cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.37e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs2120019 0.508 rs8030528 chr15:75171825 C/T cg09165964 chr15:75287851 SCAMP5 -0.84 -6.58 -0.51 1.19e-9 Blood trace element (Zn levels); TGCT cis rs6430585 0.528 rs6743537 chr2:136702601 C/T cg07169764 chr2:136633963 MCM6 1.24 12.33 0.74 2.7e-23 Corneal structure; TGCT cis rs9372498 0.536 rs7356947 chr6:118767920 A/G cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs6087990 0.806 rs6141814 chr20:31368960 C/A cg13636640 chr20:31349939 DNMT3B 1.06 12.99 0.76 6.85e-25 Ulcerative colitis; TGCT cis rs875971 0.577 rs35072105 chr7:65609817 A/G cg18876405 chr7:65276391 NA -0.4 -6.08 -0.48 1.38e-8 Aortic root size; TGCT cis rs12753569 0.934 rs6593523 chr1:76486908 C/T cg00791851 chr1:76518896 NA -0.33 -4.44 -0.37 1.94e-5 Personality dimensions; TGCT cis rs854765 0.624 rs11657130 chr17:17733826 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.67 -0.51 7.5e-10 Total body bone mineral density; TGCT cis rs9549260 0.755 rs9549244 chr13:41218685 C/T cg21288729 chr13:41239152 FOXO1 0.98 10.15 0.67 5.43e-18 Red blood cell count; TGCT cis rs9527 0.571 rs7904113 chr10:104633114 G/T cg04362960 chr10:104952993 NT5C2 0.55 4.74 0.39 5.71e-6 Arsenic metabolism; TGCT cis rs11577318 0.853 rs12743998 chr1:26629882 G/A cg12733254 chr1:26682999 NA -0.2 -4.45 -0.37 1.89e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs3015497 0.586 rs7144714 chr14:51078585 G/A cg04730355 chr14:51134070 SAV1 -0.64 -6.14 -0.48 1.01e-8 Mean platelet volume; TGCT cis rs8032315 0.965 rs7497304 chr15:91429176 G/T cg06330618 chr15:91428456 FES 0.18 4.45 0.37 1.89e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6570726 0.577 rs9497315 chr6:145791967 C/T cg23711669 chr6:146136114 FBXO30 -0.71 -6.52 -0.51 1.62e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs939574 0.790 rs2276635 chr2:220087441 T/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.0 4.56 0.38 1.2e-5 Platelet distribution width; TGCT cis rs61990749 0.544 rs11628888 chr14:78161506 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.65 -4.59 -0.38 1.08e-5 Fibroblast growth factor basic levels; TGCT cis rs28735056 1.000 rs56376220 chr18:77609462 C/T cg20368463 chr18:77673604 PQLC1 -0.44 -5.5 -0.44 2.07e-7 Schizophrenia; TGCT cis rs17473412 0.677 rs17475188 chr5:122882751 A/G cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs10992471 0.702 rs10120915 chr9:95547725 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.27 -0.43 5.82e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3015497 0.752 rs6572682 chr14:51144800 A/T cg04730355 chr14:51134070 SAV1 -0.63 -6.03 -0.48 1.77e-8 Mean platelet volume; TGCT cis rs9467711 0.656 rs34961555 chr6:26199903 C/T cg16898833 chr6:26189333 HIST1H4D 1.44 6.24 0.49 6.22e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg13695892 chr22:41940480 POLR3H -0.85 -7.86 -0.58 1.6e-12 Vitiligo; TGCT trans rs797680 0.856 rs12124011 chr1:93652544 C/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.82 -0.52 3.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.61 -6.27 -0.49 5.54e-9 Intelligence (multi-trait analysis); TGCT cis rs9505270 0.729 rs35884426 chr6:7745935 G/A cg16988958 chr6:7987739 MGC26597 0.21 4.47 0.37 1.71e-5 Myopia (pathological); TGCT cis rs9914988 0.887 rs34644886 chr17:27168327 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs8180040 0.726 rs1463393 chr3:46994987 G/A cg27129171 chr3:47204927 SETD2 -0.71 -8.9 -0.62 5.58e-15 Colorectal cancer; TGCT cis rs5750830 0.649 rs7949 chr22:39827553 G/A cg02038168 chr22:39784481 NA -0.79 -6.79 -0.52 4.07e-10 Intelligence (multi-trait analysis); TGCT cis rs1055129 0.560 rs3682 chr17:73942150 A/G cg10935138 chr17:73851978 WBP2 0.55 4.95 0.41 2.38e-6 White matter hyperintensity burden; TGCT cis rs9611565 0.918 rs6002351 chr22:41757223 C/T cg02107564 chr22:41488750 EP300 -0.54 -4.44 -0.37 1.95e-5 Vitiligo; TGCT cis rs10489202 0.657 rs3767479 chr1:168069840 C/A cg24449463 chr1:168025552 DCAF6 -0.52 -5.45 -0.44 2.58e-7 Schizophrenia; TGCT cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg08048268 chr3:133502702 NA -0.73 -11.39 -0.71 5.35e-21 Iron status biomarkers; TGCT cis rs12762955 0.561 rs2620942 chr10:1048398 C/T cg20503657 chr10:835505 NA 0.41 5.31 0.43 4.97e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg08645402 chr16:4508243 NA 0.18 5.19 0.42 8.41e-7 Schizophrenia; TGCT cis rs79911532 0.515 rs8509 chr7:75616577 G/A cg24069840 chr7:75623858 TMEM120A 0.78 4.45 0.37 1.86e-5 Mononucleosis; TGCT cis rs4794202 0.629 rs7212099 chr17:45925890 A/G cg02219949 chr17:45927392 SP6 0.42 4.57 0.38 1.16e-5 Alzheimer's disease (cognitive decline); TGCT cis rs317689 0.690 rs7969559 chr12:69655167 A/G cg11871910 chr12:69753446 YEATS4 0.52 4.58 0.38 1.1e-5 Response to diuretic therapy; TGCT cis rs2836974 0.583 rs2735307 chr21:40713358 C/T cg17971929 chr21:40555470 PSMG1 0.61 5.52 0.44 1.87e-7 Cognitive function; TGCT cis rs4819052 0.851 rs4819040 chr21:46659762 T/C cg06618935 chr21:46677482 NA -0.34 -5.34 -0.43 4.32e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs921968 0.509 rs10932782 chr2:219353195 C/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6121246 0.529 rs6060142 chr20:30178028 A/G cg10886678 chr20:30946050 ASXL1 -0.71 -4.82 -0.4 4.04e-6 Mean corpuscular hemoglobin; TGCT cis rs6938 0.575 rs12909335 chr15:75214789 T/G cg09165964 chr15:75287851 SCAMP5 0.55 5.14 0.42 1.06e-6 Breast cancer; TGCT cis rs453301 0.686 rs11785819 chr8:8870378 T/G cg00184457 chr8:8946301 NA -0.27 -4.92 -0.4 2.72e-6 Joint mobility (Beighton score); TGCT trans rs2290610 1.000 rs2290610 chr3:3139957 C/T cg14557510 chr2:122042345 TFCP2L1 -0.69 -6.99 -0.53 1.48e-10 Blood protein levels; TGCT cis rs4975616 0.804 rs462608 chr5:1336626 T/A cg07493874 chr5:1342172 CLPTM1L -0.27 -6.55 -0.51 1.39e-9 Lung cancer; TGCT cis rs36051895 0.589 rs1322222 chr9:5190444 A/G cg02405213 chr9:5042618 JAK2 -0.72 -9.77 -0.66 4.46e-17 Pediatric autoimmune diseases; TGCT cis rs6725517 0.737 rs7576788 chr2:25083310 A/G cg01884057 chr2:25150051 NA 0.27 5.2 0.42 8.04e-7 Breast cancer; TGCT cis rs13082711 0.522 rs480238 chr3:27347577 A/T cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs10769945 0.679 rs7102920 chr11:1917872 C/T cg06503573 chr11:1949039 TNNT3 0.26 4.96 0.41 2.25e-6 DNA methylation (variation); TGCT cis rs10504229 0.906 rs2270608 chr8:58194688 T/C cg24829409 chr8:58192753 C8orf71 -0.55 -4.83 -0.4 3.91e-6 Developmental language disorder (linguistic errors); TGCT cis rs523522 0.962 rs670568 chr12:121021206 C/T cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs4727027 0.901 rs34201592 chr7:148842403 C/G cg23583168 chr7:148888333 NA -0.72 -9.17 -0.64 1.31e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7226408 0.948 rs11660669 chr18:34394481 A/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs12765878 1.000 rs9325507 chr10:105645622 C/T cg11005552 chr10:105648138 OBFC1 0.44 7.69 0.57 4.01e-12 Coronary artery disease; TGCT cis rs33794 0.901 rs28213 chr3:45290708 A/G cg18645101 chr3:44551900 NA 0.54 4.74 0.39 5.75e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs6121246 0.909 rs6060870 chr20:30303299 C/T cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs10032931 0.926 rs17024152 chr4:96456402 T/A cg03008707 chr4:96468962 UNC5C -0.34 -4.7 -0.39 6.78e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.42 6.05 0.48 1.57e-8 Lymphocyte counts; TGCT cis rs858239 0.665 rs858305 chr7:23242830 C/G cg05602783 chr7:23145260 KLHL7 0.63 5.23 0.43 6.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2549003 1.000 rs2070723 chr5:131823187 A/G cg02551604 chr5:131831745 NA -0.92 -12.33 -0.74 2.72e-23 Asthma (sex interaction); TGCT cis rs9357506 1.000 rs1345058 chr6:46306927 C/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs4819052 1.000 rs2297284 chr21:46705345 G/A cg06618935 chr21:46677482 NA -0.42 -5.37 -0.43 3.76e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13064411 0.542 rs7631335 chr3:113209166 C/T cg18753928 chr3:113234510 CCDC52 -0.54 -4.58 -0.38 1.12e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT trans rs7342694 0.965 rs9924101 chr16:81907362 T/C cg04928372 chr6:27720905 NA 0.69 6.72 0.52 5.86e-10 Coronary artery disease; TGCT cis rs35883536 0.647 rs12026951 chr1:101046273 C/T cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs4665809 1.000 rs1470097 chr2:26312840 A/G cg22920501 chr2:26401640 FAM59B -0.73 -6.28 -0.49 5.18e-9 Gut microbiome composition (summer); TGCT cis rs7010267 0.570 rs1485295 chr8:120039462 A/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs9985766 0.958 rs10011368 chr4:150988934 G/A cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs10465746 0.935 rs12758441 chr1:84352034 A/G cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg21724239 chr8:58056113 NA 0.51 5.46 0.44 2.51e-7 Developmental language disorder (linguistic errors); TGCT cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs10170846 0.789 rs972650 chr2:223520287 C/T cg25565276 chr2:223520875 FARSB 0.55 4.58 0.38 1.11e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg18876405 chr7:65276391 NA 0.37 5.85 0.46 4.19e-8 Calcium levels; TGCT cis rs4919694 0.572 rs12240508 chr10:104939232 G/A cg04362960 chr10:104952993 NT5C2 0.97 6.81 0.52 3.82e-10 Arsenic metabolism; TGCT cis rs2692947 0.526 rs4907225 chr2:96576670 C/T cg23100626 chr2:96804247 ASTL 0.38 4.61 0.38 9.79e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4886920 0.563 rs4420498 chr15:78079425 T/C cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs289997 1.000 rs289997 chr7:25569548 C/T cg14064488 chr7:26331273 SNX10 -0.34 -4.66 -0.39 8.01e-6 Breast cancer; TGCT cis rs7833790 1.000 rs7833384 chr8:82730915 T/C cg06027949 chr8:82754900 SNX16 -0.67 -4.61 -0.38 9.99e-6 Diastolic blood pressure; TGCT cis rs73001065 0.901 rs73004951 chr19:19695228 C/T cg03709012 chr19:19516395 GATAD2A 0.97 4.82 0.4 4.07e-6 LDL cholesterol; TGCT cis rs611744 0.967 rs635624 chr8:109197799 G/C cg21045802 chr8:109455806 TTC35 0.5 4.5 0.37 1.53e-5 Dupuytren's disease; TGCT cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.52 5.45 0.44 2.63e-7 Menopause (age at onset); TGCT cis rs7223966 1.000 rs8081541 chr17:61812483 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7914558 1.000 rs7081075 chr10:104929191 C/T cg04362960 chr10:104952993 NT5C2 0.61 5.45 0.44 2.6e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3099143 1.000 rs3102710 chr15:77061148 T/C cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Recalcitrant atopic dermatitis; TGCT cis rs6840360 0.868 rs6823462 chr4:152708740 G/A cg22705602 chr4:152727874 NA -0.24 -4.47 -0.37 1.75e-5 Intelligence (multi-trait analysis); TGCT cis rs854765 0.547 rs7224047 chr17:17932931 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.1 0.59 4.3e-13 Total body bone mineral density; TGCT cis rs1670533 0.769 rs6814833 chr4:1057679 A/C cg27284194 chr4:1044797 NA 0.66 5.51 0.44 1.99e-7 Recombination rate (females); TGCT trans rs17685 0.753 rs4728586 chr7:75802869 T/C cg19862616 chr7:65841803 NCRNA00174 0.53 9.03 0.63 2.83e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs514406 0.861 rs503296 chr1:53283088 A/G cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg04389838 chr3:44770851 ZNF501 -0.37 -4.83 -0.4 4.02e-6 Depressive symptoms; TGCT cis rs2816062 0.760 rs2244192 chr1:18890939 A/T cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs986417 0.818 rs10873125 chr14:61035024 G/A cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs7412746 0.658 rs3768016 chr1:150809919 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.13 0.42 1.1e-6 Melanoma; TGCT cis rs3733585 0.673 rs6814664 chr4:9956228 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4689388 0.926 rs10012946 chr4:6293350 C/T cg00701064 chr4:6280414 WFS1 -0.41 -4.85 -0.4 3.61e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs933688 0.532 rs2367292 chr5:90556785 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.55 -4.67 -0.39 7.83e-6 Smoking behavior; TGCT cis rs317689 0.684 rs315125 chr12:69758884 C/T cg20891283 chr12:69753455 YEATS4 0.56 4.71 0.39 6.52e-6 Response to diuretic therapy; TGCT cis rs8017423 0.935 rs7154695 chr14:90795705 C/G cg04374321 chr14:90722782 PSMC1 0.71 6.51 0.5 1.71e-9 Mortality in heart failure; TGCT cis rs17030434 0.906 rs57446135 chr4:154679331 A/G cg14289246 chr4:154710475 SFRP2 -0.97 -7.69 -0.57 4e-12 Electrocardiographic conduction measures; TGCT cis rs5850 0.557 rs10270788 chr7:23189000 T/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Blood protein levels; TGCT cis rs362272 0.524 rs7435601 chr4:3369645 A/G cg06533319 chr4:3265114 C4orf44 -0.27 -5.53 -0.44 1.8e-7 Serum sulfate level; TGCT cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs10746514 0.768 rs11122427 chr1:232261085 C/T cg09506761 chr1:232265262 NA -0.49 -4.99 -0.41 2.01e-6 Response to statin therapy; TGCT cis rs2204008 0.806 rs7305409 chr12:38349133 G/A cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.87e-6 Bladder cancer; TGCT cis rs11874712 1.000 rs9945751 chr18:43673265 G/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs11252926 0.528 rs11252090 chr10:436547 C/T cg13477178 chr10:375248 DIP2C 0.24 4.71 0.39 6.57e-6 Psychosis in Alzheimer's disease; TGCT cis rs4711350 0.765 rs6921772 chr6:33749686 A/G cg13859433 chr6:33739653 LEMD2 -0.32 -4.79 -0.39 4.75e-6 Schizophrenia; TGCT cis rs6504950 0.720 rs12602751 chr17:52994174 C/A cg07707039 chr17:53042137 COX11 0.27 4.66 0.39 8.15e-6 Breast cancer; TGCT cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg11279151 chr3:101281821 RG9MTD1 -0.44 -9.51 -0.65 1.94e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs1568889 0.838 rs10835304 chr11:28296529 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 10.99 0.7 4.8e-20 Bipolar disorder; TGCT cis rs6087990 0.584 rs6058897 chr20:31398105 G/T cg13636640 chr20:31349939 DNMT3B -0.85 -10.07 -0.67 8.59e-18 Ulcerative colitis; TGCT cis rs858239 0.539 rs6971673 chr7:23159523 C/G cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs11122272 0.735 rs2749716 chr1:231486908 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.61 -0.51 1.01e-9 Hemoglobin concentration; TGCT cis rs7208859 0.673 rs12103759 chr17:29235687 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs1814175 0.717 rs11040450 chr11:49650638 G/A cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs7659604 0.702 rs6826506 chr4:122710865 T/G cg06713675 chr4:122721982 EXOSC9 -0.65 -8.68 -0.61 1.88e-14 Type 2 diabetes; TGCT cis rs4906332 1.000 rs12885234 chr14:103889181 A/G cg26031613 chr14:104095156 KLC1 -0.54 -4.82 -0.4 4.04e-6 Coronary artery disease; TGCT cis rs875971 0.965 rs10267430 chr7:65743023 G/T cg11764359 chr7:65958608 NA -0.61 -5.39 -0.44 3.45e-7 Aortic root size; TGCT cis rs7246657 0.943 rs4803229 chr19:37864682 T/G cg03233940 chr19:37894644 NA -0.35 -4.54 -0.38 1.3e-5 Coronary artery calcification; TGCT cis rs67311347 0.955 rs9821036 chr3:40379007 A/G cg13683864 chr3:40499215 RPL14 -1.11 -11.84 -0.73 4.15e-22 Renal cell carcinoma; TGCT cis rs40363 0.523 rs757270 chr16:3534451 C/T cg00484396 chr16:3507460 NAT15 -0.32 -4.58 -0.38 1.11e-5 Tuberculosis; TGCT cis rs7000551 0.508 rs11780977 chr8:22245028 G/A cg12081754 chr8:22256438 SLC39A14 0.34 4.95 0.41 2.39e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9905704 0.647 rs8077332 chr17:57105223 A/G cg12560992 chr17:57184187 TRIM37 0.61 5.43 0.44 2.83e-7 Testicular germ cell tumor; TGCT cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg17054783 chr10:134559939 INPP5A 0.26 5.0 0.41 1.94e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9660180 0.846 rs10907195 chr1:1713348 C/T cg27541892 chr1:1571801 CDK11B -0.41 -5.33 -0.43 4.51e-7 Body mass index; TGCT cis rs7726839 0.561 rs4957050 chr5:579066 A/C cg09021430 chr5:549028 NA -0.37 -5.39 -0.44 3.37e-7 Obesity-related traits; TGCT cis rs896854 0.517 rs2013597 chr8:95951807 G/A cg09323728 chr8:95962352 TP53INP1 -0.43 -4.85 -0.4 3.68e-6 Type 2 diabetes; TGCT cis rs1862618 0.671 rs252897 chr5:56223000 G/A cg24531977 chr5:56204891 C5orf35 -0.73 -7.73 -0.57 3.11e-12 Initial pursuit acceleration; TGCT cis rs2486012 1.000 rs2906463 chr1:44330048 A/G cg12908607 chr1:44402522 ARTN -0.69 -5.57 -0.45 1.49e-7 Intelligence (multi-trait analysis); TGCT cis rs13064411 0.696 rs9808893 chr3:113228444 G/A cg10517650 chr3:113235015 CCDC52 -0.32 -4.45 -0.37 1.85e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs6430585 0.527 rs1446586 chr2:136407445 C/T cg07169764 chr2:136633963 MCM6 -0.94 -7.14 -0.54 7.04e-11 Corneal structure; TGCT cis rs9383153 0.793 rs2016498 chr6:16344914 C/T cg03173502 chr6:15505345 JARID2 0.77 4.8 0.4 4.54e-6 Gambling; TGCT cis rs11098499 0.954 rs1480931 chr4:120395809 G/T cg09307838 chr4:120376055 NA 0.7 6.66 0.51 8.02e-10 Corneal astigmatism; TGCT trans rs1908814 0.516 rs10113042 chr8:11793178 A/G cg15556689 chr8:8085844 FLJ10661 0.77 7.37 0.55 2.13e-11 Neuroticism; TGCT cis rs12497850 0.966 rs6792510 chr3:48723302 G/C cg06212747 chr3:49208901 KLHDC8B 0.59 5.38 0.43 3.61e-7 Parkinson's disease; TGCT cis rs3015497 0.753 rs4643225 chr14:51122205 G/C cg04730355 chr14:51134070 SAV1 -0.63 -6.19 -0.49 8.18e-9 Mean platelet volume; TGCT cis rs9308731 0.666 rs4849402 chr2:111873932 G/A cg04202892 chr2:111875749 ACOXL 0.54 6.22 0.49 7.04e-9 Chronic lymphocytic leukemia; TGCT cis rs7267979 1.000 rs2027004 chr20:25350618 C/T cg14121845 chr20:25566513 NINL -0.49 -5.38 -0.43 3.61e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6088580 0.634 rs6059887 chr20:33101102 C/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs6964587 1.000 rs415 chr7:91580490 A/G cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg06634786 chr22:41940651 POLR3H -0.86 -8.34 -0.6 1.18e-13 Vitiligo; TGCT cis rs116095464 0.558 rs1968374 chr5:249025 A/C cg22857025 chr5:266934 NA -0.34 -6.23 -0.49 6.59e-9 Breast cancer; TGCT cis rs7089973 0.604 rs11196936 chr10:116588630 C/T cg03647239 chr10:116582469 FAM160B1 0.59 5.75 0.46 6.46e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs875971 0.895 rs10755833 chr7:65913917 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg24531977 chr5:56204891 C5orf35 -0.76 -7.57 -0.56 7.52e-12 Initial pursuit acceleration; TGCT cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg19318889 chr4:1322082 MAEA 0.27 6.52 0.51 1.57e-9 Longevity; TGCT cis rs7772486 0.902 rs2144476 chr6:146322484 G/A cg05347473 chr6:146136440 FBXO30 0.51 4.92 0.4 2.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs782590 0.683 rs782633 chr2:55898203 A/G cg03859395 chr2:55845619 SMEK2 0.85 9.64 0.65 9.63e-17 Metabolic syndrome; TGCT cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs1775715 0.678 rs2778649 chr10:32146803 C/G cg14930904 chr10:32216787 ARHGAP12 0.53 5.1 0.42 1.22e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs68170813 0.559 rs2107319 chr7:106863744 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.74 -0.46 7e-8 Coronary artery disease; TGCT cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.17 -0.42 9.08e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17345786 0.906 rs11708616 chr3:101231731 C/T cg12386194 chr3:101231763 SENP7 0.63 5.94 0.47 2.63e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17539620 0.534 rs6557363 chr6:154827813 A/G cg20019720 chr6:154832845 CNKSR3 0.47 4.59 0.38 1.07e-5 Lipoprotein (a) levels; TGCT cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg12756686 chr19:29218302 NA 0.77 6.61 0.51 1.01e-9 Methadone dose in opioid dependence; TGCT cis rs7394190 0.748 rs11541237 chr10:75530962 C/T cg07699608 chr10:75541558 CHCHD1 0.8 5.21 0.42 7.72e-7 Incident atrial fibrillation; TGCT cis rs17152411 1.000 rs7089014 chr10:126590342 G/A cg07906193 chr10:126599966 NA 0.42 5.16 0.42 9.55e-7 Height; TGCT cis rs7829975 0.591 rs12677543 chr8:8644274 G/C cg06636001 chr8:8085503 FLJ10661 0.71 6.29 0.49 4.94e-9 Mood instability; TGCT cis rs7822232 0.908 rs56138570 chr8:145142206 G/A cg06495924 chr8:145149574 CYC1 -1.04 -4.49 -0.37 1.6e-5 Blood metabolite levels; TGCT cis rs617219 0.726 rs955897 chr5:78431486 A/C cg05890484 chr5:78407552 BHMT 0.38 5.13 0.42 1.1e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7208859 0.623 rs75136574 chr17:28934549 C/A cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6582630 0.576 rs3900594 chr12:38272429 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7681440 0.874 rs1372524 chr4:90776045 A/G cg26578617 chr4:90757533 SNCA -0.44 -4.54 -0.38 1.31e-5 Dementia with Lewy bodies; TGCT cis rs6060960 0.537 rs6089103 chr20:30464919 G/T cg06102403 chr20:30458708 TTLL9;DUSP15 0.41 5.11 0.42 1.19e-6 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs12510870 0.599 rs12505842 chr4:74449889 A/G cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs9611565 0.649 rs126092 chr22:42178441 A/G cg13695892 chr22:41940480 POLR3H 0.82 7.47 0.56 1.27e-11 Vitiligo; TGCT cis rs2012796 1.000 rs12436146 chr14:81821282 A/G cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs881375 0.702 rs3761847 chr9:123690239 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.42 4.88 0.4 3.16e-6 Rheumatoid arthritis; TGCT cis rs79349575 0.783 rs962272 chr17:46978283 A/G cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT trans rs7819412 0.745 rs6601569 chr8:11073578 C/T cg06636001 chr8:8085503 FLJ10661 -0.75 -7.02 -0.53 1.27e-10 Triglycerides; TGCT cis rs9916302 0.851 rs4794810 chr17:37603774 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs2562456 0.793 rs2562428 chr19:21625454 G/C cg25650185 chr19:21324782 ZNF431 0.55 4.58 0.38 1.14e-5 Pain; TGCT cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs6582630 0.519 rs12819814 chr12:38332568 G/C cg26384229 chr12:38710491 ALG10B 0.79 6.98 0.53 1.61e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs7223966 0.921 rs6504186 chr17:61863932 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9926296 0.632 rs4785716 chr16:89801127 T/C cg03388025 chr16:89894329 SPIRE2 0.32 4.69 0.39 7.03e-6 Vitiligo; TGCT cis rs6076065 0.963 rs999072 chr20:23347553 C/T cg11657817 chr20:23433608 CST11 0.28 4.55 0.38 1.25e-5 Facial morphology (factor 15, philtrum width); TGCT cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg08392591 chr16:89556376 ANKRD11 0.63 6.06 0.48 1.5e-8 Multiple myeloma (IgH translocation); TGCT cis rs67072384 1.000 rs12289259 chr11:72446731 A/C cg03713592 chr11:72463424 ARAP1 -0.94 -4.8 -0.4 4.41e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.23 -0.42 7.07e-7 Developmental language disorder (linguistic errors); TGCT cis rs4803468 0.967 rs11670583 chr19:41920440 A/T cg09537434 chr19:41945824 ATP5SL -0.9 -10.59 -0.69 4.65e-19 Height; TGCT cis rs28595532 0.702 rs72670256 chr4:119391043 G/A cg21605333 chr4:119757512 SEC24D 0.82 5.41 0.44 3.15e-7 Cannabis dependence symptom count; TGCT cis rs7824557 0.603 rs7016671 chr8:11182455 A/G cg21775007 chr8:11205619 TDH 0.66 6.45 0.5 2.27e-9 Retinal vascular caliber; TGCT cis rs36051895 0.664 rs10116560 chr9:5096433 A/G cg02405213 chr9:5042618 JAK2 -0.71 -9.43 -0.65 3.07e-16 Pediatric autoimmune diseases; TGCT cis rs11105298 0.891 rs10858890 chr12:89907166 A/G cg00757033 chr12:89920650 WDR51B 0.31 5.09 0.42 1.28e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6430585 0.528 rs309154 chr2:136726567 C/T cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs72949976 0.606 rs11898263 chr2:214030649 A/G cg08319019 chr2:214017104 IKZF2 0.84 8.21 0.59 2.46e-13 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs10484885 0.793 rs9359862 chr6:90474508 A/G cg13799429 chr6:90582589 CASP8AP2 0.45 4.66 0.39 7.9e-6 QRS interval (sulfonylurea treatment interaction); TGCT cis rs8180040 0.900 rs4858894 chr3:47484953 C/G cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs7666738 0.791 rs28579101 chr4:98843203 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.17 0.42 9.04e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg11003573 chr3:44754125 ZNF502 -0.41 -4.61 -0.38 9.8200000000000008e-06 Depressive symptoms; TGCT cis rs9611519 0.603 rs8142276 chr22:41471447 T/C cg03806693 chr22:41940476 POLR3H -0.51 -4.57 -0.38 1.14e-5 Neuroticism; TGCT cis rs950169 0.544 rs12913702 chr15:85153184 G/A cg11189052 chr15:85197271 WDR73 0.78 6.71 0.52 6.11e-10 Schizophrenia; TGCT cis rs1538970 0.924 rs10890327 chr1:45891458 C/T cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs1205863 1.000 rs1205852 chr6:11942371 A/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs8014252 0.803 rs2877672 chr14:71036259 T/C cg11204974 chr14:71022665 NA -0.55 -4.66 -0.39 7.98e-6 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs10465746 0.967 rs12140068 chr1:84394286 A/C cg10977910 chr1:84465055 TTLL7 0.65 6.29 0.49 5.05e-9 Obesity-related traits; TGCT cis rs1538970 0.962 rs9429072 chr1:45810091 C/T cg05343316 chr1:45956843 TESK2 -0.64 -5.12 -0.42 1.12e-6 Platelet count; TGCT trans rs877282 0.945 rs11253391 chr10:788752 G/A cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT trans rs1864982 0.685 rs12519616 chr5:146210844 A/G cg07017998 chr4:733617 PCGF3 0.28 7.12 0.54 7.8e-11 Alcohol dependence; TGCT cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs4843747 0.636 rs11117358 chr16:88105053 T/A cg06915872 chr16:87998081 BANP -0.3 -4.55 -0.38 1.25e-5 Menopause (age at onset); TGCT cis rs11716531 0.574 rs7624067 chr3:27267853 G/A cg02860705 chr3:27208620 NA 0.39 5.89 0.47 3.39e-8 Diastolic blood pressure; TGCT cis rs13188771 0.690 rs12521514 chr5:100898219 G/A cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs950169 0.580 rs11635597 chr15:85165699 C/T cg11189052 chr15:85197271 WDR73 0.75 6.38 0.5 3.2e-9 Schizophrenia; TGCT cis rs9399135 0.967 rs45544135 chr6:135324051 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs4654899 0.796 rs77366434 chr1:21520069 C/T cg01072550 chr1:21505969 NA -0.48 -7.14 -0.54 7.03e-11 Superior frontal gyrus grey matter volume; TGCT cis rs35883536 0.605 rs2133118 chr1:101034337 C/T cg06223162 chr1:101003688 GPR88 -0.42 -7.96 -0.58 9.26e-13 Monocyte count; TGCT cis rs6693567 0.507 rs828784 chr1:150335240 T/A cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT trans rs2727020 0.658 rs4980440 chr11:49386017 C/T cg03929089 chr4:120376271 NA -0.75 -8.58 -0.61 3.35e-14 Coronary artery disease; TGCT cis rs3784262 0.631 rs3742961 chr15:58247977 T/C cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.32 -0.49 4.39e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2718812 0.766 rs10935071 chr3:133394159 T/C cg16414030 chr3:133502952 NA -0.4 -5.2 -0.42 8.03e-7 Iron status biomarkers; TGCT trans rs2727020 0.688 rs11040338 chr11:49360601 A/G cg03929089 chr4:120376271 NA 0.73 8.73 0.62 1.45e-14 Coronary artery disease; TGCT cis rs3820928 0.934 rs1366756 chr2:227772038 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -4.82 -0.4 4.12e-6 Pulmonary function; TGCT cis rs2458413 0.903 rs2669448 chr8:105372324 T/G cg23108931 chr8:105342351 NA 0.32 5.13 0.42 1.07e-6 Paget's disease; TGCT cis rs1552244 0.816 rs56271597 chr3:10042790 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs1894292 0.527 rs2141465 chr4:74376680 G/T cg05868023 chr4:75230803 EREG 0.56 5.05 0.41 1.56e-6 Prostate cancer; TGCT cis rs7914558 0.966 rs10786724 chr10:104668942 A/G cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3813567 0.759 rs7163204 chr15:78953740 G/A cg24631222 chr15:78858424 CHRNA5 0.68 4.72 0.39 6.35e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs13242816 1.000 rs36004201 chr7:116126310 C/A cg16553024 chr7:116138462 CAV2 -0.43 -4.88 -0.4 3.26e-6 P wave duration; TGCT cis rs1797081 0.840 rs10904820 chr10:16848473 A/G cg14835575 chr10:16859367 RSU1 0.4 4.94 0.41 2.44e-6 Platelet distribution width; TGCT cis rs7614311 0.636 rs73117047 chr3:63910779 G/A cg22134162 chr3:63841271 THOC7 -0.49 -6.17 -0.48 8.78e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs425277 0.761 rs6603813 chr1:2043080 T/G cg24578937 chr1:2090814 PRKCZ 0.28 6.14 0.48 1.02e-8 Height; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs9814567 0.964 rs6776203 chr3:134234345 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs314370 0.951 rs6706 chr7:100471044 C/T cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg27535305 chr1:53392650 SCP2 -0.29 -6.13 -0.48 1.08e-8 Monocyte count; TGCT cis rs4988958 0.565 rs6760621 chr2:102999952 T/C cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma (childhood onset); TGCT cis rs6545883 0.868 rs6752938 chr2:61841588 C/T cg15711740 chr2:61764176 XPO1 -0.55 -5.19 -0.42 8.37e-7 Tuberculosis; TGCT cis rs7666738 0.830 rs35915560 chr4:98978649 C/T cg05340658 chr4:99064831 C4orf37 0.51 5.93 0.47 2.87e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs8073060 0.963 rs11080354 chr17:33872407 A/G cg19694781 chr19:47549865 TMEM160 -0.4 -7.1 -0.54 8.33e-11 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs877282 0.945 rs71491311 chr10:791747 G/A cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs3902035 0.964 rs10485390 chr6:119013074 C/G cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs9303401 0.538 rs35454383 chr17:56475599 C/T cg25039879 chr17:56429692 SUPT4H1 0.58 4.98 0.41 2.12e-6 Cognitive test performance; TGCT cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.28 -0.43 5.51e-7 Developmental language disorder (linguistic errors); TGCT cis rs10791323 0.720 rs2851117 chr11:133705905 A/G cg03690763 chr11:133734501 NA 0.31 4.78 0.39 4.96e-6 Childhood ear infection; TGCT cis rs4786125 0.665 rs1873704 chr16:6907021 C/G cg03623568 chr16:6915990 A2BP1 -0.41 -6.11 -0.48 1.21e-8 Heart rate variability traits (SDNN); TGCT cis rs10782582 0.609 rs5745485 chr1:76349534 C/G cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs13064411 0.735 rs10511326 chr3:113216325 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs6882046 0.533 rs599402 chr5:88043656 G/C cg22951263 chr5:87985283 NA -0.55 -5.88 -0.47 3.54e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs3741489 1.000 rs11147098 chr12:133406374 G/A cg08320014 chr12:133707169 ZNF10 -1.24 -4.54 -0.38 1.31e-5 Cognitive function; TGCT cis rs4389656 0.857 rs453536 chr5:6736458 T/G cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs7336332 0.598 rs45622135 chr13:28011594 T/C cg22138327 chr13:27999177 GTF3A 0.81 6.35 0.5 3.66e-9 Weight; TGCT cis rs28595532 0.920 rs116550416 chr4:119753467 A/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs317689 0.819 rs317683 chr12:69713630 T/G cg20891283 chr12:69753455 YEATS4 0.54 4.49 0.37 1.61e-5 Response to diuretic therapy; TGCT cis rs7584330 0.910 rs880930 chr2:238396872 G/C cg14458575 chr2:238380390 NA 0.5 7.15 0.54 6.63e-11 Prostate cancer; TGCT cis rs9436747 0.667 rs11208674 chr1:66039317 C/T cg14976592 chr1:65886160 LEPROT;LEPR -0.52 -4.83 -0.4 3.88e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs4455778 0.580 rs3924857 chr7:49121682 C/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs4642101 0.618 rs9877079 chr3:12821287 A/G cg05775895 chr3:12838266 CAND2 0.92 11.11 0.71 2.53e-20 QRS complex (12-leadsum); TGCT cis rs17376456 0.877 rs12153506 chr5:93360953 T/G cg25358565 chr5:93447407 FAM172A 0.92 8.4 0.6 8.88e-14 Diabetic retinopathy; TGCT cis rs7666738 0.724 rs28451676 chr4:98966990 C/T cg05340658 chr4:99064831 C4orf37 0.53 5.92 0.47 2.92e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2455799 0.559 rs2345741 chr3:15919575 A/G cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs1538970 0.924 rs7528573 chr1:45913860 T/C cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs1865760 0.713 rs1130000 chr6:25985396 A/G cg16482183 chr6:26056742 HIST1H1C 0.54 4.77 0.39 5.15e-6 Height; TGCT cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT trans rs1814175 0.754 rs28663627 chr11:50048829 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs1008375 0.933 rs7689101 chr4:17694034 G/A cg18681998 chr4:17616180 MED28 0.78 7.27 0.55 3.58e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9640161 0.789 rs3735172 chr7:150028958 C/T cg17279839 chr7:150038598 RARRES2 -0.43 -4.65 -0.39 8.28e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs910316 1.000 rs7145159 chr14:75583268 A/G cg08847533 chr14:75593920 NEK9 0.97 10.85 0.7 1.1e-19 Height; TGCT cis rs6500602 0.727 rs11644481 chr16:4581002 T/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 6.01 0.48 1.9e-8 Schizophrenia; TGCT cis rs7666738 0.830 rs13110498 chr4:98959150 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs115430947 chr4:119737149 C/A cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs8031584 0.918 rs34693097 chr15:31253984 A/G cg08704250 chr15:31115839 NA -0.35 -4.94 -0.41 2.47e-6 Huntington's disease progression; TGCT cis rs12497850 0.864 rs12493001 chr3:49181885 A/G cg16497277 chr3:49208875 KLHDC8B -0.5 -4.55 -0.38 1.25e-5 Parkinson's disease; TGCT cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.53 -6.55 -0.51 1.37e-9 Alzheimer's disease; TGCT cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7081476 0.579 rs11015436 chr10:27259820 G/A cg15286905 chr10:27530250 ACBD5 -0.62 -4.62 -0.38 9.52e-6 Age-related diseases and mortality;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs3806843 0.966 rs3806844 chr5:140206263 A/T cg19875535 chr5:140030758 IK 0.37 6.16 0.48 9.4e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2463822 0.925 rs72923272 chr11:62166832 G/A cg06239285 chr11:62104954 ASRGL1 -0.89 -5.9 -0.47 3.19e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs651907 0.514 rs11706494 chr3:101509475 A/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg17554472 chr22:41940697 POLR3H -0.43 -4.74 -0.39 5.78e-6 Vitiligo; TGCT cis rs5758343 1 rs5758343 chr22:41816652 A/T cg06850241 chr22:41845214 NA 0.28 4.45 0.37 1.92e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs10465746 0.846 rs9700285 chr1:84336685 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs6740322 0.841 rs10210507 chr2:43556636 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.58 -0.51 1.17e-9 Coronary artery disease; TGCT cis rs2862064 0.685 rs2862066 chr5:156447395 T/G cg12943317 chr5:156479607 HAVCR1 -0.39 -5.26 -0.43 6.24e-7 Platelet count; TGCT cis rs4601821 0.823 rs17115439 chr11:113264272 T/C cg14159747 chr11:113255604 NA 0.39 4.9 0.4 2.99e-6 Alcoholic chronic pancreatitis; TGCT cis rs881375 0.902 rs7021880 chr9:123673890 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 -0.44 -4.77 -0.39 4.98e-6 Rheumatoid arthritis; TGCT cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT trans rs208520 0.690 rs1100981 chr6:66852052 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs6087990 0.871 rs4911252 chr20:31330115 A/G cg13636640 chr20:31349939 DNMT3B -1.02 -14.79 -0.8 3.8e-29 Ulcerative colitis; TGCT cis rs317865 0.737 rs73234642 chr4:16186730 G/C cg04764131 chr4:16228633 TAPT1;FLJ39653 0.8 5.2 0.42 8.01e-7 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs9291683 0.588 rs2240721 chr4:10020564 G/A cg11266682 chr4:10021025 SLC2A9 0.69 10.28 0.68 2.66e-18 Bone mineral density; TGCT cis rs9584850 0.874 rs3742136 chr13:99102607 C/T cg15168958 chr13:99100528 FARP1 -0.24 -4.52 -0.38 1.4e-5 Neuroticism; TGCT cis rs6952808 1.000 rs10233560 chr7:1885415 T/C cg22963979 chr7:1858916 MAD1L1 -0.34 -5.25 -0.43 6.44e-7 Bipolar disorder and schizophrenia; TGCT cis rs9611565 0.729 rs137831 chr22:41903813 A/C cg06481639 chr22:41940642 POLR3H -0.61 -5.33 -0.43 4.41e-7 Vitiligo; TGCT cis rs9549260 0.816 rs7324090 chr13:41253958 A/T cg21288729 chr13:41239152 FOXO1 1.0 10.16 0.67 5.24e-18 Red blood cell count; TGCT cis rs10782582 0.609 rs5745553 chr1:76379135 A/T cg22875332 chr1:76189707 ACADM -0.44 -4.45 -0.37 1.89e-5 Daytime sleep phenotypes; TGCT cis rs7412746 0.611 rs9661876 chr1:150910911 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs637571 0.522 rs12797319 chr11:65735672 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.68 6.71 0.52 6.09e-10 Eosinophil percentage of white cells; TGCT cis rs7208859 0.623 rs216439 chr17:28927884 T/C cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12681287 0.752 rs9297861 chr8:87254730 G/C cg27223183 chr8:87520930 FAM82B -0.81 -5.66 -0.45 9.9e-8 Caudate activity during reward; TGCT cis rs2013441 1.000 rs12451216 chr17:20025840 C/A cg23224458 chr17:20280056 CCDC144C 0.39 4.7 0.39 6.83e-6 Obesity-related traits; TGCT cis rs7617773 0.780 rs13081169 chr3:48356797 G/A cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs986417 1.000 rs1254270 chr14:60843134 G/T cg27398547 chr14:60952738 C14orf39 -1.37 -8.31 -0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs79349575 0.783 rs12602933 chr17:47029280 G/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs9436747 0.615 rs2105462 chr1:66047880 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.03 0.41 1.69e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs6988636 1.000 rs10505430 chr8:124191933 A/G cg27053337 chr8:124217698 FAM83A -0.58 -4.81 -0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs7917772 0.503 rs11191321 chr10:104293412 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8028182 0.636 rs28610581 chr15:75812474 A/G cg20655648 chr15:75932815 IMP3 0.6 4.65 0.38 8.54e-6 Sudden cardiac arrest; TGCT cis rs6922617 0.685 rs6908026 chr6:41345896 G/A cg07798131 chr6:41471673 NA 0.97 4.79 0.4 4.65e-6 Alzheimer's disease biomarkers; TGCT cis rs17221829 0.965 rs10830362 chr11:89457908 T/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.88 -0.4 3.23e-6 Anxiety in major depressive disorder; TGCT cis rs7173743 0.525 rs7175271 chr15:79144509 A/G cg00540400 chr15:79124168 NA -0.18 -4.52 -0.38 1.4e-5 Coronary artery disease; TGCT cis rs6882076 1.000 rs6874202 chr5:156391628 T/C cg12943317 chr5:156479607 HAVCR1 -0.29 -5.6 -0.45 1.3e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs7072216 0.727 rs10748728 chr10:100171198 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs2469997 0.925 rs2447180 chr8:120355728 T/G cg00681363 chr8:120844660 TAF2 0.65 4.52 0.38 1.45e-5 Hypertension (SNP x SNP interaction); TGCT cis rs4851254 0.961 rs11680485 chr2:100749744 A/G cg23118464 chr2:100721844 AFF3 0.71 5.28 0.43 5.6e-7 Intelligence (multi-trait analysis); TGCT cis rs262150 1.000 rs262154 chr7:158773936 G/A cg19418458 chr7:158789849 NA -0.46 -4.66 -0.39 7.89e-6 Facial morphology (factor 20); TGCT cis rs12048904 0.512 rs932798 chr1:101249355 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.83 -7.11 -0.54 7.95e-11 Multiple sclerosis; TGCT cis rs3935685 0.874 rs4578613 chr15:78002360 A/T cg03457338 chr15:78040120 NA -0.23 -5.79 -0.46 5.55e-8 Intelligence (multi-trait analysis); TGCT cis rs13004237 1 rs13004237 chr2:172833139 A/G cg13550731 chr2:172543902 DYNC1I2 -0.81 -7.08 -0.54 9.26e-11 Schizophrenia; TGCT cis rs2688608 0.618 rs28553894 chr10:75489843 C/A cg23231163 chr10:75533350 FUT11 -0.29 -4.87 -0.4 3.37e-6 Inflammatory bowel disease; TGCT cis rs10465746 0.935 rs12133778 chr1:84367626 A/G cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs3740393 0.562 rs2297450 chr10:104503174 T/C cg05855489 chr10:104503620 C10orf26 0.74 6.05 0.48 1.57e-8 Microalbuminuria; TGCT cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg03452623 chr4:187889614 NA 0.37 5.71 0.46 7.99e-8 Lobe attachment (rater-scored or self-reported); TGCT trans rs1005277 0.579 rs2474584 chr10:38416389 C/T cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT trans rs9650657 0.572 rs4841465 chr8:10819854 C/T cg06636001 chr8:8085503 FLJ10661 -0.86 -8.42 -0.6 7.64e-14 Neuroticism; TGCT cis rs6988636 1.000 rs28624331 chr8:124190768 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs7208859 0.673 rs2433 chr17:29226228 T/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs62103177 0.810 rs62103187 chr18:77627633 G/C cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg09549813 chr16:4587862 C16orf5 -0.28 -4.51 -0.38 1.5e-5 Schizophrenia; TGCT cis rs67340775 0.541 rs200968 chr6:27859568 T/C cg26587870 chr6:27730563 NA -0.31 -4.48 -0.37 1.67e-5 Lung cancer in ever smokers; TGCT cis rs3902035 0.964 rs1891714 chr6:119009444 A/G cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs7584330 0.910 rs7606177 chr2:238394913 G/C cg08992911 chr2:238395768 MLPH 0.63 5.21 0.42 7.75e-7 Prostate cancer; TGCT cis rs2439831 0.850 rs8042868 chr15:43939642 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.48 0.37 1.69e-5 Lung cancer in ever smokers; TGCT cis rs2932538 0.922 rs6658555 chr1:113098534 C/T cg10983938 chr1:113465962 AFARP1;SLC16A1 0.22 4.64 0.38 8.78e-6 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs35146811 0.695 rs858509 chr7:99821470 A/G cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs10838634 1.000 rs7938960 chr11:46877082 T/C cg18332754 chr11:46939436 LRP4 0.89 4.77 0.39 5.13e-6 Schizophrenia; TGCT cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg09222892 chr1:25734099 RHCE -0.43 -6.92 -0.53 2.1e-10 Erythrocyte sedimentation rate; TGCT cis rs7703051 0.513 rs59014134 chr5:74589385 C/T cg19683494 chr5:74908142 NA 0.75 7.29 0.55 3.18e-11 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs597539 0.654 rs619727 chr11:68627535 A/G cg06028808 chr11:68637592 NA 0.52 6.73 0.52 5.54e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4665809 0.887 rs6546716 chr2:26263836 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.07 -0.48 1.45e-8 Gut microbiome composition (summer); TGCT cis rs1985732 1 rs1985732 chr6:26376161 A/G cg05738196 chr6:26577821 NA -0.57 -5.55 -0.45 1.66e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10782582 0.593 rs2147039 chr1:76143166 C/T cg10523679 chr1:76189770 ACADM -0.71 -7.4 -0.55 1.81e-11 Daytime sleep phenotypes; TGCT cis rs17001868 1.000 rs17001868 chr22:40778231 A/C cg07138101 chr22:40742427 ADSL 0.69 4.65 0.39 8.38e-6 Mammographic density (dense area); TGCT cis rs4499344 0.730 rs2545357 chr19:33104610 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs453301 0.686 rs13252797 chr8:8861430 A/G cg06636001 chr8:8085503 FLJ10661 0.66 5.23 0.43 6.87e-7 Joint mobility (Beighton score); TGCT cis rs2204008 0.806 rs3922574 chr12:38329069 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs56176327 0.600 rs7628207 chr3:49754970 T/C cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Intelligence (multi-trait analysis); TGCT cis rs2832191 0.791 rs2832198 chr21:30498240 C/T cg08807101 chr21:30365312 RNF160 0.63 5.87 0.47 3.66e-8 Dental caries; TGCT cis rs11190604 1.000 rs2495739 chr10:102335507 C/T cg23241863 chr10:102295624 HIF1AN 0.67 4.9 0.4 2.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs644799 0.965 rs2950522 chr11:95524719 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9611565 0.546 rs34077262 chr22:42061639 A/G cg06481639 chr22:41940642 POLR3H 0.61 5.3 0.43 5.06e-7 Vitiligo; TGCT cis rs1903068 0.853 rs12331471 chr4:56001509 T/C cg09978860 chr4:56023921 NA 0.57 6.47 0.5 2.1e-9 Endometriosis; TGCT cis rs4478858 0.684 rs7544946 chr1:31749736 T/C cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg15242686 chr22:24348715 GSTTP1 0.44 5.5 0.44 2.06e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT trans rs2243480 0.803 rs13224048 chr7:65993766 G/A cg07424592 chr7:64974309 NA 1.31 8.32 0.6 1.36e-13 Diabetic kidney disease; TGCT cis rs12497850 0.931 rs7616815 chr3:48779715 C/T cg05785598 chr3:49045655 WDR6 0.34 4.61 0.38 9.92e-6 Parkinson's disease; TGCT cis rs10540 1.000 rs35898083 chr11:484469 C/T cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs981844 0.683 rs1105495 chr4:154756867 T/C cg14289246 chr4:154710475 SFRP2 -0.96 -8.97 -0.63 3.91e-15 Response to statins (LDL cholesterol change); TGCT cis rs916888 0.773 rs169201 chr17:44790203 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 -0.61 -5.07 -0.41 1.42e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1857353 1.000 rs74089232 chr1:75884420 T/C cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7826238 0.623 rs2976893 chr8:8338219 G/T cg15556689 chr8:8085844 FLJ10661 -0.56 -5.12 -0.42 1.11e-6 Systolic blood pressure; TGCT cis rs6430585 0.591 rs12475553 chr2:136483355 G/T cg07169764 chr2:136633963 MCM6 1.12 10.49 0.69 8.04e-19 Corneal structure; TGCT cis rs600550 0.857 rs12221613 chr11:60002262 A/C cg18570331 chr11:60101691 MS4A6E 0.5 4.45 0.37 1.89e-5 Lipoprotein-associated phospholipase A2 activity and mass; TGCT cis rs36051895 0.632 rs12337480 chr9:5134567 T/A cg02405213 chr9:5042618 JAK2 -0.75 -10.52 -0.69 6.97e-19 Pediatric autoimmune diseases; TGCT cis rs8103278 1.000 rs17571725 chr19:46290822 C/T cg11657440 chr19:46296263 DMWD -0.58 -5.71 -0.46 7.73e-8 Coronary artery disease; TGCT cis rs7089973 0.604 rs61596353 chr10:116597763 T/C cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs4906332 0.933 rs4906330 chr14:103971202 T/G cg26031613 chr14:104095156 KLC1 -0.54 -4.66 -0.39 8.15e-6 Coronary artery disease; TGCT cis rs2120019 0.935 rs12591119 chr15:75355944 A/G cg17294928 chr15:75287854 SCAMP5 -0.84 -6.3 -0.49 4.75e-9 Blood trace element (Zn levels); TGCT cis rs78487399 0.665 rs17031016 chr2:43764442 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -5.35 -0.43 4.09e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg09737314 chr17:6899359 ALOX12 0.49 5.22 0.42 7.18e-7 Tonsillectomy; TGCT cis rs868036 0.681 rs28688285 chr15:68110297 T/C cg05925327 chr15:68127851 NA -0.48 -4.46 -0.37 1.83e-5 Restless legs syndrome; TGCT cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg25811766 chr13:21894605 NA 0.26 5.27 0.43 5.79e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9733 0.596 rs12086472 chr1:150697710 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs751728 0.664 rs12190029 chr6:33749152 T/A cg13859433 chr6:33739653 LEMD2 -0.32 -5.64 -0.45 1.1e-7 Crohn's disease; TGCT cis rs2836950 0.501 rs35994303 chr21:40686020 C/T cg22974920 chr21:40686053 BRWD1 -0.51 -4.53 -0.38 1.35e-5 Menarche (age at onset); TGCT cis rs7666738 0.830 rs921521 chr4:98838339 A/G cg17366294 chr4:99064904 C4orf37 0.72 7.56 0.56 7.78e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs4891159 0.790 rs7234653 chr18:74111988 C/T cg24786174 chr18:74118243 ZNF516 -0.62 -9.75 -0.66 5.12e-17 Longevity; TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs936229 0.768 rs11072509 chr15:75114374 C/G cg10253484 chr15:75165896 SCAMP2 -0.66 -5.34 -0.43 4.28e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2439831 1.000 rs2254321 chr15:43707542 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.22 0.49 6.97e-9 Lung cancer in ever smokers; TGCT cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.85 -6.05 -0.48 1.57e-8 Gut microbiome composition (summer); TGCT cis rs6570726 0.791 rs446362 chr6:145878716 G/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1348850 0.793 rs12990917 chr2:178487259 T/G cg22681709 chr2:178499509 PDE11A -0.47 -5.66 -0.45 9.97e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2072499 0.966 rs2842882 chr1:156165342 T/G cg06970220 chr1:156163860 SLC25A44 0.73 6.46 0.5 2.13e-9 Testicular germ cell tumor; TGCT cis rs7412746 0.658 rs4970988 chr1:150950062 A/G cg09365446 chr1:150670422 GOLPH3L -0.35 -4.93 -0.41 2.54e-6 Melanoma; TGCT cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg19774624 chr17:42201019 HDAC5 -0.84 -10.18 -0.67 4.67e-18 Total body bone mineral density; TGCT cis rs72781680 0.898 rs12623333 chr2:24111823 T/G cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs1153858 1.000 rs7163720 chr15:45639374 G/A cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs7178572 0.568 rs11853460 chr15:77515319 C/T cg15453836 chr15:77711506 NA -0.44 -4.92 -0.4 2.67e-6 Type 2 diabetes; TGCT cis rs12579753 0.879 rs12829053 chr12:82161926 T/A cg07988820 chr12:82153109 PPFIA2 -0.68 -7.51 -0.56 1.01e-11 Resting heart rate; TGCT cis rs7584330 0.780 rs9973650 chr2:238380266 G/A cg14458575 chr2:238380390 NA 0.46 7.57 0.56 7.49e-12 Prostate cancer; TGCT cis rs2730245 0.583 rs2788473 chr7:158649280 T/C cg24397884 chr7:158709396 WDR60 0.37 4.73 0.39 6.11e-6 Height; TGCT cis rs2235642 0.928 rs2076435 chr16:1607574 C/T cg10465839 chr16:1584050 IFT140;TMEM204 -0.29 -4.83 -0.4 3.88e-6 Coronary artery disease; TGCT cis rs7818688 0.697 rs11782590 chr8:95970158 G/C cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs28785552 0.897 rs7259466 chr19:53239369 G/A cg04754360 chr19:53238445 ZNF611 -0.67 -5.42 -0.44 2.95e-7 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs11098499 0.754 rs11732087 chr4:120239831 A/G cg09307838 chr4:120376055 NA 0.6 5.78 0.46 5.75e-8 Corneal astigmatism; TGCT cis rs9611565 0.879 rs4820437 chr22:41761290 T/C cg13695892 chr22:41940480 POLR3H -0.85 -8.45 -0.6 6.59e-14 Vitiligo; TGCT cis rs586688 0.625 rs481966 chr1:201655746 A/G cg07139329 chr1:201708558 NAV1 -0.52 -5.32 -0.43 4.74e-7 Obesity-related traits; TGCT cis rs2639990 1.000 rs609303 chr18:72895242 C/T cg03972071 chr18:72917163 ZADH2 0.79 5.47 0.44 2.42e-7 Vascular endothelial growth factor levels; TGCT cis rs9811920 0.598 rs793470 chr3:99548274 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.54 -6.49 -0.5 1.87e-9 Axial length; TGCT trans rs2727020 0.595 rs10466496 chr11:49501514 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.03 -0.53 1.25e-10 Coronary artery disease; TGCT cis rs2115630 0.967 rs11073731 chr15:85355113 C/A cg12501888 chr15:85177176 SCAND2 -0.51 -4.82 -0.4 4.19e-6 P wave terminal force; TGCT cis rs523522 0.962 rs2233676 chr12:120933607 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs7959452 0.590 rs11177619 chr12:69758871 G/A cg20891283 chr12:69753455 YEATS4 0.83 8.61 0.61 2.8e-14 Blood protein levels; TGCT cis rs9811920 0.838 rs12488245 chr3:99835254 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.41 -4.47 -0.37 1.73e-5 Axial length; TGCT cis rs2594989 0.733 rs9882513 chr3:11558377 T/C cg00170343 chr3:11313890 ATG7 -0.68 -5.36 -0.43 3.97e-7 Circulating chemerin levels; TGCT trans rs9992966 0.510 rs10017486 chr4:188634426 G/C cg21037265 chr19:6481819 DENND1C -0.48 -6.65 -0.51 8.5e-10 Trans fatty acid levels; TGCT cis rs9894429 1.000 rs7406003 chr17:79597597 C/T cg21028142 chr17:79581711 NPLOC4 0.29 6.86 0.52 2.94e-10 Eye color traits; TGCT cis rs6049375 1.000 rs6049370 chr20:24046836 C/T cg14741141 chr20:24973699 C20orf3 -0.76 -4.87 -0.4 3.33e-6 Erectile dysfunction and prostate cancer treatment; TGCT trans rs1814175 0.615 rs4545557 chr11:50027329 A/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs13256369 0.851 rs13266562 chr8:8564065 T/C cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs9948 0.655 rs17119562 chr2:97381844 G/C cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs2996428 0.667 rs111640545 chr1:3752792 G/A cg13057898 chr1:3703894 LRRC47 0.21 4.62 0.38 9.46e-6 Red cell distribution width; TGCT cis rs7959452 0.640 rs12370042 chr12:69692420 C/G cg14784868 chr12:69753453 YEATS4 0.68 6.95 0.53 1.81e-10 Blood protein levels; TGCT cis rs7843479 0.965 rs13278159 chr8:21799737 C/A cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs3780378 0.935 rs7875908 chr9:5081334 C/T cg02405213 chr9:5042618 JAK2 -0.62 -8.3 -0.6 1.48e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs12477438 0.520 rs2171359 chr2:99795360 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs7572733 0.534 rs1518365 chr2:198809410 T/C cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs7481584 0.624 rs1077335 chr11:3030524 A/G cg26513837 chr11:3014269 NAP1L4 -0.44 -4.51 -0.38 1.51e-5 Calcium levels; TGCT cis rs13418410 0.539 rs35866672 chr2:33842174 G/A cg04131969 chr2:33951647 MYADML -0.78 -7.55 -0.56 8.23e-12 Non-response to antidepressants and depression; TGCT cis rs1828853 1.000 rs1403275 chr11:82111758 A/C cg08066407 chr11:81789082 NA 0.67 4.8 0.4 4.55e-6 Curve progression in adolescent idiopathic scoliosis; TGCT cis rs2153535 0.580 rs9505467 chr6:8520219 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs8013055 0.898 rs8004007 chr14:105971435 G/C cg23356831 chr14:105996513 TMEM121 0.41 6.39 0.5 3.04e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7582180 0.764 rs7425449 chr2:100928393 A/G cg14675211 chr2:100938903 LONRF2 0.52 4.98 0.41 2.1e-6 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.555 rs10880520 chr12:38464111 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs12541335 0.692 rs2290274 chr8:22214374 C/T cg26039829 chr8:22132926 PIWIL2 0.28 5.2 0.42 8.03e-7 Hypertriglyceridemia; TGCT cis rs2299587 0.554 rs2073566 chr8:17743655 G/A cg04898035 chr8:17640624 MTUS1 -0.2 -4.67 -0.39 7.77e-6 Economic and political preferences; TGCT cis rs2180341 1.000 rs9401950 chr6:127655485 C/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs11031096 0.711 rs11031156 chr11:4179021 C/T cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.43e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1401999 0.966 rs1533682 chr3:183634879 A/G cg01324343 chr3:183735012 ABCC5 0.84 11.21 0.71 1.41e-20 Anterior chamber depth; TGCT cis rs2115630 1.000 rs11073730 chr15:85354596 C/T cg17173187 chr15:85201210 NMB -0.39 -4.76 -0.39 5.4e-6 P wave terminal force; TGCT cis rs16966142 1.000 rs3890534 chr16:89835289 A/G cg26513180 chr16:89883248 FANCA -0.88 -5.33 -0.43 4.57e-7 Caffeine consumption; TGCT cis rs12048904 0.930 rs11166529 chr1:101333733 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 4.56 0.38 1.21e-5 Multiple sclerosis; TGCT cis rs10510102 0.872 rs12258234 chr10:123712343 G/C cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT trans rs7248779 0.512 rs12610522 chr19:2413228 C/T cg25835954 chr13:50160062 RCBTB1 0.79 7.51 0.56 9.92e-12 Cortisol levels (saliva); TGCT trans rs797680 0.856 rs1335679 chr1:93645182 C/T cg27528825 chr2:159282178 CCDC148 -0.35 -6.85 -0.52 3.08e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7267979 0.903 rs6050482 chr20:25226327 C/T cg16686733 chr20:25566563 NINL 0.55 5.58 0.45 1.47e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17376456 0.757 rs10066431 chr5:93198204 A/G cg25358565 chr5:93447407 FAM172A 0.98 7.67 0.57 4.38e-12 Diabetic retinopathy; TGCT cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg21724239 chr8:58056113 NA 0.5 5.31 0.43 4.87e-7 Developmental language disorder (linguistic errors); TGCT cis rs6992820 0.900 rs34751862 chr8:56703319 C/G cg06880721 chr8:56792545 LYN -0.55 -4.68 -0.39 7.33e-6 Mean platelet volume; TGCT cis rs7267979 0.816 rs374701 chr20:25483616 A/G cg14121845 chr20:25566513 NINL 0.46 4.76 0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5762813 0.524 rs5762835 chr22:29230754 A/G cg02153584 chr22:29168773 CCDC117 0.78 5.31 0.43 4.91e-7 Hematocrit;Hemoglobin concentration; TGCT cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg20203395 chr5:56204925 C5orf35 -0.65 -4.56 -0.38 1.2e-5 Initial pursuit acceleration; TGCT cis rs11764590 0.950 rs11514731 chr7:2051503 C/G cg25834613 chr7:1915315 MAD1L1 -0.52 -5.06 -0.41 1.45e-6 Neuroticism; TGCT cis rs11920090 0.932 rs56819515 chr3:170712913 T/A cg07434518 chr3:170136327 CLDN11 -0.59 -4.45 -0.37 1.88e-5 Fasting blood glucose;Fasting blood glucose (BMI interaction);Homeostasis model assessment of beta-cell function; TGCT cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs992157 0.764 rs3731861 chr2:219191256 T/C cg00012203 chr2:219082015 ARPC2 -0.73 -6.61 -0.51 1.04e-9 Colorectal cancer; TGCT cis rs616402 0.564 rs602601 chr1:10567058 C/T cg17425144 chr1:10567563 PEX14 0.56 8.14 0.59 3.58e-13 Breast size; TGCT cis rs9910055 0.920 rs2855818 chr17:42290015 G/A cg19774624 chr17:42201019 HDAC5 -0.82 -7.94 -0.58 1.04e-12 Total body bone mineral density; TGCT cis rs9611519 0.894 rs13053242 chr22:41459486 G/A cg13695892 chr22:41940480 POLR3H -0.54 -4.75 -0.39 5.56e-6 Neuroticism; TGCT cis rs174601 0.861 rs174581 chr11:61606683 G/A cg20584555 chr11:61717780 BEST1 -0.23 -4.45 -0.37 1.88e-5 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs910316 0.763 rs175042 chr14:75470833 A/T cg08847533 chr14:75593920 NEK9 -0.84 -8.92 -0.63 5.19e-15 Height; TGCT cis rs17221829 0.733 rs112601489 chr11:89365849 A/C cg02982614 chr11:89391479 FOLH1B -0.28 -4.88 -0.4 3.25e-6 Anxiety in major depressive disorder; TGCT cis rs798554 0.679 rs1636249 chr7:2884283 T/G cg13628971 chr7:2884303 GNA12 0.54 4.56 0.38 1.19e-5 Height; TGCT cis rs2447097 0.935 rs2447094 chr17:2294048 A/C cg27406664 chr17:2294951 MNT 0.3 6.7 0.52 6.41e-10 Autism spectrum disorder; TGCT cis rs7246657 0.678 rs2972446 chr19:38129893 G/A cg18154014 chr19:37997991 ZNF793 -0.69 -4.67 -0.39 7.7e-6 Coronary artery calcification; TGCT cis rs10186029 0.623 rs10497996 chr2:213997865 T/C cg08319019 chr2:214017104 IKZF2 0.53 4.48 0.37 1.64e-5 Systemic sclerosis; TGCT cis rs7027203 0.964 rs7853688 chr9:96523254 C/A cg14598338 chr9:96623480 NA 0.58 8.57 0.61 3.49e-14 DNA methylation (variation); TGCT cis rs73110464 0.609 rs6580923 chr12:53358352 A/G cg14581129 chr12:53358946 NA -0.63 -6.78 -0.52 4.39e-10 Cancer (pleiotropy); TGCT cis rs4660261 0.562 rs3011223 chr1:44318286 T/C cg12908607 chr1:44402522 ARTN -0.64 -7.66 -0.57 4.69e-12 Intelligence (multi-trait analysis); TGCT cis rs670523 0.804 rs12128541 chr1:156003992 A/G cg05700447 chr1:155978627 NA -0.18 -4.49 -0.37 1.62e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs3772130 0.924 rs55643643 chr3:121440197 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.85 0.4 3.66e-6 Cognitive performance; TGCT cis rs1865760 0.622 rs9295685 chr6:26071725 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.79 7.44 0.56 1.47e-11 Height; TGCT cis rs36051895 0.664 rs10117501 chr9:5094246 G/A cg02405213 chr9:5042618 JAK2 -0.78 -10.82 -0.7 1.31e-19 Pediatric autoimmune diseases; TGCT cis rs2721195 0.967 rs748195 chr8:145682514 T/C cg13257436 chr8:145726034 PPP1R16A -0.32 -4.96 -0.41 2.27e-6 Age at first birth; TGCT cis rs1887596 0.624 rs9579026 chr13:27123830 C/T cg01312412 chr13:27282625 NA 0.26 4.59 0.38 1.09e-5 Facial morphology (factor 3, length of philtrum); TGCT cis rs10507380 0.824 rs77168898 chr13:27921242 G/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs7772486 0.790 rs9399571 chr6:146282061 A/G cg23711669 chr6:146136114 FBXO30 -0.87 -9.69 -0.66 6.98e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg25660036 chr4:7070649 GRPEL1 -0.68 -5.95 -0.47 2.6e-8 Monocyte percentage of white cells; TGCT cis rs13217239 0.646 rs10946891 chr6:26973215 T/C cg02458000 chr6:26745757 NA 0.5 4.61 0.38 9.84e-6 Schizophrenia; TGCT cis rs727479 0.502 rs3825800 chr15:51506663 A/C cg19946085 chr15:51559439 CYP19A1 -0.31 -4.52 -0.38 1.42e-5 Estradiol levels; TGCT cis rs875971 0.825 rs6951503 chr7:65718936 T/G cg11764359 chr7:65958608 NA -0.54 -4.69 -0.39 7.03e-6 Aortic root size; TGCT cis rs2153535 0.580 rs1932284 chr6:8477694 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1401999 0.714 rs1533683 chr3:183635488 C/T cg01324343 chr3:183735012 ABCC5 0.74 8.86 0.62 7.21e-15 Anterior chamber depth; TGCT cis rs9381040 1.000 rs9381040 chr6:41154650 C/T cg03526776 chr6:41159608 TREML2 0.34 6.97 0.53 1.62e-10 Alzheimer's disease (late onset); TGCT cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs6977660 0.660 rs61670426 chr7:19790460 A/G cg07541023 chr7:19748670 TWISTNB 0.85 4.84 0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs916888 0.773 rs199451 chr17:44801784 G/A cg01570182 chr17:44337453 NA 1.08 9.71 0.66 6.43e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6831352 0.918 rs2602893 chr4:100044095 G/T cg12011299 chr4:100065546 ADH4 0.43 5.02 0.41 1.71e-6 Alcohol dependence; TGCT trans rs1005277 0.579 rs2474584 chr10:38416389 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs992157 1.000 rs3731859 chr2:219124222 G/A cg00012203 chr2:219082015 ARPC2 0.77 8.2 0.59 2.56e-13 Colorectal cancer; TGCT cis rs7666738 0.830 rs1967980 chr4:98966426 C/G cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 0.698 rs4372193 chr1:46853233 G/T cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs9388451 0.626 rs3799712 chr6:126075103 A/G cg05901451 chr6:126070800 HEY2 -1.04 -12.94 -0.76 8.99e-25 Brugada syndrome; TGCT cis rs3806843 0.547 rs246033 chr5:140332115 A/C cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1008375 0.932 rs9291660 chr4:17663414 A/G cg18681998 chr4:17616180 MED28 0.95 10.23 0.68 3.5e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4819052 0.819 rs8134084 chr21:46693295 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6545883 0.868 rs2518933 chr2:61797030 C/A cg15711740 chr2:61764176 XPO1 -0.59 -5.71 -0.46 7.8e-8 Tuberculosis; TGCT cis rs28595532 0.841 rs115907265 chr4:119730593 G/A cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs231513 0.954 rs231498 chr17:41975251 C/G cg26893861 chr17:41843967 DUSP3 -0.69 -5.16 -0.42 9.31e-7 Cognitive function; TGCT cis rs3796352 1.000 rs58660500 chr3:53086573 C/T cg27565382 chr3:53032988 SFMBT1 0.43 4.6 0.38 1.01e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2243480 0.666 rs1880311 chr7:65276752 G/C cg07424592 chr7:64974309 NA -1.4 -7.6 -0.56 6.46e-12 Diabetic kidney disease; TGCT cis rs10992471 0.598 rs10761156 chr9:95171852 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.63 6.12 0.48 1.13e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2688608 0.592 rs10762559 chr10:75486453 G/C cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.78e-6 Inflammatory bowel disease; TGCT cis rs11249608 0.548 rs13156530 chr5:178475017 C/T cg01312482 chr5:178451176 ZNF879 -0.5 -4.93 -0.41 2.55e-6 Pubertal anthropometrics; TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs7027203 0.717 rs7869328 chr9:96588782 A/G cg13679303 chr9:96623674 NA -0.67 -10.55 -0.69 5.94e-19 DNA methylation (variation); TGCT cis rs4845570 0.749 rs11586446 chr1:151712488 A/G cg07092448 chr1:151763213 TDRKH -1.02 -7.36 -0.55 2.17e-11 Coronary artery disease; TGCT cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs7119 0.700 rs2867311 chr15:77902191 A/C cg27398640 chr15:77910606 LINGO1 0.32 6.7 0.52 6.54e-10 Type 2 diabetes; TGCT cis rs7568458 0.709 rs11895399 chr2:85753806 C/A cg17127132 chr2:85788382 GGCX 0.51 4.73 0.39 5.89e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10746514 0.786 rs9308486 chr1:232246418 A/G cg09506761 chr1:232265262 NA 0.44 4.54 0.38 1.32e-5 Response to statin therapy; TGCT cis rs61935443 0.720 rs10859780 chr12:95282601 T/C cg21533806 chr12:95267307 NA 0.52 4.49 0.37 1.61e-5 Schizophrenia; TGCT cis rs7267979 1.000 rs448396 chr20:25440269 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1552244 0.572 rs68013239 chr3:10165711 G/T cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg27454412 chr7:1067447 C7orf50 0.57 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs11722228 0.549 rs73212830 chr4:10078759 A/T cg26043149 chr18:55253948 FECH 1.15 11.28 0.71 9.49e-21 Gout;Urate levels;Serum uric acid levels; TGCT trans rs7618501 1.000 rs7618501 chr3:49772647 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs11710292 chr3:53117798 T/C cg15956490 chr3:53032818 SFMBT1 0.5 5.38 0.43 3.65e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs950027 0.620 rs1719246 chr15:45625479 T/A cg14582100 chr15:45693742 SPATA5L1 0.48 6.07 0.48 1.44e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs4788439 0.901 rs8045116 chr16:24994761 G/A cg07626409 chr16:25250191 ZKSCAN2 0.32 4.45 0.37 1.87e-5 Blood metabolite levels; TGCT cis rs12643440 0.538 rs60281935 chr4:17143251 G/A cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs6076065 0.707 rs2424555 chr20:23417705 A/G cg11657817 chr20:23433608 CST11 0.3 5.14 0.42 1.04e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs7715806 0.500 rs17649362 chr5:75008958 C/T cg19683494 chr5:74908142 NA 0.56 4.85 0.4 3.63e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs11627546 0.615 rs61980615 chr14:70366377 T/C cg10496350 chr14:71275911 MAP3K9 -0.94 -4.44 -0.37 1.96e-5 Red blood cell traits; TGCT cis rs4563143 0.663 rs10417671 chr19:29235335 T/C cg04546413 chr19:29218101 NA 0.76 6.73 0.52 5.48e-10 Methadone dose in opioid dependence; TGCT cis rs7267979 1.000 rs2258617 chr20:25274318 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2445762 0.642 rs8041933 chr15:51617746 G/A cg00184732 chr15:51633821 GLDN 0.52 5.35 0.43 4.11e-7 Hormone measurements; TGCT cis rs28595532 0.920 rs114724233 chr4:119754918 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs151997 0.962 rs27271 chr5:50183369 A/G cg06027927 chr5:50259733 NA 0.47 4.83 0.4 4e-6 Callous-unemotional behaviour; TGCT cis rs7044106 0.718 rs1960421 chr9:123394894 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.63 6.78 0.52 4.27e-10 Hip circumference adjusted for BMI; TGCT cis rs11105298 0.891 rs6538189 chr12:89885923 C/A cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs72945132 0.678 rs7113595 chr11:70236819 T/C cg00319359 chr11:70116639 PPFIA1 1.0 7.12 0.54 7.76e-11 Coronary artery disease; TGCT cis rs6430585 0.697 rs6724569 chr2:136516970 G/A cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2404602 0.647 rs1443115 chr15:77041829 T/C cg22467129 chr15:76604101 ETFA 0.47 4.58 0.38 1.13e-5 Blood metabolite levels; TGCT cis rs644799 0.710 rs11021311 chr11:95505227 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.29 0.6 1.54e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6740322 0.895 rs9309097 chr2:43554397 T/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.58 -0.51 1.17e-9 Coronary artery disease; TGCT cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.82 8.75 0.62 1.29e-14 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.529 rs6060195 chr20:30185638 C/T cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs7635838 0.718 rs2249051 chr3:11403234 G/A cg00170343 chr3:11313890 ATG7 0.66 6.47 0.5 2.01e-9 HDL cholesterol; TGCT cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs7572733 0.555 rs7590828 chr2:198940251 A/G cg00792783 chr2:198669748 PLCL1 -0.53 -4.82 -0.4 4.19e-6 Dermatomyositis; TGCT cis rs6912958 0.967 rs6905947 chr6:88161949 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.64 -6.31 -0.49 4.58e-9 Monocyte percentage of white cells; TGCT cis rs12971120 0.685 rs34780792 chr18:72173278 G/A cg26446133 chr18:72167187 CNDP2 -0.36 -5.96 -0.47 2.48e-8 Refractive error; TGCT cis rs1691799 0.867 rs1168341 chr12:66759080 G/C cg16791601 chr12:66731901 HELB -0.29 -6.18 -0.49 8.39e-9 White blood cell count (basophil); TGCT cis rs3849570 0.500 rs9868037 chr3:81517244 A/T cg07356753 chr3:81810745 GBE1 0.59 4.88 0.4 3.26e-6 Waist circumference;Body mass index; TGCT cis rs60154123 0.505 rs115881613 chr1:210040369 C/T cg12034118 chr1:209979487 IRF6 0.65 4.56 0.38 1.2e-5 Coronary artery disease; TGCT cis rs4499344 0.526 rs10412141 chr19:33034189 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.68 -5.73 -0.46 7.27e-8 Mean platelet volume; TGCT cis rs2806561 0.664 rs4620508 chr1:23307438 C/T cg12483005 chr1:23474871 LUZP1 0.39 4.99 0.41 2.03e-6 Height; TGCT cis rs7264396 0.561 rs6142470 chr20:34570579 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.83 -0.4 4.01e-6 Total cholesterol levels; TGCT cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT trans rs62103177 0.810 rs62103191 chr18:77628769 C/G cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs7552404 1.000 rs4949876 chr1:76173377 C/T cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs13108904 0.539 rs13141992 chr4:1340765 C/T cg03303774 chr4:1407052 NA 0.38 5.9 0.47 3.24e-8 Obesity-related traits; TGCT cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg03407747 chr17:6899364 ALOX12 0.54 5.85 0.47 4.06e-8 Tonsillectomy; TGCT cis rs910187 0.678 rs6018328 chr20:45813180 T/C cg27589058 chr20:45804311 EYA2 -0.36 -7.88 -0.58 1.44e-12 Migraine; TGCT cis rs7412746 0.634 rs12096831 chr1:150864113 T/G cg04414720 chr1:150670196 GOLPH3L 0.39 4.64 0.38 8.63e-6 Melanoma; TGCT cis rs2046867 0.908 rs9841994 chr3:72820503 A/C cg25664220 chr3:72788482 NA -0.53 -6.67 -0.51 7.68e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg06753367 chr22:24256600 NA 0.23 4.47 0.37 1.73e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10791323 0.559 rs10750549 chr11:133730820 A/G cg15485101 chr11:133734466 NA 0.42 5.26 0.43 6.25e-7 Childhood ear infection; TGCT cis rs8084125 0.832 rs62105175 chr18:74948498 T/C cg15443732 chr18:74961078 GALR1 0.48 4.7 0.39 6.75e-6 Obesity-related traits; TGCT cis rs9457247 0.967 rs1794696 chr6:167396174 T/C cg23791538 chr6:167370224 RNASET2 -0.53 -5.19 -0.42 8.38e-7 Crohn's disease; TGCT cis rs2214681 0.521 rs2527049 chr7:147742084 A/G cg23013736 chr7:148584684 NA -0.23 -4.59 -0.38 1.08e-5 Bone mineral density; TGCT cis rs1005277 0.579 rs2474608 chr10:38457109 C/T cg13531842 chr10:38383804 ZNF37A -0.39 -4.64 -0.38 8.78e-6 Extrinsic epigenetic age acceleration; TGCT cis rs7927592 0.513 rs556442 chr11:68192690 G/A cg16797656 chr11:68205561 LRP5 -0.29 -5.11 -0.42 1.17e-6 Total body bone mineral density; TGCT trans rs1005277 0.505 rs10827835 chr10:38150709 G/A cg17830980 chr10:43048298 ZNF37B 0.73 8.42 0.6 7.98e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2798269 0.604 rs2185883 chr13:22157265 A/G cg18095732 chr13:22033692 ZDHHC20 -0.5 -4.45 -0.37 1.88e-5 PR segment; TGCT cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg20891558 chr2:74357851 NA 0.65 9.59 0.65 1.25e-16 Gestational age at birth (maternal effect); TGCT cis rs910316 1.000 rs11623413 chr14:75588824 C/T cg11812906 chr14:75593930 NEK9 -0.72 -7.17 -0.54 5.83e-11 Height; TGCT cis rs929354 1.000 rs1182385 chr7:157040583 C/T cg05182265 chr7:156933206 UBE3C 0.27 5.91 0.47 3.02e-8 Body mass index; TGCT cis rs208515 0.525 rs10944870 chr6:66687757 G/C cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs1215050 0.547 rs11097572 chr4:98627088 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9859260 0.744 rs492288 chr3:195784210 C/T cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT trans rs11671005 0.504 rs3794964 chr19:59070916 T/C cg22037779 chr5:139682734 PFDN1 -0.85 -6.91 -0.53 2.25e-10 Mean platelet volume; TGCT cis rs6121246 0.529 rs6060142 chr20:30178028 A/G cg18721089 chr20:30220636 NA -0.57 -6.21 -0.49 7.33e-9 Mean corpuscular hemoglobin; TGCT cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg11890956 chr21:40555474 PSMG1 1.13 12.1 0.74 1e-22 Cognitive function; TGCT cis rs6570726 0.905 rs421032 chr6:145827771 A/G cg23711669 chr6:146136114 FBXO30 0.7 6.46 0.5 2.12e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs17712049 1.000 rs62447153 chr7:48200023 G/A cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs7542091 0.635 rs985431 chr1:210043948 A/T cg22029157 chr1:209979665 IRF6 0.64 6.1 0.48 1.23e-8 Monobrow; TGCT cis rs6089584 0.888 rs6061973 chr20:60610870 C/T cg16423285 chr20:60520624 NA -0.61 -6.46 -0.5 2.12e-9 Body mass index; TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg19536664 chr17:6899085 ALOX12 0.39 6.1 0.48 1.23e-8 Tonsillectomy; TGCT trans rs1814175 0.935 rs11040462 chr11:49683158 G/A cg03929089 chr4:120376271 NA -0.63 -7.14 -0.54 6.84e-11 Height; TGCT trans rs1005277 0.579 rs2474569 chr10:38383491 C/G cg17830980 chr10:43048298 ZNF37B -0.85 -10.98 -0.7 5.08e-20 Extrinsic epigenetic age acceleration; TGCT cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs909674 0.865 rs5757683 chr22:39850174 G/A cg11247378 chr22:39784982 NA -0.72 -8.68 -0.61 1.9e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7647973 0.626 rs62260723 chr3:49872124 T/C cg05785598 chr3:49045655 WDR6 -0.42 -5.23 -0.42 7.1e-7 Menarche (age at onset); TGCT cis rs9911578 0.935 rs7216698 chr17:57007495 G/A cg05425664 chr17:57184151 TRIM37 -0.56 -5.42 -0.44 2.99e-7 Intelligence (multi-trait analysis); TGCT cis rs1865760 1.000 rs9358893 chr6:25921761 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.21 0.49 7.42e-9 Height; TGCT cis rs2013441 1.000 rs17686798 chr17:20029170 A/C cg23224458 chr17:20280056 CCDC144C -0.36 -4.47 -0.37 1.72e-5 Obesity-related traits; TGCT cis rs1023500 0.505 rs134901 chr22:42683520 C/T cg15557168 chr22:42548783 NA -0.2 -4.68 -0.39 7.46e-6 Schizophrenia; TGCT cis rs10851411 0.862 rs1060291 chr15:42820589 G/A cg23803468 chr15:43513504 EPB42 0.29 5.33 0.43 4.57e-7 Glucose homeostasis traits; TGCT cis rs6598955 1.000 rs6598955 chr1:26619649 C/T cg04990556 chr1:26633338 UBXN11 0.86 10.39 0.68 1.4e-18 Obesity-related traits; TGCT cis rs6570726 0.935 rs421268 chr6:145845558 A/T cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs77861329 1.000 rs28452586 chr3:52176007 A/G cg08692210 chr3:52188851 WDR51A 0.81 4.57 0.38 1.17e-5 Macrophage inflammatory protein 1b levels; TGCT cis rs2243480 1.000 rs958550 chr7:65635679 C/T cg18252515 chr7:66147081 NA 1.13 7.12 0.54 7.8e-11 Diabetic kidney disease; TGCT cis rs17401966 0.838 rs34636442 chr1:10427459 T/G cg19773385 chr1:10388646 KIF1B -0.23 -5.38 -0.44 3.57e-7 Hepatocellular carcinoma; TGCT cis rs2795502 0.873 rs3123753 chr10:43404899 C/T cg20628663 chr10:43360327 NA 0.36 5.45 0.44 2.66e-7 Blood protein levels; TGCT cis rs2228479 0.618 rs72477006 chr16:89950299 G/C cg06558623 chr16:89946397 TCF25 0.56 6.8 0.52 3.92e-10 Skin colour saturation; TGCT cis rs6490294 0.904 rs4767264 chr12:112425746 C/T cg10833066 chr12:111807467 FAM109A -0.36 -5.9 -0.47 3.25e-8 Mean platelet volume; TGCT cis rs76419734 0.850 rs17036341 chr4:106796829 C/G cg24545054 chr4:106630052 GSTCD;INTS12 0.95 4.74 0.39 5.71e-6 Post bronchodilator FEV1; TGCT cis rs3087591 0.887 rs2905796 chr17:29537586 G/A cg24425628 chr17:29625626 OMG;NF1 0.48 6.99 0.53 1.52e-10 Hip circumference; TGCT trans rs7618501 0.602 rs2624816 chr3:50117312 T/G cg21659725 chr3:3221576 CRBN -0.73 -8.46 -0.6 6.37e-14 Intelligence (multi-trait analysis); TGCT cis rs9814567 0.964 rs9820150 chr3:134223011 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6095298 0.595 rs1078624 chr20:47434385 A/G cg12307787 chr20:48099359 KCNB1 0.41 4.44 0.37 1.95e-5 Intelligence (multi-trait analysis); TGCT cis rs1997103 0.954 rs1917769 chr7:55392325 T/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1865760 0.566 rs4529296 chr6:26083135 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs554111 0.656 rs3121071 chr1:21128420 C/T cg01072550 chr1:21505969 NA 0.34 5.12 0.42 1.15e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs523522 0.962 rs687873 chr12:121019634 G/A cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs10875746 0.904 rs11168422 chr12:48519505 T/G cg20731937 chr12:48336164 NA 0.61 4.82 0.4 4.14e-6 Longevity (90 years and older); TGCT cis rs67311347 1.000 rs7636719 chr3:40432084 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.29e-6 Renal cell carcinoma; TGCT cis rs7208859 0.623 rs11658022 chr17:29085359 A/T cg14008862 chr17:28927542 LRRC37B2 0.77 4.61 0.38 9.76e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7267979 1.000 rs8125868 chr20:25324410 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9902453 1.000 rs4533340 chr17:28277951 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 7.0 0.53 1.44e-10 Coffee consumption (cups per day); TGCT cis rs10986311 0.862 rs10818950 chr9:127130137 A/G cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.95 -0.41 2.33e-6 Vitiligo; TGCT cis rs6424115 0.800 rs6665733 chr1:24200158 T/C cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs1532993 0.518 rs34218077 chr4:98602104 C/G cg05340658 chr4:99064831 C4orf37 -0.42 -5.02 -0.41 1.72e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs8078723 0.714 rs3785550 chr17:38149727 C/T cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs17253792 0.822 rs78395034 chr14:56069783 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3087591 1.000 rs9904169 chr17:29572518 C/T cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.51 -0.56 1.01e-11 Hip circumference; TGCT cis rs11627546 0.615 rs6573916 chr14:70366603 C/G cg10496350 chr14:71275911 MAP3K9 -0.89 -4.5 -0.37 1.52e-5 Red blood cell traits; TGCT cis rs17331151 0.573 rs28552648 chr3:52865593 G/A cg27565382 chr3:53032988 SFMBT1 0.47 5.96 0.47 2.42e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6952808 0.771 rs10244946 chr7:1921068 A/G cg22963979 chr7:1858916 MAD1L1 0.38 6.01 0.48 1.91e-8 Bipolar disorder and schizophrenia; TGCT cis rs28595532 0.920 rs10018977 chr4:119785229 C/T cg21605333 chr4:119757512 SEC24D 1.44 8.24 0.6 2.03e-13 Cannabis dependence symptom count; TGCT cis rs6840360 0.642 rs7657747 chr4:152394254 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg21016266 chr12:122356598 WDR66 0.4 5.05 0.41 1.54e-6 Mean corpuscular volume; TGCT cis rs4711350 0.765 rs756139 chr6:33755541 G/A cg18005901 chr6:33739558 LEMD2 -0.59 -6.61 -0.51 1.01e-9 Schizophrenia; TGCT cis rs9868809 0.772 rs2286651 chr3:48694147 G/A cg00383909 chr3:49044727 WDR6 1.13 6.17 0.48 8.69e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs4824093 0.610 rs60036544 chr22:50264019 C/T cg20569369 chr22:51173646 NA 0.28 4.69 0.39 7.23e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs8062405 1.000 rs4788095 chr16:28831359 T/C cg09754948 chr16:28834200 ATXN2L 0.61 4.54 0.38 1.34e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs587847 0.558 rs638182 chr15:37658915 C/T cg16890051 chr15:37175029 LOC145845 -0.39 -4.6 -0.38 1.03e-5 Intraocular pressure; TGCT cis rs12142240 0.659 rs72677591 chr1:46818219 T/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs8016982 0.634 rs1035948 chr14:81682392 C/T cg01989461 chr14:81687754 GTF2A1 0.81 8.55 0.61 3.82e-14 Schizophrenia; TGCT cis rs17253792 0.571 rs112129578 chr14:56028415 T/C cg24579896 chr14:56047964 C14orf33;KTN1 0.69 4.46 0.37 1.81e-5 Putamen volume; TGCT cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg17554472 chr22:41940697 POLR3H -0.49 -5.24 -0.43 6.58e-7 Vitiligo; TGCT cis rs7246657 0.722 rs6508736 chr19:38061757 A/G cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs56399783 0.803 rs7811164 chr7:2822416 G/A cg19731401 chr7:2775893 GNA12 0.34 4.8 0.4 4.43e-6 Childhood ear infection; TGCT cis rs3911569 0.511 rs530356 chr11:95069694 A/G cg00455452 chr11:94474125 NA -0.67 -4.47 -0.37 1.72e-5 Alzheimer disease and age of onset; TGCT cis rs7698623 0.850 rs1381958 chr4:88796785 T/C cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg24531977 chr5:56204891 C5orf35 0.97 8.9 0.62 5.58e-15 Initial pursuit acceleration; TGCT cis rs6693567 0.565 rs12093148 chr1:150265173 G/A cg09579323 chr1:150459698 TARS2 -0.52 -4.76 -0.39 5.38e-6 Migraine; TGCT cis rs6750795 0.746 rs1667301 chr2:232423717 C/T cg19187155 chr2:232395269 NMUR1 0.52 5.96 0.47 2.46e-8 Height; TGCT cis rs2832191 0.740 rs2832168 chr21:30463695 G/A cg24692254 chr21:30365293 RNF160 1.0 11.65 0.72 1.19e-21 Dental caries; TGCT cis rs9467711 1.000 rs6939978 chr6:26328462 G/C cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1008375 0.646 rs13145480 chr4:17565143 T/C cg16339924 chr4:17578868 LAP3 -0.75 -6.29 -0.49 5.06e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2239547 0.563 rs2581820 chr3:53020544 A/G cg10802521 chr3:52805072 NEK4 0.59 5.53 0.44 1.85e-7 Schizophrenia; TGCT cis rs903263 0.901 rs4907194 chr1:84665968 G/C cg09664975 chr1:84543551 PRKACB 0.49 4.65 0.39 8.48e-6 Breast cancer (male); TGCT cis rs6893300 0.524 rs10516146 chr5:179166974 A/G cg14593053 chr5:179126677 CANX 0.5 5.75 0.46 6.63e-8 Resting heart rate; TGCT cis rs3772130 0.540 rs7627354 chr3:121562434 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.59 5.43 0.44 2.8e-7 Cognitive performance; TGCT cis rs708547 0.836 rs1625691 chr4:57845740 T/C cg25525207 chr4:57843836 C4orf14;POLR2B -0.54 -5.15 -0.42 9.88e-7 Response to bleomycin (chromatid breaks); TGCT cis rs4786125 0.587 rs1473515 chr16:6923092 T/G cg03623568 chr16:6915990 A2BP1 -0.44 -6.44 -0.5 2.39e-9 Heart rate variability traits (SDNN); TGCT cis rs12188164 1.000 rs34847072 chr5:437862 G/C cg21144161 chr5:423903 AHRR 0.26 5.04 0.41 1.59e-6 Cystic fibrosis severity; TGCT cis rs8010715 1.000 rs8010715 chr14:24609147 T/C cg23112188 chr14:24563095 PCK2 -0.41 -4.92 -0.4 2.69e-6 IgG glycosylation; TGCT cis rs10197940 0.662 rs4335940 chr2:152275304 A/G cg19508488 chr2:152266495 RIF1 -0.74 -6.66 -0.51 7.77e-10 Lung cancer; TGCT cis rs7824557 0.564 rs7828263 chr8:11231886 A/G cg21775007 chr8:11205619 TDH -0.59 -5.47 -0.44 2.35e-7 Retinal vascular caliber; TGCT cis rs6089584 0.854 rs6061985 chr20:60622362 T/C cg13665807 chr20:60559372 TAF4 -0.46 -4.9 -0.4 2.87e-6 Body mass index; TGCT cis rs3796352 1.000 rs11706035 chr3:53011868 A/T cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT trans rs7819412 0.659 rs4073948 chr8:10772644 A/T cg15556689 chr8:8085844 FLJ10661 -0.75 -7.0 -0.53 1.4e-10 Triglycerides; TGCT cis rs2836974 0.644 rs9978775 chr21:40694526 A/G cg11644478 chr21:40555479 PSMG1 -0.54 -4.69 -0.39 7.19e-6 Cognitive function; TGCT cis rs35883536 0.566 rs10783141 chr1:101043897 G/A cg14855972 chr1:101004472 GPR88 -0.23 -4.44 -0.37 1.97e-5 Monocyte count; TGCT cis rs11148252 0.553 rs7999849 chr13:53249414 A/G cg00495681 chr13:53174319 NA 0.64 6.46 0.5 2.14e-9 Lewy body disease; TGCT cis rs66573146 0.656 rs66517061 chr4:6935163 C/G cg05069807 chr4:6945702 TBC1D14 0.35 4.92 0.4 2.74e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs72945132 0.882 rs7928686 chr11:70134528 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs854765 0.618 rs9908017 chr17:17774422 C/T cg04398451 chr17:18023971 MYO15A 0.28 4.51 0.38 1.49e-5 Total body bone mineral density; TGCT cis rs763121 0.853 rs5757187 chr22:39021522 A/G cg06022373 chr22:39101656 GTPBP1 -0.78 -7.44 -0.56 1.48e-11 Menopause (age at onset); TGCT cis rs2688608 0.618 rs28718766 chr10:75489844 C/A cg15838173 chr10:75533400 FUT11 -0.31 -5.16 -0.42 9.66e-7 Inflammatory bowel disease; TGCT cis rs7772486 0.875 rs2777476 chr6:146345024 A/G cg13319975 chr6:146136371 FBXO30 -0.52 -4.65 -0.39 8.22e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3749237 0.595 rs1464568 chr3:49458266 G/A cg07636037 chr3:49044803 WDR6 0.62 5.83 0.46 4.59e-8 Resting heart rate; TGCT cis rs9611565 0.694 rs4822032 chr22:41925535 T/C cg13695892 chr22:41940480 POLR3H -0.83 -8.63 -0.61 2.52e-14 Vitiligo; TGCT cis rs7923609 0.935 rs10995477 chr10:65010672 T/C cg08743896 chr10:65200160 JMJD1C -0.34 -4.55 -0.38 1.25e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs16866061 1.000 rs72974222 chr2:225424143 C/T cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs708547 0.836 rs781554 chr4:57717537 C/T cg25525207 chr4:57843836 C4orf14;POLR2B 0.53 4.45 0.37 1.89e-5 Response to bleomycin (chromatid breaks); TGCT cis rs7000551 0.779 rs2443507 chr8:22373231 G/A cg12081754 chr8:22256438 SLC39A14 0.3 4.87 0.4 3.26e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs28595532 0.920 rs116145969 chr4:119770908 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs6121246 0.567 rs6120937 chr20:30219721 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs6840360 0.571 rs17275577 chr4:152519899 G/A cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg10295955 chr4:187884368 NA -1.02 -15.84 -0.82 1.42e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs6545883 0.525 rs1729662 chr2:61391305 G/A cg15711740 chr2:61764176 XPO1 -0.51 -4.54 -0.38 1.29e-5 Tuberculosis; TGCT cis rs1018836 0.608 rs10094978 chr8:91509054 C/T cg16814680 chr8:91681699 NA -0.67 -6.8 -0.52 3.85e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6570726 0.516 rs9376932 chr6:145729490 T/C cg23711669 chr6:146136114 FBXO30 0.61 5.53 0.44 1.82e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2241685 0.764 rs12471967 chr2:1941173 G/A cg21862353 chr2:1801628 MYT1L -0.54 -5.11 -0.42 1.2e-6 Attention deficit hyperactivity disorder; TGCT cis rs265548 0.608 rs265544 chr19:17903479 G/C cg04517722 chr19:17905589 B3GNT3 0.46 5.88 0.47 3.63e-8 Tumor biomarkers; TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg03188948 chr7:1209495 NA 0.47 6.42 0.5 2.6e-9 Longevity;Endometriosis; TGCT cis rs739496 0.843 rs598711 chr12:111973140 A/G cg10833066 chr12:111807467 FAM109A 0.35 4.58 0.38 1.13e-5 Platelet count; TGCT cis rs4953076 0.613 rs11124981 chr2:44462133 A/T cg04920474 chr2:44395004 PPM1B 0.59 5.87 0.47 3.66e-8 Height; TGCT cis rs6582630 0.502 rs1915395 chr12:38420726 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.94 0.41 2.52e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs41271951 0.512 rs16832976 chr1:151038135 T/C cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs568617 1.000 rs694994 chr11:65653309 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.57 5.17 0.42 9.24e-7 Crohn's disease; TGCT cis rs8177179 0.967 rs4994581 chr3:133437563 T/C cg16262614 chr3:133464971 TF 0.34 4.52 0.38 1.44e-5 Iron status biomarkers (transferrin levels); TGCT cis rs2932538 0.922 rs999923 chr1:113110548 T/C cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs861020 0.630 rs628445 chr1:210004953 C/T cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs7772486 0.594 rs6901864 chr6:146023050 C/A cg13319975 chr6:146136371 FBXO30 0.53 4.7 0.39 6.72e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9473924 0.618 rs61236902 chr6:50813055 C/G cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs9549367 0.789 rs3794422 chr13:113893729 G/A cg00898013 chr13:113819073 PROZ -0.4 -4.94 -0.41 2.52e-6 Platelet distribution width; TGCT cis rs78487399 0.808 rs13396401 chr2:43701213 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.69 4.55 0.38 1.27e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9640161 0.663 rs1916932 chr7:150021644 T/C cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 9.08e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs9467773 0.869 rs742090 chr6:26415637 A/C cg09904177 chr6:26538194 HMGN4 -0.53 -4.9 -0.4 2.91e-6 Intelligence (multi-trait analysis); TGCT cis rs11077998 0.840 rs9910991 chr17:80481193 G/A cg10255544 chr17:80519551 FOXK2 0.23 4.45 0.37 1.92e-5 Reticulocyte fraction of red cells; TGCT cis rs9399135 0.967 rs4896122 chr6:135295081 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg23172400 chr8:95962367 TP53INP1 -0.36 -6.07 -0.48 1.44e-8 Type 2 diabetes; TGCT cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg24829409 chr8:58192753 C8orf71 -0.64 -5.27 -0.43 5.83e-7 Developmental language disorder (linguistic errors); TGCT cis rs10276381 1.000 rs10276381 chr7:28190121 A/G cg23620719 chr7:28220237 JAZF1 -0.85 -5.46 -0.44 2.54e-7 Crohn's disease; TGCT cis rs7582180 0.663 rs2053263 chr2:100971407 A/G cg08017756 chr2:100939284 LONRF2 -0.31 -5.01 -0.41 1.85e-6 Intelligence (multi-trait analysis); TGCT cis rs3125734 0.633 rs1864836 chr10:64028538 C/G cg19640130 chr10:64028056 RTKN2 -0.4 -5.17 -0.42 9.02e-7 Rheumatoid arthritis; TGCT cis rs10804591 1.000 rs2811434 chr3:129339615 G/T cg07730360 chr3:128845626 NA -0.2 -4.66 -0.39 7.91e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2072499 0.750 rs2241109 chr1:156173082 C/T cg24450063 chr1:156163899 SLC25A44 1.13 10.64 0.69 3.48e-19 Testicular germ cell tumor; TGCT cis rs7726839 0.540 rs72703095 chr5:601789 T/C cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs2677744 1.000 rs1550636 chr15:91477461 A/G cg22288577 chr15:91498497 RCCD1 0.49 5.01 0.41 1.82e-6 Attention deficit hyperactivity disorder; TGCT cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg05985448 chr10:134359359 INPP5A 0.23 4.99 0.41 2.01e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7267979 0.866 rs437635 chr20:25456888 A/G cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.644 rs4926928 chr1:53210163 G/T cg22166914 chr1:53195759 ZYG11B 0.5 9.65 0.65 8.98e-17 Monocyte count; TGCT cis rs10883723 0.847 rs3808934 chr10:104264280 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7666738 0.830 rs11932942 chr4:98998939 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg06238570 chr21:40685208 BRWD1 -0.8 -8.77 -0.62 1.14e-14 Cognitive function; TGCT cis rs35883536 0.647 rs10493929 chr1:101043928 A/C cg06223162 chr1:101003688 GPR88 -0.43 -8.11 -0.59 4.18e-13 Monocyte count; TGCT cis rs4805272 0.512 rs11879141 chr19:29320335 G/A cg04546413 chr19:29218101 NA 0.72 4.97 0.41 2.16e-6 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs826838 1.000 rs7315028 chr12:38710523 G/A cg26384229 chr12:38710491 ALG10B 1.11 11.22 0.71 1.39e-20 Heart rate; TGCT cis rs4478858 0.611 rs7527645 chr1:31763787 T/C cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs921968 0.643 rs2556384 chr2:219532903 C/T cg02176678 chr2:219576539 TTLL4 -0.38 -5.47 -0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs854765 0.693 rs9907287 chr17:17774118 C/T cg04398451 chr17:18023971 MYO15A 0.29 4.57 0.38 1.15e-5 Total body bone mineral density; TGCT cis rs6121246 0.609 rs6089054 chr20:30323141 A/G cg10886678 chr20:30946050 ASXL1 -0.52 -4.44 -0.37 1.97e-5 Mean corpuscular hemoglobin; TGCT cis rs2073300 1.000 rs6132622 chr20:23442240 A/T cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs769267 0.929 rs2905424 chr19:19473445 T/C cg08509172 chr19:19383838 TM6SF2 0.34 4.46 0.37 1.78e-5 Tonsillectomy; TGCT cis rs10256972 0.685 rs10263665 chr7:1110628 A/G cg03188948 chr7:1209495 NA 0.43 5.17 0.42 9.26e-7 Longevity;Endometriosis; TGCT cis rs941408 1.000 rs1640273 chr19:2803227 C/T cg06609049 chr19:2785107 THOP1 0.83 8.2 0.59 2.61e-13 Total cholesterol levels; TGCT cis rs921968 0.541 rs496674 chr2:219432569 G/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs3020736 0.500 rs8138678 chr22:42516229 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs651907 0.535 rs13094753 chr3:101525082 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.86 0.4 3.51e-6 Colorectal cancer; TGCT cis rs2730260 0.537 rs55864635 chr7:158859744 C/T cg09066883 chr7:157932951 PTPRN2 0.44 4.83 0.4 3.96e-6 Myopia (pathological); TGCT cis rs3820068 0.705 rs72645803 chr1:15868232 G/A cg05660106 chr1:15850417 CASP9 1.15 13.74 0.78 1.14e-26 Systolic blood pressure; TGCT cis rs7923609 1.000 rs7923609 chr10:65133822 A/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.58 -0.38 1.13e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs13223928 0.666 rs9986825 chr7:3151177 C/T cg19214707 chr7:3157722 NA 0.44 5.9 0.47 3.28e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs7524258 0.867 rs35399313 chr1:7277293 T/C cg04342483 chr1:7259290 CAMTA1 -0.31 -4.52 -0.38 1.45e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7937612 0.965 rs7131046 chr11:120238534 G/A cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.62 -0.38 9.51e-6 Intraocular pressure; TGCT cis rs9902453 0.817 rs62068625 chr17:28176581 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT trans rs1814175 0.765 rs1721990 chr11:49912154 G/C cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.66e-13 Height; TGCT cis rs288326 0.561 rs80099669 chr2:183776981 G/T cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs11190604 1.000 rs7905961 chr10:102297391 G/C cg16342193 chr10:102329863 NA -0.41 -5.12 -0.42 1.15e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs5769765 0.773 rs9616382 chr22:50312979 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg08280861 chr8:58055591 NA 0.39 4.76 0.39 5.35e-6 Developmental language disorder (linguistic errors); TGCT cis rs10992471 0.603 rs10116813 chr9:95090360 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.48 -0.44 2.23e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs763014 1.000 rs8054842 chr16:672799 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.21 -0.59 2.44e-13 Height; TGCT cis rs10791097 0.667 rs4937585 chr11:130741940 A/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg08859206 chr1:53392774 SCP2 0.45 6.89 0.53 2.54e-10 Monocyte count; TGCT cis rs5769707 0.904 rs7288869 chr22:50015327 C/T cg05373962 chr22:49881684 NA -0.31 -6.29 -0.49 4.89e-9 Monocyte count;Monocyte percentage of white cells; TGCT trans rs7618501 1.000 rs4855862 chr3:49748833 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.665 rs11495668 chr12:38221018 C/T cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs11676348 0.791 rs4133195 chr2:218951245 A/G cg00012203 chr2:219082015 ARPC2 0.51 4.7 0.39 6.78e-6 Ulcerative colitis; TGCT cis rs933688 1.000 rs6867219 chr5:90718008 T/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.17 0.59 3.05e-13 Smoking behavior; TGCT cis rs2153535 0.546 rs9378559 chr6:8539058 A/T cg07606381 chr6:8435919 SLC35B3 0.54 4.99 0.41 2.02e-6 Motion sickness; TGCT cis rs9393692 0.905 rs2393592 chr6:26285560 A/G cg05868516 chr6:26286170 HIST1H4H 0.63 5.91 0.47 3.02e-8 Educational attainment; TGCT cis rs3820928 0.692 rs17416354 chr2:227770844 A/G cg11843606 chr2:227700838 RHBDD1 -0.53 -5.15 -0.42 9.84e-7 Pulmonary function; TGCT cis rs259282 0.605 rs8101920 chr19:33109270 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.52 4.79 0.4 4.59e-6 Schizophrenia; TGCT cis rs6964587 1.000 rs56072181 chr7:91690457 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs514406 0.505 rs431427 chr1:53179094 C/A cg01802117 chr1:53393560 SCP2 -0.4 -4.75 -0.39 5.55e-6 Monocyte count; TGCT cis rs12497850 0.797 rs61583136 chr3:49189195 C/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.55 0.45 1.66e-7 Parkinson's disease; TGCT cis rs317689 0.613 rs315112 chr12:69785926 T/A cg20891283 chr12:69753455 YEATS4 0.64 5.66 0.45 9.8e-8 Response to diuretic therapy; TGCT cis rs6121246 0.909 rs1994251 chr20:30287328 T/G cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs2346177 0.580 rs7565770 chr2:46683683 A/C cg26688816 chr2:46740690 ATP6V1E2 -0.42 -4.74 -0.39 5.8e-6 HDL cholesterol; TGCT cis rs6088590 0.523 rs6059913 chr20:33143288 G/A cg06115741 chr20:33292138 TP53INP2 0.54 4.72 0.39 6.29e-6 Coronary artery disease; TGCT cis rs11190604 1.000 rs11190595 chr10:102291761 T/C cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs6762477 0.748 rs11714799 chr3:50217899 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.78 -8.07 -0.59 5.08e-13 Menarche (age at onset); TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 6.05e-6 Prudent dietary pattern; TGCT cis rs6450176 1.000 rs67430852 chr5:53290586 T/A ch.5.1024479R chr5:53302184 ARL15 -0.5 -4.66 -0.39 7.96e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs6598955 0.671 rs12141563 chr1:26589636 A/G cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs7940866 0.801 rs10894288 chr11:130808679 T/C cg05962950 chr11:130786565 SNX19 0.67 6.75 0.52 5.05e-10 Schizophrenia; TGCT cis rs36051895 0.626 rs7870694 chr9:5100628 T/C cg02405213 chr9:5042618 JAK2 -0.78 -11.04 -0.7 3.71e-20 Pediatric autoimmune diseases; TGCT cis rs1943345 0.519 rs11233504 chr11:82886525 A/G cg07047830 chr11:82868014 PCF11 0.54 5.42 0.44 2.95e-7 Obesity-related traits; TGCT cis rs6570726 0.934 rs9484995 chr6:145781114 T/A cg23711669 chr6:146136114 FBXO30 -0.7 -6.53 -0.51 1.54e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs34779708 0.897 rs4934527 chr10:35281118 T/A cg04310649 chr10:35416472 CREM -0.5 -4.45 -0.37 1.91e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs1483890 0.642 rs9825845 chr3:69404572 C/A cg22125112 chr3:69402811 FRMD4B 0.28 4.57 0.38 1.18e-5 Resting heart rate; TGCT cis rs8177253 1.000 rs6439439 chr3:133481498 G/T cg20276088 chr3:133502917 NA -0.24 -4.96 -0.41 2.28e-6 Iron status biomarkers; TGCT cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs2180341 1.000 rs3798852 chr6:127636733 A/G cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs9467711 1.000 rs9467707 chr6:26327905 G/C cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6754311 0.544 rs11678022 chr2:136809033 A/T cg07169764 chr2:136633963 MCM6 -0.57 -5.6 -0.45 1.33e-7 Mosquito bite size; TGCT cis rs6582630 0.502 rs4385963 chr12:38295264 G/A cg13010199 chr12:38710504 ALG10B 0.57 4.45 0.37 1.89e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs62244186 0.606 rs6798590 chr3:44556861 T/A cg15687855 chr3:44754131 ZNF502 -0.46 -5.29 -0.43 5.45e-7 Depressive symptoms; TGCT cis rs561655 0.663 rs7938634 chr11:85845473 A/G cg07180834 chr11:85838833 NA -0.32 -4.6 -0.38 1.01e-5 Alzheimer's disease (late onset); TGCT cis rs9910055 0.530 rs11656758 chr17:42301541 A/G cg13607699 chr17:42295918 UBTF 0.96 11.05 0.7 3.49e-20 Total body bone mineral density; TGCT cis rs10851411 0.789 rs11638208 chr15:42777190 C/G cg23803468 chr15:43513504 EPB42 -0.24 -4.77 -0.39 4.98e-6 Glucose homeostasis traits; TGCT cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg07424592 chr7:64974309 NA -1.27 -7.28 -0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs6591182 0.503 rs11227241 chr11:65389890 G/C cg17480646 chr11:65405466 SIPA1 -0.55 -7.09 -0.54 9.03e-11 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs992157 0.560 rs1514132 chr2:219084082 C/T cg00012203 chr2:219082015 ARPC2 -0.81 -9.29 -0.64 6.53e-16 Colorectal cancer; TGCT cis rs2032447 0.839 rs6901039 chr6:26000885 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.88 7.55 0.56 8.16e-12 Intelligence (multi-trait analysis); TGCT cis rs3784262 0.904 rs3784263 chr15:58253062 C/T cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.59 -0.56 6.66e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs901683 0.702 rs74940001 chr10:46144294 G/A cg09623279 chr10:45395734 NA -0.49 -5.33 -0.43 4.55e-7 Red blood cell traits;Mean corpuscular volume; TGCT cis rs67072384 1.000 rs2365442 chr11:72450218 G/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs9640161 0.830 rs35840727 chr7:150063204 A/G cg10018233 chr7:150070692 REPIN1 0.31 4.63 0.38 9.16e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs1519814 0.654 rs6469882 chr8:121010471 A/G cg22335954 chr8:121166405 COL14A1 -0.36 -4.52 -0.38 1.44e-5 Breast cancer; TGCT cis rs7246657 0.943 rs8109038 chr19:38015709 A/G cg18154014 chr19:37997991 ZNF793 -0.93 -6.54 -0.51 1.48e-9 Coronary artery calcification; TGCT cis rs3008870 1.000 rs3008848 chr1:67379284 C/T cg03991309 chr1:68237761 GNG12 0.27 4.68 0.39 7.28e-6 Lymphocyte percentage of white cells; TGCT cis rs12541335 0.639 rs7834182 chr8:22163112 G/A cg07298985 chr8:22133076 PIWIL2 0.33 5.28 0.43 5.7e-7 Hypertriglyceridemia; TGCT cis rs6088580 0.634 rs4911152 chr20:32955024 T/C cg08999081 chr20:33150536 PIGU -0.27 -5.33 -0.43 4.46e-7 Glomerular filtration rate (creatinine); TGCT cis rs1887596 0.554 rs565885 chr13:27115431 C/G cg01312412 chr13:27282625 NA -0.28 -4.94 -0.41 2.46e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs7666738 0.830 rs28618180 chr4:98912184 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.2 0.54 5.03e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10751667 0.643 rs10902257 chr11:973577 T/C cg06064525 chr11:970664 AP2A2 -0.34 -7.97 -0.58 9.04e-13 Alzheimer's disease (late onset); TGCT cis rs10504229 0.636 rs115738451 chr8:58055133 A/T cg08280861 chr8:58055591 NA 0.51 5.73 0.46 7.17e-8 Developmental language disorder (linguistic errors); TGCT cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs80282103 0.618 rs11250264 chr10:1151723 A/C cg08668510 chr10:1095578 IDI1 1.05 5.31 0.43 4.8e-7 Glomerular filtration rate (creatinine); TGCT cis rs2204008 0.640 rs11520199 chr12:38211026 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT trans rs1814175 0.869 rs10769600 chr11:49681832 C/T cg03929089 chr4:120376271 NA -0.63 -7.04 -0.53 1.14e-10 Height; TGCT cis rs7729723 0.591 rs11750582 chr5:137816983 T/C cg19169342 chr5:137827400 NA 0.35 4.99 0.41 1.97e-6 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs4841097 0.806 rs6992247 chr8:8948469 G/T cg06636001 chr8:8085503 FLJ10661 0.66 4.82 0.4 4.05e-6 Platelet distribution width; TGCT cis rs8180040 0.726 rs34344887 chr3:47042161 A/G cg27129171 chr3:47204927 SETD2 0.76 9.79 0.66 4.14e-17 Colorectal cancer; TGCT cis rs2274273 0.712 rs9806049 chr14:55525589 C/A cg01923255 chr14:55878535 KIAA0831 0.58 4.85 0.4 3.6e-6 Protein biomarker; TGCT cis rs514406 0.505 rs374662 chr1:53164549 C/A cg08859206 chr1:53392774 SCP2 -0.34 -4.74 -0.39 5.65e-6 Monocyte count; TGCT trans rs7618501 0.603 rs72942333 chr3:49986118 T/C cg21659725 chr3:3221576 CRBN 0.77 9.39 0.64 3.86e-16 Intelligence (multi-trait analysis); TGCT cis rs10037670 0.530 rs58067943 chr5:153819496 T/C cg21964928 chr5:153872958 NA 0.25 4.49 0.37 1.63e-5 Behavioural disinhibition (generation interaction); TGCT cis rs2228479 0.850 rs17226512 chr16:89839976 T/C cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs1577917 0.958 rs12203457 chr6:86689277 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs2836950 0.527 rs2836958 chr21:40623526 T/C cg17971929 chr21:40555470 PSMG1 -0.54 -4.92 -0.4 2.71e-6 Menarche (age at onset); TGCT cis rs801193 0.935 rs3800820 chr7:66147178 C/T cg18876405 chr7:65276391 NA -0.33 -5.05 -0.41 1.55e-6 Aortic root size; TGCT cis rs6589563 0.609 rs12292921 chr11:116621963 T/G cg20660624 chr11:117307972 DSCAML1 -0.36 -4.63 -0.38 9.26e-6 Eosinophil counts; TGCT cis rs7809950 0.862 rs12112877 chr7:106941324 T/C cg23024343 chr7:107201750 COG5 -0.3 -4.52 -0.38 1.42e-5 Coronary artery disease; TGCT cis rs9467711 1.000 rs9467704 chr6:26319486 A/G cg16898833 chr6:26189333 HIST1H4D -1.04 -5.41 -0.44 3.12e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.81 -0.4 4.29e-6 Bipolar disorder; TGCT cis rs5750830 0.649 rs7949 chr22:39827553 G/A cg24399712 chr22:39784796 NA -1.05 -12.52 -0.75 9.61e-24 Intelligence (multi-trait analysis); TGCT cis rs9394841 0.667 rs3747749 chr6:41770604 G/A cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs9300255 0.550 rs10772997 chr12:123719880 C/A cg00376283 chr12:123451042 ABCB9 0.79 6.75 0.52 5.15e-10 Neutrophil percentage of white cells; TGCT cis rs727505 1.000 rs720613 chr7:124452670 C/T cg23710748 chr7:124431027 NA -0.27 -4.54 -0.38 1.33e-5 Lewy body disease; TGCT cis rs950776 0.678 rs12910237 chr15:78956338 C/T cg21242079 chr15:79101063 ADAMTS7 -0.31 -4.81 -0.4 4.29e-6 Sudden cardiac arrest; TGCT cis rs10493773 0.502 rs12066742 chr1:86081149 A/G cg17807903 chr1:86174739 ZNHIT6 -0.4 -4.92 -0.4 2.7e-6 Urate levels in overweight individuals; TGCT cis rs10193935 0.901 rs55978605 chr2:42573402 C/A cg27598129 chr2:42591480 NA -0.4 -5.57 -0.45 1.51e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.820 rs12503082 chr4:120284317 A/G cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg18867708 chr6:26865862 GUSBL1 -0.38 -5.03 -0.41 1.65e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg19318889 chr4:1322082 MAEA -0.24 -5.93 -0.47 2.77e-8 Longevity; TGCT cis rs2842992 0.709 rs1853257 chr6:160212710 C/G cg11366901 chr6:160182831 ACAT2 1.07 7.2 0.54 5.07e-11 Age-related macular degeneration (geographic atrophy); TGCT cis rs12142240 0.659 rs17361873 chr1:46832686 A/G cg00530320 chr1:46809349 NSUN4 0.29 6.03 0.48 1.71e-8 Menopause (age at onset); TGCT cis rs1451375 0.698 rs56233242 chr7:50634053 C/A cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs72615157 0.645 rs11771660 chr7:99851269 T/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.63 -5.16 -0.42 9.65e-7 Lung function (FEV1/FVC); TGCT cis rs7267979 0.966 rs2482948 chr20:25296499 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs713587 0.624 rs1550110 chr2:25124563 T/C cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index in non-asthmatics; TGCT cis rs8177253 1.000 rs8177247 chr3:133479499 T/G cg08439880 chr3:133502540 NA -0.31 -5.87 -0.47 3.69e-8 Iron status biomarkers; TGCT cis rs1005224 0.819 rs10147492 chr14:76155309 T/G cg25116370 chr14:76127843 TTLL5;C14orf1 -0.54 -4.72 -0.39 6.23e-6 Large artery stroke; TGCT cis rs896854 0.530 rs10956934 chr8:95992473 C/A cg16049864 chr8:95962084 TP53INP1 -0.67 -8.1 -0.59 4.32e-13 Type 2 diabetes; TGCT cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.9 7.25 0.55 3.93e-11 Platelet count; TGCT cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg02018176 chr4:1364513 KIAA1530 0.27 4.52 0.38 1.41e-5 Longevity; TGCT cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.54 -5.0 -0.41 1.91e-6 Colorectal cancer; TGCT cis rs4654899 0.802 rs17449966 chr1:21203996 A/G cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs3806843 0.608 rs246042 chr5:140330967 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs514406 0.584 rs7548832 chr1:53193576 A/T cg25767906 chr1:53392781 SCP2 -0.47 -5.2 -0.42 8.1e-7 Monocyte count; TGCT cis rs6714710 0.603 rs13034929 chr2:98402772 G/C cg26665480 chr2:98280029 ACTR1B 0.7 6.54 0.51 1.43e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT trans rs28735056 0.967 rs623546 chr18:77595228 C/T cg05926928 chr17:57297772 GDPD1 -0.71 -7.64 -0.57 5.03e-12 Schizophrenia; TGCT cis rs7617773 0.780 rs11714176 chr3:48360862 C/T cg11946769 chr3:48343235 NME6 0.82 7.08 0.54 9.69e-11 Coronary artery disease; TGCT cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg10047753 chr17:41438598 NA 0.95 9.5 0.65 2.09e-16 Menopause (age at onset); TGCT cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg02187348 chr16:89574699 SPG7 -0.62 -6.79 -0.52 4.17e-10 Multiple myeloma (IgH translocation); TGCT cis rs10744422 0.686 rs4038070 chr12:123299525 C/T cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT trans rs7819412 0.805 rs4333549 chr8:10979561 C/G cg06636001 chr8:8085503 FLJ10661 -0.75 -7.1 -0.54 8.52e-11 Triglycerides; TGCT cis rs7647973 0.922 rs7620024 chr3:49451691 G/A cg05785598 chr3:49045655 WDR6 -0.38 -4.52 -0.38 1.4e-5 Menarche (age at onset); TGCT cis rs1933488 0.931 rs7740777 chr6:153413309 G/T cg24028809 chr6:153414101 RGS17 -0.2 -4.49 -0.37 1.63e-5 Prostate cancer; TGCT cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg11301795 chr4:187892539 NA -0.33 -4.88 -0.4 3.19e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7843479 1.000 rs1032094 chr8:21820479 A/T cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs3858526 0.883 rs7481882 chr11:5944221 A/G cg13902645 chr11:5959945 NA -0.45 -4.65 -0.39 8.37e-6 DNA methylation (variation); TGCT trans rs28595532 0.557 rs12498329 chr4:119311524 C/T cg26518628 chr1:97050305 NA -0.52 -7.12 -0.54 7.52e-11 Cannabis dependence symptom count; TGCT cis rs778371 0.676 rs17164 chr2:233593499 C/T cg08000102 chr2:233561755 GIGYF2 0.69 7.65 0.57 4.94e-12 Schizophrenia; TGCT cis rs3820928 0.874 rs7576081 chr2:227843634 C/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.59 -0.38 1.05e-5 Pulmonary function; TGCT cis rs7845219 0.544 rs7017487 chr8:95922752 A/G cg13393036 chr8:95962371 TP53INP1 0.44 5.14 0.42 1.05e-6 Type 2 diabetes; TGCT cis rs2295359 0.824 rs11209003 chr1:67601132 G/T cg12940439 chr1:67600707 NA 0.64 6.74 0.52 5.26e-10 Psoriasis; TGCT cis rs875971 0.540 rs781152 chr7:65479572 T/A cg18876405 chr7:65276391 NA 0.4 6.37 0.5 3.34e-9 Aortic root size; TGCT cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs2404602 0.647 rs7181506 chr15:76935677 G/T cg22467129 chr15:76604101 ETFA -0.45 -4.49 -0.37 1.62e-5 Blood metabolite levels; TGCT cis rs9300255 0.739 rs1879380 chr12:123739111 G/A cg00376283 chr12:123451042 ABCB9 -0.73 -5.03 -0.41 1.69e-6 Neutrophil percentage of white cells; TGCT cis rs6840360 1.000 rs6535813 chr4:152599652 A/T cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs9914544 0.545 rs12452289 chr17:18781809 T/G cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.06e-6 Educational attainment (years of education); TGCT cis rs7909074 1.000 rs4948927 chr10:45397071 G/A cg05187965 chr10:45406764 TMEM72 -0.24 -5.23 -0.42 7.12e-7 Mean corpuscular volume; TGCT cis rs17376456 0.877 rs10065056 chr5:93380123 G/T cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg22029157 chr1:209979665 IRF6 0.76 6.32 0.49 4.37e-9 Cleft lip with or without cleft palate; TGCT cis rs12210905 0.925 rs858985 chr6:27178028 T/C cg08851530 chr6:28072375 NA -0.99 -4.79 -0.4 4.65e-6 Hip circumference adjusted for BMI; TGCT cis rs28595532 0.920 rs114653217 chr4:119769216 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs1505368 0.817 rs6435701 chr2:213283512 A/G cg20637307 chr2:213403960 ERBB4 0.51 4.84 0.4 3.75e-6 Symmetrical dimethylarginine levels; TGCT cis rs7818688 0.697 rs74633235 chr8:95981476 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs739496 0.615 rs57303367 chr12:112265083 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs2439831 0.867 rs2255440 chr15:43830467 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.98 7.56 0.56 7.97e-12 Lung cancer in ever smokers; TGCT cis rs425277 0.583 rs12059660 chr1:2041461 C/T cg24578937 chr1:2090814 PRKCZ -0.22 -5.19 -0.42 8.29e-7 Height; TGCT cis rs36093844 0.747 rs11234420 chr11:85528580 G/A cg25872744 chr11:85566296 CCDC83 -0.59 -5.04 -0.41 1.62e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs4819052 0.851 rs4819043 chr21:46660078 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.78 0.52 4.27e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs586688 0.625 rs609396 chr1:201655233 C/T cg14168733 chr1:201708718 NAV1 -0.55 -4.44 -0.37 1.93e-5 Obesity-related traits; TGCT cis rs3733585 0.673 rs6843873 chr4:9958788 A/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs597539 0.652 rs668576 chr11:68668208 A/G cg21862992 chr11:68658383 NA 0.47 6.61 0.51 1.03e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1008375 0.835 rs9760627 chr4:17651508 C/T cg18681998 chr4:17616180 MED28 1.06 12.08 0.74 1.11e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg26338869 chr17:61819248 STRADA -0.52 -4.79 -0.4 4.69e-6 Prudent dietary pattern; TGCT cis rs9549260 0.755 rs9549252 chr13:41230141 A/G cg21288729 chr13:41239152 FOXO1 0.98 10.47 0.69 9.04e-19 Red blood cell count; TGCT cis rs1577917 1.000 rs13199006 chr6:86608708 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs2836950 0.509 rs11088466 chr21:40580017 T/A cg17971929 chr21:40555470 PSMG1 -0.53 -4.74 -0.39 5.69e-6 Menarche (age at onset); TGCT cis rs3092073 0.617 rs3746513 chr20:44594228 G/A cg23252815 chr20:44420276 WFDC3;DNTTIP1 -0.27 -4.44 -0.37 1.93e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.593 rs16921589 chr8:58024387 C/A cg08280861 chr8:58055591 NA 0.36 5.16 0.42 9.31e-7 Developmental language disorder (linguistic errors); TGCT cis rs904251 0.861 rs2776877 chr6:37487135 G/A cg01843034 chr6:37503916 NA -0.52 -6.28 -0.49 5.17e-9 Cognitive performance; TGCT cis rs7772486 0.720 rs991507 chr6:146023609 G/A cg23711669 chr6:146136114 FBXO30 -0.95 -11.14 -0.71 2.17e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs751728 1.000 rs11752297 chr6:33735154 G/C cg13859433 chr6:33739653 LEMD2 -0.4 -7.63 -0.57 5.49e-12 Crohn's disease; TGCT cis rs2070488 0.775 rs2051214 chr3:38560303 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.64 -5.68 -0.45 9.01e-8 Electrocardiographic conduction measures; TGCT cis rs4803468 1.000 rs8105833 chr19:41896145 G/A cg09537434 chr19:41945824 ATP5SL -0.9 -10.06 -0.67 9.09e-18 Height; TGCT cis rs2729354 0.953 rs2848625 chr11:57330650 G/C cg24343310 chr11:57249947 NA 0.28 4.82 0.4 4.14e-6 Blood protein levels; TGCT cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs2070488 0.804 rs2268755 chr3:38501916 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.78 -7.9 -0.58 1.26e-12 Electrocardiographic conduction measures; TGCT cis rs1568889 1.000 rs12797689 chr11:28076042 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.85 9.04 0.63 2.64e-15 Bipolar disorder; TGCT cis rs9486719 1.000 rs2971603 chr6:97035418 C/T cg18709589 chr6:96969512 KIAA0776 -0.78 -6.38 -0.5 3.24e-9 Migraine;Coronary artery disease; TGCT cis rs7412746 0.634 rs4451553 chr1:150937329 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.55 0.38 1.26e-5 Melanoma; TGCT cis rs12142240 0.698 rs72890727 chr1:46860237 G/A cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs13256369 0.851 rs11786125 chr8:8564570 T/G cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs1577917 0.771 rs2475791 chr6:86368164 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs9291683 0.510 rs4318649 chr4:10016815 T/C cg11266682 chr4:10021025 SLC2A9 0.69 9.1 0.63 1.93e-15 Bone mineral density; TGCT cis rs2637266 0.678 rs2894345 chr10:78454561 A/C cg18941641 chr10:78392320 NA 0.4 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg23982607 chr1:1823379 GNB1 -0.55 -8.5 -0.61 5.16e-14 Body mass index; TGCT cis rs3849570 0.961 rs13340130 chr3:81790970 A/T cg07356753 chr3:81810745 GBE1 -0.85 -8.17 -0.59 3.06e-13 Waist circumference;Body mass index; TGCT cis rs1971762 0.527 rs4019971 chr12:53978715 A/G cg16917193 chr12:54089295 NA 0.89 9.11 0.63 1.74e-15 Height; TGCT cis rs7937682 1.000 rs11213973 chr11:111538903 A/T cg09085632 chr11:111637200 PPP2R1B -1.02 -9.74 -0.66 5.34e-17 Primary sclerosing cholangitis; TGCT cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Vitiligo; TGCT cis rs7829975 0.711 rs1039916 chr8:8685854 A/G cg06636001 chr8:8085503 FLJ10661 0.74 6.63 0.51 9.09e-10 Mood instability; TGCT cis rs9393777 0.513 rs7740197 chr6:26663478 C/T cg15659132 chr6:26577336 NA 0.74 5.21 0.42 7.65e-7 Intelligence (multi-trait analysis); TGCT cis rs6933660 0.720 rs6914656 chr6:151753421 C/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.76 0.39 5.36e-6 Menarche (age at onset); TGCT cis rs4478037 1.000 rs57477065 chr3:33162532 A/C cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs9611565 0.649 rs5758434 chr22:42116163 G/A cg03806693 chr22:41940476 POLR3H 0.96 9.91 0.66 2.06e-17 Vitiligo; TGCT cis rs2046867 0.908 rs62251634 chr3:72788705 A/C cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs12893668 0.572 rs2273175 chr14:104160141 T/C cg26031613 chr14:104095156 KLC1 -0.59 -5.05 -0.41 1.53e-6 Reticulocyte count; TGCT cis rs4918072 0.606 rs78381949 chr10:105612418 G/A cg11005552 chr10:105648138 OBFC1 0.39 4.73 0.39 6.1e-6 Coronary artery disease; TGCT cis rs4689388 0.889 rs4629534 chr4:6294124 G/T cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs28785552 0.769 rs28796114 chr19:53234319 T/C cg22067481 chr19:53234126 ZNF611 -0.51 -7.5 -0.56 1.09e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7523273 0.565 rs11118451 chr1:207887493 A/G cg22525895 chr1:207977042 MIR29B2 0.35 5.75 0.46 6.66e-8 Schizophrenia; TGCT cis rs7647973 0.593 rs58339610 chr3:49845006 T/A cg05785598 chr3:49045655 WDR6 -0.42 -5.32 -0.43 4.71e-7 Menarche (age at onset); TGCT cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg13607699 chr17:42295918 UBTF 0.84 7.5 0.56 1.05e-11 Total body bone mineral density; TGCT cis rs916888 0.697 rs199516 chr17:44856485 C/T cg05721485 chr17:44071124 MAPT -0.25 -4.58 -0.38 1.1e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4644046 0.545 rs10948626 chr6:51429680 A/G cg14391730 chr6:52021665 NA 0.31 4.46 0.37 1.8e-5 Coronary artery disease; TGCT cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs617219 0.765 rs10053349 chr5:78475423 T/C cg09550809 chr5:78407562 BHMT 0.4 5.75 0.46 6.44e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6570726 0.791 rs621382 chr6:145799144 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.74 0.39 5.78e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg20887711 chr4:1340912 KIAA1530 0.77 6.45 0.5 2.3e-9 Longevity; TGCT cis rs13082711 0.554 rs4973729 chr3:27390637 G/A cg02860705 chr3:27208620 NA 0.43 6.0 0.47 2.03e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs3087591 0.919 rs2952983 chr17:29470288 G/C cg24425628 chr17:29625626 OMG;NF1 0.44 6.44 0.5 2.39e-9 Hip circumference; TGCT cis rs654950 0.934 rs654220 chr1:42002556 A/T cg06885757 chr1:42089581 HIVEP3 -0.26 -4.6 -0.38 1.01e-5 Airway imaging phenotypes; TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg06873352 chr17:61820015 STRADA 0.54 5.91 0.47 3.07e-8 Prudent dietary pattern; TGCT cis rs7223966 1.000 rs6504182 chr17:61823672 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.08 0.42 1.34e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs858239 0.699 rs1881201 chr7:23194013 C/T cg05602783 chr7:23145260 KLHL7 0.65 5.75 0.46 6.52e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9926296 0.546 rs7187436 chr16:89845110 A/T cg03388025 chr16:89894329 SPIRE2 0.53 9.44 0.65 2.83e-16 Vitiligo; TGCT cis rs7666738 0.800 rs13106995 chr4:99028790 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9532580 0.778 rs61963319 chr13:41244220 A/T cg21288729 chr13:41239152 FOXO1 1.01 10.56 0.69 5.52e-19 Mean corpuscular hemoglobin; TGCT cis rs9913156 0.589 rs7213481 chr17:4547906 C/T cg00122941 chr17:4613640 ARRB2 0.87 7.39 0.55 1.89e-11 Lymphocyte counts; TGCT cis rs896854 0.846 rs2340584 chr8:95916811 A/G cg13393036 chr8:95962371 TP53INP1 -0.59 -8.02 -0.58 6.81e-13 Type 2 diabetes; TGCT cis rs36051895 0.632 rs2381213 chr9:5168871 A/G cg02405213 chr9:5042618 JAK2 0.67 8.11 0.59 4.24e-13 Pediatric autoimmune diseases; TGCT cis rs910316 0.763 rs6574205 chr14:75453039 G/C cg11812906 chr14:75593930 NEK9 0.58 5.61 0.45 1.23e-7 Height; TGCT cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg26818010 chr10:134567672 INPP5A -0.36 -4.99 -0.41 2e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2464469 0.526 rs11071363 chr15:58333961 A/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.39 -0.5 3.11e-9 Barrett's esophagus or Esophageal adenocarcinoma; TGCT cis rs6121246 0.559 rs6121038 chr20:30254773 T/G cg13852791 chr20:30311386 BCL2L1 0.78 7.1 0.54 8.37e-11 Mean corpuscular hemoglobin; TGCT cis rs6088580 0.601 rs6120668 chr20:33099793 A/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs1371867 0.846 rs1660317 chr8:101333252 G/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs896854 0.738 rs509594 chr8:95967156 C/G cg09323728 chr8:95962352 TP53INP1 0.45 5.26 0.43 6.17e-7 Type 2 diabetes; TGCT cis rs12765878 0.580 rs11191829 chr10:105614452 G/T cg11005552 chr10:105648138 OBFC1 -0.37 -5.91 -0.47 3.14e-8 Coronary artery disease; TGCT cis rs2013441 1.000 rs4924808 chr17:20026548 C/T cg13482628 chr17:19912719 NA -0.52 -4.48 -0.37 1.68e-5 Obesity-related traits; TGCT cis rs3008870 1.000 rs3008874 chr1:67431365 A/T cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg05890377 chr2:74357713 NA 0.44 5.15 0.42 9.84e-7 Gestational age at birth (maternal effect); TGCT cis rs9926296 0.527 rs1800335 chr16:89846195 A/G cg04287289 chr16:89883240 FANCA 0.92 11.5 0.72 2.84e-21 Vitiligo; TGCT cis rs7193541 0.965 rs4402594 chr16:74701360 C/T cg01733217 chr16:74700730 RFWD3 0.84 8.52 0.61 4.64e-14 Multiple myeloma; TGCT cis rs8032315 0.965 rs12906125 chr15:91427612 G/A cg06330618 chr15:91428456 FES 0.19 4.64 0.38 8.6e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7647973 0.925 rs4955423 chr3:49220448 G/A cg07636037 chr3:49044803 WDR6 0.63 5.09 0.42 1.27e-6 Menarche (age at onset); TGCT cis rs12477438 0.798 rs1349778 chr2:99645011 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.75 -0.46 6.58e-8 Chronic sinus infection; TGCT cis rs9910055 0.960 rs9911991 chr17:42278916 G/C cg19774624 chr17:42201019 HDAC5 -0.86 -8.52 -0.61 4.46e-14 Total body bone mineral density; TGCT cis rs55883249 1.000 rs10495571 chr2:9736066 A/G cg23886495 chr2:9695866 ADAM17 0.81 5.0 0.41 1.93e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1005277 0.579 rs2474580 chr10:38398713 G/A cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg18765753 chr7:1198926 ZFAND2A -0.48 -5.53 -0.44 1.83e-7 Longevity;Endometriosis; TGCT cis rs10504229 0.679 rs2218271 chr8:58052446 T/A cg08280861 chr8:58055591 NA 0.36 5.14 0.42 1.03e-6 Developmental language disorder (linguistic errors); TGCT cis rs9393692 0.905 rs6940237 chr6:26282322 T/C cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.14e-9 Educational attainment; TGCT cis rs877282 1.000 rs11253361 chr10:770387 T/C cg17470449 chr10:769945 NA 0.35 5.19 0.42 8.21e-7 Uric acid levels; TGCT cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg03264133 chr6:25882463 NA 0.74 7.71 0.57 3.43e-12 Blood metabolite levels; TGCT cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4919044 0.641 rs7914449 chr10:94723370 G/T cg05127821 chr10:94822908 CYP26C1 -0.73 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs2980439 0.517 rs17594093 chr8:8106406 G/T cg06636001 chr8:8085503 FLJ10661 -0.6 -4.98 -0.41 2.12e-6 Neuroticism; TGCT cis rs3008870 0.583 rs17497947 chr1:67457199 G/T cg11518657 chr1:67396239 MIER1 -0.6 -4.76 -0.39 5.32e-6 Lymphocyte percentage of white cells; TGCT cis rs910316 0.673 rs2012627 chr14:75443103 C/T cg11812906 chr14:75593930 NEK9 0.54 5.01 0.41 1.81e-6 Height; TGCT cis rs17253792 0.822 rs17746033 chr14:56061837 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs9309473 0.660 rs11686541 chr2:73704475 C/G cg07208825 chr2:73871855 ALMS1P 0.24 4.6 0.38 1.03e-5 Metabolite levels; TGCT cis rs9788682 0.694 rs3825845 chr15:78910258 C/T cg24631222 chr15:78858424 CHRNA5 0.92 6.59 0.51 1.11e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2797160 0.651 rs6939969 chr6:126034563 C/T cg05901451 chr6:126070800 HEY2 0.74 6.65 0.51 8.31e-10 Endometrial cancer; TGCT cis rs74181299 0.964 rs2540951 chr2:65276736 A/G cg05010058 chr2:65284262 CEP68 0.42 4.77 0.39 5.16e-6 Pulse pressure; TGCT cis rs7267979 1.000 rs4815424 chr20:25390284 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10489202 0.657 rs201540 chr1:167992883 G/A cg24449463 chr1:168025552 DCAF6 -0.6 -7.13 -0.54 7.21e-11 Schizophrenia; TGCT cis rs10509586 0.826 rs76962974 chr10:91898542 C/G cg25278353 chr10:91717815 NA 0.49 4.67 0.39 7.77e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs4722585 0.764 rs4259314 chr7:26182214 A/G cg03781084 chr7:26191726 NFE2L3 0.5 5.37 0.43 3.81e-7 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs5757676 0.858 rs6001585 chr22:39812986 G/T cg01416388 chr22:39784598 NA -0.78 -6.72 -0.52 5.79e-10 IgG glycosylation; TGCT cis rs9527 0.590 rs10786741 chr10:104939182 G/A cg15744005 chr10:104629667 AS3MT -0.4 -4.59 -0.38 1.08e-5 Arsenic metabolism; TGCT cis rs798554 0.679 rs798499 chr7:2792013 G/A cg25467336 chr7:2757616 NA -0.24 -4.71 -0.39 6.54e-6 Height; TGCT cis rs903263 0.965 rs7515976 chr1:84627743 T/G cg09664975 chr1:84543551 PRKACB 0.48 4.54 0.38 1.31e-5 Breast cancer (male); TGCT cis rs2153535 0.580 rs2184582 chr6:8447793 G/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs4665809 1.000 rs11678157 chr2:26321526 T/C cg22920501 chr2:26401640 FAM59B -0.72 -6.2 -0.49 7.73e-9 Gut microbiome composition (summer); TGCT trans rs7819412 0.775 rs11773990 chr8:10935082 T/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.07 -0.54 1.01e-10 Triglycerides; TGCT cis rs1997103 1.000 rs6593238 chr7:55411048 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs921968 0.541 rs3821031 chr2:219295249 C/T cg02176678 chr2:219576539 TTLL4 -0.46 -6.55 -0.51 1.36e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs7822232 0.908 rs6558295 chr8:145139522 C/G cg26272248 chr8:145163034 KIAA1875 -0.49 -4.81 -0.4 4.24e-6 Blood metabolite levels; TGCT cis rs12497850 0.863 rs4858799 chr3:48728204 G/C cg06212747 chr3:49208901 KLHDC8B 0.62 5.94 0.47 2.65e-8 Parkinson's disease; TGCT cis rs2120019 0.938 rs8033925 chr15:75311959 A/G cg09165964 chr15:75287851 SCAMP5 -1.14 -10.33 -0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs7226408 0.857 rs72887044 chr18:34481573 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs637571 0.565 rs633800 chr11:65638719 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.61 -6.31 -0.49 4.43e-9 Eosinophil percentage of white cells; TGCT cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs4455778 0.580 rs6944916 chr7:49113732 T/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs6582630 0.537 rs11520294 chr12:38402705 C/A cg13010199 chr12:38710504 ALG10B 0.61 4.82 0.4 4.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2115630 1.000 rs11854291 chr15:85363708 T/C cg12501888 chr15:85177176 SCAND2 -0.47 -4.45 -0.37 1.91e-5 P wave terminal force; TGCT cis rs17102423 0.755 rs8009396 chr14:65573438 C/G cg11161011 chr14:65562177 MAX -0.54 -7.49 -0.56 1.15e-11 Obesity-related traits; TGCT cis rs7267979 1.000 rs6050547 chr20:25326012 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3015497 0.789 rs7147956 chr14:51142605 G/A cg04730355 chr14:51134070 SAV1 -0.67 -6.4 -0.5 2.96e-9 Mean platelet volume; TGCT cis rs858239 0.601 rs15775 chr7:23164701 C/T cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT trans rs3780486 0.505 rs7868663 chr9:33141229 A/G cg20290983 chr6:43655470 MRPS18A 0.78 8.34 0.6 1.23e-13 IgG glycosylation; TGCT cis rs7949030 0.620 rs2428551 chr11:62329758 T/A cg13298116 chr11:62369859 EML3;MTA2 0.63 9.54 0.65 1.64e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs425277 1.000 rs262654 chr1:2089526 G/A cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs7104764 0.701 rs3782115 chr11:223272 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.0 9.93 0.67 1.92e-17 Menarche (age at onset); TGCT cis rs6582630 0.502 rs11520234 chr12:38255005 G/A cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9902453 0.902 rs4075014 chr17:28305674 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 6.61 0.51 1.02e-9 Coffee consumption (cups per day); TGCT cis rs56091001 0.528 rs9616387 chr22:50313219 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -5.95 -0.47 2.57e-8 Acne (severe); TGCT cis rs634534 0.562 rs1151505 chr11:65734539 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.56 5.43 0.44 2.87e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs4523957 0.651 rs898748 chr17:2085475 G/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12477438 0.765 rs10181344 chr2:99692829 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs3770081 1.000 rs2164879 chr2:86261579 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.18 -4.81 -0.4 4.33e-6 Facial emotion recognition (sad faces); TGCT cis rs9926296 0.605 rs6500449 chr16:89856393 T/C cg03388025 chr16:89894329 SPIRE2 0.5 8.7 0.62 1.73e-14 Vitiligo; TGCT trans rs6089829 0.962 rs9680064 chr20:61666168 G/A cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs601339 1.000 rs630408 chr12:123172822 C/T cg11919336 chr12:123188078 GPR109A 0.64 7.49 0.56 1.1e-11 Adiponectin levels; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg27535305 chr1:53392650 SCP2 -0.24 -4.69 -0.39 6.96e-6 Monocyte count; TGCT cis rs111544199 1 rs111544199 chr19:50091221 GT/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.65 0.45 1.02e-7 Red blood cell count; TGCT trans rs7618501 0.633 rs2883057 chr3:49998282 C/T cg21659725 chr3:3221576 CRBN 0.76 9.03 0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.53 4.78 0.39 4.77e-6 Colorectal cancer; TGCT cis rs727563 0.593 rs132770 chr22:42017264 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.12 0.42 1.13e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs739496 0.615 rs886205 chr12:112204427 A/G cg10833066 chr12:111807467 FAM109A 0.35 5.18 0.42 8.83e-7 Platelet count; TGCT cis rs6088590 1.000 rs6120748 chr20:33458284 T/G cg06115741 chr20:33292138 TP53INP2 0.64 5.1 0.42 1.25e-6 Coronary artery disease; TGCT cis rs651907 0.535 rs34263427 chr3:101507805 A/G cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs7267979 1.000 rs2424713 chr20:25418482 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2180341 1.000 rs6910763 chr6:127630925 T/C cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs7586879 0.520 rs6718511 chr2:25122324 A/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs9467773 1.000 rs3736782 chr6:26505403 C/A cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.523 rs11762152 chr7:106811374 G/A cg02696742 chr7:106810147 HBP1 -0.71 -6.08 -0.48 1.38e-8 Coronary artery disease; TGCT cis rs4076764 0.846 rs12036398 chr1:163422204 C/T cg24596788 chr1:163392923 NA 0.17 4.87 0.4 3.33e-6 Motion sickness; TGCT cis rs6089584 0.927 rs1886007 chr20:60581049 G/A cg13770153 chr20:60521292 NA -0.53 -7.22 -0.54 4.51e-11 Body mass index; TGCT cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg05368731 chr17:41323189 NBR1 1.1 11.08 0.71 2.94e-20 Menopause (age at onset); TGCT cis rs3764400 0.564 rs1452663 chr17:46293386 C/G cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs4665809 1.000 rs13030858 chr2:26315451 G/A cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs910316 0.967 rs1071989 chr14:75564659 G/T cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs74233809 1.000 rs12220375 chr10:104901491 T/C cg05855489 chr10:104503620 C10orf26 0.85 4.45 0.37 1.88e-5 Birth weight; TGCT cis rs849898 1 rs849898 chr1:228153917 A/G cg18477163 chr1:228402036 OBSCN -0.3 -5.68 -0.45 9.15e-8 Parkinson's disease; TGCT cis rs17102423 0.661 rs45604339 chr14:65543102 C/T cg11161011 chr14:65562177 MAX -0.55 -7.71 -0.57 3.47e-12 Obesity-related traits; TGCT cis rs858239 1.000 rs156421 chr7:23312487 A/G cg05602783 chr7:23145260 KLHL7 -0.58 -4.81 -0.4 4.35e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4654899 0.758 rs2874367 chr1:21324491 A/C cg01072550 chr1:21505969 NA 0.57 9.37 0.64 4.22e-16 Superior frontal gyrus grey matter volume; TGCT cis rs7178572 0.568 rs4243045 chr15:77455914 A/C cg22256960 chr15:77711686 NA -0.89 -8.95 -0.63 4.29e-15 Type 2 diabetes; TGCT cis rs910316 1.000 rs1047418 chr14:75605792 A/G cg08847533 chr14:75593920 NEK9 0.95 10.55 0.69 5.78e-19 Height; TGCT cis rs801193 1.000 rs3778909 chr7:66255646 G/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 8.09e-7 Aortic root size; TGCT trans rs35851103 0.506 rs4841659 chr8:11828200 C/T cg15556689 chr8:8085844 FLJ10661 0.87 7.83 0.58 1.91e-12 Neuroticism; TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg08859206 chr1:53392774 SCP2 -0.45 -7.07 -0.54 1.01e-10 Monocyte count; TGCT cis rs11024102 0.830 rs11024110 chr11:17028390 T/A cg15378786 chr11:17036137 PLEKHA7 0.49 4.72 0.39 6.17e-6 Glaucoma (primary angle closure); TGCT cis rs10875746 0.903 rs10875740 chr12:48489117 C/T cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs3734905 1.000 rs16888119 chr6:169937237 C/T cg20469989 chr6:170102314 C6orf120;WDR27 -0.88 -4.67 -0.39 7.59e-6 HIV-1 control; TGCT cis rs7017914 0.902 rs35580034 chr8:71572073 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs17376456 0.569 rs6881815 chr5:93105666 A/G cg25358565 chr5:93447407 FAM172A 0.76 6.68 0.51 7.23e-10 Diabetic retinopathy; TGCT cis rs13191362 1.000 rs35818596 chr6:163001874 C/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.544 rs58827325 chr2:219415166 A/T cg02176678 chr2:219576539 TTLL4 0.48 6.86 0.52 2.94e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs10992471 0.756 rs7027595 chr9:95131553 C/T cg14631576 chr9:95140430 CENPP -0.3 -4.88 -0.4 3.25e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs185694 0.857 rs200511 chr13:30904316 G/A cg07600127 chr13:30881527 KATNAL1 -0.54 -4.7 -0.39 6.94e-6 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs6901250 0.788 rs571296 chr6:117092558 A/G cg12892004 chr6:117198278 RFX6 -0.51 -6.28 -0.49 5.29e-9 C-reactive protein levels; TGCT cis rs7772486 0.840 rs854144 chr6:146360880 G/T cg23711669 chr6:146136114 FBXO30 -0.68 -6.49 -0.5 1.9e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2204008 0.744 rs8186814 chr12:38335169 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs7681440 0.804 rs763443 chr4:90819961 T/C cg14346243 chr4:90757452 SNCA -0.47 -4.54 -0.38 1.3e-5 Dementia with Lewy bodies; TGCT cis rs2898681 0.519 rs6848200 chr4:53730181 A/G cg00791764 chr4:53727839 RASL11B 0.54 4.58 0.38 1.1e-5 Optic nerve measurement (cup area); TGCT trans rs561341 0.883 rs886224 chr17:30229902 T/C cg20587970 chr11:113659929 NA -0.82 -9.73 -0.66 5.87e-17 Hip circumference adjusted for BMI; TGCT cis rs12220238 0.818 rs115350439 chr10:75899365 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs7267979 0.966 rs6083818 chr20:25346082 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs916888 0.773 rs199448 chr17:44809001 A/G cg01570182 chr17:44337453 NA 1.07 10.3 0.68 2.41e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs909674 0.515 rs9611170 chr22:39784845 G/C cg11247378 chr22:39784982 NA -0.76 -10.63 -0.69 3.71e-19 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7666738 0.606 rs13108868 chr4:99083753 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs881375 0.935 rs7034390 chr9:123646488 A/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.55 0.38 1.25e-5 Rheumatoid arthritis; TGCT cis rs2346177 0.519 rs1597040 chr2:46673903 C/T cg26688816 chr2:46740690 ATP6V1E2 -0.44 -4.77 -0.39 5.08e-6 HDL cholesterol; TGCT cis rs11190604 1.000 rs7477246 chr10:102261538 C/T cg16342193 chr10:102329863 NA -0.38 -4.89 -0.4 3.06e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6088580 0.601 rs6059827 chr20:33016358 C/T cg24642439 chr20:33292090 TP53INP2 0.49 4.57 0.38 1.16e-5 Glomerular filtration rate (creatinine); TGCT cis rs10789285 0.681 rs2248775 chr1:69697308 G/T ch.1.69469992R chr1:69697404 NA 0.31 4.52 0.38 1.4e-5 Psoriasis; TGCT cis rs9303401 0.659 rs17222523 chr17:56620501 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs6121246 0.738 rs2376996 chr20:30316667 T/A cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs2404602 0.647 rs7178250 chr15:77099107 T/C cg23625390 chr15:77176239 SCAPER -0.38 -4.83 -0.4 4.01e-6 Blood metabolite levels; TGCT cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs2404602 0.692 rs12437733 chr15:77155562 A/G cg22467129 chr15:76604101 ETFA -0.47 -5.3 -0.43 5.08e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs13149346 chr4:99009933 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs61931739 0.500 rs11053217 chr12:34470036 A/C cg06521331 chr12:34319734 NA -0.26 -4.45 -0.37 1.87e-5 Morning vs. evening chronotype; TGCT cis rs2836974 0.897 rs34599551 chr21:40594898 C/A cg11644478 chr21:40555479 PSMG1 1.0 10.51 0.69 7.16e-19 Cognitive function; TGCT cis rs4888262 0.507 rs9888976 chr16:74580924 C/T cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 7.94e-11 Testicular germ cell tumor; TGCT cis rs477895 0.713 rs1059440 chr11:63991801 C/T cg04317338 chr11:64019027 PLCB3 -0.82 -6.85 -0.52 3.06e-10 Mean platelet volume; TGCT cis rs1775715 0.737 rs55859032 chr10:32213239 C/T cg14930904 chr10:32216787 ARHGAP12 0.54 5.3 0.43 5.12e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs6952808 0.594 rs3778965 chr7:2138296 G/A cg04267008 chr7:1944627 MAD1L1 -0.36 -4.82 -0.4 4.05e-6 Bipolar disorder and schizophrenia; TGCT cis rs3617 0.625 rs2240915 chr3:52859526 T/A cg11645453 chr3:52864694 ITIH4 0.28 5.45 0.44 2.63e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4819052 1.000 rs9984901 chr21:46663952 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.76 6.02 0.48 1.8e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9926296 0.744 rs154656 chr16:89708003 T/A cg03388025 chr16:89894329 SPIRE2 -0.34 -5.15 -0.42 9.94e-7 Vitiligo; TGCT cis rs12510870 0.599 rs1528916 chr4:74452469 C/A cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs594074 0.951 rs581403 chr6:6556120 C/T cg03251356 chr6:7151709 RREB1 -0.3 -4.82 -0.4 4.09e-6 Diabetic kidney disease; TGCT cis rs5009270 0.524 rs11763427 chr7:112162843 C/T cg06717068 chr7:111370856 DOCK4 -0.25 -4.49 -0.37 1.61e-5 Osteoarthritis (hip); TGCT cis rs6088580 0.634 rs4258875 chr20:32924895 C/A cg08999081 chr20:33150536 PIGU -0.25 -4.85 -0.4 3.66e-6 Glomerular filtration rate (creatinine); TGCT cis rs10501293 0.746 rs10742662 chr11:43005385 A/G cg03447554 chr11:43094025 NA 0.45 6.36 0.5 3.57e-9 Cognitive performance; TGCT cis rs6424115 0.867 rs11588187 chr1:24145047 T/A cg15997130 chr1:24165203 NA 0.89 9.81 0.66 3.7e-17 Immature fraction of reticulocytes; TGCT cis rs1385374 0.858 rs10847697 chr12:129299385 C/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs7772486 0.837 rs2474354 chr6:146323795 T/A cg23711669 chr6:146136114 FBXO30 0.77 8.1 0.59 4.35e-13 Lobe attachment (rater-scored or self-reported); TGCT cis rs7937682 0.855 rs539553 chr11:111477333 C/T cg09085632 chr11:111637200 PPP2R1B -1.06 -11.27 -0.71 1.04e-20 Primary sclerosing cholangitis; TGCT cis rs6671200 0.790 rs640527 chr1:95705615 G/A cg20701556 chr1:95698924 RWDD3 -0.67 -5.63 -0.45 1.13e-7 Stearic acid (18:0) levels; TGCT trans rs1496653 0.602 rs13065375 chr3:23526686 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs7659604 0.502 rs13106764 chr4:122699630 C/G cg06713675 chr4:122721982 EXOSC9 0.37 4.61 0.38 9.99e-6 Type 2 diabetes; TGCT trans rs3780486 0.718 rs7859454 chr9:33119583 T/A cg20290983 chr6:43655470 MRPS18A 1.01 7.36 0.55 2.25e-11 IgG glycosylation; TGCT cis rs3820068 0.608 rs12760450 chr1:16037282 G/A cg17385448 chr1:15911702 AGMAT 0.37 4.98 0.41 2.06e-6 Systolic blood pressure; TGCT cis rs36051895 0.695 rs7851556 chr9:5022807 C/T cg02405213 chr9:5042618 JAK2 -0.8 -11.04 -0.7 3.76e-20 Pediatric autoimmune diseases; TGCT trans rs2727020 0.619 rs1164665 chr11:49295630 T/C cg15704280 chr7:45808275 SEPT13 0.67 6.8 0.52 4.02e-10 Coronary artery disease; TGCT cis rs6815814 0.950 rs5743556 chr4:38806851 A/G cg02016764 chr4:38805732 TLR1 -0.35 -5.58 -0.45 1.44e-7 Breast cancer; TGCT cis rs933688 1.000 rs933688 chr5:90762748 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.16 0.59 3.2e-13 Smoking behavior; TGCT cis rs929354 0.772 rs10228145 chr7:157007337 A/G cg05182265 chr7:156933206 UBE3C -0.37 -8.69 -0.62 1.8e-14 Body mass index; TGCT cis rs11031096 0.678 rs17284356 chr11:4189232 G/C cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9467711 0.606 rs4634439 chr6:26598004 C/T cg16898833 chr6:26189333 HIST1H4D -1.02 -5.25 -0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6089829 0.962 rs3746749 chr20:61667333 T/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT trans rs7726839 0.540 rs72703079 chr5:595173 T/C cg11887960 chr12:57824829 NA 1.2 9.65 0.65 8.99e-17 Obesity-related traits; TGCT cis rs9633740 1.000 rs10749609 chr10:82249752 G/A cg01528321 chr10:82214614 TSPAN14 0.96 8.21 0.59 2.39e-13 Post bronchodilator FEV1; TGCT cis rs2456568 0.802 rs7101791 chr11:93638998 A/G cg17595323 chr11:93583763 C11orf90 -0.47 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1670533 1.000 rs10084889 chr4:1053815 G/A cg20887711 chr4:1340912 KIAA1530 0.7 5.65 0.45 1.03e-7 Recombination rate (females); TGCT cis rs1008375 1.000 rs10939749 chr4:17692319 A/C cg18681998 chr4:17616180 MED28 0.76 7.28 0.55 3.42e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs910316 0.967 rs175498 chr14:75536369 G/A cg11812906 chr14:75593930 NEK9 -0.73 -7.08 -0.54 9.58e-11 Height; TGCT cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg21672276 chr3:44754072 ZNF502 -0.45 -5.06 -0.41 1.47e-6 Depressive symptoms; TGCT cis rs6988636 1.000 rs4377946 chr8:124185887 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg25767906 chr1:53392781 SCP2 -0.57 -6.53 -0.51 1.55e-9 Monocyte count; TGCT cis rs11190604 1.000 rs10883497 chr10:102228519 A/G cg07570687 chr10:102243282 WNT8B 0.31 4.61 0.38 9.72e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs877282 0.838 rs11253374 chr10:774961 C/T cg17470449 chr10:769945 NA 0.31 5.08 0.42 1.34e-6 Uric acid levels; TGCT cis rs651907 0.535 rs13085776 chr3:101505507 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.76 9.11 0.63 1.77e-15 Colorectal cancer; TGCT cis rs28595532 0.920 rs115430947 chr4:119737149 C/A cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs72781680 0.699 rs72794291 chr2:23897935 C/T cg08917208 chr2:24149416 ATAD2B 1.0 5.56 0.45 1.59e-7 Lymphocyte counts; TGCT trans rs11662586 0.517 rs7230837 chr18:77695384 A/T cg05926928 chr17:57297772 GDPD1 0.77 7.85 0.58 1.71e-12 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs10751667 1.000 rs11246359 chr11:967943 T/C cg06064525 chr11:970664 AP2A2 -0.33 -6.52 -0.51 1.62e-9 Alzheimer's disease (late onset); TGCT cis rs1691799 0.867 rs1168297 chr12:66735644 T/C cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg07061783 chr6:25882402 NA -0.57 -5.44 -0.44 2.74e-7 Intelligence (multi-trait analysis); TGCT cis rs3749237 0.595 rs11130196 chr3:49490149 A/C cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs9457247 0.646 rs4710160 chr6:167409241 T/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs11711311 0.824 rs9833810 chr3:113363762 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.69 -5.83 -0.46 4.49e-8 IgG glycosylation; TGCT cis rs6684514 1.000 rs11264467 chr1:156273061 A/G cg16558208 chr1:156270281 VHLL -0.47 -8.77 -0.62 1.16e-14 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6835098 0.692 rs1316411 chr4:174075143 A/G cg08422745 chr4:174089978 GALNT7 -0.77 -8.6 -0.61 2.87e-14 Dementia and core Alzheimer's disease neuropathologic changes; TGCT trans rs7618501 1.000 rs7372730 chr3:49790682 C/G cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs73001065 0.636 rs28720066 chr19:19572220 G/T cg03709012 chr19:19516395 GATAD2A 0.9 4.77 0.39 5.17e-6 LDL cholesterol; TGCT cis rs7552404 0.731 rs10873808 chr1:76406767 T/C cg10523679 chr1:76189770 ACADM 0.85 7.56 0.56 7.7e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs67311347 0.910 rs13089215 chr3:40495894 T/C cg13683864 chr3:40499215 RPL14 1.12 10.58 0.69 4.95e-19 Renal cell carcinoma; TGCT cis rs1843834 0.505 rs940317 chr2:225358118 C/T cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs244731 0.919 rs12652509 chr5:176626441 A/G cg06060754 chr5:176797920 RGS14 -0.44 -6.2 -0.49 7.79e-9 Urate levels in lean individuals; TGCT cis rs7909074 0.933 rs879073 chr10:45399882 C/G cg05187965 chr10:45406764 TMEM72 -0.23 -4.88 -0.4 3.25e-6 Mean corpuscular volume; TGCT cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg17554472 chr22:41940697 POLR3H -0.47 -5.04 -0.41 1.63e-6 Vitiligo; TGCT cis rs7216064 1.000 rs62084248 chr17:65874541 C/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2760061 0.583 rs708124 chr1:228220771 A/T cg02753203 chr1:228287806 NA 0.4 8.32 0.6 1.31e-13 Diastolic blood pressure; TGCT cis rs11105298 0.838 rs4842488 chr12:89881564 C/G cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs739496 0.615 rs12582964 chr12:112090779 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.1 0.42 1.23e-6 Platelet count; TGCT cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs3026101 0.671 rs3026115 chr17:5285222 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.46 4.52 0.38 1.45e-5 Body mass index; TGCT cis rs1514658 0.868 rs13145902 chr4:119282478 C/A cg21605333 chr4:119757512 SEC24D -0.5 -4.53 -0.38 1.35e-5 Congenital heart disease (maternal effect); TGCT cis rs477895 0.838 rs2001003 chr11:64018687 C/A cg04317338 chr11:64019027 PLCB3 0.81 6.9 0.53 2.35e-10 Mean platelet volume; TGCT cis rs3820928 1.000 rs61067328 chr2:227761256 G/A cg11843606 chr2:227700838 RHBDD1 -0.51 -4.51 -0.38 1.47e-5 Pulmonary function; TGCT cis rs933688 1.000 rs10045280 chr5:90717675 T/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.18 0.59 2.89e-13 Smoking behavior; TGCT cis rs9921338 0.961 rs72773833 chr16:11413274 G/A cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs12579753 0.872 rs7956132 chr12:82178709 A/G cg07988820 chr12:82153109 PPFIA2 -0.55 -5.63 -0.45 1.14e-7 Resting heart rate; TGCT cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg11890956 chr21:40555474 PSMG1 -0.76 -7.45 -0.56 1.39e-11 Cognitive function; TGCT cis rs13191362 1.000 rs68144677 chr6:163149024 T/C cg06582575 chr6:163149167 PACRG;PARK2 1.0 7.73 0.57 3.24e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11030122 0.604 rs10835557 chr11:4083121 A/G cg18678763 chr11:4115507 RRM1 -0.48 -5.88 -0.47 3.49e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs4727027 0.901 rs6944781 chr7:148829566 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs11167764 0.945 rs891991 chr5:141484977 A/T cg23435118 chr5:141488016 NDFIP1 -0.3 -5.11 -0.42 1.18e-6 Crohn's disease; TGCT cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg11644478 chr21:40555479 PSMG1 0.96 9.75 0.66 5.14e-17 Cognitive function; TGCT cis rs62064224 0.902 rs35830939 chr17:30627564 A/C cg18200150 chr17:30822561 MYO1D 0.45 5.93 0.47 2.82e-8 Schizophrenia; TGCT cis rs9372253 0.967 rs9400379 chr6:110713783 A/G cg19196401 chr6:110721138 DDO -0.47 -6.8 -0.52 4e-10 Platelet distribution width; TGCT cis rs9677476 0.632 rs6437008 chr2:232091948 C/G cg07929768 chr2:232055508 NA 0.35 5.57 0.45 1.49e-7 Food antigen IgG levels; TGCT trans rs1005277 0.579 rs2474574 chr10:38387295 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs17376456 0.877 rs10035340 chr5:93490465 C/T cg21475434 chr5:93447410 FAM172A 0.63 4.63 0.38 8.98e-6 Diabetic retinopathy; TGCT cis rs9486719 0.790 rs2499790 chr6:96845078 G/A cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs4478037 1.000 rs4074415 chr3:33161745 A/G cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs10514758 0.590 rs16823509 chr3:114836254 T/C cg05943254 chr3:114009756 NA -0.85 -5.06 -0.41 1.48e-6 Urate levels in obese individuals; TGCT cis rs72945132 0.598 rs61887433 chr11:70240997 A/G cg00319359 chr11:70116639 PPFIA1 1.0 7.01 0.53 1.35e-10 Coronary artery disease; TGCT cis rs9467773 0.609 rs12663780 chr6:26397573 T/C cg05738196 chr6:26577821 NA -0.48 -4.94 -0.41 2.51e-6 Intelligence (multi-trait analysis); TGCT cis rs6671200 0.607 rs2147587 chr1:95714884 G/A cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT trans rs208515 0.525 rs12215007 chr6:66671008 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.9 -9.83 -0.66 3.19e-17 Exhaled nitric oxide levels; TGCT cis rs6854137 0.553 rs17614715 chr4:169701578 A/T cg20607169 chr4:169750834 PALLD -0.2 -4.48 -0.37 1.66e-5 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs6671200 0.790 rs640527 chr1:95705615 G/A cg26537280 chr1:95699037 RWDD3 -0.7 -5.55 -0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs17155006 0.651 rs416811 chr7:107724047 G/C cg05962710 chr7:107745446 LAMB4 -0.19 -4.75 -0.39 5.44e-6 Pneumococcal bacteremia; TGCT cis rs7095607 0.606 rs4746739 chr10:69960091 C/T cg18986048 chr10:69913749 MYPN -0.56 -5.87 -0.47 3.81e-8 Lung function (FVC); TGCT cis rs7428 0.924 rs908304 chr2:85573049 G/A cg24342717 chr2:85555507 TGOLN2 -0.4 -6.41 -0.5 2.78e-9 Ear protrusion; TGCT cis rs6430585 0.528 rs309162 chr2:136690783 T/A cg07169764 chr2:136633963 MCM6 1.26 12.74 0.75 2.79e-24 Corneal structure; TGCT cis rs9611519 0.894 rs9611488 chr22:41462592 G/T cg13695892 chr22:41940480 POLR3H -0.54 -4.79 -0.39 4.76e-6 Neuroticism; TGCT cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2688608 0.592 rs7923045 chr10:75487498 A/T cg17411546 chr10:75410026 SYNPO2L -0.46 -4.51 -0.38 1.51e-5 Inflammatory bowel disease; TGCT cis rs4443100 0.670 rs9608071 chr22:23408118 G/T cg14186256 chr22:23484241 RTDR1 0.61 4.89 0.4 3.03e-6 Serum parathyroid hormone levels; TGCT cis rs7666738 0.830 rs10007261 chr4:98926155 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.954 rs9685777 chr4:120365965 C/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs1023500 0.596 rs5751209 chr22:42451603 A/G cg05082376 chr22:42548792 NA -0.22 -5.29 -0.43 5.32e-7 Schizophrenia; TGCT cis rs12118280 0.612 rs591141 chr1:108694894 A/G cg11967332 chr1:108735228 SLC25A24 0.35 5.17 0.42 9.01e-7 Myeloid white cell count; TGCT cis rs11030122 0.673 rs66596383 chr11:3979745 C/T cg18678763 chr11:4115507 RRM1 -0.47 -5.82 -0.46 4.73e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs17767294 0.708 rs72848792 chr6:27997656 A/G cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs6840360 0.582 rs59714108 chr4:152325939 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.68e-9 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.05 -9.36 -0.64 4.35e-16 Platelet count; TGCT cis rs7225537 0.532 rs11551189 chr17:17062241 C/G cg26176665 chr17:16994978 MPRIP 0.23 5.3 0.43 5.11e-7 Mean platelet volume; TGCT cis rs2795502 0.873 rs2795527 chr10:43270240 T/C cg20628663 chr10:43360327 NA -0.41 -4.81 -0.4 4.3e-6 Blood protein levels; TGCT cis rs367943 1.000 rs191553 chr5:112823659 A/G cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs7772486 0.754 rs6906258 chr6:146089356 A/G cg13319975 chr6:146136371 FBXO30 0.58 5.29 0.43 5.27e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2708977 0.842 rs10209780 chr2:97140142 T/G cg01950434 chr2:97203154 ARID5A -0.68 -6.22 -0.49 7.09e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs2458413 0.564 rs2669452 chr8:105370385 C/A cg04554929 chr8:105342491 NA 0.48 5.77 0.46 5.95e-8 Paget's disease; TGCT cis rs7523273 0.853 rs7537216 chr1:208006429 A/T cg22525895 chr1:207977042 MIR29B2 -0.48 -8.33 -0.6 1.26e-13 Schizophrenia; TGCT cis rs9640161 0.750 rs11764936 chr7:150025915 G/T cg10018233 chr7:150070692 REPIN1 0.33 4.81 0.4 4.35e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs992157 0.560 rs7605980 chr2:219100869 C/G cg00012203 chr2:219082015 ARPC2 0.81 9.56 0.65 1.49e-16 Colorectal cancer; TGCT cis rs709400 0.628 rs2010281 chr14:103862322 G/A cg26031613 chr14:104095156 KLC1 0.85 9.32 0.64 5.53e-16 Body mass index; TGCT cis rs950169 0.580 rs11634322 chr15:85172209 C/T cg11189052 chr15:85197271 WDR73 0.73 6.01 0.47 1.96e-8 Schizophrenia; TGCT cis rs3749237 0.595 rs6784820 chr3:49450864 C/T cg07636037 chr3:49044803 WDR6 -0.63 -6.05 -0.48 1.56e-8 Resting heart rate; TGCT cis rs4499344 0.633 rs411328 chr19:33140178 T/G cg26639809 chr19:33781782 NA 0.22 4.64 0.38 8.84e-6 Mean platelet volume; TGCT cis rs11214589 0.651 rs17600713 chr11:113259947 C/T cg14159747 chr11:113255604 NA 0.36 4.67 0.39 7.63e-6 Neuroticism; TGCT cis rs9300255 0.602 rs11057192 chr12:123693420 T/C cg00376283 chr12:123451042 ABCB9 0.72 5.66 0.45 1.01e-7 Neutrophil percentage of white cells; TGCT cis rs4975709 0.798 rs4975757 chr5:1882579 G/A cg14773178 chr5:1868261 NA 0.35 4.7 0.39 6.74e-6 Cardiovascular disease risk factors; TGCT cis rs1580019 0.563 rs13244332 chr7:32537679 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.58 5.0 0.41 1.94e-6 Cognitive ability; TGCT cis rs8103278 0.507 rs10401971 chr19:46261982 C/T cg11657440 chr19:46296263 DMWD 0.74 7.77 0.57 2.62e-12 Coronary artery disease; TGCT cis rs889312 0.500 rs702691 chr5:56114526 T/G cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs2204008 0.606 rs6582502 chr12:38543352 C/T cg26384229 chr12:38710491 ALG10B -0.53 -4.75 -0.39 5.51e-6 Bladder cancer; TGCT cis rs295140 0.605 rs159321 chr2:201184713 C/T cg04283868 chr2:201171347 SPATS2L 0.47 4.57 0.38 1.14e-5 QT interval; TGCT cis rs72781680 1.000 rs72796339 chr2:24143063 T/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs7726839 0.540 rs3762951 chr5:662613 C/G cg16624210 chr5:671434 TPPP 0.4 4.66 0.39 8.03e-6 Obesity-related traits; TGCT cis rs9467773 0.935 rs9461270 chr6:26544110 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.48 0.5 1.95e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs3846443 chr4:99032666 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.42 0.55 1.62e-11 Schizophrenia; TGCT cis rs9853921 0.674 rs9843822 chr3:117966792 G/A cg15509235 chr3:117715573 NA -0.53 -4.51 -0.38 1.46e-5 JT interval (sulfonylurea treatment interaction); TGCT trans rs2727020 0.635 rs7124266 chr11:49280857 T/G cg03929089 chr4:120376271 NA 0.72 8.01 0.58 7.19e-13 Coronary artery disease; TGCT cis rs751728 0.588 rs7774620 chr6:33736285 T/A cg13859433 chr6:33739653 LEMD2 -0.32 -5.93 -0.47 2.78e-8 Crohn's disease; TGCT cis rs4953076 0.573 rs7595470 chr2:44402467 A/G cg04920474 chr2:44395004 PPM1B 0.57 5.6 0.45 1.29e-7 Height; TGCT cis rs11122272 0.735 rs2572251 chr1:231514243 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs9549260 0.755 rs17061491 chr13:41228210 T/A cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs3617 0.573 rs9825230 chr3:52901974 G/A cg11645453 chr3:52864694 ITIH4 0.26 4.95 0.41 2.34e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3772130 0.926 rs13072767 chr3:121504098 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs7666738 0.800 rs1559858 chr4:99024075 A/G cg05340658 chr4:99064831 C4orf37 0.51 5.75 0.46 6.42e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13424612 0.930 rs4149545 chr2:240942818 G/T cg26363272 chr2:240904871 NDUFA10 0.28 4.79 0.4 4.65e-6 Odorant perception (isobutyraldehyde); TGCT cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs57994353 0.897 rs66477686 chr9:139372224 T/C cg13741927 chr9:139327495 INPP5E -0.24 -5.42 -0.44 2.93e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2204008 0.689 rs1581357 chr12:38391479 C/G cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.72e-11 Bladder cancer; TGCT cis rs12477438 0.765 rs4851183 chr2:99629149 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs7098414 0.511 rs7071752 chr10:82159539 C/A cg01528321 chr10:82214614 TSPAN14 0.56 4.98 0.41 2.09e-6 Post bronchodilator FEV1; TGCT cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg23283495 chr1:209979779 IRF6 0.65 5.53 0.44 1.81e-7 Cleft lip with or without cleft palate; TGCT cis rs72945132 0.556 rs57172967 chr11:70160060 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg10117171 chr1:25599238 RHD -0.3 -4.92 -0.4 2.69e-6 Erythrocyte sedimentation rate; TGCT cis rs12142240 0.698 rs57267378 chr1:46816644 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs12049351 0.774 rs754025 chr1:229637297 C/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs12497850 0.931 rs7643368 chr3:48992855 T/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.41 -0.44 3.09e-7 Parkinson's disease; TGCT cis rs13191362 0.935 rs35537826 chr6:163145867 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.93 7.06 0.54 1.05e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6912958 0.781 rs2300906 chr6:88207155 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs4654899 0.865 rs6700459 chr1:21279396 T/C cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6545883 0.931 rs7557230 chr2:61736652 A/T cg15711740 chr2:61764176 XPO1 -0.56 -5.11 -0.42 1.17e-6 Tuberculosis; TGCT cis rs514406 0.644 rs4926928 chr1:53210163 G/T cg01802117 chr1:53393560 SCP2 -0.41 -4.86 -0.4 3.48e-6 Monocyte count; TGCT cis rs7647973 0.922 rs57273516 chr3:49483074 A/G cg05785598 chr3:49045655 WDR6 0.37 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs6460942 0.841 rs62448597 chr7:12449110 G/C cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs4460629 0.742 rs7548955 chr1:155082298 T/C cg23973274 chr1:155060172 NA -0.26 -4.72 -0.39 6.25e-6 Serum magnesium levels; TGCT cis rs12200560 0.505 rs1988040 chr6:97076271 G/A cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs17253792 0.822 rs79921041 chr14:56090779 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3791556 0.741 rs3791542 chr2:240103955 A/G cg03281426 chr2:240109471 HDAC4 -0.27 -4.65 -0.39 8.44e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs669446 0.533 rs4660261 chr1:44229597 G/A cg12908607 chr1:44402522 ARTN -0.63 -7.47 -0.56 1.25e-11 Amyotrophic lateral sclerosis (age of onset); TGCT trans rs1005277 0.579 rs176838 chr10:38371899 A/T cg17830980 chr10:43048298 ZNF37B 0.86 9.99 0.67 1.31e-17 Extrinsic epigenetic age acceleration; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg11965913 chr1:205819406 PM20D1 0.54 7.73 0.57 3.21e-12 Menarche (age at onset); TGCT cis rs524281 0.692 rs10791845 chr11:65834340 C/G cg00563793 chr11:65837595 PACS1 -0.51 -4.52 -0.38 1.44e-5 Electroencephalogram traits; TGCT cis rs57920188 0.535 rs10915664 chr1:4093700 G/A cg20703997 chr1:4087676 NA 0.49 5.75 0.46 6.69e-8 Interleukin-17 levels; TGCT cis rs7412746 0.587 rs3849279 chr1:150944707 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.5 0.37 1.52e-5 Melanoma; TGCT cis rs34734847 1.000 rs2948149 chr12:121162854 T/G cg21892295 chr12:121157589 UNC119B -0.22 -5.39 -0.44 3.48e-7 Mean corpuscular volume; TGCT cis rs7255045 0.789 rs1078264 chr19:12963143 T/C cg06537894 chr19:12978706 MAST1 -0.49 -4.48 -0.37 1.69e-5 Mean corpuscular volume; TGCT cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg05368731 chr17:41323189 NBR1 1.07 12.31 0.74 3.02e-23 Menopause (age at onset); TGCT cis rs6674176 0.696 rs4448553 chr1:44411589 A/G cg12908607 chr1:44402522 ARTN -0.73 -9.26 -0.64 7.67e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs12478296 0.681 rs55802421 chr2:243033962 C/T cg06360820 chr2:242988706 NA -0.61 -4.75 -0.39 5.52e-6 Obesity-related traits; TGCT cis rs3020736 0.500 rs2413672 chr22:42513261 C/T cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12049351 0.774 rs2145395 chr1:229670981 T/C cg12130225 chr1:229698885 NA 0.38 4.63 0.38 8.95e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs13242816 1.000 rs1018859 chr7:116067347 C/T cg02799643 chr7:116139180 CAV2 -0.44 -5.08 -0.42 1.33e-6 P wave duration; TGCT trans rs10504390 0.656 rs78310018 chr8:66486522 T/C cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.26e-10 IgG glycosylation; TGCT cis rs12579753 0.879 rs11115007 chr12:82164673 A/T cg07988820 chr12:82153109 PPFIA2 -0.7 -7.9 -0.58 1.31e-12 Resting heart rate; TGCT cis rs7666738 0.710 rs7674407 chr4:98838522 A/G cg18180107 chr4:99064573 C4orf37 0.56 5.17 0.42 9.04e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs804292 0.763 rs8191514 chr8:11627113 C/G cg26752888 chr8:11627280 NEIL2 1.1 11.91 0.73 2.89e-22 Alcohol dependence;Nicotine use; TGCT cis rs7044106 0.762 rs1886337 chr9:123443776 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.47 0.5 2.01e-9 Hip circumference adjusted for BMI; TGCT cis rs9296092 0.521 rs9461886 chr6:33526770 T/C cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg06558623 chr16:89946397 TCF25 0.53 6.48 0.5 1.99e-9 Skin colour saturation; TGCT cis rs10501293 0.956 rs10837999 chr11:43068860 T/G cg03447554 chr11:43094025 NA 0.46 6.64 0.51 8.94e-10 Cognitive performance; TGCT trans rs9951602 0.512 rs12455566 chr18:76655926 A/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.71 0.75 3.32e-24 Obesity-related traits; TGCT cis rs6714710 0.627 rs6748124 chr2:98519014 T/C cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs514406 0.861 rs551435 chr1:53260537 G/T cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs910316 0.789 rs12894419 chr14:75471802 C/T cg11812906 chr14:75593930 NEK9 0.58 5.56 0.45 1.6e-7 Height; TGCT cis rs4149423 1.000 rs4149423 chr2:108916044 A/G cg06795125 chr2:108905320 SULT1C2 -0.45 -6.85 -0.52 3.06e-10 Lobe size; TGCT trans rs10501293 0.746 rs1565252 chr11:43009119 A/C cg23728189 chr2:10470961 HPCAL1 -0.27 -6.67 -0.51 7.41e-10 Cognitive performance; TGCT cis rs7681440 0.904 rs6532192 chr4:90764131 G/A cg20003494 chr4:90757398 SNCA -0.63 -6.09 -0.48 1.3e-8 Dementia with Lewy bodies; TGCT cis rs6598955 0.543 rs3795687 chr1:26560745 G/A cg24519413 chr1:26490540 NA -0.26 -4.73 -0.39 6.1e-6 Obesity-related traits; TGCT cis rs155076 1.000 rs658244 chr13:21850976 T/C cg11317459 chr13:21872234 NA -1.42 -12.26 -0.74 4.07e-23 White matter hyperintensity burden; TGCT cis rs71435601 0.600 rs312984 chr2:21378778 C/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs950027 0.620 rs1049518 chr15:45653367 G/A cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs7659604 0.676 rs6534323 chr4:122695888 G/A cg20573242 chr4:122745356 CCNA2 0.52 4.61 0.38 9.67e-6 Type 2 diabetes; TGCT cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg03806693 chr22:41940476 POLR3H 1.08 11.99 0.73 1.84e-22 Vitiligo; TGCT cis rs3806843 0.517 rs246031 chr5:140333107 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg01238044 chr22:24384105 GSTT1 -0.5 -4.61 -0.38 9.97e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6964587 0.626 rs10280301 chr7:91524258 A/T cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs5167 0.536 rs1882752 chr19:45461342 G/C cg09555818 chr19:45449301 APOC2 0.23 4.66 0.39 7.96e-6 Blood protein levels; TGCT cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg21724239 chr8:58056113 NA 0.45 4.94 0.41 2.44e-6 Developmental language disorder (linguistic errors); TGCT cis rs9549367 0.712 rs2316443 chr13:113864837 G/A cg18105134 chr13:113819100 PROZ -0.38 -6.47 -0.5 2.08e-9 Platelet distribution width; TGCT cis rs3849570 0.555 rs6548783 chr3:81993621 G/A cg07356753 chr3:81810745 GBE1 -0.61 -5.39 -0.44 3.47e-7 Waist circumference;Body mass index; TGCT cis rs6495367 1.000 rs13380109 chr15:79378775 G/A cg17916960 chr15:79447300 NA 0.35 4.94 0.41 2.48e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT trans rs2469997 0.925 rs2470004 chr8:120358445 C/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs12477438 0.520 rs11123761 chr2:99705903 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs9296092 0.538 rs62405941 chr6:33517297 G/A cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.25e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs3008870 1.000 rs2755248 chr1:67492624 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.4 0.72 5.07e-21 Lymphocyte percentage of white cells; TGCT cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg14262678 chr6:151773367 RMND1;C6orf211 0.54 5.28 0.43 5.5e-7 Menarche (age at onset); TGCT cis rs3784262 0.565 rs3809535 chr15:58359787 T/C cg12031962 chr15:58353849 ALDH1A2 -0.36 -5.13 -0.42 1.08e-6 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1215050 0.791 rs1025201 chr4:98902938 A/G cg05340658 chr4:99064831 C4orf37 -0.46 -5.82 -0.46 4.74e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7539409 0.915 rs6576945 chr1:84252882 A/G cg10977910 chr1:84465055 TTLL7 0.83 4.5 0.37 1.58e-5 Alzheimer's disease; TGCT cis rs2932538 0.922 rs6659677 chr1:113087076 G/C cg22162597 chr1:113214053 CAPZA1 0.27 5.89 0.47 3.46e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs10489202 0.608 rs7533646 chr1:168077593 A/C cg24449463 chr1:168025552 DCAF6 -0.49 -5.06 -0.41 1.49e-6 Schizophrenia; TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs7027203 1.000 rs7854820 chr9:96526027 A/G cg14396892 chr9:96623032 NA 0.24 4.66 0.39 8.02e-6 DNA methylation (variation); TGCT cis rs11785400 0.793 rs7017851 chr8:143722038 G/T cg24634471 chr8:143751801 JRK 0.53 5.11 0.42 1.17e-6 Schizophrenia; TGCT cis rs12549902 0.966 rs10504042 chr8:41515993 G/A cg00088007 chr8:41504566 NKX6-3 0.34 5.31 0.43 4.93e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs9611519 1.000 rs9611520 chr22:41613303 C/T cg13695892 chr22:41940480 POLR3H -0.5 -4.5 -0.37 1.56e-5 Neuroticism; TGCT cis rs11098499 0.754 rs2036856 chr4:120249288 G/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs8067545 0.750 rs9897246 chr17:19965702 T/G cg13482628 chr17:19912719 NA 0.54 4.64 0.38 8.78e-6 Schizophrenia; TGCT cis rs514406 0.683 rs6588440 chr1:53209587 C/T cg24675658 chr1:53192096 ZYG11B 0.83 10.09 0.67 7.59e-18 Monocyte count; TGCT cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg08219700 chr8:58056026 NA 0.31 4.53 0.38 1.36e-5 Developmental language disorder (linguistic errors); TGCT cis rs112217694 1.000 rs77015219 chr4:104655062 A/T cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs1215050 0.669 rs783962 chr4:98884473 G/A cg17366294 chr4:99064904 C4orf37 -0.58 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8177253 1.000 rs8177240 chr3:133477701 T/G cg20276088 chr3:133502917 NA -0.24 -5.02 -0.41 1.77e-6 Iron status biomarkers; TGCT cis rs6545883 0.894 rs6709441 chr2:61436930 A/T cg15711740 chr2:61764176 XPO1 0.54 4.47 0.37 1.73e-5 Tuberculosis; TGCT cis rs12477438 0.501 rs6708878 chr2:99801564 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs6840360 0.571 rs11940881 chr4:152501050 C/G cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg04944784 chr2:26401820 FAM59B -0.73 -6.04 -0.48 1.65e-8 Gut microbiome composition (summer); TGCT cis rs6582630 0.502 rs11504451 chr12:38425294 G/A cg13010199 chr12:38710504 ALG10B 0.56 4.44 0.37 2e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs4654899 0.802 rs3767247 chr1:21227338 T/C cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6424115 0.867 rs34902309 chr1:24192200 A/G cg15997130 chr1:24165203 NA -0.89 -10.26 -0.68 2.96e-18 Immature fraction of reticulocytes; TGCT cis rs2617583 0.509 rs62331137 chr5:1459573 A/G cg13982541 chr5:1466431 LPCAT1 0.19 4.51 0.38 1.48e-5 Breast cancer; TGCT cis rs7249142 0.512 rs12981160 chr19:19298099 T/A cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.57 5.62 0.45 1.21e-7 IgG glycosylation; TGCT cis rs9682041 1.000 rs9682041 chr3:170091902 C/T cg11886554 chr3:170076028 SKIL 0.83 6.37 0.5 3.41e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7523273 0.606 rs2724387 chr1:207932617 T/G cg22525895 chr1:207977042 MIR29B2 0.52 8.49 0.61 5.2e-14 Schizophrenia; TGCT cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg07424592 chr7:64974309 NA 1.33 8.82 0.62 8.94e-15 Diabetic kidney disease; TGCT cis rs11190604 1.000 rs2495745 chr10:102329075 A/G cg16342193 chr10:102329863 NA -0.42 -5.39 -0.44 3.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.49 -4.58 -0.38 1.09e-5 Prudent dietary pattern; TGCT cis rs7772486 0.790 rs4280983 chr6:146280790 G/C cg05347473 chr6:146136440 FBXO30 -0.54 -5.22 -0.42 7.44e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs8180040 0.966 rs13072802 chr3:47346415 G/C cg27129171 chr3:47204927 SETD2 0.7 8.88 0.62 6.43e-15 Colorectal cancer; TGCT cis rs9512730 0.553 rs6491212 chr13:28049631 T/C cg04070771 chr13:27998621 GTF3A 0.52 4.7 0.39 6.83e-6 Schizophrenia; TGCT cis rs10242455 0.702 rs116671616 chr7:98954558 C/T cg13560068 chr7:99070416 ZNF789 1.1 4.68 0.39 7.38e-6 Blood metabolite levels; TGCT cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.541 rs5026687 chr6:8473957 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.3e-6 Motion sickness; TGCT cis rs9928842 0.882 rs9927264 chr16:75260241 T/C cg09066997 chr16:75300724 BCAR1 0.28 5.04 0.41 1.63e-6 Alcoholic chronic pancreatitis; TGCT cis rs7666738 0.830 rs10470893 chr4:99038756 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7614311 0.636 rs73117045 chr3:63910613 A/G cg22134162 chr3:63841271 THOC7 -0.49 -6.17 -0.48 8.78e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs9517320 0.534 rs9556963 chr13:99157026 G/A cg07423050 chr13:99094983 FARP1 -0.29 -5.81 -0.46 5.02e-8 Longevity; TGCT cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg19635926 chr16:89946313 TCF25 0.29 4.84 0.4 3.84e-6 Skin colour saturation; TGCT cis rs8026198 0.929 rs1659212 chr15:42625952 C/T cg02624051 chr15:42371635 PLA2G4D -0.34 -4.46 -0.37 1.82e-5 Fibrinogen levels; TGCT cis rs2361718 0.933 rs8066452 chr17:78104080 A/G cg09238746 chr17:78121135 EIF4A3 -0.56 -4.84 -0.4 3.83e-6 Yeast infection; TGCT cis rs3796352 1.000 rs34943350 chr3:53012888 C/T cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4824093 0.610 rs4824113 chr22:50284974 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.5 5.14 0.42 1.05e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs28595532 0.920 rs114684527 chr4:119749252 G/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4072705 0.935 rs2184219 chr9:127532904 A/G cg13476313 chr9:127244764 NR5A1 0.3 4.67 0.39 7.59e-6 Menarche (age at onset); TGCT cis rs2458413 0.522 rs2514657 chr8:105331215 T/C cg04554929 chr8:105342491 NA -0.62 -9.39 -0.64 3.73e-16 Paget's disease; TGCT cis rs909674 0.818 rs5757680 chr22:39844793 C/T cg11247378 chr22:39784982 NA 0.69 8.25 0.6 1.96e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs75059851 0.756 rs73036086 chr11:133841782 C/T cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs593982 1.000 rs56257941 chr11:65505641 C/T cg08755490 chr11:65554678 OVOL1 -1.48 -10.77 -0.7 1.68e-19 Atopic dermatitis; TGCT cis rs1023500 0.505 rs134887 chr22:42674239 A/G cg05082376 chr22:42548792 NA -0.21 -4.47 -0.37 1.76e-5 Schizophrenia; TGCT cis rs2439831 0.681 rs7175434 chr15:43628542 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.9 6.73 0.52 5.55e-10 Lung cancer in ever smokers; TGCT cis rs931608 0.640 rs2957824 chr19:22579316 T/C cg23859931 chr19:22123797 NA 0.61 4.91 0.4 2.77e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg02353165 chr6:42928485 GNMT 0.94 10.95 0.7 6.33e-20 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10858047 0.883 rs41312702 chr1:115118622 A/G cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs875971 0.964 rs1643388 chr7:65844562 T/C cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs875971 1.000 rs1981798 chr7:65954903 G/T cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs3806843 0.576 rs246009 chr5:140338069 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.41 5.24 0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs9399135 0.935 rs6908681 chr6:135337733 A/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs72615157 0.561 rs113844570 chr7:99873778 A/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.65 -5.2 -0.42 8.01e-7 Lung function (FEV1/FVC); TGCT cis rs2204008 0.774 rs7305085 chr12:38263511 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs5167 0.533 rs55778858 chr19:45485465 G/A cg09555818 chr19:45449301 APOC2 0.23 4.62 0.38 9.53e-6 Blood protein levels; TGCT cis rs9486719 1.000 rs11152951 chr6:96894135 C/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.65 -5.2 -0.42 8.01e-7 Lung function (FEV1/FVC); TGCT cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg06221963 chr1:154839813 KCNN3 -0.78 -13.2 -0.76 2.22e-25 Prostate cancer; TGCT cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs7647973 1.000 rs3905330 chr3:49550774 A/G cg05785598 chr3:49045655 WDR6 0.37 4.59 0.38 1.05e-5 Menarche (age at onset); TGCT cis rs2334880 0.680 rs1364210 chr16:71603487 G/A cg06353428 chr16:71660113 MARVELD3 -1.3 -10.66 -0.69 3.08e-19 Malaria; TGCT cis rs2932538 0.922 rs34531155 chr1:113141550 C/T cg10983938 chr1:113465962 AFARP1;SLC16A1 0.21 4.44 0.37 1.99e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs116095464 0.558 rs73031482 chr5:227594 G/A cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.49 0.37 1.62e-5 Breast cancer; TGCT cis rs1865760 0.534 rs72834629 chr6:26023032 C/T cg16482183 chr6:26056742 HIST1H1C 0.67 5.44 0.44 2.72e-7 Height; TGCT cis rs797680 0.897 rs12133907 chr1:93850283 C/A cg17826107 chr1:92977322 EVI5 -0.24 -5.6 -0.45 1.29e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7666738 0.606 rs4637413 chr4:99088151 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Vitiligo; TGCT cis rs17764205 0.777 rs10424519 chr19:3253532 C/G cg20583073 chr19:3178759 S1PR4 -0.32 -4.63 -0.38 9.24e-6 Bipolar disorder and schizophrenia; TGCT cis rs9325144 0.647 rs11168819 chr12:39011082 C/A cg10518543 chr12:38710700 ALG10B -0.51 -4.94 -0.41 2.49e-6 Morning vs. evening chronotype; TGCT cis rs1153858 0.668 rs63603561 chr15:45593323 T/A cg26924012 chr15:45694286 SPATA5L1 -1.0 -10.83 -0.7 1.22e-19 Homoarginine levels; TGCT cis rs12142240 0.660 rs72890715 chr1:46852077 A/G cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs28595532 0.920 rs10025640 chr4:119787451 G/A cg21605333 chr4:119757512 SEC24D 1.44 8.24 0.6 2.03e-13 Cannabis dependence symptom count; TGCT cis rs2046867 0.862 rs6549483 chr3:72805316 T/G cg25664220 chr3:72788482 NA -0.55 -6.96 -0.53 1.79e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1865760 0.566 rs2051544 chr6:26071093 C/T cg17042849 chr6:26104293 HIST1H4C -0.63 -5.5 -0.44 2.1e-7 Height; TGCT cis rs8180040 0.966 rs9683177 chr3:47490493 G/A cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs1903068 0.853 rs10012589 chr4:56002689 A/T cg01777861 chr4:56023843 NA 0.53 6.21 0.49 7.2e-9 Endometriosis; TGCT cis rs9926296 0.557 rs11076618 chr16:89807705 T/C cg04287289 chr16:89883240 FANCA 0.67 6.7 0.52 6.53e-10 Vitiligo; TGCT cis rs6089584 0.566 rs6061972 chr20:60610245 C/T cg06108461 chr20:60628389 TAF4 -0.44 -5.58 -0.45 1.44e-7 Body mass index; TGCT cis rs617219 0.698 rs13177470 chr5:78495899 T/C cg09550809 chr5:78407562 BHMT 0.4 5.71 0.46 7.79e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1008375 0.900 rs12650220 chr4:17595365 A/T cg16339924 chr4:17578868 LAP3 0.8 6.56 0.51 1.34e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs826838 1.000 rs10875717 chr12:38911174 T/C cg13010199 chr12:38710504 ALG10B 0.78 6.42 0.5 2.61e-9 Heart rate; TGCT cis rs7666738 0.830 rs13133619 chr4:99067312 C/G cg18180107 chr4:99064573 C4orf37 -0.58 -5.32 -0.43 4.68e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.44 6.28 0.49 5.28e-9 Lymphocyte counts; TGCT cis rs7714584 1.000 rs59980321 chr5:150241813 A/T cg22134413 chr5:150180641 NA 0.93 6.99 0.53 1.52e-10 Crohn's disease; TGCT cis rs6840360 0.571 rs4696278 chr4:152558978 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs28451001 chr4:98924544 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs35146811 0.735 rs1636978 chr7:99813912 G/A cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs4727027 0.865 rs12154368 chr7:148862041 C/T cg23583168 chr7:148888333 NA -0.76 -10.09 -0.67 7.46e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1348850 0.651 rs1901824 chr2:178225466 T/C cg22681709 chr2:178499509 PDE11A -0.35 -4.54 -0.38 1.3e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs11098499 0.779 rs72918579 chr4:120333222 G/C cg09307838 chr4:120376055 NA 0.7 6.72 0.52 5.94e-10 Corneal astigmatism; TGCT cis rs17443541 0.507 rs2346107 chr2:200447353 G/A cg00055341 chr2:200446845 NA -0.38 -4.6 -0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs9549367 0.673 rs3024735 chr13:113819513 G/A cg00898013 chr13:113819073 PROZ -0.52 -6.43 -0.5 2.52e-9 Platelet distribution width; TGCT cis rs4478858 0.735 rs7547897 chr1:31797593 G/A cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs858239 0.600 rs1115941 chr7:23137188 C/T cg05602783 chr7:23145260 KLHL7 -0.66 -5.55 -0.45 1.65e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6831352 0.918 rs34805407 chr4:100050786 C/A cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs2033711 0.837 rs3764535 chr19:58929052 G/A cg13877915 chr19:58951672 ZNF132 0.88 10.81 0.7 1.36e-19 Uric acid clearance; TGCT cis rs13256369 0.802 rs11781257 chr8:8559663 A/T cg18904891 chr8:8559673 CLDN23 0.56 5.0 0.41 1.94e-6 Obesity-related traits; TGCT cis rs2688608 0.934 rs2675679 chr10:75658581 C/T cg19442545 chr10:75533431 FUT11 -0.3 -4.76 -0.39 5.23e-6 Inflammatory bowel disease; TGCT cis rs1215050 0.791 rs165247 chr4:98692399 A/G cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10883723 0.810 rs2296582 chr10:104244139 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 8.53 0.61 4.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2760061 0.659 rs708107 chr1:228189495 C/T cg18477163 chr1:228402036 OBSCN 0.34 6.92 0.53 2.17e-10 Diastolic blood pressure; TGCT cis rs1538970 0.884 rs1771551 chr1:45883643 C/G cg05343316 chr1:45956843 TESK2 0.74 5.81 0.46 4.85e-8 Platelet count; TGCT cis rs6089829 0.962 rs1116450 chr20:61658210 T/C cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg00080972 chr5:178986291 RUFY1 0.54 6.6 0.51 1.07e-9 Lung cancer; TGCT cis rs6121246 0.567 rs6060247 chr20:30190720 C/G cg18721089 chr20:30220636 NA -0.63 -6.86 -0.52 2.95e-10 Mean corpuscular hemoglobin; TGCT cis rs8017423 0.522 rs12887028 chr14:90819605 A/G cg04374321 chr14:90722782 PSMC1 -0.56 -5.62 -0.45 1.19e-7 Mortality in heart failure; TGCT trans rs2970818 0.831 rs2909381 chr12:4606527 T/C cg22985033 chr20:36975012 LBP 0.27 6.71 0.52 6.11e-10 Phosphorus levels; TGCT trans rs1005277 0.577 rs4934906 chr10:38015028 C/T cg17830980 chr10:43048298 ZNF37B -0.63 -6.84 -0.52 3.16e-10 Extrinsic epigenetic age acceleration; TGCT cis rs7267979 1.000 rs2482930 chr20:25334115 G/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10507380 0.824 rs79079188 chr13:27926284 A/G cg25543773 chr13:27185723 WASF3 0.32 4.52 0.38 1.45e-5 Electrocardiographic traits; TGCT cis rs17764205 0.568 rs72987040 chr19:3251116 C/A cg18738857 chr19:3606974 TBXA2R -0.73 -4.53 -0.38 1.35e-5 Bipolar disorder and schizophrenia; TGCT cis rs7769051 0.808 rs1467403 chr6:133089952 T/A cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs11696845 0.666 rs13042905 chr20:43379454 T/C cg25301532 chr20:43378953 KCNK15 0.45 5.03 0.41 1.69e-6 Obesity-related traits; TGCT cis rs2233152 0.519 rs11083567 chr19:41318306 C/T cg23743927 chr19:41304969 EGLN2 -0.57 -4.45 -0.37 1.89e-5 Kawasaki disease; TGCT cis rs7246657 0.722 rs2927747 chr19:38159530 C/T cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs7681440 0.845 rs6843084 chr4:90766230 T/C cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs2840044 0.517 rs2124247 chr17:33885468 G/A cg05299278 chr17:33885742 SLFN14 0.22 4.92 0.4 2.7e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs6815814 0.851 rs5743551 chr4:38807654 T/C cg02016764 chr4:38805732 TLR1 -0.3 -5.24 -0.43 6.74e-7 Breast cancer; TGCT cis rs1729951 0.546 rs12054408 chr3:136677645 T/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs2439831 0.850 rs28509275 chr15:44098105 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.96 6.13 0.48 1.1e-8 Lung cancer in ever smokers; TGCT cis rs6570726 0.935 rs382910 chr6:145865941 G/A cg05347473 chr6:146136440 FBXO30 0.49 4.51 0.38 1.46e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs17102423 0.826 rs17825846 chr14:65598752 C/G cg11161011 chr14:65562177 MAX -0.57 -7.95 -0.58 1.01e-12 Obesity-related traits; TGCT cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg04546413 chr19:29218101 NA 0.84 6.76 0.52 4.71e-10 Methadone dose in opioid dependence; TGCT cis rs78487399 0.808 rs13414140 chr2:43671176 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.66 -0.45 9.88e-8 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7822232 0.908 rs1127096 chr8:145140472 A/G cg06239191 chr8:145163136 KIAA1875 -0.88 -6.45 -0.5 2.26e-9 Blood metabolite levels; TGCT cis rs709400 0.659 rs3825566 chr14:103852725 C/T cg12935359 chr14:103987150 CKB 0.35 5.28 0.43 5.62e-7 Body mass index; TGCT cis rs2455799 0.573 rs2255248 chr3:15754849 A/G cg16303742 chr3:15540471 COLQ 0.24 4.71 0.39 6.64e-6 Mean platelet volume; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg01171360 chr6:293285 DUSP22 -0.78 -7.87 -0.58 1.47e-12 Menopause (age at onset); TGCT trans rs7824557 0.569 rs10106207 chr8:11015338 C/T cg15556689 chr8:8085844 FLJ10661 -0.86 -8.59 -0.61 3.03e-14 Retinal vascular caliber; TGCT cis rs7258465 1.000 rs7251653 chr19:18608283 C/T cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs7017914 0.811 rs1389204 chr8:71928298 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs12497850 0.863 rs4858799 chr3:48728204 G/A cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Parkinson's disease; TGCT cis rs734999 0.505 rs4278312 chr1:2539555 A/G cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg02725872 chr8:58115012 NA -0.42 -5.11 -0.42 1.2e-6 Developmental language disorder (linguistic errors); TGCT trans rs7726839 0.540 rs12517638 chr5:645484 C/T cg11887960 chr12:57824829 NA 1.12 9.19 0.64 1.16e-15 Obesity-related traits; TGCT cis rs9549367 0.713 rs56002882 chr13:113830694 T/C cg18105134 chr13:113819100 PROZ -0.47 -8.24 -0.59 2.05e-13 Platelet distribution width; TGCT cis rs7659604 0.540 rs4240264 chr4:122683818 A/G cg19748678 chr4:122722346 EXOSC9 -0.51 -5.06 -0.41 1.46e-6 Type 2 diabetes; TGCT cis rs6089829 0.962 rs6062780 chr20:61666648 T/C cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7178572 1.000 rs34591043 chr15:77713586 A/G cg22256960 chr15:77711686 NA -0.95 -10.93 -0.7 6.95e-20 Type 2 diabetes; TGCT cis rs9393692 0.905 rs7450556 chr6:26299900 C/T cg13736514 chr6:26305472 NA -0.41 -5.77 -0.46 6.03e-8 Educational attainment; TGCT cis rs7267979 0.714 rs6132825 chr20:25238309 A/T cg16686733 chr20:25566563 NINL 0.49 4.46 0.37 1.8e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.534 rs34541797 chr6:146205304 A/G cg23711669 chr6:146136114 FBXO30 0.74 6.96 0.53 1.75e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3888647 0.561 rs4758617 chr11:2995185 T/A cg05729581 chr11:3078854 CARS -0.54 -4.82 -0.4 4.19e-6 Type 2 diabetes; TGCT cis rs4975709 0.610 rs4975705 chr5:1860359 T/C cg15595755 chr5:1867978 NA 0.46 5.31 0.43 4.79e-7 Cardiovascular disease risk factors; TGCT cis rs1371867 0.846 rs1660347 chr8:101314980 G/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs7726839 0.561 rs72703046 chr5:580129 T/C cg09021430 chr5:549028 NA -0.37 -5.39 -0.44 3.37e-7 Obesity-related traits; TGCT cis rs8180040 0.587 rs1466741 chr3:47247214 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.35 -0.6 1.13e-13 Colorectal cancer; TGCT cis rs546131 0.614 rs473885 chr11:34851961 G/A cg06937548 chr11:34938143 PDHX;APIP 0.52 4.55 0.38 1.28e-5 Lung disease severity in cystic fibrosis; TGCT cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg03452623 chr4:187889614 NA -0.36 -5.3 -0.43 5.01e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs3820068 0.603 rs35509554 chr1:15993514 C/T cg05660106 chr1:15850417 CASP9 0.7 6.58 0.51 1.21e-9 Systolic blood pressure; TGCT cis rs10465746 0.905 rs12127266 chr1:84360767 T/G cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs35160687 0.871 rs11127028 chr2:86537509 A/T cg12542933 chr2:85804724 VAMP8 0.41 4.9 0.4 2.97e-6 Night sleep phenotypes; TGCT cis rs7829975 0.871 rs7829826 chr8:8578120 T/A cg15556689 chr8:8085844 FLJ10661 -0.7 -6.06 -0.48 1.53e-8 Mood instability; TGCT trans rs1814175 0.817 rs1615305 chr11:49895222 T/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.86e-13 Height; TGCT cis rs17001868 0.892 rs73167027 chr22:40808676 A/T cg07138101 chr22:40742427 ADSL 0.78 5.29 0.43 5.4e-7 Mammographic density (dense area); TGCT cis rs6430585 0.640 rs3816155 chr2:136552526 A/C cg07169764 chr2:136633963 MCM6 -1.19 -11.11 -0.71 2.49e-20 Corneal structure; TGCT cis rs7914558 1.000 rs7914558 chr10:104775908 G/A cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.34e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs599083 0.744 rs603129 chr11:68186669 A/T cg16797656 chr11:68205561 LRP5 -0.26 -4.44 -0.37 2.01e-5 Bone mineral density (spine); TGCT cis rs2580764 0.515 rs7570629 chr2:55255935 A/T cg09592903 chr2:55203963 RTN4 -0.27 -6.07 -0.48 1.46e-8 Mean platelet volume; TGCT cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg06634786 chr22:41940651 POLR3H -0.9 -8.58 -0.61 3.3e-14 Vitiligo; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg12419862 chr22:24373484 LOC391322 -0.79 -8.23 -0.59 2.19e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg15691649 chr6:25882328 NA -0.41 -4.73 -0.39 5.91e-6 Intelligence (multi-trait analysis); TGCT cis rs7615952 0.673 rs3811677 chr3:125648080 G/A cg05084668 chr3:125655381 ALG1L -0.76 -6.08 -0.48 1.39e-8 Blood pressure (smoking interaction); TGCT cis rs7954584 0.567 rs10840632 chr12:122375460 C/T cg22168489 chr12:122356033 WDR66 0.22 4.68 0.39 7.36e-6 Mean corpuscular volume; TGCT cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.1 9.08 0.63 2.06e-15 Platelet count; TGCT cis rs7818688 0.697 rs35032356 chr8:95977484 G/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7210837 0.527 rs35638255 chr17:16784344 G/C cg00849854 chr17:17780937 TOM1L2 0.35 4.45 0.37 1.85e-5 Response to platinum-based chemotherapy (cisplatin); TGCT cis rs11785400 1.000 rs754957 chr8:143746416 A/G cg24634471 chr8:143751801 JRK 0.55 5.92 0.47 2.93e-8 Schizophrenia; TGCT cis rs12682352 0.650 rs13265731 chr8:8673320 T/C cg06636001 chr8:8085503 FLJ10661 0.6 5.07 0.41 1.41e-6 Neuroticism; TGCT cis rs9830388 1.000 rs60430884 chr3:23559661 G/T cg26146027 chr3:24536889 THRB 0.5 4.44 0.37 1.96e-5 RR interval (tricyclic/tetracyclic antidepressant use interaction); TGCT cis rs4455778 0.561 rs56235551 chr7:49128132 C/T cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs6121246 0.567 rs6060249 chr20:30190944 G/A cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs61931739 0.500 rs6488215 chr12:34434803 A/T cg06521331 chr12:34319734 NA -0.28 -4.51 -0.38 1.47e-5 Morning vs. evening chronotype; TGCT cis rs910316 0.737 rs175065 chr14:75494983 T/C cg08847533 chr14:75593920 NEK9 -0.83 -8.74 -0.62 1.4e-14 Height; TGCT cis rs10751667 0.666 rs11246357 chr11:963980 A/C cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg13866156 chr1:1669148 SLC35E2 -0.22 -5.21 -0.42 7.51e-7 Body mass index; TGCT cis rs9796 0.689 rs11855797 chr15:41434679 C/T cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.84 -0.52 3.24e-10 Menopause (age at onset); TGCT cis rs597539 0.654 rs655816 chr11:68626405 A/G cg06112835 chr11:68658793 MRPL21 0.48 8.13 0.59 3.78e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg06618935 chr21:46677482 NA -0.37 -5.64 -0.45 1.1e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs344364 0.511 rs1742472 chr16:1953040 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.46 -5.31 -0.43 4.97e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg06634786 chr22:41940651 POLR3H -0.89 -8.16 -0.59 3.16e-13 Vitiligo; TGCT cis rs7044106 0.791 rs2416797 chr9:123480600 C/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 7.1 0.54 8.41e-11 Hip circumference adjusted for BMI; TGCT cis rs7208859 0.524 rs11653605 chr17:29088385 T/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2295359 1.000 rs9729046 chr1:67607082 C/G cg12940439 chr1:67600707 NA 0.59 6.16 0.48 9.5e-9 Psoriasis; TGCT cis rs9581857 0.547 rs7989917 chr13:28071271 G/A cg22138327 chr13:27999177 GTF3A 0.77 5.02 0.41 1.78e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs3617 0.539 rs4687687 chr3:52948332 A/G cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.85 0.4 3.57e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg00024416 chr22:24240387 NA 0.33 5.56 0.45 1.55e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg16145915 chr7:1198662 ZFAND2A -0.61 -8.66 -0.61 2.16e-14 Longevity;Endometriosis; TGCT cis rs4409675 0.576 rs6662916 chr1:28219873 G/T cg23691781 chr1:28212827 C1orf38 0.26 5.32 0.43 4.68e-7 Corneal astigmatism; TGCT cis rs8177253 1.000 rs8177262 chr3:133480652 A/G cg08048268 chr3:133502702 NA 0.6 8.64 0.61 2.33e-14 Iron status biomarkers; TGCT cis rs4383453 0.539 rs4678021 chr3:123102376 A/G cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs637571 0.780 rs677029 chr11:65683531 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.58 5.66 0.45 1.01e-7 Eosinophil percentage of white cells; TGCT cis rs2710642 0.888 rs13418889 chr2:63079775 T/C cg17519650 chr2:63277830 OTX1 0.66 6.14 0.48 1.02e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs7666738 0.830 rs11097600 chr4:98959564 T/G cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.8e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1355223 0.583 rs1396881 chr11:34870506 G/T cg24088639 chr11:34937564 PDHX;APIP -0.51 -4.54 -0.38 1.31e-5 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs1878931 0.582 rs40633 chr16:3425325 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.41 -0.5 2.7e-9 Body mass index (adult); TGCT cis rs2836974 0.965 rs34578707 chr21:40675167 G/A cg11644478 chr21:40555479 PSMG1 0.97 10.04 0.67 9.92e-18 Cognitive function; TGCT cis rs853679 0.567 rs3799499 chr6:28354250 G/T cg18815343 chr6:28367644 ZSCAN12 -0.52 -4.74 -0.39 5.68e-6 Depression; TGCT cis rs1577917 0.538 rs6454483 chr6:86418283 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.55 5.0 0.41 1.88e-6 Response to antipsychotic treatment; TGCT cis rs12887734 0.546 rs12886637 chr14:104222892 A/G cg26031613 chr14:104095156 KLC1 0.72 6.2 0.49 7.61e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7760949 0.888 rs9296853 chr6:13893945 T/A cg27413430 chr6:13925136 RNF182 0.52 4.74 0.39 5.64e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs7909074 1.000 rs10736831 chr10:45402311 G/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.33 -0.43 4.54e-7 Mean corpuscular volume; TGCT cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.74 0.46 6.79e-8 Menarche (age at onset); TGCT cis rs801193 0.967 rs2707853 chr7:66214010 G/A cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.84e-7 Aortic root size; TGCT cis rs6693567 0.516 rs3850844 chr1:150413940 G/T cg09579323 chr1:150459698 TARS2 0.52 4.62 0.38 9.56e-6 Migraine; TGCT cis rs7824557 0.614 rs2293860 chr8:11219386 G/T cg21775007 chr8:11205619 TDH 0.67 6.47 0.5 2.03e-9 Retinal vascular caliber; TGCT cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg09904177 chr6:26538194 HMGN4 0.68 6.31 0.49 4.52e-9 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.517 rs160017 chr10:30772894 A/G cg18806716 chr10:30721971 MAP3K8 -0.5 -5.74 -0.46 6.88e-8 Inflammatory bowel disease; TGCT cis rs4699052 0.625 rs11734836 chr4:104253203 G/A cg16532752 chr4:104119610 CENPE -0.5 -4.92 -0.4 2.71e-6 Testicular germ cell tumor; TGCT cis rs9807989 0.507 rs10200952 chr2:103027651 A/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs17376456 0.877 rs34595581 chr5:93369422 G/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg00786635 chr1:25594202 NA 0.54 5.78 0.46 5.67e-8 Erythrocyte sedimentation rate; TGCT cis rs5769707 0.935 rs739239 chr22:50050468 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.62 0.38 9.53e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg04234412 chr22:24373322 LOC391322 0.92 8.61 0.61 2.85e-14 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs453301 0.686 rs7814328 chr8:8876229 T/C cg00184457 chr8:8946301 NA -0.27 -4.93 -0.4 2.62e-6 Joint mobility (Beighton score); TGCT cis rs6993813 0.653 rs4355805 chr8:120016374 A/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs12142240 0.698 rs41293273 chr1:46806393 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.95 0.47 2.58e-8 Menopause (age at onset); TGCT cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg06634786 chr22:41940651 POLR3H 0.89 8.31 0.6 1.44e-13 Vitiligo; TGCT cis rs7192750 0.535 rs152826 chr16:72126180 A/G cg06353428 chr16:71660113 MARVELD3 1.12 5.56 0.45 1.59e-7 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs6840360 0.967 rs10028410 chr4:152606573 T/C cg17479576 chr4:152424074 FAM160A1 -0.48 -5.17 -0.42 9.02e-7 Intelligence (multi-trait analysis); TGCT cis rs67460515 0.563 rs6441362 chr3:160877613 G/A cg03342759 chr3:160939853 NMD3 -0.45 -4.53 -0.38 1.38e-5 Parkinson's disease; TGCT cis rs13188771 0.651 rs68082730 chr5:100903250 C/T cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs2241685 0.850 rs3748989 chr2:1946968 C/T cg21862353 chr2:1801628 MYT1L -0.52 -4.77 -0.39 5.05e-6 Attention deficit hyperactivity disorder; TGCT cis rs3125734 0.633 rs1368157 chr10:64001114 T/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.44 -0.37 1.96e-5 Rheumatoid arthritis; TGCT cis rs2204008 0.744 rs11514071 chr12:38392076 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.72e-11 Bladder cancer; TGCT cis rs6912958 0.525 rs59322 chr6:88020521 C/A cg04972856 chr6:88032051 C6orf162;GJB7 0.4 4.6 0.38 1.04e-5 Monocyte percentage of white cells; TGCT cis rs9341808 0.754 rs3805907 chr6:80973665 A/G cg08355045 chr6:80787529 NA -0.29 -5.0 -0.41 1.94e-6 Sitting height ratio; TGCT cis rs9309473 0.607 rs7586361 chr2:73601606 G/A cg20560298 chr2:73613845 ALMS1 -0.41 -4.54 -0.38 1.31e-5 Metabolite levels; TGCT trans rs208520 1.000 rs72882079 chr6:66973878 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.86 7.83 0.58 1.85e-12 Exhaled nitric oxide output; TGCT cis rs1865760 0.532 rs2794719 chr6:26088890 T/G cg16482183 chr6:26056742 HIST1H1C 0.57 4.82 0.4 4.06e-6 Height; TGCT cis rs9527 0.615 rs7917295 chr10:104701187 A/G cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs17152411 0.895 rs7094116 chr10:126587644 T/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs11874712 1.000 rs11082510 chr18:43656620 T/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs2637266 1.000 rs1077916 chr10:78381951 G/A cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs6598955 0.671 rs17163749 chr1:26568165 A/G cg04990556 chr1:26633338 UBXN11 0.62 4.82 0.4 4.06e-6 Obesity-related traits; TGCT cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs931608 0.585 rs55851405 chr19:22541686 T/C cg15554505 chr19:22123728 NA -0.65 -4.68 -0.39 7.41e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs10464366 0.746 rs4723821 chr7:39141532 A/G cg18850127 chr7:39170497 POU6F2 0.27 5.7 0.46 8.11e-8 IgG glycosylation; TGCT trans rs877282 0.898 rs11253356 chr10:768604 G/A cg22713356 chr15:30763199 NA 1.04 8.6 0.61 2.95e-14 Uric acid levels; TGCT cis rs12549902 0.897 rs12549294 chr8:41506380 A/G cg00088007 chr8:41504566 NKX6-3 0.34 5.47 0.44 2.33e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs60733400 0.782 rs4648564 chr1:2562169 C/T cg18854424 chr1:2615690 NA -0.47 -5.38 -0.44 3.57e-7 Multiple sclerosis; TGCT cis rs7772486 0.790 rs2249386 chr6:146186611 G/A cg23711669 chr6:146136114 FBXO30 0.97 11.36 0.71 6.35e-21 Lobe attachment (rater-scored or self-reported); TGCT cis rs7760949 0.889 rs9475795 chr6:13931270 A/C cg27413430 chr6:13925136 RNF182 0.73 6.76 0.52 4.76e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7666738 0.830 rs4492007 chr4:98959848 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2070488 0.804 rs4678605 chr3:38444489 T/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.79 7.75 0.57 2.92e-12 Electrocardiographic conduction measures; TGCT cis rs597539 0.652 rs496616 chr11:68672800 G/C cg06112835 chr11:68658793 MRPL21 0.47 8.28 0.6 1.65e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg02953382 chr22:24373134 LOC391322 -0.83 -9.54 -0.65 1.69e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7043114 0.525 rs8067 chr9:95218829 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.37 -0.43 3.72e-7 Height; TGCT cis rs801193 1.000 rs4717310 chr7:66161007 C/T cg18876405 chr7:65276391 NA 0.33 5.05 0.41 1.55e-6 Aortic root size; TGCT cis rs61680841 0.627 rs16945457 chr15:91795758 A/C cg13615036 chr15:91475826 UNC45A;HDDC3 -0.71 -4.82 -0.4 4.1e-6 Age-related hearing impairment; TGCT cis rs9581857 0.547 rs9581878 chr13:28104552 T/A cg22138327 chr13:27999177 GTF3A 0.72 4.75 0.39 5.45e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs881375 0.967 rs2270231 chr9:123650982 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.53 0.38 1.35e-5 Rheumatoid arthritis; TGCT cis rs2242116 0.793 rs9855938 chr3:46957298 G/A cg23352942 chr3:46931381 PTH1R -0.33 -4.92 -0.4 2.67e-6 Birth weight; TGCT cis rs826838 0.684 rs12367400 chr12:38618673 G/T cg13010199 chr12:38710504 ALG10B 0.65 5.15 0.42 9.92e-7 Heart rate; TGCT cis rs6754311 0.773 rs2322818 chr2:136775898 T/C cg07169764 chr2:136633963 MCM6 0.64 5.97 0.47 2.28e-8 Mosquito bite size; TGCT cis rs9443189 0.530 rs614065 chr6:76315633 G/A cg01950844 chr6:76311363 SENP6 0.99 6.27 0.49 5.49e-9 Prostate cancer; TGCT cis rs6089584 0.527 rs927589 chr20:60606363 A/G cg13770153 chr20:60521292 NA -0.39 -4.77 -0.39 5.17e-6 Body mass index; TGCT cis rs6665290 0.901 rs68087483 chr1:227202668 T/C cg10327440 chr1:227177885 CDC42BPA -0.98 -20.12 -0.87 7.08e-41 Myeloid white cell count; TGCT cis rs2836974 0.831 rs2836921 chr21:40516070 C/T cg11890956 chr21:40555474 PSMG1 1.03 10.49 0.69 7.98e-19 Cognitive function; TGCT cis rs9926296 0.656 rs2376884 chr16:89826922 C/T cg26513180 chr16:89883248 FANCA 0.7 6.76 0.52 4.76e-10 Vitiligo; TGCT trans rs1005277 0.579 rs1740735 chr10:38497777 A/C cg27523141 chr10:43048294 ZNF37B 0.68 7.92 0.58 1.12e-12 Extrinsic epigenetic age acceleration; TGCT cis rs42648 0.564 rs10224488 chr7:89810261 A/G cg25739043 chr7:89950458 NA -0.49 -4.51 -0.38 1.48e-5 Homocysteine levels; TGCT cis rs3784262 0.669 rs3742960 chr15:58248088 C/T cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.23 -0.49 6.77e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4285028 0.898 rs4305455 chr3:121619774 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.73 -6.28 -0.49 5.25e-9 Multiple sclerosis; TGCT cis rs9443645 0.869 rs9448591 chr6:79606490 C/T cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs57994353 0.828 rs11146021 chr9:139327858 A/G cg13741927 chr9:139327495 INPP5E 0.26 6.27 0.49 5.41e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs35306767 0.714 rs10508206 chr10:1075777 A/C cg26597838 chr10:835615 NA 0.53 6.08 0.48 1.35e-8 Eosinophil percentage of granulocytes; TGCT cis rs7208859 0.623 rs56378576 chr17:29010120 C/T cg14008862 chr17:28927542 LRRC37B2 0.84 5.1 0.42 1.22e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9457247 1.000 rs2769352 chr6:167378619 A/G cg23791538 chr6:167370224 RNASET2 0.53 5.19 0.42 8.41e-7 Crohn's disease; TGCT cis rs2228479 0.850 rs117285117 chr16:89910250 T/G cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs9993613 0.935 rs10019152 chr4:73518770 A/C cg15102770 chr4:73434591 ADAMTS3 -0.49 -4.52 -0.38 1.41e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg02353165 chr6:42928485 GNMT 0.97 9.68 0.66 7.73e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs875971 0.862 rs11765791 chr7:65936574 A/G cg11764359 chr7:65958608 NA 0.55 5.07 0.41 1.42e-6 Aortic root size; TGCT cis rs317689 0.613 rs315112 chr12:69785926 T/A cg19645103 chr12:69753606 YEATS4 -0.57 -4.8 -0.4 4.51e-6 Response to diuretic therapy; TGCT cis rs2657888 0.598 rs2657909 chr12:56895503 T/C cg23002907 chr12:56915593 RBMS2 0.41 5.35 0.43 4.14e-7 Adiponectin levels; TGCT cis rs1629083 1.000 rs1629083 chr11:118126576 C/T cg16594165 chr11:118135105 MPZL2 -0.34 -4.67 -0.39 7.79e-6 Lung cancer; TGCT cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg13683864 chr3:40499215 RPL14 -1.12 -11.97 -0.73 2.07e-22 Renal cell carcinoma; TGCT cis rs2303745 0.589 rs6512179 chr19:17399105 T/C cg04248312 chr19:17393744 ANKLE1 -0.34 -5.57 -0.45 1.54e-7 Systemic lupus erythematosus; TGCT cis rs10782582 0.609 rs112205173 chr1:76310100 C/T cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT trans rs561341 1.000 rs497479 chr17:30328605 C/T cg20587970 chr11:113659929 NA -1.03 -12.59 -0.75 6.52e-24 Hip circumference adjusted for BMI; TGCT cis rs9653442 1.000 rs11676922 chr2:100806940 T/A cg22139774 chr2:100720529 AFF3 -0.43 -7.69 -0.57 3.95e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10883723 0.847 rs3808934 chr10:104264280 C/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs11118844 0.793 rs17010720 chr1:221946403 A/G cg04222084 chr1:221915650 DUSP10 -0.7 -4.96 -0.41 2.25e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs4906332 1.000 rs3783398 chr14:103949378 C/T cg26031613 chr14:104095156 KLC1 0.56 4.56 0.38 1.21e-5 Coronary artery disease; TGCT cis rs765787 0.530 rs2668751 chr15:45517293 T/C cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs3617 0.599 rs12487379 chr3:52895785 G/A cg10802521 chr3:52805072 NEK4 -0.56 -6.46 -0.5 2.14e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9952991 0.941 rs8096138 chr18:12808140 C/G cg23544223 chr18:12777786 NA -0.6 -5.33 -0.43 4.56e-7 Inflammatory skin disease; TGCT cis rs2067615 0.524 rs9971765 chr12:107092299 G/A cg15890332 chr12:107067104 RFX4 0.29 5.75 0.46 6.61e-8 Heart rate; TGCT cis rs6750047 0.585 rs4670808 chr2:38267794 A/G cg07380506 chr2:38303506 CYP1B1 0.56 5.25 0.43 6.42e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs9534288 0.797 rs9534279 chr13:46584999 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs7095607 0.813 rs4745947 chr10:69931840 A/C cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.72e-6 Lung function (FVC); TGCT trans rs629535 0.814 rs62513378 chr8:70095788 G/C cg21567404 chr3:27674614 NA -0.57 -9.03 -0.63 2.83e-15 Dupuytren's disease; TGCT cis rs28595532 0.688 rs116053430 chr4:119731375 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs9513593 1.000 rs1964898 chr13:99997181 A/G cg21788972 chr13:99853209 UBAC2 0.56 4.47 0.37 1.76e-5 Psoriasis; TGCT cis rs992157 0.798 rs4674284 chr2:219161241 C/T cg00012203 chr2:219082015 ARPC2 -0.82 -8.11 -0.59 4.07e-13 Colorectal cancer; TGCT cis rs514406 0.584 rs12095247 chr1:53193796 A/C cg22166914 chr1:53195759 ZYG11B -0.5 -9.39 -0.64 3.79e-16 Monocyte count; TGCT cis rs7267979 0.966 rs2261794 chr20:25263062 T/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10744422 0.764 rs3844369 chr12:123293559 T/C cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs9527 0.590 rs10509766 chr10:104926334 T/C cg15744005 chr10:104629667 AS3MT -0.4 -4.59 -0.38 1.08e-5 Arsenic metabolism; TGCT cis rs7017914 0.905 rs2732115 chr8:71928854 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs9640161 0.711 rs60268791 chr7:150023800 G/T cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 9.08e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs2243480 1.000 rs13235972 chr7:65883605 C/T cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg11905131 chr22:24372483 LOC391322 -0.88 -10.14 -0.67 5.74e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs208520 0.507 rs9453585 chr6:66796668 C/T cg07460842 chr6:66804631 NA -1.08 -15.99 -0.82 6.47e-32 Exhaled nitric oxide output; TGCT cis rs79349575 0.783 rs28409394 chr17:46998118 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg16145915 chr7:1198662 ZFAND2A -0.46 -5.65 -0.45 1.03e-7 Longevity;Endometriosis; TGCT cis rs6952808 0.609 rs12699449 chr7:1951227 G/C cg22963979 chr7:1858916 MAD1L1 -0.38 -5.8 -0.46 5.26e-8 Bipolar disorder and schizophrenia; TGCT cis rs7584330 0.868 rs6760842 chr2:238398165 C/T cg16989719 chr2:238392110 NA 0.26 4.55 0.38 1.24e-5 Prostate cancer; TGCT cis rs7542091 0.748 rs2357231 chr1:210028454 A/C cg05527609 chr1:210001259 C1orf107 0.53 4.97 0.41 2.13e-6 Monobrow; TGCT cis rs6725041 0.547 rs1505353 chr2:213203057 C/A cg16329650 chr2:213403929 ERBB4 -0.67 -5.72 -0.46 7.68e-8 QT interval (ambient particulate matter interaction); TGCT cis rs1371867 0.846 rs1788182 chr8:101334620 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.08 0.42 1.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2013441 0.965 rs8068720 chr17:20214171 G/T cg23224458 chr17:20280056 CCDC144C -0.4 -4.75 -0.39 5.53e-6 Obesity-related traits; TGCT cis rs7666738 0.716 rs13136721 chr4:99085602 G/A cg18180107 chr4:99064573 C4orf37 0.55 4.91 0.4 2.8e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10465746 0.746 rs6699501 chr1:84389993 A/G cg10977910 chr1:84465055 TTLL7 0.71 7.15 0.54 6.64e-11 Obesity-related traits; TGCT cis rs7666738 0.830 rs1025204 chr4:99023441 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.01 0.41 1.82e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg10896456 chr17:42255109 ASB16;C17orf65 0.25 4.47 0.37 1.75e-5 Total body bone mineral density; TGCT cis rs514406 0.560 rs1889033 chr1:53211887 A/G cg22166914 chr1:53195759 ZYG11B -0.5 -9.19 -0.64 1.16e-15 Monocyte count; TGCT cis rs858239 0.539 rs4559148 chr7:23185967 G/A cg05602783 chr7:23145260 KLHL7 -0.68 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs116095464 0.558 rs6881920 chr5:222411 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs9640161 0.742 rs11767726 chr7:150018096 A/C cg10018233 chr7:150070692 REPIN1 -0.32 -4.7 -0.39 6.93e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs711245 0.637 rs6729495 chr2:36834192 T/A cg01206211 chr2:36825736 FEZ2 0.33 5.47 0.44 2.37e-7 Height; TGCT cis rs589249 0.889 rs4653212 chr1:37175329 G/C cg04012535 chr1:37176647 NA 0.33 5.39 0.44 3.46e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs12477438 0.520 rs10865029 chr2:99718298 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs6840360 0.582 rs2709826 chr4:152332120 G/T cg17479576 chr4:152424074 FAM160A1 -0.57 -5.98 -0.47 2.18e-8 Intelligence (multi-trait analysis); TGCT cis rs17433780 1.000 rs17433780 chr1:89474818 C/T cg09516651 chr1:89888402 LOC400759 -0.28 -5.04 -0.41 1.62e-6 Carotid intima media thickness; TGCT cis rs727505 1.000 rs10230610 chr7:124425398 A/C cg23710748 chr7:124431027 NA -0.27 -4.78 -0.39 4.82e-6 Lewy body disease; TGCT cis rs6570726 0.764 rs376257 chr6:145862949 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7586879 0.593 rs10198356 chr2:25130592 A/G cg01884057 chr2:25150051 NA 0.36 7.1 0.54 8.43e-11 Body mass index; TGCT cis rs7017914 0.905 rs3098873 chr8:71932586 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs185694 0.779 rs639234 chr13:30893984 G/A cg07600127 chr13:30881527 KATNAL1 -0.76 -6.17 -0.48 8.73e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs1971762 0.762 rs4759282 chr12:54072435 C/A cg09709951 chr12:54017699 ATF7 0.33 5.06 0.41 1.48e-6 Height; TGCT cis rs9303401 0.659 rs3809724 chr17:57061238 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.69 6.41 0.5 2.7e-9 Cognitive test performance; TGCT cis rs6542838 0.641 rs13005124 chr2:99527680 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.26 -0.43 6.04e-7 Fear of minor pain; TGCT cis rs2224391 0.534 rs2753228 chr6:5246623 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs7668190 0.924 rs2114039 chr4:55092626 T/C cg17187183 chr4:55093834 PDGFRA 0.43 5.99 0.47 2.1e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs2153535 0.580 rs9393016 chr6:8458573 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg17554472 chr22:41940697 POLR3H -0.49 -5.05 -0.41 1.55e-6 Vitiligo; TGCT cis rs4654899 0.931 rs3767241 chr1:21166144 C/T cg01072550 chr1:21505969 NA 0.5 7.75 0.57 2.84e-12 Superior frontal gyrus grey matter volume; TGCT cis rs9318086 0.648 rs9510927 chr13:24467641 T/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.83 9.04 0.63 2.62e-15 Myopia (pathological); TGCT cis rs910316 1.000 rs175449 chr14:75590846 A/T cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.71e-6 Height; TGCT cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg00786635 chr1:25594202 NA 0.54 5.78 0.46 5.67e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 10.59 0.69 4.52e-19 Colorectal cancer; TGCT cis rs6988636 0.710 rs73339626 chr8:124142757 A/G cg22384356 chr8:124195192 FAM83A -0.42 -4.59 -0.38 1.06e-5 Urinary uromodulin levels; TGCT cis rs6061231 0.761 rs2427312 chr20:60970591 C/T cg24112000 chr20:60950667 NA -0.41 -4.51 -0.38 1.5e-5 Colorectal cancer; TGCT cis rs9399135 0.967 rs6929661 chr6:135328792 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs12681287 0.571 rs13254675 chr8:87353594 C/T cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs921968 0.541 rs832798 chr2:219464810 G/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg02353165 chr6:42928485 GNMT 0.66 5.84 0.46 4.31e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7582180 0.739 rs11687352 chr2:100919888 A/C cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.89e-7 Intelligence (multi-trait analysis); TGCT cis rs6669919 0.647 rs4951753 chr1:211671794 C/T cg26515805 chr1:211431828 RCOR3 -0.45 -4.56 -0.38 1.2e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6671200 0.510 rs35556400 chr1:95916885 G/A cg03123541 chr1:95699097 RWDD3 0.92 5.6 0.45 1.34e-7 Stearic acid (18:0) levels; TGCT cis rs2839186 0.500 rs13049893 chr21:47707054 C/T cg12516959 chr21:47718080 NA -0.33 -4.75 -0.39 5.53e-6 Testicular germ cell tumor; TGCT cis rs7681440 0.801 rs1372513 chr4:90790237 G/A cg20003494 chr4:90757398 SNCA -0.6 -5.54 -0.45 1.73e-7 Dementia with Lewy bodies; TGCT cis rs8050907 0.744 rs28680621 chr16:4518994 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs7917772 0.565 rs61869210 chr10:104437175 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.68 5.8 0.46 5.3e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514475 0.526 rs12201389 chr6:137955452 G/A cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs12497850 0.865 rs7649458 chr3:48920127 C/T cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg03404566 chr17:6899310 ALOX12 -0.42 -4.9 -0.4 2.95e-6 Tonsillectomy; TGCT cis rs7647973 0.961 rs10154992 chr3:49276077 C/T cg07636037 chr3:49044803 WDR6 0.67 5.41 0.44 3.15e-7 Menarche (age at onset); TGCT cis rs909002 0.800 rs968335 chr1:32085776 G/A cg11573219 chr1:32083031 HCRTR1 -0.45 -5.86 -0.47 3.83e-8 Intelligence (multi-trait analysis); TGCT cis rs6674176 0.660 rs12726706 chr1:44399942 G/A cg12908607 chr1:44402522 ARTN -0.73 -9.11 -0.63 1.78e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9611519 1.000 rs2273085 chr22:41615376 C/T cg03806693 chr22:41940476 POLR3H -0.66 -6.3 -0.49 4.65e-9 Neuroticism; TGCT cis rs9399135 0.967 rs59329760 chr6:135342437 G/A cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs7845219 0.544 rs2945554 chr8:95939594 C/A cg09323728 chr8:95962352 TP53INP1 -0.4 -4.6 -0.38 1.04e-5 Type 2 diabetes; TGCT cis rs4888262 0.564 rs8062404 chr16:74611675 T/C cg01733217 chr16:74700730 RFWD3 0.75 7.54 0.56 8.8e-12 Testicular germ cell tumor; TGCT cis rs791357 0.840 rs791361 chr5:173208633 A/C cg04561637 chr5:172480106 NA -0.26 -4.6 -0.38 1.04e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs7726839 0.540 rs72703087 chr5:598029 C/T cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs17376456 0.825 rs10036024 chr5:93074804 C/A cg25358565 chr5:93447407 FAM172A 0.89 5.88 0.47 3.58e-8 Diabetic retinopathy; TGCT cis rs7647973 1.000 rs3448 chr3:49396751 T/C cg07636037 chr3:49044803 WDR6 0.71 5.76 0.46 6.26e-8 Menarche (age at onset); TGCT cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg17554472 chr22:41940697 POLR3H -0.47 -4.91 -0.4 2.87e-6 Vitiligo; TGCT cis rs1059312 0.808 rs4482069 chr12:129294252 G/C cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs185694 0.857 rs200510 chr13:30904134 A/G cg07600127 chr13:30881527 KATNAL1 -0.54 -4.7 -0.39 6.94e-6 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs10883723 0.773 rs11191303 chr10:104255158 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 5.92 0.47 2.92e-8 Alzheimer's disease; TGCT trans rs941408 0.963 rs1640267 chr19:2789337 T/C cg22153745 chr1:153894579 GATAD2B -0.68 -6.78 -0.52 4.46e-10 Total cholesterol levels; TGCT cis rs8038465 0.967 rs61012032 chr15:73973978 C/T cg15420318 chr15:73925796 NPTN 0.7 6.53 0.51 1.56e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8077889 0.869 rs11713 chr17:41845824 A/G cg26893861 chr17:41843967 DUSP3 -1.06 -12.71 -0.75 3.21e-24 Triglycerides; TGCT cis rs12142240 0.698 rs1135460 chr1:46815970 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs4788570 0.584 rs6499534 chr16:71755278 C/G cg06353428 chr16:71660113 MARVELD3 1.56 12.67 0.75 4.05e-24 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs1577470 chr6:8462426 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs8070624 0.502 rs12951376 chr17:17752809 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.7 6.36 0.5 3.52e-9 Total body bone mineral density; TGCT cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg06618935 chr21:46677482 NA -0.37 -5.83 -0.46 4.48e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2663905 0.611 rs1509559 chr15:81391411 G/A cg18837035 chr15:81426597 C15orf26 -0.6 -5.42 -0.44 2.98e-7 QT interval (drug interaction); TGCT cis rs7178424 0.846 rs13379492 chr15:62184636 T/A cg00456672 chr15:62358751 C2CD4A -0.31 -4.6 -0.38 1.02e-5 Height; TGCT cis rs7772486 0.846 rs2748499 chr6:146315002 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.13 0.42 1.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2204008 0.591 rs11495396 chr12:38380182 C/T cg13010199 chr12:38710504 ALG10B 0.59 4.64 0.38 8.86e-6 Bladder cancer; TGCT cis rs2836974 0.666 rs12626405 chr21:40663121 G/T cg06238570 chr21:40685208 BRWD1 -0.82 -9.26 -0.64 7.63e-16 Cognitive function; TGCT cis rs13191362 0.872 rs13194619 chr6:163203657 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.77 0.52 4.6e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11792861 0.781 rs72607158 chr9:111763010 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.51 4.73 0.39 5.99e-6 Menarche (age at onset); TGCT cis rs6089584 0.821 rs4925332 chr20:60604639 C/T cg16423285 chr20:60520624 NA -0.62 -6.91 -0.53 2.25e-10 Body mass index; TGCT cis rs10875746 0.951 rs11168433 chr12:48558064 C/G cg20731937 chr12:48336164 NA 0.64 5.13 0.42 1.07e-6 Longevity (90 years and older); TGCT cis rs9788682 1.000 rs9788682 chr15:78802586 A/G cg24631222 chr15:78858424 CHRNA5 -0.87 -7.92 -0.58 1.15e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs79057730 0.599 rs35928068 chr7:805363 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.66 6.27 0.49 5.39e-9 Initial pursuit acceleration; TGCT cis rs9291683 0.588 rs17246745 chr4:9994583 T/C cg11266682 chr4:10021025 SLC2A9 0.68 9.45 0.65 2.67e-16 Bone mineral density; TGCT cis rs554111 0.656 rs6695218 chr1:21190512 A/C cg01072550 chr1:21505969 NA 0.34 5.11 0.42 1.19e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs2688608 0.587 rs2894040 chr10:75478159 A/C cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs595982 0.527 rs35087747 chr19:49377918 G/T cg17863274 chr19:49399704 TULP2 -0.55 -7.9 -0.58 1.31e-12 Red cell distribution width; TGCT cis rs9522267 0.535 rs9515454 chr13:112236885 A/G cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs6952809 0.532 rs6461361 chr7:2432167 A/G cg23289794 chr7:2394357 EIF3B -0.82 -7.14 -0.54 7.04e-11 Multiple sclerosis; TGCT cis rs9393692 0.846 rs7771202 chr6:26279907 A/G cg05868516 chr6:26286170 HIST1H4H 0.63 5.91 0.47 3.02e-8 Educational attainment; TGCT cis rs7159131 0.502 rs17765618 chr14:36969462 G/T cg07345734 chr14:36986363 NKX2-1 -0.55 -4.68 -0.39 7.39e-6 Intelligence (multi-trait analysis); TGCT cis rs12291225 0.753 rs1431374 chr11:14303975 T/C cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs9291683 0.588 rs6857693 chr4:10018435 G/A cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Bone mineral density; TGCT cis rs2120019 1.000 rs12901243 chr15:75374233 C/T cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs7584330 0.518 rs74003105 chr2:238446851 T/C cg14458575 chr2:238380390 NA 0.43 4.51 0.38 1.48e-5 Prostate cancer; TGCT cis rs1670533 0.932 rs6599276 chr4:1056827 T/C cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs2456568 0.802 rs11020585 chr11:93638493 A/C cg16099599 chr11:93583650 C11orf90 0.39 4.91 0.4 2.76e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg10108389 chr3:44770937 ZNF501 0.46 4.63 0.38 9.02e-6 Depressive symptoms; TGCT trans rs11088226 0.681 rs2833912 chr21:33949822 G/A cg09050820 chr6:167586206 TCP10L2 0.76 7.31 0.55 2.88e-11 Gastritis; TGCT cis rs2439831 0.867 rs16957630 chr15:43642780 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs7940866 0.845 rs1433976 chr11:130875123 C/T cg05962950 chr11:130786565 SNX19 -0.62 -6.42 -0.5 2.64e-9 Schizophrenia; TGCT trans rs916888 0.821 rs199504 chr17:44861003 C/T cg07870213 chr5:140052090 DND1 -0.62 -7.46 -0.56 1.33e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3617 0.598 rs56214994 chr3:52878600 G/C cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7909074 0.933 rs879073 chr10:45399882 C/G cg04218760 chr10:45406644 TMEM72 -0.27 -5.35 -0.43 4.05e-7 Mean corpuscular volume; TGCT cis rs6684514 1.000 rs2273832 chr1:156233143 A/G cg20302342 chr1:156215951 PAQR6 0.35 4.57 0.38 1.17e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10504229 1.000 rs111915672 chr8:58191665 T/C cg08280861 chr8:58055591 NA 0.36 4.8 0.4 4.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs2839186 0.749 rs62226488 chr21:47710517 C/T cg13732083 chr21:47605072 C21orf56 0.34 4.48 0.37 1.68e-5 Testicular germ cell tumor; TGCT cis rs2657888 0.965 rs2657905 chr12:56935402 T/A cg23932658 chr12:57637574 STAC3 0.48 4.57 0.38 1.18e-5 Adiponectin levels; TGCT cis rs35000415 0.938 rs34381587 chr7:128666825 A/G cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs938554 0.513 rs3775946 chr4:9995256 A/G cg11266682 chr4:10021025 SLC2A9 0.53 4.7 0.39 6.68e-6 Blood metabolite levels; TGCT trans rs116975820 0.698 rs11181497 chr12:42814962 A/G cg26084949 chr14:75039090 LTBP2 -0.76 -6.73 -0.52 5.51e-10 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs12541335 0.579 rs59283125 chr8:22212311 G/A cg18135555 chr8:22132992 PIWIL2 0.31 6.17 0.48 9.09e-9 Hypertriglyceridemia; TGCT cis rs526631 0.564 rs10896051 chr11:65578759 C/T cg04055107 chr11:65626734 MUS81;CFL1 -0.67 -6.01 -0.48 1.9e-8 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs910316 0.712 rs175015 chr14:75457075 A/C cg08847533 chr14:75593920 NEK9 -0.84 -8.91 -0.62 5.45e-15 Height; TGCT cis rs2299587 0.554 rs3853531 chr8:17748920 C/T cg04898035 chr8:17640624 MTUS1 0.2 4.63 0.38 9.19e-6 Economic and political preferences; TGCT cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg05025164 chr4:1340916 KIAA1530 -0.56 -4.81 -0.4 4.29e-6 Obesity-related traits; TGCT cis rs992157 0.735 rs13430006 chr2:219113089 A/C cg00012203 chr2:219082015 ARPC2 -0.81 -10.19 -0.68 4.34e-18 Colorectal cancer; TGCT cis rs6700896 0.522 rs11208719 chr1:66159001 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs514406 0.861 rs1412706 chr1:53237721 G/A cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs7312933 0.584 rs6582395 chr12:42700141 T/C cg19980929 chr12:42632907 YAF2 0.43 5.78 0.46 5.7e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9677476 0.657 rs9679430 chr2:232122482 C/T cg07929768 chr2:232055508 NA -0.32 -5.29 -0.43 5.45e-7 Food antigen IgG levels; TGCT cis rs4663866 0.901 rs2304672 chr2:239186589 C/G cg17283117 chr2:239148619 HES6 -0.99 -4.88 -0.4 3.13e-6 Irritable bowel syndrome; TGCT cis rs4242434 0.927 rs57594397 chr8:22475657 T/C cg03733263 chr8:22462867 KIAA1967 1.15 18.91 0.86 2.43e-38 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs77861329 1.000 rs352148 chr3:52208898 A/G cg08692210 chr3:52188851 WDR51A 0.93 4.91 0.4 2.84e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs11235843 0.602 rs1830069 chr11:73433229 C/G cg18195628 chr11:73498948 MRPL48 -0.64 -4.52 -0.38 1.42e-5 Hand grip strength; TGCT cis rs5769707 0.967 rs4524218 chr22:50018639 G/A cg10356904 chr22:49881777 NA -0.22 -4.52 -0.38 1.4e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7246657 0.722 rs10404031 chr19:38035954 A/G cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs367615 0.704 rs72804385 chr5:108848143 T/C cg17395555 chr5:108820864 NA 0.31 5.72 0.46 7.47e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs11696501 0.688 rs6073833 chr20:44279894 T/G cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs8013055 1.000 rs8013055 chr14:105990620 T/A cg23356831 chr14:105996513 TMEM121 0.35 5.1 0.42 1.22e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7772486 0.727 rs6941429 chr6:145952283 G/A cg05347473 chr6:146136440 FBXO30 0.53 4.97 0.41 2.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4851266 0.898 rs2309812 chr2:100869702 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.21 -0.42 7.59e-7 Educational attainment; TGCT cis rs9868809 0.649 rs3733086 chr3:48699519 C/T cg00383909 chr3:49044727 WDR6 1.13 6.17 0.48 8.69e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs611744 0.967 rs2212704 chr8:109198415 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs478304 0.718 rs1151490 chr11:65390485 A/C cg27068330 chr11:65405492 SIPA1 0.83 8.42 0.6 7.95e-14 Acne (severe); TGCT cis rs73198271 0.751 rs55816468 chr8:8605876 C/A cg06671706 chr8:8559999 CLDN23 -0.36 -4.56 -0.38 1.21e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9393692 0.875 rs2142703 chr6:26289605 A/G cg13736514 chr6:26305472 NA -0.41 -5.77 -0.46 6.09e-8 Educational attainment; TGCT cis rs793571 0.543 rs4775087 chr15:58974904 T/C cg05156742 chr15:59063176 FAM63B 0.49 4.66 0.39 8.19e-6 Schizophrenia; TGCT cis rs6558530 0.932 rs4370560 chr8:1708194 G/A cg09410841 chr8:1729607 CLN8 0.91 10.31 0.68 2.23e-18 Systolic blood pressure; TGCT cis rs2412208 0.545 rs7414485 chr1:7121397 G/A cg20434152 chr1:7120926 CAMTA1 -0.3 -4.93 -0.4 2.56e-6 Survival in sporadic amyotrophic lateral sclerosis; TGCT cis rs433598 0.828 rs163270 chr16:20675829 G/A cg16616769 chr16:19727142 IQCK;C16orf88 -0.2 -4.47 -0.37 1.71e-5 Schizophrenia; TGCT cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg23758822 chr17:41437982 NA 0.75 7.03 0.53 1.22e-10 Menopause (age at onset); TGCT cis rs7659604 0.521 rs13114801 chr4:122670855 C/A cg19748678 chr4:122722346 EXOSC9 -0.51 -4.93 -0.4 2.58e-6 Type 2 diabetes; TGCT cis rs6461049 0.646 rs3778970 chr7:2143208 C/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.41 -0.5 2.79e-9 Schizophrenia; TGCT cis rs4803468 1.000 rs284654 chr19:41928724 G/A cg09537434 chr19:41945824 ATP5SL -0.93 -10.91 -0.7 7.92e-20 Height; TGCT cis rs2180341 0.960 rs6900074 chr6:127685893 A/G cg27446573 chr6:127587934 RNF146 1.15 10.91 0.7 7.65e-20 Breast cancer; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg10819733 chr22:24237672 NA -0.29 -4.83 -0.4 3.97e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12135062 1.000 rs12135062 chr1:3103312 A/C cg25382214 chr1:3105252 PRDM16 0.27 4.76 0.39 5.37e-6 Migraine; TGCT cis rs2299587 0.554 rs17634704 chr8:17753306 A/G cg04898035 chr8:17640624 MTUS1 -0.21 -4.72 -0.39 6.17e-6 Economic and political preferences; TGCT cis rs68170813 0.559 rs12536603 chr7:107002573 T/C cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs12908161 1.000 rs12910012 chr15:85298662 T/C cg12863693 chr15:85201151 NMB 0.43 5.06 0.41 1.46e-6 Schizophrenia; TGCT cis rs9993613 0.875 rs1481831 chr4:73480019 T/C cg15102770 chr4:73434591 ADAMTS3 0.52 4.89 0.4 3.07e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs7917772 0.582 rs4919663 chr10:104363293 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1801251 0.778 rs709933 chr2:233733144 G/A cg25237894 chr2:233734115 C2orf82 -0.32 -6.23 -0.49 6.73e-9 Coronary artery disease; TGCT cis rs7940866 0.903 rs1820353 chr11:130870765 A/G cg12179176 chr11:130786555 SNX19 0.48 4.61 0.38 9.97e-6 Schizophrenia; TGCT cis rs7923452 0.688 rs117895480 chr10:30788921 A/G cg18806716 chr10:30721971 MAP3K8 0.73 6.26 0.49 5.84e-9 Itch intensity from mosquito bite; TGCT cis rs3820068 0.705 rs11583306 chr1:15860803 A/G cg05660106 chr1:15850417 CASP9 -1.14 -13.98 -0.78 2.98e-27 Systolic blood pressure; TGCT cis rs7617773 0.817 rs11130162 chr3:48297611 A/G cg11946769 chr3:48343235 NME6 0.74 7.03 0.53 1.21e-10 Coronary artery disease; TGCT trans rs17685 0.753 rs8200 chr7:75696606 C/G cg19862616 chr7:65841803 NCRNA00174 -0.52 -9.14 -0.63 1.49e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs10489202 0.634 rs6427119 chr1:168074145 A/G cg24449463 chr1:168025552 DCAF6 0.52 5.49 0.44 2.12e-7 Schizophrenia; TGCT cis rs7027203 1.000 rs34624092 chr9:96523092 G/A cg14598338 chr9:96623480 NA 0.58 8.57 0.61 3.49e-14 DNA methylation (variation); TGCT cis rs6831352 0.918 rs2602896 chr4:100046207 C/T cg12011299 chr4:100065546 ADH4 -0.44 -4.98 -0.41 2.12e-6 Alcohol dependence; TGCT cis rs9790314 1.000 rs9790314 chr3:161019558 T/C cg03342759 chr3:160939853 NMD3 -0.43 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs9467711 0.651 rs13210041 chr6:26037601 G/A cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs975752 0.867 rs66728174 chr10:102020626 C/T cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs79387448 0.745 rs1880000 chr2:103099953 T/C cg09003973 chr2:102972529 NA 0.89 5.92 0.47 2.95e-8 Gut microbiota (bacterial taxa); TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs7226408 0.857 rs55809464 chr18:34608316 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2637266 0.739 rs2579736 chr10:78427688 G/A cg18941641 chr10:78392320 NA 0.4 4.91 0.4 2.79e-6 Pulmonary function; TGCT trans rs629535 0.748 rs58675625 chr8:70034924 T/C cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT trans rs1496653 0.602 rs35408638 chr3:23454175 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs1232027 0.700 rs1650694 chr5:79952426 G/A cg07324116 chr5:80060102 MSH3 -0.25 -4.61 -0.38 9.94e-6 Huntington's disease progression; TGCT cis rs9914544 1.000 rs7223231 chr17:18811846 C/T cg26306683 chr17:18585705 ZNF286B 0.58 5.18 0.42 8.8e-7 Educational attainment (years of education); TGCT cis rs8031584 0.918 rs61997138 chr15:31270776 C/T cg08704250 chr15:31115839 NA -0.35 -4.93 -0.4 2.6e-6 Huntington's disease progression; TGCT cis rs3733585 0.699 rs7658170 chr4:9966593 C/T cg11266682 chr4:10021025 SLC2A9 0.57 7.65 0.57 4.88e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9902453 0.716 rs3098949 chr17:27978694 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 8.2 0.59 2.54e-13 Coffee consumption (cups per day); TGCT cis rs4319547 0.956 rs7316149 chr12:123063912 G/A cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.43 -0.44 2.83e-7 Body mass index; TGCT cis rs11031096 0.505 rs10835743 chr11:4226692 C/T cg18678763 chr11:4115507 RRM1 -0.42 -5.37 -0.43 3.81e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9372498 0.572 rs10484289 chr6:118827836 T/C cg07617317 chr6:118971624 C6orf204 0.51 5.42 0.44 3.01e-7 Diastolic blood pressure; TGCT cis rs2338224 1.000 rs4703888 chr5:71746042 A/T cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs4240897 0.935 rs4846082 chr1:12042443 C/T cg13216073 chr1:12042593 MFN2 0.19 5.73 0.46 7.18e-8 Tuberculosis; TGCT cis rs7226408 0.857 rs72885296 chr18:34451891 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg05738196 chr6:26577821 NA 0.88 10.71 0.69 2.37e-19 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.908 rs55855805 chr2:43808490 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7523273 0.597 rs2724384 chr1:207930203 G/A cg22525895 chr1:207977042 MIR29B2 0.45 6.59 0.51 1.14e-9 Schizophrenia; TGCT cis rs4727027 0.870 rs13237714 chr7:148884083 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.77 0.39 5.16e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs80282103 0.618 rs1079389 chr10:1161980 A/G cg08668510 chr10:1095578 IDI1 1.06 5.03 0.41 1.7e-6 Glomerular filtration rate (creatinine); TGCT trans rs3774749 0.565 rs2518795 chr3:50208819 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.79 7.68 0.57 4.11e-12 Intelligence (multi-trait analysis); TGCT cis rs11585357 0.947 rs72646789 chr1:17610030 C/T cg08277548 chr1:17600880 PADI3 -0.97 -9.95 -0.67 1.7e-17 Hair shape; TGCT cis rs208520 0.690 rs1738970 chr6:66809491 T/G cg07460842 chr6:66804631 NA -0.93 -9.66 -0.66 8.29e-17 Exhaled nitric oxide output; TGCT cis rs295140 0.585 rs4233996 chr2:201131228 A/T cg23649088 chr2:200775458 C2orf69 -0.29 -5.02 -0.41 1.77e-6 QT interval; TGCT cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.68 0.61 1.9e-14 Platelet count; TGCT cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg18404041 chr3:52824283 ITIH1 0.21 4.63 0.38 9.15e-6 Bipolar disorder; TGCT cis rs7216064 1.000 rs7224923 chr17:65842265 T/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4973397 0.810 rs12999051 chr2:232276992 T/A cg09339159 chr2:232260559 B3GNT7 0.54 4.68 0.39 7.25e-6 Anti-saccade response; TGCT cis rs16921914 0.559 rs2985140 chr11:31315886 C/T cg26647111 chr11:31128758 NA 0.33 4.74 0.39 5.71e-6 Bone mineral density (spine); TGCT cis rs2019137 0.936 rs3811059 chr2:113962071 C/T cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs66561647 0.719 rs7812386 chr8:128937609 C/A cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.73 0.39 5.97e-6 Hemoglobin concentration; TGCT cis rs7940866 0.740 rs2162060 chr11:130830763 A/G cg12179176 chr11:130786555 SNX19 0.57 5.4 0.44 3.23e-7 Schizophrenia; TGCT cis rs9611565 0.512 rs139572 chr22:42214532 C/T cg17554472 chr22:41940697 POLR3H -0.46 -4.69 -0.39 7.09e-6 Vitiligo; TGCT cis rs72781680 1.000 rs72788278 chr2:24095285 A/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs7772486 0.686 rs1292334 chr6:145968288 A/G cg05347473 chr6:146136440 FBXO30 0.5 4.65 0.39 8.34e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1580019 0.587 rs34488151 chr7:32548146 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.96 0.41 2.25e-6 Cognitive ability; TGCT cis rs7666738 0.830 rs59751489 chr4:98933802 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg11502198 chr6:26597334 ABT1 0.55 4.9 0.4 2.92e-6 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs693597 chr11:95589629 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.63 0.61 2.51e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12210905 0.688 rs12374607 chr6:27343620 A/G cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs1062177 1.000 rs72802204 chr5:151183183 T/C cg12924095 chr5:151150029 G3BP1 0.35 5.02 0.41 1.77e-6 Preschool internalizing problems; TGCT cis rs67460515 0.892 rs11711695 chr3:161057593 A/G cg03342759 chr3:160939853 NMD3 -0.47 -5.12 -0.42 1.12e-6 Parkinson's disease; TGCT cis rs6684514 1.000 rs10494304 chr1:156285764 C/G cg16558208 chr1:156270281 VHLL -0.48 -9.6 -0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7726839 0.540 rs7434 chr5:660804 A/G cg16624210 chr5:671434 TPPP -0.41 -4.84 -0.4 3.74e-6 Obesity-related traits; TGCT trans rs916888 0.773 rs199443 chr17:44819565 C/T cg22968622 chr17:43663579 NA 1.3 11.87 0.73 3.46e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10904887 1.000 rs7900163 chr10:17188637 C/T cg01003015 chr10:17271136 VIM -0.65 -6.01 -0.47 1.93e-8 Telomere length; TGCT cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg08219700 chr8:58056026 NA 0.39 4.73 0.39 5.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs4285028 0.747 rs77570895 chr3:121384565 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.94 -7.35 -0.55 2.36e-11 Multiple sclerosis; TGCT cis rs56176327 0.532 rs9849038 chr3:49771990 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Intelligence (multi-trait analysis); TGCT cis rs34014631 1.000 rs114132090 chr10:103590342 C/A cg22630918 chr10:102748988 C10orf2 0.44 4.85 0.4 3.57e-6 Coronary artery calcification; TGCT cis rs9486719 1.000 rs3798289 chr6:97023632 T/C cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs66561647 0.857 rs12548939 chr8:128958771 C/T cg11792826 chr8:129160931 MIR1208 0.22 4.7 0.39 6.94e-6 Hemoglobin concentration; TGCT cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg17264618 chr3:40429014 ENTPD3 0.33 4.82 0.4 4.12e-6 Renal cell carcinoma; TGCT cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs12142240 0.667 rs45524035 chr1:46862780 C/T cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs9916302 0.904 rs7501488 chr17:37576417 T/G cg15445000 chr17:37608096 MED1 0.34 4.8 0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs765787 0.530 rs3759892 chr15:45542709 A/G cg24006582 chr15:45444508 DUOX1 0.24 5.3 0.43 5.13e-7 Uric acid levels; TGCT cis rs10791097 0.720 rs6590515 chr11:130733365 A/G cg05962950 chr11:130786565 SNX19 -0.9 -11.61 -0.72 1.52e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2235642 0.821 rs2281236 chr16:1603576 G/A cg10465839 chr16:1584050 IFT140;TMEM204 -0.31 -5.23 -0.43 7.02e-7 Coronary artery disease; TGCT cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.75 -0.39 5.61e-6 Diastolic blood pressure; TGCT cis rs1023500 0.596 rs133352 chr22:42434022 C/A cg05082376 chr22:42548792 NA -0.23 -5.43 -0.44 2.81e-7 Schizophrenia; TGCT cis rs938554 0.744 rs13129697 chr4:9926967 T/G cg11266682 chr4:10021025 SLC2A9 -0.47 -4.83 -0.4 3.9e-6 Blood metabolite levels; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg12419862 chr22:24373484 LOC391322 -0.78 -8.1 -0.59 4.41e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2832191 0.967 rs2898160 chr21:30487496 A/G cg24692254 chr21:30365293 RNF160 -0.83 -8.71 -0.62 1.58e-14 Dental caries; TGCT cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs13102973 0.682 rs6535054 chr4:135886055 A/C cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs2439831 1.000 rs28666488 chr15:43741090 G/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs11172134 0.532 rs1800168 chr12:57592557 A/G cg19258868 chr12:57585184 LRP1 -0.3 -6.08 -0.48 1.39e-8 Urate levels in overweight individuals; TGCT cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs11711311 1.000 rs28394480 chr3:113485143 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs2692947 0.673 rs3111873 chr2:96781986 G/C cg22654517 chr2:96458247 NA -0.22 -4.76 -0.39 5.19e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs8020441 0.541 rs72681665 chr14:51167012 C/A cg04730355 chr14:51134070 SAV1 1.11 7.23 0.54 4.26e-11 Cognitive performance; TGCT cis rs10883723 0.737 rs7074444 chr10:104249922 A/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs704 0.726 rs11080055 chr17:26649724 A/C cg10342447 chr17:26645325 TMEM97 -0.56 -5.5 -0.44 2.03e-7 Osteoprotegerin levels; TGCT cis rs72781680 0.528 rs56258075 chr2:24104256 C/G cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs1420338 1.000 rs4723351 chr7:34155813 T/G cg01275685 chr7:34179230 BMPER -0.26 -4.83 -0.4 3.89e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2832191 0.633 rs2832166 chr21:30462395 G/C cg24692254 chr21:30365293 RNF160 0.94 10.29 0.68 2.51e-18 Dental caries; TGCT cis rs7772486 0.686 rs857883 chr6:145969214 G/T cg23711669 chr6:146136114 FBXO30 -0.86 -9.6 -0.65 1.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9902453 1.000 rs4465650 chr17:28396721 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.54 0.51 1.44e-9 Coffee consumption (cups per day); TGCT cis rs6089829 0.889 rs6090206 chr20:61668363 G/A cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT trans rs9388451 0.807 rs1268065 chr6:126042783 G/A cg05039488 chr6:79577232 IRAK1BP1 0.7 7.4 0.55 1.84e-11 Brugada syndrome; TGCT cis rs1023500 0.596 rs133369 chr22:42463814 C/T cg15557168 chr22:42548783 NA -0.22 -5.6 -0.45 1.33e-7 Schizophrenia; TGCT cis rs601339 1.000 rs11059384 chr12:123170301 C/A cg11919336 chr12:123188078 GPR109A 0.64 7.49 0.56 1.1e-11 Adiponectin levels; TGCT cis rs1982963 0.587 rs2516593 chr14:52503369 T/C cg10843707 chr14:52510701 NID2 -0.36 -7.22 -0.54 4.54e-11 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6570726 0.791 rs427128 chr6:145865917 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs6050632 chr20:25432601 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11098499 0.754 rs4443261 chr4:120249301 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs4148883 0.689 rs1800760 chr4:100065626 A/T cg12011299 chr4:100065546 ADH4 0.39 5.89 0.47 3.35e-8 Alcohol dependence; TGCT cis rs807669 0.903 rs2854643 chr22:19189706 T/C cg02655711 chr22:19163373 SLC25A1 0.4 9.32 0.64 5.62e-16 Metabolite levels; TGCT cis rs1372520 0.684 rs1442144 chr4:90736113 T/C cg01966878 chr4:90757139 SNCA -0.31 -4.91 -0.4 2.85e-6 Neuroticism; TGCT cis rs7216064 0.655 rs8078543 chr17:66037251 G/T cg12091567 chr17:66097778 LOC651250 1.08 8.86 0.62 7.21e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9952991 0.883 rs2542148 chr18:12777573 C/G cg24737193 chr18:12778029 NA 0.53 5.93 0.47 2.8e-8 Inflammatory skin disease; TGCT cis rs78487399 0.808 rs6752964 chr2:43754655 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7582180 0.764 rs12999779 chr2:100924321 T/G cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs870825 0.616 rs10428373 chr4:185639002 A/G cg21366198 chr4:185655624 MLF1IP -0.67 -4.95 -0.41 2.37e-6 Blood protein levels; TGCT cis rs10193935 0.901 rs10200353 chr2:42509554 A/G cg27598129 chr2:42591480 NA -0.41 -5.57 -0.45 1.53e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9325144 0.555 rs2387847 chr12:38687434 C/T cg26384229 chr12:38710491 ALG10B 0.66 6.12 0.48 1.11e-8 Morning vs. evening chronotype; TGCT cis rs55883249 1.000 rs11676903 chr2:9763201 G/C cg23886495 chr2:9695866 ADAM17 0.78 4.66 0.39 8.08e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs875971 0.660 rs801211 chr7:66015689 T/G cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs2228479 0.867 rs12930056 chr16:89946649 C/A cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs12142240 0.660 rs7520497 chr1:46824919 C/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg06873352 chr17:61820015 STRADA -0.55 -6.13 -0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs10484885 0.887 rs114928443 chr6:90602455 A/T cg13799429 chr6:90582589 CASP8AP2 -0.43 -4.46 -0.37 1.8e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1784581 0.588 rs7758559 chr6:162438635 G/T cg17173639 chr6:162384350 PARK2 0.42 6.95 0.53 1.8e-10 Itch intensity from mosquito bite; TGCT cis rs12497850 0.931 rs13316620 chr3:49045355 T/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 3e-7 Parkinson's disease; TGCT cis rs1670533 1.000 rs6839931 chr4:1053172 A/G cg20887711 chr4:1340912 KIAA1530 0.7 5.65 0.45 1.03e-7 Recombination rate (females); TGCT cis rs854765 0.647 rs854808 chr17:18006634 C/T cg04398451 chr17:18023971 MYO15A -0.38 -6.48 -0.5 1.91e-9 Total body bone mineral density; TGCT cis rs3892630 0.824 rs2287882 chr19:33332952 C/T cg22980127 chr19:33182716 NUDT19 0.67 4.91 0.4 2.85e-6 Red blood cell traits; TGCT cis rs6754311 0.517 rs1865452 chr2:136539330 C/T cg07169764 chr2:136633963 MCM6 0.89 7.96 0.58 9.17e-13 Mosquito bite size; TGCT cis rs7954584 0.545 rs12824593 chr12:122374108 G/A cg21171335 chr12:122356390 WDR66 0.7 7.03 0.53 1.24e-10 Mean corpuscular volume; TGCT cis rs11190604 1.000 rs2295779 chr10:102296061 A/G cg16342193 chr10:102329863 NA -0.4 -5.46 -0.44 2.53e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9393777 0.513 rs13195210 chr6:26646521 C/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs28374715 0.528 rs7178360 chr15:41631175 T/A cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.93 -0.8 1.76e-29 Ulcerative colitis; TGCT cis rs17221829 0.617 rs1844194 chr11:89389367 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg17178900 chr1:205818956 PM20D1 0.59 7.37 0.55 2.06e-11 Menarche (age at onset); TGCT cis rs11190604 1.000 rs2003284 chr10:102202338 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6952808 0.501 rs4721429 chr7:2171704 T/C cg22963979 chr7:1858916 MAD1L1 -0.37 -5.77 -0.46 5.99e-8 Bipolar disorder and schizophrenia; TGCT cis rs1903068 1.000 rs9312658 chr4:56005526 C/A cg01777861 chr4:56023843 NA 0.56 6.54 0.51 1.45e-9 Endometriosis; TGCT cis rs7959452 0.535 rs7133487 chr12:69774377 G/A cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs6484504 0.532 rs2774403 chr11:31320530 A/T cg26647111 chr11:31128758 NA 0.31 4.48 0.37 1.66e-5 Red blood cell count; TGCT cis rs9902453 1.000 rs7207021 chr17:28400516 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -6.77 -0.52 4.47e-10 Coffee consumption (cups per day); TGCT cis rs763014 0.932 rs34498660 chr16:666149 A/G cg00908189 chr16:619842 PIGQ 0.87 10.61 0.69 4.21e-19 Height; TGCT cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg07507251 chr3:52567010 NT5DC2 0.46 6.55 0.51 1.41e-9 Bipolar disorder; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs7582180 0.764 rs11686293 chr2:100922830 C/T cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg03517284 chr6:25882590 NA -0.9 -8.6 -0.61 2.87e-14 Intelligence (multi-trait analysis); TGCT cis rs617219 0.710 rs16876598 chr5:78573970 T/C cg05890484 chr5:78407552 BHMT -0.34 -4.63 -0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs526231 0.819 rs35803 chr5:102606942 A/G cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs9926296 0.605 rs6500453 chr16:89858657 C/G cg21285383 chr16:89894308 SPIRE2 0.44 7.03 0.53 1.23e-10 Vitiligo; TGCT cis rs4919044 0.688 rs59539045 chr10:94776594 C/A cg05127821 chr10:94822908 CYP26C1 -0.77 -5.03 -0.41 1.71e-6 Coronary artery disease; TGCT cis rs2387326 1.000 rs34558168 chr10:129932106 T/C cg03458096 chr10:129105057 DOCK1 -0.3 -4.67 -0.39 7.78e-6 Select biomarker traits; TGCT cis rs921968 0.584 rs2305833 chr2:219305404 G/C cg02176678 chr2:219576539 TTLL4 0.37 5.34 0.43 4.32e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg12419862 chr22:24373484 LOC391322 -0.8 -8.43 -0.6 7.54e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs909674 0.909 rs1557541 chr22:39851970 C/A cg24399712 chr22:39784796 NA -1.05 -11.09 -0.71 2.82e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.87 0.47 3.73e-8 Alzheimer's disease; TGCT cis rs9653442 0.593 rs4851273 chr2:100848321 A/G cg22139774 chr2:100720529 AFF3 -0.38 -5.88 -0.47 3.5e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs10540 1.000 rs61742833 chr11:490035 C/T cg03352830 chr11:487213 PTDSS2 0.32 5.46 0.44 2.44e-7 Body mass index; TGCT cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg03517284 chr6:25882590 NA 0.52 4.67 0.39 7.55e-6 Intelligence (multi-trait analysis); TGCT cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg03264133 chr6:25882463 NA -0.6 -5.49 -0.44 2.18e-7 Intelligence (multi-trait analysis); TGCT cis rs12220898 0.749 rs10776553 chr10:50482929 C/T cg12697796 chr10:49954016 WDFY4 0.49 4.44 0.37 2e-5 Inflammatory biomarkers; TGCT cis rs950776 0.518 rs11630349 chr15:78824608 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs11112613 0.713 rs58066965 chr12:105952505 C/G cg03607813 chr12:105948248 NA 0.47 5.72 0.46 7.49e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs1372520 0.684 rs2619355 chr4:90748374 A/C cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs9300255 0.544 rs1790100 chr12:123656725 G/T cg00376283 chr12:123451042 ABCB9 0.72 5.55 0.45 1.65e-7 Neutrophil percentage of white cells; TGCT cis rs7267979 0.966 rs910996 chr20:25264196 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg22166914 chr1:53195759 ZYG11B 0.37 5.95 0.47 2.57e-8 Monocyte count; TGCT cis rs4253772 0.550 rs739164 chr22:46684558 C/T cg24881330 chr22:46731750 TRMU -0.96 -6.38 -0.5 3.18e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs1552244 0.572 rs58223482 chr3:10169746 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT trans rs1814175 0.646 rs61904497 chr11:49883449 A/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs6866344 0.570 rs56236920 chr5:178144617 C/T cg03877680 chr5:178157825 ZNF354A 0.78 6.69 0.51 6.86e-10 Neutrophil percentage of white cells; TGCT cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs826838 1.000 rs1684395 chr12:39083161 T/G cg13010199 chr12:38710504 ALG10B -0.59 -4.89 -0.4 3e-6 Heart rate; TGCT cis rs36051895 0.623 rs6476956 chr9:5261238 A/G cg02405213 chr9:5042618 JAK2 -0.68 -9.0 -0.63 3.29e-15 Pediatric autoimmune diseases; TGCT cis rs6121246 0.567 rs6058189 chr20:30192389 A/G cg13852791 chr20:30311386 BCL2L1 0.69 4.65 0.39 8.44e-6 Mean corpuscular hemoglobin; TGCT cis rs57590327 0.503 rs4856350 chr3:81503374 G/A cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs2836974 0.644 rs11088471 chr21:40699313 A/G cg06238570 chr21:40685208 BRWD1 -0.82 -8.85 -0.62 7.34e-15 Cognitive function; TGCT cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs9486719 0.947 rs12208556 chr6:96903486 C/T cg18709589 chr6:96969512 KIAA0776 -0.67 -5.23 -0.43 7e-7 Migraine;Coronary artery disease; TGCT cis rs11690935 0.959 rs7562356 chr2:172626611 C/G cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT trans rs2688608 0.901 rs2633312 chr10:75631755 T/A cg13918328 chr10:52500089 ASAH2B 0.66 6.85 0.52 3.11e-10 Inflammatory bowel disease; TGCT cis rs875971 0.638 rs3898855 chr7:66036398 G/C cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs7246657 0.943 rs10422074 chr19:37894236 T/C cg18154014 chr19:37997991 ZNF793 0.95 6.61 0.51 1.04e-9 Coronary artery calcification; TGCT cis rs7666738 0.716 rs2865982 chr4:99031661 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6815814 0.950 rs45588337 chr4:38807328 A/G cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs11969893 0.850 rs9498418 chr6:101331838 A/T cg12253828 chr6:101329408 ASCC3 1.07 5.1 0.42 1.25e-6 Economic and political preferences (immigration/crime); TGCT cis rs2439831 0.850 rs16963953 chr15:44081719 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.01 0.47 1.91e-8 Lung cancer in ever smokers; TGCT cis rs854765 0.619 rs6502636 chr17:17983817 A/T cg04398451 chr17:18023971 MYO15A -0.37 -6.51 -0.5 1.71e-9 Total body bone mineral density; TGCT cis rs9308731 0.583 rs7596789 chr2:111932616 G/A cg04202892 chr2:111875749 ACOXL 0.46 5.14 0.42 1.02e-6 Chronic lymphocytic leukemia; TGCT cis rs910187 0.564 rs6124949 chr20:45764370 C/T cg27589058 chr20:45804311 EYA2 -0.33 -6.01 -0.47 1.93e-8 Migraine; TGCT cis rs10782582 0.592 rs7513194 chr1:76382664 A/C cg03433033 chr1:76189801 ACADM 0.46 4.59 0.38 1.08e-5 Daytime sleep phenotypes; TGCT cis rs2658782 0.951 rs72972364 chr11:93122128 C/T cg26827247 chr11:93063208 CCDC67 0.61 4.67 0.39 7.86e-6 Pulmonary function decline; TGCT cis rs7086627 0.515 rs7088877 chr10:82208860 C/G cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs3849570 0.555 rs6790351 chr3:82008988 C/T cg07356753 chr3:81810745 GBE1 -0.62 -5.38 -0.44 3.5e-7 Waist circumference;Body mass index; TGCT cis rs4727027 0.901 rs1534198 chr7:148772323 T/C cg23583168 chr7:148888333 NA -0.69 -8.67 -0.61 2.04e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg20637647 chr7:64974828 NA 0.88 5.34 0.43 4.19e-7 Diabetic kidney disease; TGCT cis rs7772486 0.754 rs864148 chr6:145976675 T/C cg23711669 chr6:146136114 FBXO30 -0.91 -10.25 -0.68 3.12e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs8072100 0.713 rs3871595 chr17:45511388 C/T cg08085267 chr17:45401833 C17orf57 -0.53 -5.93 -0.47 2.77e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs8103278 1.000 rs8108864 chr19:46301671 G/A cg14061069 chr19:46274453 DMPK -0.41 -5.78 -0.46 5.56e-8 Coronary artery disease; TGCT cis rs9611519 1.000 rs5751069 chr22:41627775 C/G cg13695892 chr22:41940480 POLR3H -0.52 -4.78 -0.39 4.81e-6 Neuroticism; TGCT cis rs6582630 0.519 rs8189609 chr12:38281408 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs73198271 1.000 rs4841030 chr8:8607011 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg26531700 chr6:26746687 NA 0.53 5.04 0.41 1.58e-6 Intelligence (multi-trait analysis); TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg21226059 chr5:178986404 RUFY1 -0.62 -7.52 -0.56 9.7e-12 Lung cancer; TGCT cis rs10540 1.000 rs35811812 chr11:498442 G/A cg03352830 chr11:487213 PTDSS2 0.26 4.46 0.37 1.8e-5 Body mass index; TGCT cis rs739496 0.579 rs2106697 chr12:112260065 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.69e-8 Platelet count; TGCT cis rs2153535 0.601 rs7775274 chr6:8530303 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs35883536 0.611 rs72977390 chr1:101107147 C/T cg06223162 chr1:101003688 GPR88 0.34 5.67 0.45 9.44e-8 Monocyte count; TGCT cis rs2072499 0.966 rs6427307 chr1:156190083 A/G cg06970220 chr1:156163860 SLC25A44 0.67 5.98 0.47 2.22e-8 Testicular germ cell tumor; TGCT cis rs2303745 0.841 rs10409801 chr19:17407415 A/G cg10664184 chr19:17420304 DDA1 0.62 4.75 0.39 5.64e-6 Systemic lupus erythematosus; TGCT cis rs1577917 0.917 rs13213603 chr6:86534758 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs1008375 0.933 rs6847966 chr4:17634255 G/A cg18681998 chr4:17616180 MED28 1.07 11.98 0.73 1.97e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3770081 0.826 rs1019591 chr2:86298599 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs6840360 0.638 rs2406974 chr4:152601841 G/A cg17479576 chr4:152424074 FAM160A1 -0.64 -6.59 -0.51 1.16e-9 Intelligence (multi-trait analysis); TGCT cis rs6701037 0.681 rs1057246 chr1:175127534 C/G cg00321850 chr1:175162397 KIAA0040 0.45 5.53 0.44 1.82e-7 Alcohol dependence; TGCT cis rs6831352 0.918 rs13143133 chr4:100054970 A/G cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs2456568 0.548 rs4753113 chr11:93660974 G/A cg26875233 chr11:93583750 C11orf90 -0.41 -4.97 -0.41 2.14e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs11626933 0.959 rs17799226 chr14:90754538 C/T cg14092571 chr14:90743983 NA -0.29 -6.02 -0.48 1.86e-8 Gut microbiota (bacterial taxa); TGCT cis rs7819412 0.811 rs2409691 chr8:10943276 C/T cg27411982 chr8:10470053 RP1L1 -0.21 -4.6 -0.38 1.02e-5 Triglycerides; TGCT cis rs9300255 0.544 rs1727310 chr12:123660510 A/G cg00376283 chr12:123451042 ABCB9 0.74 5.09 0.42 1.27e-6 Neutrophil percentage of white cells; TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg11494091 chr17:61959527 GH2 0.61 14.68 0.8 6.78e-29 Prudent dietary pattern; TGCT cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs17767294 0.614 rs75043119 chr6:28187424 A/C cg08851530 chr6:28072375 NA 1.46 6.76 0.52 4.79e-10 Parkinson's disease; TGCT cis rs4072705 0.967 rs4240486 chr9:127341110 C/T cg13476313 chr9:127244764 NR5A1 0.28 4.5 0.37 1.52e-5 Menarche (age at onset); TGCT cis rs597539 0.652 rs488363 chr11:68658298 C/G cg04772025 chr11:68637568 NA 0.6 6.67 0.51 7.4e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs4942242 1.000 rs9533572 chr13:44234265 A/C cg19169023 chr15:41853346 TYRO3 -0.33 -6.64 -0.51 9.02e-10 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs765787 0.530 rs1706835 chr15:45517884 G/A cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg06675538 chr2:114033490 PAX8;LOC440839 -0.42 -4.65 -0.39 8.23e-6 Lymphocyte counts; TGCT cis rs7918232 0.662 rs10764662 chr10:27300643 T/A cg14442939 chr10:27389572 ANKRD26 0.58 4.63 0.38 9.13e-6 Breast cancer; TGCT cis rs67072384 1.000 rs12294368 chr11:72451239 G/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg18402987 chr7:1209562 NA 0.76 6.47 0.5 2.05e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611565 0.572 rs139569 chr22:42211141 A/G cg06481639 chr22:41940642 POLR3H -0.53 -4.51 -0.38 1.51e-5 Vitiligo; TGCT cis rs933688 1.000 rs6866191 chr5:90746852 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.25 0.6 1.91e-13 Smoking behavior; TGCT cis rs10089 1.000 rs4836367 chr5:127482592 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.64e-13 Ileal carcinoids; TGCT cis rs72945132 0.825 rs2277273 chr11:70223992 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.39 0.55 1.94e-11 Coronary artery disease; TGCT cis rs3820068 0.577 rs9728986 chr1:16040603 G/A cg05660106 chr1:15850417 CASP9 0.67 6.48 0.5 1.96e-9 Systolic blood pressure; TGCT cis rs7528684 0.816 rs2873405 chr1:157692044 T/G cg17134153 chr1:157670328 FCRL3 -0.26 -4.69 -0.39 7e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs2980436 1 rs2980436 chr8:8092025 A/G cg15556689 chr8:8085844 FLJ10661 -0.85 -9.08 -0.63 2.14e-15 Schizophrenia; TGCT cis rs3771570 1.000 rs62186422 chr2:242249499 A/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs9894429 0.604 rs9912071 chr17:79609654 G/A cg18240062 chr17:79603768 NPLOC4 0.84 9.37 0.64 4.28e-16 Eye color traits; TGCT cis rs769267 0.930 rs3794993 chr19:19611550 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.6 0.45 1.31e-7 Tonsillectomy; TGCT cis rs4727027 0.716 rs4727020 chr7:148837317 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.58 5.17 0.42 9.03e-7 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs826838 0.967 rs1684414 chr12:39129553 A/G cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs916888 0.610 rs199454 chr17:44800110 G/A cg17911788 chr17:44343683 NA 0.48 5.71 0.46 7.77e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs853679 0.517 rs17711344 chr6:28077602 A/G cg12963246 chr6:28129442 ZNF389 -0.51 -5.14 -0.42 1.04e-6 Depression; TGCT cis rs6582630 0.576 rs11504369 chr12:38274566 C/T cg26384229 chr12:38710491 ALG10B -0.52 -4.59 -0.38 1.08e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs9291683 0.507 rs6849273 chr4:10021595 C/T cg00071950 chr4:10020882 SLC2A9 0.62 7.35 0.55 2.37e-11 Bone mineral density; TGCT cis rs2456568 0.548 rs10501809 chr11:93666263 C/G cg17595323 chr11:93583763 C11orf90 -0.43 -5.46 -0.44 2.53e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs854765 0.964 rs854762 chr17:18009102 G/A cg09796270 chr17:17721594 SREBF1 -0.26 -5.22 -0.42 7.3e-7 Total body bone mineral density; TGCT cis rs9291683 0.655 rs55941493 chr4:10100341 G/A cg11266682 chr4:10021025 SLC2A9 -0.49 -5.6 -0.45 1.29e-7 Bone mineral density; TGCT cis rs6430585 0.591 rs72970243 chr2:136484232 G/A cg07169764 chr2:136633963 MCM6 0.91 8.33 0.6 1.28e-13 Corneal structure; TGCT cis rs6840360 0.530 rs62327350 chr4:152641202 G/A cg17479576 chr4:152424074 FAM160A1 -0.63 -6.36 -0.5 3.58e-9 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.851 rs12936996 chr17:37665554 A/G cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs6940638 0.688 rs9295730 chr6:27128806 T/C cg26531700 chr6:26746687 NA -0.53 -4.57 -0.38 1.15e-5 Intelligence (multi-trait analysis); TGCT cis rs4478858 0.684 rs7528066 chr1:31749092 C/G cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs10791323 0.559 rs10750549 chr11:133730820 A/G cg03690763 chr11:133734501 NA -0.3 -4.53 -0.38 1.38e-5 Childhood ear infection; TGCT cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.14e-6 Blood metabolite levels; TGCT cis rs45509595 0.749 rs401763 chr6:27782528 T/C cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.24e-6 Breast cancer; TGCT cis rs1401999 0.714 rs1000002 chr3:183635768 A/G cg01324343 chr3:183735012 ABCC5 -0.67 -8.25 -0.6 1.93e-13 Anterior chamber depth; TGCT cis rs56176327 0.600 rs7628207 chr3:49754970 T/C cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Intelligence (multi-trait analysis); TGCT cis rs61776719 0.875 rs4072980 chr1:38456106 G/A cg26398791 chr1:38455867 SF3A3 0.6 5.77 0.46 5.94e-8 Coronary artery disease; TGCT cis rs1552244 0.554 rs2272119 chr3:10049352 A/G cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs11690935 0.959 rs77280952 chr2:172620151 G/C cg13550731 chr2:172543902 DYNC1I2 -1.2 -12.28 -0.74 3.49e-23 Schizophrenia; TGCT cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg07220782 chr6:26987966 LOC100270746;C6orf41 0.52 5.83 0.46 4.51e-8 Autism spectrum disorder or schizophrenia; TGCT trans rs208520 0.690 rs851459 chr6:66813989 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.61 -0.69 4.11e-19 Exhaled nitric oxide output; TGCT cis rs10193935 0.901 rs6544536 chr2:42522042 G/A cg27598129 chr2:42591480 NA -0.35 -4.89 -0.4 3.09e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg05985448 chr10:134359359 INPP5A 0.24 5.13 0.42 1.1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs514406 0.861 rs12038438 chr1:53230581 A/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.98 -0.63 3.64e-15 Monocyte count; TGCT cis rs7617480 0.648 rs9864243 chr3:48982732 G/A cg05785598 chr3:49045655 WDR6 0.39 4.52 0.38 1.42e-5 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7586879 0.964 rs6545795 chr2:25116783 C/T cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs6088580 0.634 rs6142157 chr20:32984172 C/G cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs11786130 0.544 rs4733823 chr8:129014697 C/T cg00780520 chr8:128808554 PVT1 0.2 4.53 0.38 1.37e-5 Eosinophil counts;Sum eosinophil basophil counts; TGCT cis rs9329221 0.592 rs7832708 chr8:10190040 C/T cg27411982 chr8:10470053 RP1L1 0.21 4.7 0.39 6.72e-6 Neuroticism; TGCT cis rs7312933 0.533 rs11181499 chr12:42818761 A/G cg19980929 chr12:42632907 YAF2 0.42 5.91 0.47 3.05e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6964587 0.967 rs6973896 chr7:91778465 A/G cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.33e-6 Breast cancer; TGCT cis rs7666738 0.791 rs6828752 chr4:99063382 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10461617 0.535 rs7709874 chr5:56047451 C/T cg24531977 chr5:56204891 C5orf35 -0.46 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs4700695 0.543 rs37233 chr5:65222207 C/G cg21114390 chr5:65439923 SFRS12 0.7 4.89 0.4 3.03e-6 Facial morphology (factor 19); TGCT cis rs2464469 0.618 rs8024164 chr15:58205900 A/G cg12031962 chr15:58353849 ALDH1A2 0.34 4.67 0.39 7.86e-6 Barrett's esophagus or Esophageal adenocarcinoma; TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg10263370 chr3:44754102 ZNF502 -0.44 -5.23 -0.43 7.03e-7 Depressive symptoms; TGCT cis rs28595532 1.000 rs11098451 chr4:119717673 C/T cg11846333 chr4:119757529 SEC24D 0.81 4.75 0.39 5.62e-6 Cannabis dependence symptom count; TGCT cis rs597539 0.652 rs668576 chr11:68668208 A/G cg21963583 chr11:68658836 MRPL21 0.36 6.04 0.48 1.7e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12681287 0.640 rs7830480 chr8:87403137 T/C cg27223183 chr8:87520930 FAM82B 0.87 6.39 0.5 3e-9 Caudate activity during reward; TGCT cis rs4268898 0.735 rs12469585 chr2:24489054 A/T cg02683114 chr2:24398427 C2orf84 0.2 4.95 0.41 2.39e-6 Asthma; TGCT cis rs6460942 0.915 rs2192842 chr7:12315752 C/G cg06484146 chr7:12443880 VWDE -0.48 -4.82 -0.4 4.08e-6 Coronary artery disease; TGCT cis rs6558530 0.692 rs6558521 chr8:1700818 C/T cg09410841 chr8:1729607 CLN8 -0.68 -6.27 -0.49 5.45e-9 Systolic blood pressure; TGCT cis rs634534 0.562 rs642293 chr11:65730217 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.6 6.03 0.48 1.75e-8 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs78487399 0.808 rs6752448 chr2:43682596 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3806843 0.576 rs155363 chr5:140301543 A/G cg09824255 chr5:140014002 CD14 0.25 4.49 0.37 1.63e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg18538332 chr22:24372958 LOC391322 -0.99 -12.8 -0.75 2e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs739496 0.527 rs61440627 chr12:112318997 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs79149102 0.579 rs7342591 chr15:75306863 C/T cg09165964 chr15:75287851 SCAMP5 1.04 5.73 0.46 7.2e-8 Lung cancer; TGCT cis rs7659604 0.539 rs7660548 chr4:122730821 G/C cg19748678 chr4:122722346 EXOSC9 0.9 9.34 0.64 4.9e-16 Type 2 diabetes; TGCT cis rs7809950 0.817 rs2253833 chr7:107205669 A/G cg23024343 chr7:107201750 COG5 0.42 5.95 0.47 2.56e-8 Coronary artery disease; TGCT cis rs2795502 1.000 rs2142991 chr10:43341105 C/T cg20628663 chr10:43360327 NA -0.44 -6.23 -0.49 6.74e-9 Blood protein levels; TGCT cis rs9929218 0.954 rs72785165 chr16:68755635 T/A cg01251360 chr16:68772225 CDH1 0.29 4.8 0.4 4.46e-6 Colorectal cancer; TGCT cis rs3772130 0.540 rs11717089 chr3:121563271 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.59 5.43 0.44 2.8e-7 Cognitive performance; TGCT cis rs3749237 0.615 rs11130202 chr3:49566715 C/T cg03060546 chr3:49711283 APEH 0.75 8.65 0.61 2.25e-14 Resting heart rate; TGCT cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg05896524 chr21:47604654 C21orf56 0.43 4.62 0.38 9.37e-6 Testicular germ cell tumor; TGCT cis rs74233809 0.515 rs72841270 chr10:104642237 T/G cg05855489 chr10:104503620 C10orf26 0.72 5.42 0.44 2.99e-7 Birth weight; TGCT cis rs4665809 1.000 rs10182857 chr2:26344411 C/T cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs1005277 0.522 rs9417256 chr10:37976990 A/G cg25427524 chr10:38739819 LOC399744 -0.33 -6.48 -0.5 1.99e-9 Extrinsic epigenetic age acceleration; TGCT cis rs7953508 0.506 rs2053196 chr12:93962959 T/C cg18151635 chr12:93972918 NA -0.19 -4.53 -0.38 1.35e-5 Pubertal anthropometrics; TGCT cis rs2072499 0.966 rs2842857 chr1:156168736 T/C cg06970220 chr1:156163860 SLC25A44 0.73 6.46 0.5 2.13e-9 Testicular germ cell tumor; TGCT cis rs79349575 0.783 rs56046215 chr17:47008757 A/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs8177253 0.965 rs1525889 chr3:133490033 A/C cg01448562 chr3:133502909 NA -0.33 -6.8 -0.52 3.92e-10 Iron status biomarkers; TGCT cis rs12477438 0.520 rs12467504 chr2:99543208 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -4.83 -0.4 4e-6 Chronic sinus infection; TGCT cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg17054783 chr10:134559939 INPP5A 0.28 5.64 0.45 1.07e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs28595532 0.920 rs116098781 chr4:119771613 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs6459788 0.693 rs11981578 chr7:157250133 C/T cg03453431 chr7:157225567 NA -0.4 -6.01 -0.47 1.93e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs1372520 0.627 rs2737025 chr4:90719192 A/G cg01966878 chr4:90757139 SNCA -0.31 -4.84 -0.4 3.8e-6 Neuroticism; TGCT cis rs4642101 0.597 rs12638595 chr3:12819281 T/C cg05775895 chr3:12838266 CAND2 0.89 9.52 0.65 1.87e-16 QRS complex (12-leadsum); TGCT cis rs7666738 0.830 rs10031292 chr4:99056877 A/G cg05340658 chr4:99064831 C4orf37 0.51 5.69 0.45 8.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7085104 0.660 rs3781286 chr10:104595719 C/T cg05855489 chr10:104503620 C10orf26 0.54 4.94 0.41 2.47e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs9297145 0.715 rs62473008 chr7:98751541 A/G cg05967295 chr7:98741636 SMURF1 1.0 12.82 0.75 1.81e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs12762955 0.507 rs7095853 chr10:1040798 T/C cg18964960 chr10:1102726 WDR37 -0.68 -5.86 -0.47 3.86e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs7829975 0.501 rs74345345 chr8:8578435 C/G cg06636001 chr8:8085503 FLJ10661 -0.53 -4.44 -0.37 1.96e-5 Mood instability; TGCT cis rs6671200 1.000 rs259354 chr1:95718205 T/C cg03123541 chr1:95699097 RWDD3 -0.91 -6.4 -0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs10875746 0.669 rs10875770 chr12:48600520 A/G cg20731937 chr12:48336164 NA 0.58 4.52 0.38 1.44e-5 Longevity (90 years and older); TGCT cis rs4771122 0.697 rs1475220 chr13:28037448 G/C cg22138327 chr13:27999177 GTF3A -0.68 -5.35 -0.43 4.15e-7 Body mass index; TGCT cis rs769267 0.930 rs7254927 chr19:19404786 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs801193 0.935 rs2286683 chr7:66129843 G/A cg18876405 chr7:65276391 NA -0.34 -5.19 -0.42 8.37e-7 Aortic root size; TGCT cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg09549813 chr16:4587862 C16orf5 -0.28 -4.51 -0.38 1.5e-5 Schizophrenia; TGCT cis rs60154123 0.505 rs115881613 chr1:210040369 C/T cg23283495 chr1:209979779 IRF6 0.67 4.99 0.41 1.96e-6 Coronary artery disease; TGCT cis rs7819412 0.668 rs2409715 chr8:11010136 A/T cg21775007 chr8:11205619 TDH -0.62 -5.74 -0.46 6.75e-8 Triglycerides; TGCT cis rs6831352 0.879 rs67311928 chr4:100048999 A/G cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg03188948 chr7:1209495 NA 0.41 5.42 0.44 2.98e-7 Longevity;Endometriosis; TGCT cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg00149659 chr3:10157352 C3orf10 0.97 5.98 0.47 2.19e-8 Alzheimer's disease; TGCT cis rs854765 0.663 rs16960744 chr17:17755259 A/G cg04398451 chr17:18023971 MYO15A 0.29 4.52 0.38 1.44e-5 Total body bone mineral density; TGCT cis rs2282802 0.685 rs2436391 chr5:139557385 C/T cg01081189 chr5:139537190 NA -0.3 -5.37 -0.43 3.82e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs11864453 0.713 rs3764312 chr16:72125733 A/C cg14768367 chr16:72042858 DHODH 0.5 4.8 0.4 4.5e-6 Fibrinogen levels; TGCT cis rs3020736 0.500 rs764481 chr22:42518426 G/A cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs1372520 1.000 rs1372520 chr4:90757505 T/C cg26578617 chr4:90757533 SNCA -0.55 -4.71 -0.39 6.51e-6 Neuroticism; TGCT cis rs9926296 0.533 rs12102297 chr16:89812762 C/A cg26513180 chr16:89883248 FANCA 1.07 14.67 0.8 7.16e-29 Vitiligo; TGCT cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg05025164 chr4:1340916 KIAA1530 -0.55 -4.75 -0.39 5.41e-6 Obesity-related traits; TGCT cis rs61867294 0.501 rs7076627 chr10:106714848 A/G cg08000847 chr10:105880925 C10orf78 0.47 4.45 0.37 1.91e-5 Schizophrenia; TGCT cis rs12693043 0.790 rs17257938 chr2:175407780 C/T cg11778734 chr2:175439522 WIPF1 -0.37 -4.9 -0.4 2.94e-6 Urate levels (BMI interaction); TGCT cis rs9560113 0.597 rs947170 chr13:112241062 G/A cg10483660 chr13:112241077 NA -0.34 -5.34 -0.43 4.18e-7 Menarche (age at onset); TGCT cis rs6681544 0.760 rs11163394 chr1:82398752 G/A cg04226724 chr1:82268649 LPHN2 0.48 4.97 0.41 2.19e-6 Metabolite levels (X-11787); TGCT cis rs7192750 0.517 rs152827 chr16:72126753 C/G cg06353428 chr16:71660113 MARVELD3 1.12 5.56 0.45 1.59e-7 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9291683 0.610 rs993173 chr4:10323935 T/C cg11266682 chr4:10021025 SLC2A9 -0.51 -6.04 -0.48 1.64e-8 Bone mineral density; TGCT cis rs9677476 0.542 rs10179264 chr2:232050603 G/C cg07929768 chr2:232055508 NA 0.32 5.05 0.41 1.53e-6 Food antigen IgG levels; TGCT cis rs67478160 0.679 rs8011109 chr14:104279974 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs9640161 0.789 rs28439010 chr7:150046276 C/T cg10018233 chr7:150070692 REPIN1 0.31 4.55 0.38 1.25e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg11644478 chr21:40555479 PSMG1 -0.54 -4.89 -0.4 3.02e-6 Menarche (age at onset); TGCT cis rs11644362 0.966 rs976011 chr16:12992910 C/T cg06890432 chr16:12997467 SHISA9 -0.61 -6.77 -0.52 4.49e-10 Positive affect;Subjective well-being; TGCT cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg13695892 chr22:41940480 POLR3H 1.0 7.98 0.58 8.2e-13 Vitiligo; TGCT cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg17054783 chr10:134559939 INPP5A 0.25 4.89 0.4 3e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6074578 0.679 rs6055460 chr20:139362 G/A cg16931068 chr20:139680 DEFB127 -0.28 -4.83 -0.4 3.89e-6 Hirschsprung disease; TGCT cis rs3540 0.960 rs12440447 chr15:91022694 C/G cg22089800 chr15:90895588 ZNF774 0.74 6.91 0.53 2.27e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs4555082 0.750 rs2816650 chr14:105708343 C/T cg01266790 chr14:105781312 PACS2 0.55 4.49 0.37 1.58e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs11190604 1.000 rs2495734 chr10:102338686 G/A cg23241863 chr10:102295624 HIF1AN 0.67 4.9 0.4 2.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs8111998 0.625 rs7255845 chr19:22766051 C/T cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs2075371 0.501 rs1421469 chr7:134028260 C/G cg11752832 chr7:134001865 SLC35B4 0.59 5.08 0.42 1.35e-6 Mean platelet volume; TGCT cis rs3820068 0.705 rs4646022 chr1:15839112 G/A cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs875971 1.000 rs35149210 chr7:65929925 T/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs6582630 0.519 rs4002440 chr12:38485012 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs9733 0.519 rs7529194 chr1:150622620 A/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.91 0.4 2.82e-6 Tonsillectomy; TGCT cis rs79349575 0.691 rs11079847 chr17:47037024 A/T cg26022315 chr17:47021804 SNF8 -0.49 -4.5 -0.38 1.51e-5 Type 2 diabetes; TGCT cis rs11864453 0.713 rs8051882 chr16:72142072 A/G cg14768367 chr16:72042858 DHODH -0.5 -4.92 -0.4 2.64e-6 Fibrinogen levels; TGCT trans rs877282 1.000 rs11253362 chr10:770979 G/T cg22713356 chr15:30763199 NA 1.2 10.69 0.69 2.63e-19 Uric acid levels; TGCT cis rs2456568 0.867 rs1827931 chr11:93663170 T/C cg16099599 chr11:93583650 C11orf90 -0.4 -4.72 -0.39 6.23e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1008375 1.000 rs6449319 chr4:17640283 T/A cg10189774 chr4:17578691 LAP3 0.65 5.7 0.46 8.42e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11148252 0.574 rs73186430 chr13:53232891 T/C cg02158880 chr13:53174818 NA 0.41 4.9 0.4 2.96e-6 Lewy body disease; TGCT cis rs4319547 0.661 rs7398014 chr12:122943980 T/C cg05707623 chr12:122985044 ZCCHC8 -0.7 -5.65 -0.45 1.05e-7 Body mass index; TGCT cis rs644799 0.932 rs10831447 chr11:95663017 C/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.83 -5.83 -0.46 4.46e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10504229 1.000 rs10504229 chr8:58196495 A/G cg08280861 chr8:58055591 NA 0.36 4.6 0.38 1.05e-5 Developmental language disorder (linguistic errors); TGCT trans rs8073060 0.572 rs1634683 chr17:33941560 G/C cg19694781 chr19:47549865 TMEM160 -0.59 -12.7 -0.75 3.37e-24 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1055129 0.560 rs56248937 chr17:73915153 T/A cg08125733 chr17:73851984 WBP2 0.57 5.25 0.43 6.4e-7 White matter hyperintensity burden; TGCT trans rs916888 0.821 rs70602 chr17:44859715 T/C cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8067545 1.000 rs4925067 chr17:19921222 C/G cg13482628 chr17:19912719 NA 0.54 4.74 0.39 5.86e-6 Schizophrenia; TGCT cis rs1371867 0.875 rs1788174 chr8:101330957 C/G cg00191853 chr8:101177733 SPAG1 0.23 4.57 0.38 1.18e-5 Atrioventricular conduction; TGCT cis rs7201929 1.000 rs7499878 chr16:28868464 C/T cg09754948 chr16:28834200 ATXN2L -0.63 -4.94 -0.41 2.42e-6 QT interval; TGCT cis rs7772486 0.754 rs9497419 chr6:146142609 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.72 0.39 6.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11651000 0.625 rs4794063 chr17:45804494 C/T cg06532163 chr17:45867833 NA 0.32 5.14 0.42 1.04e-6 IgG glycosylation; TGCT cis rs2456568 0.867 rs4753111 chr11:93658410 A/G cg16099599 chr11:93583650 C11orf90 -0.41 -4.78 -0.39 4.87e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs34014631 1.000 rs41291490 chr10:103590737 T/A cg22630918 chr10:102748988 C10orf2 0.43 4.83 0.4 3.98e-6 Coronary artery calcification; TGCT cis rs1878931 0.567 rs7196196 chr16:3411855 C/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.97 11.5 0.72 2.84e-21 Body mass index (adult); TGCT cis rs9532580 0.620 rs2701859 chr13:41141232 T/C cg21288729 chr13:41239152 FOXO1 0.89 7.47 0.56 1.24e-11 Mean corpuscular hemoglobin; TGCT trans rs7698623 0.717 rs4693193 chr4:88797992 T/C cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs7824557 0.585 rs2572385 chr8:11208903 G/A cg21775007 chr8:11205619 TDH 0.75 7.15 0.54 6.5e-11 Retinal vascular caliber; TGCT cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg18252515 chr7:66147081 NA -1.21 -7.89 -0.58 1.36e-12 Diabetic kidney disease; TGCT cis rs2073300 1.000 rs6132621 chr20:23442180 C/T cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs2422052 0.519 rs11123458 chr2:118633602 A/G cg05295388 chr2:118594304 NA -0.28 -4.88 -0.4 3.22e-6 Mosquito bite size; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg25703541 chr22:24373054 LOC391322 -0.81 -8.47 -0.61 5.88e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10206020 0.921 rs2280127 chr2:1546531 C/T cg12573674 chr2:1569213 NA -0.49 -4.93 -0.41 2.54e-6 IgG glycosylation; TGCT cis rs6427419 1.000 rs6427419 chr1:158058109 C/A cg07184316 chr1:157669111 FCRL3 0.25 4.62 0.38 9.6e-6 Obesity-related traits; TGCT cis rs4919694 1.000 rs4917988 chr10:104752830 T/G cg04362960 chr10:104952993 NT5C2 1.07 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg10117171 chr1:25599238 RHD -0.33 -5.46 -0.44 2.44e-7 Erythrocyte sedimentation rate; TGCT cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg18735214 chr6:43276756 CRIP3 -0.56 -4.88 -0.4 3.24e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4237845 0.761 rs11172378 chr12:58298161 C/T cg23860436 chr12:58378763 NA 0.34 4.97 0.41 2.18e-6 Intelligence (multi-trait analysis); TGCT cis rs9325144 0.723 rs10161183 chr12:39182087 T/C cg10518543 chr12:38710700 ALG10B -0.5 -4.65 -0.39 8.28e-6 Morning vs. evening chronotype; TGCT cis rs4891159 0.790 rs35516239 chr18:74129942 C/T cg24786174 chr18:74118243 ZNF516 -0.59 -8.98 -0.63 3.73e-15 Longevity; TGCT cis rs16867321 0.950 rs2887180 chr2:181449305 C/A cg23363182 chr2:181467187 NA -0.39 -5.47 -0.44 2.38e-7 Obesity; TGCT cis rs524281 0.861 rs471484 chr11:65955144 A/G cg00563793 chr11:65837595 PACS1 0.55 5.01 0.41 1.84e-6 Electroencephalogram traits; TGCT cis rs11190604 1.000 rs1054399 chr10:102312565 C/T cg16342193 chr10:102329863 NA -0.39 -4.95 -0.41 2.36e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7639513 0.767 rs7648488 chr3:12708946 T/C cg23032965 chr3:12705835 RAF1 0.77 8.55 0.61 3.81e-14 Itch intensity from mosquito bite; TGCT cis rs5769707 0.967 rs4524218 chr22:50018639 G/A cg20744362 chr22:50050164 C22orf34 0.27 4.47 0.37 1.77e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10769025 0.511 rs7930973 chr11:44181028 A/G cg17479956 chr11:44115929 EXT2 0.19 4.47 0.37 1.73e-5 Gout; TGCT cis rs56104184 0.668 rs73063523 chr19:49408943 T/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4566357 0.615 rs3769643 chr2:227917270 T/C cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs7394190 0.748 rs3088070 chr10:75530013 C/T cg07699608 chr10:75541558 CHCHD1 0.8 5.21 0.42 7.72e-7 Incident atrial fibrillation; TGCT cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs9916302 0.851 rs12936646 chr17:37647450 A/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs12497850 0.931 rs13315711 chr3:48986399 A/T cg06212747 chr3:49208901 KLHDC8B 0.6 5.43 0.44 2.82e-7 Parkinson's disease; TGCT cis rs34526934 0.566 rs62624470 chr2:177040907 C/T cg26754761 chr2:177040938 NA -0.3 -5.6 -0.45 1.33e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs11792861 0.926 rs59904140 chr9:111910051 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.51 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs13217239 0.646 rs12201393 chr6:26975690 C/A cg02458000 chr6:26745757 NA 0.5 4.61 0.38 9.84e-6 Schizophrenia; TGCT cis rs6570726 0.791 rs9322029 chr6:145906683 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT trans rs10506458 0.915 rs12424908 chr12:63402364 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs7552404 0.960 rs4949877 chr1:76201668 C/G cg10523679 chr1:76189770 ACADM 0.9 9.71 0.66 6.5e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs548987 0.507 rs35875210 chr6:25827484 A/G cg03517284 chr6:25882590 NA -0.55 -4.44 -0.37 1.93e-5 Homocysteine levels; TGCT cis rs9914544 0.545 rs4290526 chr17:18772967 T/C cg26378065 chr17:18585709 ZNF286B 0.51 4.45 0.37 1.88e-5 Educational attainment (years of education); TGCT cis rs7539409 0.604 rs910183 chr1:84297285 A/G cg10977910 chr1:84465055 TTLL7 0.96 5.87 0.47 3.76e-8 Alzheimer's disease; TGCT cis rs7605378 1.000 rs796363 chr2:200693668 T/C cg23649088 chr2:200775458 C2orf69 0.35 5.83 0.46 4.53e-8 Osteoporosis; TGCT cis rs617219 0.737 rs13158309 chr5:78463395 C/T cg05890484 chr5:78407552 BHMT -0.36 -4.96 -0.41 2.32e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs12368653 0.544 rs11172304 chr12:58097862 T/C cg12615879 chr12:58013172 SLC26A10 0.45 5.28 0.43 5.47e-7 Multiple sclerosis; TGCT cis rs7302981 0.967 rs12815871 chr12:50550948 G/A cg23855989 chr12:50355821 AQP5 0.3 4.5 0.38 1.52e-5 Systolic blood pressure; TGCT cis rs1801251 1.000 rs7578299 chr2:233573469 G/T cg25237894 chr2:233734115 C2orf82 0.31 5.52 0.44 1.92e-7 Coronary artery disease; TGCT cis rs597539 0.652 rs668576 chr11:68668208 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.3 0.6 1.49e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs35865860 chr4:98968822 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3820068 0.603 rs927207 chr1:15990552 A/G cg05660106 chr1:15850417 CASP9 0.79 7.22 0.54 4.55e-11 Systolic blood pressure; TGCT cis rs617219 0.710 rs2255913 chr5:78562399 G/C cg05890484 chr5:78407552 BHMT 0.34 4.63 0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6582630 0.502 rs1607867 chr12:38385463 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.72e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg10862848 chr6:42927986 GNMT -0.39 -4.7 -0.39 6.86e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6988636 1.000 rs16898095 chr8:124193523 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs6940638 1.000 rs12204280 chr6:27033104 T/C cg16898833 chr6:26189333 HIST1H4D 0.71 5.34 0.43 4.2e-7 Intelligence (multi-trait analysis); TGCT cis rs4589502 0.502 rs2169460 chr15:67197240 A/G cg12317470 chr15:67143691 NA -0.52 -5.12 -0.42 1.12e-6 Lung cancer (smoking interaction); TGCT cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg07061783 chr6:25882402 NA 0.72 7.17 0.54 5.98e-11 Blood metabolite levels; TGCT cis rs7088591 1.000 rs80032439 chr10:59730438 A/T cg07264682 chr10:60082823 NA 0.39 4.65 0.39 8.44e-6 Blood pressure; TGCT cis rs2153535 0.541 rs6905934 chr6:8440043 C/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs7617773 0.780 rs35297486 chr3:48378147 T/A cg11946769 chr3:48343235 NME6 0.82 6.99 0.53 1.49e-10 Coronary artery disease; TGCT cis rs7552167 1.000 rs59960858 chr1:24519437 C/A cg01960748 chr1:24522592 NA 0.6 6.44 0.5 2.42e-9 Psoriasis vulgaris; TGCT cis rs7914558 1.000 rs11191542 chr10:104824324 T/A cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.37e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3733585 0.631 rs7699671 chr4:10125874 C/T cg00071950 chr4:10020882 SLC2A9 -0.49 -5.1 -0.42 1.26e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8102137 0.665 rs3218069 chr19:30313576 C/T cg09247459 chr19:30364939 NA 0.31 4.7 0.39 6.85e-6 Bladder cancer; TGCT cis rs3733585 0.673 rs6836706 chr4:9964251 T/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7267979 1.000 rs2258617 chr20:25274318 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8177253 1.000 rs3811647 chr3:133484029 G/A cg11941060 chr3:133502564 NA -0.29 -6.12 -0.48 1.12e-8 Iron status biomarkers; TGCT cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs10832963 1.000 rs4757676 chr11:18640477 C/T cg20219074 chr11:18656078 SPTY2D1 1.0 9.93 0.67 1.85e-17 Breast cancer; TGCT cis rs12477438 0.765 rs7591992 chr2:99668954 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs9308731 1.000 rs2241845 chr2:111879100 A/G cg04202892 chr2:111875749 ACOXL 0.43 4.68 0.39 7.48e-6 Chronic lymphocytic leukemia; TGCT cis rs7714584 1.000 rs73284141 chr5:150266086 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs6725041 0.819 rs939226 chr2:213088846 A/G cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs981844 0.778 rs55895613 chr4:154638121 G/T cg14289246 chr4:154710475 SFRP2 0.98 7.59 0.56 6.55e-12 Response to statins (LDL cholesterol change); TGCT cis rs1372520 0.808 rs1372518 chr4:90757294 A/C cg01966878 chr4:90757139 SNCA -0.3 -4.59 -0.38 1.09e-5 Neuroticism; TGCT trans rs877282 0.898 rs11253347 chr10:765769 A/G cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs4727027 0.933 rs10238826 chr7:148830888 A/G cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs8014204 1.000 rs8014374 chr14:75322914 G/A cg06637938 chr14:75390232 RPS6KL1 -0.74 -7.11 -0.54 8e-11 Caffeine consumption; TGCT cis rs2197308 0.765 rs11182992 chr12:37935572 G/C cg13010199 chr12:38710504 ALG10B 0.66 5.33 0.43 4.41e-7 Morning vs. evening chronotype; TGCT cis rs651907 0.557 rs13077925 chr3:101488181 T/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.5 4.61 0.38 9.98e-6 Colorectal cancer; TGCT cis rs9902453 1.000 rs9890886 chr17:28391076 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs2282802 0.685 rs2337138 chr5:139691664 A/C cg01081189 chr5:139537190 NA 0.27 5.01 0.41 1.87e-6 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs62380364 0.602 rs610217 chr5:88065263 G/A cg24804195 chr5:87968844 LOC645323 -0.57 -5.46 -0.44 2.54e-7 Intelligence (multi-trait analysis); TGCT cis rs10510102 0.872 rs11200277 chr10:123703810 A/G cg23691251 chr10:123688108 ATE1 -0.62 -4.66 -0.39 8.16e-6 Breast cancer; TGCT cis rs981844 0.583 rs2289318 chr4:154633734 G/C cg14289246 chr4:154710475 SFRP2 0.97 7.51 0.56 1.03e-11 Response to statins (LDL cholesterol change); TGCT cis rs2153535 0.580 rs6920779 chr6:8437624 C/T cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs546131 0.928 rs516228 chr11:34838823 C/T cg06937548 chr11:34938143 PDHX;APIP 0.57 5.11 0.42 1.2e-6 Lung disease severity in cystic fibrosis; TGCT cis rs35883536 0.647 rs7524322 chr1:101047730 C/G cg10298815 chr1:101004474 GPR88 0.24 4.47 0.37 1.73e-5 Monocyte count; TGCT cis rs17826219 0.500 rs9891256 chr17:29072692 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs1691799 0.899 rs1168325 chr12:66728234 C/G cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.77e-9 White blood cell count (basophil); TGCT cis rs4886920 0.563 rs8040813 chr15:78073289 A/G cg03457338 chr15:78040120 NA -0.18 -4.57 -0.38 1.16e-5 Neuroticism; TGCT cis rs9486719 0.741 rs976356 chr6:96849437 T/A cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs9467711 0.516 rs1165163 chr6:25863487 G/C cg03264133 chr6:25882463 NA -0.67 -4.47 -0.37 1.76e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs34517613 0.589 rs12937920 chr17:26590657 C/T cg08652245 chr17:26833078 NA 0.33 4.44 0.37 1.98e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9926296 0.533 rs12102290 chr16:89812617 C/T cg04287289 chr16:89883240 FANCA 0.92 11.34 0.71 6.88e-21 Vitiligo; TGCT cis rs3125734 0.633 rs10740068 chr10:63982254 A/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.52 -0.38 1.4e-5 Rheumatoid arthritis; TGCT cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg22166914 chr1:53195759 ZYG11B -0.46 -8.45 -0.6 6.74e-14 Monocyte count; TGCT cis rs603424 0.593 rs3853519 chr10:102085327 C/T cg22671421 chr10:102507979 PAX2 -0.54 -4.61 -0.38 9.72e-6 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs1801251 1.000 rs283471 chr2:233656627 G/A cg08000102 chr2:233561755 GIGYF2 0.62 6.15 0.48 9.79e-9 Coronary artery disease; TGCT cis rs6542838 0.583 rs7565819 chr2:99519265 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.64 -0.38 8.77e-6 Fear of minor pain; TGCT cis rs597539 0.652 rs602805 chr11:68662076 A/T cg21862992 chr11:68658383 NA 0.47 6.58 0.51 1.19e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13191362 0.935 rs67889271 chr6:163045753 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.92 7.24 0.55 4.11e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1801251 1.000 rs12478564 chr2:233598340 C/T cg08000102 chr2:233561755 GIGYF2 0.64 6.53 0.51 1.53e-9 Coronary artery disease; TGCT cis rs3935685 0.934 rs11072664 chr15:77999859 C/G cg03457338 chr15:78040120 NA -0.22 -5.17 -0.42 9.25e-7 Intelligence (multi-trait analysis); TGCT cis rs3096299 0.719 rs12934708 chr16:89523790 C/T cg06640241 chr16:89574553 SPG7 0.76 8.5 0.61 5.12e-14 Multiple myeloma (IgH translocation); TGCT cis rs4664308 0.870 rs2198918 chr2:161015052 C/T cg03641300 chr2:160917029 PLA2R1 -0.27 -6.89 -0.53 2.48e-10 Idiopathic membranous nephropathy; TGCT trans rs9951602 0.512 rs6506868 chr18:76642559 C/G cg02800362 chr5:177631904 HNRNPAB 1.12 12.7 0.75 3.48e-24 Obesity-related traits; TGCT cis rs6430585 0.528 rs7606267 chr2:136668123 T/C cg07169764 chr2:136633963 MCM6 1.25 12.45 0.75 1.36e-23 Corneal structure; TGCT cis rs11874712 0.545 rs9955008 chr18:43658888 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 -0.48 -4.68 -0.39 7.25e-6 Migraine - clinic-based; TGCT cis rs2882877 0.648 rs66883355 chr2:190397021 G/A cg10752008 chr2:190445175 SLC40A1 0.62 4.53 0.38 1.39e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs12950390 0.853 rs67441169 chr17:45854462 T/G cg24803719 chr17:45855879 NA -0.5 -5.05 -0.41 1.51e-6 IgG glycosylation; TGCT cis rs4141404 0.748 rs2232170 chr22:31537122 A/G cg01546248 chr22:31477006 SMTN -0.63 -4.74 -0.39 5.71e-6 Paclitaxel-induced neuropathy; TGCT cis rs9611519 0.589 rs8138917 chr22:41412425 T/C cg03806693 chr22:41940476 POLR3H -0.65 -6.15 -0.48 9.75e-9 Neuroticism; TGCT cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg18252515 chr7:66147081 NA -1.21 -7.69 -0.57 3.87e-12 Diabetic kidney disease; TGCT cis rs10751667 0.580 rs10751664 chr11:927077 T/G cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs6089584 0.888 rs6061973 chr20:60610870 C/T cg06108461 chr20:60628389 TAF4 -0.69 -10.56 -0.69 5.46e-19 Body mass index; TGCT cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg10802521 chr3:52805072 NEK4 0.72 9.11 0.63 1.82e-15 Bipolar disorder; TGCT cis rs651907 0.557 rs34947019 chr3:101532235 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.87 0.4 3.32e-6 Colorectal cancer; TGCT cis rs7666738 0.830 rs28818180 chr4:98953625 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg25811766 chr13:21894605 NA 0.26 5.19 0.42 8.46e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs921968 0.643 rs6708683 chr2:219504503 G/A cg02176678 chr2:219576539 TTLL4 0.38 5.47 0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs2742417 1.000 rs1609554 chr3:45735192 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7666738 0.830 rs13148363 chr4:98847498 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.23 0.54 4.35e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs56235845 0.694 rs6860069 chr5:176755841 C/T cg17509989 chr5:176798049 RGS14 0.56 7.47 0.56 1.23e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs80282103 0.618 rs11819230 chr10:1128812 A/G cg08668510 chr10:1095578 IDI1 1.07 5.31 0.43 5e-7 Glomerular filtration rate (creatinine); TGCT cis rs36051895 0.664 rs10115172 chr9:5098549 C/T cg02405213 chr9:5042618 JAK2 -0.71 -9.43 -0.65 3.07e-16 Pediatric autoimmune diseases; TGCT cis rs2404602 0.684 rs965818 chr15:76866785 T/C cg23625390 chr15:77176239 SCAPER -0.37 -4.67 -0.39 7.71e-6 Blood metabolite levels; TGCT cis rs644799 0.544 rs1254935 chr11:95631470 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.53 5.32 0.43 4.67e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7917772 0.503 rs6584510 chr10:104299868 T/G cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7572733 0.576 rs1368989 chr2:198937082 T/C cg00792783 chr2:198669748 PLCL1 0.59 5.19 0.42 8.41e-7 Dermatomyositis; TGCT cis rs61990749 0.544 rs2544566 chr14:78181738 C/G cg23188588 chr14:78226832 SNW1;C14orf178 0.66 4.65 0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs11231629 1 rs11231629 chr11:63648573 C/T cg04850017 chr11:63683019 RCOR2 0.35 5.63 0.45 1.17e-7 Schizophrenia; TGCT cis rs4851254 0.660 rs77023845 chr2:100712346 G/A cg04109781 chr2:100722022 AFF3 0.47 4.63 0.38 8.9e-6 Intelligence (multi-trait analysis); TGCT cis rs1801251 1.000 rs36007169 chr2:233621834 A/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs11605924 0.901 rs11038672 chr11:45846498 C/G ch.11.939596F chr11:45881766 CRY2 -0.36 -4.47 -0.37 1.73e-5 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs7582180 0.630 rs13021801 chr2:100935129 C/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.95e-6 Intelligence (multi-trait analysis); TGCT cis rs796364 0.616 rs2030653 chr2:200677625 C/T cg17644776 chr2:200775616 C2orf69 0.34 4.84 0.4 3.76e-6 Schizophrenia; TGCT cis rs7226408 0.857 rs56217642 chr18:34687844 G/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6671200 0.607 rs3753872 chr1:95699184 T/G cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs7772486 0.686 rs1292337 chr6:145967807 A/G cg23711669 chr6:146136114 FBXO30 -0.83 -8.98 -0.63 3.75e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7635838 0.596 rs13353463 chr3:11260221 T/C cg00170343 chr3:11313890 ATG7 0.59 5.61 0.45 1.26e-7 HDL cholesterol; TGCT cis rs9303401 0.614 rs34550282 chr17:57092788 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.82 0.46 4.69e-8 Cognitive test performance; TGCT cis rs3617 0.625 rs2336558 chr3:52886240 C/T cg11645453 chr3:52864694 ITIH4 -0.3 -5.91 -0.47 3.03e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4927850 0.957 rs4927851 chr3:195751853 A/G cg22891161 chr3:195456627 MUC20 -0.23 -5.38 -0.44 3.53e-7 Pancreatic cancer; TGCT cis rs739496 0.615 rs634389 chr12:112164715 C/G cg10833066 chr12:111807467 FAM109A 0.34 4.81 0.4 4.27e-6 Platelet count; TGCT cis rs4722166 0.630 rs6461667 chr7:22796743 A/G cg26061582 chr7:22766209 IL6 0.53 6.9 0.53 2.31e-10 Lung cancer; TGCT cis rs2197308 0.667 rs61920838 chr12:37856814 T/C cg26384229 chr12:38710491 ALG10B -0.67 -6.04 -0.48 1.63e-8 Morning vs. evening chronotype; TGCT cis rs1799949 0.965 rs8071278 chr17:41193910 A/T cg05368731 chr17:41323189 NBR1 0.9 8.79 0.62 1.03e-14 Menopause (age at onset); TGCT trans rs1005277 0.541 rs2263163 chr10:38389887 G/A cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs7172809 0.897 rs16968893 chr15:77825082 A/G cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs9914544 0.505 rs59633160 chr17:18761396 C/T cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs514406 0.825 rs3863643 chr1:53224577 C/T cg25767906 chr1:53392781 SCP2 0.48 5.56 0.45 1.57e-7 Monocyte count; TGCT cis rs514406 0.861 rs505444 chr1:53251860 C/T cg16325326 chr1:53192061 ZYG11B 0.71 8.94 0.63 4.44e-15 Monocyte count; TGCT cis rs12135062 0.851 rs2651925 chr1:3101863 C/G cg00254258 chr1:3105189 PRDM16 0.35 5.85 0.47 4.02e-8 Migraine; TGCT cis rs6912958 0.712 rs2787927 chr6:88412786 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.51 -4.88 -0.4 3.2e-6 Monocyte percentage of white cells; TGCT cis rs2204008 0.546 rs11519978 chr12:37998170 C/T cg26384229 chr12:38710491 ALG10B 0.87 7.79 0.57 2.32e-12 Bladder cancer; TGCT cis rs782590 0.967 rs4672054 chr2:55773093 C/A cg03859395 chr2:55845619 SMEK2 0.91 11.32 0.71 7.6e-21 Metabolic syndrome; TGCT cis rs1050631 1.000 rs1789550 chr18:33699553 C/T cg25426722 chr18:33708991 SLC39A6;ELP2 -0.56 -4.68 -0.39 7.3e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs208520 0.754 rs851592 chr6:66875175 G/T cg07460842 chr6:66804631 NA -0.91 -9.43 -0.65 2.99e-16 Exhaled nitric oxide output; TGCT cis rs2282802 0.651 rs13353827 chr5:139654537 T/C cg01081189 chr5:139537190 NA 0.28 5.15 0.42 9.75e-7 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs56331118 chr4:119767054 G/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs1801251 0.963 rs283481 chr2:233648091 A/G cg25237894 chr2:233734115 C2orf82 0.28 4.82 0.4 4.05e-6 Coronary artery disease; TGCT cis rs950169 0.922 rs11633075 chr15:85113972 C/A cg17173187 chr15:85201210 NMB 0.47 4.93 0.4 2.62e-6 Schizophrenia; TGCT cis rs2070488 0.965 rs13079145 chr3:38517992 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 9.05 0.63 2.52e-15 Electrocardiographic conduction measures; TGCT cis rs9329289 0.926 rs9329290 chr10:2542751 G/T cg15501526 chr10:2543763 NA 0.41 5.15 0.42 9.91e-7 Age-related hearing impairment; TGCT cis rs1729951 0.575 rs35289288 chr3:136680568 C/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs6933660 0.760 rs1825368 chr6:151775259 C/A cg10883421 chr6:151773342 RMND1;C6orf211 0.72 7.39 0.55 1.87e-11 Menarche (age at onset); TGCT cis rs7772486 0.558 rs62435775 chr6:146136415 G/C cg23711669 chr6:146136114 FBXO30 0.73 6.75 0.52 5.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg01727686 chr11:63997306 NUDT22;DNAJC4 0.22 4.71 0.39 6.44e-6 Platelet count; TGCT cis rs8072100 0.840 rs9895746 chr17:45479099 C/A cg08085267 chr17:45401833 C17orf57 -0.45 -5.08 -0.42 1.33e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs11249608 0.548 rs2132671 chr5:178457434 A/G cg23951258 chr5:178450506 ZNF879 -0.46 -4.66 -0.39 7.95e-6 Pubertal anthropometrics; TGCT cis rs7772486 0.875 rs2814869 chr6:146315509 G/A cg23711669 chr6:146136114 FBXO30 0.87 9.39 0.64 3.74e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs3947 1.000 rs4839 chr8:11701933 A/G cg02840367 chr8:11660030 FDFT1 0.86 5.99 0.47 2.07e-8 Blood protein levels; TGCT cis rs3806843 1.000 rs6898906 chr5:140169299 C/G cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs12210905 0.688 rs72843191 chr6:27383301 G/C cg08851530 chr6:28072375 NA 1.34 6.07 0.48 1.44e-8 Hip circumference adjusted for BMI; TGCT cis rs778371 0.723 rs1078323 chr2:233681512 T/G cg08000102 chr2:233561755 GIGYF2 -0.64 -7.23 -0.54 4.36e-11 Schizophrenia; TGCT cis rs782590 0.774 rs782629 chr2:55900283 C/T cg18811423 chr2:55921094 PNPT1 -0.62 -6.51 -0.5 1.67e-9 Metabolic syndrome; TGCT cis rs769267 0.930 rs2301784 chr19:19390749 G/A cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs6430585 0.528 rs309122 chr2:136761853 A/G cg07169764 chr2:136633963 MCM6 1.19 11.39 0.72 5.11e-21 Corneal structure; TGCT cis rs1568079 0.516 rs2361382 chr10:125220299 C/G cg14250450 chr10:124578544 NA -0.34 -4.71 -0.39 6.57e-6 Body mass index; TGCT cis rs17011478 0.744 rs17011523 chr2:75830612 T/C cg04669895 chr2:74941807 NA -0.54 -4.9 -0.4 2.88e-6 Obesity-related traits; TGCT cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg21644426 chr2:191273491 MFSD6 0.62 6.15 0.48 9.57e-9 Pulse pressure; TGCT cis rs4372836 0.964 rs17007191 chr2:28932502 C/T cg09522027 chr2:28974177 PPP1CB 0.58 4.92 0.4 2.67e-6 Body mass index; TGCT trans rs877282 0.853 rs11595507 chr10:756703 C/T cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs9393777 0.557 rs6933999 chr6:27074929 G/A cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.58 -5.73 -0.46 7.03e-8 Intelligence (multi-trait analysis); TGCT cis rs9914988 0.943 rs12951232 chr17:27132638 G/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs57506017 0.585 rs5011438 chr7:12268798 C/T cg07541786 chr7:12610355 SCIN 0.45 4.58 0.38 1.12e-5 Neuroticism; TGCT cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg17971929 chr21:40555470 PSMG1 -0.71 -6.5 -0.5 1.79e-9 Cognitive function; TGCT cis rs6725041 0.792 rs1521643 chr2:213091417 A/G cg16329650 chr2:213403929 ERBB4 -0.53 -4.58 -0.38 1.12e-5 QT interval (ambient particulate matter interaction); TGCT cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg00786635 chr1:25594202 NA 0.54 5.78 0.46 5.67e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs4727027 0.870 rs1534196 chr7:148790591 G/A cg23583168 chr7:148888333 NA -0.7 -8.85 -0.62 7.39e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs67311347 1.000 rs12638199 chr3:40475285 A/G cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs5771225 0.563 rs738334 chr22:50688235 T/C cg16473166 chr22:50639996 SELO 0.72 5.92 0.47 2.92e-8 Late-onset Alzheimer's disease; TGCT cis rs9902453 0.765 rs9890747 chr17:28007442 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.27 0.6 1.73e-13 Coffee consumption (cups per day); TGCT cis rs9942416 0.517 rs116509898 chr5:74994361 C/T cg19683494 chr5:74908142 NA 0.59 6.26 0.49 5.62e-9 Age-related disease endophenotypes; TGCT cis rs6840360 0.593 rs1366907 chr4:152682749 T/C cg17479576 chr4:152424074 FAM160A1 -0.52 -5.16 -0.42 9.49e-7 Intelligence (multi-trait analysis); TGCT cis rs1997103 0.954 rs2177807 chr7:55391002 G/T cg17469321 chr7:55412551 NA -0.54 -6.45 -0.5 2.26e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6088580 0.634 rs6088471 chr20:32932643 C/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.9 -0.4 2.97e-6 Glomerular filtration rate (creatinine); TGCT cis rs2832191 0.791 rs2832179 chr21:30480366 C/T cg08807101 chr21:30365312 RNF160 -0.66 -6.19 -0.49 8.16e-9 Dental caries; TGCT cis rs992157 0.798 rs7587220 chr2:219160864 C/A cg00012203 chr2:219082015 ARPC2 -0.82 -8.11 -0.59 4.07e-13 Colorectal cancer; TGCT cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9894429 1.000 rs4074915 chr17:79579230 G/A cg18240062 chr17:79603768 NPLOC4 -0.67 -6.84 -0.52 3.23e-10 Eye color traits; TGCT cis rs2153535 0.580 rs9406159 chr6:8464859 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.42e-8 Motion sickness; TGCT cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs295140 0.967 rs4673906 chr2:201163812 G/T cg04283868 chr2:201171347 SPATS2L 0.63 6.39 0.5 3.03e-9 QT interval; TGCT cis rs9393692 0.627 rs2179517 chr6:26198845 G/C cg05868516 chr6:26286170 HIST1H4H 0.52 5.18 0.42 8.72e-7 Educational attainment; TGCT cis rs7824557 0.628 rs11782706 chr8:11186215 A/C cg21775007 chr8:11205619 TDH 0.66 6.47 0.5 2.08e-9 Retinal vascular caliber; TGCT cis rs854765 0.647 rs7211714 chr17:17986955 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.69 7.2 0.54 5.04e-11 Total body bone mineral density; TGCT cis rs11864453 0.612 rs12924413 chr16:72129745 T/C cg14768367 chr16:72042858 DHODH 0.52 5.27 0.43 5.78e-7 Fibrinogen levels; TGCT cis rs1692580 0.774 rs10797416 chr1:2182342 T/C cg24578937 chr1:2090814 PRKCZ 0.24 5.25 0.43 6.42e-7 Coronary artery disease; TGCT cis rs477895 0.713 rs67546972 chr11:63962162 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 6.47 0.5 2.06e-9 Mean platelet volume; TGCT cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Vitiligo; TGCT cis rs6088590 0.561 rs6088527 chr20:33155841 C/T cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT trans rs783396 0.792 rs783418 chr6:106962679 G/C cg09013229 chr1:225332226 DNAH14 -0.53 -6.66 -0.51 8.13e-10 Stroke; TGCT cis rs4076764 0.958 rs11580702 chr1:163385523 C/G cg24596788 chr1:163392923 NA -0.18 -5.11 -0.42 1.19e-6 Motion sickness; TGCT cis rs6901250 0.569 rs594940 chr6:117090358 C/T cg12892004 chr6:117198278 RFX6 0.38 4.79 0.4 4.68e-6 C-reactive protein levels; TGCT cis rs854765 0.718 rs7224815 chr17:17845800 A/T cg09796270 chr17:17721594 SREBF1 0.27 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs1355223 0.583 rs1549789 chr11:34867947 G/A cg11058730 chr11:34937778 PDHX;APIP 0.75 8.13 0.59 3.8e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs75686122 0.892 rs2028083 chr8:104515794 T/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9894429 0.809 rs9889642 chr17:79591762 T/C cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs6545883 0.929 rs2593635 chr2:61634706 A/C cg15711740 chr2:61764176 XPO1 0.59 5.4 0.44 3.28e-7 Tuberculosis; TGCT cis rs2204008 0.658 rs11181310 chr12:38315963 C/A cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.76e-11 Bladder cancer; TGCT cis rs9653442 0.835 rs11885529 chr2:100746935 A/G cg07810366 chr2:100720526 AFF3 -0.47 -7.79 -0.57 2.36e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs12174631 chr6:26373150 C/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs739496 0.579 rs7488629 chr12:112273500 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs28595532 0.841 rs112953035 chr4:119752450 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4654899 0.680 rs4654874 chr1:21156667 C/T cg01072550 chr1:21505969 NA -0.55 -8.7 -0.62 1.66e-14 Superior frontal gyrus grey matter volume; TGCT cis rs9388451 0.531 rs9401850 chr6:126151000 T/G cg05901451 chr6:126070800 HEY2 -0.74 -7.68 -0.57 4.2e-12 Brugada syndrome; TGCT cis rs56104184 0.775 rs3760785 chr19:49403178 G/T cg17863274 chr19:49399704 TULP2 -0.53 -7.38 -0.55 1.97e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs1055129 0.560 rs2666003 chr17:73942976 G/A cg08125733 chr17:73851984 WBP2 0.57 5.29 0.43 5.29e-7 White matter hyperintensity burden; TGCT cis rs7552404 1.000 rs4949872 chr1:76131392 C/G cg10523679 chr1:76189770 ACADM 0.93 10.24 0.68 3.34e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7524258 0.868 rs7544314 chr1:7266744 G/C cg07173049 chr1:7289937 CAMTA1 0.31 5.29 0.43 5.39e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7565124 0.909 rs6747473 chr2:20252008 C/G cg00462460 chr2:20212509 MATN3 -0.44 -4.66 -0.39 8.07e-6 Major depressive disorder; TGCT cis rs28595532 0.920 rs114924396 chr4:119755621 A/G cg21605333 chr4:119757512 SEC24D 1.62 7.49 0.56 1.1e-11 Cannabis dependence symptom count; TGCT cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs896854 0.548 rs574183 chr8:95973816 A/G cg13393036 chr8:95962371 TP53INP1 0.54 6.59 0.51 1.11e-9 Type 2 diabetes; TGCT cis rs9894429 1.000 rs7406003 chr17:79597597 C/T cg18240062 chr17:79603768 NPLOC4 0.69 7.22 0.54 4.67e-11 Eye color traits; TGCT cis rs7809950 0.678 rs62482507 chr7:107024488 T/G cg23024343 chr7:107201750 COG5 -0.45 -6.07 -0.48 1.42e-8 Coronary artery disease; TGCT cis rs2201728 0.967 rs12512084 chr4:100173159 A/G cg07219303 chr4:100140905 ADH6 -0.35 -5.21 -0.42 7.63e-7 Cardiac Troponin-T levels; TGCT cis rs7191700 0.511 rs8058983 chr16:11360849 A/G cg00044050 chr16:11439710 C16orf75 -0.81 -8.38 -0.6 9.95e-14 Multiple sclerosis; TGCT cis rs2439831 1.000 rs7173487 chr15:43750239 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.75 4.8 0.4 4.55e-6 Lung cancer in ever smokers; TGCT cis rs6728642 0.572 rs13387563 chr2:97600916 C/A cg26665480 chr2:98280029 ACTR1B -0.91 -6.94 -0.53 1.9e-10 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs6540559 0.546 rs735693 chr1:210033988 A/C cg23283495 chr1:209979779 IRF6 0.73 5.67 0.45 9.34e-8 Cleft lip with or without cleft palate; TGCT cis rs1865760 0.566 rs3752420 chr6:26027135 G/A cg17042849 chr6:26104293 HIST1H4C -0.61 -5.3 -0.43 5.08e-7 Height; TGCT cis rs8028182 0.537 rs4371118 chr15:75898890 C/G cg20655648 chr15:75932815 IMP3 0.65 4.93 0.4 2.61e-6 Sudden cardiac arrest; TGCT trans rs2727020 0.615 rs35423199 chr11:49514914 T/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.1 -0.54 8.32e-11 Coronary artery disease; TGCT cis rs9467603 0.566 rs13212936 chr6:25588815 C/T cg16898833 chr6:26189333 HIST1H4D 1.0 4.51 0.38 1.49e-5 Intelligence (multi-trait analysis); TGCT cis rs4494114 1.000 rs9438973 chr1:39344879 G/A cg25970120 chr1:39325951 RRAGC -0.57 -5.57 -0.45 1.48e-7 Blood protein levels; TGCT cis rs11190604 1.000 rs4919466 chr10:102241213 T/C cg16342193 chr10:102329863 NA -0.39 -5.17 -0.42 9.29e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs17376456 0.877 rs10213956 chr5:93460839 C/T cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs7659604 0.539 rs2063165 chr4:122750005 A/G cg20573242 chr4:122745356 CCNA2 0.63 5.59 0.45 1.37e-7 Type 2 diabetes; TGCT cis rs7568458 0.709 rs56819945 chr2:85755139 C/T cg17127132 chr2:85788382 GGCX 0.51 4.58 0.38 1.12e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9393777 0.513 rs9295702 chr6:26634040 T/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.51 -4.68 -0.39 7.36e-6 Intelligence (multi-trait analysis); TGCT cis rs13326165 0.715 rs11709658 chr3:52399627 G/A cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.36e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs3858526 0.508 rs10838734 chr11:5876325 T/G cg13902645 chr11:5959945 NA -0.49 -5.11 -0.42 1.2e-6 DNA methylation (variation); TGCT cis rs13191362 0.935 rs67368176 chr6:162968436 A/T cg21926612 chr6:163149169 PACRG;PARK2 0.64 4.8 0.4 4.48e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs780096 0.546 rs1647284 chr2:27608115 C/T cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.46 -0.37 1.84e-5 Total body bone mineral density; TGCT cis rs13191362 1.000 rs34655790 chr6:163202739 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.12 8.19 0.59 2.72e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.830 rs28867388 chr4:98962794 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12451471 0.500 rs8077056 chr17:78076006 C/T cg06718696 chr17:78121285 EIF4A3 0.69 5.48 0.44 2.25e-7 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs6831352 0.734 rs2602857 chr4:100030318 G/A cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs2066819 1.000 rs2306693 chr12:56680531 T/C cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs7267979 1.000 rs4815412 chr20:25350325 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs981844 0.775 rs62323975 chr4:154737617 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.88 0.62 6.23e-15 Response to statins (LDL cholesterol change); TGCT cis rs1372520 0.567 rs2619349 chr4:90746646 G/T cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs11098499 0.863 rs12508173 chr4:120318526 T/C cg09307838 chr4:120376055 NA 0.65 6.17 0.48 8.93e-9 Corneal astigmatism; TGCT cis rs60843830 1.000 rs55946380 chr2:268293 A/G cg00108164 chr2:264199 ACP1;SH3YL1 0.71 6.79 0.52 4.24e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs4252435 0.614 rs4252526 chr7:142603041 T/C cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs12477438 0.822 rs6727170 chr2:99588042 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.62 -4.89 -0.4 3.1e-6 Chronic sinus infection; TGCT cis rs2887571 0.580 rs2887570 chr12:1637787 A/G cg01940102 chr12:1095972 NA 0.25 4.66 0.39 8.17e-6 Bone mineral density; TGCT cis rs3099143 1.000 rs3099137 chr15:77123626 G/A cg21673338 chr15:77095150 SCAPER -0.51 -4.88 -0.4 3.17e-6 Recalcitrant atopic dermatitis; TGCT cis rs17197710 0.621 rs12576935 chr11:47246542 G/A cg13308137 chr11:47528955 CUGBP1 0.42 5.99 0.47 2.11e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6933660 0.800 rs9383900 chr6:151782816 A/C cg14262678 chr6:151773367 RMND1;C6orf211 0.53 5.03 0.41 1.67e-6 Menarche (age at onset); TGCT cis rs13191362 0.810 rs35509380 chr6:163053028 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.03 7.35 0.55 2.37e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2180341 0.920 rs4472373 chr6:127705983 G/A cg27446573 chr6:127587934 RNF146 1.16 10.52 0.69 6.95e-19 Breast cancer; TGCT cis rs9527 0.590 rs7092029 chr10:104823909 A/T cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs12188164 0.714 rs11741954 chr5:421455 G/T cg26850624 chr5:429559 AHRR -0.21 -4.99 -0.41 1.98e-6 Cystic fibrosis severity; TGCT cis rs492146 0.765 rs597348 chr6:52845397 C/G cg06706454 chr6:52930286 FBXO9 -0.5 -4.44 -0.37 1.99e-5 Epilepsy (remission after treatment); TGCT cis rs797680 0.964 rs547866 chr1:93725053 C/T cg17826107 chr1:92977322 EVI5 0.24 5.33 0.43 4.45e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs67311347 1.000 rs2305522 chr3:40429358 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.29e-6 Renal cell carcinoma; TGCT cis rs7646507 1.000 rs7644191 chr3:172520818 G/C cg10532262 chr3:172428426 NCEH1 0.97 4.9 0.4 2.89e-6 Obesity-related traits; TGCT cis rs9467711 1.000 rs1883215 chr6:26314233 G/C cg02458000 chr6:26745757 NA -1.05 -5.54 -0.45 1.75e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2070488 0.775 rs2070489 chr3:38519424 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.53 0.56 9.15e-12 Electrocardiographic conduction measures; TGCT cis rs9527 0.615 rs4919685 chr10:104587362 G/T cg04362960 chr10:104952993 NT5C2 0.64 5.42 0.44 3.02e-7 Arsenic metabolism; TGCT cis rs7666738 0.519 rs11732209 chr4:98801643 A/G cg18180107 chr4:99064573 C4orf37 0.52 4.57 0.38 1.16e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs3617 0.625 rs2336558 chr3:52886240 C/T cg10802521 chr3:52805072 NEK4 0.6 6.93 0.53 2.07e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6598955 0.671 rs11247904 chr1:26621804 G/A cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg01411255 chr17:61851458 DDX42;CCDC47 1.1 14.88 0.8 2.36e-29 Height; TGCT cis rs7605378 0.528 rs7592587 chr2:200786516 C/G cg19045956 chr2:200819837 C2orf60;C2orf47 0.54 5.74 0.46 6.88e-8 Osteoporosis; TGCT trans rs9951602 0.512 rs9946120 chr18:76654548 A/T cg02800362 chr5:177631904 HNRNPAB 1.14 12.55 0.75 7.84e-24 Obesity-related traits; TGCT cis rs4319547 0.915 rs10734924 chr12:123018894 T/G cg23029597 chr12:123009494 RSRC2 -0.32 -5.22 -0.42 7.44e-7 Body mass index; TGCT cis rs7104764 1.000 rs10902113 chr11:245523 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs7178572 0.568 rs11857294 chr15:77596725 C/T cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs7226408 0.749 rs11664744 chr18:34435111 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs9894429 0.789 rs9747336 chr17:79584189 C/T cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs739496 0.947 rs12580300 chr12:111849271 G/A cg10833066 chr12:111807467 FAM109A 0.37 4.95 0.41 2.32e-6 Platelet count; TGCT cis rs3812831 0.629 rs7318527 chr13:114946956 C/T cg06611532 chr13:114900021 NA 0.35 6.42 0.5 2.62e-9 Schizophrenia; TGCT cis rs5769707 0.642 rs135880 chr22:50018654 T/A cg05373962 chr22:49881684 NA -0.3 -5.25 -0.43 6.29e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs8177253 0.965 rs4854760 chr3:133498741 C/T cg11941060 chr3:133502564 NA 0.29 6.13 0.48 1.09e-8 Iron status biomarkers; TGCT cis rs904251 0.737 rs914347 chr6:37484970 A/C cg01843034 chr6:37503916 NA -0.5 -6.05 -0.48 1.6e-8 Cognitive performance; TGCT cis rs2295359 0.892 rs72676067 chr1:67658803 G/A cg12940439 chr1:67600707 NA 0.6 6.2 0.49 7.79e-9 Psoriasis; TGCT cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs3820068 0.581 rs72645877 chr1:15928106 G/T cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs6121246 0.954 rs6060992 chr20:30431255 G/T cg18721089 chr20:30220636 NA -0.45 -4.98 -0.41 2.12e-6 Mean corpuscular hemoglobin; TGCT cis rs611744 0.967 rs631031 chr8:109190032 G/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs7523050 0.643 rs7551142 chr1:109399710 G/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg03806693 chr22:41940476 POLR3H -1.12 -12.98 -0.76 7.45e-25 Vitiligo; TGCT cis rs73001065 0.551 rs10424702 chr19:19508013 A/G cg03709012 chr19:19516395 GATAD2A 0.96 5.31 0.43 4.93e-7 LDL cholesterol; TGCT cis rs9926296 0.656 rs2376883 chr16:89826926 A/G cg27121462 chr16:89883253 FANCA 0.54 4.97 0.41 2.14e-6 Vitiligo; TGCT cis rs4478858 0.647 rs10798835 chr1:31709055 T/C cg00250761 chr1:31883323 NA -0.26 -4.71 -0.39 6.49e-6 Alcohol dependence; TGCT cis rs7666738 0.830 rs7662596 chr4:99019962 G/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs17539620 0.624 rs12665520 chr6:154835273 C/T cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs12220898 0.749 rs4838481 chr10:50477364 T/C cg06072769 chr10:50146962 WDFY4 0.35 4.5 0.37 1.56e-5 Inflammatory biomarkers; TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs67072384 1.000 rs11235577 chr11:72451380 C/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs7945705 0.840 rs10840136 chr11:8885024 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.41 -4.5 -0.37 1.56e-5 Hemoglobin concentration; TGCT cis rs17331151 0.505 rs79993196 chr3:52697566 T/C cg24616795 chr3:53032891 SFMBT1 0.58 4.85 0.4 3.59e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs67072384 0.818 rs12287481 chr11:72472336 A/C cg03713592 chr11:72463424 ARAP1 1.02 5.24 0.43 6.8e-7 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs155076 1.000 rs2478824 chr13:21844144 G/C cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs9443189 0.570 rs9343316 chr6:76411800 G/A cg01950844 chr6:76311363 SENP6 1.0 6.24 0.49 6.35e-9 Prostate cancer; TGCT cis rs151997 0.925 rs26089 chr5:50172251 A/G cg06027927 chr5:50259733 NA -0.45 -4.58 -0.38 1.11e-5 Callous-unemotional behaviour; TGCT cis rs7666738 0.830 rs6852015 chr4:99054373 C/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs17324807 chr4:119770638 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs769267 1.000 rs2301669 chr19:19453560 C/A cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs28374715 0.532 rs316607 chr15:41772693 G/A cg18705301 chr15:41695430 NDUFAF1 -0.93 -17.19 -0.84 1.29e-34 Ulcerative colitis; TGCT cis rs2562456 0.833 rs2562507 chr19:21726337 C/T cg01304269 chr19:21688519 ZNF429 -0.54 -4.56 -0.38 1.22e-5 Pain; TGCT cis rs7809950 1.000 rs2520277 chr7:107130234 C/T cg23024343 chr7:107201750 COG5 -0.34 -5.45 -0.44 2.58e-7 Coronary artery disease; TGCT cis rs9948 0.655 rs6576981 chr2:97394406 G/C cg01990225 chr2:97406019 LMAN2L -0.94 -5.33 -0.43 4.44e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg05665937 chr4:1216051 CTBP1 0.24 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs10193935 0.901 rs12620021 chr2:42477034 T/C cg27598129 chr2:42591480 NA -0.38 -5.29 -0.43 5.36e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7226408 0.857 rs17652769 chr18:34731828 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs4601821 0.858 rs4938012 chr11:113259654 A/G cg14159747 chr11:113255604 NA 0.38 4.51 0.38 1.5e-5 Alcoholic chronic pancreatitis; TGCT cis rs1865760 0.566 rs1800702 chr6:26086463 C/G cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs7647973 0.696 rs7100 chr3:49053219 A/G cg05785598 chr3:49045655 WDR6 0.39 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs3749237 0.537 rs4459909 chr3:49469217 T/C cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs7072216 0.806 rs9804285 chr10:100169472 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT trans rs208520 0.954 rs12190073 chr6:66983740 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs478304 0.651 rs11227281 chr11:65496558 T/C cg10518572 chr11:65560635 OVOL1 -0.24 -4.68 -0.39 7.53e-6 Acne (severe); TGCT cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6089829 0.962 rs11086151 chr20:61664644 C/T cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7772486 0.623 rs735535 chr6:146036829 C/T cg05347473 chr6:146136440 FBXO30 -0.49 -4.62 -0.38 9.3e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2760061 0.598 rs605410 chr1:228116281 A/G cg02753203 chr1:228287806 NA -0.34 -6.57 -0.51 1.23e-9 Diastolic blood pressure; TGCT cis rs35306767 0.714 rs12777800 chr10:1070361 G/A cg20503657 chr10:835505 NA 0.6 6.95 0.53 1.88e-10 Eosinophil percentage of granulocytes; TGCT cis rs2153535 0.601 rs2143352 chr6:8530248 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs8016982 0.674 rs759939 chr14:81663453 G/C cg01989461 chr14:81687754 GTF2A1 0.78 7.94 0.58 1.06e-12 Schizophrenia; TGCT cis rs4372836 0.729 rs10865508 chr2:29053704 G/C cg09522027 chr2:28974177 PPP1CB 0.67 6.89 0.53 2.45e-10 Body mass index; TGCT cis rs921968 0.643 rs833083 chr2:219336959 A/T cg02176678 chr2:219576539 TTLL4 -0.38 -5.48 -0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs4499344 0.696 rs2868153 chr19:33099277 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.79 0.62 1.01e-14 Mean platelet volume; TGCT cis rs1367858 0.654 rs994280 chr2:201240086 A/G cg04283868 chr2:201171347 SPATS2L 0.51 4.55 0.38 1.28e-5 Schizophrenia; TGCT cis rs7809950 0.798 rs10281535 chr7:107229618 T/G cg23024343 chr7:107201750 COG5 0.35 5.41 0.44 3.18e-7 Coronary artery disease; TGCT cis rs763014 0.898 rs916414 chr16:632073 C/T cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs5750830 0.649 rs6001588 chr22:39819049 G/C cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs8135665 0.600 rs3026682 chr22:38452482 G/A cg13116946 chr22:38479732 SLC16A8 0.31 5.88 0.47 3.52e-8 Advanced age-related macular degeneration;Age-related macular degeneration; TGCT cis rs908922 0.651 rs548252 chr1:152489742 A/G cg20991723 chr1:152506922 NA -0.46 -6.37 -0.5 3.39e-9 Hair morphology; TGCT cis rs4389656 1.000 rs4389656 chr5:6753728 A/G cg10857441 chr5:6722123 POLS -0.22 -4.45 -0.37 1.87e-5 Coronary artery disease; TGCT cis rs9650657 0.537 rs7016385 chr8:10779472 A/G cg27411982 chr8:10470053 RP1L1 0.22 4.87 0.4 3.32e-6 Neuroticism; TGCT cis rs909002 0.830 rs10914461 chr1:32113217 G/A cg11573219 chr1:32083031 HCRTR1 -0.41 -5.26 -0.43 6.14e-7 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.791 rs1280276 chr6:145892350 A/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.58 -0.38 1.11e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.617 rs598353 chr11:68635770 C/A cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7180079 0.502 rs8033972 chr15:64524980 G/A cg02848875 chr15:64387786 SNX1 -0.35 -5.37 -0.43 3.7e-7 Monocyte count; TGCT trans rs7618501 1.000 rs1049256 chr3:49763338 T/C cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.715 rs55724082 chr17:47017879 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.5 -0.37 1.53e-5 Type 2 diabetes; TGCT cis rs6141769 0.542 rs6057627 chr20:31306728 C/G cg13636640 chr20:31349939 DNMT3B -0.51 -4.48 -0.37 1.68e-5 Subjective well-being; TGCT cis rs12477438 0.798 rs10167015 chr2:99570707 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.33 -0.49 4.07e-9 Chronic sinus infection; TGCT cis rs9916302 0.718 rs7219909 chr17:37706243 C/T cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs41308713 0.681 rs8116426 chr20:37034643 A/C cg09132763 chr20:37064059 LOC388796;SNORA71D 1.26 5.95 0.47 2.53e-8 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs295140 0.647 rs295129 chr2:201229473 G/A cg04283868 chr2:201171347 SPATS2L -0.54 -5.22 -0.42 7.46e-7 QT interval; TGCT cis rs986417 0.606 rs4899014 chr14:61118783 C/T cg27398547 chr14:60952738 C14orf39 1.69 9.43 0.65 3.06e-16 Gut microbiota (bacterial taxa); TGCT cis rs6866344 0.570 rs59259518 chr5:178142628 C/T cg03877680 chr5:178157825 ZNF354A 0.75 6.39 0.5 3.03e-9 Neutrophil percentage of white cells; TGCT cis rs2594989 0.779 rs62245949 chr3:11575969 C/G cg00170343 chr3:11313890 ATG7 -0.67 -5.24 -0.43 6.68e-7 Circulating chemerin levels; TGCT cis rs12220238 1.000 rs11000897 chr10:75911276 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT trans rs1005277 0.505 rs13503 chr10:38239843 C/A cg17830980 chr10:43048298 ZNF37B 0.73 8.35 0.6 1.13e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7666738 0.830 rs4502686 chr4:98765117 T/C cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs25422 0.938 rs9489443 chr6:118886163 T/A cg21191810 chr6:118973309 C6orf204 -0.38 -4.86 -0.4 3.47e-6 Renal cell carcinoma; TGCT cis rs72781680 0.948 rs72790326 chr2:24126153 C/T cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs9611565 0.694 rs5758389 chr22:41941749 T/C cg03806693 chr22:41940476 POLR3H -1.01 -11.48 -0.72 3.1e-21 Vitiligo; TGCT cis rs1008375 0.966 rs3775924 chr4:17585984 T/C cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6693567 0.545 rs4451552 chr1:150455854 C/G cg09579323 chr1:150459698 TARS2 0.49 4.44 0.37 1.96e-5 Migraine; TGCT cis rs3751972 0.681 rs2108952 chr17:26181865 C/T cg02948944 chr17:26242737 NA 0.4 5.62 0.45 1.18e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs1008375 0.966 rs1860591 chr4:17577329 A/G cg10189774 chr4:17578691 LAP3 0.57 5.13 0.42 1.08e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2730260 0.537 rs73169239 chr7:158884305 C/A cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs950169 0.922 rs12910334 chr15:84958318 G/A cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs4819052 0.808 rs2246697 chr21:46689999 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9660180 0.836 rs72634845 chr1:1704899 G/A cg13866156 chr1:1669148 SLC35E2 -0.24 -5.87 -0.47 3.74e-8 Body mass index; TGCT cis rs986417 1.000 rs1254323 chr14:60908378 G/A cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs3784262 0.528 rs11071364 chr15:58334113 C/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.39 -0.5 3.11e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs709400 0.663 rs62007684 chr14:103894223 T/C cg12935359 chr14:103987150 CKB -0.34 -4.87 -0.4 3.35e-6 Body mass index; TGCT cis rs909002 0.887 rs10914463 chr1:32132063 C/T cg11573219 chr1:32083031 HCRTR1 -0.43 -5.41 -0.44 3.14e-7 Intelligence (multi-trait analysis); TGCT cis rs9318086 0.578 rs75752641 chr13:24473240 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.82 8.98 0.63 3.58e-15 Myopia (pathological); TGCT cis rs694419 0.602 rs7227643 chr18:60193628 T/C cg13506219 chr18:60193840 ZCCHC2 -0.54 -4.93 -0.4 2.57e-6 Serum albumin level; TGCT trans rs6089829 0.889 rs6090206 chr20:61668363 G/A cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9611565 0.592 rs9611613 chr22:41961831 T/C cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs67478160 0.643 rs7156697 chr14:104211136 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.37 -0.5 3.33e-9 Schizophrenia; TGCT cis rs7772486 0.720 rs6901888 chr6:146023144 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -4.85 -0.4 3.61e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9532580 0.656 rs2721068 chr13:41139712 T/C cg21288729 chr13:41239152 FOXO1 0.89 7.41 0.55 1.7e-11 Mean corpuscular hemoglobin; TGCT cis rs79349575 0.783 rs4794000 chr17:47022755 C/G cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs9611519 0.894 rs9611488 chr22:41462592 G/T cg03806693 chr22:41940476 POLR3H -0.67 -6.07 -0.48 1.45e-8 Neuroticism; TGCT cis rs3015497 0.575 rs8023035 chr14:51162419 A/G cg04730355 chr14:51134070 SAV1 -0.59 -5.68 -0.45 9.22e-8 Mean platelet volume; TGCT cis rs9611565 0.694 rs4822032 chr22:41925535 T/C cg06634786 chr22:41940651 POLR3H -0.77 -7.72 -0.57 3.42e-12 Vitiligo; TGCT cis rs259282 0.669 rs731673 chr19:33132295 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.64 5.99 0.47 2.08e-8 Schizophrenia; TGCT cis rs7824557 0.564 rs6601584 chr8:11232343 C/G cg21775007 chr8:11205619 TDH -0.62 -5.96 -0.47 2.44e-8 Retinal vascular caliber; TGCT cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg19454999 chr17:41278357 BRCA1;NBR2 -0.52 -5.48 -0.44 2.3e-7 Menopause (age at onset); TGCT cis rs1878931 0.697 rs10048148 chr16:3417450 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 11.98 0.73 1.97e-22 Body mass index (adult); TGCT cis rs9467773 0.844 rs2393669 chr6:26503873 C/T cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.518 rs13133925 chr4:98706398 G/T cg17366294 chr4:99064904 C4orf37 0.62 5.77 0.46 6.03e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7552404 0.690 rs12723575 chr1:76335203 T/C cg22875332 chr1:76189707 ACADM -0.57 -6.14 -0.48 1.05e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg18402987 chr7:1209562 NA 0.7 5.74 0.46 6.77e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11785400 0.793 rs13255558 chr8:143748080 C/T cg24634471 chr8:143751801 JRK 0.55 5.38 0.44 3.52e-7 Schizophrenia; TGCT cis rs7267979 0.586 rs6050432 chr20:25184028 T/C cg03522245 chr20:25566470 NINL 0.5 5.27 0.43 5.88e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6669384 0.774 rs4844624 chr1:208035446 A/G cg22525895 chr1:207977042 MIR29B2 -0.39 -5.53 -0.44 1.82e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs35934224 0.843 rs34175429 chr22:19867276 T/C cg11182965 chr22:19864308 TXNRD2 -0.38 -5.37 -0.43 3.79e-7 Glaucoma (primary open-angle); TGCT cis rs12142240 0.698 rs17361763 chr1:46810670 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs2836950 0.565 rs2150414 chr21:40614988 A/G cg17971929 chr21:40555470 PSMG1 -0.52 -4.59 -0.38 1.05e-5 Menarche (age at onset); TGCT cis rs7809950 0.954 rs11977187 chr7:107210383 C/T cg23024343 chr7:107201750 COG5 0.35 5.35 0.43 4.13e-7 Coronary artery disease; TGCT cis rs3820068 0.608 rs10927836 chr1:16034368 G/C cg17385448 chr1:15911702 AGMAT 0.36 4.92 0.4 2.67e-6 Systolic blood pressure; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT trans rs9329221 0.741 rs13264066 chr8:9804075 C/G cg15556689 chr8:8085844 FLJ10661 -0.82 -7.75 -0.57 2.92e-12 Neuroticism; TGCT cis rs769267 1.000 rs2074089 chr19:19449603 G/A cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs12142240 0.698 rs72677585 chr1:46812374 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.84 0.46 4.33e-8 Menopause (age at onset); TGCT cis rs826838 0.967 rs11183022 chr12:38652519 G/A cg13010199 chr12:38710504 ALG10B 0.77 6.31 0.49 4.59e-9 Heart rate; TGCT cis rs4788570 0.615 rs7188675 chr16:71680002 C/T cg06353428 chr16:71660113 MARVELD3 1.55 12.51 0.75 9.87e-24 Intelligence (multi-trait analysis); TGCT cis rs55962025 0.824 rs61348208 chr4:3089564 C/T cg06533319 chr4:3265114 C4orf44 0.22 4.7 0.39 6.91e-6 Parental longevity (mother's age at death); TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg00024416 chr22:24240387 NA -0.25 -4.91 -0.4 2.86e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9527 0.615 rs4919682 chr10:104584330 C/T cg15744005 chr10:104629667 AS3MT -0.49 -5.77 -0.46 5.9e-8 Arsenic metabolism; TGCT cis rs6089829 0.816 rs6062397 chr20:61668268 A/G cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs899997 0.773 rs11072784 chr15:78966058 T/C cg00061860 chr15:78953028 NA -0.33 -5.21 -0.42 7.75e-7 Coronary artery disease or large artery stroke; TGCT cis rs1532993 0.518 rs10005829 chr4:98606970 A/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs8072100 0.817 rs7213086 chr17:45752310 C/G cg08085267 chr17:45401833 C17orf57 -0.47 -4.99 -0.41 2.02e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9926296 0.533 rs10852623 chr16:89865242 T/C cg03388025 chr16:89894329 SPIRE2 0.48 8.33 0.6 1.26e-13 Vitiligo; TGCT cis rs28595532 0.920 rs114649974 chr4:119735341 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs2120019 1.000 rs12324912 chr15:75361006 G/A cg09165964 chr15:75287851 SCAMP5 -1.16 -9.78 -0.66 4.33e-17 Blood trace element (Zn levels); TGCT cis rs992157 1.000 rs736730 chr2:219120255 C/T cg00012203 chr2:219082015 ARPC2 0.77 8.2 0.59 2.56e-13 Colorectal cancer; TGCT cis rs25645 0.823 rs12453334 chr17:38153473 C/T cg17467752 chr17:38218738 THRA -0.54 -4.68 -0.39 7.4e-6 Myeloid white cell count; TGCT cis rs12510870 0.634 rs10805065 chr4:74379938 C/T cg05868023 chr4:75230803 EREG 0.55 4.7 0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs9916302 0.706 rs4332770 chr17:37704712 T/C cg07936489 chr17:37558343 FBXL20 -0.84 -6.16 -0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs2637266 0.967 rs12246430 chr10:78352879 C/T cg18941641 chr10:78392320 NA 0.43 5.07 0.41 1.42e-6 Pulmonary function; TGCT cis rs11080466 1.000 rs8095990 chr18:10896602 A/G cg02393756 chr18:9912783 VAPA -0.26 -4.71 -0.39 6.56e-6 Non-small cell lung cancer; TGCT cis rs6725041 0.819 rs2049180 chr2:213081740 G/A cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs6840360 0.533 rs13121178 chr4:152729047 T/C cg22705602 chr4:152727874 NA 0.34 6.14 0.48 1.02e-8 Intelligence (multi-trait analysis); TGCT cis rs736408 0.716 rs2239549 chr3:52823126 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.24 -0.43 6.69e-7 Bipolar disorder; TGCT cis rs9467773 1.000 rs10214634 chr6:26564582 T/A cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs3935685 0.874 rs11072665 chr15:78006256 T/C cg25212270 chr15:78015279 NA 0.26 5.59 0.45 1.38e-7 Intelligence (multi-trait analysis); TGCT cis rs1018836 0.923 rs12545279 chr8:91636373 C/G cg16814680 chr8:91681699 NA -0.85 -9.0 -0.63 3.35e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg12386194 chr3:101231763 SENP7 0.51 5.0 0.41 1.9e-6 Colorectal cancer; TGCT cis rs6582630 0.519 rs8189609 chr12:38281408 A/G cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7428 0.545 rs4832163 chr2:85541083 T/C cg03728395 chr2:85555865 TGOLN2 -0.29 -5.29 -0.43 5.28e-7 Ear protrusion; TGCT cis rs1962636 1 rs1962636 chr16:22064395 A/C cg09370801 chr16:22207107 NA 0.58 5.28 0.43 5.57e-7 Schizophrenia; TGCT cis rs9929218 1.000 rs11865026 chr16:68774283 A/G cg01251360 chr16:68772225 CDH1 0.28 4.74 0.39 5.65e-6 Colorectal cancer; TGCT cis rs2486012 1.000 rs3791097 chr1:44349381 G/C cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT trans rs561341 0.769 rs8074383 chr17:30178793 C/T cg20587970 chr11:113659929 NA 0.89 9.02 0.63 2.99e-15 Hip circumference adjusted for BMI; TGCT cis rs4332037 0.575 rs55952733 chr7:2070680 G/A cg25834613 chr7:1915315 MAD1L1 -0.52 -5.11 -0.42 1.2e-6 Bipolar disorder; TGCT cis rs35160687 0.901 rs17738096 chr2:86513893 C/G cg12542933 chr2:85804724 VAMP8 0.4 4.79 0.39 4.75e-6 Night sleep phenotypes; TGCT cis rs2404602 0.692 rs12594556 chr15:77165363 G/A cg22467129 chr15:76604101 ETFA -0.47 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.57 -5.69 -0.45 8.8e-8 Intelligence (multi-trait analysis); TGCT cis rs8067545 0.640 rs10083840 chr17:19965972 A/G cg18979559 chr17:20280153 CCDC144C 0.47 4.91 0.4 2.8e-6 Schizophrenia; TGCT cis rs9910055 0.762 rs2526020 chr17:42216588 G/T cg19774624 chr17:42201019 HDAC5 -0.85 -8.95 -0.63 4.27e-15 Total body bone mineral density; TGCT cis rs2718812 0.792 rs1867503 chr3:133410648 G/A cg08048268 chr3:133502702 NA 0.38 4.66 0.39 8.01e-6 Iron status biomarkers; TGCT cis rs4665809 1.000 rs6546726 chr2:26275116 A/G cg25036284 chr2:26402008 FAM59B -0.57 -5.0 -0.41 1.94e-6 Gut microbiome composition (summer); TGCT cis rs8014204 0.816 rs11159107 chr14:75341266 C/A cg06637938 chr14:75390232 RPS6KL1 -0.53 -4.6 -0.38 1.04e-5 Caffeine consumption; TGCT cis rs7267979 0.844 rs1555330 chr20:25232097 A/C cg14121845 chr20:25566513 NINL 0.49 4.96 0.41 2.24e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13191362 1.000 rs35017019 chr6:162982581 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6901250 0.851 rs168128 chr6:117166865 A/G cg12892004 chr6:117198278 RFX6 -0.54 -6.66 -0.51 7.82e-10 C-reactive protein levels; TGCT cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs7302981 0.934 rs7532 chr12:50523964 T/C cg23855989 chr12:50355821 AQP5 -0.3 -4.44 -0.37 2e-5 Systolic blood pressure; TGCT cis rs11605924 0.901 rs7112505 chr11:45840939 A/T ch.11.939596F chr11:45881766 CRY2 -0.35 -4.47 -0.37 1.76e-5 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs13256369 0.802 rs4840350 chr8:8561442 A/G cg18904891 chr8:8559673 CLDN23 0.57 5.27 0.43 5.87e-7 Obesity-related traits; TGCT cis rs1901167 0.908 rs1996343 chr5:40978926 C/T cg02441090 chr5:41871058 OXCT1 -0.31 -4.61 -0.38 9.86e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs13191362 0.935 rs34035978 chr6:163165336 G/C cg06582575 chr6:163149167 PACRG;PARK2 0.66 5.66 0.45 1.01e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2562456 0.917 rs2681392 chr19:21695987 T/G cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs6570726 0.599 rs9376951 chr6:145898911 C/T cg23711669 chr6:146136114 FBXO30 0.7 6.45 0.5 2.23e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.601 rs9505474 chr6:8539794 C/G cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg04944784 chr2:26401820 FAM59B -0.78 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT cis rs2299587 0.610 rs6987474 chr8:17773298 T/C cg01800426 chr8:17659068 MTUS1 -0.7 -6.03 -0.48 1.72e-8 Economic and political preferences; TGCT cis rs727563 0.593 rs132770 chr22:42017264 A/G cg06634786 chr22:41940651 POLR3H 0.88 8.33 0.6 1.28e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs367615 0.879 rs2201015 chr5:108947450 C/T cg17395555 chr5:108820864 NA 0.29 4.84 0.4 3.84e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs950776 0.714 rs660652 chr15:78887832 A/G cg06917634 chr15:78832804 PSMA4 -0.65 -5.33 -0.43 4.48e-7 Sudden cardiac arrest; TGCT cis rs2797160 0.967 rs2797159 chr6:126009557 G/A cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs13217239 0.646 rs10946898 chr6:27003884 T/C cg26531700 chr6:26746687 NA 0.68 6.86 0.52 2.83e-10 Schizophrenia; TGCT cis rs2836974 0.644 rs1882779 chr21:40690938 T/C cg17971929 chr21:40555470 PSMG1 -0.64 -5.55 -0.45 1.68e-7 Cognitive function; TGCT cis rs1218582 0.688 rs58629129 chr1:154910930 T/C cg06221963 chr1:154839813 KCNN3 -0.7 -11.65 -0.72 1.22e-21 Prostate cancer; TGCT cis rs736408 0.677 rs2286798 chr3:52821177 G/T cg07507251 chr3:52567010 NT5DC2 -0.49 -6.75 -0.52 4.96e-10 Bipolar disorder; TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg22166914 chr1:53195759 ZYG11B 0.3 4.8 0.4 4.46e-6 Monocyte count; TGCT cis rs17221829 0.703 rs11018680 chr11:89364011 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs11648796 0.717 rs10682 chr16:767430 C/G cg07343612 chr16:622815 PIGQ -0.35 -5.07 -0.41 1.43e-6 Height; TGCT cis rs12762955 0.677 rs11250267 chr10:1156487 A/G cg26597838 chr10:835615 NA 0.5 5.56 0.45 1.55e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs6754311 0.731 rs892715 chr2:136576577 T/C cg07169764 chr2:136633963 MCM6 -0.61 -5.61 -0.45 1.25e-7 Mosquito bite size; TGCT cis rs2019216 0.500 rs12450390 chr17:21910636 G/T cg22648282 chr17:21454238 C17orf51 -0.6 -5.54 -0.45 1.75e-7 Pelvic organ prolapse; TGCT cis rs2549003 1.000 rs6873426 chr5:131818631 G/T cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs2301573 1.000 rs61319406 chr3:129307957 T/G cg07730360 chr3:128845626 NA 0.33 4.61 0.38 9.84e-6 Hip circumference; TGCT cis rs9788721 0.836 rs55983731 chr15:78735269 C/T cg18825076 chr15:78729989 IREB2 -0.33 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs1403694 0.695 rs5029969 chr3:186434405 G/T cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs7666738 0.830 rs4443293 chr4:99063120 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs539096 0.830 rs3000761 chr1:44026089 C/T cg12908607 chr1:44402522 ARTN 0.5 5.25 0.43 6.3e-7 Intelligence (multi-trait analysis); TGCT cis rs6952808 1.000 rs6978048 chr7:1886872 T/G cg22963979 chr7:1858916 MAD1L1 -0.36 -5.62 -0.45 1.21e-7 Bipolar disorder and schizophrenia; TGCT cis rs2997447 0.761 rs56078964 chr1:26442600 C/A cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs860554 0.705 rs700469 chr1:201259981 C/T cg01022117 chr1:201258280 PKP1 0.32 4.88 0.4 3.15e-6 Panic disorder; TGCT cis rs12497850 0.931 rs9840684 chr3:48893780 T/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs7772486 0.686 rs857877 chr6:145976230 A/C cg23711669 chr6:146136114 FBXO30 -0.86 -9.6 -0.65 1.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs17102423 0.602 rs1270073 chr14:65566257 C/A cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.57e-9 Obesity-related traits; TGCT cis rs11096990 0.892 rs1473364 chr4:39212879 A/G ch.4.37949012R chr4:38272617 NA 0.38 4.67 0.39 7.82e-6 Cognitive function; TGCT cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg15659132 chr6:26577336 NA 0.87 11.0 0.7 4.77e-20 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.649 rs139559 chr22:42191636 A/G cg06481639 chr22:41940642 POLR3H -0.55 -4.75 -0.39 5.55e-6 Vitiligo; TGCT cis rs3008870 0.583 rs3008892 chr1:67373558 A/T cg11518657 chr1:67396239 MIER1 0.56 4.54 0.38 1.29e-5 Lymphocyte percentage of white cells; TGCT cis rs6725041 0.819 rs10196229 chr2:213081987 C/T cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT cis rs4713118 0.513 rs156738 chr6:28014025 G/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.75 0.39 5.48e-6 Parkinson's disease; TGCT cis rs4242434 0.927 rs2291231 chr8:22463912 C/T cg21658235 chr8:22456391 C8orf58 0.43 4.47 0.37 1.72e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7223966 1.000 rs7216798 chr17:61740963 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.05 0.41 1.51e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2074038 1.000 rs2074038 chr11:44087989 G/T cg15894661 chr11:44088124 ACCS -0.6 -4.44 -0.37 2e-5 IgA nephropathy; TGCT cis rs12753569 0.967 rs6696116 chr1:76483732 C/T cg00791851 chr1:76518896 NA -0.36 -4.58 -0.38 1.14e-5 Personality dimensions; TGCT cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs9788721 0.836 rs17483929 chr15:78742376 C/T cg18825076 chr15:78729989 IREB2 -0.33 -5.1 -0.42 1.25e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg20818283 chr2:191399100 TMEM194B 0.47 4.55 0.38 1.25e-5 Pulse pressure; TGCT cis rs17401966 1.000 rs12118323 chr1:10469641 A/G cg19773385 chr1:10388646 KIF1B -0.23 -5.42 -0.44 2.97e-7 Hepatocellular carcinoma; TGCT cis rs4889855 0.530 rs4889865 chr17:78568447 A/T cg16591659 chr17:78472290 NA 0.28 4.46 0.37 1.84e-5 Fractional excretion of uric acid; TGCT trans rs2832077 0.527 rs2250141 chr21:30241984 A/T cg14791747 chr16:20752902 THUMPD1 -1.0 -10.45 -0.68 1e-18 Cognitive test performance; TGCT cis rs7010267 0.570 rs28893333 chr8:120046473 A/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg03396347 chr1:1875803 NA -0.38 -6.9 -0.53 2.33e-10 Body mass index; TGCT cis rs11658309 1 rs11658309 chr17:17762247 T/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.75 -7.78 -0.57 2.42e-12 Strep throat; TGCT cis rs7249142 0.549 rs741706 chr19:19281672 C/T cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.55 0.45 1.67e-7 IgG glycosylation; TGCT cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg08645402 chr16:4508243 NA -0.19 -4.61 -0.38 9.67e-6 Schizophrenia; TGCT cis rs2070488 0.662 rs7373930 chr3:38454931 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.65 4.96 0.41 2.28e-6 Electrocardiographic conduction measures; TGCT cis rs4727027 0.901 rs6943937 chr7:148869915 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.65 0.39 8.3e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg12386194 chr3:101231763 SENP7 0.6 5.61 0.45 1.27e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs28374715 0.662 rs11852419 chr15:41456374 A/T cg18705301 chr15:41695430 NDUFAF1 0.74 10.35 0.68 1.75e-18 Ulcerative colitis; TGCT cis rs10838634 1.000 rs11038987 chr11:46792695 A/T cg18332754 chr11:46939436 LRP4 0.84 4.54 0.38 1.29e-5 Schizophrenia; TGCT cis rs4689388 0.853 rs1079214 chr4:6282157 T/C cg25554036 chr4:6271136 WFS1 0.57 7.77 0.57 2.63e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12541335 0.639 rs11779277 chr8:22200683 C/T cg18135555 chr8:22132992 PIWIL2 0.3 6.12 0.48 1.13e-8 Hypertriglyceridemia; TGCT cis rs9457247 1.000 rs2769352 chr6:167378619 A/G cg25258033 chr6:167368657 RNASET2 -0.2 -4.82 -0.4 4.19e-6 Crohn's disease; TGCT cis rs2463822 0.844 rs1919359 chr11:62055703 A/G cg06239285 chr11:62104954 ASRGL1 0.81 5.15 0.42 1.01e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7264396 0.623 rs2590984 chr20:34597031 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.96 -0.41 2.29e-6 Total cholesterol levels; TGCT cis rs875971 0.660 rs10272357 chr7:66063074 G/A cg00343986 chr7:65444356 GUSB -0.25 -5.51 -0.44 1.95e-7 Aortic root size; TGCT cis rs4654899 0.865 rs12410467 chr1:21356055 G/A cg01072550 chr1:21505969 NA -0.46 -6.95 -0.53 1.88e-10 Superior frontal gyrus grey matter volume; TGCT cis rs2832077 0.506 rs2832081 chr21:30152992 A/C cg24692254 chr21:30365293 RNF160 0.53 5.05 0.41 1.52e-6 Cognitive test performance; TGCT cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg07061783 chr6:25882402 NA -0.81 -8.85 -0.62 7.54e-15 Uric acid levels; TGCT cis rs2370759 0.945 rs10508773 chr10:32575444 C/T cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs9291683 0.526 rs6827785 chr4:10018205 C/T cg00071950 chr4:10020882 SLC2A9 0.66 7.74 0.57 3.07e-12 Bone mineral density; TGCT cis rs4654899 1.000 rs6697555 chr1:21287938 C/T cg01072550 chr1:21505969 NA -0.5 -8.13 -0.59 3.72e-13 Superior frontal gyrus grey matter volume; TGCT cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs7904368 0.568 rs7075036 chr10:16864810 C/T cg23933602 chr10:16859644 RSU1 0.7 6.5 0.5 1.81e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs7091068 0.706 rs4919398 chr10:95429162 C/T cg20715218 chr10:95462985 C10orf4 0.5 4.59 0.38 1.09e-5 Urinary tract infection frequency; TGCT trans rs2229238 0.911 rs58348886 chr1:154446198 T/C cg22838003 chr14:96730482 BDKRB1 0.41 6.87 0.53 2.78e-10 Coronary heart disease; TGCT cis rs17767294 0.614 rs72845068 chr6:27668147 A/C cg08851530 chr6:28072375 NA 1.56 7.38 0.55 1.95e-11 Parkinson's disease; TGCT cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.7 0.39 6.7e-6 Electroencephalogram traits; TGCT cis rs12286929 0.651 rs12274772 chr11:115098768 C/T cg04580443 chr11:115547056 NA -0.25 -4.67 -0.39 7.72e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12497850 0.931 rs4974087 chr3:48919232 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs111326718 1 rs111326718 chr10:104771211 A/AAAAAT cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.34e-7 Reticulocyte count; TGCT cis rs1887596 0.624 rs1546258 chr13:27134551 A/G cg01312412 chr13:27282625 NA 0.27 4.74 0.39 5.68e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs17253792 0.822 rs113649689 chr14:56088065 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6495367 1.000 rs13380104 chr15:79378821 C/T cg17916960 chr15:79447300 NA 0.36 5.13 0.42 1.06e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT trans rs7618501 0.519 rs3774750 chr3:50208406 C/G cg21659725 chr3:3221576 CRBN -0.7 -7.99 -0.58 8.03e-13 Intelligence (multi-trait analysis); TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg09704166 chr2:114031854 PAX8;LOC440839 0.33 4.89 0.4 3.1e-6 Lymphocyte counts; TGCT cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs9527 0.590 rs7894959 chr10:104756182 C/T cg04362960 chr10:104952993 NT5C2 0.65 5.64 0.45 1.08e-7 Arsenic metabolism; TGCT trans rs17685 0.753 rs10085567 chr7:75734206 A/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.38 0.6 9.94e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7824557 0.583 rs2736306 chr8:11239762 A/T cg21775007 chr8:11205619 TDH 0.68 7.3 0.55 3e-11 Retinal vascular caliber; TGCT cis rs2013441 1.000 rs9900166 chr17:20192969 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs28595532 0.920 rs115090549 chr4:119753554 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7267979 1.000 rs1888998 chr20:25291826 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs797680 0.856 rs7513705 chr1:93666349 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.81 -0.52 3.79e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg22166914 chr1:53195759 ZYG11B 0.36 5.96 0.47 2.45e-8 Monocyte count; TGCT cis rs7647973 0.626 rs11709734 chr3:49745235 G/A cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs12893668 0.572 rs4906356 chr14:104138701 C/T cg26031613 chr14:104095156 KLC1 -0.59 -5.02 -0.41 1.75e-6 Reticulocyte count; TGCT cis rs7677751 0.806 rs60806423 chr4:55086816 C/T cg17187183 chr4:55093834 PDGFRA 0.55 7.16 0.54 6.22e-11 Corneal astigmatism; TGCT cis rs6840360 0.593 rs59350867 chr4:152695935 G/A cg22705602 chr4:152727874 NA -0.34 -5.9 -0.47 3.24e-8 Intelligence (multi-trait analysis); TGCT cis rs4076764 0.830 rs10917770 chr1:163442214 G/C cg24596788 chr1:163392923 NA -0.17 -4.99 -0.41 2.01e-6 Motion sickness; TGCT cis rs2637266 0.967 rs4581393 chr10:78376123 A/C cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg04234412 chr22:24373322 LOC391322 0.92 8.38 0.6 9.67e-14 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs796364 0.507 rs13035874 chr2:201109553 G/A cg04283868 chr2:201171347 SPATS2L 0.53 5.06 0.41 1.47e-6 Schizophrenia; TGCT cis rs75229567 0.541 rs775443 chr12:70122623 C/T cg10114359 chr12:70132523 RAB3IP -1.06 -5.99 -0.47 2.14e-8 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT trans rs17471911 0.708 rs11189928 chr10:100755581 T/C cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs12681288 0.644 rs2600494 chr8:1025517 C/T cg08872321 chr8:1308229 NA -0.24 -4.45 -0.37 1.86e-5 Schizophrenia; TGCT cis rs4803468 1.000 rs284652 chr19:41928652 C/T cg09537434 chr19:41945824 ATP5SL -0.92 -10.57 -0.69 5.19e-19 Height; TGCT cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg05552183 chr6:42928497 GNMT 0.58 5.05 0.41 1.51e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs8014252 0.803 rs57339942 chr14:71083307 T/A cg11204974 chr14:71022665 NA -0.56 -4.55 -0.38 1.25e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs910316 0.763 rs735452 chr14:75497984 A/G cg11812906 chr14:75593930 NEK9 -0.58 -5.61 -0.45 1.25e-7 Height; TGCT cis rs35146811 0.700 rs7788301 chr7:99782753 C/G cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs986417 1.000 rs8015462 chr14:61046687 G/A cg27398547 chr14:60952738 C14orf39 1.48 11.08 0.71 2.96e-20 Gut microbiota (bacterial taxa); TGCT cis rs6840360 0.615 rs4696096 chr4:152475387 A/G cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT trans rs9951602 0.512 rs6506874 chr18:76653467 G/T cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs174601 0.861 rs174547 chr11:61570783 C/T cg19610905 chr11:61596333 FADS2 1.01 10.23 0.68 3.53e-18 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs6831352 0.918 rs1126672 chr4:100047812 G/A cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs7666738 0.830 rs7687315 chr4:98900613 A/G cg05340658 chr4:99064831 C4orf37 0.51 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.29e-9 Cognitive function; TGCT cis rs72945132 0.882 rs61260732 chr11:70162145 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs2742417 1.000 rs2673056 chr3:45737802 C/T cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs921968 0.643 rs1055816 chr2:219501328 G/A cg02176678 chr2:219576539 TTLL4 0.38 5.47 0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs11671005 0.735 rs3764532 chr19:58929222 G/A cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT trans rs524675 0.581 rs515965 chr4:13959797 G/A cg02315626 chr17:27188560 MIR451;MIR144 0.4 6.75 0.52 5.03e-10 Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals; TGCT cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg05368731 chr17:41323189 NBR1 1.16 13.76 0.78 1.03e-26 Menopause (age at onset); TGCT cis rs57590327 0.555 rs13099615 chr3:81729101 T/A cg07356753 chr3:81810745 GBE1 -0.77 -7.15 -0.54 6.69e-11 Extraversion; TGCT cis rs9467773 1.000 rs9467779 chr6:26536687 A/T cg09904177 chr6:26538194 HMGN4 -0.62 -6.3 -0.49 4.83e-9 Intelligence (multi-trait analysis); TGCT cis rs6460942 0.908 rs73301032 chr7:12256799 C/G cg06484146 chr7:12443880 VWDE -0.55 -4.68 -0.39 7.25e-6 Coronary artery disease; TGCT cis rs10875595 0.836 rs6889723 chr5:140676524 C/T cg20560182 chr5:140700478 TAF7 -0.64 -4.6 -0.38 1.01e-5 Pulmonary function decline; TGCT cis rs1050631 1.000 rs1107840 chr18:33707164 A/C cg25426722 chr18:33708991 SLC39A6;ELP2 0.49 4.83 0.4 3.95e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs6450176 1.000 rs3776718 chr5:53298714 G/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs9443189 0.570 rs775075 chr6:76380035 A/C cg01950844 chr6:76311363 SENP6 -1.0 -6.24 -0.49 6.35e-9 Prostate cancer; TGCT cis rs2404602 0.622 rs1567671 chr15:77209200 C/G cg22467129 chr15:76604101 ETFA 0.54 5.4 0.44 3.25e-7 Blood metabolite levels; TGCT cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg06640241 chr16:89574553 SPG7 0.65 6.44 0.5 2.34e-9 Multiple myeloma (IgH translocation); TGCT cis rs9868809 0.505 rs11708786 chr3:48752654 C/T cg00383909 chr3:49044727 WDR6 0.95 5.79 0.46 5.34e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs1218582 0.774 rs4845679 chr1:154861187 G/T cg06418219 chr1:154948305 SHC1;CKS1B -0.63 -6.3 -0.49 4.82e-9 Prostate cancer; TGCT cis rs8070740 0.592 rs2189338 chr17:5326341 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.59 5.92 0.47 2.94e-8 Menopause (age at onset); TGCT cis rs826838 0.967 rs7965656 chr12:38807244 G/A cg13010199 chr12:38710504 ALG10B 0.82 6.86 0.52 2.89e-10 Heart rate; TGCT cis rs4851254 0.961 rs13000759 chr2:100753903 A/T cg23118464 chr2:100721844 AFF3 -0.73 -5.44 -0.44 2.78e-7 Intelligence (multi-trait analysis); TGCT cis rs763121 0.626 rs5750643 chr22:39009017 A/G cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs6977955 1.000 rs11495981 chr7:28177301 A/G cg23620719 chr7:28220237 JAZF1 -0.64 -4.86 -0.4 3.48e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs67478160 0.643 rs2223937 chr14:104286380 A/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs4711350 0.765 rs1318691 chr6:33761884 G/A cg13859433 chr6:33739653 LEMD2 -0.33 -4.97 -0.41 2.18e-6 Schizophrenia; TGCT cis rs35306767 0.855 rs35666723 chr10:867346 A/G cg20503657 chr10:835505 NA 0.77 11.28 0.71 9.73e-21 Eosinophil percentage of granulocytes; TGCT cis rs6424115 0.830 rs2501423 chr1:24199026 A/C cg15997130 chr1:24165203 NA 0.85 9.26 0.64 7.92e-16 Immature fraction of reticulocytes; TGCT cis rs79349575 0.783 rs4294857 chr17:46983391 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs6598955 0.616 rs11247890 chr1:26590182 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs11085466 1.000 rs73552479 chr19:21778816 G/T cg23026602 chr19:21646605 NA -0.53 -4.55 -0.38 1.28e-5 Colorectal or endometrial cancer; TGCT cis rs2688608 0.592 rs10824032 chr10:75528130 G/A cg23231163 chr10:75533350 FUT11 -0.27 -4.68 -0.39 7.45e-6 Inflammatory bowel disease; TGCT cis rs7216064 1.000 rs4790908 chr17:65852907 T/G cg12091567 chr17:66097778 LOC651250 -0.87 -6.75 -0.52 5.12e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1609391 0.543 rs9859810 chr3:136629986 A/G cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs7772486 0.719 rs7753770 chr6:146066161 G/A cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7119 0.717 rs12911854 chr15:77817288 T/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs6684514 1.000 rs6800 chr1:156262653 A/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs3092073 0.617 rs3893276 chr20:44591089 G/C cg23252815 chr20:44420276 WFDC3;DNTTIP1 -0.27 -4.48 -0.37 1.68e-5 Intelligence (multi-trait analysis); TGCT cis rs2033711 0.905 rs893186 chr19:58969179 C/A cg04608855 chr19:58913158 NA 0.58 5.48 0.44 2.29e-7 Uric acid clearance; TGCT cis rs7824557 0.505 rs2736313 chr8:11086942 C/T cg21775007 chr8:11205619 TDH 0.51 4.68 0.39 7.4e-6 Retinal vascular caliber; TGCT cis rs910316 1.000 rs2300601 chr14:75639571 A/G cg11812906 chr14:75593930 NEK9 0.71 7.11 0.54 8.26e-11 Height; TGCT cis rs7666738 0.830 rs10000573 chr4:99048785 G/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6733011 0.500 rs7560696 chr2:99405800 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.65 -0.39 8.2e-6 Bipolar disorder; TGCT cis rs9926296 0.585 rs6500450 chr16:89858024 A/G cg26513180 chr16:89883248 FANCA 1.03 13.79 0.78 8.46e-27 Vitiligo; TGCT cis rs7043114 0.525 rs10761153 chr9:95130769 A/G cg14311495 chr9:95764742 FGD3 -0.22 -4.47 -0.37 1.75e-5 Height; TGCT cis rs4727027 0.933 rs917122 chr7:148848257 T/C cg23583168 chr7:148888333 NA -0.77 -10.06 -0.67 9.29e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs28595532 0.920 rs17323034 chr4:119606518 G/A cg21605333 chr4:119757512 SEC24D 1.33 8.02 0.58 6.93e-13 Cannabis dependence symptom count; TGCT cis rs9914544 1.000 rs6502677 chr17:18803658 A/G cg26378065 chr17:18585709 ZNF286B 0.5 4.45 0.37 1.9e-5 Educational attainment (years of education); TGCT trans rs210152 0.541 rs36003672 chr6:33457816 T/A cg08795360 chr21:41033440 B3GALT5 0.45 7.17 0.54 5.98e-11 Schizophrenia; TGCT cis rs12477438 0.798 rs2123686 chr2:99690135 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT trans rs1814175 0.817 rs4881645 chr11:49791168 G/A cg15704280 chr7:45808275 SEPT13 -0.7 -8.08 -0.59 4.89e-13 Height; TGCT cis rs9486715 0.867 rs11152924 chr6:96877383 A/G cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs9486719 0.843 rs2472875 chr6:96844691 G/A cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs9916302 0.904 rs4795356 chr17:37535631 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs12422267 0.536 rs12303540 chr12:132609679 A/G cg09764611 chr12:132620959 NA 0.37 5.68 0.45 9e-8 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs3749237 0.595 rs4855864 chr3:49521974 C/T cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs9457247 1.000 rs400837 chr6:167411008 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs7100689 0.753 rs1856773 chr10:82060484 T/A cg01528321 chr10:82214614 TSPAN14 0.8 7.9 0.58 1.29e-12 Post bronchodilator FEV1; TGCT cis rs6988636 1.000 rs28600861 chr8:124189063 C/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9911578 1.000 rs8067571 chr17:56868856 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs28687737 chr4:99009226 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4478037 0.822 rs3924696 chr3:33122013 T/C cg19404215 chr3:33155277 CRTAP 0.98 5.13 0.42 1.1e-6 Major depressive disorder; TGCT cis rs2075371 0.932 rs11766132 chr7:133993062 T/C cg11752832 chr7:134001865 SLC35B4 0.67 5.9 0.47 3.17e-8 Mean platelet volume; TGCT cis rs7662987 0.517 rs2851260 chr4:100033574 C/T cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs7666738 0.830 rs114722517 chr4:99042061 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10206020 0.921 rs4072986 chr2:1547734 C/G cg12573674 chr2:1569213 NA -0.49 -4.95 -0.41 2.41e-6 IgG glycosylation; TGCT cis rs7267979 0.866 rs2424698 chr20:25256106 C/T cg03522245 chr20:25566470 NINL 0.62 6.79 0.52 4.07e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11018874 0.532 rs11018867 chr11:89862345 C/T cg14505434 chr11:89522851 NA 0.42 4.68 0.39 7.34e-6 White blood cell types; TGCT cis rs453301 0.571 rs2929454 chr8:9083854 A/C cg15556689 chr8:8085844 FLJ10661 -0.64 -6.05 -0.48 1.6e-8 Joint mobility (Beighton score); TGCT cis rs7513165 1.000 rs11240695 chr1:204158132 C/A cg12731349 chr1:204159619 KISS1 0.52 5.73 0.46 7.09e-8 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs6678914 0.966 rs4950836 chr1:202192624 A/G cg08883485 chr1:201619787 NAV1 -0.39 -4.48 -0.37 1.68e-5 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs2404602 1.000 rs4886818 chr15:76880939 G/A cg22467129 chr15:76604101 ETFA -0.44 -4.86 -0.4 3.41e-6 Blood metabolite levels; TGCT cis rs17221829 0.562 rs10830306 chr11:89366979 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs6867032 0.834 rs10043083 chr5:1995687 C/G cg26168224 chr5:2018326 NA -0.36 -5.54 -0.45 1.69e-7 Gut microbiome composition (winter); TGCT cis rs6433857 0.505 rs16867320 chr2:181362312 A/G cg23363182 chr2:181467187 NA 0.3 4.5 0.37 1.52e-5 Body mass index; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.86 0.4 3.51e-6 Lymphocyte counts; TGCT cis rs9467711 0.606 rs2073529 chr6:26375159 C/T cg10795676 chr6:26370623 BTN3A2 0.46 4.75 0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6089584 0.627 rs35560719 chr20:60561917 A/C cg06108461 chr20:60628389 TAF4 -0.4 -4.8 -0.4 4.4e-6 Body mass index; TGCT cis rs12643440 0.511 rs10489115 chr4:17127327 C/G cg22650099 chr4:17144496 NA 0.53 5.0 0.41 1.87e-6 Metabolite levels (Pyroglutamine); TGCT cis rs13217239 0.646 rs4403259 chr6:26997617 C/T cg05738196 chr6:26577821 NA 0.49 4.75 0.39 5.45e-6 Schizophrenia; TGCT cis rs1691799 0.899 rs1168292 chr12:66732660 C/T cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs9883204 1.000 rs6798189 chr3:123095312 G/A cg04890266 chr3:123102914 ADCY5 0.36 5.11 0.42 1.17e-6 Birth weight; TGCT cis rs17001868 0.568 rs73167007 chr22:40734241 G/C cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs7666738 0.830 rs62318471 chr4:98925848 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.85 0.4 3.59e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6952808 0.626 rs57633152 chr7:2042547 C/G cg14004847 chr7:1930337 MAD1L1 -0.28 -4.46 -0.37 1.79e-5 Bipolar disorder and schizophrenia; TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs7772486 0.641 rs9390374 chr6:146368175 A/T cg13319975 chr6:146136371 FBXO30 -0.67 -6.34 -0.49 3.98e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7208859 0.623 rs8082537 chr17:29015932 T/C cg04154034 chr17:28927549 LRRC37B2 0.8 4.73 0.39 5.94e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs73058052 1.000 rs73058052 chr19:50099422 C/T cg09250473 chr19:50168907 IRF3;BCL2L12 0.81 5.63 0.45 1.15e-7 Fibrinogen levels; TGCT cis rs6430585 0.583 rs730005 chr2:136582694 T/C cg07169764 chr2:136633963 MCM6 1.22 11.84 0.73 4.08e-22 Corneal structure; TGCT cis rs9291683 0.655 rs35750364 chr4:10049049 T/C cg11266682 chr4:10021025 SLC2A9 0.65 9.01 0.63 3.01e-15 Bone mineral density; TGCT cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs35146811 0.657 rs36019559 chr7:99814586 A/G cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg08859206 chr1:53392774 SCP2 -0.47 -7.78 -0.57 2.39e-12 Monocyte count; TGCT cis rs523522 0.926 rs10774555 chr12:120971978 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs28595532 0.920 rs56104443 chr4:119752052 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2289583 0.544 rs12050759 chr15:75265191 G/A cg10253484 chr15:75165896 SCAMP2 0.56 4.99 0.41 2e-6 Systemic lupus erythematosus; TGCT cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg13607699 chr17:42295918 UBTF 0.59 5.38 0.43 3.65e-7 Total body bone mineral density; TGCT cis rs612683 0.658 rs12407689 chr1:100999585 C/G cg06223162 chr1:101003688 GPR88 0.34 5.72 0.46 7.52e-8 Breast cancer; TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs698813 0.604 rs7565928 chr2:44489956 T/C cg00619915 chr2:44497795 NA -0.24 -5.5 -0.44 2.05e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs137699 0.568 rs137682 chr22:39738425 A/C cg11247378 chr22:39784982 NA -0.48 -4.46 -0.37 1.8e-5 IgG glycosylation; TGCT cis rs950169 0.723 rs17589320 chr15:84919996 C/A cg12863693 chr15:85201151 NMB 0.41 4.5 0.38 1.51e-5 Schizophrenia; TGCT cis rs9467773 1.000 rs9467774 chr6:26505036 C/A cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs17376456 1.000 rs34854140 chr5:93538169 G/A cg21475434 chr5:93447410 FAM172A 0.61 4.51 0.38 1.47e-5 Diabetic retinopathy; TGCT cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.55 -5.64 -0.45 1.08e-7 Intelligence (multi-trait analysis); TGCT cis rs12134133 0.888 rs11580394 chr1:207411912 T/C cg02152968 chr1:207494213 CD55 0.6 4.65 0.39 8.43e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs911263 0.603 rs1956529 chr14:68788924 A/G cg18825221 chr14:68749962 RAD51L1 -0.22 -4.46 -0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs2072499 0.966 rs887953 chr1:156191149 T/C cg25208724 chr1:156163844 SLC25A44 1.11 12.8 0.75 1.94e-24 Testicular germ cell tumor; TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg18402987 chr7:1209562 NA 0.4 5.17 0.42 9.17e-7 Longevity;Endometriosis; TGCT cis rs79976124 0.837 rs12201218 chr6:66653619 C/T cg07460842 chr6:66804631 NA -0.57 -5.22 -0.42 7.44e-7 Type 2 diabetes; TGCT cis rs3784262 0.740 rs12910267 chr15:58374603 G/A cg12031962 chr15:58353849 ALDH1A2 -0.48 -6.94 -0.53 1.93e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg13409248 chr3:40428643 ENTPD3 0.56 4.64 0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs7777754 0.512 rs4470989 chr7:50562698 T/A cg18232548 chr7:50535776 DDC -0.38 -5.84 -0.46 4.38e-8 Response to zileuton treatment in asthma (FEV1 change interaction); TGCT cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg17554472 chr22:41940697 POLR3H -0.42 -4.56 -0.38 1.19e-5 Vitiligo; TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg22166914 chr1:53195759 ZYG11B 0.33 5.32 0.43 4.6e-7 Monocyte count; TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg00080972 chr5:178986291 RUFY1 0.56 6.86 0.52 2.95e-10 Lung cancer; TGCT cis rs7674212 0.507 rs223317 chr4:103802824 T/C cg16532752 chr4:104119610 CENPE -0.62 -5.59 -0.45 1.41e-7 Type 2 diabetes; TGCT cis rs2455799 0.586 rs1345161 chr3:15863426 C/T cg12172478 chr3:16357591 RFTN1 0.31 4.74 0.39 5.64e-6 Mean platelet volume; TGCT cis rs11190604 1.000 rs11190578 chr10:102238953 C/T cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9388451 0.874 rs13209968 chr6:126089285 G/C cg10911889 chr6:126070802 HEY2 0.54 5.64 0.45 1.08e-7 Brugada syndrome; TGCT cis rs899997 0.731 rs58717592 chr15:79030417 T/C cg04896959 chr15:78267971 NA -0.37 -5.02 -0.41 1.79e-6 Coronary artery disease or large artery stroke; TGCT cis rs11785400 0.793 rs4736362 chr8:143741381 G/A cg10596483 chr8:143751796 JRK 0.56 5.5 0.44 2.05e-7 Schizophrenia; TGCT trans rs28595532 0.623 rs10016452 chr4:119277490 A/G cg26518628 chr1:97050305 NA -0.6 -7.07 -0.54 1.01e-10 Cannabis dependence symptom count; TGCT cis rs12477438 0.501 rs11683188 chr2:99724512 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs514406 0.505 rs269286 chr1:53169018 C/T cg01802117 chr1:53393560 SCP2 0.45 5.27 0.43 5.74e-7 Monocyte count; TGCT cis rs4268898 0.697 rs6714652 chr2:24383059 C/T cg02683114 chr2:24398427 C2orf84 0.2 4.79 0.4 4.63e-6 Asthma; TGCT cis rs6598955 0.671 rs7417505 chr1:26575523 A/G cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs2980439 0.807 rs2980438 chr8:8094825 T/C cg08975724 chr8:8085496 FLJ10661 0.63 5.94 0.47 2.72e-8 Neuroticism; TGCT cis rs9397585 0.667 rs9479509 chr6:153427265 G/A cg24028809 chr6:153414101 RGS17 0.23 4.92 0.4 2.69e-6 Body mass index; TGCT cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs9611519 0.566 rs4821981 chr22:41415644 A/C cg03806693 chr22:41940476 POLR3H 0.64 6.09 0.48 1.29e-8 Neuroticism; TGCT cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg03517284 chr6:25882590 NA -0.65 -6.72 -0.52 5.87e-10 Blood metabolite levels; TGCT cis rs12497850 0.931 rs9311434 chr3:48884147 T/C cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs11671005 0.735 rs12981649 chr19:58930043 G/C cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg07061783 chr6:25882402 NA -0.6 -5.59 -0.45 1.35e-7 Intelligence (multi-trait analysis); TGCT cis rs2486012 0.737 rs2906465 chr1:44323736 T/C cg12908607 chr1:44402522 ARTN -0.72 -5.68 -0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs4253772 0.550 rs6008615 chr22:46707928 G/A cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs6424115 0.830 rs2502993 chr1:24201262 A/G cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs6785206 0.614 rs73198879 chr3:128542368 T/G cg25356066 chr3:128598488 ACAD9 -0.91 -4.79 -0.4 4.69e-6 Lymphocyte percentage of white cells; TGCT cis rs4285028 0.747 rs1128163 chr3:121350573 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.93 -7.34 -0.55 2.49e-11 Multiple sclerosis; TGCT cis rs2050392 0.929 rs10826798 chr10:30700904 G/A cg13289132 chr10:30722225 MAP3K8 0.36 4.47 0.37 1.72e-5 Inflammatory bowel disease; TGCT cis rs9916302 0.904 rs13341996 chr17:37536862 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs2839186 0.560 rs9975345 chr21:47843004 T/C cg25737836 chr21:47705150 C21orf57;MCM3AP 0.2 4.55 0.38 1.28e-5 Testicular germ cell tumor; TGCT cis rs13396424 0.639 rs2711302 chr2:46220888 A/G cg04380228 chr2:47142555 MCFD2 0.7 4.76 0.39 5.38e-6 Metabolite levels (X-11787); TGCT cis rs11190604 1.000 rs10786596 chr10:102282126 C/A cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.72e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7617773 0.563 rs13082269 chr3:48392274 G/A cg11946769 chr3:48343235 NME6 0.59 4.91 0.4 2.83e-6 Coronary artery disease; TGCT cis rs7586879 0.616 rs10206196 chr2:25137323 T/C cg01884057 chr2:25150051 NA 0.35 6.84 0.52 3.21e-10 Body mass index; TGCT cis rs28595532 0.748 rs55949457 chr4:119336174 A/G cg21605333 chr4:119757512 SEC24D 0.85 5.43 0.44 2.84e-7 Cannabis dependence symptom count; TGCT cis rs28595532 0.920 rs116401323 chr4:119721727 C/T cg14228332 chr4:119757509 SEC24D 1.38 6.91 0.53 2.21e-10 Cannabis dependence symptom count; TGCT cis rs3733585 0.699 rs4588456 chr4:9963895 A/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs908922 0.887 rs7535188 chr1:152475899 G/A cg20991723 chr1:152506922 NA 0.47 6.38 0.5 3.23e-9 Hair morphology; TGCT cis rs28785552 0.536 rs7246050 chr19:53248632 T/C cg10871876 chr19:53194124 ZNF83 0.47 5.9 0.47 3.24e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs3733585 0.577 rs5014939 chr4:9953253 T/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.46 -0.5 2.12e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg08859206 chr1:53392774 SCP2 -0.41 -6.12 -0.48 1.12e-8 Monocyte count; TGCT cis rs4319547 0.741 rs4758663 chr12:122939483 A/G cg23029597 chr12:123009494 RSRC2 -0.27 -4.44 -0.37 1.99e-5 Body mass index; TGCT cis rs3849570 0.695 rs9830445 chr3:81508063 T/G cg07356753 chr3:81810745 GBE1 0.57 4.72 0.39 6.25e-6 Waist circumference;Body mass index; TGCT cis rs3772130 1.000 rs3772128 chr3:121345094 G/T cg01951420 chr3:121553821 IQCB1;EAF2 0.55 4.95 0.41 2.32e-6 Cognitive performance; TGCT cis rs7954584 0.567 rs11043243 chr12:122356370 G/C cg21016266 chr12:122356598 WDR66 0.53 6.61 0.51 1.04e-9 Mean corpuscular volume; TGCT cis rs11105298 0.891 rs6538189 chr12:89885923 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs67460515 0.892 rs13059340 chr3:161062631 T/C cg03342759 chr3:160939853 NMD3 -0.51 -5.49 -0.44 2.14e-7 Parkinson's disease; TGCT cis rs7666738 0.791 rs1830231 chr4:99026185 A/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7586879 0.521 rs7597332 chr2:25075675 A/G cg01884057 chr2:25150051 NA 0.3 5.61 0.45 1.26e-7 Body mass index; TGCT cis rs1878931 0.507 rs67218524 chr16:3403057 G/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -5.22 -0.42 7.21e-7 Body mass index (adult); TGCT cis rs3020736 0.500 rs1801311 chr22:42486723 G/A cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg23205692 chr1:25664452 TMEM50A 0.52 5.34 0.43 4.2e-7 Erythrocyte sedimentation rate; TGCT cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg22105103 chr4:187893119 NA 0.35 5.08 0.41 1.38e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9393777 0.513 rs3999471 chr6:26650306 T/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs9308731 0.842 rs56173510 chr2:111928436 G/T cg04202892 chr2:111875749 ACOXL 0.45 4.94 0.41 2.44e-6 Chronic lymphocytic leukemia; TGCT cis rs1997103 1.000 rs2331067 chr7:55408232 A/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7829975 0.509 rs7838674 chr8:8797073 A/T cg15556689 chr8:8085844 FLJ10661 -0.69 -6.14 -0.48 1.01e-8 Mood instability; TGCT cis rs6688613 0.759 rs61815132 chr1:166920911 A/G cg07049167 chr1:166818506 POGK 0.25 5.23 0.42 7.11e-7 Refractive astigmatism; TGCT cis rs986417 0.818 rs8014133 chr14:61104738 A/G cg27398547 chr14:60952738 C14orf39 1.45 9.82 0.66 3.5e-17 Gut microbiota (bacterial taxa); TGCT cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg11890956 chr21:40555474 PSMG1 -0.73 -6.98 -0.53 1.59e-10 Menarche (age at onset); TGCT cis rs916888 0.821 rs199525 chr17:44847834 T/G cg15921436 chr17:44337874 NA 0.53 7.54 0.56 8.43e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs1814175 0.791 rs11040472 chr11:49703116 C/T cg11707556 chr5:10655725 ANKRD33B -0.38 -7.6 -0.56 6.14e-12 Height; TGCT cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg06481639 chr22:41940642 POLR3H -0.74 -6.51 -0.5 1.71e-9 Vitiligo; TGCT cis rs9913156 0.517 rs11868227 chr17:4614539 G/A cg19197139 chr17:4613644 ARRB2 0.63 5.81 0.46 4.96e-8 Lymphocyte counts; TGCT cis rs6988636 1.000 rs10096350 chr8:124184470 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9303401 0.659 rs11079358 chr17:56920949 G/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs1729951 0.575 rs747842 chr3:136703121 A/C cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs6542838 0.611 rs6742047 chr2:99531460 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.27 -0.43 5.77e-7 Fear of minor pain; TGCT cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs654950 0.934 rs662999 chr1:42001160 A/C cg06885757 chr1:42089581 HIVEP3 0.28 4.53 0.38 1.35e-5 Airway imaging phenotypes; TGCT cis rs9811920 0.609 rs793501 chr3:99591638 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.58 -6.55 -0.51 1.35e-9 Axial length; TGCT cis rs7666738 0.830 rs10021044 chr4:99002488 A/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs56235845 0.694 rs11748912 chr5:176765395 G/A cg17509989 chr5:176798049 RGS14 0.55 7.58 0.56 6.89e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs4851254 0.961 rs6713524 chr2:100747357 A/G cg04109781 chr2:100722022 AFF3 0.42 4.5 0.37 1.53e-5 Intelligence (multi-trait analysis); TGCT cis rs2688608 0.592 rs12253482 chr10:75496130 G/A cg19442545 chr10:75533431 FUT11 -0.37 -5.82 -0.46 4.69e-8 Inflammatory bowel disease; TGCT trans rs17684571 0.938 rs35619924 chr6:56560666 T/C cg14229071 chr15:89282588 NA 0.51 6.79 0.52 4.04e-10 Schizophrenia; TGCT cis rs9399135 0.967 rs4896123 chr6:135295410 T/G cg24558204 chr6:135376177 HBS1L 0.48 4.79 0.39 4.76e-6 Red blood cell count; TGCT trans rs57221529 0.766 rs72703075 chr5:592819 C/T cg11887960 chr12:57824829 NA 1.2 9.53 0.65 1.75e-16 Lung disease severity in cystic fibrosis; TGCT cis rs7100689 0.646 rs10788562 chr10:82072310 C/T cg01528321 chr10:82214614 TSPAN14 -0.75 -7.56 -0.56 7.74e-12 Post bronchodilator FEV1; TGCT cis rs765787 0.530 rs11636367 chr15:45535862 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs2153535 0.580 rs1932276 chr6:8442593 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs11644362 1.000 rs976243 chr16:12991679 A/T cg06890432 chr16:12997467 SHISA9 -0.6 -6.73 -0.52 5.59e-10 Positive affect;Subjective well-being; TGCT cis rs1008375 0.544 rs56227066 chr4:17565713 G/A cg16339924 chr4:17578868 LAP3 0.57 4.84 0.4 3.71e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg10819733 chr22:24237672 NA -0.28 -4.59 -0.38 1.09e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9296092 0.560 rs9469502 chr6:33526648 G/A cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs1862618 0.671 rs2591961 chr5:56238597 A/G cg20203395 chr5:56204925 C5orf35 0.55 5.18 0.42 8.85e-7 Initial pursuit acceleration; TGCT cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg09904177 chr6:26538194 HMGN4 0.68 6.27 0.49 5.41e-9 Intelligence (multi-trait analysis); TGCT cis rs6032067 0.673 rs13039345 chr20:43895932 G/C cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -6.75 -0.52 4.97e-10 Blood protein levels; TGCT cis rs12477438 0.765 rs9710648 chr2:99673129 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs950776 0.752 rs62010327 chr15:78892784 G/A cg06917634 chr15:78832804 PSMA4 0.65 5.07 0.41 1.41e-6 Sudden cardiac arrest; TGCT cis rs9296092 0.517 rs62405949 chr6:33522800 G/A cg13560919 chr6:33536144 NA -0.2 -4.64 -0.38 8.68e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs350251 0.868 rs350232 chr16:12190947 G/C cg01574788 chr16:12184133 SNX29 0.41 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs4815426 chr20:25405186 A/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs8073060 0.785 rs11659054 chr17:33867678 C/T cg19694781 chr19:47549865 TMEM160 0.45 8.13 0.59 3.84e-13 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs8077577 0.848 rs12600694 chr17:18091019 C/T cg09161412 chr17:18057145 MYO15A -0.6 -4.99 -0.41 2.02e-6 Obesity-related traits; TGCT cis rs9807989 0.801 rs6734742 chr2:102967857 C/T cg09003973 chr2:102972529 NA 0.69 6.22 0.49 6.84e-9 Asthma; TGCT cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg03264133 chr6:25882463 NA 0.67 6.3 0.49 4.73e-9 Intelligence (multi-trait analysis); TGCT cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg26531700 chr6:26746687 NA -0.57 -5.21 -0.42 7.62e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs208515 0.525 rs10944868 chr6:66687508 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.92 10.09 0.67 7.45e-18 Exhaled nitric oxide levels; TGCT cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg03806693 chr22:41940476 POLR3H 1.15 13.16 0.76 2.69e-25 Vitiligo; TGCT cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.47 -4.54 -0.38 1.32e-5 Prudent dietary pattern; TGCT cis rs6460942 1.000 rs117657017 chr7:12318891 T/C cg06484146 chr7:12443880 VWDE -0.55 -4.56 -0.38 1.22e-5 Coronary artery disease; TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg25767906 chr1:53392781 SCP2 -0.61 -7.41 -0.55 1.74e-11 Monocyte count; TGCT cis rs4919669 0.668 rs10883740 chr10:104334822 A/C cg05855489 chr10:104503620 C10orf26 0.7 4.44 0.37 1.94e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs11190604 0.767 rs35508946 chr10:102191156 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.79 0.4 4.69e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11098499 0.874 rs6822498 chr4:120120183 T/C cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs6912958 0.535 rs242283 chr6:88030931 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.76 0.46 6.31e-8 Monocyte percentage of white cells; TGCT cis rs4689388 0.926 rs10937717 chr4:6295087 T/A cg00701064 chr4:6280414 WFS1 0.39 4.92 0.4 2.72e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1008375 1.000 rs2159584 chr4:17620568 G/A cg18681998 chr4:17616180 MED28 1.01 11.3 0.71 8.54e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs651907 0.557 rs36002990 chr3:101437862 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.21 0.68 3.89e-18 Colorectal cancer; TGCT cis rs7917772 0.582 rs7899004 chr10:104341435 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.56 -5.47 -0.44 2.4e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2729354 0.953 rs2649663 chr11:57357305 C/T cg24343310 chr11:57249947 NA 0.28 4.89 0.4 3.04e-6 Blood protein levels; TGCT cis rs7582180 0.614 rs1030901 chr2:101007314 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.81 0.4 4.21e-6 Intelligence (multi-trait analysis); TGCT cis rs1008375 1.000 rs10019856 chr4:17615742 T/A cg16339924 chr4:17578868 LAP3 0.74 6.0 0.47 2.02e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs13217239 0.646 rs12209886 chr6:26984757 G/A cg26531700 chr6:26746687 NA 0.68 6.79 0.52 4.1e-10 Schizophrenia; TGCT cis rs858239 0.669 rs6461688 chr7:23116615 G/A cg05602783 chr7:23145260 KLHL7 -0.63 -5.39 -0.44 3.47e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs7552404 1.000 rs1498312 chr1:76177849 C/T cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9468186 1 rs9468186 chr6:27626631 A/G cg26587870 chr6:27730563 NA -0.26 -4.48 -0.37 1.69e-5 Neuroticism; TGCT cis rs6450176 0.904 rs4351101 chr5:53300591 G/A ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs6671200 1.000 rs259354 chr1:95718205 T/C cg26537280 chr1:95699037 RWDD3 -0.7 -5.55 -0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs7428 0.527 rs7607284 chr2:85547376 C/G cg03728395 chr2:85555865 TGOLN2 -0.31 -5.17 -0.42 9.27e-7 Ear protrusion; TGCT cis rs736408 0.716 rs2300149 chr3:52822921 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.03 0.48 1.72e-8 Bipolar disorder; TGCT cis rs7085104 0.700 rs6163 chr10:104596924 C/A cg04362960 chr10:104952993 NT5C2 0.57 5.05 0.41 1.54e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg14827481 chr10:134361889 INPP5A -0.29 -4.69 -0.39 7.09e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs950027 1.000 rs950027 chr15:45801035 C/T cg26924012 chr15:45694286 SPATA5L1 -0.47 -5.04 -0.41 1.6e-6 Response to fenofibrate (adiponectin levels); TGCT cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg03452623 chr4:187889614 NA -0.34 -4.94 -0.41 2.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9443645 0.901 rs9448588 chr6:79590061 T/G cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs7474896 0.537 rs1022449 chr10:38279467 T/A cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs9948 0.786 rs62152765 chr2:97440420 G/A cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs6728642 1.000 rs113934577 chr2:97888047 G/A cg26665480 chr2:98280029 ACTR1B -0.97 -4.85 -0.4 3.69e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs17152411 1.000 rs7077936 chr10:126650065 C/T cg07906193 chr10:126599966 NA 0.37 4.64 0.38 8.78e-6 Height; TGCT cis rs11650494 0.710 rs11654557 chr17:47390136 A/G cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs57590327 0.504 rs13065281 chr3:81693550 G/A cg07356753 chr3:81810745 GBE1 -0.76 -6.9 -0.53 2.43e-10 Extraversion; TGCT cis rs6977660 0.714 rs1468287 chr7:19784210 T/A cg07541023 chr7:19748670 TWISTNB 0.83 4.69 0.39 7.01e-6 Thyroid stimulating hormone; TGCT cis rs9914544 0.545 rs8069826 chr17:18765490 G/T cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs1371867 0.846 rs1788197 chr8:101290928 T/C cg00191853 chr8:101177733 SPAG1 -0.23 -4.8 -0.4 4.44e-6 Atrioventricular conduction; TGCT cis rs11578119 0.866 rs12132288 chr1:170366441 A/G cg09767346 chr1:170501363 GORAB 0.63 4.82 0.4 4.09e-6 Male-pattern baldness; TGCT cis rs42648 0.869 rs12374728 chr7:89941884 T/C cg25739043 chr7:89950458 NA -0.73 -7.31 -0.55 2.83e-11 Homocysteine levels; TGCT cis rs6582630 0.555 rs2090785 chr12:38424342 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.7 0.57 3.77e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs727505 0.954 rs59379598 chr7:124596903 C/G cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs6570726 0.577 rs399502 chr6:145805874 A/G cg23711669 chr6:146136114 FBXO30 0.71 6.52 0.51 1.62e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs3766606 0.505 rs60057745 chr1:7946819 G/A cg26816564 chr1:7831052 VAMP3 0.64 4.98 0.41 2.05e-6 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; TGCT cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.66 -0.39 8.17e-6 Initial pursuit acceleration; TGCT cis rs736408 0.812 rs746694 chr3:52826620 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.54 4.92 0.4 2.72e-6 Bipolar disorder; TGCT cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs5750830 0.594 rs9611169 chr22:39783027 C/T cg05872129 chr22:39784769 NA -0.86 -9.51 -0.65 1.92e-16 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.829 rs12636030 chr3:49182237 A/G cg18654377 chr3:49208889 KLHDC8B -0.38 -4.81 -0.4 4.25e-6 Parkinson's disease; TGCT cis rs3749237 0.595 rs7621003 chr3:49411404 T/C cg02487422 chr3:49467188 NICN1 0.59 6.01 0.47 1.92e-8 Resting heart rate; TGCT cis rs881375 1.000 rs10760121 chr9:123647915 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.38 4.45 0.37 1.92e-5 Rheumatoid arthritis; TGCT trans rs28595532 0.748 rs113336496 chr4:119336957 C/T cg26518628 chr1:97050305 NA -0.56 -6.79 -0.52 4.19e-10 Cannabis dependence symptom count; TGCT cis rs2836974 0.799 rs13047550 chr21:40515495 T/C cg06238570 chr21:40685208 BRWD1 0.59 5.1 0.42 1.23e-6 Cognitive function; TGCT cis rs3749237 0.964 rs35210174 chr3:49812606 C/T cg07636037 chr3:49044803 WDR6 0.64 5.63 0.45 1.13e-7 Resting heart rate; TGCT trans rs9951602 0.512 rs8089247 chr18:76651467 C/A cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs453301 0.686 rs7017868 chr8:8873293 G/A cg11995313 chr8:8860691 ERI1 0.51 4.46 0.37 1.84e-5 Joint mobility (Beighton score); TGCT cis rs9467711 0.516 rs1165163 chr6:25863487 G/C cg03517284 chr6:25882590 NA -0.73 -4.85 -0.4 3.62e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7258465 0.931 rs271629 chr19:18623198 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs3806843 0.576 rs246063 chr5:140324492 T/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7937682 0.602 rs503905 chr11:111390762 G/C cg09085632 chr11:111637200 PPP2R1B -0.67 -6.3 -0.49 4.63e-9 Primary sclerosing cholangitis; TGCT cis rs2115630 0.653 rs61394864 chr15:85170174 T/C cg12863693 chr15:85201151 NMB -0.4 -5.46 -0.44 2.47e-7 P wave terminal force; TGCT cis rs11190604 1.000 rs35106985 chr10:102307542 T/C cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.48e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9303401 0.659 rs34556735 chr17:56694447 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs4711350 0.911 rs9461907 chr6:33726990 A/C cg18005901 chr6:33739558 LEMD2 -0.46 -4.96 -0.41 2.27e-6 Schizophrenia; TGCT cis rs10493773 0.894 rs12067749 chr1:86197922 T/C cg17807903 chr1:86174739 ZNHIT6 -0.42 -5.58 -0.45 1.46e-7 Urate levels in overweight individuals; TGCT cis rs587847 0.737 rs1520950 chr15:37667807 C/T cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs2251381 0.722 rs2251278 chr21:30529234 A/G cg24692254 chr21:30365293 RNF160 0.76 7.08 0.54 9.5e-11 Selective IgA deficiency; TGCT cis rs7666738 0.830 rs13133619 chr4:99067312 C/G cg17366294 chr4:99064904 C4orf37 -0.7 -7.08 -0.54 9.29e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs651907 0.535 rs35810977 chr3:101531380 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.82 0.4 4.05e-6 Colorectal cancer; TGCT cis rs28595532 0.920 rs114683212 chr4:119760209 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs4733781 0.509 rs1158569 chr8:131331012 A/C cg16277922 chr8:131349729 ASAP1 0.53 8.77 0.62 1.15e-14 Tuberculosis; TGCT cis rs2692947 0.655 rs60090597 chr2:96406266 G/A cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10782582 0.609 rs78556436 chr1:76352875 G/A cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs1008375 0.966 rs2872957 chr4:17651757 C/A cg16339924 chr4:17578868 LAP3 0.67 5.55 0.45 1.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs651907 0.557 rs34947019 chr3:101532235 C/T cg12386194 chr3:101231763 SENP7 0.45 4.45 0.37 1.87e-5 Colorectal cancer; TGCT cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg08280861 chr8:58055591 NA 0.49 5.26 0.43 6.19e-7 Developmental language disorder (linguistic errors); TGCT cis rs11098499 0.863 rs59732491 chr4:120489588 G/C cg09307838 chr4:120376055 NA 0.68 6.47 0.5 2.02e-9 Corneal astigmatism; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs7178572 0.568 rs62008452 chr15:77591007 A/G cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT trans rs214785 0.790 rs6075877 chr20:2261782 A/G cg24980040 chr10:1714535 ADARB2 0.45 6.75 0.52 4.95e-10 Basal cell carcinoma; TGCT cis rs2404602 0.716 rs12440815 chr15:76627328 C/A cg22467129 chr15:76604101 ETFA -0.6 -7.44 -0.56 1.45e-11 Blood metabolite levels; TGCT cis rs739496 0.615 rs640783 chr12:112168050 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs9527 0.640 rs6584541 chr10:104929124 A/G cg04362960 chr10:104952993 NT5C2 0.65 5.59 0.45 1.36e-7 Arsenic metabolism; TGCT cis rs7662987 0.517 rs2602877 chr4:100039847 T/A cg12011299 chr4:100065546 ADH4 0.42 4.94 0.41 2.44e-6 Smoking initiation; TGCT cis rs6952808 0.601 rs3800882 chr7:2120758 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.64 -0.45 1.1e-7 Bipolar disorder and schizophrenia; TGCT cis rs12477438 0.508 rs2516832 chr2:99771268 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs4906332 1.000 rs12892062 chr14:103883512 A/G cg26031613 chr14:104095156 KLC1 -0.51 -4.63 -0.38 9.17e-6 Coronary artery disease; TGCT cis rs11252926 0.574 rs7068976 chr10:453112 A/G cg18196295 chr10:418757 DIP2C 0.29 4.73 0.39 5.91e-6 Psychosis in Alzheimer's disease; TGCT cis rs10504229 0.861 rs60346509 chr8:58196050 G/T cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs12711979 0.509 rs13005405 chr2:3826324 C/T cg17052675 chr2:3827356 NA -0.55 -12.72 -0.75 3.04e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs3733585 0.624 rs7376154 chr4:9952587 C/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.65 -0.57 4.78e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10791097 0.720 rs6590516 chr11:130733393 G/T cg05962950 chr11:130786565 SNX19 0.89 11.06 0.7 3.3e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3796352 0.892 rs35076015 chr3:53026366 C/T cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4730250 0.554 rs17428504 chr7:106914944 T/C cg02696742 chr7:106810147 HBP1 -0.72 -5.29 -0.43 5.34e-7 Osteoarthritis; TGCT cis rs10779751 0.881 rs2744815 chr1:11360957 C/T cg08854313 chr1:11322531 MTOR 0.77 8.73 0.62 1.45e-14 Body mass index; TGCT cis rs6087990 0.735 rs6058892 chr20:31388461 C/T cg13636640 chr20:31349939 DNMT3B 0.97 12.84 0.76 1.63e-24 Ulcerative colitis; TGCT cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg03264133 chr6:25882463 NA -0.52 -5.38 -0.44 3.53e-7 Blood metabolite levels; TGCT cis rs7607369 0.637 rs17462630 chr2:219286541 C/G cg02176678 chr2:219576539 TTLL4 -0.5 -6.57 -0.51 1.27e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs9372253 0.678 rs6568644 chr6:110707820 C/T cg00083206 chr6:110721305 DDO -0.36 -5.22 -0.42 7.2e-7 Platelet distribution width; TGCT cis rs2180341 0.960 rs7753913 chr6:127671296 A/G cg24812749 chr6:127587940 RNF146 1.01 7.62 0.56 5.59e-12 Breast cancer; TGCT cis rs11626933 1.000 rs3742669 chr14:90767746 C/A cg14092571 chr14:90743983 NA 0.31 6.54 0.51 1.42e-9 Gut microbiota (bacterial taxa); TGCT cis rs6461049 0.765 rs1476887 chr7:2151633 T/C cg22963979 chr7:1858916 MAD1L1 -0.42 -6.64 -0.51 9.01e-10 Schizophrenia; TGCT cis rs12950390 0.893 rs11079789 chr17:45849715 A/G cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.6e-6 IgG glycosylation; TGCT cis rs877529 0.625 rs713841 chr22:39529029 A/G cg18708252 chr22:39545030 CBX7 -0.36 -5.18 -0.42 8.55e-7 Multiple myeloma; TGCT cis rs9985766 0.958 rs7659009 chr4:150992596 T/C cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs61931739 0.517 rs12815556 chr12:34319670 G/A cg06521331 chr12:34319734 NA -0.3 -4.45 -0.37 1.87e-5 Morning vs. evening chronotype; TGCT cis rs8180040 1.000 rs807810 chr3:47403892 G/A cg27129171 chr3:47204927 SETD2 -0.7 -8.88 -0.62 6.43e-15 Colorectal cancer; TGCT cis rs7267979 0.780 rs6050679 chr20:25537827 A/T cg16686733 chr20:25566563 NINL 0.53 5.17 0.42 9.02e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1348850 0.793 rs6734528 chr2:178493731 G/A cg22681709 chr2:178499509 PDE11A -0.47 -5.67 -0.45 9.41e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs6901250 0.851 rs9374624 chr6:117145837 A/C cg12892004 chr6:117198278 RFX6 0.55 6.79 0.52 4.21e-10 C-reactive protein levels; TGCT cis rs6951245 0.507 rs11976805 chr7:1138716 C/T cg03188948 chr7:1209495 NA 0.5 5.32 0.43 4.65e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs916888 0.773 rs199457 chr17:44795469 C/T cg22433210 chr17:43662623 NA 1.06 7.46 0.56 1.32e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs79149102 0.579 rs73438569 chr15:75354486 T/A cg09165964 chr15:75287851 SCAMP5 -1.15 -6.31 -0.49 4.4e-9 Lung cancer; TGCT cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.63 6.66 0.51 8.14e-10 Height; TGCT cis rs7552404 1.000 rs942270 chr1:76177332 G/A cg03433033 chr1:76189801 ACADM 0.82 9.72 0.66 6.06e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg04389838 chr3:44770851 ZNF501 -0.37 -4.76 -0.39 5.25e-6 Depressive symptoms; TGCT cis rs9436747 0.667 rs12033452 chr1:66038435 C/A cg14976592 chr1:65886160 LEPROT;LEPR 0.55 5.18 0.42 8.81e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT trans rs4332037 0.539 rs62444881 chr7:2052318 C/T cg10840412 chr1:235813424 GNG4 0.97 6.99 0.53 1.47e-10 Bipolar disorder; TGCT cis rs77741769 0.571 rs12831094 chr12:121292704 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.58e-5 Mean corpuscular volume; TGCT trans rs2624839 0.704 rs2624833 chr3:50212512 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.81 7.08 0.54 9.41e-11 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.561 rs2084988 chr2:99655755 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs11085466 1.000 rs2292986 chr19:21776332 A/C cg02997983 chr19:21646781 NA 0.6 4.74 0.39 5.72e-6 Colorectal or endometrial cancer; TGCT cis rs7666738 0.830 rs17550735 chr4:99014076 T/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9549260 0.564 rs4943804 chr13:41269994 A/G cg21288729 chr13:41239152 FOXO1 0.94 9.15 0.63 1.47e-15 Red blood cell count; TGCT cis rs910316 1.000 rs876403 chr14:75602834 A/T cg23033748 chr14:75592666 NEK9 0.29 4.93 0.4 2.61e-6 Height; TGCT cis rs651907 0.557 rs3806654 chr3:101396529 G/C cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.08 -0.54 9.37e-11 Colorectal cancer; TGCT cis rs2948294 0.566 rs13274039 chr8:8111659 A/G cg15556689 chr8:8085844 FLJ10661 0.76 6.22 0.49 6.92e-9 Red cell distribution width; TGCT cis rs617219 0.710 rs2607142 chr5:78557948 T/C cg23514016 chr5:78407564 BHMT 0.32 4.87 0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7937682 1.000 rs505372 chr11:111507189 A/C cg09085632 chr11:111637200 PPP2R1B -1.02 -9.92 -0.67 1.98e-17 Primary sclerosing cholangitis; TGCT cis rs1997103 0.863 rs2140916 chr7:55403154 A/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs35146811 0.586 rs12666107 chr7:99778019 G/C cg22906224 chr7:99728672 NA 0.52 4.55 0.38 1.24e-5 Coronary artery disease; TGCT cis rs377070 0.816 rs309416 chr4:123621916 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.44 4.85 0.4 3.6e-6 Mosquito bite size; TGCT cis rs933688 1.000 rs2059207 chr5:90731931 C/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 9.89 0.66 2.31e-17 Smoking behavior; TGCT cis rs17750015 0.733 rs7506986 chr18:54404558 C/T cg18434998 chr18:54306185 TXNL1 -0.53 -5.18 -0.42 8.85e-7 Depression and alcohol dependence; TGCT cis rs9527 0.668 rs7092815 chr10:104736345 G/T cg04362960 chr10:104952993 NT5C2 0.66 5.45 0.44 2.58e-7 Arsenic metabolism; TGCT cis rs7666738 0.830 rs11941844 chr4:99042722 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6840360 0.571 rs4696276 chr4:152532682 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs9381040 0.610 rs6940462 chr6:41020223 G/A cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT trans rs1005277 0.505 rs200936 chr10:38134935 T/C cg17830980 chr10:43048298 ZNF37B -0.72 -8.22 -0.59 2.27e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4776059 0.916 rs2414161 chr15:52883285 T/C cg25063058 chr15:52860530 ARPP19 0.53 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs617219 0.671 rs12189188 chr5:78552312 C/T cg09550809 chr5:78407562 BHMT 0.4 5.49 0.44 2.19e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9467711 1.000 rs6939978 chr6:26328462 G/C cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7914558 0.966 rs11191518 chr10:104782853 C/G cg15744005 chr10:104629667 AS3MT -0.38 -4.69 -0.39 7.04e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7568458 0.709 rs11895399 chr2:85753806 C/A cg02493740 chr2:85810744 VAMP5 -0.29 -5.7 -0.46 8.09e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9322193 0.884 rs10872647 chr6:150079823 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.46e-5 Lung cancer; TGCT cis rs7614311 0.681 rs6809100 chr3:63901180 A/G cg22134162 chr3:63841271 THOC7 -0.4 -5.19 -0.42 8.38e-7 Lung function (FVC);Lung function (FEV1); TGCT trans rs3780486 0.846 rs6476402 chr9:33148552 G/A cg20290983 chr6:43655470 MRPS18A 1.14 14.03 0.78 2.25e-27 IgG glycosylation; TGCT cis rs10832963 1.000 rs4757676 chr11:18640477 C/T cg09201001 chr11:18656081 SPTY2D1 1.05 11.63 0.72 1.34e-21 Breast cancer; TGCT cis rs4664308 0.875 rs2124969 chr2:160989486 T/C cg03641300 chr2:160917029 PLA2R1 -0.27 -6.79 -0.52 4.08e-10 Idiopathic membranous nephropathy; TGCT cis rs6840360 0.642 rs11726254 chr4:152438850 G/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs9650657 0.615 rs11986845 chr8:10691318 T/C cg16664915 chr8:10907788 XKR6 -0.29 -4.51 -0.38 1.5e-5 Neuroticism; TGCT cis rs11098499 0.863 rs7695620 chr4:120452776 G/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs9985766 0.958 rs76947074 chr4:150996295 G/A cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs12681287 0.752 rs13255058 chr8:87287445 G/A cg27223183 chr8:87520930 FAM82B -0.82 -5.86 -0.47 3.98e-8 Caudate activity during reward; TGCT trans rs2469997 1.000 rs2470003 chr8:120357482 C/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs6558530 0.666 rs11136422 chr8:1695909 T/C cg09410841 chr8:1729607 CLN8 0.67 6.0 0.47 2.05e-8 Systolic blood pressure; TGCT cis rs2197308 0.634 rs11173475 chr12:38086665 G/C cg26384229 chr12:38710491 ALG10B 0.63 5.62 0.45 1.2e-7 Morning vs. evening chronotype; TGCT cis rs4851266 1.000 rs4851268 chr2:100825864 C/T cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs2463822 0.844 rs7104149 chr11:62171627 A/G cg06239285 chr11:62104954 ASRGL1 -0.79 -5.22 -0.42 7.43e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9325144 0.555 rs4882279 chr12:38688918 C/A cg26384229 chr12:38710491 ALG10B 0.66 6.12 0.48 1.11e-8 Morning vs. evening chronotype; TGCT cis rs3820068 0.580 rs61169376 chr1:16003832 A/G cg05660106 chr1:15850417 CASP9 0.66 5.93 0.47 2.8e-8 Systolic blood pressure; TGCT cis rs700651 0.821 rs700690 chr2:198727626 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial aneurysm; TGCT cis rs9388451 0.839 rs3799709 chr6:126078361 A/G cg10911889 chr6:126070802 HEY2 0.53 5.52 0.44 1.88e-7 Brugada syndrome; TGCT cis rs2486288 0.656 rs12915314 chr15:45551491 C/G cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs74233809 0.786 rs11191564 chr10:104878543 C/T cg05855489 chr10:104503620 C10orf26 0.82 4.44 0.37 1.97e-5 Birth weight; TGCT cis rs9611565 0.559 rs132765 chr22:42008068 A/G cg17554472 chr22:41940697 POLR3H 0.5 5.35 0.43 4.07e-7 Vitiligo; TGCT cis rs2982552 0.873 rs1999805 chr6:152068364 G/A cg22157087 chr6:152012887 ESR1 0.2 4.77 0.39 5e-6 Bone properties (heel); TGCT cis rs875971 0.660 rs10950044 chr7:66042976 A/G cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs9362426 0.608 rs6940716 chr6:88142979 A/G cg10919329 chr6:88182879 SLC35A1 -0.6 -4.52 -0.38 1.4e-5 Depressive episodes in bipolar disorder; TGCT cis rs7666738 0.830 rs7673385 chr4:99024922 T/G cg17366294 chr4:99064904 C4orf37 0.72 7.54 0.56 8.52e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs1929523 chr6:146339989 T/A cg05347473 chr6:146136440 FBXO30 0.56 5.29 0.43 5.34e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs909002 0.772 rs12740754 chr1:32083273 G/C cg11573219 chr1:32083031 HCRTR1 -0.45 -5.86 -0.47 3.83e-8 Intelligence (multi-trait analysis); TGCT cis rs394563 0.559 rs13219868 chr6:149686518 T/G cg11245181 chr6:149772854 ZC3H12D 0.28 4.48 0.37 1.7e-5 Dupuytren's disease; TGCT cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg11644478 chr21:40555479 PSMG1 -0.64 -5.91 -0.47 3.02e-8 Cognitive function; TGCT cis rs2455799 0.613 rs11128762 chr3:15883439 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.73 -0.39 6.09e-6 Mean platelet volume; TGCT trans rs1973993 0.691 rs2985636 chr1:96889884 T/A cg10631902 chr5:14652156 NA 0.4 10.91 0.7 7.68e-20 Weight; TGCT cis rs28595532 0.920 rs114611353 chr4:119736607 C/T cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs1322512 1.000 rs1744369 chr6:152946531 T/A cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs1005277 0.579 rs176838 chr10:38371899 A/T cg25427524 chr10:38739819 LOC399744 0.4 7.63 0.57 5.31e-12 Extrinsic epigenetic age acceleration; TGCT cis rs17401966 1.000 rs2229687 chr1:10473196 C/T cg19773385 chr1:10388646 KIF1B -0.23 -5.42 -0.44 2.97e-7 Hepatocellular carcinoma; TGCT cis rs7731657 0.537 rs112876284 chr5:130293884 G/C cg08523029 chr5:130500466 HINT1 -0.58 -4.84 -0.4 3.8e-6 Fasting plasma glucose; TGCT cis rs9297145 0.678 rs62473007 chr7:98749598 G/C cg05967295 chr7:98741636 SMURF1 1.01 12.87 0.76 1.33e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs8111998 0.826 rs10421310 chr19:22768069 G/A cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs6840360 0.593 rs2089811 chr4:152685171 C/T cg22705602 chr4:152727874 NA 0.34 5.94 0.47 2.71e-8 Intelligence (multi-trait analysis); TGCT cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg00343986 chr7:65444356 GUSB -0.26 -6.12 -0.48 1.15e-8 Aortic root size; TGCT cis rs4242434 0.757 rs2280104 chr8:22525980 C/T cg03733263 chr8:22462867 KIAA1967 1.03 15.98 0.82 6.64e-32 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs8077889 0.672 rs1234612 chr17:41840802 A/G cg26893861 chr17:41843967 DUSP3 1.12 19.55 0.87 1.08e-39 Triglycerides; TGCT cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs3806843 1.000 rs7710794 chr5:140209467 T/G cg19875535 chr5:140030758 IK 0.35 5.86 0.47 3.93e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9303401 0.659 rs62083525 chr17:56658088 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs9788721 0.806 rs72738704 chr15:78719832 G/C cg18825076 chr15:78729989 IREB2 -0.34 -5.25 -0.43 6.28e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs67478160 0.619 rs11623546 chr14:104269098 A/G cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs11190604 1.000 rs2489053 chr10:102353341 A/G cg16342193 chr10:102329863 NA -0.41 -4.82 -0.4 4.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3820928 0.874 rs2177593 chr2:227833869 G/A cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs858239 0.704 rs466240 chr7:23338774 C/T cg05602783 chr7:23145260 KLHL7 0.57 4.66 0.39 8.07e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs6504950 0.720 rs2877634 chr17:52987545 A/G cg07707039 chr17:53042137 COX11 0.26 4.47 0.37 1.71e-5 Breast cancer; TGCT cis rs2120019 1.000 rs2415253 chr15:75375699 A/G cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs9611519 0.780 rs1535048 chr22:41684093 C/T cg06634786 chr22:41940651 POLR3H -0.64 -5.76 -0.46 6.22e-8 Neuroticism; TGCT cis rs7727544 0.684 rs274546 chr5:131699867 A/G cg24060327 chr5:131705240 SLC22A5 -0.61 -6.61 -0.51 1.04e-9 Blood metabolite levels; TGCT cis rs734999 0.588 rs10910098 chr1:2533250 C/A cg18854424 chr1:2615690 NA 0.44 5.1 0.42 1.22e-6 Ulcerative colitis; TGCT cis rs12950390 0.853 rs4793647 chr17:45854090 G/C cg24803719 chr17:45855879 NA -0.5 -5.05 -0.41 1.51e-6 IgG glycosylation; TGCT cis rs9910055 0.530 rs2269905 chr17:42294462 A/G cg13607699 chr17:42295918 UBTF 0.97 11.16 0.71 1.87e-20 Total body bone mineral density; TGCT cis rs10782582 0.593 rs11802717 chr1:76124648 C/T cg03433033 chr1:76189801 ACADM -0.63 -7.27 -0.55 3.6e-11 Daytime sleep phenotypes; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg06896619 chr17:61851486 DDX42;CCDC47 0.51 5.0 0.41 1.9e-6 Prudent dietary pattern; TGCT cis rs806215 1.000 rs712704 chr7:127258208 A/G cg25922125 chr7:127225783 GCC1 -0.62 -6.46 -0.5 2.14e-9 Type 2 diabetes; TGCT cis rs4555082 0.834 rs2735826 chr14:105710866 G/A cg01266790 chr14:105781312 PACS2 0.55 4.49 0.37 1.58e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs2721195 0.719 rs4925812 chr8:145808035 C/T cg17328964 chr8:145687451 CYHR1 -0.42 -5.51 -0.44 1.99e-7 Age at first birth; TGCT cis rs12220238 0.554 rs11001029 chr10:76154777 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.17 0.48 9.08e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs6582630 0.502 rs1115515 chr12:38279830 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.19e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs2224391 1.000 rs9784870 chr6:5261359 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -6.05 -0.48 1.61e-8 Height; TGCT cis rs7917772 0.582 rs10883744 chr10:104347247 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9894429 1.000 rs4074915 chr17:79579230 G/A cg21028142 chr17:79581711 NPLOC4 -0.29 -6.81 -0.52 3.83e-10 Eye color traits; TGCT cis rs4820792 0.725 rs7289973 chr22:29121760 G/C cg03733026 chr22:29445468 ZNRF3 0.25 4.89 0.4 3.01e-6 Breast size; TGCT cis rs1949733 0.656 rs2688243 chr4:8436286 A/G cg11789530 chr4:8429930 ACOX3 0.58 5.2 0.42 8.11e-7 Response to antineoplastic agents; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg08736216 chr1:53307985 ZYG11A 0.29 5.93 0.47 2.8e-8 Monocyte count; TGCT cis rs288326 0.561 rs17265894 chr2:183858168 A/G cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs6138458 0.626 rs6138473 chr20:25012155 A/G cg26195577 chr20:24973756 C20orf3 -0.89 -6.8 -0.52 3.86e-10 Blood protein levels; TGCT cis rs778371 0.748 rs2675953 chr2:233749565 G/C cg08000102 chr2:233561755 GIGYF2 -0.6 -6.42 -0.5 2.62e-9 Schizophrenia; TGCT cis rs7267979 1.000 rs2500405 chr20:25360826 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3796352 1.000 rs7622420 chr3:53111069 A/G cg07884673 chr3:53033167 SFMBT1 0.54 6.2 0.49 7.73e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs62380364 0.774 rs55740951 chr5:88153874 C/T cg22951263 chr5:87985283 NA -0.47 -4.49 -0.37 1.58e-5 Intelligence (multi-trait analysis); TGCT cis rs78707713 0.560 rs61848398 chr10:71226103 G/A cg14388049 chr10:71211838 TSPAN15 -0.39 -4.68 -0.39 7.52e-6 Venous thromboembolism; TGCT cis rs669446 0.828 rs656131 chr1:44129099 C/T cg12908607 chr1:44402522 ARTN 0.46 4.96 0.41 2.25e-6 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs886126 0.950 rs2078851 chr12:111690579 C/T cg10833066 chr12:111807467 FAM109A -0.33 -5.67 -0.45 9.38e-8 Coronary heart disease; TGCT cis rs9486719 1.000 rs2472897 chr6:96870569 G/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs2840044 1.000 rs9891800 chr17:33895015 G/C cg05299278 chr17:33885742 SLFN14 -0.23 -5.32 -0.43 4.65e-7 Response to radiotherapy in cancer (late toxicity); TGCT cis rs7647973 0.667 rs4241405 chr3:49642027 C/T cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs6964587 1.000 rs35653487 chr7:91745441 C/G cg17063962 chr7:91808500 NA 0.88 9.42 0.65 3.2e-16 Breast cancer; TGCT trans rs57221529 0.766 rs72704799 chr5:551457 C/G cg25482853 chr8:67687455 SGK3 1.2 9.5 0.65 2.01e-16 Lung disease severity in cystic fibrosis; TGCT cis rs2862064 1.000 rs6555787 chr5:156433699 T/C cg12943317 chr5:156479607 HAVCR1 -0.45 -5.77 -0.46 5.83e-8 Platelet count; TGCT cis rs79349575 0.783 rs4793991 chr17:47001801 A/G cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs12477438 0.520 rs13004491 chr2:99738008 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs62244186 0.715 rs11130032 chr3:44704083 G/A cg04389838 chr3:44770851 ZNF501 -0.39 -5.11 -0.42 1.18e-6 Depressive symptoms; TGCT cis rs290268 0.874 rs290988 chr9:93562955 C/G cg02608019 chr9:93564028 SYK 0.44 4.44 0.37 1.94e-5 Platelet count; TGCT cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs7172809 0.599 rs74026910 chr15:77728444 G/C cg22256960 chr15:77711686 NA -0.51 -4.87 -0.4 3.32e-6 Glucose homeostasis traits; TGCT cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg00814883 chr7:100076585 TSC22D4 -0.82 -8.37 -0.6 1.03e-13 Platelet count; TGCT cis rs3935685 0.874 rs11072663 chr15:77999542 A/G cg25212270 chr15:78015279 NA 0.26 5.55 0.45 1.66e-7 Intelligence (multi-trait analysis); TGCT cis rs9322193 0.923 rs10747275 chr6:149943918 C/T cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs709400 0.628 rs7154246 chr14:103876794 G/A cg26031613 chr14:104095156 KLC1 -0.83 -9.19 -0.64 1.17e-15 Body mass index; TGCT cis rs28595532 0.920 rs116612909 chr4:119749823 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs10875746 0.903 rs4760681 chr12:48505230 C/T cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs7224685 0.515 rs7207986 chr17:3979949 G/A cg09580393 chr17:4869866 SPAG7 -0.39 -4.5 -0.37 1.56e-5 Type 2 diabetes; TGCT trans rs2624839 0.704 rs1046956 chr3:50222926 T/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.78 -7.03 -0.53 1.24e-10 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg24531977 chr5:56204891 C5orf35 -0.87 -7.03 -0.53 1.22e-10 Initial pursuit acceleration; TGCT cis rs9400467 0.537 rs12215291 chr6:111463520 A/G cg15721981 chr6:111408429 SLC16A10 0.68 4.48 0.37 1.69e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs1218582 0.651 rs4845396 chr1:154828409 A/G cg09359103 chr1:154839909 KCNN3 0.5 7.51 0.56 1.01e-11 Prostate cancer; TGCT cis rs79976124 0.837 rs11751994 chr6:66644028 A/C cg07460842 chr6:66804631 NA 0.57 5.22 0.42 7.44e-7 Type 2 diabetes; TGCT cis rs7833790 0.654 rs6415652 chr8:82702257 G/A cg27398817 chr8:82754497 SNX16 -0.62 -4.76 -0.39 5.33e-6 Diastolic blood pressure; TGCT cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg05025164 chr4:1340916 KIAA1530 -0.83 -7.15 -0.54 6.74e-11 Longevity; TGCT cis rs57590327 0.503 rs6764261 chr3:81620370 T/G cg07356753 chr3:81810745 GBE1 -0.62 -5.24 -0.43 6.69e-7 Extraversion; TGCT cis rs6490294 0.748 rs73422316 chr12:112273674 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs447921 0.861 rs117544870 chr17:74415206 T/G cg09812376 chr17:74270190 QRICH2 -0.46 -4.6 -0.38 1.01e-5 Mitochondrial DNA levels; TGCT cis rs2594989 0.895 rs2606739 chr3:11394611 C/A cg00170343 chr3:11313890 ATG7 0.68 5.13 0.42 1.1e-6 Circulating chemerin levels; TGCT cis rs854765 0.551 rs6502626 chr17:17849450 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.71 0.57 3.44e-12 Total body bone mineral density; TGCT trans rs797680 0.856 rs682514 chr1:93719430 A/C cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs2721195 0.845 rs4244611 chr8:145739924 G/A cg15320075 chr8:145703422 NA 0.7 7.04 0.53 1.17e-10 Age at first birth; TGCT cis rs1534166 0.601 rs13324779 chr3:133510413 G/A cg08048268 chr3:133502702 NA 0.45 5.58 0.45 1.44e-7 Alcohol consumption (transferrin glycosylation); TGCT cis rs9916302 0.706 rs6503504 chr17:37514412 A/G cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs2760061 0.655 rs686533 chr1:228119604 A/G cg02753203 chr1:228287806 NA -0.35 -6.84 -0.52 3.29e-10 Diastolic blood pressure; TGCT cis rs57994353 0.897 rs36101132 chr9:139367566 G/A cg13741927 chr9:139327495 INPP5E -0.25 -5.59 -0.45 1.38e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs854572 0.600 rs705382 chr7:94955221 C/G cg19678392 chr7:94953810 PON1 -0.59 -6.69 -0.52 6.79e-10 Paraoxonase activity; TGCT cis rs838147 0.537 rs485186 chr19:49207206 A/G cg13540341 chr19:49222985 MAMSTR -0.37 -4.91 -0.4 2.84e-6 Dietary macronutrient intake; TGCT cis rs3806843 0.576 rs246041 chr5:140331128 C/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs17767294 0.541 rs72845051 chr6:27610545 G/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Parkinson's disease; TGCT cis rs1476679 0.962 rs34995835 chr7:99990364 T/G cg13334819 chr7:99746414 C7orf59 0.63 5.31 0.43 4.86e-7 Alzheimer's disease (late onset); TGCT cis rs7666738 0.830 rs11726604 chr4:99000969 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7586879 1.000 rs1865687 chr2:25112885 G/A cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg27286337 chr10:134555280 INPP5A 0.41 4.89 0.4 3.1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1218582 0.772 rs10908445 chr1:154849590 A/G cg09359103 chr1:154839909 KCNN3 0.63 12.67 0.75 4.02e-24 Prostate cancer; TGCT cis rs8180040 0.903 rs11710013 chr3:47296921 T/C cg27129171 chr3:47204927 SETD2 0.69 8.59 0.61 3.04e-14 Colorectal cancer; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg01802117 chr1:53393560 SCP2 0.39 4.6 0.38 1.05e-5 Monocyte count; TGCT cis rs10883723 0.810 rs1056857 chr10:104240003 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs904251 0.861 rs1776456 chr6:37484698 C/G cg08126542 chr6:37504118 NA -0.43 -5.92 -0.47 2.99e-8 Cognitive performance; TGCT cis rs35306767 0.903 rs11253460 chr10:887382 C/G cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs6815814 0.950 rs5743557 chr4:38806827 G/A cg02016764 chr4:38805732 TLR1 -0.35 -5.58 -0.45 1.44e-7 Breast cancer; TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg19536664 chr17:6899085 ALOX12 0.38 6.28 0.49 5.32e-9 Tonsillectomy; TGCT cis rs7772486 0.875 rs2474356 chr6:146296798 G/A cg05347473 chr6:146136440 FBXO30 0.56 5.33 0.43 4.4e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs2727020 0.566 rs10839234 chr11:49185524 C/T cg03929089 chr4:120376271 NA -0.69 -7.92 -0.58 1.17e-12 Coronary artery disease; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg26757820 chr10:76349278 ADK 0.95 7.01 0.53 1.39e-10 Gambling; TGCT cis rs6071524 0.508 rs2425367 chr20:37385240 C/T cg09937324 chr20:37376998 ACTR5 0.54 4.45 0.37 1.91e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs737008 0.960 rs949429 chr16:11376029 C/T cg00044050 chr16:11439710 C16orf75 -0.71 -7.23 -0.54 4.44e-11 Obesity-related traits; TGCT cis rs7178572 0.568 rs1602925 chr15:77685857 T/C cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs4891159 0.824 rs17059362 chr18:74144307 G/A cg24786174 chr18:74118243 ZNF516 -0.53 -6.98 -0.53 1.6e-10 Longevity; TGCT cis rs769267 0.930 rs3794990 chr19:19610030 A/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs801193 0.844 rs7779971 chr7:66161790 T/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs4455778 0.600 rs34886560 chr7:49120470 G/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs2191566 0.747 rs4803667 chr19:44533604 T/C cg03039196 chr19:44506973 ZNF230 0.56 4.76 0.39 5.38e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs10751667 0.666 rs6597967 chr11:950583 G/T cg06064525 chr11:970664 AP2A2 -0.35 -8.06 -0.59 5.6e-13 Alzheimer's disease (late onset); TGCT cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg16497277 chr3:49208875 KLHDC8B -0.54 -5.18 -0.42 8.8e-7 Menarche (age at onset); TGCT cis rs3099143 1.000 rs3106375 chr15:77142243 T/C cg21673338 chr15:77095150 SCAPER -0.51 -4.88 -0.4 3.17e-6 Recalcitrant atopic dermatitis; TGCT cis rs6969780 0.915 rs4722657 chr7:27157756 G/A cg04317399 chr7:27170313 HOXA4 -0.44 -4.87 -0.4 3.3e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs12762955 0.561 rs6560863 chr10:1013535 C/A cg20503657 chr10:835505 NA -0.39 -5.04 -0.41 1.58e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs2070729 0.523 rs743562 chr5:131872383 C/T cg02551604 chr5:131831745 NA 0.47 4.53 0.38 1.39e-5 Platelet count; TGCT cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg03517284 chr6:25882590 NA -0.69 -7.5 -0.56 1.07e-11 Blood metabolite levels; TGCT cis rs13256369 0.901 rs12679831 chr8:8566411 T/G cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs13064411 0.696 rs2399479 chr3:113227050 G/A cg18753928 chr3:113234510 CCDC52 -0.7 -5.61 -0.45 1.23e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs597539 0.652 rs627731 chr11:68698663 A/C cg04772025 chr11:68637568 NA 0.6 6.75 0.52 5.08e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7010267 0.716 rs3134065 chr8:119959921 T/C cg17171407 chr8:119960777 TNFRSF11B 0.28 5.1 0.42 1.25e-6 Total body bone mineral density (age 45-60); TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg07167872 chr1:205819463 PM20D1 0.55 6.99 0.53 1.47e-10 Menarche (age at onset); TGCT cis rs6141769 0.542 rs6058845 chr20:31323919 G/T cg13636640 chr20:31349939 DNMT3B 0.52 4.55 0.38 1.26e-5 Subjective well-being; TGCT cis rs10484885 0.824 rs112817281 chr6:90555658 G/A cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs477895 0.878 rs7478730 chr11:64018827 C/T cg04317338 chr11:64019027 PLCB3 0.81 6.9 0.53 2.35e-10 Mean platelet volume; TGCT cis rs3096299 0.967 rs2965827 chr16:89457350 A/C cg06640241 chr16:89574553 SPG7 -0.69 -6.62 -0.51 9.72e-10 Multiple myeloma (IgH translocation); TGCT cis rs9457247 1.000 rs422694 chr6:167406074 G/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT trans rs9859260 0.710 rs34906439 chr3:195779706 A/G cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs9486719 1.000 rs9400016 chr6:96940883 G/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs1997103 0.954 rs2030807 chr7:55378485 A/G cg17469321 chr7:55412551 NA 0.66 6.94 0.53 1.92e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7267979 0.932 rs424487 chr20:25468131 C/G cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13191362 1.000 rs66534429 chr6:163003322 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg20607798 chr8:58055168 NA 0.62 5.17 0.42 9.2e-7 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs80153759 chr7:106944145 C/A cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs9814567 1.000 rs4974483 chr3:134219001 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -9.27 -0.64 7.51e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs529866 0.519 rs4451969 chr16:11383519 A/G cg00044050 chr16:11439710 C16orf75 -0.65 -6.77 -0.52 4.53e-10 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9926296 0.565 rs8055825 chr16:89832848 C/T cg26513180 chr16:89883248 FANCA 1.04 14.77 0.8 4.11e-29 Vitiligo; TGCT trans rs1814175 0.817 rs6486046 chr11:49997017 T/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs7666738 1.000 rs13144055 chr4:99026849 A/G cg17366294 chr4:99064904 C4orf37 0.76 7.12 0.54 7.6e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs17001868 0.527 rs9611324 chr22:40781162 T/C cg07138101 chr22:40742427 ADSL 0.71 5.38 0.44 3.55e-7 Mammographic density (dense area); TGCT cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg03264133 chr6:25882463 NA 0.49 5.23 0.43 7e-7 Blood metabolite levels; TGCT cis rs7172809 0.548 rs79036117 chr15:77474832 G/A cg22256960 chr15:77711686 NA -0.49 -4.63 -0.38 9.01e-6 Glucose homeostasis traits; TGCT cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.76 -7.09 -0.54 8.94e-11 Intelligence (multi-trait analysis); TGCT cis rs2832191 0.716 rs8132085 chr21:30501389 G/T cg08807101 chr21:30365312 RNF160 -0.61 -5.79 -0.46 5.31e-8 Dental caries; TGCT cis rs9814567 1.000 rs7374158 chr3:134270156 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1348850 0.793 rs13027299 chr2:178455501 T/G cg22681709 chr2:178499509 PDE11A -0.45 -5.28 -0.43 5.7e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs6969780 0.841 rs2301720 chr7:27196069 A/C cg04321618 chr7:27170880 HOXA4 -0.51 -4.46 -0.37 1.83e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6912958 0.559 rs2985039 chr6:88041757 A/G cg10393598 chr6:87862264 NA -0.31 -4.51 -0.38 1.5e-5 Monocyte percentage of white cells; TGCT cis rs889312 0.500 rs3099460 chr5:56133748 G/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs2204008 0.774 rs4534658 chr12:38246783 G/A cg13010199 chr12:38710504 ALG10B 0.61 4.7 0.39 6.69e-6 Bladder cancer; TGCT cis rs79387448 0.808 rs77518775 chr2:103237642 T/C cg09003973 chr2:102972529 NA 0.87 5.24 0.43 6.8e-7 Gut microbiota (bacterial taxa); TGCT cis rs1205863 0.915 rs1205880 chr6:11947263 T/C cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs62229266 0.740 rs2835233 chr21:37393582 A/G cg08632701 chr21:37451849 NA -0.14 -4.44 -0.37 1.99e-5 Mitral valve prolapse; TGCT cis rs9303401 0.573 rs35104446 chr17:57180234 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg06108461 chr20:60628389 TAF4 -0.75 -11.02 -0.7 4.27e-20 Body mass index; TGCT cis rs115056730 0.520 rs114113305 chr2:98189209 A/T cg26665480 chr2:98280029 ACTR1B -0.96 -4.48 -0.37 1.67e-5 Monocyte chemoattractant protein-3 levels; TGCT cis rs2458413 0.543 rs2514658 chr8:105337871 G/A cg13045555 chr8:105342365 NA -0.39 -6.6 -0.51 1.05e-9 Paget's disease; TGCT cis rs4906332 1.000 rs17617094 chr14:103893428 T/C cg26031613 chr14:104095156 KLC1 -0.54 -4.82 -0.4 4.04e-6 Coronary artery disease; TGCT cis rs34172651 0.517 rs11642954 chr16:24824248 G/A cg06028605 chr16:24865363 SLC5A11 0.41 4.6 0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT cis rs57244997 0.929 rs9346891 chr6:162369311 G/A cg17173639 chr6:162384350 PARK2 -0.41 -4.53 -0.38 1.38e-5 Mosquito bite size; TGCT cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg21862992 chr11:68658383 NA 0.46 6.4 0.5 2.89e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6938 0.534 rs11854704 chr15:75221015 C/T cg10253484 chr15:75165896 SCAMP2 -0.54 -4.83 -0.4 3.99e-6 Breast cancer; TGCT cis rs60432013 0.584 rs3764167 chr14:23519975 A/G cg15959986 chr14:23564790 ACIN1;C14orf119 -0.88 -4.47 -0.37 1.75e-5 Red cell distribution width; TGCT cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs3008870 0.958 rs34367328 chr1:67445321 T/C cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs41271951 0.512 rs76649628 chr1:151041851 A/G cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs79349575 0.783 rs12603969 chr17:47034419 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.48 -0.37 1.67e-5 Type 2 diabetes; TGCT cis rs1857353 1.000 rs4949855 chr1:75917162 G/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7662987 0.517 rs1453873 chr4:100022571 T/C cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs10927875 1.000 rs10927875 chr1:16299312 A/G cg21385522 chr1:16154831 NA 0.77 8.62 0.61 2.67e-14 Dilated cardiomyopathy; TGCT cis rs514406 0.621 rs881198 chr1:53196440 C/T cg08859206 chr1:53392774 SCP2 0.35 4.9 0.4 2.98e-6 Monocyte count; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg10263370 chr3:44754102 ZNF502 -0.42 -5.02 -0.41 1.78e-6 Depressive symptoms; TGCT cis rs7617773 0.817 rs13059037 chr3:48287879 A/G cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.64e-10 Coronary artery disease; TGCT cis rs80282103 0.618 rs57514701 chr10:1146169 G/A cg08668510 chr10:1095578 IDI1 1.05 5.31 0.43 4.8e-7 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg08280861 chr8:58055591 NA 0.36 4.91 0.4 2.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.542 rs6912740 chr6:8439959 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs1008375 0.864 rs4698196 chr4:17574735 T/C cg10189774 chr4:17578691 LAP3 0.6 4.97 0.41 2.17e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9640161 0.659 rs17837498 chr7:150009679 A/G cg17279839 chr7:150038598 RARRES2 0.42 4.45 0.37 1.88e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2762353 0.574 rs4409177 chr6:25694491 T/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.75 7.75 0.57 2.9e-12 Blood metabolite levels; TGCT cis rs1008375 1.000 rs2215450 chr4:17675394 T/G cg18681998 chr4:17616180 MED28 0.93 10.58 0.69 4.83e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs951366 0.873 rs823118 chr1:205723572 C/T cg24503407 chr1:205819492 PM20D1 0.42 5.16 0.42 9.41e-7 Menarche (age at onset); TGCT cis rs6089584 0.566 rs6061401 chr20:60607482 G/A cg06108461 chr20:60628389 TAF4 -0.45 -5.65 -0.45 1.04e-7 Body mass index; TGCT cis rs7804356 0.651 rs56374720 chr7:26815776 G/A cg03456212 chr7:26904342 SKAP2 -0.54 -4.6 -0.38 1.04e-5 Type 1 diabetes; TGCT cis rs909674 0.731 rs6001594 chr22:39837472 C/T cg02038168 chr22:39784481 NA -0.72 -5.42 -0.44 3.03e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1008375 0.932 rs11934968 chr4:17667766 A/G cg10189774 chr4:17578691 LAP3 0.52 4.44 0.37 1.96e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.765 rs1974435 chr17:61994096 G/A cg06873352 chr17:61820015 STRADA -0.48 -5.56 -0.45 1.59e-7 Prudent dietary pattern; TGCT cis rs13188771 0.525 rs10477735 chr5:100918100 T/C cg17598923 chr5:101119084 NA 0.48 4.48 0.37 1.67e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs11971779 0.838 rs11764161 chr7:139115198 T/C cg07862535 chr7:139043722 LUC7L2 0.75 5.43 0.44 2.86e-7 Diisocyanate-induced asthma; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg20007245 chr22:24372913 LOC391322 -0.7 -6.93 -0.53 2.09e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1580019 0.713 rs2122632 chr7:32524686 A/G cg06627557 chr7:32535165 LSM5;AVL9 -1.0 -10.41 -0.68 1.27e-18 Cognitive ability; TGCT cis rs1008375 1.000 rs10440301 chr4:17663199 G/A cg18681998 chr4:17616180 MED28 0.95 10.44 0.68 1.1e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4478037 0.822 rs9825335 chr3:33123292 A/C cg19404215 chr3:33155277 CRTAP 0.98 5.13 0.42 1.1e-6 Major depressive disorder; TGCT cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg27211696 chr2:191398769 TMEM194B 0.29 5.3 0.43 5.19e-7 Pulse pressure; TGCT cis rs6831352 0.879 rs2851255 chr4:100042103 C/G cg12011299 chr4:100065546 ADH4 0.42 4.92 0.4 2.74e-6 Alcohol dependence; TGCT cis rs35146811 0.735 rs1727130 chr7:99811464 C/G cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs644799 0.544 rs555556 chr11:95618425 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.57 5.85 0.47 4.03e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7772486 0.754 rs4895682 chr6:146062861 G/A cg13319975 chr6:146136371 FBXO30 0.56 4.95 0.41 2.37e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg04267008 chr7:1944627 MAD1L1 0.38 5.15 0.42 1e-6 Bipolar disorder and schizophrenia; TGCT cis rs752092 1.000 rs11247277 chr15:101784664 A/G cg19997662 chr15:101784653 CHSY1 -0.31 -5.89 -0.47 3.44e-8 Corneal structure; TGCT cis rs931127 0.547 rs3886859 chr11:65458310 C/T cg17480646 chr11:65405466 SIPA1 -0.43 -5.74 -0.46 6.76e-8 Systemic lupus erythematosus; TGCT cis rs9311474 0.967 rs610060 chr3:52273421 G/A cg07507251 chr3:52567010 NT5DC2 -0.42 -5.81 -0.46 4.94e-8 Electroencephalogram traits; TGCT cis rs9660992 0.573 rs1318187 chr1:205206172 T/A cg00857998 chr1:205179979 DSTYK 0.51 4.67 0.39 7.77e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs9926296 0.687 rs258317 chr16:89732238 C/T cg04287289 chr16:89883240 FANCA -0.54 -4.99 -0.41 2.01e-6 Vitiligo; TGCT cis rs8020441 1.000 rs67186984 chr14:51169287 C/T cg04730355 chr14:51134070 SAV1 0.73 6.02 0.48 1.84e-8 Cognitive performance; TGCT cis rs1372520 0.684 rs1837891 chr4:90736131 C/G cg14346243 chr4:90757452 SNCA 0.65 5.52 0.44 1.88e-7 Neuroticism; TGCT cis rs9325144 0.505 rs826893 chr12:39100536 A/G cg13010199 chr12:38710504 ALG10B -0.56 -4.6 -0.38 1.04e-5 Morning vs. evening chronotype; TGCT cis rs28595532 0.920 rs55806110 chr4:119742583 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs1577917 0.771 rs9353318 chr6:86231721 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.6 5.27 0.43 5.84e-7 Response to antipsychotic treatment; TGCT cis rs10751667 0.666 rs7936830 chr11:959686 A/G cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT cis rs7715806 0.500 rs17563995 chr5:75007556 A/G cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs13202913 0.581 rs12662412 chr6:151824309 T/A cg03627880 chr6:151815985 C6orf97 -0.62 -5.56 -0.45 1.6e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs910316 0.737 rs424120 chr14:75482828 G/T cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.38e-7 Height; TGCT cis rs11971779 0.680 rs6947215 chr7:139026638 A/G cg07862535 chr7:139043722 LUC7L2 0.58 4.69 0.39 6.97e-6 Diisocyanate-induced asthma; TGCT cis rs732765 0.734 rs10438025 chr14:75183239 G/A cg06637938 chr14:75390232 RPS6KL1 -0.55 -4.48 -0.37 1.71e-5 Non-small cell lung cancer; TGCT cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg18876405 chr7:65276391 NA 0.36 5.7 0.46 8.31e-8 Aortic root size; TGCT cis rs4660261 0.526 rs810680 chr1:44347856 C/T cg12908607 chr1:44402522 ARTN -0.66 -8.26 -0.6 1.85e-13 Intelligence (multi-trait analysis); TGCT cis rs67072384 0.901 rs11235580 chr11:72455645 G/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs6684514 0.961 rs12029695 chr1:156299847 C/T cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2236918 0.710 rs3094880 chr1:242020391 T/A cg04158730 chr1:242011433 EXO1 0.56 5.14 0.42 1.05e-6 Menopause (age at onset); TGCT cis rs8072100 0.967 rs4239162 chr17:45755810 G/A cg08085267 chr17:45401833 C17orf57 -0.42 -4.6 -0.38 1.04e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg22168489 chr12:122356033 WDR66 0.2 4.73 0.39 6.08e-6 Mean corpuscular volume; TGCT cis rs1205863 1.000 rs1205882 chr6:11947708 C/T cg07106625 chr6:11870215 NA -0.55 -5.77 -0.46 5.95e-8 Disc degeneration (lumbar); TGCT cis rs587847 0.540 rs62637 chr15:37681202 C/T cg16890051 chr15:37175029 LOC145845 -0.37 -4.44 -0.37 1.95e-5 Intraocular pressure; TGCT cis rs6089829 0.890 rs6062775 chr20:61663650 T/C cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg15691649 chr6:25882328 NA -0.36 -4.71 -0.39 6.5e-6 Blood metabolite levels; TGCT cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -4.72 -0.39 6.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.542 rs915353 chr6:8440370 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.56 0.45 1.55e-7 Motion sickness; TGCT trans rs11088226 0.681 rs9622 chr21:33951068 T/C cg09050820 chr6:167586206 TCP10L2 0.76 7.31 0.55 2.88e-11 Gastritis; TGCT cis rs28595532 0.920 rs115076001 chr4:119764346 T/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs911555 0.755 rs7147664 chr14:103963420 G/A cg12935359 chr14:103987150 CKB -0.33 -4.59 -0.38 1.07e-5 Intelligence (multi-trait analysis); TGCT cis rs77741769 0.571 rs3861797 chr12:121255334 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs11577318 0.685 rs4262530 chr1:26682034 G/A cg14210634 chr1:25870291 LDLRAP1 0.49 4.46 0.37 1.84e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs17473412 0.963 rs56006955 chr5:122718341 C/T cg15125798 chr5:122621645 NA -0.57 -5.13 -0.42 1.08e-6 Total body bone mineral density; TGCT cis rs7100689 0.622 rs7090351 chr10:82142047 T/G cg01528321 chr10:82214614 TSPAN14 0.79 8.14 0.59 3.57e-13 Post bronchodilator FEV1; TGCT cis rs11098499 0.722 rs28713555 chr4:120251995 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs6088580 0.660 rs6059893 chr20:33105897 T/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs6545883 0.929 rs778154 chr2:61646631 T/C cg15711740 chr2:61764176 XPO1 0.59 5.4 0.44 3.28e-7 Tuberculosis; TGCT cis rs7043114 0.525 rs1053446 chr9:95146761 T/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.59 -0.45 1.36e-7 Height; TGCT cis rs4851266 1.000 rs4851266 chr2:100818479 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.25 -0.43 6.39e-7 Educational attainment; TGCT cis rs2469997 1.000 rs2470009 chr8:120359377 T/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs10851411 0.862 rs4923948 chr15:42826823 C/A cg23803468 chr15:43513504 EPB42 0.29 5.38 0.43 3.6e-7 Glucose homeostasis traits; TGCT trans rs12339966 0.615 rs62529425 chr9:11358789 A/G cg03488587 chr11:64876988 C11orf2 0.3 6.92 0.53 2.12e-10 Systolic blood pressure; TGCT cis rs10276381 0.901 rs73300638 chr7:28187344 A/C cg23620719 chr7:28220237 JAZF1 0.99 5.13 0.42 1.08e-6 Crohn's disease; TGCT cis rs4409675 0.576 rs7533918 chr1:28230667 G/A cg23691781 chr1:28212827 C1orf38 0.26 5.44 0.44 2.76e-7 Corneal astigmatism; TGCT cis rs7267979 1.000 rs2482928 chr20:25331530 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9914988 0.619 rs34580233 chr17:27317935 A/T cg17523868 chr17:27313033 SEZ6 -0.58 -4.9 -0.4 2.99e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs950169 0.881 rs34117475 chr15:85108443 T/C cg11189052 chr15:85197271 WDR73 0.77 6.42 0.5 2.68e-9 Schizophrenia; TGCT cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg18402987 chr7:1209562 NA 0.75 6.35 0.5 3.67e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs909002 0.849 rs10798881 chr1:32101775 G/C cg11573219 chr1:32083031 HCRTR1 -0.46 -6.05 -0.48 1.58e-8 Intelligence (multi-trait analysis); TGCT cis rs7937682 0.961 rs11828343 chr11:111491322 A/G cg09085632 chr11:111637200 PPP2R1B 0.96 9.07 0.63 2.23e-15 Primary sclerosing cholangitis; TGCT cis rs7208859 0.623 rs9911490 chr17:29073013 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7769051 1.000 rs58832890 chr6:133127139 C/T cg07930552 chr6:133119739 C6orf192 0.95 5.13 0.42 1.1e-6 Type 2 diabetes nephropathy; TGCT cis rs66782572 1 rs66782572 chr3:52567617 A/G cg07507251 chr3:52567010 NT5DC2 0.51 7.63 0.57 5.48e-12 Hemoglobin concentration; TGCT cis rs933688 0.938 rs10063683 chr5:90714595 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.06 0.59 5.53e-13 Smoking behavior; TGCT cis rs3617 0.625 rs6769789 chr3:52874446 C/T cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9303401 0.659 rs35564417 chr17:56718286 G/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs9611565 0.512 rs715498 chr22:42148467 G/A cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs7119 0.679 rs12902698 chr15:77809010 A/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs9300255 0.602 rs1716160 chr12:123700225 C/T cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs17712049 0.908 rs9639997 chr7:48201016 G/A cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs709400 0.894 rs10143293 chr14:104063014 G/A cg26031613 chr14:104095156 KLC1 1.14 15.24 0.81 3.31e-30 Body mass index; TGCT cis rs4730250 0.707 rs257375 chr7:106799043 A/G cg02696742 chr7:106810147 HBP1 -0.65 -5.3 -0.43 5.23e-7 Osteoarthritis; TGCT cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.43 -4.85 -0.4 3.65e-6 Blood metabolite levels; TGCT cis rs910316 0.737 rs175424 chr14:75626257 T/C cg11812906 chr14:75593930 NEK9 -0.64 -5.91 -0.47 3.14e-8 Height; TGCT cis rs4888262 0.526 rs7205992 chr16:74590578 T/A cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 7.94e-11 Testicular germ cell tumor; TGCT cis rs2549003 1.000 rs10214312 chr5:131821866 T/G cg00255919 chr5:131827918 IRF1 0.2 4.65 0.39 8.22e-6 Asthma (sex interaction); TGCT cis rs5769765 0.865 rs4824108 chr22:50271428 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg21724239 chr8:58056113 NA 0.41 4.87 0.4 3.33e-6 Developmental language disorder (linguistic errors); TGCT cis rs17433780 0.808 rs7541867 chr1:89513537 G/A cg09516651 chr1:89888402 LOC400759 0.26 4.94 0.41 2.48e-6 Carotid intima media thickness; TGCT cis rs909674 0.514 rs7423 chr22:39781429 C/T cg24399712 chr22:39784796 NA -1.04 -13.31 -0.77 1.21e-25 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7246657 0.943 rs13343471 chr19:37932130 A/G cg18154014 chr19:37997991 ZNF793 0.94 6.29 0.49 4.95e-9 Coronary artery calcification; TGCT cis rs597539 0.654 rs655816 chr11:68626405 A/G cg04772025 chr11:68637568 NA 0.61 6.7 0.52 6.38e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3784262 0.631 rs4646584 chr15:58305402 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.83e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs9951602 0.512 rs7234283 chr18:76640552 T/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs7917772 0.503 rs56219824 chr10:104302337 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9581857 0.547 rs7336332 chr13:28058404 A/G cg22138327 chr13:27999177 GTF3A 0.75 4.96 0.41 2.24e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7809950 1.000 rs7778270 chr7:107224667 A/G cg23024343 chr7:107201750 COG5 0.33 5.23 0.42 7.11e-7 Coronary artery disease; TGCT cis rs1420338 0.837 rs17753041 chr7:34176925 G/A cg01275685 chr7:34179230 BMPER -0.28 -5.0 -0.41 1.88e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs4925386 0.840 rs6143035 chr20:60920700 C/T cg24112000 chr20:60950667 NA 0.37 4.44 0.37 1.97e-5 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs60154123 0.505 rs76101197 chr1:210044089 T/C cg04352962 chr1:209979756 IRF6 0.69 4.73 0.39 6.04e-6 Coronary artery disease; TGCT cis rs7412746 0.658 rs4970987 chr1:150949682 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.55 0.38 1.25e-5 Melanoma; TGCT cis rs17221829 0.703 rs10765229 chr11:89392575 T/G cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs11190604 1.000 rs11190541 chr10:102203071 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6426558 0.537 rs648877 chr1:227283614 A/G cg10327440 chr1:227177885 CDC42BPA 0.61 7.42 0.55 1.59e-11 Neutrophil percentage of white cells; TGCT cis rs5750830 0.649 rs4337572 chr22:39800704 C/G cg05872129 chr22:39784769 NA -0.97 -8.79 -0.62 1.03e-14 Intelligence (multi-trait analysis); TGCT cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg11279151 chr3:101281821 RG9MTD1 -0.44 -9.51 -0.65 1.94e-16 Colonoscopy-negative controls vs population controls; TGCT trans rs4650994 0.816 rs2811301 chr1:178594196 T/C cg05059571 chr16:84539110 KIAA1609 0.41 7.51 0.56 1e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs751728 1.000 rs4711351 chr6:33754592 G/A cg13859433 chr6:33739653 LEMD2 -0.39 -7.23 -0.54 4.25e-11 Crohn's disease; TGCT cis rs2067615 0.579 rs4385986 chr12:107133775 C/T cg15890332 chr12:107067104 RFX4 0.3 5.93 0.47 2.85e-8 Heart rate; TGCT cis rs611744 0.967 rs859788 chr8:109227570 A/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs10782582 0.609 rs112205173 chr1:76310100 C/T cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs9611565 0.570 rs12159188 chr22:42121125 A/T cg13695892 chr22:41940480 POLR3H 0.87 8.74 0.62 1.33e-14 Vitiligo; TGCT cis rs6076065 0.748 rs2424542 chr20:23386800 C/T cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs9916302 0.904 rs4795355 chr17:37427382 C/T cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs7826238 0.601 rs2979206 chr8:8345581 G/C cg15556689 chr8:8085844 FLJ10661 0.6 5.55 0.45 1.62e-7 Systolic blood pressure; TGCT cis rs7267979 1.000 rs6037099 chr20:25356876 T/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 9.88 0.66 2.44e-17 Colorectal cancer; TGCT cis rs6725041 0.766 rs13415721 chr2:213092242 C/T cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs10883723 0.810 rs10883728 chr10:104269301 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.83 -9.13 -0.63 1.62e-15 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7312933 0.702 rs10785333 chr12:42586470 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.55 -5.06 -0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1023500 0.573 rs8135801 chr22:42475568 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Schizophrenia; TGCT cis rs9640161 0.789 rs6964110 chr7:150041836 A/C cg17279839 chr7:150038598 RARRES2 0.42 4.53 0.38 1.38e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs9926296 0.744 rs6860 chr16:89711120 C/T cg03388025 chr16:89894329 SPIRE2 -0.35 -5.05 -0.41 1.54e-6 Vitiligo; TGCT cis rs7267979 1.000 rs6050566 chr20:25351071 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7582180 0.700 rs4851303 chr2:100962064 T/C cg14675211 chr2:100938903 LONRF2 0.47 4.57 0.38 1.16e-5 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg17554472 chr22:41940697 POLR3H 0.48 4.92 0.4 2.64e-6 Vitiligo; TGCT cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg06634786 chr22:41940651 POLR3H 0.86 8.01 0.58 7.16e-13 Vitiligo; TGCT cis rs4478858 0.684 rs12121165 chr1:31725542 G/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.03 -0.41 1.67e-6 Alcohol dependence; TGCT cis rs933688 1.000 rs889213 chr5:90682151 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.05 0.59 5.84e-13 Smoking behavior; TGCT cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg12667521 chr19:29218732 NA 0.54 5.72 0.46 7.65e-8 Methadone dose in opioid dependence; TGCT cis rs2354432 0.607 rs11239980 chr1:146782698 G/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs6665290 0.669 rs7552783 chr1:227174145 T/C cg10327440 chr1:227177885 CDC42BPA -0.85 -13.09 -0.76 4.03e-25 Myeloid white cell count; TGCT cis rs2832191 1.000 rs2832189 chr21:30487414 C/T cg24692254 chr21:30365293 RNF160 -0.83 -8.71 -0.62 1.58e-14 Dental caries; TGCT cis rs3806843 0.547 rs246010 chr5:140336635 A/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs4285028 0.948 rs76593525 chr3:121690477 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs3020736 0.519 rs5996116 chr22:42517492 G/A cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4975709 0.569 rs2077269 chr5:1863506 C/T cg07747251 chr5:1868357 NA 0.39 5.58 0.45 1.47e-7 Cardiovascular disease risk factors; TGCT cis rs10791323 0.519 rs329663 chr11:133754543 A/G cg15485101 chr11:133734466 NA 0.38 5.49 0.44 2.13e-7 Childhood ear infection; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg26516362 chr5:178986906 RUFY1 -0.42 -4.6 -0.38 1.01e-5 Lung cancer; TGCT cis rs4711350 0.954 rs1536501 chr6:33727885 C/T cg18005901 chr6:33739558 LEMD2 0.57 5.92 0.47 2.9e-8 Schizophrenia; TGCT cis rs854765 0.547 rs9896837 chr17:17924868 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.01 0.58 7.06e-13 Total body bone mineral density; TGCT cis rs7666738 0.830 rs13134819 chr4:98919885 G/C cg05340658 chr4:99064831 C4orf37 0.53 6.11 0.48 1.21e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.590 rs2384361 chr2:26452209 T/C cg22920501 chr2:26401640 FAM59B -0.82 -6.45 -0.5 2.27e-9 Gut microbiome composition (summer); TGCT cis rs2820315 0.964 rs2644109 chr1:201797535 C/T cg12730843 chr1:201915899 LMOD1 -0.27 -4.77 -0.39 5.13e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs9859260 0.744 rs557527 chr3:195780709 G/A cg22891161 chr3:195456627 MUC20 0.23 4.65 0.39 8.28e-6 Mean corpuscular volume; TGCT cis rs2153535 0.580 rs2327061 chr6:8447231 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs13064447 0.817 rs11128611 chr3:12772365 C/G cg20675869 chr3:12750130 NA -0.2 -5.01 -0.41 1.79e-6 Major depression and alcohol dependence; TGCT cis rs7267979 1.000 rs4813563 chr20:25365340 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8067545 0.750 rs4005937 chr17:19959828 A/C cg13482628 chr17:19912719 NA 0.54 4.62 0.38 9.49e-6 Schizophrenia; TGCT cis rs2204008 0.522 rs117743143 chr12:38030824 C/T cg26384229 chr12:38710491 ALG10B 0.7 6.14 0.48 1.01e-8 Bladder cancer; TGCT cis rs911555 0.713 rs1107070 chr14:103970508 G/T cg23461800 chr14:103021989 NA -0.35 -4.55 -0.38 1.28e-5 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs6851253 chr4:99029980 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs72781680 0.898 rs10490751 chr2:24001356 A/G cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs9926296 0.681 rs12923946 chr16:89821080 C/T cg26513180 chr16:89883248 FANCA 0.74 7.25 0.55 3.86e-11 Vitiligo; TGCT cis rs67311347 1.000 rs34762643 chr3:40475433 C/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs7772486 0.686 rs1292334 chr6:145968288 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.91 0.66 2.12e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 0.931 rs9912203 chr17:41445145 A/G cg05368731 chr17:41323189 NBR1 -1.16 -14.14 -0.79 1.28e-27 Menopause (age at onset); TGCT cis rs644799 1.000 rs10831431 chr11:95510089 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 11.08 0.71 2.9e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1997103 0.954 rs940880 chr7:55392619 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.22 -0.42 7.39e-7 Bipolar disorder; TGCT cis rs7226408 0.948 rs72885219 chr18:34400995 A/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs7552404 0.731 rs10732723 chr1:76392437 C/T cg03433033 chr1:76189801 ACADM -0.75 -7.61 -0.56 5.97e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10876993 0.890 rs1678516 chr12:58047458 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs6964587 1.000 rs2299232 chr7:91626699 A/C cg22709100 chr7:91322751 NA 0.27 4.46 0.37 1.84e-5 Breast cancer; TGCT cis rs11785400 0.701 rs9297968 chr8:143723009 A/G cg10596483 chr8:143751796 JRK 0.53 5.23 0.43 7.02e-7 Schizophrenia; TGCT cis rs1215050 0.740 rs783949 chr4:99001933 A/G cg17366294 chr4:99064904 C4orf37 -0.54 -5.81 -0.46 4.85e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2956278 0.678 rs10161501 chr12:84685594 A/G cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2688608 1.000 rs2675680 chr10:75658864 T/C cg02947784 chr10:75434997 AGAP5 0.16 4.52 0.38 1.4e-5 Inflammatory bowel disease; TGCT cis rs11252926 0.599 rs11252213 chr10:454694 C/T cg13477178 chr10:375248 DIP2C -0.24 -4.46 -0.37 1.82e-5 Psychosis in Alzheimer's disease; TGCT cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.53 -4.6 -0.38 1.02e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 0.910 rs7617361 chr3:40373259 G/T cg17264618 chr3:40429014 ENTPD3 0.3 4.47 0.37 1.72e-5 Renal cell carcinoma; TGCT cis rs2197308 0.740 rs1842595 chr12:37906223 G/A cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs2201728 0.935 rs1497378 chr4:100158023 T/G cg07219303 chr4:100140905 ADH6 -0.35 -5.22 -0.42 7.29e-7 Cardiac Troponin-T levels; TGCT cis rs1790761 0.501 rs4930210 chr11:67404726 G/T cg00864171 chr11:67383662 NA -0.33 -5.08 -0.41 1.35e-6 Mean corpuscular volume; TGCT cis rs5769707 0.935 rs739239 chr22:50050468 G/A cg05373962 chr22:49881684 NA -0.32 -6.56 -0.51 1.34e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs922182 0.547 rs12594348 chr15:64269127 C/T cg02919090 chr15:64263738 DAPK2 -0.27 -4.77 -0.39 5.12e-6 Blood protein levels; TGCT trans rs7618501 1.000 rs9872864 chr3:49792023 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs7657179 chr4:98948569 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs807669 0.903 rs1780640 chr22:19174597 C/T cg02655711 chr22:19163373 SLC25A1 0.42 10.11 0.67 6.78e-18 Metabolite levels; TGCT cis rs801193 1.000 rs2707836 chr7:66160435 A/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs13392177 0.660 rs62185964 chr2:219073745 A/G cg00012203 chr2:219082015 ARPC2 -0.79 -8.02 -0.58 6.73e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs926938 0.527 rs360678 chr1:115493902 T/A cg12756093 chr1:115239321 AMPD1 0.34 4.96 0.41 2.28e-6 Autism; TGCT cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.82 0.46 4.65e-8 Bipolar disorder; TGCT cis rs765787 0.530 rs4331289 chr15:45515338 C/T cg24006582 chr15:45444508 DUOX1 -0.26 -5.59 -0.45 1.35e-7 Uric acid levels; TGCT cis rs7617773 0.539 rs12486944 chr3:48390016 G/A cg11946769 chr3:48343235 NME6 0.57 4.89 0.4 3.05e-6 Coronary artery disease; TGCT cis rs7829975 0.846 rs1879957 chr8:8544808 T/C cg15556689 chr8:8085844 FLJ10661 -0.69 -6.12 -0.48 1.11e-8 Mood instability; TGCT cis rs2013441 1.000 rs2703774 chr17:20133538 C/T cg18979559 chr17:20280153 CCDC144C -0.45 -4.59 -0.38 1.08e-5 Obesity-related traits; TGCT cis rs13217239 0.646 rs7451149 chr6:27057518 A/G cg05738196 chr6:26577821 NA -0.48 -4.62 -0.38 9.5e-6 Schizophrenia; TGCT cis rs4332037 0.539 rs56016347 chr7:2060126 C/T cg25834613 chr7:1915315 MAD1L1 -0.51 -4.99 -0.41 1.95e-6 Bipolar disorder; TGCT cis rs289997 1.000 rs2938108 chr7:25584697 C/T cg14064488 chr7:26331273 SNX10 -0.34 -4.74 -0.39 5.83e-6 Breast cancer; TGCT cis rs10484885 0.775 rs72919985 chr6:90534641 A/G cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs319204 0.885 rs319184 chr5:146272865 T/G cg25021259 chr5:146258546 PPP2R2B 0.34 4.47 0.37 1.75e-5 Schizophrenia; TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg24503407 chr1:205819492 PM20D1 0.59 8.15 0.59 3.41e-13 Menarche (age at onset); TGCT cis rs2836974 0.644 rs1882779 chr21:40690938 T/C cg11890956 chr21:40555474 PSMG1 -0.75 -6.78 -0.52 4.36e-10 Cognitive function; TGCT trans rs4710191 0.510 rs2180713 chr6:167615010 G/A cg04222842 chr1:225965391 SRP9 0.61 6.66 0.51 8.01e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs262150 0.625 rs55882200 chr7:158769280 G/C cg01219135 chr7:158766336 NA -0.51 -5.34 -0.43 4.25e-7 Facial morphology (factor 20); TGCT cis rs644799 1.000 rs617999 chr11:95589935 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.88 10.59 0.69 4.58e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs4650994 0.816 rs2093770 chr1:178604633 C/A cg05059571 chr16:84539110 KIAA1609 0.41 7.63 0.57 5.38e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs11209002 0.614 rs7519768 chr1:67555522 C/T cg02640540 chr1:67518911 SLC35D1 0.56 4.66 0.39 8.05e-6 Crohn's disease; TGCT cis rs2013441 1.000 rs2703774 chr17:20133538 C/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.44 -0.37 1.99e-5 Obesity-related traits; TGCT cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg13732083 chr21:47605072 C21orf56 0.33 4.48 0.37 1.7e-5 Testicular germ cell tumor; TGCT cis rs28595532 0.920 rs116231457 chr4:119762396 A/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs4555082 0.718 rs2816619 chr14:105732551 G/C cg01266790 chr14:105781312 PACS2 0.56 4.6 0.38 1.04e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs6665290 0.904 rs6426559 chr1:227195876 T/C cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs2224391 0.590 rs9405813 chr6:5251850 G/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.96 -5.44 -0.44 2.67e-7 Height; TGCT cis rs12477438 0.520 rs2969379 chr2:99776686 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.31 0.77 1.16e-25 Chronic sinus infection; TGCT cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg20637647 chr7:64974828 NA 0.88 5.12 0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs56309584 0.673 rs11658322 chr17:8171329 T/C cg08322244 chr17:8066669 VAMP2 -0.57 -5.31 -0.43 4.89e-7 Initial pursuit acceleration; TGCT cis rs2562456 0.837 rs11085462 chr19:21750251 C/G cg01304269 chr19:21688519 ZNF429 0.58 4.73 0.39 5.93e-6 Pain; TGCT cis rs3820068 0.580 rs7556473 chr1:15996858 C/T cg05660106 chr1:15850417 CASP9 -0.67 -6.02 -0.48 1.86e-8 Systolic blood pressure; TGCT cis rs9467773 0.526 rs10946817 chr6:26364056 C/T cg15659132 chr6:26577336 NA -0.5 -5.05 -0.41 1.53e-6 Intelligence (multi-trait analysis); TGCT cis rs7731657 0.537 rs17621442 chr5:130205555 T/C cg08523029 chr5:130500466 HINT1 -0.59 -4.9 -0.4 2.87e-6 Fasting plasma glucose; TGCT cis rs950880 0.560 rs11685424 chr2:102926981 G/A cg09003973 chr2:102972529 NA -0.54 -4.72 -0.39 6.3e-6 Serum protein levels (sST2); TGCT cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.73e-7 Menopause (age at onset); TGCT cis rs2576037 0.583 rs578451 chr18:44404525 T/A cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.61 -0.38 9.88e-6 Personality dimensions; TGCT cis rs114540395 0.858 rs77691531 chr10:103123526 G/A cg18276125 chr10:102749041 C10orf2 0.36 4.44 0.37 1.98e-5 Schizophrenia; TGCT cis rs6121246 0.512 rs45443696 chr20:30311396 A/C cg10886678 chr20:30946050 ASXL1 -0.57 -4.83 -0.4 3.98e-6 Mean corpuscular hemoglobin; TGCT cis rs78487399 0.808 rs7599799 chr2:43685493 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.77 0.39 5.16e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7601155 1.000 rs7601155 chr2:28347682 C/T cg09958967 chr2:27485780 SLC30A3 0.9 4.76 0.39 5.35e-6 Waist circumference; TGCT cis rs36051895 0.589 rs16922772 chr9:5194521 C/A cg02405213 chr9:5042618 JAK2 -0.73 -9.46 -0.65 2.62e-16 Pediatric autoimmune diseases; TGCT cis rs6089584 0.888 rs6061405 chr20:60617033 A/G cg13665807 chr20:60559372 TAF4 -0.46 -5.0 -0.41 1.92e-6 Body mass index; TGCT cis rs2251381 0.565 rs2832279 chr21:30613466 G/T cg24692254 chr21:30365293 RNF160 0.58 5.37 0.43 3.66e-7 Selective IgA deficiency; TGCT cis rs10883723 0.810 rs3740406 chr10:104272789 C/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs11648796 0.879 rs12448432 chr16:778820 G/A cg27436995 chr16:743998 FBXL16 -0.51 -4.44 -0.37 1.96e-5 Height; TGCT cis rs4824093 0.610 rs4824113 chr22:50284974 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.13 -6.81 -0.52 3.83e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs5744897 0.708 rs5744769 chr12:133250734 C/G cg17341477 chr12:133246679 POLE 0.39 4.98 0.41 2.05e-6 Urate levels in overweight individuals; TGCT cis rs1865760 0.929 rs9358896 chr6:25943197 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.15 0.48 9.65e-9 Height; TGCT trans rs11088226 0.681 rs2833902 chr21:33940458 A/G cg09050820 chr6:167586206 TCP10L2 0.8 7.19 0.54 5.26e-11 Gastritis; TGCT trans rs561341 0.941 rs8081016 chr17:30331751 A/G cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs589448 0.900 rs588493 chr12:69751986 G/A cg14784868 chr12:69753453 YEATS4 0.89 10.43 0.68 1.11e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs10751667 1.000 rs4074232 chr11:977682 C/G cg06064525 chr11:970664 AP2A2 -0.33 -6.51 -0.5 1.71e-9 Alzheimer's disease (late onset); TGCT cis rs2013441 1.000 rs2386429 chr17:20210809 G/A cg18979559 chr17:20280153 CCDC144C -0.49 -5.0 -0.41 1.88e-6 Obesity-related traits; TGCT cis rs7552404 1.000 rs12127402 chr1:76205643 C/A cg03433033 chr1:76189801 ACADM 0.82 9.74 0.66 5.46e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg23205692 chr1:25664452 TMEM50A -0.51 -5.22 -0.42 7.4e-7 Erythrocyte sedimentation rate; TGCT cis rs8103278 0.507 rs16939 chr19:46276056 C/A cg11657440 chr19:46296263 DMWD 0.75 8.06 0.59 5.37e-13 Coronary artery disease; TGCT cis rs858239 0.730 rs858289 chr7:23248158 C/T cg05602783 chr7:23145260 KLHL7 -0.64 -5.39 -0.44 3.41e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2153535 0.580 rs7341206 chr6:8470489 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7655841 0.704 rs789982 chr4:129999071 T/C cg26347359 chr4:129759716 PHF17 -0.44 -4.97 -0.41 2.16e-6 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs11685299 1 rs11685299 chr2:225391296 C/A cg12698349 chr2:225449008 CUL3 0.98 9.44 0.65 2.87e-16 Schizophrenia; TGCT cis rs3126085 0.935 rs11204981 chr1:152298212 C/T cg03465714 chr1:152285911 FLG 0.41 4.67 0.39 7.63e-6 Atopic dermatitis; TGCT cis rs3087591 0.639 rs1048317 chr17:29704002 T/C cg24425628 chr17:29625626 OMG;NF1 0.36 5.06 0.41 1.47e-6 Hip circumference; TGCT cis rs2130392 0.962 rs13132498 chr4:185611454 T/C cg14471096 chr4:185570637 CCDC111;CASP3 -0.55 -4.99 -0.41 1.97e-6 Kawasaki disease; TGCT cis rs6089584 0.586 rs4925216 chr20:60599923 G/A cg13770153 chr20:60521292 NA -0.41 -5.0 -0.41 1.88e-6 Body mass index; TGCT trans rs3102947 0.539 rs1473233 chr2:8499766 C/T cg01718733 chr15:29409410 APBA2 0.31 6.79 0.52 4.09e-10 IgE levels; TGCT cis rs2404602 0.735 rs12906143 chr15:76709523 T/A cg26408565 chr15:76604113 ETFA 0.38 4.49 0.37 1.58e-5 Blood metabolite levels; TGCT cis rs4843185 0.669 rs889502 chr16:85716832 A/G cg06784122 chr16:85688175 KIAA0182 0.27 4.47 0.37 1.72e-5 Platelet distribution width; TGCT cis rs986417 1.000 rs2351175 chr14:61066730 C/T cg27398547 chr14:60952738 C14orf39 1.49 9.97 0.67 1.46e-17 Gut microbiota (bacterial taxa); TGCT cis rs2933343 0.729 rs6767104 chr3:128648117 G/T cg11901034 chr3:128598214 ACAD9 0.66 6.45 0.5 2.3e-9 IgG glycosylation; TGCT cis rs4148883 0.713 rs3828541 chr4:100042262 A/G cg12011299 chr4:100065546 ADH4 0.36 5.36 0.43 3.85e-7 Alcohol dependence; TGCT cis rs425277 0.958 rs7546523 chr1:2043792 G/A cg03732007 chr1:2071316 PRKCZ 0.24 4.65 0.39 8.46e-6 Height; TGCT cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg04546413 chr19:29218101 NA 0.84 6.82 0.52 3.52e-10 Methadone dose in opioid dependence; TGCT cis rs13256369 1.000 rs9329165 chr8:8576642 C/T cg06671706 chr8:8559999 CLDN23 -0.36 -4.88 -0.4 3.15e-6 Obesity-related traits; TGCT cis rs61990749 0.597 rs1978416 chr14:78227901 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs2204008 0.628 rs10876106 chr12:37990767 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.89 0.4 3.05e-6 Bladder cancer; TGCT cis rs137603 1.000 rs137604 chr22:39694594 C/G cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -5.12 -0.42 1.13e-6 Primary biliary cholangitis; TGCT cis rs1215050 0.755 rs9991112 chr4:98651479 A/C cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7940866 0.801 rs10894300 chr11:130845943 A/G cg05962950 chr11:130786565 SNX19 0.73 7.14 0.54 6.99e-11 Schizophrenia; TGCT cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg03264133 chr6:25882463 NA -0.53 -5.53 -0.44 1.81e-7 Blood metabolite levels; TGCT cis rs28595532 0.920 rs116799007 chr4:119763562 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg03303774 chr4:1407052 NA 0.32 4.73 0.39 6.03e-6 Obesity-related traits; TGCT cis rs6499129 0.558 rs7203742 chr16:67605794 A/G cg03412735 chr16:68482518 SMPD3 0.64 4.44 0.37 1.93e-5 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7582180 0.629 rs4851294 chr2:100941109 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.86 -0.4 3.49e-6 Intelligence (multi-trait analysis); TGCT cis rs4665809 1.000 rs6546766 chr2:26328680 T/C cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg03806693 chr22:41940476 POLR3H -1.14 -13.38 -0.77 8.05e-26 Vitiligo; TGCT cis rs9300255 0.602 rs2682434 chr12:123694724 C/T cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT trans rs17685 0.671 rs10274404 chr7:75706634 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 8.99 0.63 3.49e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2404602 0.647 rs8025991 chr15:77155268 C/T cg23625390 chr15:77176239 SCAPER -0.39 -5.15 -0.42 9.85e-7 Blood metabolite levels; TGCT cis rs9916302 0.706 rs4332770 chr17:37704712 T/C cg03321784 chr17:37729644 NA 0.44 4.58 0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs259282 0.707 rs1103851 chr19:33146414 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.79 7.63 0.57 5.27e-12 Schizophrenia; TGCT cis rs2688608 0.869 rs2250140 chr10:75612881 T/C cg04320760 chr10:75533139 FUT11 -0.31 -4.65 -0.39 8.27e-6 Inflammatory bowel disease; TGCT trans rs28735056 0.587 rs8093548 chr18:77636451 G/A cg05926928 chr17:57297772 GDPD1 -0.83 -9.64 -0.65 9.38e-17 Schizophrenia; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg08736216 chr1:53307985 ZYG11A 0.28 5.65 0.45 1.03e-7 Monocyte count; TGCT cis rs2663905 0.664 rs2460855 chr15:81361729 G/T cg09236163 chr15:81426669 C15orf26 -0.46 -4.55 -0.38 1.27e-5 QT interval (drug interaction); TGCT cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs7582180 0.629 rs11684516 chr2:100949883 C/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs1843834 0.858 rs12105685 chr2:225513164 A/G cg22455342 chr2:225449267 CUL3 0.73 7.31 0.55 2.88e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs875971 1.000 rs811880 chr7:65818646 T/C cg11764359 chr7:65958608 NA 0.62 5.53 0.44 1.82e-7 Aortic root size; TGCT cis rs7917772 0.582 rs3977756 chr10:104398582 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.28 -0.43 5.48e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12497850 0.931 rs9311432 chr3:48850443 T/A cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs3125734 0.633 rs10821968 chr10:63993905 C/T cg19640130 chr10:64028056 RTKN2 0.39 5.11 0.42 1.21e-6 Rheumatoid arthritis; TGCT cis rs12541335 0.639 rs3923439 chr8:22170079 G/A cg02463440 chr8:22132932 PIWIL2 0.26 5.09 0.42 1.29e-6 Hypertriglyceridemia; TGCT cis rs3812831 0.635 rs6560937 chr13:114945991 C/G cg08824895 chr13:115047677 UPF3A 0.49 4.76 0.39 5.26e-6 Schizophrenia; TGCT cis rs9381040 0.655 rs879491 chr6:41026953 A/G cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg03806693 chr22:41940476 POLR3H -1.01 -11.18 -0.71 1.71e-20 Vitiligo; TGCT cis rs612683 0.759 rs12722868 chr1:100956478 A/G cg06223162 chr1:101003688 GPR88 0.32 4.98 0.41 2.1e-6 Breast cancer; TGCT cis rs1942 0.742 rs1655558 chr15:41787585 T/G cg18705301 chr15:41695430 NDUFAF1 -0.45 -5.9 -0.47 3.28e-8 Eosinophil percentage of granulocytes; TGCT trans rs208520 0.874 rs208514 chr6:66945520 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.93 -0.67 1.84e-17 Exhaled nitric oxide output; TGCT cis rs3540 0.533 rs2352601 chr15:91053125 G/A cg22089800 chr15:90895588 ZNF774 -0.76 -7.96 -0.58 9.24e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs459571 1.000 rs456207 chr9:136911140 G/A cg13789015 chr9:136890014 NCRNA00094 0.39 6.81 0.52 3.72e-10 Platelet distribution width; TGCT cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.59 -5.43 -0.44 2.87e-7 Height; TGCT cis rs7829975 0.511 rs2976906 chr8:8342415 A/T cg06636001 chr8:8085503 FLJ10661 0.61 5.69 0.46 8.54e-8 Mood instability; TGCT cis rs57920188 0.585 rs12117500 chr1:4072315 G/A cg20703997 chr1:4087676 NA 0.47 5.8 0.46 5.14e-8 Interleukin-17 levels; TGCT cis rs7572733 0.534 rs700692 chr2:198728500 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs17826219 0.706 rs8075357 chr17:29057197 A/C cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Body mass index; TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs7258465 0.965 rs748609 chr19:18560282 T/C cg06462663 chr19:18546047 ISYNA1 0.2 4.5 0.37 1.56e-5 Breast cancer; TGCT cis rs7432375 0.580 rs4678441 chr3:136532828 T/C cg15507776 chr3:136538369 TMEM22 0.55 5.63 0.45 1.15e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs2227564 0.620 rs4746148 chr10:75534488 C/T cg04320760 chr10:75533139 FUT11 -0.31 -4.49 -0.37 1.64e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6671200 1.000 rs12755552 chr1:95685026 A/G cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs2562456 0.755 rs2650773 chr19:21644088 A/G cg01304269 chr19:21688519 ZNF429 -0.6 -4.89 -0.4 3.07e-6 Pain; TGCT cis rs3782455 1.000 rs117470230 chr12:114403053 G/C cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg11494091 chr17:61959527 GH2 0.43 7.3 0.55 3.05e-11 Height; TGCT cis rs77861329 1.000 rs352153 chr3:52211184 A/T cg08692210 chr3:52188851 WDR51A 0.9 4.85 0.4 3.66e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs9341808 0.935 rs9448894 chr6:80837253 G/T cg08355045 chr6:80787529 NA 0.28 4.98 0.41 2.11e-6 Sitting height ratio; TGCT cis rs10992471 0.528 rs6479423 chr9:95265580 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.51 -4.81 -0.4 4.31e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs17376456 0.877 rs12374488 chr5:93481407 A/G cg21475434 chr5:93447410 FAM172A 0.63 4.63 0.38 8.98e-6 Diabetic retinopathy; TGCT cis rs2072499 1.000 rs2253809 chr1:156172125 T/C cg24450063 chr1:156163899 SLC25A44 1.17 17.33 0.84 6.21e-35 Testicular germ cell tumor; TGCT cis rs7324557 0.717 rs9507164 chr13:24380539 A/G cg16602799 chr13:25254742 ATP12A 0.57 4.45 0.37 1.93e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs4886920 0.563 rs4511491 chr15:78079304 A/G cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.36e-6 Neuroticism; TGCT cis rs727505 0.721 rs67607629 chr7:124765867 C/T cg23710748 chr7:124431027 NA -0.25 -4.63 -0.38 9.13e-6 Lewy body disease; TGCT cis rs9611565 0.571 rs7364123 chr22:42216326 A/G cg06481639 chr22:41940642 POLR3H -0.53 -4.46 -0.37 1.81e-5 Vitiligo; TGCT cis rs6671200 0.607 rs2147587 chr1:95714884 G/A cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs7659604 0.628 rs3828485 chr4:122722368 G/A cg19748678 chr4:122722346 EXOSC9 0.94 9.97 0.67 1.5e-17 Type 2 diabetes; TGCT cis rs61990749 0.597 rs12887606 chr14:78200620 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg20302342 chr1:156215951 PAQR6 0.36 5.38 0.44 3.56e-7 Tonsillectomy; TGCT cis rs7647973 0.626 rs9870858 chr3:49769071 C/T cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs10782582 0.609 rs11584577 chr1:76242378 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.51 4.59 0.38 1.06e-5 Daytime sleep phenotypes; TGCT cis rs1333657 0.782 rs13217528 chr6:10295896 A/C cg24286789 chr6:10417726 TFAP2A -0.27 -4.52 -0.38 1.43e-5 Orofacial clefts; TGCT cis rs9902453 0.967 rs9904336 chr17:28357080 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs644799 0.965 rs502521 chr11:95533557 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6969780 0.915 rs12666919 chr7:27189498 A/T cg04321618 chr7:27170880 HOXA4 -0.51 -4.45 -0.37 1.86e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs56104184 0.775 rs73061697 chr19:49400000 C/T cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg21280719 chr6:42927975 GNMT -0.37 -4.56 -0.38 1.22e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg14983838 chr19:29218262 NA 0.76 6.92 0.53 2.11e-10 Methadone dose in opioid dependence; TGCT cis rs7267979 1.000 rs7267979 chr20:25298087 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2777491 0.915 rs28578057 chr15:41621921 G/A cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.44 -0.68 1.07e-18 Ulcerative colitis; TGCT cis rs2033711 0.870 rs7408188 chr19:58939389 T/G cg12042659 chr19:58951599 ZNF132 0.51 4.66 0.39 7.97e-6 Uric acid clearance; TGCT trans rs12339966 0.653 rs10733233 chr9:11298203 T/A cg07173112 chr1:1114698 TTLL10 -0.34 -6.86 -0.52 2.97e-10 Systolic blood pressure; TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs6500602 0.893 rs8061742 chr16:4489436 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.19 0.42 8.41e-7 Schizophrenia; TGCT cis rs9303401 0.659 rs34468504 chr17:56648277 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg03161606 chr19:29218774 NA 0.62 6.0 0.47 2e-8 Methadone dose in opioid dependence; TGCT cis rs6490294 0.687 rs648300 chr12:112175819 C/G cg10833066 chr12:111807467 FAM109A 0.32 4.96 0.41 2.25e-6 Mean platelet volume; TGCT cis rs6754311 0.589 rs749873 chr2:136817088 C/T cg07169764 chr2:136633963 MCM6 -0.56 -5.48 -0.44 2.29e-7 Mosquito bite size; TGCT cis rs670523 0.722 rs4661079 chr1:155983298 A/G cg05700447 chr1:155978627 NA -0.19 -4.79 -0.39 4.75e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs704 0.739 rs733914 chr17:26671196 C/G cg10342447 chr17:26645325 TMEM97 -0.55 -5.2 -0.42 7.94e-7 Osteoprotegerin levels; TGCT cis rs68170813 0.559 rs12537785 chr7:107050221 T/C cg02696742 chr7:106810147 HBP1 -0.71 -5.9 -0.47 3.17e-8 Coronary artery disease; TGCT cis rs17376456 0.877 rs13185660 chr5:93336500 G/A cg09848695 chr5:92956644 FAM172A;MIR2277 0.62 4.44 0.37 1.98e-5 Diabetic retinopathy; TGCT cis rs1153858 1.000 rs2467864 chr15:45641098 C/T cg26924012 chr15:45694286 SPATA5L1 -0.97 -11.62 -0.72 1.44e-21 Homoarginine levels; TGCT cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs10883723 0.810 rs12265877 chr10:104247247 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs240110 0.515 rs12530388 chr6:101329173 A/C cg09795085 chr6:101329169 ASCC3 0.6 4.89 0.4 3.01e-6 Neuroticism; TGCT cis rs35883536 0.647 rs17402630 chr1:101046587 C/T cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.74 -0.39 5.77e-6 Prudent dietary pattern; TGCT cis rs910316 0.967 rs2024653 chr14:75595154 G/A cg23033748 chr14:75592666 NEK9 0.29 4.9 0.4 2.95e-6 Height; TGCT cis rs1552244 0.515 rs7613004 chr3:9999913 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.31 -4.82 -0.4 4.12e-6 Alzheimer's disease; TGCT cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg21724239 chr8:58056113 NA 0.44 4.57 0.38 1.18e-5 Developmental language disorder (linguistic errors); TGCT cis rs709400 0.567 rs11624343 chr14:103859156 T/A cg12935359 chr14:103987150 CKB -0.36 -5.38 -0.43 3.63e-7 Body mass index; TGCT cis rs7439150 1.000 rs2227401 chr4:155486381 C/T cg22130008 chr4:155548532 NA -0.47 -5.8 -0.46 5.25e-8 Fibrinogen levels; TGCT cis rs7264396 0.677 rs6060553 chr20:34267386 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.87e-7 Total cholesterol levels; TGCT cis rs4455778 0.580 rs6970665 chr7:49124091 T/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs2180341 0.960 rs7745944 chr6:127709574 A/G cg24812749 chr6:127587940 RNF146 0.98 7.53 0.56 9.29e-12 Breast cancer; TGCT cis rs6088590 1.000 rs6087632 chr20:33407704 A/C cg24642439 chr20:33292090 TP53INP2 0.68 6.09 0.48 1.32e-8 Coronary artery disease; TGCT cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg05738196 chr6:26577821 NA 0.87 10.82 0.7 1.29e-19 Intelligence (multi-trait analysis); TGCT cis rs2180341 1.000 rs2180341 chr6:127600630 C/T cg27446573 chr6:127587934 RNF146 1.12 10.04 0.67 1.02e-17 Breast cancer; TGCT cis rs28595532 0.920 rs115744897 chr4:119749064 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs210152 0.588 rs449978 chr6:33496060 G/A cg07735790 chr6:34101545 GRM4 -0.52 -4.79 -0.4 4.68e-6 Schizophrenia; TGCT cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs7772486 0.686 rs857875 chr6:145980033 T/G cg05347473 chr6:146136440 FBXO30 -0.47 -4.45 -0.37 1.9e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 0.628 rs4949686 chr1:76473299 G/C cg03433033 chr1:76189801 ACADM 0.77 6.8 0.52 3.85e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6519955 0.765 rs7292527 chr22:46423125 G/T cg05468064 chr22:46423449 NA -0.57 -5.92 -0.47 2.88e-8 Dupuytren's disease; TGCT cis rs3806843 0.607 rs246060 chr5:140324749 T/C cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7191700 0.509 rs416603 chr16:11364079 A/T cg00044050 chr16:11439710 C16orf75 -0.65 -6.15 -0.48 9.84e-9 Multiple sclerosis; TGCT cis rs7552404 0.883 rs11161493 chr1:76206254 T/A cg10523679 chr1:76189770 ACADM 0.89 9.88 0.66 2.42e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7249142 0.597 rs759999 chr19:19281207 A/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.33 -4.52 -0.38 1.42e-5 IgG glycosylation; TGCT cis rs875971 1.000 rs3735148 chr7:65971009 T/G cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs1018836 0.608 rs7821069 chr8:91465548 C/G cg16814680 chr8:91681699 NA -0.71 -7.16 -0.54 6.36e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs11098499 0.909 rs79026312 chr4:120440677 C/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs8014204 0.935 rs1799900 chr14:75367740 G/A cg06637938 chr14:75390232 RPS6KL1 -0.73 -6.94 -0.53 1.96e-10 Caffeine consumption; TGCT cis rs7324557 0.717 rs9510869 chr13:24384129 C/T cg16602799 chr13:25254742 ATP12A 0.57 4.45 0.37 1.93e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs9318086 0.648 rs7331047 chr13:24467342 T/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.83 9.04 0.63 2.62e-15 Myopia (pathological); TGCT cis rs244731 0.959 rs7721671 chr5:176630984 A/G cg17509989 chr5:176798049 RGS14 -0.6 -7.32 -0.55 2.69e-11 Urate levels in lean individuals; TGCT cis rs76473307 1.000 rs6026540 chr20:57391435 A/G cg06163629 chr20:57414884 GNASAS;GNAS -0.66 -4.53 -0.38 1.39e-5 Chronic lymphocytic leukemia; TGCT cis rs208520 0.754 rs12204635 chr6:66740779 C/A cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs13108904 0.901 rs12509700 chr4:1296321 A/G cg03303774 chr4:1407052 NA 0.32 4.73 0.39 6.03e-6 Obesity-related traits; TGCT cis rs1577917 0.958 rs67024565 chr6:86553997 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.42 -0.44 3.02e-7 Response to antipsychotic treatment; TGCT cis rs11943027 0.840 rs10034699 chr4:38835868 A/T cg02016764 chr4:38805732 TLR1 -0.26 -4.46 -0.37 1.85e-5 Alcohol dependence; TGCT cis rs12477438 0.765 rs9710648 chr2:99673129 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs35306767 0.903 rs12244355 chr10:944465 T/C cg20503657 chr10:835505 NA 0.75 10.55 0.69 5.67e-19 Eosinophil percentage of granulocytes; TGCT trans rs17685 0.712 rs28506984 chr7:75763484 A/G cg19862616 chr7:65841803 NCRNA00174 0.51 8.59 0.61 3.07e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs208520 0.661 rs1100950 chr6:66827285 A/C cg07460842 chr6:66804631 NA -0.95 -9.74 -0.66 5.26e-17 Exhaled nitric oxide output; TGCT cis rs2506155 0.838 rs2474713 chr10:33497150 A/C cg25928881 chr10:32632685 EPC1 0.28 4.47 0.37 1.77e-5 Migraine; TGCT cis rs1218582 0.741 rs883718 chr1:154846274 C/T cg06221963 chr1:154839813 KCNN3 -0.75 -13.71 -0.78 1.3e-26 Prostate cancer; TGCT cis rs2236918 0.710 rs2526702 chr1:242017983 G/A cg04158730 chr1:242011433 EXO1 0.58 5.47 0.44 2.42e-7 Menopause (age at onset); TGCT cis rs68170813 0.559 rs4730229 chr7:106925353 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg15659132 chr6:26577336 NA 0.83 10.06 0.67 9.18e-18 Intelligence (multi-trait analysis); TGCT cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.07 0.41 1.4e-6 Height; TGCT cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 4.99 0.41 1.98e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9894429 0.752 rs7502883 chr17:79588557 T/C cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.22e-10 Eye color traits; TGCT cis rs3008870 1.000 rs11208979 chr1:67442275 C/T cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs916888 0.610 rs199530 chr17:44836653 C/T cg15921436 chr17:44337874 NA -0.39 -6.06 -0.48 1.51e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.15 10.22 0.68 3.75e-18 Platelet count; TGCT cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg21782813 chr7:2030301 MAD1L1 0.32 4.58 0.38 1.12e-5 Bipolar disorder and schizophrenia; TGCT cis rs8180040 0.966 rs12486969 chr3:47429003 G/C cg27129171 chr3:47204927 SETD2 -0.64 -7.39 -0.55 1.89e-11 Colorectal cancer; TGCT cis rs3125734 0.660 rs10733769 chr10:63974255 G/T cg09941381 chr10:64027924 RTKN2 -0.36 -5.38 -0.44 3.55e-7 Rheumatoid arthritis; TGCT cis rs636291 0.517 rs12565133 chr1:10544988 A/C cg17425144 chr1:10567563 PEX14 -0.51 -7.42 -0.55 1.66e-11 Prostate cancer; TGCT trans rs7726839 0.561 rs72703044 chr5:579737 G/A cg11887960 chr12:57824829 NA 0.96 8.01 0.58 7.22e-13 Obesity-related traits; TGCT cis rs308403 0.568 rs309344 chr4:123644812 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.72 6.64 0.51 8.74e-10 Blood protein levels; TGCT cis rs7226408 0.857 rs11081989 chr18:34713367 A/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs929596 0.785 rs6714634 chr2:234664765 C/T cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 0.31 4.86 0.4 3.45e-6 Total bilirubin levels in HIV-1 infection; TGCT cis rs10832963 1.000 rs10832956 chr11:18645668 A/G cg20219074 chr11:18656078 SPTY2D1 0.98 10.07 0.67 8.69e-18 Breast cancer; TGCT cis rs832540 0.931 rs33318 chr5:56208414 G/T cg12311346 chr5:56204834 C5orf35 -0.48 -5.14 -0.42 1.06e-6 Coronary artery disease; TGCT cis rs12776158 0.901 rs57805780 chr10:71216455 A/C cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs12048904 0.541 rs6699536 chr1:101276544 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.82 7.43 0.56 1.5e-11 Multiple sclerosis; TGCT cis rs1348850 0.914 rs1348849 chr2:178358072 C/T cg22681709 chr2:178499509 PDE11A -0.35 -4.53 -0.38 1.39e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9790314 0.502 rs7647118 chr3:161016165 T/C cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Morning vs. evening chronotype; TGCT cis rs4319547 0.695 rs4758662 chr12:122924778 G/A cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.38 -0.44 3.58e-7 Body mass index; TGCT cis rs3947 0.855 rs1293327 chr8:11694986 G/A cg02840367 chr8:11660030 FDFT1 0.89 6.56 0.51 1.3e-9 Blood protein levels; TGCT cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg19318889 chr4:1322082 MAEA -0.27 -6.51 -0.5 1.69e-9 Longevity; TGCT cis rs4665809 1.000 rs6749855 chr2:26255263 A/G cg22920501 chr2:26401640 FAM59B -0.71 -6.11 -0.48 1.21e-8 Gut microbiome composition (summer); TGCT cis rs3087591 0.960 rs2905790 chr17:29476110 A/G cg24425628 chr17:29625626 OMG;NF1 0.46 7.23 0.54 4.3e-11 Hip circumference; TGCT cis rs11690935 0.959 rs7572215 chr2:172634228 G/A cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs9325144 0.532 rs1352121 chr12:39130696 A/G cg26384229 chr12:38710491 ALG10B -0.62 -5.85 -0.47 4.06e-8 Morning vs. evening chronotype; TGCT cis rs174449 0.603 rs174460 chr11:61657110 C/T cg01500311 chr11:61656094 FADS3 0.35 6.7 0.52 6.49e-10 Trans fatty acid levels; TGCT cis rs739496 0.527 rs10774639 chr12:112258445 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs4727027 0.933 rs12704063 chr7:148827909 T/C cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg22618164 chr12:122356400 WDR66 0.64 6.46 0.5 2.15e-9 Mean corpuscular volume; TGCT cis rs2404602 0.647 rs11637096 chr15:76931102 T/C cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs10949834 0.793 rs810532 chr7:73505188 A/G cg07137043 chr7:73588983 EIF4H -0.61 -4.61 -0.38 9.71e-6 Verbal memory performance (residualized delayed recall change); TGCT cis rs12477438 0.798 rs9808541 chr2:99642179 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs1371867 0.846 rs1788181 chr8:101334068 C/T cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs2120019 1.000 rs34237279 chr15:75361121 A/G cg17294928 chr15:75287854 SCAMP5 -0.84 -6.34 -0.5 3.8e-9 Blood trace element (Zn levels); TGCT cis rs9611565 0.614 rs4822053 chr22:42212936 C/A cg03806693 chr22:41940476 POLR3H -0.85 -8.06 -0.59 5.38e-13 Vitiligo; TGCT cis rs797680 0.856 rs2031226 chr1:93786764 G/T cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs60843830 1.000 rs7566279 chr2:281178 C/G cg25945732 chr2:264204 ACP1;SH3YL1 0.72 7.12 0.54 7.7e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1018836 0.851 rs6986359 chr8:91643162 A/G cg16814680 chr8:91681699 NA -0.8 -8.6 -0.61 2.89e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs17345786 0.906 rs59359251 chr3:101146362 A/C cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs7020830 0.861 rs2291589 chr9:37079661 T/G cg14294708 chr9:37120828 ZCCHC7 1.29 20.57 0.88 8.64e-42 Schizophrenia; TGCT cis rs854765 0.547 rs7212167 chr17:17913504 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.27 0.6 1.72e-13 Total body bone mineral density; TGCT trans rs1814175 0.817 rs10769648 chr11:50013992 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs2204008 0.560 rs1315354 chr12:38165716 A/G cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.32e-6 Bladder cancer; TGCT cis rs9644630 0.965 rs10105097 chr8:19364883 A/C cg01280390 chr8:19363452 CSGALNACT1 -0.27 -4.68 -0.39 7.47e-6 Oropharynx cancer; TGCT trans rs10504390 0.656 rs77264178 chr8:66515086 G/A cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.29e-10 IgG glycosylation; TGCT cis rs7769051 1.000 rs5006218 chr6:133126220 T/G cg22852734 chr6:133119734 C6orf192 1.23 7.09 0.54 9.13e-11 Type 2 diabetes nephropathy; TGCT cis rs12479064 0.505 rs62153764 chr2:99818612 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.95 -8.52 -0.61 4.42e-14 Chronic sinus infection; TGCT cis rs75686122 0.892 rs80327507 chr8:104533054 A/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9993613 1.000 rs7697556 chr4:73515313 C/T cg15102770 chr4:73434591 ADAMTS3 0.51 4.83 0.4 3.96e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs11891 0.881 rs8079368 chr17:76989062 C/T cg25730791 chr17:76457213 DNAH17 0.4 4.61 0.38 9.67e-6 Magnesium levels; TGCT cis rs644799 1.000 rs474252 chr11:95619292 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.74 7.63 0.57 5.29e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7567389 0.599 rs6430938 chr2:128162623 A/G cg09760422 chr2:128146352 NA -0.35 -4.52 -0.38 1.4e-5 Self-rated health; TGCT cis rs2777491 0.874 rs13379756 chr15:41663896 A/C cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.1 -0.67 7.43e-18 Ulcerative colitis; TGCT cis rs9611565 0.614 rs4822053 chr22:42212936 C/A cg06634786 chr22:41940651 POLR3H -0.78 -7.33 -0.55 2.57e-11 Vitiligo; TGCT cis rs7772486 0.754 rs6570718 chr6:146088443 T/G cg23711669 chr6:146136114 FBXO30 -0.92 -10.41 -0.68 1.3e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs72781680 0.898 rs72780123 chr2:23996009 G/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs13217239 0.646 rs35691005 chr6:26972070 A/G cg15659132 chr6:26577336 NA 0.55 5.55 0.45 1.62e-7 Schizophrenia; TGCT cis rs6598955 0.671 rs12129482 chr1:26623641 C/T cg04990556 chr1:26633338 UBXN11 0.67 5.44 0.44 2.77e-7 Obesity-related traits; TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg07092213 chr7:1199455 ZFAND2A -0.51 -5.93 -0.47 2.76e-8 Longevity;Endometriosis; TGCT cis rs3820068 0.608 rs58140482 chr1:16043979 A/G cg05660106 chr1:15850417 CASP9 0.69 6.45 0.5 2.28e-9 Systolic blood pressure; TGCT cis rs16867321 0.951 rs9989767 chr2:181429886 C/T cg23363182 chr2:181467187 NA -0.39 -5.37 -0.43 3.75e-7 Obesity; TGCT cis rs4972806 0.814 rs2113560 chr2:177030986 T/C cg03152288 chr2:177042942 NA 0.61 5.21 0.42 7.53e-7 IgG glycosylation; TGCT cis rs79349575 0.749 rs58838744 chr17:46998902 A/G cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs2288073 0.930 rs7604097 chr2:24401805 G/C cg05570707 chr2:24270316 C2orf44 -0.5 -4.49 -0.37 1.58e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs6500550 0.530 rs6501178 chr16:3566362 G/A cg07396092 chr16:3662230 BTBD12 0.55 4.71 0.39 6.42e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;White blood cell count;Neutrophil count; TGCT cis rs13631 0.894 rs7856589 chr9:140003921 A/G cg14289826 chr9:140003911 NA -0.27 -6.42 -0.5 2.69e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs7017914 0.905 rs2732109 chr8:71926223 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs611744 0.934 rs682954 chr8:109210559 C/T cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs2486288 0.656 rs12908818 chr15:45571668 A/G cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.32 -0.43 4.64e-7 Glomerular filtration rate; TGCT cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg07424592 chr7:64974309 NA 1.33 7.99 0.58 7.81e-13 Diabetic kidney disease; TGCT cis rs9976767 0.608 rs9784208 chr21:43824986 A/G cg23042151 chr21:43824109 UBASH3A -0.23 -5.14 -0.42 1.02e-6 Type 1 diabetes; TGCT cis rs2072499 0.750 rs10159384 chr1:156160822 C/T cg24450063 chr1:156163899 SLC25A44 1.11 10.16 0.67 5.03e-18 Testicular germ cell tumor; TGCT cis rs68170813 0.559 rs2299422 chr7:106959832 A/T cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs1218582 0.600 rs72702224 chr1:154911689 G/A cg16680214 chr1:154839983 KCNN3 -0.38 -8.27 -0.6 1.72e-13 Prostate cancer; TGCT cis rs9467773 0.967 rs9467775 chr6:26513435 G/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs6540559 0.673 rs6540560 chr1:209982073 A/G cg21951975 chr1:209979733 IRF6 -0.6 -5.28 -0.43 5.53e-7 Cleft lip with or without cleft palate; TGCT cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg16405210 chr4:1374714 KIAA1530 -0.21 -4.62 -0.38 9.6e-6 Obesity-related traits; TGCT cis rs6866344 0.697 rs11749438 chr5:178131245 C/T cg10224037 chr5:178157518 ZNF354A 0.93 8.17 0.59 3.01e-13 Neutrophil percentage of white cells; TGCT cis rs1005277 0.603 rs1998062 chr10:38457652 G/C cg25427524 chr10:38739819 LOC399744 -0.4 -8.23 -0.59 2.17e-13 Extrinsic epigenetic age acceleration; TGCT cis rs116095464 0.558 rs62347677 chr5:227453 A/G cg22857025 chr5:266934 NA -0.32 -6.53 -0.51 1.5e-9 Breast cancer; TGCT cis rs4805272 0.626 rs12608533 chr19:29331405 C/G cg04546413 chr19:29218101 NA 0.55 4.44 0.37 2e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs2439831 0.867 rs2899082 chr15:43656043 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs16854884 0.770 rs920158 chr3:143799289 A/T cg06585982 chr3:143692056 C3orf58 0.55 4.47 0.37 1.76e-5 Economic and political preferences (feminism/equality); TGCT cis rs2191566 0.960 rs11083732 chr19:44520743 T/C cg03039196 chr19:44506973 ZNF230 0.52 4.45 0.37 1.87e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs2544527 0.586 rs2544532 chr2:15904993 C/T cg26669897 chr2:15909070 NA -0.41 -5.06 -0.41 1.5e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs9462846 0.691 rs9462853 chr6:42910666 T/C cg02353165 chr6:42928485 GNMT 0.71 5.54 0.45 1.74e-7 Blood protein levels; TGCT cis rs9467773 1.000 rs9467783 chr6:26542894 C/T cg05738196 chr6:26577821 NA 0.88 12.59 0.75 6.52e-24 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.931 rs2315558 chr4:17674558 C/A cg16339924 chr4:17578868 LAP3 0.6 5.14 0.42 1.05e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10056811 0.538 rs56174528 chr5:74400516 G/C cg19683494 chr5:74908142 NA 0.63 5.06 0.41 1.49e-6 Coronary artery disease; TGCT cis rs35146811 0.735 rs1727138 chr7:99815247 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs288326 0.561 rs74564500 chr2:183786420 C/A cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs7267979 1.000 rs6515651 chr20:25414539 T/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3749237 1.000 rs11717256 chr3:49868520 C/T cg07636037 chr3:49044803 WDR6 0.61 5.41 0.44 3.08e-7 Resting heart rate; TGCT cis rs7312933 0.703 rs12371615 chr12:42563989 C/G cg19980929 chr12:42632907 YAF2 0.47 6.47 0.5 2.03e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs12142240 0.698 rs6679898 chr1:46820589 A/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7659604 0.539 rs56159666 chr4:122782879 G/A cg06713675 chr4:122721982 EXOSC9 -0.66 -8.76 -0.62 1.24e-14 Type 2 diabetes; TGCT cis rs314370 1.000 rs10278546 chr7:100516003 G/T cg10426581 chr7:100472382 SRRT -0.9 -9.19 -0.64 1.14e-15 Resting heart rate; TGCT cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs4901869 0.966 rs425764 chr14:59334997 A/G cg02291164 chr14:59296302 NA 0.24 4.6 0.38 1.04e-5 Panic disorder; TGCT cis rs921968 0.643 rs832806 chr2:219473914 A/T cg02176678 chr2:219576539 TTLL4 0.36 5.11 0.42 1.2e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs6089829 0.851 rs6122346 chr20:61661822 C/G cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs6570726 0.791 rs407887 chr6:145843759 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.84 0.4 3.75e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg02493798 chr17:6899577 ALOX12 -0.39 -4.55 -0.38 1.24e-5 Tonsillectomy; TGCT cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg13393036 chr8:95962371 TP53INP1 -0.59 -8.08 -0.59 4.84e-13 Type 2 diabetes; TGCT cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg02187348 chr16:89574699 SPG7 0.56 5.98 0.47 2.21e-8 Multiple myeloma (IgH translocation); TGCT cis rs7216064 1.000 rs34872586 chr17:65863466 T/C cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6964587 1.000 rs12530646 chr7:91588036 A/G cg17063962 chr7:91808500 NA -0.89 -9.8 -0.66 3.93e-17 Breast cancer; TGCT cis rs28595532 0.920 rs114162429 chr4:119741078 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2180341 0.920 rs6916990 chr6:127698759 G/A cg27446573 chr6:127587934 RNF146 1.16 10.52 0.69 6.95e-19 Breast cancer; TGCT cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs6490294 0.799 rs7315642 chr12:112286796 G/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs35160687 0.901 rs12999029 chr2:86502913 G/A cg12542933 chr2:85804724 VAMP8 0.39 4.7 0.39 6.7e-6 Night sleep phenotypes; TGCT cis rs2688608 0.901 rs2664282 chr10:75620757 T/C cg19442545 chr10:75533431 FUT11 -0.32 -5.08 -0.41 1.36e-6 Inflammatory bowel disease; TGCT cis rs13242816 0.892 rs34205980 chr7:116078406 T/A cg16553024 chr7:116138462 CAV2 -0.47 -5.25 -0.43 6.52e-7 P wave duration; TGCT cis rs7937682 0.883 rs1784775 chr11:111472460 T/C cg09085632 chr11:111637200 PPP2R1B -1.07 -11.27 -0.71 1.04e-20 Primary sclerosing cholangitis; TGCT cis rs7394190 0.748 rs16930909 chr10:75561582 T/C cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs11190604 1.000 rs3750629 chr10:102275727 A/G cg23241863 chr10:102295624 HIF1AN 0.71 5.43 0.44 2.9e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg03806693 chr22:41940476 POLR3H -1.03 -11.51 -0.72 2.62e-21 Vitiligo; TGCT cis rs12497850 0.543 rs6446218 chr3:49075513 A/T cg05785598 chr3:49045655 WDR6 0.36 4.77 0.39 5e-6 Parkinson's disease; TGCT cis rs5769707 0.935 rs5770594 chr22:50018497 G/A cg05373962 chr22:49881684 NA -0.3 -6.29 -0.49 5.08e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs17401966 0.931 rs4846205 chr1:10310214 A/T cg19773385 chr1:10388646 KIF1B -0.21 -4.6 -0.38 1.02e-5 Hepatocellular carcinoma; TGCT cis rs4727027 0.704 rs12704070 chr7:148902789 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.51 0.38 1.49e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12497850 1.000 rs4858831 chr3:48735558 C/T cg16497277 chr3:49208875 KLHDC8B -0.5 -4.82 -0.4 4.06e-6 Parkinson's disease; TGCT cis rs6912958 0.559 rs451829 chr6:88041919 A/G cg04972856 chr6:88032051 C6orf162;GJB7 0.41 4.81 0.4 4.22e-6 Monocyte percentage of white cells; TGCT cis rs7267979 1.000 rs2482940 chr20:25349830 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10089 0.953 rs1985268 chr5:127375931 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs6570726 0.846 rs6570698 chr6:145918635 C/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.5 -0.37 1.53e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9297145 0.565 rs4729516 chr7:98745679 G/A cg05967295 chr7:98741636 SMURF1 -0.68 -8.66 -0.61 2.13e-14 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg17178900 chr1:205818956 PM20D1 0.55 6.81 0.52 3.67e-10 Menarche (age at onset); TGCT cis rs514406 0.861 rs2065477 chr1:53250213 C/T cg08859206 chr1:53392774 SCP2 -0.39 -5.76 -0.46 6.38e-8 Monocyte count; TGCT cis rs2153535 0.504 rs4493781 chr6:8473941 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.7 0.46 8.28e-8 Motion sickness; TGCT cis rs6733011 0.508 rs925887 chr2:99514671 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.56 5.55 0.45 1.64e-7 Bipolar disorder; TGCT cis rs12701220 0.901 rs12701708 chr7:1090333 C/T cg07217954 chr7:1067459 C7orf50 -0.48 -4.69 -0.39 7.22e-6 Bronchopulmonary dysplasia; TGCT cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.62 6.62 0.51 9.68e-10 Height; TGCT cis rs28362721 0.585 rs17159702 chr7:30959002 A/G cg04863452 chr7:30722163 CRHR2 0.5 4.52 0.38 1.41e-5 Total body bone mineral density; TGCT cis rs295140 0.903 rs10931898 chr2:201171191 C/G cg04283868 chr2:201171347 SPATS2L 0.6 5.95 0.47 2.55e-8 QT interval; TGCT cis rs6121246 0.542 rs6059761 chr20:30110522 G/C cg21427119 chr20:30132790 HM13 -0.39 -5.6 -0.45 1.32e-7 Mean corpuscular hemoglobin; TGCT cis rs7681440 0.904 rs10004413 chr4:90769479 T/C cg01966878 chr4:90757139 SNCA -0.25 -4.53 -0.38 1.39e-5 Dementia with Lewy bodies; TGCT cis rs7845219 0.544 rs6987400 chr8:95921295 T/C cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs4383453 0.539 rs4677888 chr3:123101253 G/T cg04890266 chr3:123102914 ADCY5 -0.49 -8.13 -0.59 3.67e-13 Gestational age at birth (maternal effect); TGCT cis rs7666738 0.830 rs7696715 chr4:98938486 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.851 rs7276103 chr21:46666078 G/A cg06618935 chr21:46677482 NA -0.34 -5.25 -0.43 6.33e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs447921 0.861 rs452868 chr17:74421483 C/A cg09812376 chr17:74270190 QRICH2 0.46 4.6 0.38 1.01e-5 Mitochondrial DNA levels; TGCT cis rs5167 0.534 rs56803710 chr19:45481884 C/T cg13119609 chr19:45449297 APOC2 0.23 4.65 0.39 8.26e-6 Blood protein levels; TGCT cis rs17030434 0.834 rs6535958 chr4:154760834 C/G cg14289246 chr4:154710475 SFRP2 0.88 7.58 0.56 6.86e-12 Electrocardiographic conduction measures; TGCT cis rs3020333 0.653 rs851985 chr6:152020390 G/T cg22157087 chr6:152012887 ESR1 -0.23 -5.52 -0.44 1.93e-7 Total body bone mineral density; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg25703541 chr22:24373054 LOC391322 -0.82 -8.61 -0.61 2.77e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg17054783 chr10:134559939 INPP5A 0.23 4.67 0.39 7.74e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3764563 0.660 rs8107923 chr19:15737899 A/T cg20725493 chr19:15740067 CYP4F8 -0.43 -4.67 -0.39 7.75e-6 Inflammatory biomarkers; TGCT cis rs2439831 0.681 rs1549523 chr15:43624189 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.9 6.73 0.52 5.55e-10 Lung cancer in ever smokers; TGCT cis rs7769051 1.000 rs7765224 chr6:133101624 T/C cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs7698623 0.850 rs1477604 chr4:88771060 C/T cg02735620 chr4:88950514 PKD2 -0.43 -4.66 -0.39 8.05e-6 Cardiovascular disease risk factors; TGCT cis rs2346177 0.844 rs12991646 chr2:46643831 A/G cg26688816 chr2:46740690 ATP6V1E2 -0.42 -4.48 -0.37 1.66e-5 HDL cholesterol; TGCT cis rs854765 0.583 rs9908832 chr17:17871068 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.55 0.56 8.23e-12 Total body bone mineral density; TGCT cis rs736408 1.000 rs4687552 chr3:52838402 T/C cg10802521 chr3:52805072 NEK4 -0.67 -7.27 -0.55 3.55e-11 Bipolar disorder; TGCT cis rs7617773 0.851 rs13068288 chr3:48331751 A/T cg11946769 chr3:48343235 NME6 0.74 6.16 0.48 9.49e-9 Coronary artery disease; TGCT cis rs11722228 0.964 rs10939614 chr4:9926613 T/C cg00071950 chr4:10020882 SLC2A9 -0.47 -4.81 -0.4 4.22e-6 Gout;Urate levels;Serum uric acid levels; TGCT cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs7677751 0.806 rs4864859 chr4:55090015 A/G cg17187183 chr4:55093834 PDGFRA 0.53 6.87 0.52 2.83e-10 Corneal astigmatism; TGCT cis rs7647973 0.925 rs4384984 chr3:49289878 T/G cg07690219 chr3:49449608 TCTA;RHOA -0.55 -4.48 -0.37 1.68e-5 Menarche (age at onset); TGCT trans rs2727020 0.894 rs10839265 chr11:49369733 C/T cg03929089 chr4:120376271 NA -0.67 -6.99 -0.53 1.52e-10 Coronary artery disease; TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg16049864 chr8:95962084 TP53INP1 0.7 9.92 0.67 1.94e-17 Type 2 diabetes; TGCT cis rs12477438 0.798 rs1993230 chr2:99686079 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT trans rs7615952 0.673 rs3811677 chr3:125648080 G/A cg07211511 chr3:129823064 LOC729375 -0.47 -7.55 -0.56 8.34e-12 Blood pressure (smoking interaction); TGCT cis rs12368653 0.591 rs1038914 chr12:58011066 G/A cg00700412 chr12:58011837 NA -0.23 -4.62 -0.38 9.42e-6 Multiple sclerosis; TGCT cis rs6484504 0.576 rs158146 chr11:31210433 G/A cg26647111 chr11:31128758 NA -0.34 -4.62 -0.38 9.36e-6 Red blood cell count; TGCT cis rs2067615 0.579 rs4964492 chr12:107222774 C/T cg15890332 chr12:107067104 RFX4 0.28 5.64 0.45 1.1e-7 Heart rate; TGCT cis rs7216064 0.953 rs2086744 chr17:65849275 C/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7666738 0.830 rs60994860 chr4:99046753 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6988636 0.901 rs62521825 chr8:124185786 C/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs1372520 0.564 rs356186 chr4:90705364 A/G cg14346243 chr4:90757452 SNCA -0.59 -4.84 -0.4 3.76e-6 Neuroticism; TGCT trans rs751984 0.706 rs7947046 chr11:61259751 C/T cg03305746 chr2:106927199 NA 0.54 6.62 0.51 9.83e-10 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT trans rs561341 1.000 rs8070262 chr17:30262467 A/G cg20587970 chr11:113659929 NA -0.83 -7.97 -0.58 8.86e-13 Hip circumference adjusted for BMI; TGCT cis rs11190604 1.000 rs2298074 chr10:102247526 G/C cg23241863 chr10:102295624 HIF1AN 0.6 4.54 0.38 1.3e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2708977 0.637 rs654224 chr2:97080123 A/C cg01950434 chr2:97203154 ARID5A -0.55 -4.72 -0.39 6.22e-6 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7727544 0.606 rs2631360 chr5:131707429 A/G cg14196790 chr5:131705035 SLC22A5 0.38 5.37 0.43 3.8e-7 Blood metabolite levels; TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg14159672 chr1:205819179 PM20D1 -0.57 -7.15 -0.54 6.7e-11 Monocyte percentage of white cells; TGCT cis rs2115630 1.000 rs58581703 chr15:85276935 C/T cg17173187 chr15:85201210 NMB -0.39 -4.85 -0.4 3.67e-6 P wave terminal force; TGCT cis rs1799949 0.536 rs4793227 chr17:41412250 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.42 4.44 0.37 1.93e-5 Menopause (age at onset); TGCT cis rs28735056 1.000 rs28735056 chr18:77622879 A/G cg20368463 chr18:77673604 PQLC1 -0.45 -5.66 -0.45 9.83e-8 Schizophrenia; TGCT cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs11785400 0.753 rs9694286 chr8:143737157 G/T cg10596483 chr8:143751796 JRK 0.57 5.64 0.45 1.11e-7 Schizophrenia; TGCT cis rs9811920 0.514 rs1287283 chr3:99515750 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.81 0.52 3.75e-10 Axial length; TGCT cis rs9611565 0.649 rs2413659 chr22:42164862 A/G cg03806693 chr22:41940476 POLR3H 0.9 8.7 0.62 1.7e-14 Vitiligo; TGCT cis rs4805272 0.626 rs12610050 chr19:29331324 A/T cg04546413 chr19:29218101 NA 0.55 4.44 0.37 2e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs1205863 1.000 rs864245 chr6:11943505 A/G cg07106625 chr6:11870215 NA 0.49 4.94 0.41 2.46e-6 Disc degeneration (lumbar); TGCT cis rs7394190 0.630 rs78845904 chr10:75517249 C/A cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.48e-6 Incident atrial fibrillation; TGCT cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT cis rs9322193 0.923 rs9479494 chr6:150060244 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs7909074 0.766 rs5000415 chr10:45383674 C/T cg05187965 chr10:45406764 TMEM72 -0.27 -5.76 -0.46 6.14e-8 Mean corpuscular volume; TGCT cis rs763121 0.853 rs6519119 chr22:38989007 C/G cg06022373 chr22:39101656 GTPBP1 0.78 7.44 0.56 1.48e-11 Menopause (age at onset); TGCT cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.875 rs2777483 chr6:146329235 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.55 0.65 1.57e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6426558 0.537 rs2813950 chr1:227426072 A/G cg10327440 chr1:227177885 CDC42BPA -0.56 -6.82 -0.52 3.54e-10 Neutrophil percentage of white cells; TGCT cis rs2637266 0.935 rs2579751 chr10:78339890 G/A cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT cis rs79349575 0.756 rs4793605 chr17:47035869 T/C cg07967210 chr17:47022446 SNF8 0.44 6.15 0.48 9.98e-9 Type 2 diabetes; TGCT cis rs288326 0.561 rs74942055 chr2:183793653 A/G cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs2066819 0.786 rs116934693 chr12:56696545 T/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs28386778 0.799 rs2665802 chr17:61995030 A/T cg01411255 chr17:61851458 DDX42;CCDC47 -0.74 -7.68 -0.57 4.18e-12 Prudent dietary pattern; TGCT cis rs1153858 1.000 rs2668747 chr15:45617216 T/C cg26924012 chr15:45694286 SPATA5L1 0.95 11.32 0.71 7.65e-21 Homoarginine levels; TGCT trans rs2832077 0.689 rs2832052 chr21:30130073 G/C cg14791747 chr16:20752902 THUMPD1 0.78 6.62 0.51 9.6e-10 Cognitive test performance; TGCT cis rs9929218 0.954 rs12599393 chr16:68829021 C/T cg03880890 chr16:69439245 NA -0.23 -4.66 -0.39 7.95e-6 Colorectal cancer; TGCT cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg06238570 chr21:40685208 BRWD1 -0.61 -6.29 -0.49 5.04e-9 Menarche (age at onset); TGCT cis rs916888 0.821 rs199507 chr17:44858855 A/G cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs12655019 0.920 rs3756586 chr5:56217196 A/G cg25190722 chr1:3801660 DFFB 0.62 7.17 0.54 5.87e-11 Breast cancer (early onset); TGCT cis rs6988636 1.000 rs16898086 chr8:124190445 A/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs17125944 0.572 rs79312783 chr14:53250296 A/T cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT trans rs11690035 1.000 rs11682833 chr2:145623920 A/G cg23726408 chr3:123498880 MYLK -0.59 -6.74 -0.52 5.29e-10 Breast cancer; TGCT cis rs1005277 0.579 rs2474563 chr10:38375938 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -7.88 -0.58 1.44e-12 Extrinsic epigenetic age acceleration; TGCT cis rs7646507 1.000 rs7646507 chr3:172476419 G/A cg10532262 chr3:172428426 NCEH1 0.97 4.9 0.4 2.89e-6 Obesity-related traits; TGCT cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg22920501 chr2:26401640 FAM59B -0.78 -6.16 -0.48 9.43e-9 Gut microbiome composition (summer); TGCT cis rs6088580 0.634 rs2225837 chr20:33005634 C/T cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs11249608 0.548 rs2132671 chr5:178457434 A/G cg01312482 chr5:178451176 ZNF879 0.49 4.79 0.39 4.73e-6 Pubertal anthropometrics; TGCT cis rs2997447 0.668 rs59978831 chr1:26446351 T/A cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs2066819 0.892 rs17118431 chr12:56667100 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs7617480 0.648 rs9882443 chr3:48749064 G/A cg06212747 chr3:49208901 KLHDC8B 0.57 4.48 0.37 1.66e-5 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs17221829 0.965 rs12278734 chr11:89461172 G/A cg02982614 chr11:89391479 FOLH1B -0.31 -5.44 -0.44 2.67e-7 Anxiety in major depressive disorder; TGCT cis rs2033711 0.870 rs7409473 chr19:58939165 A/G cg12042659 chr19:58951599 ZNF132 0.51 4.66 0.39 7.97e-6 Uric acid clearance; TGCT cis rs13168506 0.552 rs889010 chr5:135572910 C/A cg00308130 chr5:135415190 NA 0.3 4.46 0.37 1.84e-5 Stroke; TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg06896619 chr17:61851486 DDX42;CCDC47 0.52 5.28 0.43 5.68e-7 Prudent dietary pattern; TGCT cis rs2115536 1.000 rs7163338 chr15:80198408 C/G cg00225070 chr15:80189496 MTHFS 0.59 5.26 0.43 6.05e-7 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6061231 0.834 rs2427307 chr20:60966686 G/A cg24112000 chr20:60950667 NA -0.35 -4.86 -0.4 3.49e-6 Colorectal cancer; TGCT cis rs9653442 0.510 rs13415583 chr2:100764087 T/G cg22139774 chr2:100720529 AFF3 -0.36 -5.72 -0.46 7.68e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs950027 0.549 rs9920634 chr15:45596546 G/T cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.86 -0.47 3.9e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs250677 0.522 rs1432798 chr5:148383345 C/G cg18129178 chr5:148520854 ABLIM3 -0.39 -5.47 -0.44 2.39e-7 Breast cancer; TGCT trans rs208520 0.874 rs208517 chr6:66947040 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.93 -0.67 1.84e-17 Exhaled nitric oxide output; TGCT cis rs7613051 0.891 rs4343578 chr3:33052750 T/C cg19000631 chr3:33138515 GLB1;TMPPE 0.66 4.77 0.39 5.1e-6 Atopic dermatitis; TGCT cis rs4665809 1.000 rs7599132 chr2:26279810 A/T cg22920501 chr2:26401640 FAM59B 0.71 6.41 0.5 2.74e-9 Gut microbiome composition (summer); TGCT cis rs208520 0.526 rs9354370 chr6:66808209 C/T cg07460842 chr6:66804631 NA 1.06 15.79 0.82 1.8e-31 Exhaled nitric oxide output; TGCT cis rs36051895 0.632 rs10974979 chr9:5131731 C/A cg02405213 chr9:5042618 JAK2 -0.71 -9.55 -0.65 1.57e-16 Pediatric autoimmune diseases; TGCT cis rs17681684 0.565 rs12150182 chr17:9764757 C/T cg15743799 chr17:9805578 RCVRN -0.27 -5.89 -0.47 3.45e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs17401966 0.800 rs12122029 chr1:10339822 G/A cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg20637647 chr7:64974828 NA -0.92 -5.09 -0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs4665809 0.590 rs13019536 chr2:26526978 C/A cg22920501 chr2:26401640 FAM59B -0.79 -5.42 -0.44 2.94e-7 Gut microbiome composition (summer); TGCT cis rs7547997 0.685 rs11264965 chr1:158352400 T/G cg07950803 chr1:158223934 CD1A 0.32 4.78 0.39 4.95e-6 QRS duration; TGCT cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg17554472 chr22:41940697 POLR3H -0.46 -4.71 -0.39 6.63e-6 Vitiligo; TGCT cis rs736408 0.812 rs9324 chr3:52825585 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.53 4.86 0.4 3.5e-6 Bipolar disorder; TGCT cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg04025307 chr7:1156635 C7orf50 0.22 5.3 0.43 5.19e-7 Longevity;Endometriosis; TGCT cis rs910187 0.571 rs6512428 chr20:45807822 T/C cg27589058 chr20:45804311 EYA2 -0.4 -9.0 -0.63 3.33e-15 Migraine; TGCT cis rs9814567 0.964 rs9815983 chr3:134222507 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs208520 0.874 rs208491 chr6:66928459 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.05 -0.67 9.41e-18 Exhaled nitric oxide output; TGCT cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg24531977 chr5:56204891 C5orf35 0.97 9.1 0.63 1.86e-15 Initial pursuit acceleration; TGCT cis rs3733585 0.638 rs6414766 chr4:9956474 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8067545 1.000 rs7211535 chr17:19922364 A/G cg13482628 chr17:19912719 NA 0.56 4.82 0.4 4.18e-6 Schizophrenia; TGCT cis rs4321325 0.733 rs4510165 chr2:127936284 C/T cg09760422 chr2:128146352 NA 0.41 4.5 0.37 1.56e-5 Protein C levels; TGCT cis rs58688157 0.960 rs12422022 chr11:613192 A/G cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs10510102 0.872 rs11200267 chr10:123689366 A/T cg23691251 chr10:123688108 ATE1 -0.56 -4.51 -0.38 1.46e-5 Breast cancer; TGCT cis rs4889855 0.614 rs7208670 chr17:78494220 T/G cg16591659 chr17:78472290 NA -0.35 -5.56 -0.45 1.58e-7 Fractional excretion of uric acid; TGCT cis rs769267 0.896 rs11882123 chr19:19386339 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs9291683 0.561 rs3733584 chr4:10036506 T/C cg00071950 chr4:10020882 SLC2A9 0.68 8.84 0.62 7.71e-15 Bone mineral density; TGCT trans rs916888 0.773 rs199447 chr17:44812188 C/T cg10053473 chr17:62856997 LRRC37A3 -0.46 -6.76 -0.52 4.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9322193 0.923 rs4421206 chr6:150004027 A/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2535633 0.631 rs2710346 chr3:52974152 C/T cg10802521 chr3:52805072 NEK4 0.54 5.71 0.46 7.74e-8 Body mass index; TGCT cis rs7744392 0.557 rs9658083 chr6:35337291 G/C cg06087101 chr6:35551932 FKBP5 0.61 4.56 0.38 1.21e-5 Cataracts in type 2 diabetes; TGCT cis rs9914988 0.943 rs4795467 chr17:27180784 C/T cg20469991 chr17:27169893 C17orf63 -0.72 -4.72 -0.39 6.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs3093024 0.839 rs968334 chr6:167526096 T/C cg07741184 chr6:167504864 NA -0.24 -4.69 -0.39 7.01e-6 Rheumatoid arthritis; TGCT cis rs8016982 0.674 rs1957549 chr14:81706179 G/A cg01989461 chr14:81687754 GTF2A1 0.84 8.66 0.61 2.12e-14 Schizophrenia; TGCT cis rs1055129 0.655 rs7223416 chr17:73836162 C/G cg10935138 chr17:73851978 WBP2 0.53 4.58 0.38 1.13e-5 White matter hyperintensity burden; TGCT cis rs7246657 0.765 rs4803262 chr19:38066760 G/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs765787 0.530 rs1706834 chr15:45517854 G/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.37 -0.43 3.78e-7 Uric acid levels; TGCT cis rs1200821 0.529 rs4934856 chr10:37807847 T/C cg25427524 chr10:38739819 LOC399744 0.3 5.29 0.43 5.23e-7 Hemostatic factors and hematological phenotypes; TGCT cis rs9611565 0.921 rs2235846 chr22:41741042 G/C cg13695892 chr22:41940480 POLR3H -0.72 -7.37 -0.55 2.15e-11 Vitiligo; TGCT cis rs12451471 0.620 rs11150846 chr17:78098520 C/T cg06718696 chr17:78121285 EIF4A3 0.74 6.04 0.48 1.69e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs3087591 0.639 rs734403 chr17:29723346 T/C cg24425628 chr17:29625626 OMG;NF1 0.4 5.85 0.47 4.05e-8 Hip circumference; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg03885119 chr10:117885028 GFRA1 -0.86 -6.85 -0.52 3.06e-10 Follicular lymphoma; TGCT cis rs7267979 0.844 rs6132824 chr20:25238173 T/C cg03522245 chr20:25566470 NINL 0.57 5.67 0.45 9.54e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2806561 0.704 rs674386 chr1:23521835 G/A cg12483005 chr1:23474871 LUZP1 0.42 5.41 0.44 3.15e-7 Height; TGCT cis rs739496 0.947 rs7973120 chr12:111856738 T/A cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs35146811 0.586 rs12666107 chr7:99778019 G/C cg04778012 chr7:99775508 STAG3;GPC2 0.34 4.66 0.39 8.03e-6 Coronary artery disease; TGCT cis rs6815814 0.898 rs5743592 chr4:38803063 A/G cg02016764 chr4:38805732 TLR1 -0.37 -6.35 -0.5 3.67e-9 Breast cancer; TGCT cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg20607798 chr8:58055168 NA 0.59 4.94 0.41 2.46e-6 Developmental language disorder (linguistic errors); TGCT cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs921968 0.643 rs537520 chr2:219381852 A/G cg02176678 chr2:219576539 TTLL4 0.43 6.35 0.5 3.63e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs80282103 0.618 rs2387299 chr10:1163427 A/G cg08668510 chr10:1095578 IDI1 1.06 5.02 0.41 1.79e-6 Glomerular filtration rate (creatinine); TGCT cis rs11190604 1.000 rs3793706 chr10:102269085 A/C cg16342193 chr10:102329863 NA 0.39 5.01 0.41 1.83e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs667920 0.573 rs9682783 chr3:136539689 T/C cg15507776 chr3:136538369 TMEM22 0.67 6.5 0.5 1.81e-9 Coronary artery disease; TGCT cis rs5769765 0.624 rs138843 chr22:50183162 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.94 -8.34 -0.6 1.21e-13 Schizophrenia; TGCT cis rs11190604 0.767 rs7090150 chr10:102173446 G/T cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg22168489 chr12:122356033 WDR66 0.23 5.55 0.45 1.63e-7 Mean corpuscular volume; TGCT cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg03264133 chr6:25882463 NA -0.61 -5.68 -0.45 8.98e-8 Intelligence (multi-trait analysis); TGCT cis rs9910055 0.529 rs228764 chr17:42185469 A/G cg13607699 chr17:42295918 UBTF -0.62 -4.97 -0.41 2.18e-6 Total body bone mineral density; TGCT cis rs9921338 0.961 rs72773829 chr16:11412623 G/A cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4629710 0.592 rs9492865 chr6:131534403 T/A cg12606694 chr6:131520996 AKAP7 0.39 4.62 0.38 9.58e-6 Multiple myeloma (IgH translocation); TGCT cis rs6430585 0.702 rs2304601 chr2:136528034 C/A cg07169764 chr2:136633963 MCM6 1.2 11.43 0.72 4.14e-21 Corneal structure; TGCT cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg07061783 chr6:25882402 NA -0.58 -5.6 -0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs9383153 1.000 rs2237223 chr6:16329741 G/A cg23850913 chr6:15505452 JARID2 0.92 4.86 0.4 3.42e-6 Gambling; TGCT cis rs6750047 0.719 rs4670232 chr2:38272033 C/G cg07380506 chr2:38303506 CYP1B1 0.56 5.05 0.41 1.51e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs1218582 0.772 rs906593 chr1:154885255 G/A cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs3020736 0.500 rs2839708 chr22:42500745 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs7615952 0.932 rs9841157 chr3:125635655 C/A cg07211511 chr3:129823064 LOC729375 -0.45 -6.72 -0.52 5.83e-10 Blood pressure (smoking interaction); TGCT cis rs4851254 0.920 rs13011874 chr2:100752497 C/T cg23118464 chr2:100721844 AFF3 0.71 5.28 0.43 5.6e-7 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.565 rs2150414 chr21:40614988 A/G cg11644478 chr21:40555479 PSMG1 -0.53 -4.86 -0.4 3.53e-6 Menarche (age at onset); TGCT cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.43 6.12 0.48 1.13e-8 Alzheimer's disease; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg25703541 chr22:24373054 LOC391322 -0.82 -8.62 -0.61 2.61e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs597539 0.652 rs622082 chr11:68703959 A/G cg04772025 chr11:68637568 NA 0.62 6.89 0.53 2.52e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7226408 0.857 rs72885275 chr18:34439624 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs8072100 0.905 rs8078686 chr17:45735706 T/C cg08085267 chr17:45401833 C17orf57 0.43 4.74 0.39 5.86e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs10504229 0.679 rs12375285 chr8:58040084 G/A cg20607798 chr8:58055168 NA 0.45 4.68 0.39 7.52e-6 Developmental language disorder (linguistic errors); TGCT cis rs3741404 0.931 rs594942 chr11:64006292 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 -0.87 -9.49 -0.65 2.14e-16 Platelet count; TGCT cis rs7681440 0.728 rs974711 chr4:90737327 G/A cg26578617 chr4:90757533 SNCA -0.45 -4.58 -0.38 1.1e-5 Dementia with Lewy bodies; TGCT cis rs514406 0.621 rs928452 chr1:53195926 G/C cg24675658 chr1:53192096 ZYG11B 0.84 10.45 0.68 1.03e-18 Monocyte count; TGCT cis rs7255045 0.742 rs10420014 chr19:12960947 G/T cg23899408 chr19:12877188 HOOK2 -0.56 -4.44 -0.37 1.96e-5 Mean corpuscular volume; TGCT cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs2346177 0.875 rs2166745 chr2:46646879 C/G cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.75 -0.39 5.45e-6 HDL cholesterol; TGCT cis rs9660180 0.620 rs3817856 chr1:1663831 C/T cg27541892 chr1:1571801 CDK11B -0.4 -5.34 -0.43 4.24e-7 Body mass index; TGCT cis rs35146811 0.735 rs6948729 chr7:99787372 A/G cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs1005277 0.579 rs2474588 chr10:38420870 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.03 -0.58 6.56e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9560113 1.000 rs60374273 chr13:112179206 A/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs5750830 0.621 rs5757665 chr22:39821641 A/G cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs10927875 0.632 rs6699394 chr1:16145143 C/A cg21385522 chr1:16154831 NA -1.0 -17.85 -0.85 4.62e-36 Dilated cardiomyopathy; TGCT cis rs885389 1.000 rs885389 chr12:131621762 C/T cg07124762 chr12:131619285 GPR133 0.3 5.94 0.47 2.74e-8 RR interval (heart rate); TGCT cis rs11122272 0.705 rs2572260 chr1:231486189 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.88 -0.53 2.66e-10 Hemoglobin concentration; TGCT cis rs3733585 0.683 rs13112015 chr4:9933796 C/T cg00071950 chr4:10020882 SLC2A9 -0.61 -7.25 -0.55 3.96e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2455799 0.613 rs4685269 chr3:15942354 A/G cg16303742 chr3:15540471 COLQ -0.24 -4.53 -0.38 1.36e-5 Mean platelet volume; TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs35306767 0.714 rs7075188 chr10:1088746 G/T cg26597838 chr10:835615 NA -0.46 -5.12 -0.42 1.16e-6 Eosinophil percentage of granulocytes; TGCT cis rs7215564 0.818 rs4889776 chr17:78592385 C/T cg23263226 chr17:78226839 SLC26A11 0.45 4.56 0.38 1.23e-5 Myopia (pathological); TGCT cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs9611565 0.504 rs5758452 chr22:42144927 G/A cg03806693 chr22:41940476 POLR3H 0.9 8.76 0.62 1.2e-14 Vitiligo; TGCT cis rs17443541 0.507 rs1450568 chr2:200446732 A/T cg00055341 chr2:200446845 NA -0.38 -4.6 -0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs66561647 0.661 rs7387614 chr8:128929353 C/T cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.55 0.38 1.24e-5 Hemoglobin concentration; TGCT cis rs12220238 0.722 rs11001087 chr10:76384602 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 4.89 0.4 3.02e-6 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9534288 0.797 rs1134071 chr13:46562935 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs35883536 1.000 rs964906 chr1:101087479 G/A cg06223162 chr1:101003688 GPR88 0.31 4.89 0.4 3.07e-6 Monocyte count; TGCT cis rs11578119 0.933 rs12130086 chr1:170483041 T/A cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs2551802 0.615 rs17395735 chr2:177067780 C/T cg13092806 chr2:177043255 NA 0.55 4.45 0.37 1.92e-5 Motion sickness; TGCT cis rs9467773 1.000 rs9467782 chr6:26542773 G/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs8031584 0.723 rs711224 chr15:31127921 G/C cg08109568 chr15:31115862 NA 0.39 5.19 0.42 8.33e-7 Huntington's disease progression; TGCT cis rs9560113 0.960 rs950891 chr13:112173992 G/A cg14154082 chr13:112174009 NA -0.36 -5.06 -0.41 1.46e-6 Menarche (age at onset); TGCT cis rs9435341 0.965 rs56111229 chr1:107566689 T/A cg09367891 chr1:107599246 PRMT6 0.62 5.4 0.44 3.22e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs1023500 0.596 rs5758562 chr22:42448238 C/G cg05082376 chr22:42548792 NA -0.22 -5.29 -0.43 5.32e-7 Schizophrenia; TGCT cis rs7605378 1.000 rs2577852 chr2:200687248 C/T cg17644776 chr2:200775616 C2orf69 0.29 5.51 0.44 1.94e-7 Osteoporosis; TGCT cis rs8102137 0.588 rs7257694 chr19:30314666 C/T cg09247459 chr19:30364939 NA 0.3 4.61 0.38 9.9e-6 Bladder cancer; TGCT cis rs2120019 1.000 rs67544533 chr15:75361539 A/G cg17294928 chr15:75287854 SCAMP5 -0.83 -6.32 -0.49 4.37e-9 Blood trace element (Zn levels); TGCT cis rs7178572 0.539 rs16968809 chr15:77672118 C/T cg22256960 chr15:77711686 NA 0.84 8.15 0.59 3.39e-13 Type 2 diabetes; TGCT cis rs7781977 0.735 rs716719 chr7:50325717 A/C cg01139861 chr7:50343298 IKZF1 -0.44 -4.64 -0.38 8.75e-6 IgG glycosylation; TGCT cis rs826838 0.510 rs10876149 chr12:39228083 C/G cg26384229 chr12:38710491 ALG10B -0.59 -4.8 -0.4 4.41e-6 Heart rate; TGCT cis rs13064411 0.660 rs11916690 chr3:113012343 A/C cg18753928 chr3:113234510 CCDC52 -0.69 -4.93 -0.4 2.58e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs71636778 0.509 rs12739698 chr1:27230033 G/A cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs73001065 0.901 rs73004959 chr19:19711139 C/T cg03709012 chr19:19516395 GATAD2A 1.03 5.08 0.41 1.36e-6 LDL cholesterol; TGCT cis rs514406 0.505 rs374662 chr1:53164549 C/A cg01802117 chr1:53393560 SCP2 -0.42 -4.84 -0.4 3.86e-6 Monocyte count; TGCT trans rs7726839 0.794 rs6883536 chr5:599274 G/A cg11887960 chr12:57824829 NA 0.97 7.56 0.56 7.58e-12 Obesity-related traits; TGCT cis rs59197085 0.534 rs2307038 chr7:128449356 A/C cg00260937 chr7:128520193 KCP 0.47 4.9 0.4 2.92e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs2180341 0.889 rs2000909 chr6:127711173 G/A cg24812749 chr6:127587940 RNF146 0.79 6.58 0.51 1.21e-9 Breast cancer; TGCT cis rs875971 0.830 rs427973 chr7:65526648 C/A cg18876405 chr7:65276391 NA 0.33 4.95 0.41 2.39e-6 Aortic root size; TGCT cis rs3849570 0.533 rs4440144 chr3:81988359 A/G cg07356753 chr3:81810745 GBE1 -0.54 -4.5 -0.37 1.52e-5 Waist circumference;Body mass index; TGCT cis rs6089584 0.706 rs6089625 chr20:60620622 T/C cg13665807 chr20:60559372 TAF4 -0.46 -4.9 -0.4 2.87e-6 Body mass index; TGCT cis rs7542091 0.506 rs992976 chr1:210066658 A/T cg22029157 chr1:209979665 IRF6 -0.52 -4.89 -0.4 3.03e-6 Monobrow; TGCT cis rs61990749 0.544 rs8003979 chr14:78211290 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs28735056 0.933 rs499260 chr18:77589689 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.53 -0.44 1.84e-7 Schizophrenia; TGCT cis rs1712517 0.525 rs2271751 chr10:105175131 A/G cg04362960 chr10:104952993 NT5C2 -0.56 -4.67 -0.39 7.69e-6 Migraine; TGCT cis rs921968 0.541 rs2241527 chr2:219537224 A/G cg02176678 chr2:219576539 TTLL4 0.51 7.55 0.56 8.06e-12 Mean corpuscular hemoglobin concentration; TGCT cis rs1801251 1.000 rs4517962 chr2:233578337 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.3e-9 Coronary artery disease; TGCT cis rs950169 0.580 rs11633762 chr15:85187152 T/C cg17173187 chr15:85201210 NMB 0.61 6.94 0.53 1.92e-10 Schizophrenia; TGCT cis rs10206020 0.921 rs6605278 chr2:1547230 C/T cg01028140 chr2:1542097 TPO -0.32 -4.65 -0.39 8.2e-6 IgG glycosylation; TGCT cis rs651907 0.557 rs11914318 chr3:101453858 C/T cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.78 -0.52 4.35e-10 Colorectal cancer; TGCT cis rs13256369 0.951 rs10503394 chr8:8565775 A/G cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.45e-5 Obesity-related traits; TGCT cis rs734999 0.869 rs61054170 chr1:2498052 C/T cg17806162 chr1:2472133 NA -0.26 -4.46 -0.37 1.78e-5 Ulcerative colitis; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg15242686 chr22:24348715 GSTTP1 0.45 6.4 0.5 2.86e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.57 4.85 0.4 3.59e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.850 rs694985 chr15:43813387 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.94 7.52 0.56 9.73e-12 Lung cancer in ever smokers; TGCT cis rs4455778 0.580 rs4607559 chr7:49121902 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs28785552 0.931 rs10424385 chr19:53239133 C/G cg10871876 chr19:53194124 ZNF83 0.62 8.85 0.62 7.42e-15 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs11148252 0.557 rs9536223 chr13:53233194 A/T cg00495681 chr13:53174319 NA 0.65 6.56 0.51 1.32e-9 Lewy body disease; TGCT cis rs8016982 0.617 rs2241621 chr14:81737076 G/T cg01989461 chr14:81687754 GTF2A1 -0.65 -6.49 -0.5 1.85e-9 Schizophrenia; TGCT cis rs7255045 0.742 rs6511840 chr19:12954720 C/T cg23899408 chr19:12877188 HOOK2 -0.59 -4.86 -0.4 3.44e-6 Mean corpuscular volume; TGCT cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs950169 0.922 rs12915832 chr15:85111457 C/T cg17173187 chr15:85201210 NMB 0.48 5.02 0.41 1.75e-6 Schizophrenia; TGCT cis rs2439831 0.681 rs1549525 chr15:43627855 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.9 6.73 0.52 5.55e-10 Lung cancer in ever smokers; TGCT cis rs3820068 0.705 rs4646072 chr1:15827711 G/A cg05660106 chr1:15850417 CASP9 1.18 13.63 0.77 2.04e-26 Systolic blood pressure; TGCT cis rs7552404 0.731 rs12090849 chr1:76400261 A/G cg10523679 chr1:76189770 ACADM 0.8 6.99 0.53 1.52e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2361710 1.000 rs2361710 chr17:78111877 C/T cg09238746 chr17:78121135 EIF4A3 0.69 6.43 0.5 2.51e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs7666738 1.000 rs880471 chr4:98922541 C/T cg17366294 chr4:99064904 C4orf37 0.72 6.58 0.51 1.17e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.743 rs9403742 chr6:146060193 A/C cg05347473 chr6:146136440 FBXO30 0.48 4.51 0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1670533 1.000 rs62294756 chr4:1097676 G/A cg20518497 chr4:1046821 NA 0.27 4.46 0.37 1.84e-5 Recombination rate (females); TGCT cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs7017914 0.967 rs12675271 chr8:71602009 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.51 -4.68 -0.39 7.43e-6 Bone mineral density; TGCT cis rs7267979 1.000 rs6115153 chr20:25325567 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2657888 0.899 rs7300877 chr12:56933233 C/A cg23932658 chr12:57637574 STAC3 0.48 4.56 0.38 1.19e-5 Adiponectin levels; TGCT cis rs7258465 1.000 rs10427083 chr19:18550276 C/A cg06462663 chr19:18546047 ISYNA1 0.2 4.54 0.38 1.33e-5 Breast cancer; TGCT cis rs17376456 0.597 rs7733142 chr5:93322795 C/A cg25358565 chr5:93447407 FAM172A -0.64 -6.0 -0.47 2e-8 Diabetic retinopathy; TGCT cis rs7917772 0.539 rs12572775 chr10:104285594 A/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.56 -5.31 -0.43 4.92e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2153535 0.580 rs7341201 chr6:8470270 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9381040 0.655 rs6903444 chr6:41014220 C/T cg03526776 chr6:41159608 TREML2 -0.27 -5.34 -0.43 4.33e-7 Alzheimer's disease (late onset); TGCT cis rs2760061 0.819 rs708111 chr1:228191365 G/A cg18477163 chr1:228402036 OBSCN 0.34 7.16 0.54 6.26e-11 Diastolic blood pressure; TGCT cis rs9467711 0.606 rs2235251 chr6:26431982 C/T cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7208859 0.623 rs9914242 chr17:29216245 G/T cg14008862 chr17:28927542 LRRC37B2 0.69 4.46 0.37 1.83e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2159324 1.000 rs2109065 chr19:45695610 T/A cg24080119 chr19:45644694 NA 0.3 4.78 0.39 4.78e-6 Quantitative traits; TGCT cis rs2777491 0.574 rs28700583 chr15:41714072 C/T cg18705301 chr15:41695430 NDUFAF1 -0.94 -17.34 -0.84 6.15e-35 Ulcerative colitis; TGCT cis rs7614311 0.636 rs73130576 chr3:63890875 T/C cg22134162 chr3:63841271 THOC7 -0.4 -5.16 -0.42 9.41e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs11122272 0.735 rs2739506 chr1:231529183 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT cis rs3820068 0.705 rs951225 chr1:15826292 G/A cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs6964587 1.000 rs7797834 chr7:91743150 C/T cg22709100 chr7:91322751 NA -0.3 -4.83 -0.4 4.02e-6 Breast cancer; TGCT cis rs13191362 1.000 rs35583420 chr6:163214327 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.94 5.88 0.47 3.54e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11676348 0.846 rs4674260 chr2:219002376 T/C cg00012203 chr2:219082015 ARPC2 -0.51 -4.86 -0.4 3.53e-6 Ulcerative colitis; TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg14159672 chr1:205819179 PM20D1 0.72 10.29 0.68 2.45e-18 Menarche (age at onset); TGCT cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg11279151 chr3:101281821 RG9MTD1 0.35 7.28 0.55 3.4e-11 Colorectal cancer; TGCT cis rs4642101 0.561 rs9831765 chr3:12805934 A/T cg05775895 chr3:12838266 CAND2 0.53 5.22 0.42 7.19e-7 QRS complex (12-leadsum); TGCT cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT trans rs7618501 0.633 rs2353579 chr3:50027774 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.38 0.64 3.95e-16 Intelligence (multi-trait analysis); TGCT cis rs694419 0.602 rs4941141 chr18:60194470 C/G cg13506219 chr18:60193840 ZCCHC2 -0.54 -4.93 -0.4 2.57e-6 Serum albumin level; TGCT cis rs9388451 0.868 rs1268083 chr6:126049040 T/C cg10911889 chr6:126070802 HEY2 -0.5 -4.84 -0.4 3.72e-6 Brugada syndrome; TGCT cis rs10089 1.000 rs4836363 chr5:127462737 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs4523957 0.583 rs2760745 chr17:2035591 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2282802 0.685 rs7717576 chr5:139623591 G/A cg01081189 chr5:139537190 NA 0.28 5.08 0.41 1.36e-6 Intelligence (multi-trait analysis); TGCT cis rs319204 0.959 rs599812 chr5:146280414 C/A cg25021259 chr5:146258546 PPP2R2B 0.36 4.6 0.38 1.02e-5 Schizophrenia; TGCT cis rs12643440 0.538 rs10939707 chr4:17146776 G/T cg22650099 chr4:17144496 NA -0.49 -5.03 -0.41 1.66e-6 Metabolite levels (Pyroglutamine); TGCT cis rs3806843 0.676 rs2245640 chr5:140029958 A/G cg19875535 chr5:140030758 IK -0.37 -6.36 -0.5 3.6e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs17601876 0.814 rs35939475 chr15:51554710 C/A cg19946085 chr15:51559439 CYP19A1 -0.32 -4.84 -0.4 3.84e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs7659604 0.518 rs17452156 chr4:122733623 T/C cg06713675 chr4:122721982 EXOSC9 -0.69 -9.69 -0.66 7.11e-17 Type 2 diabetes; TGCT cis rs1577917 0.958 rs10806337 chr6:86474249 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.48 -0.44 2.28e-7 Response to antipsychotic treatment; TGCT cis rs9898058 0.556 rs1135034 chr17:47783663 C/T cg10517230 chr17:48661425 CACNA1G 0.47 4.51 0.38 1.48e-5 Milk allergy; TGCT cis rs597539 0.652 rs627731 chr11:68698663 A/C cg06112835 chr11:68658793 MRPL21 0.45 7.64 0.57 5.19e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs79149102 0.579 rs3910748 chr15:75318652 A/G cg09165964 chr15:75287851 SCAMP5 -1.05 -5.73 -0.46 7.26e-8 Lung cancer; TGCT cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs11122272 0.735 rs2474633 chr1:231486989 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.61 -0.51 1.01e-9 Hemoglobin concentration; TGCT cis rs9467773 0.869 rs1796521 chr6:26421392 T/C cg15659132 chr6:26577336 NA -0.54 -5.67 -0.45 9.4e-8 Intelligence (multi-trait analysis); TGCT cis rs514406 0.763 rs6685599 chr1:53213172 G/A cg24675658 chr1:53192096 ZYG11B 0.71 7.96 0.58 9.48e-13 Monocyte count; TGCT cis rs9318086 0.935 rs9652080 chr13:24435426 A/C cg25267304 chr13:24462978 PCOTH;MIPEP -0.68 -6.87 -0.52 2.82e-10 Myopia (pathological); TGCT cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT trans rs1005277 0.579 rs1621040 chr10:38497232 T/C cg27523141 chr10:43048294 ZNF37B 0.71 8.17 0.59 3.03e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1697139 0.583 rs13186050 chr5:66528139 C/T cg11553311 chr5:66541588 NA 0.3 6.37 0.5 3.36e-9 Breast cancer; TGCT cis rs2836950 0.545 rs1888489 chr21:40533164 T/C cg17971929 chr21:40555470 PSMG1 -0.52 -4.64 -0.38 8.72e-6 Menarche (age at onset); TGCT cis rs72781680 0.898 rs7563564 chr2:23993404 T/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs6490294 0.748 rs2269802 chr12:112326138 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs2639990 1.000 rs1702831 chr18:72897368 C/A cg02750262 chr18:72916776 ZADH2 0.87 6.6 0.51 1.08e-9 Vascular endothelial growth factor levels; TGCT cis rs4478037 0.643 rs9875798 chr3:33120448 G/C cg19404215 chr3:33155277 CRTAP 1.28 6.37 0.5 3.33e-9 Major depressive disorder; TGCT cis rs6570726 0.791 rs9390336 chr6:145896823 A/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs763121 0.853 rs5750652 chr22:39048316 A/G cg06022373 chr22:39101656 GTPBP1 0.8 8.25 0.6 1.95e-13 Menopause (age at onset); TGCT cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.84 0.46 4.3e-8 Bipolar disorder; TGCT cis rs2836974 0.644 rs719230 chr21:40676307 C/T cg17971929 chr21:40555470 PSMG1 -0.7 -6.7 -0.52 6.41e-10 Cognitive function; TGCT cis rs3859192 0.539 rs2302774 chr17:38183090 G/T cg17467752 chr17:38218738 THRA -0.57 -5.13 -0.42 1.08e-6 White blood cell count; TGCT cis rs2235642 0.821 rs8051895 chr16:1602811 A/G cg07341220 chr16:1583899 IFT140;TMEM204 -0.29 -4.56 -0.38 1.23e-5 Coronary artery disease; TGCT cis rs13394619 0.875 rs7576826 chr2:11723021 C/T cg07314298 chr2:11723111 GREB1 -0.28 -4.85 -0.4 3.7e-6 Endometriosis; TGCT cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg07061783 chr6:25882402 NA -0.64 -6.43 -0.5 2.55e-9 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs72703083 chr5:595365 C/T cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs651907 0.535 rs13065944 chr3:101473088 G/A cg12386194 chr3:101231763 SENP7 0.48 4.63 0.38 9.23e-6 Colorectal cancer; TGCT cis rs7208859 0.673 rs1347360 chr17:28914532 T/C cg14008862 chr17:28927542 LRRC37B2 0.76 4.62 0.38 9.48e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg27535305 chr1:53392650 SCP2 -0.23 -4.63 -0.38 9.11e-6 Monocyte count; TGCT cis rs11864453 0.713 rs12708926 chr16:72126063 T/C cg14768367 chr16:72042858 DHODH 0.5 4.8 0.4 4.5e-6 Fibrinogen levels; TGCT cis rs1949733 1.000 rs1357481 chr4:8496221 A/T cg13073564 chr4:8508604 NA -0.51 -5.79 -0.46 5.44e-8 Response to antineoplastic agents; TGCT cis rs7726839 0.540 rs72705030 chr5:645562 C/T cg09021430 chr5:549028 NA -0.38 -5.23 -0.42 7.13e-7 Obesity-related traits; TGCT cis rs2276314 0.947 rs4799831 chr18:33554775 A/G cg19628046 chr18:33552617 C18orf21 0.52 4.46 0.37 1.8e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg01206211 chr2:36825736 FEZ2 0.31 4.8 0.4 4.51e-6 Height; TGCT cis rs6665290 0.935 rs6659424 chr1:227197875 A/G cg10327440 chr1:227177885 CDC42BPA -0.99 -20.11 -0.87 7.47e-41 Myeloid white cell count; TGCT cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs6754311 0.551 rs6739713 chr2:136488978 A/G cg07169764 chr2:136633963 MCM6 0.76 6.25 0.49 6.14e-9 Mosquito bite size; TGCT trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg01341218 chr17:43662625 NA 1.04 7.8 0.57 2.14e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7552404 0.731 rs17650138 chr1:76398887 C/T cg10523679 chr1:76189770 ACADM -0.93 -7.9 -0.58 1.28e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10431058 0.644 rs614759 chr11:107464386 G/T cg18204760 chr11:107461044 ELMOD1;LOC643923 0.59 5.09 0.42 1.31e-6 Common traits (Other); TGCT cis rs921968 0.612 rs496908 chr2:219357742 A/T cg02176678 chr2:219576539 TTLL4 0.45 6.57 0.51 1.23e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs2797160 0.967 rs984041 chr6:126021328 A/T cg05901451 chr6:126070800 HEY2 0.75 6.66 0.51 8e-10 Endometrial cancer; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs1395 0.778 rs4665960 chr2:27467598 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.35 0.64 4.81e-16 Blood metabolite levels; TGCT cis rs3845702 1.000 rs262279 chr2:180869145 G/A cg01881094 chr2:180872142 CWC22 0.68 6.11 0.48 1.16e-8 Schizophrenia; TGCT cis rs8017423 0.874 rs2149656 chr14:90707508 A/C cg04374321 chr14:90722782 PSMC1 0.78 7.88 0.58 1.45e-12 Mortality in heart failure; TGCT cis rs4654899 0.714 rs12401630 chr1:21495049 G/A cg01072550 chr1:21505969 NA -0.47 -6.96 -0.53 1.72e-10 Superior frontal gyrus grey matter volume; TGCT cis rs12908161 1.000 rs62021219 chr15:85256159 C/T cg17173187 chr15:85201210 NMB 0.59 6.77 0.52 4.55e-10 Schizophrenia; TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg19723775 chr5:179050963 HNRNPH1 0.53 5.32 0.43 4.71e-7 Lung cancer; TGCT cis rs4499344 0.960 rs17833075 chr19:33075134 G/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.69 -6.26 -0.49 5.75e-9 Mean platelet volume; TGCT cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg03517284 chr6:25882590 NA -0.68 -6.01 -0.47 1.94e-8 Intelligence (multi-trait analysis); TGCT cis rs4700695 0.640 rs27083 chr5:65435865 C/T cg21114390 chr5:65439923 SFRS12 -0.85 -7.61 -0.56 5.94e-12 Facial morphology (factor 19); TGCT cis rs9818758 0.607 rs67060340 chr3:48915321 C/T cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7020830 0.898 rs506981 chr9:37351348 A/T cg14294708 chr9:37120828 ZCCHC7 -1.06 -14.42 -0.79 2.83e-28 Schizophrenia; TGCT cis rs736801 0.504 rs2070721 chr5:131825842 T/G cg02551604 chr5:131831745 NA -0.76 -8.6 -0.61 2.97e-14 Breast cancer;Mosquito bite size; TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.38e-6 Prudent dietary pattern; TGCT cis rs35883536 0.609 rs12747197 chr1:101036831 A/C cg10298815 chr1:101004474 GPR88 -0.24 -4.5 -0.37 1.57e-5 Monocyte count; TGCT cis rs2836974 0.796 rs77153312 chr21:40695499 G/A cg11644478 chr21:40555479 PSMG1 0.97 9.14 0.63 1.52e-15 Cognitive function; TGCT cis rs10493773 1.000 rs10493773 chr1:86125753 C/T cg17807903 chr1:86174739 ZNHIT6 0.39 4.94 0.41 2.5e-6 Urate levels in overweight individuals; TGCT trans rs1814175 0.791 rs10839395 chr11:49846274 G/T cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.85e-13 Height; TGCT cis rs67385638 1.000 rs2855036 chr11:5272682 C/T cg12559170 chr11:5275217 HBG2 0.48 8.68 0.61 1.93e-14 Hemoglobin levels; TGCT cis rs2456568 0.571 rs1105113 chr11:93693323 G/A cg26875233 chr11:93583750 C11orf90 0.43 5.16 0.42 9.71e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1580019 0.961 rs4320456 chr7:32496003 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs17001868 0.892 rs117667045 chr22:40736961 C/T cg07138101 chr22:40742427 ADSL 0.72 4.64 0.38 8.84e-6 Mammographic density (dense area); TGCT cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg00343986 chr7:65444356 GUSB -0.22 -5.47 -0.44 2.4e-7 Calcium levels; TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs6545883 0.929 rs778140 chr2:61682976 C/T cg15711740 chr2:61764176 XPO1 -0.53 -4.79 -0.4 4.59e-6 Tuberculosis; TGCT cis rs929354 0.772 rs3802118 chr7:156986814 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs2688608 0.967 rs9971038 chr10:75661149 C/T cg04320760 chr10:75533139 FUT11 -0.31 -4.84 -0.4 3.72e-6 Inflammatory bowel disease; TGCT cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg11502198 chr6:26597334 ABT1 0.54 4.93 0.4 2.62e-6 Intelligence (multi-trait analysis); TGCT cis rs17331151 0.541 rs1139106 chr3:52871101 G/A cg15956490 chr3:53032818 SFMBT1 0.46 5.7 0.46 8.34e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7677751 0.806 rs61320297 chr4:55088175 G/A cg17187183 chr4:55093834 PDGFRA 0.54 7.13 0.54 7.45e-11 Corneal astigmatism; TGCT cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg19774624 chr17:42201019 HDAC5 -0.87 -10.63 -0.69 3.81e-19 Total body bone mineral density; TGCT cis rs17826219 0.706 rs8075357 chr17:29057197 A/C cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.46e-9 Electroencephalogram traits; TGCT cis rs7439150 0.954 rs28365897 chr4:155471982 A/C cg22130008 chr4:155548532 NA -0.45 -5.55 -0.45 1.64e-7 Fibrinogen levels; TGCT cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7172809 0.573 rs17384809 chr15:77622006 A/G cg22256960 chr15:77711686 NA 0.51 5.04 0.41 1.58e-6 Glucose homeostasis traits; TGCT cis rs7772486 0.875 rs10457793 chr6:146415403 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs6832568 chr4:98994061 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10992471 0.630 rs10992322 chr9:95159196 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.59 -0.45 1.36e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT trans rs8073060 0.586 rs225292 chr17:33926383 G/A cg19694781 chr19:47549865 TMEM160 -0.5 -10.74 -0.69 1.96e-19 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2243480 1.000 rs1796220 chr7:66062100 C/T cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs7267979 0.933 rs2387887 chr20:25427081 G/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2439831 0.681 rs11858152 chr15:43634196 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.05 9.14 0.63 1.54e-15 Lung cancer in ever smokers; TGCT cis rs10782582 0.609 rs2881785 chr1:76318096 T/C cg22875332 chr1:76189707 ACADM -0.44 -4.48 -0.37 1.7e-5 Daytime sleep phenotypes; TGCT cis rs8177179 0.967 rs4287912 chr3:133437778 A/G cg16262614 chr3:133464971 TF 0.34 4.55 0.38 1.24e-5 Iron status biomarkers (transferrin levels); TGCT cis rs4252435 0.614 rs4252417 chr7:142625258 G/A cg21621906 chr7:142494914 NA -1.06 -4.6 -0.38 1.04e-5 Cancer; TGCT cis rs295140 0.706 rs3769484 chr2:201172999 C/T cg04283868 chr2:201171347 SPATS2L 0.6 5.68 0.45 9.27e-8 QT interval; TGCT cis rs9929218 1.000 rs9937664 chr16:68784603 T/C cg01251360 chr16:68772225 CDH1 0.29 4.89 0.4 3.01e-6 Colorectal cancer; TGCT cis rs713587 0.719 rs58048722 chr2:25187825 C/T cg01884057 chr2:25150051 NA -0.38 -7.8 -0.57 2.16e-12 Body mass index in non-asthmatics; TGCT cis rs12765878 0.603 rs2475216 chr10:105660651 G/A cg11005552 chr10:105648138 OBFC1 -0.4 -6.21 -0.49 7.49e-9 Coronary artery disease; TGCT cis rs595982 0.559 rs17206714 chr19:49362001 T/A cg15549821 chr19:49342101 PLEKHA4 -0.7 -9.6 -0.65 1.17e-16 Red cell distribution width; TGCT cis rs13191362 1.000 rs13200329 chr6:163004418 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12541335 0.639 rs7003478 chr8:22201123 A/G cg07298985 chr8:22133076 PIWIL2 0.34 5.41 0.44 3.07e-7 Hypertriglyceridemia; TGCT cis rs7267979 0.586 rs6050432 chr20:25184028 T/C cg14121845 chr20:25566513 NINL 0.45 4.88 0.4 3.23e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.683 rs16921817 chr8:58107563 A/T cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs12510870 0.600 rs11733767 chr4:74427805 T/C cg05868023 chr4:75230803 EREG 0.54 4.89 0.4 3.07e-6 Iris color (b* coordinate); TGCT cis rs9611519 0.761 rs35445172 chr22:41660301 G/A cg03806693 chr22:41940476 POLR3H -0.74 -7.23 -0.54 4.46e-11 Neuroticism; TGCT cis rs7267979 0.816 rs376742 chr20:25487417 A/C cg16686733 chr20:25566563 NINL 0.51 4.91 0.4 2.82e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7681440 0.804 rs763443 chr4:90819961 T/C cg26578617 chr4:90757533 SNCA -0.43 -4.48 -0.37 1.71e-5 Dementia with Lewy bodies; TGCT cis rs826838 0.967 rs12823908 chr12:38845686 T/C cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs28595532 0.764 rs56359736 chr4:119769689 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs2797160 0.935 rs60515555 chr6:126000638 T/G cg05901451 chr6:126070800 HEY2 -0.74 -6.48 -0.5 1.96e-9 Endometrial cancer; TGCT cis rs801193 1.000 rs10252765 chr7:66228732 C/G cg18876405 chr7:65276391 NA 0.33 4.97 0.41 2.19e-6 Aortic root size; TGCT cis rs4788570 0.584 rs979790 chr16:71665985 A/T cg06353428 chr16:71660113 MARVELD3 -1.35 -9.32 -0.64 5.62e-16 Intelligence (multi-trait analysis); TGCT trans rs1005277 0.540 rs11011351 chr10:38030525 A/G cg17830980 chr10:43048298 ZNF37B -0.65 -7.34 -0.55 2.4e-11 Extrinsic epigenetic age acceleration; TGCT cis rs597539 0.652 rs569777 chr11:68706848 G/A cg21963583 chr11:68658836 MRPL21 0.37 6.08 0.48 1.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11080466 1.000 rs11080466 chr18:10899028 C/T cg02393756 chr18:9912783 VAPA 0.27 4.76 0.39 5.35e-6 Non-small cell lung cancer; TGCT cis rs9814567 1.000 rs1534026 chr3:134284767 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.18 -0.64 1.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs62380364 0.870 rs17559709 chr5:88149326 G/A cg22951263 chr5:87985283 NA -0.48 -4.62 -0.38 9.39e-6 Intelligence (multi-trait analysis); TGCT cis rs12643440 0.538 rs2041443 chr4:17137996 G/A cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs801193 1.000 rs7788576 chr7:66148302 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.14 -0.42 1.06e-6 Aortic root size; TGCT cis rs7786808 0.707 rs10247026 chr7:158230595 C/T cg01191920 chr7:158217561 PTPRN2 -0.44 -6.69 -0.51 7.02e-10 Obesity-related traits; TGCT cis rs67478160 0.619 rs55824307 chr14:104271207 C/T cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs17376456 0.935 rs13156002 chr5:93508931 G/A cg21475434 chr5:93447410 FAM172A 0.62 4.5 0.37 1.54e-5 Diabetic retinopathy; TGCT cis rs3806843 1.000 rs10053586 chr5:140210760 T/C cg19875535 chr5:140030758 IK 0.37 6.04 0.48 1.69e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2239547 0.563 rs6797399 chr3:52905917 G/A cg10802521 chr3:52805072 NEK4 -0.58 -5.46 -0.44 2.53e-7 Schizophrenia; TGCT cis rs796364 0.806 rs6743396 chr2:200860138 T/C cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT cis rs2050392 0.965 rs1543725 chr10:30698873 A/G cg18806716 chr10:30721971 MAP3K8 -0.53 -6.6 -0.51 1.07e-9 Inflammatory bowel disease; TGCT cis rs7614311 0.636 rs3846221 chr3:64008510 T/C cg22134162 chr3:63841271 THOC7 -0.5 -6.31 -0.49 4.61e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs3858526 0.883 rs11039686 chr11:5948725 T/C cg13902645 chr11:5959945 NA -0.46 -4.8 -0.4 4.54e-6 DNA methylation (variation); TGCT cis rs2012796 0.704 rs57670850 chr14:81841577 C/T cg02996355 chr14:81879375 NA 0.54 5.35 0.43 4.05e-7 Night sleep phenotypes; TGCT cis rs344364 0.511 rs1742472 chr16:1953040 A/G cg26617929 chr16:1858877 NA -0.26 -4.66 -0.39 8.04e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs75059851 0.756 rs55747998 chr11:133840793 C/T cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs9393692 0.967 rs6456712 chr6:26302573 A/C cg13736514 chr6:26305472 NA -0.43 -6.34 -0.49 3.98e-9 Educational attainment; TGCT cis rs9926296 0.744 rs6860 chr16:89711120 C/T cg01097406 chr16:89675127 NA 0.36 6.22 0.49 7.03e-9 Vitiligo; TGCT cis rs72781680 0.559 rs72796103 chr2:23900382 G/A cg08917208 chr2:24149416 ATAD2B 1.0 5.56 0.45 1.59e-7 Lymphocyte counts; TGCT cis rs11122272 0.735 rs2790881 chr1:231534181 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.64 -0.51 8.59e-10 Hemoglobin concentration; TGCT cis rs9902453 0.845 rs7209622 chr17:28256807 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.92 9.01 0.63 3.1e-15 Coffee consumption (cups per day); TGCT cis rs2857078 0.720 rs9906669 chr17:42305706 A/G cg19774624 chr17:42201019 HDAC5 -0.69 -7.14 -0.54 6.91e-11 Red cell distribution width;Reticulocyte count; TGCT cis rs17718580 0.793 rs113053719 chr14:50958256 C/A cg04730355 chr14:51134070 SAV1 0.99 5.36 0.43 3.97e-7 Cognitive performance; TGCT cis rs1005277 0.579 rs2505194 chr10:38393881 C/T cg13531842 chr10:38383804 ZNF37A -0.37 -4.46 -0.37 1.78e-5 Extrinsic epigenetic age acceleration; TGCT cis rs5769765 0.908 rs9616388 chr22:50313438 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.42 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs922182 0.569 rs72752984 chr15:64264082 G/T cg02919090 chr15:64263738 DAPK2 0.36 6.87 0.53 2.76e-10 Blood protein levels; TGCT cis rs62283056 0.636 rs17718958 chr4:6275735 G/A cg25554036 chr4:6271136 WFS1 -0.51 -4.71 -0.39 6.51e-6 Cisplatin-induced ototoxicity; TGCT cis rs57590327 0.508 rs9820349 chr3:81958587 A/G cg07356753 chr3:81810745 GBE1 -0.73 -6.76 -0.52 4.88e-10 Extraversion; TGCT cis rs2404602 0.692 rs55676827 chr15:76961716 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs910316 1.000 rs7142235 chr14:75559963 T/C cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs3784262 0.679 rs4238326 chr15:58336000 C/T cg12031962 chr15:58353849 ALDH1A2 0.55 8.56 0.61 3.56e-14 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2718812 0.766 rs12497513 chr3:133388670 C/G cg08048268 chr3:133502702 NA 0.38 4.76 0.39 5.38e-6 Iron status biomarkers; TGCT cis rs9649213 0.614 rs62479858 chr7:97924226 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.96 -8.87 -0.62 6.66e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs17761864 0.791 rs4362428 chr17:2090341 C/A cg02171503 chr17:1588363 PRPF8 -0.51 -5.04 -0.41 1.62e-6 Esophageal cancer (squamous cell); TGCT cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg02458000 chr6:26745757 NA -0.5 -4.55 -0.38 1.25e-5 Schizophrenia; TGCT cis rs6988636 1.000 rs16898086 chr8:124190445 A/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg09904177 chr6:26538194 HMGN4 0.68 6.27 0.49 5.41e-9 Intelligence (multi-trait analysis); TGCT cis rs9911578 1.000 rs2567911 chr17:56734977 A/G cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs33999310 chr3:52883332 G/A cg27565382 chr3:53032988 SFMBT1 0.49 4.47 0.37 1.75e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg17971929 chr21:40555470 PSMG1 0.98 9.51 0.65 1.95e-16 Cognitive function; TGCT cis rs7666738 0.546 rs28590002 chr4:98722642 C/T cg18180107 chr4:99064573 C4orf37 0.52 4.61 0.38 9.77e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6882046 0.513 rs447801 chr5:88002653 T/C cg24804195 chr5:87968844 LOC645323 -0.59 -5.71 -0.46 7.96e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs7208859 0.623 rs609063 chr17:28951513 A/G cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs7923452 0.507 rs103441 chr10:30778184 C/T cg13289132 chr10:30722225 MAP3K8 -0.42 -4.65 -0.39 8.47e-6 Itch intensity from mosquito bite; TGCT cis rs9399135 1.000 rs35123050 chr6:135302740 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.79 0.39 4.76e-6 Red blood cell count; TGCT cis rs854765 0.583 rs9904163 chr17:17830553 C/T cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs798766 1.000 rs798755 chr4:1720824 A/G cg05874882 chr4:1763078 NA -0.36 -4.87 -0.4 3.27e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.5 -4.78 -0.39 4.81e-6 Prudent dietary pattern; TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs6598955 0.543 rs12122527 chr1:26549748 C/T cg04990556 chr1:26633338 UBXN11 0.8 7.3 0.55 3.01e-11 Obesity-related traits; TGCT cis rs61931739 0.500 rs10844829 chr12:34304916 G/T cg06521331 chr12:34319734 NA -0.3 -4.46 -0.37 1.83e-5 Morning vs. evening chronotype; TGCT cis rs2354432 0.607 rs7537483 chr1:146709877 C/G cg25205988 chr1:146714368 CHD1L 1.18 4.82 0.4 4.2e-6 Mitochondrial DNA levels; TGCT cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg13395646 chr4:1353034 KIAA1530 -0.36 -4.75 -0.39 5.64e-6 Obesity-related traits; TGCT trans rs877282 1.000 rs12775643 chr10:773242 G/A cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg01238044 chr22:24384105 GSTT1 -0.54 -5.21 -0.42 7.52e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1577917 1.000 rs12664335 chr6:86597774 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.58 4.85 0.4 3.65e-6 Response to antipsychotic treatment; TGCT cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.89 0.4 3e-6 Platelet count; TGCT cis rs7937682 1.000 rs10789843 chr11:111576158 C/T cg09085632 chr11:111637200 PPP2R1B 1.07 9.76 0.66 4.89e-17 Primary sclerosing cholangitis; TGCT cis rs9638182 1.000 rs9638182 chr7:72999105 T/G cg14087351 chr7:73037990 MLXIPL -0.54 -4.53 -0.38 1.35e-5 Triglycerides; TGCT cis rs6831352 0.879 rs35146617 chr4:100066686 C/T cg12011299 chr4:100065546 ADH4 -0.46 -5.22 -0.42 7.38e-7 Alcohol dependence; TGCT cis rs8068544 0.818 rs79892925 chr17:40171819 A/G cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.08 -5.02 -0.41 1.75e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs13256369 1.000 rs1109619 chr8:8571616 G/T cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs4927850 0.958 rs1975582 chr3:195751439 G/T cg12923728 chr3:195709715 SDHAP1 -0.36 -7.57 -0.56 7.39e-12 Pancreatic cancer; TGCT cis rs11785400 0.731 rs4294163 chr8:143730830 G/T cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.79e-7 Schizophrenia; TGCT cis rs3784262 0.669 rs4646579 chr15:58329528 G/C cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.19 -0.49 7.94e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4253772 0.530 rs9615933 chr22:46677298 G/A cg24881330 chr22:46731750 TRMU 0.96 4.74 0.39 5.77e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.7 -0.46 8.36e-8 Coronary artery disease; TGCT cis rs7582180 0.663 rs930374 chr2:100962700 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.86 -0.4 3.52e-6 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg07061783 chr6:25882402 NA -0.41 -4.45 -0.37 1.89e-5 Height; TGCT cis rs11249608 0.636 rs62393070 chr5:178447943 A/G cg01312482 chr5:178451176 ZNF879 -0.58 -5.68 -0.45 8.97e-8 Pubertal anthropometrics; TGCT cis rs10464366 0.544 rs2280667 chr7:39172228 A/C cg15212455 chr7:39170539 POU6F2 0.34 7.63 0.57 5.29e-12 IgG glycosylation; TGCT cis rs611744 0.608 rs1448152 chr8:109278249 C/T cg21045802 chr8:109455806 TTC35 0.72 7.44 0.56 1.46e-11 Dupuytren's disease; TGCT cis rs6987853 0.933 rs2974355 chr8:42414117 C/T cg20539142 chr8:42623718 CHRNA6 -0.21 -5.1 -0.42 1.21e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs9894429 0.966 rs7405901 chr17:79587813 T/C cg21028142 chr17:79581711 NPLOC4 0.29 6.83 0.52 3.44e-10 Eye color traits; TGCT cis rs1005277 0.522 rs200943 chr10:38148730 A/G cg25427524 chr10:38739819 LOC399744 -0.37 -7.61 -0.56 5.93e-12 Extrinsic epigenetic age acceleration; TGCT cis rs826838 1.000 rs851934 chr12:39104453 G/T cg13010199 chr12:38710504 ALG10B -0.59 -4.91 -0.4 2.83e-6 Heart rate; TGCT cis rs9527 0.590 rs7089680 chr10:104802071 C/T cg15744005 chr10:104629667 AS3MT 0.4 4.63 0.38 9.04e-6 Arsenic metabolism; TGCT cis rs4285028 0.948 rs13083557 chr3:121687613 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs1577917 0.958 rs1545376 chr6:86504582 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.7 5.57 0.45 1.48e-7 Response to antipsychotic treatment; TGCT cis rs12549902 0.800 rs7825494 chr8:41507350 C/T cg00088007 chr8:41504566 NKX6-3 0.31 4.79 0.39 4.72e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs1577917 1.000 rs10498958 chr6:86649705 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.65 5.36 0.43 3.86e-7 Response to antipsychotic treatment; TGCT cis rs7216064 0.953 rs11871285 chr17:65840809 G/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7943203 0.568 rs228593 chr11:108141134 G/A cg04873221 chr11:107992290 ACAT1 -0.61 -4.96 -0.41 2.3e-6 Red blood cell count;Mean corpuscular volume; TGCT cis rs7267979 1.000 rs6050547 chr20:25326012 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3087591 0.960 rs2952995 chr17:29541061 T/C cg24425628 chr17:29625626 OMG;NF1 0.45 7.11 0.54 8.22e-11 Hip circumference; TGCT cis rs9527 0.590 rs2148198 chr10:104915310 A/G cg15744005 chr10:104629667 AS3MT 0.42 4.9 0.4 2.96e-6 Arsenic metabolism; TGCT cis rs3784262 0.631 rs4646560 chr15:58353546 C/G cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7772486 0.686 rs7744014 chr6:146123818 G/A cg23711669 chr6:146136114 FBXO30 0.86 9.53 0.65 1.74e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs5750830 0.621 rs5750810 chr22:39792943 A/G cg05872129 chr22:39784769 NA -1.03 -11.23 -0.71 1.28e-20 Intelligence (multi-trait analysis); TGCT cis rs10782582 0.593 rs4638068 chr1:76161663 G/A cg03433033 chr1:76189801 ACADM -0.65 -7.41 -0.55 1.67e-11 Daytime sleep phenotypes; TGCT cis rs6089829 0.643 rs6011545 chr20:61660038 G/A cg03213289 chr20:61660250 NA 0.58 6.8 0.52 4.01e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs80282103 0.618 rs74117849 chr10:1165425 A/G cg08668510 chr10:1095578 IDI1 1.07 5.04 0.41 1.59e-6 Glomerular filtration rate (creatinine); TGCT cis rs8056742 0.643 rs11644003 chr16:85099836 A/G cg00229868 chr16:85520891 NA 0.38 4.73 0.39 6.13e-6 Amyotrophic lateral sclerosis; TGCT cis rs16867321 1.000 rs16867330 chr2:181446202 T/G cg23363182 chr2:181467187 NA -0.39 -5.47 -0.44 2.38e-7 Obesity; TGCT cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg17054783 chr10:134559939 INPP5A 0.24 4.83 0.4 3.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4664308 1.000 rs4664308 chr2:160917497 A/G cg03641300 chr2:160917029 PLA2R1 -0.27 -6.58 -0.51 1.2e-9 Idiopathic membranous nephropathy; TGCT cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg18654377 chr3:49208889 KLHDC8B -0.37 -4.91 -0.4 2.78e-6 Menarche (age at onset); TGCT cis rs936229 0.749 rs6495126 chr15:75175026 C/T cg10253484 chr15:75165896 SCAMP2 0.74 6.26 0.49 5.63e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs9788333 0.962 rs34853044 chr13:21883784 C/T cg22663859 chr13:21900854 NA 0.36 4.99 0.41 1.97e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs2730260 0.537 rs73169246 chr7:158890593 C/T cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs10782582 0.569 rs2131557 chr1:76388589 A/C cg05598546 chr1:76251766 SNORD45C;RABGGTB -0.56 -4.88 -0.4 3.16e-6 Daytime sleep phenotypes; TGCT cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg20607798 chr8:58055168 NA 0.49 4.52 0.38 1.43e-5 Developmental language disorder (linguistic errors); TGCT cis rs4788570 0.538 rs59364668 chr16:71569229 A/T cg06353428 chr16:71660113 MARVELD3 -1.33 -7.63 -0.57 5.33e-12 Intelligence (multi-trait analysis); TGCT cis rs854765 0.547 rs8069811 chr17:17922280 G/A cg09796270 chr17:17721594 SREBF1 0.25 5.03 0.41 1.71e-6 Total body bone mineral density; TGCT cis rs16958440 0.867 rs114475395 chr18:44691010 A/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs838147 0.563 rs281379 chr19:49214274 C/T cg04599840 chr19:48886497 KDELR1 0.22 4.59 0.38 1.08e-5 Dietary macronutrient intake; TGCT cis rs7582180 0.701 rs11693044 chr2:100922313 T/C cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10802346 0.636 rs12047380 chr1:246394817 C/T cg11377642 chr1:245534889 KIF26B -0.25 -4.44 -0.37 1.94e-5 Fractional exhaled nitric oxide (childhood); TGCT cis rs9419702 0.568 rs11156445 chr10:133542301 T/C cg04492858 chr10:133558786 NA 0.54 5.81 0.46 4.93e-8 Survival in rectal cancer; TGCT cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.91 6.41 0.5 2.79e-9 Gut microbiome composition (summer); TGCT cis rs9527 0.637 rs7096169 chr10:104618695 A/G cg15744005 chr10:104629667 AS3MT -0.49 -6.32 -0.49 4.34e-9 Arsenic metabolism; TGCT cis rs11096990 0.656 rs4580661 chr4:39296350 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs56104184 0.775 rs73063505 chr19:49402765 T/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs208520 0.661 rs207111 chr6:66792513 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs9486715 0.867 rs4839687 chr6:96951732 C/A cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs12142240 0.731 rs6658556 chr1:46844180 A/C cg00530320 chr1:46809349 NSUN4 0.27 5.55 0.45 1.68e-7 Menopause (age at onset); TGCT cis rs11190604 1.000 rs11190596 chr10:102293238 C/G cg23241863 chr10:102295624 HIF1AN 0.63 4.63 0.38 9.22e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2439831 0.867 rs3809481 chr15:43662829 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.08 7.96 0.58 9.31e-13 Lung cancer in ever smokers; TGCT cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs7568458 0.709 rs2043675 chr2:85769975 C/T cg02493740 chr2:85810744 VAMP5 0.28 5.24 0.43 6.55e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6684514 1.000 rs10908500 chr1:156280671 A/T cg16558208 chr1:156270281 VHLL 0.48 9.86 0.66 2.71e-17 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs858239 0.704 rs199657 chr7:23337507 G/C cg05602783 chr7:23145260 KLHL7 0.72 5.72 0.46 7.3900000000000007e-08 Cerebrospinal fluid biomarker levels; TGCT cis rs514406 0.763 rs9988539 chr1:53213884 T/C cg25767906 chr1:53392781 SCP2 0.48 5.36 0.43 3.95e-7 Monocyte count; TGCT cis rs7772486 0.875 rs10457796 chr6:146416087 T/G cg05347473 chr6:146136440 FBXO30 0.56 5.1 0.42 1.24e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs59751489 chr4:98933802 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.840 rs12905223 chr15:85114268 T/C cg11189052 chr15:85197271 WDR73 0.77 6.44 0.5 2.34e-9 Schizophrenia; TGCT cis rs4144743 1.000 rs4144746 chr17:45323355 C/G cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs9611565 0.649 rs4822050 chr22:42177453 C/G cg13695892 chr22:41940480 POLR3H -0.79 -7.5 -0.56 1.07e-11 Vitiligo; TGCT cis rs910316 0.935 rs175076 chr14:75505486 A/G cg11812906 chr14:75593930 NEK9 -0.73 -7.17 -0.54 6.01e-11 Height; TGCT cis rs10791097 0.677 rs11222359 chr11:130730648 A/G cg14779329 chr11:130786720 SNX19 0.26 4.55 0.38 1.25e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs78487399 0.808 rs13405158 chr2:43705286 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.42 5.56 0.45 1.57e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs28595532 0.688 rs116173135 chr4:119721949 C/T cg14228332 chr4:119757509 SEC24D 1.38 6.91 0.53 2.21e-10 Cannabis dependence symptom count; TGCT cis rs2463822 1.000 rs2463822 chr11:62103420 T/C cg23876832 chr11:62092739 NA 0.65 4.56 0.38 1.19e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs28595532 0.920 rs115530096 chr4:119760512 T/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7731657 0.537 rs13355897 chr5:130360622 G/A cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs7611238 0.560 rs9836665 chr3:195113176 G/A cg27323046 chr3:195102265 ACAP2 0.39 5.17 0.42 8.93e-7 Body mass index; TGCT cis rs3099143 1.000 rs7172639 chr15:77165288 G/A cg21673338 chr15:77095150 SCAPER 0.52 5.05 0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs9329221 0.772 rs7824675 chr8:10243418 G/T cg21775007 chr8:11205619 TDH -0.49 -4.77 -0.39 5.14e-6 Neuroticism; TGCT cis rs9357506 0.905 rs4714927 chr6:46309789 A/T cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs4953076 0.573 rs6544746 chr2:44407985 C/T cg04920474 chr2:44395004 PPM1B 0.58 5.77 0.46 5.91e-8 Height; TGCT cis rs3733585 0.638 rs6414766 chr4:9956474 G/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.962 rs17550217 chr4:98999699 T/A cg17366294 chr4:99064904 C4orf37 0.76 6.94 0.53 1.91e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg17178900 chr1:205818956 PM20D1 0.58 7.21 0.54 4.81e-11 Menarche (age at onset); TGCT cis rs9902453 0.845 rs7221516 chr17:28232506 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.92 9.1 0.63 1.88e-15 Coffee consumption (cups per day); TGCT cis rs13082711 0.954 rs35523848 chr3:27552800 A/C cg02860705 chr3:27208620 NA 0.33 4.56 0.38 1.21e-5 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7133214 0.510 rs4931479 chr12:27948615 A/G cg12166080 chr12:27706343 PPFIBP1 0.24 5.0 0.41 1.94e-6 Gut microbiota (functional units); TGCT cis rs2832191 0.716 rs8132085 chr21:30501389 G/T cg24692254 chr21:30365293 RNF160 -0.91 -10.24 -0.68 3.22e-18 Dental caries; TGCT cis rs7674212 0.570 rs2126470 chr4:104061762 T/C cg16532752 chr4:104119610 CENPE -0.63 -5.69 -0.45 8.85e-8 Type 2 diabetes; TGCT cis rs425277 0.958 rs262652 chr1:2090816 T/C cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs7523273 0.565 rs2796251 chr1:207903688 C/G cg22525895 chr1:207977042 MIR29B2 -0.33 -5.33 -0.43 4.38e-7 Schizophrenia; TGCT cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg14983838 chr19:29218262 NA 0.83 6.85 0.52 3.07e-10 Methadone dose in opioid dependence; TGCT cis rs514406 0.679 rs541852 chr1:53256834 A/G cg01802117 chr1:53393560 SCP2 0.49 5.94 0.47 2.62e-8 Monocyte count; TGCT cis rs9329221 0.905 rs4841329 chr8:10253098 A/G cg21775007 chr8:11205619 TDH -0.53 -4.79 -0.4 4.58e-6 Neuroticism; TGCT cis rs11030122 0.702 rs17279635 chr11:3973083 A/C cg18678763 chr11:4115507 RRM1 0.49 6.13 0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs931127 0.502 rs1466462 chr11:65419364 C/G cg17480646 chr11:65405466 SIPA1 0.54 6.84 0.52 3.29e-10 Systemic lupus erythematosus; TGCT cis rs492146 0.765 rs316129 chr6:52848905 C/T cg06706454 chr6:52930286 FBXO9 -0.53 -4.95 -0.41 2.37e-6 Epilepsy (remission after treatment); TGCT cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.57 5.14 0.42 1.03e-6 Height; TGCT cis rs11190604 1.000 rs2495736 chr10:102338410 T/C cg23241863 chr10:102295624 HIF1AN 0.67 4.9 0.4 2.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2070488 0.804 rs13092473 chr3:38458958 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.79 7.97 0.58 8.75e-13 Electrocardiographic conduction measures; TGCT cis rs4720575 1.000 rs4720575 chr7:47086805 A/G cg00036614 chr7:47093842 NA -0.2 -5.08 -0.42 1.35e-6 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.19 -0.54 5.3e-11 Colorectal cancer; TGCT cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg00475322 chr7:917719 C7orf20 0.5 6.38 0.5 3.17e-9 Perceived unattractiveness to mosquitoes; TGCT cis rs2361718 0.500 rs4889818 chr17:78085228 A/G cg27614120 chr17:77386099 HRNBP3 0.27 4.77 0.39 5.1e-6 Yeast infection; TGCT cis rs28595532 0.920 rs17258830 chr4:119725543 A/T cg14228332 chr4:119757509 SEC24D -1.38 -6.93 -0.53 2.07e-10 Cannabis dependence symptom count; TGCT cis rs10782582 0.546 rs79652169 chr1:76233882 G/A cg03433033 chr1:76189801 ACADM -0.55 -6.05 -0.48 1.61e-8 Daytime sleep phenotypes; TGCT cis rs3782455 0.793 rs2290798 chr12:114404143 C/T cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs17741873 0.836 rs57771499 chr10:75605492 T/C cg07699608 chr10:75541558 CHCHD1 0.71 4.81 0.4 4.26e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg02458000 chr6:26745757 NA 0.49 4.45 0.37 1.92e-5 Schizophrenia; TGCT cis rs7539542 0.556 rs10753928 chr1:202891045 A/C cg22008490 chr1:202129255 PTPN7 -0.19 -4.48 -0.37 1.66e-5 Mean platelet volume; TGCT cis rs1348850 0.793 rs13000048 chr2:178337089 C/A cg22681709 chr2:178499509 PDE11A -0.38 -4.98 -0.41 2.1e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4789294 0.806 rs7210520 chr17:74450040 C/T cg17540765 chr17:73631586 RECQL5;LOC643008 0.24 4.43 0.37 2.02e-5 Lymphocyte percentage of white cells; TGCT cis rs1008375 0.966 rs11947836 chr4:17697187 A/G cg18681998 chr4:17616180 MED28 -0.82 -7.49 -0.56 1.1e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs981844 0.775 rs17299211 chr4:154738284 G/A cg14289246 chr4:154710475 SFRP2 1.01 8.88 0.62 6.23e-15 Response to statins (LDL cholesterol change); TGCT cis rs67385638 1.000 rs2855039 chr11:5271671 C/T cg12559170 chr11:5275217 HBG2 0.47 9.09 0.63 1.96e-15 Hemoglobin levels; TGCT cis rs9467773 1.000 rs6925895 chr6:26572165 G/T cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs1008375 1.000 rs10939743 chr4:17662731 G/A cg16339924 chr4:17578868 LAP3 0.55 4.74 0.39 5.88e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2721195 0.845 rs756627 chr8:145737286 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 0.88 9.27 0.64 7.39e-16 Age at first birth; TGCT cis rs6540559 0.551 rs17389436 chr1:209972297 A/T cg22029157 chr1:209979665 IRF6 0.81 4.97 0.41 2.19e-6 Cleft lip with or without cleft palate; TGCT cis rs6752107 0.967 rs3792109 chr2:234184417 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.73 0.39 6.08e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7226408 0.894 rs11659465 chr18:34375487 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.56 0.38 1.2e-5 Obesity-related traits; TGCT cis rs735396 0.770 rs1169314 chr12:121443116 A/G cg15155738 chr12:121454335 C12orf43 0.55 4.79 0.4 4.71e-6 N-glycan levels; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs13177918 0.686 rs12654827 chr5:149822090 T/C cg14059543 chr5:149831962 NA -0.73 -9.52 -0.65 1.79e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12989701 0.778 rs7583814 chr2:127863029 C/T cg08168897 chr2:127865431 BIN1 0.55 6.04 0.48 1.67e-8 Alzheimer's disease (late onset); TGCT cis rs59698941 0.527 rs1032764 chr5:132185419 A/C cg21474247 chr5:131268130 NA 0.32 4.98 0.41 2.12e-6 Apolipoprotein A-IV levels; TGCT cis rs10782582 0.593 rs12131344 chr1:76136437 C/T cg03433033 chr1:76189801 ACADM -0.65 -7.15 -0.54 6.51e-11 Daytime sleep phenotypes; TGCT cis rs1577917 0.958 rs4707236 chr6:86583967 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.71e-7 Response to antipsychotic treatment; TGCT cis rs6815814 0.861 rs12233670 chr4:38787216 C/T cg02016764 chr4:38805732 TLR1 -0.27 -4.58 -0.38 1.14e-5 Breast cancer; TGCT cis rs7089973 0.584 rs7908665 chr10:116611337 G/A cg03647239 chr10:116582469 FAM160B1 0.61 5.86 0.47 3.87e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs904251 0.600 rs12211110 chr6:37466232 A/G cg08126542 chr6:37504118 NA -0.41 -5.76 -0.46 6.27e-8 Cognitive performance; TGCT cis rs2070488 0.965 rs35553573 chr3:38441439 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 9.62 0.65 1.08e-16 Electrocardiographic conduction measures; TGCT cis rs6570726 0.791 rs11155433 chr6:145907831 A/G cg23711669 chr6:146136114 FBXO30 -0.88 -9.64 -0.65 9.44e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs35883536 0.647 rs10493929 chr1:101043928 A/C cg14855972 chr1:101004472 GPR88 -0.24 -4.52 -0.38 1.45e-5 Monocyte count; TGCT cis rs617219 0.737 rs2166343 chr5:78484060 A/G cg05890484 chr5:78407552 BHMT 0.39 5.34 0.43 4.28e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2354432 0.607 rs4950310 chr1:146659964 A/G cg25205988 chr1:146714368 CHD1L 1.29 5.46 0.44 2.46e-7 Mitochondrial DNA levels; TGCT cis rs7727544 0.594 rs10479000 chr5:131607402 T/C cg21474247 chr5:131268130 NA 0.3 4.52 0.38 1.41e-5 Blood metabolite levels; TGCT cis rs7568458 0.905 rs6714709 chr2:85756375 C/G cg02493740 chr2:85810744 VAMP5 -0.27 -4.84 -0.4 3.72e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg09177884 chr7:1199841 ZFAND2A 0.55 5.35 0.43 4.08e-7 Longevity;Endometriosis; TGCT cis rs137699 0.687 rs4821887 chr22:39756985 C/T cg24399712 chr22:39784796 NA -0.74 -6.45 -0.5 2.23e-9 IgG glycosylation; TGCT cis rs35146811 0.657 rs36019559 chr7:99814586 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs9527 0.662 rs4919687 chr10:104595248 G/A cg15744005 chr10:104629667 AS3MT -0.46 -5.74 -0.46 7e-8 Arsenic metabolism; TGCT cis rs6121246 0.567 rs6120879 chr20:30202961 T/C cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs933688 1.000 rs12655973 chr5:90736537 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.07 9.6 0.65 1.2e-16 Smoking behavior; TGCT cis rs7772486 0.790 rs6923545 chr6:146244743 A/G cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT trans rs3780486 0.718 rs10971418 chr9:33122024 A/C cg04842962 chr6:43655489 MRPS18A -1.06 -7.83 -0.58 1.91e-12 IgG glycosylation; TGCT cis rs9811920 0.809 rs13059754 chr3:99678490 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.47 5.36 0.43 3.91e-7 Axial length; TGCT cis rs2227564 0.597 rs12256103 chr10:75545251 A/G cg19442545 chr10:75533431 FUT11 -0.3 -4.48 -0.37 1.7e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg06618935 chr21:46677482 NA -0.36 -5.47 -0.44 2.38e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg16423285 chr20:60520624 NA -0.69 -7.33 -0.55 2.58e-11 Body mass index; TGCT cis rs12477438 0.520 rs13022329 chr2:99731189 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs6770219 0.516 rs7613043 chr3:186134719 A/G cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs3617 0.625 rs2240915 chr3:52859526 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.6 -0.38 1.02e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7412746 0.566 rs2864871 chr1:150766964 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg17345569 chr6:42928274 GNMT -0.46 -4.77 -0.39 5.03e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs854765 0.547 rs7209003 chr17:17907393 T/A cg04398451 chr17:18023971 MYO15A -0.3 -4.84 -0.4 3.73e-6 Total body bone mineral density; TGCT cis rs9467711 0.606 rs2073530 chr6:26375243 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.765 rs6737257 chr2:99683330 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs10769945 0.679 rs2137322 chr11:1917354 A/G cg06503573 chr11:1949039 TNNT3 -0.26 -4.99 -0.41 2e-6 DNA methylation (variation); TGCT cis rs546131 0.928 rs483976 chr11:34840167 C/G cg06937548 chr11:34938143 PDHX;APIP 0.62 5.61 0.45 1.24e-7 Lung disease severity in cystic fibrosis; TGCT cis rs4961252 0.505 rs6990155 chr8:142098977 C/T cg09914555 chr8:142094789 NA 0.42 6.53 0.51 1.54e-9 Isovolumetric relaxation time;Response to interferon beta therapy; TGCT cis rs2734839 0.537 rs10891549 chr11:113278447 T/C cg14159747 chr11:113255604 NA 0.39 4.96 0.41 2.31e-6 Information processing speed; TGCT cis rs1421811 0.532 rs72740626 chr5:32692220 G/C cg16267343 chr5:32710456 NPR3 0.74 6.53 0.51 1.56e-9 Blood pressure; TGCT cis rs13315871 1.000 rs13071688 chr3:58398730 G/A cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs751728 1.000 rs6925273 chr6:33732448 A/G cg13859433 chr6:33739653 LEMD2 -0.39 -7.36 -0.55 2.26e-11 Crohn's disease; TGCT cis rs7772486 0.686 rs1004752 chr6:146037822 G/A cg23711669 chr6:146136114 FBXO30 -0.88 -9.77 -0.66 4.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs546131 0.928 rs572690 chr11:34833614 A/G cg11058730 chr11:34937778 PDHX;APIP 0.52 4.58 0.38 1.12e-5 Lung disease severity in cystic fibrosis; TGCT cis rs826838 1.000 rs10880785 chr12:38655405 T/G cg26384229 chr12:38710491 ALG10B 1.05 10.25 0.68 3.18e-18 Heart rate; TGCT cis rs9611565 0.512 rs139572 chr22:42214532 C/T cg06481639 chr22:41940642 POLR3H -0.69 -6.02 -0.48 1.83e-8 Vitiligo; TGCT cis rs13217239 0.646 rs12523820 chr6:27001502 A/G cg15659132 chr6:26577336 NA 0.54 5.44 0.44 2.78e-7 Schizophrenia; TGCT cis rs6089829 0.925 rs13041507 chr20:61666180 T/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs909674 0.541 rs5750812 chr22:39793079 G/A cg05872129 chr22:39784769 NA -0.99 -11.6 -0.72 1.61e-21 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7017914 0.652 rs10957533 chr8:71825107 C/T cg27287166 chr8:71315034 NCOA2 0.48 4.44 0.37 1.94e-5 Bone mineral density; TGCT cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg07061783 chr6:25882402 NA -0.48 -5.32 -0.43 4.58e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs13145011 chr4:98993410 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4975616 0.771 rs3816659 chr5:1317820 A/G cg07493874 chr5:1342172 CLPTM1L 0.26 6.22 0.49 6.98e-9 Lung cancer; TGCT cis rs9311474 1.000 rs2276834 chr3:52325759 A/G cg10802521 chr3:52805072 NEK4 -0.59 -6.4 -0.5 2.91e-9 Electroencephalogram traits; TGCT cis rs151997 0.671 rs395557 chr5:50215832 G/T cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs7100689 0.725 rs2487074 chr10:82064104 A/G cg01528321 chr10:82214614 TSPAN14 0.8 7.91 0.58 1.25e-12 Post bronchodilator FEV1; TGCT cis rs1218582 0.741 rs4339857 chr1:154888962 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs3806843 0.576 rs246021 chr5:140334504 C/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7017914 0.934 rs13255152 chr8:71859619 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.07 -0.41 1.39e-6 Bone mineral density; TGCT cis rs6088580 0.608 rs1205342 chr20:32921842 C/T cg06115741 chr20:33292138 TP53INP2 -0.55 -4.84 -0.4 3.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs265548 0.608 rs265544 chr19:17903479 G/C cg03316864 chr19:17906309 B3GNT3 0.43 4.95 0.41 2.36e-6 Tumor biomarkers; TGCT cis rs7044106 0.718 rs1960421 chr9:123394894 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.93 0.4 2.59e-6 Hip circumference adjusted for BMI; TGCT cis rs12291225 0.679 rs1043237 chr11:14289053 A/T cg19336497 chr11:14380999 RRAS2 -0.38 -5.8 -0.46 5.09e-8 Sense of smell; TGCT trans rs4765905 0.522 rs2283291 chr12:2337460 G/A cg13866577 chr1:66797481 PDE4B -0.5 -6.96 -0.53 1.78e-10 Schizophrenia; TGCT cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs9581857 0.725 rs1924074 chr13:28015387 C/G cg22138327 chr13:27999177 GTF3A -0.79 -5.5 -0.44 2.1e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs1355223 0.583 rs2941043 chr11:34870994 A/G cg11058730 chr11:34937778 PDHX;APIP -0.77 -8.18 -0.59 2.92e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs7568458 0.684 rs67988001 chr2:85787123 C/T cg17127132 chr2:85788382 GGCX 0.5 4.55 0.38 1.28e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2153535 0.580 rs9393023 chr6:8469994 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7618915 1.000 rs34569561 chr3:52287293 T/C cg10802521 chr3:52805072 NEK4 -0.5 -5.3 -0.43 5.02e-7 Bipolar disorder; TGCT cis rs4665809 1.000 rs1560868 chr2:26281459 A/T cg25036284 chr2:26402008 FAM59B 0.54 4.88 0.4 3.15e-6 Gut microbiome composition (summer); TGCT cis rs17376456 1.000 rs13174700 chr5:93554644 G/A cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.72e-12 Diabetic retinopathy; TGCT trans rs7819412 0.534 rs11250113 chr8:10907479 C/T cg15556689 chr8:8085844 FLJ10661 0.72 6.82 0.52 3.6e-10 Triglycerides; TGCT cis rs1472147 0.503 rs58691638 chr7:128433690 A/T cg00260937 chr7:128520193 KCP 0.43 4.89 0.4 3.09e-6 Calcium levels; TGCT cis rs6495122 0.699 rs1378942 chr15:75077367 A/C cg10253484 chr15:75165896 SCAMP2 0.68 6.01 0.48 1.87e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs6788895 0.661 rs60259684 chr3:150494951 A/G cg07663535 chr3:150480033 SIAH2 0.96 4.49 0.37 1.6e-5 Breast cancer; TGCT cis rs9914988 0.943 rs2043031 chr17:27085564 A/G cg20469991 chr17:27169893 C17orf63 -0.79 -5.51 -0.44 1.97e-7 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7666738 0.830 rs2865949 chr4:99039967 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6121246 0.909 rs6058460 chr20:30363071 G/A cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT trans rs17471911 0.708 rs11189940 chr10:100782356 A/G cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs9400467 0.537 rs584937 chr6:111481577 T/G cg15721981 chr6:111408429 SLC16A10 0.68 4.48 0.37 1.69e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg06873352 chr17:61820015 STRADA 0.57 6.14 0.48 1.02e-8 Prudent dietary pattern; TGCT cis rs2456568 0.741 rs9633811 chr11:93628327 A/G cg17595323 chr11:93583763 C11orf90 0.46 6.48 0.5 1.99e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs453301 0.653 rs7016139 chr8:8895470 A/G cg15556689 chr8:8085844 FLJ10661 -0.79 -7.43 -0.56 1.53e-11 Joint mobility (Beighton score); TGCT cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg06481639 chr22:41940642 POLR3H 0.74 6.59 0.51 1.11e-9 Vitiligo; TGCT cis rs74181299 0.571 rs71424153 chr2:65280894 G/C cg05010058 chr2:65284262 CEP68 0.49 5.01 0.41 1.79e-6 Pulse pressure; TGCT cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg22166914 chr1:53195759 ZYG11B -0.46 -8.42 -0.6 7.72e-14 Monocyte count; TGCT cis rs7582180 0.602 rs7585582 chr2:100998030 G/C cg14675211 chr2:100938903 LONRF2 0.47 4.45 0.37 1.89e-5 Intelligence (multi-trait analysis); TGCT cis rs7568458 0.684 rs7579147 chr2:85805654 G/A cg02493740 chr2:85810744 VAMP5 -0.29 -5.51 -0.44 1.94e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9796 0.866 rs692155 chr15:41407061 A/G cg18705301 chr15:41695430 NDUFAF1 -0.46 -5.94 -0.47 2.62e-8 Menopause (age at onset); TGCT cis rs910187 0.631 rs62201431 chr20:45810994 G/A cg27589058 chr20:45804311 EYA2 -0.37 -7.89 -0.58 1.32e-12 Migraine; TGCT cis rs548181 0.736 rs540723 chr11:125489621 A/G cg03464685 chr11:125439445 EI24 1.12 7.9 0.58 1.27e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2050392 0.517 rs619864 chr10:30750950 A/G cg13289132 chr10:30722225 MAP3K8 0.42 5.18 0.42 8.55e-7 Inflammatory bowel disease; TGCT trans rs17684571 0.938 rs13206849 chr6:56566621 T/C cg14229071 chr15:89282588 NA 0.52 6.82 0.52 3.54e-10 Schizophrenia; TGCT cis rs9534288 0.797 rs9526134 chr13:46618046 G/T cg15192986 chr13:46630673 CPB2 -0.5 -7.06 -0.54 1.07e-10 Blood protein levels; TGCT cis rs7647973 0.626 rs1996664 chr3:49878395 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.83 -0.4 3.96e-6 Menarche (age at onset); TGCT cis rs9883204 0.904 rs11717195 chr3:123082398 C/T cg04890266 chr3:123102914 ADCY5 -0.35 -4.88 -0.4 3.2e-6 Birth weight; TGCT cis rs61931739 0.500 rs12146843 chr12:34451738 T/G cg06521331 chr12:34319734 NA -0.28 -4.52 -0.38 1.4e-5 Morning vs. evening chronotype; TGCT cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg13683864 chr3:40499215 RPL14 -1.18 -12.86 -0.76 1.47e-24 Renal cell carcinoma; TGCT cis rs2549003 0.966 rs839 chr5:131819126 C/T cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.92e-6 Asthma (sex interaction); TGCT cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs2721195 0.874 rs2721197 chr8:145727705 A/G cg11211951 chr8:145729740 GPT 0.27 6.49 0.5 1.9e-9 Age at first birth; TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs904251 0.861 rs1776456 chr6:37484698 C/G cg01843034 chr6:37503916 NA -0.51 -6.24 -0.49 6.23e-9 Cognitive performance; TGCT cis rs2467099 0.504 rs2666005 chr17:73944596 T/G cg10108402 chr17:73901394 MRPL38 -0.47 -4.61 -0.38 1e-5 Systolic blood pressure; TGCT cis rs514406 0.525 rs269291 chr1:53189297 C/T cg25767906 chr1:53392781 SCP2 -0.45 -4.89 -0.4 3.09e-6 Monocyte count; TGCT cis rs9517302 0.847 rs9517297 chr13:99094961 A/C cg22223119 chr13:99095684 FARP1 -0.69 -8.58 -0.61 3.27e-14 Obesity-related traits; TGCT cis rs556990 0.760 rs3024739 chr13:113819948 G/A cg18105134 chr13:113819100 PROZ -0.47 -7.85 -0.58 1.64e-12 Blood protein levels; TGCT cis rs2836974 1.000 rs28360661 chr21:40681972 G/C cg11644478 chr21:40555479 PSMG1 0.96 9.3 0.64 6.17e-16 Cognitive function; TGCT cis rs6964587 1.000 rs1859037 chr7:91568272 A/G cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs2996428 0.667 rs16824230 chr1:3766240 A/G cg17848003 chr1:3704513 LRRC47 0.2 5.49 0.44 2.21e-7 Red cell distribution width; TGCT cis rs1171582 0.692 rs2671611 chr10:61491646 C/T cg23572703 chr10:62241191 NA 0.3 4.96 0.41 2.27e-6 Alopecia areata; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg04234412 chr22:24373322 LOC391322 -0.93 -11.97 -0.73 2.05e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1153858 1.000 rs11858495 chr15:45637662 A/G cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.19 -0.42 8.25e-7 Homoarginine levels; TGCT cis rs4653767 1.000 rs4653767 chr1:226916078 T/C cg10327440 chr1:227177885 CDC42BPA -0.46 -4.89 -0.4 3.08e-6 Parkinson's disease; TGCT cis rs12497850 0.931 rs7647813 chr3:48833348 G/T cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs7267979 0.718 rs2983489 chr20:25244120 C/A cg03522245 chr20:25566470 NINL 0.52 5.4 0.44 3.22e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1218582 0.774 rs1007170 chr1:154881461 G/A cg16680214 chr1:154839983 KCNN3 -0.42 -9.25 -0.64 8.37e-16 Prostate cancer; TGCT cis rs3008870 1.000 rs975451 chr1:67480060 T/C cg03991309 chr1:68237761 GNG12 0.27 4.49 0.37 1.6e-5 Lymphocyte percentage of white cells; TGCT cis rs72768842 1.000 rs60449834 chr5:78957986 G/A cg24834873 chr5:79865402 ANKRD34B -1.16 -4.61 -0.38 9.84e-6 Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs1008375 0.966 rs2010053 chr4:17583806 A/C cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11718455 0.960 rs11921942 chr3:44007957 T/C cg08738300 chr3:44038990 NA 0.86 6.55 0.51 1.4e-9 Coronary artery disease; TGCT cis rs7918232 0.574 rs10458708 chr10:27455605 C/T cg14442939 chr10:27389572 ANKRD26 0.98 9.72 0.66 5.87e-17 Breast cancer; TGCT cis rs2235642 0.928 rs56289115 chr16:1608934 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.29 -5.22 -0.42 7.33e-7 Coronary artery disease; TGCT cis rs7917772 0.582 rs4917978 chr10:104366353 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.61 -6.01 -0.47 1.94e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs1062177 0.756 rs2964591 chr5:151117397 A/G cg12924095 chr5:151150029 G3BP1 -0.34 -4.59 -0.38 1.08e-5 Preschool internalizing problems; TGCT trans rs7507204 0.530 rs4807469 chr19:3443382 G/C cg08382705 chr11:45687319 CHST1 -0.79 -7.8 -0.57 2.22e-12 Height; TGCT cis rs9325144 0.555 rs7301258 chr12:38706942 C/T cg26384229 chr12:38710491 ALG10B 0.69 6.4 0.5 2.84e-9 Morning vs. evening chronotype; TGCT cis rs7017914 0.967 rs34677078 chr8:71617715 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs909002 0.849 rs10798881 chr1:32101775 G/C cg13919466 chr1:32135498 COL16A1 -0.32 -4.46 -0.37 1.8e-5 Intelligence (multi-trait analysis); TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg01171360 chr6:293285 DUSP22 -0.78 -7.84 -0.58 1.81e-12 Menopause (age at onset); TGCT cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg03452623 chr4:187889614 NA -0.38 -5.7 -0.46 8.09e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6725041 0.846 rs10185271 chr2:213089454 T/G cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs78487399 0.908 rs12474030 chr2:43812317 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs1075232 0.677 rs72714666 chr15:31492226 T/C cg27417677 chr7:130130918 MESTIT1;MEST 0.94 6.68 0.51 7.11e-10 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg22166914 chr1:53195759 ZYG11B 0.36 5.96 0.47 2.45e-8 Monocyte count; TGCT cis rs7772486 0.719 rs4391282 chr6:146276780 A/T cg23711669 chr6:146136114 FBXO30 -0.85 -9.51 -0.65 1.95e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs155076 1.000 rs567166 chr13:21837519 T/C cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT trans rs7824557 0.564 rs2572389 chr8:11236392 T/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs4953076 0.573 rs920519 chr2:44452344 T/C cg04920474 chr2:44395004 PPM1B 0.6 6.02 0.48 1.81e-8 Height; TGCT cis rs2013441 1.000 rs2703780 chr17:20143672 A/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs3892630 0.588 rs28787932 chr19:33226229 T/C cg22980127 chr19:33182716 NUDT19 0.76 6.28 0.49 5.32e-9 Red blood cell traits; TGCT cis rs853679 0.546 rs200995 chr6:27813694 C/T cg10876282 chr6:28092338 ZSCAN16 -0.74 -4.44 -0.37 1.98e-5 Depression; TGCT cis rs12134133 1.000 rs2564973 chr1:207480104 T/C cg02152968 chr1:207494213 CD55 0.62 4.89 0.4 3.05e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs1215050 0.605 rs28479339 chr4:98604485 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11696501 0.637 rs2093090 chr20:44205464 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.62 -0.38 9.32e-6 Brain structure; TGCT cis rs7829975 0.846 rs7005216 chr8:8547110 C/G cg15556689 chr8:8085844 FLJ10661 -0.72 -6.3 -0.49 4.69e-9 Mood instability; TGCT cis rs12477438 0.520 rs13023744 chr2:99738224 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.0 0.63 3.26e-15 Chronic sinus infection; TGCT cis rs587847 0.737 rs12148150 chr15:37657009 G/T cg00216138 chr15:37171175 LOC145845 0.31 4.49 0.37 1.59e-5 Intraocular pressure; TGCT cis rs9296092 0.538 rs3916674 chr6:33522975 C/T cg13560919 chr6:33536144 NA -0.2 -4.64 -0.38 8.68e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2404602 0.631 rs9646213 chr15:76807672 G/C cg26408565 chr15:76604113 ETFA -0.41 -5.22 -0.42 7.44e-7 Blood metabolite levels; TGCT cis rs4242434 0.699 rs878051 chr8:22483836 T/C cg03733263 chr8:22462867 KIAA1967 0.98 14.04 0.78 2.12e-27 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs36051895 0.695 rs12352214 chr9:5018041 G/A cg02405213 chr9:5042618 JAK2 -0.75 -9.96 -0.67 1.62e-17 Pediatric autoimmune diseases; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg27535305 chr1:53392650 SCP2 0.23 4.49 0.37 1.59e-5 Monocyte count; TGCT cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg05552183 chr6:42928497 GNMT 0.52 4.55 0.38 1.25e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs7267979 1.000 rs6083844 chr20:25386832 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467711 0.606 rs2073531 chr6:26375256 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs950169 0.887 rs35986397 chr15:84955107 G/A cg12863693 chr15:85201151 NMB 0.44 4.79 0.4 4.58e-6 Schizophrenia; TGCT cis rs6570726 0.764 rs9386125 chr6:145911677 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.28 0.64 7.13e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs780096 0.587 rs4665969 chr2:27574953 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.34 -4.43 -0.37 2.01e-5 Total body bone mineral density; TGCT cis rs7119038 0.818 rs56758835 chr11:118615340 G/A cg19308663 chr11:118741387 NA 0.29 5.39 0.44 3.41e-7 Sjögren's syndrome; TGCT cis rs3796352 1.000 rs113995589 chr3:53132372 A/T cg07884673 chr3:53033167 SFMBT1 0.54 5.76 0.46 6.2e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6088590 0.561 rs6087605 chr20:33180624 G/T cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs12460587 0.587 rs55899235 chr19:52603124 T/C cg13540795 chr19:52551618 ZNF432 -0.45 -4.8 -0.4 4.52e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs35146811 0.735 rs7811662 chr7:99792608 A/G cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.84 0.46 4.23e-8 Alzheimer's disease; TGCT cis rs9972944 0.651 rs8080916 chr17:63816368 G/C cg01592018 chr17:63456079 NA 0.25 4.43 0.37 2.01e-5 Total body bone mineral density; TGCT cis rs2702888 0.501 rs2741717 chr8:6747886 G/A cg26795848 chr8:6756730 NA -0.32 -6.39 -0.5 3.07e-9 Blood pressure; TGCT cis rs9527 0.545 rs7095304 chr10:104954795 G/A cg04362960 chr10:104952993 NT5C2 0.68 5.73 0.46 7.14e-8 Arsenic metabolism; TGCT cis rs748404 0.587 rs690276 chr15:43704558 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.56 0.38 1.21e-5 Lung cancer; TGCT cis rs7666738 0.830 rs10001702 chr4:99065160 T/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs916888 0.610 rs199536 chr17:44820425 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.58 -4.51 -0.38 1.51e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs11105298 0.891 rs10858869 chr12:89857611 C/T cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7447593 0.518 rs4074995 chr5:176797343 C/T cg17509989 chr5:176798049 RGS14 0.77 12.29 0.74 3.49e-23 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs1801251 1.000 rs7558609 chr2:233700379 C/T cg08000102 chr2:233561755 GIGYF2 0.64 6.54 0.51 1.44e-9 Coronary artery disease; TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg14159672 chr1:205819179 PM20D1 0.57 6.92 0.53 2.09e-10 Monocyte percentage of white cells; TGCT cis rs9682041 0.696 rs16855034 chr3:170097842 C/G cg11886554 chr3:170076028 SKIL 0.62 4.82 0.4 4.11e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs3806843 0.576 rs251370 chr5:140246287 C/T cg09824255 chr5:140014002 CD14 -0.26 -4.53 -0.38 1.35e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs6089829 0.962 rs4809462 chr20:61661560 A/G cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467773 0.933 rs35355150 chr6:26526039 G/A cg09904177 chr6:26538194 HMGN4 0.59 5.76 0.46 6.11e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs4440224 chr4:99044924 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2242116 0.900 rs4683300 chr3:46934292 C/A cg23352942 chr3:46931381 PTH1R -0.37 -5.81 -0.46 5.02e-8 Birth weight; TGCT cis rs950169 0.580 rs11634320 chr15:85172183 A/C cg17173187 chr15:85201210 NMB -0.62 -7.09 -0.54 8.99e-11 Schizophrenia; TGCT cis rs1878931 0.501 rs37800 chr16:3423648 T/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.75 -7.06 -0.54 1.05e-10 Body mass index (adult); TGCT cis rs7511006 1.000 rs7364173 chr22:50681029 C/T cg16473166 chr22:50639996 SELO -0.58 -5.81 -0.46 4.87e-8 Obesity-related traits; TGCT cis rs2204008 0.805 rs11169513 chr12:37988640 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs7772486 0.790 rs7742333 chr6:146159029 A/G cg23711669 chr6:146136114 FBXO30 -0.83 -8.94 -0.63 4.63e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs6570726 0.526 rs9376928 chr6:145724403 T/G cg23711669 chr6:146136114 FBXO30 -0.56 -4.99 -0.41 1.96e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6752107 0.901 rs34701569 chr2:234143048 C/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 5.01 0.41 1.79e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1153858 1.000 rs72623915 chr15:45647433 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs7523273 1.000 rs7523273 chr1:207977083 A/G cg22525895 chr1:207977042 MIR29B2 -0.49 -8.9 -0.62 5.71e-15 Schizophrenia; TGCT cis rs1555895 0.544 rs1555897 chr10:853674 A/C cg02193355 chr10:851439 NA 0.21 4.78 0.39 4.82e-6 Survival in rectal cancer; TGCT cis rs2204008 0.837 rs12370891 chr12:37984531 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg17554472 chr22:41940697 POLR3H -0.43 -4.56 -0.38 1.22e-5 Vitiligo; TGCT cis rs6912958 0.781 rs9450739 chr6:88268271 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs7267979 0.866 rs2424699 chr20:25257462 G/A cg16686733 chr20:25566563 NINL 0.62 6.15 0.48 9.65e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7014346 0.767 rs7837626 chr8:128423341 A/G cg04263511 chr8:128962092 PVT1 -0.31 -4.5 -0.37 1.54e-5 Colorectal cancer; TGCT cis rs1997103 1.000 rs6948112 chr7:55411302 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9916302 0.851 rs612209 chr17:37442713 G/C cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg24503407 chr1:205819492 PM20D1 0.56 7.64 0.57 5.08e-12 Menarche (age at onset); TGCT cis rs9733 0.565 rs11804276 chr1:150685761 T/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs910316 0.875 rs12588099 chr14:75594462 A/T cg08847533 chr14:75593920 NEK9 0.95 10.55 0.69 5.84e-19 Height; TGCT cis rs9611565 0.512 rs2899347 chr22:42158204 T/C cg06481639 chr22:41940642 POLR3H 0.69 6.02 0.48 1.83e-8 Vitiligo; TGCT cis rs10465746 0.967 rs12748268 chr1:84374438 T/C cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs76419734 0.558 rs10032269 chr4:106525703 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.81 4.6 0.38 1.02e-5 Post bronchodilator FEV1; TGCT cis rs1667284 0.967 rs1667281 chr18:29220756 C/G cg15259973 chr18:29078565 DSG2 0.53 5.19 0.42 8.27e-7 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs62380364 0.727 rs1671539 chr5:88168395 C/G cg22951263 chr5:87985283 NA 0.5 5.02 0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs2637266 1.000 rs17384253 chr10:78342391 A/G cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT cis rs4746818 0.892 rs10823298 chr10:70867083 T/C cg04149295 chr10:70884716 VPS26A 0.72 4.68 0.39 7.53e-6 Left atrial antero-posterior diameter; TGCT cis rs2197308 0.565 rs12809769 chr12:37909968 C/T cg13010199 chr12:38710504 ALG10B 0.67 5.38 0.44 3.57e-7 Morning vs. evening chronotype; TGCT cis rs7772486 0.754 rs6937661 chr6:146113299 T/C cg13319975 chr6:146136371 FBXO30 0.58 5.24 0.43 6.75e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg23982607 chr1:1823379 GNB1 -0.56 -8.49 -0.61 5.45e-14 Body mass index; TGCT cis rs734999 0.967 rs6671426 chr1:2504234 C/A cg18854424 chr1:2615690 NA 0.44 5.33 0.43 4.39e-7 Ulcerative colitis; TGCT cis rs1005277 0.522 rs289643 chr10:37941494 T/G cg25427524 chr10:38739819 LOC399744 -0.36 -7.05 -0.54 1.08e-10 Extrinsic epigenetic age acceleration; TGCT cis rs9911578 1.000 rs12952832 chr17:56906254 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.06 -0.48 1.53e-8 Intelligence (multi-trait analysis); TGCT cis rs838147 0.537 rs504963 chr19:49208865 G/A cg10667338 chr19:49617042 LIN7B -0.34 -4.65 -0.39 8.39e-6 Dietary macronutrient intake; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.12 -15.83 -0.82 1.5e-31 Prudent dietary pattern; TGCT cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg25767906 chr1:53392781 SCP2 0.5 5.73 0.46 7.21e-8 Monocyte count; TGCT cis rs240764 0.658 rs1039030 chr6:101198707 G/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs360798 0.532 rs11125942 chr2:62966758 T/C cg17519650 chr2:63277830 OTX1 -0.61 -5.51 -0.44 2e-7 Coronary artery disease; TGCT cis rs11264213 0.551 rs172081 chr1:36497498 T/G cg27506609 chr1:36549197 TEKT2 0.45 5.19 0.42 8.31e-7 Schizophrenia; TGCT cis rs6433857 0.657 rs6756509 chr2:181500273 T/C cg23363182 chr2:181467187 NA -0.33 -5.08 -0.42 1.33e-6 Body mass index; TGCT cis rs17270561 1.000 rs12211184 chr6:25823774 G/A cg16482183 chr6:26056742 HIST1H1C 0.79 5.25 0.43 6.49e-7 Iron status biomarkers; TGCT cis rs17221829 0.733 rs11018684 chr11:89364863 A/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs2836974 0.932 rs2836953 chr21:40617483 G/A cg11644478 chr21:40555479 PSMG1 1.0 10.69 0.69 2.7e-19 Cognitive function; TGCT cis rs3772130 0.775 rs6769102 chr3:121560722 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs7959452 0.605 rs12819406 chr12:69696400 G/T cg11871910 chr12:69753446 YEATS4 0.63 6.37 0.5 3.34e-9 Blood protein levels; TGCT cis rs11096990 0.964 rs6831700 chr4:39256964 G/T cg14806045 chr4:39367699 RFC1 -0.58 -4.55 -0.38 1.26e-5 Cognitive function; TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg08736216 chr1:53307985 ZYG11A -0.29 -6.02 -0.48 1.84e-8 Monocyte count; TGCT cis rs6461049 0.765 rs4719431 chr7:2140312 T/C cg22963979 chr7:1858916 MAD1L1 -0.44 -7.28 -0.55 3.29e-11 Schizophrenia; TGCT cis rs9303401 0.614 rs34843288 chr17:57103140 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.82 0.46 4.69e-8 Cognitive test performance; TGCT cis rs2070433 0.706 rs3788265 chr21:47833789 G/T cg04277056 chr21:48021941 S100B 0.35 5.02 0.41 1.75e-6 Lymphocyte counts; TGCT cis rs7267979 0.966 rs2482918 chr20:25412135 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7647973 0.626 rs1463728 chr3:49647404 T/A cg06212747 chr3:49208901 KLHDC8B 0.59 4.44 0.37 2e-5 Menarche (age at onset); TGCT cis rs910316 1.000 rs4322591 chr14:75600697 C/T cg11812906 chr14:75593930 NEK9 0.74 7.37 0.55 2.12e-11 Height; TGCT cis rs6840360 0.967 rs1511170 chr4:152701110 A/G cg22705602 chr4:152727874 NA -0.25 -4.63 -0.38 9.16e-6 Intelligence (multi-trait analysis); TGCT cis rs12643440 0.538 rs62296726 chr4:17143914 T/C cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs6490294 0.904 rs1016078 chr12:112410077 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs4862307 0.762 rs28584149 chr4:184996482 C/T cg06737308 chr4:185021514 ENPP6 0.32 4.58 0.38 1.1e-5 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs7772486 0.790 rs9376968 chr6:146180364 T/C cg23711669 chr6:146136114 FBXO30 0.91 10.41 0.68 1.3e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs61990749 0.597 rs4903643 chr14:78254791 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs11098499 0.863 rs2127823 chr4:120485670 G/T cg09307838 chr4:120376055 NA 0.74 7.34 0.55 2.49e-11 Corneal astigmatism; TGCT cis rs72949976 0.707 rs10932473 chr2:214039057 C/T cg08319019 chr2:214017104 IKZF2 -0.75 -6.35 -0.5 3.78e-9 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs9388451 0.868 rs10457467 chr6:126045148 T/A cg10911889 chr6:126070802 HEY2 0.5 4.91 0.4 2.75e-6 Brugada syndrome; TGCT cis rs10927875 0.541 rs1739844 chr1:16343322 T/C cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs288326 0.561 rs7595898 chr2:183819892 C/A cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs76419734 0.558 rs11730825 chr4:106527568 C/T cg24545054 chr4:106630052 GSTCD;INTS12 0.81 4.63 0.38 9.19e-6 Post bronchodilator FEV1; TGCT cis rs875971 0.540 rs736270 chr7:65428822 T/C cg00343986 chr7:65444356 GUSB 0.26 6.03 0.48 1.76e-8 Aortic root size; TGCT cis rs9807989 0.507 rs1035129 chr2:103019785 T/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs9467711 0.606 rs71557334 chr6:26365913 G/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7582180 0.585 rs12999151 chr2:100939333 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs9985766 0.793 rs10005992 chr4:150999112 A/T cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs739496 0.947 rs2238154 chr12:111882485 C/A cg10833066 chr12:111807467 FAM109A 0.36 5.51 0.44 2.01e-7 Platelet count; TGCT cis rs9916302 0.904 rs801420 chr17:37466103 C/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs7937682 0.924 rs10891286 chr11:111532691 C/G cg09085632 chr11:111637200 PPP2R1B -1.12 -11.81 -0.73 4.86e-22 Primary sclerosing cholangitis; TGCT cis rs3749237 0.595 rs7621003 chr3:49411404 T/C cg07636037 chr3:49044803 WDR6 0.64 6.04 0.48 1.63e-8 Resting heart rate; TGCT trans rs4650994 1.000 rs10798617 chr1:178515806 T/C cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.52e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.97 5.99 0.47 2.14e-8 Alzheimer's disease; TGCT trans rs877282 0.891 rs12357999 chr10:796468 A/C cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs8103278 0.507 rs2041975 chr19:46238555 T/C cg14061069 chr19:46274453 DMPK 0.63 10.97 0.7 5.44e-20 Coronary artery disease; TGCT cis rs1520333 0.958 rs13272546 chr8:79350425 G/A cg16589705 chr8:80226364 NA -0.3 -4.51 -0.38 1.47e-5 Multiple sclerosis; TGCT cis rs4478858 0.684 rs11579845 chr1:31736248 A/G cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs138249 0.898 rs138232 chr22:50559838 C/G cg24864161 chr22:50528282 MOV10L1 0.47 5.02 0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs6570726 0.967 rs6903252 chr6:145922777 A/G cg23711669 chr6:146136114 FBXO30 0.78 7.91 0.58 1.22e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs2445762 0.642 rs8025191 chr15:51623785 A/G cg00184732 chr15:51633821 GLDN 0.5 5.17 0.42 9.05e-7 Hormone measurements; TGCT cis rs62064224 0.818 rs11080181 chr17:30701210 C/T cg18200150 chr17:30822561 MYO1D 0.58 7.69 0.57 3.92e-12 Schizophrenia; TGCT cis rs3540 0.597 rs10152221 chr15:91047664 A/G cg22089800 chr15:90895588 ZNF774 -0.76 -7.77 -0.57 2.55e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs1799949 0.965 rs4792989 chr17:41437552 T/C cg10047753 chr17:41438598 NA 0.85 7.86 0.58 1.56e-12 Menopause (age at onset); TGCT trans rs7819412 0.745 rs4841498 chr8:10985432 C/T cg15556689 chr8:8085844 FLJ10661 -0.77 -7.39 -0.55 1.94e-11 Triglycerides; TGCT cis rs6951245 0.872 rs75280240 chr7:1058511 C/T cg03188948 chr7:1209495 NA 0.55 4.56 0.38 1.2e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3772130 0.962 rs4413346 chr3:121486310 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.53 4.83 0.4 3.97e-6 Cognitive performance; TGCT cis rs7584330 0.554 rs56881028 chr2:238446678 C/G cg08992911 chr2:238395768 MLPH 0.65 4.47 0.37 1.74e-5 Prostate cancer; TGCT cis rs9818758 0.505 rs67286839 chr3:49265744 C/T cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9560113 1.000 rs9560104 chr13:112174389 A/G cg14154082 chr13:112174009 NA 0.33 4.44 0.37 1.93e-5 Menarche (age at onset); TGCT cis rs7508 0.511 rs208056 chr8:17822884 C/T cg01800426 chr8:17659068 MTUS1 -0.67 -5.05 -0.41 1.53e-6 Atrial fibrillation; TGCT cis rs7044106 0.762 rs10760110 chr9:123412563 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.6 -6.29 -0.49 4.9e-9 Hip circumference adjusted for BMI; TGCT cis rs7772486 0.875 rs2224120 chr6:146343280 A/C cg23711669 chr6:146136114 FBXO30 0.88 9.67 0.66 7.78e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs8078723 0.866 rs11078934 chr17:38189793 C/T cg17467752 chr17:38218738 THRA 0.69 6.8 0.52 3.94e-10 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs9325144 0.647 rs7487395 chr12:38865660 C/A cg10518543 chr12:38710700 ALG10B -0.48 -4.44 -0.37 1.99e-5 Morning vs. evening chronotype; TGCT cis rs7666738 0.830 rs13139078 chr4:99020774 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11650776 1 rs11650776 chr17:37641402 G/A cg15445000 chr17:37608096 MED1 0.31 4.57 0.38 1.17e-5 Lung function (FEV1); TGCT cis rs7208859 0.623 rs11651858 chr17:29170718 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9902453 0.791 rs55655651 chr17:28244286 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.28 0.55 3.32e-11 Coffee consumption (cups per day); TGCT cis rs7226408 0.894 rs72885207 chr18:34397344 G/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs4268898 0.722 rs6723257 chr2:24391129 A/G cg02683114 chr2:24398427 C2orf84 0.19 4.57 0.38 1.14e-5 Asthma; TGCT cis rs6988636 0.534 rs57815619 chr8:124096724 A/G cg27053337 chr8:124217698 FAM83A 0.54 4.68 0.39 7.34e-6 Urinary uromodulin levels; TGCT cis rs3026101 0.671 rs11868032 chr17:5283617 A/T cg25236894 chr17:5323110 RPAIN;NUP88 0.46 4.53 0.38 1.39e-5 Body mass index; TGCT cis rs2013441 1.000 rs17686798 chr17:20029170 A/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.72 -0.39 6.21e-6 Obesity-related traits; TGCT cis rs8103278 0.507 rs8112282 chr19:46265029 C/T cg14061069 chr19:46274453 DMPK 0.63 10.79 0.7 1.51e-19 Coronary artery disease; TGCT trans rs797680 0.856 rs4847408 chr1:93791437 C/G cg27528825 chr2:159282178 CCDC148 0.33 6.67 0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10465746 0.780 rs1570691 chr1:84370393 A/C cg10977910 chr1:84465055 TTLL7 0.66 6.65 0.51 8.38e-10 Obesity-related traits; TGCT cis rs10419226 0.604 rs12976741 chr19:18767477 G/A cg14292368 chr19:18793705 CRTC1 -0.49 -5.42 -0.44 2.98e-7 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9611565 0.571 rs7364123 chr22:42216326 A/G cg06634786 chr22:41940651 POLR3H -0.76 -6.92 -0.53 2.2e-10 Vitiligo; TGCT cis rs1971762 0.563 rs10747678 chr12:54077687 A/C cg16917193 chr12:54089295 NA -1.34 -17.66 -0.85 1.17e-35 Height; TGCT trans rs10506458 0.915 rs60094497 chr12:63394838 T/G cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs12541335 0.639 rs11135995 chr8:22200148 C/T cg27266060 chr8:22091797 NA -0.24 -4.55 -0.38 1.24e-5 Hypertriglyceridemia; TGCT cis rs9894429 0.646 rs9905639 chr17:79614154 A/G cg18240062 chr17:79603768 NPLOC4 0.56 4.93 0.4 2.58e-6 Eye color traits; TGCT cis rs9330316 0.632 rs28615410 chr2:110334358 C/A cg25199208 chr2:109402912 CCDC138 -0.42 -4.56 -0.38 1.19e-5 Schizophrenia; TGCT cis rs7772486 0.754 rs2328709 chr6:146106819 A/G cg23711669 chr6:146136114 FBXO30 -0.93 -10.29 -0.68 2.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467711 0.606 rs2076030 chr6:26426856 G/A cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6570726 0.526 rs4896805 chr6:145735429 C/A cg23711669 chr6:146136114 FBXO30 -0.55 -4.82 -0.4 4.15e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9291683 0.610 rs993172 chr4:10324361 G/T cg11266682 chr4:10021025 SLC2A9 0.51 5.98 0.47 2.2e-8 Bone mineral density; TGCT cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs700590 0.603 rs304151 chr5:88125853 G/T cg22951263 chr5:87985283 NA -0.63 -5.75 -0.46 6.52e-8 Educational attainment (years of education); TGCT cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg00149659 chr3:10157352 C3orf10 0.94 6.0 0.47 2e-8 Alzheimer's disease; TGCT cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs13217239 0.621 rs12527231 chr6:27001288 G/A cg15659132 chr6:26577336 NA 0.54 5.44 0.44 2.78e-7 Schizophrenia; TGCT cis rs9926296 0.712 rs258332 chr16:89727683 G/A cg04287289 chr16:89883240 FANCA -0.54 -5.01 -0.41 1.82e-6 Vitiligo; TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs3733585 0.725 rs10939636 chr4:9972640 T/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.72 -0.52 5.74e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12541335 0.639 rs11135995 chr8:22200148 C/T cg18135555 chr8:22132992 PIWIL2 -0.29 -6.06 -0.48 1.48e-8 Hypertriglyceridemia; TGCT cis rs4566357 1.000 rs7577005 chr2:227921573 A/G cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg16325326 chr1:53192061 ZYG11B -0.73 -8.95 -0.63 4.41e-15 Monocyte count; TGCT cis rs7666738 0.791 rs2081621 chr4:98926753 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4727027 0.704 rs12704073 chr7:148905067 G/A cg23583168 chr7:148888333 NA -0.83 -10.97 -0.7 5.54e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4746818 0.818 rs7076011 chr10:70900430 T/C cg04149295 chr10:70884716 VPS26A 0.79 5.4 0.44 3.22e-7 Left atrial antero-posterior diameter; TGCT cis rs3809566 0.676 rs11071719 chr15:63329875 C/A cg00520135 chr15:63333846 TPM1 -0.42 -5.16 -0.42 9.55e-7 Platelet count; TGCT cis rs796364 0.806 rs76568708 chr2:200929531 C/T cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs7474896 0.515 rs2738208 chr10:38306128 A/G cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs889312 0.500 rs1867731 chr5:56132115 C/G cg24531977 chr5:56204891 C5orf35 -0.53 -5.5 -0.44 2.07e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs7412746 0.566 rs2864871 chr1:150766964 T/C cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs7829975 0.688 rs13270194 chr8:8378102 T/C cg08975724 chr8:8085496 FLJ10661 0.63 5.98 0.47 2.25e-8 Mood instability; TGCT cis rs6570726 0.875 rs368744 chr6:145812622 A/G cg23711669 chr6:146136114 FBXO30 0.73 6.85 0.52 3e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs901683 0.702 rs78757497 chr10:46161918 T/C cg03466342 chr12:52753899 KRT85 -0.6 -7.26 -0.55 3.79e-11 Red blood cell traits;Mean corpuscular volume; TGCT cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg27211696 chr2:191398769 TMEM194B -0.27 -5.07 -0.41 1.42e-6 Pulse pressure; TGCT cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg06481639 chr22:41940642 POLR3H -0.61 -5.49 -0.44 2.17e-7 Vitiligo; TGCT cis rs9419702 0.614 rs4897816 chr10:133533646 G/A cg20568497 chr10:133558893 NA 0.45 4.73 0.39 6e-6 Survival in rectal cancer; TGCT cis rs10751667 0.666 rs6597962 chr11:976351 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.11 -0.59 4.17e-13 Alzheimer's disease (late onset); TGCT cis rs151997 0.671 rs27281 chr5:50200764 C/T cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs9831754 0.756 rs6548554 chr3:78423185 C/T cg06138941 chr3:78371609 NA -0.39 -4.43 -0.37 2.01e-5 Calcium levels; TGCT cis rs13191362 0.872 rs13194619 chr6:163203657 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.11 8.17 0.59 2.98e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs950169 0.922 rs62028133 chr15:84919375 A/C cg12863693 chr15:85201151 NMB 0.41 4.5 0.38 1.51e-5 Schizophrenia; TGCT trans rs1814175 0.546 rs1614397 chr11:49913384 G/C cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs3741404 0.791 rs11603192 chr11:63927695 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.87 9.54 0.65 1.61e-16 Platelet count; TGCT cis rs7772486 0.686 rs4896833 chr6:145965673 T/G cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.23e-9 Blood metabolite levels; TGCT cis rs6988636 1.000 rs28542077 chr8:124190896 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs11122272 0.735 rs2749714 chr1:231538634 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs9796 0.689 rs692153 chr15:41452681 C/T cg18705301 chr15:41695430 NDUFAF1 -0.5 -6.75 -0.52 5.02e-10 Menopause (age at onset); TGCT cis rs175714 0.845 rs175706 chr14:75976200 G/A cg01624173 chr14:75981868 NA 0.4 7.44 0.56 1.47e-11 Lymphocyte counts; TGCT cis rs2859741 1.000 rs4653239 chr1:37509872 C/G cg09363841 chr1:37513479 NA 0.19 4.49 0.37 1.63e-5 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs853679 0.517 rs9380049 chr6:28048535 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs2576037 0.623 rs2576040 chr18:44582027 A/G cg23302884 chr18:44338147 ST8SIA5 0.39 4.52 0.38 1.44e-5 Personality dimensions; TGCT trans rs7824557 0.527 rs2736305 chr8:11237773 T/C cg15556689 chr8:8085844 FLJ10661 -0.75 -6.65 -0.51 8.2e-10 Retinal vascular caliber; TGCT cis rs826838 0.616 rs11182893 chr12:38627715 C/G cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs13082711 0.522 rs653076 chr3:27343691 T/C cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs477895 0.713 rs7952318 chr11:63961242 G/A cg04317338 chr11:64019027 PLCB3 0.79 6.65 0.51 8.44e-10 Mean platelet volume; TGCT cis rs9911578 0.874 rs302865 chr17:56756977 A/G cg12560992 chr17:57184187 TRIM37 0.71 8.43 0.6 7.36e-14 Intelligence (multi-trait analysis); TGCT cis rs4595586 0.870 rs10444553 chr12:39294076 C/G cg10518543 chr12:38710700 ALG10B 0.46 4.54 0.38 1.29e-5 Morning vs. evening chronotype; TGCT cis rs9357506 1.000 rs12055643 chr6:46306348 C/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs75059851 0.756 rs73036087 chr11:133842361 G/A cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs597539 0.652 rs496616 chr11:68672800 G/C cg21862992 chr11:68658383 NA 0.46 6.54 0.51 1.45e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12497850 0.931 rs3774628 chr3:48801840 C/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.73 0.46 7.23e-8 Parkinson's disease; TGCT cis rs826838 1.000 rs826889 chr12:39101076 G/A cg13010199 chr12:38710504 ALG10B -0.61 -4.98 -0.41 2.06e-6 Heart rate; TGCT cis rs12643440 0.538 rs4299576 chr4:17140108 G/A cg22650099 chr4:17144496 NA -0.45 -4.65 -0.39 8.28e-6 Metabolite levels (Pyroglutamine); TGCT cis rs1857353 1.000 rs4949854 chr1:75912119 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs11098499 0.821 rs28665282 chr4:120384186 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs6582630 0.555 rs10880520 chr12:38464111 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs67460515 0.892 rs1382429 chr3:161015153 T/C cg03342759 chr3:160939853 NMD3 -0.51 -5.42 -0.44 2.98e-7 Parkinson's disease; TGCT cis rs7786877 0.508 rs11765509 chr7:100310990 T/G cg20848291 chr7:100343083 ZAN -0.52 -4.51 -0.38 1.46e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7027203 0.557 rs9299411 chr9:96523104 C/A cg13679303 chr9:96623674 NA -0.53 -7.48 -0.56 1.18e-11 DNA methylation (variation); TGCT cis rs2115536 0.967 rs4778734 chr15:80210851 A/G cg00225070 chr15:80189496 MTHFS 0.58 5.03 0.41 1.66e-6 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4820539 1.000 rs6003518 chr22:23471533 C/T cg14186256 chr22:23484241 RTDR1 0.99 12.58 0.75 6.81e-24 Bone mineral density; TGCT cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg22535103 chr8:58192502 C8orf71 -0.4 -5.06 -0.41 1.44e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg24829409 chr8:58192753 C8orf71 -0.55 -5.17 -0.42 9.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.754 rs6922507 chr6:146250155 A/T cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12510870 0.599 rs12503916 chr4:74451259 C/T cg05868023 chr4:75230803 EREG -0.54 -4.75 -0.39 5.61e-6 Iris color (b* coordinate); TGCT cis rs362272 0.545 rs2749785 chr4:3325179 G/C cg06533319 chr4:3265114 C4orf44 -0.28 -5.69 -0.45 8.71e-8 Serum sulfate level; TGCT cis rs875971 0.862 rs6460279 chr7:65662761 T/C cg11764359 chr7:65958608 NA -0.53 -4.7 -0.39 6.81e-6 Aortic root size; TGCT cis rs597539 0.652 rs546382 chr11:68704264 C/T cg04772025 chr11:68637568 NA 0.62 6.89 0.53 2.52e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7412746 0.611 rs2864873 chr1:150814174 A/G cg04414720 chr1:150670196 GOLPH3L 0.41 5.14 0.42 1.06e-6 Melanoma; TGCT trans rs916888 0.779 rs199528 chr17:44843136 C/T cg10053473 chr17:62856997 LRRC37A3 -0.45 -6.78 -0.52 4.41e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs854765 0.583 rs11650649 chr17:17790319 C/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.98 -0.58 8.43e-13 Total body bone mineral density; TGCT cis rs1005277 0.505 rs200936 chr10:38134935 T/C cg25427524 chr10:38739819 LOC399744 -0.37 -7.41 -0.55 1.75e-11 Extrinsic epigenetic age acceleration; TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg25767906 chr1:53392781 SCP2 -0.63 -7.64 -0.57 5e-12 Monocyte count; TGCT cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg16423285 chr20:60520624 NA -0.61 -6.89 -0.53 2.44e-10 Body mass index; TGCT cis rs59107033 0.607 rs55925662 chr3:123118699 A/G cg04890266 chr3:123102914 ADCY5 -0.39 -5.49 -0.44 2.12e-7 Lymphocyte counts; TGCT cis rs1008375 0.797 rs6843530 chr4:17593605 G/T cg10189774 chr4:17578691 LAP3 0.71 6.05 0.48 1.59e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs79349575 0.749 rs8182364 chr17:47018025 A/G cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs12369179 0.737 rs116896792 chr12:122948907 T/C cg18578876 chr12:123200353 GPR109B -0.44 -4.5 -0.37 1.57e-5 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; TGCT cis rs3806843 0.583 rs408652 chr5:140330013 T/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.73e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs71435601 0.574 rs1652421 chr2:21383848 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs67311347 0.549 rs60249586 chr3:40246659 G/A cg13683864 chr3:40499215 RPL14 -0.75 -6.94 -0.53 1.93e-10 Renal cell carcinoma; TGCT cis rs9291683 0.517 rs11736479 chr4:10017387 G/C cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Bone mineral density; TGCT cis rs617219 0.710 rs10054122 chr5:78581371 A/T cg23987322 chr5:78407566 BHMT -0.37 -5.01 -0.41 1.81e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2050392 0.687 rs608693 chr10:30734971 G/A cg18806716 chr10:30721971 MAP3K8 -0.52 -5.91 -0.47 3.06e-8 Inflammatory bowel disease; TGCT cis rs9522267 0.535 rs9515453 chr13:112234612 T/C cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs6860806 0.507 rs272880 chr5:131670178 C/T cg24060327 chr5:131705240 SLC22A5 -0.75 -8.11 -0.59 4.12e-13 Breast cancer; TGCT cis rs10197940 0.578 rs2432946 chr2:152306897 G/T cg19508488 chr2:152266495 RIF1 -0.56 -4.68 -0.39 7.3e-6 Lung cancer; TGCT cis rs11785400 0.793 rs4430071 chr8:143737680 T/C cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs11039216 1 rs11039216 chr11:47406592 C/T cg20307385 chr11:47447363 PSMC3 0.57 5.59 0.45 1.39e-7 Neuroticism; TGCT cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.49 -0.61 5.27e-14 Platelet count; TGCT cis rs6586163 0.509 rs2031610 chr10:90754487 T/C cg03111039 chr10:90751583 FAS;ACTA2 0.6 7.77 0.57 2.59e-12 Chronic lymphocytic leukemia; TGCT cis rs2463822 1.000 rs2246920 chr11:62104937 T/G cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs5769707 0.904 rs7288869 chr22:50015327 C/T cg10356904 chr22:49881777 NA -0.23 -4.54 -0.38 1.3e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs3820068 0.603 rs67349836 chr1:15966176 T/C cg05660106 chr1:15850417 CASP9 0.79 7.94 0.58 1.04e-12 Systolic blood pressure; TGCT cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg18876405 chr7:65276391 NA 0.38 5.89 0.47 3.32e-8 Aortic root size; TGCT cis rs7267979 1.000 rs1077889 chr20:25267893 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3847687 1.000 rs11061291 chr12:131518875 C/T cg13586425 chr12:131519906 GPR133 -0.31 -4.67 -0.39 7.75e-6 Longevity; TGCT cis rs6430585 0.941 rs7589832 chr2:136504101 A/C cg07169764 chr2:136633963 MCM6 0.91 8.26 0.6 1.86e-13 Corneal structure; TGCT cis rs7666738 0.830 rs34070283 chr4:98893027 A/T cg17366294 chr4:99064904 C4orf37 0.68 6.87 0.53 2.72e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.652 rs602805 chr11:68662076 A/T cg04772025 chr11:68637568 NA 0.6 6.77 0.52 4.63e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1215050 0.547 rs10008398 chr4:98607327 A/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3087591 0.919 rs2012581 chr17:29560800 A/G cg24425628 chr17:29625626 OMG;NF1 -0.49 -7.65 -0.57 4.82e-12 Hip circumference; TGCT cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 2.93e-27 Menopause (age at onset); TGCT cis rs9291683 0.507 rs3796837 chr4:10011321 C/G cg11266682 chr4:10021025 SLC2A9 0.65 8.48 0.61 5.78e-14 Bone mineral density; TGCT cis rs858239 0.896 rs1637192 chr7:23260514 G/A cg05602783 chr7:23145260 KLHL7 -0.66 -5.55 -0.45 1.68e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1577917 0.785 rs1885607 chr6:86394905 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.64 5.85 0.47 4.09e-8 Response to antipsychotic treatment; TGCT cis rs6424115 0.830 rs1105 chr1:24200800 T/C cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs7829975 0.658 rs2409096 chr8:8692477 T/C cg15556689 chr8:8085844 FLJ10661 0.67 5.98 0.47 2.2e-8 Mood instability; TGCT cis rs7824557 0.591 rs2060457 chr8:11213250 C/T cg21775007 chr8:11205619 TDH 0.68 6.46 0.5 2.16e-9 Retinal vascular caliber; TGCT cis rs9926296 0.632 rs4785717 chr16:89801133 A/G cg03388025 chr16:89894329 SPIRE2 0.32 4.69 0.39 7.03e-6 Vitiligo; TGCT cis rs9915657 0.773 rs9916815 chr17:70105651 A/G cg06234051 chr17:70120541 SOX9 -0.26 -5.37 -0.43 3.78e-7 Thyroid hormone levels; TGCT cis rs7824557 0.778 rs6601572 chr8:11093337 C/G cg21775007 chr8:11205619 TDH -0.5 -4.55 -0.38 1.27e-5 Retinal vascular caliber; TGCT cis rs2204008 0.837 rs11168334 chr12:37961768 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.94 0.41 2.49e-6 Bladder cancer; TGCT cis rs10276303 0.584 rs2614950 chr7:3581391 A/G cg05061754 chr7:4254313 SDK1 0.21 4.49 0.37 1.6e-5 Dupuytren's disease; TGCT cis rs4824093 0.610 rs7410534 chr22:50289925 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.12 -6.78 -0.52 4.3e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg20637647 chr7:64974828 NA -0.88 -5.12 -0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs11690462 0.926 rs11689086 chr2:26549127 C/T cg04726446 chr2:26624865 C2orf39 0.43 4.61 0.38 9.87e-6 Coronary artery disease; TGCT cis rs1723838 0.826 rs1670560 chr11:73600167 G/A cg18195628 chr11:73498948 MRPL48 0.93 4.55 0.38 1.28e-5 Obesity-related traits; TGCT cis rs4851254 0.920 rs11686599 chr2:100753475 A/G cg04109781 chr2:100722022 AFF3 0.45 4.8 0.4 4.51e-6 Intelligence (multi-trait analysis); TGCT cis rs2797160 0.651 rs6569436 chr6:126032104 A/G cg05901451 chr6:126070800 HEY2 0.71 6.52 0.51 1.57e-9 Endometrial cancer; TGCT cis rs11671005 0.735 rs11667723 chr19:58927489 A/G cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT cis rs7666738 0.830 rs62321598 chr4:99014237 C/T cg18180107 chr4:99064573 C4orf37 0.56 5.28 0.43 5.54e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs1005277 0.579 rs2474599 chr10:38438939 A/G cg27523141 chr10:43048294 ZNF37B 0.74 8.61 0.61 2.7e-14 Extrinsic epigenetic age acceleration; TGCT cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg04944784 chr2:26401820 FAM59B -0.73 -5.95 -0.47 2.61e-8 Gut microbiome composition (summer); TGCT cis rs6674176 0.628 rs4660758 chr1:44424879 A/C cg13606994 chr1:44402422 ARTN -0.46 -4.84 -0.4 3.73e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg18402987 chr7:1209562 NA 0.74 6.42 0.5 2.6e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg10117171 chr1:25599238 RHD -0.36 -5.69 -0.45 8.8e-8 Erythrocyte sedimentation rate; TGCT cis rs11030122 0.673 rs4910590 chr11:4018619 C/T cg18678763 chr11:4115507 RRM1 -0.48 -5.88 -0.47 3.54e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs739496 0.843 rs610769 chr12:111999570 G/A cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs17767294 0.708 rs72848770 chr6:27919149 A/G cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs7027203 0.964 rs7853688 chr9:96523254 C/A cg13679303 chr9:96623674 NA 0.64 9.79 0.66 4.09e-17 DNA methylation (variation); TGCT cis rs9467711 0.516 rs1165168 chr6:25859508 A/C cg03517284 chr6:25882590 NA -0.73 -4.85 -0.4 3.62e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9467773 0.935 rs4573 chr6:26546808 A/G cg02458000 chr6:26745757 NA 0.54 5.37 0.43 3.68e-7 Intelligence (multi-trait analysis); TGCT cis rs45509595 0.659 rs390764 chr6:27782535 C/T cg10876282 chr6:28092338 ZSCAN16 0.78 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs7208859 0.623 rs79607958 chr17:28934548 T/G cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7267979 0.844 rs869358 chr20:25374674 A/G cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs137699 1.000 rs137699 chr22:39748854 A/G cg05872129 chr22:39784769 NA -0.56 -4.65 -0.39 8.39e-6 IgG glycosylation; TGCT cis rs149613931 1 rs149613931 chr10:103550281 G/T cg22630918 chr10:102748988 C10orf2 0.44 4.91 0.4 2.83e-6 Educational attainment (years of education); TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg03407747 chr17:6899364 ALOX12 0.53 5.71 0.46 7.9e-8 Tonsillectomy; TGCT cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg15320075 chr8:145703422 NA -0.71 -7.16 -0.54 6.3e-11 Age at first birth; TGCT cis rs17221829 0.965 rs4553368 chr11:89459742 T/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.76 -0.39 5.25e-6 Anxiety in major depressive disorder; TGCT cis rs6964587 0.839 rs6952459 chr7:91435820 T/A cg17063962 chr7:91808500 NA 0.82 8.45 0.6 6.54e-14 Breast cancer; TGCT cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg25703541 chr22:24373054 LOC391322 -0.82 -8.68 -0.61 1.87e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7552404 1.000 rs11161510 chr1:76210289 A/G cg03433033 chr1:76189801 ACADM -0.83 -9.84 -0.66 3.03e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2147959 0.825 rs12746910 chr1:228658133 G/A cg22700015 chr1:228743131 NA 0.57 4.54 0.38 1.31e-5 Adult asthma; TGCT cis rs7729723 0.591 rs6870458 chr5:137818916 G/T cg19169342 chr5:137827400 NA 0.35 5.0 0.41 1.91e-6 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg12386194 chr3:101231763 SENP7 0.56 5.44 0.44 2.78e-7 Colorectal cancer; TGCT cis rs11718455 0.582 rs6763436 chr3:43913653 A/G cg08738300 chr3:44038990 NA -0.82 -5.49 -0.44 2.16e-7 Coronary artery disease; TGCT cis rs4851254 0.584 rs56935201 chr2:100637788 G/A cg22139774 chr2:100720529 AFF3 -0.45 -4.9 -0.4 2.94e-6 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.559 rs10953531 chr7:106827867 A/G cg02696742 chr7:106810147 HBP1 0.74 6.14 0.48 1.05e-8 Coronary artery disease; TGCT cis rs10875746 0.859 rs4760695 chr12:48591848 A/G cg20731937 chr12:48336164 NA 0.63 5.05 0.41 1.51e-6 Longevity (90 years and older); TGCT cis rs7172809 0.599 rs10519158 chr15:77412457 G/C cg22256960 chr15:77711686 NA -0.47 -4.51 -0.38 1.51e-5 Glucose homeostasis traits; TGCT cis rs11578119 0.898 rs7519067 chr1:170395209 T/C cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.67e-8 Male-pattern baldness; TGCT cis rs10504229 0.953 rs114806125 chr8:58182416 C/T cg22535103 chr8:58192502 C8orf71 -0.37 -4.73 -0.39 6.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg07167872 chr1:205819463 PM20D1 0.55 6.95 0.53 1.81e-10 Menarche (age at onset); TGCT cis rs1483890 0.605 rs1483889 chr3:69413324 A/G cg22125112 chr3:69402811 FRMD4B 0.28 4.75 0.39 5.63e-6 Resting heart rate; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg21672276 chr3:44754072 ZNF502 -0.46 -5.2 -0.42 8.08e-7 Depressive symptoms; TGCT cis rs2888674 0.933 rs10267707 chr7:150510973 C/G cg10409299 chr7:150498843 TMEM176B;TMEM176A 0.28 4.8 0.4 4.47e-6 Forced expiratory volume in 1 second (occupational environmental exposures interaction); TGCT cis rs6952808 0.595 rs3778984 chr7:2166514 T/C cg22963979 chr7:1858916 MAD1L1 -0.4 -6.38 -0.5 3.12e-9 Bipolar disorder and schizophrenia; TGCT cis rs769267 0.930 rs3752151 chr19:19616026 T/C cg08509172 chr19:19383838 TM6SF2 -0.34 -4.52 -0.38 1.4e-5 Tonsillectomy; TGCT cis rs7552404 0.731 rs61770552 chr1:76373050 T/C cg22875332 chr1:76189707 ACADM 0.69 6.67 0.51 7.46e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10089 1.000 rs4836368 chr5:127486330 T/A cg19767477 chr5:127420684 SLC12A2 -0.43 -4.52 -0.38 1.45e-5 Ileal carcinoids; TGCT cis rs4478858 0.684 rs4949372 chr1:31738857 G/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs13190036 1.000 rs35535623 chr5:176629296 A/G cg18465082 chr5:176734745 MXD3 0.32 4.44 0.37 1.95e-5 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs60843830 0.928 rs55742348 chr2:217563 T/A cg25945732 chr2:264204 ACP1;SH3YL1 0.77 7.33 0.55 2.57e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9303401 0.625 rs10515159 chr17:56802693 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs2847281 0.764 rs2847257 chr18:12776050 G/A cg23598886 chr18:12777645 NA 0.36 4.54 0.38 1.3e-5 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs904251 0.861 rs914349 chr6:37484715 A/C cg25019722 chr6:37503610 NA -0.48 -6.8 -0.52 3.98e-10 Cognitive performance; TGCT cis rs77972916 0.505 rs1322 chr2:43521167 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -5.72 -0.46 7.48e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs4820539 1.000 rs5759598 chr22:23480962 T/G cg21100191 chr22:23484243 RTDR1 0.9 10.72 0.69 2.2e-19 Bone mineral density; TGCT cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg08439880 chr3:133502540 NA 0.35 7.0 0.53 1.43e-10 Iron status biomarkers; TGCT cis rs11190604 1.000 rs1800662 chr10:102289078 C/A cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs700651 0.789 rs10184395 chr2:198894285 G/A cg00792783 chr2:198669748 PLCL1 0.59 5.34 0.43 4.33e-7 Intracranial aneurysm; TGCT cis rs6988636 1.000 rs6983795 chr8:124185296 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs67311347 1.000 rs4571217 chr3:40521973 A/G cg13683864 chr3:40499215 RPL14 -1.21 -13.32 -0.77 1.11e-25 Renal cell carcinoma; TGCT cis rs763014 1.000 rs8054842 chr16:672799 T/C cg27436995 chr16:743998 FBXL16 -0.48 -5.23 -0.43 6.97e-7 Height; TGCT trans rs1814175 0.817 rs12287396 chr11:49819798 G/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg09177884 chr7:1199841 ZFAND2A -0.49 -4.79 -0.39 4.76e-6 Longevity;Endometriosis; TGCT cis rs4319547 0.615 rs2341439 chr12:122848096 C/G cg05707623 chr12:122985044 ZCCHC8 -0.57 -4.62 -0.38 9.55e-6 Body mass index; TGCT cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg11890956 chr21:40555474 PSMG1 -0.79 -7.82 -0.57 2e-12 Cognitive function; TGCT cis rs2445762 0.518 rs8043240 chr15:51635565 C/T cg00184732 chr15:51633821 GLDN 0.46 5.17 0.42 8.99e-7 Hormone measurements; TGCT trans rs1814175 0.935 rs10839329 chr11:49694206 G/A cg03929089 chr4:120376271 NA -0.63 -7.0 -0.53 1.41e-10 Height; TGCT cis rs12497850 0.897 rs7373778 chr3:48836392 C/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs617219 0.551 rs2131978 chr5:78613986 G/A cg23514016 chr5:78407564 BHMT -0.31 -4.77 -0.39 5.08e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4455778 0.580 rs9942682 chr7:49077999 G/C cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.07e-9 Lung cancer in never smokers; TGCT cis rs11822910 1.000 rs4477456 chr11:57197781 G/A cg00522883 chr11:57194120 SLC43A3 0.36 4.61 0.38 9.93e-6 Platelet distribution width; TGCT cis rs16958440 0.867 rs2117373 chr18:44671834 C/T cg17192377 chr18:44677553 HDHD2 0.54 4.51 0.38 1.46e-5 Sitting height ratio; TGCT cis rs9913156 0.793 rs72835644 chr17:4573667 G/A cg00122941 chr17:4613640 ARRB2 0.89 7.52 0.56 9.78e-12 Lymphocyte counts; TGCT cis rs903263 0.601 rs12404263 chr1:84551736 G/A cg09664975 chr1:84543551 PRKACB 0.5 4.86 0.4 3.47e-6 Breast cancer (male); TGCT cis rs9926296 0.585 rs6500450 chr16:89858024 A/G cg04287289 chr16:89883240 FANCA 0.94 12.2 0.74 5.63e-23 Vitiligo; TGCT cis rs12477438 0.765 rs6722164 chr2:99561527 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.55 -4.62 -0.38 9.65e-6 Chronic sinus infection; TGCT trans rs8073060 0.586 rs72828038 chr17:33893908 C/A cg19694781 chr19:47549865 TMEM160 0.59 12.81 0.75 1.88e-24 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.918 rs2281333 chr22:41749630 T/C cg06481639 chr22:41940642 POLR3H -0.56 -4.92 -0.4 2.64e-6 Vitiligo; TGCT cis rs2439831 0.681 rs28578454 chr15:43603032 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.08 7.95 0.58 9.61e-13 Lung cancer in ever smokers; TGCT cis rs3087591 0.960 rs2018634 chr17:29560678 A/C cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.49 -0.56 1.11e-11 Hip circumference; TGCT cis rs10927875 0.518 rs1763604 chr1:16339772 C/G cg21385522 chr1:16154831 NA 0.47 4.87 0.4 3.31e-6 Dilated cardiomyopathy; TGCT cis rs10875746 0.537 rs4760625 chr12:48673743 A/T cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg12419862 chr22:24373484 LOC391322 -0.83 -8.85 -0.62 7.63e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6545883 0.894 rs12997538 chr2:61564249 A/C cg15711740 chr2:61764176 XPO1 0.52 4.54 0.38 1.34e-5 Tuberculosis; TGCT cis rs2115630 1.000 rs11854313 chr15:85304048 G/C cg11189052 chr15:85197271 WDR73 -0.63 -6.04 -0.48 1.67e-8 P wave terminal force; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg04234412 chr22:24373322 LOC391322 -0.92 -11.98 -0.73 1.94e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs1005277 0.579 rs2023351 chr10:38378814 A/G cg17830980 chr10:43048298 ZNF37B -0.87 -11.11 -0.71 2.53e-20 Extrinsic epigenetic age acceleration; TGCT cis rs796364 0.577 rs7574287 chr2:200680999 C/T cg17644776 chr2:200775616 C2orf69 0.34 4.84 0.4 3.76e-6 Schizophrenia; TGCT cis rs9357506 1.000 rs9357505 chr6:46316191 T/A cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs7000551 0.700 rs7431 chr8:22398462 G/A cg12081754 chr8:22256438 SLC39A14 0.27 4.5 0.37 1.54e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs56114371 0.777 rs200483 chr6:27774824 C/T cg08798685 chr6:27730294 NA -0.32 -4.44 -0.37 1.95e-5 Breast cancer; TGCT cis rs12188164 1.000 rs72717410 chr5:428785 A/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.41 -4.75 -0.39 5.43e-6 Cystic fibrosis severity; TGCT cis rs981844 0.712 rs1456398 chr4:154738266 G/A cg14289246 chr4:154710475 SFRP2 -1.0 -9.32 -0.64 5.46e-16 Response to statins (LDL cholesterol change); TGCT cis rs78707713 0.511 rs28697194 chr10:71215483 T/C cg14388049 chr10:71211838 TSPAN15 -0.39 -4.5 -0.37 1.55e-5 Venous thromboembolism; TGCT cis rs12681287 0.752 rs1080170 chr8:87310108 C/T cg27223183 chr8:87520930 FAM82B -0.85 -6.4 -0.5 2.9e-9 Caudate activity during reward; TGCT cis rs4285028 0.747 rs77790376 chr3:121492211 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -1.03 -8.75 -0.62 1.26e-14 Multiple sclerosis; TGCT cis rs2458413 0.669 rs1812214 chr8:105344070 A/G cg23108931 chr8:105342351 NA -0.35 -6.19 -0.49 7.93e-9 Paget's disease; TGCT trans rs7726839 0.540 rs11750321 chr5:599196 C/T cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs7267979 1.000 rs2257991 chr20:25270339 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12549902 0.966 rs17659386 chr8:41513531 T/C cg21772509 chr8:41503840 NKX6-3 0.85 9.62 0.65 1.04e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs13064411 0.696 rs6766615 chr3:113219342 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9926296 0.565 rs8055825 chr16:89832848 C/T cg03388025 chr16:89894329 SPIRE2 0.48 8.35 0.6 1.15e-13 Vitiligo; TGCT cis rs8020441 0.891 rs112124522 chr14:51167502 G/A cg04730355 chr14:51134070 SAV1 0.73 6.02 0.48 1.81e-8 Cognitive performance; TGCT cis rs2180341 1.000 rs9285460 chr6:127640190 A/G cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg05025164 chr4:1340916 KIAA1530 -0.57 -4.96 -0.41 2.29e-6 Obesity-related traits; TGCT cis rs295140 1.000 rs3769476 chr2:201181428 T/C cg04283868 chr2:201171347 SPATS2L 0.65 6.66 0.51 7.99e-10 QT interval; TGCT cis rs1218582 0.741 rs10908446 chr1:154869559 G/A cg09359103 chr1:154839909 KCNN3 -0.67 -12.23 -0.74 4.77e-23 Prostate cancer; TGCT cis rs3026101 0.671 rs739766 chr17:5290599 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.57 0.38 1.16e-5 Body mass index; TGCT cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg17554472 chr22:41940697 POLR3H 0.43 4.6 0.38 1.01e-5 Vitiligo; TGCT cis rs7909074 1.000 rs4481983 chr10:45400428 G/T cg04218760 chr10:45406644 TMEM72 -0.27 -5.31 -0.43 4.88e-7 Mean corpuscular volume; TGCT cis rs10992471 0.603 rs7045572 chr9:95137964 T/C cg14631576 chr9:95140430 CENPP -0.33 -4.99 -0.41 2.02e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs950880 0.560 rs11679191 chr2:102926800 A/T cg09003973 chr2:102972529 NA -0.54 -4.72 -0.39 6.3e-6 Serum protein levels (sST2); TGCT cis rs2820315 0.867 rs2820321 chr1:201880296 G/C cg12730843 chr1:201915899 LMOD1 -0.27 -5.08 -0.41 1.37e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2862064 0.932 rs1553316 chr5:156479509 A/G cg12943317 chr5:156479607 HAVCR1 -0.45 -5.97 -0.47 2.31e-8 Platelet count; TGCT cis rs137699 0.559 rs137683 chr22:39738501 G/C cg24399712 chr22:39784796 NA -0.68 -5.31 -0.43 4.82e-7 IgG glycosylation; TGCT cis rs9902453 0.817 rs1842026 chr17:28188111 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.62e-11 Coffee consumption (cups per day); TGCT cis rs1008375 1.000 rs10032326 chr4:17630717 A/T cg18681998 chr4:17616180 MED28 1.01 11.33 0.71 7.13e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11190604 0.652 rs76629555 chr10:102191417 T/C cg16342193 chr10:102329863 NA -0.38 -5.0 -0.41 1.93e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs610932 0.517 rs621965 chr11:60004828 G/A cg18570331 chr11:60101691 MS4A6E 0.5 4.49 0.37 1.63e-5 Alzheimer's disease; TGCT cis rs2361718 0.631 rs4889989 chr17:78151860 C/G cg09238746 chr17:78121135 EIF4A3 0.78 7.15 0.54 6.47e-11 Yeast infection; TGCT cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs9486719 0.790 rs2499790 chr6:96845078 G/A cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs7267979 1.000 rs6115191 chr20:25440478 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7511006 1.000 rs7290710 chr22:50677454 C/T cg08875078 chr22:50639485 SELO 0.51 4.81 0.4 4.35e-6 Obesity-related traits; TGCT cis rs4499344 0.587 rs10407420 chr19:33054804 G/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.21 -0.49 7.33e-9 Mean platelet volume; TGCT cis rs13256369 1.000 rs10088439 chr8:8576699 T/G cg17143192 chr8:8559678 CLDN23 0.62 5.83 0.46 4.47e-8 Obesity-related traits; TGCT cis rs10504229 0.861 rs67966192 chr8:58188172 A/C cg22535103 chr8:58192502 C8orf71 -0.36 -4.72 -0.39 6.31e-6 Developmental language disorder (linguistic errors); TGCT cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.1 9.08 0.63 2.06e-15 Platelet count; TGCT cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg03452623 chr4:187889614 NA -0.33 -4.94 -0.41 2.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs2027003 chr20:25350498 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9818758 0.607 rs73074866 chr3:49626666 C/T cg07636037 chr3:49044803 WDR6 -0.98 -4.72 -0.39 6.18e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs614226 1.000 rs580016 chr12:120933977 T/C cg01236616 chr12:121019343 POP5 -1.23 -12.71 -0.75 3.22e-24 Type 1 diabetes nephropathy; TGCT cis rs12681287 0.752 rs4534114 chr8:87271956 A/G cg27223183 chr8:87520930 FAM82B -0.82 -5.86 -0.47 3.98e-8 Caudate activity during reward; TGCT cis rs9346649 0.630 rs6913441 chr6:168491271 C/T cg02770688 chr6:168491649 NA 0.31 5.74 0.46 6.95e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs2562456 0.917 rs2562466 chr19:21714204 C/T cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs9296092 0.517 rs56069946 chr6:33511136 G/A cg13560919 chr6:33536144 NA -0.2 -4.47 -0.37 1.75e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9911578 0.835 rs2301867 chr17:56480074 T/A cg12560992 chr17:57184187 TRIM37 -0.77 -8.97 -0.63 3.76e-15 Intelligence (multi-trait analysis); TGCT cis rs3015497 0.586 rs12587821 chr14:51092554 A/G cg04730355 chr14:51134070 SAV1 -0.64 -6.04 -0.48 1.64e-8 Mean platelet volume; TGCT cis rs7267979 1.000 rs2424700 chr20:25266513 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1878931 0.531 rs9635548 chr16:3417156 G/A cg22508957 chr16:3507546 NAT15 -0.38 -4.98 -0.41 2.1e-6 Body mass index (adult); TGCT cis rs1018836 0.923 rs4735256 chr8:91612145 C/G cg16814680 chr8:91681699 NA -0.86 -9.27 -0.64 7.49e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2439831 1.000 rs690002 chr15:43729349 C/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs854765 0.583 rs11078405 chr17:17824978 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.94 0.58 1.04e-12 Total body bone mineral density; TGCT cis rs2439831 0.850 rs7163245 chr15:43671294 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs950173 1.000 rs950173 chr2:172570419 G/A cg13550731 chr2:172543902 DYNC1I2 -1.0 -5.78 -0.46 5.57e-8 Hippocampal volume; TGCT cis rs5769765 0.908 rs9616388 chr22:50313438 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -13.17 -0.76 2.52e-25 Schizophrenia; TGCT cis rs208520 0.690 rs12198745 chr6:66722598 T/C cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs12048904 0.533 rs1590580 chr1:101292668 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.82 7.42 0.55 1.63e-11 Multiple sclerosis; TGCT cis rs651907 0.535 rs11716558 chr3:101528481 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.86 0.4 3.51e-6 Colorectal cancer; TGCT cis rs11098499 0.780 rs12504773 chr4:120562149 G/C cg09307838 chr4:120376055 NA 0.7 6.52 0.51 1.6e-9 Corneal astigmatism; TGCT cis rs9399137 0.507 rs4896129 chr6:135349845 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.97 0.41 2.22e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs7666738 0.822 rs13110418 chr4:99046963 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3862030 0.839 rs7078679 chr10:104284017 C/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.53 -5.15 -0.42 9.99e-7 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs909674 0.524 rs5750821 chr22:39825492 A/T cg24399712 chr22:39784796 NA -1.05 -12.52 -0.75 9.61e-24 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2980439 0.517 rs793753 chr8:8105359 T/G cg08975724 chr8:8085496 FLJ10661 -0.53 -4.85 -0.4 3.68e-6 Neuroticism; TGCT cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg06108461 chr20:60628389 TAF4 -0.7 -9.99 -0.67 1.32e-17 Body mass index; TGCT cis rs7843479 0.509 rs3758156 chr8:21770796 A/G cg17168535 chr8:21777572 XPO7 0.76 7.11 0.54 8.28e-11 Mean corpuscular volume; TGCT cis rs7412746 0.658 rs10888397 chr1:150886752 A/G cg09365446 chr1:150670422 GOLPH3L -0.33 -4.85 -0.4 3.58e-6 Melanoma; TGCT cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs1008375 0.932 rs4698627 chr4:17605959 T/C cg18681998 chr4:17616180 MED28 0.99 10.18 0.67 4.67e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs911263 0.961 rs2208397 chr14:68753287 T/G cg18825221 chr14:68749962 RAD51L1 0.28 5.31 0.43 4.82e-7 Primary biliary cholangitis; TGCT cis rs2486288 0.656 rs12911186 chr15:45551423 A/G cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs36051895 0.659 rs7862042 chr9:5268139 G/A cg02405213 chr9:5042618 JAK2 -0.63 -7.6 -0.56 6.32e-12 Pediatric autoimmune diseases; TGCT cis rs6582630 0.519 rs9738104 chr12:38338459 A/C cg13010199 chr12:38710504 ALG10B 0.61 4.77 0.39 5.11e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6543140 0.572 rs17027173 chr2:103057043 G/A cg09003973 chr2:102972529 NA 0.79 6.45 0.5 2.31e-9 Blood protein levels; TGCT cis rs709400 0.526 rs11622835 chr14:103967504 G/A cg26031613 chr14:104095156 KLC1 0.7 5.61 0.45 1.25e-7 Body mass index; TGCT trans rs1814175 0.645 rs28538913 chr11:50040718 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs12497850 0.931 rs9867373 chr3:48960938 A/T cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs7568458 0.846 rs1078004 chr2:85769711 C/G cg02493740 chr2:85810744 VAMP5 -0.29 -5.47 -0.44 2.42e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7666738 0.830 rs28485415 chr4:99060340 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10744422 0.858 rs10773627 chr12:123311853 A/G cg25930673 chr12:123319894 HIP1R -0.85 -5.01 -0.41 1.86e-6 Schizophrenia; TGCT cis rs2153535 0.580 rs9505458 chr6:8479215 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7909074 0.714 rs10900129 chr10:45398609 G/C cg05187965 chr10:45406764 TMEM72 -0.24 -4.84 -0.4 3.72e-6 Mean corpuscular volume; TGCT cis rs7639513 0.767 rs9878151 chr3:12703714 G/C cg23032965 chr3:12705835 RAF1 0.77 8.53 0.61 4.28e-14 Itch intensity from mosquito bite; TGCT cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg12310025 chr6:25882481 NA 0.5 4.49 0.37 1.58e-5 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg03517284 chr6:25882590 NA -0.52 -5.27 -0.43 5.77e-7 Blood metabolite levels; TGCT cis rs73110464 0.505 rs2682296 chr12:53308265 G/A cg05393297 chr12:53359155 NA -0.45 -5.08 -0.41 1.37e-6 Cancer (pleiotropy); TGCT cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg13770153 chr20:60521292 NA 0.6 8.74 0.62 1.36e-14 Obesity-related traits; TGCT cis rs7412746 0.597 rs868751 chr1:150669414 T/G cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Melanoma; TGCT cis rs7267979 0.966 rs2257712 chr20:25264910 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3820068 0.608 rs7514858 chr1:16035246 G/A cg17385448 chr1:15911702 AGMAT 0.36 4.92 0.4 2.67e-6 Systolic blood pressure; TGCT cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg08859206 chr1:53392774 SCP2 0.39 5.8 0.46 5.07e-8 Monocyte count; TGCT trans rs3780486 0.846 rs10738905 chr9:33123627 A/G cg20290983 chr6:43655470 MRPS18A 1.21 15.13 0.81 5.99e-30 IgG glycosylation; TGCT cis rs3733585 0.699 rs7683283 chr4:9969974 T/C cg00071950 chr4:10020882 SLC2A9 -0.57 -6.83 -0.52 3.41e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs17601876 0.814 rs8042086 chr15:51561478 C/T cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs739496 0.615 rs609230 chr12:112146911 A/G cg10833066 chr12:111807467 FAM109A -0.37 -4.79 -0.39 4.76e-6 Platelet count; TGCT cis rs1878931 0.501 rs9921169 chr16:3421261 A/T cg05754148 chr16:3507555 NAT15 -0.33 -4.46 -0.37 1.82e-5 Body mass index (adult); TGCT cis rs2153535 0.580 rs6913100 chr6:8456855 A/G cg23788917 chr6:8435910 SLC35B3 0.62 5.62 0.45 1.2e-7 Motion sickness; TGCT cis rs7829975 0.582 rs448231 chr8:8790059 A/T cg06636001 chr8:8085503 FLJ10661 -0.74 -7.26 -0.55 3.67e-11 Mood instability; TGCT cis rs910316 0.935 rs11159119 chr14:75636967 C/T cg23033748 chr14:75592666 NEK9 -0.28 -4.77 -0.39 4.98e-6 Height; TGCT cis rs273909 0.514 rs77450473 chr5:131785536 G/A cg24060327 chr5:131705240 SLC22A5 0.64 4.49 0.37 1.61e-5 Coronary artery disease; TGCT cis rs8031584 0.752 rs34722914 chr15:31191991 G/A cg08704250 chr15:31115839 NA -0.42 -6.28 -0.49 5.27e-9 Huntington's disease progression; TGCT cis rs7666738 0.830 rs7672901 chr4:98938781 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9650657 0.740 rs6980805 chr8:10679842 G/C cg27411982 chr8:10470053 RP1L1 -0.23 -5.11 -0.42 1.17e-6 Neuroticism; TGCT cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg11941060 chr3:133502564 NA -0.26 -5.43 -0.44 2.88e-7 Iron status biomarkers; TGCT cis rs9916302 0.904 rs12452509 chr17:37574722 G/A cg15445000 chr17:37608096 MED1 0.34 4.8 0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs2342371 0.701 rs4916498 chr3:196202961 G/C cg15048948 chr3:196158458 UBXN7 -0.54 -4.62 -0.38 9.56e-6 Fat distribution (HIV); TGCT cis rs7178572 0.524 rs12914128 chr15:77493875 T/C cg15453836 chr15:77711506 NA -0.44 -4.91 -0.4 2.86e-6 Type 2 diabetes; TGCT cis rs2832191 0.720 rs7277028 chr21:30494604 T/C cg24692254 chr21:30365293 RNF160 -0.92 -9.97 -0.67 1.45e-17 Dental caries; TGCT cis rs7267979 1.000 rs6050609 chr20:25411751 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7000551 0.560 rs4872483 chr8:22255684 C/T cg12081754 chr8:22256438 SLC39A14 0.32 5.08 0.41 1.36e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4722166 0.630 rs10950916 chr7:22799667 C/T cg26061582 chr7:22766209 IL6 0.5 6.49 0.5 1.88e-9 Lung cancer; TGCT cis rs782590 0.967 rs11125581 chr2:55796527 C/G cg03859395 chr2:55845619 SMEK2 0.9 11.19 0.71 1.64e-20 Metabolic syndrome; TGCT cis rs7017914 0.905 rs2732114 chr8:71928712 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs60111824 1 rs60111824 chr7:6774135 A/G cg11074378 chr7:5938227 C7orf28A -0.88 -4.53 -0.38 1.36e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2224391 0.628 rs2753239 chr6:5252826 C/A cg09085698 chr6:5261316 LYRM4;FARS2 -0.99 -6.43 -0.5 2.46e-9 Height; TGCT cis rs7192750 0.617 rs9929256 chr16:72040032 A/C cg06353428 chr16:71660113 MARVELD3 1.01 5.63 0.45 1.14e-7 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9640161 0.659 rs11975886 chr7:150010362 G/A cg17279839 chr7:150038598 RARRES2 0.42 4.45 0.37 1.88e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs10927875 0.541 rs1739842 chr1:16342848 T/G cg21385522 chr1:16154831 NA 0.46 4.75 0.39 5.5e-6 Dilated cardiomyopathy; TGCT cis rs6543140 0.927 rs917999 chr2:103067869 G/A cg09003973 chr2:102972529 NA 0.56 4.67 0.39 7.86e-6 Blood protein levels; TGCT cis rs13326165 0.760 rs2335640 chr3:52368387 T/C cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6540559 0.673 rs11803382 chr1:209986426 G/A cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT cis rs79976124 0.879 rs17511467 chr6:66627293 T/C cg07460842 chr6:66804631 NA 0.58 5.32 0.43 4.77e-7 Type 2 diabetes; TGCT cis rs317689 0.819 rs317685 chr12:69715457 A/G cg14784868 chr12:69753453 YEATS4 -0.58 -5.01 -0.41 1.79e-6 Response to diuretic therapy; TGCT cis rs8062405 0.824 rs62034324 chr16:28536762 T/C cg09754948 chr16:28834200 ATXN2L 0.58 4.57 0.38 1.14e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6964587 1.000 rs13245393 chr7:91641928 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs13256369 1.000 rs10110591 chr8:8576608 G/T cg17143192 chr8:8559678 CLDN23 -0.6 -5.56 -0.45 1.59e-7 Obesity-related traits; TGCT cis rs6831352 0.842 rs1230156 chr4:99989626 C/T cg12011299 chr4:100065546 ADH4 0.37 4.62 0.38 9.6e-6 Alcohol dependence; TGCT cis rs10791097 0.694 rs4456262 chr11:130755813 C/T cg05962950 chr11:130786565 SNX19 -0.94 -6.71 -0.52 6.14e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg12310025 chr6:25882481 NA -0.7 -7.48 -0.56 1.17e-11 Blood metabolite levels; TGCT cis rs763014 0.898 rs1981484 chr16:630710 A/G cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs72945132 0.882 rs67529561 chr11:70162055 G/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs3213545 0.659 rs2259690 chr12:121457914 T/G cg02403541 chr12:121454288 C12orf43 0.7 7.9 0.58 1.3e-12 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs739496 0.563 rs7484754 chr12:112047296 T/A cg10833066 chr12:111807467 FAM109A 0.36 4.98 0.41 2.1e-6 Platelet count; TGCT cis rs7818688 0.591 rs10098025 chr8:95989583 T/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs2288884 1.000 rs79817140 chr19:52571657 C/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs10507380 0.824 rs75857247 chr13:27926133 A/C cg25543773 chr13:27185723 WASF3 0.32 4.52 0.38 1.45e-5 Electrocardiographic traits; TGCT cis rs1971762 0.545 rs876252 chr12:54071422 A/G cg16917193 chr12:54089295 NA 1.15 12.16 0.74 7.16e-23 Height; TGCT cis rs3617 0.591 rs2276823 chr3:52869263 C/A cg10802521 chr3:52805072 NEK4 0.63 7.34 0.55 2.49e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg09177884 chr7:1199841 ZFAND2A -0.51 -4.97 -0.41 2.21e-6 Longevity;Endometriosis; TGCT trans rs629535 0.814 rs558511 chr8:70069908 C/A cg21567404 chr3:27674614 NA 0.57 9.11 0.63 1.82e-15 Dupuytren's disease; TGCT cis rs9486715 0.964 rs6921480 chr6:97066329 C/G cg18709589 chr6:96969512 KIAA0776 -0.77 -7.12 -0.54 7.74e-11 Headache; TGCT cis rs7829975 0.688 rs7826654 chr8:8379106 C/T cg15556689 chr8:8085844 FLJ10661 0.67 6.2 0.49 7.84e-9 Mood instability; TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.12 15.93 0.82 8.93e-32 Prudent dietary pattern; TGCT cis rs10165862 0.572 rs11674212 chr2:73911180 C/T cg07208825 chr2:73871855 ALMS1P 0.23 4.88 0.4 3.15e-6 Intelligence (multi-trait analysis); TGCT cis rs9372498 0.505 rs9489462 chr6:118927855 C/T cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs7192750 0.562 rs9302632 chr16:71943511 A/G cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs644799 1.000 rs611020 chr11:95567905 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.83 7.88 0.58 1.4e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.62 -0.38 9.64e-6 Bipolar disorder; TGCT cis rs739496 0.512 rs73422315 chr12:112268299 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7949030 0.626 rs72927213 chr11:62351198 G/C cg11742103 chr11:62369870 EML3;MTA2 0.6 8.63 0.61 2.53e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7659604 0.540 rs9998385 chr4:122676673 C/T cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs1055129 0.584 rs9895947 chr17:73908566 A/C cg10935138 chr17:73851978 WBP2 0.57 4.87 0.4 3.34e-6 White matter hyperintensity burden; TGCT cis rs904251 0.523 rs2776871 chr6:37481759 A/G cg01843034 chr6:37503916 NA -0.56 -7.56 -0.56 7.84e-12 Cognitive performance; TGCT cis rs875971 1.000 rs10215948 chr7:65747786 G/A cg18876405 chr7:65276391 NA -0.34 -5.09 -0.42 1.27e-6 Aortic root size; TGCT cis rs9300255 0.569 rs1727320 chr12:123700476 T/A cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs2153535 0.580 rs1414351 chr6:8476634 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs72945132 0.882 rs60780459 chr11:70162468 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs4478037 0.558 rs55980934 chr3:33081696 C/T cg19404215 chr3:33155277 CRTAP 1.04 4.95 0.41 2.36e-6 Major depressive disorder; TGCT cis rs3617 0.539 rs11130331 chr3:52956918 G/A cg05573699 chr3:52720067 GNL3;PBRM1 0.46 4.49 0.37 1.58e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg26338869 chr17:61819248 STRADA -0.52 -4.75 -0.39 5.48e-6 Prudent dietary pattern; TGCT cis rs854765 0.663 rs6502618 chr17:17746741 A/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.52 -0.38 1.45e-5 Total body bone mineral density; TGCT cis rs12643440 0.574 rs1581400 chr4:17139504 A/G cg22650099 chr4:17144496 NA -0.45 -4.65 -0.39 8.28e-6 Metabolite levels (Pyroglutamine); TGCT cis rs4478858 0.684 rs3737755 chr1:31744168 G/A cg07478791 chr1:31886160 SERINC2 -0.48 -4.6 -0.38 1.05e-5 Alcohol dependence; TGCT cis rs2658782 0.756 rs3019222 chr11:93079718 C/T cg18152523 chr11:93063302 CCDC67 -0.67 -5.19 -0.42 8.29e-7 Pulmonary function decline; TGCT cis rs2204008 0.540 rs1283306 chr12:38153778 C/A cg26384229 chr12:38710491 ALG10B -0.58 -5.08 -0.42 1.33e-6 Bladder cancer; TGCT cis rs2836950 0.565 rs2836942 chr21:40591381 A/G cg11890956 chr21:40555474 PSMG1 -0.68 -6.67 -0.51 7.62e-10 Menarche (age at onset); TGCT cis rs56235845 0.694 rs11738681 chr5:176761535 A/G cg16006841 chr5:176797999 RGS14 0.49 7.31 0.55 2.9100000000000002e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs2880765 0.835 rs7161880 chr15:86018746 C/T cg13263323 chr15:86062960 AKAP13 -0.22 -4.74 -0.39 5.67e-6 Coronary artery disease; TGCT cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs200810 0.694 rs4839913 chr6:98019234 C/G cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.71 -4.78 -0.39 4.89e-6 Body mass index; TGCT cis rs11711311 0.910 rs62265549 chr3:113396234 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.8 -7.16 -0.54 6.18e-11 IgG glycosylation; TGCT cis rs73110464 0.609 rs11170348 chr12:53355588 A/G cg14581129 chr12:53358946 NA -0.63 -6.78 -0.52 4.39e-10 Cancer (pleiotropy); TGCT cis rs10791323 0.546 rs55801927 chr11:133713094 A/C cg03690763 chr11:133734501 NA -0.31 -4.92 -0.4 2.73e-6 Childhood ear infection; TGCT cis rs453301 0.522 rs2929309 chr8:9083771 C/A cg06636001 chr8:8085503 FLJ10661 -0.55 -4.8 -0.4 4.51e-6 Joint mobility (Beighton score); TGCT cis rs11997175 0.524 rs10954932 chr8:33650176 A/C ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.3e-5 Body mass index; TGCT trans rs10109025 0.670 rs7825690 chr8:10858257 G/T cg06636001 chr8:8085503 FLJ10661 -0.79 -7.49 -0.56 1.11e-11 Joint mobility (Beighton score); TGCT cis rs597539 0.690 rs578791 chr11:68625809 C/T cg06028808 chr11:68637592 NA 0.56 6.93 0.53 2.08e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11621121 0.556 rs11158588 chr14:65799876 G/A cg04536575 chr14:65016802 C14orf50 -0.63 -4.49 -0.37 1.61e-5 N-glycan levels; TGCT cis rs7267979 0.966 rs6037103 chr20:25369095 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs929354 1.000 rs1182410 chr7:157063837 C/T cg05182265 chr7:156933206 UBE3C 0.3 6.39 0.5 3.05e-9 Body mass index; TGCT trans rs7618501 0.966 rs7372966 chr3:49788969 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs9991512 chr4:99007205 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1475911 1.000 rs12482477 chr21:43517233 T/A cg19766460 chr21:43528205 UMODL1;C21orf128 0.51 7.02 0.53 1.3e-10 IgG glycosylation; TGCT cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg25036284 chr2:26402008 FAM59B -0.61 -4.89 -0.4 3.1e-6 Gut microbiome composition (summer); TGCT trans rs1814175 0.791 rs7395713 chr11:49877887 A/G cg15704280 chr7:45808275 SEPT13 -0.71 -7.9 -0.58 1.27e-12 Height; TGCT cis rs9807989 0.801 rs10173193 chr2:102975050 G/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs1577917 0.958 rs12198971 chr6:86525445 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs40363 0.645 rs250630 chr16:3524242 C/T cg22508957 chr16:3507546 NAT15 0.5 5.79 0.46 5.49e-8 Tuberculosis; TGCT cis rs593982 1.000 rs593982 chr11:65513107 T/C cg08755490 chr11:65554678 OVOL1 1.42 12.09 0.74 1.03e-22 Atopic dermatitis; TGCT cis rs68170813 0.559 rs6964966 chr7:106933099 C/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs6088580 0.634 rs6120666 chr20:33090718 A/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs12908161 0.959 rs2175567 chr15:85200946 C/G cg12863693 chr15:85201151 NMB 0.46 5.54 0.45 1.73e-7 Schizophrenia; TGCT cis rs12541335 0.639 rs35068739 chr8:22201719 T/C cg26039829 chr8:22132926 PIWIL2 0.27 5.12 0.42 1.14e-6 Hypertriglyceridemia; TGCT cis rs10782582 0.593 rs114421765 chr1:76141802 C/T cg10523679 chr1:76189770 ACADM -0.68 -7.06 -0.54 1.03e-10 Daytime sleep phenotypes; TGCT cis rs13242816 1.000 rs62468976 chr7:116126891 C/G cg02799643 chr7:116139180 CAV2 -0.45 -5.46 -0.44 2.49e-7 P wave duration; TGCT cis rs72945132 0.882 rs11235739 chr11:70132780 C/T cg00319359 chr11:70116639 PPFIA1 1.01 7.58 0.56 7.09e-12 Coronary artery disease; TGCT cis rs9326248 0.581 rs10892072 chr11:116960313 G/A cg20608306 chr11:116969690 SIK3 0.4 4.52 0.38 1.4e-5 Blood protein levels; TGCT cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs7809950 0.637 rs2701685 chr7:107299584 A/G cg23024343 chr7:107201750 COG5 0.41 5.78 0.46 5.71e-8 Coronary artery disease; TGCT cis rs7192750 0.583 rs2550043 chr16:72067491 T/C cg06353428 chr16:71660113 MARVELD3 0.98 4.87 0.4 3.27e-6 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg03396347 chr1:1875803 NA -0.37 -6.63 -0.51 9.38e-10 Body mass index; TGCT cis rs4819052 0.808 rs2838825 chr21:46655651 C/T cg06618935 chr21:46677482 NA -0.34 -5.29 -0.43 5.26e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.41 -4.88 -0.4 3.13e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs3917265 0.602 rs3917290 chr2:102782079 C/T cg17937070 chr2:102766322 NA -0.32 -4.48 -0.37 1.66e-5 Atopic dermatitis; TGCT cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs2235642 1.000 rs2076438 chr16:1584618 T/C cg08296037 chr16:1584118 IFT140;TMEM204 -0.3 -5.51 -0.44 2.01e-7 Coronary artery disease; TGCT cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg04608855 chr19:58913158 NA 0.53 5.06 0.41 1.49e-6 Uric acid clearance; TGCT cis rs1843834 0.929 rs4674934 chr2:225516468 A/T cg22455342 chr2:225449267 CUL3 -0.72 -7.29 -0.55 3.15e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs9611519 0.780 rs3171692 chr22:41642212 C/T cg06634786 chr22:41940651 POLR3H -0.56 -5.05 -0.41 1.52e-6 Neuroticism; TGCT cis rs727563 0.635 rs713988 chr22:42159072 A/G cg13695892 chr22:41940480 POLR3H 0.87 8.24 0.59 2.06e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10883723 0.773 rs11191303 chr10:104255158 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12142240 0.698 rs17357711 chr1:46829013 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs2455799 0.614 rs2881211 chr3:15866983 C/T cg12172478 chr3:16357591 RFTN1 -0.33 -4.86 -0.4 3.47e-6 Mean platelet volume; TGCT cis rs1218582 0.774 rs4845681 chr1:154868055 G/T cg16680214 chr1:154839983 KCNN3 -0.42 -9.08 -0.63 2.15e-15 Prostate cancer; TGCT cis rs838147 0.563 rs2638282 chr19:49213833 G/A cg13540341 chr19:49222985 MAMSTR -0.36 -4.66 -0.39 7.98e-6 Dietary macronutrient intake; TGCT cis rs7666738 0.830 rs11735193 chr4:98761900 C/T cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs11097598 chr4:98946057 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6933660 0.745 rs3800272 chr6:151744283 A/G cg10883421 chr6:151773342 RMND1;C6orf211 -0.56 -5.53 -0.44 1.8e-7 Menarche (age at onset); TGCT cis rs7666738 0.830 rs4699603 chr4:99056172 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs31872 0.521 rs246050 chr5:140326860 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Visceral adipose tissue adjusted for BMI; TGCT trans rs208520 1.000 rs12191598 chr6:66983962 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs13177918 0.677 rs3900644 chr5:149822922 T/A cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9926296 0.609 rs4785710 chr16:89796756 C/T cg27121462 chr16:89883253 FANCA -0.55 -5.27 -0.43 5.81e-7 Vitiligo; TGCT trans rs7819412 0.806 rs6980856 chr8:10938260 A/G cg15556689 chr8:8085844 FLJ10661 0.84 8.16 0.59 3.26e-13 Triglycerides; TGCT cis rs9467773 0.967 rs1535276 chr6:26520941 T/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT trans rs208515 0.525 rs1484577 chr6:66688397 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.92 10.09 0.67 7.45e-18 Exhaled nitric oxide levels; TGCT cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2692947 0.673 rs2692894 chr2:96784934 T/G cg05933789 chr2:97190408 NA -0.17 -4.87 -0.4 3.39e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs12479064 0.724 rs11885942 chr2:100004165 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -6.33 -0.49 4.06e-9 Chronic sinus infection; TGCT cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg27286337 chr10:134555280 INPP5A 0.39 4.73 0.39 6.02e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs10892173 0.566 rs111578166 chr11:117666714 G/T cg21640587 chr11:117668038 DSCAML1 0.65 7.53 0.56 9.06e-12 Myopia; TGCT cis rs4499344 0.589 rs259218 chr19:33138125 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.28 0.6 1.68e-13 Mean platelet volume; TGCT cis rs10276381 0.786 rs73089302 chr7:28187134 G/A cg23620719 chr7:28220237 JAZF1 1.01 5.82 0.46 4.75e-8 Crohn's disease; TGCT cis rs1215050 0.740 rs783945 chr4:99014394 G/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.99 -0.41 1.95e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs35235971 chr4:98999833 G/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs17030434 0.784 rs10032475 chr4:154674748 C/T cg14289246 chr4:154710475 SFRP2 -0.81 -6.76 -0.52 4.73e-10 Electrocardiographic conduction measures; TGCT cis rs12477438 0.735 rs12474477 chr2:99690408 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.85 -0.47 4.06e-8 Chronic sinus infection; TGCT cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg07424592 chr7:64974309 NA 1.34 8.26 0.6 1.81e-13 Diabetic kidney disease; TGCT cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg11062466 chr8:58055876 NA 0.46 4.81 0.4 4.29e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115738062 chr4:119725490 C/T cg14228332 chr4:119757509 SEC24D 1.38 6.93 0.53 2.07e-10 Cannabis dependence symptom count; TGCT cis rs941408 1.000 rs2260416 chr19:2796355 G/A cg06609049 chr19:2785107 THOP1 0.79 7.46 0.56 1.34e-11 Total cholesterol levels; TGCT cis rs910187 0.537 rs1417452 chr20:45763350 T/C cg27589058 chr20:45804311 EYA2 -0.34 -6.28 -0.49 5.1e-9 Migraine; TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg18948646 chr4:83674694 SCD5;MIR575 0.57 6.94 0.53 1.98e-10 Breast cancer; TGCT cis rs2307449 0.729 rs1006659 chr15:89883672 T/G cg24365117 chr15:89879190 POLG 0.3 4.47 0.37 1.74e-5 Menopause (age at onset); TGCT cis rs7208859 0.673 rs9895684 chr17:29242600 G/A cg14008862 chr17:28927542 LRRC37B2 0.73 4.71 0.39 6.49e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6912958 0.935 rs2179844 chr6:88165773 C/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.22 -0.49 7.06e-9 Monocyte percentage of white cells; TGCT cis rs8028182 0.636 rs8023815 chr15:75814704 G/A cg20655648 chr15:75932815 IMP3 0.59 4.62 0.38 9.55e-6 Sudden cardiac arrest; TGCT cis rs425277 0.606 rs2257684 chr1:2077872 A/G cg24578937 chr1:2090814 PRKCZ 0.26 6.95 0.53 1.8e-10 Height; TGCT cis rs2956278 0.717 rs2929752 chr12:84677004 G/A cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT trans rs10504390 0.656 rs79932695 chr8:66547075 T/C cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.29e-10 IgG glycosylation; TGCT cis rs10465746 0.905 rs34274953 chr1:84415011 G/A cg10977910 chr1:84465055 TTLL7 0.65 6.56 0.51 1.31e-9 Obesity-related traits; TGCT cis rs11154851 1.000 rs9321547 chr6:136307525 A/G cg00082954 chr6:136878319 MAP3K5 0.73 4.49 0.37 1.59e-5 Alzheimer's disease (cognitive decline); TGCT cis rs7267979 0.565 rs6107059 chr20:25592431 C/A cg14121845 chr20:25566513 NINL -0.41 -4.48 -0.37 1.7e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg05368731 chr17:41323189 NBR1 1.13 13.37 0.77 8.37e-26 Menopause (age at onset); TGCT cis rs9372253 1.000 rs9386894 chr6:110718853 A/G cg01119278 chr6:110721349 DDO -0.37 -5.94 -0.47 2.7e-8 Platelet distribution width; TGCT cis rs2153535 0.563 rs1796687 chr6:8536118 C/G cg07606381 chr6:8435919 SLC35B3 0.53 4.98 0.41 2.09e-6 Motion sickness; TGCT cis rs9473924 0.505 rs9463664 chr6:50902570 T/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs921968 0.541 rs578450 chr2:219401237 C/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT trans rs11088226 0.645 rs2833904 chr21:33941089 T/C cg09050820 chr6:167586206 TCP10L2 0.81 7.3 0.55 2.98e-11 Gastritis; TGCT cis rs11190604 1.000 rs3750633 chr10:102308214 C/T cg23241863 chr10:102295624 HIF1AN 0.7 5.18 0.42 8.9e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11190604 1.000 rs79831012 chr10:102237059 T/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9816226 0.618 rs1516728 chr3:185829891 A/T cg00760338 chr3:185826511 ETV5 0.73 6.37 0.5 3.42e-9 Obesity;Body mass index; TGCT cis rs707040 0.961 rs35706065 chr2:155235853 G/T cg18104148 chr2:154337490 NA 0.19 4.56 0.38 1.2e-5 Sudden cardiac arrest; TGCT cis rs3812831 0.695 rs6560935 chr13:114945867 G/A cg08824895 chr13:115047677 UPF3A 0.49 4.7 0.39 6.79e-6 Schizophrenia; TGCT cis rs709400 0.663 rs11626787 chr14:103991749 A/G cg12935359 chr14:103987150 CKB -0.39 -5.77 -0.46 5.87e-8 Body mass index; TGCT cis rs7312933 0.558 rs2178753 chr12:42732804 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.72 -0.46 7.52e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs3784262 1.000 rs12903551 chr15:58268372 C/T cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.74 -0.57 3.01e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs2469997 1.000 rs2470006 chr8:120358591 G/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs911263 0.961 rs3784099 chr14:68749927 A/G cg18825221 chr14:68749962 RAD51L1 0.25 4.98 0.41 2.05e-6 Primary biliary cholangitis; TGCT cis rs7582180 0.739 rs4851292 chr2:100924761 A/G cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs4635969 1.000 rs4635969 chr5:1308552 C/T cg18250916 chr5:612533 CEP72 0.49 4.51 0.38 1.5e-5 Testicular germ cell tumor;Testicular germ cell cancer; TGCT cis rs7904368 0.568 rs7075036 chr10:16864810 C/T cg14835575 chr10:16859367 RSU1 0.45 5.33 0.43 4.42e-7 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs2658782 0.789 rs56091149 chr11:93073640 A/C cg15737290 chr11:93063684 CCDC67 -0.84 -5.36 -0.43 3.99e-7 Pulmonary function decline; TGCT cis rs35883536 0.647 rs55728953 chr1:101046863 T/C cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs9796 0.621 rs12324159 chr15:41462468 G/A cg18705301 chr15:41695430 NDUFAF1 -0.54 -7.22 -0.54 4.66e-11 Menopause (age at onset); TGCT cis rs1005277 0.579 rs2474586 chr10:38418882 T/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs8038465 0.967 rs3935942 chr15:73971361 C/A cg15420318 chr15:73925796 NPTN 0.7 6.53 0.51 1.56e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8020441 0.588 rs59096640 chr14:51186392 G/C cg04730355 chr14:51134070 SAV1 1.04 7.27 0.55 3.55e-11 Cognitive performance; TGCT cis rs9325144 0.555 rs12424003 chr12:38688140 C/T cg26384229 chr12:38710491 ALG10B -0.65 -6.01 -0.48 1.9e-8 Morning vs. evening chronotype; TGCT cis rs7647973 0.925 rs4955421 chr3:49218888 G/A cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.79 -0.4 4.63e-6 Menarche (age at onset); TGCT cis rs6725041 0.819 rs13420153 chr2:213083191 C/G cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs2836950 0.565 rs7276046 chr21:40581293 T/C cg11644478 chr21:40555479 PSMG1 -0.49 -4.56 -0.38 1.21e-5 Menarche (age at onset); TGCT cis rs4780401 0.609 rs4780399 chr16:11828701 A/T cg01061890 chr16:11836724 TXNDC11 -0.57 -5.42 -0.44 3.05e-7 Rheumatoid arthritis; TGCT cis rs17221829 0.733 rs11018726 chr11:89413265 T/C cg02982614 chr11:89391479 FOLH1B -0.28 -4.66 -0.39 7.94e-6 Anxiety in major depressive disorder; TGCT cis rs9611565 0.559 rs132768 chr22:42013523 C/A cg03806693 chr22:41940476 POLR3H 1.07 11.4 0.72 4.95e-21 Vitiligo; TGCT cis rs17122693 1.000 rs17122674 chr14:51066429 G/A cg04730355 chr14:51134070 SAV1 1.15 7.71 0.57 3.48e-12 Cognitive performance; TGCT cis rs4704846 1.000 rs10067589 chr5:156524999 C/T cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs9913156 0.793 rs55974786 chr17:4567564 T/C cg19197139 chr17:4613644 ARRB2 0.86 7.97 0.58 8.69e-13 Lymphocyte counts; TGCT cis rs79349575 0.715 rs4793997 chr17:47019672 C/A cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs9926296 0.569 rs4785708 chr16:89796569 C/T cg04287289 chr16:89883240 FANCA -0.61 -6.02 -0.48 1.85e-8 Vitiligo; TGCT cis rs6714710 0.603 rs34974566 chr2:98552299 C/G cg26665480 chr2:98280029 ACTR1B 0.63 5.99 0.47 2.13e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs941408 1.000 rs941407 chr19:2812153 A/G cg06609049 chr19:2785107 THOP1 0.84 8.23 0.59 2.16e-13 Total cholesterol levels; TGCT cis rs8078723 0.738 rs8066582 chr17:38146929 A/G cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7017914 0.934 rs3110239 chr8:71916745 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.31 -0.43 4.8e-7 Bone mineral density; TGCT cis rs9807989 0.839 rs1362348 chr2:102984624 C/G cg09003973 chr2:102972529 NA 0.64 5.76 0.46 6.37e-8 Asthma; TGCT cis rs72768842 1.000 rs72768817 chr5:78944371 G/C cg24834873 chr5:79865402 ANKRD34B -1.16 -4.61 -0.38 9.84e-6 Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs4372836 0.504 rs13025081 chr2:29083850 C/A cg09522027 chr2:28974177 PPP1CB -0.57 -5.63 -0.45 1.14e-7 Body mass index; TGCT cis rs34526934 0.566 rs34028621 chr2:177042779 C/T cg26754761 chr2:177040938 NA -0.29 -5.39 -0.44 3.35e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs12776158 0.901 rs60110374 chr10:71217090 C/T cg12610070 chr10:71211762 TSPAN15 -0.59 -5.17 -0.42 9.16e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9733 0.519 rs1336899 chr1:150678910 T/C cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs1843834 0.858 rs6731785 chr2:225491143 A/G cg22455342 chr2:225449267 CUL3 0.8 7.99 0.58 8.11e-13 IgE levels in asthmatics (D.p. specific); TGCT cis rs3087591 1.000 rs2952982 chr17:29470646 A/C cg24425628 chr17:29625626 OMG;NF1 0.48 7.63 0.57 5.39e-12 Hip circumference; TGCT cis rs68170813 0.559 rs79026644 chr7:107031803 A/G cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs10504229 0.636 rs77691549 chr8:58055126 G/T cg02725872 chr8:58115012 NA -0.38 -4.69 -0.39 7.12e-6 Developmental language disorder (linguistic errors); TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg14159672 chr1:205819179 PM20D1 -0.58 -7.11 -0.54 8.04e-11 Monocyte percentage of white cells; TGCT cis rs981844 1.000 rs2606327 chr4:154653629 C/T cg14289246 chr4:154710475 SFRP2 1.02 8.98 0.63 3.61e-15 Response to statins (LDL cholesterol change); TGCT cis rs77236434 0.579 rs1671368 chr8:13190714 C/G cg07307335 chr8:12602187 LONRF1 0.33 4.62 0.38 9.32e-6 Familial hepatitis B virus-related hepatocellular carcinoma; TGCT cis rs9883204 1.000 rs34970607 chr3:123090360 G/A cg04890266 chr3:123102914 ADCY5 0.36 5.1 0.42 1.26e-6 Birth weight; TGCT cis rs3751972 0.641 rs7212926 chr17:26235226 T/C cg02948944 chr17:26242737 NA 0.39 5.53 0.44 1.79e-7 Fractional exhaled nitric oxide (childhood); TGCT trans rs901683 0.702 rs74940001 chr10:46144294 G/A cg03466342 chr12:52753899 KRT85 -0.58 -7.16 -0.54 6.39e-11 Red blood cell traits;Mean corpuscular volume; TGCT cis rs1994135 0.669 rs10844628 chr12:33697065 T/C cg06521331 chr12:34319734 NA -0.3 -4.73 -0.39 6.09e-6 Resting heart rate; TGCT cis rs7586879 0.658 rs7563204 chr2:25125075 T/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs7727544 0.735 rs272842 chr5:131656517 A/G cg24060327 chr5:131705240 SLC22A5 -0.55 -6.18 -0.48 8.66e-9 Blood metabolite levels; TGCT cis rs9467773 0.967 rs9467775 chr6:26513435 G/A cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9952991 0.941 rs2847278 chr18:12778715 C/T cg09945482 chr18:12777974 NA 0.51 4.86 0.4 3.47e-6 Inflammatory skin disease; TGCT cis rs2486288 0.656 rs8039153 chr15:45579813 T/C cg26924012 chr15:45694286 SPATA5L1 -0.81 -8.48 -0.61 5.52e-14 Glomerular filtration rate; TGCT cis rs12142240 0.698 rs72677596 chr1:46833930 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.78 0.46 5.69e-8 Menopause (age at onset); TGCT cis rs9902453 0.791 rs6505141 chr17:27998187 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.26 0.6 1.9e-13 Coffee consumption (cups per day); TGCT cis rs7666738 0.830 rs7689495 chr4:98920152 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.23 0.43 6.88e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8056742 0.908 rs55757943 chr16:85094261 A/G cg00229868 chr16:85520891 NA 0.34 4.98 0.41 2.07e-6 Amyotrophic lateral sclerosis; TGCT cis rs12579753 0.871 rs10862362 chr12:82199383 T/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs6693567 0.565 rs35784258 chr1:150405882 T/C cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs9388451 0.626 rs3799708 chr6:126078530 C/T cg05901451 chr6:126070800 HEY2 -0.98 -12.53 -0.75 9.05e-24 Brugada syndrome; TGCT cis rs6938 0.563 rs12917376 chr15:75116167 C/T cg13906792 chr15:75199810 C15orf17 -0.2 -4.54 -0.38 1.34e-5 Breast cancer; TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.29 0.55 3.27e-11 Prudent dietary pattern; TGCT cis rs28595532 1.000 rs115706377 chr4:119628481 G/A cg14228332 chr4:119757509 SEC24D 1.0 5.76 0.46 6.22e-8 Cannabis dependence symptom count; TGCT cis rs1008375 1.000 rs10805357 chr4:17652352 G/A cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7833790 0.676 rs7834555 chr8:82697625 A/G cg27398817 chr8:82754497 SNX16 -0.58 -4.66 -0.39 8.19e-6 Diastolic blood pressure; TGCT cis rs6570726 0.935 rs380433 chr6:145859601 A/T cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7923452 0.507 rs103441 chr10:30778184 C/T cg18806716 chr10:30721971 MAP3K8 -0.63 -7.2 -0.54 4.97e-11 Itch intensity from mosquito bite; TGCT cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg06481639 chr22:41940642 POLR3H -0.72 -6.25 -0.49 6.08e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4665809 0.838 rs7565843 chr2:26292912 G/C cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs1865760 0.602 rs9467662 chr6:26021327 G/A cg17042849 chr6:26104293 HIST1H4C -0.61 -5.13 -0.42 1.07e-6 Height; TGCT cis rs9527 0.662 rs4919686 chr10:104592249 A/C cg15744005 chr10:104629667 AS3MT -0.47 -5.6 -0.45 1.33e-7 Arsenic metabolism; TGCT cis rs2034088 0.591 rs4968166 chr17:404537 C/T cg01214346 chr17:406501 NA -0.36 -5.48 -0.44 2.25e-7 Hip circumference adjusted for BMI; TGCT cis rs1215050 0.740 rs9994227 chr4:98767094 T/G cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7044106 0.791 rs7043969 chr9:123493989 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.77 0.39 4.99e-6 Hip circumference adjusted for BMI; TGCT cis rs6121246 0.559 rs6060599 chr20:30257754 T/G cg13852791 chr20:30311386 BCL2L1 0.8 7.49 0.56 1.1e-11 Mean corpuscular hemoglobin; TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg07092213 chr7:1199455 ZFAND2A -0.52 -6.0 -0.47 2.05e-8 Longevity;Endometriosis; TGCT cis rs4372836 0.504 rs13011935 chr2:29014746 C/T cg09522027 chr2:28974177 PPP1CB -0.56 -5.68 -0.45 9.2e-8 Body mass index; TGCT cis rs7119038 0.818 rs4936441 chr11:118725660 C/G cg19308663 chr11:118741387 NA -0.32 -5.98 -0.47 2.16e-8 Sjögren's syndrome; TGCT cis rs6500602 0.727 rs4786516 chr16:4578641 C/T cg08645402 chr16:4508243 NA 0.19 5.25 0.43 6.32e-7 Schizophrenia; TGCT cis rs12368653 0.557 rs903067 chr12:58011857 G/A cg12615879 chr12:58013172 SLC26A10 -0.5 -5.87 -0.47 3.81e-8 Multiple sclerosis; TGCT cis rs13256369 1.000 rs873064 chr8:8572380 G/A cg18904891 chr8:8559673 CLDN23 0.62 5.7 0.46 8.41e-8 Obesity-related traits; TGCT cis rs111803315 1.000 rs113097743 chr14:60018216 G/A cg22995959 chr14:59931024 GPR135 0.63 4.56 0.38 1.23e-5 Schizophrenia; TGCT trans rs1005277 0.579 rs2474567 chr10:38382492 C/T cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.13e-14 Extrinsic epigenetic age acceleration; TGCT cis rs9303401 0.659 rs7210432 chr17:56668170 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs416603 0.901 rs149597 chr16:11343942 C/G cg00044050 chr16:11439710 C16orf75 -0.82 -8.32 -0.6 1.31e-13 Type 1 diabetes; TGCT cis rs9308731 0.644 rs3789064 chr2:111915322 T/C cg04202892 chr2:111875749 ACOXL 0.55 6.48 0.5 1.98e-9 Chronic lymphocytic leukemia; TGCT cis rs3087591 0.959 rs2051505 chr17:29699859 C/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.22 -0.54 4.67e-11 Hip circumference; TGCT trans rs208520 0.802 rs1342959 chr6:66883329 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -10.21 -0.68 4.02e-18 Exhaled nitric oxide output; TGCT cis rs6088590 0.965 rs6088620 chr20:33412022 A/G cg06115741 chr20:33292138 TP53INP2 0.65 5.43 0.44 2.82e-7 Coronary artery disease; TGCT cis rs10883723 0.773 rs2296578 chr10:104240974 C/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12134245 0.747 rs17501512 chr1:92012481 C/G cg07090678 chr1:91966139 CDC7 -0.36 -4.83 -0.4 3.92e-6 Breast cancer; TGCT cis rs2836974 0.966 rs7283420 chr21:40666865 T/C cg17971929 chr21:40555470 PSMG1 0.93 8.98 0.63 3.63e-15 Cognitive function; TGCT cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs2290405 0.527 rs4690332 chr4:910520 C/T cg04824913 chr4:887549 GAK -0.37 -5.06 -0.41 1.45e-6 Systemic sclerosis; TGCT cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg20887711 chr4:1340912 KIAA1530 0.92 8.35 0.6 1.13e-13 Longevity; TGCT cis rs11190604 1.000 rs1800662 chr10:102289078 C/A cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1552244 0.572 rs6442154 chr3:10168785 A/G cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs2836974 0.583 rs8132993 chr21:40716410 T/C cg11644478 chr21:40555479 PSMG1 0.64 6.06 0.48 1.52e-8 Cognitive function; TGCT cis rs2932538 0.961 rs6537746 chr1:113163529 C/T cg22162597 chr1:113214053 CAPZA1 -0.27 -5.98 -0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7584330 0.868 rs7569197 chr2:238383073 A/G cg14458575 chr2:238380390 NA 0.5 7.89 0.58 1.35e-12 Prostate cancer; TGCT cis rs10791097 0.694 rs876641 chr11:130752040 A/C cg05962950 chr11:130786565 SNX19 0.91 11.68 0.72 1.01e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7552404 1.000 rs2133134 chr1:76179587 G/A cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6840360 1.000 rs9995704 chr4:152619069 C/A cg22705602 chr4:152727874 NA -0.25 -4.47 -0.37 1.71e-5 Intelligence (multi-trait analysis); TGCT cis rs11209002 0.524 rs2815386 chr1:67541996 A/G cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs7178424 0.742 rs12908081 chr15:62162264 C/T cg00456672 chr15:62358751 C2CD4A -0.31 -4.72 -0.39 6.37e-6 Height; TGCT cis rs11723530 0.538 rs12498436 chr4:170796457 C/G cg16551732 chr4:169799087 PALLD 0.34 4.54 0.38 1.34e-5 Myopia (pathological); TGCT trans rs1814175 0.645 rs28627251 chr11:50048125 G/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs6840360 0.593 rs11723227 chr4:152689717 G/A cg17479576 chr4:152424074 FAM160A1 -0.52 -5.2 -0.42 8.05e-7 Intelligence (multi-trait analysis); TGCT cis rs3749237 1.000 rs1317140 chr3:49878652 G/A cg07636037 chr3:49044803 WDR6 0.61 5.35 0.43 4.03e-7 Resting heart rate; TGCT cis rs1461503 0.548 rs7114175 chr11:122813983 A/T cg14473756 chr11:122847823 NA -0.47 -4.63 -0.38 8.99e-6 Menarche (age at onset); TGCT cis rs10479542 0.806 rs4700835 chr5:178976313 A/G cg00080972 chr5:178986291 RUFY1 0.44 5.06 0.41 1.45e-6 Lung cancer; TGCT cis rs2486012 0.649 rs246777 chr1:44274434 C/G cg12908607 chr1:44402522 ARTN -0.65 -5.46 -0.44 2.55e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg11644478 chr21:40555479 PSMG1 1.02 11.05 0.7 3.46e-20 Cognitive function; TGCT cis rs910316 1.000 rs175492 chr14:75545220 A/C cg08847533 chr14:75593920 NEK9 0.87 9.19 0.64 1.17e-15 Height; TGCT cis rs7666738 0.830 rs11727612 chr4:99001662 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9393692 0.645 rs11756673 chr6:26323505 A/G cg00631329 chr6:26305371 NA -0.46 -6.91 -0.53 2.23e-10 Educational attainment; TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs7017914 0.967 rs2639919 chr8:71875128 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.52 -4.84 -0.4 3.86e-6 Bone mineral density; TGCT cis rs13191362 1.000 rs13201023 chr6:162981381 C/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.87 0.4 3.38e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6840360 0.615 rs9996320 chr4:152610587 T/G cg22705602 chr4:152727874 NA -0.36 -5.97 -0.47 2.28e-8 Intelligence (multi-trait analysis); TGCT cis rs8177253 0.965 rs4854761 chr3:133498789 A/G cg01448562 chr3:133502909 NA 0.34 6.92 0.53 2.12e-10 Iron status biomarkers; TGCT cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs7267979 1.000 rs2500432 chr20:25290512 A/C cg03522245 chr20:25566470 NINL 0.62 6.71 0.52 6.12e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4455778 0.659 rs7792707 chr7:49059566 G/T cg26309511 chr7:48887640 NA 0.44 5.09 0.42 1.28e-6 Lung cancer in never smokers; TGCT cis rs5750830 0.649 rs5750820 chr22:39825322 T/G cg11247378 chr22:39784982 NA -0.73 -9.83 -0.66 3.22e-17 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs67614146 1 rs67614146 chr6:87821827 AC/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.41 -5.26 -0.43 6.16e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs453301 0.686 rs1045527 chr8:8890041 A/G cg06636001 chr8:8085503 FLJ10661 -0.65 -5.49 -0.44 2.18e-7 Joint mobility (Beighton score); TGCT trans rs7618501 0.669 rs3774758 chr3:49938227 C/G cg21659725 chr3:3221576 CRBN 0.78 9.49 0.65 2.23e-16 Intelligence (multi-trait analysis); TGCT cis rs4972806 0.849 rs1542180 chr2:177028767 C/T cg03152288 chr2:177042942 NA 0.59 5.24 0.43 6.67e-7 IgG glycosylation; TGCT cis rs6988636 1.000 rs16898097 chr8:124195034 G/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs4268898 0.722 rs11691212 chr2:24404733 A/G cg05570707 chr2:24270316 C2orf44 0.49 4.84 0.4 3.73e-6 Asthma; TGCT cis rs617219 0.737 rs12659709 chr5:78458257 C/G cg05890484 chr5:78407552 BHMT 0.38 5.25 0.43 6.28e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7731657 0.537 rs2189510 chr5:130316231 C/T cg08523029 chr5:130500466 HINT1 -0.57 -4.54 -0.38 1.33e-5 Fasting plasma glucose; TGCT cis rs35146811 0.735 rs1061230 chr7:99807265 G/A cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs7523273 0.597 rs66532523 chr1:207983745 A/C cg22525895 chr1:207977042 MIR29B2 -0.44 -6.29 -0.49 4.89e-9 Schizophrenia; TGCT cis rs9486719 1.000 rs9400016 chr6:96940883 G/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs11190604 1.000 rs2295772 chr10:102265183 G/A cg16342193 chr10:102329863 NA -0.38 -4.89 -0.4 3.06e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2549003 1.000 rs2549003 chr5:131829297 A/G cg00255919 chr5:131827918 IRF1 0.21 4.94 0.41 2.45e-6 Asthma (sex interaction); TGCT cis rs1971762 0.523 rs7135101 chr12:54080605 G/A cg16917193 chr12:54089295 NA 1.39 17.73 0.85 8.5000000000000007e-36 Height; TGCT cis rs72781680 1.000 rs7578969 chr2:24168620 T/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs9318086 0.712 rs3794339 chr13:24434065 A/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.79 8.29 0.6 1.6e-13 Myopia (pathological); TGCT cis rs713587 0.967 rs10182458 chr2:25150641 A/G cg01884057 chr2:25150051 NA 0.4 8.22 0.59 2.25e-13 Body mass index in non-asthmatics; TGCT cis rs2180341 0.814 rs6940933 chr6:127732740 C/G cg27446573 chr6:127587934 RNF146 0.87 7.91 0.58 1.21e-12 Breast cancer; TGCT cis rs853679 0.506 rs1150693 chr6:28174590 T/C cg12963246 chr6:28129442 ZNF389 0.49 4.85 0.4 3.65e-6 Depression; TGCT cis rs4237845 0.837 rs7954591 chr12:58299037 A/G cg02175503 chr12:58329896 NA 0.52 5.5 0.44 2.09e-7 Intelligence (multi-trait analysis); TGCT cis rs473651 0.935 rs520765 chr2:239354712 C/T cg08773314 chr2:239334832 ASB1 0.47 8.03 0.58 6.52e-13 Multiple system atrophy; TGCT cis rs858239 0.600 rs6461692 chr7:23139695 G/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.2 -0.42 7.92e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg08219700 chr8:58056026 NA 0.4 4.78 0.39 4.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs7613051 0.649 rs6777787 chr3:33057103 A/G cg19000631 chr3:33138515 GLB1;TMPPE 0.56 4.78 0.39 4.97e-6 Atopic dermatitis; TGCT cis rs7647973 0.593 rs1799844 chr3:49847642 G/A cg05785598 chr3:49045655 WDR6 -0.44 -5.15 -0.42 9.89e-7 Menarche (age at onset); TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg17178900 chr1:205818956 PM20D1 0.61 7.52 0.56 9.65e-12 Menarche (age at onset); TGCT cis rs12220238 0.730 rs10740421 chr10:75941002 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.07 0.54 9.74e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs75059851 1.000 rs73036065 chr11:133830067 G/T cg14047540 chr11:133829660 NA -0.52 -5.15 -0.42 1e-6 Schizophrenia; TGCT cis rs7103648 1.000 rs12292911 chr11:47449072 C/T cg20307385 chr11:47447363 PSMC3 1.05 13.23 0.76 1.9e-25 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs3540 0.597 rs12708583 chr15:91050271 C/T cg22089800 chr15:90895588 ZNF774 0.74 7.99 0.58 7.81e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs798554 0.679 rs13230995 chr7:2887284 G/A cg13628971 chr7:2884303 GNA12 0.54 4.64 0.38 8.74e-6 Height; TGCT cis rs10984561 0.881 rs12237206 chr9:122247803 C/G cg14242995 chr9:122249943 NA 0.75 6.41 0.5 2.7e-9 Pulmonary function decline; TGCT cis rs4988958 0.548 rs6543127 chr2:103028301 A/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs13242816 1.000 rs34652384 chr7:116157011 T/C cg16553024 chr7:116138462 CAV2 -0.45 -5.27 -0.43 5.81e-7 P wave duration; TGCT cis rs7666738 0.830 rs13147768 chr4:98833675 A/T cg17366294 chr4:99064904 C4orf37 0.72 7.47 0.56 1.23e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs853679 0.542 rs9393892 chr6:28081394 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs7267979 0.816 rs390123 chr20:25480105 C/G cg14121845 chr20:25566513 NINL 0.46 4.76 0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs7246657 0.722 rs2909098 chr19:38204248 G/A cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs12497850 0.931 rs10780033 chr3:48891275 T/C cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs6964587 1.000 rs4265 chr7:91719608 A/G cg22709100 chr7:91322751 NA -0.28 -4.8 -0.4 4.43e-6 Breast cancer; TGCT cis rs9486719 1.000 rs3798295 chr6:97052164 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs231513 0.681 rs75086002 chr17:42021918 C/T cg26893861 chr17:41843967 DUSP3 0.71 4.44 0.37 1.97e-5 Cognitive function; TGCT cis rs12950390 0.853 rs8078052 chr17:45859434 A/G cg06532163 chr17:45867833 NA 0.37 5.96 0.47 2.45e-8 IgG glycosylation; TGCT cis rs2354432 0.607 rs6677679 chr1:146803630 C/T cg25205988 chr1:146714368 CHD1L -1.41 -5.83 -0.46 4.57e-8 Mitochondrial DNA levels; TGCT cis rs78487399 0.808 rs7575024 chr2:43666991 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -4.83 -0.4 3.99e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7178424 0.875 rs28411984 chr15:62221592 A/C cg00456672 chr15:62358751 C2CD4A 0.31 4.5 0.37 1.57e-5 Height; TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg08736216 chr1:53307985 ZYG11A -0.31 -6.42 -0.5 2.63e-9 Monocyte count; TGCT cis rs1322512 0.959 rs2623985 chr6:152948748 T/C cg03415253 chr6:152958462 SYNE1 -0.56 -4.91 -0.4 2.8e-6 Tonometry; TGCT cis rs13088281 1.000 rs13088281 chr3:53147576 A/C cg07884673 chr3:53033167 SFMBT1 -0.6 -6.79 -0.52 4.2e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7937682 0.632 rs11608193 chr11:111732215 T/C cg09085632 chr11:111637200 PPP2R1B 0.81 7.14 0.54 6.97e-11 Primary sclerosing cholangitis; TGCT cis rs7769051 0.522 rs11965927 chr6:133101353 T/C cg07930552 chr6:133119739 C6orf192 1.21 4.81 0.4 4.24e-6 Type 2 diabetes nephropathy; TGCT cis rs12477438 0.520 rs4402818 chr2:99717608 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.17 0.82 2.46e-32 Chronic sinus infection; TGCT cis rs904251 0.828 rs1757174 chr6:37486695 G/A cg01843034 chr6:37503916 NA -0.52 -6.35 -0.5 3.64e-9 Cognitive performance; TGCT cis rs9325144 0.647 rs870431 chr12:38953073 T/C cg26384229 chr12:38710491 ALG10B -0.59 -5.6 -0.45 1.28e-7 Morning vs. evening chronotype; TGCT cis rs2180341 0.814 rs6919082 chr6:127737888 T/G cg24812749 chr6:127587940 RNF146 0.76 6.23 0.49 6.57e-9 Breast cancer; TGCT cis rs1371867 0.875 rs1660319 chr8:101337530 A/G cg06636551 chr8:101224915 SPAG1 -0.45 -6.12 -0.48 1.13e-8 Atrioventricular conduction; TGCT cis rs7769051 0.522 rs7738256 chr6:133113066 C/G cg07930552 chr6:133119739 C6orf192 1.33 5.16 0.42 9.59e-7 Type 2 diabetes nephropathy; TGCT cis rs2456568 0.709 rs1546400 chr11:93639203 G/A cg16099599 chr11:93583650 C11orf90 0.39 4.75 0.39 5.46e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2982552 0.815 rs3020349 chr6:152058268 C/A cg22157087 chr6:152012887 ESR1 0.2 4.89 0.4 3e-6 Bone properties (heel); TGCT trans rs2749592 0.531 rs1208559 chr10:38221370 T/C cg17830980 chr10:43048298 ZNF37B 0.67 7.08 0.54 9.67e-11 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs6570726 0.599 rs426371 chr6:145886469 A/G cg23711669 chr6:146136114 FBXO30 -0.71 -6.53 -0.51 1.56e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6988636 1.000 rs62521841 chr8:124194625 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs13177918 0.629 rs13161261 chr5:149822407 G/A cg14059543 chr5:149831962 NA -0.72 -9.49 -0.65 2.17e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs28374715 0.681 rs8037574 chr15:41630770 T/C cg18705301 chr15:41695430 NDUFAF1 -0.87 -13.45 -0.77 5.4e-26 Ulcerative colitis; TGCT cis rs60871478 0.636 rs4719520 chr7:875216 C/G cg15782153 chr7:917662 C7orf20 0.52 4.78 0.39 4.84e-6 Cerebrospinal P-tau181p levels; TGCT cis rs10465746 0.747 rs1952066 chr1:84436456 T/C cg10977910 chr1:84465055 TTLL7 0.69 7.04 0.53 1.14e-10 Obesity-related traits; TGCT cis rs459571 0.920 rs455073 chr9:136909141 G/C cg14405625 chr9:136855902 VAV2 -0.3 -4.44 -0.37 1.94e-5 Platelet distribution width; TGCT cis rs9650657 0.769 rs6601527 chr8:10665444 C/A cg27411982 chr8:10470053 RP1L1 -0.23 -5.32 -0.43 4.63e-7 Neuroticism; TGCT cis rs3008870 1.000 rs3008853 chr1:67385488 C/T cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs4805272 0.759 rs1030099 chr19:29343616 C/T cg15000279 chr19:29285009 NA 0.56 6.38 0.5 3.22e-9 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs3617 0.625 rs56019197 chr3:52874753 T/C cg11645453 chr3:52864694 ITIH4 -0.29 -5.58 -0.45 1.41e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2204008 0.748 rs11514352 chr12:38246954 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.42 0.55 1.6e-11 Bladder cancer; TGCT cis rs4820539 0.966 rs2267000 chr22:23455366 A/G cg21100191 chr22:23484243 RTDR1 0.93 11.4 0.72 4.8e-21 Bone mineral density; TGCT cis rs7412746 0.658 rs2275235 chr1:150730279 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.63 0.38 9.12e-6 Melanoma; TGCT trans rs3102947 0.929 rs3097276 chr2:8432132 A/G cg00548009 chr16:12637499 SNX29 0.34 6.68 0.51 7.02e-10 IgE levels; TGCT cis rs13082711 0.595 rs13075389 chr3:27339586 C/T cg02860705 chr3:27208620 NA 0.48 7.57 0.56 7.46e-12 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs986417 0.748 rs10136486 chr14:60946111 C/T cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs950169 0.650 rs12902052 chr15:85125838 A/T cg11189052 chr15:85197271 WDR73 0.78 6.44 0.5 2.42e-9 Schizophrenia; TGCT cis rs9486719 1.000 rs12208884 chr6:96885572 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs8067545 0.611 rs8071274 chr17:20216928 T/C cg13482628 chr17:19912719 NA -0.52 -4.45 -0.37 1.9e-5 Schizophrenia; TGCT cis rs9858542 0.953 rs9862080 chr3:49674458 A/G cg03060546 chr3:49711283 APEH -0.64 -5.7 -0.46 8.18e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2562456 0.755 rs2562421 chr19:21631304 T/G cg01304269 chr19:21688519 ZNF429 -0.61 -4.81 -0.4 4.22e-6 Pain; TGCT cis rs3780378 0.967 rs62543876 chr9:5085859 G/C cg03508284 chr9:4985524 JAK2 -0.48 -4.48 -0.37 1.68e-5 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs3820928 0.839 rs13398103 chr2:227859693 T/G cg11843606 chr2:227700838 RHBDD1 -0.54 -4.85 -0.4 3.62e-6 Pulmonary function; TGCT cis rs17473412 1.000 rs6880221 chr5:122739993 C/G cg15125798 chr5:122621645 NA -0.58 -5.14 -0.42 1.05e-6 Total body bone mineral density; TGCT cis rs3780378 0.875 rs4372063 chr9:5003338 C/T cg02405213 chr9:5042618 JAK2 -0.54 -6.68 -0.51 7.22e-10 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs10875746 0.669 rs17122812 chr12:48597053 A/G cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs7831492 0.564 rs7831530 chr8:41614567 G/A cg17182837 chr8:41585554 ANK1 -0.17 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs1018836 0.884 rs2073640 chr8:91594853 A/G cg16814680 chr8:91681699 NA -0.85 -9.12 -0.63 1.68e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.964 rs11765965 chr7:65842221 A/G cg18876405 chr7:65276391 NA 0.31 4.76 0.39 5.33e-6 Aortic root size; TGCT cis rs826838 0.967 rs11168299 chr12:38902028 G/T cg26384229 chr12:38710491 ALG10B 1.01 9.84 0.66 3.01e-17 Heart rate; TGCT cis rs6714710 0.603 rs2044459 chr2:98447004 T/C cg26665480 chr2:98280029 ACTR1B 0.66 6.27 0.49 5.45e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg10047753 chr17:41438598 NA 0.94 9.08 0.63 2.11e-15 Menopause (age at onset); TGCT cis rs11122272 0.667 rs2244992 chr1:231537220 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT cis rs9341808 0.718 rs9448886 chr6:80825901 C/T cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs9914988 0.943 rs1035989 chr17:27143810 T/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs56804039 0.573 rs11777722 chr8:8415295 T/C cg14215082 chr8:9055850 NA 0.5 4.9 0.4 2.91e-6 Cervical cancer; TGCT cis rs7772486 0.875 rs1960885 chr6:146325930 G/T cg23711669 chr6:146136114 FBXO30 0.84 9.12 0.63 1.72e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs1107366 0.618 rs1447657 chr3:125929471 A/G cg01346077 chr3:125931526 NA 0.39 6.38 0.5 3.26e-9 Metabolite levels; TGCT trans rs12339966 0.615 rs73642444 chr9:11337985 A/T cg03488587 chr11:64876988 C11orf2 0.32 7.0 0.53 1.42e-10 Systolic blood pressure; TGCT cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs76419734 0.510 rs6820671 chr4:106613821 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.71 4.66 0.39 7.95e-6 Post bronchodilator FEV1; TGCT cis rs4595586 0.525 rs6580891 chr12:39370127 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2692947 0.727 rs893173 chr2:96789787 T/C cg05933789 chr2:97190408 NA 0.15 4.53 0.38 1.37e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9364220 0.684 rs9355053 chr6:168493061 G/C cg02770688 chr6:168491649 NA -0.3 -5.52 -0.44 1.92e-7 Attention deficit hyperactivity disorder (inattention symptoms);Attention deficit hyperactivity disorder (combined symptoms); TGCT cis rs6484504 0.576 rs208090 chr11:31190992 T/C cg26647111 chr11:31128758 NA -0.34 -4.63 -0.38 9.09e-6 Red blood cell count; TGCT cis rs8017423 0.967 rs2277517 chr14:90722778 G/A cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs6952808 0.792 rs35582663 chr7:1948756 G/A cg22963979 chr7:1858916 MAD1L1 -0.35 -5.43 -0.44 2.9e-7 Bipolar disorder and schizophrenia; TGCT cis rs7666738 0.830 rs890470 chr4:98923435 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs7975161 0.520 rs4502051 chr12:104695569 A/T cg25273343 chr12:104657179 TXNRD1 -0.36 -5.0 -0.41 1.9e-6 Toenail selenium levels; TGCT cis rs7178572 0.539 rs12594346 chr15:77671966 A/T cg15453836 chr15:77711506 NA 0.43 4.77 0.39 5.1e-6 Type 2 diabetes; TGCT cis rs13394619 0.936 rs9789414 chr2:11724684 A/G cg07314298 chr2:11723111 GREB1 -0.29 -5.16 -0.42 9.68e-7 Endometriosis; TGCT cis rs2933343 1.000 rs2630252 chr3:128624772 T/C cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg27588902 chr6:42928151 GNMT -0.49 -5.93 -0.47 2.85e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs548181 0.611 rs2849225 chr11:125415936 A/G cg03464685 chr11:125439445 EI24 1.65 11.17 0.71 1.79e-20 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10883723 0.810 rs7912901 chr10:104277440 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7226408 0.857 rs72887045 chr18:34481737 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1395 0.778 rs72810794 chr2:27401260 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.65 9.03 0.63 2.73e-15 Blood metabolite levels; TGCT cis rs7267979 1.000 rs3002702 chr20:25268920 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs2688482 0.512 rs1104760 chr3:195517321 G/A cg17952111 chr19:54960355 LENG8 0.83 6.82 0.52 3.57e-10 Lung disease severity in cystic fibrosis; TGCT cis rs2730260 0.537 rs73169248 chr7:158891742 T/G cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs2836950 0.501 rs62223052 chr21:40708702 A/C cg17971929 chr21:40555470 PSMG1 -0.52 -4.51 -0.38 1.46e-5 Menarche (age at onset); TGCT cis rs11696501 0.739 rs6073835 chr20:44286454 C/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.55 -0.38 1.29e-5 Brain structure; TGCT cis rs362296 0.590 rs4690081 chr4:3262105 T/G cg06533319 chr4:3265114 C4orf44 0.24 4.71 0.39 6.61e-6 Parental longevity (mother's age at death); TGCT trans rs6040399 1.000 rs6040398 chr20:11156550 C/T cg11320084 chr1:185014181 RNF2 0.34 6.65 0.51 8.45e-10 Response to citalopram treatment; TGCT cis rs786425 0.585 rs10744162 chr12:124243707 T/C cg10461218 chr12:124144432 GTF2H3 0.22 4.67 0.39 7.73e-6 Pubertal anthropometrics; TGCT cis rs6088580 0.634 rs6141465 chr20:32967314 T/C cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs739401 0.611 rs494427 chr11:3048140 A/G cg25174290 chr11:3078921 CARS 0.48 4.68 0.39 7.48e-6 Longevity; TGCT cis rs6840360 0.642 rs7666571 chr4:152443273 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs4253772 0.591 rs6520010 chr22:46721223 G/A cg26492175 chr22:47022658 GRAMD4 0.19 4.5 0.37 1.54e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs4722166 0.573 rs35436671 chr7:22775508 G/A cg13104385 chr7:22767384 IL6 0.22 4.64 0.38 8.6e-6 Lung cancer; TGCT cis rs4629710 0.592 rs11154622 chr6:131547578 C/T cg12606694 chr6:131520996 AKAP7 0.39 4.63 0.38 9.14e-6 Multiple myeloma (IgH translocation); TGCT cis rs1997103 1.000 rs6958664 chr7:55404958 T/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1475911 1.000 rs2839465 chr21:43511232 C/T cg14562523 chr21:43528734 C21orf128;UMODL1 -0.23 -4.75 -0.39 5.58e-6 IgG glycosylation; TGCT cis rs7568458 0.591 rs55971080 chr2:85812746 T/C cg17127132 chr2:85788382 GGCX 0.69 6.25 0.49 5.98e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9303401 0.659 rs2072316 chr17:56604813 G/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs3806843 0.576 rs251368 chr5:140241027 G/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.41 4.82 0.4 4.07e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6840360 0.642 rs7698816 chr4:152352972 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs453301 0.598 rs1025395 chr8:8836603 G/C cg15556689 chr8:8085844 FLJ10661 0.78 6.92 0.53 2.12e-10 Joint mobility (Beighton score); TGCT cis rs9911578 1.000 rs999431 chr17:56854441 A/G cg05425664 chr17:57184151 TRIM37 -0.61 -5.98 -0.47 2.24e-8 Intelligence (multi-trait analysis); TGCT cis rs2576037 0.583 rs9916891 chr18:44493521 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.66 -0.39 7.96e-6 Personality dimensions; TGCT cis rs10883723 0.810 rs2281879 chr10:104268877 C/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.8 -0.4 4.57e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6121246 0.567 rs2811 chr20:30194248 A/G cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs17767294 0.614 rs41269285 chr6:28194799 T/C cg08851530 chr6:28072375 NA 1.46 6.76 0.52 4.79e-10 Parkinson's disease; TGCT cis rs10986311 0.802 rs1330811 chr9:127117346 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.75 0.39 5.63e-6 Vitiligo; TGCT cis rs801193 1.000 rs1553609 chr7:66197139 T/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs1401999 0.510 rs2293001 chr3:183700211 C/T cg01324343 chr3:183735012 ABCC5 0.52 5.66 0.45 9.97e-8 Anterior chamber depth; TGCT cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg06481639 chr22:41940642 POLR3H -0.71 -6.26 -0.49 5.75e-9 Vitiligo; TGCT cis rs17401966 0.558 rs4846218 chr1:10452040 G/T cg19773385 chr1:10388646 KIF1B -0.22 -5.05 -0.41 1.56e-6 Hepatocellular carcinoma; TGCT cis rs4819052 0.851 rs35560973 chr21:46662573 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.74 0.39 5.74e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1153858 1.000 rs67461176 chr15:45676819 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs35160687 0.871 rs2278105 chr2:86466516 A/G cg17168863 chr2:85470620 TCF7L1 0.27 4.44 0.37 1.99e-5 Night sleep phenotypes; TGCT cis rs68170813 0.521 rs75035695 chr7:106818731 T/C cg02696742 chr7:106810147 HBP1 -0.7 -6.05 -0.48 1.59e-8 Coronary artery disease; TGCT cis rs35306767 0.807 rs34527494 chr10:935192 T/C cg26597838 chr10:835615 NA 0.81 12.42 0.74 1.61e-23 Eosinophil percentage of granulocytes; TGCT cis rs651907 0.557 rs17347644 chr3:101547733 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.89 0.4 3e-6 Colorectal cancer; TGCT cis rs13191362 1.000 rs35017019 chr6:162982581 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4478858 0.735 rs4949205 chr1:31800579 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg17345569 chr6:42928274 GNMT -0.47 -4.94 -0.41 2.49e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg03188948 chr7:1209495 NA 0.64 5.76 0.46 6.34e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1801251 0.893 rs11687128 chr2:233608901 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs2455799 0.559 rs1447652 chr3:15907128 G/C cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs7681440 0.904 rs2301135 chr4:90758389 G/C cg20003494 chr4:90757398 SNCA -0.61 -5.78 -0.46 5.59e-8 Dementia with Lewy bodies; TGCT cis rs2050392 0.767 rs10763786 chr10:30693567 G/C cg18806716 chr10:30721971 MAP3K8 0.67 8.98 0.63 3.71e-15 Inflammatory bowel disease; TGCT cis rs1371867 0.875 rs1125706 chr8:101326739 T/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs17387100 1.000 rs17387100 chr4:15995125 A/G cg13480465 chr4:16795757 LDB2 -0.41 -4.66 -0.39 8e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs28595532 0.920 rs17324821 chr4:119770716 A/G cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT trans rs783396 0.685 rs3804344 chr6:107087870 G/A cg27564810 chr2:201635376 AOX2P 0.5 6.61 0.51 1e-9 Stroke; TGCT cis rs1218582 0.774 rs11264284 chr1:154875793 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.65 -6.51 -0.5 1.68e-9 Prostate cancer; TGCT trans rs208520 0.690 rs207740 chr6:66764132 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.29 0.71 9.4e-21 Exhaled nitric oxide output; TGCT cis rs7119 0.717 rs12902896 chr15:77809150 G/T cg27398640 chr15:77910606 LINGO1 0.25 4.59 0.38 1.06e-5 Type 2 diabetes; TGCT cis rs9326248 0.520 rs74830 chr11:117090558 C/T cg01368799 chr11:117014884 PAFAH1B2 -0.58 -5.3 -0.43 5.01e-7 Blood protein levels; TGCT cis rs11122272 0.732 rs2808605 chr1:231540187 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs7568458 0.660 rs6722691 chr2:85758352 C/T cg02493740 chr2:85810744 VAMP5 -0.29 -5.7 -0.46 8.09e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7659604 1.000 rs28433617 chr4:122664138 C/A cg19748678 chr4:122722346 EXOSC9 0.57 5.54 0.45 1.69e-7 Type 2 diabetes; TGCT cis rs4836694 0.574 rs3824542 chr9:132936132 C/T cg05251000 chr9:132935664 FREQ 0.52 5.53 0.44 1.79e-7 Alzheimer's disease (cognitive decline); TGCT cis rs12484776 0.786 rs17323619 chr22:40538717 C/G cg07138101 chr22:40742427 ADSL -0.61 -4.69 -0.39 7.22e-6 Uterine fibroids; TGCT cis rs9640161 0.636 rs3735171 chr7:150033882 A/G cg17279839 chr7:150038598 RARRES2 0.44 4.65 0.39 8.35e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs1552244 0.882 rs7636817 chr3:10014876 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.49 0.44 2.21e-7 Alzheimer's disease; TGCT cis rs1997103 0.954 rs6953004 chr7:55411919 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg08439880 chr3:133502540 NA -0.29 -5.42 -0.44 2.93e-7 Iron status biomarkers; TGCT cis rs7267979 0.966 rs8123949 chr20:25388133 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6912958 0.874 rs2103764 chr6:88157392 T/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.22 -0.49 7.06e-9 Monocyte percentage of white cells; TGCT cis rs6088580 0.634 rs6120642 chr20:33012531 A/G cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs453301 0.512 rs2921381 chr8:8895401 T/A cg15556689 chr8:8085844 FLJ10661 0.78 7.2 0.54 5.07e-11 Joint mobility (Beighton score); TGCT cis rs9303401 0.573 rs34097494 chr17:57171917 C/T cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs4819052 0.819 rs7279136 chr21:46692287 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12479064 0.724 rs2305352 chr2:100015124 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.73 -6.44 -0.5 2.42e-9 Chronic sinus infection; TGCT cis rs6860806 0.507 rs272883 chr5:131668698 A/G cg24060327 chr5:131705240 SLC22A5 -0.76 -8.4 -0.6 8.54e-14 Breast cancer; TGCT cis rs6570726 0.791 rs9399558 chr6:145911730 T/C cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3008870 0.883 rs2755249 chr1:67493662 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.4 0.72 5.07e-21 Lymphocyte percentage of white cells; TGCT cis rs5750830 0.649 rs5750820 chr22:39825322 T/G cg01416388 chr22:39784598 NA -0.7 -6.92 -0.53 2.11e-10 Intelligence (multi-trait analysis); TGCT cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg08392591 chr16:89556376 ANKRD11 0.6 5.72 0.46 7.47e-8 Multiple myeloma (IgH translocation); TGCT cis rs12188164 1.000 rs56042615 chr5:437667 G/A cg21144161 chr5:423903 AHRR 0.26 4.94 0.41 2.49e-6 Cystic fibrosis severity; TGCT cis rs6545883 0.868 rs2441381 chr2:61798829 C/T cg15711740 chr2:61764176 XPO1 -0.6 -5.66 -0.45 1e-7 Tuberculosis; TGCT cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.65 0.39 8.34e-6 Renal cell carcinoma; TGCT cis rs79349575 0.783 rs4399576 chr17:47009835 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs4665809 1.000 rs4665817 chr2:26305167 G/A cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs1519814 0.915 rs10808507 chr8:121166429 G/A cg22335954 chr8:121166405 COL14A1 -0.32 -4.59 -0.38 1.09e-5 Breast cancer; TGCT cis rs7666738 0.791 rs1967978 chr4:98966152 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.861 rs28821920 chr4:98962743 T/C cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs56235845 0.964 rs4075958 chr5:176784512 A/G cg16006841 chr5:176797999 RGS14 -0.7 -12.16 -0.74 7.1e-23 Hemoglobin concentration;Hematocrit; TGCT cis rs1018836 0.651 rs2339175 chr8:91565805 A/T cg16814680 chr8:91681699 NA -0.87 -9.27 -0.64 7.48e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg11644478 chr21:40555479 PSMG1 1.04 10.72 0.69 2.25e-19 Cognitive function; TGCT cis rs651907 0.557 rs7651721 chr3:101393583 C/A cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs7552404 1.000 rs2133134 chr1:76179587 G/A cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg02953382 chr22:24373134 LOC391322 0.86 10.12 0.67 6.61e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2276314 1.000 rs2298715 chr18:33552425 T/C cg19628046 chr18:33552617 C18orf21 0.53 4.5 0.37 1.53e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs637571 0.522 rs550435 chr11:65732651 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.6 6.03 0.48 1.75e-8 Eosinophil percentage of white cells; TGCT cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT trans rs1005277 0.579 rs2749616 chr10:38510993 A/T cg17830980 chr10:43048298 ZNF37B -0.82 -10.26 -0.68 2.99e-18 Extrinsic epigenetic age acceleration; TGCT cis rs4891159 0.548 rs609487 chr18:74134382 C/G cg24786174 chr18:74118243 ZNF516 -0.66 -13.52 -0.77 3.66e-26 Longevity; TGCT cis rs2235642 0.691 rs2281235 chr16:1603535 T/C cg07341220 chr16:1583899 IFT140;TMEM204 -0.29 -4.56 -0.38 1.23e-5 Coronary artery disease; TGCT cis rs6463523 0.898 rs66892628 chr7:759374 T/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.94 11.59 0.72 1.71e-21 Subjective well-being; TGCT cis rs10838634 0.901 rs16938534 chr11:46887384 T/C cg18332754 chr11:46939436 LRP4 0.89 4.77 0.39 5.13e-6 Schizophrenia; TGCT cis rs7714584 1.000 rs7724036 chr5:150284808 A/G cg22134413 chr5:150180641 NA -0.71 -5.67 -0.45 9.7e-8 Crohn's disease; TGCT cis rs11112613 0.762 rs66754070 chr12:105949779 G/A cg03607813 chr12:105948248 NA 0.52 6.0 0.47 2.03e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs617219 0.591 rs1840805 chr5:78565563 T/A cg05890484 chr5:78407552 BHMT -0.36 -4.86 -0.4 3.5e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs3812831 0.695 rs7998546 chr13:114939914 C/G cg08824895 chr13:115047677 UPF3A 0.48 4.75 0.39 5.59e-6 Schizophrenia; TGCT cis rs875971 1.000 rs4718343 chr7:65874288 T/G cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs1372520 0.684 rs356188 chr4:90691537 T/C cg01966878 chr4:90757139 SNCA 0.3 4.82 0.4 4.11e-6 Neuroticism; TGCT cis rs2204008 0.715 rs11525003 chr12:38332359 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg26531700 chr6:26746687 NA 0.51 4.71 0.39 6.4e-6 Intelligence (multi-trait analysis); TGCT cis rs9467711 1.000 rs6908156 chr6:26322861 C/T cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs4851266 1.000 rs4851264 chr2:100810188 T/C cg07810366 chr2:100720526 AFF3 -0.39 -5.62 -0.45 1.2e-7 Educational attainment; TGCT cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg23205692 chr1:25664452 TMEM50A -0.47 -4.97 -0.41 2.22e-6 Erythrocyte sedimentation rate; TGCT cis rs74233809 1.000 rs10883832 chr10:104871279 T/G cg05855489 chr10:104503620 C10orf26 0.84 4.47 0.37 1.71e-5 Birth weight; TGCT cis rs13256369 1.000 rs13282915 chr8:8570891 T/G cg06671706 chr8:8559999 CLDN23 0.34 4.57 0.38 1.18e-5 Obesity-related traits; TGCT cis rs4891159 0.526 rs2848961 chr18:74129886 C/G cg24786174 chr18:74118243 ZNF516 -0.67 -12.97 -0.76 7.68e-25 Longevity; TGCT cis rs11190604 0.767 rs10883481 chr10:102165021 G/A cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.5e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs1362404 0.648 rs4784888 chr16:51969082 C/T cg03955530 chr16:52681474 NA 0.29 4.64 0.38 8.61e-6 Gut microbiota (bacterial taxa); TGCT cis rs2439831 0.850 rs56909447 chr15:44137618 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs78487399 0.808 rs6761129 chr2:43735713 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.53 -0.44 1.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs858239 0.899 rs1881203 chr7:23292808 T/C cg05602783 chr7:23145260 KLHL7 -0.6 -4.77 -0.39 5.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs13242816 1.000 rs3807987 chr7:116179834 G/A cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg01448562 chr3:133502909 NA -0.26 -5.06 -0.41 1.49e-6 Iron status biomarkers; TGCT cis rs9818758 0.607 rs73084135 chr3:49272218 A/G cg00383909 chr3:49044727 WDR6 1.31 6.76 0.52 4.72e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6831352 0.918 rs29001195 chr4:100054244 G/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 7.0 0.53 1.44e-10 Platelet count; TGCT cis rs72634258 0.554 rs34305100 chr1:7913029 A/G cg26816564 chr1:7831052 VAMP3 0.64 4.88 0.4 3.16e-6 Inflammatory bowel disease; TGCT cis rs3008870 0.755 rs2815363 chr1:67497221 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.8 -8.48 -0.61 5.61e-14 Lymphocyte percentage of white cells; TGCT cis rs11175492 0.528 rs11175479 chr12:65027421 A/G cg18624581 chr12:65153313 GNS -0.85 -4.64 -0.38 8.76e-6 Platelet count; TGCT cis rs3733585 0.648 rs67820465 chr4:9975873 A/G cg00071950 chr4:10020882 SLC2A9 -0.57 -6.62 -0.51 9.8e-10 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs6089829 0.926 rs7273917 chr20:61665975 G/A cg23505145 chr19:12996616 KLF1 0.8 8.19 0.59 2.76e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs986417 1.000 rs1254265 chr14:60840478 T/C cg27398547 chr14:60952738 C14orf39 -1.36 -8.75 -0.62 1.28e-14 Gut microbiota (bacterial taxa); TGCT cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg10935138 chr17:73851978 WBP2 1.01 6.59 0.51 1.12e-9 Psoriasis; TGCT cis rs1552244 0.554 rs3732965 chr3:10048760 A/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs10992471 0.603 rs10116813 chr9:95090360 C/T cg14631576 chr9:95140430 CENPP -0.32 -4.71 -0.39 6.43e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs860554 0.921 rs1779300 chr1:201261666 G/A cg01022117 chr1:201258280 PKP1 0.33 5.26 0.43 6.12e-7 Panic disorder; TGCT cis rs7178572 0.568 rs12908262 chr15:77493256 G/A cg22256960 chr15:77711686 NA -0.88 -8.99 -0.63 3.53e-15 Type 2 diabetes; TGCT cis rs36051895 0.632 rs62543560 chr9:5175938 C/T cg02405213 chr9:5042618 JAK2 -0.71 -9.57 -0.65 1.42e-16 Pediatric autoimmune diseases; TGCT cis rs4746818 0.579 rs118014923 chr10:70932108 T/C cg11621586 chr10:70884670 VPS26A -1.23 -5.0 -0.41 1.94e-6 Left atrial antero-posterior diameter; TGCT cis rs11031096 0.542 rs10835337 chr11:3958828 A/G cg18678763 chr11:4115507 RRM1 0.42 5.14 0.42 1.05e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7959452 0.590 rs11177643 chr12:69785712 T/G cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs4253772 0.550 rs6007823 chr22:46706249 C/T cg24881330 chr22:46731750 TRMU 1.01 5.42 0.44 3.03e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs6504950 0.566 rs7208403 chr17:53046667 C/A cg19360675 chr17:53046073 COX11;STXBP4 0.56 5.46 0.44 2.48e-7 Breast cancer; TGCT trans rs7819412 0.775 rs11773990 chr8:10935082 T/C cg15556689 chr8:8085844 FLJ10661 -0.84 -8.16 -0.59 3.12e-13 Triglycerides; TGCT cis rs13392177 0.647 rs10932761 chr2:219064391 T/A cg00012203 chr2:219082015 ARPC2 -0.81 -8.14 -0.59 3.48e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs11574514 1.000 rs117017165 chr16:67646311 G/A cg00545966 chr16:67701244 C16orf86;C16orf48 0.72 4.45 0.37 1.87e-5 Crohn's disease; TGCT cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg17971929 chr21:40555470 PSMG1 -0.96 -9.39 -0.64 3.88e-16 Cognitive function; TGCT cis rs769267 0.965 rs2074303 chr19:19381755 C/T cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs2070488 0.965 rs1065800 chr3:38566480 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.19 -0.59 2.71e-13 Electrocardiographic conduction measures; TGCT cis rs56104184 0.779 rs17206686 chr19:49356317 A/G cg15549821 chr19:49342101 PLEKHA4 -0.79 -9.39 -0.64 3.75e-16 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7588654 0.793 rs16859517 chr2:219949184 A/G cg06736663 chr2:219754761 WNT10A 0.48 4.79 0.39 4.72e-6 Height; TGCT cis rs9291683 0.588 rs13133766 chr4:10019732 C/T cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Bone mineral density; TGCT trans rs7088591 0.702 rs10491208 chr10:59703352 C/G cg02584432 chr5:138740366 SPATA24 0.71 6.78 0.52 4.3e-10 Blood pressure; TGCT cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg03060546 chr3:49711283 APEH 0.51 4.91 0.4 2.84e-6 Menarche (age at onset); TGCT cis rs9303401 0.527 rs7224468 chr17:56749943 C/T cg25039879 chr17:56429692 SUPT4H1 0.53 4.55 0.38 1.25e-5 Cognitive test performance; TGCT cis rs35883536 0.647 rs34195036 chr1:101040429 C/A cg10298815 chr1:101004474 GPR88 -0.24 -4.51 -0.38 1.47e-5 Monocyte count; TGCT cis rs9796 0.870 rs1001341 chr15:41261491 T/A cg18705301 chr15:41695430 NDUFAF1 0.43 5.63 0.45 1.13e-7 Menopause (age at onset); TGCT cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg06481639 chr22:41940642 POLR3H -0.71 -6.39 -0.5 3.11e-9 Vitiligo; TGCT cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg18654377 chr3:49208889 KLHDC8B -0.38 -5.03 -0.41 1.69e-6 Menarche (age at onset); TGCT cis rs7560180 1 rs7560180 chr2:113965200 A/T cg27425262 chr2:113953981 PSD4;LOC440839 0.4 4.67 0.39 7.79e-6 Hemoglobin concentration; TGCT cis rs7089973 0.604 rs11196941 chr10:116596258 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9611565 0.694 rs5758411 chr22:42079734 G/A cg17554472 chr22:41940697 POLR3H 0.47 5.02 0.41 1.72e-6 Vitiligo; TGCT cis rs7666738 0.927 rs6832373 chr4:99051967 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.24 0.43 6.54e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.851 rs1999334 chr21:46670457 A/G cg06618935 chr21:46677482 NA -0.32 -4.98 -0.41 2.06e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs17076896 0.786 rs74570351 chr13:19933722 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs13191362 1.000 rs34192365 chr6:163012382 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2204008 0.665 rs11179830 chr12:38220966 T/C cg13010199 chr12:38710504 ALG10B 0.58 4.59 0.38 1.08e-5 Bladder cancer; TGCT cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg21724239 chr8:58056113 NA 0.39 4.59 0.38 1.07e-5 Developmental language disorder (linguistic errors); TGCT cis rs10883723 0.810 rs1409311 chr10:104282160 G/A cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs2839186 0.934 rs13046494 chr21:47707430 A/C cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs6854137 0.904 rs13124822 chr4:169737712 G/A cg20607169 chr4:169750834 PALLD 0.21 4.56 0.38 1.23e-5 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs208520 0.909 rs9453672 chr6:66991431 A/G cg07460842 chr6:66804631 NA 0.74 6.46 0.5 2.11e-9 Exhaled nitric oxide output; TGCT cis rs9633740 0.578 rs11185982 chr10:82305627 C/T cg01528321 chr10:82214614 TSPAN14 1.09 6.58 0.51 1.19e-9 Post bronchodilator FEV1; TGCT cis rs6752107 0.967 rs2880080 chr2:234154139 G/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.98 0.41 2.06e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.798 rs1453562 chr2:99615850 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs875971 1.000 rs6961990 chr7:65888570 C/A cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs4654899 0.802 rs2290381 chr1:21213271 C/A cg01072550 chr1:21505969 NA -0.47 -7.05 -0.53 1.11e-10 Superior frontal gyrus grey matter volume; TGCT cis rs2153535 0.580 rs6597326 chr6:8482019 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.5 4.78 0.39 4.89e-6 Blood metabolite levels; TGCT cis rs10791097 0.694 rs7107595 chr11:130758556 C/T cg14779329 chr11:130786720 SNX19 0.28 4.95 0.41 2.36e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6901250 0.851 rs7760125 chr6:117123391 A/C cg12892004 chr6:117198278 RFX6 0.54 6.6 0.51 1.05e-9 C-reactive protein levels; TGCT cis rs6951245 0.580 rs10257426 chr7:1213694 G/A cg03188948 chr7:1209495 NA 0.7 6.19 0.49 8.06e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2651899 0.902 rs1736522 chr1:3080940 C/G cg07622451 chr1:3079886 PRDM16 0.25 4.87 0.4 3.36e-6 Migraine; TGCT cis rs8017423 0.934 rs11159952 chr14:90684874 T/C cg04374321 chr14:90722782 PSMC1 0.77 7.93 0.58 1.12e-12 Mortality in heart failure; TGCT cis rs1008375 1.000 rs4698200 chr4:17657051 G/A cg16339924 chr4:17578868 LAP3 0.61 5.19 0.42 8.41e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs644799 0.648 rs1255176 chr11:95471465 A/T cg03916912 chr11:95522834 CEP57;FAM76B 0.51 5.17 0.42 9.05e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2050392 0.792 rs684395 chr10:30719112 C/G cg18806716 chr10:30721971 MAP3K8 -0.48 -5.52 -0.44 1.94e-7 Inflammatory bowel disease; TGCT cis rs2797160 0.547 rs9388442 chr6:125972608 G/C cg05901451 chr6:126070800 HEY2 -0.63 -5.35 -0.43 4.14e-7 Endometrial cancer; TGCT cis rs4478858 0.698 rs4949204 chr1:31800415 A/G cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs4975709 0.569 rs4975743 chr5:1859941 G/T cg15595755 chr5:1867978 NA 0.45 5.13 0.42 1.08e-6 Cardiovascular disease risk factors; TGCT cis rs377070 0.816 rs309404 chr4:123617741 A/T cg10495464 chr4:123653540 BBS12;LOC729338 -0.42 -4.72 -0.39 6.35e-6 Mosquito bite size; TGCT cis rs12541335 0.639 rs35068739 chr8:22201719 T/C cg09517075 chr8:22133004 PIWIL2 0.25 4.95 0.41 2.36e-6 Hypertriglyceridemia; TGCT cis rs597539 0.652 rs559032 chr11:68710847 G/T cg06028808 chr11:68637592 NA 0.54 7.03 0.53 1.2e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg27535305 chr1:53392650 SCP2 -0.23 -4.6 -0.38 1.03e-5 Monocyte count; TGCT cis rs11264213 0.591 rs274732 chr1:36488199 T/G cg27506609 chr1:36549197 TEKT2 -0.47 -5.33 -0.43 4.54e-7 Schizophrenia; TGCT cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg13395646 chr4:1353034 KIAA1530 -0.38 -4.72 -0.39 6.28e-6 Obesity-related traits; TGCT cis rs11690935 0.843 rs9784070 chr2:172785007 C/T cg13550731 chr2:172543902 DYNC1I2 -0.89 -7.98 -0.58 8.45e-13 Schizophrenia; TGCT cis rs9427116 0.531 rs35504625 chr1:154599778 C/G cg17218026 chr1:154582156 ADAR 0.31 7.77 0.57 2.51e-12 Blood protein levels; TGCT cis rs12780845 0.540 rs2295809 chr10:17199871 A/T cg01003015 chr10:17271136 VIM -0.52 -4.71 -0.39 6.42e-6 Homocysteine levels; TGCT cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg10117171 chr1:25599238 RHD -0.36 -5.87 -0.47 3.8e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs10927875 0.541 rs1739844 chr1:16343322 T/C cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs3812831 0.669 rs382913 chr13:114928255 G/T cg08824895 chr13:115047677 UPF3A 0.49 4.73 0.39 5.98e-6 Schizophrenia; TGCT cis rs9457247 1.000 rs422094 chr6:167397033 C/G cg25258033 chr6:167368657 RNASET2 0.18 4.52 0.38 1.42e-5 Crohn's disease; TGCT cis rs3749237 0.595 rs3870338 chr3:49557051 A/G cg07636037 chr3:49044803 WDR6 0.61 5.79 0.46 5.4e-8 Resting heart rate; TGCT cis rs11252926 0.599 rs11252213 chr10:454694 C/T cg20256804 chr10:444983 DIP2C -0.22 -4.73 -0.39 6.02e-6 Psychosis in Alzheimer's disease; TGCT cis rs12477438 0.765 rs6754843 chr2:99680485 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs12477438 0.798 rs6542848 chr2:99573732 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.7 -6.22 -0.49 7.15e-9 Chronic sinus infection; TGCT cis rs9916302 0.861 rs4795377 chr17:37669056 C/T cg15445000 chr17:37608096 MED1 0.32 4.66 0.39 8.18e-6 Glomerular filtration rate (creatinine); TGCT cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.22 -0.42 7.39e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs34070283 chr4:98893027 A/T cg18180107 chr4:99064573 C4orf37 0.53 4.84 0.4 3.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6964587 0.967 rs6973896 chr7:91778465 A/G cg17063962 chr7:91808500 NA 0.93 10.08 0.67 8.03e-18 Breast cancer; TGCT cis rs2224391 0.628 rs6913120 chr6:5260505 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.03 -6.43 -0.5 2.47e-9 Height; TGCT cis rs6987853 0.933 rs2974339 chr8:42397529 T/C cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs611744 0.967 rs591792 chr8:109200446 T/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs7568458 0.870 rs6757263 chr2:85803542 A/G cg17127132 chr2:85788382 GGCX 0.72 6.7 0.52 6.53e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs861020 0.630 rs628300 chr1:209998298 C/T cg05527609 chr1:210001259 C1orf107 0.9 7.9 0.58 1.31e-12 Orofacial clefts; TGCT cis rs739496 0.615 rs1544396 chr12:112062875 C/T cg10833066 chr12:111807467 FAM109A -0.35 -5.01 -0.41 1.86e-6 Platelet count; TGCT cis rs9916302 0.904 rs7501488 chr17:37576417 T/G cg07936489 chr17:37558343 FBXL20 -0.65 -4.98 -0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs35865860 chr4:98968822 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7539409 0.651 rs6576953 chr1:84316946 A/G cg10977910 chr1:84465055 TTLL7 0.88 5.62 0.45 1.19e-7 Alzheimer's disease; TGCT cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg00149659 chr3:10157352 C3orf10 -0.96 -6.1 -0.48 1.26e-8 Alzheimer's disease; TGCT cis rs2204008 0.682 rs2320517 chr12:38259239 A/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs6840360 0.554 rs4643789 chr4:152726691 C/T cg17479576 chr4:152424074 FAM160A1 -0.49 -5.08 -0.42 1.33e-6 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.24e-9 Blood metabolite levels; TGCT cis rs7258465 1.000 rs4808134 chr19:18608579 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs7772486 0.875 rs865913 chr6:146308874 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.5 0.65 2.02e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4253772 0.591 rs6007795 chr22:46686792 C/G cg24881330 chr22:46731750 TRMU 0.96 6.38 0.5 3.18e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs854765 0.693 rs4924822 chr17:17748013 A/G cg09796270 chr17:17721594 SREBF1 -0.25 -4.55 -0.38 1.28e-5 Total body bone mineral density; TGCT cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg19318889 chr4:1322082 MAEA 0.19 4.51 0.38 1.46e-5 Longevity; TGCT cis rs2153535 0.580 rs718502 chr6:8527400 T/C cg07606381 chr6:8435919 SLC35B3 0.53 4.97 0.41 2.22e-6 Motion sickness; TGCT cis rs4665809 1.000 rs10202478 chr2:26276049 T/C cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 1.99e-6 Gut microbiome composition (summer); TGCT cis rs4148883 0.689 rs1311621 chr4:100014018 T/C cg13256891 chr4:100009986 ADH5 0.42 4.49 0.37 1.64e-5 Alcohol dependence; TGCT cis rs28595532 0.702 rs72670250 chr4:119337134 T/C cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg17054783 chr10:134559939 INPP5A 0.23 4.64 0.38 8.89e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg08859206 chr1:53392774 SCP2 -0.47 -7.78 -0.57 2.39e-12 Monocyte count; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.5 5.41 0.44 3.18e-7 Lymphocyte counts; TGCT cis rs7824557 0.734 rs2293856 chr8:11177447 C/T cg21775007 chr8:11205619 TDH 0.55 5.23 0.43 7.01e-7 Retinal vascular caliber; TGCT cis rs4689388 0.889 rs10026334 chr4:6294607 G/A cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12210905 1.000 rs72843643 chr6:27211247 G/C cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs116095464 0.510 rs55750776 chr5:230467 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg11494091 chr17:61959527 GH2 0.55 11.12 0.71 2.32e-20 Prudent dietary pattern; TGCT cis rs593982 1.000 rs118030231 chr11:65501905 G/A cg08755490 chr11:65554678 OVOL1 -1.48 -10.77 -0.7 1.68e-19 Atopic dermatitis; TGCT cis rs908922 1.000 rs908922 chr1:152454591 C/T cg20991723 chr1:152506922 NA 0.39 4.91 0.4 2.77e-6 Hair morphology; TGCT cis rs911555 0.723 rs2023395 chr14:103981971 A/G cg12935359 chr14:103987150 CKB 0.36 4.87 0.4 3.34e-6 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.932 rs13109475 chr4:17677565 C/G cg10189774 chr4:17578691 LAP3 -0.55 -4.75 -0.39 5.62e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2797160 1.000 rs1777195 chr6:126006861 A/C cg05901451 chr6:126070800 HEY2 0.74 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs35771425 0.619 rs6689078 chr1:211476423 C/G cg25617285 chr1:211431773 RCOR3 -0.51 -6.06 -0.48 1.5e-8 Educational attainment (years of education); TGCT cis rs9910055 0.502 rs1684662 chr17:42180822 T/A cg13607699 chr17:42295918 UBTF -0.59 -4.85 -0.4 3.63e-6 Total body bone mineral density; TGCT cis rs67460515 0.892 rs11710489 chr3:161093332 G/A cg03342759 chr3:160939853 NMD3 -0.49 -4.92 -0.4 2.74e-6 Parkinson's disease; TGCT cis rs6088580 0.608 rs1205342 chr20:32921842 C/T cg08999081 chr20:33150536 PIGU -0.25 -4.85 -0.4 3.66e-6 Glomerular filtration rate (creatinine); TGCT cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.61 -0.51 1.02e-9 Alzheimer's disease; TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg14851468 chr5:179071604 C5orf60 0.26 5.43 0.44 2.86e-7 Lung cancer; TGCT trans rs877282 0.898 rs11253353 chr10:766862 C/A cg22713356 chr15:30763199 NA 1.22 9.83 0.66 3.3e-17 Uric acid levels; TGCT cis rs651907 0.514 rs10936744 chr3:101433440 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.73 0.39 5.91e-6 Colorectal cancer; TGCT cis rs9914544 0.933 rs11871889 chr17:18771425 T/C cg26378065 chr17:18585709 ZNF286B 0.52 4.73 0.39 5.94e-6 Educational attainment (years of education); TGCT cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg18654377 chr3:49208889 KLHDC8B -0.33 -4.75 -0.39 5.62e-6 Parkinson's disease; TGCT cis rs2404602 0.655 rs4886507 chr15:77209694 T/C cg22467129 chr15:76604101 ETFA -0.5 -5.63 -0.45 1.12e-7 Blood metabolite levels; TGCT cis rs933688 1.000 rs2839728 chr5:90727412 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.89 8.36 0.6 1.08e-13 Smoking behavior; TGCT cis rs644799 0.635 rs10831428 chr11:95508404 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.29 0.6 1.54e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6088580 0.634 rs6059880 chr20:33088669 G/A cg08999081 chr20:33150536 PIGU 0.28 5.57 0.45 1.53e-7 Glomerular filtration rate (creatinine); TGCT cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs514406 0.505 rs6688064 chr1:53165609 C/T cg08859206 chr1:53392774 SCP2 -0.34 -4.74 -0.39 5.65e-6 Monocyte count; TGCT cis rs459571 0.959 rs2810491 chr9:136923331 C/T cg14405625 chr9:136855902 VAV2 0.3 4.57 0.38 1.16e-5 Platelet distribution width; TGCT cis rs7255045 0.752 rs11085822 chr19:12985576 A/G cg23899408 chr19:12877188 HOOK2 -0.61 -5.01 -0.41 1.79e-6 Mean corpuscular volume; TGCT cis rs2933343 0.553 rs71331686 chr3:128711428 T/A cg11901034 chr3:128598214 ACAD9 -0.57 -5.31 -0.43 4.92e-7 IgG glycosylation; TGCT cis rs2594989 1.000 rs2606756 chr3:11358181 G/A cg00170343 chr3:11313890 ATG7 0.66 4.87 0.4 3.39e-6 Circulating chemerin levels; TGCT cis rs10892173 0.765 rs7125694 chr11:117670657 C/T cg07621104 chr11:117668040 DSCAML1 0.49 5.16 0.42 9.7e-7 Myopia; TGCT cis rs10089 1.000 rs3805606 chr5:127470813 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.77 -7.48 -0.56 1.19e-11 Ileal carcinoids; TGCT cis rs3820928 1.000 rs12615988 chr2:227769000 A/G cg11843606 chr2:227700838 RHBDD1 -0.51 -4.5 -0.37 1.52e-5 Pulmonary function; TGCT cis rs13256369 0.901 rs12681327 chr8:8566414 G/T cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs7655441 0.964 rs4690132 chr4:80908043 G/C cg02241357 chr4:80885279 ANTXR2 -0.24 -4.59 -0.38 1.07e-5 Neutrophil percentage of white cells; TGCT cis rs3781663 0.963 rs3781662 chr11:69999501 A/G cg06393558 chr11:69982916 ANO1 -0.28 -4.45 -0.37 1.86e-5 Survival in rectal cancer; TGCT cis rs8051431 0.876 rs7192750 chr16:72014782 T/C cg06353428 chr16:71660113 MARVELD3 0.58 4.9 0.4 2.98e-6 LDL cholesterol levels; TGCT cis rs10206020 0.885 rs13388254 chr2:1577209 A/G cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs1153858 1.000 rs1145091 chr15:45649996 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs7677751 0.806 rs7679903 chr4:55097373 T/C cg17187183 chr4:55093834 PDGFRA 0.55 7.06 0.54 1.05e-10 Corneal astigmatism; TGCT cis rs2439831 0.681 rs478104 chr15:43594900 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.0 8.18 0.59 2.93e-13 Lung cancer in ever smokers; TGCT cis rs2663905 0.706 rs2683260 chr15:81385552 A/C cg18837035 chr15:81426597 C15orf26 -0.79 -6.72 -0.52 6e-10 QT interval (drug interaction); TGCT cis rs2456568 0.802 rs1506656 chr11:93639813 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.35 -0.5 3.75e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7772486 0.754 rs12199362 chr6:146118225 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.99 0.41 2.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.902 rs2777480 chr6:146309983 T/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 9.88e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs68170813 0.599 rs6466162 chr7:106902625 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs1008375 0.931 rs10939734 chr4:17570709 C/T cg16339924 chr4:17578868 LAP3 0.82 7.13 0.54 7.32e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4808199 0.948 rs7259434 chr19:19428805 A/T cg02546618 chr19:19431379 KIAA0892;SF4 0.64 4.75 0.39 5.58e-6 Nonalcoholic fatty liver disease; TGCT cis rs3127573 0.843 rs3798156 chr6:160676216 C/T cg20707008 chr6:160210612 MRPL18;TCP1 0.84 4.58 0.38 1.1e-5 Creatinine levels; TGCT cis rs1105881 0.541 rs2277536 chr15:41857303 T/C cg17847044 chr15:42102381 MAPKBP1 -0.22 -5.46 -0.44 2.5e-7 Educational attainment; TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs2840044 0.534 rs2124246 chr17:33885431 G/A cg05299278 chr17:33885742 SLFN14 0.22 4.92 0.4 2.7e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs875971 0.830 rs7799834 chr7:65880694 A/C cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs3008870 0.920 rs12132532 chr1:67457015 G/T cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs13188771 0.651 rs10515312 chr5:100906519 G/T cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg13409248 chr3:40428643 ENTPD3 0.57 4.62 0.38 9.51e-6 Renal cell carcinoma; TGCT cis rs4891159 0.790 rs660029 chr18:74149668 A/G cg24786174 chr18:74118243 ZNF516 0.57 8.54 0.61 4.12e-14 Longevity; TGCT cis rs9611565 0.592 rs12484254 chr22:41962003 T/A cg03806693 chr22:41940476 POLR3H -1.08 -11.36 -0.71 6.34e-21 Vitiligo; TGCT cis rs7528419 0.927 rs660240 chr1:109817838 T/C cg00908766 chr1:109817496 CELSR2 0.53 5.37 0.43 3.78e-7 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs7246657 0.943 rs4803347 chr19:37848017 G/A cg18154014 chr19:37997991 ZNF793 0.71 5.11 0.42 1.2e-6 Coronary artery calcification; TGCT cis rs7666738 0.830 rs34164616 chr4:99015251 G/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2708977 1.000 rs1011040 chr2:97212755 A/G cg01950434 chr2:97203154 ARID5A -0.59 -5.62 -0.45 1.19e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs28595532 0.920 rs56322132 chr4:119742496 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7681440 0.874 rs7687945 chr4:90764699 C/T cg26578617 chr4:90757533 SNCA -0.49 -5.1 -0.42 1.26e-6 Dementia with Lewy bodies; TGCT cis rs2299587 0.698 rs2283113 chr8:17880243 C/A cg01800426 chr8:17659068 MTUS1 -0.56 -4.77 -0.39 5.17e-6 Economic and political preferences; TGCT trans rs1005277 0.579 rs2800485 chr10:38542588 G/A cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg08219700 chr8:58056026 NA 0.35 4.56 0.38 1.2e-5 Developmental language disorder (linguistic errors); TGCT cis rs7973719 0.833 rs3825405 chr12:7360143 G/T cg07052231 chr12:7363540 PEX5 0.37 5.76 0.46 6.19e-8 IgG glycosylation; TGCT cis rs11690935 1.000 rs3795999 chr2:172544483 A/G cg13550731 chr2:172543902 DYNC1I2 1.21 13.07 0.76 4.43e-25 Schizophrenia; TGCT cis rs6840360 0.571 rs28608620 chr4:152504791 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.533 rs4696297 chr4:152725838 T/G cg22705602 chr4:152727874 NA 0.33 6.0 0.47 2.01e-8 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.904 rs2338797 chr17:37548241 G/A cg07936489 chr17:37558343 FBXL20 0.64 4.94 0.41 2.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg10295955 chr4:187884368 NA -0.99 -15.24 -0.81 3.38e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs79349575 0.681 rs56080003 chr17:47019049 A/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs41271951 0.512 rs11204765 chr1:151016757 G/A cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs546131 1.000 rs546131 chr11:34851760 G/C cg11058730 chr11:34937778 PDHX;APIP 0.57 5.04 0.41 1.63e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7829975 0.511 rs2948286 chr8:8130160 A/G cg06636001 chr8:8085503 FLJ10661 0.73 6.42 0.5 2.67e-9 Mood instability; TGCT cis rs1395 0.744 rs1975384 chr2:27542041 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 8.02 0.58 6.76e-13 Blood metabolite levels; TGCT cis rs1670533 1.000 rs11247972 chr4:1060550 A/G cg20887711 chr4:1340912 KIAA1530 0.65 5.07 0.41 1.38e-6 Recombination rate (females); TGCT cis rs6752107 0.901 rs11679791 chr2:234156536 G/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.86 0.4 3.44e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs8177253 1.000 rs1358023 chr3:133484393 T/C cg16414030 chr3:133502952 NA -0.61 -9.62 -0.65 1.03e-16 Iron status biomarkers; TGCT cis rs696279 0.869 rs697509 chr7:16700495 G/A cg08595592 chr7:16780162 NA 0.25 4.78 0.39 4.77e-6 Mean platelet volume; TGCT cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg00786635 chr1:25594202 NA 0.6 6.24 0.49 6.44e-9 Plateletcrit;Mean corpuscular volume; TGCT cis rs7772486 0.754 rs4566902 chr6:146244128 A/G cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs6089829 0.926 rs1060491 chr20:61665817 C/A cg02380750 chr20:61661411 NA -0.3 -5.21 -0.42 7.68e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs1059312 0.966 rs12370194 chr12:129277250 A/T cg09035930 chr12:129282057 SLC15A4 0.6 11.86 0.73 3.65e-22 Systemic lupus erythematosus; TGCT cis rs6427419 0.725 rs7514301 chr1:158057420 A/T cg07184316 chr1:157669111 FCRL3 -0.24 -4.51 -0.38 1.5e-5 Obesity-related traits; TGCT cis rs854765 0.575 rs7207821 chr17:17891781 A/G cg04398451 chr17:18023971 MYO15A -0.33 -5.3 -0.43 5.16e-7 Total body bone mineral density; TGCT cis rs514406 0.505 rs448788 chr1:53161620 A/G cg25767906 chr1:53392781 SCP2 0.45 4.84 0.4 3.78e-6 Monocyte count; TGCT cis rs4319547 0.695 rs11058034 chr12:122894936 G/T cg16389456 chr12:123636548 NA -0.29 -4.93 -0.41 2.53e-6 Body mass index; TGCT cis rs4953076 0.533 rs10173126 chr2:44446492 T/C cg00619915 chr2:44497795 NA -0.23 -5.15 -0.42 9.99e-7 Height; TGCT trans rs629535 0.911 rs688612 chr8:70011887 C/T cg21567404 chr3:27674614 NA -0.58 -9.2 -0.64 1.1e-15 Dupuytren's disease; TGCT cis rs1801251 1.000 rs6437074 chr2:233712296 C/T cg08000102 chr2:233561755 GIGYF2 -0.63 -6.42 -0.5 2.64e-9 Coronary artery disease; TGCT cis rs7666738 0.830 rs7662114 chr4:99019985 A/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6684514 0.922 rs12037778 chr1:156284864 A/G cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs11249608 0.548 rs17078991 chr5:178459426 A/C cg23951258 chr5:178450506 ZNF879 0.44 4.56 0.38 1.23e-5 Pubertal anthropometrics; TGCT trans rs842828 0.710 rs296780 chr2:201239485 C/T cg01425746 chr11:45671369 CHST1 0.66 6.65 0.51 8.36e-10 Urate levels in lean individuals; TGCT cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg03517284 chr6:25882590 NA -0.77 -8.05 -0.59 5.9e-13 Blood metabolite levels; TGCT cis rs9325144 0.647 rs870431 chr12:38953073 T/C cg10518543 chr12:38710700 ALG10B -0.49 -4.68 -0.39 7.26e-6 Morning vs. evening chronotype; TGCT cis rs7772486 0.597 rs2485631 chr6:146190077 G/C cg13319975 chr6:146136371 FBXO30 -0.67 -6.02 -0.48 1.84e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs9399137 0.507 rs4896128 chr6:135349756 A/G cg24558204 chr6:135376177 HBS1L -0.45 -4.74 -0.39 5.74e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs112591243 0.570 rs17393980 chr21:47971060 C/T cg10657630 chr21:48055338 PRMT2 1.03 4.98 0.41 2.1e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs7635838 0.819 rs4684072 chr3:11514860 A/G cg00170343 chr3:11313890 ATG7 0.69 6.67 0.51 7.44e-10 HDL cholesterol; TGCT cis rs11673344 0.543 rs8108429 chr19:37636776 A/C cg08039142 chr19:36980659 ZNF566 0.52 4.69 0.39 7.06e-6 Obesity-related traits; TGCT cis rs7681440 0.874 rs1372525 chr4:90776165 G/A cg20003494 chr4:90757398 SNCA -0.56 -5.35 -0.43 4.11e-7 Dementia with Lewy bodies; TGCT cis rs6570726 0.791 rs6913727 chr6:145899826 A/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs78487399 0.808 rs10168889 chr2:43841717 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.69 5.06 0.41 1.47e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs330048 0.509 rs36111783 chr8:9145588 A/G cg15556689 chr8:8085844 FLJ10661 0.66 6.64 0.51 8.62e-10 Systemic lupus erythematosus; TGCT cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg18765753 chr7:1198926 ZFAND2A -0.51 -5.96 -0.47 2.38e-8 Longevity;Endometriosis; TGCT cis rs35883536 0.647 rs34195036 chr1:101040429 C/A cg06223162 chr1:101003688 GPR88 -0.42 -8.0 -0.58 7.5e-13 Monocyte count; TGCT cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs17376456 0.877 rs28637444 chr5:93495548 C/T cg21475434 chr5:93447410 FAM172A 0.63 4.63 0.38 8.98e-6 Diabetic retinopathy; TGCT cis rs6992820 0.902 rs13274826 chr8:56764794 G/T cg06880721 chr8:56792545 LYN -0.68 -5.76 -0.46 6.32e-8 Mean platelet volume; TGCT cis rs9948 0.655 rs62156221 chr2:97410850 A/G cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs3617 0.625 rs3774364 chr3:52863605 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.52 -0.38 1.4e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7246657 0.550 rs9941475 chr19:38064517 C/T cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs6700896 0.500 rs4655740 chr1:66084309 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7617773 0.539 rs13069884 chr3:48381148 T/A cg11946769 chr3:48343235 NME6 0.55 4.6 0.38 1.02e-5 Coronary artery disease; TGCT trans rs10435719 0.610 rs76311455 chr8:11790526 C/G cg15556689 chr8:8085844 FLJ10661 0.75 6.87 0.53 2.77e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs3087591 0.960 rs9303642 chr17:29578360 A/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.56 -0.56 7.74e-12 Hip circumference; TGCT cis rs933688 1.000 rs1363839 chr5:90671274 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.12 0.67 6.38e-18 Smoking behavior; TGCT cis rs854765 0.583 rs8078583 chr17:17811465 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.95 0.58 1.01e-12 Total body bone mineral density; TGCT cis rs9611565 0.512 rs132767 chr22:42009520 C/T cg06634786 chr22:41940651 POLR3H -0.81 -7.48 -0.56 1.21e-11 Vitiligo; TGCT cis rs1525293 0.646 rs10269409 chr7:70490054 C/T cg21135135 chr7:70597687 WBSCR17 -0.52 -5.14 -0.42 1.04e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs6484504 0.532 rs7117286 chr11:31283810 T/A cg26647111 chr11:31128758 NA -0.35 -4.84 -0.4 3.83e-6 Red blood cell count; TGCT cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.81 0.4 4.26e-6 Bipolar disorder; TGCT cis rs7677751 0.806 rs1800812 chr4:55094629 G/T cg17187183 chr4:55093834 PDGFRA 0.55 7.06 0.54 1.05e-10 Corneal astigmatism; TGCT cis rs9583531 0.689 rs9515273 chr13:111383427 G/C cg24331049 chr13:111365604 ING1 0.87 8.58 0.61 3.25e-14 Coronary artery disease; TGCT cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg21724239 chr8:58056113 NA 0.4 4.62 0.38 9.57e-6 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.647 rs36114653 chr15:77025393 G/A cg22467129 chr15:76604101 ETFA 0.48 4.77 0.39 5.15e-6 Blood metabolite levels; TGCT cis rs28595532 0.920 rs56283736 chr4:119747268 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs769267 0.896 rs7253807 chr19:19631444 A/T cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs6988636 1.000 rs57902736 chr8:124189893 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs12369635 1.000 rs12369635 chr12:129561356 C/T cg01909103 chr12:129572610 TMEM132D -0.64 -4.47 -0.37 1.73e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs10927875 0.632 rs7535248 chr1:16129598 C/T cg21385522 chr1:16154831 NA -0.96 -15.71 -0.82 2.84e-31 Dilated cardiomyopathy; TGCT cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg06238570 chr21:40685208 BRWD1 0.82 9.01 0.63 3.07e-15 Cognitive function; TGCT cis rs17102423 0.654 rs8015921 chr14:65523015 G/A cg11161011 chr14:65562177 MAX -0.46 -6.17 -0.48 8.9e-9 Obesity-related traits; TGCT cis rs778371 0.834 rs778364 chr2:233777859 A/G cg08000102 chr2:233561755 GIGYF2 0.49 4.52 0.38 1.44e-5 Schizophrenia; TGCT cis rs4366490 0.534 rs7120661 chr11:62864385 A/G cg21002970 chr11:62369079 MTA2 0.67 4.7 0.39 6.87e-6 Conotruncal heart defects; TGCT cis rs11577318 0.853 rs17645 chr1:26646730 A/G cg04990556 chr1:26633338 UBXN11 -0.59 -4.94 -0.41 2.47e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs3935685 0.874 rs34906247 chr15:78004204 A/G cg03457338 chr15:78040120 NA -0.21 -5.54 -0.45 1.72e-7 Intelligence (multi-trait analysis); TGCT cis rs9443645 0.901 rs9343856 chr6:79678211 G/A cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.56e-6 Intelligence (multi-trait analysis); TGCT cis rs4849845 0.573 rs33971369 chr2:121024987 A/G cg24070213 chr2:121070622 NA 0.35 4.8 0.4 4.43e-6 Mean platelet volume; TGCT cis rs4665809 0.838 rs7565843 chr2:26292912 G/C cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs9811920 0.660 rs7619512 chr3:99729132 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.34 0.43 4.29e-7 Axial length; TGCT cis rs7772486 0.743 rs9376955 chr6:145949404 T/A cg23711669 chr6:146136114 FBXO30 0.79 8.38 0.6 9.86e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs6547741 0.935 rs12714204 chr2:27787540 T/C cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs13190036 1.000 rs13157667 chr5:176613877 C/T cg18465082 chr5:176734745 MXD3 0.32 4.44 0.37 1.95e-5 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs2242194 0.844 rs11264295 chr1:154987526 C/T cg12436631 chr1:155007014 DCST1;DCST2 0.26 6.93 0.53 2.02e-10 Schizophrenia; TGCT cis rs6121246 0.954 rs6121245 chr20:30432060 G/A cg18721089 chr20:30220636 NA -0.45 -4.98 -0.41 2.12e-6 Mean corpuscular hemoglobin; TGCT cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs11249608 0.600 rs13359570 chr5:178449249 T/G cg01312482 chr5:178451176 ZNF879 -0.58 -5.77 -0.46 5.94e-8 Pubertal anthropometrics; TGCT cis rs7772486 0.754 rs9399567 chr6:146147295 C/T cg23711669 chr6:146136114 FBXO30 0.91 10.49 0.69 8.21e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs2549003 0.966 rs839 chr5:131819126 C/T cg02551604 chr5:131831745 NA -0.89 -11.95 -0.73 2.33e-22 Asthma (sex interaction); TGCT cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg22166914 chr1:53195759 ZYG11B -0.46 -8.42 -0.6 7.72e-14 Monocyte count; TGCT cis rs6912958 0.703 rs9362427 chr6:88097634 G/T cg12350822 chr6:88032061 C6orf162;GJB7 0.4 5.18 0.42 8.73e-7 Monocyte percentage of white cells; TGCT cis rs614226 0.935 rs7137953 chr12:120894685 C/T cg10072921 chr12:121022843 NA 0.45 4.69 0.39 7.09e-6 Type 1 diabetes nephropathy; TGCT cis rs4851266 1.000 rs893246 chr2:100814917 T/C cg07810366 chr2:100720526 AFF3 -0.4 -5.75 -0.46 6.53e-8 Educational attainment; TGCT cis rs78487399 0.710 rs17031000 chr2:43758625 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -4.72 -0.39 6.22e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10193935 0.901 rs12619348 chr2:42625586 C/T cg27598129 chr2:42591480 NA -0.35 -5.04 -0.41 1.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7226408 0.948 rs72885224 chr18:34401378 C/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg21237687 chr17:6899380 ALOX12 -0.47 -5.19 -0.42 8.42e-7 Tonsillectomy; TGCT cis rs10744422 0.764 rs10773599 chr12:123297419 A/T cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs4273100 0.646 rs4924987 chr17:19247075 G/A cg01534423 chr17:18965556 NA -0.79 -7.19 -0.54 5.25e-11 Schizophrenia; TGCT cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs941408 1.000 rs1640271 chr19:2799979 C/T cg06609049 chr19:2785107 THOP1 0.82 7.73 0.57 3.18e-12 Total cholesterol levels; TGCT cis rs7666738 0.830 rs34273190 chr4:99004568 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1475911 1.000 rs17114359 chr21:43510437 A/C cg19766460 chr21:43528205 UMODL1;C21orf128 0.54 7.44 0.56 1.48e-11 IgG glycosylation; TGCT cis rs1008375 1.000 rs10939746 chr4:17684951 A/G cg10189774 chr4:17578691 LAP3 -0.57 -5.1 -0.42 1.23e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9916302 0.904 rs2303316 chr17:37704217 A/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.92 -0.4 2.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg08048268 chr3:133502702 NA -0.54 -7.2 -0.54 5.06e-11 Iron status biomarkers; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg00024416 chr22:24240387 NA -0.24 -4.61 -0.38 9.69e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs911555 0.755 rs1138400 chr14:103956833 A/G cg12935359 chr14:103987150 CKB -0.33 -4.59 -0.38 1.07e-5 Intelligence (multi-trait analysis); TGCT cis rs58235267 0.656 rs12713469 chr2:63059927 C/T cg17519650 chr2:63277830 OTX1 -0.54 -4.97 -0.41 2.2e-6 Prostate-specific antigen levels (conditioned on lead SNPs); TGCT cis rs72781680 0.699 rs72796125 chr2:23919169 C/T cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT trans rs12599106 0.839 rs3853177 chr16:34498532 A/G cg26668828 chr6:292823 DUSP22 -0.77 -8.12 -0.59 4.02e-13 Menopause (age at onset); TGCT cis rs4819052 0.808 rs11909411 chr21:46676556 A/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs2624839 0.602 rs2526390 chr3:50192760 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.77 6.99 0.53 1.5e-10 Intelligence (multi-trait analysis); TGCT cis rs7542091 0.748 rs2357231 chr1:210028454 A/C cg06375148 chr1:209958343 C1orf74 -0.25 -4.55 -0.38 1.26e-5 Monobrow; TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs9527 0.590 rs726010 chr10:104841977 C/T cg04362960 chr10:104952993 NT5C2 0.67 5.63 0.45 1.16e-7 Arsenic metabolism; TGCT cis rs9527 0.590 rs763914 chr10:104841587 T/C cg04362960 chr10:104952993 NT5C2 0.66 5.61 0.45 1.25e-7 Arsenic metabolism; TGCT cis rs1008375 0.932 rs11938710 chr4:17670664 G/C cg16339924 chr4:17578868 LAP3 -0.59 -4.83 -0.4 3.97e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6060987 1 rs6060987 chr20:30427077 T/A cg18721089 chr20:30220636 NA -0.45 -4.98 -0.41 2.12e-6 Mean corpuscular volume; TGCT cis rs478304 0.934 rs1193496 chr11:65537556 C/T cg27068330 chr11:65405492 SIPA1 -0.76 -7.35 -0.55 2.37e-11 Acne (severe); TGCT cis rs9443645 0.901 rs1572584 chr6:79690290 A/G cg09184832 chr6:79620586 NA 0.46 4.98 0.41 2.08e-6 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.555 rs10785454 chr12:38476260 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6570726 0.791 rs4332001 chr6:145934841 T/C cg23711669 chr6:146136114 FBXO30 0.83 8.67 0.61 2.02e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs1799949 0.965 rs9911630 chr17:41188342 A/G cg23758822 chr17:41437982 NA 0.6 6.0 0.47 1.99e-8 Menopause (age at onset); TGCT cis rs72781680 1.000 rs56104215 chr2:24133590 T/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs11250097 0.549 rs11778177 chr8:11310362 C/T cg21775007 chr8:11205619 TDH -0.53 -4.87 -0.4 3.31e-6 Neuroticism; TGCT cis rs904251 1.000 rs904251 chr6:37451696 G/T cg08126542 chr6:37504118 NA -0.4 -5.27 -0.43 5.92e-7 Cognitive performance; TGCT cis rs9611565 0.568 rs5758441 chr22:42132888 C/A cg03806693 chr22:41940476 POLR3H 0.93 9.08 0.63 2.06e-15 Vitiligo; TGCT cis rs79349575 0.783 rs62075852 chr17:47017176 T/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg08859206 chr1:53392774 SCP2 -0.43 -6.71 -0.52 6.09e-10 Monocyte count; TGCT cis rs80282103 0.618 rs74117848 chr10:1160974 T/G cg08668510 chr10:1095578 IDI1 1.06 5.03 0.41 1.7e-6 Glomerular filtration rate (creatinine); TGCT cis rs11190604 1.000 rs2495736 chr10:102338410 T/C cg16342193 chr10:102329863 NA -0.43 -5.39 -0.44 3.43e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs36051895 0.632 rs10815165 chr9:5149138 T/C cg02405213 chr9:5042618 JAK2 -0.72 -9.36 -0.64 4.43e-16 Pediatric autoimmune diseases; TGCT cis rs981844 1.000 rs62325085 chr4:154663283 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs35306767 0.761 rs12359796 chr10:1021479 G/C cg26597838 chr10:835615 NA 0.58 6.42 0.5 2.64e-9 Eosinophil percentage of granulocytes; TGCT cis rs28595532 0.920 rs116091383 chr4:119635518 A/G cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs881375 0.678 rs10985102 chr9:123707497 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.73 0.39 6.09e-6 Rheumatoid arthritis; TGCT cis rs8037137 0.915 rs60290423 chr15:91529452 T/C cg22570213 chr15:91497863 RCCD1 0.49 4.69 0.39 6.96e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs4499344 0.730 rs614361 chr19:33106387 C/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.74 0.62 1.36e-14 Mean platelet volume; TGCT cis rs8017423 0.967 rs11845329 chr14:90727749 C/T cg04374321 chr14:90722782 PSMC1 0.78 7.86 0.58 1.59e-12 Mortality in heart failure; TGCT cis rs6429082 0.714 rs704719 chr1:235667170 G/A cg26050004 chr1:235667680 B3GALNT2 0.6 5.4 0.44 3.32e-7 Adiposity; TGCT cis rs1577917 1.000 rs955227 chr6:86651032 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.36 -0.43 3.86e-7 Response to antipsychotic treatment; TGCT cis rs6951245 0.882 rs10256720 chr7:1210825 C/G cg18402987 chr7:1209562 NA 0.88 7.18 0.54 5.54e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8180040 0.654 rs1466740 chr3:47245883 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.35 -0.6 1.13e-13 Colorectal cancer; TGCT cis rs7666738 0.830 rs13112037 chr4:98976986 A/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs6089829 0.889 rs6090206 chr20:61668363 G/A cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs40363 0.723 rs757269 chr16:3538003 A/G cg22508957 chr16:3507546 NAT15 -0.51 -4.69 -0.39 7.08e-6 Tuberculosis; TGCT cis rs1008375 0.897 rs6820164 chr4:17630115 G/A cg16339924 chr4:17578868 LAP3 0.71 5.7 0.46 8.2e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11098499 0.954 rs10014845 chr4:120301077 T/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs9341808 0.690 rs3805926 chr6:80879280 C/G cg08355045 chr6:80787529 NA 0.32 5.64 0.45 1.11e-7 Sitting height ratio; TGCT cis rs826838 0.616 rs9668847 chr12:38614669 C/T cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Heart rate; TGCT cis rs7666738 0.546 rs13105521 chr4:98734419 C/T cg17366294 chr4:99064904 C4orf37 0.59 5.57 0.45 1.48e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4699052 0.662 rs1516732 chr4:104251154 A/T cg16532752 chr4:104119610 CENPE -0.5 -4.88 -0.4 3.2e-6 Testicular germ cell tumor; TGCT cis rs7208859 0.673 rs9894876 chr17:29182020 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs1499614 1.000 rs60326618 chr7:66166358 G/A cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs4285028 0.948 rs13067270 chr3:121673901 A/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs9653442 0.545 rs10496344 chr2:100764125 C/T cg07810366 chr2:100720526 AFF3 0.37 5.46 0.44 2.45e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2013441 1.000 rs2189710 chr17:20078964 C/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs9788682 0.747 rs12910984 chr15:78891627 G/A cg24631222 chr15:78858424 CHRNA5 -0.83 -6.21 -0.49 7.37e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9291683 0.525 rs12506455 chr4:10031569 T/A cg11266682 chr4:10021025 SLC2A9 0.64 8.92 0.63 5e-15 Bone mineral density; TGCT cis rs10791097 0.694 rs2155749 chr11:130751094 G/T cg12179176 chr11:130786555 SNX19 0.82 10.15 0.67 5.45e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs924607 0.900 rs1697950 chr5:616890 G/A cg18765565 chr5:669397 TPPP -0.62 -6.72 -0.52 6e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7249142 0.562 rs1050544 chr19:19287901 A/G cg08207377 chr19:19281140 LOC729991-MEF2B;MEF2B -0.48 -4.63 -0.38 9.08e-6 IgG glycosylation; TGCT cis rs2299587 0.637 rs6586677 chr8:17890687 A/G cg01800426 chr8:17659068 MTUS1 -0.61 -5.17 -0.42 9.09e-7 Economic and political preferences; TGCT cis rs8077889 0.703 rs231531 chr17:41946180 A/C cg26893861 chr17:41843967 DUSP3 1.04 9.69 0.66 6.95e-17 Triglycerides; TGCT cis rs9814567 0.896 rs6763188 chr3:134349995 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.84 7.7 0.57 3.76e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3087591 0.708 rs2525569 chr17:29675971 T/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.52 0.44 1.87e-7 Hip circumference; TGCT cis rs12210905 0.614 rs12199685 chr6:27323486 G/A cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.45 0.44 2.66e-7 Height; TGCT cis rs6495122 0.699 rs1378941 chr15:75080150 C/A cg10253484 chr15:75165896 SCAMP2 -0.68 -6.01 -0.48 1.87e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs6089829 0.962 rs9680064 chr20:61666168 G/A cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs28595532 0.920 rs17324968 chr4:119772316 A/G cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg18305652 chr10:134549665 INPP5A 0.31 5.07 0.41 1.42e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9948 1.000 rs62152790 chr2:97478579 G/A cg01990225 chr2:97406019 LMAN2L -0.83 -4.67 -0.39 7.67e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs6912958 0.514 rs1980792 chr6:87889917 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.42 -5.44 -0.44 2.74e-7 Monocyte percentage of white cells; TGCT cis rs769267 0.930 rs1865034 chr19:19605763 C/T cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs6840360 0.533 rs13147021 chr4:152722688 A/C cg17479576 chr4:152424074 FAM160A1 0.46 4.83 0.4 3.88e-6 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg00024416 chr22:24240387 NA -0.26 -4.96 -0.41 2.25e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg20637647 chr7:64974828 NA 0.88 5.12 0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs4689388 0.926 rs28420833 chr4:6279504 G/A cg14416269 chr4:6271139 WFS1 0.38 5.23 0.42 7.12e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7208859 0.623 rs58089675 chr17:29196764 C/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs5750830 0.621 rs743838 chr22:39824707 T/G cg05872129 chr22:39784769 NA -0.98 -10.82 -0.7 1.27e-19 Intelligence (multi-trait analysis); TGCT cis rs941873 0.803 rs2105461 chr10:81101679 A/G cg09469691 chr10:81107165 PPIF -0.57 -5.8 -0.46 5.1e-8 Height; TGCT cis rs12541335 0.639 rs35068739 chr8:22201719 T/C cg00420450 chr8:22132641 PIWIL2 0.23 4.56 0.38 1.19e-5 Hypertriglyceridemia; TGCT cis rs9303401 0.625 rs66508449 chr17:56691034 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs425277 0.565 rs2480711 chr1:2111376 A/G cg24578937 chr1:2090814 PRKCZ 0.27 7.01 0.53 1.38e-10 Height; TGCT cis rs2290402 0.536 rs56080039 chr4:886519 G/A cg11315544 chr4:1222440 CTBP1 0.26 4.46 0.37 1.84e-5 Type 2 diabetes; TGCT cis rs1552244 0.882 rs3755782 chr3:10029305 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs10501293 0.956 rs11037235 chr11:43100381 G/C cg03447554 chr11:43094025 NA -0.5 -6.92 -0.53 2.09e-10 Cognitive performance; TGCT cis rs4595586 0.545 rs4254106 chr12:39389342 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs3858526 0.916 rs11039551 chr11:5930773 C/T cg13902645 chr11:5959945 NA -0.44 -4.8 -0.4 4.54e-6 DNA methylation (variation); TGCT cis rs7824557 0.593 rs11774673 chr8:11191537 T/C cg21775007 chr8:11205619 TDH 0.7 6.86 0.52 2.93e-10 Retinal vascular caliber; TGCT cis rs6835098 1.000 rs1054497 chr4:174089048 A/T cg08422745 chr4:174089978 GALNT7 0.93 11.26 0.71 1.08e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7659604 0.582 rs3217780 chr4:122737278 T/C cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.24e-7 Type 2 diabetes; TGCT cis rs4253772 0.513 rs12171124 chr22:46710693 A/C cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs858239 0.601 rs6971002 chr7:23172304 C/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.24 -0.43 6.57e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs11148252 0.538 rs2897976 chr13:52715944 G/A cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.88e-8 Lewy body disease; TGCT cis rs3087591 0.960 rs2940184 chr17:29423119 T/C cg24425628 chr17:29625626 OMG;NF1 0.47 7.21 0.54 4.89e-11 Hip circumference; TGCT cis rs1670533 1.000 rs34956924 chr4:1047270 T/C cg20887711 chr4:1340912 KIAA1530 0.72 5.74 0.46 6.72e-8 Recombination rate (females); TGCT cis rs1062177 0.756 rs2964592 chr5:151115688 A/G cg00977110 chr5:151150581 G3BP1 -0.39 -4.51 -0.38 1.47e-5 Preschool internalizing problems; TGCT cis rs9818758 0.607 rs55873331 chr3:49597055 C/T cg00383909 chr3:49044727 WDR6 1.31 6.63 0.51 9.3e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7100689 0.516 rs10887711 chr10:82034842 A/G cg01528321 chr10:82214614 TSPAN14 0.63 6.15 0.48 9.93e-9 Post bronchodilator FEV1; TGCT cis rs1322512 1.000 rs1407488 chr6:152945777 G/T cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs9527 0.590 rs7087040 chr10:104799668 G/A cg04362960 chr10:104952993 NT5C2 0.65 5.59 0.45 1.36e-7 Arsenic metabolism; TGCT cis rs2777491 1.000 rs7177641 chr15:41743426 C/T cg18705301 chr15:41695430 NDUFAF1 -0.74 -8.89 -0.62 6.08e-15 Ulcerative colitis; TGCT cis rs12893668 0.703 rs34896432 chr14:104027995 C/T cg26031613 chr14:104095156 KLC1 -0.54 -4.55 -0.38 1.28e-5 Reticulocyte count; TGCT cis rs731174 0.797 rs510208 chr1:38147166 A/G cg22449745 chr1:38156939 CDCA8;C1orf109 -0.27 -4.56 -0.38 1.22e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs1801251 0.727 rs13029336 chr2:233569935 A/G cg25237894 chr2:233734115 C2orf82 -0.25 -4.71 -0.39 6.51e-6 Coronary artery disease; TGCT cis rs6701037 0.714 rs2285219 chr1:175130983 A/T cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT cis rs10206020 0.885 rs6720923 chr2:1574197 T/C cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg12310025 chr6:25882481 NA -0.54 -5.47 -0.44 2.39e-7 Blood metabolite levels; TGCT cis rs12540874 0.670 rs3887826 chr7:50544961 G/A cg18232548 chr7:50535776 DDC -0.38 -6.7 -0.52 6.66e-10 Systemic sclerosis; TGCT cis rs2274459 0.572 rs116454384 chr6:33646375 C/T cg00898486 chr6:34006557 GRM4 0.32 4.78 0.39 4.86e-6 Obesity (extreme); TGCT cis rs6138458 0.962 rs6036976 chr20:24901567 T/G cg26195577 chr20:24973756 C20orf3 -1.2 -12.04 -0.73 1.35e-22 Blood protein levels; TGCT cis rs1949733 0.917 rs10461079 chr4:8392724 G/A cg13073564 chr4:8508604 NA 0.5 5.43 0.44 2.88e-7 Response to antineoplastic agents; TGCT cis rs1348850 0.634 rs2293471 chr2:178487729 T/G cg19192590 chr2:178524533 PDE11A 0.5 4.58 0.38 1.1e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9326248 0.581 rs7120515 chr11:116991926 A/G cg20608306 chr11:116969690 SIK3 0.39 4.58 0.38 1.12e-5 Blood protein levels; TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg18765753 chr7:1198926 ZFAND2A -0.53 -6.53 -0.51 1.49e-9 Longevity;Endometriosis; TGCT cis rs1801251 1.000 rs2305137 chr2:233712049 G/A cg25237894 chr2:233734115 C2orf82 -0.31 -5.42 -0.44 2.98e-7 Coronary artery disease; TGCT cis rs5769765 0.542 rs5770720 chr22:50253101 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.97 6.35 0.5 3.69e-9 Schizophrenia; TGCT cis rs4266144 0.558 rs4680339 chr3:156835419 G/T cg25506747 chr3:157813810 SHOX2 -0.35 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs1018836 0.892 rs1476428 chr8:91555603 G/T cg16814680 chr8:91681699 NA -0.74 -7.48 -0.56 1.15e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg20007245 chr22:24372913 LOC391322 -0.72 -7.11 -0.54 8.1e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10746514 0.833 rs12039526 chr1:232272599 C/T cg09506761 chr1:232265262 NA -0.5 -5.09 -0.42 1.28e-6 Response to statin therapy; TGCT cis rs9674544 0.757 rs9896443 chr17:47125982 A/G cg07075026 chr17:47091521 IGF2BP1 -0.45 -5.28 -0.43 5.68e-7 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs9611565 0.592 rs57102627 chr22:41987627 T/C cg06481639 chr22:41940642 POLR3H -0.62 -5.26 -0.43 6.21e-7 Vitiligo; TGCT cis rs2677744 0.719 rs2002739 chr15:91452106 C/T cg23684204 chr15:91497937 RCCD1 0.36 5.14 0.42 1.02e-6 Attention deficit hyperactivity disorder; TGCT cis rs68170813 0.559 rs2107318 chr7:106845969 A/G cg02696742 chr7:106810147 HBP1 -0.67 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs13082711 0.953 rs35124294 chr3:27539526 A/G cg02860705 chr3:27208620 NA 0.34 4.64 0.38 8.68e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2862064 0.872 rs4704734 chr5:156480406 G/A cg12943317 chr5:156479607 HAVCR1 -0.41 -5.23 -0.43 6.98e-7 Platelet count; TGCT cis rs73198271 0.628 rs11776981 chr8:8589459 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs6964587 1.000 rs6970277 chr7:91680655 T/C cg17063962 chr7:91808500 NA 0.88 9.54 0.65 1.69e-16 Breast cancer; TGCT cis rs6540559 0.673 rs6540561 chr1:209982255 C/T cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg23262073 chr20:60523788 NA -0.36 -5.74 -0.46 6.78e-8 Obesity-related traits; TGCT cis rs7223966 1.000 rs7223412 chr17:61808172 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg16325326 chr1:53192061 ZYG11B -0.58 -6.41 -0.5 2.75e-9 Monocyte count; TGCT cis rs6991838 0.593 rs7011464 chr8:66635287 A/T cg14353373 chr8:66472662 NA -0.46 -4.63 -0.38 9.25e-6 Intelligence (multi-trait analysis); TGCT cis rs877282 0.945 rs71491303 chr10:772884 G/T cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs3806843 0.547 rs246048 chr5:140327900 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs2742417 1.000 rs2673037 chr3:45749094 A/T cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9810089 0.835 rs654237 chr3:136068699 T/C cg12473912 chr3:136751656 NA 0.35 5.04 0.41 1.59e-6 Gestational age at birth (child effect); TGCT cis rs11249608 0.548 rs2047354 chr5:178455247 T/C cg21905437 chr5:178450457 ZNF879 0.43 4.5 0.37 1.53e-5 Pubertal anthropometrics; TGCT cis rs8017423 0.967 rs8021881 chr14:90722276 T/C cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg15687855 chr3:44754131 ZNF502 0.45 5.36 0.43 3.99e-7 Depressive symptoms; TGCT cis rs12142240 0.698 rs56063031 chr1:46825433 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs4891159 0.548 rs689902 chr18:74119969 C/T cg24786174 chr18:74118243 ZNF516 -0.7 -15.58 -0.81 5.53e-31 Longevity; TGCT cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 14.32 0.79 4.83e-28 Prudent dietary pattern; TGCT cis rs2797160 0.874 rs58305111 chr6:126008386 G/T cg05901451 chr6:126070800 HEY2 0.75 6.33 0.49 4.14e-9 Endometrial cancer; TGCT cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg03396347 chr1:1875803 NA -0.37 -6.68 -0.51 7.07e-10 Body mass index; TGCT cis rs617791 0.508 rs747526 chr11:65776071 C/A cg09783858 chr11:65769428 EIF1AD;BANF1 0.49 4.49 0.37 1.64e-5 Breast cancer; TGCT cis rs1153858 1.000 rs8032904 chr15:45651309 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs644799 1.000 rs680134 chr11:95559517 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9926296 0.568 rs417323 chr16:89746277 T/G cg01097406 chr16:89675127 NA 0.33 5.79 0.46 5.55e-8 Vitiligo; TGCT cis rs1577917 0.958 rs10944144 chr6:86537755 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.46 -0.44 2.47e-7 Response to antipsychotic treatment; TGCT cis rs2439831 0.702 rs7171750 chr15:44025858 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg11502198 chr6:26597334 ABT1 0.54 4.95 0.41 2.42e-6 Intelligence (multi-trait analysis); TGCT cis rs597539 0.689 rs596874 chr11:68630874 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.86 -8.18 -0.59 2.9e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6088590 0.561 rs3891369 chr20:33161127 C/T cg08999081 chr20:33150536 PIGU 0.25 4.73 0.39 5.91e-6 Coronary artery disease; TGCT cis rs28374715 0.510 rs28478807 chr15:41558620 G/T cg18705301 chr15:41695430 NDUFAF1 -0.65 -7.85 -0.58 1.65e-12 Ulcerative colitis; TGCT cis rs910187 0.605 rs6018324 chr20:45810181 G/C cg27589058 chr20:45804311 EYA2 -0.38 -8.34 -0.6 1.18e-13 Migraine; TGCT cis rs35000415 0.938 rs12539476 chr7:128657483 T/C cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT trans rs1496653 0.602 rs35314441 chr3:23454217 C/T cg02770683 chr12:57597238 LRP1 0.38 6.77 0.52 4.52e-10 Type 2 diabetes; TGCT cis rs6589563 0.737 rs11823543 chr11:116649135 G/A cg20660624 chr11:117307972 DSCAML1 -0.36 -4.7 -0.39 6.66e-6 Eosinophil counts; TGCT cis rs72615157 0.634 rs2272343 chr7:99778285 A/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.64 5.1 0.42 1.26e-6 Lung function (FEV1/FVC); TGCT cis rs7000551 0.505 rs4872499 chr8:22293306 A/G cg12081754 chr8:22256438 SLC39A14 -0.39 -5.04 -0.41 1.61e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs597539 0.652 rs686390 chr11:68656077 T/C cg04772025 chr11:68637568 NA 0.6 6.7 0.52 6.37e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7727544 0.660 rs2631361 chr5:131707380 C/A cg24060327 chr5:131705240 SLC22A5 0.62 6.77 0.52 4.69e-10 Blood metabolite levels; TGCT cis rs59104589 0.916 rs62193162 chr2:242268436 T/A cg21155796 chr2:242212141 HDLBP 0.56 4.77 0.39 5.12e-6 Fibrinogen levels; TGCT cis rs6121246 0.909 rs6058460 chr20:30363071 G/A cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs8062405 1.000 rs7198606 chr16:28875122 T/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg11845111 chr2:191398756 TMEM194B -0.36 -5.44 -0.44 2.73e-7 Pulse pressure; TGCT cis rs631288 0.557 rs6697092 chr1:146659277 C/G cg25205988 chr1:146714368 CHD1L 1.34 5.37 0.43 3.79e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs9993613 0.875 rs1401144 chr4:73506817 G/A cg15102770 chr4:73434591 ADAMTS3 0.51 4.7 0.39 6.8e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs73001065 0.591 rs57962361 chr19:19425025 C/T cg03709012 chr19:19516395 GATAD2A 0.87 4.59 0.38 1.09e-5 LDL cholesterol; TGCT cis rs921968 0.643 rs589967 chr2:219445165 T/C cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs752010 0.715 rs4660551 chr1:42099979 T/C cg06885757 chr1:42089581 HIVEP3 0.28 4.91 0.4 2.79e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs12579753 0.872 rs34415838 chr12:82122078 T/C cg07988820 chr12:82153109 PPFIA2 -0.67 -7.34 -0.55 2.5e-11 Resting heart rate; TGCT cis rs6746896 1.000 rs6746896 chr2:97410949 C/T cg26085987 chr2:97230376 NA -0.18 -4.56 -0.38 1.2e-5 Bipolar disorder; TGCT cis rs57590327 0.503 rs898763 chr3:81513408 T/C cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs9325144 0.600 rs7312522 chr12:38730423 A/G cg26384229 chr12:38710491 ALG10B 0.61 5.58 0.45 1.45e-7 Morning vs. evening chronotype; TGCT cis rs7568458 0.846 rs6738645 chr2:85783128 T/G cg02493740 chr2:85810744 VAMP5 -0.29 -5.59 -0.45 1.35e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg10819733 chr22:24237672 NA -0.32 -5.37 -0.43 3.78e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs4332037 0.624 rs56256289 chr7:1892529 C/T cg25206134 chr2:45395956 NA 0.92 7.87 0.58 1.52e-12 Bipolar disorder; TGCT cis rs6938 0.596 rs11630918 chr15:75155896 C/T cg10253484 chr15:75165896 SCAMP2 -0.61 -5.46 -0.44 2.45e-7 Breast cancer; TGCT cis rs2201728 0.967 rs3749550 chr4:100221503 C/T cg07219303 chr4:100140905 ADH6 -0.35 -5.14 -0.42 1.04e-6 Cardiac Troponin-T levels; TGCT cis rs8177253 0.965 rs4854761 chr3:133498789 A/G cg11941060 chr3:133502564 NA 0.29 6.25 0.49 6.15e-9 Iron status biomarkers; TGCT cis rs12510870 0.599 rs16849677 chr4:74452188 T/C cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs6121246 0.697 rs7269866 chr20:30232504 G/A cg13852791 chr20:30311386 BCL2L1 0.74 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin; TGCT cis rs7666738 0.830 rs957742 chr4:99029409 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7590720 1.000 rs934154 chr2:216901933 C/T cg12620499 chr2:216877984 MREG 0.85 8.48 0.61 5.57e-14 Alcohol dependence; TGCT cis rs7727544 0.735 rs272860 chr5:131684175 C/G cg24060327 chr5:131705240 SLC22A5 -0.56 -6.26 -0.49 5.61e-9 Blood metabolite levels; TGCT cis rs7772486 0.790 rs4280983 chr6:146280790 G/C cg23711669 chr6:146136114 FBXO30 -0.88 -10.07 -0.67 8.66e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs986417 0.818 rs1955702 chr14:61074301 T/A cg27398547 chr14:60952738 C14orf39 1.33 9.79 0.66 4e-17 Gut microbiota (bacterial taxa); TGCT cis rs61990749 0.544 rs176979 chr14:78198072 A/C cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs6912958 0.677 rs111990232 chr6:88022240 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.53 4.69 0.39 7.17e-6 Monocyte percentage of white cells; TGCT cis rs1577917 0.739 rs2758846 chr6:86349570 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.57 -0.45 1.5e-7 Response to antipsychotic treatment; TGCT trans rs621559 0.636 rs620418 chr1:43671182 A/G cg19324027 chr2:74699582 MRPL53 0.87 6.75 0.52 5.12e-10 Telomere length; TGCT cis rs9969804 0.846 rs912260 chr9:95493279 C/G cg13940029 chr9:95239186 CENPP;ASPN -0.17 -4.48 -0.37 1.67e-5 Height; TGCT cis rs11148252 0.532 rs9536262 chr13:53303074 A/C cg00495681 chr13:53174319 NA -0.78 -8.2 -0.59 2.53e-13 Lewy body disease; TGCT cis rs17445774 0.857 rs6435043 chr2:200900974 C/G cg17644776 chr2:200775616 C2orf69 0.3 4.77 0.39 5.17e-6 LDL cholesterol to HDL cholesterol ratio; TGCT cis rs9393777 0.513 rs1104871 chr6:26665235 T/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.84 -0.46 4.22e-8 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.593 rs1877186 chr4:152692418 C/G cg17479576 chr4:152424074 FAM160A1 -0.53 -5.26 -0.43 5.99e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs4292341 chr4:98959724 C/T cg05340658 chr4:99064831 C4orf37 0.55 6.07 0.48 1.47e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs67696533 0.957 rs293566 chr20:31097877 T/C cg25191716 chr20:32077802 CBFA2T2 -0.5 -4.43 -0.37 2.01e-5 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs362296 0.661 rs3095077 chr4:3265710 A/G cg06533319 chr4:3265114 C4orf44 -0.25 -5.0 -0.41 1.95e-6 Parental longevity (mother's age at death); TGCT cis rs116095464 0.558 rs56298907 chr5:283280 C/A cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT cis rs11754661 1.000 rs78944278 chr6:151207454 C/T cg11579907 chr6:151412213 MTHFD1L 0.54 4.91 0.4 2.83e-6 Alzheimer's disease (late onset); TGCT cis rs17253792 0.822 rs75437558 chr14:56066798 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs1629083 0.905 rs17121881 chr11:118081345 A/T cg16594165 chr11:118135105 MPZL2 -0.33 -4.59 -0.38 1.09e-5 Lung cancer; TGCT cis rs9486719 0.857 rs2971609 chr6:97039665 A/G cg06623918 chr6:96969491 KIAA0776 -1.04 -10.25 -0.68 3.11e-18 Migraine;Coronary artery disease; TGCT cis rs10504229 0.906 rs2270608 chr8:58194688 T/C cg21724239 chr8:58056113 NA 0.38 4.7 0.39 6.91e-6 Developmental language disorder (linguistic errors); TGCT cis rs3733585 0.726 rs4306953 chr4:9955776 G/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8084125 0.832 rs62105180 chr18:74951197 C/G cg07390210 chr18:74961196 GALR1 0.37 4.51 0.38 1.49e-5 Obesity-related traits; TGCT trans rs916888 0.821 rs70600 chr17:44860021 C/T cg07870213 chr5:140052090 DND1 0.62 7.4 0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs9291683 0.526 rs7695555 chr4:10001656 T/C cg00071950 chr4:10020882 SLC2A9 0.68 8.18 0.59 2.85e-13 Bone mineral density; TGCT trans rs7615952 0.800 rs2062773 chr3:125639648 T/C cg07211511 chr3:129823064 LOC729375 -0.46 -7.9 -0.58 1.26e-12 Blood pressure (smoking interaction); TGCT cis rs1005224 0.654 rs8005753 chr14:76136086 A/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.65 -5.88 -0.47 3.49e-8 Large artery stroke; TGCT cis rs7914558 0.933 rs1538204 chr10:104733893 T/A cg15744005 chr10:104629667 AS3MT -0.4 -4.97 -0.41 2.21e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg00343986 chr7:65444356 GUSB 0.26 6.06 0.48 1.48e-8 Aortic root size; TGCT cis rs11673344 0.523 rs2082009 chr19:37530736 T/G cg08039142 chr19:36980659 ZNF566 0.5 4.65 0.39 8.42e-6 Obesity-related traits; TGCT cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg04744514 chr10:134541379 INPP5A 0.25 4.49 0.37 1.58e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs801193 0.569 rs3846973 chr7:66120035 T/C cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs682748 0.782 rs12187273 chr5:17110554 A/G cg23987134 chr5:17158319 LOC285696 -0.21 -4.9 -0.4 2.87e-6 Hippocampal atrophy; TGCT cis rs26868 1.000 rs26870 chr16:2248229 C/A cg26873644 chr16:2260806 C16orf79 -0.23 -4.48 -0.37 1.69e-5 Height; TGCT cis rs78487399 0.808 rs7556744 chr2:43672795 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.44 5.24 0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6582630 0.574 rs12146797 chr12:38436499 T/C cg13010199 chr12:38710504 ALG10B 0.59 4.79 0.4 4.67e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12477438 0.520 rs4851187 chr2:99745860 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.88 -8.83 -0.62 8.54e-15 Chronic sinus infection; TGCT cis rs3733585 0.753 rs12500805 chr4:10017979 C/T cg11266682 chr4:10021025 SLC2A9 0.72 9.87 0.66 2.54e-17 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13242816 1.000 rs6968230 chr7:116137049 G/T cg02799643 chr7:116139180 CAV2 -0.46 -5.92 -0.47 3e-8 P wave duration; TGCT cis rs7267979 0.966 rs2257233 chr20:25265984 A/C cg03522245 chr20:25566470 NINL -0.6 -6.31 -0.49 4.42e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12220898 0.749 rs17009669 chr10:50470109 A/C cg25968469 chr10:49687287 ARHGAP22 -0.28 -4.51 -0.38 1.51e-5 Inflammatory biomarkers; TGCT cis rs10114408 0.959 rs6415865 chr9:96644692 A/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1865760 0.566 rs2794720 chr6:26087202 G/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs1008375 0.864 rs4698196 chr4:17574735 T/C cg16339924 chr4:17578868 LAP3 0.85 7.15 0.54 6.5e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg25767906 chr1:53392781 SCP2 0.47 5.26 0.43 6.03e-7 Monocyte count; TGCT cis rs2070488 0.775 rs13098946 chr3:38517784 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.77 7.53 0.56 9.03e-12 Electrocardiographic conduction measures; TGCT cis rs7822232 0.908 rs4977164 chr8:145144912 T/G cg06239191 chr8:145163136 KIAA1875 -0.88 -6.45 -0.5 2.26e-9 Blood metabolite levels; TGCT cis rs7020830 0.898 rs308521 chr9:37367094 T/C cg14294708 chr9:37120828 ZCCHC7 1.06 13.83 0.78 6.89e-27 Schizophrenia; TGCT cis rs7824557 0.569 rs10106207 chr8:11015338 C/T cg21775007 chr8:11205619 TDH -0.53 -5.01 -0.41 1.84e-6 Retinal vascular caliber; TGCT cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg05738196 chr6:26577821 NA 0.88 11.13 0.71 2.26e-20 Intelligence (multi-trait analysis); TGCT cis rs1903068 0.614 rs9998950 chr4:55996845 C/T cg01777861 chr4:56023843 NA 0.53 5.81 0.46 4.92e-8 Endometriosis; TGCT cis rs5769765 0.908 rs138864 chr22:50204712 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.06 -10.93 -0.7 6.83e-20 Schizophrenia; TGCT cis rs59698941 0.943 rs67860107 chr5:132276825 G/C cg27099455 chr5:132201840 GDF9;UQCRQ 0.37 4.47 0.37 1.74e-5 Apolipoprotein A-IV levels; TGCT cis rs17221829 0.673 rs10830334 chr11:89403921 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 1.93e-5 Anxiety in major depressive disorder; TGCT cis rs7208859 0.623 rs170051 chr17:28914153 G/A cg13385521 chr17:29058706 SUZ12P 0.86 5.14 0.42 1.05e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7772486 0.654 rs1011597 chr6:146075672 A/C cg05347473 chr6:146136440 FBXO30 -0.49 -4.57 -0.38 1.15e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.744 rs6050463 chr20:25208990 G/A cg14121845 chr20:25566513 NINL 0.46 4.67 0.39 7.71e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 0.966 rs2151144 chr20:25414924 G/C cg16686733 chr20:25566563 NINL -0.58 -5.86 -0.47 3.93e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3820928 0.874 rs7594505 chr2:227878562 C/G cg11843606 chr2:227700838 RHBDD1 -0.5 -4.53 -0.38 1.35e-5 Pulmonary function; TGCT cis rs6665290 0.935 rs17600669 chr1:227201871 A/G cg10327440 chr1:227177885 CDC42BPA -1.0 -20.66 -0.88 5.7e-42 Myeloid white cell count; TGCT cis rs9388451 0.874 rs9398787 chr6:126090608 A/G cg05901451 chr6:126070800 HEY2 -1.02 -15.06 -0.8 8.77e-30 Brugada syndrome; TGCT cis rs6121246 0.697 rs8118150 chr20:30436088 G/A cg13852791 chr20:30311386 BCL2L1 0.84 6.17 0.48 8.77e-9 Mean corpuscular hemoglobin; TGCT cis rs7572733 0.534 rs700680 chr2:198707950 A/T cg00792783 chr2:198669748 PLCL1 -0.55 -5.12 -0.42 1.13e-6 Dermatomyositis; TGCT cis rs4566357 0.615 rs2272204 chr2:227915601 G/T cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.92e-7 Coronary artery disease; TGCT trans rs6089829 0.855 rs4809459 chr20:61661345 C/T cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs929354 0.685 rs1808217 chr7:157002741 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.77 -0.62 1.19e-14 Body mass index; TGCT cis rs35146811 0.844 rs12705070 chr7:99656927 A/G cg13334819 chr7:99746414 C7orf59 -0.8 -6.87 -0.52 2.81e-10 Coronary artery disease; TGCT cis rs7666738 0.830 rs11944855 chr4:99068258 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.932 rs6132848 chr20:25561645 C/T cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs981844 1.000 rs55792703 chr4:154668278 C/A cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs7666738 0.830 rs9998582 chr4:98938949 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg03303774 chr4:1407052 NA -0.33 -5.06 -0.41 1.46e-6 Obesity-related traits; TGCT cis rs13256369 0.802 rs11249888 chr8:8564934 T/C cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6430585 0.941 rs6708957 chr2:136520043 C/T cg07169764 chr2:136633963 MCM6 0.89 7.96 0.58 9.17e-13 Corneal structure; TGCT cis rs9921192 0.967 rs233953 chr16:4330570 A/G cg00021532 chr16:4324280 TFAP4 0.83 9.25 0.64 8.07e-16 Prostate-specific antigen levels; TGCT cis rs9486719 1.000 rs12530462 chr6:97053514 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1801251 1.000 rs2044449 chr2:233718808 G/A cg25237894 chr2:233734115 C2orf82 -0.31 -5.47 -0.44 2.38e-7 Coronary artery disease; TGCT cis rs80282103 0.618 rs74120451 chr10:1126866 T/C cg18964960 chr10:1102726 WDR37 0.99 4.44 0.37 2.01e-5 Glomerular filtration rate (creatinine); TGCT cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg05738196 chr6:26577821 NA 0.88 10.63 0.69 3.68e-19 Intelligence (multi-trait analysis); TGCT cis rs362272 0.545 rs2749783 chr4:3326098 A/C cg06533319 chr4:3265114 C4orf44 -0.26 -5.34 -0.43 4.37e-7 Serum sulfate level; TGCT cis rs67311347 0.544 rs12633295 chr3:40335292 G/T cg13683864 chr3:40499215 RPL14 0.79 7.54 0.56 8.54e-12 Renal cell carcinoma; TGCT cis rs6964587 1.000 rs2299239 chr7:91654617 C/T cg17063962 chr7:91808500 NA 0.92 10.19 0.67 4.47e-18 Breast cancer; TGCT cis rs12477438 0.520 rs13009147 chr2:99803998 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs2046867 0.818 rs17010133 chr3:72827987 T/C cg25664220 chr3:72788482 NA -0.56 -6.93 -0.53 2.07e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4862307 0.836 rs6829678 chr4:185001631 C/T cg06737308 chr4:185021514 ENPP6 -0.35 -5.08 -0.42 1.34e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs78456975 1.000 rs6744743 chr2:1558161 C/T cg01028140 chr2:1542097 TPO 0.32 4.52 0.38 1.41e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs12711979 0.765 rs13028529 chr2:3825467 C/T cg17052675 chr2:3827356 NA -0.39 -7.63 -0.57 5.34e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs6969780 0.722 rs4722666 chr7:27197601 C/G cg04317399 chr7:27170313 HOXA4 -0.44 -4.9 -0.4 2.94e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7824557 0.591 rs2736282 chr8:11225480 C/T cg21775007 chr8:11205619 TDH 0.66 6.74 0.52 5.2400000000000005e-10 Retinal vascular caliber; TGCT cis rs9987353 0.544 rs2929469 chr8:9062656 T/G cg06636001 chr8:8085503 FLJ10661 0.48 4.44 0.37 1.96e-5 Recombination measurement; TGCT cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs12464483 0.591 rs2602775 chr2:30883012 C/T cg12454169 chr2:30669597 LCLAT1 0.4 4.68 0.39 7.44e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs10791323 0.598 rs10750550 chr11:133736083 A/G cg15485101 chr11:133734466 NA 0.39 5.61 0.45 1.28e-7 Childhood ear infection; TGCT cis rs1568889 0.838 rs7933991 chr11:28059761 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.21 0.71 1.43e-20 Bipolar disorder; TGCT cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.65 -6.59 -0.51 1.12e-9 Intelligence (multi-trait analysis); TGCT cis rs1857353 1.000 rs17096887 chr1:75903598 T/C cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs6089584 0.888 rs2386555 chr20:60612373 C/T cg16423285 chr20:60520624 NA -0.61 -6.46 -0.5 2.12e-9 Body mass index; TGCT cis rs7914558 1.000 rs10883837 chr10:104896486 G/A cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.66e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs67311347 1.000 rs73080165 chr3:40533062 G/T cg13409248 chr3:40428643 ENTPD3 0.64 4.91 0.4 2.77e-6 Renal cell carcinoma; TGCT cis rs903263 0.965 rs12748859 chr1:84655238 G/A cg09664975 chr1:84543551 PRKACB 0.48 4.54 0.38 1.31e-5 Breast cancer (male); TGCT cis rs2236918 0.710 rs1776174 chr1:242031839 G/T cg04158730 chr1:242011433 EXO1 0.56 5.16 0.42 9.55e-7 Menopause (age at onset); TGCT cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.83 0.4 3.97e-6 Bipolar disorder; TGCT cis rs1008375 1.000 rs10939743 chr4:17662731 G/A cg18681998 chr4:17616180 MED28 0.93 10.91 0.7 7.68e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1048238 0.506 rs848195 chr1:16286522 A/G cg22431228 chr1:16359049 CLCNKA 0.23 4.54 0.38 1.33e-5 Systolic blood pressure; TGCT cis rs709400 0.604 rs7158144 chr14:103887615 A/G cg12935359 chr14:103987150 CKB -0.36 -5.47 -0.44 2.42e-7 Body mass index; TGCT cis rs10465746 0.967 rs5028806 chr1:84329295 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg06634786 chr22:41940651 POLR3H -0.89 -8.16 -0.59 3.16e-13 Vitiligo; TGCT cis rs4919044 0.808 rs835275 chr10:94796683 T/C cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs12908161 1.000 rs34900908 chr15:85257599 G/A cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs7666738 0.830 rs1426670 chr4:98923572 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs798766 1.000 rs798719 chr4:1698183 C/T cg05874882 chr4:1763078 NA -0.39 -5.15 -0.42 9.83e-7 Bladder cancer;Urinary bladder cancer; TGCT cis rs7104764 1.000 rs10794302 chr11:234102 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs10871290 0.881 rs3863439 chr16:74470644 T/C cg01733217 chr16:74700730 RFWD3 -0.6 -5.66 -0.45 1.02e-7 Breast cancer; TGCT cis rs12908161 0.959 rs61074241 chr15:85333396 C/T cg12863693 chr15:85201151 NMB 0.38 4.45 0.37 1.9e-5 Schizophrenia; TGCT cis rs301043 0.500 rs301038 chr12:95877796 C/T cg07805603 chr12:95869602 METAP2 0.41 5.19 0.42 8.35e-7 Immature fraction of reticulocytes; TGCT cis rs7267979 0.586 rs6037057 chr20:25182089 T/C cg03522245 chr20:25566470 NINL 0.5 5.27 0.43 5.88e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9948 0.655 rs62156228 chr2:97420335 A/G cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs832540 0.931 rs33318 chr5:56208414 G/T cg24531977 chr5:56204891 C5orf35 -0.53 -5.49 -0.44 2.15e-7 Coronary artery disease; TGCT cis rs11096990 0.892 rs6815686 chr4:39199791 A/T ch.4.37949012R chr4:38272617 NA -0.38 -4.81 -0.4 4.33e-6 Cognitive function; TGCT cis rs3812049 0.784 rs1560637 chr5:127448066 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.64 5.87 0.47 3.81e-8 Lymphocyte counts;Red cell distribution width; TGCT cis rs3806843 0.547 rs246010 chr5:140336635 A/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs4891159 0.790 rs11872411 chr18:74132051 C/T cg24786174 chr18:74118243 ZNF516 -0.59 -8.89 -0.62 6.07e-15 Longevity; TGCT cis rs9388451 0.872 rs2008027 chr6:126052359 A/G cg05901451 chr6:126070800 HEY2 -1.01 -13.73 -0.78 1.17e-26 Brugada syndrome; TGCT cis rs12762955 0.561 rs4880744 chr10:1012026 A/G cg18964960 chr10:1102726 WDR37 -0.64 -5.66 -0.45 1.01e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs12908161 0.959 rs34028043 chr15:85231585 G/A cg11189052 chr15:85197271 WDR73 0.75 6.3 0.49 4.8e-9 Schizophrenia; TGCT cis rs6598955 0.543 rs17163720 chr1:26549399 A/G cg04990556 chr1:26633338 UBXN11 -0.8 -7.3 -0.55 3.01e-11 Obesity-related traits; TGCT cis rs9929218 0.529 rs8060790 chr16:68729112 A/G cg01251360 chr16:68772225 CDH1 -0.26 -4.87 -0.4 3.33e-6 Colorectal cancer; TGCT cis rs72781680 0.821 rs17045981 chr2:24109316 A/G cg08917208 chr2:24149416 ATAD2B 0.87 5.33 0.43 4.46e-7 Lymphocyte counts; TGCT cis rs1857353 1.000 rs12405357 chr1:75861616 A/T cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7666738 0.518 rs13133925 chr4:98706398 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.76 0.46 6.27e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7943191 0.805 rs12226821 chr11:62369018 C/G cg11742103 chr11:62369870 EML3;MTA2 0.55 6.38 0.5 3.12e-9 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg27286337 chr10:134555280 INPP5A 0.39 4.73 0.39 6.02e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1218582 0.710 rs7553195 chr1:154837796 T/C cg24250549 chr1:154909240 PMVK 0.54 5.08 0.42 1.33e-6 Prostate cancer; TGCT cis rs80282103 0.618 rs74117848 chr10:1160974 T/G cg18964960 chr10:1102726 WDR37 1.03 4.55 0.38 1.28e-5 Glomerular filtration rate (creatinine); TGCT cis rs1030877 0.960 rs3792049 chr2:105901908 A/C cg02079111 chr2:105885981 TGFBRAP1 -0.18 -5.01 -0.41 1.85e-6 Obesity-related traits; TGCT cis rs4478858 0.709 rs7514640 chr1:31752316 G/A cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs1670533 0.932 rs11731289 chr4:1057773 T/G cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs4499344 0.730 rs28402742 chr19:33099734 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs71597109 0.639 rs4698969 chr4:102725955 A/G cg14855874 chr4:102712397 BANK1 -0.42 -5.07 -0.41 1.43e-6 Chronic lymphocytic leukemia; TGCT cis rs11123170 0.503 rs28679654 chr2:113967617 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.56 4.56 0.38 1.21e-5 Renal function-related traits (BUN); TGCT cis rs9486719 1.000 rs2499807 chr6:96864053 T/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs13191362 1.000 rs13204439 chr6:163015358 A/C cg21926612 chr6:163149169 PACRG;PARK2 -0.68 -5.79 -0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs909341 0.537 rs6089971 chr20:62385846 G/A cg14758556 chr20:62440591 NA 0.4 5.74 0.46 6.9e-8 Atopic dermatitis; TGCT cis rs13082711 0.522 rs537674 chr3:27361901 G/T cg02860705 chr3:27208620 NA 0.3 4.96 0.41 2.3e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs597539 0.652 rs559032 chr11:68710847 G/T cg21862992 chr11:68658383 NA 0.45 6.17 0.48 9.06e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs62244186 0.627 rs12386385 chr3:44457540 A/G cg02073558 chr3:44770973 ZNF501 0.6 5.79 0.46 5.35e-8 Depressive symptoms; TGCT cis rs7666738 0.830 rs4699577 chr4:98846513 G/A cg17366294 chr4:99064904 C4orf37 0.72 7.56 0.56 7.78e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7727544 0.716 rs4705926 chr5:131561758 C/T cg21474247 chr5:131268130 NA 0.32 4.54 0.38 1.32e-5 Blood metabolite levels; TGCT cis rs3008870 0.959 rs2985810 chr1:67376162 T/C cg03991309 chr1:68237761 GNG12 0.27 4.68 0.39 7.28e-6 Lymphocyte percentage of white cells; TGCT cis rs6964587 0.839 rs6950538 chr7:91417816 T/C cg17063962 chr7:91808500 NA 0.84 8.25 0.6 1.99e-13 Breast cancer; TGCT cis rs11671005 0.735 rs11878198 chr19:58920302 A/G cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT cis rs35146811 0.695 rs1618851 chr7:99810643 T/G cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs11722228 1.000 rs11722228 chr4:9915741 C/T cg11266682 chr4:10021025 SLC2A9 0.46 5.12 0.42 1.11e-6 Gout;Urate levels;Serum uric acid levels; TGCT cis rs7666738 0.571 rs7683769 chr4:99091742 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.75 0.39 5.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3806843 0.576 rs246046 chr5:140329264 T/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs2404602 0.611 rs2404734 chr15:76936165 T/C cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs9467773 1.000 rs9467783 chr6:26542894 C/T cg15659132 chr6:26577336 NA 0.85 12.04 0.73 1.38e-22 Intelligence (multi-trait analysis); TGCT cis rs244731 0.959 rs7724098 chr5:176659570 G/A cg17509989 chr5:176798049 RGS14 -0.62 -7.54 -0.56 8.56e-12 Urate levels in lean individuals; TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg26354017 chr1:205819088 PM20D1 0.54 6.39 0.5 3.1e-9 Menarche (age at onset); TGCT cis rs938554 0.542 rs7678287 chr4:10000501 A/G cg11266682 chr4:10021025 SLC2A9 0.5 4.53 0.38 1.35e-5 Blood metabolite levels; TGCT cis rs2153535 0.580 rs7341383 chr6:8470634 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6688613 0.545 rs10800270 chr1:166827602 A/T cg07049167 chr1:166818506 POGK 0.24 5.09 0.42 1.31e-6 Refractive astigmatism; TGCT cis rs7192750 0.652 rs152828 chr16:72123886 T/C cg06353428 chr16:71660113 MARVELD3 1.03 5.27 0.43 5.78e-7 LDL cholesterol levels;Total cholesterol levels; TGCT trans rs7618501 0.669 rs7634084 chr3:49949834 A/T cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.26 0.64 7.75e-16 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs4345191 chr4:98945408 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.791 rs952406 chr6:145925616 C/A cg13319975 chr6:146136371 FBXO30 -0.53 -4.79 -0.4 4.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg10117171 chr1:25599238 RHD 0.3 4.93 0.4 2.62e-6 Erythrocyte sedimentation rate; TGCT cis rs9560113 1.000 rs9555806 chr13:112179954 G/A cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs2204008 0.683 rs11522927 chr12:38137537 C/T cg13010199 chr12:38710504 ALG10B 0.67 5.31 0.43 4.83e-7 Bladder cancer; TGCT cis rs10751667 0.621 rs7394862 chr11:927500 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs2249625 0.526 rs17725666 chr6:72889711 G/A cg08500200 chr6:72892038 RIMS1 0.42 4.58 0.38 1.14e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg24675658 chr1:53192096 ZYG11B -0.69 -7.99 -0.58 8.01e-13 Monocyte count; TGCT cis rs4455778 0.538 rs7796590 chr7:49124983 C/T cg26309511 chr7:48887640 NA 0.51 6.62 0.51 9.97e-10 Lung cancer in never smokers; TGCT cis rs854765 0.647 rs4426402 chr17:17977926 C/T cg09796270 chr17:17721594 SREBF1 -0.23 -4.68 -0.39 7.33e-6 Total body bone mineral density; TGCT cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg08280861 chr8:58055591 NA 0.53 5.96 0.47 2.44e-8 Developmental language disorder (linguistic errors); TGCT cis rs2033711 0.503 rs6510141 chr19:58885786 C/G cg13691442 chr19:58878570 NA 0.19 4.59 0.38 1.09e-5 Uric acid clearance; TGCT cis rs6964587 1.000 rs10236397 chr7:91691601 C/T cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs858239 0.738 rs13225593 chr7:23260307 A/G cg05602783 chr7:23145260 KLHL7 -0.66 -5.18 -0.42 8.78e-7 Cerebrospinal fluid biomarker levels; TGCT trans rs2727020 0.563 rs10769582 chr11:49474040 T/C cg15704280 chr7:45808275 SEPT13 -0.75 -8.76 -0.62 1.24e-14 Coronary artery disease; TGCT trans rs4332037 0.707 rs62435130 chr7:1890002 C/T cg10840412 chr1:235813424 GNG4 0.86 6.76 0.52 4.92e-10 Bipolar disorder; TGCT cis rs2797160 0.935 rs1739379 chr6:126012593 T/C cg05901451 chr6:126070800 HEY2 0.74 6.12 0.48 1.15e-8 Endometrial cancer; TGCT cis rs11711311 1.000 rs9851731 chr3:113502651 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.7 6.64 0.51 8.96e-10 IgG glycosylation; TGCT cis rs1062177 0.756 rs2964589 chr5:151118189 G/T cg12924095 chr5:151150029 G3BP1 -0.34 -4.65 -0.39 8.34e-6 Preschool internalizing problems; TGCT cis rs8038465 0.874 rs3816661 chr15:74005600 C/T cg15420318 chr15:73925796 NPTN 0.55 5.08 0.42 1.33e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs950169 0.922 rs8037078 chr15:84818871 A/G cg17173187 chr15:85201210 NMB -0.54 -5.52 -0.44 1.87e-7 Schizophrenia; TGCT cis rs3617 0.625 rs11719137 chr3:52876389 G/T cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs78456975 0.689 rs13391992 chr2:1542153 G/A cg01028140 chr2:1542097 TPO -0.37 -5.3 -0.43 5.13e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs1062177 0.855 rs6892117 chr5:151264985 C/T cg14319409 chr5:151304409 GLRA1 -0.35 -4.45 -0.37 1.85e-5 Preschool internalizing problems; TGCT cis rs7552404 0.727 rs1144336 chr1:76277421 C/A cg22875332 chr1:76189707 ACADM 0.63 6.96 0.53 1.71e-10 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs2840044 0.711 rs225301 chr17:33922411 T/A cg19694781 chr19:47549865 TMEM160 -0.42 -8.04 -0.59 6.07e-13 Response to radiotherapy in cancer (late toxicity); TGCT trans rs941408 1.000 rs1076447 chr19:2792128 C/G cg22153745 chr1:153894579 GATAD2B -0.64 -7.01 -0.53 1.39e-10 Total cholesterol levels; TGCT cis rs1519814 0.654 rs11986190 chr8:121013325 G/A cg22335954 chr8:121166405 COL14A1 -0.36 -4.52 -0.38 1.44e-5 Breast cancer; TGCT cis rs8031584 0.678 rs798127 chr15:31117403 T/C cg14829155 chr15:31115871 NA 0.37 4.93 0.4 2.59e-6 Huntington's disease progression; TGCT cis rs2742417 0.967 rs1883096 chr3:45750015 C/T cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7582180 0.652 rs11678158 chr2:100932297 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 6.03e-6 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs1371867 0.817 rs1660315 chr8:101332956 G/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs3008870 1.000 rs2985818 chr1:67398916 G/A cg03991309 chr1:68237761 GNG12 0.27 4.55 0.38 1.26e-5 Lymphocyte percentage of white cells; TGCT cis rs10267417 0.514 rs2072184 chr7:19748883 A/G cg05791153 chr7:19748676 TWISTNB 1.34 14.14 0.79 1.26e-27 Night sleep phenotypes; TGCT cis rs3784262 0.565 rs1899355 chr15:58286989 C/T cg12031962 chr15:58353849 ALDH1A2 -0.35 -4.94 -0.41 2.47e-6 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4788570 0.566 rs72795881 chr16:71500229 A/G cg06353428 chr16:71660113 MARVELD3 -1.32 -7.86 -0.58 1.6e-12 Intelligence (multi-trait analysis); TGCT cis rs6598955 0.670 rs10902734 chr1:26617923 G/T cg04990556 chr1:26633338 UBXN11 0.89 11.49 0.72 2.99e-21 Obesity-related traits; TGCT cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs11098499 0.663 rs9996501 chr4:120238918 C/A cg09307838 chr4:120376055 NA 0.63 6.22 0.49 7.01e-9 Corneal astigmatism; TGCT cis rs12477438 0.520 rs11678456 chr2:99708237 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs12510870 0.599 rs2091584 chr4:74416512 C/T cg05868023 chr4:75230803 EREG -0.55 -5.06 -0.41 1.48e-6 Iris color (b* coordinate); TGCT cis rs79349575 0.783 rs4793998 chr17:47019899 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT trans rs28735056 0.967 rs8091497 chr18:77632565 G/A cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT cis rs6840360 0.530 rs6839802 chr4:152485834 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.614 rs2293858 chr8:11213881 G/C cg21775007 chr8:11205619 TDH 0.68 6.46 0.5 2.16e-9 Retinal vascular caliber; TGCT cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg06481639 chr22:41940642 POLR3H 0.71 6.43 0.5 2.56e-9 Vitiligo; TGCT cis rs11030122 0.661 rs10767811 chr11:4066398 G/A cg18678763 chr11:4115507 RRM1 -0.45 -5.6 -0.45 1.3e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 -0.47 -4.95 -0.41 2.35e-6 Lymphocyte counts; TGCT cis rs11992162 0.569 rs35283519 chr8:11831661 C/T cg15426459 chr8:11813211 NA -0.42 -5.42 -0.44 3e-7 Monocyte count; TGCT cis rs2932538 0.922 rs36029940 chr1:113106444 T/G cg10983938 chr1:113465962 AFARP1;SLC16A1 0.21 4.44 0.37 1.99e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7267979 1.000 rs2259956 chr20:25282433 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3796352 1.000 rs13058817 chr3:53024139 C/T cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9611565 0.503 rs5751156 chr22:42170025 A/G cg06634786 chr22:41940651 POLR3H 0.85 8.04 0.59 6.06e-13 Vitiligo; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg11494091 chr17:61959527 GH2 -0.61 -14.04 -0.78 2.15e-27 Prudent dietary pattern; TGCT cis rs9928842 0.882 rs6564241 chr16:75263974 T/C cg09066997 chr16:75300724 BCAR1 0.28 4.92 0.4 2.72e-6 Alcoholic chronic pancreatitis; TGCT cis rs7267979 0.844 rs6107027 chr20:25288632 A/G cg16686733 chr20:25566563 NINL 0.52 5.1 0.42 1.24e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2486288 0.656 rs11632752 chr15:45551140 A/G cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs4563143 0.663 rs10417671 chr19:29235335 T/C cg12756686 chr19:29218302 NA 0.67 6.2 0.49 7.59e-9 Methadone dose in opioid dependence; TGCT cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs362272 0.505 rs60208975 chr4:3364530 A/G cg06533319 chr4:3265114 C4orf44 -0.26 -5.29 -0.43 5.35e-7 Serum sulfate level; TGCT trans rs61931739 0.500 rs11053189 chr12:34433455 G/A cg26384229 chr12:38710491 ALG10B 0.74 6.89 0.53 2.46e-10 Morning vs. evening chronotype; TGCT cis rs11122272 0.735 rs2437148 chr1:231513979 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs16958440 0.867 rs58061761 chr18:44686165 T/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs36051895 0.530 rs4425810 chr9:5222208 A/G cg02405213 chr9:5042618 JAK2 -0.63 -8.03 -0.58 6.5e-13 Pediatric autoimmune diseases; TGCT cis rs6545883 0.831 rs9309336 chr2:61763165 T/C cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs7829975 0.806 rs2428 chr8:8641145 C/T cg06636001 chr8:8085503 FLJ10661 0.66 5.59 0.45 1.36e-7 Mood instability; TGCT cis rs7264396 0.635 rs6060688 chr20:34516731 C/G cg04508476 chr20:34239394 CPNE1;RBM12 0.28 4.94 0.41 2.44e-6 Total cholesterol levels; TGCT cis rs1005277 0.579 rs176886 chr10:38403974 C/T cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6500602 0.855 rs2304631 chr16:4475868 A/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.31 0.49 4.45e-9 Schizophrenia; TGCT cis rs10984561 0.881 rs16908421 chr9:122244896 G/A cg14242995 chr9:122249943 NA 0.76 6.5 0.5 1.79e-9 Pulmonary function decline; TGCT cis rs1322512 0.848 rs2695247 chr6:152948596 G/T cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs6684514 1.000 rs2277871 chr1:156246742 A/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs71597109 0.639 rs34851381 chr4:102729463 T/C cg14855874 chr4:102712397 BANK1 0.42 4.63 0.38 9.15e-6 Chronic lymphocytic leukemia; TGCT cis rs939658 0.805 rs939661 chr15:79431063 A/G cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs7681440 0.904 rs1372521 chr4:90765223 G/A cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs589448 0.933 rs2249093 chr12:69753512 G/C cg20891283 chr12:69753455 YEATS4 0.91 10.33 0.68 1.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs4730250 0.707 rs3729876 chr7:106786952 T/C cg02696742 chr7:106810147 HBP1 0.74 6.15 0.48 9.79e-9 Osteoarthritis; TGCT cis rs2997447 0.706 rs61776573 chr1:26429356 A/C cg03844060 chr1:26490628 NA 0.26 4.44 0.37 1.96e-5 QRS complex (12-leadsum); TGCT cis rs6684514 0.506 rs3762281 chr1:156304782 A/G cg20302342 chr1:156215951 PAQR6 0.37 5.54 0.45 1.73e-7 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs17376456 0.825 rs36042718 chr5:93180997 C/T cg21475434 chr5:93447410 FAM172A 0.69 4.81 0.4 4.36e-6 Diabetic retinopathy; TGCT cis rs13242816 1.000 rs2188243 chr7:116109293 G/A cg02799643 chr7:116139180 CAV2 -0.48 -5.45 -0.44 2.56e-7 P wave duration; TGCT cis rs68170813 0.599 rs11769901 chr7:106958505 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs7727544 0.526 rs4705908 chr5:131347520 G/A cg21474247 chr5:131268130 NA 0.36 4.85 0.4 3.68e-6 Blood metabolite levels; TGCT cis rs9399137 0.507 rs7761964 chr6:135314265 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.84 0.52 3.14e-10 Electroencephalogram traits; TGCT cis rs9653442 0.777 rs6732141 chr2:100743492 G/C cg22139774 chr2:100720529 AFF3 -0.44 -7.6 -0.56 6.3e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs523522 0.962 rs3893104 chr12:120903936 G/A cg12219531 chr12:120966889 COQ5 0.83 7.3 0.55 2.97e-11 High light scatter reticulocyte count; TGCT cis rs6424115 1.000 rs1018396 chr1:24133612 G/A cg15997130 chr1:24165203 NA 0.89 9.94 0.67 1.81e-17 Immature fraction of reticulocytes; TGCT cis rs9916302 0.904 rs12600751 chr17:37553651 G/C cg07936489 chr17:37558343 FBXL20 0.64 4.81 0.4 4.3e-6 Glomerular filtration rate (creatinine); TGCT cis rs17376456 0.569 rs35878747 chr5:93094070 C/A cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs1008375 0.932 rs4698650 chr4:17692878 G/C cg18681998 chr4:17616180 MED28 0.76 7.28 0.55 3.42e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7264396 0.635 rs6060656 chr20:34466382 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs2996428 0.667 rs7545274 chr1:3744261 G/T cg17848003 chr1:3704513 LRRC47 0.17 4.75 0.39 5.54e-6 Red cell distribution width; TGCT cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg09436375 chr6:42928200 GNMT -0.42 -5.41 -0.44 3.16e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs881375 0.967 rs1930780 chr9:123686219 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.4 4.58 0.38 1.12e-5 Rheumatoid arthritis; TGCT cis rs11711311 0.712 rs4682139 chr3:113331859 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.58 -4.74 -0.39 5.66e-6 IgG glycosylation; TGCT cis rs514406 0.679 rs960570 chr1:53237763 A/G cg08859206 chr1:53392774 SCP2 0.46 7.05 0.53 1.1e-10 Monocyte count; TGCT cis rs910316 1.000 rs7303 chr14:75520065 T/C cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs751728 0.664 rs9394167 chr6:33754396 A/G cg13859433 chr6:33739653 LEMD2 -0.33 -5.75 -0.46 6.65e-8 Crohn's disease; TGCT cis rs10540 1.000 rs61876339 chr11:495283 T/C cg03352830 chr11:487213 PTDSS2 0.26 4.46 0.37 1.8e-5 Body mass index; TGCT cis rs8141529 0.748 rs132531 chr22:29297365 C/T cg02153584 chr22:29168773 CCDC117 -0.64 -5.08 -0.41 1.36e-6 Lymphocyte counts; TGCT cis rs12510870 0.544 rs72647083 chr4:74384981 G/A cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT trans rs7726839 0.540 rs3749615 chr5:601485 C/T cg25482853 chr8:67687455 SGK3 1.23 10.7 0.69 2.49e-19 Obesity-related traits; TGCT cis rs4919694 0.667 rs75890466 chr10:105076383 C/T cg04362960 chr10:104952993 NT5C2 0.94 6.15 0.48 9.68e-9 Arsenic metabolism; TGCT cis rs13191362 1.000 rs73035021 chr6:163000716 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28595532 0.764 rs115986119 chr4:119767785 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs4727027 0.901 rs7794500 chr7:148819519 C/T cg23583168 chr7:148888333 NA 0.72 9.17 0.64 1.3e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs259282 0.692 rs35972270 chr19:33128457 C/T cg26639809 chr19:33781782 NA 0.27 5.74 0.46 6.86e-8 Schizophrenia; TGCT cis rs654950 0.934 rs665223 chr1:42000654 A/T cg06885757 chr1:42089581 HIVEP3 -0.29 -4.96 -0.41 2.22e-6 Airway imaging phenotypes; TGCT cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg26338869 chr17:61819248 STRADA 0.54 5.17 0.42 8.94e-7 Prudent dietary pattern; TGCT cis rs7666738 0.791 rs13149968 chr4:99070262 G/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg24846343 chr22:24311635 DDTL 0.23 6.0 0.47 2.01e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12908161 1.000 rs35960805 chr15:85343980 T/G cg12863693 chr15:85201151 NMB 0.42 5.06 0.41 1.5e-6 Schizophrenia; TGCT cis rs10754283 0.967 rs4658307 chr1:90117586 G/T cg03145924 chr1:90228473 NA -0.4 -4.51 -0.38 1.51e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1018836 0.527 rs13268721 chr8:91481549 G/A cg16814680 chr8:91681699 NA -0.89 -8.99 -0.63 3.52e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs35160687 0.901 rs6714362 chr2:86476588 A/G cg03171300 chr2:86307199 POLR1A -0.31 -5.43 -0.44 2.92e-7 Night sleep phenotypes; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg07167872 chr1:205819463 PM20D1 0.71 10.34 0.68 1.9e-18 Menarche (age at onset); TGCT cis rs916888 0.821 rs70602 chr17:44859715 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs117785887 0.536 rs3811105 chr6:146349751 A/G cg06708562 chr6:146285465 SHPRH -0.85 -5.12 -0.42 1.13e-6 Interleukin-17 levels; TGCT cis rs858239 0.539 rs7791200 chr7:23182121 A/T cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs929843 1 rs929843 chr16:70045748 A/C cg05523882 chr16:70323915 AARS 0.23 4.54 0.38 1.29e-5 Menarche (age at onset); TGCT cis rs6714710 0.603 rs11680321 chr2:98379267 C/T cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg07061783 chr6:25882402 NA 0.64 6.7 0.52 6.57e-10 Blood metabolite levels; TGCT cis rs2836974 0.666 rs1888487 chr21:40683259 A/G cg17971929 chr21:40555470 PSMG1 -0.72 -6.55 -0.51 1.35e-9 Cognitive function; TGCT cis rs12220898 0.749 rs2377976 chr10:50479493 A/G cg09603381 chr10:49954066 WDFY4 0.39 4.73 0.39 6.01e-6 Inflammatory biomarkers; TGCT cis rs2404602 0.716 rs3866543 chr15:76629609 T/G cg22467129 chr15:76604101 ETFA -0.6 -7.44 -0.56 1.45e-11 Blood metabolite levels; TGCT cis rs10769945 0.679 rs2137322 chr11:1917354 A/G cg08273750 chr11:2011282 LOC100133545 -0.27 -4.52 -0.38 1.44e-5 DNA methylation (variation); TGCT cis rs7666738 0.791 rs1405766 chr4:98965389 T/C cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs981844 0.775 rs921884 chr4:154753059 G/A cg14289246 chr4:154710475 SFRP2 -0.96 -8.4 -0.6 8.66e-14 Response to statins (LDL cholesterol change); TGCT cis rs6089829 0.962 rs6011544 chr20:61658782 T/C cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg07332563 chr6:291687 DUSP22 -0.75 -7.74 -0.57 3.04e-12 Menopause (age at onset); TGCT cis rs8141529 0.702 rs469990 chr22:29304200 A/T cg02153584 chr22:29168773 CCDC117 0.59 4.49 0.37 1.6e-5 Lymphocyte counts; TGCT cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.95 9.75 0.66 5.01e-17 Intelligence (multi-trait analysis); TGCT trans rs17685 0.753 rs4732595 chr7:75755139 A/G cg19862616 chr7:65841803 NCRNA00174 0.53 9.11 0.63 1.74e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs116095464 0.558 rs3213838 chr5:223890 G/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs6424115 1.000 rs12121387 chr1:24166536 T/G cg15997130 chr1:24165203 NA -0.92 -10.48 -0.69 8.6e-19 Immature fraction of reticulocytes; TGCT cis rs910187 0.678 rs6018329 chr20:45813184 A/G cg27589058 chr20:45804311 EYA2 -0.36 -7.88 -0.58 1.44e-12 Migraine; TGCT cis rs4478037 0.818 rs17522946 chr3:33138777 A/G cg19404215 chr3:33155277 CRTAP 1.03 5.15 0.42 9.76e-7 Major depressive disorder; TGCT cis rs4727027 0.704 rs10952805 chr7:148907849 G/A cg23583168 chr7:148888333 NA -0.85 -10.95 -0.7 6.08e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs546131 0.928 rs552868 chr11:34830694 G/A cg11058730 chr11:34937778 PDHX;APIP 0.53 4.59 0.38 1.08e-5 Lung disease severity in cystic fibrosis; TGCT cis rs6674176 0.569 rs34830883 chr1:44405339 T/C cg12908607 chr1:44402522 ARTN -0.75 -9.11 -0.63 1.81e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs35000415 0.938 rs35188261 chr7:128683539 G/A cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg10117171 chr1:25599238 RHD -0.32 -5.22 -0.42 7.32e-7 Erythrocyte sedimentation rate; TGCT cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg10207240 chr12:122356781 WDR66 0.35 4.9 0.4 2.97e-6 Mean corpuscular volume; TGCT cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg00149659 chr3:10157352 C3orf10 0.94 6.0 0.47 2e-8 Alzheimer's disease; TGCT cis rs12368653 0.840 rs3816896 chr12:58195773 C/T cg12615879 chr12:58013172 SLC26A10 0.5 5.99 0.47 2.16e-8 Multiple sclerosis; TGCT cis rs10479542 0.806 rs4700835 chr5:178976313 A/G cg19626725 chr5:178986131 RUFY1 0.44 5.46 0.44 2.49e-7 Lung cancer; TGCT cis rs9467773 0.595 rs3846845 chr6:26444915 G/A cg15659132 chr6:26577336 NA -0.43 -4.51 -0.38 1.47e-5 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.921 rs8137373 chr22:41729216 A/G cg06481639 chr22:41940642 POLR3H 0.54 4.72 0.39 6.29e-6 Vitiligo; TGCT cis rs9467711 0.516 rs548987 chr6:25869371 C/G cg12310025 chr6:25882481 NA -0.67 -4.47 -0.37 1.74e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs295137 0.836 rs1217456 chr2:201092279 C/T cg23649088 chr2:200775458 C2orf69 0.35 6.17 0.48 8.75e-9 Asthma (bronchodilator response); TGCT trans rs877282 0.755 rs2486578 chr10:785227 C/T cg22713356 chr15:30763199 NA -0.95 -8.2 -0.59 2.51e-13 Uric acid levels; TGCT cis rs8072100 0.745 rs7214410 chr17:45422628 A/G cg08085267 chr17:45401833 C17orf57 -0.46 -5.19 -0.42 8.36e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6089829 0.692 rs6122349 chr20:61664096 T/C cg08564027 chr20:61660810 NA 0.3 4.71 0.39 6.64e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.36 -4.58 -0.38 1.11e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6882046 0.513 rs34316 chr5:88015545 A/C cg22951263 chr5:87985283 NA -0.57 -6.08 -0.48 1.38e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs6582630 0.502 rs11520278 chr12:38359642 T/A cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.87e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs10791323 0.593 rs2282604 chr11:133714672 A/G cg03690763 chr11:133734501 NA -0.32 -5.42 -0.44 2.94e-7 Childhood ear infection; TGCT cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg17054783 chr10:134559939 INPP5A 0.26 4.93 0.41 2.53e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs73058052 0.597 rs2890072 chr19:50087876 T/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.67 5.46 0.44 2.53e-7 Fibrinogen levels; TGCT cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs2070488 1.000 rs13079757 chr3:38491444 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs5750830 0.649 rs5750808 chr22:39790987 G/A cg01416388 chr22:39784598 NA -0.72 -7.05 -0.53 1.1e-10 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.607 rs132792 chr22:42062822 C/T cg06634786 chr22:41940651 POLR3H 0.81 7.67 0.57 4.44e-12 Vitiligo; TGCT cis rs2836974 0.932 rs8129416 chr21:40617145 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.47 0.5 2.08e-9 Cognitive function; TGCT cis rs72781680 0.898 rs12620558 chr2:23936022 G/A cg08917208 chr2:24149416 ATAD2B 0.89 5.41 0.44 3.11e-7 Lymphocyte counts; TGCT cis rs526231 0.578 rs3776870 chr5:102295070 G/A cg23492399 chr5:102201601 PAM -0.51 -4.48 -0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs1215050 0.791 rs165254 chr4:98763564 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2153535 0.606 rs11243253 chr6:8380193 T/C cg07606381 chr6:8435919 SLC35B3 -0.54 -5.08 -0.42 1.32e-6 Motion sickness; TGCT cis rs9467773 0.967 rs6932865 chr6:26540166 C/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs2180341 1.000 rs4895822 chr6:127642703 T/C cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs933688 1.000 rs12651840 chr5:90729592 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 9.6 0.65 1.2e-16 Smoking behavior; TGCT cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg18230493 chr5:56204884 C5orf35 -0.65 -5.7 -0.46 8.13e-8 Initial pursuit acceleration; TGCT trans rs1814175 0.817 rs1988416 chr11:49932324 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs858239 0.600 rs6978827 chr7:23125544 A/T cg05602783 chr7:23145260 KLHL7 -0.64 -5.37 -0.43 3.69e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10206020 0.885 rs13411553 chr2:1574018 A/G cg01028140 chr2:1542097 TPO -0.28 -4.45 -0.37 1.88e-5 IgG glycosylation; TGCT cis rs778371 0.697 rs2344613 chr2:233603065 C/G cg08000102 chr2:233561755 GIGYF2 0.69 7.77 0.57 2.62e-12 Schizophrenia; TGCT cis rs10892173 0.566 rs2298649 chr11:117672225 A/G cg21014159 chr11:117668035 DSCAML1 0.61 5.86 0.47 3.96e-8 Myopia; TGCT cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs360798 0.553 rs11682530 chr2:63073194 C/T cg17519650 chr2:63277830 OTX1 -0.54 -4.69 -0.39 7.09e-6 Coronary artery disease; TGCT cis rs6701037 0.555 rs10912899 chr1:175120715 C/T cg08873628 chr1:175162347 KIAA0040 0.46 4.75 0.39 5.44e-6 Alcohol dependence; TGCT cis rs7662987 0.517 rs2924580 chr4:100032168 C/G cg12011299 chr4:100065546 ADH4 0.4 4.85 0.4 3.55e-6 Smoking initiation; TGCT cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs2769264 0.546 rs12071705 chr1:151430504 G/C cg18801370 chr1:151430492 POGZ 0.72 6.74 0.52 5.31e-10 Blood trace element (Cu levels); TGCT cis rs12477438 0.798 rs6712338 chr2:99585457 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg08627397 chr16:89984028 MC1R -0.31 -4.8 -0.4 4.46e-6 Vitiligo; TGCT cis rs8180040 0.764 rs11716539 chr3:47186503 G/T cg27129171 chr3:47204927 SETD2 0.77 9.86 0.66 2.77e-17 Colorectal cancer; TGCT cis rs751728 1.000 rs2395449 chr6:33728755 T/A cg13859433 chr6:33739653 LEMD2 -0.39 -7.29 -0.55 3.17e-11 Crohn's disease; TGCT cis rs6586163 0.546 rs12359362 chr10:90753145 G/C cg03111039 chr10:90751583 FAS;ACTA2 0.6 7.77 0.57 2.59e-12 Chronic lymphocytic leukemia; TGCT cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg03517284 chr6:25882590 NA -0.61 -5.5 -0.44 2.12e-7 Intelligence (multi-trait analysis); TGCT cis rs763121 0.853 rs5750621 chr22:38956166 C/T cg06022373 chr22:39101656 GTPBP1 0.81 7.86 0.58 1.58e-12 Menopause (age at onset); TGCT cis rs7267979 1.000 rs2424704 chr20:25273929 A/G cg14121845 chr20:25566513 NINL 0.49 5.23 0.42 7.08e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.761 rs13136913 chr4:98998031 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs1832101 chr6:8460177 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10882165 0.779 rs17382342 chr10:94908144 A/C cg15980076 chr10:94822747 CYP26C1 0.44 4.77 0.39 5.13e-6 Refractive error; TGCT cis rs7772486 0.875 rs6938972 chr6:146410608 G/A cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs13177918 0.677 rs13160685 chr5:149822331 A/G cg14059543 chr5:149831962 NA -0.72 -9.49 -0.65 2.17e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2836633 0.895 rs2836598 chr21:40024758 C/G cg05519781 chr21:40033154 ERG 0.68 6.65 0.51 8.34e-10 Coronary artery disease; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg02675527 chr2:114030824 PAX8;LOC440839 -0.5 -6.65 -0.51 8.34e-10 Lymphocyte counts; TGCT cis rs6460942 1.000 rs7796485 chr7:12405676 G/A cg06484146 chr7:12443880 VWDE -0.63 -5.65 -0.45 1.04e-7 Coronary artery disease; TGCT cis rs13191362 0.872 rs13215538 chr6:163037975 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.92 7.24 0.55 4.11e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3780378 0.682 rs7861755 chr9:5273180 C/T cg02405213 chr9:5042618 JAK2 -0.54 -6.96 -0.53 1.75e-10 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7607369 0.748 rs662250 chr2:219374117 T/A cg02176678 chr2:219576539 TTLL4 0.46 6.31 0.49 4.53e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs727505 0.954 rs59673207 chr7:124596982 G/C cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT trans rs4332037 0.901 rs11767040 chr7:1945468 C/T cg25206134 chr2:45395956 NA 1.1 9.31 0.64 5.82e-16 Bipolar disorder; TGCT cis rs7267979 0.903 rs6115118 chr20:25246734 G/A cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.33 0.55 2.59e-11 Prudent dietary pattern; TGCT cis rs68170813 0.605 rs2299428 chr7:107134384 A/G cg02696742 chr7:106810147 HBP1 -0.64 -5.01 -0.41 1.83e-6 Coronary artery disease; TGCT cis rs4689388 0.824 rs114669221 chr4:6301459 G/A cg25554036 chr4:6271136 WFS1 0.52 7.07 0.54 9.88e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs72945132 0.882 rs72949078 chr11:70217708 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.21 0.54 4.95e-11 Coronary artery disease; TGCT cis rs793571 0.544 rs11638244 chr15:58907151 A/T cg05156742 chr15:59063176 FAM63B 0.56 5.31 0.43 4.86e-7 Schizophrenia; TGCT cis rs7523273 1.000 rs12123251 chr1:207992546 G/A cg22525895 chr1:207977042 MIR29B2 -0.49 -8.55 -0.61 3.78e-14 Schizophrenia; TGCT cis rs35146811 0.844 rs13232115 chr7:99670932 T/C cg13334819 chr7:99746414 C7orf59 -0.74 -6.1 -0.48 1.23e-8 Coronary artery disease; TGCT cis rs9393777 0.778 rs13212921 chr6:27205422 C/T cg10876282 chr6:28092338 ZSCAN16 0.71 4.62 0.38 9.6e-6 Intelligence (multi-trait analysis); TGCT trans rs4957048 0.577 rs56294732 chr5:568144 T/C cg25482853 chr8:67687455 SGK3 1.1 8.74 0.62 1.34e-14 Ulcerative colitis; TGCT cis rs4149423 1.000 rs4149423 chr2:108916044 A/G cg13968390 chr2:108904812 SULT1C2 -0.25 -4.72 -0.39 6.2e-6 Lobe size; TGCT cis rs1538970 0.924 rs12097497 chr1:45880669 C/T cg05343316 chr1:45956843 TESK2 0.73 5.87 0.47 3.79e-8 Platelet count; TGCT cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs7267979 0.934 rs6037085 chr20:25305202 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.822 rs6815312 chr4:99058220 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 0.740 rs1382391 chr17:28111986 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT trans rs12785341 1.000 rs12294479 chr11:110395207 C/T cg05839347 chr2:3648246 COLEC11 0.43 6.74 0.52 5.25e-10 Renal sinus fat; TGCT cis rs909002 0.962 rs7537646 chr1:32135495 G/A cg11573219 chr1:32083031 HCRTR1 -0.42 -5.25 -0.43 6.29e-7 Intelligence (multi-trait analysis); TGCT cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg15659132 chr6:26577336 NA -0.57 -5.65 -0.45 1.05e-7 Intelligence (multi-trait analysis); TGCT cis rs7918232 0.941 rs1085782 chr10:27440517 G/A cg14442939 chr10:27389572 ANKRD26 -0.8 -5.32 -0.43 4.7e-7 Breast cancer; TGCT cis rs7546094 0.509 rs7415988 chr1:113159730 G/T cg10983938 chr1:113465962 AFARP1;SLC16A1 -0.21 -4.44 -0.37 1.99e-5 Platelet distribution width; TGCT cis rs939658 0.776 rs869672 chr15:79430860 G/A cg17916960 chr15:79447300 NA -0.49 -7.48 -0.56 1.21e-11 Refractive error; TGCT cis rs6938 0.534 rs1133322 chr15:75212357 A/G cg10253484 chr15:75165896 SCAMP2 -0.55 -5.08 -0.42 1.32e-6 Breast cancer; TGCT cis rs7805747 0.961 rs55779150 chr7:151406449 A/T cg17611936 chr7:151411526 PRKAG2 0.51 6.61 0.51 1e-9 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT trans rs9388451 0.626 rs9385383 chr6:126086290 G/T cg05039488 chr6:79577232 IRAK1BP1 -0.84 -10.02 -0.67 1.16e-17 Brugada syndrome; TGCT cis rs9303401 0.614 rs12947982 chr17:57140301 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.82 0.46 4.8e-8 Cognitive test performance; TGCT cis rs208520 0.955 rs9453664 chr6:66976079 A/C cg07460842 chr6:66804631 NA 0.77 6.83 0.52 3.34e-10 Exhaled nitric oxide output; TGCT cis rs499368 0.519 rs216247 chr12:310571 C/T cg23063825 chr12:298151 NA -0.38 -4.49 -0.37 1.62e-5 Blood metabolite levels;Metabolite levels; TGCT cis rs6815814 0.861 rs10034903 chr4:38784678 C/G cg02016764 chr4:38805732 TLR1 -0.28 -4.59 -0.38 1.06e-5 Breast cancer; TGCT cis rs7219021 0.770 rs7217007 chr17:46844697 C/T cg07967210 chr17:47022446 SNF8 0.39 4.78 0.39 4.96e-6 Schizophrenia or bipolar disorder; TGCT cis rs7020830 0.894 rs12337316 chr9:37148105 G/A cg14294708 chr9:37120828 ZCCHC7 1.18 16.96 0.84 4.1e-34 Schizophrenia; TGCT cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.855 rs6090205 chr20:61665269 A/G cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs9611565 0.512 rs132784 chr22:42052363 G/A cg13695892 chr22:41940480 POLR3H 0.86 7.84 0.58 1.77e-12 Vitiligo; TGCT cis rs3733585 0.673 rs4467564 chr4:9953472 G/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7587476 0.601 rs13021937 chr2:215673937 C/T cg04004882 chr2:215674386 BARD1 -0.65 -5.13 -0.42 1.09e-6 Neuroblastoma; TGCT cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs4242434 0.698 rs10104039 chr8:22538384 A/G cg03733263 chr8:22462867 KIAA1967 -1.04 -14.26 -0.79 6.7e-28 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7829975 0.593 rs2979241 chr8:8303353 G/C cg06636001 chr8:8085503 FLJ10661 0.69 6.31 0.49 4.44e-9 Mood instability; TGCT cis rs4819052 0.851 rs4819040 chr21:46659762 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.94 0.41 2.45e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9399137 0.507 rs13064 chr6:135287533 A/G cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs6933660 0.800 rs2046371 chr6:151754744 G/A cg17179660 chr6:151773299 C6orf211;RMND1 -0.55 -4.88 -0.4 3.16e-6 Menarche (age at onset); TGCT cis rs559928 0.548 rs11231713 chr11:63931849 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.56 0.38 1.22e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs1453308 1.000 rs4663225 chr2:237188566 C/T cg19324714 chr2:237145437 ASB18 0.59 5.21 0.42 7.8e-7 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs7647973 0.626 rs9824435 chr3:49674343 A/G cg05785598 chr3:49045655 WDR6 -0.42 -5.05 -0.41 1.53e-6 Menarche (age at onset); TGCT cis rs2692947 0.630 rs1168966 chr2:96798510 G/A cg22654517 chr2:96458247 NA 0.22 5.01 0.41 1.82e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9807989 0.839 rs10192036 chr2:102968211 C/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs79349575 0.777 rs28517720 chr17:46976756 C/G cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.04e-6 Type 2 diabetes; TGCT cis rs1218582 0.772 rs11264282 chr1:154867370 G/A cg06221963 chr1:154839813 KCNN3 -0.76 -13.04 -0.76 5.35e-25 Prostate cancer; TGCT cis rs3087591 0.960 rs2066736 chr17:29559932 C/A cg24425628 chr17:29625626 OMG;NF1 -0.46 -7.1 -0.54 8.41e-11 Hip circumference; TGCT cis rs6089829 0.962 rs6062780 chr20:61666648 T/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2278034 0.516 rs9829709 chr3:195616673 G/A cg16000393 chr3:195602323 TNK2 -0.16 -4.88 -0.4 3.21e-6 Bronchopulmonary dysplasia; TGCT cis rs8062405 0.964 rs62036614 chr16:28824685 T/C cg09754948 chr16:28834200 ATXN2L 0.6 4.51 0.38 1.5e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9296092 0.538 rs62405942 chr6:33517346 G/A cg13560919 chr6:33536144 NA -0.21 -4.74 -0.39 5.87e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs11673344 0.523 rs1402468 chr19:37620248 A/T cg08039142 chr19:36980659 ZNF566 0.52 4.83 0.4 3.89e-6 Obesity-related traits; TGCT cis rs218265 0.841 rs218263 chr4:55408104 C/T cg20208633 chr4:55405888 NA -0.55 -4.45 -0.37 1.92e-5 Sum neutrophil eosinophil counts;Myeloid white cell count;High light scatter reticulocyte percentage of red cells;Mean corpuscular volume;Reticulocyte fraction of red cells;Red blood cell count;Immature fraction of reticulocytes;Sum basophil neutrophil counts;Granulocyte count;White blood cell count;Neutrophil count;Mean corpuscular hemoglobin;Plateletcrit; TGCT cis rs208520 0.690 rs851465 chr6:66840293 G/A cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs9926296 0.509 rs2159113 chr16:89832083 C/T cg27121462 chr16:89883253 FANCA 0.53 4.87 0.4 3.33e-6 Vitiligo; TGCT cis rs12136530 0.593 rs11578302 chr1:19724835 A/G cg09329407 chr1:19054906 PAX7 -0.24 -4.5 -0.37 1.57e-5 Lead levels in blood; TGCT cis rs903263 0.932 rs6576962 chr1:84604937 C/T cg09664975 chr1:84543551 PRKACB 0.5 4.87 0.4 3.4e-6 Breast cancer (male); TGCT cis rs7226408 0.948 rs72883565 chr18:34380148 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.56 0.38 1.21e-5 Obesity-related traits; TGCT cis rs17125944 1.000 rs17125924 chr14:53391680 A/G cg00686598 chr14:53173677 PSMC6 0.92 4.54 0.38 1.29e-5 Alzheimer's disease (late onset); TGCT cis rs4851266 1.000 rs4851268 chr2:100825864 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs7937682 0.889 rs1784785 chr11:111483306 A/G cg09085632 chr11:111637200 PPP2R1B -1.05 -11.39 -0.72 5.21e-21 Primary sclerosing cholangitis; TGCT cis rs9467773 1.000 rs6903973 chr6:26499942 C/A cg26531700 chr6:26746687 NA 0.46 4.55 0.38 1.27e-5 Intelligence (multi-trait analysis); TGCT cis rs7937682 0.564 rs1944116 chr11:111366792 A/C cg09085632 chr11:111637200 PPP2R1B 0.55 4.94 0.41 2.52e-6 Primary sclerosing cholangitis; TGCT cis rs478304 0.654 rs10896035 chr11:65461160 G/A cg27068330 chr11:65405492 SIPA1 -0.99 -11.32 -0.71 7.67e-21 Acne (severe); TGCT cis rs7727544 0.547 rs10076758 chr5:131524299 A/G cg14196790 chr5:131705035 SLC22A5 0.33 4.49 0.37 1.59e-5 Blood metabolite levels; TGCT cis rs6714788 0.523 rs6542905 chr2:100654707 C/G cg22139774 chr2:100720529 AFF3 -0.41 -6.5 -0.5 1.74e-9 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs5001130 chr6:8442298 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs7666738 0.830 rs1527517 chr4:98931907 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 1.000 rs2012221 chr2:233566848 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.44 0.5 2.36e-9 Coronary artery disease; TGCT cis rs593982 0.920 rs72922791 chr11:65567395 G/A cg08755490 chr11:65554678 OVOL1 -1.06 -6.73 -0.52 5.74e-10 Atopic dermatitis; TGCT cis rs6424115 0.800 rs4649123 chr1:24197696 A/G cg15997130 chr1:24165203 NA 0.86 9.63 0.65 1.02e-16 Immature fraction of reticulocytes; TGCT cis rs472402 0.560 rs2303705 chr5:6622017 A/C cg06614609 chr5:6605060 NSUN2 0.17 4.47 0.37 1.76e-5 Response to amphetamines; TGCT cis rs28489187 0.617 rs233124 chr1:85791658 A/G cg16011679 chr1:85725395 C1orf52 0.49 4.49 0.37 1.63e-5 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs6671200 1.000 rs259346 chr1:95728746 G/T cg03123541 chr1:95699097 RWDD3 0.91 6.4 0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs9325144 0.505 rs7138977 chr12:38642109 G/A cg26384229 chr12:38710491 ALG10B 0.74 7.25 0.55 3.97e-11 Morning vs. evening chronotype; TGCT cis rs2075165 0.901 rs1043165 chr1:156220056 T/C cg20302342 chr1:156215951 PAQR6 0.39 5.64 0.45 1.12e-7 Tonsillectomy; TGCT cis rs6089584 0.507 rs6061990 chr20:60628429 T/G cg13770153 chr20:60521292 NA -0.43 -5.31 -0.43 4.99e-7 Body mass index; TGCT cis rs9811920 0.609 rs793465 chr3:99627750 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.82 -0.52 3.63e-10 Axial length; TGCT cis rs9322193 0.923 rs12174716 chr6:149965623 C/T cg13206674 chr6:150067644 NUP43 0.51 4.45 0.37 1.91e-5 Lung cancer; TGCT cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg19729930 chr2:74357872 NA 0.62 8.94 0.63 4.63e-15 Gestational age at birth (maternal effect); TGCT cis rs12477438 0.798 rs4622780 chr2:99631760 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.69 -5.87 -0.47 3.64e-8 Chronic sinus infection; TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg14820908 chr5:178986412 RUFY1 -0.54 -5.76 -0.46 6.26e-8 Lung cancer; TGCT cis rs9993613 0.875 rs34647859 chr4:73490197 C/T cg15102770 chr4:73434591 ADAMTS3 0.5 4.59 0.38 1.05e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs2120019 1.000 rs7167285 chr15:75368769 A/G cg11632617 chr15:75315747 PPCDC -0.34 -4.82 -0.4 4.18e-6 Blood trace element (Zn levels); TGCT cis rs928736 0.557 rs2834083 chr21:34436973 A/G cg10915739 chr21:34405733 NA 0.39 4.87 0.4 3.33e-6 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9303542 0.625 rs17703636 chr17:46566890 C/T cg25032089 chr17:46643351 HOXB3 -0.5 -5.2 -0.42 8.15e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7312933 0.592 rs1551210 chr12:42865874 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.51 4.9 0.4 2.99e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs12908161 1.000 rs35316992 chr15:85248133 A/G cg17173187 chr15:85201210 NMB 0.59 6.77 0.52 4.55e-10 Schizophrenia; TGCT cis rs2760061 0.598 rs590657 chr1:228117581 A/C cg02753203 chr1:228287806 NA -0.34 -6.57 -0.51 1.24e-9 Diastolic blood pressure; TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg25767906 chr1:53392781 SCP2 -0.53 -6.21 -0.49 7.34e-9 Monocyte count; TGCT cis rs826838 1.000 rs11183747 chr12:38822595 A/G cg26384229 chr12:38710491 ALG10B -1.02 -10.12 -0.67 6.58e-18 Heart rate; TGCT cis rs10464366 0.746 rs12670510 chr7:39142146 A/G cg18850127 chr7:39170497 POU6F2 0.27 5.7 0.46 8.11e-8 IgG glycosylation; TGCT cis rs801193 1.000 rs2707836 chr7:66160435 A/C cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs10504229 1.000 rs111915672 chr8:58191665 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.19 -0.42 8.4e-7 Developmental language disorder (linguistic errors); TGCT cis rs922182 0.538 rs16947599 chr15:64260944 C/T cg02919090 chr15:64263738 DAPK2 -0.28 -4.93 -0.41 2.54e-6 Blood protein levels; TGCT cis rs11190604 1.000 rs4919468 chr10:102288343 G/C cg16342193 chr10:102329863 NA -0.44 -5.56 -0.45 1.58e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs7833790 0.660 rs1451995 chr8:82746123 G/C cg17211192 chr8:82754475 SNX16 0.95 8.83 0.62 8.45e-15 Diastolic blood pressure; TGCT cis rs524281 0.861 rs6591208 chr11:65949689 A/C cg00563793 chr11:65837595 PACS1 0.57 4.97 0.41 2.13e-6 Electroencephalogram traits; TGCT cis rs9733 0.628 rs11807409 chr1:150683423 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs17300741 0.509 rs4930195 chr11:64310649 C/T cg08822897 chr11:64258103 NA -0.26 -4.46 -0.37 1.79e-5 Uric acid levels; TGCT cis rs7666738 0.830 rs13110410 chr4:98920018 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.51 0.56 1e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1505368 0.789 rs13419353 chr2:213271459 A/T cg20637307 chr2:213403960 ERBB4 -0.47 -4.51 -0.38 1.48e-5 Symmetrical dimethylarginine levels; TGCT cis rs9581857 0.579 rs9581843 chr13:27980507 T/G cg22138327 chr13:27999177 GTF3A 0.74 5.46 0.44 2.53e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2832191 0.791 rs2832178 chr21:30479858 T/G cg08807101 chr21:30365312 RNF160 -0.64 -6.01 -0.48 1.91e-8 Dental caries; TGCT cis rs7255045 0.711 rs2077544 chr19:12963285 C/T cg23899408 chr19:12877188 HOOK2 -0.56 -4.44 -0.37 1.96e-5 Mean corpuscular volume; TGCT cis rs1005224 0.853 rs12898082 chr14:76306359 A/C cg04684003 chr14:76127793 TTLL5;C14orf1 0.56 5.18 0.42 8.54e-7 Large artery stroke; TGCT cis rs931608 0.640 rs2957824 chr19:22579316 T/C cg08394602 chr19:22123885 NA 0.5 4.47 0.37 1.76e-5 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs7677751 0.806 rs6836215 chr4:55102741 T/C cg17187183 chr4:55093834 PDGFRA 0.54 7.0 0.53 1.45e-10 Corneal astigmatism; TGCT cis rs10114408 0.959 rs10992961 chr9:96653239 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT trans rs4332037 0.851 rs10268609 chr7:1962163 A/C cg25206134 chr2:45395956 NA 1.1 9.69 0.66 7.33e-17 Bipolar disorder; TGCT cis rs62244186 0.627 rs3935212 chr3:44460954 G/A cg17546649 chr3:44802566 KIF15;KIAA1143 -0.37 -4.49 -0.37 1.64e-5 Depressive symptoms; TGCT cis rs7940866 0.774 rs2162059 chr11:130831224 C/T cg05962950 chr11:130786565 SNX19 0.77 7.84 0.58 1.74e-12 Schizophrenia; TGCT cis rs151997 0.925 rs27287 chr5:50195567 C/A cg06027927 chr5:50259733 NA 0.48 4.95 0.41 2.41e-6 Callous-unemotional behaviour; TGCT cis rs2637266 0.935 rs7393727 chr10:78365977 T/A cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs7714584 1.000 rs11748151 chr5:150226292 C/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT trans rs10506458 1.000 rs12425655 chr12:63434463 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.44 -7.32 -0.55 2.74e-11 Hemostatic factors and hematological phenotypes; TGCT trans rs1496653 0.602 rs34504120 chr3:23369340 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1395 0.925 rs1659689 chr2:27393030 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.48 -6.02 -0.48 1.8e-8 Blood metabolite levels; TGCT cis rs7937682 0.924 rs499750 chr11:111513645 T/G cg09085632 chr11:111637200 PPP2R1B -1.09 -11.4 -0.72 4.97e-21 Primary sclerosing cholangitis; TGCT cis rs9611565 0.559 rs8139993 chr22:41995335 T/C cg13695892 chr22:41940480 POLR3H -0.83 -7.82 -0.57 1.94e-12 Vitiligo; TGCT cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.05 -9.12 -0.63 1.65e-15 Platelet count; TGCT cis rs1205863 0.607 rs1205850 chr6:11940593 C/G cg07106625 chr6:11870215 NA 0.44 4.77 0.39 5.18e-6 Disc degeneration (lumbar); TGCT cis rs3027009 0.881 rs12045546 chr1:159132532 A/G cg03685774 chr1:159870326 CCDC19 0.51 4.72 0.39 6.23e-6 Lean body mass and age at menarche (combined); TGCT cis rs3087591 0.960 rs2071009 chr17:29558082 T/C cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.33 -0.55 2.62e-11 Hip circumference; TGCT cis rs10392 0.500 rs8118646 chr20:37600887 A/G cg27552599 chr20:37590471 DHX35 0.37 4.62 0.38 9.29e-6 Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis; TGCT trans rs28735056 1.000 rs28865701 chr18:77620911 A/G cg05926928 chr17:57297772 GDPD1 -0.67 -7.05 -0.53 1.08e-10 Schizophrenia; TGCT cis rs7659604 0.540 rs67150579 chr4:122704331 T/A cg19748678 chr4:122722346 EXOSC9 -0.6 -5.85 -0.46 4.14e-8 Type 2 diabetes; TGCT cis rs9291683 0.546 rs10939672 chr4:10052136 A/G cg00071950 chr4:10020882 SLC2A9 0.54 5.95 0.47 2.56e-8 Bone mineral density; TGCT cis rs200810 0.964 rs28657486 chr6:97769261 T/C cg17774634 chr6:97730494 C6orf167;MIR548H3 -0.54 -4.69 -0.39 7.07e-6 Body mass index; TGCT cis rs8038465 0.874 rs11072434 chr15:74002854 A/G cg15420318 chr15:73925796 NPTN -0.56 -5.02 -0.41 1.73e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1552244 0.554 rs58020561 chr3:10054682 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs950169 0.881 rs4842852 chr15:84941961 A/G cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs11696501 0.694 rs6124722 chr20:44263264 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs9653442 0.622 rs11685341 chr2:100636757 A/G cg07810366 chr2:100720526 AFF3 0.38 6.09 0.48 1.28e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2239547 0.522 rs9842974 chr3:53011050 C/A cg10802521 chr3:52805072 NEK4 -0.59 -5.41 -0.44 3.08e-7 Schizophrenia; TGCT cis rs9611565 0.649 rs6002480 chr22:42176917 A/T cg06481639 chr22:41940642 POLR3H -0.52 -4.45 -0.37 1.9e-5 Vitiligo; TGCT cis rs78487399 0.808 rs79271345 chr2:43746094 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12142240 0.698 rs6696777 chr1:46810970 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs912057 0.601 rs1294413 chr6:6739924 C/A cg06612196 chr6:6737390 NA 0.5 7.47 0.56 1.24e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs8017423 0.647 rs1958345 chr14:90823770 T/C cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg04389838 chr3:44770851 ZNF501 -0.37 -4.76 -0.39 5.25e-6 Depressive symptoms; TGCT cis rs7647973 1.000 rs7648995 chr3:49438803 C/T cg05785598 chr3:49045655 WDR6 -0.4 -4.67 -0.39 7.57e-6 Menarche (age at onset); TGCT cis rs1949733 1.000 rs2688233 chr4:8491885 T/C cg11789530 chr4:8429930 ACOX3 0.6 5.49 0.44 2.21e-7 Response to antineoplastic agents; TGCT cis rs7267979 1.000 rs2856 chr20:25433536 T/C cg16686733 chr20:25566563 NINL 0.58 5.75 0.46 6.46e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2153535 0.580 rs9379206 chr6:8458021 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs12510870 0.599 rs1881611 chr4:74403462 G/A cg05868023 chr4:75230803 EREG 0.54 5.01 0.41 1.83e-6 Iris color (b* coordinate); TGCT cis rs700651 0.821 rs4850812 chr2:198743655 G/T cg00792783 chr2:198669748 PLCL1 -0.56 -5.08 -0.42 1.35e-6 Intracranial aneurysm; TGCT cis rs7296418 0.883 rs1727312 chr12:123642220 G/T cg00376283 chr12:123451042 ABCB9 0.84 7.66 0.57 4.68e-12 Platelet count; TGCT cis rs2033711 0.840 rs3764533 chr19:58929194 A/G cg12042659 chr19:58951599 ZNF132 0.51 4.6 0.38 1.05e-5 Uric acid clearance; TGCT cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg03452623 chr4:187889614 NA -0.32 -4.84 -0.4 3.77e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7027203 0.828 rs10122041 chr9:96615517 A/G cg14396892 chr9:96623032 NA -0.26 -5.46 -0.44 2.51e-7 DNA methylation (variation); TGCT cis rs3796352 1.000 rs11714876 chr3:53101640 C/G cg27565382 chr3:53032988 SFMBT1 -0.44 -4.74 -0.39 5.86e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9858542 0.953 rs11922013 chr3:49458355 G/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg15687855 chr3:44754131 ZNF502 -0.55 -6.8 -0.52 3.89e-10 Depressive symptoms; TGCT cis rs9467773 0.967 rs7753565 chr6:26560012 A/G cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs6088580 0.542 rs6059882 chr20:33090167 T/C cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs4319547 0.794 rs61954972 chr12:123074167 T/G cg23029597 chr12:123009494 RSRC2 -0.3 -4.92 -0.4 2.65e-6 Body mass index; TGCT cis rs9911578 1.000 rs8079774 chr17:56908188 A/G cg12560992 chr17:57184187 TRIM37 0.75 9.07 0.63 2.26e-15 Intelligence (multi-trait analysis); TGCT cis rs2075371 0.897 rs12667905 chr7:134000812 A/C cg11752832 chr7:134001865 SLC35B4 0.67 5.91 0.47 3.12e-8 Mean platelet volume; TGCT cis rs28595532 0.920 rs17324807 chr4:119770638 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9787249 0.957 rs12239844 chr1:40217258 T/C cg24920358 chr1:40204285 PPIE 0.58 10.56 0.69 5.56e-19 Blood protein levels; TGCT cis rs752092 0.802 rs2412005 chr15:101767591 T/A cg25114630 chr15:101792522 CHSY1 0.5 4.73 0.39 6.12e-6 Corneal structure; TGCT cis rs6121246 0.909 rs6119729 chr20:30413163 A/G cg18721089 chr20:30220636 NA 0.43 4.75 0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs35883536 0.647 rs12026951 chr1:101046273 C/T cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs6912958 1.000 rs6937823 chr6:88160386 G/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.39 -5.0 -0.41 1.91e-6 Monocyte percentage of white cells; TGCT cis rs988712 0.672 rs35038967 chr11:27703480 T/A cg10635145 chr11:27742435 BDNF -0.43 -5.98 -0.47 2.19e-8 Obesity; TGCT cis rs11722228 1.000 rs4697695 chr4:9915850 C/T cg11266682 chr4:10021025 SLC2A9 0.52 5.57 0.45 1.53e-7 Gout;Urate levels;Serum uric acid levels; TGCT cis rs6964587 0.692 rs6970629 chr7:91846599 T/C cg17063962 chr7:91808500 NA 0.77 7.17 0.54 6.08e-11 Breast cancer; TGCT cis rs7772486 0.536 rs9373467 chr6:145955605 C/T cg13319975 chr6:146136371 FBXO30 -0.7 -6.39 -0.5 3.04e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg04234412 chr22:24373322 LOC391322 -0.93 -11.15 -0.71 1.99e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11190604 0.945 rs11190573 chr10:102233172 T/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1372520 0.873 rs2583990 chr4:90771499 A/G cg01966878 chr4:90757139 SNCA -0.31 -5.0 -0.41 1.9e-6 Neuroticism; TGCT cis rs36051895 0.659 rs4495487 chr9:5072798 T/C cg02405213 chr9:5042618 JAK2 -0.76 -9.95 -0.67 1.69e-17 Pediatric autoimmune diseases; TGCT cis rs7091068 0.518 rs9633674 chr10:95455431 C/T cg20715218 chr10:95462985 C10orf4 0.52 5.5 0.44 2.07e-7 Urinary tract infection frequency; TGCT cis rs1887596 0.639 rs9553873 chr13:27186843 T/C cg01312412 chr13:27282625 NA 0.3 5.46 0.44 2.45e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs2836633 0.929 rs4514962 chr21:40041753 C/T cg05519781 chr21:40033154 ERG 0.69 6.82 0.52 3.63e-10 Coronary artery disease; TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg25151919 chr3:44754333 ZNF502 -0.43 -5.02 -0.41 1.75e-6 Depressive symptoms; TGCT cis rs875971 0.825 rs7384021 chr7:66077904 A/G cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.89e-6 Aortic root size; TGCT cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg03517284 chr6:25882590 NA -0.58 -6.02 -0.48 1.79e-8 Blood metabolite levels; TGCT cis rs6484504 0.553 rs2183484 chr11:31259370 G/A cg26647111 chr11:31128758 NA -0.35 -4.85 -0.4 3.58e-6 Red blood cell count; TGCT cis rs9611565 0.592 rs5996037 chr22:41965292 A/G cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs617219 0.671 rs13165414 chr5:78548873 C/T cg23514016 chr5:78407564 BHMT 0.32 4.87 0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9291683 0.527 rs11727087 chr4:10096020 A/G cg11266682 chr4:10021025 SLC2A9 0.57 6.74 0.52 5.32e-10 Bone mineral density; TGCT cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg08280861 chr8:58055591 NA 0.51 5.73 0.46 7.17e-8 Developmental language disorder (linguistic errors); TGCT cis rs3818285 0.655 rs2475277 chr10:111639730 C/T cg00817464 chr10:111662876 XPNPEP1 0.32 5.56 0.45 1.57e-7 Superior crus of antihelix expression; TGCT cis rs79387448 0.745 rs1523197 chr2:103163732 A/G cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.07 0.41 1.38e-6 Vitiligo; TGCT cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs8072100 0.748 rs9908016 chr17:45551361 G/A cg08085267 chr17:45401833 C17orf57 -0.48 -5.23 -0.43 6.87e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs12210905 0.688 rs12195783 chr6:27444345 A/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs35146811 0.731 rs2257213 chr7:99810113 T/C cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs1580019 0.523 rs9791770 chr7:32582252 C/A cg06627557 chr7:32535165 LSM5;AVL9 1.2 15.12 0.81 6.42e-30 Cognitive ability; TGCT cis rs854765 0.583 rs8065563 chr17:17782404 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.92 0.58 1.17e-12 Total body bone mineral density; TGCT cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg02725872 chr8:58115012 NA -0.41 -4.95 -0.41 2.37e-6 Developmental language disorder (linguistic errors); TGCT cis rs881375 0.967 rs1860824 chr9:123659339 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.47 5.2 0.42 8.09e-7 Rheumatoid arthritis; TGCT cis rs77741769 0.571 rs4454799 chr12:121317075 A/C cg02419362 chr12:121203948 SPPL3 -0.19 -4.49 -0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs3771570 1.000 rs62186400 chr2:242226700 A/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs7020830 0.931 rs3802422 chr9:37097172 G/A cg14294708 chr9:37120828 ZCCHC7 1.28 20.28 0.88 3.46e-41 Schizophrenia; TGCT cis rs11718455 0.960 rs4682713 chr3:44013191 G/C cg08738300 chr3:44038990 NA 0.87 6.63 0.51 9.07e-10 Coronary artery disease; TGCT cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs981844 0.712 rs4469056 chr4:154745796 A/T cg14289246 chr4:154710475 SFRP2 0.99 9.12 0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs4819052 0.851 rs7275468 chr21:46656499 C/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.6 5.07 0.41 1.39e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11190604 1.000 rs3793771 chr10:102222957 C/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7647973 1.000 rs3870339 chr3:49536863 T/A cg05785598 chr3:49045655 WDR6 0.37 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs6987853 0.933 rs2974340 chr8:42397731 T/C cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs1865760 0.508 rs9379820 chr6:26049924 T/C cg17042849 chr6:26104293 HIST1H4C -0.62 -5.41 -0.44 3.18e-7 Height; TGCT cis rs11098499 0.738 rs28687057 chr4:120280812 A/G cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs9650657 0.740 rs2277130 chr8:10677601 G/C cg27411982 chr8:10470053 RP1L1 -0.23 -5.12 -0.42 1.13e-6 Neuroticism; TGCT cis rs7662987 0.517 rs2034696 chr4:100024322 C/G cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.86 -8.79 -0.62 1.01e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs12479064 0.671 rs62155807 chr2:100076579 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -6.02 -0.48 1.85e-8 Chronic sinus infection; TGCT cis rs4711350 0.862 rs652049 chr6:33711420 C/T cg18005901 chr6:33739558 LEMD2 0.57 5.9 0.47 3.23e-8 Schizophrenia; TGCT cis rs4820539 0.966 rs2267005 chr22:23461723 A/G cg21100191 chr22:23484243 RTDR1 0.9 11.01 0.7 4.35e-20 Bone mineral density; TGCT cis rs7191439 0.518 rs4238679 chr16:88742688 G/C cg27087555 chr16:88793112 FAM38A -0.47 -4.75 -0.39 5.46e-6 Plateletcrit; TGCT cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg06675483 chr6:26987649 LOC100270746;C6orf41 0.36 4.65 0.39 8.51e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2075371 0.796 rs10954440 chr7:134005657 C/T cg11752832 chr7:134001865 SLC35B4 0.71 6.37 0.5 3.39e-9 Mean platelet volume; TGCT cis rs6582630 0.599 rs7967598 chr12:38540760 C/T cg26384229 chr12:38710491 ALG10B -0.53 -4.77 -0.39 5.06e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs62209 0.752 rs1928720 chr10:11014351 T/A cg26901096 chr10:10994189 LOC254312 0.43 6.99 0.53 1.46e-10 Alzheimer's disease (late onset); TGCT cis rs8014204 0.935 rs4903267 chr14:75360419 G/T cg06637938 chr14:75390232 RPS6KL1 -0.75 -7.22 -0.54 4.62e-11 Caffeine consumption; TGCT cis rs13091206 1 rs13091206 chr3:49238718 A/G cg07636037 chr3:49044803 WDR6 0.83 6.33 0.49 4.16e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1348850 0.750 rs12997716 chr2:178494629 G/A cg22681709 chr2:178499509 PDE11A -0.47 -5.62 -0.45 1.18e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs11190604 0.767 rs10786590 chr10:102164604 T/C cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12681288 0.676 rs17740799 chr8:1014327 C/T cg08872321 chr8:1308229 NA 0.24 4.44 0.37 1.94e-5 Schizophrenia; TGCT cis rs6666258 1.000 rs6666258 chr1:154814268 G/C cg06418219 chr1:154948305 SHC1;CKS1B 0.62 5.04 0.41 1.59e-6 Atrial fibrillation; TGCT cis rs7267979 0.753 rs400357 chr20:25479058 A/G cg03522245 chr20:25566470 NINL 0.55 5.55 0.45 1.69e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62244186 0.659 rs9855433 chr3:44468065 C/A cg10108389 chr3:44770937 ZNF501 -0.47 -4.76 -0.39 5.34e-6 Depressive symptoms; TGCT cis rs4919694 1.000 rs4919694 chr10:104698978 T/C cg04362960 chr10:104952993 NT5C2 1.02 6.9 0.53 2.41e-10 Arsenic metabolism; TGCT cis rs2862064 1.000 rs1910052 chr5:156429154 T/C cg12943317 chr5:156479607 HAVCR1 -0.45 -5.92 -0.47 2.96e-8 Platelet count; TGCT cis rs968451 0.762 rs5757618 chr22:39724551 A/T cg17798944 chr22:39715225 SNORD43;RPL3 0.85 8.61 0.61 2.85e-14 Primary biliary cholangitis; TGCT cis rs4788570 0.615 rs10852503 chr16:71652227 G/C cg06353428 chr16:71660113 MARVELD3 1.55 12.96 0.76 8.29e-25 Intelligence (multi-trait analysis); TGCT cis rs12220238 1.000 rs10824088 chr10:75921490 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9911578 1.000 rs8079774 chr17:56908188 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.06 -0.48 1.53e-8 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg23131131 chr22:24373011 LOC391322 -0.66 -6.75 -0.52 5.03e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6750047 0.566 rs1157184 chr2:38285774 C/G cg07380506 chr2:38303506 CYP1B1 0.68 6.34 0.49 3.98e-9 Cutaneous malignant melanoma;Melanoma; TGCT cis rs12220898 0.749 rs10857456 chr10:50474756 A/G cg06072769 chr10:50146962 WDFY4 0.36 4.67 0.39 7.64e-6 Inflammatory biomarkers; TGCT cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg20607798 chr8:58055168 NA 0.45 4.62 0.38 9.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs2072499 0.750 rs55675376 chr1:156165881 C/T cg24450063 chr1:156163899 SLC25A44 1.13 10.64 0.69 3.48e-19 Testicular germ cell tumor; TGCT cis rs7959452 0.535 rs1350166 chr12:69636314 G/T cg14784868 chr12:69753453 YEATS4 0.69 7.0 0.53 1.39e-10 Blood protein levels; TGCT cis rs11098499 0.909 rs2127821 chr4:120394535 T/C cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs8017423 0.967 rs11627429 chr14:90689232 G/A cg04374321 chr14:90722782 PSMC1 -0.76 -7.83 -0.58 1.9e-12 Mortality in heart failure; TGCT cis rs3796352 1.000 rs13069006 chr3:52973305 G/C cg07884673 chr3:53033167 SFMBT1 0.63 5.74 0.46 6.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg24675658 chr1:53192096 ZYG11B 0.89 11.91 0.73 2.9e-22 Monocyte count; TGCT cis rs2115630 0.902 rs8023276 chr15:85219638 C/T cg12501888 chr15:85177176 SCAND2 -0.49 -4.77 -0.39 5.18e-6 P wave terminal force; TGCT cis rs7714584 0.793 rs2161363 chr5:150182079 G/C cg22134413 chr5:150180641 NA 1.17 8.69 0.62 1.76e-14 Crohn's disease; TGCT cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4919669 0.623 rs2298278 chr10:104390303 A/G cg05855489 chr10:104503620 C10orf26 0.73 4.67 0.39 7.6e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs9653442 0.511 rs6739695 chr2:100859622 A/G cg22139774 chr2:100720529 AFF3 -0.38 -6.19 -0.49 8.08e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1163251 0.902 rs640195 chr1:120217650 T/A cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs939658 1.000 rs8031019 chr15:79458512 C/T cg17916960 chr15:79447300 NA -0.53 -8.43 -0.6 7.39e-14 Refractive error; TGCT cis rs13064411 0.696 rs2129434 chr3:113138763 A/C cg10517650 chr3:113235015 CCDC52 -0.35 -4.82 -0.4 4.2e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9868809 0.881 rs13096357 chr3:48675856 C/A cg00383909 chr3:49044727 WDR6 0.93 4.92 0.4 2.68e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs922182 0.663 rs55929105 chr15:64265804 C/T cg02919090 chr15:64263738 DAPK2 0.38 7.06 0.54 1.03e-10 Blood protein levels; TGCT cis rs791888 0.929 rs2755431 chr10:89415104 C/T cg13926569 chr10:89418898 PAPSS2 -0.35 -4.74 -0.39 5.67e-6 Magnesium levels; TGCT cis rs7829975 0.582 rs6983150 chr8:8792426 A/G cg06636001 chr8:8085503 FLJ10661 -0.72 -6.69 -0.52 6.68e-10 Mood instability; TGCT cis rs981844 0.816 rs62325145 chr4:154725687 G/C cg14289246 chr4:154710475 SFRP2 1.03 9.03 0.63 2.72e-15 Response to statins (LDL cholesterol change); TGCT cis rs7542091 0.704 rs12022221 chr1:210046178 A/C cg23283495 chr1:209979779 IRF6 0.52 5.25 0.43 6.36e-7 Monobrow; TGCT cis rs514406 0.861 rs551435 chr1:53260537 G/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs2120019 0.938 rs8028632 chr15:75321262 T/C cg17294928 chr15:75287854 SCAMP5 -0.79 -6.27 -0.49 5.46e-9 Blood trace element (Zn levels); TGCT cis rs7772486 0.686 rs857880 chr6:145971115 T/C cg13319975 chr6:146136371 FBXO30 0.54 4.98 0.41 2.09e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs763121 0.853 rs2267395 chr22:39113903 C/T cg06022373 chr22:39101656 GTPBP1 0.74 7.33 0.55 2.53e-11 Menopause (age at onset); TGCT cis rs7226408 0.857 rs72885273 chr18:34438538 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7647973 0.592 rs6774202 chr3:49687779 T/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs7772486 0.774 rs6930181 chr6:146180974 A/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.5 -0.37 1.53e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2657888 1.000 rs17540509 chr12:56943840 T/C cg23932658 chr12:57637574 STAC3 -0.52 -4.74 -0.39 5.78e-6 Adiponectin levels; TGCT cis rs9611565 0.559 rs132761 chr22:42004371 C/T cg17554472 chr22:41940697 POLR3H 0.5 5.35 0.43 4.07e-7 Vitiligo; TGCT cis rs4372836 0.576 rs6547880 chr2:29018889 T/C cg09522027 chr2:28974177 PPP1CB -0.69 -7.27 -0.55 3.54e-11 Body mass index; TGCT cis rs12497850 0.897 rs9850134 chr3:48957147 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs13256369 0.950 rs13255655 chr8:8577736 C/T cg18904891 chr8:8559673 CLDN23 0.62 5.39 0.44 3.41e-7 Obesity-related traits; TGCT cis rs72781680 0.756 rs2551337 chr2:24006886 C/T cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs933688 0.938 rs1477348 chr5:90707823 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.06 0.59 5.53e-13 Smoking behavior; TGCT cis rs4499344 0.693 rs8106502 chr19:33097796 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.7 0.62 1.68e-14 Mean platelet volume; TGCT cis rs59107033 0.607 rs9851257 chr3:123125711 T/A cg04890266 chr3:123102914 ADCY5 -0.37 -5.78 -0.46 5.69e-8 Lymphocyte counts; TGCT cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg08280861 chr8:58055591 NA 0.49 5.47 0.44 2.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4727027 0.727 rs1568944 chr7:148873497 A/T cg23583168 chr7:148888333 NA -0.68 -8.19 -0.59 2.74e-13 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs11673344 0.523 rs8101392 chr19:37515318 A/G cg08039142 chr19:36980659 ZNF566 0.5 4.72 0.39 6.26e-6 Obesity-related traits; TGCT trans rs2760061 0.819 rs708114 chr1:228197496 G/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.08 -0.54 9.57e-11 Diastolic blood pressure; TGCT cis rs514406 0.825 rs6588441 chr1:53223494 G/A cg16325326 chr1:53192061 ZYG11B -0.71 -8.82 -0.62 8.9e-15 Monocyte count; TGCT cis rs644799 0.965 rs687529 chr11:95545587 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9399135 1.000 rs11754265 chr6:135356216 C/G cg24558204 chr6:135376177 HBS1L 0.46 4.59 0.38 1.09e-5 Red blood cell count; TGCT cis rs9911578 1.000 rs302854 chr17:56683612 G/A cg05425664 chr17:57184151 TRIM37 -0.63 -6.24 -0.49 6.44e-9 Intelligence (multi-trait analysis); TGCT cis rs10056811 0.538 rs2035191 chr5:74413713 T/C cg00601450 chr5:74908170 NA 0.46 4.5 0.37 1.57e-5 Coronary artery disease; TGCT trans rs9354352 0.935 rs7766730 chr6:66697003 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.72 7.89 0.58 1.33e-12 Initial pursuit acceleration in psychotic disorders; TGCT cis rs981844 0.712 rs1037654 chr4:154750300 C/G cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs2180341 0.960 rs6913424 chr6:127707010 A/C cg27446573 chr6:127587934 RNF146 1.1 10.08 0.67 8.12e-18 Breast cancer; TGCT cis rs1949733 0.701 rs2631754 chr4:8449233 A/G cg11789530 chr4:8429930 ACOX3 0.53 4.99 0.41 2e-6 Response to antineoplastic agents; TGCT cis rs4727027 0.866 rs2373438 chr7:148780287 C/A cg23583168 chr7:148888333 NA -0.69 -8.76 -0.62 1.23e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12701220 0.817 rs7798459 chr7:1087965 C/T cg27454412 chr7:1067447 C7orf50 -0.48 -4.45 -0.37 1.87e-5 Bronchopulmonary dysplasia; TGCT cis rs79387448 0.745 rs7575867 chr2:103120179 C/T cg09003973 chr2:102972529 NA 0.85 5.65 0.45 1.03e-7 Gut microbiota (bacterial taxa); TGCT cis rs12188164 0.930 rs11743825 chr5:475463 C/T cg26850624 chr5:429559 AHRR -0.2 -4.85 -0.4 3.59e-6 Cystic fibrosis severity; TGCT cis rs1552244 0.882 rs56332224 chr3:10037321 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.43 -0.5 2.53e-9 Alzheimer's disease; TGCT cis rs7809950 0.678 rs62483641 chr7:106901741 T/C cg23024343 chr7:107201750 COG5 -0.43 -5.81 -0.46 4.86e-8 Coronary artery disease; TGCT cis rs7119 0.717 rs12901732 chr15:77818933 G/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.61 -0.38 9.81e-6 Type 2 diabetes; TGCT cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.57e-9 Type 2 diabetes; TGCT cis rs3902035 0.964 rs62423994 chr6:119011597 G/A cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs586688 0.625 rs481966 chr1:201655746 A/G cg14168733 chr1:201708718 NAV1 -0.55 -4.44 -0.37 1.93e-5 Obesity-related traits; TGCT cis rs17076896 0.708 rs61956079 chr13:19932611 A/G cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs4819052 0.851 rs2838832 chr21:46664904 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.73 -7.05 -0.54 1.09e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs977747 0.872 rs6658125 chr1:47677015 C/T cg03885399 chr1:47691550 TAL1 -0.42 -5.48 -0.44 2.27e-7 Body mass index; TGCT cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs41271951 0.542 rs12138787 chr1:150246070 T/C cg18798344 chr1:149336151 NA 0.56 4.5 0.37 1.52e-5 Blood protein levels; TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs3087591 0.683 rs757375 chr17:29717879 C/G cg24425628 chr17:29625626 OMG;NF1 0.4 5.87 0.47 3.67e-8 Hip circumference; TGCT trans rs561341 1.000 rs56903735 chr17:30254393 T/A cg20587970 chr11:113659929 NA -1.03 -11.15 -0.71 2.03e-20 Hip circumference adjusted for BMI; TGCT cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs713587 0.967 rs6752378 chr2:25150116 C/A cg15423357 chr2:25149977 NA 0.63 6.47 0.5 2.01e-9 Body mass index in non-asthmatics; TGCT cis rs10751667 0.643 rs7394436 chr11:970373 G/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs933688 0.938 rs7705465 chr5:90680949 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.15 0.59 3.39e-13 Smoking behavior; TGCT cis rs8068544 0.606 rs77681389 chr17:40154419 T/C cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.07 -5.1 -0.42 1.26e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs7694889 chr4:98855596 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9549367 0.789 rs34989271 chr13:113894766 G/A cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs7119 0.667 rs907392 chr15:77903393 T/C cg27398640 chr15:77910606 LINGO1 0.32 6.76 0.52 4.86e-10 Type 2 diabetes; TGCT cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg08280861 chr8:58055591 NA 0.39 4.76 0.39 5.35e-6 Developmental language disorder (linguistic errors); TGCT cis rs60843830 1.000 rs4497901 chr2:239969 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.75 7.58 0.56 6.94e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2832191 0.632 rs2246777 chr21:30309586 T/C cg24692254 chr21:30365293 RNF160 -0.94 -10.37 -0.68 1.6e-18 Dental caries; TGCT cis rs801193 0.935 rs2659916 chr7:66151352 C/G cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs6138458 1.000 rs227627 chr20:24912107 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg15242686 chr22:24348715 GSTTP1 0.42 5.66 0.45 1.01e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1008375 0.897 rs3733577 chr4:17649233 T/G cg16339924 chr4:17578868 LAP3 0.67 5.48 0.44 2.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7729723 0.533 rs219277 chr5:137833766 C/T cg19169342 chr5:137827400 NA 0.33 4.53 0.38 1.37e-5 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs7582180 0.629 rs13031508 chr2:100952757 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.82 -0.4 4.16e-6 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.710 rs2469541 chr15:76562118 C/T cg22467129 chr15:76604101 ETFA 0.69 8.66 0.61 2.1e-14 Blood metabolite levels; TGCT cis rs12579753 0.917 rs12372724 chr12:82193628 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs231513 0.911 rs231515 chr17:41964083 A/G cg26893861 chr17:41843967 DUSP3 -0.71 -5.21 -0.42 7.57e-7 Cognitive function; TGCT cis rs1371867 0.875 rs1660344 chr8:101324659 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs939658 0.683 rs8038464 chr15:79463036 A/T cg17916960 chr15:79447300 NA -0.42 -6.64 -0.51 8.59e-10 Refractive error; TGCT trans rs208520 0.661 rs7747492 chr6:66857788 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs804280 0.662 rs11784693 chr8:11610674 C/T cg26752888 chr8:11627280 NEIL2 0.69 5.48 0.44 2.32e-7 Myopia (pathological); TGCT cis rs11249608 0.636 rs6868893 chr5:178449826 C/A cg01312482 chr5:178451176 ZNF879 -0.57 -5.6 -0.45 1.34e-7 Pubertal anthropometrics; TGCT cis rs4273100 0.688 rs12939947 chr17:19204531 A/T cg03910582 chr17:19030146 GRAPL 0.53 6.46 0.5 2.11e-9 Schizophrenia; TGCT cis rs7523050 0.643 rs36047249 chr1:109401499 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs3091242 0.933 rs3093584 chr1:25668714 T/C cg23205692 chr1:25664452 TMEM50A -0.51 -5.22 -0.42 7.26e-7 Erythrocyte sedimentation rate; TGCT cis rs3087591 0.708 rs3815154 chr17:29654974 G/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.46 0.44 2.45e-7 Hip circumference; TGCT cis rs12693043 0.727 rs6748959 chr2:175424127 C/T cg11778734 chr2:175439522 WIPF1 -0.37 -4.82 -0.4 4.09e-6 Urate levels (BMI interaction); TGCT cis rs6840360 0.642 rs7658169 chr4:152353414 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs694739 0.892 rs647152 chr11:64109118 T/G cg02228329 chr11:64053129 BAD;GPR137 0.72 7.0 0.53 1.43e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs6912958 0.703 rs6903219 chr6:88096498 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.62 6.12 0.48 1.13e-8 Monocyte percentage of white cells; TGCT cis rs17331151 0.573 rs4687556 chr3:52890475 T/C cg15956490 chr3:53032818 SFMBT1 -0.47 -5.9 -0.47 3.27e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3858526 0.883 rs7481882 chr11:5944221 A/G cg05234568 chr11:5960015 NA -0.46 -4.51 -0.38 1.45e-5 DNA methylation (variation); TGCT cis rs4144743 1.000 rs4144743 chr17:45323125 A/G cg18085866 chr17:45331354 ITGB3 -0.72 -4.88 -0.4 3.15e-6 Body mass index; TGCT cis rs12549902 0.933 rs17659428 chr8:41513809 T/C cg21772509 chr8:41503840 NKX6-3 0.85 9.62 0.65 1.04e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs5769707 0.605 rs9616702 chr22:50025938 A/G cg06623630 chr22:50017776 C22orf34 -0.27 -4.65 -0.39 8.38e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6582630 0.599 rs12309369 chr12:38419683 C/G cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12477438 0.520 rs13010904 chr2:99754289 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.85 8.37 0.6 1.02e-13 Chronic sinus infection; TGCT cis rs2239547 0.657 rs4687554 chr3:52864135 T/C cg11645453 chr3:52864694 ITIH4 0.34 5.69 0.46 8.61e-8 Schizophrenia; TGCT cis rs11648796 0.718 rs62032512 chr16:764826 C/T cg07343612 chr16:622815 PIGQ -0.36 -5.0 -0.41 1.89e-6 Height; TGCT cis rs910187 0.605 rs3787239 chr20:45802729 T/C cg27589058 chr20:45804311 EYA2 -0.4 -8.74 -0.62 1.37e-14 Migraine; TGCT cis rs62380364 0.602 rs589544 chr5:88064462 T/C cg24804195 chr5:87968844 LOC645323 -0.55 -5.34 -0.43 4.23e-7 Intelligence (multi-trait analysis); TGCT cis rs892961 0.720 rs103458 chr17:75416031 A/G cg05865280 chr17:75406074 SEPT9 0.29 6.83 0.52 3.46e-10 Airflow obstruction; TGCT cis rs6089584 0.854 rs6061985 chr20:60622362 T/C cg13770153 chr20:60521292 NA -0.54 -7.12 -0.54 7.73e-11 Body mass index; TGCT cis rs2562456 0.833 rs2681388 chr19:21732253 G/C cg01304269 chr19:21688519 ZNF429 0.57 4.74 0.39 5.86e-6 Pain; TGCT cis rs12210905 1.000 rs12205921 chr6:27113540 G/T cg08851530 chr6:28072375 NA 1.05 5.16 0.42 9.42e-7 Hip circumference adjusted for BMI; TGCT cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg05785598 chr3:49045655 WDR6 0.38 5.12 0.42 1.14e-6 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7568458 0.709 rs1446669 chr2:85762209 T/C cg17127132 chr2:85788382 GGCX 0.52 4.77 0.39 5.12e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs12549902 0.966 rs6990613 chr8:41515130 A/G cg21772509 chr8:41503840 NKX6-3 0.86 9.58 0.65 1.35e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs514406 0.861 rs1571979 chr1:53237526 G/A cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs763121 0.925 rs4821797 chr22:39016182 T/C cg06022373 chr22:39101656 GTPBP1 0.79 7.98 0.58 8.44e-13 Menopause (age at onset); TGCT cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs8017423 0.935 rs7158410 chr14:90704370 T/C cg04374321 chr14:90722782 PSMC1 0.77 8.04 0.59 6.19e-13 Mortality in heart failure; TGCT cis rs6669919 0.967 rs7513031 chr1:211671900 C/T cg26515805 chr1:211431828 RCOR3 0.4 4.66 0.39 7.93e-6 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs4405313 chr11:50013636 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg10263370 chr3:44754102 ZNF502 -0.44 -5.26 -0.43 6.2e-7 Depressive symptoms; TGCT cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg08048268 chr3:133502702 NA -0.67 -10.27 -0.68 2.75e-18 Iron status biomarkers; TGCT cis rs9549367 0.713 rs9549356 chr13:113851633 A/G cg00898013 chr13:113819073 PROZ -0.53 -6.94 -0.53 1.89e-10 Platelet distribution width; TGCT cis rs9486719 1.000 rs2179126 chr6:96871350 A/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs9308731 0.583 rs10211562 chr2:111930796 G/T cg04202892 chr2:111875749 ACOXL 0.45 5.11 0.42 1.21e-6 Chronic lymphocytic leukemia; TGCT cis rs7953249 0.656 rs6489786 chr12:121397875 A/G cg02403541 chr12:121454288 C12orf43 -0.62 -5.3 -0.43 5.11e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs1215050 0.755 rs811479 chr4:98727398 A/T cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4727027 0.870 rs1534196 chr7:148790591 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.9 0.4 2.96e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs977747 0.815 rs11211480 chr1:47693220 A/G cg03885399 chr1:47691550 TAL1 -0.39 -5.12 -0.42 1.11e-6 Body mass index; TGCT cis rs1903068 0.853 rs12331471 chr4:56001509 T/C cg16572876 chr4:56024045 NA 0.43 4.94 0.41 2.43e-6 Endometriosis; TGCT cis rs9814567 1.000 rs9851441 chr3:134315091 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.78 -0.62 1.1e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs950169 1.000 rs62026530 chr15:84775840 G/T cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.07e-8 Schizophrenia; TGCT cis rs155076 0.711 rs9550724 chr13:21885030 G/T cg14456004 chr13:21872349 NA 1.25 12.41 0.74 1.76e-23 White matter hyperintensity burden; TGCT cis rs4746818 1.000 rs4746818 chr10:70884687 G/T cg11621586 chr10:70884670 VPS26A 1.19 11.41 0.72 4.59e-21 Left atrial antero-posterior diameter; TGCT cis rs2463822 0.920 rs11828383 chr11:62067818 C/T cg06239285 chr11:62104954 ASRGL1 -0.89 -5.48 -0.44 2.32e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs473651 0.837 rs563458 chr2:239345613 T/A cg08773314 chr2:239334832 ASB1 0.45 7.45 0.56 1.38e-11 Multiple system atrophy; TGCT cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs270601 0.710 rs371709 chr5:131583240 A/G cg12564285 chr5:131593104 PDLIM4 0.38 4.64 0.38 8.61e-6 Acylcarnitine levels; TGCT cis rs2153535 0.580 rs9406164 chr6:8470048 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs6543140 0.964 rs10169192 chr2:103072211 A/G cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs1865760 0.566 rs2032445 chr6:26044812 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.31 0.55 2.87e-11 Height; TGCT cis rs4711350 0.862 rs530614 chr6:33714781 G/A cg00334056 chr6:33755658 LEMD2 0.31 4.77 0.39 5.04e-6 Schizophrenia; TGCT cis rs11627546 0.615 rs61980616 chr14:70366459 C/T cg10496350 chr14:71275911 MAP3K9 -0.94 -4.44 -0.37 1.96e-5 Red blood cell traits; TGCT cis rs67311347 0.544 rs6762121 chr3:40355313 G/A cg13683864 chr3:40499215 RPL14 -0.84 -7.85 -0.58 1.71e-12 Renal cell carcinoma; TGCT cis rs2404602 1.000 rs2120107 chr15:76869789 A/G cg26408565 chr15:76604113 ETFA -0.35 -4.56 -0.38 1.22e-5 Blood metabolite levels; TGCT cis rs2041840 0.960 rs2058716 chr2:37510013 C/G cg22629987 chr2:37571677 QPCT 0.46 4.5 0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg09222892 chr1:25734099 RHCE -0.44 -7.02 -0.53 1.3100000000000001e-10 Erythrocyte sedimentation rate; TGCT cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.44 -0.6 6.87e-14 Platelet count; TGCT cis rs7100689 0.784 rs10736342 chr10:82130005 A/G cg01528321 chr10:82214614 TSPAN14 0.88 8.48 0.61 5.61e-14 Post bronchodilator FEV1; TGCT cis rs2404602 0.692 rs12904198 chr15:77146978 G/A cg22467129 chr15:76604101 ETFA -0.47 -5.4 -0.44 3.28e-7 Blood metabolite levels; TGCT cis rs2742234 0.955 rs2075913 chr10:43622368 T/A cg02780029 chr10:43622663 RET -0.25 -4.91 -0.4 2.87e-6 Hirschsprung disease; TGCT cis rs7647973 0.593 rs62262730 chr3:49808274 T/G cg03060546 chr3:49711283 APEH -0.63 -5.33 -0.43 4.5e-7 Menarche (age at onset); TGCT cis rs10791097 0.694 rs4459316 chr11:130756176 T/C cg12179176 chr11:130786555 SNX19 0.83 9.92 0.67 1.94e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3749237 0.964 rs10865959 chr3:49891002 G/C cg07636037 chr3:49044803 WDR6 0.56 4.68 0.39 7.52e-6 Resting heart rate; TGCT cis rs10832963 0.924 rs10500834 chr11:18638712 A/T cg20219074 chr11:18656078 SPTY2D1 1.0 9.93 0.67 1.85e-17 Breast cancer; TGCT cis rs7267979 0.966 rs6037083 chr20:25290543 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs35306767 0.903 rs11813210 chr10:919796 G/A cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs7927592 0.763 rs10896326 chr11:68234571 T/C cg16797656 chr11:68205561 LRP5 0.26 4.54 0.38 1.29e-5 Total body bone mineral density; TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg24503407 chr1:205819492 PM20D1 0.58 8.13 0.59 3.84e-13 Menarche (age at onset); TGCT cis rs7666738 0.830 rs11940273 chr4:98979965 T/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12711979 0.509 rs10205540 chr2:3827839 A/G cg17052675 chr2:3827356 NA -0.56 -13.37 -0.77 8.42e-26 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs7666738 0.830 rs2903150 chr4:99027184 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.72 -0.62 1.51e-14 Bipolar disorder; TGCT cis rs2153535 0.541 rs9379207 chr6:8458186 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4851266 0.966 rs13026283 chr2:100842638 C/T cg22139774 chr2:100720529 AFF3 -0.34 -4.99 -0.41 2.01e-6 Educational attainment; TGCT trans rs57221529 0.709 rs72706612 chr5:561198 C/T cg25482853 chr8:67687455 SGK3 1.21 10.33 0.68 2.02e-18 Lung disease severity in cystic fibrosis; TGCT cis rs4665809 0.878 rs4665826 chr2:26367503 A/T cg22920501 chr2:26401640 FAM59B 0.72 6.19 0.49 8.23e-9 Gut microbiome composition (summer); TGCT cis rs6693567 0.545 rs11205375 chr1:150412474 C/T cg09579323 chr1:150459698 TARS2 0.52 4.62 0.38 9.56e-6 Migraine; TGCT cis rs9581857 0.547 rs17753763 chr13:28077734 A/G cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg01802117 chr1:53393560 SCP2 -0.44 -5.21 -0.42 7.54e-7 Monocyte count; TGCT cis rs12791968 0.765 rs12794846 chr11:44998943 C/T cg11846598 chr11:44996168 LOC221122 0.33 4.89 0.4 3.09e-6 Inhibitory control; TGCT cis rs524281 0.861 rs12226649 chr11:65842047 T/C cg00563793 chr11:65837595 PACS1 0.6 5.26 0.43 6.11e-7 Electroencephalogram traits; TGCT cis rs854765 0.647 rs854763 chr17:18010095 C/G cg04398451 chr17:18023971 MYO15A -0.37 -6.46 -0.5 2.14e-9 Total body bone mineral density; TGCT cis rs360798 0.512 rs2539978 chr2:63195179 T/C cg17519650 chr2:63277830 OTX1 0.62 5.73 0.46 7.22e-8 Coronary artery disease; TGCT cis rs3796352 0.764 rs11714902 chr3:53101544 G/C cg07884673 chr3:53033167 SFMBT1 0.61 6.28 0.49 5.2e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6831352 0.879 rs4699716 chr4:100066125 G/A cg12011299 chr4:100065546 ADH4 -0.43 -5.07 -0.41 1.44e-6 Alcohol dependence; TGCT cis rs72949976 1.000 rs6747328 chr2:214032156 C/G cg08319019 chr2:214017104 IKZF2 -0.83 -7.74 -0.57 2.99e-12 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs7727544 0.709 rs272852 chr5:131688767 G/A cg24060327 chr5:131705240 SLC22A5 -0.57 -6.39 -0.5 3.11e-9 Blood metabolite levels; TGCT cis rs6570726 0.837 rs419991 chr6:145864212 C/T cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs8135665 0.600 rs6519097 chr22:38451465 C/T cg13116946 chr22:38479732 SLC16A8 0.3 5.77 0.46 5.94e-8 Advanced age-related macular degeneration;Age-related macular degeneration; TGCT cis rs71636778 0.509 rs12742376 chr1:27285195 C/T cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs1401999 1.000 rs6443924 chr3:183679532 A/G cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs8070740 1.000 rs8066928 chr17:5328155 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.55 0.38 1.27e-5 Menopause (age at onset); TGCT cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg03161606 chr19:29218774 NA 0.59 5.71 0.46 7.95e-8 Methadone dose in opioid dependence; TGCT cis rs28595532 0.920 rs17257039 chr4:119603703 G/A cg11846333 chr4:119757529 SEC24D 0.95 4.68 0.39 7.54e-6 Cannabis dependence symptom count; TGCT cis rs17376456 0.542 rs10476588 chr5:93208330 C/T cg21475434 chr5:93447410 FAM172A -0.68 -5.22 -0.42 7.16e-7 Diabetic retinopathy; TGCT cis rs10782582 0.609 rs5745485 chr1:76349534 C/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg23758822 chr17:41437982 NA 0.7 6.59 0.51 1.14e-9 Menopause (age at onset); TGCT cis rs10876993 0.890 rs812304 chr12:58074853 A/C cg15848620 chr12:58087721 OS9 -0.72 -5.83 -0.46 4.52e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs79387448 0.638 rs11465670 chr2:103034440 A/G cg09003973 chr2:102972529 NA 1.27 9.82 0.66 3.37e-17 Gut microbiota (bacterial taxa); TGCT cis rs7829975 0.582 rs11783950 chr8:8597831 A/C cg15556689 chr8:8085844 FLJ10661 -0.54 -4.62 -0.38 9.37e-6 Mood instability; TGCT cis rs1691799 0.899 rs4762091 chr12:66747863 A/G cg16791601 chr12:66731901 HELB -0.29 -6.17 -0.48 8.77e-9 White blood cell count (basophil); TGCT cis rs2439831 0.867 rs2920781 chr15:43924682 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.73 4.95 0.41 2.38e-6 Lung cancer in ever smokers; TGCT cis rs3087591 0.636 rs736598 chr17:29720470 T/C cg24425628 chr17:29625626 OMG;NF1 0.4 5.87 0.47 3.67e-8 Hip circumference; TGCT cis rs4478858 0.735 rs7547897 chr1:31797593 G/A cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs79976124 0.879 rs77185357 chr6:66629070 G/A cg07460842 chr6:66804631 NA 0.57 5.23 0.43 6.84e-7 Type 2 diabetes; TGCT cis rs2996428 0.536 rs12126653 chr1:3773815 C/G cg17848003 chr1:3704513 LRRC47 0.17 4.98 0.41 2.1e-6 Red cell distribution width; TGCT cis rs12478296 0.681 rs6598999 chr2:242994405 C/A cg06360820 chr2:242988706 NA -0.62 -5.33 -0.43 4.43e-7 Obesity-related traits; TGCT cis rs10851411 0.862 rs1900921 chr15:42787144 C/A cg23803468 chr15:43513504 EPB42 0.28 5.15 0.42 1.01e-6 Glucose homeostasis traits; TGCT cis rs2730245 0.563 rs2709857 chr7:158685257 T/C cg24397884 chr7:158709396 WDR60 0.34 4.45 0.37 1.9e-5 Height; TGCT cis rs4786125 0.636 rs9932626 chr16:6917014 C/G cg03623568 chr16:6915990 A2BP1 -0.43 -6.34 -0.49 3.9e-9 Heart rate variability traits (SDNN); TGCT cis rs1862618 0.671 rs906631 chr5:56245803 C/G cg20203395 chr5:56204925 C5orf35 0.53 4.89 0.4 3.03e-6 Initial pursuit acceleration; TGCT cis rs12681287 0.752 rs10100235 chr8:87249294 A/G cg27223183 chr8:87520930 FAM82B -0.81 -5.89 -0.47 3.47e-8 Caudate activity during reward; TGCT cis rs1218582 0.803 rs7531728 chr1:154840516 C/A cg16680214 chr1:154839983 KCNN3 -0.4 -8.92 -0.63 5e-15 Prostate cancer; TGCT cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg03060546 chr3:49711283 APEH 0.5 4.7 0.39 6.82e-6 Menarche (age at onset); TGCT cis rs860554 0.705 rs832166 chr1:201255692 C/T cg01022117 chr1:201258280 PKP1 0.34 5.05 0.41 1.52e-6 Panic disorder; TGCT cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs10504229 0.636 rs77691549 chr8:58055126 G/T cg20607798 chr8:58055168 NA 0.59 4.95 0.41 2.38e-6 Developmental language disorder (linguistic errors); TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg11905131 chr22:24372483 LOC391322 0.87 10.07 0.67 8.4e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10992471 0.603 rs10820974 chr9:95211876 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -4.99 -0.41 2.03e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4273100 0.688 rs1533034 chr17:19153175 G/C cg03910582 chr17:19030146 GRAPL 0.47 5.45 0.44 2.63e-7 Schizophrenia; TGCT cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg12311346 chr5:56204834 C5orf35 -0.66 -6.67 -0.51 7.55e-10 Initial pursuit acceleration; TGCT cis rs7845219 0.544 rs10956932 chr8:95948202 C/T cg16049864 chr8:95962084 TP53INP1 0.48 5.31 0.43 5e-7 Type 2 diabetes; TGCT cis rs597539 0.690 rs578791 chr11:68625809 C/T cg21862992 chr11:68658383 NA 0.49 6.62 0.51 9.71e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4148883 0.898 rs4699726 chr4:100099513 T/C cg12011299 chr4:100065546 ADH4 0.35 5.14 0.42 1.03e-6 Alcohol dependence; TGCT trans rs7613875 0.600 rs2624832 chr3:50030858 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.32 0.6 1.31e-13 Body mass index; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg02953382 chr22:24373134 LOC391322 -0.82 -9.0 -0.63 3.34e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17030434 0.822 rs28367474 chr4:154718642 A/G cg14289246 chr4:154710475 SFRP2 -0.92 -7.76 -0.57 2.76e-12 Electrocardiographic conduction measures; TGCT cis rs79349575 0.783 rs17635252 chr17:47006950 T/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs4506170 1.000 rs72712310 chr8:128333565 G/A cg07795030 chr8:128802207 NA -0.21 -4.56 -0.38 1.23e-5 Prostate cancer; TGCT cis rs67311347 0.866 rs3214006 chr3:40352134 C/T cg13683864 chr3:40499215 RPL14 -0.91 -8.78 -0.62 1.08e-14 Renal cell carcinoma; TGCT cis rs7727544 0.716 rs6863213 chr5:131575932 C/T cg21474247 chr5:131268130 NA 0.31 4.59 0.38 1.07e-5 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg26668828 chr6:292823 DUSP22 -0.82 -8.5 -0.61 5.15e-14 Menopause (age at onset); TGCT cis rs9902453 0.780 rs57037139 chr17:28173283 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs801193 0.967 rs34356500 chr7:66236607 G/T cg00343986 chr7:65444356 GUSB 0.25 5.49 0.44 2.18e-7 Aortic root size; TGCT cis rs4851266 0.966 rs1465800 chr2:100834777 T/C cg22139774 chr2:100720529 AFF3 -0.35 -5.41 -0.44 3.1e-7 Educational attainment; TGCT cis rs295140 1.000 rs7580924 chr2:201172628 G/C cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs9914988 0.619 rs9898529 chr17:27318861 A/T cg17523868 chr17:27313033 SEZ6 -0.57 -4.84 -0.4 3.82e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs12477438 0.520 rs11123764 chr2:99750677 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg12310025 chr6:25882481 NA 0.79 8.09 0.59 4.59e-13 Blood metabolite levels; TGCT cis rs611744 1.000 rs611744 chr8:109228008 A/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs739496 0.615 rs77684561 chr12:112061723 C/T cg10833066 chr12:111807467 FAM109A 0.37 4.88 0.4 3.26e-6 Platelet count; TGCT cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs2836633 0.929 rs58120977 chr21:40037346 C/T cg12884169 chr21:40033163 ERG 0.45 4.98 0.41 2.13e-6 Coronary artery disease; TGCT cis rs4851254 0.961 rs11680586 chr2:100746207 G/T cg23118464 chr2:100721844 AFF3 0.69 5.08 0.42 1.34e-6 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.526 rs9348710 chr6:26360486 A/C cg15659132 chr6:26577336 NA -0.53 -5.47 -0.44 2.37e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs1813251 chr4:98921170 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.79e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6540559 0.611 rs61747285 chr1:210004332 G/A cg23283495 chr1:209979779 IRF6 0.6 4.5 0.37 1.54e-5 Cleft lip with or without cleft palate; TGCT cis rs7829975 0.744 rs2409092 chr8:8682192 A/T cg06636001 chr8:8085503 FLJ10661 0.69 6.25 0.49 6.14e-9 Mood instability; TGCT cis rs11098499 0.644 rs6855918 chr4:120546299 C/T cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs2836633 0.929 rs62217518 chr21:40033189 T/G cg12884169 chr21:40033163 ERG 0.43 4.69 0.39 7.03e-6 Coronary artery disease; TGCT cis rs13188771 0.651 rs59109546 chr5:100879961 G/A cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs13108904 0.517 rs7671242 chr4:1339875 G/A cg00684032 chr4:1343700 KIAA1530 0.23 4.77 0.39 4.98e-6 Obesity-related traits; TGCT cis rs3087591 0.708 rs7503922 chr17:29641935 C/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.76 0.46 6.19e-8 Hip circumference; TGCT cis rs9303401 0.659 rs62083410 chr17:56964386 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs2856321 1.000 rs11054424 chr12:11860170 C/G cg26373351 chr12:12031304 ETV6 0.21 4.43 0.37 2.01e-5 Height; TGCT cis rs7959452 0.684 rs11177615 chr12:69754189 G/A cg11871910 chr12:69753446 YEATS4 0.82 8.68 0.61 1.93e-14 Blood protein levels; TGCT cis rs2288278 0.580 rs2036764 chr17:46588331 C/T cg25032089 chr17:46643351 HOXB3 -0.42 -5.03 -0.41 1.68e-6 Hand grip strength; TGCT trans rs797680 0.796 rs797661 chr1:93687091 G/T cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7714584 1.000 rs4958843 chr5:150224924 T/C cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT trans rs4650994 0.525 rs10913567 chr1:178511941 A/C cg05059571 chr16:84539110 KIAA1609 -0.55 -11.45 -0.72 3.74e-21 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.82e-10 Electroencephalogram traits; TGCT cis rs6951245 1.000 rs11763020 chr7:1060288 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.3 -4.65 -0.39 8.4e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs35883536 1.000 rs17403857 chr1:101105216 A/C cg06223162 chr1:101003688 GPR88 0.28 4.5 0.37 1.53e-5 Monocyte count; TGCT cis rs2235642 1.000 rs2235642 chr16:1584866 T/C cg10465839 chr16:1584050 IFT140;TMEM204 -0.3 -5.09 -0.42 1.31e-6 Coronary artery disease; TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.1 0.54 8.35e-11 Prudent dietary pattern; TGCT cis rs763014 0.865 rs8909 chr16:633851 T/C cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs514406 0.584 rs12095247 chr1:53193796 A/C cg08859206 chr1:53392774 SCP2 0.35 4.98 0.41 2.11e-6 Monocyte count; TGCT cis rs6723226 0.804 rs17428810 chr2:32736043 T/C cg02381751 chr2:32503542 YIPF4 -0.55 -4.92 -0.4 2.74e-6 Intelligence (multi-trait analysis); TGCT cis rs10206020 0.921 rs72778005 chr2:1573122 C/G cg12573674 chr2:1569213 NA -0.49 -5.29 -0.43 5.44e-7 IgG glycosylation; TGCT cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.07 0.48 1.47e-8 Bipolar disorder; TGCT cis rs7223966 1.000 rs8078862 chr17:61854068 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs16952006 0.568 rs55815331 chr17:1945694 C/T cg22998033 chr17:1394477 MYO1C -0.61 -4.46 -0.37 1.8e-5 Breast cancer; TGCT cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg02725872 chr8:58115012 NA -0.39 -4.83 -0.4 3.9e-6 Developmental language disorder (linguistic errors); TGCT cis rs9910055 0.664 rs433610 chr17:42197281 A/G cg19774624 chr17:42201019 HDAC5 0.8 8.3 0.6 1.53e-13 Total body bone mineral density; TGCT cis rs2239908 0.718 rs241776 chr17:26644308 C/T cg10494684 chr17:26645200 TMEM97 0.46 4.96 0.41 2.32e-6 Blood protein levels; TGCT cis rs763121 0.853 rs9622833 chr22:39000397 G/A cg06022373 chr22:39101656 GTPBP1 0.78 7.44 0.56 1.48e-11 Menopause (age at onset); TGCT cis rs796364 0.906 rs281784 chr2:200749749 T/A cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs3812831 0.695 rs7983872 chr13:114944781 T/G cg06611532 chr13:114900021 NA 0.35 6.45 0.5 2.24e-9 Schizophrenia; TGCT cis rs12908161 0.959 rs2175567 chr15:85200946 C/G cg11189052 chr15:85197271 WDR73 0.74 6.09 0.48 1.3e-8 Schizophrenia; TGCT cis rs56399783 0.901 rs11971014 chr7:2778444 C/T cg19731401 chr7:2775893 GNA12 0.33 4.75 0.39 5.57e-6 Childhood ear infection; TGCT cis rs79387448 0.745 rs57942521 chr2:103139849 A/G cg09003973 chr2:102972529 NA 0.89 5.92 0.47 2.99e-8 Gut microbiota (bacterial taxa); TGCT trans rs629535 0.590 rs55988608 chr8:70133619 A/G cg21567404 chr3:27674614 NA -0.52 -7.76 -0.57 2.74e-12 Dupuytren's disease; TGCT cis rs7267979 1.000 rs6050631 chr20:25431749 C/T cg16686733 chr20:25566563 NINL 0.6 6.04 0.48 1.62e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs941764 0.965 rs747159 chr14:91841030 A/C cg10511902 chr14:91842949 CCDC88C -0.28 -4.79 -0.4 4.64e-6 Breast cancer; TGCT cis rs3087591 1.000 rs8082020 chr17:29694795 G/A cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.01 -0.53 1.38e-10 Hip circumference; TGCT cis rs1401999 1.000 rs6443927 chr3:183718864 A/G cg01324343 chr3:183735012 ABCC5 0.83 11.23 0.71 1.3e-20 Anterior chamber depth; TGCT cis rs1950500 0.550 rs7148384 chr14:24828814 C/T cg07162820 chr14:24837146 NFATC4 0.5 5.76 0.46 6.13e-8 Height; TGCT cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg23982607 chr1:1823379 GNB1 -0.55 -8.47 -0.61 5.97e-14 Body mass index; TGCT cis rs151997 0.671 rs27845 chr5:50197420 A/C cg06027927 chr5:50259733 NA 0.56 5.78 0.46 5.72e-8 Callous-unemotional behaviour; TGCT cis rs7772486 0.875 rs2814876 chr6:146304030 C/T cg05347473 chr6:146136440 FBXO30 0.55 5.11 0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4509693 0.843 rs4403743 chr10:102496740 A/C cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs7095607 0.785 rs10997957 chr10:69916441 G/A cg18986048 chr10:69913749 MYPN 0.45 5.03 0.41 1.68e-6 Lung function (FVC); TGCT cis rs2456568 0.570 rs1518579 chr11:93656821 A/G cg26875233 chr11:93583750 C11orf90 -0.46 -5.7 -0.46 8.27e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT cis rs9527 0.551 rs28606370 chr10:104670832 C/A cg04362960 chr10:104952993 NT5C2 0.56 4.81 0.4 4.27e-6 Arsenic metabolism; TGCT cis rs9311474 0.607 rs2015971 chr3:52546820 C/T cg10802521 chr3:52805072 NEK4 -0.72 -8.73 -0.62 1.44e-14 Electroencephalogram traits; TGCT cis rs4843747 0.671 rs74729706 chr16:88104159 C/T cg06915872 chr16:87998081 BANP -0.3 -4.55 -0.38 1.25e-5 Menopause (age at onset); TGCT cis rs1505368 0.836 rs10201067 chr2:213284411 A/G cg20637307 chr2:213403960 ERBB4 -0.49 -4.79 -0.4 4.62e-6 Symmetrical dimethylarginine levels; TGCT cis rs7043114 0.525 rs7863406 chr9:95053381 T/C cg14631576 chr9:95140430 CENPP -0.28 -4.65 -0.39 8.23e-6 Height; TGCT cis rs9611565 0.729 rs505533 chr22:41864216 A/C cg06481639 chr22:41940642 POLR3H 0.59 5.12 0.42 1.12e-6 Vitiligo; TGCT cis rs2153535 0.580 rs2184585 chr6:8474168 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1505368 0.562 rs7569142 chr2:213294557 C/T cg20637307 chr2:213403960 ERBB4 0.55 4.99 0.41 2e-6 Symmetrical dimethylarginine levels; TGCT cis rs7833790 0.963 rs28823280 chr8:82777716 G/A cg06027949 chr8:82754900 SNX16 0.64 4.54 0.38 1.32e-5 Diastolic blood pressure; TGCT cis rs492146 0.740 rs1032418 chr6:52834957 A/T cg24393602 chr6:52860404 GSTA4 0.48 4.51 0.38 1.47e-5 Epilepsy (remission after treatment); TGCT cis rs6840360 0.615 rs4696094 chr4:152465501 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.74 -0.57 2.95e-12 Intelligence (multi-trait analysis); TGCT cis rs2637266 0.729 rs846618 chr10:78545455 G/A cg18941641 chr10:78392320 NA 0.38 4.54 0.38 1.3e-5 Pulmonary function; TGCT cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg10117171 chr1:25599238 RHD -0.35 -5.64 -0.45 1.1e-7 Erythrocyte sedimentation rate; TGCT cis rs6089829 0.962 rs6089826 chr20:61668595 G/A cg08045932 chr20:61659980 NA 0.48 9.09 0.63 2.04e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs6089829 0.962 rs6062393 chr20:61663230 G/A cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs736408 0.812 rs4687654 chr3:52827566 G/A cg10802521 chr3:52805072 NEK4 -0.63 -7.07 -0.54 9.9e-11 Bipolar disorder; TGCT cis rs10501293 0.746 rs10742663 chr11:43032810 C/G cg03447554 chr11:43094025 NA 0.44 6.29 0.49 5.05e-9 Cognitive performance; TGCT cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg18876405 chr7:65276391 NA 0.35 5.66 0.45 1.01e-7 Calcium levels; TGCT cis rs12950390 0.893 rs4239166 chr17:45847329 A/G cg06532163 chr17:45867833 NA 0.34 5.31 0.43 4.82e-7 IgG glycosylation; TGCT cis rs910316 0.839 rs35977276 chr14:75637359 A/C cg11812906 chr14:75593930 NEK9 -0.74 -7.3 -0.55 3.1e-11 Height; TGCT trans rs916888 0.531 rs183211 chr17:44788310 G/A cg22968622 chr17:43663579 NA 1.0 9.57 0.65 1.41e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7772486 0.776 rs4316025 chr6:146238032 C/T cg05347473 chr6:146136440 FBXO30 -0.52 -5.16 -0.42 9.33e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs11031096 0.542 rs10835390 chr11:3981488 A/G cg18678763 chr11:4115507 RRM1 -0.41 -5.09 -0.42 1.27e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9341808 0.718 rs2322636 chr6:80897436 C/T cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs10875746 0.903 rs725454 chr12:48502100 A/G cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs1997103 1.000 rs9642578 chr7:55400320 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9818758 0.607 rs35283189 chr3:49113668 T/C cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1986116 0.773 rs12881395 chr14:77507925 C/G cg00956679 chr14:77462606 NA 0.32 4.44 0.37 1.95e-5 Sleep quality; TGCT cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1401999 1.000 rs9858774 chr3:183652736 G/A cg01324343 chr3:183735012 ABCC5 0.85 11.41 0.72 4.7e-21 Anterior chamber depth; TGCT cis rs6598955 0.671 rs11247901 chr1:26612693 T/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs7635838 0.573 rs73019547 chr3:11493323 A/C cg00170343 chr3:11313890 ATG7 0.71 6.62 0.51 9.86e-10 HDL cholesterol; TGCT cis rs2456568 0.805 rs55784864 chr11:93682887 G/A cg17595323 chr11:93583763 C11orf90 -0.46 -6.01 -0.47 1.92e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg15687855 chr3:44754131 ZNF502 -0.54 -6.68 -0.51 7.35e-10 Depressive symptoms; TGCT cis rs447921 0.861 rs12949638 chr17:74444758 C/T cg09812376 chr17:74270190 QRICH2 -0.47 -4.97 -0.41 2.17e-6 Mitochondrial DNA levels; TGCT cis rs926938 0.527 rs360681 chr1:115496741 C/G cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs1348850 1.000 rs1348850 chr2:178418575 A/G cg22681709 chr2:178499509 PDE11A -0.4 -5.41 -0.44 3.17e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs12134133 1.000 rs28371614 chr1:207505274 C/T cg02152968 chr1:207494213 CD55 0.6 4.8 0.4 4.42e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs2506889 0.553 rs7548453 chr1:10589836 A/G cg17425144 chr1:10567563 PEX14 0.52 7.41 0.55 1.68e-11 Breast cancer; TGCT cis rs7772486 0.846 rs7755440 chr6:146375906 T/C cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10465746 0.780 rs7551787 chr1:84419297 A/G cg10977910 chr1:84465055 TTLL7 0.68 7.2 0.54 5.06e-11 Obesity-related traits; TGCT cis rs71435601 0.600 rs501863 chr2:21390000 G/A cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs7568458 0.684 rs6731700 chr2:85760991 C/G cg02493740 chr2:85810744 VAMP5 -0.28 -5.37 -0.43 3.67e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs208520 0.661 rs7747492 chr6:66857788 A/T cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs1577917 0.916 rs12206726 chr6:86499716 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs9926296 0.605 rs8047486 chr16:89854025 A/T cg03388025 chr16:89894329 SPIRE2 0.5 8.7 0.62 1.73e-14 Vitiligo; TGCT cis rs3820068 0.580 rs7512308 chr1:16006604 C/A cg05660106 chr1:15850417 CASP9 0.58 5.38 0.43 3.64e-7 Systolic blood pressure; TGCT cis rs9650657 0.562 rs10090444 chr8:10745469 C/G cg27411982 chr8:10470053 RP1L1 0.21 4.64 0.38 8.87e-6 Neuroticism; TGCT cis rs13326165 0.760 rs123602 chr3:52442354 C/G cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs344364 0.552 rs388928 chr16:1909657 G/C cg01422476 chr16:1922425 C16orf73 -0.47 -4.57 -0.38 1.16e-5 Glomerular filtration rate in chronic kidney disease; TGCT cis rs35146811 0.586 rs1076237 chr7:99585441 A/C cg13334819 chr7:99746414 C7orf59 -0.65 -5.74 -0.46 6.78e-8 Coronary artery disease; TGCT cis rs6089829 0.889 rs6090206 chr20:61668363 G/A cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT trans rs2243480 1.000 rs1796220 chr7:66062100 C/T cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs1949733 0.666 rs3103070 chr4:8508825 A/G cg11789530 chr4:8429930 ACOX3 -0.61 -5.69 -0.46 8.62e-8 Response to antineoplastic agents; TGCT cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg22105103 chr4:187893119 NA 0.33 4.62 0.38 9.41e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12712073 0.845 rs1370353 chr2:100764824 G/C cg07810366 chr2:100720526 AFF3 -0.36 -5.31 -0.43 4.95e-7 Intelligence (multi-trait analysis); TGCT cis rs9300255 0.602 rs2695479 chr12:123689386 T/C cg00376283 chr12:123451042 ABCB9 0.72 4.99 0.41 2e-6 Neutrophil percentage of white cells; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.42 6.05 0.48 1.57e-8 Lymphocyte counts; TGCT cis rs35146811 0.735 rs1727138 chr7:99815247 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs11748023 0.605 rs155948 chr5:139519181 A/G cg01081189 chr5:139537190 NA -0.25 -4.46 -0.37 1.83e-5 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.850 rs8042868 chr15:43939642 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.91 6.47 0.5 2.04e-9 Lung cancer in ever smokers; TGCT cis rs651907 0.535 rs17412601 chr3:101499275 T/C cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.52 -0.51 1.56e-9 Colorectal cancer; TGCT cis rs921968 0.541 rs6720403 chr2:219294258 A/C cg02176678 chr2:219576539 TTLL4 -0.45 -6.45 -0.5 2.25e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs739496 0.615 rs4767939 chr12:112206895 A/G cg10833066 chr12:111807467 FAM109A 0.37 5.02 0.41 1.74e-6 Platelet count; TGCT cis rs2836950 0.545 rs8132143 chr21:40584258 A/T cg11890956 chr21:40555474 PSMG1 -0.68 -6.75 -0.52 5.1e-10 Menarche (age at onset); TGCT cis rs4851254 0.961 rs11682173 chr2:100759810 C/T cg23118464 chr2:100721844 AFF3 0.68 5.01 0.41 1.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7523273 0.597 rs56075814 chr1:207975949 T/C cg22525895 chr1:207977042 MIR29B2 -0.45 -6.64 -0.51 8.76e-10 Schizophrenia; TGCT cis rs7666738 0.830 rs17027058 chr4:98864671 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.38 0.43 3.58e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9640161 0.750 rs1047586 chr7:150035459 T/G cg10018233 chr7:150070692 REPIN1 0.31 4.45 0.37 1.88e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs912057 0.526 rs746453 chr6:6734221 C/A cg06612196 chr6:6737390 NA 0.48 6.93 0.53 2.05e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs116095464 0.558 rs28418643 chr5:240859 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs11924390 0.789 rs822366 chr3:186452490 A/G cg12454167 chr3:186435060 KNG1 0.44 6.91 0.53 2.24e-10 Adiponectin levels; TGCT cis rs62064224 0.614 rs4794923 chr17:30763009 G/A cg18200150 chr17:30822561 MYO1D 0.43 5.31 0.43 4.86e-7 Schizophrenia; TGCT cis rs7010267 0.740 rs7464496 chr8:119954842 T/C cg17171407 chr8:119960777 TNFRSF11B 0.25 4.45 0.37 1.86e-5 Total body bone mineral density (age 45-60); TGCT cis rs7681440 0.904 rs28777703 chr4:90769924 A/G cg01966878 chr4:90757139 SNCA 0.25 4.5 0.37 1.54e-5 Dementia with Lewy bodies; TGCT cis rs7582180 0.739 rs11123824 chr2:100924029 G/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.790 rs2249386 chr6:146186611 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.06 0.41 1.47e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3806843 0.576 rs550475 chr5:140273528 G/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.42 -5.05 -0.41 1.52e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs28595532 0.920 rs114547492 chr4:119773078 G/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs4819052 1.000 rs4819052 chr21:46699777 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.97 7.98 0.58 8.44e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3820068 0.705 rs57238793 chr1:15890029 A/G cg05660106 chr1:15850417 CASP9 1.13 13.14 0.76 3.06e-25 Systolic blood pressure; TGCT cis rs7267979 1.000 rs2424713 chr20:25418482 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9914988 0.565 rs34039488 chr17:27320232 G/A cg16968985 chr17:27313254 SEZ6 -0.35 -4.47 -0.37 1.75e-5 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7819412 0.642 rs11250117 chr8:10972740 C/A cg03192020 chr8:11204681 TDH -0.5 -4.57 -0.38 1.17e-5 Triglycerides; TGCT cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.81e-9 Cognitive function; TGCT cis rs26868 0.816 rs26872 chr16:2247644 C/T cg26873644 chr16:2260806 C16orf79 -0.24 -4.81 -0.4 4.36e-6 Height; TGCT cis rs1552244 0.554 rs6762594 chr3:9995516 G/A cg00149659 chr3:10157352 C3orf10 0.66 4.89 0.4 3.04e-6 Alzheimer's disease; TGCT cis rs2224391 0.628 rs1609808 chr6:5246333 C/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs1348850 0.519 rs1544002 chr2:178529534 C/T cg22681709 chr2:178499509 PDE11A -0.47 -5.96 -0.47 2.43e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs896854 0.812 rs4582532 chr8:95969257 G/A cg23172400 chr8:95962367 TP53INP1 -0.4 -6.65 -0.51 8.46e-10 Type 2 diabetes; TGCT cis rs4727027 0.870 rs1105261 chr7:148794442 T/G cg23583168 chr7:148888333 NA -0.71 -8.93 -0.63 4.74e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg07617317 chr6:118971624 C6orf204 0.51 5.52 0.44 1.92e-7 Renal cell carcinoma; TGCT cis rs589448 0.902 rs315124 chr12:69771727 G/A cg20891283 chr12:69753455 YEATS4 0.91 10.46 0.68 9.81e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg00024416 chr22:24240387 NA 0.24 4.6 0.38 1.02e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6558530 0.931 rs4639549 chr8:1708044 A/G cg09410841 chr8:1729607 CLN8 0.91 10.31 0.68 2.23e-18 Systolic blood pressure; TGCT cis rs2243480 0.901 rs34807232 chr7:65965133 G/A cg20637647 chr7:64974828 NA 0.91 5.37 0.43 3.74e-7 Diabetic kidney disease; TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg07157834 chr1:205819609 PM20D1 0.49 8.25 0.6 1.92e-13 Menarche (age at onset); TGCT cis rs2180341 0.618 rs4502958 chr6:127593113 G/A cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs447735 0.565 rs10852626 chr16:89914633 T/G cg27121462 chr16:89883253 FANCA 0.56 5.02 0.41 1.77e-6 Hemoglobin concentration; TGCT cis rs10892173 0.818 rs7947524 chr11:117671091 C/T cg07621104 chr11:117668040 DSCAML1 0.46 4.81 0.4 4.21e-6 Myopia; TGCT cis rs7103648 0.966 rs10769263 chr11:47417183 A/C cg20307385 chr11:47447363 PSMC3 1.0 11.81 0.73 4.88e-22 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs12620999 0.774 rs7584900 chr2:237957112 T/G cg23555395 chr2:238036564 NA 0.27 4.76 0.39 5.37e-6 Systemic lupus erythematosus; TGCT cis rs68170813 0.559 rs7981 chr7:106843133 G/C cg02696742 chr7:106810147 HBP1 -0.69 -5.73 -0.46 7.17e-8 Coronary artery disease; TGCT cis rs8031584 0.652 rs2691683 chr15:31135060 A/G cg08109568 chr15:31115862 NA 0.38 5.03 0.41 1.67e-6 Huntington's disease progression; TGCT cis rs9914988 0.673 rs9890212 chr17:27169890 G/C cg20469991 chr17:27169893 C17orf63 -0.71 -4.99 -0.41 2.02e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2439831 0.867 rs28729853 chr15:43673680 A/C cg02155558 chr15:43621948 ADAL;LCMT2 1.04 8.35 0.6 1.16e-13 Lung cancer in ever smokers; TGCT cis rs929354 1.000 rs1182378 chr7:157048322 T/C cg05182265 chr7:156933206 UBE3C 0.31 6.45 0.5 2.23e-9 Body mass index; TGCT cis rs611744 0.967 rs645241 chr8:109190963 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs780096 0.546 rs715325 chr2:27725572 C/A cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.44 -0.37 1.98e-5 Total body bone mineral density; TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg16145915 chr7:1198662 ZFAND2A -0.62 -8.26 -0.6 1.9e-13 Longevity;Endometriosis; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs2361718 0.521 rs2361724 chr17:78099114 G/A cg21238619 chr17:78079768 GAA -0.37 -4.74 -0.39 5.86e-6 Yeast infection; TGCT cis rs12497850 0.931 rs4974079 chr3:48906469 T/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs6770219 0.516 rs6794762 chr3:186136514 G/T cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs2797160 1.000 rs1935774 chr6:125996661 A/G cg05901451 chr6:126070800 HEY2 0.74 6.67 0.51 7.64e-10 Endometrial cancer; TGCT cis rs4961252 0.545 rs1107258 chr8:142104071 G/A cg09914555 chr8:142094789 NA -0.38 -5.67 -0.45 9.51e-8 Isovolumetric relaxation time;Response to interferon beta therapy; TGCT cis rs12681288 0.550 rs73176529 chr8:962283 G/C cg04851639 chr8:1020857 NA -0.3 -5.08 -0.41 1.36e-6 Schizophrenia; TGCT cis rs2249625 0.504 rs2496508 chr6:72891398 A/G cg08500200 chr6:72892038 RIMS1 -0.43 -4.59 -0.38 1.07e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs1461503 0.512 rs4293126 chr11:122804133 A/G cg14473756 chr11:122847823 NA 0.44 4.69 0.39 7.1e-6 Menarche (age at onset); TGCT cis rs354033 1.000 rs354043 chr7:149297332 C/T cg24335155 chr7:149193227 ZNF746 0.32 4.56 0.38 1.19e-5 Multiple sclerosis; TGCT cis rs7714584 1.000 rs1428554 chr5:150257616 A/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.86 8.45 0.6 6.61e-14 Intelligence (multi-trait analysis); TGCT cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg04608855 chr19:58913158 NA -0.5 -4.73 -0.39 6.09e-6 Uric acid clearance; TGCT cis rs12620999 0.941 rs58678188 chr2:237971036 C/A cg23555395 chr2:238036564 NA 0.28 4.82 0.4 4.13e-6 Systemic lupus erythematosus; TGCT cis rs4780401 0.539 rs62040604 chr16:11803641 G/A cg01061890 chr16:11836724 TXNDC11 -0.57 -5.41 -0.44 3.06e-7 Rheumatoid arthritis; TGCT cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg10802521 chr3:52805072 NEK4 -0.7 -8.53 -0.61 4.33e-14 Cognitive function; TGCT cis rs9500256 0.655 rs12210275 chr6:58331759 C/T cg16251399 chr6:58287822 GUSBL2 0.56 4.74 0.39 5.76e-6 Eosinophilic esophagitis (pediatric); TGCT cis rs10504229 0.906 rs28447218 chr8:58170813 T/G cg22535103 chr8:58192502 C8orf71 -0.39 -5.19 -0.42 8.44e-7 Developmental language disorder (linguistic errors); TGCT cis rs941408 1.000 rs1736181 chr19:2797703 C/T cg06609049 chr19:2785107 THOP1 0.8 7.68 0.57 4.14e-12 Total cholesterol levels; TGCT cis rs17331151 0.541 rs4687676 chr3:52890418 C/T cg12962167 chr3:53033115 SFMBT1 -0.42 -4.78 -0.39 4.81e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3125734 0.633 rs3765002 chr10:64006124 G/T cg05499367 chr10:63213510 TMEM26 -0.33 -4.46 -0.37 1.78e-5 Rheumatoid arthritis; TGCT cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.07e-9 Type 2 diabetes; TGCT cis rs35306767 0.669 rs2101051 chr10:1158791 G/T cg18964960 chr10:1102726 WDR37 0.66 4.51 0.38 1.46e-5 Eosinophil percentage of granulocytes; TGCT cis rs6060960 0.502 rs15817 chr20:30193538 A/G cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.42e-6 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs494003 1.000 rs578056 chr11:65514874 C/T cg04293602 chr11:65553660 OVOL1 0.36 4.62 0.38 9.28e-6 Systemic lupus erythematosus; TGCT cis rs7824557 0.628 rs17797894 chr8:11212081 A/G cg21775007 chr8:11205619 TDH 0.73 7.03 0.53 1.23e-10 Retinal vascular caliber; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg12034118 chr1:209979487 IRF6 0.72 8.01 0.58 7.19e-13 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs218265 0.764 rs218237 chr4:55394172 C/T cg20208633 chr4:55405888 NA -0.56 -4.6 -0.38 1.03e-5 Sum neutrophil eosinophil counts;Myeloid white cell count;High light scatter reticulocyte percentage of red cells;Mean corpuscular volume;Reticulocyte fraction of red cells;Red blood cell count;Immature fraction of reticulocytes;Sum basophil neutrophil counts;Granulocyte count;White blood cell count;Neutrophil count;Mean corpuscular hemoglobin;Plateletcrit; TGCT cis rs453301 0.624 rs6987558 chr8:8862521 C/G cg06636001 chr8:8085503 FLJ10661 0.76 6.73 0.52 5.5e-10 Joint mobility (Beighton score); TGCT cis rs734999 0.545 rs9970196 chr1:2574078 T/C cg18854424 chr1:2615690 NA -0.46 -5.31 -0.43 4.97e-7 Ulcerative colitis; TGCT cis rs4851266 0.966 rs10496345 chr2:100817619 T/G cg22139774 chr2:100720529 AFF3 -0.36 -5.38 -0.44 3.55e-7 Educational attainment; TGCT cis rs8077889 0.917 rs8081646 chr17:41893360 T/C cg26893861 chr17:41843967 DUSP3 1.11 13.17 0.76 2.53e-25 Triglycerides; TGCT cis rs28374715 0.528 rs7181982 chr15:41623020 C/G cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.93 -0.8 1.76e-29 Ulcerative colitis; TGCT cis rs2688608 0.592 rs11000757 chr10:75486815 T/C cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs1008375 1.000 rs7697889 chr4:17617961 G/T cg16339924 chr4:17578868 LAP3 0.6 4.97 0.41 2.14e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7582180 0.629 rs4851297 chr2:100949571 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs2486288 0.656 rs6493144 chr15:45573489 C/G cg14582100 chr15:45693742 SPATA5L1 0.47 5.65 0.45 1.04e-7 Glomerular filtration rate; TGCT cis rs2224391 1.000 rs2753247 chr6:5261987 A/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -6.05 -0.48 1.61e-8 Height; TGCT cis rs62064224 0.589 rs6505295 chr17:30687522 G/C cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.66e-6 Schizophrenia; TGCT cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg23758822 chr17:41437982 NA 0.71 6.83 0.52 3.46e-10 Menopause (age at onset); TGCT cis rs9611565 0.765 rs727563 chr22:41867377 C/T cg17554472 chr22:41940697 POLR3H 0.47 5.07 0.41 1.43e-6 Vitiligo; TGCT cis rs1865760 0.663 rs9467656 chr6:25993559 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.7 6.91 0.53 2.26e-10 Height; TGCT cis rs4927850 1.000 rs7614767 chr3:195753451 C/T cg02975922 chr3:195473998 MUC4 -0.24 -5.74 -0.46 6.87e-8 Pancreatic cancer; TGCT cis rs763121 0.853 rs6001188 chr22:39062194 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.9e-12 Menopause (age at onset); TGCT cis rs1153858 0.943 rs4774580 chr15:45652086 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7044106 0.537 rs4434680 chr9:123489688 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 5.55 0.45 1.62e-7 Hip circumference adjusted for BMI; TGCT cis rs6582630 0.555 rs35284307 chr12:38509999 T/G cg26384229 chr12:38710491 ALG10B 0.85 7.86 0.58 1.55e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs360798 0.532 rs7573756 chr2:62990637 G/A cg17519650 chr2:63277830 OTX1 -0.58 -5.06 -0.41 1.48e-6 Coronary artery disease; TGCT cis rs9916302 0.904 rs4795357 chr17:37569551 T/C cg15445000 chr17:37608096 MED1 0.35 5.05 0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg18252515 chr7:66147081 NA 1.17 7.17 0.54 5.94e-11 Diabetic kidney disease; TGCT cis rs7678296 0.649 rs77896458 chr4:37237843 A/G cg06805348 chr4:37245195 KIAA1239 0.57 4.78 0.39 4.81e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs28595532 0.841 rs55744948 chr4:119769243 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg23172400 chr8:95962367 TP53INP1 -0.36 -6.15 -0.48 9.57e-9 Type 2 diabetes; TGCT trans rs7618501 0.633 rs6446189 chr3:50008566 A/G cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.85e-16 Intelligence (multi-trait analysis); TGCT cis rs75686122 0.892 rs74869978 chr8:104678453 T/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7043114 0.525 rs710162 chr9:95059790 A/T cg13798575 chr9:95087839 CENPP;NOL8 0.54 5.38 0.43 3.6e-7 Height; TGCT cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs10746514 0.833 rs867844 chr1:232266278 A/T cg09506761 chr1:232265262 NA 0.5 5.11 0.42 1.17e-6 Response to statin therapy; TGCT cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs4722585 0.533 rs6964215 chr7:26196819 G/A cg07876897 chr7:26191696 NFE2L3 0.39 5.2 0.42 8.14e-7 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs422249 0.512 rs174578 chr11:61605499 T/A cg20584555 chr11:61717780 BEST1 -0.23 -4.46 -0.37 1.82e-5 Trans fatty acid levels; TGCT cis rs9322193 0.923 rs7740278 chr6:149961252 C/T cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs8044995 0.563 rs56220628 chr16:68384837 G/A cg05110241 chr16:68378359 PRMT7 -0.35 -4.44 -0.37 1.94e-5 Schizophrenia; TGCT cis rs10276381 1.000 rs10263857 chr7:28187284 C/G cg23620719 chr7:28220237 JAZF1 1.01 5.82 0.46 4.75e-8 Crohn's disease; TGCT cis rs1901167 0.908 rs1061443 chr5:40982622 G/T cg02441090 chr5:41871058 OXCT1 -0.31 -4.61 -0.38 9.86e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4824093 0.610 rs13340054 chr22:50311726 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.07 -5.93 -0.47 2.87e-8 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.28 0.49 5.19e-9 Schizophrenia; TGCT cis rs875971 0.964 rs1643388 chr7:65844562 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs13405699 1 rs13405699 chr2:174605633 A/C cg04180623 chr2:174057774 ZAK -0.32 -4.56 -0.38 1.2e-5 Male-pattern baldness; TGCT cis rs13108904 0.539 rs13140926 chr4:1340939 G/A cg03303774 chr4:1407052 NA 0.38 5.9 0.47 3.24e-8 Obesity-related traits; TGCT cis rs9611565 0.877 rs3817999 chr22:41747717 A/G cg06634786 chr22:41940651 POLR3H 0.81 7.97 0.58 8.93e-13 Vitiligo; TGCT cis rs9527 0.615 rs10883804 chr10:104706520 G/A cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs4595586 0.545 rs969468 chr12:39367278 A/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs473651 0.904 rs10929275 chr2:239323169 A/G cg08773314 chr2:239334832 ASB1 0.47 7.86 0.58 1.62e-12 Multiple system atrophy; TGCT cis rs6940638 0.662 rs6915678 chr6:27235866 T/G cg15659132 chr6:26577336 NA -0.59 -5.52 -0.44 1.87e-7 Intelligence (multi-trait analysis); TGCT cis rs9942416 0.660 rs194137 chr5:74978857 G/A cg19683494 chr5:74908142 NA -0.59 -6.29 -0.49 4.99e-9 Age-related disease endophenotypes; TGCT cis rs4819052 0.851 rs9977178 chr21:46664531 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.08 0.42 1.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs35150201 1.000 rs35150201 chr7:135346262 T/G cg23117316 chr7:135346802 PL-5283 -0.45 -4.74 -0.39 5.77e-6 Plateletcrit;Mean corpuscular hemoglobin;Mean platelet volume; TGCT cis rs7428 0.545 rs4832163 chr2:85541083 T/C cg24342717 chr2:85555507 TGOLN2 -0.48 -8.35 -0.6 1.15e-13 Ear protrusion; TGCT cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg09904177 chr6:26538194 HMGN4 0.66 6.33 0.49 3.99e-9 Intelligence (multi-trait analysis); TGCT cis rs3820928 0.935 rs12151597 chr2:227859224 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs9296092 0.538 rs75082458 chr6:33524792 C/T cg13560919 chr6:33536144 NA -0.22 -4.83 -0.4 3.97e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6500602 0.653 rs3747579 chr16:4445327 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.27 -4.54 -0.38 1.29e-5 Schizophrenia; TGCT cis rs9560113 1.000 rs11620313 chr13:112179363 G/A cg14154082 chr13:112174009 NA 0.37 4.96 0.41 2.28e-6 Menarche (age at onset); TGCT cis rs1799949 1.000 rs915945 chr17:41179864 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs2742234 0.955 rs1272142 chr10:43695484 G/T cg02780029 chr10:43622663 RET -0.26 -5.09 -0.42 1.28e-6 Hirschsprung disease; TGCT cis rs514406 0.861 rs1571979 chr1:53237526 G/A cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs514406 0.525 rs269291 chr1:53189297 C/T cg04995860 chr1:53192072 ZYG11B -0.4 -4.49 -0.37 1.59e-5 Monocyte count; TGCT cis rs3806843 0.548 rs246057 chr5:140325583 A/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1903068 0.886 rs1551644 chr4:55994266 A/T cg01777861 chr4:56023843 NA 0.56 6.43 0.5 2.54e-9 Endometriosis; TGCT cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs3849570 0.643 rs11705789 chr3:81969196 G/T cg07356753 chr3:81810745 GBE1 -0.72 -6.75 -0.52 5e-10 Waist circumference;Body mass index; TGCT cis rs35146811 0.735 rs858512 chr7:99824453 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs425277 0.583 rs10910046 chr1:2041155 C/T cg03732007 chr1:2071316 PRKCZ -0.27 -6.02 -0.48 1.81e-8 Height; TGCT cis rs394563 0.726 rs6906384 chr6:149664540 G/A cg03678062 chr6:149772716 ZC3H12D 0.44 5.79 0.46 5.49e-8 Dupuytren's disease; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg18538332 chr22:24372958 LOC391322 -0.96 -10.62 -0.69 3.95e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs1496653 0.602 rs35218978 chr3:23429585 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs7412746 0.658 rs11582281 chr1:150826831 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 4.75 0.39 5.55e-6 Melanoma; TGCT cis rs546131 0.642 rs566798 chr11:34852277 A/G cg06937548 chr11:34938143 PDHX;APIP -0.54 -4.63 -0.38 9.24e-6 Lung disease severity in cystic fibrosis; TGCT cis rs11249608 0.548 rs11951738 chr5:178491228 G/A cg01312482 chr5:178451176 ZNF879 -0.49 -4.8 -0.4 4.4e-6 Pubertal anthropometrics; TGCT trans rs12145833 1.000 rs76473275 chr1:243460555 T/C cg15780870 chr12:130953802 RIMBP2 0.48 6.73 0.52 5.57e-10 Obesity (early onset extreme); TGCT cis rs6901004 0.803 rs1322214 chr6:111480045 T/A cg15721981 chr6:111408429 SLC16A10 -0.51 -4.53 -0.38 1.35e-5 Blood metabolite levels; TGCT cis rs4951018 0.821 rs11240547 chr1:205632932 A/G cg07167872 chr1:205819463 PM20D1 0.39 4.61 0.38 9.91e-6 Prostate-specific antigen levels; TGCT cis rs10464059 0.575 rs6601110 chr5:179759928 T/C cg25959792 chr5:179775488 GFPT2 0.3 4.48 0.37 1.65e-5 Parkinson's disease; TGCT trans rs459571 1.000 rs2810489 chr9:136922700 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.82 -8.78 -0.62 1.08e-14 Platelet distribution width; TGCT cis rs8072100 0.727 rs4794052 chr17:45769236 T/C cg08085267 chr17:45401833 C17orf57 -0.43 -4.82 -0.4 4.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs926938 0.584 rs360606 chr1:115391769 C/T cg12756093 chr1:115239321 AMPD1 0.41 5.87 0.47 3.69e-8 Autism; TGCT cis rs17376456 0.825 rs17372725 chr5:93135588 C/A cg25358565 chr5:93447407 FAM172A 0.91 8.17 0.59 2.97e-13 Diabetic retinopathy; TGCT trans rs6069325 0.529 rs6024210 chr20:54139554 A/G cg26869512 chr4:8389770 ACOX3 0.47 6.92 0.53 2.12e-10 Motion sickness; TGCT cis rs10794720 0.748 rs11250275 chr10:1171823 A/G cg08668510 chr10:1095578 IDI1 -1.14 -5.18 -0.42 8.73e-7 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease; TGCT cis rs7617773 0.743 rs6804986 chr3:48363595 A/G cg11946769 chr3:48343235 NME6 0.79 6.83 0.52 3.32e-10 Coronary artery disease; TGCT cis rs1153858 0.943 rs8038342 chr15:45651537 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs8062405 0.965 rs56040780 chr16:28861881 C/T cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs78487399 0.808 rs75934770 chr2:43659694 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.69 0.39 7.08e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2463822 0.858 rs2513037 chr11:62084822 A/T cg23876832 chr11:62092739 NA -0.63 -4.63 -0.38 8.94e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg08219700 chr8:58056026 NA 0.3 4.64 0.38 8.89e-6 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.846 rs6899900 chr6:145883873 T/G cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12451471 0.529 rs2278620 chr17:78083565 G/A cg06718696 chr17:78121285 EIF4A3 0.71 5.89 0.47 3.42e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs877282 0.853 rs11253332 chr10:755262 G/C cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs7830933 0.955 rs1550280 chr8:23601830 C/T cg04349084 chr8:23602677 NA 0.25 4.9 0.4 2.96e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs4851266 1.000 rs1122231 chr2:100834546 C/T cg07810366 chr2:100720526 AFF3 -0.39 -5.73 -0.46 7.19e-8 Educational attainment; TGCT cis rs2721195 0.845 rs4244611 chr8:145739924 G/A cg11211951 chr8:145729740 GPT 0.27 6.58 0.51 1.16e-9 Age at first birth; TGCT cis rs9330316 0.632 rs34557890 chr2:110316208 G/A cg25199208 chr2:109402912 CCDC138 -0.42 -4.56 -0.38 1.19e-5 Schizophrenia; TGCT cis rs9560113 0.573 rs1888304 chr13:112242454 A/G cg10483660 chr13:112241077 NA 0.36 5.51 0.44 1.97e-7 Menarche (age at onset); TGCT cis rs858239 0.539 rs6956828 chr7:23187347 A/G cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9914988 0.943 rs4795459 chr17:27113726 G/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs10193935 0.901 rs62142561 chr2:42477808 G/C cg27598129 chr2:42591480 NA -0.39 -5.43 -0.44 2.86e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1322512 0.760 rs818451 chr6:152924673 T/G cg03415253 chr6:152958462 SYNE1 -0.56 -5.28 -0.43 5.72e-7 Tonometry; TGCT cis rs7829975 0.617 rs4841071 chr8:8791144 G/T cg00184457 chr8:8946301 NA 0.22 4.47 0.37 1.76e-5 Mood instability; TGCT cis rs514406 0.861 rs4926576 chr1:53226775 C/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.41 2.55e-6 Monocyte count; TGCT cis rs1153858 1.000 rs16942568 chr15:45677390 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg24531977 chr5:56204891 C5orf35 0.97 9.1 0.63 1.92e-15 Initial pursuit acceleration; TGCT cis rs3734905 1.000 rs3734905 chr6:169958982 G/A cg20469989 chr6:170102314 C6orf120;WDR27 -0.88 -4.67 -0.39 7.59e-6 HIV-1 control; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg11905131 chr22:24372483 LOC391322 -0.93 -10.65 -0.69 3.41e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9303401 0.659 rs35928756 chr17:56702652 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs6121246 0.529 rs73235789 chr20:30196148 T/C cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.39e-6 Mean corpuscular hemoglobin; TGCT cis rs7336332 0.600 rs9579083 chr13:28017270 G/C cg22138327 chr13:27999177 GTF3A 0.83 6.64 0.51 9e-10 Weight; TGCT cis rs7043114 0.525 rs6479419 chr9:95110002 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.54 -0.45 1.72e-7 Height; TGCT cis rs9443189 0.570 rs6931578 chr6:76272310 C/T cg01950844 chr6:76311363 SENP6 0.98 6.08 0.48 1.35e-8 Prostate cancer; TGCT cis rs1903068 0.719 rs73236106 chr4:55996712 C/T cg01777861 chr4:56023843 NA 0.53 6.16 0.48 9.28e-9 Endometriosis; TGCT cis rs9883204 0.855 rs11719201 chr3:123068744 C/T cg04890266 chr3:123102914 ADCY5 0.37 4.99 0.41 1.98e-6 Birth weight; TGCT cis rs2120019 0.608 rs8042558 chr15:75320433 G/T cg17294928 chr15:75287854 SCAMP5 -0.92 -7.8 -0.57 2.22e-12 Blood trace element (Zn levels); TGCT cis rs5769765 0.874 rs11703411 chr22:50258751 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.01 -0.48 1.89e-8 Schizophrenia; TGCT cis rs7178424 0.516 rs11635621 chr15:62322646 T/C cg00456672 chr15:62358751 C2CD4A -0.29 -4.46 -0.37 1.84e-5 Height; TGCT cis rs11190604 0.767 rs10736150 chr10:102195341 G/A cg16342193 chr10:102329863 NA 0.4 4.99 0.41 2.04e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9653442 0.900 rs10194635 chr2:100834217 T/A cg22139774 chr2:100720529 AFF3 -0.39 -6.27 -0.49 5.59e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10411936 1.000 rs873636 chr19:16514771 C/T cg19006008 chr19:16999768 F2RL3 0.27 4.66 0.39 8.03e-6 White blood cell count;Multiple sclerosis; TGCT cis rs11098499 0.863 rs1480936 chr4:120462861 C/T cg09307838 chr4:120376055 NA 0.7 6.6 0.51 1.06e-9 Corneal astigmatism; TGCT cis rs270601 0.690 rs162904 chr5:131595784 C/T cg24060327 chr5:131705240 SLC22A5 0.62 6.34 0.49 3.83e-9 Acylcarnitine levels; TGCT cis rs9985766 0.958 rs4259040 chr4:151002847 T/G cg05926478 chr4:151174724 DCLK2 -0.24 -4.72 -0.39 6.32e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs2228479 0.867 rs12930606 chr16:89946682 A/G cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg08125733 chr17:73851984 WBP2 1.17 12.85 0.76 1.47e-24 Psoriasis; TGCT cis rs9329289 0.510 rs9733402 chr10:2551532 G/A cg07014206 chr10:2547000 NA -0.28 -4.64 -0.38 8.6e-6 Age-related hearing impairment; TGCT cis rs539096 0.500 rs2527776 chr1:44345292 G/A cg12908607 chr1:44402522 ARTN -0.7 -8.79 -0.62 1.01e-14 Intelligence (multi-trait analysis); TGCT cis rs941408 0.515 rs12610096 chr19:2778129 C/T cg06609049 chr19:2785107 THOP1 1.17 13.17 0.76 2.56e-25 Total cholesterol levels; TGCT cis rs7582180 0.663 rs6542944 chr2:100988038 T/C cg14675211 chr2:100938903 LONRF2 0.48 4.6 0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.941 rs6735145 chr2:26270302 T/C cg04944784 chr2:26401820 FAM59B -0.66 -5.93 -0.47 2.85e-8 Gut microbiome composition (summer); TGCT cis rs9733 0.596 rs12403255 chr1:150660412 C/T cg04414720 chr1:150670196 GOLPH3L 0.38 5.02 0.41 1.77e-6 Tonsillectomy; TGCT cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg20203395 chr5:56204925 C5orf35 0.57 4.89 0.4 3.08e-6 Initial pursuit acceleration; TGCT cis rs13064447 0.967 rs12637499 chr3:12756946 C/T cg20675869 chr3:12750130 NA 0.19 4.9 0.4 2.97e-6 Major depression and alcohol dependence; TGCT cis rs67478160 0.643 rs4906369 chr14:104242458 T/C cg26031613 chr14:104095156 KLC1 -0.63 -6.57 -0.51 1.25e-9 Schizophrenia; TGCT cis rs28595532 0.920 rs116366070 chr4:119764180 A/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs700651 0.685 rs976180 chr2:198880443 C/T cg00792783 chr2:198669748 PLCL1 -0.58 -5.04 -0.41 1.64e-6 Intracranial aneurysm; TGCT cis rs6990255 0.681 rs1495236 chr8:34119750 G/T cg19906737 chr8:33370681 C8orf41 0.75 4.61 0.38 9.76e-6 Bipolar disorder;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17473412 0.609 rs74841787 chr5:122870294 G/A cg15125798 chr5:122621645 NA -0.54 -4.86 -0.4 3.42e-6 Total body bone mineral density; TGCT cis rs3820068 0.705 rs11587541 chr1:15899478 T/C cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs10114408 0.959 rs10123414 chr9:96646136 T/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9549367 0.789 rs2287250 chr13:113889474 C/T cg00898013 chr13:113819073 PROZ 0.41 5.12 0.42 1.12e-6 Platelet distribution width; TGCT cis rs11098499 0.690 rs34818745 chr4:120257055 T/C cg09307838 chr4:120376055 NA 0.68 6.49 0.5 1.88e-9 Corneal astigmatism; TGCT cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs17253792 0.822 rs78826571 chr14:56048906 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3733585 0.699 rs7677710 chr4:9969517 T/G cg11266682 chr4:10021025 SLC2A9 -0.59 -7.85 -0.58 1.7e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7291412 0.662 rs12159707 chr22:46449891 G/A cg05468064 chr22:46423449 NA 0.48 4.58 0.38 1.12e-5 Dupuytren's disease;Subjective well-being; TGCT cis rs1153858 0.945 rs16943246 chr15:45720597 G/A cg26924012 chr15:45694286 SPATA5L1 1.04 13.15 0.76 2.81e-25 Homoarginine levels; TGCT cis rs6545883 0.929 rs13413337 chr2:61747123 A/G cg15711740 chr2:61764176 XPO1 -0.52 -4.78 -0.39 4.78e-6 Tuberculosis; TGCT cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg25036284 chr2:26402008 FAM59B -0.58 -4.61 -0.38 1.01e-5 Gut microbiome composition (summer); TGCT cis rs4767364 0.922 rs7300252 chr12:112430346 C/T cg10833066 chr12:111807467 FAM109A 0.32 5.05 0.41 1.52e-6 Oral cavity and pharyngeal cancer; TGCT cis rs11578119 0.866 rs12133110 chr1:170353436 G/A cg09767346 chr1:170501363 GORAB 0.61 4.61 0.38 9.8e-6 Male-pattern baldness; TGCT cis rs981844 0.857 rs62325142 chr4:154717790 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.9 0.62 5.71e-15 Response to statins (LDL cholesterol change); TGCT cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg20203395 chr5:56204925 C5orf35 -0.56 -4.67 -0.39 7.83e-6 Initial pursuit acceleration; TGCT trans rs57221529 0.766 rs12518859 chr5:587432 C/T cg11887960 chr12:57824829 NA 1.14 9.3 0.64 6.29e-16 Lung disease severity in cystic fibrosis; TGCT cis rs10791323 0.569 rs10750541 chr11:133713189 A/C cg15485101 chr11:133734466 NA -0.42 -5.52 -0.44 1.86e-7 Childhood ear infection; TGCT cis rs12497850 0.931 rs7643368 chr3:48992855 T/G cg07636037 chr3:49044803 WDR6 0.96 10.39 0.68 1.45e-18 Parkinson's disease; TGCT cis rs1865760 1.000 rs6905887 chr6:25912103 T/C cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs4242434 0.927 rs13271626 chr8:22467760 C/G cg03733263 chr8:22462867 KIAA1967 1.15 20.1 0.87 7.99e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7226408 1.000 rs72883560 chr18:34372280 G/A cg06757138 chr18:34340585 FHOD3 0.27 4.59 0.38 1.08e-5 Obesity-related traits; TGCT cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg12310025 chr6:25882481 NA -0.63 -5.76 -0.46 6.4e-8 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.699 rs57574512 chr4:9960182 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs763014 0.593 rs28455838 chr16:681966 T/C cg00908189 chr16:619842 PIGQ 0.87 10.7 0.69 2.47e-19 Height; TGCT cis rs713587 0.713 rs12466350 chr2:25239969 A/G cg15423357 chr2:25149977 NA 0.58 5.91 0.47 3.05e-8 Body mass index in non-asthmatics; TGCT cis rs9297145 0.678 rs62473048 chr7:98775511 T/C cg05967295 chr7:98741636 SMURF1 0.98 12.45 0.75 1.39e-23 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg14820908 chr5:178986412 RUFY1 0.49 4.95 0.41 2.41e-6 Lung cancer; TGCT cis rs2033711 0.870 rs3764534 chr19:58929136 G/A cg13877915 chr19:58951672 ZNF132 0.89 11.13 0.71 2.22e-20 Uric acid clearance; TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg21280719 chr6:42927975 GNMT -0.38 -4.62 -0.38 9.57e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4285028 0.948 rs12488851 chr3:121687192 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs2295359 0.892 rs11209004 chr1:67613932 G/A cg12940439 chr1:67600707 NA 0.63 6.47 0.5 2.06e-9 Psoriasis; TGCT cis rs394563 0.559 rs7753269 chr6:149671360 G/A cg11245181 chr6:149772854 ZC3H12D 0.28 4.5 0.37 1.57e-5 Dupuytren's disease; TGCT cis rs7666738 0.830 rs9996098 chr4:98867740 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.501 rs17759607 chr2:99737005 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs7267979 0.873 rs6132822 chr20:25228695 C/T cg03522245 chr20:25566470 NINL 0.56 5.71 0.46 7.78e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1045529 0.524 rs34251783 chr8:8891376 T/C cg15556689 chr8:8085844 FLJ10661 -0.62 -5.24 -0.43 6.69e-7 Myopia;Myopia (pathological); TGCT cis rs8072100 0.713 rs4968318 chr17:45451894 G/A cg08085267 chr17:45401833 C17orf57 -0.51 -5.58 -0.45 1.47e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs116095464 0.558 rs6874745 chr5:264527 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs35306767 0.715 rs17293580 chr10:1034895 T/C cg18964960 chr10:1102726 WDR37 0.79 5.5 0.44 2.04e-7 Eosinophil percentage of granulocytes; TGCT cis rs9443645 0.901 rs7742431 chr6:79679577 A/G cg09184832 chr6:79620586 NA -0.49 -5.42 -0.44 2.98e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs3852122 chr4:98697400 T/C cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 0.933 rs2531726 chr17:56522533 C/T cg05425664 chr17:57184151 TRIM37 0.59 6.07 0.48 1.47e-8 Intelligence (multi-trait analysis); TGCT cis rs1478897 0.510 rs11786148 chr8:11423781 C/G cg21175976 chr8:11421337 BLK -0.36 -4.62 -0.38 9.65e-6 Systemic lupus erythematosus; TGCT cis rs7819412 0.511 rs2409797 chr8:11433780 T/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.54 -0.38 1.31e-5 Triglycerides; TGCT cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg21672276 chr3:44754072 ZNF502 0.54 6.25 0.49 5.94e-9 Depressive symptoms; TGCT cis rs1887596 0.624 rs9553860 chr13:27139814 C/T cg01312412 chr13:27282625 NA -0.26 -4.69 -0.39 6.97e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs7666738 0.830 rs6852015 chr4:99054373 C/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg20637647 chr7:64974828 NA 0.95 5.8 0.46 5.3e-8 Diabetic kidney disease; TGCT trans rs74910095 0.656 rs73761386 chr5:62932251 A/G cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7267979 0.586 rs6050445 chr20:25195394 C/T cg03522245 chr20:25566470 NINL 0.52 5.43 0.44 2.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17331151 0.573 rs79664140 chr3:52866936 A/G cg12962167 chr3:53033115 SFMBT1 0.44 4.96 0.41 2.28e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2760061 0.583 rs708121 chr1:228208257 A/G cg18477163 chr1:228402036 OBSCN 0.35 7.11 0.54 8.02e-11 Diastolic blood pressure; TGCT cis rs10493773 0.510 rs11161645 chr1:86092872 T/C cg17807903 chr1:86174739 ZNHIT6 0.4 5.06 0.41 1.45e-6 Urate levels in overweight individuals; TGCT cis rs5769765 0.671 rs138844 chr22:50184484 T/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.96 -8.65 -0.61 2.28e-14 Schizophrenia; TGCT cis rs1451375 0.756 rs11761683 chr7:50542879 C/T cg18232548 chr7:50535776 DDC -0.44 -6.46 -0.5 2.14e-9 Malaria; TGCT cis rs637571 0.512 rs660118 chr11:65735174 G/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.68 6.71 0.52 6.09e-10 Eosinophil percentage of white cells; TGCT cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs7267979 0.789 rs6083841 chr20:25384564 C/T cg16686733 chr20:25566563 NINL -0.49 -4.61 -0.38 9.76e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12497850 0.931 rs9311433 chr3:48863835 T/C cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs7191439 0.858 rs11076702 chr16:88774569 A/C cg27087555 chr16:88793112 FAM38A -0.49 -5.63 -0.45 1.15e-7 Plateletcrit; TGCT cis rs7552404 0.924 rs114752222 chr1:76180878 C/T cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs950169 1.000 rs35297609 chr15:84772896 A/G cg17173187 chr15:85201210 NMB 0.47 5.23 0.43 7.01e-7 Schizophrenia; TGCT trans rs4332037 0.707 rs73046323 chr7:1882795 G/A cg25206134 chr2:45395956 NA 0.93 7.88 0.58 1.43e-12 Bipolar disorder; TGCT trans rs2727020 0.704 rs2988340 chr11:49176057 C/T cg03929089 chr4:120376271 NA -0.61 -6.7 -0.52 6.41e-10 Coronary artery disease; TGCT cis rs1395 1.000 rs7593448 chr2:27449293 C/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.69 0.52 6.74e-10 Blood metabolite levels; TGCT cis rs8032315 0.895 rs4932370 chr15:91404705 A/G cg04510874 chr15:91427884 FES -0.49 -5.36 -0.43 3.89e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs682748 1.000 rs612378 chr5:17159362 C/T cg23987134 chr5:17158319 LOC285696 -0.23 -5.38 -0.44 3.56e-7 Hippocampal atrophy; TGCT cis rs7809950 0.817 rs62483725 chr7:107201575 G/A cg23024343 chr7:107201750 COG5 -0.47 -6.81 -0.52 3.74e-10 Coronary artery disease; TGCT cis rs1348850 0.519 rs4144275 chr2:178523368 C/T cg22681709 chr2:178499509 PDE11A -0.48 -6.09 -0.48 1.3e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9419702 0.614 rs4897816 chr10:133533646 G/A cg04492858 chr10:133558786 NA 0.55 5.71 0.46 7.96e-8 Survival in rectal cancer; TGCT cis rs1005277 0.579 rs176880 chr10:38401417 C/G cg25427524 chr10:38739819 LOC399744 0.4 8.22 0.59 2.34e-13 Extrinsic epigenetic age acceleration; TGCT cis rs35160687 1.000 rs35160687 chr2:86472114 C/T cg12542933 chr2:85804724 VAMP8 0.41 4.88 0.4 3.25e-6 Night sleep phenotypes; TGCT cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg01448562 chr3:133502909 NA -0.26 -4.74 -0.39 5.8e-6 Iron status biomarkers; TGCT cis rs12188164 0.965 rs72717435 chr5:448202 G/A cg21144161 chr5:423903 AHRR 0.25 4.69 0.39 7.08e-6 Cystic fibrosis severity; TGCT cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs7552404 0.731 rs10873788 chr1:76367857 A/C cg22875332 chr1:76189707 ACADM 0.63 6.06 0.48 1.53e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28595532 0.841 rs114363775 chr4:119765587 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs28595532 0.920 rs116023902 chr4:119725131 A/G cg21605333 chr4:119757512 SEC24D 1.72 8.96 0.63 3.99e-15 Cannabis dependence symptom count; TGCT cis rs9926296 0.605 rs1800287 chr16:89858525 C/G cg03388025 chr16:89894329 SPIRE2 0.48 8.4 0.6 8.77e-14 Vitiligo; TGCT cis rs801193 0.773 rs801207 chr7:66020590 T/C cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs6951245 1.000 rs2363286 chr7:1091625 A/G cg00738919 chr7:1100172 C7orf50 0.4 4.5 0.37 1.54e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7647973 0.826 rs9834535 chr3:49378797 A/T cg06212747 chr3:49208901 KLHDC8B 0.6 4.73 0.39 6.08e-6 Menarche (age at onset); TGCT cis rs35306767 0.903 rs17159950 chr10:875287 T/G cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs9372498 0.536 rs1319988 chr6:118782379 G/A cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg04234412 chr22:24373322 LOC391322 -0.91 -10.67 -0.69 2.98e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10540 1.000 rs61876323 chr11:462855 G/A cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs7119 0.635 rs938090 chr15:77879975 A/G cg27398640 chr15:77910606 LINGO1 0.31 6.19 0.49 8.26e-9 Type 2 diabetes; TGCT cis rs992157 1.000 rs2168704 chr2:219142492 G/A cg00012203 chr2:219082015 ARPC2 0.78 8.39 0.6 9.39e-14 Colorectal cancer; TGCT trans rs10435719 0.867 rs34583868 chr8:11791383 G/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs7666738 0.830 rs7687315 chr4:98900613 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.81 0.4 4.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg06675538 chr2:114033490 PAX8;LOC440839 0.44 4.81 0.4 4.22e-6 Lymphocyte counts; TGCT cis rs4924935 0.851 rs12936834 chr17:18807078 A/G cg26378065 chr17:18585709 ZNF286B 0.58 4.87 0.4 3.39e-6 Pancreatic cancer; TGCT cis rs2191566 1.000 rs390369 chr19:44506984 C/T cg03039196 chr19:44506973 ZNF230 -0.54 -4.75 -0.39 5.52e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs7546668 0.640 rs4661634 chr1:15808289 C/T cg17657618 chr1:15427654 KIAA1026 -0.25 -4.63 -0.38 9.03e-6 Glomerular filtration rate (creatinine); TGCT cis rs6866344 0.568 rs4626352 chr5:178096777 G/A cg10224037 chr5:178157518 ZNF354A 0.6 5.06 0.41 1.5e-6 Neutrophil percentage of white cells; TGCT trans rs1814175 0.817 rs4405313 chr11:50013636 G/A cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs10501293 0.746 rs4755184 chr11:43009790 T/C cg03447554 chr11:43094025 NA 0.43 6.1 0.48 1.26e-8 Cognitive performance; TGCT cis rs1044826 0.518 rs295488 chr3:139239323 C/T cg00490450 chr3:139108681 COPB2 0.51 4.76 0.39 5.19e-6 Obesity-related traits; TGCT cis rs2439831 0.717 rs9806227 chr15:43680115 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.14 0.59 3.58e-13 Lung cancer in ever smokers; TGCT cis rs7267979 0.933 rs2424708 chr20:25281398 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1218582 0.772 rs4240875 chr1:154885782 G/A cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs13256369 0.802 rs11781257 chr8:8559663 A/T cg17143192 chr8:8559678 CLDN23 0.53 4.82 0.4 4.03e-6 Obesity-related traits; TGCT cis rs28595532 0.841 rs116329146 chr4:119733438 G/A cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg06634786 chr22:41940651 POLR3H -0.85 -7.8 -0.57 2.16e-12 Vitiligo; TGCT cis rs2688608 0.967 rs2675663 chr10:75660270 T/G cg04320760 chr10:75533139 FUT11 -0.3 -4.57 -0.38 1.18e-5 Inflammatory bowel disease; TGCT cis rs933688 0.938 rs7708782 chr5:90718517 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.65e-14 Smoking behavior; TGCT cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg13695892 chr22:41940480 POLR3H -0.89 -8.48 -0.61 5.62e-14 Vitiligo; TGCT cis rs614226 1.000 rs7174 chr12:121017171 A/G cg01236616 chr12:121019343 POP5 1.28 13.92 0.78 4.09e-27 Type 1 diabetes nephropathy; TGCT trans rs1499614 0.522 rs13247442 chr7:66188858 T/C cg07424592 chr7:64974309 NA 1.52 8.51 0.61 4.72e-14 Gout; TGCT cis rs2980439 0.525 rs1850511 chr8:8170329 T/A cg06636001 chr8:8085503 FLJ10661 0.72 6.22 0.49 7.12e-9 Neuroticism; TGCT cis rs3820928 0.904 rs4439949 chr2:227764954 T/G cg11843606 chr2:227700838 RHBDD1 -0.53 -4.68 -0.39 7.37e-6 Pulmonary function; TGCT cis rs2235649 0.552 rs8056773 chr16:1959432 G/A cg02432467 chr16:1963432 HS3ST6 -0.31 -4.61 -0.38 9.71e-6 Blood metabolite levels; TGCT cis rs986417 1.000 rs4243618 chr14:61067022 T/C cg27398547 chr14:60952738 C14orf39 1.41 8.4 0.6 8.74e-14 Gut microbiota (bacterial taxa); TGCT cis rs3008870 1.000 rs58680688 chr1:67443751 C/G cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs644799 0.965 rs1944080 chr11:95503636 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.46 0.6 6.27e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg27535305 chr1:53392650 SCP2 0.23 4.53 0.38 1.38e-5 Monocyte count; TGCT cis rs2046867 0.818 rs11929144 chr3:72868234 T/C cg25664220 chr3:72788482 NA -0.53 -6.73 -0.52 5.6e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1568889 0.838 rs7943538 chr11:28288955 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.91 10.83 0.7 1.23e-19 Bipolar disorder; TGCT cis rs7940866 0.845 rs2324314 chr11:130834589 A/C cg12179176 chr11:130786555 SNX19 0.55 5.4 0.44 3.32e-7 Schizophrenia; TGCT cis rs8014204 0.804 rs2241274 chr14:75251331 G/A cg06637938 chr14:75390232 RPS6KL1 0.7 6.75 0.52 5.06e-10 Caffeine consumption; TGCT cis rs6582630 0.598 rs12823134 chr12:38514347 T/A cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs10791097 0.720 rs6590517 chr11:130733505 C/T cg12179176 chr11:130786555 SNX19 0.83 9.97 0.67 1.52e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9952991 0.883 rs2542147 chr18:12775851 G/T cg23598886 chr18:12777645 NA 0.62 5.78 0.46 5.63e-8 Inflammatory skin disease; TGCT cis rs727505 1.000 rs720614 chr7:124452790 T/C cg23710748 chr7:124431027 NA -0.27 -4.63 -0.38 9.07e-6 Lewy body disease; TGCT cis rs9916302 0.706 rs8078599 chr17:37518660 C/T cg07936489 chr17:37558343 FBXL20 0.88 6.28 0.49 5.31e-9 Glomerular filtration rate (creatinine); TGCT cis rs2594989 0.887 rs2447604 chr3:11574297 G/A cg26283222 chr3:11613257 VGLL4 0.23 4.66 0.39 7.97e-6 Circulating chemerin levels; TGCT cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs1371867 0.875 rs28595052 chr8:101327553 G/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs9486719 0.947 rs72932805 chr6:96902933 T/G cg18709589 chr6:96969512 KIAA0776 -0.72 -5.24 -0.43 6.58e-7 Migraine;Coronary artery disease; TGCT cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg20637647 chr7:64974828 NA 0.95 5.8 0.46 5.3e-8 Diabetic kidney disease; TGCT cis rs4523957 0.620 rs9906467 chr17:2069003 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.46 -0.37 1.8e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs5769765 0.954 rs5769762 chr22:50264042 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs28595532 0.920 rs56042726 chr4:119751777 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6815814 0.851 rs10023850 chr4:38763693 G/A cg02016764 chr4:38805732 TLR1 -0.32 -5.08 -0.42 1.35e-6 Breast cancer; TGCT cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs10927875 0.619 rs28537253 chr1:16148600 A/C cg21385522 chr1:16154831 NA -0.75 -9.3 -0.64 6.17e-16 Dilated cardiomyopathy; TGCT cis rs2153535 0.580 rs6910742 chr6:8448328 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs9916302 0.653 rs4239223 chr17:37717004 T/C cg07936489 chr17:37558343 FBXL20 -0.84 -6.16 -0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs1371867 0.817 rs1788208 chr8:101312515 T/C cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs2688482 0.512 rs3103953 chr3:195520597 G/A cg13752114 chr3:195489708 MUC4 -0.33 -4.81 -0.4 4.33e-6 Lung disease severity in cystic fibrosis; TGCT cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg18735214 chr6:43276756 CRIP3 -0.51 -4.8 -0.4 4.52e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1552244 0.572 rs6783705 chr3:10164783 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs727505 1.000 rs10228201 chr7:124449895 A/G cg23710748 chr7:124431027 NA -0.27 -4.65 -0.39 8.35e-6 Lewy body disease; TGCT cis rs9419702 0.639 rs9419624 chr10:133534822 G/A cg23460707 chr10:133558971 NA 0.42 4.84 0.4 3.8e-6 Survival in rectal cancer; TGCT cis rs6121246 0.954 rs7266148 chr20:30431070 G/T cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs8077577 0.895 rs62073615 chr17:18080329 T/A cg09161412 chr17:18057145 MYO15A -0.66 -5.36 -0.43 3.94e-7 Obesity-related traits; TGCT cis rs6740322 0.748 rs6544635 chr2:43486704 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.29 -0.49 4.92e-9 Coronary artery disease; TGCT trans rs877282 1.000 rs71491304 chr10:772982 C/T cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs9322193 0.923 rs1572229 chr6:150064977 T/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2299587 0.554 rs11778309 chr8:17747433 T/C cg04898035 chr8:17640624 MTUS1 -0.21 -4.7 -0.39 6.92e-6 Economic and political preferences; TGCT trans rs1005277 0.579 rs2472183 chr10:38392495 T/G cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT trans rs9467711 1.000 rs6903015 chr6:26322526 A/G cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs1865760 0.532 rs2794719 chr6:26088890 T/G cg17042849 chr6:26104293 HIST1H4C -0.66 -5.6 -0.45 1.33e-7 Height; TGCT cis rs4654899 0.772 rs10916892 chr1:21201325 A/G cg01072550 chr1:21505969 NA -0.47 -5.8 -0.46 5.17e-8 Superior frontal gyrus grey matter volume; TGCT cis rs11209185 0.503 rs4655573 chr1:68438778 C/T cg22082780 chr1:68452167 NA -0.31 -4.67 -0.39 7.56e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7216064 0.953 rs80135947 chr17:65836001 A/C cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1218582 0.741 rs10908447 chr1:154869742 C/T cg06221963 chr1:154839813 KCNN3 -0.79 -15.15 -0.81 5.4e-30 Prostate cancer; TGCT cis rs2980439 0.607 rs2980419 chr8:8114141 A/T cg06636001 chr8:8085503 FLJ10661 0.86 8.26 0.6 1.91e-13 Neuroticism; TGCT cis rs6569992 0.636 rs61593090 chr6:135488083 G/A cg22676075 chr6:135203613 NA 0.74 5.03 0.41 1.69e-6 Red blood cell traits; TGCT cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg00684032 chr4:1343700 KIAA1530 0.22 4.82 0.4 4.11e-6 Obesity-related traits; TGCT cis rs875971 1.000 rs778706 chr7:65860424 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs4455778 0.500 rs7783586 chr7:49057244 C/A cg26309511 chr7:48887640 NA 0.52 6.8 0.52 3.99e-10 Lung cancer in never smokers; TGCT cis rs3087591 0.708 rs2854311 chr17:29671327 C/T cg24425628 chr17:29625626 OMG;NF1 0.39 5.56 0.45 1.57e-7 Hip circumference; TGCT cis rs11190604 0.767 rs4919458 chr10:102177728 G/A cg16005271 chr10:102321736 NA -0.43 -4.45 -0.37 1.86e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6840360 0.642 rs2709825 chr4:152365563 C/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.791 rs1280275 chr6:145892402 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.873 rs7453 chr20:25207074 A/G cg03522245 chr20:25566470 NINL 0.57 6.17 0.48 8.89e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 1.000 rs6037121 chr20:25428311 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10193935 0.892 rs13413028 chr2:42394865 C/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs561341 0.714 rs111760509 chr17:30304320 A/G cg20587970 chr11:113659929 NA -1.03 -12.23 -0.74 4.82e-23 Hip circumference adjusted for BMI; TGCT cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT trans rs28735056 0.935 rs72980082 chr18:77630170 G/T cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT trans rs877282 0.898 rs11253339 chr10:759640 C/T cg22713356 chr15:30763199 NA 1.17 9.15 0.63 1.44e-15 Uric acid levels; TGCT trans rs1814175 0.647 rs61306292 chr11:49856040 G/C cg11707556 chr5:10655725 ANKRD33B -0.38 -7.3 -0.55 2.99e-11 Height; TGCT cis rs8020441 0.588 rs4534750 chr14:51188124 C/T cg04730355 chr14:51134070 SAV1 0.97 6.98 0.53 1.61e-10 Cognitive performance; TGCT cis rs5769765 0.671 rs138841 chr22:50181960 C/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.94 -8.72 -0.62 1.56e-14 Schizophrenia; TGCT cis rs10791097 0.765 rs4622274 chr11:130729486 C/T cg12179176 chr11:130786555 SNX19 0.73 8.59 0.61 3.08e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1577917 1.000 rs7771342 chr6:86631936 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs12477438 0.953 rs3851334 chr2:99794704 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.74 -5.46 -0.44 2.5e-7 Chronic sinus infection; TGCT cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg03303774 chr4:1407052 NA 0.31 4.87 0.4 3.31e-6 Obesity-related traits; TGCT cis rs67311347 0.955 rs2123999 chr3:40378738 C/T cg13683864 chr3:40499215 RPL14 -1.03 -10.79 -0.7 1.51e-19 Renal cell carcinoma; TGCT cis rs875971 0.660 rs1860470 chr7:66103694 G/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs7666738 0.710 rs7674407 chr4:98838522 A/G cg17366294 chr4:99064904 C4orf37 0.72 7.5 0.56 1.07e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2469997 0.925 rs2447173 chr8:120359513 C/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs2594989 0.831 rs7356051 chr3:11566288 A/C cg00170343 chr3:11313890 ATG7 -0.65 -4.82 -0.4 4.08e-6 Circulating chemerin levels; TGCT cis rs6570726 0.791 rs7765675 chr6:145915077 A/C cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 0.522 rs778717 chr7:65848151 G/C cg07424592 chr7:64974309 NA 1.42 8.46 0.6 6.25e-14 Diabetic kidney disease; TGCT cis rs7621025 0.500 rs1965107 chr3:136648643 T/A cg15507776 chr3:136538369 TMEM22 0.67 6.26 0.49 5.69e-9 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs34526934 0.566 rs9141 chr2:177037970 T/C cg26754761 chr2:177040938 NA -0.3 -5.57 -0.45 1.49e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs28595532 0.841 rs55823625 chr4:119780600 T/A cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs4819052 0.851 rs4819044 chr21:46660118 G/A cg06618935 chr21:46677482 NA -0.36 -5.71 -0.46 7.76e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs916888 0.773 rs538628 chr17:44787313 G/C cg16520312 chr17:43971471 MAPT;LOC100128977 -0.61 -5.07 -0.41 1.42e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2486288 0.656 rs7162022 chr15:45565253 C/T cg14582100 chr15:45693742 SPATA5L1 -0.43 -4.9 -0.4 2.91e-6 Glomerular filtration rate; TGCT cis rs453301 0.571 rs2929453 chr8:9084341 A/G cg06636001 chr8:8085503 FLJ10661 -0.54 -4.8 -0.4 4.42e-6 Joint mobility (Beighton score); TGCT cis rs12497850 0.931 rs9876848 chr3:48844059 G/A cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs7104764 0.507 rs6598054 chr11:254010 C/T cg18336825 chr11:236787 PSMD13;SIRT3 -0.67 -5.04 -0.41 1.6e-6 Menarche (age at onset); TGCT cis rs3784262 0.528 rs6493979 chr15:58338052 C/T cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.46 -0.5 2.19e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs769267 0.965 rs2074550 chr19:19387743 A/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs4851254 0.961 rs11677607 chr2:100751150 C/T cg23118464 chr2:100721844 AFF3 0.74 5.52 0.44 1.86e-7 Intelligence (multi-trait analysis); TGCT cis rs2147959 0.766 rs35724040 chr1:228782519 A/T cg22700015 chr1:228743131 NA 0.58 5.02 0.41 1.71e-6 Adult asthma; TGCT cis rs6921919 0.583 rs11755942 chr6:28369537 A/G cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9921338 0.961 rs7626 chr16:11445596 C/T cg00044050 chr16:11439710 C16orf75 -0.73 -5.69 -0.45 8.72e-8 Vein graft stenosis in coronary artery bypass grafting; TGCT trans rs2727020 0.894 rs11040333 chr11:49346332 G/A cg03929089 chr4:120376271 NA -0.64 -6.74 -0.52 5.34e-10 Coronary artery disease; TGCT cis rs7824557 0.767 rs2164273 chr8:11168499 A/G cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs514406 0.861 rs554760 chr1:53266749 G/A cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs60843830 1.000 rs10193373 chr2:281886 T/G cg00108164 chr2:264199 ACP1;SH3YL1 0.7 6.56 0.51 1.33e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs854765 0.647 rs62073573 chr17:17976354 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.72 7.42 0.55 1.6e-11 Total body bone mineral density; TGCT cis rs1218582 0.710 rs4845685 chr1:154878300 C/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs694739 0.628 rs538147 chr11:64129722 G/A cg02228329 chr11:64053129 BAD;GPR137 0.69 6.61 0.51 1.03e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs7666738 0.830 rs10001479 chr4:98918764 A/G cg05340658 chr4:99064831 C4orf37 -0.57 -6.6 -0.51 1.1e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.922 rs4338765 chr15:84916836 G/T cg12863693 chr15:85201151 NMB 0.41 4.5 0.38 1.51e-5 Schizophrenia; TGCT cis rs11586313 0.935 rs4845496 chr1:152888178 A/G cg07796016 chr1:152779584 LCE1C -0.48 -5.61 -0.45 1.27e-7 Vitamin D levels; TGCT cis rs7917772 0.536 rs3961456 chr10:104425304 A/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.82 -8.16 -0.59 3.15e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.605 rs202638 chr22:41855458 A/G cg03806693 chr22:41940476 POLR3H 1.08 11.92 0.73 2.64e-22 Vitiligo; TGCT cis rs10193935 0.901 rs59890734 chr2:42595662 G/A cg27598129 chr2:42591480 NA -0.4 -5.53 -0.44 1.83e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg04632378 chr13:21900426 NA 0.43 5.04 0.41 1.6e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT trans rs4332037 0.539 rs56305291 chr7:2048706 A/G cg25206134 chr2:45395956 NA 0.96 7.24 0.55 4.07e-11 Bipolar disorder; TGCT cis rs7178572 0.568 rs4886862 chr15:77652368 T/C cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs9430161 0.579 rs7542354 chr1:11040385 G/A cg27631724 chr1:11040367 C1orf127 0.55 6.58 0.51 1.2e-9 Ewing sarcoma; TGCT cis rs7169223 0.615 rs8038189 chr15:79099026 G/C cg21242079 chr15:79101063 ADAMTS7 0.36 5.74 0.46 6.73e-8 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT trans rs916888 0.647 rs199449 chr17:44808902 G/A cg10053473 chr17:62856997 LRRC37A3 -0.42 -7.04 -0.53 1.16e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10540 0.908 rs1044707 chr11:491334 G/T cg03934478 chr11:495069 RNH1 -0.34 -5.91 -0.47 3.07e-8 Body mass index; TGCT cis rs3849046 0.781 rs4835691 chr5:137938573 G/T cg24064279 chr5:137839461 NA -0.28 -4.47 -0.37 1.77e-5 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs8031584 0.752 rs34722914 chr15:31191991 G/A cg08109568 chr15:31115862 NA -0.35 -4.79 -0.4 4.66e-6 Huntington's disease progression; TGCT cis rs7666738 0.515 rs13118898 chr4:98792893 T/A cg18180107 chr4:99064573 C4orf37 0.52 4.58 0.38 1.13e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.877 rs10070390 chr5:93452345 G/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs2241685 0.850 rs7565890 chr2:1942959 G/A cg21862353 chr2:1801628 MYT1L -0.52 -4.77 -0.39 5.05e-6 Attention deficit hyperactivity disorder; TGCT cis rs3617 0.652 rs60332615 chr3:52867595 C/A cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs79349575 0.715 rs1058018 chr17:47000251 C/T cg07967210 chr17:47022446 SNF8 0.37 5.07 0.41 1.43e-6 Type 2 diabetes; TGCT cis rs250677 0.641 rs2915807 chr5:148450950 A/G cg23229984 chr5:148520753 ABLIM3 0.23 5.1 0.42 1.25e-6 Breast cancer; TGCT cis rs9915657 0.933 rs17246133 chr17:70140485 A/G cg06234051 chr17:70120541 SOX9 -0.24 -4.7 -0.39 6.93e-6 Thyroid hormone levels; TGCT cis rs2456568 0.900 rs2000960 chr11:93682348 C/T cg16099599 chr11:93583650 C11orf90 -0.39 -4.69 -0.39 7.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2640806 0.505 rs7012725 chr8:97361834 C/T cg04026948 chr8:97953330 PGCP -0.25 -4.5 -0.37 1.55e-5 Obesity-related traits; TGCT cis rs4372836 0.504 rs7601413 chr2:29032238 C/T cg09522027 chr2:28974177 PPP1CB -0.56 -5.58 -0.45 1.42e-7 Body mass index; TGCT cis rs6500602 0.701 rs8129 chr16:4562351 A/G cg08645402 chr16:4508243 NA 0.2 5.04 0.41 1.58e-6 Schizophrenia; TGCT cis rs2535633 0.588 rs2564930 chr3:53017307 T/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.49 -4.48 -0.37 1.66e-5 Body mass index; TGCT cis rs514406 0.505 rs387436 chr1:53179376 C/T cg22166914 chr1:53195759 ZYG11B -0.45 -8.14 -0.59 3.47e-13 Monocyte count; TGCT cis rs11711311 1.000 rs7633832 chr3:113472292 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs7267979 1.000 rs1888998 chr20:25291826 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9473924 0.580 rs66462826 chr6:50814877 C/A cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs849898 1 rs849898 chr1:228153917 A/G cg02753203 chr1:228287806 NA -0.4 -8.18 -0.59 2.91e-13 Parkinson's disease; TGCT cis rs35306767 0.855 rs61830900 chr10:871481 C/G cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs478304 0.593 rs4645927 chr11:65482827 C/T cg12758867 chr11:65354231 EHBP1L1 0.26 4.48 0.37 1.67e-5 Acne (severe); TGCT cis rs514406 0.505 rs416968 chr1:53183513 A/G cg08859206 chr1:53392774 SCP2 -0.33 -4.74 -0.39 5.64e-6 Monocyte count; TGCT cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg04025307 chr7:1156635 C7orf50 0.23 5.38 0.44 3.52e-7 Longevity;Endometriosis; TGCT cis rs4901869 0.966 rs4901868 chr14:59333792 C/T cg02291164 chr14:59296302 NA -0.25 -4.94 -0.41 2.51e-6 Panic disorder; TGCT cis rs9393692 0.905 rs9366649 chr6:26329103 A/T cg05868516 chr6:26286170 HIST1H4H -0.55 -5.23 -0.43 6.92e-7 Educational attainment; TGCT cis rs7959452 0.718 rs10878963 chr12:69717166 T/G cg14784868 chr12:69753453 YEATS4 0.58 5.59 0.45 1.35e-7 Blood protein levels; TGCT cis rs2282802 0.677 rs9686454 chr5:139627813 T/C cg01081189 chr5:139537190 NA 0.29 5.22 0.42 7.24e-7 Intelligence (multi-trait analysis); TGCT cis rs6671200 0.790 rs259357 chr1:95711478 G/T cg20701556 chr1:95698924 RWDD3 -0.67 -5.63 -0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs79387448 0.638 rs74731686 chr2:103043981 G/A cg09003973 chr2:102972529 NA 1.27 9.82 0.66 3.37e-17 Gut microbiota (bacterial taxa); TGCT cis rs4788570 0.615 rs4788550 chr16:71720523 C/T cg06353428 chr16:71660113 MARVELD3 1.56 12.54 0.75 8.54e-24 Intelligence (multi-trait analysis); TGCT cis rs763121 0.853 rs5750627 chr22:38982321 A/G cg06022373 chr22:39101656 GTPBP1 0.82 8.37 0.6 1.05e-13 Menopause (age at onset); TGCT cis rs2120019 0.938 rs8030089 chr15:75290377 C/T cg09165964 chr15:75287851 SCAMP5 -1.14 -9.98 -0.67 1.43e-17 Blood trace element (Zn levels); TGCT cis rs116095464 0.558 rs11959126 chr5:283880 T/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs9611565 0.568 rs2413656 chr22:42129357 G/T cg17554472 chr22:41940697 POLR3H 0.44 4.62 0.38 9.38e-6 Vitiligo; TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg16325326 chr1:53192061 ZYG11B -0.64 -7.19 -0.54 5.26e-11 Monocyte count; TGCT cis rs17376456 0.809 rs13177800 chr5:93307350 T/C cg25358565 chr5:93447407 FAM172A 0.99 8.37 0.6 1.02e-13 Diabetic retinopathy; TGCT cis rs9393692 0.905 rs4412192 chr6:26290377 A/G cg13736514 chr6:26305472 NA 0.37 5.42 0.44 3.01e-7 Educational attainment; TGCT cis rs9807989 0.507 rs2287033 chr2:103011237 C/T cg03938978 chr2:103052716 IL18RAP -0.27 -5.54 -0.45 1.71e-7 Asthma; TGCT cis rs9914544 1.000 rs59682951 chr17:18800766 G/T cg26306683 chr17:18585705 ZNF286B 0.56 4.97 0.41 2.18e-6 Educational attainment (years of education); TGCT cis rs6860806 0.661 rs4705927 chr5:131578608 C/G cg24060327 chr5:131705240 SLC22A5 -0.53 -5.42 -0.44 2.97e-7 Breast cancer; TGCT cis rs6860806 0.661 rs4705929 chr5:131584178 G/T cg24060327 chr5:131705240 SLC22A5 -0.56 -5.6 -0.45 1.34e-7 Breast cancer; TGCT cis rs981844 0.712 rs4538465 chr4:154746763 T/C cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs875971 0.895 rs3857684 chr7:65938158 G/C cg11764359 chr7:65958608 NA 0.59 5.29 0.43 5.45e-7 Aortic root size; TGCT cis rs9814567 0.896 rs4435682 chr3:134344182 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.85 7.73 0.57 3.19e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6061231 0.544 rs2427314 chr20:60973666 C/T cg22633769 chr20:60982531 CABLES2 0.59 4.85 0.4 3.63e-6 Colorectal cancer; TGCT cis rs12291225 0.645 rs3763950 chr11:14278049 T/A cg19336497 chr11:14380999 RRAS2 -0.39 -6.09 -0.48 1.31e-8 Sense of smell; TGCT cis rs2204008 0.606 rs1581358 chr12:38391582 G/T cg26384229 chr12:38710491 ALG10B 0.84 7.3 0.55 2.97e-11 Bladder cancer; TGCT cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg10047753 chr17:41438598 NA 0.95 9.0 0.63 3.2e-15 Menopause (age at onset); TGCT cis rs42648 0.738 rs13247172 chr7:89889204 A/C cg25739043 chr7:89950458 NA -0.53 -4.69 -0.39 7.14e-6 Homocysteine levels; TGCT cis rs2361718 0.522 rs11867921 chr17:78121170 G/T cg09238746 chr17:78121135 EIF4A3 -1.15 -11.72 -0.73 8.12e-22 Yeast infection; TGCT cis rs10746514 0.833 rs1888601 chr1:232266922 C/T cg09506761 chr1:232265262 NA -0.49 -5.01 -0.41 1.79e-6 Response to statin therapy; TGCT cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs147858478 1 rs147858478 chr5:131682785 CCTGAGTT/C cg24060327 chr5:131705240 SLC22A5 -0.56 -6.26 -0.49 5.61e-9 High light scatter reticulocyte percentage of red cells; TGCT cis rs12472274 0.941 rs36066920 chr2:239074480 T/G cg17459225 chr2:239074497 NA 0.31 4.57 0.38 1.15e-5 Phospholipid levels (plasma); TGCT cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg08392591 chr16:89556376 ANKRD11 0.59 5.48 0.44 2.32e-7 Multiple myeloma (IgH translocation); TGCT cis rs60843830 1.000 rs56167434 chr2:282137 G/C cg00108164 chr2:264199 ACP1;SH3YL1 0.7 6.41 0.5 2.81e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7582180 0.629 rs4851298 chr2:100949827 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7769051 1.000 rs9493454 chr6:133144629 G/T cg22852734 chr6:133119734 C6orf192 -1.3 -7.33 -0.55 2.6e-11 Type 2 diabetes nephropathy; TGCT cis rs4819052 0.851 rs2838826 chr21:46655785 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 5.94 0.47 2.67e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9611519 0.929 rs12484477 chr22:41429084 G/A cg03806693 chr22:41940476 POLR3H -0.7 -6.22 -0.49 6.88e-9 Neuroticism; TGCT cis rs9383153 0.793 rs2016498 chr6:16344914 C/T cg23850913 chr6:15505452 JARID2 0.87 5.22 0.42 7.32e-7 Gambling; TGCT cis rs7103648 0.864 rs10769264 chr11:47423340 C/T cg20307385 chr11:47447363 PSMC3 1.0 12.09 0.74 1.06e-22 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs7236492 0.688 rs9709477 chr18:77202786 C/A cg15644404 chr18:77186268 NFATC1 -0.35 -4.64 -0.38 8.67e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7954584 0.531 rs1154514 chr12:122374888 C/T cg13699009 chr12:122356056 WDR66 0.29 5.7 0.46 8.3e-8 Mean corpuscular volume; TGCT cis rs4699052 0.739 rs11936824 chr4:104238003 T/G cg16532752 chr4:104119610 CENPE -0.54 -5.48 -0.44 2.23e-7 Testicular germ cell tumor; TGCT cis rs8072100 0.790 rs11079783 chr17:45686016 C/T cg08085267 chr17:45401833 C17orf57 0.46 5.01 0.41 1.82e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs513349 0.964 rs210139 chr6:33543409 A/C cg24505687 chr6:33548425 BAK1 0.51 6.46 0.5 2.2e-9 Platelet count; TGCT cis rs597539 0.690 rs608810 chr11:68624118 G/C cg04772025 chr11:68637568 NA 0.62 6.54 0.51 1.42e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6121246 0.529 rs56153385 chr20:30187609 C/T cg13852791 chr20:30311386 BCL2L1 0.69 4.65 0.39 8.44e-6 Mean corpuscular hemoglobin; TGCT cis rs2576037 0.583 rs512699 chr18:44374681 C/T cg23302884 chr18:44338147 ST8SIA5 0.4 4.7 0.39 6.77e-6 Personality dimensions; TGCT cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs11122272 0.735 rs2486737 chr1:231520523 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs11209002 0.567 rs2815385 chr1:67542083 A/G cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs765787 0.530 rs11636395 chr15:45535684 G/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.59 -0.45 1.37e-7 Uric acid levels; TGCT cis rs9467711 0.606 rs66823108 chr6:26377939 G/A cg16898833 chr6:26189333 HIST1H4D 1.1 5.3 0.43 5.01e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs922182 0.613 rs8028927 chr15:64232281 A/G cg02919090 chr15:64263738 DAPK2 -0.33 -6.14 -0.48 1.05e-8 Blood protein levels; TGCT cis rs4654899 0.931 rs1152998 chr1:21124290 C/T cg01072550 chr1:21505969 NA -0.48 -7.65 -0.57 4.72e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7267979 0.833 rs6138556 chr20:25243310 C/T cg03522245 chr20:25566470 NINL 0.58 6.25 0.49 6.16e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1062177 1.000 rs2347596 chr5:151179199 T/C cg12924095 chr5:151150029 G3BP1 0.35 5.08 0.42 1.34e-6 Preschool internalizing problems; TGCT cis rs62244186 0.659 rs4431151 chr3:44510906 G/C cg02073558 chr3:44770973 ZNF501 0.61 5.79 0.46 5.39e-8 Depressive symptoms; TGCT cis rs9916302 0.851 rs6503518 chr17:37660469 A/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs3617 0.572 rs2256332 chr3:52855865 A/G cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.85 0.4 3.62e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7598759 0.527 rs12987949 chr2:232367511 A/G cg19187155 chr2:232395269 NMUR1 0.52 6.18 0.49 8.55e-9 Noise-induced hearing loss; TGCT cis rs4824093 0.541 rs8142132 chr22:50211294 C/T cg20569369 chr22:51173646 NA 0.34 5.34 0.43 4.22e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs55962025 0.855 rs4498089 chr4:3080199 A/G cg06533319 chr4:3265114 C4orf44 0.23 4.61 0.38 9.86e-6 Parental longevity (mother's age at death); TGCT cis rs36051895 0.559 rs1590268 chr9:5209433 T/A cg02405213 chr9:5042618 JAK2 -0.67 -8.47 -0.61 5.81e-14 Pediatric autoimmune diseases; TGCT trans rs57221529 0.766 rs4245972 chr5:578572 A/G cg25482853 chr8:67687455 SGK3 1.16 10.5 0.69 7.91e-19 Lung disease severity in cystic fibrosis; TGCT cis rs6570726 0.935 rs454370 chr6:145846729 T/G cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.758 rs7789093 chr7:1002981 T/C cg07930192 chr7:1003750 NA 0.3 4.72 0.39 6.33e-6 Longevity;Endometriosis; TGCT cis rs7666738 0.830 rs7659006 chr4:98934529 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4824093 0.610 rs73441787 chr22:50269646 A/G cg14114931 chr22:50943910 LMF2 0.37 4.58 0.38 1.11e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7666738 0.791 rs1896155 chr4:99020948 C/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.659 rs12339666 chr9:5063296 A/C cg02405213 chr9:5042618 JAK2 0.79 11.45 0.72 3.74e-21 Pediatric autoimmune diseases; TGCT cis rs644799 0.862 rs1150361 chr11:95633805 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.73 7.37 0.55 2.05e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9911578 1.000 rs9915935 chr17:56843048 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs4746818 1.000 rs7899844 chr10:70949694 A/G cg04149295 chr10:70884716 VPS26A 0.78 5.32 0.43 4.7e-7 Left atrial antero-posterior diameter; TGCT cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs72717009 0.825 rs9427399 chr1:161476533 T/C cg23840854 chr1:161414152 NA -0.98 -5.86 -0.47 3.95e-8 Rheumatoid arthritis; TGCT cis rs4937076 1.000 rs4937076 chr11:125826702 G/A cg17967973 chr11:126139042 FOXRED1;SRPR -0.4 -4.66 -0.39 8.05e-6 Primary tooth development (time to first tooth eruption); TGCT cis rs4076764 0.846 rs7525724 chr1:163426372 G/A cg24596788 chr1:163392923 NA -0.17 -4.88 -0.4 3.17e-6 Motion sickness; TGCT cis rs28735056 1.000 rs28865701 chr18:77620911 A/G cg20368463 chr18:77673604 PQLC1 -0.45 -5.66 -0.45 9.83e-8 Schizophrenia; TGCT cis rs7980687 0.678 rs7132277 chr12:123593382 C/T cg00376283 chr12:123451042 ABCB9 -0.69 -4.73 -0.39 5.98e-6 Height;Educational attainment;Head circumference (infant); TGCT cis rs9911578 0.867 rs4793941 chr17:56472366 G/A cg12560992 chr17:57184187 TRIM37 -0.76 -8.94 -0.63 4.6e-15 Intelligence (multi-trait analysis); TGCT cis rs6163 0.588 rs3818708 chr10:104503584 C/T cg05855489 chr10:104503620 C10orf26 0.98 12.41 0.74 1.75e-23 Waist circumference;Hip circumference; TGCT cis rs4803468 1.000 rs10417311 chr19:41902038 G/A cg09537434 chr19:41945824 ATP5SL -0.89 -10.04 -0.67 9.93e-18 Height; TGCT cis rs796364 1.000 rs281774 chr2:200814572 C/T cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs2841277 0.708 rs4465542 chr14:105407798 A/G cg19901468 chr14:105411992 AHNAK2 -0.27 -6.17 -0.48 9.09e-9 Rheumatoid arthritis; TGCT cis rs9611519 0.780 rs9611546 chr22:41698542 C/G cg03806693 chr22:41940476 POLR3H -0.84 -8.39 -0.6 9.17e-14 Neuroticism; TGCT cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg11644478 chr21:40555479 PSMG1 0.61 5.71 0.46 7.78e-8 Cognitive function; TGCT cis rs7226408 0.857 rs57901563 chr18:34453207 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs453301 0.686 rs4840389 chr8:8884503 G/C cg15556689 chr8:8085844 FLJ10661 -0.66 -5.4 -0.44 3.27e-7 Joint mobility (Beighton score); TGCT cis rs916888 0.821 rs199507 chr17:44858855 A/G cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4253772 0.530 rs28528366 chr22:46680696 G/A cg24881330 chr22:46731750 TRMU 1.0 4.88 0.4 3.25e-6 LDL cholesterol;Cholesterol, total; TGCT trans rs8073060 0.545 rs3859282 chr17:34006111 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.28 0.49 5.32e-9 Schizophrenia; TGCT cis rs7098414 0.531 rs3844126 chr10:82019997 T/G cg01528321 chr10:82214614 TSPAN14 0.63 5.66 0.45 9.73e-8 Post bronchodilator FEV1; TGCT cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg11003573 chr3:44754125 ZNF502 -0.45 -5.08 -0.42 1.32e-6 Depressive symptoms; TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs9326248 1.000 rs7107152 chr11:117056080 C/T cg16524733 chr11:117070046 TAGLN -0.33 -5.2 -0.42 7.82e-7 Blood protein levels; TGCT cis rs3008870 1.000 rs12132068 chr1:67451924 G/T cg03991309 chr1:68237761 GNG12 -0.27 -4.55 -0.38 1.25e-5 Lymphocyte percentage of white cells; TGCT cis rs6582630 0.593 rs11182590 chr12:38574274 A/T cg26384229 chr12:38710491 ALG10B 0.61 5.74 0.46 6.87e-8 Drug-induced liver injury (flucloxacillin); TGCT trans rs2727020 0.523 rs4115783 chr11:49556026 G/A cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Coronary artery disease; TGCT cis rs9926296 0.533 rs12102297 chr16:89812762 C/A cg27121462 chr16:89883253 FANCA 0.82 8.95 0.63 4.3e-15 Vitiligo; TGCT cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs2276314 0.857 rs4799409 chr18:33592602 C/T cg19628046 chr18:33552617 C18orf21 0.51 4.46 0.37 1.79e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs601339 0.536 rs575171 chr12:123194635 C/T cg11919336 chr12:123188078 GPR109A 0.65 7.82 0.57 1.96e-12 Adiponectin levels; TGCT trans rs877282 0.898 rs11253349 chr10:765897 C/G cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs56104184 0.775 rs17272700 chr19:49391770 G/A cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9467773 0.901 rs1407045 chr6:26476155 A/G cg26531700 chr6:26746687 NA 0.57 5.51 0.44 1.98e-7 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.628 rs11777746 chr8:11204755 T/C cg21775007 chr8:11205619 TDH 0.72 7.0 0.53 1.45e-10 Retinal vascular caliber; TGCT cis rs12983728 0.536 rs34380569 chr19:58648528 A/G cg07378217 chr19:58662286 ZNF329 -0.63 -4.69 -0.39 7.1e-6 Cholesterol, total; TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.73 -7.31 -0.55 2.95e-11 Prudent dietary pattern; TGCT cis rs11190604 1.000 rs2495742 chr10:102331364 C/T cg23241863 chr10:102295624 HIF1AN 0.66 4.87 0.4 3.37e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7590720 0.788 rs4674050 chr2:216907322 G/T cg12620499 chr2:216877984 MREG 0.91 10.36 0.68 1.66e-18 Alcohol dependence; TGCT cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.79 -0.46 5.54e-8 Coronary artery disease; TGCT cis rs2354432 0.607 rs10453880 chr1:146693689 T/C cg25205988 chr1:146714368 CHD1L 1.33 6.35 0.5 3.68e-9 Mitochondrial DNA levels; TGCT cis rs7809950 0.768 rs62482493 chr7:106951579 T/C cg23024343 chr7:107201750 COG5 -0.41 -5.58 -0.45 1.43e-7 Coronary artery disease; TGCT cis rs6546537 0.714 rs17036759 chr2:69767029 C/T cg10773587 chr2:69614142 GFPT1 -0.88 -9.03 -0.63 2.79e-15 Serum thyroid-stimulating hormone levels; TGCT cis rs7192750 0.562 rs9921412 chr16:71988106 C/T cg06353428 chr16:71660113 MARVELD3 0.74 6.6 0.51 1.09e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7772486 0.754 rs702318 chr6:146005873 G/T cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs208520 0.874 rs208469 chr6:66915891 T/C cg07460842 chr6:66804631 NA -0.9 -9.16 -0.64 1.34e-15 Exhaled nitric oxide output; TGCT cis rs477895 1.000 rs41294396 chr11:64078581 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.19 0.42 8.41e-7 Mean platelet volume; TGCT cis rs66573146 1.000 rs73202122 chr4:7005594 G/A cg01220768 chr4:7056774 TADA2B 0.41 4.88 0.4 3.16e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4665809 1.000 rs6729757 chr2:26285102 A/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs7267979 0.966 rs2261785 chr20:25262403 C/T cg16686733 chr20:25566563 NINL 0.61 6.1 0.48 1.23e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs72781680 0.821 rs11894756 chr2:24170214 A/G cg08917208 chr2:24149416 ATAD2B -0.74 -4.66 -0.39 7.9e-6 Lymphocyte counts; TGCT cis rs909002 0.925 rs10798882 chr1:32108547 C/G cg11573219 chr1:32083031 HCRTR1 0.48 6.2 0.49 7.79e-9 Intelligence (multi-trait analysis); TGCT cis rs7927592 0.513 rs607887 chr11:68196961 C/T cg16797656 chr11:68205561 LRP5 0.28 5.13 0.42 1.1e-6 Total body bone mineral density; TGCT cis rs910316 1.000 rs8017642 chr14:75590822 G/A cg08847533 chr14:75593920 NEK9 0.95 10.55 0.69 5.83e-19 Height; TGCT cis rs6912958 0.559 rs446851 chr6:88043640 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.73 7.68 0.57 4.16e-12 Monocyte percentage of white cells; TGCT cis rs7552404 0.731 rs10873808 chr1:76406767 T/C cg22875332 chr1:76189707 ACADM 0.68 6.54 0.51 1.43e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2075371 0.829 rs11770764 chr7:134003308 T/C cg11752832 chr7:134001865 SLC35B4 0.74 6.69 0.51 6.91e-10 Mean platelet volume; TGCT cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg20607798 chr8:58055168 NA 0.45 4.62 0.38 9.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs2034088 0.507 rs11650424 chr17:435896 C/T cg01214346 chr17:406501 NA -0.39 -5.0 -0.41 1.88e-6 Hip circumference adjusted for BMI; TGCT cis rs67311347 0.568 rs57287242 chr3:40335538 T/C cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs9300255 0.510 rs1790086 chr12:123672518 A/G cg00376283 chr12:123451042 ABCB9 0.73 5.69 0.46 8.5e-8 Neutrophil percentage of white cells; TGCT cis rs1552244 0.510 rs13075308 chr3:10034925 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs3087591 1.000 rs6505235 chr17:29688603 C/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.22 -0.54 4.48e-11 Hip circumference; TGCT cis rs9911578 0.967 rs2429369 chr17:56501420 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.26 0.64 7.61e-16 Intelligence (multi-trait analysis); TGCT cis rs4268898 0.760 rs11125535 chr2:24528114 T/C cg02683114 chr2:24398427 C2orf84 0.2 4.95 0.41 2.42e-6 Asthma; TGCT cis rs1008375 1.000 rs1008374 chr4:17683219 G/A cg16339924 chr4:17578868 LAP3 0.52 4.56 0.38 1.19e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6570726 0.846 rs6914304 chr6:145921017 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.5 -0.37 1.53e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs17384381 1.000 rs12138852 chr1:85878208 C/T cg16011679 chr1:85725395 C1orf52 0.8 6.44 0.5 2.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg11644478 chr21:40555479 PSMG1 -0.54 -5.12 -0.42 1.15e-6 Menarche (age at onset); TGCT cis rs4824093 0.535 rs9627797 chr22:50317569 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.17 -4.53 -0.38 1.34e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs13108904 0.518 rs4974603 chr4:1343168 C/T cg13395646 chr4:1353034 KIAA1530 -0.58 -7.81 -0.57 2.08e-12 Obesity-related traits; TGCT cis rs17376456 0.825 rs28534784 chr5:93063332 C/A cg09848695 chr5:92956644 FAM172A;MIR2277 0.68 5.05 0.41 1.51e-6 Diabetic retinopathy; TGCT cis rs7264396 0.690 rs2425165 chr20:34438059 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs10088262 0.629 rs7828192 chr8:124804669 C/T cg20713898 chr8:124780851 FAM91A1 -0.84 -7.19 -0.54 5.3e-11 Pancreatic cancer; TGCT cis rs68170813 0.617 rs76923959 chr7:107182915 T/C cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs2380220 0.541 rs72928277 chr6:96079745 G/T cg04719120 chr6:96025338 MANEA -0.74 -5.48 -0.44 2.25e-7 Behavioural disinhibition (generation interaction); TGCT cis rs2242116 0.727 rs10865943 chr3:46969970 T/C cg27129171 chr3:47204927 SETD2 0.66 6.63 0.51 9.04e-10 Birth weight; TGCT cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg02353165 chr6:42928485 GNMT 0.97 9.95 0.67 1.66e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9916302 0.904 rs9905432 chr17:37555918 C/A cg07936489 chr17:37558343 FBXL20 0.65 4.98 0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs792975 0.666 rs710109 chr5:172272571 G/A cg15947959 chr5:172261155 ERGIC1 -0.62 -4.44 -0.37 1.95e-5 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel); TGCT cis rs28595532 0.920 rs55794497 chr4:119764664 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7296418 0.738 rs1568428 chr12:123738876 A/G cg00376283 chr12:123451042 ABCB9 -0.71 -6.89 -0.53 2.51e-10 Platelet count; TGCT cis rs3020736 0.500 rs8138678 chr22:42516229 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs231513 0.636 rs34239920 chr17:42013076 G/T cg26893861 chr17:41843967 DUSP3 0.76 4.64 0.38 8.65e-6 Cognitive function; TGCT cis rs7781977 0.960 rs4917017 chr7:50335232 A/G cg14216940 chr7:50343131 IKZF1 -0.38 -4.48 -0.37 1.66e-5 IgG glycosylation; TGCT cis rs59107033 0.509 rs60496964 chr3:123102795 T/C cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Lymphocyte counts; TGCT cis rs60843830 1.000 rs3791223 chr2:222336 T/C cg25945732 chr2:264204 ACP1;SH3YL1 0.77 7.44 0.56 1.47e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg19729930 chr2:74357872 NA 0.58 7.04 0.53 1.14e-10 Gestational age at birth (maternal effect); TGCT trans rs877282 0.898 rs10904547 chr10:766283 C/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs10540 0.915 rs35389167 chr11:460765 A/G cg03934478 chr11:495069 RNH1 0.35 5.88 0.47 3.51e-8 Body mass index; TGCT cis rs36051895 0.632 rs10974969 chr9:5125336 G/A cg02405213 chr9:5042618 JAK2 -0.71 -9.55 -0.65 1.57e-16 Pediatric autoimmune diseases; TGCT cis rs548987 0.529 rs9467618 chr6:25824809 C/T cg03264133 chr6:25882463 NA -0.54 -4.44 -0.37 1.99e-5 Homocysteine levels; TGCT cis rs7208859 0.623 rs12103440 chr17:29086657 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg04025307 chr7:1156635 C7orf50 0.23 5.23 0.43 6.91e-7 Longevity;Endometriosis; TGCT cis rs12479064 0.671 rs4851207 chr2:100105775 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -6.02 -0.48 1.85e-8 Chronic sinus infection; TGCT cis rs4700695 0.614 rs2561241 chr5:65206565 C/T cg21114390 chr5:65439923 SFRS12 0.77 5.42 0.44 3e-7 Facial morphology (factor 19); TGCT cis rs514406 0.861 rs554760 chr1:53266749 G/A cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs11098499 1.000 rs28374891 chr4:120183550 G/A cg24670566 chr4:120433619 PDE5A 0.23 4.58 0.38 1.1e-5 Corneal astigmatism; TGCT cis rs9300255 0.512 rs2851436 chr12:123667354 G/T cg00376283 chr12:123451042 ABCB9 0.73 5.69 0.46 8.5e-8 Neutrophil percentage of white cells; TGCT cis rs9868809 0.772 rs9812977 chr3:48720303 G/A cg15315015 chr3:49131774 QRICH1 0.95 4.54 0.38 1.31e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs875971 0.838 rs2173570 chr7:65762963 T/A cg11764359 chr7:65958608 NA -0.61 -5.36 -0.43 3.96e-7 Aortic root size; TGCT cis rs1981331 0.867 rs76188425 chr21:48002207 C/T cg23283320 chr21:48055893 PRMT2 1.29 6.09 0.48 1.31e-8 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg10295955 chr4:187884368 NA 0.93 13.29 0.77 1.35e-25 Lobe attachment (rater-scored or self-reported); TGCT cis rs344364 0.511 rs2906912 chr16:1953151 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.46 -5.31 -0.43 4.97e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7633770 0.769 rs2385858 chr3:46660436 T/C cg11219411 chr3:46661640 NA 0.36 5.27 0.43 5.86e-7 Coronary artery disease; TGCT cis rs295140 1.000 rs12618057 chr2:201171355 T/C cg04283868 chr2:201171347 SPATS2L 0.63 6.39 0.5 3.03e-9 QT interval; TGCT cis rs6952808 0.630 rs1860832 chr7:2161849 G/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.24 -0.49 6.33e-9 Bipolar disorder and schizophrenia; TGCT cis rs9393692 0.905 rs7769028 chr6:26267568 C/T cg05868516 chr6:26286170 HIST1H4H 0.63 5.94 0.47 2.72e-8 Educational attainment; TGCT cis rs7086627 0.515 rs11202959 chr10:82209672 A/G cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs6840360 0.571 rs4696110 chr4:152671325 G/A cg22705602 chr4:152727874 NA -0.34 -5.83 -0.46 4.43e-8 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.671 rs2591970 chr5:56232595 T/C cg20203395 chr5:56204925 C5orf35 0.53 4.92 0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs3749237 0.964 rs62260719 chr3:49852419 G/A cg10152585 chr3:50297680 NA 0.53 5.02 0.41 1.75e-6 Resting heart rate; TGCT cis rs17122693 0.786 rs72679588 chr14:51092687 A/C cg04730355 chr14:51134070 SAV1 1.24 8.74 0.62 1.38e-14 Cognitive performance; TGCT cis rs4788570 0.545 rs8044144 chr16:71783121 T/C cg06353428 chr16:71660113 MARVELD3 1.56 12.67 0.75 4.05e-24 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg21724239 chr8:58056113 NA -0.39 -4.59 -0.38 1.07e-5 Developmental language disorder (linguistic errors); TGCT cis rs7605378 1.000 rs769958 chr2:200695901 G/A cg23649088 chr2:200775458 C2orf69 0.35 5.73 0.46 7.15e-8 Osteoporosis; TGCT trans rs1005277 0.579 rs2505198 chr10:38393183 A/C cg17830980 chr10:43048298 ZNF37B -0.84 -10.94 -0.7 6.62e-20 Extrinsic epigenetic age acceleration; TGCT cis rs4730250 0.707 rs257378 chr7:106801395 C/G cg02696742 chr7:106810147 HBP1 -0.71 -5.89 -0.47 3.42e-8 Osteoarthritis; TGCT cis rs7914558 1.000 rs4917994 chr10:104811699 C/T cg04362960 chr10:104952993 NT5C2 0.61 5.46 0.44 2.44e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2295359 0.892 rs12401432 chr1:67656931 C/G cg08029281 chr1:67600428 NA 0.4 4.72 0.39 6.15e-6 Psoriasis; TGCT cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg10047753 chr17:41438598 NA 0.95 8.81 0.62 9.26e-15 Menopause (age at onset); TGCT cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg15659132 chr6:26577336 NA 0.84 10.89 0.7 8.44e-20 Intelligence (multi-trait analysis); TGCT cis rs709400 0.663 rs17679475 chr14:103916958 A/G cg12935359 chr14:103987150 CKB -0.35 -5.28 -0.43 5.51e-7 Body mass index; TGCT cis rs7666738 0.830 rs10009206 chr4:99056900 A/C cg18180107 chr4:99064573 C4orf37 -0.58 -5.37 -0.43 3.77e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs727563 0.635 rs713988 chr22:42159072 A/G cg06634786 chr22:41940651 POLR3H 0.86 8.01 0.58 7.16e-13 Crohn's disease;Inflammatory bowel disease; TGCT trans rs208520 0.560 rs2351880 chr6:66863707 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs9549260 0.755 rs17061450 chr13:41183716 G/A cg21288729 chr13:41239152 FOXO1 1.02 10.32 0.68 2.17e-18 Red blood cell count; TGCT cis rs986417 0.901 rs7150630 chr14:61019458 T/A cg27398547 chr14:60952738 C14orf39 1.49 10.43 0.68 1.12e-18 Gut microbiota (bacterial taxa); TGCT cis rs7666738 0.791 rs2081621 chr4:98926753 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1538970 0.962 rs7544178 chr1:45819069 C/T cg05343316 chr1:45956843 TESK2 0.64 5.1 0.42 1.26e-6 Platelet count; TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg24503407 chr1:205819492 PM20D1 -0.51 -7.05 -0.53 1.11e-10 Monocyte percentage of white cells; TGCT cis rs2180341 0.597 rs11154397 chr6:127646649 G/C cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs3749237 0.576 rs4241406 chr3:49600426 C/T cg03060546 chr3:49711283 APEH 0.78 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs12142240 0.698 rs72677599 chr1:46834251 G/A cg00530320 chr1:46809349 NSUN4 0.29 6.03 0.48 1.71e-8 Menopause (age at onset); TGCT cis rs4478858 0.735 rs4949382 chr1:31776731 A/G cg07478791 chr1:31886160 SERINC2 -0.48 -4.61 -0.38 1e-5 Alcohol dependence; TGCT cis rs7523273 0.606 rs2488255 chr1:207941741 C/T cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs1215050 0.791 rs592053 chr4:98732220 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs769267 1.000 rs7247309 chr19:19439631 A/T cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs3796352 1.000 rs2336541 chr3:52974630 G/C cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT trans rs17834679 0.957 rs59546961 chr19:52270210 G/C cg13034837 chr18:32924525 ZNF24 0.86 6.69 0.51 6.93e-10 Alopecia areata; TGCT cis rs6671200 0.920 rs7555236 chr1:95631314 G/A cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs9814567 1.000 rs7429866 chr3:134236306 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs57221529 0.766 rs72706608 chr5:559203 C/T cg09021430 chr5:549028 NA -0.4 -5.46 -0.44 2.44e-7 Lung disease severity in cystic fibrosis; TGCT cis rs7267979 1.000 rs422424 chr20:25445446 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11690935 0.959 rs973889 chr2:172579954 A/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs854765 0.929 rs2955360 chr17:17974887 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.66 -6.3 -0.49 4.75e-9 Total body bone mineral density; TGCT trans rs7180079 0.502 rs6494466 chr15:64508763 A/G cg06219821 chr1:12290367 VPS13D -0.68 -6.75 -0.52 4.94e-10 Monocyte count; TGCT cis rs7666738 0.830 rs2865989 chr4:99067532 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11673344 0.504 rs4806409 chr19:37588825 A/G cg08039142 chr19:36980659 ZNF566 0.49 4.48 0.37 1.68e-5 Obesity-related traits; TGCT cis rs13191362 0.872 rs35672319 chr6:163245464 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.67 4.66 0.39 8.09e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg17971929 chr21:40555470 PSMG1 -0.72 -6.06 -0.48 1.5e-8 Cognitive function; TGCT cis rs636291 0.517 rs670666 chr1:10549380 C/T cg17425144 chr1:10567563 PEX14 -0.53 -7.41 -0.55 1.73e-11 Prostate cancer; TGCT trans rs3780486 1.000 rs12342831 chr9:33124872 A/G cg04842962 chr6:43655489 MRPS18A 1.13 11.53 0.72 2.42e-21 IgG glycosylation; TGCT cis rs10114408 0.959 rs10992953 chr9:96646988 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2688608 0.592 rs12253482 chr10:75496130 G/A cg15838173 chr10:75533400 FUT11 -0.31 -5.08 -0.42 1.33e-6 Inflammatory bowel disease; TGCT cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg11502198 chr6:26597334 ABT1 0.54 4.94 0.41 2.49e-6 Intelligence (multi-trait analysis); TGCT cis rs9914544 0.602 rs4924929 chr17:18714241 G/A cg26306683 chr17:18585705 ZNF286B 0.52 4.83 0.4 4.01e-6 Educational attainment (years of education); TGCT cis rs933688 1.000 rs12188467 chr5:90765632 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.97 9.16 0.64 1.38e-15 Smoking behavior; TGCT cis rs7447593 0.666 rs10866705 chr5:176801131 G/T cg17509989 chr5:176798049 RGS14 -0.69 -8.58 -0.61 3.29e-14 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs17401966 0.838 rs35257796 chr1:10267390 T/A cg19773385 chr1:10388646 KIF1B -0.21 -4.57 -0.38 1.18e-5 Hepatocellular carcinoma; TGCT cis rs1997103 1.000 rs10252413 chr7:55396740 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2072499 0.966 rs6427304 chr1:156156789 A/G cg24450063 chr1:156163899 SLC25A44 1.15 15.99 0.82 6.37e-32 Testicular germ cell tumor; TGCT cis rs9993613 0.875 rs12642941 chr4:73513158 A/G cg15102770 chr4:73434591 ADAMTS3 0.5 4.62 0.38 9.58e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs12497850 0.897 rs9681717 chr3:48872998 A/G cg18654377 chr3:49208889 KLHDC8B -0.41 -5.47 -0.44 2.41e-7 Parkinson's disease; TGCT cis rs4653767 0.573 rs708772 chr1:226912891 A/G cg11238820 chr1:226410871 MIXL1 0.32 4.55 0.38 1.24e-5 Parkinson's disease; TGCT cis rs1371867 0.810 rs2860518 chr8:101238120 G/T cg06002616 chr8:101225028 SPAG1 0.51 5.86 0.47 3.95e-8 Atrioventricular conduction; TGCT cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT cis rs35160687 0.901 rs12472390 chr2:86475083 T/C cg04877910 chr2:85804641 VAMP8 0.34 4.48 0.37 1.67e-5 Night sleep phenotypes; TGCT cis rs7772486 0.790 rs2254288 chr6:146204470 G/A cg05347473 chr6:146136440 FBXO30 0.5 4.9 0.4 2.92e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs4555082 0.874 rs56263609 chr14:105756944 C/T cg01266790 chr14:105781312 PACS2 0.59 4.86 0.4 3.45e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs1670533 0.932 rs13140571 chr4:1054358 T/C cg27284194 chr4:1044797 NA 0.69 5.71 0.46 7.76e-8 Recombination rate (females); TGCT cis rs362272 0.524 rs881816 chr4:3365366 A/G cg06533319 chr4:3265114 C4orf44 -0.28 -5.69 -0.46 8.58e-8 Serum sulfate level; TGCT cis rs16867321 1.000 rs1358520 chr2:181440081 C/T cg23363182 chr2:181467187 NA -0.38 -5.39 -0.44 3.41e-7 Obesity; TGCT cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg16414030 chr3:133502952 NA -0.5 -7.01 -0.53 1.39e-10 Iron status biomarkers; TGCT cis rs4665809 0.838 rs7565843 chr2:26292912 G/C cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs4319547 0.741 rs4758644 chr12:122943915 A/C cg05707623 chr12:122985044 ZCCHC8 -0.58 -4.64 -0.38 8.72e-6 Body mass index; TGCT cis rs7267979 1.000 rs2184000 chr20:25395878 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4665809 0.590 rs7606351 chr2:26292545 A/C cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs10197940 0.571 rs13393021 chr2:152413258 A/C cg19508488 chr2:152266495 RIF1 0.7 6.39 0.5 2.98e-9 Lung cancer; TGCT cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg09436375 chr6:42928200 GNMT -0.4 -5.2 -0.42 8.08e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs6088590 1.000 rs2180276 chr20:33360785 T/A cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs12615966 1.000 rs6543268 chr2:105370105 G/C cg16465502 chr2:105461796 NA 0.77 4.56 0.38 1.19e-5 Pancreatic cancer; TGCT cis rs12210905 1.000 rs858975 chr6:27155623 G/A cg22243996 chr6:26757644 NA -0.62 -4.65 -0.39 8.47e-6 Hip circumference adjusted for BMI; TGCT cis rs4665809 1.000 rs2289022 chr2:26350136 G/T cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs7246657 0.722 rs10403173 chr19:38078680 G/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs2797160 0.967 rs2797162 chr6:126011381 G/T cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs6138458 1.000 rs6114988 chr20:24977586 C/T cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs3820928 0.874 rs10166456 chr2:227900113 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs644799 1.000 rs560854 chr11:95584905 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.85 9.0 0.63 3.27e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs56309584 0.673 rs12451139 chr17:8119626 G/T cg08322244 chr17:8066669 VAMP2 -0.56 -5.2 -0.42 7.95e-7 Initial pursuit acceleration; TGCT cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg18230493 chr5:56204884 C5orf35 -0.67 -5.71 -0.46 8e-8 Initial pursuit acceleration; TGCT cis rs9814567 1.000 rs9813774 chr3:134227100 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6671200 0.607 rs7528790 chr1:95709074 A/G cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs899997 1.000 rs11072800 chr15:79045857 C/T cg00061860 chr15:78953028 NA 0.27 5.04 0.41 1.6e-6 Coronary artery disease or large artery stroke; TGCT cis rs6910741 1.000 rs6910741 chr6:25895575 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.91 6.53 0.51 1.5e-9 Blood pressure; TGCT cis rs10057188 1.000 rs13436853 chr5:77870977 A/C cg06873401 chr5:77792105 LHFPL2 -0.22 -4.44 -0.37 1.94e-5 Pulse pressure; TGCT cis rs155076 1.000 rs261404 chr13:21858162 T/G cg07022442 chr13:21864356 NA 0.31 4.81 0.4 4.31e-6 White matter hyperintensity burden; TGCT cis rs7246657 0.679 rs12461113 chr19:38083188 G/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg16497277 chr3:49208875 KLHDC8B 0.53 5.13 0.42 1.09e-6 Menarche (age at onset); TGCT cis rs12048904 0.595 rs2295280 chr1:101342497 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.66 6.92 0.53 2.11e-10 Multiple sclerosis; TGCT cis rs3935685 0.874 rs56370262 chr15:77996708 G/C cg25212270 chr15:78015279 NA 0.26 5.58 0.45 1.47e-7 Intelligence (multi-trait analysis); TGCT cis rs7909074 1.000 rs4948927 chr10:45397071 G/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.33 -0.43 4.38e-7 Mean corpuscular volume; TGCT cis rs12142240 0.845 rs4313342 chr1:46801904 T/C cg00530320 chr1:46809349 NSUN4 0.27 5.42 0.44 3.03e-7 Menopause (age at onset); TGCT cis rs1971762 0.966 rs11170631 chr12:54041192 T/C cg16917193 chr12:54089295 NA 0.55 4.57 0.38 1.18e-5 Height; TGCT cis rs9902453 0.904 rs12103671 chr17:28408217 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -7.98 -0.58 8.19e-13 Coffee consumption (cups per day); TGCT cis rs7904368 0.754 rs7076779 chr10:16852667 C/T cg14835575 chr10:16859367 RSU1 0.67 7.67 0.57 4.27e-12 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs3617 0.625 rs7652667 chr3:52866535 C/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs877282 0.853 rs10904544 chr10:756966 A/G cg22713356 chr15:30763199 NA 1.13 8.3 0.6 1.52e-13 Uric acid levels; TGCT cis rs7100689 0.646 rs1934692 chr10:82125734 C/A cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs394563 0.619 rs4895787 chr6:149646500 G/A cg16235748 chr6:149772707 ZC3H12D 0.43 4.98 0.41 2.05e-6 Dupuytren's disease; TGCT cis rs7178572 0.568 rs8037561 chr15:77680462 A/G cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs941873 0.868 rs12780295 chr10:81115438 G/A cg09469691 chr10:81107165 PPIF 0.55 5.42 0.44 2.93e-7 Height; TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg08859206 chr1:53392774 SCP2 -0.43 -6.41 -0.5 2.76e-9 Monocyte count; TGCT cis rs9388451 0.505 rs6920965 chr6:126179111 G/A cg05901451 chr6:126070800 HEY2 -0.73 -7.38 -0.55 2.05e-11 Brugada syndrome; TGCT cis rs860295 0.580 rs867550 chr1:155880391 T/C cg05700447 chr1:155978627 NA 0.23 4.72 0.39 6.14e-6 Body mass index; TGCT cis rs7017914 0.934 rs17689585 chr8:71818801 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs7639513 0.767 rs6784168 chr3:12702847 T/G cg23032965 chr3:12705835 RAF1 0.77 8.53 0.61 4.28e-14 Itch intensity from mosquito bite; TGCT cis rs7312933 0.558 rs3747560 chr12:42719890 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.7 -0.46 8.16e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6430585 0.527 rs76380759 chr2:136438517 G/A cg07169764 chr2:136633963 MCM6 0.97 8.66 0.61 2.06e-14 Corneal structure; TGCT cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg22166914 chr1:53195759 ZYG11B -0.47 -8.65 -0.61 2.18e-14 Monocyte count; TGCT cis rs12477438 0.834 rs10179043 chr2:99687490 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.68 -5.88 -0.47 3.51e-8 Chronic sinus infection; TGCT cis rs6785206 0.527 rs35216064 chr3:128643155 C/T cg25356066 chr3:128598488 ACAD9 -0.71 -4.45 -0.37 1.85e-5 Lymphocyte percentage of white cells; TGCT cis rs10986311 0.681 rs10986291 chr9:127016271 A/T cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.47 -0.37 1.73e-5 Vitiligo; TGCT cis rs875971 0.862 rs4368860 chr7:65608482 C/G cg11764359 chr7:65958608 NA -0.56 -5.09 -0.42 1.31e-6 Aortic root size; TGCT cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg05896524 chr21:47604654 C21orf56 -0.46 -4.93 -0.4 2.6e-6 Testicular germ cell tumor; TGCT cis rs28595532 0.841 rs116329146 chr4:119733438 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs319204 0.959 rs319194 chr5:146268717 C/T cg25021259 chr5:146258546 PPP2R2B 0.37 4.66 0.39 8.02e-6 Schizophrenia; TGCT cis rs295140 1.000 rs11888462 chr2:201160499 G/T cg04283868 chr2:201171347 SPATS2L 0.63 6.36 0.5 3.56e-9 QT interval; TGCT cis rs2228479 0.850 rs11648689 chr16:89806732 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7226408 0.857 rs61044601 chr18:34440179 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs806215 1.000 rs327511 chr7:127257261 G/T cg25922125 chr7:127225783 GCC1 0.47 4.79 0.4 4.62e-6 Type 2 diabetes; TGCT cis rs9611565 0.649 rs2064189 chr22:42127999 A/G cg06481639 chr22:41940642 POLR3H 0.56 4.78 0.39 4.79e-6 Vitiligo; TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg11494091 chr17:61959527 GH2 0.61 14.46 0.79 2.18e-28 Prudent dietary pattern; TGCT cis rs2153535 0.580 rs2143356 chr6:8517675 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9814567 0.806 rs2293294 chr3:134322814 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.78 7.26 0.55 3.68e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.65 -0.39 8.45e-6 Prudent dietary pattern; TGCT trans rs941408 1.000 rs1640271 chr19:2799979 C/T cg19676328 chr12:49525230 TUBA1B -0.78 -7.55 -0.56 8.09e-12 Total cholesterol levels; TGCT cis rs8103278 1.000 rs9807819 chr19:46239598 C/T cg11657440 chr19:46296263 DMWD -0.53 -5.08 -0.42 1.34e-6 Coronary artery disease; TGCT cis rs9467711 0.606 rs12174639 chr6:26373121 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6500550 0.636 rs2158443 chr16:3685782 C/G cg07396092 chr16:3662230 BTBD12 0.5 4.44 0.37 2e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;White blood cell count;Neutrophil count; TGCT cis rs6582630 0.519 rs7305570 chr12:38349285 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.33e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.800 rs7683737 chr4:99070880 A/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4986172 0.655 rs1044977 chr17:43227214 T/C cg10701640 chr17:43249399 NA 0.55 6.58 0.51 1.18e-9 Height; TGCT cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg02725872 chr8:58115012 NA -0.4 -4.83 -0.4 3.92e-6 Developmental language disorder (linguistic errors); TGCT cis rs6484504 0.532 rs11031330 chr11:31275073 G/A cg26647111 chr11:31128758 NA -0.35 -4.85 -0.4 3.58e-6 Red blood cell count; TGCT cis rs769267 1.000 rs8103197 chr19:19443466 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs10431058 1.000 rs10431058 chr11:107481518 A/G cg18204760 chr11:107461044 ELMOD1;LOC643923 -0.66 -6.36 -0.5 3.47e-9 Common traits (Other); TGCT cis rs425277 0.628 rs262662 chr1:2085033 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.46 -0.37 1.81e-5 Height; TGCT cis rs7267979 0.780 rs6050679 chr20:25537827 A/T cg03522245 chr20:25566470 NINL 0.58 6.02 0.48 1.85e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9291683 0.546 rs12504565 chr4:10045145 G/A cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Bone mineral density; TGCT cis rs35306767 0.903 rs12244253 chr10:889320 G/T cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.32 -5.13 -0.42 1.11e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg00149659 chr3:10157352 C3orf10 0.97 5.98 0.47 2.19e-8 Alzheimer's disease; TGCT cis rs2730245 1.000 rs2730245 chr7:158724789 G/C cg24397884 chr7:158709396 WDR60 -0.4 -5.3 -0.43 5.05e-7 Height; TGCT cis rs6087990 0.899 rs998382 chr20:31384136 C/T cg13636640 chr20:31349939 DNMT3B -1.06 -15.55 -0.81 6.6e-31 Ulcerative colitis; TGCT cis rs7659604 0.605 rs1507994 chr4:122749541 C/T cg20573242 chr4:122745356 CCNA2 0.59 5.41 0.44 3.11e-7 Type 2 diabetes; TGCT cis rs7909074 0.898 rs10793565 chr10:45388231 G/C cg05187965 chr10:45406764 TMEM72 -0.25 -5.31 -0.43 4.96e-7 Mean corpuscular volume; TGCT cis rs7020830 0.931 rs9775431 chr9:37130433 G/A cg14294708 chr9:37120828 ZCCHC7 1.22 18.16 0.85 9.64e-37 Schizophrenia; TGCT cis rs910316 0.737 rs175045 chr14:75475275 A/C cg11812906 chr14:75593930 NEK9 -0.59 -5.25 -0.43 6.35e-7 Height; TGCT cis rs7267979 1.000 rs11100 chr20:25281184 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs877282 0.853 rs7092805 chr10:756246 G/A cg22713356 chr15:30763199 NA 1.12 8.58 0.61 3.29e-14 Uric acid levels; TGCT cis rs926938 0.618 rs1286555 chr1:115361896 C/T cg12756093 chr1:115239321 AMPD1 -0.42 -6.06 -0.48 1.53e-8 Autism; TGCT cis rs877282 0.891 rs12767062 chr10:797961 C/T cg17470449 chr10:769945 NA 0.3 4.72 0.39 6.34e-6 Uric acid levels; TGCT cis rs2806561 0.765 rs1612905 chr1:23510023 G/T cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs10504229 0.906 rs2270609 chr8:58194684 G/A cg22535103 chr8:58192502 C8orf71 -0.39 -4.5 -0.37 1.54e-5 Developmental language disorder (linguistic errors); TGCT cis rs9393777 0.513 rs9393737 chr6:26617306 A/G cg15659132 chr6:26577336 NA 0.72 5.29 0.43 5.24e-7 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.692 rs4442773 chr15:77031633 T/C cg22467129 chr15:76604101 ETFA -0.44 -4.93 -0.4 2.62e-6 Blood metabolite levels; TGCT cis rs8037137 0.915 rs76119208 chr15:91535329 G/T cg22570213 chr15:91497863 RCCD1 0.5 4.65 0.39 8.27e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs9814567 0.727 rs7641798 chr3:134345719 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -5.95 -0.47 2.58e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6921919 0.583 rs16894060 chr6:28362471 T/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs72843506 1.000 rs7223910 chr17:19982768 G/A cg21163262 chr17:19349762 NA 0.23 4.51 0.38 1.51e-5 Schizophrenia; TGCT cis rs492146 0.765 rs367836 chr6:52843131 G/T cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs11249608 0.600 rs13359570 chr5:178449249 T/G cg21905437 chr5:178450457 ZNF879 0.45 4.48 0.37 1.67e-5 Pubertal anthropometrics; TGCT cis rs7772486 0.692 rs2265915 chr6:146194332 A/T cg05347473 chr6:146136440 FBXO30 0.54 5.06 0.41 1.47e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2075371 0.933 rs1833475 chr7:133958263 C/T cg11752832 chr7:134001865 SLC35B4 0.68 5.89 0.47 3.32e-8 Mean platelet volume; TGCT cis rs1865760 1.000 rs7739966 chr6:25906040 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs2762353 0.546 rs2205936 chr6:25685492 G/C cg17042849 chr6:26104293 HIST1H4C -0.56 -4.97 -0.41 2.14e-6 Blood metabolite levels; TGCT cis rs2439831 0.850 rs2957637 chr15:43951118 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.72 4.64 0.38 8.81e-6 Lung cancer in ever smokers; TGCT cis rs7192750 0.586 rs2288031 chr16:71902142 C/A cg06353428 chr16:71660113 MARVELD3 0.8 7.26 0.55 3.8e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2404602 1.000 rs12594541 chr15:76834368 G/A cg26408565 chr15:76604113 ETFA -0.41 -5.19 -0.42 8.3e-7 Blood metabolite levels; TGCT cis rs9399135 0.967 rs4896119 chr6:135293391 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.75 0.39 5.5e-6 Red blood cell count; TGCT cis rs55823223 0.564 rs1463485 chr17:73851791 C/G cg08125733 chr17:73851984 WBP2 0.87 8.8 0.62 1e-14 Psoriasis; TGCT cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg01411255 chr17:61851458 DDX42;CCDC47 -1.12 -14.29 -0.79 5.53e-28 Height; TGCT cis rs2816062 0.775 rs2745315 chr1:18897118 G/A cg18795169 chr1:18902165 NA -0.58 -13.28 -0.77 1.36e-25 Urate levels in lean individuals; TGCT cis rs12477438 0.765 rs12612688 chr2:99613091 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.56 -0.56 7.93e-12 Chronic sinus infection; TGCT cis rs72945132 0.825 rs7941965 chr11:70213182 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs12477438 0.501 rs11685756 chr2:99766215 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg11890956 chr21:40555474 PSMG1 -0.72 -6.51 -0.5 1.67e-9 Cognitive function; TGCT cis rs5769765 0.955 rs9616366 chr22:50301178 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -10.56 -0.69 5.6e-19 Schizophrenia; TGCT cis rs1156327 0.655 rs179235 chr16:19324733 G/A cg02978544 chr16:19716338 NA 0.44 4.62 0.38 9.3e-6 Periodontal disease-related phenotypes; TGCT cis rs4273100 1.000 rs16960499 chr17:19203032 A/G cg01534423 chr17:18965556 NA 0.92 5.96 0.47 2.42e-8 Schizophrenia; TGCT cis rs7954584 0.531 rs6486781 chr12:122318985 A/C cg22168489 chr12:122356033 WDR66 0.19 4.61 0.38 9.95e-6 Mean corpuscular volume; TGCT cis rs13191362 0.507 rs1954806 chr6:163051858 G/C cg21926612 chr6:163149169 PACRG;PARK2 -0.61 -5.48 -0.44 2.27e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg21724239 chr8:58056113 NA 0.41 4.87 0.4 3.33e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.817 rs2748491 chr6:146327759 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.48 -0.37 1.67e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2637266 0.630 rs7095225 chr10:78452623 G/T cg18941641 chr10:78392320 NA 0.4 4.8 0.4 4.51e-6 Pulmonary function; TGCT cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg23205692 chr1:25664452 TMEM50A -0.47 -4.97 -0.41 2.22e-6 Erythrocyte sedimentation rate; TGCT cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.91 0.4 2.83e-6 Height; TGCT cis rs7917772 0.560 rs729023 chr10:104341887 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.61 -6.01 -0.47 1.94e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6952808 0.636 rs6964522 chr7:1953523 C/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.51 -0.38 1.5e-5 Bipolar disorder and schizophrenia; TGCT cis rs9467711 0.591 rs13202688 chr6:25993469 A/G cg16898833 chr6:26189333 HIST1H4D 1.36 6.0 0.47 2.05e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs4845570 0.850 rs4504897 chr1:151766851 T/A cg07092448 chr1:151763213 TDRKH 1.06 9.06 0.63 2.36e-15 Coronary artery disease; TGCT cis rs9486719 0.843 rs2499787 chr6:96841762 G/C cg18709589 chr6:96969512 KIAA0776 0.77 5.12 0.42 1.16e-6 Migraine;Coronary artery disease; TGCT cis rs11190604 1.000 rs11190592 chr10:102291059 T/C cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs904251 0.523 rs2776870 chr6:37481364 C/A cg25019722 chr6:37503610 NA -0.53 -8.19 -0.59 2.75e-13 Cognitive performance; TGCT cis rs1865760 1.000 rs12209482 chr6:25909229 T/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs13217239 0.646 rs10946888 chr6:26951678 A/G cg15659132 chr6:26577336 NA 0.54 5.45 0.44 2.61e-7 Schizophrenia; TGCT cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg23708337 chr7:1209742 NA 0.56 5.09 0.42 1.31e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12681287 0.752 rs7846635 chr8:87304281 G/A cg27223183 chr8:87520930 FAM82B -0.82 -5.79 -0.46 5.37e-8 Caudate activity during reward; TGCT cis rs1843834 0.539 rs12694643 chr2:225446603 A/G cg22455342 chr2:225449267 CUL3 1.05 10.96 0.7 5.87e-20 IgE levels in asthmatics (D.p. specific); TGCT cis rs9611565 0.592 rs5996038 chr22:41965300 T/C cg03806693 chr22:41940476 POLR3H -1.08 -11.36 -0.71 6.34e-21 Vitiligo; TGCT cis rs992157 0.697 rs13384682 chr2:219069137 G/A cg00012203 chr2:219082015 ARPC2 0.81 10.19 0.68 4.34e-18 Colorectal cancer; TGCT cis rs7611238 0.560 rs62287069 chr3:195027645 T/C cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.94e-6 Body mass index; TGCT cis rs2075371 0.796 rs35336643 chr7:134010640 G/A cg11752832 chr7:134001865 SLC35B4 0.7 5.97 0.47 2.27e-8 Mean platelet volume; TGCT cis rs360798 0.512 rs7562149 chr2:63008414 A/G cg17519650 chr2:63277830 OTX1 -0.67 -6.26 -0.49 5.8e-9 Coronary artery disease; TGCT cis rs3849570 0.615 rs6778265 chr3:81985745 C/T cg07356753 chr3:81810745 GBE1 0.58 5.09 0.42 1.3e-6 Waist circumference;Body mass index; TGCT trans rs7824557 0.564 rs2736302 chr8:11236419 T/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs10464366 0.510 rs62442212 chr7:39146896 A/C cg18850127 chr7:39170497 POU6F2 0.28 6.61 0.51 1.03e-9 IgG glycosylation; TGCT cis rs10992471 0.528 rs3739606 chr9:95237222 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -4.94 -0.41 2.47e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9811920 0.683 rs16841874 chr3:99720564 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.44 5.28 0.43 5.61e-7 Axial length; TGCT cis rs10875595 0.775 rs66998469 chr5:140659960 T/C cg24830062 chr5:140700576 TAF7 -0.6 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs1461503 0.838 rs7107012 chr11:122829813 G/A cg27398637 chr11:122830231 C11orf63 -0.41 -4.77 -0.39 5.14e-6 Menarche (age at onset); TGCT cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg09904177 chr6:26538194 HMGN4 -0.68 -6.55 -0.51 1.41e-9 Intelligence (multi-trait analysis); TGCT cis rs10949834 0.529 rs150861 chr7:73524901 T/C cg07137043 chr7:73588983 EIF4H 0.7 5.44 0.44 2.71e-7 Verbal memory performance (residualized delayed recall change); TGCT trans rs1496653 0.602 rs71322171 chr3:23369360 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs6840360 0.571 rs62327278 chr4:152558790 G/C cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.738 rs10489769 chr1:46806703 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.78 -0.39 4.78e-6 Menopause (age at onset); TGCT cis rs9388451 0.839 rs4897157 chr6:126102981 A/T cg10911889 chr6:126070802 HEY2 0.51 5.33 0.43 4.47e-7 Brugada syndrome; TGCT cis rs8177253 1.000 rs8177271 chr3:133482230 G/A cg11941060 chr3:133502564 NA -0.29 -6.15 -0.48 9.6e-9 Iron status biomarkers; TGCT cis rs9549367 0.713 rs3024745 chr13:113821598 A/G cg00898013 chr13:113819073 PROZ -0.51 -6.11 -0.48 1.2e-8 Platelet distribution width; TGCT cis rs6893807 0.623 rs112862634 chr5:87970352 G/C cg24804195 chr5:87968844 LOC645323 0.77 4.58 0.38 1.11e-5 Body mass index; TGCT cis rs6433857 0.657 rs2368178 chr2:181501938 T/C cg23363182 chr2:181467187 NA -0.34 -5.16 -0.42 9.57e-7 Body mass index; TGCT cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg06238570 chr21:40685208 BRWD1 -0.82 -8.86 -0.62 7.17e-15 Cognitive function; TGCT cis rs1878931 0.696 rs35984213 chr16:3451030 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 12.11 0.74 9.25e-23 Body mass index (adult); TGCT cis rs9682041 0.877 rs12489967 chr3:170073339 A/C cg07589077 chr3:170072950 NA 0.29 5.01 0.41 1.82e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs346785 1.000 rs164106 chr17:74290566 C/A cg09812376 chr17:74270190 QRICH2 -0.39 -5.96 -0.47 2.43e-8 White matter hyperintensities in ischemic stroke; TGCT cis rs2242116 1.000 rs1138518 chr3:46944274 T/C cg27129171 chr3:47204927 SETD2 0.61 5.84 0.46 4.25e-8 Birth weight; TGCT cis rs12615966 0.584 rs72830474 chr2:105414217 C/T cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs751728 0.664 rs943478 chr6:33750940 T/A cg13859433 chr6:33739653 LEMD2 -0.32 -5.68 -0.45 8.97e-8 Crohn's disease; TGCT cis rs2469997 0.843 rs2470013 chr8:120360758 G/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs3091242 0.900 rs35345536 chr1:25766488 A/G cg09222892 chr1:25734099 RHCE -0.42 -6.88 -0.53 2.58e-10 Erythrocyte sedimentation rate; TGCT cis rs2486012 1.000 rs2231283 chr1:44450737 C/G cg12908607 chr1:44402522 ARTN 0.73 5.95 0.47 2.6e-8 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg22535103 chr8:58192502 C8orf71 -0.46 -5.16 -0.42 9.68e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs115279324 chr4:99042114 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12908161 1.000 rs12903134 chr15:85337699 T/A cg17173187 chr15:85201210 NMB 0.57 6.39 0.5 3.07e-9 Schizophrenia; TGCT cis rs7528419 0.895 rs599839 chr1:109822166 A/G cg00908766 chr1:109817496 CELSR2 -0.45 -4.69 -0.39 7.1e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs7267979 1.000 rs6050566 chr20:25351071 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1218582 0.774 rs2335409 chr1:154916106 G/A cg24250549 chr1:154909240 PMVK 0.57 5.48 0.44 2.28e-7 Prostate cancer; TGCT cis rs1008375 1.000 rs1558378 chr4:17650351 T/C cg16339924 chr4:17578868 LAP3 0.67 5.55 0.45 1.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg12667521 chr19:29218732 NA 0.55 5.9 0.47 3.29e-8 Methadone dose in opioid dependence; TGCT cis rs9443189 0.615 rs618239 chr6:76350038 A/G cg01950844 chr6:76311363 SENP6 1.0 6.26 0.49 5.74e-9 Prostate cancer; TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg25767906 chr1:53392781 SCP2 -0.53 -6.21 -0.49 7.34e-9 Monocyte count; TGCT cis rs10493773 0.609 rs11161656 chr1:86182414 A/G cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs7772486 0.641 rs2777485 chr6:146334377 G/A cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.2e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs6532724 chr4:99060993 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg02353165 chr6:42928485 GNMT 0.94 9.65 0.66 8.78e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs936229 0.813 rs3784790 chr15:75081745 G/C cg10253484 chr15:75165896 SCAMP2 -0.67 -5.38 -0.43 3.64e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs875971 0.862 rs6460293 chr7:65810192 C/A cg11764359 chr7:65958608 NA -0.55 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs7666738 0.830 rs11721726 chr4:98996314 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9921338 0.961 rs12934968 chr16:11414066 C/A cg00044050 chr16:11439710 C16orf75 0.95 7.39 0.55 1.92e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4901869 0.897 rs12878587 chr14:59339378 C/G cg02291164 chr14:59296302 NA 0.24 4.7 0.39 6.86e-6 Panic disorder; TGCT cis rs72945132 0.882 rs1061328 chr11:70185325 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs1670533 1.000 rs2045069 chr4:1052206 T/C cg20887711 chr4:1340912 KIAA1530 0.73 5.74 0.46 6.77e-8 Recombination rate (females); TGCT trans rs561341 0.941 rs17780080 chr17:30343146 G/A cg20587970 chr11:113659929 NA -1.09 -13.5 -0.77 4.23e-26 Hip circumference adjusted for BMI; TGCT cis rs453301 0.653 rs2956244 chr8:8885166 A/G cg06636001 chr8:8085503 FLJ10661 0.81 7.06 0.54 1.06e-10 Joint mobility (Beighton score); TGCT cis rs875971 0.619 rs10278371 chr7:66051540 C/A cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs4074961 0.669 rs4652964 chr1:38078300 A/G cg17933807 chr1:38061675 GNL2 0.96 11.42 0.72 4.35e-21 Axial length; TGCT cis rs11623869 0.553 rs11627567 chr14:103851775 C/T cg26031613 chr14:104095156 KLC1 0.68 5.41 0.44 3.11e-7 Bone mineral density; TGCT cis rs2066819 1.000 rs79101914 chr12:56729739 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs8062405 0.573 rs8045689 chr16:28988269 C/T cg01117621 chr16:28073818 GSG1L -0.37 -4.73 -0.39 6.11e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2288884 0.943 rs12611112 chr19:52574939 G/A cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs4242434 0.597 rs1877675 chr8:22533947 C/T cg03733263 chr8:22462867 KIAA1967 -1.02 -13.72 -0.78 1.25e-26 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs1729951 0.514 rs75977 chr3:136700549 C/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs259282 0.583 rs3760938 chr19:33106907 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.34 0.43 4.25e-7 Schizophrenia; TGCT cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.89 0.4 3e-6 Platelet count; TGCT cis rs7772486 0.597 rs9386136 chr6:146158300 A/T cg13319975 chr6:146136371 FBXO30 -0.67 -6.06 -0.48 1.53e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6545883 1.000 rs778758 chr2:61782161 T/C cg15711740 chr2:61764176 XPO1 -0.56 -5.08 -0.42 1.35e-6 Tuberculosis; TGCT cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.68e-9 Blood metabolite levels; TGCT cis rs11696501 0.739 rs4812938 chr20:44249919 T/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs7945705 0.902 rs2012696 chr11:8995818 A/C cg21881798 chr11:8931708 C11orf17;ST5 0.47 5.37 0.43 3.7e-7 Hemoglobin concentration; TGCT cis rs10465746 0.967 rs11163876 chr1:84440605 T/C cg10977910 chr1:84465055 TTLL7 0.65 6.54 0.51 1.44e-9 Obesity-related traits; TGCT cis rs10992471 0.580 rs7847534 chr9:95282653 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.63 -0.45 1.13e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7824557 0.602 rs7828711 chr8:11205665 G/C cg21775007 chr8:11205619 TDH 0.71 6.7 0.52 6.36e-10 Retinal vascular caliber; TGCT cis rs6558174 1.000 rs6558174 chr8:22492129 A/G cg03733263 chr8:22462867 KIAA1967 0.63 4.88 0.4 3.17e-6 Breast cancer; TGCT cis rs826838 1.000 rs826851 chr12:39112639 A/G cg26384229 chr12:38710491 ALG10B -0.92 -8.47 -0.61 5.96e-14 Heart rate; TGCT cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg03806693 chr22:41940476 POLR3H 1.16 13.41 0.77 7.02e-26 Vitiligo; TGCT cis rs17102423 0.755 rs11158572 chr14:65577411 C/T cg11161011 chr14:65562177 MAX -0.54 -7.49 -0.56 1.15e-11 Obesity-related traits; TGCT cis rs13191362 0.938 rs59067610 chr6:163030440 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.65 5.32 0.43 4.7e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7172809 0.573 rs4886865 chr15:77686876 C/T cg22256960 chr15:77711686 NA -0.5 -4.74 -0.39 5.82e-6 Glucose homeostasis traits; TGCT cis rs910316 0.967 rs4899545 chr14:75568138 A/G cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs13326165 0.760 rs9861879 chr3:52424001 A/G cg27565382 chr3:53032988 SFMBT1 0.38 5.06 0.41 1.5e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs116095464 0.558 rs60251075 chr5:245292 T/C cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT trans rs941408 0.928 rs2260414 chr19:2796316 G/A cg19676328 chr12:49525230 TUBA1B -0.75 -7.31 -0.55 2.84e-11 Total cholesterol levels; TGCT cis rs875971 0.964 rs6978429 chr7:65959876 T/G cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs1729951 0.514 rs75977 chr3:136700549 C/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT trans rs324780 0.544 rs2220575 chr12:83906245 G/A cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.42e-10 Vertical cup-disc ratio; TGCT cis rs60843830 1.000 rs4497901 chr2:239969 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.82 0.52 3.58e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs858239 0.899 rs10085838 chr7:23298415 C/A cg05602783 chr7:23145260 KLHL7 -0.67 -5.24 -0.43 6.72e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs140365914 1 rs140365914 chr7:155106570 C/T cg14927855 chr7:155151427 NA 0.49 6.82 0.52 3.51e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7226408 0.802 rs72894332 chr18:34717721 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6582630 0.555 rs10880602 chr12:38505660 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.75 0.57 2.83e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs7119 0.717 rs7180732 chr15:77829921 G/A cg27398640 chr15:77910606 LINGO1 -0.26 -4.73 -0.39 6.02e-6 Type 2 diabetes; TGCT cis rs6952808 0.564 rs73038441 chr7:2139286 T/C cg04267008 chr7:1944627 MAD1L1 -0.36 -4.82 -0.4 4.05e-6 Bipolar disorder and schizophrenia; TGCT cis rs1372520 0.684 rs356191 chr4:90688120 G/A cg15133208 chr4:90757351 SNCA 0.47 5.58 0.45 1.43e-7 Neuroticism; TGCT cis rs3820068 0.705 rs927206 chr1:15893338 C/T cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9325144 0.600 rs10785615 chr12:38733627 G/C cg26384229 chr12:38710491 ALG10B 0.62 5.66 0.45 1e-7 Morning vs. evening chronotype; TGCT cis rs79149102 0.579 rs8033125 chr15:75374970 G/C cg09165964 chr15:75287851 SCAMP5 -1.0 -5.42 -0.44 3.02e-7 Lung cancer; TGCT cis rs8177253 1.000 rs1358023 chr3:133484393 T/C cg01448562 chr3:133502909 NA -0.33 -6.67 -0.51 7.6e-10 Iron status biomarkers; TGCT cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg22963979 chr7:1858916 MAD1L1 -0.45 -7.41 -0.55 1.74e-11 Bipolar disorder and schizophrenia; TGCT cis rs9913156 0.517 rs2326118 chr17:4611851 C/T cg19197139 chr17:4613644 ARRB2 0.64 5.78 0.46 5.58e-8 Lymphocyte counts; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg19822892 chr17:4507469 SMTNL2 0.8 7.15 0.54 6.58e-11 Gambling; TGCT cis rs17826219 0.568 rs11658027 chr17:29094882 A/G cg13385521 chr17:29058706 SUZ12P -0.84 -4.89 -0.4 3.06e-6 Body mass index; TGCT cis rs2637266 1.000 rs2395384 chr10:78335329 G/A cg18941641 chr10:78392320 NA 0.42 4.99 0.41 2e-6 Pulmonary function; TGCT cis rs780096 0.506 rs72819512 chr2:27614449 G/A cg12000995 chr2:27665139 KRTCAP3 -0.37 -4.74 -0.39 5.83e-6 Total body bone mineral density; TGCT cis rs478304 0.934 rs12801731 chr11:65549606 T/C cg27068330 chr11:65405492 SIPA1 0.74 7.34 0.55 2.48e-11 Acne (severe); TGCT cis rs2842992 0.714 rs2495278 chr6:160123674 G/A cg11366901 chr6:160182831 ACAT2 1.0 6.51 0.5 1.64e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs6831352 0.729 rs4699718 chr4:100067791 G/A cg12011299 chr4:100065546 ADH4 -0.43 -5.07 -0.41 1.44e-6 Alcohol dependence; TGCT cis rs1799949 1.000 rs915945 chr17:41179864 C/T cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs9659323 1.000 rs6700415 chr1:119516174 A/T cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.4e-6 Body mass index; TGCT cis rs6904897 0.563 rs4896117 chr6:135229400 T/C cg22676075 chr6:135203613 NA -0.62 -6.66 -0.51 7.82e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs11098499 0.874 rs12502503 chr4:120116255 C/T cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs6460942 1.000 rs2053378 chr7:12405564 C/G cg06484146 chr7:12443880 VWDE -0.63 -5.65 -0.45 1.04e-7 Coronary artery disease; TGCT cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg13695892 chr22:41940480 POLR3H -0.86 -8.12 -0.59 3.89e-13 Vitiligo; TGCT cis rs6714710 0.603 rs11692010 chr2:98397301 C/T cg26665480 chr2:98280029 ACTR1B 0.67 6.22 0.49 7.05e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs9902453 0.845 rs7501472 chr17:28010628 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.19 0.54 5.48e-11 Coffee consumption (cups per day); TGCT cis rs6433895 1.000 rs35543145 chr2:182018115 A/G cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT cis rs6671200 0.573 rs6666528 chr1:95697490 C/A cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs644799 0.710 rs522536 chr11:95528714 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.5 0.61 5.03e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs240764 0.658 rs11155635 chr6:101199367 C/T cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs2841277 0.676 rs10438246 chr14:105410183 T/C cg19901468 chr14:105411992 AHNAK2 -0.27 -5.88 -0.47 3.63e-8 Rheumatoid arthritis; TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg20607798 chr8:58055168 NA 0.59 5.37 0.43 3.72e-7 Developmental language disorder (linguistic errors); TGCT cis rs1018836 0.575 rs17635255 chr8:91518135 A/T cg16814680 chr8:91681699 NA -0.81 -6.34 -0.49 3.95e-9 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs13118159 0.934 rs4974608 chr4:1356780 C/T cg20887711 chr4:1340912 KIAA1530 0.54 4.71 0.39 6.4e-6 Longevity; TGCT cis rs2268241 0.938 rs7283827 chr21:34769904 A/G cg14850771 chr21:34775459 IFNGR2 0.6 5.15 0.42 1.01e-6 Obesity-related traits; TGCT cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg05665937 chr4:1216051 CTBP1 0.22 4.5 0.37 1.53e-5 Obesity-related traits; TGCT cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 7.02 0.53 1.32e-10 Schizophrenia; TGCT cis rs12643440 0.538 rs2041441 chr4:17136036 C/T cg22650099 chr4:17144496 NA -0.45 -4.61 -0.38 9.97e-6 Metabolite levels (Pyroglutamine); TGCT cis rs3820928 0.874 rs1320407 chr2:227867385 G/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs9911578 0.967 rs2611781 chr17:56703124 C/G cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs7611238 0.560 rs11709417 chr3:195004216 A/C cg27323046 chr3:195102265 ACAP2 0.35 4.69 0.39 6.99e-6 Body mass index; TGCT cis rs60843830 1.000 rs36216559 chr2:262335 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.69 0.57 3.87e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs763121 0.925 rs17032 chr22:39130843 C/G cg06022373 chr22:39101656 GTPBP1 0.8 7.96 0.58 9.56e-13 Menopause (age at onset); TGCT cis rs2721811 0.701 rs2721808 chr7:24744309 C/A cg17569154 chr7:24781545 DFNA5 0.22 4.56 0.38 1.2e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7666738 0.830 rs2865978 chr4:99017946 G/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs8033133 0.602 rs4906699 chr15:25321029 A/G cg14481604 chr15:25334117 SNORD116-22 0.24 5.17 0.42 9.26e-7 Blood osmolality (transformed sodium); TGCT cis rs3820068 0.603 rs7516453 chr1:15972558 C/G cg05660106 chr1:15850417 CASP9 0.83 7.73 0.57 3.15e-12 Systolic blood pressure; TGCT cis rs2580764 0.516 rs2860453 chr2:55270485 T/G cg09592903 chr2:55203963 RTN4 0.27 6.06 0.48 1.51e-8 Mean platelet volume; TGCT cis rs79149102 0.579 rs8031545 chr15:75290496 T/C cg09165964 chr15:75287851 SCAMP5 -1.06 -5.82 -0.46 4.83e-8 Lung cancer; TGCT cis rs9653442 0.547 rs1062143 chr2:100659796 A/G cg22139774 chr2:100720529 AFF3 -0.41 -7.32 -0.55 2.67e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs939658 0.683 rs8041222 chr15:79465549 A/G cg17916960 chr15:79447300 NA -0.42 -6.58 -0.51 1.19e-9 Refractive error; TGCT cis rs3796352 0.881 rs13100714 chr3:53074824 T/G cg15956490 chr3:53032818 SFMBT1 0.59 6.75 0.52 5.19e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7254827 0.589 rs2305758 chr19:17163661 A/G cg22949562 chr19:17951967 JAK3 0.27 4.79 0.4 4.66e-6 Mean platelet volume; TGCT cis rs797680 0.786 rs12133576 chr1:93816400 C/T cg17826107 chr1:92977322 EVI5 0.24 5.62 0.45 1.19e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6088580 0.634 rs6088498 chr20:33020446 A/G cg06115741 chr20:33292138 TP53INP2 0.52 4.58 0.38 1.12e-5 Glomerular filtration rate (creatinine); TGCT cis rs13082711 0.595 rs6778612 chr3:27370789 T/C cg02860705 chr3:27208620 NA -0.37 -5.47 -0.44 2.35e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7830371 0.512 rs2978543 chr8:62140844 C/A cg09941713 chr8:61705332 CHD7 0.26 4.45 0.37 1.91e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs11785400 0.793 rs2976399 chr8:143746050 C/T cg10596483 chr8:143751796 JRK 0.53 5.24 0.43 6.63e-7 Schizophrenia; TGCT cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.42e-9 Bipolar disorder; TGCT cis rs9359856 0.623 rs7742602 chr6:90327385 A/G cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.88 -0.4 3.15e-6 Bipolar disorder; TGCT cis rs1563304 1 rs1563304 chr17:44874453 C/T cg17911788 chr17:44343683 NA -0.56 -5.02 -0.41 1.76e-6 Neuroticism; TGCT cis rs7017697 0.642 rs3927029 chr8:19681933 G/A cg03894339 chr8:19674705 INTS10 -0.61 -4.75 -0.39 5.58e-6 Breast cancer; TGCT cis rs35883536 0.609 rs1577513 chr1:101044402 C/A cg06223162 chr1:101003688 GPR88 0.42 7.84 0.58 1.77e-12 Monocyte count; TGCT cis rs3749237 0.555 rs2117939 chr3:49415179 C/A cg03060546 chr3:49711283 APEH 0.77 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs881375 0.702 rs3761847 chr9:123690239 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.37 0.43 3.76e-7 Rheumatoid arthritis; TGCT trans rs208515 0.525 rs12214310 chr6:66666308 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.9 9.56 0.65 1.46e-16 Exhaled nitric oxide levels; TGCT cis rs7666738 0.830 rs7691864 chr4:98971376 G/C cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7044106 0.734 rs12553070 chr9:123485266 C/T cg14255062 chr9:123606675 PSMD5;LOC253039 0.19 4.51 0.38 1.5e-5 Hip circumference adjusted for BMI; TGCT cis rs1008375 0.966 rs3775925 chr4:17588437 A/G cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1215050 0.740 rs783916 chr4:99026264 A/C cg17366294 chr4:99064904 C4orf37 -0.59 -6.35 -0.5 3.73e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7474896 0.537 rs2749586 chr10:38270214 G/C cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs7647973 1.000 rs10155014 chr3:49432321 C/T cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.58 -0.38 1.11e-5 Menarche (age at onset); TGCT cis rs36051895 0.623 rs10815148 chr9:5057284 T/A cg02405213 chr9:5042618 JAK2 -0.8 -10.54 -0.69 6.06e-19 Pediatric autoimmune diseases; TGCT cis rs9916302 0.861 rs11078896 chr17:37415544 C/T cg15445000 chr17:37608096 MED1 0.33 4.84 0.4 3.8e-6 Glomerular filtration rate (creatinine); TGCT cis rs597539 0.617 rs598353 chr11:68635770 C/A cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs367943 1.000 rs348952 chr5:112821990 G/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs1801251 0.778 rs2592115 chr2:233736349 C/T cg25237894 chr2:233734115 C2orf82 -0.29 -5.63 -0.45 1.14e-7 Coronary artery disease; TGCT cis rs17270561 0.779 rs12210620 chr6:25884785 T/C cg16482183 chr6:26056742 HIST1H1C 0.89 6.63 0.51 9.23e-10 Iron status biomarkers; TGCT cis rs10779751 0.690 rs28729193 chr1:11180151 T/C cg08854313 chr1:11322531 MTOR -0.82 -6.58 -0.51 1.17e-9 Body mass index; TGCT cis rs72945132 0.882 rs7943840 chr11:70228615 C/A cg00319359 chr11:70116639 PPFIA1 1.03 7.86 0.58 1.59e-12 Coronary artery disease; TGCT cis rs4730779 0.545 rs3808184 chr7:117214125 T/C cg10524701 chr7:117356490 CTTNBP2 0.23 4.87 0.4 3.4e-6 Waist circumference; TGCT cis rs9733 0.596 rs1336898 chr1:150665050 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs6570726 0.791 rs436156 chr6:145874873 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7091068 0.802 rs10786121 chr10:95419796 G/A cg20715218 chr10:95462985 C10orf4 0.55 5.16 0.42 9.49e-7 Urinary tract infection frequency; TGCT cis rs6582630 0.599 rs1589392 chr12:38418535 G/C cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs589448 0.867 rs623853 chr12:69753830 G/A cg11871910 chr12:69753446 YEATS4 0.87 10.07 0.67 8.72e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs6534347 0.573 rs2221903 chr4:123538912 C/T cg10583651 chr4:123538969 IL21 -0.31 -4.51 -0.38 1.49e-5 Type 1 diabetes; TGCT cis rs7918232 0.882 rs2149413 chr10:27430311 C/T cg14442939 chr10:27389572 ANKRD26 -0.72 -5.35 -0.43 4.16e-7 Breast cancer; TGCT trans rs9650657 0.515 rs6601560 chr8:10950866 T/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.0 -0.53 1.45e-10 Neuroticism; TGCT cis rs10791097 0.720 rs6590518 chr11:130733530 C/T cg12179176 chr11:130786555 SNX19 0.83 10.11 0.67 6.98e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7666738 0.830 rs28515641 chr4:98726419 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2562152 0.706 rs216596 chr16:105320 A/G cg08083976 chr16:432219 LOC100134368;TMEM8A -0.65 -4.88 -0.4 3.25e-6 Glioblastoma; TGCT cis rs1062177 1.000 rs2964578 chr5:151147198 T/A cg00977110 chr5:151150581 G3BP1 0.41 4.62 0.38 9.52e-6 Preschool internalizing problems; TGCT cis rs4975616 0.710 rs27996 chr5:1345474 A/G cg07493874 chr5:1342172 CLPTM1L -0.25 -6.07 -0.48 1.45e-8 Lung cancer; TGCT cis rs763014 0.898 rs916416 chr16:632198 T/A cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs631288 0.793 rs1530337 chr1:146683319 C/A cg25205988 chr1:146714368 CHD1L 1.33 5.39 0.44 3.4e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs7100689 0.646 rs11202721 chr10:82135762 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs7216064 0.954 rs8079291 chr17:65887622 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4689388 0.929 rs1046320 chr4:6304344 C/T cg00701064 chr4:6280414 WFS1 0.41 5.24 0.43 6.7e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs17221829 0.733 rs11018725 chr11:89413251 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 1.96e-5 Anxiety in major depressive disorder; TGCT cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg06640241 chr16:89574553 SPG7 0.79 8.98 0.63 3.73e-15 Multiple myeloma (IgH translocation); TGCT cis rs11148252 0.774 rs6561666 chr13:52930045 A/G cg00495681 chr13:53174319 NA 0.57 5.58 0.45 1.45e-7 Lewy body disease; TGCT trans rs1814175 0.645 rs10839456 chr11:49964093 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs8084125 0.832 rs62105174 chr18:74948324 G/A cg07390210 chr18:74961196 GALR1 0.36 4.46 0.37 1.85e-5 Obesity-related traits; TGCT cis rs6500602 0.702 rs3761680 chr16:4524060 C/A cg08645402 chr16:4508243 NA 0.18 4.97 0.41 2.21e-6 Schizophrenia; TGCT cis rs2721195 0.845 rs4244611 chr8:145739924 G/A cg17328964 chr8:145687451 CYHR1 -0.44 -6.22 -0.49 6.83e-9 Age at first birth; TGCT cis rs12478296 1.000 rs73007138 chr2:243007041 C/T cg06360820 chr2:242988706 NA -0.88 -5.78 -0.46 5.76e-8 Obesity-related traits; TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT cis rs5757676 0.858 rs6001585 chr22:39812986 G/T cg05872129 chr22:39784769 NA -0.92 -7.75 -0.57 2.88e-12 IgG glycosylation; TGCT cis rs9308731 0.644 rs60286362 chr2:111877493 G/C cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.1e-9 Chronic lymphocytic leukemia; TGCT cis rs2730260 0.537 rs3793224 chr7:158876573 G/A cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg07157834 chr1:205819609 PM20D1 0.45 7.36 0.55 2.21e-11 Menarche (age at onset); TGCT cis rs2832191 0.720 rs4643617 chr21:30485278 T/C cg24692254 chr21:30365293 RNF160 -0.94 -10.58 -0.69 4.78e-19 Dental caries; TGCT cis rs1577917 1.000 rs6936048 chr6:86702608 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT trans rs4824093 0.610 rs4824113 chr22:50284974 C/T cg09872104 chr7:134855509 C7orf49 -1.01 -8.43 -0.6 7.42e-14 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs79387448 0.745 rs6742433 chr2:103175360 C/T cg09003973 chr2:102972529 NA 0.97 6.32 0.49 4.33e-9 Gut microbiota (bacterial taxa); TGCT cis rs6952808 0.792 rs12537914 chr7:1948359 C/T cg22963979 chr7:1858916 MAD1L1 -0.35 -5.43 -0.44 2.9e-7 Bipolar disorder and schizophrenia; TGCT cis rs1580019 0.961 rs6949851 chr7:32493807 T/G cg06627557 chr7:32535165 LSM5;AVL9 0.77 7.07 0.54 1.01e-10 Cognitive ability; TGCT cis rs4372836 0.681 rs6419696 chr2:29010339 G/A cg09522027 chr2:28974177 PPP1CB -0.69 -7.27 -0.55 3.54e-11 Body mass index; TGCT cis rs12188164 0.686 rs56279338 chr5:416118 G/A cg26850624 chr5:429559 AHRR -0.22 -5.08 -0.41 1.36e-6 Cystic fibrosis severity; TGCT cis rs11096990 0.551 rs2060005 chr4:39162521 A/G cg20847110 chr4:39482781 LOC401127 0.17 4.86 0.4 3.49e-6 Cognitive function; TGCT cis rs3862435 0.571 rs2589950 chr15:90957179 C/T cg14166756 chr15:90894880 ZNF774 -0.29 -4.76 -0.39 5.19e-6 Response to exercise (triglyceride level interaction); TGCT cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg25036284 chr2:26402008 FAM59B -0.61 -4.9 -0.4 2.92e-6 Gut microbiome composition (summer); TGCT cis rs1799899 0.826 rs1800277 chr3:133466155 A/G cg18342939 chr3:134203408 ANAPC13;CEP63 -0.48 -4.91 -0.4 2.85e-6 Alcohol consumption (transferrin glycosylation); TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg10150615 chr22:24372951 LOC391322 -0.97 -12.67 -0.75 4.14e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7829975 0.508 rs4841006 chr8:8501474 T/C cg15556689 chr8:8085844 FLJ10661 -0.54 -5.14 -0.42 1.04e-6 Mood instability; TGCT cis rs6840360 0.809 rs6846809 chr4:152730201 A/G cg22705602 chr4:152727874 NA 0.27 4.82 0.4 4.09e-6 Intelligence (multi-trait analysis); TGCT cis rs769267 0.930 rs747050 chr19:19584987 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.71 5.95 0.47 2.57e-8 Tonsillectomy; TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg22166914 chr1:53195759 ZYG11B 0.3 4.88 0.4 3.23e-6 Monocyte count; TGCT cis rs3803170 0.513 rs4766573 chr12:111830809 C/A cg10833066 chr12:111807467 FAM109A 0.36 5.41 0.44 3.09e-7 Mean corpuscular hemoglobin; TGCT cis rs736408 0.812 rs2239699 chr3:52827915 C/T cg07507251 chr3:52567010 NT5DC2 0.41 5.46 0.44 2.46e-7 Bipolar disorder; TGCT cis rs35306767 0.623 rs72760943 chr10:1143104 G/A cg20503657 chr10:835505 NA 0.51 5.41 0.44 3.18e-7 Eosinophil percentage of granulocytes; TGCT cis rs7147624 0.572 rs72714498 chr14:66037734 C/T cg03016385 chr14:66212404 NA 0.59 6.26 0.49 5.7e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs11648796 0.721 rs3169403 chr16:769247 G/A cg07343612 chr16:622815 PIGQ -0.38 -5.24 -0.43 6.6e-7 Height; TGCT cis rs78487399 0.731 rs6722104 chr2:43752346 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.02 -0.41 1.75e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10411936 0.924 rs8110761 chr19:16501005 A/G cg14704714 chr19:15740395 CYP4F8 0.25 4.45 0.37 1.86e-5 White blood cell count;Multiple sclerosis; TGCT cis rs2594989 0.806 rs2606746 chr3:11375120 A/G cg00170343 chr3:11313890 ATG7 0.64 5.14 0.42 1.05e-6 Circulating chemerin levels; TGCT cis rs2486288 0.656 rs62026703 chr15:45569929 G/T cg14582100 chr15:45693742 SPATA5L1 -0.43 -4.86 -0.4 3.48e-6 Glomerular filtration rate; TGCT cis rs35883536 0.609 rs12747197 chr1:101036831 A/C cg06223162 chr1:101003688 GPR88 -0.42 -8.0 -0.58 7.38e-13 Monocyte count; TGCT cis rs9611565 0.500 rs2011053 chr22:42121278 G/A cg17554472 chr22:41940697 POLR3H 0.45 4.84 0.4 3.72e-6 Vitiligo; TGCT cis rs4711350 0.765 rs2395446 chr6:33743264 C/T cg18005901 chr6:33739558 LEMD2 -0.6 -6.9 -0.53 2.42e-10 Schizophrenia; TGCT cis rs2932538 0.922 rs2273369 chr1:113072477 A/G cg22162597 chr1:113214053 CAPZA1 0.28 5.98 0.47 2.26e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT trans rs1814175 0.587 rs7937757 chr11:49978342 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs7267979 1.000 rs6037105 chr20:25374199 C/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12477438 1.000 rs12053372 chr2:99810055 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.75 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs56309584 0.715 rs77224069 chr17:8124268 G/C cg08322244 chr17:8066669 VAMP2 -0.57 -5.26 -0.43 6.21e-7 Initial pursuit acceleration; TGCT cis rs2242116 0.734 rs4683294 chr3:46979013 C/G cg27129171 chr3:47204927 SETD2 -0.64 -6.41 -0.5 2.76e-9 Birth weight; TGCT cis rs9368481 0.729 rs10946881 chr6:26914611 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 0.47 5.0 0.41 1.89e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2235642 0.821 rs2281236 chr16:1603576 G/A cg07341220 chr16:1583899 IFT140;TMEM204 -0.29 -4.56 -0.38 1.23e-5 Coronary artery disease; TGCT cis rs2836974 0.644 rs7281853 chr21:40693490 A/G cg06238570 chr21:40685208 BRWD1 -0.78 -8.67 -0.61 2.02e-14 Cognitive function; TGCT cis rs12681287 0.571 rs10097450 chr8:87358677 G/A cg27223183 chr8:87520930 FAM82B 0.9 6.71 0.52 6.12e-10 Caudate activity during reward; TGCT cis rs317689 0.690 rs618470 chr12:69672060 A/G cg14784868 chr12:69753453 YEATS4 0.53 4.51 0.38 1.48e-5 Response to diuretic therapy; TGCT cis rs7949030 0.626 rs35587183 chr11:62318656 C/T cg22862634 chr11:62369728 EML3;MTA2 0.62 6.29 0.49 4.86e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9467773 0.844 rs2393669 chr6:26503873 C/T cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT trans rs208520 0.690 rs851458 chr6:66813279 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.61 -0.69 4.11e-19 Exhaled nitric oxide output; TGCT cis rs6671200 0.607 rs10874908 chr1:95704151 C/G cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs10791323 0.604 rs2250025 chr11:133710914 G/A cg15485101 chr11:133734466 NA 0.39 5.12 0.42 1.15e-6 Childhood ear infection; TGCT cis rs4383453 0.539 rs2009176 chr3:123100976 C/T cg04890266 chr3:123102914 ADCY5 -0.5 -8.19 -0.59 2.68e-13 Gestational age at birth (maternal effect); TGCT cis rs3008870 0.755 rs10789219 chr1:67417742 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.82 8.49 0.61 5.37e-14 Lymphocyte percentage of white cells; TGCT cis rs28595532 1.000 rs115706377 chr4:119628481 G/A cg21605333 chr4:119757512 SEC24D 1.33 8.02 0.58 6.93e-13 Cannabis dependence symptom count; TGCT cis rs189218934 1 rs189218934 chr15:78903987 T/C cg24631222 chr15:78858424 CHRNA5 -0.88 -6.66 -0.51 7.79e-10 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs28595532 0.920 rs115085630 chr4:119741765 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs8070740 0.617 rs1058115 chr17:5323269 A/G cg25236894 chr17:5323110 RPAIN;NUP88 -0.64 -6.33 -0.49 4.08e-9 Menopause (age at onset); TGCT cis rs2153535 0.580 rs1832100 chr6:8446956 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs17376456 0.825 rs10052662 chr5:93271385 A/G cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs394563 0.591 rs237026 chr6:149720681 G/A cg16235748 chr6:149772707 ZC3H12D -0.44 -5.06 -0.41 1.46e-6 Dupuytren's disease; TGCT cis rs68170813 0.559 rs12540475 chr7:106886295 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs2549003 0.933 rs3846731 chr5:131814264 T/C cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs11122272 0.668 rs2472261 chr1:231505701 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -6.93 -0.53 1.99e-10 Hemoglobin concentration; TGCT cis rs1030877 0.960 rs3792047 chr2:105901553 A/G cg02079111 chr2:105885981 TGFBRAP1 -0.17 -4.74 -0.39 5.87e-6 Obesity-related traits; TGCT cis rs28595532 0.844 rs115573749 chr4:119756848 T/A cg21605333 chr4:119757512 SEC24D 1.62 7.73 0.57 3.22e-12 Cannabis dependence symptom count; TGCT cis rs2688608 0.592 rs7076585 chr10:75503692 T/C cg19442545 chr10:75533431 FUT11 -0.36 -5.66 -0.45 9.76e-8 Inflammatory bowel disease; TGCT cis rs9325144 0.671 rs12818797 chr12:39019409 A/G cg10518543 chr12:38710700 ALG10B -0.5 -4.8 -0.4 4.45e-6 Morning vs. evening chronotype; TGCT cis rs5769765 0.818 rs138850 chr22:50193337 C/T cg22709217 chr22:50311962 ALG12;CRELD2 0.88 8.8 0.62 9.76e-15 Schizophrenia; TGCT cis rs6450176 1.000 rs6450175 chr5:53297824 C/T ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.12 -0.42 1.15e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs6714788 0.503 rs11681737 chr2:100679024 T/C cg07810366 chr2:100720526 AFF3 -0.38 -5.2 -0.42 7.95e-7 Intelligence (multi-trait analysis); TGCT cis rs12620999 0.887 rs10929214 chr2:238037436 C/G cg23555395 chr2:238036564 NA -0.3 -5.19 -0.42 8.25e-7 Systemic lupus erythematosus; TGCT cis rs5769707 0.967 rs739248 chr22:50025205 T/C cg10356904 chr22:49881777 NA -0.22 -4.52 -0.38 1.4e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs36051895 0.659 rs7045342 chr9:5183892 T/C cg02405213 chr9:5042618 JAK2 -0.69 -8.71 -0.62 1.6e-14 Pediatric autoimmune diseases; TGCT cis rs4808199 0.948 rs1859287 chr19:19422187 T/C cg03709012 chr19:19516395 GATAD2A 0.81 6.55 0.51 1.4e-9 Nonalcoholic fatty liver disease; TGCT cis rs4273100 0.607 rs1043809 chr17:19239432 C/T cg03910582 chr17:19030146 GRAPL -0.51 -6.21 -0.49 7.47e-9 Schizophrenia; TGCT cis rs2841233 0.520 rs77494727 chr14:105348018 A/G cg03469805 chr14:105330648 KIAA0284 -0.45 -5.0 -0.41 1.93e-6 IgG glycosylation; TGCT cis rs941408 1.000 rs1624295 chr19:2792034 G/A cg06609049 chr19:2785107 THOP1 0.77 7.55 0.56 8.09e-12 Total cholesterol levels; TGCT trans rs1908814 0.504 rs7830734 chr8:11795639 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.72e-11 Neuroticism; TGCT cis rs4073582 0.595 rs2508657 chr11:66043898 G/A cg16950941 chr11:66035639 RAB1B 0.58 5.44 0.44 2.67e-7 Gout; TGCT cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg06634786 chr22:41940651 POLR3H 0.89 8.81 0.62 9.46e-15 Vitiligo; TGCT cis rs2980439 0.783 rs2948305 chr8:8098577 G/A cg08975724 chr8:8085496 FLJ10661 0.56 5.1 0.42 1.24e-6 Neuroticism; TGCT cis rs6882046 0.513 rs454214 chr5:88003403 A/G cg24804195 chr5:87968844 LOC645323 0.58 5.64 0.45 1.1e-7 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2836974 0.897 rs2026265 chr21:40595517 G/A cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.67e-16 Cognitive function; TGCT cis rs6490294 0.799 rs73424286 chr12:112327142 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs12510870 0.634 rs4618279 chr4:74382503 A/G cg05868023 chr4:75230803 EREG 0.56 5.07 0.41 1.42e-6 Iris color (b* coordinate); TGCT cis rs6540559 0.673 rs2357230 chr1:210019498 G/A cg21951975 chr1:209979733 IRF6 0.64 4.82 0.4 4.12e-6 Cleft lip with or without cleft palate; TGCT trans rs561341 0.700 rs8079471 chr17:30218317 A/G cg20587970 chr11:113659929 NA -0.59 -8.85 -0.62 7.64e-15 Hip circumference adjusted for BMI; TGCT cis rs7822232 0.908 rs56138570 chr8:145142206 G/A cg14631276 chr8:145163102 KIAA1875 -0.56 -5.05 -0.41 1.55e-6 Blood metabolite levels; TGCT cis rs2153535 0.580 rs2184584 chr6:8468407 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs3820928 0.874 rs7563644 chr2:227846932 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.59 -0.38 1.05e-5 Pulmonary function; TGCT cis rs2871473 1.000 rs2871473 chr2:103107280 A/C cg09003973 chr2:102972529 NA 0.64 4.52 0.38 1.4e-5 Blood protein levels; TGCT cis rs6121246 0.954 rs6121245 chr20:30432060 G/A cg13852791 chr20:30311386 BCL2L1 0.76 5.67 0.45 9.7e-8 Mean corpuscular hemoglobin; TGCT cis rs826838 0.900 rs11169301 chr12:39128497 C/A cg26384229 chr12:38710491 ALG10B 0.95 8.73 0.62 1.41e-14 Heart rate; TGCT cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs4680 0.737 rs4646312 chr22:19948337 C/T cg23601416 chr22:19950040 COMT 0.38 5.09 0.42 1.29e-6 Blood metabolite levels; TGCT cis rs7772486 0.641 rs2253757 chr6:146199686 C/T cg05347473 chr6:146136440 FBXO30 0.67 6.27 0.49 5.48e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs933688 1.000 rs61612071 chr5:90741470 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.47 0.61 6.09e-14 Smoking behavior; TGCT cis rs1862618 0.671 rs2591966 chr5:56233688 T/G cg20203395 chr5:56204925 C5orf35 0.51 4.74 0.39 5.72e-6 Initial pursuit acceleration; TGCT cis rs6867032 1.000 rs28392808 chr5:2013477 A/G cg26168224 chr5:2018326 NA 0.46 8.36 0.6 1.08e-13 Gut microbiome composition (winter); TGCT cis rs910316 0.967 rs2268619 chr14:75640354 C/G cg23033748 chr14:75592666 NEK9 -0.28 -4.64 -0.38 8.72e-6 Height; TGCT cis rs317689 0.680 rs315140 chr12:69790780 A/T cg20891283 chr12:69753455 YEATS4 0.55 4.62 0.38 9.53e-6 Response to diuretic therapy; TGCT cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg09904177 chr6:26538194 HMGN4 0.63 5.71 0.46 7.78e-8 Intelligence (multi-trait analysis); TGCT cis rs12893668 0.663 rs12889731 chr14:104087482 C/T cg26031613 chr14:104095156 KLC1 -0.55 -4.64 -0.38 8.81e-6 Reticulocyte count; TGCT cis rs7582180 0.606 rs10174145 chr2:100932488 T/C cg14675211 chr2:100938903 LONRF2 0.53 5.24 0.43 6.82e-7 Intelligence (multi-trait analysis); TGCT cis rs12908161 0.959 rs17598603 chr15:85200211 C/G cg17173187 chr15:85201210 NMB -0.57 -6.53 -0.51 1.52e-9 Schizophrenia; TGCT cis rs2172802 0.576 rs7656189 chr4:62411676 A/G cg04118610 chr4:62707027 LPHN3 -0.4 -4.91 -0.4 2.86e-6 Partial epilepsies; TGCT cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg13944838 chr5:179740914 GFPT2 -0.4 -6.32 -0.49 4.35e-9 Height; TGCT trans rs3780486 0.846 rs7036812 chr9:33143822 T/C cg04842962 chr6:43655489 MRPS18A 1.21 14.37 0.79 3.68e-28 IgG glycosylation; TGCT cis rs4478858 0.684 rs10798837 chr1:31719340 C/T cg00250761 chr1:31883323 NA -0.26 -4.74 -0.39 5.75e-6 Alcohol dependence; TGCT cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.15e-6 Blood metabolite levels; TGCT cis rs1451375 0.755 rs3829897 chr7:50629764 G/T cg18232548 chr7:50535776 DDC 0.44 7.03 0.53 1.22e-10 Malaria; TGCT cis rs9911578 0.935 rs6503878 chr17:56884581 T/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs922182 0.599 rs34409256 chr15:64270314 G/T cg02919090 chr15:64263738 DAPK2 -0.29 -5.21 -0.42 7.69e-7 Blood protein levels; TGCT cis rs2617583 0.530 rs1478435 chr5:1454612 T/C cg13982541 chr5:1466431 LPCAT1 0.2 4.86 0.4 3.45e-6 Breast cancer; TGCT cis rs17376456 0.569 rs1349711 chr5:93179032 C/T cg25358565 chr5:93447407 FAM172A -0.84 -6.67 -0.51 7.58e-10 Diabetic retinopathy; TGCT cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.53 0.44 1.79e-7 Height; TGCT cis rs4466137 0.953 rs1420654 chr5:82975793 G/A cg16102102 chr5:83017553 HAPLN1 -0.93 -10.85 -0.7 1.06e-19 Prostate cancer; TGCT cis rs2370759 1.000 rs2370759 chr10:32634972 G/A cg01819863 chr10:32635814 EPC1 1.0 9.52 0.65 1.8e-16 Sexual dysfunction (female); TGCT cis rs319204 0.851 rs319190 chr5:146270241 A/G cg25021259 chr5:146258546 PPP2R2B 0.35 4.49 0.37 1.63e-5 Schizophrenia; TGCT cis rs57221529 0.766 rs12519469 chr5:581772 A/G cg16624210 chr5:671434 TPPP 0.37 4.44 0.37 1.99e-5 Lung disease severity in cystic fibrosis; TGCT cis rs1008375 0.966 rs12509962 chr4:17680292 G/A cg10189774 chr4:17578691 LAP3 0.52 4.89 0.4 3.1e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7726839 0.574 rs72707007 chr5:661856 T/C cg11887960 chr12:57824829 NA 1.12 9.54 0.65 1.68e-16 Obesity-related traits; TGCT cis rs7267979 0.966 rs2424714 chr20:25418681 T/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.99 -10.88 -0.7 8.97e-20 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs11578119 0.866 rs10919379 chr1:170354577 T/C cg09767346 chr1:170501363 GORAB 0.61 4.61 0.38 9.8e-6 Male-pattern baldness; TGCT cis rs6582630 0.513 rs11181246 chr12:38302670 C/T cg26384229 chr12:38710491 ALG10B 0.82 7.14 0.54 6.78e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7681440 0.647 rs1442136 chr4:90819026 C/T cg20003494 chr4:90757398 SNCA 0.53 4.7 0.39 6.88e-6 Dementia with Lewy bodies; TGCT cis rs1971762 0.527 rs9737721 chr12:54074696 A/T cg16917193 chr12:54089295 NA 1.33 16.62 0.83 2.36e-33 Height; TGCT cis rs112591243 0.570 rs4819254 chr21:47887462 T/A cg10657630 chr21:48055338 PRMT2 1.06 5.21 0.42 7.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg04267008 chr7:1944627 MAD1L1 0.36 4.59 0.38 1.05e-5 Bipolar disorder and schizophrenia; TGCT cis rs911555 0.815 rs2756118 chr14:103992473 C/T cg12935359 chr14:103987150 CKB 0.38 5.37 0.43 3.7e-7 Intelligence (multi-trait analysis); TGCT cis rs9328448 1.000 rs7744601 chr6:7988910 T/C cg13863638 chr6:7199401 RREB1 0.19 4.46 0.37 1.79e-5 Coronary artery calcification; TGCT cis rs79349575 0.783 rs62075820 chr17:46983171 G/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs76419734 0.510 rs7659526 chr4:106621643 T/C cg24545054 chr4:106630052 GSTCD;INTS12 0.71 4.66 0.39 7.95e-6 Post bronchodilator FEV1; TGCT cis rs6570726 0.967 rs373704 chr6:145860618 C/A cg05347473 chr6:146136440 FBXO30 0.5 4.46 0.37 1.82e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs12464483 0.591 rs72800120 chr2:30897122 G/A cg12454169 chr2:30669597 LCLAT1 0.52 5.58 0.45 1.42e-7 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs1005224 0.889 rs12717566 chr14:76147507 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.66 -5.8 -0.46 5.13e-8 Large artery stroke; TGCT cis rs3820928 0.874 rs13423714 chr2:227896652 C/G cg11843606 chr2:227700838 RHBDD1 0.56 5.04 0.41 1.63e-6 Pulmonary function; TGCT cis rs3772130 0.603 rs35489993 chr3:121411876 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.14e-6 Cognitive performance; TGCT cis rs7267979 0.816 rs404775 chr20:25481117 A/G cg14121845 chr20:25566513 NINL 0.46 4.76 0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9443645 0.901 rs1890229 chr6:79695029 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs1670533 0.872 rs935969 chr4:1062588 A/G cg27284194 chr4:1044797 NA 0.7 6.09 0.48 1.28e-8 Recombination rate (females); TGCT cis rs9341808 0.644 rs59371711 chr6:80942027 G/T cg08355045 chr6:80787529 NA -0.28 -4.52 -0.38 1.45e-5 Sitting height ratio; TGCT cis rs1475911 1.000 rs34421316 chr21:43513989 C/T cg19766460 chr21:43528205 UMODL1;C21orf128 0.52 6.85 0.52 3e-10 IgG glycosylation; TGCT cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 3.03e-27 Menopause (age at onset); TGCT cis rs2304725 0.526 rs2600091 chr3:10826905 C/A cg15914589 chr3:10206523 IRAK2 0.46 4.47 0.37 1.74e-5 Pulmonary function in asthmatics; TGCT cis rs6121246 0.567 rs6060263 chr20:30193110 T/C cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs8177253 0.965 rs7638018 chr3:133495461 C/T cg20276088 chr3:133502917 NA 0.24 5.26 0.43 6.13e-7 Iron status biomarkers; TGCT cis rs6598955 0.502 rs6683157 chr1:26545865 G/A cg04990556 chr1:26633338 UBXN11 0.8 7.36 0.55 2.19e-11 Obesity-related traits; TGCT cis rs9796 0.662 rs8033435 chr15:41436479 C/T cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.86 -0.52 2.97e-10 Menopause (age at onset); TGCT cis rs208515 0.525 rs12204706 chr6:66669930 A/G cg07460842 chr6:66804631 NA -0.86 -8.95 -0.63 4.31e-15 Exhaled nitric oxide levels; TGCT cis rs9303401 0.659 rs66514313 chr17:56714057 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs3008870 1.000 rs975451 chr1:67480060 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.08 11.47 0.72 3.32e-21 Lymphocyte percentage of white cells; TGCT cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs1466788 1.000 rs3754439 chr1:110615094 A/G cg11787288 chr1:111506544 C1orf103 0.49 4.5 0.38 1.51e-5 Blood metabolite levels; TGCT cis rs6669384 0.737 rs882198 chr1:208036509 A/G cg22525895 chr1:207977042 MIR29B2 0.37 5.08 0.42 1.32e-6 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs1997103 0.906 rs6593231 chr7:55402914 T/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs3806843 1.000 rs1030164 chr5:140185272 A/G cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2562456 0.833 rs2562416 chr19:21613411 A/G cg25650185 chr19:21324782 ZNF431 -0.56 -4.45 -0.37 1.88e-5 Pain; TGCT cis rs789852 0.867 rs1675938 chr3:194327370 T/A cg18000598 chr3:194342907 TMEM44 -0.81 -5.19 -0.42 8.35e-7 QT interval; TGCT cis rs7412746 0.658 rs17660092 chr1:150797748 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.13 0.42 1.1e-6 Melanoma; TGCT cis rs7819412 0.668 rs2409714 chr8:11010118 A/G cg21775007 chr8:11205619 TDH -0.61 -5.97 -0.47 2.3e-8 Triglycerides; TGCT cis rs7104764 0.507 rs6598056 chr11:252283 A/G cg18336825 chr11:236787 PSMD13;SIRT3 -0.71 -5.37 -0.43 3.67e-7 Menarche (age at onset); TGCT cis rs769267 0.965 rs4808937 chr19:19398005 A/G cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs7824557 0.564 rs2572400 chr8:11234367 T/G cg21775007 chr8:11205619 TDH -0.64 -6.27 -0.49 5.48e-9 Retinal vascular caliber; TGCT cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs514406 1.000 rs514406 chr1:53330458 A/G cg24675658 chr1:53192096 ZYG11B -0.75 -6.34 -0.49 3.84e-9 Monocyte count; TGCT cis rs4285028 0.747 rs58367397 chr3:121451700 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs1514658 0.903 rs13124454 chr4:119279431 G/A cg21605333 chr4:119757512 SEC24D -0.5 -4.5 -0.37 1.56e-5 Congenital heart disease (maternal effect); TGCT cis rs4808199 0.948 rs757000 chr19:19448301 A/G cg03709012 chr19:19516395 GATAD2A 0.81 6.32 0.49 4.32e-9 Nonalcoholic fatty liver disease; TGCT cis rs28735056 0.967 rs56328473 chr18:77636101 C/T cg20368463 chr18:77673604 PQLC1 -0.44 -5.46 -0.44 2.44e-7 Schizophrenia; TGCT cis rs6754311 0.593 rs2034276 chr2:136422171 A/T cg07169764 chr2:136633963 MCM6 0.65 5.87 0.47 3.74e-8 Mosquito bite size; TGCT cis rs5769765 0.955 rs4075330 chr22:50303249 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.17 -11.54 -0.72 2.25e-21 Schizophrenia; TGCT cis rs1903068 1.000 rs1903068 chr4:56008477 A/G cg09978860 chr4:56023921 NA 0.58 6.61 0.51 1.02e-9 Endometriosis; TGCT cis rs7119038 0.818 rs715412 chr11:118684610 G/A cg19308663 chr11:118741387 NA 0.29 5.76 0.46 6.25e-8 Sjögren's syndrome; TGCT cis rs2456568 0.802 rs1506656 chr11:93639813 G/A cg16099599 chr11:93583650 C11orf90 -0.39 -4.77 -0.39 5.02e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs11578119 0.933 rs1412890 chr1:170413406 C/T cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.66e-8 Male-pattern baldness; TGCT cis rs10507380 0.766 rs78172194 chr13:27919689 A/C cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs11252926 0.598 rs4881256 chr10:453831 T/A cg20256804 chr10:444983 DIP2C -0.21 -4.45 -0.37 1.9e-5 Psychosis in Alzheimer's disease; TGCT cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg10802521 chr3:52805072 NEK4 -0.74 -9.21 -0.64 1.02e-15 Electroencephalogram traits; TGCT cis rs57221529 0.766 rs72706610 chr5:561111 G/A cg09021430 chr5:549028 NA -0.4 -5.48 -0.44 2.24e-7 Lung disease severity in cystic fibrosis; TGCT cis rs1372520 0.684 rs2572318 chr4:90718719 C/T cg15133208 chr4:90757351 SNCA -0.5 -5.09 -0.42 1.28e-6 Neuroticism; TGCT cis rs9467773 0.836 rs1624440 chr6:26433329 G/A cg09904177 chr6:26538194 HMGN4 -0.51 -4.68 -0.39 7.5e-6 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.569 rs4785708 chr16:89796569 C/T cg27121462 chr16:89883253 FANCA -0.5 -4.67 -0.39 7.64e-6 Vitiligo; TGCT cis rs9913156 0.793 rs9916135 chr17:4568115 A/C cg23387401 chr17:4582204 PELP1 -0.31 -4.63 -0.38 8.97e-6 Lymphocyte counts; TGCT cis rs4455778 0.519 rs34062689 chr7:49035022 G/T cg26309511 chr7:48887640 NA 0.52 6.9 0.53 2.36e-10 Lung cancer in never smokers; TGCT cis rs10114408 0.879 rs10821244 chr9:96638449 A/G cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9549367 0.826 rs9549713 chr13:113905308 G/T cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs9611565 0.921 rs2143695 chr22:41728620 A/G cg03806693 chr22:41940476 POLR3H -0.83 -8.68 -0.61 1.93e-14 Vitiligo; TGCT cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg18305652 chr10:134549665 INPP5A 0.35 5.93 0.47 2.87e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9486715 0.867 rs6568428 chr6:96903604 A/G cg06623918 chr6:96969491 KIAA0776 1.11 16.47 0.83 5.28e-33 Headache; TGCT cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg00684032 chr4:1343700 KIAA1530 -0.22 -4.72 -0.39 6.18e-6 Obesity-related traits; TGCT cis rs896854 0.812 rs2340586 chr8:95969261 G/A cg16049864 chr8:95962084 TP53INP1 -0.75 -10.28 -0.68 2.7e-18 Type 2 diabetes; TGCT cis rs7568458 0.870 rs1972297 chr2:85808573 T/C cg17127132 chr2:85788382 GGCX 0.67 6.24 0.49 6.43e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4969178 0.560 rs4969182 chr17:76393030 T/C cg05887092 chr17:76393375 PGS1 0.21 4.49 0.37 1.58e-5 HDL cholesterol levels; TGCT cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg13683864 chr3:40499215 RPL14 -1.12 -11.9 -0.73 2.94e-22 Renal cell carcinoma; TGCT cis rs7584330 0.666 rs7600317 chr2:238353513 C/T cg14458575 chr2:238380390 NA 0.53 7.82 0.57 1.99e-12 Prostate cancer; TGCT cis rs11098499 0.779 rs7674500 chr4:120303593 C/T cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs7267979 0.844 rs6083845 chr20:25388090 G/C cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT trans rs629535 0.783 rs658407 chr8:70035247 T/C cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg21724239 chr8:58056113 NA 0.47 5.1 0.42 1.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs3782455 1.000 rs75235459 chr12:114400776 C/T cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6433895 1.000 rs55900432 chr2:182017904 G/A cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT cis rs60843830 0.633 rs1078763 chr2:113763 A/G cg25945732 chr2:264204 ACP1;SH3YL1 -0.59 -5.32 -0.43 4.61e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs853679 0.546 rs200981 chr6:27833174 A/G cg08798685 chr6:27730294 NA -0.34 -4.69 -0.39 7.2e-6 Depression; TGCT cis rs2153535 0.580 rs9379222 chr6:8514788 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs34734847 1.000 rs10431385 chr12:121128882 T/C cg21892295 chr12:121157589 UNC119B -0.23 -5.49 -0.44 2.17e-7 Mean corpuscular volume; TGCT cis rs524281 0.861 rs1862005 chr11:65863402 T/C cg00563793 chr11:65837595 PACS1 0.55 4.62 0.38 9.44e-6 Electroencephalogram traits; TGCT cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.51e-14 Type 2 diabetes; TGCT cis rs611744 0.752 rs609197 chr8:109234035 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT trans rs208520 0.545 rs6899712 chr6:66749670 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.04 14.26 0.79 6.57e-28 Exhaled nitric oxide output; TGCT cis rs6456156 0.792 rs2039321 chr6:167516299 C/T cg07741184 chr6:167504864 NA 0.22 4.44 0.37 2e-5 Primary biliary cholangitis; TGCT cis rs12615966 1.000 rs17030308 chr2:105385872 T/C cg16465502 chr2:105461796 NA 0.78 5.03 0.41 1.66e-6 Pancreatic cancer; TGCT cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg27588902 chr6:42928151 GNMT -0.56 -6.93 -0.53 2.08e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9300255 0.602 rs1716177 chr12:123655457 C/T cg00376283 chr12:123451042 ABCB9 0.66 4.85 0.4 3.59e-6 Neutrophil percentage of white cells; TGCT cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg16414030 chr3:133502952 NA -0.5 -7.01 -0.53 1.39e-10 Iron status biomarkers; TGCT cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg23172400 chr8:95962367 TP53INP1 -0.4 -6.56 -0.51 1.33e-9 Type 2 diabetes; TGCT cis rs2013441 1.000 rs9905493 chr17:20188581 C/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs7098414 0.530 rs10749572 chr10:82136664 G/T cg01528321 chr10:82214614 TSPAN14 0.51 4.45 0.37 1.91e-5 Post bronchodilator FEV1; TGCT cis rs6089829 0.962 rs2277768 chr20:61666823 T/C cg18188782 chr20:61659543 NA 0.44 5.48 0.44 2.24e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs4642101 0.561 rs7638333 chr3:12806142 T/C cg04715183 chr3:11886989 C3orf31 -0.17 -4.44 -0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs2180341 0.618 rs4502958 chr6:127593113 G/A cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs1451375 1.000 rs2329342 chr7:50624971 A/G cg18232548 chr7:50535776 DDC -0.41 -6.34 -0.49 3.85e-9 Malaria; TGCT cis rs981844 0.826 rs4585278 chr4:154684145 A/G cg14289246 chr4:154710475 SFRP2 1.06 9.98 0.67 1.4e-17 Response to statins (LDL cholesterol change); TGCT cis rs3796352 1.000 rs35737577 chr3:53002557 G/C cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1552244 0.882 rs68080705 chr3:10025743 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs2847281 0.761 rs8087237 chr18:12834359 G/T cg23598886 chr18:12777645 NA 0.39 4.69 0.39 6.96e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs506338 0.517 rs1207179 chr11:64450795 C/T cg19395706 chr11:64412079 NRXN2 0.5 6.05 0.48 1.58e-8 Body mass index;Urate levels; TGCT cis rs11105298 0.891 rs10858852 chr12:89833338 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6088580 0.634 rs6088508 chr20:33060081 A/G cg08999081 chr20:33150536 PIGU 0.29 5.66 0.45 9.97e-8 Glomerular filtration rate (creatinine); TGCT cis rs763014 1.000 rs7205409 chr16:642610 A/G cg27436995 chr16:743998 FBXL16 -0.48 -5.09 -0.42 1.29e-6 Height; TGCT cis rs7104764 1.000 rs1128322 chr11:244197 C/T cg18336825 chr11:236787 PSMD13;SIRT3 -1.07 -11.19 -0.71 1.61e-20 Menarche (age at onset); TGCT cis rs10489202 0.634 rs11582396 chr1:168077636 C/T cg24449463 chr1:168025552 DCAF6 -0.49 -5.06 -0.41 1.49e-6 Schizophrenia; TGCT cis rs7027203 1.000 rs34624092 chr9:96523092 G/A cg14396892 chr9:96623032 NA 0.23 4.6 0.38 1.03e-5 DNA methylation (variation); TGCT cis rs427394 0.735 rs416689 chr5:6740855 C/T cg10857441 chr5:6722123 POLS -0.32 -7.93 -0.58 1.08e-12 Menopause (age at onset); TGCT cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg12042659 chr19:58951599 ZNF132 0.53 4.64 0.38 8.82e-6 Uric acid clearance; TGCT cis rs950027 0.787 rs1153845 chr15:45724729 C/T cg26924012 chr15:45694286 SPATA5L1 -0.65 -7.04 -0.53 1.17e-10 Response to fenofibrate (adiponectin levels); TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT trans rs783396 0.685 rs60992370 chr6:107085676 A/C cg27564810 chr2:201635376 AOX2P 0.5 6.61 0.51 1e-9 Stroke; TGCT cis rs7226408 0.640 rs1968334 chr18:34343634 A/G cg06757138 chr18:34340585 FHOD3 0.29 4.97 0.41 2.14e-6 Obesity-related traits; TGCT cis rs1971762 0.762 rs7976793 chr12:54073069 G/T cg09709951 chr12:54017699 ATF7 0.35 5.38 0.44 3.52e-7 Height; TGCT cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg08439880 chr3:133502540 NA -0.27 -4.96 -0.41 2.32e-6 Iron status biomarkers; TGCT cis rs6495122 0.644 rs11630087 chr15:75261673 G/T cg09165964 chr15:75287851 SCAMP5 0.51 4.65 0.39 8.33e-6 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs236907 0.859 rs6656852 chr1:171752373 A/G cg20598894 chr1:171756153 METTL13 -0.19 -4.47 -0.37 1.72e-5 Mean platelet volume; TGCT trans rs4650994 0.544 rs11579513 chr1:178496092 T/C cg05059571 chr16:84539110 KIAA1609 -0.54 -11.23 -0.71 1.27e-20 HDL cholesterol levels;HDL cholesterol; TGCT trans rs1974653 0.672 rs9606256 chr22:20108500 G/A cg08822737 chr17:71088851 SLC39A11 -0.93 -7.65 -0.57 4.76e-12 Schizophrenia; TGCT cis rs1153858 0.887 rs28569043 chr15:45730926 A/T cg14582100 chr15:45693742 SPATA5L1 0.41 4.74 0.39 5.78e-6 Homoarginine levels; TGCT cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs7131987 0.903 rs67150462 chr12:29393325 T/C cg09582351 chr12:29534625 ERGIC2 -0.23 -4.54 -0.38 1.33e-5 QT interval; TGCT cis rs7647973 0.626 rs9824435 chr3:49674343 A/G cg03060546 chr3:49711283 APEH -0.64 -5.48 -0.44 2.25e-7 Menarche (age at onset); TGCT cis rs250677 0.687 rs2915809 chr5:148452111 A/T cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs9911578 0.934 rs8081967 chr17:57072701 T/C cg12560992 chr17:57184187 TRIM37 0.78 9.58 0.65 1.35e-16 Intelligence (multi-trait analysis); TGCT cis rs250677 0.687 rs36048 chr5:148441713 G/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs875971 1.000 rs2420591 chr7:65912381 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs7043114 0.525 rs7853859 chr9:95151377 A/G cg14631576 chr9:95140430 CENPP -0.26 -4.57 -0.38 1.14e-5 Height; TGCT cis rs7666738 0.830 rs17484890 chr4:99013778 T/C cg18180107 chr4:99064573 C4orf37 0.52 4.85 0.4 3.57e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6681544 0.760 rs1475395 chr1:82411947 C/T cg04226724 chr1:82268649 LPHN2 0.48 4.95 0.41 2.42e-6 Metabolite levels (X-11787); TGCT cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg09904177 chr6:26538194 HMGN4 0.67 6.32 0.49 4.25e-9 Intelligence (multi-trait analysis); TGCT cis rs12549025 0.530 rs34297248 chr8:23364378 G/A cg00472375 chr8:23315376 ENTPD4 0.62 5.37 0.43 3.72e-7 Reticulocyte fraction of red cells; TGCT cis rs189918 1 rs189918 chr1:6737212 T/C cg06778853 chr1:6672620 PHF13 -0.16 -4.46 -0.37 1.81e-5 Schizophrenia; TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg11965913 chr1:205819406 PM20D1 0.53 7.56 0.56 7.72e-12 Menarche (age at onset); TGCT cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg19318889 chr4:1322082 MAEA 0.27 6.56 0.51 1.28e-9 Longevity; TGCT cis rs4242434 0.699 rs878053 chr8:22483849 T/C cg03733263 chr8:22462867 KIAA1967 0.98 14.04 0.78 2.12e-27 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7824557 0.564 rs12550129 chr8:11233917 C/T cg21775007 chr8:11205619 TDH -0.67 -6.55 -0.51 1.35e-9 Retinal vascular caliber; TGCT cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg10047753 chr17:41438598 NA 0.91 8.44 0.6 6.86e-14 Menopause (age at onset); TGCT cis rs4455778 0.743 rs28867851 chr7:49097556 A/G cg26309511 chr7:48887640 NA 0.49 5.49 0.44 2.21e-7 Lung cancer in never smokers; TGCT cis rs854765 0.647 rs2955366 chr17:18024013 A/G cg04398451 chr17:18023971 MYO15A -0.39 -6.89 -0.53 2.53e-10 Total body bone mineral density; TGCT trans rs6089829 0.962 rs4586690 chr20:61658595 G/T cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467711 0.591 rs76091509 chr6:26706602 T/A cg12315302 chr6:26189340 HIST1H4D 1.24 4.96 0.41 2.3e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12220898 0.749 rs11101076 chr10:50486539 G/A cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs62244186 0.659 rs9819766 chr3:44520980 G/C cg15687855 chr3:44754131 ZNF502 -0.44 -5.18 -0.42 8.84e-7 Depressive symptoms; TGCT cis rs6570726 0.934 rs430003 chr6:145819506 C/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 1.000 rs9393728 chr6:26509330 C/G cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.560 rs2210798 chr6:8481522 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs3741404 0.560 rs12362602 chr11:63908660 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.76 -7.29 -0.55 3.23e-11 Platelet count; TGCT cis rs12497850 0.931 rs9840684 chr3:48893780 T/C cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT trans rs6089829 1.000 rs6089829 chr20:61669036 C/T cg13615516 chr5:77269221 NA -0.68 -8.11 -0.59 4.22e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs6450176 1.000 rs12521454 chr5:53297304 T/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.12 -0.42 1.15e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg02458000 chr6:26745757 NA 0.55 5.25 0.43 6.28e-7 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg04234412 chr22:24373322 LOC391322 -0.87 -10.27 -0.68 2.84e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs617219 0.710 rs6874525 chr5:78574237 C/T cg05890484 chr5:78407552 BHMT -0.34 -4.63 -0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7264396 0.790 rs6060565 chr20:34285442 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.96e-7 Total cholesterol levels; TGCT cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.61 -0.38 9.75e-6 Obesity-related traits; TGCT cis rs9911578 0.902 rs12948746 chr17:57071892 A/G cg12560992 chr17:57184187 TRIM37 0.78 9.61 0.65 1.1e-16 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg13695892 chr22:41940480 POLR3H -0.9 -9.05 -0.63 2.43e-15 Vitiligo; TGCT cis rs4665809 1.000 rs10170359 chr2:26272219 G/T cg27170947 chr2:26402098 FAM59B -0.4 -4.58 -0.38 1.1e-5 Gut microbiome composition (summer); TGCT cis rs79724016 1.000 rs11801716 chr1:42143899 C/T cg14093106 chr1:42503579 NA -0.66 -4.91 -0.4 2.78e-6 Breast cancer; TGCT cis rs56104184 0.775 rs17272707 chr19:49404535 T/G cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6121246 0.909 rs6060793 chr20:30288830 T/G cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs6840360 0.571 rs4696272 chr4:152528229 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs13396401 chr2:43701213 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.4 -0.44 3.21e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2463822 0.920 rs72923207 chr11:62117959 A/G cg06239285 chr11:62104954 ASRGL1 -0.94 -6.59 -0.51 1.15e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg17554472 chr22:41940697 POLR3H -0.47 -4.79 -0.4 4.68e-6 Vitiligo; TGCT cis rs2963155 0.590 rs258757 chr5:142620736 A/G cg17617527 chr5:142782415 NR3C1 -0.74 -5.9 -0.47 3.29e-8 Breast cancer; TGCT cis rs11249608 0.548 rs17078991 chr5:178459426 A/C cg01312482 chr5:178451176 ZNF879 -0.49 -4.85 -0.4 3.62e-6 Pubertal anthropometrics; TGCT cis rs6542838 0.611 rs1976766 chr2:99522754 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.46 -0.44 2.52e-7 Fear of minor pain; TGCT cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.11 -7.29 -0.55 3.13e-11 Gut microbiome composition (summer); TGCT cis rs9302001 0.883 rs1209118 chr13:95455315 C/G cg07483244 chr13:95358924 NA 0.35 4.47 0.37 1.72e-5 Panic disorder; TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs1218582 0.772 rs6656435 chr1:154876869 G/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs7809950 0.953 rs1468336 chr7:107208250 T/C cg23024343 chr7:107201750 COG5 0.35 5.32 0.43 4.76e-7 Coronary artery disease; TGCT cis rs4700695 0.719 rs27085 chr5:65435063 C/T cg21114390 chr5:65439923 SFRS12 0.85 7.52 0.56 9.85e-12 Facial morphology (factor 19); TGCT cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.73e-7 Menopause (age at onset); TGCT cis rs10509586 0.522 rs28719637 chr10:91689096 T/A cg25278353 chr10:91717815 NA 0.43 5.13 0.42 1.08e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs1943345 0.642 rs11233500 chr11:82881407 C/T cg07047830 chr11:82868014 PCF11 -0.52 -5.28 -0.43 5.68e-7 Obesity-related traits; TGCT cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg06634786 chr22:41940651 POLR3H 0.86 8.19 0.59 2.71e-13 Vitiligo; TGCT cis rs9916302 0.904 rs1077715 chr17:37683548 A/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.92 -0.4 2.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg23982607 chr1:1823379 GNB1 -0.56 -8.56 -0.61 3.65e-14 Body mass index; TGCT cis rs6920965 0.583 rs9388456 chr6:126147197 C/T cg05901451 chr6:126070800 HEY2 -0.62 -6.72 -0.52 5.97e-10 High light scatter reticulocyte count; TGCT cis rs4851266 1.000 rs2871344 chr2:100839430 A/G cg22139774 chr2:100720529 AFF3 -0.33 -5.03 -0.41 1.67e-6 Educational attainment; TGCT trans rs656319 0.629 rs10111315 chr8:9865588 G/A cg15556689 chr8:8085844 FLJ10661 -0.71 -6.62 -0.51 9.63e-10 Myopia (pathological); TGCT cis rs17376456 0.932 rs3940842 chr5:93534858 C/A cg25358565 chr5:93447407 FAM172A 0.93 7.91 0.58 1.22e-12 Diabetic retinopathy; TGCT cis rs7666738 0.791 rs1896156 chr4:99020882 C/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8180040 0.587 rs62246398 chr3:47066203 A/C cg27129171 chr3:47204927 SETD2 -0.71 -8.51 -0.61 4.8e-14 Colorectal cancer; TGCT cis rs10791323 0.572 rs10894755 chr11:133739685 C/T cg15485101 chr11:133734466 NA -0.41 -5.92 -0.47 2.96e-8 Childhood ear infection; TGCT cis rs9902453 0.817 rs55758314 chr17:28173978 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs12210905 1.000 rs12214930 chr6:27093715 C/T cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs9527 0.615 rs10883781 chr10:104581130 A/G cg15744005 chr10:104629667 AS3MT -0.5 -5.81 -0.46 4.91e-8 Arsenic metabolism; TGCT cis rs7917772 0.503 rs7914389 chr10:104295402 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6087771 0.926 rs6058431 chr20:30297133 C/T cg13852791 chr20:30311386 BCL2L1 0.82 7.74 0.57 3.03e-12 Subcortical brain region volumes;Putamen volume; TGCT trans rs7618501 0.602 rs2071207 chr3:50159844 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.5 -0.65 2.02e-16 Intelligence (multi-trait analysis); TGCT cis rs2469997 1.000 rs2447179 chr8:120355775 A/G cg00681363 chr8:120844660 TAF2 0.65 4.52 0.38 1.45e-5 Hypertension (SNP x SNP interaction); TGCT cis rs1799949 1.000 rs8176318 chr17:41197274 G/T cg10047753 chr17:41438598 NA 0.92 8.71 0.62 1.57e-14 Menopause (age at onset); TGCT cis rs7666738 0.830 rs921523 chr4:98841659 C/T cg18180107 chr4:99064573 C4orf37 0.5 4.47 0.37 1.72e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs56399783 0.803 rs17132665 chr7:2802173 T/C cg19731401 chr7:2775893 GNA12 0.35 5.07 0.41 1.38e-6 Childhood ear infection; TGCT cis rs28595532 0.920 rs115860303 chr4:119734526 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7302981 0.967 rs7972842 chr12:50516323 G/T cg23855989 chr12:50355821 AQP5 -0.3 -4.44 -0.37 2e-5 Systolic blood pressure; TGCT cis rs9368481 0.700 rs6911401 chr6:26913214 C/G cg07220782 chr6:26987966 LOC100270746;C6orf41 0.47 4.92 0.4 2.72e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs3858526 0.628 rs1840177 chr11:5944627 T/G cg24799795 chr11:5959658 NA 0.38 4.55 0.38 1.24e-5 DNA methylation (variation); TGCT cis rs7621025 0.586 rs34553037 chr3:136379413 T/C cg15507776 chr3:136538369 TMEM22 -0.51 -4.44 -0.37 2e-5 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs7044106 0.791 rs7036766 chr9:123479621 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.85 0.4 3.57e-6 Hip circumference adjusted for BMI; TGCT trans rs208520 0.690 rs1233103 chr6:66855943 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs1949733 1.000 rs3103071 chr4:8508579 C/G cg13073564 chr4:8508604 NA 0.46 4.83 0.4 3.89e-6 Response to antineoplastic agents; TGCT cis rs10488031 0.867 rs17170841 chr7:37073212 G/C cg06458904 chr7:36312573 EEPD1 0.51 4.5 0.37 1.54e-5 QT interval; TGCT cis rs597539 0.652 rs674654 chr11:68698762 G/T cg04772025 chr11:68637568 NA 0.6 6.75 0.52 5.08e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11948739 0.610 rs1363695 chr5:130378027 C/T cg08523029 chr5:130500466 HINT1 -0.6 -4.91 -0.4 2.82e-6 Pediatric bone mineral content (hip); TGCT trans rs2469997 0.858 rs1551785 chr8:120352397 T/A cg01792902 chr3:178864926 PIK3CA 0.8 6.91 0.53 2.21e-10 Hypertension (SNP x SNP interaction); TGCT cis rs8017423 0.967 rs12889636 chr14:90689953 A/C cg04374321 chr14:90722782 PSMC1 -0.76 -7.83 -0.58 1.9e-12 Mortality in heart failure; TGCT cis rs894734 0.535 rs10783613 chr12:54321966 G/T cg17708016 chr12:54321992 NA 0.69 5.69 0.46 8.48e-8 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); TGCT cis rs727505 1.000 rs67939974 chr7:124554364 C/T cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs2346177 0.846 rs62138876 chr2:46650672 C/A cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.79 -0.39 4.75e-6 HDL cholesterol; TGCT cis rs11098499 0.604 rs17051352 chr4:120581427 G/A cg09307838 chr4:120376055 NA 0.62 5.8 0.46 5.24e-8 Corneal astigmatism; TGCT cis rs10791097 0.967 rs10894268 chr11:130717153 C/T cg12179176 chr11:130786555 SNX19 0.65 6.88 0.53 2.63e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10479542 0.929 rs10074573 chr5:178976966 C/T cg19626725 chr5:178986131 RUFY1 -0.44 -5.61 -0.45 1.26e-7 Lung cancer; TGCT cis rs875971 0.928 rs2036263 chr7:65800197 C/T cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.43e-7 Aortic root size; TGCT cis rs17122693 0.748 rs72681636 chr14:51145871 G/T cg04730355 chr14:51134070 SAV1 1.33 12.04 0.73 1.37e-22 Cognitive performance; TGCT cis rs13064411 0.696 rs13325046 chr3:113104444 C/T cg18753928 chr3:113234510 CCDC52 -0.73 -5.54 -0.45 1.72e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs473651 0.935 rs477041 chr2:239355995 C/G cg08773314 chr2:239334832 ASB1 -0.48 -8.19 -0.59 2.68e-13 Multiple system atrophy; TGCT cis rs3020736 0.500 rs6002603 chr22:42492362 C/G cg15557168 chr22:42548783 NA 0.22 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7267979 1.000 rs2027004 chr20:25350618 C/T cg16686733 chr20:25566563 NINL -0.59 -6.07 -0.48 1.42e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3008870 1.000 rs12039172 chr1:67447450 A/G cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs950169 0.580 rs17532346 chr15:85171495 A/C cg11189052 chr15:85197271 WDR73 0.73 6.1 0.48 1.27e-8 Schizophrenia; TGCT cis rs526231 0.819 rs26234 chr5:102597156 G/A cg05225461 chr5:102596755 C5orf30 0.22 4.49 0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs61990749 0.597 rs3783980 chr14:78219807 T/C cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs8064299 0.636 rs9915279 chr17:72772848 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.91 10.11 0.67 6.76e-18 Monocyte count; TGCT cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg16145915 chr7:1198662 ZFAND2A -0.42 -4.89 -0.4 3.08e-6 Longevity;Endometriosis; TGCT cis rs916888 0.687 rs199456 chr17:44797919 C/T cg01570182 chr17:44337453 NA 1.09 10.0 0.67 1.26e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs929354 0.772 rs2023977 chr7:156996022 C/G cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs637571 0.522 rs542332 chr11:65744421 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.65 6.4 0.5 2.96e-9 Eosinophil percentage of white cells; TGCT cis rs11096990 0.634 rs6531706 chr4:39296167 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs9527 0.590 rs4917992 chr10:104786313 G/A cg15744005 chr10:104629667 AS3MT -0.42 -4.7 -0.39 6.75e-6 Arsenic metabolism; TGCT cis rs9560113 0.960 rs950891 chr13:112173992 G/A cg10483660 chr13:112241077 NA -0.33 -4.77 -0.39 5.11e-6 Menarche (age at onset); TGCT cis rs1059312 0.771 rs11059922 chr12:129290418 C/T cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs9486719 1.000 rs12207570 chr6:96987884 A/C cg18709589 chr6:96969512 KIAA0776 -0.71 -5.43 -0.44 2.89e-7 Migraine;Coronary artery disease; TGCT cis rs7666738 0.830 rs3907020 chr4:99038583 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2836950 0.520 rs2836966 chr21:40637521 A/G cg11644478 chr21:40555479 PSMG1 -0.56 -5.22 -0.42 7.38e-7 Menarche (age at onset); TGCT cis rs911555 0.713 rs2765051 chr14:103972379 T/C cg23461800 chr14:103021989 NA -0.35 -4.51 -0.38 1.5e-5 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg26531700 chr6:26746687 NA 0.61 5.84 0.46 4.23e-8 Intelligence (multi-trait analysis); TGCT cis rs7937682 0.632 rs4936834 chr11:111764017 T/A cg09085632 chr11:111637200 PPP2R1B 0.83 7.15 0.54 6.45e-11 Primary sclerosing cholangitis; TGCT trans rs797680 0.861 rs612037 chr1:93682878 G/A cg27528825 chr2:159282178 CCDC148 0.34 6.7 0.52 6.63e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1385374 0.858 rs959989 chr12:129292708 A/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs6978712 1.000 rs6962032 chr7:127151489 G/A cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs921968 0.509 rs556468 chr2:219355794 G/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs4478858 0.735 rs7523509 chr1:31788329 A/G cg00250761 chr1:31883323 NA -0.27 -4.76 -0.39 5.29e-6 Alcohol dependence; TGCT cis rs9457247 1.000 rs1794693 chr6:167405670 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs7586879 1.000 rs12713419 chr2:25121853 G/A cg01884057 chr2:25150051 NA 0.29 5.15 0.42 9.75e-7 Body mass index; TGCT cis rs9611565 1.000 rs5758314 chr22:41762523 T/G cg17554472 chr22:41940697 POLR3H -0.4 -4.47 -0.37 1.73e-5 Vitiligo; TGCT cis rs896854 0.818 rs13262110 chr8:95926890 C/T cg13393036 chr8:95962371 TP53INP1 -0.59 -7.96 -0.58 9.23e-13 Type 2 diabetes; TGCT cis rs8017423 0.967 rs7154683 chr14:90700692 A/G cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs79349575 0.783 rs59270107 chr17:47026185 A/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs6121246 0.529 rs112367115 chr20:30178627 G/A cg13852791 chr20:30311386 BCL2L1 0.71 4.54 0.38 1.31e-5 Mean corpuscular hemoglobin; TGCT cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg07424592 chr7:64974309 NA -1.33 -7.99 -0.58 7.81e-13 Diabetic kidney disease; TGCT cis rs2439831 0.867 rs2412778 chr15:43660982 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs7731657 0.537 rs10066004 chr5:130304689 G/A cg08523029 chr5:130500466 HINT1 -0.59 -4.8 -0.4 4.4e-6 Fasting plasma glucose; TGCT cis rs459571 0.629 rs441233 chr9:136876021 A/G cg14405625 chr9:136855902 VAV2 0.33 4.87 0.4 3.34e-6 Platelet distribution width; TGCT cis rs13188771 0.651 rs10515312 chr5:100906519 G/T cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs3849570 0.732 rs11715625 chr3:81875938 A/T cg07356753 chr3:81810745 GBE1 -0.6 -5.31 -0.43 4.92e-7 Waist circumference;Body mass index; TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg20007245 chr22:24372913 LOC391322 -0.72 -7.42 -0.55 1.64e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.830 rs7672127 chr4:98938477 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.58 0.56 7.02e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.688 rs1884364 chr6:146337817 C/G cg23711669 chr6:146136114 FBXO30 0.66 6.24 0.49 6.25e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2120019 0.567 rs28844983 chr15:75178088 T/A cg09165964 chr15:75287851 SCAMP5 -0.88 -7.07 -0.54 9.73e-11 Blood trace element (Zn levels); TGCT cis rs40363 0.645 rs250627 chr16:3527050 G/A cg00484396 chr16:3507460 NAT15 0.41 6.02 0.48 1.82e-8 Tuberculosis; TGCT cis rs34172651 0.517 rs1465423 chr16:24772680 C/G cg06028605 chr16:24865363 SLC5A11 -0.41 -4.58 -0.38 1.13e-5 Intelligence (multi-trait analysis); TGCT cis rs6089584 0.888 rs2181590 chr20:60622843 T/C cg13665807 chr20:60559372 TAF4 -0.46 -4.9 -0.4 2.87e-6 Body mass index; TGCT trans rs1005277 0.541 rs2472177 chr10:38384015 T/G cg17830980 chr10:43048298 ZNF37B -0.84 -10.72 -0.69 2.25e-19 Extrinsic epigenetic age acceleration; TGCT cis rs12188164 0.515 rs11744936 chr5:412112 C/T cg22025206 chr5:502436 SLC9A3 -0.28 -4.9 -0.4 2.96e-6 Cystic fibrosis severity; TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg21237687 chr17:6899380 ALOX12 0.52 5.78 0.46 5.57e-8 Tonsillectomy; TGCT cis rs2239547 0.657 rs6445538 chr3:52874288 T/C cg11645453 chr3:52864694 ITIH4 0.35 5.88 0.47 3.57e-8 Schizophrenia; TGCT cis rs1218582 0.688 rs58629129 chr1:154910930 T/C cg09359103 chr1:154839909 KCNN3 -0.64 -12.27 -0.74 3.87e-23 Prostate cancer; TGCT cis rs6087990 0.806 rs1474738 chr20:31380309 G/A cg13636640 chr20:31349939 DNMT3B 1.01 13.26 0.77 1.6e-25 Ulcerative colitis; TGCT trans rs117132860 0.661 rs4329181 chr7:17108209 G/T cg25519926 chr7:130132360 MEST;MESTIT1 0.95 6.9 0.53 2.32e-10 Cutaneous squamous cell carcinoma; TGCT cis rs7000551 0.725 rs2443496 chr8:22365788 G/A cg12081754 chr8:22256438 SLC39A14 0.28 4.48 0.37 1.68e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9611565 0.559 rs5751160 chr22:42175695 A/G cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs7666738 0.546 rs17546687 chr4:98769266 T/A cg05340658 chr4:99064831 C4orf37 0.52 5.7 0.46 8.44e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9399135 0.967 rs9389261 chr6:135371148 C/G cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs4319547 0.698 rs4039670 chr12:122822655 A/G cg08088222 chr12:122070432 ORAI1 0.26 4.66 0.39 8.01e-6 Body mass index; TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg25767906 chr1:53392781 SCP2 -0.6 -7.71 -0.57 3.49e-12 Monocyte count; TGCT cis rs7666738 0.546 rs3911415 chr4:98692401 T/A cg05340658 chr4:99064831 C4orf37 0.52 5.75 0.46 6.63e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 0.845 rs2259855 chr17:28097860 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -7.19 -0.54 5.27e-11 Coffee consumption (cups per day); TGCT cis rs1005277 0.505 rs200939 chr10:38139483 T/C cg13531842 chr10:38383804 ZNF37A -0.39 -4.59 -0.38 1.07e-5 Extrinsic epigenetic age acceleration; TGCT cis rs769267 0.965 rs1469712 chr19:19528821 C/A cg03709012 chr19:19516395 GATAD2A 0.76 6.42 0.5 2.64e-9 Tonsillectomy; TGCT cis rs3806843 0.576 rs246027 chr5:140333601 A/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs3820068 0.581 rs72645874 chr1:15926238 C/G cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs1488864 1.000 rs1973312 chr11:6352121 G/A cg12755421 chr11:6342214 PRKCDBP -0.6 -4.51 -0.38 1.47e-5 Smooth-surface caries; TGCT cis rs881375 0.678 rs2269060 chr9:123683569 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.42 4.96 0.41 2.3e-6 Rheumatoid arthritis; TGCT cis rs41271951 0.512 rs7537292 chr1:151071038 C/G cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs9611565 0.572 rs139569 chr22:42211141 A/G cg13695892 chr22:41940480 POLR3H -0.79 -7.5 -0.56 1.04e-11 Vitiligo; TGCT cis rs7829975 0.514 rs2979139 chr8:8268313 A/G cg06636001 chr8:8085503 FLJ10661 0.72 6.28 0.49 5.23e-9 Mood instability; TGCT cis rs13191362 0.810 rs13200053 chr6:163011443 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs561341 1.000 rs506766 chr17:30289659 T/C cg20587970 chr11:113659929 NA -1.03 -10.74 -0.69 1.99e-19 Hip circumference adjusted for BMI; TGCT cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg04013166 chr16:89971882 TCF25 0.32 4.72 0.39 6.22e-6 Skin colour saturation; TGCT cis rs1865760 0.516 rs9393684 chr6:26075531 G/C cg16482183 chr6:26056742 HIST1H1C 0.57 4.99 0.41 1.96e-6 Height; TGCT cis rs4665809 1.000 rs4665811 chr2:26260017 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.07 -0.48 1.45e-8 Gut microbiome composition (summer); TGCT cis rs68170813 0.559 rs6946036 chr7:106853659 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs2153535 0.542 rs9505465 chr6:8510846 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.49e-8 Motion sickness; TGCT cis rs4285028 0.948 rs12497349 chr3:121708517 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs6570726 0.846 rs409553 chr6:145886963 C/T cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3008870 0.959 rs2985826 chr1:67412918 G/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.91 0.73 2.83e-22 Lymphocyte percentage of white cells; TGCT cis rs151997 0.629 rs27288 chr5:50194920 T/A cg06027927 chr5:50259733 NA 0.56 5.78 0.46 5.72e-8 Callous-unemotional behaviour; TGCT cis rs12579753 1.000 rs12367791 chr12:82237278 C/T cg07988820 chr12:82153109 PPFIA2 -0.61 -6.52 -0.51 1.62e-9 Resting heart rate; TGCT cis rs6500602 0.787 rs7204624 chr16:4459834 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.34 0.49 3.97e-9 Schizophrenia; TGCT cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg04389838 chr3:44770851 ZNF501 -0.38 -4.83 -0.4 4.01e-6 Depressive symptoms; TGCT cis rs11673344 0.542 rs826325 chr19:37494482 A/G cg08039142 chr19:36980659 ZNF566 0.57 5.36 0.43 3.88e-7 Obesity-related traits; TGCT cis rs12220238 1.000 rs10824101 chr10:75947438 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7772486 0.719 rs702307 chr6:145993454 C/G cg05347473 chr6:146136440 FBXO30 -0.53 -4.97 -0.41 2.18e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs34754277 0.636 rs1627787 chr1:118165973 C/T cg11819305 chr1:117910798 MAN1A2 -0.5 -4.46 -0.37 1.8e-5 Immature fraction of reticulocytes; TGCT cis rs1577917 1.000 rs34106666 chr6:86676258 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.39e-7 Response to antipsychotic treatment; TGCT cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs35883536 0.551 rs6666607 chr1:101032368 A/G cg06223162 chr1:101003688 GPR88 -0.42 -7.96 -0.58 9.26e-13 Monocyte count; TGCT cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs8044995 0.563 rs55968019 chr16:68398111 G/A cg05110241 chr16:68378359 PRMT7 -0.36 -4.46 -0.37 1.84e-5 Schizophrenia; TGCT cis rs17345786 0.861 rs11711808 chr3:101235101 T/C cg12386194 chr3:101231763 SENP7 0.64 5.97 0.47 2.28e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7027203 0.576 rs4415381 chr9:96554603 A/G cg13679303 chr9:96623674 NA 0.53 7.61 0.56 6.13e-12 DNA methylation (variation); TGCT cis rs9788721 0.836 rs17483548 chr15:78730313 G/A cg18825076 chr15:78729989 IREB2 -0.35 -5.22 -0.42 7.15e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs754133 0.535 rs7315495 chr12:54440445 A/T cg16264616 chr12:54390824 NA 0.37 5.19 0.42 8.34e-7 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs1799949 0.860 rs8176279 chr17:41210396 A/C cg23758822 chr17:41437982 NA 0.73 7.14 0.54 6.88e-11 Menopause (age at onset); TGCT cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg04744514 chr10:134541379 INPP5A -0.25 -4.63 -0.38 9.09e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.51 0.65 1.99e-16 Platelet count; TGCT cis rs853679 0.527 rs9461443 chr6:28194629 A/T cg12963246 chr6:28129442 ZNF389 0.46 4.52 0.38 1.43e-5 Depression; TGCT cis rs9393777 0.513 rs7759969 chr6:26663096 T/A cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs5769707 0.967 rs9616713 chr22:50049109 G/A cg05373962 chr22:49881684 NA -0.31 -6.31 -0.49 4.55e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg06238570 chr21:40685208 BRWD1 0.7 6.46 0.5 2.16e-9 Cognitive function; TGCT cis rs7666738 0.830 rs28867087 chr4:98880349 T/A cg17366294 chr4:99064904 C4orf37 0.74 7.62 0.56 5.55e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs57506017 0.585 rs5011439 chr7:12268811 G/C cg07541786 chr7:12610355 SCIN 0.45 4.58 0.38 1.12e-5 Neuroticism; TGCT cis rs13082711 0.558 rs640912 chr3:27364092 C/A cg02860705 chr3:27208620 NA 0.29 4.66 0.39 8.01e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7617773 0.780 rs36075665 chr3:48343087 C/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs9914988 0.778 rs9907185 chr17:27122414 C/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1406084 0.636 rs12693840 chr2:154724799 A/G cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs12188164 1.000 rs56042615 chr5:437667 G/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.76 -0.39 5.33e-6 Cystic fibrosis severity; TGCT cis rs1865760 0.963 rs1540273 chr6:25924158 T/C cg16482183 chr6:26056742 HIST1H1C 0.51 4.59 0.38 1.06e-5 Height; TGCT cis rs2404602 0.692 rs56193230 chr15:76934472 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg08280861 chr8:58055591 NA -0.37 -4.8 -0.4 4.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs10875746 0.729 rs11168355 chr12:48410978 A/G cg20731937 chr12:48336164 NA -0.63 -5.34 -0.43 4.25e-7 Longevity (90 years and older); TGCT cis rs4253772 0.591 rs8143066 chr22:46656607 C/T cg09491104 chr22:46646882 C22orf40 -0.63 -6.39 -0.5 3.05e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs556990 0.760 rs3024739 chr13:113819948 G/A cg00898013 chr13:113819073 PROZ -0.51 -6.13 -0.48 1.06e-8 Blood protein levels; TGCT cis rs17059066 0.764 rs11962398 chr6:130622609 C/T cg25049486 chr6:130544510 SAMD3 0.38 4.52 0.38 1.41e-5 Mosquito bite size; TGCT cis rs11792861 0.591 rs2275641 chr9:111696389 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.67 7.67 0.57 4.34e-12 Menarche (age at onset); TGCT cis rs1887596 0.672 rs4771002 chr13:27201568 A/G cg01312412 chr13:27282625 NA 0.3 5.31 0.43 4.89e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs6684514 1.000 rs2277870 chr1:156246792 C/T cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs826838 0.967 rs1719856 chr12:39127201 C/T cg26384229 chr12:38710491 ALG10B -0.86 -7.72 -0.57 3.37e-12 Heart rate; TGCT cis rs56104184 0.775 rs56146968 chr19:49398847 A/G cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs909674 0.818 rs5757680 chr22:39844793 C/T cg01416388 chr22:39784598 NA 0.69 6.32 0.49 4.37e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg20276088 chr3:133502917 NA 0.28 6.07 0.48 1.42e-8 Iron status biomarkers; TGCT cis rs801193 1.000 rs2707850 chr7:66203870 G/T cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.97e-7 Aortic root size; TGCT cis rs3540 0.512 rs3862434 chr15:91080387 C/T cg22089800 chr15:90895588 ZNF774 0.76 7.91 0.58 1.21e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs10927875 0.541 rs1048237 chr1:16341733 T/C cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs1532993 0.518 rs1508469 chr4:98575375 T/C cg05340658 chr4:99064831 C4orf37 -0.42 -5.05 -0.41 1.57e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs7917772 0.582 rs10786684 chr10:104323028 A/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.59 -5.73 -0.46 7.1e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs55883249 1.000 rs55883249 chr2:9741535 C/A cg23886495 chr2:9695866 ADAM17 0.82 5.01 0.41 1.86e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs7635838 0.718 rs2594991 chr3:11362704 G/A cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs4794202 0.534 rs8078688 chr17:45919869 T/C cg02219949 chr17:45927392 SP6 0.37 4.47 0.37 1.76e-5 Alzheimer's disease (cognitive decline); TGCT cis rs10504229 0.679 rs1442125 chr8:58036258 A/C cg08280861 chr8:58055591 NA -0.34 -5.01 -0.41 1.81e-6 Developmental language disorder (linguistic errors); TGCT cis rs539096 0.602 rs1143702 chr1:44086831 C/T cg12908607 chr1:44402522 ARTN -0.43 -4.8 -0.4 4.43e-6 Intelligence (multi-trait analysis); TGCT trans rs4332037 0.539 rs11764590 chr7:2032803 C/T cg25206134 chr2:45395956 NA 0.97 7.33 0.55 2.6e-11 Bipolar disorder; TGCT cis rs892961 0.932 rs11657961 chr17:75405407 C/T cg05865280 chr17:75406074 SEPT9 0.29 6.76 0.52 4.91e-10 Airflow obstruction; TGCT trans rs62103177 0.513 rs9945153 chr18:77598450 C/T cg05926928 chr17:57297772 GDPD1 1.22 11.62 0.72 1.41e-21 Opioid sensitivity; TGCT cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs2836950 0.520 rs11911087 chr21:40665192 G/A cg11644478 chr21:40555479 PSMG1 -0.56 -5.22 -0.42 7.38e-7 Menarche (age at onset); TGCT trans rs916888 0.773 rs199445 chr17:44817408 C/T cg01341218 chr17:43662625 NA 1.11 9.15 0.63 1.43e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6723226 0.803 rs176415 chr2:32649778 G/A cg02381751 chr2:32503542 YIPF4 -0.57 -5.13 -0.42 1.09e-6 Intelligence (multi-trait analysis); TGCT cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg25811766 chr13:21894605 NA 0.26 5.27 0.43 5.79e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs4455778 0.659 rs12673347 chr7:49025613 C/G cg26309511 chr7:48887640 NA 0.44 5.31 0.43 4.87e-7 Lung cancer in never smokers; TGCT cis rs2439831 0.867 rs4075674 chr15:43650230 A/C cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs6674970 0.501 rs6691701 chr1:151001583 G/A cg00666978 chr1:150947442 LASS2 -0.56 -4.46 -0.37 1.78e-5 Childhood ear infection; TGCT cis rs7100689 0.646 rs10466235 chr10:82149655 C/T cg01528321 chr10:82214614 TSPAN14 -0.69 -7.02 -0.53 1.27e-10 Post bronchodilator FEV1; TGCT cis rs36051895 0.623 rs7847811 chr9:5237081 T/C cg02405213 chr9:5042618 JAK2 -0.68 -8.01 -0.58 7.18e-13 Pediatric autoimmune diseases; TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg01802117 chr1:53393560 SCP2 -0.44 -5.23 -0.43 6.9e-7 Monocyte count; TGCT cis rs7666738 0.753 rs13122897 chr4:98936185 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs13138063 chr4:99050438 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.898 rs4698620 chr4:17587361 C/T cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs2727020 0.729 rs4315497 chr11:49214499 G/A cg15704280 chr7:45808275 SEPT13 0.7 7.71 0.57 3.59e-12 Coronary artery disease; TGCT cis rs11078884 0.527 rs2760748 chr17:2001604 T/A cg21733020 chr17:2599052 KIAA0664 0.33 4.76 0.39 5.4e-6 Metabolite levels (5-HIAA); TGCT trans rs6089829 0.962 rs4809455 chr20:61660781 G/C cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1218582 0.772 rs2335408 chr1:154915977 G/A cg24250549 chr1:154909240 PMVK 0.62 6.21 0.49 7.36e-9 Prostate cancer; TGCT cis rs4699052 0.507 rs7662107 chr4:104258396 C/T cg16532752 chr4:104119610 CENPE -0.7 -6.07 -0.48 1.45e-8 Testicular germ cell tumor; TGCT cis rs9916302 0.706 rs4488484 chr17:37717377 A/T cg03321784 chr17:37729644 NA -0.44 -4.49 -0.37 1.6e-5 Glomerular filtration rate (creatinine); TGCT cis rs7178572 0.568 rs11632941 chr15:77533888 A/G cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg25767906 chr1:53392781 SCP2 -0.51 -6.21 -0.49 7.42e-9 Monocyte count; TGCT cis rs6693567 0.565 rs12739706 chr1:150261653 C/G cg09579323 chr1:150459698 TARS2 -0.53 -4.81 -0.4 4.38e-6 Migraine; TGCT cis rs9611565 0.592 rs5758405 chr22:42076381 C/A cg06634786 chr22:41940651 POLR3H 0.9 9.03 0.63 2.7e-15 Vitiligo; TGCT cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg10047753 chr17:41438598 NA 0.92 8.63 0.61 2.49e-14 Menopause (age at onset); TGCT cis rs611744 0.503 rs13282220 chr8:109263043 T/C cg21045802 chr8:109455806 TTC35 0.7 6.88 0.53 2.63e-10 Dupuytren's disease; TGCT cis rs9325144 0.647 rs4616077 chr12:39092364 T/C cg10518543 chr12:38710700 ALG10B -0.49 -4.58 -0.38 1.11e-5 Morning vs. evening chronotype; TGCT cis rs17162190 0.590 rs4659374 chr1:26779270 C/T cg02450742 chr1:26856648 RPS6KA1 -0.56 -4.68 -0.39 7.47e-6 Mean corpuscular volume; TGCT cis rs9926296 0.682 rs645019 chr16:89716883 C/T cg03388025 chr16:89894329 SPIRE2 -0.35 -5.19 -0.42 8.38e-7 Vitiligo; TGCT cis rs7666738 0.830 rs7691864 chr4:98971376 G/C cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7607369 0.791 rs72965151 chr2:219344165 G/T cg02176678 chr2:219576539 TTLL4 -0.48 -6.79 -0.52 4.17e-10 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs473651 0.503 rs515342 chr2:239367296 A/G cg18131467 chr2:239335373 ASB1 -0.86 -7.24 -0.55 4.1e-11 Multiple system atrophy; TGCT cis rs514406 0.505 rs431427 chr1:53179094 C/A cg16325326 chr1:53192061 ZYG11B 0.85 12.13 0.74 8.13e-23 Monocyte count; TGCT cis rs11085466 1.000 rs73552479 chr19:21778816 G/T cg02997983 chr19:21646781 NA -0.6 -4.6 -0.38 1.03e-5 Colorectal or endometrial cancer; TGCT cis rs7940866 0.845 rs1991899 chr11:130801649 C/T cg12179176 chr11:130786555 SNX19 -0.56 -5.64 -0.45 1.1e-7 Schizophrenia; TGCT cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg04025307 chr7:1156635 C7orf50 0.23 5.55 0.45 1.64e-7 Longevity;Endometriosis; TGCT cis rs10484885 0.775 rs17584945 chr6:90512776 T/C cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.51 -0.38 1.46e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2898290 0.617 rs13273172 chr8:11461111 A/G cg21775007 chr8:11205619 TDH -0.47 -4.52 -0.38 1.41e-5 Systolic blood pressure; TGCT cis rs7590720 1.000 rs4674051 chr2:216907512 G/C cg12620499 chr2:216877984 MREG 0.88 8.99 0.63 3.55e-15 Alcohol dependence; TGCT cis rs4727027 0.866 rs7778766 chr7:148806729 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.6 0.38 1.04e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2274273 0.622 rs11846809 chr14:55401782 T/C cg01923255 chr14:55878535 KIAA0831 0.53 4.53 0.38 1.36e-5 Protein biomarker; TGCT cis rs826838 0.802 rs10785619 chr12:38742897 T/A cg13010199 chr12:38710504 ALG10B 0.68 5.53 0.44 1.79e-7 Heart rate; TGCT cis rs7043114 0.563 rs7848391 chr9:95337520 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.23 -0.42 7.08e-7 Height; TGCT cis rs7208859 0.673 rs57432042 chr17:29241038 T/C cg18442181 chr17:29233375 C17orf42 -0.77 -4.49 -0.37 1.6e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7542091 0.669 rs11119357 chr1:210042382 C/T cg22029157 chr1:209979665 IRF6 0.65 6.27 0.49 5.56e-9 Monobrow; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg25703541 chr22:24373054 LOC391322 0.85 7.26 0.55 3.8e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7698623 0.850 rs1381958 chr4:88796785 T/C cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT cis rs2797160 0.905 rs1418641 chr6:125999854 C/T cg05901451 chr6:126070800 HEY2 -0.74 -6.48 -0.5 1.96e-9 Endometrial cancer; TGCT cis rs877282 0.891 rs11253355 chr10:768367 C/G cg17470449 chr10:769945 NA 0.34 5.15 0.42 9.77e-7 Uric acid levels; TGCT cis rs2797160 0.967 rs1739355 chr6:126018114 A/G cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs2456568 0.867 rs1827931 chr11:93663170 T/C cg17595323 chr11:93583763 C11orf90 -0.46 -5.85 -0.47 4e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7666738 0.716 rs2865982 chr4:99031661 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.583 rs2776306 chr21:40713754 A/G cg17971929 chr21:40555470 PSMG1 0.61 5.62 0.45 1.22e-7 Cognitive function; TGCT cis rs910316 0.737 rs175499 chr14:75535927 G/A cg11812906 chr14:75593930 NEK9 -0.62 -5.7 -0.46 8.15e-8 Height; TGCT cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg03452623 chr4:187889614 NA -0.38 -5.66 -0.45 9.76e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs1371867 1.000 rs1371867 chr8:101330209 A/C cg06002616 chr8:101225028 SPAG1 -0.48 -5.6 -0.45 1.29e-7 Atrioventricular conduction; TGCT cis rs7010267 0.596 rs6996754 chr8:120034870 T/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs617219 0.698 rs12189248 chr5:78517143 A/G cg09550809 chr5:78407562 BHMT -0.43 -5.95 -0.47 2.51e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7412746 0.622 rs72704654 chr1:150826410 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 4.75 0.39 5.55e-6 Melanoma; TGCT cis rs2066819 1.000 rs77131854 chr12:56664231 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs9814567 0.963 rs9844537 chr3:134238341 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -9.2 -0.64 1.11e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg07507251 chr3:52567010 NT5DC2 0.45 5.99 0.47 2.1e-8 Bipolar disorder; TGCT cis rs9733 0.596 rs12085275 chr1:150650265 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs10206020 0.885 rs11887527 chr2:1578080 A/G cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg11502198 chr6:26597334 ABT1 0.53 4.93 0.41 2.53e-6 Intelligence (multi-trait analysis); TGCT cis rs2486012 0.826 rs2993621 chr1:44372291 T/C cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs2299587 0.543 rs12546204 chr8:17796871 A/C cg01800426 chr8:17659068 MTUS1 -0.63 -5.39 -0.44 3.41e-7 Economic and political preferences; TGCT cis rs12142240 0.698 rs41293273 chr1:46806393 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.78 -0.39 4.78e-6 Menopause (age at onset); TGCT cis rs13108904 0.518 rs4974603 chr4:1343168 C/T cg00684032 chr4:1343700 KIAA1530 0.24 4.93 0.41 2.53e-6 Obesity-related traits; TGCT cis rs597539 0.652 rs667989 chr11:68685776 T/A cg21862992 chr11:68658383 NA 0.44 6.01 0.47 1.93e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6540559 0.673 rs4556361 chr1:210019654 C/G cg21951975 chr1:209979733 IRF6 -0.6 -4.61 -0.38 9.67e-6 Cleft lip with or without cleft palate; TGCT cis rs1372520 0.684 rs2619347 chr4:90745770 G/A cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs2841277 0.708 rs11623422 chr14:105407031 A/G cg19901468 chr14:105411992 AHNAK2 -0.28 -6.09 -0.48 1.31e-8 Rheumatoid arthritis; TGCT cis rs2847281 0.614 rs888269 chr18:12774860 G/C cg23598886 chr18:12777645 NA 0.37 4.69 0.39 7.07e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs7208859 0.623 rs122898 chr17:28905254 C/T cg13385521 chr17:29058706 SUZ12P -0.8 -4.89 -0.4 3.12e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1218582 0.772 rs10796935 chr1:154891363 G/T cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs4700695 0.614 rs930066 chr5:65207836 G/A cg21114390 chr5:65439923 SFRS12 0.67 4.69 0.39 7.07e-6 Facial morphology (factor 19); TGCT cis rs4776059 1.000 rs12914047 chr15:52970993 G/A cg25063058 chr15:52860530 ARPP19 0.53 4.76 0.39 5.35e-6 Schizophrenia; TGCT cis rs3960554 0.808 rs867973 chr7:75686007 G/A cg17325771 chr7:75508891 RHBDD2 -0.54 -4.63 -0.38 8.97e-6 Eotaxin levels; TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg11494091 chr17:61959527 GH2 0.61 14.78 0.8 4.02e-29 Prudent dietary pattern; TGCT cis rs7674212 0.581 rs13150953 chr4:103942498 A/G cg16532752 chr4:104119610 CENPE -0.56 -4.92 -0.4 2.64e-6 Type 2 diabetes; TGCT cis rs916888 0.773 rs199448 chr17:44809001 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 -0.6 -5.26 -0.43 6.18e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg11003573 chr3:44754125 ZNF502 -0.41 -4.67 -0.39 7.57e-6 Depressive symptoms; TGCT cis rs7267979 0.816 rs3746337 chr20:25208272 C/T cg16686733 chr20:25566563 NINL 0.51 4.81 0.4 4.25e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg24829409 chr8:58192753 C8orf71 -0.55 -5.2 -0.42 7.84e-7 Developmental language disorder (linguistic errors); TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.51 5.69 0.46 8.51e-8 Lymphocyte counts; TGCT cis rs72781680 1.000 rs17711825 chr2:24124578 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs13392177 0.647 rs6718220 chr2:219066518 T/C cg00012203 chr2:219082015 ARPC2 -0.75 -7.53 -0.56 8.88e-12 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs6964587 0.626 rs7785941 chr7:91531024 T/C cg17063962 chr7:91808500 NA -0.73 -6.94 -0.53 1.98e-10 Breast cancer; TGCT cis rs7772486 0.754 rs9399561 chr6:145955687 C/G cg13319975 chr6:146136371 FBXO30 -0.56 -5.06 -0.41 1.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1891275 0.515 rs7092884 chr10:93483872 A/C cg07889827 chr10:93443413 NA 0.31 6.27 0.49 5.47e-9 Intelligence (multi-trait analysis); TGCT cis rs950776 0.684 rs61012457 chr15:78865694 C/G cg06917634 chr15:78832804 PSMA4 0.69 5.43 0.44 2.84e-7 Sudden cardiac arrest; TGCT cis rs1580019 0.523 rs9791770 chr7:32582252 C/A cg07520158 chr7:32535189 LSM5;AVL9 0.6 4.95 0.41 2.39e-6 Cognitive ability; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 15.48 0.81 9.24e-31 Prudent dietary pattern; TGCT cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs9372253 0.678 rs9372251 chr6:110700656 A/G cg19196401 chr6:110721138 DDO -0.43 -5.95 -0.47 2.53e-8 Platelet distribution width; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg14159672 chr1:205819179 PM20D1 0.75 10.73 0.69 2.11e-19 Menarche (age at onset); TGCT cis rs6988636 1.000 rs62521841 chr8:124194625 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg13395646 chr4:1353034 KIAA1530 -0.47 -6.15 -0.48 9.8e-9 Obesity-related traits; TGCT cis rs78456975 0.527 rs72776299 chr2:1570300 G/C cg01028140 chr2:1542097 TPO -0.33 -5.09 -0.42 1.26e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT trans rs1814175 0.529 rs1988417 chr11:49932430 A/G cg11707556 chr5:10655725 ANKRD33B -0.41 -8.7 -0.62 1.69e-14 Height; TGCT cis rs6060960 0.502 rs15817 chr20:30193538 A/G cg18721089 chr20:30220636 NA -0.57 -6.22 -0.49 6.83e-9 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs801193 0.527 rs2707837 chr7:66181073 G/C cg11764359 chr7:65958608 NA 0.54 4.85 0.4 3.67e-6 Aortic root size; TGCT cis rs9926296 0.569 rs4785708 chr16:89796569 C/T cg08627397 chr16:89984028 MC1R 0.3 4.85 0.4 3.69e-6 Vitiligo; TGCT trans rs6089829 0.888 rs4809467 chr20:61671688 A/G cg23505145 chr19:12996616 KLF1 0.96 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT trans rs1974653 0.672 rs113307754 chr22:20089271 A/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs7552404 1.000 rs4949872 chr1:76131392 C/G cg22875332 chr1:76189707 ACADM 0.8 9.91 0.66 2.06e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs344364 0.511 rs12599337 chr16:1946751 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 0.42 4.66 0.39 8.15e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs79349575 0.811 rs80032154 chr17:47014992 C/A cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.06e-8 Type 2 diabetes; TGCT cis rs6582630 0.638 rs11182428 chr12:38526387 T/C cg26384229 chr12:38710491 ALG10B -0.55 -4.89 -0.4 3.05e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs3947 0.950 rs1692811 chr8:11703048 C/G cg02840367 chr8:11660030 FDFT1 0.91 6.66 0.51 7.98e-10 Blood protein levels; TGCT cis rs425277 0.958 rs626479 chr1:2110260 A/G cg24578937 chr1:2090814 PRKCZ -0.28 -6.99 -0.53 1.52e-10 Height; TGCT cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg19774624 chr17:42201019 HDAC5 -0.87 -10.75 -0.69 1.84e-19 Total body bone mineral density; TGCT trans rs3107575 0.572 rs73169366 chr3:165320307 C/T cg04140596 chr1:228404239 OBSCN 0.72 6.63 0.51 9.27e-10 Morning vs. evening chronotype; TGCT cis rs3733585 0.699 rs7658170 chr4:9966593 C/T cg00071950 chr4:10020882 SLC2A9 0.54 6.46 0.5 2.2e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9398235 0.929 rs2073211 chr6:110729270 A/G cg00083206 chr6:110721305 DDO 0.44 4.46 0.37 1.79e-5 Systemic lupus erythematosus; TGCT cis rs612683 0.694 rs6688364 chr1:101000874 G/A cg06223162 chr1:101003688 GPR88 0.34 5.72 0.46 7.52e-8 Breast cancer; TGCT cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs2688608 0.592 rs10762563 chr10:75524802 C/A cg19442545 chr10:75533431 FUT11 -0.36 -5.73 -0.46 7.17e-8 Inflammatory bowel disease; TGCT cis rs3733585 0.534 rs7375642 chr4:9955236 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs854765 0.520 rs7219324 chr17:17909775 C/T cg04398451 chr17:18023971 MYO15A 0.31 4.8 0.4 4.4e-6 Total body bone mineral density; TGCT cis rs7914558 0.966 rs11191518 chr10:104782853 C/G cg04362960 chr10:104952993 NT5C2 0.61 5.46 0.44 2.44e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs11122272 0.735 rs11122279 chr1:231519804 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs425277 1.000 rs12401379 chr1:2058580 G/C cg24578937 chr1:2090814 PRKCZ 0.32 7.65 0.57 4.86e-12 Height; TGCT cis rs6582630 0.555 rs10748382 chr12:38504529 C/T cg26384229 chr12:38710491 ALG10B 0.87 8.29 0.6 1.5700000000000001e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs13326165 0.760 rs55965068 chr3:52354432 A/G cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs735396 0.770 rs2257764 chr12:121446446 T/A cg15155738 chr12:121454335 C12orf43 -0.55 -4.76 -0.39 5.4e-6 N-glycan levels; TGCT cis rs2230307 0.536 rs56215716 chr1:100447486 G/A cg24955406 chr1:100503596 HIAT1 0.72 4.68 0.39 7.51e-6 Carotid intima media thickness; TGCT cis rs4319547 0.695 rs10846699 chr12:122853073 A/G cg05707623 chr12:122985044 ZCCHC8 0.63 5.02 0.41 1.74e-6 Body mass index; TGCT cis rs3862435 0.666 rs2601202 chr15:90958089 G/A cg14166756 chr15:90894880 ZNF774 -0.29 -4.76 -0.39 5.2e-6 Response to exercise (triglyceride level interaction); TGCT cis rs2303745 0.589 rs11882562 chr19:17395055 C/G cg02221750 chr19:17393354 ANKLE1 0.51 6.93 0.53 2.08e-10 Systemic lupus erythematosus; TGCT cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg07061783 chr6:25882402 NA 0.58 5.57 0.45 1.48e-7 Intelligence (multi-trait analysis); TGCT cis rs7017914 0.905 rs2732110 chr8:71926811 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs7104764 1.000 rs6598062 chr11:243712 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs6500602 0.647 rs1641868 chr16:4594503 G/C cg08645402 chr16:4508243 NA 0.18 5.04 0.41 1.58e-6 Schizophrenia; TGCT cis rs79349575 0.783 rs28409394 chr17:46998118 T/C cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs2797160 1.000 rs1739363 chr6:126020980 G/A cg05901451 chr6:126070800 HEY2 0.75 6.66 0.51 8e-10 Endometrial cancer; TGCT cis rs7666738 0.830 rs28497822 chr4:98906873 C/T cg05340658 chr4:99064831 C4orf37 0.53 6.32 0.49 4.21e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg24675658 chr1:53192096 ZYG11B -0.69 -8.0 -0.58 7.54e-13 Monocyte count; TGCT cis rs9906944 0.707 rs11655950 chr17:47129121 C/T cg07075026 chr17:47091521 IGF2BP1 -0.47 -5.06 -0.41 1.46e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs12291225 0.546 rs12291662 chr11:14342949 T/C cg19336497 chr11:14380999 RRAS2 -0.45 -7.25 -0.55 3.87e-11 Sense of smell; TGCT cis rs763121 0.853 rs138716 chr22:39146527 C/T cg06022373 chr22:39101656 GTPBP1 0.8 7.56 0.56 7.77e-12 Menopause (age at onset); TGCT cis rs13190036 1.000 rs71601344 chr5:176633493 G/A cg18465082 chr5:176734745 MXD3 0.32 4.46 0.37 1.78e-5 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs3087591 0.708 rs2854305 chr17:29647003 G/A cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT cis rs10423674 0.526 rs12462498 chr19:18832950 A/G cg20185461 chr19:18899082 COMP 0.5 4.86 0.4 3.49e-6 Menarche (age at onset); TGCT cis rs116095464 0.558 rs7708515 chr5:234989 C/G cg22857025 chr5:266934 NA -0.33 -6.73 -0.52 5.7e-10 Breast cancer; TGCT cis rs727563 0.635 rs5751141 chr22:42107745 A/G cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.35e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11651000 0.761 rs11079788 chr17:45820723 C/T cg06532163 chr17:45867833 NA 0.33 4.82 0.4 4.05e-6 IgG glycosylation; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg04234412 chr22:24373322 LOC391322 -0.91 -10.78 -0.7 1.62e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7267979 1.000 rs2387881 chr20:25378172 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg11965913 chr1:205819406 PM20D1 0.53 7.51 0.56 1.01e-11 Menarche (age at onset); TGCT cis rs9915657 0.773 rs9912974 chr17:70095963 C/T cg06234051 chr17:70120541 SOX9 -0.27 -5.68 -0.45 9.25e-8 Thyroid hormone levels; TGCT cis rs28595532 1.000 rs11931194 chr4:119631160 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.52 0.38 1.42e-5 Cannabis dependence symptom count; TGCT cis rs10858047 0.783 rs6692475 chr1:115209142 C/T cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs7937682 0.921 rs4534611 chr11:111440425 C/G cg09085632 chr11:111637200 PPP2R1B -0.86 -7.29 -0.55 3.21e-11 Primary sclerosing cholangitis; TGCT trans rs57221529 0.766 rs56216231 chr5:581193 G/A cg11887960 chr12:57824829 NA 1.06 9.28 0.64 6.78e-16 Lung disease severity in cystic fibrosis; TGCT cis rs597539 0.731 rs664229 chr11:68624483 C/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 7.55 0.56 8.19e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12142240 0.698 rs1475388 chr1:46816465 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs2268241 0.938 rs11088251 chr21:34770810 A/C cg14850771 chr21:34775459 IFNGR2 0.64 5.13 0.42 1.08e-6 Obesity-related traits; TGCT cis rs12497850 0.931 rs10780033 chr3:48891275 T/C cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs13177918 0.798 rs13182116 chr5:149845526 A/T cg14059543 chr5:149831962 NA 0.53 5.56 0.45 1.58e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7914558 0.966 rs7085598 chr10:104650128 T/C cg04362960 chr10:104952993 NT5C2 0.58 5.16 0.42 9.65e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs68170813 0.599 rs12532514 chr7:107000952 C/T cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT trans rs853410 0.516 rs6421941 chr6:3998448 C/T cg13911294 chr9:88951310 ZCCHC6 -0.64 -6.66 -0.51 8.02e-10 Night sleep phenotypes; TGCT trans rs10506458 0.834 rs12426893 chr12:63388120 G/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.5 -0.61 5.08e-14 Hemostatic factors and hematological phenotypes; TGCT trans rs7618501 0.601 rs2624825 chr3:50154989 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs9733 0.596 rs17658705 chr1:150678071 A/C cg09365446 chr1:150670422 GOLPH3L -0.31 -4.64 -0.38 8.7e-6 Tonsillectomy; TGCT cis rs7818688 0.654 rs75680386 chr8:95986148 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs12530845 1.000 rs4291212 chr7:135335465 C/T cg23117316 chr7:135346802 PL-5283 -0.51 -4.82 -0.4 4.1e-6 Red blood cell traits; TGCT cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs904251 0.600 rs1874736 chr6:37447994 C/G cg08126542 chr6:37504118 NA -0.4 -5.72 -0.46 7.64e-8 Cognitive performance; TGCT cis rs13272623 0.502 rs268628 chr8:71560505 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.61 -5.12 -0.42 1.12e-6 IgG glycosylation; TGCT cis rs1466788 0.965 rs6674413 chr1:110625110 C/T cg11787288 chr1:111506544 C1orf103 0.5 4.5 0.37 1.52e-5 Blood metabolite levels; TGCT cis rs6582630 0.638 rs35864536 chr12:38472255 T/A cg26384229 chr12:38710491 ALG10B -0.54 -4.83 -0.4 4.03e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs12210905 0.688 rs12191373 chr6:27484330 C/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs11123170 0.503 rs28679654 chr2:113967617 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.52 4.44 0.37 1.96e-5 Renal function-related traits (BUN); TGCT cis rs9303401 0.573 rs34717648 chr17:56886624 T/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs28595532 0.920 rs114963870 chr4:119758099 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs616402 0.527 rs604369 chr1:10567208 C/A cg17425144 chr1:10567563 PEX14 0.57 8.21 0.59 2.43e-13 Breast size; TGCT cis rs4665809 1.000 rs10048648 chr2:26320315 T/C cg04944784 chr2:26401820 FAM59B -0.68 -6.04 -0.48 1.7e-8 Gut microbiome composition (summer); TGCT cis rs6163 0.588 rs67506723 chr10:104509064 G/T cg05855489 chr10:104503620 C10orf26 0.98 12.37 0.74 2.13e-23 Waist circumference;Hip circumference; TGCT cis rs35883536 0.647 rs17402665 chr1:101046940 C/T cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs6687430 0.562 rs12139169 chr1:10635328 C/T cg17425144 chr1:10567563 PEX14 0.48 5.18 0.42 8.88e-7 Hand grip strength; TGCT cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg21963583 chr11:68658836 MRPL21 0.36 5.96 0.47 2.44e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2836974 0.899 rs34433511 chr21:40618883 A/C cg06238570 chr21:40685208 BRWD1 0.69 6.47 0.5 2.08e-9 Cognitive function; TGCT cis rs2742234 0.955 rs2503865 chr10:43659536 C/T cg02780029 chr10:43622663 RET -0.26 -4.98 -0.41 2.07e-6 Hirschsprung disease; TGCT cis rs7424096 0.613 rs17332671 chr2:37244124 C/G cg14987922 chr2:37194071 STRN 0.52 4.65 0.39 8.4e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs7726839 0.574 rs72707007 chr5:661856 T/C cg09021430 chr5:549028 NA -0.4 -5.63 -0.45 1.16e-7 Obesity-related traits; TGCT cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg13395646 chr4:1353034 KIAA1530 -0.39 -4.98 -0.41 2.13e-6 Obesity-related traits; TGCT cis rs473651 0.935 rs35080527 chr2:239351387 T/C cg18131467 chr2:239335373 ASB1 1.02 15.09 0.8 7.51e-30 Multiple system atrophy; TGCT cis rs1218582 0.772 rs4845682 chr1:154877105 T/C cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs9640161 0.789 rs4554381 chr7:150025567 G/A cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 9.08e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs67073037 0.955 rs12053141 chr2:29134743 A/G cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs9818758 0.607 rs13087930 chr3:48961726 A/G cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs11122272 0.735 rs10489610 chr1:231517765 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs4820539 0.966 rs5759600 chr22:23483769 C/A cg21100191 chr22:23484243 RTDR1 0.93 11.16 0.71 1.91e-20 Bone mineral density; TGCT cis rs3733585 0.699 rs6823361 chr4:9963127 A/G cg00071950 chr4:10020882 SLC2A9 -0.55 -6.55 -0.51 1.41e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs832540 0.669 rs832538 chr5:56200016 C/T cg24531977 chr5:56204891 C5orf35 -0.65 -6.39 -0.5 3.1e-9 Coronary artery disease; TGCT cis rs933688 0.818 rs10052492 chr5:90759930 T/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.16 0.59 3.2e-13 Smoking behavior; TGCT cis rs2066819 1.000 rs111885088 chr12:56657216 A/C cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs9457247 0.967 rs2149084 chr6:167370988 G/C cg23791538 chr6:167370224 RNASET2 0.51 4.98 0.41 2.09e-6 Crohn's disease; TGCT cis rs4664308 1.000 rs6759924 chr2:160912747 G/A cg03641300 chr2:160917029 PLA2R1 -0.26 -6.35 -0.5 3.77e-9 Idiopathic membranous nephropathy; TGCT cis rs2072499 0.833 rs2251636 chr1:156202809 G/C cg24450063 chr1:156163899 SLC25A44 1.01 12.65 0.75 4.62e-24 Testicular germ cell tumor; TGCT cis rs6665290 0.901 rs2104860 chr1:227208637 G/C cg10327440 chr1:227177885 CDC42BPA -0.9 -16.17 -0.82 2.56e-32 Myeloid white cell count; TGCT cis rs2239547 0.657 rs6445539 chr3:52874296 G/A cg10802521 chr3:52805072 NEK4 -0.65 -6.12 -0.48 1.16e-8 Schizophrenia; TGCT cis rs910316 1.000 rs7147118 chr14:75610170 G/C cg23033748 chr14:75592666 NEK9 0.28 4.79 0.39 4.73e-6 Height; TGCT cis rs9330316 0.611 rs56402128 chr2:110321071 C/T cg25199208 chr2:109402912 CCDC138 -0.42 -4.56 -0.38 1.19e-5 Schizophrenia; TGCT cis rs9486715 0.838 rs9386576 chr6:96954717 C/T cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs208515 0.525 rs12193560 chr6:66690457 A/T cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs6542838 0.641 rs6741166 chr2:99534926 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.55 -4.96 -0.41 2.29e-6 Fear of minor pain; TGCT cis rs926938 0.527 rs2335954 chr1:115534151 C/T cg12756093 chr1:115239321 AMPD1 -0.32 -4.67 -0.39 7.82e-6 Autism; TGCT cis rs763014 0.931 rs2071981 chr16:630025 C/G cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg11965913 chr1:205819406 PM20D1 0.61 9.63 0.65 1.01e-16 Menarche (age at onset); TGCT trans rs7618501 0.521 rs2883059 chr3:49902160 C/T cg21659725 chr3:3221576 CRBN -0.74 -8.33 -0.6 1.3e-13 Intelligence (multi-trait analysis); TGCT cis rs7619708 1 rs7619708 chr3:195810187 T/C cg16824377 chr3:195164118 ACAP2 -0.6 -4.56 -0.38 1.22e-5 Red cell distribution width; TGCT cis rs8051431 0.876 rs12443563 chr16:72018099 C/T cg06353428 chr16:71660113 MARVELD3 0.57 4.54 0.38 1.31e-5 LDL cholesterol levels; TGCT cis rs11585357 0.895 rs72633828 chr1:17632251 G/A cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs61990749 0.597 rs7147516 chr14:78153980 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.69 -0.39 7.04e-6 Fibroblast growth factor basic levels; TGCT cis rs2153535 0.580 rs915350 chr6:8443486 A/G cg07606381 chr6:8435919 SLC35B3 0.58 5.38 0.44 3.54e-7 Motion sickness; TGCT cis rs2760061 0.626 rs634106 chr1:228121548 C/T cg02753203 chr1:228287806 NA -0.34 -6.68 -0.51 7.2e-10 Diastolic blood pressure; TGCT cis rs12681287 0.640 rs4490816 chr8:87384938 T/C cg27223183 chr8:87520930 FAM82B 0.89 6.61 0.51 1.04e-9 Caudate activity during reward; TGCT trans rs459571 0.916 rs109536 chr9:136889987 G/C cg09836344 chr4:1243392 C4orf42;CTBP1 -0.75 -8.21 -0.59 2.47e-13 Platelet distribution width; TGCT cis rs56104184 0.779 rs17272666 chr19:49356294 T/C cg15549821 chr19:49342101 PLEKHA4 -0.76 -8.95 -0.63 4.37e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs8072100 0.666 rs6503804 chr17:45772447 G/A cg08085267 chr17:45401833 C17orf57 -0.43 -4.82 -0.4 4.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg03188948 chr7:1209495 NA 0.48 6.81 0.52 3.76e-10 Longevity;Endometriosis; TGCT cis rs514406 0.825 rs3863643 chr1:53224577 C/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.29e-11 Monocyte count; TGCT cis rs1887596 0.672 rs9553875 chr13:27210925 G/A cg01312412 chr13:27282625 NA 0.29 5.13 0.42 1.1e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs2180341 1.000 rs4897207 chr6:127605898 C/T cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs11971779 0.666 rs7786851 chr7:139007020 C/G cg07862535 chr7:139043722 LUC7L2 -0.65 -5.22 -0.42 7.26e-7 Diisocyanate-induced asthma; TGCT cis rs1372520 1.000 rs1372520 chr4:90757505 T/C cg14346243 chr4:90757452 SNCA -0.65 -5.32 -0.43 4.78e-7 Neuroticism; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg22105103 chr4:187893119 NA 0.33 4.53 0.38 1.35e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9640161 0.711 rs3800781 chr7:150027324 T/A cg17279839 chr7:150038598 RARRES2 0.43 4.54 0.38 1.29e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs10791323 0.660 rs2156681 chr11:133731644 G/T cg03690763 chr11:133734501 NA -0.28 -4.46 -0.37 1.83e-5 Childhood ear infection; TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg01516881 chr6:292596 DUSP22 -0.78 -8.17 -0.59 2.99e-13 Menopause (age at onset); TGCT cis rs4803468 1.000 rs2241711 chr19:41911980 T/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.69 -0.69 2.72e-19 Height; TGCT cis rs7949030 0.653 rs2516634 chr11:62367186 G/A cg11742103 chr11:62369870 EML3;MTA2 -0.61 -9.07 -0.63 2.25e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9952991 0.941 rs2542149 chr18:12779018 G/A cg09945482 chr18:12777974 NA 0.51 4.86 0.4 3.47e-6 Inflammatory skin disease; TGCT cis rs9549367 0.713 rs3024764 chr13:113824314 A/G cg00898013 chr13:113819073 PROZ -0.55 -7.27 -0.55 3.47e-11 Platelet distribution width; TGCT cis rs28595532 0.920 rs55671478 chr4:119753811 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs5769765 0.954 rs1569954 chr22:50244071 C/T cg22709217 chr22:50311962 ALG12;CRELD2 1.08 11.84 0.73 4.29e-22 Schizophrenia; TGCT cis rs1008375 0.932 rs4698630 chr4:17614692 C/G cg10189774 chr4:17578691 LAP3 0.65 5.49 0.44 2.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs17685 0.753 rs4728550 chr7:75670988 C/A cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7666738 0.830 rs115712871 chr4:98954535 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 0.593 rs62262730 chr3:49808274 T/G cg03034192 chr3:50606346 HEMK1;C3orf18 -0.37 -4.8 -0.4 4.56e-6 Menarche (age at onset); TGCT cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg08923669 chr16:420230 MRPL28 -0.61 -6.31 -0.49 4.44e-9 Bone mineral density (spine);Bone mineral density; TGCT trans rs1005277 0.579 rs2474575 chr10:38387901 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs910316 0.967 rs11159116 chr14:75550584 G/T cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs36051895 0.632 rs62541944 chr9:5159318 G/T cg02405213 chr9:5042618 JAK2 -0.71 -9.01 -0.63 3.02e-15 Pediatric autoimmune diseases; TGCT cis rs4780401 0.609 rs8063099 chr16:11806714 T/G cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs9906944 0.933 rs9906710 chr17:47091283 C/A cg07075026 chr17:47091521 IGF2BP1 -0.44 -4.84 -0.4 3.78e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs9388451 0.772 rs1268064 chr6:126042578 G/A cg10911889 chr6:126070802 HEY2 -0.52 -5.26 -0.43 6.17e-7 Brugada syndrome; TGCT cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs2271316 0.587 rs11078659 chr17:6903944 G/A cg21237687 chr17:6899380 ALOX12 0.42 4.59 0.38 1.06e-5 Blood metabolite levels; TGCT cis rs929354 1.000 rs1182391 chr7:157038368 T/C cg05182265 chr7:156933206 UBE3C 0.33 6.75 0.52 4.96e-10 Body mass index; TGCT cis rs9300255 0.544 rs1716157 chr12:123670473 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.69 0.46 8.5e-8 Neutrophil percentage of white cells; TGCT cis rs7267979 0.844 rs6083851 chr20:25401235 G/A cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62103177 0.525 rs4283293 chr18:77759582 A/G cg07235805 chr18:78004237 PARD6G -0.45 -4.47 -0.37 1.75e-5 Opioid sensitivity; TGCT cis rs10927875 0.632 rs6699394 chr1:16145143 C/A cg14742211 chr1:16348397 CLCNKA -0.2 -4.77 -0.39 4.99e-6 Dilated cardiomyopathy; TGCT cis rs2239547 0.618 rs1573815 chr3:52870132 A/G cg10802521 chr3:52805072 NEK4 0.57 5.54 0.45 1.75e-7 Schizophrenia; TGCT cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs6582630 0.502 rs11614397 chr12:38328163 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs9916302 0.808 rs12948906 chr17:37644854 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs7731657 0.538 rs2107335 chr5:130292853 C/A cg08523029 chr5:130500466 HINT1 -0.58 -4.84 -0.4 3.8e-6 Fasting plasma glucose; TGCT cis rs9291683 0.530 rs13115193 chr4:9982191 C/T cg11266682 chr4:10021025 SLC2A9 0.62 8.63 0.61 2.51e-14 Bone mineral density; TGCT cis rs806215 0.826 rs712699 chr7:127250597 G/A cg25922125 chr7:127225783 GCC1 0.58 5.87 0.47 3.69e-8 Type 2 diabetes; TGCT cis rs367615 0.679 rs4259216 chr5:108841817 A/G cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7666738 0.606 rs6852813 chr4:99084671 G/A cg05340658 chr4:99064831 C4orf37 0.44 4.8 0.4 4.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 1.000 rs12148786 chr15:76800362 A/G cg26408565 chr15:76604113 ETFA -0.38 -4.87 -0.4 3.28e-6 Blood metabolite levels; TGCT cis rs10037670 0.557 rs972595 chr5:153824214 G/T cg21964928 chr5:153872958 NA 0.28 5.1 0.42 1.22e-6 Behavioural disinhibition (generation interaction); TGCT cis rs4975709 0.569 rs2077269 chr5:1863506 C/T cg04156016 chr5:1868137 NA 0.34 4.79 0.4 4.64e-6 Cardiovascular disease risk factors; TGCT cis rs3924048 0.574 rs3923904 chr1:12616535 T/C cg00291366 chr1:12616550 NA 0.33 5.14 0.42 1.05e-6 Optic cup area; TGCT trans rs7819412 0.774 rs34208825 chr8:11014616 T/G cg06636001 chr8:8085503 FLJ10661 -0.77 -6.62 -0.51 9.84e-10 Triglycerides; TGCT cis rs12220898 0.749 rs7068959 chr10:50468696 A/C cg06072769 chr10:50146962 WDFY4 0.38 5.01 0.41 1.82e-6 Inflammatory biomarkers; TGCT cis rs28595532 0.920 rs28797314 chr4:119783044 A/G cg21605333 chr4:119757512 SEC24D 1.44 8.24 0.6 2.03e-13 Cannabis dependence symptom count; TGCT cis rs13256369 0.951 rs13259955 chr8:8565885 C/G cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs3806843 0.576 rs246059 chr5:140325010 G/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg04944784 chr2:26401820 FAM59B -0.77 -6.48 -0.5 1.97e-9 Gut microbiome composition (summer); TGCT cis rs9394169 0.613 rs2395399 chr6:33777432 T/C cg18005901 chr6:33739558 LEMD2 -0.52 -6.18 -0.49 8.57e-9 Essential tremor; TGCT cis rs9300255 0.602 rs1402274 chr12:123686224 T/C cg00376283 chr12:123451042 ABCB9 0.71 5.59 0.45 1.41e-7 Neutrophil percentage of white cells; TGCT cis rs6933660 0.760 rs6904364 chr6:151754273 T/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.52 -4.66 -0.39 8.03e-6 Menarche (age at onset); TGCT cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg03517284 chr6:25882590 NA -0.49 -5.07 -0.41 1.4e-6 Height; TGCT cis rs8062405 1.000 rs4788101 chr16:28867804 C/T cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9913156 0.793 rs7210953 chr17:4608870 C/T cg23387401 chr17:4582204 PELP1 0.31 4.68 0.39 7.44e-6 Lymphocyte counts; TGCT cis rs54211 1.000 rs137580 chr22:39677741 C/T cg00820535 chr22:39852281 MGAT3 0.35 5.21 0.42 7.69e-7 Sudden cardiac arrest; TGCT cis rs57221529 0.709 rs72706611 chr5:561146 C/A cg09021430 chr5:549028 NA -0.4 -5.48 -0.44 2.24e-7 Lung disease severity in cystic fibrosis; TGCT cis rs3749237 0.595 rs4855873 chr3:49459114 A/C cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs2806561 0.704 rs7532266 chr1:23551623 A/C cg12483005 chr1:23474871 LUZP1 -0.4 -4.95 -0.41 2.33e-6 Height; TGCT cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.51e-14 Type 2 diabetes; TGCT cis rs2299587 0.545 rs12543739 chr8:17756229 C/T cg01800426 chr8:17659068 MTUS1 -0.56 -5.02 -0.41 1.73e-6 Economic and political preferences; TGCT cis rs67311347 1.000 rs17078941 chr3:40450888 A/G cg13683864 chr3:40499215 RPL14 1.15 12.87 0.76 1.32e-24 Renal cell carcinoma; TGCT cis rs4319547 0.695 rs10773103 chr12:122856532 A/G cg08088222 chr12:122070432 ORAI1 -0.25 -4.49 -0.37 1.58e-5 Body mass index; TGCT cis rs4891159 0.505 rs680253 chr18:74167427 A/C cg24786174 chr18:74118243 ZNF516 -0.63 -10.94 -0.7 6.53e-20 Longevity; TGCT cis rs514406 0.825 rs6693210 chr1:53223398 A/G cg22166914 chr1:53195759 ZYG11B -0.43 -7.49 -0.56 1.13e-11 Monocyte count; TGCT cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.79e-5 Obesity-related traits; TGCT cis rs7666738 0.791 rs6532725 chr4:99061479 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4711350 0.678 rs680608 chr6:33713169 C/T cg00334056 chr6:33755658 LEMD2 0.34 4.61 0.38 9.78e-6 Schizophrenia; TGCT cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg08859206 chr1:53392774 SCP2 0.39 5.8 0.46 5.07e-8 Monocyte count; TGCT cis rs7552404 0.731 rs11161857 chr1:76370228 G/C cg22875332 chr1:76189707 ACADM 0.68 6.57 0.51 1.26e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs644799 1.000 rs593665 chr11:95574302 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.19 0.59 2.72e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9653442 0.564 rs7590378 chr2:100789877 A/G cg07810366 chr2:100720526 AFF3 -0.35 -5.26 -0.43 6e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9660180 0.620 rs3817856 chr1:1663831 C/T cg13866156 chr1:1669148 SLC35E2 0.24 5.55 0.45 1.63e-7 Body mass index; TGCT cis rs11578119 0.933 rs11584810 chr1:170471343 C/T cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg05785598 chr3:49045655 WDR6 0.36 4.78 0.39 4.78e-6 Menarche (age at onset); TGCT trans rs13064411 0.542 rs9874747 chr3:113221258 G/A cg00307254 chr3:126706825 PLXNA1 0.34 6.72 0.52 5.79e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs8177253 1.000 rs8177248 chr3:133479626 C/T cg20276088 chr3:133502917 NA -0.23 -4.44 -0.37 1.96e-5 Iron status biomarkers; TGCT cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs2455799 0.517 rs9835592 chr3:15936942 A/G cg12172478 chr3:16357591 RFTN1 -0.33 -4.81 -0.4 4.31e-6 Mean platelet volume; TGCT cis rs7914558 0.966 rs12766205 chr10:104893568 A/G cg15744005 chr10:104629667 AS3MT -0.42 -5.24 -0.43 6.69e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7617773 0.815 rs9825637 chr3:48372282 T/C cg11946769 chr3:48343235 NME6 0.8 6.88 0.53 2.61e-10 Coronary artery disease; TGCT cis rs9638182 1.000 rs35659126 chr7:72988069 C/T cg14087351 chr7:73037990 MLXIPL -0.56 -4.73 -0.39 6.08e-6 Triglycerides; TGCT cis rs2797160 1.000 rs2797161 chr6:126010789 A/G cg05901451 chr6:126070800 HEY2 0.73 6.3 0.49 4.83e-9 Endometrial cancer; TGCT cis rs77372450 0.591 rs11740603 chr5:157098756 G/T cg12606933 chr5:157078573 SOX30 -0.42 -4.72 -0.39 6.3e-6 Bipolar disorder (body mass index interaction); TGCT cis rs2657888 1.000 rs73118833 chr12:56941734 C/A cg23932658 chr12:57637574 STAC3 -0.51 -4.73 -0.39 5.9e-6 Adiponectin levels; TGCT cis rs13392177 0.672 rs4674270 chr2:219053141 G/T cg00012203 chr2:219082015 ARPC2 -0.77 -7.94 -0.58 1.04e-12 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs514406 0.621 rs2003250 chr1:53196666 T/C cg16325326 chr1:53192061 ZYG11B -0.89 -13.12 -0.76 3.31e-25 Monocyte count; TGCT cis rs1894292 0.527 rs34468776 chr4:74362504 T/A cg05868023 chr4:75230803 EREG 0.53 4.52 0.38 1.43e-5 Prostate cancer; TGCT cis rs801193 0.660 rs1962050 chr7:66240008 C/T cg18876405 chr7:65276391 NA -0.31 -4.82 -0.4 4.12e-6 Aortic root size; TGCT cis rs3820068 0.581 rs72645890 chr1:15930602 A/G cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs473651 1.000 rs473651 chr2:239335401 A/C cg18131467 chr2:239335373 ASB1 1.01 14.5 0.79 1.78e-28 Multiple system atrophy; TGCT cis rs1670533 1.000 rs11735663 chr4:1051845 C/T cg20887711 chr4:1340912 KIAA1530 0.72 5.73 0.46 7.16e-8 Recombination rate (females); TGCT cis rs2742417 1.000 rs2742397 chr3:45758946 C/G cg04837898 chr3:45731254 SACM1L 0.5 5.16 0.42 9.55e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs524281 0.861 rs535395 chr11:65906534 A/G cg00563793 chr11:65837595 PACS1 -0.56 -4.83 -0.4 3.9e-6 Electroencephalogram traits; TGCT cis rs13424612 0.965 rs58652766 chr2:240904884 G/A cg26363272 chr2:240904871 NDUFA10 0.3 4.97 0.41 2.15e-6 Odorant perception (isobutyraldehyde); TGCT cis rs1008375 0.966 rs6825133 chr4:17577776 C/T cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg04389838 chr3:44770851 ZNF501 -0.41 -5.72 -0.46 7.49e-8 Depressive symptoms; TGCT cis rs367943 1.000 rs348929 chr5:112814883 T/A cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs12579753 0.956 rs7965168 chr12:82184467 C/A cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs17030434 0.822 rs4696492 chr4:154679981 T/A cg14289246 chr4:154710475 SFRP2 0.9 7.0 0.53 1.41e-10 Electrocardiographic conduction measures; TGCT cis rs9467711 0.606 rs2073527 chr6:26374978 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9916302 0.851 rs12947620 chr17:37605364 T/C cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs2153535 0.580 rs1120392 chr6:8487053 C/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs17102423 0.755 rs7161394 chr14:65563309 G/T cg11161011 chr14:65562177 MAX -0.55 -7.7 -0.57 3.74e-12 Obesity-related traits; TGCT cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg13395646 chr4:1353034 KIAA1530 -0.4 -5.0 -0.41 1.93e-6 Obesity-related traits; TGCT cis rs4653767 1.000 rs708775 chr1:226923264 G/A cg10327440 chr1:227177885 CDC42BPA -0.47 -5.22 -0.42 7.27e-7 Parkinson's disease; TGCT cis rs4808199 0.948 rs2301668 chr19:19452249 G/A cg03709012 chr19:19516395 GATAD2A 0.81 6.32 0.49 4.32e-9 Nonalcoholic fatty liver disease; TGCT cis rs58722170 0.659 rs61776209 chr1:38090323 C/T cg17933807 chr1:38061675 GNL2 -0.87 -8.9 -0.62 5.71e-15 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7552404 0.883 rs7513363 chr1:76143443 A/G cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6728642 0.908 rs9973669 chr2:97679094 T/C cg26665480 chr2:98280029 ACTR1B -0.95 -5.88 -0.47 3.52e-8 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs7523050 0.643 rs34114412 chr1:109402866 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs2327429 0.767 rs12190287 chr6:134214525 C/G cg08368617 chr6:134217040 NA -0.45 -4.57 -0.38 1.17e-5 Coronary artery disease; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg11905131 chr22:24372483 LOC391322 0.88 8.52 0.61 4.62e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6598955 0.671 rs12145403 chr1:26597189 C/T cg14788334 chr1:26606110 SH3BGRL3 0.24 4.61 0.38 9.71e-6 Obesity-related traits; TGCT cis rs3806843 0.735 rs3776129 chr5:140072292 G/A cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs11098499 0.954 rs10034623 chr4:120397829 G/A cg09307838 chr4:120376055 NA 0.72 7.08 0.54 9.22e-11 Corneal astigmatism; TGCT cis rs9926296 0.643 rs12596429 chr16:89841374 T/C cg26513180 chr16:89883248 FANCA 0.72 7.03 0.53 1.24e-10 Vitiligo; TGCT cis rs875971 0.895 rs3857684 chr7:65938158 G/C cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.1e-6 Aortic root size; TGCT cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg07061783 chr6:25882402 NA -0.66 -6.91 -0.53 2.2e-10 Blood metabolite levels; TGCT cis rs3812831 0.630 rs9562129 chr13:114917152 A/G cg06611532 chr13:114900021 NA 0.34 6.0 0.47 2.04e-8 Schizophrenia; TGCT cis rs13191362 1.000 rs35723993 chr6:163008197 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs57590327 0.503 rs9880844 chr3:81507217 C/T cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs6725041 0.819 rs1521660 chr2:213082960 C/T cg16329650 chr2:213403929 ERBB4 -0.54 -4.64 -0.38 8.57e-6 QT interval (ambient particulate matter interaction); TGCT cis rs2629540 0.737 rs10901821 chr10:126480556 T/C cg08799069 chr10:126477246 METTL10 -0.3 -4.83 -0.4 4e-6 Cocaine dependence; TGCT cis rs6582630 0.533 rs11504406 chr12:38334580 C/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs7819412 0.775 rs4841489 chr8:10936811 A/G cg21775007 chr8:11205619 TDH -0.5 -4.61 -0.38 9.83e-6 Triglycerides; TGCT cis rs6545977 0.692 rs58235267 chr2:63277843 C/G cg17519650 chr2:63277830 OTX1 0.73 8.01 0.58 7.03e-13 Prostate cancer; TGCT cis rs7572733 0.555 rs7561950 chr2:198754244 C/T cg00792783 chr2:198669748 PLCL1 0.57 5.11 0.42 1.2e-6 Dermatomyositis; TGCT cis rs9914544 0.545 rs3803835 chr17:18793061 C/T cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs875971 0.965 rs28682868 chr7:65689809 C/T cg11764359 chr7:65958608 NA -0.61 -5.52 -0.44 1.93e-7 Aortic root size; TGCT cis rs5750830 0.649 rs4821894 chr22:39809820 G/C cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.790 rs13195402 chr6:26463575 G/T cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs789852 0.764 rs2794668 chr3:194316895 C/T cg18000598 chr3:194342907 TMEM44 -0.76 -5.09 -0.42 1.31e-6 QT interval; TGCT cis rs2639990 1.000 rs609303 chr18:72895242 C/T cg02750262 chr18:72916776 ZADH2 0.87 6.6 0.51 1.08e-9 Vascular endothelial growth factor levels; TGCT cis rs7917772 0.636 rs7894154 chr10:104524647 G/A cg05855489 chr10:104503620 C10orf26 0.67 5.32 0.43 4.77e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1538970 1.000 rs4520450 chr1:45834773 A/G cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs7267979 0.744 rs6050464 chr20:25209299 C/A cg03522245 chr20:25566470 NINL 0.56 5.63 0.45 1.13e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 0.932 rs449703 chr20:25458559 C/T cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs17206232 0.534 rs6877731 chr5:64695717 C/T cg12806353 chr3:119315532 PLA1A 0.45 6.98 0.53 1.58e-10 Schizophrenia; TGCT trans rs208520 0.690 rs10455595 chr6:66738034 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs9300255 0.537 rs2695482 chr12:123623174 C/T cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs35828350 1 rs35828350 chr15:85355841 G/A cg11189052 chr15:85197271 WDR73 0.71 5.88 0.47 3.62e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs9859260 0.744 rs492349 chr3:195784192 G/A cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs9300255 0.596 rs4460848 chr12:123677810 A/G cg00376283 chr12:123451042 ABCB9 0.79 6.75 0.52 5e-10 Neutrophil percentage of white cells; TGCT cis rs7607369 0.580 rs17573731 chr2:219652153 T/C cg02176678 chr2:219576539 TTLL4 -0.45 -5.86 -0.47 3.89e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg03264133 chr6:25882463 NA 0.74 7.71 0.57 3.43e-12 Blood metabolite levels; TGCT cis rs9894429 1.000 rs7503679 chr17:79583843 G/C cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs763014 0.966 rs12935215 chr16:670605 T/C cg00908189 chr16:619842 PIGQ 0.87 10.65 0.69 3.27e-19 Height; TGCT cis rs5769765 0.778 rs8137331 chr22:50313358 G/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.19 -12.02 -0.73 1.56e-22 Schizophrenia; TGCT cis rs10779751 0.770 rs6674994 chr1:11239515 T/C cg08854313 chr1:11322531 MTOR 0.84 8.09 0.59 4.52e-13 Body mass index; TGCT cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2235642 0.717 rs9937922 chr16:1658154 C/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.29 -4.95 -0.41 2.38e-6 Coronary artery disease; TGCT cis rs910316 0.967 rs12147532 chr14:75651858 T/G cg08847533 chr14:75593920 NEK9 -0.91 -9.56 -0.65 1.46e-16 Height; TGCT cis rs9640161 0.830 rs13307276 chr7:150061525 T/C cg21361702 chr7:150065534 REPIN1 0.49 4.47 0.37 1.75e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg08392591 chr16:89556376 ANKRD11 0.61 5.78 0.46 5.71e-8 Multiple myeloma (IgH translocation); TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT trans rs6951245 0.554 rs35126802 chr7:1134842 C/T cg13565492 chr6:43139072 SRF -0.82 -7.72 -0.57 3.43e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs9325144 0.600 rs34138871 chr12:38735261 A/G cg26384229 chr12:38710491 ALG10B 0.61 5.65 0.45 1.05e-7 Morning vs. evening chronotype; TGCT cis rs11098499 0.863 rs10018280 chr4:120478139 T/G cg09307838 chr4:120376055 NA 0.74 7.34 0.55 2.49e-11 Corneal astigmatism; TGCT cis rs2019137 0.868 rs3748916 chr2:113984033 C/T cg27425262 chr2:113953981 PSD4;LOC440839 -0.47 -6.82 -0.52 3.64e-10 Lymphocyte counts; TGCT cis rs748404 0.578 rs2278856 chr15:43631356 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.46 4.44 0.37 1.98e-5 Lung cancer; TGCT cis rs9549260 0.755 rs7338669 chr13:41200091 C/T cg21288729 chr13:41239152 FOXO1 -0.98 -10.52 -0.69 6.96e-19 Red blood cell count; TGCT cis rs6543140 0.964 rs13383602 chr2:103085962 C/T cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs9527 0.590 rs943039 chr10:104825132 C/T cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs6940638 1.000 rs12215241 chr6:27023081 G/A cg16898833 chr6:26189333 HIST1H4D 0.77 5.68 0.45 8.91e-8 Intelligence (multi-trait analysis); TGCT cis rs73198271 0.628 rs56188408 chr8:8592158 G/C ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs3813567 0.702 rs7164665 chr15:78953919 T/C cg24631222 chr15:78858424 CHRNA5 0.68 4.72 0.39 6.35e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs9604529 0.557 rs74406200 chr13:114741208 C/T cg13259177 chr13:114761607 RASA3 -0.27 -4.54 -0.38 1.32e-5 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs6500602 0.727 rs2160567 chr16:4535557 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.29 5.35 0.43 4.12e-7 Schizophrenia; TGCT cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs7617773 0.710 rs36064160 chr3:48243101 C/G cg11946769 chr3:48343235 NME6 0.76 6.53 0.51 1.54e-9 Coronary artery disease; TGCT cis rs9902453 0.967 rs7212741 chr17:28322941 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 6.55 0.51 1.36e-9 Coffee consumption (cups per day); TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg04234412 chr22:24373322 LOC391322 -0.88 -8.35 -0.6 1.17e-13 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7044106 0.762 rs1158553 chr9:123400974 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.45 4.87 0.4 3.3e-6 Hip circumference adjusted for BMI; TGCT cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs6964587 1.000 rs6979085 chr7:91673623 C/T cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg05738196 chr6:26577821 NA 0.87 11.1 0.71 2.65e-20 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg03806693 chr22:41940476 POLR3H 1.14 12.91 0.76 1.07e-24 Vitiligo; TGCT cis rs1697139 0.583 rs11960733 chr5:66538715 C/T cg11553311 chr5:66541588 NA 0.3 6.4 0.5 2.84e-9 Breast cancer; TGCT cis rs2456568 0.803 rs10831142 chr11:93640781 A/G cg16099599 chr11:93583650 C11orf90 0.42 5.4 0.44 3.24e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg24549020 chr5:56110836 MAP3K1 0.67 5.73 0.46 7.1e-8 Type 2 diabetes; TGCT cis rs11098499 0.955 rs1551 chr4:120158500 T/G cg24670566 chr4:120433619 PDE5A 0.23 4.45 0.37 1.89e-5 Corneal astigmatism; TGCT cis rs4285028 0.747 rs9808981 chr3:121429561 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs7582180 0.629 rs6716636 chr2:100940067 C/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1552244 0.572 rs3894323 chr3:10168967 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.967 rs1535276 chr6:26520941 T/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs765787 0.530 rs1648285 chr15:45517505 C/G cg24006582 chr15:45444508 DUOX1 -0.26 -5.7 -0.46 8.11e-8 Uric acid levels; TGCT cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg03236948 chr11:63997492 DNAJC4 0.37 4.67 0.39 7.66e-6 Platelet count; TGCT cis rs910316 1.000 rs4899544 chr14:75546556 C/T cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg13699009 chr12:122356056 WDR66 0.28 6.14 0.48 1.05e-8 Mean corpuscular volume; TGCT cis rs4654899 0.965 rs4654907 chr1:21521094 C/T cg01072550 chr1:21505969 NA -0.5 -8.03 -0.59 6.27e-13 Superior frontal gyrus grey matter volume; TGCT cis rs2242194 0.816 rs11264296 chr1:154994750 T/C cg12436631 chr1:155007014 DCST1;DCST2 0.26 7.04 0.53 1.16e-10 Schizophrenia; TGCT cis rs11098499 0.691 rs9996644 chr4:120238877 G/T cg09307838 chr4:120376055 NA 0.63 6.14 0.48 1.01e-8 Corneal astigmatism; TGCT cis rs17345786 0.628 rs11718446 chr3:101552553 C/T cg11279151 chr3:101281821 RG9MTD1 -0.36 -7.75 -0.57 2.86e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9467711 0.606 rs12174623 chr6:26373086 C/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs13191362 1.000 rs73035023 chr6:163000927 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg20891558 chr2:74357851 NA 0.59 8.97 0.63 3.96e-15 Gestational age at birth (maternal effect); TGCT cis rs2456568 0.803 rs10765641 chr11:93640312 T/C cg26875233 chr11:93583750 C11orf90 -0.48 -6.35 -0.5 3.73e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4563143 0.704 rs16961809 chr19:29226299 C/T cg12667521 chr19:29218732 NA 0.53 6.34 0.49 3.83e-9 Methadone dose in opioid dependence; TGCT cis rs12478296 1.000 rs73007129 chr2:243000555 T/C cg06360820 chr2:242988706 NA -0.79 -5.2 -0.42 7.9e-7 Obesity-related traits; TGCT cis rs78487399 0.808 rs111812200 chr2:43674278 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.09 -0.42 1.3e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3096299 0.933 rs889576 chr16:89429653 A/G cg06640241 chr16:89574553 SPG7 -0.57 -5.62 -0.45 1.21e-7 Multiple myeloma (IgH translocation); TGCT cis rs7547997 0.615 rs34591069 chr1:158316990 G/C cg03528325 chr1:158223921 CD1A 0.33 4.81 0.4 4.38e-6 QRS duration; TGCT cis rs10851411 0.908 rs12324717 chr15:42846553 C/A cg23803468 chr15:43513504 EPB42 0.27 5.16 0.42 9.47e-7 Glucose homeostasis traits; TGCT cis rs56235845 0.964 rs11746443 chr5:176798306 G/A cg06060754 chr5:176797920 RGS14 0.62 10.78 0.7 1.58e-19 Hemoglobin concentration;Hematocrit; TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg24675658 chr1:53192096 ZYG11B -0.69 -8.17 -0.59 3.05e-13 Monocyte count; TGCT cis rs35146811 0.735 rs1061230 chr7:99807265 G/A cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg21016266 chr12:122356598 WDR66 0.43 5.65 0.45 1.03e-7 Mean corpuscular volume; TGCT cis rs9659323 0.931 rs113197996 chr1:119522426 G/A cg07961512 chr1:119535619 NA 0.44 4.99 0.41 2.01e-6 Body mass index; TGCT cis rs2688608 0.592 rs3933085 chr10:75483331 C/T cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs17152411 0.947 rs17152408 chr10:126649007 C/T cg07906193 chr10:126599966 NA 0.37 4.72 0.39 6.35e-6 Height; TGCT cis rs2224391 0.578 rs766339 chr6:5243506 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs929354 0.713 rs1034785 chr7:157002383 T/C cg05182265 chr7:156933206 UBE3C -0.38 -8.68 -0.61 1.92e-14 Body mass index; TGCT cis rs782590 0.537 rs12619903 chr2:55884106 T/A cg03859395 chr2:55845619 SMEK2 -0.64 -5.17 -0.42 9.11e-7 Metabolic syndrome; TGCT cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg17554472 chr22:41940697 POLR3H -0.47 -4.89 -0.4 3.06e-6 Vitiligo; TGCT cis rs1008375 1.000 rs6849704 chr4:17652031 G/C cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7104764 0.957 rs519592 chr11:236811 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.13 13.04 0.76 5.36e-25 Menarche (age at onset); TGCT cis rs2251381 0.750 rs2255055 chr21:30537045 C/T cg24692254 chr21:30365293 RNF160 0.71 6.98 0.53 1.56e-10 Selective IgA deficiency; TGCT cis rs2836950 0.565 rs7278297 chr21:40625752 A/C cg11890956 chr21:40555474 PSMG1 -0.69 -6.81 -0.52 3.7e-10 Menarche (age at onset); TGCT cis rs709400 0.663 rs3742458 chr14:103950368 A/G cg12935359 chr14:103987150 CKB -0.36 -5.64 -0.45 1.11e-7 Body mass index; TGCT cis rs1532993 0.518 rs10513769 chr4:98595395 G/C cg05340658 chr4:99064831 C4orf37 -0.38 -4.49 -0.37 1.59e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs986417 0.818 rs767602 chr14:61098624 G/T cg27398547 chr14:60952738 C14orf39 1.48 8.31 0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs933688 1.000 rs2059208 chr5:90732065 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.05 10.44 0.68 1.07e-18 Smoking behavior; TGCT cis rs7824557 0.670 rs2736381 chr8:11132766 A/T cg21775007 chr8:11205619 TDH -0.5 -4.51 -0.38 1.48e-5 Retinal vascular caliber; TGCT cis rs13082711 0.519 rs13091109 chr3:27229125 G/A cg02860705 chr3:27208620 NA 0.43 6.88 0.53 2.58e-10 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs9467773 1.000 rs2224380 chr6:26553943 G/A cg15659132 chr6:26577336 NA 0.89 13.14 0.76 3.05e-25 Intelligence (multi-trait analysis); TGCT cis rs57920188 0.703 rs3813810 chr1:4088339 G/T cg20703997 chr1:4087676 NA 0.46 4.98 0.41 2.09e-6 Interleukin-17 levels; TGCT cis rs2442825 0.508 rs2648545 chr3:9389223 C/T cg24633833 chr3:10029261 TMEM111 -0.53 -5.16 -0.42 9.7e-7 Cerebrospinal fluid clusterin levels; TGCT cis rs3008870 0.583 rs2815369 chr1:67500894 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.97 8.09 0.59 4.6e-13 Lymphocyte percentage of white cells; TGCT cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg22920501 chr2:26401640 FAM59B -0.78 -6.16 -0.48 9.43e-9 Gut microbiome composition (summer); TGCT cis rs586688 1.000 rs492563 chr1:201631471 C/T cg14168733 chr1:201708718 NAV1 -0.54 -4.52 -0.38 1.43e-5 Obesity-related traits; TGCT trans rs7726839 0.540 rs58599998 chr5:596087 A/G cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs7945705 0.935 rs2653593 chr11:8877317 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -5.62 -0.45 1.21e-7 Hemoglobin concentration; TGCT cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs116975820 0.698 rs11181497 chr12:42814962 A/G cg19980929 chr12:42632907 YAF2 0.6 4.82 0.4 4.14e-6 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs7264396 0.790 rs3787166 chr20:34229072 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.52 -0.38 1.44e-5 Total cholesterol levels; TGCT cis rs2535633 0.631 rs11915851 chr3:53096047 C/T cg11645453 chr3:52864694 ITIH4 0.27 5.19 0.42 8.41e-7 Body mass index; TGCT cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg21951975 chr1:209979733 IRF6 0.66 5.69 0.45 8.77e-8 Cleft lip with or without cleft palate; TGCT cis rs9902453 0.791 rs3115086 chr17:28025949 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.85 8.57 0.61 3.4e-14 Coffee consumption (cups per day); TGCT cis rs2303745 0.589 rs8103523 chr19:17398269 A/G cg04248312 chr19:17393744 ANKLE1 -0.34 -5.59 -0.45 1.35e-7 Systemic lupus erythematosus; TGCT cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg19318889 chr4:1322082 MAEA 0.29 6.6 0.51 1.06e-9 Longevity; TGCT cis rs12497850 0.931 rs4974082 chr3:48999323 G/A cg18654377 chr3:49208889 KLHDC8B -0.42 -5.46 -0.44 2.48e-7 Parkinson's disease; TGCT cis rs1580019 0.510 rs4723162 chr7:32543804 C/A cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.11 0.79 1.45e-27 Cognitive ability; TGCT cis rs10114408 0.918 rs10992952 chr9:96645436 T/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT trans rs561341 0.843 rs879945 chr17:30242796 G/A cg20587970 chr11:113659929 NA -0.86 -11.09 -0.71 2.74e-20 Hip circumference adjusted for BMI; TGCT trans rs7698623 0.850 rs4693891 chr4:88787834 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg08736216 chr1:53307985 ZYG11A -0.3 -6.06 -0.48 1.48e-8 Monocyte count; TGCT cis rs7027203 0.828 rs10821229 chr9:96595136 A/C cg13679303 chr9:96623674 NA -0.66 -10.78 -0.7 1.64e-19 DNA methylation (variation); TGCT cis rs9650657 0.645 rs11774552 chr8:10515679 C/T cg27411982 chr8:10470053 RP1L1 -0.23 -4.93 -0.4 2.62e-6 Neuroticism; TGCT cis rs1525293 0.714 rs12698979 chr7:70506630 A/T cg21135135 chr7:70597687 WBSCR17 -0.47 -4.66 -0.39 7.9e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs7412746 0.611 rs1889741 chr1:150869045 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs6845621 0.840 rs6816238 chr4:18918968 T/C cg12196642 chr4:18937545 NA -0.24 -4.45 -0.37 1.91e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs1577917 0.917 rs1838959 chr6:86556804 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs7582180 0.629 rs11686649 chr2:100946701 T/C cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.572 rs28446104 chr8:8795901 C/G cg15556689 chr8:8085844 FLJ10661 -0.68 -5.91 -0.47 3.04e-8 Mood instability; TGCT cis rs8017423 0.967 rs7147809 chr14:90715025 A/G cg04374321 chr14:90722782 PSMC1 0.74 7.74 0.57 2.98e-12 Mortality in heart failure; TGCT cis rs939658 0.728 rs8031638 chr15:79422726 C/T cg17916960 chr15:79447300 NA -0.48 -6.69 -0.52 6.71e-10 Refractive error; TGCT cis rs17739794 0.677 rs17739674 chr8:801584 G/T cg20652464 chr8:752313 NA -0.24 -4.59 -0.38 1.08e-5 Clozapine-induced cytotoxicity; TGCT cis rs644799 0.710 rs10831427 chr11:95508383 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.81 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs231513 1.000 rs231518 chr17:41961451 C/T cg26893861 chr17:41843967 DUSP3 0.72 5.31 0.43 4.91e-7 Cognitive function; TGCT cis rs2439831 0.850 rs7169988 chr15:44060435 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.93 0.47 2.78e-8 Lung cancer in ever smokers; TGCT cis rs2486288 0.656 rs7171312 chr15:45570225 C/G cg14582100 chr15:45693742 SPATA5L1 -0.43 -4.86 -0.4 3.48e-6 Glomerular filtration rate; TGCT cis rs9653442 0.527 rs2118280 chr2:100746395 G/A cg22139774 chr2:100720529 AFF3 -0.37 -5.48 -0.44 2.24e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs514833 chr11:68657734 C/T cg21862992 chr11:68658383 NA 0.47 6.54 0.51 1.42e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs950169 0.881 rs62029599 chr15:84956565 A/C cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT trans rs1496653 0.602 rs13082311 chr3:23600011 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs9486719 1.000 rs1303852 chr6:96864523 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs6964587 0.967 rs7783414 chr7:91785957 C/T cg17063962 chr7:91808500 NA 0.89 9.55 0.65 1.53e-16 Breast cancer; TGCT cis rs981844 0.735 rs111822747 chr4:154734629 G/C cg14289246 chr4:154710475 SFRP2 1.01 8.88 0.62 6.23e-15 Response to statins (LDL cholesterol change); TGCT trans rs6089829 0.962 rs3899032 chr20:61658542 G/A cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9303401 0.614 rs3887355 chr17:56538639 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.77 0.52 4.6e-10 Cognitive test performance; TGCT cis rs3026101 0.624 rs1058400 chr17:5288794 G/C cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.92 0.4 2.73e-6 Body mass index; TGCT cis rs4746818 1.000 rs10823301 chr10:70885875 G/A cg11621586 chr10:70884670 VPS26A 1.16 10.93 0.7 6.81e-20 Left atrial antero-posterior diameter; TGCT cis rs12210905 0.688 rs12209905 chr6:27404592 C/G cg08851530 chr6:28072375 NA 1.34 6.07 0.48 1.44e-8 Hip circumference adjusted for BMI; TGCT cis rs11690935 0.843 rs9784123 chr2:172785005 T/A cg13550731 chr2:172543902 DYNC1I2 -0.86 -7.68 -0.57 4.12e-12 Schizophrenia; TGCT cis rs875971 1.000 rs6956179 chr7:65806659 C/T cg11764359 chr7:65958608 NA -0.63 -5.8 -0.46 5.13e-8 Aortic root size; TGCT cis rs806215 0.526 rs12673293 chr7:127520162 T/G cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.46e-6 Type 2 diabetes; TGCT cis rs1953600 1.000 rs2789679 chr10:81907884 A/T cg04850286 chr10:81895943 PLAC9 -0.4 -4.72 -0.39 6.32e-6 Sarcoidosis; TGCT cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.45 4.71 0.39 6.41e-6 Lymphocyte counts; TGCT cis rs7647973 0.626 rs4855833 chr3:49657441 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs12477438 0.501 rs12992218 chr2:99753834 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs7216064 0.911 rs12449442 chr17:65947640 G/A cg12091567 chr17:66097778 LOC651250 -0.82 -6.18 -0.49 8.44e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9902453 0.808 rs10445400 chr17:28183059 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 6.96 0.53 1.75e-10 Coffee consumption (cups per day); TGCT cis rs13185784 0.667 rs4700728 chr5:179647551 T/G cg04734276 chr5:178882605 NA 0.29 4.46 0.37 1.79e-5 TRAIL levels; TGCT cis rs6952808 0.862 rs4721135 chr7:1912222 A/G cg22963979 chr7:1858916 MAD1L1 -0.34 -5.03 -0.41 1.7e-6 Bipolar disorder and schizophrenia; TGCT cis rs7552404 0.731 rs10873788 chr1:76367857 A/C cg03433033 chr1:76189801 ACADM 0.69 6.46 0.5 2.1e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg00343986 chr7:65444356 GUSB 0.22 5.38 0.44 3.58e-7 Calcium levels; TGCT cis rs7917772 0.636 rs2486757 chr10:104535145 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.58 4.77 0.39 5.02e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2735413 0.564 rs1882595 chr16:78100684 G/A cg09132178 chr16:78079569 NA 0.36 4.85 0.4 3.64e-6 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs13326165 0.760 rs34762015 chr3:52366044 G/A cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.2e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6754311 0.593 rs313524 chr2:136444123 C/T cg07169764 chr2:136633963 MCM6 0.69 6.28 0.49 5.13e-9 Mosquito bite size; TGCT cis rs7666738 0.519 rs11732209 chr4:98801643 A/G cg17366294 chr4:99064904 C4orf37 0.61 5.71 0.46 8.05e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6831352 0.918 rs7694646 chr4:100059732 T/A cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs9611565 0.592 rs4481089 chr22:41980892 T/C cg17554472 chr22:41940697 POLR3H -0.49 -5.15 -0.42 9.88e-7 Vitiligo; TGCT cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.6 6.44 0.5 2.39e-9 Height; TGCT cis rs12519773 0.501 rs4293897 chr5:92500822 T/G cg04854328 chr5:92914828 FLJ42709 -0.3 -4.55 -0.38 1.24e-5 Migraine; TGCT cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg09222892 chr1:25734099 RHCE 0.44 7.12 0.54 7.87e-11 Erythrocyte sedimentation rate; TGCT cis rs3751972 0.668 rs4796228 chr17:26222810 A/G cg02948944 chr17:26242737 NA -0.35 -5.14 -0.42 1.05e-6 Fractional exhaled nitric oxide (childhood); TGCT cis rs11190604 1.000 rs2495752 chr10:102326115 T/C cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.18e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs73198271 0.694 rs115037021 chr8:8647080 A/C cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2227564 0.620 rs10740418 chr10:75519322 T/C cg04320760 chr10:75533139 FUT11 -0.32 -4.55 -0.38 1.28e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9457247 1.000 rs239935 chr6:167411788 G/A cg23791538 chr6:167370224 RNASET2 -0.52 -5.15 -0.42 1e-6 Crohn's disease; TGCT cis rs11623869 0.614 rs11627052 chr14:103863476 A/G cg12935359 chr14:103987150 CKB 0.45 5.95 0.47 2.55e-8 Bone mineral density; TGCT cis rs7666738 0.830 rs28417577 chr4:99053007 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12472274 0.941 rs12616232 chr2:239080093 C/T cg17459225 chr2:239074497 NA 0.32 4.61 0.38 9.9e-6 Phospholipid levels (plasma); TGCT cis rs11671005 0.570 rs73062110 chr19:58936642 G/T cg13877915 chr19:58951672 ZNF132 0.64 5.12 0.42 1.13e-6 Mean platelet volume; TGCT cis rs13256369 0.755 rs12550057 chr8:8562268 G/A cg17143192 chr8:8559678 CLDN23 0.54 5.06 0.41 1.47e-6 Obesity-related traits; TGCT cis rs853679 0.517 rs9368556 chr6:28131153 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs2147959 0.824 rs1925730 chr1:228666410 G/A cg22700015 chr1:228743131 NA -0.62 -4.67 -0.39 7.73e-6 Adult asthma; TGCT cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg05025164 chr4:1340916 KIAA1530 0.51 4.58 0.38 1.12e-5 Longevity; TGCT cis rs1784581 0.588 rs6415086 chr6:162418147 C/T cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs72634258 0.554 rs4908699 chr1:7905274 G/A cg26816564 chr1:7831052 VAMP3 0.87 6.44 0.5 2.34e-9 Inflammatory bowel disease; TGCT cis rs10791097 0.694 rs1054869 chr11:130742630 G/A cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7647973 0.925 rs4384984 chr3:49289878 T/G cg05785598 chr3:49045655 WDR6 0.39 4.61 0.38 9.91e-6 Menarche (age at onset); TGCT cis rs9534288 0.833 rs56813530 chr13:46622039 A/C cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs1577917 0.958 rs12213343 chr6:86443019 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.17 -0.42 9.02e-7 Response to antipsychotic treatment; TGCT cis rs7824557 0.736 rs10107010 chr8:11132712 C/A cg21775007 chr8:11205619 TDH -0.6 -5.74 -0.46 6.84e-8 Retinal vascular caliber; TGCT cis rs12681288 0.862 rs7015529 chr8:1020249 A/G cg04851639 chr8:1020857 NA -0.37 -6.83 -0.52 3.45e-10 Schizophrenia; TGCT cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg26119090 chr2:26468346 HADHA;HADHB -0.92 -6.8 -0.52 3.96e-10 Gut microbiome composition (summer); TGCT cis rs4851266 0.865 rs11123818 chr2:100867308 G/A cg22139774 chr2:100720529 AFF3 -0.32 -4.66 -0.39 7.89e-6 Educational attainment; TGCT cis rs4819052 0.851 rs9977178 chr21:46664531 G/T cg06618935 chr21:46677482 NA -0.37 -5.83 -0.46 4.48e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg21672276 chr3:44754072 ZNF502 -0.46 -5.2 -0.42 8.15e-7 Depressive symptoms; TGCT cis rs3960554 0.808 rs111714534 chr7:75748896 C/T cg17325771 chr7:75508891 RHBDD2 -0.54 -4.63 -0.38 8.97e-6 Eotaxin levels; TGCT cis rs1062177 0.826 rs2915873 chr5:151156658 G/A cg12924095 chr5:151150029 G3BP1 0.35 4.99 0.41 2.03e-6 Preschool internalizing problems; TGCT cis rs6582630 0.638 rs12425531 chr12:38550387 A/G cg26384229 chr12:38710491 ALG10B -0.53 -4.77 -0.39 5.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs79387448 0.745 rs1403549 chr2:103110745 G/C cg09003973 chr2:102972529 NA 0.85 5.65 0.45 1.03e-7 Gut microbiota (bacterial taxa); TGCT cis rs6490294 0.748 rs7963329 chr12:112403931 A/G cg10833066 chr12:111807467 FAM109A 0.37 5.45 0.44 2.57e-7 Mean platelet volume; TGCT cis rs73058052 0.542 rs10414643 chr19:50097784 T/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.65 5.15 0.42 1.01e-6 Fibrinogen levels; TGCT cis rs9733 0.566 rs112967224 chr1:150677263 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.49 0.37 1.63e-5 Tonsillectomy; TGCT trans rs916888 0.610 rs199536 chr17:44820425 T/C cg22968622 chr17:43663579 NA -0.99 -9.47 -0.65 2.39e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs597539 0.652 rs501799 chr11:68631240 G/T cg04772025 chr11:68637568 NA 0.58 6.69 0.52 6.78e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4073582 0.595 rs3016319 chr11:65981846 C/T cg16950941 chr11:66035639 RAB1B 0.56 5.21 0.42 7.62e-7 Gout; TGCT cis rs72627509 0.629 rs1277313 chr4:57903948 A/C cg26694713 chr4:57773883 REST -0.59 -5.14 -0.42 1.04e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1862618 0.671 rs2591957 chr5:56243146 A/T cg20203395 chr5:56204925 C5orf35 0.51 4.73 0.39 5.91e-6 Initial pursuit acceleration; TGCT cis rs2439831 0.681 rs3742971 chr15:43622916 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.99 -8.47 -0.61 5.98e-14 Lung cancer in ever smokers; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg24846343 chr22:24311635 DDTL 0.22 5.68 0.45 9.16e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1008375 0.900 rs7658447 chr4:17579415 T/C cg10189774 chr4:17578691 LAP3 0.61 5.15 0.42 9.88e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9325144 0.560 rs10876005 chr12:39126149 C/G cg13010199 chr12:38710504 ALG10B -0.56 -5.01 -0.41 1.82e-6 Morning vs. evening chronotype; TGCT cis rs9393777 0.513 rs9368451 chr6:26654333 A/G cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs1215050 0.791 rs13114823 chr4:98671119 G/A cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs250677 0.687 rs171636 chr5:148434545 G/A cg23229984 chr5:148520753 ABLIM3 0.23 5.1 0.42 1.25e-6 Breast cancer; TGCT cis rs2075371 1.000 rs2241335 chr7:133979368 C/T cg11752832 chr7:134001865 SLC35B4 0.68 6.35 0.5 3.76e-9 Mean platelet volume; TGCT cis rs736408 0.677 rs1042779 chr3:52821011 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.57 5.28 0.43 5.67e-7 Bipolar disorder; TGCT cis rs7208859 0.673 rs9891179 chr17:29208160 G/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7929679 0.875 rs11032876 chr11:34813868 C/A cg18414381 chr11:34642885 EHF -0.23 -4.51 -0.38 1.47e-5 Chronic obstructive pulmonary disease-related biomarkers;Lung disease severity in cystic fibrosis; TGCT cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg17971929 chr21:40555470 PSMG1 -0.68 -5.96 -0.47 2.42e-8 Cognitive function; TGCT cis rs2948294 0.524 rs13270062 chr8:8112650 C/A cg06636001 chr8:8085503 FLJ10661 0.82 7.16 0.54 6.3e-11 Red cell distribution width; TGCT cis rs1385374 0.858 rs3765107 chr12:129278310 A/G cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs10504229 0.636 rs10958525 chr8:58051528 C/A cg08280861 chr8:58055591 NA 0.4 5.48 0.44 2.3e-7 Developmental language disorder (linguistic errors); TGCT cis rs6912958 0.559 rs376633 chr6:88042785 T/C cg08069147 chr6:88032118 GJB7;C6orf162 0.73 7.63 0.57 5.25e-12 Monocyte percentage of white cells; TGCT cis rs2717559 0.504 rs2585130 chr8:143868977 T/C cg07661805 chr8:143867942 LY6D 0.23 4.47 0.37 1.77e-5 Urinary tract infection frequency; TGCT cis rs5167 0.781 rs11672748 chr19:45490192 A/G cg13119609 chr19:45449297 APOC2 0.23 4.73 0.39 5.98e-6 Blood protein levels; TGCT cis rs763014 0.932 rs2269560 chr16:682442 A/C cg07343612 chr16:622815 PIGQ -0.42 -8.45 -0.6 6.8e-14 Height; TGCT cis rs634534 0.591 rs688862 chr11:65733393 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.58 5.46 0.44 2.55e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs916888 0.610 rs199442 chr17:44820122 G/A cg17911788 chr17:44343683 NA -0.5 -5.73 -0.46 7.23e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4389656 0.806 rs897710 chr5:6762770 C/T cg12187999 chr5:6845652 NA 0.32 4.45 0.37 1.85e-5 Coronary artery disease; TGCT cis rs6951245 0.935 rs11763765 chr7:1060510 C/T cg03188948 chr7:1209495 NA 0.55 4.56 0.38 1.2e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs10927875 0.688 rs2009371 chr1:16348083 A/T cg21385522 chr1:16154831 NA 0.62 6.41 0.5 2.76e-9 Dilated cardiomyopathy; TGCT cis rs7208859 0.673 rs216409 chr17:28906269 C/T cg04154034 chr17:28927549 LRRC37B2 -0.77 -4.81 -0.4 4.37e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs5769765 1.000 rs8138941 chr22:50290678 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs2562456 0.874 rs9304986 chr19:21682062 G/A cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs1371867 0.846 rs1692007 chr8:101268343 T/C cg06636551 chr8:101224915 SPAG1 0.43 5.95 0.47 2.58e-8 Atrioventricular conduction; TGCT cis rs7772486 0.754 rs6915718 chr6:146100676 A/G cg05347473 chr6:146136440 FBXO30 -0.54 -5.1 -0.42 1.25e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2224391 0.540 rs1570085 chr6:5253063 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -0.99 -6.43 -0.5 2.46e-9 Height; TGCT cis rs6674970 0.933 rs12134957 chr1:151045419 A/G cg00003202 chr1:151319512 RFX5 -0.53 -4.62 -0.38 9.6e-6 Childhood ear infection; TGCT cis rs7843479 0.582 rs13439690 chr8:21778082 T/C cg17168535 chr8:21777572 XPO7 0.82 8.19 0.59 2.68e-13 Mean corpuscular volume; TGCT cis rs2288884 0.767 rs3450 chr19:52552999 T/C cg15405931 chr19:52693188 PPP2R1A -0.64 -4.5 -0.38 1.51e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs981844 0.775 rs17299519 chr4:154762123 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.89 0.62 5.85e-15 Response to statins (LDL cholesterol change); TGCT cis rs3772130 0.962 rs13065245 chr3:121566729 C/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs858239 0.571 rs2390755 chr7:23190716 A/T cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7226408 0.842 rs62083182 chr18:34339924 A/C cg06757138 chr18:34340585 FHOD3 0.29 4.76 0.39 5.37e-6 Obesity-related traits; TGCT cis rs7568458 1.000 rs7568458 chr2:85788175 T/A cg17127132 chr2:85788382 GGCX 0.77 7.4 0.55 1.79e-11 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs910316 1.000 rs10143132 chr14:75525850 G/A cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg15782153 chr7:917662 C7orf20 0.5 5.84 0.46 4.24e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs6088590 1.000 rs1998028 chr20:33344595 A/T cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs78487399 0.808 rs79271345 chr2:43746094 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs2469997 1.000 rs2447178 chr8:120356188 C/T cg01792902 chr3:178864926 PIK3CA 0.78 6.66 0.51 7.93e-10 Hypertension (SNP x SNP interaction); TGCT cis rs6693567 0.565 rs10888578 chr1:150260993 A/G cg09579323 chr1:150459698 TARS2 -0.55 -5.2 -0.42 7.92e-7 Migraine; TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg11410718 chr7:27170412 HOXA4 -0.47 -4.68 -0.39 7.38e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6540559 0.546 rs7551944 chr1:210029430 G/C cg23283495 chr1:209979779 IRF6 0.67 5.05 0.41 1.55e-6 Cleft lip with or without cleft palate; TGCT cis rs208520 0.661 rs207099 chr6:66796373 A/C cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs9926296 0.609 rs4785710 chr16:89796756 C/T cg26513180 chr16:89883248 FANCA -0.68 -6.7 -0.52 6.6e-10 Vitiligo; TGCT cis rs838147 0.537 rs485073 chr19:49207255 A/G cg04599840 chr19:48886497 KDELR1 0.23 4.67 0.39 7.81e-6 Dietary macronutrient intake; TGCT cis rs28595532 1.000 rs55634130 chr4:119655093 C/T cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs12497850 1.000 rs6788650 chr3:48749543 T/C cg16497277 chr3:49208875 KLHDC8B -0.5 -4.78 -0.39 4.87e-6 Parkinson's disease; TGCT cis rs875971 1.000 rs1144894 chr7:65542894 A/G cg11764359 chr7:65958608 NA -0.56 -4.7 -0.39 6.74e-6 Aortic root size; TGCT cis rs12950390 0.853 rs11658511 chr17:45856918 T/C cg24803719 chr17:45855879 NA -0.5 -5.12 -0.42 1.15e-6 IgG glycosylation; TGCT cis rs1371867 0.775 rs6511 chr8:101252680 T/C cg06636551 chr8:101224915 SPAG1 0.48 6.46 0.5 2.11e-9 Atrioventricular conduction; TGCT cis rs34779708 0.966 rs12782948 chr10:35450607 G/A cg04310649 chr10:35416472 CREM -0.53 -4.71 -0.39 6.66e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs11718455 1.000 rs1524885 chr3:44031847 G/A cg08738300 chr3:44038990 NA 0.85 6.49 0.5 1.87e-9 Coronary artery disease; TGCT cis rs1971762 0.509 rs784567 chr12:53894465 C/T cg16917193 chr12:54089295 NA -0.96 -9.81 -0.66 3.62e-17 Height; TGCT cis rs7980687 0.662 rs585522 chr12:123550813 A/G cg00376283 chr12:123451042 ABCB9 0.73 5.61 0.45 1.25e-7 Height;Educational attainment;Head circumference (infant); TGCT cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg12310025 chr6:25882481 NA -0.69 -7.5 -0.56 1.08e-11 Blood metabolite levels; TGCT cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs11250098 0.583 rs36030755 chr8:10816771 G/C cg21775007 chr8:11205619 TDH -0.58 -5.47 -0.44 2.43e-7 Morning vs. evening chronotype; TGCT trans rs6762477 0.748 rs11714286 chr3:50185508 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.75 -7.39 -0.55 1.88e-11 Menarche (age at onset); TGCT cis rs8103278 0.507 rs10415988 chr19:46246704 C/T cg11657440 chr19:46296263 DMWD 0.75 7.74 0.57 3.02e-12 Coronary artery disease; TGCT cis rs9853921 0.894 rs9855363 chr3:117954415 T/A cg15509235 chr3:117715573 NA 0.53 4.48 0.37 1.65e-5 JT interval (sulfonylurea treatment interaction); TGCT cis rs3617 0.573 rs9810807 chr3:52924227 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.68 -0.39 7.35e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs112591243 0.685 rs2839282 chr21:47902822 C/G cg10657630 chr21:48055338 PRMT2 -1.06 -5.21 -0.42 7.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs950169 0.887 rs12903946 chr15:84954430 T/C cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs4786125 0.801 rs8057091 chr16:6902148 A/G cg03623568 chr16:6915990 A2BP1 -0.4 -5.61 -0.45 1.26e-7 Heart rate variability traits (SDNN); TGCT cis rs2836974 0.831 rs4375956 chr21:40521788 G/A cg17971929 chr21:40555470 PSMG1 0.98 9.32 0.64 5.67e-16 Cognitive function; TGCT cis rs950169 0.881 rs4081123 chr15:84956235 A/G cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs4906332 1.000 rs12879663 chr14:103874215 A/G cg26031613 chr14:104095156 KLC1 -0.51 -4.62 -0.38 9.61e-6 Coronary artery disease; TGCT cis rs7772486 0.840 rs11155451 chr6:146422524 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.8 0.66 3.86e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs918629 0.679 rs72656689 chr5:95270872 A/G cg16656078 chr5:95278638 ELL2 -0.28 -4.8 -0.4 4.47e-6 IgG glycosylation; TGCT cis rs2153535 0.580 rs6597327 chr6:8482157 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT trans rs28735056 0.967 rs61090726 chr18:77631219 A/G cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT cis rs3784262 0.669 rs4646564 chr15:58351797 G/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6424115 0.830 rs3003335 chr1:24200052 A/G cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs10992471 0.756 rs11792342 chr9:95143668 G/A cg14631576 chr9:95140430 CENPP -0.3 -4.97 -0.41 2.21e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2204008 0.837 rs11612397 chr12:38357455 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs1483890 0.723 rs2007578 chr3:69408982 T/A cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg02493798 chr17:6899577 ALOX12 0.43 4.74 0.39 5.83e-6 Tonsillectomy; TGCT cis rs3806843 0.733 rs801181 chr5:140092814 C/T cg19875535 chr5:140030758 IK -0.35 -5.95 -0.47 2.61e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs16854884 0.586 rs4616638 chr3:143735423 A/T cg06585982 chr3:143692056 C3orf58 -0.57 -4.61 -0.38 9.92e-6 Economic and political preferences (feminism/equality); TGCT cis rs7959452 0.649 rs4761239 chr12:69776886 T/A cg20891283 chr12:69753455 YEATS4 0.86 8.81 0.62 9.49e-15 Blood protein levels; TGCT cis rs7666738 0.830 rs13328042 chr4:99055406 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6831352 0.840 rs34634551 chr4:100067362 C/A cg12011299 chr4:100065546 ADH4 -0.46 -5.22 -0.42 7.38e-7 Alcohol dependence; TGCT cis rs4862750 0.872 rs7664463 chr4:187876686 A/C cg03452623 chr4:187889614 NA -0.34 -5.18 -0.42 8.8e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 0.960 rs12134854 chr1:76137606 A/G cg03433033 chr1:76189801 ACADM 0.83 10.12 0.67 6.52e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs483180 0.512 rs677277 chr1:120202298 C/T cg19096424 chr1:120255104 PHGDH -0.57 -5.19 -0.42 8.35e-7 Macular telangiectasia type 2; TGCT cis rs13191362 1.000 rs34591938 chr6:163087003 C/G cg06582575 chr6:163149167 PACRG;PARK2 0.98 7.63 0.57 5.48e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs4478858 0.735 rs11582342 chr1:31810681 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg10117171 chr1:25599238 RHD 0.3 4.92 0.4 2.69e-6 Erythrocyte sedimentation rate; TGCT cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs13022357 1.000 rs2042495 chr2:160084263 A/G cg00168785 chr2:160142643 WDSUB1 0.46 4.6 0.38 1.04e-5 Sudden cardiac arrest; TGCT cis rs694739 0.628 rs475032 chr11:64140737 G/C cg23796481 chr11:64053134 BAD;GPR137 -0.63 -6.54 -0.51 1.44e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs72945132 0.882 rs56368270 chr11:70162590 A/G cg00319359 chr11:70116639 PPFIA1 0.98 7.13 0.54 7.33e-11 Coronary artery disease; TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg07167872 chr1:205819463 PM20D1 -0.54 -7.05 -0.53 1.1e-10 Menarche (age at onset); TGCT cis rs9796 0.727 rs12101934 chr15:41353079 C/T cg18705301 chr15:41695430 NDUFAF1 -0.49 -6.18 -0.49 8.53e-9 Menopause (age at onset); TGCT cis rs7647973 0.925 rs6446256 chr3:49224210 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.79 -0.4 4.63e-6 Menarche (age at onset); TGCT cis rs2050392 0.858 rs2250569 chr10:30698914 G/C cg18806716 chr10:30721971 MAP3K8 -0.46 -5.37 -0.43 3.74e-7 Inflammatory bowel disease; TGCT cis rs116095464 0.558 rs73029475 chr5:206969 T/C cg22857025 chr5:266934 NA -0.34 -6.71 -0.52 6.3e-10 Breast cancer; TGCT cis rs12540874 0.698 rs3823674 chr7:50571996 C/T cg18232548 chr7:50535776 DDC -0.37 -6.43 -0.5 2.45e-9 Systemic sclerosis; TGCT cis rs986417 0.901 rs1955692 chr14:61008408 C/A cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.38e-15 Gut microbiota (bacterial taxa); TGCT cis rs78487399 0.808 rs6544664 chr2:43729108 T/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.82 -0.4 4.03e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6582630 0.638 rs7963994 chr12:38555535 G/A cg26384229 chr12:38710491 ALG10B -0.52 -4.62 -0.38 9.6e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12908161 0.920 rs12904605 chr15:85201419 T/C cg12863693 chr15:85201151 NMB 0.46 5.54 0.45 1.73e-7 Schizophrenia; TGCT cis rs78487399 0.808 rs13413856 chr2:43764825 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.13 -0.42 1.06e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6011674 0.808 rs56946612 chr20:61849265 T/G cg06763829 chr20:61885236 FLJ16779;NKAIN4 0.85 4.55 0.38 1.28e-5 Response to cytadine analogues (cytosine arabinoside); TGCT cis rs9325144 0.624 rs7979541 chr12:39129679 T/C cg10518543 chr12:38710700 ALG10B -0.48 -4.44 -0.37 1.97e-5 Morning vs. evening chronotype; TGCT cis rs8177179 0.967 rs6439436 chr3:133453779 C/T cg24879335 chr3:133465180 TF -0.36 -5.04 -0.41 1.63e-6 Iron status biomarkers (transferrin levels); TGCT cis rs6121246 0.567 rs6058189 chr20:30192389 A/G cg21427119 chr20:30132790 HM13 -0.38 -5.63 -0.45 1.14e-7 Mean corpuscular hemoglobin; TGCT cis rs7826238 0.594 rs2948285 chr8:8130538 A/T cg06636001 chr8:8085503 FLJ10661 0.73 6.42 0.5 2.56e-9 Systolic blood pressure; TGCT cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs2549003 0.933 rs3846731 chr5:131814264 T/C cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs4822044 0.560 rs7284839 chr22:42010902 C/T cg06481639 chr22:41940642 POLR3H 0.74 6.64 0.51 8.88e-10 Cannabis dependence symptom count; TGCT cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg12034118 chr1:209979487 IRF6 0.67 5.07 0.41 1.43e-6 Cleft lip with or without cleft palate; TGCT cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg17747265 chr1:1875780 NA -0.41 -7.72 -0.57 3.38e-12 Body mass index; TGCT cis rs7772486 0.658 rs4895683 chr6:146113654 T/A cg13319975 chr6:146136371 FBXO30 0.5 4.62 0.38 9.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3806843 0.900 rs2531340 chr5:140131046 C/T cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT trans rs9388451 0.839 rs11154331 chr6:126111429 A/T cg05039488 chr6:79577232 IRAK1BP1 -0.72 -8.03 -0.58 6.54e-13 Brugada syndrome; TGCT cis rs7611238 0.560 rs4461369 chr3:195000811 G/A cg27323046 chr3:195102265 ACAP2 0.35 4.69 0.39 6.99e-6 Body mass index; TGCT cis rs7607369 0.648 rs55983650 chr2:219654932 T/C cg02176678 chr2:219576539 TTLL4 -0.48 -6.11 -0.48 1.17e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs797680 0.856 rs7553465 chr1:93644410 C/T cg17826107 chr1:92977322 EVI5 -0.24 -5.27 -0.43 5.93e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7666738 0.830 rs4699591 chr4:98974171 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 1.000 rs57846982 chr2:99921574 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.79 -5.86 -0.47 3.88e-8 Chronic sinus infection; TGCT cis rs9993613 0.875 rs719381 chr4:73453998 C/T cg15102770 chr4:73434591 ADAMTS3 -0.51 -4.8 -0.4 4.47e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs2594989 0.943 rs9836824 chr3:11463517 G/A cg00170343 chr3:11313890 ATG7 0.72 5.37 0.43 3.8e-7 Circulating chemerin levels; TGCT trans rs17685 0.735 rs11763339 chr7:75761541 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6977660 0.652 rs2072187 chr7:19747915 A/G cg05791153 chr7:19748676 TWISTNB 1.04 6.33 0.49 4.03e-9 Thyroid stimulating hormone; TGCT trans rs7618501 0.699 rs3733135 chr3:49939587 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.87 9.3 0.64 6.15e-16 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs10832963 0.594 rs1550869 chr11:18613498 G/T cg15824435 chr11:18617206 NA 0.34 5.67 0.45 9.61e-8 Breast cancer; TGCT cis rs11577318 0.579 rs11247936 chr1:26698884 A/G cg12733254 chr1:26682999 NA 0.22 4.47 0.37 1.72e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs225245 0.755 rs226432 chr17:34043825 G/A cg05299278 chr17:33885742 SLFN14 -0.21 -4.52 -0.38 1.42e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs1775715 1.000 rs1775715 chr10:32309005 A/G cg14930904 chr10:32216787 ARHGAP12 -0.5 -4.63 -0.38 8.96e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2153535 0.580 rs6921964 chr6:8446395 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.65 0.45 1.02e-7 Motion sickness; TGCT cis rs9611565 0.921 rs2281332 chr22:41746212 T/C cg13695892 chr22:41940480 POLR3H -0.72 -7.37 -0.55 2.15e-11 Vitiligo; TGCT cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs11167764 1.000 rs6580220 chr5:141480558 G/A cg02659431 chr5:141694439 SPRY4 -0.22 -4.72 -0.39 6.31e-6 Crohn's disease; TGCT cis rs7917772 0.582 rs7091252 chr10:104328859 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3617 0.573 rs62253582 chr3:52928333 G/A cg11645453 chr3:52864694 ITIH4 -0.27 -5.14 -0.42 1.05e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9457247 1.000 rs404222 chr6:167402150 G/A cg23791538 chr6:167370224 RNASET2 -0.52 -5.16 -0.42 9.46e-7 Crohn's disease; TGCT cis rs6565180 0.791 rs4247355 chr16:30392099 A/G cg17640201 chr16:30407289 ZNF48 0.96 9.09 0.63 1.94e-15 Tonsillectomy; TGCT cis rs9913156 0.793 rs72835633 chr17:4562643 C/T cg00122941 chr17:4613640 ARRB2 0.87 7.38 0.55 1.95e-11 Lymphocyte counts; TGCT cis rs76473307 1.000 rs6015381 chr20:57393614 G/C cg06163629 chr20:57414884 GNASAS;GNAS -0.67 -4.53 -0.38 1.34e-5 Chronic lymphocytic leukemia; TGCT cis rs2153535 0.580 rs986060 chr6:8465428 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6840360 0.571 rs1822346 chr4:152525303 G/C cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs250677 0.687 rs36048 chr5:148441713 G/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg08736216 chr1:53307985 ZYG11A -0.24 -4.74 -0.39 5.75e-6 Monocyte count; TGCT cis rs3749237 0.595 rs35701831 chr3:49515000 A/C cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs11718455 1.000 rs17076273 chr3:44020113 A/G cg08738300 chr3:44038990 NA 0.88 6.65 0.51 8.52e-10 Coronary artery disease; TGCT cis rs7119038 0.774 rs73005426 chr11:118681083 A/G cg19308663 chr11:118741387 NA 0.27 5.5 0.44 2.11e-7 Sjögren's syndrome; TGCT cis rs10875595 0.836 rs57396973 chr5:140659106 T/A cg24830062 chr5:140700576 TAF7 -0.6 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs1395 0.744 rs11126936 chr2:27483101 A/C cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.61 -7.75 -0.57 2.92e-12 Blood metabolite levels; TGCT cis rs1670533 0.932 rs13137819 chr4:1042115 T/C cg27284194 chr4:1044797 NA 0.67 5.29 0.43 5.34e-7 Recombination rate (females); TGCT cis rs2836974 0.526 rs1888488 chr21:40686521 C/T cg11644478 chr21:40555479 PSMG1 -0.57 -4.9 -0.4 2.9e-6 Cognitive function; TGCT trans rs1496653 0.602 rs13095737 chr3:23524494 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1278769 0.786 rs7998551 chr13:113540649 G/T cg17842918 chr13:113540400 ATP11A -0.32 -4.48 -0.37 1.67e-5 Interstitial lung disease; TGCT cis rs1395 0.767 rs1821986 chr2:27405835 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.5 -6.75 -0.52 5.06e-10 Blood metabolite levels; TGCT cis rs68170813 0.523 rs79619227 chr7:107025335 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs7104764 1.000 rs9795476 chr11:235894 T/G cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs6921919 0.609 rs36018474 chr6:28385529 C/G cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1532993 0.518 rs13142828 chr4:98628307 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs2832191 0.791 rs2832187 chr21:30485543 T/C cg24692254 chr21:30365293 RNF160 -0.94 -10.58 -0.69 4.78e-19 Dental caries; TGCT cis rs1975974 0.511 rs66766425 chr17:21755307 G/T cg18423549 chr17:21743878 NA -0.67 -6.07 -0.48 1.41e-8 Psoriasis; TGCT cis rs4699052 0.928 rs2169511 chr4:104192580 G/A cg16532752 chr4:104119610 CENPE -0.55 -4.97 -0.41 2.19e-6 Testicular germ cell tumor; TGCT cis rs909674 0.541 rs5750812 chr22:39793079 G/A cg01416388 chr22:39784598 NA -0.72 -7.57 -0.56 7.35e-12 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs910316 1.000 rs876402 chr14:75601862 C/T cg08847533 chr14:75593920 NEK9 -0.95 -11.03 -0.7 4.03e-20 Height; TGCT cis rs4689592 0.503 rs2292461 chr4:7058473 C/T cg25660036 chr4:7070649 GRPEL1 -0.62 -5.13 -0.42 1.09e-6 Monocyte percentage of white cells; TGCT cis rs17376456 0.825 rs12716453 chr5:93271697 T/C cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs539096 0.872 rs3791137 chr1:44050004 G/A cg12908607 chr1:44402522 ARTN -0.48 -4.94 -0.41 2.46e-6 Intelligence (multi-trait analysis); TGCT cis rs10832169 0.967 rs1406355 chr11:14067894 C/T cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.55 -5.11 -0.42 1.2e-6 Prudent dietary pattern; TGCT cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg10117171 chr1:25599238 RHD 0.32 5.17 0.42 9.25e-7 Erythrocyte sedimentation rate; TGCT cis rs12519773 0.597 rs17360518 chr5:92457899 A/C cg18783429 chr5:92414398 NA 0.31 4.61 0.38 9.91e-6 Migraine; TGCT cis rs362272 0.525 rs910568 chr4:3307373 A/G cg06533319 chr4:3265114 C4orf44 -0.26 -5.24 -0.43 6.75e-7 Serum sulfate level; TGCT cis rs3020736 0.500 rs6002614 chr22:42501802 G/A cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7216064 0.773 rs11867618 chr17:65875587 G/A cg12091567 chr17:66097778 LOC651250 -0.72 -4.94 -0.41 2.49e-6 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg16145915 chr7:1198662 ZFAND2A -0.43 -5.17 -0.42 9.15e-7 Longevity;Endometriosis; TGCT cis rs6430585 0.583 rs61253125 chr2:136618178 T/C cg07169764 chr2:136633963 MCM6 1.22 12.03 0.73 1.46e-22 Corneal structure; TGCT cis rs3809822 0.617 rs66687178 chr17:7254602 T/G cg02676175 chr17:7253720 KCTD11;ACAP1 -0.53 -5.09 -0.42 1.31e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs36051895 0.632 rs12336875 chr9:5138404 C/A cg02405213 chr9:5042618 JAK2 -0.75 -10.48 -0.69 8.58e-19 Pediatric autoimmune diseases; TGCT cis rs10791097 0.694 rs10160281 chr11:130742788 T/C cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2153535 0.580 rs6902001 chr6:8477055 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7296418 0.630 rs7974099 chr12:123771475 A/G cg00376283 chr12:123451042 ABCB9 0.67 5.81 0.46 4.87e-8 Platelet count; TGCT cis rs1577917 0.958 rs12215265 chr6:86443969 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.17 -0.42 9.02e-7 Response to antipsychotic treatment; TGCT cis rs2486288 0.656 rs12915314 chr15:45551491 C/G cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs6460942 0.915 rs62448602 chr7:12457145 T/G cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs2180341 0.960 rs7773484 chr6:127670779 T/C cg24812749 chr6:127587940 RNF146 1.01 7.62 0.56 5.59e-12 Breast cancer; TGCT cis rs9581857 0.615 rs9581849 chr13:28005782 G/T cg22138327 chr13:27999177 GTF3A 0.81 5.61 0.45 1.26e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6121246 0.520 rs6060425 chr20:30224355 C/T cg18721089 chr20:30220636 NA -0.6 -6.12 -0.48 1.12e-8 Mean corpuscular hemoglobin; TGCT cis rs7698623 0.850 rs1381960 chr4:88801652 A/T cg02735620 chr4:88950514 PKD2 -0.37 -4.44 -0.37 1.98e-5 Cardiovascular disease risk factors; TGCT cis rs3020736 0.500 rs6002601 chr22:42489058 A/T cg05082376 chr22:42548792 NA 0.23 5.38 0.44 3.52e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9814567 1.000 rs6790466 chr3:134197740 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.97 -9.24 -0.64 8.89e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7772486 0.743 rs2092262 chr6:146037105 C/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.75 -0.39 5.58e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9902453 0.933 rs9898353 chr17:28451865 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg05738196 chr6:26577821 NA 0.85 10.41 0.68 1.31e-18 Intelligence (multi-trait analysis); TGCT cis rs2677744 0.688 rs2072078 chr15:91449015 A/G cg23684204 chr15:91497937 RCCD1 0.34 4.89 0.4 3.05e-6 Attention deficit hyperactivity disorder; TGCT cis rs9467603 0.547 rs9295661 chr6:25450026 A/C cg16898833 chr6:26189333 HIST1H4D 1.08 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs7027203 0.688 rs4075733 chr9:96624645 C/T cg14396892 chr9:96623032 NA -0.28 -5.71 -0.46 7.98e-8 DNA methylation (variation); TGCT cis rs669446 0.561 rs568639 chr1:44086080 T/C cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs7668190 0.924 rs4864504 chr4:55097835 G/C cg17187183 chr4:55093834 PDGFRA 0.44 6.04 0.48 1.63e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs4455778 0.561 rs28742972 chr7:48995176 A/G cg26309511 chr7:48887640 NA -0.55 -7.09 -0.54 8.88e-11 Lung cancer in never smokers; TGCT cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.56 0.45 1.58e-7 Height; TGCT trans rs208520 1.000 rs208527 chr6:66957209 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.88 -8.21 -0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs881375 0.967 rs7875829 chr9:123660398 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.08 0.42 1.34e-6 Rheumatoid arthritis; TGCT cis rs2562456 0.874 rs2562417 chr19:21711202 T/C cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs13188771 0.690 rs350561 chr5:100857159 G/A cg10455971 chr5:101119566 NA -0.44 -4.52 -0.38 1.44e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7918232 0.830 rs10764672 chr10:27392541 A/C cg14442939 chr10:27389572 ANKRD26 -0.79 -6.94 -0.53 1.91e-10 Breast cancer; TGCT cis rs2836950 0.501 rs2836984 chr21:40700949 A/C cg11890956 chr21:40555474 PSMG1 -0.64 -5.97 -0.47 2.38e-8 Menarche (age at onset); TGCT cis rs1497406 0.744 rs4537547 chr1:16510798 C/T cg20430773 chr1:16534157 ARHGEF19 -0.56 -6.53 -0.51 1.53e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9486719 1.000 rs2273622 chr6:97058567 A/G cg06623918 chr6:96969491 KIAA0776 -1.02 -8.33 -0.6 1.28e-13 Migraine;Coronary artery disease; TGCT cis rs4808199 0.894 rs10418051 chr19:19397789 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.65 4.89 0.4 3.05e-6 Nonalcoholic fatty liver disease; TGCT cis rs10165862 0.537 rs17009372 chr2:73955571 A/G cg07208825 chr2:73871855 ALMS1P -0.23 -4.96 -0.41 2.24e-6 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg13683864 chr3:40499215 RPL14 -1.19 -13.81 -0.78 7.61e-27 Renal cell carcinoma; TGCT cis rs9522267 0.624 rs1182786 chr13:112196412 A/G cg10483660 chr13:112241077 NA -0.28 -4.45 -0.37 1.92e-5 Hepatitis; TGCT cis rs4660261 0.526 rs810680 chr1:44347856 C/T cg13606994 chr1:44402422 ARTN -0.41 -4.46 -0.37 1.82e-5 Intelligence (multi-trait analysis); TGCT trans rs6740731 0.518 rs35766785 chr2:145295628 C/T cg03855592 chr7:113034122 NA 0.42 6.83 0.52 3.31e-10 Coronary artery disease; TGCT cis rs2295359 1.000 rs4655683 chr1:67611613 C/T cg12940439 chr1:67600707 NA 0.57 5.97 0.47 2.27e-8 Psoriasis; TGCT cis rs9291683 0.655 rs55941493 chr4:10100341 G/A cg00071950 chr4:10020882 SLC2A9 -0.49 -5.12 -0.42 1.13e-6 Bone mineral density; TGCT cis rs6933660 0.760 rs1825368 chr6:151775259 C/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.95 -11.06 -0.7 3.42e-20 Menarche (age at onset); TGCT cis rs7923609 0.967 rs10761752 chr10:65160321 T/C cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.15e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2797160 1.000 rs2211418 chr6:125995503 G/A cg05901451 chr6:126070800 HEY2 -0.73 -6.6 -0.51 1.09e-9 Endometrial cancer; TGCT cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg27535305 chr1:53392650 SCP2 0.26 5.13 0.42 1.09e-6 Monocyte count; TGCT cis rs3015497 0.753 rs12881776 chr14:51136330 T/G cg04730355 chr14:51134070 SAV1 -0.61 -5.86 -0.47 3.95e-8 Mean platelet volume; TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg25767906 chr1:53392781 SCP2 -0.51 -6.22 -0.49 6.83e-9 Monocyte count; TGCT cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg17054783 chr10:134559939 INPP5A 0.24 4.65 0.39 8.27e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12477438 0.798 rs6759354 chr2:99632195 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs10114408 0.959 rs1890378 chr9:96665229 G/A cg13679303 chr9:96623674 NA -0.36 -4.66 -0.39 8e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs73198271 0.583 rs11781985 chr8:8589783 C/T cg06636001 chr8:8085503 FLJ10661 0.68 4.75 0.39 5.42e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9985766 0.958 rs60160057 chr4:151000830 G/A cg05926478 chr4:151174724 DCLK2 -0.24 -4.72 -0.39 6.32e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs9467773 0.873 rs9295698 chr6:26566099 T/A cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs9517313 0.897 rs4772087 chr13:99115041 A/G cg20487152 chr13:99095054 FARP1 0.25 5.1 0.42 1.24e-6 Neuroticism; TGCT cis rs909002 0.849 rs10798879 chr1:32096815 T/C cg11573219 chr1:32083031 HCRTR1 -0.49 -6.44 -0.5 2.36e-9 Intelligence (multi-trait analysis); TGCT cis rs10940138 0.830 rs10447112 chr5:67219761 G/A ch.5.1281357F chr5:67228439 NA 0.44 4.98 0.41 2.05e-6 Menarche (age at onset); TGCT cis rs9372498 0.536 rs62422236 chr6:118972633 G/T cg07617317 chr6:118971624 C6orf204 0.47 4.92 0.4 2.71e-6 Diastolic blood pressure; TGCT cis rs57590327 0.503 rs9852235 chr3:81508355 A/G cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs933688 1.000 rs2367353 chr5:90686568 G/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.05 10.14 0.67 5.91e-18 Smoking behavior; TGCT cis rs7666738 0.830 rs28810677 chr4:99043193 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.554 rs6796411 chr3:10010681 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.31 -4.74 -0.39 5.86e-6 Alzheimer's disease; TGCT cis rs17253792 0.822 rs17683614 chr14:56041058 G/A cg01858014 chr14:56050164 KTN1 -0.36 -4.57 -0.38 1.15e-5 Putamen volume; TGCT trans rs9951602 1.000 rs9951602 chr18:76657779 C/T cg02800362 chr5:177631904 HNRNPAB 0.97 6.69 0.51 6.89e-10 Obesity-related traits; TGCT cis rs4780401 0.588 rs1050068 chr16:11769948 C/T cg01061890 chr16:11836724 TXNDC11 -0.46 -4.52 -0.38 1.45e-5 Rheumatoid arthritis; TGCT cis rs7014346 0.736 rs11985829 chr8:128409232 C/T cg04263511 chr8:128962092 PVT1 0.36 4.7 0.39 6.72e-6 Colorectal cancer; TGCT cis rs7264396 0.635 rs6088971 chr20:34535373 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs6964587 0.967 rs28615927 chr7:91600648 C/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs2180341 0.960 rs7751865 chr6:127683040 G/A cg27446573 chr6:127587934 RNF146 1.14 10.91 0.7 7.51e-20 Breast cancer; TGCT cis rs769267 0.931 rs15622 chr19:19468734 G/A cg03709012 chr19:19516395 GATAD2A -0.69 -5.76 -0.46 6.23e-8 Tonsillectomy; TGCT cis rs2072499 0.554 rs1052067 chr1:156206121 C/T cg24450063 chr1:156163899 SLC25A44 0.7 5.69 0.45 8.83e-8 Testicular germ cell tumor; TGCT cis rs9926296 0.546 rs9935541 chr16:89905925 G/C cg27121462 chr16:89883253 FANCA 0.63 5.93 0.47 2.74e-8 Vitiligo; TGCT cis rs11731606 0.508 rs57403425 chr4:95312411 G/T cg00507259 chr4:95128692 SMARCAD1 0.66 4.85 0.4 3.58e-6 Mean platelet volume; TGCT cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs3617 0.559 rs11915546 chr3:52866845 A/C cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7809950 1.000 rs2520265 chr7:107181231 A/G cg23024343 chr7:107201750 COG5 -0.35 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs950169 0.920 rs12915390 chr15:84792069 T/C cg11189052 chr15:85197271 WDR73 0.73 6.13 0.48 1.06e-8 Schizophrenia; TGCT cis rs4788570 0.697 rs2334877 chr16:71833332 C/T cg06353428 chr16:71660113 MARVELD3 1.52 12.72 0.75 3.08e-24 Intelligence (multi-trait analysis); TGCT cis rs1670533 1.000 rs10007978 chr4:1060984 A/T cg20887711 chr4:1340912 KIAA1530 0.65 5.07 0.41 1.38e-6 Recombination rate (females); TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs7180079 0.514 rs7402386 chr15:65003054 C/T cg03791955 chr15:65024147 NA -0.28 -5.43 -0.44 2.85e-7 Monocyte count; TGCT cis rs5750830 0.546 rs4821891 chr22:39785381 C/T cg24399712 chr22:39784796 NA -1.07 -13.1 -0.76 3.73e-25 Intelligence (multi-trait analysis); TGCT cis rs514406 0.505 rs425520 chr1:53179805 C/G cg24675658 chr1:53192096 ZYG11B -0.79 -9.71 -0.66 6.32e-17 Monocyte count; TGCT cis rs1799949 0.965 rs8070179 chr17:41202688 G/A cg23758822 chr17:41437982 NA 0.68 6.76 0.52 4.84e-10 Menopause (age at onset); TGCT cis rs79387448 0.745 rs72995658 chr2:103176773 A/G cg09003973 chr2:102972529 NA 0.97 6.32 0.49 4.33e-9 Gut microbiota (bacterial taxa); TGCT cis rs9859260 0.701 rs9872347 chr3:195831237 T/C cg02975922 chr3:195473998 MUC4 -0.25 -4.97 -0.41 2.2e-6 Mean corpuscular volume; TGCT cis rs68170813 0.652 rs11532774 chr7:107201579 T/C cg02696742 chr7:106810147 HBP1 -0.59 -4.71 -0.39 6.61e-6 Coronary artery disease; TGCT cis rs5750830 0.649 rs5757663 chr22:39821319 T/C cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs10791323 0.569 rs546381 chr11:133760651 T/G cg03690763 chr11:133734501 NA -0.31 -5.24 -0.43 6.73e-7 Childhood ear infection; TGCT cis rs12549902 0.966 rs12544241 chr8:41514888 G/A cg21772509 chr8:41503840 NKX6-3 0.85 9.62 0.65 1.04e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs4689388 0.890 rs6446481 chr4:6295583 C/A cg25554036 chr4:6271136 WFS1 0.55 7.28 0.55 3.28e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2463822 1.000 rs2513071 chr11:62098387 A/C cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg06481639 chr22:41940642 POLR3H 0.71 6.43 0.5 2.56e-9 Vitiligo; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg22166914 chr1:53195759 ZYG11B 0.3 4.87 0.4 3.29e-6 Monocyte count; TGCT cis rs9486715 0.867 rs1127175 chr6:96999725 C/T cg06623918 chr6:96969491 KIAA0776 -1.1 -13.97 -0.78 3.18e-27 Headache; TGCT cis rs2836974 0.627 rs8127986 chr21:40687211 A/T cg06238570 chr21:40685208 BRWD1 -0.82 -8.52 -0.61 4.53e-14 Cognitive function; TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg04025307 chr7:1156635 C7orf50 0.21 4.95 0.41 2.39e-6 Longevity;Endometriosis; TGCT cis rs1005277 0.505 rs200935 chr10:38132810 T/A cg13531842 chr10:38383804 ZNF37A -0.39 -4.59 -0.38 1.07e-5 Extrinsic epigenetic age acceleration; TGCT cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg17054783 chr10:134559939 INPP5A 0.28 5.64 0.45 1.07e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs28595532 0.920 rs115878132 chr4:119756239 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6920965 0.545 rs614031 chr6:126165720 A/C cg05901451 chr6:126070800 HEY2 -0.56 -5.05 -0.41 1.56e-6 High light scatter reticulocyte count; TGCT cis rs1062177 1.000 rs2915869 chr5:151171509 C/T cg12924095 chr5:151150029 G3BP1 0.35 5.09 0.42 1.31e-6 Preschool internalizing problems; TGCT cis rs477895 0.838 rs2001003 chr11:64018687 C/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 6.93 0.53 2.04e-10 Mean platelet volume; TGCT cis rs1729951 0.575 rs361239 chr3:136701295 G/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs526231 0.578 rs35100629 chr5:102246085 C/G cg23492399 chr5:102201601 PAM -0.51 -4.49 -0.37 1.62e-5 Primary biliary cholangitis; TGCT cis rs7572733 0.534 rs1401092 chr2:198792320 C/A cg00792783 chr2:198669748 PLCL1 -0.57 -5.14 -0.42 1.03e-6 Dermatomyositis; TGCT cis rs56011263 0.687 rs4690187 chr4:703813 C/T cg17689763 chr4:710664 PCGF3 -0.24 -7.23 -0.54 4.25e-11 White blood cell count; TGCT cis rs2594989 0.721 rs9860504 chr3:11573615 G/T cg00170343 chr3:11313890 ATG7 -0.64 -4.77 -0.39 5.18e-6 Circulating chemerin levels; TGCT cis rs8180040 0.701 rs11917474 chr3:47010491 G/A cg27129171 chr3:47204927 SETD2 0.73 9.42 0.65 3.15e-16 Colorectal cancer; TGCT cis rs2180341 0.814 rs7768435 chr6:127737038 A/C cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs12220898 0.749 rs7913006 chr10:50483043 G/T cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT trans rs7618501 0.633 rs9814664 chr3:50078541 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs35160687 0.901 rs10520415 chr2:86498738 C/T cg04877910 chr2:85804641 VAMP8 -0.34 -4.48 -0.37 1.67e-5 Night sleep phenotypes; TGCT cis rs9549260 0.564 rs4943808 chr13:41293950 C/T cg21288729 chr13:41239152 FOXO1 0.94 9.08 0.63 2.07e-15 Red blood cell count; TGCT cis rs9790314 0.503 rs6441374 chr3:161064540 A/T cg03342759 chr3:160939853 NMD3 -0.46 -4.85 -0.4 3.7e-6 Morning vs. evening chronotype; TGCT cis rs9902453 1.000 rs6505158 chr17:28403348 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -6.77 -0.52 4.47e-10 Coffee consumption (cups per day); TGCT cis rs9291683 0.588 rs13121211 chr4:9999539 A/G cg11266682 chr4:10021025 SLC2A9 0.66 8.94 0.63 4.5e-15 Bone mineral density; TGCT cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg22963979 chr7:1858916 MAD1L1 -0.42 -6.58 -0.51 1.19e-9 Bipolar disorder and schizophrenia; TGCT cis rs2243480 1.000 rs2707844 chr7:66059509 G/A cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs12477438 0.798 rs13414153 chr2:99624748 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -5.43 -0.44 2.89e-7 Chronic sinus infection; TGCT cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg16325326 chr1:53192061 ZYG11B -0.84 -11.96 -0.73 2.15e-22 Monocyte count; TGCT trans rs73310256 0.536 rs7078606 chr10:92165861 G/T cg19882243 chr17:80877520 TBCD 0.7 6.65 0.51 8.23e-10 Alzheimer disease and age of onset; TGCT cis rs6448317 0.954 rs35276311 chr4:24923493 C/T cg21108841 chr4:24914750 CCDC149 -0.63 -4.98 -0.41 2.1e-6 Heschl's gyrus morphology; TGCT cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg10802521 chr3:52805072 NEK4 0.72 9.05 0.63 2.45e-15 Bipolar disorder; TGCT cis rs453301 0.624 rs2979265 chr8:8858717 G/C cg06636001 chr8:8085503 FLJ10661 0.8 7.09 0.54 8.97e-11 Joint mobility (Beighton score); TGCT cis rs1568889 0.838 rs10767708 chr11:28294847 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 10.99 0.7 4.8e-20 Bipolar disorder; TGCT cis rs10464366 0.544 rs6952466 chr7:39155032 A/T cg18850127 chr7:39170497 POU6F2 0.33 7.46 0.56 1.34e-11 IgG glycosylation; TGCT cis rs4499344 0.657 rs259238 chr19:33140381 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.8 8.04 0.59 5.95e-13 Mean platelet volume; TGCT cis rs17270561 0.525 rs10484432 chr6:26008876 G/A cg17691542 chr6:26056736 HIST1H1C 1.0 7.07 0.54 9.94e-11 Iron status biomarkers; TGCT cis rs10507380 0.824 rs9512620 chr13:27903333 A/T cg25543773 chr13:27185723 WASF3 0.31 4.49 0.37 1.6e-5 Electrocardiographic traits; TGCT cis rs8180040 0.715 rs6772670 chr3:47191349 G/A cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT cis rs4319547 1.000 rs1392236 chr12:123074890 C/G cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.41 -0.44 3.16e-7 Body mass index; TGCT cis rs2933343 0.700 rs789233 chr3:128603150 G/T cg11901034 chr3:128598214 ACAD9 -0.63 -5.96 -0.47 2.38e-8 IgG glycosylation; TGCT cis rs10193935 0.901 rs13022188 chr2:42704423 A/C cg27598129 chr2:42591480 NA 0.39 5.23 0.43 6.87e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2688608 0.592 rs10762560 chr10:75495405 T/G cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs78456975 0.506 rs10167704 chr2:1571037 G/C cg12573674 chr2:1569213 NA -0.48 -5.21 -0.42 7.78e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs4081724 0.565 rs73026209 chr19:33806610 G/A cg18823272 chr19:34111733 CHST8 0.42 4.7 0.39 6.85e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1215050 0.874 rs17545594 chr4:98652689 A/G cg17366294 chr4:99064904 C4orf37 -0.46 -4.51 -0.38 1.46e-5 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs7819412 0.807 rs4840542 chr8:10944809 G/T cg06636001 chr8:8085503 FLJ10661 -0.8 -7.43 -0.56 1.56e-11 Triglycerides; TGCT cis rs7267979 0.932 rs6138600 chr20:25521346 A/T cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11105298 0.891 rs11105309 chr12:89909850 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs13326165 0.715 rs11705963 chr3:52371991 T/G cg27565382 chr3:53032988 SFMBT1 0.38 5.06 0.41 1.5e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs3733585 0.648 rs28513781 chr4:9959334 G/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs887829 0.569 rs4663333 chr2:234655303 G/T cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.61 -0.38 9.85e-6 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs9611519 0.929 rs13055800 chr22:41440424 G/A cg03806693 chr22:41940476 POLR3H -0.68 -6.1 -0.48 1.25e-8 Neuroticism; TGCT cis rs8082590 1 rs8082590 chr17:17958402 G/A cg09796270 chr17:17721594 SREBF1 -0.26 -5.17 -0.42 9.05e-7 Schizophrenia; TGCT cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.85 -9.07 -0.63 2.22e-15 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg11890956 chr21:40555474 PSMG1 1.11 12.17 0.74 6.69e-23 Cognitive function; TGCT cis rs2243480 0.901 rs778693 chr7:65872345 T/G cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs3780378 0.967 rs12339774 chr9:5045916 C/T cg02405213 chr9:5042618 JAK2 -0.58 -7.5 -0.56 1.09e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs12220238 1.000 rs6480723 chr10:75966366 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs11098499 0.909 rs28668716 chr4:120309875 T/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs28595532 0.841 rs114385163 chr4:119737058 C/T cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs617219 0.671 rs2591392 chr5:78546293 G/A cg05890484 chr5:78407552 BHMT 0.37 5.02 0.41 1.73e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7552404 0.690 rs11161620 chr1:76255228 A/G cg10523679 chr1:76189770 ACADM -0.74 -7.23 -0.54 4.46e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg06238570 chr21:40685208 BRWD1 0.67 6.29 0.49 4.97e-9 Cognitive function; TGCT cis rs2066819 0.792 rs1274496 chr12:56625693 C/A cg26714650 chr12:56694279 CS 1.54 7.77 0.57 2.59e-12 Psoriasis vulgaris; TGCT cis rs12142240 0.667 rs66990604 chr1:46822073 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs28595532 0.920 rs115688334 chr4:119770805 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs2276314 0.600 rs28729782 chr18:33590529 A/G cg19628046 chr18:33552617 C18orf21 0.51 4.6 0.38 1.04e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs11190604 0.607 rs12220970 chr10:102175269 G/A cg16005271 chr10:102321736 NA 0.45 4.48 0.37 1.7e-5 Palmitoleic acid (16:1n-7) levels; TGCT trans rs57221529 0.766 rs17497684 chr5:558307 T/C cg11887960 chr12:57824829 NA 1.15 9.35 0.64 4.71e-16 Lung disease severity in cystic fibrosis; TGCT cis rs6920965 0.507 rs4285341 chr6:126205589 T/G cg05901451 chr6:126070800 HEY2 -0.66 -6.5 -0.5 1.74e-9 High light scatter reticulocyte count; TGCT cis rs8111998 0.826 rs4932776 chr19:22766697 T/C cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs597539 0.690 rs647661 chr11:68625875 T/C cg04772025 chr11:68637568 NA 0.61 6.52 0.51 1.61e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4676380 0.855 rs1583261 chr2:241644740 T/C cg21930842 chr2:241631663 AQP12A 0.3 5.49 0.44 2.13e-7 Response to metformin (IC50); TGCT cis rs7714584 1.000 rs4958422 chr5:150186734 T/G cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs9443189 0.570 rs529383 chr6:76297847 T/G cg01950844 chr6:76311363 SENP6 1.01 6.36 0.5 3.47e-9 Prostate cancer; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg24503407 chr1:205819492 PM20D1 0.6 8.49 0.61 5.35e-14 Menarche (age at onset); TGCT cis rs9372498 0.572 rs56082110 chr6:118909480 A/G cg21191810 chr6:118973309 C6orf204 -0.39 -5.14 -0.42 1.02e-6 Diastolic blood pressure; TGCT cis rs250677 0.687 rs40523 chr5:148444186 A/T cg18129178 chr5:148520854 ABLIM3 0.43 6.17 0.48 9.09e-9 Breast cancer; TGCT cis rs9611519 0.894 rs8136923 chr22:41470522 G/A cg03806693 chr22:41940476 POLR3H -0.66 -5.98 -0.47 2.25e-8 Neuroticism; TGCT cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg22535103 chr8:58192502 C8orf71 -0.46 -5.16 -0.42 9.68e-7 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs6750681 chr2:26329677 C/T cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs889312 0.500 rs832577 chr5:56163787 G/A cg12311346 chr5:56204834 C5orf35 -0.46 -5.0 -0.41 1.87e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs3821902 0.502 rs17718748 chr3:64038816 A/T cg22134162 chr3:63841271 THOC7 0.33 4.54 0.38 1.29e-5 Breast cancer; TGCT cis rs7582180 0.629 rs11685250 chr2:100955137 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs7220711 1.000 rs9897313 chr17:41787558 G/A cg26893861 chr17:41843967 DUSP3 0.52 4.51 0.38 1.47e-5 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs9399135 0.967 rs952674 chr6:135349157 A/G cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs7403037 0.583 rs60600106 chr15:24651180 T/A cg08449389 chr15:24672285 NA 0.43 4.6 0.38 1.04e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs4631830 0.747 rs745180 chr10:51504493 A/C cg10326726 chr10:51549505 MSMB 0.23 4.54 0.38 1.33e-5 Prostate-specific antigen levels; TGCT cis rs12908161 0.960 rs17599989 chr15:85285536 A/G cg17173187 chr15:85201210 NMB 0.56 6.38 0.5 3.18e-9 Schizophrenia; TGCT cis rs60012524 1 rs60012524 chr2:99559117 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.91 -7.46 -0.56 1.34e-11 Chronic sinus infection; TGCT cis rs6867913 0.709 rs2338874 chr5:141466926 G/A cg24830494 chr5:140474986 PCDHB2 -0.4 -4.45 -0.37 1.9e-5 Asthma; TGCT cis rs9682041 0.932 rs7631221 chr3:170069893 A/G cg11886554 chr3:170076028 SKIL 0.83 5.6 0.45 1.3e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs10782582 0.593 rs74968421 chr1:76233496 T/C cg03433033 chr1:76189801 ACADM -0.55 -6.1 -0.48 1.25e-8 Daytime sleep phenotypes; TGCT cis rs137603 0.644 rs137635 chr22:39720656 G/C cg17798944 chr22:39715225 SNORD43;RPL3 -0.68 -7.25 -0.55 3.85e-11 Primary biliary cholangitis; TGCT cis rs8062405 1.000 rs61737565 chr16:28855522 G/C cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs12541335 0.579 rs59283125 chr8:22212311 G/A cg09517075 chr8:22133004 PIWIL2 0.26 5.04 0.41 1.62e-6 Hypertriglyceridemia; TGCT cis rs2050392 0.767 rs10763787 chr10:30700753 G/A cg12408189 chr10:30722286 MAP3K8 0.44 4.46 0.37 1.84e-5 Inflammatory bowel disease; TGCT cis rs4689388 0.856 rs10016157 chr4:6294414 T/C cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3015497 0.616 rs7154131 chr14:51046526 G/C cg04730355 chr14:51134070 SAV1 -0.62 -6.09 -0.48 1.3e-8 Mean platelet volume; TGCT cis rs4665809 1.000 rs6720314 chr2:26334852 G/A cg04944784 chr2:26401820 FAM59B -0.69 -6.5 -0.5 1.8e-9 Gut microbiome composition (summer); TGCT cis rs17030434 0.784 rs4696486 chr4:154651354 T/C cg14289246 chr4:154710475 SFRP2 -0.86 -7.33 -0.55 2.59e-11 Electrocardiographic conduction measures; TGCT cis rs208520 0.690 rs1100981 chr6:66852052 T/C cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT trans rs9990220 0.608 rs1317243 chr3:112053246 C/T cg09134205 chr7:154003215 DPP6 0.36 6.72 0.52 5.93e-10 Eosinophil percentage of white cells; TGCT cis rs1062177 1.000 rs2964585 chr5:151141895 C/T cg12924095 chr5:151150029 G3BP1 0.35 5.04 0.41 1.6e-6 Preschool internalizing problems; TGCT cis rs2836950 0.520 rs2836966 chr21:40637521 A/G cg11890956 chr21:40555474 PSMG1 -0.7 -6.76 -0.52 4.9e-10 Menarche (age at onset); TGCT cis rs1949733 1.000 rs2688223 chr4:8471398 T/C cg11789530 chr4:8429930 ACOX3 0.64 5.99 0.47 2.14e-8 Response to antineoplastic agents; TGCT trans rs7726839 0.561 rs72703050 chr5:582917 A/C cg11887960 chr12:57824829 NA 0.98 7.81 0.57 2.09e-12 Obesity-related traits; TGCT cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg19774624 chr17:42201019 HDAC5 0.88 10.92 0.7 7.5e-20 Total body bone mineral density; TGCT cis rs3733585 0.699 rs17245723 chr4:9962218 A/T cg11266682 chr4:10021025 SLC2A9 -0.57 -7.21 -0.54 4.78e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6860806 0.507 rs272892 chr5:131664349 C/T cg24060327 chr5:131705240 SLC22A5 -0.73 -7.83 -0.58 1.83e-12 Breast cancer; TGCT cis rs6679073 1.000 rs10494874 chr1:205754688 C/G cg23034840 chr1:205782522 SLC41A1 0.7 6.31 0.49 4.59e-9 Prostate-specific antigen levels; TGCT cis rs17345786 0.520 rs12638134 chr3:101334609 G/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.52 5.49 0.44 2.2e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13401104 0.587 rs56146026 chr2:237145629 A/G cg19324714 chr2:237145437 ASB18 0.48 5.03 0.41 1.67e-6 Educational attainment; TGCT cis rs10465746 0.780 rs6703493 chr1:84435812 G/A cg10977910 chr1:84465055 TTLL7 0.69 7.1 0.54 8.56e-11 Obesity-related traits; TGCT trans rs12339966 0.615 rs4333706 chr9:11357040 G/A cg03488587 chr11:64876988 C11orf2 0.3 6.92 0.53 2.12e-10 Systolic blood pressure; TGCT cis rs629922 0.642 rs531831 chr11:114071814 A/G cg01914181 chr11:114070210 ZBTB16 -0.27 -5.14 -0.42 1.05e-6 Paneth cell defects in Crohn's disease; TGCT cis rs2439831 0.850 rs3825783 chr15:44102309 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.27 0.49 5.48e-9 Lung cancer in ever smokers; TGCT cis rs12477438 0.520 rs2516835 chr2:99779131 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs797680 0.820 rs11164879 chr1:93655522 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.89e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6570726 0.791 rs6912079 chr6:145894949 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.58 -0.38 1.13e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7208859 0.673 rs1347359 chr17:28914529 T/C cg14008862 chr17:28927542 LRRC37B2 0.73 4.7 0.39 6.84e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7267979 0.816 rs374701 chr20:25483616 A/G cg16686733 chr20:25566563 NINL 0.52 5.05 0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7954584 0.531 rs6486781 chr12:122318985 A/C cg13699009 chr12:122356056 WDR66 0.3 6.65 0.51 8.41e-10 Mean corpuscular volume; TGCT cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg00475322 chr7:917719 C7orf20 0.52 7.34 0.55 2.4e-11 Perceived unattractiveness to mosquitoes; TGCT cis rs875971 1.000 rs778726 chr7:65828731 C/T cg11764359 chr7:65958608 NA 0.62 5.57 0.45 1.51e-7 Aortic root size; TGCT cis rs1018836 0.564 rs7821994 chr8:91700916 C/T cg16814680 chr8:91681699 NA -1.05 -14.68 -0.8 6.61e-29 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4665809 1.000 rs6720314 chr2:26334852 G/A cg25036284 chr2:26402008 FAM59B -0.53 -4.71 -0.39 6.62e-6 Gut microbiome composition (summer); TGCT cis rs3764563 0.735 rs62106282 chr19:15727124 T/C cg20725493 chr19:15740067 CYP4F8 -0.44 -4.46 -0.37 1.85e-5 Inflammatory biomarkers; TGCT cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg19318889 chr4:1322082 MAEA 0.19 4.53 0.38 1.35e-5 Longevity; TGCT cis rs6089584 1.000 rs3787424 chr20:60559219 G/A cg06108461 chr20:60628389 TAF4 -0.57 -8.01 -0.58 7.25e-13 Body mass index; TGCT cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.700 rs10190421 chr2:99670711 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg11644478 chr21:40555479 PSMG1 1.01 10.47 0.69 8.99e-19 Cognitive function; TGCT cis rs9911578 1.000 rs302859 chr17:56693132 C/T cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs11096990 0.634 rs4975001 chr4:39266464 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.53 -0.38 1.38e-5 Cognitive function; TGCT cis rs3087591 0.922 rs2953013 chr17:29496343 A/C cg24425628 chr17:29625626 OMG;NF1 -0.42 -6.17 -0.48 8.91e-9 Hip circumference; TGCT cis rs2115630 1.000 rs2115630 chr15:85364516 C/T cg12501888 chr15:85177176 SCAND2 -0.49 -4.56 -0.38 1.2e-5 P wave terminal force; TGCT cis rs1801251 0.778 rs709934 chr2:233733352 A/G cg25237894 chr2:233734115 C2orf82 -0.32 -6.23 -0.49 6.73e-9 Coronary artery disease; TGCT cis rs10464366 0.957 rs11765705 chr7:39106942 G/T cg18850127 chr7:39170497 POU6F2 0.21 4.5 0.37 1.55e-5 IgG glycosylation; TGCT cis rs1218582 0.772 rs4845682 chr1:154877105 T/C cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs9486719 0.895 rs4486019 chr6:96883814 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7659604 0.537 rs6823818 chr4:122731699 G/C cg19748678 chr4:122722346 EXOSC9 0.9 9.34 0.64 4.9e-16 Type 2 diabetes; TGCT cis rs7772486 0.875 rs1331640 chr6:146427250 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.5 -0.37 1.56e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs68170813 0.641 rs61511581 chr7:106948091 T/A cg02696742 chr7:106810147 HBP1 -0.72 -6.05 -0.48 1.61e-8 Coronary artery disease; TGCT cis rs1371867 0.846 rs1788180 chr8:101333368 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs911186 0.786 rs13211901 chr6:27187612 G/A cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.55 -4.81 -0.4 4.35e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs17401966 0.838 rs12127604 chr1:10352800 T/G cg19773385 chr1:10388646 KIF1B -0.21 -4.57 -0.38 1.17e-5 Hepatocellular carcinoma; TGCT cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1153858 0.895 rs12593402 chr15:45617392 G/A cg26924012 chr15:45694286 SPATA5L1 1.05 13.95 0.78 3.56e-27 Homoarginine levels; TGCT cis rs72781680 0.752 rs56343114 chr2:23900629 C/G cg08917208 chr2:24149416 ATAD2B 0.84 4.63 0.38 8.91e-6 Lymphocyte counts; TGCT trans rs561341 1.000 rs1681718 chr17:30296445 G/A cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs478304 0.651 rs948494 chr11:65552118 G/A cg10518572 chr11:65560635 OVOL1 -0.24 -4.44 -0.37 1.98e-5 Acne (severe); TGCT cis rs9914988 0.778 rs9907192 chr17:27122426 C/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9341808 0.558 rs2490234 chr6:80816966 G/C cg08355045 chr6:80787529 NA 0.32 5.2 0.42 8.09e-7 Sitting height ratio; TGCT cis rs12136530 0.774 rs10442642 chr1:19773818 A/G cg18923740 chr1:19971790 NBL1 0.37 4.52 0.38 1.44e-5 Lead levels in blood; TGCT cis rs4455778 0.659 rs12718315 chr7:49026733 G/A cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs13408808 0.641 rs10199851 chr2:168583046 T/A cg25427580 chr2:168675357 B3GALT1 0.39 4.52 0.38 1.45e-5 Obesity-related traits; TGCT cis rs2243480 0.522 rs1638736 chr7:66092308 A/T cg18252515 chr7:66147081 NA -0.99 -5.97 -0.47 2.34e-8 Diabetic kidney disease; TGCT cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs7923609 0.811 rs3847325 chr10:65331511 G/C cg08743896 chr10:65200160 JMJD1C 0.32 4.46 0.37 1.82e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs11190604 0.747 rs11190516 chr10:102173525 G/A cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.5e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.830 rs28852677 chr4:99039509 T/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs265548 0.538 rs36688 chr19:17911212 A/C cg16744531 chr19:17905626 B3GNT3 0.42 5.34 0.43 4.26e-7 Tumor biomarkers; TGCT cis rs9807989 0.839 rs10192157 chr2:102968356 C/T cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg01516881 chr6:292596 DUSP22 -0.78 -8.17 -0.59 2.99e-13 Menopause (age at onset); TGCT cis rs7267979 1.000 rs6115146 chr20:25304507 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs912057 0.932 rs1294406 chr6:6737737 A/G cg06612196 chr6:6737390 NA 0.39 4.97 0.41 2.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs6500602 0.727 rs4786509 chr16:4568769 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.32 -5.97 -0.47 2.35e-8 Schizophrenia; TGCT cis rs7103648 0.569 rs11039266 chr11:47532395 T/G cg20307385 chr11:47447363 PSMC3 0.89 8.35 0.6 1.15e-13 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs2013441 1.000 rs2526484 chr17:20103760 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs4242434 0.672 rs900266 chr8:22485295 A/T cg03733263 chr8:22462867 KIAA1967 0.98 13.14 0.76 2.97e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs933688 1.000 rs10059163 chr5:90742444 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.64 0.61 2.4e-14 Smoking behavior; TGCT trans rs854624 0.681 rs12451192 chr17:34337246 C/T cg25044186 chr6:170494475 NA 0.75 6.73 0.52 5.7e-10 Blood protein levels; TGCT cis rs9303401 0.659 rs36093395 chr17:56957357 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT trans rs9388451 0.874 rs13209968 chr6:126089285 G/C cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.38 -0.6 9.81e-14 Brugada syndrome; TGCT cis rs7829975 0.577 rs940030 chr8:8546928 A/G cg06636001 chr8:8085503 FLJ10661 -0.59 -5.09 -0.42 1.3e-6 Mood instability; TGCT cis rs11731606 0.508 rs7696494 chr4:95285174 G/A cg00507259 chr4:95128692 SMARCAD1 0.63 4.72 0.39 6.18e-6 Mean platelet volume; TGCT cis rs11969893 0.850 rs9386260 chr6:101329428 G/A cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs3812831 0.543 rs389108 chr13:114925389 A/G cg15513719 chr13:114904418 NA 0.37 4.56 0.38 1.22e-5 Schizophrenia; TGCT cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.693 rs9915776 chr17:17749056 A/G cg04398451 chr17:18023971 MYO15A 0.31 4.67 0.39 7.57e-6 Total body bone mineral density; TGCT cis rs826838 0.933 rs1906263 chr12:38653362 T/C cg13010199 chr12:38710504 ALG10B 0.77 6.31 0.49 4.59e-9 Heart rate; TGCT cis rs2730245 0.510 rs2788474 chr7:158649005 T/C cg11984989 chr7:158649758 WDR60 1.06 9.85 0.66 2.94e-17 Height; TGCT cis rs7772486 0.790 rs9403755 chr6:146231470 C/A cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4727027 0.835 rs11767810 chr7:148774433 T/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.99 0.41 2.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs734999 0.549 rs2764840 chr1:2529437 C/T cg18854424 chr1:2615690 NA -0.5 -5.9 -0.47 3.25e-8 Ulcerative colitis; TGCT trans rs7698623 0.850 rs1477604 chr4:88771060 C/T cg07071417 chr3:65365250 MAGI1 -0.71 -6.86 -0.52 2.98e-10 Cardiovascular disease risk factors; TGCT cis rs7582180 0.764 rs1530028 chr2:100927910 A/C cg14675211 chr2:100938903 LONRF2 0.52 4.98 0.41 2.1e-6 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.825 rs10058331 chr5:93279115 T/G cg25358565 chr5:93447407 FAM172A 1.03 8.1 0.59 4.5e-13 Diabetic retinopathy; TGCT cis rs9486719 0.802 rs2983896 chr6:97029871 G/A cg18709589 chr6:96969512 KIAA0776 -0.79 -6.36 -0.5 3.44e-9 Migraine;Coronary artery disease; TGCT cis rs7180079 0.502 rs6494466 chr15:64508763 A/G cg13401987 chr15:63569418 APH1B -0.53 -4.62 -0.38 9.39e-6 Monocyte count; TGCT cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg01411255 chr17:61851458 DDX42;CCDC47 -0.73 -7.39 -0.55 1.92e-11 Prudent dietary pattern; TGCT cis rs4689592 0.503 rs11937667 chr4:7057037 C/G cg26116260 chr4:7069785 GRPEL1 -0.85 -6.51 -0.5 1.72e-9 Monocyte percentage of white cells; TGCT cis rs5769765 0.773 rs9616751 chr22:50222236 T/G cg15316289 chr22:50310904 ALG12;CRELD2 0.34 4.77 0.39 5.01e-6 Schizophrenia; TGCT cis rs1577917 0.958 rs13207173 chr6:86457522 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.27 -0.43 5.96e-7 Response to antipsychotic treatment; TGCT cis rs9393777 0.513 rs9368450 chr6:26652489 A/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg03351412 chr1:154909251 PMVK 0.51 4.88 0.4 3.26e-6 Prostate cancer; TGCT cis rs919433 0.679 rs67492914 chr2:198523402 T/G cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs17376456 0.569 rs10050364 chr5:93064127 T/C cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg05368731 chr17:41323189 NBR1 1.19 14.18 0.79 9.89e-28 Menopause (age at onset); TGCT cis rs1008375 0.931 rs6837181 chr4:17701253 A/C cg18681998 chr4:17616180 MED28 0.77 7.29 0.55 3.15e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9467711 0.722 rs13201782 chr6:26651053 T/A cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2153535 0.562 rs10458225 chr6:8386004 G/A cg07606381 chr6:8435919 SLC35B3 -0.54 -5.07 -0.41 1.39e-6 Motion sickness; TGCT trans rs916888 0.647 rs199524 chr17:44848438 G/T cg01341218 chr17:43662625 NA -0.86 -7.5 -0.56 1.06e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.38 -5.63 -0.45 1.15e-7 Alzheimer's disease; TGCT cis rs210138 1.000 rs210138 chr6:33542538 C/T cg07679836 chr6:33548423 BAK1 -0.41 -5.77 -0.46 5.88e-8 Testicular germ cell tumor; TGCT cis rs7213347 0.780 rs1555568 chr17:2149505 T/C cg20777128 chr17:1945076 DPH1;OVCA2 -0.5 -4.46 -0.37 1.84e-5 Total body bone mineral density; TGCT cis rs6840360 0.904 rs6813516 chr4:152594407 C/G cg17479576 chr4:152424074 FAM160A1 -0.56 -6.11 -0.48 1.17e-8 Intelligence (multi-trait analysis); TGCT cis rs13008689 0.875 rs55776708 chr2:8520167 A/C cg21129864 chr2:9369739 ASAP2 -0.2 -4.63 -0.38 8.94e-6 Longevity; TGCT cis rs9322193 0.887 rs9505824 chr6:149954799 A/G cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs8177253 0.965 rs4854762 chr3:133499063 A/G cg01448562 chr3:133502909 NA 0.32 6.58 0.51 1.16e-9 Iron status biomarkers; TGCT cis rs7666738 0.830 rs7667796 chr4:99071415 G/T cg05340658 chr4:99064831 C4orf37 -0.53 -5.88 -0.47 3.62e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.808 rs76851696 chr2:43746062 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs11723283 chr4:99001617 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1362404 0.648 rs7187733 chr16:51993069 C/T cg00216305 chr16:51625890 NA -0.29 -4.71 -0.39 6.6e-6 Gut microbiota (bacterial taxa); TGCT cis rs2237234 0.813 rs34565965 chr6:26350810 T/A cg15659132 chr6:26577336 NA -0.68 -5.21 -0.42 7.75e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs950169 1.000 rs34751999 chr15:84758419 T/C cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.07e-8 Schizophrenia; TGCT cis rs3796352 1.000 rs13078971 chr3:53103645 G/C cg15956490 chr3:53032818 SFMBT1 0.59 6.6 0.51 1.07e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6061231 0.583 rs2427313 chr20:60970675 G/A cg15674680 chr20:60982522 CABLES2 0.72 5.97 0.47 2.29e-8 Colorectal cancer; TGCT cis rs669446 0.561 rs517849 chr1:44081873 A/C cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs3020736 0.500 rs6002618 chr22:42507859 G/C cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1008375 0.900 rs12650220 chr4:17595365 A/T cg18681998 chr4:17616180 MED28 1.0 9.95 0.67 1.69e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6912958 0.703 rs12207825 chr6:88098292 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.62 6.09 0.48 1.29e-8 Monocyte percentage of white cells; TGCT cis rs7940866 0.770 rs10750456 chr11:130819634 A/G cg12179176 chr11:130786555 SNX19 0.62 5.96 0.47 2.43e-8 Schizophrenia; TGCT cis rs6815814 0.898 rs17582830 chr4:38867427 A/G cg02016764 chr4:38805732 TLR1 -0.36 -5.61 -0.45 1.24e-7 Breast cancer; TGCT trans rs1814175 0.619 rs847644 chr11:49918418 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs6918586 0.658 rs198854 chr6:26104057 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.09e-9 Schizophrenia; TGCT trans rs208520 1.000 rs12212063 chr6:66985148 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.8 7.11 0.54 7.9e-11 Exhaled nitric oxide output; TGCT cis rs1008375 1.000 rs13149474 chr4:17688582 G/A cg18681998 chr4:17616180 MED28 -0.91 -8.98 -0.63 3.58e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1005277 0.579 rs2008449 chr10:38414204 A/T cg27523141 chr10:43048294 ZNF37B -0.69 -8.08 -0.59 4.93e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7829975 0.688 rs6601703 chr8:8380224 A/G cg15556689 chr8:8085844 FLJ10661 0.67 6.2 0.49 7.84e-9 Mood instability; TGCT cis rs71636778 0.509 rs35108146 chr1:27248440 C/T cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs554111 0.656 rs10916891 chr1:21199974 A/C cg01072550 chr1:21505969 NA 0.35 5.4 0.44 3.32e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs10114408 0.959 rs7852025 chr9:96647865 G/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs12681287 0.604 rs6471316 chr8:87403587 G/C cg27223183 chr8:87520930 FAM82B 0.87 6.39 0.5 3e-9 Caudate activity during reward; TGCT cis rs8084125 0.832 rs7238522 chr18:74948730 A/C cg05528293 chr18:74961138 GALR1 -0.51 -5.07 -0.41 1.4e-6 Obesity-related traits; TGCT trans rs1814175 0.817 rs10769618 chr11:49822336 A/G cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs1670533 0.685 rs56019586 chr4:1059842 C/G cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs80282103 0.764 rs12244052 chr10:1103266 G/A cg08668510 chr10:1095578 IDI1 1.01 4.51 0.38 1.48e-5 Glomerular filtration rate (creatinine); TGCT cis rs7119 0.689 rs12901765 chr15:77819103 C/A cg27398640 chr15:77910606 LINGO1 -0.26 -4.66 -0.39 7.98e-6 Type 2 diabetes; TGCT cis rs1127311 1.000 rs9427094 chr1:154557685 C/T cg17218026 chr1:154582156 ADAR 0.29 7.29 0.55 3.13e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs1215050 0.740 rs11097580 chr4:98767255 C/A cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs7618501 0.633 rs2526751 chr3:50064867 T/C cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.790 rs1062068 chr6:146207465 A/G cg23711669 chr6:146136114 FBXO30 0.91 10.68 0.69 2.77e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs7192750 0.586 rs6499551 chr16:71943107 T/C cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs259282 0.524 rs3760941 chr19:33130866 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.51 4.69 0.39 7e-6 Schizophrenia; TGCT cis rs2758596 0.850 rs2495270 chr1:156181530 A/G cg25208724 chr1:156163844 SLC25A44 0.99 5.48 0.44 2.3e-7 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs2637266 0.935 rs7900900 chr10:78367383 A/T cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs7833790 0.660 rs67666182 chr8:82772037 A/G cg27398817 chr8:82754497 SNX16 0.69 5.52 0.44 1.9e-7 Diastolic blood pressure; TGCT cis rs561341 0.739 rs4795663 chr17:30214542 T/C cg13647721 chr17:30228624 UTP6 -0.59 -5.21 -0.42 7.66e-7 Hip circumference adjusted for BMI; TGCT cis rs11190604 1.000 rs2495755 chr10:102324649 A/C cg23241863 chr10:102295624 HIF1AN 0.66 4.87 0.4 3.37e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9921338 0.961 rs4781069 chr16:11428762 G/A cg00044050 chr16:11439710 C16orf75 -0.88 -6.75 -0.52 5.08e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs6121246 0.580 rs6121016 chr20:30245239 C/T cg13852791 chr20:30311386 BCL2L1 0.72 4.78 0.39 4.95e-6 Mean corpuscular hemoglobin; TGCT cis rs3780378 0.935 rs2230724 chr9:5081780 G/A cg02405213 chr9:5042618 JAK2 -0.62 -8.3 -0.6 1.48e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9436747 0.641 rs12239395 chr1:66046013 T/C cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.65 0.39 8.37e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs12477438 0.501 rs9941561 chr2:99753829 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs4886920 0.563 rs4886915 chr15:78075023 A/G cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs7772486 0.719 rs702317 chr6:146005010 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs68170813 0.559 rs78064065 chr7:106967440 G/A cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs7267979 1.000 rs2424716 chr20:25423538 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7949030 0.626 rs11231144 chr11:62328038 A/G cg11742103 chr11:62369870 EML3;MTA2 0.62 8.88 0.62 6.35e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11674184 0.659 rs59129126 chr2:11728388 T/C cg07314298 chr2:11723111 GREB1 -0.4 -7.53 -0.56 8.9e-12 Endometriosis; TGCT cis rs11578119 0.866 rs12408130 chr1:170375663 A/G cg09767346 chr1:170501363 GORAB 0.64 4.89 0.4 3.02e-6 Male-pattern baldness; TGCT cis rs644799 0.542 rs10831415 chr11:95466159 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.57 5.72 0.46 7.43e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs916888 0.738 rs199515 chr17:44856641 C/G cg01341218 chr17:43662625 NA -1.09 -8.99 -0.63 3.46e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7769051 1.000 rs9493446 chr6:133125643 C/T cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs62380364 0.774 rs7730255 chr5:88158146 G/C cg22951263 chr5:87985283 NA -0.52 -5.03 -0.41 1.65e-6 Intelligence (multi-trait analysis); TGCT cis rs752010 0.714 rs7552928 chr1:42086664 C/T cg06885757 chr1:42089581 HIVEP3 0.25 4.56 0.38 1.23e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs2067615 0.524 rs1882543 chr12:107067160 A/G cg15890332 chr12:107067104 RFX4 -0.29 -5.71 -0.46 7.83e-8 Heart rate; TGCT cis rs2576037 0.583 rs892586 chr18:44560429 C/A cg23302884 chr18:44338147 ST8SIA5 0.41 4.81 0.4 4.33e-6 Personality dimensions; TGCT cis rs7169223 0.615 rs11630027 chr15:79096983 C/A cg21242079 chr15:79101063 ADAMTS7 0.3 5.02 0.41 1.75e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs427394 0.632 rs2279656 chr5:6737576 G/A cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs17601876 0.814 rs28637352 chr15:51559666 C/A cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT trans rs10506458 1.000 rs1495013 chr12:63428188 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.61 -0.56 5.88e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs3741151 1.000 rs1892856 chr11:73017971 G/C cg17517138 chr11:73019481 ARHGEF17 1.16 5.5 0.44 2.11e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg08859206 chr1:53392774 SCP2 -0.43 -6.47 -0.5 2.07e-9 Monocyte count; TGCT cis rs6500602 0.598 rs3859155 chr16:4593741 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.29 -5.44 -0.44 2.77e-7 Schizophrenia; TGCT trans rs877282 0.945 rs11253396 chr10:789754 C/T cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs1997103 1.000 rs7779040 chr7:55412947 T/C cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7666738 0.546 rs13148080 chr4:98680947 A/G cg05340658 chr4:99064831 C4orf37 0.49 5.29 0.43 5.45e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.560 rs10975009 chr9:5220397 T/G cg02405213 chr9:5042618 JAK2 -0.68 -8.59 -0.61 3.09e-14 Pediatric autoimmune diseases; TGCT cis rs6089829 0.962 rs6122344 chr20:61661738 C/T cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs3793917 0.948 rs11200632 chr10:124211536 A/G cg25576655 chr10:124402963 DMBT1 0.29 4.46 0.37 1.84e-5 Age-related macular degeneration; TGCT cis rs425277 0.628 rs262668 chr1:2082602 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.46 -0.37 1.81e-5 Height; TGCT cis rs838147 0.505 rs1688264 chr19:49209560 T/G cg04599840 chr19:48886497 KDELR1 0.21 4.44 0.37 1.98e-5 Dietary macronutrient intake; TGCT cis rs6988636 0.710 rs62521799 chr8:124134987 G/A cg22384356 chr8:124195192 FAM83A -0.49 -4.72 -0.39 6.35e-6 Urinary uromodulin levels; TGCT cis rs6815814 0.950 rs55903115 chr4:38786474 C/A cg02016764 chr4:38805732 TLR1 -0.36 -5.46 -0.44 2.53e-7 Breast cancer; TGCT cis rs1801251 0.727 rs6437071 chr2:233568793 G/A cg25237894 chr2:233734115 C2orf82 0.25 4.67 0.39 7.56e-6 Coronary artery disease; TGCT cis rs589448 1.000 rs589448 chr12:69752200 A/G cg20891283 chr12:69753455 YEATS4 0.9 10.24 0.68 3.28e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs12477438 0.798 rs4324365 chr2:99623845 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs67311347 0.544 rs60329764 chr3:40334621 C/T cg13683864 chr3:40499215 RPL14 0.8 7.65 0.57 4.79e-12 Renal cell carcinoma; TGCT cis rs9467773 0.935 rs9461270 chr6:26544110 A/G cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs7523273 0.627 rs2724389 chr1:207933648 T/C cg22525895 chr1:207977042 MIR29B2 0.52 8.49 0.61 5.2e-14 Schizophrenia; TGCT cis rs3796352 1.000 rs13072818 chr3:53074263 C/T cg15956490 chr3:53032818 SFMBT1 0.59 6.75 0.52 5.19e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9911578 1.000 rs2333332 chr17:56631054 A/G cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs13118159 0.934 rs4974553 chr4:1356911 G/A cg13395646 chr4:1353034 KIAA1530 -0.37 -4.56 -0.38 1.19e-5 Longevity; TGCT cis rs9467711 0.606 rs13190739 chr6:26587373 G/T cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs9346649 0.616 rs7740995 chr6:168492221 G/A cg02770688 chr6:168491649 NA 0.32 5.58 0.45 1.47e-7 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs9430161 0.611 rs12081181 chr1:11034165 T/G cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs9993613 0.875 rs35100429 chr4:73482344 A/C cg15102770 chr4:73434591 ADAMTS3 0.52 4.89 0.4 3.07e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs4689592 0.503 rs10516184 chr4:7060959 C/T cg25660036 chr4:7070649 GRPEL1 -0.59 -4.6 -0.38 1.01e-5 Monocyte percentage of white cells; TGCT cis rs4788570 0.538 rs16973286 chr16:71552257 C/A cg06353428 chr16:71660113 MARVELD3 -1.32 -7.58 -0.56 6.9e-12 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg26531700 chr6:26746687 NA -0.57 -5.21 -0.42 7.62e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1801251 1.000 rs7578299 chr2:233573469 G/T cg08000102 chr2:233561755 GIGYF2 0.66 6.8 0.52 3.88e-10 Coronary artery disease; TGCT cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT trans rs1814175 0.904 rs7924371 chr11:49620595 C/T cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs3806843 0.612 rs246075 chr5:140300557 T/C cg09824255 chr5:140014002 CD14 0.26 4.58 0.38 1.13e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs2956278 0.717 rs2929744 chr12:84690201 G/A cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2013441 1.000 rs2034109 chr17:20196633 C/T cg18979559 chr17:20280153 CCDC144C -0.49 -5.04 -0.41 1.59e-6 Obesity-related traits; TGCT cis rs933688 0.938 rs10942634 chr5:90658392 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.12 0.67 6.38e-18 Smoking behavior; TGCT trans rs525455 0.966 rs1659844 chr10:13102104 T/G cg21721093 chr17:8906386 NA 0.63 6.62 0.51 9.7e-10 Platelet aggregation; TGCT cis rs9581857 0.685 rs17808758 chr13:28036412 C/T cg22138327 chr13:27999177 GTF3A 0.77 5.24 0.43 6.8e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs968567 0.817 rs61896141 chr11:61556039 A/C cg19610905 chr11:61596333 FADS2 -0.81 -5.14 -0.42 1.04e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs2239547 0.525 rs2246556 chr3:53027983 T/C cg11645453 chr3:52864694 ITIH4 -0.28 -5.27 -0.43 5.73e-7 Schizophrenia; TGCT cis rs259282 0.605 rs3760939 chr19:33106911 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.56 5.12 0.42 1.11e-6 Schizophrenia; TGCT cis rs67366981 0.720 rs4396457 chr14:77685379 G/A cg22824376 chr14:77648248 TMEM63C 0.74 4.75 0.39 5.58e-6 Obsessive-compulsive symptoms; TGCT cis rs7264396 0.635 rs6058351 chr20:34486093 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs854765 0.624 rs9899634 chr17:17727943 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.55 -0.51 1.36e-9 Total body bone mineral density; TGCT cis rs924607 0.898 rs1697990 chr5:626278 A/G cg18765565 chr5:669397 TPPP -0.64 -7.05 -0.54 1.08e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs3087591 0.708 rs7505 chr17:29644852 G/A cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg05025164 chr4:1340916 KIAA1530 -0.57 -5.03 -0.41 1.69e-6 Obesity-related traits; TGCT cis rs2046867 0.862 rs7648954 chr3:72838756 C/A cg25664220 chr3:72788482 NA -0.52 -6.64 -0.51 8.92e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs17221829 0.574 rs2773245 chr11:89372626 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs4325129 1.000 rs12141291 chr1:159460871 C/T cg20944283 chr1:159172620 CADM3 -0.28 -4.44 -0.37 1.96e-5 Obesity-related traits; TGCT cis rs7267979 1.000 rs398036 chr20:25439850 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg03517284 chr6:25882590 NA 0.88 8.68 0.61 1.88e-14 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs7772486 0.622 rs1292333 chr6:145982344 C/T cg05347473 chr6:146136440 FBXO30 -0.48 -4.56 -0.38 1.22e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs910316 0.737 rs175084 chr14:75519175 C/T cg08847533 chr14:75593920 NEK9 -0.85 -8.45 -0.6 6.56e-14 Height; TGCT cis rs2224391 0.628 rs2773316 chr6:5254448 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -0.99 -6.43 -0.5 2.46e-9 Height; TGCT cis rs523522 0.962 rs10849754 chr12:120940418 A/C cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs7833790 0.660 rs10091077 chr8:82705464 A/G cg06027949 chr8:82754900 SNX16 -0.62 -4.74 -0.39 5.73e-6 Diastolic blood pressure; TGCT cis rs12510870 0.674 rs10019320 chr4:74453878 G/A cg05868023 chr4:75230803 EREG -0.55 -4.73 -0.39 5.96e-6 Iris color (b* coordinate); TGCT cis rs9914544 0.545 rs9914914 chr17:18787780 G/A cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs9911578 1.000 rs304270 chr17:56802141 A/G cg12560992 chr17:57184187 TRIM37 -0.77 -9.56 -0.65 1.45e-16 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.559 rs12479491 chr20:30265450 T/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs11785400 0.793 rs2976399 chr8:143746050 C/T cg24634471 chr8:143751801 JRK 0.54 5.29 0.43 5.35e-7 Schizophrenia; TGCT cis rs11172134 0.508 rs1800174 chr12:57559809 G/A cg19258868 chr12:57585184 LRP1 -0.33 -6.06 -0.48 1.48e-8 Urate levels in overweight individuals; TGCT cis rs12579753 0.917 rs12366599 chr12:82212112 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.23 -0.49 6.65e-9 Resting heart rate; TGCT cis rs4805272 0.632 rs7249919 chr19:29335362 C/A cg15000279 chr19:29285009 NA 0.57 6.33 0.49 4.02e-9 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs317689 0.600 rs478863 chr12:69639207 G/A cg11871910 chr12:69753446 YEATS4 0.54 4.47 0.37 1.72e-5 Response to diuretic therapy; TGCT cis rs10089 1.000 rs59484271 chr5:127503781 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.81 7.36 0.55 2.17e-11 Ileal carcinoids; TGCT cis rs3820928 0.904 rs60906902 chr2:227760034 C/T cg11843606 chr2:227700838 RHBDD1 -0.57 -5.13 -0.42 1.08e-6 Pulmonary function; TGCT cis rs6074578 0.679 rs12480529 chr20:137454 T/G cg16931068 chr20:139680 DEFB127 0.27 4.8 0.4 4.52e-6 Hirschsprung disease; TGCT cis rs951366 0.903 rs823116 chr1:205720483 G/A cg07167872 chr1:205819463 PM20D1 0.41 4.77 0.39 4.98e-6 Menarche (age at onset); TGCT cis rs9796 0.689 rs9888710 chr15:41446153 G/C cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.83 -0.52 3.38e-10 Menopause (age at onset); TGCT cis rs12579753 0.956 rs34747993 chr12:82217777 C/T cg07988820 chr12:82153109 PPFIA2 -0.65 -6.81 -0.52 3.72e-10 Resting heart rate; TGCT cis rs28714278 0.644 rs34754163 chr15:40308161 A/C cg21830797 chr15:40226279 EIF2AK4 -0.54 -4.88 -0.4 3.19e-6 Mean corpuscular hemoglobin; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg04317399 chr7:27170313 HOXA4 -0.46 -5.04 -0.41 1.6e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs514406 0.505 rs395169 chr1:53174071 G/A cg24675658 chr1:53192096 ZYG11B -0.78 -9.23 -0.64 9e-16 Monocyte count; TGCT cis rs909002 0.800 rs6703093 chr1:32093561 C/T cg11573219 chr1:32083031 HCRTR1 -0.4 -5.12 -0.42 1.12e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs17345786 0.798 rs1609159 chr3:101275902 A/C cg11279151 chr3:101281821 RG9MTD1 -0.44 -9.82 -0.66 3.38e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.09 -16.1 -0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs9916302 0.904 rs3964723 chr17:37403979 C/T cg07936489 chr17:37558343 FBXL20 -0.63 -5.06 -0.41 1.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs2663905 1.000 rs2663905 chr15:81359137 G/A cg27045999 chr15:81426544 C15orf26 -0.54 -5.49 -0.44 2.12e-7 QT interval (drug interaction); TGCT cis rs75686122 0.892 rs4734077 chr8:104600186 G/A cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs1371867 0.846 rs1613453 chr8:101244215 G/T cg06002616 chr8:101225028 SPAG1 0.53 6.07 0.48 1.45e-8 Atrioventricular conduction; TGCT cis rs832540 0.931 rs832534 chr5:56213672 G/A cg24531977 chr5:56204891 C5orf35 -0.52 -5.18 -0.42 8.65e-7 Coronary artery disease; TGCT cis rs2645424 0.530 rs1293303 chr8:11720227 C/G cg21281001 chr8:11725306 CTSB -0.56 -4.8 -0.4 4.4e-6 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.55 -6.35 -0.5 3.74e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg26818010 chr10:134567672 INPP5A -0.36 -4.95 -0.41 2.33e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2760061 0.626 rs672907 chr1:228120345 G/A cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 15.25 0.81 3.21e-30 Prudent dietary pattern; TGCT cis rs6921919 0.583 rs6928773 chr6:28375210 T/C cg18815343 chr6:28367644 ZSCAN12 -0.53 -5.13 -0.42 1.09e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1005277 0.505 rs719569 chr10:38154415 T/G cg13531842 chr10:38383804 ZNF37A 0.38 4.55 0.38 1.24e-5 Extrinsic epigenetic age acceleration; TGCT cis rs2439831 0.867 rs2927072 chr15:43922398 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.73 4.95 0.41 2.38e-6 Lung cancer in ever smokers; TGCT cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs1395 0.710 rs58965570 chr2:27481460 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.65 8.48 0.61 5.54e-14 Blood metabolite levels; TGCT cis rs2288073 0.965 rs10469924 chr2:24416230 G/A cg05570707 chr2:24270316 C2orf44 -0.5 -4.47 -0.37 1.72e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs2115630 0.936 rs11073663 chr15:85260268 A/G cg11189052 chr15:85197271 WDR73 -0.65 -6.41 -0.5 2.71e-9 P wave terminal force; TGCT cis rs1018836 0.828 rs7816023 chr8:91567398 T/C cg16814680 chr8:91681699 NA -0.75 -7.85 -0.58 1.71e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg22166914 chr1:53195759 ZYG11B 0.34 5.71 0.46 7.92e-8 Monocyte count; TGCT cis rs1476029 0.800 rs105161 chr22:36530428 G/A cg00323501 chr22:37464839 TMPRSS6 -0.53 -4.73 -0.39 6.09e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel + carboplatin); TGCT cis rs10197940 0.624 rs13393122 chr2:152413315 A/G cg06191203 chr2:152266755 RIF1 -0.75 -7.11 -0.54 8.21e-11 Lung cancer; TGCT cis rs739496 0.793 rs76604970 chr12:111967155 A/T cg10833066 chr12:111807467 FAM109A 0.37 5.16 0.42 9.31e-7 Platelet count; TGCT cis rs634534 0.622 rs1192168 chr11:65730945 T/G cg04055107 chr11:65626734 MUS81;CFL1 0.45 4.47 0.37 1.73e-5 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7000551 0.751 rs2469775 chr8:22373238 T/C cg12081754 chr8:22256438 SLC39A14 0.3 4.72 0.39 6.19e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs394563 0.591 rs237035 chr6:149710848 C/T cg16235748 chr6:149772707 ZC3H12D -0.44 -4.9 -0.4 2.87e-6 Dupuytren's disease; TGCT cis rs7666738 0.830 rs9992391 chr4:98916052 G/A cg05340658 chr4:99064831 C4orf37 0.54 6.51 0.5 1.7e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs10823500 0.604 rs10740329 chr10:71941253 A/T cg02100629 chr10:71892760 AIFM2 0.37 4.45 0.37 1.89e-5 Blood protein levels; TGCT cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.61 -0.38 9.75e-6 Obesity-related traits; TGCT cis rs35883536 0.647 rs17402630 chr1:101046587 C/T cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg04013166 chr16:89971882 TCF25 -0.34 -5.16 -0.42 9.42e-7 Skin colour saturation; TGCT cis rs9911578 0.967 rs302842 chr17:56728102 C/G cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs4900538 0.821 rs7012 chr14:102814945 C/T cg18135206 chr14:102964638 TECPR2 -0.19 -4.8 -0.4 4.56e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7119 0.717 rs12904584 chr15:77815991 C/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs6121246 0.909 rs6119729 chr20:30413163 A/G cg13852791 chr20:30311386 BCL2L1 -0.8 -6.12 -0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs10992471 0.603 rs747628 chr9:95289532 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.63 -0.45 1.13e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6051080 1 rs6051080 chr20:25975674 A/G cg03522245 chr20:25566470 NINL 0.52 5.72 0.46 7.43e-8 Colorectal or endometrial cancer; TGCT cis rs12935418 0.583 rs62054240 chr16:81003096 G/C cg07676361 chr16:80966860 NA -0.33 -4.8 -0.4 4.5e-6 Mean corpuscular volume; TGCT cis rs2204008 0.743 rs11182052 chr12:38450421 T/C cg13010199 chr12:38710504 ALG10B 0.57 4.66 0.39 7.88e-6 Bladder cancer; TGCT trans rs4576506 0.536 rs36043162 chr9:31506156 A/C cg11445191 chr5:140227765 PCDHA6;PCDHA2;PCDHA1;PCDHA7;PCDHA5;PCDHA9;PCDHA3;PCDHA4;PCDHA8 0.98 6.69 0.51 6.76e-10 Psychosis and Alzheimer's disease; TGCT cis rs36051895 0.623 rs2208685 chr9:5251758 T/C cg02405213 chr9:5042618 JAK2 -0.7 -8.27 -0.6 1.78e-13 Pediatric autoimmune diseases; TGCT cis rs5167 0.533 rs11083755 chr19:45490065 C/T cg09555818 chr19:45449301 APOC2 0.23 4.62 0.38 9.53e-6 Blood protein levels; TGCT cis rs2580764 0.598 rs2580772 chr2:55218805 G/T cg09592903 chr2:55203963 RTN4 0.25 5.63 0.45 1.12e-7 Mean platelet volume; TGCT cis rs7552404 0.731 rs61770556 chr1:76421902 T/C cg10523679 chr1:76189770 ACADM 0.8 6.76 0.52 4.91e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg03303774 chr4:1407052 NA -0.33 -4.94 -0.41 2.51e-6 Obesity-related traits; TGCT cis rs2730245 0.851 rs2657333 chr7:158728743 G/A cg24397884 chr7:158709396 WDR60 -0.4 -5.3 -0.43 5.05e-7 Height; TGCT cis rs2841277 0.645 rs28380382 chr14:105410827 C/T cg21017887 chr14:105400489 NA 0.35 4.87 0.4 3.38e-6 Rheumatoid arthritis; TGCT cis rs6570726 0.791 rs400329 chr6:145879442 A/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 0.673 rs6698154 chr1:210007777 A/G cg22029157 chr1:209979665 IRF6 0.71 5.09 0.42 1.3e-6 Cleft lip with or without cleft palate; TGCT cis rs12899618 0.688 rs2165489 chr15:71673778 C/T cg16778903 chr15:72612567 BRUNOL6 0.6 4.67 0.39 7.6e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs1153858 1.000 rs10444821 chr15:45647236 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7681440 0.904 rs1822217 chr4:90765052 C/T cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs1577917 0.740 rs9353327 chr6:86394066 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.5 -4.63 -0.38 9.26e-6 Response to antipsychotic treatment; TGCT cis rs1729951 0.575 rs361239 chr3:136701295 G/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs2070488 0.965 rs6802071 chr3:38574237 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.8 -7.82 -0.57 1.91e-12 Electrocardiographic conduction measures; TGCT cis rs9467773 1.000 rs6940188 chr6:26562029 G/C cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.515 rs28853661 chr3:10177659 A/G cg00149659 chr3:10157352 C3orf10 0.98 6.97 0.53 1.68e-10 Alzheimer's disease; TGCT cis rs10791097 0.694 rs4457753 chr11:130755575 A/G cg14779329 chr11:130786720 SNX19 0.29 5.0 0.41 1.9e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4409675 0.576 rs7536088 chr1:28234325 A/G cg23691781 chr1:28212827 C1orf38 0.25 5.12 0.42 1.11e-6 Corneal astigmatism; TGCT cis rs11785400 0.793 rs4457308 chr8:143733922 G/A cg24634471 chr8:143751801 JRK 0.55 5.53 0.44 1.85e-7 Schizophrenia; TGCT cis rs7264396 0.690 rs2425164 chr20:34434916 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.83 -0.4 3.89e-6 Total cholesterol levels; TGCT cis rs59107033 0.607 rs17295401 chr3:123128413 C/T cg04890266 chr3:123102914 ADCY5 0.37 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs763121 0.853 rs8142098 chr22:39058757 T/G cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.9e-12 Menopause (age at onset); TGCT cis rs35306767 0.761 rs12359796 chr10:1021479 G/C cg20503657 chr10:835505 NA 0.58 6.48 0.5 1.92e-9 Eosinophil percentage of granulocytes; TGCT cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg00343986 chr7:65444356 GUSB 0.26 6.14 0.48 1.02e-8 Aortic root size; TGCT cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg27286337 chr10:134555280 INPP5A 0.43 5.41 0.44 3.06e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4253772 0.591 rs7291444 chr22:46656246 T/G cg09491104 chr22:46646882 C22orf40 -0.66 -6.63 -0.51 9.44e-10 LDL cholesterol;Cholesterol, total; TGCT cis rs7552404 1.000 rs9662166 chr1:76235906 C/A cg22875332 chr1:76189707 ACADM 0.76 8.83 0.62 8.53e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7267979 0.866 rs6138609 chr20:25570985 T/A cg03522245 chr20:25566470 NINL 0.6 6.43 0.5 2.48e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2354432 0.556 rs7520661 chr1:146793149 A/G cg25205988 chr1:146714368 CHD1L -1.36 -6.36 -0.5 3.58e-9 Mitochondrial DNA levels; TGCT cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs2070433 0.539 rs721131 chr21:47957767 T/C cg12379764 chr21:47803548 PCNT 0.53 5.38 0.43 3.6e-7 Lymphocyte counts; TGCT cis rs5769765 0.955 rs1321 chr22:50297435 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs155076 1.000 rs195570 chr13:21867580 T/G cg11317459 chr13:21872234 NA -1.3 -11.64 -0.72 1.26e-21 White matter hyperintensity burden; TGCT cis rs4566357 1.000 rs12612535 chr2:227926998 T/C cg11843606 chr2:227700838 RHBDD1 -0.5 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg07061783 chr6:25882402 NA -0.57 -5.44 -0.44 2.74e-7 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.614 rs9973737 chr2:100942296 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.615 rs35288118 chr17:56600748 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs950776 0.593 rs6495306 chr15:78865893 C/T cg06917634 chr15:78832804 PSMA4 -0.65 -5.35 -0.43 4.11e-7 Sudden cardiac arrest; TGCT cis rs6901250 0.655 rs9384990 chr6:117126941 A/G cg12892004 chr6:117198278 RFX6 0.45 5.65 0.45 1.05e-7 C-reactive protein levels; TGCT cis rs9928842 0.882 rs3169330 chr16:75269267 A/G cg09066997 chr16:75300724 BCAR1 0.28 5.09 0.42 1.29e-6 Alcoholic chronic pancreatitis; TGCT trans rs7613875 0.543 rs34034116 chr3:49959156 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.21 0.59 2.46e-13 Body mass index; TGCT cis rs10791097 0.739 rs12279359 chr11:130730544 G/A cg14779329 chr11:130786720 SNX19 0.25 4.44 0.37 1.96e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6540559 0.546 rs59435160 chr1:210030730 C/A cg21951975 chr1:209979733 IRF6 0.76 5.87 0.47 3.66e-8 Cleft lip with or without cleft palate; TGCT cis rs9993613 1.000 rs28627296 chr4:73487092 G/A cg15102770 chr4:73434591 ADAMTS3 -0.52 -4.89 -0.4 3.1e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs16939607 0.818 rs56080040 chr8:79009063 T/C cg21244580 chr8:79934476 NA 0.47 4.68 0.39 7.33e-6 White blood cell count; TGCT cis rs17376456 0.569 rs7701114 chr5:93096028 T/C cg21475434 chr5:93447410 FAM172A 0.6 4.9 0.4 2.92e-6 Diabetic retinopathy; TGCT trans rs9650657 0.504 rs10109167 chr8:11033525 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.81 -0.52 3.65e-10 Neuroticism; TGCT cis rs9467711 0.790 rs34158769 chr6:26336572 G/A cg05948654 chr6:25930507 SLC17A2 0.34 4.54 0.38 1.29e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6921919 0.583 rs1416918 chr6:28358335 G/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.32 -0.43 4.76e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2637266 1.000 rs11001835 chr10:78364770 A/G cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs4072980 0.524 rs28477803 chr1:38398694 C/T cg26398791 chr1:38455867 SF3A3 -0.57 -4.55 -0.38 1.27e-5 Coronary artery disease; TGCT cis rs11190604 1.000 rs7071271 chr10:102264824 G/A cg16342193 chr10:102329863 NA -0.38 -4.89 -0.4 3.06e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9921338 0.961 rs72773832 chr16:11413123 G/A cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs704 0.585 rs1007398 chr17:26665648 A/G cg10342447 chr17:26645325 TMEM97 -0.61 -6.14 -0.48 1.02e-8 Osteoprotegerin levels; TGCT cis rs9952991 0.883 rs2847293 chr18:12782448 A/T cg09945482 chr18:12777974 NA 0.5 4.75 0.39 5.61e-6 Inflammatory skin disease; TGCT cis rs7572733 0.534 rs700687 chr2:198721560 A/T cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs1030877 0.889 rs2576746 chr2:105909559 G/A cg02079111 chr2:105885981 TGFBRAP1 0.2 5.94 0.47 2.71e-8 Obesity-related traits; TGCT cis rs9457247 1.000 rs422780 chr6:167406209 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs17102423 0.740 rs35520739 chr14:65577612 T/C cg11161011 chr14:65562177 MAX 0.44 5.82 0.46 4.63e-8 Obesity-related traits; TGCT cis rs17221829 0.965 rs12292340 chr11:89461273 C/A cg02982614 chr11:89391479 FOLH1B -0.3 -5.15 -0.42 9.89e-7 Anxiety in major depressive disorder; TGCT cis rs12478296 1.000 rs55717005 chr2:243041071 T/A cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs12438659 1 rs12438659 chr15:78824924 G/A cg24631222 chr15:78858424 CHRNA5 0.93 7.96 0.58 9.55e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT trans rs208520 0.690 rs851464 chr6:66839802 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg13695892 chr22:41940480 POLR3H -0.87 -8.24 -0.59 2.06e-13 Vitiligo; TGCT cis rs896854 0.530 rs10956934 chr8:95992473 C/A cg09323728 chr8:95962352 TP53INP1 -0.44 -5.07 -0.41 1.44e-6 Type 2 diabetes; TGCT cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg06481639 chr22:41940642 POLR3H 0.71 6.43 0.5 2.56e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs208520 0.674 rs207103 chr6:66795568 G/T cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs875971 0.619 rs10278371 chr7:66051540 C/A cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs3771570 1.000 rs1984598 chr2:242284824 G/A cg21155796 chr2:242212141 HDLBP 0.85 6.44 0.5 2.41e-9 Prostate cancer; TGCT cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg12310025 chr6:25882481 NA -0.66 -6.01 -0.48 1.88e-8 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs9380047 chr6:28037893 G/T cg12963246 chr6:28129442 ZNF389 0.51 4.97 0.41 2.19e-6 Depression; TGCT cis rs68170813 0.559 rs12536491 chr7:106978024 T/G cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs1691799 0.867 rs1168344 chr12:66758213 G/A cg16791601 chr12:66731901 HELB -0.29 -6.18 -0.49 8.39e-9 White blood cell count (basophil); TGCT cis rs7568458 0.846 rs6547621 chr2:85774676 G/A cg17127132 chr2:85788382 GGCX 0.68 6.59 0.51 1.12e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7714584 1.000 rs931058 chr5:150333698 A/T cg22134413 chr5:150180641 NA 1.01 5.68 0.45 9.02e-8 Crohn's disease; TGCT cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg13342137 chr4:2252803 MXD4 0.17 4.51 0.38 1.5e-5 Obesity-related traits; TGCT cis rs8072100 0.790 rs6505048 chr17:45674998 G/A cg08085267 chr17:45401833 C17orf57 0.46 5.01 0.41 1.82e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6570726 0.764 rs9403731 chr6:145907937 G/A cg23711669 chr6:146136114 FBXO30 0.85 8.98 0.63 3.55e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs11858159 0.565 rs8038318 chr15:24807060 T/C cg08449389 chr15:24672285 NA 0.44 4.67 0.39 7.76e-6 Platelet thrombus formation; TGCT cis rs10782582 0.609 rs5745545 chr1:76377356 A/G cg10523679 chr1:76189770 ACADM -0.58 -5.18 -0.42 8.57e-7 Daytime sleep phenotypes; TGCT cis rs514406 0.861 rs35517489 chr1:53304062 G/C cg08736216 chr1:53307985 ZYG11A -0.27 -5.27 -0.43 5.79e-7 Monocyte count; TGCT trans rs2727020 0.734 rs1164663 chr11:49294723 A/T cg03929089 chr4:120376271 NA 0.67 6.89 0.53 2.44e-10 Coronary artery disease; TGCT cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg21016266 chr12:122356598 WDR66 0.51 7.28 0.55 3.42e-11 Mean corpuscular volume; TGCT cis rs7714584 1.000 rs11957134 chr5:150230950 A/G cg22134413 chr5:150180641 NA -1.11 -8.06 -0.59 5.42e-13 Crohn's disease; TGCT cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9303401 1.000 rs7218362 chr17:56888299 A/G cg12560992 chr17:57184187 TRIM37 0.54 5.61 0.45 1.26e-7 Cognitive test performance; TGCT cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg17554472 chr22:41940697 POLR3H -0.49 -5.26 -0.43 6.14e-7 Vitiligo; TGCT cis rs3008870 1.000 rs3008848 chr1:67379284 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.08 0.74 1.11e-22 Lymphocyte percentage of white cells; TGCT cis rs8031584 0.678 rs4779497 chr15:31151365 T/A cg08109568 chr15:31115862 NA -0.38 -5.03 -0.41 1.67e-6 Huntington's disease progression; TGCT cis rs2224391 0.628 rs11752747 chr6:5272671 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -1.06 -6.44 -0.5 2.44e-9 Height; TGCT cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs6430585 0.583 rs79633114 chr2:136586825 C/T cg07169764 chr2:136633963 MCM6 1.22 11.81 0.73 4.95e-22 Corneal structure; TGCT cis rs4927850 1.000 rs4927850 chr3:195751630 C/T cg02975922 chr3:195473998 MUC4 0.24 5.51 0.44 2.02e-7 Pancreatic cancer; TGCT cis rs4699052 0.625 rs1400365 chr4:104289396 C/G cg16532752 chr4:104119610 CENPE -0.51 -4.86 -0.4 3.49e-6 Testicular germ cell tumor; TGCT cis rs651907 0.514 rs55654108 chr3:101425703 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.54 5.0 0.41 1.91e-6 Colorectal cancer; TGCT cis rs9314614 1.000 rs2978894 chr8:6693629 G/C cg27319216 chr8:6693540 XKR5 -0.29 -4.92 -0.4 2.66e-6 IgA nephropathy;White blood cell count (basophil); TGCT cis rs6912958 0.547 rs451089 chr6:88041859 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.73 7.63 0.57 5.25e-12 Monocyte percentage of white cells; TGCT cis rs6089829 0.889 rs6062773 chr20:61663262 G/C cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs610932 0.517 rs666555 chr11:59970984 G/A cg18570331 chr11:60101691 MS4A6E 0.52 4.73 0.39 6.07e-6 Alzheimer's disease; TGCT cis rs9372498 0.908 rs72967573 chr6:118696532 C/T cg21191810 chr6:118973309 C6orf204 -0.5 -4.61 -0.38 9.92e-6 Diastolic blood pressure; TGCT cis rs782590 0.694 rs2627775 chr2:55877113 C/T cg18811423 chr2:55921094 PNPT1 0.54 5.51 0.44 1.97e-7 Metabolic syndrome; TGCT cis rs4455778 0.536 rs38769 chr7:48940934 C/T cg26309511 chr7:48887640 NA 0.46 5.48 0.44 2.28e-7 Lung cancer in never smokers; TGCT cis rs853679 0.517 rs34716816 chr6:28046169 C/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg07424592 chr7:64974309 NA 1.22 7.36 0.55 2.2e-11 Diabetic kidney disease; TGCT cis rs6500602 0.702 rs11076834 chr16:4549583 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.95 0.47 2.54e-8 Schizophrenia; TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.33 0.43 4.5e-7 Prudent dietary pattern; TGCT cis rs17376456 0.597 rs6869110 chr5:93355531 G/A cg21475434 chr5:93447410 FAM172A -0.62 -5.93 -0.47 2.77e-8 Diabetic retinopathy; TGCT cis rs2692947 0.673 rs4907299 chr2:96780122 G/T cg22654517 chr2:96458247 NA 0.24 5.08 0.41 1.36e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs986417 0.818 rs965455 chr14:60960314 A/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs7302981 0.967 rs7297421 chr12:50518926 C/T cg23855989 chr12:50355821 AQP5 -0.3 -4.44 -0.37 2e-5 Systolic blood pressure; TGCT cis rs7809950 1.000 rs7793613 chr7:107250484 C/T cg23024343 chr7:107201750 COG5 -0.33 -5.21 -0.42 7.63e-7 Coronary artery disease; TGCT cis rs6977660 0.598 rs72591445 chr7:19773035 G/A cg05791153 chr7:19748676 TWISTNB 1.17 7.73 0.57 3.22e-12 Thyroid stimulating hormone; TGCT cis rs7267979 1.000 rs4813566 chr20:25386465 G/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs763121 0.853 rs5757203 chr22:39044152 G/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT trans rs561341 0.769 rs559228 chr17:30294527 T/C cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs78487399 0.808 rs111783562 chr2:43759381 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -4.75 -0.39 5.47e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs637571 0.544 rs617791 chr11:65702523 C/G cg04055107 chr11:65626734 MUS81;CFL1 0.51 5.14 0.42 1.03e-6 Eosinophil percentage of white cells; TGCT cis rs7698623 0.850 rs7684659 chr4:88769571 G/A cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs155076 0.938 rs9509633 chr13:21844482 G/C cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs1372520 0.564 rs356186 chr4:90705364 A/G cg15133208 chr4:90757351 SNCA -0.49 -5.68 -0.45 9.08e-8 Neuroticism; TGCT cis rs8180040 0.966 rs59586735 chr3:47518325 C/T cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs10982256 0.567 rs11791072 chr9:117238655 C/T cg13965272 chr9:117993982 DEC1 -0.23 -4.62 -0.38 9.5e-6 Bipolar disorder; TGCT cis rs9419702 0.568 rs7920966 chr10:133555185 G/T cg20568497 chr10:133558893 NA 0.43 4.85 0.4 3.56e-6 Survival in rectal cancer; TGCT cis rs10871290 0.881 rs3863436 chr16:74468038 T/C cg01733217 chr16:74700730 RFWD3 -0.61 -5.8 -0.46 5.1e-8 Breast cancer; TGCT cis rs1691799 0.867 rs1168316 chr12:66746239 A/G cg16791601 chr12:66731901 HELB -0.28 -6.18 -0.49 8.52e-9 White blood cell count (basophil); TGCT cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg03517284 chr6:25882590 NA -0.53 -5.43 -0.44 2.88e-7 Blood metabolite levels; TGCT cis rs6912958 0.781 rs4707376 chr6:88270947 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs2840044 1.000 rs17637907 chr17:33891386 A/G cg05299278 chr17:33885742 SLFN14 -0.24 -5.58 -0.45 1.43e-7 Response to radiotherapy in cancer (late toxicity); TGCT cis rs8177253 1.000 rs8177252 chr3:133480174 C/A cg16414030 chr3:133502952 NA -0.61 -9.65 -0.66 8.74e-17 Iron status biomarkers; TGCT cis rs7809950 0.678 rs2237665 chr7:106906998 T/C cg23024343 chr7:107201750 COG5 -0.43 -5.81 -0.46 4.86e-8 Coronary artery disease; TGCT cis rs9549367 0.789 rs3764125 chr13:113897648 A/G cg00898013 chr13:113819073 PROZ 0.37 4.65 0.39 8.35e-6 Platelet distribution width; TGCT cis rs9911578 1.000 rs9898626 chr17:56698219 C/G cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs6674176 0.932 rs4660761 chr1:44440146 G/A cg12908607 chr1:44402522 ARTN -0.74 -8.47 -0.61 5.88e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6089829 0.962 rs11086151 chr20:61664644 C/T cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs709400 0.659 rs3825566 chr14:103852725 C/T cg26031613 chr14:104095156 KLC1 -0.84 -9.12 -0.63 1.71e-15 Body mass index; TGCT cis rs8031584 0.678 rs35098644 chr15:31145440 A/G cg08704250 chr15:31115839 NA -0.42 -5.82 -0.46 4.74e-8 Huntington's disease progression; TGCT cis rs7659604 0.502 rs13104233 chr4:122672473 T/C cg19748678 chr4:122722346 EXOSC9 -0.51 -5.01 -0.41 1.84e-6 Type 2 diabetes; TGCT trans rs208520 0.690 rs12197578 chr6:66725905 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs7412746 0.658 rs12068264 chr1:150727329 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.57 0.38 1.15e-5 Melanoma; TGCT cis rs200810 0.694 rs71562340 chr6:98031290 G/A cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.65 -4.44 -0.37 1.94e-5 Body mass index; TGCT cis rs1997103 1.000 rs6973337 chr7:55411534 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs8072100 0.640 rs3851808 chr17:45425144 C/T cg08085267 chr17:45401833 C17orf57 -0.46 -5.03 -0.41 1.68e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs60843830 0.964 rs17713568 chr2:242132 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.75 7.63 0.57 5.51e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9467711 0.606 rs9393715 chr6:26375645 G/A cg10795676 chr6:26370623 BTN3A2 -0.47 -4.77 -0.39 5e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs476633 0.708 rs28629856 chr15:41446950 C/T cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.77 -0.62 1.18e-14 Glomerular filtration rate (creatinine); TGCT cis rs3812831 0.643 rs7322339 chr13:114929726 C/A cg15513719 chr13:114904418 NA 0.39 4.73 0.39 6.05e-6 Schizophrenia; TGCT cis rs7923609 0.783 rs4746203 chr10:65323997 G/T cg08743896 chr10:65200160 JMJD1C 0.32 4.47 0.37 1.73e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2735413 0.564 rs7192226 chr16:78120260 T/A cg09132178 chr16:78079569 NA 0.35 4.51 0.38 1.47e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs35306767 0.715 rs1871622 chr10:1049309 T/G cg26597838 chr10:835615 NA 0.6 6.63 0.51 9.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs11190604 0.945 rs2495735 chr10:102338609 G/A cg23241863 chr10:102295624 HIF1AN 0.71 5.39 0.44 3.39e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs629535 0.911 rs490165 chr8:70014976 A/G cg21567404 chr3:27674614 NA -0.58 -9.46 -0.65 2.51e-16 Dupuytren's disease; TGCT cis rs950169 0.763 rs35372971 chr15:84941795 G/A cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg04013166 chr16:89971882 TCF25 0.32 4.61 0.38 9.93e-6 Skin colour saturation; TGCT cis rs526231 0.819 rs411648 chr5:102602902 A/T cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs66561647 0.634 rs10097497 chr8:128932363 A/G cg05480350 chr8:128972681 MIR1205;PVT1 0.21 4.45 0.37 1.88e-5 Hemoglobin concentration; TGCT cis rs7017914 0.905 rs2639956 chr8:71924091 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.2e-6 Bone mineral density; TGCT cis rs9517320 0.534 rs9556962 chr13:99156648 C/T cg07423050 chr13:99094983 FARP1 -0.29 -5.81 -0.46 5.02e-8 Longevity; TGCT cis rs6089584 0.888 rs6061981 chr20:60618973 T/C cg16423285 chr20:60520624 NA -0.61 -6.57 -0.51 1.23e-9 Body mass index; TGCT cis rs9303401 0.580 rs34076823 chr17:57114497 C/G cg02118635 chr17:56770003 RAD51C;TEX14 0.56 5.59 0.45 1.4e-7 Cognitive test performance; TGCT cis rs11578119 0.933 rs7512094 chr1:170408985 A/C cg09767346 chr1:170501363 GORAB 0.71 5.66 0.45 9.92e-8 Male-pattern baldness; TGCT cis rs10791097 0.694 rs2155752 chr11:130755998 C/T cg12179176 chr11:130786555 SNX19 0.83 9.92 0.67 1.94e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7412746 0.571 rs12402939 chr1:150615094 A/C cg04414720 chr1:150670196 GOLPH3L 0.4 4.97 0.41 2.19e-6 Melanoma; TGCT cis rs986417 1.000 rs1254292 chr14:60863636 T/C cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs9814567 1.000 rs35718987 chr3:134272783 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs950169 0.656 rs748455 chr15:85149575 T/C cg11189052 chr15:85197271 WDR73 0.78 6.71 0.52 6.11e-10 Schizophrenia; TGCT cis rs7824557 0.614 rs5029571 chr8:11213389 C/T cg21775007 chr8:11205619 TDH 0.68 6.46 0.5 2.16e-9 Retinal vascular caliber; TGCT cis rs9486719 0.552 rs9399923 chr6:96850379 G/A cg06623918 chr6:96969491 KIAA0776 0.87 7.0 0.53 1.41e-10 Migraine;Coronary artery disease; TGCT cis rs6964587 0.967 rs12671991 chr7:91559481 T/C cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs933688 0.938 rs7705465 chr5:90680949 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.05 0.59 5.84e-13 Smoking behavior; TGCT cis rs1050631 1.000 rs11081934 chr18:33705304 G/A cg25426722 chr18:33708991 SLC39A6;ELP2 0.49 4.84 0.4 3.76e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs6121246 0.529 rs6058196 chr20:30194714 A/T cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs6565180 0.888 rs8060853 chr16:30403858 A/G cg17640201 chr16:30407289 ZNF48 0.94 8.64 0.61 2.29e-14 Tonsillectomy; TGCT cis rs7394190 0.748 rs2306325 chr10:75506674 T/C cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.48e-6 Incident atrial fibrillation; TGCT cis rs9522267 0.535 rs7326875 chr13:112236231 C/T cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs2274273 0.712 rs17832311 chr14:55534466 A/G cg01923255 chr14:55878535 KIAA0831 0.57 4.89 0.4 3.03e-6 Protein biomarker; TGCT cis rs7584330 0.822 rs13390494 chr2:238388792 G/A cg14458575 chr2:238380390 NA 0.48 7.42 0.55 1.66e-11 Prostate cancer; TGCT cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg06238570 chr21:40685208 BRWD1 0.73 6.66 0.51 8.12e-10 Cognitive function; TGCT cis rs4595586 0.870 rs1400285 chr12:39277867 T/C cg10518543 chr12:38710700 ALG10B -0.47 -4.67 -0.39 7.64e-6 Morning vs. evening chronotype; TGCT cis rs28595532 0.920 rs114165587 chr4:119779525 C/T cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs1153858 1.000 rs7402650 chr15:45701895 C/T cg26924012 chr15:45694286 SPATA5L1 1.1 15.34 0.81 2.01e-30 Homoarginine levels; TGCT cis rs6912958 0.781 rs2268993 chr6:88184111 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs7772486 0.875 rs2748497 chr6:146319417 C/T cg05347473 chr6:146136440 FBXO30 0.49 4.47 0.37 1.74e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2239547 0.522 rs6771610 chr3:53026104 T/C cg11645453 chr3:52864694 ITIH4 0.33 5.28 0.43 5.48e-7 Schizophrenia; TGCT cis rs11122272 0.735 rs2572252 chr1:231513653 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs9611565 0.512 rs139562 chr22:42196684 G/C cg06481639 chr22:41940642 POLR3H -0.67 -5.86 -0.47 3.97e-8 Vitiligo; TGCT cis rs9522267 0.535 rs9522291 chr13:112233761 T/C cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs7772486 0.790 rs2254283 chr6:146204289 T/C cg23711669 chr6:146136114 FBXO30 0.89 10.18 0.67 4.61e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2302045 1.000 rs34777851 chr2:242047530 G/T cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs10501293 0.746 rs7104602 chr11:43018295 C/T cg03447554 chr11:43094025 NA 0.44 6.32 0.49 4.2e-9 Cognitive performance; TGCT trans rs1814175 0.684 rs1827015 chr11:49585241 A/G cg11707556 chr5:10655725 ANKRD33B -0.4 -9.03 -0.63 2.77e-15 Height; TGCT cis rs28595532 0.541 rs56055826 chr4:119789424 T/A cg14228332 chr4:119757509 SEC24D 1.3 6.62 0.51 9.62e-10 Cannabis dependence symptom count; TGCT cis rs7769051 1.000 rs7765224 chr6:133101624 T/C cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs7829975 0.744 rs2409092 chr8:8682192 A/T cg08975724 chr8:8085496 FLJ10661 0.53 4.82 0.4 4.03e-6 Mood instability; TGCT cis rs4319547 1.000 rs9705654 chr12:123083508 T/C cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.44 -0.44 2.68e-7 Body mass index; TGCT cis rs2014572 0.967 rs8100154 chr19:57765432 A/G cg24459738 chr19:57751996 ZNF805 -0.58 -5.7 -0.46 8.38e-8 Hyperactive-impulsive symptoms; TGCT cis rs796364 0.806 rs11694236 chr2:200916230 T/C cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs7267979 0.903 rs6115101 chr20:25229564 C/A cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg04944784 chr2:26401820 FAM59B -0.73 -5.95 -0.47 2.61e-8 Gut microbiome composition (summer); TGCT cis rs2562456 0.833 rs516519 chr19:21481532 C/G cg25650185 chr19:21324782 ZNF431 0.54 4.52 0.38 1.41e-5 Pain; TGCT cis rs7119 0.717 rs11636529 chr15:77816220 T/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs2836974 0.831 rs4375956 chr21:40521788 G/A cg06238570 chr21:40685208 BRWD1 0.69 6.28 0.49 5.3300000000000004e-09 Cognitive function; TGCT cis rs2046867 0.862 rs35178407 chr3:72799703 C/T cg25664220 chr3:72788482 NA -0.55 -6.81 -0.52 3.66e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs3820068 0.581 rs6666373 chr1:15939884 A/T cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.26e-13 Systolic blood pressure; TGCT cis rs514406 0.505 rs6703127 chr1:53180565 C/T cg08859206 chr1:53392774 SCP2 -0.36 -5.22 -0.42 7.32e-7 Monocyte count; TGCT cis rs6088580 0.634 rs4911153 chr20:32961547 C/T cg08999081 chr20:33150536 PIGU -0.25 -4.86 -0.4 3.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs7769051 0.522 rs7761207 chr6:133110430 G/A cg22852734 chr6:133119734 C6orf192 1.22 4.65 0.39 8.32e-6 Type 2 diabetes nephropathy; TGCT cis rs7666738 0.830 rs6839203 chr4:98839814 C/G cg05340658 chr4:99064831 C4orf37 0.53 6.17 0.48 8.71e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7845219 0.544 rs7017487 chr8:95922752 A/G cg16049864 chr8:95962084 TP53INP1 0.48 5.3 0.43 5.23e-7 Type 2 diabetes; TGCT cis rs73198271 0.628 rs11777908 chr8:8590437 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12497850 0.931 rs7627404 chr3:48819668 A/C cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg04025307 chr7:1156635 C7orf50 0.21 5.15 0.42 9.79e-7 Longevity;Endometriosis; TGCT cis rs981844 1.000 rs2606332 chr4:154655372 G/A cg14289246 chr4:154710475 SFRP2 1.05 8.74 0.62 1.39e-14 Response to statins (LDL cholesterol change); TGCT cis rs597539 0.652 rs513359 chr11:68669496 A/T cg21963583 chr11:68658836 MRPL21 -0.36 -6.03 -0.48 1.71e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9303401 0.538 rs3785493 chr17:56472119 G/T cg10487724 chr17:56770010 TEX14;RAD51C -0.69 -6.1 -0.48 1.23e-8 Cognitive test performance; TGCT cis rs2075671 0.855 rs62483567 chr7:100286435 G/A cg20848291 chr7:100343083 ZAN -0.52 -4.52 -0.38 1.44e-5 Other erythrocyte phenotypes; TGCT cis rs1008375 0.898 rs10008445 chr4:17593978 G/T cg18681998 chr4:17616180 MED28 1.0 10.01 0.67 1.2e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11122272 0.675 rs1416913 chr1:231533206 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.53 -0.51 1.55e-9 Hemoglobin concentration; TGCT cis rs9894429 0.816 rs7406040 chr17:79597583 A/C cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs2033711 0.905 rs893186 chr19:58969179 C/A cg03735888 chr19:58951602 ZNF132 0.55 4.86 0.4 3.42e-6 Uric acid clearance; TGCT cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg11644478 chr21:40555479 PSMG1 1.02 11.05 0.7 3.46e-20 Cognitive function; TGCT cis rs2012796 0.661 rs59969857 chr14:81841579 A/G cg02996355 chr14:81879375 NA 0.53 5.28 0.43 5.55e-7 Night sleep phenotypes; TGCT cis rs11105298 0.891 rs11105313 chr12:89923376 A/T cg00757033 chr12:89920650 WDR51B -0.31 -4.91 -0.4 2.82e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs17741873 0.836 rs11000797 chr10:75628224 A/G cg07699608 chr10:75541558 CHCHD1 0.79 5.64 0.45 1.07e-7 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs7681440 0.904 rs6532193 chr4:90764188 G/A cg20003494 chr4:90757398 SNCA -0.63 -6.09 -0.48 1.3e-8 Dementia with Lewy bodies; TGCT cis rs4700695 1.000 rs111338 chr5:65420393 G/A cg21114390 chr5:65439923 SFRS12 -0.65 -5.02 -0.41 1.76e-6 Facial morphology (factor 19); TGCT cis rs854765 0.547 rs4925135 chr17:17952868 T/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs25645 0.830 rs3935281 chr17:38188419 C/T cg17467752 chr17:38218738 THRA -0.56 -5.08 -0.41 1.36e-6 Myeloid white cell count; TGCT cis rs736408 0.522 rs998909 chr3:52805093 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -4.88 -0.4 3.2e-6 Bipolar disorder; TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs7119 0.666 rs2516302 chr15:77879842 C/G cg27398640 chr15:77910606 LINGO1 0.3 6.22 0.49 7.06e-9 Type 2 diabetes; TGCT cis rs910316 0.763 rs4556 chr14:75476071 G/C cg11812906 chr14:75593930 NEK9 0.58 5.56 0.45 1.6e-7 Height; TGCT trans rs1814175 0.791 rs10219223 chr11:49791468 A/T cg03929089 chr4:120376271 NA -0.7 -8.19 -0.59 2.72e-13 Height; TGCT cis rs72945132 0.882 rs6592522 chr11:70128271 G/A cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs34014631 0.748 rs61874116 chr10:103611191 A/G cg22630918 chr10:102748988 C10orf2 0.34 4.56 0.38 1.21e-5 Coronary artery calcification; TGCT cis rs6906287 0.647 rs11753128 chr6:118853514 C/T cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs2841277 0.708 rs9671643 chr14:105408030 A/G cg19901468 chr14:105411992 AHNAK2 -0.27 -5.86 -0.47 3.84e-8 Rheumatoid arthritis; TGCT cis rs7975161 0.572 rs4964226 chr12:104570489 A/G cg25273343 chr12:104657179 TXNRD1 -0.31 -4.56 -0.38 1.22e-5 Toenail selenium levels; TGCT cis rs9467773 0.933 rs35355150 chr6:26526039 G/A cg15659132 chr6:26577336 NA 0.81 10.8 0.7 1.45e-19 Intelligence (multi-trait analysis); TGCT cis rs6500602 0.727 rs11644481 chr16:4581002 T/G cg09549813 chr16:4587862 C16orf5 -0.28 -4.5 -0.37 1.52e-5 Schizophrenia; TGCT cis rs1577917 0.958 rs12209259 chr6:86502348 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs56114371 0.568 rs200468 chr6:27757855 C/G cg10876282 chr6:28092338 ZSCAN16 0.57 4.54 0.38 1.32e-5 Breast cancer; TGCT cis rs4699052 1.000 rs7694190 chr4:104168017 A/G cg16532752 chr4:104119610 CENPE -0.62 -5.75 -0.46 6.64e-8 Testicular germ cell tumor; TGCT cis rs1577917 1.000 rs12208493 chr6:86662267 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs709400 0.633 rs1951391 chr14:103898313 T/C cg26031613 chr14:104095156 KLC1 0.84 9.31 0.64 5.77e-16 Body mass index; TGCT cis rs28595532 0.844 rs55845920 chr4:119490085 C/T cg11846333 chr4:119757529 SEC24D 0.93 5.08 0.42 1.32e-6 Cannabis dependence symptom count; TGCT cis rs2058350 1.000 rs7980501 chr12:3912972 C/T cg08553284 chr12:4381997 CCND2 -0.53 -4.44 -0.37 1.93e-5 Cognitive performance; TGCT cis rs1971762 0.563 rs10219725 chr12:54080865 T/G cg16917193 chr12:54089295 NA 1.39 17.73 0.85 8.5000000000000007e-36 Height; TGCT cis rs9926296 0.568 rs1230 chr16:89804855 A/G cg04287289 chr16:89883240 FANCA -0.94 -12.0 -0.73 1.7e-22 Vitiligo; TGCT cis rs12693043 0.727 rs10172858 chr2:175417011 C/T cg11778734 chr2:175439522 WIPF1 0.39 5.1 0.42 1.24e-6 Urate levels (BMI interaction); TGCT cis rs79349575 0.749 rs957557 chr17:47003221 G/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs28595532 0.920 rs114649974 chr4:119735341 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7267979 1.000 rs2258135 chr20:25272323 C/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2282802 0.685 rs62385161 chr5:139635747 T/C cg01081189 chr5:139537190 NA 0.29 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs7727544 0.545 rs10074490 chr5:131340032 C/T cg21474247 chr5:131268130 NA 0.34 4.6 0.38 1.05e-5 Blood metabolite levels; TGCT cis rs36405 1.000 rs36403 chr14:72358612 C/T cg10066683 chr14:71515513 PCNX -0.25 -4.84 -0.4 3.72e-6 Yang-deficiency constitution; TGCT cis rs9650657 0.738 rs11250078 chr8:10666581 G/A cg27411982 chr8:10470053 RP1L1 -0.23 -5.17 -0.42 9.17e-7 Neuroticism; TGCT cis rs546131 0.963 rs539044 chr11:34841542 G/T cg11058730 chr11:34937778 PDHX;APIP 0.5 4.52 0.38 1.42e-5 Lung disease severity in cystic fibrosis; TGCT cis rs2862064 0.745 rs4704733 chr5:156480104 T/G cg12943317 chr5:156479607 HAVCR1 -0.41 -5.32 -0.43 4.59e-7 Platelet count; TGCT cis rs9910055 0.529 rs228746 chr17:42173752 T/C cg19774624 chr17:42201019 HDAC5 0.65 5.87 0.47 3.67e-8 Total body bone mineral density; TGCT cis rs12118280 0.959 rs61799377 chr1:108741774 T/A cg11967332 chr1:108735228 SLC25A24 0.39 5.44 0.44 2.74e-7 Myeloid white cell count; TGCT cis rs854765 0.647 rs1008135 chr17:18027143 A/G cg04398451 chr17:18023971 MYO15A -0.39 -6.73 -0.52 5.54e-10 Total body bone mineral density; TGCT cis rs11785400 1.000 rs4557682 chr8:143738182 T/C cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs5769765 0.955 rs8138687 chr22:50291869 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.86 -0.73 3.71e-22 Schizophrenia; TGCT cis rs7523050 0.643 rs35438081 chr1:109402831 G/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT trans rs551517 0.541 rs494605 chr9:113644930 C/T cg18410444 chr5:89825535 LYSMD3 0.68 6.98 0.53 1.56e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs7666738 0.791 rs13125277 chr4:99009922 T/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12681287 0.752 rs13277670 chr8:87259920 T/G cg27223183 chr8:87520930 FAM82B -0.81 -5.66 -0.45 9.9e-8 Caudate activity during reward; TGCT cis rs6733011 0.506 rs11123755 chr2:99507948 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.78 -0.39 4.87e-6 Bipolar disorder; TGCT cis rs7772486 0.686 rs1292334 chr6:145968288 A/G cg13319975 chr6:146136371 FBXO30 -0.56 -5.13 -0.42 1.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7829975 0.686 rs907180 chr8:8702827 A/G cg06636001 chr8:8085503 FLJ10661 0.71 6.69 0.52 6.76e-10 Mood instability; TGCT cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2243480 0.901 rs778687 chr7:65835819 G/A cg20637647 chr7:64974828 NA 0.92 5.09 0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs2749592 0.550 rs9733309 chr10:37882405 G/A cg25427524 chr10:38739819 LOC399744 0.3 5.53 0.44 1.79e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs59197085 0.636 rs9791702 chr7:128440185 T/C cg00260937 chr7:128520193 KCP 0.48 5.02 0.41 1.77e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs9372498 0.536 rs9489447 chr6:118900846 G/A cg07617317 chr6:118971624 C6orf204 0.5 5.32 0.43 4.71e-7 Diastolic blood pressure; TGCT cis rs12478296 1.000 rs6743297 chr2:243013814 A/G cg06360820 chr2:242988706 NA -0.59 -4.77 -0.39 4.99e-6 Obesity-related traits; TGCT cis rs71435601 0.600 rs1652422 chr2:21383841 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs6558530 0.692 rs12335115 chr8:1699852 C/G cg09410841 chr8:1729607 CLN8 0.72 6.48 0.5 1.98e-9 Systolic blood pressure; TGCT cis rs4824093 0.610 rs58671506 chr22:50288983 G/A cg14114931 chr22:50943910 LMF2 0.37 4.58 0.38 1.11e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs11650494 0.908 rs74830554 chr17:47431950 G/A cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs36051895 0.664 rs11793659 chr9:5109707 A/G cg02405213 chr9:5042618 JAK2 -0.72 -9.48 -0.65 2.31e-16 Pediatric autoimmune diseases; TGCT cis rs1005277 0.579 rs2472175 chr10:38382901 T/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.2 -0.59 2.5e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1682825 1.000 rs73812286 chr3:10769921 C/G cg23512531 chr3:10780469 NA 0.69 4.75 0.39 5.43e-6 Economic and political preferences (feminism/equality); TGCT cis rs858239 0.932 rs199355 chr7:23296533 C/T cg05602783 chr7:23145260 KLHL7 -0.62 -5.06 -0.41 1.45e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs17741873 0.779 rs58125091 chr10:75605420 A/T cg07699608 chr10:75541558 CHCHD1 0.71 4.81 0.4 4.26e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs68170813 0.559 rs114221457 chr7:107019913 C/G cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs7715806 0.500 rs17563974 chr5:75004175 G/A cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs861020 0.630 rs657861 chr1:210006884 C/G cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs9914544 0.505 rs4924774 chr17:18794920 A/C cg26378065 chr17:18585709 ZNF286B 0.55 4.86 0.4 3.53e-6 Educational attainment (years of education); TGCT cis rs1887596 0.705 rs665816 chr13:27228538 T/C cg01312412 chr13:27282625 NA 0.28 4.99 0.41 1.96e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs6430585 0.583 rs2304370 chr2:136561735 G/A cg07169764 chr2:136633963 MCM6 1.05 10.03 0.67 1.09e-17 Corneal structure; TGCT cis rs910316 0.763 rs175044 chr14:75472109 G/A cg08847533 chr14:75593920 NEK9 -0.84 -8.92 -0.63 5.19e-15 Height; TGCT cis rs10986311 0.832 rs10818951 chr9:127131062 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 0.2 4.71 0.39 6.55e-6 Vitiligo; TGCT cis rs78487399 0.808 rs13419380 chr2:43739184 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs561341 1.000 rs55959993 chr17:30254771 C/G cg20587970 chr11:113659929 NA -1.03 -10.94 -0.7 6.67e-20 Hip circumference adjusted for BMI; TGCT cis rs6714710 0.603 rs1875699 chr2:98580724 G/T cg26665480 chr2:98280029 ACTR1B 0.63 5.98 0.47 2.19e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7940866 0.804 rs6590540 chr11:130805444 T/C cg05962950 chr11:130786565 SNX19 0.67 6.64 0.51 8.71e-10 Schizophrenia; TGCT cis rs7818688 0.697 rs11781397 chr8:95974506 G/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs854765 0.618 rs9908017 chr17:17774422 C/T cg09796270 chr17:17721594 SREBF1 -0.24 -4.78 -0.39 4.77e-6 Total body bone mineral density; TGCT cis rs9473924 0.542 rs9473925 chr6:50834565 T/C cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs875971 0.825 rs1000464 chr7:65777909 G/C cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs2013441 0.965 rs6587063 chr17:20193940 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs2832191 0.716 rs7509628 chr21:30454252 C/T cg08807101 chr21:30365312 RNF160 0.65 6.14 0.48 1.03e-8 Dental caries; TGCT cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs10791097 0.694 rs7106973 chr11:130758113 G/A cg12179176 chr11:130786555 SNX19 0.87 10.65 0.69 3.29e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs79057730 0.599 rs35928068 chr7:805363 G/C cg11064039 chr7:766100 PRKAR1B;HEATR2 0.76 5.84 0.46 4.31e-8 Initial pursuit acceleration; TGCT cis rs4555082 0.874 rs3000075 chr14:105713219 C/T cg01266790 chr14:105781312 PACS2 -0.53 -4.49 -0.37 1.6e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.28e-17 Electroencephalogram traits; TGCT cis rs9393692 0.645 rs2179152 chr6:26325888 T/C cg13736514 chr6:26305472 NA -0.45 -6.67 -0.51 7.52e-10 Educational attainment; TGCT cis rs8072100 0.905 rs9895274 chr17:45539117 C/T cg08085267 chr17:45401833 C17orf57 -0.46 -4.99 -0.41 1.98e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT trans rs62295889 1.000 rs62293733 chr4:12594002 T/C cg01948047 chr22:19724501 NA 0.69 7.25 0.55 4.03e-11 Obesity-related traits; TGCT cis rs1971762 0.523 rs3852562 chr12:54085750 T/C cg16917193 chr12:54089295 NA 1.38 18.38 0.86 3.23e-37 Height; TGCT cis rs9534288 0.730 rs2148412 chr13:46595849 C/T cg15192986 chr13:46630673 CPB2 -0.49 -6.92 -0.53 2.11e-10 Blood protein levels; TGCT cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs8031584 0.678 rs8035703 chr15:31168472 T/C cg08704250 chr15:31115839 NA -0.43 -6.31 -0.49 4.47e-9 Huntington's disease progression; TGCT cis rs7072216 0.763 rs7909822 chr10:100172035 A/C cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg04546413 chr19:29218101 NA 0.83 6.74 0.52 5.35e-10 Methadone dose in opioid dependence; TGCT cis rs3096299 0.967 rs2965932 chr16:89477051 C/T cg06640241 chr16:89574553 SPG7 -0.65 -6.28 -0.49 5.18e-9 Multiple myeloma (IgH translocation); TGCT cis rs7178424 0.606 rs17271151 chr15:62140189 A/C cg00456672 chr15:62358751 C2CD4A -0.29 -4.5 -0.37 1.56e-5 Height; TGCT cis rs12210905 0.610 rs80328528 chr6:27595604 T/A cg08851530 chr6:28072375 NA 1.33 6.25 0.49 6.17e-9 Hip circumference adjusted for BMI; TGCT cis rs137699 1.000 rs2413588 chr22:39755175 A/G cg24399712 chr22:39784796 NA -0.63 -5.63 -0.45 1.16e-7 IgG glycosylation; TGCT cis rs8180040 0.966 rs11130128 chr3:47486632 T/C cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs1395 1.000 rs1659685 chr2:27420690 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.49 -6.62 -0.51 9.77e-10 Blood metabolite levels; TGCT cis rs12142240 0.698 rs1475390 chr1:46816340 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs709400 0.628 rs10150072 chr14:103977605 C/T cg12935359 chr14:103987150 CKB -0.38 -5.7 -0.46 8.3e-8 Body mass index; TGCT trans rs7819412 0.806 rs2898256 chr8:10932695 G/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.04 -0.53 1.14e-10 Triglycerides; TGCT cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg06238570 chr21:40685208 BRWD1 -0.61 -6.3 -0.49 4.75e-9 Menarche (age at onset); TGCT cis rs35160687 0.901 rs34048420 chr2:86529748 A/G cg04877910 chr2:85804641 VAMP8 0.34 4.51 0.38 1.49e-5 Night sleep phenotypes; TGCT cis rs933688 1.000 rs10073657 chr5:90689749 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 9.43 0.65 2.97e-16 Smoking behavior; TGCT cis rs7552404 0.961 rs1061337 chr1:76227022 A/G cg22875332 chr1:76189707 ACADM 0.77 8.97 0.63 3.96e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3806843 0.606 rs251377 chr5:140255792 C/A cg07102913 chr5:140593443 PCDHB13 0.49 4.71 0.39 6.4e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9911578 0.967 rs9907940 chr17:56663842 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7223966 1.000 rs7209435 chr17:61712964 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.76 0.39 5.24e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs62244186 0.627 rs3935212 chr3:44460954 G/A cg15687855 chr3:44754131 ZNF502 -0.42 -5.06 -0.41 1.46e-6 Depressive symptoms; TGCT trans rs210152 0.531 rs3130023 chr6:33448862 A/G cg08795360 chr21:41033440 B3GALT5 -0.45 -7.17 -0.54 5.98e-11 Schizophrenia; TGCT cis rs28595532 0.748 rs17594978 chr4:119336398 T/C cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs2456568 0.564 rs6483270 chr11:93624380 C/T cg16099599 chr11:93583650 C11orf90 -0.38 -4.44 -0.37 1.99e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs910316 0.737 rs175077 chr14:75506875 G/A cg11812906 chr14:75593930 NEK9 -0.63 -5.85 -0.47 4.1e-8 Height; TGCT cis rs7666738 0.830 rs10007261 chr4:98926155 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs77106637 0.932 rs74439784 chr11:72649396 A/T cg03713592 chr11:72463424 ARAP1 0.87 5.87 0.47 3.74e-8 Type 2 diabetes; TGCT cis rs9517313 0.591 rs17574543 chr13:99172893 G/A cg07423050 chr13:99094983 FARP1 -0.31 -5.98 -0.47 2.26e-8 Neuroticism; TGCT cis rs9527 0.615 rs1556960 chr10:104726673 A/G cg04362960 chr10:104952993 NT5C2 0.66 5.64 0.45 1.1e-7 Arsenic metabolism; TGCT cis rs1059312 0.808 rs2306683 chr12:129299675 C/G cg09035930 chr12:129282057 SLC15A4 0.56 9.95 0.67 1.71e-17 Systemic lupus erythematosus; TGCT cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg14004847 chr7:1930337 MAD1L1 -0.28 -4.71 -0.39 6.44e-6 Bipolar disorder and schizophrenia; TGCT cis rs12765878 1.000 rs34300861 chr10:105643332 A/C cg11005552 chr10:105648138 OBFC1 0.44 7.6 0.56 6.24e-12 Coronary artery disease; TGCT cis rs669446 0.533 rs28833034 chr1:44212942 A/G cg12908607 chr1:44402522 ARTN -0.63 -7.43 -0.56 1.52e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs6940638 1.000 rs6940638 chr6:27046250 A/G cg16898833 chr6:26189333 HIST1H4D 0.75 5.77 0.46 5.93e-8 Intelligence (multi-trait analysis); TGCT cis rs7843479 1.000 rs13248727 chr8:21842063 T/C cg17168535 chr8:21777572 XPO7 0.63 5.73 0.46 7.05e-8 Mean corpuscular volume; TGCT cis rs7937612 1.000 rs7104639 chr11:120239456 C/G cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.7 -0.39 6.76e-6 Intraocular pressure; TGCT cis rs7917772 0.636 rs7897384 chr10:104529042 T/G cg05855489 chr10:104503620 C10orf26 0.61 4.92 0.4 2.71e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg17971929 chr21:40555470 PSMG1 -0.7 -6.53 -0.51 1.55e-9 Cognitive function; TGCT cis rs7727544 0.735 rs274559 chr5:131720070 A/G cg14196790 chr5:131705035 SLC22A5 -0.32 -4.51 -0.38 1.46e-5 Blood metabolite levels; TGCT cis rs2115630 0.691 rs2292462 chr15:85200754 G/T cg11189052 chr15:85197271 WDR73 -0.69 -6.58 -0.51 1.2e-9 P wave terminal force; TGCT cis rs4718428 0.705 rs3800817 chr7:66263550 T/A cg18252515 chr7:66147081 NA -0.59 -4.52 -0.38 1.44e-5 Corneal structure; TGCT cis rs752010 0.655 rs10890145 chr1:42086290 A/G cg06885757 chr1:42089581 HIVEP3 0.25 4.56 0.38 1.23e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs3008870 1.000 rs1925412 chr1:67405057 G/A cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.97 0.73 2.07e-22 Lymphocyte percentage of white cells; TGCT cis rs9372498 0.536 rs9489467 chr6:118935206 C/T cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs2404602 0.692 rs3110382 chr15:77148688 G/A cg26408565 chr15:76604113 ETFA 0.36 4.56 0.38 1.23e-5 Blood metabolite levels; TGCT cis rs3008870 1.000 rs3008854 chr1:67385951 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs910316 0.935 rs2268620 chr14:75640403 G/A cg08847533 chr14:75593920 NEK9 -0.93 -10.14 -0.67 5.65e-18 Height; TGCT cis rs2228479 0.850 rs17233664 chr16:89810628 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs34779708 0.931 rs4934709 chr10:35339324 A/C cg05301181 chr10:35379533 CUL2 -0.53 -4.69 -0.39 7.06e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs1949733 0.628 rs1543246 chr4:8504909 A/T cg11789530 chr4:8429930 ACOX3 0.47 4.58 0.38 1.11e-5 Response to antineoplastic agents; TGCT cis rs7923609 0.967 rs4454603 chr10:65012750 C/T cg08743896 chr10:65200160 JMJD1C -0.34 -4.54 -0.38 1.32e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT trans rs208520 1.000 rs72884017 chr6:66992513 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs7829975 0.840 rs555617 chr8:8592845 C/G cg06636001 chr8:8085503 FLJ10661 -0.56 -4.61 -0.38 9.79e-6 Mood instability; TGCT cis rs909674 0.818 rs8137426 chr22:39844350 T/G cg02038168 chr22:39784481 NA -0.73 -5.59 -0.45 1.39e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs7523273 0.564 rs1570565 chr1:207881256 G/A cg22525895 chr1:207977042 MIR29B2 0.29 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs12620999 0.941 rs13005377 chr2:238037759 T/C cg23555395 chr2:238036564 NA -0.31 -5.51 -0.44 2.02e-7 Systemic lupus erythematosus; TGCT cis rs896854 0.552 rs2515236 chr8:95934907 A/G cg09323728 chr8:95962352 TP53INP1 0.42 4.8 0.4 4.49e-6 Type 2 diabetes; TGCT cis rs7044106 0.762 rs7849566 chr9:123460769 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.57 0.38 1.16e-5 Hip circumference adjusted for BMI; TGCT cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6547741 0.788 rs7595739 chr2:27874563 G/T cg27432699 chr2:27873401 GPN1 -0.24 -6.14 -0.48 1.04e-8 Oral cavity cancer; TGCT cis rs1971256 0.500 rs3912291 chr6:151818210 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.8 -4.77 -0.39 5.14e-6 Endometriosis; TGCT cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs8077577 0.895 rs1563373 chr17:18114228 G/A cg09161412 chr17:18057145 MYO15A -0.6 -4.79 -0.4 4.61e-6 Obesity-related traits; TGCT trans rs1005277 0.522 rs11011343 chr10:38002698 A/G cg17830980 chr10:43048298 ZNF37B -0.65 -7.34 -0.55 2.4e-11 Extrinsic epigenetic age acceleration; TGCT cis rs8177253 0.930 rs12595 chr3:133496553 T/C cg08048268 chr3:133502702 NA -0.65 -9.77 -0.66 4.57e-17 Iron status biomarkers; TGCT cis rs9527 0.590 rs1926029 chr10:104855670 C/T cg15744005 chr10:104629667 AS3MT -0.44 -5.08 -0.42 1.33e-6 Arsenic metabolism; TGCT cis rs344364 0.518 rs1657129 chr16:1945826 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9914988 1.000 rs9895443 chr17:27182944 A/G cg20469991 chr17:27169893 C17orf63 -0.69 -5.05 -0.41 1.51e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2404602 1.000 rs4886818 chr15:76880939 G/A cg26408565 chr15:76604113 ETFA -0.38 -4.82 -0.4 4.03e-6 Blood metabolite levels; TGCT cis rs9902453 1.000 rs12600993 chr17:28291222 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 6.61 0.51 1.01e-9 Coffee consumption (cups per day); TGCT trans rs7819412 0.740 rs28633434 chr8:11053922 G/A cg15556689 chr8:8085844 FLJ10661 -0.76 -7.32 -0.55 2.7e-11 Triglycerides; TGCT cis rs2921036 0.529 rs2979192 chr8:8338147 C/T cg15556689 chr8:8085844 FLJ10661 0.62 5.5 0.44 2.04e-7 Neuroticism; TGCT cis rs10751667 0.621 rs10794348 chr11:939941 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT trans rs1814175 0.817 rs1851860 chr11:49861310 A/C cg03929089 chr4:120376271 NA -0.7 -8.05 -0.59 5.64e-13 Height; TGCT cis rs854765 0.552 rs11078407 chr17:17841083 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.72 0.57 3.31e-12 Total body bone mineral density; TGCT cis rs908922 0.676 rs908927 chr1:152513338 C/G cg20991723 chr1:152506922 NA 0.45 6.16 0.48 9.53e-9 Hair morphology; TGCT cis rs2404602 0.647 rs11855296 chr15:77092962 C/T cg22467129 chr15:76604101 ETFA 0.48 4.71 0.39 6.51e-6 Blood metabolite levels; TGCT cis rs826838 0.874 rs10880943 chr12:38734317 C/T cg26384229 chr12:38710491 ALG10B 1.08 10.88 0.7 9.18e-20 Heart rate; TGCT cis rs651907 0.557 rs7612283 chr3:101434919 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.73 0.39 5.91e-6 Colorectal cancer; TGCT cis rs7246657 0.943 rs1015848 chr19:37945274 A/C cg18154014 chr19:37997991 ZNF793 0.95 6.63 0.51 9.39e-10 Coronary artery calcification; TGCT cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg17971929 chr21:40555470 PSMG1 0.95 9.07 0.63 2.19e-15 Cognitive function; TGCT cis rs6089584 0.586 rs2296087 chr20:60584328 T/A cg06108461 chr20:60628389 TAF4 -0.42 -5.2 -0.42 8.11e-7 Body mass index; TGCT cis rs698813 0.604 rs7606004 chr2:44479983 G/A cg00619915 chr2:44497795 NA -0.24 -5.62 -0.45 1.19e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs9419702 0.538 rs4074772 chr10:133540006 A/T cg23460707 chr10:133558971 NA 0.44 4.94 0.41 2.46e-6 Survival in rectal cancer; TGCT cis rs2230307 0.505 rs482873 chr1:100589757 C/T cg24955406 chr1:100503596 HIAT1 -0.75 -5.11 -0.42 1.2e-6 Carotid intima media thickness; TGCT cis rs1568889 1.000 rs35697240 chr11:28287342 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.8 0.62 9.95e-15 Bipolar disorder; TGCT cis rs4819052 1.000 rs4818769 chr21:46667451 C/T cg06618935 chr21:46677482 NA -0.37 -4.97 -0.41 2.13e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9650657 0.589 rs12542037 chr8:10758496 G/A cg21775007 chr8:11205619 TDH 0.49 4.46 0.37 1.84e-5 Neuroticism; TGCT cis rs7226408 0.857 rs72887029 chr18:34471969 A/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2197308 0.565 rs12809769 chr12:37909968 C/T cg26384229 chr12:38710491 ALG10B 0.89 7.98 0.58 8.43e-13 Morning vs. evening chronotype; TGCT cis rs2456568 0.867 rs2462744 chr11:93682913 G/A cg14065697 chr11:93583672 C11orf90 -0.38 -4.58 -0.38 1.13e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7655441 0.964 rs6534693 chr4:80906214 T/A cg02241357 chr4:80885279 ANTXR2 -0.24 -4.59 -0.38 1.07e-5 Neutrophil percentage of white cells; TGCT cis rs2295359 1.000 rs11209007 chr1:67619345 C/G cg03340356 chr1:67600835 NA 0.36 4.55 0.38 1.24e-5 Psoriasis; TGCT cis rs7731657 0.537 rs4705851 chr5:130220592 A/G cg08523029 chr5:130500466 HINT1 0.61 5.07 0.41 1.4e-6 Fasting plasma glucose; TGCT cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11190604 0.767 rs7916904 chr10:102186778 C/G cg23241863 chr10:102295624 HIF1AN 0.62 4.79 0.4 4.69e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs881375 0.933 rs2239657 chr9:123671520 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.49 -5.5 -0.44 2.09e-7 Rheumatoid arthritis; TGCT cis rs10892173 0.678 rs4537790 chr11:117661356 A/G cg07621104 chr11:117668040 DSCAML1 0.54 5.55 0.45 1.65e-7 Myopia; TGCT cis rs9611565 0.592 rs5751129 chr22:42015765 C/T cg06634786 chr22:41940651 POLR3H 0.83 7.91 0.58 1.2e-12 Vitiligo; TGCT trans rs916888 0.647 rs199449 chr17:44808902 G/A cg22433210 chr17:43662623 NA 0.96 7.94 0.58 1.03e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg06634786 chr22:41940651 POLR3H -0.91 -8.85 -0.62 7.39e-15 Vitiligo; TGCT cis rs2637266 1.000 rs7477433 chr10:78358116 C/T cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs10838634 1.000 rs56331152 chr11:46885016 C/T cg18332754 chr11:46939436 LRP4 0.89 4.77 0.39 5.13e-6 Schizophrenia; TGCT cis rs6088590 0.965 rs6058108 chr20:33288655 A/G cg08999081 chr20:33150536 PIGU 0.26 4.6 0.38 1.03e-5 Coronary artery disease; TGCT cis rs1723838 0.702 rs1623476 chr11:73581224 C/T cg18195628 chr11:73498948 MRPL48 0.92 5.05 0.41 1.57e-6 Obesity-related traits; TGCT cis rs40363 0.951 rs72778117 chr16:3531827 T/C cg22508957 chr16:3507546 NAT15 0.54 5.04 0.41 1.59e-6 Tuberculosis; TGCT cis rs6754311 0.564 rs1960171 chr2:136815388 C/T cg07169764 chr2:136633963 MCM6 0.58 5.23 0.43 7.03e-7 Mosquito bite size; TGCT cis rs2235642 0.928 rs1057610 chr16:1605537 T/C cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.26 -0.43 6.24e-7 Coronary artery disease; TGCT cis rs78707713 0.592 rs3829182 chr10:71251384 A/G cg12610070 chr10:71211762 TSPAN15 -0.62 -7.39 -0.55 1.91e-11 Venous thromboembolism; TGCT cis rs875971 0.862 rs11984115 chr7:65773859 C/T cg11764359 chr7:65958608 NA -0.55 -5.0 -0.41 1.94e-6 Aortic root size; TGCT cis rs7959452 0.535 rs11615712 chr12:69619736 A/T cg14784868 chr12:69753453 YEATS4 -0.67 -6.7 -0.52 6.61e-10 Blood protein levels; TGCT cis rs10782582 0.593 rs11163915 chr1:76130199 C/T cg03433033 chr1:76189801 ACADM -0.63 -7.25 -0.55 3.83e-11 Daytime sleep phenotypes; TGCT cis rs929354 0.772 rs1182364 chr7:157017912 T/C cg05182265 chr7:156933206 UBE3C 0.4 9.08 0.63 2.11e-15 Body mass index; TGCT cis rs55883249 1.000 rs57234614 chr2:9756379 T/C cg23886495 chr2:9695866 ADAM17 0.8 4.72 0.39 6.38e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs854765 0.547 rs7209003 chr17:17907393 T/A cg09796270 chr17:17721594 SREBF1 0.24 4.83 0.4 4.03e-6 Total body bone mineral density; TGCT cis rs9534288 0.830 rs2296641 chr13:46632226 A/C cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs10788264 0.518 rs1028632 chr10:124044657 C/G cg09507567 chr10:124027408 NA 0.33 4.72 0.39 6.3e-6 Total body bone mineral density; TGCT cis rs7654585 1.000 rs4692025 chr4:25949759 A/C cg10409131 chr4:25915609 C4orf52 -0.69 -7.03 -0.53 1.23e-10 Obesity-related traits; TGCT cis rs910316 0.810 rs77939209 chr14:75670070 A/G cg11812906 chr14:75593930 NEK9 -0.66 -6.46 -0.5 2.17e-9 Height; TGCT cis rs6570726 0.791 rs6912079 chr6:145894949 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.85 0.66 2.95e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs3540 1.000 rs6496678 chr15:91034456 A/G cg22089800 chr15:90895588 ZNF774 0.78 7.9 0.58 1.27e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2952156 0.883 rs1495100 chr17:37832279 C/T cg20243544 chr17:37824526 PNMT 0.51 4.47 0.37 1.74e-5 Asthma; TGCT cis rs7772486 0.875 rs9322043 chr6:146352690 A/G cg05347473 chr6:146136440 FBXO30 0.55 5.23 0.43 6.86e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4851254 0.618 rs7572939 chr2:100654914 A/G cg07810366 chr2:100720526 AFF3 -0.47 -4.75 -0.39 5.46e-6 Intelligence (multi-trait analysis); TGCT cis rs11030122 0.547 rs10767721 chr11:3953411 G/C cg18678763 chr11:4115507 RRM1 -0.39 -4.76 -0.39 5.24e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs2067615 0.524 rs9804754 chr12:107083031 G/A cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs9291683 0.605 rs73224439 chr4:10331818 C/A cg11266682 chr4:10021025 SLC2A9 -0.5 -5.75 -0.46 6.44e-8 Bone mineral density; TGCT cis rs902774 0.585 rs7399070 chr12:53355678 G/T cg05393297 chr12:53359155 NA -0.85 -5.44 -0.44 2.73e-7 Prostate cancer; TGCT cis rs7715806 0.500 rs72633986 chr5:75006449 T/A cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs9486719 1.000 rs2273622 chr6:97058567 A/G cg18709589 chr6:96969512 KIAA0776 -0.78 -5.55 -0.45 1.63e-7 Migraine;Coronary artery disease; TGCT cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg19774624 chr17:42201019 HDAC5 -0.87 -10.64 -0.69 3.48e-19 Total body bone mineral density; TGCT cis rs877282 0.945 rs12767287 chr10:787310 A/G cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs2797160 0.714 rs1777220 chr6:126022602 G/T cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.07e-9 Endometrial cancer; TGCT cis rs765787 0.530 rs2413785 chr15:45530381 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg22168489 chr12:122356033 WDR66 0.2 4.7 0.39 6.72e-6 Mean corpuscular volume; TGCT cis rs2120019 0.938 rs5020842 chr15:75322310 T/C cg17294928 chr15:75287854 SCAMP5 -0.89 -6.84 -0.52 3.22e-10 Blood trace element (Zn levels); TGCT cis rs7267979 1.000 rs6050565 chr20:25347563 A/C cg16686733 chr20:25566563 NINL -0.59 -6.08 -0.48 1.39e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs950169 0.840 rs62019457 chr15:85102142 T/C cg12863693 chr15:85201151 NMB 0.41 4.63 0.38 9.27e-6 Schizophrenia; TGCT cis rs6964587 0.967 rs6465341 chr7:91596121 G/C cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs7772486 0.655 rs2142981 chr6:146071695 G/C cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11614913 0.509 rs12300425 chr12:54395082 G/T cg25285794 chr12:54402699 HOXC8 -0.64 -5.49 -0.44 2.16e-7 Waist circumference adjusted for body mass index; TGCT cis rs1865760 0.786 rs2164487 chr6:25950800 A/C cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT cis rs2982552 0.873 rs3020303 chr6:152064454 T/C cg22157087 chr6:152012887 ESR1 0.21 4.92 0.4 2.65e-6 Bone properties (heel); TGCT cis rs9549260 0.755 rs2755216 chr13:41156938 G/A cg21288729 chr13:41239152 FOXO1 1.02 10.62 0.69 3.83e-19 Red blood cell count; TGCT cis rs6088580 0.634 rs6088508 chr20:33060081 A/G cg06115741 chr20:33292138 TP53INP2 0.52 4.47 0.37 1.75e-5 Glomerular filtration rate (creatinine); TGCT cis rs7809950 1.000 rs17154104 chr7:107090698 C/T cg23024343 chr7:107201750 COG5 -0.34 -5.37 -0.43 3.73e-7 Coronary artery disease; TGCT cis rs7208859 0.673 rs1347359 chr17:28914529 T/C cg13385521 chr17:29058706 SUZ12P 0.7 4.48 0.37 1.69e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs34816374 1 rs34816374 chr6:26949672 A/G cg12315302 chr6:26189340 HIST1H4D 0.93 4.48 0.37 1.71e-5 Lung cancer in ever smokers; TGCT cis rs9300255 0.663 rs7953929 chr12:123758235 C/G cg00376283 chr12:123451042 ABCB9 0.63 4.59 0.38 1.09e-5 Neutrophil percentage of white cells; TGCT cis rs7043114 0.525 rs1053441 chr9:95147840 T/A cg14631576 chr9:95140430 CENPP -0.29 -4.79 -0.39 4.76e-6 Height; TGCT cis rs763014 0.966 rs4984903 chr16:680695 A/G cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.12e-6 Height; TGCT trans rs2727020 0.553 rs4103567 chr11:49255389 C/T cg03929089 chr4:120376271 NA -0.6 -6.75 -0.52 5.08e-10 Coronary artery disease; TGCT cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg10802521 chr3:52805072 NEK4 -0.7 -8.67 -0.61 2.04e-14 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs2084881 0.521 rs1022088 chr17:46579790 T/A cg25732028 chr17:46619313 NA -0.31 -4.54 -0.38 1.34e-5 Ovarian cancer; TGCT cis rs7924176 0.668 rs7895133 chr10:76007455 A/T cg19889307 chr10:75911429 ADK;AP3M1 -0.47 -4.56 -0.38 1.22e-5 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs2760061 0.655 rs686533 chr1:228119604 A/G cg18477163 chr1:228402036 OBSCN -0.32 -6.44 -0.5 2.38e-9 Diastolic blood pressure; TGCT cis rs9467711 0.591 rs9461219 chr6:25836927 C/G cg16898833 chr6:26189333 HIST1H4D -1.21 -5.94 -0.47 2.64e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs597539 0.616 rs631001 chr11:68642974 C/T cg21862992 chr11:68658383 NA 0.46 6.37 0.5 3.37e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12477438 0.501 rs2516833 chr2:99777405 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs2839186 0.681 rs13047198 chr21:47701835 T/C cg12516959 chr21:47718080 NA -0.32 -4.64 -0.38 8.8e-6 Testicular germ cell tumor; TGCT cis rs3087591 0.960 rs2285812 chr17:29533871 A/G cg24425628 chr17:29625626 OMG;NF1 0.46 7.04 0.53 1.17e-10 Hip circumference; TGCT cis rs617219 0.698 rs72764988 chr5:78533584 G/C cg05890484 chr5:78407552 BHMT 0.38 5.17 0.42 9.01e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4689388 0.926 rs5018648 chr4:6292818 C/G cg14416269 chr4:6271139 WFS1 -0.36 -4.8 -0.4 4.5e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs57994353 0.568 rs10747043 chr9:139318310 G/A cg13741927 chr9:139327495 INPP5E -0.24 -5.59 -0.45 1.37e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg20999797 chr1:1681921 NA 0.19 5.06 0.41 1.5e-6 Body mass index; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs2243480 1.000 rs4718269 chr7:65200778 C/G cg20637647 chr7:64974828 NA -0.9 -5.06 -0.41 1.45e-6 Diabetic kidney disease; TGCT cis rs6089829 0.851 rs6122346 chr20:61661822 C/G cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs858239 0.601 rs764534 chr7:23153935 C/T cg05602783 chr7:23145260 KLHL7 -0.71 -6.11 -0.48 1.2e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs10927875 0.619 rs2102664 chr1:16130169 A/G cg21385522 chr1:16154831 NA -0.74 -8.95 -0.63 4.33e-15 Dilated cardiomyopathy; TGCT cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg09904177 chr6:26538194 HMGN4 0.68 6.36 0.5 3.55e-9 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs62346506 chr5:201594 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.73 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs72615157 0.561 rs113844570 chr7:99873778 A/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.82 0.4 4.1e-6 Lung function (FEV1/FVC); TGCT cis rs2228479 0.850 rs34033205 chr16:89922959 G/T cg06558623 chr16:89946397 TCF25 0.55 4.83 0.4 3.89e-6 Skin colour saturation; TGCT cis rs513349 1.000 rs513349 chr6:33541719 A/G cg07679836 chr6:33548423 BAK1 0.32 4.77 0.39 4.98e-6 Platelet count; TGCT cis rs12893668 0.572 rs7148857 chr14:104143237 C/G cg26031613 chr14:104095156 KLC1 -0.6 -5.09 -0.42 1.32e-6 Reticulocyte count; TGCT cis rs10927875 0.832 rs4661342 chr1:16160773 C/G cg14742211 chr1:16348397 CLCNKA -0.2 -4.5 -0.37 1.55e-5 Dilated cardiomyopathy; TGCT cis rs7267979 0.714 rs1555329 chr20:25231858 G/A cg03522245 chr20:25566470 NINL 0.48 4.59 0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3087591 0.960 rs4559963 chr17:29438558 G/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.3 0.55 3.03e-11 Hip circumference; TGCT cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT trans rs4650994 0.525 rs4650996 chr1:178517365 A/G cg05059571 chr16:84539110 KIAA1609 -0.54 -11.05 -0.7 3.43e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs34638657 0.732 rs61111557 chr16:82201102 A/C cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs1801251 1.000 rs1022330 chr2:233577330 G/A cg08000102 chr2:233561755 GIGYF2 0.66 6.73 0.52 5.67e-10 Coronary artery disease; TGCT cis rs3008870 0.959 rs2985810 chr1:67376162 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.08 0.74 1.11e-22 Lymphocyte percentage of white cells; TGCT cis rs227917 1.000 rs10269243 chr7:23686785 A/G cg12601843 chr7:23510954 IGF2BP3 0.64 4.97 0.41 2.18e-6 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs7681440 0.904 rs7698219 chr4:90771351 C/A cg20003494 chr4:90757398 SNCA -0.59 -5.52 -0.44 1.9e-7 Dementia with Lewy bodies; TGCT cis rs3813359 0.614 rs12202427 chr6:130703231 G/T cg25049486 chr6:130544510 SAMD3 0.39 4.66 0.39 7.91e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs13118159 0.872 rs4974605 chr4:1346389 C/G cg22683308 chr4:1340831 KIAA1530 -0.65 -6.09 -0.48 1.32e-8 Longevity; TGCT cis rs751728 0.605 rs1535950 chr6:33785827 A/G cg13859433 chr6:33739653 LEMD2 -0.31 -5.45 -0.44 2.61e-7 Crohn's disease; TGCT cis rs854765 0.663 rs3744113 chr17:17748645 T/C cg09796270 chr17:17721594 SREBF1 -0.28 -5.43 -0.44 2.91e-7 Total body bone mineral density; TGCT cis rs931127 0.658 rs7926512 chr11:65464487 T/A cg17480646 chr11:65405466 SIPA1 -0.42 -5.36 -0.43 3.9e-7 Systemic lupus erythematosus; TGCT cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg07061783 chr6:25882402 NA -0.57 -5.59 -0.45 1.37e-7 Intelligence (multi-trait analysis); TGCT cis rs7647973 1.000 rs4241407 chr3:49600319 C/T cg05785598 chr3:49045655 WDR6 0.38 4.6 0.38 1.02e-5 Menarche (age at onset); TGCT cis rs7590720 0.704 rs7603645 chr2:216876949 C/G cg12620499 chr2:216877984 MREG 0.92 12.08 0.74 1.12e-22 Alcohol dependence; TGCT cis rs4494114 0.967 rs1925677 chr1:39346905 T/G cg25970120 chr1:39325951 RRAGC -0.54 -5.55 -0.45 1.65e-7 Blood protein levels; TGCT cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg09222892 chr1:25734099 RHCE -0.41 -6.72 -0.52 5.98e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs3617 0.625 rs11922961 chr3:52868610 T/C cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3784262 0.565 rs4646606 chr15:58287526 A/G cg12031962 chr15:58353849 ALDH1A2 0.37 5.24 0.43 6.8e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9473924 0.542 rs35546156 chr6:50829785 C/T cg14470998 chr6:50812995 TFAP2B 1.33 7.94 0.58 1.05e-12 Body mass index; TGCT cis rs9921338 0.961 rs7198849 chr16:11373301 C/T cg00044050 chr16:11439710 C16orf75 -0.76 -5.61 -0.45 1.24e-7 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg08859206 chr1:53392774 SCP2 -0.41 -6.12 -0.48 1.11e-8 Monocyte count; TGCT cis rs2072499 0.966 rs887953 chr1:156191149 T/C cg24450063 chr1:156163899 SLC25A44 1.2 14.13 0.79 1.31e-27 Testicular germ cell tumor; TGCT cis rs2562456 0.876 rs62110202 chr19:21754601 C/T cg25650185 chr19:21324782 ZNF431 -0.62 -5.13 -0.42 1.1e-6 Pain; TGCT cis rs483180 0.855 rs562038 chr1:120254545 G/C cg19096424 chr1:120255104 PHGDH 0.6 5.57 0.45 1.48e-7 Macular telangiectasia type 2; TGCT cis rs8031584 0.723 rs11632229 chr15:31179534 A/G cg14829155 chr15:31115871 NA 0.36 4.69 0.39 7.16e-6 Huntington's disease progression; TGCT cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg07636037 chr3:49044803 WDR6 0.85 8.88 0.62 6.21e-15 Menarche (age at onset); TGCT cis rs492146 0.765 rs419427 chr6:52844886 T/A cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs8078723 0.738 rs3816472 chr17:38142677 A/C cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.69e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs250677 0.652 rs36045 chr5:148441184 A/G cg23229984 chr5:148520753 ABLIM3 -0.22 -4.97 -0.41 2.14e-6 Breast cancer; TGCT trans rs10802346 0.545 rs4607841 chr1:246373295 T/C cg13514129 chr1:39547527 MACF1 0.87 7.87 0.58 1.51e-12 Fractional exhaled nitric oxide (childhood); TGCT cis rs7726839 0.540 rs72703095 chr5:601789 T/C cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs12711979 0.509 rs10200764 chr2:3827772 C/G cg17052675 chr2:3827356 NA -0.56 -13.37 -0.77 8.42e-26 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7267979 1.000 rs8125868 chr20:25324410 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs826838 0.967 rs7299170 chr12:38789536 G/A cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs8017423 0.904 rs11159963 chr14:90805358 C/T cg04374321 chr14:90722782 PSMC1 -0.73 -6.95 -0.53 1.82e-10 Mortality in heart failure; TGCT cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs5769707 0.554 rs10854876 chr22:50010570 T/C cg05373962 chr22:49881684 NA -0.3 -5.09 -0.42 1.31e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs11785400 1.000 rs6997670 chr8:143737915 G/A cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs7010267 0.596 rs4354338 chr8:120016060 A/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs7584330 0.554 rs6744807 chr2:238424684 A/G cg08992911 chr2:238395768 MLPH 0.66 4.73 0.39 5.91e-6 Prostate cancer; TGCT cis rs9486719 0.690 rs2092094 chr6:96844123 G/C cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs854765 0.583 rs8075965 chr17:17853180 A/T cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs1862618 0.671 rs2034244 chr5:56242774 T/C cg12311346 chr5:56204834 C5orf35 0.57 6.16 0.48 9.36e-9 Initial pursuit acceleration; TGCT cis rs12575480 0.901 rs6578977 chr11:2101804 C/T cg15541987 chr11:2077307 NA -0.39 -4.73 -0.39 6.13e-6 Pursuit maintenance gain; TGCT cis rs2721195 0.845 rs3816732 chr8:145724275 T/C cg17328964 chr8:145687451 CYHR1 -0.42 -5.71 -0.46 7.81e-8 Age at first birth; TGCT trans rs1974653 0.672 rs9606251 chr22:20092777 C/A cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs4252435 0.614 rs4987568 chr7:142590737 C/T cg09833174 chr7:143059591 FAM131B -0.95 -4.49 -0.37 1.58e-5 Cancer; TGCT cis rs950776 0.507 rs12912673 chr15:78810216 T/C cg06917634 chr15:78832804 PSMA4 0.97 9.62 0.65 1.05e-16 Sudden cardiac arrest; TGCT cis rs2730260 0.537 rs55864635 chr7:158859744 C/T cg02078164 chr7:157982224 PTPRN2 0.42 4.67 0.39 7.79e-6 Myopia (pathological); TGCT cis rs523522 0.923 rs2235217 chr12:120884328 C/T cg27279351 chr12:120934652 DYNLL1 0.74 6.4 0.5 2.95e-9 High light scatter reticulocyte count; TGCT cis rs9303401 0.659 rs17822908 chr17:56801778 T/C cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs7659604 0.676 rs6534323 chr4:122695888 G/A cg19748678 chr4:122722346 EXOSC9 0.87 9.36 0.64 4.56e-16 Type 2 diabetes; TGCT cis rs9972944 0.756 rs12600343 chr17:63764721 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs61990749 0.544 rs2544567 chr14:78181739 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.66 4.65 0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs1857353 1.000 rs116774684 chr1:75873384 C/T cg11838876 chr1:75668600 SLC44A5 -0.47 -4.62 -0.38 9.64e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs1552244 0.882 rs13084194 chr3:10031492 T/A cg00149659 chr3:10157352 C3orf10 0.79 4.96 0.41 2.27e-6 Alzheimer's disease; TGCT trans rs7618501 0.669 rs7634084 chr3:49949834 A/T cg21659725 chr3:3221576 CRBN 0.77 9.12 0.63 1.67e-15 Intelligence (multi-trait analysis); TGCT cis rs910316 0.967 rs175505 chr14:75529619 C/T cg08847533 chr14:75593920 NEK9 -0.92 -9.64 -0.65 9.33e-17 Height; TGCT cis rs4242434 0.597 rs4066629 chr8:22529073 A/C cg21658235 chr8:22456391 C8orf58 -0.46 -4.96 -0.41 2.31e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg01802117 chr1:53393560 SCP2 0.46 5.63 0.45 1.13e-7 Monocyte count; TGCT cis rs4563143 0.514 rs73029081 chr19:29295583 C/G cg04546413 chr19:29218101 NA 0.73 5.38 0.43 3.65e-7 Methadone dose in opioid dependence; TGCT cis rs826838 0.933 rs1906263 chr12:38653362 T/C cg26384229 chr12:38710491 ALG10B 1.05 10.25 0.68 3.18e-18 Heart rate; TGCT cis rs4891159 0.548 rs948646 chr18:74118168 G/A cg24786174 chr18:74118243 ZNF516 0.7 15.05 0.8 9.51e-30 Longevity; TGCT cis rs11677370 0.603 rs11675498 chr2:3850943 G/T cg17052675 chr2:3827356 NA -0.42 -7.13 -0.54 7.31e-11 Type 2 diabetes; TGCT cis rs2458413 1.000 rs2458413 chr8:105359432 C/T cg23108931 chr8:105342351 NA 0.36 6.01 0.48 1.91e-8 Paget's disease; TGCT cis rs9837602 0.507 rs793453 chr3:99529095 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.91 0.53 2.27e-10 Breast cancer; TGCT cis rs13191362 0.935 rs67673890 chr6:163107647 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.17 0.59 3.08e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28595532 1.000 rs115915387 chr4:119640854 C/T cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs478304 0.817 rs524475 chr11:65518065 T/A cg27068330 chr11:65405492 SIPA1 0.74 7.41 0.55 1.67e-11 Acne (severe); TGCT cis rs4746818 0.711 rs4745976 chr10:70845181 A/G cg11621586 chr10:70884670 VPS26A 1.05 7.01 0.53 1.34e-10 Left atrial antero-posterior diameter; TGCT cis rs12134245 0.776 rs12122066 chr1:92005140 C/T cg02896835 chr1:92012615 NA -0.28 -4.74 -0.39 5.75e-6 Breast cancer; TGCT cis rs6725041 0.547 rs4672645 chr2:213204955 C/T cg20637307 chr2:213403960 ERBB4 -0.53 -4.53 -0.38 1.37e-5 QT interval (ambient particulate matter interaction); TGCT cis rs6534347 0.512 rs6534354 chr4:123552125 T/A cg10583651 chr4:123538969 IL21 -0.31 -4.47 -0.37 1.73e-5 Type 1 diabetes; TGCT cis rs7954584 0.546 rs10840630 chr12:122352445 C/T cg22618164 chr12:122356400 WDR66 0.69 6.52 0.51 1.6e-9 Mean corpuscular volume; TGCT cis rs7937682 0.883 rs486038 chr11:111465963 A/C cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs6121246 0.909 rs6087778 chr20:30354142 G/A cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7843479 0.601 rs2306646 chr8:21846586 C/G cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.11e-12 Mean corpuscular volume; TGCT cis rs1799949 0.965 rs799908 chr17:41278916 A/G cg23758822 chr17:41437982 NA 0.68 6.78 0.52 4.4e-10 Menopause (age at onset); TGCT cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs2070488 0.965 rs2126534 chr3:38445165 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 9.73 0.66 5.78e-17 Electrocardiographic conduction measures; TGCT cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg19318889 chr4:1322082 MAEA 0.27 6.46 0.5 2.1e-9 Longevity; TGCT cis rs319204 1.000 rs319234 chr5:146241232 A/G cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs7432375 1.000 rs10935186 chr3:136346206 T/C cg12473912 chr3:136751656 NA 0.35 5.05 0.41 1.56e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs4499344 0.633 rs259258 chr19:33152523 A/G cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg22166914 chr1:53195759 ZYG11B -0.5 -9.4 -0.64 3.65e-16 Monocyte count; TGCT cis rs16958440 0.867 rs77599321 chr18:44689642 T/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT trans rs1005277 0.579 rs1780133 chr10:38499509 T/C cg17830980 chr10:43048298 ZNF37B -0.81 -10.14 -0.67 5.73e-18 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1670533 0.746 rs688008 chr4:1082829 T/C cg27284194 chr4:1044797 NA 0.69 5.93 0.47 2.78e-8 Recombination rate (females); TGCT cis rs1865760 0.827 rs9461227 chr6:25960815 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg05754148 chr16:3507555 NAT15 0.41 4.93 0.4 2.63e-6 Tuberculosis; TGCT cis rs1799949 0.965 rs7212284 chr17:41205941 A/G cg23758822 chr17:41437982 NA 0.7 6.75 0.52 5.19e-10 Menopause (age at onset); TGCT cis rs228769 0.543 rs170634 chr17:42175821 C/A cg19774624 chr17:42201019 HDAC5 0.7 6.71 0.52 6.31e-10 Bone mineral density (hip);Bone mineral density (spine); TGCT cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs11642862 1.000 rs11642466 chr16:30781942 A/G cg02466173 chr16:30829666 NA -0.39 -4.68 -0.39 7.24e-6 Tonsillectomy; TGCT cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg03517284 chr6:25882590 NA -0.68 -6.25 -0.49 6.06e-9 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.835 rs7936182 chr11:93665532 T/A cg26875233 chr11:93583750 C11orf90 -0.46 -5.74 -0.46 6.93e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg21644426 chr2:191273491 MFSD6 -0.6 -5.91 -0.47 3.12e-8 Pulse pressure; TGCT cis rs79057730 0.527 rs35316052 chr7:802954 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.41 0.44 3.16e-7 Initial pursuit acceleration; TGCT cis rs8067545 1.000 rs28807825 chr17:19942850 G/A cg13482628 chr17:19912719 NA 0.53 4.48 0.37 1.66e-5 Schizophrenia; TGCT cis rs1865760 0.865 rs10946800 chr6:25957773 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs8062405 0.789 rs1968751 chr16:28631759 T/C cg09754948 chr16:28834200 ATXN2L -0.59 -4.78 -0.39 4.82e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7249142 0.562 rs2314035 chr19:19284920 T/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.45 -4.5 -0.37 1.56e-5 IgG glycosylation; TGCT cis rs7246657 0.598 rs10405372 chr19:37668775 A/C cg24025825 chr19:37761650 NA -0.32 -5.02 -0.41 1.79e-6 Coronary artery calcification; TGCT cis rs17767294 0.708 rs9380018 chr6:27740646 A/G cg08851530 chr6:28072375 NA 0.93 4.57 0.38 1.19e-5 Parkinson's disease; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg02953382 chr22:24373134 LOC391322 -0.75 -7.44 -0.56 1.45e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12220238 1.000 rs2279648 chr10:75867193 G/T cg19889307 chr10:75911429 ADK;AP3M1 0.86 6.75 0.52 5.16e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs11931598 0.509 rs10937771 chr4:6940034 C/T cg02503808 chr4:7069936 GRPEL1 0.54 4.92 0.4 2.67e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs2404602 0.967 rs7167613 chr15:77041192 C/A cg22467129 chr15:76604101 ETFA -0.46 -5.04 -0.41 1.61e-6 Blood metabolite levels; TGCT cis rs56399783 0.901 rs79932907 chr7:2827901 C/G cg19731401 chr7:2775893 GNA12 0.37 5.15 0.42 1e-6 Childhood ear infection; TGCT cis rs9486719 1.000 rs11757063 chr6:96884886 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.69 -0.62 1.76e-14 Migraine;Coronary artery disease; TGCT cis rs7552404 0.727 rs1144336 chr1:76277421 C/A cg10523679 chr1:76189770 ACADM 0.74 7.2 0.54 5.04e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs854765 0.654 rs11078400 chr17:17757728 A/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.8 -0.4 4.56e-6 Total body bone mineral density; TGCT cis rs1348850 0.914 rs12693120 chr2:178283288 A/G cg22681709 chr2:178499509 PDE11A -0.35 -4.6 -0.38 1.03e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs739496 0.947 rs2339816 chr12:111912188 T/C cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.1e-7 Platelet count; TGCT cis rs7731657 0.575 rs12513465 chr5:130364503 A/G cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs881375 0.654 rs10760126 chr9:123662618 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.92e-7 Rheumatoid arthritis; TGCT cis rs11690935 0.731 rs10930491 chr2:172569824 A/G cg13550731 chr2:172543902 DYNC1I2 0.68 5.97 0.47 2.38e-8 Schizophrenia; TGCT cis rs7727544 0.716 rs11955347 chr5:131567924 G/A cg24060327 chr5:131705240 SLC22A5 -0.57 -5.23 -0.43 6.84e-7 Blood metabolite levels; TGCT cis rs7432375 0.901 rs1729951 chr3:136500733 T/G cg12473912 chr3:136751656 NA -0.35 -5.04 -0.41 1.62e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs10779751 1.000 rs11121703 chr1:11293792 G/T cg08854313 chr1:11322531 MTOR -0.99 -10.58 -0.69 4.78e-19 Body mass index; TGCT cis rs7172809 0.643 rs11855272 chr15:77840790 G/A cg22256960 chr15:77711686 NA -0.47 -4.73 -0.39 6.05e-6 Glucose homeostasis traits; TGCT trans rs4332037 0.901 rs7791899 chr7:1935988 T/C cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT cis rs1018836 0.631 rs2205158 chr8:91472515 C/T cg16814680 chr8:91681699 NA -0.77 -7.57 -0.56 7.42e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4478858 0.684 rs2062951 chr1:31762981 T/C cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs6725041 0.819 rs1996763 chr2:213082269 T/C cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT trans rs7824557 0.569 rs10106207 chr8:11015338 C/T cg06636001 chr8:8085503 FLJ10661 -0.8 -7.49 -0.56 1.13e-11 Retinal vascular caliber; TGCT cis rs769267 0.965 rs2074550 chr19:19387743 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg08859206 chr1:53392774 SCP2 0.39 5.8 0.46 5.07e-8 Monocyte count; TGCT cis rs7666738 0.830 rs13110498 chr4:98959150 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs981844 0.712 rs4571310 chr4:154746832 T/C cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs66573146 1.000 rs66519732 chr4:6990569 C/G cg05069807 chr4:6945702 TBC1D14 0.35 4.94 0.41 2.43e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs12134133 1.000 rs6540893 chr1:207435727 G/A cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs11098499 0.866 rs10518329 chr4:120401835 A/G cg09307838 chr4:120376055 NA 0.62 5.96 0.47 2.44e-8 Corneal astigmatism; TGCT cis rs12477438 0.798 rs6740267 chr2:99561867 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.02 -0.48 1.86e-8 Chronic sinus infection; TGCT cis rs1950500 0.545 rs724165 chr14:24806229 G/A cg22990158 chr14:24802150 ADCY4 -0.55 -4.84 -0.4 3.83e-6 Height; TGCT cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg09222892 chr1:25734099 RHCE -0.42 -7.1 -0.54 8.43e-11 Plateletcrit;Mean corpuscular volume; TGCT cis rs911263 0.603 rs60593979 chr14:68773298 C/G cg18825221 chr14:68749962 RAD51L1 0.22 4.44 0.37 1.97e-5 Primary biliary cholangitis; TGCT cis rs4595586 0.545 rs2388177 chr12:39364403 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs2629540 0.765 rs7097254 chr10:126512248 A/C cg08799069 chr10:126477246 METTL10 -0.28 -4.69 -0.39 7e-6 Cocaine dependence; TGCT cis rs6964587 0.839 rs10808086 chr7:91447515 T/C cg17063962 chr7:91808500 NA 0.82 8.31 0.6 1.43e-13 Breast cancer; TGCT cis rs473651 0.935 rs477041 chr2:239355995 C/G cg21699342 chr2:239360505 ASB1 -0.17 -4.74 -0.39 5.7e-6 Multiple system atrophy; TGCT cis rs4819052 1.000 rs733738 chr21:46666396 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.7 -5.5 -0.44 2.07e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1008375 0.800 rs10008598 chr4:17607323 T/C cg16339924 chr4:17578868 LAP3 0.74 5.92 0.47 3e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2710642 0.962 rs6545972 chr2:63084682 G/A cg17519650 chr2:63277830 OTX1 0.63 5.72 0.46 7.55e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg00814883 chr7:100076585 TSC22D4 0.92 9.69 0.66 7.12e-17 Platelet count; TGCT cis rs11083475 0.557 rs2368519 chr19:39259241 C/T cg17759274 chr19:39260954 NA 0.39 5.35 0.43 4.01e-7 Heart rate; TGCT cis rs1406084 0.636 rs7591244 chr2:154710717 C/T cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 0.967 rs686425 chr17:56776730 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs6598955 0.627 rs3924324 chr1:26616280 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT trans rs1005277 0.579 rs2474595 chr10:38426782 C/G cg17830980 chr10:43048298 ZNF37B 0.87 11.26 0.71 1.1e-20 Extrinsic epigenetic age acceleration; TGCT cis rs2216164 1.000 rs2216164 chr12:68534340 C/T cg17065850 chr12:67807625 NA -0.23 -4.44 -0.37 1.93e-5 Alopecia areata; TGCT cis rs13256369 0.760 rs7839473 chr8:8575836 C/T cg18904891 chr8:8559673 CLDN23 0.64 5.89 0.47 3.36e-8 Obesity-related traits; TGCT cis rs61990749 0.500 rs8011337 chr14:78272626 T/G cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs8141529 0.719 rs5762825 chr22:29223642 A/G cg02153584 chr22:29168773 CCDC117 0.67 5.69 0.45 8.82e-8 Lymphocyte counts; TGCT cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg03060546 chr3:49711283 APEH 0.53 5.14 0.42 1.05e-6 Menarche (age at onset); TGCT cis rs1005277 0.505 rs10827835 chr10:38150709 G/A cg25427524 chr10:38739819 LOC399744 0.37 7.47 0.56 1.24e-11 Extrinsic epigenetic age acceleration; TGCT cis rs587847 0.737 rs4924142 chr15:37621265 T/G cg00216138 chr15:37171175 LOC145845 0.31 4.57 0.38 1.15e-5 Intraocular pressure; TGCT cis rs2549003 0.966 rs2070730 chr5:131819800 G/A cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.92e-6 Asthma (sex interaction); TGCT cis rs13256369 1.000 rs4841017 chr8:8577093 A/G cg18904891 chr8:8559673 CLDN23 0.63 5.82 0.46 4.83e-8 Obesity-related traits; TGCT cis rs1843834 0.624 rs2396110 chr2:225560219 A/G cg22455342 chr2:225449267 CUL3 0.61 5.45 0.44 2.58e-7 IgE levels in asthmatics (D.p. specific); TGCT cis rs1519814 0.659 rs7387672 chr8:121024511 A/G cg22335954 chr8:121166405 COL14A1 -0.37 -4.73 -0.39 6.06e-6 Breast cancer; TGCT trans rs77457752 0.562 rs7874765 chr9:13899199 G/C cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.21e-10 Breast cancer; TGCT cis rs15676 0.783 rs6478851 chr9:131561110 G/A cg14578146 chr9:130637464 AK1 0.25 4.56 0.38 1.23e-5 Blood metabolite levels; TGCT cis rs829883 0.763 rs249843 chr12:98870987 G/A cg25150519 chr12:98850993 NA 0.64 7.84 0.58 1.8e-12 Colorectal adenoma (advanced); TGCT cis rs710216 0.957 rs841570 chr1:43435571 C/G cg03128534 chr1:43423976 SLC2A1 0.6 4.56 0.38 1.23e-5 Red cell distribution width; TGCT cis rs4077468 1.000 rs4077468 chr1:205914757 A/G cg07157834 chr1:205819609 PM20D1 -0.31 -4.43 -0.37 2.01e-5 Cystic fibrosis-related diabetes; TGCT cis rs114540395 1.000 rs114540395 chr10:103479062 C/T cg18276125 chr10:102749041 C10orf2 0.42 5.27 0.43 5.96e-7 Schizophrenia; TGCT cis rs6964587 1.000 rs10488512 chr7:91753579 C/T cg22709100 chr7:91322751 NA 0.28 4.52 0.38 1.45e-5 Breast cancer; TGCT cis rs735396 0.770 rs1169315 chr12:121443753 T/G cg15155738 chr12:121454335 C12orf43 0.55 4.81 0.4 4.38e-6 N-glycan levels; TGCT cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Vitiligo; TGCT cis rs736408 0.812 rs2270197 chr3:52824095 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.87 -0.4 3.34e-6 Bipolar disorder; TGCT cis rs46522 0.585 rs79049364 chr17:47014991 T/A cg27201301 chr17:47039149 GIP 0.26 4.58 0.38 1.12e-5 Coronary heart disease; TGCT cis rs832540 0.629 rs10940512 chr5:56082094 G/C cg24531977 chr5:56204891 C5orf35 -0.55 -5.42 -0.44 2.92e-7 Coronary artery disease; TGCT cis rs10875746 0.810 rs10875732 chr12:48442105 A/C cg20731937 chr12:48336164 NA 0.63 4.96 0.41 2.31e-6 Longevity (90 years and older); TGCT cis rs7647973 0.593 rs7620848 chr3:49828021 G/C cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.75 -0.39 5.61e-6 Menarche (age at onset); TGCT cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.87 8.62 0.61 2.69e-14 Intelligence (multi-trait analysis); TGCT cis rs4808199 0.948 rs11085261 chr19:19462606 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.48 0.44 2.24e-7 Nonalcoholic fatty liver disease; TGCT cis rs797680 0.786 rs9432465 chr1:93780591 G/A cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7647973 0.925 rs4955439 chr3:49245645 G/T cg07636037 chr3:49044803 WDR6 -0.63 -5.12 -0.42 1.11e-6 Menarche (age at onset); TGCT cis rs7666738 0.830 rs34244876 chr4:99031336 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6831352 1.000 rs1126673 chr4:100045616 C/T cg12011299 chr4:100065546 ADH4 0.41 5.01 0.41 1.81e-6 Alcohol dependence; TGCT cis rs9906944 0.707 rs11655950 chr17:47129121 C/T cg10950924 chr17:47092072 IGF2BP1 -0.34 -4.55 -0.38 1.26e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs4148883 0.689 rs1311621 chr4:100014018 T/C cg12011299 chr4:100065546 ADH4 0.38 5.72 0.46 7.41e-8 Alcohol dependence; TGCT cis rs10984561 0.881 rs58163718 chr9:122251146 A/C cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs1843834 0.505 rs3820763 chr2:225347270 A/G cg22455342 chr2:225449267 CUL3 -1.03 -10.95 -0.7 6.27e-20 IgE levels in asthmatics (D.p. specific); TGCT cis rs9549367 0.789 rs57747440 chr13:113894750 C/A cg00898013 chr13:113819073 PROZ -0.4 -4.98 -0.41 2.13e-6 Platelet distribution width; TGCT cis rs6598955 0.671 rs12086573 chr1:26574330 G/A cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs769267 1.000 rs12985655 chr19:19442434 G/A cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs7829975 0.511 rs1401390 chr8:8136410 C/T cg15462221 chr8:8086144 FLJ10661 -0.51 -4.44 -0.37 1.94e-5 Mood instability; TGCT cis rs138171347 1 rs138171347 chr17:5183203 AAAAT/A cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.71 0.39 6.58e-6 White blood cell count; TGCT cis rs7172809 0.573 rs13379686 chr15:77436191 T/C cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs7246657 0.943 rs3760825 chr19:37945601 C/T cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs3749237 0.964 rs2352975 chr3:49891885 T/C cg03060546 chr3:49711283 APEH 0.7 6.71 0.52 6.05e-10 Resting heart rate; TGCT cis rs910316 1.000 rs10142626 chr14:75555636 A/T cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs61990749 0.597 rs28534379 chr14:78172140 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.65 -0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs6089829 0.962 rs2314130 chr20:61665129 G/T cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs367615 0.918 rs10055528 chr5:108861129 G/T cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs4851266 0.966 rs1160545 chr2:100832269 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs1692580 0.682 rs12045693 chr1:2205581 A/C cg21194808 chr1:2205498 SKI -0.27 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT cis rs514406 0.861 rs505444 chr1:53251860 C/T cg08859206 chr1:53392774 SCP2 -0.38 -5.71 -0.46 8.07e-8 Monocyte count; TGCT cis rs765787 0.530 rs2413782 chr15:45538490 A/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs68170813 0.652 rs76924513 chr7:107205887 T/C cg02696742 chr7:106810147 HBP1 -0.59 -4.71 -0.39 6.61e-6 Coronary artery disease; TGCT cis rs875971 0.929 rs778682 chr7:65837934 A/G cg11764359 chr7:65958608 NA 0.62 5.57 0.45 1.51e-7 Aortic root size; TGCT cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg11301795 chr4:187892539 NA -0.3 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6570726 0.764 rs366673 chr6:145814628 T/A cg05347473 chr6:146136440 FBXO30 0.53 4.96 0.41 2.26e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2299587 0.637 rs7832527 chr8:17889343 C/A cg04898035 chr8:17640624 MTUS1 -0.22 -4.75 -0.39 5.59e-6 Economic and political preferences; TGCT cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg06634786 chr22:41940651 POLR3H 0.88 8.31 0.6 1.42e-13 Vitiligo; TGCT cis rs6866344 0.697 rs62392831 chr5:178134365 A/G cg03877680 chr5:178157825 ZNF354A 0.75 6.1 0.48 1.25e-8 Neutrophil percentage of white cells; TGCT trans rs208520 0.690 rs207077 chr6:66769855 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.0 -11.22 -0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs9926296 0.572 rs2376878 chr16:89885161 G/A cg27121462 chr16:89883253 FANCA 0.54 5.07 0.41 1.41e-6 Vitiligo; TGCT cis rs9640161 0.789 rs1464752 chr7:150021284 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 8.94e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs2521263 1.000 rs2651829 chr11:2308304 A/C cg10151367 chr11:2847642 KCNQ1 0.47 4.53 0.38 1.36e-5 Obesity-related traits; TGCT cis rs6087990 0.735 rs2424913 chr20:31374259 C/T cg13636640 chr20:31349939 DNMT3B 0.94 12.09 0.74 1.03e-22 Ulcerative colitis; TGCT cis rs7605378 0.688 rs769961 chr2:200712141 C/A cg17644776 chr2:200775616 C2orf69 0.34 6.79 0.52 4.07e-10 Osteoporosis; TGCT cis rs7674212 0.570 rs2711898 chr4:104063071 C/T cg16532752 chr4:104119610 CENPE -0.61 -5.64 -0.45 1.09e-7 Type 2 diabetes; TGCT cis rs73001065 0.901 rs73004926 chr19:19671266 C/T cg03709012 chr19:19516395 GATAD2A 1.03 5.03 0.41 1.65e-6 LDL cholesterol; TGCT cis rs1215050 0.791 rs700738 chr4:98907909 C/A cg17366294 chr4:99064904 C4orf37 -0.53 -5.69 -0.45 8.67e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9584850 0.874 rs7988959 chr13:99104004 T/C cg15168958 chr13:99100528 FARP1 -0.25 -4.51 -0.38 1.46e-5 Neuroticism; TGCT cis rs2013441 1.000 rs9900166 chr17:20192969 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs6089829 0.962 rs2314130 chr20:61665129 G/T cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT trans rs208520 0.661 rs4710566 chr6:66848538 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs4660261 0.545 rs803682 chr1:44362623 G/A cg12908607 chr1:44402522 ARTN -0.7 -8.79 -0.62 1.01e-14 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.31 -0.43 4.86e-7 Developmental language disorder (linguistic errors); TGCT cis rs73001065 0.818 rs73004975 chr19:19727152 A/G cg03709012 chr19:19516395 GATAD2A 1.06 5.2 0.42 8.02e-7 LDL cholesterol; TGCT trans rs7618501 0.633 rs2883057 chr3:49998282 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.4 0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs2742417 0.603 rs2531755 chr3:45772742 T/C cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7949030 0.626 rs11231154 chr11:62362293 A/G cg11742103 chr11:62369870 EML3;MTA2 0.61 8.75 0.62 1.29e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg11826961 chr17:38221639 THRA 0.59 6.65 0.51 8.31e-10 Gambling; TGCT cis rs6578985 1.000 rs116226565 chr11:2148166 C/G cg25742037 chr11:2171694 INS-IGF2;IGF2 0.24 4.66 0.39 8.07e-6 Femoral neck bone geometry and menarche (age at onset); TGCT cis rs950027 0.620 rs1145089 chr15:45652054 G/C cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs9926296 0.605 rs8047486 chr16:89854025 A/T cg21285383 chr16:89894308 SPIRE2 0.46 7.19 0.54 5.44e-11 Vitiligo; TGCT cis rs875971 0.830 rs28714531 chr7:65968237 G/A cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs912057 1.000 rs912057 chr6:6736931 C/T cg06612196 chr6:6737390 NA -0.38 -4.89 -0.4 3.02e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg05368731 chr17:41323189 NBR1 1.15 13.39 0.77 7.57e-26 Menopause (age at onset); TGCT cis rs3733585 0.638 rs7377625 chr4:9953099 T/C cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1218582 0.772 rs4845682 chr1:154877105 T/C cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs16957091 0.602 rs7178248 chr15:43199519 C/T cg17935677 chr15:44119062 WDR76 0.52 4.71 0.39 6.44e-6 MGMT methylation in smokers; TGCT cis rs2439831 0.681 rs1549525 chr15:43627855 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.04 8.86 0.62 7.03e-15 Lung cancer in ever smokers; TGCT cis rs921968 0.643 rs586374 chr2:219383003 A/C cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs858239 0.539 rs10254544 chr7:23220235 T/C cg05602783 chr7:23145260 KLHL7 -0.68 -5.31 -0.43 4.98e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1153858 1.000 rs1153858 chr15:45652703 A/G cg14582100 chr15:45693742 SPATA5L1 -0.49 -5.75 -0.46 6.63e-8 Homoarginine levels; TGCT cis rs11098499 0.644 rs10009566 chr4:120558608 A/G cg24670566 chr4:120433619 PDE5A 0.23 4.46 0.37 1.85e-5 Corneal astigmatism; TGCT cis rs6671200 1.000 rs71654418 chr1:95662658 G/T cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs10751667 0.600 rs10751665 chr11:941300 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs6684514 1.000 rs12117947 chr1:156244058 A/T cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs17270561 0.514 rs10946805 chr6:26077891 C/T cg16482183 chr6:26056742 HIST1H1C 1.0 7.6 0.56 6.14e-12 Iron status biomarkers; TGCT cis rs694739 0.628 rs10897487 chr11:64140704 C/T cg02228329 chr11:64053129 BAD;GPR137 0.7 6.8 0.52 4.02e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT trans rs916888 0.821 rs199505 chr17:44859410 A/G cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs597539 0.652 rs604524 chr11:68629929 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.27 0.6 1.72e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12510870 0.565 rs7687216 chr4:74411253 T/C cg05868023 chr4:75230803 EREG 0.53 4.63 0.38 9.08e-6 Iris color (b* coordinate); TGCT cis rs7662987 0.517 rs2602873 chr4:100039032 G/C cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs910316 0.935 rs175422 chr14:75627319 T/A cg08847533 chr14:75593920 NEK9 -0.92 -9.96 -0.67 1.6e-17 Height; TGCT cis rs7809950 0.593 rs62482503 chr7:106987988 A/G cg23024343 chr7:107201750 COG5 -0.43 -5.85 -0.47 4.12e-8 Coronary artery disease; TGCT cis rs1568889 0.712 rs4567438 chr11:28380051 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 5.5 0.44 2.1e-7 Bipolar disorder; TGCT cis rs597539 0.652 rs636049 chr11:68667198 A/C cg21862992 chr11:68658383 NA 0.46 6.57 0.51 1.25e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7586879 0.789 rs67221599 chr2:25131948 T/C cg01884057 chr2:25150051 NA 0.27 4.83 0.4 3.94e-6 Body mass index; TGCT cis rs28493229 0.786 rs73546894 chr19:41189203 C/T cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.49 0.44 2.18e-7 Kawasaki disease; TGCT cis rs4478858 0.698 rs11802155 chr1:31805012 T/C cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs79349575 0.749 rs58838744 chr17:46998902 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs9486719 1.000 rs2064947 chr6:97052754 C/T cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs3749237 1.000 rs4768 chr3:49758764 A/G cg10152585 chr3:50297680 NA 0.49 4.47 0.37 1.77e-5 Resting heart rate; TGCT cis rs68170813 0.559 rs6971774 chr7:106834139 A/G cg02696742 chr7:106810147 HBP1 -0.66 -5.58 -0.45 1.41e-7 Coronary artery disease; TGCT cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs782590 0.774 rs782637 chr2:55894247 T/C cg03859395 chr2:55845619 SMEK2 0.85 9.64 0.65 9.63e-17 Metabolic syndrome; TGCT cis rs5750830 0.649 rs5757664 chr22:39821536 A/G cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs9902453 1.000 rs62070312 chr17:28438877 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.6 0.51 1.07e-9 Coffee consumption (cups per day); TGCT cis rs752092 1.000 rs11247277 chr15:101784664 A/G cg25114630 chr15:101792522 CHSY1 0.56 5.36 0.43 3.88e-7 Corneal structure; TGCT cis rs8072100 0.713 rs11651643 chr17:45483229 A/G cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs10927875 0.541 rs761759 chr1:16342350 A/T cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs6809651 0.524 rs4686728 chr3:185795333 C/T cg00760338 chr3:185826511 ETV5 0.75 6.04 0.48 1.64e-8 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs6938 0.534 rs4886636 chr15:75196176 G/A cg09165964 chr15:75287851 SCAMP5 0.55 5.32 0.43 4.67e-7 Breast cancer; TGCT cis rs4680 0.737 rs6269 chr22:19949952 A/G cg22546130 chr22:19950026 COMT -0.35 -5.26 -0.43 6.21e-7 Blood metabolite levels; TGCT cis rs1045714 0.895 rs73043182 chr7:2646005 C/T cg17215154 chr7:2644645 IQCE 0.28 4.92 0.4 2.75e-6 Urate levels in lean individuals; TGCT cis rs362296 0.511 rs2857861 chr4:3323767 C/T cg06533319 chr4:3265114 C4orf44 -0.21 -4.63 -0.38 9.27e-6 Parental longevity (mother's age at death); TGCT cis rs10256972 0.647 rs10233430 chr7:1051664 T/C cg16145915 chr7:1198662 ZFAND2A -0.47 -5.47 -0.44 2.35e-7 Longevity;Endometriosis; TGCT cis rs41271951 0.512 rs12074309 chr1:151087827 T/C cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs617791 0.678 rs551659 chr11:65749645 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.69 6.77 0.52 4.5e-10 Breast cancer; TGCT cis rs2404602 0.692 rs58973160 chr15:77000342 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.19e-6 Blood metabolite levels; TGCT cis rs1371867 0.839 rs1788186 chr8:101335686 T/C cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs7246657 0.943 rs3745765 chr19:37854235 G/T cg03233940 chr19:37894644 NA -0.34 -4.49 -0.37 1.59e-5 Coronary artery calcification; TGCT cis rs11190604 1.000 rs3750627 chr10:102275642 G/T cg16342193 chr10:102329863 NA -0.42 -5.45 -0.44 2.6e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9549367 0.789 rs9549718 chr13:113909822 A/G cg00898013 chr13:113819073 PROZ -0.41 -5.09 -0.42 1.31e-6 Platelet distribution width; TGCT cis rs17539620 0.534 rs7768635 chr6:154827861 C/T cg20019720 chr6:154832845 CNKSR3 0.46 4.46 0.37 1.79e-5 Lipoprotein (a) levels; TGCT cis rs9902453 0.967 rs17825877 chr17:28515188 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.3 0.49 4.72e-9 Coffee consumption (cups per day); TGCT cis rs910316 0.699 rs175039 chr14:75468950 G/C cg08847533 chr14:75593920 NEK9 -0.84 -8.91 -0.62 5.45e-15 Height; TGCT cis rs950169 0.887 rs71395453 chr15:85113490 G/C cg11189052 chr15:85197271 WDR73 0.77 6.44 0.5 2.34e-9 Schizophrenia; TGCT cis rs7582180 0.764 rs11683121 chr2:100920705 C/T cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.45e-6 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs1932275 chr6:8442333 T/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs350251 0.837 rs1641850 chr16:12188433 C/G cg01574788 chr16:12184133 SNX29 0.36 4.74 0.39 5.87e-6 Intelligence (multi-trait analysis); TGCT cis rs6671200 1.000 rs35179427 chr1:95670888 G/A cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT trans rs4332037 1.000 rs10240470 chr7:1949971 G/T cg25206134 chr2:45395956 NA -1.12 -9.49 -0.65 2.13e-16 Bipolar disorder; TGCT cis rs4449834 0.851 rs6982898 chr8:61704083 C/T cg12485212 chr8:61565947 NA -0.59 -4.61 -0.38 9.88e-6 Sum eosinophil basophil counts; TGCT cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg13695892 chr22:41940480 POLR3H -0.9 -9.01 -0.63 3.17e-15 Vitiligo; TGCT cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg02187348 chr16:89574699 SPG7 0.62 6.66 0.51 7.91e-10 Multiple myeloma (IgH translocation); TGCT cis rs7103648 0.966 rs1534576 chr11:47419663 A/C cg20307385 chr11:47447363 PSMC3 -1.04 -12.01 -0.73 1.65e-22 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs736408 0.522 rs998909 chr3:52805093 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.66 6.16 0.48 9.18e-9 Bipolar disorder; TGCT cis rs7226408 0.857 rs72885278 chr18:34441154 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.74 0.39 5.85e-6 Obesity-related traits; TGCT cis rs875971 0.651 rs2420596 chr7:65915983 T/C cg11764359 chr7:65958608 NA 0.58 5.33 0.43 4.47e-7 Aortic root size; TGCT cis rs782590 1.000 rs782590 chr2:55843413 C/T cg18811423 chr2:55921094 PNPT1 0.65 6.77 0.52 4.64e-10 Metabolic syndrome; TGCT cis rs910316 0.967 rs11159116 chr14:75550584 G/T cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT cis rs13191362 1.000 rs34773528 chr6:163088796 G/C cg06582575 chr6:163149167 PACRG;PARK2 0.98 7.66 0.57 4.67e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9647570 0.668 rs11134473 chr5:167270818 G/A cg11091196 chr5:167285540 ODZ2 0.32 4.71 0.39 6.62e-6 Menarche (age at onset); TGCT cis rs2288073 0.965 rs10469924 chr2:24416230 G/A cg02683114 chr2:24398427 C2orf84 -0.25 -5.67 -0.45 9.72e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs9398235 1.000 rs9398235 chr6:110732116 A/G cg00083206 chr6:110721305 DDO -0.45 -4.72 -0.39 6.22e-6 Systemic lupus erythematosus; TGCT trans rs12339966 0.581 rs56080329 chr9:11330372 A/G cg03488587 chr11:64876988 C11orf2 0.32 7.03 0.53 1.19e-10 Systolic blood pressure; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg22166914 chr1:53195759 ZYG11B 0.37 6.34 0.5 3.81e-9 Monocyte count; TGCT cis rs10875595 0.691 rs1076361 chr5:140674609 C/T cg20560182 chr5:140700478 TAF7 -0.65 -4.68 -0.39 7.3e-6 Pulmonary function decline; TGCT cis rs9910055 0.659 rs6503488 chr17:42246158 T/G cg13607699 chr17:42295918 UBTF 0.59 5.46 0.44 2.53e-7 Total body bone mineral density; TGCT cis rs362272 0.505 rs60208975 chr4:3364530 A/G cg22655196 chr4:3374909 RGS12 0.24 4.91 0.4 2.8e-6 Serum sulfate level; TGCT cis rs6500602 0.563 rs917305 chr16:4440593 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.38 5.56 0.45 1.55e-7 Schizophrenia; TGCT cis rs595982 0.559 rs117227130 chr19:49367959 A/G cg21252483 chr19:49399788 TULP2 -0.42 -6.39 -0.5 3.02e-9 Red cell distribution width; TGCT cis rs7267979 1.000 rs2500443 chr20:25331442 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11779988 0.545 rs208763 chr8:17806482 G/A cg01800426 chr8:17659068 MTUS1 -0.64 -4.99 -0.41 2.02e-6 Breast cancer; TGCT cis rs10992471 0.528 rs1924243 chr9:95224847 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2075371 0.933 rs432336 chr7:133949064 A/G cg11752832 chr7:134001865 SLC35B4 0.68 5.88 0.47 3.48e-8 Mean platelet volume; TGCT cis rs910316 1.000 rs12589376 chr14:75561152 C/T cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs3617 0.573 rs13072537 chr3:52896032 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.61 0.38 9.76e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs17401966 0.540 rs10864452 chr1:10395683 G/T cg19773385 chr1:10388646 KIF1B -0.21 -5.07 -0.41 1.44e-6 Hepatocellular carcinoma; TGCT cis rs1372520 0.684 rs2619355 chr4:90748374 A/C cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs6558530 0.692 rs7818406 chr8:1701250 C/T cg09410841 chr8:1729607 CLN8 0.72 6.49 0.5 1.87e-9 Systolic blood pressure; TGCT cis rs13118159 0.801 rs10024996 chr4:1328297 G/A cg13395646 chr4:1353034 KIAA1530 -0.39 -4.82 -0.4 4.08e-6 Longevity; TGCT cis rs10875746 0.669 rs10875772 chr12:48609553 C/T cg20731937 chr12:48336164 NA 0.65 4.96 0.41 2.31e-6 Longevity (90 years and older); TGCT cis rs13256369 0.802 rs12680019 chr8:8561698 A/G cg18904891 chr8:8559673 CLDN23 0.57 5.27 0.43 5.87e-7 Obesity-related traits; TGCT cis rs1008375 0.646 rs4235387 chr4:17569327 T/G cg10189774 chr4:17578691 LAP3 0.65 5.5 0.44 2.1e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs933688 1.000 rs6865495 chr5:90746424 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 9.32 0.64 5.66e-16 Smoking behavior; TGCT cis rs9972944 0.702 rs987930 chr17:63765862 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs57920188 0.585 rs6703106 chr1:4068337 C/T cg20703997 chr1:4087676 NA 0.48 5.91 0.47 3.14e-8 Interleukin-17 levels; TGCT cis rs11673344 0.523 rs7260488 chr19:37549785 G/A cg08039142 chr19:36980659 ZNF566 0.5 4.64 0.38 8.58e-6 Obesity-related traits; TGCT cis rs12497850 0.931 rs10780033 chr3:48891275 T/C cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs9400467 0.537 rs12214886 chr6:111500081 C/T cg15721981 chr6:111408429 SLC16A10 0.7 4.48 0.37 1.66e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg22166914 chr1:53195759 ZYG11B 0.3 4.87 0.4 3.29e-6 Monocyte count; TGCT cis rs112591243 0.614 rs78654337 chr21:47824372 A/G cg10657630 chr21:48055338 PRMT2 1.06 5.27 0.43 5.79e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs858239 0.669 rs1618339 chr7:23229774 T/C cg05602783 chr7:23145260 KLHL7 -0.55 -4.54 -0.38 1.32e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs4455778 0.538 rs7786675 chr7:49123150 C/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs4252435 0.614 rs8176036 chr7:142640596 T/G cg09833174 chr7:143059591 FAM131B -1.02 -4.65 -0.39 8.26e-6 Cancer; TGCT cis rs950169 0.922 rs4842941 chr15:84831312 G/C cg11189052 chr15:85197271 WDR73 -0.81 -6.5 -0.5 1.78e-9 Schizophrenia; TGCT cis rs6089829 0.962 rs4809455 chr20:61660781 G/C cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7552404 0.889 rs2211080 chr1:76243438 G/A cg10523679 chr1:76189770 ACADM 0.77 7.43 0.56 1.52e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg13397359 chr6:42928475 GNMT 0.73 6.81 0.52 3.7e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs921968 0.541 rs3731867 chr2:219472734 G/A cg02176678 chr2:219576539 TTLL4 -0.49 -6.85 -0.52 3.03e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs597480 0.853 rs475380 chr11:85446708 T/A cg11817631 chr11:85522609 SYTL2 -0.48 -4.81 -0.4 4.23e-6 Drug-induced liver injury (nonsteroidal anti-inflammatory drugs); TGCT cis rs10851411 0.908 rs10851410 chr15:42844788 A/G cg23803468 chr15:43513504 EPB42 0.27 5.16 0.42 9.47e-7 Glucose homeostasis traits; TGCT cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs2070488 0.699 rs6599205 chr3:38529440 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.69 6.13 0.48 1.09e-8 Electrocardiographic conduction measures; TGCT cis rs2836974 0.897 rs13052882 chr21:40555351 G/C cg17971929 chr21:40555470 PSMG1 0.97 8.85 0.62 7.27e-15 Cognitive function; TGCT cis rs4824093 0.610 rs4141437 chr22:50243719 C/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.45 -4.65 -0.39 8.43e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs4786125 0.512 rs55694271 chr16:6930378 G/A cg03623568 chr16:6915990 A2BP1 -0.41 -5.71 -0.46 7.91e-8 Heart rate variability traits (SDNN); TGCT cis rs669446 0.531 rs673485 chr1:44087496 C/T cg12908607 chr1:44402522 ARTN -0.44 -4.58 -0.38 1.11e-5 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs3087591 0.879 rs59015798 chr17:29580882 G/A cg24425628 chr17:29625626 OMG;NF1 -0.43 -6.43 -0.5 2.53e-9 Hip circumference; TGCT trans rs1814175 0.817 rs10769648 chr11:50013992 T/C cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs6582630 0.537 rs11520294 chr12:38402705 C/A cg26384229 chr12:38710491 ALG10B 0.84 7.42 0.55 1.62e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs35306767 0.903 rs35637113 chr10:874149 G/C cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs13242816 1.000 rs17138747 chr7:116132670 G/A cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT cis rs7312933 0.524 rs11181465 chr12:42765098 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.14 0.42 1.03e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9487051 0.714 rs7757347 chr6:109633815 G/A cg01475377 chr6:109611718 NA -0.31 -4.73 -0.39 6.12e-6 Reticulocyte fraction of red cells; TGCT cis rs6669384 0.737 rs12145290 chr1:208037821 C/T cg22525895 chr1:207977042 MIR29B2 -0.4 -5.53 -0.44 1.8e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs8062405 1.000 rs9972693 chr16:28859802 A/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7552404 0.961 rs17587071 chr1:76225083 A/C cg03433033 chr1:76189801 ACADM 0.84 9.57 0.65 1.38e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2795502 0.873 rs1891324 chr10:43399581 A/G cg20628663 chr10:43360327 NA 0.36 5.45 0.44 2.66e-7 Blood protein levels; TGCT cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg05368731 chr17:41323189 NBR1 1.16 13.76 0.78 1.03e-26 Menopause (age at onset); TGCT cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg13695892 chr22:41940480 POLR3H -0.91 -8.81 -0.62 9.48e-15 Vitiligo; TGCT cis rs6500602 0.893 rs4785962 chr16:4484328 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.29 4.9 0.4 2.99e-6 Schizophrenia; TGCT cis rs9443645 0.901 rs9341754 chr6:79584973 A/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs7927771 0.832 rs935914 chr11:47387599 C/T cg21462715 chr11:47870315 NUP160 -0.56 -4.63 -0.38 9.16e-6 Subjective well-being; TGCT cis rs832540 0.656 rs832573 chr5:56159578 T/C cg24531977 chr5:56204891 C5orf35 -0.51 -4.94 -0.41 2.43e-6 Coronary artery disease; TGCT cis rs1153858 1.000 rs1719247 chr15:45620985 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.82 0.46 4.77e-8 Homoarginine levels; TGCT cis rs2688608 0.617 rs6480709 chr10:75479125 T/C cg04320760 chr10:75533139 FUT11 -0.39 -6.01 -0.48 1.89e-8 Inflammatory bowel disease; TGCT cis rs17125944 0.505 rs75296244 chr14:53233218 G/A cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs6459788 0.585 rs6950818 chr7:157235364 C/G cg06271696 chr7:157225062 NA -0.37 -7.01 -0.53 1.34e-10 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs11190604 0.767 rs11190509 chr10:102156208 G/A cg23241863 chr10:102295624 HIF1AN 0.61 4.58 0.38 1.12e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6671200 0.607 rs3767313 chr1:95712797 G/A cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs2016266 0.784 rs7308162 chr12:53654956 G/A cg16917193 chr12:54089295 NA 0.67 4.89 0.4 3.05e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg04944784 chr2:26401820 FAM59B -0.81 -6.87 -0.52 2.82e-10 Gut microbiome composition (summer); TGCT cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg17971929 chr21:40555470 PSMG1 -0.52 -4.71 -0.39 6.45e-6 Menarche (age at onset); TGCT cis rs6088590 1.000 rs6119516 chr20:33328024 C/T cg24642439 chr20:33292090 TP53INP2 0.69 6.02 0.48 1.85e-8 Coronary artery disease; TGCT cis rs59107033 0.607 rs6771700 chr3:123117488 C/T cg04890266 chr3:123102914 ADCY5 -0.37 -5.12 -0.42 1.13e-6 Lymphocyte counts; TGCT cis rs6570726 0.791 rs11155435 chr6:145938545 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.69 0.66 7.3e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg16049864 chr8:95962084 TP53INP1 -0.73 -10.22 -0.68 3.63e-18 Type 2 diabetes; TGCT cis rs35883536 0.647 rs2783693 chr1:101045040 C/T cg06223162 chr1:101003688 GPR88 0.42 7.84 0.58 1.77e-12 Monocyte count; TGCT cis rs57590327 0.679 rs17019030 chr3:81552062 C/T cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs713587 0.563 rs10865315 chr2:25100738 C/A cg01884057 chr2:25150051 NA 0.31 5.82 0.46 4.63e-8 Body mass index in non-asthmatics; TGCT cis rs968567 0.539 rs174560 chr11:61581764 T/C cg19610905 chr11:61596333 FADS2 -1.07 -11.78 -0.73 5.92e-22 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs4689388 0.926 rs3889821 chr4:6282596 C/T cg25554036 chr4:6271136 WFS1 0.55 8.09 0.59 4.65e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2742417 1.000 rs2742423 chr3:45733430 A/G cg04837898 chr3:45731254 SACM1L -0.56 -5.92 -0.47 2.89e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9362426 0.895 rs242292 chr6:88078074 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.07 0.41 1.43e-6 Depressive episodes in bipolar disorder; TGCT cis rs12950390 0.893 rs12325760 chr17:45840886 C/T cg06532163 chr17:45867833 NA 0.34 5.31 0.43 4.82e-7 IgG glycosylation; TGCT cis rs1997103 0.906 rs4618644 chr7:55402037 T/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg25703541 chr22:24373054 LOC391322 -0.78 -6.8 -0.52 3.94e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1555895 0.576 rs12413763 chr10:849454 A/G cg02193355 chr10:851439 NA 0.22 4.96 0.41 2.28e-6 Survival in rectal cancer; TGCT cis rs17767294 0.708 rs72848763 chr6:27902488 A/G cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs7666738 0.546 rs10007424 chr4:98885450 C/T cg05340658 chr4:99064831 C4orf37 0.58 6.18 0.49 8.3e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs35000415 0.688 rs13222044 chr7:128716525 C/T cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs2786098 0.577 rs10922304 chr1:197820945 C/A cg00114966 chr1:197893920 LHX9 0.38 4.62 0.38 9.45e-6 Asthma; TGCT cis rs4727027 0.870 rs1568945 chr7:148874112 T/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.77 0.39 5.16e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7824557 0.737 rs2293855 chr8:11177410 G/A cg21775007 chr8:11205619 TDH 0.52 4.97 0.41 2.22e-6 Retinal vascular caliber; TGCT cis rs2836974 0.666 rs4624474 chr21:40686327 T/C cg06238570 chr21:40685208 BRWD1 -0.84 -9.31 -0.64 6.01e-16 Cognitive function; TGCT cis rs950169 0.840 rs4842854 chr15:84942339 T/G cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs6977660 0.507 rs72591449 chr7:19775443 T/C cg07541023 chr7:19748670 TWISTNB 1.01 6.55 0.51 1.39e-9 Thyroid stimulating hormone; TGCT cis rs2014572 0.967 rs7248000 chr19:57762139 C/T cg24459738 chr19:57751996 ZNF805 -0.58 -5.69 -0.46 8.5e-8 Hyperactive-impulsive symptoms; TGCT cis rs9322193 0.884 rs62439836 chr6:149990309 A/G cg13206674 chr6:150067644 NUP43 0.53 4.56 0.38 1.23e-5 Lung cancer; TGCT cis rs2153535 0.580 rs2327057 chr6:8443319 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs7659604 1.000 rs28640980 chr4:122664284 T/C cg19748678 chr4:122722346 EXOSC9 0.57 5.54 0.45 1.69e-7 Type 2 diabetes; TGCT cis rs7267979 1.000 rs2258879 chr20:25279213 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7552404 0.727 rs7521344 chr1:76318325 C/T cg22875332 chr1:76189707 ACADM -0.58 -6.24 -0.49 6.18e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9972944 0.756 rs7220733 chr17:63764890 A/T cg07283582 chr17:63770753 CCDC46 -0.23 -4.89 -0.4 3.03e-6 Total body bone mineral density; TGCT cis rs13191362 0.810 rs13209784 chr6:162961274 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.17e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9300255 0.602 rs1716164 chr12:123663660 G/A cg00376283 chr12:123451042 ABCB9 0.72 5.61 0.45 1.27e-7 Neutrophil percentage of white cells; TGCT cis rs1005277 0.557 rs1854563 chr10:38434961 G/A cg13531842 chr10:38383804 ZNF37A -0.39 -4.64 -0.38 8.78e-6 Extrinsic epigenetic age acceleration; TGCT cis rs9611565 0.525 rs1883827 chr22:41703579 A/G cg13695892 chr22:41940480 POLR3H -0.64 -6.03 -0.48 1.78e-8 Vitiligo; TGCT cis rs1008375 0.932 rs9884565 chr4:17655096 A/G cg10189774 chr4:17578691 LAP3 0.58 4.99 0.41 1.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg24250549 chr1:154909240 PMVK 0.66 6.5 0.5 1.73e-9 Prostate cancer; TGCT cis rs427394 0.659 rs187295 chr5:6734326 C/T cg10857441 chr5:6722123 POLS -0.27 -5.7 -0.46 8.2e-8 Menopause (age at onset); TGCT cis rs11578119 0.933 rs10919417 chr1:170442454 A/C cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs72615157 0.645 rs11771660 chr7:99851269 T/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.61 4.72 0.39 6.31e-6 Lung function (FEV1/FVC); TGCT cis rs669446 0.561 rs641365 chr1:44083507 A/G cg12908607 chr1:44402522 ARTN -0.57 -6.2 -0.49 7.8e-9 Amyotrophic lateral sclerosis (age of onset); TGCT trans rs11722228 0.508 rs61335146 chr4:10130793 G/C cg26043149 chr18:55253948 FECH 1.24 14.45 0.79 2.36e-28 Gout;Urate levels;Serum uric acid levels; TGCT cis rs11249608 0.548 rs7733072 chr5:178456007 A/G cg23951258 chr5:178450506 ZNF879 0.44 4.54 0.38 1.32e-5 Pubertal anthropometrics; TGCT cis rs9929218 0.551 rs9888942 chr16:68727572 A/G cg01251360 chr16:68772225 CDH1 -0.28 -5.31 -0.43 4.95e-7 Colorectal cancer; TGCT cis rs9831754 0.906 rs9869812 chr3:78385679 G/A cg06138941 chr3:78371609 NA -0.49 -5.4 -0.44 3.25e-7 Calcium levels; TGCT cis rs11098499 0.954 rs17009122 chr4:120362403 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg16497277 chr3:49208875 KLHDC8B 0.53 5.13 0.42 1.09e-6 Menarche (age at onset); TGCT cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg17264618 chr3:40429014 ENTPD3 -0.33 -4.85 -0.4 3.66e-6 Renal cell carcinoma; TGCT cis rs2017387 0.572 rs157548 chr19:50540237 A/G cg19230443 chr19:49950584 PIH1D1 -0.29 -4.69 -0.39 7.22e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg06238570 chr21:40685208 BRWD1 0.72 6.58 0.51 1.16e-9 Cognitive function; TGCT cis rs1784581 0.588 rs9355971 chr6:162421242 A/G cg17173639 chr6:162384350 PARK2 0.39 6.5 0.5 1.73e-9 Itch intensity from mosquito bite; TGCT cis rs6138458 1.000 rs227629 chr20:24913551 G/T cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs7819412 0.745 rs28464654 chr8:11080665 T/A cg21775007 chr8:11205619 TDH -0.56 -5.15 -0.42 9.93e-7 Triglycerides; TGCT cis rs7666738 0.830 rs28810677 chr4:99043193 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs804292 1.000 rs804292 chr8:11643915 C/T cg26752888 chr8:11627280 NEIL2 -1.03 -12.0 -0.73 1.72e-22 Alcohol dependence;Nicotine use; TGCT cis rs4450131 1.000 rs10901799 chr10:126348274 A/G cg20435097 chr10:126320824 FAM53B -0.18 -4.59 -0.38 1.09e-5 White blood cell count (basophil); TGCT cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg03517284 chr6:25882590 NA 0.89 9.12 0.63 1.72e-15 Blood metabolite levels; TGCT cis rs40363 1.000 rs1690443 chr16:3517787 C/G cg00484396 chr16:3507460 NAT15 0.42 5.05 0.41 1.51e-6 Tuberculosis; TGCT cis rs227584 0.501 rs62078931 chr17:42198059 A/C cg19774624 chr17:42201019 HDAC5 0.6 6.31 0.49 4.5e-9 Bone mineral density (hip);Bone mineral density; TGCT cis rs2050392 0.590 rs685319 chr10:30719331 G/A cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs6722750 0.967 rs17754672 chr2:64400608 A/G cg22352474 chr2:64371530 PELI1 -0.61 -5.34 -0.43 4.19e-7 Neuroticism; TGCT cis rs910316 1.000 rs12435391 chr14:75601737 A/G cg23033748 chr14:75592666 NEK9 0.28 4.81 0.4 4.24e-6 Height; TGCT cis rs11148252 0.574 rs73186430 chr13:53232891 T/C cg00495681 chr13:53174319 NA 0.72 7.5 0.56 1.07e-11 Lewy body disease; TGCT cis rs1218582 0.804 rs4845678 chr1:154853295 A/G cg24250549 chr1:154909240 PMVK 0.66 6.56 0.51 1.31e-9 Prostate cancer; TGCT cis rs4819052 0.918 rs2330013 chr21:46658662 G/T cg06618935 chr21:46677482 NA -0.37 -5.01 -0.41 1.86e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2535633 0.661 rs4515041 chr3:52996032 T/A cg10802521 chr3:52805072 NEK4 0.56 6.02 0.48 1.86e-8 Body mass index; TGCT cis rs911555 0.755 rs11620897 chr14:103944861 T/G cg12935359 chr14:103987150 CKB -0.33 -4.59 -0.38 1.07e-5 Intelligence (multi-trait analysis); TGCT cis rs9905704 0.647 rs2036730 chr17:57038282 A/G cg12560992 chr17:57184187 TRIM37 0.58 5.05 0.41 1.52e-6 Testicular germ cell tumor; TGCT cis rs2354432 0.607 rs7537279 chr1:146673642 A/G cg25205988 chr1:146714368 CHD1L 1.33 6.35 0.5 3.68e-9 Mitochondrial DNA levels; TGCT cis rs826838 1.000 rs10880914 chr12:38720543 C/T cg13010199 chr12:38710504 ALG10B 0.83 6.83 0.52 3.43e-10 Heart rate; TGCT cis rs9486715 0.867 rs4240553 chr6:96965324 T/C cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs4819052 0.851 rs2838848 chr21:46671017 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2692947 0.726 rs13019188 chr2:96774199 A/G cg22654517 chr2:96458247 NA -0.22 -4.83 -0.4 3.96e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9303401 0.614 rs2333409 chr17:57139134 G/A cg25039879 chr17:56429692 SUPT4H1 0.54 4.84 0.4 3.85e-6 Cognitive test performance; TGCT cis rs2997447 0.761 rs56299762 chr1:26441638 G/A cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs7095607 0.785 rs7081820 chr10:69914009 C/T cg18986048 chr10:69913749 MYPN 0.43 4.87 0.4 3.29e-6 Lung function (FVC); TGCT cis rs5758659 0.714 rs133373 chr22:42465788 G/A cg15557168 chr22:42548783 NA -0.18 -4.63 -0.38 9.08e-6 Cognitive function; TGCT cis rs709400 1.000 rs8018979 chr14:104109087 G/A cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT trans rs1814175 0.740 rs10839439 chr11:49918240 C/T cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs8031584 0.958 rs11637469 chr15:31238783 T/C cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.29e-6 Huntington's disease progression; TGCT cis rs3096299 0.869 rs748941 chr16:89440754 T/A cg05504729 chr16:89399490 ANKRD11 -0.22 -4.44 -0.37 2e-5 Multiple myeloma (IgH translocation); TGCT cis rs11190604 1.000 rs1054399 chr10:102312565 C/T cg23241863 chr10:102295624 HIF1AN 0.68 5.13 0.42 1.08e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9858542 0.953 rs11715915 chr3:49455330 A/G cg03060546 chr3:49711283 APEH 0.59 5.3 0.43 5.08e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 8.11 0.59 4.07e-13 Platelet count; TGCT cis rs7100689 0.577 rs2282367 chr10:82040346 A/G cg01528321 chr10:82214614 TSPAN14 0.69 6.64 0.51 8.59e-10 Post bronchodilator FEV1; TGCT cis rs9457247 0.967 rs1590257 chr6:167377782 G/T cg25258033 chr6:167368657 RNASET2 -0.18 -4.48 -0.37 1.64e-5 Crohn's disease; TGCT cis rs236907 0.859 rs2294718 chr1:171750854 C/G cg20598894 chr1:171756153 METTL13 -0.2 -4.54 -0.38 1.31e-5 Mean platelet volume; TGCT cis rs28595532 0.920 rs17259173 chr4:119777232 T/C cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs10795061 0.576 rs12219804 chr10:3710626 C/T cg13668419 chr10:3197757 PITRM1 -0.18 -4.72 -0.39 6.14e-6 Subjective well-being; TGCT cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs3733585 0.579 rs4235353 chr4:10122934 C/T cg11266682 chr4:10021025 SLC2A9 -0.56 -6.45 -0.5 2.28e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9674544 0.757 rs9896443 chr17:47125982 A/G cg10950924 chr17:47092072 IGF2BP1 -0.31 -4.51 -0.38 1.48e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs7552404 0.727 rs61770533 chr1:76306490 C/G cg22875332 chr1:76189707 ACADM 0.63 6.74 0.52 5.33e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6570726 0.935 rs390252 chr6:145856896 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7264396 0.676 rs6060727 chr20:34556000 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs6671200 0.920 rs11165339 chr1:95674064 T/C cg03123541 chr1:95699097 RWDD3 -0.87 -6.17 -0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg24846343 chr22:24311635 DDTL 0.23 5.79 0.46 5.54e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2463822 1.000 rs2513076 chr11:62103711 A/G cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs11779988 0.543 rs410445 chr8:17882304 C/T cg01800426 chr8:17659068 MTUS1 -0.69 -5.59 -0.45 1.35e-7 Breast cancer; TGCT cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg20607798 chr8:58055168 NA -0.48 -4.78 -0.39 4.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs9372498 0.536 rs62422220 chr6:118923731 G/A cg07617317 chr6:118971624 C6orf204 0.49 5.22 0.42 7.37e-7 Diastolic blood pressure; TGCT cis rs61612642 0.537 rs6915565 chr6:42192582 G/A cg01092361 chr6:42185687 MRPS10 0.98 7.15 0.54 6.56e-11 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs7845219 0.544 rs7001535 chr8:95921090 C/G cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs10493773 0.609 rs11161664 chr1:86185379 C/T cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs2486012 0.737 rs4660749 chr1:44250301 T/G cg12908607 chr1:44402522 ARTN -0.71 -5.61 -0.45 1.26e-7 Intelligence (multi-trait analysis); TGCT cis rs17102423 0.594 rs1998688 chr14:65562306 C/G cg11161011 chr14:65562177 MAX 0.47 6.56 0.51 1.32e-9 Obesity-related traits; TGCT cis rs4944092 0.855 rs608747 chr11:75916477 A/G cg04588336 chr11:75916460 WNT11 -0.43 -5.89 -0.47 3.41e-8 PR interval; TGCT cis rs10031466 1.000 rs2279550 chr4:189012728 G/C cg14506195 chr4:188913931 NA -0.25 -4.78 -0.39 4.86e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs10782582 0.609 rs11588643 chr1:76255613 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs6952808 0.782 rs4236271 chr7:1881369 C/T cg22963979 chr7:1858916 MAD1L1 -0.34 -5.14 -0.42 1.05e-6 Bipolar disorder and schizophrenia; TGCT cis rs7681440 0.874 rs1372522 chr4:90765280 A/G cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs2046867 0.818 rs67355490 chr3:72830935 T/C cg25664220 chr3:72788482 NA -0.58 -7.21 -0.54 4.9e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs981844 0.601 rs62323856 chr4:154623149 T/C cg14289246 chr4:154710475 SFRP2 1.0 8.1 0.59 4.42e-13 Response to statins (LDL cholesterol change); TGCT cis rs57221529 0.545 rs55955015 chr5:575182 A/G cg20362242 chr5:692897 TPPP 0.48 4.51 0.38 1.47e-5 Lung disease severity in cystic fibrosis; TGCT cis rs7666738 0.830 rs10012271 chr4:99065154 A/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1451375 0.657 rs12665904 chr7:50635399 A/G cg18232548 chr7:50535776 DDC 0.46 7.1 0.54 8.31e-11 Malaria; TGCT cis rs11696501 0.739 rs6104250 chr20:44251479 C/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg11941060 chr3:133502564 NA -0.26 -5.19 -0.42 8.21e-7 Iron status biomarkers; TGCT cis rs11214589 0.774 rs877137 chr11:113256330 C/T cg14159747 chr11:113255604 NA 0.37 4.54 0.38 1.3e-5 Neuroticism; TGCT cis rs36051895 0.623 rs10975024 chr9:5246403 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.35 -0.64 4.76e-16 Pediatric autoimmune diseases; TGCT cis rs1042445 1.000 rs1863622 chr3:186396616 C/T cg13908232 chr3:186371902 NA -0.42 -4.72 -0.39 6.38e-6 Blood protein levels; TGCT cis rs6840360 0.550 rs7675818 chr4:152690777 C/G cg22705602 chr4:152727874 NA -0.34 -5.91 -0.47 3.06e-8 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Vitiligo; TGCT cis rs71636778 0.509 rs34473788 chr1:27271519 A/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg21191810 chr6:118973309 C6orf204 -0.36 -4.77 -0.39 5.1e-6 Diastolic blood pressure; TGCT cis rs10504229 1.000 rs72652906 chr8:58188360 C/A cg08280861 chr8:58055591 NA 0.34 4.62 0.38 9.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs12989701 0.877 rs36085158 chr2:127869982 C/T cg08168897 chr2:127865431 BIN1 0.5 5.34 0.43 4.28e-7 Alzheimer's disease (late onset); TGCT cis rs6542838 0.702 rs4851167 chr2:99496303 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.67 -0.39 7.81e-6 Fear of minor pain; TGCT cis rs782590 0.774 rs782632 chr2:55898290 C/G cg03859395 chr2:55845619 SMEK2 0.85 9.64 0.65 9.63e-17 Metabolic syndrome; TGCT cis rs10510102 0.872 rs75831447 chr10:123713478 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs8072100 0.840 rs11079774 chr17:45479706 C/G cg08085267 chr17:45401833 C17orf57 -0.5 -5.69 -0.46 8.6e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4665809 1.000 rs7599132 chr2:26279810 A/T cg04944784 chr2:26401820 FAM59B 0.65 6.07 0.48 1.45e-8 Gut microbiome composition (summer); TGCT cis rs9926296 0.546 rs9935541 chr16:89905925 G/C cg03388025 chr16:89894329 SPIRE2 0.36 5.32 0.43 4.75e-7 Vitiligo; TGCT cis rs422249 0.896 rs174449 chr11:61640379 A/G cg01500311 chr11:61656094 FADS3 -0.4 -7.91 -0.58 1.24e-12 Trans fatty acid levels; TGCT cis rs6089584 0.706 rs6089625 chr20:60620622 T/C cg16423285 chr20:60520624 NA -0.6 -6.41 -0.5 2.76e-9 Body mass index; TGCT cis rs624899 0.522 rs645584 chr19:11612466 A/G cg01045132 chr19:11649571 CNN1 0.6 7.22 0.54 4.59e-11 Presence of antiphospholipid antibodies; TGCT cis rs7829975 0.501 rs2980769 chr8:8320291 G/A cg06636001 chr8:8085503 FLJ10661 0.79 7.36 0.55 2.24e-11 Mood instability; TGCT cis rs7904368 0.806 rs7899853 chr10:16857603 A/T cg14835575 chr10:16859367 RSU1 0.72 7.76 0.57 2.67e-12 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs9467711 0.790 rs13195401 chr6:26463574 G/T cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs4919694 0.901 rs74376228 chr10:104677662 G/C cg04362960 chr10:104952993 NT5C2 1.05 6.9 0.53 2.39e-10 Arsenic metabolism; TGCT cis rs9858542 0.903 rs11917431 chr3:49644012 C/T cg03060546 chr3:49711283 APEH -0.63 -5.48 -0.44 2.28e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7681440 0.904 rs1442153 chr4:90775719 T/G cg20003494 chr4:90757398 SNCA -0.56 -5.35 -0.43 4.11e-7 Dementia with Lewy bodies; TGCT cis rs1215050 0.818 rs165238 chr4:98712138 G/T cg17366294 chr4:99064904 C4orf37 0.52 5.57 0.45 1.54e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.84 0.46 4.3e-8 Bipolar disorder; TGCT cis rs16866061 1.000 rs17480230 chr2:225399864 G/A cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs13191362 1.000 rs13204013 chr6:163002480 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg09177884 chr7:1199841 ZFAND2A -0.72 -4.47 -0.37 1.72e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10540 1.000 rs61876332 chr11:487101 C/T cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs12497850 0.931 rs7430501 chr3:48890119 C/T cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs2888674 1.000 rs1006581 chr7:150511923 A/G cg10409299 chr7:150498843 TMEM176B;TMEM176A -0.26 -4.52 -0.38 1.44e-5 Forced expiratory volume in 1 second (occupational environmental exposures interaction); TGCT cis rs7552404 1.000 rs1498316 chr1:76159198 G/A cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs561341 0.629 rs7216107 chr17:30224419 G/A cg20587970 chr11:113659929 NA -0.53 -7.67 -0.57 4.47e-12 Hip circumference adjusted for BMI; TGCT cis rs1568889 1.000 rs33937991 chr11:28045260 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs1865760 0.534 rs72834629 chr6:26023032 C/T cg17042849 chr6:26104293 HIST1H4C -0.82 -6.93 -0.53 2.04e-10 Height; TGCT cis rs6500602 0.627 rs863501 chr16:4588394 G/C cg08645402 chr16:4508243 NA -0.21 -5.57 -0.45 1.53e-7 Schizophrenia; TGCT cis rs933688 1.000 rs332544 chr5:90778848 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 10.45 0.68 1.02e-18 Smoking behavior; TGCT cis rs372883 0.648 rs1003772 chr21:30736145 A/T cg24692254 chr21:30365293 RNF160 0.51 4.57 0.38 1.14e-5 Pancreatic cancer; TGCT cis rs4819052 0.851 rs875621 chr21:46682295 A/G cg06618935 chr21:46677482 NA -0.37 -5.44 -0.44 2.69e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8082590 1 rs8082590 chr17:17958402 G/A cg04398451 chr17:18023971 MYO15A 0.33 5.39 0.44 3.47e-7 Schizophrenia; TGCT cis rs2862064 1.000 rs7731951 chr5:156449685 A/T cg12943317 chr5:156479607 HAVCR1 0.44 5.66 0.45 9.9e-8 Platelet count; TGCT cis rs864745 0.967 rs849135 chr7:28196413 G/A cg23620719 chr7:28220237 JAZF1 -0.48 -4.45 -0.37 1.92e-5 Crohn's disease;Type 2 diabetes; TGCT cis rs7552404 0.690 rs12723575 chr1:76335203 T/C cg10523679 chr1:76189770 ACADM -0.67 -6.27 -0.49 5.47e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9467773 1.000 rs9461259 chr6:26504835 C/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs74544699 1.000 rs11574450 chr4:74847111 A/C cg16072462 chr4:74847758 PF4 1.02 5.45 0.44 2.56e-7 Growth-regulated protein alpha levels; TGCT cis rs11671005 0.735 rs56292587 chr19:58919066 A/T cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT cis rs12479064 0.724 rs112900993 chr2:99948805 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.57 -4.47 -0.37 1.71e-5 Chronic sinus infection; TGCT cis rs10507380 0.824 rs117389279 chr13:27923547 C/T cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs7824557 0.527 rs10109537 chr8:11239640 C/T cg21775007 chr8:11205619 TDH -0.67 -6.56 -0.51 1.28e-9 Retinal vascular caliber; TGCT cis rs6714710 0.603 rs17489454 chr2:98407350 C/T cg26665480 chr2:98280029 ACTR1B 0.64 6.06 0.48 1.53e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs11696501 0.688 rs6073842 chr20:44293841 G/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs11252926 0.527 rs10904093 chr10:436848 A/G cg18196295 chr10:418757 DIP2C -0.3 -5.2 -0.42 7.99e-7 Psychosis in Alzheimer's disease; TGCT cis rs7666738 0.830 rs9998803 chr4:99002519 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1998418 0.736 rs1006368 chr10:126346603 C/T cg03585084 chr10:126284563 LHPP 0.25 4.46 0.37 1.8e-5 Mean platelet volume; TGCT cis rs7829975 0.573 rs7842359 chr8:8797078 T/G cg06636001 chr8:8085503 FLJ10661 -0.7 -6.19 -0.49 8.23e-9 Mood instability; TGCT cis rs9393777 0.513 rs9368447 chr6:26646674 A/C cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs7089973 0.872 rs7918388 chr10:116614563 T/C cg03647239 chr10:116582469 FAM160B1 0.52 4.64 0.38 8.75e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs79349575 0.715 rs9894220 chr17:46989154 C/T cg07967210 chr17:47022446 SNF8 0.41 5.41 0.44 3.18e-7 Type 2 diabetes; TGCT cis rs9467711 0.606 rs9393705 chr6:26361011 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs13102973 0.720 rs13137300 chr4:135889460 G/A cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs6570726 1.000 rs386678 chr6:145869010 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.74 0.39 5.75e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4073582 0.576 rs556595 chr11:66058082 T/G cg16950941 chr11:66035639 RAB1B 0.57 5.15 0.42 9.9e-7 Gout; TGCT cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg07507251 chr3:52567010 NT5DC2 -0.41 -5.65 -0.45 1.07e-7 Bipolar disorder; TGCT cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs2439831 0.867 rs2255042 chr15:43834318 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.84 -5.79 -0.46 5.33e-8 Lung cancer in ever smokers; TGCT cis rs950027 0.572 rs12910764 chr15:45609360 T/C cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.89 -0.47 3.46e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs7647973 0.593 rs7620848 chr3:49828021 G/C cg03060546 chr3:49711283 APEH -0.63 -5.63 -0.45 1.12e-7 Menarche (age at onset); TGCT cis rs909674 0.731 rs6001594 chr22:39837472 C/T cg24399712 chr22:39784796 NA -1.07 -11.03 -0.7 4.05e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs713587 0.967 rs10182458 chr2:25150641 A/G cg15423357 chr2:25149977 NA 0.63 6.46 0.5 2.15e-9 Body mass index in non-asthmatics; TGCT cis rs739496 0.579 rs7980569 chr12:112281384 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7666738 0.830 rs1813251 chr4:98921170 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.1e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17197710 0.673 rs61896051 chr11:47313569 C/T cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6912958 1.000 rs6454630 chr6:88171357 C/G cg08069147 chr6:88032118 GJB7;C6orf162 0.58 5.45 0.44 2.59e-7 Monocyte percentage of white cells; TGCT cis rs9914544 0.545 rs12600851 chr17:18767518 T/A cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs7954584 0.616 rs10743186 chr12:122356436 C/T cg22168489 chr12:122356033 WDR66 0.23 5.55 0.45 1.63e-7 Mean corpuscular volume; TGCT cis rs17345786 0.906 rs72944107 chr3:101197190 C/T cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs651907 0.557 rs3094297 chr3:101399260 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 11.66 0.72 1.13e-21 Colorectal cancer; TGCT cis rs9638182 0.778 rs35332062 chr7:73012042 G/A cg14087351 chr7:73037990 MLXIPL -0.65 -5.07 -0.41 1.43e-6 Triglycerides; TGCT cis rs6988636 1.000 rs62521826 chr8:124186668 C/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs57590327 0.527 rs11917558 chr3:81610805 G/A cg07356753 chr3:81810745 GBE1 -0.59 -4.96 -0.41 2.23e-6 Extraversion; TGCT cis rs7647973 1.000 rs11710434 chr3:49346130 T/C cg07636037 chr3:49044803 WDR6 0.72 5.84 0.46 4.25e-8 Menarche (age at onset); TGCT cis rs7264396 0.790 rs6060526 chr20:34225302 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.28 4.74 0.39 5.75e-6 Total cholesterol levels; TGCT cis rs7267979 0.966 rs2261720 chr20:25260641 T/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6951245 0.832 rs79808627 chr7:1092519 C/G cg18402987 chr7:1209562 NA 0.56 5.07 0.41 1.4e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10507380 0.824 rs9512636 chr13:27920494 G/T cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs5750830 0.594 rs5757647 chr22:39775047 C/A cg02038168 chr22:39784481 NA -0.64 -5.48 -0.44 2.32e-7 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.851 rs8131143 chr21:46671646 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.57 -4.53 -0.38 1.35e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs950027 0.620 rs2461700 chr15:45640627 T/C cg14582100 chr15:45693742 SPATA5L1 0.47 6.05 0.48 1.59e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs3741404 0.665 rs12418535 chr11:63910980 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.88 9.59 0.65 1.28e-16 Platelet count; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg11905131 chr22:24372483 LOC391322 -0.98 -12.41 -0.74 1.79e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.59 5.3 0.43 5.06e-7 Height; TGCT cis rs7805747 0.961 rs10224210 chr7:151413194 T/C cg17611936 chr7:151411526 PRKAG2 0.56 6.64 0.51 8.81e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs7954584 0.520 rs1169095 chr12:122465738 G/A cg22168489 chr12:122356033 WDR66 -0.19 -4.52 -0.38 1.42e-5 Mean corpuscular volume; TGCT cis rs4689388 0.926 rs10937717 chr4:6295087 T/A cg25554036 chr4:6271136 WFS1 0.55 7.69 0.57 3.85e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.91 0.4 2.83e-6 Height; TGCT cis rs7119 0.604 rs2667781 chr15:77858619 A/C cg27398640 chr15:77910606 LINGO1 0.27 4.96 0.41 2.23e-6 Type 2 diabetes; TGCT cis rs11190604 0.943 rs9420792 chr10:102258439 C/T cg16342193 chr10:102329863 NA -0.4 -5.12 -0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1371867 0.875 rs2439456 chr8:101336874 C/T cg06636551 chr8:101224915 SPAG1 -0.45 -6.05 -0.48 1.55e-8 Atrioventricular conduction; TGCT trans rs17685 0.623 rs7782808 chr7:75768645 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs10540 1.000 rs117339389 chr11:505025 T/A cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs644799 0.526 rs534973 chr11:95633624 A/T cg25622487 chr11:95524042 FAM76B;CEP57 0.52 4.96 0.41 2.3e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs394563 0.591 rs11964335 chr6:149658101 A/T cg11245181 chr6:149772854 ZC3H12D 0.28 4.5 0.37 1.57e-5 Dupuytren's disease; TGCT cis rs9972944 0.729 rs7224482 chr17:63777949 C/A cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs7552404 0.824 rs1251079 chr1:76189445 C/T cg03433033 chr1:76189801 ACADM 0.92 14.93 0.8 1.79e-29 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11105298 0.891 rs10858879 chr12:89886578 A/T cg08166232 chr12:89918718 WDR51B;GALNT4 0.7 5.02 0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs459571 0.959 rs467379 chr9:136905474 C/T cg13789015 chr9:136890014 NCRNA00094 0.36 6.43 0.5 2.53e-9 Platelet distribution width; TGCT cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg07507251 chr3:52567010 NT5DC2 0.49 7.04 0.53 1.14e-10 Electroencephalogram traits; TGCT cis rs7666738 0.753 rs10004827 chr4:99037953 A/C cg18180107 chr4:99064573 C4orf37 0.57 5.23 0.42 7.1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9900497 0.569 rs2072327 chr17:19651482 G/T cg15323506 chr17:19619410 SLC47A2 -0.22 -5.62 -0.45 1.17e-7 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs10875595 0.836 rs7703869 chr5:140666494 C/T cg20560182 chr5:140700478 TAF7 -0.66 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs2046867 0.908 rs67967166 chr3:72794198 A/G cg25664220 chr3:72788482 NA -0.55 -6.95 -0.53 1.83e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7582180 0.663 rs2053263 chr2:100971407 A/G cg14675211 chr2:100938903 LONRF2 0.47 4.56 0.38 1.22e-5 Intelligence (multi-trait analysis); TGCT cis rs477895 0.639 rs35858916 chr11:63950529 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 6.34 0.49 3.93e-9 Mean platelet volume; TGCT cis rs12908161 0.959 rs3748376 chr15:85328352 C/T cg11189052 chr15:85197271 WDR73 0.71 5.82 0.46 4.75e-8 Schizophrenia; TGCT cis rs853679 0.546 rs200950 chr6:27835772 A/G cg08798685 chr6:27730294 NA -0.34 -4.69 -0.39 7.2e-6 Depression; TGCT cis rs7513165 0.932 rs11240694 chr1:204157973 C/T cg04791601 chr1:204159016 NA 0.26 5.06 0.41 1.47e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs1031925 0.687 rs6778196 chr3:51770429 C/T cg10583097 chr3:51429234 RBM15B -0.57 -4.94 -0.41 2.5e-6 Melanoma; TGCT cis rs259282 0.538 rs62124303 chr19:33113042 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.5 4.56 0.38 1.21e-5 Schizophrenia; TGCT cis rs4468007 0.505 rs4836866 chr9:124620787 G/A cg01549227 chr9:124980074 LHX6 -0.3 -4.55 -0.38 1.24e-5 Educational attainment; TGCT cis rs589448 0.967 rs634512 chr12:69754012 C/T cg11871910 chr12:69753446 YEATS4 0.87 10.07 0.67 8.72e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs6125597 1.000 rs6125597 chr20:47840772 T/C cg11220565 chr20:47934802 NA -0.3 -4.58 -0.38 1.13e-5 Intelligence (multi-trait analysis); TGCT cis rs72781680 0.898 rs72786288 chr2:24075416 G/T cg08917208 chr2:24149416 ATAD2B 0.77 4.69 0.39 7.06e-6 Lymphocyte counts; TGCT cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg22963979 chr7:1858916 MAD1L1 -0.45 -7.65 -0.57 4.91e-12 Schizophrenia; TGCT cis rs939658 0.805 rs35230534 chr15:79441093 T/C cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs10927875 0.619 rs2013019 chr1:16129320 T/C cg21385522 chr1:16154831 NA -0.74 -8.83 -0.62 8.18e-15 Dilated cardiomyopathy; TGCT cis rs77372450 0.551 rs6892478 chr5:157106968 C/T cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.51e-6 Bipolar disorder (body mass index interaction); TGCT cis rs3741151 1.000 rs79038783 chr11:73038746 C/G cg17517138 chr11:73019481 ARHGEF17 1.12 5.41 0.44 3.11e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs6725041 0.792 rs10048750 chr2:213090883 C/T cg16329650 chr2:213403929 ERBB4 -0.53 -4.58 -0.38 1.12e-5 QT interval (ambient particulate matter interaction); TGCT cis rs769267 0.965 rs12977937 chr19:19429975 C/G cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.52 0.38 1.44e-5 Tonsillectomy; TGCT cis rs909674 0.818 rs5757681 chr22:39845547 A/G cg05872129 chr22:39784769 NA -1.0 -9.92 -0.67 1.94e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2832191 0.791 rs57721945 chr21:30498744 T/C cg08807101 chr21:30365312 RNF160 -0.62 -5.8 -0.46 5.14e-8 Dental caries; TGCT cis rs137603 0.644 rs470082 chr22:39715140 C/T cg01093212 chr22:39715156 SNORD43;RPL3 -0.51 -4.95 -0.41 2.41e-6 Primary biliary cholangitis; TGCT cis rs7959452 0.535 rs10784771 chr12:69621264 A/G cg14784868 chr12:69753453 YEATS4 0.68 6.68 0.51 7.27e-10 Blood protein levels; TGCT cis rs860554 0.705 rs832170 chr1:201257016 G/A cg01022117 chr1:201258280 PKP1 0.34 5.01 0.41 1.87e-6 Panic disorder; TGCT cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg21724239 chr8:58056113 NA -0.37 -4.53 -0.38 1.39e-5 Developmental language disorder (linguistic errors); TGCT cis rs10927875 0.619 rs1806991 chr1:16129441 T/C cg21385522 chr1:16154831 NA -0.74 -8.95 -0.63 4.33e-15 Dilated cardiomyopathy; TGCT cis rs6840360 0.593 rs867800 chr4:152691470 T/C cg22705602 chr4:152727874 NA -0.34 -5.9 -0.47 3.24e-8 Intelligence (multi-trait analysis); TGCT cis rs4851254 1.000 rs4851254 chr2:100762937 C/G cg23118464 chr2:100721844 AFF3 0.69 5.19 0.42 8.17e-7 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.686 rs9390357 chr6:146129347 A/G cg05347473 chr6:146136440 FBXO30 0.47 4.48 0.37 1.65e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2172802 0.924 rs12715703 chr4:62432010 C/T cg04118610 chr4:62707027 LPHN3 -0.43 -4.68 -0.39 7.28e-6 Partial epilepsies; TGCT cis rs7617773 0.539 rs2017858 chr3:48382282 G/T cg11946769 chr3:48343235 NME6 0.55 4.6 0.38 1.02e-5 Coronary artery disease; TGCT cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7914558 1.000 rs67908413 chr10:104764989 T/C cg04362960 chr10:104952993 NT5C2 0.6 5.39 0.44 3.41e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg10150615 chr22:24372951 LOC391322 -1.01 -13.23 -0.77 1.86e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4460629 0.650 rs11264319 chr1:155083942 T/C cg23973274 chr1:155060172 NA -0.26 -4.72 -0.39 6.25e-6 Serum magnesium levels; TGCT cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.11 6.29 0.49 4.85e-9 Alzheimer's disease; TGCT cis rs3772130 0.962 rs11707504 chr3:121496734 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs909674 0.541 rs5750816 chr22:39810379 A/G cg01416388 chr22:39784598 NA 0.71 7.2 0.54 5.14e-11 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs35146811 0.695 rs858509 chr7:99821470 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs12477438 0.765 rs6737257 chr2:99683330 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs35146811 0.660 rs3779046 chr7:99779243 A/G cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg27454412 chr7:1067447 C7orf50 0.57 4.48 0.37 1.71e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg03188948 chr7:1209495 NA 0.46 6.38 0.5 3.24e-9 Longevity;Endometriosis; TGCT cis rs1372520 0.684 rs2619368 chr4:90729747 T/G cg01966878 chr4:90757139 SNCA -0.31 -4.84 -0.4 3.8e-6 Neuroticism; TGCT cis rs514406 0.763 rs6685599 chr1:53213172 G/A cg01802117 chr1:53393560 SCP2 0.44 5.26 0.43 6.2e-7 Monocyte count; TGCT cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.03 5.95 0.47 2.58e-8 Alzheimer's disease; TGCT cis rs6088580 0.660 rs6087592 chr20:33114503 A/G cg08999081 chr20:33150536 PIGU 0.29 5.54 0.45 1.75e-7 Glomerular filtration rate (creatinine); TGCT cis rs921943 0.554 rs163132 chr5:78285921 A/G cg17845680 chr5:78281827 ARSB 0.37 4.99 0.41 1.98e-6 Blood and toenail selenium levels;Blood trace element (Se levels); TGCT cis rs476633 0.708 rs8031159 chr15:41445199 T/C cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.77 -0.62 1.18e-14 Glomerular filtration rate (creatinine); TGCT cis rs17253792 0.642 rs10483648 chr14:56104278 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs425277 0.628 rs3107147 chr1:2048729 G/A cg24578937 chr1:2090814 PRKCZ -0.25 -6.0 -0.47 2.01e-8 Height; TGCT cis rs9394841 0.692 rs9369312 chr6:41841535 A/T cg08135965 chr6:41755394 TOMM6 0.57 5.17 0.42 9.15e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs686320 1.000 rs686320 chr11:65244538 G/C cg21890820 chr11:65308645 LTBP3 0.59 4.51 0.38 1.49e-5 Hip circumference adjusted for BMI; TGCT cis rs6912958 0.754 rs4707374 chr6:88255438 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg07061783 chr6:25882402 NA -0.66 -6.43 -0.5 2.45e-9 Intelligence (multi-trait analysis); TGCT cis rs7511006 0.893 rs5771104 chr22:50651839 C/T cg16473166 chr22:50639996 SELO 0.63 6.12 0.48 1.14e-8 Obesity-related traits; TGCT cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg20887711 chr4:1340912 KIAA1530 0.92 8.12 0.59 3.93e-13 Longevity; TGCT cis rs9911578 1.000 rs302848 chr17:56686454 C/T cg05425664 chr17:57184151 TRIM37 -0.57 -5.96 -0.47 2.47e-8 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.506 rs11920251 chr3:49356671 C/T cg07636037 chr3:49044803 WDR6 0.74 6.83 0.52 3.45e-10 Menarche (age at onset); TGCT cis rs208520 0.874 rs208514 chr6:66945520 G/A cg07460842 chr6:66804631 NA -0.9 -9.15 -0.63 1.45e-15 Exhaled nitric oxide output; TGCT trans rs66573146 0.831 rs68111914 chr4:6986677 C/T cg07817883 chr1:32538562 TMEM39B 1.3 6.83 0.52 3.41e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg08859206 chr1:53392774 SCP2 0.46 7.05 0.53 1.1e-10 Monocyte count; TGCT cis rs7104764 0.778 rs7930823 chr11:206767 C/T cg18336825 chr11:236787 PSMD13;SIRT3 -0.88 -9.3 -0.64 6.2e-16 Menarche (age at onset); TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs1023500 0.573 rs133370 chr22:42465260 T/C cg15557168 chr22:42548783 NA -0.22 -5.54 -0.45 1.76e-7 Schizophrenia; TGCT cis rs6484504 0.532 rs2150212 chr11:31255935 G/A cg26647111 chr11:31128758 NA -0.35 -4.85 -0.4 3.58e-6 Red blood cell count; TGCT cis rs7267979 0.934 rs2500399 chr20:25354694 T/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9303401 0.659 rs12940212 chr17:56674474 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs12220238 0.818 rs10430521 chr10:75913590 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs61867294 0.553 rs6584646 chr10:106709239 C/T cg08000847 chr10:105880925 C10orf78 0.47 4.48 0.37 1.64e-5 Schizophrenia; TGCT cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg27454412 chr7:1067447 C7orf50 0.62 4.68 0.39 7.54e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6860806 0.661 rs2136188 chr5:131577514 A/G cg24060327 chr5:131705240 SLC22A5 0.57 5.65 0.45 1.03e-7 Breast cancer; TGCT cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg15691649 chr6:25882328 NA -0.36 -4.71 -0.39 6.5e-6 Blood metabolite levels; TGCT cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg24829409 chr8:58192753 C8orf71 -0.57 -4.72 -0.39 6.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs2594989 0.943 rs4684780 chr3:11478960 C/T cg00170343 chr3:11313890 ATG7 0.63 4.96 0.41 2.27e-6 Circulating chemerin levels; TGCT trans rs208520 0.909 rs9453672 chr6:66991431 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.79 7.05 0.53 1.12e-10 Exhaled nitric oxide output; TGCT cis rs936229 0.749 rs6495127 chr15:75194490 C/T cg10253484 chr15:75165896 SCAMP2 -0.77 -6.52 -0.51 1.56e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs7772486 0.743 rs2092262 chr6:146037105 C/T cg23711669 chr6:146136114 FBXO30 -0.83 -8.95 -0.63 4.23e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs8056742 0.642 rs12927887 chr16:85031784 G/A cg00229868 chr16:85520891 NA 0.37 4.64 0.38 8.75e-6 Amyotrophic lateral sclerosis; TGCT cis rs28595532 0.920 rs114584210 chr4:119773363 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs2760061 0.626 rs594916 chr1:228133544 C/A cg18477163 chr1:228402036 OBSCN -0.32 -6.34 -0.49 3.86e-9 Diastolic blood pressure; TGCT cis rs6665290 0.836 rs56029302 chr1:227203390 G/A cg10327440 chr1:227177885 CDC42BPA -0.92 -16.13 -0.82 3.09e-32 Myeloid white cell count; TGCT cis rs7248779 0.512 rs7250002 chr19:2413188 A/G cg22729335 chr19:2427816 TIMM13 1.13 13.41 0.77 6.73e-26 Cortisol levels (saliva); TGCT cis rs7523273 1.000 rs12184327 chr1:207978780 A/G cg22525895 chr1:207977042 MIR29B2 -0.49 -8.61 -0.61 2.78e-14 Schizophrenia; TGCT cis rs3820068 0.603 rs72647138 chr1:15980929 C/T cg05660106 chr1:15850417 CASP9 0.79 7.46 0.56 1.29e-11 Systolic blood pressure; TGCT cis rs921968 0.607 rs2465100 chr2:219551044 A/T cg02176678 chr2:219576539 TTLL4 -0.33 -4.45 -0.37 1.92e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs9467773 1.000 rs6456733 chr6:26566804 C/T cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs7100689 0.646 rs7077712 chr10:82134894 A/G cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg03188948 chr7:1209495 NA 0.42 5.57 0.45 1.51e-7 Longevity;Endometriosis; TGCT cis rs36051895 0.659 rs12337134 chr9:5061578 G/A cg02405213 chr9:5042618 JAK2 -0.73 -9.89 -0.66 2.38e-17 Pediatric autoimmune diseases; TGCT cis rs6424115 0.708 rs34570472 chr1:24191720 A/G cg15997130 chr1:24165203 NA -0.68 -6.62 -0.51 9.92e-10 Immature fraction of reticulocytes; TGCT cis rs9910055 0.636 rs7089 chr17:42269017 T/C cg13607699 chr17:42295918 UBTF 0.6 5.48 0.44 2.23e-7 Total body bone mineral density; TGCT cis rs12477438 0.520 rs4347885 chr2:99804007 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs9303401 0.659 rs11079357 chr17:56902778 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs250677 1.000 rs250677 chr5:148433549 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.81 0.4 4.23e-6 Breast cancer; TGCT cis rs35771425 0.626 rs6677230 chr1:211652902 A/C cg10512769 chr1:211675356 NA -0.25 -4.49 -0.37 1.59e-5 Educational attainment (years of education); TGCT cis rs72781680 0.716 rs2712071 chr2:23990419 A/G cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg24250549 chr1:154909240 PMVK 0.62 6.28 0.49 5.29e-9 Prostate cancer; TGCT cis rs12541335 0.579 rs59283125 chr8:22212311 G/A cg02788857 chr8:22132959 PIWIL2 0.3 5.45 0.44 2.62e-7 Hypertriglyceridemia; TGCT cis rs1981331 0.609 rs57896262 chr21:48028188 C/T cg17243659 chr21:48055224 PRMT2 1.13 6.28 0.49 5.15e-9 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs2249625 0.545 rs9791273 chr6:72891016 G/T cg08500200 chr6:72892038 RIMS1 0.42 4.58 0.38 1.14e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs2760061 0.599 rs644794 chr1:228148670 T/C cg02753203 chr1:228287806 NA -0.34 -6.55 -0.51 1.4e-9 Diastolic blood pressure; TGCT cis rs710216 1.000 rs710216 chr1:43428757 A/G cg03128534 chr1:43423976 SLC2A1 0.59 4.55 0.38 1.28e-5 Red cell distribution width; TGCT cis rs514406 0.584 rs7524702 chr1:53197830 G/A cg24675658 chr1:53192096 ZYG11B 0.84 10.42 0.68 1.22e-18 Monocyte count; TGCT cis rs4073582 0.595 rs801741 chr11:65917084 A/G cg16950941 chr11:66035639 RAB1B 0.55 5.38 0.43 3.59e-7 Gout; TGCT cis rs2242116 0.796 rs7645278 chr3:46974100 A/C cg27129171 chr3:47204927 SETD2 0.65 6.44 0.5 2.43e-9 Birth weight; TGCT cis rs9549367 0.756 rs2302756 chr13:113900197 G/A cg18105134 chr13:113819100 PROZ 0.34 5.6 0.45 1.3e-7 Platelet distribution width; TGCT cis rs9549260 0.727 rs4603422 chr13:41148353 T/C cg21288729 chr13:41239152 FOXO1 1.0 10.37 0.68 1.61e-18 Red blood cell count; TGCT cis rs6570726 0.935 rs397418 chr6:145842362 C/T cg23711669 chr6:146136114 FBXO30 0.7 6.83 0.52 3.42e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs13424612 0.896 rs12467120 chr2:240894275 A/G cg26363272 chr2:240904871 NDUFA10 -0.31 -5.15 -0.42 1e-6 Odorant perception (isobutyraldehyde); TGCT cis rs4851254 0.660 rs60697219 chr2:100699507 G/A cg04109781 chr2:100722022 AFF3 0.46 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs11096990 0.819 rs4974991 chr4:39194767 T/A cg20847110 chr4:39482781 LOC401127 -0.17 -4.5 -0.37 1.53e-5 Cognitive function; TGCT cis rs4819052 0.851 rs13052344 chr21:46676101 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7940866 0.845 rs10894294 chr11:130830748 G/T cg05962950 chr11:130786565 SNX19 0.67 5.48 0.44 2.31e-7 Schizophrenia; TGCT cis rs433598 0.765 rs163265 chr16:20661809 A/G cg16616769 chr16:19727142 IQCK;C16orf88 -0.21 -4.68 -0.39 7.35e-6 Schizophrenia; TGCT cis rs67072384 0.818 rs1872127 chr11:72465085 G/A cg03713592 chr11:72463424 ARAP1 -0.88 -4.77 -0.39 5.04e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs11249608 0.548 rs7704565 chr5:178473923 G/C cg01312482 chr5:178451176 ZNF879 -0.5 -4.93 -0.41 2.55e-6 Pubertal anthropometrics; TGCT trans rs877282 0.898 rs2004478 chr10:770709 C/A cg22713356 chr15:30763199 NA 1.21 10.47 0.69 8.99e-19 Uric acid levels; TGCT cis rs7666738 0.830 rs1426667 chr4:98949772 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg23708337 chr7:1209742 NA 0.56 5.09 0.42 1.31e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs75686122 0.772 rs76370225 chr8:104520027 A/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs2880765 0.835 rs7162502 chr15:86044473 G/T cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs12681287 0.609 rs13281414 chr8:87495254 A/C cg27223183 chr8:87520930 FAM82B -0.92 -6.79 -0.52 4.12e-10 Caudate activity during reward; TGCT cis rs7584330 0.955 rs13432426 chr2:238388631 T/G cg14458575 chr2:238380390 NA 0.48 7.42 0.55 1.66e-11 Prostate cancer; TGCT cis rs904251 0.523 rs1776455 chr6:37482923 A/T cg08126542 chr6:37504118 NA -0.41 -6.05 -0.48 1.57e-8 Cognitive performance; TGCT cis rs7216064 1.000 rs8067892 chr17:65837983 A/G cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs77372450 0.551 rs77213903 chr5:157106186 C/G cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.51e-6 Bipolar disorder (body mass index interaction); TGCT cis rs1857353 0.803 rs17645210 chr1:75898049 T/C cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg27535305 chr1:53392650 SCP2 -0.24 -4.73 -0.39 5.98e-6 Monocyte count; TGCT cis rs6088590 0.931 rs6088624 chr20:33436852 T/A cg24642439 chr20:33292090 TP53INP2 0.69 6.21 0.49 7.16e-9 Coronary artery disease; TGCT cis rs806795 0.605 rs6935954 chr6:26255451 A/G cg13736514 chr6:26305472 NA -0.31 -4.67 -0.39 7.58e-6 Mosquito bite size; TGCT cis rs77741769 0.529 rs12579868 chr12:121207147 C/T cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.54e-5 Mean corpuscular volume; TGCT cis rs7607369 0.572 rs629177 chr2:219454801 T/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs6430585 0.583 rs4988201 chr2:136618507 A/G cg07169764 chr2:136633963 MCM6 1.22 12.03 0.73 1.46e-22 Corneal structure; TGCT cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg08219700 chr8:58056026 NA 0.3 4.55 0.38 1.25e-5 Developmental language disorder (linguistic errors); TGCT cis rs1218582 0.711 rs4845677 chr1:154838050 C/T cg09359103 chr1:154839909 KCNN3 -0.71 -14.31 -0.79 4.89e-28 Prostate cancer; TGCT cis rs11673344 0.504 rs6510592 chr19:37624332 G/C cg08039142 chr19:36980659 ZNF566 0.51 4.65 0.39 8.51e-6 Obesity-related traits; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.96 -12.29 -0.74 3.32e-23 Prudent dietary pattern; TGCT cis rs9860250 0.537 rs1449317 chr3:100761838 C/T cg05801080 chr3:100119813 LNP1;TOMM70A 0.54 4.44 0.37 1.96e-5 Optic disc area; TGCT cis rs882300 0.900 rs12691875 chr2:136915698 C/A cg05194412 chr2:137003533 NA 0.25 4.73 0.39 6.09e-6 Multiple sclerosis;Electrocardiographic traits; TGCT cis rs1008375 0.898 rs2079892 chr4:17577163 G/A cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7552404 0.731 rs11161845 chr1:76367559 T/C cg03433033 chr1:76189801 ACADM 0.77 7.43 0.56 1.5e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs7072216 0.763 rs10736129 chr10:100171571 C/T cg26618903 chr10:100175079 PYROXD2 0.4 4.49 0.37 1.64e-5 Metabolite levels; TGCT cis rs922182 0.617 rs17777266 chr15:64241242 A/G cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.33e-10 Blood protein levels; TGCT cis rs2412459 0.611 rs4924402 chr15:40245754 C/T cg25407064 chr15:40226267 EIF2AK4 -0.72 -4.7 -0.39 6.72e-6 Response to haloperidol in psychosis; TGCT cis rs854765 0.604 rs12948749 chr17:17949802 G/A cg04398451 chr17:18023971 MYO15A 0.31 4.84 0.4 3.76e-6 Total body bone mineral density; TGCT cis rs7208859 0.623 rs8081299 chr17:29104296 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.71 0.39 6.51e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4561483 0.549 rs33659 chr16:11963361 A/G cg08843971 chr16:11963173 GSPT1 -0.32 -6.3 -0.49 4.78e-9 Testicular germ cell tumor; TGCT cis rs644799 0.648 rs1255178 chr11:95471908 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.51 5.17 0.42 9.05e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs4332037 0.539 rs11763750 chr7:2080114 G/A cg25206134 chr2:45395956 NA 0.97 7.28 0.55 3.36e-11 Bipolar disorder; TGCT cis rs17384381 0.953 rs11161599 chr1:85795965 A/G cg16011679 chr1:85725395 C1orf52 -0.72 -6.12 -0.48 1.14e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs265548 0.595 rs265543 chr19:17904260 T/G cg21960279 chr19:17905606 B3GNT3 0.49 5.48 0.44 2.3e-7 Tumor biomarkers; TGCT cis rs1129187 0.755 rs2296804 chr6:42931261 C/G cg27588902 chr6:42928151 GNMT -0.57 -6.87 -0.53 2.76e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs56104184 0.779 rs73061627 chr19:49360418 C/T cg15549821 chr19:49342101 PLEKHA4 -0.77 -8.88 -0.62 6.4e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6952808 0.636 rs6461005 chr7:1947687 A/G cg22963979 chr7:1858916 MAD1L1 -0.36 -5.49 -0.44 2.18e-7 Bipolar disorder and schizophrenia; TGCT cis rs72634258 0.519 rs35197830 chr1:7930983 A/G cg26816564 chr1:7831052 VAMP3 0.62 4.99 0.41 1.98e-6 Inflammatory bowel disease; TGCT cis rs7772486 0.764 rs7762562 chr6:146158994 T/C cg23711669 chr6:146136114 FBXO30 0.89 10.01 0.67 1.2e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg20007245 chr22:24372913 LOC391322 0.79 8.72 0.62 1.55e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9814567 0.806 rs12637301 chr3:134317966 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs9951602 0.512 rs73494176 chr18:76644895 T/C cg02800362 chr5:177631904 HNRNPAB 1.14 13.02 0.76 6.04e-25 Obesity-related traits; TGCT cis rs853679 0.517 rs9393898 chr6:28130376 G/T cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7412746 0.622 rs11552229 chr1:150783985 T/C cg09365446 chr1:150670422 GOLPH3L 0.37 5.41 0.44 3.07e-7 Melanoma; TGCT cis rs669446 0.562 rs10890275 chr1:44194216 T/G cg12908607 chr1:44402522 ARTN -0.62 -7.25 -0.55 3.99e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs1348850 1.000 rs3927978 chr2:178443854 A/G cg22681709 chr2:178499509 PDE11A 0.37 4.81 0.4 4.23e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7714584 1.000 rs7734778 chr5:150256556 G/A cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg17971929 chr21:40555470 PSMG1 0.69 6.15 0.48 9.7e-9 Cognitive function; TGCT cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.4 -4.5 -0.37 1.55e-5 Height; TGCT cis rs9486715 0.867 rs9386500 chr6:96889845 A/C cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs3809566 0.676 rs4775607 chr15:63328007 C/T cg00520135 chr15:63333846 TPM1 -0.42 -5.32 -0.43 4.75e-7 Platelet count; TGCT cis rs9467773 1.000 rs12526680 chr6:26550954 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.55 0.51 1.36e-9 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.577 rs6542942 chr2:100985378 G/T cg14675211 chr2:100938903 LONRF2 0.49 4.69 0.39 7.2e-6 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs1865760 0.963 rs9356991 chr6:25901758 C/A cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs1008375 0.932 rs12500947 chr4:17603424 C/T cg18681998 chr4:17616180 MED28 0.99 9.69 0.66 7.08e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12477438 0.501 rs7608938 chr2:99782226 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs1371867 0.875 rs1788184 chr8:101335106 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs3820068 0.603 rs7531396 chr1:15969870 G/C cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.25e-13 Systolic blood pressure; TGCT cis rs4713118 0.513 rs149959 chr6:28013854 T/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.75 0.39 5.48e-6 Parkinson's disease; TGCT cis rs4654899 1.000 rs72865329 chr1:21517567 G/A cg01072550 chr1:21505969 NA -0.5 -8.03 -0.59 6.27e-13 Superior frontal gyrus grey matter volume; TGCT cis rs1008375 1.000 rs28501187 chr4:17643620 G/A cg18681998 chr4:17616180 MED28 1.0 11.93 0.73 2.54e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg03806693 chr22:41940476 POLR3H 1.14 12.74 0.75 2.72e-24 Vitiligo; TGCT cis rs61656020 1 rs61656020 chr16:1882221 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.43 -4.67 -0.39 7.61e-6 Ankle injury; TGCT cis rs9388451 0.626 rs1268074 chr6:126107791 G/C cg05901451 chr6:126070800 HEY2 -0.94 -11.88 -0.73 3.44e-22 Brugada syndrome; TGCT cis rs769267 0.965 rs2017964 chr19:19387149 T/C cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs9486719 1.000 rs12191653 chr6:96903898 T/C cg06623918 chr6:96969491 KIAA0776 -0.98 -8.77 -0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs7095607 0.730 rs1900012 chr10:69953942 G/A cg18986048 chr10:69913749 MYPN 0.58 6.79 0.52 4.14e-10 Lung function (FVC); TGCT cis rs1538970 0.774 rs67683090 chr1:45977803 T/G cg05343316 chr1:45956843 TESK2 0.82 6.69 0.51 6.98e-10 Platelet count; TGCT cis rs12048904 0.964 rs8888 chr1:101338324 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.55 5.09 0.42 1.31e-6 Multiple sclerosis; TGCT cis rs17221829 0.673 rs11018700 chr11:89382066 A/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 8.95e-6 Anxiety in major depressive disorder; TGCT cis rs7917772 0.503 rs10883732 chr10:104293461 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs73110464 0.609 rs727266 chr12:53356411 C/T cg25025879 chr12:53359317 NA -0.52 -5.7 -0.46 8.29e-8 Cancer (pleiotropy); TGCT cis rs10501293 0.703 rs10768909 chr11:43020427 G/A cg03447554 chr11:43094025 NA 0.44 6.29 0.49 4.97e-9 Cognitive performance; TGCT cis rs6845621 0.727 rs10020540 chr4:18908628 T/C cg12196642 chr4:18937545 NA -0.25 -4.5 -0.37 1.53e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs1371867 0.846 rs1788191 chr8:101260844 C/T cg00191853 chr8:101177733 SPAG1 0.22 4.5 0.37 1.53e-5 Atrioventricular conduction; TGCT cis rs736408 1.000 rs736408 chr3:52835354 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 4.74 0.39 5.77e-6 Bipolar disorder; TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.04 0.82 5e-32 Prudent dietary pattern; TGCT cis rs922182 0.613 rs6494454 chr15:64233563 C/A cg02919090 chr15:64263738 DAPK2 -0.33 -6.14 -0.48 1.05e-8 Blood protein levels; TGCT cis rs5769707 0.967 rs2071904 chr22:50034477 C/T cg10356904 chr22:49881777 NA -0.22 -4.52 -0.38 1.4e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs61990749 0.597 rs176955 chr14:78181220 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs7829975 0.653 rs13259070 chr8:8690787 C/T cg08975724 chr8:8085496 FLJ10661 0.58 5.13 0.42 1.1e-6 Mood instability; TGCT cis rs13108904 0.557 rs1680041 chr4:1238521 C/T cg20887711 chr4:1340912 KIAA1530 -0.58 -4.97 -0.41 2.17e-6 Obesity-related traits; TGCT cis rs12477438 0.501 rs6753063 chr2:99801469 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs9308731 0.863 rs616582 chr2:111941995 T/C cg04202892 chr2:111875749 ACOXL 0.45 4.83 0.4 3.9e-6 Chronic lymphocytic leukemia; TGCT cis rs9928842 0.824 rs889515 chr16:75251299 T/C cg09066997 chr16:75300724 BCAR1 0.26 4.52 0.38 1.41e-5 Alcoholic chronic pancreatitis; TGCT cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs2486288 0.656 rs11632724 chr15:45550791 G/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs6684514 1.000 rs10908499 chr1:156279176 G/C cg16558208 chr1:156270281 VHLL 0.48 9.61 0.65 1.13e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7223966 1.000 rs7222060 chr17:61868279 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7312933 0.531 rs1796380 chr12:42791543 T/G cg19980929 chr12:42632907 YAF2 -0.41 -5.8 -0.46 5.14e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs16966142 1.000 rs3890534 chr16:89835289 A/G cg04287289 chr16:89883240 FANCA -0.79 -4.9 -0.4 2.93e-6 Caffeine consumption; TGCT cis rs2295359 1.000 rs2295359 chr1:67635950 G/A cg12940439 chr1:67600707 NA 0.54 5.66 0.45 9.77e-8 Psoriasis; TGCT cis rs4319547 0.656 rs10161534 chr12:122873864 T/C cg08088222 chr12:122070432 ORAI1 0.25 4.45 0.37 1.89e-5 Body mass index; TGCT cis rs12693043 0.727 rs9789707 chr2:175412112 G/C cg11778734 chr2:175439522 WIPF1 -0.4 -5.15 -0.42 9.9e-7 Urate levels (BMI interaction); TGCT cis rs35146811 0.586 rs6964754 chr7:99589404 G/A cg13334819 chr7:99746414 C7orf59 -0.65 -5.74 -0.46 6.78e-8 Coronary artery disease; TGCT cis rs7246657 0.943 rs10415937 chr19:37830064 T/G cg03233940 chr19:37894644 NA -0.34 -4.53 -0.38 1.34e-5 Coronary artery calcification; TGCT cis rs3733585 0.699 rs6449157 chr4:9960442 G/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.55 -0.51 1.41e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2153535 0.580 rs4960411 chr6:8438231 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs2688608 0.620 rs11000767 chr10:75516626 G/T cg04320760 chr10:75533139 FUT11 -0.36 -5.66 -0.45 9.83e-8 Inflammatory bowel disease; TGCT cis rs813218 0.523 rs652026 chr3:99442809 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.04 0.41 1.59e-6 Orofacial clefts; TGCT cis rs76878669 0.561 rs10791872 chr11:66138434 C/G cg18002602 chr11:66138449 SLC29A2 -0.53 -6.49 -0.5 1.89e-9 Educational attainment (years of education); TGCT cis rs7727544 0.716 rs7720230 chr5:131592405 T/G cg21474247 chr5:131268130 NA 0.31 4.63 0.38 9.21e-6 Blood metabolite levels; TGCT cis rs875971 1.000 rs778706 chr7:65860424 A/G cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs877282 0.945 rs10904550 chr10:774177 C/T cg17470449 chr10:769945 NA 0.3 4.77 0.39 5.05e-6 Uric acid levels; TGCT cis rs4919669 0.668 rs17114808 chr10:104391285 C/T cg05855489 chr10:104503620 C10orf26 0.81 4.83 0.4 3.99e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs910316 0.789 rs12894419 chr14:75471802 C/T cg08847533 chr14:75593920 NEK9 0.83 8.89 0.62 5.99e-15 Height; TGCT cis rs763121 0.889 rs2267390 chr22:38889657 C/T cg06022373 chr22:39101656 GTPBP1 0.76 7.43 0.55 1.56e-11 Menopause (age at onset); TGCT cis rs11031096 0.655 rs1822289 chr11:4212184 T/C cg18678763 chr11:4115507 RRM1 -0.44 -5.69 -0.46 8.66e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9534288 0.762 rs3934247 chr13:46549137 C/T cg15192986 chr13:46630673 CPB2 -0.53 -7.68 -0.57 4.13e-12 Blood protein levels; TGCT cis rs58722170 0.610 rs55884510 chr1:38068943 G/A cg17933807 chr1:38061675 GNL2 -0.84 -8.39 -0.6 9.28e-14 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs9457247 0.935 rs2149093 chr6:167373045 T/C cg23791538 chr6:167370224 RNASET2 0.53 5.07 0.41 1.39e-6 Crohn's disease; TGCT cis rs7267979 1.000 rs6050590 chr20:25384994 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9902453 0.904 rs11654983 chr17:28370042 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -7.96 -0.58 9.19e-13 Coffee consumption (cups per day); TGCT cis rs57590327 0.555 rs3943556 chr3:81738892 G/C cg07356753 chr3:81810745 GBE1 -0.78 -7.36 -0.55 2.18e-11 Extraversion; TGCT cis rs7635838 0.963 rs35834806 chr3:11414100 C/T cg00170343 chr3:11313890 ATG7 0.61 5.91 0.47 3.14e-8 HDL cholesterol; TGCT cis rs6546537 0.550 rs72837959 chr2:69780762 C/T cg10773587 chr2:69614142 GFPT1 -0.65 -5.94 -0.47 2.7e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs7180079 0.563 rs6494486 chr15:64996193 G/A cg03791955 chr15:65024147 NA 0.28 5.45 0.44 2.61e-7 Monocyte count; TGCT cis rs7586879 1.000 rs7586879 chr2:25116977 C/T cg01884057 chr2:25150051 NA 0.29 5.07 0.41 1.38e-6 Body mass index; TGCT cis rs7611238 0.538 rs4677842 chr3:195137216 C/T cg27323046 chr3:195102265 ACAP2 0.38 5.13 0.42 1.09e-6 Body mass index; TGCT cis rs2242116 0.727 rs6442040 chr3:46963035 C/A cg02527881 chr3:46936655 PTH1R -0.31 -5.77 -0.46 5.88e-8 Birth weight; TGCT cis rs11711311 1.000 rs7622515 chr3:113472538 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs225245 0.791 rs2285742 chr17:34018682 C/T cg05299278 chr17:33885742 SLFN14 0.22 4.7 0.39 6.92e-6 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs11671005 0.735 rs11084543 chr19:58932701 T/C cg13877915 chr19:58951672 ZNF132 0.65 5.14 0.42 1.04e-6 Mean platelet volume; TGCT cis rs2797160 1.000 rs1739380 chr6:126012858 T/C cg05901451 chr6:126070800 HEY2 0.74 6.12 0.48 1.15e-8 Endometrial cancer; TGCT cis rs8084125 0.765 rs72981157 chr18:74944238 A/G cg05528293 chr18:74961138 GALR1 0.49 4.84 0.4 3.74e-6 Obesity-related traits; TGCT cis rs9611565 0.625 rs2076199 chr22:41903743 G/T cg03806693 chr22:41940476 POLR3H -0.98 -10.44 -0.68 1.11e-18 Vitiligo; TGCT cis rs7103648 0.808 rs7103835 chr11:47461693 G/A cg20307385 chr11:47447363 PSMC3 0.96 10.27 0.68 2.85e-18 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs6500602 0.727 rs4786515 chr16:4578133 T/A cg08645402 chr16:4508243 NA 0.19 5.25 0.43 6.32e-7 Schizophrenia; TGCT cis rs28595532 0.920 rs114019902 chr4:119755564 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs3796352 1.000 rs34313969 chr3:52995166 A/G cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs8014204 0.566 rs11629369 chr14:75162021 G/A cg06637938 chr14:75390232 RPS6KL1 0.61 5.51 0.44 1.98e-7 Caffeine consumption; TGCT trans rs9388451 0.839 rs4897155 chr6:126095144 C/A cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.38 -0.6 9.89e-14 Brugada syndrome; TGCT cis rs1865760 0.566 rs9467663 chr6:26021456 C/G cg17042849 chr6:26104293 HIST1H4C -0.61 -5.13 -0.42 1.07e-6 Height; TGCT cis rs13191362 1.000 rs34052221 chr6:163160803 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.14 9.38 0.64 4.1e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.830 rs28802909 chr4:99039410 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10779751 1.000 rs2076655 chr1:11289161 A/G cg08854313 chr1:11322531 MTOR -0.92 -10.07 -0.67 8.5e-18 Body mass index; TGCT cis rs57221529 0.825 rs7443550 chr5:578404 G/T cg09021430 chr5:549028 NA -0.37 -5.16 -0.42 9.7e-7 Lung disease severity in cystic fibrosis; TGCT cis rs2836950 0.502 rs12627205 chr21:40630027 C/T cg06238570 chr21:40685208 BRWD1 -0.61 -6.2 -0.49 7.81e-9 Menarche (age at onset); TGCT cis rs1005224 0.963 rs11623813 chr14:76138194 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.63 -5.66 -0.45 1.01e-7 Large artery stroke; TGCT cis rs858239 0.601 rs987257 chr7:23147840 G/A cg05602783 chr7:23145260 KLHL7 -0.66 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs3008870 1.000 rs1137656 chr1:67451602 A/C cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs7586879 0.616 rs6545813 chr2:25131287 C/T cg15423357 chr2:25149977 NA 0.52 5.03 0.41 1.65e-6 Body mass index; TGCT cis rs3008870 0.583 rs11208985 chr1:67464666 G/A cg08660285 chr1:67390436 MIER1;WDR78 -0.97 -8.16 -0.59 3.17e-13 Lymphocyte percentage of white cells; TGCT cis rs751728 1.000 rs3793079 chr6:33767788 T/A cg00334056 chr6:33755658 LEMD2 -0.25 -4.52 -0.38 1.44e-5 Crohn's disease; TGCT cis rs7772486 0.846 rs866473 chr6:146353414 A/C cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6912958 0.500 rs2025486 chr6:87796886 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.73 -7.35 -0.55 2.37e-11 Monocyte percentage of white cells; TGCT cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg13770153 chr20:60521292 NA -0.6 -7.67 -0.57 4.3e-12 Body mass index; TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg01171360 chr6:293285 DUSP22 -0.78 -7.98 -0.58 8.31e-13 Menopause (age at onset); TGCT cis rs9653442 0.545 rs11123810 chr2:100759285 T/C cg07810366 chr2:100720526 AFF3 -0.35 -5.06 -0.41 1.48e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs597539 0.552 rs10896384 chr11:68720011 A/G cg21862992 chr11:68658383 NA -0.43 -5.96 -0.47 2.4e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12510870 0.599 rs7695792 chr4:74453064 T/C cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs28595532 0.841 rs10019311 chr4:119785458 G/A cg00700008 chr4:120138107 USP53 0.49 4.48 0.37 1.71e-5 Cannabis dependence symptom count; TGCT cis rs3862435 0.764 rs2589948 chr15:90952232 G/A cg14166756 chr15:90894880 ZNF774 -0.29 -4.68 -0.39 7.31e-6 Response to exercise (triglyceride level interaction); TGCT cis rs9928842 0.765 rs6564221 chr16:75224971 C/T cg09066997 chr16:75300724 BCAR1 0.29 5.13 0.42 1.09e-6 Alcoholic chronic pancreatitis; TGCT trans rs4332037 1.000 rs6947019 chr7:1950337 G/A cg10840412 chr1:235813424 GNG4 1.05 8.28 0.6 1.71e-13 Bipolar disorder; TGCT cis rs6089829 0.589 rs73921629 chr20:61676036 G/C cg03213289 chr20:61660250 NA -0.55 -5.49 -0.44 2.18e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2013441 0.965 rs8068720 chr17:20214171 G/T cg18979559 chr17:20280153 CCDC144C -0.47 -4.93 -0.4 2.63e-6 Obesity-related traits; TGCT cis rs7843479 0.601 rs11135764 chr8:21814004 A/G cg17168535 chr8:21777572 XPO7 0.81 8.33 0.6 1.25e-13 Mean corpuscular volume; TGCT cis rs10089 0.953 rs1432615 chr5:127395371 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs2439831 0.702 rs2467402 chr15:44024490 A/C cg02155558 chr15:43621948 ADAL;LCMT2 -0.76 -5.34 -0.43 4.36e-7 Lung cancer in ever smokers; TGCT cis rs12579753 0.879 rs1986537 chr12:82156475 G/C cg07988820 chr12:82153109 PPFIA2 -0.67 -7.45 -0.56 1.4e-11 Resting heart rate; TGCT cis rs9430161 0.579 rs11121669 chr1:11039567 T/C cg27631724 chr1:11040367 C1orf127 0.55 6.58 0.51 1.2e-9 Ewing sarcoma; TGCT cis rs7523050 0.643 rs67091034 chr1:109402567 C/G cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs7829975 0.542 rs7844374 chr8:8798684 A/G cg06636001 chr8:8085503 FLJ10661 -0.76 -6.71 -0.52 6.14e-10 Mood instability; TGCT cis rs79057730 0.527 rs34519158 chr7:811114 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.64 5.23 0.43 6.91e-7 Initial pursuit acceleration; TGCT trans rs17685 0.558 rs60787921 chr7:75792844 C/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs55962025 0.842 rs362271 chr4:3235518 C/T cg06533319 chr4:3265114 C4orf44 0.24 4.87 0.4 3.26e-6 Parental longevity (mother's age at death); TGCT cis rs597539 0.552 rs10896384 chr11:68720011 A/G cg06112835 chr11:68658793 MRPL21 -0.43 -7.19 -0.54 5.3e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9467711 0.516 rs555460 chr6:25870655 C/T cg12310025 chr6:25882481 NA -0.76 -5.11 -0.42 1.18e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs11148252 0.774 rs56033750 chr13:52747278 A/C cg00495681 chr13:53174319 NA 0.51 4.87 0.4 3.39e-6 Lewy body disease; TGCT cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg02458000 chr6:26745757 NA -0.51 -4.57 -0.38 1.18e-5 Schizophrenia; TGCT cis rs72634258 0.554 rs7556518 chr1:7847846 G/A cg26816564 chr1:7831052 VAMP3 0.95 6.95 0.53 1.88e-10 Inflammatory bowel disease; TGCT cis rs79349575 0.783 rs4794003 chr17:47029904 C/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg05785598 chr3:49045655 WDR6 0.36 4.89 0.4 3e-6 Menarche (age at onset); TGCT cis rs2334880 0.678 rs16973190 chr16:71508501 T/C cg06353428 chr16:71660113 MARVELD3 -1.33 -7.82 -0.57 2.01e-12 Malaria; TGCT cis rs2072499 0.966 rs2842857 chr1:156168736 T/C cg24450063 chr1:156163899 SLC25A44 1.2 18.21 0.85 7.43e-37 Testicular germ cell tumor; TGCT cis rs4665630 0.522 rs75866363 chr2:24046426 G/A cg08063864 chr2:24346004 PFN4;LOC375190 1.18 5.08 0.41 1.35e-6 Hypertension; TGCT cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg23806715 chr17:73775811 H3F3B 0.55 4.55 0.38 1.26e-5 Psoriasis; TGCT cis rs1538970 0.816 rs4633317 chr1:45985157 T/C cg05343316 chr1:45956843 TESK2 0.79 6.48 0.5 1.99e-9 Platelet count; TGCT cis rs4478858 0.652 rs6672056 chr1:31688111 T/C cg00250761 chr1:31883323 NA 0.29 5.03 0.41 1.7e-6 Alcohol dependence; TGCT cis rs76419734 0.558 rs7696836 chr4:106583826 C/T cg24545054 chr4:106630052 GSTCD;INTS12 0.65 4.82 0.4 4.09e-6 Post bronchodilator FEV1; TGCT cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg18252515 chr7:66147081 NA 1.18 7.7 0.57 3.8e-12 Diabetic kidney disease; TGCT cis rs4919694 0.536 rs12414777 chr10:104697781 C/T cg04362960 chr10:104952993 NT5C2 0.68 5.4 0.44 3.21e-7 Arsenic metabolism; TGCT cis rs6754311 0.731 rs309134 chr2:136755684 A/G cg07169764 chr2:136633963 MCM6 -0.69 -6.41 -0.5 2.82e-9 Mosquito bite size; TGCT cis rs9467711 0.523 rs9379853 chr6:26357635 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2730245 0.618 rs859781 chr7:158661758 G/A cg11984989 chr7:158649758 WDR60 1.07 9.74 0.66 5.49e-17 Height; TGCT cis rs7666738 0.830 rs7659593 chr4:98934823 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12510870 0.599 rs7674913 chr4:74449470 G/A cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs9330316 0.632 rs6594037 chr2:110341585 C/G cg25199208 chr2:109402912 CCDC138 -0.41 -4.44 -0.37 1.99e-5 Schizophrenia; TGCT cis rs9467773 1.000 rs6932156 chr6:26571506 T/G cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg02458000 chr6:26745757 NA 0.51 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs17443541 0.507 rs971325 chr2:200450294 A/G cg00055341 chr2:200446845 NA -0.33 -4.61 -0.38 9.81e-6 Intelligence (multi-trait analysis); TGCT cis rs9682041 0.627 rs34392658 chr3:170091584 C/T cg07589077 chr3:170072950 NA 0.26 4.53 0.38 1.36e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7085104 0.700 rs7096183 chr10:104609466 T/C cg04362960 chr10:104952993 NT5C2 0.58 5.14 0.42 1.04e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs1215050 0.755 rs783958 chr4:98893836 A/T cg05340658 chr4:99064831 C4orf37 -0.46 -5.82 -0.46 4.74e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs68170813 0.559 rs76167266 chr7:106900664 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs651907 0.535 rs12631513 chr3:101517476 A/C cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs155076 1.000 rs484365 chr13:21845944 G/T cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 7.13 0.54 7.33e-11 Schizophrenia; TGCT cis rs9611565 0.571 rs7364123 chr22:42216326 A/G cg03806693 chr22:41940476 POLR3H -0.86 -7.93 -0.58 1.09e-12 Vitiligo; TGCT cis rs62380364 0.542 rs2247885 chr5:88047999 T/C cg22951263 chr5:87985283 NA -0.58 -6.12 -0.48 1.12e-8 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.739 rs11222358 chr11:130730497 G/A cg14779329 chr11:130786720 SNX19 0.25 4.44 0.37 1.96e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs7618501 0.722 rs9853458 chr3:49783211 A/C cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs317865 0.867 rs7668729 chr4:16180391 A/C cg04764131 chr4:16228633 TAPT1;FLJ39653 -0.68 -4.53 -0.38 1.35e-5 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs1129187 0.755 rs2296804 chr6:42931261 C/G cg10862848 chr6:42927986 GNMT -0.37 -4.47 -0.37 1.75e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12477438 0.798 rs2309524 chr2:99659510 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs7267979 0.816 rs8115257 chr20:25207931 A/G cg16686733 chr20:25566563 NINL 0.48 4.5 0.37 1.52e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7178424 0.649 rs17271158 chr15:62143664 C/T cg00456672 chr15:62358751 C2CD4A -0.31 -4.47 -0.37 1.75e-5 Height; TGCT cis rs919433 0.617 rs10931793 chr2:198577585 G/A cg00792783 chr2:198669748 PLCL1 -0.55 -5.04 -0.41 1.62e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs208520 0.690 rs2126120 chr6:66742754 A/G cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs1129187 0.935 rs9462859 chr6:42946943 G/A cg09436375 chr6:42928200 GNMT -0.4 -5.13 -0.42 1.06e-6 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs10504390 0.656 rs75002270 chr8:66474587 T/C cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.26e-10 IgG glycosylation; TGCT cis rs3015497 1.000 rs3015495 chr14:51114703 C/T cg04730355 chr14:51134070 SAV1 -0.54 -4.74 -0.39 5.8e-6 Mean platelet volume; TGCT cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs7666738 0.546 rs10026181 chr4:98814118 C/T cg05340658 chr4:99064831 C4orf37 -0.56 -5.96 -0.47 2.4e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9858542 0.537 rs9864406 chr3:49352619 A/G cg08550065 chr3:50336684 HYAL3;NAT6 0.64 4.57 0.38 1.17e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs13401104 0.680 rs72620813 chr2:237146225 C/T cg26422059 chr2:237146110 ASB18 0.57 4.62 0.38 9.62e-6 Educational attainment; TGCT cis rs60843830 1.000 rs62114548 chr2:274672 C/G cg25945732 chr2:264204 ACP1;SH3YL1 0.73 7.33 0.55 2.65e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs12142240 0.698 rs1057535 chr1:46815898 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs228437 0.526 rs2474924 chr6:134907563 A/T cg09872934 chr6:134495829 SGK1 0.61 5.33 0.43 4.57e-7 Melanoma; TGCT cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs7552404 0.690 rs7549863 chr1:76327923 T/C cg22875332 chr1:76189707 ACADM -0.57 -6.14 -0.48 1.05e-8 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs1496653 0.602 rs34928966 chr3:23450757 C/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs4808199 0.947 rs2099333 chr19:19605963 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.15 0.42 9.94e-7 Nonalcoholic fatty liver disease; TGCT trans rs1814175 0.645 rs847635 chr11:49923323 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs11792861 0.851 rs4542004 chr9:111814478 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.47 4.64 0.38 8.84e-6 Menarche (age at onset); TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg23131131 chr22:24373011 LOC391322 -0.83 -9.34 -0.64 5e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4891159 0.790 rs11150953 chr18:74145491 G/A cg24786174 chr18:74118243 ZNF516 -0.54 -7.19 -0.54 5.41e-11 Longevity; TGCT cis rs58799304 0.644 rs11578696 chr1:156056968 A/G cg25208724 chr1:156163844 SLC25A44 0.85 4.79 0.4 4.58e-6 Ischemic stroke; TGCT cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg07424592 chr7:64974309 NA 1.4 8.37 0.6 1.04e-13 Diabetic kidney disease; TGCT cis rs807669 0.548 rs723414 chr22:19185736 G/A cg02655711 chr22:19163373 SLC25A1 0.31 6.38 0.5 3.25e-9 Metabolite levels; TGCT cis rs2836950 0.501 rs2056844 chr21:40670460 G/C cg06238570 chr21:40685208 BRWD1 -0.61 -6.31 -0.49 4.43e-9 Menarche (age at onset); TGCT cis rs2153535 0.580 rs2327053 chr6:8443127 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs244731 0.959 rs6872021 chr5:176610012 G/A cg17509989 chr5:176798049 RGS14 -0.6 -7.32 -0.55 2.69e-11 Urate levels in lean individuals; TGCT cis rs9467711 0.659 rs72844462 chr6:26563864 A/C cg16898833 chr6:26189333 HIST1H4D 1.25 5.86 0.47 3.88e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs7614311 0.681 rs73130565 chr3:63887135 T/C cg22134162 chr3:63841271 THOC7 -0.4 -5.16 -0.42 9.41e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg03264133 chr6:25882463 NA 0.52 4.82 0.4 4.2e-6 Intelligence (multi-trait analysis); TGCT cis rs9486715 1.000 rs2273621 chr6:97058553 A/G cg06623918 chr6:96969491 KIAA0776 -1.11 -14.98 -0.8 1.36e-29 Headache; TGCT cis rs887829 0.569 rs4663963 chr2:234650193 T/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.56 -0.38 1.22e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs950169 0.595 rs11631921 chr15:85143277 G/A cg12863693 chr15:85201151 NMB 0.39 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs10465746 0.725 rs4907188 chr1:84361608 C/T cg10977910 chr1:84465055 TTLL7 0.69 6.73 0.52 5.74e-10 Obesity-related traits; TGCT cis rs11080466 0.964 rs12455464 chr18:10901807 C/T cg02393756 chr18:9912783 VAPA 0.26 4.73 0.39 6.09e-6 Non-small cell lung cancer; TGCT cis rs6918586 0.636 rs198857 chr6:26102417 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.09e-9 Schizophrenia; TGCT cis rs67311347 0.955 rs73080163 chr3:40533061 G/T cg13683864 chr3:40499215 RPL14 -1.17 -11.19 -0.71 1.56e-20 Renal cell carcinoma; TGCT cis rs13394619 0.875 rs9287734 chr2:11724475 A/G cg07314298 chr2:11723111 GREB1 -0.28 -4.95 -0.41 2.32e-6 Endometriosis; TGCT cis rs7804356 0.651 rs11980739 chr7:26818164 A/G cg03456212 chr7:26904342 SKAP2 -0.54 -4.54 -0.38 1.3e-5 Type 1 diabetes; TGCT cis rs875971 1.000 rs937495 chr7:65779798 A/G cg18876405 chr7:65276391 NA -0.32 -4.92 -0.4 2.72e-6 Aortic root size; TGCT cis rs9611519 0.780 rs9611528 chr22:41648502 T/C cg06634786 chr22:41940651 POLR3H -0.54 -4.87 -0.4 3.37e-6 Neuroticism; TGCT cis rs9400467 0.537 rs1150081 chr6:111479016 A/G cg15721981 chr6:111408429 SLC16A10 0.68 4.48 0.37 1.69e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs35883536 0.587 rs2809812 chr1:101032087 G/T cg10298815 chr1:101004474 GPR88 0.24 4.58 0.38 1.12e-5 Monocyte count; TGCT cis rs9341808 0.617 rs9294170 chr6:80814080 A/G cg08355045 chr6:80787529 NA 0.34 6.03 0.48 1.7e-8 Sitting height ratio; TGCT cis rs35883536 0.528 rs1855800 chr1:101030641 G/A cg06223162 chr1:101003688 GPR88 0.43 8.41 0.6 8.23e-14 Monocyte count; TGCT cis rs9311474 0.607 rs4475032 chr3:52560021 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.74 0.52 5.33e-10 Electroencephalogram traits; TGCT cis rs12477438 0.765 rs7571390 chr2:99626593 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.53 -4.56 -0.38 1.21e-5 Chronic sinus infection; TGCT cis rs3796352 0.568 rs11713376 chr3:52958927 A/G cg11137980 chr3:52469226 SEMA3G 0.3 4.8 0.4 4.45e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4819052 0.851 rs10470247 chr21:46659018 T/C cg06618935 chr21:46677482 NA -0.36 -5.71 -0.46 7.76e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs644799 0.662 rs35793328 chr11:95490896 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.78 7.75 0.57 2.9e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7312774 0.609 rs2374655 chr12:107380162 T/C cg16260113 chr12:107380972 MTERFD3 1.58 6.82 0.52 3.48e-10 Severe influenza A (H1N1) infection; TGCT trans rs6089829 0.962 rs4809456 chr20:61660849 C/A cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs13137859 chr4:99050319 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg07061783 chr6:25882402 NA -0.89 -10.69 -0.69 2.63e-19 Urate levels; TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg22166914 chr1:53195759 ZYG11B 0.3 4.85 0.4 3.62e-6 Monocyte count; TGCT cis rs2836950 0.501 rs62223052 chr21:40708702 A/C cg06238570 chr21:40685208 BRWD1 -0.62 -6.26 -0.49 5.66e-9 Menarche (age at onset); TGCT cis rs6964587 1.000 rs36021614 chr7:91717490 C/G cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs4273100 0.646 rs11652784 chr17:19217261 C/T cg03910582 chr17:19030146 GRAPL -0.51 -6.2 -0.49 7.86e-9 Schizophrenia; TGCT cis rs10504229 0.636 rs115738451 chr8:58055133 A/T cg02725872 chr8:58115012 NA -0.39 -4.74 -0.39 5.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs2932538 0.922 rs7551933 chr1:113086706 C/T cg22162597 chr1:113214053 CAPZA1 -0.27 -5.98 -0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1538970 0.924 rs4660851 chr1:45843810 A/T cg05343316 chr1:45956843 TESK2 0.64 5.05 0.41 1.51e-6 Platelet count; TGCT cis rs2836974 0.932 rs2836953 chr21:40617483 G/A cg06238570 chr21:40685208 BRWD1 0.69 6.47 0.5 2.08e-9 Cognitive function; TGCT cis rs72781680 0.898 rs12612492 chr2:24093756 C/T cg08917208 chr2:24149416 ATAD2B 0.82 5.58 0.45 1.43e-7 Lymphocyte counts; TGCT cis rs1056107 0.931 rs10759536 chr9:114991502 C/T cg02332936 chr9:115140584 NA -0.25 -4.45 -0.37 1.89e-5 Colorectal cancer; TGCT cis rs2153535 0.580 rs7755284 chr6:8457479 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg10862848 chr6:42927986 GNMT -0.36 -4.45 -0.37 1.9e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9325144 0.555 rs7955128 chr12:38684121 A/T cg13010199 chr12:38710504 ALG10B 0.53 4.72 0.39 6.36e-6 Morning vs. evening chronotype; TGCT cis rs10193935 0.901 rs2286701 chr2:42555636 T/C cg27598129 chr2:42591480 NA -0.41 -5.68 -0.45 9.25e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.623 rs3780383 chr9:5232409 G/C cg02405213 chr9:5042618 JAK2 -0.69 -7.96 -0.58 9.22e-13 Pediatric autoimmune diseases; TGCT cis rs2544527 0.563 rs6728667 chr2:15904705 G/A cg26669897 chr2:15909070 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs9473924 0.542 rs2817378 chr6:50789197 G/A cg14470998 chr6:50812995 TFAP2B 1.33 7.94 0.58 1.03e-12 Body mass index; TGCT cis rs1008375 0.966 rs4235391 chr4:17696409 A/G cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6088590 0.502 rs6059861 chr20:33068563 A/T cg08999081 chr20:33150536 PIGU 0.29 5.66 0.45 9.97e-8 Coronary artery disease; TGCT cis rs9894429 0.690 rs11869779 chr17:79570067 C/T cg21028142 chr17:79581711 NPLOC4 -0.3 -7.03 -0.53 1.2e-10 Eye color traits; TGCT cis rs68170813 0.521 rs61673847 chr7:106892431 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg07636037 chr3:49044803 WDR6 0.84 8.59 0.61 3.04e-14 Menarche (age at onset); TGCT cis rs4455778 0.659 rs28683492 chr7:49014741 G/A cg26309511 chr7:48887640 NA -0.45 -5.47 -0.44 2.36e-7 Lung cancer in never smokers; TGCT cis rs13256369 0.708 rs11249886 chr8:8562021 T/A cg17143192 chr8:8559678 CLDN23 0.55 5.1 0.42 1.25e-6 Obesity-related traits; TGCT cis rs11696501 0.688 rs6073850 chr20:44301084 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.79 -0.4 4.67e-6 Brain structure; TGCT cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg22166914 chr1:53195759 ZYG11B -0.4 -6.85 -0.52 2.99e-10 Monocyte count; TGCT cis rs9972944 0.756 rs9894010 chr17:63760156 T/G cg07283582 chr17:63770753 CCDC46 -0.26 -5.11 -0.42 1.18e-6 Total body bone mineral density; TGCT cis rs6570726 0.791 rs365747 chr6:145866784 C/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs79387448 0.745 rs1523196 chr2:103163700 T/G cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs1903068 0.719 rs73236106 chr4:55996712 C/T cg09978860 chr4:56023921 NA 0.55 6.09 0.48 1.31e-8 Endometriosis; TGCT cis rs453301 0.686 rs6748 chr8:8890802 C/T cg06636001 chr8:8085503 FLJ10661 -0.66 -5.58 -0.45 1.42e-7 Joint mobility (Beighton score); TGCT cis rs9303401 0.580 rs12946396 chr17:57164195 T/A cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs2074977 0.500 rs10153493 chr19:3447745 C/T cg08380311 chr19:3435252 NFIC -0.74 -6.92 -0.53 2.1e-10 Height; TGCT cis rs6750047 0.573 rs149148 chr2:38318640 G/A cg07380506 chr2:38303506 CYP1B1 0.59 5.47 0.44 2.37e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs13082711 0.595 rs4973762 chr3:27364789 A/T cg02860705 chr3:27208620 NA 0.44 6.65 0.51 8.54e-10 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2742417 1.000 rs2251954 chr3:45731784 A/G cg04837898 chr3:45731254 SACM1L -0.56 -5.92 -0.47 2.89e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7829975 0.714 rs60315134 chr8:8670599 A/G cg06636001 chr8:8085503 FLJ10661 0.61 5.46 0.44 2.47e-7 Mood instability; TGCT cis rs765787 0.530 rs28756676 chr15:45540360 G/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs2997447 0.846 rs12067677 chr1:26411971 C/T cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.16e-5 QRS complex (12-leadsum); TGCT cis rs9858542 0.953 rs7633271 chr3:49555963 T/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs11098499 0.909 rs28632018 chr4:120386730 T/C cg09307838 chr4:120376055 NA 0.68 6.51 0.5 1.66e-9 Corneal astigmatism; TGCT cis rs12908161 0.959 rs12906348 chr15:85329421 A/C cg12863693 chr15:85201151 NMB 0.41 4.86 0.4 3.54e-6 Schizophrenia; TGCT cis rs12477438 0.798 rs6759354 chr2:99632195 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs7772486 0.875 rs10872582 chr6:146373061 G/A cg05347473 chr6:146136440 FBXO30 0.51 4.83 0.4 3.87e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs1864729 1.000 rs1864729 chr8:98282189 G/A cg08679828 chr8:102218111 ZNF706 -0.98 -6.67 -0.51 7.76e-10 Estradiol plasma levels (breast cancer); TGCT cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.92 0.4 2.68e-6 Menopause (age at onset); TGCT cis rs4727027 0.737 rs10278971 chr7:148780659 A/T cg23583168 chr7:148888333 NA -0.67 -8.47 -0.61 6e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1499614 1.000 rs2707840 chr7:66158015 C/T cg18252515 chr7:66147081 NA -1.26 -7.85 -0.58 1.69e-12 Gout; TGCT cis rs7666738 0.830 rs35822567 chr4:98654138 G/A cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.41e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4499344 0.633 rs259251 chr19:33149768 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs3087591 0.887 rs1013946 chr17:29530350 A/C cg24425628 chr17:29625626 OMG;NF1 0.47 7.35 0.55 2.32e-11 Hip circumference; TGCT cis rs6545883 0.895 rs7588814 chr2:61695589 A/T cg15711740 chr2:61764176 XPO1 -0.54 -4.81 -0.4 4.29e-6 Tuberculosis; TGCT cis rs9653442 0.932 rs893245 chr2:100814893 C/T cg22139774 chr2:100720529 AFF3 -0.39 -6.25 -0.49 5.95e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3099143 1.000 rs4886831 chr15:77106801 T/C cg21673338 chr15:77095150 SCAPER 0.51 4.88 0.4 3.17e-6 Recalcitrant atopic dermatitis; TGCT cis rs3096299 0.509 rs4785691 chr16:89597221 A/G cg02187348 chr16:89574699 SPG7 0.68 7.78 0.57 2.39e-12 Multiple myeloma (IgH translocation); TGCT cis rs6964587 1.000 rs6967256 chr7:91643219 G/A cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT trans rs1814175 0.754 rs10839453 chr11:49955815 A/T cg11707556 chr5:10655725 ANKRD33B -0.38 -7.38 -0.55 2e-11 Height; TGCT cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg20607798 chr8:58055168 NA 0.45 4.66 0.39 7.88e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115317002 chr4:119722809 T/C cg14228332 chr4:119757509 SEC24D 1.38 6.91 0.53 2.21e-10 Cannabis dependence symptom count; TGCT cis rs62064224 0.589 rs9904964 chr17:30662832 A/G cg18200150 chr17:30822561 MYO1D -0.4 -4.77 -0.39 5.03e-6 Schizophrenia; TGCT cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg01017244 chr2:74357527 NA 0.43 5.87 0.47 3.8e-8 Gestational age at birth (maternal effect); TGCT cis rs78456975 0.527 rs10184112 chr2:1571112 A/G cg01028140 chr2:1542097 TPO -0.32 -4.99 -0.41 1.97e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT trans rs1973993 0.691 rs1989141 chr1:96898520 C/T cg10631902 chr5:14652156 NA 0.4 10.92 0.7 7.19e-20 Weight; TGCT cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 6.44 0.5 2.38e-9 Schizophrenia; TGCT cis rs1005277 0.579 rs1780133 chr10:38499509 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.06 -0.59 5.59e-13 Extrinsic epigenetic age acceleration; TGCT cis rs919433 0.679 rs1598469 chr2:198515658 T/C cg00792783 chr2:198669748 PLCL1 0.54 4.8 0.4 4.55e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs367615 0.959 rs2201016 chr5:108947287 T/C cg17395555 chr5:108820864 NA 0.3 4.81 0.4 4.38e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7568458 0.811 rs3755015 chr2:85764041 G/A cg17127132 chr2:85788382 GGCX 0.68 6.58 0.51 1.2e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4319547 0.656 rs10734918 chr12:122921512 A/C cg08088222 chr12:122070432 ORAI1 0.26 4.46 0.37 1.84e-5 Body mass index; TGCT cis rs35000415 0.938 rs12531054 chr7:128644251 A/C cg06242719 chr7:129414860 MIR183;MIR96 0.31 4.52 0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs6840360 0.642 rs2709822 chr4:152351500 A/G cg17479576 chr4:152424074 FAM160A1 -0.57 -6.02 -0.48 1.84e-8 Intelligence (multi-trait analysis); TGCT cis rs453301 0.571 rs2929453 chr8:9084341 A/G cg15556689 chr8:8085844 FLJ10661 -0.64 -6.03 -0.48 1.71e-8 Joint mobility (Beighton score); TGCT cis rs1532993 0.518 rs28670002 chr4:98625759 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6879260 1.000 rs7730585 chr5:179733440 T/C cg13944838 chr5:179740914 GFPT2 -0.4 -6.42 -0.5 2.66e-9 Height; TGCT cis rs875971 0.964 rs60193905 chr7:65971260 A/G cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.1e-6 Aortic root size; TGCT cis rs245880 0.740 rs245888 chr7:29190414 C/T cg17163760 chr7:29186267 CPVL -0.44 -5.54 -0.45 1.73e-7 Warfarin maintenance dose; TGCT cis rs1167827 0.680 rs1167796 chr7:75173180 C/T cg04681579 chr7:75027559 TRIM73;TRIM74 0.39 4.5 0.37 1.55e-5 Body mass index;BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1008375 1.000 rs9991307 chr4:17662408 A/G cg16339924 chr4:17578868 LAP3 0.56 4.86 0.4 3.51e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs360798 0.532 rs12994674 chr2:62996645 G/A cg17519650 chr2:63277830 OTX1 -0.56 -4.65 -0.39 8.2e-6 Coronary artery disease; TGCT cis rs68092024 0.704 rs704575 chr3:99486075 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 5.94 0.47 2.64e-8 Cleft lip with or without cleft palate; TGCT cis rs12497850 0.931 rs7623023 chr3:48914238 G/A cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs155076 1.000 rs261427 chr13:21860998 G/A cg11317459 chr13:21872234 NA -1.32 -10.89 -0.7 8.4e-20 White matter hyperintensity burden; TGCT cis rs11098499 0.908 rs11729050 chr4:120300066 T/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs9611519 0.929 rs9611469 chr22:41433319 T/C cg13695892 chr22:41940480 POLR3H -0.53 -4.62 -0.38 9.54e-6 Neuroticism; TGCT cis rs9910055 0.529 rs228749 chr17:42174570 A/G cg19774624 chr17:42201019 HDAC5 0.66 6.02 0.48 1.84e-8 Total body bone mineral density; TGCT cis rs7267979 1.000 rs6050565 chr20:25347563 A/C cg14121845 chr20:25566513 NINL -0.5 -5.49 -0.44 2.13e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs372883 0.554 rs10154065 chr21:30749480 G/C cg24692254 chr21:30365293 RNF160 0.51 4.63 0.38 9.14e-6 Pancreatic cancer; TGCT cis rs9916302 0.904 rs10221223 chr17:37489100 T/G cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs250677 1.000 rs28173 chr5:148423573 C/T cg18129178 chr5:148520854 ABLIM3 -0.43 -6.48 -0.5 1.96e-9 Breast cancer; TGCT cis rs9549260 0.755 rs9549236 chr13:41147158 C/T cg21288729 chr13:41239152 FOXO1 -0.97 -10.34 -0.68 1.9e-18 Red blood cell count; TGCT cis rs116095464 0.558 rs113796397 chr5:246503 A/G cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs7172971 0.701 rs7172081 chr15:42345272 G/A cg05886115 chr15:42349113 NA 0.32 5.1 0.42 1.25e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT trans rs28735056 0.935 rs537962 chr18:77592660 C/G cg05926928 chr17:57297772 GDPD1 0.71 7.61 0.56 6.04e-12 Schizophrenia; TGCT cis rs11112613 0.713 rs73184083 chr12:105952593 T/A cg03607813 chr12:105948248 NA 0.47 5.72 0.46 7.49e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs782590 0.694 rs2627775 chr2:55877113 C/T cg03859395 chr2:55845619 SMEK2 0.77 8.69 0.62 1.75e-14 Metabolic syndrome; TGCT cis rs1577917 0.958 rs1838958 chr6:86563968 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs4689388 0.856 rs3200 chr4:6304878 C/T cg00701064 chr4:6280414 WFS1 0.45 5.89 0.47 3.47e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7666738 0.830 rs13119913 chr4:98977983 G/T cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs114207133 chr4:119755140 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2964802 0.505 rs6897847 chr5:10831632 T/C cg14521931 chr5:10832172 NA -0.27 -4.49 -0.37 1.59e-5 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7246657 0.943 rs35540940 chr19:38008235 G/A cg18154014 chr19:37997991 ZNF793 0.93 6.54 0.51 1.48e-9 Coronary artery calcification; TGCT cis rs6554196 0.644 rs7694444 chr4:55498515 G/T cg02821500 chr4:54931072 CHIC2 0.5 4.94 0.41 2.47e-6 Monocyte count; TGCT cis rs2180341 0.538 rs4392733 chr6:127712603 T/C cg24812749 chr6:127587940 RNF146 0.61 5.39 0.44 3.45e-7 Breast cancer; TGCT cis rs6582630 0.538 rs12305104 chr12:38336353 C/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs7267979 0.932 rs6132848 chr20:25561645 C/T cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7172809 0.643 rs16953967 chr15:77836521 C/T cg22256960 chr15:77711686 NA -0.5 -5.03 -0.41 1.68e-6 Glucose homeostasis traits; TGCT cis rs6752107 1.000 rs2289474 chr2:234181848 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.81 0.4 4.36e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4699052 0.590 rs2138593 chr4:104238721 T/A cg16532752 chr4:104119610 CENPE -0.58 -5.86 -0.47 3.96e-8 Testicular germ cell tumor; TGCT cis rs877426 0.515 rs57506460 chr13:114767789 G/A cg23466769 chr13:114801307 RASA3 0.18 4.54 0.38 1.31e-5 Facial morphology (factor 14, intercanthal width); TGCT cis rs7681440 0.904 rs10004413 chr4:90769479 T/C cg14346243 chr4:90757452 SNCA -0.55 -5.4 -0.44 3.34e-7 Dementia with Lewy bodies; TGCT cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg27286337 chr10:134555280 INPP5A 0.45 5.35 0.43 4.02e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs28595532 0.764 rs56309519 chr4:119754158 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs66573146 0.831 rs56081162 chr4:6989718 C/T cg00086871 chr4:6988644 TBC1D14 0.94 4.62 0.38 9.61e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9486715 0.867 rs9384585 chr6:96875664 C/T cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs1577917 0.958 rs2197648 chr6:86543887 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.47 -0.44 2.33e-7 Response to antipsychotic treatment; TGCT cis rs514406 0.825 rs497535 chr1:53284677 A/G cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs1691799 0.899 rs1183272 chr12:66735421 T/C cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.87e-9 White blood cell count (basophil); TGCT cis rs12142240 0.698 rs17357635 chr1:46808668 G/A cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT trans rs1814175 0.904 rs7924371 chr11:49620595 C/T cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs524023 0.957 rs561193 chr11:64353029 A/G cg07733098 chr11:64478343 NRXN2 -0.3 -4.44 -0.37 1.99e-5 Urate levels in obese individuals; TGCT cis rs7769051 0.522 rs10457596 chr6:133169974 T/G cg22852734 chr6:133119734 C6orf192 1.15 5.47 0.44 2.39e-7 Type 2 diabetes nephropathy; TGCT cis rs921968 0.643 rs526134 chr2:219402371 G/A cg02176678 chr2:219576539 TTLL4 0.44 6.34 0.49 3.92e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.3 0.55 3.02e-11 Prudent dietary pattern; TGCT cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg06112835 chr11:68658793 MRPL21 0.46 7.65 0.57 4.92e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11190604 0.767 rs79106148 chr10:102184732 G/A cg16342193 chr10:102329863 NA -0.4 -5.02 -0.41 1.74e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs72615157 0.634 rs11762932 chr7:99792666 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 0.62 5.1 0.42 1.22e-6 Lung function (FEV1/FVC); TGCT cis rs2050392 0.517 rs302423 chr10:30772513 A/G cg13289132 chr10:30722225 MAP3K8 -0.38 -4.48 -0.37 1.71e-5 Inflammatory bowel disease; TGCT trans rs2727020 0.681 rs1976901 chr11:49378697 T/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.33 -0.6 1.3e-13 Coronary artery disease; TGCT cis rs9467711 0.790 rs35400317 chr6:26593275 C/T cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs6546537 0.550 rs4241252 chr2:69777065 C/A cg10773587 chr2:69614142 GFPT1 -0.69 -6.26 -0.49 5.87e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs7769051 0.614 rs6912936 chr6:133102664 A/G cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg08280861 chr8:58055591 NA 0.36 4.93 0.4 2.61e-6 Developmental language disorder (linguistic errors); TGCT trans rs208520 0.954 rs72884027 chr6:66995044 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.84 7.59 0.56 6.69e-12 Exhaled nitric oxide output; TGCT cis rs62103177 0.525 rs9949598 chr18:77753037 G/A cg07235805 chr18:78004237 PARD6G -0.46 -4.61 -0.38 1e-5 Opioid sensitivity; TGCT cis rs1372520 0.577 rs2737021 chr4:90739992 T/A cg01966878 chr4:90757139 SNCA -0.31 -4.76 -0.39 5.27e-6 Neuroticism; TGCT cis rs9300255 0.537 rs1618679 chr12:123650714 A/G cg00376283 chr12:123451042 ABCB9 0.72 5.55 0.45 1.65e-7 Neutrophil percentage of white cells; TGCT cis rs1878931 0.501 rs4785934 chr16:3419934 G/T cg22508957 chr16:3507546 NAT15 -0.38 -4.98 -0.41 2.1e-6 Body mass index (adult); TGCT trans rs9354352 0.967 rs9354351 chr6:66696271 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.72 7.89 0.58 1.33e-12 Initial pursuit acceleration in psychotic disorders; TGCT cis rs950776 0.518 rs12914694 chr15:78814444 G/A cg06917634 chr15:78832804 PSMA4 0.96 9.71 0.66 6.43e-17 Sudden cardiac arrest; TGCT cis rs35160687 0.901 rs10200186 chr2:86527423 C/T cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.48e-7 Night sleep phenotypes; TGCT cis rs6912958 0.781 rs3918467 chr6:88180388 C/G cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs3733589 0.590 rs12499734 chr4:10051761 A/G cg02734326 chr4:10020555 SLC2A9 1.03 5.02 0.41 1.75e-6 Renal overload gout; TGCT cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg13866156 chr1:1669148 SLC35E2 -0.24 -5.87 -0.47 3.74e-8 Body mass index; TGCT cis rs9303401 0.614 rs56284918 chr17:57178838 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs10779751 0.959 rs2092642 chr1:11317320 C/T cg08854313 chr1:11322531 MTOR 0.94 10.5 0.69 7.65e-19 Body mass index; TGCT cis rs56399783 0.901 rs73047387 chr7:2774125 G/A cg19731401 chr7:2775893 GNA12 0.36 5.07 0.41 1.4e-6 Childhood ear infection; TGCT cis rs4285028 0.948 rs34478505 chr3:121694071 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs5769707 0.967 rs17182154 chr22:49990470 A/G cg20744362 chr22:50050164 C22orf34 0.27 4.57 0.38 1.16e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs614226 1.000 rs7174 chr12:121017171 A/G cg10072921 chr12:121022843 NA -0.43 -4.59 -0.38 1.08e-5 Type 1 diabetes nephropathy; TGCT cis rs1555895 0.576 rs752375 chr10:863329 C/T cg02193355 chr10:851439 NA 0.21 4.9 0.4 2.94e-6 Survival in rectal cancer; TGCT cis rs1997103 0.906 rs2177806 chr7:55402609 A/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7666738 0.830 rs17027216 chr4:99009152 G/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 0.802 rs208516 chr6:66946119 T/C cg07460842 chr6:66804631 NA -0.9 -9.15 -0.63 1.45e-15 Exhaled nitric oxide output; TGCT cis rs2354432 0.943 rs6660219 chr1:146691404 A/T cg25205988 chr1:146714368 CHD1L 1.32 7.66 0.57 4.54e-12 Mitochondrial DNA levels; TGCT cis rs4727027 0.651 rs12704068 chr7:148856153 T/C cg23583168 chr7:148888333 NA -0.69 -7.8 -0.57 2.21e-12 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs231513 0.556 rs7221263 chr17:42011695 A/G cg26893861 chr17:41843967 DUSP3 0.58 4.51 0.38 1.5e-5 Cognitive function; TGCT cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg06108461 chr20:60628389 TAF4 -0.36 -4.52 -0.38 1.4e-5 Obesity-related traits; TGCT cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg06112835 chr11:68658793 MRPL21 0.47 7.96 0.58 9.28e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs514406 0.800 rs4926930 chr1:53217335 A/G cg16325326 chr1:53192061 ZYG11B -0.74 -9.11 -0.63 1.79e-15 Monocyte count; TGCT cis rs42648 0.693 rs2106274 chr7:89880548 C/T cg25739043 chr7:89950458 NA -0.54 -5.04 -0.41 1.61e-6 Homocysteine levels; TGCT cis rs7552404 0.727 rs5745427 chr1:76332637 C/A cg10523679 chr1:76189770 ACADM -0.67 -6.27 -0.49 5.47e-9 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs6948404 0.737 rs73344647 chr7:36623259 A/C cg00810939 chr1:24463749 IL22RA1 0.68 7.04 0.53 1.17e-10 HIV-1 viral setpoint; TGCT cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg11890956 chr21:40555474 PSMG1 -0.72 -6.41 -0.5 2.76e-9 Cognitive function; TGCT cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg05368731 chr17:41323189 NBR1 1.15 13.14 0.76 2.96e-25 Menopause (age at onset); TGCT cis rs3924048 0.574 rs61776783 chr1:12612657 T/C cg00291366 chr1:12616550 NA 0.33 4.93 0.4 2.6e-6 Optic cup area; TGCT cis rs2239547 0.657 rs13072536 chr3:52861211 A/T cg10802521 chr3:52805072 NEK4 -0.62 -5.85 -0.47 4.1e-8 Schizophrenia; TGCT cis rs12681288 0.782 rs2600500 chr8:1029031 G/C cg04851639 chr8:1020857 NA -0.34 -6.11 -0.48 1.18e-8 Schizophrenia; TGCT cis rs4409675 0.576 rs2815707 chr1:28238880 T/C cg23691781 chr1:28212827 C1orf38 0.26 5.44 0.44 2.76e-7 Corneal astigmatism; TGCT cis rs2075371 0.863 rs1646638 chr7:134008706 T/C cg11752832 chr7:134001865 SLC35B4 0.79 7.31 0.55 2.89e-11 Mean platelet volume; TGCT trans rs629535 0.767 rs72654073 chr8:70081231 G/A cg21567404 chr3:27674614 NA -0.57 -8.99 -0.63 3.38e-15 Dupuytren's disease; TGCT cis rs13242816 0.881 rs12672038 chr7:116187106 G/A cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs986417 0.901 rs10483726 chr14:61039476 A/G cg18240143 chr14:60952599 C14orf39 0.83 4.52 0.38 1.41e-5 Gut microbiota (bacterial taxa); TGCT cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.85 8.63 0.61 2.42e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 0.690 rs12209753 chr6:66703951 A/G cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs78456975 1.000 rs78456975 chr2:1554190 T/G cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs875971 0.660 rs801217 chr7:66010577 C/T cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg13695892 chr22:41940480 POLR3H 0.92 9.06 0.63 2.36e-15 Vitiligo; TGCT cis rs2836974 0.965 rs8134733 chr21:40683459 C/T cg11890956 chr21:40555474 PSMG1 1.12 11.29 0.71 9.26e-21 Cognitive function; TGCT cis rs2204008 0.840 rs7136347 chr12:38453531 G/A cg13010199 chr12:38710504 ALG10B 0.64 5.09 0.42 1.27e-6 Bladder cancer; TGCT trans rs1005277 0.579 rs1740735 chr10:38497777 A/C cg17830980 chr10:43048298 ZNF37B -0.8 -10.01 -0.67 1.19e-17 Extrinsic epigenetic age acceleration; TGCT cis rs2882667 0.931 rs10074461 chr5:138319815 G/T cg04439458 chr5:138467593 SIL1 -0.3 -4.71 -0.39 6.62e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9902453 0.904 rs4567782 chr17:28268800 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.26 0.6 1.9e-13 Coffee consumption (cups per day); TGCT cis rs4654899 0.758 rs6426665 chr1:21382205 T/C cg01072550 chr1:21505969 NA -0.57 -9.39 -0.64 3.77e-16 Superior frontal gyrus grey matter volume; TGCT cis rs9682041 0.740 rs2111826 chr3:170140846 A/G cg11886554 chr3:170076028 SKIL 0.93 6.25 0.49 5.93e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs6490294 0.659 rs642898 chr12:112141233 A/G cg10833066 chr12:111807467 FAM109A 0.31 4.88 0.4 3.25e-6 Mean platelet volume; TGCT cis rs9611565 0.546 rs5758431 chr22:42109917 A/G cg13695892 chr22:41940480 POLR3H 0.89 9.04 0.63 2.55e-15 Vitiligo; TGCT cis rs1008375 1.000 rs10939740 chr4:17617490 T/C cg10189774 chr4:17578691 LAP3 0.58 5.05 0.41 1.57e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2404602 0.716 rs7164060 chr15:76707694 T/C cg26408565 chr15:76604113 ETFA -0.42 -5.43 -0.44 2.8e-7 Blood metabolite levels; TGCT cis rs4711350 1.000 rs2395447 chr6:33743174 T/C cg18005901 chr6:33739558 LEMD2 -0.55 -5.91 -0.47 3.13e-8 Schizophrenia; TGCT cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.85 -9.06 -0.63 2.37e-15 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.520 rs2969379 chr2:99776686 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.9 9.33 0.64 5.15e-16 Chronic sinus infection; TGCT cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg05025164 chr4:1340916 KIAA1530 0.69 5.7 0.46 8.34e-8 Longevity; TGCT cis rs6500602 0.701 rs6500614 chr16:4573938 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 7.58 0.56 7.17e-12 Schizophrenia; TGCT trans rs6089829 0.962 rs6122350 chr20:61664617 A/G cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.547 rs377808 chr1:53190359 T/G cg24675658 chr1:53192096 ZYG11B -0.86 -11.02 -0.7 4.2e-20 Monocyte count; TGCT cis rs7582180 0.629 rs11694642 chr2:100957813 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs7715806 0.500 rs17563700 chr5:74986045 A/G cg19683494 chr5:74908142 NA 0.57 4.93 0.4 2.57e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs6591182 0.504 rs7116712 chr11:65372518 A/G cg27068330 chr11:65405492 SIPA1 -0.95 -10.67 -0.69 3.04e-19 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs7826238 0.653 rs2979202 chr8:8344127 T/C cg08975724 chr8:8085496 FLJ10661 0.57 5.49 0.44 2.14e-7 Systolic blood pressure; TGCT cis rs7412746 0.611 rs1889740 chr1:150799755 C/T cg09365446 chr1:150670422 GOLPH3L 0.32 4.55 0.38 1.25e-5 Melanoma; TGCT cis rs612683 0.664 rs6702766 chr1:100997635 A/G cg06223162 chr1:101003688 GPR88 -0.31 -5.18 -0.42 8.71e-7 Breast cancer; TGCT trans rs877282 0.947 rs7923867 chr10:768094 G/A cg22713356 chr15:30763199 NA 1.19 9.85 0.66 2.99e-17 Uric acid levels; TGCT cis rs11719291 0.584 rs13080725 chr3:49076092 G/A cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 Cognitive function; TGCT cis rs4325129 1.000 rs61821536 chr1:159461308 C/T cg07417683 chr1:159440267 NA -0.45 -4.63 -0.38 9.16e-6 Obesity-related traits; TGCT cis rs9926296 0.744 rs154656 chr16:89708003 T/A cg26513180 chr16:89883248 FANCA -0.6 -5.7 -0.46 8.2e-8 Vitiligo; TGCT cis rs7698623 0.850 rs6532020 chr4:88768928 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs4642101 0.765 rs6791647 chr3:12826425 C/T cg05775895 chr3:12838266 CAND2 -0.8 -9.14 -0.63 1.52e-15 QRS complex (12-leadsum); TGCT trans rs114540395 0.858 rs78446856 chr10:103119815 T/A cg10198749 chr1:39920707 MACF1 0.52 7.12 0.54 7.77e-11 Schizophrenia; TGCT cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg03303774 chr4:1407052 NA 0.32 4.9 0.4 2.9e-6 Obesity-related traits; TGCT cis rs67460515 0.926 rs11715591 chr3:161043137 C/T cg03342759 chr3:160939853 NMD3 -0.51 -5.42 -0.44 2.98e-7 Parkinson's disease; TGCT cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg17971929 chr21:40555470 PSMG1 -0.7 -6.66 -0.51 7.99e-10 Cognitive function; TGCT cis rs7943191 0.768 rs34065644 chr11:62371938 C/T cg22862634 chr11:62369728 EML3;MTA2 0.6 6.0 0.47 2.04e-8 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs6089829 0.926 rs6011552 chr20:61667894 T/C cg03213289 chr20:61660250 NA 0.66 9.28 0.64 6.93e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7027203 0.797 rs7870672 chr9:96606693 A/C cg14396892 chr9:96623032 NA -0.26 -5.46 -0.44 2.51e-7 DNA methylation (variation); TGCT cis rs11792861 0.855 rs72607165 chr9:111814498 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.52 0.38 1.44e-5 Menarche (age at onset); TGCT cis rs1692580 0.807 rs10910036 chr1:2183754 C/G cg24578937 chr1:2090814 PRKCZ 0.2 4.56 0.38 1.22e-5 Coronary artery disease; TGCT cis rs769267 0.930 rs2099334 chr19:19578450 A/G cg08509172 chr19:19383838 TM6SF2 -0.35 -4.6 -0.38 1.02e-5 Tonsillectomy; TGCT cis rs9346649 0.591 rs1873338 chr6:168492087 T/C cg02770688 chr6:168491649 NA 0.34 6.06 0.48 1.48e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs7246657 0.943 rs1035479 chr19:37893300 G/T cg18154014 chr19:37997991 ZNF793 -0.73 -5.38 -0.44 3.53e-7 Coronary artery calcification; TGCT trans rs4332037 0.826 rs4721188 chr7:1953615 G/A cg25206134 chr2:45395956 NA -1.06 -9.11 -0.63 1.78e-15 Bipolar disorder; TGCT cis rs3935685 0.874 rs35761651 chr15:78003069 G/T cg25212270 chr15:78015279 NA 0.27 5.66 0.45 9.87e-8 Intelligence (multi-trait analysis); TGCT cis rs1536827 0.841 rs10857733 chr10:135332803 G/A cg12448312 chr10:135032219 KNDC1 -0.45 -4.76 -0.39 5.27e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs514406 0.621 rs2003250 chr1:53196666 T/C cg08859206 chr1:53392774 SCP2 0.34 4.82 0.4 4.1e-6 Monocyte count; TGCT cis rs9910055 0.530 rs2269907 chr17:42294215 G/A cg13607699 chr17:42295918 UBTF 0.96 11.07 0.7 3.21e-20 Total body bone mineral density; TGCT cis rs11190604 1.000 rs2489050 chr10:102350898 T/A cg16342193 chr10:102329863 NA -0.43 -5.43 -0.44 2.79e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7772486 0.754 rs6570703 chr6:145957052 C/T cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7582180 0.629 rs13025184 chr2:100944842 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs9427116 0.502 rs9426829 chr1:154592201 T/C cg17218026 chr1:154582156 ADAR 0.31 7.83 0.58 1.89e-12 Blood protein levels; TGCT cis rs11711311 1.000 rs2603793 chr3:113496418 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs17270561 0.525 rs12201678 chr6:25978993 C/T cg17691542 chr6:26056736 HIST1H1C 1.02 7.17 0.54 5.89e-11 Iron status biomarkers; TGCT cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs9969804 0.747 rs7021624 chr9:95531220 C/G cg13940029 chr9:95239186 CENPP;ASPN -0.17 -4.54 -0.38 1.29e-5 Height; TGCT cis rs12220238 0.915 rs1908334 chr10:75991721 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7681440 0.869 rs7680557 chr4:90763360 C/A cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.82e-8 Dementia with Lewy bodies; TGCT cis rs28595532 0.920 rs115006522 chr4:119732499 A/G cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs8056742 0.730 rs11649284 chr16:85099251 C/T cg00229868 chr16:85520891 NA -0.32 -4.66 -0.39 8.11e-6 Amyotrophic lateral sclerosis; TGCT cis rs2242194 0.844 rs11264295 chr1:154987526 C/T cg09359103 chr1:154839909 KCNN3 -0.47 -6.53 -0.51 1.51e-9 Schizophrenia; TGCT cis rs4595586 1.000 rs4384412 chr12:39218113 T/C cg10518543 chr12:38710700 ALG10B -0.49 -4.93 -0.4 2.59e-6 Morning vs. evening chronotype; TGCT cis rs514406 0.830 rs533935 chr1:53308807 T/C cg08736216 chr1:53307985 ZYG11A -0.27 -5.04 -0.41 1.64e-6 Monocyte count; TGCT cis rs8013055 0.846 rs10151805 chr14:105974781 T/C cg23356831 chr14:105996513 TMEM121 0.41 6.33 0.49 4.01e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs2797160 1.000 rs6904992 chr6:126016003 G/A cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs10972341 0.904 rs10972353 chr9:35151594 A/T cg00812861 chr9:35114699 KIAA1539 0.33 5.06 0.41 1.44e-6 Weight; TGCT cis rs644799 0.932 rs523934 chr11:95641775 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.77 9.09 0.63 2.04e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs17221829 0.733 rs10830337 chr11:89407049 C/T cg02982614 chr11:89391479 FOLH1B -0.27 -4.56 -0.38 1.19e-5 Anxiety in major depressive disorder; TGCT cis rs9653442 0.527 rs4850923 chr2:100782256 A/C cg07810366 chr2:100720526 AFF3 -0.34 -4.96 -0.41 2.27e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg12310025 chr6:25882481 NA -0.66 -5.95 -0.47 2.57e-8 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.632 rs7849717 chr9:5170080 G/A cg02405213 chr9:5042618 JAK2 -0.72 -9.46 -0.65 2.63e-16 Pediatric autoimmune diseases; TGCT cis rs425277 0.583 rs1467217 chr1:2045165 G/A cg03732007 chr1:2071316 PRKCZ -0.26 -5.89 -0.47 3.45e-8 Height; TGCT cis rs10479542 1.000 rs10479542 chr5:178981241 T/A cg00080972 chr5:178986291 RUFY1 0.46 5.38 0.44 3.55e-7 Lung cancer; TGCT cis rs906628 0.541 rs113946880 chr11:134706712 C/T cg25999867 chr11:134145940 GLB1L3 0.87 4.54 0.38 1.33e-5 Tooth agenesis (mandibular third molar); TGCT cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg17554472 chr22:41940697 POLR3H 0.47 5.04 0.41 1.63e-6 Vitiligo; TGCT cis rs3091242 1.000 rs646867 chr1:25709258 A/C cg09222892 chr1:25734099 RHCE -0.44 -7.12 -0.54 7.52e-11 Erythrocyte sedimentation rate; TGCT cis rs10256972 0.721 rs10435145 chr7:1065988 C/T cg09177884 chr7:1199841 ZFAND2A -0.5 -4.7 -0.39 6.84e-6 Longevity;Endometriosis; TGCT cis rs11098499 0.909 rs10017335 chr4:120381523 C/G cg09307838 chr4:120376055 NA -0.7 -6.43 -0.5 2.56e-9 Corneal astigmatism; TGCT cis rs1008375 1.000 rs1121090 chr4:17676437 C/G cg18681998 chr4:17616180 MED28 0.89 10.2 0.68 4.06e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4746818 1.000 rs4342912 chr10:70959282 T/C cg11621586 chr10:70884670 VPS26A 1.21 10.5 0.69 7.7e-19 Left atrial antero-posterior diameter; TGCT cis rs4478858 0.735 rs11576603 chr1:31774031 C/T cg07478791 chr1:31886160 SERINC2 -0.48 -4.61 -0.38 1e-5 Alcohol dependence; TGCT cis rs7917772 0.582 rs4917975 chr10:104358407 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs763014 0.865 rs4006748 chr16:632225 T/C cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT trans rs941408 0.963 rs2537855 chr19:2806574 A/G cg19676328 chr12:49525230 TUBA1B -0.85 -7.52 -0.56 9.73e-12 Total cholesterol levels; TGCT trans rs7824557 0.547 rs4512344 chr8:11078781 A/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.0 -0.53 1.44e-10 Retinal vascular caliber; TGCT cis rs6840360 0.967 rs6841204 chr4:152598603 C/T cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs769267 0.859 rs2916076 chr19:19545990 T/C cg03709012 chr19:19516395 GATAD2A 0.75 6.51 0.5 1.71e-9 Tonsillectomy; TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg00024416 chr22:24240387 NA -0.38 -6.58 -0.51 1.16e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg05215272 chr17:6899095 ALOX12 0.53 6.55 0.51 1.37e-9 Tonsillectomy; TGCT cis rs2231884 0.697 rs11227332 chr11:65623739 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.68 5.8 0.46 5.25e-8 Inflammatory bowel disease; TGCT cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg18765753 chr7:1198926 ZFAND2A -0.48 -5.65 -0.45 1.06e-7 Longevity;Endometriosis; TGCT cis rs2797160 1.000 rs1739352 chr6:126005310 T/C cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs6582630 0.519 rs8189561 chr12:38296178 G/A cg13010199 chr12:38710504 ALG10B 0.57 4.45 0.37 1.89e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs763014 1.000 rs763014 chr16:675680 T/C cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.15e-6 Height; TGCT cis rs4975709 0.589 rs4975747 chr5:1862836 G/A cg14773178 chr5:1868261 NA 0.33 5.79 0.46 5.47e-8 Cardiovascular disease risk factors; TGCT cis rs826838 0.620 rs11614695 chr12:39331847 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.28 0.55 3.35e-11 Heart rate; TGCT cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs66887589 0.616 rs1052633 chr4:120215314 A/G cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.16e-5 Diastolic blood pressure; TGCT cis rs17102423 0.594 rs1953232 chr14:65570386 A/C cg11161011 chr14:65562177 MAX 0.47 6.48 0.5 1.94e-9 Obesity-related traits; TGCT cis rs7226408 0.790 rs9946701 chr18:34340486 C/G cg06757138 chr18:34340585 FHOD3 0.3 5.02 0.41 1.75e-6 Obesity-related traits; TGCT cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg13695892 chr22:41940480 POLR3H 0.93 9.1 0.63 1.91e-15 Vitiligo; TGCT cis rs78487399 0.808 rs28700209 chr2:43667465 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs67311347 0.544 rs9868700 chr3:40345408 G/A cg13683864 chr3:40499215 RPL14 -0.79 -7.57 -0.56 7.26e-12 Renal cell carcinoma; TGCT cis rs16867321 0.950 rs1919148 chr2:181501758 G/A cg23363182 chr2:181467187 NA -0.4 -5.7 -0.46 8.41e-8 Obesity; TGCT cis rs9814567 1.000 rs6769885 chr3:134286913 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.45 -0.6 6.55e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs72634258 0.519 rs35267144 chr1:7934258 G/A cg26816564 chr1:7831052 VAMP3 0.64 4.9 0.4 2.97e-6 Inflammatory bowel disease; TGCT cis rs12142240 0.698 rs72886911 chr1:46814352 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs2836974 0.666 rs4624474 chr21:40686327 T/C cg17971929 chr21:40555470 PSMG1 -0.7 -6.32 -0.49 4.38e-9 Cognitive function; TGCT cis rs72615157 0.613 rs56089143 chr7:99819844 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.64 5.04 0.41 1.63e-6 Lung function (FEV1/FVC); TGCT cis rs11252926 0.537 rs4881255 chr10:453638 T/C cg20256804 chr10:444983 DIP2C -0.21 -4.45 -0.37 1.88e-5 Psychosis in Alzheimer's disease; TGCT cis rs523522 0.962 rs1050187 chr12:120902111 A/G cg27279351 chr12:120934652 DYNLL1 -0.76 -6.58 -0.51 1.19e-9 High light scatter reticulocyte count; TGCT cis rs514406 0.548 rs6670871 chr1:53212082 A/C cg22166914 chr1:53195759 ZYG11B -0.5 -9.19 -0.64 1.16e-15 Monocyte count; TGCT cis rs7647973 1.000 rs2177268 chr3:49439725 A/T cg05785598 chr3:49045655 WDR6 -0.4 -4.67 -0.39 7.57e-6 Menarche (age at onset); TGCT cis rs9303401 0.592 rs12936771 chr17:56725052 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs2013441 1.000 rs2703794 chr17:20073338 T/C cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs11209185 0.672 rs1926278 chr1:68453859 C/T cg22082780 chr1:68452167 NA 0.29 4.98 0.41 2.09e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs6570726 0.967 rs9403707 chr6:145800010 A/G cg23711669 chr6:146136114 FBXO30 0.62 5.84 0.46 4.3e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg26531700 chr6:26746687 NA 0.52 4.85 0.4 3.65e-6 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg09033563 chr22:24373618 LOC391322 -0.47 -4.49 -0.37 1.59e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12421382 0.507 rs10890995 chr11:109327622 A/G cg16359550 chr11:109292809 C11orf87 -0.72 -8.08 -0.59 4.95e-13 Schizophrenia; TGCT cis rs2242116 0.796 rs9852082 chr3:46972377 T/C cg02527881 chr3:46936655 PTH1R -0.33 -5.89 -0.47 3.34e-8 Birth weight; TGCT cis rs2455799 0.613 rs7633542 chr3:15816326 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.76e-6 Mean platelet volume; TGCT cis rs7949030 0.653 rs2516634 chr11:62367186 G/A cg22862634 chr11:62369728 EML3;MTA2 -0.7 -9.07 -0.63 2.22e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6582630 0.555 rs10748382 chr12:38504529 C/T cg13010199 chr12:38710504 ALG10B 0.66 5.65 0.45 1.06e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs4654899 1.000 rs6702110 chr1:21515906 A/G cg01072550 chr1:21505969 NA -0.51 -8.23 -0.59 2.15e-13 Superior frontal gyrus grey matter volume; TGCT cis rs4629710 0.563 rs9483238 chr6:131567196 A/T cg12606694 chr6:131520996 AKAP7 0.39 4.61 0.38 9.76e-6 Multiple myeloma (IgH translocation); TGCT cis rs1215050 0.791 rs984940 chr4:98811756 T/A cg05340658 chr4:99064831 C4orf37 0.44 5.57 0.45 1.53e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs57994353 0.861 rs34302850 chr9:139327064 A/G cg13741927 chr9:139327495 INPP5E -0.27 -6.2 -0.49 7.7e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs137887 0.817 rs137888 chr22:50464496 G/A cg17558497 chr22:50464837 TTLL8 0.2 4.56 0.38 1.21e-5 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs68170813 0.652 rs4730250 chr7:107207695 A/G cg02696742 chr7:106810147 HBP1 -0.59 -4.71 -0.39 6.61e-6 Coronary artery disease; TGCT cis rs1153858 1.000 rs2114501 chr15:45670316 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs6089829 0.926 rs1060489 chr20:61665921 C/T cg08045932 chr20:61659980 NA 0.49 9.25 0.64 8.4e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs4595586 0.545 rs11610886 chr12:39390613 C/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs713587 0.626 rs62140636 chr2:25233811 T/C cg01884057 chr2:25150051 NA -0.38 -7.59 -0.56 6.56e-12 Body mass index in non-asthmatics; TGCT cis rs6964587 1.000 rs7805077 chr7:91644553 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs10791097 0.694 rs4264159 chr11:130755784 G/T cg12179176 chr11:130786555 SNX19 0.83 9.92 0.67 1.94e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs61990749 0.597 rs2364584 chr14:78152286 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.62 -0.38 9.57e-6 Fibroblast growth factor basic levels; TGCT cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg06481639 chr22:41940642 POLR3H 0.74 6.58 0.51 1.2e-9 Vitiligo; TGCT cis rs7635838 0.892 rs2880897 chr3:11494544 A/G cg00170343 chr3:11313890 ATG7 0.63 5.54 0.45 1.72e-7 HDL cholesterol; TGCT cis rs7267979 0.844 rs4815413 chr20:25359229 G/T cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs36051895 0.593 rs12340379 chr9:5176352 C/T cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.2e-20 Pediatric autoimmune diseases; TGCT cis rs6570726 1.000 rs404229 chr6:145868200 G/A cg05347473 chr6:146136440 FBXO30 0.5 4.46 0.37 1.82e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10037670 1.000 rs10037670 chr5:153811490 C/T cg21964928 chr5:153872958 NA -0.26 -5.17 -0.42 9.21e-7 Behavioural disinhibition (generation interaction); TGCT cis rs9899728 0.572 rs4365317 chr17:73059820 C/G cg27626185 chr17:73056755 KCTD2 -0.46 -4.49 -0.37 1.59e-5 Alzheimer's disease or small vessel stroke; TGCT cis rs1532993 0.518 rs7442272 chr4:98583775 C/T cg05340658 chr4:99064831 C4orf37 -0.38 -4.49 -0.37 1.58e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs782590 0.764 rs935177 chr2:55826761 C/G cg03859395 chr2:55845619 SMEK2 0.84 10.09 0.67 7.69e-18 Metabolic syndrome; TGCT cis rs9653442 0.564 rs4851253 chr2:100762786 T/G cg22139774 chr2:100720529 AFF3 -0.38 -5.97 -0.47 2.35e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg06634786 chr22:41940651 POLR3H -0.88 -8.48 -0.61 5.74e-14 Vitiligo; TGCT cis rs644799 0.526 rs530914 chr11:95632156 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.49 4.84 0.4 3.82e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7927771 0.864 rs112060627 chr11:47426956 G/A cg10139015 chr11:47448256 PSMC3 0.52 4.44 0.37 1.97e-5 Subjective well-being; TGCT cis rs12893668 0.637 rs12892038 chr14:104068629 G/A cg26031613 chr14:104095156 KLC1 -0.55 -4.64 -0.38 8.81e-6 Reticulocyte count; TGCT trans rs17685 0.712 rs6954569 chr7:75738885 T/A cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg10047753 chr17:41438598 NA 0.96 9.54 0.65 1.61e-16 Menopause (age at onset); TGCT cis rs425277 1.000 rs262651 chr1:2091397 A/G cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs9325144 0.560 rs13377717 chr12:38639474 T/A cg13010199 chr12:38710504 ALG10B -0.51 -4.52 -0.38 1.45e-5 Morning vs. evening chronotype; TGCT cis rs514406 0.861 rs2477741 chr1:53265278 A/G cg22166914 chr1:53195759 ZYG11B -0.42 -7.36 -0.55 2.26e-11 Monocyte count; TGCT cis rs6543140 0.964 rs6543138 chr2:103066132 G/A cg09003973 chr2:102972529 NA 0.56 4.67 0.39 7.86e-6 Blood protein levels; TGCT cis rs11031096 0.563 rs12289940 chr11:4224589 T/A cg18678763 chr11:4115507 RRM1 -0.39 -4.91 -0.4 2.82e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT trans rs6089829 0.890 rs6062775 chr20:61663650 T/C cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2576037 0.583 rs487386 chr18:44377004 A/G cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.79 -0.4 4.61e-6 Personality dimensions; TGCT cis rs7267979 1.000 rs7020 chr20:25278600 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11648796 0.718 rs62032512 chr16:764826 C/T cg27144592 chr16:783916 NARFL 0.39 5.42 0.44 2.92e-7 Height; TGCT cis rs6952808 0.531 rs73039217 chr7:2178731 G/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.17 -0.48 8.79e-9 Bipolar disorder and schizophrenia; TGCT cis rs13108904 0.517 rs13128825 chr4:1334007 G/A cg00684032 chr4:1343700 KIAA1530 0.22 4.73 0.39 5.89e-6 Obesity-related traits; TGCT cis rs5769707 0.521 rs739244 chr22:50060158 A/G cg05373962 chr22:49881684 NA -0.32 -5.42 -0.44 3e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs8180040 1.000 rs1024037 chr3:47318449 C/A cg27129171 chr3:47204927 SETD2 -0.69 -8.17 -0.59 2.94e-13 Colorectal cancer; TGCT cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg08645402 chr16:4508243 NA 0.21 5.03 0.41 1.65e-6 Schizophrenia; TGCT cis rs60154123 0.772 rs701944 chr1:210417098 G/A cg22029157 chr1:209979665 IRF6 0.64 4.52 0.38 1.43e-5 Coronary artery disease; TGCT cis rs12711979 0.584 rs11694096 chr2:3868113 G/A cg17052675 chr2:3827356 NA -0.4 -7.24 -0.54 4.24e-11 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs4319547 1.000 rs7295397 chr12:123116209 C/T cg23029597 chr12:123009494 RSRC2 -0.31 -5.16 -0.42 9.31e-7 Body mass index; TGCT trans rs916888 0.610 rs142167 chr17:44795234 C/T cg10053473 chr17:62856997 LRRC37A3 0.41 7.06 0.54 1.03e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2692947 0.644 rs1724125 chr2:96831355 G/A cg22654517 chr2:96458247 NA 0.23 4.83 0.4 4e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9549367 0.789 rs912012 chr13:113886152 G/A cg00898013 chr13:113819073 PROZ -0.4 -4.88 -0.4 3.18e-6 Platelet distribution width; TGCT cis rs9910055 0.762 rs2631299 chr17:42219773 G/T cg13607699 chr17:42295918 UBTF 0.82 7.53 0.56 9.29e-12 Total body bone mineral density; TGCT cis rs2730260 0.537 rs56023468 chr7:158875329 T/C cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs10484885 0.715 rs2585013 chr6:90553402 T/G cg13799429 chr6:90582589 CASP8AP2 -0.55 -6.6 -0.51 1.09e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg09177884 chr7:1199841 ZFAND2A -0.6 -6.13 -0.48 1.09e-8 Longevity;Endometriosis; TGCT cis rs7819412 0.806 rs2409689 chr8:10932868 A/G cg21775007 chr8:11205619 TDH -0.5 -4.62 -0.38 9.28e-6 Triglycerides; TGCT cis rs3796352 0.892 rs11718388 chr3:53076415 G/A cg15956490 chr3:53032818 SFMBT1 0.59 6.75 0.52 5.19e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs9303401 0.580 rs2013166 chr17:56637630 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7917772 0.560 rs35095897 chr10:104377759 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.46 -0.44 2.51e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2742417 1.000 rs2673047 chr3:45743113 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs4862750 0.881 rs6813866 chr4:187872161 T/G cg10295955 chr4:187884368 NA -0.93 -12.52 -0.75 9.29e-24 Lobe attachment (rater-scored or self-reported); TGCT cis rs9894429 0.789 rs7219915 chr17:79591813 C/T cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs4769475 0.957 rs7327409 chr13:26730668 A/G cg19000612 chr13:26506281 ATP8A2 0.3 4.48 0.37 1.66e-5 Response to Homoharringtonine (cytotoxicity); TGCT cis rs10256972 0.567 rs2960850 chr7:1211649 A/G cg09177884 chr7:1199841 ZFAND2A -0.59 -5.58 -0.45 1.42e-7 Longevity;Endometriosis; TGCT cis rs9611519 0.761 rs35445172 chr22:41660301 G/A cg06634786 chr22:41940651 POLR3H -0.55 -4.98 -0.41 2.04e-6 Neuroticism; TGCT cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs78545713 1.000 rs114970164 chr6:26241993 G/C cg12260798 chr6:26240519 HIST1H4F -0.58 -4.89 -0.4 3.06e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs3796352 1.000 rs34933390 chr3:53006265 T/G cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9467711 0.539 rs34436535 chr6:26370365 G/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs916888 0.647 rs199523 chr17:44848517 C/A cg01570182 chr17:44337453 NA -0.84 -8.15 -0.59 3.41e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs875971 0.540 rs1723268 chr7:65473080 A/C cg00343986 chr7:65444356 GUSB 0.25 5.81 0.46 4.88e-8 Aortic root size; TGCT cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7246657 0.882 rs13345148 chr19:37819631 A/G cg18154014 chr19:37997991 ZNF793 0.74 5.08 0.42 1.34e-6 Coronary artery calcification; TGCT cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs6866344 0.570 rs56236920 chr5:178144617 C/T cg10224037 chr5:178157518 ZNF354A 0.98 9.34 0.64 5.07e-16 Neutrophil percentage of white cells; TGCT cis rs981844 0.775 rs55986083 chr4:154765640 A/C cg14289246 chr4:154710475 SFRP2 1.0 8.87 0.62 6.69e-15 Response to statins (LDL cholesterol change); TGCT cis rs1865760 0.566 rs2032443 chr6:26046802 A/G cg17042849 chr6:26104293 HIST1H4C -0.6 -5.17 -0.42 8.99e-7 Height; TGCT cis rs769267 0.930 rs2301784 chr19:19390749 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs10858047 0.883 rs761755 chr1:115222434 G/A cg12756093 chr1:115239321 AMPD1 -0.49 -5.17 -0.42 9.05e-7 Autism; TGCT cis rs12765878 0.541 rs7091346 chr10:105608824 C/T cg11005552 chr10:105648138 OBFC1 -0.38 -6.06 -0.48 1.49e-8 Coronary artery disease; TGCT cis rs2404602 0.716 rs12441550 chr15:76863682 A/T cg22467129 chr15:76604101 ETFA -0.44 -5.05 -0.41 1.51e-6 Blood metabolite levels; TGCT cis rs763121 0.853 rs2281021 chr22:39064667 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs3008870 1.000 rs3008858 chr1:67390416 G/C cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs4664308 1.000 rs62175517 chr2:160911575 C/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs8177253 1.000 rs8177262 chr3:133480652 A/G cg16414030 chr3:133502952 NA 0.57 8.59 0.61 3.07e-14 Iron status biomarkers; TGCT cis rs10791097 0.667 rs12363163 chr11:130744509 A/G cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs789852 0.867 rs6437391 chr3:194316826 C/T cg18000598 chr3:194342907 TMEM44 -0.76 -5.09 -0.42 1.31e-6 QT interval; TGCT cis rs4285028 0.948 rs1920309 chr3:121665479 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs7586879 0.593 rs6733224 chr2:25130907 C/T cg01884057 chr2:25150051 NA -0.35 -6.86 -0.52 2.97e-10 Body mass index; TGCT cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs1864729 1.000 rs2451113 chr8:98273448 G/A cg08679828 chr8:102218111 ZNF706 -1.07 -7.39 -0.55 1.87e-11 Estradiol plasma levels (breast cancer); TGCT cis rs3818285 0.544 rs9787456 chr10:111711822 A/G cg00817464 chr10:111662876 XPNPEP1 -0.3 -4.87 -0.4 3.4e-6 Superior crus of antihelix expression; TGCT cis rs3806843 0.966 rs2563262 chr5:140137712 C/G cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7927771 0.864 rs3781627 chr11:47441472 T/A cg10139015 chr11:47448256 PSMC3 -0.57 -4.65 -0.39 8.31e-6 Subjective well-being; TGCT cis rs11098499 0.866 rs11098506 chr4:120284971 A/G cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs13191362 0.938 rs59067610 chr6:163030440 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.56 4.64 0.38 8.87e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1865760 1.000 rs2071299 chr6:25914801 G/A cg16482183 chr6:26056742 HIST1H1C 0.52 4.6 0.38 1.04e-5 Height; TGCT cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -5.41 -0.44 3.19e-7 Developmental language disorder (linguistic errors); TGCT cis rs1018836 0.828 rs9297871 chr8:91572731 G/A cg16814680 chr8:91681699 NA -0.75 -7.85 -0.58 1.71e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9633740 0.842 rs1870140 chr10:82246749 A/G cg01528321 chr10:82214614 TSPAN14 0.9 6.44 0.5 2.37e-9 Post bronchodilator FEV1; TGCT cis rs3617 0.573 rs56383738 chr3:52908398 T/C cg11645453 chr3:52864694 ITIH4 -0.28 -5.48 -0.44 2.24e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs11605924 0.792 rs10838524 chr11:45870177 A/G ch.11.939596F chr11:45881766 CRY2 -0.36 -4.52 -0.38 1.43e-5 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs2820292 0.583 rs651103 chr1:201764737 G/T cg07139329 chr1:201708558 NAV1 0.35 4.6 0.38 1.03e-5 Waist circumference;Body mass index (joint analysis main effects and smoking interaction);Body mass index;BMI in non-smokers;BMI (adjusted for smoking behaviour); TGCT cis rs6964587 1.000 rs10225892 chr7:91671020 A/G cg17063962 chr7:91808500 NA 0.88 9.63 0.65 9.8e-17 Breast cancer; TGCT cis rs700651 0.789 rs1978889 chr2:198889366 G/A cg00792783 chr2:198669748 PLCL1 0.59 5.34 0.43 4.33e-7 Intracranial aneurysm; TGCT cis rs4975709 0.589 rs931508 chr5:1861224 C/G cg12288994 chr5:1860383 NA 0.24 4.47 0.37 1.78e-5 Cardiovascular disease risk factors; TGCT trans rs1814175 0.817 rs6486044 chr11:49982718 C/T cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs593982 0.777 rs534414 chr11:65475515 A/G cg08755490 chr11:65554678 OVOL1 1.3 7.59 0.56 6.8e-12 Atopic dermatitis; TGCT cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs2832077 0.527 rs11088095 chr21:30223188 A/T cg24692254 chr21:30365293 RNF160 -0.59 -5.05 -0.41 1.53e-6 Cognitive test performance; TGCT cis rs1729951 0.545 rs1097288 chr3:136693721 C/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs2070433 0.752 rs11700468 chr21:47776391 C/T cg12379764 chr21:47803548 PCNT 0.66 5.61 0.45 1.25e-7 Lymphocyte counts; TGCT cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg04944784 chr2:26401820 FAM59B 0.69 5.74 0.46 6.71e-8 Gut microbiome composition (summer); TGCT cis rs1371867 0.846 rs1788205 chr8:101306546 G/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs826838 0.935 rs4583043 chr12:38645147 T/G cg26384229 chr12:38710491 ALG10B 0.99 9.34 0.64 4.97e-16 Heart rate; TGCT cis rs6062496 0.631 rs6062300 chr20:62303794 G/A cg27236539 chr20:62289627 RTEL1 0.69 6.52 0.51 1.59e-9 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs9914988 0.673 rs12325788 chr17:27080049 G/A cg20469991 chr17:27169893 C17orf63 -0.66 -5.03 -0.41 1.65e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs3812831 0.695 rs6560936 chr13:114945972 C/T cg08824895 chr13:115047677 UPF3A -0.49 -4.74 -0.39 5.83e-6 Schizophrenia; TGCT cis rs2404602 0.735 rs12903874 chr15:76693318 A/T cg22467129 chr15:76604101 ETFA 0.49 5.06 0.41 1.5e-6 Blood metabolite levels; TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg22764044 chr5:178986830 RUFY1 0.5 5.57 0.45 1.49e-7 Lung cancer; TGCT cis rs4455778 0.692 rs7800120 chr7:49012977 C/T cg26309511 chr7:48887640 NA -0.47 -5.84 -0.46 4.38e-8 Lung cancer in never smokers; TGCT cis rs4242434 0.927 rs7843828 chr8:22463623 C/T cg21658235 chr8:22456391 C8orf58 0.43 4.53 0.38 1.36e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs3733585 0.699 rs6852441 chr4:9973744 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.72 -0.52 5.74e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13242816 1.000 rs62468973 chr7:116125834 G/T cg16553024 chr7:116138462 CAV2 -0.43 -4.88 -0.4 3.26e-6 P wave duration; TGCT cis rs1862618 0.671 rs72644088 chr5:56241019 G/A cg12311346 chr5:56204834 C5orf35 0.59 6.35 0.5 3.68e-9 Initial pursuit acceleration; TGCT trans rs11992162 0.548 rs4841631 chr8:11781668 C/T cg15556689 chr8:8085844 FLJ10661 -0.81 -6.99 -0.53 1.48e-10 Monocyte count; TGCT cis rs67311347 0.955 rs1129200 chr3:40532257 T/C cg13409248 chr3:40428643 ENTPD3 0.63 4.92 0.4 2.72e-6 Renal cell carcinoma; TGCT cis rs12711979 0.904 rs12329356 chr2:3868533 G/C cg17052675 chr2:3827356 NA -0.32 -5.85 -0.46 4.12e-8 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg15659132 chr6:26577336 NA 0.87 10.72 0.69 2.19e-19 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg18230493 chr5:56204884 C5orf35 -0.83 -6.76 -0.52 4.9e-10 Initial pursuit acceleration; TGCT cis rs7267979 1.000 rs6115146 chr20:25304507 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.49 -0.61 5.27e-14 Platelet count; TGCT cis rs875971 1.000 rs12533997 chr7:65965377 A/G cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.1e-6 Aortic root size; TGCT cis rs11098499 0.954 rs10518331 chr4:120323595 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7744392 0.557 rs9658100 chr6:35356640 G/T cg06087101 chr6:35551932 FKBP5 -0.61 -4.56 -0.38 1.21e-5 Cataracts in type 2 diabetes; TGCT cis rs79349575 0.783 rs62075838 chr17:46996432 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs3757318 0.686 rs17688135 chr6:151849040 G/A cg18745416 chr6:152011399 ESR1 0.52 4.84 0.4 3.82e-6 Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative);Breast cancer; TGCT cis rs250677 0.652 rs36042 chr5:148439782 G/T cg18129178 chr5:148520854 ABLIM3 -0.42 -5.74 -0.46 6.77e-8 Breast cancer; TGCT cis rs2820315 1.000 rs2132363 chr1:201826482 C/T cg12730843 chr1:201915899 LMOD1 -0.27 -4.8 -0.4 4.44e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs9788682 0.591 rs7170068 chr15:78912943 G/A cg24631222 chr15:78858424 CHRNA5 0.93 6.27 0.49 5.43e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs769267 0.965 rs2315025 chr19:19426609 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs6582630 0.572 rs7315897 chr12:38449081 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs62012628 0.527 rs12438008 chr15:79084680 C/T cg00639195 chr15:79103007 ADAMTS7 0.5 4.68 0.39 7.26e-6 Diastolic blood pressure; TGCT cis rs58904263 1 rs58904263 chr20:30401406 A/AG cg13852791 chr20:30311386 BCL2L1 0.76 5.71 0.46 8.02e-8 Monocyte count; TGCT cis rs6540559 0.546 rs59435160 chr1:210030730 C/A cg12034118 chr1:209979487 IRF6 0.68 4.83 0.4 3.94e-6 Cleft lip with or without cleft palate; TGCT cis rs877282 0.891 rs12357999 chr10:796468 A/C cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs57590327 0.555 rs13084107 chr3:81833577 T/C cg07356753 chr3:81810745 GBE1 -0.73 -6.73 -0.52 5.57e-10 Extraversion; TGCT cis rs11674184 0.714 rs16857668 chr2:11723110 G/A cg07314298 chr2:11723111 GREB1 -0.43 -7.85 -0.58 1.7e-12 Endometriosis; TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg07636037 chr3:49044803 WDR6 -0.85 -8.91 -0.62 5.44e-15 Menarche (age at onset); TGCT cis rs17253792 0.822 rs77250916 chr14:56042208 A/G cg01858014 chr14:56050164 KTN1 -0.36 -4.57 -0.38 1.15e-5 Putamen volume; TGCT cis rs7917772 0.503 rs56397707 chr10:104302693 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17473412 0.864 rs17408694 chr5:122729230 T/A cg15125798 chr5:122621645 NA -0.55 -4.9 -0.4 2.9e-6 Total body bone mineral density; TGCT cis rs7582180 0.652 rs11694700 chr2:100936637 C/T cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs4780401 0.609 rs9924522 chr16:11816852 C/A cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs259282 0.605 rs17692992 chr19:33099430 T/G cg26639809 chr19:33781782 NA 0.24 4.76 0.39 5.3e-6 Schizophrenia; TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT cis rs9902453 0.868 rs9902340 chr17:28476458 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.73 -6.9 -0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs4972806 0.849 rs2857541 chr2:177029086 C/T cg13092806 chr2:177043255 NA 0.56 4.84 0.4 3.77e-6 IgG glycosylation; TGCT cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg27286337 chr10:134555280 INPP5A 0.37 4.52 0.38 1.4e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9534288 0.797 rs4337200 chr13:46531749 G/A cg15192986 chr13:46630673 CPB2 -0.51 -7.21 -0.54 4.75e-11 Blood protein levels; TGCT cis rs6978712 1.000 rs56040865 chr7:127152442 C/G cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1218582 0.651 rs4845396 chr1:154828409 A/G cg06221963 chr1:154839813 KCNN3 0.53 6.89 0.53 2.54e-10 Prostate cancer; TGCT cis rs12458462 1.000 rs12458462 chr18:77472436 C/A cg11879182 chr18:77439856 CTDP1 0.67 7.52 0.56 9.5e-12 Monocyte count; TGCT cis rs9560113 0.573 rs7988040 chr13:112226534 C/G cg10483660 chr13:112241077 NA 0.31 4.96 0.41 2.27e-6 Menarche (age at onset); TGCT cis rs3749237 0.615 rs6792911 chr3:49429856 C/T cg02487422 chr3:49467188 NICN1 0.61 6.37 0.5 3.31e-9 Resting heart rate; TGCT cis rs801193 1.000 rs7785213 chr7:66138978 A/C cg18876405 chr7:65276391 NA -0.33 -5.05 -0.41 1.55e-6 Aortic root size; TGCT cis rs2243480 0.901 rs13237344 chr7:66022256 T/A cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs6840360 0.533 rs4696295 chr4:152717430 T/C cg22705602 chr4:152727874 NA 0.34 5.91 0.47 3.03e-8 Intelligence (multi-trait analysis); TGCT cis rs4072705 0.967 rs4144630 chr9:127439200 A/G cg13476313 chr9:127244764 NR5A1 0.3 4.88 0.4 3.15e-6 Menarche (age at onset); TGCT cis rs9309473 0.615 rs74523560 chr2:73764185 C/T cg07208825 chr2:73871855 ALMS1P 0.25 4.76 0.39 5.37e-6 Metabolite levels; TGCT cis rs7666738 0.830 rs10034619 chr4:98970067 G/C cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs9972944 0.902 rs9972947 chr17:63771088 G/A cg07283582 chr17:63770753 CCDC46 0.28 5.89 0.47 3.36e-8 Total body bone mineral density; TGCT cis rs2839186 0.656 rs4819226 chr21:47712412 A/G cg12516959 chr21:47718080 NA -0.31 -4.51 -0.38 1.47e-5 Testicular germ cell tumor; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg01802117 chr1:53393560 SCP2 0.39 4.67 0.39 7.55e-6 Monocyte count; TGCT cis rs17122693 0.710 rs8011413 chr14:51160245 A/G cg04730355 chr14:51134070 SAV1 1.15 8.47 0.61 5.79e-14 Cognitive performance; TGCT trans rs9388451 0.839 rs3799711 chr6:126075313 C/T cg05039488 chr6:79577232 IRAK1BP1 0.73 8.44 0.6 6.92e-14 Brugada syndrome; TGCT cis rs694739 1.000 rs499425 chr11:64105929 A/G cg23796481 chr11:64053134 BAD;GPR137 -0.69 -7.23 -0.54 4.44e-11 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs9660992 0.539 rs113699533 chr1:205122895 G/A cg00857998 chr1:205179979 DSTYK 0.48 4.48 0.37 1.68e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs10779751 0.734 rs2261217 chr1:11127764 C/A cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs61931739 0.517 rs7958755 chr12:34294699 T/C cg06521331 chr12:34319734 NA -0.3 -4.55 -0.38 1.28e-5 Morning vs. evening chronotype; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg16325326 chr1:53192061 ZYG11B 0.6 6.77 0.52 4.62e-10 Monocyte count; TGCT cis rs910316 0.737 rs175080 chr14:75513828 G/A cg08847533 chr14:75593920 NEK9 -0.85 -8.45 -0.6 6.56e-14 Height; TGCT cis rs2235642 0.750 rs2974845 chr16:1648162 T/C cg07639376 chr16:1584516 IFT140;TMEM204 -0.28 -4.81 -0.4 4.25e-6 Coronary artery disease; TGCT cis rs9513627 0.573 rs4771336 chr13:100210610 T/G cg25919922 chr13:100150906 NA 0.71 5.66 0.45 1e-7 Obesity-related traits; TGCT cis rs3087591 1.000 rs9902427 chr17:29625430 G/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.29 -0.55 3.12e-11 Hip circumference; TGCT cis rs10504229 0.683 rs6980540 chr8:58127022 A/G cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs151997 1.000 rs251043 chr5:50215997 A/G cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.68 -0.66 7.64e-17 Platelet count; TGCT cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.1 -0.42 1.22e-6 Electroencephalogram traits; TGCT cis rs5750830 0.645 rs756640 chr22:39779300 G/A cg11247378 chr22:39784982 NA -0.74 -10.6 -0.69 4.31e-19 Intelligence (multi-trait analysis); TGCT cis rs6893300 0.524 rs12522926 chr5:179214818 G/A cg14593053 chr5:179126677 CANX 0.49 5.66 0.45 1.01e-7 Resting heart rate; TGCT cis rs904251 0.523 rs9349039 chr6:37480392 A/G cg08126542 chr6:37504118 NA -0.46 -6.46 -0.5 2.11e-9 Cognitive performance; TGCT cis rs709400 0.663 rs8015918 chr14:103942991 A/G cg26031613 chr14:104095156 KLC1 0.85 9.72 0.66 5.87e-17 Body mass index; TGCT cis rs1005224 0.889 rs2059382 chr14:76158916 T/C cg25116370 chr14:76127843 TTLL5;C14orf1 -0.54 -4.67 -0.39 7.82e-6 Large artery stroke; TGCT trans rs10802346 0.514 rs5024440 chr1:246372608 G/C cg13514129 chr1:39547527 MACF1 0.83 7.31 0.55 2.94e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg13770153 chr20:60521292 NA -0.61 -8.97 -0.63 3.88e-15 Obesity-related traits; TGCT cis rs72781680 1.000 rs17712391 chr2:24245659 C/T cg08917208 chr2:24149416 ATAD2B 0.85 5.13 0.42 1.08e-6 Lymphocyte counts; TGCT cis rs9486719 1.000 rs35487471 chr6:96879715 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7246657 0.722 rs2927746 chr19:38156570 G/A cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT cis rs9916302 0.904 rs10491128 chr17:37551988 G/A cg15445000 chr17:37608096 MED1 -0.35 -5.04 -0.41 1.61e-6 Glomerular filtration rate (creatinine); TGCT cis rs7786808 0.712 rs2335170 chr7:158207101 G/A cg01191920 chr7:158217561 PTPRN2 -0.44 -6.74 -0.52 5.44e-10 Obesity-related traits; TGCT cis rs453301 0.686 rs6601281 chr8:8911004 A/G cg06636001 chr8:8085503 FLJ10661 -0.72 -6.0 -0.47 2.04e-8 Joint mobility (Beighton score); TGCT cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg12667521 chr19:29218732 NA 0.54 5.72 0.46 7.65e-8 Methadone dose in opioid dependence; TGCT cis rs763121 0.853 rs3747174 chr22:39069181 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs7809950 0.954 rs2894466 chr7:107242909 G/A cg23024343 chr7:107201750 COG5 0.33 5.29 0.43 5.36e-7 Coronary artery disease; TGCT cis rs6089584 0.853 rs1746280 chr20:60577821 C/G cg06108461 chr20:60628389 TAF4 -0.61 -8.86 -0.62 6.96e-15 Body mass index; TGCT cis rs4319547 0.728 rs61954974 chr12:123074169 T/C cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.38 -0.44 3.5e-7 Body mass index; TGCT cis rs6598955 0.671 rs11579354 chr1:26604071 T/G cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs1552244 0.572 rs73117481 chr3:10160132 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs853679 0.517 rs9393884 chr6:28046789 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs67311347 0.869 rs6790495 chr3:40366770 C/T cg13683864 chr3:40499215 RPL14 -1.05 -10.95 -0.7 6.12e-20 Renal cell carcinoma; TGCT cis rs9324022 0.626 rs10873520 chr14:101175967 G/A cg18089426 chr14:101175970 NA 0.63 5.96 0.47 2.38e-8 Plateletcrit; TGCT cis rs9611565 1.000 rs5751086 chr22:41768862 C/T cg13695892 chr22:41940480 POLR3H -0.73 -7.41 -0.55 1.69e-11 Vitiligo; TGCT cis rs9926296 0.632 rs7206546 chr16:89799079 C/T cg08627397 chr16:89984028 MC1R 0.31 4.99 0.41 2.02e-6 Vitiligo; TGCT cis rs6754311 0.731 rs3754686 chr2:136603276 T/C cg07169764 chr2:136633963 MCM6 -0.66 -6.05 -0.48 1.6e-8 Mosquito bite size; TGCT cis rs8072100 0.840 rs12452796 chr17:45479733 G/T cg08085267 chr17:45401833 C17orf57 0.5 5.69 0.46 8.53e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs483180 0.512 rs606312 chr1:120222582 G/A cg19096424 chr1:120255104 PHGDH 0.55 5.1 0.42 1.23e-6 Macular telangiectasia type 2; TGCT cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg06481639 chr22:41940642 POLR3H 0.69 6.02 0.48 1.83e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs36051895 0.632 rs7850484 chr9:5147817 C/T cg02405213 chr9:5042618 JAK2 -0.76 -9.88 -0.66 2.47e-17 Pediatric autoimmune diseases; TGCT cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs6460942 1.000 rs75333414 chr7:12303829 T/A cg06484146 chr7:12443880 VWDE -0.53 -4.73 -0.39 6.07e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs28594127 chr4:99001121 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6088580 0.609 rs6059844 chr20:33036482 A/G cg06115741 chr20:33292138 TP53INP2 0.52 4.71 0.39 6.55e-6 Glomerular filtration rate (creatinine); TGCT cis rs9467711 1.000 rs34569761 chr6:26334306 A/G cg16898833 chr6:26189333 HIST1H4D 1.04 5.41 0.44 3.12e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9527 0.615 rs36045108 chr10:104697929 G/A cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs2180341 0.618 rs11154396 chr6:127638911 C/T cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs4699052 0.963 rs7657390 chr4:104213114 T/A cg16532752 chr4:104119610 CENPE -0.56 -5.05 -0.41 1.57e-6 Testicular germ cell tumor; TGCT cis rs954108 0.772 rs9508154 chr13:29370726 A/G cg11788234 chr13:29393811 NA -0.41 -5.17 -0.42 9.07e-7 Obesity-related traits; TGCT cis rs1843834 0.505 rs3820763 chr2:225347270 A/G cg12698349 chr2:225449008 CUL3 -0.76 -6.38 -0.5 3.26e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs936229 0.511 rs12591513 chr15:75102714 G/A cg10253484 chr15:75165896 SCAMP2 -0.68 -6.04 -0.48 1.63e-8 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs9611565 0.694 rs4822032 chr22:41925535 T/C cg17554472 chr22:41940697 POLR3H -0.45 -5.1 -0.42 1.22e-6 Vitiligo; TGCT cis rs2997447 0.761 rs17257107 chr1:26448447 A/G cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT trans rs28735056 0.592 rs12455965 chr18:77688830 G/C cg05926928 chr17:57297772 GDPD1 -0.68 -6.75 -0.52 5.1e-10 Schizophrenia; TGCT cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg03161606 chr19:29218774 NA 0.6 5.84 0.46 4.28e-8 Methadone dose in opioid dependence; TGCT cis rs904251 0.600 rs1874736 chr6:37447994 C/G cg25019722 chr6:37503610 NA -0.48 -6.92 -0.53 2.1e-10 Cognitive performance; TGCT cis rs3857536 0.544 rs208453 chr6:66906841 A/T cg07460842 chr6:66804631 NA -0.68 -6.73 -0.52 5.5e-10 Blood trace element (Cu levels); TGCT cis rs7647973 0.593 rs7620848 chr3:49828021 G/C cg05785598 chr3:49045655 WDR6 -0.42 -5.24 -0.43 6.67e-7 Menarche (age at onset); TGCT cis rs1568889 1.000 rs16917735 chr11:28119980 A/T cg06544937 chr11:28130018 METT5D1;KIF18A -0.84 -8.78 -0.62 1.09e-14 Bipolar disorder; TGCT cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs412000 0.554 rs2680700 chr17:56440542 G/T cg25039879 chr17:56429692 SUPT4H1 0.62 5.94 0.47 2.63e-8 Primary tooth development (time to first tooth eruption); TGCT cis rs4689388 0.926 rs10010131 chr4:6292915 A/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs853679 0.517 rs9295758 chr6:28120663 C/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs6912958 0.684 rs4707382 chr6:88320641 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.57 -0.38 1.16e-5 Monocyte percentage of white cells; TGCT cis rs9308731 0.644 rs1821968 chr2:111880623 C/T cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.1e-9 Chronic lymphocytic leukemia; TGCT cis rs10089 1.000 rs10478796 chr5:127436187 A/G cg19767477 chr5:127420684 SLC12A2 -0.43 -4.52 -0.38 1.43e-5 Ileal carcinoids; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg17178900 chr1:205818956 PM20D1 0.58 6.97 0.53 1.66e-10 Menarche (age at onset); TGCT cis rs13082711 0.522 rs674303 chr3:27332177 T/C cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs6840360 0.593 rs6855883 chr4:152688997 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.16 -0.42 9.49e-7 Intelligence (multi-trait analysis); TGCT cis rs853679 0.546 rs200948 chr6:27835272 T/C cg10876282 chr6:28092338 ZSCAN16 0.75 4.45 0.37 1.88e-5 Depression; TGCT cis rs11578119 0.864 rs6667728 chr1:170493407 A/G cg09767346 chr1:170501363 GORAB 0.66 5.2 0.42 7.84e-7 Male-pattern baldness; TGCT cis rs4631830 0.900 rs7075009 chr10:51544143 T/G cg10326726 chr10:51549505 MSMB -0.26 -5.28 -0.43 5.5e-7 Prostate-specific antigen levels; TGCT cis rs7769051 0.522 rs62424539 chr6:133173272 C/T cg22852734 chr6:133119734 C6orf192 1.1 5.45 0.44 2.61e-7 Type 2 diabetes nephropathy; TGCT trans rs12339966 0.653 rs7037356 chr9:11300688 G/A cg07173112 chr1:1114698 TTLL10 -0.34 -6.8 -0.52 4.02e-10 Systolic blood pressure; TGCT cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg16049864 chr8:95962084 TP53INP1 -0.7 -9.94 -0.67 1.76e-17 Type 2 diabetes; TGCT cis rs2576037 0.583 rs9954336 chr18:44465945 A/G cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs11719291 0.833 rs11713694 chr3:48833615 G/T cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 Cognitive function; TGCT cis rs6570726 1.000 rs450076 chr6:145847655 G/T cg23711669 chr6:146136114 FBXO30 0.68 6.26 0.49 5.81e-9 Lobe attachment (rater-scored or self-reported); TGCT trans rs7726839 0.507 rs72703100 chr5:614291 C/T cg11887960 chr12:57824829 NA 1.19 9.29 0.64 6.45e-16 Obesity-related traits; TGCT cis rs597539 0.652 rs604524 chr11:68629929 G/A cg21963583 chr11:68658836 MRPL21 0.38 6.43 0.5 2.51e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs453301 0.522 rs2929309 chr8:9083771 C/A cg15556689 chr8:8085844 FLJ10661 -0.61 -5.63 -0.45 1.14e-7 Joint mobility (Beighton score); TGCT cis rs9341808 0.739 rs4706831 chr6:81007699 T/C cg08355045 chr6:80787529 NA 0.28 4.75 0.39 5.54e-6 Sitting height ratio; TGCT cis rs7000551 0.715 rs1879792 chr8:22314029 C/A cg12081754 chr8:22256438 SLC39A14 0.31 5.17 0.42 9.19e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg01802117 chr1:53393560 SCP2 -0.39 -4.61 -0.38 1e-5 Monocyte count; TGCT cis rs9733 0.650 rs1971378 chr1:150597261 C/T cg13175981 chr1:150552382 MCL1 0.47 5.29 0.43 5.27e-7 Tonsillectomy; TGCT cis rs3806843 1.000 rs13184940 chr5:140172918 T/C cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4808199 0.894 rs10418051 chr19:19397789 C/T cg03709012 chr19:19516395 GATAD2A 0.81 6.55 0.51 1.41e-9 Nonalcoholic fatty liver disease; TGCT cis rs4478858 0.735 rs11590120 chr1:31792324 A/G cg00250761 chr1:31883323 NA -0.27 -4.78 -0.39 4.86e-6 Alcohol dependence; TGCT cis rs250677 0.687 rs250673 chr5:148445798 C/T cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs10883723 0.810 rs1056857 chr10:104240003 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs807669 0.807 rs698422 chr22:19205826 A/T cg02655711 chr22:19163373 SLC25A1 0.33 7.25 0.55 3.9e-11 Metabolite levels; TGCT cis rs28595532 0.920 rs116717907 chr4:119762568 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs8072100 0.967 rs12452315 chr17:45479446 G/T cg08085267 chr17:45401833 C17orf57 0.48 5.41 0.44 3.12e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg10207240 chr12:122356781 WDR66 0.33 4.54 0.38 1.31e-5 Mean corpuscular volume; TGCT cis rs10504229 0.683 rs55868006 chr8:58135703 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs6582630 0.537 rs7310749 chr12:38400472 C/T cg13010199 chr12:38710504 ALG10B 0.59 4.68 0.39 7.35e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2836974 0.583 rs9981884 chr21:40585633 G/A cg11644478 chr21:40555479 PSMG1 0.71 7.25 0.55 3.94e-11 Cognitive function; TGCT cis rs7666738 0.512 rs165251 chr4:98758490 C/G cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 1.000 rs4815404 chr20:25301845 T/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1555895 0.633 rs7913077 chr10:845969 T/C cg02193355 chr10:851439 NA 0.22 4.71 0.39 6.6e-6 Survival in rectal cancer; TGCT cis rs56309584 0.715 rs74506939 chr17:8139463 G/A cg08322244 chr17:8066669 VAMP2 -0.57 -5.26 -0.43 6.01e-7 Initial pursuit acceleration; TGCT cis rs9649213 0.586 rs55648546 chr7:97960800 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.48 -0.61 5.64e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs838147 0.507 rs1704773 chr19:49209566 A/G cg04599840 chr19:48886497 KDELR1 0.21 4.44 0.37 1.98e-5 Dietary macronutrient intake; TGCT cis rs2072499 0.932 rs3001790 chr1:156165290 T/G cg25208724 chr1:156163844 SLC25A44 1.14 16.93 0.84 4.87e-34 Testicular germ cell tumor; TGCT cis rs6429082 0.818 rs291341 chr1:235663174 G/T cg26050004 chr1:235667680 B3GALNT2 0.59 5.16 0.42 9.52e-7 Adiposity; TGCT cis rs11098499 0.754 rs1511025 chr4:120240238 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs12935418 0.583 rs80181133 chr16:80967950 G/T cg07676361 chr16:80966860 NA -0.34 -4.54 -0.38 1.31e-5 Mean corpuscular volume; TGCT cis rs79349575 0.715 rs11657238 chr17:46985634 A/G cg07967210 chr17:47022446 SNF8 0.41 5.44 0.44 2.69e-7 Type 2 diabetes; TGCT cis rs10992471 0.756 rs2516568 chr9:95187380 A/T cg14631576 chr9:95140430 CENPP -0.3 -4.97 -0.41 2.21e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6121246 0.909 rs4518038 chr20:30419051 A/G cg13852791 chr20:30311386 BCL2L1 0.67 4.63 0.38 9.04e-6 Mean corpuscular hemoglobin; TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg22166914 chr1:53195759 ZYG11B 0.34 5.71 0.46 7.92e-8 Monocyte count; TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg13189271 chr6:15365693 JARID2 0.99 5.2 0.42 7.9e-7 Gambling; TGCT cis rs2334880 0.836 rs9934715 chr16:71757387 C/G cg06353428 chr16:71660113 MARVELD3 1.49 12.95 0.76 8.56e-25 Malaria; TGCT cis rs7586879 0.616 rs6545814 chr2:25131316 A/G cg15423357 chr2:25149977 NA 0.48 4.62 0.38 9.44e-6 Body mass index; TGCT cis rs6460942 0.749 rs74834695 chr7:12464779 G/A cg06484146 chr7:12443880 VWDE -0.57 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT cis rs9443645 0.869 rs1567168 chr6:79536455 G/T cg05283184 chr6:79620031 NA -0.21 -4.64 -0.38 8.56e-6 Intelligence (multi-trait analysis); TGCT cis rs55882075 0.765 rs34329357 chr5:179130408 G/C cg14593053 chr5:179126677 CANX 0.52 5.69 0.46 8.52e-8 Monocyte percentage of white cells; TGCT cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg17554472 chr22:41940697 POLR3H 0.48 5.06 0.41 1.5e-6 Vitiligo; TGCT cis rs9814567 0.752 rs1880378 chr3:134330709 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3782455 0.793 rs2290800 chr12:114404383 T/G cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7772486 0.790 rs2265469 chr6:146219049 T/C cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.89e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.753 rs28463863 chr4:98844444 T/C cg05340658 chr4:99064831 C4orf37 0.52 6.05 0.48 1.6e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 1.000 rs4917901 chr10:102201773 A/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs17376456 0.825 rs12153021 chr5:93073913 A/G cg09848695 chr5:92956644 FAM172A;MIR2277 0.63 4.43 0.37 2.01e-5 Diabetic retinopathy; TGCT cis rs8111998 0.702 rs16999400 chr19:22768608 A/G cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg18305652 chr10:134549665 INPP5A 0.35 5.64 0.45 1.1e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7772486 0.875 rs1125461 chr6:146417653 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.72 0.39 6.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6424115 0.830 rs2502992 chr1:24201919 T/C cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs986417 1.000 rs1254302 chr14:60885343 A/C cg27398547 chr14:60952738 C14orf39 -1.42 -8.68 -0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs7246657 0.943 rs1559229 chr19:37876197 T/C cg03233940 chr19:37894644 NA -0.35 -4.54 -0.38 1.3e-5 Coronary artery calcification; TGCT cis rs2857078 1.000 rs2857078 chr17:42330171 A/C cg13607699 chr17:42295918 UBTF -0.89 -8.56 -0.61 3.65e-14 Red cell distribution width;Reticulocyte count; TGCT cis rs11587682 0.785 rs72694993 chr1:150242604 A/C cg18798344 chr1:149336151 NA 0.56 4.48 0.37 1.7e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10927875 0.518 rs945416 chr1:16344402 G/A cg22431228 chr1:16359049 CLCNKA -0.29 -5.94 -0.47 2.68e-8 Dilated cardiomyopathy; TGCT cis rs9443189 0.570 rs9341532 chr6:76403674 A/G cg01950844 chr6:76311363 SENP6 1.0 6.24 0.49 6.35e-9 Prostate cancer; TGCT cis rs11718455 0.883 rs2372579 chr3:44034003 A/T cg08738300 chr3:44038990 NA 0.86 6.57 0.51 1.23e-9 Coronary artery disease; TGCT cis rs651907 0.588 rs1707613 chr3:101637189 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.5 4.79 0.4 4.65e-6 Colorectal cancer; TGCT cis rs79387448 0.745 rs7587856 chr2:103144305 C/A cg09003973 chr2:102972529 NA 0.98 6.36 0.5 3.57e-9 Gut microbiota (bacterial taxa); TGCT cis rs1865760 0.865 rs1115920 chr6:25954027 A/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT trans rs1814175 0.592 rs1794161 chr11:49898825 A/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.58 -0.69 4.9e-19 Height; TGCT cis rs2549003 1.000 rs6894655 chr5:131818649 T/C cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg05368731 chr17:41323189 NBR1 1.05 11.03 0.7 3.86e-20 Menopause (age at onset); TGCT cis rs10489202 0.683 rs202260 chr1:167956167 G/T cg24449463 chr1:168025552 DCAF6 -0.59 -7.11 -0.54 8.22e-11 Schizophrenia; TGCT cis rs2153535 0.580 rs9505454 chr6:8478532 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs17253792 0.822 rs28831725 chr14:56087569 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT trans rs916888 0.610 rs199442 chr17:44820122 G/A cg10053473 chr17:62856997 LRRC37A3 -0.41 -6.76 -0.52 4.9e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2112347 0.502 rs34339 chr5:74931333 G/T cg19683494 chr5:74908142 NA -0.65 -6.25 -0.49 6.16e-9 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; TGCT cis rs9831754 0.906 rs9840031 chr3:78396140 C/T cg06138941 chr3:78371609 NA 0.49 5.4 0.44 3.25e-7 Calcium levels; TGCT cis rs35306767 0.953 rs10904583 chr10:983498 T/C cg18964960 chr10:1102726 WDR37 0.56 4.58 0.38 1.12e-5 Eosinophil percentage of granulocytes; TGCT cis rs2836633 0.894 rs55955614 chr21:40037330 T/G cg12884169 chr21:40033163 ERG 0.45 4.98 0.41 2.13e-6 Coronary artery disease; TGCT cis rs3796352 1.000 rs35174175 chr3:53041509 T/C cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs459571 0.920 rs433402 chr9:136898627 A/G cg13789015 chr9:136890014 NCRNA00094 0.41 7.73 0.57 3.16e-12 Platelet distribution width; TGCT cis rs3540 0.597 rs4620932 chr15:91036569 G/A cg22089800 chr15:90895588 ZNF774 0.76 7.77 0.57 2.62e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs11098499 0.863 rs3775845 chr4:120432447 T/C cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs9611565 0.506 rs4822020 chr22:41700203 C/T cg06634786 chr22:41940651 POLR3H -0.63 -5.66 -0.45 1.01e-7 Vitiligo; TGCT cis rs7213347 0.707 rs2038677 chr17:2178092 C/G cg13315690 chr17:1944831 OVCA2;DPH1 -0.37 -4.7 -0.39 6.76e-6 Total body bone mineral density; TGCT cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.99 -0.41 2e-6 Bipolar disorder; TGCT cis rs10871290 0.551 rs3863435 chr16:74465396 C/G cg01733217 chr16:74700730 RFWD3 -0.66 -6.71 -0.52 6.2e-10 Breast cancer; TGCT cis rs11671005 0.695 rs8106061 chr19:58917990 G/A cg13877915 chr19:58951672 ZNF132 0.64 5.05 0.41 1.51e-6 Mean platelet volume; TGCT cis rs2562456 0.917 rs2650793 chr19:21676115 C/G cg25650185 chr19:21324782 ZNF431 0.57 5.03 0.41 1.67e-6 Pain; TGCT cis rs36051895 0.623 rs6476952 chr9:5236924 T/C cg02405213 chr9:5042618 JAK2 -0.69 -8.52 -0.61 4.64e-14 Pediatric autoimmune diseases; TGCT cis rs3796352 1.000 rs11712653 chr3:53070875 A/C cg24616795 chr3:53032891 SFMBT1 -0.38 -4.73 -0.39 5.99e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1577917 0.958 rs66807489 chr6:86440702 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.4 -0.44 3.28e-7 Response to antipsychotic treatment; TGCT cis rs4566357 0.595 rs10201538 chr2:227914449 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT trans rs6089829 0.962 rs6122352 chr20:61668284 T/C cg17470723 chr8:74884337 TCEB1 0.72 6.87 0.53 2.78e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7412746 0.646 rs10399947 chr1:150861960 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 4.64 0.38 8.63e-6 Melanoma; TGCT cis rs7607369 0.626 rs4672892 chr2:219278630 A/G cg02176678 chr2:219576539 TTLL4 -0.49 -6.24 -0.49 6.26e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs7833790 1.000 rs1463259 chr8:82737745 A/G cg17211192 chr8:82754475 SNX16 -1.08 -8.89 -0.62 6.01e-15 Diastolic blood pressure; TGCT cis rs8017423 0.935 rs11628952 chr14:90734953 T/C cg04374321 chr14:90722782 PSMC1 -0.75 -7.32 -0.55 2.75e-11 Mortality in heart failure; TGCT cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs9388451 0.626 rs1739384 chr6:126099246 C/A cg05901451 chr6:126070800 HEY2 -0.92 -11.38 -0.71 5.49e-21 Brugada syndrome; TGCT cis rs6840360 0.615 rs12641441 chr4:152607623 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.13 -0.48 1.1e-8 Intelligence (multi-trait analysis); TGCT cis rs881375 0.678 rs4836834 chr9:123665901 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.92e-7 Rheumatoid arthritis; TGCT cis rs896854 0.818 rs896855 chr8:95959808 A/G cg23172400 chr8:95962367 TP53INP1 -0.39 -6.48 -0.5 1.99e-9 Type 2 diabetes; TGCT cis rs17376456 0.569 rs11135394 chr5:93187135 C/T cg25358565 chr5:93447407 FAM172A -0.6 -5.47 -0.44 2.38e-7 Diabetic retinopathy; TGCT cis rs79349575 0.655 rs62078384 chr17:47044463 C/T cg26022315 chr17:47021804 SNF8 0.47 4.56 0.38 1.2e-5 Type 2 diabetes; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg25703541 chr22:24373054 LOC391322 0.86 8.27 0.6 1.72e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9807989 0.839 rs3771166 chr2:102986222 G/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs4975616 0.804 rs456366 chr5:1337070 T/C cg07493874 chr5:1342172 CLPTM1L -0.28 -6.85 -0.52 3.06e-10 Lung cancer; TGCT cis rs35306767 0.953 rs1539174 chr10:974870 C/G cg20503657 chr10:835505 NA 0.56 7.77 0.57 2.63e-12 Eosinophil percentage of granulocytes; TGCT trans rs57221529 0.655 rs11948381 chr5:568413 A/T cg25482853 chr8:67687455 SGK3 1.11 8.76 0.62 1.19e-14 Lung disease severity in cystic fibrosis; TGCT cis rs11098499 0.874 rs17839089 chr4:120111069 A/G cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs12477438 0.520 rs2516829 chr2:99773201 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.1 15.5 0.81 8.29e-31 Chronic sinus infection; TGCT cis rs3540 0.512 rs11633872 chr15:91080512 G/A cg22089800 chr15:90895588 ZNF774 -0.74 -7.57 -0.56 7.35e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2228479 0.850 rs3785279 chr16:89824562 G/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs600550 0.927 rs603568 chr11:59981619 T/C cg18570331 chr11:60101691 MS4A6E 0.52 4.84 0.4 3.79e-6 Lipoprotein-associated phospholipase A2 activity and mass; TGCT cis rs13256369 1.000 rs10110591 chr8:8576608 G/T cg06671706 chr8:8559999 CLDN23 -0.35 -4.62 -0.38 9.33e-6 Obesity-related traits; TGCT cis rs10791323 0.536 rs4937842 chr11:133734542 C/G cg15485101 chr11:133734466 NA -0.42 -5.94 -0.47 2.71e-8 Childhood ear infection; TGCT cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg09323728 chr8:95962352 TP53INP1 0.45 5.26 0.43 6.17e-7 Type 2 diabetes; TGCT cis rs7000551 0.751 rs1116085 chr8:22394920 A/G cg12081754 chr8:22256438 SLC39A14 0.29 4.61 0.38 1e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4924935 1.000 rs2158100 chr17:18811479 A/G cg26378065 chr17:18585709 ZNF286B -0.56 -4.71 -0.39 6.6e-6 Pancreatic cancer; TGCT cis rs9467773 1.000 rs6930120 chr6:26555484 A/G cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT trans rs6089829 0.962 rs6089825 chr20:61668447 C/T cg13615516 chr5:77269221 NA 0.72 9.11 0.63 1.74e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs1008375 0.966 rs1476836 chr4:17585014 G/C cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7584330 0.910 rs12465081 chr2:238401784 A/G cg16989719 chr2:238392110 NA -0.27 -4.89 -0.4 3.06e-6 Prostate cancer; TGCT cis rs2735413 0.564 rs11863846 chr16:78119557 C/G cg09132178 chr16:78079569 NA 0.35 4.51 0.38 1.47e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs9902453 0.967 rs61240589 chr17:28449035 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg01802117 chr1:53393560 SCP2 -0.48 -5.77 -0.46 6.09e-8 Monocyte count; TGCT cis rs2932538 0.922 rs6658555 chr1:113098534 C/T cg22162597 chr1:113214053 CAPZA1 0.29 6.34 0.49 3.95e-9 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs67460515 0.892 rs4856769 chr3:161004549 C/A cg03342759 chr3:160939853 NMD3 -0.55 -5.82 -0.46 4.68e-8 Parkinson's disease; TGCT cis rs9814567 0.928 rs6768323 chr3:134268737 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg03517284 chr6:25882590 NA -0.48 -4.78 -0.39 4.78e-6 Height; TGCT cis rs813218 0.584 rs1718240 chr3:99536937 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.48 5.36 0.43 3.97e-7 Orofacial clefts; TGCT cis rs10791097 0.694 rs4264159 chr11:130755784 G/T cg14779329 chr11:130786720 SNX19 0.29 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs2710642 0.962 rs4671051 chr2:63032696 A/T cg17519650 chr2:63277830 OTX1 -0.64 -5.83 -0.46 4.47e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs77551289 0.512 rs4987853 chr18:60793655 A/G cg14455307 chr18:60987429 BCL2 -0.57 -4.48 -0.37 1.69e-5 Chronic lymphocytic leukemia; TGCT cis rs1894292 0.527 rs2178290 chr4:74376846 C/T cg05868023 chr4:75230803 EREG 0.56 5.07 0.41 1.42e-6 Prostate cancer; TGCT cis rs74417235 0.684 rs7723312 chr5:154053249 A/G cg08754654 chr5:154026448 NA -0.58 -5.53 -0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs4927850 0.881 rs7630489 chr3:195753401 T/C cg12923728 chr3:195709715 SDHAP1 -0.36 -7.57 -0.56 7.39e-12 Pancreatic cancer; TGCT cis rs4727027 0.631 rs62507511 chr7:148796080 C/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.6 0.38 1.05e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3806843 0.548 rs246052 chr5:140326413 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs597539 0.652 rs514833 chr11:68657734 C/T cg06112835 chr11:68658793 MRPL21 0.47 8.03 0.59 6.25e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1555895 0.656 rs1536338 chr10:838378 C/T cg02193355 chr10:851439 NA -0.23 -5.04 -0.41 1.6e-6 Survival in rectal cancer; TGCT cis rs2468186 0.583 rs2450069 chr8:120095828 A/G cg02248809 chr8:120845432 TAF2 -0.45 -4.83 -0.4 3.99e-6 Osteoprotegerin levels; TGCT cis rs295140 0.507 rs13019821 chr2:201106815 C/G cg23649088 chr2:200775458 C2orf69 -0.34 -5.87 -0.47 3.76e-8 QT interval; TGCT cis rs10992471 0.603 rs7873397 chr9:95205928 G/C cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.74 -0.46 6.79e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4665809 0.549 rs3828255 chr2:26413252 G/A cg04944784 chr2:26401820 FAM59B 0.79 5.45 0.44 2.58e-7 Gut microbiome composition (summer); TGCT cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg03264133 chr6:25882463 NA -0.64 -5.74 -0.46 6.9e-8 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg15242686 chr22:24348715 GSTTP1 0.5 7.46 0.56 1.34e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7095607 0.967 rs12785105 chr10:69964794 C/T cg18986048 chr10:69913749 MYPN 0.42 4.49 0.37 1.62e-5 Lung function (FVC); TGCT cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs270601 0.909 rs2569265 chr5:131704519 T/C cg24060327 chr5:131705240 SLC22A5 0.78 8.62 0.61 2.62e-14 Acylcarnitine levels; TGCT cis rs7959452 0.590 rs10878974 chr12:69781528 C/G cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs10892173 0.566 rs12364667 chr11:117675286 A/C cg07621104 chr11:117668040 DSCAML1 0.74 8.11 0.59 4.06e-13 Myopia; TGCT cis rs9486719 0.843 rs2499796 chr6:96848364 A/G cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs7226408 0.857 rs72887084 chr18:34503982 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs910187 0.605 rs6066224 chr20:45806632 T/A cg27589058 chr20:45804311 EYA2 -0.38 -8.27 -0.6 1.74e-13 Migraine; TGCT cis rs2404602 0.692 rs2304920 chr15:76993867 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs9814567 1.000 rs6772896 chr3:134203347 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.97 -9.24 -0.64 8.89e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3820068 0.581 rs16851876 chr1:15950628 A/T cg05660106 chr1:15850417 CASP9 -0.79 -7.66 -0.57 4.64e-12 Systolic blood pressure; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg07205460 chr22:24236375 MIF 0.57 4.46 0.37 1.78e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs12048904 0.505 rs10493936 chr1:101213335 A/T cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.64 -5.46 -0.44 2.54e-7 Multiple sclerosis; TGCT trans rs57221529 0.713 rs72703072 chr5:590626 A/G cg25482853 chr8:67687455 SGK3 1.22 10.56 0.69 5.48e-19 Lung disease severity in cystic fibrosis; TGCT cis rs8078723 0.714 rs2241245 chr17:38151014 C/T cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg03806693 chr22:41940476 POLR3H 1.02 11.39 0.72 5.21e-21 Vitiligo; TGCT cis rs7412746 0.611 rs10888391 chr1:150729983 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.57 0.38 1.15e-5 Melanoma; TGCT cis rs4819052 1.000 rs28628220 chr21:46663741 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.87 7.26 0.55 3.73e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13401104 0.587 rs6731967 chr2:237145606 G/C cg19324714 chr2:237145437 ASB18 0.55 6.17 0.48 8.81e-9 Educational attainment; TGCT cis rs9787249 0.957 rs7518431 chr1:40214944 C/T cg19912559 chr1:40204330 PPIE -0.45 -5.33 -0.43 4.49e-7 Blood protein levels; TGCT cis rs1555895 0.576 rs4881537 chr10:848059 A/T cg02193355 chr10:851439 NA 0.23 5.23 0.43 6.88e-7 Survival in rectal cancer; TGCT cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg20637647 chr7:64974828 NA 0.84 4.85 0.4 3.63e-6 Diabetic kidney disease; TGCT cis rs74233809 1.000 rs10883815 chr10:104739179 T/C cg05855489 chr10:104503620 C10orf26 0.74 4.44 0.37 1.96e-5 Birth weight; TGCT cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg07507251 chr3:52567010 NT5DC2 0.43 5.86 0.47 3.94e-8 Bipolar disorder; TGCT cis rs473651 0.777 rs550890 chr2:239332555 G/A cg18131467 chr2:239335373 ASB1 0.99 10.74 0.69 1.96e-19 Multiple system atrophy; TGCT cis rs7192750 0.563 rs7184486 chr16:71886530 T/A cg06353428 chr16:71660113 MARVELD3 0.8 7.29 0.55 3.15e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs78487399 0.710 rs76857293 chr2:43591676 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4478858 0.624 rs10914333 chr1:31701491 A/G cg00250761 chr1:31883323 NA -0.28 -4.67 -0.39 7.77e-6 Alcohol dependence; TGCT cis rs2836950 0.501 rs4818019 chr21:40694456 T/A cg06238570 chr21:40685208 BRWD1 -0.63 -6.47 -0.5 2.02e-9 Menarche (age at onset); TGCT cis rs704 0.605 rs2227736 chr17:26693231 G/C cg10494684 chr17:26645200 TMEM97 -0.46 -4.95 -0.41 2.33e-6 Osteoprotegerin levels; TGCT cis rs7666738 0.830 rs4334758 chr4:98971875 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs2710642 0.566 rs2710651 chr2:63166379 G/A cg17519650 chr2:63277830 OTX1 0.69 6.61 0.51 1.04e-9 LDL cholesterol levels;LDL cholesterol; TGCT cis rs2933343 0.533 rs13086121 chr3:128704290 A/T cg11901034 chr3:128598214 ACAD9 -0.56 -5.26 -0.43 6.23e-7 IgG glycosylation; TGCT cis rs1799949 1.000 rs2298862 chr17:41176688 T/C cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs6570726 0.791 rs6918814 chr6:145906028 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.32 0.55 2.77e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs4654899 0.680 rs6704421 chr1:21220674 A/C cg01072550 chr1:21505969 NA 0.55 8.94 0.63 4.56e-15 Superior frontal gyrus grey matter volume; TGCT cis rs3741151 1.000 rs75114310 chr11:73042047 C/T cg17517138 chr11:73019481 ARHGEF17 1.22 6.25 0.49 5.95e-9 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs10411936 1.000 rs1870071 chr19:16505106 A/G cg14704714 chr19:15740395 CYP4F8 -0.25 -4.44 -0.37 2e-5 White blood cell count;Multiple sclerosis; TGCT cis rs1505368 0.837 rs10167244 chr2:213281310 A/G cg16329650 chr2:213403929 ERBB4 0.61 6.14 0.48 1.04e-8 Symmetrical dimethylarginine levels; TGCT cis rs853679 0.574 rs1233705 chr6:28166447 C/G cg12963246 chr6:28129442 ZNF389 0.48 4.74 0.39 5.69e-6 Depression; TGCT cis rs9911578 0.765 rs66954617 chr17:56999427 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.933 rs6138571 chr20:25435388 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2472297 1.000 rs2472297 chr15:75027880 A/G cg10253484 chr15:75165896 SCAMP2 0.67 4.76 0.39 5.25e-6 Caffeine metabolism (plasma 1,3,7-trimethylxanthine (caffeine) level);Coffee consumption (cups per day);Coffee consumption;Caffeine metabolism (plasma 1,3-dimethylxanthine (theophylline) level);Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); TGCT cis rs7246657 0.943 rs3745765 chr19:37854235 G/T cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.3e-7 Coronary artery calcification; TGCT cis rs9611565 0.729 rs203319 chr22:41914593 C/T cg17554472 chr22:41940697 POLR3H -0.47 -5.27 -0.43 5.92e-7 Vitiligo; TGCT cis rs9436747 0.667 rs4655518 chr1:66039858 G/T cg14976592 chr1:65886160 LEPROT;LEPR -0.58 -5.47 -0.44 2.33e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs477895 1.000 rs34292685 chr11:64049021 C/T cg23719950 chr11:63933701 MACROD1 -0.57 -4.49 -0.37 1.63e-5 Mean platelet volume; TGCT cis rs11122272 0.735 rs2572263 chr1:231509408 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg10047753 chr17:41438598 NA 0.96 9.54 0.65 1.61e-16 Menopause (age at onset); TGCT cis rs66573146 0.539 rs56659624 chr4:7069377 G/C cg26116260 chr4:7069785 GRPEL1 -0.92 -4.45 -0.37 1.87e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs6938 0.618 rs12911254 chr15:75166335 G/A cg10253484 chr15:75165896 SCAMP2 -0.6 -5.5 -0.44 2.06e-7 Breast cancer; TGCT cis rs2637266 1.000 rs12414151 chr10:78359041 T/G cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs904251 0.523 rs2797799 chr6:37483620 T/G cg25019722 chr6:37503610 NA -0.51 -7.89 -0.58 1.39e-12 Cognitive performance; TGCT cis rs62244186 0.659 rs4431151 chr3:44510906 G/C cg04389838 chr3:44770851 ZNF501 -0.38 -4.94 -0.41 2.5e-6 Depressive symptoms; TGCT cis rs77741769 0.571 rs7969140 chr12:121303626 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs7677751 0.806 rs7673027 chr4:55096180 T/A cg17187183 chr4:55093834 PDGFRA 0.55 7.06 0.54 1.05e-10 Corneal astigmatism; TGCT cis rs7312933 0.558 rs1796381 chr12:42842475 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.59 5.87 0.47 3.79e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4455778 0.538 rs34820160 chr7:49115948 C/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg06634786 chr22:41940651 POLR3H -0.89 -8.81 -0.62 9.46e-15 Vitiligo; TGCT cis rs3806843 0.576 rs246020 chr5:140334771 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7786808 0.712 rs2335167 chr7:158213948 A/C cg01191920 chr7:158217561 PTPRN2 -0.42 -6.67 -0.51 7.44e-10 Obesity-related traits; TGCT cis rs9403317 0.573 rs4896550 chr6:142029174 T/C cg15052665 chr6:141804349 NA -0.24 -4.46 -0.37 1.85e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9858542 0.903 rs17080528 chr3:49389842 C/T cg03060546 chr3:49711283 APEH -0.63 -5.47 -0.44 2.39e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6840360 0.557 rs4696261 chr4:152322659 C/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.68e-9 Intelligence (multi-trait analysis); TGCT cis rs7523273 0.548 rs2724381 chr1:207949017 T/C cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs4242434 0.672 rs6993302 chr8:22527457 T/C cg21658235 chr8:22456391 C8orf58 -0.45 -4.81 -0.4 4.37e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT trans rs1814175 0.586 rs10769603 chr11:49688837 T/C cg11707556 chr5:10655725 ANKRD33B -0.41 -9.51 -0.65 1.93e-16 Height; TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs3087591 0.879 rs4795591 chr17:29612410 C/A cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.21 -0.54 4.8e-11 Hip circumference; TGCT cis rs7617773 0.780 rs3731489 chr3:48228906 C/A cg11946769 chr3:48343235 NME6 0.77 6.73 0.52 5.53e-10 Coronary artery disease; TGCT cis rs765787 0.530 rs4238376 chr15:45541887 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs1580019 0.961 rs3801328 chr7:32496930 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.8 7.59 0.56 6.75e-12 Cognitive ability; TGCT cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg11644478 chr21:40555479 PSMG1 1.04 10.81 0.7 1.38e-19 Cognitive function; TGCT trans rs7618501 1.000 rs7618519 chr3:49772708 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs13256369 1.000 rs10095733 chr8:8574646 A/G cg17143192 chr8:8559678 CLDN23 0.63 5.93 0.47 2.8e-8 Obesity-related traits; TGCT trans rs7819412 0.623 rs7833435 chr8:10801137 A/G cg15556689 chr8:8085844 FLJ10661 -0.83 -7.45 -0.56 1.37e-11 Triglycerides; TGCT cis rs7727544 0.547 rs10076758 chr5:131524299 A/G cg24060327 chr5:131705240 SLC22A5 -0.44 -4.5 -0.37 1.56e-5 Blood metabolite levels; TGCT trans rs561341 1.000 rs693116 chr17:30246124 C/T cg20587970 chr11:113659929 NA -1.04 -12.51 -0.75 9.9e-24 Hip circumference adjusted for BMI; TGCT cis rs710216 0.957 rs710215 chr1:43429105 T/C cg03128534 chr1:43423976 SLC2A1 0.59 4.55 0.38 1.28e-5 Red cell distribution width; TGCT cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg18252515 chr7:66147081 NA 1.22 7.33 0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs9860250 0.554 rs9825968 chr3:100790788 C/T cg05801080 chr3:100119813 LNP1;TOMM70A 0.54 4.45 0.37 1.89e-5 Optic disc area; TGCT cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs9467711 0.606 rs9358932 chr6:26362705 A/G cg16898833 chr6:26189333 HIST1H4D -1.09 -5.35 -0.43 4.15e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1857353 1.000 rs74089258 chr1:75925610 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg23758822 chr17:41437982 NA 0.71 6.77 0.52 4.56e-10 Menopause (age at onset); TGCT cis rs28489187 0.597 rs506082 chr1:85899215 A/C cg16011679 chr1:85725395 C1orf52 -0.49 -4.49 -0.37 1.61e-5 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs748404 0.631 rs4296223 chr15:43645246 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs709400 0.633 rs2296484 chr14:104003094 C/T cg12935359 chr14:103987150 CKB -0.37 -5.54 -0.45 1.73e-7 Body mass index; TGCT cis rs7439150 0.954 rs2227423 chr4:155492249 T/C cg22130008 chr4:155548532 NA -0.53 -6.61 -0.51 1e-9 Fibrinogen levels; TGCT cis rs1990950 0.716 rs6890442 chr5:156832251 A/G cg25387487 chr5:157003181 ADAM19 0.3 4.66 0.39 7.98e-6 Lung function (FEV1/FVC); TGCT cis rs6545883 0.965 rs6545872 chr2:61724568 G/A cg15711740 chr2:61764176 XPO1 -0.54 -4.95 -0.41 2.39e-6 Tuberculosis; TGCT cis rs9549367 0.577 rs3024718 chr13:113813853 C/T cg00898013 chr13:113819073 PROZ 0.55 6.65 0.51 8.31e-10 Platelet distribution width; TGCT cis rs1505368 0.543 rs13413590 chr2:213292329 C/T cg16329650 chr2:213403929 ERBB4 0.65 6.24 0.49 6.44e-9 Symmetrical dimethylarginine levels; TGCT cis rs7582180 0.629 rs2309798 chr2:100956949 G/A cg14675211 chr2:100938903 LONRF2 0.53 5.16 0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.829 rs12636030 chr3:49182237 A/G cg16497277 chr3:49208875 KLHDC8B -0.5 -4.55 -0.38 1.25e-5 Parkinson's disease; TGCT cis rs17221829 0.703 rs17818747 chr11:89373690 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs7666738 0.609 rs35214820 chr4:98864692 G/A cg18180107 chr4:99064573 C4orf37 0.56 4.7 0.39 6.68e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 1.000 rs2439841 chr15:43734749 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs9467711 0.606 rs34878490 chr6:26370572 C/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7829975 0.774 rs11249893 chr8:8700851 C/T cg08975724 chr8:8085496 FLJ10661 0.55 5.01 0.41 1.8e-6 Mood instability; TGCT cis rs7975161 0.521 rs4447242 chr12:104720708 T/G cg25273343 chr12:104657179 TXNRD1 -0.36 -5.0 -0.41 1.9e-6 Toenail selenium levels; TGCT cis rs7940866 0.834 rs10791108 chr11:130849354 T/A cg12179176 chr11:130786555 SNX19 0.62 5.92 0.47 2.9e-8 Schizophrenia; TGCT cis rs12049351 0.774 rs6668018 chr1:229629053 T/C cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs473651 0.935 rs520765 chr2:239354712 C/T cg21699342 chr2:239360505 ASB1 0.18 4.94 0.41 2.49e-6 Multiple system atrophy; TGCT cis rs7917772 0.582 rs10883736 chr10:104320029 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17253792 0.822 rs75509578 chr14:56133493 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs6684514 1.000 rs12024813 chr1:156224529 C/A cg16558208 chr1:156270281 VHLL 0.46 8.4 0.6 8.73e-14 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg09323728 chr8:95962352 TP53INP1 -0.51 -6.49 -0.5 1.89e-9 Type 2 diabetes; TGCT cis rs2066819 0.892 rs117305040 chr12:56657888 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs13082711 0.595 rs17681498 chr3:27331258 T/C cg02860705 chr3:27208620 NA 0.48 7.4 0.55 1.83e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7829975 0.606 rs11776838 chr8:8794801 C/T cg00184457 chr8:8946301 NA -0.25 -4.85 -0.4 3.64e-6 Mood instability; TGCT cis rs244731 0.959 rs10037110 chr5:176658066 A/T cg06060754 chr5:176797920 RGS14 -0.45 -6.34 -0.49 3.93e-9 Urate levels in lean individuals; TGCT cis rs2243480 1.000 rs2243480 chr7:65599196 C/T cg07424592 chr7:64974309 NA 1.21 6.64 0.51 8.78e-10 Diabetic kidney disease; TGCT cis rs11578119 0.866 rs12129359 chr1:170358043 A/G cg09767346 chr1:170501363 GORAB 0.61 4.58 0.38 1.1e-5 Male-pattern baldness; TGCT cis rs9549260 0.816 rs7334318 chr13:41217410 C/G cg21288729 chr13:41239152 FOXO1 0.99 10.37 0.68 1.56e-18 Red blood cell count; TGCT cis rs524023 0.957 rs538737 chr11:64355772 C/G cg07733098 chr11:64478343 NRXN2 -0.31 -4.7 -0.39 6.79e-6 Urate levels in obese individuals; TGCT cis rs9296092 0.560 rs9469506 chr6:33527897 A/G cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs3020736 0.500 rs5996110 chr22:42493767 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs986417 0.818 rs7156107 chr14:61059153 C/G cg27398547 chr14:60952738 C14orf39 -1.0 -8.02 -0.58 6.72e-13 Gut microbiota (bacterial taxa); TGCT cis rs7267979 0.903 rs2500423 chr20:25374882 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6840360 0.571 rs62327269 chr4:152527973 G/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs1215050 0.740 rs13134479 chr4:99067723 G/A cg17366294 chr4:99064904 C4orf37 0.58 6.15 0.48 9.93e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12286929 0.637 rs3802858 chr11:115078492 T/C cg04017736 chr11:115827165 NA 0.2 4.96 0.41 2.25e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2050392 0.965 rs2480279 chr10:30700032 C/T cg18806716 chr10:30721971 MAP3K8 -0.46 -5.37 -0.43 3.74e-7 Inflammatory bowel disease; TGCT cis rs6952808 0.693 rs10950413 chr7:1912988 A/G cg22963979 chr7:1858916 MAD1L1 -0.35 -5.12 -0.42 1.14e-6 Bipolar disorder and schizophrenia; TGCT cis rs9814567 1.000 rs9871305 chr3:134213538 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9549367 0.713 rs9549357 chr13:113860121 C/T cg00898013 chr13:113819073 PROZ -0.52 -6.98 -0.53 1.6e-10 Platelet distribution width; TGCT cis rs9467773 1.000 rs6456733 chr6:26566804 C/T cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs8177179 0.967 rs9820225 chr3:133449189 A/G cg24879335 chr3:133465180 TF 0.37 5.02 0.41 1.72e-6 Iron status biomarkers (transferrin levels); TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg19626725 chr5:178986131 RUFY1 0.5 6.38 0.5 3.15e-9 Lung cancer; TGCT cis rs1552244 0.554 rs6443275 chr3:10008819 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.3 -4.7 -0.39 6.82e-6 Alzheimer's disease; TGCT cis rs8013055 0.846 rs10152050 chr14:105984145 C/G cg19700328 chr14:106028568 NA -0.48 -5.12 -0.42 1.14e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs950169 0.959 rs12902070 chr15:84793558 T/C cg17173187 chr15:85201210 NMB 0.5 5.56 0.45 1.61e-7 Schizophrenia; TGCT cis rs7819412 0.703 rs2409713 chr8:11009797 C/T cg21775007 chr8:11205619 TDH -0.59 -5.35 -0.43 4.12e-7 Triglycerides; TGCT cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs4927850 1.000 rs7625570 chr3:195747398 A/G cg22891161 chr3:195456627 MUC20 -0.23 -5.23 -0.43 6.89e-7 Pancreatic cancer; TGCT cis rs853679 0.513 rs13437444 chr6:28070998 C/T cg12963246 chr6:28129442 ZNF389 0.52 4.49 0.37 1.63e-5 Depression; TGCT cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9430161 0.611 rs35033941 chr1:11034382 C/T cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs208520 0.690 rs207107 chr6:66794385 T/C cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs2594989 0.778 rs6801721 chr3:11470267 T/C cg00170343 chr3:11313890 ATG7 0.79 5.8 0.46 5.18e-8 Circulating chemerin levels; TGCT cis rs6570726 0.791 rs6900040 chr6:145893134 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2637266 0.739 rs2439580 chr10:78423214 T/G cg18941641 chr10:78392320 NA 0.38 4.57 0.38 1.15e-5 Pulmonary function; TGCT cis rs2456568 0.802 rs1108910 chr11:93629677 C/T cg26875233 chr11:93583750 C11orf90 0.49 6.25 0.49 6.16e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg11890956 chr21:40555474 PSMG1 -0.98 -9.91 -0.66 2.08e-17 Cognitive function; TGCT cis rs1371867 0.875 rs1962901 chr8:101326428 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT trans rs7618501 0.932 rs4855850 chr3:49761571 G/A cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs7027203 0.576 rs4424329 chr9:96560806 G/C cg14598338 chr9:96623480 NA 0.49 7.16 0.54 6.37e-11 DNA methylation (variation); TGCT cis rs7586879 0.639 rs2033653 chr2:25103446 C/T cg01884057 chr2:25150051 NA -0.32 -6.07 -0.48 1.46e-8 Body mass index; TGCT cis rs9810089 0.835 rs655836 chr3:136097576 T/C cg12473912 chr3:136751656 NA 0.35 4.98 0.41 2.11e-6 Gestational age at birth (child effect); TGCT cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg07092213 chr7:1199455 ZFAND2A -0.45 -4.86 -0.4 3.52e-6 Longevity;Endometriosis; TGCT cis rs1451375 0.669 rs10274172 chr7:50637575 G/A cg18232548 chr7:50535776 DDC -0.46 -7.1 -0.54 8.31e-11 Malaria; TGCT trans rs17780086 0.529 rs7406406 chr17:30220153 T/G cg20587970 chr11:113659929 NA -0.59 -8.98 -0.63 3.73e-15 Height; TGCT cis rs11874712 1.000 rs11872985 chr18:43686578 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.15 0.42 1.01e-6 Migraine - clinic-based; TGCT cis rs4788815 0.562 rs12926041 chr16:71978645 G/C cg06353428 chr16:71660113 MARVELD3 0.75 6.74 0.52 5.43e-10 Metabolite levels; TGCT cis rs7584330 0.666 rs72620819 chr2:238354982 C/T cg14458575 chr2:238380390 NA 0.56 8.18 0.59 2.85e-13 Prostate cancer; TGCT cis rs36051895 0.659 rs62541556 chr9:5049092 G/T cg02405213 chr9:5042618 JAK2 -0.74 -9.85 -0.66 2.89e-17 Pediatric autoimmune diseases; TGCT cis rs6542838 0.588 rs4851175 chr2:99530118 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.24 -0.43 6.76e-7 Fear of minor pain; TGCT cis rs2742417 1.000 rs2673038 chr3:45748632 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs4911259 0.513 rs6057665 chr20:31463460 A/G cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.87 0.4 3.38e-6 Prudent dietary pattern; TGCT cis rs295140 0.605 rs3739119 chr2:201194279 C/A cg23649088 chr2:200775458 C2orf69 -0.27 -4.49 -0.37 1.62e-5 QT interval; TGCT cis rs9467711 0.651 rs16891261 chr6:26062631 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.6 -4.67 -0.39 7.83e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2204008 0.692 rs11613378 chr12:38213138 T/A cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs7191700 1.000 rs7191700 chr16:11406803 C/T cg00044050 chr16:11439710 C16orf75 0.74 6.7 0.52 6.59e-10 Multiple sclerosis; TGCT cis rs782590 0.774 rs782630 chr2:55899425 T/C cg03859395 chr2:55845619 SMEK2 0.85 9.64 0.65 9.63e-17 Metabolic syndrome; TGCT cis rs10504229 1.000 rs72652905 chr8:58188355 A/G cg08280861 chr8:58055591 NA 0.34 4.62 0.38 9.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs3008870 0.959 rs2815353 chr1:67483372 A/G cg03991309 chr1:68237761 GNG12 0.27 4.49 0.37 1.6e-5 Lymphocyte percentage of white cells; TGCT cis rs433598 0.828 rs163270 chr16:20675829 G/A cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -5.29 -0.43 5.36e-7 Schizophrenia; TGCT cis rs7681440 0.904 rs6817001 chr4:90766019 C/T cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg13393036 chr8:95962371 TP53INP1 -0.65 -8.88 -0.62 6.27e-15 Type 2 diabetes; TGCT cis rs644799 0.932 rs523934 chr11:95641775 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.71 7.54 0.56 8.81e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4727027 0.870 rs62507485 chr7:148764182 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.97 0.41 2.22e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2456568 0.867 rs2462744 chr11:93682913 G/A cg16099599 chr11:93583650 C11orf90 -0.39 -4.69 -0.39 7.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1215050 0.740 rs783941 chr4:99008235 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -5.03 -0.41 1.69e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7412746 0.658 rs7528773 chr1:150915875 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs2288884 0.806 rs17779439 chr19:52583991 G/T cg13540795 chr19:52551618 ZNF432 -0.61 -5.28 -0.43 5.48e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs17331151 0.573 rs2276818 chr3:52864635 A/G cg07884673 chr3:53033167 SFMBT1 0.49 5.66 0.45 1.01e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs849210 0.517 rs13022810 chr2:206181237 A/G cg11793701 chr2:206547163 NRP2 -0.54 -4.49 -0.37 1.62e-5 Tonsillectomy; TGCT cis rs7917772 0.604 rs10883756 chr10:104400112 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.26 -0.43 6.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg22907277 chr7:1156413 C7orf50 0.19 4.5 0.37 1.55e-5 Longevity;Endometriosis; TGCT cis rs7523273 0.626 rs2466572 chr1:207934487 A/C cg22525895 chr1:207977042 MIR29B2 0.46 6.75 0.52 5.11e-10 Schizophrenia; TGCT cis rs9467711 0.606 rs9393706 chr6:26361500 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4711350 0.723 rs549652 chr6:33686103 G/A cg00334056 chr6:33755658 LEMD2 0.34 4.57 0.38 1.19e-5 Schizophrenia; TGCT trans rs7618501 0.966 rs13085679 chr3:49869631 G/A cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.08e-30 Intelligence (multi-trait analysis); TGCT cis rs4566357 0.595 rs6707286 chr2:227911400 A/G cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.92e-7 Coronary artery disease; TGCT cis rs854765 0.551 rs8070748 chr17:17859421 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs7258465 1.000 rs271623 chr19:18628947 A/G cg06462663 chr19:18546047 ISYNA1 0.21 5.01 0.41 1.82e-6 Breast cancer; TGCT cis rs1691799 0.899 rs1168327 chr12:66728842 G/A cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.77e-9 White blood cell count (basophil); TGCT cis rs2153535 0.601 rs9328487 chr6:8529378 G/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9905704 0.647 rs12943705 chr17:57097047 T/C cg12560992 chr17:57184187 TRIM37 -0.62 -5.52 -0.44 1.9e-7 Testicular germ cell tumor; TGCT cis rs751728 1.000 rs751728 chr6:33764033 C/T cg00334056 chr6:33755658 LEMD2 -0.25 -4.52 -0.38 1.45e-5 Crohn's disease; TGCT cis rs9905704 0.647 rs6503892 chr17:57067086 G/A cg12560992 chr17:57184187 TRIM37 0.58 5.03 0.41 1.68e-6 Testicular germ cell tumor; TGCT cis rs7086627 0.515 rs10887894 chr10:82209952 A/G cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs9868809 0.772 rs73078349 chr3:48688114 G/A cg07636037 chr3:49044803 WDR6 -0.99 -4.44 -0.37 1.96e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs734999 0.588 rs3001837 chr1:2532506 G/A cg18854424 chr1:2615690 NA -0.46 -5.28 -0.43 5.53e-7 Ulcerative colitis; TGCT cis rs9583531 0.891 rs3742182 chr13:111375132 C/T cg24331049 chr13:111365604 ING1 0.77 5.42 0.44 3.05e-7 Coronary artery disease; TGCT cis rs1894292 0.527 rs12504448 chr4:74369406 G/A cg05868023 chr4:75230803 EREG -0.52 -4.64 -0.38 8.72e-6 Prostate cancer; TGCT trans rs6089829 0.925 rs6122087 chr20:61664553 T/C cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs523522 0.926 rs10774555 chr12:120971978 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs459571 0.959 rs461462 chr9:136911272 C/T cg13789015 chr9:136890014 NCRNA00094 0.39 6.81 0.52 3.72e-10 Platelet distribution width; TGCT cis rs7267979 0.966 rs4815425 chr20:25398876 G/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs473651 0.935 rs508483 chr2:239339709 T/C cg21699342 chr2:239360505 ASB1 0.18 4.78 0.39 4.79e-6 Multiple system atrophy; TGCT cis rs72781680 1.000 rs963725 chr2:24148231 T/C cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs7674212 0.541 rs11727498 chr4:104100987 C/T cg16532752 chr4:104119610 CENPE -0.58 -5.37 -0.43 3.66e-7 Type 2 diabetes; TGCT cis rs11190604 1.000 rs2495737 chr10:102338344 T/C cg23241863 chr10:102295624 HIF1AN 0.67 4.96 0.41 2.29e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9913156 0.793 rs9436 chr17:4574751 T/A cg00122941 chr17:4613640 ARRB2 0.88 7.51 0.56 1.03e-11 Lymphocyte counts; TGCT cis rs514406 1.000 rs514406 chr1:53330458 A/G cg22166914 chr1:53195759 ZYG11B 0.4 5.03 0.41 1.69e-6 Monocyte count; TGCT cis rs79349575 0.783 rs12601858 chr17:47017477 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT trans rs10506458 0.834 rs58821476 chr12:63389425 T/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.54 -0.56 8.62e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs2760061 0.598 rs590657 chr1:228117581 A/C cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs2560966 1.000 rs1171098 chr19:48531518 G/T cg17660703 chr19:48964810 KCNJ14 -0.35 -4.52 -0.38 1.41e-5 Intelligence; TGCT cis rs2153535 0.580 rs5001324 chr6:8451604 A/T cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs1348850 0.914 rs9789582 chr2:178330173 C/G cg22681709 chr2:178499509 PDE11A -0.36 -4.75 -0.39 5.6e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs13102973 0.899 rs4479760 chr4:135867474 T/C cg14419869 chr4:135874104 NA 0.24 4.46 0.37 1.83e-5 Subjective well-being; TGCT cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs11785400 0.762 rs1137522 chr8:143739020 A/C cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg00684032 chr4:1343700 KIAA1530 0.22 4.85 0.4 3.69e-6 Obesity-related traits; TGCT cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs9611565 0.608 rs2003816 chr22:42095140 T/G cg03806693 chr22:41940476 POLR3H 0.96 9.69 0.66 7.24e-17 Vitiligo; TGCT cis rs1568889 1.000 rs7102106 chr11:28343953 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.8 0.62 9.95e-15 Bipolar disorder; TGCT cis rs854765 0.663 rs6502618 chr17:17746741 A/G cg04398451 chr17:18023971 MYO15A 0.3 4.6 0.38 1.04e-5 Total body bone mineral density; TGCT cis rs2721195 0.719 rs4925812 chr8:145808035 C/T cg11211951 chr8:145729740 GPT 0.25 5.55 0.45 1.65e-7 Age at first birth; TGCT cis rs7178572 0.568 rs11858641 chr15:77585820 C/T cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs6912958 0.559 rs242280 chr6:88048714 G/A cg04972856 chr6:88032051 C6orf162;GJB7 0.4 4.71 0.39 6.65e-6 Monocyte percentage of white cells; TGCT cis rs7027203 0.576 rs4415381 chr9:96554603 A/G cg14598338 chr9:96623480 NA 0.49 7.16 0.54 6.37e-11 DNA methylation (variation); TGCT cis rs9372498 0.505 rs62422248 chr6:118987610 T/C cg07617317 chr6:118971624 C6orf204 0.49 5.14 0.42 1.02e-6 Diastolic blood pressure; TGCT cis rs1670533 1.000 rs6599279 chr4:1058833 G/A cg27284194 chr4:1044797 NA 0.68 5.88 0.47 3.56e-8 Recombination rate (females); TGCT cis rs10751667 0.666 rs11246358 chr11:967349 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.11 -0.59 4.15e-13 Alzheimer's disease (late onset); TGCT cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs3617 0.599 rs12487379 chr3:52895785 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.49 4.68 0.39 7.45e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9868809 0.772 rs9812200 chr3:48695667 A/G cg00383909 chr3:49044727 WDR6 -0.77 -4.84 -0.4 3.75e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7621025 0.500 rs4678275 chr3:136653683 C/T cg15507776 chr3:136538369 TMEM22 0.63 5.91 0.47 3.1e-8 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs9818758 0.607 rs13087930 chr3:48961726 A/G cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs611744 0.967 rs653633 chr8:109196151 T/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs801193 0.660 rs1962050 chr7:66240008 C/T cg11764359 chr7:65958608 NA -0.58 -5.22 -0.42 7.37e-7 Aortic root size; TGCT cis rs6835098 0.816 rs13111572 chr4:174159788 G/A cg08422745 chr4:174089978 GALNT7 0.93 10.32 0.68 2.06e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs1008375 0.806 rs13139898 chr4:17706928 T/G cg10189774 chr4:17578691 LAP3 -0.53 -4.7 -0.39 6.86e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs66573146 0.831 rs67315413 chr4:6987910 T/C cg05069807 chr4:6945702 TBC1D14 0.31 4.83 0.4 3.91e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs524281 0.861 rs7937281 chr11:65950074 T/C cg00563793 chr11:65837595 PACS1 0.57 5.03 0.41 1.68e-6 Electroencephalogram traits; TGCT cis rs909002 0.800 rs10914459 chr1:32096918 T/C cg11573219 chr1:32083031 HCRTR1 -0.43 -5.6 -0.45 1.33e-7 Intelligence (multi-trait analysis); TGCT cis rs826838 0.935 rs3886109 chr12:39189243 C/T cg13010199 chr12:38710504 ALG10B 0.77 6.09 0.48 1.31e-8 Heart rate; TGCT cis rs7412746 0.658 rs8444 chr1:150938571 G/A cg09365446 chr1:150670422 GOLPH3L 0.35 4.81 0.4 4.36e-6 Melanoma; TGCT cis rs4891159 0.757 rs11665518 chr18:74147054 C/T cg24786174 chr18:74118243 ZNF516 -0.54 -7.25 -0.55 4.01e-11 Longevity; TGCT cis rs9534288 0.763 rs9534273 chr13:46566988 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.63 -0.57 5.32e-12 Blood protein levels; TGCT cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2692947 0.589 rs810057 chr2:97015073 T/C cg23100626 chr2:96804247 ASTL 0.44 5.47 0.44 2.42e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7223966 1.000 rs6504170 chr17:61709168 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.59 0.38 1.05e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9400467 0.537 rs449308 chr6:111480395 A/C cg15721981 chr6:111408429 SLC16A10 -0.71 -4.6 -0.38 1.03e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs317689 0.680 rs315140 chr12:69790780 A/T cg11871910 chr12:69753446 YEATS4 0.54 4.6 0.38 1.02e-5 Response to diuretic therapy; TGCT cis rs11650494 0.901 rs74659133 chr17:47336931 C/T cg08112188 chr17:47440006 ZNF652 1.06 5.45 0.44 2.65e-7 Prostate cancer; TGCT cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg11890956 chr21:40555474 PSMG1 -1.03 -11.93 -0.73 2.49e-22 Cognitive function; TGCT cis rs782590 0.967 rs782592 chr2:55843875 T/A cg18811423 chr2:55921094 PNPT1 0.62 5.71 0.46 7.82e-8 Metabolic syndrome; TGCT cis rs77741769 0.571 rs11065282 chr12:121264415 G/T cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.58e-5 Mean corpuscular volume; TGCT cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs7647973 0.626 rs6809879 chr3:49834571 A/G cg03060546 chr3:49711283 APEH -0.63 -5.63 -0.45 1.12e-7 Menarche (age at onset); TGCT cis rs7447593 0.666 rs10866705 chr5:176801131 G/T cg16006841 chr5:176797999 RGS14 -0.65 -9.0 -0.63 3.34e-15 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs7192750 0.586 rs4788585 chr16:71993638 A/G cg06353428 chr16:71660113 MARVELD3 0.78 6.37 0.5 3.42e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg21672276 chr3:44754072 ZNF502 -0.45 -4.96 -0.41 2.25e-6 Depressive symptoms; TGCT cis rs6912958 0.559 rs242267 chr6:88061837 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.43 -5.7 -0.46 8.46e-8 Monocyte percentage of white cells; TGCT cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg19318889 chr4:1322082 MAEA 0.19 5.08 0.41 1.37e-6 Obesity-related traits; TGCT trans rs2727020 0.553 rs10839295 chr11:49527345 A/C cg15704280 chr7:45808275 SEPT13 -0.61 -6.81 -0.52 3.77e-10 Coronary artery disease; TGCT cis rs459571 1.000 rs459571 chr9:136912626 C/T cg14405625 chr9:136855902 VAV2 -0.32 -4.68 -0.39 7.28e-6 Platelet distribution width; TGCT cis rs9926296 0.656 rs4522419 chr16:89853307 T/C cg04287289 chr16:89883240 FANCA 0.68 6.75 0.52 5.13e-10 Vitiligo; TGCT cis rs68170813 0.559 rs12537730 chr7:106844281 T/C cg02696742 chr7:106810147 HBP1 -0.67 -5.39 -0.44 3.44e-7 Coronary artery disease; TGCT cis rs67460515 0.892 rs11711413 chr3:160998910 C/G cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT trans rs2727020 0.658 rs7120136 chr11:49384358 A/C cg15704280 chr7:45808275 SEPT13 -0.74 -8.29 -0.6 1.55e-13 Coronary artery disease; TGCT cis rs12477438 0.798 rs10167015 chr2:99570707 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.81 -7.88 -0.58 1.46e-12 Chronic sinus infection; TGCT cis rs66573146 1.000 rs73202122 chr4:7005594 G/A cg05069807 chr4:6945702 TBC1D14 0.38 5.12 0.42 1.11e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6088580 0.634 rs6120644 chr20:33023810 G/A cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs35306767 0.761 rs1871621 chr10:1049596 C/T cg20503657 chr10:835505 NA 0.61 6.71 0.52 6.11e-10 Eosinophil percentage of granulocytes; TGCT cis rs711245 0.572 rs3821150 chr2:36795233 G/A cg10546459 chr2:36825355 FEZ2 0.58 4.91 0.4 2.76e-6 Height; TGCT cis rs7100689 0.598 rs35353819 chr10:82135737 A/G cg01528321 chr10:82214614 TSPAN14 0.79 7.51 0.56 1.02e-11 Post bronchodilator FEV1; TGCT cis rs12887734 0.524 rs4900599 chr14:104283444 G/T cg26031613 chr14:104095156 KLC1 -0.72 -6.2 -0.49 7.61e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9952991 0.883 rs11663253 chr18:12789556 A/G cg23544223 chr18:12777786 NA -0.6 -5.33 -0.43 4.57e-7 Inflammatory skin disease; TGCT cis rs11599315 0.507 rs12220555 chr10:1341858 C/T cg27336068 chr10:1336103 ADARB2 -0.34 -5.47 -0.44 2.41e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs7246657 0.663 rs10408619 chr19:38070474 C/T cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs13326165 0.760 rs3752819 chr3:52400740 G/C cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.36e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg07061783 chr6:25882402 NA -0.55 -5.19 -0.42 8.38e-7 Intelligence (multi-trait analysis); TGCT cis rs6088590 1.000 rs6120748 chr20:33458284 T/G cg24642439 chr20:33292090 TP53INP2 0.7 5.98 0.47 2.17e-8 Coronary artery disease; TGCT cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg03264133 chr6:25882463 NA -0.65 -6.05 -0.48 1.58e-8 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.541 rs1414352 chr6:8485547 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT trans rs561341 1.000 rs2470243 chr17:30290955 C/T cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs1865760 1.000 rs6910174 chr6:25904414 C/T cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs7607369 0.609 rs13391398 chr2:219282429 A/G cg02176678 chr2:219576539 TTLL4 0.47 6.46 0.5 2.19e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs2677744 1.000 rs2677744 chr15:91450441 A/G cg23684204 chr15:91497937 RCCD1 -0.33 -4.86 -0.4 3.52e-6 Attention deficit hyperactivity disorder; TGCT cis rs2658782 1.000 rs2658778 chr11:93148948 C/G cg15737290 chr11:93063684 CCDC67 0.85 5.67 0.45 9.66e-8 Pulmonary function decline; TGCT cis rs2228479 0.850 rs62056066 chr16:89906563 G/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs7944584 0.879 rs11039182 chr11:47346723 T/C cg20307385 chr11:47447363 PSMC3 0.78 7.39 0.55 1.87e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs992157 1.000 rs13003334 chr2:219124921 T/A cg00012203 chr2:219082015 ARPC2 0.77 8.2 0.59 2.56e-13 Colorectal cancer; TGCT cis rs7819412 0.595 rs4841500 chr8:10988275 A/G cg21775007 chr8:11205619 TDH -0.54 -5.0 -0.41 1.87e-6 Triglycerides; TGCT cis rs3771570 0.901 rs869943 chr2:242431585 C/G cg21155796 chr2:242212141 HDLBP 0.92 6.63 0.51 9.25e-10 Prostate cancer; TGCT cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.23e-17 Electroencephalogram traits; TGCT cis rs10927875 0.722 rs6696912 chr1:16338474 T/C cg22431228 chr1:16359049 CLCNKA -0.26 -4.91 -0.4 2.79e-6 Dilated cardiomyopathy; TGCT cis rs1488864 1.000 rs1488864 chr11:6342329 T/G cg12755421 chr11:6342214 PRKCDBP -0.57 -4.6 -0.38 1.02e-5 Smooth-surface caries; TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs1153858 1.000 rs67744121 chr15:45677237 C/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs9291683 0.595 rs10939665 chr4:10037628 T/C cg00071950 chr4:10020882 SLC2A9 0.68 8.83 0.62 8.22e-15 Bone mineral density; TGCT cis rs12477438 0.572 rs10170063 chr2:99655639 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs2455799 0.573 rs2455831 chr3:15751583 T/A cg16303742 chr3:15540471 COLQ -0.25 -4.68 -0.39 7.43e-6 Mean platelet volume; TGCT cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Vitiligo; TGCT trans rs2727020 0.704 rs2988340 chr11:49176057 C/T cg11707556 chr5:10655725 ANKRD33B -0.38 -7.66 -0.57 4.66e-12 Coronary artery disease; TGCT cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg08439880 chr3:133502540 NA -0.35 -6.94 -0.53 1.93e-10 Iron status biomarkers; TGCT cis rs1568889 0.941 rs35357280 chr11:28322745 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 6.53 0.51 1.55e-9 Bipolar disorder; TGCT cis rs6594499 0.872 rs10038058 chr5:110443281 A/G cg04022379 chr5:110408740 TSLP 0.44 4.74 0.39 5.65e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7909074 0.865 rs10900123 chr10:45376574 C/T cg05187965 chr10:45406764 TMEM72 -0.28 -5.9 -0.47 3.3e-8 Mean corpuscular volume; TGCT cis rs12950390 0.853 rs55745341 chr17:45855778 G/C cg24803719 chr17:45855879 NA -0.46 -4.75 -0.39 5.56e-6 IgG glycosylation; TGCT cis rs7178424 0.711 rs11635569 chr15:62213597 G/A cg00456672 chr15:62358751 C2CD4A -0.3 -4.47 -0.37 1.71e-5 Height; TGCT cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 7.09 0.54 8.96e-11 Prudent dietary pattern; TGCT cis rs13108904 0.650 rs3796618 chr4:1349602 T/A cg13395646 chr4:1353034 KIAA1530 -0.42 -5.36 -0.43 3.92e-7 Obesity-related traits; TGCT cis rs12451471 0.559 rs1042396 chr17:78084769 G/A cg06718696 chr17:78121285 EIF4A3 0.71 5.89 0.47 3.42e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs7552404 0.727 rs1159214 chr1:76317910 G/T cg22875332 chr1:76189707 ACADM -0.58 -6.24 -0.49 6.18e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3849570 0.576 rs4425286 chr3:81992365 G/A cg07356753 chr3:81810745 GBE1 -0.56 -4.67 -0.39 7.67e-6 Waist circumference;Body mass index; TGCT cis rs1059312 1.000 rs7302634 chr12:129279931 C/T cg09035930 chr12:129282057 SLC15A4 0.6 10.93 0.7 6.81e-20 Systemic lupus erythematosus; TGCT cis rs6714710 0.603 rs13008968 chr2:98435982 C/T cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7666738 0.861 rs28821920 chr4:98962743 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs3806843 0.518 rs173471 chr5:140335226 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs7208859 0.673 rs56146117 chr17:29153325 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.06 0.41 1.5e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7336332 0.941 rs9579097 chr13:28084337 C/T cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Weight; TGCT cis rs524281 0.861 rs10896095 chr11:65962560 A/G cg00563793 chr11:65837595 PACS1 0.54 4.74 0.39 5.86e-6 Electroencephalogram traits; TGCT cis rs514406 0.621 rs2003250 chr1:53196666 T/C cg22166914 chr1:53195759 ZYG11B -0.5 -9.42 -0.65 3.19e-16 Monocyte count; TGCT cis rs10782582 0.609 rs1689270 chr1:76390937 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.56 4.84 0.4 3.71e-6 Daytime sleep phenotypes; TGCT cis rs763014 0.898 rs1045277 chr16:633125 T/C cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs909002 0.849 rs2271933 chr1:32092525 C/T cg11573219 chr1:32083031 HCRTR1 0.47 6.08 0.48 1.37e-8 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs4587214 chr6:8454119 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.31e-6 Motion sickness; TGCT cis rs6754311 0.593 rs6755383 chr2:136416941 C/T cg07169764 chr2:136633963 MCM6 0.67 6.1 0.48 1.24e-8 Mosquito bite size; TGCT cis rs12367572 0.965 rs1506678 chr12:45249492 A/G cg04608330 chr12:45269318 NELL2 -0.61 -6.39 -0.5 2.98e-9 Gut microbiome composition (summer); TGCT cis rs96067 0.711 rs795047 chr1:36637708 C/T cg07093915 chr1:36184400 C1orf216 0.43 4.46 0.37 1.81e-5 Corneal structure; TGCT cis rs7267979 0.714 rs6132825 chr20:25238309 A/T cg03522245 chr20:25566470 NINL 0.51 4.89 0.4 3.08e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg11905131 chr22:24372483 LOC391322 -0.95 -11.13 -0.71 2.26e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2404602 0.647 rs4886837 chr15:77156417 A/G cg23625390 chr15:77176239 SCAPER -0.39 -5.04 -0.41 1.6e-6 Blood metabolite levels; TGCT cis rs2997447 0.723 rs56241003 chr1:26435919 C/T cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT cis rs10751667 1.000 rs10794349 chr11:945678 T/C cg06064525 chr11:970664 AP2A2 -0.33 -6.65 -0.51 8.39e-10 Alzheimer's disease (late onset); TGCT cis rs858239 0.601 rs28673077 chr7:23250854 C/T cg05602783 chr7:23145260 KLHL7 -0.73 -5.73 -0.46 7.15e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9926296 0.508 rs1558184 chr16:89842374 T/G cg27121462 chr16:89883253 FANCA 0.78 8.41 0.6 8.42e-14 Vitiligo; TGCT cis rs6964587 0.900 rs11984136 chr7:91766953 T/C cg17063962 chr7:91808500 NA 0.91 9.8 0.66 3.89e-17 Breast cancer; TGCT cis rs858239 0.601 rs2141307 chr7:23191424 G/C cg05602783 chr7:23145260 KLHL7 -0.69 -5.78 -0.46 5.68e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9902453 0.967 rs4473252 chr17:28454423 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs4819052 0.851 rs2838864 chr21:46711474 A/T cg02159808 chr21:46707872 POFUT2;LOC642852 -0.57 -4.76 -0.39 5.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2233152 0.572 rs10403040 chr19:41296046 A/T cg23743927 chr19:41304969 EGLN2 0.65 4.54 0.38 1.34e-5 Kawasaki disease; TGCT cis rs651907 0.535 rs4342086 chr3:101503765 G/A cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs941408 0.515 rs4624312 chr19:2774460 T/C cg06609049 chr19:2785107 THOP1 1.12 12.98 0.76 7.39e-25 Total cholesterol levels; TGCT cis rs597539 0.652 rs513359 chr11:68669496 A/T cg06028808 chr11:68637592 NA -0.52 -6.89 -0.53 2.46e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6074578 0.679 rs2298109 chr20:138148 C/T cg16931068 chr20:139680 DEFB127 0.29 5.06 0.41 1.46e-6 Hirschsprung disease; TGCT cis rs12971120 0.947 rs8084410 chr18:72168486 T/C cg26446133 chr18:72167187 CNDP2 -0.39 -7.53 -0.56 9.3e-12 Refractive error; TGCT cis rs6534347 0.551 rs10032644 chr4:123544074 T/A cg10583651 chr4:123538969 IL21 -0.32 -4.5 -0.37 1.54e-5 Type 1 diabetes; TGCT cis rs2721195 0.626 rs59464125 chr8:145857786 G/A cg15320075 chr8:145703422 NA -0.61 -5.66 -0.45 9.8e-8 Age at first birth; TGCT cis rs4747241 0.515 rs4554797 chr10:73988264 A/G cg09661010 chr10:73848153 SPOCK2 -0.41 -5.24 -0.43 6.81e-7 Heschl's gyrus morphology; TGCT cis rs12477438 0.501 rs7608938 chr2:99782226 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs9902453 0.817 rs12051834 chr17:28192785 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.62e-11 Coffee consumption (cups per day); TGCT cis rs17331151 0.505 rs7614424 chr3:52566354 C/T cg15956490 chr3:53032818 SFMBT1 0.7 5.14 0.42 1.02e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8078723 0.690 rs3785549 chr17:38149724 T/C cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs1205863 1.000 rs1205875 chr6:11945509 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs2467099 0.504 rs2608881 chr17:73936653 C/G cg10108402 chr17:73901394 MRPL38 -0.47 -4.6 -0.38 1.02e-5 Systolic blood pressure; TGCT cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs6988636 1.000 rs28694222 chr8:124195017 C/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs12908161 0.960 rs11633450 chr15:85307287 C/T cg17173187 chr15:85201210 NMB 0.61 6.23 0.49 6.75e-9 Schizophrenia; TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg14893161 chr1:205819251 PM20D1 0.66 10.91 0.7 7.77e-20 Menarche (age at onset); TGCT cis rs7772486 0.701 rs11155438 chr6:145950112 C/G cg23711669 chr6:146136114 FBXO30 0.92 10.45 0.68 1.03e-18 Lobe attachment (rater-scored or self-reported); TGCT trans rs1814175 0.645 rs1851849 chr11:50012164 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs11098499 0.722 rs10025925 chr4:120271744 A/T cg09307838 chr4:120376055 NA 0.56 5.48 0.44 2.26e-7 Corneal astigmatism; TGCT cis rs6570726 1.000 rs386678 chr6:145869010 A/G cg23711669 chr6:146136114 FBXO30 0.71 6.55 0.51 1.4e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6460942 0.558 rs4330594 chr7:12278615 G/A cg06484146 chr7:12443880 VWDE -0.53 -4.65 -0.39 8.3e-6 Coronary artery disease; TGCT cis rs7010267 0.668 rs4876876 chr8:119986235 T/C cg17171407 chr8:119960777 TNFRSF11B 0.32 6.05 0.48 1.62e-8 Total body bone mineral density (age 45-60); TGCT cis rs2456568 0.709 rs1546400 chr11:93639203 G/A cg26875233 chr11:93583750 C11orf90 0.47 6.01 0.48 1.9e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2046867 0.628 rs1393584 chr3:72917193 G/T cg25664220 chr3:72788482 NA -0.41 -5.61 -0.45 1.26e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg00024416 chr22:24240387 NA -0.25 -4.79 -0.39 4.74e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7017914 0.967 rs1838393 chr8:71702591 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.52 -4.8 -0.4 4.53e-6 Bone mineral density; TGCT cis rs9682041 1.000 rs57508070 chr3:170074374 C/A cg07589077 chr3:170072950 NA 0.32 4.83 0.4 3.88e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs6952808 0.531 rs3779003 chr7:2184902 C/T cg22963979 chr7:1858916 MAD1L1 -0.33 -5.38 -0.44 3.53e-7 Bipolar disorder and schizophrenia; TGCT cis rs9816226 0.618 rs869399 chr3:185826764 C/T cg00760338 chr3:185826511 ETV5 0.71 6.24 0.49 6.28e-9 Obesity;Body mass index; TGCT cis rs10875746 0.855 rs10875730 chr12:48427875 A/T cg20731937 chr12:48336164 NA 0.68 5.29 0.43 5.3e-7 Longevity (90 years and older); TGCT cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg26818010 chr10:134567672 INPP5A -0.39 -5.36 -0.43 3.97e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9831754 0.906 rs1588650 chr3:78410750 T/G cg06138941 chr3:78371609 NA -0.47 -5.01 -0.41 1.87e-6 Calcium levels; TGCT cis rs7769051 1.000 rs7769051 chr6:133146796 G/T cg07930552 chr6:133119739 C6orf192 0.94 4.99 0.41 1.98e-6 Type 2 diabetes nephropathy; TGCT cis rs7044106 0.791 rs10739572 chr9:123489815 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 7.55 0.56 8.22e-12 Hip circumference adjusted for BMI; TGCT cis rs7552404 0.696 rs10782602 chr1:76464261 T/C cg03433033 chr1:76189801 ACADM 0.76 7.05 0.54 1.09e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2251381 0.640 rs2183568 chr21:30484782 A/T cg08807101 chr21:30365312 RNF160 -0.51 -4.49 -0.37 1.6e-5 Selective IgA deficiency; TGCT cis rs10782582 0.593 rs11576534 chr1:76112751 C/T cg22875332 chr1:76189707 ACADM -0.52 -6.05 -0.48 1.56e-8 Daytime sleep phenotypes; TGCT cis rs7809950 0.817 rs17154091 chr7:107084790 T/C cg23024343 chr7:107201750 COG5 -0.48 -7.05 -0.54 1.08e-10 Coronary artery disease; TGCT cis rs1008375 0.932 rs2302389 chr4:17661889 T/C cg10189774 chr4:17578691 LAP3 0.49 4.44 0.37 2e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2228479 0.717 rs12917681 chr16:89810941 C/A cg26513180 chr16:89883248 FANCA 0.78 4.54 0.38 1.32e-5 Skin colour saturation; TGCT cis rs9549260 0.753 rs9549243 chr13:41217205 G/A cg21288729 chr13:41239152 FOXO1 0.65 4.59 0.38 1.09e-5 Red blood cell count; TGCT cis rs9393777 0.513 rs9368447 chr6:26646674 A/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.904 rs2338797 chr17:37548241 G/A cg15445000 chr17:37608096 MED1 -0.33 -4.7 -0.39 6.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs344364 0.511 rs56077812 chr16:1948870 T/G cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs8177179 0.967 rs4443173 chr3:133439378 A/G cg24879335 chr3:133465180 TF 0.36 4.82 0.4 4.13e-6 Iron status biomarkers (transferrin levels); TGCT cis rs1018836 0.818 rs2285232 chr8:91546162 C/G cg16814680 chr8:91681699 NA -0.75 -7.78 -0.57 2.41e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs56104184 0.668 rs73063523 chr19:49408943 T/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4455778 0.543 rs4132419 chr7:49066633 A/G cg26309511 chr7:48887640 NA 0.51 6.63 0.51 9.47e-10 Lung cancer in never smokers; TGCT cis rs3733585 0.605 rs4697708 chr4:10121189 A/G cg11266682 chr4:10021025 SLC2A9 -0.56 -6.5 -0.5 1.76e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3821902 0.646 rs58627691 chr3:64015548 T/C cg22134162 chr3:63841271 THOC7 -0.32 -4.85 -0.4 3.7e-6 Breast cancer; TGCT trans rs2727020 0.823 rs7102374 chr11:49261795 G/A cg15704280 chr7:45808275 SEPT13 0.73 8.14 0.59 3.47e-13 Coronary artery disease; TGCT cis rs270601 0.690 rs162907 chr5:131580152 A/G cg22598563 chr5:131563921 P4HA2 0.27 4.5 0.37 1.56e-5 Acylcarnitine levels; TGCT cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs12681287 0.752 rs10112123 chr8:87302328 T/C cg27223183 chr8:87520930 FAM82B -0.82 -5.86 -0.47 3.98e-8 Caudate activity during reward; TGCT cis rs9796 0.558 rs8043253 chr15:41503730 C/T cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.27 -0.55 3.55e-11 Menopause (age at onset); TGCT cis rs314370 0.855 rs17883557 chr7:100494949 G/T cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs4272321 1 rs4272321 chr7:157951835 A/G cg02617428 chr7:158030585 PTPRN2 0.35 5.31 0.43 4.85e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7929679 0.846 rs1858169 chr11:34813187 G/T cg18414381 chr11:34642885 EHF -0.23 -4.51 -0.38 1.47e-5 Chronic obstructive pulmonary disease-related biomarkers;Lung disease severity in cystic fibrosis; TGCT cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.57e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.505 rs405208 chr1:53176674 C/T cg24675658 chr1:53192096 ZYG11B -0.78 -9.29 -0.64 6.63e-16 Monocyte count; TGCT cis rs908922 0.676 rs2282296 chr1:152487979 C/T cg20991723 chr1:152506922 NA 0.47 6.71 0.52 6.16e-10 Hair morphology; TGCT cis rs4478858 0.684 rs4949369 chr1:31723845 T/A cg00250761 chr1:31883323 NA -0.27 -4.96 -0.41 2.28e-6 Alcohol dependence; TGCT cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg03517284 chr6:25882590 NA -0.46 -4.62 -0.38 9.63e-6 Height; TGCT cis rs2153535 0.580 rs6597330 chr6:8492076 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9467711 1.000 rs9467704 chr6:26319486 A/G cg02458000 chr6:26745757 NA 1.1 6.09 0.48 1.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs2718812 0.766 rs2589269 chr3:133409977 C/T cg08048268 chr3:133502702 NA 0.39 4.83 0.4 3.99e-6 Iron status biomarkers; TGCT cis rs9894429 0.624 rs9910935 chr17:79613949 T/C cg21028142 chr17:79581711 NPLOC4 0.28 6.12 0.48 1.13e-8 Eye color traits; TGCT cis rs904251 0.600 rs9380673 chr6:37415125 T/C cg08126542 chr6:37504118 NA -0.4 -5.72 -0.46 7.68e-8 Cognitive performance; TGCT cis rs9527 0.590 rs11191540 chr10:104822809 G/C cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT cis rs12530845 0.945 rs7799891 chr7:135322853 T/C cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs12681287 0.547 rs9942793 chr8:87509091 C/T cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs4478858 0.735 rs10798845 chr1:31822636 A/G cg07478791 chr1:31886160 SERINC2 0.48 4.84 0.4 3.72e-6 Alcohol dependence; TGCT cis rs453301 0.686 rs1045527 chr8:8890041 A/G cg15556689 chr8:8085844 FLJ10661 -0.62 -5.28 -0.43 5.57e-7 Joint mobility (Beighton score); TGCT cis rs1799949 0.965 rs8067269 chr17:41235799 C/T cg23758822 chr17:41437982 NA 0.61 5.86 0.47 3.83e-8 Menopause (age at onset); TGCT cis rs12142240 0.698 rs72677593 chr1:46824363 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs4788570 0.697 rs2173702 chr16:71812671 G/A cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs9486719 0.857 rs2983897 chr6:97033780 C/T cg18709589 chr6:96969512 KIAA0776 -0.73 -6.07 -0.48 1.43e-8 Migraine;Coronary artery disease; TGCT cis rs10193935 0.901 rs6544549 chr2:42693056 C/T cg27598129 chr2:42591480 NA 0.38 5.14 0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6088580 0.634 rs6059905 chr20:33126946 T/C cg08999081 chr20:33150536 PIGU 0.28 5.55 0.45 1.66e-7 Glomerular filtration rate (creatinine); TGCT cis rs6940638 0.531 rs12211984 chr6:26986054 G/C cg05738196 chr6:26577821 NA 0.49 4.77 0.39 4.98e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg22535103 chr8:58192502 C8orf71 0.4 4.71 0.39 6.66e-6 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.647 rs55778276 chr15:77136590 T/A cg22467129 chr15:76604101 ETFA 0.46 4.64 0.38 8.6e-6 Blood metabolite levels; TGCT cis rs35306767 0.668 rs72760914 chr10:1070952 A/G cg20503657 chr10:835505 NA 0.49 5.66 0.45 9.87e-8 Eosinophil percentage of granulocytes; TGCT cis rs362272 0.524 rs3129334 chr4:3368526 T/C cg22655196 chr4:3374909 RGS12 0.22 4.49 0.37 1.58e-5 Serum sulfate level; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs9467711 0.559 rs13208916 chr6:26601940 G/A cg16898833 chr6:26189333 HIST1H4D 1.01 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7726839 0.540 rs72705030 chr5:645562 C/T cg20362242 chr5:692897 TPPP 0.51 4.66 0.39 8.06e-6 Obesity-related traits; TGCT cis rs2562456 1.000 rs2562456 chr19:21666210 A/G cg01304269 chr19:21688519 ZNF429 0.57 4.76 0.39 5.32e-6 Pain; TGCT cis rs4631830 0.720 rs12412140 chr10:51503977 T/C cg10326726 chr10:51549505 MSMB 0.23 4.54 0.38 1.33e-5 Prostate-specific antigen levels; TGCT cis rs2456568 0.803 rs10765641 chr11:93640312 T/C cg16099599 chr11:93583650 C11orf90 -0.39 -4.78 -0.39 4.97e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4819052 0.851 rs3673 chr21:46681775 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.55 0.38 1.25e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1153858 1.000 rs66528868 chr15:45668547 A/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT trans rs1814175 0.712 rs9665784 chr11:50030617 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs7586879 0.598 rs6724772 chr2:25128730 T/C cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs763014 0.966 rs4984904 chr16:680809 C/G cg07343612 chr16:622815 PIGQ -0.42 -8.45 -0.6 6.8e-14 Height; TGCT cis rs11264213 0.591 rs274745 chr1:36538282 G/A cg27506609 chr1:36549197 TEKT2 -0.41 -4.7 -0.39 6.71e-6 Schizophrenia; TGCT cis rs2236918 0.710 rs1776159 chr1:242018583 C/G cg04158730 chr1:242011433 EXO1 0.59 5.53 0.44 1.78e-7 Menopause (age at onset); TGCT cis rs7539409 0.651 rs910182 chr1:84297117 A/G cg10977910 chr1:84465055 TTLL7 0.91 5.53 0.45 1.78e-7 Alzheimer's disease; TGCT cis rs42648 0.935 rs42651 chr7:89978590 A/G cg25739043 chr7:89950458 NA -0.67 -6.69 -0.52 6.69e-10 Homocysteine levels; TGCT cis rs6867032 1.000 rs4975796 chr5:2015520 A/T cg26168224 chr5:2018326 NA -0.43 -7.52 -0.56 9.44e-12 Gut microbiome composition (winter); TGCT cis rs11650494 0.908 rs8076023 chr17:47399633 C/G cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs16966142 0.786 rs2238533 chr16:89871344 T/C cg26513180 chr16:89883248 FANCA 0.89 5.45 0.44 2.62e-7 Caffeine consumption; TGCT cis rs2228479 0.850 rs17227057 chr16:89816333 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs4879913 0.801 rs7047816 chr9:35591632 G/T cg18130437 chr9:35658183 CCDC107;RMRP -0.5 -4.95 -0.41 2.38e-6 Electroencephalogram traits; TGCT cis rs10791097 0.694 rs2155749 chr11:130751094 G/T cg05962950 chr11:130786565 SNX19 0.91 11.68 0.72 1.01e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs28785552 0.897 rs7259466 chr19:53239369 G/A cg22067481 chr19:53234126 ZNF611 -0.49 -7.16 -0.54 6.29e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs6964587 0.967 rs6465340 chr7:91588664 G/A cg17063962 chr7:91808500 NA 0.88 9.63 0.65 1.02e-16 Breast cancer; TGCT cis rs7267979 1.000 rs6050631 chr20:25431749 C/T cg03522245 chr20:25566470 NINL 0.63 6.82 0.52 3.55e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2549003 1.000 rs2070728 chr5:131819977 C/T cg21138405 chr5:131827807 IRF1 0.19 4.79 0.4 4.64e-6 Asthma (sex interaction); TGCT cis rs548181 0.668 rs540555 chr11:125486848 T/C cg03464685 chr11:125439445 EI24 1.12 7.9 0.58 1.27e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7647973 0.593 rs28535523 chr3:49848414 C/T cg05785598 chr3:49045655 WDR6 -0.43 -5.28 -0.43 5.5e-7 Menarche (age at onset); TGCT cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.95 -0.53 1.82e-10 Prostate cancer; TGCT cis rs4788570 0.537 rs12149254 chr16:71458851 G/A cg06353428 chr16:71660113 MARVELD3 -1.25 -8.03 -0.58 6.54e-13 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs4595586 0.525 rs2892450 chr12:39363678 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT trans rs7618501 1.000 rs7374277 chr3:49784777 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs8072100 0.967 rs7221548 chr17:45582952 T/C cg08085267 chr17:45401833 C17orf57 0.44 4.63 0.38 8.96e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs344364 0.511 rs2982455 chr16:1950498 T/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.11 -0.42 1.17e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs1552244 0.572 rs7645759 chr3:10157368 C/T cg00149659 chr3:10157352 C3orf10 1.13 7.38 0.55 2e-11 Alzheimer's disease; TGCT trans rs561341 0.769 rs12941700 chr17:30185022 A/G cg20587970 chr11:113659929 NA 0.84 8.42 0.6 7.76e-14 Hip circumference adjusted for BMI; TGCT cis rs1218582 0.772 rs4240874 chr1:154885779 C/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs4629710 0.592 rs1885641 chr6:131553986 A/G cg12606694 chr6:131520996 AKAP7 0.4 4.76 0.39 5.26e-6 Multiple myeloma (IgH translocation); TGCT trans rs4332037 0.539 rs11762545 chr7:2060775 C/T cg10840412 chr1:235813424 GNG4 0.94 6.84 0.52 3.21e-10 Bipolar disorder; TGCT cis rs7819412 0.838 rs4840544 chr8:10960572 C/T cg27411982 chr8:10470053 RP1L1 -0.22 -4.81 -0.4 4.38e-6 Triglycerides; TGCT cis rs9487051 0.872 rs1111865 chr6:109610863 A/G cg01475377 chr6:109611718 NA 0.29 4.57 0.38 1.14e-5 Reticulocyte fraction of red cells; TGCT cis rs9473924 0.542 rs13195969 chr6:50814627 C/A cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs4689388 0.816 rs13147655 chr4:6293474 A/G cg25554036 chr4:6271136 WFS1 0.52 7.12 0.54 7.56e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7833790 0.632 rs6415653 chr8:82702536 A/G cg17211192 chr8:82754475 SNX16 -0.9 -7.85 -0.58 1.71e-12 Diastolic blood pressure; TGCT cis rs13256369 0.802 rs12681326 chr8:8566389 G/A cg17143192 chr8:8559678 CLDN23 0.57 5.4 0.44 3.2e-7 Obesity-related traits; TGCT cis rs6690583 0.623 rs74689037 chr1:85439268 C/T cg20280350 chr1:85513789 MCOLN3 -0.67 -4.5 -0.37 1.52e-5 Serum sulfate level; TGCT cis rs6988636 0.710 rs17316158 chr8:124157607 A/C cg23067535 chr8:124195133 FAM83A -0.35 -4.71 -0.39 6.44e-6 Urinary uromodulin levels; TGCT cis rs4700695 0.719 rs27080 chr5:65442271 A/G cg21114390 chr5:65439923 SFRS12 -0.83 -7.19 -0.54 5.27e-11 Facial morphology (factor 19); TGCT cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs75229567 0.618 rs75389984 chr12:70212879 A/G cg10114359 chr12:70132523 RAB3IP 1.38 6.71 0.52 6.19e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs17331151 0.573 rs77223362 chr3:52865125 G/A cg27565382 chr3:53032988 SFMBT1 0.47 5.96 0.47 2.42e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10986311 0.649 rs10818936 chr9:127006346 C/G cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.54 -0.38 1.3e-5 Vitiligo; TGCT cis rs1062177 0.756 rs2915817 chr5:151115517 T/C cg12924095 chr5:151150029 G3BP1 -0.34 -4.87 -0.4 3.3e-6 Preschool internalizing problems; TGCT cis rs9910055 0.509 rs9916444 chr17:42313512 C/G cg19774624 chr17:42201019 HDAC5 -0.69 -7.14 -0.54 6.91e-11 Total body bone mineral density; TGCT cis rs12134133 1.000 rs6684804 chr1:207439015 C/T cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg02675527 chr2:114030824 PAX8;LOC440839 -0.47 -5.71 -0.46 7.9e-8 Lymphocyte counts; TGCT cis rs11031096 0.502 rs720571 chr11:4001328 G/T cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs992157 0.798 rs10932772 chr2:219177148 C/T cg00012203 chr2:219082015 ARPC2 0.76 7.6 0.56 6.44e-12 Colorectal cancer; TGCT cis rs7959452 0.558 rs1478464 chr12:69779789 G/C cg11871910 chr12:69753446 YEATS4 0.83 9.03 0.63 2.79e-15 Blood protein levels; TGCT cis rs2456568 0.709 rs12806128 chr11:93634972 C/T cg17595323 chr11:93583763 C11orf90 0.47 6.22 0.49 6.86e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs3780486 0.801 rs10971424 chr9:33138775 T/C cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT trans rs2727020 0.563 rs10769582 chr11:49474040 T/C cg03929089 chr4:120376271 NA -0.77 -9.19 -0.64 1.15e-15 Coronary artery disease; TGCT cis rs60843830 0.964 rs62114538 chr2:256116 G/T cg00108164 chr2:264199 ACP1;SH3YL1 0.67 6.32 0.49 4.25e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2120019 1.000 rs7173833 chr15:75369618 C/T cg17294928 chr15:75287854 SCAMP5 -0.93 -7.16 -0.54 6.33e-11 Blood trace element (Zn levels); TGCT cis rs7044106 0.718 rs1981021 chr9:123388393 T/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.58 0.51 1.19e-9 Hip circumference adjusted for BMI; TGCT cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg10802521 chr3:52805072 NEK4 -0.7 -8.52 -0.61 4.47e-14 Bipolar disorder; TGCT cis rs1865760 0.566 rs9379825 chr6:26083871 C/A cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs11910985 1.000 rs11910985 chr21:48042766 C/T cg17243659 chr21:48055224 PRMT2 1.26 6.43 0.5 2.45e-9 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs8177253 0.896 rs34252038 chr3:133490621 G/T cg16414030 chr3:133502952 NA -0.61 -9.83 -0.66 3.35e-17 Iron status biomarkers; TGCT cis rs1696756 1.000 rs1696756 chr17:77827973 C/T cg00646381 chr17:77835854 NA 0.44 7.51 0.56 1.02e-11 Glucocorticoid-induced osteonecrosis (age 10 years and older); TGCT cis rs6866344 0.697 rs11748497 chr5:178130012 C/G cg10224037 chr5:178157518 ZNF354A 0.93 8.22 0.59 2.25e-13 Neutrophil percentage of white cells; TGCT cis rs7178572 0.568 rs1823100 chr15:77402744 C/T cg15453836 chr15:77711506 NA -0.4 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg25036284 chr2:26402008 FAM59B 0.72 5.06 0.41 1.44e-6 Gut microbiome composition (summer); TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg11235426 chr6:292522 DUSP22 -0.69 -6.94 -0.53 1.93e-10 Menopause (age at onset); TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg24675658 chr1:53192096 ZYG11B -0.69 -8.17 -0.59 3.05e-13 Monocyte count; TGCT trans rs28595532 0.748 rs67928655 chr4:119336525 C/A cg26518628 chr1:97050305 NA -0.56 -6.79 -0.52 4.19e-10 Cannabis dependence symptom count; TGCT cis rs9549260 0.753 rs9549246 chr13:41220755 G/A cg21288729 chr13:41239152 FOXO1 0.67 4.68 0.39 7.31e-6 Red blood cell count; TGCT cis rs1991651 0.578 rs13259086 chr8:10490218 G/C cg27411982 chr8:10470053 RP1L1 0.22 5.03 0.41 1.66e-6 Granulocyte count;Neutrophil count;Myeloid white cell count;Sum basophil neutrophil counts;Sum neutrophil eosinophil counts; TGCT cis rs9733 0.596 rs12086630 chr1:150650955 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs597539 0.731 rs664229 chr11:68624483 C/G cg06028808 chr11:68637592 NA 0.55 6.88 0.53 2.61e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs769267 0.930 rs4808208 chr19:19650096 A/G cg08509172 chr19:19383838 TM6SF2 -0.35 -4.49 -0.37 1.62e-5 Tonsillectomy; TGCT cis rs7829975 0.560 rs17154599 chr8:8551418 C/T cg17143192 chr8:8559678 CLDN23 -0.5 -5.18 -0.42 8.74e-7 Mood instability; TGCT cis rs12908161 1.000 rs36033486 chr15:85319692 A/G cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.04e-8 Schizophrenia; TGCT cis rs7666738 0.753 rs7659724 chr4:98944063 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9913156 0.589 rs7213481 chr17:4547906 C/T cg23387401 chr17:4582204 PELP1 0.32 4.75 0.39 5.42e-6 Lymphocyte counts; TGCT cis rs2447097 0.904 rs2447098 chr17:2277720 C/A cg27406664 chr17:2294951 MNT 0.26 5.22 0.42 7.44e-7 Autism spectrum disorder; TGCT cis rs16867321 0.639 rs12466864 chr2:181441417 C/G cg23363182 chr2:181467187 NA 0.42 6.22 0.49 7.03e-9 Obesity; TGCT cis rs7647973 1.000 rs7619789 chr3:49476263 T/C cg07636037 chr3:49044803 WDR6 0.64 5.26 0.43 6.12e-7 Menarche (age at onset); TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg09177884 chr7:1199841 ZFAND2A -0.66 -6.62 -0.51 9.87e-10 Longevity;Endometriosis; TGCT cis rs35883536 0.647 rs2809790 chr1:101040461 C/T cg06223162 chr1:101003688 GPR88 0.42 8.0 0.58 7.5e-13 Monocyte count; TGCT cis rs11648796 0.721 rs3169403 chr16:769247 G/A cg27144592 chr16:783916 NARFL 0.43 5.82 0.46 4.73e-8 Height; TGCT cis rs11676348 0.811 rs4674255 chr2:218987325 C/T cg00012203 chr2:219082015 ARPC2 -0.51 -4.85 -0.4 3.6e-6 Ulcerative colitis; TGCT cis rs422249 0.512 rs174583 chr11:61609750 A/G cg19610905 chr11:61596333 FADS2 0.87 8.05 0.59 5.89e-13 Trans fatty acid levels; TGCT trans rs1814175 0.565 rs4881721 chr11:49761851 G/A cg15704280 chr7:45808275 SEPT13 -0.58 -6.7 -0.52 6.48e-10 Height; TGCT cis rs9517320 0.534 rs9556963 chr13:99157026 G/A cg20487152 chr13:99095054 FARP1 -0.24 -4.64 -0.38 8.83e-6 Longevity; TGCT cis rs73198271 0.960 rs73198290 chr8:8616009 A/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.79 -0.39 4.72e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs13040088 1.000 rs13040088 chr20:61549202 A/G cg23096297 chr20:61557774 DIDO1 1.19 9.82 0.66 3.46e-17 Menopause (age at onset); TGCT cis rs114540395 0.777 rs17760556 chr10:103138615 G/A cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs6860806 0.531 rs270612 chr5:131637338 G/A cg24060327 chr5:131705240 SLC22A5 -0.73 -7.65 -0.57 4.87e-12 Breast cancer; TGCT cis rs769267 0.930 rs4808203 chr19:19568659 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.67 5.45 0.44 2.66e-7 Tonsillectomy; TGCT cis rs2760061 0.819 rs708111 chr1:228191365 G/A cg02753203 chr1:228287806 NA 0.3 5.71 0.46 7.95e-8 Diastolic blood pressure; TGCT cis rs79149102 0.579 rs6495142 chr15:75320166 C/T cg09165964 chr15:75287851 SCAMP5 -1.05 -5.73 -0.46 7.26e-8 Lung cancer; TGCT cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT trans rs1499614 1.000 rs1638731 chr7:66144679 C/T cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs9513593 1.000 rs35912802 chr13:99886236 A/C cg21788972 chr13:99853209 UBAC2 0.59 4.73 0.39 6.13e-6 Psoriasis; TGCT cis rs10791097 0.703 rs11222360 chr11:130730871 C/T cg12179176 chr11:130786555 SNX19 0.76 9.14 0.63 1.54e-15 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11674184 0.525 rs4669755 chr2:11748585 A/C cg07314298 chr2:11723111 GREB1 0.36 6.44 0.5 2.34e-9 Endometriosis; TGCT cis rs12049351 0.665 rs12035203 chr1:229642517 T/C cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs2346177 0.875 rs1447565 chr2:46643682 T/A cg26688816 chr2:46740690 ATP6V1E2 -0.41 -4.53 -0.38 1.38e-5 HDL cholesterol; TGCT cis rs815815 0.608 rs6751198 chr2:47396274 C/T cg27223769 chr2:47403360 CALM2 -0.58 -5.25 -0.43 6.34e-7 Dialysis-related mortality; TGCT cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg03806693 chr22:41940476 POLR3H 1.08 11.98 0.73 1.9e-22 Vitiligo; TGCT cis rs11623869 0.772 rs12587310 chr14:103907286 G/A cg12935359 chr14:103987150 CKB 0.34 4.9 0.4 2.92e-6 Bone mineral density; TGCT cis rs360798 0.532 rs360800 chr2:62954326 C/T cg17519650 chr2:63277830 OTX1 -0.55 -4.49 -0.37 1.63e-5 Coronary artery disease; TGCT cis rs16867321 0.639 rs13028421 chr2:181444035 G/T cg23363182 chr2:181467187 NA 0.41 6.04 0.48 1.69e-8 Obesity; TGCT cis rs17102423 0.731 rs1957949 chr14:65542607 C/T cg11161011 chr14:65562177 MAX -0.43 -5.92 -0.47 2.97e-8 Obesity-related traits; TGCT cis rs3099143 1.000 rs901008 chr15:77097018 C/A cg21673338 chr15:77095150 SCAPER -0.51 -4.88 -0.4 3.17e-6 Recalcitrant atopic dermatitis; TGCT cis rs10927875 0.726 rs1763603 chr1:16339809 T/C cg21385522 chr1:16154831 NA 0.6 6.29 0.49 4.95e-9 Dilated cardiomyopathy; TGCT cis rs7572733 0.576 rs6734781 chr2:198759973 G/A cg00792783 chr2:198669748 PLCL1 0.57 5.21 0.42 7.75e-7 Dermatomyositis; TGCT cis rs7829975 0.846 rs7005216 chr8:8547110 C/G cg06636001 chr8:8085503 FLJ10661 -0.61 -5.05 -0.41 1.57e-6 Mood instability; TGCT cis rs7727544 0.735 rs272879 chr5:131670546 C/G cg24060327 chr5:131705240 SLC22A5 -0.56 -6.31 -0.49 4.43e-9 Blood metabolite levels; TGCT cis rs9326248 1.000 rs4938354 chr11:117051165 A/G cg26566898 chr11:117069891 TAGLN 0.33 4.67 0.39 7.55e-6 Blood protein levels; TGCT cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg27588902 chr6:42928151 GNMT -0.57 -7.05 -0.54 1.07e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs35883536 0.626 rs80052576 chr1:101039229 A/G cg10298815 chr1:101004474 GPR88 -0.24 -4.5 -0.37 1.57e-5 Monocyte count; TGCT cis rs7552404 0.920 rs1612097 chr1:76218875 C/T cg03433033 chr1:76189801 ACADM 0.76 9.01 0.63 3.15e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg22997113 chr7:27170241 HOXA4 -0.45 -4.45 -0.37 1.85e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs988712 0.662 rs11030100 chr11:27677586 G/T cg10635145 chr11:27742435 BDNF -0.39 -5.49 -0.44 2.2e-7 Obesity; TGCT cis rs875971 0.798 rs57739047 chr7:65972566 A/T cg11764359 chr7:65958608 NA 0.58 5.34 0.43 4.22e-7 Aortic root size; TGCT cis rs425277 1.000 rs262667 chr1:2082722 T/C cg24578937 chr1:2090814 PRKCZ 0.32 8.19 0.59 2.64e-13 Height; TGCT cis rs9926296 0.605 rs12599180 chr16:89839306 C/T cg04287289 chr16:89883240 FANCA -0.87 -10.91 -0.7 7.5599999999999994e-20 Vitiligo; TGCT cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg06238570 chr21:40685208 BRWD1 -0.63 -5.79 -0.46 5.47e-8 Cognitive function; TGCT cis rs6688613 1.000 rs6665341 chr1:166947018 A/G cg07049167 chr1:166818506 POGK 0.21 4.53 0.38 1.36e-5 Refractive astigmatism; TGCT cis rs4077515 0.743 rs3812571 chr9:139275294 G/C cg13741927 chr9:139327495 INPP5E -0.19 -4.59 -0.38 1.05e-5 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs11249608 0.636 rs6888567 chr5:178449074 C/T cg23951258 chr5:178450506 ZNF879 -0.46 -4.49 -0.37 1.58e-5 Pubertal anthropometrics; TGCT cis rs9948 0.655 rs62156213 chr2:97399100 T/C cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs7542091 1.000 rs7542091 chr1:210031948 G/C cg21951975 chr1:209979733 IRF6 0.54 5.56 0.45 1.56e-7 Monobrow; TGCT cis rs10791097 0.667 rs4937585 chr11:130741940 A/G cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6598955 0.585 rs11577098 chr1:26602525 C/T cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs9419702 0.639 rs9419624 chr10:133534822 G/A cg20568497 chr10:133558893 NA 0.44 4.87 0.4 3.4e-6 Survival in rectal cancer; TGCT cis rs9467773 0.804 rs2073526 chr6:26374658 C/T cg05738196 chr6:26577821 NA -0.6 -6.2 -0.49 7.53e-9 Intelligence (multi-trait analysis); TGCT cis rs2730260 0.537 rs73169238 chr7:158883818 G/A cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs1801251 1.000 rs11676216 chr2:233706368 C/T cg08000102 chr2:233561755 GIGYF2 -0.63 -6.46 -0.5 2.2e-9 Coronary artery disease; TGCT cis rs6089584 0.888 rs6061966 chr20:60607936 C/G cg13770153 chr20:60521292 NA -0.54 -7.04 -0.53 1.15e-10 Body mass index; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg12419862 chr22:24373484 LOC391322 0.89 7.86 0.58 1.55e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1005277 0.579 rs2505198 chr10:38393183 A/C cg25427524 chr10:38739819 LOC399744 -0.38 -7.77 -0.57 2.54e-12 Extrinsic epigenetic age acceleration; TGCT cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.68e-9 Blood metabolite levels; TGCT trans rs1814175 0.817 rs7109440 chr11:49966296 C/T cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs7412746 0.658 rs12068264 chr1:150727329 C/T cg09365446 chr1:150670422 GOLPH3L 0.33 4.78 0.39 4.8e-6 Melanoma; TGCT cis rs1451375 1.000 rs10247443 chr7:50620586 G/A cg18232548 chr7:50535776 DDC 0.43 6.65 0.51 8.19e-10 Malaria; TGCT cis rs709400 0.628 rs2273699 chr14:103923475 A/G cg26031613 chr14:104095156 KLC1 0.85 9.49 0.65 2.17e-16 Body mass index; TGCT cis rs28493229 0.708 rs4803352 chr19:41159193 C/T cg11601297 chr19:41224147 ITPKC;ADCK4 -0.55 -5.15 -0.42 9.8e-7 Kawasaki disease; TGCT cis rs10114408 0.959 rs7868037 chr9:96647901 A/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs3820068 0.608 rs12091644 chr1:16044945 G/A cg05660106 chr1:15850417 CASP9 0.73 6.78 0.52 4.41e-10 Systolic blood pressure; TGCT cis rs2115630 1.000 rs6496441 chr15:85363348 A/G cg09876464 chr15:85330779 ZNF592 0.19 4.46 0.37 1.78e-5 P wave terminal force; TGCT cis rs10089 0.953 rs2190797 chr5:127352875 C/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.73 6.75 0.52 5e-10 Ileal carcinoids; TGCT cis rs7089973 0.624 rs10885613 chr10:116589400 G/A cg03647239 chr10:116582469 FAM160B1 0.59 5.75 0.46 6.46e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg20203395 chr5:56204925 C5orf35 -0.78 -6.46 -0.5 2.17e-9 Initial pursuit acceleration; TGCT cis rs1005277 0.579 rs2474572 chr10:38385316 A/G cg25427524 chr10:38739819 LOC399744 -0.38 -7.92 -0.58 1.17e-12 Extrinsic epigenetic age acceleration; TGCT cis rs696279 0.967 rs697511 chr7:16700648 C/A cg08595592 chr7:16780162 NA 0.24 4.74 0.39 5.67e-6 Mean platelet volume; TGCT cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg09904177 chr6:26538194 HMGN4 0.67 6.32 0.49 4.25e-9 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.909 rs6060929 chr20:30345914 C/T cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs17384381 0.861 rs34561661 chr1:85777250 C/T cg16011679 chr1:85725395 C1orf52 0.86 6.19 0.49 8.17e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9549260 0.683 rs35594717 chr13:41240783 G/A cg21288729 chr13:41239152 FOXO1 0.7 4.94 0.41 2.51e-6 Red blood cell count; TGCT cis rs7095607 0.606 rs10998014 chr10:69959567 C/A cg18986048 chr10:69913749 MYPN 0.52 5.29 0.43 5.35e-7 Lung function (FVC); TGCT cis rs829883 0.664 rs1096148 chr12:98851005 A/G cg25150519 chr12:98850993 NA 0.64 7.54 0.56 8.56e-12 Colorectal adenoma (advanced); TGCT cis rs7582180 0.591 rs1030902 chr2:101007178 T/G cg14675211 chr2:100938903 LONRF2 0.49 4.7 0.39 6.74e-6 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.715 rs12777801 chr10:1036285 T/A cg18964960 chr10:1102726 WDR37 0.78 5.45 0.44 2.58e-7 Eosinophil percentage of granulocytes; TGCT cis rs1801251 1.000 rs3816334 chr2:233708806 A/G cg08000102 chr2:233561755 GIGYF2 -0.63 -6.46 -0.5 2.2e-9 Coronary artery disease; TGCT cis rs968451 1.000 rs971964 chr22:39702473 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.87 7.8 0.57 2.23e-12 Primary biliary cholangitis; TGCT cis rs514406 0.679 rs11206006 chr1:53218380 A/G cg22166914 chr1:53195759 ZYG11B -0.37 -5.99 -0.47 2.15e-8 Monocyte count; TGCT cis rs6570726 0.846 rs4896824 chr6:145927048 C/T cg23711669 chr6:146136114 FBXO30 0.83 8.64 0.61 2.4e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs61884328 0.852 rs60335739 chr11:47148728 C/T cg13308137 chr11:47528955 CUGBP1 0.38 4.47 0.37 1.76e-5 Total body bone mineral density (age over 60); TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg00786635 chr1:25594202 NA -0.51 -5.32 -0.43 4.67e-7 Erythrocyte sedimentation rate; TGCT cis rs7666738 0.753 rs6826709 chr4:98714553 C/G cg18180107 chr4:99064573 C4orf37 0.55 5.17 0.42 8.93e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 1.000 rs974495 chr3:49400482 T/C cg07636037 chr3:49044803 WDR6 0.66 5.33 0.43 4.45e-7 Menarche (age at onset); TGCT cis rs4295623 0.556 rs10903343 chr8:11695872 T/C cg02840367 chr8:11660030 FDFT1 -0.67 -5.67 -0.45 9.68e-8 Morning vs. evening chronotype; TGCT cis rs6500602 0.727 rs3761681 chr16:4566857 C/T cg08645402 chr16:4508243 NA 0.19 5.3 0.43 5.08e-7 Schizophrenia; TGCT cis rs13191362 1.000 rs13207239 chr6:163008772 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs33794 0.729 rs33783 chr3:45291959 G/T cg18645101 chr3:44551900 NA 0.5 4.48 0.37 1.7e-5 Lung function (forced expiratory volume in 1 second); TGCT cis rs6866344 0.697 rs6873150 chr5:178125704 G/A cg03877680 chr5:178157825 ZNF354A 0.73 5.73 0.46 7.07e-8 Neutrophil percentage of white cells; TGCT cis rs79349575 0.783 rs9747646 chr17:47016882 C/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs11673344 0.504 rs7259332 chr19:37634291 G/T cg08039142 chr19:36980659 ZNF566 0.51 4.69 0.39 6.97e-6 Obesity-related traits; TGCT cis rs765787 0.530 rs12440321 chr15:45529385 G/A cg24006582 chr15:45444508 DUOX1 0.24 5.3 0.43 5.17e-7 Uric acid levels; TGCT cis rs12900413 0.603 rs12905689 chr15:90301343 G/A cg24249390 chr15:90295951 MESP1 -0.3 -5.23 -0.42 7.05e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs3858526 0.642 rs55732658 chr11:5894602 A/C cg13902645 chr11:5959945 NA -0.41 -4.49 -0.37 1.6e-5 DNA methylation (variation); TGCT cis rs875971 0.660 rs3764903 chr7:66098482 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg03188948 chr7:1209495 NA 0.67 5.62 0.45 1.18e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6740322 0.748 rs1549723 chr2:43460514 C/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.02 -0.48 1.86e-8 Coronary artery disease; TGCT cis rs727505 0.721 rs11536526 chr7:124749441 G/A cg23710748 chr7:124431027 NA -0.26 -4.56 -0.38 1.2e-5 Lewy body disease; TGCT cis rs4372836 1.000 rs72782294 chr2:28953390 C/G cg09522027 chr2:28974177 PPP1CB 0.59 5.14 0.42 1.03e-6 Body mass index; TGCT cis rs1395 0.778 rs11693001 chr2:27412744 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.64 8.74 0.62 1.37e-14 Blood metabolite levels; TGCT trans rs2970818 0.831 rs7304949 chr12:4609625 A/G cg21748317 chr7:158073589 PTPRN2 0.45 7.16 0.54 6.14e-11 Phosphorus levels; TGCT cis rs3806843 0.576 rs246011 chr5:140336405 G/C cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs2832191 1.000 rs2832190 chr21:30488226 G/A cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs9911578 0.935 rs34523895 chr17:57034095 T/C cg05425664 chr17:57184151 TRIM37 -0.56 -5.42 -0.44 2.99e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg11644478 chr21:40555479 PSMG1 -1.03 -11.03 -0.7 3.93e-20 Cognitive function; TGCT cis rs4713118 0.866 rs2179094 chr6:27741825 T/C cg02458000 chr6:26745757 NA -0.57 -4.97 -0.41 2.18e-6 Parkinson's disease; TGCT cis rs9535307 0.769 rs9535306 chr13:50290817 A/G cg03651054 chr13:50194643 NA 0.37 4.49 0.37 1.61e-5 Obesity-related traits; TGCT cis rs12477438 0.798 rs17708218 chr2:99696284 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.74 -0.62 1.36e-14 Chronic sinus infection; TGCT cis rs644799 1.000 rs518919 chr11:95623313 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.73 7.25 0.55 3.87e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs854765 0.547 rs6502633 chr17:17941037 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.26 0.6 1.86e-13 Total body bone mineral density; TGCT cis rs67073037 0.955 rs12472068 chr2:29136685 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs17712049 0.908 rs62447151 chr7:48199772 C/G cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs7584330 0.554 rs729389 chr2:238425118 G/A cg08992911 chr2:238395768 MLPH 0.73 4.95 0.41 2.37e-6 Prostate cancer; TGCT cis rs7781977 0.920 rs62447179 chr7:50339609 G/A cg01139861 chr7:50343298 IKZF1 0.53 5.63 0.45 1.12e-7 IgG glycosylation; TGCT trans rs114540395 0.698 rs7098584 chr10:103209336 G/A cg10198749 chr1:39920707 MACF1 0.55 7.11 0.54 8.11e-11 Schizophrenia; TGCT cis rs881375 1.000 rs1609810 chr9:123642351 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.5 0.37 1.52e-5 Rheumatoid arthritis; TGCT cis rs16925187 1.000 rs7850439 chr9:7042390 A/C cg00667760 chr9:6757146 KDM4C -1.07 -5.09 -0.42 1.3e-6 Response to fenofibrate (adiponectin levels); TGCT cis rs801193 1.000 rs2659906 chr7:66165310 T/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs4253772 0.530 rs55653327 chr22:46682976 C/T cg24881330 chr22:46731750 TRMU 1.01 4.95 0.41 2.35e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs9926296 0.706 rs2159115 chr16:89831819 A/G cg26513180 chr16:89883248 FANCA 0.67 6.44 0.5 2.41e-9 Vitiligo; TGCT cis rs1691799 0.867 rs1168347 chr12:66757303 T/C cg16791601 chr12:66731901 HELB -0.28 -5.99 -0.47 2.14e-8 White blood cell count (basophil); TGCT cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs9303401 0.573 rs35104446 chr17:57180234 A/C cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs7584330 0.666 rs72620817 chr2:238353661 C/T cg14458575 chr2:238380390 NA 0.55 8.09 0.59 4.56e-13 Prostate cancer; TGCT cis rs7267979 0.932 rs6115214 chr20:25557426 C/T cg14121845 chr20:25566513 NINL -0.48 -5.24 -0.43 6.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11031096 0.678 rs4606468 chr11:4183643 G/T cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs17102423 0.594 rs1957948 chr14:65542629 A/G cg11161011 chr14:65562177 MAX 0.48 6.78 0.52 4.29e-10 Obesity-related traits; TGCT cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg00684032 chr4:1343700 KIAA1530 0.23 5.02 0.41 1.73e-6 Obesity-related traits; TGCT cis rs2463822 0.669 rs72919496 chr11:62052730 T/C cg06239285 chr11:62104954 ASRGL1 -0.91 -5.82 -0.46 4.7e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg18230493 chr5:56204884 C5orf35 -0.69 -6.07 -0.48 1.44e-8 Initial pursuit acceleration; TGCT cis rs6969780 1.000 rs929249 chr7:27167537 T/C cg04321618 chr7:27170880 HOXA4 0.51 4.48 0.37 1.67e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2255336 0.938 rs1382264 chr12:10543339 A/G cg16084090 chr12:10586130 KLRC2 -0.28 -4.67 -0.39 7.56e-6 Blood protein levels; TGCT cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg16414030 chr3:133502952 NA -0.5 -7.01 -0.53 1.32e-10 Iron status biomarkers; TGCT cis rs28386778 0.765 rs1974435 chr17:61994096 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.48 -4.65 -0.39 8.42e-6 Prudent dietary pattern; TGCT cis rs9467711 0.606 rs9379851 chr6:26354780 A/C cg16898833 chr6:26189333 HIST1H4D 1.03 5.35 0.43 4.02e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4499344 0.730 rs10410888 chr19:33103328 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.63 0.61 2.53e-14 Mean platelet volume; TGCT cis rs736408 0.812 rs9324 chr3:52825585 T/C cg07507251 chr3:52567010 NT5DC2 0.45 6.17 0.48 8.78e-9 Bipolar disorder; TGCT cis rs2153535 0.580 rs9328486 chr6:8528008 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs1629083 0.902 rs57495164 chr11:118095148 T/C cg16594165 chr11:118135105 MPZL2 -0.33 -4.7 -0.39 6.73e-6 Lung cancer; TGCT cis rs916888 0.738 rs199515 chr17:44856641 C/G cg16520312 chr17:43971471 MAPT;LOC100128977 0.56 4.81 0.4 4.28e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2742417 1.000 rs2742390 chr3:45756722 A/G cg04837898 chr3:45731254 SACM1L 0.56 5.97 0.47 2.3e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs947211 0.846 rs823155 chr1:205762946 T/C cg07167872 chr1:205819463 PM20D1 0.45 4.48 0.37 1.7e-5 Parkinson's disease; TGCT cis rs10832169 0.967 rs1528639 chr11:14070459 G/C cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg10263370 chr3:44754102 ZNF502 -0.47 -5.67 -0.45 9.48e-8 Depressive symptoms; TGCT cis rs12421382 0.659 rs1439518 chr11:109382921 T/G cg16359550 chr11:109292809 C11orf87 0.4 4.48 0.37 1.65e-5 Schizophrenia; TGCT cis rs4820539 1.000 rs4822358 chr22:23474795 A/G cg21100191 chr22:23484243 RTDR1 0.89 10.58 0.69 5.04e-19 Bone mineral density; TGCT cis rs7819412 0.635 rs4841501 chr8:11000976 T/C cg21775007 chr8:11205619 TDH -0.57 -5.41 -0.44 3.18e-7 Triglycerides; TGCT cis rs9818758 0.556 rs9835439 chr3:49220330 G/C cg07636037 chr3:49044803 WDR6 -1.03 -5.02 -0.41 1.77e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs7582180 0.629 rs12989897 chr2:100940998 A/G cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.571 rs1105114 chr11:93693511 C/T cg26875233 chr11:93583750 C11orf90 0.43 5.16 0.42 9.71e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs1814175 0.817 rs1319547 chr11:49916705 C/T cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs2188554 0.711 rs213947 chr7:117192608 A/G cg08576598 chr7:116962626 WNT2 -0.36 -4.56 -0.38 1.23e-5 Esophageal adenocarcinoma; TGCT cis rs7772486 0.875 rs2748482 chr6:146336532 T/C cg23711669 chr6:146136114 FBXO30 0.88 9.67 0.66 7.78e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1843834 0.898 rs4674936 chr2:225553731 C/T cg22455342 chr2:225449267 CUL3 0.75 7.37 0.55 2.15e-11 IgE levels in asthmatics (D.p. specific); TGCT trans rs9383153 0.625 rs1886349 chr6:16320320 G/A cg19402885 chr12:15475236 PTPRO 1.0 6.71 0.52 6.22e-10 Gambling; TGCT cis rs7017914 0.967 rs2639901 chr8:71917751 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.31 -0.43 4.8e-7 Bone mineral density; TGCT cis rs17376456 1.000 rs13174700 chr5:93554644 G/A cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 7.92e-6 Diabetic retinopathy; TGCT cis rs9682041 0.696 rs6798399 chr3:170086482 G/A cg11886554 chr3:170076028 SKIL 0.6 4.76 0.39 5.35e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7727544 0.606 rs200838 chr5:131710399 A/C cg14196790 chr5:131705035 SLC22A5 -0.37 -5.2 -0.42 8.01e-7 Blood metabolite levels; TGCT cis rs9611565 0.592 rs9611612 chr22:41961189 T/C cg17554472 chr22:41940697 POLR3H -0.47 -4.91 -0.4 2.79e-6 Vitiligo; TGCT cis rs250677 0.687 rs250673 chr5:148445798 C/T cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs10788264 0.621 rs9633733 chr10:124056546 A/G cg09507567 chr10:124027408 NA -0.37 -5.32 -0.43 4.71e-7 Total body bone mineral density; TGCT cis rs208515 0.556 rs12206707 chr6:66697182 A/G cg07460842 chr6:66804631 NA 0.88 9.36 0.64 4.39e-16 Exhaled nitric oxide levels; TGCT cis rs17376456 0.542 rs17083380 chr5:93170476 C/G cg21475434 chr5:93447410 FAM172A -0.59 -5.58 -0.45 1.44e-7 Diabetic retinopathy; TGCT cis rs3784262 0.669 rs6493981 chr15:58352923 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs66573146 0.808 rs73202120 chr4:7005588 A/G cg00086871 chr4:6988644 TBC1D14 0.96 4.85 0.4 3.57e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs2224391 0.628 rs9405261 chr6:5249702 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg27286337 chr10:134555280 INPP5A 0.37 4.54 0.38 1.3e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs4820539 1.000 rs2157710 chr22:23457486 C/T cg21100191 chr22:23484243 RTDR1 0.93 11.2 0.71 1.54e-20 Bone mineral density; TGCT cis rs9905704 0.647 rs7221274 chr17:57008128 A/G cg12560992 chr17:57184187 TRIM37 0.58 4.93 0.4 2.57e-6 Testicular germ cell tumor; TGCT cis rs8056742 0.730 rs78274149 chr16:85084293 G/A cg00229868 chr16:85520891 NA 0.36 4.83 0.4 3.96e-6 Amyotrophic lateral sclerosis; TGCT cis rs7819412 0.744 rs6601562 chr8:10962929 G/C cg27411982 chr8:10470053 RP1L1 -0.2 -4.44 -0.37 1.94e-5 Triglycerides; TGCT cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg06634786 chr22:41940651 POLR3H -0.87 -8.2 -0.59 2.56e-13 Vitiligo; TGCT cis rs4891159 0.527 rs689642 chr18:74119120 A/C cg24786174 chr18:74118243 ZNF516 0.71 15.66 0.82 3.6e-31 Longevity; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg11141652 chr22:24348549 GSTTP1 -0.34 -4.82 -0.4 4.17e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs508618 0.731 rs11805033 chr1:231546452 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.62 5.11 0.42 1.18e-6 Red blood cell count; TGCT cis rs4665809 1.000 rs4665820 chr2:26309150 T/C cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs919433 0.679 rs7564924 chr2:198513877 C/T cg00792783 chr2:198669748 PLCL1 0.55 4.97 0.41 2.15e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs11761231 1.000 rs11761231 chr7:131370039 A/G cg08326674 chr7:132266446 PLXNA4 0.23 4.59 0.38 1.09e-5 Rheumatoid arthritis; TGCT cis rs7412746 0.611 rs36008098 chr1:150856806 G/A cg04414720 chr1:150670196 GOLPH3L 0.4 4.82 0.4 4.06e-6 Melanoma; TGCT cis rs12497850 1.000 rs4858831 chr3:48735558 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.93 0.47 2.75e-8 Parkinson's disease; TGCT cis rs13217239 0.646 rs10456351 chr6:26986792 C/T cg05738196 chr6:26577821 NA 0.49 4.77 0.39 4.98e-6 Schizophrenia; TGCT cis rs1971762 0.563 rs3897117 chr12:54077407 T/G cg16917193 chr12:54089295 NA 1.37 17.65 0.85 1.25e-35 Height; TGCT cis rs5750830 0.594 rs6001587 chr22:39819008 T/C cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs4771122 0.728 rs1475221 chr13:28037566 C/T cg22138327 chr13:27999177 GTF3A -0.7 -5.65 -0.45 1.02e-7 Body mass index; TGCT cis rs2795502 1.000 rs2795503 chr10:43347224 T/A cg20628663 chr10:43360327 NA -0.45 -6.41 -0.5 2.71e-9 Blood protein levels; TGCT cis rs514406 0.505 rs269289 chr1:53167151 A/C cg25767906 chr1:53392781 SCP2 -0.47 -5.13 -0.42 1.09e-6 Monocyte count; TGCT cis rs986417 1.000 rs12147690 chr14:60924009 A/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs1729951 0.575 rs1654925 chr3:136690391 C/T cg21827317 chr3:136751795 NA -0.4 -5.61 -0.45 1.28e-7 Neuroticism; TGCT cis rs797680 0.856 rs7547244 chr1:93781768 A/G cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.791 rs1896156 chr4:99020882 C/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 1.000 rs8177262 chr3:133480652 A/G cg01448562 chr3:133502909 NA 0.3 6.0 0.47 2.04e-8 Iron status biomarkers; TGCT cis rs910316 1.000 rs175436 chr14:75608683 C/G cg08847533 chr14:75593920 NEK9 -0.95 -10.23 -0.68 3.53e-18 Height; TGCT cis rs2050392 0.517 rs302423 chr10:30772513 A/G cg18806716 chr10:30721971 MAP3K8 -0.5 -5.82 -0.46 4.68e-8 Inflammatory bowel disease; TGCT cis rs7267979 0.868 rs6138546 chr20:25216534 G/A cg16686733 chr20:25566563 NINL 0.59 6.04 0.48 1.64e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13191362 0.507 rs2155506 chr6:163035342 G/A cg21926612 chr6:163149169 PACRG;PARK2 -0.61 -5.84 -0.46 4.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs858239 0.601 rs1558313 chr7:23156079 G/A cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9419702 0.568 rs10782366 chr10:133557866 G/A cg23460707 chr10:133558971 NA 0.44 4.84 0.4 3.72e-6 Survival in rectal cancer; TGCT cis rs12681288 0.550 rs12674921 chr8:957969 A/C cg04851639 chr8:1020857 NA -0.27 -4.45 -0.37 1.85e-5 Schizophrenia; TGCT cis rs2242116 0.793 rs9855938 chr3:46957298 G/A cg02527881 chr3:46936655 PTH1R -0.29 -5.47 -0.44 2.36e-7 Birth weight; TGCT cis rs3796352 0.764 rs34872575 chr3:52986277 G/A cg07884673 chr3:53033167 SFMBT1 0.63 5.74 0.46 6.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9486715 0.758 rs9386528 chr6:96928514 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -6.14 -0.48 1.01e-8 Headache; TGCT cis rs796364 1.000 rs769949 chr2:200729558 A/G cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs10782582 0.609 rs2029682 chr1:76341619 T/C cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs4822044 0.617 rs13054514 chr22:42130383 A/G cg03806693 chr22:41940476 POLR3H 0.93 9.08 0.63 2.06e-15 Cannabis dependence symptom count; TGCT cis rs17253792 0.822 rs17253716 chr14:56153661 G/C cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs2404602 0.716 rs12907805 chr15:76690606 C/T cg26408565 chr15:76604113 ETFA -0.42 -5.44 -0.44 2.76e-7 Blood metabolite levels; TGCT cis rs936229 0.749 rs7497201 chr15:75190690 A/G cg10253484 chr15:75165896 SCAMP2 -0.77 -6.49 -0.5 1.85e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs7666738 0.830 rs6854594 chr4:99065312 A/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1153858 1.000 rs9788780 chr15:45685487 T/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs4319547 0.695 rs4758645 chr12:122946487 G/A cg23029597 chr12:123009494 RSRC2 -0.28 -4.52 -0.38 1.43e-5 Body mass index; TGCT cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg13770153 chr20:60521292 NA -0.59 -8.39 -0.6 9.32e-14 Obesity-related traits; TGCT cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7714584 0.793 rs11955174 chr5:150254391 T/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg06481639 chr22:41940642 POLR3H 0.63 5.66 0.45 1.02e-7 Vitiligo; TGCT cis rs17387100 0.551 rs2677782 chr4:16020824 C/G cg13480465 chr4:16795757 LDB2 -0.42 -5.33 -0.43 4.56e-7 Suicide attempts in depression or bipolar disorder; TGCT cis rs6688613 1.000 rs2296837 chr1:166958601 T/C cg07049167 chr1:166818506 POGK 0.21 4.5 0.37 1.57e-5 Refractive astigmatism; TGCT cis rs748404 0.631 rs6493084 chr15:43647627 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs13202913 0.748 rs2859823 chr6:151815864 G/A cg03627880 chr6:151815985 C6orf97 -0.62 -5.75 -0.46 6.43e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT trans rs1814175 0.935 rs1827017 chr11:49632592 C/G cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs35306767 0.714 rs67205460 chr10:1090366 C/T cg18964960 chr10:1102726 WDR37 0.68 4.77 0.39 5.02e-6 Eosinophil percentage of granulocytes; TGCT cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs2115630 0.645 rs4842978 chr15:85197253 T/C cg17173187 chr15:85201210 NMB -0.48 -5.75 -0.46 6.41e-8 P wave terminal force; TGCT cis rs7949030 0.626 rs7124057 chr11:62334096 A/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.42 0.65 3.17e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6754311 0.638 rs2322659 chr2:136555659 A/G cg07169764 chr2:136633963 MCM6 -0.68 -6.19 -0.49 7.9e-9 Mosquito bite size; TGCT cis rs10791097 0.694 rs4457753 chr11:130755575 A/G cg05962950 chr11:130786565 SNX19 0.91 11.78 0.73 5.8e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4273100 0.512 rs973650 chr17:19291785 A/G cg03910582 chr17:19030146 GRAPL -0.45 -6.22 -0.49 6.97e-9 Schizophrenia; TGCT trans rs74910095 0.786 rs7726154 chr5:62941736 T/C cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6598955 0.670 rs6663950 chr1:26560131 T/C cg04990556 chr1:26633338 UBXN11 -0.91 -11.87 -0.73 3.59e-22 Obesity-related traits; TGCT cis rs7552404 0.807 rs2066183 chr1:76153745 A/G cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9653442 0.545 rs12712067 chr2:100763900 A/C cg07810366 chr2:100720526 AFF3 0.36 5.45 0.44 2.59e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6815814 0.950 rs113465719 chr4:38808045 A/T cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs9309473 0.615 rs11680965 chr2:73725916 G/T cg07208825 chr2:73871855 ALMS1P 0.24 4.62 0.38 9.64e-6 Metabolite levels; TGCT cis rs7666738 0.800 rs2865987 chr4:99067852 A/C cg18180107 chr4:99064573 C4orf37 0.59 5.32 0.43 4.76e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11676348 0.818 rs4674256 chr2:218987893 A/T cg00012203 chr2:219082015 ARPC2 -0.52 -4.98 -0.41 2.08e-6 Ulcerative colitis; TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg07424592 chr7:64974309 NA 1.36 8.08 0.59 4.97e-13 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs6545883 0.759 rs777585 chr2:61412559 A/G cg15711740 chr2:61764176 XPO1 0.52 4.6 0.38 1.02e-5 Tuberculosis; TGCT cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1401999 1.000 rs2872249 chr3:183636273 T/A cg01324343 chr3:183735012 ABCC5 0.85 11.47 0.72 3.33e-21 Anterior chamber depth; TGCT cis rs1971762 0.583 rs1527068 chr12:54088688 A/G cg16917193 chr12:54089295 NA 1.34 17.42 0.84 4.03e-35 Height; TGCT cis rs7949030 0.725 rs12808829 chr11:62378660 G/A cg11742103 chr11:62369870 EML3;MTA2 0.63 9.19 0.64 1.12e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs208520 0.754 rs1100989 chr6:66880532 G/A cg07460842 chr6:66804631 NA -0.91 -9.43 -0.65 2.99e-16 Exhaled nitric oxide output; TGCT cis rs12711979 0.740 rs6715434 chr2:3820862 T/G cg17052675 chr2:3827356 NA -0.4 -7.82 -0.57 2.02e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7824557 0.569 rs2409718 chr8:11012977 C/T cg27411982 chr8:10470053 RP1L1 -0.21 -4.67 -0.39 7.77e-6 Retinal vascular caliber; TGCT cis rs1878931 0.501 rs28735976 chr16:3418419 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.12 0.54 7.59e-11 Body mass index (adult); TGCT cis rs3858526 1.000 rs3858526 chr11:5959757 A/C cg13902645 chr11:5959945 NA -0.43 -4.65 -0.39 8.43e-6 DNA methylation (variation); TGCT cis rs6121246 0.567 rs6058189 chr20:30192389 A/G cg18721089 chr20:30220636 NA -0.57 -6.22 -0.49 6.83e-9 Mean corpuscular hemoglobin; TGCT trans rs9467711 1.000 rs9467707 chr6:26327905 G/C cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs4372836 0.504 rs2045886 chr2:29010517 A/G cg09522027 chr2:28974177 PPP1CB -0.56 -5.68 -0.45 9.2e-8 Body mass index; TGCT trans rs877282 0.898 rs71489279 chr10:760510 T/C cg22713356 chr15:30763199 NA 1.17 9.15 0.63 1.44e-15 Uric acid levels; TGCT cis rs7904368 1.000 rs7904368 chr10:16858587 C/T cg23933602 chr10:16859644 RSU1 0.64 4.99 0.41 1.97e-6 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs367615 0.661 rs9326773 chr5:108833523 C/T cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs425277 0.606 rs2257182 chr1:2082566 C/T cg03732007 chr1:2071316 PRKCZ -0.28 -6.56 -0.51 1.31e-9 Height; TGCT cis rs739496 0.579 rs75080921 chr12:112298972 T/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs909674 0.524 rs5757670 chr22:39829736 G/A cg01416388 chr22:39784598 NA -0.7 -6.94 -0.53 1.9e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs13118159 1.000 rs13118159 chr4:1365127 A/G cg22683308 chr4:1340831 KIAA1530 -0.64 -5.93 -0.47 2.76e-8 Longevity; TGCT cis rs4654899 0.895 rs7515590 chr1:21216664 T/C cg01072550 chr1:21505969 NA 0.49 7.7 0.57 3.76e-12 Superior frontal gyrus grey matter volume; TGCT cis rs295140 0.502 rs3769456 chr2:201239002 C/T cg04283868 chr2:201171347 SPATS2L 0.52 4.98 0.41 2.06e-6 QT interval; TGCT cis rs11792861 0.926 rs7855282 chr9:111802614 T/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.47 4.46 0.37 1.79e-5 Menarche (age at onset); TGCT cis rs2836950 0.520 rs2836966 chr21:40637521 A/G cg06238570 chr21:40685208 BRWD1 -0.61 -6.19 -0.49 7.89e-9 Menarche (age at onset); TGCT cis rs9650657 0.707 rs11250076 chr8:10647823 A/G cg27411982 chr8:10470053 RP1L1 -0.24 -5.05 -0.41 1.54e-6 Neuroticism; TGCT cis rs2288884 1.000 rs79817140 chr19:52571657 C/T cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs1116547 0.684 rs2091803 chr5:112578543 C/T cg04138046 chr5:112608004 MCC -0.46 -4.65 -0.39 8.46e-6 Cerebral amyloid angiopathy; TGCT cis rs644799 0.544 rs1622515 chr11:95523433 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.56 5.76 0.46 6.32e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7655841 0.704 rs1757936 chr4:130011891 G/A cg26347359 chr4:129759716 PHF17 -0.45 -5.2 -0.42 7.86e-7 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs34245846 0.769 rs12058931 chr1:154825093 C/A cg06418219 chr1:154948305 SHC1;CKS1B 0.74 5.93 0.47 2.84e-8 Atrial fibrillation; TGCT cis rs6912958 0.712 rs2814712 chr6:88396322 A/C cg06598631 chr6:88300029 RARS2;ORC3L 0.49 4.72 0.39 6.37e-6 Monocyte percentage of white cells; TGCT cis rs3806843 0.705 rs35614340 chr5:140043618 C/G cg19875535 chr5:140030758 IK -0.36 -6.15 -0.48 9.57e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9942416 0.660 rs2307113 chr5:74998264 C/T cg02573091 chr5:74908125 NA 0.38 4.51 0.38 1.47e-5 Age-related disease endophenotypes; TGCT cis rs10871290 0.881 rs4099290 chr16:74468889 A/G cg01733217 chr16:74700730 RFWD3 -0.61 -5.8 -0.46 5.1e-8 Breast cancer; TGCT cis rs2120019 1.000 rs2415255 chr15:75332412 A/G cg09165964 chr15:75287851 SCAMP5 -1.14 -10.22 -0.68 3.76e-18 Blood trace element (Zn levels); TGCT cis rs9733 0.596 rs11582840 chr1:150688487 A/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs7582180 0.629 rs4851295 chr2:100945605 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs6988636 1.000 rs13259806 chr8:124190103 A/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs2239785 0.727 rs136156 chr22:36656442 C/A cg15716373 chr22:36655542 APOL1 -0.43 -5.37 -0.43 3.8e-7 Glomerulosclerosis; TGCT cis rs6089584 0.507 rs6061989 chr20:60627893 C/T cg13770153 chr20:60521292 NA -0.43 -5.15 -0.42 9.9e-7 Body mass index; TGCT cis rs2153535 0.580 rs6597325 chr6:8461053 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs763121 0.853 rs2064088 chr22:39053382 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs3741404 0.620 rs2236648 chr11:63964657 C/T cg00022866 chr11:64108440 CCDC88B 0.24 4.51 0.38 1.47e-5 Platelet count; TGCT cis rs3820068 0.705 rs4646083 chr1:15825564 G/A cg05660106 chr1:15850417 CASP9 1.18 13.63 0.77 2.04e-26 Systolic blood pressure; TGCT cis rs631288 0.793 rs10900331 chr1:146733128 C/G cg25205988 chr1:146714368 CHD1L 1.25 6.03 0.48 1.7e-8 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.39 -0.44 3.35e-7 Initial pursuit acceleration; TGCT cis rs10880689 1 rs10880689 chr12:37930102 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.82 0.57 1.94e-12 Resting heart rate; TGCT cis rs12681288 0.676 rs35389636 chr8:1010613 G/T cg04851639 chr8:1020857 NA -0.28 -4.62 -0.38 9.42e-6 Schizophrenia; TGCT cis rs9473924 0.505 rs9473938 chr6:50874050 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs981844 0.816 rs62325148 chr4:154727993 A/G cg14289246 chr4:154710475 SFRP2 1.03 9.04 0.63 2.61e-15 Response to statins (LDL cholesterol change); TGCT cis rs7267979 0.932 rs6138600 chr20:25521346 A/T cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7655441 0.964 rs6824433 chr4:80857151 C/A cg02241357 chr4:80885279 ANTXR2 -0.23 -4.46 -0.37 1.81e-5 Neutrophil percentage of white cells; TGCT cis rs1857353 1.000 rs17584397 chr1:75894453 A/G cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs7666738 0.791 rs7660866 chr4:98961335 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1729951 0.575 rs16844325 chr3:136678161 C/G cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg11494091 chr17:61959527 GH2 0.42 6.96 0.53 1.76e-10 Height; TGCT trans rs1814175 0.645 rs7103554 chr11:50027612 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs1629083 0.902 rs10892226 chr11:118096618 G/A cg16594165 chr11:118135105 MPZL2 -0.33 -4.62 -0.38 9.3e-6 Lung cancer; TGCT cis rs617791 0.669 rs4994056 chr11:65750997 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.65 6.4 0.5 2.96e-9 Breast cancer; TGCT cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg14983838 chr19:29218262 NA 0.83 6.76 0.52 4.75e-10 Methadone dose in opioid dependence; TGCT cis rs11935103 0.569 rs7656763 chr4:187294858 C/G cg16785698 chr4:186456103 PDLIM3 -0.46 -4.68 -0.39 7.45e-6 Response to citalopram treatment; TGCT cis rs4727027 0.754 rs11764892 chr7:148858916 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.55 4.65 0.39 8.37e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3733585 0.699 rs7437120 chr4:9967683 T/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.72 -0.52 5.82e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6582630 0.537 rs12823925 chr12:38409323 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.51 0.56 1e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1395 0.778 rs34618115 chr2:27418289 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.66 9.16 0.64 1.39e-15 Blood metabolite levels; TGCT cis rs9858542 0.953 rs11711485 chr3:49491983 G/T cg03060546 chr3:49711283 APEH -0.62 -5.46 -0.44 2.52e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7937840 0.501 rs4963459 chr11:61877137 G/A cg05871569 chr11:61891931 INCENP 0.77 8.36 0.6 1.11e-13 Breast cancer; TGCT cis rs7100689 0.646 rs11202725 chr10:82136276 A/G cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs875971 0.964 rs778708 chr7:65856319 T/C cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs3020736 0.500 rs2839708 chr22:42500745 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs694739 0.894 rs887314 chr11:64053157 T/G cg02228329 chr11:64053129 BAD;GPR137 0.75 7.5 0.56 1.08e-11 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs17076896 0.881 rs61956064 chr13:19928890 G/T cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT trans rs2760061 0.819 rs1745417 chr1:228204279 C/T cg16006296 chr10:38738647 LOC399744 -0.31 -7.21 -0.54 4.89e-11 Diastolic blood pressure; TGCT cis rs950169 0.580 rs11633762 chr15:85187152 T/C cg11189052 chr15:85197271 WDR73 0.75 6.21 0.49 7.32e-9 Schizophrenia; TGCT cis rs4713675 0.553 rs943465 chr6:33731663 G/A cg18005901 chr6:33739558 LEMD2 -0.51 -5.65 -0.45 1.05e-7 Plateletcrit; TGCT cis rs1580019 0.563 rs896137 chr7:32579345 G/T cg06627557 chr7:32535165 LSM5;AVL9 1.2 15.12 0.81 6.42e-30 Cognitive ability; TGCT cis rs1215050 0.791 rs984940 chr4:98811756 T/A cg17366294 chr4:99064904 C4orf37 0.54 5.79 0.46 5.38e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6484504 0.532 rs12222329 chr11:31274340 T/C cg26647111 chr11:31128758 NA -0.35 -4.86 -0.4 3.44e-6 Red blood cell count; TGCT trans rs916888 0.610 rs199536 chr17:44820425 T/C cg01341218 chr17:43662625 NA -0.83 -7.37 -0.55 2.14e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2535633 0.631 rs2245424 chr3:53003021 G/C cg05573699 chr3:52720067 GNL3;PBRM1 0.53 5.12 0.42 1.15e-6 Body mass index; TGCT cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg10047753 chr17:41438598 NA 0.96 9.1 0.63 1.9e-15 Menopause (age at onset); TGCT cis rs9807989 0.811 rs67088699 chr2:102968751 C/T cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs17376456 0.825 rs10038828 chr5:93124056 C/T cg25358565 chr5:93447407 FAM172A 0.9 7.65 0.57 4.86e-12 Diabetic retinopathy; TGCT cis rs7621025 0.500 rs9845460 chr3:136587117 A/G cg15507776 chr3:136538369 TMEM22 0.67 6.26 0.49 5.69e-9 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs4566357 0.615 rs12328878 chr2:227918962 G/A cg11843606 chr2:227700838 RHBDD1 -0.55 -5.26 -0.43 6.22e-7 Coronary artery disease; TGCT cis rs6089584 0.888 rs2181590 chr20:60622843 T/C cg06108461 chr20:60628389 TAF4 -0.69 -10.64 -0.69 3.59e-19 Body mass index; TGCT cis rs9653442 0.527 rs10185059 chr2:100790172 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.25 -0.43 6.45e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs56309584 0.596 rs8075078 chr17:8186096 C/T cg08322244 chr17:8066669 VAMP2 -0.57 -5.31 -0.43 4.95e-7 Initial pursuit acceleration; TGCT cis rs4911253 0.527 rs853859 chr20:31402269 A/G cg13636640 chr20:31349939 DNMT3B 0.8 8.49 0.61 5.39e-14 Lymphocyte counts; TGCT cis rs6089584 0.853 rs1740367 chr20:60574834 C/T cg13770153 chr20:60521292 NA -0.47 -6.01 -0.48 1.9e-8 Body mass index; TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs1153858 0.945 rs2467854 chr15:45701597 A/G cg26924012 chr15:45694286 SPATA5L1 0.99 12.38 0.74 2.11e-23 Homoarginine levels; TGCT cis rs597539 0.652 rs514833 chr11:68657734 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.13 0.59 3.82e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs1908814 0.516 rs10112958 chr8:11793140 A/G cg15556689 chr8:8085844 FLJ10661 0.77 7.37 0.55 2.13e-11 Neuroticism; TGCT trans rs1814175 0.645 rs7952104 chr11:49964180 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs896854 0.812 rs4582532 chr8:95969257 G/A cg16049864 chr8:95962084 TP53INP1 -0.75 -10.28 -0.68 2.7e-18 Type 2 diabetes; TGCT cis rs6500602 0.727 rs4786515 chr16:4578133 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.95 0.47 2.54e-8 Schizophrenia; TGCT cis rs2014572 0.933 rs8109882 chr19:57755618 C/G cg24459738 chr19:57751996 ZNF805 -0.54 -5.4 -0.44 3.21e-7 Hyperactive-impulsive symptoms; TGCT cis rs4665809 1.000 rs4665809 chr2:26251361 C/T cg22920501 chr2:26401640 FAM59B 0.72 6.38 0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs8180040 0.615 rs13062681 chr3:47021124 A/G cg27129171 chr3:47204927 SETD2 0.73 9.42 0.65 3.15e-16 Colorectal cancer; TGCT cis rs548181 0.545 rs1054997 chr11:125618813 G/A cg03464685 chr11:125439445 EI24 -1.31 -7.78 -0.57 2.47e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs13191362 0.872 rs35443919 chr6:163055804 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.86 0.52 2.88e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs941873 0.868 rs7898 chr10:81114959 C/T cg09469691 chr10:81107165 PPIF 0.55 5.42 0.44 2.93e-7 Height; TGCT cis rs3087591 0.960 rs11870097 chr17:29448097 C/T cg24425628 chr17:29625626 OMG;NF1 0.47 7.3 0.55 3.03e-11 Hip circumference; TGCT cis rs7666738 0.830 rs1426669 chr4:98945534 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs28493229 0.521 rs2604878 chr19:41191971 G/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.48 4.62 0.38 9.44e-6 Kawasaki disease; TGCT cis rs12908161 1.000 rs56864281 chr15:85357649 C/A cg17173187 chr15:85201210 NMB 0.57 6.35 0.5 3.63e-9 Schizophrenia; TGCT cis rs9733 0.596 rs1336898 chr1:150665050 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs3741151 1.000 rs57893472 chr11:73042826 C/T cg17517138 chr11:73019481 ARHGEF17 0.97 4.96 0.41 2.28e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs3733585 0.699 rs4515163 chr4:9959603 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9443645 0.901 rs6937465 chr6:79570345 G/T cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs4383453 0.539 rs56712020 chr3:123099368 G/A cg04890266 chr3:123102914 ADCY5 -0.5 -8.34 -0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs7178572 0.568 rs7166927 chr15:77673459 A/G cg22256960 chr15:77711686 NA 0.88 9.16 0.64 1.32e-15 Type 2 diabetes; TGCT cis rs6665290 0.669 rs3768424 chr1:227177444 A/G cg10327440 chr1:227177885 CDC42BPA -0.91 -15.21 -0.81 4.04e-30 Myeloid white cell count; TGCT cis rs597539 0.690 rs497149 chr11:68626639 A/T cg21862992 chr11:68658383 NA 0.47 6.45 0.5 2.29e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11785400 0.793 rs4587307 chr8:143738529 G/A cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs765787 0.530 rs4270107 chr15:45535350 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs12220238 0.841 rs10824146 chr10:76076779 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.87 6.44 0.5 2.37e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs57590327 0.679 rs62265397 chr3:81543883 A/T cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs1215050 0.740 rs185468 chr4:98756242 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6722750 0.783 rs11125991 chr2:64387765 A/G cg22352474 chr2:64371530 PELI1 0.67 6.33 0.49 4e-9 Neuroticism; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg11003573 chr3:44754125 ZNF502 -0.47 -5.44 -0.44 2.75e-7 Depressive symptoms; TGCT cis rs9443645 0.901 rs2050662 chr6:79753073 G/C cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs3749615 chr5:601485 C/T cg20362242 chr5:692897 TPPP 0.51 4.54 0.38 1.33e-5 Obesity-related traits; TGCT cis rs1153858 1.000 rs1719247 chr15:45620985 C/T cg26924012 chr15:45694286 SPATA5L1 0.97 11.56 0.72 2.03e-21 Homoarginine levels; TGCT cis rs9811920 0.535 rs792833 chr3:99475268 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.39 -4.6 -0.38 1.04e-5 Axial length; TGCT cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.39 -0.5 3.02e-9 Alzheimer's disease; TGCT cis rs1153858 1.000 rs67831559 chr15:45649307 G/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs2180341 1.000 rs6904520 chr6:127629802 T/C cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs2075371 0.673 rs35290398 chr7:134011773 C/T cg11752832 chr7:134001865 SLC35B4 0.62 5.18 0.42 8.84e-7 Mean platelet volume; TGCT cis rs2549003 1.000 rs2548999 chr5:131831058 G/T cg00255919 chr5:131827918 IRF1 -0.2 -4.71 -0.39 6.59e-6 Asthma (sex interaction); TGCT cis rs12791968 1.000 rs11038237 chr11:45001880 C/T cg11846598 chr11:44996168 LOC221122 -0.35 -6.65 -0.51 8.24e-10 Inhibitory control; TGCT cis rs950776 0.518 rs56007453 chr15:78826239 T/C cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs1838472 0.607 rs11929003 chr3:123979321 A/G cg19008133 chr3:123124015 ADCY5 -0.19 -4.84 -0.4 3.74e-6 Schizophrenia; TGCT cis rs9640161 0.789 rs1464753 chr7:150021350 G/C cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 8.94e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs1865760 1.000 rs3830057 chr6:25918510 G/T cg16482183 chr6:26056742 HIST1H1C 0.51 4.55 0.38 1.25e-5 Height; TGCT cis rs3796352 1.000 rs11720191 chr3:53013839 T/C cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs951366 0.903 rs708723 chr1:205739266 C/T cg07157834 chr1:205819609 PM20D1 0.34 5.06 0.41 1.46e-6 Menarche (age at onset); TGCT cis rs7818688 0.697 rs60003497 chr8:95983423 A/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs6725041 0.792 rs1546719 chr2:213088582 G/C cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs858239 0.539 rs28624974 chr7:23188936 T/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2028414 0.512 rs752265 chr14:105361934 T/C cg16576083 chr14:105354267 KIAA0284 0.3 4.72 0.39 6.29e-6 IgG glycosylation; TGCT cis rs2033711 0.936 rs882609 chr19:58991479 G/A cg04608855 chr19:58913158 NA 0.51 4.68 0.39 7.5e-6 Uric acid clearance; TGCT cis rs4711350 0.953 rs1547668 chr6:33775446 A/G cg00334056 chr6:33755658 LEMD2 -0.3 -4.93 -0.41 2.54e-6 Schizophrenia; TGCT cis rs2439831 0.850 rs28707214 chr15:44131623 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT cis rs6582630 0.555 rs10880611 chr12:38509316 C/G cg13010199 chr12:38710504 ALG10B 0.6 4.88 0.4 3.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2840044 1.000 rs225262 chr17:33959697 A/G cg05299278 chr17:33885742 SLFN14 0.22 4.98 0.41 2.07e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs8017423 0.967 rs6575117 chr14:90715412 G/A cg04374321 chr14:90722782 PSMC1 0.74 7.74 0.57 2.98e-12 Mortality in heart failure; TGCT cis rs2074977 0.530 rs10401784 chr19:3445721 A/C cg08380311 chr19:3435252 NFIC 0.72 6.74 0.52 5.35e-10 Height; TGCT cis rs78366141 0.649 rs78114325 chr4:89682189 T/C cg01026744 chr4:89619053 NAP1L5;HERC3 1.15 5.23 0.43 6.86e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs732765 0.819 rs2058920 chr14:75311329 C/T cg06637938 chr14:75390232 RPS6KL1 0.6 5.2 0.42 7.87e-7 Non-small cell lung cancer; TGCT cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs7786808 0.530 rs7780796 chr7:158183330 C/T cg01191920 chr7:158217561 PTPRN2 0.35 4.96 0.41 2.26e-6 Obesity-related traits; TGCT cis rs4727027 0.901 rs1534198 chr7:148772323 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.99 0.41 2.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1483890 0.723 rs34184121 chr3:69411426 A/T cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs3796352 1.000 rs34979715 chr3:53048960 G/A cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4901869 0.902 rs2162491 chr14:59296247 C/T cg02291164 chr14:59296302 NA 0.27 5.19 0.42 8.43e-7 Panic disorder; TGCT cis rs7918232 1.000 rs7918232 chr10:27369162 A/G cg14442939 chr10:27389572 ANKRD26 0.74 5.47 0.44 2.35e-7 Breast cancer; TGCT cis rs4819852 1.000 rs1034566 chr22:19984277 C/T cg07821417 chr22:19972146 ARVCF 0.2 5.08 0.41 1.36e-6 Pulse pressure; TGCT cis rs2073300 1.000 rs17830565 chr20:23444805 G/A cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg13695892 chr22:41940480 POLR3H -0.85 -8.05 -0.59 5.63e-13 Vitiligo; TGCT cis rs9341808 0.935 rs942381 chr6:80880150 T/G cg08355045 chr6:80787529 NA 0.27 4.69 0.39 6.96e-6 Sitting height ratio; TGCT cis rs7590720 1.000 rs6435930 chr2:216885852 A/G cg12620499 chr2:216877984 MREG 0.85 9.27 0.64 7.33e-16 Alcohol dependence; TGCT cis rs763121 0.853 rs2267393 chr22:39101619 G/C cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6460942 0.908 rs6978367 chr7:12232347 A/G cg06484146 chr7:12443880 VWDE -0.53 -4.6 -0.38 1.03e-5 Coronary artery disease; TGCT cis rs60843830 1.000 rs60484953 chr2:221560 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.73 6.57 0.51 1.28e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2153535 0.580 rs9406158 chr6:8464152 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT trans rs7824557 0.545 rs2736303 chr8:11236850 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs61990749 0.597 rs1978416 chr14:78227901 C/T cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs6598955 0.670 rs7520517 chr1:26556385 A/C cg04990556 chr1:26633338 UBXN11 -0.91 -11.87 -0.73 3.59e-22 Obesity-related traits; TGCT cis rs2842992 0.915 rs2758350 chr6:160118056 A/G cg11366901 chr6:160182831 ACAT2 0.94 6.18 0.49 8.48e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs6430585 0.527 rs2304366 chr2:136467119 C/T cg07169764 chr2:136633963 MCM6 1.01 9.32 0.64 5.68e-16 Corneal structure; TGCT cis rs68170813 0.559 rs76843318 chr7:106863173 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs6121246 0.821 rs115585940 chr20:30317902 T/C cg13852791 chr20:30311386 BCL2L1 0.66 4.55 0.38 1.25e-5 Mean corpuscular hemoglobin; TGCT cis rs1475911 1.000 rs2839466 chr21:43512324 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 -0.57 -7.85 -0.58 1.67e-12 IgG glycosylation; TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.09 13.28 0.77 1.38e-25 Height; TGCT cis rs17376456 0.877 rs13185660 chr5:93336500 G/A cg21475434 chr5:93447410 FAM172A 0.63 4.77 0.39 5.14e-6 Diabetic retinopathy; TGCT cis rs9911578 1.000 rs368186 chr17:56736659 A/G cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs4566357 0.964 rs6436648 chr2:227923004 C/A cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs13256369 0.901 rs13251887 chr8:8568678 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.57 0.38 1.18e-5 Obesity-related traits; TGCT cis rs3806843 0.547 rs246033 chr5:140332115 A/C cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs2777491 0.957 rs7163788 chr15:41704789 A/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.9 -0.7 8.27e-20 Ulcerative colitis; TGCT cis rs6074578 0.649 rs1935387 chr20:137127 A/G cg16931068 chr20:139680 DEFB127 -0.27 -4.88 -0.4 3.26e-6 Hirschsprung disease; TGCT cis rs6430585 0.583 rs2322813 chr2:136582809 A/G cg07169764 chr2:136633963 MCM6 1.22 11.84 0.73 4.08e-22 Corneal structure; TGCT cis rs7647973 0.922 rs7620024 chr3:49451691 G/A cg07636037 chr3:49044803 WDR6 -0.69 -5.67 -0.45 9.43e-8 Menarche (age at onset); TGCT cis rs35160687 0.901 rs12478653 chr2:86535394 A/C cg03171300 chr2:86307199 POLR1A -0.28 -4.81 -0.4 4.33e-6 Night sleep phenotypes; TGCT cis rs1008375 1.000 rs10805358 chr4:17652450 A/C cg10189774 chr4:17578691 LAP3 0.57 5.24 0.43 6.8e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4499344 0.696 rs398990 chr19:33104244 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs1401999 1.000 rs13317532 chr3:183641669 G/C cg01324343 chr3:183735012 ABCC5 0.85 11.45 0.72 3.69e-21 Anterior chamber depth; TGCT trans rs1814175 0.645 rs11040703 chr11:50024961 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs2013441 1.000 rs2703789 chr17:20162923 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs11671005 0.693 rs11666928 chr19:58914231 A/G cg13877915 chr19:58951672 ZNF132 0.66 4.9 0.4 2.94e-6 Mean platelet volume; TGCT cis rs36051895 0.632 rs10121316 chr9:5147539 C/T cg02405213 chr9:5042618 JAK2 0.73 10.1 0.67 7.06e-18 Pediatric autoimmune diseases; TGCT cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg16145915 chr7:1198662 ZFAND2A -0.46 -5.47 -0.44 2.33e-7 Longevity;Endometriosis; TGCT cis rs3796352 0.881 rs35384050 chr3:53008769 G/T cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9926296 0.744 rs164749 chr16:89708224 A/C cg01097406 chr16:89675127 NA 0.33 6.27 0.49 5.37e-9 Vitiligo; TGCT cis rs3796352 0.881 rs34238610 chr3:53026480 A/T cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10501293 0.746 rs7952577 chr11:43017703 G/A cg03447554 chr11:43094025 NA 0.43 6.14 0.48 1.03e-8 Cognitive performance; TGCT cis rs858239 0.600 rs4409314 chr7:23127952 T/C cg05602783 chr7:23145260 KLHL7 -0.7 -6.08 -0.48 1.37e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9308731 0.644 rs4627572 chr2:111873378 T/C cg04202892 chr2:111875749 ACOXL 0.55 6.29 0.49 4.97e-9 Chronic lymphocytic leukemia; TGCT cis rs12908161 0.959 rs34784022 chr15:85231906 T/C cg17173187 chr15:85201210 NMB 0.59 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs4727027 0.870 rs62507512 chr7:148799338 C/T cg23583168 chr7:148888333 NA -0.72 -9.11 -0.63 1.8e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs67311347 0.955 rs11719205 chr3:40417258 G/A cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs933688 0.941 rs6452954 chr5:90735692 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.07 10.69 0.69 2.68e-19 Smoking behavior; TGCT cis rs6460942 0.915 rs75158182 chr7:12456059 C/T cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT trans rs77457752 0.523 rs9696661 chr9:13901539 T/C cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.04e-10 Breast cancer; TGCT cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7681440 0.669 rs6814481 chr4:90805660 C/T cg20003494 chr4:90757398 SNCA -0.54 -4.76 -0.39 5.34e-6 Dementia with Lewy bodies; TGCT cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg04389838 chr3:44770851 ZNF501 0.37 4.83 0.4 4.02e-6 Depressive symptoms; TGCT cis rs7586879 0.593 rs10200566 chr2:25130462 G/T cg01884057 chr2:25150051 NA -0.33 -6.28 -0.49 5.26e-9 Body mass index; TGCT cis rs1113500 0.547 rs12076264 chr1:108557108 G/A cg22161131 chr1:109420278 GPSM2 -0.6 -5.83 -0.46 4.49e-8 Growth-regulated protein alpha levels; TGCT trans rs2688608 0.592 rs7908825 chr10:75554541 C/G cg13918328 chr10:52500089 ASAH2B -0.68 -6.78 -0.52 4.3e-10 Inflammatory bowel disease; TGCT cis rs739401 0.611 rs2071104 chr11:3036933 G/T cg05729581 chr11:3078854 CARS -0.54 -5.13 -0.42 1.07e-6 Longevity; TGCT cis rs2832191 0.646 rs2832214 chr21:30517127 C/T cg24692254 chr21:30365293 RNF160 -0.61 -5.31 -0.43 4.91e-7 Dental caries; TGCT cis rs6582630 0.537 rs7299661 chr12:38527713 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.84 0.58 1.81e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.830 rs60007031 chr4:98824753 G/C cg05340658 chr4:99064831 C4orf37 0.51 6.03 0.48 1.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 1.000 rs6083809 chr20:25329309 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6815814 0.851 rs4129009 chr4:38774889 T/C cg02016764 chr4:38805732 TLR1 -0.35 -5.55 -0.45 1.69e-7 Breast cancer; TGCT cis rs854572 0.600 rs854570 chr7:94952692 C/A cg01874867 chr7:94954059 PON1 0.33 4.87 0.4 3.37e-6 Paraoxonase activity; TGCT cis rs626457 0.883 rs682479 chr1:57375718 C/A cg14377849 chr1:56539619 NA -0.35 -4.43 -0.37 2.01e-5 Blood protein levels; TGCT cis rs1878931 0.517 rs17685105 chr16:3413749 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.82 -8.95 -0.63 4.33e-15 Body mass index (adult); TGCT cis rs61990749 0.597 rs6574402 chr14:78267950 C/A cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg17554472 chr22:41940697 POLR3H -0.5 -5.36 -0.43 3.95e-7 Vitiligo; TGCT cis rs3796352 1.000 rs34943350 chr3:53012888 C/T cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2836974 0.545 rs3167757 chr21:40714478 C/T cg11890956 chr21:40555474 PSMG1 0.75 7.46 0.56 1.29e-11 Cognitive function; TGCT cis rs10501293 0.625 rs7944433 chr11:42999452 A/T cg03447554 chr11:43094025 NA -0.42 -6.09 -0.48 1.31e-8 Cognitive performance; TGCT cis rs4253772 0.591 rs11704586 chr22:46685274 T/C cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs11719291 0.833 rs13074318 chr3:48816725 C/T cg07636037 chr3:49044803 WDR6 -1.0 -4.9 -0.4 2.93e-6 Cognitive function; TGCT cis rs3617 0.539 rs12629687 chr3:52950659 T/C cg11645453 chr3:52864694 ITIH4 -0.26 -5.01 -0.41 1.81e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1862618 0.671 rs906631 chr5:56245803 C/G cg12311346 chr5:56204834 C5orf35 0.57 6.09 0.48 1.28e-8 Initial pursuit acceleration; TGCT cis rs8017423 0.845 rs114583024 chr14:90727628 T/C cg04374321 chr14:90722782 PSMC1 0.76 7.63 0.57 5.3e-12 Mortality in heart failure; TGCT cis rs6496667 0.632 rs6496658 chr15:90884105 A/G cg22089800 chr15:90895588 ZNF774 0.62 5.3 0.43 5.2e-7 Rheumatoid arthritis; TGCT cis rs9467711 0.606 rs66823108 chr6:26377939 G/A cg10795676 chr6:26370623 BTN3A2 -0.47 -4.77 -0.39 5.18e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4711336 0.935 rs754404 chr6:33664730 T/C cg14003231 chr6:33640908 ITPR3 0.28 4.58 0.38 1.13e-5 Height; TGCT cis rs4478858 0.735 rs7523509 chr1:31788329 A/G cg07478791 chr1:31886160 SERINC2 -0.47 -4.51 -0.38 1.47e-5 Alcohol dependence; TGCT trans rs28735056 0.967 rs56328473 chr18:77636101 C/T cg05926928 chr17:57297772 GDPD1 -0.71 -7.64 -0.57 5e-12 Schizophrenia; TGCT cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.46e-9 Electroencephalogram traits; TGCT cis rs916888 0.821 rs199504 chr17:44861003 C/T cg15921436 chr17:44337874 NA -0.51 -6.92 -0.53 2.11e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12477438 0.501 rs6751927 chr2:99740175 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.0 0.63 3.26e-15 Chronic sinus infection; TGCT cis rs909674 0.818 rs8136980 chr22:39844574 G/A cg05872129 chr22:39784769 NA -0.98 -10.17 -0.67 4.81e-18 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs8033133 0.647 rs1124767 chr15:25326173 T/C cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.25 -4.95 -0.41 2.37e-6 Blood osmolality (transformed sodium); TGCT cis rs6500602 0.702 rs56895104 chr16:4548132 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.65 0.45 1.02e-7 Schizophrenia; TGCT cis rs806215 0.901 rs989100 chr7:127220918 T/C cg25922125 chr7:127225783 GCC1 -0.6 -6.2 -0.49 7.6e-9 Type 2 diabetes; TGCT cis rs4478858 0.662 rs6425735 chr1:31783945 T/C cg07478791 chr1:31886160 SERINC2 -0.48 -4.61 -0.38 1e-5 Alcohol dependence; TGCT cis rs2066819 1.000 rs2629447 chr12:56700809 G/A cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT cis rs7809950 1.000 rs12668402 chr7:107173020 G/A cg23024343 chr7:107201750 COG5 -0.35 -5.55 -0.45 1.67e-7 Coronary artery disease; TGCT cis rs35306767 0.715 rs17221456 chr10:1037234 T/C cg26597838 chr10:835615 NA 0.63 7.0 0.53 1.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs2455799 0.545 rs9815740 chr3:15867632 A/G cg12172478 chr3:16357591 RFTN1 -0.31 -4.74 -0.39 5.64e-6 Mean platelet volume; TGCT cis rs4900538 0.821 rs8016191 chr14:102825340 G/A cg18135206 chr14:102964638 TECPR2 -0.2 -4.86 -0.4 3.45e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs8038465 0.622 rs56712926 chr15:73886849 G/T cg15420318 chr15:73925796 NPTN 0.67 7.07 0.54 9.91e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6570726 0.791 rs12205752 chr6:145896118 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2485376 0.813 rs56238324 chr10:104149814 C/G cg26089160 chr10:104170217 PSD 0.52 5.09 0.42 1.3e-6 QT interval; TGCT cis rs6570726 0.935 rs454614 chr6:145832633 C/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg17554472 chr22:41940697 POLR3H -0.47 -4.89 -0.4 3.06e-6 Vitiligo; TGCT trans rs7726839 0.718 rs6887972 chr5:597274 C/G cg25482853 chr8:67687455 SGK3 0.97 7.64 0.57 5.1e-12 Obesity-related traits; TGCT cis rs9911578 0.967 rs4932693 chr17:57110327 T/C cg05425664 chr17:57184151 TRIM37 0.66 6.48 0.5 1.92e-9 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.825 rs55724660 chr5:93276636 A/G cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs6570726 0.935 rs415590 chr6:145851244 T/C cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.652 rs513359 chr11:68669496 A/T cg06112835 chr11:68658793 MRPL21 -0.47 -8.29 -0.6 1.58e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs561341 0.714 rs473535 chr17:30312365 A/G cg20587970 chr11:113659929 NA -1.03 -12.33 -0.74 2.79e-23 Hip circumference adjusted for BMI; TGCT cis rs10504229 1.000 rs76944716 chr8:58191643 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -5.35 -0.43 4.14e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs28516388 chr4:98987449 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs858239 0.676 rs3807459 chr7:23389751 T/C cg05602783 chr7:23145260 KLHL7 -0.6 -5.07 -0.41 1.43e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg20007245 chr22:24372913 LOC391322 -0.69 -6.87 -0.52 2.81e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9906944 0.707 rs8068981 chr17:47122525 T/C cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs477895 0.838 rs2001003 chr11:64018687 C/A cg23719950 chr11:63933701 MACROD1 -0.69 -5.74 -0.46 6.94e-8 Mean platelet volume; TGCT cis rs1801251 1.000 rs13003675 chr2:233584109 C/T cg25237894 chr2:233734115 C2orf82 0.32 5.81 0.46 5.01e-8 Coronary artery disease; TGCT cis rs10492096 0.947 rs10849483 chr12:6635374 G/A cg00459232 chr12:6309025 CD9 0.36 4.47 0.37 1.77e-5 Hip geometry; TGCT cis rs2933343 0.649 rs789216 chr3:128594503 A/C cg11901034 chr3:128598214 ACAD9 -0.63 -5.98 -0.47 2.23e-8 IgG glycosylation; TGCT cis rs2204008 0.805 rs3863360 chr12:37966432 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.89 0.4 3.05e-6 Bladder cancer; TGCT cis rs3770081 1.000 rs1561328 chr2:86272758 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.18 -4.81 -0.4 4.33e-6 Facial emotion recognition (sad faces); TGCT cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7829975 0.742 rs1533058 chr8:8685190 A/G cg15556689 chr8:8085844 FLJ10661 0.65 5.94 0.47 2.72e-8 Mood instability; TGCT cis rs1153858 0.887 rs7164139 chr15:45670851 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs7659604 0.676 rs6534323 chr4:122695888 G/A cg06713675 chr4:122721982 EXOSC9 -0.6 -8.14 -0.59 3.6e-13 Type 2 diabetes; TGCT cis rs9443645 0.901 rs9352666 chr6:79572184 C/G cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.41 5.66 0.45 1.01e-7 Lymphocyte counts; TGCT cis rs586688 1.000 rs1736448 chr1:201644091 C/G cg05779441 chr1:201574716 NA 0.29 4.69 0.39 7.05e-6 Obesity-related traits; TGCT cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg24531977 chr5:56204891 C5orf35 0.97 9.1 0.63 1.86e-15 Initial pursuit acceleration; TGCT cis rs1577917 0.958 rs11752180 chr6:86573165 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.47 -0.44 2.33e-7 Response to antipsychotic treatment; TGCT cis rs231513 0.954 rs231500 chr17:41973374 T/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs72615157 0.634 rs79986079 chr7:99802044 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.61 4.9 0.4 2.91e-6 Lung function (FEV1/FVC); TGCT cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg07507251 chr3:52567010 NT5DC2 0.49 6.7 0.52 6.38e-10 Bipolar disorder; TGCT cis rs8180040 0.966 rs807932 chr3:47354241 C/T cg27129171 chr3:47204927 SETD2 0.7 8.88 0.62 6.43e-15 Colorectal cancer; TGCT cis rs986417 0.540 rs10144415 chr14:61112667 G/C cg27398547 chr14:60952738 C14orf39 1.55 10.36 0.68 1.66e-18 Gut microbiota (bacterial taxa); TGCT cis rs6543140 0.964 rs1523205 chr2:103070176 G/T cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs7617773 0.780 rs13082158 chr3:48372470 T/C cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs10032931 1.000 rs10032931 chr4:96458433 T/C cg17031751 chr4:96469067 UNC5C -0.42 -5.12 -0.42 1.14e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs16854884 0.657 rs16854819 chr3:143736126 C/T cg06585982 chr3:143692056 C3orf58 -0.56 -4.53 -0.38 1.37e-5 Economic and political preferences (feminism/equality); TGCT cis rs1008375 1.000 rs7688682 chr4:17693794 A/G cg18681998 chr4:17616180 MED28 -0.76 -7.12 -0.54 7.85e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4819052 0.851 rs2838844 chr21:46670733 A/C cg06618935 chr21:46677482 NA -0.38 -5.69 -0.45 8.75e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7412746 0.611 rs752376 chr1:150941381 C/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.5 0.37 1.52e-5 Melanoma; TGCT cis rs1163251 0.729 rs686362 chr1:120221011 T/C cg19096424 chr1:120255104 PHGDH 0.6 6.12 0.48 1.16e-8 Blood metabolite levels; TGCT cis rs9389248 0.690 rs2064101 chr6:135250530 G/A cg22676075 chr6:135203613 NA -0.51 -5.11 -0.42 1.17e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs3125734 0.633 rs7088891 chr10:64034019 G/T cg09941381 chr10:64027924 RTKN2 -0.37 -5.65 -0.45 1.04e-7 Rheumatoid arthritis; TGCT cis rs4499344 0.556 rs259225 chr19:33135458 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.26 0.6 1.84e-13 Mean platelet volume; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg19723775 chr5:179050963 HNRNPH1 0.52 5.33 0.43 4.51e-7 Lung cancer; TGCT cis rs986417 1.000 rs1956875 chr14:60846212 T/C cg27398547 chr14:60952738 C14orf39 -1.45 -10.38 -0.68 1.52e-18 Gut microbiota (bacterial taxa); TGCT cis rs2806561 0.734 rs1952527 chr1:23400969 T/C cg12483005 chr1:23474871 LUZP1 0.41 5.19 0.42 8.21e-7 Height; TGCT cis rs612683 0.621 rs508020 chr1:100955532 T/C cg06223162 chr1:101003688 GPR88 -0.35 -6.31 -0.49 4.4e-9 Breast cancer; TGCT cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs4654899 0.865 rs6426674 chr1:21483906 C/T cg01072550 chr1:21505969 NA -0.48 -7.14 -0.54 7.03e-11 Superior frontal gyrus grey matter volume; TGCT cis rs4819052 0.851 rs1056101 chr21:46678702 C/G cg06618935 chr21:46677482 NA -0.35 -5.28 -0.43 5.6e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3820068 0.581 rs16851841 chr1:15922713 A/G cg05660106 chr1:15850417 CASP9 0.83 8.29 0.6 1.58e-13 Systolic blood pressure; TGCT cis rs478304 0.651 rs11600918 chr11:65511965 A/G cg17480646 chr11:65405466 SIPA1 -0.56 -6.95 -0.53 1.84e-10 Acne (severe); TGCT cis rs11690935 0.788 rs6715929 chr2:172877507 A/G cg13550731 chr2:172543902 DYNC1I2 -0.81 -7.3 -0.55 3.05e-11 Schizophrenia; TGCT cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg11301795 chr4:187892539 NA -0.33 -5.11 -0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7219021 0.705 rs28635466 chr17:46983820 G/A cg26022315 chr17:47021804 SNF8 -0.53 -4.73 -0.39 5.96e-6 Schizophrenia or bipolar disorder; TGCT cis rs2293052 0.697 rs549040 chr12:117754348 A/G cg02962597 chr12:117799749 NOS1 0.27 4.65 0.39 8.28e-6 Schizophrenia; TGCT cis rs4595586 0.546 rs2056159 chr12:39270417 C/G cg26384229 chr12:38710491 ALG10B 0.66 5.38 0.43 3.64e-7 Morning vs. evening chronotype; TGCT cis rs10464366 0.517 rs13231075 chr7:39174806 G/T cg15212455 chr7:39170539 POU6F2 0.3 6.73 0.52 5.66e-10 IgG glycosylation; TGCT cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs4555082 0.834 rs2975217 chr14:105710238 A/C cg01266790 chr14:105781312 PACS2 0.54 4.44 0.37 1.95e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs790123 1.000 rs810976 chr3:122381683 T/C cg22896480 chr3:122379438 NA 0.2 5.27 0.43 5.82e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg12386194 chr3:101231763 SENP7 -0.58 -5.55 -0.45 1.64e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.817 rs7947286 chr11:49874657 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs1008375 0.966 rs10939735 chr4:17578891 A/G cg10189774 chr4:17578691 LAP3 0.61 5.28 0.43 5.6e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9527 0.590 rs7897663 chr10:104905604 T/C cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.09e-7 Arsenic metabolism; TGCT cis rs1903068 0.853 rs10012589 chr4:56002689 A/T cg16572876 chr4:56024045 NA 0.42 4.79 0.39 4.75e-6 Endometriosis; TGCT cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg20637647 chr7:64974828 NA 0.87 5.31 0.43 4.99e-7 Diabetic kidney disease; TGCT cis rs6463523 0.864 rs73047957 chr7:759373 A/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.87 11.91 0.73 2.85e-22 Subjective well-being; TGCT cis rs57994353 0.897 rs67220311 chr9:139376668 T/C cg13741927 chr9:139327495 INPP5E -0.23 -5.16 -0.42 9.54e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT trans rs28735056 0.903 rs56185453 chr18:77638297 A/G cg05926928 chr17:57297772 GDPD1 -0.83 -9.62 -0.65 1.05e-16 Schizophrenia; TGCT cis rs1532993 0.518 rs1508470 chr4:98575319 C/T cg05340658 chr4:99064831 C4orf37 0.41 5.0 0.41 1.92e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs35306767 0.953 rs11253517 chr10:970524 A/G cg26597838 chr10:835615 NA -0.61 -8.36 -0.6 1.08e-13 Eosinophil percentage of granulocytes; TGCT cis rs62103177 0.608 rs613847 chr18:77845644 A/G cg07235805 chr18:78004237 PARD6G -0.51 -4.98 -0.41 2.11e-6 Opioid sensitivity; TGCT cis rs597539 0.652 rs557625 chr11:68634722 G/A cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.35e-29 Prudent dietary pattern; TGCT cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs1552244 0.515 rs111560858 chr3:10166845 G/A cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs4478037 1.000 rs59229836 chr3:33162622 T/C cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs10833905 0.680 rs10833892 chr11:23027429 A/G cg06387204 chr11:22647648 FANCF -0.55 -5.07 -0.41 1.44e-6 Sudden cardiac arrest; TGCT cis rs2070488 0.965 rs6805386 chr3:38557921 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT cis rs910187 0.641 rs3818010 chr20:45816562 A/G cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs7178572 0.568 rs10152181 chr15:77678346 A/G cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT trans rs57221529 0.766 rs12522303 chr5:555564 A/C cg11887960 chr12:57824829 NA 1.15 9.35 0.64 4.71e-16 Lung disease severity in cystic fibrosis; TGCT cis rs6121246 0.567 rs7361893 chr20:30200751 C/T cg18721089 chr20:30220636 NA -0.57 -6.19 -0.49 7.9e-9 Mean corpuscular hemoglobin; TGCT cis rs9814567 0.806 rs2888670 chr3:134326684 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.77 -7.21 -0.54 4.87e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6988636 1.000 rs62521826 chr8:124186668 C/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs62380364 0.870 rs11749060 chr5:88152574 A/C cg22951263 chr5:87985283 NA 0.47 4.54 0.38 1.31e-5 Intelligence (multi-trait analysis); TGCT cis rs6831352 0.589 rs1133483 chr4:100023923 G/C cg13256891 chr4:100009986 ADH5 0.45 4.68 0.39 7.47e-6 Alcohol dependence; TGCT cis rs9296661 0.522 rs1326575 chr6:51667498 C/A cg20180370 chr6:50691003 TFAP2D -0.49 -4.65 -0.39 8.46e-6 Weight loss (gastric bypass surgery); TGCT cis rs11190604 1.000 rs2489037 chr10:102319918 A/G cg23241863 chr10:102295624 HIF1AN -0.67 -4.9 -0.4 2.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7017914 0.934 rs56043721 chr8:71630427 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs12421382 0.543 rs11213094 chr11:109357926 G/A cg27471124 chr11:109292789 C11orf87 0.53 6.26 0.49 5.73e-9 Schizophrenia; TGCT cis rs3924048 0.559 rs6541039 chr1:12626261 T/C cg00291366 chr1:12616550 NA 0.31 4.88 0.4 3.17e-6 Optic cup area; TGCT cis rs7178424 0.653 rs3886246 chr15:62140034 G/A cg00456672 chr15:62358751 C2CD4A -0.31 -4.67 -0.39 7.7e-6 Height; TGCT cis rs78707713 0.560 rs2394563 chr10:71238618 G/A cg12610070 chr10:71211762 TSPAN15 -0.62 -7.31 -0.55 2.83e-11 Venous thromboembolism; TGCT cis rs2594714 1.000 rs12162265 chr19:13955161 G/A cg18576835 chr19:13944261 NA -0.46 -5.06 -0.41 1.47e-6 Breast cancer; TGCT cis rs4808199 0.901 rs11669516 chr19:19532682 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 4.99 0.41 1.98e-6 Nonalcoholic fatty liver disease; TGCT cis rs6121246 0.529 rs6060118 chr20:30171209 T/C cg21427119 chr20:30132790 HM13 -0.39 -5.81 -0.46 4.97e-8 Mean corpuscular hemoglobin; TGCT cis rs1218582 0.710 rs9794000 chr1:154878876 T/A cg06221963 chr1:154839813 KCNN3 -0.73 -11.82 -0.73 4.65e-22 Prostate cancer; TGCT cis rs12477438 0.666 rs10179910 chr2:99658503 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.68 -6.44 -0.5 2.32e-9 Chronic sinus infection; TGCT cis rs7666738 0.830 rs13134819 chr4:98919885 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.23 0.43 6.88e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2370759 0.945 rs74625866 chr10:32597618 A/T cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg24675658 chr1:53192096 ZYG11B -0.69 -8.17 -0.59 3.05e-13 Monocyte count; TGCT cis rs1008375 0.872 rs6831115 chr4:17640463 A/G cg16339924 chr4:17578868 LAP3 0.64 5.47 0.44 2.42e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs8072100 0.805 rs67919208 chr17:45771873 T/C cg08085267 chr17:45401833 C17orf57 -0.4 -4.64 -0.38 8.84e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT trans rs17471911 0.708 rs11189943 chr10:100785546 T/C cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg26354017 chr1:205819088 PM20D1 0.55 6.43 0.5 2.46e-9 Menarche (age at onset); TGCT cis rs360798 0.512 rs6739804 chr2:63269604 T/C cg17519650 chr2:63277830 OTX1 0.62 5.71 0.46 7.87e-8 Coronary artery disease; TGCT cis rs514406 0.861 rs7524476 chr1:53240212 C/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs13326165 0.760 rs55965068 chr3:52354432 A/G cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs9296092 0.517 rs56043172 chr6:33522363 T/G cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg20999797 chr1:1681921 NA 0.18 4.51 0.38 1.5e-5 Body mass index; TGCT cis rs7264396 0.635 rs6060660 chr20:34476649 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs3935685 0.874 rs4477663 chr15:78007254 A/G cg03457338 chr15:78040120 NA 0.22 5.82 0.46 4.77e-8 Intelligence (multi-trait analysis); TGCT cis rs12887734 0.546 rs4906376 chr14:104272165 A/C cg26031613 chr14:104095156 KLC1 -0.69 -5.83 -0.46 4.49e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs8013055 0.846 rs12717698 chr14:105979015 G/A cg19700328 chr14:106028568 NA -0.56 -5.88 -0.47 3.48e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs2115630 1.000 rs8037423 chr15:85355494 C/T cg12501888 chr15:85177176 SCAND2 -0.48 -4.49 -0.37 1.62e-5 P wave terminal force; TGCT cis rs9914544 1.000 rs7223231 chr17:18811846 C/T cg26378065 chr17:18585709 ZNF286B 0.52 4.65 0.38 8.54e-6 Educational attainment (years of education); TGCT cis rs17270561 1.000 rs79867288 chr6:25828416 A/G cg17691542 chr6:26056736 HIST1H1C 0.78 4.78 0.39 4.87e-6 Iron status biomarkers; TGCT trans rs9329221 0.741 rs9650622 chr8:9804292 G/T cg06636001 chr8:8085503 FLJ10661 -0.77 -6.92 -0.53 2.12e-10 Neuroticism; TGCT cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg03517284 chr6:25882590 NA -0.52 -5.27 -0.43 5.77e-7 Blood metabolite levels; TGCT cis rs17376456 0.809 rs13177800 chr5:93307350 T/C cg21475434 chr5:93447410 FAM172A 0.66 4.81 0.4 4.26e-6 Diabetic retinopathy; TGCT cis rs7647973 0.925 rs6769821 chr3:49244657 G/A cg07636037 chr3:49044803 WDR6 0.64 5.13 0.42 1.09e-6 Menarche (age at onset); TGCT cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg15659132 chr6:26577336 NA 0.84 10.91 0.7 7.83e-20 Intelligence (multi-trait analysis); TGCT cis rs6978712 1.000 rs56060721 chr7:127148448 A/G cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs10425738 0.536 rs10426903 chr19:41417719 T/C cg19493303 chr19:41414353 NA 0.44 5.51 0.44 1.94e-7 nicotine metabolite ratio in current smokers;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); TGCT cis rs67311347 0.544 rs1454492 chr3:40352884 C/T cg13683864 chr3:40499215 RPL14 -0.8 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs13242816 1.000 rs17138750 chr7:116134170 A/G cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT cis rs2456568 0.778 rs7940973 chr11:93682045 C/G cg16099599 chr11:93583650 C11orf90 0.39 4.8 0.4 4.39e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs72781680 1.000 rs17762782 chr2:24126493 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs9902453 0.740 rs2254414 chr17:28061130 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.39 -0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs3784262 0.692 rs1441819 chr15:58243204 A/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.19 -0.49 8.09e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1577917 0.876 rs12212808 chr6:86533972 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs1865760 0.865 rs9467648 chr6:25957933 T/A cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg24675658 chr1:53192096 ZYG11B -0.84 -10.28 -0.68 2.58e-18 Monocyte count; TGCT cis rs854765 0.647 rs4426402 chr17:17977926 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.68 -6.99 -0.53 1.51e-10 Total body bone mineral density; TGCT cis rs2688608 0.592 rs7076585 chr10:75503692 T/C cg23231163 chr10:75533350 FUT11 -0.28 -4.73 -0.39 5.98e-6 Inflammatory bowel disease; TGCT cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg11644478 chr21:40555479 PSMG1 1.03 11.1 0.71 2.61e-20 Cognitive function; TGCT cis rs28595532 0.920 rs115076001 chr4:119764346 T/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs270601 0.739 rs3900945 chr5:131592870 T/C cg24060327 chr5:131705240 SLC22A5 -0.66 -6.96 -0.53 1.78e-10 Acylcarnitine levels; TGCT cis rs6977955 0.838 rs917115 chr7:28172586 T/C cg23620719 chr7:28220237 JAZF1 0.58 4.66 0.39 8.03e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs3816788 0.792 rs729180 chr8:21817245 C/T cg17168535 chr8:21777572 XPO7 0.81 8.33 0.6 1.25e-13 Lung cancer in ever smokers; TGCT cis rs425277 1.000 rs809912 chr1:2078385 C/T cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs4975709 0.589 rs4975746 chr5:1861069 G/A cg12288994 chr5:1860383 NA 0.24 4.72 0.39 6.2e-6 Cardiovascular disease risk factors; TGCT cis rs1552244 0.882 rs68153882 chr3:10013110 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs896854 0.517 rs1011796 chr8:95951273 A/G cg09323728 chr8:95962352 TP53INP1 0.44 5.06 0.41 1.47e-6 Type 2 diabetes; TGCT cis rs478304 0.627 rs11604568 chr11:65511336 G/A cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.03e-10 Acne (severe); TGCT cis rs36051895 0.659 rs3780367 chr9:5068755 T/G cg02405213 chr9:5042618 JAK2 -0.74 -9.81 -0.66 3.67e-17 Pediatric autoimmune diseases; TGCT cis rs12210905 0.688 rs114188783 chr6:27449604 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT trans rs7726839 0.574 rs11134148 chr5:637107 C/T cg25482853 chr8:67687455 SGK3 1.22 10.53 0.69 6.33e-19 Obesity-related traits; TGCT cis rs3020736 0.500 rs9620026 chr22:42498578 C/T cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg09177884 chr7:1199841 ZFAND2A -0.52 -5.04 -0.41 1.63e-6 Longevity;Endometriosis; TGCT cis rs2797160 1.000 rs1832980 chr6:125997444 T/G cg05901451 chr6:126070800 HEY2 -0.74 -6.49 -0.5 1.84e-9 Endometrial cancer; TGCT cis rs910316 0.967 rs175498 chr14:75536369 G/A cg23033748 chr14:75592666 NEK9 -0.28 -4.7 -0.39 6.7e-6 Height; TGCT cis rs2224391 0.704 rs9504371 chr6:5261608 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.8 -6.12 -0.48 1.13e-8 Height; TGCT cis rs2760061 0.659 rs708107 chr1:228189495 C/T cg02753203 chr1:228287806 NA 0.31 5.79 0.46 5.54e-8 Diastolic blood pressure; TGCT cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg23283495 chr1:209979779 IRF6 0.66 5.36 0.43 3.86e-7 Cleft lip with or without cleft palate; TGCT cis rs9393777 0.513 rs9379907 chr6:26654318 C/T cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.649 rs6002480 chr22:42176917 A/T cg03806693 chr22:41940476 POLR3H -0.89 -8.61 -0.61 2.72e-14 Vitiligo; TGCT cis rs55665837 0.524 rs2882128 chr11:14414634 A/C cg19336497 chr11:14380999 RRAS2 -0.3 -4.64 -0.38 8.58e-6 Vitamin D levels; TGCT cis rs11690935 0.610 rs59844139 chr2:172731983 C/A cg13550731 chr2:172543902 DYNC1I2 0.57 4.62 0.38 9.5e-6 Schizophrenia; TGCT cis rs35883536 0.647 rs10875316 chr1:101044150 G/A cg10298815 chr1:101004474 GPR88 -0.24 -4.44 -0.37 1.95e-5 Monocyte count; TGCT cis rs7772486 0.875 rs854148 chr6:146310979 G/C cg05347473 chr6:146136440 FBXO30 0.54 5.0 0.41 1.91e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs1005277 0.579 rs932538 chr10:38381314 T/C cg27523141 chr10:43048294 ZNF37B 0.71 8.32 0.6 1.35e-13 Extrinsic epigenetic age acceleration; TGCT cis rs11734570 0.581 rs73808504 chr4:38600593 T/C cg18361445 chr4:38666374 KLF3;FLJ13197 0.69 5.66 0.45 9.9e-8 Inflammatory bowel disease;Crohn's disease; TGCT cis rs10193935 0.901 rs62142596 chr2:42529339 C/T cg27598129 chr2:42591480 NA -0.38 -5.17 -0.42 9.27e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg27588902 chr6:42928151 GNMT -0.49 -5.95 -0.47 2.53e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg08280861 chr8:58055591 NA 0.49 5.38 0.43 3.64e-7 Developmental language disorder (linguistic errors); TGCT cis rs597539 0.652 rs482172 chr11:68668437 C/A cg04772025 chr11:68637568 NA 0.6 6.78 0.52 4.26e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11031096 0.782 rs2284450 chr11:4149214 A/T cg18678763 chr11:4115507 RRM1 -0.51 -6.59 -0.51 1.14e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs12497850 0.931 rs9835307 chr3:48857805 T/C cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs7666738 0.830 rs28878289 chr4:98855181 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg16414030 chr3:133502952 NA -0.52 -7.29 -0.55 3.17e-11 Iron status biomarkers; TGCT cis rs1801251 1.000 rs283477 chr2:233649427 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.41 0.5 2.78e-9 Coronary artery disease; TGCT cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs45509595 0.749 rs401763 chr6:27782528 T/C cg10876282 chr6:28092338 ZSCAN16 0.78 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs7666738 0.830 rs17550610 chr4:99008273 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.775 rs12369238 chr12:38176051 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.68 0.57 4.21e-12 Bladder cancer; TGCT cis rs4455778 0.580 rs7777309 chr7:49085524 C/T cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs7617480 0.648 rs9848268 chr3:48762271 C/T cg07636037 chr3:49044803 WDR6 0.74 5.88 0.47 3.51e-8 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs11711311 0.747 rs9882193 chr3:113349451 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.72 6.11 0.48 1.17e-8 IgG glycosylation; TGCT cis rs4654899 0.897 rs6670897 chr1:21066376 T/C cg01072550 chr1:21505969 NA -0.49 -7.85 -0.58 1.67e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2797160 1.000 rs2747724 chr6:126004935 G/A cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs68170813 0.641 rs1978085 chr7:107095216 T/C cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs28374715 0.627 rs28516832 chr15:41367036 G/A cg18705301 chr15:41695430 NDUFAF1 -0.75 -9.77 -0.66 4.5e-17 Ulcerative colitis; TGCT cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4788570 0.584 rs9934301 chr16:71756845 C/G cg06353428 chr16:71660113 MARVELD3 1.49 12.95 0.76 8.56e-25 Intelligence (multi-trait analysis); TGCT cis rs9560113 1.000 rs9560110 chr13:112181233 C/T cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs9650657 0.770 rs9969626 chr8:10670801 A/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.66 -0.39 7.97e-6 Neuroticism; TGCT cis rs17376456 0.825 rs6877030 chr5:93201841 C/A cg21475434 chr5:93447410 FAM172A 0.69 4.81 0.4 4.36e-6 Diabetic retinopathy; TGCT cis rs950169 0.580 rs2271431 chr15:85189464 A/C cg12863693 chr15:85201151 NMB 0.44 5.2 0.42 7.97e-7 Schizophrenia; TGCT cis rs68170813 0.652 rs76742243 chr7:107144202 G/A cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs2153535 0.553 rs2984099 chr6:8637274 C/T cg23788917 chr6:8435910 SLC35B3 -0.88 -6.83 -0.52 3.43e-10 Motion sickness; TGCT cis rs9910055 0.529 rs575798 chr17:42181796 A/C cg19774624 chr17:42201019 HDAC5 0.65 5.98 0.47 2.23e-8 Total body bone mineral density; TGCT cis rs6570726 0.791 rs392612 chr6:145881586 C/G cg05347473 chr6:146136440 FBXO30 -0.54 -5.15 -0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.55 -5.12 -0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs9811920 0.609 rs793462 chr3:99616461 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.82 -0.52 3.63e-10 Axial length; TGCT cis rs7829975 0.514 rs2976926 chr8:8261624 T/C cg06636001 chr8:8085503 FLJ10661 0.7 6.18 0.49 8.28e-9 Mood instability; TGCT cis rs2354432 0.607 rs2297752 chr1:146765454 C/G cg25205988 chr1:146714368 CHD1L -1.18 -7.03 -0.53 1.24e-10 Mitochondrial DNA levels; TGCT cis rs9325144 0.555 rs4882284 chr12:38710459 C/T cg26384229 chr12:38710491 ALG10B -0.68 -6.28 -0.49 5.18e-9 Morning vs. evening chronotype; TGCT cis rs7226408 0.802 rs11665058 chr18:34469552 C/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2820315 1.000 rs903678 chr1:201809918 G/A cg12730843 chr1:201915899 LMOD1 -0.27 -4.82 -0.4 4.09e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs7666738 0.830 rs1869897 chr4:98730997 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs57221529 0.766 rs4957053 chr5:575927 T/C cg09021430 chr5:549028 NA -0.37 -5.16 -0.42 9.7e-7 Lung disease severity in cystic fibrosis; TGCT cis rs7296418 0.663 rs28450974 chr12:123861420 G/A cg00376283 chr12:123451042 ABCB9 0.63 5.42 0.44 3.02e-7 Platelet count; TGCT cis rs12497850 1.000 rs1352420 chr3:48757291 A/G cg07636037 chr3:49044803 WDR6 0.93 9.94 0.67 1.8e-17 Parkinson's disease; TGCT cis rs17152411 0.947 rs61873270 chr10:126595923 C/A cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs9910055 0.747 rs2905981 chr17:42238625 C/T cg19774624 chr17:42201019 HDAC5 -0.83 -8.49 -0.61 5.19e-14 Total body bone mineral density; TGCT cis rs2249625 0.564 rs2463734 chr6:72882558 C/T cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT trans rs1496653 0.602 rs13076527 chr3:23385877 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs9653442 0.564 rs10185510 chr2:100790581 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.25 -0.43 6.45e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6938 0.618 rs11857695 chr15:75165751 G/T cg09165964 chr15:75287851 SCAMP5 0.53 5.08 0.42 1.33e-6 Breast cancer; TGCT cis rs7017914 0.967 rs34508469 chr8:71628463 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs4819052 0.851 rs28501512 chr21:46676702 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7727544 0.606 rs200838 chr5:131710399 A/C cg24060327 chr5:131705240 SLC22A5 0.51 5.44 0.44 2.73e-7 Blood metabolite levels; TGCT cis rs780096 0.506 rs1647265 chr2:27692261 A/G cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT trans rs941408 1.000 rs1624295 chr19:2792034 G/A cg19676328 chr12:49525230 TUBA1B -0.76 -7.72 -0.57 3.34e-12 Total cholesterol levels; TGCT cis rs2114646 0.697 rs1863694 chr2:170633728 A/G cg01268571 chr2:170624998 NA 0.46 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs7666738 0.677 rs13120306 chr4:99036099 A/T cg05340658 chr4:99064831 C4orf37 0.51 5.69 0.45 8.74e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs208520 0.690 rs10455194 chr6:66743356 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs554111 0.613 rs1567128 chr1:21404653 G/A cg01072550 chr1:21505969 NA 0.35 5.34 0.43 4.23e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs12220238 1.000 rs12355771 chr10:75894404 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs8141529 0.764 rs5752809 chr22:29225500 G/A cg02153584 chr22:29168773 CCDC117 0.67 5.69 0.45 8.82e-8 Lymphocyte counts; TGCT cis rs7824557 0.806 rs6601573 chr8:11094751 A/G cg21775007 chr8:11205619 TDH -0.5 -4.55 -0.38 1.27e-5 Retinal vascular caliber; TGCT cis rs1018836 0.851 rs10808620 chr8:91622940 T/C cg16814680 chr8:91681699 NA -0.82 -8.6 -0.61 2.86e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2404602 0.647 rs10152247 chr15:76942252 T/G cg23625390 chr15:77176239 SCAPER -0.37 -4.67 -0.39 7.71e-6 Blood metabolite levels; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg00024416 chr22:24240387 NA -0.26 -4.97 -0.41 2.15e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6570726 0.643 rs9403735 chr6:145936591 C/T cg13319975 chr6:146136371 FBXO30 -0.53 -4.75 -0.39 5.62e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11679640 0.610 rs55687681 chr2:43114582 T/C cg00484711 chr2:42331922 NA -0.2 -4.54 -0.38 1.33e-5 White matter hyperintensity burden; TGCT cis rs13191362 1.000 rs34594856 chr6:163051845 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.5 0.61 5.17e-14 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs17767294 0.708 rs72847355 chr6:27825176 G/A cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs6430585 0.583 rs3769001 chr2:136626078 A/G cg07169764 chr2:136633963 MCM6 1.24 12.25 0.74 4.19e-23 Corneal structure; TGCT cis rs75686122 0.892 rs17234965 chr8:104729139 C/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs6684514 1.000 rs12122180 chr1:156244559 G/A cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg05552183 chr6:42928497 GNMT 0.54 4.75 0.39 5.47e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6429082 0.783 rs291385 chr1:235646613 T/C cg26050004 chr1:235667680 B3GALNT2 0.59 5.26 0.43 6.02e-7 Adiposity; TGCT cis rs6815814 0.950 rs11727978 chr4:38811051 T/A cg02016764 chr4:38805732 TLR1 -0.37 -5.85 -0.47 4.08e-8 Breast cancer; TGCT cis rs459571 0.959 rs467379 chr9:136905474 C/T cg14405625 chr9:136855902 VAV2 -0.33 -5.16 -0.42 9.42e-7 Platelet distribution width; TGCT cis rs9858542 0.537 rs67882627 chr3:49380441 A/T cg00383909 chr3:49044727 WDR6 0.7 4.75 0.39 5.48e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs10464366 0.544 rs2280667 chr7:39172228 A/C cg08835956 chr7:39171034 POU6F2 0.25 4.67 0.39 7.79e-6 IgG glycosylation; TGCT cis rs6582630 0.519 rs8189599 chr12:38280748 A/G cg26384229 chr12:38710491 ALG10B 0.87 7.54 0.56 8.43e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs3806843 0.546 rs246023 chr5:140333990 G/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs2204008 0.603 rs4397954 chr12:38089157 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.57 0.56 7.57e-12 Bladder cancer; TGCT cis rs7044106 0.500 rs56725168 chr9:123492576 T/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 5.54 0.45 1.69e-7 Hip circumference adjusted for BMI; TGCT cis rs10276381 1.000 rs7796417 chr7:28186119 G/C cg23620719 chr7:28220237 JAZF1 1.01 5.82 0.46 4.75e-8 Crohn's disease; TGCT cis rs7178572 0.568 rs1125617 chr15:77532711 A/G cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs11190604 1.000 rs2495739 chr10:102335507 C/T cg16342193 chr10:102329863 NA -0.43 -5.39 -0.44 3.43e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs904251 0.734 rs2797790 chr6:37447075 A/G cg25019722 chr6:37503610 NA 0.38 4.51 0.38 1.51e-5 Cognitive performance; TGCT cis rs2594989 0.837 rs2922348 chr3:11309784 T/C cg00170343 chr3:11313890 ATG7 0.7 4.97 0.41 2.21e-6 Circulating chemerin levels; TGCT cis rs669446 0.533 rs3862228 chr1:44196945 C/T cg12908607 chr1:44402522 ARTN -0.62 -7.25 -0.55 3.99e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs4319547 0.910 rs6416298 chr12:123002143 C/T cg05707623 chr12:122985044 ZCCHC8 -0.65 -4.8 -0.4 4.55e-6 Body mass index; TGCT cis rs10984561 0.881 rs1331594 chr9:122254439 T/C cg14242995 chr9:122249943 NA 0.72 5.82 0.46 4.75e-8 Pulmonary function decline; TGCT trans rs6762477 0.748 rs9831967 chr3:50217234 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.9 -9.91 -0.66 2.05e-17 Menarche (age at onset); TGCT cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs7959452 0.535 rs7308481 chr12:69659299 A/G cg14784868 chr12:69753453 YEATS4 0.69 7.03 0.53 1.23e-10 Blood protein levels; TGCT cis rs3784262 0.565 rs4646549 chr15:58358607 G/C cg12031962 chr15:58353849 ALDH1A2 -0.37 -5.11 -0.42 1.17e-6 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1461503 0.966 rs7110154 chr11:122843300 A/G cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs589448 0.934 rs554591 chr12:69753847 T/C cg20891283 chr12:69753455 YEATS4 0.91 10.33 0.68 1.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs6867032 0.527 rs4975777 chr5:1973324 G/T cg05184729 chr5:1962311 NA 0.27 4.54 0.38 1.32e-5 Gut microbiome composition (winter); TGCT cis rs2404602 0.709 rs11072591 chr15:76649562 A/G cg26408565 chr15:76604113 ETFA -0.4 -4.83 -0.4 4.01e-6 Blood metabolite levels; TGCT cis rs9512730 0.553 rs1040986 chr13:28051352 G/T cg04070771 chr13:27998621 GTF3A 0.55 4.8 0.4 4.44e-6 Schizophrenia; TGCT cis rs1577917 0.958 rs7382798 chr6:86559834 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs7100689 0.622 rs7897994 chr10:82133304 T/G cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs7824557 0.603 rs2736278 chr8:11219781 C/T cg21775007 chr8:11205619 TDH 0.64 5.93 0.47 2.83e-8 Retinal vascular caliber; TGCT cis rs17221829 0.733 rs12421371 chr11:89381008 T/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs34734847 1.000 rs56179458 chr12:121157535 G/A cg21892295 chr12:121157589 UNC119B -0.24 -5.71 -0.46 7.99e-8 Mean corpuscular volume; TGCT cis rs5769765 0.671 rs138841 chr22:50181960 C/A cg15316289 chr22:50310904 ALG12;CRELD2 0.33 4.69 0.39 7e-6 Schizophrenia; TGCT cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg20203395 chr5:56204925 C5orf35 -0.61 -5.3 -0.43 5.19e-7 Initial pursuit acceleration; TGCT trans rs4919669 0.546 rs4919647 chr10:104250754 A/C cg19053889 chr7:1098703 C7orf50;GPR146 0.51 6.77 0.52 4.63e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs7845219 0.544 rs4735331 chr8:95917958 C/T cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs7772486 0.790 rs7753696 chr6:146279098 G/T cg05347473 chr6:146136440 FBXO30 -0.55 -5.3 -0.43 5.08e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.98 -0.41 2.04e-6 Bipolar disorder; TGCT cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg13877915 chr19:58951672 ZNF132 0.91 11.55 0.72 2.15e-21 Uric acid clearance; TGCT cis rs2204008 0.678 rs61929520 chr12:38446800 T/C cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Bladder cancer; TGCT cis rs9814567 1.000 rs9819532 chr3:134288644 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.18 -0.64 1.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2033711 0.870 rs1051500 chr19:58944402 A/G cg13877915 chr19:58951672 ZNF132 0.89 11.28 0.71 9.7e-21 Uric acid clearance; TGCT cis rs797680 0.930 rs1474927 chr1:93570368 C/T cg17826107 chr1:92977322 EVI5 -0.22 -5.21 -0.42 7.58e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7666738 0.830 rs13118892 chr4:98968497 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs367615 0.918 rs10067984 chr5:108872684 C/T cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs35560671 chr4:99069095 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8084125 0.765 rs72981159 chr18:74945042 A/G cg05528293 chr18:74961138 GALR1 0.5 4.93 0.4 2.61e-6 Obesity-related traits; TGCT cis rs9393777 0.513 rs9379905 chr6:26630990 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.59 -5.33 -0.43 4.44e-7 Intelligence (multi-trait analysis); TGCT cis rs981844 0.712 rs1563461 chr4:154751913 C/T cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs2795502 1.000 rs3121278 chr10:43375646 G/T cg20628663 chr10:43360327 NA 0.48 5.6 0.45 1.33e-7 Blood protein levels; TGCT cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs7208859 0.623 rs11652358 chr17:29205480 T/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4722166 0.597 rs1554606 chr7:22768707 T/G cg26061582 chr7:22766209 IL6 0.58 7.49 0.56 1.1e-11 Lung cancer; TGCT cis rs734999 0.967 rs10910090 chr1:2496214 C/T cg18854424 chr1:2615690 NA 0.47 5.7 0.46 8.17e-8 Ulcerative colitis; TGCT cis rs9915657 0.834 rs2287131 chr17:70106227 T/C cg06234051 chr17:70120541 SOX9 -0.26 -5.37 -0.43 3.78e-7 Thyroid hormone levels; TGCT cis rs6933660 0.512 rs13202634 chr6:151800630 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.73 -4.52 -0.38 1.44e-5 Menarche (age at onset); TGCT cis rs617219 0.698 rs13177470 chr5:78495899 T/C cg05890484 chr5:78407552 BHMT 0.38 5.2 0.42 8.14e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs35306767 0.761 rs11253540 chr10:1011958 C/T cg20503657 chr10:835505 NA -0.57 -6.65 -0.51 8.44e-10 Eosinophil percentage of granulocytes; TGCT cis rs7575873 1 rs7575873 chr2:23962647 A/G cg08917208 chr2:24149416 ATAD2B 0.95 6.09 0.48 1.28e-8 Birth weight; TGCT cis rs7647973 0.848 rs4292260 chr3:49148890 T/C cg07636037 chr3:49044803 WDR6 0.77 6.08 0.48 1.34e-8 Menarche (age at onset); TGCT cis rs72843506 0.722 rs3764436 chr17:20013802 G/A cg18979559 chr17:20280153 CCDC144C -0.64 -4.8 -0.4 4.54e-6 Schizophrenia; TGCT cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.92 7.56 0.56 7.89e-12 Platelet count; TGCT cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.62 -5.63 -0.45 1.13e-7 Height; TGCT cis rs875971 0.964 rs778723 chr7:65829497 T/C cg18876405 chr7:65276391 NA 0.33 4.97 0.41 2.13e-6 Aortic root size; TGCT cis rs3617 0.539 rs9985365 chr3:52953844 A/G cg11645453 chr3:52864694 ITIH4 -0.28 -5.67 -0.45 9.6e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9393692 0.905 rs7761298 chr6:26278436 C/T cg00631329 chr6:26305371 NA -0.41 -6.09 -0.48 1.34e-8 Educational attainment; TGCT cis rs12579753 0.810 rs10862350 chr12:82156202 G/A cg07988820 chr12:82153109 PPFIA2 -0.62 -7.12 -0.54 7.57e-11 Resting heart rate; TGCT cis rs10089 1.000 rs10463838 chr5:127518305 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.79 7.56 0.56 7.96e-12 Ileal carcinoids; TGCT trans rs2727020 0.576 rs1814175 chr11:49559172 T/C cg15704280 chr7:45808275 SEPT13 -0.61 -6.78 -0.52 4.26e-10 Coronary artery disease; TGCT cis rs2841277 0.741 rs9672139 chr14:105408182 T/G cg19901468 chr14:105411992 AHNAK2 -0.27 -6.07 -0.48 1.47e-8 Rheumatoid arthritis; TGCT cis rs4638749 1.000 rs12477202 chr2:108867112 G/A cg06795125 chr2:108905320 SULT1C2 -0.37 -4.69 -0.39 6.95e-6 Blood pressure; TGCT cis rs7091068 0.616 rs7084701 chr10:95482249 A/G cg20715218 chr10:95462985 C10orf4 0.56 5.29 0.43 5.36e-7 Urinary tract infection frequency; TGCT cis rs7843479 0.511 rs4379446 chr8:21777595 C/G cg17168535 chr8:21777572 XPO7 0.76 7.55 0.56 8.38e-12 Mean corpuscular volume; TGCT cis rs6490294 0.808 rs7137270 chr12:112263402 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg05665937 chr4:1216051 CTBP1 0.25 4.75 0.39 5.64e-6 Obesity-related traits; TGCT trans rs7726839 0.540 rs57306627 chr5:597643 T/C cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs4851254 0.618 rs35300735 chr2:100667829 G/A cg07810366 chr2:100720526 AFF3 -0.49 -5.09 -0.42 1.28e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs66569888 0.754 rs6719028 chr2:106895212 T/C cg16099169 chr2:106886729 NA 0.43 4.81 0.4 4.32e-6 Facial morphology (factor 23); TGCT cis rs763014 0.932 rs7204439 chr16:661335 T/C cg09263875 chr16:632152 PIGQ 0.31 6.78 0.52 4.46e-10 Height; TGCT cis rs2120019 0.638 rs34492112 chr15:75294917 G/A cg09165964 chr15:75287851 SCAMP5 1.12 11.73 0.73 7.76e-22 Blood trace element (Zn levels); TGCT trans rs6089829 0.851 rs6089827 chr20:61668845 C/T cg23505145 chr19:12996616 KLF1 0.89 9.9 0.66 2.21e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs4555082 0.874 rs78923231 chr14:105754033 C/T cg01266790 chr14:105781312 PACS2 0.57 4.65 0.39 8.29e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs3796352 1.000 rs59583591 chr3:53119581 T/C cg15956490 chr3:53032818 SFMBT1 0.49 5.58 0.45 1.41e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs59197085 0.636 rs60389668 chr7:128452556 T/G cg00260937 chr7:128520193 KCP 0.47 4.9 0.4 2.92e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs7666738 0.830 rs6855393 chr4:99056534 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs116095464 0.558 rs9688136 chr5:229348 T/C cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs1580019 0.713 rs2167274 chr7:32524844 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.02 10.57 0.69 5.23e-19 Cognitive ability; TGCT cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7824557 0.872 rs2572417 chr8:11111462 A/T cg21775007 chr8:11205619 TDH -0.52 -4.92 -0.4 2.64e-6 Retinal vascular caliber; TGCT cis rs12142240 0.698 rs66972124 chr1:46807445 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs1799949 0.965 rs4239149 chr17:41328095 A/G cg23758822 chr17:41437982 NA -0.67 -6.73 -0.52 5.47e-10 Menopause (age at onset); TGCT cis rs9393777 0.513 rs6936555 chr6:26640886 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.59 -5.33 -0.43 4.44e-7 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.818 rs437978 chr6:145809134 A/G cg23711669 chr6:146136114 FBXO30 0.76 7.57 0.56 7.21e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs8064299 0.597 rs2016126 chr17:72784932 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.88 10.14 0.67 5.78e-18 Monocyte count; TGCT cis rs921968 0.541 rs576901 chr2:219424364 A/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs8177253 0.965 rs4854762 chr3:133499063 A/G cg20276088 chr3:133502917 NA 0.24 4.98 0.41 2.07e-6 Iron status biomarkers; TGCT cis rs6964587 1.000 rs1063243 chr7:91726927 A/C cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs1865760 0.551 rs9461230 chr6:26019240 G/C cg17042849 chr6:26104293 HIST1H4C -0.66 -5.91 -0.47 3.15e-8 Height; TGCT cis rs736408 0.812 rs746694 chr3:52826620 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.49 -0.37 1.58e-5 Bipolar disorder; TGCT cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs2439831 1.000 rs561863 chr15:43761352 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs9914988 0.943 rs7224870 chr17:27102620 A/G cg20469991 chr17:27169893 C17orf63 -0.66 -5.03 -0.41 1.65e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1215050 0.740 rs2555390 chr4:98999112 A/G cg17366294 chr4:99064904 C4orf37 -0.54 -5.81 -0.46 4.85e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2204008 0.775 rs12369238 chr12:38176051 A/G cg13010199 chr12:38710504 ALG10B 0.6 4.8 0.4 4.57e-6 Bladder cancer; TGCT cis rs7909074 0.831 rs2065466 chr10:45384047 T/C cg05187965 chr10:45406764 TMEM72 -0.27 -5.76 -0.46 6.14e-8 Mean corpuscular volume; TGCT cis rs1372520 0.748 rs1471484 chr4:90754313 C/T cg15133208 chr4:90757351 SNCA -0.46 -5.2 -0.42 8.04e-7 Neuroticism; TGCT cis rs7172809 0.561 rs74026925 chr15:77798709 A/G cg22256960 chr15:77711686 NA -0.51 -4.84 -0.4 3.83e-6 Glucose homeostasis traits; TGCT cis rs8017423 0.967 rs2401875 chr14:90688451 A/G cg04374321 chr14:90722782 PSMC1 0.77 8.02 0.58 6.73e-13 Mortality in heart failure; TGCT cis rs12210905 0.688 rs9368509 chr6:27379422 A/G cg08851530 chr6:28072375 NA -1.38 -6.42 -0.5 2.57e-9 Hip circumference adjusted for BMI; TGCT cis rs2730245 0.851 rs2657333 chr7:158728743 G/A cg11984989 chr7:158649758 WDR60 -0.95 -8.47 -0.61 5.89e-14 Height; TGCT cis rs2836950 0.527 rs2836948 chr21:40599677 T/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.64 -0.38 8.88e-6 Menarche (age at onset); TGCT cis rs9905704 0.671 rs28709536 chr17:57008912 C/A cg05425664 chr17:57184151 TRIM37 -0.57 -4.44 -0.37 1.97e-5 Testicular germ cell tumor; TGCT cis rs7267979 1.000 rs2257432 chr20:25271086 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1949733 0.958 rs2631731 chr4:8429817 A/G cg11789530 chr4:8429930 ACOX3 0.63 5.72 0.46 7.58e-8 Response to antineoplastic agents; TGCT cis rs9653442 0.545 rs1821827 chr2:100764717 T/C cg07810366 chr2:100720526 AFF3 -0.38 -5.62 -0.45 1.21e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs7726839 0.540 rs61731455 chr5:665295 A/G cg11887960 chr12:57824829 NA 1.15 9.91 0.66 2.07e-17 Obesity-related traits; TGCT cis rs9303401 0.659 rs16943326 chr17:57050365 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.6 6.14 0.48 1.01e-8 Cognitive test performance; TGCT cis rs6750795 0.502 rs11685196 chr2:232381298 A/G cg12810212 chr2:232379626 C2orf52 0.45 4.92 0.4 2.72e-6 Height; TGCT cis rs523522 0.924 rs11065150 chr12:120958875 T/G cg12219531 chr12:120966889 COQ5 0.83 7.36 0.55 2.24e-11 High light scatter reticulocyte count; TGCT cis rs60871478 0.636 rs4721834 chr7:896142 C/T cg15782153 chr7:917662 C7orf20 0.54 4.92 0.4 2.74e-6 Cerebrospinal P-tau181p levels; TGCT cis rs968451 0.951 rs5757622 chr22:39728861 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.91 8.88 0.62 6.32e-15 Primary biliary cholangitis; TGCT cis rs9926296 0.593 rs6500456 chr16:89888341 T/C cg26513180 chr16:89883248 FANCA 0.75 7.39 0.55 1.92e-11 Vitiligo; TGCT cis rs4727027 0.933 rs10238826 chr7:148830888 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs7824557 0.524 rs7835318 chr8:10953874 G/A cg15556689 chr8:8085844 FLJ10661 -0.85 -8.31 -0.6 1.39e-13 Retinal vascular caliber; TGCT cis rs477895 0.838 rs35090903 chr11:64000598 C/T cg23719950 chr11:63933701 MACROD1 -0.68 -5.65 -0.45 1.07e-7 Mean platelet volume; TGCT cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg03303774 chr4:1407052 NA -0.29 -5.08 -0.41 1.37e-6 Obesity-related traits; TGCT cis rs2153535 0.580 rs6918391 chr6:8461178 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9468199 0.510 rs72851161 chr6:28071123 A/G cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs4788570 0.566 rs8053992 chr16:71505495 G/A cg06353428 chr16:71660113 MARVELD3 -1.19 -7.71 -0.57 3.49e-12 Intelligence (multi-trait analysis); TGCT cis rs2463822 1.000 rs1406384 chr11:62083530 A/G cg06239285 chr11:62104954 ASRGL1 -0.93 -6.73 -0.52 5.56e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6570726 0.875 rs12524077 chr6:145866333 G/C cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.527 rs34835800 chr17:56764990 G/A cg25039879 chr17:56429692 SUPT4H1 0.53 4.55 0.38 1.25e-5 Cognitive test performance; TGCT cis rs12497850 0.865 rs7649458 chr3:48920127 C/T cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs7681440 0.904 rs12331318 chr4:90770255 A/G cg26578617 chr4:90757533 SNCA -0.47 -4.78 -0.39 4.95e-6 Dementia with Lewy bodies; TGCT cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs912057 0.833 rs1294436 chr6:6746166 G/C cg06612196 chr6:6737390 NA 0.37 4.7 0.39 6.75e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs61990749 0.597 rs12896026 chr14:78244436 A/G cg02301378 chr14:78227641 SNW1;C14orf178 0.61 4.52 0.38 1.43e-5 Fibroblast growth factor basic levels; TGCT cis rs6095298 0.595 rs35567324 chr20:47453054 T/C cg12307787 chr20:48099359 KCNB1 0.42 4.51 0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs6684514 1.000 rs12045339 chr1:156294211 C/T cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1371867 0.875 rs1788187 chr8:101336099 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg24250549 chr1:154909240 PMVK 0.66 6.5 0.5 1.73e-9 Prostate cancer; TGCT cis rs4824093 0.610 rs3761496 chr22:50246466 T/C cg20569369 chr22:51173646 NA 0.28 4.58 0.38 1.13e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6964587 0.933 rs10271174 chr7:91785970 A/G cg17063962 chr7:91808500 NA 0.89 9.55 0.65 1.55e-16 Breast cancer; TGCT cis rs813218 0.565 rs2449106 chr3:99602087 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.48 -5.49 -0.44 2.19e-7 Orofacial clefts; TGCT cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs35883536 0.626 rs12135243 chr1:101092955 G/A cg06223162 chr1:101003688 GPR88 -0.4 -7.07 -0.54 1.01e-10 Monocyte count; TGCT cis rs992157 0.835 rs4674282 chr2:219144230 A/T cg00012203 chr2:219082015 ARPC2 -0.79 -7.91 -0.58 1.22e-12 Colorectal cancer; TGCT cis rs10782582 0.609 rs1628063 chr1:76391646 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.53 4.66 0.39 7.96e-6 Daytime sleep phenotypes; TGCT cis rs12497850 0.797 rs61583136 chr3:49189195 C/T cg16497277 chr3:49208875 KLHDC8B -0.49 -4.47 -0.37 1.72e-5 Parkinson's disease; TGCT cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg03161606 chr19:29218774 NA 0.6 5.79 0.46 5.33e-8 Methadone dose in opioid dependence; TGCT cis rs60843830 0.661 rs7588043 chr2:104979 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.54 4.51 0.38 1.45e-5 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9322193 0.884 rs10872646 chr6:150067675 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs751728 0.965 rs9394168 chr6:33759701 T/A cg00334056 chr6:33755658 LEMD2 -0.25 -4.52 -0.38 1.44e-5 Crohn's disease; TGCT cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg04944784 chr2:26401820 FAM59B -0.72 -5.92 -0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs3008870 1.000 rs12740884 chr1:67459855 C/A cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs9457247 1.000 rs397713 chr6:167386714 G/A cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs6582630 0.555 rs12372536 chr12:38400864 C/G cg26384229 chr12:38710491 ALG10B 0.83 7.39 0.55 1.92e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs9311474 0.713 rs352171 chr3:52234203 A/G cg10802521 chr3:52805072 NEK4 -0.56 -6.01 -0.48 1.9e-8 Electroencephalogram traits; TGCT cis rs763121 0.853 rs1043441 chr22:39130964 C/T cg06022373 chr22:39101656 GTPBP1 0.79 7.32 0.55 2.68e-11 Menopause (age at onset); TGCT cis rs7714584 1.000 rs11748158 chr5:150226345 C/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs6952808 0.609 rs6970033 chr7:1948087 G/A cg22963979 chr7:1858916 MAD1L1 -0.37 -5.62 -0.45 1.22e-7 Bipolar disorder and schizophrenia; TGCT cis rs9549367 0.713 rs553316 chr13:113838015 A/G cg00898013 chr13:113819073 PROZ 0.53 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs670523 0.804 rs2364400 chr1:155997173 T/C cg05700447 chr1:155978627 NA -0.19 -4.62 -0.38 9.36e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7666738 0.830 rs1426664 chr4:98988264 A/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 0.791 rs2628166 chr17:28113123 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.81 -0.52 3.65e-10 Coffee consumption (cups per day); TGCT cis rs4372836 0.930 rs7589860 chr2:28967648 A/T cg09522027 chr2:28974177 PPP1CB -0.59 -5.15 -0.42 1e-6 Body mass index; TGCT trans rs6089829 1.000 rs6089828 chr20:61668998 C/T cg13615516 chr5:77269221 NA 0.7 8.72 0.62 1.53e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs17539620 0.624 rs62432739 chr6:154835926 A/G cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs6540559 1.000 rs6696825 chr1:209982372 A/G cg23283495 chr1:209979779 IRF6 0.67 5.59 0.45 1.35e-7 Cleft lip with or without cleft palate; TGCT cis rs6032067 0.516 rs57047308 chr20:43899974 T/C cg16667508 chr20:43936853 MATN4;RBPJL -0.38 -5.96 -0.47 2.38e-8 Blood protein levels; TGCT cis rs1018836 0.892 rs11776824 chr8:91553256 T/C cg16814680 chr8:91681699 NA -0.77 -8.22 -0.59 2.3e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs713587 0.713 rs11682135 chr2:25205377 G/A cg15423357 chr2:25149977 NA -0.58 -5.9 -0.47 3.16e-8 Body mass index in non-asthmatics; TGCT cis rs508618 1.000 rs508618 chr1:231532312 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -5.46 -0.44 2.46e-7 Red blood cell count; TGCT cis rs2228479 0.850 rs17226973 chr16:89825248 T/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs999943 0.846 rs9366826 chr6:33619184 C/G cg14003231 chr6:33640908 ITPR3 0.37 4.61 0.38 9.72e-6 Obesity (extreme); TGCT cis rs9383153 1.000 rs2237223 chr6:16329741 G/A cg03173502 chr6:15505345 JARID2 0.83 4.59 0.38 1.06e-5 Gambling; TGCT cis rs6459804 0.588 rs2109303 chr7:157506846 G/A cg14168080 chr7:157504135 PTPRN2 -0.4 -4.49 -0.37 1.58e-5 Bipolar disorder and schizophrenia; TGCT cis rs360798 0.512 rs360801 chr2:62955387 C/T cg17519650 chr2:63277830 OTX1 0.61 4.81 0.4 4.24e-6 Coronary artery disease; TGCT cis rs12497850 0.931 rs4974087 chr3:48919232 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg20887711 chr4:1340912 KIAA1530 0.76 6.31 0.49 4.41e-9 Longevity; TGCT cis rs7523273 0.606 rs2796268 chr1:207925192 G/A cg22525895 chr1:207977042 MIR29B2 0.54 9.18 0.64 1.18e-15 Schizophrenia; TGCT cis rs9393692 0.905 rs9379838 chr6:26277133 C/T cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.01e-7 Educational attainment; TGCT cis rs9916302 0.904 rs8068427 chr17:37511517 G/A cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs12712073 0.512 rs6710355 chr2:100699994 T/C cg22139774 chr2:100720529 AFF3 -0.4 -6.29 -0.49 4.87e-9 Intelligence (multi-trait analysis); TGCT cis rs250677 0.522 rs919730 chr5:148352401 T/C cg18129178 chr5:148520854 ABLIM3 0.4 5.14 0.42 1.04e-6 Breast cancer; TGCT cis rs6540559 1.000 rs6696825 chr1:209982372 A/G cg21951975 chr1:209979733 IRF6 0.71 5.98 0.47 2.21e-8 Cleft lip with or without cleft palate; TGCT cis rs57221529 0.766 rs72703075 chr5:592819 C/T cg16624210 chr5:671434 TPPP 0.45 4.9 0.4 2.9e-6 Lung disease severity in cystic fibrosis; TGCT cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg22105103 chr4:187893119 NA 0.34 4.62 0.38 9.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9640161 0.742 rs2108854 chr7:150017408 C/T cg10018233 chr7:150070692 REPIN1 -0.33 -4.68 -0.39 7.25e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs9303401 0.659 rs12935851 chr17:56600244 C/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs67478160 0.655 rs4900598 chr14:104281541 T/C cg26031613 chr14:104095156 KLC1 -0.63 -6.52 -0.51 1.61e-9 Schizophrenia; TGCT trans rs7824557 0.564 rs7834572 chr8:11236685 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs9911578 1.000 rs9892062 chr17:56976981 G/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs1215050 0.740 rs2555390 chr4:98999112 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -5.03 -0.41 1.69e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.830 rs1426662 chr4:98990319 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs115154263 chr4:119765307 G/A cg21605333 chr4:119757512 SEC24D 1.57 8.38 0.6 9.59e-14 Cannabis dependence symptom count; TGCT cis rs1865760 0.623 rs12216125 chr6:25997458 C/T cg17042849 chr6:26104293 HIST1H4C -0.72 -6.45 -0.5 2.28e-9 Height; TGCT cis rs9322193 0.923 rs35961297 chr6:149989065 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs3784262 0.739 rs1550574 chr15:58213368 G/T cg12031962 chr15:58353849 ALDH1A2 -0.54 -7.79 -0.57 2.3e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs10256972 0.967 rs1881122 chr7:1040946 A/T cg16145915 chr7:1198662 ZFAND2A -0.4 -4.78 -0.39 4.86e-6 Longevity;Endometriosis; TGCT cis rs72945132 0.882 rs55758686 chr11:70172204 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs116095464 0.558 rs2162870 chr5:228129 G/A cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs1766786 1.000 rs1766792 chr1:119465681 A/T cg03855857 chr1:119029635 NA -0.43 -4.47 -0.37 1.72e-5 Chin dimples; TGCT cis rs3772130 0.962 rs11707518 chr3:121496568 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs314370 0.951 rs13226502 chr7:100506381 C/T cg10426581 chr7:100472382 SRRT 1.02 11.08 0.71 2.94e-20 Resting heart rate; TGCT cis rs9291683 0.595 rs11731110 chr4:10037346 T/C cg11266682 chr4:10021025 SLC2A9 0.64 8.91 0.62 5.31e-15 Bone mineral density; TGCT cis rs10114408 0.959 rs7030088 chr9:96663432 A/C cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs875971 0.577 rs34888281 chr7:65585771 C/T cg18876405 chr7:65276391 NA -0.4 -6.01 -0.48 1.89e-8 Aortic root size; TGCT cis rs10256972 1.000 rs10256972 chr7:1039003 G/T cg16145915 chr7:1198662 ZFAND2A 0.39 4.71 0.39 6.54e-6 Longevity;Endometriosis; TGCT cis rs11148252 0.774 rs9596649 chr13:52934610 A/G cg00495681 chr13:53174319 NA -0.58 -5.69 -0.45 8.79e-8 Lewy body disease; TGCT cis rs3796352 1.000 rs11713859 chr3:53042080 C/A cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs17331151 0.573 rs3755801 chr3:52865798 G/A cg07884673 chr3:53033167 SFMBT1 0.48 5.54 0.45 1.76e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10466239 0.614 rs56214316 chr10:43861106 G/A cg08951903 chr10:44070173 ZNF239 -0.76 -4.46 -0.37 1.84e-5 Telomere length; TGCT cis rs9443645 0.901 rs4421161 chr6:79564219 A/G cg05283184 chr6:79620031 NA 0.21 4.7 0.39 6.81e-6 Intelligence (multi-trait analysis); TGCT cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.12 0.48 1.11e-8 Bipolar disorder; TGCT cis rs11577318 0.853 rs7416513 chr1:26647949 G/C cg04990556 chr1:26633338 UBXN11 -0.6 -4.96 -0.41 2.28e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg25767906 chr1:53392781 SCP2 -0.52 -6.19 -0.49 8.06e-9 Monocyte count; TGCT cis rs9457247 1.000 rs400063 chr6:167386592 C/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs3020736 0.500 rs6002618 chr22:42507859 G/C cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1568889 1.000 rs12802157 chr11:28060285 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs7267979 0.844 rs6115188 chr20:25432170 G/T cg16686733 chr20:25566563 NINL 0.52 4.93 0.4 2.62e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9399135 0.967 rs6925424 chr6:135313948 T/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs7104764 1.000 rs1128320 chr11:244167 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs9910055 0.762 rs4239142 chr17:42205876 A/G cg19774624 chr17:42201019 HDAC5 0.84 8.43 0.6 7.41e-14 Total body bone mineral density; TGCT cis rs17152411 1.000 rs11245423 chr10:126588435 C/A cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs7103648 0.669 rs11039332 chr11:47695840 G/A cg20307385 chr11:47447363 PSMC3 0.83 7.81 0.57 2.1e-12 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg10295955 chr4:187884368 NA -0.97 -14.62 -0.8 9.35e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs11098499 0.866 rs13125526 chr4:120288019 G/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs10791097 0.694 rs12361892 chr11:130744490 T/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7208859 0.623 rs1061343 chr17:29114276 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1878931 0.501 rs9302871 chr16:3415512 T/C cg22508957 chr16:3507546 NAT15 -0.38 -4.98 -0.41 2.1e-6 Body mass index (adult); TGCT cis rs250677 0.652 rs250680 chr5:148436024 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs7103648 0.545 rs6485795 chr11:47929846 G/A cg20307385 chr11:47447363 PSMC3 0.74 6.87 0.52 2.82e-10 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs4076943 0.500 rs4909973 chr11:11273949 C/T cg21653586 chr11:10530636 NA -0.49 -4.91 -0.4 2.76e-6 Post bronchodilator FEV1; TGCT cis rs1008375 1.000 rs2315561 chr4:17679695 C/T cg18681998 chr4:17616180 MED28 0.91 10.53 0.69 6.55e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13102973 0.682 rs7691622 chr4:135889689 T/C cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs7659604 0.540 rs7699289 chr4:122671553 G/A cg19748678 chr4:122722346 EXOSC9 -0.51 -4.93 -0.4 2.61e-6 Type 2 diabetes; TGCT cis rs600231 0.665 rs1621277 chr11:65221954 A/G cg17120908 chr11:65337727 SSSCA1 0.5 4.81 0.4 4.36e-6 Bone mineral density; TGCT cis rs9549260 0.755 rs2721044 chr13:41162225 C/T cg21288729 chr13:41239152 FOXO1 1.0 10.34 0.68 1.84e-18 Red blood cell count; TGCT cis rs7772486 0.701 rs697056 chr6:146003897 C/T cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs9457247 1.000 rs405553 chr6:167395058 A/G cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs617219 0.698 rs7706045 chr5:78507910 T/G cg09550809 chr5:78407562 BHMT 0.4 5.71 0.46 7.79e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7226408 0.901 rs72885252 chr18:34429398 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7666738 0.791 rs13111960 chr4:98976851 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7786808 0.552 rs12539355 chr7:158187565 C/T cg01191920 chr7:158217561 PTPRN2 -0.37 -5.44 -0.44 2.67e-7 Obesity-related traits; TGCT cis rs7659604 0.502 rs13128434 chr4:122672461 A/C cg19748678 chr4:122722346 EXOSC9 -0.51 -5.01 -0.41 1.86e-6 Type 2 diabetes; TGCT cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg03303774 chr4:1407052 NA -0.32 -4.92 -0.4 2.7e-6 Obesity-related traits; TGCT cis rs210152 0.531 rs3130023 chr6:33448862 A/G cg16739976 chr6:34101401 GRM4 -0.58 -4.75 -0.39 5.47e-6 Schizophrenia; TGCT cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs9611565 0.877 rs3817999 chr22:41747717 A/G cg13695892 chr22:41940480 POLR3H 0.91 9.67 0.66 8.18e-17 Vitiligo; TGCT cis rs875971 0.964 rs697969 chr7:65558478 C/A cg18876405 chr7:65276391 NA -0.35 -5.31 -0.43 4.85e-7 Aortic root size; TGCT cis rs6121246 0.954 rs6058470 chr20:30416827 A/T cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs4595586 0.545 rs7980848 chr12:39375166 G/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs782590 0.805 rs782578 chr2:55915904 A/C cg03859395 chr2:55845619 SMEK2 0.82 9.59 0.65 1.22e-16 Metabolic syndrome; TGCT cis rs752092 0.925 rs8032007 chr15:101790817 C/T cg19997662 chr15:101784653 CHSY1 0.27 5.04 0.41 1.58e-6 Corneal structure; TGCT cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg11062466 chr8:58055876 NA 0.4 4.62 0.38 9.62e-6 Developmental language disorder (linguistic errors); TGCT cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg03396347 chr1:1875803 NA -0.36 -6.51 -0.5 1.68e-9 Body mass index; TGCT cis rs6570726 0.738 rs6917199 chr6:145918320 G/A cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12220238 1.000 rs11000909 chr10:75944828 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3087591 0.922 rs11867284 chr17:29597464 G/A cg24425628 chr17:29625626 OMG;NF1 0.49 7.55 0.56 8.21e-12 Hip circumference; TGCT cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.81 0.4 4.35e-6 Schizophrenia; TGCT cis rs8072100 0.967 rs11871606 chr17:45732774 G/T cg08085267 chr17:45401833 C17orf57 0.43 4.81 0.4 4.28e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT trans rs1814175 0.817 rs10769613 chr11:49769692 G/A cg03929089 chr4:120376271 NA -0.69 -8.17 -0.59 3.03e-13 Height; TGCT cis rs881375 0.715 rs10985073 chr9:123643855 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.82e-7 Rheumatoid arthritis; TGCT cis rs651907 0.535 rs34263427 chr3:101507805 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg08219700 chr8:58056026 NA 0.41 4.94 0.41 2.47e-6 Developmental language disorder (linguistic errors); TGCT cis rs9926296 0.609 rs4785714 chr16:89798404 G/T cg04287289 chr16:89883240 FANCA -0.61 -6.06 -0.48 1.54e-8 Vitiligo; TGCT cis rs3617 0.503 rs9866243 chr3:52915219 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.52 -0.38 1.41e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs308403 0.600 rs13129352 chr4:123633736 G/T cg10495464 chr4:123653540 BBS12;LOC729338 0.72 6.52 0.51 1.57e-9 Blood protein levels; TGCT cis rs1577917 1.000 rs12201741 chr6:86602619 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.27 -0.43 5.73e-7 Response to antipsychotic treatment; TGCT trans rs696279 1.000 rs696279 chr7:16700798 A/G cg14841483 chr5:131310671 ACSL6 -0.38 -6.7 -0.52 6.51e-10 Mean platelet volume; TGCT cis rs4654899 0.965 rs6692244 chr1:21396886 C/A cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg06238570 chr21:40685208 BRWD1 0.73 6.66 0.51 8.12e-10 Cognitive function; TGCT cis rs9303401 0.527 rs2116450 chr17:56745561 C/T cg25039879 chr17:56429692 SUPT4H1 0.53 4.55 0.38 1.25e-5 Cognitive test performance; TGCT cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.07e-9 Type 2 diabetes; TGCT cis rs2046867 0.908 rs68142603 chr3:72790220 A/C cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1355223 0.583 rs1828298 chr11:34870439 A/G cg24088639 chr11:34937564 PDHX;APIP -0.51 -4.54 -0.38 1.31e-5 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs7804356 1.000 rs12536560 chr7:26822876 G/C cg03456212 chr7:26904342 SKAP2 -0.64 -4.88 -0.4 3.16e-6 Type 1 diabetes; TGCT cis rs2230307 0.536 rs560659 chr1:100523536 A/G cg24955406 chr1:100503596 HIAT1 -0.72 -4.64 -0.38 8.69e-6 Carotid intima media thickness; TGCT cis rs2688482 0.512 rs3103954 chr3:195516630 G/T cg13752114 chr3:195489708 MUC4 0.34 4.98 0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs9302001 0.881 rs12583303 chr13:95469027 C/T cg07483244 chr13:95358924 NA 0.37 4.84 0.4 3.86e-6 Panic disorder; TGCT cis rs9372498 0.505 rs9481789 chr6:118734320 A/C cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs7552404 0.924 rs1498317 chr1:76171984 A/C cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7584330 0.744 rs72620822 chr2:238379582 C/T cg14458575 chr2:238380390 NA 0.61 9.25 0.64 8.25e-16 Prostate cancer; TGCT cis rs1218582 0.688 rs2135219 chr1:154857217 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.63 -6.31 -0.49 4.49e-9 Prostate cancer; TGCT cis rs7119 0.689 rs12916833 chr15:77819778 G/A cg27398640 chr15:77910606 LINGO1 -0.26 -4.66 -0.39 7.98e-6 Type 2 diabetes; TGCT cis rs6815814 0.904 rs2101521 chr4:38811551 C/T cg02016764 chr4:38805732 TLR1 -0.29 -4.76 -0.39 5.31e-6 Breast cancer; TGCT cis rs1868673 0.545 rs9855441 chr3:150099659 C/A cg24290546 chr3:150134309 TSC22D2 -0.3 -4.75 -0.39 5.42e-6 Waist circumference; TGCT cis rs4665809 0.549 rs3828255 chr2:26413252 G/A cg26119090 chr2:26468346 HADHA;HADHB 0.96 5.78 0.46 5.81e-8 Gut microbiome composition (summer); TGCT cis rs7178572 0.568 rs12909924 chr15:77551445 T/G cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs6701037 0.512 rs4650716 chr1:175128711 C/A cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs9929218 0.551 rs2274240 chr16:68725486 A/G cg01251360 chr16:68772225 CDH1 -0.27 -5.02 -0.41 1.75e-6 Colorectal cancer; TGCT cis rs7394190 0.748 rs1057410 chr10:75574079 G/A cg07699608 chr10:75541558 CHCHD1 0.81 5.6 0.45 1.33e-7 Incident atrial fibrillation; TGCT cis rs1572072 0.545 rs765606 chr13:24163339 A/G cg06150803 chr13:24144257 TNFRSF19 -0.38 -4.48 -0.37 1.66e-5 Nasopharyngeal carcinoma; TGCT cis rs6570726 0.764 rs451108 chr6:145844309 T/C cg23711669 chr6:146136114 FBXO30 0.88 9.55 0.65 1.54e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.904 rs4511574 chr17:37532916 A/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.71 -0.39 6.66e-6 Glomerular filtration rate (creatinine); TGCT cis rs9916302 0.851 rs11078904 chr17:37650569 G/A cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs28595532 1.000 rs116030177 chr4:119650768 T/C cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs67460515 0.892 rs11929238 chr3:161045937 A/T cg03342759 chr3:160939853 NMD3 -0.48 -5.16 -0.42 9.65e-7 Parkinson's disease; TGCT cis rs17253792 0.822 rs17685078 chr14:56127202 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT trans rs4819388 0.709 rs2329712 chr21:45639245 C/T cg17383793 chr5:52405638 MOCS2 -0.71 -6.73 -0.52 5.65e-10 Celiac disease; TGCT cis rs11690935 0.632 rs34531723 chr2:172564094 A/C cg13550731 chr2:172543902 DYNC1I2 0.68 5.99 0.47 2.13e-8 Schizophrenia; TGCT cis rs12220238 0.822 rs7919517 chr10:76111355 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.17 0.48 9.08e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3806843 0.576 rs155360 chr5:140309016 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.43 -5.34 -0.43 4.19e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs3771570 1.000 rs73020143 chr2:242261240 T/A cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs13401104 0.716 rs10204147 chr2:237130344 A/C cg19324714 chr2:237145437 ASB18 0.46 5.03 0.41 1.69e-6 Educational attainment; TGCT cis rs2235642 0.717 rs2236269 chr16:1652614 T/A cg11375102 chr16:1583810 IFT140;TMEM204 -0.27 -4.66 -0.39 7.98e-6 Coronary artery disease; TGCT cis rs6964587 0.843 rs56075286 chr7:91731518 G/A cg17063962 chr7:91808500 NA 0.88 9.59 0.65 1.26e-16 Breast cancer; TGCT cis rs7552404 1.000 rs6672180 chr1:76123973 C/G cg22875332 chr1:76189707 ACADM 0.8 9.87 0.66 2.65e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2970818 0.764 rs11063182 chr12:4581371 A/G cg21129006 chr12:4023078 NA 0.3 4.67 0.39 7.76e-6 Phosphorus levels; TGCT cis rs7666738 1.000 rs13116475 chr4:99054843 C/T cg17366294 chr4:99064904 C4orf37 -0.76 -6.93 -0.53 1.99e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg10295955 chr4:187884368 NA -0.96 -13.98 -0.78 3.07e-27 Lobe attachment (rater-scored or self-reported); TGCT cis rs6912958 0.781 rs4464759 chr6:88282621 A/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs896854 0.516 rs12679044 chr8:95891356 C/A cg13393036 chr8:95962371 TP53INP1 -0.51 -6.29 -0.49 5e-9 Type 2 diabetes; TGCT cis rs9926296 1.000 rs9926296 chr16:89818089 A/G cg27121462 chr16:89883253 FANCA 0.71 7.27 0.55 3.46e-11 Vitiligo; TGCT cis rs2235642 0.859 rs12599207 chr16:1606445 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.63 -0.45 1.16e-7 Coronary artery disease; TGCT cis rs7772486 0.754 rs9386134 chr6:146145508 G/A cg13319975 chr6:146136371 FBXO30 -0.53 -4.76 -0.39 5.37e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2456568 0.802 rs11020585 chr11:93638493 A/C cg17595323 chr11:93583763 C11orf90 0.46 6.36 0.5 3.59e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9291683 0.655 rs3822242 chr4:10094904 T/C cg00071950 chr4:10020882 SLC2A9 -0.51 -5.66 -0.45 9.86e-8 Bone mineral density; TGCT cis rs2228479 0.867 rs34604714 chr16:89948985 A/G cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs5769765 0.955 rs8139758 chr22:50261123 G/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs9549260 0.755 rs7989711 chr13:41215696 C/T cg21288729 chr13:41239152 FOXO1 0.97 10.09 0.67 7.57e-18 Red blood cell count; TGCT cis rs1008375 0.932 rs6835077 chr4:17653285 A/T cg16339924 chr4:17578868 LAP3 0.66 5.52 0.44 1.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7208859 0.623 rs59447372 chr17:29057585 C/T cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3806843 0.576 rs155358 chr5:140297032 A/T cg09824255 chr5:140014002 CD14 0.25 4.48 0.37 1.69e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs11722228 0.964 rs10939614 chr4:9926613 T/C cg11266682 chr4:10021025 SLC2A9 -0.51 -5.76 -0.46 6.17e-8 Gout;Urate levels;Serum uric acid levels; TGCT cis rs853679 0.517 rs56364346 chr6:28050762 T/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs875971 0.964 rs60193905 chr7:65971260 A/G cg11764359 chr7:65958608 NA 0.59 5.29 0.43 5.45e-7 Aortic root size; TGCT cis rs9611565 0.608 rs2003816 chr22:42095140 T/G cg06481639 chr22:41940642 POLR3H 0.57 4.86 0.4 3.51e-6 Vitiligo; TGCT cis rs6089829 0.888 rs4809467 chr20:61671688 A/G cg08564027 chr20:61660810 NA 0.37 5.98 0.47 2.26e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs922182 0.595 rs9302232 chr15:64205358 C/T cg02919090 chr15:64263738 DAPK2 0.37 6.9 0.53 2.35e-10 Blood protein levels; TGCT cis rs9911578 0.935 rs2567912 chr17:56731270 T/C cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs2380220 0.576 rs7751219 chr6:96018915 G/A cg04719120 chr6:96025338 MANEA 0.73 5.45 0.44 2.66e-7 Behavioural disinhibition (generation interaction); TGCT cis rs12142240 0.698 rs12385696 chr1:46818836 A/G cg00530320 chr1:46809349 NSUN4 0.3 6.29 0.49 5.07e-9 Menopause (age at onset); TGCT cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg02458000 chr6:26745757 NA 0.55 5.25 0.43 6.28e-7 Intelligence (multi-trait analysis); TGCT cis rs12908161 0.959 rs17598603 chr15:85200211 C/G cg12863693 chr15:85201151 NMB -0.44 -5.38 -0.44 3.5e-7 Schizophrenia; TGCT cis rs9910055 0.659 rs227584 chr17:42225547 A/C cg19774624 chr17:42201019 HDAC5 -0.88 -10.92 -0.7 7.5e-20 Total body bone mineral density; TGCT cis rs6951245 0.638 rs4720486 chr7:1146764 G/A cg18402987 chr7:1209562 NA 0.47 4.68 0.39 7.37e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs68170813 0.652 rs74374590 chr7:107172470 G/A cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs9560113 0.573 rs9560133 chr13:112240013 C/A cg10483660 chr13:112241077 NA 0.36 5.67 0.45 9.63e-8 Menarche (age at onset); TGCT cis rs6840360 1.000 rs6849050 chr4:152599902 C/T cg17479576 chr4:152424074 FAM160A1 -0.5 -5.25 -0.43 6.5e-7 Intelligence (multi-trait analysis); TGCT cis rs804280 0.662 rs7826055 chr8:11611723 G/C cg26752888 chr8:11627280 NEIL2 0.6 4.92 0.4 2.66e-6 Myopia (pathological); TGCT cis rs11190604 0.945 rs11190573 chr10:102233172 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs736408 0.570 rs11130327 chr3:52793239 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.55 0.51 1.36e-9 Bipolar disorder; TGCT cis rs2456568 0.503 rs4254038 chr11:93666978 T/C cg17595323 chr11:93583763 C11orf90 -0.47 -5.84 -0.46 4.28e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg23758822 chr17:41437982 NA 0.78 7.29 0.55 3.14e-11 Menopause (age at onset); TGCT cis rs9660180 0.967 rs12040325 chr1:1702436 G/A cg23982607 chr1:1823379 GNB1 -0.55 -8.56 -0.61 3.62e-14 Body mass index; TGCT cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg17971929 chr21:40555470 PSMG1 0.68 6.1 0.48 1.28e-8 Cognitive function; TGCT cis rs1552244 0.554 rs34883592 chr3:10046165 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs4713118 0.662 rs9468275 chr6:28026136 G/T cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.765 rs7605734 chr2:99644068 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs11673344 0.542 rs826324 chr19:37505245 A/T cg08039142 chr19:36980659 ZNF566 0.52 4.84 0.4 3.71e-6 Obesity-related traits; TGCT cis rs909674 0.541 rs5750812 chr22:39793079 G/A cg11247378 chr22:39784982 NA -0.72 -10.08 -0.67 8.19e-18 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1023500 0.551 rs2301521 chr22:42423110 G/C cg15557168 chr22:42548783 NA -0.19 -4.82 -0.4 4.12e-6 Schizophrenia; TGCT cis rs185694 1.000 rs202101 chr13:30897337 A/G cg07600127 chr13:30881527 KATNAL1 -0.81 -6.53 -0.51 1.53e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs6582630 0.537 rs1829579 chr12:38420555 A/G cg26384229 chr12:38710491 ALG10B 0.84 7.7 0.57 3.77e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs2797160 1.000 rs1739367 chr6:126004720 G/T cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs4383453 0.539 rs4678018 chr3:123102044 G/A cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs1865760 0.622 rs9295685 chr6:26071725 G/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.96 0.41 2.25e-6 Height; TGCT cis rs36051895 0.632 rs7871515 chr9:5175288 A/G cg02405213 chr9:5042618 JAK2 0.75 10.62 0.69 3.84e-19 Pediatric autoimmune diseases; TGCT cis rs12681287 0.517 rs7462883 chr8:87526790 G/A cg27223183 chr8:87520930 FAM82B -0.96 -7.03 -0.53 1.21e-10 Caudate activity during reward; TGCT cis rs826838 0.967 rs11183022 chr12:38652519 G/A cg26384229 chr12:38710491 ALG10B 1.05 10.25 0.68 3.18e-18 Heart rate; TGCT cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg03806693 chr22:41940476 POLR3H -1.0 -10.21 -0.68 3.92e-18 Vitiligo; TGCT cis rs595982 0.527 rs55706579 chr19:49382969 G/A cg21252483 chr19:49399788 TULP2 -0.46 -6.92 -0.53 2.12e-10 Red cell distribution width; TGCT cis rs11252926 0.537 rs61836851 chr10:447231 T/C cg13477178 chr10:375248 DIP2C -0.24 -4.47 -0.37 1.71e-5 Psychosis in Alzheimer's disease; TGCT cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1158570 0.843 rs3057 chr8:131329837 C/T cg16277922 chr8:131349729 ASAP1 0.48 7.21 0.54 4.89e-11 Platelet count; TGCT cis rs2721195 0.845 rs1063739 chr8:145729727 C/A cg15857475 chr8:145742913 RECQL4;LRRC14 0.87 9.17 0.64 1.26e-15 Age at first birth; TGCT cis rs74233809 1.000 rs11191543 chr10:104824387 G/A cg05855489 chr10:104503620 C10orf26 0.82 4.61 0.38 9.67e-6 Birth weight; TGCT cis rs4851266 0.901 rs4851271 chr2:100833058 T/C cg22139774 chr2:100720529 AFF3 -0.34 -5.09 -0.42 1.28e-6 Educational attainment; TGCT cis rs7267979 1.000 rs2424712 chr20:25416942 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.869 rs742090 chr6:26415637 A/C cg15659132 chr6:26577336 NA -0.53 -5.58 -0.45 1.46e-7 Intelligence (multi-trait analysis); TGCT cis rs6663390 0.510 rs2267895 chr1:208081063 C/T cg03990033 chr1:208084030 CD34 0.73 6.41 0.5 2.77e-9 Facial morphology (factor 18); TGCT cis rs231513 0.655 rs231446 chr17:42005193 G/A cg26893861 chr17:41843967 DUSP3 -0.61 -5.11 -0.42 1.18e-6 Cognitive function; TGCT cis rs6450176 1.000 rs1445887 chr5:53299376 A/T ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg08280861 chr8:58055591 NA 0.36 4.97 0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs9868809 0.656 rs73078362 chr3:48703917 G/C cg07636037 chr3:49044803 WDR6 -1.0 -4.6 -0.38 1.04e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7156960 0.540 rs4903393 chr14:76734188 A/C cg13981132 chr14:76734493 NA -0.36 -5.63 -0.45 1.13e-7 Acute lymphoblastic leukemia (childhood); TGCT cis rs3806843 1.000 rs2240692 chr5:140183585 A/G cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2290405 0.527 rs6829987 chr4:932974 C/G cg04824913 chr4:887549 GAK -0.36 -4.56 -0.38 1.23e-5 Systemic sclerosis; TGCT cis rs4273100 0.688 rs12938803 chr17:19204432 A/C cg01534423 chr17:18965556 NA -0.81 -6.87 -0.52 2.78e-10 Schizophrenia; TGCT cis rs9534288 0.830 rs1126364 chr13:46633394 C/G cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs78707713 0.592 rs3829182 chr10:71251384 A/G cg14388049 chr10:71211838 TSPAN15 -0.4 -4.77 -0.39 5.01e-6 Venous thromboembolism; TGCT cis rs9929218 0.529 rs17715450 chr16:68729785 C/A cg01251360 chr16:68772225 CDH1 -0.26 -4.76 -0.39 5.4e-6 Colorectal cancer; TGCT cis rs500492 0.542 rs421245 chr16:1074458 G/C cg01366354 chr16:1075121 NA 0.36 5.23 0.43 6.99e-7 Polycystic ovary syndrome; TGCT cis rs10022260 1 rs10022260 chr4:83793921 C/T cg00595051 chr4:83955429 COPS4 -0.41 -5.25 -0.43 6.43e-7 Adult asthma; TGCT cis rs8180040 0.726 rs6774733 chr3:46991241 G/A cg27129171 chr3:47204927 SETD2 0.73 9.44 0.65 2.94e-16 Colorectal cancer; TGCT cis rs1570884 0.516 rs9316462 chr13:50176321 A/G cg08779649 chr13:50194554 NA 0.37 5.84 0.46 4.24e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs9467773 1.000 rs9393728 chr6:26509330 C/G cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT trans rs7726839 0.561 rs4957049 chr5:579080 C/A cg25482853 chr8:67687455 SGK3 1.05 9.29 0.64 6.67e-16 Obesity-related traits; TGCT cis rs71435601 0.628 rs540897 chr2:21383982 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs7809950 0.906 rs2395907 chr7:107253304 A/G cg23024343 chr7:107201750 COG5 0.35 5.57 0.45 1.48e-7 Coronary artery disease; TGCT cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.49e-10 Bipolar disorder; TGCT cis rs2439831 0.850 rs3742982 chr15:44176681 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.83 5.75 0.46 6.66e-8 Lung cancer in ever smokers; TGCT cis rs6700896 0.500 rs11208688 chr1:66081355 T/C cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs8103278 0.826 rs11669442 chr19:46374557 A/G cg14061069 chr19:46274453 DMPK -0.43 -5.82 -0.46 4.69e-8 Coronary artery disease; TGCT cis rs1538970 0.781 rs34768551 chr1:46020408 G/A cg05343316 chr1:45956843 TESK2 0.67 5.15 0.42 9.98e-7 Platelet count; TGCT cis rs425277 0.606 rs2257684 chr1:2077872 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.46 -0.37 1.81e-5 Height; TGCT cis rs7829975 0.517 rs12542733 chr8:8824858 G/T cg06636001 chr8:8085503 FLJ10661 -0.78 -7.01 -0.53 1.34e-10 Mood instability; TGCT cis rs10984561 0.881 rs59720051 chr9:122251073 G/T cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs9733 0.596 rs12089731 chr1:150647798 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs28595532 0.841 rs115918392 chr4:119610356 T/A cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.12e-11 Cannabis dependence symptom count; TGCT cis rs12421382 0.659 rs1837397 chr11:109389803 A/C cg16359550 chr11:109292809 C11orf87 0.41 4.57 0.38 1.17e-5 Schizophrenia; TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg25767906 chr1:53392781 SCP2 -0.54 -6.16 -0.48 9.25e-9 Monocyte count; TGCT cis rs6121246 0.697 rs6088864 chr20:30228157 G/A cg21427119 chr20:30132790 HM13 -0.37 -5.19 -0.42 8.51e-7 Mean corpuscular hemoglobin; TGCT cis rs1048238 0.506 rs10927866 chr1:16175317 C/T cg21385522 chr1:16154831 NA 0.61 7.01 0.53 1.34e-10 Systolic blood pressure; TGCT cis rs79349575 0.749 rs519537 chr17:46971140 G/A cg26022315 chr17:47021804 SNF8 0.47 4.55 0.38 1.28e-5 Type 2 diabetes; TGCT cis rs2836974 0.965 rs8134733 chr21:40683459 C/T cg06238570 chr21:40685208 BRWD1 0.74 6.54 0.51 1.45e-9 Cognitive function; TGCT cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg06634786 chr22:41940651 POLR3H -0.9 -8.72 -0.62 1.55e-14 Vitiligo; TGCT cis rs7666738 0.830 rs880470 chr4:98922522 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12220898 0.749 rs10732631 chr10:50485910 T/C cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs1580019 0.665 rs34147895 chr7:32531796 G/C cg06627557 chr7:32535165 LSM5;AVL9 1.03 10.62 0.69 3.91e-19 Cognitive ability; TGCT cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg13877915 chr19:58951672 ZNF132 0.92 11.68 0.72 1.01e-21 Uric acid clearance; TGCT cis rs13191362 0.507 rs2510207 chr6:163086592 T/C cg06582575 chr6:163149167 PACRG;PARK2 -0.6 -5.54 -0.45 1.75e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12497850 0.897 rs9681717 chr3:48872998 A/G cg05785598 chr3:49045655 WDR6 0.36 4.84 0.4 3.73e-6 Parkinson's disease; TGCT cis rs9915657 0.715 rs12952178 chr17:70107622 G/T cg06234051 chr17:70120541 SOX9 -0.24 -5.14 -0.42 1.03e-6 Thyroid hormone levels; TGCT cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg13665807 chr20:60559372 TAF4 -0.53 -5.39 -0.44 3.47e-7 Body mass index; TGCT cis rs1577917 1.000 rs6454513 chr6:86720049 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.64 5.14 0.42 1.06e-6 Response to antipsychotic treatment; TGCT cis rs7100689 0.577 rs2342813 chr10:82046302 T/G cg01528321 chr10:82214614 TSPAN14 0.67 6.45 0.5 2.31e-9 Post bronchodilator FEV1; TGCT cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg02187348 chr16:89574699 SPG7 0.49 4.72 0.39 6.35e-6 Multiple myeloma (IgH translocation); TGCT cis rs2544523 0.511 rs10929387 chr2:15912926 A/G cg26669897 chr2:15909070 NA 0.37 4.7 0.39 6.89e-6 Asthma or chronic obstructive pulmonary disease; TGCT cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg23205692 chr1:25664452 TMEM50A 0.47 4.97 0.41 2.22e-6 Erythrocyte sedimentation rate; TGCT cis rs11578119 0.898 rs10919424 chr1:170481571 G/A cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs16939607 1.000 rs16939607 chr8:79013333 A/G cg21244580 chr8:79934476 NA -0.47 -4.68 -0.39 7.33e-6 White blood cell count; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs10927875 0.541 rs1739841 chr1:16342727 A/G cg21385522 chr1:16154831 NA 0.46 4.75 0.39 5.5e-6 Dilated cardiomyopathy; TGCT cis rs9549367 0.737 rs71446680 chr13:113894846 C/T cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs734999 0.566 rs10797435 chr1:2534801 G/C cg18854424 chr1:2615690 NA 0.43 4.96 0.41 2.31e-6 Ulcerative colitis; TGCT cis rs1997103 0.911 rs17777 chr7:55380765 T/C cg17469321 chr7:55412551 NA 0.63 6.37 0.5 3.41e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg08859206 chr1:53392774 SCP2 0.46 7.11 0.54 8.24e-11 Monocyte count; TGCT cis rs10986311 0.775 rs7857897 chr9:127118550 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 0.2 4.87 0.4 3.36e-6 Vitiligo; TGCT cis rs4087296 0.671 rs11150459 chr16:82379577 A/G cg05453434 chr16:83371223 CDH13 0.31 4.44 0.37 1.93e-5 Bone mineral density; TGCT cis rs71435601 0.600 rs544655 chr2:21384441 G/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs903263 0.601 rs72711192 chr1:84562805 A/G cg09664975 chr1:84543551 PRKACB 0.5 4.87 0.4 3.36e-6 Breast cancer (male); TGCT cis rs1018836 0.923 rs2105967 chr8:91587522 A/G cg16814680 chr8:91681699 NA -0.81 -8.26 -0.6 1.84e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9457247 1.000 rs429083 chr6:167383972 T/C cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs3617 0.625 rs7612624 chr3:52893426 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.79 0.4 4.67e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs875971 1.000 rs7801282 chr7:65613687 C/T cg18876405 chr7:65276391 NA -0.32 -4.92 -0.4 2.69e-6 Aortic root size; TGCT cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg11890956 chr21:40555474 PSMG1 1.11 12.43 0.74 1.56e-23 Cognitive function; TGCT cis rs3785574 0.650 rs7406102 chr17:62004749 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.55 -4.87 -0.4 3.36e-6 Height; TGCT cis rs9611565 0.625 rs2076199 chr22:41903743 G/T cg06634786 chr22:41940651 POLR3H -0.76 -7.16 -0.54 6.31e-11 Vitiligo; TGCT cis rs4654899 0.931 rs2275468 chr1:21220375 T/G cg01072550 chr1:21505969 NA 0.49 7.73 0.57 3.2e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7439150 1.000 rs2042642 chr4:155487221 G/C cg22130008 chr4:155548532 NA -0.48 -5.99 -0.47 2.07e-8 Fibrinogen levels; TGCT cis rs739496 0.615 rs59905228 chr12:112181226 C/T cg10833066 chr12:111807467 FAM109A 0.36 4.67 0.39 7.74e-6 Platelet count; TGCT cis rs6570726 0.791 rs365869 chr6:145884751 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6701037 0.566 rs10753091 chr1:175134571 T/C cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs9379850 0.730 rs9393738 chr6:26620658 G/A cg15659132 chr6:26577336 NA -0.72 -5.29 -0.43 5.24e-7 Intelligence (multi-trait analysis); TGCT cis rs924607 1.000 rs11746907 chr5:598224 G/A cg04476341 chr5:669733 TPPP -0.26 -4.59 -0.38 1.05e-5 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs2070488 1.000 rs762317 chr3:38497659 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs2996428 0.667 rs11576900 chr1:3770914 A/G cg13057898 chr1:3703894 LRRC47 0.21 4.64 0.38 8.81e-6 Red cell distribution width; TGCT cis rs72700829 0.518 rs11548267 chr1:150238699 T/C cg18798344 chr1:149336151 NA 0.56 4.5 0.37 1.52e-5 Schizophrenia; TGCT trans rs7618501 0.572 rs7428430 chr3:50174184 C/T cg21659725 chr3:3221576 CRBN -0.66 -7.3 -0.55 3.08e-11 Intelligence (multi-trait analysis); TGCT cis rs6688613 0.685 rs4657613 chr1:166870878 A/G cg07049167 chr1:166818506 POGK 0.25 5.39 0.44 3.45e-7 Refractive astigmatism; TGCT cis rs2658782 0.547 rs3020065 chr11:93059899 A/G cg15737290 chr11:93063684 CCDC67 1.05 11.65 0.72 1.24e-21 Pulmonary function decline; TGCT cis rs11671005 0.651 rs35117909 chr19:58912906 G/A cg13877915 chr19:58951672 ZNF132 0.66 4.9 0.4 2.94e-6 Mean platelet volume; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg07157834 chr1:205819609 PM20D1 0.45 7.32 0.55 2.76e-11 Menarche (age at onset); TGCT cis rs711245 0.573 rs11899523 chr2:36800918 T/C cg09467607 chr2:36825704 FEZ2 0.33 4.67 0.39 7.72e-6 Height; TGCT cis rs4975709 0.610 rs4975705 chr5:1860359 T/C cg12288994 chr5:1860383 NA 0.24 4.65 0.39 8.46e-6 Cardiovascular disease risk factors; TGCT trans rs7726839 0.540 rs7558 chr5:660491 C/T cg25482853 chr8:67687455 SGK3 1.19 9.73 0.66 5.75e-17 Obesity-related traits; TGCT cis rs921968 0.541 rs7574429 chr2:219498759 T/G cg02176678 chr2:219576539 TTLL4 0.48 6.73 0.52 5.53e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg20887711 chr4:1340912 KIAA1530 0.54 5.03 0.41 1.69e-6 Longevity; TGCT cis rs587847 0.522 rs582122 chr15:37687805 A/T cg22444584 chr15:37174661 LOC145845 -0.31 -4.61 -0.38 1e-5 Intraocular pressure; TGCT cis rs1062177 0.724 rs2915828 chr5:151118121 G/A cg12924095 chr5:151150029 G3BP1 -0.34 -4.97 -0.41 2.17e-6 Preschool internalizing problems; TGCT cis rs10464366 0.912 rs6979668 chr7:39104228 G/A cg18850127 chr7:39170497 POU6F2 0.21 4.5 0.37 1.55e-5 IgG glycosylation; TGCT cis rs9902453 0.689 rs56788338 chr17:28186557 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.54 0.61 4.08e-14 Coffee consumption (cups per day); TGCT cis rs13256369 0.951 rs12679360 chr8:8566269 G/T cg17143192 chr8:8559678 CLDN23 -0.55 -5.52 -0.44 1.88e-7 Obesity-related traits; TGCT cis rs739496 0.615 rs847895 chr12:112118576 T/C cg10833066 chr12:111807467 FAM109A 0.37 4.79 0.39 4.76e-6 Platelet count; TGCT cis rs7617773 0.963 rs9822496 chr3:48181333 T/C cg11946769 chr3:48343235 NME6 0.59 5.3 0.43 5.19e-7 Coronary artery disease; TGCT cis rs17376456 0.542 rs2084916 chr5:93194961 A/T cg21475434 chr5:93447410 FAM172A -0.7 -5.15 -0.42 1.02e-6 Diabetic retinopathy; TGCT cis rs2760061 0.583 rs708110 chr1:228190805 T/A cg18477163 chr1:228402036 OBSCN 0.35 7.06 0.54 1.03e-10 Diastolic blood pressure; TGCT cis rs317865 0.867 rs56106162 chr4:16159062 G/A cg04764131 chr4:16228633 TAPT1;FLJ39653 0.67 4.62 0.38 9.31e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs11785400 0.793 rs4403386 chr8:143736770 C/G cg10596483 chr8:143751796 JRK 0.54 5.44 0.44 2.7e-7 Schizophrenia; TGCT cis rs2239547 0.562 rs35380116 chr3:52979178 A/G cg11645453 chr3:52864694 ITIH4 -0.32 -5.28 -0.43 5.48e-7 Schizophrenia; TGCT trans rs6089829 0.962 rs6062776 chr20:61663736 A/G cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs6429082 0.683 rs868815 chr1:235584543 C/G cg26050004 chr1:235667680 B3GALNT2 -0.56 -4.95 -0.41 2.41e-6 Adiposity; TGCT cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg23758822 chr17:41437982 NA 0.72 6.77 0.52 4.51e-10 Menopause (age at onset); TGCT cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg07507251 chr3:52567010 NT5DC2 0.48 7.06 0.54 1.05e-10 Bipolar disorder; TGCT cis rs151997 0.962 rs27936 chr5:50181418 T/A cg06027927 chr5:50259733 NA 0.46 4.61 0.38 9.69e-6 Callous-unemotional behaviour; TGCT cis rs9325144 0.647 rs34311455 chr12:39060889 C/T cg10518543 chr12:38710700 ALG10B -0.48 -4.47 -0.37 1.77e-5 Morning vs. evening chronotype; TGCT cis rs9814567 0.752 rs6764764 chr3:134331167 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.78 6.94 0.53 1.91e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs57221529 0.766 rs72706610 chr5:561111 G/A cg11887960 chr12:57824829 NA 1.16 9.59 0.65 1.25e-16 Lung disease severity in cystic fibrosis; TGCT cis rs2072499 0.966 rs1137703 chr1:156184458 T/C cg06970220 chr1:156163860 SLC25A44 0.67 5.98 0.47 2.22e-8 Testicular germ cell tumor; TGCT cis rs2657888 0.529 rs11171862 chr12:56871314 C/T cg23002907 chr12:56915593 RBMS2 -0.42 -5.69 -0.45 8.68e-8 Adiponectin levels; TGCT cis rs950169 1.000 rs62026530 chr15:84775840 G/T cg17173187 chr15:85201210 NMB 0.47 5.23 0.43 7.01e-7 Schizophrenia; TGCT cis rs11785400 0.793 rs4457308 chr8:143733922 G/A cg10596483 chr8:143751796 JRK 0.55 5.47 0.44 2.41e-7 Schizophrenia; TGCT cis rs7772486 0.875 rs2748498 chr6:146319166 C/G cg23711669 chr6:146136114 FBXO30 0.87 9.38 0.64 4.09e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.941 rs11126336 chr2:26245931 C/T cg27170947 chr2:26402098 FAM59B -0.4 -4.66 -0.39 8.04e-6 Gut microbiome composition (summer); TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg16325326 chr1:53192061 ZYG11B 0.59 6.41 0.5 2.81e-9 Monocyte count; TGCT cis rs10986311 0.802 rs2416 chr9:127113660 A/G cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.72 0.39 6.24e-6 Vitiligo; TGCT cis rs2228479 0.850 rs62054638 chr16:89821131 G/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs9858542 1.000 rs34762726 chr3:49689210 G/A cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs12286929 0.576 rs2275997 chr11:115100186 A/G cg16269184 chr11:114127960 NA -0.2 -4.86 -0.4 3.55e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12142240 0.738 rs10489769 chr1:46806703 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.95 0.47 2.58e-8 Menopause (age at onset); TGCT cis rs2964802 0.505 rs7447014 chr5:10814212 T/C cg14521931 chr5:10832172 NA -0.28 -4.61 -0.38 9.72e-6 Major depressive disorder;Recurrent major depressive disorder; TGCT trans rs208520 0.874 rs208473 chr6:66917265 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -9.95 -0.67 1.64e-17 Exhaled nitric oxide output; TGCT cis rs1691799 0.899 rs1168318 chr12:66745269 A/G cg16791601 chr12:66731901 HELB 0.28 5.98 0.47 2.19e-8 White blood cell count (basophil); TGCT cis rs9929218 0.954 rs17715799 chr16:68830511 A/T cg03880890 chr16:69439245 NA -0.22 -4.47 -0.37 1.73e-5 Colorectal cancer; TGCT cis rs7681440 0.647 rs1442133 chr4:90819195 C/T cg20003494 chr4:90757398 SNCA -0.53 -4.73 -0.39 5.98e-6 Dementia with Lewy bodies; TGCT cis rs2562456 0.917 rs11085463 chr19:21751302 G/T cg25650185 chr19:21324782 ZNF431 -0.63 -5.58 -0.45 1.43e-7 Pain; TGCT cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg18252515 chr7:66147081 NA -1.31 -8.17 -0.59 2.99e-13 Diabetic kidney disease; TGCT trans rs561341 1.000 rs564714 chr17:30318404 C/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.64 -0.38 8.79e-6 Menarche (age at onset); TGCT cis rs7726839 0.540 rs61580655 chr5:597564 A/G cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg03517284 chr6:25882590 NA -0.6 -5.33 -0.43 4.57e-7 Intelligence (multi-trait analysis); TGCT cis rs11096990 0.593 rs6531700 chr4:39270885 T/G cg20847110 chr4:39482781 LOC401127 -0.16 -4.53 -0.38 1.36e-5 Cognitive function; TGCT cis rs4076943 0.603 rs7941021 chr11:11271212 T/C cg21653586 chr11:10530636 NA 0.5 5.07 0.41 1.43e-6 Post bronchodilator FEV1; TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg11965913 chr1:205819406 PM20D1 0.48 6.6 0.51 1.07e-9 Menarche (age at onset); TGCT cis rs4808199 0.901 rs12973258 chr19:19488718 T/C cg03709012 chr19:19516395 GATAD2A 1.0 7.84 0.58 1.77e-12 Nonalcoholic fatty liver disease; TGCT cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.92 11.52 0.72 2.52e-21 Colorectal cancer; TGCT cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs921968 0.591 rs13421421 chr2:219519286 A/G cg02176678 chr2:219576539 TTLL4 0.43 6.07 0.48 1.44e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs12477438 0.765 rs62156363 chr2:99693324 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs7395581 0.918 rs7124955 chr11:47315274 A/T cg20307385 chr11:47447363 PSMC3 -0.53 -4.46 -0.37 1.83e-5 HDL cholesterol; TGCT cis rs1215050 0.655 rs3974902 chr4:98644254 C/T cg05340658 chr4:99064831 C4orf37 -0.44 -5.25 -0.43 6.25e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1577917 0.958 rs2100109 chr6:86544926 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs7091068 0.532 rs554062 chr10:95399535 T/A cg20715218 chr10:95462985 C10orf4 -0.49 -6.01 -0.47 1.96e-8 Urinary tract infection frequency; TGCT cis rs6424115 0.800 rs2229581 chr1:24201094 G/C cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs9435341 0.930 rs2232015 chr1:107599258 A/T cg09367891 chr1:107599246 PRMT6 0.64 5.58 0.45 1.43e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs208520 0.661 rs150263 chr6:66777620 T/C cg07460842 chr6:66804631 NA -0.95 -9.97 -0.67 1.53e-17 Exhaled nitric oxide output; TGCT cis rs2224391 1.000 rs2773320 chr6:5261681 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.8 -6.12 -0.48 1.13e-8 Height; TGCT cis rs4383453 0.539 rs12631979 chr3:123097710 A/G cg04890266 chr3:123102914 ADCY5 -0.5 -8.34 -0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs2688608 0.560 rs10128354 chr10:75470045 T/C cg04320760 chr10:75533139 FUT11 -0.38 -5.86 -0.47 3.9e-8 Inflammatory bowel disease; TGCT cis rs904251 0.861 rs1757173 chr6:37486952 A/C cg01843034 chr6:37503916 NA -0.52 -6.29 -0.49 4.88e-9 Cognitive performance; TGCT cis rs9796 0.774 rs28866311 chr15:41442195 T/G cg18705301 chr15:41695430 NDUFAF1 -0.51 -6.56 -0.51 1.33e-9 Menopause (age at onset); TGCT cis rs2594989 0.733 rs9876898 chr3:11567961 T/C cg00170343 chr3:11313890 ATG7 -0.66 -5.26 -0.43 6.1e-7 Circulating chemerin levels; TGCT cis rs6089829 0.962 rs2277769 chr20:61666805 C/T cg03213289 chr20:61660250 NA 0.69 10.06 0.67 9.06e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs6952808 0.500 rs3800902 chr7:2144378 C/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.72 -0.39 6.16e-6 Bipolar disorder and schizophrenia; TGCT cis rs7017914 0.905 rs2732095 chr8:71919946 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs7666738 0.830 rs17558151 chr4:99048699 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.791 rs621382 chr6:145799144 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.84 0.66 3.1e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7100689 0.622 rs4536152 chr10:82119242 C/T cg01528321 chr10:82214614 TSPAN14 0.81 7.75 0.57 2.9e-12 Post bronchodilator FEV1; TGCT cis rs6831352 0.918 rs17218560 chr4:100060794 C/T cg12011299 chr4:100065546 ADH4 0.4 4.75 0.39 5.55e-6 Alcohol dependence; TGCT cis rs7772486 0.754 rs857881 chr6:145970793 C/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.61 -0.38 9.92e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9560113 1.000 rs9555811 chr13:112181532 A/C cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs7017914 0.840 rs2732099 chr8:71921050 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.05 -0.41 1.52e-6 Bone mineral density; TGCT cis rs7980687 0.550 rs1727324 chr12:123698603 A/T cg00376283 chr12:123451042 ABCB9 0.73 5.1 0.42 1.26e-6 Height;Educational attainment;Head circumference (infant); TGCT cis rs6430585 0.702 rs746857 chr2:136554890 G/A cg07169764 chr2:136633963 MCM6 -1.18 -10.81 -0.7 1.33e-19 Corneal structure; TGCT cis rs3761847 0.622 rs10435888 chr9:123819603 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 4.52 0.38 1.42e-5 Rheumatoid arthritis; TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg16325326 chr1:53192061 ZYG11B 0.63 7.34 0.55 2.51e-11 Monocyte count; TGCT cis rs9733 0.596 rs2867300 chr1:150666990 C/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.66 0.39 8.17e-6 Tonsillectomy; TGCT cis rs62103177 0.608 rs4442895 chr18:77826399 C/G cg20368463 chr18:77673604 PQLC1 -0.45 -4.65 -0.39 8.28e-6 Opioid sensitivity; TGCT trans rs208520 0.802 rs4710315 chr6:66887594 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -10.37 -0.68 1.58e-18 Exhaled nitric oxide output; TGCT cis rs7552404 0.924 rs7550974 chr1:76204185 A/G cg03433033 chr1:76189801 ACADM 0.82 9.91 0.66 2.05e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1670533 1.000 rs7673898 chr4:1056569 C/A cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs7584330 0.955 rs7581882 chr2:238390745 T/C cg14458575 chr2:238380390 NA 0.48 7.42 0.55 1.66e-11 Prostate cancer; TGCT cis rs12950390 0.853 rs66471233 chr17:45867086 C/T cg06532163 chr17:45867833 NA 0.37 5.96 0.47 2.45e-8 IgG glycosylation; TGCT cis rs4727027 0.833 rs2107846 chr7:148832774 G/A cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3733585 0.699 rs7657340 chr4:9966772 A/T cg11266682 chr4:10021025 SLC2A9 -0.59 -7.87 -0.58 1.53e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6988636 1.000 rs16898084 chr8:124190377 A/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs858239 0.632 rs6952947 chr7:23121042 C/G cg05602783 chr7:23145260 KLHL7 0.6 5.02 0.41 1.76e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs12188164 0.965 rs11739543 chr5:443676 G/A cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs7772486 0.558 rs9497403 chr6:146054695 T/G cg05347473 chr6:146136440 FBXO30 -0.65 -5.89 -0.47 3.34e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs1385374 0.502 rs923077 chr12:129276708 C/A cg09035930 chr12:129282057 SLC15A4 0.55 4.76 0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs4851266 1.000 rs11686372 chr2:100827907 C/A cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs651907 0.557 rs1031710 chr3:101463895 C/T cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.78 -0.52 4.35e-10 Colorectal cancer; TGCT cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg03264133 chr6:25882463 NA 0.48 5.13 0.42 1.1e-6 Blood metabolite levels; TGCT cis rs838147 0.563 rs2638282 chr19:49213833 G/A cg00822241 chr19:49201468 FUT2 0.29 4.59 0.38 1.08e-5 Dietary macronutrient intake; TGCT cis rs950169 0.922 rs4842946 chr15:84942331 G/A cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg06873352 chr17:61820015 STRADA -0.53 -6.18 -0.49 8.61e-9 Prudent dietary pattern; TGCT cis rs2549003 1.000 rs3846732 chr5:131816087 T/C cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs4766566 0.704 rs10774617 chr12:111755178 T/C cg10833066 chr12:111807467 FAM109A 0.36 6.36 0.5 3.44e-9 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs763121 0.853 rs35522482 chr22:39063015 C/A cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs7044106 0.734 rs12553070 chr9:123485266 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.91 0.4 2.84e-6 Hip circumference adjusted for BMI; TGCT cis rs2033711 0.936 rs882609 chr19:58991479 G/A cg13877915 chr19:58951672 ZNF132 0.79 8.3 0.6 1.5e-13 Uric acid clearance; TGCT cis rs1371867 0.846 rs1613453 chr8:101244215 G/T cg06636551 chr8:101224915 SPAG1 0.49 6.63 0.51 9.45e-10 Atrioventricular conduction; TGCT cis rs12497850 1.000 rs10865952 chr3:48744484 A/G cg18654377 chr3:49208889 KLHDC8B -0.44 -6.06 -0.48 1.52e-8 Parkinson's disease; TGCT cis rs2153535 0.601 rs1928183 chr6:8530018 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs28493229 0.522 rs2233152 chr19:41281016 C/T cg23743927 chr19:41304969 EGLN2 -0.74 -4.67 -0.39 7.7e-6 Kawasaki disease; TGCT cis rs78487399 0.808 rs74608713 chr2:43763539 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -4.66 -0.39 8.17e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs742320 0.756 rs4984925 chr16:839996 T/C cg03433313 chr16:819064 MIR662 -0.52 -7.15 -0.54 6.46e-11 Mean corpuscular volume; TGCT trans rs10506458 0.915 rs1009540 chr12:63414872 C/A cg22491629 chr6:157744540 C6orf35 -0.99 -8.57 -0.61 3.45e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs739401 0.611 rs2239900 chr11:3030992 C/T cg05729581 chr11:3078854 CARS -0.54 -5.12 -0.42 1.13e-6 Longevity; TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs7772486 0.774 rs2247571 chr6:146219533 T/A cg05347473 chr6:146136440 FBXO30 0.5 4.58 0.38 1.1e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.554 rs58020561 chr3:10054682 A/G cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs6089829 0.889 rs6122348 chr20:61663921 C/T cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs9522267 0.535 rs9522299 chr13:112236013 C/A cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs3125734 0.607 rs7923556 chr10:64024648 A/G cg19640130 chr10:64028056 RTKN2 -0.4 -5.17 -0.42 9.02e-7 Rheumatoid arthritis; TGCT cis rs1862618 0.671 rs2034244 chr5:56242774 T/C cg24531977 chr5:56204891 C5orf35 0.68 7.22 0.54 4.65e-11 Initial pursuit acceleration; TGCT cis rs9910055 0.529 rs228765 chr17:42186422 C/T cg19774624 chr17:42201019 HDAC5 0.75 7.12 0.54 7.85e-11 Total body bone mineral density; TGCT cis rs3772130 0.886 rs9825248 chr3:121568711 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.5 4.48 0.37 1.65e-5 Cognitive performance; TGCT cis rs4972806 0.849 rs1542180 chr2:177028767 C/T cg14324370 chr2:177042789 NA 0.73 6.98 0.53 1.59e-10 IgG glycosylation; TGCT cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.05 0.48 1.59e-8 Alzheimer's disease; TGCT trans rs1974653 0.672 rs7284918 chr22:20086737 T/C cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg02458000 chr6:26745757 NA 0.51 4.73 0.39 5.91e-6 Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs7645611 chr3:53125297 G/C cg27565382 chr3:53032988 SFMBT1 0.41 4.63 0.38 9.1e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7044106 0.762 rs10739570 chr9:123381222 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.56 6.06 0.48 1.53e-8 Hip circumference adjusted for BMI; TGCT cis rs1801251 1.000 rs4973053 chr2:233670099 G/A cg25237894 chr2:233734115 C2orf82 -0.31 -5.49 -0.44 2.17e-7 Coronary artery disease; TGCT cis rs116095464 0.558 rs10068203 chr5:206618 C/T cg22857025 chr5:266934 NA -0.35 -6.63 -0.51 9.12e-10 Breast cancer; TGCT cis rs116095464 0.681 rs9687745 chr5:229309 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs7119 0.700 rs57471224 chr15:77888169 A/G cg27398640 chr15:77910606 LINGO1 0.33 6.85 0.52 3.09e-10 Type 2 diabetes; TGCT cis rs9899728 0.706 rs7210092 chr17:73021600 A/G cg00012762 chr17:72744649 SLC9A3R1 -1.0 -4.48 -0.37 1.67e-5 Alzheimer's disease or small vessel stroke; TGCT cis rs1008375 0.966 rs10939735 chr4:17578891 A/G cg18681998 chr4:17616180 MED28 0.85 8.18 0.59 2.86e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs208515 0.525 rs12204706 chr6:66669930 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.9 -9.83 -0.66 3.19e-17 Exhaled nitric oxide levels; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs1843834 0.574 rs6436499 chr2:225456551 A/T cg22455342 chr2:225449267 CUL3 1.01 10.65 0.69 3.37e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs1008375 1.000 rs11724495 chr4:17621310 G/A cg18681998 chr4:17616180 MED28 1.0 11.31 0.71 8.26e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11264213 0.901 rs72661628 chr1:36406547 A/G cg27506609 chr1:36549197 TEKT2 0.42 4.72 0.39 6.2e-6 Schizophrenia; TGCT trans rs17685 0.712 rs10235086 chr7:75833138 G/T cg19862616 chr7:65841803 NCRNA00174 0.48 8.22 0.59 2.25e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs3820068 0.608 rs7516683 chr1:16020502 A/G cg05660106 chr1:15850417 CASP9 -0.65 -5.99 -0.47 2.09e-8 Systolic blood pressure; TGCT cis rs9325144 0.581 rs2730929 chr12:38942739 T/C cg13010199 chr12:38710504 ALG10B -0.58 -5.46 -0.44 2.46e-7 Morning vs. evening chronotype; TGCT cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.62 -6.91 -0.53 2.28e-10 Blood metabolite levels; TGCT cis rs9436747 0.615 rs6676495 chr1:66052117 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.04 0.41 1.59e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs1524927 0.966 rs12704871 chr7:96334274 C/T cg03808172 chr7:96339361 SHFM1 -0.49 -5.08 -0.41 1.36e-6 Total body bone mineral density; TGCT cis rs6669384 0.774 rs12141901 chr1:208031234 G/A cg22525895 chr1:207977042 MIR29B2 -0.38 -5.35 -0.43 4.04e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs1475911 0.708 rs11701371 chr21:43523972 C/G cg19766460 chr21:43528205 UMODL1;C21orf128 0.65 9.67 0.66 8.13e-17 IgG glycosylation; TGCT cis rs896854 1.000 rs896854 chr8:95960511 T/C cg16049864 chr8:95962084 TP53INP1 -0.76 -11.14 -0.71 2.13e-20 Type 2 diabetes; TGCT cis rs9527 0.590 rs10509764 chr10:104776475 G/A cg15744005 chr10:104629667 AS3MT -0.42 -4.92 -0.4 2.74e-6 Arsenic metabolism; TGCT cis rs28595532 0.920 rs56042726 chr4:119751777 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs12967678 1 rs12967678 chr18:12805388 G/A cg23598886 chr18:12777645 NA -0.64 -5.03 -0.41 1.67e-6 Selective IgA deficiency; TGCT cis rs10504229 0.906 rs2270609 chr8:58194684 G/A cg08280861 chr8:58055591 NA 0.35 4.47 0.37 1.72e-5 Developmental language disorder (linguistic errors); TGCT cis rs12681287 0.640 rs6992287 chr8:87418960 G/A cg27223183 chr8:87520930 FAM82B 0.89 6.36 0.5 3.45e-9 Caudate activity during reward; TGCT cis rs9611565 0.649 rs738422 chr22:42123399 C/T cg13695892 chr22:41940480 POLR3H 0.83 8.18 0.59 2.79e-13 Vitiligo; TGCT cis rs7666738 0.800 rs2865988 chr4:99067807 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2288884 1.000 rs17779301 chr19:52539243 A/G cg15405931 chr19:52693188 PPP2R1A 0.68 4.7 0.39 6.9e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs10875746 0.624 rs11168498 chr12:48655088 A/G cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs2404602 0.622 rs4886506 chr15:77207277 G/T cg23625390 chr15:77176239 SCAPER 0.36 4.47 0.37 1.72e-5 Blood metabolite levels; TGCT cis rs7914558 0.899 rs7913682 chr10:104684392 T/A cg04362960 chr10:104952993 NT5C2 0.61 5.41 0.44 3.14e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9790314 0.502 rs2404342 chr3:161092562 C/T cg03342759 chr3:160939853 NMD3 -0.52 -5.38 -0.44 3.56e-7 Morning vs. evening chronotype; TGCT cis rs67478160 0.619 rs12897150 chr14:104319530 A/T cg26031613 chr14:104095156 KLC1 -0.68 -6.98 -0.53 1.61e-10 Schizophrenia; TGCT cis rs7523273 0.597 rs4844390 chr1:207934849 A/G cg22525895 chr1:207977042 MIR29B2 -0.46 -6.64 -0.51 8.7e-10 Schizophrenia; TGCT cis rs916888 0.821 rs199525 chr17:44847834 T/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.74 5.21 0.42 7.56e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT trans rs853410 0.516 rs1886334 chr6:4003364 T/C cg13911294 chr9:88951310 ZCCHC6 -0.67 -6.96 -0.53 1.75e-10 Night sleep phenotypes; TGCT cis rs2720460 0.502 rs223374 chr4:103758301 T/C cg16532752 chr4:104119610 CENPE -0.61 -5.43 -0.44 2.85e-7 Testicular germ cell tumor; TGCT cis rs9467711 1.000 rs9467708 chr6:26327956 T/C cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs1534166 0.647 rs1464937 chr3:133536655 C/G cg08048268 chr3:133502702 NA 0.42 5.15 0.42 9.87e-7 Alcohol consumption (transferrin glycosylation); TGCT cis rs7617773 0.817 rs34225441 chr3:48308891 T/A cg11946769 chr3:48343235 NME6 0.76 6.64 0.51 8.76e-10 Coronary artery disease; TGCT cis rs9611565 0.592 rs9611613 chr22:41961831 T/C cg03806693 chr22:41940476 POLR3H -1.08 -11.36 -0.71 6.34e-21 Vitiligo; TGCT cis rs3096299 0.933 rs2965823 chr16:89454924 G/A cg02187348 chr16:89574699 SPG7 0.46 4.45 0.37 1.88e-5 Multiple myeloma (IgH translocation); TGCT cis rs116095464 0.558 rs62344345 chr5:257420 C/T cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs12908161 1.000 rs62019464 chr15:85294469 T/A cg17173187 chr15:85201210 NMB 0.56 6.32 0.49 4.2e-9 Schizophrenia; TGCT cis rs4733781 0.933 rs1118887 chr8:131202021 A/T cg16277922 chr8:131349729 ASAP1 0.43 5.4 0.44 3.23e-7 Tuberculosis; TGCT cis rs6840360 1.000 rs3749562 chr4:152596540 T/C cg17479576 chr4:152424074 FAM160A1 -0.5 -5.26 -0.43 6.16e-7 Intelligence (multi-trait analysis); TGCT cis rs7542091 0.669 rs7540534 chr1:210044824 A/T cg23283495 chr1:209979779 IRF6 0.55 5.47 0.44 2.34e-7 Monobrow; TGCT trans rs3107575 0.572 rs73169365 chr3:165319778 T/C cg03961853 chr1:230384989 GALNT2 0.64 6.9 0.53 2.41e-10 Morning vs. evening chronotype; TGCT cis rs2832191 0.740 rs2012645 chr21:30445961 G/A cg08807101 chr21:30365312 RNF160 0.65 6.14 0.48 1.03e-8 Dental caries; TGCT cis rs1577917 1.000 rs68171315 chr6:86707400 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs1215050 0.740 rs6855827 chr4:99065706 G/A cg05340658 chr4:99064831 C4orf37 0.44 5.3 0.43 5.03e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs476633 0.708 rs3986303 chr15:41443179 A/G cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.77 -0.62 1.13e-14 Glomerular filtration rate (creatinine); TGCT cis rs17741873 0.830 rs11000801 chr10:75647491 A/C cg07699608 chr10:75541558 CHCHD1 0.66 5.06 0.41 1.49e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs910316 0.967 rs12890371 chr14:75593839 T/C cg08847533 chr14:75593920 NEK9 0.96 10.86 0.7 1.05e-19 Height; TGCT cis rs7552404 1.000 rs6593585 chr1:76140273 G/A cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs7819412 0.745 rs28464654 chr8:11080665 T/A cg06636001 chr8:8085503 FLJ10661 -0.77 -6.86 -0.52 2.93e-10 Triglycerides; TGCT cis rs9583531 0.843 rs7999702 chr13:111382264 A/C cg24331049 chr13:111365604 ING1 -0.75 -5.43 -0.44 2.89e-7 Coronary artery disease; TGCT cis rs3796352 1.000 rs33999310 chr3:52883332 G/A cg15956490 chr3:53032818 SFMBT1 0.57 5.25 0.43 6.25e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7917772 0.636 rs4919674 chr10:104522226 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.56 -4.59 -0.38 1.07e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7662987 0.517 rs2924580 chr4:100032168 C/G cg13256891 chr4:100009986 ADH5 0.52 4.58 0.38 1.12e-5 Smoking initiation; TGCT trans rs2727020 0.521 rs7101761 chr11:49598178 G/A cg11707556 chr5:10655725 ANKRD33B -0.4 -7.69 -0.57 3.92e-12 Coronary artery disease; TGCT cis rs739401 0.527 rs418832 chr11:3072236 C/T cg25174290 chr11:3078921 CARS 0.51 4.96 0.41 2.23e-6 Longevity; TGCT cis rs1941023 0.584 rs2197236 chr11:60168859 T/C cg08716584 chr11:60157161 MS4A7 -0.31 -4.69 -0.39 7.18e-6 Congenital heart disease (maternal effect); TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT trans rs7618501 0.602 rs2240326 chr3:50128386 G/A cg21659725 chr3:3221576 CRBN -0.74 -8.78 -0.62 1.08e-14 Intelligence (multi-trait analysis); TGCT cis rs875971 1.000 rs709595 chr7:65817333 G/C cg18876405 chr7:65276391 NA 0.32 4.93 0.4 2.61e-6 Aortic root size; TGCT trans rs7819412 0.806 rs17723229 chr8:10930069 A/C cg15556689 chr8:8085844 FLJ10661 -0.84 -8.17 -0.59 2.99e-13 Triglycerides; TGCT cis rs17125944 0.505 rs76219229 chr14:53178346 G/A cg00686598 chr14:53173677 PSMC6 1.2 6.43 0.5 2.51e-9 Alzheimer's disease (late onset); TGCT cis rs2594989 0.790 rs2443716 chr3:11523670 A/G cg00170343 chr3:11313890 ATG7 0.68 5.46 0.44 2.49e-7 Circulating chemerin levels; TGCT cis rs4820539 1.000 rs5759598 chr22:23480962 T/G cg14186256 chr22:23484241 RTDR1 0.99 12.69 0.75 3.59e-24 Bone mineral density; TGCT cis rs281408 0.559 rs281386 chr19:49217305 A/G cg13540341 chr19:49222985 MAMSTR 0.46 6.76 0.52 4.92e-10 Urinary metabolites (H-NMR features); TGCT cis rs2439831 1.000 rs2467739 chr15:43740196 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs73198271 0.960 rs17154702 chr8:8609880 C/T cg06636001 chr8:8085503 FLJ10661 -0.63 -4.59 -0.38 1.08e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9611565 0.729 rs169362 chr22:41827589 G/C cg06481639 chr22:41940642 POLR3H 0.59 5.12 0.42 1.12e-6 Vitiligo; TGCT cis rs16866061 1.000 rs10933068 chr2:225418360 G/A cg12698349 chr2:225449008 CUL3 1.0 10.02 0.67 1.14e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs3784262 1.000 rs12908953 chr15:58277812 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.7 -0.57 3.76e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9911578 1.000 rs8071916 chr17:56660279 A/G cg12560992 chr17:57184187 TRIM37 0.75 9.11 0.63 1.79e-15 Intelligence (multi-trait analysis); TGCT cis rs595982 0.559 rs73061632 chr19:49361663 G/A cg15549821 chr19:49342101 PLEKHA4 -0.71 -9.68 -0.66 7.61e-17 Red cell distribution width; TGCT cis rs3821902 0.646 rs17344716 chr3:64019744 T/A cg22134162 chr3:63841271 THOC7 -0.33 -4.89 -0.4 3.1e-6 Breast cancer; TGCT cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg03806693 chr22:41940476 POLR3H -0.96 -9.51 -0.65 1.96e-16 Vitiligo; TGCT cis rs950169 0.544 rs2036949 chr15:85163605 T/C cg17173187 chr15:85201210 NMB 0.58 6.62 0.51 9.59e-10 Schizophrenia; TGCT cis rs832540 0.593 rs96844 chr5:56196604 G/A cg12311346 chr5:56204834 C5orf35 -0.5 -4.79 -0.4 4.68e-6 Coronary artery disease; TGCT cis rs6667605 0.527 rs6673993 chr1:2552071 T/C cg18854424 chr1:2615690 NA 0.5 5.95 0.47 2.54e-8 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs9916302 0.660 rs4795379 chr17:37674683 T/G cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs4237845 0.780 rs3751331 chr12:58290278 G/A cg02175503 chr12:58329896 NA 0.52 4.86 0.4 3.52e-6 Intelligence (multi-trait analysis); TGCT cis rs8056742 0.642 rs12934305 chr16:85027718 C/G cg00229868 chr16:85520891 NA -0.37 -4.64 -0.38 8.75e-6 Amyotrophic lateral sclerosis; TGCT cis rs546131 0.928 rs516228 chr11:34838823 C/T cg11058730 chr11:34937778 PDHX;APIP 0.51 4.54 0.38 1.34e-5 Lung disease severity in cystic fibrosis; TGCT cis rs17376456 0.597 rs10866760 chr5:93338335 G/A cg21475434 chr5:93447410 FAM172A -0.64 -5.91 -0.47 3.04e-8 Diabetic retinopathy; TGCT cis rs977747 1.000 rs7664 chr1:47682017 T/G cg03885399 chr1:47691550 TAL1 -0.39 -4.69 -0.39 7.14e-6 Body mass index; TGCT cis rs4906332 1.000 rs78316803 chr14:103942863 A/G cg26031613 chr14:104095156 KLC1 -0.52 -4.72 -0.39 6.31e-6 Coronary artery disease; TGCT cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.31 0.43 4.88e-7 Menopause (age at onset); TGCT cis rs13242816 1.000 rs12668226 chr7:116187690 A/C cg02799643 chr7:116139180 CAV2 -0.45 -5.55 -0.45 1.66e-7 P wave duration; TGCT cis rs6733011 0.578 rs1581251 chr2:99500867 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.67 -0.39 7.81e-6 Bipolar disorder; TGCT cis rs208520 0.690 rs12194057 chr6:66745616 A/G cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs732765 0.734 rs28470774 chr14:75186907 C/T cg06637938 chr14:75390232 RPS6KL1 -0.55 -4.48 -0.37 1.71e-5 Non-small cell lung cancer; TGCT cis rs2439831 0.850 rs3816792 chr15:44116986 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.89 -6.27 -0.49 5.48e-9 Lung cancer in ever smokers; TGCT cis rs7772486 0.597 rs6570732 chr6:146245151 G/A cg05347473 chr6:146136440 FBXO30 -0.64 -6.06 -0.48 1.48e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs9837602 0.529 rs793494 chr3:99508768 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.56 6.42 0.5 2.56e-9 Breast cancer; TGCT cis rs793571 0.522 rs11071398 chr15:59120077 A/G cg05156742 chr15:59063176 FAM63B 0.54 5.07 0.41 1.38e-6 Schizophrenia; TGCT cis rs7017914 0.870 rs3098883 chr8:71943567 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.93 -0.4 2.62e-6 Bone mineral density; TGCT trans rs208520 0.754 rs12204635 chr6:66740779 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs10791323 0.628 rs2851118 chr11:133705995 A/C cg03690763 chr11:133734501 NA -0.35 -5.39 -0.44 3.39e-7 Childhood ear infection; TGCT cis rs7937682 0.632 rs10891294 chr11:111699224 C/T cg09085632 chr11:111637200 PPP2R1B 0.81 7.03 0.53 1.23e-10 Primary sclerosing cholangitis; TGCT cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg04025307 chr7:1156635 C7orf50 0.24 5.46 0.44 2.51e-7 Longevity;Endometriosis; TGCT cis rs919433 0.680 rs1563340 chr2:198414713 A/T cg00792783 chr2:198669748 PLCL1 0.5 4.55 0.38 1.28e-5 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs6921919 0.583 rs2041230 chr6:28365515 A/G cg18815343 chr6:28367644 ZSCAN12 -0.53 -5.06 -0.41 1.47e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9894429 0.505 rs35570626 chr17:79611084 A/G cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs2677744 1.000 rs1550636 chr15:91477461 A/G cg23684204 chr15:91497937 RCCD1 0.35 5.14 0.42 1.06e-6 Attention deficit hyperactivity disorder; TGCT cis rs732765 0.734 rs11844127 chr14:75139936 C/G cg06637938 chr14:75390232 RPS6KL1 -0.57 -4.94 -0.41 2.43e-6 Non-small cell lung cancer; TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg14851468 chr5:179071604 C5orf60 0.27 5.58 0.45 1.42e-7 Lung cancer; TGCT cis rs7336332 0.598 rs76249173 chr13:28010445 A/G cg22138327 chr13:27999177 GTF3A 0.8 5.97 0.47 2.35e-8 Weight; TGCT cis rs6500602 0.793 rs4785964 chr16:4484613 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.39 5.85 0.46 4.14e-8 Schizophrenia; TGCT cis rs796364 1.000 rs11680723 chr2:200810957 C/G cg17644776 chr2:200775616 C2orf69 -0.31 -4.83 -0.4 3.99e-6 Schizophrenia; TGCT cis rs13064411 0.735 rs722392 chr3:113228294 A/G cg18753928 chr3:113234510 CCDC52 -0.7 -5.68 -0.45 9.16e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs3849570 1.000 rs78242412 chr3:81747219 A/G cg07356753 chr3:81810745 GBE1 -0.82 -7.89 -0.58 1.37e-12 Waist circumference;Body mass index; TGCT cis rs6671200 1.000 rs35179427 chr1:95670888 G/A cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs4383453 0.539 rs4678016 chr3:123101981 C/T cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs7523273 0.597 rs11118580 chr1:207959070 T/C cg22525895 chr1:207977042 MIR29B2 -0.46 -6.64 -0.51 9e-10 Schizophrenia; TGCT cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs6988636 1.000 rs13259806 chr8:124190103 A/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9467773 1.000 rs6925895 chr6:26572165 G/T cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs10876993 0.928 rs2928053 chr12:58063475 T/C cg15848620 chr12:58087721 OS9 -0.73 -6.02 -0.48 1.8e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs17376456 1.000 rs61132622 chr5:93539684 G/A cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.96e-12 Diabetic retinopathy; TGCT trans rs57221529 0.766 rs56350081 chr5:583198 G/A cg25482853 chr8:67687455 SGK3 1.2 10.12 0.67 6.42e-18 Lung disease severity in cystic fibrosis; TGCT cis rs2730260 0.537 rs73169238 chr7:158883818 G/A cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT trans rs9388451 0.839 rs3799709 chr6:126078361 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.58 -0.61 3.3e-14 Brugada syndrome; TGCT cis rs4713118 0.515 rs9368549 chr6:28050047 T/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Parkinson's disease; TGCT cis rs832540 0.931 rs2591960 chr5:56238811 A/T cg12311346 chr5:56204834 C5orf35 0.53 5.23 0.43 6.91e-7 Coronary artery disease; TGCT cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12681287 0.517 rs34367154 chr8:87508749 A/T cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs4242434 0.819 rs2306518 chr8:22470308 A/G cg03733263 chr8:22462867 KIAA1967 1.09 17.22 0.84 1.13e-34 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7246657 0.722 rs2909105 chr19:38167906 A/G cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT cis rs926938 0.618 rs516985 chr1:115495011 G/A cg12756093 chr1:115239321 AMPD1 0.39 5.78 0.46 5.69e-8 Autism; TGCT cis rs360798 0.512 rs34104251 chr2:62995183 A/G cg17519650 chr2:63277830 OTX1 -0.6 -5.32 -0.43 4.76e-7 Coronary artery disease; TGCT cis rs7336332 0.598 rs74563672 chr13:28010660 A/G cg22138327 chr13:27999177 GTF3A 0.8 5.97 0.47 2.35e-8 Weight; TGCT cis rs12681288 0.862 rs34510005 chr8:1018943 T/C cg08872321 chr8:1308229 NA -0.26 -4.65 -0.39 8.45e-6 Schizophrenia; TGCT cis rs601339 1.000 rs635400 chr12:123171089 A/G cg11919336 chr12:123188078 GPR109A 0.66 7.7 0.57 3.69e-12 Adiponectin levels; TGCT cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg13683864 chr3:40499215 RPL14 -1.19 -13.31 -0.77 1.2e-25 Renal cell carcinoma; TGCT cis rs9486719 0.843 rs1009597 chr6:96843540 A/T cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs1062177 0.826 rs2915879 chr5:151147442 A/G cg12924095 chr5:151150029 G3BP1 0.34 5.0 0.41 1.9e-6 Preschool internalizing problems; TGCT cis rs4819052 0.851 rs2255774 chr21:46683851 A/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 7.09 0.54 9.14e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7178572 0.568 rs1446312 chr15:77412189 G/C cg15453836 chr15:77711506 NA -0.42 -4.68 -0.39 7.31e-6 Type 2 diabetes; TGCT cis rs9952991 0.622 rs8091566 chr18:12826385 G/A cg23598886 chr18:12777645 NA 0.54 4.76 0.39 5.29e-6 Inflammatory skin disease; TGCT cis rs7267979 1.000 rs4815406 chr20:25341316 C/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8016982 0.698 rs8011097 chr14:81702736 T/C cg01989461 chr14:81687754 GTF2A1 0.77 7.18 0.54 5.7e-11 Schizophrenia; TGCT cis rs2153535 0.580 rs7753192 chr6:8482637 G/A cg23788917 chr6:8435910 SLC35B3 0.62 5.59 0.45 1.37e-7 Motion sickness; TGCT cis rs7829975 0.714 rs12544992 chr8:8661681 C/G cg06636001 chr8:8085503 FLJ10661 0.67 5.75 0.46 6.61e-8 Mood instability; TGCT cis rs6669384 0.774 rs4844623 chr1:208035434 T/A cg22525895 chr1:207977042 MIR29B2 -0.39 -5.53 -0.44 1.82e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs2075371 0.501 rs1643043 chr7:134013902 C/T cg11752832 chr7:134001865 SLC35B4 0.58 4.78 0.39 4.95e-6 Mean platelet volume; TGCT cis rs9814567 1.000 rs6800862 chr3:134228628 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -9.27 -0.64 7.51e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7614311 0.731 rs3774721 chr3:63954649 A/G cg22134162 chr3:63841271 THOC7 -0.45 -5.73 -0.46 7.3e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs3540 0.576 rs12907587 chr15:91045851 G/C cg22089800 chr15:90895588 ZNF774 -0.75 -7.59 -0.56 6.74e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs1451375 0.959 rs6962356 chr7:50621941 T/C cg18232548 chr7:50535776 DDC 0.44 6.76 0.52 4.7e-10 Malaria; TGCT cis rs3087591 0.922 rs12939969 chr17:29463577 A/G cg24425628 chr17:29625626 OMG;NF1 0.49 7.61 0.56 6.09e-12 Hip circumference; TGCT cis rs678347 0.961 rs601897 chr8:102469182 C/T cg26560785 chr8:103251167 RRM2B 0.55 4.46 0.37 1.83e-5 Rheumatoid arthritis; TGCT cis rs6089584 1.000 rs6089580 chr20:60558976 G/A cg06108461 chr20:60628389 TAF4 -0.57 -8.01 -0.58 7.25e-13 Body mass index; TGCT cis rs17767294 0.708 rs72847342 chr6:27789270 A/G cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs3733585 0.673 rs6840802 chr4:9965633 C/G cg00071950 chr4:10020882 SLC2A9 0.54 6.38 0.5 3.14e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg08280861 chr8:58055591 NA 0.36 4.98 0.41 2.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs7822232 0.908 rs6558297 chr8:145143934 C/T cg06495924 chr8:145149574 CYC1 -1.04 -4.49 -0.37 1.6e-5 Blood metabolite levels; TGCT cis rs28595532 0.844 rs115411027 chr4:119490685 T/C cg21605333 chr4:119757512 SEC24D 1.33 8.01 0.58 7.07e-13 Cannabis dependence symptom count; TGCT cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg03517284 chr6:25882590 NA -0.66 -5.95 -0.47 2.55e-8 Intelligence (multi-trait analysis); TGCT cis rs4790312 0.513 rs9912609 chr17:1967620 A/G cg24156229 chr17:1948635 NA -0.34 -5.33 -0.43 4.49e-7 Left atrial antero-posterior diameter; TGCT cis rs9443645 0.901 rs2174742 chr6:79610101 G/T cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs6690583 0.562 rs6688354 chr1:85520854 A/G cg20280350 chr1:85513789 MCOLN3 -0.82 -5.27 -0.43 5.92e-7 Serum sulfate level; TGCT cis rs4727027 0.901 rs4727018 chr7:148822247 G/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs11577318 0.812 rs3795683 chr1:26632831 C/A cg04990556 chr1:26633338 UBXN11 -0.63 -5.77 -0.46 6.01e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs10479542 0.896 rs10078712 chr5:178978805 C/T cg19723775 chr5:179050963 HNRNPH1 -0.54 -5.34 -0.43 4.24e-7 Lung cancer; TGCT cis rs11785400 1.000 rs10099892 chr8:143734608 C/T cg24634471 chr8:143751801 JRK 0.56 6.12 0.48 1.12e-8 Schizophrenia; TGCT cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg17554472 chr22:41940697 POLR3H -0.42 -4.56 -0.38 1.19e-5 Vitiligo; TGCT cis rs10927875 0.864 rs1976402 chr1:16143779 G/A cg14742211 chr1:16348397 CLCNKA -0.2 -4.52 -0.38 1.44e-5 Dilated cardiomyopathy; TGCT cis rs7954584 0.567 rs1169071 chr12:122390084 G/T cg21171335 chr12:122356390 WDR66 0.71 7.5 0.56 1.06e-11 Mean corpuscular volume; TGCT cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.52 -0.38 1.43e-5 Electroencephalogram traits; TGCT trans rs877282 0.786 rs10904558 chr10:797509 C/T cg22713356 chr15:30763199 NA 1.16 10.39 0.68 1.44e-18 Uric acid levels; TGCT cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg07424592 chr7:64974309 NA 1.26 7.79 0.57 2.25e-12 Diabetic kidney disease; TGCT cis rs11190604 1.000 rs10883501 chr10:102238326 A/G cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9303401 0.659 rs34818467 chr17:56643109 C/T cg25039879 chr17:56429692 SUPT4H1 -0.52 -4.68 -0.39 7.47e-6 Cognitive test performance; TGCT cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg09323728 chr8:95962352 TP53INP1 -0.55 -7.07 -0.54 9.72e-11 Type 2 diabetes; TGCT cis rs13082711 0.522 rs6551192 chr3:27343376 C/T cg02860705 chr3:27208620 NA 0.32 5.24 0.43 6.54e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT trans rs1973993 0.507 rs2759670 chr1:97002864 A/G cg10631902 chr5:14652156 NA 0.37 9.46 0.65 2.54e-16 Weight; TGCT cis rs9796 0.870 rs2927061 chr15:41302219 A/G cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.3 -0.43 5.07e-7 Menopause (age at onset); TGCT cis rs9929218 0.906 rs9932679 chr16:68751904 A/G cg01251360 chr16:68772225 CDH1 0.3 5.0 0.41 1.88e-6 Colorectal cancer; TGCT cis rs1008375 1.000 rs2315560 chr4:17677305 C/G cg16339924 chr4:17578868 LAP3 0.53 4.62 0.38 9.53e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs459571 0.883 rs2520096 chr9:136919416 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.8 -8.66 -0.61 2.13e-14 Platelet distribution width; TGCT cis rs13188771 0.578 rs67960514 chr5:100905390 G/A cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7727544 0.716 rs3844312 chr5:131582356 C/T cg22598563 chr5:131563921 P4HA2 -0.29 -4.66 -0.39 7.88e-6 Blood metabolite levels; TGCT cis rs909674 0.524 rs5750821 chr22:39825492 A/T cg05872129 chr22:39784769 NA -0.98 -10.82 -0.7 1.27e-19 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4699052 0.625 rs1516740 chr4:104295787 C/T cg16532752 chr4:104119610 CENPE 0.49 4.74 0.39 5.82e-6 Testicular germ cell tumor; TGCT cis rs1790761 0.501 rs4930210 chr11:67404726 G/T cg00290607 chr11:67383545 NA -0.32 -5.21 -0.42 7.5e-7 Mean corpuscular volume; TGCT cis rs3091242 0.933 rs9645452 chr1:25668326 C/T cg23205692 chr1:25664452 TMEM50A -0.52 -5.38 -0.43 3.61e-7 Erythrocyte sedimentation rate; TGCT cis rs2455799 0.613 rs7620787 chr3:15882826 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.8 -0.4 4.53e-6 Mean platelet volume; TGCT trans rs11662586 0.517 rs11663082 chr18:77713494 C/T cg05926928 chr17:57297772 GDPD1 0.76 7.2 0.54 5.06e-11 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs1322512 1.000 rs1727054 chr6:152947742 A/G cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs7607369 0.526 rs4674322 chr2:219513782 C/T cg02176678 chr2:219576539 TTLL4 0.51 5.94 0.47 2.7e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs3091242 0.806 rs35189848 chr1:25788422 A/G cg23205692 chr1:25664452 TMEM50A -0.49 -5.1 -0.42 1.26e-6 Erythrocyte sedimentation rate; TGCT trans rs1814175 0.935 rs7482690 chr11:49648814 C/T cg03929089 chr4:120376271 NA -0.65 -7.45 -0.56 1.35e-11 Height; TGCT cis rs6740322 0.895 rs10196095 chr2:43571885 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.18 -0.49 8.32e-9 Coronary artery disease; TGCT cis rs3806843 0.778 rs2531346 chr5:140126139 T/G cg19875535 chr5:140030758 IK -0.34 -5.68 -0.45 9.12e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs11785400 0.642 rs4256574 chr8:143725705 C/T cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs7681423 1.000 rs2066865 chr4:155525276 G/A cg20735720 chr4:155535218 FGG -0.46 -6.8 -0.52 4e-10 Fibrinogen; TGCT cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg10047753 chr17:41438598 NA 0.97 9.94 0.67 1.73e-17 Menopause (age at onset); TGCT cis rs10751667 0.643 rs6597969 chr11:928843 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs13064411 0.696 rs13066742 chr3:113208423 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.64 -0.45 1.08e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs57221529 0.766 rs17497684 chr5:558307 T/C cg09021430 chr5:549028 NA -0.4 -5.46 -0.44 2.44e-7 Lung disease severity in cystic fibrosis; TGCT cis rs2354432 0.556 rs885305 chr1:146786080 G/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg27286337 chr10:134555280 INPP5A 0.39 4.73 0.39 6.02e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs68170813 0.559 rs17349904 chr7:106897237 A/C cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs11031096 0.676 rs7120125 chr11:3941264 C/T cg18678763 chr11:4115507 RRM1 0.39 5.25 0.43 6.38e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2549003 1.000 rs7734334 chr5:131815004 C/A cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs2242194 0.816 rs11264296 chr1:154994750 T/C cg16680214 chr1:154839983 KCNN3 -0.31 -5.81 -0.46 4.84e-8 Schizophrenia; TGCT cis rs17253792 0.822 rs58569951 chr14:56152245 T/C cg01858014 chr14:56050164 KTN1 -0.33 -4.54 -0.38 1.33e-5 Putamen volume; TGCT cis rs807669 0.548 rs762522 chr22:19180575 C/T cg02655711 chr22:19163373 SLC25A1 0.33 6.83 0.52 3.41e-10 Metabolite levels; TGCT cis rs9303401 0.614 rs68100606 chr17:56500898 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.68 6.75 0.52 5.15e-10 Cognitive test performance; TGCT cis rs13191362 0.935 rs116735807 chr6:163010615 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10791097 0.694 rs10894273 chr11:130742155 G/T cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs45430 0.665 rs431563 chr21:42740949 C/T cg22778903 chr21:42741698 MX2 0.3 4.86 0.4 3.43e-6 Melanoma; TGCT cis rs2070488 0.775 rs1132064 chr3:38566519 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.89 -0.53 2.46e-10 Electrocardiographic conduction measures; TGCT cis rs617219 0.710 rs2607142 chr5:78557948 T/C cg09550809 chr5:78407562 BHMT 0.37 5.24 0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs208520 0.690 rs207740 chr6:66764132 T/G cg07460842 chr6:66804631 NA 0.96 10.32 0.68 2.1e-18 Exhaled nitric oxide output; TGCT cis rs12188164 1.000 rs72717410 chr5:428785 A/T cg22025206 chr5:502436 SLC9A3 -0.25 -4.47 -0.37 1.71e-5 Cystic fibrosis severity; TGCT cis rs7980687 0.574 rs10744149 chr12:123708490 T/A cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Height;Educational attainment;Head circumference (infant); TGCT cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg09177884 chr7:1199841 ZFAND2A -0.52 -4.99 -0.41 2.02e-6 Longevity;Endometriosis; TGCT cis rs11169225 0.906 rs399023 chr12:50338952 A/C cg04450003 chr12:50355995 AQP5 0.29 4.73 0.39 5.89e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs56104184 0.775 rs55981795 chr19:49401952 A/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2535633 0.661 rs4515041 chr3:52996032 T/A cg11645453 chr3:52864694 ITIH4 -0.28 -5.13 -0.42 1.1e-6 Body mass index; TGCT cis rs4509693 1.000 rs4244340 chr10:102499268 G/C cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs916888 0.610 rs199452 chr17:44801340 C/T cg17911788 chr17:44343683 NA -0.48 -5.66 -0.45 9.83e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg08439880 chr3:133502540 NA -0.27 -4.87 -0.4 3.28e-6 Iron status biomarkers; TGCT cis rs10114408 0.959 rs4354373 chr9:96650369 A/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1887596 0.663 rs1298079 chr13:27246261 A/G cg01312412 chr13:27282625 NA 0.28 5.01 0.41 1.79e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs3849570 1.000 rs2290081 chr3:81810725 C/T cg07356753 chr3:81810745 GBE1 -0.84 -7.89 -0.58 1.35e-12 Waist circumference;Body mass index; TGCT cis rs7726839 0.507 rs72703100 chr5:614291 C/T cg20362242 chr5:692897 TPPP 0.52 4.48 0.37 1.68e-5 Obesity-related traits; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg04234412 chr22:24373322 LOC391322 0.92 10.83 0.7 1.2e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg09904177 chr6:26538194 HMGN4 0.64 5.95 0.47 2.56e-8 Intelligence (multi-trait analysis); TGCT cis rs66573146 1.000 rs9942188 chr4:6984181 C/T cg05069807 chr4:6945702 TBC1D14 0.35 4.94 0.41 2.51e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9303542 0.625 rs8073963 chr17:46609918 G/A cg25032089 chr17:46643351 HOXB3 -0.53 -5.54 -0.45 1.76e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs11874712 1.000 rs8088881 chr18:43664970 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs12477438 0.834 rs1563107 chr2:99701276 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.88 9.09 0.63 1.97e-15 Chronic sinus infection; TGCT cis rs3806843 1.000 rs3733710 chr5:140167463 C/T cg19875535 chr5:140030758 IK 0.37 6.33 0.49 4.17e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7819412 0.740 rs28633434 chr8:11053922 G/A cg21775007 chr8:11205619 TDH -0.48 -4.58 -0.38 1.1e-5 Triglycerides; TGCT cis rs6964587 0.732 rs12539523 chr7:91710836 G/A cg17063962 chr7:91808500 NA 0.88 9.54 0.65 1.69e-16 Breast cancer; TGCT cis rs425277 0.628 rs3107145 chr1:2047547 G/A cg24578937 chr1:2090814 PRKCZ -0.26 -6.1 -0.48 1.23e-8 Height; TGCT cis rs6547741 1.000 rs1528404 chr2:27846603 C/T cg27432699 chr2:27873401 GPN1 -0.18 -4.56 -0.38 1.2e-5 Oral cavity cancer; TGCT cis rs72945132 0.882 rs7932431 chr11:70166059 A/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs732765 0.644 rs2268613 chr14:75408500 G/A cg06637938 chr14:75390232 RPS6KL1 0.65 5.36 0.43 3.85e-7 Non-small cell lung cancer; TGCT cis rs9318086 0.624 rs9510909 chr13:24436760 C/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.79 8.37 0.6 1.05e-13 Myopia (pathological); TGCT cis rs875971 0.825 rs28480509 chr7:66099224 A/G cg11764359 chr7:65958608 NA -0.55 -4.98 -0.41 2.1e-6 Aortic root size; TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg11003573 chr3:44754125 ZNF502 -0.4 -4.53 -0.38 1.35e-5 Depressive symptoms; TGCT cis rs244731 0.959 rs7721671 chr5:176630984 A/G cg06060754 chr5:176797920 RGS14 -0.44 -6.2 -0.49 7.79e-9 Urate levels in lean individuals; TGCT cis rs79387448 0.701 rs10515921 chr2:102981018 T/G cg09003973 chr2:102972529 NA 1.47 10.36 0.68 1.69e-18 Gut microbiota (bacterial taxa); TGCT cis rs514406 0.505 rs448788 chr1:53161620 A/G cg01802117 chr1:53393560 SCP2 0.43 4.89 0.4 3.08e-6 Monocyte count; TGCT cis rs7666738 0.606 rs4577589 chr4:99087858 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2050392 0.517 rs687036 chr10:30761249 G/A cg13289132 chr10:30722225 MAP3K8 -0.39 -4.8 -0.4 4.53e-6 Inflammatory bowel disease; TGCT cis rs6940638 0.956 rs13207365 chr6:27030980 T/C cg16898833 chr6:26189333 HIST1H4D 0.71 5.34 0.43 4.2e-7 Intelligence (multi-trait analysis); TGCT cis rs66561647 1.000 rs66561647 chr8:128971861 C/T cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.46 0.37 1.79e-5 Hemoglobin concentration; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg10819733 chr22:24237672 NA -0.29 -4.9 -0.4 2.99e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836974 0.644 rs11088472 chr21:40699376 A/C cg17971929 chr21:40555470 PSMG1 -0.68 -5.95 -0.47 2.6e-8 Cognitive function; TGCT cis rs797680 0.856 rs4847408 chr1:93791437 C/G cg17826107 chr1:92977322 EVI5 0.22 5.05 0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs3820068 0.705 rs59502343 chr1:15872617 T/C cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT trans rs1496653 0.602 rs71322200 chr3:23614390 C/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs4455778 0.658 rs111468777 chr7:49117642 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs881375 1.000 rs10760118 chr9:123641616 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.57 0.38 1.18e-5 Rheumatoid arthritis; TGCT trans rs10506458 1.000 rs73128779 chr12:63441852 T/G cg22491629 chr6:157744540 C6orf35 -0.96 -8.34 -0.6 1.21e-13 Hemostatic factors and hematological phenotypes; TGCT trans rs11671005 0.610 rs4756 chr19:59074653 T/C cg22037779 chr5:139682734 PFDN1 -0.85 -6.91 -0.53 2.25e-10 Mean platelet volume; TGCT cis rs17767294 0.614 rs116152083 chr6:28541959 A/G cg08851530 chr6:28072375 NA 1.52 6.87 0.52 2.83e-10 Parkinson's disease; TGCT cis rs9383153 1.000 rs2237223 chr6:16329741 G/A cg10975897 chr6:15504844 JARID2 0.8 4.45 0.37 1.88e-5 Gambling; TGCT cis rs2721195 0.626 rs59464125 chr8:145857786 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 -0.89 -9.47 -0.65 2.42e-16 Age at first birth; TGCT cis rs6671200 0.607 rs3767313 chr1:95712797 G/A cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs155076 0.711 rs4770131 chr13:21897468 A/G cg14456004 chr13:21872349 NA 1.29 11.07 0.71 3.11e-20 White matter hyperintensity burden; TGCT cis rs916888 0.610 rs199536 chr17:44820425 T/C cg17911788 chr17:44343683 NA 0.48 5.67 0.45 9.45e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17433780 0.612 rs7911 chr1:89518120 A/G cg09516651 chr1:89888402 LOC400759 0.23 4.63 0.38 9.11e-6 Carotid intima media thickness; TGCT cis rs35306767 0.953 rs11253509 chr10:964306 C/T cg26597838 chr10:835615 NA 0.63 9.1 0.63 1.93e-15 Eosinophil percentage of granulocytes; TGCT cis rs4851266 1.000 rs2871344 chr2:100839430 A/G cg07810366 chr2:100720526 AFF3 -0.37 -5.33 -0.43 4.39e-7 Educational attainment; TGCT cis rs10514758 0.744 rs4831110 chr3:114939276 A/G cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs7091068 0.518 rs726817 chr10:95459817 C/T cg20715218 chr10:95462985 C10orf4 0.52 5.51 0.44 1.99e-7 Urinary tract infection frequency; TGCT cis rs9902453 0.753 rs3097118 chr17:27978466 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.48 0.61 5.74e-14 Coffee consumption (cups per day); TGCT cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs12042938 0.935 rs823167 chr1:231767230 G/A cg04892437 chr1:231737901 TSNAX-DISC1 0.44 4.52 0.38 1.4e-5 Neuranatomic and neurocognitive phenotypes; TGCT cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT trans rs1814175 0.645 rs28549248 chr11:50042740 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs12188164 1.000 rs34847072 chr5:437862 G/C cg26850624 chr5:429559 AHRR -0.2 -4.73 -0.39 6.01e-6 Cystic fibrosis severity; TGCT cis rs2239547 0.603 rs34230854 chr3:53078590 C/A cg11645453 chr3:52864694 ITIH4 0.29 4.62 0.38 9.33e-6 Schizophrenia; TGCT cis rs12681288 0.748 rs2701935 chr8:1028618 T/A cg04851639 chr8:1020857 NA -0.34 -6.11 -0.48 1.18e-8 Schizophrenia; TGCT cis rs4950928 0.823 rs2494277 chr1:203168092 A/G cg17014757 chr1:203156097 CHI3L1 -0.4 -4.97 -0.41 2.15e-6 YKL-40 levels; TGCT cis rs938554 0.571 rs12509955 chr4:10024303 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -4.92 -0.4 2.67e-6 Blood metabolite levels; TGCT cis rs7772486 0.875 rs2207785 chr6:146332784 T/G cg23711669 chr6:146136114 FBXO30 0.86 9.55 0.65 1.57e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs524281 0.861 rs918299 chr11:65927607 C/T cg00563793 chr11:65837595 PACS1 0.56 4.74 0.39 5.69e-6 Electroencephalogram traits; TGCT cis rs7226408 0.857 rs8099124 chr18:34593676 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg06753367 chr22:24256600 NA -0.25 -4.73 -0.39 5.98e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9914988 0.943 rs9303621 chr17:27161138 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs736408 0.570 rs11130327 chr3:52793239 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.81 0.46 4.91e-8 Bipolar disorder; TGCT cis rs7617773 0.815 rs7624450 chr3:48350375 A/G cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs9584850 0.834 rs7334078 chr13:99120484 C/T cg15168958 chr13:99100528 FARP1 0.23 4.51 0.38 1.5e-5 Neuroticism; TGCT cis rs736408 0.716 rs2239549 chr3:52823126 C/T cg10802521 chr3:52805072 NEK4 -0.72 -8.93 -0.63 4.86e-15 Bipolar disorder; TGCT cis rs8177253 1.000 rs3811647 chr3:133484029 G/A cg16414030 chr3:133502952 NA -0.61 -9.62 -0.65 1.06e-16 Iron status biomarkers; TGCT cis rs2439831 0.867 rs8039638 chr15:43634405 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg11905131 chr22:24372483 LOC391322 -0.56 -4.44 -0.37 1.93e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2243480 1.000 rs160643 chr7:65558222 C/T cg07424592 chr7:64974309 NA 1.14 7.5 0.56 1.07e-11 Diabetic kidney disease; TGCT cis rs3008870 1.000 rs2985817 chr1:67398607 G/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.97 0.73 2.07e-22 Lymphocyte percentage of white cells; TGCT cis rs611744 0.538 rs2298605 chr8:109272006 T/C cg21045802 chr8:109455806 TTC35 0.82 8.65 0.61 2.19e-14 Dupuytren's disease; TGCT cis rs6088590 0.931 rs6088617 chr20:33408036 G/A cg24642439 chr20:33292090 TP53INP2 0.68 6.09 0.48 1.32e-8 Coronary artery disease; TGCT cis rs2439831 1.000 rs2439831 chr15:43784475 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.76 5.25 0.43 6.46e-7 Lung cancer in ever smokers; TGCT cis rs12681287 0.640 rs8635 chr8:87479810 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs66561647 0.661 rs35851359 chr8:128935626 G/C cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.57 0.38 1.18e-5 Hemoglobin concentration; TGCT cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.23e-9 Blood metabolite levels; TGCT cis rs9549260 0.755 rs59308928 chr13:41245079 C/T cg21288729 chr13:41239152 FOXO1 1.0 10.25 0.68 3.06e-18 Red blood cell count; TGCT cis rs617219 0.684 rs2896766 chr5:78586493 A/G cg23987322 chr5:78407566 BHMT -0.35 -4.7 -0.39 6.68e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2692947 0.644 rs772154 chr2:97021664 G/T cg22654517 chr2:96458247 NA 0.21 4.6 0.38 1.01e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6138458 1.000 rs7269416 chr20:24976196 T/G cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs8030485 0.756 rs1521624 chr15:79412399 C/A cg17916960 chr15:79447300 NA 0.35 4.87 0.4 3.29e-6 Left ventricle wall thickness; TGCT cis rs1362404 0.649 rs34129201 chr16:51956358 G/A cg00216305 chr16:51625890 NA -0.27 -4.52 -0.38 1.41e-5 Gut microbiota (bacterial taxa); TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg06896619 chr17:61851486 DDX42;CCDC47 0.51 4.96 0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs3087591 0.960 rs2905878 chr17:29511199 T/C cg24425628 chr17:29625626 OMG;NF1 0.45 6.95 0.53 1.84e-10 Hip circumference; TGCT cis rs2404618 0.624 rs4457358 chr8:1477213 C/A cg13402656 chr8:1511478 DLGAP2 -0.38 -6.36 -0.5 3.52e-9 Lung cancer; TGCT cis rs12210905 1.000 rs12213361 chr6:27138387 T/C cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT trans rs1814175 0.817 rs1996982 chr11:49972619 G/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs4499344 0.921 rs4805776 chr19:33087759 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.6 -0.51 1.07e-9 Mean platelet volume; TGCT cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs1552244 0.554 rs17050705 chr3:10046398 G/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs7267979 0.565 rs6107059 chr20:25592431 C/A cg03522245 chr20:25566470 NINL -0.45 -4.69 -0.39 6.99e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7336332 0.574 rs9512699 chr13:28029896 G/A cg22138327 chr13:27999177 GTF3A -0.73 -5.85 -0.47 4.11e-8 Weight; TGCT cis rs28595532 0.688 rs116580819 chr4:119767362 T/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs7666738 0.515 rs13131874 chr4:98779183 A/G cg18180107 chr4:99064573 C4orf37 0.54 4.74 0.39 5.8e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9810089 0.903 rs10935185 chr3:136290529 C/G cg12473912 chr3:136751656 NA 0.34 4.83 0.4 3.9e-6 Gestational age at birth (child effect); TGCT cis rs10779751 0.734 rs2791647 chr1:11132801 G/A cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs200810 0.694 rs4527719 chr6:98020739 C/T cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.64 -4.45 -0.37 1.91e-5 Body mass index; TGCT cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg18654377 chr3:49208889 KLHDC8B -0.38 -4.92 -0.4 2.69e-6 Menarche (age at onset); TGCT cis rs2442825 0.513 rs2648539 chr3:9400424 T/C cg24633833 chr3:10029261 TMEM111 0.5 5.01 0.41 1.83e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs1891275 0.508 rs7099557 chr10:93445364 C/G cg07889827 chr10:93443413 NA -0.33 -6.99 -0.53 1.53e-10 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs646586 chr11:68681653 C/T cg06028808 chr11:68637592 NA -0.51 -6.53 -0.51 1.53e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs60843830 1.000 rs60149603 chr2:285421 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.72 7.02 0.53 1.3100000000000001e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9522267 0.535 rs9522302 chr13:112236874 C/T cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs2046867 0.862 rs28632160 chr3:72800690 T/C cg25664220 chr3:72788482 NA -0.57 -7.12 -0.54 7.61e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2839186 0.934 rs17182538 chr21:47705673 C/A cg13732083 chr21:47605072 C21orf56 0.34 4.48 0.37 1.68e-5 Testicular germ cell tumor; TGCT cis rs763121 0.853 rs9306329 chr22:39072454 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs4383453 0.511 rs6803100 chr3:123103246 T/C cg04890266 chr3:123102914 ADCY5 -0.49 -7.9 -0.58 1.28e-12 Gestational age at birth (maternal effect); TGCT cis rs7666738 0.715 rs3857216 chr4:99032129 G/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2797160 1.000 rs1777226 chr6:126017691 C/A cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs7599312 0.534 rs10207878 chr2:213409337 A/G cg20637307 chr2:213403960 ERBB4 0.92 11.42 0.72 4.43e-21 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9467773 1.000 rs9467787 chr6:26556769 G/T cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.961 rs11130187 chr3:49307872 T/C cg07636037 chr3:49044803 WDR6 0.67 5.41 0.44 3.15e-7 Menarche (age at onset); TGCT cis rs7829975 0.626 rs907183 chr8:8729761 C/G cg08975724 chr8:8085496 FLJ10661 -0.59 -5.63 -0.45 1.16e-7 Mood instability; TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg18722847 chr3:44754129 ZNF502 -0.39 -4.45 -0.37 1.9e-5 Depressive symptoms; TGCT cis rs2364543 0.624 rs61774752 chr1:41847024 T/C cg01193554 chr1:41846683 NA -0.41 -5.01 -0.41 1.86e-6 Intelligence (multi-trait analysis); TGCT cis rs713587 0.806 rs6737082 chr2:25138040 A/C cg01884057 chr2:25150051 NA 0.27 5.33 0.43 4.41e-7 Body mass index in non-asthmatics; TGCT cis rs854765 0.547 rs9894138 chr17:17964345 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.81 -8.63 -0.61 2.55e-14 Total body bone mineral density; TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs644799 1.000 rs481630 chr11:95582447 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.85 8.64 0.61 2.34e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs67311347 0.955 rs1129200 chr3:40532257 T/C cg13683864 chr3:40499215 RPL14 -1.14 -11.17 -0.71 1.81e-20 Renal cell carcinoma; TGCT cis rs1005277 0.579 rs2474588 chr10:38420870 A/G cg13531842 chr10:38383804 ZNF37A -0.38 -4.55 -0.38 1.25e-5 Extrinsic epigenetic age acceleration; TGCT cis rs10114408 0.959 rs10821252 chr9:96652906 G/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs13256369 0.865 rs13277708 chr8:8573936 T/C cg18904891 chr8:8559673 CLDN23 0.6 5.49 0.44 2.19e-7 Obesity-related traits; TGCT cis rs7666738 0.791 rs1593571 chr4:98963763 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2651899 0.934 rs1627080 chr1:3081309 T/C cg07622451 chr1:3079886 PRDM16 0.28 5.51 0.44 1.99e-7 Migraine; TGCT cis rs12950390 0.853 rs12450733 chr17:45855404 A/G cg06532163 chr17:45867833 NA 0.35 5.43 0.44 2.83e-7 IgG glycosylation; TGCT cis rs13242816 1.000 rs13247015 chr7:116095623 A/C cg02799643 chr7:116139180 CAV2 -0.44 -5.22 -0.42 7.16e-7 P wave duration; TGCT cis rs478304 0.903 rs495961 chr11:65540886 C/T cg27068330 chr11:65405492 SIPA1 0.74 7.41 0.55 1.67e-11 Acne (severe); TGCT cis rs7714584 1.000 rs10058943 chr5:150226586 A/G cg22134413 chr5:150180641 NA 0.87 6.89 0.53 2.52e-10 Crohn's disease; TGCT cis rs2486288 0.656 rs8039540 chr15:45551842 C/G cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs12142240 0.698 rs17413694 chr1:46818416 A/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6840360 0.574 rs2709844 chr4:152368212 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs1538970 0.924 rs11211108 chr1:45891152 C/T cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs208520 1.000 rs12199876 chr6:66989469 A/G cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs4665809 1.000 rs6546767 chr2:26328746 A/G cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs1153858 1.000 rs11070453 chr15:45645154 C/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7615952 0.932 rs13065725 chr3:125632289 C/A cg05084668 chr3:125655381 ALG1L -0.63 -4.58 -0.38 1.13e-5 Blood pressure (smoking interaction); TGCT cis rs7954584 0.531 rs10840631 chr12:122373729 C/T cg22618164 chr12:122356400 WDR66 0.69 6.52 0.51 1.6e-9 Mean corpuscular volume; TGCT cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg18252515 chr7:66147081 NA -1.12 -6.49 -0.5 1.83e-9 Diabetic kidney disease; TGCT cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg03517284 chr6:25882590 NA -0.73 -6.67 -0.51 7.4e-10 Intelligence (multi-trait analysis); TGCT cis rs4851266 0.966 rs13017207 chr2:100841235 G/A cg22139774 chr2:100720529 AFF3 -0.35 -5.18 -0.42 8.68e-7 Educational attainment; TGCT cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg23205692 chr1:25664452 TMEM50A 0.51 5.31 0.43 4.88e-7 Erythrocyte sedimentation rate; TGCT cis rs877282 0.853 rs7079450 chr10:755932 T/A cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs4654899 0.772 rs12145203 chr1:21086127 C/T cg01072550 chr1:21505969 NA -0.48 -7.17 -0.54 6.05e-11 Superior frontal gyrus grey matter volume; TGCT cis rs13191362 1.000 rs66789102 chr6:163104432 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.11 9.41 0.65 3.38e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6815814 0.808 rs3860069 chr4:38862121 A/C cg02016764 chr4:38805732 TLR1 -0.33 -5.35 -0.43 4.13e-7 Breast cancer; TGCT trans rs7726839 0.507 rs111707179 chr5:593308 T/A cg11887960 chr12:57824829 NA 1.2 9.65 0.65 8.99e-17 Obesity-related traits; TGCT cis rs7851660 0.527 rs7859751 chr9:100575888 C/T cg13688889 chr9:100608707 NA -0.23 -4.63 -0.38 9.01e-6 Strep throat; TGCT cis rs1023500 0.596 rs133350 chr22:42429049 A/G cg05082376 chr22:42548792 NA -0.22 -5.3 -0.43 5.09e-7 Schizophrenia; TGCT cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs17376456 0.825 rs17372615 chr5:93124768 C/T cg25358565 chr5:93447407 FAM172A 0.91 8.22 0.59 2.27e-13 Diabetic retinopathy; TGCT cis rs4851254 0.660 rs17023468 chr2:100694091 A/G cg22139774 chr2:100720529 AFF3 -0.42 -4.71 -0.39 6.55e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs270601 0.721 rs162894 chr5:131611872 T/G cg24060327 chr5:131705240 SLC22A5 -0.65 -6.56 -0.51 1.32e-9 Acylcarnitine levels; TGCT cis rs7666738 0.791 rs6840669 chr4:99016020 G/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs72781680 0.848 rs72780199 chr2:24016269 A/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs7805747 0.922 rs73728279 chr7:151411494 G/T cg17611936 chr7:151411526 PRKAG2 0.56 6.64 0.51 8.81e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs12477438 0.501 rs2632284 chr2:99775865 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.31 0.77 1.16e-25 Chronic sinus infection; TGCT cis rs9549367 0.789 rs9549701 chr13:113881752 G/C cg00898013 chr13:113819073 PROZ -0.4 -4.88 -0.4 3.18e-6 Platelet distribution width; TGCT cis rs4862750 0.624 rs34414639 chr4:187873417 C/A cg11301795 chr4:187892539 NA -0.34 -5.11 -0.42 1.17e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7954584 0.567 rs10840632 chr12:122375460 C/T cg22618164 chr12:122356400 WDR66 0.69 6.43 0.5 2.52e-9 Mean corpuscular volume; TGCT cis rs12477438 0.520 rs11695751 chr2:99708247 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.0 0.63 3.26e-15 Chronic sinus infection; TGCT cis rs11578119 0.933 rs12126472 chr1:170530053 G/T cg09767346 chr1:170501363 GORAB 0.58 4.56 0.38 1.19e-5 Male-pattern baldness; TGCT cis rs6089829 0.962 rs2314131 chr20:61665225 A/G cg08564027 chr20:61660810 NA 0.3 4.78 0.39 4.9e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg26531700 chr6:26746687 NA -0.5 -4.71 -0.39 6.45e-6 Intelligence (multi-trait analysis); TGCT cis rs7714584 1.000 rs75774363 chr5:150223722 C/T cg22134413 chr5:150180641 NA 0.99 7.43 0.56 1.51e-11 Crohn's disease; TGCT trans rs4650994 1.000 rs17276513 chr1:178520604 A/T cg05059571 chr16:84539110 KIAA1609 0.39 7.24 0.55 4.23e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs12477438 0.765 rs10181344 chr2:99692829 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs6545883 0.894 rs7566035 chr2:61520815 C/T cg15711740 chr2:61764176 XPO1 0.56 4.76 0.39 5.36e-6 Tuberculosis; TGCT cis rs2637266 0.739 rs727902 chr10:78436425 A/C cg18941641 chr10:78392320 NA 0.4 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs10754283 0.756 rs17441836 chr1:90135433 C/T cg03145924 chr1:90228473 NA -0.36 -4.51 -0.38 1.51e-5 Amyotrophic lateral sclerosis (sporadic); TGCT trans rs4332037 0.707 rs4721096 chr7:1877311 T/C cg25206134 chr2:45395956 NA -0.85 -6.62 -0.51 9.68e-10 Bipolar disorder; TGCT cis rs709400 0.663 rs1467561 chr14:103994961 T/C cg26031613 chr14:104095156 KLC1 0.86 9.53 0.65 1.7e-16 Body mass index; TGCT cis rs73036520 0.560 rs346750 chr19:45737218 G/T cg20198684 chr19:45742032 NA -0.24 -4.57 -0.38 1.15e-5 Monocyte percentage of white cells; TGCT trans rs7726839 0.540 rs4957083 chr5:659343 T/C cg11887960 chr12:57824829 NA 1.16 9.4 0.65 3.51e-16 Obesity-related traits; TGCT cis rs7829975 0.742 rs12547493 chr8:8661534 C/T cg08975724 chr8:8085496 FLJ10661 -0.58 -5.4 -0.44 3.31e-7 Mood instability; TGCT cis rs10193935 0.901 rs222468 chr2:42642531 C/T cg27598129 chr2:42591480 NA -0.33 -4.83 -0.4 4.02e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9400180 1.000 rs6568529 chr6:108396166 C/T cg08494708 chr6:108881870 FOXO3 0.51 4.44 0.37 1.93e-5 Major depressive disorder; TGCT cis rs317689 0.718 rs645026 chr12:69757931 G/A cg11871910 chr12:69753446 YEATS4 0.55 4.72 0.39 6.38e-6 Response to diuretic therapy; TGCT cis rs1153858 1.000 rs2066090 chr15:45650018 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs12291225 0.535 rs12806025 chr11:14413817 G/A cg19336497 chr11:14380999 RRAS2 -0.3 -4.64 -0.38 8.58e-6 Sense of smell; TGCT cis rs2404602 0.716 rs12441247 chr15:76812316 T/C cg26408565 chr15:76604113 ETFA -0.4 -5.24 -0.43 6.54e-7 Blood metabolite levels; TGCT cis rs7568458 0.527 rs35416445 chr2:85773659 A/G cg17127132 chr2:85788382 GGCX 0.52 4.63 0.38 9.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs28595532 0.920 rs114223775 chr4:119775091 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs5769707 0.521 rs9616715 chr22:50058582 C/T cg05373962 chr22:49881684 NA -0.32 -5.46 -0.44 2.46e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs72945132 0.769 rs11235754 chr11:70136092 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT trans rs7615952 1.000 rs9289275 chr3:125648659 A/T cg07211511 chr3:129823064 LOC729375 -0.45 -7.63 -0.57 5.35e-12 Blood pressure (smoking interaction); TGCT cis rs9928842 0.771 rs8059190 chr16:75260797 T/A cg09066997 chr16:75300724 BCAR1 0.28 4.96 0.41 2.3e-6 Alcoholic chronic pancreatitis; TGCT trans rs208520 0.731 rs12206488 chr6:66999917 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.84 7.22 0.54 4.62e-11 Exhaled nitric oxide output; TGCT cis rs8177253 1.000 rs1525892 chr3:133484712 C/T cg08048268 chr3:133502702 NA -0.64 -9.75 -0.66 4.97e-17 Iron status biomarkers; TGCT cis rs76473307 1.000 rs6026555 chr20:57418329 G/T cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs1420338 0.967 rs10224203 chr7:34149593 C/T cg01275685 chr7:34179230 BMPER -0.27 -5.11 -0.42 1.17e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs12142240 0.698 rs79490411 chr1:46813568 G/A cg14993813 chr1:46806288 NSUN4 -0.59 -4.74 -0.39 5.85e-6 Menopause (age at onset); TGCT cis rs7412746 0.658 rs3843843 chr1:150918084 C/T cg09365446 chr1:150670422 GOLPH3L 0.35 4.83 0.4 3.87e-6 Melanoma; TGCT cis rs4499344 0.622 rs4805767 chr19:33049056 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.37 -0.5 3.35e-9 Mean platelet volume; TGCT cis rs2070433 0.539 rs2839314 chr21:47961067 A/G cg12379764 chr21:47803548 PCNT 0.53 5.38 0.43 3.6e-7 Lymphocyte counts; TGCT cis rs7312933 0.526 rs1669892 chr12:42811305 G/A cg19980929 chr12:42632907 YAF2 -0.4 -5.7 -0.46 8.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7582180 0.764 rs12712075 chr2:100924129 T/C cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.517 rs4399967 chr4:152729312 T/A cg22705602 chr4:152727874 NA 0.37 6.54 0.51 1.47e-9 Intelligence (multi-trait analysis); TGCT cis rs763014 0.966 rs7185390 chr16:666382 A/G cg27436995 chr16:743998 FBXL16 -0.47 -5.13 -0.42 1.07e-6 Height; TGCT cis rs9527 0.590 rs2182348 chr10:104872684 A/G cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs1008375 0.863 rs7680984 chr4:17600884 A/G cg16339924 chr4:17578868 LAP3 0.82 6.6 0.51 1.09e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg15691649 chr6:25882328 NA -0.42 -5.35 -0.43 4.11e-7 Blood metabolite levels; TGCT cis rs2544527 0.586 rs6728750 chr2:15904734 C/T cg26669897 chr2:15909070 NA 0.37 4.65 0.39 8.39e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs7659604 0.540 rs10004284 chr4:122699222 A/T cg19748678 chr4:122722346 EXOSC9 -0.6 -5.97 -0.47 2.35e-8 Type 2 diabetes; TGCT cis rs1865760 1.000 rs3830057 chr6:25918510 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.11 0.48 1.17e-8 Height; TGCT cis rs4577244 0.505 rs12616009 chr2:29123191 C/G cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer (estrogen-receptor negative); TGCT cis rs6429082 0.738 rs2131921 chr1:235705157 C/T cg26050004 chr1:235667680 B3GALNT2 0.59 5.42 0.44 2.97e-7 Adiposity; TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs72781680 0.752 rs55801864 chr2:23922325 C/T cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT cis rs6754311 0.593 rs12619365 chr2:136398174 C/T cg07169764 chr2:136633963 MCM6 0.68 5.86 0.47 4e-8 Mosquito bite size; TGCT cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg05785598 chr3:49045655 WDR6 0.36 4.81 0.4 4.24e-6 Menarche (age at onset); TGCT cis rs75059851 0.756 rs11223655 chr11:133842707 G/A cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs1153858 1.000 rs11070453 chr15:45645154 C/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs60843830 1.000 rs17714252 chr2:285471 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.74 7.26 0.55 3.77e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2070488 0.766 rs6808093 chr3:38498160 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.79 7.9 0.58 1.3e-12 Electrocardiographic conduction measures; TGCT cis rs7267979 1.000 rs6107045 chr20:25441936 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.532 rs4401299 chr22:42156517 A/G cg06481639 chr22:41940642 POLR3H 0.54 4.49 0.37 1.61e-5 Vitiligo; TGCT cis rs12579753 0.719 rs4384447 chr12:82268069 G/C cg07988820 chr12:82153109 PPFIA2 -0.42 -4.44 -0.37 1.97e-5 Resting heart rate; TGCT cis rs3749237 0.595 rs4855839 chr3:49507847 G/A cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs55823223 0.564 rs1463485 chr17:73851791 C/G cg10935138 chr17:73851978 WBP2 0.82 7.59 0.56 6.81e-12 Psoriasis; TGCT cis rs2153535 0.580 rs4960422 chr6:8459309 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2708977 0.933 rs2464914 chr2:97179828 A/G cg01950434 chr2:97203154 ARID5A -0.69 -6.37 -0.5 3.27e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs870825 0.585 rs2696039 chr4:185610899 T/C cg14471096 chr4:185570637 CCDC111;CASP3 -0.67 -4.62 -0.38 9.41e-6 Blood protein levels; TGCT cis rs465969 1.000 rs459888 chr6:111651156 A/T cg00587628 chr6:111584033 KIAA1919 -0.55 -5.43 -0.44 2.91e-7 Psoriasis; TGCT cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg25660036 chr4:7070649 GRPEL1 -0.67 -5.81 -0.46 4.85e-8 Monocyte percentage of white cells; TGCT cis rs6770219 0.516 rs73182267 chr3:186135453 G/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs10972341 0.933 rs10972339 chr9:35138810 C/T cg00812861 chr9:35114699 KIAA1539 -0.31 -4.54 -0.38 1.33e-5 Weight; TGCT cis rs3617 0.625 rs6769789 chr3:52874446 C/T cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9372498 0.536 rs9489458 chr6:118920503 G/A cg07617317 chr6:118971624 C6orf204 0.49 5.22 0.42 7.37e-7 Diastolic blood pressure; TGCT cis rs1443512 0.773 rs2366146 chr12:54331002 G/A cg17708016 chr12:54321992 NA 0.57 4.67 0.39 7.84e-6 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); TGCT cis rs72901758 0.768 rs11655421 chr17:76251518 T/A cg25512537 chr17:76250053 NA 0.25 4.51 0.38 1.49e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs7772486 0.686 rs9376961 chr6:146048737 C/T cg05347473 chr6:146136440 FBXO30 0.46 4.48 0.37 1.65e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2439831 0.850 rs28524541 chr15:44124831 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT cis rs10540 1.000 rs35811812 chr11:498442 G/A cg03934478 chr11:495069 RNH1 0.35 5.82 0.46 4.66e-8 Body mass index; TGCT cis rs2299587 0.560 rs12718385 chr8:17781257 T/C cg01800426 chr8:17659068 MTUS1 -0.65 -5.78 -0.46 5.68e-8 Economic and political preferences; TGCT cis rs651907 0.557 rs3806654 chr3:101396529 G/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 11.43 0.72 4.08e-21 Colorectal cancer; TGCT cis rs60843830 1.000 rs3791221 chr2:226933 A/G cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.81 0.52 3.78e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7647973 0.626 rs9829155 chr3:49817450 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.75 -0.39 5.61e-6 Menarche (age at onset); TGCT cis rs2239547 0.522 rs6792578 chr3:53004604 G/A cg11645453 chr3:52864694 ITIH4 0.34 5.51 0.44 2.02e-7 Schizophrenia; TGCT cis rs11690935 0.959 rs11897196 chr2:172585595 G/A cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs3782455 1.000 rs75596675 chr12:114401944 A/G cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9291683 0.509 rs998676 chr4:9948564 T/C cg00071950 chr4:10020882 SLC2A9 -0.63 -8.05 -0.59 5.87e-13 Bone mineral density; TGCT cis rs941873 0.772 rs1892498 chr10:81103862 A/G cg09469691 chr10:81107165 PPIF 0.57 5.7 0.46 8.35e-8 Height; TGCT cis rs5769765 1.000 rs2295409 chr22:50261060 G/C cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.07 -0.48 1.47e-8 Schizophrenia; TGCT cis rs700590 0.532 rs10462335 chr5:88088204 G/A cg22951263 chr5:87985283 NA -0.55 -5.64 -0.45 1.09e-7 Educational attainment (years of education); TGCT cis rs6700896 0.522 rs6664534 chr1:66160075 T/A cg14976592 chr1:65886160 LEPROT;LEPR -0.54 -4.44 -0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2463822 0.583 rs72919472 chr11:62040655 C/T cg06239285 chr11:62104954 ASRGL1 -0.88 -5.49 -0.44 2.15e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs17331151 0.573 rs11718060 chr3:52875546 G/A cg11137980 chr3:52469226 SEMA3G 0.27 4.67 0.39 7.79e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11098499 0.722 rs7673476 chr4:120248683 C/T cg09307838 chr4:120376055 NA 0.62 6.09 0.48 1.31e-8 Corneal astigmatism; TGCT cis rs6952808 0.594 rs3778964 chr7:2138109 C/T cg22963979 chr7:1858916 MAD1L1 -0.4 -6.44 -0.5 2.44e-9 Bipolar disorder and schizophrenia; TGCT cis rs9858542 0.537 rs34514189 chr3:49373045 A/G cg00383909 chr3:49044727 WDR6 0.68 4.6 0.38 1.02e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7267979 1.000 rs2500443 chr20:25331442 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4699052 1.000 rs4699055 chr4:104154500 T/C cg16532752 chr4:104119610 CENPE -0.58 -5.46 -0.44 2.43e-7 Testicular germ cell tumor; TGCT cis rs916888 0.773 rs199457 chr17:44795469 C/T cg17911788 chr17:44343683 NA -0.67 -6.98 -0.53 1.62e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg05785598 chr3:49045655 WDR6 -0.36 -4.86 -0.4 3.41e-6 Menarche (age at onset); TGCT cis rs6728642 0.572 rs1320147 chr2:97600626 A/C cg26665480 chr2:98280029 ACTR1B 0.9 6.85 0.52 3.09e-10 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs9581857 0.547 rs1235848 chr13:28111559 G/T cg22138327 chr13:27999177 GTF3A -0.7 -4.81 -0.4 4.22e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT trans rs1814175 0.817 rs12295885 chr11:50036762 T/G cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs2469997 1.000 rs2447168 chr8:120365613 A/T cg00681363 chr8:120844660 TAF2 0.66 4.47 0.37 1.72e-5 Hypertension (SNP x SNP interaction); TGCT trans rs208520 0.661 rs7740835 chr6:66865548 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs2153535 0.541 rs9392222 chr6:8467649 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs910316 1.000 rs4899546 chr14:75594946 G/C cg23033748 chr14:75592666 NEK9 0.28 4.79 0.39 4.73e-6 Height; TGCT cis rs6460942 0.818 rs7780083 chr7:12233647 C/T cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs9297145 0.724 rs6954584 chr7:98766930 G/A cg05967295 chr7:98741636 SMURF1 0.99 12.81 0.75 1.84e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs2120019 0.938 rs8028632 chr15:75321262 T/C cg09165964 chr15:75287851 SCAMP5 -1.14 -10.33 -0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs7674212 0.539 rs7676041 chr4:104126421 T/A cg16532752 chr4:104119610 CENPE -0.57 -5.15 -0.42 9.78e-7 Type 2 diabetes; TGCT cis rs17376456 0.696 rs6860390 chr5:93494731 G/T cg21475434 chr5:93447410 FAM172A -0.58 -5.35 -0.43 4.16e-7 Diabetic retinopathy; TGCT cis rs617219 0.765 rs10053349 chr5:78475423 T/C cg23514016 chr5:78407564 BHMT 0.35 5.53 0.44 1.82e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7584330 0.554 rs9646713 chr2:238443542 T/C cg08992911 chr2:238395768 MLPH 0.64 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs2742417 1.000 rs2673067 chr3:45770087 A/C cg04837898 chr3:45731254 SACM1L -0.47 -4.82 -0.4 4.03e-6 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7072216 0.763 rs3750601 chr10:100174561 C/A cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs9913156 0.793 rs9916135 chr17:4568115 A/C cg00122941 chr17:4613640 ARRB2 -0.89 -7.56 -0.56 7.65e-12 Lymphocyte counts; TGCT trans rs7819412 0.775 rs2001329 chr8:10986859 C/T cg15556689 chr8:8085844 FLJ10661 -0.8 -7.58 -0.56 7.01e-12 Triglycerides; TGCT cis rs1008375 0.966 rs11733730 chr4:17625209 G/C cg16339924 chr4:17578868 LAP3 0.71 5.77 0.46 6.04e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.583 rs2776306 chr21:40713754 A/G cg11890956 chr21:40555474 PSMG1 0.76 7.6 0.56 6.28e-12 Cognitive function; TGCT cis rs2862064 1.000 rs7715467 chr5:156468654 C/G cg12943317 chr5:156479607 HAVCR1 -0.45 -5.29 -0.43 5.36e-7 Platelet count; TGCT cis rs1799949 0.859 rs11657004 chr17:41442751 A/G cg10047753 chr17:41438598 NA 0.87 8.58 0.61 3.31e-14 Menopause (age at onset); TGCT cis rs10193935 0.748 rs12467253 chr2:42697588 A/C cg27598129 chr2:42591480 NA 0.38 5.14 0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9325144 0.555 rs10748433 chr12:38696352 C/G cg26384229 chr12:38710491 ALG10B 0.66 6.16 0.48 9.33e-9 Morning vs. evening chronotype; TGCT cis rs7267979 1.000 rs447722 chr20:25443510 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854765 0.583 rs4257260 chr17:17857003 A/G cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs2239547 0.522 rs6770957 chr3:52995416 T/C cg10802521 chr3:52805072 NEK4 -0.61 -5.9 -0.47 3.2e-8 Schizophrenia; TGCT cis rs6952808 0.609 rs6970034 chr7:1948088 G/A cg22963979 chr7:1858916 MAD1L1 -0.37 -5.62 -0.45 1.22e-7 Bipolar disorder and schizophrenia; TGCT cis rs6582630 0.594 rs7308707 chr12:38450428 G/C cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2797160 0.547 rs9401837 chr6:125956853 T/C cg05901451 chr6:126070800 HEY2 -0.62 -5.17 -0.42 9.25e-7 Endometrial cancer; TGCT cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg00149659 chr3:10157352 C3orf10 0.94 6.04 0.48 1.63e-8 Alzheimer's disease; TGCT cis rs1371867 0.875 rs1788169 chr8:101326314 C/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs10992471 0.756 rs10115222 chr9:95128149 C/T cg14631576 chr9:95140430 CENPP 0.29 4.82 0.4 4.17e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3741404 0.609 rs651855 chr11:63870810 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.73 7.46 0.56 1.34e-11 Platelet count; TGCT cis rs7666738 0.677 rs13120306 chr4:99036099 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.59 0.56 6.7e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7937682 0.961 rs17113227 chr11:111620491 A/G cg09085632 chr11:111637200 PPP2R1B -1.13 -12.51 -0.75 1.02e-23 Primary sclerosing cholangitis; TGCT cis rs66731853 0.771 rs541244 chr1:20889380 G/A cg04087271 chr1:20915334 CDA -0.55 -6.64 -0.51 8.88e-10 Mean corpuscular volume; TGCT cis rs8067545 0.640 rs17759083 chr17:19963605 T/A cg18979559 chr17:20280153 CCDC144C 0.47 4.89 0.4 3e-6 Schizophrenia; TGCT cis rs66573146 0.803 rs59809420 chr4:6969928 G/T cg01220768 chr4:7056774 TADA2B 0.36 4.55 0.38 1.27e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2229238 0.911 rs73023331 chr1:154508210 G/A cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs9682041 0.877 rs12489967 chr3:170073339 A/C cg11886554 chr3:170076028 SKIL 0.59 4.7 0.39 6.84e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs877529 0.530 rs1005300 chr22:39547891 C/G cg18708252 chr22:39545030 CBX7 -0.35 -5.18 -0.42 8.84e-7 Multiple myeloma; TGCT cis rs595982 0.726 rs607356 chr19:49371241 T/C cg17863274 chr19:49399704 TULP2 -0.29 -4.48 -0.37 1.67e-5 Red cell distribution width; TGCT cis rs2354432 0.607 rs58941651 chr1:146784919 T/C cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs9911578 1.000 rs9902994 chr17:56948722 T/A cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs904251 0.772 rs2776906 chr6:37431757 A/G cg01843034 chr6:37503916 NA -0.43 -4.45 -0.37 1.87e-5 Cognitive performance; TGCT trans rs2727020 0.734 rs1164663 chr11:49294723 A/T cg15704280 chr7:45808275 SEPT13 0.67 6.8 0.52 4.02e-10 Coronary artery disease; TGCT cis rs909674 0.690 rs5750825 chr22:39831278 A/G cg05872129 chr22:39784769 NA -0.99 -9.57 -0.65 1.36e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6912958 0.712 rs2814712 chr6:88396322 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.49 4.88 0.4 3.14e-6 Monocyte percentage of white cells; TGCT cis rs1903068 0.657 rs41408948 chr4:55992025 G/A cg01777861 chr4:56023843 NA 0.52 5.58 0.45 1.44e-7 Endometriosis; TGCT cis rs6121246 0.567 rs6060249 chr20:30190944 G/A cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs9486719 1.000 rs11152969 chr6:96908712 A/C cg06623918 chr6:96969491 KIAA0776 -0.98 -8.77 -0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs13242816 1.000 rs13221364 chr7:116083544 C/T cg16553024 chr7:116138462 CAV2 -0.47 -4.72 -0.39 6.27e-6 P wave duration; TGCT cis rs7786808 0.705 rs1377373 chr7:158215549 A/C cg01191920 chr7:158217561 PTPRN2 0.43 6.65 0.51 8.33e-10 Obesity-related traits; TGCT cis rs12497850 0.931 rs9840050 chr3:49133310 A/G cg18654377 chr3:49208889 KLHDC8B -0.41 -5.4 -0.44 3.33e-7 Parkinson's disease; TGCT cis rs9443645 0.901 rs9341754 chr6:79584973 A/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs11614913 0.551 rs1867297 chr12:54396971 A/G cg25285794 chr12:54402699 HOXC8 -0.65 -5.42 -0.44 3.04e-7 Waist circumference adjusted for body mass index; TGCT cis rs7666738 0.830 rs6532721 chr4:99048015 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs589448 0.902 rs2603089 chr12:69776800 C/T cg20891283 chr12:69753455 YEATS4 -0.91 -10.46 -0.68 9.81e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs2354432 0.607 rs3820130 chr1:146724003 A/G cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg09177884 chr7:1199841 ZFAND2A -0.62 -6.45 -0.5 2.24e-9 Longevity;Endometriosis; TGCT cis rs34891900 0.507 rs5992088 chr22:18135912 C/T cg19898043 chr22:18121309 BCL2L13 -0.54 -4.55 -0.38 1.26e-5 Sum neutrophil eosinophil counts; TGCT cis rs8017423 0.569 rs10141476 chr14:90823351 C/T cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs13191362 0.507 rs2849518 chr6:163134248 T/C cg06582575 chr6:163149167 PACRG;PARK2 -0.57 -5.44 -0.44 2.72e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9921338 0.961 rs8048768 chr16:11396840 T/C cg00044050 chr16:11439710 C16orf75 -0.97 -7.11 -0.54 8.2e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs2688608 0.592 rs11000760 chr10:75493734 G/A cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs2075371 0.932 rs2544215 chr7:133987896 T/C cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.25e-9 Mean platelet volume; TGCT cis rs2288073 0.965 rs36101491 chr2:24387532 C/T cg02683114 chr2:24398427 C2orf84 -0.23 -4.94 -0.41 2.52e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs1593573 chr4:98925293 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9611519 0.929 rs2064560 chr22:41530040 A/G cg03806693 chr22:41940476 POLR3H -0.66 -5.97 -0.47 2.28e-8 Neuroticism; TGCT cis rs6074578 0.679 rs6077246 chr20:136454 T/C cg16931068 chr20:139680 DEFB127 0.29 4.94 0.41 2.48e-6 Hirschsprung disease; TGCT cis rs7809950 0.862 rs62482502 chr7:106987810 A/C cg23024343 chr7:107201750 COG5 -0.31 -4.64 -0.38 8.63e-6 Coronary artery disease; TGCT cis rs7772486 0.875 rs13198450 chr6:146370524 C/A cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg14827481 chr10:134361889 INPP5A 0.29 4.66 0.39 8.11e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9549367 0.569 rs3024719 chr13:113814225 G/A cg18105134 chr13:113819100 PROZ -0.46 -7.35 -0.55 2.29e-11 Platelet distribution width; TGCT cis rs916888 0.821 rs199506 chr17:44859031 A/G cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs939658 0.683 rs1434459 chr15:79465210 T/C cg17916960 chr15:79447300 NA -0.42 -6.64 -0.51 8.59e-10 Refractive error; TGCT cis rs2251381 0.722 rs2251278 chr21:30529234 A/G cg08807101 chr21:30365312 RNF160 0.52 4.49 0.37 1.59e-5 Selective IgA deficiency; TGCT cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg22963979 chr7:1858916 MAD1L1 -0.44 -6.93 -0.53 2.01e-10 Bipolar disorder and schizophrenia; TGCT cis rs1218582 0.772 rs2061690 chr1:154919080 C/T cg03351412 chr1:154909251 PMVK 0.5 4.68 0.39 7.52e-6 Prostate cancer; TGCT cis rs12620999 0.555 rs4073396 chr2:238111471 A/C cg23555395 chr2:238036564 NA 0.27 4.75 0.39 5.57e-6 Systemic lupus erythematosus; TGCT cis rs9913156 0.802 rs4538065 chr17:4566015 G/A cg23387401 chr17:4582204 PELP1 -0.31 -4.63 -0.38 8.97e-6 Lymphocyte counts; TGCT cis rs6545883 0.929 rs7606167 chr2:61742654 C/G cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.42 7.06e-7 Tuberculosis; TGCT cis rs72945132 0.882 rs59398290 chr11:70134819 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs295140 0.535 rs1369841 chr2:201227060 A/G cg04283868 chr2:201171347 SPATS2L 0.52 5.1 0.42 1.25e-6 QT interval; TGCT cis rs10791097 0.694 rs12361892 chr11:130744490 T/G cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs9951602 0.541 rs12454297 chr18:76654445 A/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs1990950 1.000 rs1990950 chr5:156920756 G/T cg25387487 chr5:157003181 ADAM19 0.32 4.82 0.4 4.12e-6 Lung function (FEV1/FVC); TGCT cis rs9902453 0.904 rs4077465 chr17:28300144 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.82 7.63 0.57 5.3e-12 Coffee consumption (cups per day); TGCT cis rs12042938 0.905 rs823160 chr1:231776636 A/G cg04892437 chr1:231737901 TSNAX-DISC1 0.44 4.66 0.39 8.13e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs806215 0.547 rs11772303 chr7:127398962 G/T cg11539674 chr7:127291444 SND1 -0.37 -4.72 -0.39 6.35e-6 Type 2 diabetes; TGCT cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg04317338 chr11:64019027 PLCB3 0.75 6.15 0.48 1e-8 Mean platelet volume; TGCT cis rs2299587 0.553 rs2299580 chr8:17734567 C/A cg01800426 chr8:17659068 MTUS1 -0.53 -4.77 -0.39 5.14e-6 Economic and political preferences; TGCT cis rs2997447 0.601 rs61776577 chr1:26431931 T/C cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT cis rs7568458 0.660 rs55692129 chr2:85792404 A/T cg02493740 chr2:85810744 VAMP5 -0.31 -5.81 -0.46 4.94e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9560113 1.000 rs4773387 chr13:112180955 T/C cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs7246657 1.000 rs1823061 chr19:37800626 G/A cg18154014 chr19:37997991 ZNF793 0.81 5.56 0.45 1.61e-7 Coronary artery calcification; TGCT cis rs7959452 0.640 rs4761233 chr12:69722880 T/C cg14784868 chr12:69753453 YEATS4 0.67 6.96 0.53 1.79e-10 Blood protein levels; TGCT cis rs11098499 0.615 rs59867181 chr4:120556467 C/T cg09307838 chr4:120376055 NA -0.57 -5.3 -0.43 5.13e-7 Corneal astigmatism; TGCT cis rs4953076 0.533 rs1551315 chr2:44407618 G/A cg04920474 chr2:44395004 PPM1B 0.59 5.88 0.47 3.58e-8 Height; TGCT cis rs2180341 0.960 rs9398840 chr6:127669744 G/A cg27446573 chr6:127587934 RNF146 1.21 10.87 0.7 9.57e-20 Breast cancer; TGCT cis rs7193541 0.929 rs12933037 chr16:74660174 G/A cg01733217 chr16:74700730 RFWD3 0.83 7.95 0.58 1e-12 Multiple myeloma; TGCT cis rs7824557 0.564 rs2572392 chr8:11235605 T/G cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.95e-9 Retinal vascular caliber; TGCT cis rs7914558 0.966 rs10786719 chr10:104637992 C/T cg05855489 chr10:104503620 C10orf26 -0.51 -4.6 -0.38 1.02e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9926296 0.533 rs7190823 chr16:89866043 A/G cg04287289 chr16:89883240 FANCA 0.94 12.19 0.74 5.77e-23 Vitiligo; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg18722847 chr3:44754129 ZNF502 -0.4 -4.63 -0.38 9.18e-6 Depressive symptoms; TGCT cis rs7954584 0.546 rs10840630 chr12:122352445 C/T cg21016266 chr12:122356598 WDR66 0.53 6.61 0.51 1.04e-9 Mean corpuscular volume; TGCT cis rs155076 0.666 rs4638420 chr13:21872348 A/G cg14456004 chr13:21872349 NA 1.36 12.09 0.74 1.05e-22 White matter hyperintensity burden; TGCT cis rs4499344 0.633 rs259239 chr19:33141090 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.38 0.64 3.96e-16 Mean platelet volume; TGCT cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.6e-6 Menopause (age at onset); TGCT trans rs1814175 0.645 rs12364337 chr11:49942580 A/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs3820928 0.874 rs13413235 chr2:227893863 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs67073037 0.955 rs12611829 chr2:29144456 T/C cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs548987 0.507 rs1408268 chr6:25826986 T/A cg03517284 chr6:25882590 NA -0.55 -4.44 -0.37 1.93e-5 Homocysteine levels; TGCT cis rs8056742 0.558 rs11644136 chr16:85100034 C/T cg00229868 chr16:85520891 NA 0.38 4.76 0.39 5.34e-6 Amyotrophic lateral sclerosis; TGCT cis rs10032931 0.926 rs17024152 chr4:96456402 T/A cg17031751 chr4:96469067 UNC5C -0.37 -4.66 -0.39 7.98e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs12188164 1.000 rs55842567 chr5:437586 G/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.76 -0.39 5.33e-6 Cystic fibrosis severity; TGCT cis rs7267979 1.000 rs2482930 chr20:25334115 G/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7246657 0.943 rs4803460 chr19:37885228 T/C cg18154014 chr19:37997991 ZNF793 0.75 5.34 0.43 4.18e-7 Coronary artery calcification; TGCT cis rs7267979 1.000 rs2258617 chr20:25274318 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2404602 0.692 rs35498563 chr15:76958868 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs36051895 0.632 rs72701654 chr9:5161453 T/C cg02405213 chr9:5042618 JAK2 -0.71 -9.01 -0.63 3.02e-15 Pediatric autoimmune diseases; TGCT cis rs12188164 1.000 rs72717414 chr5:429818 C/G cg21144161 chr5:423903 AHRR 0.26 4.93 0.4 2.59e-6 Cystic fibrosis severity; TGCT cis rs9929218 0.551 rs7201437 chr16:68727130 A/C cg01251360 chr16:68772225 CDH1 -0.28 -5.23 -0.43 6.96e-7 Colorectal cancer; TGCT cis rs7215564 0.818 rs34756632 chr17:78618859 C/T cg23263226 chr17:78226839 SLC26A11 0.45 4.55 0.38 1.26e-5 Myopia (pathological); TGCT cis rs6912958 0.712 rs9444525 chr6:88324142 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.57 -0.38 1.16e-5 Monocyte percentage of white cells; TGCT cis rs4780401 0.587 rs9931332 chr16:11807517 G/C cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs7010267 0.681 rs7842942 chr8:120008587 T/C cg17171407 chr8:119960777 TNFRSF11B 0.27 5.0 0.41 1.9e-6 Total body bone mineral density (age 45-60); TGCT cis rs7010267 0.570 rs10090576 chr8:120037816 T/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs12908161 1.000 rs34570071 chr15:85280212 T/A cg11189052 chr15:85197271 WDR73 0.7 5.71 0.46 7.73e-8 Schizophrenia; TGCT cis rs4728071 0.568 rs3735643 chr7:127224193 A/G cg11539674 chr7:127291444 SND1 -0.4 -4.71 -0.39 6.45e-6 Intelligence (multi-trait analysis); TGCT cis rs236907 0.859 rs3891278 chr1:171756248 A/C cg20598894 chr1:171756153 METTL13 -0.19 -4.47 -0.37 1.72e-5 Mean platelet volume; TGCT cis rs904251 0.600 rs2270687 chr6:37418263 A/G cg08126542 chr6:37504118 NA -0.41 -5.74 -0.46 6.94e-8 Cognitive performance; TGCT cis rs7772486 0.875 rs2777484 chr6:146334162 A/G cg05347473 chr6:146136440 FBXO30 0.55 5.19 0.42 8.36e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg04944784 chr2:26401820 FAM59B -0.73 -6.04 -0.48 1.65e-8 Gut microbiome composition (summer); TGCT cis rs10504229 1.000 rs10504229 chr8:58196495 A/G cg21724239 chr8:58056113 NA 0.38 4.75 0.39 5.6e-6 Developmental language disorder (linguistic errors); TGCT cis rs4808199 0.895 rs4808196 chr19:19476520 G/A cg03709012 chr19:19516395 GATAD2A 0.99 7.6 0.56 6.46e-12 Nonalcoholic fatty liver disease; TGCT cis rs10193935 0.792 rs2053349 chr2:42516205 G/A cg27598129 chr2:42591480 NA -0.39 -5.37 -0.43 3.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs926938 0.584 rs869990 chr1:115379614 A/G cg12756093 chr1:115239321 AMPD1 -0.41 -6.02 -0.48 1.79e-8 Autism; TGCT cis rs2456568 0.802 rs1108910 chr11:93629677 C/T cg17595323 chr11:93583763 C11orf90 0.49 6.44 0.5 2.42e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3749237 0.615 rs11130202 chr3:49566715 C/T cg02487422 chr3:49467188 NICN1 0.6 6.2 0.49 7.76e-9 Resting heart rate; TGCT cis rs7829975 0.564 rs2921057 chr8:8318667 C/T cg06636001 chr8:8085503 FLJ10661 0.8 7.81 0.57 2.09e-12 Mood instability; TGCT cis rs56235845 0.685 rs35630910 chr5:176757841 A/C cg17509989 chr5:176798049 RGS14 0.59 7.97 0.58 8.7e-13 Hemoglobin concentration;Hematocrit; TGCT cis rs5769765 0.955 rs6520066 chr22:50294988 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -11.96 -0.73 2.2e-22 Schizophrenia; TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs904251 0.523 rs1757191 chr6:37482871 C/T cg08126542 chr6:37504118 NA -0.43 -6.28 -0.49 5.34e-9 Cognitive performance; TGCT cis rs28785552 0.800 rs10853854 chr19:53232128 A/G cg22067481 chr19:53234126 ZNF611 0.45 6.71 0.52 6.32e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs3617 0.625 rs6769789 chr3:52874446 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7208859 0.623 rs11657369 chr17:29136468 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3741151 1.000 rs75109191 chr11:73023532 T/C cg17517138 chr11:73019481 ARHGEF17 1.12 5.41 0.44 3.11e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs992157 0.735 rs13388024 chr2:219097773 A/G cg00012203 chr2:219082015 ARPC2 0.81 10.19 0.68 4.34e-18 Colorectal cancer; TGCT cis rs13188771 0.651 rs3912803 chr5:100881268 T/G cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs1903068 0.853 rs12331597 chr4:55997914 T/C cg01777861 chr4:56023843 NA 0.57 6.65 0.51 8.32e-10 Endometriosis; TGCT cis rs950027 0.620 rs1145089 chr15:45652054 G/C cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs7772486 0.846 rs1474871 chr6:146406294 G/A cg05347473 chr6:146136440 FBXO30 0.53 5.03 0.41 1.71e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3806843 0.545 rs251375 chr5:140252960 T/G cg07102913 chr5:140593443 PCDHB13 0.49 4.71 0.39 6.4e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs735396 1.000 rs2259852 chr12:121434833 G/A cg02403541 chr12:121454288 C12orf43 0.66 6.42 0.5 2.59e-9 N-glycan levels; TGCT cis rs7582180 0.663 rs2309794 chr2:100954270 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -5.01 -0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs62380364 0.626 rs618741 chr5:88064012 C/T cg24804195 chr5:87968844 LOC645323 -0.55 -5.34 -0.43 4.23e-7 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.568 rs886950 chr16:89836872 T/C cg27121462 chr16:89883253 FANCA 0.76 8.07 0.59 5.3e-13 Vitiligo; TGCT cis rs994533 0.586 rs17804901 chr2:218262876 C/G cg25097514 chr2:219157373 TMBIM1;PNKD -0.35 -4.5 -0.37 1.52e-5 Height; TGCT cis rs801193 0.660 rs1016265 chr7:66214567 C/T cg18876405 chr7:65276391 NA 0.33 4.97 0.41 2.13e-6 Aortic root size; TGCT cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs6964587 0.967 rs10429103 chr7:91598443 T/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs8177253 0.965 rs4854762 chr3:133499063 A/G cg08048268 chr3:133502702 NA 0.64 9.73 0.66 5.78e-17 Iron status biomarkers; TGCT cis rs60843830 0.928 rs62114494 chr2:211317 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.61 5.14 0.42 1.02e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10992471 0.729 rs6479418 chr9:95064762 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.26 -0.49 5.87e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs854765 0.693 rs8080061 chr17:17776389 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.75 -7.78 -0.57 2.42e-12 Total body bone mineral density; TGCT cis rs12946454 0.621 rs11651809 chr17:43255681 C/G cg10701640 chr17:43249399 NA 0.53 7.14 0.54 6.83e-11 Systolic blood pressure; TGCT cis rs3892630 0.620 rs10413279 chr19:33182746 A/G cg22980127 chr19:33182716 NUDT19 0.8 6.61 0.51 1.04e-9 Red blood cell traits; TGCT cis rs921968 0.643 rs2278530 chr2:219501133 G/A cg02176678 chr2:219576539 TTLL4 0.43 6.12 0.48 1.13e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs9993613 0.875 rs1878759 chr4:73514262 A/G cg15102770 chr4:73434591 ADAMTS3 0.51 4.76 0.39 5.25e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs7178424 0.875 rs7172967 chr15:62218568 A/C cg00456672 chr15:62358751 C2CD4A 0.32 4.87 0.4 3.29e-6 Height; TGCT cis rs2887571 0.955 rs11061819 chr12:1637239 A/C cg01940102 chr12:1095972 NA 0.25 4.66 0.39 8.17e-6 Bone mineral density; TGCT cis rs9527 0.640 rs7089061 chr10:104723015 C/A cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs922182 0.579 rs11856257 chr15:64239941 T/C cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.35e-10 Blood protein levels; TGCT cis rs523522 0.962 rs509445 chr12:121017243 A/C cg12219531 chr12:120966889 COQ5 0.77 6.52 0.51 1.57e-9 High light scatter reticulocyte count; TGCT cis rs10892173 0.566 rs111578166 chr11:117666714 G/T cg21014159 chr11:117668035 DSCAML1 0.61 6.05 0.48 1.61e-8 Myopia; TGCT cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg11890956 chr21:40555474 PSMG1 -0.72 -6.51 -0.5 1.67e-9 Cognitive function; TGCT cis rs612683 0.536 rs12042531 chr1:100965942 G/A cg06223162 chr1:101003688 GPR88 -0.32 -5.28 -0.43 5.51e-7 Breast cancer; TGCT cis rs1971762 0.583 rs7979659 chr12:54086579 A/G cg16917193 chr12:54089295 NA 1.37 18.11 0.85 1.24e-36 Height; TGCT cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg18252515 chr7:66147081 NA 1.17 7.17 0.54 5.94e-11 Diabetic kidney disease; TGCT cis rs2637266 0.846 rs2583051 chr10:78403542 T/C cg18941641 chr10:78392320 NA 0.43 5.58 0.45 1.46e-7 Pulmonary function; TGCT cis rs3135071 1.000 rs3135071 chr4:2406321 C/T cg01601518 chr4:2404284 ZFYVE28 0.53 5.42 0.44 3.04e-7 Influenza A (H1N1) severity; TGCT cis rs8051431 0.876 rs1559398 chr16:72011450 G/A cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs916888 0.773 rs199451 chr17:44801784 G/A cg05721485 chr17:44071124 MAPT 0.26 4.59 0.38 1.06e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4642101 0.662 rs1969154 chr3:12829156 A/G cg05775895 chr3:12838266 CAND2 0.78 8.9 0.62 5.77e-15 QRS complex (12-leadsum); TGCT cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.665 rs6753942 chr2:43749436 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.69 4.58 0.38 1.1e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs1814175 0.546 rs1614397 chr11:49913384 G/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs7707921 0.522 rs12374541 chr5:81491408 A/G cg15871215 chr5:81402204 ATG10 0.25 4.97 0.41 2.22e-6 Breast cancer; TGCT cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg03303774 chr4:1407052 NA 0.33 5.21 0.42 7.7300000000000005e-07 Obesity-related traits; TGCT cis rs28595532 0.920 rs115271785 chr4:119735748 A/T cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs36051895 0.632 rs62541899 chr9:5143291 C/T cg02405213 chr9:5042618 JAK2 -0.7 -9.44 -0.65 2.91e-16 Pediatric autoimmune diseases; TGCT cis rs854765 0.619 rs4561528 chr17:17979099 C/T cg04398451 chr17:18023971 MYO15A -0.36 -6.24 -0.49 6.25e-9 Total body bone mineral density; TGCT cis rs68170813 0.559 rs12536574 chr7:106810997 A/T cg02696742 chr7:106810147 HBP1 -0.69 -5.92 -0.47 2.9e-8 Coronary artery disease; TGCT cis rs362296 0.698 rs3095073 chr4:3263138 C/T cg06533319 chr4:3265114 C4orf44 0.23 4.66 0.39 8.03e-6 Parental longevity (mother's age at death); TGCT cis rs909674 0.818 rs5750833 chr22:39843091 C/A cg01416388 chr22:39784598 NA -0.68 -6.2 -0.49 7.58e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs947211 0.846 rs823155 chr1:205762946 T/C cg14893161 chr1:205819251 PM20D1 0.48 5.26 0.43 6.05e-7 Parkinson's disease; TGCT cis rs56104184 0.830 rs17272658 chr19:49355405 C/T cg17863274 chr19:49399704 TULP2 -0.5 -6.03 -0.48 1.76e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6500602 0.647 rs4785967 chr16:4523208 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.6 0.45 1.28e-7 Schizophrenia; TGCT cis rs9393777 0.513 rs9368450 chr6:26652489 A/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs3845702 0.736 rs2367990 chr2:180843126 C/T cg01881094 chr2:180872142 CWC22 -1.08 -6.92 -0.53 2.19e-10 Schizophrenia; TGCT cis rs9653442 1.000 rs9653442 chr2:100825367 A/G cg07810366 chr2:100720526 AFF3 0.45 7.6 0.56 6.15e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs968567 0.906 rs61897793 chr11:61599347 G/A cg19610905 chr11:61596333 FADS2 -0.79 -5.45 -0.44 2.66e-7 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs9926296 0.527 rs1800335 chr16:89846195 A/G cg27121462 chr16:89883253 FANCA 0.78 8.31 0.6 1.39e-13 Vitiligo; TGCT cis rs9929218 1.000 rs35069703 chr16:68789445 G/A cg01251360 chr16:68772225 CDH1 0.29 4.89 0.4 3.01e-6 Colorectal cancer; TGCT cis rs478304 0.654 rs11227260 chr11:65461158 G/T cg17480646 chr11:65405466 SIPA1 -0.6 -7.95 -0.58 9.79e-13 Acne (severe); TGCT cis rs28595532 0.920 rs17324884 chr4:119771477 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT trans rs1814175 0.791 rs11040472 chr11:49703116 C/T cg03929089 chr4:120376271 NA -0.71 -8.36 -0.6 1.09e-13 Height; TGCT cis rs78761021 0.502 rs12150273 chr17:9765514 G/C cg15743799 chr17:9805578 RCVRN -0.25 -5.32 -0.43 4.6e-7 Type 2 diabetes; TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.31e-6 Prudent dietary pattern; TGCT cis rs6964587 0.626 rs10266424 chr7:91503228 C/T cg17063962 chr7:91808500 NA -0.79 -7.38 -0.55 1.96e-11 Breast cancer; TGCT cis rs7017914 0.902 rs34856835 chr8:71970611 C/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.28 -0.43 5.57e-7 Bone mineral density; TGCT cis rs9952991 0.943 rs9952753 chr18:12780463 A/C cg09945482 chr18:12777974 NA 0.5 4.75 0.39 5.61e-6 Inflammatory skin disease; TGCT cis rs4970988 0.501 rs11204713 chr1:150694623 T/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Urate levels; TGCT cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg03161606 chr19:29218774 NA 0.6 5.84 0.46 4.28e-8 Methadone dose in opioid dependence; TGCT cis rs1050631 1.000 rs1785914 chr18:33700796 A/G cg25426722 chr18:33708991 SLC39A6;ELP2 -0.5 -4.9 -0.4 2.91e-6 Esophageal squamous cell cancer (length of survival); TGCT trans rs629535 0.814 rs62513371 chr8:70077779 T/A cg21567404 chr3:27674614 NA -0.57 -8.99 -0.63 3.38e-15 Dupuytren's disease; TGCT cis rs36051895 0.632 rs11793886 chr9:5125469 A/G cg02405213 chr9:5042618 JAK2 -0.71 -9.55 -0.65 1.57e-16 Pediatric autoimmune diseases; TGCT cis rs3847687 1.000 rs78233646 chr12:131520170 G/T cg25772418 chr12:131519998 GPR133 -0.33 -6.1 -0.48 1.26e-8 Longevity; TGCT trans rs8073060 0.559 rs10438814 chr17:34007065 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9457247 1.000 rs421214 chr6:167396629 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.88 -0.4 3.17e-6 Crohn's disease; TGCT cis rs2404602 0.735 rs11857015 chr15:76649390 T/C cg22467129 chr15:76604101 ETFA 0.51 5.32 0.43 4.58e-7 Blood metabolite levels; TGCT cis rs539096 0.500 rs803678 chr1:44350898 G/T cg13606994 chr1:44402422 ARTN -0.42 -4.52 -0.38 1.44e-5 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.62e-9 Blood metabolite levels; TGCT cis rs8017423 0.967 rs2149655 chr14:90707246 T/C cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs4891159 0.790 rs56077581 chr18:74116865 T/G cg24786174 chr18:74118243 ZNF516 -0.62 -9.41 -0.65 3.36e-16 Longevity; TGCT cis rs68170813 0.641 rs12534124 chr7:107119047 G/A cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 9.98e-7 Coronary artery disease; TGCT cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg01448562 chr3:133502909 NA -0.27 -5.09 -0.42 1.3e-6 Iron status biomarkers; TGCT cis rs950169 0.544 rs2036949 chr15:85163605 T/C cg11189052 chr15:85197271 WDR73 0.75 6.38 0.5 3.2e-9 Schizophrenia; TGCT cis rs11931598 0.509 rs10937771 chr4:6940034 C/T cg26116260 chr4:7069785 GRPEL1 0.64 5.88 0.47 3.61e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs425277 1.000 rs1401138 chr1:2063149 C/T cg03732007 chr1:2071316 PRKCZ 0.25 5.0 0.41 1.92e-6 Height; TGCT cis rs1949733 0.523 rs56053534 chr4:8542876 G/A cg13073564 chr4:8508604 NA 0.5 4.9 0.4 2.96e-6 Response to antineoplastic agents; TGCT cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs12510870 0.635 rs1528915 chr4:74452337 A/T cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs55823223 0.680 rs57287238 chr17:73850940 T/C cg10935138 chr17:73851978 WBP2 1.05 9.62 0.65 1.08e-16 Psoriasis; TGCT cis rs9486715 0.867 rs9373907 chr6:96981189 G/A cg06623918 chr6:96969491 KIAA0776 1.08 14.94 0.8 1.69e-29 Headache; TGCT cis rs12971120 0.891 rs71359051 chr18:72169723 G/A cg26446133 chr18:72167187 CNDP2 -0.37 -6.33 -0.49 4.13e-9 Refractive error; TGCT cis rs9638182 1.000 rs9638180 chr7:72998952 A/G cg14087351 chr7:73037990 MLXIPL -0.56 -4.73 -0.39 6.08e-6 Triglycerides; TGCT cis rs10056811 0.556 rs55810502 chr5:74380959 A/G cg19683494 chr5:74908142 NA 0.62 5.47 0.44 2.39e-7 Coronary artery disease; TGCT cis rs2153535 0.563 rs1737585 chr6:8536594 A/G cg23788917 chr6:8435910 SLC35B3 -0.6 -5.43 -0.44 2.88e-7 Motion sickness; TGCT cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs2535633 0.820 rs7626551 chr3:52938092 C/G cg10802521 chr3:52805072 NEK4 0.58 6.45 0.5 2.27e-9 Body mass index; TGCT cis rs2073300 1.000 rs114718317 chr20:23442620 T/C cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs4906332 1.000 rs12896919 chr14:103956713 T/C cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs10992471 0.603 rs7850528 chr9:95208992 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.59 -5.36 -0.43 3.84e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10465746 0.967 rs6670658 chr1:84461268 A/G cg10977910 chr1:84465055 TTLL7 0.67 6.78 0.52 4.26e-10 Obesity-related traits; TGCT cis rs7267979 0.932 rs449370 chr20:25451180 A/G cg16686733 chr20:25566563 NINL -0.58 -5.85 -0.47 4.09e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7611238 0.560 rs10439949 chr3:195080491 T/C cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs6540559 0.673 rs6540561 chr1:209982255 C/T cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs12478296 1.000 rs55814222 chr2:243041166 C/T cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs981844 0.712 rs4616729 chr4:154746900 T/G cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs910316 0.737 rs108621 chr14:75480637 T/C cg08847533 chr14:75593920 NEK9 -0.84 -8.67 -0.61 2.03e-14 Height; TGCT cis rs6598955 0.543 rs6698557 chr1:26561220 G/C cg04990556 chr1:26633338 UBXN11 0.83 8.1 0.59 4.29e-13 Obesity-related traits; TGCT cis rs1525293 0.965 rs6944601 chr7:70489980 A/T cg21135135 chr7:70597687 WBSCR17 0.48 4.78 0.39 4.89e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs12681287 0.752 rs67615966 chr8:87255203 C/A cg27223183 chr8:87520930 FAM82B -0.81 -5.66 -0.45 9.9e-8 Caudate activity during reward; TGCT cis rs1577917 0.958 rs34795473 chr6:86461799 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.69 -5.59 -0.45 1.39e-7 Response to antipsychotic treatment; TGCT trans rs208520 1.000 rs72882100 chr6:66981495 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg23172400 chr8:95962367 TP53INP1 -0.36 -6.07 -0.48 1.44e-8 Type 2 diabetes; TGCT cis rs4889911 1.000 rs4889910 chr17:77839795 C/T cg00646381 chr17:77835854 NA 0.37 5.56 0.45 1.61e-7 Electroencephalogram traits; TGCT cis rs12620999 0.627 rs7570274 chr2:238103614 G/C cg23555395 chr2:238036564 NA -0.28 -4.95 -0.41 2.4e-6 Systemic lupus erythematosus; TGCT cis rs3008870 1.000 rs2985822 chr1:67404910 T/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.97 0.73 2.07e-22 Lymphocyte percentage of white cells; TGCT cis rs1801251 1.000 rs6724117 chr2:233593660 T/G cg25237894 chr2:233734115 C2orf82 0.32 5.81 0.46 4.94e-8 Coronary artery disease; TGCT cis rs7085104 0.684 rs7092690 chr10:104609365 T/C cg05855489 chr10:104503620 C10orf26 0.51 4.54 0.38 1.34e-5 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7909074 0.831 rs7903412 chr10:45382361 C/T cg05187965 chr10:45406764 TMEM72 -0.27 -5.76 -0.46 6.14e-8 Mean corpuscular volume; TGCT cis rs7914558 1.000 rs10509757 chr10:104752960 C/T cg04362960 chr10:104952993 NT5C2 0.59 5.19 0.42 8.49e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs7727544 0.735 rs270605 chr5:131651811 C/T cg14196790 chr5:131705035 SLC22A5 0.32 4.44 0.37 1.94e-5 Blood metabolite levels; TGCT cis rs9611565 0.802 rs132916 chr22:41806768 C/G cg13695892 chr22:41940480 POLR3H 0.78 7.93 0.58 1.07e-12 Vitiligo; TGCT cis rs10501293 1.000 rs4495880 chr11:43133626 A/C cg03447554 chr11:43094025 NA -0.48 -6.72 -0.52 5.89e-10 Cognitive performance; TGCT cis rs174601 0.615 rs174534 chr11:61549458 C/T cg01500311 chr11:61656094 FADS3 0.26 4.77 0.39 5.07e-6 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs6688613 0.721 rs2312675 chr1:166922533 T/C cg07049167 chr1:166818506 POGK 0.23 4.94 0.41 2.49e-6 Refractive astigmatism; TGCT cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.48 6.49 0.5 1.83e-9 Alzheimer's disease; TGCT cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg13695892 chr22:41940480 POLR3H -0.9 -9.03 -0.63 2.7e-15 Vitiligo; TGCT cis rs61990749 0.597 rs6574391 chr14:78208121 G/A cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs11785400 1.000 rs4557682 chr8:143738182 T/C cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs10782582 0.593 rs17848068 chr1:76190216 G/A cg22875332 chr1:76189707 ACADM -0.5 -5.71 -0.46 7.83e-8 Daytime sleep phenotypes; TGCT cis rs3749237 0.964 rs2352967 chr3:49871641 C/T cg07636037 chr3:49044803 WDR6 0.62 5.51 0.44 2.02e-7 Resting heart rate; TGCT cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg15782153 chr7:917662 C7orf20 0.46 5.4 0.44 3.33e-7 Perceived unattractiveness to mosquitoes; TGCT cis rs9894429 0.934 rs35868252 chr17:79575472 C/G cg18240062 chr17:79603768 NPLOC4 -0.67 -6.84 -0.52 3.23e-10 Eye color traits; TGCT cis rs1153858 1.000 rs56669689 chr15:45637729 A/C cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.24e-9 Blood metabolite levels; TGCT cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg13695892 chr22:41940480 POLR3H -0.84 -7.96 -0.58 9.47e-13 Vitiligo; TGCT cis rs651907 0.557 rs34457525 chr3:101435225 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.73 0.39 5.91e-6 Colorectal cancer; TGCT cis rs4891159 0.756 rs3892540 chr18:74118058 C/T cg24786174 chr18:74118243 ZNF516 -0.62 -9.38 -0.64 3.96e-16 Longevity; TGCT cis rs7680126 0.596 rs4637402 chr4:10045430 C/T cg11266682 chr4:10021025 SLC2A9 0.5 4.78 0.39 4.89e-6 Urate levels in lean individuals;Urate levels in overweight individuals;Urate levels in obese individuals; TGCT cis rs4808199 0.948 rs968525 chr19:19459215 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.67 5.27 0.43 5.81e-7 Nonalcoholic fatty liver disease; TGCT cis rs453301 0.512 rs2921381 chr8:8895401 T/A cg06636001 chr8:8085503 FLJ10661 0.71 6.23 0.49 6.75e-9 Joint mobility (Beighton score); TGCT cis rs1018836 0.668 rs9297857 chr8:91480964 A/C cg16814680 chr8:91681699 NA -0.78 -8.02 -0.58 6.64e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs11249608 0.548 rs10516150 chr5:178459169 G/C cg23951258 chr5:178450506 ZNF879 0.44 4.56 0.38 1.23e-5 Pubertal anthropometrics; TGCT cis rs11690935 0.655 rs12052995 chr2:172537212 A/G cg13550731 chr2:172543902 DYNC1I2 0.69 6.07 0.48 1.45e-8 Schizophrenia; TGCT cis rs10504229 0.593 rs7000752 chr8:58026980 C/G cg08280861 chr8:58055591 NA 0.32 4.57 0.38 1.15e-5 Developmental language disorder (linguistic errors); TGCT cis rs7072216 0.763 rs2274246 chr10:100175060 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs9468199 0.510 rs77576207 chr6:27842155 G/T cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs28735056 1.000 rs59183289 chr18:77631198 A/G cg20368463 chr18:77673604 PQLC1 -0.47 -5.84 -0.46 4.22e-8 Schizophrenia; TGCT cis rs72781680 0.821 rs72796401 chr2:24180078 T/A cg08917208 chr2:24149416 ATAD2B 0.77 4.77 0.39 5.02e-6 Lymphocyte counts; TGCT cis rs8177253 0.965 rs8177245 chr3:133479230 A/G cg20276088 chr3:133502917 NA -0.24 -4.96 -0.41 2.28e-6 Iron status biomarkers; TGCT cis rs651907 1.000 rs651907 chr3:101600724 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.46 4.64 0.38 8.78e-6 Colorectal cancer; TGCT trans rs4824093 0.610 rs60036544 chr22:50264019 C/T cg09872104 chr7:134855509 C7orf49 -0.94 -7.68 -0.57 4.2e-12 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg13732083 chr21:47605072 C21orf56 0.37 4.87 0.4 3.31e-6 Testicular germ cell tumor; TGCT cis rs4889911 0.544 rs1294081 chr17:77829864 T/C cg00646381 chr17:77835854 NA 0.44 6.6 0.51 1.06e-9 Electroencephalogram traits; TGCT cis rs1865760 0.622 rs9968910 chr6:26072095 A/C cg17042849 chr6:26104293 HIST1H4C -0.85 -7.52 -0.56 9.57e-12 Height; TGCT cis rs12693043 0.727 rs3087907 chr2:175424779 T/G cg11778734 chr2:175439522 WIPF1 -0.38 -4.89 -0.4 3.05e-6 Urate levels (BMI interaction); TGCT trans rs1814175 0.817 rs10769641 chr11:49960141 A/G cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs7208859 0.673 rs11080138 chr17:29224542 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1552244 0.554 rs55847233 chr3:9991101 C/G cg00149659 chr3:10157352 C3orf10 0.67 4.94 0.41 2.48e-6 Alzheimer's disease; TGCT cis rs9443645 0.901 rs4147183 chr6:79557046 C/G cg09184832 chr6:79620586 NA -0.48 -5.35 -0.43 4.01e-7 Intelligence (multi-trait analysis); TGCT cis rs2305707 0.867 rs1054984 chr15:51551127 T/A cg19946085 chr15:51559439 CYP19A1 0.49 5.15 0.42 9.79e-7 Height; TGCT cis rs3617 0.573 rs62253583 chr3:52928334 G/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.67 -0.39 7.82e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.790 rs2253768 chr6:146199922 A/G cg23711669 chr6:146136114 FBXO30 0.95 10.8 0.7 1.46e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs826838 0.834 rs826874 chr12:39122599 C/A cg26384229 chr12:38710491 ALG10B -0.87 -7.93 -0.58 1.08e-12 Heart rate; TGCT trans rs1814175 0.817 rs1621090 chr11:49895868 C/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.63e-13 Height; TGCT cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs6725041 0.819 rs11677623 chr2:213082372 A/G cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs1218582 0.741 rs705094 chr1:154917314 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.64 -6.53 -0.51 1.52e-9 Prostate cancer; TGCT cis rs5769765 0.908 rs138889 chr22:50226673 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.05 -11.2 -0.71 1.49e-20 Schizophrenia; TGCT cis rs9902453 0.838 rs3110495 chr17:27978455 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.69 -6.41 -0.5 2.74e-9 Coffee consumption (cups per day); TGCT cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs7312933 0.558 rs1669936 chr12:42813509 C/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.69 -0.46 8.61e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs523522 0.962 rs670568 chr12:121021206 C/T cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs7584330 0.554 rs75918156 chr2:238426287 G/A cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs9611565 0.592 rs1811113 chr22:42073134 C/T cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Vitiligo; TGCT cis rs1511802 0.614 rs12507156 chr4:187116832 C/T cg19358738 chr4:186734530 SORBS2 0.18 4.59 0.38 1.09e-5 Blood protein levels; TGCT cis rs3796352 0.686 rs1560333 chr3:53138254 T/C cg27565382 chr3:53032988 SFMBT1 -0.38 -4.54 -0.38 1.33e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7586879 0.964 rs4077679 chr2:25122852 T/C cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg13695892 chr22:41940480 POLR3H -0.92 -9.08 -0.63 2.06e-15 Vitiligo; TGCT cis rs7104764 1.000 rs6598061 chr11:243853 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs11676348 0.846 rs3890158 chr2:218990292 G/A cg00012203 chr2:219082015 ARPC2 -0.51 -4.85 -0.4 3.59e-6 Ulcerative colitis; TGCT cis rs595982 0.559 rs17206700 chr19:49361255 A/G cg17863274 chr19:49399704 TULP2 -0.47 -6.71 -0.52 6.21e-10 Red cell distribution width; TGCT cis rs7267979 0.586 rs11087505 chr20:25196520 T/A cg16686733 chr20:25566563 NINL 0.51 5.12 0.42 1.16e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs1008375 0.931 rs6813374 chr4:17649494 T/C cg10189774 chr4:17578691 LAP3 0.6 5.29 0.43 5.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs67311347 1.000 rs10510708 chr3:40404770 A/G cg17264618 chr3:40429014 ENTPD3 0.31 4.65 0.39 8.38e-6 Renal cell carcinoma; TGCT cis rs78487399 0.808 rs17030818 chr2:43680318 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6558530 0.965 rs6558529 chr8:1706206 C/T cg09410841 chr8:1729607 CLN8 0.87 9.5 0.65 2e-16 Systolic blood pressure; TGCT cis rs11577318 0.853 rs12743998 chr1:26629882 G/A cg04990556 chr1:26633338 UBXN11 -0.63 -5.83 -0.46 4.58e-8 Granulocyte percentage of myeloid white cells; TGCT trans rs916888 0.687 rs199456 chr17:44797919 C/T cg10053473 chr17:62856997 LRRC37A3 -0.47 -6.89 -0.53 2.48e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4780355 0.918 rs243323 chr16:11361202 A/G cg00044050 chr16:11439710 C16orf75 0.54 4.77 0.39 5.01e-6 Crohn's disease and psoriasis; TGCT cis rs2820315 1.000 rs2820295 chr1:201800868 G/A cg12730843 chr1:201915899 LMOD1 -0.27 -4.81 -0.4 4.22e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs10782582 0.593 rs114421765 chr1:76141802 C/T cg22875332 chr1:76189707 ACADM -0.54 -6.17 -0.48 8.76e-9 Daytime sleep phenotypes; TGCT cis rs7312933 0.558 rs1796382 chr12:42840955 C/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.7 -0.46 8.41e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs28595532 0.764 rs116158926 chr4:119730572 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg07061783 chr6:25882402 NA 0.72 7.4 0.55 1.8e-11 Blood metabolite levels; TGCT cis rs769267 0.930 rs4808967 chr19:19640524 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.6 0.45 1.31e-7 Tonsillectomy; TGCT cis rs4727027 0.933 rs9718383 chr7:148857624 A/T cg23583168 chr7:148888333 NA 0.77 10.15 0.67 5.62e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9788682 0.948 rs59683676 chr15:78833453 T/C cg06917634 chr15:78832804 PSMA4 -0.7 -4.86 -0.4 3.47e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs6546537 0.824 rs13011186 chr2:69778558 C/T cg10773587 chr2:69614142 GFPT1 -0.81 -8.18 -0.59 2.84e-13 Serum thyroid-stimulating hormone levels; TGCT cis rs1218582 0.803 rs7531728 chr1:154840516 C/A cg09359103 chr1:154839909 KCNN3 -0.7 -14.59 -0.79 1.13e-28 Prostate cancer; TGCT cis rs7542091 0.704 rs7550330 chr1:210044587 G/A cg21951975 chr1:209979733 IRF6 0.6 6.1 0.48 1.24e-8 Monobrow; TGCT cis rs10927875 0.562 rs10803401 chr1:16147377 G/A cg14742211 chr1:16348397 CLCNKA -0.2 -4.79 -0.39 4.75e-6 Dilated cardiomyopathy; TGCT cis rs208515 0.556 rs1872309 chr6:66660432 A/C cg07460842 chr6:66804631 NA 0.73 7.21 0.54 4.72e-11 Exhaled nitric oxide levels; TGCT cis rs597539 0.617 rs598353 chr11:68635770 C/A cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg06873352 chr17:61820015 STRADA 0.59 6.56 0.51 1.31e-9 Prudent dietary pattern; TGCT cis rs748404 0.660 rs2439846 chr15:43740970 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs7302981 0.934 rs7294548 chr12:50543201 A/G cg23855989 chr12:50355821 AQP5 -0.3 -4.5 -0.38 1.52e-5 Systolic blood pressure; TGCT cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg10802521 chr3:52805072 NEK4 -0.78 -10.09 -0.67 7.59e-18 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.791 rs6851549 chr4:99029827 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12971120 0.891 rs12605820 chr18:72167802 G/A cg25817165 chr18:72167213 CNDP2 -0.29 -4.98 -0.41 2.05e-6 Refractive error; TGCT cis rs9549260 0.755 rs7317254 chr13:41217849 A/G cg21288729 chr13:41239152 FOXO1 0.99 10.37 0.68 1.56e-18 Red blood cell count; TGCT cis rs16867321 0.614 rs10204086 chr2:181449668 G/T cg23363182 chr2:181467187 NA -0.41 -6.04 -0.48 1.69e-8 Obesity; TGCT cis rs7772486 0.875 rs6930975 chr6:146387111 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.59 0.65 1.22e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs17270561 0.562 rs12199626 chr6:26013604 G/A cg16482183 chr6:26056742 HIST1H1C 0.98 7.33 0.55 2.6e-11 Iron status biomarkers; TGCT cis rs7208859 0.623 rs609063 chr17:28951513 A/G cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9883204 0.817 rs10934647 chr3:123130684 C/T cg04890266 chr3:123102914 ADCY5 0.36 5.08 0.42 1.34e-6 Birth weight; TGCT cis rs483180 0.859 rs478093 chr1:120255126 C/T cg19096424 chr1:120255104 PHGDH -0.57 -5.27 -0.43 5.95e-7 Macular telangiectasia type 2; TGCT cis rs12908161 1.000 rs11632465 chr15:85282045 A/T cg17173187 chr15:85201210 NMB 0.57 6.38 0.5 3.25e-9 Schizophrenia; TGCT cis rs6867032 0.876 rs1552435 chr5:2018378 A/G cg26168224 chr5:2018326 NA 0.44 8.03 0.59 6.26e-13 Gut microbiome composition (winter); TGCT cis rs78456975 0.506 rs10167704 chr2:1571037 G/C cg01028140 chr2:1542097 TPO -0.33 -5.02 -0.41 1.77e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs12497850 0.931 rs4974082 chr3:48999323 G/A cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.91e-6 Parkinson's disease; TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs7698623 0.702 rs4693884 chr4:88770229 C/T cg27387453 chr4:88533842 DSPP 0.61 4.6 0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs33794 0.901 rs33774 chr3:45286107 C/T cg18645101 chr3:44551900 NA 0.54 4.67 0.39 7.71e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs7729723 0.533 rs11242429 chr5:137821271 T/C cg19169342 chr5:137827400 NA 0.32 4.46 0.37 1.78e-5 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs6545883 0.965 rs1562308 chr2:61768421 A/C cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs2115630 0.645 rs3825878 chr15:85174755 C/T cg12863693 chr15:85201151 NMB -0.39 -5.11 -0.42 1.19e-6 P wave terminal force; TGCT cis rs1218582 0.772 rs1976559 chr1:154879788 A/T cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs8072100 0.582 rs3826536 chr17:45501967 T/A cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg11644478 chr21:40555479 PSMG1 1.07 10.81 0.7 1.32e-19 Cognitive function; TGCT cis rs3617 0.573 rs13072537 chr3:52896032 C/A cg10802521 chr3:52805072 NEK4 -0.57 -6.58 -0.51 1.21e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9467711 0.790 rs13195401 chr6:26463574 G/T cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs2486012 1.000 rs2906456 chr1:44340920 C/T cg12908607 chr1:44402522 ARTN 0.67 5.42 0.44 2.93e-7 Intelligence (multi-trait analysis); TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg01802117 chr1:53393560 SCP2 -0.4 -4.72 -0.39 6.33e-6 Monocyte count; TGCT cis rs1035144 0.505 rs2268459 chr14:81463041 A/G cg06600135 chr14:81408086 NA -0.48 -4.48 -0.37 1.64e-5 Male sexual orientation; TGCT cis rs1395 0.710 rs1992291 chr2:27504312 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.58 7.24 0.55 4.04e-11 Blood metabolite levels; TGCT cis rs9972944 0.656 rs10083855 chr17:63773139 T/C cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs514475 0.526 rs9688555 chr6:137956470 A/G cg02673417 chr6:137105249 MAP3K5 -0.29 -4.44 -0.37 1.98e-5 Inflammatory skin disease; TGCT cis rs4242434 1.000 rs4242434 chr8:22501830 C/A cg03733263 chr8:22462867 KIAA1967 1.16 17.73 0.85 8.57e-36 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs4849845 0.637 rs11688038 chr2:121026582 A/G cg24070213 chr2:121070622 NA 0.35 4.8 0.4 4.43e-6 Mean platelet volume; TGCT cis rs55823223 0.564 rs936396 chr17:73846829 C/G cg10935138 chr17:73851978 WBP2 0.82 7.57 0.56 7.35e-12 Psoriasis; TGCT cis rs4631830 0.720 rs2843560 chr10:51512129 C/G cg10326726 chr10:51549505 MSMB 0.23 4.5 0.37 1.54e-5 Prostate-specific antigen levels; TGCT cis rs9486719 1.000 rs11153058 chr6:97012746 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs11098499 0.866 rs7665125 chr4:120402079 G/T cg09307838 chr4:120376055 NA 0.62 6.1 0.48 1.24e-8 Corneal astigmatism; TGCT trans rs9388451 0.807 rs1268070 chr6:126041164 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.74 -7.47 -0.56 1.24e-11 Brugada syndrome; TGCT cis rs1008375 1.000 rs6848360 chr4:17634442 G/T cg16339924 chr4:17578868 LAP3 0.71 5.75 0.46 6.46e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4888262 0.545 rs12716768 chr16:74556486 A/G cg01733217 chr16:74700730 RFWD3 -0.69 -6.62 -0.51 9.96e-10 Testicular germ cell tumor; TGCT cis rs4711350 0.765 rs2182658 chr6:33748831 G/T cg18005901 chr6:33739558 LEMD2 0.59 6.65 0.51 8.49e-10 Schizophrenia; TGCT cis rs2204008 0.683 rs11519834 chr12:38053575 T/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT trans rs1814175 0.645 rs10128563 chr11:50023681 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs2458413 0.771 rs7010076 chr8:105342827 C/G cg23108931 chr8:105342351 NA -0.36 -6.26 -0.49 5.85e-9 Paget's disease; TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs7666738 0.753 rs10033138 chr4:98981922 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 1.000 rs6739061 chr2:26256147 C/T cg25036284 chr2:26402008 FAM59B -0.55 -4.76 -0.39 5.33e-6 Gut microbiome composition (summer); TGCT cis rs7772486 0.686 rs1011596 chr6:146076433 A/G cg05347473 chr6:146136440 FBXO30 0.51 4.69 0.39 7.21e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6545883 1.000 rs778762 chr2:61782921 G/T cg15711740 chr2:61764176 XPO1 -0.56 -5.14 -0.42 1.06e-6 Tuberculosis; TGCT cis rs796364 0.951 rs281776 chr2:200834282 T/G cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs2749592 0.918 rs1208653 chr10:38253826 C/G cg25427524 chr10:38739819 LOC399744 0.33 4.95 0.41 2.38e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs4319547 0.661 rs10846830 chr12:122897220 C/G cg05707623 chr12:122985044 ZCCHC8 -0.63 -4.94 -0.41 2.46e-6 Body mass index; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg20007245 chr22:24372913 LOC391322 -0.76 -7.82 -0.57 1.93e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3733585 0.604 rs73215003 chr4:10126317 C/G cg11266682 chr4:10021025 SLC2A9 -0.54 -6.23 -0.49 6.59e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs71636778 0.509 rs11538549 chr1:27248283 C/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs7267979 0.657 rs6107073 chr20:25716363 T/C cg21995068 chr20:25989032 LOC100134868 -0.41 -5.11 -0.42 1.18e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg00343986 chr7:65444356 GUSB 0.26 6.07 0.48 1.42e-8 Calcium levels; TGCT cis rs17376456 0.597 rs10866760 chr5:93338335 G/A cg09848695 chr5:92956644 FAM172A;MIR2277 -0.54 -4.58 -0.38 1.11e-5 Diabetic retinopathy; TGCT cis rs2404602 0.583 rs2456076 chr15:76557553 T/G cg26408565 chr15:76604113 ETFA 0.47 6.51 0.5 1.65e-9 Blood metabolite levels; TGCT cis rs427394 0.802 rs274712 chr5:6723950 G/A cg10857441 chr5:6722123 POLS -0.32 -7.93 -0.58 1.08e-12 Menopause (age at onset); TGCT cis rs10510102 0.872 rs116521083 chr10:123710126 A/C cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs368123 0.686 rs2774226 chr6:160700386 G/A cg19643109 chr6:160697625 NA -0.2 -4.82 -0.4 4.06e-6 Waist circumference; TGCT cis rs1552244 0.554 rs3732963 chr3:10048885 G/T cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs10876993 1.000 rs10876993 chr12:58062667 C/T cg15848620 chr12:58087721 OS9 -0.7 -5.61 -0.45 1.28e-7 Celiac disease or Rheumatoid arthritis; TGCT cis rs6163 0.588 rs11191392 chr10:104526951 C/A cg05855489 chr10:104503620 C10orf26 1.02 12.83 0.76 1.7e-24 Waist circumference;Hip circumference; TGCT cis rs11264213 0.901 rs72661613 chr1:36364781 A/G cg26235710 chr1:36184717 C1orf216 1.06 4.47 0.37 1.72e-5 Schizophrenia; TGCT cis rs7193541 0.965 rs28616016 chr16:74676964 T/C cg01733217 chr16:74700730 RFWD3 0.8 7.74 0.57 2.95e-12 Multiple myeloma; TGCT cis rs11122272 0.735 rs11122281 chr1:231519842 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs116095464 0.558 rs1968374 chr5:249025 A/C cg12570787 chr5:219185 SDHA;CCDC127 0.73 4.64 0.38 8.88e-6 Breast cancer; TGCT cis rs394563 0.591 rs6570964 chr6:149691859 G/A cg03678062 chr6:149772716 ZC3H12D 0.38 4.8 0.4 4.4e-6 Dupuytren's disease; TGCT cis rs6690583 0.623 rs12042160 chr1:85504516 A/G cg20280350 chr1:85513789 MCOLN3 -0.71 -4.58 -0.38 1.1e-5 Serum sulfate level; TGCT cis rs4494114 0.967 rs6663796 chr1:39312887 T/C cg25970120 chr1:39325951 RRAGC -0.6 -6.43 -0.5 2.52e-9 Blood protein levels; TGCT cis rs11105298 0.891 rs11105325 chr12:89938590 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.74 -5.27 -0.43 5.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6752107 0.935 rs11690131 chr2:234148383 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.91 0.4 2.8e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs797680 0.786 rs4847240 chr1:93817946 A/G cg17826107 chr1:92977322 EVI5 -0.24 -5.65 -0.45 1.05e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs910316 0.875 rs12588099 chr14:75594462 A/T cg11812906 chr14:75593930 NEK9 0.73 7.23 0.54 4.33e-11 Height; TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg16325326 chr1:53192061 ZYG11B 0.59 7.1 0.54 8.48e-11 Monocyte count; TGCT cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs8103278 1.000 rs17571725 chr19:46290822 C/T cg14061069 chr19:46274453 DMPK -0.43 -6.14 -0.48 1.04e-8 Coronary artery disease; TGCT cis rs2243480 1.000 rs73142122 chr7:65311298 C/A cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT cis rs3885907 0.542 rs9315046 chr13:31320543 G/A cg22282089 chr13:30686841 NA -0.22 -4.57 -0.38 1.16e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT cis rs9868809 0.772 rs9812977 chr3:48720303 G/A cg00383909 chr3:49044727 WDR6 1.36 6.75 0.52 5.01e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9910055 0.530 rs7222349 chr17:42304644 C/T cg19774624 chr17:42201019 HDAC5 -0.7 -7.42 -0.55 1.61e-11 Total body bone mineral density; TGCT cis rs2013441 1.000 rs2058971 chr17:20219508 T/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT trans rs61931739 0.500 rs11513287 chr12:34584351 G/A cg26384229 chr12:38710491 ALG10B 0.72 6.67 0.51 7.67e-10 Morning vs. evening chronotype; TGCT cis rs9993613 0.778 rs13105983 chr4:73420634 G/A cg15102770 chr4:73434591 ADAMTS3 0.52 4.63 0.38 9.11e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs7829975 0.539 rs940031 chr8:8546848 C/T cg17143192 chr8:8559678 CLDN23 -0.52 -5.25 -0.43 6.37e-7 Mood instability; TGCT cis rs875971 1.000 rs2420168 chr7:65630631 C/G cg18876405 chr7:65276391 NA -0.33 -4.99 -0.41 1.97e-6 Aortic root size; TGCT cis rs10779751 0.734 rs1130683 chr1:11132217 G/A cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs933688 1.000 rs1035477 chr5:90743325 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.25 0.6 1.91e-13 Smoking behavior; TGCT cis rs72615157 0.612 rs7786505 chr7:99817585 G/T cg00814883 chr7:100076585 TSC22D4 -0.55 -5.42 -0.44 3.01e-7 Lung function (FEV1/FVC); TGCT cis rs10904908 0.931 rs7903137 chr10:17259567 C/T cg01003015 chr10:17271136 VIM -0.52 -4.52 -0.38 1.44e-5 Total cholesterol levels;Cholesterol, total; TGCT cis rs8180040 0.902 rs73081205 chr3:47517670 A/C cg27129171 chr3:47204927 SETD2 -0.66 -7.84 -0.58 1.75e-12 Colorectal cancer; TGCT cis rs782590 0.807 rs782572 chr2:55912120 T/C cg18811423 chr2:55921094 PNPT1 0.72 8.16 0.59 3.21e-13 Metabolic syndrome; TGCT cis rs76419734 0.850 rs17331332 chr4:106808107 A/G cg24545054 chr4:106630052 GSTCD;INTS12 -1.01 -4.61 -0.38 9.71e-6 Post bronchodilator FEV1; TGCT cis rs939658 1.000 rs939658 chr15:79451869 A/G cg17916960 chr15:79447300 NA 0.53 8.37 0.6 1.04e-13 Refractive error; TGCT cis rs6095298 0.595 rs11905558 chr20:47452577 G/A cg12307787 chr20:48099359 KCNB1 0.42 4.51 0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.587 rs10946813 chr6:26345141 A/G cg15659132 chr6:26577336 NA 0.52 5.36 0.43 3.98e-7 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.669 rs7974476 chr12:42542484 C/A cg19980929 chr12:42632907 YAF2 0.45 6.21 0.49 7.43e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs35306767 0.903 rs11253467 chr10:901244 A/G cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs2657888 0.529 rs71459376 chr12:56889139 C/G cg23002907 chr12:56915593 RBMS2 -0.37 -4.66 -0.39 7.9e-6 Adiponectin levels; TGCT cis rs7412746 0.658 rs12410394 chr1:150860186 G/A cg04414720 chr1:150670196 GOLPH3L 0.4 4.82 0.4 4.06e-6 Melanoma; TGCT cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg11890956 chr21:40555474 PSMG1 0.75 7.38 0.55 1.98e-11 Cognitive function; TGCT cis rs6463523 0.864 rs73047957 chr7:759373 A/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.74 10.68 0.69 2.83e-19 Subjective well-being; TGCT cis rs2239815 0.515 rs9625600 chr22:29244395 T/C cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT trans rs629535 0.862 rs2178955 chr8:70045303 C/T cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs9486719 0.947 rs12208556 chr6:96903486 C/T cg06623918 chr6:96969491 KIAA0776 -0.97 -9.2 -0.64 1.06e-15 Migraine;Coronary artery disease; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg01585852 chr22:24235823 MIF 0.22 4.69 0.39 7.13e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs854765 0.693 rs8079418 chr17:17924060 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.67 6.42 0.5 2.61e-9 Total body bone mineral density; TGCT cis rs7611238 0.560 rs6437373 chr3:195062395 A/G cg27323046 chr3:195102265 ACAP2 0.35 4.75 0.39 5.5e-6 Body mass index; TGCT cis rs2153535 0.580 rs9406174 chr6:8516764 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs4808199 0.947 rs754255 chr19:19578890 T/C cg03709012 chr19:19516395 GATAD2A 0.97 7.53 0.56 9.28e-12 Nonalcoholic fatty liver disease; TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg13808641 chr9:96006533 WNK2 0.49 7.13 0.54 7.4e-11 Breast cancer; TGCT cis rs868036 0.718 rs16951275 chr15:68077168 T/C cg05925327 chr15:68127851 NA -0.51 -4.94 -0.41 2.52e-6 Restless legs syndrome; TGCT cis rs9308731 1.000 rs2015454 chr2:111872148 A/G cg04202892 chr2:111875749 ACOXL 0.43 4.59 0.38 1.05e-5 Chronic lymphocytic leukemia; TGCT cis rs67460515 0.892 rs7610985 chr3:161062848 G/A cg03342759 chr3:160939853 NMD3 -0.51 -5.49 -0.44 2.14e-7 Parkinson's disease; TGCT cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg24675658 chr1:53192096 ZYG11B 0.86 11.3 0.71 8.54e-21 Monocyte count; TGCT cis rs7772486 0.782 rs7747576 chr6:146277827 C/T cg05347473 chr6:146136440 FBXO30 -0.54 -5.22 -0.42 7.38e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs36051895 0.623 rs10118434 chr9:5238460 A/G cg02405213 chr9:5042618 JAK2 -0.67 -8.15 -0.59 3.34e-13 Pediatric autoimmune diseases; TGCT cis rs8072100 1.000 rs3809868 chr17:45750596 G/A cg08085267 chr17:45401833 C17orf57 0.47 5.13 0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg09436375 chr6:42928200 GNMT -0.38 -4.9 -0.4 2.95e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs17376456 0.569 rs6881815 chr5:93105666 A/G cg21475434 chr5:93447410 FAM172A 0.6 4.9 0.4 2.92e-6 Diabetic retinopathy; TGCT cis rs9611519 0.565 rs8135524 chr22:41436442 T/C cg03806693 chr22:41940476 POLR3H -0.62 -5.7 -0.46 8.35e-8 Neuroticism; TGCT cis rs6901004 0.803 rs354544 chr6:111531159 T/C cg15721981 chr6:111408429 SLC16A10 -0.54 -4.71 -0.39 6.51e-6 Blood metabolite levels; TGCT cis rs35146811 0.700 rs7788301 chr7:99782753 C/G cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs6951245 1.000 rs11763020 chr7:1060288 C/T cg03188948 chr7:1209495 NA 0.56 4.61 0.38 9.68e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs7618501 0.573 rs7634917 chr3:50049299 T/G cg21659725 chr3:3221576 CRBN -0.76 -9.35 -0.64 4.6e-16 Intelligence (multi-trait analysis); TGCT cis rs4886920 0.601 rs4589520 chr15:78079434 C/G cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.37e-6 Neuroticism; TGCT cis rs12134245 0.776 rs61548854 chr1:92001536 C/T cg02896835 chr1:92012615 NA -0.27 -4.59 -0.38 1.08e-5 Breast cancer; TGCT cis rs4383453 0.539 rs3845913 chr3:123100606 T/A cg04890266 chr3:123102914 ADCY5 0.49 8.18 0.59 2.82e-13 Gestational age at birth (maternal effect); TGCT cis rs938554 0.657 rs9994216 chr4:9984541 G/T cg00071950 chr4:10020882 SLC2A9 0.49 4.65 0.39 8.39e-6 Blood metabolite levels; TGCT cis rs751728 0.643 rs12173787 chr6:33735471 G/C cg13859433 chr6:33739653 LEMD2 -0.33 -6.0 -0.47 1.99e-8 Crohn's disease; TGCT cis rs950169 0.922 rs4842939 chr15:84827966 C/T cg12863693 chr15:85201151 NMB -0.4 -4.52 -0.38 1.41e-5 Schizophrenia; TGCT cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs739496 0.843 rs642536 chr12:111997023 G/A cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs7264396 0.635 rs6060692 chr20:34517925 A/T cg04508476 chr20:34239394 CPNE1;RBM12 0.29 5.04 0.41 1.58e-6 Total cholesterol levels; TGCT cis rs9682041 0.935 rs11923053 chr3:170095281 T/C cg07589077 chr3:170072950 NA 0.3 4.54 0.38 1.3e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7264396 0.733 rs2425105 chr20:34312834 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.96e-7 Total cholesterol levels; TGCT cis rs7666738 0.830 rs1834645 chr4:98979593 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9640161 0.830 rs7800196 chr7:150061534 C/G cg10018233 chr7:150070692 REPIN1 0.37 5.89 0.47 3.39e-8 Blood protein levels;Circulating chemerin levels; TGCT cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs41271473 0.519 rs9660783 chr1:228886880 C/T cg18025438 chr1:228756789 NA 0.57 4.73 0.39 5.88e-6 Chronic lymphocytic leukemia; TGCT cis rs79839061 0.610 rs2279182 chr4:882625 T/G cg15843217 chr4:699224 PCGF3 -0.56 -4.52 -0.38 1.42e-5 Intelligence (multi-trait analysis); TGCT trans rs629535 0.814 rs674429 chr8:70069942 G/A cg21567404 chr3:27674614 NA 0.57 9.11 0.63 1.82e-15 Dupuytren's disease; TGCT cis rs7607369 0.637 rs3731866 chr2:219288899 C/T cg02176678 chr2:219576539 TTLL4 -0.5 -6.37 -0.5 3.41e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg12756686 chr19:29218302 NA 0.68 6.47 0.5 2e-9 Methadone dose in opioid dependence; TGCT cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg10546459 chr2:36825355 FEZ2 0.58 5.65 0.45 1.06e-7 Height; TGCT cis rs75059851 0.756 rs11223652 chr11:133841207 A/G cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs7465272 0.515 rs34087536 chr8:143720876 G/A cg10596483 chr8:143751796 JRK 0.53 5.12 0.42 1.14e-6 Bipolar disorder and schizophrenia; TGCT cis rs11783469 0.519 rs13250356 chr8:23359831 G/T cg00472375 chr8:23315376 ENTPD4 0.62 5.3 0.43 5.16e-7 Reticulocyte count; TGCT cis rs2224391 0.628 rs9504364 chr6:5256072 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.14 -0.48 1.01e-8 Height; TGCT cis rs4455778 0.659 rs7796789 chr7:49057671 C/T cg26309511 chr7:48887640 NA 0.44 5.12 0.42 1.13e-6 Lung cancer in never smokers; TGCT cis rs35883536 0.647 rs2783702 chr1:101040836 G/A cg10298815 chr1:101004474 GPR88 0.24 4.51 0.38 1.47e-5 Monocyte count; TGCT cis rs4631830 0.720 rs2611471 chr10:51503559 G/C cg10326726 chr10:51549505 MSMB -0.23 -4.68 -0.39 7.43e-6 Prostate-specific antigen levels; TGCT trans rs2624839 0.704 rs11919418 chr3:50233215 T/G cg21659725 chr3:3221576 CRBN 0.66 6.67 0.51 7.61e-10 Intelligence (multi-trait analysis); TGCT cis rs10751667 0.666 rs4074234 chr11:977715 C/G cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs12959333 0.772 rs12953612 chr18:33301227 G/A cg18885387 chr18:32820922 ZNF397 0.95 4.44 0.37 1.97e-5 Post bronchodilator FEV1; TGCT cis rs7565124 1.000 rs7608391 chr2:20261167 T/C cg00462460 chr2:20212509 MATN3 -0.43 -4.64 -0.38 8.69e-6 Major depressive disorder; TGCT cis rs346785 0.692 rs8074821 chr17:74293099 A/G cg09812376 chr17:74270190 QRICH2 -0.36 -5.34 -0.43 4.22e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs7845219 0.544 rs34293080 chr8:95908078 G/T cg13393036 chr8:95962371 TP53INP1 -0.45 -5.16 -0.42 9.7e-7 Type 2 diabetes; TGCT cis rs2070488 0.965 rs2284819 chr3:38557161 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.82 0.57 1.97e-12 Electrocardiographic conduction measures; TGCT cis rs826838 1.000 rs4768328 chr12:39129315 C/T cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT trans rs2469997 1.000 rs2470014 chr8:120360820 C/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs4819052 0.851 rs8133045 chr21:46658137 A/G cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs79387448 0.745 rs7601773 chr2:103120483 G/T cg09003973 chr2:102972529 NA 0.85 5.65 0.45 1.03e-7 Gut microbiota (bacterial taxa); TGCT cis rs651907 0.535 rs34743741 chr3:101532448 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.87 0.4 3.32e-6 Colorectal cancer; TGCT cis rs11690935 0.851 rs10930502 chr2:172890588 A/G cg13550731 chr2:172543902 DYNC1I2 -1.02 -9.72 -0.66 6.05e-17 Schizophrenia; TGCT cis rs7772486 0.597 rs6570732 chr6:146245151 G/A cg23711669 chr6:146136114 FBXO30 -0.74 -6.96 -0.53 1.75e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7086627 0.515 rs10887903 chr10:82210641 C/T cg00277334 chr10:82204260 NA -0.54 -8.44 -0.6 7.03e-14 Post bronchodilator FEV1; TGCT cis rs4851254 0.550 rs13402299 chr2:100659409 C/T cg07810366 chr2:100720526 AFF3 -0.46 -4.91 -0.4 2.76e-6 Intelligence (multi-trait analysis); TGCT cis rs10892173 0.935 rs7108548 chr11:117674072 A/T cg07621104 chr11:117668040 DSCAML1 0.47 4.81 0.4 4.31e-6 Myopia; TGCT cis rs4654899 0.897 rs611658 chr1:21089133 T/G cg01072550 chr1:21505969 NA -0.5 -8.03 -0.59 6.32e-13 Superior frontal gyrus grey matter volume; TGCT trans rs208520 0.874 rs208470 chr6:66916402 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -9.95 -0.67 1.64e-17 Exhaled nitric oxide output; TGCT cis rs6061231 0.597 rs624313 chr20:60927412 G/A cg24112000 chr20:60950667 NA 0.34 4.76 0.39 5.24e-6 Colorectal cancer; TGCT cis rs9611565 0.559 rs5751160 chr22:42175695 A/G cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs7666738 0.830 rs7672720 chr4:98938760 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7617773 0.746 rs6796343 chr3:48282021 C/A cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs259282 0.646 rs34182086 chr19:33125823 A/C cg26639809 chr19:33781782 NA 0.26 5.48 0.44 2.24e-7 Schizophrenia; TGCT cis rs11098499 0.754 rs7689729 chr4:120256192 A/G cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Corneal astigmatism; TGCT cis rs9534288 0.699 rs7139571 chr13:46662584 G/A cg15192986 chr13:46630673 CPB2 -0.51 -6.01 -0.47 1.92e-8 Blood protein levels; TGCT cis rs9486719 1.000 rs12213426 chr6:96896035 T/C cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7809950 0.817 rs2237678 chr7:107203265 T/G cg23024343 chr7:107201750 COG5 -0.47 -6.81 -0.52 3.74e-10 Coronary artery disease; TGCT trans rs853356 0.947 rs853383 chr6:14180705 C/T cg14262035 chr17:42019790 PPY 0.51 6.72 0.52 5.86e-10 Height; TGCT cis rs7727102 0.660 rs1909992 chr5:4711281 G/T cg13287621 chr5:3853654 NA 0.37 4.46 0.37 1.78e-5 Bipolar disorder and schizophrenia; TGCT cis rs1075232 1.000 rs9672214 chr15:31677775 A/T cg01030201 chr15:31746330 NA -1.1 -5.4 -0.44 3.27e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs11955175 1.000 rs113120818 chr5:40642896 T/A cg17351974 chr5:40835760 RPL37 0.76 4.75 0.39 5.46e-6 Bipolar disorder and schizophrenia; TGCT cis rs6964587 0.626 rs6951795 chr7:91543764 T/C cg17063962 chr7:91808500 NA -0.77 -7.32 -0.55 2.77e-11 Breast cancer; TGCT cis rs7810240 1.000 rs2888633 chr7:150083370 G/T cg24650120 chr7:150096722 NA -0.74 -9.86 -0.66 2.79e-17 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg02725872 chr8:58115012 NA -0.39 -4.74 -0.39 5.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs9457247 1.000 rs239935 chr6:167411788 G/A cg25258033 chr6:167368657 RNASET2 0.19 4.51 0.38 1.51e-5 Crohn's disease; TGCT cis rs3784262 0.512 rs4646571 chr15:58343137 T/C cg12031962 chr15:58353849 ALDH1A2 -0.51 -7.68 -0.57 4.14e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs8084125 0.832 rs62105179 chr18:74950858 A/G cg05528293 chr18:74961138 GALR1 0.52 5.18 0.42 8.65e-7 Obesity-related traits; TGCT cis rs7917772 0.636 rs2249845 chr10:104512095 A/G cg05855489 chr10:104503620 C10orf26 0.64 5.03 0.41 1.7e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs6089829 0.851 rs6122346 chr20:61661822 C/G cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 0.871 rs10504226 chr8:58159283 A/G cg24829409 chr8:58192753 C8orf71 -0.55 -5.06 -0.41 1.46e-6 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.677 rs678 chr3:52820981 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.58 5.42 0.44 3.02e-7 Bipolar disorder; TGCT trans rs2624839 0.639 rs2526389 chr3:50192826 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.75 7.43 0.56 1.56e-11 Intelligence (multi-trait analysis); TGCT cis rs17270561 0.525 rs12201678 chr6:25978993 C/T cg17042849 chr6:26104293 HIST1H4C -0.84 -5.82 -0.46 4.7e-8 Iron status biomarkers; TGCT cis rs5750830 0.649 rs5757659 chr22:39812409 A/C cg01416388 chr22:39784598 NA -0.65 -6.28 -0.49 5.1e-9 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.931 rs7435102 chr4:17571480 C/G cg18681998 chr4:17616180 MED28 0.94 9.51 0.65 1.93e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg03188948 chr7:1209495 NA 0.43 5.67 0.45 9.5e-8 Longevity;Endometriosis; TGCT cis rs10875746 0.903 rs12301339 chr12:48475233 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs79387448 0.655 rs3771167 chr2:102986188 A/G cg09003973 chr2:102972529 NA 1.39 11.37 0.71 5.75e-21 Gut microbiota (bacterial taxa); TGCT cis rs4523957 0.583 rs8077597 chr17:2043818 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7100689 0.754 rs1934695 chr10:82125230 T/C cg01528321 chr10:82214614 TSPAN14 0.88 8.48 0.61 5.61e-14 Post bronchodilator FEV1; TGCT cis rs9354352 0.935 rs9345749 chr6:66699892 G/T cg07460842 chr6:66804631 NA -0.57 -4.6 -0.38 1.02e-5 Initial pursuit acceleration in psychotic disorders; TGCT cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs651907 0.557 rs11720745 chr3:101441690 G/A cg12386194 chr3:101231763 SENP7 0.48 4.63 0.38 9.23e-6 Colorectal cancer; TGCT cis rs3806843 0.735 rs2530235 chr5:140072647 G/T cg19875535 chr5:140030758 IK -0.38 -6.33 -0.49 4.09e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6912958 0.781 rs9444512 chr6:88223397 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs9527 0.590 rs7917650 chr10:104937100 G/C cg15744005 chr10:104629667 AS3MT -0.4 -4.63 -0.38 9.04e-6 Arsenic metabolism; TGCT cis rs2836950 0.501 rs2836980 chr21:40687618 G/T cg06238570 chr21:40685208 BRWD1 -0.63 -6.44 -0.5 2.42e-9 Menarche (age at onset); TGCT cis rs56011263 0.687 rs4690292 chr4:703712 A/G cg17689763 chr4:710664 PCGF3 -0.24 -6.85 -0.52 3.02e-10 White blood cell count; TGCT cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs4689388 0.679 rs1046316 chr4:6304087 A/G cg14416269 chr4:6271139 WFS1 0.48 6.05 0.48 1.58e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12681287 0.640 rs13251006 chr8:87469105 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs968567 0.705 rs174575 chr11:61602003 C/G cg19610905 chr11:61596333 FADS2 -0.85 -7.4 -0.55 1.76e-11 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs9899728 0.539 rs57813751 chr17:73053512 C/T cg27626185 chr17:73056755 KCTD2 -0.92 -8.01 -0.58 7.17e-13 Alzheimer's disease or small vessel stroke; TGCT cis rs763121 0.962 rs6001193 chr22:39074737 A/G cg06022373 chr22:39101656 GTPBP1 0.73 7.14 0.54 7.12e-11 Menopause (age at onset); TGCT cis rs7959452 0.530 rs12811632 chr12:69755003 G/A cg11871910 chr12:69753446 YEATS4 0.83 8.9 0.62 5.55e-15 Blood protein levels; TGCT cis rs113601626 1 rs113601626 chr2:24239189 T/TCCTGGC cg08917208 chr2:24149416 ATAD2B 0.83 5.08 0.42 1.35e-6 Lymphocyte percentage of white cells; TGCT cis rs1215050 0.791 rs260893 chr4:98744785 A/C cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8177179 0.967 rs6439434 chr3:133450371 T/G cg16262614 chr3:133464971 TF 0.35 4.72 0.39 6.28e-6 Iron status biomarkers (transferrin levels); TGCT cis rs7223966 1.000 rs112143304 chr17:61822401 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 4.72 0.39 6.31e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2455799 0.559 rs6770404 chr3:15911428 G/C cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs1008375 0.606 rs6828925 chr4:17561139 C/T cg10189774 chr4:17578691 LAP3 0.6 5.65 0.45 1.05e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9859260 0.744 rs492349 chr3:195784192 G/A cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs2836950 0.501 rs2836983 chr21:40689336 G/A cg11890956 chr21:40555474 PSMG1 -0.66 -6.24 -0.49 6.47e-9 Menarche (age at onset); TGCT cis rs2180341 0.814 rs6919277 chr6:127738050 T/C cg27446573 chr6:127587934 RNF146 0.87 7.79 0.57 2.37e-12 Breast cancer; TGCT cis rs9443645 0.868 rs9443643 chr6:79798838 A/G cg05283184 chr6:79620031 NA -0.2 -4.45 -0.37 1.85e-5 Intelligence (multi-trait analysis); TGCT cis rs10214930 0.561 rs6961731 chr7:27925158 A/G cg05786569 chr7:27702416 HIBADH -0.73 -5.24 -0.43 6.74e-7 Hypospadias; TGCT cis rs8180040 0.966 rs62260711 chr3:47564491 G/C cg27129171 chr3:47204927 SETD2 -0.64 -7.34 -0.55 2.41e-11 Colorectal cancer; TGCT cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs11190604 1.000 rs2495742 chr10:102331364 C/T cg16342193 chr10:102329863 NA -0.42 -5.26 -0.43 5.99e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10507380 0.824 rs9512635 chr13:27920468 C/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs6674176 0.932 rs12410334 chr1:44442521 A/C cg12908607 chr1:44402522 ARTN -0.74 -8.47 -0.61 5.88e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6087990 0.806 rs910084 chr20:31379665 C/T cg13636640 chr20:31349939 DNMT3B 1.08 14.64 0.8 8.49e-29 Ulcerative colitis; TGCT cis rs4253772 0.637 rs9627350 chr22:46663017 A/G cg09491104 chr22:46646882 C22orf40 -0.67 -6.65 -0.51 8.56e-10 LDL cholesterol;Cholesterol, total; TGCT cis rs7829975 0.564 rs2921060 chr8:8317817 G/T cg06636001 chr8:8085503 FLJ10661 -0.77 -7.73 -0.57 3.17e-12 Mood instability; TGCT cis rs986417 1.000 rs1955686 chr14:61093560 C/T cg27398547 chr14:60952738 C14orf39 1.56 8.73 0.62 1.45e-14 Gut microbiota (bacterial taxa); TGCT cis rs1784581 0.851 rs1784591 chr6:162388893 C/G cg17173639 chr6:162384350 PARK2 -0.5 -9.35 -0.64 4.63e-16 Itch intensity from mosquito bite; TGCT trans rs11764590 0.950 rs11514731 chr7:2051503 C/G cg25206134 chr2:45395956 NA 1.0 7.57 0.56 7.46e-12 Neuroticism; TGCT cis rs7264396 0.790 rs6060582 chr20:34313297 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.29 5.25 0.43 6.33e-7 Total cholesterol levels; TGCT cis rs11190604 1.000 rs35106985 chr10:102307542 T/C cg23241863 chr10:102295624 HIF1AN 0.68 5.15 0.42 9.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12541335 0.507 rs9644047 chr8:22158670 T/A cg09517075 chr8:22133004 PIWIL2 0.23 4.45 0.37 1.91e-5 Hypertriglyceridemia; TGCT cis rs7590720 0.851 rs13006614 chr2:216876204 C/T cg12620499 chr2:216877984 MREG 0.9 10.93 0.7 6.95e-20 Alcohol dependence; TGCT cis rs7017914 0.967 rs35960437 chr8:71661960 C/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs4642101 0.793 rs13086170 chr3:12832604 G/C cg05775895 chr3:12838266 CAND2 0.78 8.9 0.62 5.77e-15 QRS complex (12-leadsum); TGCT cis rs7909074 0.966 rs879074 chr10:45400053 G/A cg05187965 chr10:45406764 TMEM72 -0.23 -4.88 -0.4 3.25e-6 Mean corpuscular volume; TGCT cis rs1799949 0.965 rs8176198 chr17:41230537 A/T cg05368731 chr17:41323189 NBR1 0.91 7.94 0.58 1.03e-12 Menopause (age at onset); TGCT cis rs7666738 0.606 rs10006454 chr4:99080361 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.61e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs4650994 0.935 rs4652306 chr1:178528206 T/C cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.54e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2197308 0.692 rs67352173 chr12:37906912 A/T cg26384229 chr12:38710491 ALG10B 0.85 7.82 0.57 1.94e-12 Morning vs. evening chronotype; TGCT cis rs7017914 0.934 rs35214141 chr8:71574564 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs6121246 0.559 rs6060933 chr20:30351903 C/T cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs7208859 0.623 rs7219712 chr17:29080570 G/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6746896 0.959 rs72809820 chr2:97360079 C/T cg26085987 chr2:97230376 NA 0.19 4.69 0.39 7.16e-6 Bipolar disorder; TGCT cis rs13217239 0.646 rs10946897 chr6:26995251 A/C cg02458000 chr6:26745757 NA 0.5 4.61 0.38 1e-5 Schizophrenia; TGCT cis rs6582630 0.563 rs923281 chr12:38590241 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.75 -0.39 5.62e-6 Drug-induced liver injury (flucloxacillin); TGCT trans rs629535 0.814 rs72654071 chr8:70079484 A/G cg21567404 chr3:27674614 NA -0.57 -8.99 -0.63 3.38e-15 Dupuytren's disease; TGCT trans rs4650994 0.967 rs6681043 chr1:178525957 A/G cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.37e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs860295 0.529 rs10908486 chr1:155978544 C/G cg05700447 chr1:155978627 NA -0.19 -4.75 -0.39 5.57e-6 Body mass index; TGCT cis rs6121246 0.529 rs6060145 chr20:30178631 T/C cg18721089 chr20:30220636 NA -0.63 -6.68 -0.51 7.29e-10 Mean corpuscular hemoglobin; TGCT trans rs4332037 0.539 rs4470910 chr7:2071723 C/T cg25206134 chr2:45395956 NA 0.98 7.42 0.55 1.63e-11 Bipolar disorder; TGCT cis rs7917772 0.582 rs10786691 chr10:104364652 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9818758 0.607 rs11552724 chr3:49156473 C/G cg00383909 chr3:49044727 WDR6 1.3 6.72 0.52 5.87e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs422249 0.512 rs99780 chr11:61596633 C/T cg01500311 chr11:61656094 FADS3 -0.32 -5.71 -0.46 8.04e-8 Trans fatty acid levels; TGCT cis rs2562456 0.652 rs4809145 chr19:21780709 A/C cg13978929 chr19:21580086 ZNF493 -0.58 -4.73 -0.39 6.04e-6 Pain; TGCT trans rs561341 0.609 rs739800 chr17:30190083 T/A cg20587970 chr11:113659929 NA 0.67 8.22 0.59 2.35e-13 Hip circumference adjusted for BMI; TGCT cis rs10109025 0.701 rs10101292 chr8:10856474 T/C cg21775007 chr8:11205619 TDH -0.49 -4.44 -0.37 1.94e-5 Joint mobility (Beighton score); TGCT cis rs2469997 1.000 rs2447172 chr8:120360863 A/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs250677 0.916 rs17109279 chr5:148416581 A/G cg18129178 chr5:148520854 ABLIM3 -0.4 -5.63 -0.45 1.17e-7 Breast cancer; TGCT cis rs10791097 0.667 rs12363163 chr11:130744509 A/G cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs13108904 0.604 rs11946375 chr4:1313488 T/C cg13395646 chr4:1353034 KIAA1530 -0.48 -6.95 -0.53 1.82e-10 Obesity-related traits; TGCT cis rs7113874 0.589 rs10840051 chr11:8475180 G/C cg14521421 chr11:8862019 ST5 0.28 4.44 0.37 1.94e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT trans rs1814175 0.935 rs7479914 chr11:49661351 T/C cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.74e-10 Height; TGCT cis rs9913156 0.793 rs4346260 chr17:4567215 A/G cg19197139 chr17:4613644 ARRB2 -0.87 -8.05 -0.59 5.79e-13 Lymphocyte counts; TGCT cis rs7647973 1.000 rs11710434 chr3:49346130 T/C cg05785598 chr3:49045655 WDR6 0.39 4.62 0.38 9.58e-6 Menarche (age at onset); TGCT trans rs6089829 0.926 rs6062395 chr20:61667904 A/G cg23505145 chr19:12996616 KLF1 0.77 7.97 0.58 8.9e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs4149423 1.000 rs4149420 chr2:108913090 G/T cg13968390 chr2:108904812 SULT1C2 -0.27 -5.16 -0.42 9.57e-7 Lobe size; TGCT cis rs7209700 0.600 rs7218632 chr17:45365153 A/G cg21624342 chr17:45890973 OSBPL7 0.16 4.46 0.37 1.85e-5 IgG glycosylation; TGCT cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg12310025 chr6:25882481 NA -0.59 -5.17 -0.42 8.92e-7 Intelligence (multi-trait analysis); TGCT cis rs739496 0.843 rs598710 chr12:111973141 A/C cg10833066 chr12:111807467 FAM109A 0.35 4.58 0.38 1.13e-5 Platelet count; TGCT cis rs7727544 0.654 rs4705849 chr5:131559199 T/A cg21474247 chr5:131268130 NA 0.31 4.49 0.37 1.59e-5 Blood metabolite levels; TGCT cis rs7681440 0.605 rs1372509 chr4:90817311 A/G cg10208370 chr4:90758469 SNCA -0.57 -5.41 -0.44 3.05e-7 Dementia with Lewy bodies; TGCT trans rs916888 0.821 rs199509 chr17:44858728 G/A cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2070488 0.965 rs6796845 chr3:38567771 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs295140 0.743 rs1729412 chr2:201083598 T/C cg04283868 chr2:201171347 SPATS2L -0.53 -5.25 -0.43 6.53e-7 QT interval; TGCT cis rs11650494 1.000 rs11650494 chr17:47345186 G/A cg08112188 chr17:47440006 ZNF652 1.06 5.44 0.44 2.68e-7 Prostate cancer; TGCT trans rs57221529 0.766 rs4957053 chr5:575927 T/C cg11887960 chr12:57824829 NA 1.1 9.44 0.65 2.89e-16 Lung disease severity in cystic fibrosis; TGCT cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg03806693 chr22:41940476 POLR3H 1.16 13.41 0.77 7.02e-26 Vitiligo; TGCT cis rs10540 0.841 rs35601764 chr11:532923 A/C cg03934478 chr11:495069 RNH1 0.32 4.55 0.38 1.28e-5 Body mass index; TGCT cis rs6988636 1.000 rs59601467 chr8:124193488 C/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs2204008 0.774 rs11520237 chr12:38266978 G/A cg13010199 chr12:38710504 ALG10B 0.61 4.67 0.39 7.69e-6 Bladder cancer; TGCT cis rs4273100 0.688 rs28760541 chr17:19172505 A/G cg03910582 chr17:19030146 GRAPL 0.51 6.15 0.48 9.7e-9 Schizophrenia; TGCT cis rs1801251 1.000 rs7587309 chr2:233705702 G/T cg25237894 chr2:233734115 C2orf82 -0.31 -5.49 -0.44 2.19e-7 Coronary artery disease; TGCT cis rs2153535 0.542 rs9505465 chr6:8510846 C/T cg07606381 chr6:8435919 SLC35B3 0.53 4.97 0.41 2.22e-6 Motion sickness; TGCT cis rs6087771 0.821 rs6058444 chr20:30315137 A/G cg13852791 chr20:30311386 BCL2L1 0.79 7.13 0.54 7.48e-11 Subcortical brain region volumes;Putamen volume; TGCT cis rs9611565 0.512 rs715498 chr22:42148467 G/A cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs7666738 0.830 rs34892904 chr4:98938097 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7178572 0.568 rs7176302 chr15:77671216 C/G cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg16414030 chr3:133502952 NA -0.5 -7.01 -0.53 1.39e-10 Iron status biomarkers; TGCT cis rs4319547 0.737 rs4758646 chr12:122946507 G/A cg23029597 chr12:123009494 RSRC2 -0.28 -4.52 -0.38 1.43e-5 Body mass index; TGCT cis rs9837602 0.529 rs793495 chr3:99507934 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.5 -5.66 -0.45 9.93e-8 Breast cancer; TGCT cis rs9611565 0.729 rs12165508 chr22:41819960 T/C cg06634786 chr22:41940651 POLR3H 0.81 7.71 0.57 3.43e-12 Vitiligo; TGCT cis rs79349575 0.729 rs62075824 chr17:46986679 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs6484504 0.532 rs10835756 chr11:31267622 C/T cg26647111 chr11:31128758 NA -0.35 -4.85 -0.4 3.58e-6 Red blood cell count; TGCT cis rs12519773 0.562 rs6557066 chr5:92499467 T/A cg04854328 chr5:92914828 FLJ42709 -0.3 -4.55 -0.38 1.24e-5 Migraine; TGCT cis rs6540559 0.611 rs926347 chr1:209965193 T/C cg22029157 chr1:209979665 IRF6 0.75 5.58 0.45 1.45e-7 Cleft lip with or without cleft palate; TGCT cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs2153535 0.580 rs1119690 chr6:8460660 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7552404 0.731 rs7523573 chr1:76372020 G/T cg22875332 chr1:76189707 ACADM 0.67 6.46 0.5 2.16e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9486719 1.000 rs4839837 chr6:96908706 G/A cg06623918 chr6:96969491 KIAA0776 0.96 9.44 0.65 2.83e-16 Migraine;Coronary artery disease; TGCT cis rs986417 0.901 rs9743622 chr14:61037163 A/T cg27398547 chr14:60952738 C14orf39 1.44 8.71 0.62 1.57e-14 Gut microbiota (bacterial taxa); TGCT cis rs2243480 1.000 rs1546059 chr7:65654709 C/A cg18252515 chr7:66147081 NA 1.22 7.33 0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg08736216 chr1:53307985 ZYG11A -0.3 -6.06 -0.48 1.48e-8 Monocyte count; TGCT cis rs17761864 0.675 rs72815344 chr17:2046947 T/C cg02171503 chr17:1588363 PRPF8 -0.5 -4.79 -0.4 4.7e-6 Esophageal cancer (squamous cell); TGCT cis rs9549367 0.826 rs1885688 chr13:113894236 G/T cg00898013 chr13:113819073 PROZ -0.43 -5.5 -0.44 2.11e-7 Platelet distribution width; TGCT cis rs6424115 0.830 rs4649124 chr1:24201357 A/G cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs28595532 0.920 rs56046676 chr4:119766733 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9913156 0.789 rs72824966 chr17:4596679 T/C cg00122941 chr17:4613640 ARRB2 0.88 7.63 0.57 5.46e-12 Lymphocyte counts; TGCT cis rs17384381 1.000 rs12743049 chr1:85897386 G/A cg16011679 chr1:85725395 C1orf52 0.8 6.44 0.5 2.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs739401 0.611 rs2301140 chr11:3022629 C/T cg25174290 chr11:3078921 CARS 0.47 4.6 0.38 1.04e-5 Longevity; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg00024416 chr22:24240387 NA -0.25 -4.9 -0.4 2.91e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs826838 0.967 rs11183622 chr12:38792849 T/C cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs950776 0.593 rs588765 chr15:78865425 T/C cg06917634 chr15:78832804 PSMA4 -0.65 -5.32 -0.43 4.65e-7 Sudden cardiac arrest; TGCT cis rs801193 1.000 rs62466793 chr7:66191517 G/A cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.1 -8.45 -0.6 6.56e-14 Platelet count; TGCT cis rs10782582 0.609 rs11584577 chr1:76242378 A/G cg10523679 chr1:76189770 ACADM -0.53 -4.98 -0.41 2.04e-6 Daytime sleep phenotypes; TGCT cis rs3733585 0.673 rs4235347 chr4:9951956 C/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.63 -0.51 9.3e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9346649 0.967 rs6907103 chr6:168490016 C/T cg02770688 chr6:168491649 NA -0.27 -5.08 -0.41 1.36e-6 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs6684514 0.961 rs10908501 chr1:156285513 G/T cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs644799 0.601 rs662168 chr11:95586982 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.67 6.59 0.51 1.13e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs902774 0.585 rs7399070 chr12:53355678 G/C cg07115879 chr12:52695515 KRT86 -0.47 -4.9 -0.4 2.89e-6 Prostate cancer; TGCT cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg23283495 chr1:209979779 IRF6 0.67 5.7 0.46 8.12e-8 Cleft lip with or without cleft palate; TGCT cis rs2046867 0.908 rs868336 chr3:72818165 A/C cg25664220 chr3:72788482 NA -0.53 -6.88 -0.53 2.65e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs13177918 0.750 rs59354956 chr5:149822020 G/A cg14059543 chr5:149831962 NA -0.71 -9.32 -0.64 5.69e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs597539 0.652 rs501799 chr11:68631240 G/T cg21963583 chr11:68658836 MRPL21 0.35 6.02 0.48 1.8e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs57221529 0.766 rs17497684 chr5:558307 T/C cg25482853 chr8:67687455 SGK3 1.2 10.16 0.67 5.25e-18 Lung disease severity in cystic fibrosis; TGCT cis rs778371 0.723 rs6704763 chr2:233592487 C/T cg08000102 chr2:233561755 GIGYF2 0.7 8.43 0.6 7.33e-14 Schizophrenia; TGCT cis rs7267979 0.844 rs6107027 chr20:25288632 A/G cg14121845 chr20:25566513 NINL 0.49 5.19 0.42 8.42e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3008870 0.755 rs2815360 chr1:67494458 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.22 0.59 2.32e-13 Lymphocyte percentage of white cells; TGCT cis rs9814567 0.964 rs9820425 chr3:134223018 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs561341 1.000 rs7210970 chr17:30262169 G/A cg20587970 chr11:113659929 NA -0.83 -7.97 -0.58 8.86e-13 Hip circumference adjusted for BMI; TGCT cis rs2549003 0.966 rs10213701 chr5:131824064 T/A cg21138405 chr5:131827807 IRF1 0.18 4.49 0.37 1.63e-5 Asthma (sex interaction); TGCT cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg21724239 chr8:58056113 NA 0.39 5.24 0.43 6.73e-7 Developmental language disorder (linguistic errors); TGCT cis rs6683383 1.000 rs17464408 chr1:203101073 T/A cg04395153 chr1:203052423 MYOG -0.29 -4.74 -0.39 5.76e-6 Asthma; TGCT cis rs79349575 0.756 rs2643361 chr17:46977462 T/G cg07967210 chr17:47022446 SNF8 0.43 6.08 0.48 1.4e-8 Type 2 diabetes; TGCT cis rs713587 0.563 rs7591460 chr2:25103967 A/C cg01884057 chr2:25150051 NA 0.31 5.77 0.46 5.94e-8 Body mass index in non-asthmatics; TGCT cis rs9894429 1.000 rs7209180 chr17:79581519 C/A cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs35160687 0.901 rs12478575 chr2:86535314 C/G cg12542933 chr2:85804724 VAMP8 0.41 4.9 0.4 2.97e-6 Night sleep phenotypes; TGCT cis rs6964587 0.743 rs33993294 chr7:91998655 A/C cg17063962 chr7:91808500 NA 0.83 8.04 0.59 6.09e-13 Breast cancer; TGCT cis rs61774743 0.681 rs10889959 chr1:41849735 T/C cg01193554 chr1:41846683 NA -0.44 -5.49 -0.44 2.13e-7 Intelligence (multi-trait analysis); TGCT cis rs780096 0.526 rs1647266 chr2:27693485 T/C cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT cis rs1371867 0.875 rs1619759 chr8:101337560 T/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.52 -0.51 1.64e-9 Atrioventricular conduction; TGCT cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg08280861 chr8:58055591 NA -0.39 -4.86 -0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs2228479 0.850 rs62054611 chr16:89817017 T/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7666738 0.546 rs34621463 chr4:98793357 G/C cg17366294 chr4:99064904 C4orf37 0.61 5.69 0.46 8.47e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg15659132 chr6:26577336 NA 0.54 5.34 0.43 4.37e-7 Schizophrenia; TGCT cis rs1371867 0.846 rs1788181 chr8:101334068 C/T cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs67311347 1.000 rs9874006 chr3:40471596 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs9916302 0.904 rs11654018 chr17:37703740 C/T cg07936489 chr17:37558343 FBXL20 0.64 5.02 0.41 1.79e-6 Glomerular filtration rate (creatinine); TGCT cis rs9926296 0.568 rs4420527 chr16:89814188 C/T cg21285383 chr16:89894308 SPIRE2 -0.43 -6.59 -0.51 1.14e-9 Vitiligo; TGCT cis rs35000415 0.938 rs17339836 chr7:128681062 C/T cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs11662586 0.517 rs11662894 chr18:77713591 G/A cg20368463 chr18:77673604 PQLC1 0.6 7.0 0.53 1.39e-10 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs9674544 0.740 rs11870560 chr17:47114033 T/C cg20966754 chr17:47091339 IGF2BP1 -0.46 -4.99 -0.41 2e-6 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs6840360 0.573 rs2407171 chr4:152256782 A/G cg17479576 chr4:152424074 FAM160A1 -0.44 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.647 rs12910820 chr15:77022825 T/C cg23625390 chr15:77176239 SCAPER -0.37 -4.67 -0.39 7.76e-6 Blood metabolite levels; TGCT cis rs116095464 0.558 rs9312957 chr5:202194 C/T cg22857025 chr5:266934 NA -0.35 -6.52 -0.51 1.63e-9 Breast cancer; TGCT cis rs8070740 0.898 rs9896735 chr17:5325808 G/T cg25236894 chr17:5323110 RPAIN;NUP88 -0.49 -4.88 -0.4 3.15e-6 Menopause (age at onset); TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg20007245 chr22:24372913 LOC391322 0.8 6.8 0.52 3.87e-10 S-phenylmercapturic acid levels in smokers; TGCT cis rs7617773 0.779 rs3731487 chr3:48229624 C/T cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs929354 0.742 rs2107863 chr7:156963731 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.81 7.35 0.55 2.39e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs28465658 chr4:99035866 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13191362 1.000 rs73035012 chr6:162997279 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7677751 0.806 rs7678144 chr4:55102425 T/C cg17187183 chr4:55093834 PDGFRA 0.56 7.13 0.54 7.37e-11 Corneal astigmatism; TGCT cis rs11690935 0.851 rs7573003 chr2:172741415 T/A cg13550731 chr2:172543902 DYNC1I2 -0.92 -8.46 -0.61 6.2e-14 Schizophrenia; TGCT cis rs9911578 1.000 rs2567905 chr17:56782297 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs2361718 0.500 rs8068856 chr17:78100731 A/G cg27614120 chr17:77386099 HRNBP3 0.29 5.02 0.41 1.72e-6 Yeast infection; TGCT cis rs7666738 0.830 rs1869082 chr4:98841254 T/A cg18180107 chr4:99064573 C4orf37 0.56 5.17 0.42 9.04e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9650657 0.740 rs34653170 chr8:10676542 G/T cg27411982 chr8:10470053 RP1L1 -0.23 -5.19 -0.42 8.48e-7 Neuroticism; TGCT cis rs4665809 0.878 rs4143538 chr2:26290178 A/C cg25036284 chr2:26402008 FAM59B -0.57 -5.04 -0.41 1.63e-6 Gut microbiome composition (summer); TGCT cis rs6121246 0.529 rs6088814 chr20:30218172 C/T cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.15 0.48 9.72e-9 Schizophrenia; TGCT cis rs4727027 0.704 rs13221837 chr7:148903597 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.64 0.38 8.83e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3096299 0.754 rs2965942 chr16:89510327 G/A cg08392591 chr16:89556376 ANKRD11 0.58 5.36 0.43 3.88e-7 Multiple myeloma (IgH translocation); TGCT cis rs34734847 1.000 rs34734847 chr12:121154221 T/C cg21892295 chr12:121157589 UNC119B -0.24 -5.71 -0.46 7.99e-8 Mean corpuscular volume; TGCT cis rs3820928 1.000 rs11692572 chr2:227774503 C/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.64 -0.38 8.58e-6 Pulmonary function; TGCT cis rs17826219 0.500 rs57005940 chr17:29066329 C/G cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Body mass index; TGCT cis rs2153535 0.580 rs9379216 chr6:8481235 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7635838 0.859 rs9869423 chr3:11459156 G/T cg00170343 chr3:11313890 ATG7 0.64 6.16 0.48 9.46e-9 HDL cholesterol; TGCT cis rs7666738 0.830 rs4323111 chr4:98952276 A/G cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1055129 0.516 rs7218498 chr17:73931847 C/G cg08125733 chr17:73851984 WBP2 0.57 5.24 0.43 6.72e-7 White matter hyperintensity burden; TGCT cis rs6840360 0.642 rs11932398 chr4:152397554 T/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs7246967 0.611 rs73030508 chr19:22826032 T/C cg05241461 chr19:22816980 ZNF492 0.67 4.51 0.38 1.47e-5 Bronchopulmonary dysplasia; TGCT cis rs910316 0.839 rs35977276 chr14:75637359 A/C cg08847533 chr14:75593920 NEK9 -0.93 -10.14 -0.67 5.65e-18 Height; TGCT cis rs7666738 0.830 rs10001479 chr4:98918764 A/G cg17366294 chr4:99064904 C4orf37 -0.72 -7.33 -0.55 2.64e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 1.000 rs17760953 chr2:99859863 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.87 -0.62 6.77e-15 Chronic sinus infection; TGCT cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg03303774 chr4:1407052 NA 0.32 4.88 0.4 3.16e-6 Obesity-related traits; TGCT cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg06640241 chr16:89574553 SPG7 0.72 7.85 0.58 1.68e-12 Multiple myeloma (IgH translocation); TGCT cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT trans rs797680 1.000 rs797680 chr1:93716974 G/T cg27528825 chr2:159282178 CCDC148 0.36 6.95 0.53 1.82e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11785400 0.793 rs4581034 chr8:143736968 G/A cg24634471 chr8:143751801 JRK 0.55 5.52 0.44 1.87e-7 Schizophrenia; TGCT cis rs9443645 0.901 rs9343860 chr6:79739010 G/A cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs9894429 0.634 rs9709130 chr17:79583948 C/T cg18240062 chr17:79603768 NPLOC4 0.56 4.92 0.4 2.67e-6 Eye color traits; TGCT cis rs7666738 0.791 rs10010438 chr4:99022177 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs60871478 0.947 rs4074610 chr7:791755 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.45 4.49 0.37 1.6e-5 Cerebrospinal P-tau181p levels; TGCT cis rs7914558 0.932 rs4307650 chr10:104959852 C/A cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.67e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1023500 0.505 rs134889 chr22:42674350 A/T cg05082376 chr22:42548792 NA -0.21 -4.47 -0.37 1.76e-5 Schizophrenia; TGCT cis rs8192284 1.000 rs2228145 chr1:154426970 A/C cg00791854 chr1:154392070 IL6R 0.29 4.64 0.38 8.85e-6 Fibrinogen;C-reactive protein;Fibrinogen levels; TGCT cis rs2836950 0.502 rs2150411 chr21:40574552 G/T cg17971929 chr21:40555470 PSMG1 -0.51 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT cis rs10986311 0.775 rs3780198 chr9:127175598 G/C cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -4.87 -0.4 3.37e-6 Vitiligo; TGCT cis rs13242816 1.000 rs62468976 chr7:116126891 C/G cg16553024 chr7:116138462 CAV2 -0.43 -4.88 -0.4 3.26e-6 P wave duration; TGCT trans rs1814175 0.717 rs11040450 chr11:49650638 G/A cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs9811920 0.638 rs10936008 chr3:99686665 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.87 -0.52 2.82e-10 Axial length; TGCT cis rs6671200 1.000 rs10747468 chr1:95686291 C/T cg26537280 chr1:95699037 RWDD3 0.64 5.39 0.44 3.37e-7 Stearic acid (18:0) levels; TGCT cis rs7172809 0.599 rs2864840 chr15:77732001 C/T cg22256960 chr15:77711686 NA -0.51 -4.87 -0.4 3.32e-6 Glucose homeostasis traits; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg12419862 chr22:24373484 LOC391322 -0.85 -9.99 -0.67 1.3e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9303401 0.659 rs34275691 chr17:56736640 A/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7666738 0.830 rs4699600 chr4:99019429 C/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs644799 0.965 rs11021313 chr11:95506907 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.46 0.6 6.27e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg25151919 chr3:44754333 ZNF502 -0.47 -5.46 -0.44 2.49e-7 Depressive symptoms; TGCT cis rs7267979 1.000 rs6138572 chr20:25435934 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854765 0.583 rs7207043 chr17:17819188 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.69 0.57 3.91e-12 Total body bone mineral density; TGCT cis rs829661 0.947 rs829665 chr2:30724701 T/A cg17749961 chr2:30669863 LCLAT1 1.13 8.03 0.58 6.45e-13 Midgestational circulating levels of PBDEs (fetal genetic effect); TGCT cis rs4072705 0.586 rs7023736 chr9:127247946 G/A cg13476313 chr9:127244764 NR5A1 0.3 5.1 0.42 1.25e-6 Menarche (age at onset); TGCT cis rs6964587 1.000 rs10263309 chr7:91645265 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs7119 0.700 rs4886519 chr15:77893885 A/G cg27398640 chr15:77910606 LINGO1 0.33 6.83 0.52 3.3e-10 Type 2 diabetes; TGCT cis rs9359856 0.510 rs74437492 chr6:90338728 A/G cg13799429 chr6:90582589 CASP8AP2 -0.43 -4.44 -0.37 1.96e-5 Bipolar disorder; TGCT cis rs1552244 0.572 rs41464050 chr3:10158393 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.44 -5.79 -0.46 5.42e-8 Alzheimer's disease; TGCT cis rs72781680 0.784 rs12616678 chr2:24181159 G/T cg08917208 chr2:24149416 ATAD2B 0.72 4.5 0.37 1.56e-5 Lymphocyte counts; TGCT cis rs4494114 1.000 rs12127091 chr1:39339449 C/T cg25970120 chr1:39325951 RRAGC -0.6 -6.23 -0.49 6.58e-9 Blood protein levels; TGCT cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg19774624 chr17:42201019 HDAC5 -0.88 -11.23 -0.71 1.27e-20 Total body bone mineral density; TGCT cis rs5750830 0.649 rs5750811 chr22:39793066 G/T cg02038168 chr22:39784481 NA 0.68 5.75 0.46 6.42e-8 Intelligence (multi-trait analysis); TGCT cis rs9952991 0.941 rs2542149 chr18:12779018 G/A cg23598886 chr18:12777645 NA 0.62 5.9 0.47 3.25e-8 Inflammatory skin disease; TGCT cis rs10751667 0.580 rs11246363 chr11:971667 T/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.66e-13 Alzheimer's disease (late onset); TGCT cis rs1865760 0.516 rs9393684 chr6:26075531 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.38 0.55 2.03e-11 Height; TGCT cis rs3796352 1.000 rs3097417 chr3:53088601 C/G cg15956490 chr3:53032818 SFMBT1 -0.55 -6.56 -0.51 1.32e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9325144 0.600 rs12297194 chr12:38735803 A/G cg13010199 chr12:38710504 ALG10B -0.53 -4.83 -0.4 4.02e-6 Morning vs. evening chronotype; TGCT cis rs3806843 0.518 rs2563310 chr5:140015741 A/G cg19875535 chr5:140030758 IK -0.33 -5.26 -0.43 6.05e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs877282 1.000 rs11253367 chr10:773389 G/A cg22713356 chr15:30763199 NA 1.15 10.1 0.67 7.07e-18 Uric acid levels; TGCT cis rs12477438 0.765 rs6754843 chr2:99680485 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg17775962 chr7:1200435 ZFAND2A 0.28 4.88 0.4 3.13e-6 Longevity;Endometriosis; TGCT cis rs6554196 0.606 rs7663318 chr4:55538880 T/C cg26039058 chr4:54931064 CHIC2 0.54 4.62 0.38 9.28e-6 Monocyte count; TGCT cis rs8028182 0.577 rs8023268 chr15:75814672 A/T cg20655648 chr15:75932815 IMP3 0.59 4.62 0.38 9.55e-6 Sudden cardiac arrest; TGCT cis rs968567 0.501 rs174553 chr11:61575158 A/G cg01500311 chr11:61656094 FADS3 -0.3 -5.25 -0.43 6.42e-7 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs713587 0.935 rs11676272 chr2:25141538 A/G cg15423357 chr2:25149977 NA 0.64 6.83 0.52 3.41e-10 Body mass index in non-asthmatics; TGCT cis rs2075371 0.932 rs2241333 chr7:133970750 C/T cg11752832 chr7:134001865 SLC35B4 0.66 6.11 0.48 1.19e-8 Mean platelet volume; TGCT cis rs2178146 0.535 rs17181663 chr16:86449076 C/T cg11165158 chr16:86613094 FOXL1 0.34 4.59 0.38 1.05e-5 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT trans rs208520 0.690 rs12194057 chr6:66745616 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg11115673 chr10:50224628 C10orf72 -0.83 -7.11 -0.54 8.21e-11 Follicular lymphoma; TGCT cis rs8010715 1.000 rs2236352 chr14:24610733 T/C cg23112188 chr14:24563095 PCK2 -0.41 -4.84 -0.4 3.8e-6 IgG glycosylation; TGCT cis rs1008375 0.931 rs10939733 chr4:17570658 T/C cg18681998 chr4:17616180 MED28 0.94 9.51 0.65 1.93e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs477895 0.713 rs3802933 chr11:63988102 C/T cg23719950 chr11:63933701 MACROD1 -0.72 -6.04 -0.48 1.63e-8 Mean platelet volume; TGCT cis rs208520 0.609 rs208436 chr6:66897470 G/A cg07460842 chr6:66804631 NA -0.67 -6.69 -0.52 6.82e-10 Exhaled nitric oxide output; TGCT cis rs67478160 0.595 rs12889993 chr14:104274294 A/G cg26031613 chr14:104095156 KLC1 -0.64 -6.57 -0.51 1.23e-9 Schizophrenia; TGCT cis rs858239 0.511 rs10256996 chr7:23145295 G/T cg05602783 chr7:23145260 KLHL7 0.7 6.76 0.52 4.71e-10 Cerebrospinal fluid biomarker levels; TGCT cis rs769267 0.895 rs2916073 chr19:19528324 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.61 5.06 0.41 1.45e-6 Tonsillectomy; TGCT cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg11644478 chr21:40555479 PSMG1 0.98 10.28 0.68 2.68e-18 Cognitive function; TGCT cis rs763121 0.853 rs5750673 chr22:39110124 G/A cg06022373 chr22:39101656 GTPBP1 0.71 6.59 0.51 1.14e-9 Menopause (age at onset); TGCT cis rs2120019 1.000 rs7167285 chr15:75368769 A/G cg17294928 chr15:75287854 SCAMP5 -0.85 -6.5 -0.5 1.78e-9 Blood trace element (Zn levels); TGCT cis rs2033711 0.783 rs8113810 chr19:58932106 A/G cg04608855 chr19:58913158 NA 0.57 5.66 0.45 1.02e-7 Uric acid clearance; TGCT cis rs3806843 0.576 rs251376 chr5:140253689 A/G cg09824255 chr5:140014002 CD14 -0.26 -4.64 -0.38 8.87e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7945705 0.967 rs10769970 chr11:8917937 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.19 0.42 8.23e-7 Hemoglobin concentration; TGCT cis rs9611565 0.512 rs139560 chr22:42194962 A/G cg13695892 chr22:41940480 POLR3H -0.8 -7.6 -0.56 6.36e-12 Vitiligo; TGCT cis rs10858047 0.883 rs6537839 chr1:115188908 G/T cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs5769765 0.837 rs4824110 chr22:50271631 T/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs2692947 0.644 rs3821051 chr2:96912787 A/G cg22654517 chr2:96458247 NA -0.21 -4.85 -0.4 3.61e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs910316 1.000 rs3742778 chr14:75538217 A/C cg08847533 chr14:75593920 NEK9 -0.97 -10.82 -0.7 1.28e-19 Height; TGCT trans rs7819412 0.775 rs4841489 chr8:10936811 A/G cg15556689 chr8:8085844 FLJ10661 -0.84 -8.16 -0.59 3.26e-13 Triglycerides; TGCT cis rs7208859 0.623 rs73267858 chr17:29059737 A/G cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs10746514 0.833 rs11122428 chr1:232261417 A/G cg09506761 chr1:232265262 NA -0.5 -5.17 -0.42 9.3e-7 Response to statin therapy; TGCT cis rs748404 0.578 rs576557 chr15:43597737 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.56 0.38 1.19e-5 Lung cancer; TGCT cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg20302342 chr1:156215951 PAQR6 0.36 5.38 0.44 3.56e-7 Tonsillectomy; TGCT cis rs7432375 0.804 rs6764567 chr3:136425514 A/C cg12473912 chr3:136751656 NA -0.36 -5.06 -0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT trans rs11785693 0.909 rs62489558 chr8:4968620 G/A cg21607066 chr6:79787807 PHIP 0.92 6.84 0.52 3.18e-10 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs13082711 0.522 rs653886 chr3:27343549 C/T cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs9467711 1.000 rs9467701 chr6:26312170 G/C cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2658782 0.547 rs4344448 chr11:93047047 T/C cg15737290 chr11:93063684 CCDC67 1.0 10.37 0.68 1.58e-18 Pulmonary function decline; TGCT cis rs908922 0.651 rs4845444 chr1:152530125 G/A cg20991723 chr1:152506922 NA 0.44 5.98 0.47 2.2e-8 Hair morphology; TGCT cis rs4788815 0.552 rs7187129 chr16:71861444 T/C cg06353428 chr16:71660113 MARVELD3 0.81 7.32 0.55 2.79e-11 Metabolite levels; TGCT cis rs12135894 0.562 rs6688969 chr1:3743391 C/T cg10555106 chr1:3691387 LOC388588 0.31 4.88 0.4 3.21e-6 Mean corpuscular volume; TGCT cis rs7647973 0.731 rs13084037 chr3:49214066 G/A cg05785598 chr3:49045655 WDR6 0.44 5.04 0.41 1.6e-6 Menarche (age at onset); TGCT cis rs6740322 0.843 rs6727237 chr2:43562000 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.32 -0.49 4.21e-9 Coronary artery disease; TGCT cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 2.93e-27 Menopause (age at onset); TGCT cis rs10875595 0.723 rs62378371 chr5:140680211 G/A cg24830062 chr5:140700576 TAF7 -0.69 -5.38 -0.43 3.6e-7 Pulmonary function decline; TGCT cis rs500492 0.508 rs449566 chr16:1074581 C/T cg01366354 chr16:1075121 NA 0.36 5.23 0.43 6.99e-7 Polycystic ovary syndrome; TGCT cis rs35306767 0.953 rs11253520 chr10:975961 C/G cg18964960 chr10:1102726 WDR37 -0.53 -4.63 -0.38 9e-6 Eosinophil percentage of granulocytes; TGCT cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg04013166 chr16:89971882 TCF25 0.33 4.86 0.4 3.47e-6 Skin colour saturation; TGCT cis rs10927875 0.722 rs1763606 chr1:16338282 A/G cg21385522 chr1:16154831 NA 0.6 6.38 0.5 3.14e-9 Dilated cardiomyopathy; TGCT cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg23708337 chr7:1209742 NA 0.56 5.09 0.42 1.31e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs806215 0.547 rs9791922 chr7:127559133 T/C cg11539674 chr7:127291444 SND1 -0.35 -4.52 -0.38 1.43e-5 Type 2 diabetes; TGCT cis rs8077577 0.945 rs8065026 chr17:18046290 A/G cg09161412 chr17:18057145 MYO15A -0.63 -5.2 -0.42 7.87e-7 Obesity-related traits; TGCT cis rs2982552 0.787 rs11155810 chr6:152056081 T/C cg22157087 chr6:152012887 ESR1 0.21 5.17 0.42 8.93e-7 Bone properties (heel); TGCT cis rs6951245 0.554 rs76243429 chr7:1152543 C/T cg23708337 chr7:1209742 NA 0.44 4.97 0.41 2.13e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs877282 0.891 rs12767043 chr10:797943 C/T cg22713356 chr15:30763199 NA 1.16 10.18 0.67 4.53e-18 Uric acid levels; TGCT cis rs9913156 0.789 rs72824966 chr17:4596679 T/C cg19197139 chr17:4613644 ARRB2 0.83 7.74 0.57 3.03e-12 Lymphocyte counts; TGCT cis rs933688 0.877 rs1477349 chr5:90707773 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.06 0.59 5.53e-13 Smoking behavior; TGCT cis rs709400 0.930 rs10149249 chr14:104047757 C/T cg26031613 chr14:104095156 KLC1 1.14 15.35 0.81 1.87e-30 Body mass index; TGCT cis rs9926296 0.605 rs886952 chr16:89836781 G/A cg26513180 chr16:89883248 FANCA 1.03 14.55 0.79 1.35e-28 Vitiligo; TGCT cis rs4819052 0.851 rs4819041 chr21:46659955 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 6.26 0.49 5.64e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11122272 0.735 rs2739509 chr1:231526765 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.3 -0.49 4.72e-9 Hemoglobin concentration; TGCT cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg14262678 chr6:151773367 RMND1;C6orf211 -0.53 -5.06 -0.41 1.48e-6 Menarche (age at onset); TGCT cis rs12484776 0.786 rs73165039 chr22:40535152 A/G cg07138101 chr22:40742427 ADSL 0.61 4.65 0.39 8.24e-6 Uterine fibroids; TGCT cis rs17133449 0.718 rs7905751 chr10:4752837 A/T cg04530666 chr10:3759553 NA -0.31 -5.22 -0.42 7.34e-7 Major depressive disorder; TGCT cis rs6867032 1.000 rs6867032 chr5:2015103 G/T cg26168224 chr5:2018326 NA -0.44 -8.11 -0.59 4.08e-13 Gut microbiome composition (winter); TGCT cis rs9467711 0.720 rs35627490 chr6:26462104 C/T cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs806795 0.605 rs809871 chr6:26256526 C/G cg00631329 chr6:26305371 NA 0.34 5.32 0.43 4.59e-7 Mosquito bite size; TGCT cis rs10193935 0.792 rs72794590 chr2:42378392 G/A cg27598129 chr2:42591480 NA -0.42 -5.44 -0.44 2.74e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9297145 0.585 rs13235218 chr7:98785080 C/T cg05967295 chr7:98741636 SMURF1 -0.68 -8.29 -0.6 1.54e-13 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs7246657 0.882 rs6508716 chr19:37819010 T/C cg18154014 chr19:37997991 ZNF793 0.74 5.08 0.42 1.34e-6 Coronary artery calcification; TGCT cis rs1552244 0.554 rs6762397 chr3:10007840 C/T cg00149659 chr3:10157352 C3orf10 0.63 4.65 0.39 8.35e-6 Alzheimer's disease; TGCT cis rs6087771 0.682 rs2038397 chr20:30217759 A/G cg21427119 chr20:30132790 HM13 -0.3 -5.11 -0.42 1.18e-6 Subcortical brain region volumes;Putamen volume; TGCT cis rs6570726 0.967 rs441364 chr6:145853662 G/C cg05347473 chr6:146136440 FBXO30 0.49 4.45 0.37 1.88e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2637266 0.905 rs1907313 chr10:78338072 A/G cg18941641 chr10:78392320 NA 0.42 5.45 0.44 2.62e-7 Pulmonary function; TGCT cis rs1577917 1.000 rs7747824 chr6:86647106 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs700651 0.752 rs1850631 chr2:198829468 T/G cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Intracranial aneurysm; TGCT cis rs1215050 0.791 rs6838628 chr4:98809574 A/G cg17366294 chr4:99064904 C4orf37 0.51 5.55 0.45 1.67e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs40363 1.000 rs28401 chr16:3515354 C/G cg22508957 chr16:3507546 NAT15 0.57 5.15 0.42 1.01e-6 Tuberculosis; TGCT cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs9611519 0.929 rs2064560 chr22:41530040 A/G cg13695892 chr22:41940480 POLR3H -0.51 -4.48 -0.37 1.69e-5 Neuroticism; TGCT cis rs453301 0.658 rs6983877 chr8:8904639 T/C cg06636001 chr8:8085503 FLJ10661 -0.69 -5.59 -0.45 1.37e-7 Joint mobility (Beighton score); TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg17178900 chr1:205818956 PM20D1 0.56 7.03 0.53 1.2e-10 Menarche (age at onset); TGCT cis rs2688608 0.592 rs10762559 chr10:75486453 G/C cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.93e-8 Inflammatory bowel disease; TGCT cis rs2013441 1.000 rs2703816 chr17:20118887 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs10858047 0.883 rs72698011 chr1:115093654 T/C cg12756093 chr1:115239321 AMPD1 0.45 4.63 0.38 9.24e-6 Autism; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg21672276 chr3:44754072 ZNF502 -0.55 -6.37 -0.5 3.41e-9 Depressive symptoms; TGCT cis rs854765 0.647 rs721669 chr17:18005073 A/G cg04398451 chr17:18023971 MYO15A -0.37 -6.46 -0.5 2.14e-9 Total body bone mineral density; TGCT cis rs9457247 0.967 rs1794696 chr6:167396174 T/C cg25258033 chr6:167368657 RNASET2 0.2 4.82 0.4 4.09e-6 Crohn's disease; TGCT cis rs4074961 0.527 rs10908355 chr1:38035286 G/T cg17933807 chr1:38061675 GNL2 1.05 15.81 0.82 1.69e-31 Axial length; TGCT cis rs9325144 0.647 rs11168741 chr12:38989120 C/T cg10518543 chr12:38710700 ALG10B -0.48 -4.57 -0.38 1.17e-5 Morning vs. evening chronotype; TGCT cis rs3751972 0.697 rs4063521 chr17:26220355 G/T cg02948944 chr17:26242737 NA 0.33 4.79 0.4 4.63e-6 Fractional exhaled nitric oxide (childhood); TGCT cis rs8072100 0.688 rs7221224 chr17:45419061 T/G cg08085267 chr17:45401833 C17orf57 0.46 5.05 0.41 1.51e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4850410 0.626 rs7582411 chr2:197912886 A/G cg19149314 chr2:197065128 HECW2 0.22 4.53 0.38 1.37e-5 Interferon alpha levels in systemic lupus erythematosus; TGCT cis rs2289583 0.517 rs2004278 chr15:75264363 C/T cg10253484 chr15:75165896 SCAMP2 0.56 5.0 0.41 1.87e-6 Systemic lupus erythematosus; TGCT trans rs1005277 0.579 rs2505241 chr10:38442421 T/C cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.72e-21 Extrinsic epigenetic age acceleration; TGCT cis rs7681440 0.728 rs974711 chr4:90737327 G/A cg14346243 chr4:90757452 SNCA -0.54 -5.1 -0.42 1.24e-6 Dementia with Lewy bodies; TGCT cis rs3960554 0.808 rs11983987 chr7:75657850 A/G cg17325771 chr7:75508891 RHBDD2 -0.51 -4.74 -0.39 5.87e-6 Eotaxin levels; TGCT cis rs6540559 0.673 rs17015330 chr1:210012795 T/G cg22029157 chr1:209979665 IRF6 0.71 5.09 0.42 1.3e-6 Cleft lip with or without cleft palate; TGCT cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs7542091 0.813 rs2049999 chr1:210031331 A/G cg23283495 chr1:209979779 IRF6 0.47 4.76 0.39 5.32e-6 Monobrow; TGCT cis rs2404602 0.684 rs62026898 chr15:76944371 C/A cg23625390 chr15:77176239 SCAPER -0.36 -4.62 -0.38 9.3e-6 Blood metabolite levels; TGCT cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2439831 1.000 rs527921 chr15:43770416 G/T cg02155558 chr15:43621948 ADAL;LCMT2 -1.0 -7.35 -0.55 2.38e-11 Lung cancer in ever smokers; TGCT cis rs7647973 1.000 rs7647973 chr3:49510931 G/A cg06212747 chr3:49208901 KLHDC8B -0.59 -4.67 -0.39 7.6e-6 Menarche (age at onset); TGCT cis rs72781680 0.898 rs72782117 chr2:24026921 G/A cg08917208 chr2:24149416 ATAD2B 0.93 5.84 0.46 4.22e-8 Lymphocyte counts; TGCT cis rs1799949 0.965 rs799908 chr17:41278916 A/G cg05368731 chr17:41323189 NBR1 1.07 12.07 0.73 1.17e-22 Menopause (age at onset); TGCT cis rs6951245 0.872 rs75280240 chr7:1058511 C/T cg18402987 chr7:1209562 NA 0.65 5.32 0.43 4.65e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs67478160 0.643 rs11624184 chr14:104240998 A/G cg26031613 chr14:104095156 KLC1 -0.61 -6.28 -0.49 5.19e-9 Schizophrenia; TGCT cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg03517284 chr6:25882590 NA -0.52 -5.28 -0.43 5.67e-7 Blood metabolite levels; TGCT cis rs6570726 0.764 rs9399553 chr6:145873664 A/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9486719 0.948 rs2472881 chr6:96862562 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs11931598 0.513 rs3857170 chr4:7003366 A/T cg26116260 chr4:7069785 GRPEL1 0.59 5.48 0.44 2.32e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs4319547 0.956 rs7397990 chr12:123119472 T/C cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.32 -0.43 4.62e-7 Body mass index; TGCT cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.47 0.65 2.42e-16 Cognitive function; TGCT cis rs6906287 0.625 rs7764280 chr6:118692514 A/G cg21191810 chr6:118973309 C6orf204 0.26 4.47 0.37 1.74e-5 Electrocardiographic conduction measures; TGCT cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs9443189 0.570 rs485906 chr6:76300550 A/C cg01950844 chr6:76311363 SENP6 0.95 5.98 0.47 2.16e-8 Prostate cancer; TGCT cis rs1372520 0.577 rs1811443 chr4:90747883 G/C cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs1008375 0.932 rs6841784 chr4:17626418 G/A cg18681998 chr4:17616180 MED28 1.0 10.26 0.68 2.93e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7044106 0.762 rs10818471 chr9:123394045 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.47 5.08 0.41 1.37e-6 Hip circumference adjusted for BMI; TGCT cis rs1949733 0.701 rs940134 chr4:8454870 C/T cg13073564 chr4:8508604 NA -0.42 -4.61 -0.38 9.77e-6 Response to antineoplastic agents; TGCT cis rs35374984 0.920 rs7897595 chr10:30234930 C/T cg22629853 chr10:30638455 MTPAP -0.58 -5.36 -0.43 3.99e-7 Emphysema distribution in smoking; TGCT cis rs12950390 0.853 rs17773010 chr17:45858297 C/T cg24803719 chr17:45855879 NA -0.5 -5.12 -0.42 1.15e-6 IgG glycosylation; TGCT cis rs3008870 0.755 rs10749766 chr1:67376921 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.46 0.61 6.24e-14 Lymphocyte percentage of white cells; TGCT cis rs28595532 0.920 rs55901549 chr4:119770172 T/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs9527 0.615 rs7899622 chr10:104727333 C/T cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg13397359 chr6:42928475 GNMT 0.82 7.87 0.58 1.5e-12 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4727027 0.901 rs11760293 chr7:148811725 A/G cg23583168 chr7:148888333 NA -0.72 -9.16 -0.64 1.34e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs950027 0.787 rs1547487 chr15:45723983 A/G cg14582100 chr15:45693742 SPATA5L1 0.39 4.89 0.4 3.01e-6 Response to fenofibrate (adiponectin levels); TGCT cis rs981844 0.857 rs62325141 chr4:154716407 A/G cg14289246 chr4:154710475 SFRP2 1.05 8.88 0.62 6.23e-15 Response to statins (LDL cholesterol change); TGCT cis rs6500602 0.653 rs4786488 chr16:4442527 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.28 4.51 0.38 1.49e-5 Schizophrenia; TGCT cis rs3125734 0.571 rs7100401 chr10:64024417 C/G cg05499367 chr10:63213510 TMEM26 -0.33 -4.47 -0.37 1.77e-5 Rheumatoid arthritis; TGCT cis rs7605378 1.000 rs7577763 chr2:200681753 C/T cg23649088 chr2:200775458 C2orf69 0.35 5.83 0.46 4.53e-8 Osteoporosis; TGCT cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg09904177 chr6:26538194 HMGN4 0.67 6.32 0.49 4.25e-9 Intelligence (multi-trait analysis); TGCT cis rs4819852 0.958 rs2238786 chr22:19975444 A/G cg07821417 chr22:19972146 ARVCF 0.19 4.79 0.4 4.7e-6 Pulse pressure; TGCT cis rs4654899 0.571 rs34530426 chr1:21085204 C/T cg01072550 chr1:21505969 NA -0.54 -8.85 -0.62 7.34e-15 Superior frontal gyrus grey matter volume; TGCT cis rs7824557 0.564 rs13260727 chr8:11232860 A/G cg21775007 chr8:11205619 TDH 0.52 4.94 0.41 2.5e-6 Retinal vascular caliber; TGCT cis rs9467711 0.516 rs1324088 chr6:25841122 C/T cg03517284 chr6:25882590 NA -0.7 -4.65 -0.39 8.22e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1497406 0.744 rs12057175 chr1:16508375 A/G cg20430773 chr1:16534157 ARHGEF19 0.54 6.27 0.49 5.36e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1629083 0.935 rs1715453 chr11:118125077 T/C cg16594165 chr11:118135105 MPZL2 -0.33 -4.62 -0.38 9.6e-6 Lung cancer; TGCT cis rs6674176 0.660 rs3791112 chr1:44379248 T/G cg13606994 chr1:44402422 ARTN -0.49 -5.4 -0.44 3.22e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1799899 1.000 rs1799899 chr3:133475812 G/A cg18342939 chr3:134203408 ANAPC13;CEP63 0.5 4.56 0.38 1.22e-5 Alcohol consumption (transferrin glycosylation); TGCT cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.87 0.47 3.72e-8 Bipolar disorder; TGCT cis rs3947 0.906 rs1692821 chr8:11699988 C/T cg02840367 chr8:11660030 FDFT1 1.0 8.13 0.59 3.82e-13 Blood protein levels; TGCT cis rs7412746 0.611 rs66847267 chr1:150875173 C/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs7192750 0.586 rs2335714 chr16:71897926 A/G cg06353428 chr16:71660113 MARVELD3 0.7 6.23 0.49 6.71e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg06640241 chr16:89574553 SPG7 0.8 9.11 0.63 1.79e-15 Multiple myeloma (IgH translocation); TGCT cis rs12142240 0.698 rs1135460 chr1:46815970 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg08645402 chr16:4508243 NA 0.21 5.31 0.43 4.99e-7 Schizophrenia; TGCT cis rs2016266 0.859 rs2886129 chr12:53731984 G/A cg16917193 chr12:54089295 NA 0.68 4.55 0.38 1.25e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs7917772 0.503 rs11191342 chr10:104344450 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 8.21 0.59 2.44e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs881375 0.900 rs1008383 chr9:123683579 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.43 0.44 2.89e-7 Rheumatoid arthritis; TGCT cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs933688 1.000 rs10041402 chr5:90738948 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.64 0.61 2.4e-14 Smoking behavior; TGCT cis rs7927592 0.546 rs683978 chr11:68192421 T/C cg16797656 chr11:68205561 LRP5 0.29 4.97 0.41 2.16e-6 Total body bone mineral density; TGCT trans rs2727020 0.554 rs7111711 chr11:49557880 G/A cg11707556 chr5:10655725 ANKRD33B -0.42 -8.63 -0.61 2.5e-14 Coronary artery disease; TGCT cis rs9788682 1.000 rs7164594 chr15:78803057 C/T cg06917634 chr15:78832804 PSMA4 -0.68 -4.98 -0.41 2.11e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs6088580 0.668 rs1205337 chr20:32926041 T/A cg08999081 chr20:33150536 PIGU -0.25 -4.85 -0.4 3.66e-6 Glomerular filtration rate (creatinine); TGCT trans rs9830388 0.625 rs4241512 chr3:23379199 T/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 RR interval (tricyclic/tetracyclic antidepressant use interaction); TGCT cis rs9611565 0.559 rs8139993 chr22:41995335 T/C cg06481639 chr22:41940642 POLR3H -0.62 -5.26 -0.43 6.21e-7 Vitiligo; TGCT cis rs2841277 0.802 rs2841269 chr14:105386149 C/G cg19901468 chr14:105411992 AHNAK2 -0.25 -5.89 -0.47 3.45e-8 Rheumatoid arthritis; TGCT cis rs4319547 0.697 rs7974262 chr12:122896385 C/T cg05707623 chr12:122985044 ZCCHC8 0.63 4.94 0.41 2.46e-6 Body mass index; TGCT cis rs854765 0.583 rs4925126 chr17:17798633 C/T cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.94e-6 Total body bone mineral density; TGCT cis rs7647973 1.000 rs13322887 chr3:49555583 G/A cg05785598 chr3:49045655 WDR6 -0.38 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT trans rs3780486 0.846 rs7849148 chr9:33138352 A/T cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT cis rs6540559 0.546 rs735693 chr1:210033988 A/C cg22029157 chr1:209979665 IRF6 0.85 6.39 0.5 3.1e-9 Cleft lip with or without cleft palate; TGCT cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg03388025 chr16:89894329 SPIRE2 0.35 5.21 0.42 7.63e-7 Vitiligo; TGCT cis rs12477438 0.520 rs6717723 chr2:99756930 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.28 0.77 1.43e-25 Chronic sinus infection; TGCT cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg08975724 chr8:8085496 FLJ10661 -0.55 -5.06 -0.41 1.47e-6 Mood instability; TGCT cis rs769267 0.930 rs4808964 chr19:19603692 A/C cg08509172 chr19:19383838 TM6SF2 0.34 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs28595532 0.920 rs55668908 chr4:119769799 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg18230493 chr5:56204884 C5orf35 -0.67 -5.88 -0.47 3.5e-8 Initial pursuit acceleration; TGCT cis rs2766692 0.956 rs35696661 chr14:100742355 G/C cg14866419 chr14:100704911 YY1 0.59 4.68 0.39 7.52e-6 Electroencephalographic traits in alcoholism; TGCT cis rs6831352 0.734 rs2851259 chr4:100033986 C/T cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs3617 0.539 rs9985365 chr3:52953844 A/G cg05573699 chr3:52720067 GNL3;PBRM1 0.47 4.63 0.38 9.24e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3793917 0.948 rs3750848 chr10:124215315 A/C cg09507567 chr10:124027408 NA 0.38 4.71 0.39 6.62e-6 Age-related macular degeneration; TGCT cis rs7659604 0.539 rs7699776 chr4:122753885 A/G cg19748678 chr4:122722346 EXOSC9 0.9 9.1 0.63 1.85e-15 Type 2 diabetes; TGCT cis rs1215050 0.782 rs6853916 chr4:98653387 C/T cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7824557 0.527 rs2736305 chr8:11237773 T/C cg21775007 chr8:11205619 TDH -0.7 -6.8 -0.52 3.92e-10 Retinal vascular caliber; TGCT cis rs6570726 0.577 rs403345 chr6:145845171 T/C cg05347473 chr6:146136440 FBXO30 0.61 5.63 0.45 1.15e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9457247 1.000 rs408040 chr6:167398903 A/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs8180040 0.966 rs11914795 chr3:47557722 G/A cg27129171 chr3:47204927 SETD2 0.62 7.36 0.55 2.26e-11 Colorectal cancer; TGCT cis rs1865760 0.964 rs6932113 chr6:25913098 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs6912958 0.558 rs9444530 chr6:88343318 C/T cg06598631 chr6:88300029 RARS2;ORC3L 0.57 5.04 0.41 1.6e-6 Monocyte percentage of white cells; TGCT cis rs2066819 1.000 rs80317430 chr12:56727705 G/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT trans rs17685 0.753 rs12531559 chr7:75631697 C/T cg19862616 chr7:65841803 NCRNA00174 -0.5 -8.43 -0.6 7.38e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6582630 0.502 rs2204008 chr12:38439203 C/T cg13010199 chr12:38710504 ALG10B 0.57 4.46 0.37 1.79e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs11190604 1.000 rs7090431 chr10:102261753 A/G cg23241863 chr10:102295624 HIF1AN 0.7 5.38 0.43 3.59e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2562456 0.876 rs2681395 chr19:21738140 T/C cg25650185 chr19:21324782 ZNF431 -0.64 -5.73 -0.46 7.12e-8 Pain; TGCT cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg03806693 chr22:41940476 POLR3H 1.15 13.16 0.76 2.69e-25 Vitiligo; TGCT cis rs344364 0.511 rs1742395 chr16:1955965 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.47 -5.43 -0.44 2.8e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9549367 0.756 rs2302756 chr13:113900197 G/A cg00898013 chr13:113819073 PROZ 0.4 4.94 0.41 2.48e-6 Platelet distribution width; TGCT cis rs17376456 0.825 rs13156202 chr5:93157721 C/T cg25358565 chr5:93447407 FAM172A -0.9 -8.07 -0.59 5.24e-13 Diabetic retinopathy; TGCT cis rs6754311 0.517 rs60453613 chr2:136527120 G/C cg07169764 chr2:136633963 MCM6 0.89 7.96 0.58 9.17e-13 Mosquito bite size; TGCT cis rs12210905 0.688 rs72845027 chr6:27528199 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs758129 0.501 rs2238297 chr15:89875066 G/A cg24365117 chr15:89879190 POLG 0.33 4.63 0.38 8.94e-6 Schizophrenia; TGCT cis rs61990749 0.597 rs2267768 chr14:78216014 A/G cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs11190604 1.000 rs11190604 chr10:102302457 A/G cg16342193 chr10:102329863 NA -0.43 -5.32 -0.43 4.69e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9291683 0.588 rs17247314 chr4:10004743 C/G cg11266682 chr4:10021025 SLC2A9 0.66 9.71 0.66 6.54e-17 Bone mineral density; TGCT cis rs2458413 0.563 rs2458422 chr8:105332817 C/T cg13045555 chr8:105342365 NA -0.39 -6.6 -0.51 1.05e-9 Paget's disease; TGCT cis rs9394841 0.667 rs10807268 chr6:41777591 A/T cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs9649213 0.614 rs59120980 chr7:98017730 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.94 -8.9 -0.62 5.66e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs17076896 0.786 rs61956073 chr13:19931292 C/T cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7647973 0.593 rs4855885 chr3:49690199 G/A cg03034192 chr3:50606346 HEMK1;C3orf18 0.37 4.81 0.4 4.32e-6 Menarche (age at onset); TGCT cis rs782590 0.643 rs13009906 chr2:55739434 A/G cg18811423 chr2:55921094 PNPT1 -0.61 -6.3 -0.49 4.71e-9 Metabolic syndrome; TGCT cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs4523957 0.651 rs4790316 chr17:2074977 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.62 -0.38 9.44e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1635 0.655 rs723476 chr6:28305104 C/T cg15743358 chr6:28303923 ZNF323 -1.29 -6.5 -0.5 1.73e-9 Schizophrenia; TGCT cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg11494091 chr17:61959527 GH2 0.44 7.34 0.55 2.52e-11 Height; TGCT cis rs1577917 0.837 rs806529 chr6:86467121 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.18 -0.42 8.84e-7 Response to antipsychotic treatment; TGCT cis rs36051895 0.589 rs17492549 chr9:5202830 A/C cg02405213 chr9:5042618 JAK2 -0.7 -8.49 -0.61 5.46e-14 Pediatric autoimmune diseases; TGCT trans rs941408 0.963 rs2537855 chr19:2806574 A/G cg22153745 chr1:153894579 GATAD2B -0.71 -6.9 -0.53 2.37e-10 Total cholesterol levels; TGCT cis rs11031096 0.683 rs10835729 chr11:4210847 T/C cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9399135 0.967 rs1854865 chr6:135360300 C/G cg24558204 chr6:135376177 HBS1L 0.46 4.56 0.38 1.23e-5 Red blood cell count; TGCT cis rs3008870 0.920 rs3008860 chr1:67391003 G/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs7044106 0.762 rs966397 chr9:123453312 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.6 6.34 0.49 3.94e-9 Hip circumference adjusted for BMI; TGCT cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg03517284 chr6:25882590 NA -0.53 -5.43 -0.44 2.88e-7 Blood metabolite levels; TGCT trans rs10504390 0.656 rs78912269 chr8:66511446 C/T cg07799219 chr22:43901523 MPPED1 -0.71 -6.88 -0.53 2.67e-10 IgG glycosylation; TGCT cis rs9393777 0.513 rs9368448 chr6:26649355 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs709400 0.663 rs72710714 chr14:103981849 T/G cg26031613 chr14:104095156 KLC1 0.87 9.32 0.64 5.5e-16 Body mass index; TGCT cis rs8070740 0.617 rs9908179 chr17:5323631 A/G cg25236894 chr17:5323110 RPAIN;NUP88 0.64 6.22 0.49 7.1e-9 Menopause (age at onset); TGCT trans rs4332037 0.851 rs10268609 chr7:1962163 A/C cg10840412 chr1:235813424 GNG4 1.07 8.91 0.62 5.31e-15 Bipolar disorder; TGCT cis rs12134245 0.776 rs61548854 chr1:92001536 C/T cg25838465 chr1:92012736 NA -0.41 -6.57 -0.51 1.23e-9 Breast cancer; TGCT cis rs3862435 0.518 rs2601170 chr15:90914209 C/T cg14166756 chr15:90894880 ZNF774 -0.32 -5.07 -0.41 1.4e-6 Response to exercise (triglyceride level interaction); TGCT cis rs4851266 1.000 rs12619178 chr2:100838157 C/T cg22139774 chr2:100720529 AFF3 -0.34 -5.09 -0.42 1.28e-6 Educational attainment; TGCT cis rs6088590 0.561 rs2295444 chr20:33173883 C/T cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs2836950 0.501 rs2836985 chr21:40701169 A/G cg11890956 chr21:40555474 PSMG1 -0.64 -5.97 -0.47 2.38e-8 Menarche (age at onset); TGCT cis rs9400467 0.537 rs73530951 chr6:111484814 G/A cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs7017914 1.000 rs13253842 chr8:71625503 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs6545883 0.929 rs1186707 chr2:61673520 C/A cg15711740 chr2:61764176 XPO1 -0.51 -4.62 -0.38 9.42e-6 Tuberculosis; TGCT cis rs3540 0.960 rs8040585 chr15:91026477 T/C cg22089800 chr15:90895588 ZNF774 0.77 7.25 0.55 4.02e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9916302 0.904 rs600010 chr17:37433517 T/C cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs35306767 0.622 rs66462130 chr10:1022108 C/T cg20503657 chr10:835505 NA 0.58 6.48 0.5 1.92e-9 Eosinophil percentage of granulocytes; TGCT cis rs10186029 0.676 rs35922168 chr2:213949018 T/C cg08319019 chr2:214017104 IKZF2 0.62 5.76 0.46 6.13e-8 Systemic sclerosis; TGCT cis rs1797081 1.000 rs2603807 chr10:16872797 A/G cg14835575 chr10:16859367 RSU1 0.4 4.61 0.38 9.76e-6 Platelet distribution width; TGCT cis rs7666738 0.830 rs11097608 chr4:99011693 T/C cg17366294 chr4:99064904 C4orf37 0.71 7.17 0.54 5.92e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs908922 0.651 rs4845442 chr1:152485545 G/A cg20991723 chr1:152506922 NA 0.48 6.68 0.51 7.04e-10 Hair morphology; TGCT cis rs7246657 0.722 rs10409605 chr19:38123137 T/G cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.7e-6 Coronary artery calcification; TGCT cis rs3771570 1.000 rs62193171 chr2:242276523 C/A cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs72781680 0.948 rs72796385 chr2:24170360 T/A cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs2180341 0.814 rs9401959 chr6:127736464 T/C cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs801193 0.548 rs2659904 chr7:66178602 C/A cg18876405 chr7:65276391 NA 0.34 4.92 0.4 2.7e-6 Aortic root size; TGCT cis rs10504229 0.906 rs113857287 chr8:58191683 T/C cg08280861 chr8:58055591 NA 0.36 4.8 0.4 4.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg01802117 chr1:53393560 SCP2 -0.42 -5.25 -0.43 6.33e-7 Monocyte count; TGCT cis rs3858526 0.959 rs1840179 chr11:5949148 A/G cg05234568 chr11:5960015 NA -0.48 -4.77 -0.39 5.08e-6 DNA methylation (variation); TGCT cis rs7209700 0.962 rs56327427 chr17:45354746 C/T cg21624342 chr17:45890973 OSBPL7 0.18 5.1 0.42 1.25e-6 IgG glycosylation; TGCT cis rs7246657 1.000 rs1529957 chr19:37739801 A/G cg18154014 chr19:37997991 ZNF793 0.68 4.69 0.39 6.97e-6 Coronary artery calcification; TGCT cis rs9447004 0.557 rs2173854 chr6:74426775 T/A cg23004174 chr6:74404879 CD109 0.21 4.53 0.38 1.37e-5 Blood protein levels;Calcium levels; TGCT cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg12756686 chr19:29218302 NA 0.69 6.7 0.52 6.51e-10 Methadone dose in opioid dependence; TGCT cis rs1008375 0.932 rs6449321 chr4:17644472 A/G cg18681998 chr4:17616180 MED28 1.05 12.0 0.73 1.69e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2268241 0.938 rs2268242 chr21:34781104 C/T cg14850771 chr21:34775459 IFNGR2 0.61 5.23 0.43 6.88e-7 Obesity-related traits; TGCT cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg02353165 chr6:42928485 GNMT 0.94 9.64 0.65 9.69e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9926296 0.715 rs2115401 chr16:89740609 A/G cg04287289 chr16:89883240 FANCA 0.51 4.96 0.41 2.29e-6 Vitiligo; TGCT cis rs902774 0.597 rs7299694 chr12:53352572 A/C cg14581129 chr12:53358946 NA -0.56 -6.14 -0.48 1.05e-8 Prostate cancer; TGCT cis rs826838 1.000 rs11514441 chr12:38775190 C/T cg26384229 chr12:38710491 ALG10B 1.08 10.86 0.7 1.01e-19 Heart rate; TGCT cis rs6121246 0.559 rs6060621 chr20:30261562 G/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs2228479 0.618 rs72477006 chr16:89950299 G/C cg19635926 chr16:89946313 TCF25 0.29 4.81 0.4 4.3e-6 Skin colour saturation; TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg07092213 chr7:1199455 ZFAND2A -0.49 -5.66 -0.45 9.81e-8 Longevity;Endometriosis; TGCT cis rs7216064 0.906 rs78452260 chr17:65848522 G/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs12701220 0.725 rs13242971 chr7:1055515 C/T cg27454412 chr7:1067447 C7orf50 -0.48 -4.45 -0.37 1.91e-5 Bronchopulmonary dysplasia; TGCT cis rs6087990 0.863 rs1569686 chr20:31367079 G/T cg13636640 chr20:31349939 DNMT3B 1.08 14.22 0.79 8.35e-28 Ulcerative colitis; TGCT cis rs1577917 0.958 rs7739241 chr6:86575796 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.71e-7 Response to antipsychotic treatment; TGCT cis rs2806561 0.514 rs7519093 chr1:23541078 A/T cg19743168 chr1:23544995 NA -0.47 -7.79 -0.57 2.32e-12 Height; TGCT cis rs2980439 0.556 rs2921059 chr8:8317887 G/T cg15556689 chr8:8085844 FLJ10661 0.7 6.45 0.5 2.3e-9 Neuroticism; TGCT cis rs9911578 1.000 rs4482353 chr17:56896834 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7752195 0.643 rs6940230 chr6:25247120 G/T cg16898833 chr6:26189333 HIST1H4D 0.97 4.58 0.38 1.1e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs12210905 1.000 rs1062834 chr6:27222539 A/G cg08851530 chr6:28072375 NA 1.06 5.05 0.41 1.55e-6 Hip circumference adjusted for BMI; TGCT cis rs3806843 1.000 rs3756339 chr5:140180537 A/G cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2404602 0.583 rs12907668 chr15:76589767 A/T cg22467129 chr15:76604101 ETFA -0.61 -7.93 -0.58 1.09e-12 Blood metabolite levels; TGCT cis rs7949030 1.000 rs7949030 chr11:62394881 A/G cg11742103 chr11:62369870 EML3;MTA2 0.51 6.88 0.53 2.64e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2120019 0.935 rs8043181 chr15:75380424 T/C cg17294928 chr15:75287854 SCAMP5 -0.87 -6.62 -0.51 9.65e-10 Blood trace element (Zn levels); TGCT cis rs4372836 0.504 rs13009357 chr2:29041877 T/C cg09522027 chr2:28974177 PPP1CB -0.56 -5.68 -0.45 9.2e-8 Body mass index; TGCT cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg03264133 chr6:25882463 NA -0.73 -7.73 -0.57 3.2e-12 Blood metabolite levels; TGCT cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs17270561 0.541 rs12192932 chr6:25911502 A/G cg17042849 chr6:26104293 HIST1H4C -0.79 -5.76 -0.46 6.33e-8 Iron status biomarkers; TGCT cis rs9633740 0.578 rs7084416 chr10:82304297 G/A cg01528321 chr10:82214614 TSPAN14 -0.85 -5.28 -0.43 5.6e-7 Post bronchodilator FEV1; TGCT cis rs265548 0.646 rs36692 chr19:17906839 C/T cg16744531 chr19:17905626 B3GNT3 0.41 5.07 0.41 1.41e-6 Tumor biomarkers; TGCT cis rs6433857 0.627 rs6741769 chr2:181500545 G/A cg23363182 chr2:181467187 NA -0.33 -5.08 -0.42 1.33e-6 Body mass index; TGCT cis rs6951245 1.000 rs6951245 chr7:1058193 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.56 -0.38 1.19e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg06640241 chr16:89574553 SPG7 0.78 9.07 0.63 2.2e-15 Multiple myeloma (IgH translocation); TGCT cis rs7617773 0.817 rs745116 chr3:48272536 T/G cg11946769 chr3:48343235 NME6 0.72 6.23 0.49 6.77e-9 Coronary artery disease; TGCT cis rs4700695 0.668 rs27961 chr5:65443352 A/C cg21114390 chr5:65439923 SFRS12 -0.76 -6.52 -0.51 1.62e-9 Facial morphology (factor 19); TGCT trans rs3780486 0.846 rs3780487 chr9:33139237 T/C cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT cis rs7267979 0.702 rs449801 chr20:25491847 C/T cg16686733 chr20:25566563 NINL 0.49 4.74 0.39 5.84e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs546131 0.928 rs552627 chr11:34826680 G/A cg06937548 chr11:34938143 PDHX;APIP 0.66 6.03 0.48 1.74e-8 Lung disease severity in cystic fibrosis; TGCT cis rs514406 0.825 rs28817407 chr1:53226116 G/A cg08859206 chr1:53392774 SCP2 0.4 5.97 0.47 2.38e-8 Monocyte count; TGCT cis rs2721195 0.816 rs4251689 chr8:145741130 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.88 9.57 0.65 1.4e-16 Age at first birth; TGCT cis rs5769765 0.862 rs56377703 chr22:50306940 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.44 6.33 0.49 4.16e-9 Schizophrenia; TGCT cis rs709400 0.628 rs2273699 chr14:103923475 A/G cg12935359 chr14:103987150 CKB -0.35 -5.38 -0.44 3.5e-7 Body mass index; TGCT cis rs7020830 0.898 rs2047010 chr9:37077947 A/G cg14294708 chr9:37120828 ZCCHC7 1.28 19.85 0.87 2.54e-40 Schizophrenia; TGCT cis rs7772486 0.875 rs2777477 chr6:146305491 A/G cg23711669 chr6:146136114 FBXO30 0.84 8.85 0.62 7.33e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 1.000 rs10484442 chr6:26555879 A/G cg15659132 chr6:26577336 NA 0.9 12.92 0.76 1.04e-24 Intelligence (multi-trait analysis); TGCT cis rs3741404 0.609 rs641430 chr11:63869531 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.72 -7.26 -0.55 3.77e-11 Platelet count; TGCT cis rs2841277 0.708 rs28600075 chr14:105408315 T/C cg21017887 chr14:105400489 NA 0.36 5.14 0.42 1.04e-6 Rheumatoid arthritis; TGCT cis rs68170813 0.559 rs77671232 chr7:106939202 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.95 -0.47 2.61e-8 Coronary artery disease; TGCT cis rs854624 0.892 rs1719194 chr17:34336054 C/G cg02022384 chr17:34097390 MMP28 -0.45 -4.47 -0.37 1.73e-5 Blood protein levels; TGCT cis rs12540874 0.698 rs13234331 chr7:50560314 G/T cg18232548 chr7:50535776 DDC -0.38 -6.53 -0.51 1.55e-9 Systemic sclerosis; TGCT cis rs7584330 0.541 rs10202181 chr2:238352099 A/G cg14458575 chr2:238380390 NA 0.51 7.51 0.56 1e-11 Prostate cancer; TGCT trans rs459571 0.635 rs379471 chr9:136890649 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.72 -7.83 -0.58 1.87e-12 Platelet distribution width; TGCT cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2692947 0.537 rs1345917 chr2:96200603 A/C cg23100626 chr2:96804247 ASTL 0.45 5.34 0.43 4.21e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg13607699 chr17:42295918 UBTF 0.59 5.4 0.44 3.23e-7 Total body bone mineral density; TGCT cis rs2718812 0.792 rs1006098 chr3:133411605 G/T cg16414030 chr3:133502952 NA 0.39 5.05 0.41 1.56e-6 Iron status biomarkers; TGCT cis rs10883723 0.737 rs7074444 chr10:104249922 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs11153730 0.503 rs369383 chr6:118618400 T/A cg21191810 chr6:118973309 C6orf204 0.27 4.55 0.38 1.27e-5 QT interval;Heart rate;QRS duration;QRS complex (Sokolow-Lyon); TGCT cis rs7523050 0.643 rs12741194 chr1:109400390 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs10174077 0.687 rs10172023 chr2:152476028 C/G cg19508488 chr2:152266495 RIF1 0.62 5.83 0.46 4.59e-8 Squamous cell lung carcinoma; TGCT cis rs614226 0.872 rs12307148 chr12:120903179 T/C cg01236616 chr12:121019343 POP5 -1.23 -12.24 -0.74 4.57e-23 Type 1 diabetes nephropathy; TGCT cis rs3026101 0.671 rs3026109 chr17:5284480 C/T cg25236894 chr17:5323110 RPAIN;NUP88 -0.48 -4.71 -0.39 6.61e-6 Body mass index; TGCT cis rs7666738 0.830 rs13108871 chr4:98803872 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.3 0.43 5e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7027203 0.828 rs3957506 chr9:96588133 C/T cg14598338 chr9:96623480 NA -0.62 -9.7 -0.66 6.89e-17 DNA methylation (variation); TGCT cis rs4455778 0.580 rs4560745 chr7:49115412 G/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7772486 0.875 rs7767660 chr6:146436550 T/C cg23711669 chr6:146136114 FBXO30 0.87 9.27 0.64 7.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs7662389 chr4:99019892 G/A cg05340658 chr4:99064831 C4orf37 0.47 5.16 0.42 9.68e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4722166 0.597 rs2069845 chr7:22770149 G/A cg05265849 chr7:22767390 IL6 0.23 4.54 0.38 1.32e-5 Lung cancer; TGCT cis rs9733 0.650 rs3738485 chr1:150552392 C/G cg13175981 chr1:150552382 MCL1 0.52 5.75 0.46 6.55e-8 Tonsillectomy; TGCT cis rs7666738 0.830 rs2865977 chr4:99017916 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.71e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs17685 0.672 rs56343450 chr7:75796235 C/T cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7714584 0.793 rs11958146 chr5:150254158 A/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs6582630 0.531 rs3850000 chr12:38483752 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT trans rs1814175 0.817 rs6486044 chr11:49982718 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs367943 1.000 rs1057827 chr5:112823768 T/C cg12552261 chr5:112820674 MCC 0.24 4.91 0.4 2.81e-6 Type 2 diabetes; TGCT cis rs4455778 0.580 rs34230450 chr7:49118157 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7975161 0.565 rs4545635 chr12:104636844 A/C cg25273343 chr12:104657179 TXNRD1 -0.35 -4.76 -0.39 5.28e-6 Toenail selenium levels; TGCT cis rs644799 0.965 rs602512 chr11:95561682 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.66 0.69 3.18e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12762955 0.561 rs1904671 chr10:1014603 G/A cg26597838 chr10:835615 NA -0.45 -6.15 -0.48 9.6e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs10992471 0.528 rs7031567 chr9:95241363 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -4.94 -0.41 2.47e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs72945132 0.882 rs58039907 chr11:70183336 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7611238 0.560 rs2275518 chr3:195102787 T/C cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.81e-6 Body mass index; TGCT cis rs6089829 0.888 rs4809465 chr20:61671156 G/C cg18188782 chr20:61659543 NA 0.44 4.88 0.4 3.17e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs910316 0.967 rs10246 chr14:75544470 T/A cg11812906 chr14:75593930 NEK9 0.74 7.18 0.54 5.58e-11 Height; TGCT cis rs36051895 0.664 rs12344629 chr9:5109208 C/T cg02405213 chr9:5042618 JAK2 -0.71 -9.43 -0.65 3.07e-16 Pediatric autoimmune diseases; TGCT cis rs1371867 0.846 rs1660330 chr8:101305015 T/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg23708337 chr7:1209742 NA 0.56 5.1 0.42 1.25e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2147959 0.824 rs12542 chr1:228682330 C/G cg22700015 chr1:228743131 NA -0.63 -4.82 -0.4 4.2e-6 Adult asthma; TGCT cis rs28386778 0.799 rs2665802 chr17:61995030 A/T cg11494091 chr17:61959527 GH2 -0.59 -16.13 -0.82 3.12e-32 Prudent dietary pattern; TGCT cis rs4665809 1.000 rs6729757 chr2:26285102 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs3540 0.618 rs11636089 chr15:91039527 C/T cg22089800 chr15:90895588 ZNF774 0.75 7.58 0.56 7.16e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2120019 0.608 rs4886414 chr15:75308650 C/T cg09165964 chr15:75287851 SCAMP5 1.13 11.71 0.72 8.48e-22 Blood trace element (Zn levels); TGCT cis rs644148 0.704 rs2686761 chr19:44989752 T/C cg15540054 chr19:45004280 ZNF180 -0.6 -4.56 -0.38 1.23e-5 Personality dimensions; TGCT cis rs60843830 0.661 rs11674325 chr2:105517 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.54 4.51 0.38 1.45e-5 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2652822 0.530 rs7165016 chr15:63439590 T/A cg12855773 chr15:63363890 TPM1 -0.19 -5.11 -0.42 1.16e-6 Metabolic traits; TGCT cis rs7659604 0.676 rs6855269 chr4:122697418 T/G cg19748678 chr4:122722346 EXOSC9 0.87 9.24 0.64 8.52e-16 Type 2 diabetes; TGCT cis rs7010267 0.596 rs4307369 chr8:120036953 A/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs3020736 0.500 rs764481 chr22:42518426 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs8017423 0.900 rs11625870 chr14:90693396 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -7.83 -0.58 1.9e-12 Mortality in heart failure; TGCT cis rs9394438 0.628 rs2153947 chr6:37544930 A/G cg00985040 chr6:37553208 NA -0.25 -4.97 -0.41 2.18e-6 IgG glycosylation; TGCT cis rs7267979 1.000 rs4815406 chr20:25341316 C/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13108904 0.517 rs13134568 chr4:1334289 G/A cg03303774 chr4:1407052 NA 0.38 6.07 0.48 1.45e-8 Obesity-related traits; TGCT cis rs1903068 0.853 rs28411232 chr4:56000009 A/T cg09978860 chr4:56023921 NA 0.57 6.47 0.5 2.1e-9 Endometriosis; TGCT cis rs1878931 0.580 rs4785932 chr16:3410456 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.93 10.42 0.68 1.18e-18 Body mass index (adult); TGCT cis rs10782582 0.609 rs2029680 chr1:76363505 A/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.48 0.37 1.66e-5 Daytime sleep phenotypes; TGCT cis rs1218582 0.710 rs4845687 chr1:154878911 A/G cg24250549 chr1:154909240 PMVK 0.65 6.49 0.5 1.84e-9 Prostate cancer; TGCT cis rs1552244 0.882 rs3755783 chr3:10029289 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.56 -0.51 1.31e-9 Alzheimer's disease; TGCT cis rs7523273 0.565 rs11118453 chr1:207887996 A/C cg22525895 chr1:207977042 MIR29B2 0.35 5.75 0.46 6.66e-8 Schizophrenia; TGCT cis rs9807989 0.507 rs10208196 chr2:102996345 G/A cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs4595586 0.505 rs12827467 chr12:39374014 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg16423285 chr20:60520624 NA 0.68 7.07 0.54 1.02e-10 Body mass index; TGCT trans rs629535 0.773 rs569064 chr8:70065967 A/G cg21567404 chr3:27674614 NA 0.57 9.11 0.63 1.82e-15 Dupuytren's disease; TGCT cis rs7586879 0.681 rs6723803 chr2:25120713 G/C cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs7959452 0.557 rs899224 chr12:69784774 A/G cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs8177253 0.930 rs12595 chr3:133496553 T/C cg11941060 chr3:133502564 NA -0.29 -6.21 -0.49 7.41e-9 Iron status biomarkers; TGCT cis rs10791323 0.604 rs2853115 chr11:133707908 C/T cg15485101 chr11:133734466 NA -0.4 -5.2 -0.42 7.81e-7 Childhood ear infection; TGCT cis rs854765 0.624 rs4925116 chr17:17731200 A/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.52 -0.38 1.42e-5 Total body bone mineral density; TGCT cis rs6988636 1.000 rs57165742 chr8:124184559 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs6582630 0.519 rs2387812 chr12:38381480 A/G cg26384229 chr12:38710491 ALG10B 0.81 7.13 0.54 7.23e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg13607699 chr17:42295918 UBTF 0.6 5.46 0.44 2.47e-7 Total body bone mineral density; TGCT cis rs7829975 0.509 rs2945269 chr8:8115578 G/C cg15556689 chr8:8085844 FLJ10661 0.68 6.42 0.5 2.65e-9 Mood instability; TGCT cis rs1568889 0.838 rs1483858 chr11:28189639 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 10.94 0.7 6.46e-20 Bipolar disorder; TGCT cis rs724767 1.000 rs724767 chr3:193722330 C/T cg19410732 chr3:194305082 NA -0.59 -4.58 -0.38 1.13e-5 Estradiol plasma levels (breast cancer); TGCT cis rs9534288 0.699 rs9534320 chr13:46665572 A/G cg15192986 chr13:46630673 CPB2 -0.51 -6.11 -0.48 1.19e-8 Blood protein levels; TGCT cis rs9807989 0.507 rs3732124 chr2:103018052 A/G cg03938978 chr2:103052716 IL18RAP -0.26 -5.23 -0.42 7.11e-7 Asthma; TGCT cis rs9914544 0.545 rs34417974 chr17:18773636 T/C cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.02e-6 Educational attainment (years of education); TGCT cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg23172400 chr8:95962367 TP53INP1 0.36 5.6 0.45 1.33e-7 Type 2 diabetes; TGCT cis rs7119 0.651 rs12909292 chr15:77837982 G/T cg27398640 chr15:77910606 LINGO1 -0.28 -5.12 -0.42 1.12e-6 Type 2 diabetes; TGCT cis rs7824557 0.564 rs7821459 chr8:11236681 T/G cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs11098499 0.954 rs6838814 chr4:120392443 G/A cg09307838 chr4:120376055 NA 0.69 6.56 0.51 1.31e-9 Corneal astigmatism; TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg17775962 chr7:1200435 ZFAND2A 0.31 5.2 0.42 8.11e-7 Longevity;Endometriosis; TGCT cis rs589249 1.000 rs218989 chr1:37166715 G/T cg04012535 chr1:37176647 NA -0.31 -4.96 -0.41 2.28e-6 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs9910055 0.659 rs7207464 chr17:42245033 C/T cg19774624 chr17:42201019 HDAC5 -0.89 -11.07 -0.7 3.17e-20 Total body bone mineral density; TGCT cis rs10791323 0.660 rs10791330 chr11:133727535 C/T cg15485101 chr11:133734466 NA 0.35 4.59 0.38 1.09e-5 Childhood ear infection; TGCT cis rs2075371 1.000 rs2504 chr7:133979545 A/T cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs422249 0.547 rs174535 chr11:61551356 T/C cg01500311 chr11:61656094 FADS3 -0.34 -5.66 -0.45 9.97e-8 Trans fatty acid levels; TGCT cis rs9914988 0.887 rs11656272 chr17:27091153 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs12971120 0.891 rs3794953 chr18:72180519 C/T cg25817165 chr18:72167213 CNDP2 -0.27 -4.66 -0.39 7.94e-6 Refractive error; TGCT cis rs849210 0.517 rs12468794 chr2:206190721 A/G cg11793701 chr2:206547163 NRP2 -0.56 -4.5 -0.37 1.54e-5 Tonsillectomy; TGCT cis rs6489785 0.509 rs4767937 chr12:121223244 G/C cg02419362 chr12:121203948 SPPL3 0.19 4.47 0.37 1.74e-5 Longevity;Allergic disease (asthma, hay fever or eczema); TGCT cis rs929596 0.614 rs10929302 chr2:234665782 G/A cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.34 -5.49 -0.44 2.13e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs4242434 0.672 rs7830206 chr8:22485375 C/T cg03733263 chr8:22462867 KIAA1967 0.98 12.7 0.75 3.48e-24 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs3812831 0.695 rs7995986 chr13:114938802 A/G cg15513719 chr13:114904418 NA 0.36 4.51 0.38 1.46e-5 Schizophrenia; TGCT cis rs12950390 0.853 rs11655336 chr17:45858836 A/G cg06532163 chr17:45867833 NA -0.36 -5.76 -0.46 6.14e-8 IgG glycosylation; TGCT cis rs2562456 0.833 rs2968078 chr19:21641744 A/G cg01304269 chr19:21688519 ZNF429 -0.6 -4.89 -0.4 3.07e-6 Pain; TGCT cis rs7246657 0.722 rs2927746 chr19:38156570 G/A cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs3125734 0.608 rs7094950 chr10:64019744 T/C cg19640130 chr10:64028056 RTKN2 -0.4 -5.11 -0.42 1.17e-6 Rheumatoid arthritis; TGCT cis rs10832169 0.967 rs4534565 chr11:14065598 C/T cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT trans rs2243480 1.000 rs1618893 chr7:66096119 C/T cg07424592 chr7:64974309 NA 1.37 7.99 0.58 7.88e-13 Diabetic kidney disease; TGCT cis rs7216064 0.954 rs4790973 chr17:65951133 C/T cg12091567 chr17:66097778 LOC651250 -0.82 -6.2 -0.49 7.54e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs739401 0.572 rs389285 chr11:3062673 G/A cg25174290 chr11:3078921 CARS 0.47 4.51 0.38 1.49e-5 Longevity; TGCT cis rs2645424 0.671 rs2294138 chr8:11705139 C/T cg12568669 chr8:11666485 FDFT1 -0.35 -4.5 -0.37 1.52e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs896854 0.902 rs896852 chr8:95960886 G/T cg23172400 chr8:95962367 TP53INP1 -0.38 -6.49 -0.5 1.84e-9 Type 2 diabetes; TGCT cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.55 5.39 0.44 3.47e-7 Menarche (age at onset); TGCT cis rs1059312 0.808 rs4760537 chr12:129301299 C/A cg09035930 chr12:129282057 SLC15A4 0.56 10.49 0.69 8.05e-19 Systemic lupus erythematosus; TGCT cis rs7833790 0.927 rs61020899 chr8:82757090 C/T cg27398817 chr8:82754497 SNX16 0.84 6.06 0.48 1.52e-8 Diastolic blood pressure; TGCT cis rs6429082 0.783 rs291365 chr1:235688043 A/G cg26050004 chr1:235667680 B3GALNT2 0.64 5.99 0.47 2.13e-8 Adiposity; TGCT cis rs832540 0.898 rs252890 chr5:56226410 T/C cg12311346 chr5:56204834 C5orf35 -0.43 -4.58 -0.38 1.11e-5 Coronary artery disease; TGCT cis rs4478037 0.822 rs9826234 chr3:33123832 A/C cg19404215 chr3:33155277 CRTAP 0.98 5.13 0.42 1.1e-6 Major depressive disorder; TGCT cis rs9910055 1.000 rs9910055 chr17:42283037 C/T cg13607699 chr17:42295918 UBTF 0.82 7.0 0.53 1.41e-10 Total body bone mineral density; TGCT cis rs9659323 1.000 rs10923715 chr1:119535334 A/T cg07961512 chr1:119535619 NA -0.44 -4.93 -0.4 2.57e-6 Body mass index; TGCT cis rs11696501 0.688 rs6065866 chr20:44323440 G/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs10782582 0.593 rs11163967 chr1:76154185 T/C cg10523679 chr1:76189770 ACADM -0.69 -7.19 -0.54 5.26e-11 Daytime sleep phenotypes; TGCT cis rs7659604 0.521 rs4833773 chr4:122689245 C/T cg19748678 chr4:122722346 EXOSC9 -0.56 -5.53 -0.44 1.79e-7 Type 2 diabetes; TGCT cis rs10751667 0.643 rs10902234 chr11:935578 A/G cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs3733585 0.673 rs4467564 chr4:9953472 G/T cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg24250549 chr1:154909240 PMVK 0.64 6.48 0.5 1.95e-9 Prostate cancer; TGCT trans rs57221529 0.766 rs56278696 chr5:582669 A/G cg25482853 chr8:67687455 SGK3 1.2 10.12 0.67 6.42e-18 Lung disease severity in cystic fibrosis; TGCT cis rs12497850 0.931 rs6446253 chr3:48911443 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs751728 0.664 rs943474 chr6:33749834 G/C cg13859433 chr6:33739653 LEMD2 -0.32 -5.67 -0.45 9.47e-8 Crohn's disease; TGCT cis rs9787249 0.957 rs7548120 chr1:40204424 A/T cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs12477438 0.765 rs12470471 chr2:99689141 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.74 7.5 0.56 1.04e-11 Chronic sinus infection; TGCT cis rs4819052 0.959 rs8130866 chr21:46672112 G/A cg06618935 chr21:46677482 NA -0.38 -4.86 -0.4 3.44e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs860295 0.529 rs1475766 chr1:155981489 C/G cg05700447 chr1:155978627 NA -0.19 -4.75 -0.39 5.44e-6 Body mass index; TGCT cis rs9611565 0.546 rs2092274 chr22:42123737 A/G cg06481639 chr22:41940642 POLR3H 0.71 6.48 0.5 1.95e-9 Vitiligo; TGCT cis rs11718455 0.618 rs35351588 chr3:43926386 C/G cg08738300 chr3:44038990 NA 0.8 5.29 0.43 5.45e-7 Coronary artery disease; TGCT cis rs2204008 0.837 rs7301679 chr12:37989629 T/C cg26384229 chr12:38710491 ALG10B -0.7 -6.12 -0.48 1.11e-8 Bladder cancer; TGCT cis rs593531 0.571 rs11236088 chr11:74094343 A/G cg25592907 chr11:73676012 DNAJB13 0.35 4.94 0.41 2.48e-6 Neuroticism; TGCT cis rs11586313 0.649 rs61815701 chr1:152887412 G/A cg07796016 chr1:152779584 LCE1C -0.46 -5.14 -0.42 1.06e-6 Vitamin D levels; TGCT cis rs7666738 0.791 rs13120773 chr4:98972589 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6089829 0.962 rs2872543 chr20:61665017 G/A cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg11494091 chr17:61959527 GH2 0.43 7.37 0.55 2.07e-11 Height; TGCT cis rs739496 0.579 rs10774640 chr12:112295190 T/C cg10833066 chr12:111807467 FAM109A 0.41 6.14 0.48 1.02e-8 Platelet count; TGCT cis rs5769765 1.000 rs5770755 chr22:50280136 T/C cg15316289 chr22:50310904 ALG12;CRELD2 -0.39 -5.79 -0.46 5.34e-8 Schizophrenia; TGCT cis rs6484504 0.532 rs10835757 chr11:31281902 C/T cg14844989 chr11:31128820 NA -0.26 -5.0 -0.41 1.9e-6 Red blood cell count; TGCT cis rs1406084 0.636 rs12476730 chr2:154719309 C/T cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs4664293 0.836 rs13421392 chr2:160658296 G/A cg00829656 chr2:159791884 NA 0.24 4.53 0.38 1.37e-5 Monocyte percentage of white cells; TGCT trans rs3848445 1.000 rs7214411 chr17:14288990 C/T cg07670188 chr12:124066860 NA 0.98 7.16 0.54 6.35e-11 Protein quantitative trait loci; TGCT cis rs6752107 0.901 rs11687982 chr2:234149039 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.79 0.4 4.61e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs55692411 0.537 rs71326904 chr3:49991060 C/T cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs7659724 chr4:98944063 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6964587 0.967 rs28399886 chr7:91638451 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs9467773 1.000 rs4713008 chr6:26538268 T/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT trans rs1499614 1.000 rs2141924 chr7:66186246 C/T cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg03517284 chr6:25882590 NA -0.62 -5.65 -0.45 1.03e-7 Intelligence (multi-trait analysis); TGCT cis rs13064411 0.696 rs7613546 chr3:113228019 G/A cg10517650 chr3:113235015 CCDC52 -0.32 -4.45 -0.37 1.85e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg12310025 chr6:25882481 NA -0.61 -5.39 -0.44 3.38e-7 Intelligence (multi-trait analysis); TGCT cis rs17473412 0.864 rs1864046 chr5:122740921 G/T cg15125798 chr5:122621645 NA -0.55 -4.9 -0.4 2.9e-6 Total body bone mineral density; TGCT cis rs2204008 0.744 rs11168870 chr12:37973333 A/G cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs7552404 0.889 rs1250874 chr1:76190978 A/G cg10523679 chr1:76189770 ACADM 0.85 9.49 0.65 2.17e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12643440 0.538 rs2041444 chr4:17138005 A/C cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs6964587 1.000 rs9691325 chr7:91731047 G/A cg22709100 chr7:91322751 NA 0.29 4.81 0.4 4.28e-6 Breast cancer; TGCT cis rs881375 1.000 rs10760118 chr9:123641616 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.52 0.44 1.92e-7 Rheumatoid arthritis; TGCT cis rs2948294 0.588 rs12544596 chr8:8116346 A/T cg15556689 chr8:8085844 FLJ10661 0.75 6.41 0.5 2.81e-9 Red cell distribution width; TGCT cis rs2404602 0.583 rs2456076 chr15:76557553 T/G cg22467129 chr15:76604101 ETFA 0.64 8.34 0.6 1.2e-13 Blood metabolite levels; TGCT cis rs739496 0.579 rs7296199 chr12:112291844 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9443645 0.869 rs11754419 chr6:79729648 A/G cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs28785552 0.897 rs10424736 chr19:53239176 G/A cg04754360 chr19:53238445 ZNF611 -0.71 -5.64 -0.45 1.11e-7 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs6952808 0.743 rs4721097 chr7:1877503 G/T cg22963979 chr7:1858916 MAD1L1 -0.31 -4.78 -0.39 4.9e-6 Bipolar disorder and schizophrenia; TGCT cis rs2836950 0.527 rs2836948 chr21:40599677 T/C cg06238570 chr21:40685208 BRWD1 -0.6 -6.21 -0.49 7.27e-9 Menarche (age at onset); TGCT cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg00149659 chr3:10157352 C3orf10 0.92 5.88 0.47 3.58e-8 Alzheimer's disease; TGCT cis rs2404602 0.692 rs58361452 chr15:76973372 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs13191362 1.000 rs36042757 chr6:163004744 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1670533 1.000 rs12645644 chr4:1054159 C/T cg27284194 chr4:1044797 NA 0.65 5.96 0.47 2.41e-8 Recombination rate (females); TGCT cis rs1577917 0.771 rs2842609 chr6:86296788 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs4930561 0.714 rs11228151 chr11:67949371 C/G cg04465784 chr11:67976953 SUV420H1 -0.38 -5.47 -0.44 2.37e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs231513 0.813 rs231495 chr17:41976748 G/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs2361710 0.668 rs4889830 chr17:78114528 G/A cg09238746 chr17:78121135 EIF4A3 -0.76 -7.24 -0.55 4.14e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs713587 0.525 rs11675457 chr2:25079770 C/T cg01884057 chr2:25150051 NA 0.3 5.78 0.46 5.69e-8 Body mass index in non-asthmatics; TGCT trans rs2688608 0.530 rs71507081 chr10:75493136 G/A cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs78487399 0.764 rs12473987 chr2:43812180 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4819852 0.958 rs758374 chr22:19971552 T/C cg07821417 chr22:19972146 ARVCF 0.21 5.37 0.43 3.81e-7 Pulse pressure; TGCT cis rs11718455 0.920 rs4682927 chr3:44033299 C/A cg08738300 chr3:44038990 NA 0.86 6.57 0.51 1.23e-9 Coronary artery disease; TGCT cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.56 4.81 0.4 4.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9325144 0.647 rs1875609 chr12:39018259 C/T cg10518543 chr12:38710700 ALG10B -0.5 -4.8 -0.4 4.45e-6 Morning vs. evening chronotype; TGCT cis rs9926296 0.548 rs12447465 chr16:89829895 C/T cg27121462 chr16:89883253 FANCA 0.78 8.52 0.61 4.57e-14 Vitiligo; TGCT cis rs4824093 0.610 rs73443906 chr22:50274293 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.48 4.97 0.41 2.17e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7980687 0.506 rs1611973 chr12:123622731 C/G cg00376283 chr12:123451042 ABCB9 0.84 7.66 0.57 4.68e-12 Height;Educational attainment;Head circumference (infant); TGCT cis rs7945705 0.714 rs2653570 chr11:8987823 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.43 -4.79 -0.4 4.65e-6 Hemoglobin concentration; TGCT cis rs1401999 0.966 rs2292998 chr3:183663833 T/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.56e-20 Anterior chamber depth; TGCT cis rs7843479 0.582 rs11135743 chr8:21803008 A/G cg17168535 chr8:21777572 XPO7 0.8 7.91 0.58 1.23e-12 Mean corpuscular volume; TGCT cis rs7513165 0.935 rs2510 chr1:204161591 T/C cg04791601 chr1:204159016 NA 0.26 5.21 0.42 7.78e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs2120019 0.938 rs2304903 chr15:75315778 A/G cg09165964 chr15:75287851 SCAMP5 -1.14 -10.33 -0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs35883536 0.647 rs1995142 chr1:101041174 G/A cg10298815 chr1:101004474 GPR88 0.25 4.66 0.39 8.05e-6 Monocyte count; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg18538332 chr22:24372958 LOC391322 -1.02 -13.27 -0.77 1.51e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10782582 0.609 rs5745331 chr1:76273313 A/G cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs2996428 0.667 rs16824230 chr1:3766240 A/G cg13057898 chr1:3703894 LRRC47 0.21 4.61 0.38 9.9e-6 Red cell distribution width; TGCT cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9807989 0.839 rs13392100 chr2:102982094 C/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs1691799 0.867 rs1168343 chr12:66758581 C/T cg16791601 chr12:66731901 HELB -0.29 -6.18 -0.49 8.39e-9 White blood cell count (basophil); TGCT cis rs10883723 0.669 rs2001595 chr10:104395085 C/T cg05855489 chr10:104503620 C10orf26 -0.57 -4.69 -0.39 7.15e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs75686122 0.772 rs78303485 chr8:104552916 G/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs4478037 1.000 rs59622575 chr3:33162249 A/C cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs2228479 0.867 rs62056110 chr16:89946388 A/C cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs7647973 0.626 rs9829155 chr3:49817450 T/C cg03060546 chr3:49711283 APEH -0.63 -5.63 -0.45 1.12e-7 Menarche (age at onset); TGCT trans rs7615952 0.736 rs13063122 chr3:125643860 G/A cg07211511 chr3:129823064 LOC729375 -0.48 -8.0 -0.58 7.7e-13 Blood pressure (smoking interaction); TGCT cis rs6754311 0.731 rs2236783 chr2:136594158 G/A cg07169764 chr2:136633963 MCM6 -0.61 -5.57 -0.45 1.53e-7 Mosquito bite size; TGCT cis rs7666738 0.861 rs28829607 chr4:98964325 G/C cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3733585 0.673 rs4467563 chr4:9953460 A/T cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -1.06 -14.78 -0.8 3.86e-29 Menarche (age at onset); TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg19626725 chr5:178986131 RUFY1 0.55 7.64 0.57 5.16e-12 Lung cancer; TGCT cis rs56104184 0.775 rs17272707 chr19:49404535 T/G cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs854572 0.600 rs705382 chr7:94955221 C/G cg01874867 chr7:94954059 PON1 -0.34 -4.98 -0.41 2.05e-6 Paraoxonase activity; TGCT cis rs7666738 0.830 rs34916200 chr4:98851593 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9302065 0.681 rs9524903 chr13:95963565 A/G cg26751094 chr13:95954534 ABCC4 -0.34 -5.38 -0.44 3.57e-7 Blood metabolite levels; TGCT cis rs80282103 0.867 rs11819178 chr10:1098417 A/G cg08668510 chr10:1095578 IDI1 1.12 4.65 0.39 8.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs3617 0.652 rs7630552 chr3:52891570 G/C cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6.08e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4746818 1.000 rs6480383 chr10:70890482 C/T cg04149295 chr10:70884716 VPS26A 0.79 5.4 0.44 3.22e-7 Left atrial antero-posterior diameter; TGCT cis rs6089829 0.962 rs1060490 chr20:61665871 A/G cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs78487399 0.908 rs17031116 chr2:43833013 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.69 0.39 7.06e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7943191 0.768 rs34065644 chr11:62371938 C/T cg11742103 chr11:62369870 EML3;MTA2 0.55 6.35 0.5 3.71e-9 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9818758 0.607 rs67060340 chr3:48915321 C/T cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1215050 0.791 rs783969 chr4:98906504 C/T cg17366294 chr4:99064904 C4orf37 0.53 5.65 0.45 1.03e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg26668828 chr6:292823 DUSP22 -0.83 -8.57 -0.61 3.38e-14 Menopause (age at onset); TGCT cis rs7772486 0.875 rs6909827 chr6:146365738 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1460583 1.000 rs34311536 chr8:106105905 A/G cg13963735 chr8:106810858 ZFPM2 0.27 4.5 0.37 1.53e-5 Schizophrenia; TGCT cis rs7909074 0.831 rs7903412 chr10:45382361 C/T cg04218760 chr10:45406644 TMEM72 -0.29 -5.63 -0.45 1.15e-7 Mean corpuscular volume; TGCT cis rs11031096 0.655 rs12293706 chr11:4211581 C/G cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2857078 0.720 rs9901595 chr17:42305699 G/A cg13607699 chr17:42295918 UBTF 0.96 10.81 0.7 1.38e-19 Red cell distribution width;Reticulocyte count; TGCT cis rs2456568 0.802 rs10831139 chr11:93640537 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.35 -0.5 3.73e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs916888 0.610 rs199444 chr17:44818276 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.64 4.91 0.4 2.82e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg13342137 chr4:2252803 MXD4 0.17 4.47 0.37 1.71e-5 Obesity-related traits; TGCT cis rs911186 0.679 rs67330695 chr6:27103654 G/A cg16898833 chr6:26189333 HIST1H4D 0.79 4.76 0.39 5.31e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs1005277 0.579 rs1780121 chr10:38529437 C/A cg17830980 chr10:43048298 ZNF37B -0.83 -10.39 -0.68 1.4e-18 Extrinsic epigenetic age acceleration; TGCT cis rs6586163 0.872 rs7914490 chr10:90747447 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.38 -4.78 -0.39 4.79e-6 Chronic lymphocytic leukemia; TGCT cis rs9355610 0.727 rs2247315 chr6:167370211 A/C cg23791538 chr6:167370224 RNASET2 0.63 6.04 0.48 1.64e-8 Graves' disease; TGCT cis rs950027 0.620 rs1145076 chr15:45684508 G/T cg14582100 chr15:45693742 SPATA5L1 0.46 5.9 0.47 3.31e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs6988636 1.000 rs16898084 chr8:124190377 A/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT trans rs1864729 1.000 rs2567769 chr8:98297848 G/A cg08679828 chr8:102218111 ZNF706 -1.05 -7.0 -0.53 1.44e-10 Estradiol plasma levels (breast cancer); TGCT cis rs7027203 0.521 rs9299412 chr9:96523268 G/T cg14598338 chr9:96623480 NA -0.49 -7.04 -0.53 1.18e-10 DNA methylation (variation); TGCT cis rs988712 0.705 rs879048 chr11:27638934 A/C cg10635145 chr11:27742435 BDNF -0.35 -4.81 -0.4 4.34e-6 Obesity; TGCT cis rs79349575 0.783 rs318090 chr17:46991752 G/A cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs4906332 0.966 rs59858038 chr14:103867102 C/T cg26031613 chr14:104095156 KLC1 -0.51 -4.65 -0.39 8.49e-6 Coronary artery disease; TGCT cis rs7572733 0.576 rs4850441 chr2:198913413 A/G cg00792783 chr2:198669748 PLCL1 -0.59 -5.15 -0.42 1.01e-6 Dermatomyositis; TGCT cis rs28830936 0.510 rs12440605 chr15:42102285 A/G cg17847044 chr15:42102381 MAPKBP1 0.18 5.12 0.42 1.13e-6 Diastolic blood pressure; TGCT cis rs3796352 1.000 rs13072395 chr3:52980573 T/C cg15956490 chr3:53032818 SFMBT1 0.61 6.11 0.48 1.17e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6088590 0.930 rs6087618 chr20:33288407 C/T cg24642439 chr20:33292090 TP53INP2 0.68 6.23 0.49 6.81e-9 Coronary artery disease; TGCT cis rs74233809 1.000 rs17115213 chr10:104681143 A/G cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs72634258 0.945 rs12740409 chr1:8027830 A/C cg23986158 chr1:8847014 RERE 0.29 4.63 0.38 9.17e-6 Inflammatory bowel disease; TGCT cis rs1205863 1.000 rs1205864 chr6:11943595 A/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs933688 0.938 rs10063683 chr5:90714595 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.35 0.6 1.17e-13 Smoking behavior; TGCT cis rs2404602 0.716 rs17363713 chr15:76746128 G/C cg22467129 chr15:76604101 ETFA -0.57 -6.83 -0.52 3.31e-10 Blood metabolite levels; TGCT cis rs6570726 0.967 rs7772286 chr6:145930423 A/T cg05347473 chr6:146136440 FBXO30 -0.53 -4.86 -0.4 3.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7917772 0.582 rs10883738 chr10:104321721 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg02953382 chr22:24373134 LOC391322 -0.79 -8.29 -0.6 1.55e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7662987 0.517 rs2851256 chr4:100039549 G/A cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs112591243 0.685 rs74671132 chr21:47963485 T/C cg10657630 chr21:48055338 PRMT2 1.03 4.64 0.38 8.57e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9381040 0.610 rs6940356 chr6:41020360 C/T cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT cis rs1552244 0.572 rs6797536 chr3:10168802 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 0.45 5.49 0.44 2.22e-7 Alzheimer's disease; TGCT cis rs7772486 0.720 rs9403757 chr6:146261271 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13190036 1.000 rs13167431 chr5:176621075 G/C cg18465082 chr5:176734745 MXD3 0.32 4.44 0.37 1.95e-5 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs17122693 0.818 rs72681645 chr14:51155209 G/A cg04730355 chr14:51134070 SAV1 1.18 8.37 0.6 1.02e-13 Cognitive performance; TGCT cis rs765787 0.505 rs4439707 chr15:45524216 G/A cg24006582 chr15:45444508 DUOX1 0.24 5.29 0.43 5.3e-7 Uric acid levels; TGCT cis rs2242116 0.796 rs7623898 chr3:46974172 C/T cg27129171 chr3:47204927 SETD2 -0.65 -6.37 -0.5 3.28e-9 Birth weight; TGCT trans rs2688608 0.672 rs2633321 chr10:75693695 C/T cg13918328 chr10:52500089 ASAH2B 0.7 7.15 0.54 6.73e-11 Inflammatory bowel disease; TGCT cis rs6809651 0.524 rs79262908 chr3:185803594 C/T cg00760338 chr3:185826511 ETV5 -0.79 -6.45 -0.5 2.23e-9 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs11711311 0.955 rs78029398 chr3:113421321 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.68 -6.01 -0.48 1.89e-8 IgG glycosylation; TGCT cis rs1372520 0.684 rs1811442 chr4:90747751 C/T cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs10540 1.000 rs12421457 chr11:505780 T/C cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs10493773 0.630 rs3753790 chr1:86174772 T/C cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs67340775 0.541 rs200966 chr6:27862152 T/C cg26587870 chr6:27730563 NA -0.31 -4.48 -0.37 1.67e-5 Lung cancer in ever smokers; TGCT cis rs9859260 0.744 rs539816 chr3:195784076 T/A cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs2204008 0.630 rs1283300 chr12:38150227 C/T cg26384229 chr12:38710491 ALG10B -0.58 -5.08 -0.42 1.33e-6 Bladder cancer; TGCT cis rs10875595 0.836 rs7703869 chr5:140666494 C/T cg24830062 chr5:140700576 TAF7 -0.6 -5.08 -0.42 1.34e-6 Pulmonary function decline; TGCT cis rs11690462 0.963 rs6748996 chr2:26590084 T/G cg04726446 chr2:26624865 C2orf39 0.44 4.73 0.39 5.97e-6 Coronary artery disease; TGCT cis rs2718812 0.766 rs10935071 chr3:133394159 T/C cg08048268 chr3:133502702 NA -0.38 -4.7 -0.39 6.68e-6 Iron status biomarkers; TGCT cis rs4372836 0.729 rs6547873 chr2:28981983 G/A cg09522027 chr2:28974177 PPP1CB -0.68 -6.93 -0.53 2e-10 Body mass index; TGCT cis rs7267979 0.966 rs2227892 chr20:25264814 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7674212 0.556 rs6533039 chr4:103859538 A/G cg16532752 chr4:104119610 CENPE -0.6 -5.31 -0.43 4.86e-7 Type 2 diabetes; TGCT cis rs8179 0.593 rs7804722 chr7:92288106 C/T cg15732164 chr7:92237376 CDK6 0.27 4.77 0.39 5e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs9911578 0.813 rs12452313 chr17:57129882 C/A cg12560992 chr17:57184187 TRIM37 -0.79 -8.78 -0.62 1.1e-14 Intelligence (multi-trait analysis); TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg15383120 chr6:291909 DUSP22 -0.67 -6.91 -0.53 2.3e-10 Menopause (age at onset); TGCT cis rs4808199 1.000 rs12977524 chr19:19568244 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.15 0.42 9.94e-7 Nonalcoholic fatty liver disease; TGCT cis rs611744 0.967 rs641820 chr8:109190717 T/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs308447 0.516 rs732676 chr4:123717476 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.63 5.93 0.47 2.78e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs9549367 0.789 rs2302757 chr13:113909339 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs9436747 0.641 rs3790424 chr1:66044013 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.65 0.39 8.37e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs3020736 0.500 rs2413669 chr22:42507748 A/C cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9916302 0.808 rs6503515 chr17:37606433 G/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs367943 1.000 rs348944 chr5:112822925 C/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs9303542 0.559 rs12602539 chr17:46617459 T/A cg25032089 chr17:46643351 HOXB3 0.56 5.34 0.43 4.22e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6500602 0.826 rs9932461 chr16:4454170 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.47 0.5 2.03e-9 Schizophrenia; TGCT cis rs6121246 0.609 rs2376998 chr20:30340663 T/C cg13852791 chr20:30311386 BCL2L1 0.84 8.15 0.59 3.38e-13 Mean corpuscular hemoglobin; TGCT cis rs62064224 0.702 rs2302277 chr17:30791509 C/G cg25809561 chr17:30822961 MYO1D 0.3 5.2 0.42 7.96e-7 Schizophrenia; TGCT cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg26818010 chr10:134567672 INPP5A -0.35 -4.94 -0.41 2.48e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2579519 0.547 rs11683523 chr2:96544855 T/C cg13655245 chr2:97463316 CNNM4 0.15 4.51 0.38 1.51e-5 Diastolic blood pressure; TGCT cis rs3026101 0.671 rs8081480 chr17:5282761 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.52 0.38 1.41e-5 Body mass index; TGCT cis rs2033711 0.840 rs3764533 chr19:58929194 A/G cg04608855 chr19:58913158 NA 0.58 5.69 0.46 8.64e-8 Uric acid clearance; TGCT cis rs1371867 0.817 rs1660315 chr8:101332956 G/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs4665809 1.000 rs4665816 chr2:26305094 G/C cg25036284 chr2:26402008 FAM59B -0.56 -4.88 -0.4 3.2e-6 Gut microbiome composition (summer); TGCT cis rs9443189 0.570 rs504446 chr6:76326939 T/C cg01950844 chr6:76311363 SENP6 0.99 6.27 0.49 5.49e-9 Prostate cancer; TGCT cis rs367615 0.704 rs72802966 chr5:108846754 T/G cg17395555 chr5:108820864 NA 0.31 5.72 0.46 7.47e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs12291225 0.679 rs7934671 chr11:14305101 C/T cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs7819412 0.564 rs10503415 chr8:10983921 C/G cg21775007 chr8:11205619 TDH -0.59 -5.58 -0.45 1.45e-7 Triglycerides; TGCT cis rs651907 0.513 rs34963630 chr3:101504817 C/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs6540559 1.000 rs1044516 chr1:209959614 G/T cg22029157 chr1:209979665 IRF6 0.77 6.34 0.5 3.81e-9 Cleft lip with or without cleft palate; TGCT cis rs3845702 0.736 rs3845701 chr2:180826781 A/G cg01881094 chr2:180872142 CWC22 -1.05 -6.78 -0.52 4.27e-10 Schizophrenia; TGCT cis rs10504229 0.683 rs11786845 chr8:58133642 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9682041 0.800 rs7643085 chr3:170070371 A/G cg11886554 chr3:170076028 SKIL 0.71 5.62 0.45 1.2e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7100689 0.598 rs2342815 chr10:82086532 T/C cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.36 -5.46 -0.44 2.54e-7 Alzheimer's disease; TGCT cis rs769267 0.930 rs6511038 chr19:19607564 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs9915657 0.660 rs2241170 chr17:70070989 G/C cg06234051 chr17:70120541 SOX9 -0.25 -5.3 -0.43 5.03e-7 Thyroid hormone levels; TGCT cis rs56104184 0.779 rs73061627 chr19:49360418 C/T cg21252483 chr19:49399788 TULP2 -0.39 -4.94 -0.41 2.43e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs12142240 0.698 rs17361950 chr1:46864150 C/T cg14993813 chr1:46806288 NSUN4 -0.61 -4.99 -0.41 1.97e-6 Menopause (age at onset); TGCT cis rs933688 1.000 rs11948075 chr5:90680579 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.91e-14 Smoking behavior; TGCT cis rs6688613 0.840 rs6695609 chr1:166953866 A/C cg07049167 chr1:166818506 POGK -0.26 -5.18 -0.42 8.56e-7 Refractive astigmatism; TGCT cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.1 0.42 1.24e-6 Menopause (age at onset); TGCT cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.2 -0.42 7.9e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4953076 0.573 rs2054005 chr2:44401843 C/T cg00619915 chr2:44497795 NA -0.22 -4.97 -0.41 2.16e-6 Height; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg20007245 chr22:24372913 LOC391322 0.76 6.29 0.49 4.92e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs17221829 0.899 rs10160328 chr11:89462164 A/G cg02982614 chr11:89391479 FOLH1B -0.3 -5.29 -0.43 5.47e-7 Anxiety in major depressive disorder; TGCT cis rs11648796 0.757 rs763206 chr16:770103 C/G cg27144592 chr16:783916 NARFL 0.38 5.42 0.44 3.03e-7 Height; TGCT cis rs2153535 0.505 rs9405395 chr6:8468622 T/A cg07606381 chr6:8435919 SLC35B3 0.54 5.12 0.42 1.12e-6 Motion sickness; TGCT cis rs6121246 0.559 rs6121172 chr20:30296095 A/C cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs7336332 0.662 rs9581862 chr13:28039993 T/G cg22138327 chr13:27999177 GTF3A 0.73 5.63 0.45 1.13e-7 Weight; TGCT cis rs2404602 0.679 rs12899871 chr15:76757347 T/C cg26408565 chr15:76604113 ETFA -0.4 -5.26 -0.43 6.23e-7 Blood metabolite levels; TGCT cis rs9916302 0.904 rs7503705 chr17:37669704 A/G cg15445000 chr17:37608096 MED1 0.32 4.66 0.39 8.18e-6 Glomerular filtration rate (creatinine); TGCT cis rs35146811 0.735 rs2528900 chr7:99805319 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs600231 0.708 rs661403 chr11:65242478 A/G cg17120908 chr11:65337727 SSSCA1 -0.55 -5.14 -0.42 1.03e-6 Bone mineral density; TGCT cis rs875971 0.619 rs2302918 chr7:66000932 A/G cg00343986 chr7:65444356 GUSB 0.24 5.4 0.44 3.32e-7 Aortic root size; TGCT cis rs5769707 0.935 rs9616332 chr22:50047678 C/G cg20744362 chr22:50050164 C22orf34 0.29 4.82 0.4 4.12e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2295359 0.892 rs6688383 chr1:67655954 C/T cg12940439 chr1:67600707 NA -0.61 -6.3 -0.49 4.68e-9 Psoriasis; TGCT cis rs11031096 0.774 rs1867133 chr11:4205956 A/G cg18678763 chr11:4115507 RRM1 -0.4 -5.52 -0.44 1.9e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9929218 0.529 rs2296404 chr16:68729525 C/T cg01251360 chr16:68772225 CDH1 -0.26 -4.83 -0.4 3.87e-6 Colorectal cancer; TGCT cis rs57920188 0.658 rs7548273 chr1:4078945 G/C cg20703997 chr1:4087676 NA 0.46 5.72 0.46 7.63e-8 Interleukin-17 levels; TGCT cis rs7937612 1.000 rs2305010 chr11:120330149 C/G cg24566217 chr11:120254723 ARHGEF12 0.3 4.67 0.39 7.84e-6 Intraocular pressure; TGCT cis rs6815814 0.851 rs17582921 chr4:38892649 T/C cg02016764 chr4:38805732 TLR1 -0.34 -5.18 -0.42 8.61e-7 Breast cancer; TGCT cis rs7917772 0.502 rs10748827 chr10:104368336 G/T cg05855489 chr10:104503620 C10orf26 -0.61 -5.41 -0.44 3.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9467773 0.587 rs10946812 chr6:26344975 G/C cg15659132 chr6:26577336 NA -0.52 -5.32 -0.43 4.77e-7 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.567 rs6060263 chr20:30193110 T/C cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs12458462 0.787 rs56006341 chr18:77439844 G/T cg11879182 chr18:77439856 CTDP1 0.67 7.67 0.57 4.44e-12 Monocyte count; TGCT cis rs11785400 1.000 rs4327844 chr8:143733540 C/T cg24634471 chr8:143751801 JRK -0.53 -5.77 -0.46 5.94e-8 Schizophrenia; TGCT trans rs564343 0.583 rs2430978 chr11:65816656 G/C cg26701943 chr11:108369231 KDELC2 -0.71 -6.7 -0.52 6.5e-10 Obesity (early onset extreme); TGCT cis rs889312 0.500 rs702688 chr5:56190986 A/G cg24531977 chr5:56204891 C5orf35 -0.5 -5.04 -0.41 1.57e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs7819412 0.594 rs17724226 chr8:10968926 C/T cg21775007 chr8:11205619 TDH -0.49 -4.94 -0.41 2.5e-6 Triglycerides; TGCT cis rs4808199 0.895 rs12981405 chr19:19651577 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.73 4.89 0.4 3.05e-6 Nonalcoholic fatty liver disease; TGCT cis rs899997 1.000 rs11072793 chr15:79006442 C/T cg04896959 chr15:78267971 NA 0.33 5.12 0.42 1.13e-6 Coronary artery disease or large artery stroke; TGCT cis rs9902453 0.874 rs7213517 chr17:28401740 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.82 -7.84 -0.58 1.8e-12 Coffee consumption (cups per day); TGCT cis rs4499344 0.921 rs752718 chr19:33086262 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.6 -0.51 1.07e-9 Mean platelet volume; TGCT cis rs3845702 0.673 rs12468986 chr2:180862320 T/G cg01881094 chr2:180872142 CWC22 1.06 6.66 0.51 8.12e-10 Schizophrenia; TGCT cis rs6088580 0.634 rs6059890 chr20:33101653 G/C cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.51 4.72 0.39 6.37e-6 Schizophrenia; TGCT cis rs12188164 0.965 rs11745789 chr5:450777 T/C cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs765787 0.530 rs28414644 chr15:45536721 G/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs77633900 0.614 rs2439993 chr15:76861532 G/A cg21673338 chr15:77095150 SCAPER -0.5 -4.68 -0.39 7.27e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs17376456 0.877 rs12153788 chr5:93405437 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs6121246 0.909 rs6089058 chr20:30326338 T/G cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs295140 0.903 rs3820888 chr2:201180023 T/C cg04283868 chr2:201171347 SPATS2L 0.62 6.15 0.48 1e-8 QT interval; TGCT cis rs882300 0.934 rs2102895 chr2:136906692 G/A cg05194412 chr2:137003533 NA 0.24 4.59 0.38 1.06e-5 Multiple sclerosis;Electrocardiographic traits; TGCT cis rs6490294 0.861 rs2106956 chr12:112418918 C/T cg10833066 chr12:111807467 FAM109A 0.36 5.33 0.43 4.4e-7 Mean platelet volume; TGCT cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg04944784 chr2:26401820 FAM59B -0.78 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT cis rs34638657 0.500 rs1056675 chr16:82181934 T/C cg09439754 chr16:82129088 HSD17B2 -0.22 -4.59 -0.38 1.08e-5 Lung adenocarcinoma; TGCT cis rs4273100 0.688 rs4143829 chr17:19241505 G/A cg01534423 chr17:18965556 NA -0.79 -7.19 -0.54 5.25e-11 Schizophrenia; TGCT cis rs4808199 0.948 rs2301671 chr19:19466269 C/T cg03709012 chr19:19516395 GATAD2A 0.81 6.55 0.51 1.4e-9 Nonalcoholic fatty liver disease; TGCT cis rs9926296 0.586 rs1800359 chr16:89805261 A/G cg27121462 chr16:89883253 FANCA 0.57 5.32 0.43 4.64e-7 Vitiligo; TGCT cis rs7666738 0.830 rs10010698 chr4:98981594 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs7267979 1.000 rs2482911 chr20:25395528 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7786808 0.707 rs62479983 chr7:158227613 G/A cg01191920 chr7:158217561 PTPRN2 -0.43 -6.3 -0.49 4.68e-9 Obesity-related traits; TGCT cis rs12142240 0.730 rs56030283 chr1:46823093 C/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg03806693 chr22:41940476 POLR3H -1.12 -12.12 -0.74 8.54e-23 Crohn's disease;Inflammatory bowel disease; TGCT trans rs2688608 0.752 rs1916341 chr10:75671162 G/T cg13918328 chr10:52500089 ASAH2B 0.67 6.77 0.52 4.64e-10 Inflammatory bowel disease; TGCT cis rs875971 1.000 rs778696 chr7:65870813 C/G cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs35306767 0.953 rs1106064 chr10:957211 G/A cg26597838 chr10:835615 NA 0.66 9.01 0.63 3.04e-15 Eosinophil percentage of granulocytes; TGCT cis rs11105298 0.891 rs3825330 chr12:89933710 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.85 -0.4 3.63e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9300255 0.568 rs1621194 chr12:123651018 T/C cg00376283 chr12:123451042 ABCB9 0.72 5.55 0.45 1.65e-7 Neutrophil percentage of white cells; TGCT cis rs7017914 0.967 rs2732087 chr8:71860439 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -5.02 -0.41 1.72e-6 Bone mineral density; TGCT cis rs7584330 0.554 rs77180399 chr2:238442951 G/A cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs950776 0.752 rs62010328 chr15:78894971 C/T cg06917634 chr15:78832804 PSMA4 0.68 5.37 0.43 3.7e-7 Sudden cardiac arrest; TGCT cis rs704 0.585 rs1007398 chr17:26665648 A/G cg10494684 chr17:26645200 TMEM97 -0.45 -4.89 -0.4 3.03e-6 Osteoprotegerin levels; TGCT cis rs7552404 0.924 rs1146581 chr1:76213024 T/G cg03433033 chr1:76189801 ACADM 0.77 9.25 0.64 8.26e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4906332 0.933 rs34606394 chr14:103915636 G/A cg26031613 chr14:104095156 KLC1 -0.53 -4.72 -0.39 6.2e-6 Coronary artery disease; TGCT cis rs7216064 1.000 rs9912084 chr17:65868035 A/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7568458 0.811 rs3755014 chr2:85764006 C/T cg17127132 chr2:85788382 GGCX 0.68 6.58 0.51 1.18e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.33 4.77 0.39 5.17e-6 Schizophrenia; TGCT cis rs2730260 0.537 rs3793224 chr7:158876573 G/A cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs62103177 0.810 rs62103195 chr18:77629693 T/C cg12964065 chr18:77638022 KCNG2 0.38 4.76 0.39 5.2e-6 Opioid sensitivity; TGCT cis rs11577318 0.853 rs12728971 chr1:26626612 C/T cg04990556 chr1:26633338 UBXN11 -0.63 -5.83 -0.46 4.58e-8 Granulocyte percentage of myeloid white cells; TGCT trans rs1814175 0.647 rs2903409 chr11:49953612 C/G cg03929089 chr4:120376271 NA -0.62 -7.26 -0.55 3.76e-11 Height; TGCT cis rs2227564 0.620 rs11000787 chr10:75584383 T/C cg19442545 chr10:75533431 FUT11 -0.31 -4.47 -0.37 1.72e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7582180 0.676 rs10048665 chr2:100933085 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs7412746 0.658 rs7528773 chr1:150915875 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs2760061 0.626 rs635563 chr1:228136834 C/T cg02753203 chr1:228287806 NA -0.35 -6.84 -0.52 3.14e-10 Diastolic blood pressure; TGCT cis rs7020830 0.858 rs13293465 chr9:37127678 C/T cg14294708 chr9:37120828 ZCCHC7 1.26 17.63 0.85 1.37e-35 Schizophrenia; TGCT cis rs3824867 0.770 rs11820680 chr11:47452744 C/T cg20307385 chr11:47447363 PSMC3 -0.68 -5.78 -0.46 5.79e-8 Mean corpuscular hemoglobin; TGCT cis rs9435341 0.965 rs6669831 chr1:107608607 G/A cg09367891 chr1:107599246 PRMT6 -0.63 -5.48 -0.44 2.24e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs1697139 0.583 rs11739587 chr5:66540481 A/C cg11553311 chr5:66541588 NA -0.28 -5.96 -0.47 2.4e-8 Breast cancer; TGCT cis rs12142240 0.698 rs17361936 chr1:46862893 C/T cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs13064411 0.542 rs13082603 chr3:113223362 T/C cg18753928 chr3:113234510 CCDC52 -0.56 -4.72 -0.39 6.3e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7089973 0.604 rs17095662 chr10:116596071 A/C cg03647239 chr10:116582469 FAM160B1 0.58 5.66 0.45 9.75e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs2180341 0.960 rs1543432 chr6:127698018 T/C cg24812749 chr6:127587940 RNF146 0.99 7.63 0.57 5.24e-12 Breast cancer; TGCT cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg11644478 chr21:40555479 PSMG1 1.04 10.81 0.7 1.38e-19 Cognitive function; TGCT cis rs7666738 0.791 rs34437628 chr4:99029232 C/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.659 rs62541538 chr9:5038164 G/A cg02405213 chr9:5042618 JAK2 -0.77 -10.51 -0.69 7.18e-19 Pediatric autoimmune diseases; TGCT cis rs36022378 0.504 rs4688688 chr3:50042690 C/G cg03060546 chr3:49711283 APEH -0.57 -4.53 -0.38 1.37e-5 Diastolic blood pressure; TGCT cis rs7552404 0.690 rs2029681 chr1:76333846 G/A cg03433033 chr1:76189801 ACADM -0.59 -5.97 -0.47 2.34e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13256369 1.000 rs10103769 chr8:8573036 G/T cg17143192 chr8:8559678 CLDN23 0.62 5.82 0.46 4.82e-8 Obesity-related traits; TGCT cis rs13191362 0.935 rs35100164 chr6:162963003 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.17e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs8056742 0.818 rs9939283 chr16:85090195 C/G cg00229868 chr16:85520891 NA 0.34 5.07 0.41 1.42e-6 Amyotrophic lateral sclerosis; TGCT trans rs1814175 0.817 rs11518158 chr11:49985633 G/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.89e-11 Height; TGCT cis rs7267979 0.816 rs6037158 chr20:25595466 C/A cg03522245 chr20:25566470 NINL 0.56 5.74 0.46 6.77e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2404602 1.000 rs12898430 chr15:76874923 G/A cg26408565 chr15:76604113 ETFA -0.38 -4.82 -0.4 4.03e-6 Blood metabolite levels; TGCT cis rs8077577 1.000 rs62073606 chr17:18069142 G/A cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs17197710 0.608 rs41304347 chr11:47330991 A/G cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4975709 0.569 rs2077269 chr5:1863506 C/T cg15595755 chr5:1867978 NA 0.46 5.36 0.43 3.94e-7 Cardiovascular disease risk factors; TGCT cis rs6964587 0.692 rs10227225 chr7:91571074 A/G cg17063962 chr7:91808500 NA -0.75 -7.1 -0.54 8.63e-11 Breast cancer; TGCT cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg13695892 chr22:41940480 POLR3H 0.92 9.29 0.64 6.61e-16 Vitiligo; TGCT trans rs2469997 0.843 rs2470030 chr8:120368991 T/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs12142240 0.698 rs41534051 chr1:46828734 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.79 -0.4 4.69e-6 Menopause (age at onset); TGCT cis rs17331151 0.573 rs2276818 chr3:52864635 A/G cg12962167 chr3:53033115 SFMBT1 0.44 4.96 0.41 2.28e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1799949 0.929 rs799906 chr17:41278116 T/C cg10047753 chr17:41438598 NA 0.77 7.29 0.55 3.18e-11 Menopause (age at onset); TGCT cis rs12049351 0.524 rs4925495 chr1:229624424 C/T cg12130225 chr1:229698885 NA 0.39 4.55 0.38 1.24e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7727544 0.735 rs272884 chr5:131668654 G/C cg24060327 chr5:131705240 SLC22A5 -0.56 -6.31 -0.49 4.43e-9 Blood metabolite levels; TGCT cis rs8062405 1.000 rs8055982 chr16:28881202 A/C cg09754948 chr16:28834200 ATXN2L 0.6 4.46 0.37 1.79e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs10114408 0.918 rs10992944 chr9:96640702 A/G cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9906944 0.933 rs35051752 chr17:47089908 G/A cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.8 -0.4 4.47e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs6540559 0.673 rs11803382 chr1:209986426 G/A cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs10875746 0.903 rs11168418 chr12:48515754 C/A cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg24846343 chr22:24311635 DDTL 0.23 5.79 0.46 5.37e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs5750830 0.649 rs4821895 chr22:39823015 A/G cg02038168 chr22:39784481 NA -0.76 -6.33 -0.49 4.13e-9 Intelligence (multi-trait analysis); TGCT cis rs10838634 1.000 rs11824327 chr11:46864705 T/C cg18332754 chr11:46939436 LRP4 0.91 4.61 0.38 9.98e-6 Schizophrenia; TGCT cis rs1008375 0.932 rs4698630 chr4:17614692 C/G cg16339924 chr4:17578868 LAP3 0.74 5.88 0.47 3.64e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3806843 0.966 rs11958868 chr5:140201420 T/C cg19875535 chr5:140030758 IK 0.36 5.84 0.46 4.29e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs17253792 0.822 rs77599953 chr14:56058905 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs2439831 0.867 rs3213991 chr15:43670280 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg13732083 chr21:47605072 C21orf56 -0.35 -4.51 -0.38 1.5e-5 Testicular germ cell tumor; TGCT cis rs2455799 0.613 rs1393969 chr3:15730257 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.65e-6 Mean platelet volume; TGCT cis rs9926296 0.585 rs6500441 chr16:89828669 C/G cg26513180 chr16:89883248 FANCA 1.07 14.72 0.8 5.42e-29 Vitiligo; TGCT cis rs10114408 0.959 rs7857898 chr9:96642275 C/T cg13679303 chr9:96623674 NA -0.35 -4.45 -0.37 1.85e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs881375 0.933 rs7028641 chr9:123691141 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.99 0.41 2.03e-6 Rheumatoid arthritis; TGCT cis rs4786125 0.636 rs7192853 chr16:6918241 G/C cg03623568 chr16:6915990 A2BP1 -0.45 -6.66 -0.51 7.78e-10 Heart rate variability traits (SDNN); TGCT cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg06634786 chr22:41940651 POLR3H 0.89 8.4 0.6 8.56e-14 Vitiligo; TGCT cis rs7582180 0.629 rs4851308 chr2:100971865 C/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.38e-6 Intelligence (multi-trait analysis); TGCT cis rs918629 0.679 rs12055287 chr5:95272428 G/C cg16656078 chr5:95278638 ELL2 -0.32 -5.06 -0.41 1.49e-6 IgG glycosylation; TGCT cis rs72781680 0.768 rs56339558 chr2:24125234 G/A cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs7611238 0.560 rs62288364 chr3:195110699 C/A cg27323046 chr3:195102265 ACAP2 0.38 5.06 0.41 1.5e-6 Body mass index; TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg01802117 chr1:53393560 SCP2 -0.42 -5.25 -0.43 6.33e-7 Monocyte count; TGCT cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg01084871 chr4:1340883 KIAA1530 0.59 4.62 0.38 9.57e-6 Longevity; TGCT cis rs10465746 0.747 rs10493741 chr1:84388118 G/C cg10977910 chr1:84465055 TTLL7 0.71 7.15 0.54 6.64e-11 Obesity-related traits; TGCT trans rs9383153 0.590 rs2072736 chr6:16328068 T/C cg19402885 chr12:15475236 PTPRO 0.99 6.81 0.52 3.76e-10 Gambling; TGCT cis rs1005277 0.579 rs2505241 chr10:38442421 T/C cg13531842 chr10:38383804 ZNF37A -0.39 -4.65 -0.39 8.25e-6 Extrinsic epigenetic age acceleration; TGCT trans rs208520 0.690 rs1351867 chr6:66760995 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.29 0.71 9.4e-21 Exhaled nitric oxide output; TGCT cis rs79349575 0.783 rs11079844 chr17:47028334 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs17152411 0.895 rs7080330 chr10:126585673 A/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs4654899 0.833 rs3816454 chr1:21191416 T/G cg01072550 chr1:21505969 NA 0.46 6.86 0.52 2.89e-10 Superior frontal gyrus grey matter volume; TGCT cis rs853679 0.517 rs12332979 chr6:28141548 T/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7829975 0.684 rs474892 chr8:8596731 G/T cg15556689 chr8:8085844 FLJ10661 -0.62 -5.28 -0.43 5.55e-7 Mood instability; TGCT cis rs9911578 1.000 rs9898916 chr17:57048660 C/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.25 -0.49 6.03e-9 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.715 rs11130032 chr3:44704083 G/A cg15687855 chr3:44754131 ZNF502 -0.41 -4.78 -0.39 4.93e-6 Depressive symptoms; TGCT cis rs2188554 0.740 rs213944 chr7:117190066 C/T cg09181792 chr7:117119393 CFTR 0.47 4.47 0.37 1.77e-5 Esophageal adenocarcinoma; TGCT cis rs908922 0.962 rs4240882 chr1:152456358 G/C cg20991723 chr1:152506922 NA 0.42 5.35 0.43 4.14e-7 Hair morphology; TGCT cis rs3809863 0.602 rs7225700 chr17:45391804 T/C cg08085267 chr17:45401833 C17orf57 -0.66 -7.62 -0.56 5.77e-12 Glaucoma (primary open-angle); TGCT cis rs2730245 0.527 rs842693 chr7:158660491 C/T cg11984989 chr7:158649758 WDR60 1.01 7.8 0.57 2.2e-12 Height; TGCT cis rs6815814 0.950 rs67206233 chr4:38807853 T/C cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg13395646 chr4:1353034 KIAA1530 0.38 4.58 0.38 1.1e-5 Obesity-related traits; TGCT cis rs763121 0.962 rs138703 chr22:39132748 C/T cg06022373 chr22:39101656 GTPBP1 0.7 6.69 0.51 7e-10 Menopause (age at onset); TGCT cis rs875971 0.862 rs12537823 chr7:65720884 C/T cg11764359 chr7:65958608 NA 0.57 5.12 0.42 1.12e-6 Aortic root size; TGCT cis rs2932538 0.961 rs3795820 chr1:113163042 C/A cg10983938 chr1:113465962 AFARP1;SLC16A1 -0.21 -4.5 -0.37 1.52e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg21644426 chr2:191273491 MFSD6 -0.6 -5.91 -0.47 3.12e-8 Pulse pressure; TGCT cis rs1218582 0.772 rs10908445 chr1:154849590 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.59 6.16 0.48 9.39e-9 Prostate cancer; TGCT cis rs17376456 0.877 rs10065056 chr5:93380123 G/T cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs4862750 0.914 rs11945845 chr4:187874136 T/C cg11301795 chr4:187892539 NA -0.36 -5.38 -0.43 3.61e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg17328964 chr8:145687451 CYHR1 0.44 6.29 0.49 5.08e-9 Age at first birth; TGCT cis rs12478296 1.000 rs11899408 chr2:243014630 A/G cg06360820 chr2:242988706 NA -0.85 -6.23 -0.49 6.61e-9 Obesity-related traits; TGCT cis rs72945132 0.825 rs57871058 chr11:70192344 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg11905131 chr22:24372483 LOC391322 -0.95 -11.15 -0.71 2.06e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9926296 0.712 rs258332 chr16:89727683 G/A cg03388025 chr16:89894329 SPIRE2 -0.35 -5.09 -0.42 1.28e-6 Vitiligo; TGCT cis rs727505 0.954 rs68102397 chr7:124685315 C/T cg23710748 chr7:124431027 NA -0.27 -4.59 -0.38 1.08e-5 Lewy body disease; TGCT cis rs17270561 0.579 rs10456326 chr6:25919662 G/A cg17691542 chr6:26056736 HIST1H1C 0.89 6.28 0.49 5.3e-9 Iron status biomarkers; TGCT cis rs4975616 0.843 rs4975615 chr5:1315343 C/T cg07493874 chr5:1342172 CLPTM1L 0.25 6.05 0.48 1.58e-8 Lung cancer; TGCT cis rs801193 0.967 rs2707841 chr7:66157020 A/G cg18876405 chr7:65276391 NA 0.33 5.05 0.41 1.55e-6 Aortic root size; TGCT cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs9894429 0.789 rs6565611 chr17:79598319 T/C cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs11105306 1 rs11105306 chr12:89897388 C/T cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 NT-proBNP levels in acute coronary syndrome; TGCT cis rs7220401 0.789 rs4794859 chr17:27962393 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.15 -0.54 6.61e-11 Coronary artery disease; TGCT cis rs6988636 1.000 rs58177772 chr8:124188067 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs12510870 0.566 rs6837506 chr4:74462267 C/T cg05868023 chr4:75230803 EREG 0.56 5.01 0.41 1.83e-6 Iris color (b* coordinate); TGCT cis rs138249 0.505 rs138218 chr22:50547558 T/C cg24864161 chr22:50528282 MOV10L1 0.5 4.45 0.37 1.91e-5 Gestational age at birth in labor-initiated deliveries (child effect); TGCT trans rs1814175 0.727 rs2140597 chr11:49873946 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs9467773 1.000 rs9467791 chr6:26562486 A/G cg15659132 chr6:26577336 NA -0.88 -12.86 -0.76 1.43e-24 Intelligence (multi-trait analysis); TGCT cis rs2354432 0.607 rs6683243 chr1:146733422 A/T cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs477895 1.000 rs34292685 chr11:64049021 C/T cg04317338 chr11:64019027 PLCB3 0.7 5.65 0.45 1.05e-7 Mean platelet volume; TGCT cis rs909002 0.962 rs1474181 chr1:32136610 C/G cg11573219 chr1:32083031 HCRTR1 -0.36 -4.56 -0.38 1.2e-5 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.501 rs6751927 chr2:99740175 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.26 0.77 1.59e-25 Chronic sinus infection; TGCT cis rs8103278 0.507 rs10415988 chr19:46246704 C/T cg14061069 chr19:46274453 DMPK 0.62 10.19 0.68 4.35e-18 Coronary artery disease; TGCT cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs17030434 0.954 rs6847810 chr4:154752789 C/T cg14289246 chr4:154710475 SFRP2 -0.9 -7.03 -0.53 1.2e-10 Electrocardiographic conduction measures; TGCT cis rs2463822 0.844 rs2513737 chr11:62119495 G/C cg06239285 chr11:62104954 ASRGL1 0.92 6.75 0.52 5.06e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs734999 0.566 rs4648658 chr1:2560882 G/A cg18854424 chr1:2615690 NA -0.5 -5.95 -0.47 2.54e-8 Ulcerative colitis; TGCT cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.74 0.52 5.29e-10 Electroencephalogram traits; TGCT cis rs6988636 1.000 rs13261100 chr8:124190312 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs826838 0.967 rs4768330 chr12:39129399 T/C cg13010199 chr12:38710504 ALG10B -0.64 -5.11 -0.42 1.19e-6 Heart rate; TGCT cis rs9810089 0.711 rs711972 chr3:136110018 C/T cg12473912 chr3:136751656 NA 0.35 5.16 0.42 9.38e-7 Gestational age at birth (child effect); TGCT cis rs3771570 0.901 rs55764424 chr2:242407467 C/T cg21155796 chr2:242212141 HDLBP 0.92 6.63 0.51 9.25e-10 Prostate cancer; TGCT cis rs270601 0.770 rs1007602 chr5:131602166 T/C cg24060327 chr5:131705240 SLC22A5 -0.66 -6.85 -0.52 3.07e-10 Acylcarnitine levels; TGCT cis rs587847 0.597 rs28896807 chr15:37764378 A/G cg00216138 chr15:37171175 LOC145845 0.31 4.55 0.38 1.24e-5 Intraocular pressure; TGCT cis rs7267979 0.966 rs416745 chr20:25438868 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12368653 0.591 rs1552842 chr12:58012163 A/G cg00700412 chr12:58011837 NA -0.23 -4.62 -0.38 9.42e-6 Multiple sclerosis; TGCT cis rs2180341 0.695 rs6569487 chr6:127726196 C/T cg24812749 chr6:127587940 RNF146 -0.64 -5.82 -0.46 4.81e-8 Breast cancer; TGCT cis rs2255336 0.938 rs2733840 chr12:10545925 C/T cg16084090 chr12:10586130 KLRC2 0.28 4.62 0.38 9.32e-6 Blood protein levels; TGCT cis rs11673344 0.523 rs7245453 chr19:37534349 G/T cg08039142 chr19:36980659 ZNF566 0.51 4.69 0.39 6.99e-6 Obesity-related traits; TGCT cis rs2657888 1.000 rs28697089 chr12:56938703 A/G cg23002907 chr12:56915593 RBMS2 -0.45 -6.07 -0.48 1.44e-8 Adiponectin levels; TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg01802117 chr1:53393560 SCP2 -0.45 -5.73 -0.46 7.03e-8 Monocyte count; TGCT cis rs9291683 0.609 rs34709913 chr4:10028955 T/C cg00071950 chr4:10020882 SLC2A9 0.7 9.43 0.65 3.06e-16 Bone mineral density; TGCT cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs6089584 0.821 rs2273990 chr20:60579149 G/T cg06108461 chr20:60628389 TAF4 -0.59 -8.58 -0.61 3.35e-14 Body mass index; TGCT trans rs208520 1.000 rs72880045 chr6:66965232 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.88 8.21 0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs9486719 1.000 rs67996804 chr6:96884387 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs79349575 0.783 rs318090 chr17:46991752 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs77741769 0.529 rs3901854 chr12:121225526 C/T cg02419362 chr12:121203948 SPPL3 0.19 4.46 0.37 1.83e-5 Mean corpuscular volume; TGCT cis rs4950928 0.823 rs2153101 chr1:203168474 A/T cg17014757 chr1:203156097 CHI3L1 -0.36 -4.59 -0.38 1.09e-5 YKL-40 levels; TGCT cis rs737008 0.586 rs7195820 chr16:11403855 A/T cg00044050 chr16:11439710 C16orf75 0.62 4.44 0.37 1.93e-5 Obesity-related traits; TGCT cis rs10411936 1.000 rs873636 chr19:16514771 C/T cg14704714 chr19:15740395 CYP4F8 0.26 4.65 0.39 8.3e-6 White blood cell count;Multiple sclerosis; TGCT cis rs5758659 0.504 rs133367 chr22:42463366 A/G cg15557168 chr22:42548783 NA 0.22 5.74 0.46 6.78e-8 Cognitive function; TGCT cis rs4372836 0.964 rs55721532 chr2:28938968 A/G cg09522027 chr2:28974177 PPP1CB 0.59 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs9325144 0.647 rs12424190 chr12:39111206 A/T cg10518543 chr12:38710700 ALG10B -0.48 -4.5 -0.37 1.52e-5 Morning vs. evening chronotype; TGCT cis rs1635 0.655 rs2281041 chr6:28303845 G/C cg15743358 chr6:28303923 ZNF323 -1.28 -6.27 -0.49 5.57e-9 Schizophrenia; TGCT cis rs2046867 0.862 rs57396880 chr3:72844785 G/A cg25664220 chr3:72788482 NA -0.56 -7.05 -0.53 1.1e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg08859206 chr1:53392774 SCP2 -0.43 -6.56 -0.51 1.31e-9 Monocyte count; TGCT cis rs8177253 0.965 rs4854762 chr3:133499063 A/G cg08439880 chr3:133502540 NA 0.31 5.86 0.47 4e-8 Iron status biomarkers; TGCT cis rs62103177 0.733 rs62103193 chr18:77629217 C/T cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs295137 0.725 rs1729413 chr2:201086663 T/G cg23649088 chr2:200775458 C2orf69 0.29 5.16 0.42 9.7e-7 Asthma (bronchodilator response); TGCT cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs17270561 0.779 rs78589800 chr6:25883500 C/G cg17691542 chr6:26056736 HIST1H1C 0.87 6.0 0.47 2.02e-8 Iron status biomarkers; TGCT cis rs11690935 0.632 rs12052246 chr2:172895606 G/T cg13550731 chr2:172543902 DYNC1I2 0.6 5.28 0.43 5.59e-7 Schizophrenia; TGCT trans rs7086803 1.000 rs7086803 chr10:114498476 A/G cg12515325 chr1:110008909 SYPL2 -1.13 -6.73 -0.52 5.65e-10 Lung cancer; TGCT cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.97 0.41 2.15e-6 Height; TGCT cis rs3771570 1.000 rs62190370 chr2:242384194 C/G cg21155796 chr2:242212141 HDLBP 0.93 6.6 0.51 1.08e-9 Prostate cancer; TGCT cis rs4808199 0.948 rs7250368 chr19:19452763 G/A cg03709012 chr19:19516395 GATAD2A 0.81 6.55 0.51 1.4e-9 Nonalcoholic fatty liver disease; TGCT cis rs12541335 0.639 rs6993855 chr8:22163797 A/G cg07298985 chr8:22133076 PIWIL2 0.31 4.77 0.39 5.06e-6 Hypertriglyceridemia; TGCT cis rs3008870 0.677 rs2815354 chr1:67483642 A/T cg11518657 chr1:67396239 MIER1 0.61 4.81 0.4 4.26e-6 Lymphocyte percentage of white cells; TGCT cis rs11783469 0.524 rs4872139 chr8:23346641 A/G cg00472375 chr8:23315376 ENTPD4 0.75 5.72 0.46 7.44e-8 Reticulocyte count; TGCT cis rs586688 1.000 rs589855 chr1:201631649 C/A cg05779441 chr1:201574716 NA 0.28 4.6 0.38 1.03e-5 Obesity-related traits; TGCT cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg11279151 chr3:101281821 RG9MTD1 -0.45 -9.8 -0.66 3.86e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.816 rs6076358 chr20:25519403 G/T cg14121845 chr20:25566513 NINL -0.46 -4.76 -0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6831352 0.918 rs13112176 chr4:100055825 G/A cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.6e-6 Menopause (age at onset); TGCT cis rs2204008 0.539 rs2703682 chr12:38107969 A/G cg26384229 chr12:38710491 ALG10B 0.59 5.11 0.42 1.17e-6 Bladder cancer; TGCT cis rs9640161 0.702 rs3735175 chr7:150020457 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 8.98e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.17 -0.54 6.05e-11 Prostate cancer; TGCT cis rs17376456 1.000 rs34013242 chr5:93507947 C/T cg25358565 chr5:93447407 FAM172A 0.95 7.97 0.58 8.71e-13 Diabetic retinopathy; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg04234412 chr22:24373322 LOC391322 -0.9 -10.31 -0.68 2.18e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9311474 1.000 rs6445358 chr3:52308845 C/G cg10802521 chr3:52805072 NEK4 -0.58 -6.43 -0.5 2.45e-9 Electroencephalogram traits; TGCT cis rs35146811 0.735 rs2528900 chr7:99805319 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs6952809 0.884 rs60383982 chr7:2464394 T/G cg23289794 chr7:2394357 EIF3B -0.59 -4.78 -0.39 4.82e-6 Multiple sclerosis; TGCT cis rs10411936 0.962 rs2607278 chr19:16568197 C/T cg19006008 chr19:16999768 F2RL3 -0.27 -4.69 -0.39 7.07e-6 White blood cell count;Multiple sclerosis; TGCT cis rs7914558 0.966 rs10748835 chr10:104660256 C/T cg04362960 chr10:104952993 NT5C2 0.56 5.14 0.42 1.04e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2032447 0.613 rs6456708 chr6:26032847 G/C cg12310025 chr6:25882481 NA -0.49 -4.8 -0.4 4.53e-6 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.659 rs17822807 chr17:56687190 A/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs2742417 0.603 rs2742370 chr3:45782098 T/C cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs80282103 0.618 rs7100114 chr10:1110231 A/G cg08668510 chr10:1095578 IDI1 1.07 5.29 0.43 5.38e-7 Glomerular filtration rate (creatinine); TGCT cis rs1552244 0.515 rs7613004 chr3:9999913 A/C cg00149659 chr3:10157352 C3orf10 0.65 4.8 0.4 4.49e-6 Alzheimer's disease; TGCT cis rs9486719 1.000 rs3906199 chr6:97049899 C/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs8013055 0.796 rs35592422 chr14:105996593 G/C cg23356831 chr14:105996513 TMEM121 0.36 5.6 0.45 1.31e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs1215050 0.791 rs1669745 chr4:98842047 G/A cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.22e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4148883 0.689 rs1869458 chr4:100024728 C/G cg12011299 chr4:100065546 ADH4 0.37 5.69 0.46 8.58e-8 Alcohol dependence; TGCT cis rs7246967 0.673 rs12978964 chr19:22819244 G/A cg05241461 chr19:22816980 ZNF492 0.71 4.79 0.4 4.6e-6 Bronchopulmonary dysplasia; TGCT cis rs9467773 1.000 rs9467797 chr6:26568473 A/T cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs317689 0.819 rs317683 chr12:69713630 T/G cg14784868 chr12:69753453 YEATS4 0.58 4.96 0.41 2.25e-6 Response to diuretic therapy; TGCT cis rs7264396 0.635 rs2024854 chr20:34511189 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs9811920 0.666 rs793456 chr3:99525631 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.44 4.98 0.41 2.08e-6 Axial length; TGCT cis rs4631830 0.720 rs7090326 chr10:51503375 A/T cg10326726 chr10:51549505 MSMB -0.23 -4.51 -0.38 1.46e-5 Prostate-specific antigen levels; TGCT cis rs9372253 1.000 rs11153232 chr6:110716252 G/T cg00083206 chr6:110721305 DDO 0.43 6.46 0.5 2.2e-9 Platelet distribution width; TGCT cis rs6570726 1.000 rs455109 chr6:145872665 C/T cg23711669 chr6:146136114 FBXO30 0.71 6.66 0.51 7.78e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9486719 0.843 rs2205754 chr6:96843134 T/C cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs28595532 0.920 rs114165587 chr4:119779525 C/T cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs950027 0.620 rs2486274 chr15:45666228 G/T cg26924012 chr15:45694286 SPATA5L1 0.8 8.99 0.63 3.48e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs7945705 0.818 rs2742552 chr11:8876852 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -4.64 -0.38 8.82e-6 Hemoglobin concentration; TGCT cis rs1005277 0.579 rs2474594 chr10:38426661 G/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs9926296 0.712 rs459920 chr16:89730827 T/C cg27121462 chr16:89883253 FANCA -0.54 -5.01 -0.41 1.83e-6 Vitiligo; TGCT cis rs2046867 0.774 rs9820293 chr3:72876237 T/A cg25664220 chr3:72788482 NA -0.52 -5.95 -0.47 2.54e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs548987 0.529 rs6456703 chr6:25826119 C/T cg12310025 chr6:25882481 NA -0.57 -4.61 -0.38 9.67e-6 Homocysteine levels; TGCT cis rs8051431 0.876 rs8056712 chr16:72015406 A/G cg06353428 chr16:71660113 MARVELD3 0.55 4.76 0.39 5.3e-6 LDL cholesterol levels; TGCT cis rs4566357 0.557 rs6707158 chr2:227911269 A/G cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.92e-7 Coronary artery disease; TGCT cis rs6490294 0.583 rs7314282 chr12:112502438 A/G cg10833066 chr12:111807467 FAM109A 0.33 5.03 0.41 1.65e-6 Mean platelet volume; TGCT cis rs2836974 0.549 rs34160989 chr21:40554118 C/G cg11890956 chr21:40555474 PSMG1 0.95 7.14 0.54 6.84e-11 Cognitive function; TGCT cis rs9443645 0.901 rs1538235 chr6:79689450 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs10501293 0.703 rs4267059 chr11:42988930 T/G cg03447554 chr11:43094025 NA 0.44 6.45 0.5 2.25e-9 Cognitive performance; TGCT cis rs9500256 0.967 rs1012500 chr6:58304669 G/A cg16251399 chr6:58287822 GUSBL2 0.67 6.0 0.47 2.03e-8 Eosinophilic esophagitis (pediatric); TGCT cis rs7267979 0.899 rs2104734 chr20:25526668 A/G cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13108904 0.870 rs1564508 chr4:1244879 A/G cg03303774 chr4:1407052 NA 0.28 4.58 0.38 1.12e-5 Obesity-related traits; TGCT cis rs7267979 0.844 rs4423675 chr20:25402778 A/G cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6121246 0.697 rs6088857 chr20:30226764 G/C cg18721089 chr20:30220636 NA -0.53 -5.43 -0.44 2.86e-7 Mean corpuscular hemoglobin; TGCT cis rs2760061 0.819 rs1745417 chr1:228204279 C/T cg18477163 chr1:228402036 OBSCN 0.34 7.22 0.54 4.65e-11 Diastolic blood pressure; TGCT cis rs597539 0.652 rs579136 chr11:68637476 C/G cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2836974 0.666 rs4818015 chr21:40675493 A/C cg11890956 chr21:40555474 PSMG1 0.75 7.66 0.57 4.67e-12 Cognitive function; TGCT cis rs7552404 0.727 rs4949677 chr1:76266662 T/A cg03433033 chr1:76189801 ACADM 0.66 6.75 0.52 5.17e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg09904177 chr6:26538194 HMGN4 0.68 6.27 0.49 5.41e-9 Intelligence (multi-trait analysis); TGCT cis rs1541995 0.964 rs34992592 chr15:96380753 G/A cg00882281 chr15:96346592 NA 0.28 4.6 0.38 1.02e-5 Photic sneeze reflex; TGCT cis rs12477438 0.520 rs6741773 chr2:99738962 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.16 0.84 1.49e-34 Chronic sinus infection; TGCT cis rs3617 0.503 rs9866243 chr3:52915219 C/T cg11645453 chr3:52864694 ITIH4 -0.26 -5.07 -0.41 1.39e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1729951 0.575 rs747843 chr3:136703130 G/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs4148883 0.645 rs2851264 chr4:100029715 C/T cg12011299 chr4:100065546 ADH4 0.38 5.74 0.46 6.75e-8 Alcohol dependence; TGCT cis rs7017914 0.934 rs2639921 chr8:71874834 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.52 -4.84 -0.4 3.86e-6 Bone mineral density; TGCT cis rs877529 0.605 rs79504 chr22:39551555 T/C cg18708252 chr22:39545030 CBX7 -0.4 -5.85 -0.46 4.13e-8 Multiple myeloma; TGCT cis rs7027203 0.828 rs10761287 chr9:96609150 A/G cg13679303 chr9:96623674 NA -0.66 -10.78 -0.7 1.64e-19 DNA methylation (variation); TGCT cis rs9322193 0.923 rs62439842 chr6:149996983 G/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs9560113 0.580 rs9560115 chr13:112193619 G/A cg10483660 chr13:112241077 NA 0.32 4.64 0.38 8.8e-6 Menarche (age at onset); TGCT cis rs10254284 1.000 rs1985152 chr7:28166534 G/A cg23620719 chr7:28220237 JAZF1 -0.56 -4.87 -0.4 3.28e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs4654899 0.643 rs589755 chr1:21099846 A/G cg01072550 chr1:21505969 NA -0.54 -8.85 -0.62 7.62e-15 Superior frontal gyrus grey matter volume; TGCT cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg00343986 chr7:65444356 GUSB -0.22 -5.27 -0.43 5.79e-7 Calcium levels; TGCT cis rs892961 0.899 rs72896162 chr17:75412521 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs9948 0.786 rs62156225 chr2:97414118 T/C cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs12048904 0.541 rs1571046 chr1:101299216 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.87 7.77 0.57 2.6e-12 Multiple sclerosis; TGCT cis rs9811920 0.683 rs7650727 chr3:99688976 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.43 5.12 0.42 1.14e-6 Axial length; TGCT cis rs1008375 0.800 rs28754811 chr4:17612312 C/T cg10189774 chr4:17578691 LAP3 0.59 5.07 0.41 1.43e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7726839 0.540 rs12520279 chr5:657291 T/C cg25482853 chr8:67687455 SGK3 1.2 10.13 0.67 6.02e-18 Obesity-related traits; TGCT cis rs7617773 1.000 rs7617773 chr3:48193515 C/T cg11946769 chr3:48343235 NME6 -0.59 -5.25 -0.43 6.49e-7 Coronary artery disease; TGCT cis rs3796352 0.881 rs35385050 chr3:52997945 C/A cg15956490 chr3:53032818 SFMBT1 0.61 6.11 0.48 1.17e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs7647973 1.000 rs7647973 chr3:49510931 G/A cg07636037 chr3:49044803 WDR6 -0.73 -5.87 -0.47 3.65e-8 Menarche (age at onset); TGCT cis rs4319547 0.585 rs7953007 chr12:122816977 A/C cg05707623 chr12:122985044 ZCCHC8 -0.59 -4.53 -0.38 1.35e-5 Body mass index; TGCT cis rs10791097 0.748 rs2282579 chr11:130735482 C/T cg05962950 chr11:130786565 SNX19 0.89 11.4 0.72 4.96e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7666738 0.830 rs11944107 chr4:98931638 G/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 1.000 rs6546736 chr2:26293878 C/T cg25036284 chr2:26402008 FAM59B 0.57 4.97 0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg22920501 chr2:26401640 FAM59B 0.88 6.09 0.48 1.32e-8 Gut microbiome composition (summer); TGCT cis rs13185784 0.667 rs4441844 chr5:179645386 C/T cg04734276 chr5:178882605 NA 0.29 4.46 0.37 1.81e-5 TRAIL levels; TGCT cis rs6570726 0.764 rs448258 chr6:145869145 C/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6589563 0.737 rs57200947 chr11:116623674 C/T cg20660624 chr11:117307972 DSCAML1 -0.38 -4.99 -0.41 2.02e-6 Eosinophil counts; TGCT cis rs7681440 0.904 rs1442153 chr4:90775719 T/G cg14346243 chr4:90757452 SNCA -0.56 -5.47 -0.44 2.41e-7 Dementia with Lewy bodies; TGCT cis rs10510102 0.872 rs12244199 chr10:123724632 C/G cg23691251 chr10:123688108 ATE1 -0.67 -5.33 -0.43 4.38e-7 Breast cancer; TGCT cis rs9972944 0.902 rs9972956 chr17:63771092 T/C cg07283582 chr17:63770753 CCDC46 0.28 5.89 0.47 3.36e-8 Total body bone mineral density; TGCT cis rs739496 0.649 rs616513 chr12:112003383 G/T cg10833066 chr12:111807467 FAM109A 0.37 5.59 0.45 1.4e-7 Platelet count; TGCT trans rs3780486 0.718 rs73645257 chr9:33132354 C/T cg04842962 chr6:43655489 MRPS18A 0.99 7.15 0.54 6.6e-11 IgG glycosylation; TGCT cis rs1348850 0.632 rs11682717 chr2:178499240 C/G cg22681709 chr2:178499509 PDE11A -0.51 -6.43 -0.5 2.47e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs67311347 1.000 rs56992941 chr3:40472434 A/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs12971120 0.838 rs2241510 chr18:72180739 G/A cg26446133 chr18:72167187 CNDP2 -0.35 -5.95 -0.47 2.59e-8 Refractive error; TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.09 0.82 3.7e-32 Prudent dietary pattern; TGCT cis rs78487399 0.808 rs112387154 chr2:43763231 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.79 4.82 0.4 4.14e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10791097 0.547 rs11222371 chr11:130745719 C/T cg14779329 chr11:130786720 SNX19 0.29 4.79 0.4 4.58e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs926938 0.520 rs6663115 chr1:115272254 G/A cg12756093 chr1:115239321 AMPD1 -0.41 -4.93 -0.4 2.62e-6 Autism; TGCT cis rs11098499 1.000 rs28374891 chr4:120183550 G/A cg09307838 chr4:120376055 NA 0.49 4.52 0.38 1.43e-5 Corneal astigmatism; TGCT cis rs6815814 0.731 rs11096956 chr4:38776180 G/T cg02016764 chr4:38805732 TLR1 -0.29 -5.02 -0.41 1.73e-6 Breast cancer; TGCT cis rs259282 0.851 rs174083 chr19:33141180 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.88 9.84 0.66 3.09e-17 Schizophrenia; TGCT cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg09359103 chr1:154839909 KCNN3 -0.67 -12.98 -0.76 7.41e-25 Prostate cancer; TGCT cis rs2862064 0.818 rs1979870 chr5:156481383 T/C cg12943317 chr5:156479607 HAVCR1 -0.47 -5.98 -0.47 2.2e-8 Platelet count; TGCT cis rs911555 1.000 rs911552 chr14:103999508 A/G cg12935359 chr14:103987150 CKB 0.35 4.99 0.41 2.03e-6 Intelligence (multi-trait analysis); TGCT cis rs4886920 0.563 rs4509984 chr15:78079267 C/G cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs3008870 0.629 rs12742428 chr1:67426487 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.82 8.51 0.61 4.75e-14 Lymphocyte percentage of white cells; TGCT cis rs11098499 0.604 rs34278750 chr4:120571136 G/A cg09307838 chr4:120376055 NA 0.64 6.23 0.49 6.81e-9 Corneal astigmatism; TGCT cis rs7208859 0.623 rs8068645 chr17:29104342 T/A cg13385521 chr17:29058706 SUZ12P 0.8 4.71 0.39 6.51e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs804280 0.542 rs36100659 chr8:11791653 A/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Myopia (pathological); TGCT cis rs2070433 0.800 rs11700596 chr21:47874054 G/C cg12379764 chr21:47803548 PCNT 0.56 4.78 0.39 4.83e-6 Lymphocyte counts; TGCT cis rs28595532 0.920 rs17257039 chr4:119603703 G/A cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.66e-7 Cannabis dependence symptom count; TGCT cis rs7647973 0.626 rs1491985 chr3:49739507 G/C cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs548181 0.545 rs4486648 chr11:125610589 T/A cg03464685 chr11:125439445 EI24 -1.31 -7.98 -0.58 8.17e-13 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs904251 0.797 rs2776878 chr6:37487273 G/A cg08126542 chr6:37504118 NA -0.44 -5.94 -0.47 2.73e-8 Cognitive performance; TGCT cis rs9807989 0.507 rs1592458 chr2:103031749 A/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs1215050 0.605 rs4092341 chr4:98614252 C/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6500602 0.819 rs3747580 chr16:4455675 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.44 6.7 0.52 6.58e-10 Schizophrenia; TGCT cis rs11971779 0.680 rs4728467 chr7:139120562 G/A cg07862535 chr7:139043722 LUC7L2 0.69 5.41 0.44 3.1e-7 Diisocyanate-induced asthma; TGCT cis rs78487399 0.808 rs17039131 chr2:43652398 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.69 0.39 7.08e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2404602 0.692 rs12595586 chr15:77172210 A/G cg22467129 chr15:76604101 ETFA -0.47 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg27286337 chr10:134555280 INPP5A 0.45 5.43 0.44 2.8e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9611565 0.694 rs5758324 chr22:41787950 G/T cg06481639 chr22:41940642 POLR3H -0.58 -5.03 -0.41 1.67e-6 Vitiligo; TGCT cis rs10782582 0.609 rs2881785 chr1:76318096 T/C cg03433033 chr1:76189801 ACADM -0.52 -5.16 -0.42 9.66e-7 Daytime sleep phenotypes; TGCT cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.808 rs7561287 chr2:43689071 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -4.77 -0.39 4.98e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9393692 0.905 rs7747133 chr6:26293470 C/T cg05868516 chr6:26286170 HIST1H4H 0.63 5.93 0.47 2.76e-8 Educational attainment; TGCT cis rs4911259 0.552 rs11700082 chr20:31460244 A/G cg13636640 chr20:31349939 DNMT3B -0.89 -9.82 -0.66 3.4e-17 Inflammatory bowel disease; TGCT cis rs13392177 0.684 rs62185965 chr2:219073779 T/C cg00012203 chr2:219082015 ARPC2 -0.79 -8.02 -0.58 6.73e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs7923609 0.811 rs3847326 chr10:65331859 A/G cg08743896 chr10:65200160 JMJD1C 0.32 4.44 0.37 1.99e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2439831 0.850 rs3759790 chr15:44121030 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs593982 1.000 rs72922786 chr11:65562852 G/C cg08755490 chr11:65554678 OVOL1 -1.09 -7.12 -0.54 7.54e-11 Atopic dermatitis; TGCT cis rs79996792 0.578 rs77427002 chr2:162285739 T/C cg22496339 chr2:162101262 NA 0.54 4.46 0.37 1.81e-5 Neuroticism; TGCT cis rs6540559 0.673 rs58637469 chr1:209971480 T/A cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT cis rs7524258 0.835 rs7521425 chr1:7306543 C/T cg07173049 chr1:7289937 CAMTA1 0.29 4.72 0.39 6.23e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7412746 0.622 rs11552229 chr1:150783985 T/C cg04414720 chr1:150670196 GOLPH3L 0.42 5.25 0.43 6.37e-7 Melanoma; TGCT cis rs10984561 0.881 rs59676902 chr9:122252850 A/C cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs2295359 0.892 rs72676069 chr1:67658954 T/C cg08029281 chr1:67600428 NA 0.4 4.68 0.39 7.36e-6 Psoriasis; TGCT cis rs4478858 0.647 rs7524117 chr1:31738416 A/G cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs9467711 0.516 rs1165163 chr6:25863487 G/C cg12310025 chr6:25882481 NA -0.72 -4.77 -0.39 5.17e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4888262 0.545 rs4888270 chr16:74698576 A/G cg01733217 chr16:74700730 RFWD3 0.75 7.65 0.57 4.96e-12 Testicular germ cell tumor; TGCT cis rs7659604 0.539 rs11098645 chr4:122729251 G/A cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.23e-7 Type 2 diabetes; TGCT cis rs769267 0.965 rs2269873 chr19:19392401 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs7617773 0.780 rs7645425 chr3:48362369 A/T cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs1784581 0.631 rs3016544 chr6:162393065 T/C cg17173639 chr6:162384350 PARK2 -0.46 -8.18 -0.59 2.92e-13 Itch intensity from mosquito bite; TGCT cis rs6882046 0.513 rs676096 chr5:88035887 C/T cg22951263 chr5:87985283 NA -0.55 -5.94 -0.47 2.74e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2153535 0.580 rs9392223 chr6:8468650 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.8 0.46 5.19e-8 Motion sickness; TGCT trans rs7618501 0.633 rs2856234 chr3:50139142 A/G cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.624 rs76574510 chr4:9953252 T/A cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8014204 0.816 rs10083386 chr14:75347585 C/A cg06637938 chr14:75390232 RPS6KL1 -0.53 -4.58 -0.38 1.12e-5 Caffeine consumption; TGCT cis rs7267979 1.000 rs6083809 chr20:25329309 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5750830 0.649 rs5750808 chr22:39790987 G/A cg11247378 chr22:39784982 NA -0.74 -9.64 -0.65 9.38e-17 Intelligence (multi-trait analysis); TGCT cis rs8180040 0.676 rs7633698 chr3:47013452 A/T cg27129171 chr3:47204927 SETD2 0.73 9.4 0.65 3.57e-16 Colorectal cancer; TGCT cis rs9467711 0.606 rs71557334 chr6:26365913 G/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs295140 0.837 rs12474914 chr2:201130210 A/G cg04283868 chr2:201171347 SPATS2L 0.52 5.2 0.42 8.14e-7 QT interval; TGCT cis rs12477438 0.765 rs13390672 chr2:99589829 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs4819052 0.851 rs8127834 chr21:46696109 G/A cg06618935 chr21:46677482 NA -0.36 -5.58 -0.45 1.46e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2120019 1.000 rs12898259 chr15:75369780 G/A cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs7666738 0.830 rs13112131 chr4:98976784 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.764 rs7745696 chr6:146162829 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.61e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs17539620 0.519 rs871071 chr6:154837667 T/C cg20019720 chr6:154832845 CNKSR3 0.63 5.72 0.46 7.47e-8 Lipoprotein (a) levels; TGCT cis rs6988636 0.710 rs62521806 chr8:124161054 C/T cg23067535 chr8:124195133 FAM83A -0.35 -4.75 -0.39 5.61e-6 Urinary uromodulin levels; TGCT cis rs9549260 0.753 rs9549254 chr13:41234763 G/A cg21288729 chr13:41239152 FOXO1 0.67 4.78 0.39 4.78e-6 Red blood cell count; TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs4788570 0.566 rs10468265 chr16:71476943 T/C cg06353428 chr16:71660113 MARVELD3 -1.32 -7.86 -0.58 1.6e-12 Intelligence (multi-trait analysis); TGCT cis rs12643440 0.538 rs1581402 chr4:17139877 T/A cg22650099 chr4:17144496 NA -0.45 -4.65 -0.39 8.28e-6 Metabolite levels (Pyroglutamine); TGCT cis rs172166 0.694 rs2791332 chr6:28108788 C/T cg10876282 chr6:28092338 ZSCAN16 0.49 4.44 0.37 1.98e-5 Cardiac Troponin-T levels; TGCT cis rs7772486 0.686 rs4896833 chr6:145965673 T/G cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7043114 0.525 rs7863406 chr9:95053381 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.57 -0.45 1.53e-7 Height; TGCT cis rs6088580 0.602 rs6059834 chr20:33019299 A/G cg06115741 chr20:33292138 TP53INP2 0.55 4.81 0.4 4.24e-6 Glomerular filtration rate (creatinine); TGCT cis rs17601876 0.814 rs749292 chr15:51558731 A/G cg19946085 chr15:51559439 CYP19A1 0.33 5.04 0.41 1.6e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs1903068 0.925 rs1551645 chr4:55994314 T/G cg16572876 chr4:56024045 NA 0.45 5.08 0.42 1.34e-6 Endometriosis; TGCT cis rs1466788 0.965 rs1390954 chr1:110615668 C/T cg11787288 chr1:111506544 C1orf103 0.49 4.5 0.38 1.51e-5 Blood metabolite levels; TGCT cis rs9814567 0.806 rs9857242 chr3:134316378 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.76 7.2 0.54 5.12e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6901004 0.712 rs367734 chr6:111512378 C/G cg15721981 chr6:111408429 SLC16A10 -0.52 -4.6 -0.38 1.03e-5 Blood metabolite levels; TGCT cis rs2153535 0.541 rs1414347 chr6:8471831 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.07 0.41 1.43e-6 Motion sickness; TGCT cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs941408 1.000 rs941408 chr19:2814181 C/T cg06609049 chr19:2785107 THOP1 0.82 7.25 0.55 3.85e-11 Total cholesterol levels; TGCT cis rs1670533 1.000 rs7669622 chr4:1058659 A/G cg27284194 chr4:1044797 NA 0.66 5.69 0.45 8.85e-8 Recombination rate (females); TGCT cis rs137699 0.652 rs137707 chr22:39751401 T/C cg01416388 chr22:39784598 NA -0.59 -4.73 -0.39 6.08e-6 IgG glycosylation; TGCT cis rs62244186 0.715 rs10212378 chr3:44667286 C/G cg21672276 chr3:44754072 ZNF502 -0.43 -4.8 -0.4 4.44e-6 Depressive symptoms; TGCT cis rs7909074 1.000 rs7909074 chr10:45395839 G/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.33 -0.43 4.38e-7 Mean corpuscular volume; TGCT cis rs9325144 0.560 rs10785573 chr12:38654166 G/A cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs5750830 0.594 rs1010169 chr22:39778167 C/T cg11247378 chr22:39784982 NA 0.66 8.83 0.62 8.17e-15 Intelligence (multi-trait analysis); TGCT cis rs1451375 0.527 rs6950777 chr7:50597056 G/A cg18232548 chr7:50535776 DDC 0.35 4.64 0.38 8.75e-6 Malaria; TGCT cis rs2594989 0.622 rs2442794 chr3:11551001 A/G cg00170343 chr3:11313890 ATG7 0.62 4.46 0.37 1.79e-5 Circulating chemerin levels; TGCT cis rs6430585 0.591 rs61187091 chr2:136468238 G/A cg07169764 chr2:136633963 MCM6 1.12 10.49 0.69 8.04e-19 Corneal structure; TGCT cis rs10893109 1.000 rs10893109 chr11:123804419 A/C cg14126608 chr11:122846540 NA -0.28 -4.58 -0.38 1.12e-5 Facial morphology (factor 13, vertical position of alar curvature relative to upper lip); TGCT cis rs801193 0.660 rs974239 chr7:66213491 G/A cg11764359 chr7:65958608 NA 0.59 5.06 0.41 1.5e-6 Aortic root size; TGCT cis rs6484504 0.576 rs2150213 chr11:31244634 A/G cg14844989 chr11:31128820 NA -0.23 -4.44 -0.37 1.97e-5 Red blood cell count; TGCT cis rs17221829 0.627 rs12421880 chr11:89391713 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.47 -0.37 1.76e-5 Bipolar disorder; TGCT cis rs56011263 0.687 rs4690188 chr4:703930 G/C cg20735989 chr4:730612 PCGF3 -0.25 -5.45 -0.44 2.63e-7 White blood cell count; TGCT cis rs6088590 1.000 rs2378256 chr20:33292127 G/C cg24642439 chr20:33292090 TP53INP2 0.7 6.41 0.5 2.75e-9 Coronary artery disease; TGCT cis rs9814567 1.000 rs9850015 chr3:134269541 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.89 -0.66 2.32e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6815814 0.950 rs73236618 chr4:38794041 T/C cg02016764 chr4:38805732 TLR1 -0.32 -4.95 -0.41 2.35e-6 Breast cancer; TGCT cis rs9291683 0.605 rs73224439 chr4:10331818 C/A cg00071950 chr4:10020882 SLC2A9 -0.44 -4.53 -0.38 1.35e-5 Bone mineral density; TGCT cis rs9549367 0.826 rs2302755 chr13:113898418 C/T cg00898013 chr13:113819073 PROZ -0.43 -5.47 -0.44 2.37e-7 Platelet distribution width; TGCT cis rs35306767 0.855 rs34318754 chr10:890714 G/A cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.91 -10.9 -0.7 8.24e-20 Colorectal cancer; TGCT trans rs916888 0.821 rs415430 chr17:44859144 C/T cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8177253 1.000 rs6762719 chr3:133480817 A/G cg01448562 chr3:133502909 NA -0.33 -6.71 -0.52 6.3e-10 Iron status biomarkers; TGCT cis rs4566357 0.576 rs3769644 chr2:227917240 C/G cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg04267008 chr7:1944627 MAD1L1 -0.36 -4.76 -0.39 5.32e-6 Bipolar disorder and schizophrenia; TGCT cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg04267008 chr7:1944627 MAD1L1 -0.4 -5.46 -0.44 2.5e-7 Bipolar disorder and schizophrenia; TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs6840360 1.000 rs6838966 chr4:152603475 C/T cg17479576 chr4:152424074 FAM160A1 -0.49 -5.15 -0.42 9.73e-7 Intelligence (multi-trait analysis); TGCT cis rs793571 0.523 rs7163162 chr15:58983588 T/A cg05156742 chr15:59063176 FAM63B 0.48 4.46 0.37 1.83e-5 Schizophrenia; TGCT cis rs2334880 0.678 rs12919092 chr16:71446490 T/C cg06353428 chr16:71660113 MARVELD3 -1.23 -7.7 -0.57 3.78e-12 Malaria; TGCT cis rs7937682 0.924 rs875258 chr11:111530607 C/A cg09085632 chr11:111637200 PPP2R1B -1.12 -11.81 -0.73 4.86e-22 Primary sclerosing cholangitis; TGCT trans rs1814175 0.781 rs2866734 chr11:49886338 A/G cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs2224391 0.590 rs2145372 chr6:5245070 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.98 -6.21 -0.49 7.43e-9 Height; TGCT cis rs12681288 0.862 rs2701899 chr8:1019581 G/A cg04851639 chr8:1020857 NA -0.4 -7.59 -0.56 6.62e-12 Schizophrenia; TGCT cis rs3087591 0.960 rs4795587 chr17:29587917 A/C cg24425628 chr17:29625626 OMG;NF1 -0.49 -7.37 -0.55 2.06e-11 Hip circumference; TGCT cis rs9902453 0.808 rs56088359 chr17:28173659 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs896854 0.654 rs896846 chr8:95972453 G/A cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.07e-9 Type 2 diabetes; TGCT cis rs7666738 0.800 rs2839836 chr4:98970512 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7027203 0.828 rs3957506 chr9:96588133 C/T cg13679303 chr9:96623674 NA -0.68 -10.87 -0.7 9.9e-20 DNA methylation (variation); TGCT cis rs7267979 0.789 rs9927 chr20:25277244 A/G cg16686733 chr20:25566563 NINL 0.57 5.45 0.44 2.6e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs561341 1.000 rs546519 chr17:30297682 T/G cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs2797160 1.000 rs1418948 chr6:126007018 C/T cg05901451 chr6:126070800 HEY2 0.74 6.3 0.49 4.62e-9 Endometrial cancer; TGCT cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg04267008 chr7:1944627 MAD1L1 -0.4 -5.28 -0.43 5.67e-7 Bipolar disorder and schizophrenia; TGCT cis rs2692947 0.696 rs2969490 chr2:96803904 A/G cg22654517 chr2:96458247 NA 0.22 5.01 0.41 1.82e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg03264133 chr6:25882463 NA 0.5 5.29 0.43 5.3e-7 Blood metabolite levels; TGCT cis rs2506155 0.752 rs61843160 chr10:33515868 C/G cg25928881 chr10:32632685 EPC1 0.31 4.69 0.39 7.08e-6 Migraine; TGCT cis rs35146811 0.555 rs1981550 chr7:99541952 G/A cg13334819 chr7:99746414 C7orf59 -0.6 -5.1 -0.42 1.26e-6 Coronary artery disease; TGCT cis rs910316 1.000 rs4903284 chr14:75592483 G/C cg11812906 chr14:75593930 NEK9 0.73 7.23 0.54 4.36e-11 Height; TGCT cis rs6684514 1.000 rs2296375 chr1:156309372 G/C cg16558208 chr1:156270281 VHLL 0.48 9.38 0.64 4.04e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs3733631 0.696 rs7672658 chr4:104631530 G/A cg24090629 chr4:104641072 TACR3 -0.73 -5.81 -0.46 4.96e-8 Menarche (age at onset); TGCT cis rs34014631 1.000 rs78134907 chr10:103652875 T/G cg22630918 chr10:102748988 C10orf2 0.42 4.82 0.4 4.15e-6 Coronary artery calcification; TGCT cis rs6840360 0.554 rs62329088 chr4:152471289 C/T cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs6879260 1.000 rs1035411 chr5:179729519 A/G cg13944838 chr5:179740914 GFPT2 -0.41 -6.61 -0.51 1.03e-9 Height; TGCT cis rs35934224 0.783 rs35969236 chr22:19860355 T/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.04e-7 Glaucoma (primary open-angle); TGCT cis rs4072705 0.869 rs2416951 chr9:127550603 C/G cg13476313 chr9:127244764 NR5A1 0.29 4.79 0.4 4.63e-6 Menarche (age at onset); TGCT cis rs10504229 0.683 rs73603877 chr8:58108428 C/T cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT trans rs7618501 0.633 rs4688755 chr3:50064424 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.41 -0.65 3.39e-16 Intelligence (multi-trait analysis); TGCT cis rs12134133 1.000 rs7532664 chr1:207426943 C/T cg02152968 chr1:207494213 CD55 0.61 4.83 0.4 3.92e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg10883421 chr6:151773342 RMND1;C6orf211 0.81 9.15 0.63 1.44e-15 Menarche (age at onset); TGCT cis rs2836974 0.644 rs719230 chr21:40676307 C/T cg11890956 chr21:40555474 PSMG1 -0.73 -7.16 -0.54 6.37e-11 Cognitive function; TGCT cis rs3806843 0.838 rs2563289 chr5:140122766 T/A cg19875535 chr5:140030758 IK -0.35 -5.92 -0.47 2.89e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs875971 0.660 rs12698534 chr7:65986845 C/T cg00343986 chr7:65444356 GUSB 0.23 5.16 0.42 9.66e-7 Aortic root size; TGCT cis rs10992471 0.631 rs2296667 chr9:95274338 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -5.4 -0.44 3.31e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10883723 0.773 rs2296578 chr10:104240974 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7615952 0.866 rs11922276 chr3:125631326 G/T cg05084668 chr3:125655381 ALG1L -0.74 -6.05 -0.48 1.6e-8 Blood pressure (smoking interaction); TGCT cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg07617317 chr6:118971624 C6orf204 -0.49 -5.1 -0.42 1.26e-6 Diastolic blood pressure; TGCT cis rs10193935 0.901 rs7570083 chr2:42517859 G/A cg27598129 chr2:42591480 NA -0.39 -5.37 -0.43 3.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg18402987 chr7:1209562 NA 0.74 6.21 0.49 7.23e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs877282 1.000 rs71491304 chr10:772982 C/T cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs9325144 0.671 rs35817541 chr12:38975001 T/C cg26384229 chr12:38710491 ALG10B -0.59 -5.6 -0.45 1.28e-7 Morning vs. evening chronotype; TGCT cis rs9916302 0.904 rs4239222 chr17:37696235 A/C cg15445000 chr17:37608096 MED1 -0.36 -5.21 -0.42 7.58e-7 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.546 rs13141117 chr4:98892798 G/A cg05340658 chr4:99064831 C4orf37 0.59 6.33 0.49 4.05e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7582180 0.764 rs11682748 chr2:100925934 C/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs9858542 0.953 rs9827708 chr3:49649989 C/G cg03060546 chr3:49711283 APEH -0.63 -5.51 -0.44 1.96e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs853679 0.517 rs1947862 chr6:28105196 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs2153535 0.580 rs7747306 chr6:8453663 C/G cg23788917 chr6:8435910 SLC35B3 -0.62 -5.66 -0.45 9.91e-8 Motion sickness; TGCT cis rs28595532 0.668 rs72670237 chr4:119320937 T/C cg21605333 chr4:119757512 SEC24D 0.84 4.92 0.4 2.74e-6 Cannabis dependence symptom count; TGCT cis rs875971 0.755 rs10228885 chr7:65780529 C/G cg11764359 chr7:65958608 NA -0.55 -5.0 -0.41 1.94e-6 Aortic root size; TGCT cis rs2836633 0.895 rs2836597 chr21:40024424 A/G cg05519781 chr21:40033154 ERG 0.69 6.7 0.52 6.55e-10 Coronary artery disease; TGCT cis rs4455778 0.600 rs12718312 chr7:49024757 C/T cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs78545713 1.000 rs16891484 chr6:26242930 G/A cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.66 -4.71 -0.39 6.57e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs35264875 0.950 rs72928659 chr11:68852358 C/T cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs511515 1 rs511515 chr6:33541507 A/G cg24505687 chr6:33548425 BAK1 0.55 6.24 0.49 6.3e-9 Eosinophil counts;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs2841277 0.708 rs28600075 chr14:105408315 T/C cg19901468 chr14:105411992 AHNAK2 -0.27 -5.86 -0.47 3.84e-8 Rheumatoid arthritis; TGCT cis rs9393692 0.905 rs9379843 chr6:26289435 A/G cg05868516 chr6:26286170 HIST1H4H 0.63 5.88 0.47 3.57e-8 Educational attainment; TGCT trans rs7342694 0.965 rs12102309 chr16:81907046 T/C cg04928372 chr6:27720905 NA 0.7 6.79 0.52 4.18e-10 Coronary artery disease; TGCT cis rs7542091 0.669 rs7540534 chr1:210044824 A/T cg22029157 chr1:209979665 IRF6 0.64 6.1 0.48 1.23e-8 Monobrow; TGCT cis rs3008870 0.755 rs11208974 chr1:67398119 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.29 0.6 1.59e-13 Lymphocyte percentage of white cells; TGCT cis rs7726839 0.540 rs74553517 chr5:665671 C/T cg20362242 chr5:692897 TPPP 0.51 4.66 0.39 8.11e-6 Obesity-related traits; TGCT cis rs9911578 0.817 rs304264 chr17:56749628 A/G cg12560992 chr17:57184187 TRIM37 0.71 8.43 0.6 7.36e-14 Intelligence (multi-trait analysis); TGCT cis rs2180341 1.000 rs9285460 chr6:127640190 A/G cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs4938534 0.785 rs1944926 chr11:111287287 T/G cg01212326 chr11:111250286 POU2AF1 -0.23 -4.83 -0.4 3.94e-6 Primary biliary cholangitis; TGCT cis rs763121 0.657 rs5995603 chr22:39040733 G/A cg06022373 chr22:39101656 GTPBP1 0.73 6.34 0.49 3.9e-9 Menopause (age at onset); TGCT cis rs4805272 0.512 rs66830923 chr19:29321277 C/T cg03161606 chr19:29218774 NA 0.54 4.48 0.37 1.68e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs6754311 0.678 rs309181 chr2:136614813 C/G cg07169764 chr2:136633963 MCM6 -0.62 -5.74 -0.46 7e-8 Mosquito bite size; TGCT cis rs4975709 0.569 rs1684965 chr5:1865248 A/G cg15595755 chr5:1867978 NA 0.48 5.68 0.45 9.07e-8 Cardiovascular disease risk factors; TGCT trans rs62103177 0.561 rs891489 chr18:77637493 G/A cg05926928 chr17:57297772 GDPD1 -0.99 -9.29 -0.64 6.5e-16 Opioid sensitivity; TGCT cis rs2637266 1.000 rs2579747 chr10:78327759 C/T cg18941641 chr10:78392320 NA 0.39 4.97 0.41 2.16e-6 Pulmonary function; TGCT cis rs732765 0.734 rs12897105 chr14:75188122 G/T cg06637938 chr14:75390232 RPS6KL1 -0.55 -4.48 -0.37 1.71e-5 Non-small cell lung cancer; TGCT cis rs7659604 0.539 rs3217771 chr4:122739483 G/A cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.24e-7 Type 2 diabetes; TGCT cis rs2677744 1.000 rs4773 chr15:91463842 G/A cg22288577 chr15:91498497 RCCD1 0.47 4.86 0.4 3.45e-6 Attention deficit hyperactivity disorder; TGCT cis rs6461049 0.646 rs3778970 chr7:2143208 C/A cg04267008 chr7:1944627 MAD1L1 -0.35 -4.72 -0.39 6.16e-6 Schizophrenia; TGCT cis rs611744 0.967 rs598477 chr8:109187874 G/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs514475 0.526 rs12201688 chr6:137956658 T/G cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs9346649 0.606 rs6940383 chr6:168491688 G/A cg02770688 chr6:168491649 NA 0.32 5.58 0.45 1.41e-7 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs826838 0.967 rs1684414 chr12:39129553 A/G cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg03517284 chr6:25882590 NA -0.63 -6.91 -0.53 2.21e-10 Blood metabolite levels; TGCT cis rs8026198 0.734 rs7163986 chr15:42696158 A/T cg23803468 chr15:43513504 EPB42 0.28 4.57 0.38 1.16e-5 Fibrinogen levels; TGCT cis rs7833790 0.963 rs1451997 chr8:82774053 A/T cg06027949 chr8:82754900 SNX16 0.65 4.49 0.37 1.59e-5 Diastolic blood pressure; TGCT cis rs2439831 0.681 rs7168940 chr15:43633334 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 9.01 0.63 3.09e-15 Lung cancer in ever smokers; TGCT cis rs4918072 0.917 rs17573075 chr10:105649940 C/G cg11005552 chr10:105648138 OBFC1 0.42 5.41 0.44 3.17e-7 Coronary artery disease; TGCT cis rs5769707 0.935 rs1109320 chr22:49989106 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.59 0.38 1.06e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs28785552 0.931 rs8112235 chr19:53239010 C/G cg10871876 chr19:53194124 ZNF83 0.6 8.52 0.61 4.57e-14 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs9611565 0.879 rs4820437 chr22:41761290 T/C cg17554472 chr22:41940697 POLR3H -0.45 -4.91 -0.4 2.84e-6 Vitiligo; TGCT cis rs7917772 0.636 rs7897384 chr10:104529042 T/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.57 -4.71 -0.39 6.53e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2228479 0.850 rs2286393 chr16:89809548 C/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs4969178 0.645 rs4490057 chr17:76375095 C/T cg05887092 chr17:76393375 PGS1 -0.22 -4.85 -0.4 3.7e-6 HDL cholesterol levels; TGCT cis rs782590 0.967 rs58003472 chr2:55797507 T/C cg03859395 chr2:55845619 SMEK2 0.92 11.37 0.71 5.88e-21 Metabolic syndrome; TGCT cis rs6570726 0.738 rs7746330 chr6:145899257 A/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.58 -0.38 1.13e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.875 rs2073287 chr6:146350264 T/C cg23711669 chr6:146136114 FBXO30 0.85 9.44 0.65 2.92e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs478222 1.000 rs478222 chr2:25301755 A/T cg01884057 chr2:25150051 NA -0.25 -4.64 -0.38 8.56e-6 Type 1 diabetes; TGCT cis rs75686122 0.772 rs78015094 chr8:104587409 C/T cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs4654899 0.627 rs667071 chr1:21045726 T/C cg01072550 chr1:21505969 NA -0.4 -5.96 -0.47 2.45e-8 Superior frontal gyrus grey matter volume; TGCT cis rs854765 0.534 rs7207461 chr17:17949789 T/G cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs7552404 1.000 rs28602663 chr1:76235355 C/T cg03433033 chr1:76189801 ACADM 0.82 9.39 0.64 3.73e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1215050 0.740 rs783932 chr4:98973936 C/G cg17366294 chr4:99064904 C4orf37 -0.55 -5.8 -0.46 5.23e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7523273 0.606 rs7144 chr1:207967719 A/G cg22525895 chr1:207977042 MIR29B2 -0.57 -10.0 -0.67 1.3e-17 Schizophrenia; TGCT cis rs10411936 1.000 rs16995422 chr19:16519045 A/G cg14704714 chr19:15740395 CYP4F8 -0.26 -4.57 -0.38 1.16e-5 White blood cell count;Multiple sclerosis; TGCT cis rs62380364 0.754 rs4518438 chr5:88157552 T/C cg22951263 chr5:87985283 NA -0.51 -5.01 -0.41 1.85e-6 Intelligence (multi-trait analysis); TGCT cis rs10875746 0.903 rs11168414 chr12:48512331 C/T cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs10804591 0.848 rs4579013 chr3:129316019 G/C cg07730360 chr3:128845626 NA -0.2 -4.53 -0.38 1.37e-5 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9457247 1.000 rs2769354 chr6:167379771 G/T cg25258033 chr6:167368657 RNASET2 -0.18 -4.49 -0.37 1.63e-5 Crohn's disease; TGCT cis rs2282802 0.651 rs10060071 chr5:139599097 T/C cg01081189 chr5:139537190 NA 0.29 5.41 0.44 3.07e-7 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg23708337 chr7:1209742 NA 0.55 5.47 0.44 2.34e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg23719950 chr11:63933701 MACROD1 -0.72 -5.98 -0.47 2.24e-8 Mean platelet volume; TGCT cis rs6912958 0.678 rs9450733 chr6:88250081 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg09737314 chr17:6899359 ALOX12 0.49 5.23 0.42 7.07e-7 Tonsillectomy; TGCT cis rs7666738 0.753 rs11932536 chr4:98930105 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 1.000 rs7573118 chr2:26308086 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs681343 1.000 rs492602 chr19:49206417 A/G cg13540341 chr19:49222985 MAMSTR -0.33 -4.48 -0.37 1.69e-5 Lung adenocarcinoma;Primary sclerosing cholangitis;Childhood ear infection; TGCT cis rs7192750 0.586 rs2335710 chr16:71923181 C/G cg06353428 chr16:71660113 MARVELD3 -0.83 -7.22 -0.54 4.68e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 -0.97 -8.16 -0.59 3.11e-13 Platelet count; TGCT cis rs1552244 0.882 rs13066757 chr3:10045030 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs12549902 0.932 rs6981607 chr8:41508168 A/C cg21772509 chr8:41503840 NKX6-3 0.89 10.58 0.69 4.81e-19 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs7264396 0.709 rs2425073 chr20:34293699 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.96e-7 Total cholesterol levels; TGCT cis rs4372836 1.000 rs6707848 chr2:28988083 T/C cg09522027 chr2:28974177 PPP1CB -0.62 -5.48 -0.44 2.24e-7 Body mass index; TGCT cis rs62380364 0.602 rs588282 chr5:88032651 G/T cg22951263 chr5:87985283 NA -0.55 -5.94 -0.47 2.74e-8 Intelligence (multi-trait analysis); TGCT cis rs9467773 1.000 rs9986382 chr6:26550619 T/C cg26531700 chr6:26746687 NA 0.48 4.69 0.39 7.1e-6 Intelligence (multi-trait analysis); TGCT cis rs13064447 0.753 rs9811396 chr3:12747915 A/G cg20675869 chr3:12750130 NA 0.19 4.57 0.38 1.18e-5 Major depression and alcohol dependence; TGCT cis rs7647973 1.000 rs13096474 chr3:49443081 C/T cg07636037 chr3:49044803 WDR6 -0.6 -4.78 -0.39 4.83e-6 Menarche (age at onset); TGCT cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg06212747 chr3:49208901 KLHDC8B 0.66 6.18 0.49 8.29e-9 Menarche (age at onset); TGCT cis rs6912958 0.712 rs6454640 chr6:88370352 G/T cg06598631 chr6:88300029 RARS2;ORC3L 0.49 4.5 0.37 1.53e-5 Monocyte percentage of white cells; TGCT cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg17554472 chr22:41940697 POLR3H -0.48 -5.15 -0.42 9.89e-7 Vitiligo; TGCT cis rs782590 0.805 rs782578 chr2:55915904 A/C cg18811423 chr2:55921094 PNPT1 0.71 7.98 0.58 8.2e-13 Metabolic syndrome; TGCT cis rs2832191 0.692 rs2254872 chr21:30414724 C/T cg24692254 chr21:30365293 RNF160 0.99 11.43 0.72 4.08e-21 Dental caries; TGCT cis rs9399135 0.844 rs13209789 chr6:135367916 A/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs2692947 0.832 rs2692954 chr2:96683378 T/G cg13655245 chr2:97463316 CNNM4 0.16 4.54 0.38 1.29e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs610932 0.517 rs584469 chr11:59988862 T/C cg18570331 chr11:60101691 MS4A6E 0.5 4.55 0.38 1.28e-5 Alzheimer's disease; TGCT trans rs1814175 0.817 rs7927373 chr11:49957640 A/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs9952991 0.941 rs60735058 chr18:12795470 T/A cg23544223 chr18:12777786 NA -0.6 -5.36 -0.43 3.89e-7 Inflammatory skin disease; TGCT cis rs797680 0.856 rs4847235 chr1:93627727 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.0 -0.41 1.88e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2458413 0.669 rs1812214 chr8:105344070 A/G cg13045555 chr8:105342365 NA -0.4 -6.63 -0.51 9.03e-10 Paget's disease; TGCT cis rs13242816 1.000 rs17138750 chr7:116134170 A/G cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs67385638 0.855 rs3759074 chr11:5257778 C/T cg12559170 chr11:5275217 HBG2 0.47 8.72 0.62 1.48e-14 Hemoglobin levels; TGCT cis rs60843830 0.662 rs6721594 chr2:305203 C/T cg25945732 chr2:264204 ACP1;SH3YL1 -0.59 -5.91 -0.47 3.12e-8 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9914988 0.943 rs9890377 chr17:27111111 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs17401966 0.931 rs1555849 chr1:10400602 G/T cg19773385 chr1:10388646 KIF1B 0.23 5.43 0.44 2.8e-7 Hepatocellular carcinoma; TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs2404618 0.509 rs13271550 chr8:1488891 C/G cg13402656 chr8:1511478 DLGAP2 -0.36 -6.38 -0.5 3.13e-9 Lung cancer; TGCT cis rs12497850 0.805 rs11130176 chr3:48844077 A/G cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs9296661 0.522 rs1326568 chr6:51665345 G/A cg20180370 chr6:50691003 TFAP2D -0.48 -4.67 -0.39 7.68e-6 Weight loss (gastric bypass surgery); TGCT cis rs4654899 0.758 rs7556221 chr1:21455559 C/G cg01072550 chr1:21505969 NA -0.55 -9.05 -0.63 2.44e-15 Superior frontal gyrus grey matter volume; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs6543140 0.890 rs61122764 chr2:102999520 A/G cg09003973 chr2:102972529 NA 0.56 4.64 0.38 8.7e-6 Blood protein levels; TGCT cis rs6089829 0.962 rs6062393 chr20:61663230 G/A cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs9883204 0.951 rs7614016 chr3:123070426 G/A cg04890266 chr3:123102914 ADCY5 0.37 5.0 0.41 1.92e-6 Birth weight; TGCT cis rs826838 0.967 rs7136593 chr12:39128265 C/T cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs797680 0.897 rs6658257 chr1:93820684 A/G cg17826107 chr1:92977322 EVI5 -0.24 -5.74 -0.46 6.97e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs854765 0.575 rs7207821 chr17:17891781 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.13 0.59 3.81e-13 Total body bone mineral density; TGCT cis rs9467603 0.548 rs34991172 chr6:25480328 T/G cg16898833 chr6:26189333 HIST1H4D 1.33 5.64 0.45 1.07e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg17971929 chr21:40555470 PSMG1 0.96 8.86 0.62 6.96e-15 Cognitive function; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg18538332 chr22:24372958 LOC391322 0.76 6.33 0.49 4e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT trans rs1814175 0.645 rs1851844 chr11:50021773 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs1387259 0.698 rs4579969 chr12:48779562 C/T cg04545296 chr12:48745243 ZNF641 -0.33 -4.62 -0.38 9.3e-6 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs2836950 0.501 rs2070865 chr21:40715519 C/T cg06238570 chr21:40685208 BRWD1 -0.6 -6.07 -0.48 1.45e-8 Menarche (age at onset); TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg26354017 chr1:205819088 PM20D1 0.56 6.81 0.52 3.75e-10 Menarche (age at onset); TGCT cis rs1372520 0.627 rs2583964 chr4:90727218 A/G cg01966878 chr4:90757139 SNCA -0.31 -4.84 -0.4 3.8e-6 Neuroticism; TGCT trans rs1005277 0.579 rs2474594 chr10:38426661 G/C cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs231513 0.911 rs537165 chr17:41976736 C/T cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs6978712 1.000 rs55748686 chr7:127148595 T/C cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs75686122 0.764 rs80100464 chr8:104646434 C/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs2072499 0.966 rs2244144 chr1:156184598 G/A cg25208724 chr1:156163844 SLC25A44 1.11 12.73 0.75 2.98e-24 Testicular germ cell tumor; TGCT cis rs7523273 0.548 rs3109808 chr1:207948477 C/A cg22525895 chr1:207977042 MIR29B2 0.55 9.45 0.65 2.72e-16 Schizophrenia; TGCT cis rs2688608 0.592 rs7908825 chr10:75554541 C/G cg15838173 chr10:75533400 FUT11 0.3 4.89 0.4 3.12e-6 Inflammatory bowel disease; TGCT cis rs10927875 0.541 rs1763596 chr1:16343835 C/T cg21385522 chr1:16154831 NA 0.46 4.79 0.4 4.62e-6 Dilated cardiomyopathy; TGCT cis rs10751667 0.666 rs7394992 chr11:980690 G/C cg06064525 chr11:970664 AP2A2 -0.36 -8.02 -0.58 6.65e-13 Alzheimer's disease (late onset); TGCT cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg16423285 chr20:60520624 NA -0.69 -7.11 -0.54 7.98e-11 Body mass index; TGCT cis rs13326165 0.760 rs13076890 chr3:52407933 T/C cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs595982 0.702 rs626974 chr19:49375900 T/C cg15549821 chr19:49342101 PLEKHA4 -0.37 -5.07 -0.41 1.4e-6 Red cell distribution width; TGCT cis rs12142240 0.698 rs68012736 chr1:46839510 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7267979 0.932 rs6115215 chr20:25562500 C/T cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2456568 0.802 rs7115629 chr11:93635477 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.07e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs14978 0.605 rs4721064 chr7:12284378 G/A cg07541786 chr7:12610355 SCIN 0.47 4.79 0.39 4.75e-6 Response to amphetamines; TGCT cis rs7412746 0.658 rs2230061 chr1:150727539 G/A cg09365446 chr1:150670422 GOLPH3L 0.33 4.78 0.39 4.8e-6 Melanoma; TGCT cis rs7267979 1.000 rs2257982 chr20:25269630 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs916888 0.821 rs199514 chr17:44856881 G/A cg17911788 chr17:44343683 NA 0.61 6.44 0.5 2.42e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2153535 0.606 rs11243253 chr6:8380193 T/C cg23788917 chr6:8435910 SLC35B3 -0.65 -5.93 -0.47 2.87e-8 Motion sickness; TGCT trans rs9929218 0.551 rs1886697 chr16:68716179 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.63 8.21 0.59 2.47e-13 Colorectal cancer; TGCT cis rs7714584 1.000 rs7709464 chr5:150269441 C/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs11754661 1.000 rs11754661 chr6:151207078 G/A cg01354656 chr6:151411710 MTHFD1L 0.45 4.53 0.38 1.37e-5 Alzheimer's disease (late onset); TGCT cis rs2070488 0.932 rs1841776 chr3:38480727 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg20887711 chr4:1340912 KIAA1530 -0.68 -6.0 -0.47 1.99e-8 Obesity-related traits; TGCT cis rs2204008 0.807 rs4123933 chr12:37973539 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs9341808 0.718 rs6910201 chr6:80904938 G/C cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT trans rs3780486 0.718 rs3818593 chr9:33120706 A/G cg04842962 chr6:43655489 MRPS18A 0.98 7.28 0.55 3.36e-11 IgG glycosylation; TGCT cis rs67311347 1.000 rs9834052 chr3:40399060 G/A cg17264618 chr3:40429014 ENTPD3 0.31 4.65 0.39 8.38e-6 Renal cell carcinoma; TGCT cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg12310025 chr6:25882481 NA 0.49 5.0 0.41 1.92e-6 Blood metabolite levels; TGCT cis rs769267 0.930 rs2315022 chr19:19413381 A/G cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs939658 0.805 rs34222382 chr15:79440748 C/T cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs9902453 0.934 rs34433787 chr17:28496780 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs2153535 0.563 rs4428546 chr6:8490376 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg26531700 chr6:26746687 NA 0.67 6.47 0.5 2.09e-9 Intelligence (multi-trait analysis); TGCT cis rs2486288 0.656 rs12911861 chr15:45566718 T/C cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.07 -0.41 1.41e-6 Glomerular filtration rate; TGCT cis rs7584330 0.554 rs6736468 chr2:238422228 A/G cg08992911 chr2:238395768 MLPH 0.69 4.77 0.39 5e-6 Prostate cancer; TGCT trans rs7819412 0.775 rs6601564 chr8:10982051 A/G cg15556689 chr8:8085844 FLJ10661 -0.82 -8.06 -0.59 5.57e-13 Triglycerides; TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs56104184 0.830 rs45589039 chr19:49355385 C/T cg21252483 chr19:49399788 TULP2 -0.41 -5.21 -0.42 7.47e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs709400 0.628 rs7150317 chr14:103921691 C/G cg12935359 chr14:103987150 CKB -0.35 -5.33 -0.43 4.54e-7 Body mass index; TGCT cis rs7829975 0.540 rs2976909 chr8:8346690 C/T cg08975724 chr8:8085496 FLJ10661 -0.52 -5.35 -0.43 4.06e-7 Mood instability; TGCT cis rs9549260 0.592 rs9315783 chr13:41289164 T/C cg21288729 chr13:41239152 FOXO1 0.87 7.86 0.58 1.59e-12 Red blood cell count; TGCT cis rs7246657 0.722 rs10406379 chr19:38036725 G/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs6089584 0.508 rs6061988 chr20:60626300 C/T cg13770153 chr20:60521292 NA -0.42 -4.95 -0.41 2.37e-6 Body mass index; TGCT cis rs473651 0.904 rs501333 chr2:239336045 G/A cg18131467 chr2:239335373 ASB1 1.02 15.09 0.8 7.51e-30 Multiple system atrophy; TGCT cis rs2236918 0.687 rs2797601 chr1:242029249 C/G cg04158730 chr1:242011433 EXO1 0.56 5.2 0.42 8.05e-7 Menopause (age at onset); TGCT cis rs6121246 0.567 rs6058203 chr20:30198979 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs9325144 0.577 rs10876008 chr12:39126750 T/C cg26384229 chr12:38710491 ALG10B -0.61 -5.7 -0.46 8.45e-8 Morning vs. evening chronotype; TGCT cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 6.09 0.48 1.32e-8 Attention deficit hyperactivity disorder; TGCT cis rs1045714 0.895 rs4721866 chr7:2643341 G/A cg17215154 chr7:2644645 IQCE 0.28 4.92 0.4 2.75e-6 Urate levels in lean individuals; TGCT cis rs7666738 0.645 rs10013290 chr4:99082799 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.01 0.41 1.83e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs10506458 0.915 rs79133015 chr12:63396838 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs4975709 0.569 rs2353583 chr5:1858834 G/C cg07747251 chr5:1868357 NA 0.38 5.31 0.43 4.95e-7 Cardiovascular disease risk factors; TGCT cis rs7208859 0.614 rs4794874 chr17:28841318 C/T cg13385521 chr17:29058706 SUZ12P -0.69 -4.57 -0.38 1.18e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1801251 0.963 rs35395584 chr2:233573698 G/C cg08000102 chr2:233561755 GIGYF2 0.66 6.84 0.52 3.29e-10 Coronary artery disease; TGCT cis rs17108533 0.588 rs12897337 chr14:71302994 A/G cg23900759 chr14:71108106 TTC9 -1.15 -4.79 -0.39 4.73e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs7523273 0.927 rs1891423 chr1:207931913 G/A cg22525895 chr1:207977042 MIR29B2 0.47 8.1 0.59 4.31e-13 Schizophrenia; TGCT cis rs858239 0.539 rs2103281 chr7:23194231 A/G cg05602783 chr7:23145260 KLHL7 -0.67 -5.47 -0.44 2.37e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.56 4.81 0.4 4.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4523957 0.583 rs923863 chr17:2031387 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9814567 0.806 rs9824185 chr3:134324024 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.77 -7.21 -0.54 4.87e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11785400 1.000 rs3802232 chr8:143746701 A/G cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs514406 0.505 rs12726160 chr1:53175099 A/G cg01802117 chr1:53393560 SCP2 -0.44 -5.18 -0.42 8.57e-7 Monocyte count; TGCT cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg06634786 chr22:41940651 POLR3H -0.89 -8.69 -0.62 1.79e-14 Vitiligo; TGCT cis rs7829975 0.658 rs907181 chr8:8702875 T/C cg15556689 chr8:8085844 FLJ10661 0.67 6.28 0.49 5.11e-9 Mood instability; TGCT cis rs2963155 0.518 rs712189 chr5:142631258 C/T cg17617527 chr5:142782415 NR3C1 0.85 6.29 0.49 4.9e-9 Breast cancer; TGCT cis rs727563 0.593 rs5758461 chr22:42162189 G/C cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Crohn's disease;Inflammatory bowel disease; TGCT cis rs453301 0.686 rs6748 chr8:8890802 C/T cg15556689 chr8:8085844 FLJ10661 -0.62 -5.24 -0.43 6.69e-7 Joint mobility (Beighton score); TGCT cis rs9733 0.596 rs1415148 chr1:150705755 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs7221109 0.522 rs2462970 chr17:38871049 A/G cg07480653 chr17:39868082 GAST -0.24 -5.14 -0.42 1.04e-6 Type 1 diabetes; TGCT cis rs6912958 0.500 rs2025486 chr6:87796886 T/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.54 -0.38 1.33e-5 Monocyte percentage of white cells; TGCT cis rs916888 0.821 rs199509 chr17:44858728 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs76944716 chr8:58191643 T/C cg08280861 chr8:58055591 NA 0.36 4.82 0.4 4.2e-6 Developmental language disorder (linguistic errors); TGCT cis rs9807989 0.507 rs2293224 chr2:103035779 T/C cg03938978 chr2:103052716 IL18RAP 0.27 5.4 0.44 3.31e-7 Asthma; TGCT cis rs4523957 0.620 rs898749 chr17:2085185 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2299587 0.607 rs2237848 chr8:17874604 A/C cg04898035 chr8:17640624 MTUS1 -0.21 -4.56 -0.38 1.19e-5 Economic and political preferences; TGCT cis rs2839186 0.934 rs4819221 chr21:47695417 G/T cg13732083 chr21:47605072 C21orf56 -0.34 -4.59 -0.38 1.07e-5 Testicular germ cell tumor; TGCT cis rs7085104 0.700 rs10883785 chr10:104603588 A/G cg04362960 chr10:104952993 NT5C2 0.57 5.05 0.41 1.54e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs9814567 0.806 rs11927540 chr3:134319455 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg20607798 chr8:58055168 NA 0.66 5.87 0.47 3.66e-8 Developmental language disorder (linguistic errors); TGCT cis rs2562456 0.682 rs11085464 chr19:21751778 C/G cg01304269 chr19:21688519 ZNF429 0.58 4.74 0.39 5.78e-6 Pain; TGCT cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg11890956 chr21:40555474 PSMG1 1.1 12.28 0.74 3.66e-23 Cognitive function; TGCT cis rs5750830 0.594 rs5757648 chr22:39775156 G/A cg11247378 chr22:39784982 NA -0.64 -8.48 -0.61 5.71e-14 Intelligence (multi-trait analysis); TGCT cis rs2243480 0.706 rs34466769 chr7:65453292 A/C cg07424592 chr7:64974309 NA 0.96 6.03 0.48 1.78e-8 Diabetic kidney disease; TGCT cis rs6500602 0.929 rs9926114 chr16:4478322 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.16 0.42 9.6e-7 Schizophrenia; TGCT cis rs9527 0.590 rs12775302 chr10:104911356 A/G cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.09e-7 Arsenic metabolism; TGCT cis rs3020333 0.721 rs1293936 chr6:152017691 T/G cg22157087 chr6:152012887 ESR1 0.23 5.59 0.45 1.36e-7 Total body bone mineral density; TGCT cis rs904251 0.522 rs882322 chr6:37484103 A/G cg01843034 chr6:37503916 NA -0.54 -7.33 -0.55 2.57e-11 Cognitive performance; TGCT cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg18252515 chr7:66147081 NA -1.22 -7.98 -0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs1008375 0.966 rs6833808 chr4:17652526 T/A cg16339924 chr4:17578868 LAP3 0.68 5.61 0.45 1.26e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6964587 1.000 rs36120033 chr7:91679298 G/A cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs1577917 0.545 rs1832070 chr6:86483172 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.6 4.94 0.41 2.47e-6 Response to antipsychotic treatment; TGCT cis rs611744 0.647 rs1379336 chr8:109276606 G/T cg21045802 chr8:109455806 TTC35 0.72 7.39 0.55 1.92e-11 Dupuytren's disease; TGCT cis rs4478858 0.602 rs6425723 chr1:31715204 T/C cg00250761 chr1:31883323 NA -0.27 -4.89 -0.4 3.11e-6 Alcohol dependence; TGCT cis rs617219 0.698 rs13177470 chr5:78495899 T/C cg23514016 chr5:78407564 BHMT 0.35 5.44 0.44 2.78e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9325144 0.560 rs2387923 chr12:38662677 G/A cg26384229 chr12:38710491 ALG10B -0.63 -5.92 -0.47 2.9e-8 Morning vs. evening chronotype; TGCT cis rs6964587 0.773 rs12740 chr7:92029302 A/G cg17063962 chr7:91808500 NA 0.84 7.84 0.58 1.75e-12 Breast cancer; TGCT cis rs12893668 0.703 rs4906335 chr14:104021141 C/A cg26031613 chr14:104095156 KLC1 -0.54 -4.55 -0.38 1.28e-5 Reticulocyte count; TGCT cis rs1997103 0.954 rs6593236 chr7:55410992 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs651907 0.535 rs11714444 chr3:101513682 G/A cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg01802117 chr1:53393560 SCP2 0.48 5.82 0.46 4.82e-8 Monocyte count; TGCT cis rs6586111 1.000 rs4934372 chr10:82372981 A/G cg03086067 chr10:82368399 SH2D4B 0.24 4.7 0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs9300255 0.639 rs941306 chr12:123715113 C/T cg00376283 chr12:123451042 ABCB9 0.67 5.26 0.43 6.13e-7 Neutrophil percentage of white cells; TGCT cis rs597539 0.652 rs507520 chr11:68666054 C/T cg04772025 chr11:68637568 NA 0.6 6.79 0.52 4.07e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs903263 0.932 rs1565823 chr1:84576620 G/A cg09664975 chr1:84543551 PRKACB 0.49 4.55 0.38 1.24e-5 Breast cancer (male); TGCT cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg13395646 chr4:1353034 KIAA1530 -0.48 -6.1 -0.48 1.28e-8 Obesity-related traits; TGCT cis rs73198271 0.595 rs55874147 chr8:8591954 T/C ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs17102423 0.594 rs1124752 chr14:65567515 G/T cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.57e-9 Obesity-related traits; TGCT trans rs9388451 1.000 rs9388451 chr6:126090377 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.77 -8.56 -0.61 3.6e-14 Brugada syndrome; TGCT cis rs6866344 0.561 rs55974982 chr5:178141421 G/A cg03877680 chr5:178157825 ZNF354A 0.77 6.78 0.52 4.28e-10 Neutrophil percentage of white cells; TGCT cis rs2404602 0.647 rs11072612 chr15:76960984 A/T cg22467129 chr15:76604101 ETFA 0.47 4.65 0.39 8.48e-6 Blood metabolite levels; TGCT cis rs9902453 0.704 rs1972305 chr17:28533880 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.64 5.96 0.47 2.43e-8 Coffee consumption (cups per day); TGCT cis rs2072499 0.778 rs2247476 chr1:156190280 C/A cg24450063 chr1:156163899 SLC25A44 1.03 9.7 0.66 6.62e-17 Testicular germ cell tumor; TGCT cis rs8033133 0.602 rs1549477 chr15:25332118 C/T cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.24 -4.58 -0.38 1.1e-5 Blood osmolality (transformed sodium); TGCT cis rs10782582 0.617 rs1846233 chr1:76159354 C/T cg22875332 chr1:76189707 ACADM -0.55 -6.35 -0.5 3.77e-9 Daytime sleep phenotypes; TGCT cis rs7267979 1.000 rs6083828 chr20:25369918 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1005277 0.540 rs289638 chr10:37923731 G/A cg17830980 chr10:43048298 ZNF37B -0.67 -7.5 -0.56 1.05e-11 Extrinsic epigenetic age acceleration; TGCT cis rs2046867 0.866 rs2244246 chr3:72789191 G/A cg25664220 chr3:72788482 NA 0.55 6.96 0.53 1.75e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs763121 0.752 rs6001190 chr22:39073811 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.43 0.56 1.54e-11 Menopause (age at onset); TGCT cis rs12549902 0.966 rs716199 chr8:41515531 A/G cg00088007 chr8:41504566 NKX6-3 0.34 5.31 0.43 4.93e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT trans rs1496653 0.602 rs71322184 chr3:23439190 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs2836633 0.895 rs61085980 chr21:40032140 C/T cg05519781 chr21:40033154 ERG 0.66 6.38 0.5 3.15e-9 Coronary artery disease; TGCT cis rs2811893 1.000 rs232775 chr1:59124546 A/G cg26196860 chr1:59745563 NA 0.25 4.68 0.39 7.49e-6 Diabetic retinopathy; TGCT cis rs4794202 0.534 rs9895764 chr17:45927961 C/G cg02219949 chr17:45927392 SP6 0.38 4.55 0.38 1.24e-5 Alzheimer's disease (cognitive decline); TGCT cis rs9859260 0.744 rs419059 chr3:195782184 C/T cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs473651 0.904 rs62196716 chr2:239356977 C/G cg21699342 chr2:239360505 ASB1 0.17 4.74 0.39 5.66e-6 Multiple system atrophy; TGCT cis rs1538970 0.816 rs11211124 chr1:45962409 T/C cg05343316 chr1:45956843 TESK2 0.81 6.64 0.51 8.93e-10 Platelet count; TGCT cis rs727563 0.594 rs5758408 chr22:42077737 A/C cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs13242816 1.000 rs35800921 chr7:116124041 G/A cg02799643 chr7:116139180 CAV2 -0.49 -5.53 -0.45 1.78e-7 P wave duration; TGCT cis rs116095464 0.558 rs62347683 chr5:230331 C/T cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs77741769 0.529 rs7137504 chr12:121221628 C/T cg02419362 chr12:121203948 SPPL3 0.19 4.47 0.37 1.74e-5 Mean corpuscular volume; TGCT cis rs1055129 0.560 rs2305913 chr17:73922941 T/C cg08125733 chr17:73851984 WBP2 0.57 5.22 0.42 7.14e-7 White matter hyperintensity burden; TGCT cis rs826838 0.967 rs11183514 chr12:38760744 A/T cg13010199 chr12:38710504 ALG10B 0.82 6.86 0.52 2.91e-10 Heart rate; TGCT cis rs7809950 0.724 rs1858888 chr7:107046062 T/A cg23024343 chr7:107201750 COG5 -0.48 -6.3 -0.49 4.82e-9 Coronary artery disease; TGCT cis rs6141769 0.542 rs6058821 chr20:31304713 C/T cg13636640 chr20:31349939 DNMT3B -0.51 -4.48 -0.37 1.68e-5 Subjective well-being; TGCT cis rs10791097 0.694 rs10894275 chr11:130756251 C/T cg14779329 chr11:130786720 SNX19 0.29 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.5 4.69 0.39 7.06e-6 Colorectal cancer; TGCT cis rs8177253 1.000 rs8177272 chr3:133482870 C/T cg16414030 chr3:133502952 NA -0.61 -9.53 -0.65 1.78e-16 Iron status biomarkers; TGCT cis rs7731657 0.537 rs4637539 chr5:130311944 T/C cg08523029 chr5:130500466 HINT1 -0.57 -4.54 -0.38 1.33e-5 Fasting plasma glucose; TGCT cis rs28785552 0.765 rs28850924 chr19:53234323 T/G cg22067481 chr19:53234126 ZNF611 -0.48 -6.8 -0.52 3.98e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs6121246 0.529 rs750144 chr20:30179027 C/T cg13852791 chr20:30311386 BCL2L1 -0.69 -4.53 -0.38 1.36e-5 Mean corpuscular hemoglobin; TGCT cis rs7552404 0.924 rs7546641 chr1:76158035 T/C cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg08859206 chr1:53392774 SCP2 -0.49 -7.71 -0.57 3.61e-12 Monocyte count; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg07205460 chr22:24236375 MIF 0.59 4.65 0.39 8.26e-6 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs17767294 0.708 rs72848755 chr6:27878553 T/C cg08851530 chr6:28072375 NA 1.53 7.17 0.54 6.02e-11 Parkinson's disease; TGCT cis rs10206020 0.921 rs6605278 chr2:1547230 C/T cg12573674 chr2:1569213 NA -0.49 -4.95 -0.41 2.41e-6 IgG glycosylation; TGCT cis rs7010267 0.570 rs2326193 chr8:120029709 A/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.69 0.39 7.07e-6 Total body bone mineral density (age 45-60); TGCT cis rs6933660 0.683 rs8180642 chr6:151756612 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.49 4.49 0.37 1.58e-5 Menarche (age at onset); TGCT cis rs4631830 0.863 rs4935162 chr10:51525699 C/G cg10326726 chr10:51549505 MSMB -0.25 -4.87 -0.4 3.4e-6 Prostate-specific antigen levels; TGCT cis rs17376456 0.825 rs55947981 chr5:93278104 G/T cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs7208859 0.673 rs28588622 chr17:29245699 G/A cg14008862 chr17:28927542 LRRC37B2 0.71 4.67 0.39 7.67e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg13944838 chr5:179740914 GFPT2 -0.4 -6.27 -0.49 5.56e-9 Height; TGCT cis rs3741151 1.000 rs111882289 chr11:73053714 T/C cg17517138 chr11:73019481 ARHGEF17 1.06 5.6 0.45 1.3e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs8044995 0.563 rs57434514 chr16:68402649 G/A cg05110241 chr16:68378359 PRMT7 -0.36 -4.46 -0.37 1.84e-5 Schizophrenia; TGCT cis rs7428 0.545 rs7572750 chr2:85552186 C/A cg03728395 chr2:85555865 TGOLN2 -0.31 -5.17 -0.42 8.93e-7 Ear protrusion; TGCT cis rs7267979 0.789 rs4815429 chr20:25521611 T/C cg16686733 chr20:25566563 NINL -0.52 -5.05 -0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs875971 0.929 rs778682 chr7:65837934 A/G cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.11e-6 Aortic root size; TGCT cis rs7975161 0.630 rs7138317 chr12:104650271 G/A cg25273343 chr12:104657179 TXNRD1 -0.35 -4.83 -0.4 3.87e-6 Toenail selenium levels; TGCT cis rs10838634 1.000 rs60940896 chr11:46870593 T/C cg18332754 chr11:46939436 LRP4 0.91 4.61 0.38 9.98e-6 Schizophrenia; TGCT cis rs7659604 0.537 rs6823818 chr4:122731699 G/C cg06713675 chr4:122721982 EXOSC9 -0.69 -9.69 -0.66 7.11e-17 Type 2 diabetes; TGCT cis rs6674176 0.628 rs3791116 chr1:44414156 T/A cg13606994 chr1:44402422 ARTN -0.46 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs35306767 0.579 rs7091502 chr10:1154979 C/T cg18964960 chr10:1102726 WDR37 0.65 4.45 0.37 1.93e-5 Eosinophil percentage of granulocytes; TGCT cis rs4689388 0.926 rs10012946 chr4:6293350 C/T cg14416269 chr4:6271139 WFS1 -0.44 -5.39 -0.44 3.46e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs748404 0.560 rs2255663 chr15:43829008 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.46 -4.49 -0.37 1.63e-5 Lung cancer; TGCT cis rs72627509 0.680 rs56162812 chr4:57740667 G/A cg26694713 chr4:57773883 REST 0.82 6.68 0.51 7.07e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.07 15.03 0.8 1.05e-29 Prudent dietary pattern; TGCT cis rs9549367 0.713 rs9549682 chr13:113830181 C/T cg00898013 chr13:113819073 PROZ -0.55 -7.05 -0.53 1.12e-10 Platelet distribution width; TGCT cis rs1525293 0.714 rs12698976 chr7:70501199 C/T cg21135135 chr7:70597687 WBSCR17 -0.54 -4.97 -0.41 2.13e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs9926296 0.546 rs7187436 chr16:89845110 A/T cg27121462 chr16:89883253 FANCA 0.78 8.21 0.59 2.48e-13 Vitiligo; TGCT cis rs9894429 1.000 rs4074916 chr17:79579248 G/A cg21028142 chr17:79581711 NPLOC4 -0.29 -6.7 -0.52 6.64e-10 Eye color traits; TGCT cis rs769267 0.930 rs892021 chr19:19613480 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs7843479 0.601 rs10101881 chr8:21830158 A/G cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.07e-12 Mean corpuscular volume; TGCT cis rs9473924 0.505 rs55653665 chr6:50812984 T/C cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs17331151 0.505 rs71299613 chr3:52698805 G/A cg15956490 chr3:53032818 SFMBT1 0.7 5.71 0.46 7.8e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1691799 0.899 rs1168293 chr12:66733904 G/A cg16791601 chr12:66731901 HELB -0.28 -5.95 -0.47 2.5e-8 White blood cell count (basophil); TGCT cis rs6933660 0.800 rs6930557 chr6:151755806 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.7 7.16 0.54 6.38e-11 Menarche (age at onset); TGCT cis rs9318086 0.753 rs9553094 chr13:24474613 A/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.7 -7.21 -0.54 4.85e-11 Myopia (pathological); TGCT cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs1153858 1.000 rs7169818 chr15:45640191 G/A cg26924012 chr15:45694286 SPATA5L1 0.97 11.83 0.73 4.55e-22 Homoarginine levels; TGCT cis rs4253772 0.513 rs11090863 chr22:46705407 C/T cg24881330 chr22:46731750 TRMU 1.05 5.46 0.44 2.5e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs1005277 0.579 rs2505241 chr10:38442421 T/C cg25427524 chr10:38739819 LOC399744 -0.4 -8.24 -0.59 2.07e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2242194 0.816 rs6671688 chr1:154994265 T/C cg16680214 chr1:154839983 KCNN3 -0.31 -5.76 -0.46 6.3e-8 Schizophrenia; TGCT cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Vitiligo; TGCT cis rs4478858 0.746 rs6703593 chr1:31689284 A/C cg00250761 chr1:31883323 NA 0.29 4.78 0.39 4.9e-6 Alcohol dependence; TGCT cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs2456568 0.867 rs72962810 chr11:93663619 A/G cg26875233 chr11:93583750 C11orf90 -0.46 -5.76 -0.46 6.28e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6456156 0.792 rs4710181 chr6:167513998 T/C cg07741184 chr6:167504864 NA 0.22 4.51 0.38 1.48e-5 Primary biliary cholangitis; TGCT cis rs1538970 0.962 rs2298018 chr1:45813441 T/C cg05343316 chr1:45956843 TESK2 0.64 5.13 0.42 1.08e-6 Platelet count; TGCT cis rs10088262 0.527 rs3911939 chr8:124793744 T/G cg02993010 chr8:124780839 FAM91A1 -0.64 -4.58 -0.38 1.1e-5 Pancreatic cancer; TGCT cis rs1797081 0.967 rs811912 chr10:16859618 G/C cg14835575 chr10:16859367 RSU1 0.41 4.85 0.4 3.61e-6 Platelet distribution width; TGCT cis rs1670533 0.872 rs13108222 chr4:1054256 C/A cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs7208859 0.623 rs8079891 chr17:29058863 G/A cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs752010 0.715 rs11807117 chr1:42101206 C/T cg06885757 chr1:42089581 HIVEP3 0.28 4.91 0.4 2.79e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs9393777 0.513 rs9368448 chr6:26649355 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs473651 0.935 rs540636 chr2:239358341 T/C cg18131467 chr2:239335373 ASB1 1.01 14.8 0.8 3.56e-29 Multiple system atrophy; TGCT cis rs6589563 0.737 rs11825181 chr11:116626258 G/A cg20660624 chr11:117307972 DSCAML1 -0.38 -4.99 -0.41 2.02e-6 Eosinophil counts; TGCT cis rs28595532 0.920 rs114966881 chr4:119761078 C/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg23131131 chr22:24373011 LOC391322 0.7 7.28 0.55 3.34e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6866344 0.697 rs17184281 chr5:178127563 G/A cg10224037 chr5:178157518 ZNF354A 0.93 7.9 0.58 1.26e-12 Neutrophil percentage of white cells; TGCT cis rs3008870 1.000 rs2985794 chr1:67425311 T/G cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs7659604 0.846 rs60340409 chr4:122666355 G/C cg19748678 chr4:122722346 EXOSC9 0.55 5.31 0.43 4.92e-7 Type 2 diabetes; TGCT cis rs8070740 0.731 rs1071648 chr17:5326089 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs4595586 0.545 rs12816776 chr12:39375817 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2862064 1.000 rs11747316 chr5:156422948 A/G cg12943317 chr5:156479607 HAVCR1 -0.43 -5.67 -0.45 9.29e-8 Platelet count; TGCT trans rs9383153 0.793 rs2016498 chr6:16344914 C/T cg19895197 chr17:37887061 C17orf37 -0.96 -7.23 -0.54 4.28e-11 Gambling; TGCT cis rs709400 0.628 rs7146506 chr14:103924477 A/G cg26031613 chr14:104095156 KLC1 0.85 9.49 0.65 2.17e-16 Body mass index; TGCT cis rs9859260 0.710 rs41298097 chr3:195779155 C/T cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs4765905 0.500 rs2239030 chr12:2335941 A/G cg07807026 chr12:2041581 NA 0.25 4.59 0.38 1.06e-5 Schizophrenia; TGCT cis rs9296092 0.538 rs9469487 chr6:33516943 G/T cg13560919 chr6:33536144 NA -0.21 -4.74 -0.39 5.87e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs651907 0.514 rs10936744 chr3:101433440 C/T cg12386194 chr3:101231763 SENP7 0.51 4.9 0.4 2.89e-6 Colorectal cancer; TGCT cis rs6912958 0.781 rs3918467 chr6:88180388 C/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.54 -5.23 -0.43 7.03e-7 Monocyte percentage of white cells; TGCT cis rs2430386 1.000 rs2430386 chr2:63178111 C/T cg17519650 chr2:63277830 OTX1 0.7 6.93 0.53 2.01e-10 Prostate cancer; TGCT cis rs1969363 0.531 rs11495331 chr12:38110702 A/G cg26384229 chr12:38710491 ALG10B 0.59 5.12 0.42 1.16e-6 Morning vs. evening chronotype; TGCT cis rs875971 0.929 rs778712 chr7:65849978 C/T cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs6125597 0.967 rs6067025 chr20:47854020 T/C cg11220565 chr20:47934802 NA -0.3 -4.6 -0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs4722166 0.541 rs1800795 chr7:22766645 C/G cg26061582 chr7:22766209 IL6 0.47 6.32 0.49 4.29e-9 Lung cancer; TGCT cis rs2072499 0.966 rs1060604 chr1:156184268 T/C cg06970220 chr1:156163860 SLC25A44 0.74 5.91 0.47 3.05e-8 Testicular germ cell tumor; TGCT cis rs9837602 0.529 rs793458 chr3:99520169 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.71 0.52 6.1e-10 Breast cancer; TGCT cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs644799 0.687 rs11021318 chr11:95522996 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.65 0.61 2.18e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4665809 1.000 rs6729757 chr2:26285102 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs2718812 0.766 rs2589269 chr3:133409977 C/T cg16414030 chr3:133502952 NA 0.41 5.55 0.45 1.64e-7 Iron status biomarkers; TGCT cis rs10883723 0.810 rs10786671 chr10:104271303 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7666738 0.791 rs13146909 chr4:98934198 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.57 -5.6 -0.45 1.31e-7 Intelligence (multi-trait analysis); TGCT cis rs9611519 0.580 rs8138349 chr22:41412723 C/T cg13695892 chr22:41940480 POLR3H -0.54 -5.1 -0.42 1.21e-6 Neuroticism; TGCT cis rs7097610 1 rs7097610 chr10:82304162 C/T cg01528321 chr10:82214614 TSPAN14 -0.85 -5.28 -0.43 5.6e-7 Post bronchodilator FEV1; TGCT cis rs72945132 0.882 rs55905028 chr11:70127750 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9926296 0.632 rs72807526 chr16:89775946 A/G cg04287289 chr16:89883240 FANCA -0.57 -5.05 -0.41 1.55e-6 Vitiligo; TGCT cis rs7681440 0.647 rs6824979 chr4:90819407 C/G cg10208370 chr4:90758469 SNCA 0.57 5.37 0.43 3.69e-7 Dementia with Lewy bodies; TGCT cis rs1395 1.000 rs1275528 chr2:27430781 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.49 -6.62 -0.51 9.77e-10 Blood metabolite levels; TGCT cis rs3125734 0.633 rs10821968 chr10:63993905 C/T cg09941381 chr10:64027924 RTKN2 0.34 5.31 0.43 4.98e-7 Rheumatoid arthritis; TGCT cis rs6061231 0.583 rs2427313 chr20:60970675 G/A cg24112000 chr20:60950667 NA -0.37 -4.89 -0.4 3.06e-6 Colorectal cancer; TGCT cis rs910316 0.967 rs4899551 chr14:75660246 C/G cg11812906 chr14:75593930 NEK9 -0.72 -6.93 -0.53 2.01e-10 Height; TGCT cis rs4713118 0.506 rs9366697 chr6:27633018 T/C cg10876282 chr6:28092338 ZSCAN16 0.49 4.89 0.4 3.08e-6 Parkinson's disease; TGCT cis rs6076065 0.548 rs6048742 chr20:23327584 T/C cg11657817 chr20:23433608 CST11 0.28 4.92 0.4 2.68e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs36051895 0.632 rs10974993 chr9:5182159 C/T cg02405213 chr9:5042618 JAK2 -0.76 -10.76 -0.69 1.8e-19 Pediatric autoimmune diseases; TGCT cis rs7940866 0.801 rs2113929 chr11:130835974 G/A cg05962950 chr11:130786565 SNX19 0.74 7.18 0.54 5.63e-11 Schizophrenia; TGCT cis rs56309584 0.715 rs3027234 chr17:8136092 C/T cg08322244 chr17:8066669 VAMP2 -0.57 -5.19 -0.42 8.26e-7 Initial pursuit acceleration; TGCT cis rs2832191 0.791 rs2832202 chr21:30501342 G/A cg24692254 chr21:30365293 RNF160 -0.89 -9.49 -0.65 2.2e-16 Dental caries; TGCT cis rs651907 0.535 rs34648996 chr3:101511202 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs739496 0.579 rs11066077 chr12:112346661 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7617773 0.780 rs13066044 chr3:48377276 C/T cg11946769 chr3:48343235 NME6 0.82 6.99 0.53 1.49e-10 Coronary artery disease; TGCT cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs16867321 0.671 rs6712709 chr2:181492933 G/A cg23363182 chr2:181467187 NA -0.45 -4.79 -0.4 4.59e-6 Obesity; TGCT cis rs7104764 0.917 rs6598068 chr11:243092 A/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs13168506 0.538 rs12521857 chr5:135440364 G/A cg00308130 chr5:135415190 NA -0.32 -4.52 -0.38 1.44e-5 Stroke; TGCT cis rs9467773 0.572 rs2076029 chr6:26390830 T/C cg05738196 chr6:26577821 NA -0.5 -5.19 -0.42 8.47e-7 Intelligence (multi-trait analysis); TGCT cis rs1797081 0.967 rs780633 chr10:16863161 C/T cg23933602 chr10:16859644 RSU1 1.04 13.03 0.76 5.47e-25 Platelet distribution width; TGCT cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg17747265 chr1:1875780 NA -0.39 -7.23 -0.54 4.29e-11 Body mass index; TGCT cis rs1008375 0.931 rs3796814 chr4:17602033 G/C cg18681998 chr4:17616180 MED28 0.98 10.43 0.68 1.17e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10782582 0.593 rs2147039 chr1:76143166 C/T cg22875332 chr1:76189707 ACADM -0.56 -6.44 -0.5 2.43e-9 Daytime sleep phenotypes; TGCT cis rs6815814 0.851 rs11466645 chr4:38778203 A/T cg02016764 chr4:38805732 TLR1 -0.35 -5.51 -0.44 1.96e-7 Breast cancer; TGCT cis rs3796352 1.000 rs35576914 chr3:53092270 G/A cg15956490 chr3:53032818 SFMBT1 0.6 6.78 0.52 4.31e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9291683 0.552 rs10939656 chr4:10014646 A/C cg00071950 chr4:10020882 SLC2A9 0.76 10.25 0.68 3.14e-18 Bone mineral density; TGCT cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg03303774 chr4:1407052 NA 0.31 4.87 0.4 3.31e-6 Obesity-related traits; TGCT cis rs67478160 0.595 rs67768834 chr14:104221085 C/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs2758596 1.000 rs2842866 chr1:156159721 G/A cg25208724 chr1:156163844 SLC25A44 0.84 5.09 0.42 1.27e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs1046896 0.553 rs2292965 chr17:80900645 G/A cg03160526 chr17:80928410 B3GNTL1 0.33 4.44 0.37 1.95e-5 Glycated hemoglobin levels; TGCT cis rs4268898 0.722 rs7564420 chr2:24414002 C/T cg05570707 chr2:24270316 C2orf44 -0.47 -4.63 -0.38 9.07e-6 Asthma; TGCT cis rs259282 0.605 rs55687317 chr19:33109191 G/A cg26639809 chr19:33781782 NA 0.25 5.04 0.41 1.6e-6 Schizophrenia; TGCT cis rs4273100 0.688 rs1533034 chr17:19153175 G/C cg01534423 chr17:18965556 NA 0.78 6.78 0.52 4.25e-10 Schizophrenia; TGCT cis rs11690935 1.000 rs35549875 chr2:172532392 A/G cg13550731 chr2:172543902 DYNC1I2 1.2 12.91 0.76 1.08e-24 Schizophrenia; TGCT cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg20637647 chr7:64974828 NA 0.94 5.16 0.42 9.35e-7 Diabetic kidney disease; TGCT cis rs10465746 0.752 rs10874426 chr1:84451820 A/G cg10977910 chr1:84465055 TTLL7 0.63 6.13 0.48 1.07e-8 Obesity-related traits; TGCT cis rs4242434 0.854 rs11782130 chr8:22452357 G/T cg03733263 chr8:22462867 KIAA1967 1.1 17.29 0.84 7.63e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs634534 0.622 rs624273 chr11:65712413 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 5.17 0.42 9.27e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.33 -0.55 2.65e-11 Colorectal cancer; TGCT cis rs6951245 0.608 rs10252234 chr7:1114381 C/T cg09177884 chr7:1199841 ZFAND2A -0.56 -4.66 -0.39 8.14e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11677370 0.603 rs10164826 chr2:3849951 G/C cg17052675 chr2:3827356 NA -0.42 -7.13 -0.54 7.31e-11 Type 2 diabetes; TGCT cis rs6831352 0.959 rs4699710 chr4:100051819 C/T cg12011299 chr4:100065546 ADH4 0.41 5.2 0.42 8.11e-7 Alcohol dependence; TGCT cis rs9311474 1.000 rs7629072 chr3:52305633 C/T cg07507251 chr3:52567010 NT5DC2 0.44 5.99 0.47 2.09e-8 Electroencephalogram traits; TGCT cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg21644426 chr2:191273491 MFSD6 0.62 6.15 0.48 9.57e-9 Pulse pressure; TGCT cis rs3008870 1.000 rs2985795 chr1:67426223 A/G cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs9677476 0.515 rs2303353 chr2:231944373 A/T cg07929768 chr2:232055508 NA 0.34 5.31 0.43 4.92e-7 Food antigen IgG levels; TGCT cis rs4851254 0.626 rs13001783 chr2:100689652 A/T cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs12711979 0.765 rs6705742 chr2:3820672 C/T cg17052675 chr2:3827356 NA -0.4 -7.82 -0.57 2.02e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs514406 0.861 rs35517489 chr1:53304062 G/C cg25767906 chr1:53392781 SCP2 -0.53 -6.11 -0.48 1.2e-8 Monocyte count; TGCT cis rs2486012 1.000 rs2245439 chr1:44389959 C/T cg12908607 chr1:44402522 ARTN 0.73 5.63 0.45 1.13e-7 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.832 rs3732968 chr3:10013273 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 5.93 0.47 2.76e-8 Alzheimer's disease; TGCT cis rs2840044 0.534 rs167691 chr17:33885826 G/A cg05299278 chr17:33885742 SLFN14 0.22 4.92 0.4 2.7e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs2075371 0.933 rs431306 chr7:133955974 A/T cg11752832 chr7:134001865 SLC35B4 0.68 5.89 0.47 3.32e-8 Mean platelet volume; TGCT cis rs7312933 0.612 rs10785334 chr12:42620377 A/G cg19980929 chr12:42632907 YAF2 -0.48 -5.99 -0.47 2.11e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg26566898 chr11:117069891 TAGLN 0.34 5.05 0.41 1.56e-6 Blood protein levels; TGCT cis rs12681287 0.608 rs13270090 chr8:87553297 T/A cg27223183 chr8:87520930 FAM82B 0.84 6.08 0.48 1.41e-8 Caudate activity during reward; TGCT cis rs13191362 1.000 rs35723993 chr6:163008197 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7727544 0.684 rs2516788 chr5:131715565 G/C cg24060327 chr5:131705240 SLC22A5 0.61 6.7 0.52 6.54e-10 Blood metabolite levels; TGCT cis rs854765 0.663 rs2236513 chr17:17747366 A/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.52 -0.38 1.43e-5 Total body bone mineral density; TGCT cis rs9457247 1.000 rs430477 chr6:167389851 T/C cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT trans rs208520 0.837 rs208486 chr6:66926255 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.05 -0.67 9.41e-18 Exhaled nitric oxide output; TGCT cis rs858239 0.862 rs1728292 chr7:23263474 C/G cg05602783 chr7:23145260 KLHL7 -0.62 -4.93 -0.41 2.53e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9611565 0.802 rs132916 chr22:41806768 C/G cg03806693 chr22:41940476 POLR3H 0.97 10.86 0.7 9.98e-20 Vitiligo; TGCT cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg04267008 chr7:1944627 MAD1L1 -0.37 -4.98 -0.41 2.09e-6 Bipolar disorder and schizophrenia; TGCT cis rs6912958 0.559 rs373646 chr6:88056896 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.82 0.46 4.73e-8 Monocyte percentage of white cells; TGCT cis rs617219 0.737 rs12659709 chr5:78458257 C/G cg23514016 chr5:78407564 BHMT 0.35 5.49 0.44 2.2e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4700695 0.841 rs417152 chr5:65316205 G/A cg21114390 chr5:65439923 SFRS12 0.6 4.47 0.37 1.74e-5 Facial morphology (factor 19); TGCT trans rs9329221 0.905 rs10283145 chr8:10241411 C/T cg15556689 chr8:8085844 FLJ10661 -0.77 -7.17 -0.54 5.9e-11 Neuroticism; TGCT cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs908922 0.636 rs474086 chr1:152513431 C/T cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs7119 0.667 rs907390 chr15:77902419 T/C cg27398640 chr15:77910606 LINGO1 0.32 6.72 0.52 5.98e-10 Type 2 diabetes; TGCT trans rs7618501 1.000 rs9872864 chr3:49792023 A/G cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs4788570 0.667 rs9302630 chr16:71789529 A/C cg06353428 chr16:71660113 MARVELD3 1.53 11.94 0.73 2.45e-22 Intelligence (multi-trait analysis); TGCT cis rs637571 0.557 rs1204649 chr11:65702776 A/C cg04055107 chr11:65626734 MUS81;CFL1 0.46 4.65 0.39 8.2e-6 Eosinophil percentage of white cells; TGCT cis rs4722166 0.630 rs1581497 chr7:22779503 C/A cg26061582 chr7:22766209 IL6 0.56 7.17 0.54 5.89e-11 Lung cancer; TGCT cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg06212747 chr3:49208901 KLHDC8B 0.67 6.36 0.5 3.57e-9 Menarche (age at onset); TGCT cis rs713587 0.719 rs58048722 chr2:25187825 C/T cg15423357 chr2:25149977 NA -0.58 -5.9 -0.47 3.22e-8 Body mass index in non-asthmatics; TGCT cis rs739496 0.579 rs7297760 chr12:112313688 A/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs617219 0.597 rs10474581 chr5:78578884 G/A cg05890484 chr5:78407552 BHMT -0.38 -5.17 -0.42 9.01e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9217 0.870 rs3853821 chr17:7396327 G/T cg17892169 chr17:7452644 TNFSF12;TNFSF12-TNFSF13 -0.23 -4.44 -0.37 1.99e-5 Height; TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg03407747 chr17:6899364 ALOX12 0.53 5.91 0.47 3.11e-8 Tonsillectomy; TGCT cis rs17767294 0.708 rs72848786 chr6:27980017 G/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs875971 1.000 rs1363055 chr7:65943275 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs1670533 1.000 rs13107058 chr4:1054379 G/A cg20887711 chr4:1340912 KIAA1530 0.72 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs3806843 0.576 rs246032 chr5:140332547 C/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs806215 0.526 rs58106688 chr7:127483211 T/C cg11539674 chr7:127291444 SND1 -0.36 -4.67 -0.39 7.77e-6 Type 2 diabetes; TGCT cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg26116260 chr4:7069785 GRPEL1 1.13 10.56 0.69 5.46e-19 Monocyte percentage of white cells; TGCT cis rs1887596 0.705 rs1697223 chr13:27216940 A/T cg01312412 chr13:27282625 NA -0.3 -5.35 -0.43 4.01e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs10876993 0.821 rs1629032 chr12:58038686 C/T cg15848620 chr12:58087721 OS9 -0.72 -5.78 -0.46 5.57e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7647973 1.000 rs10155014 chr3:49432321 C/T cg07636037 chr3:49044803 WDR6 0.67 5.36 0.43 3.92e-7 Menarche (age at onset); TGCT cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs2758596 0.850 rs2495270 chr1:156181530 A/G cg24450063 chr1:156163899 SLC25A44 0.9 4.67 0.39 7.64e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs6788895 0.661 rs57869178 chr3:150492826 G/C cg07663535 chr3:150480033 SIAH2 0.99 4.55 0.38 1.24e-5 Breast cancer; TGCT cis rs11105298 0.891 rs11105302 chr12:89891366 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 0.72 5.06 0.41 1.46e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT trans rs11764590 0.715 rs9639202 chr7:2087315 G/A cg25206134 chr2:45395956 NA 0.97 6.72 0.52 5.86e-10 Neuroticism; TGCT cis rs13217239 0.646 rs6937880 chr6:27000236 C/T cg02458000 chr6:26745757 NA 0.5 4.61 0.38 1e-5 Schizophrenia; TGCT cis rs240110 0.539 rs6919745 chr6:101338978 T/C cg09795085 chr6:101329169 ASCC3 0.56 4.45 0.37 1.85e-5 Neuroticism; TGCT cis rs1878931 0.559 rs1968055 chr16:3392053 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.71 6.76 0.52 4.79e-10 Body mass index (adult); TGCT cis rs7726839 0.507 rs56282020 chr5:596701 T/C cg16624210 chr5:671434 TPPP 0.44 4.83 0.4 3.89e-6 Obesity-related traits; TGCT cis rs11969893 0.649 rs9498408 chr6:101292340 C/T cg12253828 chr6:101329408 ASCC3 1.22 5.92 0.47 2.93e-8 Economic and political preferences (immigration/crime); TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg10819733 chr22:24237672 NA 0.29 4.89 0.4 3.01e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg00343986 chr7:65444356 GUSB 0.26 5.95 0.47 2.56e-8 Calcium levels; TGCT cis rs9549260 0.753 rs1986649 chr13:41178824 C/T cg21288729 chr13:41239152 FOXO1 0.67 4.68 0.39 7.31e-6 Red blood cell count; TGCT cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg26566898 chr11:117069891 TAGLN 0.35 5.09 0.42 1.27e-6 Blood protein levels; TGCT trans rs621559 0.636 rs602629 chr1:43670248 A/T cg19324027 chr2:74699582 MRPL53 0.87 6.75 0.52 5.12e-10 Telomere length; TGCT cis rs6554196 0.644 rs7655709 chr4:55499386 C/G cg02821500 chr4:54931072 CHIC2 0.48 4.71 0.39 6.54e-6 Monocyte count; TGCT cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg16049864 chr8:95962084 TP53INP1 -0.7 -9.93 -0.67 1.84e-17 Type 2 diabetes; TGCT cis rs7267979 1.000 rs2500405 chr20:25360826 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2016266 0.819 rs1976938 chr12:53661925 C/T cg16917193 chr12:54089295 NA 0.67 5.1 0.42 1.25e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs10197940 0.662 rs4335940 chr2:152275304 A/G cg06191203 chr2:152266755 RIF1 0.71 6.28 0.49 5.14e-9 Lung cancer; TGCT cis rs7119 0.667 rs907393 chr15:77903447 T/C cg27398640 chr15:77910606 LINGO1 0.32 6.76 0.52 4.86e-10 Type 2 diabetes; TGCT cis rs2797160 1.000 rs1777183 chr6:126011995 A/C cg05901451 chr6:126070800 HEY2 0.72 5.91 0.47 3.15e-8 Endometrial cancer; TGCT cis rs7568458 0.846 rs6705839 chr2:85761279 A/T cg02493740 chr2:85810744 VAMP5 -0.26 -5.04 -0.41 1.59e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4076764 1.000 rs7525643 chr1:163426283 G/A cg24596788 chr1:163392923 NA -0.17 -4.75 -0.39 5.46e-6 Motion sickness; TGCT trans rs7726839 0.526 rs55647623 chr5:567747 T/C cg11887960 chr12:57824829 NA 1.02 7.74 0.57 3.07e-12 Obesity-related traits; TGCT cis rs6840360 0.615 rs62329085 chr4:152470237 G/A cg17479576 chr4:152424074 FAM160A1 -0.71 -7.74 -0.57 2.95e-12 Intelligence (multi-trait analysis); TGCT cis rs11718455 0.960 rs3843372 chr3:43997666 C/T cg08738300 chr3:44038990 NA 0.81 6.02 0.48 1.8e-8 Coronary artery disease; TGCT cis rs10089 1.000 rs10478803 chr5:127488855 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.77 7.27 0.55 3.56e-11 Ileal carcinoids; TGCT cis rs7402982 0.625 rs4966008 chr15:99203445 A/G cg03437748 chr15:99193247 IGF1R -0.47 -4.5 -0.37 1.56e-5 Birth weight; TGCT cis rs10193935 1.000 rs12622910 chr2:42398918 C/A cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg11644478 chr21:40555479 PSMG1 -0.58 -5.1 -0.42 1.23e-6 Cognitive function; TGCT cis rs651907 0.557 rs35850993 chr3:101437433 A/G cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.69 -0.51 7.01e-10 Colorectal cancer; TGCT cis rs10197940 0.624 rs6724796 chr2:152412813 C/T cg19508488 chr2:152266495 RIF1 0.7 6.39 0.5 2.98e-9 Lung cancer; TGCT cis rs9682041 0.935 rs11923053 chr3:170095281 T/C cg11886554 chr3:170076028 SKIL 0.83 6.37 0.5 3.41e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg02675527 chr2:114030824 PAX8;LOC440839 -0.5 -6.65 -0.51 8.34e-10 Lymphocyte counts; TGCT cis rs7552404 0.731 rs5745445 chr1:76344332 G/A cg22875332 chr1:76189707 ACADM 0.7 7.11 0.54 8.18e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6089584 0.507 rs6061989 chr20:60627893 C/T cg06108461 chr20:60628389 TAF4 -0.43 -5.2 -0.42 7.98e-7 Body mass index; TGCT cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg18252515 chr7:66147081 NA -1.1 -7.23 -0.54 4.36e-11 Diabetic kidney disease; TGCT cis rs2797160 1.000 rs6910933 chr6:126017155 C/G cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs6582630 0.519 rs11519914 chr12:38287014 A/G cg26384229 chr12:38710491 ALG10B 0.78 7.01 0.53 1.36e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs10507380 0.824 rs9512632 chr13:27919034 C/G cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs854765 0.693 rs9907287 chr17:17774118 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.65 -0.57 4.87e-12 Total body bone mineral density; TGCT cis rs908922 0.651 rs1988805 chr1:152531495 T/G cg20991723 chr1:152506922 NA 0.45 6.05 0.48 1.6e-8 Hair morphology; TGCT cis rs2204008 0.728 rs11495375 chr12:38282631 G/A cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs4455778 0.536 rs38771 chr7:48940564 C/A cg26309511 chr7:48887640 NA 0.46 5.51 0.44 1.98e-7 Lung cancer in never smokers; TGCT cis rs62380364 0.565 rs13158247 chr5:88030670 C/T cg22951263 chr5:87985283 NA -0.55 -5.96 -0.47 2.46e-8 Intelligence (multi-trait analysis); TGCT cis rs11190604 0.943 rs11190574 chr10:102234331 T/C cg16005271 chr10:102321736 NA 0.46 4.69 0.39 6.96e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10479542 0.702 rs13183521 chr5:178975606 A/G cg22764044 chr5:178986830 RUFY1 -0.41 -4.49 -0.37 1.58e-5 Lung cancer; TGCT cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg13395646 chr4:1353034 KIAA1530 -0.4 -5.0 -0.41 1.93e-6 Obesity-related traits; TGCT cis rs7267979 1.000 rs2500432 chr20:25290512 A/C cg14121845 chr20:25566513 NINL 0.52 5.61 0.45 1.28e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs950776 0.518 rs28438420 chr15:78836288 A/T cg06917634 chr15:78832804 PSMA4 -0.88 -8.51 -0.61 4.66e-14 Sudden cardiac arrest; TGCT cis rs56104184 0.775 rs73061689 chr19:49397214 C/T cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs1371867 0.846 rs1660330 chr8:101305015 T/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs35146811 0.735 rs1727140 chr7:99815399 T/A cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs912057 1.000 rs1294407 chr6:6738103 C/G cg06612196 chr6:6737390 NA 0.39 4.91 0.4 2.85e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs17384381 1.000 rs36110608 chr1:85852936 A/C cg16011679 chr1:85725395 C1orf52 0.84 6.52 0.51 1.6e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs950169 0.922 rs4842941 chr15:84831312 G/C cg17173187 chr15:85201210 NMB -0.54 -5.52 -0.44 1.87e-7 Schizophrenia; TGCT trans rs2832077 0.527 rs1048546 chr21:30244877 G/T cg14791747 chr16:20752902 THUMPD1 1.01 10.53 0.69 6.61e-19 Cognitive test performance; TGCT cis rs7014346 0.767 rs7837328 chr8:128423127 A/G cg04263511 chr8:128962092 PVT1 -0.31 -4.5 -0.37 1.54e-5 Colorectal cancer; TGCT cis rs2197308 0.605 rs2387437 chr12:37919367 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.82 0.57 1.94e-12 Morning vs. evening chronotype; TGCT cis rs2486288 0.656 rs11639349 chr15:45568260 C/T cg14582100 chr15:45693742 SPATA5L1 -0.43 -4.71 -0.39 6.43e-6 Glomerular filtration rate; TGCT cis rs11690935 1.000 rs312924 chr2:172564021 A/T cg13550731 chr2:172543902 DYNC1I2 1.05 10.38 0.68 1.48e-18 Schizophrenia; TGCT cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg17554472 chr22:41940697 POLR3H 0.47 4.9 0.4 2.89e-6 Vitiligo; TGCT cis rs4631830 0.863 rs2843549 chr10:51521247 C/A cg10326726 chr10:51549505 MSMB -0.25 -4.87 -0.4 3.38e-6 Prostate-specific antigen levels; TGCT cis rs6967385 0.560 rs7790370 chr7:12353523 G/C cg20607287 chr7:12443886 VWDE 0.41 4.5 0.37 1.57e-5 Response to taxane treatment (placlitaxel); TGCT cis rs4900538 0.927 rs1190547 chr14:102905087 G/C cg18135206 chr14:102964638 TECPR2 -0.22 -5.31 -0.43 4.81e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg02675527 chr2:114030824 PAX8;LOC440839 -0.52 -6.67 -0.51 7.62e-10 Lymphocyte counts; TGCT cis rs11098499 0.698 rs4422403 chr4:120258194 C/T cg09307838 chr4:120376055 NA 0.55 5.33 0.43 4.45e-7 Corneal astigmatism; TGCT cis rs10088262 0.629 rs9918907 chr8:124816862 A/G cg20713898 chr8:124780851 FAM91A1 -0.88 -7.29 -0.55 3.13e-11 Pancreatic cancer; TGCT cis rs11098499 0.954 rs13113483 chr4:120309039 C/T cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs9300255 0.739 rs4759417 chr12:123746510 C/T cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs644799 1.000 rs596277 chr11:95566886 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.88 9.59 0.65 1.24e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs916888 0.821 rs415430 chr17:44859144 C/T cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6951245 0.554 rs58210047 chr7:1149381 G/A cg18402987 chr7:1209562 NA 0.47 4.68 0.39 7.37e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9328448 1.000 rs9502672 chr6:7991435 A/G cg13863638 chr6:7199401 RREB1 0.19 4.57 0.38 1.15e-5 Coronary artery calcification; TGCT cis rs1568889 1.000 rs58502944 chr11:28060943 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.59 0.61 3.18e-14 Bipolar disorder; TGCT cis rs1218582 0.741 rs7544528 chr1:154844585 C/T cg16680214 chr1:154839983 KCNN3 -0.43 -9.49 -0.65 2.21e-16 Prostate cancer; TGCT cis rs6912958 0.712 rs2246113 chr6:88410050 C/T cg06598631 chr6:88300029 RARS2;ORC3L -0.51 -4.93 -0.4 2.55e-6 Monocyte percentage of white cells; TGCT cis rs514406 0.536 rs878957 chr1:53197559 C/T cg01802117 chr1:53393560 SCP2 0.45 5.33 0.43 4.41e-7 Monocyte count; TGCT cis rs3820928 0.839 rs12151848 chr2:227859326 G/A cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs9549367 0.713 rs4907599 chr13:113861441 C/T cg00898013 chr13:113819073 PROZ 0.5 6.73 0.52 5.71e-10 Platelet distribution width; TGCT cis rs3806843 1.000 rs6898939 chr5:140169355 C/A cg19875535 chr5:140030758 IK 0.37 6.17 0.48 8.88e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs612683 0.536 rs1855797 chr1:101027126 A/G cg06223162 chr1:101003688 GPR88 0.33 5.59 0.45 1.39e-7 Breast cancer; TGCT cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.6 -0.65 1.15e-16 Platelet count; TGCT cis rs3091242 1.000 rs646867 chr1:25709258 A/C cg10117171 chr1:25599238 RHD -0.35 -5.72 -0.46 7.42e-8 Erythrocyte sedimentation rate; TGCT trans rs4332037 1.000 rs10240470 chr7:1949971 G/T cg10840412 chr1:235813424 GNG4 -1.06 -8.34 -0.6 1.21e-13 Bipolar disorder; TGCT cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs6728642 0.808 rs114192053 chr2:97871906 G/A cg26665480 chr2:98280029 ACTR1B -0.97 -4.85 -0.4 3.69e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs4478858 0.735 rs4949205 chr1:31800579 A/G cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs4566357 0.615 rs10178260 chr2:227914458 G/T cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs7605378 0.528 rs281787 chr2:200784238 C/T cg19045956 chr2:200819837 C2orf60;C2orf47 -0.54 -5.82 -0.46 4.81e-8 Osteoporosis; TGCT cis rs1059312 0.966 rs35907548 chr12:129282180 T/C cg09035930 chr12:129282057 SLC15A4 0.59 11.59 0.72 1.72e-21 Systemic lupus erythematosus; TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg01802117 chr1:53393560 SCP2 -0.43 -5.2 -0.42 8.03e-7 Monocyte count; TGCT cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg20607798 chr8:58055168 NA 0.61 5.06 0.41 1.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs57590327 0.503 rs13079104 chr3:81886039 A/T cg07356753 chr3:81810745 GBE1 -0.69 -6.34 -0.49 3.87e-9 Extraversion; TGCT cis rs10186029 0.667 rs6734174 chr2:213981428 A/C cg08319019 chr2:214017104 IKZF2 -0.52 -4.87 -0.4 3.39e-6 Systemic sclerosis; TGCT cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg06618935 chr21:46677482 NA -0.37 -5.83 -0.46 4.48e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs75229567 0.618 rs1599745 chr12:70186029 A/G cg10114359 chr12:70132523 RAB3IP 1.26 6.41 0.5 2.71e-9 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg14827481 chr10:134361889 INPP5A 0.31 4.99 0.41 1.99e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4689388 0.926 rs10937720 chr4:6295451 A/G cg00701064 chr4:6280414 WFS1 0.37 4.7 0.39 6.72e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs259282 0.692 rs35972270 chr19:33128457 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.62 5.84 0.46 4.38e-8 Schizophrenia; TGCT cis rs9644630 0.696 rs7828025 chr8:19314693 A/G cg06699216 chr8:19333253 CSGALNACT1 -0.25 -4.44 -0.37 1.95e-5 Oropharynx cancer; TGCT cis rs1005277 0.541 rs2263163 chr10:38389887 G/A cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs362272 0.545 rs3129308 chr4:3309272 C/T cg06533319 chr4:3265114 C4orf44 -0.25 -4.87 -0.4 3.4e-6 Serum sulfate level; TGCT cis rs11190604 1.000 rs11190551 chr10:102204734 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12048904 0.964 rs17123467 chr1:101331760 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 4.62 0.38 9.44e-6 Multiple sclerosis; TGCT cis rs12477438 0.501 rs11683107 chr2:99759235 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.86 0.8 2.64e-29 Chronic sinus infection; TGCT cis rs3008870 1.000 rs2985797 chr1:67431499 C/T cg03991309 chr1:68237761 GNG12 -0.27 -4.45 -0.37 1.9e-5 Lymphocyte percentage of white cells; TGCT cis rs7666738 0.830 rs7689495 chr4:98920152 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.11 0.48 1.21e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs28735056 0.904 rs12962619 chr18:77628832 T/C cg05926928 chr17:57297772 GDPD1 0.65 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs7000551 0.751 rs2449329 chr8:22374794 G/T cg12081754 chr8:22256438 SLC39A14 0.31 5.0 0.41 1.9e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4803468 1.000 rs4803468 chr19:41922352 A/G cg09537434 chr19:41945824 ATP5SL -0.92 -10.71 -0.69 2.31e-19 Height; TGCT cis rs8017423 0.647 rs4900037 chr14:90821478 A/G cg04374321 chr14:90722782 PSMC1 0.51 5.05 0.41 1.52e-6 Mortality in heart failure; TGCT cis rs7264396 0.635 rs6060681 chr20:34506147 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.01 -0.41 1.85e-6 Total cholesterol levels; TGCT cis rs2404602 0.669 rs9788684 chr15:77194838 A/T cg26408565 chr15:76604113 ETFA -0.36 -4.68 -0.39 7.46e-6 Blood metabolite levels; TGCT cis rs7954584 0.567 rs11043246 chr12:122368944 G/A cg21171335 chr12:122356390 WDR66 0.69 6.97 0.53 1.69e-10 Mean corpuscular volume; TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.65 0.39 8.47e-6 Prudent dietary pattern; TGCT cis rs4819052 0.851 rs2330011 chr21:46658498 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.77 0.39 5.14e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.4 -0.5 2.83e-9 Bipolar disorder and schizophrenia; TGCT cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg03264133 chr6:25882463 NA 0.86 8.95 0.63 4.38e-15 Blood metabolite levels; TGCT cis rs7208859 0.673 rs9913782 chr17:29237384 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2562456 0.917 rs2650804 chr19:21680184 A/G cg01304269 chr19:21688519 ZNF429 0.6 4.94 0.41 2.44e-6 Pain; TGCT cis rs651907 0.554 rs10470501 chr3:101630497 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.53 5.01 0.41 1.83e-6 Colorectal cancer; TGCT cis rs910316 0.763 rs175044 chr14:75472109 G/A cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.38e-7 Height; TGCT cis rs6558530 0.692 rs6558525 chr8:1702523 A/G cg09410841 chr8:1729607 CLN8 0.72 6.49 0.5 1.87e-9 Systolic blood pressure; TGCT cis rs17376456 0.778 rs72786662 chr5:93137630 C/T cg25358565 chr5:93447407 FAM172A 0.9 7.6 0.56 6.43e-12 Diabetic retinopathy; TGCT cis rs7647973 0.626 rs12715437 chr3:49751856 T/C cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg09323728 chr8:95962352 TP53INP1 -0.47 -6.18 -0.49 8.62e-9 Type 2 diabetes; TGCT cis rs7666738 0.830 rs13144771 chr4:99026935 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg11062466 chr8:58055876 NA 0.38 4.5 0.37 1.56e-5 Developmental language disorder (linguistic errors); TGCT cis rs42648 0.596 rs194523 chr7:89860574 A/T cg25739043 chr7:89950458 NA -0.5 -4.83 -0.4 3.91e-6 Homocysteine levels; TGCT cis rs4325129 1.000 rs12133664 chr1:159460890 C/T cg07417683 chr1:159440267 NA -0.44 -4.54 -0.38 1.33e-5 Obesity-related traits; TGCT cis rs7666738 0.716 rs7656233 chr4:99079237 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.64 0.45 1.08e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4843185 0.576 rs1868871 chr16:85728651 A/G cg26571870 chr16:85723150 GINS2 0.34 4.74 0.39 5.8e-6 Platelet distribution width; TGCT cis rs798766 1.000 rs3752749 chr4:1737262 T/C cg05874882 chr4:1763078 NA -0.35 -4.45 -0.37 1.86e-5 Bladder cancer;Urinary bladder cancer; TGCT cis rs6693567 0.565 rs698917 chr1:150319884 G/A cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg02458000 chr6:26745757 NA -0.5 -4.55 -0.38 1.25e-5 Schizophrenia; TGCT cis rs1008375 0.966 rs4698638 chr4:17632988 G/C cg18681998 chr4:17616180 MED28 1.01 11.55 0.72 2.15e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.44 -0.6 6.87e-14 Platelet count; TGCT cis rs2862064 0.649 rs1995377 chr5:156436679 T/A cg12943317 chr5:156479607 HAVCR1 -0.45 -5.77 -0.46 5.83e-8 Platelet count; TGCT cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT cis rs889312 0.500 rs33323 chr5:56175566 C/G cg12311346 chr5:56204834 C5orf35 -0.46 -4.97 -0.41 2.14e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs6882076 1.000 rs6882076 chr5:156390297 T/C cg12943317 chr5:156479607 HAVCR1 -0.29 -5.6 -0.45 1.3e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs3008870 1.000 rs1925412 chr1:67405057 G/A cg03991309 chr1:68237761 GNG12 0.27 4.55 0.38 1.26e-5 Lymphocyte percentage of white cells; TGCT cis rs936229 0.813 rs4886629 chr15:75072558 G/C cg10253484 chr15:75165896 SCAMP2 -0.69 -5.59 -0.45 1.4e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs12908161 1.000 rs4643294 chr15:85250253 C/T cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs7666738 0.606 rs28625338 chr4:99076996 A/G cg18180107 chr4:99064573 C4orf37 0.51 4.56 0.38 1.21e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9309473 0.687 rs12465867 chr2:73612102 C/T cg20560298 chr2:73613845 ALMS1 -0.48 -5.37 -0.43 3.68e-7 Metabolite levels; TGCT cis rs2742417 1.000 rs9829631 chr3:45740558 T/C cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7312933 0.703 rs12371615 chr12:42563989 C/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.07 0.41 1.42e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs868036 0.609 rs16951304 chr15:68089618 T/C cg27219399 chr15:67835830 MAP2K5 0.34 4.49 0.37 1.6e-5 Restless legs syndrome; TGCT cis rs7945705 0.967 rs10840148 chr11:8923528 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.19 0.42 8.23e-7 Hemoglobin concentration; TGCT cis rs2204008 0.805 rs11169513 chr12:37988640 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs11098499 0.535 rs7671759 chr4:120248094 A/C cg09307838 chr4:120376055 NA 0.61 5.78 0.46 5.57e-8 Corneal astigmatism; TGCT cis rs9814567 0.929 rs13316205 chr3:134223563 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7552404 0.924 rs1694419 chr1:76219801 C/T cg22875332 chr1:76189707 ACADM 0.61 6.28 0.49 5.17e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs42648 0.667 rs2157793 chr7:89880354 C/G cg25739043 chr7:89950458 NA -0.54 -5.04 -0.41 1.61e-6 Homocysteine levels; TGCT cis rs2228479 0.681 rs11642428 chr16:89971909 A/T cg06558623 chr16:89946397 TCF25 0.37 4.81 0.4 4.33e-6 Skin colour saturation; TGCT cis rs35306767 0.953 rs11253509 chr10:964306 C/T cg20503657 chr10:835505 NA 0.65 9.54 0.65 1.66e-16 Eosinophil percentage of granulocytes; TGCT cis rs2677744 0.688 rs3784779 chr15:91453131 C/T cg23684204 chr15:91497937 RCCD1 0.33 5.04 0.41 1.62e-6 Attention deficit hyperactivity disorder; TGCT cis rs2072499 1.000 rs2253809 chr1:156172125 T/C cg06970220 chr1:156163860 SLC25A44 0.67 5.9 0.47 3.22e-8 Testicular germ cell tumor; TGCT cis rs8180040 0.620 rs11707736 chr3:47069504 G/T cg27129171 chr3:47204927 SETD2 -0.7 -8.34 -0.6 1.22e-13 Colorectal cancer; TGCT cis rs12118280 0.581 rs545593 chr1:108720242 G/A cg11967332 chr1:108735228 SLC25A24 -0.36 -5.17 -0.42 9.18e-7 Myeloid white cell count; TGCT cis rs7552404 1.000 rs11161511 chr1:76210477 A/G cg10523679 chr1:76189770 ACADM -0.86 -9.2 -0.64 1.06e-15 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs1005277 0.540 rs2145487 chr10:38010077 A/G cg17830980 chr10:43048298 ZNF37B -0.65 -7.34 -0.55 2.4e-11 Extrinsic epigenetic age acceleration; TGCT cis rs7552404 0.960 rs12085123 chr1:76149749 G/A cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.545 rs2776311 chr21:40716885 A/G cg11890956 chr21:40555474 PSMG1 0.76 7.42 0.55 1.63e-11 Cognitive function; TGCT cis rs704 0.585 rs2227735 chr17:26693258 C/T cg10342447 chr17:26645325 TMEM97 -0.6 -6.02 -0.48 1.8e-8 Osteoprotegerin levels; TGCT cis rs2760061 0.626 rs591582 chr1:228117360 C/A cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.12e-10 Diastolic blood pressure; TGCT cis rs9443645 0.901 rs2174739 chr6:79659170 C/T cg09184832 chr6:79620586 NA 0.49 5.3 0.43 5.1e-7 Intelligence (multi-trait analysis); TGCT cis rs72781680 0.716 rs2551343 chr2:24027002 C/G cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs6570726 0.791 rs9373463 chr6:145894762 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs644799 0.544 rs1527450 chr11:95467777 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.6 5.83 0.46 4.5e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs9486715 0.867 rs211159 chr6:97023026 G/A cg06623918 chr6:96969491 KIAA0776 -1.08 -13.6 -0.77 2.39e-26 Headache; TGCT cis rs9677476 1.000 rs12621567 chr2:232118813 T/C cg07929768 chr2:232055508 NA 0.3 4.44 0.37 1.97e-5 Food antigen IgG levels; TGCT cis rs57920188 0.535 rs7412438 chr1:4095581 C/G cg20703997 chr1:4087676 NA 0.48 5.77 0.46 5.97e-8 Interleukin-17 levels; TGCT cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg27541892 chr1:1571801 CDK11B 0.35 4.65 0.39 8.39e-6 Body mass index; TGCT cis rs763014 0.932 rs35067229 chr16:649638 T/C cg00908189 chr16:619842 PIGQ 0.87 10.61 0.69 4.21e-19 Height; TGCT cis rs17401966 0.838 rs10864449 chr1:10296922 A/T cg19773385 chr1:10388646 KIF1B -0.21 -4.57 -0.38 1.14e-5 Hepatocellular carcinoma; TGCT cis rs4273100 0.688 rs4924980 chr17:19204863 T/C cg03910582 chr17:19030146 GRAPL -0.51 -6.28 -0.49 5.18e-9 Schizophrenia; TGCT cis rs921968 0.613 rs2710250 chr2:219543277 A/G cg02176678 chr2:219576539 TTLL4 -0.33 -4.45 -0.37 1.91e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs6750047 0.546 rs985257 chr2:38283228 A/T cg07380506 chr2:38303506 CYP1B1 -0.7 -6.64 -0.51 8.88e-10 Cutaneous malignant melanoma;Melanoma; TGCT cis rs4742903 0.967 rs10820610 chr9:106907819 G/A cg21169611 chr9:106856078 SMC2 0.49 4.53 0.38 1.34e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs1865760 0.963 rs3846838 chr6:25911775 T/C cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs9486719 0.843 rs2499793 chr6:96846402 A/C cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs28595532 0.764 rs115986119 chr4:119767785 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs6671200 1.000 rs71654419 chr1:95664497 C/G cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs13392177 0.660 rs12988046 chr2:219073804 A/G cg00012203 chr2:219082015 ARPC2 -0.79 -8.02 -0.58 6.73e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs9517313 0.770 rs9517301 chr13:99095088 A/G cg20487152 chr13:99095054 FARP1 -0.26 -5.14 -0.42 1.06e-6 Neuroticism; TGCT cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg06481639 chr22:41940642 POLR3H 0.62 5.59 0.45 1.4e-7 Vitiligo; TGCT cis rs514406 0.861 rs2477741 chr1:53265278 A/G cg24675658 chr1:53192096 ZYG11B 0.66 7.2 0.54 4.97e-11 Monocyte count; TGCT cis rs4499344 0.519 rs259226 chr19:33134965 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.26 0.6 1.84e-13 Mean platelet volume; TGCT cis rs17534004 1.000 rs35955426 chr13:31471381 A/G cg13251181 chr13:31481184 C13orf33 0.37 4.79 0.39 4.76e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs2361718 0.500 rs12451697 chr17:78100690 T/A cg21238619 chr17:78079768 GAA -0.33 -4.59 -0.38 1.06e-5 Yeast infection; TGCT cis rs17253792 0.822 rs79398217 chr14:56067350 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs4144743 1.000 rs34492688 chr17:45321622 C/A cg18085866 chr17:45331354 ITGB3 -0.7 -4.62 -0.38 9.41e-6 Body mass index; TGCT cis rs9894429 0.700 rs113915083 chr17:79552696 G/C cg21984481 chr17:79567631 NPLOC4 0.26 4.83 0.4 3.98e-6 Eye color traits; TGCT cis rs6921919 0.583 rs4254981 chr6:28371402 A/C cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.753 rs7657644 chr4:99057734 T/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9952991 0.941 rs60735058 chr18:12795470 T/A cg23598886 chr18:12777645 NA -0.62 -5.55 -0.45 1.64e-7 Inflammatory skin disease; TGCT cis rs473651 0.967 rs483042 chr2:239335320 A/G cg21699342 chr2:239360505 ASB1 0.17 4.79 0.4 4.69e-6 Multiple system atrophy; TGCT cis rs763121 0.853 rs5750671 chr22:39094619 A/C cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT cis rs2115630 0.967 rs7171167 chr15:85239123 A/T cg12863693 chr15:85201151 NMB -0.34 -4.64 -0.38 8.76e-6 P wave terminal force; TGCT cis rs60012524 1 rs60012524 chr2:99559117 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.67 -4.67 -0.39 7.59e-6 Chronic sinus infection; TGCT cis rs35264875 1.000 rs72928644 chr11:68849845 A/G cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg00786635 chr1:25594202 NA 0.57 5.87 0.47 3.72e-8 Erythrocyte sedimentation rate; TGCT cis rs10507380 0.943 rs41485749 chr13:27890560 C/T cg25543773 chr13:27185723 WASF3 -0.34 -4.77 -0.39 5.14e-6 Electrocardiographic traits; TGCT cis rs9457247 0.534 rs9355610 chr6:167383075 G/A cg23791538 chr6:167370224 RNASET2 0.6 5.75 0.46 6.56e-8 Crohn's disease; TGCT cis rs910187 0.605 rs2235907 chr20:45809652 A/G cg27589058 chr20:45804311 EYA2 -0.38 -8.33 -0.6 1.3e-13 Migraine; TGCT cis rs4851266 0.865 rs11695996 chr2:100854336 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.21 -0.42 7.59e-7 Educational attainment; TGCT cis rs12210905 1.000 rs72843640 chr6:27202093 T/A cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT cis rs116095464 0.558 rs6555058 chr5:226376 C/T cg22857025 chr5:266934 NA 0.32 6.12 0.48 1.16e-8 Breast cancer; TGCT cis rs1372520 0.935 rs1442152 chr4:90775649 C/A cg14346243 chr4:90757452 SNCA -0.62 -5.26 -0.43 6.17e-7 Neuroticism; TGCT cis rs11122272 0.735 rs2250749 chr1:231485763 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.37e-11 Hemoglobin concentration; TGCT cis rs12780845 0.522 rs7900703 chr10:17237617 T/C cg01003015 chr10:17271136 VIM -0.58 -5.45 -0.44 2.63e-7 Homocysteine levels; TGCT cis rs1062177 1.000 rs1062177 chr5:151184701 C/T cg12924095 chr5:151150029 G3BP1 0.35 4.97 0.41 2.16e-6 Preschool internalizing problems; TGCT cis rs9906944 0.707 rs9899931 chr17:47108282 G/A cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7949030 0.590 rs12225213 chr11:62350248 T/A cg13298116 chr11:62369859 EML3;MTA2 0.64 9.36 0.64 4.54e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7191700 0.583 rs243314 chr16:11385104 G/C cg00044050 chr16:11439710 C16orf75 1.0 13.95 0.78 3.58e-27 Multiple sclerosis; TGCT cis rs6912958 0.525 rs242262 chr6:88018057 A/C cg10393598 chr6:87862264 NA -0.31 -4.44 -0.37 2e-5 Monocyte percentage of white cells; TGCT cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs3540 0.597 rs1978150 chr15:91037041 A/G cg22089800 chr15:90895588 ZNF774 -0.76 -7.8 -0.57 2.15e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs425277 0.917 rs262656 chr1:2088754 A/C cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.43e-13 Height; TGCT cis rs295140 0.706 rs3769483 chr2:201173048 A/G cg04283868 chr2:201171347 SPATS2L 0.6 5.68 0.45 9.27e-8 QT interval; TGCT cis rs10489525 0.599 rs910622 chr1:115600424 A/G cg12756093 chr1:115239321 AMPD1 0.4 5.56 0.45 1.57e-7 Autism; TGCT cis rs13108904 0.517 rs13134568 chr4:1334289 G/A cg00684032 chr4:1343700 KIAA1530 0.22 4.73 0.39 5.89e-6 Obesity-related traits; TGCT cis rs4665809 0.549 rs72809635 chr2:26411674 G/A cg04944784 chr2:26401820 FAM59B 0.79 5.54 0.45 1.76e-7 Gut microbiome composition (summer); TGCT cis rs9611565 0.921 rs5751080 chr22:41736267 A/G cg03806693 chr22:41940476 POLR3H -0.87 -9.3 -0.64 6.07e-16 Vitiligo; TGCT cis rs11098499 0.863 rs10030660 chr4:120436704 G/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs9467711 1.000 rs6908156 chr6:26322861 C/T cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs151997 0.569 rs10035173 chr5:50276059 C/G cg06027927 chr5:50259733 NA 0.56 5.5 0.44 2.07e-7 Callous-unemotional behaviour; TGCT cis rs13256369 0.950 rs13248096 chr8:8577476 C/T cg18904891 chr8:8559673 CLDN23 0.63 5.9 0.47 3.31e-8 Obesity-related traits; TGCT cis rs6977660 0.652 rs10486362 chr7:19755224 A/G cg07541023 chr7:19748670 TWISTNB -1.15 -7.28 -0.55 3.33e-11 Thyroid stimulating hormone; TGCT cis rs3087591 1.000 rs12948444 chr17:29443614 A/G cg24425628 chr17:29625626 OMG;NF1 0.47 7.58 0.56 7.13e-12 Hip circumference; TGCT cis rs769267 0.895 rs2315279 chr19:19479936 C/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.68 -5.79 -0.46 5.47e-8 Tonsillectomy; TGCT cis rs669446 0.558 rs609171 chr1:44110216 A/C cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs8078723 0.866 rs3935280 chr17:38189055 A/G cg17467752 chr17:38218738 THRA -0.62 -6.06 -0.48 1.49e-8 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs25422 0.938 rs62421538 chr6:118729703 A/T cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Renal cell carcinoma; TGCT cis rs709400 0.633 rs45441198 chr14:104002611 T/C cg26031613 chr14:104095156 KLC1 0.86 9.6 0.65 1.19e-16 Body mass index; TGCT cis rs12681288 0.862 rs2701899 chr8:1019581 G/A cg06709756 chr8:1339049 NA -0.23 -4.57 -0.38 1.15e-5 Schizophrenia; TGCT cis rs200810 0.694 rs4839913 chr6:98019234 C/G cg17774634 chr6:97730494 C6orf167;MIR548H3 -0.67 -4.54 -0.38 1.32e-5 Body mass index; TGCT cis rs6912958 1.000 rs2223880 chr6:88167897 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.64 -6.31 -0.49 4.58e-9 Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs6831219 chr4:98993576 C/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7945705 0.935 rs10769971 chr11:8925276 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.1 0.42 1.24e-6 Hemoglobin concentration; TGCT cis rs9653442 0.805 rs7608424 chr2:100796543 G/T cg22139774 chr2:100720529 AFF3 -0.43 -7.48 -0.56 1.16e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs6671200 0.573 rs3738171 chr1:95699594 A/G cg03123541 chr1:95699097 RWDD3 -0.83 -7.18 -0.54 5.78e-11 Stearic acid (18:0) levels; TGCT cis rs78545713 1.000 rs114970164 chr6:26241993 G/C cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.72 -4.67 -0.39 7.66e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs11690462 0.963 rs34436433 chr2:26592534 T/G cg04726446 chr2:26624865 C2orf39 0.42 4.59 0.38 1.06e-5 Coronary artery disease; TGCT cis rs9682041 0.740 rs6444929 chr3:170150076 C/T cg07589077 chr3:170072950 NA 0.32 4.6 0.38 1.02e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.53 4.55 0.38 1.26e-5 Urate levels; TGCT cis rs763121 0.813 rs2179143 chr22:39037984 A/G cg06022373 chr22:39101656 GTPBP1 0.74 7.32 0.55 2.74e-11 Menopause (age at onset); TGCT cis rs155076 1.000 rs261431 chr13:21865738 A/G cg07022442 chr13:21864356 NA -0.29 -4.58 -0.38 1.13e-5 White matter hyperintensity burden; TGCT cis rs3809566 1.000 rs4774471 chr15:63332645 A/T cg08198488 chr15:63333792 TPM1 0.34 4.95 0.41 2.41e-6 Platelet count; TGCT cis rs694739 0.536 rs11231740 chr11:64046641 C/T cg23796481 chr11:64053134 BAD;GPR137 -0.55 -5.34 -0.43 4.33e-7 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg18252515 chr7:66147081 NA 1.18 7.05 0.53 1.11e-10 Diabetic kidney disease; TGCT cis rs4900538 0.963 rs4906205 chr14:102932447 A/G cg18135206 chr14:102964638 TECPR2 0.22 5.62 0.45 1.22e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2120019 0.938 rs13056 chr15:75312187 A/G cg09165964 chr15:75287851 SCAMP5 -1.14 -10.33 -0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs1903068 0.657 rs41408948 chr4:55992025 G/A cg09978860 chr4:56023921 NA 0.54 5.48 0.44 2.26e-7 Endometriosis; TGCT cis rs394563 0.591 rs237026 chr6:149720681 G/A cg11245181 chr6:149772854 ZC3H12D -0.28 -4.52 -0.38 1.43e-5 Dupuytren's disease; TGCT cis rs6430585 0.528 rs12476127 chr2:136763242 A/G cg07169764 chr2:136633963 MCM6 1.27 12.64 0.75 4.76e-24 Corneal structure; TGCT cis rs875971 0.825 rs66981195 chr7:66079035 C/A cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.89e-6 Aortic root size; TGCT cis rs4321325 0.733 rs13421996 chr2:127934812 G/T cg09760422 chr2:128146352 NA 0.44 4.55 0.38 1.26e-5 Protein C levels; TGCT cis rs2980439 0.517 rs17594065 chr8:8105405 T/C cg08975724 chr8:8085496 FLJ10661 -0.54 -4.84 -0.4 3.84e-6 Neuroticism; TGCT cis rs12681288 0.676 rs1562925 chr8:1010894 A/G cg04851639 chr8:1020857 NA -0.27 -4.51 -0.38 1.48e-5 Schizophrenia; TGCT cis rs597539 0.652 rs501799 chr11:68631240 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.39 0.6 9.13e-14 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1008375 0.932 rs6844593 chr4:17659039 T/C cg18681998 chr4:17616180 MED28 0.98 10.79 0.7 1.49e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1008375 1.000 rs2286771 chr4:17643848 G/A cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6558530 0.932 rs6558531 chr8:1707566 A/G cg09410841 chr8:1729607 CLN8 0.91 10.27 0.68 2.86e-18 Systolic blood pressure; TGCT cis rs9926296 0.706 rs2159115 chr16:89831819 A/G cg27121462 chr16:89883253 FANCA 0.56 5.33 0.43 4.54e-7 Vitiligo; TGCT cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg03517284 chr6:25882590 NA -0.58 -6.03 -0.48 1.76e-8 Blood metabolite levels; TGCT cis rs9348729 1 rs9348729 chr6:26664268 T/C cg15659132 chr6:26577336 NA -0.73 -5.25 -0.43 6.5e-7 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.850 rs10055295 chr5:243749 G/A cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs73099903 0.611 rs7306523 chr12:53393964 A/G cg24505307 chr12:53448429 TENC1 0.37 4.92 0.4 2.7e-6 Systolic blood pressure; TGCT cis rs7666738 0.800 rs13107147 chr4:99028753 C/T cg17366294 chr4:99064904 C4orf37 0.72 7.54 0.56 8.52e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs56117870 chr4:119766583 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs4665809 1.000 rs6546727 chr2:26275282 C/T cg04944784 chr2:26401820 FAM59B -0.67 -6.09 -0.48 1.32e-8 Gut microbiome composition (summer); TGCT cis rs79349575 0.655 rs62078384 chr17:47044463 C/T cg07967210 chr17:47022446 SNF8 0.45 6.27 0.49 5.37e-9 Type 2 diabetes; TGCT cis rs2033711 0.840 rs10423138 chr19:58928302 T/C cg12042659 chr19:58951599 ZNF132 0.52 4.66 0.39 7.87e-6 Uric acid clearance; TGCT cis rs7772486 0.754 rs6570708 chr6:145989428 C/T cg23711669 chr6:146136114 FBXO30 -0.92 -10.52 -0.69 6.88e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs7772486 0.806 rs7740785 chr6:146171299 C/A cg23711669 chr6:146136114 FBXO30 0.87 9.51 0.65 1.93e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs950169 0.763 rs35372971 chr15:84941795 G/A cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs2013441 0.965 rs2703808 chr17:20109665 A/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs236907 0.859 rs56365362 chr1:171752193 G/A cg20598894 chr1:171756153 METTL13 -0.19 -4.47 -0.37 1.72e-5 Mean platelet volume; TGCT cis rs3806843 0.933 rs2337987 chr5:140188383 T/G cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs10876993 0.890 rs12302351 chr12:58062590 T/C cg15848620 chr12:58087721 OS9 -0.71 -5.63 -0.45 1.13e-7 Celiac disease or Rheumatoid arthritis; TGCT cis rs3845702 0.736 rs72962517 chr2:180861452 G/A cg01881094 chr2:180872142 CWC22 1.06 6.66 0.51 8.12e-10 Schizophrenia; TGCT cis rs3796352 0.892 rs9756317 chr3:53088815 T/C cg27565382 chr3:53032988 SFMBT1 -0.42 -4.79 -0.4 4.61e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs682748 0.846 rs12186747 chr5:17155432 G/A cg23987134 chr5:17158319 LOC285696 -0.23 -5.48 -0.44 2.22e-7 Hippocampal atrophy; TGCT cis rs3806843 0.900 rs2261651 chr5:140136804 A/C cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 9.04e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg05368731 chr17:41323189 NBR1 1.21 14.53 0.79 1.5e-28 Menopause (age at onset); TGCT cis rs12615966 0.932 rs72830462 chr2:105394600 C/T cg16465502 chr2:105461796 NA 0.8 5.14 0.42 1.06e-6 Pancreatic cancer; TGCT cis rs1059312 0.522 rs3825181 chr12:129279264 G/A cg09035930 chr12:129282057 SLC15A4 -0.49 -6.99 -0.53 1.54e-10 Systemic lupus erythematosus; TGCT cis rs858239 0.899 rs7794684 chr7:23310805 A/G cg05602783 chr7:23145260 KLHL7 -0.66 -5.26 -0.43 6.04e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg24531977 chr5:56204891 C5orf35 -0.75 -7.31 -0.55 2.87e-11 Initial pursuit acceleration; TGCT cis rs806215 0.547 rs59140894 chr7:127430797 C/T cg11539674 chr7:127291444 SND1 -0.36 -4.6 -0.38 1.02e-5 Type 2 diabetes; TGCT cis rs10883723 0.810 rs913025 chr10:104276043 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9646954 0.560 rs4149507 chr2:101032745 C/T cg08017756 chr2:100939284 LONRF2 -0.29 -4.58 -0.38 1.11e-5 Intelligence (multi-trait analysis); TGCT cis rs4631830 0.720 rs898343 chr10:51505403 A/G cg10326726 chr10:51549505 MSMB 0.23 4.53 0.38 1.35e-5 Prostate-specific antigen levels; TGCT cis rs6671200 0.573 rs6666528 chr1:95697490 C/A cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs17253792 0.822 rs76918910 chr14:56058762 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs17433780 0.836 rs61798917 chr1:89506093 G/A cg09516651 chr1:89888402 LOC400759 0.25 4.99 0.41 2.01e-6 Carotid intima media thickness; TGCT cis rs7267979 0.549 rs6138536 chr20:25182648 A/G cg16686733 chr20:25566563 NINL 0.53 5.39 0.44 3.48e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6882046 0.513 rs42850 chr5:88019474 G/A cg24804195 chr5:87968844 LOC645323 -0.57 -5.57 -0.45 1.5e-7 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2710642 0.927 rs6705798 chr2:63259881 C/T cg17519650 chr2:63277830 OTX1 0.66 5.73 0.46 7.17e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs1505368 0.817 rs6435701 chr2:213283512 A/G cg16329650 chr2:213403929 ERBB4 0.66 6.59 0.51 1.11e-9 Symmetrical dimethylarginine levels; TGCT cis rs739401 0.572 rs410820 chr11:3080102 G/A cg25174290 chr11:3078921 CARS 0.54 5.22 0.42 7.36e-7 Longevity; TGCT cis rs7714584 1.000 rs2344180 chr5:150267357 T/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs9928842 0.765 rs2870467 chr16:75223881 A/G cg09066997 chr16:75300724 BCAR1 0.26 4.61 0.38 9.91e-6 Alcoholic chronic pancreatitis; TGCT cis rs35306767 0.623 rs34034003 chr10:1143435 G/A cg26597838 chr10:835615 NA 0.47 4.95 0.41 2.37e-6 Eosinophil percentage of granulocytes; TGCT cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg11494091 chr17:61959527 GH2 0.43 7.52 0.56 9.81e-12 Height; TGCT cis rs2760061 0.819 rs964941 chr1:228193857 G/A cg02753203 chr1:228287806 NA 0.3 5.71 0.46 7.95e-8 Diastolic blood pressure; TGCT cis rs7647973 0.696 rs3087866 chr3:49054692 A/G cg07636037 chr3:49044803 WDR6 0.8 6.66 0.51 8.03e-10 Menarche (age at onset); TGCT cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg09222892 chr1:25734099 RHCE 0.42 7.15 0.54 6.72e-11 Erythrocyte sedimentation rate; TGCT cis rs877282 0.898 rs12357016 chr10:765675 C/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs7017914 0.905 rs2732106 chr8:71923839 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.2e-6 Bone mineral density; TGCT cis rs6424115 0.594 rs10799802 chr1:24009544 C/T cg15997130 chr1:24165203 NA 0.55 5.08 0.42 1.34e-6 Immature fraction of reticulocytes; TGCT cis rs9948 0.655 rs3731940 chr2:97377883 A/G cg01990225 chr2:97406019 LMAN2L 1.01 5.13 0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT trans rs7726839 0.561 rs11955068 chr5:582324 C/T cg25482853 chr8:67687455 SGK3 1.07 8.9 0.62 5.55e-15 Obesity-related traits; TGCT cis rs61160187 0.582 rs17332824 chr5:60166187 C/G cg02684056 chr5:59996105 DEPDC1B -0.47 -4.44 -0.37 1.99e-5 Educational attainment (years of education);Educational attainment (college completion); TGCT cis rs2832191 0.791 rs2832196 chr21:30497412 G/A cg24692254 chr21:30365293 RNF160 -0.86 -9.11 -0.63 1.83e-15 Dental caries; TGCT cis rs7819412 0.807 rs10105315 chr8:10932203 G/C cg21775007 chr8:11205619 TDH -0.51 -4.78 -0.39 4.86e-6 Triglycerides; TGCT cis rs9549260 0.564 rs4943812 chr13:41335816 T/C cg21288729 chr13:41239152 FOXO1 0.95 9.2 0.64 1.08e-15 Red blood cell count; TGCT cis rs1062177 0.826 rs2915873 chr5:151156658 G/A cg00977110 chr5:151150581 G3BP1 0.4 4.62 0.38 9.49e-6 Preschool internalizing problems; TGCT cis rs2836974 0.583 rs8132993 chr21:40716410 T/C cg17971929 chr21:40555470 PSMG1 0.62 5.52 0.44 1.92e-7 Cognitive function; TGCT cis rs7927592 0.513 rs531163 chr11:68194496 A/G cg16797656 chr11:68205561 LRP5 0.28 5.07 0.41 1.44e-6 Total body bone mineral density; TGCT cis rs854765 0.547 rs2955383 chr17:17941364 A/G cg09796270 chr17:17721594 SREBF1 0.26 5.15 0.42 9.93e-7 Total body bone mineral density; TGCT cis rs17826219 0.636 rs79565452 chr17:29142841 T/C cg13385521 chr17:29058706 SUZ12P 0.79 4.8 0.4 4.47e-6 Body mass index; TGCT cis rs950027 0.620 rs2486274 chr15:45666228 G/T cg14582100 chr15:45693742 SPATA5L1 0.48 6.07 0.48 1.44e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs7666738 0.830 rs3911282 chr4:99037602 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7727544 0.901 rs55633655 chr5:131598756 T/G cg24060327 chr5:131705240 SLC22A5 -0.6 -6.4 -0.5 2.92e-9 Blood metabolite levels; TGCT cis rs11190604 1.000 rs11190599 chr10:102295420 C/T cg23241863 chr10:102295624 HIF1AN 0.67 5.12 0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2933343 0.729 rs1680781 chr3:128612830 C/A cg11901034 chr3:128598214 ACAD9 -0.67 -6.55 -0.51 1.35e-9 IgG glycosylation; TGCT cis rs10114408 0.959 rs10739963 chr9:96650907 G/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs3008870 0.583 rs3008861 chr1:67396222 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.98 8.3 0.6 1.46e-13 Lymphocyte percentage of white cells; TGCT cis rs644799 0.965 rs1944080 chr11:95503636 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.82 0.7 1.31e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9611565 0.649 rs5758434 chr22:42116163 G/A cg13695892 chr22:41940480 POLR3H 0.83 8.18 0.59 2.79e-13 Vitiligo; TGCT cis rs9527 0.590 rs10883834 chr10:104881402 T/C cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs9527 0.590 rs3861984 chr10:104916980 T/C cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.09e-7 Arsenic metabolism; TGCT cis rs12291225 0.545 rs11023187 chr11:14345559 T/G cg19336497 chr11:14380999 RRAS2 -0.45 -7.25 -0.55 3.87e-11 Sense of smell; TGCT cis rs6988636 1.000 rs58189203 chr8:124184739 G/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1555895 0.566 rs1057304 chr10:853106 T/C cg02193355 chr10:851439 NA 0.24 5.33 0.43 4.45e-7 Survival in rectal cancer; TGCT trans rs10504390 0.656 rs74675840 chr8:66485845 G/A cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.26e-10 IgG glycosylation; TGCT cis rs752092 1.000 rs11636578 chr15:101787969 T/C cg19997662 chr15:101784653 CHSY1 -0.3 -5.72 -0.46 7.64e-8 Corneal structure; TGCT trans rs1005277 0.579 rs176886 chr10:38403974 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs5167 0.566 rs2075620 chr19:45480037 C/T cg13119609 chr19:45449297 APOC2 -0.23 -4.65 -0.39 8.26e-6 Blood protein levels; TGCT cis rs2730260 0.500 rs73169244 chr7:158887293 T/C cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs4803468 0.967 rs3213860 chr19:41920211 T/C cg09537434 chr19:41945824 ATP5SL -0.9 -10.59 -0.69 4.65e-19 Height; TGCT cis rs709400 0.550 rs11626905 chr14:104016066 C/T cg12935359 chr14:103987150 CKB -0.46 -6.02 -0.48 1.87e-8 Body mass index; TGCT cis rs7829975 0.871 rs777709 chr8:8583872 T/C cg06636001 chr8:8085503 FLJ10661 -0.59 -4.91 -0.4 2.78e-6 Mood instability; TGCT cis rs903263 0.901 rs12750691 chr1:84595520 C/T cg09664975 chr1:84543551 PRKACB 0.5 4.75 0.39 5.62e-6 Breast cancer (male); TGCT cis rs9487051 0.714 rs6930733 chr6:109631587 T/C cg01475377 chr6:109611718 NA -0.31 -4.73 -0.39 6.12e-6 Reticulocyte fraction of red cells; TGCT cis rs826838 0.933 rs980573 chr12:39127811 T/C cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs12134245 1.000 rs12134245 chr1:92021464 C/T cg25838465 chr1:92012736 NA -0.41 -6.63 -0.51 9.27e-10 Breast cancer; TGCT cis rs6703348 0.560 rs863018 chr1:159215326 C/T cg07961479 chr1:159825173 VSIG8;C1orf204 0.25 4.85 0.4 3.61e-6 Monocyte chemoattractant protein-1 levels; TGCT cis rs62103177 0.714 rs7227962 chr18:77603283 T/G cg12964065 chr18:77638022 KCNG2 0.33 4.63 0.38 9.06e-6 Opioid sensitivity; TGCT cis rs10782582 0.593 rs74090712 chr1:76189098 A/G cg22875332 chr1:76189707 ACADM -0.51 -5.75 -0.46 6.54e-8 Daytime sleep phenotypes; TGCT cis rs9814567 0.762 rs13093893 chr3:134292131 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.8 6.08 0.48 1.38e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6952808 0.823 rs58222895 chr7:1885064 G/A cg22963979 chr7:1858916 MAD1L1 -0.32 -4.78 -0.39 4.9e-6 Bipolar disorder and schizophrenia; TGCT cis rs7523273 0.526 rs2724375 chr1:207997973 C/A cg22525895 chr1:207977042 MIR29B2 -0.53 -9.19 -0.64 1.14e-15 Schizophrenia; TGCT cis rs3733585 0.579 rs4235353 chr4:10122934 C/T cg00071950 chr4:10020882 SLC2A9 -0.51 -5.29 -0.43 5.33e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1971762 0.563 rs11170645 chr12:54079080 G/T cg16917193 chr12:54089295 NA 1.37 17.65 0.85 1.25e-35 Height; TGCT cis rs4727027 0.704 rs1123992 chr7:148907201 C/G cg23583168 chr7:148888333 NA -0.78 -9.9 -0.66 2.24e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs11098499 0.863 rs13140391 chr4:120503437 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs7937682 0.889 rs11213971 chr11:111529829 A/G cg09085632 chr11:111637200 PPP2R1B -1.1 -11.66 -0.72 1.13e-21 Primary sclerosing cholangitis; TGCT cis rs12950390 0.853 rs4793647 chr17:45854090 G/C cg06532163 chr17:45867833 NA 0.37 5.87 0.47 3.74e-8 IgG glycosylation; TGCT cis rs17030434 0.784 rs8180349 chr4:154657038 T/C cg14289246 chr4:154710475 SFRP2 -0.85 -7.21 -0.54 4.87e-11 Electrocardiographic conduction measures; TGCT cis rs11785400 0.793 rs35985277 chr8:143736137 C/T cg10596483 chr8:143751796 JRK 0.53 5.27 0.43 5.89e-7 Schizophrenia; TGCT cis rs4478858 0.735 rs6687819 chr1:31801112 G/A cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg27588902 chr6:42928151 GNMT -0.56 -6.86 -0.52 2.94e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1971762 0.583 rs10876485 chr12:54087648 C/T cg16917193 chr12:54089295 NA -1.27 -17.05 -0.84 2.6e-34 Height; TGCT cis rs7085104 0.632 rs6162 chr10:104596981 G/A cg15744005 chr10:104629667 AS3MT -0.43 -5.37 -0.43 3.77e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs9611565 0.559 rs5758397 chr22:42019251 C/T cg03806693 chr22:41940476 POLR3H 1.06 11.19 0.71 1.58e-20 Vitiligo; TGCT cis rs904251 0.797 rs1776460 chr6:37485484 A/G cg25019722 chr6:37503610 NA -0.48 -6.63 -0.51 9.26e-10 Cognitive performance; TGCT cis rs11030122 0.645 rs11493482 chr11:4034772 A/G cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs67180937 0.553 rs3008629 chr1:222835930 T/C cg09820183 chr1:222886073 C1orf58;AIDA 0.73 4.47 0.37 1.77e-5 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Coronary artery disease; TGCT cis rs36051895 0.632 rs10217652 chr9:5119939 A/G cg02405213 chr9:5042618 JAK2 -0.74 -10.47 -0.68 9.14e-19 Pediatric autoimmune diseases; TGCT cis rs7607369 0.596 rs10165754 chr2:219287370 A/G cg02176678 chr2:219576539 TTLL4 -0.5 -6.37 -0.5 3.41e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs9911578 0.900 rs4793593 chr17:56892699 C/G cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs3540 0.960 rs11857092 chr15:90960115 T/C cg22089800 chr15:90895588 ZNF774 0.73 6.81 0.52 3.77e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs514475 0.526 rs12194668 chr6:137956734 C/T cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs4803468 1.000 rs11670668 chr19:41920454 G/C cg09537434 chr19:41945824 ATP5SL -0.9 -10.59 -0.69 4.65e-19 Height; TGCT cis rs7666738 0.830 rs1813251 chr4:98921170 A/G cg05340658 chr4:99064831 C4orf37 0.53 6.11 0.48 1.17e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs8032315 0.965 rs12906125 chr15:91427612 G/A cg03209642 chr15:91427605 FES 0.52 4.92 0.4 2.67e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2721195 0.967 rs1985022 chr8:145684031 C/T cg11211951 chr8:145729740 GPT 0.23 5.38 0.43 3.64e-7 Age at first birth; TGCT cis rs2439831 0.681 rs11858152 chr15:43634196 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.91 6.89 0.53 2.52e-10 Lung cancer in ever smokers; TGCT cis rs11043280 0.703 rs11043275 chr12:122402723 T/C cg21016266 chr12:122356598 WDR66 0.47 5.97 0.47 2.36e-8 Mean platelet volume; TGCT cis rs4711350 0.765 rs2395446 chr6:33743264 C/T cg13859433 chr6:33739653 LEMD2 -0.34 -5.22 -0.42 7.46e-7 Schizophrenia; TGCT cis rs739496 0.947 rs587914 chr12:111943004 T/C cg10833066 chr12:111807467 FAM109A 0.37 5.59 0.45 1.4e-7 Platelet count; TGCT cis rs2073300 1.000 rs6132625 chr20:23444671 C/T cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7640424 0.826 rs7635063 chr3:107818777 C/T cg09227934 chr3:107805635 CD47 -0.23 -4.45 -0.37 1.87e-5 Body mass index; TGCT cis rs2228479 0.850 rs2239358 chr16:89827330 C/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs9952991 0.566 rs579052 chr18:12858610 T/C cg23544223 chr18:12777786 NA 0.55 4.88 0.4 3.22e-6 Inflammatory skin disease; TGCT cis rs301043 0.500 rs301010 chr12:95870154 A/G cg07805603 chr12:95869602 METAP2 0.41 5.19 0.42 8.35e-7 Immature fraction of reticulocytes; TGCT cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg15659132 chr6:26577336 NA 0.86 10.87 0.7 9.57e-20 Intelligence (multi-trait analysis); TGCT cis rs709400 0.770 rs7142883 chr14:104066645 G/A cg26031613 chr14:104095156 KLC1 1.15 16.05 0.82 4.72e-32 Body mass index; TGCT cis rs17221829 0.733 rs1873083 chr11:89396810 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.57 -0.38 1.18e-5 Anxiety in major depressive disorder; TGCT cis rs2535633 0.631 rs2581827 chr3:52966558 C/T cg11645453 chr3:52864694 ITIH4 -0.29 -5.21 -0.42 7.57e-7 Body mass index; TGCT cis rs7264396 0.790 rs6060541 chr20:34248066 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs3820928 1.000 rs10204368 chr2:227774244 G/C cg11843606 chr2:227700838 RHBDD1 -0.54 -4.82 -0.4 4.12e-6 Pulmonary function; TGCT cis rs12497850 0.931 rs11924597 chr3:48937790 T/C cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs7772486 0.754 rs702306 chr6:145991029 T/C cg13319975 chr6:146136371 FBXO30 0.55 4.99 0.41 2.03e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs950027 0.549 rs1719250 chr15:45609773 A/G cg14582100 chr15:45693742 SPATA5L1 0.45 5.55 0.45 1.68e-7 Response to fenofibrate (adiponectin levels); TGCT cis rs11030122 0.702 rs1013351 chr11:3952303 A/T cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs9549367 0.713 rs1323315 chr13:113859658 T/C cg18105134 chr13:113819100 PROZ 0.46 8.76 0.62 1.2e-14 Platelet distribution width; TGCT cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.62 -0.38 9.3e-6 Intelligence (multi-trait analysis); TGCT cis rs11098499 0.954 rs10005644 chr4:120298477 T/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs9443645 0.901 rs9448580 chr6:79551812 C/G cg05283184 chr6:79620031 NA -0.2 -4.67 -0.39 7.71e-6 Intelligence (multi-trait analysis); TGCT cis rs644799 0.509 rs580181 chr11:95643040 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.49 4.97 0.41 2.17e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs9430161 0.579 rs7542354 chr1:11040385 G/A cg02454025 chr1:11042201 C1orf127 0.97 12.71 0.75 3.27e-24 Ewing sarcoma; TGCT cis rs11249608 0.548 rs6880315 chr5:178452502 G/A cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs10751667 0.643 rs10902238 chr11:944810 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs2742417 0.603 rs2064063 chr3:45759924 T/A cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6582630 0.502 rs11181475 chr12:38348922 G/A cg26384229 chr12:38710491 ALG10B 0.78 6.94 0.53 1.91e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs832540 0.552 rs252924 chr5:56205643 A/G cg24531977 chr5:56204891 C5orf35 -0.6 -5.74 -0.46 6.92e-8 Coronary artery disease; TGCT cis rs13191362 0.507 rs6936804 chr6:163069424 A/T cg06582575 chr6:163149167 PACRG;PARK2 -0.59 -5.37 -0.43 3.66e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12579753 0.879 rs11115008 chr12:82164859 C/T cg07988820 chr12:82153109 PPFIA2 -0.69 -7.56 -0.56 7.78e-12 Resting heart rate; TGCT cis rs453301 0.686 rs3989373 chr8:8911308 G/T cg06636001 chr8:8085503 FLJ10661 -0.7 -5.94 -0.47 2.74e-8 Joint mobility (Beighton score); TGCT cis rs9611565 0.879 rs5758311 chr22:41759375 G/T cg13695892 chr22:41940480 POLR3H -0.85 -8.45 -0.6 6.59e-14 Vitiligo; TGCT cis rs7772486 0.806 rs4075695 chr6:146250959 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -5.16 -0.42 9.33e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6674176 0.597 rs3762422 chr1:44400532 T/A cg12908607 chr1:44402522 ARTN -0.74 -9.33 -0.64 5.3e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2204008 0.571 rs8175738 chr12:38311234 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs11098499 0.708 rs1546506 chr4:120241240 T/C cg09307838 chr4:120376055 NA 0.61 5.89 0.47 3.33e-8 Corneal astigmatism; TGCT cis rs66573146 1.000 rs7686186 chr4:6986094 C/T cg05069807 chr4:6945702 TBC1D14 0.35 4.94 0.41 2.51e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4635969 1.000 rs4635969 chr5:1308552 C/T cg07493874 chr5:1342172 CLPTM1L -0.25 -4.78 -0.39 4.9e-6 Testicular germ cell tumor;Testicular germ cell cancer; TGCT cis rs72781680 0.716 rs6731314 chr2:24048338 C/T cg08917208 chr2:24149416 ATAD2B -0.78 -4.85 -0.4 3.62e-6 Lymphocyte counts; TGCT cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg00484396 chr16:3507460 NAT15 0.43 6.62 0.51 9.89e-10 Tuberculosis; TGCT trans rs7824557 0.689 rs10481454 chr8:11109303 C/G cg06636001 chr8:8085503 FLJ10661 -0.83 -6.89 -0.53 2.46e-10 Retinal vascular caliber; TGCT cis rs2282802 0.660 rs7726176 chr5:139547971 T/A cg01081189 chr5:139537190 NA -0.3 -5.37 -0.43 3.82e-7 Intelligence (multi-trait analysis); TGCT cis rs514406 0.679 rs541852 chr1:53256834 A/G cg16325326 chr1:53192061 ZYG11B -0.58 -6.4 -0.5 2.86e-9 Monocyte count; TGCT cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs9926296 0.656 rs2376882 chr16:89827002 T/C cg26513180 chr16:89883248 FANCA 0.69 6.79 0.52 4.23e-10 Vitiligo; TGCT cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg13866156 chr1:1669148 SLC35E2 -0.22 -5.16 -0.42 9.35e-7 Body mass index; TGCT cis rs2361718 0.967 rs2361719 chr17:78103403 A/G cg09238746 chr17:78121135 EIF4A3 0.51 4.58 0.38 1.12e-5 Yeast infection; TGCT cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.59 -5.45 -0.44 2.58e-7 Height; TGCT cis rs9326248 0.520 rs236919 chr11:117095361 A/G cg01368799 chr11:117014884 PAFAH1B2 0.58 5.35 0.43 4.05e-7 Blood protein levels; TGCT cis rs7552404 0.731 rs2029683 chr1:76341643 T/G cg03433033 chr1:76189801 ACADM -0.76 -7.76 -0.57 2.66e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.962 rs2865986 chr4:99067907 A/G cg18180107 chr4:99064573 C4orf37 0.56 4.54 0.38 1.33e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs3790515 1.000 rs3790515 chr1:151786372 A/G cg07092448 chr1:151763213 TDRKH 1.0 4.5 0.37 1.54e-5 Depressive symptoms (SSRI exposure interaction); TGCT cis rs6062496 0.609 rs67311561 chr20:62304762 A/G cg27236539 chr20:62289627 RTEL1 0.69 6.5 0.5 1.73e-9 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs72615157 0.612 rs7786505 chr7:99817585 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.95 0.41 2.34e-6 Lung function (FEV1/FVC); TGCT cis rs7772486 0.686 rs9399564 chr6:146078907 C/T cg23711669 chr6:146136114 FBXO30 -0.9 -10.29 -0.68 2.52e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs17401966 0.838 rs17034643 chr1:10332102 A/G cg19773385 chr1:10388646 KIF1B 0.21 4.55 0.38 1.25e-5 Hepatocellular carcinoma; TGCT cis rs7829975 0.573 rs7842359 chr8:8797078 T/G cg15556689 chr8:8085844 FLJ10661 -0.69 -6.14 -0.48 1.01e-8 Mood instability; TGCT cis rs4242434 0.927 rs746011 chr8:22457804 C/T cg03733263 chr8:22462867 KIAA1967 1.16 19.41 0.87 2.12e-39 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs6028335 0.502 rs7265661 chr20:37586842 G/T cg27552599 chr20:37590471 DHX35 0.37 4.47 0.37 1.72e-5 Alcohol and nicotine co-dependence; TGCT cis rs4631830 0.900 rs10763534 chr10:51534920 C/T cg10326726 chr10:51549505 MSMB -0.27 -5.46 -0.44 2.54e-7 Prostate-specific antigen levels; TGCT cis rs4319547 1.000 rs7309390 chr12:123110422 A/G cg23029597 chr12:123009494 RSRC2 -0.3 -4.82 -0.4 4.14e-6 Body mass index; TGCT cis rs6840360 0.593 rs10222925 chr4:152690215 A/G cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.62e-8 Intelligence (multi-trait analysis); TGCT cis rs8031584 0.678 rs36047941 chr15:31159235 A/G cg14829155 chr15:31115871 NA -0.36 -4.72 -0.39 6.14e-6 Huntington's disease progression; TGCT cis rs12142240 0.698 rs66516678 chr1:46810112 G/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs7611238 0.560 rs9859902 chr3:195065255 T/C cg27323046 chr3:195102265 ACAP2 0.35 4.75 0.39 5.5e-6 Body mass index; TGCT cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.54 4.55 0.38 1.26e-5 Height; TGCT cis rs62244186 0.659 rs9855433 chr3:44468065 C/A cg15687855 chr3:44754131 ZNF502 -0.44 -5.27 -0.43 5.84e-7 Depressive symptoms; TGCT trans rs1814175 0.765 rs1721990 chr11:49912154 G/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.36e-13 Height; TGCT cis rs8017423 0.765 rs8017170 chr14:90721849 T/A cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs10946940 0.864 rs13201411 chr6:27498217 G/C cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.6 -0.38 1.04e-5 Systemic lupus erythematosus; TGCT cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg24675658 chr1:53192096 ZYG11B 0.89 11.87 0.73 3.58e-22 Monocyte count; TGCT cis rs6582630 0.519 rs11181294 chr12:38312787 C/T cg26384229 chr12:38710491 ALG10B 0.82 7.18 0.54 5.6e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs9300255 0.602 rs2695476 chr12:123694206 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.1 0.42 1.26e-6 Neutrophil percentage of white cells; TGCT cis rs10984561 0.881 rs7019298 chr9:122251256 A/G cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs4563143 0.514 rs55727361 chr19:29300415 A/T cg14983838 chr19:29218262 NA 0.71 5.19 0.42 8.21e-7 Methadone dose in opioid dependence; TGCT cis rs12950390 0.530 rs16947058 chr17:45825186 A/G cg06532163 chr17:45867833 NA -0.27 -4.65 -0.39 8.33e-6 IgG glycosylation; TGCT cis rs1568889 0.667 rs7123947 chr11:28399908 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 5.57 0.45 1.5e-7 Bipolar disorder; TGCT cis rs10193935 0.681 rs13396880 chr2:42374700 G/T cg27598129 chr2:42591480 NA -0.39 -4.88 -0.4 3.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.850 rs7179388 chr15:44123945 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.01 0.48 1.9e-8 Lung cancer in ever smokers; TGCT trans rs1814175 0.558 rs5025146 chr11:49795724 C/G cg11707556 chr5:10655725 ANKRD33B -0.45 -11.32 -0.71 7.95e-21 Height; TGCT cis rs2153535 0.580 rs3938660 chr6:8443335 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT trans rs17685 0.725 rs6947068 chr7:75662056 T/C cg19862616 chr7:65841803 NCRNA00174 -0.5 -8.42 -0.6 7.75e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7772486 0.790 rs9390365 chr6:146235626 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9911578 0.835 rs1476596 chr17:56485358 C/T cg12560992 chr17:57184187 TRIM37 0.78 9.1 0.63 1.88e-15 Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs875971 0.825 rs10281499 chr7:66048966 A/G cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs4710191 0.510 rs2180713 chr6:167615010 G/A cg07560741 chr6:167734054 NA 0.28 5.66 0.45 1.01e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs34891900 0.507 rs2535679 chr22:18202850 A/G cg19898043 chr22:18121309 BCL2L13 0.55 4.74 0.39 5.77e-6 Sum neutrophil eosinophil counts; TGCT trans rs2688608 0.592 rs10762563 chr10:75524802 C/A cg13918328 chr10:52500089 ASAH2B 0.68 6.83 0.52 3.38e-10 Inflammatory bowel disease; TGCT cis rs8180040 0.620 rs11917361 chr3:47070497 G/T cg27129171 chr3:47204927 SETD2 -0.73 -9.16 -0.64 1.38e-15 Colorectal cancer; TGCT cis rs1843834 0.721 rs6715655 chr2:225582284 C/T cg22455342 chr2:225449267 CUL3 -0.59 -5.54 -0.45 1.77e-7 IgE levels in asthmatics (D.p. specific); TGCT cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg07138768 chr7:917805 C7orf20 0.37 4.5 0.37 1.56e-5 Perceived unattractiveness to mosquitoes; TGCT cis rs6570726 0.791 rs10872577 chr6:145900560 G/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4654899 0.965 rs4654898 chr1:21376383 T/C cg01072550 chr1:21505969 NA -0.51 -8.27 -0.6 1.76e-13 Superior frontal gyrus grey matter volume; TGCT cis rs2841277 0.616 rs1048257 chr14:105404384 T/C cg21017887 chr14:105400489 NA 0.39 5.52 0.44 1.93e-7 Rheumatoid arthritis; TGCT trans rs3780486 0.522 rs10217770 chr9:33146393 C/A cg20290983 chr6:43655470 MRPS18A 0.76 8.2 0.59 2.63e-13 IgG glycosylation; TGCT cis rs12477438 0.765 rs7607578 chr2:99669771 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs12579753 0.797 rs1922561 chr12:82152640 C/A cg21231944 chr12:82153410 PPFIA2 -0.35 -4.61 -0.38 9.96e-6 Resting heart rate; TGCT cis rs7666738 0.830 rs6819177 chr4:99040907 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 1.000 rs28595532 chr4:119716950 A/C cg14228332 chr4:119757509 SEC24D 0.94 5.55 0.45 1.67e-7 Cannabis dependence symptom count; TGCT cis rs7172809 0.599 rs17471480 chr15:77755550 A/G cg22256960 chr15:77711686 NA 0.52 5.0 0.41 1.93e-6 Glucose homeostasis traits; TGCT cis rs3015497 0.789 rs3015496 chr14:51114051 T/C cg04730355 chr14:51134070 SAV1 -0.68 -6.57 -0.51 1.26e-9 Mean platelet volume; TGCT cis rs6988636 0.901 rs16898076 chr8:124187721 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs3096299 0.967 rs2965932 chr16:89477051 C/T cg02187348 chr16:89574699 SPG7 -0.47 -4.54 -0.38 1.32e-5 Multiple myeloma (IgH translocation); TGCT cis rs926938 0.527 rs360594 chr1:115472401 G/A cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs7267979 1.000 rs4813563 chr20:25365340 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10791097 0.547 rs12365680 chr11:130749059 C/T cg12179176 chr11:130786555 SNX19 0.86 10.85 0.7 1.1e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2820315 0.867 rs2819349 chr1:201885026 C/T cg12730843 chr1:201915899 LMOD1 -0.27 -4.86 -0.4 3.46e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs9611565 0.559 rs5751160 chr22:42175695 A/G cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs1395 0.744 rs11126934 chr2:27476613 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs10992471 0.564 rs10491804 chr9:95487407 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -4.56 -0.38 1.21e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1670533 1.000 rs633556 chr4:1092405 A/G cg20887711 chr4:1340912 KIAA1530 0.65 5.12 0.42 1.12e-6 Recombination rate (females); TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg00024416 chr22:24240387 NA -0.28 -5.41 -0.44 3.16e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2204008 0.713 rs2320522 chr12:38251438 C/T cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs394563 0.775 rs448420 chr6:149785802 T/C cg03678062 chr6:149772716 ZC3H12D -0.36 -4.45 -0.37 1.87e-5 Dupuytren's disease; TGCT cis rs737008 0.959 rs11865598 chr16:11403432 T/C cg00044050 chr16:11439710 C16orf75 0.79 8.37 0.6 1.05e-13 Obesity-related traits; TGCT cis rs11969893 0.850 rs3734351 chr6:101307131 C/T cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs7954584 0.567 rs1720033 chr12:122384344 C/T cg13699009 chr12:122356056 WDR66 -0.29 -5.95 -0.47 2.6e-8 Mean corpuscular volume; TGCT cis rs789859 0.965 rs789858 chr3:194405966 C/T cg21106136 chr3:194405973 FAM43A -0.35 -5.06 -0.41 1.46e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs763014 0.966 rs12935215 chr16:670605 T/C cg09263875 chr16:632152 PIGQ 0.31 6.91 0.53 2.25e-10 Height; TGCT cis rs826838 1.000 rs10880914 chr12:38720543 C/T cg26384229 chr12:38710491 ALG10B 1.1 11.12 0.71 2.32e-20 Heart rate; TGCT cis rs7909074 1.000 rs7079573 chr10:45400406 G/A cg05187965 chr10:45406764 TMEM72 -0.24 -5.02 -0.41 1.73e-6 Mean corpuscular volume; TGCT cis rs4285028 0.747 rs10049060 chr3:121358448 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.92 7.3 0.55 3.03e-11 Multiple sclerosis; TGCT cis rs9299 0.778 rs11079830 chr17:46682630 A/G cg25032089 chr17:46643351 HOXB3 0.45 5.74 0.46 6.97e-8 Obesity; TGCT cis rs202629 1 rs202629 chr22:41849975 C/T cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Cannabis dependence symptom count; TGCT cis rs17076896 0.786 rs7325441 chr13:19934252 A/G cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7677751 0.806 rs6554163 chr4:55102559 A/T cg17187183 chr4:55093834 PDGFRA 0.56 7.19 0.54 5.34e-11 Corneal astigmatism; TGCT cis rs7043114 0.563 rs10820990 chr9:95323297 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.54 5.37 0.43 3.78e-7 Height; TGCT cis rs5167 0.743 rs8111069 chr19:45483438 A/C cg13119609 chr19:45449297 APOC2 0.23 4.73 0.39 5.98e-6 Blood protein levels; TGCT cis rs10493389 0.591 rs10889587 chr1:66281473 T/C cg08716655 chr1:66257732 PDE4B -0.45 -4.62 -0.38 9.34e-6 Echocardiographic traits; TGCT cis rs4319547 0.695 rs113841747 chr12:122886088 G/T cg05707623 chr12:122985044 ZCCHC8 0.62 4.88 0.4 3.17e-6 Body mass index; TGCT cis rs28595532 0.920 rs115372254 chr4:119771735 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs9660180 0.836 rs72634845 chr1:1704899 G/A cg20999797 chr1:1681921 NA 0.18 4.78 0.39 4.93e-6 Body mass index; TGCT cis rs8180040 0.903 rs2276854 chr3:47276968 C/T cg27129171 chr3:47204927 SETD2 0.71 8.58 0.61 3.22e-14 Colorectal cancer; TGCT cis rs3796352 1.000 rs2336541 chr3:52974630 G/C cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7659604 0.605 rs67772833 chr4:122723106 G/A cg20573242 chr4:122745356 CCNA2 0.57 5.25 0.43 6.28e-7 Type 2 diabetes; TGCT cis rs200810 0.634 rs62422095 chr6:97991825 T/A cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.68 -4.65 -0.39 8.37e-6 Body mass index; TGCT cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg03396347 chr1:1875803 NA 0.37 6.79 0.52 4.1e-10 Body mass index; TGCT cis rs13223928 0.536 rs12700594 chr7:3156701 G/A cg19214707 chr7:3157722 NA 0.46 6.97 0.53 1.64e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs79149102 0.579 rs28394281 chr15:75326754 C/G cg09165964 chr15:75287851 SCAMP5 -1.07 -5.81 -0.46 4.93e-8 Lung cancer; TGCT cis rs2229238 0.780 rs61698846 chr1:154504854 C/T cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs6089584 1.000 rs6089584 chr20:60564086 G/C cg16423285 chr20:60520624 NA -0.52 -5.62 -0.45 1.18e-7 Body mass index; TGCT trans rs208520 1.000 rs9453671 chr6:66991208 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.79 7.05 0.53 1.12e-10 Exhaled nitric oxide output; TGCT cis rs1505368 0.781 rs4673664 chr2:213277649 T/C cg20637307 chr2:213403960 ERBB4 0.48 4.67 0.39 7.82e-6 Symmetrical dimethylarginine levels; TGCT cis rs492146 0.765 rs316141 chr6:52846158 A/G cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs7267979 0.586 rs6050429 chr20:25183058 G/A cg16686733 chr20:25566563 NINL 0.53 5.43 0.44 2.9e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs473651 0.716 rs548179 chr2:239320505 G/A cg08773314 chr2:239334832 ASB1 0.48 8.01 0.58 7.01e-13 Multiple system atrophy; TGCT cis rs11105298 0.891 rs12369685 chr12:89928905 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.08 -0.42 1.35e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs769267 0.896 rs2074298 chr19:19377716 C/G cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs4253772 0.530 rs9615955 chr22:46743931 A/G cg24881330 chr22:46731750 TRMU 1.09 5.61 0.45 1.28e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs8072100 0.935 rs4793978 chr17:45698175 G/A cg08085267 chr17:45401833 C17orf57 0.43 4.64 0.38 8.8e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs617219 0.591 rs1840805 chr5:78565563 T/A cg09550809 chr5:78407562 BHMT -0.38 -5.28 -0.43 5.63e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9807989 0.507 rs6755905 chr2:103048207 C/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs826838 0.967 rs1684411 chr12:39128494 C/T cg26384229 chr12:38710491 ALG10B -0.83 -7.31 -0.55 2.88e-11 Heart rate; TGCT cis rs72949976 0.584 rs4673729 chr2:214023810 A/G cg08319019 chr2:214017104 IKZF2 0.84 8.38 0.6 9.58e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs7772486 0.686 rs9376956 chr6:145949844 T/C cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2299587 0.623 rs12718384 chr8:17781112 T/C cg01800426 chr8:17659068 MTUS1 -0.65 -5.61 -0.45 1.26e-7 Economic and political preferences; TGCT cis rs3806843 0.608 rs155364 chr5:140346468 T/A cg07102913 chr5:140593443 PCDHB13 -0.48 -4.81 -0.4 4.33e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7000551 0.532 rs55726237 chr8:22252985 C/T cg12081754 chr8:22256438 SLC39A14 0.35 4.99 0.41 1.98e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6912958 0.547 rs451089 chr6:88041859 A/G cg10393598 chr6:87862264 NA -0.31 -4.5 -0.37 1.55e-5 Monocyte percentage of white cells; TGCT cis rs2235642 1.000 rs2235642 chr16:1584866 T/C cg07341220 chr16:1583899 IFT140;TMEM204 -0.29 -4.64 -0.38 8.66e-6 Coronary artery disease; TGCT cis rs7959452 0.605 rs12819406 chr12:69696400 G/T cg14784868 chr12:69753453 YEATS4 0.68 6.95 0.53 1.81e-10 Blood protein levels; TGCT cis rs9913156 0.793 rs7210953 chr17:4608870 C/T cg00122941 chr17:4613640 ARRB2 0.88 7.63 0.57 5.46e-12 Lymphocyte counts; TGCT cis rs8177253 1.000 rs8177247 chr3:133479499 T/G cg08048268 chr3:133502702 NA -0.66 -9.83 -0.66 3.36e-17 Iron status biomarkers; TGCT cis rs1577917 0.959 rs34258068 chr6:86679449 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.48 -0.44 2.27e-7 Response to antipsychotic treatment; TGCT cis rs12477438 0.765 rs9710648 chr2:99673129 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs11785400 0.762 rs4401833 chr8:143739731 A/T cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs13217239 0.646 rs6937880 chr6:27000236 C/T cg26531700 chr6:26746687 NA 0.68 6.86 0.52 2.83e-10 Schizophrenia; TGCT cis rs55882075 0.730 rs10794700 chr5:179148335 C/G cg14593053 chr5:179126677 CANX 0.48 5.4 0.44 3.23e-7 Monocyte percentage of white cells; TGCT cis rs9394169 0.818 rs1547671 chr6:33777260 C/T cg13859433 chr6:33739653 LEMD2 -0.28 -4.99 -0.41 2.02e-6 Essential tremor; TGCT cis rs62244186 0.627 rs12386385 chr3:44457540 A/G cg04389838 chr3:44770851 ZNF501 -0.4 -5.3 -0.43 5.22e-7 Depressive symptoms; TGCT cis rs1375194 0.606 rs13393407 chr2:33818198 C/T cg04131969 chr2:33951647 MYADML -0.53 -4.51 -0.38 1.49e-5 Response to antidepressants in depression; TGCT cis rs2458413 0.521 rs2458427 chr8:105339594 G/T cg23108931 chr8:105342351 NA -0.36 -6.39 -0.5 3.05e-9 Paget's disease; TGCT cis rs5769765 0.955 rs2295406 chr22:50260169 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.71 0.72 8.52e-22 Schizophrenia; TGCT cis rs4699052 0.590 rs1156669 chr4:104288204 A/C cg16532752 chr4:104119610 CENPE -0.5 -4.75 -0.39 5.48e-6 Testicular germ cell tumor; TGCT cis rs4665809 1.000 rs4665305 chr2:26313524 C/T cg25036284 chr2:26402008 FAM59B -0.56 -4.88 -0.4 3.2e-6 Gut microbiome composition (summer); TGCT cis rs7746199 0.736 rs6904596 chr6:27491299 G/A cg26587870 chr6:27730563 NA -0.48 -4.82 -0.4 4.1e-6 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs3087591 0.762 rs7502029 chr17:29590791 T/A cg24425628 chr17:29625626 OMG;NF1 0.46 6.82 0.52 3.53e-10 Hip circumference; TGCT cis rs739496 0.843 rs619010 chr12:111974823 A/G cg10833066 chr12:111807467 FAM109A 0.37 5.41 0.44 3.1e-7 Platelet count; TGCT cis rs290268 1.000 rs290268 chr9:93552450 A/G cg02608019 chr9:93564028 SYK 0.48 4.82 0.4 4.19e-6 Platelet count; TGCT cis rs514406 0.505 rs146750 chr1:53183447 C/G cg25767906 chr1:53392781 SCP2 -0.47 -5.41 -0.44 3.17e-7 Monocyte count; TGCT cis rs13102973 0.931 rs12499856 chr4:135868573 C/T cg14419869 chr4:135874104 NA 0.24 4.46 0.37 1.83e-5 Subjective well-being; TGCT cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg25767906 chr1:53392781 SCP2 -0.52 -6.02 -0.48 1.82e-8 Monocyte count; TGCT cis rs2249625 0.545 rs2496487 chr6:72875226 G/C cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs11711311 1.000 rs12695295 chr3:113474866 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs9902453 0.740 rs2729446 chr17:28102499 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs6490294 0.748 rs6489820 chr12:112328503 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Mean platelet volume; TGCT cis rs7523273 0.565 rs2488248 chr1:207899682 C/T cg22525895 chr1:207977042 MIR29B2 -0.33 -5.31 -0.43 4.83e-7 Schizophrenia; TGCT cis rs9611565 0.765 rs132906 chr22:41799767 G/C cg06634786 chr22:41940651 POLR3H 0.65 6.2 0.49 7.8e-9 Vitiligo; TGCT cis rs2153535 0.601 rs9505472 chr6:8538765 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs910316 0.737 rs398896 chr14:75482827 C/A cg08847533 chr14:75593920 NEK9 -0.87 -9.09 -0.63 1.95e-15 Height; TGCT cis rs10465746 0.901 rs17475760 chr1:84398435 A/T cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs9467711 0.606 rs12174602 chr6:26372827 C/T cg10795676 chr6:26370623 BTN3A2 -0.51 -5.27 -0.43 5.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4689388 0.610 rs4328980 chr4:6281756 A/G cg25554036 chr4:6271136 WFS1 0.53 6.84 0.52 3.27e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6671200 1.000 rs60929805 chr1:95646386 C/T cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs904251 0.523 rs9369005 chr6:37483109 A/G cg01843034 chr6:37503916 NA -0.53 -7.14 -0.54 7.06e-11 Cognitive performance; TGCT cis rs3809566 1.000 rs10851721 chr15:63332383 T/C cg05507819 chr15:63340323 TPM1 0.48 4.52 0.38 1.4e-5 Platelet count; TGCT cis rs2404602 0.692 rs35170561 chr15:77130695 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.21e-6 Blood metabolite levels; TGCT cis rs9972944 0.729 rs10083877 chr17:63773623 T/C cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs7666738 0.546 rs1456207 chr4:98676911 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.73 0.39 5.89e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9443189 0.615 rs6453829 chr6:76268509 C/T cg01950844 chr6:76311363 SENP6 0.95 5.82 0.46 4.69e-8 Prostate cancer; TGCT cis rs10193935 1.000 rs10210866 chr2:42387879 A/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9357506 0.967 rs9381443 chr6:46316567 A/G cg21115430 chr6:46460003 NA -0.25 -4.8 -0.4 4.49e-6 Body mass index; TGCT cis rs711245 0.572 rs3821150 chr2:36795233 G/A cg15105969 chr2:36825350 FEZ2 0.56 4.76 0.39 5.3e-6 Height; TGCT cis rs6546537 0.910 rs10779953 chr2:69886757 A/G cg10773587 chr2:69614142 GFPT1 -0.72 -6.53 -0.51 1.5e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs11621121 0.556 rs2127870 chr14:65796846 C/G cg04536575 chr14:65016802 C14orf50 -0.64 -4.46 -0.37 1.84e-5 N-glycan levels; TGCT cis rs1218582 0.710 rs4845687 chr1:154878911 A/G cg09359103 chr1:154839909 KCNN3 -0.64 -11.6 -0.72 1.58e-21 Prostate cancer; TGCT cis rs7605378 0.528 rs7592587 chr2:200786516 C/G cg23649088 chr2:200775458 C2orf69 0.48 10.23 0.68 3.47e-18 Osteoporosis; TGCT cis rs3008870 0.755 rs2815381 chr1:67514591 G/A cg02640540 chr1:67518911 SLC35D1 0.69 6.17 0.48 8.93e-9 Lymphocyte percentage of white cells; TGCT cis rs986417 1.000 rs1951114 chr14:60922005 C/G cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs172166 0.694 rs203892 chr6:28067196 T/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.79 0.39 4.75e-6 Cardiac Troponin-T levels; TGCT cis rs9534288 0.619 rs9526143 chr13:46675991 C/T cg15192986 chr13:46630673 CPB2 -0.5 -6.04 -0.48 1.65e-8 Blood protein levels; TGCT cis rs597539 0.521 rs7943745 chr11:68605828 A/G cg06112835 chr11:68658793 MRPL21 -0.33 -5.58 -0.45 1.47e-7 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs921968 0.541 rs485975 chr2:219374250 C/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6840360 0.642 rs2709833 chr4:152377622 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs2964802 0.505 rs11133627 chr5:10830474 T/G cg14521931 chr5:10832172 NA -0.26 -4.46 -0.37 1.78e-5 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs3733585 0.699 rs11724510 chr4:9958583 C/T cg11266682 chr4:10021025 SLC2A9 -0.57 -7.47 -0.56 1.23e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs17076896 0.786 rs17080342 chr13:19926967 C/T cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs9583531 0.660 rs61971611 chr13:111335319 C/T cg15747390 chr13:111297551 CARS2 0.88 5.97 0.47 2.32e-8 Coronary artery disease; TGCT cis rs2251381 0.750 rs2251087 chr21:30527999 C/T cg24692254 chr21:30365293 RNF160 0.74 7.03 0.53 1.23e-10 Selective IgA deficiency; TGCT cis rs854765 0.583 rs4925123 chr17:17784374 A/G cg09796270 chr17:17721594 SREBF1 -0.27 -5.63 -0.45 1.16e-7 Total body bone mineral density; TGCT cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg01411255 chr17:61851458 DDX42;CCDC47 -0.72 -7.13 -0.54 7.39e-11 Prudent dietary pattern; TGCT cis rs2153535 0.580 rs1577472 chr6:8486215 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs13326165 0.760 rs35133416 chr3:52359040 C/T cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7586879 1.000 rs10207698 chr2:25117672 C/T cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs868036 0.681 rs4776981 chr15:68109474 G/A cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs12477438 0.520 rs2632277 chr2:99778985 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.57 0.77 2.9e-26 Chronic sinus infection; TGCT cis rs9486719 0.843 rs2103539 chr6:96844342 T/A cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs7605378 0.528 rs7592587 chr2:200786516 C/G cg17644776 chr2:200775616 C2orf69 0.33 7.36 0.55 2.18e-11 Osteoporosis; TGCT cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg26119090 chr2:26468346 HADHA;HADHB 0.91 6.41 0.5 2.79e-9 Gut microbiome composition (summer); TGCT cis rs1949733 0.523 rs16842557 chr4:8543985 C/T cg13073564 chr4:8508604 NA 0.5 4.94 0.41 2.46e-6 Response to antineoplastic agents; TGCT cis rs11696501 0.688 rs6073834 chr20:44279989 C/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs17376456 0.778 rs10440717 chr5:93424852 C/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs7954584 0.531 rs1154514 chr12:122374888 C/T cg21016266 chr12:122356598 WDR66 0.53 6.58 0.51 1.19e-9 Mean corpuscular volume; TGCT cis rs9811920 0.638 rs793440 chr3:99643176 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.92 -0.53 2.1e-10 Axial length; TGCT cis rs6074578 0.679 rs11087789 chr20:139173 A/G cg16931068 chr20:139680 DEFB127 0.27 4.54 0.38 1.33e-5 Hirschsprung disease; TGCT cis rs10858047 0.883 rs6537843 chr1:115210578 C/A cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs548987 0.529 rs9467618 chr6:25824809 C/T cg12310025 chr6:25882481 NA -0.57 -4.61 -0.38 9.67e-6 Homocysteine levels; TGCT trans rs877282 0.733 rs11253342 chr10:765072 A/G cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs2204008 0.777 rs114096617 chr12:38342557 A/C cg13010199 chr12:38710504 ALG10B 0.59 4.63 0.38 9.17e-6 Bladder cancer; TGCT cis rs4253772 0.626 rs9615960 chr22:46752307 G/A cg24881330 chr22:46731750 TRMU 0.94 4.43 0.37 2.01e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg23205692 chr1:25664452 TMEM50A 0.48 5.07 0.41 1.42e-6 Plateletcrit;Mean corpuscular volume; TGCT cis rs7615952 0.800 rs11914298 chr3:125643772 G/A cg05084668 chr3:125655381 ALG1L -0.76 -6.17 -0.48 8.82e-9 Blood pressure (smoking interaction); TGCT cis rs933688 0.532 rs28693622 chr5:90538722 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.54 -4.82 -0.4 4.09e-6 Smoking behavior; TGCT cis rs2197308 0.765 rs12230545 chr12:37927114 C/T cg26384229 chr12:38710491 ALG10B -0.71 -6.31 -0.49 4.42e-9 Morning vs. evening chronotype; TGCT cis rs3806843 0.766 rs6848 chr5:140086062 A/T cg19875535 chr5:140030758 IK -0.35 -6.02 -0.48 1.85e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs1218582 0.651 rs4845396 chr1:154828409 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.55 5.15 0.42 1.01e-6 Prostate cancer; TGCT cis rs6684514 1.000 rs3806408 chr1:156252137 C/A cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9296092 0.517 rs11751684 chr6:33528739 G/T cg13560919 chr6:33536144 NA -0.23 -4.95 -0.41 2.4e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9303401 0.659 rs34351230 chr17:56782555 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs8077889 0.917 rs60335331 chr17:41907509 A/G cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs4727027 0.804 rs13231262 chr7:148886058 C/T cg23583168 chr7:148888333 NA -0.77 -9.95 -0.67 1.63e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg10802521 chr3:52805072 NEK4 -0.73 -9.14 -0.63 1.51e-15 Bipolar disorder; TGCT trans rs2727020 0.704 rs4144700 chr11:49370834 C/A cg03929089 chr4:120376271 NA -0.74 -8.68 -0.61 1.87e-14 Coronary artery disease; TGCT cis rs76419734 0.558 rs10030620 chr4:106574536 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.71 4.56 0.38 1.22e-5 Post bronchodilator FEV1; TGCT cis rs1784581 0.588 rs7752870 chr6:162422510 T/C cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs826838 0.900 rs9739128 chr12:38948960 A/T cg13010199 chr12:38710504 ALG10B 0.8 6.74 0.52 5.43e-10 Heart rate; TGCT cis rs700651 0.754 rs1518367 chr2:198807015 T/A cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Intracranial aneurysm; TGCT cis rs1799949 0.965 rs799910 chr17:41279561 G/C cg05368731 chr17:41323189 NBR1 1.02 11.3 0.71 8.52e-21 Menopause (age at onset); TGCT cis rs2841277 0.616 rs1048257 chr14:105404384 T/C cg19901468 chr14:105411992 AHNAK2 -0.28 -5.86 -0.47 3.96e-8 Rheumatoid arthritis; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg00024416 chr22:24240387 NA -0.25 -4.84 -0.4 3.86e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3806843 0.932 rs2563256 chr5:140141779 G/T cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9457247 1.000 rs408080 chr6:167392522 T/C cg23791538 chr6:167370224 RNASET2 -0.53 -5.18 -0.42 8.72e-7 Crohn's disease; TGCT cis rs11711311 0.955 rs9881563 chr3:113414031 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.79 7.05 0.53 1.11e-10 IgG glycosylation; TGCT cis rs7772486 0.686 rs1045820 chr6:145947080 C/T cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 0.727 rs7521344 chr1:76318325 C/T cg10523679 chr1:76189770 ACADM -0.67 -6.36 -0.5 3.5e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9486719 1.000 rs2472887 chr6:96865437 A/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs80033912 0.640 rs6785832 chr3:49224316 C/T cg07690219 chr3:49449608 TCTA;RHOA -0.47 -4.51 -0.38 1.49e-5 Intelligence (multi-trait analysis); TGCT cis rs25422 0.938 rs114309775 chr6:118838782 G/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Renal cell carcinoma; TGCT cis rs17376456 0.877 rs10070390 chr5:93452345 G/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs76878669 0.561 rs11227465 chr11:66115879 T/A cg18002602 chr11:66138449 SLC29A2 -0.53 -6.3 -0.49 4.69e-9 Educational attainment (years of education); TGCT cis rs2469997 1.000 rs2470016 chr8:120361220 T/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs9467711 0.606 rs34878490 chr6:26370572 C/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs73001065 0.591 rs2285626 chr19:19467545 C/T cg03709012 chr19:19516395 GATAD2A 0.85 5.39 0.44 3.4e-7 LDL cholesterol; TGCT cis rs2066819 1.000 rs41392645 chr12:56696742 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs9303401 0.659 rs56162835 chr17:56687315 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs11098499 0.604 rs2389882 chr4:120566733 A/C cg09307838 chr4:120376055 NA 0.64 6.05 0.48 1.57e-8 Corneal astigmatism; TGCT cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6598955 0.543 rs112752634 chr1:26534217 G/A cg04990556 chr1:26633338 UBXN11 0.81 7.32 0.55 2.76e-11 Obesity-related traits; TGCT cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg06238570 chr21:40685208 BRWD1 0.58 5.2 0.42 7.95e-7 Cognitive function; TGCT cis rs2016266 0.752 rs10783562 chr12:53657467 G/A cg16917193 chr12:54089295 NA 0.65 4.82 0.4 4.19e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs4660306 0.961 rs2152077 chr1:45986670 G/T cg15605315 chr1:45957053 TESK2 0.47 4.47 0.37 1.72e-5 Homocysteine levels; TGCT cis rs11167764 0.945 rs7720832 chr5:141473097 T/G cg23435118 chr5:141488016 NDFIP1 -0.28 -4.58 -0.38 1.1e-5 Crohn's disease; TGCT cis rs1348850 0.914 rs11893448 chr2:178280013 T/C cg22681709 chr2:178499509 PDE11A -0.34 -4.47 -0.37 1.74e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs4148883 0.675 rs28762430 chr4:100119257 C/A cg12011299 chr4:100065546 ADH4 0.39 5.88 0.47 3.53e-8 Alcohol dependence; TGCT cis rs6938 0.618 rs12911254 chr15:75166335 G/A cg09165964 chr15:75287851 SCAMP5 0.58 5.33 0.43 4.45e-7 Breast cancer; TGCT cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg03303774 chr4:1407052 NA 0.29 4.65 0.39 8.26e-6 Obesity-related traits; TGCT cis rs2762353 0.902 rs1165199 chr6:25809087 C/T cg03264133 chr6:25882463 NA -0.51 -5.36 -0.43 3.84e-7 Blood metabolite levels; TGCT cis rs11190604 1.000 rs11190596 chr10:102293238 C/G cg16342193 chr10:102329863 NA -0.46 -5.86 -0.47 3.89e-8 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6582630 0.502 rs12815350 chr12:38439921 A/T cg13010199 chr12:38710504 ALG10B 0.56 4.44 0.37 2e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs6951245 1.000 rs79443843 chr7:1075245 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.17e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9549367 0.773 rs9549717 chr13:113908826 A/G cg00898013 chr13:113819073 PROZ -0.43 -5.55 -0.45 1.68e-7 Platelet distribution width; TGCT trans rs7726839 0.526 rs11960159 chr5:568685 C/T cg11887960 chr12:57824829 NA 1.03 7.93 0.58 1.11e-12 Obesity-related traits; TGCT cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg07424592 chr7:64974309 NA 1.33 8.82 0.62 8.94e-15 Diabetic kidney disease; TGCT cis rs9611519 0.964 rs5995992 chr22:41487218 T/C cg13695892 chr22:41940480 POLR3H -0.5 -4.53 -0.38 1.39e-5 Neuroticism; TGCT cis rs614226 1.000 rs1614223 chr12:120964043 T/C cg01236616 chr12:121019343 POP5 1.26 13.2 0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT trans rs17685 0.753 rs1637039 chr7:75693009 C/T cg19862616 chr7:65841803 NCRNA00174 0.51 8.73 0.62 1.42e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs35306767 0.761 rs11253560 chr10:1047226 T/G cg26597838 chr10:835615 NA 0.6 6.63 0.51 9.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs2153535 0.580 rs7743418 chr6:8438128 A/C cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs9911578 0.967 rs2611781 chr17:56703124 C/G cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs9291683 0.546 rs13139055 chr4:10038924 G/T cg00071950 chr4:10020882 SLC2A9 0.6 6.89 0.53 2.49e-10 Bone mineral density; TGCT cis rs7246657 0.943 rs12709813 chr19:37844983 G/A cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.3e-7 Coronary artery calcification; TGCT cis rs6089829 0.962 rs6062777 chr20:61663748 G/A cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs1561288 0.553 rs12233134 chr2:25329016 C/T cg15423357 chr2:25149977 NA -0.5 -4.51 -0.38 1.49e-5 Body mass index; TGCT cis rs4268898 0.697 rs10445892 chr2:24406958 T/C cg02683114 chr2:24398427 C2orf84 0.19 4.76 0.39 5.37e-6 Asthma; TGCT cis rs739496 0.563 rs61547643 chr12:112266624 G/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7267979 1.000 rs2257420 chr20:25275890 C/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7225537 0.507 rs2292530 chr17:17075318 A/G cg26176665 chr17:16994978 MPRIP 0.23 5.35 0.43 4.18e-7 Mean platelet volume; TGCT cis rs752590 0.650 rs6751201 chr2:113952699 C/G cg27425262 chr2:113953981 PSD4;LOC440839 -0.39 -4.62 -0.38 9.44e-6 Mucinous ovarian carcinoma; TGCT cis rs875971 0.522 rs781144 chr7:65440344 C/G cg00343986 chr7:65444356 GUSB 0.25 5.63 0.45 1.15e-7 Aortic root size; TGCT cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg16049864 chr8:95962084 TP53INP1 -0.71 -9.68 -0.66 7.71e-17 Type 2 diabetes; TGCT cis rs7666738 0.830 rs10014284 chr4:98681951 G/C cg17366294 chr4:99064904 C4orf37 0.62 6.4 0.5 2.94e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.606 rs3846447 chr4:99099907 G/A cg18180107 chr4:99064573 C4orf37 0.51 4.58 0.38 1.09e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs3749237 0.964 rs35210174 chr3:49812606 C/T cg03060546 chr3:49711283 APEH 0.72 7.38 0.55 2.02e-11 Resting heart rate; TGCT trans rs877282 0.797 rs7079164 chr10:756363 A/G cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs595982 0.661 rs657008 chr19:49373632 A/G cg21252483 chr19:49399788 TULP2 -0.26 -4.57 -0.38 1.18e-5 Red cell distribution width; TGCT cis rs67311347 0.640 rs7434088 chr3:40297288 T/C cg13683864 chr3:40499215 RPL14 -0.74 -6.79 -0.52 4.2e-10 Renal cell carcinoma; TGCT trans rs6089829 0.962 rs4809462 chr20:61661560 A/G cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1577917 0.696 rs10806334 chr6:86439329 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -5.16 -0.42 9.69e-7 Response to antipsychotic treatment; TGCT cis rs10791097 0.967 rs10791099 chr11:130718813 G/C cg05962950 chr11:130786565 SNX19 0.75 8.13 0.59 3.73e-13 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs17471911 0.643 rs11189947 chr10:100797203 A/G cg03484267 chr2:207988651 KLF7 -0.52 -6.79 -0.52 4.17e-10 Neuroticism; TGCT cis rs3733585 0.673 rs4519796 chr4:9955936 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg06212747 chr3:49208901 KLHDC8B -0.68 -6.37 -0.5 3.34e-9 Menarche (age at onset); TGCT cis rs7267979 0.932 rs6132848 chr20:25561645 C/T cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62103177 0.565 rs473119 chr18:77849459 T/G cg07235805 chr18:78004237 PARD6G -0.52 -5.04 -0.41 1.57e-6 Opioid sensitivity; TGCT cis rs9372498 0.536 rs9489450 chr6:118904385 G/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.04 -0.41 1.59e-6 Diastolic blood pressure; TGCT cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg13393036 chr8:95962371 TP53INP1 0.56 6.85 0.52 3.02e-10 Type 2 diabetes; TGCT cis rs12477438 0.501 rs12995473 chr2:99764884 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs9638182 0.673 rs79862839 chr7:72921609 T/C cg14087351 chr7:73037990 MLXIPL -0.61 -4.81 -0.4 4.34e-6 Triglycerides; TGCT cis rs7592578 0.766 rs12472081 chr2:191398545 G/A cg11845111 chr2:191398756 TMEM194B -0.42 -4.48 -0.37 1.69e-5 Diastolic blood pressure; TGCT cis rs28595532 0.920 rs10025640 chr4:119787451 G/A cg00700008 chr4:120138107 USP53 0.49 4.48 0.37 1.71e-5 Cannabis dependence symptom count; TGCT cis rs6940638 1.000 rs12215773 chr6:27039233 T/C cg16898833 chr6:26189333 HIST1H4D 0.76 5.61 0.45 1.27e-7 Intelligence (multi-trait analysis); TGCT cis rs11031096 0.803 rs10082689 chr11:4172575 A/G cg18678763 chr11:4115507 RRM1 0.39 5.28 0.43 5.52e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2295359 1.000 rs963427 chr1:67609347 A/G cg12940439 chr1:67600707 NA 0.58 6.21 0.49 7.19e-9 Psoriasis; TGCT cis rs1005277 0.540 rs2474598 chr10:38430296 C/T cg25427524 chr10:38739819 LOC399744 0.39 7.85 0.58 1.67e-12 Extrinsic epigenetic age acceleration; TGCT cis rs2115630 0.967 rs7171167 chr15:85239123 A/T cg24513567 chr15:85260248 SEC11A -0.35 -4.57 -0.38 1.15e-5 P wave terminal force; TGCT cis rs7617773 0.817 rs13094727 chr3:48323489 G/A cg11946769 chr3:48343235 NME6 0.76 6.57 0.51 1.23e-9 Coronary artery disease; TGCT trans rs12339966 0.615 rs73642474 chr9:11368518 G/A cg03488587 chr11:64876988 C11orf2 0.29 6.8 0.52 4.04e-10 Systolic blood pressure; TGCT cis rs5757676 1.000 rs5757676 chr22:39841700 T/C cg02038168 chr22:39784481 NA -0.76 -5.2 -0.42 7.93e-7 IgG glycosylation; TGCT cis rs12893668 0.572 rs12590968 chr14:104136633 G/C cg26031613 chr14:104095156 KLC1 -0.59 -5.08 -0.42 1.34e-6 Reticulocyte count; TGCT cis rs2239547 0.522 rs6770957 chr3:52995416 T/C cg11645453 chr3:52864694 ITIH4 0.32 5.27 0.43 5.93e-7 Schizophrenia; TGCT cis rs9942416 0.660 rs61173369 chr5:74997995 A/G cg02573091 chr5:74908125 NA 0.38 4.51 0.38 1.47e-5 Age-related disease endophenotypes; TGCT cis rs17331151 0.573 rs13080929 chr3:52885112 A/C cg11137980 chr3:52469226 SEMA3G 0.29 5.12 0.42 1.13e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs17384381 1.000 rs12758237 chr1:85870783 G/A cg16011679 chr1:85725395 C1orf52 0.78 6.1 0.48 1.27e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs858239 0.508 rs7805071 chr7:23190212 C/T cg05602783 chr7:23145260 KLHL7 -0.68 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg01802117 chr1:53393560 SCP2 -0.39 -4.55 -0.38 1.27e-5 Monocyte count; TGCT cis rs61867294 0.553 rs7090254 chr10:106730404 C/T cg08000847 chr10:105880925 C10orf78 0.48 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs7572733 0.515 rs6724526 chr2:198858401 A/G cg00792783 chr2:198669748 PLCL1 0.57 5.1 0.42 1.24e-6 Dermatomyositis; TGCT cis rs6988636 1.000 rs13261066 chr8:124190276 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs7937682 0.855 rs7934922 chr11:111500026 T/C cg09085632 chr11:111637200 PPP2R1B -1.11 -11.7 -0.72 9.24e-22 Primary sclerosing cholangitis; TGCT cis rs4689388 0.926 rs5018648 chr4:6292818 C/G cg00701064 chr4:6280414 WFS1 -0.37 -4.73 -0.39 5.98e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9807989 0.507 rs13021177 chr2:103056493 A/G cg03938978 chr2:103052716 IL18RAP 0.26 5.28 0.43 5.56e-7 Asthma; TGCT cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg15320075 chr8:145703422 NA -0.71 -7.16 -0.54 6.3e-11 Age at first birth; TGCT cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg24829409 chr8:58192753 C8orf71 -0.64 -5.31 -0.43 4.89e-7 Developmental language disorder (linguistic errors); TGCT cis rs9902453 0.967 rs11080121 chr17:28528842 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.37 0.5 3.28e-9 Coffee consumption (cups per day); TGCT cis rs910316 0.712 rs175037 chr14:75465038 T/C cg08847533 chr14:75593920 NEK9 -0.84 -9.15 -0.64 1.4e-15 Height; TGCT cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg00738919 chr7:1100172 C7orf50 0.47 4.6 0.38 1.04e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7246657 0.663 rs4803287 chr19:38079435 A/G cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs6952808 0.689 rs58227534 chr7:2046328 A/G cg22963979 chr7:1858916 MAD1L1 -0.47 -7.55 -0.56 8.09e-12 Bipolar disorder and schizophrenia; TGCT cis rs4819052 0.851 rs1006779 chr21:46670752 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.89 0.53 2.53e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11690935 0.921 rs7594711 chr2:172895637 T/G cg13550731 chr2:172543902 DYNC1I2 -1.14 -11.28 -0.71 9.47e-21 Schizophrenia; TGCT cis rs11673344 0.523 rs2562609 chr19:37527157 C/T cg08039142 chr19:36980659 ZNF566 0.51 4.72 0.39 6.16e-6 Obesity-related traits; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg25703541 chr22:24373054 LOC391322 -0.93 -10.97 -0.7 5.66e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs250677 0.522 rs1007400 chr5:148382635 C/T cg18129178 chr5:148520854 ABLIM3 0.36 4.7 0.39 6.92e-6 Breast cancer; TGCT cis rs6500602 0.627 rs3848372 chr16:4587875 C/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.39 6.85 0.52 3e-10 Schizophrenia; TGCT cis rs2639990 0.744 rs640261 chr18:72905808 C/T cg02750262 chr18:72916776 ZADH2 0.88 6.43 0.5 2.49e-9 Vascular endothelial growth factor levels; TGCT cis rs9818758 0.545 rs9853352 chr3:49813258 C/T cg07636037 chr3:49044803 WDR6 1.01 4.93 0.4 2.63e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs11169225 0.906 rs399023 chr12:50338952 A/C cg23855989 chr12:50355821 AQP5 0.41 4.92 0.4 2.74e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs1005224 0.889 rs10132250 chr14:76124380 C/A cg25116370 chr14:76127843 TTLL5;C14orf1 -0.53 -4.8 -0.4 4.48e-6 Large artery stroke; TGCT cis rs7818688 0.654 rs896848 chr8:95981810 G/A cg16049864 chr8:95962084 TP53INP1 0.5 4.52 0.38 1.44e-5 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs13185784 0.667 rs4309929 chr5:179650988 A/C cg04734276 chr5:178882605 NA 0.29 4.51 0.38 1.5e-5 TRAIL levels; TGCT cis rs4891159 0.790 rs1787448 chr18:74113179 T/C cg24786174 chr18:74118243 ZNF516 0.63 9.91 0.66 2.07e-17 Longevity; TGCT cis rs7095607 1.000 rs7094660 chr10:69956912 A/G cg18986048 chr10:69913749 MYPN 0.46 4.93 0.41 2.54e-6 Lung function (FVC); TGCT cis rs11874712 0.965 rs8083998 chr18:43673144 A/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs7659604 1.000 rs34952897 chr4:122664409 C/T cg19748678 chr4:122722346 EXOSC9 0.57 5.54 0.45 1.69e-7 Type 2 diabetes; TGCT cis rs67311347 0.544 rs4974040 chr3:40331059 G/A cg13683864 chr3:40499215 RPL14 -0.78 -7.45 -0.56 1.42e-11 Renal cell carcinoma; TGCT trans rs9951602 0.512 rs7232551 chr18:76650702 G/A cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs7845219 0.544 rs4570121 chr8:95917088 C/T cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg08280861 chr8:58055591 NA 0.55 6.23 0.49 6.59e-9 Developmental language disorder (linguistic errors); TGCT cis rs11122272 0.735 rs2486735 chr1:231521778 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs9902453 1.000 rs4350617 chr17:28423088 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.52 0.51 1.63e-9 Coffee consumption (cups per day); TGCT cis rs6969780 1.000 rs73071550 chr7:27149099 T/C cg04317399 chr7:27170313 HOXA4 0.48 4.46 0.37 1.81e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs16867321 0.853 rs73023563 chr2:181502830 C/T cg23363182 chr2:181467187 NA -0.4 -5.7 -0.46 8.41e-8 Obesity; TGCT trans rs459571 0.796 rs10993894 chr9:136884511 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.76 -8.27 -0.6 1.79e-13 Platelet distribution width; TGCT cis rs688020 1.000 rs688020 chr7:4228553 C/T cg24441899 chr7:4244372 SDK1 0.41 5.3 0.43 5.21e-7 Liver fibrosis in pediatric non-alcoholic fatty acid liver disease; TGCT cis rs7267979 1.000 rs6050629 chr20:25430680 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10875746 0.903 rs12304476 chr12:48482153 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs2456568 0.900 rs2511376 chr11:93670388 C/T cg17595323 chr11:93583763 C11orf90 -0.46 -5.86 -0.47 3.97e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs57221529 0.655 rs11948381 chr5:568413 A/T cg11887960 chr12:57824829 NA 1.02 7.66 0.57 4.52e-12 Lung disease severity in cystic fibrosis; TGCT cis rs12477438 0.561 rs2084988 chr2:99655755 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs11696501 0.694 rs6073827 chr20:44265556 T/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs2153535 0.580 rs9406171 chr6:8515362 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs1801251 1.000 rs283468 chr2:233658309 C/T cg08000102 chr2:233561755 GIGYF2 0.62 6.15 0.48 9.79e-9 Coronary artery disease; TGCT cis rs7104764 0.957 rs10794301 chr11:220401 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.05 10.74 0.69 2e-19 Menarche (age at onset); TGCT cis rs916888 0.610 rs199446 chr17:44813169 G/A cg01570182 chr17:44337453 NA -0.78 -7.51 -0.56 1.01e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12210905 0.688 rs12213533 chr6:27346021 C/T cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs9611565 0.532 rs4401299 chr22:42156517 A/G cg06634786 chr22:41940651 POLR3H 0.78 7.17 0.54 5.91e-11 Vitiligo; TGCT cis rs3818285 0.515 rs4918471 chr10:111660500 C/A cg00817464 chr10:111662876 XPNPEP1 -0.29 -4.94 -0.41 2.51e-6 Superior crus of antihelix expression; TGCT cis rs3087591 0.683 rs12602834 chr17:29637308 G/A cg24425628 chr17:29625626 OMG;NF1 0.41 6.01 0.47 1.93e-8 Hip circumference; TGCT cis rs7552404 0.924 rs3818855 chr1:76198785 C/T cg03433033 chr1:76189801 ACADM 0.82 9.87 0.66 2.55e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1008375 1.000 rs28480159 chr4:17685707 A/C cg10189774 chr4:17578691 LAP3 0.52 4.74 0.39 5.82e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs9913156 0.707 rs72835625 chr17:4560274 G/A cg23387401 chr17:4582204 PELP1 0.31 4.57 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg17971929 chr21:40555470 PSMG1 -0.67 -6.15 -0.48 9.72e-9 Cognitive function; TGCT cis rs8177179 0.505 rs1405023 chr3:133481128 T/C cg08048268 chr3:133502702 NA 0.44 5.16 0.42 9.47e-7 Iron status biomarkers (transferrin levels); TGCT cis rs4273100 0.564 rs10445411 chr17:19265797 C/T cg03910582 chr17:19030146 GRAPL -0.51 -6.67 -0.51 7.46e-10 Schizophrenia; TGCT cis rs939563 0.894 rs2302460 chr17:1444702 C/T cg04957132 chr17:1395371 MYO1C 0.28 4.49 0.37 1.61e-5 Mean platelet volume; TGCT cis rs2985684 0.948 rs4900925 chr14:50012325 A/G cg04989706 chr14:50066350 PPIL5 0.57 4.86 0.4 3.47e-6 Carotid intima media thickness; TGCT cis rs9611519 0.828 rs4822008 chr22:41539206 C/G cg03806693 chr22:41940476 POLR3H -0.67 -6.23 -0.49 6.64e-9 Neuroticism; TGCT cis rs6089584 1.000 rs6142910 chr20:60562181 C/A cg13770153 chr20:60521292 NA -0.44 -5.62 -0.45 1.21e-7 Body mass index; TGCT cis rs9650657 0.615 rs11986935 chr8:10691549 T/A cg16664915 chr8:10907788 XKR6 -0.29 -4.68 -0.39 7.26e-6 Neuroticism; TGCT cis rs9560113 1.000 rs914026 chr13:112182029 G/A cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs6582630 0.519 rs8189461 chr12:38374870 G/T cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs28735056 0.563 rs12968139 chr18:77685520 A/G cg20368463 chr18:77673604 PQLC1 -0.47 -5.52 -0.44 1.86e-7 Schizophrenia; TGCT cis rs548987 0.529 rs651578 chr6:25873883 T/C cg03517284 chr6:25882590 NA -0.64 -5.44 -0.44 2.77e-7 Homocysteine levels; TGCT cis rs6088580 0.634 rs6142157 chr20:32984172 C/G cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs9534288 0.699 rs9567621 chr13:46665814 A/G cg15192986 chr13:46630673 CPB2 -0.49 -5.83 -0.46 4.48e-8 Blood protein levels; TGCT cis rs9527 0.615 rs17725614 chr10:104685493 G/C cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs433598 0.894 rs180149 chr16:20676969 G/A cg16616769 chr16:19727142 IQCK;C16orf88 -0.2 -4.47 -0.37 1.71e-5 Schizophrenia; TGCT cis rs79976124 0.837 rs11751145 chr6:66642039 T/C cg07460842 chr6:66804631 NA 0.59 5.31 0.43 4.8e-7 Type 2 diabetes; TGCT cis rs7523273 0.568 rs55935450 chr1:208018779 T/A cg22525895 chr1:207977042 MIR29B2 -0.44 -6.18 -0.49 8.56e-9 Schizophrenia; TGCT cis rs9818758 0.556 rs9814987 chr3:49207849 T/C cg00383909 chr3:49044727 WDR6 1.28 6.68 0.51 7.04e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4294134 0.608 rs35357843 chr7:135245068 T/C cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs60843830 1.000 rs7605824 chr2:280819 A/G cg00108164 chr2:264199 ACP1;SH3YL1 -0.69 -6.52 -0.51 1.61e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs896854 0.552 rs2515236 chr8:95934907 A/G cg13393036 chr8:95962371 TP53INP1 0.53 6.41 0.5 2.73e-9 Type 2 diabetes; TGCT cis rs4808199 0.793 rs12459676 chr19:19425141 A/T cg20644253 chr19:19431407 KIAA0892;SF4 0.75 5.3 0.43 5.06e-7 Nonalcoholic fatty liver disease; TGCT cis rs11621121 0.637 rs4902388 chr14:65792852 A/G cg04536575 chr14:65016802 C14orf50 -0.64 -4.53 -0.38 1.36e-5 N-glycan levels; TGCT cis rs428668 0.681 rs192193 chr5:150692590 A/G cg11125805 chr5:150678162 SLC36A3 0.27 6.08 0.48 1.35e-8 Skin aging (microtopography measurement); TGCT cis rs10791097 0.547 rs10791101 chr11:130739133 C/T cg05962950 chr11:130786565 SNX19 0.93 11.63 0.72 1.37e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9581857 0.512 rs2057523 chr13:28073816 T/C cg22138327 chr13:27999177 GTF3A 0.85 6.02 0.48 1.87e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs910316 0.737 rs175055 chr14:75488946 T/G cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.36e-7 Height; TGCT cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg23188684 chr11:67383651 NA 0.31 4.73 0.39 5.95e-6 Mean corpuscular volume; TGCT cis rs7666738 0.791 rs1559860 chr4:99024422 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs13113899 chr4:99050422 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg09323728 chr8:95962352 TP53INP1 -0.54 -6.92 -0.53 2.17e-10 Type 2 diabetes; TGCT cis rs2228479 0.702 rs11076620 chr16:89831520 A/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs75686122 0.892 rs79348688 chr8:104594128 G/A cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs8177253 0.511 rs9830001 chr3:133433470 A/G cg08439880 chr3:133502540 NA 0.25 4.49 0.37 1.58e-5 Iron status biomarkers; TGCT cis rs6484504 0.576 rs158136 chr11:31220712 C/T cg26647111 chr11:31128758 NA -0.34 -4.62 -0.38 9.36e-6 Red blood cell count; TGCT cis rs6565180 0.507 rs4471699 chr16:30320307 G/T cg17640201 chr16:30407289 ZNF48 -0.69 -7.07 -0.54 9.81e-11 Tonsillectomy; TGCT cis rs2070433 1.000 rs2070433 chr21:47961386 G/A cg12379764 chr21:47803548 PCNT 0.53 4.5 0.37 1.54e-5 Lymphocyte counts; TGCT cis rs7666738 0.791 rs7684521 chr4:99071219 A/G cg18180107 chr4:99064573 C4orf37 0.56 5.0 0.41 1.9e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs915352 chr6:8442766 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT trans rs1814175 0.817 rs1794164 chr11:49899610 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.04 -0.53 1.16e-10 Height; TGCT cis rs12530845 0.767 rs7784162 chr7:135305886 G/T cg23117316 chr7:135346802 PL-5283 -0.55 -5.3 -0.43 5.04e-7 Red blood cell traits; TGCT cis rs950776 0.518 rs12907169 chr15:78825498 G/C cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs1878931 0.507 rs11648783 chr16:3406626 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.64 4.89 0.4 3.01e-6 Body mass index (adult); TGCT cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg11845111 chr2:191398756 TMEM194B 0.37 5.65 0.45 1.03e-7 Pulse pressure; TGCT cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg04944784 chr2:26401820 FAM59B -0.77 -6.49 -0.5 1.84e-9 Gut microbiome composition (summer); TGCT cis rs9486719 0.947 rs2472893 chr6:96870048 G/C cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7267979 1.000 rs6132835 chr20:25434667 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.790 rs11760 chr6:146205973 G/T cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6121246 0.909 rs6060929 chr20:30345914 C/T cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT trans rs916888 0.773 rs199451 chr17:44801784 G/A cg01341218 chr17:43662625 NA 1.09 8.7 0.62 1.73e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs380904 0.926 rs7842979 chr8:144601896 T/G cg22012530 chr8:144635309 GSDMD 0.47 4.68 0.39 7.27e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg11003573 chr3:44754125 ZNF502 -0.4 -4.55 -0.38 1.28e-5 Depressive symptoms; TGCT cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs617219 0.710 rs10805925 chr5:78539399 A/G cg09550809 chr5:78407562 BHMT 0.36 4.99 0.41 2.03e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7647973 0.710 rs9869120 chr3:49624065 T/C cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs11785400 0.793 rs34875149 chr8:143736131 G/A cg24634471 chr8:143751801 JRK 0.54 5.33 0.43 4.51e-7 Schizophrenia; TGCT cis rs9486719 1.000 rs4262195 chr6:96929475 T/C cg18709589 chr6:96969512 KIAA0776 -0.72 -5.24 -0.43 6.58e-7 Migraine;Coronary artery disease; TGCT cis rs12497850 0.931 rs1134591 chr3:48972892 C/T cg07636037 chr3:49044803 WDR6 0.99 10.32 0.68 2.16e-18 Parkinson's disease; TGCT cis rs11785693 0.862 rs73189843 chr8:5000915 C/T cg26367366 chr8:4980734 NA 0.58 4.59 0.38 1.06e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs11722228 1.000 rs6825187 chr4:9915325 T/C cg00071950 chr4:10020882 SLC2A9 -0.45 -4.58 -0.38 1.11e-5 Gout;Urate levels;Serum uric acid levels; TGCT cis rs826838 0.967 rs1684415 chr12:39130099 T/C cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs4148883 0.615 rs2187483 chr4:100134103 G/T cg12011299 chr4:100065546 ADH4 -0.33 -4.89 -0.4 3.06e-6 Alcohol dependence; TGCT cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg06634786 chr22:41940651 POLR3H 0.85 8.04 0.59 6.2e-13 Vitiligo; TGCT cis rs2980439 0.818 rs2945249 chr8:8094726 G/A cg15556689 chr8:8085844 FLJ10661 0.86 9.14 0.63 1.49e-15 Neuroticism; TGCT cis rs10031466 0.935 rs902909 chr4:189021465 A/G cg14506195 chr4:188913931 NA 0.24 4.51 0.38 1.49e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs8020441 0.838 rs72681662 chr14:51163884 G/A cg04730355 chr14:51134070 SAV1 0.73 6.01 0.47 1.96e-8 Cognitive performance; TGCT cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg18252515 chr7:66147081 NA -1.14 -6.81 -0.52 3.76e-10 Diabetic kidney disease; TGCT cis rs12643440 0.538 rs1522079 chr4:17134960 A/G cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs7666738 0.830 rs28587201 chr4:98991733 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs737008 0.960 rs34764020 chr16:11378359 C/T cg00044050 chr16:11439710 C16orf75 -0.72 -7.32 -0.55 2.69e-11 Obesity-related traits; TGCT cis rs4776059 1.000 rs35372377 chr15:52882281 G/A cg25063058 chr15:52860530 ARPP19 0.52 4.68 0.39 7.54e-6 Schizophrenia; TGCT cis rs10779751 0.726 rs1205593 chr1:11252716 T/C cg08854313 chr1:11322531 MTOR 0.87 6.93 0.53 2.02e-10 Body mass index; TGCT cis rs6459788 0.720 rs11768765 chr7:157253133 C/T cg03453431 chr7:157225567 NA -0.39 -5.91 -0.47 3.16e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7178572 0.568 rs12908262 chr15:77493256 G/A cg15453836 chr15:77711506 NA -0.44 -4.91 -0.4 2.86e-6 Type 2 diabetes; TGCT trans rs7726839 0.540 rs61731455 chr5:665295 A/G cg25482853 chr8:67687455 SGK3 1.19 10.53 0.69 6.56e-19 Obesity-related traits; TGCT cis rs875971 0.862 rs2088655 chr7:65795711 T/C cg11764359 chr7:65958608 NA -0.55 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs9291683 0.530 rs882223 chr4:9981625 A/C cg11266682 chr4:10021025 SLC2A9 0.62 8.63 0.61 2.51e-14 Bone mineral density; TGCT cis rs617791 0.508 rs1047464 chr11:65769456 A/T cg09783858 chr11:65769428 EIF1AD;BANF1 0.49 4.49 0.37 1.64e-5 Breast cancer; TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg14624950 chr17:62577106 SMURF2 -0.19 -4.46 -0.37 1.81e-5 Prudent dietary pattern; TGCT cis rs6912958 0.712 rs6454638 chr6:88329427 C/T cg06598631 chr6:88300029 RARS2;ORC3L 0.53 4.87 0.4 3.38e-6 Monocyte percentage of white cells; TGCT cis rs1023500 0.506 rs6002625 chr22:42517689 A/G cg15557168 chr22:42548783 NA 0.21 5.32 0.43 4.7e-7 Schizophrenia; TGCT cis rs933688 0.639 rs332530 chr5:90789810 G/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.95 8.24 0.59 2.11e-13 Smoking behavior; TGCT cis rs76473307 1.000 rs116642297 chr20:57409750 T/C cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs6558174 0.930 rs1038311 chr8:22489247 T/C cg03733263 chr8:22462867 KIAA1967 0.68 5.47 0.44 2.42e-7 Breast cancer; TGCT cis rs6770219 0.516 rs11926434 chr3:186135861 A/G cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs11992186 0.570 rs17628941 chr8:8587534 G/C cg17143192 chr8:8559678 CLDN23 -0.51 -5.01 -0.41 1.82e-6 Neuroticism; TGCT cis rs8180040 0.966 rs11716763 chr3:47518266 C/T cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs3824867 0.920 rs9734013 chr11:47451517 G/T cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs7786808 0.508 rs896765 chr7:158182809 G/A cg01191920 chr7:158217561 PTPRN2 0.35 4.96 0.41 2.26e-6 Obesity-related traits; TGCT cis rs7119 0.604 rs2682921 chr15:77865459 C/T cg27398640 chr15:77910606 LINGO1 0.27 4.78 0.39 4.92e-6 Type 2 diabetes; TGCT cis rs17767294 0.708 rs72851160 chr6:28067841 T/G cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs4808199 0.948 rs2074300 chr19:19380996 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.22 0.42 7.2e-7 Nonalcoholic fatty liver disease; TGCT cis rs1862618 0.671 rs2591955 chr5:56244948 C/T cg12311346 chr5:56204834 C5orf35 0.57 6.09 0.48 1.28e-8 Initial pursuit acceleration; TGCT cis rs61931739 0.500 rs6488218 chr12:34452587 T/C cg06521331 chr12:34319734 NA -0.28 -4.44 -0.37 1.94e-5 Morning vs. evening chronotype; TGCT cis rs7178572 0.568 rs12909924 chr15:77551445 T/G cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs909002 0.849 rs1464306 chr1:32076261 T/C cg11573219 chr1:32083031 HCRTR1 -0.49 -6.41 -0.5 2.73e-9 Intelligence (multi-trait analysis); TGCT cis rs523522 0.962 rs9788155 chr12:120938408 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs617219 0.659 rs13182512 chr5:78573790 A/T cg23987322 chr5:78407566 BHMT -0.35 -4.69 -0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9902453 0.791 rs3098950 chr17:27998385 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.29 0.6 1.61e-13 Coffee consumption (cups per day); TGCT cis rs13401104 0.587 rs55801537 chr2:237145481 C/T cg26422059 chr2:237146110 ASB18 0.57 4.56 0.38 1.19e-5 Educational attainment; TGCT cis rs2050392 0.517 rs619864 chr10:30750950 A/G cg18806716 chr10:30721971 MAP3K8 0.57 6.95 0.53 1.88e-10 Inflammatory bowel disease; TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg03173502 chr6:15505345 JARID2 0.9 5.41 0.44 3.17e-7 Gambling; TGCT cis rs7914558 1.000 rs4917996 chr10:104925829 A/C cg04362960 chr10:104952993 NT5C2 0.61 5.45 0.44 2.6e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4927850 0.881 rs7624638 chr3:195748729 C/T cg02975922 chr3:195473998 MUC4 -0.24 -5.44 -0.44 2.69e-7 Pancreatic cancer; TGCT cis rs2463822 0.669 rs72919475 chr11:62042361 T/A cg06239285 chr11:62104954 ASRGL1 -0.84 -5.17 -0.42 9.26e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT trans rs1499614 1.000 rs2707830 chr7:66167645 T/C cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs797680 0.856 rs687394 chr1:93713917 G/A cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6988636 1.000 rs11988157 chr8:124194740 A/G cg27053337 chr8:124217698 FAM83A -0.61 -5.17 -0.42 9.04e-7 Urinary uromodulin levels; TGCT cis rs9302065 0.565 rs2992910 chr13:95962216 T/A cg26751094 chr13:95954534 ABCC4 -0.4 -6.74 -0.52 5.33e-10 Blood metabolite levels; TGCT cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg07061783 chr6:25882402 NA 0.72 7.44 0.56 1.44e-11 Blood metabolite levels; TGCT cis rs9810089 0.934 rs1153877 chr3:136004925 C/T cg12473912 chr3:136751656 NA 0.35 4.98 0.41 2.05e-6 Gestational age at birth (child effect); TGCT cis rs8020441 0.686 rs6572687 chr14:51165438 G/C cg04730355 chr14:51134070 SAV1 0.7 5.79 0.46 5.45e-8 Cognitive performance; TGCT cis rs225245 0.782 rs321601 chr17:33892087 A/C cg05299278 chr17:33885742 SLFN14 -0.21 -4.73 -0.39 6.08e-6 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT trans rs208520 0.661 rs150263 chr6:66777620 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.86 -0.7 1.03e-19 Exhaled nitric oxide output; TGCT trans rs4824093 0.610 rs3761496 chr22:50246466 T/C cg09872104 chr7:134855509 C7orf49 -0.96 -7.87 -0.58 1.49e-12 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs2688608 0.967 rs9971038 chr10:75661149 C/T cg02947784 chr10:75434997 AGAP5 0.16 4.51 0.38 1.46e-5 Inflammatory bowel disease; TGCT cis rs10206020 0.921 rs72776300 chr2:1571152 A/G cg12573674 chr2:1569213 NA -0.49 -5.3 -0.43 5.1e-7 IgG glycosylation; TGCT cis rs7615952 0.736 rs9866347 chr3:125669925 C/T cg05084668 chr3:125655381 ALG1L -0.77 -5.24 -0.43 6.74e-7 Blood pressure (smoking interaction); TGCT cis rs10510102 0.872 rs11200268 chr10:123692176 C/T cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs2832077 0.506 rs2832093 chr21:30164855 C/T cg24692254 chr21:30365293 RNF160 -0.59 -5.22 -0.42 7.35e-7 Cognitive test performance; TGCT cis rs9583531 0.527 rs2391866 chr13:111363294 A/T cg24331049 chr13:111365604 ING1 0.77 7.3 0.55 2.96e-11 Coronary artery disease; TGCT cis rs28595532 0.920 rs114696063 chr4:119760624 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs8180040 0.966 rs56351005 chr3:47430186 G/T cg27129171 chr3:47204927 SETD2 -0.64 -7.39 -0.55 1.89e-11 Colorectal cancer; TGCT cis rs35146811 0.735 rs1138417 chr7:99807146 C/G cg04778012 chr7:99775508 STAG3;GPC2 -0.33 -4.76 -0.39 5.35e-6 Coronary artery disease; TGCT cis rs3741404 0.620 rs2236647 chr11:63964605 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.75 -7.6 -0.56 6.31e-12 Platelet count; TGCT trans rs1814175 0.817 rs10769618 chr11:49822336 A/G cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg13395646 chr4:1353034 KIAA1530 -0.38 -4.71 -0.39 6.41e-6 Longevity; TGCT cis rs9467773 1.000 rs9467773 chr6:26498426 A/G cg15659132 chr6:26577336 NA 0.84 11.93 0.73 2.59e-22 Intelligence (multi-trait analysis); TGCT cis rs2749592 0.550 rs4934881 chr10:37914346 A/C cg25427524 chr10:38739819 LOC399744 0.32 5.79 0.46 5.38e-8 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs4711350 0.906 rs10947446 chr6:33791998 G/A cg18005901 chr6:33739558 LEMD2 -0.56 -5.47 -0.44 2.43e-7 Schizophrenia; TGCT cis rs617219 0.737 rs12659709 chr5:78458257 C/G cg09550809 chr5:78407562 BHMT 0.4 5.67 0.45 9.51e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs875971 1.000 rs1540651 chr7:65650121 C/T cg18876405 chr7:65276391 NA -0.33 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs7819412 0.645 rs10156356 chr8:11046209 T/C cg21775007 chr8:11205619 TDH -0.52 -4.73 -0.39 5.92e-6 Triglycerides; TGCT cis rs908922 0.676 rs6674451 chr1:152531054 C/T cg20991723 chr1:152506922 NA 0.45 6.05 0.48 1.6e-8 Hair morphology; TGCT cis rs10751667 0.666 rs7105477 chr11:964271 C/G cg06064525 chr11:970664 AP2A2 -0.35 -8.12 -0.59 3.98e-13 Alzheimer's disease (late onset); TGCT cis rs1797081 0.967 rs780632 chr10:16861400 A/G cg23933602 chr10:16859644 RSU1 -1.03 -12.13 -0.74 8.13e-23 Platelet distribution width; TGCT cis rs3816788 0.837 rs6557640 chr8:21771731 A/T cg17168535 chr8:21777572 XPO7 0.77 7.4 0.55 1.81e-11 Lung cancer in ever smokers; TGCT cis rs12497850 1.000 rs12497850 chr3:48748989 G/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.94 0.47 2.65e-8 Parkinson's disease; TGCT trans rs7824557 0.505 rs2736313 chr8:11086942 C/T cg06636001 chr8:8085503 FLJ10661 0.8 7.32 0.55 2.69e-11 Retinal vascular caliber; TGCT trans rs7618501 0.633 rs2624843 chr3:49997963 G/A cg21659725 chr3:3221576 CRBN 0.76 9.03 0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs951366 0.870 rs3747973 chr1:205677148 A/G cg14159672 chr1:205819179 PM20D1 0.43 4.56 0.38 1.19e-5 Menarche (age at onset); TGCT cis rs6684514 1.000 rs12038481 chr1:156284815 T/C cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7940866 0.834 rs10894302 chr11:130861994 C/T cg05962950 chr11:130786565 SNX19 0.73 7.02 0.53 1.27e-10 Schizophrenia; TGCT cis rs758129 0.501 rs2351002 chr15:89869329 C/G cg24365117 chr15:89879190 POLG 0.34 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs11895698 1 rs11895698 chr2:239338495 C/T cg08773314 chr2:239334832 ASB1 -0.46 -4.49 -0.37 1.64e-5 Chronotype; TGCT cis rs9858542 1.000 rs9822268 chr3:49719729 G/A cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6964587 1.000 rs7781066 chr7:91691946 G/T cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs854765 0.583 rs7213225 chr17:17869111 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs7772486 0.597 rs2485631 chr6:146190077 G/C cg05347473 chr6:146136440 FBXO30 0.67 6.25 0.49 6.04e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10986311 0.962 rs2068165 chr9:127088350 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.44 -0.37 1.97e-5 Vitiligo; TGCT cis rs3947 0.950 rs1293331 chr8:11698436 C/T cg02840367 chr8:11660030 FDFT1 0.91 6.65 0.51 8.45e-10 Blood protein levels; TGCT cis rs7666738 0.830 rs10034619 chr4:98970067 G/C cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs911263 0.961 rs1950897 chr14:68760141 C/T cg18825221 chr14:68749962 RAD51L1 0.28 5.47 0.44 2.36e-7 Primary biliary cholangitis; TGCT cis rs6121246 0.909 rs6060979 chr20:30417522 C/T cg18721089 chr20:30220636 NA -0.45 -5.04 -0.41 1.63e-6 Mean corpuscular hemoglobin; TGCT cis rs1981331 0.609 rs7282611 chr21:48043297 C/A cg23283320 chr21:48055893 PRMT2 1.35 6.43 0.5 2.51e-9 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs933688 1.000 rs2367353 chr5:90686568 G/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 9.55 0.65 1.57e-16 Smoking behavior; TGCT cis rs7267979 1.000 rs6050630 chr20:25430745 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1005277 0.579 rs2505248 chr10:38459097 A/G cg27523141 chr10:43048294 ZNF37B 0.74 8.34 0.6 1.22e-13 Extrinsic epigenetic age acceleration; TGCT cis rs12478296 1.000 rs55732177 chr2:243040006 C/T cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs4851266 1.000 rs11687241 chr2:100824595 A/G cg22139774 chr2:100720529 AFF3 -0.36 -5.4 -0.44 3.26e-7 Educational attainment; TGCT cis rs2836974 0.568 rs11910906 chr21:40685662 T/C cg17971929 chr21:40555470 PSMG1 -0.7 -6.32 -0.49 4.38e-9 Cognitive function; TGCT cis rs644799 0.930 rs631099 chr11:95563482 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs17376456 0.877 rs17374627 chr5:93296306 C/T cg21475434 chr5:93447410 FAM172A 0.64 4.66 0.39 8.1e-6 Diabetic retinopathy; TGCT cis rs2836950 0.502 rs12627205 chr21:40630027 C/T cg11890956 chr21:40555474 PSMG1 -0.71 -6.94 -0.53 1.94e-10 Menarche (age at onset); TGCT cis rs7829975 0.688 rs6995407 chr8:8384647 C/G cg06636001 chr8:8085503 FLJ10661 0.78 7.3 0.55 3.04e-11 Mood instability; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg11905131 chr22:24372483 LOC391322 -0.95 -11.1 -0.71 2.66e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs644799 1.000 rs534497 chr11:95562868 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs950776 0.616 rs3743077 chr15:78894896 C/T cg06917634 chr15:78832804 PSMA4 0.65 5.29 0.43 5.28e-7 Sudden cardiac arrest; TGCT cis rs9549367 0.789 rs6577034 chr13:113879900 T/C cg18105134 chr13:113819100 PROZ -0.34 -5.67 -0.45 9.36e-8 Platelet distribution width; TGCT cis rs67072384 1.000 rs7122017 chr11:72448558 C/G cg03713592 chr11:72463424 ARAP1 -0.94 -4.8 -0.4 4.41e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs9928842 0.823 rs889514 chr16:75272512 A/G cg09066997 chr16:75300724 BCAR1 0.27 4.86 0.4 3.45e-6 Alcoholic chronic pancreatitis; TGCT cis rs208520 0.661 rs4710566 chr6:66848538 G/A cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs71435601 0.628 rs560522 chr2:21382363 A/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs902774 0.597 rs7299694 chr12:53352572 A/C cg25025879 chr12:53359317 NA -0.44 -4.87 -0.4 3.39e-6 Prostate cancer; TGCT cis rs7432375 0.579 rs10935199 chr3:136563535 G/C cg12473912 chr3:136751656 NA 0.33 4.6 0.38 1.01e-5 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs4862307 0.733 rs28631204 chr4:184996363 T/G cg06737308 chr4:185021514 ENPP6 0.32 4.55 0.38 1.28e-5 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs1371867 0.846 rs1660316 chr8:101333049 T/C cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs4523957 0.620 rs8064309 chr17:2059961 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3540 0.960 rs2238325 chr15:91011262 C/T cg22089800 chr15:90895588 ZNF774 -0.76 -7.03 -0.53 1.21e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs3784262 0.740 rs12917536 chr15:58288247 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.95 -0.47 2.58e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9787249 0.957 rs7547787 chr1:40220806 C/T cg19912559 chr1:40204330 PPIE 0.49 5.61 0.45 1.26e-7 Blood protein levels; TGCT cis rs6582630 0.560 rs4882325 chr12:38510037 C/T cg26384229 chr12:38710491 ALG10B -0.55 -4.91 -0.4 2.86e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2066819 1.000 rs57137641 chr12:56741228 G/A cg26714650 chr12:56694279 CS -1.36 -5.95 -0.47 2.56e-8 Psoriasis vulgaris; TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.12 15.93 0.82 8.93e-32 Prudent dietary pattern; TGCT cis rs12908161 0.920 rs35758837 chr15:85311382 C/T cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.04e-8 Schizophrenia; TGCT trans rs9929218 0.551 rs3785134 chr16:68728938 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.57 7.45 0.56 1.41e-11 Colorectal cancer; TGCT cis rs2486288 0.656 rs11632752 chr15:45551140 A/G cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs916888 0.821 rs415430 chr17:44859144 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9467773 0.836 rs1624440 chr6:26433329 G/A cg26531700 chr6:26746687 NA -0.5 -4.89 -0.4 3e-6 Intelligence (multi-trait analysis); TGCT cis rs11578119 0.866 rs10919375 chr1:170349137 A/G cg09767346 chr1:170501363 GORAB 0.61 4.57 0.38 1.16e-5 Male-pattern baldness; TGCT cis rs9818758 0.607 rs35108630 chr3:49088356 T/A cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs17376456 0.877 rs10076052 chr5:93317762 C/T cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs116095464 0.558 rs34629844 chr5:200829 A/G cg22857025 chr5:266934 NA -0.33 -6.25 -0.49 6.09e-9 Breast cancer; TGCT cis rs514406 0.505 rs395169 chr1:53174071 G/A cg08859206 chr1:53392774 SCP2 -0.35 -4.99 -0.41 2.03e-6 Monocyte count; TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg02073558 chr3:44770973 ZNF501 0.69 7.01 0.53 1.37e-10 Depressive symptoms; TGCT cis rs10057188 1.000 rs12697889 chr5:77870700 G/A cg06873401 chr5:77792105 LHFPL2 -0.22 -4.46 -0.37 1.79e-5 Pulse pressure; TGCT cis rs3617 0.625 rs11922961 chr3:52868610 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7267979 0.833 rs4619688 chr20:25244101 C/G cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11190604 1.000 rs4919470 chr10:102298920 C/T cg23241863 chr10:102295624 HIF1AN 0.67 4.8 0.4 4.46e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs8177253 0.931 rs8177256 chr3:133480276 G/T cg08048268 chr3:133502702 NA -0.65 -9.83 -0.66 3.21e-17 Iron status biomarkers; TGCT cis rs916888 0.821 rs70602 chr17:44859715 T/C cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs1005277 0.522 rs7090858 chr10:38003670 A/C cg17830980 chr10:43048298 ZNF37B 0.67 7.5 0.56 1.06e-11 Extrinsic epigenetic age acceleration; TGCT cis rs7589728 0.563 rs12479338 chr2:88444513 C/T cg04511125 chr2:88470314 THNSL2 0.79 6.55 0.51 1.37e-9 Plasma clusterin levels; TGCT cis rs877282 0.891 rs11253406 chr10:796297 G/A cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs4862750 0.914 rs10027250 chr4:187873460 T/C cg11301795 chr4:187892539 NA -0.34 -5.14 -0.42 1.06e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7552404 1.000 rs7534754 chr1:76185308 G/A cg22875332 chr1:76189707 ACADM 0.79 9.69 0.66 7.25e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9527 0.590 rs1935323 chr10:104877035 T/C cg04362960 chr10:104952993 NT5C2 0.68 5.82 0.46 4.81e-8 Arsenic metabolism; TGCT cis rs854765 0.547 rs4365348 chr17:17912548 C/T cg09796270 chr17:17721594 SREBF1 0.25 5.03 0.41 1.71e-6 Total body bone mineral density; TGCT cis rs713587 0.691 rs754536 chr2:25176200 C/T cg15423357 chr2:25149977 NA -0.46 -4.52 -0.38 1.41e-5 Body mass index in non-asthmatics; TGCT cis rs10504229 0.683 rs67492041 chr8:58140077 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs7727544 0.660 rs272886 chr5:131665840 T/C cg14196790 chr5:131705035 SLC22A5 0.32 4.53 0.38 1.34e-5 Blood metabolite levels; TGCT cis rs1670533 1.000 rs10084889 chr4:1053815 G/A cg27284194 chr4:1044797 NA 0.67 5.77 0.46 5.9e-8 Recombination rate (females); TGCT cis rs9457247 1.000 rs389946 chr6:167407268 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs8103278 0.507 rs10401971 chr19:46261982 C/T cg14061069 chr19:46274453 DMPK 0.63 10.79 0.7 1.51e-19 Coronary artery disease; TGCT cis rs6964587 1.000 rs10234071 chr7:91645152 C/G cg17063962 chr7:91808500 NA -0.92 -10.29 -0.68 2.52e-18 Breast cancer; TGCT cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs1538970 0.924 rs4660858 chr1:45936351 G/A cg05343316 chr1:45956843 TESK2 0.74 6.09 0.48 1.28e-8 Platelet count; TGCT cis rs589448 0.535 rs12423794 chr12:69713018 G/A cg14784868 chr12:69753453 YEATS4 0.75 8.07 0.59 5.17e-13 Cerebrospinal fluid biomarker levels; TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs992157 1.000 rs992157 chr2:219154781 A/G cg00012203 chr2:219082015 ARPC2 -0.74 -7.91 -0.58 1.23e-12 Colorectal cancer; TGCT cis rs8028182 0.525 rs9920028 chr15:75927717 G/A cg20655648 chr15:75932815 IMP3 0.54 4.44 0.37 1.99e-5 Sudden cardiac arrest; TGCT cis rs7937682 0.883 rs553632 chr11:111462897 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs1218582 0.741 rs7544528 chr1:154844585 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.65 -6.34 -0.49 3.92e-9 Prostate cancer; TGCT cis rs7635838 0.785 rs904475 chr3:11535417 G/A cg00170343 chr3:11313890 ATG7 0.69 6.42 0.5 2.58e-9 HDL cholesterol; TGCT cis rs35160687 0.901 rs12620833 chr2:86472870 T/C cg12542933 chr2:85804724 VAMP8 0.41 4.88 0.4 3.25e-6 Night sleep phenotypes; TGCT cis rs9318086 0.712 rs9510916 chr13:24442789 C/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.77 8.28 0.6 1.69e-13 Myopia (pathological); TGCT cis rs2239547 0.563 rs4687699 chr3:53101224 C/T cg10802521 chr3:52805072 NEK4 -0.59 -5.46 -0.44 2.45e-7 Schizophrenia; TGCT cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg13393036 chr8:95962371 TP53INP1 -0.62 -8.55 -0.61 3.83e-14 Type 2 diabetes; TGCT cis rs3617 0.625 rs6445541 chr3:52880128 G/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.69 -0.39 7.05e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2658782 0.901 rs7116173 chr11:93222311 C/T cg26827247 chr11:93063208 CCDC67 0.57 4.45 0.37 1.9e-5 Pulmonary function decline; TGCT cis rs3796352 0.892 rs2581807 chr3:53088844 G/A cg07884673 chr3:53033167 SFMBT1 -0.58 -6.25 -0.49 5.99e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10504229 0.679 rs16921676 chr8:58052386 G/T cg08219700 chr8:58056026 NA 0.29 4.44 0.37 1.93e-5 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.702 rs72670252 chr4:119337546 A/C cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg06873352 chr17:61820015 STRADA -0.49 -5.47 -0.44 2.33e-7 Prudent dietary pattern; TGCT cis rs909674 0.514 rs7423 chr22:39781429 C/T cg01416388 chr22:39784598 NA -0.64 -6.48 -0.5 1.95e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2836974 0.666 rs11910705 chr21:40685604 C/T cg11890956 chr21:40555474 PSMG1 -0.78 -7.37 -0.55 2.08e-11 Cognitive function; TGCT cis rs6714710 0.603 rs2278700 chr2:98427382 T/C cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs11578119 0.933 rs10919423 chr1:170480531 C/T cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs6964587 0.933 rs6465350 chr7:91768615 G/A cg22709100 chr7:91322751 NA 0.29 4.68 0.39 7.29e-6 Breast cancer; TGCT cis rs9911578 1.000 rs12453049 chr17:56611372 C/T cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs6921919 0.583 rs2071965 chr6:28403225 C/T cg18815343 chr6:28367644 ZSCAN12 -0.53 -5.12 -0.42 1.15e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs611744 0.868 rs612722 chr8:109194850 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg11494091 chr17:61959527 GH2 -0.61 -16.1 -0.82 3.53e-32 Prudent dietary pattern; TGCT cis rs7095607 0.813 rs4584466 chr10:69933132 C/G cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.73e-6 Lung function (FVC); TGCT cis rs362296 0.698 rs3095083 chr4:3263499 G/A cg06533319 chr4:3265114 C4orf44 0.23 4.64 0.38 8.9e-6 Parental longevity (mother's age at death); TGCT cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg23758822 chr17:41437982 NA 0.73 7.03 0.53 1.2e-10 Menopause (age at onset); TGCT cis rs12900413 0.603 rs4448912 chr15:90299690 G/A cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs250677 0.687 rs36044 chr5:148441128 T/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg27588902 chr6:42928151 GNMT 0.56 6.93 0.53 2.08e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4780401 0.632 rs7192366 chr16:11835209 C/G cg01061890 chr16:11836724 TXNDC11 -0.63 -6.09 -0.48 1.32e-8 Rheumatoid arthritis; TGCT cis rs7666738 0.830 rs10025174 chr4:98914172 A/G cg05340658 chr4:99064831 C4orf37 0.54 6.51 0.5 1.7e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2832191 0.935 rs67287920 chr21:30523519 C/A cg08807101 chr21:30365312 RNF160 -0.52 -4.87 -0.4 3.27e-6 Dental caries; TGCT cis rs9916302 0.861 rs2338801 chr17:37490780 G/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg15242686 chr22:24348715 GSTTP1 0.43 5.95 0.47 2.57e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17767294 0.708 rs72851105 chr6:28036408 G/T cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs56334439 0.665 rs28716988 chr3:60108414 G/C cg17894779 chr3:60066405 FHIT -0.37 -4.94 -0.41 2.48e-6 Myringotomy; TGCT cis rs36051895 0.664 rs9695933 chr9:5153104 C/T cg02405213 chr9:5042618 JAK2 -0.73 -9.46 -0.65 2.54e-16 Pediatric autoimmune diseases; TGCT cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg12310025 chr6:25882481 NA -0.64 -6.66 -0.51 7.99e-10 Blood metabolite levels; TGCT cis rs909674 0.775 rs4821896 chr22:39833437 T/C cg02038168 chr22:39784481 NA -0.74 -5.58 -0.45 1.41e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT trans rs7819412 0.668 rs2409721 chr8:11038244 A/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.67 -0.51 7.51e-10 Triglycerides; TGCT cis rs9682041 0.660 rs13089074 chr3:170113481 G/A cg11886554 chr3:170076028 SKIL 0.62 4.82 0.4 4.11e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs9329289 0.926 rs10903784 chr10:2541943 G/T cg15501526 chr10:2543763 NA -0.42 -5.27 -0.43 5.91e-7 Age-related hearing impairment; TGCT trans rs7618501 0.699 rs9862795 chr3:49915506 A/T cg21665057 chr3:196295764 WDR53;FBXO45 0.89 9.83 0.66 3.23e-17 Intelligence (multi-trait analysis); TGCT cis rs3809566 1.000 rs4774471 chr15:63332645 A/T cg00520135 chr15:63333846 TPM1 0.45 5.55 0.45 1.65e-7 Platelet count; TGCT cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg14416726 chr6:151773293 C6orf211;RMND1 1.01 12.49 0.75 1.1e-23 Menarche (age at onset); TGCT cis rs12497850 0.865 rs13072911 chr3:48962128 T/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs1865760 0.865 rs9393678 chr6:25945819 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT cis rs4727027 0.866 rs10435245 chr7:148816081 C/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.64 0.38 8.88e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12681288 0.862 rs2600487 chr8:1016903 C/T cg06709756 chr8:1339049 NA -0.23 -4.54 -0.38 1.3e-5 Schizophrenia; TGCT cis rs77861329 1.000 rs9811707 chr3:52190657 G/A cg08692210 chr3:52188851 WDR51A 0.83 4.64 0.38 8.71e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs4242434 0.889 rs11785755 chr8:22453223 C/A cg03733263 chr8:22462867 KIAA1967 1.1 17.97 0.85 2.57e-36 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9952991 0.941 rs9952749 chr18:12780456 A/G cg09945482 chr18:12777974 NA 0.5 4.75 0.39 5.61e-6 Inflammatory skin disease; TGCT cis rs79149102 0.579 rs7172989 chr15:75295905 C/T cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs7586879 0.616 rs10203386 chr2:25136866 T/A cg01884057 chr2:25150051 NA 0.35 6.95 0.53 1.81e-10 Body mass index; TGCT cis rs6912958 0.525 rs586771 chr6:88064971 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.68 6.88 0.53 2.68e-10 Monocyte percentage of white cells; TGCT cis rs1990950 0.654 rs2161398 chr5:156838886 C/A cg25387487 chr5:157003181 ADAM19 0.29 4.54 0.38 1.29e-5 Lung function (FEV1/FVC); TGCT cis rs79349575 0.721 rs2291725 chr17:47039132 T/C cg00947319 chr17:47005597 UBE2Z -0.2 -4.5 -0.37 1.53e-5 Type 2 diabetes; TGCT cis rs1371867 0.846 rs1660351 chr8:101275034 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -6.83 -0.52 3.32e-10 Atrioventricular conduction; TGCT trans rs2727020 0.595 rs11040416 chr11:49566429 C/T cg03929089 chr4:120376271 NA -0.77 -9.31 -0.64 5.96e-16 Coronary artery disease; TGCT cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs56104184 0.725 rs1466896 chr19:49385253 C/G cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs9388451 0.872 rs2008027 chr6:126052359 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.1 -0.59 4.31e-13 Brugada syndrome; TGCT cis rs1865760 0.786 rs2164487 chr6:25950800 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT cis rs1691799 0.899 rs1177555 chr12:66727568 A/G cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.77e-9 White blood cell count (basophil); TGCT cis rs2075371 1.000 rs2598285 chr7:133971153 A/T cg11752832 chr7:134001865 SLC35B4 0.66 6.11 0.48 1.19e-8 Mean platelet volume; TGCT cis rs35306767 0.761 rs11253560 chr10:1047226 T/G cg18964960 chr10:1102726 WDR37 0.78 5.46 0.44 2.45e-7 Eosinophil percentage of granulocytes; TGCT cis rs1577917 0.958 rs1838955 chr6:86565449 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg24846343 chr22:24311635 DDTL 0.22 5.66 0.45 1e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6714710 0.603 rs7583868 chr2:98588372 C/A cg26665480 chr2:98280029 ACTR1B 0.63 5.98 0.47 2.19e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs644799 0.526 rs693172 chr11:95636618 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.49 4.93 0.4 2.63e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3008870 1.000 rs3008858 chr1:67390416 G/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs2075371 0.897 rs1643033 chr7:134004662 T/C cg11752832 chr7:134001865 SLC35B4 0.81 7.72 0.57 3.33e-12 Mean platelet volume; TGCT cis rs4851254 0.618 rs12996621 chr2:100646137 A/G cg22139774 chr2:100720529 AFF3 -0.47 -5.18 -0.42 8.65e-7 Intelligence (multi-trait analysis); TGCT cis rs3008870 0.958 rs34367328 chr1:67445321 T/C cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs9467773 1.000 rs4713006 chr6:26519872 A/G cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs17433780 0.860 rs10922545 chr1:89492201 C/T cg09516651 chr1:89888402 LOC400759 0.26 4.48 0.37 1.67e-5 Carotid intima media thickness; TGCT cis rs9929218 0.508 rs1559366 chr16:68799611 A/G cg01251360 chr16:68772225 CDH1 -0.25 -4.5 -0.37 1.53e-5 Colorectal cancer; TGCT cis rs4975709 0.589 rs4975747 chr5:1862836 G/A cg15595755 chr5:1867978 NA 0.45 5.28 0.43 5.66e-7 Cardiovascular disease risk factors; TGCT cis rs7511006 1.000 rs7511006 chr22:50676259 T/C cg08875078 chr22:50639485 SELO 0.51 4.81 0.4 4.23e-6 Obesity-related traits; TGCT cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg17554472 chr22:41940697 POLR3H -0.45 -4.67 -0.39 7.81e-6 Vitiligo; TGCT cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs4654899 0.802 rs4654724 chr1:21177210 C/T cg01072550 chr1:21505969 NA -0.45 -6.76 -0.52 4.8e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4319547 0.661 rs10773172 chr12:122939655 G/A cg23029597 chr12:123009494 RSRC2 -0.27 -4.44 -0.37 1.99e-5 Body mass index; TGCT cis rs3796352 1.000 rs13078971 chr3:53103645 G/C cg27565382 chr3:53032988 SFMBT1 0.45 4.76 0.39 5.2e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6450176 0.638 rs16881969 chr5:53300748 A/G ch.5.1024479R chr5:53302184 ARL15 0.63 4.68 0.39 7.44e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs682748 0.846 rs60388951 chr5:17134319 C/G cg23987134 chr5:17158319 LOC285696 -0.21 -5.11 -0.42 1.17e-6 Hippocampal atrophy; TGCT cis rs8013055 0.796 rs28662250 chr14:105996341 C/G cg19700328 chr14:106028568 NA -0.48 -5.13 -0.42 1.09e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.32 -0.43 4.69e-7 Developmental language disorder (linguistic errors); TGCT cis rs75557865 1 rs75557865 chr3:121652141 G/A cg20356878 chr3:121714668 ILDR1 0.51 6.56 0.51 1.33e-9 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2535633 0.631 rs2245424 chr3:53003021 G/C cg11645453 chr3:52864694 ITIH4 -0.27 -5.03 -0.41 1.68e-6 Body mass index; TGCT cis rs35883536 1.000 rs12239531 chr1:101085661 A/G cg06223162 chr1:101003688 GPR88 0.31 4.89 0.4 3.07e-6 Monocyte count; TGCT cis rs595982 0.559 rs117227130 chr19:49367959 A/G cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.25 -0.64 8.09e-16 Red cell distribution width; TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs881375 1.000 rs10117059 chr9:123653477 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.43 0.44 2.9e-7 Rheumatoid arthritis; TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs11264213 0.551 rs11263852 chr1:36554442 G/C cg27506609 chr1:36549197 TEKT2 -0.37 -5.96 -0.47 2.42e-8 Schizophrenia; TGCT cis rs7617773 0.817 rs3937 chr3:48312402 T/C cg11946769 chr3:48343235 NME6 0.72 6.2 0.49 7.83e-9 Coronary artery disease; TGCT cis rs1865760 0.568 rs2032450 chr6:25993114 C/G cg16482183 chr6:26056742 HIST1H1C 0.54 4.77 0.39 5.15e-6 Height; TGCT cis rs9611565 0.559 rs132765 chr22:42008068 A/G cg13695892 chr22:41940480 POLR3H 0.88 8.46 0.6 6.38e-14 Vitiligo; TGCT cis rs55962025 0.883 rs362275 chr4:3224602 C/T cg06533319 chr4:3265114 C4orf44 0.24 4.7 0.39 6.87e-6 Parental longevity (mother's age at death); TGCT cis rs10791097 0.694 rs3190331 chr11:130748131 C/T cg14779329 chr11:130786720 SNX19 -0.29 -5.11 -0.42 1.19e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6089829 0.962 rs9680064 chr20:61666168 G/A cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs9811920 0.609 rs6440938 chr3:99652092 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.77 0.52 4.51e-10 Axial length; TGCT cis rs6500602 0.727 rs2058811 chr16:4575162 C/T cg08645402 chr16:4508243 NA 0.19 5.25 0.43 6.37e-7 Schizophrenia; TGCT cis rs8179 0.700 rs42039 chr7:92244422 A/G cg15732164 chr7:92237376 CDK6 0.28 4.89 0.4 3.11e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.1 0.48 1.25e-8 Intelligence (multi-trait analysis); TGCT cis rs4654899 1.000 rs6682368 chr1:21506914 G/A cg01072550 chr1:21505969 NA -0.5 -8.08 -0.59 4.94e-13 Superior frontal gyrus grey matter volume; TGCT cis rs72945132 0.882 rs12294540 chr11:70118973 A/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7617773 0.817 rs13072018 chr3:48320332 G/A cg11946769 chr3:48343235 NME6 0.76 6.57 0.51 1.23e-9 Coronary artery disease; TGCT cis rs2730260 0.578 rs56375711 chr7:158854935 G/A cg02078164 chr7:157982224 PTPRN2 0.41 4.48 0.37 1.66e-5 Myopia (pathological); TGCT trans rs11158198 0.582 rs34548381 chr14:58621716 C/T cg18792904 chr6:83074812 TPBG 0.74 6.74 0.52 5.38e-10 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs739401 0.611 rs7130841 chr11:3043658 A/G cg05729581 chr11:3078854 CARS -0.54 -5.13 -0.42 1.07e-6 Longevity; TGCT cis rs1532993 0.518 rs9654187 chr4:98630909 G/T cg05340658 chr4:99064831 C4orf37 -0.4 -4.91 -0.4 2.77e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs801193 0.613 rs2659900 chr7:66184443 G/C cg11764359 chr7:65958608 NA 0.59 5.12 0.42 1.14e-6 Aortic root size; TGCT cis rs11098499 0.731 rs10015579 chr4:120271802 T/C cg09307838 chr4:120376055 NA 0.55 5.46 0.44 2.5e-7 Corneal astigmatism; TGCT cis rs317689 0.581 rs160829 chr12:69769538 G/C cg19645103 chr12:69753606 YEATS4 -0.57 -4.8 -0.4 4.5e-6 Response to diuretic therapy; TGCT cis rs2115630 0.846 rs8024538 chr15:85368419 A/T cg17173187 chr15:85201210 NMB -0.49 -5.99 -0.47 2.14e-8 P wave terminal force; TGCT cis rs10927875 0.541 rs1763599 chr1:16342602 C/T cg22431228 chr1:16359049 CLCNKA -0.29 -6.02 -0.48 1.8e-8 Dilated cardiomyopathy; TGCT cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT trans rs4650994 0.625 rs6681354 chr1:178526279 A/G cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.37e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7819412 0.669 rs4840549 chr8:10998955 A/G cg03192020 chr8:11204681 TDH -0.52 -4.5 -0.37 1.53e-5 Triglycerides; TGCT cis rs28735056 0.967 rs11660941 chr18:77630600 G/C cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs6714788 0.503 rs2309748 chr2:100681449 A/T cg07810366 chr2:100720526 AFF3 -0.37 -5.29 -0.43 5.31e-7 Intelligence (multi-trait analysis); TGCT cis rs10791323 0.628 rs1893850 chr11:133705356 T/C cg15485101 chr11:133734466 NA 0.4 5.08 0.42 1.34e-6 Childhood ear infection; TGCT trans rs6089829 0.888 rs4809268 chr20:61675249 C/G cg17470723 chr8:74884337 TCEB1 0.78 6.83 0.52 3.42e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs533581 0.866 rs502258 chr16:88968547 G/A cg05579598 chr16:88989069 CBFA2T3 0.36 4.45 0.37 1.88e-5 Social autistic-like traits; TGCT cis rs861020 0.959 rs641348 chr1:209992043 A/G cg05527609 chr1:210001259 C1orf107 0.95 7.67 0.57 4.35e-12 Orofacial clefts; TGCT cis rs12497850 1.000 rs12493578 chr3:48730116 C/T cg16497277 chr3:49208875 KLHDC8B 0.51 4.84 0.4 3.81e-6 Parkinson's disease; TGCT cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg20607798 chr8:58055168 NA 0.49 4.56 0.38 1.2e-5 Developmental language disorder (linguistic errors); TGCT cis rs2455799 0.613 rs13071730 chr3:15891035 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.68 -0.39 7.4e-6 Mean platelet volume; TGCT trans rs17685 0.712 rs4732578 chr7:75721532 A/G cg19862616 chr7:65841803 NCRNA00174 0.51 8.3 0.6 1.51e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6684514 1.000 rs3806407 chr1:156251742 T/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs11190604 0.767 rs77769532 chr10:102193646 T/C cg16005271 chr10:102321736 NA 0.46 4.69 0.39 6.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12142240 0.667 rs66990604 chr1:46822073 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg14983838 chr19:29218262 NA 0.83 6.85 0.52 3.07e-10 Methadone dose in opioid dependence; TGCT cis rs10045504 0.502 rs17456482 chr5:38737783 G/C cg15396434 chr5:38725168 NA -0.35 -4.47 -0.37 1.78e-5 Night sleep phenotypes; TGCT cis rs11785400 0.731 rs4644221 chr8:143736984 C/T cg24634471 chr8:143751801 JRK -0.54 -5.51 -0.44 1.95e-7 Schizophrenia; TGCT cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.04e-8 Bipolar disorder; TGCT cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg26531700 chr6:26746687 NA 0.51 4.64 0.38 8.75e-6 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs12497850 0.931 rs6414613 chr3:49035885 C/T cg07636037 chr3:49044803 WDR6 0.96 10.5 0.69 7.74e-19 Parkinson's disease; TGCT cis rs9291683 0.588 rs4280729 chr4:10013861 C/T cg00071950 chr4:10020882 SLC2A9 0.76 10.25 0.68 3.14e-18 Bone mineral density; TGCT cis rs877282 0.853 rs7092805 chr10:756246 G/A cg17470449 chr10:769945 NA 0.34 5.11 0.42 1.16e-6 Uric acid levels; TGCT cis rs3796352 0.527 rs11715498 chr3:52943551 G/C cg11137980 chr3:52469226 SEMA3G 0.28 4.65 0.39 8.22e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2239547 0.522 rs2336162 chr3:52951519 C/T cg11645453 chr3:52864694 ITIH4 -0.36 -6.24 -0.49 6.31e-9 Schizophrenia; TGCT cis rs45509595 0.841 rs2747054 chr6:27783359 A/G cg10876282 chr6:28092338 ZSCAN16 0.78 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs7772486 0.686 rs4896828 chr6:145953339 A/C cg05347473 chr6:146136440 FBXO30 0.48 4.56 0.38 1.19e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.655 rs4470201 chr17:17844870 G/A cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs1023500 0.573 rs133377 chr22:42466950 C/T cg05082376 chr22:42548792 NA -0.23 -5.43 -0.44 2.83e-7 Schizophrenia; TGCT cis rs8042680 0.554 rs8036115 chr15:91528961 G/A cg22570213 chr15:91497863 RCCD1 0.43 4.46 0.37 1.78e-5 Type 2 diabetes; TGCT cis rs734999 0.549 rs60733400 chr1:2516781 G/A cg18854424 chr1:2615690 NA 0.47 5.23 0.42 7.09e-7 Ulcerative colitis; TGCT cis rs9527 0.545 rs11191602 chr10:104954219 C/T cg04362960 chr10:104952993 NT5C2 0.68 5.73 0.46 7.14e-8 Arsenic metabolism; TGCT cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg09359103 chr1:154839909 KCNN3 0.44 6.1 0.48 1.22e-8 Schizophrenia; TGCT cis rs9467711 1.000 rs6923139 chr6:26313348 C/T cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs854765 0.647 rs854790 chr17:18028318 C/G cg04398451 chr17:18023971 MYO15A -0.4 -6.86 -0.52 2.96e-10 Total body bone mineral density; TGCT cis rs10992471 0.603 rs1121978 chr9:95140351 T/G cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -5.59 -0.45 1.36e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs11626933 1.000 rs6575122 chr14:90753556 A/G cg14092571 chr14:90743983 NA -0.3 -6.13 -0.48 1.06e-8 Gut microbiota (bacterial taxa); TGCT cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg03517284 chr6:25882590 NA -1.01 -11.7 -0.72 9.25e-22 Uric acid levels; TGCT cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs597539 0.652 rs686877 chr11:68637169 G/A cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2982552 0.708 rs1124674 chr6:152080735 A/C cg22157087 chr6:152012887 ESR1 0.2 4.98 0.41 2.07e-6 Bone properties (heel); TGCT trans rs1814175 0.538 rs1684260 chr11:49224231 G/A cg03929089 chr4:120376271 NA 0.71 7.86 0.58 1.61e-12 Height; TGCT cis rs644799 0.526 rs693792 chr11:95622200 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.49 4.84 0.4 3.75e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs924607 0.966 rs1621827 chr5:635074 A/G cg18765565 chr5:669397 TPPP 0.58 6.07 0.48 1.45e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs12549025 0.536 rs9644075 chr8:23359961 C/G cg00472375 chr8:23315376 ENTPD4 0.66 5.2 0.42 8.06e-7 Reticulocyte fraction of red cells; TGCT cis rs909002 0.886 rs11807225 chr1:32083193 G/C cg11573219 chr1:32083031 HCRTR1 -0.49 -6.49 -0.5 1.82e-9 Intelligence (multi-trait analysis); TGCT cis rs9638182 0.725 rs13232120 chr7:72983310 A/T cg14087351 chr7:73037990 MLXIPL -0.64 -4.98 -0.41 2.09e-6 Triglycerides; TGCT cis rs1031261 0.749 rs73922775 chr2:32906594 T/A cg02381751 chr2:32503542 YIPF4 -0.73 -4.47 -0.37 1.72e-5 Hippocampal atrophy; TGCT cis rs1691799 0.899 rs903589 chr12:66745835 C/T cg16791601 chr12:66731901 HELB -0.27 -5.81 -0.46 4.89e-8 White blood cell count (basophil); TGCT cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs10504229 1.000 rs66479724 chr8:58188309 T/G cg21724239 chr8:58056113 NA 0.37 4.95 0.41 2.38e-6 Developmental language disorder (linguistic errors); TGCT cis rs9911578 0.935 rs12948039 chr17:57045184 C/T cg05425664 chr17:57184151 TRIM37 -0.56 -5.42 -0.44 2.99e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.924 rs7546641 chr1:76158035 T/C cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7824557 0.707 rs2572419 chr8:11137820 C/T cg21775007 chr8:11205619 TDH -0.59 -5.69 -0.46 8.5e-8 Retinal vascular caliber; TGCT cis rs7017914 0.905 rs2639899 chr8:71919462 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs778371 0.723 rs737027 chr2:233641083 G/C cg08000102 chr2:233561755 GIGYF2 0.72 8.68 0.61 1.91e-14 Schizophrenia; TGCT cis rs11239930 0.538 rs3011810 chr1:146553628 A/C cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs769267 0.896 rs10410664 chr19:19556651 G/A cg08509172 chr19:19383838 TM6SF2 -0.35 -4.63 -0.38 9.18e-6 Tonsillectomy; TGCT cis rs13191362 0.872 rs67712738 chr6:163245768 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.67 4.66 0.39 8.09e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6840360 1.000 rs1877187 chr4:152605621 C/T cg17479576 chr4:152424074 FAM160A1 -0.46 -4.9 -0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7172809 0.615 rs76499944 chr15:77804814 A/G cg22256960 chr15:77711686 NA -0.5 -4.75 -0.39 5.62e-6 Glucose homeostasis traits; TGCT cis rs314370 0.818 rs13245899 chr7:100497131 A/G cg10426581 chr7:100472382 SRRT 0.96 11.37 0.71 5.95e-21 Resting heart rate; TGCT cis rs3096299 0.719 rs12934708 chr16:89523790 C/T cg08392591 chr16:89556376 ANKRD11 0.6 5.64 0.45 1.09e-7 Multiple myeloma (IgH translocation); TGCT cis rs4372836 0.729 rs67410623 chr2:29057440 G/A cg09522027 chr2:28974177 PPP1CB 0.66 6.77 0.52 4.53e-10 Body mass index; TGCT cis rs3796352 0.667 rs3755805 chr3:52866299 G/A cg27565382 chr3:53032988 SFMBT1 0.49 4.47 0.37 1.75e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1577917 0.771 rs2758844 chr6:86330115 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs6570726 0.620 rs12201226 chr6:145913419 A/T cg13319975 chr6:146136371 FBXO30 -0.68 -6.23 -0.49 6.81e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4888262 0.526 rs7201105 chr16:74590603 A/G cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 7.94e-11 Testicular germ cell tumor; TGCT cis rs2227564 0.649 rs2688626 chr10:75611090 G/A cg19442545 chr10:75533431 FUT11 -0.33 -4.72 -0.39 6.29e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs9926296 0.609 rs4785710 chr16:89796756 C/T cg08627397 chr16:89984028 MC1R 0.31 4.95 0.41 2.33e-6 Vitiligo; TGCT cis rs2404602 0.669 rs12148877 chr15:76919959 T/G cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.07e-6 Blood metabolite levels; TGCT cis rs2463822 0.925 rs74692811 chr11:62156572 G/A cg06239285 chr11:62104954 ASRGL1 -0.92 -6.75 -0.52 5.06e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7818688 0.697 rs74861094 chr8:95981385 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7666738 0.830 rs62321598 chr4:99014237 C/T cg05340658 chr4:99064831 C4orf37 0.47 5.33 0.43 4.51e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs11755334 chr6:146399297 T/C cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg23156509 chr2:114033830 PAX8;LOC440839 -0.32 -4.93 -0.4 2.58e-6 Lymphocyte counts; TGCT cis rs7917772 0.636 rs2486757 chr10:104535145 C/T cg05855489 chr10:104503620 C10orf26 -0.63 -5.05 -0.41 1.54e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4499344 0.805 rs116855540 chr19:33083830 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.74 -6.49 -0.5 1.87e-9 Mean platelet volume; TGCT cis rs6570726 0.935 rs447818 chr6:145868996 C/T cg23711669 chr6:146136114 FBXO30 0.7 6.78 0.52 4.39e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9653442 0.777 rs6732141 chr2:100743492 G/C cg07810366 chr2:100720526 AFF3 -0.47 -7.82 -0.57 1.99e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs12142240 0.698 rs1053627 chr1:46827728 A/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs9467711 0.606 rs67234939 chr6:26530419 A/G cg16898833 chr6:26189333 HIST1H4D 1.04 5.4 0.44 3.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs5771225 0.563 rs1129880 chr22:50694297 A/G cg16473166 chr22:50639996 SELO 0.69 5.69 0.45 8.74e-8 Late-onset Alzheimer's disease; TGCT cis rs6540559 0.611 rs76766079 chr1:209997731 C/T cg22029157 chr1:209979665 IRF6 0.71 5.04 0.41 1.61e-6 Cleft lip with or without cleft palate; TGCT cis rs9549367 0.789 rs3764124 chr13:113897320 C/T cg00898013 chr13:113819073 PROZ -0.4 -5.07 -0.41 1.42e-6 Platelet distribution width; TGCT cis rs6500602 0.826 rs9925719 chr16:4461861 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.44 6.71 0.52 6.09e-10 Schizophrenia; TGCT cis rs11105298 0.891 rs11105312 chr12:89920733 C/T cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4851266 1.000 rs11689201 chr2:100820431 A/G cg07810366 chr2:100720526 AFF3 -0.39 -5.64 -0.45 1.11e-7 Educational attainment; TGCT cis rs7681440 0.904 rs28415623 chr4:90767110 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs12497850 0.864 rs7431857 chr3:48900347 G/A cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs4819052 0.851 rs28616694 chr21:46674786 G/C cg06618935 chr21:46677482 NA -0.37 -5.55 -0.45 1.65e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12477438 0.798 rs6761570 chr2:99577276 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs7772486 0.713 rs1986729 chr6:146194831 G/A cg23711669 chr6:146136114 FBXO30 0.97 11.27 0.71 1.01e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs274567 0.602 rs272853 chr5:131688561 A/G cg24060327 chr5:131705240 SLC22A5 -0.73 -7.94 -0.58 1.01e-12 Blood metabolite levels; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg11905131 chr22:24372483 LOC391322 -1.03 -13.21 -0.76 2.1e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg00684032 chr4:1343700 KIAA1530 0.23 5.01 0.41 1.79e-6 Obesity-related traits; TGCT cis rs739496 0.515 rs66480035 chr12:112052651 T/C cg10833066 chr12:111807467 FAM109A 0.35 5.25 0.43 6.5e-7 Platelet count; TGCT cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT trans rs1005277 0.579 rs1780122 chr10:38529509 C/A cg17830980 chr10:43048298 ZNF37B -0.83 -10.39 -0.68 1.4e-18 Extrinsic epigenetic age acceleration; TGCT cis rs1215050 0.740 rs1648568 chr4:98957619 A/G cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.12e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7824557 0.547 rs2409745 chr8:11076635 G/T cg27411982 chr8:10470053 RP1L1 0.22 4.82 0.4 4.13e-6 Retinal vascular caliber; TGCT cis rs10892173 0.566 rs10892174 chr11:117672565 A/C cg21014159 chr11:117668035 DSCAML1 0.61 5.86 0.47 3.96e-8 Myopia; TGCT cis rs1865760 0.663 rs9379815 chr6:25980116 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.7 6.91 0.53 2.26e-10 Height; TGCT cis rs7264396 0.676 rs1341603 chr20:34556216 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg10295955 chr4:187884368 NA -1.0 -14.26 -0.79 6.69e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs250677 0.917 rs36066 chr5:148419771 A/G cg18129178 chr5:148520854 ABLIM3 -0.4 -5.58 -0.45 1.42e-7 Breast cancer; TGCT cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.49 -0.37 1.58e-5 Bipolar disorder; TGCT cis rs7731657 0.537 rs9327578 chr5:130181064 C/T cg08523029 chr5:130500466 HINT1 -0.59 -4.95 -0.41 2.41e-6 Fasting plasma glucose; TGCT cis rs10540 1.000 rs12801271 chr11:508720 C/T cg03934478 chr11:495069 RNH1 0.32 4.83 0.4 3.94e-6 Body mass index; TGCT cis rs2295359 0.824 rs4655679 chr1:67599657 A/G cg03340356 chr1:67600835 NA -0.41 -4.95 -0.41 2.37e-6 Psoriasis; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg12405048 chr12:112074086 NA 0.67 6.8 0.52 3.88e-10 Gambling; TGCT cis rs78456975 1.000 rs13414537 chr2:1556330 C/T cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs11249608 0.548 rs13161528 chr5:178452958 C/G cg23951258 chr5:178450506 ZNF879 0.45 4.61 0.38 9.7e-6 Pubertal anthropometrics; TGCT cis rs28595532 0.764 rs115298416 chr4:119565383 C/T cg11846333 chr4:119757529 SEC24D 0.96 4.75 0.39 5.58e-6 Cannabis dependence symptom count; TGCT cis rs910316 1.000 rs12889472 chr14:75543979 A/G cg11812906 chr14:75593930 NEK9 0.74 7.19 0.54 5.49e-11 Height; TGCT cis rs9457247 1.000 rs415890 chr6:167406633 C/G cg23791538 chr6:167370224 RNASET2 0.51 5.06 0.41 1.45e-6 Crohn's disease; TGCT cis rs9311474 0.629 rs13081028 chr3:52555316 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.53 5.06 0.41 1.47e-6 Electroencephalogram traits; TGCT cis rs35306767 0.903 rs35968821 chr10:910225 A/G cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs2228479 0.850 rs11640209 chr16:89807828 C/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs6459788 0.934 rs10237947 chr7:157258109 G/T cg03453431 chr7:157225567 NA 0.34 5.29 0.43 5.43e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs559555 0.626 rs499362 chr2:31811572 A/C cg02381751 chr2:32503542 YIPF4 0.46 4.46 0.37 1.8e-5 Blood metabolite ratios;Blood metabolite levels; TGCT cis rs74233809 1.000 rs12221064 chr10:104677126 C/T cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs1005277 0.557 rs176887 chr10:38406094 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg11301795 chr4:187892539 NA -0.34 -5.13 -0.42 1.08e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7917772 0.502 rs2296584 chr10:104244323 T/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4665630 0.708 rs4078753 chr2:23896727 C/T cg08063864 chr2:24346004 PFN4;LOC375190 -1.0 -4.97 -0.41 2.17e-6 Hypertension; TGCT cis rs13242816 1.000 rs55833477 chr7:116110375 C/G cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs2016266 0.819 rs10747662 chr12:53669821 A/T cg16917193 chr12:54089295 NA 0.66 4.96 0.41 2.22e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs769267 0.965 rs7254230 chr19:19434350 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg04267008 chr7:1944627 MAD1L1 -0.41 -5.4 -0.44 3.34e-7 Bipolar disorder and schizophrenia; TGCT cis rs2594989 0.943 rs901865 chr3:11300707 T/C cg00170343 chr3:11313890 ATG7 0.65 4.73 0.39 6.09e-6 Circulating chemerin levels; TGCT cis rs4901869 0.966 rs60800733 chr14:59337778 A/G cg02291164 chr14:59296302 NA 0.25 4.73 0.39 5.99e-6 Panic disorder; TGCT cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1008375 1.000 rs3933453 chr4:17636319 A/C cg18681998 chr4:17616180 MED28 1.02 11.55 0.72 2.14e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1008375 0.966 rs6832962 chr4:17652133 T/C cg16339924 chr4:17578868 LAP3 0.66 5.52 0.44 1.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs9486719 0.947 rs11755945 chr6:96908038 G/C cg18709589 chr6:96969512 KIAA0776 -0.68 -5.05 -0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs3812831 0.661 rs2987458 chr13:114919835 A/G cg06611532 chr13:114900021 NA 0.34 6.02 0.48 1.82e-8 Schizophrenia; TGCT cis rs78707713 0.512 rs12772559 chr10:71184356 C/G cg12610070 chr10:71211762 TSPAN15 -0.58 -6.53 -0.51 1.49e-9 Venous thromboembolism; TGCT cis rs7246657 0.722 rs4802029 chr19:38055612 A/T cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs2535633 0.588 rs2564930 chr3:53017307 T/C cg10802521 chr3:52805072 NEK4 0.55 5.88 0.47 3.48e-8 Body mass index; TGCT cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 5.27 0.43 5.81e-7 Electroencephalogram traits; TGCT cis rs6815814 1.000 rs6815814 chr4:38816338 A/C cg02016764 chr4:38805732 TLR1 -0.29 -4.83 -0.4 3.95e-6 Breast cancer; TGCT cis rs61990749 0.544 rs11628888 chr14:78161506 T/C cg02301378 chr14:78227641 SNW1;C14orf178 -0.6 -4.44 -0.37 2.01e-5 Fibroblast growth factor basic levels; TGCT cis rs6684514 0.922 rs11264475 chr1:156306918 G/A cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4919694 0.572 rs4917995 chr10:104845443 A/T cg04362960 chr10:104952993 NT5C2 -0.99 -6.74 -0.52 5.39e-10 Arsenic metabolism; TGCT cis rs1670533 1.000 rs2014318 chr4:1068778 C/T cg20887711 chr4:1340912 KIAA1530 -0.69 -5.54 -0.45 1.72e-7 Recombination rate (females); TGCT cis rs28595532 0.623 rs34082100 chr4:119220563 C/T cg21605333 chr4:119757512 SEC24D 0.78 4.84 0.4 3.75e-6 Cannabis dependence symptom count; TGCT cis rs7552404 0.924 rs2275378 chr1:76198436 T/C cg22875332 chr1:76189707 ACADM 0.76 9.33 0.64 5.34e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17125944 0.615 rs12589020 chr14:53312002 C/T cg00686598 chr14:53173677 PSMC6 0.86 4.54 0.38 1.32e-5 Alzheimer's disease (late onset); TGCT cis rs7666738 0.688 rs4632667 chr4:98748299 A/G cg17366294 chr4:99064904 C4orf37 0.69 5.38 0.43 3.62e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4713118 0.955 rs9468204 chr6:27688809 C/T cg10876282 chr6:28092338 ZSCAN16 0.5 4.67 0.39 7.86e-6 Parkinson's disease; TGCT cis rs2019137 0.905 rs2276561 chr2:113956371 G/C cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs4727027 0.865 rs62505077 chr7:148849656 T/A cg23583168 chr7:148888333 NA -0.77 -10.1 -0.67 7.35e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2153535 0.504 rs5001323 chr6:8451605 C/T cg07606381 chr6:8435919 SLC35B3 0.53 5.03 0.41 1.71e-6 Motion sickness; TGCT cis rs6882076 1.000 rs12517431 chr5:156392248 C/T cg12943317 chr5:156479607 HAVCR1 -0.31 -6.09 -0.48 1.31e-8 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs4689388 0.819 rs12649341 chr4:6294759 G/A cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7824557 0.569 rs35418978 chr8:11186453 T/C cg21775007 chr8:11205619 TDH 0.69 6.62 0.51 9.52e-10 Retinal vascular caliber; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg02953382 chr22:24373134 LOC391322 -0.79 -8.27 -0.6 1.72e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9443645 0.835 rs1044309 chr6:79646575 A/G cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs2658782 0.547 rs3020054 chr11:93055556 C/T cg15737290 chr11:93063684 CCDC67 1.11 11.61 0.72 1.5e-21 Pulmonary function decline; TGCT cis rs9534288 0.742 rs1022952 chr13:46649348 C/T cg15192986 chr13:46630673 CPB2 0.52 6.39 0.5 2.97e-9 Blood protein levels; TGCT cis rs763121 0.815 rs12168758 chr22:38997269 C/G cg06022373 chr22:39101656 GTPBP1 0.73 7.02 0.53 1.26e-10 Menopause (age at onset); TGCT cis rs9486715 1.000 rs6902835 chr6:97063005 C/G cg06623918 chr6:96969491 KIAA0776 -1.07 -13.0 -0.76 6.68e-25 Headache; TGCT cis rs9818758 0.607 rs61729488 chr3:49067904 T/C cg07636037 chr3:49044803 WDR6 -1.0 -4.82 -0.4 4.15e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs911263 0.603 rs11158729 chr14:68776060 T/C cg18825221 chr14:68749962 RAD51L1 0.22 4.48 0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs950027 0.620 rs872192 chr15:45614502 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 6.08 0.48 1.35e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs9810089 0.843 rs650326 chr3:136037707 G/A cg12473912 chr3:136751656 NA 0.36 5.15 0.42 9.88e-7 Gestational age at birth (child effect); TGCT cis rs7267979 1.000 rs6076345 chr20:25381895 T/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5769765 0.908 rs138866 chr22:50205903 A/G cg22709217 chr22:50311962 ALG12;CRELD2 0.98 10.24 0.68 3.32e-18 Schizophrenia; TGCT cis rs611744 0.934 rs604698 chr8:109238721 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs939658 0.967 rs7171067 chr15:79452727 G/T cg17916960 chr15:79447300 NA 0.52 8.15 0.59 3.36e-13 Refractive error; TGCT cis rs7255045 0.788 rs8110185 chr19:12959827 T/A cg06537894 chr19:12978706 MAST1 -0.49 -4.48 -0.37 1.69e-5 Mean corpuscular volume; TGCT cis rs644799 0.965 rs11021310 chr11:95502106 A/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.82 0.7 1.31e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2456568 0.802 rs10831139 chr11:93640537 G/A cg17595323 chr11:93583763 C11orf90 -0.46 -6.24 -0.49 6.46e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2629540 0.765 rs7097177 chr10:126539839 A/G cg08799069 chr10:126477246 METTL10 -0.28 -4.58 -0.38 1.12e-5 Cocaine dependence; TGCT cis rs2688608 0.618 rs28718766 chr10:75489844 C/A cg23231163 chr10:75533350 FUT11 -0.29 -4.87 -0.4 3.37e-6 Inflammatory bowel disease; TGCT trans rs2727020 0.729 rs10839283 chr11:49490943 T/C cg03929089 chr4:120376271 NA 0.73 8.36 0.6 1.08e-13 Coronary artery disease; TGCT cis rs116095464 0.558 rs10067021 chr5:221490 C/T cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs146201400 1 rs146201400 chr1:26645955 G/GA cg04990556 chr1:26633338 UBXN11 -0.62 -5.46 -0.44 2.45e-7 Monocyte percentage of white cells; TGCT cis rs10751667 0.666 rs7123912 chr11:963936 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT cis rs7552404 0.727 rs61770533 chr1:76306490 C/G cg03433033 chr1:76189801 ACADM 0.65 6.73 0.52 5.56e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs35000415 0.938 rs35234849 chr7:128648953 T/C cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs7666738 0.830 rs4699590 chr4:98974030 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7572733 0.534 rs700664 chr2:198671145 C/T cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg10117171 chr1:25599238 RHD -0.36 -5.89 -0.47 3.47e-8 Erythrocyte sedimentation rate; TGCT cis rs4654899 1.000 rs61117207 chr1:21394374 A/C cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT trans rs7618501 0.521 rs11130222 chr3:49901060 A/T cg21665057 chr3:196295764 WDR53;FBXO45 0.82 8.47 0.61 6.11e-14 Intelligence (multi-trait analysis); TGCT trans rs11722228 0.521 rs12501336 chr4:10137351 G/A cg26043149 chr18:55253948 FECH 1.09 13.01 0.76 6.33e-25 Gout;Urate levels;Serum uric acid levels; TGCT cis rs9796 0.870 rs7162992 chr15:41290861 T/C cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.42 -0.44 3.01e-7 Menopause (age at onset); TGCT cis rs7944584 1.000 rs7944584 chr11:47336320 A/T cg20307385 chr11:47447363 PSMC3 0.78 7.41 0.55 1.75e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs694739 0.964 rs2510066 chr11:64052447 C/T cg02228329 chr11:64053129 BAD;GPR137 0.75 7.5 0.56 1.08e-11 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs2836950 0.545 rs8132143 chr21:40584258 A/T cg17971929 chr21:40555470 PSMG1 -0.52 -4.69 -0.39 7.17e-6 Menarche (age at onset); TGCT cis rs7772486 0.719 rs702307 chr6:145993454 C/G cg23711669 chr6:146136114 FBXO30 -0.93 -10.56 -0.69 5.5e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs2692947 0.770 rs11689832 chr2:96554851 A/C cg13655245 chr2:97463316 CNNM4 0.15 4.51 0.38 1.51e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs6671200 1.000 rs259359 chr1:95709039 A/G cg03123541 chr1:95699097 RWDD3 -0.87 -6.13 -0.48 1.09e-8 Stearic acid (18:0) levels; TGCT cis rs4845570 0.764 rs12122917 chr1:151716712 C/A cg07092448 chr1:151763213 TDRKH -1.03 -7.53 -0.56 8.99e-12 Coronary artery disease; TGCT cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg03452623 chr4:187889614 NA -0.36 -5.3 -0.43 5.01e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs79349575 0.749 rs2270574 chr17:47022270 C/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs7267979 0.932 rs417110 chr20:25458297 T/C cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg10108389 chr3:44770937 ZNF501 -0.48 -4.96 -0.41 2.31e-6 Depressive symptoms; TGCT cis rs7216064 1.000 rs7209675 chr17:65831258 A/T cg12091567 chr17:66097778 LOC651250 -0.9 -6.83 -0.52 3.43e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9653442 0.675 rs7605430 chr2:100647552 C/G cg07810366 chr2:100720526 AFF3 0.39 6.44 0.5 2.42e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs72945132 1.000 rs56913804 chr11:70114673 G/A cg00319359 chr11:70116639 PPFIA1 0.98 7.07 0.54 9.95e-11 Coronary artery disease; TGCT cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg09222892 chr1:25734099 RHCE -0.44 -7.02 -0.53 1.3100000000000001e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs7666738 0.830 rs1405767 chr4:98965295 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg10802521 chr3:52805072 NEK4 -0.65 -7.63 -0.57 5.37e-12 Electroencephalogram traits; TGCT cis rs2033711 0.936 rs3794968 chr19:58986799 G/C cg04608855 chr19:58913158 NA 0.54 5.07 0.41 1.42e-6 Uric acid clearance; TGCT cis rs6940638 0.615 rs9393801 chr6:27242681 A/G cg05738196 chr6:26577821 NA -0.53 -4.76 -0.39 5.38e-6 Intelligence (multi-trait analysis); TGCT cis rs3796352 0.892 rs3821872 chr3:53080555 C/G cg15956490 chr3:53032818 SFMBT1 -0.53 -6.29 -0.49 4.97e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg25767906 chr1:53392781 SCP2 -0.52 -6.19 -0.49 8.06e-9 Monocyte count; TGCT cis rs6831352 0.840 rs17817868 chr4:100060623 C/T cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs709400 0.520 rs28583452 chr14:103938664 C/A cg12935359 chr14:103987150 CKB -0.36 -5.55 -0.45 1.67e-7 Body mass index; TGCT cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs6582630 0.519 rs11182457 chr12:38538331 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.18 0.42 8.78e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs13082711 0.689 rs34641383 chr3:27320210 G/A cg02860705 chr3:27208620 NA 0.58 8.58 0.61 3.32e-14 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2836974 0.965 rs34578707 chr21:40675167 G/A cg06238570 chr21:40685208 BRWD1 0.59 5.29 0.43 5.26e-7 Cognitive function; TGCT cis rs9914544 0.545 rs12937933 chr17:18770283 C/G cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs6121246 0.909 rs1994250 chr20:30287494 A/G cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg24675658 chr1:53192096 ZYG11B -0.74 -9.03 -0.63 2.84e-15 Monocyte count; TGCT cis rs9952991 0.941 rs2014857 chr18:12774326 C/T cg24737193 chr18:12778029 NA 0.53 5.93 0.47 2.8e-8 Inflammatory skin disease; TGCT cis rs6840360 0.571 rs1978955 chr4:152509509 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs2338224 1.000 rs10068109 chr5:71744199 C/T cg01187920 chr5:71015162 CARTPT 0.5 4.47 0.37 1.74e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg11494091 chr17:61959527 GH2 0.43 7.34 0.55 2.45e-11 Height; TGCT cis rs902774 0.515 rs2363635 chr12:53354622 T/C cg05393297 chr12:53359155 NA -0.75 -8.33 -0.6 1.27e-13 Prostate cancer; TGCT cis rs727563 0.520 rs132773 chr22:42031768 T/A cg17554472 chr22:41940697 POLR3H 0.5 5.26 0.43 6.02e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2153535 0.541 rs6938688 chr6:8521629 G/T cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9660992 0.573 rs12144980 chr1:205185104 C/T cg00857998 chr1:205179979 DSTYK 0.51 4.75 0.39 5.63e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs9291683 0.620 rs11722946 chr4:10125990 A/G cg11266682 chr4:10021025 SLC2A9 -0.43 -5.15 -0.42 9.84e-7 Bone mineral density; TGCT cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 9.49 0.65 2.23e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs9929218 0.953 rs12920562 chr16:68737512 C/T cg01251360 chr16:68772225 CDH1 0.3 4.81 0.4 4.35e-6 Colorectal cancer; TGCT cis rs7582180 0.606 rs11684004 chr2:100954783 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs7937682 1.000 rs7121011 chr11:111568681 C/T cg09085632 chr11:111637200 PPP2R1B 1.04 9.55 0.65 1.58e-16 Primary sclerosing cholangitis; TGCT cis rs4455778 0.628 rs11185623 chr7:49027187 T/C cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs2688608 0.592 rs10762559 chr10:75486453 G/C cg04320760 chr10:75533139 FUT11 -0.4 -6.24 -0.49 6.28e-9 Inflammatory bowel disease; TGCT cis rs4665809 0.941 rs6735145 chr2:26270302 T/C cg22920501 chr2:26401640 FAM59B -0.7 -6.05 -0.48 1.59e-8 Gut microbiome composition (summer); TGCT cis rs2019216 0.500 rs6565385 chr17:21897646 C/A cg22648282 chr17:21454238 C17orf51 -0.56 -5.51 -0.44 1.97e-7 Pelvic organ prolapse; TGCT cis rs7586879 0.616 rs6545809 chr2:25126715 C/T cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs6570726 0.764 rs9399553 chr6:145873664 A/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs7618501 0.633 rs9853222 chr3:50022926 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.9 0.66 2.18e-17 Intelligence (multi-trait analysis); TGCT cis rs1372520 0.627 rs2737025 chr4:90719192 A/G cg15133208 chr4:90757351 SNCA -0.52 -6.07 -0.48 1.44e-8 Neuroticism; TGCT cis rs56104184 0.723 rs1058483 chr19:49407660 G/A cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs597539 0.652 rs602805 chr11:68662076 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.04 0.59 5.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs290268 0.874 rs772407 chr9:93560850 A/C cg02608019 chr9:93564028 SYK 0.44 4.44 0.37 1.94e-5 Platelet count; TGCT cis rs10256972 0.680 rs7784708 chr7:1003049 A/G cg07930192 chr7:1003750 NA 0.3 4.72 0.39 6.33e-6 Longevity;Endometriosis; TGCT cis rs377070 0.816 rs309406 chr4:123618707 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.44 4.85 0.4 3.66e-6 Mosquito bite size; TGCT cis rs453301 0.658 rs3855900 chr8:8901921 A/G cg06636001 chr8:8085503 FLJ10661 -0.68 -5.5 -0.44 2.1e-7 Joint mobility (Beighton score); TGCT cis rs10883723 0.810 rs10748823 chr10:104274465 C/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs8100891 0.734 rs4804990 chr19:32837429 C/G cg16662424 chr19:32837316 ZNF507 -0.46 -5.58 -0.45 1.44e-7 Neuroticism; TGCT cis rs9300255 0.602 rs1790098 chr12:123655481 A/C cg00376283 chr12:123451042 ABCB9 0.66 4.85 0.4 3.59e-6 Neutrophil percentage of white cells; TGCT cis rs11696501 0.694 rs6073825 chr20:44258217 T/C cg11783356 chr20:44313418 WFDC10B -0.33 -4.66 -0.39 7.91e-6 Brain structure; TGCT cis rs34779708 0.931 rs35317849 chr10:35285721 C/A cg04310649 chr10:35416472 CREM -0.51 -4.55 -0.38 1.24e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs9443189 0.527 rs775059 chr6:76370130 G/T cg01950844 chr6:76311363 SENP6 1.0 6.24 0.49 6.35e-9 Prostate cancer; TGCT cis rs807669 0.807 rs807431 chr22:19242361 G/A cg02655711 chr22:19163373 SLC25A1 0.34 7.5 0.56 1.09e-11 Metabolite levels; TGCT cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17376456 0.504 rs7702649 chr5:93065149 C/A cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT trans rs1814175 0.817 rs10128730 chr11:50023369 G/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs7552404 0.727 rs2172507 chr1:76331320 A/G cg03433033 chr1:76189801 ACADM -0.6 -6.01 -0.48 1.9e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs832540 0.966 rs252923 chr5:56205662 T/G cg24531977 chr5:56204891 C5orf35 -0.55 -5.75 -0.46 6.44e-8 Coronary artery disease; TGCT trans rs7618501 0.572 rs7428430 chr3:50174184 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.85 -9.03 -0.63 2.77e-15 Intelligence (multi-trait analysis); TGCT cis rs1420338 0.967 rs4720151 chr7:34160523 G/A cg01275685 chr7:34179230 BMPER -0.25 -4.56 -0.38 1.23e-5 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2915864 0.628 rs6580216 chr5:141433075 C/T cg19884223 chr5:140554610 PCDHB7 -0.64 -4.45 -0.37 1.88e-5 Facial morphology (factor 20); TGCT cis rs9467773 1.000 rs1884949 chr6:26568067 G/A cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs587847 0.767 rs4924155 chr15:37666501 T/C cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs1153858 1.000 rs66939267 chr15:45676902 T/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs11190604 0.945 rs2495735 chr10:102338609 G/A cg16342193 chr10:102329863 NA -0.4 -5.08 -0.42 1.32e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7927592 0.546 rs599083 chr11:68192346 T/G cg16797656 chr11:68205561 LRP5 0.29 4.97 0.41 2.16e-6 Total body bone mineral density; TGCT cis rs3734905 1.000 rs2075978 chr6:169812588 A/G cg05229362 chr6:169789120 NA 0.48 4.44 0.37 1.94e-5 HIV-1 control; TGCT cis rs909341 0.678 rs2738778 chr20:62291830 C/T cg03999872 chr20:62272968 STMN3 -0.36 -4.71 -0.39 6.53e-6 Atopic dermatitis; TGCT cis rs7586879 0.719 rs7565468 chr2:25130092 C/T cg01884057 chr2:25150051 NA 0.27 4.83 0.4 3.87e-6 Body mass index; TGCT cis rs916888 0.610 rs199436 chr17:44789285 C/T cg15921436 chr17:44337874 NA -0.41 -6.58 -0.51 1.21e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2463822 1.000 rs2513747 chr11:62098735 T/C cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs12142240 0.698 rs112089006 chr1:46812360 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.79 -0.4 4.68e-6 Menopause (age at onset); TGCT trans rs6695400 0.610 rs9433784 chr1:101784340 A/C cg17848389 chr13:114886717 RASA3 -0.37 -7.12 -0.54 7.76e-11 Initial pursuit acceleration; TGCT cis rs36051895 0.664 rs3780374 chr9:5099677 G/A cg02405213 chr9:5042618 JAK2 -0.71 -9.43 -0.65 3.07e-16 Pediatric autoimmune diseases; TGCT cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs7091068 0.671 rs514120 chr10:95404400 G/A cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs2404602 0.569 rs2469249 chr15:76772062 C/T cg26408565 chr15:76604113 ETFA 0.4 4.56 0.38 1.19e-5 Blood metabolite levels; TGCT cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 9.11 0.63 1.81e-15 Platelet count; TGCT cis rs4663969 0.733 rs6741669 chr2:234653192 A/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.61 -0.38 9.83e-6 Total bilirubin levels in HIV-1 infection; TGCT trans rs804280 0.509 rs4841639 chr8:11796093 A/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Myopia (pathological); TGCT cis rs4665809 0.938 rs6742226 chr2:26342537 A/G cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs769267 0.965 rs735273 chr19:19385411 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs7917772 0.582 rs10786687 chr10:104336994 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13191362 1.000 rs73035021 chr6:163000716 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.830 rs1967980 chr4:98966426 C/G cg17366294 chr4:99064904 C4orf37 0.74 7.54 0.56 8.74e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg03806693 chr22:41940476 POLR3H -1.01 -11.18 -0.71 1.71e-20 Vitiligo; TGCT cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg19729930 chr2:74357872 NA 0.57 6.9 0.53 2.39e-10 Gestational age at birth (maternal effect); TGCT cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.14e-10 Bipolar disorder; TGCT cis rs11098499 0.697 rs4373140 chr4:120307698 A/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs13191362 1.000 rs1333963 chr6:163192571 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.11 8.17 0.59 2.98e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg06558623 chr16:89946397 TCF25 0.56 7.51 0.56 1.04e-11 Skin colour saturation; TGCT cis rs4665809 0.878 rs6720312 chr2:26364934 A/G cg04944784 chr2:26401820 FAM59B 0.71 6.24 0.49 6.24e-9 Gut microbiome composition (summer); TGCT cis rs9372498 0.536 rs9489447 chr6:118900846 G/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.04 -0.41 1.59e-6 Diastolic blood pressure; TGCT trans rs7618501 0.572 rs4688756 chr3:50040194 T/A cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.41 0.65 3.39e-16 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg11644478 chr21:40555479 PSMG1 1.01 10.47 0.69 8.99e-19 Cognitive function; TGCT cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg11502198 chr6:26597334 ABT1 0.54 4.95 0.41 2.42e-6 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.524 rs7835318 chr8:10953874 G/A cg27411982 chr8:10470053 RP1L1 -0.22 -4.81 -0.4 4.3e-6 Retinal vascular caliber; TGCT cis rs9372498 0.706 rs9489396 chr6:118761703 A/C cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs6988636 0.818 rs10111810 chr8:124169565 G/A cg27053337 chr8:124217698 FAM83A 0.67 4.77 0.39 5.15e-6 Urinary uromodulin levels; TGCT cis rs7786808 0.504 rs10949725 chr7:158196003 C/T cg01191920 chr7:158217561 PTPRN2 0.36 5.27 0.43 5.86e-7 Obesity-related traits; TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT trans rs6089829 0.962 rs3746749 chr20:61667333 T/C cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.909 rs6119725 chr20:30385557 G/T cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7412746 0.587 rs11204722 chr1:150730184 A/C cg09365446 chr1:150670422 GOLPH3L -0.33 -4.84 -0.4 3.75e-6 Melanoma; TGCT cis rs9807989 0.507 rs11465721 chr2:103063240 T/G cg03938978 chr2:103052716 IL18RAP 0.27 5.4 0.44 3.21e-7 Asthma; TGCT cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs7666738 0.830 rs3852123 chr4:98697586 A/G cg05340658 chr4:99064831 C4orf37 0.52 6.13 0.48 1.06e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 1.000 rs72882079 chr6:66973878 T/C cg07460842 chr6:66804631 NA 0.81 7.16 0.54 6.31e-11 Exhaled nitric oxide output; TGCT cis rs6121246 0.529 rs6060291 chr20:30198043 T/G cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg06618935 chr21:46677482 NA -0.37 -5.83 -0.46 4.48e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6545883 0.868 rs7608483 chr2:61836235 A/C cg15711740 chr2:61764176 XPO1 -0.59 -5.52 -0.44 1.9e-7 Tuberculosis; TGCT cis rs939574 1.000 rs11689596 chr2:220093423 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.06 -6.52 -0.51 1.6e-9 Platelet distribution width; TGCT cis rs10791097 0.739 rs11222358 chr11:130730497 G/A cg12179176 chr11:130786555 SNX19 0.73 8.6 0.61 2.98e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12477438 0.501 rs13008171 chr2:99743419 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs477895 0.713 rs12575642 chr11:63979643 G/T cg04317338 chr11:64019027 PLCB3 0.81 7.03 0.53 1.23e-10 Mean platelet volume; TGCT cis rs2075371 0.637 rs2544165 chr7:133920443 A/G cg11752832 chr7:134001865 SLC35B4 -0.64 -5.68 -0.45 9.07e-8 Mean platelet volume; TGCT cis rs7100689 0.646 rs1290317 chr10:82062531 C/A cg01528321 chr10:82214614 TSPAN14 0.75 7.46 0.56 1.32e-11 Post bronchodilator FEV1; TGCT cis rs727505 0.954 rs66871687 chr7:124670475 A/G cg23710748 chr7:124431027 NA -0.27 -4.62 -0.38 9.56e-6 Lewy body disease; TGCT cis rs10193935 0.901 rs10179237 chr2:42515501 C/T cg27598129 chr2:42591480 NA -0.39 -5.37 -0.43 3.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4468007 0.550 rs4837904 chr9:124620480 T/C cg01549227 chr9:124980074 LHX6 -0.3 -4.55 -0.38 1.24e-5 Educational attainment; TGCT cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs12142240 0.698 rs6695043 chr1:46844530 A/G cg14993813 chr1:46806288 NSUN4 0.61 5.01 0.41 1.83e-6 Menopause (age at onset); TGCT cis rs7572733 0.534 rs700682 chr2:198712310 C/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg13695892 chr22:41940480 POLR3H -0.9 -8.66 -0.61 2.17e-14 Vitiligo; TGCT cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs12291225 0.679 rs10832240 chr11:14304744 C/T cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.19e-8 Sense of smell; TGCT cis rs593982 0.764 rs55796623 chr11:65411714 G/A cg08755490 chr11:65554678 OVOL1 -1.14 -6.29 -0.49 4.98e-9 Atopic dermatitis; TGCT cis rs34734847 1.000 rs56273049 chr12:121156041 A/T cg21892295 chr12:121157589 UNC119B -0.24 -5.71 -0.46 7.99e-8 Mean corpuscular volume; TGCT cis rs2730245 0.510 rs2788471 chr7:158649786 G/T cg24397884 chr7:158709396 WDR60 0.35 4.44 0.37 2e-5 Height; TGCT trans rs7618501 0.633 rs7621026 chr3:49975334 A/G cg21659725 chr3:3221576 CRBN 0.76 9.03 0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs6964587 0.934 rs2961019 chr7:91572749 T/G cg17063962 chr7:91808500 NA -0.88 -9.17 -0.64 1.26e-15 Breast cancer; TGCT cis rs7178572 1.000 rs8024485 chr15:77718368 C/A cg15453836 chr15:77711506 NA -0.4 -4.56 -0.38 1.22e-5 Type 2 diabetes; TGCT cis rs9341808 0.683 rs7771449 chr6:80919977 C/T cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs2204008 0.774 rs8186954 chr12:38318566 C/A cg26384229 chr12:38710491 ALG10B 0.79 6.97 0.53 1.67e-10 Bladder cancer; TGCT cis rs1865760 0.532 rs9295687 chr6:26082710 T/C cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs950169 0.580 rs17598114 chr15:85171317 C/T cg17173187 chr15:85201210 NMB 0.61 6.95 0.53 1.84e-10 Schizophrenia; TGCT cis rs68170813 0.641 rs79434636 chr7:107105656 A/C cg02696742 chr7:106810147 HBP1 -0.63 -4.92 -0.4 2.68e-6 Coronary artery disease; TGCT cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg11494091 chr17:61959527 GH2 0.43 7.51 0.56 9.88e-12 Height; TGCT cis rs8016982 0.657 rs8021125 chr14:81704787 C/T cg01989461 chr14:81687754 GTF2A1 -0.8 -7.86 -0.58 1.61e-12 Schizophrenia; TGCT cis rs12541335 0.639 rs3923433 chr8:22169798 A/T cg18135555 chr8:22132992 PIWIL2 0.3 6.14 0.48 1.02e-8 Hypertriglyceridemia; TGCT cis rs981844 1.000 rs2251639 chr4:154656410 T/C cg14289246 chr4:154710475 SFRP2 1.04 8.19 0.59 2.74e-13 Response to statins (LDL cholesterol change); TGCT cis rs11887277 0.707 rs4513249 chr2:27058451 G/T cg14949065 chr2:27373128 TCF23 0.19 4.49 0.37 1.62e-5 Obesity-related traits; TGCT cis rs10782582 0.593 rs11163904 chr1:76121208 A/G cg03433033 chr1:76189801 ACADM 0.62 7.18 0.54 5.71e-11 Daytime sleep phenotypes; TGCT cis rs4746818 1.000 rs10762263 chr10:70970178 A/G cg04149295 chr10:70884716 VPS26A 0.8 5.39 0.44 3.38e-7 Left atrial antero-posterior diameter; TGCT cis rs8177253 1.000 rs8177271 chr3:133482230 G/A cg01448562 chr3:133502909 NA -0.33 -6.58 -0.51 1.16e-9 Iron status biomarkers; TGCT cis rs2361718 0.500 rs8068856 chr17:78100731 A/G cg21238619 chr17:78079768 GAA -0.37 -4.65 -0.39 8.52e-6 Yeast infection; TGCT cis rs2290416 0.688 rs34892354 chr8:144690648 G/C cg08017634 chr8:144659831 NAPRT1 0.51 4.68 0.39 7.36e-6 Attention deficit hyperactivity disorder; TGCT cis rs10927875 0.631 rs28579893 chr1:16347534 A/G cg21385522 chr1:16154831 NA 0.61 6.27 0.49 5.37e-9 Dilated cardiomyopathy; TGCT cis rs7586879 0.616 rs6726199 chr2:25126328 G/C cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs4252435 0.614 rs73460471 chr7:142600094 A/G cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs4455778 0.724 rs10227744 chr7:49007522 A/G cg26309511 chr7:48887640 NA -0.49 -5.87 -0.47 3.75e-8 Lung cancer in never smokers; TGCT cis rs6750047 0.585 rs4670234 chr2:38272477 C/T cg07380506 chr2:38303506 CYP1B1 0.59 5.36 0.43 3.84e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs36051895 0.587 rs11999802 chr9:5189773 T/G cg02405213 chr9:5042618 JAK2 -0.66 -7.81 -0.57 2.13e-12 Pediatric autoimmune diseases; TGCT cis rs896854 0.846 rs13254283 chr8:95914103 G/T cg16049864 chr8:95962084 TP53INP1 -0.71 -9.83 -0.66 3.32e-17 Type 2 diabetes; TGCT cis rs806215 0.547 rs10487497 chr7:127400667 C/T cg11539674 chr7:127291444 SND1 0.36 4.76 0.39 5.32e-6 Type 2 diabetes; TGCT cis rs2072499 0.868 rs2758600 chr1:156195205 C/T cg25208724 chr1:156163844 SLC25A44 1.11 12.68 0.75 3.79e-24 Testicular germ cell tumor; TGCT cis rs7264396 0.747 rs2425151 chr20:34394541 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.25 -0.43 6.36e-7 Total cholesterol levels; TGCT cis rs2180341 1.000 rs6937287 chr6:127645719 T/A cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs6555855 0.868 rs1592818 chr5:168741524 G/T cg26492514 chr5:168728236 SLIT3 -0.28 -4.48 -0.37 1.66e-5 Menarche (age at onset); TGCT cis rs66887589 0.592 rs11731571 chr4:120221185 G/A cg24670566 chr4:120433619 PDE5A 0.21 4.52 0.38 1.43e-5 Diastolic blood pressure; TGCT cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs11025559 1.000 rs11025559 chr11:20443875 A/G cg19653624 chr11:20408972 PRMT3 0.61 4.72 0.39 6.3e-6 Pursuit maintenance gain; TGCT cis rs8064299 0.597 rs7210318 chr17:72783385 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.88 9.97 0.67 1.49e-17 Monocyte count; TGCT cis rs2204008 0.605 rs4608149 chr12:38132057 G/C cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs8014204 0.753 rs6574199 chr14:75356103 T/C cg06637938 chr14:75390232 RPS6KL1 -0.75 -7.25 -0.55 4e-11 Caffeine consumption; TGCT cis rs2046867 0.818 rs2208 chr3:72871773 A/G cg25664220 chr3:72788482 NA 0.52 6.66 0.51 8.01e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs394563 0.726 rs6922130 chr6:149672375 C/G cg11245181 chr6:149772854 ZC3H12D 0.28 4.6 0.38 1.01e-5 Dupuytren's disease; TGCT cis rs11673344 0.542 rs1667380 chr19:37492750 C/T cg08039142 chr19:36980659 ZNF566 0.58 5.61 0.45 1.25e-7 Obesity-related traits; TGCT cis rs2964802 0.505 rs1438714 chr5:10811422 G/A cg14521931 chr5:10832172 NA -0.28 -4.59 -0.38 1.09e-5 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs4319547 0.760 rs61954973 chr12:123074168 T/C cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.38 -0.44 3.5e-7 Body mass index; TGCT cis rs2153535 0.580 rs1414348 chr6:8471940 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs904251 0.523 rs2797798 chr6:37481437 C/T cg08126542 chr6:37504118 NA -0.44 -6.51 -0.5 1.71e-9 Cognitive performance; TGCT cis rs1451375 0.698 rs11489736 chr7:50645372 G/A cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs559928 0.576 rs750830 chr11:64163446 G/A cg12453748 chr11:64085041 PRDX5;TRMT112 0.57 4.95 0.41 2.36e-6 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs459571 1.000 rs456207 chr9:136911140 G/A cg14405625 chr9:136855902 VAV2 -0.3 -4.54 -0.38 1.3e-5 Platelet distribution width; TGCT cis rs9902453 0.933 rs7224199 chr17:28523726 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.35 0.43 4.09e-7 Coffee consumption (cups per day); TGCT cis rs9914988 0.887 rs2070265 chr17:27075423 A/G cg20469991 chr17:27169893 C17orf63 0.72 5.04 0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs3820068 0.656 rs72645829 chr1:15889748 A/G cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs7843479 0.601 rs4872204 chr8:21841396 T/C cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.08e-12 Mean corpuscular volume; TGCT cis rs11779988 0.545 rs438873 chr8:17786516 G/A cg01800426 chr8:17659068 MTUS1 -0.7 -5.46 -0.44 2.5e-7 Breast cancer; TGCT cis rs7312933 0.584 rs6582391 chr12:42634686 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.16 0.42 9.61e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2980439 0.556 rs2921059 chr8:8317887 G/T cg06636001 chr8:8085503 FLJ10661 0.77 7.11 0.54 8.23e-11 Neuroticism; TGCT cis rs4366490 0.687 rs1939752 chr11:62910214 G/A cg21002970 chr11:62369079 MTA2 0.71 5.03 0.41 1.66e-6 Conotruncal heart defects; TGCT cis rs2230307 0.536 rs580678 chr1:100483009 C/A cg24955406 chr1:100503596 HIAT1 0.74 4.83 0.4 4e-6 Carotid intima media thickness; TGCT cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs2404602 0.532 rs206205 chr15:76736091 T/G cg22467129 chr15:76604101 ETFA -0.42 -4.72 -0.39 6.24e-6 Blood metabolite levels; TGCT cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg02018176 chr4:1364513 KIAA1530 0.26 4.44 0.37 1.93e-5 Longevity; TGCT cis rs3806933 0.522 rs11241100 chr5:110460958 C/T cg04022379 chr5:110408740 TSLP 0.59 6.11 0.48 1.18e-8 Eosinophilic esophagitis; TGCT cis rs11190604 1.000 rs10883497 chr10:102228519 A/G cg23241863 chr10:102295624 HIF1AN 0.61 4.76 0.39 5.24e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1218582 0.682 rs12144978 chr1:154850445 G/A cg06221963 chr1:154839813 KCNN3 -0.77 -12.94 -0.76 9.36e-25 Prostate cancer; TGCT cis rs2153535 0.580 rs2143357 chr6:8497196 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs34526934 0.608 rs34720456 chr2:177027292 G/A cg00278547 chr2:177037212 HOXD3 -0.4 -4.98 -0.41 2.09e-6 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs7647973 0.731 rs9831648 chr3:49214303 G/T cg07690219 chr3:49449608 TCTA;RHOA -0.58 -4.54 -0.38 1.29e-5 Menarche (age at onset); TGCT cis rs7927592 0.546 rs554734 chr11:68192518 T/G cg16797656 chr11:68205561 LRP5 0.29 4.97 0.41 2.16e-6 Total body bone mineral density; TGCT cis rs4664308 0.967 rs62175559 chr2:160955833 G/A cg03641300 chr2:160917029 PLA2R1 -0.28 -6.84 -0.52 3.28e-10 Idiopathic membranous nephropathy; TGCT cis rs992157 0.643 rs10191283 chr2:219056755 G/A cg00012203 chr2:219082015 ARPC2 0.83 10.68 0.69 2.77e-19 Colorectal cancer; TGCT trans rs561341 0.831 rs11658469 chr17:30206426 T/C cg20587970 chr11:113659929 NA 0.8 9.45 0.65 2.65e-16 Hip circumference adjusted for BMI; TGCT cis rs6570726 0.791 rs11759979 chr6:145918881 C/T cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2730245 0.510 rs2788474 chr7:158649005 T/C cg24397884 chr7:158709396 WDR60 0.36 4.58 0.38 1.11e-5 Height; TGCT cis rs17376456 0.825 rs10476590 chr5:93244884 A/T cg25358565 chr5:93447407 FAM172A 1.01 7.9 0.58 1.29e-12 Diabetic retinopathy; TGCT cis rs7020830 0.825 rs13297152 chr9:37075623 C/T cg14294708 chr9:37120828 ZCCHC7 1.29 18.67 0.86 7.91e-38 Schizophrenia; TGCT cis rs2067615 0.524 rs4275715 chr12:107062246 C/T cg15890332 chr12:107067104 RFX4 0.28 5.56 0.45 1.59e-7 Heart rate; TGCT cis rs1552244 0.882 rs67631672 chr3:10004768 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.02 0.48 1.81e-8 Alzheimer's disease; TGCT cis rs7926906 1.000 rs12291122 chr11:90531578 A/C cg22332266 chr11:89956777 CHORDC1 -0.43 -4.5 -0.37 1.55e-5 Intelligence (multi-trait analysis); TGCT cis rs8141529 0.702 rs8137262 chr22:29292135 C/T cg02153584 chr22:29168773 CCDC117 0.64 4.91 0.4 2.87e-6 Lymphocyte counts; TGCT cis rs6089584 0.606 rs2273989 chr20:60579138 G/A cg13770153 chr20:60521292 NA -0.41 -5.12 -0.42 1.15e-6 Body mass index; TGCT cis rs11264213 0.591 rs408986 chr1:36551895 C/T cg27506609 chr1:36549197 TEKT2 0.47 5.52 0.44 1.9e-7 Schizophrenia; TGCT cis rs1218582 0.741 rs705094 chr1:154917314 G/A cg16680214 chr1:154839983 KCNN3 -0.37 -7.66 -0.57 4.71e-12 Prostate cancer; TGCT cis rs916888 0.773 rs199535 chr17:44822662 A/G cg01570182 chr17:44337453 NA 1.03 9.28 0.64 6.84e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17221829 0.614 rs10765236 chr11:89450030 G/A cg02982614 chr11:89391479 FOLH1B -0.29 -5.09 -0.42 1.3e-6 Anxiety in major depressive disorder; TGCT cis rs2370759 1.000 rs11594963 chr10:32625736 G/A cg01819863 chr10:32635814 EPC1 1.02 9.91 0.66 2.11e-17 Sexual dysfunction (female); TGCT cis rs1005277 0.579 rs2800485 chr10:38542588 G/A cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs910316 0.763 rs175047 chr14:75479039 C/G cg11812906 chr14:75593930 NEK9 -0.59 -5.69 -0.45 8.86e-8 Height; TGCT cis rs12142240 0.698 rs68012736 chr1:46839510 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs12765878 0.603 rs2475213 chr10:105664459 A/T cg11005552 chr10:105648138 OBFC1 0.41 6.46 0.5 2.15e-9 Coronary artery disease; TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs9467711 0.606 rs9366655 chr6:26377385 C/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs28595532 0.920 rs115797971 chr4:119779620 A/G cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs6500602 0.701 rs8129 chr16:4562351 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 7.29 0.55 3.2e-11 Schizophrenia; TGCT cis rs6586111 1.000 rs4934371 chr10:82372795 A/G cg03086067 chr10:82368399 SH2D4B 0.24 4.48 0.37 1.68e-5 Capecitabine sensitivity; TGCT cis rs6690583 0.623 rs12042910 chr1:85452580 G/A cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs17473412 0.926 rs115796963 chr5:122654779 A/G cg15125798 chr5:122621645 NA -0.66 -5.97 -0.47 2.29e-8 Total body bone mineral density; TGCT cis rs3796352 1.000 rs116616340 chr3:53132371 C/G cg07884673 chr3:53033167 SFMBT1 0.54 5.76 0.46 6.2e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs734999 0.967 rs6672381 chr1:2502834 A/G cg18854424 chr1:2615690 NA 0.47 5.92 0.47 3.01e-8 Ulcerative colitis; TGCT cis rs860554 0.510 rs2071960 chr1:201291066 C/T cg01022117 chr1:201258280 PKP1 -0.27 -4.91 -0.4 2.77e-6 Panic disorder; TGCT cis rs514406 0.621 rs881198 chr1:53196440 C/T cg16325326 chr1:53192061 ZYG11B -0.89 -12.84 -0.76 1.58e-24 Monocyte count; TGCT cis rs736408 0.924 rs2535629 chr3:52833219 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.24 0.49 6.45e-9 Bipolar disorder; TGCT cis rs62244186 0.659 rs9855433 chr3:44468065 C/A cg02073558 chr3:44770973 ZNF501 0.58 5.6 0.45 1.28e-7 Depressive symptoms; TGCT cis rs17331151 0.505 rs7614424 chr3:52566354 C/T cg07884673 chr3:53033167 SFMBT1 0.74 4.99 0.41 1.98e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2721195 0.577 rs4532636 chr8:145904423 A/C cg15320075 chr8:145703422 NA -0.63 -5.63 -0.45 1.14e-7 Age at first birth; TGCT cis rs9807989 0.507 rs6710528 chr2:103016142 A/G cg03938978 chr2:103052716 IL18RAP -0.28 -5.59 -0.45 1.39e-7 Asthma; TGCT cis rs7584330 0.910 rs6757376 chr2:238400036 G/C cg16989719 chr2:238392110 NA -0.29 -4.89 -0.4 3.01e-6 Prostate cancer; TGCT cis rs7267979 0.844 rs6083845 chr20:25388090 G/C cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8037137 0.915 rs2290202 chr15:91512267 G/T cg22570213 chr15:91497863 RCCD1 0.49 4.72 0.39 6.18e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs4240897 0.935 rs3766744 chr1:12043717 G/A cg05523254 chr1:12040215 MFN2 0.47 4.51 0.38 1.5e-5 Tuberculosis; TGCT cis rs2307449 0.704 rs758131 chr15:89884301 T/A cg01877814 chr15:89879097 POLG 0.29 4.46 0.37 1.83e-5 Menopause (age at onset); TGCT cis rs12368653 1.000 rs12371356 chr12:58135420 T/C cg12615879 chr12:58013172 SLC26A10 0.46 5.72 0.46 7.65e-8 Multiple sclerosis; TGCT cis rs4631830 0.900 rs4630241 chr10:51532751 G/A cg10326726 chr10:51549505 MSMB -0.27 -5.38 -0.43 3.6e-7 Prostate-specific antigen levels; TGCT cis rs999943 0.846 rs999942 chr6:33624902 G/C cg14003231 chr6:33640908 ITPR3 0.4 4.86 0.4 3.48e-6 Obesity (extreme); TGCT cis rs595982 0.661 rs657008 chr19:49373632 A/G cg15549821 chr19:49342101 PLEKHA4 -0.37 -5.05 -0.41 1.56e-6 Red cell distribution width; TGCT cis rs11190604 0.725 rs9420796 chr10:102323092 G/C cg16342193 chr10:102329863 NA -0.4 -5.08 -0.42 1.32e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2836950 0.509 rs4816618 chr21:40599529 G/A cg11644478 chr21:40555479 PSMG1 -0.54 -5.1 -0.42 1.25e-6 Menarche (age at onset); TGCT cis rs7666738 0.830 rs6829567 chr4:99047340 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 1.000 rs12602346 chr17:56901713 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs7726839 1.000 rs7726839 chr5:618586 A/G cg09021430 chr5:549028 NA -0.38 -5.52 -0.44 1.93e-7 Obesity-related traits; TGCT cis rs7044106 0.537 rs10818474 chr9:123489964 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.48 5.22 0.42 7.39e-7 Hip circumference adjusted for BMI; TGCT cis rs7267979 0.844 rs6107017 chr20:25232300 A/G cg16686733 chr20:25566563 NINL 0.52 4.9 0.4 2.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg06634786 chr22:41940651 POLR3H 0.89 8.81 0.62 9.46e-15 Vitiligo; TGCT cis rs559928 0.556 rs11607903 chr11:63932140 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.56 0.38 1.22e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs4665630 0.708 rs115460150 chr2:23896434 C/A cg08063864 chr2:24346004 PFN4;LOC375190 1.0 4.97 0.41 2.17e-6 Hypertension; TGCT cis rs12681287 0.547 rs13267858 chr8:87510871 G/A cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs7826238 0.566 rs2945886 chr8:8148270 C/G cg06636001 chr8:8085503 FLJ10661 0.76 6.8 0.52 3.97e-10 Systolic blood pressure; TGCT cis rs6582630 0.555 rs11182217 chr12:38480030 G/A cg13010199 chr12:38710504 ALG10B 0.61 4.81 0.4 4.34e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs79387448 0.745 rs7582378 chr2:103162263 C/A cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT trans rs1005277 0.541 rs1740741 chr10:38515334 C/T cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs568617 0.768 rs12225345 chr11:65647105 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.67 5.7 0.46 8.36e-8 Crohn's disease; TGCT cis rs7666738 0.830 rs7673385 chr4:99024922 T/G cg05340658 chr4:99064831 C4orf37 0.51 5.82 0.46 4.75e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs5750830 0.621 rs5750810 chr22:39792943 A/G cg11247378 chr22:39784982 NA -0.75 -9.73 -0.66 5.69e-17 Intelligence (multi-trait analysis); TGCT cis rs7659604 0.540 rs4075065 chr4:122683906 A/G cg19748678 chr4:122722346 EXOSC9 -0.48 -4.86 -0.4 3.54e-6 Type 2 diabetes; TGCT cis rs916888 0.773 rs199533 chr17:44828931 G/A cg16520312 chr17:43971471 MAPT;LOC100128977 -0.64 -5.57 -0.45 1.53e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9916302 0.851 rs9909064 chr17:37500434 G/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg03264133 chr6:25882463 NA 0.86 8.88 0.62 6.24e-15 Blood metabolite levels; TGCT cis rs910316 0.935 rs175422 chr14:75627319 T/A cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.84e-6 Height; TGCT cis rs66569888 0.507 rs67196165 chr2:106886496 C/G cg15412446 chr2:106886593 NA -0.53 -6.76 -0.52 4.9e-10 Facial morphology (factor 23); TGCT cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs4919694 0.808 rs112574306 chr10:104971159 C/T cg04362960 chr10:104952993 NT5C2 1.09 6.67 0.51 7.46e-10 Arsenic metabolism; TGCT cis rs9733 0.650 rs11204680 chr1:150587140 T/G cg13175981 chr1:150552382 MCL1 0.54 6.13 0.48 1.09e-8 Tonsillectomy; TGCT cis rs9303401 0.703 rs9911583 chr17:57210721 A/G cg12560992 chr17:57184187 TRIM37 -0.47 -4.55 -0.38 1.28e-5 Cognitive test performance; TGCT cis rs6586163 0.872 rs7910825 chr10:90743341 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.38 -4.7 -0.39 6.86e-6 Chronic lymphocytic leukemia; TGCT trans rs941408 1.000 rs1640274 chr19:2807375 G/A cg22153745 chr1:153894579 GATAD2B -0.7 -6.98 -0.53 1.57e-10 Total cholesterol levels; TGCT cis rs2153535 0.580 rs1119690 chr6:8460660 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs548987 0.507 rs1408268 chr6:25826986 T/A cg03264133 chr6:25882463 NA -0.54 -4.44 -0.37 1.99e-5 Homocysteine levels; TGCT cis rs826838 0.586 rs10880753 chr12:38628147 C/A cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs117785887 0.536 rs12205195 chr6:146364300 G/A cg06708562 chr6:146285465 SHPRH -0.8 -4.81 -0.4 4.23e-6 Interleukin-17 levels; TGCT cis rs67311347 1.000 rs7648952 chr3:40457038 C/T cg17264618 chr3:40429014 ENTPD3 -0.32 -4.76 -0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs1467026 0.691 rs9985266 chr3:12803162 C/T cg05775895 chr3:12838266 CAND2 -0.55 -5.25 -0.43 6.5e-7 P wave duration; TGCT cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs1023500 0.573 rs1807494 chr22:42474138 C/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Schizophrenia; TGCT cis rs921968 0.541 rs620596 chr2:219462419 G/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs769267 0.895 rs1858999 chr19:19497669 C/G cg08509172 chr19:19383838 TM6SF2 0.33 4.46 0.37 1.83e-5 Tonsillectomy; TGCT cis rs10838634 1.000 rs7112060 chr11:46891901 C/T cg18332754 chr11:46939436 LRP4 0.89 4.77 0.39 5.13e-6 Schizophrenia; TGCT cis rs2153535 0.580 rs7341383 chr6:8470634 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2735413 0.564 rs74316728 chr16:78099653 C/T cg09132178 chr16:78079569 NA 0.36 4.5 0.37 1.55e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg16145915 chr7:1198662 ZFAND2A -0.59 -8.2 -0.59 2.64e-13 Longevity;Endometriosis; TGCT cis rs12530134 1.000 rs12530134 chr6:170919470 G/A cg02645993 chr6:170674463 FAM120B 0.36 4.53 0.38 1.35e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg19626725 chr5:178986131 RUFY1 0.49 6.09 0.48 1.31e-8 Lung cancer; TGCT cis rs981844 1.000 rs62325105 chr4:154673846 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs7267979 1.000 rs2482941 chr20:25361216 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1577917 0.771 rs2842602 chr6:86331887 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.57 -0.45 1.5e-7 Response to antipsychotic treatment; TGCT cis rs77741769 0.571 rs1542859 chr12:121336766 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.56e-5 Mean corpuscular volume; TGCT cis rs9368481 0.594 rs2636425 chr6:26799460 A/G cg02458000 chr6:26745757 NA 0.59 5.14 0.42 1.03e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4821897 0.514 rs739141 chr22:39824450 A/G cg24399712 chr22:39784796 NA 0.96 11.54 0.72 2.26e-21 IgG glycosylation; TGCT cis rs968567 0.539 rs174555 chr11:61579760 T/C cg19610905 chr11:61596333 FADS2 -1.05 -11.51 -0.72 2.6e-21 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs11030122 0.702 rs10767702 chr11:3934132 T/C cg18678763 chr11:4115507 RRM1 -0.52 -6.41 -0.5 2.8e-9 Mean platelet volume;Platelet distribution width; TGCT cis rs36051895 0.695 rs4527935 chr9:5016455 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.35 -0.64 4.65e-16 Pediatric autoimmune diseases; TGCT cis rs4293393 1.000 rs13333226 chr16:20365654 A/G cg26923810 chr16:20935690 LYRM1 0.2 4.44 0.37 2e-5 Chronic kidney disease and serum creatinine levels; TGCT cis rs9911578 0.839 rs1871751 chr17:57190368 A/G cg05425664 chr17:57184151 TRIM37 -0.65 -6.5 -0.5 1.77e-9 Intelligence (multi-trait analysis); TGCT cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg13770153 chr20:60521292 NA 0.56 6.96 0.53 1.71e-10 Body mass index; TGCT cis rs6060960 0.502 rs6057968 chr20:30082779 A/T cg21427119 chr20:30132790 HM13 -0.39 -5.56 -0.45 1.58e-7 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs204693 0.547 rs205894 chr20:543616 T/C cg15180867 chr20:591076 TCF15 -0.65 -4.48 -0.37 1.69e-5 Pursuit maintenance gain; TGCT cis rs7568458 0.777 rs12473819 chr2:85773061 A/G cg17127132 chr2:85788382 GGCX 0.7 6.64 0.51 8.96e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs713587 0.934 rs6728219 chr2:25159172 T/C cg01884057 chr2:25150051 NA 0.4 8.24 0.59 2.03e-13 Body mass index in non-asthmatics; TGCT cis rs2806561 0.765 rs1757046 chr1:23511821 T/C cg12483005 chr1:23474871 LUZP1 0.38 4.72 0.39 6.25e-6 Height; TGCT cis rs1005224 0.926 rs7143743 chr14:76127805 G/C cg25116370 chr14:76127843 TTLL5;C14orf1 -0.55 -4.94 -0.41 2.42e-6 Large artery stroke; TGCT cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg05985448 chr10:134359359 INPP5A 0.23 4.99 0.41 2.01e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1568889 1.000 rs12794100 chr11:28332785 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.8 0.62 9.95e-15 Bipolar disorder; TGCT cis rs7666738 0.830 rs13102652 chr4:99006737 T/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs1532993 0.518 rs6822369 chr4:98643888 A/T cg05340658 chr4:99064831 C4orf37 -0.4 -4.87 -0.4 3.32e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs8177253 0.514 rs6790668 chr3:133442481 T/A cg24879335 chr3:133465180 TF 0.37 5.0 0.41 1.93e-6 Iron status biomarkers; TGCT cis rs7100689 0.646 rs10788586 chr10:82117435 A/G cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs1362404 0.648 rs4784889 chr16:51969854 C/A cg03955530 chr16:52681474 NA 0.28 4.5 0.37 1.56e-5 Gut microbiota (bacterial taxa); TGCT cis rs7772486 0.875 rs2073287 chr6:146350264 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6964587 0.867 rs12704637 chr7:91874686 C/T cg17063962 chr7:91808500 NA 0.86 8.63 0.61 2.53e-14 Breast cancer; TGCT cis rs11212617 1.000 rs228591 chr11:108097333 A/G cg16693212 chr11:108093249 ATM;NPAT 0.48 4.54 0.38 1.33e-5 Response to metformin in type 2 diabetes (glycemic); TGCT cis rs922182 0.617 rs2899697 chr15:64240436 T/C cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.35e-10 Blood protein levels; TGCT cis rs35146811 0.735 rs2272344 chr7:99786819 C/T cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs875971 0.862 rs4718383 chr7:66108409 T/C cg11764359 chr7:65958608 NA -0.55 -4.98 -0.41 2.1e-6 Aortic root size; TGCT cis rs28493229 0.522 rs2287692 chr19:41289756 G/A cg23743927 chr19:41304969 EGLN2 -0.74 -4.67 -0.39 7.7e-6 Kawasaki disease; TGCT cis rs13064447 0.967 rs9873195 chr3:12767936 A/G cg20675869 chr3:12750130 NA 0.19 4.81 0.4 4.3e-6 Major depression and alcohol dependence; TGCT cis rs6500602 0.702 rs2270366 chr16:4558615 A/G cg08645402 chr16:4508243 NA -0.18 -4.91 -0.4 2.83e-6 Schizophrenia; TGCT cis rs6964587 1.000 rs3753107 chr7:91629151 C/T cg17063962 chr7:91808500 NA -0.89 -9.88 -0.66 2.44e-17 Breast cancer; TGCT cis rs11696501 0.739 rs6104257 chr20:44262100 G/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.69 -0.39 7.08e-6 Brain structure; TGCT cis rs9972944 0.756 rs8072765 chr17:63763508 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.29 -0.43 5.45e-7 Total body bone mineral density; TGCT cis rs589448 0.902 rs315113 chr12:69786543 G/T cg11871910 chr12:69753446 YEATS4 -0.88 -10.58 -0.69 4.98e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs9383153 0.793 rs6937740 chr6:16348080 C/T cg14009473 chr6:15502099 JARID2 0.62 4.94 0.41 2.5e-6 Gambling; TGCT cis rs9549367 0.789 rs9549365 chr13:113907391 C/T cg00898013 chr13:113819073 PROZ 0.42 5.41 0.44 3.19e-7 Platelet distribution width; TGCT cis rs2180341 0.924 rs6930849 chr6:127630963 A/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs8014204 0.806 rs11159104 chr14:75293374 A/G cg06637938 chr14:75390232 RPS6KL1 0.7 6.74 0.52 5.37e-10 Caffeine consumption; TGCT cis rs9926296 0.585 rs8058009 chr16:89856439 G/A cg04287289 chr16:89883240 FANCA 0.72 6.72 0.52 5.84e-10 Vitiligo; TGCT cis rs6912958 0.559 rs242281 chr6:88048916 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.72 7.53 0.56 9.05e-12 Monocyte percentage of white cells; TGCT cis rs4629710 0.592 rs4310080 chr6:131538377 T/G cg12606694 chr6:131520996 AKAP7 0.39 4.57 0.38 1.17e-5 Multiple myeloma (IgH translocation); TGCT cis rs9486715 1.000 rs11153082 chr6:97059666 A/G cg06623918 chr6:96969491 KIAA0776 -1.12 -15.49 -0.81 8.72e-31 Headache; TGCT cis rs11025559 0.773 rs10833334 chr11:20498640 T/C cg19653624 chr11:20408972 PRMT3 -0.64 -4.85 -0.4 3.59e-6 Pursuit maintenance gain; TGCT cis rs7635838 0.892 rs6792718 chr3:11434380 A/G cg00170343 chr3:11313890 ATG7 0.65 6.23 0.49 6.56e-9 HDL cholesterol; TGCT cis rs72781680 0.821 rs72781644 chr2:24209348 T/C cg08917208 chr2:24149416 ATAD2B 0.72 4.5 0.37 1.56e-5 Lymphocyte counts; TGCT cis rs2380220 0.541 rs72928273 chr6:96079360 C/T cg04719120 chr6:96025338 MANEA -0.7 -5.13 -0.42 1.08e-6 Behavioural disinhibition (generation interaction); TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs228437 0.586 rs9494012 chr6:134964646 A/G cg09872934 chr6:134495829 SGK1 -0.58 -4.74 -0.39 5.66e-6 Melanoma; TGCT cis rs7017914 0.905 rs3098868 chr8:71929692 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs2153535 0.580 rs2184586 chr6:8474182 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.03 0.41 1.66e-6 Height; TGCT cis rs3008870 0.755 rs1024230 chr1:67512920 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.79 7.31 0.55 2.83e-11 Lymphocyte percentage of white cells; TGCT cis rs11190604 0.767 rs79106148 chr10:102184732 G/A cg16005271 chr10:102321736 NA 0.46 4.67 0.39 7.62e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1669338 0.507 rs4685609 chr3:3202279 T/C cg16797762 chr3:3221439 CRBN -0.89 -5.67 -0.45 9.6e-8 White matter integrity; TGCT trans rs17685 0.753 rs2868203 chr7:75680026 G/A cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1552244 0.882 rs55808392 chr3:10054681 C/T cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs7267979 0.903 rs6115101 chr20:25229564 C/A cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2657888 0.931 rs7301093 chr12:56933244 G/T cg23002907 chr12:56915593 RBMS2 0.44 6.14 0.48 1.03e-8 Adiponectin levels; TGCT cis rs829883 0.664 rs865509 chr12:98854444 T/A cg25150519 chr12:98850993 NA 0.64 7.54 0.56 8.56e-12 Colorectal adenoma (advanced); TGCT cis rs28374715 0.662 rs8038983 chr15:41473316 G/A cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.5 -0.72 2.84e-21 Ulcerative colitis; TGCT cis rs6840360 0.642 rs1443090 chr4:152451819 T/C cg17479576 chr4:152424074 FAM160A1 -0.62 -6.7 -0.52 6.64e-10 Intelligence (multi-trait analysis); TGCT cis rs6495367 1.000 rs28412916 chr15:79378167 A/C cg17916960 chr15:79447300 NA 0.36 5.21 0.42 7.56e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1215050 0.791 rs13114823 chr4:98671119 G/A cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs910316 0.935 rs175448 chr14:75591071 G/A cg08847533 chr14:75593920 NEK9 -0.94 -10.33 -0.68 2.03e-18 Height; TGCT cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg08048268 chr3:133502702 NA -0.54 -7.08 -0.54 9.62e-11 Iron status biomarkers; TGCT cis rs6684514 0.961 rs10908497 chr1:156274740 G/A cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6714710 0.603 rs11690687 chr2:98461821 C/T cg26665480 chr2:98280029 ACTR1B 0.64 6.1 0.48 1.26e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs28785552 0.589 rs11669056 chr19:53244443 G/A cg04754360 chr19:53238445 ZNF611 -0.62 -4.89 -0.4 3.09e-6 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs10540 0.558 rs12806062 chr11:501429 G/A cg03934478 chr11:495069 RNH1 0.32 4.96 0.41 2.28e-6 Body mass index; TGCT cis rs6964587 0.782 rs13221571 chr7:91500236 C/T cg17063962 chr7:91808500 NA -0.86 -9.21 -0.64 1.02e-15 Breast cancer; TGCT cis rs910316 0.737 rs175499 chr14:75535927 G/A cg08847533 chr14:75593920 NEK9 -0.84 -8.46 -0.6 6.38e-14 Height; TGCT cis rs611744 0.647 rs674391 chr8:109242803 A/T cg21045802 chr8:109455806 TTC35 0.69 6.96 0.53 1.73e-10 Dupuytren's disease; TGCT cis rs4654899 0.865 rs72988025 chr1:21351441 A/G cg01072550 chr1:21505969 NA -0.46 -6.95 -0.53 1.88e-10 Superior frontal gyrus grey matter volume; TGCT cis rs752010 0.631 rs1073197 chr1:42059822 C/T cg06885757 chr1:42089581 HIVEP3 -0.29 -5.21 -0.42 7.78e-7 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg19774624 chr17:42201019 HDAC5 -0.89 -10.87 -0.7 9.7e-20 Total body bone mineral density; TGCT cis rs9467711 0.659 rs35277236 chr6:26562269 G/T cg16898833 chr6:26189333 HIST1H4D 1.25 5.86 0.47 3.88e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs6882046 0.513 rs447801 chr5:88002653 T/C cg22951263 chr5:87985283 NA -0.61 -6.53 -0.51 1.49e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT trans rs28735056 0.935 rs552957 chr18:77595748 G/A cg05926928 chr17:57297772 GDPD1 -0.68 -6.88 -0.53 2.61e-10 Schizophrenia; TGCT cis rs2033711 0.840 rs3764533 chr19:58929194 A/G cg13877915 chr19:58951672 ZNF132 0.88 10.81 0.7 1.36e-19 Uric acid clearance; TGCT cis rs1371867 0.846 rs1616833 chr8:101271821 C/T cg00191853 chr8:101177733 SPAG1 0.23 4.8 0.4 4.44e-6 Atrioventricular conduction; TGCT cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg12310025 chr6:25882481 NA -0.66 -5.74 -0.46 6.73e-8 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg26531700 chr6:26746687 NA 0.5 4.65 0.39 8.29e-6 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.520 rs13012481 chr2:99754290 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 17.85 0.85 4.6e-36 Chronic sinus infection; TGCT trans rs916888 0.610 rs199442 chr17:44820122 G/A cg01341218 chr17:43662625 NA 0.85 7.42 0.55 1.63e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs5769765 1.000 rs1033665 chr22:50252127 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.87 -0.73 3.47e-22 Schizophrenia; TGCT cis rs6728642 0.908 rs7588921 chr2:98021001 C/T cg26665480 chr2:98280029 ACTR1B -0.96 -5.21 -0.42 7.79e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs2880765 0.835 rs4843062 chr15:86040137 A/G cg13263323 chr15:86062960 AKAP13 -0.22 -4.83 -0.4 3.97e-6 Coronary artery disease; TGCT cis rs9318086 0.712 rs9318100 chr13:24442482 A/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.77 -8.22 -0.59 2.29e-13 Myopia (pathological); TGCT cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9583531 0.689 rs4773244 chr13:111383937 A/T cg24331049 chr13:111365604 ING1 -0.88 -8.92 -0.63 5.11e-15 Coronary artery disease; TGCT cis rs1005277 0.579 rs2472183 chr10:38392495 T/G cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs4727027 0.933 rs12532104 chr7:148864233 A/C cg23583168 chr7:148888333 NA -0.76 -10.09 -0.67 7.46e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2153535 0.623 rs2152346 chr6:8454652 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2243480 0.803 rs160649 chr7:65543199 C/T cg18252515 chr7:66147081 NA -1.13 -7.39 -0.55 1.94e-11 Diabetic kidney disease; TGCT cis rs7772486 0.790 rs7753696 chr6:146279098 G/T cg23711669 chr6:146136114 FBXO30 -0.89 -10.17 -0.67 4.95e-18 Lobe attachment (rater-scored or self-reported); TGCT trans rs10506458 0.915 rs12426308 chr12:63405778 C/T cg22491629 chr6:157744540 C6orf35 -1.0 -8.59 -0.61 3.09e-14 Hemostatic factors and hematological phenotypes; TGCT trans rs2688482 0.512 rs2177336 chr3:195516878 T/C cg17952111 chr19:54960355 LENG8 0.84 6.88 0.53 2.64e-10 Lung disease severity in cystic fibrosis; TGCT cis rs376008 0.526 rs2305742 chr19:18191441 A/C cg15085805 chr19:18433592 LSM4 0.52 4.74 0.39 5.79e-6 Blood protein levels; TGCT cis rs929354 0.772 rs1002389 chr7:156968323 C/G cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs807669 0.903 rs807667 chr22:19161327 A/G cg02655711 chr22:19163373 SLC25A1 -0.42 -10.06 -0.67 8.99e-18 Metabolite levels; TGCT cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.98 7.97 0.58 8.82e-13 Platelet count; TGCT cis rs10510102 0.872 rs7916380 chr10:123703288 C/A cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg11905131 chr22:24372483 LOC391322 -0.95 -11.08 -0.71 2.91e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs425277 0.606 rs2459984 chr1:2086312 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.54 -0.38 1.34e-5 Height; TGCT cis rs2204008 0.744 rs2222344 chr12:38406832 T/G cg26384229 chr12:38710491 ALG10B 0.83 7.58 0.56 6.92e-12 Bladder cancer; TGCT cis rs10992471 0.580 rs1535756 chr9:95202032 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.67 -0.45 9.42e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3617 0.598 rs56214994 chr3:52878600 G/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2180341 1.000 rs2326567 chr6:127606160 G/A cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs7192750 0.563 rs11649672 chr16:71952614 G/C cg06353428 chr16:71660113 MARVELD3 0.82 7.26 0.55 3.65e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs1670533 1.000 rs2045065 chr4:1052488 A/G cg27284194 chr4:1044797 NA 0.66 5.49 0.44 2.22e-7 Recombination rate (females); TGCT trans rs1005277 0.579 rs1780146 chr10:38517874 C/A cg17830980 chr10:43048298 ZNF37B -0.82 -10.26 -0.68 2.99e-18 Extrinsic epigenetic age acceleration; TGCT cis rs79976124 0.842 rs7760550 chr6:66628788 T/C cg07460842 chr6:66804631 NA 0.59 5.34 0.43 4.3e-7 Type 2 diabetes; TGCT cis rs12188164 0.930 rs72717436 chr5:448291 C/A cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg00684032 chr4:1343700 KIAA1530 -0.22 -4.73 -0.39 6.06e-6 Obesity-related traits; TGCT cis rs826838 0.967 rs11168985 chr12:39045983 A/C cg26384229 chr12:38710491 ALG10B -0.84 -6.91 -0.53 2.3e-10 Heart rate; TGCT cis rs6543140 0.964 rs11903551 chr2:103084181 C/G cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs28374715 0.681 rs28712264 chr15:41588797 T/C cg18705301 chr15:41695430 NDUFAF1 -0.86 -12.43 -0.74 1.54e-23 Ulcerative colitis; TGCT cis rs597539 0.616 rs631001 chr11:68642974 C/T cg06112835 chr11:68658793 MRPL21 0.47 8.18 0.59 2.86e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg10547057 chr6:26987810 LOC100270746;C6orf41 -0.47 -4.88 -0.4 3.15e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4688759 0.609 rs113176147 chr3:49534439 G/T cg08550065 chr3:50336684 HYAL3;NAT6 1.22 4.93 0.4 2.58e-6 Blood protein levels; TGCT cis rs10193935 0.901 rs62142639 chr2:42600019 C/G cg27598129 chr2:42591480 NA -0.4 -5.44 -0.44 2.71e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4704846 0.904 rs11741184 chr5:156515406 C/G cg12943317 chr5:156479607 HAVCR1 0.32 4.73 0.39 6.1e-6 Blood protein levels; TGCT cis rs826838 0.616 rs2387921 chr12:38624767 T/C cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs1005224 0.864 rs11625011 chr14:76144828 G/A cg04684003 chr14:76127793 TTLL5;C14orf1 -0.62 -5.75 -0.46 6.6e-8 Large artery stroke; TGCT cis rs2072499 0.554 rs1052067 chr1:156206121 C/T cg25208724 chr1:156163844 SLC25A44 0.65 5.51 0.44 1.96e-7 Testicular germ cell tumor; TGCT cis rs5750830 0.645 rs4821890 chr22:39777523 G/A cg02038168 chr22:39784481 NA -0.68 -6.13 -0.48 1.05e-8 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs75934770 chr2:43659694 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.45 -5.35 -0.43 4.03e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1215050 0.791 rs1025201 chr4:98902938 A/G cg17366294 chr4:99064904 C4orf37 -0.53 -5.69 -0.45 8.67e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7917772 0.582 rs12782153 chr10:104368294 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.46 -0.44 2.51e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs554111 0.613 rs10753510 chr1:21412248 G/A cg01072550 chr1:21505969 NA 0.36 5.46 0.44 2.51e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs838147 0.507 rs1704773 chr19:49209566 A/G cg05248581 chr19:49925731 PTH2 0.41 4.51 0.38 1.5e-5 Dietary macronutrient intake; TGCT cis rs80282103 0.867 rs7098169 chr10:1078601 G/A cg08668510 chr10:1095578 IDI1 1.12 4.67 0.39 7.72e-6 Glomerular filtration rate (creatinine); TGCT cis rs1218582 0.741 rs7544528 chr1:154844585 C/T cg09359103 chr1:154839909 KCNN3 -0.74 -15.86 -0.82 1.26e-31 Prostate cancer; TGCT cis rs4665809 1.000 rs2384321 chr2:26290054 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs7681440 0.869 rs7680557 chr4:90763360 C/A cg26578617 chr4:90757533 SNCA -0.49 -5.1 -0.42 1.26e-6 Dementia with Lewy bodies; TGCT cis rs3885907 0.542 rs9315047 chr13:31321289 T/A cg22282089 chr13:30686841 NA -0.22 -4.6 -0.38 1.03e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT cis rs494003 1.000 rs494003 chr11:65542298 G/A cg04293602 chr11:65553660 OVOL1 0.36 4.65 0.39 8.51e-6 Systemic lupus erythematosus; TGCT cis rs7666738 0.830 rs7678250 chr4:98922109 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.897 rs7432989 chr3:49105136 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 3e-7 Parkinson's disease; TGCT cis rs9926296 0.624 rs1110331 chr16:89774396 A/G cg26513180 chr16:89883248 FANCA -0.56 -4.93 -0.4 2.62e-6 Vitiligo; TGCT cis rs7674212 0.541 rs2720460 chr4:104054686 C/T cg16532752 chr4:104119610 CENPE 0.56 4.9 0.4 2.93e-6 Type 2 diabetes; TGCT cis rs11031096 0.542 rs6578424 chr11:3973140 G/A cg08557956 chr11:4115526 RRM1 -0.49 -4.44 -0.37 1.97e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1215050 0.791 rs155019 chr4:98759126 G/A cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2688608 0.933 rs2633307 chr10:75653881 G/A cg19442545 chr10:75533431 FUT11 -0.29 -4.63 -0.38 8.99e-6 Inflammatory bowel disease; TGCT cis rs6879260 1.000 rs10903252 chr5:179733934 T/C cg02891314 chr5:179741120 GFPT2 -0.41 -7.16 -0.54 6.21e-11 Height; TGCT cis rs11025559 0.796 rs10833317 chr11:20412277 A/T cg19653624 chr11:20408972 PRMT3 -0.62 -4.84 -0.4 3.73e-6 Pursuit maintenance gain; TGCT cis rs4808199 0.948 rs11085261 chr19:19462606 G/A cg03709012 chr19:19516395 GATAD2A 0.81 6.55 0.51 1.4e-9 Nonalcoholic fatty liver disease; TGCT cis rs17331151 0.512 rs9637477 chr3:52891426 G/C cg15956490 chr3:53032818 SFMBT1 -0.47 -5.9 -0.47 3.27e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7432375 0.800 rs1280622 chr3:136508008 C/A cg12473912 chr3:136751656 NA -0.34 -4.77 -0.39 5.06e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs12989701 0.877 rs35860453 chr2:127866047 C/T cg08168897 chr2:127865431 BIN1 0.53 5.77 0.46 6.05e-8 Alzheimer's disease (late onset); TGCT cis rs13242816 0.892 rs34205980 chr7:116078406 T/A cg02799643 chr7:116139180 CAV2 -0.43 -5.08 -0.42 1.33e-6 P wave duration; TGCT cis rs208520 0.837 rs208498 chr6:66931560 G/A cg07460842 chr6:66804631 NA -0.9 -9.15 -0.63 1.45e-15 Exhaled nitric oxide output; TGCT cis rs12142240 0.698 rs68191463 chr1:46808695 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs3096299 0.900 rs2911258 chr16:89480760 A/G cg06640241 chr16:89574553 SPG7 0.65 6.33 0.49 4.05e-9 Multiple myeloma (IgH translocation); TGCT cis rs539096 0.872 rs2478978 chr1:44031657 C/T cg12908607 chr1:44402522 ARTN 0.49 5.19 0.42 8.41e-7 Intelligence (multi-trait analysis); TGCT cis rs3809566 0.613 rs16946330 chr15:63324501 C/G cg00520135 chr15:63333846 TPM1 0.4 4.81 0.4 4.25e-6 Platelet count; TGCT cis rs9527 1.000 rs9527 chr10:104623578 C/T cg04362960 chr10:104952993 NT5C2 0.64 5.24 0.43 6.75e-7 Arsenic metabolism; TGCT cis rs9325144 0.560 rs6582539 chr12:38630097 C/T cg26384229 chr12:38710491 ALG10B -0.67 -5.95 -0.47 2.55e-8 Morning vs. evening chronotype; TGCT cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg07636037 chr3:49044803 WDR6 0.86 8.45 0.6 6.53e-14 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs1348850 0.914 rs4341974 chr2:178324879 A/C cg22681709 chr2:178499509 PDE11A -0.37 -4.89 -0.4 3.01e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9611565 0.918 rs2281333 chr22:41749630 T/C cg02107564 chr22:41488750 EP300 -0.54 -4.44 -0.37 1.96e-5 Vitiligo; TGCT cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs7523050 0.643 rs34572569 chr1:109401856 A/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs3733585 0.683 rs13112015 chr4:9933796 C/T cg11266682 chr4:10021025 SLC2A9 -0.57 -7.3 -0.55 3.08e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs17711722 0.727 rs781151 chr7:65479878 T/C cg00343986 chr7:65444356 GUSB 0.24 5.41 0.44 3.13e-7 Calcium levels; TGCT cis rs4788570 0.510 rs9931074 chr16:71667680 C/T cg06353428 chr16:71660113 MARVELD3 1.54 12.33 0.74 2.73e-23 Intelligence (multi-trait analysis); TGCT cis rs3764400 0.567 rs4995899 chr17:46150730 G/A cg02340556 chr17:46797764 NA 0.41 4.47 0.37 1.72e-5 Body mass index; TGCT cis rs7191439 0.858 rs7205626 chr16:88780472 T/C cg27087555 chr16:88793112 FAM38A -0.43 -4.87 -0.4 3.4e-6 Plateletcrit; TGCT cis rs2046867 0.862 rs58538718 chr3:72800563 C/A cg25664220 chr3:72788482 NA -0.57 -7.05 -0.53 1.13e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7267979 1.000 rs2500404 chr20:25359758 A/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1801251 1.000 rs2012221 chr2:233566848 T/C cg25237894 chr2:233734115 C2orf82 0.32 5.58 0.45 1.45e-7 Coronary artery disease; TGCT cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg03303774 chr4:1407052 NA 0.33 4.96 0.41 2.31e-6 Obesity-related traits; TGCT cis rs2562456 0.876 rs11085468 chr19:21751889 C/T cg25650185 chr19:21324782 ZNF431 -0.64 -5.7 -0.46 8.24e-8 Pain; TGCT cis rs3733585 0.699 rs28613263 chr4:9964880 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.68 -0.51 7.36e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6892003 0.857 rs10071232 chr5:174180140 G/T cg06056415 chr5:174162510 NA 0.44 4.62 0.38 9.46e-6 Clopidogrel active metabolite levels; TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg27535305 chr1:53392650 SCP2 -0.25 -5.06 -0.41 1.47e-6 Monocyte count; TGCT cis rs13242816 0.881 rs55930206 chr7:116172850 C/T cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs3617 0.573 rs2336667 chr3:52916363 C/T cg11645453 chr3:52864694 ITIH4 -0.27 -5.17 -0.42 9.18e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2013441 1.000 rs8074047 chr17:20176703 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.66 -0.39 8.02e-6 Obesity-related traits; TGCT cis rs9393692 0.840 rs9358915 chr6:26277268 G/A cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.01e-7 Educational attainment; TGCT cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs597539 0.652 rs654071 chr11:68653432 A/C cg21862992 chr11:68658383 NA 0.47 6.54 0.51 1.42e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs826838 0.802 rs10785619 chr12:38742897 T/A cg26384229 chr12:38710491 ALG10B 0.89 8.19 0.59 2.66e-13 Heart rate; TGCT cis rs7917772 0.503 rs7915589 chr10:104299264 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2153535 0.601 rs9505473 chr6:8538777 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs1153858 1.000 rs7164602 chr15:45671325 A/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs524281 0.731 rs2452682 chr11:65812609 C/T cg00563793 chr11:65837595 PACS1 0.61 4.46 0.37 1.85e-5 Electroencephalogram traits; TGCT cis rs2242116 0.796 rs9852082 chr3:46972377 T/C cg27129171 chr3:47204927 SETD2 0.66 6.23 0.49 6.52e-9 Birth weight; TGCT cis rs7208859 0.562 rs216408 chr17:28907757 C/G cg14008862 chr17:28927542 LRRC37B2 -0.73 -4.7 -0.39 6.84e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg17971929 chr21:40555470 PSMG1 0.97 9.51 0.65 1.95e-16 Cognitive function; TGCT cis rs6586163 0.872 rs7082720 chr10:90742049 C/T cg03111039 chr10:90751583 FAS;ACTA2 -0.36 -4.47 -0.37 1.76e-5 Chronic lymphocytic leukemia; TGCT cis rs9549367 0.789 rs9577218 chr13:113894911 A/G cg18105134 chr13:113819100 PROZ -0.35 -5.94 -0.47 2.68e-8 Platelet distribution width; TGCT cis rs9314614 0.899 rs2977802 chr8:6694845 C/G cg27319216 chr8:6693540 XKR5 0.27 4.64 0.38 8.77e-6 IgA nephropathy;White blood cell count (basophil); TGCT trans rs208520 0.661 rs851466 chr6:66840476 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT trans rs12339966 0.580 rs2171664 chr9:11292003 T/C cg07173112 chr1:1114698 TTLL10 -0.34 -6.77 -0.52 4.66e-10 Systolic blood pressure; TGCT cis rs10193935 1.000 rs13386385 chr2:42436928 G/T cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2014572 0.967 rs10427146 chr19:57755998 T/C cg24459738 chr19:57751996 ZNF805 -0.55 -5.5 -0.44 2.1e-7 Hyperactive-impulsive symptoms; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg12419862 chr22:24373484 LOC391322 -0.63 -6.16 -0.48 9.46e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.791 rs10033211 chr4:98995624 T/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.931 rs7430198 chr3:48988760 T/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.5 0.44 2.06e-7 Parkinson's disease; TGCT cis rs250677 0.652 rs36045 chr5:148441184 A/G cg18129178 chr5:148520854 ABLIM3 0.42 5.7 0.46 8.4e-8 Breast cancer; TGCT cis rs28595532 0.920 rs56162974 chr4:119742333 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7772486 0.875 rs13204280 chr6:146415368 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs6132835 chr20:25434667 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2645424 0.530 rs1293303 chr8:11720227 C/G cg18999641 chr8:11876646 NA -0.21 -4.48 -0.37 1.71e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs4233949 0.535 rs11125534 chr2:54620866 G/T cg14634210 chr2:54682758 SPTBN1 0.5 4.54 0.38 1.34e-5 Bone mineral density; TGCT cis rs2224391 0.628 rs2753236 chr6:5252214 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.74 -0.52 5.44e-10 Height; TGCT cis rs8070740 0.898 rs11078562 chr17:5326857 A/T cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs6424115 1.000 rs7521961 chr1:24157634 C/T cg15997130 chr1:24165203 NA -0.92 -10.61 -0.69 4.13e-19 Immature fraction of reticulocytes; TGCT cis rs17376456 0.825 rs28705226 chr5:93233135 T/C cg21475434 chr5:93447410 FAM172A 0.7 4.9 0.4 2.96e-6 Diabetic retinopathy; TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg07167872 chr1:205819463 PM20D1 0.68 9.98 0.67 1.4e-17 Menarche (age at onset); TGCT cis rs9581857 0.519 rs9581880 chr13:28105850 C/A cg22138327 chr13:27999177 GTF3A 0.72 4.75 0.39 5.45e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6088590 1.000 rs6120750 chr20:33465289 A/C cg06115741 chr20:33292138 TP53INP2 0.64 5.1 0.42 1.25e-6 Coronary artery disease; TGCT cis rs4820539 0.966 rs2267005 chr22:23461723 A/G cg14186256 chr22:23484241 RTDR1 0.93 11.47 0.72 3.32e-21 Bone mineral density; TGCT cis rs10875746 0.903 rs12313404 chr12:48492048 T/A cg20731937 chr12:48336164 NA 0.63 4.96 0.41 2.24e-6 Longevity (90 years and older); TGCT cis rs7914558 0.933 rs10883814 chr10:104737404 T/C cg15744005 chr10:104629667 AS3MT -0.41 -5.08 -0.42 1.33e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6700896 0.500 rs4655555 chr1:66080269 T/A cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs886126 0.950 rs6490025 chr12:111691081 T/C cg10833066 chr12:111807467 FAM109A 0.33 5.64 0.45 1.07e-7 Coronary heart disease; TGCT cis rs362272 0.505 rs13104157 chr4:3366950 T/C cg22655196 chr4:3374909 RGS12 0.24 4.85 0.4 3.63e-6 Serum sulfate level; TGCT cis rs5769765 0.955 rs5770750 chr22:50276828 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.07 -0.48 1.46e-8 Schizophrenia; TGCT cis rs116095464 0.558 rs62347678 chr5:227496 A/G cg22857025 chr5:266934 NA -0.32 -6.53 -0.51 1.5e-9 Breast cancer; TGCT cis rs7681440 0.728 rs1812923 chr4:90739539 C/A cg14346243 chr4:90757452 SNCA -0.54 -5.1 -0.42 1.24e-6 Dementia with Lewy bodies; TGCT cis rs7659604 0.502 rs4075066 chr4:122684283 T/C cg19748678 chr4:122722346 EXOSC9 -0.52 -5.27 -0.43 5.91e-7 Type 2 diabetes; TGCT cis rs6669384 0.547 rs2745979 chr1:208018219 G/C cg22525895 chr1:207977042 MIR29B2 -0.41 -6.04 -0.48 1.68e-8 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs7208859 0.673 rs3764420 chr17:29164154 A/G cg18442181 chr17:29233375 C17orf42 -0.77 -4.54 -0.38 1.32e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2073300 1.000 rs6106656 chr20:23444301 A/G cg09953122 chr20:23471693 CST8 -0.61 -4.45 -0.37 1.9e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs9894429 0.621 rs9747119 chr17:79607017 A/G cg18240062 chr17:79603768 NPLOC4 0.56 4.92 0.4 2.67e-6 Eye color traits; TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg18402987 chr7:1209562 NA 0.38 4.82 0.4 4.05e-6 Longevity;Endometriosis; TGCT cis rs28595532 0.920 rs55640619 chr4:119761999 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg06238570 chr21:40685208 BRWD1 -0.79 -8.74 -0.62 1.36e-14 Cognitive function; TGCT cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg24531977 chr5:56204891 C5orf35 0.77 7.61 0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg25151919 chr3:44754333 ZNF502 -0.46 -5.31 -0.43 4.79e-7 Depressive symptoms; TGCT cis rs968451 0.813 rs5757614 chr22:39717554 G/T cg17798944 chr22:39715225 SNORD43;RPL3 0.84 8.54 0.61 4.02e-14 Primary biliary cholangitis; TGCT cis rs7267979 1.000 rs6132835 chr20:25434667 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3780378 1.000 rs10815158 chr9:5112844 G/A cg02405213 chr9:5042618 JAK2 -0.65 -8.86 -0.62 7.07e-15 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9926296 0.609 rs4785709 chr16:89796665 G/A cg04287289 chr16:89883240 FANCA -0.65 -6.47 -0.5 2.04e-9 Vitiligo; TGCT cis rs11971779 0.680 rs6962186 chr7:139034806 T/C cg07862535 chr7:139043722 LUC7L2 0.57 4.55 0.38 1.24e-5 Diisocyanate-induced asthma; TGCT cis rs9341808 0.667 rs1408292 chr6:80883906 G/T cg08355045 chr6:80787529 NA 0.31 5.1 0.42 1.26e-6 Sitting height ratio; TGCT cis rs4665809 0.816 rs2384359 chr2:26371364 T/C cg04944784 chr2:26401820 FAM59B -0.69 -6.18 -0.49 8.53e-9 Gut microbiome composition (summer); TGCT cis rs9303401 0.659 rs12602389 chr17:56779778 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs10193935 0.901 rs10169411 chr2:42637749 G/A cg27598129 chr2:42591480 NA -0.37 -5.23 -0.42 7.1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs12142240 0.659 rs111723629 chr1:46853361 G/T cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs7267979 0.932 rs449370 chr20:25451180 A/G cg03522245 chr20:25566470 NINL -0.63 -6.77 -0.52 4.49e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg27535305 chr1:53392650 SCP2 -0.28 -5.36 -0.43 3.92e-7 Monocyte count; TGCT trans rs9951602 0.512 rs1599635 chr18:76643819 G/A cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs4595586 0.525 rs12818844 chr12:39423806 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.5 0.37 1.56e-5 Morning vs. evening chronotype; TGCT cis rs523522 0.962 rs2235218 chr12:120888619 A/C cg12219531 chr12:120966889 COQ5 0.79 6.99 0.53 1.47e-10 High light scatter reticulocyte count; TGCT cis rs6815814 0.898 rs6848423 chr4:38887933 C/T cg02016764 chr4:38805732 TLR1 -0.35 -5.39 -0.44 3.35e-7 Breast cancer; TGCT cis rs4713118 0.513 rs183244 chr6:28031838 C/A cg10876282 chr6:28092338 ZSCAN16 0.5 4.6 0.38 1.01e-5 Parkinson's disease; TGCT cis rs7089973 0.624 rs1359080 chr10:116582419 C/A cg03647239 chr10:116582469 FAM160B1 0.58 5.63 0.45 1.16e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg19570321 chr11:63258214 HRASLS5 0.46 5.25 0.43 6.52e-7 Platelet count; TGCT cis rs6547741 1.000 rs11127071 chr2:27838058 C/A cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs3540 0.574 rs2657946 chr15:90967513 G/C cg22089800 chr15:90895588 ZNF774 0.76 8.15 0.59 3.29e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7209700 0.788 rs12949936 chr17:45372422 A/G cg21624342 chr17:45890973 OSBPL7 0.19 5.16 0.42 9.53e-7 IgG glycosylation; TGCT cis rs6952808 0.792 rs11771973 chr7:1950440 C/G cg22963979 chr7:1858916 MAD1L1 -0.35 -5.31 -0.43 4.8e-7 Bipolar disorder and schizophrenia; TGCT cis rs6690583 0.623 rs898036 chr1:85521904 A/T cg20280350 chr1:85513789 MCOLN3 -0.82 -5.27 -0.43 5.92e-7 Serum sulfate level; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg16325326 chr1:53192061 ZYG11B 0.5 5.56 0.45 1.56e-7 Monocyte count; TGCT cis rs12142240 0.667 rs41293287 chr1:46808852 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs7666738 0.761 rs13136913 chr4:98998031 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs826838 0.935 rs11168761 chr12:38997211 C/A cg26384229 chr12:38710491 ALG10B 1.04 10.61 0.69 4.07e-19 Heart rate; TGCT cis rs7191439 0.858 rs8044367 chr16:88783374 A/G cg27087555 chr16:88793112 FAM38A -0.54 -5.86 -0.47 3.88e-8 Plateletcrit; TGCT cis rs7172809 0.615 rs78021430 chr15:77846082 G/T cg22256960 chr15:77711686 NA -0.45 -4.44 -0.37 1.96e-5 Glucose homeostasis traits; TGCT cis rs951366 1.000 rs4951261 chr1:205717823 A/C cg07157834 chr1:205819609 PM20D1 -0.33 -4.61 -0.38 9.98e-6 Menarche (age at onset); TGCT cis rs7727544 0.735 rs274568 chr5:131713578 C/T cg24060327 chr5:131705240 SLC22A5 0.58 6.47 0.5 2.02e-9 Blood metabolite levels; TGCT cis rs2996428 0.628 rs6667526 chr1:3774603 G/A cg17848003 chr1:3704513 LRRC47 0.18 4.91 0.4 2.81e-6 Red cell distribution width; TGCT cis rs3784262 0.934 rs4646611 chr15:58265083 T/C cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.45 -0.56 1.41e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4237845 0.537 rs59401446 chr12:58259564 G/A cg23860436 chr12:58378763 NA 0.34 4.54 0.38 1.31e-5 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.603 rs10946798 chr6:25781853 T/G cg03517284 chr6:25882590 NA 0.51 5.11 0.42 1.18e-6 Blood metabolite levels; TGCT cis rs6977660 0.714 rs10486365 chr7:19801364 A/G cg05791153 chr7:19748676 TWISTNB 0.74 4.45 0.37 1.9e-5 Thyroid stimulating hormone; TGCT cis rs1949733 0.958 rs3103069 chr4:8509451 T/G cg11789530 chr4:8429930 ACOX3 -0.65 -5.95 -0.47 2.58e-8 Response to antineoplastic agents; TGCT cis rs7824557 0.806 rs6601574 chr8:11094885 G/A cg21775007 chr8:11205619 TDH -0.5 -4.55 -0.38 1.27e-5 Retinal vascular caliber; TGCT cis rs1008375 1.000 rs4698641 chr4:17642630 C/T cg18681998 chr4:17616180 MED28 1.02 12.01 0.73 1.65e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9902453 0.874 rs11653805 chr17:28378276 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg02458000 chr6:26745757 NA 0.51 4.66 0.39 8.19e-6 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.559 rs6060857 chr20:30300222 A/G cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs7668190 0.924 rs28622224 chr4:55088093 C/T cg17187183 chr4:55093834 PDGFRA 0.43 6.2 0.49 7.85e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 0.647 rs12440511 chr15:76993135 A/G cg22467129 chr15:76604101 ETFA 0.46 4.6 0.38 1.05e-5 Blood metabolite levels; TGCT cis rs12042938 0.600 rs1865225 chr1:231763004 A/G cg04892437 chr1:231737901 TSNAX-DISC1 -0.45 -4.68 -0.39 7.42e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs11264213 0.686 rs625306 chr1:36454016 T/C cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs9486719 0.948 rs2499817 chr6:96878321 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs17221829 0.645 rs9804648 chr11:89375840 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs2933343 0.621 rs728838 chr3:128589013 A/G cg11901034 chr3:128598214 ACAD9 -0.63 -6.2 -0.49 7.62e-9 IgG glycosylation; TGCT cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9303401 0.538 rs3785493 chr17:56472119 G/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.56 -5.11 -0.42 1.21e-6 Cognitive test performance; TGCT cis rs2730245 0.527 rs2527202 chr7:158738849 T/C cg11984989 chr7:158649758 WDR60 -0.96 -6.98 -0.53 1.61e-10 Height; TGCT cis rs1997103 1.000 rs9642580 chr7:55400359 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs10507380 0.766 rs79754516 chr13:27925487 G/T cg25543773 chr13:27185723 WASF3 0.32 4.52 0.38 1.45e-5 Electrocardiographic traits; TGCT cis rs12360000 0.832 rs12761504 chr10:1907561 C/A cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs4455778 0.600 rs4404870 chr7:49078959 G/A cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs478304 0.651 rs11227299 chr11:65549570 C/G cg27068330 chr11:65405492 SIPA1 -0.95 -9.33 -0.64 5.13e-16 Acne (severe); TGCT cis rs514406 0.683 rs10157120 chr1:53210888 A/G cg01802117 chr1:53393560 SCP2 -0.42 -5.01 -0.41 1.87e-6 Monocyte count; TGCT cis rs5769707 0.642 rs4824070 chr22:50031521 T/C cg06623630 chr22:50017776 C22orf34 -0.27 -4.56 -0.38 1.22e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9309473 0.615 rs62153183 chr2:73763366 A/G cg07208825 chr2:73871855 ALMS1P 0.26 4.87 0.4 3.31e-6 Metabolite levels; TGCT cis rs6671200 0.607 rs3767315 chr1:95705972 A/G cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT trans rs1814175 0.645 rs4411280 chr11:49962750 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs951366 0.903 rs823114 chr1:205719532 G/A cg14893161 chr1:205819251 PM20D1 0.37 4.54 0.38 1.31e-5 Menarche (age at onset); TGCT cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg20607798 chr8:58055168 NA 0.61 5.06 0.41 1.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs7726839 0.540 rs74553517 chr5:665671 C/T cg09021430 chr5:549028 NA -0.4 -5.64 -0.45 1.08e-7 Obesity-related traits; TGCT cis rs12220898 0.749 rs4297382 chr10:50471555 G/A cg25968469 chr10:49687287 ARHGAP22 -0.28 -4.51 -0.38 1.51e-5 Inflammatory biomarkers; TGCT cis rs7017914 0.934 rs6992879 chr8:71699283 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs2688608 0.592 rs11000760 chr10:75493734 G/A cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs11031096 0.679 rs12292515 chr11:4206385 T/G cg18678763 chr11:4115507 RRM1 -0.45 -5.84 -0.46 4.31e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs12497850 0.764 rs6784111 chr3:49178846 T/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.4 0.44 3.31e-7 Parkinson's disease; TGCT cis rs4642101 0.640 rs12629398 chr3:12826799 A/G cg05775895 chr3:12838266 CAND2 0.92 11.28 0.71 9.6e-21 QRS complex (12-leadsum); TGCT cis rs8078723 1.000 rs4795416 chr17:38158133 C/T cg17467752 chr17:38218738 THRA 0.55 5.34 0.43 4.24e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs8177253 0.896 rs34252038 chr3:133490621 G/T cg01448562 chr3:133502909 NA -0.33 -6.79 -0.52 4.13e-10 Iron status biomarkers; TGCT cis rs7223966 1.000 rs9747164 chr17:61864787 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg19318889 chr4:1322082 MAEA 0.19 4.58 0.38 1.13e-5 Longevity; TGCT cis rs262150 0.837 rs2657404 chr7:158783155 C/T cg19418458 chr7:158789849 NA -0.45 -4.69 -0.39 7.16e-6 Facial morphology (factor 20); TGCT cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg06238570 chr21:40685208 BRWD1 -0.8 -9.02 -0.63 2.92e-15 Cognitive function; TGCT cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -1.04 -14.28 -0.79 5.95e-28 Menarche (age at onset); TGCT cis rs6998277 1.000 rs16869658 chr8:103633762 C/T cg10187029 chr8:103597600 NA 0.43 5.44 0.44 2.76e-7 Migraine; TGCT cis rs9650657 0.615 rs7818181 chr8:10696515 C/T cg16664915 chr8:10907788 XKR6 -0.29 -4.69 -0.39 7.01e-6 Neuroticism; TGCT cis rs7659604 0.840 rs6821305 chr4:122713863 A/C cg06713675 chr4:122721982 EXOSC9 -0.48 -6.12 -0.48 1.14e-8 Type 2 diabetes; TGCT cis rs9911578 0.967 rs405684 chr17:56777148 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7940866 1.000 rs7940866 chr11:130817579 A/T cg12179176 chr11:130786555 SNX19 -0.59 -5.53 -0.44 1.81e-7 Schizophrenia; TGCT cis rs185694 1.000 rs202098 chr13:30896774 G/T cg07600127 chr13:30881527 KATNAL1 -0.82 -6.64 -0.51 8.92e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs7312933 0.618 rs7315968 chr12:42637086 G/A cg19980929 chr12:42632907 YAF2 0.41 5.86 0.47 3.85e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs116095464 1.000 rs28416084 chr5:217640 G/A cg12570787 chr5:219185 SDHA;CCDC127 0.71 4.75 0.39 5.44e-6 Breast cancer; TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg24675658 chr1:53192096 ZYG11B -0.78 -9.21 -0.64 1.01e-15 Monocyte count; TGCT cis rs10782582 0.609 rs5745410 chr1:76314356 C/A cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs12681288 0.862 rs7814231 chr8:1021103 A/G cg04851639 chr8:1020857 NA -0.37 -6.84 -0.52 3.27e-10 Schizophrenia; TGCT cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg11890956 chr21:40555474 PSMG1 1.1 11.97 0.73 2e-22 Cognitive function; TGCT cis rs7666738 0.830 rs7674095 chr4:99048158 T/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs911555 0.504 rs745079 chr14:104073551 G/A cg26031613 chr14:104095156 KLC1 0.61 5.6 0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs8072100 0.837 rs62074055 chr17:45771933 G/C cg08085267 chr17:45401833 C17orf57 -0.44 -5.16 -0.42 9.69e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7833790 0.700 rs7825180 chr8:82723991 T/A cg23324259 chr8:82754387 SNX16 -0.61 -4.71 -0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs5769765 0.818 rs8140681 chr22:50292081 C/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.86 -0.73 3.71e-22 Schizophrenia; TGCT cis rs9682041 0.877 rs10804841 chr3:170072031 T/A cg07589077 chr3:170072950 NA 0.29 5.15 0.42 1e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs6496667 0.533 rs2074584 chr15:91009381 C/T cg22089800 chr15:90895588 ZNF774 0.51 4.44 0.37 1.97e-5 Rheumatoid arthritis; TGCT cis rs514406 0.861 rs503296 chr1:53283088 A/G cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.84 10.12 0.67 6.47e-18 Prudent dietary pattern; TGCT cis rs896854 0.654 rs13278601 chr8:95972974 G/C cg16049864 chr8:95962084 TP53INP1 -0.75 -10.47 -0.69 9.05e-19 Type 2 diabetes; TGCT cis rs7246657 1.000 rs7246657 chr19:37747108 C/T cg03233940 chr19:37894644 NA 0.37 4.79 0.39 4.73e-6 Coronary artery calcification; TGCT cis rs9300255 0.537 rs1790101 chr12:123704844 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs9368481 0.761 rs4358615 chr6:26998567 A/G cg26531700 chr6:26746687 NA 0.55 5.18 0.42 8.89e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2797160 0.904 rs2326292 chr6:125999674 G/A cg05901451 chr6:126070800 HEY2 -0.78 -6.85 -0.52 3.01e-10 Endometrial cancer; TGCT cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg18305652 chr10:134549665 INPP5A 0.35 5.69 0.45 8.83e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2880765 0.835 rs4842884 chr15:86035174 T/C cg13263323 chr15:86062960 AKAP13 -0.22 -4.79 -0.4 4.68e-6 Coronary artery disease; TGCT cis rs11696501 0.688 rs6130894 chr20:44322673 G/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs12477438 0.501 rs12992218 chr2:99753834 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs10892173 0.566 rs10892175 chr11:117674355 G/A cg21640587 chr11:117668038 DSCAML1 0.71 8.19 0.59 2.74e-13 Myopia; TGCT cis rs916888 0.821 rs199504 chr17:44861003 C/T cg17911788 chr17:44343683 NA 0.58 6.01 0.47 1.93e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg02458000 chr6:26745757 NA 0.5 4.52 0.38 1.4e-5 Intelligence (multi-trait analysis); TGCT cis rs7226408 0.817 rs55766643 chr18:34448069 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs908922 0.651 rs1337341 chr1:152508259 A/C cg20991723 chr1:152506922 NA 0.46 6.08 0.48 1.36e-8 Hair morphology; TGCT cis rs5769707 0.521 rs6009810 chr22:50059540 A/G cg05373962 chr22:49881684 NA -0.32 -5.41 -0.44 3.16e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10489202 0.632 rs413168 chr1:168005789 C/G cg24449463 chr1:168025552 DCAF6 -0.6 -7.13 -0.54 7.21e-11 Schizophrenia; TGCT cis rs12200560 0.505 rs211178 chr6:97074094 T/A cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs7833790 0.963 rs28823280 chr8:82777716 G/A cg27398817 chr8:82754497 SNX16 0.8 6.08 0.48 1.39e-8 Diastolic blood pressure; TGCT cis rs3733631 0.947 rs1351623 chr4:104587977 C/T cg24090629 chr4:104641072 TACR3 -0.71 -5.56 -0.45 1.55e-7 Menarche (age at onset); TGCT cis rs2228479 0.681 rs7196840 chr16:89959647 A/G cg06558623 chr16:89946397 TCF25 0.42 5.07 0.41 1.38e-6 Skin colour saturation; TGCT cis rs9952991 0.941 rs34920518 chr18:12783086 A/G cg24737193 chr18:12778029 NA -0.52 -5.57 -0.45 1.51e-7 Inflammatory skin disease; TGCT trans rs10953454 1.000 rs12705282 chr7:104488143 G/A cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs4819052 1.000 rs3746980 chr21:46711580 C/T cg06618935 chr21:46677482 NA -0.38 -4.94 -0.41 2.51e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2120019 0.938 rs8040169 chr15:75370958 C/A cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs10504229 0.679 rs12679920 chr8:58051710 G/T cg08280861 chr8:58055591 NA 0.39 5.61 0.45 1.26e-7 Developmental language disorder (linguistic errors); TGCT cis rs6088580 0.634 rs6088512 chr20:33095891 G/A cg06115741 chr20:33292138 TP53INP2 0.53 4.65 0.39 8.41e-6 Glomerular filtration rate (creatinine); TGCT cis rs7715806 0.500 rs58968428 chr5:75004107 A/G cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs79387448 0.745 rs74560841 chr2:103149210 G/A cg09003973 chr2:102972529 NA 1.1 7.22 0.54 4.67e-11 Gut microbiota (bacterial taxa); TGCT cis rs4665809 1.000 rs4233708 chr2:26291345 C/T cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs9640161 0.663 rs56402329 chr7:149998426 A/G cg10018233 chr7:150070692 REPIN1 0.33 4.52 0.38 1.43e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs11247915 0.600 rs61775118 chr1:26659692 C/T cg01414934 chr1:26605969 SH3BGRL3 0.21 4.51 0.38 1.48e-5 Obesity-related traits; TGCT cis rs1153858 1.000 rs1980288 chr15:45620612 T/C cg26924012 chr15:45694286 SPATA5L1 1.07 14.49 0.79 1.89e-28 Homoarginine levels; TGCT cis rs875971 0.660 rs1860468 chr7:66107252 T/C cg18876405 chr7:65276391 NA -0.37 -5.58 -0.45 1.47e-7 Aortic root size; TGCT cis rs12971120 0.947 rs8084109 chr18:72168312 T/A cg25817165 chr18:72167213 CNDP2 -0.29 -5.54 -0.45 1.71e-7 Refractive error; TGCT cis rs56309584 0.715 rs74252612 chr17:8142100 G/A cg08322244 chr17:8066669 VAMP2 -0.57 -5.26 -0.43 6.01e-7 Initial pursuit acceleration; TGCT cis rs6988636 1.000 rs11992152 chr8:124189455 T/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs67478160 0.643 rs2295145 chr14:104202304 G/A cg26031613 chr14:104095156 KLC1 -0.67 -7.15 -0.54 6.67e-11 Schizophrenia; TGCT cis rs4727027 0.933 rs62505074 chr7:148834780 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1577917 0.916 rs4142546 chr6:86505311 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs79839061 0.732 rs73207773 chr4:827249 G/A cg07828340 chr4:882639 GAK 0.4 5.03 0.41 1.71e-6 Intelligence (multi-trait analysis); TGCT cis rs3782089 1.000 rs3782089 chr11:65336819 C/T cg21890820 chr11:65308645 LTBP3 0.89 5.38 0.43 3.6e-7 Height; TGCT cis rs7654585 0.645 rs6828416 chr4:25933273 C/T cg10409131 chr4:25915609 C4orf52 0.75 7.02 0.53 1.27e-10 Obesity-related traits; TGCT cis rs7017914 0.902 rs35893260 chr8:71620073 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs6840360 0.533 rs11099829 chr4:152727299 A/G cg22705602 chr4:152727874 NA 0.33 5.99 0.47 2.13e-8 Intelligence (multi-trait analysis); TGCT cis rs3771570 0.892 rs55751610 chr2:242346057 C/T cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.97e-10 Prostate cancer; TGCT cis rs67072384 1.000 rs12271961 chr11:72453596 G/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs1843834 0.539 rs3912999 chr2:225390089 C/T cg12698349 chr2:225449008 CUL3 0.81 6.81 0.52 3.78e-10 IgE levels in asthmatics (D.p. specific); TGCT cis rs3784262 0.740 rs4646596 chr15:58300895 G/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.28 -0.49 5.12e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs10170846 0.626 rs9288575 chr2:223495133 A/C cg25565276 chr2:223520875 FARSB 1.04 8.17 0.59 2.94e-13 Schizophrenia (inflammation and infection response interaction); TGCT cis rs1218582 0.772 rs12069356 chr1:154849771 C/T cg06221963 chr1:154839813 KCNN3 -0.74 -13.38 -0.77 7.94e-26 Prostate cancer; TGCT cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs2832191 0.720 rs2832200 chr21:30499165 G/A cg24692254 chr21:30365293 RNF160 -0.86 -9.11 -0.63 1.83e-15 Dental caries; TGCT cis rs3812831 0.629 rs7318527 chr13:114946956 C/T cg08824895 chr13:115047677 UPF3A 0.49 4.73 0.39 5.98e-6 Schizophrenia; TGCT cis rs1800469 0.965 rs11668109 chr19:41863777 A/C cg09537434 chr19:41945824 ATP5SL -0.53 -4.76 -0.39 5.23e-6 Colorectal cancer; TGCT cis rs9300255 0.620 rs7313483 chr12:123726834 C/T cg00376283 chr12:123451042 ABCB9 0.72 5.52 0.44 1.88e-7 Neutrophil percentage of white cells; TGCT cis rs7582180 0.564 rs2309795 chr2:100954290 G/A cg14675211 chr2:100938903 LONRF2 0.53 5.16 0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs617219 0.671 rs1062326 chr5:78617534 A/C cg23987322 chr5:78407566 BHMT -0.35 -4.51 -0.38 1.49e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs425277 1.000 rs262651 chr1:2091397 A/G cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs6933660 0.745 rs9322320 chr6:151751908 C/G cg10883421 chr6:151773342 RMND1;C6orf211 0.64 6.4 0.5 2.87e-9 Menarche (age at onset); TGCT cis rs2742417 1.000 rs1969626 chr3:45746836 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg02675527 chr2:114030824 PAX8;LOC440839 -0.52 -6.89 -0.53 2.52e-10 Lymphocyte counts; TGCT cis rs709400 0.633 rs2296484 chr14:104003094 C/T cg26031613 chr14:104095156 KLC1 0.89 9.8 0.66 3.77e-17 Body mass index; TGCT cis rs12220238 0.841 rs10824163 chr10:76136589 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.87 6.32 0.49 4.31e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3617 0.573 rs9860296 chr3:52913781 A/G cg11645453 chr3:52864694 ITIH4 0.28 5.35 0.43 4.08e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9291683 0.551 rs2276961 chr4:10022981 C/T cg00071950 chr4:10020882 SLC2A9 0.7 9.52 0.65 1.86e-16 Bone mineral density; TGCT cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg00343986 chr7:65444356 GUSB -0.25 -5.81 -0.46 4.89e-8 Aortic root size; TGCT cis rs433598 0.704 rs163267 chr16:20660957 T/A cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -5.08 -0.42 1.34e-6 Schizophrenia; TGCT cis rs12477438 0.765 rs1115756 chr2:99659845 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs1555895 0.566 rs1000278 chr10:852629 C/T cg02193355 chr10:851439 NA 0.25 5.6 0.45 1.3e-7 Survival in rectal cancer; TGCT cis rs1018836 0.608 rs6992512 chr8:91477936 C/A cg16814680 chr8:91681699 NA -0.71 -7.14 -0.54 6.85e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4642101 0.640 rs3901666 chr3:12824363 G/T cg05775895 chr3:12838266 CAND2 -0.67 -6.96 -0.53 1.77e-10 QRS complex (12-leadsum); TGCT cis rs12220898 0.679 rs4838483 chr10:50481870 G/A cg06072769 chr10:50146962 WDFY4 0.38 4.98 0.41 2.07e-6 Inflammatory biomarkers; TGCT cis rs7772486 0.688 rs1884364 chr6:146337817 C/G cg13319975 chr6:146136371 FBXO30 -0.65 -6.07 -0.48 1.47e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs11690935 0.959 rs76324055 chr2:172620150 T/A cg13550731 chr2:172543902 DYNC1I2 -1.2 -12.28 -0.74 3.49e-23 Schizophrenia; TGCT cis rs10276381 1.000 rs10280937 chr7:28182306 T/C cg23620719 chr7:28220237 JAZF1 0.99 5.75 0.46 6.58e-8 Crohn's disease; TGCT trans rs1005277 0.505 rs200935 chr10:38132810 T/A cg17830980 chr10:43048298 ZNF37B -0.72 -8.22 -0.59 2.33e-13 Extrinsic epigenetic age acceleration; TGCT cis rs854765 0.647 rs2955365 chr17:18023897 G/A cg04398451 chr17:18023971 MYO15A -0.39 -6.89 -0.53 2.53e-10 Total body bone mineral density; TGCT cis rs2562456 0.917 rs2681376 chr19:21715525 T/G cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs739496 0.947 rs739497 chr12:111858086 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs548987 0.507 rs35875210 chr6:25827484 A/G cg03264133 chr6:25882463 NA -0.54 -4.44 -0.37 1.99e-5 Homocysteine levels; TGCT cis rs7264396 0.790 rs2207889 chr20:34224898 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.68 -0.39 7.38e-6 Total cholesterol levels; TGCT cis rs875971 0.862 rs2420174 chr7:65645361 C/T cg11764359 chr7:65958608 NA -0.56 -5.04 -0.41 1.61e-6 Aortic root size; TGCT cis rs2832191 0.720 rs2832200 chr21:30499165 G/A cg08807101 chr21:30365312 RNF160 -0.62 -5.8 -0.46 5.14e-8 Dental caries; TGCT cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.52 -5.85 -0.47 4.02e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs7829975 0.714 rs4841042 chr8:8664622 A/G cg08975724 chr8:8085496 FLJ10661 -0.55 -5.04 -0.41 1.59e-6 Mood instability; TGCT cis rs1784581 0.588 rs1784583 chr6:162410132 C/T cg17173639 chr6:162384350 PARK2 -0.4 -6.67 -0.51 7.39e-10 Itch intensity from mosquito bite; TGCT cis rs11098499 0.954 rs12510138 chr4:120423935 C/G cg09307838 chr4:120376055 NA 0.67 6.34 0.49 3.87e-9 Corneal astigmatism; TGCT cis rs72949976 1.000 rs62186569 chr2:214034151 C/T cg08319019 chr2:214017104 IKZF2 -0.79 -7.3 -0.55 2.97e-11 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs78487399 0.808 rs17030998 chr2:43758199 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9467773 0.838 rs3734540 chr6:26463321 A/C cg26531700 chr6:26746687 NA 0.55 5.47 0.44 2.34e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.822 rs28367231 chr4:98845726 G/T cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.79e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 1.000 rs2215450 chr4:17675394 T/G cg10189774 chr4:17578691 LAP3 0.57 5.25 0.43 6.37e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs17253792 0.822 rs111467375 chr14:56046159 T/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs933688 1.000 rs12655973 chr5:90736537 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.98 8.79 0.62 1.02e-14 Smoking behavior; TGCT cis rs11874712 0.965 rs12954944 chr18:43664115 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs2046867 0.818 rs1502757 chr3:72864161 C/T cg25664220 chr3:72788482 NA -0.56 -7.03 -0.53 1.24e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs17685 0.712 rs1859792 chr7:75789264 T/C cg19862616 chr7:65841803 NCRNA00174 0.53 9.13 0.63 1.6e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6463523 0.933 rs4724821 chr7:762544 C/T cg27302301 chr7:1268188 NA 0.3 4.54 0.38 1.32e-5 Subjective well-being; TGCT cis rs4820539 1.000 rs4822357 chr22:23473231 A/G cg21100191 chr22:23484243 RTDR1 0.94 8.9 0.62 5.74e-15 Bone mineral density; TGCT cis rs7412746 0.611 rs111905669 chr1:150777565 T/C cg04414720 chr1:150670196 GOLPH3L 0.41 5.07 0.41 1.41e-6 Melanoma; TGCT trans rs6089829 0.855 rs6090205 chr20:61665269 A/G cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs6089829 0.926 rs6011552 chr20:61667894 T/C cg08045932 chr20:61659980 NA 0.47 8.81 0.62 9.31e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs4665809 1.000 rs6546727 chr2:26275282 C/T cg22920501 chr2:26401640 FAM59B -0.74 -6.45 -0.5 2.32e-9 Gut microbiome composition (summer); TGCT cis rs10489202 0.632 rs149912 chr1:167957803 A/T cg24449463 chr1:168025552 DCAF6 -0.58 -6.83 -0.52 3.35e-10 Schizophrenia; TGCT cis rs10501293 0.709 rs7943878 chr11:43006269 T/C cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.2e-9 Cognitive performance; TGCT cis rs2580764 0.598 rs6755468 chr2:55240026 A/C cg09592903 chr2:55203963 RTN4 -0.27 -5.92 -0.47 3e-8 Mean platelet volume; TGCT cis rs9814567 1.000 rs55913793 chr3:134285968 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.18 -0.64 1.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1670533 1.000 rs6858612 chr4:1053353 C/T cg27284194 chr4:1044797 NA 0.67 5.97 0.47 2.29e-8 Recombination rate (females); TGCT cis rs9640161 0.830 rs36069544 chr7:150061538 G/A cg21361702 chr7:150065534 REPIN1 0.5 4.56 0.38 1.2e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs10904908 0.733 rs7080366 chr10:17254832 C/T cg01003015 chr10:17271136 VIM -0.55 -4.8 -0.4 4.39e-6 Total cholesterol levels;Cholesterol, total; TGCT cis rs7647973 1.000 rs7613491 chr3:49508976 T/C cg06212747 chr3:49208901 KLHDC8B -0.59 -4.67 -0.39 7.6e-6 Menarche (age at onset); TGCT cis rs1008375 0.966 rs7675735 chr4:17587137 T/A cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs17685 0.712 rs10275521 chr7:75770972 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs5769707 0.681 rs1107514 chr22:50042383 T/C cg05373962 chr22:49881684 NA -0.34 -5.66 -0.45 1.01e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1552244 0.882 rs13099136 chr3:10031431 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs1018836 0.923 rs2157607 chr8:91600268 A/G cg16814680 chr8:91681699 NA -0.83 -8.74 -0.62 1.33e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg10802521 chr3:52805072 NEK4 -0.62 -7.17 -0.54 5.94e-11 Electroencephalogram traits; TGCT cis rs7666738 0.830 rs6839203 chr4:98839814 C/G cg17366294 chr4:99064904 C4orf37 0.72 7.5 0.56 1.07e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg06481639 chr22:41940642 POLR3H -0.61 -5.49 -0.44 2.17e-7 Vitiligo; TGCT cis rs9677476 0.863 rs12478335 chr2:232064967 C/A cg07929768 chr2:232055508 NA 0.31 4.49 0.37 1.61e-5 Food antigen IgG levels; TGCT cis rs5167 0.533 rs11083755 chr19:45490065 C/T cg13119609 chr19:45449297 APOC2 0.23 4.65 0.39 8.26e-6 Blood protein levels; TGCT cis rs28595532 0.920 rs114243409 chr4:119756585 C/A cg21605333 chr4:119757512 SEC24D 1.62 7.73 0.57 3.22e-12 Cannabis dependence symptom count; TGCT cis rs9467773 1.000 rs28558133 chr6:26531433 G/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs13064447 0.967 rs55668390 chr3:12766020 C/G cg20675869 chr3:12750130 NA -0.19 -4.81 -0.4 4.28e-6 Major depression and alcohol dependence; TGCT cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs7216064 1.000 rs73352808 chr17:65875157 G/A cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1046896 0.552 rs12602280 chr17:80805421 G/C cg03160526 chr17:80928410 B3GNTL1 0.33 4.57 0.38 1.18e-5 Glycated hemoglobin levels; TGCT cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg11062466 chr8:58055876 NA 0.38 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs6740322 0.895 rs6710656 chr2:43566941 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.43 -0.5 2.44e-9 Coronary artery disease; TGCT cis rs7178572 0.568 rs4886515 chr15:77686886 G/A cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs4665809 1.000 rs10170359 chr2:26272219 G/T cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 1.99e-6 Gut microbiome composition (summer); TGCT cis rs9910055 0.540 rs609292 chr17:42180436 G/A cg13607699 chr17:42295918 UBTF -0.61 -5.09 -0.42 1.32e-6 Total body bone mineral density; TGCT cis rs308403 0.600 rs309366 chr4:123661408 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.73 6.85 0.52 3e-10 Blood protein levels; TGCT cis rs2832191 0.740 rs2832177 chr21:30478353 G/A cg24692254 chr21:30365293 RNF160 -1.01 -11.59 -0.72 1.73e-21 Dental caries; TGCT cis rs7107174 0.681 rs11237443 chr11:78005089 C/A cg12700464 chr11:78128424 GAB2 -0.67 -4.63 -0.38 8.98e-6 Testicular germ cell tumor; TGCT cis rs36051895 0.588 rs12340895 chr9:5076691 C/G cg02405213 chr9:5042618 JAK2 0.73 9.28 0.64 6.85e-16 Pediatric autoimmune diseases; TGCT cis rs9952991 0.608 rs9960807 chr18:12770851 A/G cg23544223 chr18:12777786 NA -0.61 -4.64 -0.38 8.63e-6 Inflammatory skin disease; TGCT cis rs394563 0.591 rs11155641 chr6:149648595 G/A cg11245181 chr6:149772854 ZC3H12D 0.28 4.64 0.38 8.68e-6 Dupuytren's disease; TGCT cis rs7552404 0.731 rs11588578 chr1:76400539 T/G cg10523679 chr1:76189770 ACADM 0.82 7.13 0.54 7.47e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9611565 0.765 rs132906 chr22:41799767 G/C cg13695892 chr22:41940480 POLR3H 0.74 7.39 0.55 1.92e-11 Vitiligo; TGCT cis rs644148 0.770 rs2571113 chr19:44999814 A/G cg15540054 chr19:45004280 ZNF180 -0.65 -5.33 -0.43 4.48e-7 Personality dimensions; TGCT cis rs138880 0.505 rs56248708 chr22:50306969 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.2 -7.39 -0.55 1.9e-11 Schizophrenia; TGCT trans rs4295623 0.504 rs11250160 chr8:11592717 G/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.76 -0.52 4.93e-10 Morning vs. evening chronotype; TGCT cis rs36051895 0.623 rs1555476 chr9:5233054 T/C cg02405213 chr9:5042618 JAK2 -0.67 -7.85 -0.58 1.66e-12 Pediatric autoimmune diseases; TGCT cis rs1903068 0.853 rs9997685 chr4:56022903 A/T cg09978860 chr4:56023921 NA 0.56 5.9 0.47 3.18e-8 Endometriosis; TGCT cis rs3540 0.597 rs1978149 chr15:91036976 A/G cg22089800 chr15:90895588 ZNF774 0.76 7.77 0.57 2.62e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2033711 0.783 rs8113810 chr19:58932106 A/G cg12042659 chr19:58951599 ZNF132 0.52 4.81 0.4 4.31e-6 Uric acid clearance; TGCT cis rs477895 1.000 rs66968227 chr11:64070930 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.65 4.96 0.41 2.29e-6 Mean platelet volume; TGCT cis rs4601821 0.858 rs7945132 chr11:113262473 A/T cg14159747 chr11:113255604 NA 0.38 4.48 0.37 1.67e-5 Alcoholic chronic pancreatitis; TGCT cis rs11792861 0.781 rs874864 chr9:111728718 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.79 0.4 4.69e-6 Menarche (age at onset); TGCT cis rs112217694 1.000 rs75065217 chr4:104653578 C/T cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs56309584 0.560 rs72479723 chr17:8076741 A/G cg08322244 chr17:8066669 VAMP2 -0.52 -4.89 -0.4 3.04e-6 Initial pursuit acceleration; TGCT cis rs6570726 0.818 rs398812 chr6:145817271 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.61 0.38 9.83e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2075371 1.000 rs2244694 chr7:133987093 C/T cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs12188164 0.762 rs11745923 chr5:475408 T/G cg26850624 chr5:429559 AHRR -0.2 -4.76 -0.39 5.33e-6 Cystic fibrosis severity; TGCT cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.43 -0.44 2.89e-7 Coronary artery disease; TGCT cis rs10992471 0.603 rs4744137 chr9:95288352 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.63 -0.45 1.13e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6882046 0.513 rs651666 chr5:88048767 A/G cg22951263 chr5:87985283 NA -0.58 -6.12 -0.48 1.12e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs904251 0.861 rs1757169 chr6:37487076 G/T cg08126542 chr6:37504118 NA -0.44 -5.92 -0.47 2.96e-8 Cognitive performance; TGCT trans rs6089829 0.855 rs4809459 chr20:61661345 C/T cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs11690935 0.694 rs312921 chr2:172567225 T/C cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.75 -0.75 2.7e-24 Schizophrenia; TGCT cis rs1799949 0.965 rs8070179 chr17:41202688 G/A cg05368731 chr17:41323189 NBR1 0.9 8.95 0.63 4.4e-15 Menopause (age at onset); TGCT cis rs709400 0.567 rs1961600 chr14:103862144 G/A cg12935359 chr14:103987150 CKB -0.36 -5.38 -0.43 3.63e-7 Body mass index; TGCT cis rs9921192 1.000 rs2892165 chr16:4324293 A/T cg00021532 chr16:4324280 TFAP4 0.82 9.35 0.64 4.71e-16 Prostate-specific antigen levels; TGCT cis rs6840360 0.615 rs3828546 chr4:152679816 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.16 -0.42 9.49e-7 Intelligence (multi-trait analysis); TGCT cis rs6678914 0.738 rs721559 chr1:202188119 T/C cg08883485 chr1:201619787 NAV1 -0.38 -4.52 -0.38 1.44e-5 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs6484504 0.576 rs438578 chr11:31222579 A/G cg26647111 chr11:31128758 NA 0.32 4.66 0.39 8e-6 Red blood cell count; TGCT cis rs67478160 0.634 rs941475 chr14:104240618 A/C cg26031613 chr14:104095156 KLC1 -0.64 -6.6 -0.51 1.07e-9 Schizophrenia; TGCT cis rs35306767 0.807 rs12768348 chr10:899224 T/G cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs3749237 0.595 rs10865955 chr3:49499829 G/A cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs6460942 0.908 rs117451929 chr7:12265149 A/T cg06484146 chr7:12443880 VWDE -0.55 -4.63 -0.38 9.11e-6 Coronary artery disease; TGCT cis rs1215050 0.791 rs1215049 chr4:98848280 C/T cg05340658 chr4:99064831 C4orf37 0.45 5.49 0.44 2.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1894292 0.527 rs10212657 chr4:74361254 T/C cg05868023 chr4:75230803 EREG 0.53 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs13256369 0.950 rs13270006 chr8:8574197 C/A cg18904891 chr8:8559673 CLDN23 0.64 5.89 0.47 3.36e-8 Obesity-related traits; TGCT cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2268241 0.938 rs2300373 chr21:34788739 A/T cg14850771 chr21:34775459 IFNGR2 0.61 4.9 0.4 2.93e-6 Obesity-related traits; TGCT cis rs7539409 0.604 rs6689821 chr1:84316605 A/G cg10977910 chr1:84465055 TTLL7 0.88 5.62 0.45 1.19e-7 Alzheimer's disease; TGCT cis rs6545883 0.894 rs2600660 chr2:61549600 G/T cg15711740 chr2:61764176 XPO1 0.55 4.72 0.39 6.38e-6 Tuberculosis; TGCT cis rs208520 0.909 rs9345809 chr6:67017543 T/C cg07460842 chr6:66804631 NA 0.73 5.91 0.47 3.07e-8 Exhaled nitric oxide output; TGCT cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg10047753 chr17:41438598 NA 0.97 9.91 0.66 2.09e-17 Menopause (age at onset); TGCT cis rs74233809 1.000 rs77180047 chr10:104666757 G/A cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs4665809 1.000 rs12475854 chr2:26267375 G/A cg25036284 chr2:26402008 FAM59B -0.55 -4.76 -0.39 5.33e-6 Gut microbiome composition (summer); TGCT cis rs1541995 0.898 rs12901540 chr15:96332408 T/A cg00882281 chr15:96346592 NA 0.27 4.45 0.37 1.86e-5 Photic sneeze reflex; TGCT cis rs593982 0.843 rs680948 chr11:65472394 C/G cg08755490 chr11:65554678 OVOL1 1.29 7.51 0.56 1.02e-11 Atopic dermatitis; TGCT cis rs5769707 0.542 rs739242 chr22:50057116 A/G cg05373962 chr22:49881684 NA -0.32 -5.46 -0.44 2.46e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6750047 0.756 rs4670233 chr2:38272342 A/G cg07380506 chr2:38303506 CYP1B1 0.58 5.34 0.43 4.24e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs9733 0.519 rs11807450 chr1:150677719 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.89 0.4 3.05e-6 Tonsillectomy; TGCT cis rs9311474 0.607 rs34005367 chr3:52558904 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.74 0.52 5.28e-10 Electroencephalogram traits; TGCT cis rs6570726 0.818 rs9390338 chr6:145908265 A/G cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9902453 0.967 rs12450956 chr17:28529025 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.4 0.44 3.24e-7 Coffee consumption (cups per day); TGCT cis rs9581857 0.685 rs60787915 chr13:28022298 C/T cg22138327 chr13:27999177 GTF3A 0.68 4.9 0.4 2.87e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6977660 0.714 rs10249635 chr7:19787090 A/G cg05791153 chr7:19748676 TWISTNB 0.84 4.73 0.39 5.91e-6 Thyroid stimulating hormone; TGCT trans rs9650657 0.571 rs4240673 chr8:10787612 T/C cg15556689 chr8:8085844 FLJ10661 -0.78 -6.94 -0.53 1.94e-10 Neuroticism; TGCT cis rs79839061 0.520 rs2279187 chr4:875529 C/T cg15843217 chr4:699224 PCGF3 -0.63 -4.5 -0.37 1.55e-5 Intelligence (multi-trait analysis); TGCT cis rs10479542 0.892 rs7736163 chr5:178980316 G/C cg19723775 chr5:179050963 HNRNPH1 0.53 5.29 0.43 5.29e-7 Lung cancer; TGCT cis rs10493773 0.775 rs2069208 chr1:86117583 T/C cg17807903 chr1:86174739 ZNHIT6 -0.44 -6.34 -0.49 3.83e-9 Urate levels in overweight individuals; TGCT cis rs34042186 1 rs34042186 chr3:46462909 G/A cg15561453 chr3:47459664 SCAP 0.31 4.52 0.38 1.41e-5 Monocyte percentage of white cells; TGCT cis rs7824557 0.547 rs2409749 chr8:11078949 G/A cg21775007 chr8:11205619 TDH -0.49 -4.48 -0.37 1.66e-5 Retinal vascular caliber; TGCT cis rs739496 0.527 rs2269803 chr12:112326145 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.69e-8 Platelet count; TGCT cis rs10193935 0.901 rs10171643 chr2:42532912 C/T cg27598129 chr2:42591480 NA -0.42 -6.05 -0.48 1.61e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12200560 0.505 rs211176 chr6:97073821 G/A cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs11711311 1.000 rs9830975 chr3:113486019 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs4783244 0.862 rs4782721 chr16:82656995 A/G cg09415485 chr16:82663111 CDH13 0.24 4.61 0.38 9.73e-6 Adiponectin levels; TGCT cis rs682748 1.000 rs587006 chr5:17148502 G/A cg23987134 chr5:17158319 LOC285696 -0.23 -5.42 -0.44 2.93e-7 Hippocampal atrophy; TGCT cis rs899997 1.000 rs7182993 chr15:79045014 G/A cg00061860 chr15:78953028 NA -0.27 -4.67 -0.39 7.62e-6 Coronary artery disease or large artery stroke; TGCT cis rs72843506 0.722 rs76309839 chr17:20175460 T/C cg18979559 chr17:20280153 CCDC144C -0.65 -4.88 -0.4 3.2e-6 Schizophrenia; TGCT cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg09323728 chr8:95962352 TP53INP1 -0.51 -6.5 -0.5 1.74e-9 Type 2 diabetes; TGCT cis rs7100689 0.646 rs7903701 chr10:82129268 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs9300255 0.596 rs10773002 chr12:123746961 A/T cg00376283 chr12:123451042 ABCB9 -0.72 -5.77 -0.46 6.1e-8 Neutrophil percentage of white cells; TGCT cis rs62244186 0.659 rs9311358 chr3:44538748 C/G cg04389838 chr3:44770851 ZNF501 -0.38 -4.92 -0.4 2.66e-6 Depressive symptoms; TGCT cis rs10267417 0.544 rs2072185 chr7:19748700 G/A cg07541023 chr7:19748670 TWISTNB 1.21 11.01 0.7 4.36e-20 Night sleep phenotypes; TGCT cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs9611565 0.559 rs6002408 chr22:41967870 C/T cg06481639 chr22:41940642 POLR3H -0.66 -5.64 -0.45 1.12e-7 Vitiligo; TGCT cis rs7584330 0.737 rs1497127 chr2:238369282 A/G cg14458575 chr2:238380390 NA 0.46 7.42 0.55 1.64e-11 Prostate cancer; TGCT cis rs9916302 0.706 rs4516267 chr17:37471482 G/T cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg02487422 chr3:49467188 NICN1 0.5 4.55 0.38 1.24e-5 Parkinson's disease; TGCT cis rs877282 0.898 rs11253341 chr10:765008 G/C cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg06108461 chr20:60628389 TAF4 -0.71 -10.51 -0.69 7.47e-19 Body mass index; TGCT cis rs8038465 0.622 rs17185294 chr15:73858415 C/T cg15420318 chr15:73925796 NPTN -0.62 -6.42 -0.5 2.62e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs317865 0.737 rs16893153 chr4:16181798 T/C cg04764131 chr4:16228633 TAPT1;FLJ39653 0.68 4.49 0.37 1.6e-5 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs514406 0.825 rs28817407 chr1:53226116 G/A cg01802117 chr1:53393560 SCP2 0.43 5.13 0.42 1.1e-6 Monocyte count; TGCT cis rs17345786 0.906 rs72944107 chr3:101197190 C/T cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7681440 0.904 rs3756063 chr4:90757394 G/C cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.91e-8 Dementia with Lewy bodies; TGCT cis rs11690935 1.000 rs6433311 chr2:172549248 A/G cg13550731 chr2:172543902 DYNC1I2 1.21 13.07 0.76 4.43e-25 Schizophrenia; TGCT cis rs4455778 0.659 rs10278618 chr7:49040616 A/C cg26309511 chr7:48887640 NA 0.42 4.98 0.41 2.08e-6 Lung cancer in never smokers; TGCT cis rs1385374 0.858 rs10847696 chr12:129297153 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs7072216 0.727 rs6584199 chr10:100169983 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs7819412 0.522 rs4841497 chr8:10985140 A/G cg21775007 chr8:11205619 TDH -0.58 -5.38 -0.43 3.64e-7 Triglycerides; TGCT cis rs4919687 0.679 rs12762176 chr10:104499232 A/T cg05855489 chr10:104503620 C10orf26 0.57 4.55 0.38 1.27e-5 Colorectal cancer; TGCT cis rs7666738 0.830 rs35915560 chr4:98978649 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.06 0.41 1.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs72781680 0.752 rs72796119 chr2:23917179 C/T cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.597 rs2485631 chr6:146190077 G/C cg23711669 chr6:146136114 FBXO30 0.76 7.14 0.54 6.99e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg14416726 chr6:151773293 C6orf211;RMND1 -1.05 -14.4 -0.79 3.16e-28 Menarche (age at onset); TGCT cis rs7647973 0.769 rs11130181 chr3:49109919 G/A cg07636037 chr3:49044803 WDR6 0.79 6.56 0.51 1.32e-9 Menarche (age at onset); TGCT cis rs62392365 0.686 rs115989354 chr6:25208585 C/T cg16898833 chr6:26189333 HIST1H4D 0.95 4.59 0.38 1.06e-5 Schizophrenia;Intelligence (multi-trait analysis); TGCT cis rs9916302 0.784 rs4795361 chr17:37573446 G/A cg15445000 chr17:37608096 MED1 0.34 4.8 0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs716804 0.608 rs7944706 chr11:10331311 A/G cg17061862 chr11:9590431 NA -0.37 -4.55 -0.38 1.27e-5 Neuroticism; TGCT cis rs4595586 0.505 rs11611321 chr12:39390803 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs4242434 0.889 rs7817772 chr8:22539316 A/G cg03733263 chr8:22462867 KIAA1967 -1.13 -15.54 -0.81 6.82e-31 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs5758659 0.657 rs5758587 chr22:42517636 C/G cg15557168 chr22:42548783 NA 0.18 4.63 0.38 9.14e-6 Cognitive function; TGCT cis rs10892173 0.765 rs7125693 chr11:117670651 C/T cg07621104 chr11:117668040 DSCAML1 0.5 5.29 0.43 5.36e-7 Myopia; TGCT cis rs2836974 0.583 rs2735307 chr21:40713358 C/T cg11890956 chr21:40555474 PSMG1 0.77 7.68 0.57 4.22e-12 Cognitive function; TGCT cis rs9560113 1.000 rs9560109 chr13:112180468 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs9527 0.590 rs11191572 chr10:104893137 A/G cg04362960 chr10:104952993 NT5C2 0.69 5.82 0.46 4.78e-8 Arsenic metabolism; TGCT cis rs9322193 0.923 rs10782316 chr6:150073891 A/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs1577917 0.665 rs4304137 chr6:86217448 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.59 5.15 0.42 1.01e-6 Response to antipsychotic treatment; TGCT cis rs10504229 0.683 rs11786074 chr8:58133532 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9467711 0.606 rs72836482 chr6:26359241 A/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2439831 0.557 rs13329084 chr15:44151063 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.68 -4.44 -0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs76419734 0.510 rs961472 chr4:106535062 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.78 4.74 0.39 5.87e-6 Post bronchodilator FEV1; TGCT cis rs13191362 0.935 rs34934114 chr6:163082480 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.36 0.6 1.07e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs114540395 0.858 rs17767748 chr10:103285900 A/G cg10198749 chr1:39920707 MACF1 -0.6 -7.64 -0.57 5.03e-12 Schizophrenia; TGCT cis rs6582630 0.615 rs12821226 chr12:38546406 C/T cg26384229 chr12:38710491 ALG10B -0.53 -4.77 -0.39 5.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs8180040 0.903 rs13094438 chr3:47277885 G/A cg27129171 chr3:47204927 SETD2 0.69 8.59 0.61 3.04e-14 Colorectal cancer; TGCT cis rs6684514 0.961 rs12126696 chr1:156241348 C/T cg16558208 chr1:156270281 VHLL 0.48 9.46 0.65 2.55e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs11731606 0.567 rs17377951 chr4:95321099 C/T cg00507259 chr4:95128692 SMARCAD1 0.7 5.09 0.42 1.3e-6 Mean platelet volume; TGCT cis rs6463523 0.898 rs66892628 chr7:759374 T/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.87 11.91 0.73 2.85e-22 Subjective well-being; TGCT cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg20637647 chr7:64974828 NA 0.96 5.59 0.45 1.41e-7 Diabetic kidney disease; TGCT cis rs6089829 0.962 rs6122352 chr20:61668284 T/C cg08564027 chr20:61660810 NA 0.37 6.88 0.53 2.69e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1008375 0.932 rs12500912 chr4:17603318 C/T cg18681998 chr4:17616180 MED28 0.99 9.69 0.66 7.08e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9682041 0.808 rs9875109 chr3:170064776 A/G cg11886554 chr3:170076028 SKIL -0.57 -4.74 -0.39 5.65e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs12049351 0.719 rs10916493 chr1:229634397 G/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs3820928 0.874 rs13403281 chr2:227880769 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -4.94 -0.41 2.51e-6 Pulmonary function; TGCT cis rs4319547 0.695 rs1803290 chr12:122865029 T/C cg08088222 chr12:122070432 ORAI1 -0.25 -4.49 -0.37 1.58e-5 Body mass index; TGCT cis rs259282 0.538 rs8100917 chr19:33114702 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.5 4.56 0.38 1.2e-5 Schizophrenia; TGCT cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs7264396 0.790 rs2425125 chr20:34330954 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.29 5.25 0.43 6.33e-7 Total cholesterol levels; TGCT cis rs17221829 0.899 rs10830356 chr11:89443939 C/A cg02982614 chr11:89391479 FOLH1B -0.29 -5.08 -0.41 1.36e-6 Anxiety in major depressive disorder; TGCT cis rs907683 0.584 rs1058284 chr2:220286142 G/A cg15015639 chr2:220282977 DES -0.39 -4.83 -0.4 3.88e-6 Resting heart rate; TGCT cis rs3752962 0.630 rs11078793 chr17:1951364 T/A cg24156229 chr17:1948635 NA -0.38 -7.4 -0.55 1.8e-11 Itch intensity from mosquito bite; TGCT cis rs611744 0.550 rs57045491 chr8:109279120 A/C cg21045802 chr8:109455806 TTC35 0.72 7.43 0.56 1.53e-11 Dupuytren's disease; TGCT cis rs9372498 0.732 rs17080124 chr6:118717814 A/G cg21191810 chr6:118973309 C6orf204 -0.45 -4.76 -0.39 5.38e-6 Diastolic blood pressure; TGCT cis rs7666738 0.887 rs34509663 chr4:98982531 C/T cg18180107 chr4:99064573 C4orf37 0.56 4.54 0.38 1.3e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.931 rs9840050 chr3:49133310 A/G cg05785598 chr3:49045655 WDR6 0.36 4.77 0.39 5.17e-6 Parkinson's disease; TGCT cis rs8177253 0.965 rs3811658 chr3:133476852 C/T cg08439880 chr3:133502540 NA -0.3 -5.52 -0.44 1.88e-7 Iron status biomarkers; TGCT cis rs797680 0.964 rs2152358 chr1:93634009 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.27 -0.43 5.78e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7000551 0.689 rs6997299 chr8:22324268 T/C cg12081754 chr8:22256438 SLC39A14 0.28 4.52 0.38 1.45e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs13064411 0.597 rs2291905 chr3:113010466 C/T cg18753928 chr3:113234510 CCDC52 -0.52 -4.61 -0.38 9.96e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs11085466 0.615 rs76695906 chr19:21766710 G/A cg23026602 chr19:21646605 NA -0.57 -4.59 -0.38 1.05e-5 Colorectal or endometrial cancer; TGCT cis rs5769765 1.000 rs4824112 chr22:50284345 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.18 -13.1 -0.76 3.8e-25 Schizophrenia; TGCT cis rs11748684 1.000 rs72754922 chr5:42547714 G/A cg01169772 chr5:41904236 C5orf51 -0.9 -4.5 -0.37 1.57e-5 Response to taxane treatment (docetaxel); TGCT cis rs7100689 0.784 rs11202699 chr10:82131453 A/G cg01528321 chr10:82214614 TSPAN14 0.88 8.48 0.61 5.61e-14 Post bronchodilator FEV1; TGCT cis rs3806843 0.520 rs265312 chr5:140296272 T/G cg07102913 chr5:140593443 PCDHB13 -0.49 -4.73 -0.39 5.98e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg03452623 chr4:187889614 NA -0.36 -5.66 -0.45 9.75e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs72781680 0.678 rs2551341 chr2:24014778 G/T cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs8013055 0.846 rs35723046 chr14:105970548 C/T cg23356831 chr14:105996513 TMEM121 0.41 6.24 0.49 6.39e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9534288 0.699 rs2146884 chr13:46660392 T/C cg15192986 chr13:46630673 CPB2 -0.53 -6.41 -0.5 2.75e-9 Blood protein levels; TGCT cis rs796364 1.000 rs281771 chr2:200812202 A/C cg17644776 chr2:200775616 C2orf69 -0.31 -4.89 -0.4 3.12e-6 Schizophrenia; TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg11494091 chr17:61959527 GH2 0.61 14.18 0.79 1.01e-27 Prudent dietary pattern; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg06753367 chr22:24256600 NA -0.24 -4.56 -0.38 1.22e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2456568 0.741 rs10831137 chr11:93636912 C/T cg17595323 chr11:93583763 C11orf90 -0.47 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg17971929 chr21:40555470 PSMG1 -0.67 -6.27 -0.49 5.46e-9 Cognitive function; TGCT trans rs57221529 0.766 rs12519763 chr5:559145 C/T cg25482853 chr8:67687455 SGK3 1.2 10.16 0.67 5.25e-18 Lung disease severity in cystic fibrosis; TGCT cis rs1894292 0.527 rs4235119 chr4:74372801 C/G cg05868023 chr4:75230803 EREG -0.55 -5.01 -0.41 1.85e-6 Prostate cancer; TGCT cis rs12200560 0.505 rs172425 chr6:97075299 A/T cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs12765878 1.000 rs2067832 chr10:105643134 G/A cg11005552 chr10:105648138 OBFC1 0.44 7.6 0.56 6.24e-12 Coronary artery disease; TGCT cis rs587847 0.737 rs17540662 chr15:37665328 C/T cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.65 0.45 1.06e-7 Alzheimer's disease; TGCT cis rs593982 0.925 rs585272 chr11:65505289 A/G cg08755490 chr11:65554678 OVOL1 1.36 11.08 0.71 2.98e-20 Atopic dermatitis; TGCT cis rs10504229 0.683 rs882429 chr8:58129292 A/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs10193935 0.901 rs222469 chr2:42640235 T/C cg27598129 chr2:42591480 NA -0.39 -5.52 -0.44 1.93e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1215050 0.791 rs7688942 chr4:98832048 T/C cg05340658 chr4:99064831 C4orf37 0.47 5.9 0.47 3.2e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs3806843 0.547 rs246065 chr5:140323638 A/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9388451 0.874 rs3734634 chr6:126111800 G/A cg05901451 chr6:126070800 HEY2 -1.0 -14.26 -0.79 6.67e-28 Brugada syndrome; TGCT cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg17554472 chr22:41940697 POLR3H 0.43 4.6 0.38 1.01e-5 Vitiligo; TGCT cis rs1784581 0.651 rs3016568 chr6:162388158 G/A cg17173639 chr6:162384350 PARK2 -0.47 -8.16 -0.59 3.15e-13 Itch intensity from mosquito bite; TGCT cis rs7772486 0.790 rs6570723 chr6:146151230 A/T cg23711669 chr6:146136114 FBXO30 0.89 10.12 0.67 6.38e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2230307 0.572 rs512999 chr1:100563330 A/G cg24955406 chr1:100503596 HIAT1 0.75 5.13 0.42 1.1e-6 Carotid intima media thickness; TGCT cis rs2486012 1.000 rs3011230 chr1:44340655 A/C cg12908607 chr1:44402522 ARTN 0.72 5.68 0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.966 rs4235392 chr4:17696422 A/G cg18681998 chr4:17616180 MED28 0.78 7.29 0.55 3.14e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9814567 0.896 rs6794258 chr3:134344505 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.8 -7.29 -0.55 3.14e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7119038 0.730 rs10790269 chr11:118729456 C/T cg19308663 chr11:118741387 NA -0.32 -5.88 -0.47 3.6e-8 Sjögren's syndrome; TGCT cis rs28595532 0.764 rs55913633 chr4:119747444 C/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs4862750 0.914 rs7658351 chr4:187875680 G/T cg11301795 chr4:187892539 NA -0.35 -5.28 -0.43 5.58e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg24503407 chr1:205819492 PM20D1 0.67 10.78 0.7 1.61e-19 Menarche (age at onset); TGCT cis rs1577917 0.958 rs12195776 chr6:86488599 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.69 -5.63 -0.45 1.16e-7 Response to antipsychotic treatment; TGCT cis rs3087591 0.659 rs2214538 chr17:29636570 C/T cg24425628 chr17:29625626 OMG;NF1 0.41 6.01 0.47 1.93e-8 Hip circumference; TGCT cis rs9300255 0.596 rs11057207 chr12:123730891 T/G cg00376283 chr12:123451042 ABCB9 0.79 6.72 0.52 6e-10 Neutrophil percentage of white cells; TGCT cis rs9329221 0.905 rs6601451 chr8:10243681 C/G cg27411982 chr8:10470053 RP1L1 -0.23 -4.9 -0.4 2.95e-6 Neuroticism; TGCT cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg11279151 chr3:101281821 RG9MTD1 0.43 9.38 0.64 4.06e-16 Colonoscopy-negative controls vs population controls; TGCT trans rs4650994 0.935 rs2811289 chr1:178572693 G/A cg05059571 chr16:84539110 KIAA1609 0.39 7.01 0.53 1.33e-10 HDL cholesterol levels;HDL cholesterol; TGCT cis rs11718455 0.960 rs3843373 chr3:44011053 C/T cg08738300 chr3:44038990 NA -0.86 -6.55 -0.51 1.4e-9 Coronary artery disease; TGCT cis rs12971120 0.685 rs34780792 chr18:72173278 G/A cg25817165 chr18:72167213 CNDP2 -0.28 -4.84 -0.4 3.71e-6 Refractive error; TGCT cis rs8017423 0.967 rs61996919 chr14:90701803 A/C cg04374321 chr14:90722782 PSMC1 0.77 8.04 0.59 6.19e-13 Mortality in heart failure; TGCT cis rs68170813 0.641 rs77487103 chr7:107078793 T/C cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs478304 0.651 rs4014195 chr11:65506822 C/G cg10518572 chr11:65560635 OVOL1 0.23 4.49 0.37 1.62e-5 Acne (severe); TGCT cis rs8062405 0.964 rs72793809 chr16:28832382 C/T cg09754948 chr16:28834200 ATXN2L 0.61 4.54 0.38 1.34e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs8177253 0.965 rs3811658 chr3:133476852 C/T cg11941060 chr3:133502564 NA -0.29 -5.93 -0.47 2.84e-8 Iron status biomarkers; TGCT cis rs9814567 1.000 rs3932818 chr3:134206069 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -9.27 -0.64 7.51e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs17221829 0.627 rs10830315 chr11:89375574 G/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs72781680 0.898 rs72780118 chr2:23994431 G/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg00786635 chr1:25594202 NA 0.6 6.25 0.49 6.15e-9 Erythrocyte sedimentation rate; TGCT cis rs12711979 0.740 rs6711964 chr2:3820916 A/T cg17052675 chr2:3827356 NA -0.4 -7.82 -0.57 2.02e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs2013441 1.000 rs11871827 chr17:20215905 C/G cg18979559 chr17:20280153 CCDC144C -0.43 -4.56 -0.38 1.21e-5 Obesity-related traits; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs9527 0.590 rs7898770 chr10:104756636 A/G cg15744005 chr10:104629667 AS3MT 0.45 5.29 0.43 5.38e-7 Arsenic metabolism; TGCT cis rs9309473 0.579 rs6728128 chr2:73595982 T/C cg20560298 chr2:73613845 ALMS1 -0.41 -4.54 -0.38 1.31e-5 Metabolite levels; TGCT cis rs68170813 0.559 rs76859341 chr7:107070146 C/G cg02696742 chr7:106810147 HBP1 -0.71 -5.77 -0.46 5.86e-8 Coronary artery disease; TGCT cis rs11105298 0.891 rs11105314 chr12:89924559 C/T cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2153535 0.580 rs1577467 chr6:8444241 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs10832963 0.847 rs4237722 chr11:18639363 T/C cg09201001 chr11:18656081 SPTY2D1 1.01 10.56 0.69 5.45e-19 Breast cancer; TGCT cis rs273218 0.573 rs10513033 chr5:53333477 T/C ch.5.1024479R chr5:53302184 ARL15 -0.58 -4.79 -0.4 4.61e-6 Migraine; TGCT cis rs62380364 0.727 rs188582 chr5:88167740 G/C cg22951263 chr5:87985283 NA 0.5 5.02 0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.825 rs6588441 chr1:53223494 G/A cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.29e-11 Monocyte count; TGCT cis rs9814567 1.000 rs9985341 chr3:134232840 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.74 -5.61 -0.45 1.24e-7 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4253772 0.678 rs1055659 chr22:46638298 C/T cg09491104 chr22:46646882 C22orf40 -0.48 -4.81 -0.4 4.37e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs17681684 0.565 rs12150167 chr17:9764244 C/A cg15743799 chr17:9805578 RCVRN -0.27 -5.89 -0.47 3.45e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs9300255 0.602 rs1727306 chr12:123665695 A/G cg00376283 chr12:123451042 ABCB9 0.73 5.69 0.46 8.5e-8 Neutrophil percentage of white cells; TGCT cis rs7659604 0.702 rs6815790 chr4:122695385 A/C cg19748678 chr4:122722346 EXOSC9 0.83 8.81 0.62 9.19e-15 Type 2 diabetes; TGCT trans rs4332037 0.539 rs56016347 chr7:2060126 C/T cg10840412 chr1:235813424 GNG4 0.94 6.84 0.52 3.21e-10 Bipolar disorder; TGCT cis rs2862064 0.613 rs2862060 chr5:156443895 A/C cg12943317 chr5:156479607 HAVCR1 -0.38 -5.2 -0.42 8.06e-7 Platelet count; TGCT cis rs12479064 0.724 rs11885942 chr2:100004165 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.57 -4.47 -0.37 1.71e-5 Chronic sinus infection; TGCT cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs832540 0.931 rs832536 chr5:56212595 C/T cg24531977 chr5:56204891 C5orf35 -0.52 -5.18 -0.42 8.65e-7 Coronary artery disease; TGCT cis rs7312933 0.618 rs7954523 chr12:42681508 A/G cg19980929 chr12:42632907 YAF2 0.41 5.61 0.45 1.26e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7572733 0.555 rs11903129 chr2:198918591 A/T cg00792783 chr2:198669748 PLCL1 0.59 5.15 0.42 1.01e-6 Dermatomyositis; TGCT cis rs7666738 0.546 rs1863602 chr4:98909304 T/C cg05340658 chr4:99064831 C4orf37 0.59 6.4 0.5 2.86e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7937682 0.889 rs1784786 chr11:111486043 A/G cg09085632 chr11:111637200 PPP2R1B 1.15 10.17 0.67 4.84e-18 Primary sclerosing cholangitis; TGCT cis rs9549367 0.789 rs7999579 chr13:113879357 T/C cg18105134 chr13:113819100 PROZ -0.33 -5.38 -0.43 3.61e-7 Platelet distribution width; TGCT cis rs9311474 0.581 rs13621 chr3:52558133 T/C cg10802521 chr3:52805072 NEK4 -0.73 -8.95 -0.63 4.39e-15 Electroencephalogram traits; TGCT cis rs174601 0.861 rs174581 chr11:61606683 G/A cg01500311 chr11:61656094 FADS3 -0.33 -5.8 -0.46 5.23e-8 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs79387448 0.745 rs7572284 chr2:103119423 C/A cg09003973 chr2:102972529 NA 0.86 5.72 0.46 7.67e-8 Gut microbiota (bacterial taxa); TGCT cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.32 -0.6 1.35e-13 Platelet count; TGCT cis rs933688 0.877 rs10474352 chr5:90732225 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.03 8.68 0.61 1.89e-14 Smoking behavior; TGCT cis rs17826219 0.636 rs7221463 chr17:29080551 A/C cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.38e-6 Body mass index; TGCT cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs11250097 0.549 rs11778177 chr8:11310362 C/T cg01383082 chr8:11323474 FAM167A 0.28 4.54 0.38 1.3e-5 Neuroticism; TGCT cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs617219 0.551 rs2131978 chr5:78613986 G/A cg05890484 chr5:78407552 BHMT -0.34 -4.62 -0.38 9.35e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs11098499 0.754 rs1546503 chr4:120241167 T/C cg09307838 chr4:120376055 NA 0.61 5.89 0.47 3.33e-8 Corneal astigmatism; TGCT cis rs7267979 1.000 rs2297496 chr20:25295787 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6860806 0.507 rs272872 chr5:131675864 C/T cg16647868 chr5:131706066 SLC22A5 -0.3 -4.47 -0.37 1.77e-5 Breast cancer; TGCT cis rs7552404 0.824 rs1251079 chr1:76189445 C/T cg22875332 chr1:76189707 ACADM 0.83 12.87 0.76 1.38e-24 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4663866 0.803 rs71426511 chr2:239180200 G/A cg17283117 chr2:239148619 HES6 0.99 4.57 0.38 1.15e-5 Irritable bowel syndrome; TGCT trans rs4819388 0.789 rs4568033 chr21:45649778 A/G cg17383793 chr5:52405638 MOCS2 0.69 6.94 0.53 1.92e-10 Celiac disease; TGCT cis rs6089584 0.566 rs2146852 chr20:60616492 T/G cg06108461 chr20:60628389 TAF4 -0.44 -5.58 -0.45 1.44e-7 Body mass index; TGCT cis rs6598955 0.671 rs11247900 chr1:26612460 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs7312933 0.618 rs7315968 chr12:42637086 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.16 0.42 9.61e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT trans rs7618501 0.603 rs72942333 chr3:49986118 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.9 10.11 0.67 6.82e-18 Intelligence (multi-trait analysis); TGCT trans rs9383153 1.000 rs2237223 chr6:16329741 G/A cg19402885 chr12:15475236 PTPRO 0.99 6.81 0.52 3.76e-10 Gambling; TGCT cis rs35306767 0.855 rs11253499 chr10:944090 A/C cg26597838 chr10:835615 NA 0.76 10.69 0.69 2.61e-19 Eosinophil percentage of granulocytes; TGCT cis rs4805272 0.539 rs1075733 chr19:29324460 C/T cg03161606 chr19:29218774 NA 0.54 4.48 0.37 1.68e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs4819052 0.819 rs7279136 chr21:46692287 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg03395511 chr6:291903 DUSP22 -0.7 -7.2 -0.54 4.99e-11 Menopause (age at onset); TGCT cis rs1472147 0.503 rs62479604 chr7:128433964 T/C cg00260937 chr7:128520193 KCP 0.43 4.89 0.4 3.09e-6 Calcium levels; TGCT cis rs7635838 0.619 rs346087 chr3:11274354 A/G cg00170343 chr3:11313890 ATG7 0.65 6.1 0.48 1.25e-8 HDL cholesterol; TGCT cis rs6088590 0.648 rs6059991 chr20:33280836 C/T cg06115741 chr20:33292138 TP53INP2 0.57 4.86 0.4 3.51e-6 Coronary artery disease; TGCT cis rs1775715 0.769 rs2808102 chr10:32117749 A/T cg14930904 chr10:32216787 ARHGAP12 0.5 4.85 0.4 3.62e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs775227 0.574 rs79709668 chr3:113161265 G/A cg18753928 chr3:113234510 CCDC52 -0.66 -4.53 -0.38 1.39e-5 Dental caries; TGCT cis rs2288073 0.965 rs10185445 chr2:24410976 A/C cg05570707 chr2:24270316 C2orf44 0.5 4.49 0.37 1.58e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs9858542 0.537 rs115753735 chr3:49355005 T/C cg00383909 chr3:49044727 WDR6 0.7 4.85 0.4 3.64e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs59197085 0.636 rs3807133 chr7:128469760 G/A cg00260937 chr7:128520193 KCP 0.47 4.89 0.4 3.03e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs77372450 0.551 rs7728747 chr5:157083635 C/T cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.48e-6 Bipolar disorder (body mass index interaction); TGCT cis rs10174077 0.874 rs10186656 chr2:152475938 T/G cg19508488 chr2:152266495 RIF1 0.7 6.53 0.51 1.54e-9 Squamous cell lung carcinoma; TGCT cis rs6121246 0.567 rs6060261 chr20:30192948 C/G cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs7824557 0.602 rs7819395 chr8:11211068 T/C cg21775007 chr8:11205619 TDH 0.73 7.03 0.53 1.23e-10 Retinal vascular caliber; TGCT cis rs2468186 0.583 rs2450067 chr8:120096533 C/T cg02248809 chr8:120845432 TAF2 -0.45 -4.83 -0.4 3.99e-6 Osteoprotegerin levels; TGCT cis rs9611565 0.568 rs5758441 chr22:42132888 C/A cg06634786 chr22:41940651 POLR3H 0.79 7.29 0.55 3.13e-11 Vitiligo; TGCT cis rs35160687 0.862 rs13023154 chr2:86516984 A/G cg03171300 chr2:86307199 POLR1A -0.27 -5.03 -0.41 1.69e-6 Night sleep phenotypes; TGCT cis rs1577917 0.739 rs9450318 chr6:86427177 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.59 5.07 0.41 1.42e-6 Response to antipsychotic treatment; TGCT cis rs244731 1.000 rs244729 chr5:176539018 C/G cg16006841 chr5:176797999 RGS14 0.51 6.47 0.5 2.01e-9 Urate levels in lean individuals; TGCT cis rs3821902 0.646 rs10510901 chr3:64013062 A/G cg22134162 chr3:63841271 THOC7 -0.31 -4.85 -0.4 3.58e-6 Breast cancer; TGCT trans rs2688608 0.839 rs2633310 chr10:75594050 G/T cg13918328 chr10:52500089 ASAH2B -0.69 -6.73 -0.52 5.47e-10 Inflammatory bowel disease; TGCT cis rs12134133 0.962 rs7526658 chr1:207413443 A/G cg02152968 chr1:207494213 CD55 0.6 4.65 0.39 8.43e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs1008375 0.866 rs12233712 chr4:17570063 T/A cg18681998 chr4:17616180 MED28 0.88 8.97 0.63 3.94e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.512 rs165251 chr4:98758490 C/G cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs589249 0.963 rs11263940 chr1:37182486 C/T cg04012535 chr1:37176647 NA 0.32 5.18 0.42 8.63e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs73058052 1.000 rs12462756 chr19:50098423 G/A cg09250473 chr19:50168907 IRF3;BCL2L12 0.87 6.6 0.51 1.06e-9 Fibrinogen levels; TGCT cis rs916888 0.773 rs199533 chr17:44828931 G/A cg17911788 chr17:44343683 NA -0.68 -7.21 -0.54 4.72e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10510102 0.872 rs10887032 chr10:123715402 C/T cg23691251 chr10:123688108 ATE1 0.55 4.5 0.37 1.55e-5 Breast cancer; TGCT cis rs9372498 0.536 rs72954806 chr6:118899965 C/G cg07617317 chr6:118971624 C6orf204 0.49 5.19 0.42 8.37e-7 Diastolic blood pressure; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg22166914 chr1:53195759 ZYG11B -0.35 -5.75 -0.46 6.65e-8 Monocyte count; TGCT cis rs2235642 1.000 rs2235642 chr16:1584866 T/C cg08296037 chr16:1584118 IFT140;TMEM204 -0.3 -5.51 -0.44 2.01e-7 Coronary artery disease; TGCT cis rs3780378 0.875 rs10115312 chr9:5003973 G/T cg02405213 chr9:5042618 JAK2 -0.6 -7.79 -0.57 2.26e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs950169 0.922 rs11630760 chr15:85113337 G/T cg12863693 chr15:85201151 NMB 0.39 4.44 0.37 1.99e-5 Schizophrenia; TGCT cis rs61935443 0.720 rs892493 chr12:95283943 T/C cg21533806 chr12:95267307 NA 0.52 4.49 0.37 1.61e-5 Schizophrenia; TGCT cis rs7017914 0.967 rs13256250 chr8:71596193 G/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs2456568 0.709 rs12806128 chr11:93634972 C/T cg26875233 chr11:93583750 C11orf90 0.47 6.04 0.48 1.65e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs17253792 0.822 rs77197405 chr14:56159662 T/A cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs7635838 0.892 rs34830847 chr3:11437798 A/C cg00170343 chr3:11313890 ATG7 0.65 6.23 0.49 6.56e-9 HDL cholesterol; TGCT cis rs4819052 0.851 rs2838866 chr21:46713014 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 4.57 0.38 1.17e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7178572 0.568 rs12901739 chr15:77395491 C/T cg15453836 chr15:77711506 NA -0.4 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs7582180 0.764 rs1967341 chr2:100924559 T/C cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs739496 0.615 rs617044 chr12:112132875 T/C cg10833066 chr12:111807467 FAM109A 0.37 4.79 0.39 4.76e-6 Platelet count; TGCT cis rs7647973 1.000 rs9842132 chr3:49427933 G/A cg05785598 chr3:49045655 WDR6 -0.4 -4.67 -0.39 7.57e-6 Menarche (age at onset); TGCT cis rs35306767 0.855 rs11253459 chr10:886402 C/T cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs765787 0.530 rs28526629 chr15:45540462 C/T cg24006582 chr15:45444508 DUOX1 -0.24 -5.29 -0.43 5.34e-7 Uric acid levels; TGCT cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg23708337 chr7:1209742 NA 0.56 5.09 0.42 1.31e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10751667 0.666 rs4074235 chr11:977511 C/G cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs11887277 0.676 rs9646996 chr2:27044097 A/G cg14949065 chr2:27373128 TCF23 0.19 4.46 0.37 1.8e-5 Obesity-related traits; TGCT cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs17376456 1.000 rs13185608 chr5:93509688 T/G cg25358565 chr5:93447407 FAM172A 0.95 7.97 0.58 8.71e-13 Diabetic retinopathy; TGCT cis rs9902453 0.967 rs4429345 chr17:28458105 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -6.39 -0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs2239908 0.718 rs241776 chr17:26644308 C/T cg10342447 chr17:26645325 TMEM97 0.62 6.26 0.49 5.78e-9 Blood protein levels; TGCT cis rs1580019 0.562 rs4720064 chr7:32559638 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.56 4.8 0.4 4.53e-6 Cognitive ability; TGCT cis rs9611565 0.503 rs5996062 chr22:42167464 C/G cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs12220238 1.000 rs12252705 chr10:75984863 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7528684 0.752 rs6427402 chr1:157749544 C/T cg17134153 chr1:157670328 FCRL3 -0.28 -5.13 -0.42 1.08e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs4900538 0.963 rs942023 chr14:102972170 T/C cg18135206 chr14:102964638 TECPR2 0.21 5.0 0.41 1.95e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs10088262 0.629 rs7827665 chr8:124804190 G/A cg02993010 chr8:124780839 FAM91A1 -0.63 -5.13 -0.42 1.08e-6 Pancreatic cancer; TGCT cis rs3806843 0.608 rs246042 chr5:140330967 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT trans rs797680 0.789 rs7539307 chr1:93652703 G/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.81 -0.52 3.79e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs910316 0.763 rs1548807 chr14:75479582 T/G cg11812906 chr14:75593930 NEK9 0.58 5.56 0.45 1.6e-7 Height; TGCT cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg13393036 chr8:95962371 TP53INP1 -0.65 -8.88 -0.62 6.27e-15 Type 2 diabetes; TGCT cis rs137699 1.000 rs760742 chr22:39755190 G/T cg11247378 chr22:39784982 NA -0.46 -5.09 -0.42 1.28e-6 IgG glycosylation; TGCT cis rs7208859 0.673 rs1347360 chr17:28914532 T/C cg04154034 chr17:28927549 LRRC37B2 0.85 5.03 0.41 1.68e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12477438 0.798 rs10196680 chr2:99628617 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg09904177 chr6:26538194 HMGN4 0.64 5.78 0.46 5.73e-8 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.673 rs6449156 chr4:9956712 G/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.12e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.830 rs28619044 chr4:98789814 G/C cg18180107 chr4:99064573 C4orf37 0.53 5.05 0.41 1.51e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6669919 0.540 rs11579048 chr1:211681919 C/G cg10512769 chr1:211675356 NA -0.25 -4.49 -0.37 1.61e-5 Intelligence (multi-trait analysis); TGCT cis rs4975616 0.869 rs421284 chr5:1325590 T/C cg07493874 chr5:1342172 CLPTM1L -0.29 -6.99 -0.53 1.49e-10 Lung cancer; TGCT cis rs9383153 0.590 rs2072736 chr6:16328068 T/C cg14009473 chr6:15502099 JARID2 0.67 5.16 0.42 9.52e-7 Gambling; TGCT cis rs1245541 0.720 rs1668157 chr10:73906150 A/G cg09661010 chr10:73848153 SPOCK2 -0.37 -4.53 -0.38 1.39e-5 Insulin-like growth factors; TGCT cis rs782590 0.934 rs62165184 chr2:55788253 G/C cg03859395 chr2:55845619 SMEK2 0.93 11.51 0.72 2.61e-21 Metabolic syndrome; TGCT cis rs7666738 0.830 rs7663661 chr4:99014761 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs67478160 0.619 rs28698555 chr14:104316486 C/A cg26031613 chr14:104095156 KLC1 0.68 6.98 0.53 1.59e-10 Schizophrenia; TGCT cis rs1577917 0.958 rs10455448 chr6:86533611 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs727563 0.594 rs5758408 chr22:42077737 A/C cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs72781680 0.800 rs6718635 chr2:24066183 A/C cg08917208 chr2:24149416 ATAD2B 0.9 5.6 0.45 1.29e-7 Lymphocyte counts; TGCT cis rs921968 0.643 rs711186 chr2:219346102 A/G cg02176678 chr2:219576539 TTLL4 -0.43 -6.44 -0.5 2.37e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs782590 0.818 rs2627782 chr2:55825352 A/G cg18811423 chr2:55921094 PNPT1 0.55 5.72 0.46 7.65e-8 Metabolic syndrome; TGCT cis rs2735413 0.599 rs73562710 chr16:78124606 T/C cg09132178 chr16:78079569 NA 0.35 4.49 0.37 1.63e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs6912958 0.525 rs59322 chr6:88020521 C/A cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.94 0.47 2.69e-8 Monocyte percentage of white cells; TGCT cis rs4253772 0.530 rs6008623 chr22:46710024 G/A cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg03395511 chr6:291903 DUSP22 -0.71 -7.28 -0.55 3.36e-11 Menopause (age at onset); TGCT cis rs7432375 0.933 rs6791142 chr3:136377377 C/T cg12473912 chr3:136751656 NA 0.36 5.06 0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs796364 0.806 rs74771155 chr2:200913743 C/T cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs35771425 0.642 rs3767380 chr1:211452845 A/G cg26515805 chr1:211431828 RCOR3 -0.44 -4.65 -0.39 8.52e-6 Educational attainment (years of education); TGCT cis rs7178424 0.742 rs12916268 chr15:62175642 G/A cg00456672 chr15:62358751 C2CD4A -0.31 -4.73 -0.39 6e-6 Height; TGCT cis rs3008870 1.000 rs3008856 chr1:67387901 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs524281 0.861 rs4013917 chr11:65926185 A/G cg00563793 chr11:65837595 PACS1 0.58 4.92 0.4 2.66e-6 Electroencephalogram traits; TGCT cis rs2549003 0.870 rs61175929 chr5:131821548 C/G cg00255919 chr5:131827918 IRF1 0.2 4.64 0.38 8.73e-6 Asthma (sex interaction); TGCT cis rs4253772 0.591 rs6007727 chr22:46650959 G/A cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs28595532 0.668 rs58467651 chr4:119349011 T/G cg14228332 chr4:119757509 SEC24D 0.74 4.53 0.38 1.39e-5 Cannabis dependence symptom count; TGCT cis rs9677476 0.608 rs6437005 chr2:232055735 A/G cg27665808 chr2:232055229 NA 0.35 4.5 0.37 1.52e-5 Food antigen IgG levels; TGCT cis rs10823500 0.777 rs2184335 chr10:72006891 C/T cg04118878 chr10:71993077 PPA1 0.57 5.11 0.42 1.16e-6 Blood protein levels; TGCT cis rs7267979 0.744 rs6050464 chr20:25209299 C/A cg16686733 chr20:25566563 NINL 0.53 4.95 0.41 2.37e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13242816 1.000 rs56063232 chr7:116172808 G/T cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs9926296 1.000 rs9926296 chr16:89818089 A/G cg26513180 chr16:89883248 FANCA 0.89 10.24 0.68 3.28e-18 Vitiligo; TGCT cis rs6088590 1.000 rs6088595 chr20:33358499 T/A cg06115741 chr20:33292138 TP53INP2 0.64 5.34 0.43 4.29e-7 Coronary artery disease; TGCT cis rs80282103 0.618 rs17155886 chr10:1145182 A/G cg08668510 chr10:1095578 IDI1 1.05 5.31 0.43 4.8e-7 Glomerular filtration rate (creatinine); TGCT cis rs875971 0.617 rs810400 chr7:66022889 G/C cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs4938534 0.716 rs7947229 chr11:111289354 T/G cg24049888 chr11:111250129 POU2AF1 -0.25 -4.44 -0.37 1.98e-5 Primary biliary cholangitis; TGCT cis rs6582630 0.519 rs7305545 chr12:38349223 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.33e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1150668 0.799 rs1150705 chr6:28193786 T/G cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.61 -0.38 9.84e-6 Pubertal anthropometrics; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg27535305 chr1:53392650 SCP2 -0.26 -5.07 -0.41 1.43e-6 Monocyte count; TGCT cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs116095464 0.558 rs62344300 chr5:246336 A/G cg22857025 chr5:266934 NA -0.34 -6.67 -0.51 7.72e-10 Breast cancer; TGCT cis rs3820928 0.874 rs10202239 chr2:227901819 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs2072499 0.750 rs909269 chr1:156192028 C/T cg25208724 chr1:156163844 SLC25A44 0.94 8.7 0.62 1.73e-14 Testicular germ cell tumor; TGCT cis rs10464366 0.746 rs17171537 chr7:39145647 C/T cg15212455 chr7:39170539 POU6F2 0.26 5.9 0.47 3.21e-8 IgG glycosylation; TGCT cis rs832540 0.656 rs832573 chr5:56159578 T/C cg12311346 chr5:56204834 C5orf35 -0.48 -4.91 -0.4 2.78e-6 Coronary artery disease; TGCT cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs763014 0.966 rs4144003 chr16:645968 C/T cg00908189 chr16:619842 PIGQ 0.85 10.14 0.67 5.88e-18 Height; TGCT cis rs7666738 0.606 rs6852813 chr4:99084671 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.89 7.32 0.55 2.74e-11 Platelet count; TGCT cis rs12530845 0.832 rs56306315 chr7:135329107 C/T cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs56011263 0.687 rs4690187 chr4:703813 C/T cg20735989 chr4:730612 PCGF3 -0.24 -5.43 -0.44 2.86e-7 White blood cell count; TGCT cis rs2439831 0.867 rs2251844 chr15:43836478 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.79 0.46 5.33e-8 Lung cancer in ever smokers; TGCT cis rs9302001 0.960 rs9302000 chr13:95460995 C/G cg07483244 chr13:95358924 NA 0.37 4.81 0.4 4.22e-6 Panic disorder; TGCT cis rs6586111 1.000 rs6586109 chr10:82375514 A/G cg03086067 chr10:82368399 SH2D4B -0.23 -4.54 -0.38 1.33e-5 Capecitabine sensitivity; TGCT cis rs2153535 0.580 rs6921036 chr6:8455400 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs8020441 0.945 rs57182174 chr14:51167938 A/T cg04730355 chr14:51134070 SAV1 0.71 5.83 0.46 4.42e-8 Cognitive performance; TGCT cis rs12142240 0.621 rs66828173 chr1:46818166 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT trans rs629535 0.783 rs538832 chr8:70033817 A/G cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg06873352 chr17:61820015 STRADA 0.55 5.69 0.46 8.57e-8 Prudent dietary pattern; TGCT cis rs1322512 1.000 rs1405694 chr6:152946561 C/T cg03415253 chr6:152958462 SYNE1 -0.49 -4.45 -0.37 1.93e-5 Tonometry; TGCT cis rs2072499 0.966 rs2842869 chr1:156160696 A/G cg25208724 chr1:156163844 SLC25A44 1.14 16.72 0.83 1.43e-33 Testicular germ cell tumor; TGCT cis rs2115536 0.967 rs3826008 chr15:80189805 G/T cg00225070 chr15:80189496 MTHFS 0.61 5.53 0.44 1.82e-7 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7255045 0.788 rs6511843 chr19:12955544 A/C cg23899408 chr19:12877188 HOOK2 -0.59 -4.93 -0.41 2.55e-6 Mean corpuscular volume; TGCT cis rs7246657 0.943 rs1373991 chr19:37838911 T/C cg03233940 chr19:37894644 NA -0.34 -4.49 -0.37 1.59e-5 Coronary artery calcification; TGCT cis rs9814567 0.896 rs6790338 chr3:134208167 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9399135 1.000 rs4896130 chr6:135355118 C/T cg24558204 chr6:135376177 HBS1L 0.46 4.6 0.38 1.03e-5 Red blood cell count; TGCT cis rs12421382 0.659 rs1371330 chr11:109382692 G/T cg16359550 chr11:109292809 C11orf87 0.4 4.5 0.37 1.54e-5 Schizophrenia; TGCT cis rs6089829 0.926 rs6062395 chr20:61667904 A/G cg03213289 chr20:61660250 NA 0.67 9.59 0.65 1.22e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs422249 0.504 rs174538 chr11:61560081 G/A cg19610905 chr11:61596333 FADS2 -0.98 -9.07 -0.63 2.23e-15 Trans fatty acid levels; TGCT cis rs7027203 0.576 rs7862149 chr9:96546778 A/G cg13679303 chr9:96623674 NA 0.53 7.61 0.56 6.13e-12 DNA methylation (variation); TGCT cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg03760483 chr17:6899297 ALOX12 0.47 5.47 0.44 2.33e-7 Tonsillectomy; TGCT cis rs6570726 0.967 rs413880 chr6:145804822 G/A cg23711669 chr6:146136114 FBXO30 0.66 6.08 0.48 1.37e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs2370759 1.000 rs16933243 chr10:32615135 T/C cg01819863 chr10:32635814 EPC1 1.03 10.07 0.67 8.33e-18 Sexual dysfunction (female); TGCT cis rs765787 0.530 rs10851423 chr15:45515950 G/A cg24006582 chr15:45444508 DUOX1 0.25 5.33 0.43 4.46e-7 Uric acid levels; TGCT cis rs7178572 1.000 rs1565756 chr15:77741640 G/A cg15453836 chr15:77711506 NA -0.41 -4.71 -0.39 6.5e-6 Type 2 diabetes; TGCT cis rs72627509 0.904 rs17081933 chr4:57822869 T/A cg26694713 chr4:57773883 REST 0.71 6.26 0.49 5.63e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs826838 0.967 rs826870 chr12:39120250 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.76 -0.57 2.68e-12 Heart rate; TGCT cis rs4819052 0.851 rs2255766 chr21:46683777 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2637266 0.846 rs2637260 chr10:78320346 C/T cg18941641 chr10:78392320 NA -0.37 -4.48 -0.37 1.67e-5 Pulmonary function; TGCT cis rs13088645 0.729 rs7620040 chr3:134163082 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.65 -6.64 -0.51 8.92e-10 Coronary artery disease; TGCT cis rs524281 0.692 rs11227395 chr11:65829637 A/C cg00563793 chr11:65837595 PACS1 0.53 4.75 0.39 5.6e-6 Electroencephalogram traits; TGCT trans rs8073060 0.586 rs225298 chr17:33923946 T/G cg19694781 chr19:47549865 TMEM160 -0.61 -13.7 -0.78 1.39e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs6570726 0.764 rs376257 chr6:145862949 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs17384381 0.953 rs12139958 chr1:85842112 A/G cg16011679 chr1:85725395 C1orf52 0.84 6.52 0.51 1.6e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg07507251 chr3:52567010 NT5DC2 0.46 6.51 0.5 1.66e-9 Bipolar disorder; TGCT cis rs7027930 0.517 rs17344772 chr9:549845 A/G cg13877502 chr9:707387 KANK1 0.5 4.55 0.38 1.28e-5 Pulmonary function decline; TGCT cis rs2455799 0.613 rs6802048 chr3:15883933 A/G cg16303742 chr3:15540471 COLQ -0.24 -4.44 -0.37 1.99e-5 Mean platelet volume; TGCT cis rs2688608 0.839 rs2675662 chr10:75599127 A/G cg19442545 chr10:75533431 FUT11 0.31 4.56 0.38 1.23e-5 Inflammatory bowel disease; TGCT cis rs12682352 0.602 rs6988939 chr8:8666916 C/T cg06636001 chr8:8085503 FLJ10661 0.61 5.1 0.42 1.26e-6 Neuroticism; TGCT cis rs12477438 1.000 rs1922624 chr2:99909958 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.82 -6.44 -0.5 2.4e-9 Chronic sinus infection; TGCT cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg08219700 chr8:58056026 NA 0.4 4.92 0.4 2.67e-6 Developmental language disorder (linguistic errors); TGCT cis rs2637266 0.935 rs1907323 chr10:78336015 C/T cg18941641 chr10:78392320 NA 0.41 5.21 0.42 7.76e-7 Pulmonary function; TGCT cis rs3820068 0.603 rs72647120 chr1:15956769 G/T cg05660106 chr1:15850417 CASP9 0.84 8.28 0.6 1.64e-13 Systolic blood pressure; TGCT cis rs2439831 0.850 rs558656 chr15:43723514 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs546131 0.642 rs473848 chr11:34851977 A/C cg06937548 chr11:34938143 PDHX;APIP 0.52 4.55 0.38 1.28e-5 Lung disease severity in cystic fibrosis; TGCT cis rs61990749 0.597 rs2299930 chr14:78163722 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.67 -4.73 -0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs2594989 0.943 rs77630528 chr3:11314041 A/G cg00170343 chr3:11313890 ATG7 0.66 4.75 0.39 5.58e-6 Circulating chemerin levels; TGCT cis rs6089584 0.888 rs6089623 chr20:60615759 A/G cg16423285 chr20:60520624 NA -0.61 -6.57 -0.51 1.23e-9 Body mass index; TGCT cis rs11252926 0.537 rs4554800 chr10:458477 G/T cg20256804 chr10:444983 DIP2C 0.21 4.7 0.39 6.83e-6 Psychosis in Alzheimer's disease; TGCT cis rs7772486 0.790 rs2256998 chr6:146207657 A/C cg23711669 chr6:146136114 FBXO30 0.89 10.18 0.67 4.61e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs10501293 0.703 rs4237640 chr11:42990542 G/A cg03447554 chr11:43094025 NA 0.44 6.45 0.5 2.25e-9 Cognitive performance; TGCT cis rs801193 0.967 rs1110414 chr7:66205582 A/G cg00343986 chr7:65444356 GUSB 0.24 5.25 0.43 6.3e-7 Aortic root size; TGCT cis rs7666738 0.570 rs10032272 chr4:99095601 T/C cg18180107 chr4:99064573 C4orf37 0.51 4.58 0.38 1.09e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs7582180 0.739 rs11687352 chr2:100919888 A/C cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.45e-6 Intelligence (multi-trait analysis); TGCT cis rs8016982 1.000 rs12147118 chr14:81652975 A/C cg01989461 chr14:81687754 GTF2A1 -0.62 -5.14 -0.42 1.03e-6 Schizophrenia; TGCT cis rs7547997 0.517 rs6687405 chr1:158240757 T/G cg07950803 chr1:158223934 CD1A 0.31 4.69 0.39 7.1e-6 QRS duration; TGCT cis rs9733 0.596 rs72702570 chr1:150688196 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs2072499 0.778 rs2247476 chr1:156190280 C/A cg25208724 chr1:156163844 SLC25A44 0.94 8.7 0.62 1.73e-14 Testicular germ cell tumor; TGCT cis rs6424115 0.793 rs2502998 chr1:24198327 T/A cg15997130 chr1:24165203 NA 0.86 9.53 0.65 1.76e-16 Immature fraction of reticulocytes; TGCT cis rs2820315 1.000 rs2820313 chr1:201870221 A/G cg12730843 chr1:201915899 LMOD1 -0.27 -4.85 -0.4 3.64e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT trans rs4332037 0.802 rs12113633 chr7:1932936 G/A cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs17030434 1.000 rs6853522 chr4:154706220 A/C cg14289246 chr4:154710475 SFRP2 1.03 8.07 0.59 5.05e-13 Electrocardiographic conduction measures; TGCT cis rs7582180 0.764 rs1946799 chr2:100921136 C/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs2075371 0.796 rs1646645 chr7:134012232 G/T cg11752832 chr7:134001865 SLC35B4 -0.72 -6.22 -0.49 6.92e-9 Mean platelet volume; TGCT cis rs9308731 0.583 rs7567184 chr2:111931072 C/G cg04202892 chr2:111875749 ACOXL 0.45 5.11 0.42 1.21e-6 Chronic lymphocytic leukemia; TGCT cis rs208520 0.690 rs12213581 chr6:66735818 T/C cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs637571 0.557 rs1204649 chr11:65702776 A/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.62 6.32 0.49 4.22e-9 Eosinophil percentage of white cells; TGCT cis rs7582180 0.739 rs10195793 chr2:100925803 A/G cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg07092213 chr7:1199455 ZFAND2A -0.43 -4.64 -0.38 8.8e-6 Longevity;Endometriosis; TGCT cis rs10744422 0.841 rs10847742 chr12:123289395 A/G cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs3806843 0.607 rs246044 chr5:140330656 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.11e-5 Depressive symptoms (multi-trait analysis); TGCT trans rs4650994 0.525 rs2493865 chr1:178545016 G/A cg05059571 chr16:84539110 KIAA1609 0.53 10.7 0.69 2.54e-19 HDL cholesterol levels;HDL cholesterol; TGCT cis rs8177253 1.000 rs8177253 chr3:133480192 A/G cg16414030 chr3:133502952 NA 0.63 10.04 0.67 1.02e-17 Iron status biomarkers; TGCT cis rs10779751 1.000 rs4845858 chr1:11304720 C/T cg08854313 chr1:11322531 MTOR 0.94 10.52 0.69 6.72e-19 Body mass index; TGCT cis rs9814567 1.000 rs7645295 chr3:134307734 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1218582 0.710 rs7553195 chr1:154837796 T/C cg06221963 chr1:154839813 KCNN3 -0.8 -14.7 -0.8 6.11e-29 Prostate cancer; TGCT cis rs1538970 0.924 rs11211118 chr1:45930270 A/C cg05343316 chr1:45956843 TESK2 0.75 6.27 0.49 5.48e-9 Platelet count; TGCT cis rs7698623 0.717 rs4693193 chr4:88797992 T/C cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs494562 0.730 rs9450270 chr6:86114766 A/G cg27039625 chr6:86159096 NT5E 0.53 4.55 0.38 1.24e-5 Blood metabolite levels;Metabolic traits; TGCT cis rs17125944 0.505 rs75194546 chr14:53212069 A/C cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs6681544 0.512 rs17472472 chr1:82479318 T/C cg04226724 chr1:82268649 LPHN2 0.48 5.21 0.42 7.77e-7 Metabolite levels (X-11787); TGCT cis rs3820068 0.581 rs111699992 chr1:15927158 G/A cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs2228479 1.000 rs117406136 chr16:89974605 C/T cg06558623 chr16:89946397 TCF25 0.58 6.67 0.51 7.45e-10 Skin colour saturation; TGCT cis rs763014 0.865 rs710924 chr16:633353 T/C cg00908189 chr16:619842 PIGQ 0.87 10.2 0.68 4.14e-18 Height; TGCT cis rs7829975 0.577 rs7816329 chr8:8543843 G/A cg08975724 chr8:8085496 FLJ10661 -0.51 -4.44 -0.37 1.96e-5 Mood instability; TGCT cis rs7428 0.527 rs7607284 chr2:85547376 C/G cg24342717 chr2:85555507 TGOLN2 -0.49 -7.81 -0.57 2.04e-12 Ear protrusion; TGCT cis rs7209700 0.547 rs61131650 chr17:45344327 G/A cg21624342 chr17:45890973 OSBPL7 0.19 4.71 0.39 6.52e-6 IgG glycosylation; TGCT cis rs72843506 0.722 rs74255392 chr17:20329052 A/G cg18052601 chr17:19850474 AKAP10 0.28 4.6 0.38 1.02e-5 Schizophrenia; TGCT cis rs28595532 0.920 rs114792862 chr4:119759938 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs114722517 chr4:99042061 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2857078 0.745 rs4793085 chr17:42320732 A/C cg13607699 chr17:42295918 UBTF -0.97 -10.63 -0.69 3.63e-19 Red cell distribution width;Reticulocyte count; TGCT cis rs6582630 0.554 rs7299735 chr12:38450890 A/C cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.8 -0.62 9.55e-15 Bipolar disorder; TGCT cis rs7760949 0.963 rs9367699 chr6:13894635 A/C cg27413430 chr6:13925136 RNF182 0.54 5.01 0.41 1.85e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs727563 0.635 rs5751141 chr22:42107745 A/G cg13695892 chr22:41940480 POLR3H 0.88 8.57 0.61 3.38e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6570726 0.791 rs11155433 chr6:145907831 A/G cg13319975 chr6:146136371 FBXO30 0.53 4.76 0.39 5.36e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1960156 1.000 rs1960156 chr16:12404016 C/T cg08104224 chr16:11588532 NA 0.25 4.48 0.37 1.67e-5 Subjective well-being; TGCT cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg18305652 chr10:134549665 INPP5A 0.35 5.55 0.45 1.66e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6543140 1.000 rs6543140 chr2:103074274 G/T cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs4242434 0.927 rs2291234 chr8:22464390 T/C cg03733263 chr8:22462867 KIAA1967 1.13 20.13 0.88 6.96e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs8072100 0.713 rs8075058 chr17:45482857 A/G cg08085267 chr17:45401833 C17orf57 -0.52 -5.78 -0.46 5.78e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs611744 0.647 rs7016198 chr8:109262752 G/A cg21045802 chr8:109455806 TTC35 0.7 7.05 0.54 1.07e-10 Dupuytren's disease; TGCT cis rs7044106 0.791 rs2416798 chr9:123480603 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 7.1 0.54 8.41e-11 Hip circumference adjusted for BMI; TGCT cis rs2762353 0.603 rs4145221 chr6:25763192 A/G cg03264133 chr6:25882463 NA 0.49 4.87 0.4 3.28e-6 Blood metabolite levels; TGCT cis rs7119 0.717 rs12912386 chr15:77817640 T/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs11122272 0.735 rs973253 chr1:231520874 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs17376456 0.809 rs10476602 chr5:93445255 T/C cg21475434 chr5:93447410 FAM172A 0.58 4.57 0.38 1.16e-5 Diabetic retinopathy; TGCT cis rs72615157 0.716 rs75779608 chr7:99768957 C/T cg00814883 chr7:100076585 TSC22D4 -0.56 -5.22 -0.42 7.46e-7 Lung function (FEV1/FVC); TGCT cis rs9942416 0.601 rs40059 chr5:74964582 A/G cg19683494 chr5:74908142 NA -0.62 -6.9 -0.53 2.32e-10 Age-related disease endophenotypes; TGCT trans rs1814175 0.817 rs7929173 chr11:49944007 T/C cg03929089 chr4:120376271 NA -0.7 -7.87 -0.58 1.51e-12 Height; TGCT cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg10465839 chr16:1584050 IFT140;TMEM204 -0.31 -5.2 -0.42 8.13e-7 Coronary artery disease; TGCT cis rs6540559 0.543 rs650728 chr1:210433351 C/T cg22029157 chr1:209979665 IRF6 0.62 4.45 0.37 1.92e-5 Cleft lip with or without cleft palate; TGCT cis rs13256369 0.901 rs12681298 chr8:8566235 A/G cg06671706 chr8:8559999 CLDN23 -0.34 -4.61 -0.38 9.76e-6 Obesity-related traits; TGCT cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg20637647 chr7:64974828 NA 0.88 5.12 0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs7666738 0.791 rs1426661 chr4:98874303 C/G cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17401966 0.931 rs10492972 chr1:10353112 A/G cg19773385 chr1:10388646 KIF1B -0.2 -4.44 -0.37 1.94e-5 Hepatocellular carcinoma; TGCT cis rs2361718 0.500 rs8068856 chr17:78100731 A/G cg09238746 chr17:78121135 EIF4A3 -1.09 -10.19 -0.68 4.3e-18 Yeast infection; TGCT cis rs7635838 0.859 rs6768611 chr3:11434465 G/A cg00170343 chr3:11313890 ATG7 0.63 6.18 0.49 8.64e-9 HDL cholesterol; TGCT cis rs4886920 0.640 rs11072674 chr15:78081658 A/G cg25212270 chr15:78015279 NA 0.24 4.97 0.41 2.14e-6 Neuroticism; TGCT cis rs7618915 1.000 rs59565798 chr3:52307169 G/A cg07507251 chr3:52567010 NT5DC2 0.46 6.2 0.49 7.59e-9 Bipolar disorder; TGCT cis rs7617773 0.539 rs12486935 chr3:48390164 C/T cg11946769 chr3:48343235 NME6 0.57 4.89 0.4 3.05e-6 Coronary artery disease; TGCT cis rs3741404 1.000 rs3741404 chr11:63999240 G/C cg01727686 chr11:63997306 NUDT22;DNAJC4 0.22 4.57 0.38 1.14e-5 Platelet count; TGCT cis rs11203032 0.831 rs7076185 chr10:90923524 G/A cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs7043114 0.525 rs2516567 chr9:95187418 C/T cg14631576 chr9:95140430 CENPP -0.27 -4.56 -0.38 1.22e-5 Height; TGCT cis rs6831352 0.918 rs4699714 chr4:100060538 A/G cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg23719950 chr11:63933701 MACROD1 -0.71 -5.93 -0.47 2.77e-8 Attention deficit hyperactivity disorder; TGCT cis rs35306767 0.761 rs34480046 chr10:1027440 A/G cg18964960 chr10:1102726 WDR37 0.74 5.31 0.43 4.97e-7 Eosinophil percentage of granulocytes; TGCT cis rs7647973 0.710 rs6446285 chr3:49626306 G/A cg03060546 chr3:49711283 APEH 0.62 4.83 0.4 4e-6 Menarche (age at onset); TGCT cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg10802521 chr3:52805072 NEK4 -0.66 -7.8 -0.57 2.22e-12 Bipolar disorder; TGCT cis rs11190604 0.767 rs11190534 chr10:102190930 G/A cg16005271 chr10:102321736 NA 0.45 4.7 0.39 6.81e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7918232 0.882 rs6415983 chr10:27357211 A/G cg14442939 chr10:27389572 ANKRD26 0.68 4.72 0.39 6.38e-6 Breast cancer; TGCT cis rs1799949 0.683 rs55737636 chr17:41264739 C/T cg05368731 chr17:41323189 NBR1 1.06 11.61 0.72 1.55e-21 Menopause (age at onset); TGCT cis rs11209002 0.545 rs2093332 chr1:67531974 G/A cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs858239 0.699 rs1881201 chr7:23194013 C/T cg05407003 chr7:23246146 NA 0.27 4.59 0.38 1.07e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs10892173 0.765 rs1892902 chr11:117669794 T/G cg07621104 chr11:117668040 DSCAML1 0.5 5.39 0.44 3.47e-7 Myopia; TGCT cis rs10992471 0.528 rs1535754 chr9:95201917 T/G cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs968567 0.559 rs174544 chr11:61567753 C/A cg19610905 chr11:61596333 FADS2 -1.07 -11.36 -0.71 6.23e-21 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs11190604 0.666 rs7084768 chr10:102200497 T/C cg23241863 chr10:102295624 HIF1AN -0.65 -4.9 -0.4 2.9e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12134133 0.962 rs7516416 chr1:207414395 G/A cg02152968 chr1:207494213 CD55 0.6 4.65 0.39 8.43e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs13064447 0.870 rs7631468 chr3:12754997 A/G cg20675869 chr3:12750130 NA 0.19 4.7 0.39 6.7e-6 Major depression and alcohol dependence; TGCT cis rs7010267 0.746 rs13250753 chr8:119906692 C/G cg17171407 chr8:119960777 TNFRSF11B -0.29 -5.04 -0.41 1.59e-6 Total body bone mineral density (age 45-60); TGCT cis rs1577917 1.000 rs12201880 chr6:86627007 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs8038465 0.874 rs11574497 chr15:74004557 A/T cg15420318 chr15:73925796 NPTN 0.55 4.92 0.4 2.69e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7714584 1.000 rs4560537 chr5:150262586 G/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs8051149 0.688 rs12444533 chr16:87869711 C/T cg01412419 chr16:87856264 NA 0.5 6.07 0.48 1.43e-8 Blood metabolite levels; TGCT cis rs6504950 0.566 rs12937360 chr17:53046298 C/T cg19360675 chr17:53046073 COX11;STXBP4 0.56 5.41 0.44 3.06e-7 Breast cancer; TGCT cis rs2562456 0.876 rs62110202 chr19:21754601 C/T cg01304269 chr19:21688519 ZNF429 0.57 4.45 0.37 1.88e-5 Pain; TGCT cis rs2153535 0.580 rs9505457 chr6:8479142 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs5758659 0.714 rs7245 chr22:42481849 G/A cg15557168 chr22:42548783 NA 0.17 4.46 0.37 1.82e-5 Cognitive function; TGCT cis rs7786808 0.741 rs11767875 chr7:158228923 A/G cg01191920 chr7:158217561 PTPRN2 -0.44 -6.64 -0.51 8.76e-10 Obesity-related traits; TGCT cis rs7772486 0.790 rs2250387 chr6:146205233 C/T cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9910055 0.529 rs425038 chr17:42182028 T/C cg13607699 chr17:42295918 UBTF -0.65 -5.55 -0.45 1.64e-7 Total body bone mineral density; TGCT cis rs9303401 0.659 rs7210700 chr17:56668186 G/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs4460629 0.742 rs11264314 chr1:155078423 C/G cg23973274 chr1:155060172 NA -0.26 -4.66 -0.39 8.1e-6 Serum magnesium levels; TGCT cis rs7552404 0.961 rs1767458 chr1:76219155 A/G cg10523679 chr1:76189770 ACADM 0.82 8.79 0.62 1.05e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs523522 0.923 rs2235217 chr12:120884328 C/T cg12219531 chr12:120966889 COQ5 0.79 6.99 0.53 1.47e-10 High light scatter reticulocyte count; TGCT cis rs4805272 0.512 rs11879141 chr19:29320335 G/A cg12756686 chr19:29218302 NA 0.63 4.53 0.38 1.34e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs7552404 1.000 rs7513559 chr1:76173744 A/G cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs797680 0.856 rs2031225 chr1:93786714 A/G cg17826107 chr1:92977322 EVI5 0.22 5.05 0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6964587 1.000 rs6952671 chr7:91597934 C/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs9296661 0.680 rs6923760 chr6:51685228 G/T cg00593404 chr6:52377740 TRAM2 0.27 4.56 0.38 1.22e-5 Weight loss (gastric bypass surgery); TGCT cis rs12188164 0.965 rs11743639 chr5:450710 C/T cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg06634786 chr22:41940651 POLR3H -0.9 -8.58 -0.61 3.3e-14 Vitiligo; TGCT cis rs763121 0.853 rs5757196 chr22:39039855 G/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg03760483 chr17:6899297 ALOX12 0.47 5.38 0.44 3.53e-7 Tonsillectomy; TGCT cis rs225245 0.817 rs1476553 chr17:33994566 C/T cg05299278 chr17:33885742 SLFN14 0.21 4.52 0.38 1.44e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs453301 0.631 rs13250781 chr8:8793343 T/G cg06636001 chr8:8085503 FLJ10661 -0.69 -5.92 -0.47 2.97e-8 Joint mobility (Beighton score); TGCT cis rs7043114 0.563 rs10820988 chr9:95317008 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -5.26 -0.43 6.11e-7 Height; TGCT cis rs9926296 0.605 rs886952 chr16:89836781 G/A cg27121462 chr16:89883253 FANCA 0.75 8.07 0.59 5.21e-13 Vitiligo; TGCT cis rs611744 0.573 rs674580 chr8:109251690 C/G cg21045802 chr8:109455806 TTC35 0.83 8.71 0.62 1.57e-14 Dupuytren's disease; TGCT cis rs10504229 0.636 rs115738451 chr8:58055133 A/T cg21724239 chr8:58056113 NA 0.48 5.17 0.42 9.18e-7 Developmental language disorder (linguistic errors); TGCT cis rs1903068 0.785 rs12331538 chr4:55998086 A/C cg09978860 chr4:56023921 NA 0.56 6.24 0.49 6.22e-9 Endometriosis; TGCT cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg03161606 chr19:29218774 NA 0.56 6.1 0.48 1.26e-8 Methadone dose in opioid dependence; TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs7552404 1.000 rs7552404 chr1:76135946 A/G cg22875332 chr1:76189707 ACADM 0.79 9.9 0.66 2.25e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.830 rs28887893 chr4:98963006 G/A cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs367615 0.704 rs4320313 chr5:108828687 A/G cg17395555 chr5:108820864 NA 0.32 6.11 0.48 1.16e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6912958 0.781 rs9444512 chr6:88223397 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs950169 0.810 rs62029594 chr15:84955252 T/C cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs6723226 0.881 rs10181198 chr2:32686582 A/G cg02381751 chr2:32503542 YIPF4 0.54 4.95 0.41 2.36e-6 Intelligence (multi-trait analysis); TGCT trans rs9929218 0.551 rs2274240 chr16:68725486 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.61 7.97 0.58 8.72e-13 Colorectal cancer; TGCT cis rs76419734 0.510 rs2553461 chr4:106731410 A/G cg24545054 chr4:106630052 GSTCD;INTS12 -0.7 -4.57 -0.38 1.18e-5 Post bronchodilator FEV1; TGCT cis rs6921919 0.583 rs6922169 chr6:28382932 G/A cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs8014252 0.708 rs8010473 chr14:70988993 G/C cg11204974 chr14:71022665 NA -0.53 -4.46 -0.37 1.79e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs137603 0.644 rs137619 chr22:39706360 A/C cg01093212 chr22:39715156 SNORD43;RPL3 -0.55 -5.07 -0.41 1.41e-6 Primary biliary cholangitis; TGCT cis rs67311347 0.911 rs58282210 chr3:40417943 C/T cg13409248 chr3:40428643 ENTPD3 0.55 4.49 0.37 1.61e-5 Renal cell carcinoma; TGCT cis rs6840360 0.550 rs6853955 chr4:152510806 G/A cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs9346649 0.654 rs35453512 chr6:168491906 C/G cg02770688 chr6:168491649 NA 0.34 6.06 0.48 1.53e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs9318086 0.712 rs1886970 chr13:24440498 T/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.77 8.12 0.59 3.92e-13 Myopia (pathological); TGCT trans rs365060 0.908 rs260692 chr2:109581319 T/C cg13735819 chr19:2253850 JSRP1 -0.7 -6.64 -0.51 8.83e-10 Beard thickness; TGCT cis rs12291225 0.679 rs34238445 chr11:14315915 C/T cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs9660180 0.967 rs12040325 chr1:1702436 G/A cg17747265 chr1:1875780 NA -0.38 -7.18 -0.54 5.61e-11 Body mass index; TGCT cis rs56104184 0.775 rs73061689 chr19:49397214 C/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs17376456 0.877 rs13165147 chr5:93422214 G/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs7607369 0.648 rs7599984 chr2:219656713 T/G cg02176678 chr2:219576539 TTLL4 -0.47 -6.0 -0.47 1.98e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs698813 0.604 rs12712916 chr2:44482099 A/C cg00619915 chr2:44497795 NA -0.21 -4.98 -0.41 2.12e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs9811920 0.683 rs793502 chr3:99588417 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.43 -5.13 -0.42 1.1e-6 Axial length; TGCT trans rs7819412 0.703 rs2409713 chr8:11009797 C/T cg15556689 chr8:8085844 FLJ10661 -0.79 -7.01 -0.53 1.33e-10 Triglycerides; TGCT cis rs6866344 0.697 rs11743893 chr5:178125194 C/T cg03877680 chr5:178157825 ZNF354A 0.78 5.91 0.47 3.06e-8 Neutrophil percentage of white cells; TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg02493798 chr17:6899577 ALOX12 0.43 4.65 0.39 8.35e-6 Tonsillectomy; TGCT trans rs629535 0.862 rs655028 chr8:70049047 T/C cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs904251 0.861 rs1757180 chr6:37486145 T/C cg08126542 chr6:37504118 NA -0.43 -5.78 -0.46 5.59e-8 Cognitive performance; TGCT cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs6570726 0.791 rs6923074 chr6:145893332 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2013441 1.000 rs2703772 chr17:20131453 C/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs12477438 0.520 rs720229 chr2:99704273 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.76 7.27 0.55 3.46e-11 Chronic sinus infection; TGCT cis rs7017914 0.905 rs3110254 chr8:71937862 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs9467773 0.838 rs3734540 chr6:26463321 A/C cg09904177 chr6:26538194 HMGN4 0.56 5.33 0.43 4.39e-7 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs7552404 0.807 rs2066183 chr1:76153745 A/G cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2067615 0.579 rs1073261 chr12:107135942 A/G cg15890332 chr12:107067104 RFX4 0.3 5.93 0.47 2.85e-8 Heart rate; TGCT cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.716 rs56216512 chr15:76686936 T/C cg26408565 chr15:76604113 ETFA -0.42 -5.43 -0.44 2.85e-7 Blood metabolite levels; TGCT cis rs911555 0.504 rs4906340 chr14:104076645 G/A cg26031613 chr14:104095156 KLC1 -0.63 -5.88 -0.47 3.62e-8 Intelligence (multi-trait analysis); TGCT cis rs1256061 0.654 rs1256040 chr14:64738394 G/A cg21174375 chr14:64681225 SYNE2 0.2 4.43 0.37 2.01e-5 Hemoglobin concentration;Red blood cell count;Hematocrit; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg15242686 chr22:24348715 GSTTP1 0.47 5.24 0.43 6.8e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs4919694 1.000 rs80327774 chr10:104656671 T/C cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs8103278 0.507 rs3745802 chr19:46271177 G/T cg11657440 chr19:46296263 DMWD 0.75 7.96 0.58 9.31e-13 Coronary artery disease; TGCT cis rs2228479 0.850 rs17226498 chr16:89840631 T/C cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT trans rs1005277 0.565 rs2474565 chr10:38380828 A/G cg17830980 chr10:43048298 ZNF37B -0.87 -11.11 -0.71 2.53e-20 Extrinsic epigenetic age acceleration; TGCT trans rs1814175 0.645 rs1721995 chr11:49915488 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT trans rs9990220 0.586 rs12106673 chr3:112061731 G/A cg09134205 chr7:154003215 DPP6 -0.41 -7.52 -0.56 9.7e-12 Eosinophil percentage of white cells; TGCT cis rs644799 0.511 rs12791736 chr11:95475399 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.65 6.24 0.49 6.21e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2760061 0.583 rs708121 chr1:228208257 A/G cg02753203 chr1:228287806 NA 0.39 7.81 0.57 2.08e-12 Diastolic blood pressure; TGCT cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.643 rs4674305 chr2:219293326 C/T cg02176678 chr2:219576539 TTLL4 0.38 5.52 0.44 1.88e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7267979 1.000 rs2482911 chr20:25395528 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8017423 0.904 rs11623741 chr14:90804474 C/T cg04374321 chr14:90722782 PSMC1 0.74 7.17 0.54 5.87e-11 Mortality in heart failure; TGCT cis rs78487399 0.710 rs6731998 chr2:43677273 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs6951245 0.580 rs77101766 chr7:1122438 A/G cg13565492 chr6:43139072 SRF -0.81 -7.56 -0.56 7.76e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9911578 1.000 rs302859 chr17:56693132 C/T cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs634534 0.622 rs552130 chr11:65732800 T/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 5.18 0.42 8.63e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs17473412 1.000 rs11748094 chr5:122698695 T/A cg15125798 chr5:122621645 NA -0.57 -5.16 -0.42 9.64e-7 Total body bone mineral density; TGCT cis rs11122272 0.735 rs2486736 chr1:231521478 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.62 5.69 0.45 8.78e-8 Hemoglobin concentration; TGCT cis rs6840360 0.550 rs11723438 chr4:152531801 C/T cg17479576 chr4:152424074 FAM160A1 0.74 7.96 0.58 9.36e-13 Intelligence (multi-trait analysis); TGCT trans rs7824557 0.569 rs2409718 chr8:11012977 C/T cg15556689 chr8:8085844 FLJ10661 -0.86 -8.59 -0.61 3.03e-14 Retinal vascular caliber; TGCT cis rs7833790 0.700 rs7825180 chr8:82723991 T/A cg27398817 chr8:82754497 SNX16 -0.67 -5.34 -0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg00343986 chr7:65444356 GUSB 0.26 6.06 0.48 1.48e-8 Aortic root size; TGCT cis rs459571 0.959 rs392134 chr9:136909008 G/A cg13789015 chr9:136890014 NCRNA00094 0.42 7.78 0.57 2.44e-12 Platelet distribution width; TGCT cis rs2204008 0.840 rs11181795 chr12:38401129 A/G cg13010199 chr12:38710504 ALG10B 0.59 4.68 0.39 7.35e-6 Bladder cancer; TGCT cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.74 0.39 5.8e-6 Schizophrenia; TGCT cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg24829409 chr8:58192753 C8orf71 -0.55 -5.17 -0.42 9.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7681440 0.904 rs3806789 chr4:90759556 C/T cg20003494 chr4:90757398 SNCA -0.61 -5.78 -0.46 5.59e-8 Dementia with Lewy bodies; TGCT cis rs2486288 0.656 rs62026703 chr15:45569929 G/T cg26924012 chr15:45694286 SPATA5L1 -0.78 -7.55 -0.56 8e-12 Glomerular filtration rate; TGCT trans rs208515 0.525 rs12204452 chr6:66680325 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs939658 0.935 rs34859518 chr15:79450422 A/G cg17916960 chr15:79447300 NA -0.52 -8.31 -0.6 1.45e-13 Refractive error; TGCT cis rs7666738 0.830 rs13148913 chr4:99009732 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10779751 1.000 rs718206 chr1:11294474 T/A cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs2721173 0.619 rs997258 chr8:145903077 C/A cg11211951 chr8:145729740 GPT -0.23 -5.11 -0.42 1.2e-6 Educational attainment;Cognitive ability (multi-trait analysis);Intelligence (multi-trait analysis); TGCT cis rs617219 0.710 rs10805925 chr5:78539399 A/G cg23514016 chr5:78407564 BHMT 0.3 4.58 0.38 1.1e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg03264133 chr6:25882463 NA 0.49 4.55 0.38 1.24e-5 Intelligence (multi-trait analysis); TGCT cis rs73815153 0.744 rs28369005 chr5:180459580 A/G cg00299286 chr5:180478185 BTNL9 0.87 4.98 0.41 2.08e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs344364 0.602 rs12719796 chr16:1921197 A/G cg07677296 chr16:1877182 HAGH;FAHD1 0.52 4.44 0.37 1.99e-5 Glomerular filtration rate in chronic kidney disease; TGCT cis rs2439831 1.000 rs2467739 chr15:43740196 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs12148488 0.763 rs4886648 chr15:75308837 G/A cg10253484 chr15:75165896 SCAMP2 -0.6 -5.24 -0.43 6.58e-7 Caffeine consumption; TGCT cis rs1552244 0.882 rs56332224 chr3:10037321 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs10465746 0.935 rs11807807 chr1:84424071 C/T cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs7943203 0.568 rs170548 chr11:108234836 A/C cg04873221 chr11:107992290 ACAT1 -0.59 -5.0 -0.41 1.87e-6 Red blood cell count;Mean corpuscular volume; TGCT cis rs9733 0.519 rs72704603 chr1:150707992 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.59 0.38 1.05e-5 Tonsillectomy; TGCT cis rs6121246 0.529 rs7261354 chr20:30202414 T/C cg21427119 chr20:30132790 HM13 -0.39 -5.61 -0.45 1.25e-7 Mean corpuscular hemoglobin; TGCT cis rs6754311 0.551 rs10928545 chr2:136501840 A/G cg07169764 chr2:136633963 MCM6 -0.71 -6.37 -0.5 3.33e-9 Mosquito bite size; TGCT cis rs7267979 1.000 rs2259926 chr20:25281733 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs789852 0.867 rs789846 chr3:194322999 T/C cg18000598 chr3:194342907 TMEM44 -0.81 -5.31 -0.43 4.83e-7 QT interval; TGCT cis rs7264396 0.790 rs6060518 chr20:34217309 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.67 -0.39 7.62e-6 Total cholesterol levels; TGCT cis rs6964587 0.900 rs62467794 chr7:91850578 C/T cg17063962 chr7:91808500 NA 0.86 8.48 0.61 5.67e-14 Breast cancer; TGCT cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs4689388 0.890 rs13130845 chr4:6297646 A/C cg14416269 chr4:6271139 WFS1 0.38 4.94 0.41 2.47e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs877282 0.853 rs7079299 chr10:756455 A/G cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs11098499 0.863 rs7669520 chr4:120515278 T/C cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs1420338 0.933 rs731844 chr7:34150264 C/T cg01275685 chr7:34179230 BMPER -0.26 -4.84 -0.4 3.75e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg23131131 chr22:24373011 LOC391322 -0.73 -7.0 -0.53 1.46e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7927592 0.763 rs624003 chr11:68231240 C/T cg16797656 chr11:68205561 LRP5 0.26 4.54 0.38 1.29e-5 Total body bone mineral density; TGCT cis rs4665809 1.000 rs1550381 chr2:26266946 A/G cg25036284 chr2:26402008 FAM59B -0.56 -4.85 -0.4 3.62e-6 Gut microbiome composition (summer); TGCT cis rs6992820 0.592 rs3808391 chr8:56790649 A/G cg06880721 chr8:56792545 LYN -0.72 -6.44 -0.5 2.42e-9 Mean platelet volume; TGCT cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg24675658 chr1:53192096 ZYG11B 0.74 8.68 0.61 1.87e-14 Monocyte count; TGCT cis rs9810089 0.843 rs834304 chr3:136111658 G/T cg12473912 chr3:136751656 NA 0.37 5.15 0.42 9.8e-7 Gestational age at birth (child effect); TGCT cis rs7666738 0.830 rs35939134 chr4:98980311 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg03806693 chr22:41940476 POLR3H 1.11 12.56 0.75 7.44e-24 Vitiligo; TGCT cis rs10256972 0.521 rs10280960 chr7:1103697 A/G cg03188948 chr7:1209495 NA 0.47 5.83 0.46 4.5e-8 Longevity;Endometriosis; TGCT cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg08280861 chr8:58055591 NA 0.38 5.01 0.41 1.86e-6 Developmental language disorder (linguistic errors); TGCT cis rs4742903 0.967 rs10512325 chr9:106861191 C/T cg21169611 chr9:106856078 SMC2 0.49 4.6 0.38 1.03e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs7267979 0.966 rs2257705 chr20:25264664 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3749237 0.595 rs11130196 chr3:49490149 A/C cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs1395 0.925 rs1275541 chr2:27389195 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.51 -6.73 -0.52 5.72e-10 Blood metabolite levels; TGCT cis rs7219021 0.705 rs67174000 chr17:46982380 G/A cg26022315 chr17:47021804 SNF8 -0.53 -4.73 -0.39 5.96e-6 Schizophrenia or bipolar disorder; TGCT cis rs7043114 0.507 rs2007837 chr9:95189767 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.56 -5.59 -0.45 1.39e-7 Height; TGCT cis rs981844 0.712 rs878911 chr4:154755615 A/G cg14289246 chr4:154710475 SFRP2 -0.96 -8.97 -0.63 3.91e-15 Response to statins (LDL cholesterol change); TGCT cis rs6909430 0.539 rs17058417 chr6:98795332 G/A cg20000812 chr6:99276697 NA -0.52 -4.6 -0.38 1.03e-5 Quantitative traits; TGCT cis rs9309473 0.687 rs11693531 chr2:73608614 C/G cg20560298 chr2:73613845 ALMS1 -0.45 -4.96 -0.41 2.28e-6 Metabolite levels; TGCT trans rs1814175 0.817 rs1794162 chr11:49899506 A/C cg03929089 chr4:120376271 NA -0.71 -8.06 -0.59 5.34e-13 Height; TGCT cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg16145915 chr7:1198662 ZFAND2A -0.57 -7.46 -0.56 1.34e-11 Longevity;Endometriosis; TGCT cis rs9467773 1.000 rs6456734 chr6:26566965 G/T cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs601339 0.878 rs7956284 chr12:123183017 G/A cg11919336 chr12:123188078 GPR109A 0.64 7.74 0.57 3.07e-12 Adiponectin levels; TGCT cis rs8014204 0.806 rs11159105 chr14:75298052 C/T cg06637938 chr14:75390232 RPS6KL1 0.7 6.74 0.52 5.37e-10 Caffeine consumption; TGCT cis rs12477438 0.520 rs11123766 chr2:99780915 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs4478858 0.735 rs4531329 chr1:31817810 A/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs4665809 1.000 rs7573118 chr2:26308086 A/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg03806693 chr22:41940476 POLR3H -1.12 -13.03 -0.76 5.66e-25 Vitiligo; TGCT cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg06634786 chr22:41940651 POLR3H 0.89 8.81 0.62 9.46e-15 Crohn's disease;Inflammatory bowel disease; TGCT trans rs3780486 0.846 rs7865745 chr9:33140976 A/G cg04842962 chr6:43655489 MRPS18A -1.15 -14.87 -0.8 2.43e-29 IgG glycosylation; TGCT cis rs68170813 0.605 rs74632724 chr7:107136759 A/G cg02696742 chr7:106810147 HBP1 -0.59 -4.57 -0.38 1.14e-5 Coronary artery disease; TGCT cis rs896854 0.818 rs896855 chr8:95959808 A/G cg13393036 chr8:95962371 TP53INP1 -0.63 -8.63 -0.61 2.46e-14 Type 2 diabetes; TGCT cis rs651907 0.557 rs34947019 chr3:101532235 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.43 0.68 1.13e-18 Colorectal cancer; TGCT cis rs1008375 0.931 rs10939734 chr4:17570709 C/T cg10189774 chr4:17578691 LAP3 0.67 5.87 0.47 3.77e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs8103278 1.000 rs11671524 chr19:46327166 G/A cg11657440 chr19:46296263 DMWD -0.6 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg24549020 chr5:56110836 MAP3K1 -0.7 -6.01 -0.48 1.88e-8 Initial pursuit acceleration; TGCT cis rs1577917 1.000 rs10944163 chr6:86658693 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.36 -0.43 3.86e-7 Response to antipsychotic treatment; TGCT cis rs11650494 0.908 rs77247327 chr17:47411493 T/C cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs17401966 0.540 rs1536262 chr1:10438687 C/T cg19773385 chr1:10388646 KIF1B -0.22 -5.27 -0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs7666738 0.800 rs2865987 chr4:99067852 A/C cg17366294 chr4:99064904 C4orf37 0.76 7.74 0.57 3e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.592 rs28750375 chr22:41990644 A/C cg06481639 chr22:41940642 POLR3H -0.62 -5.26 -0.43 6.21e-7 Vitiligo; TGCT cis rs56104184 0.830 rs55966626 chr19:49342396 G/T cg15549821 chr19:49342101 PLEKHA4 -0.87 -11.91 -0.73 2.81e-22 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7010267 0.596 rs4336637 chr8:120016636 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs7617773 0.780 rs35411187 chr3:48360017 C/G cg11946769 chr3:48343235 NME6 0.82 7.08 0.54 9.69e-11 Coronary artery disease; TGCT cis rs9394841 0.692 rs56215622 chr6:41892457 G/A cg08135965 chr6:41755394 TOMM6 0.58 5.2 0.42 8.14e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs921968 0.541 rs636723 chr2:219373197 A/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs59197085 0.515 rs17165121 chr7:128442479 A/G cg00260937 chr7:128520193 KCP 0.47 5.21 0.42 7.54e-7 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs9911578 0.967 rs11079368 chr17:57086473 C/T cg12560992 chr17:57184187 TRIM37 -0.79 -9.71 -0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs2282802 0.685 rs10051345 chr5:139670932 C/G cg01081189 chr5:139537190 NA -0.28 -5.08 -0.42 1.34e-6 Intelligence (multi-trait analysis); TGCT cis rs77236434 0.571 rs1349960 chr8:13190377 G/T cg07307335 chr8:12602187 LONRF1 0.33 4.62 0.38 9.32e-6 Familial hepatitis B virus-related hepatocellular carcinoma; TGCT cis rs763014 0.931 rs7191939 chr16:630089 C/T cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs6733011 0.508 rs13004700 chr2:99527568 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.55 -5.19 -0.42 8.26e-7 Bipolar disorder; TGCT cis rs4951018 0.821 rs7529037 chr1:205637501 C/G cg07167872 chr1:205819463 PM20D1 -0.38 -4.6 -0.38 1.03e-5 Prostate-specific antigen levels; TGCT trans rs8073060 0.586 rs8077826 chr17:34001139 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs11148252 0.532 rs9536185 chr13:53179801 G/A cg00495681 chr13:53174319 NA 0.9 9.93 0.67 1.87e-17 Lewy body disease; TGCT cis rs7829975 0.514 rs2976929 chr8:8258712 T/C cg08975724 chr8:8085496 FLJ10661 0.56 5.01 0.41 1.82e-6 Mood instability; TGCT cis rs7824557 0.872 rs1347410 chr8:11111242 G/A cg21775007 chr8:11205619 TDH -0.49 -4.71 -0.39 6.43e-6 Retinal vascular caliber; TGCT cis rs7681440 0.874 rs1442154 chr4:90775761 C/G cg26578617 chr4:90757533 SNCA -0.44 -4.54 -0.38 1.31e-5 Dementia with Lewy bodies; TGCT cis rs56104184 0.690 rs56312501 chr19:49395933 T/C cg17863274 chr19:49399704 TULP2 -0.31 -4.54 -0.38 1.33e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs610932 0.517 rs678384 chr11:60002192 T/G cg18570331 chr11:60101691 MS4A6E 0.5 4.45 0.37 1.89e-5 Alzheimer's disease; TGCT cis rs78456975 1.000 rs13413096 chr2:1553588 G/A cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9443645 0.901 rs9448590 chr6:79606429 C/G cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg04389838 chr3:44770851 ZNF501 -0.37 -4.76 -0.39 5.23e-6 Depressive symptoms; TGCT trans rs3780486 1.000 rs10813957 chr9:33153527 G/T cg20290983 chr6:43655470 MRPS18A 1.22 10.5 0.69 7.76e-19 IgG glycosylation; TGCT cis rs112591243 1.000 rs112591243 chr21:47718796 G/A cg10657630 chr21:48055338 PRMT2 1.06 5.76 0.46 6.31e-8 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9399135 0.967 rs9389253 chr6:135329755 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs651907 0.535 rs17347156 chr3:101504674 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.5 4.61 0.38 1.01e-5 Colorectal cancer; TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg27535305 chr1:53392650 SCP2 -0.23 -4.53 -0.38 1.38e-5 Monocyte count; TGCT cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg03452623 chr4:187889614 NA 0.36 5.26 0.43 6.19e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs916888 0.821 rs199512 chr17:44857352 T/C cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs687432 0.774 rs12805812 chr11:57910378 G/A cg04811534 chr11:57115016 P2RX3 0.18 4.48 0.37 1.66e-5 Parkinson's disease; TGCT cis rs7572733 0.555 rs6729473 chr2:198763928 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.11 0.42 1.21e-6 Dermatomyositis; TGCT cis rs9914544 0.762 rs4322727 chr17:18798573 A/T cg26378065 chr17:18585709 ZNF286B -0.53 -4.97 -0.41 2.19e-6 Educational attainment (years of education); TGCT cis rs77372450 0.551 rs10866685 chr5:157104711 G/A cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.51e-6 Bipolar disorder (body mass index interaction); TGCT cis rs981844 0.775 rs17371274 chr4:154738713 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.79 0.62 1.03e-14 Response to statins (LDL cholesterol change); TGCT trans rs7819412 0.838 rs4840544 chr8:10960572 C/T cg15556689 chr8:8085844 FLJ10661 -0.79 -7.7 -0.57 3.72e-12 Triglycerides; TGCT cis rs2657888 0.965 rs2657902 chr12:56933651 G/A cg23932658 chr12:57637574 STAC3 0.48 4.57 0.38 1.18e-5 Adiponectin levels; TGCT cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg15691649 chr6:25882328 NA -0.56 -7.3 -0.55 3.04e-11 Urate levels; TGCT cis rs9400467 0.506 rs12207199 chr6:111525906 G/A cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs2153535 0.580 rs7761937 chr6:8459434 A/T cg07606381 chr6:8435919 SLC35B3 0.57 5.26 0.43 6.05e-7 Motion sickness; TGCT cis rs6831352 0.879 rs7672728 chr4:100055173 A/G cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.91 0.4 2.84e-6 Prudent dietary pattern; TGCT trans rs77457752 0.525 rs10120720 chr9:13897929 G/C cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.21e-10 Breast cancer; TGCT cis rs317689 0.876 rs547332 chr12:69743639 C/G cg14784868 chr12:69753453 YEATS4 0.55 4.69 0.39 7.18e-6 Response to diuretic therapy; TGCT cis rs78545713 1.000 rs41266821 chr6:26247198 A/G cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.72 -4.67 -0.39 7.66e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs12142240 0.628 rs56126529 chr1:46808860 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs2050392 1.000 rs7077496 chr10:30692028 G/A cg13289132 chr10:30722225 MAP3K8 0.36 4.58 0.38 1.13e-5 Inflammatory bowel disease; TGCT cis rs6424115 1.000 rs35385477 chr1:24155924 G/A cg15997130 chr1:24165203 NA 0.89 9.78 0.66 4.4e-17 Immature fraction of reticulocytes; TGCT cis rs9486715 0.964 rs6921480 chr6:97066329 C/G cg06623918 chr6:96969491 KIAA0776 -1.08 -13.52 -0.77 3.67e-26 Headache; TGCT cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Vitiligo; TGCT cis rs892864 0.614 rs10057855 chr5:127676365 A/G cg01939274 chr5:127874478 FBN2 -0.95 -4.56 -0.38 1.21e-5 Multiple system atrophy; TGCT cis rs1008375 0.966 rs6832962 chr4:17652133 T/C cg18681998 chr4:17616180 MED28 0.96 10.38 0.68 1.51e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7542091 0.704 rs1108628 chr1:210041150 A/G cg21951975 chr1:209979733 IRF6 0.61 6.19 0.49 8.21e-9 Monobrow; TGCT cis rs137699 0.959 rs5757633 chr22:39756270 A/G cg11247378 chr22:39784982 NA -0.46 -4.99 -0.41 2.03e-6 IgG glycosylation; TGCT cis rs4927850 0.529 rs6800500 chr3:195833507 T/C cg06252355 chr3:195477915 MUC4 -0.2 -4.53 -0.38 1.34e-5 Pancreatic cancer; TGCT cis rs7829975 0.501 rs2980769 chr8:8320291 G/A cg15556689 chr8:8085844 FLJ10661 0.7 6.37 0.5 3.43e-9 Mood instability; TGCT cis rs6089584 0.893 rs6089305 chr20:60571817 T/C cg06108461 chr20:60628389 TAF4 -0.59 -8.38 -0.6 9.49e-14 Body mass index; TGCT cis rs9926296 0.609 rs4785709 chr16:89796665 G/A cg26513180 chr16:89883248 FANCA -0.69 -6.67 -0.51 7.61e-10 Vitiligo; TGCT cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg20607798 chr8:58055168 NA 0.45 4.61 0.38 9.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs11711311 1.000 rs7649590 chr3:113447267 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.71 -6.58 -0.51 1.19e-9 IgG glycosylation; TGCT cis rs1421811 0.606 rs10057069 chr5:32716589 A/G cg16267343 chr5:32710456 NPR3 0.76 6.44 0.5 2.32e-9 Blood pressure; TGCT cis rs6785206 0.614 rs61292315 chr3:128542609 C/T cg25356066 chr3:128598488 ACAD9 -0.93 -4.8 -0.4 4.53e-6 Lymphocyte percentage of white cells; TGCT cis rs10782582 0.609 rs1796810 chr1:76403305 C/T cg10523679 chr1:76189770 ACADM -0.57 -5.14 -0.42 1.04e-6 Daytime sleep phenotypes; TGCT cis rs7666738 0.830 rs3907020 chr4:99038583 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs853679 0.546 rs34295134 chr6:27828151 T/A cg08798685 chr6:27730294 NA -0.34 -4.69 -0.39 7.2e-6 Depression; TGCT cis rs8180040 0.934 rs4858811 chr3:47480524 G/C cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs2228479 0.717 rs1800358 chr16:89809319 T/C cg27121462 chr16:89883253 FANCA 0.77 4.61 0.38 9.93e-6 Skin colour saturation; TGCT cis rs1008375 1.000 rs10012335 chr4:17628630 C/G cg18681998 chr4:17616180 MED28 1.02 11.4 0.72 4.89e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9921192 1.000 rs233950 chr16:4327397 A/G cg00021532 chr16:4324280 TFAP4 0.83 9.34 0.64 4.86e-16 Prostate-specific antigen levels; TGCT cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg18305652 chr10:134549665 INPP5A 0.35 5.55 0.45 1.66e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17102423 0.594 rs942628 chr14:65539463 C/G cg11161011 chr14:65562177 MAX -0.45 -6.33 -0.49 4.07e-9 Obesity-related traits; TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg22166914 chr1:53195759 ZYG11B 0.37 5.81 0.46 4.92e-8 Monocyte count; TGCT cis rs9549367 0.636 rs486407 chr13:113833499 G/A cg18105134 chr13:113819100 PROZ 0.47 8.56 0.61 3.67e-14 Platelet distribution width; TGCT cis rs6882046 0.513 rs618298 chr5:88038390 A/G cg22951263 chr5:87985283 NA -0.56 -5.82 -0.46 4.73e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs6433857 0.536 rs12464424 chr2:181349137 A/G cg23363182 chr2:181467187 NA -0.32 -4.85 -0.4 3.56e-6 Body mass index; TGCT cis rs6750795 0.502 rs11685196 chr2:232381298 A/G cg19187155 chr2:232395269 NMUR1 0.45 5.15 0.42 1.02e-6 Height; TGCT cis rs7267979 1.000 rs12428 chr20:25433821 G/T cg03522245 chr20:25566470 NINL -0.56 -6.04 -0.48 1.69e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6459680 0.516 rs1534008 chr7:156259583 C/T cg02321112 chr7:156810523 NA -0.38 -4.64 -0.38 8.89e-6 Glomerular filtration rate (creatinine); TGCT cis rs7103648 0.695 rs6485758 chr11:47530024 G/A cg20307385 chr11:47447363 PSMC3 0.87 8.49 0.61 5.4e-14 Diastolic blood pressure;Systolic blood pressure; TGCT trans rs2288327 0.557 rs7588593 chr2:179352450 T/C cg14011486 chr1:26737247 LIN28 1.03 7.28 0.55 3.41e-11 Atrial fibrillation; TGCT cis rs7666738 0.830 rs11944035 chr4:98931618 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 1.000 rs2371186 chr3:40488713 G/C cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs910316 0.663 rs175034 chr14:75463687 T/G cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.37e-7 Height; TGCT cis rs1801251 0.896 rs921054 chr2:233694673 G/A cg25237894 chr2:233734115 C2orf82 -0.27 -5.01 -0.41 1.83e-6 Coronary artery disease; TGCT cis rs12477438 0.798 rs1453562 chr2:99615850 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs1505368 0.534 rs10185241 chr2:213244124 C/T cg16329650 chr2:213403929 ERBB4 0.59 5.18 0.42 8.57e-7 Symmetrical dimethylarginine levels; TGCT cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg06238570 chr21:40685208 BRWD1 0.68 6.36 0.5 3.5e-9 Cognitive function; TGCT cis rs10949834 0.824 rs3801461 chr7:73536368 C/G cg07137043 chr7:73588983 EIF4H -0.74 -4.53 -0.38 1.38e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs7819412 0.511 rs7464263 chr8:11434176 A/T cg21775007 chr8:11205619 TDH -0.54 -5.07 -0.41 1.41e-6 Triglycerides; TGCT cis rs1008375 0.966 rs7658240 chr4:17588950 A/G cg18681998 chr4:17616180 MED28 -0.86 -8.25 -0.6 1.93e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6831352 0.918 rs7670241 chr4:100059619 G/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs4242434 0.757 rs7005025 chr8:22519815 G/T cg21658235 chr8:22456391 C8orf58 0.43 4.56 0.38 1.22e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs453301 0.624 rs4841083 chr8:8870428 A/G cg15556689 chr8:8085844 FLJ10661 0.76 6.59 0.51 1.13e-9 Joint mobility (Beighton score); TGCT cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg14983838 chr19:29218262 NA 0.83 6.85 0.52 3.07e-10 Methadone dose in opioid dependence; TGCT cis rs4924935 1.000 rs6502674 chr17:18776897 A/G cg26378065 chr17:18585709 ZNF286B 0.6 5.18 0.42 8.82e-7 Pancreatic cancer; TGCT cis rs9467711 1.000 rs6908156 chr6:26322861 C/T cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1552244 0.515 rs6768768 chr3:10177653 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.34 -4.9 -0.4 2.93e-6 Alzheimer's disease; TGCT cis rs921968 0.608 rs11678428 chr2:219352598 C/T cg02176678 chr2:219576539 TTLL4 0.39 5.66 0.45 1e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg22963979 chr7:1858916 MAD1L1 0.44 7.19 0.54 5.26e-11 Bipolar disorder and schizophrenia; TGCT cis rs57590327 0.679 rs1907880 chr3:81567861 C/T cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs637571 0.544 rs56239996 chr11:65730003 A/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.63 6.33 0.49 4.02e-9 Eosinophil percentage of white cells; TGCT cis rs6964587 0.967 rs7786031 chr7:91649001 T/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg01448562 chr3:133502909 NA -0.26 -4.9 -0.4 2.98e-6 Iron status biomarkers; TGCT cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg06634786 chr22:41940651 POLR3H -0.88 -8.23 -0.59 2.17e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2836633 0.965 rs2836615 chr21:40048039 C/T cg05519781 chr21:40033154 ERG 0.68 6.76 0.52 4.7e-10 Coronary artery disease; TGCT cis rs9467773 1.000 rs10946834 chr6:26533664 G/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs2758596 0.850 rs2842879 chr1:156163695 G/T cg24450063 chr1:156163899 SLC25A44 0.79 4.58 0.38 1.11e-5 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs7552404 1.000 rs211718 chr1:76106675 C/T cg03433033 chr1:76189801 ACADM 0.83 9.8 0.66 3.81e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2637266 0.967 rs6480826 chr10:78356154 A/G cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs79387448 0.701 rs3752659 chr2:103001598 A/G cg09003973 chr2:102972529 NA 1.19 9.18 0.64 1.2e-15 Gut microbiota (bacterial taxa); TGCT cis rs2242116 0.796 rs7645278 chr3:46974100 A/C cg23352942 chr3:46931381 PTH1R -0.31 -4.51 -0.38 1.5e-5 Birth weight; TGCT cis rs13242816 1.000 rs62468978 chr7:116127099 A/G cg16553024 chr7:116138462 CAV2 -0.43 -4.88 -0.4 3.26e-6 P wave duration; TGCT cis rs3796352 0.667 rs9831977 chr3:52854140 T/G cg15956490 chr3:53032818 SFMBT1 0.57 5.02 0.41 1.79e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg16405210 chr4:1374714 KIAA1530 0.25 4.62 0.38 9.42e-6 Longevity; TGCT cis rs4851266 1.000 rs4303732 chr2:100830040 T/C cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs1568889 0.838 rs11030220 chr11:28145769 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.24 0.71 1.22e-20 Bipolar disorder; TGCT cis rs9788721 0.836 rs2656052 chr15:78740932 A/C cg18825076 chr15:78729989 IREB2 -0.33 -5.32 -0.43 4.68e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs611744 0.967 rs681099 chr8:109218892 T/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs10186029 0.616 rs12616255 chr2:213978895 T/A cg08319019 chr2:214017104 IKZF2 0.62 5.73 0.46 7.14e-8 Systemic sclerosis; TGCT cis rs6570726 0.935 rs411641 chr6:145827532 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.57 -5.48 -0.44 2.29e-7 Prudent dietary pattern; TGCT cis rs6931421 0.800 rs12662365 chr6:80905389 T/A cg08355045 chr6:80787529 NA 0.3 4.82 0.4 4.14e-6 Sitting height ratio; TGCT cis rs7586879 0.828 rs4077677 chr2:25122798 G/C cg01884057 chr2:25150051 NA 0.27 4.81 0.4 4.36e-6 Body mass index; TGCT cis rs7100689 0.646 rs6585946 chr10:82118292 G/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs11785400 0.793 rs2280879 chr8:143722228 T/C cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.7e-7 Schizophrenia; TGCT cis rs7937682 0.711 rs4938792 chr11:111420936 T/C cg09085632 chr11:111637200 PPP2R1B 0.79 8.0 0.58 7.49e-13 Primary sclerosing cholangitis; TGCT cis rs2228479 0.850 rs1800344 chr16:89816367 T/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs1577917 1.000 rs955196 chr6:86729951 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 4.93 0.4 2.57e-6 Response to antipsychotic treatment; TGCT cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg22920501 chr2:26401640 FAM59B -0.79 -6.35 -0.5 3.68e-9 Gut microbiome composition (summer); TGCT cis rs12681287 0.577 rs13257414 chr8:87494138 C/T cg27223183 chr8:87520930 FAM82B -0.92 -6.79 -0.52 4.12e-10 Caudate activity during reward; TGCT cis rs981844 0.775 rs72733610 chr4:154732336 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.88 0.62 6.23e-15 Response to statins (LDL cholesterol change); TGCT trans rs4919669 0.546 rs2145307 chr10:104280664 G/A cg19053889 chr7:1098703 C7orf50;GPR146 0.51 6.73 0.52 5.65e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs2191566 0.922 rs7245749 chr19:44513932 G/A cg03039196 chr19:44506973 ZNF230 0.53 4.47 0.37 1.73e-5 Acute lymphoblastic leukemia (childhood); TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg00634968 chr6:51707133 PKHD1 0.71 6.73 0.52 5.72e-10 Gambling; TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs3087591 0.879 rs12103564 chr17:29607243 A/T cg24425628 chr17:29625626 OMG;NF1 -0.45 -6.52 -0.51 1.62e-9 Hip circumference; TGCT cis rs78487399 0.831 rs17031142 chr2:43847646 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.68 4.59 0.38 1.08e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs8103278 0.507 rs522769 chr19:46284520 G/A cg11657440 chr19:46296263 DMWD 0.78 8.46 0.61 6.22e-14 Coronary artery disease; TGCT cis rs9814567 0.806 rs9857995 chr3:134316706 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.76 7.1 0.54 8.54e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11098499 0.820 rs28578366 chr4:120536905 A/G cg09307838 chr4:120376055 NA -0.68 -6.51 -0.5 1.69e-9 Corneal astigmatism; TGCT cis rs2063714 0.967 rs1012534 chr6:157209663 A/G cg23222435 chr6:157204239 ARID1B -0.3 -5.0 -0.41 1.93e-6 Sitting height ratio; TGCT cis rs950169 0.922 rs11639244 chr15:84832650 G/A cg11189052 chr15:85197271 WDR73 0.81 6.52 0.51 1.61e-9 Schizophrenia; TGCT cis rs6667605 0.527 rs4422947 chr1:2539590 C/T cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs587847 0.708 rs4924150 chr15:37633302 T/C cg00216138 chr15:37171175 LOC145845 0.32 4.74 0.39 5.71e-6 Intraocular pressure; TGCT cis rs7666738 0.830 rs17027102 chr4:98919221 A/G cg18180107 chr4:99064573 C4orf37 -0.57 -5.19 -0.42 8.25e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs13144564 chr4:98939276 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.720 rs412623 chr6:145883257 C/A cg05347473 chr6:146136440 FBXO30 0.53 4.87 0.4 3.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7211079 0.879 rs72852522 chr17:78131490 C/T cg09238746 chr17:78121135 EIF4A3 -0.72 -5.83 -0.46 4.5e-8 Myocardial infarction; TGCT cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.05 0.48 1.59e-8 Alzheimer's disease; TGCT cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg03806693 chr22:41940476 POLR3H -1.16 -13.37 -0.77 8.59e-26 Vitiligo; TGCT cis rs2486288 0.656 rs11637920 chr15:45550905 T/C cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs10744422 0.764 rs4759391 chr12:123297718 T/A cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs56150431 chr4:119764786 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg15242686 chr22:24348715 GSTTP1 -0.53 -6.39 -0.5 3.06e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.68 -7.04 -0.53 1.15e-10 Intelligence (multi-trait analysis); TGCT cis rs4727027 0.866 rs2373437 chr7:148779032 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.99 0.41 2.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2115630 0.805 rs8042926 chr15:85205454 T/A cg12501888 chr15:85177176 SCAND2 -0.46 -4.46 -0.37 1.83e-5 P wave terminal force; TGCT cis rs4892230 1 rs4892230 chr18:72155572 G/A cg26446133 chr18:72167187 CNDP2 -0.26 -4.66 -0.39 8.07e-6 Mononucleosis; TGCT cis rs61990749 0.597 rs7142390 chr14:78232880 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.48 0.37 1.7e-5 Fibroblast growth factor basic levels; TGCT cis rs10484885 0.690 rs292236 chr6:90528422 A/G cg13799429 chr6:90582589 CASP8AP2 -0.49 -5.17 -0.42 8.96e-7 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7447593 0.626 rs3812036 chr5:176813404 C/T cg16006841 chr5:176797999 RGS14 0.6 8.33 0.6 1.24e-13 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11118844 0.793 rs7516292 chr1:221942413 C/T cg04222084 chr1:221915650 DUSP10 -0.79 -5.51 -0.44 2.01e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs7681440 0.647 rs6814221 chr4:90805501 C/T cg10208370 chr4:90758469 SNCA -0.56 -5.27 -0.43 5.93e-7 Dementia with Lewy bodies; TGCT cis rs3110496 1.000 rs3110496 chr17:27917771 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.59 4.58 0.38 1.11e-5 Height; TGCT cis rs4455778 0.580 rs4467894 chr7:49116541 G/T cg26309511 chr7:48887640 NA -0.51 -6.64 -0.51 8.83e-10 Lung cancer in never smokers; TGCT cis rs151997 0.720 rs152096 chr5:50213850 A/G cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs10832963 1.000 rs10832963 chr11:18664241 T/G cg09201001 chr11:18656081 SPTY2D1 1.03 11.49 0.72 2.92e-21 Breast cancer; TGCT cis rs911555 0.755 rs10144051 chr14:103885931 A/C cg23461800 chr14:103021989 NA 0.33 4.46 0.37 1.83e-5 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs8070740 0.838 rs35491297 chr17:5327481 T/G cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.55 0.38 1.27e-5 Menopause (age at onset); TGCT cis rs4455778 0.580 rs4270913 chr7:49112389 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.9e-9 Lung cancer in never smokers; TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg06873352 chr17:61820015 STRADA 0.58 6.48 0.5 1.93e-9 Prudent dietary pattern; TGCT cis rs2455799 0.613 rs11712323 chr3:15891360 T/C cg16303742 chr3:15540471 COLQ -0.25 -4.68 -0.39 7.4e-6 Mean platelet volume; TGCT cis rs2456568 0.802 rs10765639 chr11:93636194 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.07e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs13223928 0.541 rs66883350 chr7:3136548 T/A cg19214707 chr7:3157722 NA -0.4 -5.29 -0.43 5.27e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs7772486 0.902 rs2748500 chr6:146314852 C/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 9.88e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs2455799 0.634 rs11128764 chr3:15902836 G/C cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.68e-6 Mean platelet volume; TGCT cis rs35306767 0.714 rs12777800 chr10:1070361 G/A cg18964960 chr10:1102726 WDR37 0.69 4.9 0.4 2.99e-6 Eosinophil percentage of granulocytes; TGCT cis rs12210905 0.688 rs12189640 chr6:27474657 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs6988636 1.000 rs57165742 chr8:124184559 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9487051 0.604 rs9320282 chr6:109619377 A/G cg01475377 chr6:109611718 NA -0.29 -4.52 -0.38 1.4e-5 Reticulocyte fraction of red cells; TGCT cis rs7584330 0.910 rs66509917 chr2:238395394 T/G cg14458575 chr2:238380390 NA 0.42 6.42 0.5 2.57e-9 Prostate cancer; TGCT cis rs1218582 0.774 rs1007170 chr1:154881461 G/A cg24250549 chr1:154909240 PMVK 0.56 5.42 0.44 2.92e-7 Prostate cancer; TGCT cis rs12142240 0.698 rs7525309 chr1:46809025 G/T cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs4824093 0.610 rs73443906 chr22:50274293 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -6.79 -0.52 4.13e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2230307 0.536 rs6577152 chr1:100434610 A/G cg24955406 chr1:100503596 HIAT1 0.72 4.64 0.38 8.82e-6 Carotid intima media thickness; TGCT cis rs73110464 0.609 rs11170348 chr12:53355588 A/G cg05393297 chr12:53359155 NA -0.79 -8.43 -0.6 7.2e-14 Cancer (pleiotropy); TGCT cis rs10832963 0.924 rs10832950 chr11:18635815 A/G cg20219074 chr11:18656078 SPTY2D1 1.0 9.93 0.67 1.85e-17 Breast cancer; TGCT cis rs9583531 0.689 rs1061386 chr13:111373368 G/C cg24331049 chr13:111365604 ING1 0.82 7.16 0.54 6.19e-11 Coronary artery disease; TGCT cis rs13242816 1.000 rs2024209 chr7:116135336 T/C cg16553024 chr7:116138462 CAV2 -0.45 -5.06 -0.41 1.49e-6 P wave duration; TGCT cis rs1218582 0.772 rs2061690 chr1:154919080 C/T cg06221963 chr1:154839813 KCNN3 -0.73 -12.51 -0.75 1.01e-23 Prostate cancer; TGCT cis rs9902453 0.817 rs7217961 chr17:28403112 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.82 -7.84 -0.58 1.8e-12 Coffee consumption (cups per day); TGCT cis rs2456568 0.778 rs7940973 chr11:93682045 C/G cg14065697 chr11:93583672 C11orf90 0.37 4.56 0.38 1.22e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs7552167 0.852 rs10794647 chr1:24509133 C/T cg01960748 chr1:24522592 NA -0.49 -5.47 -0.44 2.38e-7 Psoriasis vulgaris; TGCT cis rs6582630 0.555 rs10880624 chr12:38526316 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.78 0.57 2.47e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs2549003 1.000 rs13170412 chr5:131823519 A/G cg21138405 chr5:131827807 IRF1 0.18 4.49 0.37 1.63e-5 Asthma (sex interaction); TGCT trans rs7726839 0.574 rs72705017 chr5:623733 G/A cg25482853 chr8:67687455 SGK3 1.23 9.86 0.66 2.81e-17 Obesity-related traits; TGCT cis rs2956278 0.717 rs2956290 chr12:84682272 A/C cg25678815 chr12:85673915 ALX1 -0.54 -4.86 -0.4 3.48e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs9419702 0.639 rs9419624 chr10:133534822 G/A cg04492858 chr10:133558786 NA 0.53 5.74 0.46 6.85e-8 Survival in rectal cancer; TGCT cis rs2729354 0.817 rs2848626 chr11:57283988 C/T cg24343310 chr11:57249947 NA 0.3 5.01 0.41 1.85e-6 Blood protein levels; TGCT cis rs1185460 0.967 rs1177563 chr11:118949083 C/T cg01677386 chr11:118938358 VPS11 -0.55 -4.74 -0.39 5.83e-6 Coronary artery disease; TGCT trans rs17471911 0.581 rs10883245 chr10:100760306 A/T cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs57244997 1.000 rs57244997 chr6:162397506 G/A cg17173639 chr6:162384350 PARK2 -0.52 -5.43 -0.44 2.85e-7 Mosquito bite size; TGCT trans rs17685 0.753 rs6464999 chr7:75787315 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2204008 0.902 rs11520218 chr12:38223227 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.38 0.55 2e-11 Bladder cancer; TGCT cis rs6582630 0.519 rs8189618 chr12:38276281 A/C cg13010199 chr12:38710504 ALG10B 0.61 4.67 0.39 7.69e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1903068 1.000 rs1903068 chr4:56008477 A/G cg01777861 chr4:56023843 NA 0.55 6.49 0.5 1.86e-9 Endometriosis; TGCT cis rs7208859 0.573 rs79505916 chr17:29062326 C/T cg13385521 chr17:29058706 SUZ12P 0.79 4.78 0.39 4.82e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9372253 1.000 rs2235989 chr6:110714584 A/T cg00083206 chr6:110721305 DDO -0.41 -6.25 -0.49 5.94e-9 Platelet distribution width; TGCT cis rs2295359 1.000 rs11465754 chr1:67631431 A/G cg12940439 chr1:67600707 NA 0.54 5.78 0.46 5.78e-8 Psoriasis; TGCT cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg18230493 chr5:56204884 C5orf35 -0.67 -5.88 -0.47 3.5e-8 Initial pursuit acceleration; TGCT cis rs2455799 0.573 rs2654648 chr3:15775425 T/C cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs11785400 0.793 rs4736364 chr8:143742113 C/T cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs796364 1.000 rs166845 chr2:200823360 T/A cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs2120019 0.638 rs12050628 chr15:75333494 G/A cg17294928 chr15:75287854 SCAMP5 0.93 8.84 0.62 8.02e-15 Blood trace element (Zn levels); TGCT cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs3754214 0.823 rs10888579 chr1:150261925 C/T cg09579323 chr1:150459698 TARS2 -0.53 -4.81 -0.4 4.38e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7726839 0.540 rs4957080 chr5:644552 A/C cg09021430 chr5:549028 NA 0.39 5.37 0.43 3.77e-7 Obesity-related traits; TGCT trans rs208520 0.526 rs9354370 chr6:66808209 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.08 16.81 0.83 9.08e-34 Exhaled nitric oxide output; TGCT cis rs926938 0.505 rs360593 chr1:115472265 T/G cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs3008870 0.583 rs2031495 chr1:67421714 G/T cg11518657 chr1:67396239 MIER1 0.6 4.76 0.39 5.32e-6 Lymphocyte percentage of white cells; TGCT cis rs933688 1.000 rs12656350 chr5:90751343 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.95 8.12 0.59 3.93e-13 Smoking behavior; TGCT cis rs8016982 0.698 rs8021385 chr14:81704682 G/A cg01989461 chr14:81687754 GTF2A1 0.77 7.16 0.54 6.37e-11 Schizophrenia; TGCT cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg25767906 chr1:53392781 SCP2 0.46 5.11 0.42 1.19e-6 Monocyte count; TGCT cis rs7208859 0.623 rs11650271 chr17:29213943 C/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs61990749 0.597 rs1008988 chr14:78260795 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs13242816 1.000 rs2024209 chr7:116135336 T/C cg02799643 chr7:116139180 CAV2 -0.46 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs10751667 0.666 rs7395321 chr11:940280 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs611744 0.967 rs636399 chr8:109235569 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs5750830 0.649 rs5750815 chr22:39798449 T/C cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs6665290 0.935 rs17528667 chr1:227201770 C/T cg10327440 chr1:227177885 CDC42BPA -1.0 -20.66 -0.88 5.7e-42 Myeloid white cell count; TGCT cis rs9303401 0.614 rs8081058 chr17:57160513 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs3099143 1.000 rs4243043 chr15:77178540 A/G cg21673338 chr15:77095150 SCAPER 0.52 5.05 0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs4345303 0.962 rs7702760 chr5:78739087 A/C cg16405876 chr5:78317871 DMGDH 0.57 4.52 0.38 1.43e-5 Interleukin-10 levels; TGCT cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg17554472 chr22:41940697 POLR3H 0.42 4.64 0.38 8.64e-6 Vitiligo; TGCT cis rs7020830 0.894 rs28766572 chr9:37093872 G/T cg14294708 chr9:37120828 ZCCHC7 1.19 18.22 0.85 7.36e-37 Schizophrenia; TGCT cis rs11640734 0.609 rs11647746 chr16:89806343 C/A cg04287289 chr16:89883240 FANCA 0.74 4.47 0.37 1.75e-5 Interleukin-17 levels; TGCT cis rs7666738 0.830 rs7697315 chr4:98938764 T/C cg18180107 chr4:99064573 C4orf37 0.55 4.98 0.41 2.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1514658 0.903 rs1113677 chr4:119280513 T/C cg21605333 chr4:119757512 SEC24D -0.51 -4.52 -0.38 1.43e-5 Congenital heart disease (maternal effect); TGCT cis rs1670533 0.932 rs10902753 chr4:1056223 G/A cg27284194 chr4:1044797 NA 0.68 5.88 0.47 3.56e-8 Recombination rate (females); TGCT cis rs875971 0.862 rs6962717 chr7:65883735 G/A cg11764359 chr7:65958608 NA 0.57 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs10114408 0.918 rs7035672 chr9:96668153 C/G cg13679303 chr9:96623674 NA -0.36 -4.55 -0.38 1.25e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2777491 0.957 rs8027626 chr15:41711514 T/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.01 -0.7 4.47e-20 Ulcerative colitis; TGCT cis rs7043114 0.525 rs10761153 chr9:95130769 A/G cg14631576 chr9:95140430 CENPP -0.28 -4.69 -0.39 6.98e-6 Height; TGCT cis rs4689388 0.926 rs4234730 chr4:6296343 A/G cg00701064 chr4:6280414 WFS1 0.38 4.78 0.39 4.96e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12497850 0.765 rs12487580 chr3:49182932 G/A cg16497277 chr3:49208875 KLHDC8B -0.49 -4.47 -0.37 1.72e-5 Parkinson's disease; TGCT cis rs10504229 0.610 rs6999661 chr8:58127391 C/G cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs1799949 0.965 rs2236762 chr17:41226675 A/T cg05368731 chr17:41323189 NBR1 1.06 11.69 0.72 9.65e-22 Menopause (age at onset); TGCT trans rs117132860 0.661 rs62444471 chr7:17100425 T/A cg25519926 chr7:130132360 MEST;MESTIT1 0.95 6.9 0.53 2.32e-10 Cutaneous squamous cell carcinoma; TGCT cis rs6964587 0.967 rs12535601 chr7:91718346 A/G cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs11190604 0.767 rs7916904 chr10:102186778 C/G cg16342193 chr10:102329863 NA -0.38 -5.0 -0.41 1.93e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg03806693 chr22:41940476 POLR3H -0.99 -11.08 -0.71 2.91e-20 Vitiligo; TGCT cis rs114540395 0.925 rs115878498 chr10:103447267 G/A cg18276125 chr10:102749041 C10orf2 0.39 4.88 0.4 3.14e-6 Schizophrenia; TGCT cis rs853679 0.517 rs3173443 chr6:28137027 T/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs57920188 0.535 rs4520388 chr1:4092671 T/G cg20703997 chr1:4087676 NA 0.48 5.7 0.46 8.27e-8 Interleukin-17 levels; TGCT trans rs877282 0.733 rs7092976 chr10:756358 G/A cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg11301795 chr4:187892539 NA -0.33 -5.06 -0.41 1.5e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7098414 0.511 rs7071752 chr10:82159539 C/A cg00277334 chr10:82204260 NA -0.38 -4.98 -0.41 2.11e-6 Post bronchodilator FEV1; TGCT cis rs7225537 0.559 rs3744137 chr17:17046024 C/A cg26176665 chr17:16994978 MPRIP 0.25 5.87 0.47 3.65e-8 Mean platelet volume; TGCT cis rs941873 0.868 rs1483733 chr10:81130036 A/G cg09469691 chr10:81107165 PPIF 0.55 5.45 0.44 2.66e-7 Height; TGCT cis rs1878931 0.501 rs9635547 chr16:3416664 C/T cg22508957 chr16:3507546 NAT15 -0.39 -5.06 -0.41 1.49e-6 Body mass index (adult); TGCT cis rs17384381 1.000 rs12118950 chr1:85864519 T/C cg16011679 chr1:85725395 C1orf52 0.78 6.1 0.48 1.27e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs35883536 0.647 rs10875317 chr1:101045438 G/T cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs7474896 0.537 rs2749589 chr10:38266870 C/T cg13720705 chr10:37990370 NA -0.33 -4.5 -0.37 1.56e-5 Obesity (extreme); TGCT cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs7826238 0.601 rs2976907 chr8:8345168 C/T cg06636001 chr8:8085503 FLJ10661 0.64 5.96 0.47 2.41e-8 Systolic blood pressure; TGCT cis rs10088262 0.629 rs12541177 chr8:124800273 G/T cg02993010 chr8:124780839 FAM91A1 -0.63 -5.13 -0.42 1.08e-6 Pancreatic cancer; TGCT cis rs3138083 0.645 rs2039767 chr9:35638955 C/T cg07116010 chr9:35646325 NA 0.82 10.15 0.67 5.33e-18 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel); TGCT cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs7103648 0.742 rs34937994 chr11:47389638 C/T cg20307385 chr11:47447363 PSMC3 1.0 11.33 0.71 7.42e-21 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg06238570 chr21:40685208 BRWD1 0.7 6.45 0.5 2.3e-9 Cognitive function; TGCT cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg05785598 chr3:49045655 WDR6 0.36 4.78 0.39 4.78e-6 Menarche (age at onset); TGCT cis rs6893807 0.667 rs1477290 chr5:87988934 T/C cg24804195 chr5:87968844 LOC645323 0.71 4.84 0.4 3.71e-6 Body mass index; TGCT cis rs9915657 0.870 rs720244 chr17:70131643 G/T cg06234051 chr17:70120541 SOX9 -0.24 -4.92 -0.4 2.75e-6 Thyroid hormone levels; TGCT cis rs9549260 0.591 rs9577108 chr13:41271764 G/A cg21288729 chr13:41239152 FOXO1 0.94 9.32 0.64 5.56e-16 Red blood cell count; TGCT cis rs875971 1.000 rs7783613 chr7:65805261 C/T cg18876405 chr7:65276391 NA -0.32 -4.93 -0.4 2.63e-6 Aortic root size; TGCT cis rs950169 0.656 rs11632395 chr15:85145793 C/A cg12863693 chr15:85201151 NMB 0.4 4.7 0.39 6.79e-6 Schizophrenia; TGCT cis rs2688482 0.512 rs2177336 chr3:195516878 T/C cg13752114 chr3:195489708 MUC4 0.33 4.82 0.4 4.06e-6 Lung disease severity in cystic fibrosis; TGCT cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg03264133 chr6:25882463 NA -0.67 -6.04 -0.48 1.67e-8 Intelligence (multi-trait analysis); TGCT cis rs12681287 0.640 rs13282351 chr8:87484669 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.52 5.12 0.42 1.13e-6 Menarche (age at onset); TGCT cis rs2637266 0.935 rs2637265 chr10:78326104 A/G cg18941641 chr10:78392320 NA 0.42 5.38 0.43 3.6e-7 Pulmonary function; TGCT cis rs2404602 0.716 rs7169394 chr15:76913274 G/A cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.07e-6 Blood metabolite levels; TGCT cis rs7666738 0.830 rs7696715 chr4:98938486 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.547 rs377808 chr1:53190359 T/G cg22166914 chr1:53195759 ZYG11B 0.51 9.63 0.65 1.01e-16 Monocyte count; TGCT cis rs7769051 0.522 rs7759524 chr6:133109574 A/G cg07930552 chr6:133119739 C6orf192 1.28 5.03 0.41 1.69e-6 Type 2 diabetes nephropathy; TGCT cis rs6782228 1.000 rs12635488 chr3:128352378 C/T cg15113803 chr3:129247119 RHO 0.18 4.64 0.38 8.78e-6 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; TGCT cis rs9814567 1.000 rs934093 chr3:134195885 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -10.02 -0.67 1.12e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11098499 0.754 rs12513083 chr4:120249612 A/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9810089 0.706 rs521746 chr3:136103920 C/T cg12473912 chr3:136751656 NA -0.35 -4.97 -0.41 2.13e-6 Gestational age at birth (child effect); TGCT cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg03264133 chr6:25882463 NA 0.86 8.95 0.63 4.38e-15 Blood metabolite levels; TGCT cis rs9318086 0.600 rs9507185 chr13:24473734 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.82 8.98 0.63 3.58e-15 Myopia (pathological); TGCT cis rs73198271 0.628 rs74433718 chr8:8591546 A/C ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs981844 0.740 rs10024619 chr4:154684441 A/T cg14289246 chr4:154710475 SFRP2 -0.91 -8.31 -0.6 1.38e-13 Response to statins (LDL cholesterol change); TGCT cis rs2070488 0.965 rs7372849 chr3:38524328 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.89 9.01 0.63 3.09e-15 Electrocardiographic conduction measures; TGCT trans rs561341 0.714 rs55925849 chr17:30253085 C/T cg20587970 chr11:113659929 NA -1.03 -10.94 -0.7 6.67e-20 Hip circumference adjusted for BMI; TGCT cis rs2439831 0.867 rs28729853 chr15:43673680 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.86 5.95 0.47 2.53e-8 Lung cancer in ever smokers; TGCT cis rs2243480 1.000 rs419603 chr7:65597341 C/T cg07424592 chr7:64974309 NA 1.26 7.79 0.57 2.25e-12 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs644799 0.526 rs693792 chr11:95622200 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.49 5.08 0.41 1.38e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs546131 0.928 rs546521 chr11:34824773 G/C cg06937548 chr11:34938143 PDHX;APIP 0.66 6.03 0.48 1.74e-8 Lung disease severity in cystic fibrosis; TGCT cis rs2147959 0.831 rs7555386 chr1:228630589 C/G cg22700015 chr1:228743131 NA -0.57 -4.53 -0.38 1.35e-5 Adult asthma; TGCT cis rs12908161 1.000 rs11638290 chr15:85227636 C/T cg17173187 chr15:85201210 NMB 0.59 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs2456568 0.802 rs8181567 chr11:93637209 C/T cg17595323 chr11:93583763 C11orf90 -0.47 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7552404 0.727 rs12093623 chr1:76256232 T/G cg10523679 chr1:76189770 ACADM 0.74 6.98 0.53 1.61e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs611744 0.967 rs636904 chr8:109197565 T/C cg21045802 chr8:109455806 TTC35 0.5 4.5 0.37 1.53e-5 Dupuytren's disease; TGCT cis rs4273100 0.831 rs59571799 chr17:19178892 C/A cg01534423 chr17:18965556 NA 0.88 5.59 0.45 1.4e-7 Schizophrenia; TGCT cis rs7091068 0.671 rs620890 chr10:95405424 G/A cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs968451 0.865 rs5757611 chr22:39708357 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.86 8.55 0.61 3.83e-14 Primary biliary cholangitis; TGCT cis rs8141529 0.748 rs6519766 chr22:29269991 A/G cg02153584 chr22:29168773 CCDC117 -0.62 -4.77 -0.39 4.98e-6 Lymphocyte counts; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg24675658 chr1:53192096 ZYG11B 0.73 8.46 0.6 6.33e-14 Monocyte count; TGCT cis rs11264213 0.686 rs12041193 chr1:36412760 C/T cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.05 -9.12 -0.63 1.65e-15 Platelet count; TGCT cis rs12142240 0.698 rs17361887 chr1:46834775 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.63 0.45 1.12e-7 Menopause (age at onset); TGCT cis rs13242816 0.892 rs34645128 chr7:116078382 T/A cg02799643 chr7:116139180 CAV2 -0.43 -5.08 -0.42 1.33e-6 P wave duration; TGCT cis rs4746818 1.000 rs7901617 chr10:70904063 C/T cg11621586 chr10:70884670 VPS26A 1.19 10.76 0.69 1.83e-19 Left atrial antero-posterior diameter; TGCT cis rs514406 0.800 rs4926930 chr1:53217335 A/G cg24675658 chr1:53192096 ZYG11B 0.71 7.96 0.58 9.48e-13 Monocyte count; TGCT cis rs7666738 0.830 rs11097608 chr4:99011693 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.45e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.659 rs7045491 chr9:5045658 G/A cg02405213 chr9:5042618 JAK2 -0.78 -10.94 -0.7 6.34e-20 Pediatric autoimmune diseases; TGCT cis rs9291683 0.552 rs17187075 chr4:9990328 G/C cg11266682 chr4:10021025 SLC2A9 0.67 9.62 0.65 1.07e-16 Bone mineral density; TGCT cis rs910316 0.763 rs12588981 chr14:75460561 A/G cg08847533 chr14:75593920 NEK9 0.83 8.89 0.62 5.99e-15 Height; TGCT cis rs12477438 0.765 rs6749059 chr2:99591021 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.18 -0.49 8.51e-9 Chronic sinus infection; TGCT cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.86e-10 Electroencephalogram traits; TGCT trans rs1974653 0.672 rs8139107 chr22:20093288 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg22963979 chr7:1858916 MAD1L1 -0.35 -5.5 -0.44 2.05e-7 Bipolar disorder and schizophrenia; TGCT cis rs10782582 0.609 rs5745485 chr1:76349534 C/G cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs12931792 0.875 rs58175255 chr16:30155290 C/A cg17640201 chr16:30407289 ZNF48 0.65 5.8 0.46 5.29e-8 Tonsillectomy; TGCT cis rs263156 0.967 rs263155 chr6:142906405 G/A cg18419694 chr6:143832440 FUCA2 -0.4 -4.65 -0.39 8.22e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs709400 0.628 rs10141120 chr14:103923008 T/C cg26031613 chr14:104095156 KLC1 0.84 9.43 0.65 2.98e-16 Body mass index; TGCT cis rs9611519 0.929 rs71327107 chr22:41418229 T/G cg03806693 chr22:41940476 POLR3H -0.7 -6.07 -0.48 1.41e-8 Neuroticism; TGCT cis rs61897795 0.628 rs174585 chr11:61611694 G/A cg19610905 chr11:61596333 FADS2 -0.79 -6.01 -0.47 1.92e-8 Neutrophil count;Sum basophil neutrophil counts; TGCT cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg21951975 chr1:209979733 IRF6 0.69 5.92 0.47 2.98e-8 Cleft lip with or without cleft palate; TGCT cis rs7681440 0.835 rs1899389 chr4:90802998 G/A cg20003494 chr4:90757398 SNCA -0.62 -5.94 -0.47 2.7e-8 Dementia with Lewy bodies; TGCT cis rs6089584 0.888 rs6089624 chr20:60619907 C/G cg16423285 chr20:60520624 NA -0.61 -6.43 -0.5 2.45e-9 Body mass index; TGCT cis rs3733585 0.699 rs12498150 chr4:9950537 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.47 -0.56 1.25e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg18252515 chr7:66147081 NA -1.2 -7.76 -0.57 2.75e-12 Diabetic kidney disease; TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg22166914 chr1:53195759 ZYG11B 0.32 5.27 0.43 5.95e-7 Monocyte count; TGCT trans rs459571 0.959 rs461462 chr9:136911272 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.75 -8.02 -0.58 6.93e-13 Platelet distribution width; TGCT cis rs9341808 0.754 rs6916405 chr6:81024188 C/T cg08355045 chr6:80787529 NA 0.26 4.48 0.37 1.64e-5 Sitting height ratio; TGCT cis rs7772486 0.686 rs1337841 chr6:146059487 A/G cg23711669 chr6:146136114 FBXO30 -0.88 -9.9 -0.66 2.22e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs478304 0.580 rs11606947 chr11:65508237 A/C cg27068330 chr11:65405492 SIPA1 -0.95 -9.75 -0.66 4.99e-17 Acne (severe); TGCT cis rs12188164 0.965 rs1056465 chr5:442438 T/A cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs40363 0.857 rs55989968 chr16:3530658 C/G cg05754148 chr16:3507555 NAT15 0.47 4.64 0.38 8.58e-6 Tuberculosis; TGCT cis rs6570726 0.791 rs435671 chr6:145881215 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs78487399 0.808 rs6726643 chr2:43753746 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9443645 0.869 rs9361489 chr6:79816785 T/C cg09184832 chr6:79620586 NA -0.47 -5.03 -0.41 1.65e-6 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.754 rs4896832 chr6:145964151 G/A cg05347473 chr6:146136440 FBXO30 0.5 4.71 0.39 6.65e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11574514 1.000 rs10775302 chr16:67792439 C/T cg26449586 chr16:67701378 C16orf86;C16orf48 0.76 4.44 0.37 1.93e-5 Crohn's disease; TGCT cis rs34014631 1.000 rs34014631 chr10:103698705 C/T cg22630918 chr10:102748988 C10orf2 0.42 4.78 0.39 4.86e-6 Coronary artery calcification; TGCT cis rs4478037 0.556 rs55680612 chr3:33100948 C/T cg19404215 chr3:33155277 CRTAP 1.14 4.71 0.39 6.48e-6 Major depressive disorder; TGCT cis rs7523273 0.586 rs7518047 chr1:207899332 T/C cg22525895 chr1:207977042 MIR29B2 -0.33 -5.31 -0.43 4.83e-7 Schizophrenia; TGCT cis rs1670533 1.000 rs11247972 chr4:1060550 A/G cg27284194 chr4:1044797 NA 0.7 6.04 0.48 1.63e-8 Recombination rate (females); TGCT cis rs2840044 1.000 rs2840044 chr17:33892068 A/G cg05299278 chr17:33885742 SLFN14 -0.23 -5.17 -0.42 8.95e-7 Response to radiotherapy in cancer (late toxicity); TGCT cis rs1862618 0.671 rs2591968 chr5:56233541 A/G cg12311346 chr5:56204834 C5orf35 -0.56 -5.99 -0.47 2.11e-8 Initial pursuit acceleration; TGCT cis rs28493229 0.786 rs3815912 chr19:41190726 G/A cg11601297 chr19:41224147 ITPKC;ADCK4 0.54 5.24 0.43 6.57e-7 Kawasaki disease; TGCT cis rs6835098 0.962 rs6851632 chr4:174109611 A/G cg08422745 chr4:174089978 GALNT7 -0.9 -10.08 -0.67 7.91e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg17775962 chr7:1200435 ZFAND2A 0.28 4.86 0.4 3.46e-6 Longevity;Endometriosis; TGCT cis rs3008870 1.000 rs3008888 chr1:67368965 C/T cg11518657 chr1:67396239 MIER1 0.53 4.72 0.39 6.16e-6 Lymphocyte percentage of white cells; TGCT cis rs2439831 0.850 rs3862142 chr15:44064806 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs2153535 0.542 rs6905925 chr6:8440030 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs12780845 0.540 rs6602178 chr10:17180169 A/C cg01003015 chr10:17271136 VIM -0.59 -5.48 -0.44 2.32e-7 Homocysteine levels; TGCT cis rs7226408 0.901 rs72887101 chr18:34513774 G/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs12615966 1.000 rs17030292 chr2:105383596 C/G cg16465502 chr2:105461796 NA 0.78 5.03 0.41 1.66e-6 Pancreatic cancer; TGCT cis rs908922 0.676 rs525960 chr1:152497866 T/A cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.26e-9 Hair morphology; TGCT cis rs7923609 0.936 rs10822160 chr10:65112796 T/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.46 -0.37 1.78e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2012796 0.956 rs7147254 chr14:81820503 G/A cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs8044995 0.563 rs73613962 chr16:68361974 T/G cg05110241 chr16:68378359 PRMT7 -0.36 -4.45 -0.37 1.87e-5 Schizophrenia; TGCT cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Intelligence (multi-trait analysis); TGCT cis rs4073582 0.595 rs10896104 chr11:66001869 C/T cg16950941 chr11:66035639 RAB1B 0.58 5.44 0.44 2.67e-7 Gout; TGCT cis rs9534288 0.830 rs1548325 chr13:46635101 A/G cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs1059312 0.808 rs10847694 chr12:129292457 C/A cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs6860806 0.507 rs2631371 chr5:131703691 G/A cg24060327 chr5:131705240 SLC22A5 0.78 8.48 0.61 5.6e-14 Breast cancer; TGCT cis rs9583531 0.689 rs2165418 chr13:111379365 G/T cg24331049 chr13:111365604 ING1 -0.91 -9.19 -0.64 1.17e-15 Coronary artery disease; TGCT cis rs12898370 0.561 rs11630770 chr15:77469643 A/G cg27398640 chr15:77910606 LINGO1 0.34 4.53 0.38 1.35e-5 Risky sexual behaviors (alcohol dependence interaction); TGCT cis rs7809950 0.817 rs34325395 chr7:107113808 C/G cg23024343 chr7:107201750 COG5 -0.46 -6.76 -0.52 4.89e-10 Coronary artery disease; TGCT cis rs9911578 0.967 rs7214892 chr17:57065401 G/A cg05425664 chr17:57184151 TRIM37 -0.63 -6.03 -0.48 1.71e-8 Intelligence (multi-trait analysis); TGCT cis rs854765 0.663 rs3744113 chr17:17748645 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.72 -6.85 -0.52 3e-10 Total body bone mineral density; TGCT cis rs5769765 0.955 rs4075330 chr22:50303249 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.42 5.93 0.47 2.83e-8 Schizophrenia; TGCT cis rs1215050 0.791 rs260902 chr4:98764694 G/A cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7617480 0.648 rs4974083 chr3:49000626 A/G cg07636037 chr3:49044803 WDR6 0.82 6.59 0.51 1.12e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7100689 0.622 rs1340373 chr10:82129250 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs11098499 0.580 rs12509234 chr4:120319434 T/C cg09307838 chr4:120376055 NA 0.65 6.17 0.48 8.93e-9 Corneal astigmatism; TGCT cis rs986417 0.901 rs3759688 chr14:60975579 A/C cg27398547 chr14:60952738 C14orf39 1.42 8.68 0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs2797160 1.000 rs9321050 chr6:126001568 A/G cg05901451 chr6:126070800 HEY2 -0.73 -6.27 -0.49 5.51e-9 Endometrial cancer; TGCT trans rs57221529 0.766 rs72703026 chr5:572383 G/A cg25482853 chr8:67687455 SGK3 1.2 10.25 0.68 3.07e-18 Lung disease severity in cystic fibrosis; TGCT trans rs208520 1.000 rs72882102 chr6:66983408 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs1862618 0.641 rs2591954 chr5:56245044 G/C cg20203395 chr5:56204925 C5orf35 0.53 4.89 0.4 3.03e-6 Initial pursuit acceleration; TGCT cis rs12210905 0.688 rs72845008 chr6:27492961 C/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7552404 0.924 rs7544117 chr1:76158246 A/G cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9325144 0.560 rs7314632 chr12:38636979 C/T cg26384229 chr12:38710491 ALG10B -0.64 -6.09 -0.48 1.29e-8 Morning vs. evening chronotype; TGCT cis rs6750047 0.548 rs162327 chr2:38318350 G/A cg07380506 chr2:38303506 CYP1B1 0.58 5.49 0.44 2.16e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs12148488 0.763 rs2304902 chr15:75340727 G/T cg09165964 chr15:75287851 SCAMP5 0.52 4.56 0.38 1.23e-5 Caffeine consumption; TGCT cis rs597539 0.617 rs686348 chr11:68636996 A/G cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs904251 0.861 rs914349 chr6:37484715 A/C cg08126542 chr6:37504118 NA -0.42 -5.81 -0.46 5e-8 Cognitive performance; TGCT cis rs1865760 0.566 rs1971509 chr6:26085777 T/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs13256369 1.000 rs10088439 chr8:8576699 T/G cg06671706 chr8:8559999 CLDN23 0.35 4.69 0.39 6.95e-6 Obesity-related traits; TGCT cis rs7524258 0.868 rs4243825 chr1:7308264 T/C cg07173049 chr1:7289937 CAMTA1 0.28 4.6 0.38 1.04e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7044106 0.791 rs2416799 chr9:123480866 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.97 0.41 2.13e-6 Hip circumference adjusted for BMI; TGCT cis rs7010267 0.692 rs3134063 chr8:119959657 C/T cg17171407 chr8:119960777 TNFRSF11B 0.28 5.1 0.42 1.25e-6 Total body bone mineral density (age 45-60); TGCT cis rs13191362 1.000 rs13220181 chr6:163004401 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg27535305 chr1:53392650 SCP2 -0.23 -4.59 -0.38 1.06e-5 Monocyte count; TGCT cis rs7666738 0.830 rs7663438 chr4:99014582 C/T cg05340658 chr4:99064831 C4orf37 0.46 5.19 0.42 8.17e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7246657 0.722 rs2909102 chr19:38167364 C/T cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs9653442 0.564 rs4851261 chr2:100786717 A/G cg07810366 chr2:100720526 AFF3 -0.36 -5.26 -0.43 6.14e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6426558 0.524 rs2813948 chr1:227459621 A/T cg10327440 chr1:227177885 CDC42BPA 0.58 6.76 0.52 4.75e-10 Neutrophil percentage of white cells; TGCT cis rs9650657 0.538 rs11250093 chr8:10798828 C/T cg27411982 chr8:10470053 RP1L1 0.22 4.74 0.39 5.79e-6 Neuroticism; TGCT cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg24675658 chr1:53192096 ZYG11B 0.86 11.3 0.71 8.54e-21 Monocyte count; TGCT cis rs7804356 1.000 rs1327989 chr7:26833563 C/T cg03456212 chr7:26904342 SKAP2 -0.62 -4.73 -0.39 6.1e-6 Type 1 diabetes; TGCT cis rs2404618 0.593 rs7829532 chr8:1485190 C/A cg13402656 chr8:1511478 DLGAP2 -0.37 -6.0 -0.47 1.99e-8 Lung cancer; TGCT cis rs62380364 0.727 rs12054920 chr5:88161417 T/C cg22951263 chr5:87985283 NA -0.52 -5.32 -0.43 4.77e-7 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.645 rs10839448 chr11:49938930 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs1784581 0.674 rs1789996 chr6:162391895 T/C cg17173639 chr6:162384350 PARK2 -0.47 -8.16 -0.59 3.15e-13 Itch intensity from mosquito bite; TGCT cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg14500267 chr11:67383377 NA 0.32 4.98 0.41 2.04e-6 Mean corpuscular volume; TGCT cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg08048268 chr3:133502702 NA -0.54 -7.2 -0.54 5.06e-11 Iron status biomarkers; TGCT cis rs42648 0.633 rs11563909 chr7:89935704 A/G cg25739043 chr7:89950458 NA -0.62 -6.03 -0.48 1.73e-8 Homocysteine levels; TGCT cis rs4699052 0.662 rs6533083 chr4:104241267 C/T cg16532752 chr4:104119610 CENPE -0.55 -5.37 -0.43 3.75e-7 Testicular germ cell tumor; TGCT cis rs4595586 1.000 rs4595586 chr12:39225991 A/T cg10518543 chr12:38710700 ALG10B -0.46 -4.51 -0.38 1.48e-5 Morning vs. evening chronotype; TGCT cis rs67478160 0.619 rs10083370 chr14:104314182 G/A cg26031613 chr14:104095156 KLC1 0.69 6.98 0.53 1.59e-10 Schizophrenia; TGCT cis rs72615157 0.634 rs7789890 chr7:99800559 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.61 4.99 0.41 1.98e-6 Lung function (FEV1/FVC); TGCT cis rs2760061 0.603 rs697761 chr1:228192397 G/A cg18477163 chr1:228402036 OBSCN 0.36 7.17 0.54 5.84e-11 Diastolic blood pressure; TGCT cis rs7178572 0.568 rs4243045 chr15:77455914 A/C cg15453836 chr15:77711506 NA -0.45 -4.99 -0.41 2.02e-6 Type 2 diabetes; TGCT cis rs72949976 0.934 rs1441172 chr2:214037703 C/T cg08319019 chr2:214017104 IKZF2 -0.69 -6.01 -0.48 1.9e-8 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs7746199 0.668 rs34864796 chr6:27459923 G/A cg10876282 chr6:28092338 ZSCAN16 0.88 4.52 0.38 1.44e-5 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs4919044 0.756 rs2478239 chr10:94806370 A/T cg05127821 chr10:94822908 CYP26C1 -0.8 -5.15 -0.42 9.92e-7 Coronary artery disease; TGCT cis rs2836974 0.796 rs77153312 chr21:40695499 G/A cg17971929 chr21:40555470 PSMG1 0.96 8.47 0.61 6.08e-14 Cognitive function; TGCT cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg25036284 chr2:26402008 FAM59B -0.65 -5.18 -0.42 8.8e-7 Gut microbiome composition (summer); TGCT cis rs12579753 0.879 rs11115010 chr12:82165895 G/T cg21231944 chr12:82153410 PPFIA2 -0.34 -4.62 -0.38 9.52e-6 Resting heart rate; TGCT trans rs1814175 0.765 rs11493326 chr11:50018063 T/C cg11707556 chr5:10655725 ANKRD33B -0.36 -6.98 -0.53 1.55e-10 Height; TGCT cis rs11148252 0.538 rs2296348 chr13:52710136 T/G cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.84e-8 Lewy body disease; TGCT cis rs1059312 1.000 rs1059312 chr12:129278864 A/G cg09035930 chr12:129282057 SLC15A4 -0.57 -11.5 -0.72 2.76e-21 Systemic lupus erythematosus; TGCT cis rs12712073 0.845 rs1370353 chr2:100764824 G/C cg22139774 chr2:100720529 AFF3 -0.36 -5.65 -0.45 1.04e-7 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.846 rs1788196 chr8:101290088 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs6964587 1.000 rs2106171 chr7:91750450 A/G cg22709100 chr7:91322751 NA 0.29 4.66 0.39 8e-6 Breast cancer; TGCT cis rs17376456 0.825 rs17314797 chr5:93234845 T/A cg25358565 chr5:93447407 FAM172A 1.01 8.13 0.59 3.77e-13 Diabetic retinopathy; TGCT cis rs929354 0.772 rs6971896 chr7:156978412 C/T cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT trans rs77457752 0.690 rs12349345 chr9:13912075 T/C cg23609682 chr1:3070786 PRDM16 0.51 7.14 0.54 6.89e-11 Breast cancer; TGCT cis rs2486288 0.656 rs7166580 chr15:45571209 C/G cg26924012 chr15:45694286 SPATA5L1 -0.79 -7.87 -0.58 1.53e-12 Glomerular filtration rate; TGCT cis rs3935685 0.874 rs4595768 chr15:78006290 C/T cg25212270 chr15:78015279 NA 0.27 5.66 0.45 9.91e-8 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.554 rs13108359 chr4:152727852 T/C cg17479576 chr4:152424074 FAM160A1 0.51 5.21 0.42 7.5e-7 Intelligence (multi-trait analysis); TGCT cis rs9291683 0.567 rs12499857 chr4:9995376 G/A cg11266682 chr4:10021025 SLC2A9 0.67 8.95 0.63 4.3e-15 Bone mineral density; TGCT cis rs807669 0.903 rs807668 chr22:19162686 A/G cg02655711 chr22:19163373 SLC25A1 0.42 10.06 0.67 8.99e-18 Metabolite levels; TGCT cis rs7044106 0.791 rs7043969 chr9:123493989 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 7.24 0.54 4.22e-11 Hip circumference adjusted for BMI; TGCT cis rs2204008 0.563 rs2320512 chr12:38266913 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs7833790 0.724 rs6473311 chr8:82726682 G/A cg23324259 chr8:82754387 SNX16 -0.61 -4.71 -0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs909341 1.000 rs909341 chr20:62328742 C/T cg14758556 chr20:62440591 NA 0.3 4.56 0.38 1.23e-5 Atopic dermatitis; TGCT cis rs2594989 0.639 rs2442781 chr3:11483769 A/G cg00170343 chr3:11313890 ATG7 -0.6 -4.45 -0.37 1.9e-5 Circulating chemerin levels; TGCT cis rs12477438 0.520 rs13004491 chr2:99738008 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs35883536 0.588 rs17403878 chr1:101105310 C/T cg06223162 chr1:101003688 GPR88 0.33 5.54 0.45 1.7e-7 Monocyte count; TGCT cis rs9486719 1.000 rs13208422 chr6:96892119 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs9486719 1.000 rs2472888 chr6:96865501 T/C cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg16325326 chr1:53192061 ZYG11B -0.7 -8.6 -0.61 2.87e-14 Monocyte count; TGCT cis rs908922 0.676 rs533917 chr1:152518294 A/G cg20991723 chr1:152506922 NA 0.46 6.18 0.49 8.64e-9 Hair morphology; TGCT cis rs4919694 1.000 rs10509758 chr10:104681710 T/C cg04362960 chr10:104952993 NT5C2 1.02 6.9 0.53 2.41e-10 Arsenic metabolism; TGCT cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs7727544 0.684 rs272849 chr5:131690241 A/G cg24060327 chr5:131705240 SLC22A5 -0.59 -6.54 -0.51 1.43e-9 Blood metabolite levels; TGCT cis rs7715806 0.500 rs4703676 chr5:74979866 G/C cg19683494 chr5:74908142 NA 0.57 4.95 0.41 2.35e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg13395646 chr4:1353034 KIAA1530 -0.36 -4.61 -0.38 9.75e-6 Obesity-related traits; TGCT cis rs4325129 1.000 rs12141291 chr1:159460871 C/T cg07417683 chr1:159440267 NA -0.44 -4.54 -0.38 1.33e-5 Obesity-related traits; TGCT cis rs7714584 1.000 rs1428555 chr5:150257391 A/G cg22134413 chr5:150180641 NA -0.91 -7.16 -0.54 6.18e-11 Crohn's disease; TGCT cis rs9467773 0.595 rs6907924 chr6:26438817 T/G cg05738196 chr6:26577821 NA -0.52 -5.49 -0.44 2.18e-7 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.877 rs17083460 chr5:93462354 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs1218582 0.710 rs4845685 chr1:154878300 C/A cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.73e-7 Menopause (age at onset); TGCT trans rs1814175 0.645 rs1851857 chr11:49855589 A/C cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs727505 0.954 rs66691367 chr7:124654217 G/T cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs62244186 0.516 rs11922470 chr3:44777795 C/T cg10263370 chr3:44754102 ZNF502 -0.4 -4.46 -0.37 1.81e-5 Depressive symptoms; TGCT cis rs4919044 0.808 rs1222605 chr10:94804200 T/C cg05127821 chr10:94822908 CYP26C1 -0.75 -4.85 -0.4 3.67e-6 Coronary artery disease; TGCT cis rs9581857 0.547 rs9581872 chr13:28086058 C/T cg22138327 chr13:27999177 GTF3A 0.72 4.51 0.38 1.46e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6547741 1.000 rs6756238 chr2:27841305 G/A cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs4851266 0.898 rs12994592 chr2:100857984 T/C cg07810366 chr2:100720526 AFF3 -0.36 -5.21 -0.42 7.59e-7 Educational attainment; TGCT cis rs7599312 0.534 rs7596285 chr2:213406961 G/A cg16329650 chr2:213403929 ERBB4 1.07 16.1 0.82 3.53e-32 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6725041 0.819 rs1521660 chr2:213082960 C/T cg20637307 chr2:213403960 ERBB4 -0.52 -4.5 -0.37 1.54e-5 QT interval (ambient particulate matter interaction); TGCT cis rs9611565 0.729 rs203319 chr22:41914593 C/T cg03806693 chr22:41940476 POLR3H -1.0 -11.18 -0.71 1.68e-20 Vitiligo; TGCT cis rs9467711 0.659 rs13216828 chr6:26373507 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12791968 0.765 rs12226848 chr11:45009204 C/T cg11846598 chr11:44996168 LOC221122 -0.32 -5.01 -0.41 1.83e-6 Inhibitory control; TGCT cis rs637571 0.544 rs12361552 chr11:65701204 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.51 -5.13 -0.42 1.07e-6 Eosinophil percentage of white cells; TGCT cis rs651907 0.535 rs4342086 chr3:101503765 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs7100689 0.725 rs2185425 chr10:82139941 T/C cg01528321 chr10:82214614 TSPAN14 0.89 8.97 0.63 3.94e-15 Post bronchodilator FEV1; TGCT cis rs10504229 0.679 rs6474100 chr8:58031161 G/A cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs5744897 1.000 rs5744897 chr12:133226831 C/T cg17341477 chr12:133246679 POLE 0.35 4.74 0.39 5.78e-6 Urate levels in overweight individuals; TGCT cis rs9467711 0.538 rs35942482 chr6:26444938 T/A cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7191439 0.657 rs3826076 chr16:88780518 C/T cg27087555 chr16:88793112 FAM38A 0.44 5.13 0.42 1.1e-6 Plateletcrit; TGCT cis rs7681440 0.967 rs920624 chr4:90748195 T/A cg20003494 chr4:90757398 SNCA -0.54 -5.05 -0.41 1.56e-6 Dementia with Lewy bodies; TGCT cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.47 -0.37 1.72e-5 Bipolar disorder; TGCT cis rs7677751 0.806 rs73252942 chr4:55104604 T/C cg17187183 chr4:55093834 PDGFRA 0.54 7.0 0.53 1.45e-10 Corneal astigmatism; TGCT cis rs12134133 1.000 rs2782851 chr1:207465062 C/T cg02152968 chr1:207494213 CD55 0.57 4.47 0.37 1.74e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs11098499 0.863 rs13140409 chr4:120503460 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs9341808 0.714 rs4256394 chr6:80882142 C/T cg08355045 chr6:80787529 NA 0.28 4.76 0.39 5.39e-6 Sitting height ratio; TGCT cis rs12497850 0.897 rs9884022 chr3:48956862 G/C cg05785598 chr3:49045655 WDR6 0.36 4.76 0.39 5.34e-6 Parkinson's disease; TGCT cis rs7539409 0.651 rs7521788 chr1:84309320 G/T cg10977910 chr1:84465055 TTLL7 0.88 5.62 0.45 1.19e-7 Alzheimer's disease; TGCT cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg02458000 chr6:26745757 NA 0.58 5.75 0.46 6.43e-8 Intelligence (multi-trait analysis); TGCT cis rs35084382 1.000 rs2431663 chr5:172196711 A/C cg19801141 chr5:172198162 DUSP1 0.94 5.35 0.43 4.02e-7 Optic cup area; TGCT cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg04389838 chr3:44770851 ZNF501 -0.42 -5.72 -0.46 7.66e-8 Depressive symptoms; TGCT cis rs1568889 1.000 rs12791341 chr11:28335452 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.75 0.62 1.27e-14 Bipolar disorder; TGCT cis rs2486288 0.656 rs11639349 chr15:45568260 C/T cg26924012 chr15:45694286 SPATA5L1 -0.82 -8.09 -0.59 4.62e-13 Glomerular filtration rate; TGCT cis rs2932538 0.922 rs17438324 chr1:113100573 C/T cg22162597 chr1:113214053 CAPZA1 0.27 5.89 0.47 3.46e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT trans rs2727020 0.729 rs2204366 chr11:49349367 A/C cg03929089 chr4:120376271 NA 0.73 8.36 0.6 1.1e-13 Coronary artery disease; TGCT cis rs13326165 0.671 rs6794675 chr3:52374889 T/A cg27565382 chr3:53032988 SFMBT1 0.37 4.93 0.41 2.55e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg18252515 chr7:66147081 NA 1.22 7.33 0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs12971120 0.504 rs11665154 chr18:72147006 A/C cg26446133 chr18:72167187 CNDP2 -0.27 -5.25 -0.43 6.25e-7 Refractive error; TGCT cis rs922182 0.967 rs17788704 chr15:64277097 A/G cg02919090 chr15:64263738 DAPK2 -0.29 -5.48 -0.44 2.27e-7 Blood protein levels; TGCT cis rs7223966 0.960 rs8082651 chr17:61675292 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.23 0.43 6.88e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1395 0.778 rs4665959 chr2:27443256 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.42 0.65 3.12e-16 Blood metabolite levels; TGCT cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.92 -6.8 -0.52 3.96e-10 Gut microbiome composition (summer); TGCT trans rs7618501 0.521 rs11709573 chr3:49956628 C/T cg21659725 chr3:3221576 CRBN 0.68 7.55 0.56 8.1e-12 Intelligence (multi-trait analysis); TGCT cis rs2652822 0.550 rs11853804 chr15:63528256 C/A cg12855773 chr15:63363890 TPM1 -0.17 -5.21 -0.42 7.77e-7 Metabolic traits; TGCT cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6088590 0.561 rs6059926 chr20:33164804 C/T cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs7635838 0.859 rs2443708 chr3:11545719 T/C cg00170343 chr3:11313890 ATG7 0.61 5.28 0.43 5.69e-7 HDL cholesterol; TGCT cis rs7666738 0.830 rs6532723 chr4:99052147 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6969780 0.915 rs7341470 chr7:27184842 T/C cg04317399 chr7:27170313 HOXA4 -0.45 -4.53 -0.38 1.35e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2562456 1.000 rs2359155 chr19:21671869 C/A cg01304269 chr19:21688519 ZNF429 -0.58 -4.78 -0.39 4.79e-6 Pain; TGCT cis rs6840360 0.571 rs4696274 chr4:152528478 C/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT trans rs1974653 0.672 rs9606238 chr22:20070171 T/C cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs11190604 1.000 rs7088512 chr10:102303498 G/T cg23241863 chr10:102295624 HIF1AN 0.73 5.38 0.43 3.6e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs617219 0.726 rs1962002 chr5:78430689 T/C cg23987322 chr5:78407566 BHMT 0.35 4.58 0.38 1.14e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7772486 0.686 rs7739735 chr6:146123536 G/A cg23711669 chr6:146136114 FBXO30 0.86 9.53 0.65 1.74e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg20607798 chr8:58055168 NA 0.68 5.66 0.45 1e-7 Developmental language disorder (linguistic errors); TGCT cis rs67072384 1.000 rs72964181 chr11:72440124 C/G cg03713592 chr11:72463424 ARAP1 -0.92 -4.61 -0.38 9.81e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs17376456 0.877 rs9314101 chr5:93461593 A/T cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs2204008 0.576 rs11519979 chr12:37999413 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs36051895 0.589 rs7848312 chr9:5237442 T/C cg02405213 chr9:5042618 JAK2 -0.68 -8.01 -0.58 7.18e-13 Pediatric autoimmune diseases; TGCT cis rs3818285 0.504 rs4917547 chr10:111652285 T/C cg00817464 chr10:111662876 XPNPEP1 -0.29 -4.94 -0.41 2.46e-6 Superior crus of antihelix expression; TGCT cis rs155076 1.000 rs58519241 chr13:21845006 C/A cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs1371867 0.875 rs962452 chr8:101331369 G/A cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs868036 0.718 rs8030456 chr15:68076856 C/T cg05925327 chr15:68127851 NA -0.51 -4.94 -0.41 2.52e-6 Restless legs syndrome; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs7582180 0.676 rs1437969 chr2:100983482 A/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.97 -0.41 2.16e-6 Intelligence (multi-trait analysis); TGCT cis rs12188164 1.000 rs34453673 chr5:434722 G/C cg26850624 chr5:429559 AHRR -0.19 -4.74 -0.39 5.87e-6 Cystic fibrosis severity; TGCT cis rs2816958 0.803 rs2816956 chr1:200103564 T/C cg07971716 chr1:199773294 NA 0.43 4.48 0.37 1.7e-5 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs9611565 0.506 rs1883825 chr22:41703408 A/G cg06634786 chr22:41940651 POLR3H -0.58 -5.28 -0.43 5.62e-7 Vitiligo; TGCT cis rs10791097 0.653 rs11222362 chr11:130731425 T/C cg05962950 chr11:130786565 SNX19 0.84 10.71 0.69 2.4e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4819052 0.851 rs2236444 chr21:46678226 T/C cg06618935 chr21:46677482 NA -0.39 -5.85 -0.47 4.12e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT trans rs9329221 0.618 rs73197281 chr8:10263282 T/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.64 -0.51 9.01e-10 Neuroticism; TGCT cis rs7926906 0.840 rs7926034 chr11:90514796 A/G cg22332266 chr11:89956777 CHORDC1 -0.43 -4.55 -0.38 1.26e-5 Intelligence (multi-trait analysis); TGCT cis rs1031925 0.640 rs6445958 chr3:51772297 A/G cg10583097 chr3:51429234 RBM15B -0.52 -4.96 -0.41 2.26e-6 Melanoma; TGCT cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg15659132 chr6:26577336 NA 0.85 11.54 0.72 2.22e-21 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.629 rs74177696 chr2:100938481 C/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.37e-6 Intelligence (multi-trait analysis); TGCT cis rs8062405 0.823 rs7202948 chr16:28558289 T/A cg09754948 chr16:28834200 ATXN2L 0.63 4.97 0.41 2.19e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs67079557 1 rs67079557 chr15:75930300 ATAATAAG/A cg20655648 chr15:75932815 IMP3 0.61 4.88 0.4 3.24e-6 Breast cancer; TGCT cis rs17030434 1.000 rs952211 chr4:154717816 A/G cg14289246 chr4:154710475 SFRP2 -0.84 -5.35 -0.43 4.05e-7 Electrocardiographic conduction measures; TGCT cis rs7474896 0.515 rs2738203 chr10:38277596 G/A cg13720705 chr10:37990370 NA -0.42 -5.36 -0.43 3.95e-7 Obesity (extreme); TGCT cis rs4888262 0.526 rs4887777 chr16:74637821 A/G cg01733217 chr16:74700730 RFWD3 0.74 7.3 0.55 2.97e-11 Testicular germ cell tumor; TGCT cis rs2677744 1.000 rs2677744 chr15:91450441 A/G cg22288577 chr15:91498497 RCCD1 -0.44 -4.51 -0.38 1.49e-5 Attention deficit hyperactivity disorder; TGCT cis rs7267979 1.000 rs6050632 chr20:25432601 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611519 0.808 rs5751074 chr22:41665722 G/A cg06634786 chr22:41940651 POLR3H -0.58 -5.32 -0.43 4.72e-7 Neuroticism; TGCT cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg03351412 chr1:154909251 PMVK 0.52 4.91 0.4 2.77e-6 Prostate cancer; TGCT cis rs5750830 0.621 rs5757665 chr22:39821641 A/G cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs933688 1.000 rs1895448 chr5:90743854 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 9.32 0.64 5.46e-16 Smoking behavior; TGCT cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg00814883 chr7:100076585 TSC22D4 -0.89 -9.26 -0.64 7.79e-16 Platelet count; TGCT cis rs1577917 0.696 rs2842603 chr6:86336337 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.51 -4.65 -0.39 8.52e-6 Response to antipsychotic treatment; TGCT cis rs13064411 0.696 rs9808893 chr3:113228444 G/A cg18753928 chr3:113234510 CCDC52 -0.71 -5.78 -0.46 5.63e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs3782455 0.793 rs2290800 chr12:114404383 T/G cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9527 0.590 rs7906754 chr10:104782557 T/C cg15744005 chr10:104629667 AS3MT -0.42 -4.92 -0.4 2.74e-6 Arsenic metabolism; TGCT trans rs459571 0.959 rs410876 chr9:136893867 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.73 -8.01 -0.58 7.15e-13 Platelet distribution width; TGCT cis rs2204008 0.905 rs8189449 chr12:38437377 C/A cg26384229 chr12:38710491 ALG10B 0.83 7.46 0.56 1.32e-11 Bladder cancer; TGCT cis rs4074961 0.586 rs10908360 chr1:38058693 T/C cg17933807 chr1:38061675 GNL2 0.94 10.45 0.68 1e-18 Axial length; TGCT cis rs68170813 0.559 rs74387778 chr7:106963213 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs1023500 0.573 rs13057094 chr22:42470317 T/C cg05082376 chr22:42548792 NA -0.22 -5.37 -0.43 3.69e-7 Schizophrenia; TGCT cis rs709400 1.000 rs3783404 chr14:104118498 A/G cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs12908161 0.959 rs35557864 chr15:85331629 A/G cg17173187 chr15:85201210 NMB 0.55 6.11 0.48 1.17e-8 Schizophrenia; TGCT cis rs6912958 0.781 rs9450755 chr6:88303702 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.57 -0.38 1.14e-5 Monocyte percentage of white cells; TGCT cis rs68170813 0.559 rs75007274 chr7:106814543 G/A cg02696742 chr7:106810147 HBP1 -0.7 -6.05 -0.48 1.59e-8 Coronary artery disease; TGCT cis rs10791323 0.569 rs2298738 chr11:133715153 G/C cg15485101 chr11:133734466 NA 0.4 5.02 0.41 1.78e-6 Childhood ear infection; TGCT cis rs16958440 0.867 rs77149690 chr18:44697143 T/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.08 0.48 1.39e-8 Bipolar disorder; TGCT cis rs62380364 0.542 rs601499 chr5:88052687 A/C cg22951263 chr5:87985283 NA -0.59 -6.32 -0.49 4.34e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs2114425 chr4:99023967 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.62 0.56 5.53e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs765787 0.530 rs28396110 chr15:45536909 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs2742417 0.603 rs2742398 chr3:45759036 A/G cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs11711311 1.000 rs9865965 chr3:113450495 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs4665630 0.614 rs6739646 chr2:23946840 A/C cg08063864 chr2:24346004 PFN4;LOC375190 -1.23 -5.86 -0.47 3.98e-8 Hypertension; TGCT cis rs11096990 0.656 rs3796513 chr4:39291082 G/A cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs9303401 0.659 rs34913878 chr17:56897094 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs2549003 1.000 rs2070724 chr5:131822072 A/G cg21138405 chr5:131827807 IRF1 0.19 4.79 0.39 4.76e-6 Asthma (sex interaction); TGCT cis rs12220238 0.908 rs10824086 chr10:75912668 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1371867 0.817 rs1660314 chr8:101332953 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg06675538 chr2:114033490 PAX8;LOC440839 -0.42 -4.65 -0.39 8.23e-6 Lymphocyte counts; TGCT cis rs4973397 0.774 rs12998237 chr2:232276651 T/C cg09339159 chr2:232260559 B3GNT7 0.53 4.53 0.38 1.36e-5 Anti-saccade response; TGCT cis rs9611565 0.649 rs2413659 chr22:42164862 A/G cg06634786 chr22:41940651 POLR3H 0.78 7.34 0.55 2.49e-11 Vitiligo; TGCT cis rs5769765 1.000 rs4597652 chr22:50270570 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs11779988 0.503 rs411173 chr8:17768264 G/A cg01800426 chr8:17659068 MTUS1 -0.73 -5.71 -0.46 7.76e-8 Breast cancer; TGCT cis rs36051895 0.589 rs10122037 chr9:5192874 A/G cg02405213 chr9:5042618 JAK2 0.66 8.36 0.6 1.08e-13 Pediatric autoimmune diseases; TGCT cis rs56176327 0.583 rs7613603 chr3:49812866 C/T cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.75 -0.39 5.61e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs7191439 0.522 rs4597303 chr16:88763561 T/C cg27087555 chr16:88793112 FAM38A -0.51 -4.57 -0.38 1.15e-5 Plateletcrit; TGCT cis rs9457247 1.000 rs429083 chr6:167383972 T/C cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs2204008 0.837 rs73112346 chr12:38357606 C/T cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.87e-6 Bladder cancer; TGCT cis rs1577917 1.000 rs12665321 chr6:86769289 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.86e-7 Response to antipsychotic treatment; TGCT cis rs111332265 1 rs111332265 chr5:150393107 A/G cg22134413 chr5:150180641 NA 0.82 5.07 0.41 1.43e-6 Tumor necrosis factor alpha levels; TGCT cis rs9910055 0.762 rs4239142 chr17:42205876 A/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.25 -4.45 -0.37 1.88e-5 Total body bone mineral density; TGCT cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.14 0.42 1.06e-6 Platelet count; TGCT trans rs931812 0.757 rs4734014 chr8:101908844 A/G cg20993868 chr7:22813445 NA 0.32 6.68 0.51 7.28e-10 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs9372498 0.505 rs62424202 chr6:118851027 T/C cg07617317 chr6:118971624 C6orf204 0.51 5.42 0.44 3e-7 Diastolic blood pressure; TGCT cis rs7772486 0.875 rs6914813 chr6:146397798 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.8 0.4 4.41e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs875971 0.867 rs1002053 chr7:65798545 G/A cg11764359 chr7:65958608 NA -0.61 -5.51 -0.44 1.96e-7 Aortic root size; TGCT trans rs1814175 0.817 rs4405313 chr11:50013636 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs1395 0.626 rs72817537 chr2:27497549 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 8.02 0.58 6.76e-13 Blood metabolite levels; TGCT cis rs425277 1.000 rs262647 chr1:2095699 C/T cg03732007 chr1:2071316 PRKCZ 0.26 5.52 0.44 1.89e-7 Height; TGCT cis rs12681287 0.640 rs4961193 chr8:87486168 C/T cg19078186 chr8:87526527 CPNE3 0.36 4.63 0.38 9.24e-6 Caudate activity during reward; TGCT cis rs11785400 0.793 rs35985277 chr8:143736137 C/T cg24634471 chr8:143751801 JRK 0.54 5.33 0.43 4.51e-7 Schizophrenia; TGCT cis rs11190604 1.000 rs2495752 chr10:102326115 T/C cg16342193 chr10:102329863 NA -0.4 -5.08 -0.42 1.32e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10791323 0.604 rs2723607 chr11:133711018 C/G cg15485101 chr11:133734466 NA 0.39 5.12 0.42 1.15e-6 Childhood ear infection; TGCT cis rs1971762 0.563 rs7975862 chr12:54078427 A/C cg16917193 chr12:54089295 NA -1.33 -18.03 -0.85 1.9e-36 Height; TGCT cis rs7666738 0.546 rs13149516 chr4:98913030 T/A cg17366294 chr4:99064904 C4orf37 0.64 5.88 0.47 3.54e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg02725872 chr8:58115012 NA -0.4 -5.09 -0.42 1.31e-6 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs6967745 chr7:106850548 G/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs1005277 0.563 rs2800550 chr10:38482929 T/C cg25427524 chr10:38739819 LOC399744 -0.41 -8.54 -0.61 4.04e-14 Extrinsic epigenetic age acceleration; TGCT cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg06697600 chr4:7070879 GRPEL1 -0.45 -4.74 -0.39 5.72e-6 Monocyte percentage of white cells; TGCT cis rs992157 0.932 rs1870125 chr2:219187901 C/T cg00012203 chr2:219082015 ARPC2 0.7 6.92 0.53 2.19e-10 Colorectal cancer; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg11965913 chr1:205819406 PM20D1 0.52 7.21 0.54 4.73e-11 Menarche (age at onset); TGCT cis rs7582180 0.568 rs10186134 chr2:100939501 T/A cg14675211 chr2:100938903 LONRF2 0.47 4.57 0.38 1.16e-5 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.875 rs854148 chr6:146310979 G/C cg13319975 chr6:146136371 FBXO30 -0.53 -4.68 -0.39 7.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs3847687 1.000 rs3847688 chr12:131525310 C/T cg13586425 chr12:131519906 GPR133 -0.33 -5.26 -0.43 6.17e-7 Longevity; TGCT cis rs7267979 0.966 rs2482918 chr20:25412135 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7523273 0.606 rs2488253 chr1:207938709 C/A cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs13256369 0.851 rs13258283 chr8:8563630 T/C cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs79387448 0.638 rs76255660 chr2:103091028 T/C cg09003973 chr2:102972529 NA 1.32 9.88 0.66 2.54e-17 Gut microbiota (bacterial taxa); TGCT cis rs2637266 0.678 rs1660918 chr10:78511674 T/A cg18941641 chr10:78392320 NA 0.4 4.79 0.4 4.63e-6 Pulmonary function; TGCT cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs597539 0.652 rs553875 chr11:68695144 T/G cg06028808 chr11:68637592 NA 0.52 6.76 0.52 4.92e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs636291 0.517 rs2781233 chr1:10529194 T/C cg17425144 chr1:10567563 PEX14 0.53 7.44 0.56 1.43e-11 Prostate cancer; TGCT trans rs57221529 0.709 rs72703034 chr5:577101 C/T cg25482853 chr8:67687455 SGK3 1.16 10.5 0.69 7.91e-19 Lung disease severity in cystic fibrosis; TGCT cis rs9611519 0.579 rs8136274 chr22:41415311 T/C cg13695892 chr22:41940480 POLR3H -0.54 -5.1 -0.42 1.21e-6 Neuroticism; TGCT cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg09904177 chr6:26538194 HMGN4 0.65 6.02 0.48 1.8e-8 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.647 rs11634266 chr15:77093461 A/G cg23625390 chr15:77176239 SCAPER -0.38 -4.83 -0.4 4.01e-6 Blood metabolite levels; TGCT cis rs2016266 0.784 rs6421176 chr12:53654052 A/G cg16917193 chr12:54089295 NA 0.65 4.74 0.39 5.67e-6 Bone mineral density (spine);Bone mineral density; TGCT trans rs5770872 0.511 rs56168974 chr22:50831338 A/G cg09860653 chr1:19970708 NBL1 -0.75 -6.81 -0.52 3.82e-10 Tonsillectomy; TGCT cis rs9914988 0.943 rs3181215 chr17:27077331 C/T cg20469991 chr17:27169893 C17orf63 0.63 4.73 0.39 5.92e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs36051895 0.623 rs2381215 chr9:5262607 C/T cg02405213 chr9:5042618 JAK2 -0.61 -7.38 -0.55 2.05e-11 Pediatric autoimmune diseases; TGCT cis rs4919694 0.536 rs12256506 chr10:104963618 T/A cg04362960 chr10:104952993 NT5C2 0.96 6.68 0.51 7.03e-10 Arsenic metabolism; TGCT cis rs7909074 1.000 rs4948926 chr10:45392604 G/C cg04218760 chr10:45406644 TMEM72 -0.27 -5.55 -0.45 1.64e-7 Mean corpuscular volume; TGCT cis rs9921192 1.000 rs12444637 chr16:4345448 T/C cg00021532 chr16:4324280 TFAP4 0.83 9.25 0.64 8.33e-16 Prostate-specific antigen levels; TGCT cis rs2880765 0.566 rs12911430 chr15:86011264 A/T cg13263323 chr15:86062960 AKAP13 -0.22 -4.85 -0.4 3.66e-6 Coronary artery disease; TGCT cis rs9640161 0.659 rs11974980 chr7:150009838 C/T cg17279839 chr7:150038598 RARRES2 0.42 4.45 0.37 1.88e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs9894429 1.000 rs12948099 chr17:79600799 C/G cg21028142 chr17:79581711 NPLOC4 0.3 6.98 0.53 1.57e-10 Eye color traits; TGCT cis rs10089 0.904 rs3087889 chr5:127524944 T/A cg19767477 chr5:127420684 SLC12A2 -0.44 -4.68 -0.39 7.35e-6 Ileal carcinoids; TGCT cis rs9583531 0.527 rs9515274 chr13:111390429 A/G cg24331049 chr13:111365604 ING1 0.75 7.38 0.55 1.97e-11 Coronary artery disease; TGCT cis rs68170813 0.559 rs74906766 chr7:106885236 T/A cg02696742 chr7:106810147 HBP1 -0.65 -5.38 -0.43 3.63e-7 Coronary artery disease; TGCT cis rs2153535 0.580 rs3938660 chr6:8443335 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs10751667 0.961 rs7480178 chr11:927108 T/C cg06064525 chr11:970664 AP2A2 -0.31 -6.11 -0.48 1.19e-8 Alzheimer's disease (late onset); TGCT cis rs2013441 0.669 rs62066947 chr17:20351458 G/A cg18979559 chr17:20280153 CCDC144C 0.55 5.73 0.46 7.29e-8 Obesity-related traits; TGCT cis rs13191362 1.000 rs35818596 chr6:163001874 C/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs797680 0.964 rs2296558 chr1:93736555 C/T cg17826107 chr1:92977322 EVI5 0.23 5.15 0.42 9.77e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs561341 0.681 rs56064462 chr17:30235116 G/A cg20587970 chr11:113659929 NA -0.69 -9.4 -0.65 3.52e-16 Hip circumference adjusted for BMI; TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg18765753 chr7:1198926 ZFAND2A -0.53 -6.72 -0.52 6.02e-10 Longevity;Endometriosis; TGCT cis rs9952991 0.941 rs2014857 chr18:12774326 C/T cg09945482 chr18:12777974 NA 0.5 4.75 0.39 5.61e-6 Inflammatory skin disease; TGCT cis rs10789491 1.000 rs4660956 chr1:47158486 A/G cg15501359 chr1:47185051 KIAA0494 0.82 7.78 0.57 2.38e-12 Response to hepatitis C treatment; TGCT cis rs13082711 0.522 rs514668 chr3:27330972 A/G cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs6598955 0.724 rs10902731 chr1:26600793 A/G cg04990556 chr1:26633338 UBXN11 -0.9 -11.22 -0.71 1.34e-20 Obesity-related traits; TGCT cis rs317865 0.737 rs28483204 chr4:16205098 A/G cg04764131 chr4:16228633 TAPT1;FLJ39653 0.77 5.08 0.42 1.32e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6893807 0.778 rs13174131 chr5:87959538 T/G cg24804195 chr5:87968844 LOC645323 0.82 5.1 0.42 1.24e-6 Body mass index; TGCT cis rs910316 1.000 rs7156328 chr14:75532941 T/C cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs2840044 1.000 rs225243 chr17:33947212 A/G cg05299278 chr17:33885742 SLFN14 0.23 5.07 0.41 1.39e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs58688157 0.924 rs35865896 chr11:584591 A/G cg16486109 chr11:613632 IRF7 0.35 5.08 0.42 1.34e-6 Systemic lupus erythematosus; TGCT cis rs13256369 0.950 rs1522839 chr8:8580453 C/T cg18904891 chr8:8559673 CLDN23 0.63 5.47 0.44 2.36e-7 Obesity-related traits; TGCT cis rs6748734 0.543 rs73012754 chr2:241754034 G/A cg04034577 chr2:241836375 C2orf54 0.32 5.12 0.42 1.15e-6 Urinary metabolites; TGCT cis rs17539620 0.506 rs62432749 chr6:154839219 G/A cg20019720 chr6:154832845 CNKSR3 0.57 4.99 0.41 2.02e-6 Lipoprotein (a) levels; TGCT cis rs778371 0.723 rs12619195 chr2:233678326 G/A cg08000102 chr2:233561755 GIGYF2 -0.72 -8.68 -0.61 1.91e-14 Schizophrenia; TGCT cis rs17376456 0.932 rs3940842 chr5:93534858 C/A cg21475434 chr5:93447410 FAM172A 0.61 4.51 0.38 1.47e-5 Diabetic retinopathy; TGCT cis rs3820928 0.874 rs2229813 chr2:227892720 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs10791097 0.720 rs6590515 chr11:130733365 A/G cg14779329 chr11:130786720 SNX19 -0.29 -5.1 -0.42 1.24e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11148252 0.564 rs2296350 chr13:52710044 T/C cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.84e-8 Lewy body disease; TGCT cis rs7829975 0.742 rs1533058 chr8:8685190 A/G cg06636001 chr8:8085503 FLJ10661 0.67 6.12 0.48 1.13e-8 Mood instability; TGCT cis rs2013441 1.000 rs1561974 chr17:20196144 G/A cg23224458 chr17:20280056 CCDC144C -0.42 -4.91 -0.4 2.82e-6 Obesity-related traits; TGCT cis rs7617773 0.676 rs13060020 chr3:48372646 C/T cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs10791097 0.694 rs2155751 chr11:130755240 G/A cg12179176 chr11:130786555 SNX19 0.82 10.15 0.67 5.45e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9611565 0.694 rs11090056 chr22:42095904 A/C cg06481639 chr22:41940642 POLR3H 0.57 4.86 0.4 3.51e-6 Vitiligo; TGCT cis rs7674212 0.570 rs12501621 chr4:104095505 T/G cg16532752 chr4:104119610 CENPE -0.61 -5.67 -0.45 9.45e-8 Type 2 diabetes; TGCT cis rs1061377 1.000 rs10027813 chr4:39121438 T/A cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs12210905 0.688 rs12212348 chr6:27361242 T/C cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs6558174 0.863 rs17746902 chr8:22491980 A/C cg03733263 chr8:22462867 KIAA1967 -0.57 -4.88 -0.4 3.14e-6 Breast cancer; TGCT cis rs2115630 0.691 rs2292462 chr15:85200754 G/T cg12863693 chr15:85201151 NMB -0.42 -5.7 -0.46 8.25e-8 P wave terminal force; TGCT cis rs9859260 0.744 rs419059 chr3:195782184 C/T cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs7666738 0.830 rs1426672 chr4:98923984 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs909341 0.537 rs4809334 chr20:62384972 G/A cg14758556 chr20:62440591 NA 0.38 5.44 0.44 2.7e-7 Atopic dermatitis; TGCT cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.97 12.73 0.75 2.98e-24 Prudent dietary pattern; TGCT cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs832540 0.830 rs252907 chr5:56120646 G/A cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Coronary artery disease; TGCT cis rs11030122 0.661 rs10835561 chr11:4087594 C/T cg18678763 chr11:4115507 RRM1 -0.46 -5.67 -0.45 9.61e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs2469997 0.858 rs2470031 chr8:120370390 T/A cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs6770219 0.516 rs57506565 chr3:186139358 T/C cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs2806561 0.765 rs652706 chr1:23514246 G/A cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs2921073 0.604 rs2979140 chr8:8267202 T/A cg06636001 chr8:8085503 FLJ10661 0.55 4.72 0.39 6.21e-6 Parkinson's disease; TGCT cis rs4727027 0.901 rs4727017 chr7:148822062 A/G cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2439831 0.717 rs7165471 chr15:43644788 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs909674 0.731 rs4821897 chr22:39835587 A/G cg02038168 chr22:39784481 NA -0.74 -5.59 -0.45 1.35e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9393692 0.905 rs989134 chr6:26336224 A/C cg13736514 chr6:26305472 NA -0.36 -5.11 -0.42 1.21e-6 Educational attainment; TGCT cis rs6840360 0.642 rs1443089 chr4:152450300 A/G cg17479576 chr4:152424074 FAM160A1 -0.62 -6.73 -0.52 5.67e-10 Intelligence (multi-trait analysis); TGCT cis rs911555 0.755 rs2756135 chr14:103962579 G/A cg12935359 chr14:103987150 CKB 0.32 4.5 0.37 1.57e-5 Intelligence (multi-trait analysis); TGCT cis rs9296092 0.517 rs7743445 chr6:33470600 G/T cg13560919 chr6:33536144 NA -0.22 -4.49 -0.37 1.6e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg07092213 chr7:1199455 ZFAND2A -0.49 -5.52 -0.44 1.87e-7 Longevity;Endometriosis; TGCT cis rs16870629 0.541 rs2334955 chr5:1062444 A/G cg00278107 chr5:1061253 SLC12A7 -0.35 -7.67 -0.57 4.42e-12 QT interval; TGCT cis rs7824557 0.564 rs34389419 chr8:11229319 C/G cg21775007 chr8:11205619 TDH -0.6 -5.61 -0.45 1.27e-7 Retinal vascular caliber; TGCT cis rs9296092 0.538 rs78061112 chr6:33526587 T/G cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs11096990 0.551 rs11724855 chr4:39164999 G/A cg20847110 chr4:39482781 LOC401127 0.17 4.86 0.4 3.49e-6 Cognitive function; TGCT cis rs6988636 1.000 rs13260775 chr8:124190167 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs6665290 0.839 rs6699400 chr1:227190497 A/G cg10327440 chr1:227177885 CDC42BPA -1.01 -21.05 -0.88 9.26e-43 Myeloid white cell count; TGCT cis rs6665290 0.870 rs17600725 chr1:227204231 A/G cg10327440 chr1:227177885 CDC42BPA -0.92 -16.67 -0.83 1.9e-33 Myeloid white cell count; TGCT cis rs6484504 0.532 rs12788257 chr11:31255045 T/C cg14844989 chr11:31128820 NA -0.25 -4.89 -0.4 3e-6 Red blood cell count; TGCT cis rs2832191 1.000 rs2832183 chr21:30482150 G/A cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs2204008 0.774 rs11520237 chr12:38266978 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.19e-11 Bladder cancer; TGCT cis rs644799 0.965 rs549695 chr11:95617788 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.84 9.93 0.67 1.91e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1697139 0.563 rs6859520 chr5:66529020 C/T cg11553311 chr5:66541588 NA 0.3 6.37 0.5 3.36e-9 Breast cancer; TGCT cis rs751728 1.000 rs2296747 chr6:33744882 C/G cg00334056 chr6:33755658 LEMD2 -0.26 -4.72 -0.39 6.25e-6 Crohn's disease; TGCT cis rs3027009 0.881 rs56184975 chr1:159149253 G/T cg24432768 chr1:158149974 CD1D -0.55 -4.76 -0.39 5.41e-6 Lean body mass and age at menarche (combined); TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg08859206 chr1:53392774 SCP2 -0.41 -6.31 -0.49 4.48e-9 Monocyte count; TGCT cis rs941873 0.772 rs2000404 chr10:81109708 T/C cg09469691 chr10:81107165 PPIF 0.5 4.96 0.41 2.27e-6 Height; TGCT cis rs3617 0.573 rs13072537 chr3:52896032 C/A cg11645453 chr3:52864694 ITIH4 0.26 4.96 0.41 2.24e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4460629 0.680 rs10796938 chr1:155072055 C/A cg23973274 chr1:155060172 NA -0.26 -4.66 -0.39 7.99e-6 Serum magnesium levels; TGCT cis rs6674176 0.561 rs12127226 chr1:44395309 C/T cg13606994 chr1:44402422 ARTN -0.5 -5.48 -0.44 2.3e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs4819052 0.851 rs9974891 chr21:46680767 T/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.62 0.38 9.36e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1580019 0.587 rs6951955 chr7:32548761 A/T cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.96 0.41 2.25e-6 Cognitive ability; TGCT cis rs10484885 0.887 rs2273246 chr6:90453263 A/G cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.66 -0.39 7.9e-6 QRS interval (sulfonylurea treatment interaction); TGCT cis rs17122693 0.748 rs76141309 chr14:51110947 A/C cg04730355 chr14:51134070 SAV1 1.04 6.2 0.49 7.67e-9 Cognitive performance; TGCT cis rs7267979 0.789 rs6083810 chr20:25329759 T/A cg16686733 chr20:25566563 NINL -0.49 -4.62 -0.38 9.44e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12220238 0.822 rs10824193 chr10:76261759 G/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 5.7 0.46 8.36e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg09323728 chr8:95962352 TP53INP1 -0.48 -6.19 -0.49 7.95e-9 Type 2 diabetes; TGCT cis rs7226408 0.948 rs11665141 chr18:34374865 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.56 0.38 1.2e-5 Obesity-related traits; TGCT cis rs3780378 0.935 rs6476939 chr9:5084837 T/A cg02405213 chr9:5042618 JAK2 -0.62 -8.18 -0.59 2.86e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9309473 0.660 rs11679594 chr2:73779507 G/A cg07208825 chr2:73871855 ALMS1P 0.23 4.48 0.37 1.65e-5 Metabolite levels; TGCT cis rs6450176 1.000 rs3776705 chr5:53304955 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs11690935 0.655 rs12997093 chr2:172564438 A/G cg13550731 chr2:172543902 DYNC1I2 0.67 5.86 0.47 3.89e-8 Schizophrenia; TGCT cis rs911263 0.961 rs7148882 chr14:68740924 A/G cg18825221 chr14:68749962 RAD51L1 -0.28 -5.47 -0.44 2.41e-7 Primary biliary cholangitis; TGCT cis rs453301 0.686 rs7814328 chr8:8876229 T/C cg11995313 chr8:8860691 ERI1 0.53 4.63 0.38 8.93e-6 Joint mobility (Beighton score); TGCT cis rs79349575 0.783 rs15563 chr17:47005193 A/G cg00947319 chr17:47005597 UBE2Z -0.21 -4.88 -0.4 3.21e-6 Type 2 diabetes; TGCT cis rs1215050 0.791 rs503863 chr4:98707663 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12477438 0.834 rs1563108 chr2:99701153 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.12 -0.48 1.13e-8 Chronic sinus infection; TGCT cis rs4988958 0.527 rs3771155 chr2:103037826 A/G cg03938978 chr2:103052716 IL18RAP 0.27 5.4 0.44 3.31e-7 Asthma (childhood onset); TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs35306767 0.953 rs35693858 chr10:979813 C/T cg18964960 chr10:1102726 WDR37 0.56 4.47 0.37 1.74e-5 Eosinophil percentage of granulocytes; TGCT cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.41 4.6 0.38 1.03e-5 Blood metabolite levels; TGCT cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg14004847 chr7:1930337 MAD1L1 -0.26 -4.46 -0.37 1.83e-5 Schizophrenia; TGCT cis rs8062405 1.000 rs4788102 chr16:28873398 G/A cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7568458 0.709 rs762684 chr2:85782023 G/A cg02493740 chr2:85810744 VAMP5 -0.28 -5.37 -0.43 3.67e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10875746 0.669 rs10467101 chr12:48607737 T/C cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT trans rs1814175 0.904 rs1846289 chr11:49620253 G/A cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs2354432 0.607 rs11587707 chr1:146707186 T/C cg25205988 chr1:146714368 CHD1L -1.15 -4.8 -0.4 4.49e-6 Mitochondrial DNA levels; TGCT cis rs1982963 1.000 rs753051 chr14:52505360 A/G cg10843707 chr14:52510701 NID2 -0.43 -6.6 -0.51 1.09e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2295359 1.000 rs10889661 chr1:67625309 T/A cg12940439 chr1:67600707 NA 0.54 5.72 0.46 7.49e-8 Psoriasis; TGCT cis rs7666738 0.830 rs7659420 chr4:98878714 G/C cg17366294 chr4:99064904 C4orf37 0.74 7.62 0.56 5.55e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2013441 1.000 rs2703780 chr17:20143672 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs9372498 0.505 rs62422248 chr6:118987610 T/C cg21191810 chr6:118973309 C6orf204 -0.38 -4.95 -0.41 2.39e-6 Diastolic blood pressure; TGCT cis rs2836950 0.502 rs12627205 chr21:40630027 C/T cg11644478 chr21:40555479 PSMG1 -0.55 -5.18 -0.42 8.7e-7 Menarche (age at onset); TGCT cis rs12477438 0.834 rs1563107 chr2:99701276 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.66 5.78 0.46 5.58e-8 Chronic sinus infection; TGCT cis rs9427116 0.502 rs903323 chr1:154572228 A/G cg17218026 chr1:154582156 ADAR -0.3 -7.91 -0.58 1.21e-12 Blood protein levels; TGCT cis rs9325144 0.555 rs2387855 chr12:38687964 T/G cg26384229 chr12:38710491 ALG10B 0.66 6.12 0.48 1.11e-8 Morning vs. evening chronotype; TGCT cis rs477895 1.000 rs7947143 chr11:64090422 G/A cg23719950 chr11:63933701 MACROD1 -0.59 -4.6 -0.38 1.01e-5 Mean platelet volume; TGCT cis rs710216 0.571 rs11210772 chr1:43448499 A/G cg03128534 chr1:43423976 SLC2A1 -0.55 -4.68 -0.39 7.25e-6 Red cell distribution width; TGCT cis rs9894429 0.789 rs7502346 chr17:79603741 T/C cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs1580019 0.522 rs10951340 chr7:32562408 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.86 0.4 3.43e-6 Cognitive ability; TGCT cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg22920501 chr2:26401640 FAM59B -0.78 -6.16 -0.48 9.43e-9 Gut microbiome composition (summer); TGCT cis rs3733585 0.699 rs6852441 chr4:9973744 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.68 -0.57 4.13e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9291683 0.632 rs11734786 chr4:10041499 A/C cg00071950 chr4:10020882 SLC2A9 0.68 8.73 0.62 1.45e-14 Bone mineral density; TGCT cis rs514406 0.758 rs532242 chr1:53308665 C/G cg01802117 chr1:53393560 SCP2 -0.42 -4.93 -0.41 2.54e-6 Monocyte count; TGCT cis rs1403694 0.515 rs1648697 chr3:186449194 A/G cg12454167 chr3:186435060 KNG1 0.46 7.19 0.54 5.47e-11 Blood protein levels; TGCT cis rs644799 1.000 rs12291986 chr11:95523030 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7666738 0.830 rs13147768 chr4:98833675 A/T cg18180107 chr4:99064573 C4orf37 0.56 5.18 0.42 8.78e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs858239 0.899 rs28635122 chr7:23310181 C/T cg05602783 chr7:23145260 KLHL7 -0.66 -5.26 -0.43 6.04e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9796 0.621 rs2578655 chr15:41462809 T/G cg18705301 chr15:41695430 NDUFAF1 -0.54 -7.22 -0.54 4.66e-11 Menopause (age at onset); TGCT cis rs2380220 0.576 rs4368819 chr6:96031109 T/G cg04719120 chr6:96025338 MANEA 0.73 5.48 0.44 2.31e-7 Behavioural disinhibition (generation interaction); TGCT cis rs9611565 0.592 rs5996039 chr22:41981957 A/G cg03806693 chr22:41940476 POLR3H -1.01 -10.2 -0.68 4.07e-18 Vitiligo; TGCT cis rs950027 0.596 rs2467853 chr15:45698793 T/G cg26924012 chr15:45694286 SPATA5L1 0.8 9.1 0.63 1.83e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs7267979 0.565 rs13040726 chr20:25559881 T/G cg03522245 chr20:25566470 NINL -0.44 -4.59 -0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs41271473 0.526 rs10916344 chr1:228737489 C/T cg16512390 chr1:228756714 NA 0.72 4.44 0.37 1.96e-5 Chronic lymphocytic leukemia; TGCT cis rs1568079 0.516 rs1571424 chr10:125220311 G/A cg04278168 chr10:124578263 NA -0.42 -4.62 -0.38 9.35e-6 Body mass index; TGCT cis rs854765 0.583 rs8065970 chr17:17858771 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs7191439 0.522 rs745326 chr16:88755245 C/G cg26511997 chr16:89237975 CDH15 0.82 4.44 0.37 1.98e-5 Plateletcrit; TGCT cis rs7246657 0.653 rs10401525 chr19:37658979 C/G cg24025825 chr19:37761650 NA -0.33 -5.06 -0.41 1.49e-6 Coronary artery calcification; TGCT cis rs7772486 0.840 rs2474355 chr6:146312540 C/G cg23711669 chr6:146136114 FBXO30 0.84 9.07 0.63 2.25e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2228479 0.572 rs62054252 chr16:89896834 G/A cg06558623 chr16:89946397 TCF25 0.55 4.77 0.39 5.13e-6 Skin colour saturation; TGCT trans rs2727020 0.658 rs4980440 chr11:49386017 C/T cg15704280 chr7:45808275 SEPT13 -0.74 -8.21 -0.59 2.38e-13 Coronary artery disease; TGCT cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs3099143 1.000 rs10431768 chr15:77162158 A/G cg21673338 chr15:77095150 SCAPER 0.54 5.15 0.42 1.01e-6 Recalcitrant atopic dermatitis; TGCT cis rs2839186 0.867 rs13050387 chr21:47701423 C/T cg13732083 chr21:47605072 C21orf56 0.34 4.52 0.38 1.44e-5 Testicular germ cell tumor; TGCT cis rs40363 0.645 rs250630 chr16:3524242 C/T cg21433313 chr16:3507492 NAT15 0.39 5.08 0.41 1.36e-6 Tuberculosis; TGCT cis rs11677416 1.000 rs1040193 chr2:113530099 C/T cg27083787 chr2:113543245 IL1A 0.18 4.5 0.37 1.53e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs8103278 0.826 rs11669442 chr19:46374557 A/G cg11657440 chr19:46296263 DMWD -0.63 -6.05 -0.48 1.62e-8 Coronary artery disease; TGCT cis rs1577917 0.958 rs114467802 chr6:86572350 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs362272 0.505 rs10155132 chr4:3369500 A/G cg06533319 chr4:3265114 C4orf44 -0.27 -5.6 -0.45 1.3e-7 Serum sulfate level; TGCT cis rs3741404 0.791 rs7112960 chr11:63907079 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.88 9.59 0.65 1.28e-16 Platelet count; TGCT cis rs4730250 0.655 rs4727671 chr7:106876045 A/G cg02696742 chr7:106810147 HBP1 -0.66 -5.51 -0.44 1.94e-7 Osteoarthritis; TGCT cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs12210905 0.688 rs72839471 chr6:27316959 C/T cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs10225163 0.590 rs10266923 chr7:27918229 C/T cg05786569 chr7:27702416 HIBADH -0.55 -5.22 -0.42 7.2e-7 Gout; TGCT cis rs13102973 0.965 rs13126242 chr4:135860948 T/C cg14419869 chr4:135874104 NA 0.24 4.49 0.37 1.6e-5 Subjective well-being; TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg11883238 chr10:62676418 RHOBTB1 -0.7 -6.8 -0.52 4.03e-10 Follicular lymphoma; TGCT cis rs3540 0.576 rs10152871 chr15:91047469 G/A cg22089800 chr15:90895588 ZNF774 -0.74 -7.48 -0.56 1.17e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg18538332 chr22:24372958 LOC391322 -0.99 -12.8 -0.75 2e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs539096 0.872 rs3791138 chr1:44050027 A/C cg12908607 chr1:44402522 ARTN -0.48 -4.94 -0.41 2.46e-6 Intelligence (multi-trait analysis); TGCT cis rs6684514 1.000 rs2273832 chr1:156233143 A/G cg16558208 chr1:156270281 VHLL 0.48 9.29 0.64 6.47e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg09222892 chr1:25734099 RHCE -0.42 -6.7 -0.52 6.56e-10 Erythrocyte sedimentation rate; TGCT cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg23758822 chr17:41437982 NA 0.78 7.29 0.55 3.14e-11 Menopause (age at onset); TGCT cis rs8038465 0.592 rs899981 chr15:73935329 G/A cg15420318 chr15:73925796 NPTN 0.67 6.96 0.53 1.75e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.830 rs10856936 chr4:99011319 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.53 0.44 1.79e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 1.000 rs3846357 chr4:17635887 A/T cg10189774 chr4:17578691 LAP3 0.62 5.5 0.44 2.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4711350 0.734 rs4713676 chr6:33722098 G/T cg18005901 chr6:33739558 LEMD2 0.5 5.72 0.46 7.42e-8 Schizophrenia; TGCT cis rs42648 0.935 rs2188232 chr7:89958314 A/C cg25739043 chr7:89950458 NA -0.77 -7.39 -0.55 1.93e-11 Homocysteine levels; TGCT cis rs9653442 0.564 rs12712071 chr2:100793876 G/A cg22139774 chr2:100720529 AFF3 -0.35 -5.35 -0.43 4.16e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4786125 0.622 rs1492372 chr16:6920965 C/T cg03623568 chr16:6915990 A2BP1 -0.43 -5.88 -0.47 3.49e-8 Heart rate variability traits (SDNN); TGCT cis rs3806843 0.547 rs246054 chr5:140326159 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs3806843 0.551 rs184996 chr5:140323773 T/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs6728642 1.000 rs17037402 chr2:98014883 C/T cg26665480 chr2:98280029 ACTR1B -0.98 -4.98 -0.41 2.09e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs2836974 0.644 rs2836986 chr21:40702136 A/C cg11890956 chr21:40555474 PSMG1 -0.72 -6.51 -0.5 1.67e-9 Cognitive function; TGCT cis rs5769765 0.624 rs138843 chr22:50183162 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.33 4.66 0.39 7.9e-6 Schizophrenia; TGCT cis rs2797160 1.000 rs1739376 chr6:126012084 C/G cg05901451 chr6:126070800 HEY2 0.59 4.65 0.39 8.23e-6 Endometrial cancer; TGCT cis rs2463822 1.000 rs2513052 chr11:62108248 C/G cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs67311347 1.000 rs73080165 chr3:40533062 G/T cg02782426 chr3:40428986 ENTPD3 0.44 4.74 0.39 5.88e-6 Renal cell carcinoma; TGCT cis rs7599312 0.534 rs7596285 chr2:213406961 G/A cg20637307 chr2:213403960 ERBB4 0.91 11.42 0.72 4.5e-21 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3812049 0.784 rs2617617 chr5:127455008 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.64 5.87 0.47 3.81e-8 Lymphocyte counts;Red cell distribution width; TGCT cis rs79149102 0.579 rs3816261 chr15:75336173 T/A cg09165964 chr15:75287851 SCAMP5 -1.05 -5.56 -0.45 1.59e-7 Lung cancer; TGCT cis rs4563143 0.663 rs2218396 chr19:29236392 C/T cg12667521 chr19:29218732 NA 0.49 5.8 0.46 5.2100000000000003e-08 Methadone dose in opioid dependence; TGCT cis rs7772486 0.875 rs2207785 chr6:146332784 T/G cg05347473 chr6:146136440 FBXO30 0.52 4.98 0.41 2.12e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11578119 0.933 rs12124354 chr1:170415362 G/C cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.66e-8 Male-pattern baldness; TGCT cis rs250677 0.958 rs36070 chr5:148417240 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.81 0.4 4.35e-6 Breast cancer; TGCT cis rs8013055 0.846 rs12893999 chr14:105970842 C/G cg25008857 chr14:105974488 NA 0.28 4.65 0.39 8.41e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs12510870 0.634 rs11728915 chr4:74410237 G/A cg05868023 chr4:75230803 EREG 0.56 5.14 0.42 1.06e-6 Iris color (b* coordinate); TGCT cis rs9303401 0.659 rs12602808 chr17:56698420 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs6088580 0.608 rs2105109 chr20:32971932 A/G cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs4919044 0.808 rs2486680 chr10:94805529 C/T cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs7666738 0.546 rs11727151 chr4:98837353 A/C cg05340658 chr4:99064831 C4orf37 0.54 5.87 0.47 3.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs17486413 chr4:99060544 G/T cg18180107 chr4:99064573 C4orf37 0.57 5.17 0.42 9.06e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs904251 0.828 rs1757174 chr6:37486695 G/A cg08126542 chr6:37504118 NA -0.45 -6.02 -0.48 1.79e-8 Cognitive performance; TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg06873352 chr17:61820015 STRADA 0.59 6.44 0.5 2.37e-9 Prudent dietary pattern; TGCT cis rs9894429 0.646 rs8079963 chr17:79603285 C/T cg18240062 chr17:79603768 NPLOC4 0.56 4.92 0.4 2.67e-6 Eye color traits; TGCT cis rs1865760 0.827 rs9295680 chr6:25944103 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.39 0.5 3.02e-9 Height; TGCT cis rs1401999 1.000 rs4148571 chr3:183720576 A/C cg01324343 chr3:183735012 ABCC5 0.83 11.15 0.71 2.01e-20 Anterior chamber depth; TGCT cis rs394563 0.589 rs1900300 chr6:149641627 T/C cg03678062 chr6:149772716 ZC3H12D 0.37 4.75 0.39 5.59e-6 Dupuytren's disease; TGCT cis rs1008375 0.966 rs2286773 chr4:17616214 C/A cg18681998 chr4:17616180 MED28 1.07 12.29 0.74 3.39e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg26119090 chr2:26468346 HADHA;HADHB -0.97 -7.19 -0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs7829975 0.572 rs7005000 chr8:8796602 A/G cg06636001 chr8:8085503 FLJ10661 -0.73 -6.58 -0.51 1.21e-9 Mood instability; TGCT cis rs6088590 0.561 rs764597 chr20:33161225 C/T cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT trans rs853410 0.516 rs4959915 chr6:4001020 T/C cg13911294 chr9:88951310 ZCCHC6 -0.64 -6.66 -0.51 8.02e-10 Night sleep phenotypes; TGCT cis rs7937682 0.774 rs59921976 chr11:111473088 G/A cg09085632 chr11:111637200 PPP2R1B -1.07 -11.36 -0.71 6.1e-21 Primary sclerosing cholangitis; TGCT cis rs7973719 1.000 rs12828040 chr12:7326541 T/C cg07052231 chr12:7363540 PEX5 0.33 5.08 0.42 1.32e-6 IgG glycosylation; TGCT cis rs672889 0.525 rs558130 chr2:21381689 T/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs6725041 0.819 rs1546718 chr2:213088329 A/G cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs10782582 0.593 rs17585530 chr1:76134990 G/A cg03433033 chr1:76189801 ACADM -0.64 -7.32 -0.55 2.78e-11 Daytime sleep phenotypes; TGCT cis rs4722166 0.695 rs7793125 chr7:22809160 A/G cg26061582 chr7:22766209 IL6 0.48 6.02 0.48 1.8e-8 Lung cancer; TGCT cis rs1971762 0.563 rs7958775 chr12:54077556 T/C cg16917193 chr12:54089295 NA 1.37 17.65 0.85 1.25e-35 Height; TGCT cis rs77741769 0.571 rs61946382 chr12:121344574 A/T cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs7819412 0.594 rs7460507 chr8:10969075 C/T cg21775007 chr8:11205619 TDH -0.5 -5.02 -0.41 1.78e-6 Triglycerides; TGCT cis rs921968 0.509 rs72963905 chr2:219547027 T/G cg02176678 chr2:219576539 TTLL4 -0.5 -6.93 -0.53 2.02e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs11792861 0.926 rs7856626 chr9:111775502 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.5 0.37 1.56e-5 Menarche (age at onset); TGCT cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg00684032 chr4:1343700 KIAA1530 0.21 4.53 0.38 1.36e-5 Obesity-related traits; TGCT cis rs10174077 0.874 rs11892439 chr2:152469858 T/A cg06191203 chr2:152266755 RIF1 -0.7 -6.65 -0.51 8.38e-10 Squamous cell lung carcinoma; TGCT cis rs7394190 0.748 rs3781216 chr10:75522404 G/A cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.48e-6 Incident atrial fibrillation; TGCT cis rs9915657 0.933 rs8075603 chr17:70136833 G/T cg06234051 chr17:70120541 SOX9 -0.25 -4.74 -0.39 5.83e-6 Thyroid hormone levels; TGCT cis rs7172809 0.573 rs13380202 chr15:77659982 G/A cg22256960 chr15:77711686 NA -0.51 -4.79 -0.4 4.65e-6 Glucose homeostasis traits; TGCT cis rs7666738 0.830 rs880470 chr4:98922522 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9926296 0.605 rs886951 chr16:89836865 A/G cg26513180 chr16:89883248 FANCA 1.04 14.53 0.79 1.53e-28 Vitiligo; TGCT cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg18230493 chr5:56204884 C5orf35 -0.69 -6.02 -0.48 1.83e-8 Type 2 diabetes; TGCT cis rs8056742 1.000 rs8056742 chr16:85092748 C/T cg00229868 chr16:85520891 NA -0.31 -4.67 -0.39 7.76e-6 Amyotrophic lateral sclerosis; TGCT cis rs6977940 0.818 rs11770710 chr7:2896123 A/G cg19731401 chr7:2775893 GNA12 0.4 4.81 0.4 4.22e-6 White matter integrity; TGCT cis rs6840360 0.533 rs13145446 chr4:152729035 G/A cg22705602 chr4:152727874 NA 0.34 6.14 0.48 1.02e-8 Intelligence (multi-trait analysis); TGCT cis rs7909074 1.000 rs10751360 chr10:45396971 G/A cg05187965 chr10:45406764 TMEM72 -0.24 -5.23 -0.42 7.12e-7 Mean corpuscular volume; TGCT cis rs3960554 0.529 rs1859795 chr7:75877354 A/G cg19105122 chr7:75896889 SRRM3 0.55 4.59 0.38 1.08e-5 Eotaxin levels; TGCT cis rs933688 0.877 rs10474352 chr5:90732225 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.27 0.6 1.74e-13 Smoking behavior; TGCT cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg08280861 chr8:58055591 NA 0.37 5.03 0.41 1.66e-6 Developmental language disorder (linguistic errors); TGCT cis rs9900497 0.536 rs4646785 chr17:19651902 A/G cg12799818 chr17:19450343 SLC47A1 -0.3 -4.88 -0.4 3.22e-6 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg10819733 chr22:24237672 NA -0.28 -4.59 -0.38 1.06e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.830 rs13108422 chr4:99059267 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.92 0.47 2.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3617 0.573 rs4687682 chr3:52916939 T/C cg10802521 chr3:52805072 NEK4 0.58 6.69 0.51 6.96e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3796352 1.000 rs1346719 chr3:53077372 A/G cg15956490 chr3:53032818 SFMBT1 0.57 6.24 0.49 6.28e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7819412 0.608 rs28417109 chr8:10975081 T/A cg21775007 chr8:11205619 TDH -0.51 -4.91 -0.4 2.87e-6 Triglycerides; TGCT cis rs6076065 0.775 rs761723 chr20:23330720 A/G cg11657817 chr20:23433608 CST11 0.31 5.29 0.43 5.46e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs6665290 0.669 rs3768421 chr1:227177193 G/A cg10327440 chr1:227177885 CDC42BPA -0.9 -14.92 -0.8 1.86e-29 Myeloid white cell count; TGCT cis rs13102973 0.645 rs6535055 chr4:135886101 A/C cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs10504229 0.683 rs73603874 chr8:58108340 G/A cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT trans rs17685 0.753 rs6976532 chr7:75681094 A/G cg19862616 chr7:65841803 NCRNA00174 0.47 8.17 0.59 2.99e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs611744 0.967 rs610452 chr8:109188263 T/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs13064411 0.542 rs4396864 chr3:113212562 C/T cg18753928 chr3:113234510 CCDC52 -0.54 -4.58 -0.38 1.12e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs10032931 0.962 rs1385670 chr4:96456167 T/A cg17031751 chr4:96469067 UNC5C -0.37 -4.82 -0.4 4.16e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs4975709 0.589 rs931508 chr5:1861224 C/G cg07747251 chr5:1868357 NA 0.37 5.06 0.41 1.45e-6 Cardiovascular disease risk factors; TGCT cis rs751728 1.000 rs943477 chr6:33750931 T/C cg13859433 chr6:33739653 LEMD2 -0.39 -7.23 -0.54 4.25e-11 Crohn's disease; TGCT cis rs4665809 0.652 rs6728090 chr2:26524726 C/T cg25036284 chr2:26402008 FAM59B -0.64 -5.06 -0.41 1.44e-6 Gut microbiome composition (summer); TGCT cis rs3806843 0.966 rs12659129 chr5:140147248 T/C cg19875535 chr5:140030758 IK 0.36 6.17 0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6867032 1.000 rs2129472 chr5:2016247 G/A cg26168224 chr5:2018326 NA 0.43 7.96 0.58 9.31e-13 Gut microbiome composition (winter); TGCT cis rs4713118 0.911 rs9461406 chr6:27719764 C/T cg20933634 chr6:27740509 NA -0.35 -5.0 -0.41 1.92e-6 Parkinson's disease; TGCT cis rs832540 0.931 rs2591960 chr5:56238811 A/T cg24531977 chr5:56204891 C5orf35 0.58 5.44 0.44 2.76e-7 Coronary artery disease; TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg02073558 chr3:44770973 ZNF501 0.58 5.68 0.45 8.89e-8 Depressive symptoms; TGCT cis rs9818758 0.607 rs11710247 chr3:49249800 G/T cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg18402987 chr7:1209562 NA 0.39 4.85 0.4 3.57e-6 Longevity;Endometriosis; TGCT cis rs2663905 0.611 rs2663920 chr15:81396404 A/G cg18028999 chr15:81426610 C15orf26 -0.5 -4.7 -0.39 6.77e-6 QT interval (drug interaction); TGCT cis rs72615157 0.634 rs74742883 chr7:99785765 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.64 5.1 0.42 1.26e-6 Lung function (FEV1/FVC); TGCT cis rs7819412 0.669 rs4840549 chr8:10998955 A/G cg21775007 chr8:11205619 TDH -0.55 -5.05 -0.41 1.53e-6 Triglycerides; TGCT cis rs3099143 0.901 rs1813479 chr15:77168646 T/C cg21673338 chr15:77095150 SCAPER 0.52 5.05 0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs17169807 1.000 rs73313138 chr7:33350809 G/A cg06206957 chr7:33080615 NT5C3 0.32 4.44 0.37 1.97e-5 Smooth-surface caries; TGCT cis rs1395 0.922 rs11693052 chr2:27484620 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.69 0.51 6.91e-10 Blood metabolite levels; TGCT cis rs539096 0.715 rs6665014 chr1:44226004 G/T cg12908607 chr1:44402522 ARTN 0.65 6.68 0.51 7.03e-10 Intelligence (multi-trait analysis); TGCT cis rs780096 0.526 rs780106 chr2:27681598 A/C cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT cis rs6089584 0.888 rs2386555 chr20:60612373 C/T cg06108461 chr20:60628389 TAF4 -0.69 -10.56 -0.69 5.46e-19 Body mass index; TGCT cis rs9443645 0.901 rs9352683 chr6:79718795 T/G cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs1372520 0.684 rs356162 chr4:90697157 T/C cg20003494 chr4:90757398 SNCA 0.56 4.46 0.37 1.83e-5 Neuroticism; TGCT cis rs6570726 0.791 rs9399558 chr6:145911730 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9291683 0.620 rs4444830 chr4:10124819 A/G cg11266682 chr4:10021025 SLC2A9 -0.44 -5.24 -0.43 6.65e-7 Bone mineral density; TGCT cis rs12497850 0.931 rs11705888 chr3:48817289 T/C cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs9467773 1.000 rs9393731 chr6:26529374 C/T cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs12681287 0.511 rs7839601 chr8:87503839 G/C cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs12893668 0.703 rs4906336 chr14:104033265 C/G cg26031613 chr14:104095156 KLC1 -0.54 -4.45 -0.37 1.88e-5 Reticulocyte count; TGCT cis rs1018836 0.923 rs7833025 chr8:91568470 G/C cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10088262 0.629 rs6990565 chr8:124785645 C/A cg02993010 chr8:124780839 FAM91A1 -0.63 -4.87 -0.4 3.28e-6 Pancreatic cancer; TGCT cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs7964899 0.750 rs7358578 chr12:14630856 G/A cg10925082 chr12:15114703 ARHGDIB 0.22 4.5 0.37 1.53e-5 Educational attainment (years of education); TGCT cis rs7949030 0.688 rs2849031 chr11:62365665 G/A cg13298116 chr11:62369859 EML3;MTA2 -0.62 -9.24 -0.64 8.81e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8180040 0.691 rs12489211 chr3:47221451 T/A cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT cis rs7681440 0.904 rs7672979 chr4:90767873 A/G cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs7552404 1.000 rs11163924 chr1:76132070 A/C cg22875332 chr1:76189707 ACADM -0.79 -10.12 -0.67 6.33e-18 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs17685 0.753 rs13240967 chr7:75658197 C/T cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs4700695 0.614 rs1864042 chr5:65206722 G/A cg21114390 chr5:65439923 SFRS12 0.67 4.7 0.39 6.91e-6 Facial morphology (factor 19); TGCT cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg07636037 chr3:49044803 WDR6 0.85 8.88 0.62 6.21e-15 Menarche (age at onset); TGCT cis rs35000415 0.688 rs12536719 chr7:128717740 C/T cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT trans rs7819412 0.775 rs2898257 chr8:10935368 A/C cg15556689 chr8:8085844 FLJ10661 -0.84 -8.16 -0.59 3.12e-13 Triglycerides; TGCT cis rs910316 0.967 rs10142770 chr14:75525449 G/A cg23033748 chr14:75592666 NEK9 0.27 4.53 0.38 1.34e-5 Height; TGCT cis rs1801251 1.000 rs6745879 chr2:233590007 A/G cg08000102 chr2:233561755 GIGYF2 0.63 6.53 0.51 1.51e-9 Coronary artery disease; TGCT cis rs7924176 0.564 rs6480727 chr10:76003073 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.45 -4.49 -0.37 1.59e-5 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs9486719 1.000 rs2142653 chr6:96871520 C/A cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT trans rs7726839 1.000 rs7726839 chr5:618586 A/G cg11887960 chr12:57824829 NA 0.85 6.69 0.51 6.9e-10 Obesity-related traits; TGCT cis rs228437 0.586 rs6920152 chr6:134947520 G/T cg09872934 chr6:134495829 SGK1 0.52 4.56 0.38 1.21e-5 Melanoma; TGCT cis rs13191362 1.000 rs55822577 chr6:163069710 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.89 6.39 0.5 3.1e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg15242686 chr22:24348715 GSTTP1 0.41 5.67 0.45 9.33e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs903263 1.000 rs11163911 chr1:84639626 A/G cg09664975 chr1:84543551 PRKACB 0.47 4.48 0.37 1.65e-5 Breast cancer (male); TGCT cis rs4081724 0.565 rs12150908 chr19:33808145 C/A cg18823272 chr19:34111733 CHST8 0.42 4.69 0.39 7.17e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10992471 0.605 rs7872375 chr9:95064843 C/G cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.57 -0.45 1.53e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3820928 0.605 rs13410141 chr2:227805529 A/G cg11843606 chr2:227700838 RHBDD1 -0.51 -4.82 -0.4 4.1e-6 Pulmonary function; TGCT cis rs9916302 0.706 rs3744349 chr17:37414842 C/T cg07936489 chr17:37558343 FBXL20 -0.88 -6.3 -0.49 4.71e-9 Glomerular filtration rate (creatinine); TGCT cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg18305652 chr10:134549665 INPP5A 0.31 5.26 0.43 6.05e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs13326165 0.511 rs1011063 chr3:52506848 A/G cg27565382 chr3:53032988 SFMBT1 0.38 5.15 0.42 9.78e-7 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7542091 0.739 rs10863793 chr1:210037420 G/A cg21951975 chr1:209979733 IRF6 0.53 5.33 0.43 4.43e-7 Monobrow; TGCT cis rs7100689 0.622 rs7082093 chr10:82134954 T/G cg01528321 chr10:82214614 TSPAN14 0.83 7.87 0.58 1.5e-12 Post bronchodilator FEV1; TGCT cis rs1355223 0.583 rs1396881 chr11:34870506 G/T cg11058730 chr11:34937778 PDHX;APIP 0.78 8.67 0.61 2.03e-14 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs61990749 0.597 rs1549119 chr14:78219812 A/T cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg25767906 chr1:53392781 SCP2 -0.55 -6.64 -0.51 8.87e-10 Monocyte count; TGCT cis rs17253792 0.822 rs17253730 chr14:56157911 A/G cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.68 7.22 0.54 4.62e-11 Blood metabolite levels; TGCT cis rs12477438 0.501 rs2632260 chr2:99771590 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.28 0.77 1.43e-25 Chronic sinus infection; TGCT cis rs1475911 0.708 rs56109792 chr21:43520060 A/G cg14562523 chr21:43528734 C21orf128;UMODL1 -0.27 -5.3 -0.43 5.04e-7 IgG glycosylation; TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg21672276 chr3:44754072 ZNF502 -0.54 -6.25 -0.49 6.16e-9 Depressive symptoms; TGCT cis rs881375 0.967 rs876445 chr9:123677102 A/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.99 0.41 2.02e-6 Rheumatoid arthritis; TGCT cis rs3733585 0.673 rs7376948 chr4:9954708 G/A cg11266682 chr4:10021025 SLC2A9 -0.57 -7.44 -0.56 1.45e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11690935 0.959 rs6745143 chr2:172650382 G/A cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg23131131 chr22:24373011 LOC391322 -0.81 -8.71 -0.62 1.56e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4665809 0.878 rs4143538 chr2:26290178 A/C cg04944784 chr2:26401820 FAM59B -0.71 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT cis rs2180341 0.680 rs9388554 chr6:127576234 C/G cg24812749 chr6:127587940 RNF146 0.79 6.6 0.51 1.09e-9 Breast cancer; TGCT cis rs13217239 0.646 rs6937880 chr6:27000236 C/T cg15659132 chr6:26577336 NA 0.54 5.44 0.44 2.78e-7 Schizophrenia; TGCT trans rs3780486 0.846 rs10813948 chr9:33121570 G/A cg04842962 chr6:43655489 MRPS18A 1.23 15.36 0.81 1.81e-30 IgG glycosylation; TGCT cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs10048683 chr2:26320519 C/T cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs10193935 0.901 rs222464 chr2:42643889 C/T cg27598129 chr2:42591480 NA -0.37 -5.32 -0.43 4.69e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7914558 0.966 rs3977751 chr10:104920232 A/G cg04362960 chr10:104952993 NT5C2 0.62 5.48 0.44 2.32e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17076896 0.786 rs61956088 chr13:19937911 G/A cg00777926 chr13:20807375 GJB6 -0.41 -4.82 -0.4 4.03e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs6714710 0.603 rs11123974 chr2:98605982 A/G cg26665480 chr2:98280029 ACTR1B 0.63 6.03 0.48 1.75e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs4664308 1.000 rs1511218 chr2:160906390 T/C cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs875971 1.000 rs6460296 chr7:65895139 C/T cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs7249142 0.562 rs10417796 chr19:19287072 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.33 -4.51 -0.38 1.5e-5 IgG glycosylation; TGCT trans rs2469997 1.000 rs2447183 chr8:120352978 A/G cg01792902 chr3:178864926 PIK3CA 0.78 6.66 0.51 7.93e-10 Hypertension (SNP x SNP interaction); TGCT cis rs1784581 1.000 rs1618170 chr6:162400337 C/T cg17173639 chr6:162384350 PARK2 -0.5 -9.17 -0.64 1.26e-15 Itch intensity from mosquito bite; TGCT cis rs1865760 1.000 rs2071298 chr6:25914901 G/A cg16482183 chr6:26056742 HIST1H1C 0.52 4.6 0.38 1.04e-5 Height; TGCT cis rs2404602 0.583 rs3759853 chr15:76587777 C/T cg22467129 chr15:76604101 ETFA -0.61 -7.93 -0.58 1.07e-12 Blood metabolite levels; TGCT cis rs611744 0.870 rs613261 chr8:109165949 A/G cg21045802 chr8:109455806 TTC35 0.69 6.06 0.48 1.51e-8 Dupuytren's disease; TGCT cis rs6933660 0.745 rs6557138 chr6:151732017 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.62 0.38 9.63e-6 Menarche (age at onset); TGCT cis rs9611565 0.512 rs5996063 chr22:42168767 G/A cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs2857078 0.654 rs4793083 chr17:42312973 C/T cg19774624 chr17:42201019 HDAC5 0.75 7.6 0.56 6.45e-12 Red cell distribution width;Reticulocyte count; TGCT cis rs3617 0.625 rs7620690 chr3:52891707 A/G cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6.08e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs76419734 0.510 rs2553456 chr4:106751028 T/C cg24545054 chr4:106630052 GSTCD;INTS12 -0.7 -4.52 -0.38 1.43e-5 Post bronchodilator FEV1; TGCT cis rs1018836 0.595 rs2223010 chr8:91480068 A/G cg16814680 chr8:91681699 NA -0.81 -8.27 -0.6 1.8e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7226408 0.948 rs11665609 chr18:34387348 C/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs782590 0.935 rs6739513 chr2:55749902 G/A cg03859395 chr2:55845619 SMEK2 0.93 11.51 0.72 2.7e-21 Metabolic syndrome; TGCT cis rs3008870 1.000 rs12039172 chr1:67447450 A/G cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs6500602 0.627 rs3848372 chr16:4587875 C/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.34 4.92 0.4 2.68e-6 Schizophrenia; TGCT cis rs2486012 1.000 rs2428954 chr1:44442930 A/G cg12908607 chr1:44402522 ARTN 0.67 5.9 0.47 3.17e-8 Intelligence (multi-trait analysis); TGCT cis rs12368653 0.583 rs7952989 chr12:58095989 T/C cg12615879 chr12:58013172 SLC26A10 0.49 5.9 0.47 3.27e-8 Multiple sclerosis; TGCT cis rs7188861 0.603 rs2113260 chr16:11455993 C/T cg00044050 chr16:11439710 C16orf75 0.61 5.43 0.44 2.89e-7 HDL cholesterol; TGCT cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg17971929 chr21:40555470 PSMG1 -0.7 -6.5 -0.5 1.8e-9 Cognitive function; TGCT cis rs1997103 1.000 rs2177804 chr7:55410302 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2836950 0.501 rs1474490 chr21:40716136 C/A cg11890956 chr21:40555474 PSMG1 -0.6 -5.49 -0.44 2.2e-7 Menarche (age at onset); TGCT cis rs9807989 0.801 rs72823663 chr2:102968738 G/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg01448562 chr3:133502909 NA -0.34 -6.9 -0.53 2.37e-10 Iron status biomarkers; TGCT cis rs473651 0.904 rs508274 chr2:239337723 G/A cg18131467 chr2:239335373 ASB1 1.03 15.25 0.81 3.21e-30 Multiple system atrophy; TGCT cis rs10782582 0.586 rs11161902 chr1:76392498 C/G cg03433033 chr1:76189801 ACADM -0.49 -4.81 -0.4 4.29e-6 Daytime sleep phenotypes; TGCT cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.962 rs9679865 chr20:61666132 C/G cg08564027 chr20:61660810 NA 0.37 6.64 0.51 8.85e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs8033133 0.560 rs12441340 chr15:25323964 G/T cg14481604 chr15:25334117 SNORD116-22 -0.21 -4.54 -0.38 1.33e-5 Blood osmolality (transformed sodium); TGCT cis rs28408315 0.958 rs3129 chr15:79214215 A/G cg15822222 chr15:79164806 MORF4L1 -0.49 -5.42 -0.44 2.95e-7 Lung cancer;Lung cancer in ever smokers;Lung adenocarcinoma; TGCT cis rs3806843 0.576 rs246002 chr5:140341104 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs7666738 1.000 rs7666738 chr4:98968077 C/T cg05340658 chr4:99064831 C4orf37 0.49 4.87 0.4 3.4e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7824557 0.510 rs4841524 chr8:11243126 C/G cg27411982 chr8:10470053 RP1L1 -0.22 -4.84 -0.4 3.74e-6 Retinal vascular caliber; TGCT cis rs2617583 0.509 rs2937650 chr5:1458018 C/T cg13982541 chr5:1466431 LPCAT1 -0.2 -4.86 -0.4 3.53e-6 Breast cancer; TGCT cis rs2795502 0.882 rs3123754 chr10:43339011 G/A cg20628663 chr10:43360327 NA -0.44 -6.37 -0.5 3.4e-9 Blood protein levels; TGCT cis rs7178572 0.568 rs7166927 chr15:77673459 A/G cg15453836 chr15:77711506 NA 0.42 4.78 0.39 4.92e-6 Type 2 diabetes; TGCT cis rs1669338 0.588 rs7629889 chr3:3187643 C/T cg16797762 chr3:3221439 CRBN -0.86 -5.26 -0.43 6.24e-7 White matter integrity; TGCT cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -4.82 -0.4 4.19e-6 Developmental language disorder (linguistic errors); TGCT cis rs1372520 0.935 rs1442152 chr4:90775649 C/A cg01966878 chr4:90757139 SNCA -0.3 -4.71 -0.39 6.55e-6 Neuroticism; TGCT cis rs3008870 1.000 rs58680688 chr1:67443751 C/G cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs78487399 0.710 rs6544665 chr2:43729212 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.82 -0.4 4.03e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1552244 1.000 rs1552244 chr3:10135577 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs2594989 0.895 rs2442789 chr3:11540188 C/T cg26283222 chr3:11613257 VGLL4 -0.22 -4.69 -0.39 7.11e-6 Circulating chemerin levels; TGCT trans rs4332037 0.575 rs55952733 chr7:2070680 G/A cg25206134 chr2:45395956 NA 0.97 7.42 0.55 1.6e-11 Bipolar disorder; TGCT cis rs7666738 0.791 rs34152299 chr4:98929862 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9311474 1.000 rs1060330 chr3:52288945 T/C cg10802521 chr3:52805072 NEK4 -0.56 -6.25 -0.49 6.16e-9 Electroencephalogram traits; TGCT cis rs12220238 0.841 rs11000952 chr10:76037336 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.88 5.98 0.47 2.22e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7617480 0.648 rs9859473 chr3:48837182 A/G cg06212747 chr3:49208901 KLHDC8B 0.58 4.58 0.38 1.1e-5 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs6754311 0.731 rs2164210 chr2:136580287 T/C cg07169764 chr2:136633963 MCM6 -0.61 -5.61 -0.45 1.25e-7 Mosquito bite size; TGCT cis rs7937682 0.558 rs7113067 chr11:111692182 G/A cg09085632 chr11:111637200 PPP2R1B 0.81 6.94 0.53 1.92e-10 Primary sclerosing cholangitis; TGCT cis rs2702888 0.622 rs2702933 chr8:6760142 A/G cg26795848 chr8:6756730 NA -0.28 -5.96 -0.47 2.39e-8 Blood pressure; TGCT cis rs6693567 0.565 rs7513182 chr1:150442612 A/G cg09579323 chr1:150459698 TARS2 -0.52 -4.62 -0.38 9.55e-6 Migraine; TGCT cis rs2692947 0.770 rs62153678 chr2:96558346 C/T cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs11098499 0.863 rs11731756 chr4:120478696 T/G cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs42648 0.935 rs42621 chr7:89956484 A/G cg25739043 chr7:89950458 NA -0.75 -7.62 -0.56 5.63e-12 Homocysteine levels; TGCT cis rs1023500 0.573 rs4822088 chr22:42470589 G/C cg05082376 chr22:42548792 NA -0.23 -5.43 -0.44 2.83e-7 Schizophrenia; TGCT cis rs4665809 1.000 rs6739061 chr2:26256147 C/T cg04944784 chr2:26401820 FAM59B -0.67 -5.98 -0.47 2.23e-8 Gut microbiome composition (summer); TGCT cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg09222892 chr1:25734099 RHCE 0.42 6.97 0.53 1.68e-10 Erythrocyte sedimentation rate; TGCT cis rs7193541 0.825 rs4411525 chr16:74595502 A/C cg01733217 chr16:74700730 RFWD3 0.76 6.89 0.53 2.45e-10 Multiple myeloma; TGCT cis rs35883536 0.647 rs7535762 chr1:101047534 A/G cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs9810089 0.900 rs480162 chr3:136068695 A/T cg12473912 chr3:136751656 NA 0.35 5.04 0.41 1.59e-6 Gestational age at birth (child effect); TGCT cis rs6688613 0.729 rs41269702 chr1:166958937 G/T cg07049167 chr1:166818506 POGK 0.23 4.72 0.39 6.21e-6 Refractive astigmatism; TGCT cis rs7394190 0.630 rs4746150 chr10:75565935 A/G cg07699608 chr10:75541558 CHCHD1 0.8 4.77 0.39 5.18e-6 Incident atrial fibrillation; TGCT cis rs28493229 0.522 rs17713068 chr19:41270055 A/C cg23743927 chr19:41304969 EGLN2 -0.74 -4.67 -0.39 7.7e-6 Kawasaki disease; TGCT cis rs12950390 0.853 rs11079791 chr17:45859099 C/T cg06532163 chr17:45867833 NA 0.37 5.96 0.47 2.45e-8 IgG glycosylation; TGCT cis rs7729723 0.533 rs219278 chr5:137834091 G/A cg19169342 chr5:137827400 NA 0.33 4.53 0.38 1.37e-5 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs7666738 0.830 rs34671152 chr4:98978177 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs916888 0.821 rs415430 chr17:44859144 C/T cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1670533 1.000 rs6822863 chr4:1055606 G/A cg27284194 chr4:1044797 NA 0.68 5.88 0.47 3.56e-8 Recombination rate (females); TGCT cis rs11209185 0.509 rs12142271 chr1:68446837 A/G cg22082780 chr1:68452167 NA 0.31 4.84 0.4 3.86e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs4819052 0.851 rs10470247 chr21:46659018 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.62 5.22 0.42 7.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs42648 0.837 rs10262472 chr7:89900383 T/C cg25739043 chr7:89950458 NA -0.74 -7.33 -0.55 2.64e-11 Homocysteine levels; TGCT cis rs6988636 0.818 rs1713733 chr8:124199458 A/G cg22384356 chr8:124195192 FAM83A 0.34 4.44 0.37 1.98e-5 Urinary uromodulin levels; TGCT cis rs1011108 0.518 rs935172 chr2:26804247 A/G cg18742855 chr2:26800399 C2orf70 -0.23 -5.21 -0.42 7.7300000000000005e-07 Periodontal microbiota; TGCT cis rs514406 0.861 rs11206026 chr1:53281708 G/A cg08736216 chr1:53307985 ZYG11A -0.23 -4.5 -0.37 1.55e-5 Monocyte count; TGCT cis rs939574 1.000 rs79013471 chr2:220096122 C/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.06 6.52 0.51 1.6e-9 Platelet distribution width; TGCT cis rs9928842 0.941 rs8057145 chr16:75256251 A/G cg09066997 chr16:75300724 BCAR1 0.25 4.58 0.38 1.14e-5 Alcoholic chronic pancreatitis; TGCT cis rs2832191 0.765 rs2832162 chr21:30461808 G/A cg24692254 chr21:30365293 RNF160 0.91 9.85 0.66 2.96e-17 Dental caries; TGCT cis rs806215 0.526 rs806174 chr7:127291072 C/A cg11539674 chr7:127291444 SND1 0.38 4.72 0.39 6.23e-6 Type 2 diabetes; TGCT cis rs5769765 1.000 rs738711 chr22:50282603 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.07 -0.48 1.46e-8 Schizophrenia; TGCT cis rs7617773 0.539 rs1471217 chr3:48384895 A/C cg11946769 chr3:48343235 NME6 0.57 4.83 0.4 4.01e-6 Coronary artery disease; TGCT cis rs854765 0.547 rs2955359 chr17:17946730 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs4268898 0.722 rs35520052 chr2:24415277 C/T cg05570707 chr2:24270316 C2orf44 0.47 4.62 0.38 9.59e-6 Asthma; TGCT cis rs8177253 0.965 rs8177245 chr3:133479230 A/G cg11941060 chr3:133502564 NA -0.29 -6.15 -0.48 9.6e-9 Iron status biomarkers; TGCT cis rs62244186 0.659 rs9819766 chr3:44520980 G/C cg10263370 chr3:44754102 ZNF502 -0.38 -4.45 -0.37 1.86e-5 Depressive symptoms; TGCT cis rs2832191 0.647 rs11170 chr21:30378090 C/T cg24692254 chr21:30365293 RNF160 0.9 10.54 0.69 6.03e-19 Dental caries; TGCT cis rs12477438 1.000 rs73963398 chr2:99887025 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.8 -6.4 -0.5 2.92e-9 Chronic sinus infection; TGCT cis rs6714788 0.503 rs11681737 chr2:100679024 T/C cg22139774 chr2:100720529 AFF3 -0.41 -5.99 -0.47 2.16e-8 Intelligence (multi-trait analysis); TGCT cis rs11711311 1.000 rs9855613 chr3:113448455 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.71 -6.58 -0.51 1.19e-9 IgG glycosylation; TGCT cis rs2073300 1.000 rs115730610 chr20:23442621 G/A cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs3733585 0.682 rs13124563 chr4:9927553 A/G cg00071950 chr4:10020882 SLC2A9 0.61 7.3 0.55 3.11e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4819052 0.851 rs9974891 chr21:46680767 T/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.06 0.54 1.07e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10782582 0.569 rs4549990 chr1:76125075 A/G cg03433033 chr1:76189801 ACADM -0.63 -7.27 -0.55 3.6e-11 Daytime sleep phenotypes; TGCT cis rs2066819 1.000 rs57870697 chr12:56752874 A/G cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs9420907 0.579 rs34547036 chr10:105637026 C/T cg26719024 chr10:105156444 PDCD11;USMG5 -0.85 -4.66 -0.39 8.08e-6 Telomere length; TGCT cis rs3820068 0.532 rs78917815 chr1:15920821 A/G cg05660106 chr1:15850417 CASP9 0.84 8.27 0.6 1.8e-13 Systolic blood pressure; TGCT cis rs13256369 0.950 rs13270006 chr8:8574197 C/A cg06671706 chr8:8559999 CLDN23 0.35 4.62 0.38 9.35e-6 Obesity-related traits; TGCT cis rs137603 0.966 rs137616 chr22:39703883 A/G cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -5.12 -0.42 1.15e-6 Primary biliary cholangitis; TGCT cis rs7681423 1.000 rs2066854 chr4:155535181 T/A cg20735720 chr4:155535218 FGG -0.46 -6.71 -0.52 6.24e-10 Fibrinogen; TGCT cis rs11190604 0.943 rs3750631 chr10:102279294 A/G cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3125734 0.633 rs6479791 chr10:63980341 T/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.52 -0.38 1.4e-5 Rheumatoid arthritis; TGCT cis rs2562456 0.917 rs2562468 chr19:21714850 G/A cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg10819733 chr22:24237672 NA -0.28 -4.55 -0.38 1.26e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2637266 1.000 rs12252604 chr10:78352591 T/C cg18941641 chr10:78392320 NA 0.41 5.05 0.41 1.56e-6 Pulmonary function; TGCT cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs9341808 0.667 rs2490251 chr6:80895164 A/G cg08355045 chr6:80787529 NA 0.3 5.09 0.42 1.27e-6 Sitting height ratio; TGCT cis rs11671005 0.735 rs1122955 chr19:58946203 C/T cg13877915 chr19:58951672 ZNF132 0.63 5.0 0.41 1.95e-6 Mean platelet volume; TGCT cis rs6430585 0.583 rs78364332 chr2:136640101 T/C cg07169764 chr2:136633963 MCM6 1.23 11.98 0.73 1.9e-22 Corneal structure; TGCT cis rs2742417 0.587 rs2742375 chr3:45784602 G/A cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2594989 0.895 rs2606759 chr3:11349494 T/C cg00170343 chr3:11313890 ATG7 0.61 4.58 0.38 1.11e-5 Circulating chemerin levels; TGCT cis rs3796619 1.000 rs11939380 chr4:1086871 C/T cg27284194 chr4:1044797 NA -0.46 -4.53 -0.38 1.36e-5 Recombination rate (males); TGCT cis rs4565302 0.539 rs62397056 chr6:38445982 G/A cg08650320 chr6:39083032 C6orf64 0.72 4.76 0.39 5.27e-6 Mammographic density; TGCT cis rs7666738 0.927 rs6832373 chr4:99051967 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.59 0.56 6.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs3796352 1.000 rs9874517 chr3:53128371 A/G cg07884673 chr3:53033167 SFMBT1 0.49 5.11 0.42 1.16e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2237234 0.813 rs34565965 chr6:26350810 T/A cg16898833 chr6:26189333 HIST1H4D 0.65 4.46 0.37 1.79e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7267979 0.844 rs6076343 chr20:25376663 C/T cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs67311347 0.866 rs11712426 chr3:40330322 G/A cg13683864 chr3:40499215 RPL14 -0.89 -8.61 -0.61 2.81e-14 Renal cell carcinoma; TGCT cis rs12908161 1.000 rs62019464 chr15:85294469 T/A cg11189052 chr15:85197271 WDR73 0.71 5.83 0.46 4.47e-8 Schizophrenia; TGCT cis rs2013441 1.000 rs2703778 chr17:20138900 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs1062177 0.724 rs2915828 chr5:151118121 G/A cg00977110 chr5:151150581 G3BP1 -0.4 -4.67 -0.39 7.7e-6 Preschool internalizing problems; TGCT cis rs3796352 1.000 rs35174175 chr3:53041509 T/C cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs112217694 1.000 rs55703794 chr4:104650272 G/A cg24090629 chr4:104641072 TACR3 -1.0 -5.19 -0.42 8.44e-7 Menarche (age at onset); TGCT cis rs797680 0.856 rs12124011 chr1:93652544 C/A cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.89e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs986417 1.000 rs12895784 chr14:60980116 G/T cg27398547 chr14:60952738 C14orf39 1.48 11.21 0.71 1.46e-20 Gut microbiota (bacterial taxa); TGCT cis rs9357506 0.967 rs9395173 chr6:46311493 T/C cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs11098499 0.865 rs10213221 chr4:120255926 G/A cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Corneal astigmatism; TGCT cis rs921968 0.643 rs3845836 chr2:219504955 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.16 0.48 9.35e-9 Mean corpuscular hemoglobin concentration; TGCT trans rs6089829 0.851 rs10854168 chr20:61669550 A/G cg23505145 chr19:12996616 KLF1 0.96 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs9534288 0.552 rs2840241 chr13:46658903 T/G cg15192986 chr13:46630673 CPB2 -0.53 -6.39 -0.5 3.01e-9 Blood protein levels; TGCT cis rs7666738 0.800 rs2865988 chr4:99067807 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs1976559 chr1:154879788 A/T cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs912057 0.671 rs1294427 chr6:6744546 T/G cg06612196 chr6:6737390 NA 0.48 6.95 0.53 1.82e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9928842 0.664 rs8053265 chr16:75221851 C/T cg09066997 chr16:75300724 BCAR1 0.24 4.56 0.38 1.22e-5 Alcoholic chronic pancreatitis; TGCT cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg13409248 chr3:40428643 ENTPD3 0.55 4.46 0.37 1.78e-5 Renal cell carcinoma; TGCT cis rs8177253 1.000 rs8177272 chr3:133482870 C/T cg20276088 chr3:133502917 NA -0.24 -4.98 -0.41 2.04e-6 Iron status biomarkers; TGCT cis rs7267979 0.966 rs2261784 chr20:25262396 G/C cg16686733 chr20:25566563 NINL 0.61 6.1 0.48 1.23e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12681287 0.547 rs13261956 chr8:87478765 G/A cg27223183 chr8:87520930 FAM82B -0.89 -6.34 -0.49 3.84e-9 Caudate activity during reward; TGCT cis rs4919694 1.000 rs11191545 chr10:104829793 C/T cg04362960 chr10:104952993 NT5C2 1.01 6.66 0.51 7.9e-10 Arsenic metabolism; TGCT cis rs4631830 0.737 rs7071471 chr10:51503335 C/T cg10326726 chr10:51549505 MSMB 0.27 5.24 0.43 6.7e-7 Prostate-specific antigen levels; TGCT cis rs9303401 0.615 rs35288118 chr17:56600748 A/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs1629083 0.935 rs1793151 chr11:118126920 C/T cg16594165 chr11:118135105 MPZL2 -0.33 -4.62 -0.38 9.51e-6 Lung cancer; TGCT cis rs2295359 0.892 rs11209005 chr1:67618678 A/G cg12940439 chr1:67600707 NA 0.62 6.45 0.5 2.29e-9 Psoriasis; TGCT cis rs9611565 0.506 rs7364221 chr22:41650190 C/A cg06634786 chr22:41940651 POLR3H -0.57 -5.15 -0.42 1.01e-6 Vitiligo; TGCT cis rs9952991 0.566 rs7234029 chr18:12877060 C/T cg23544223 chr18:12777786 NA 0.54 4.86 0.4 3.42e-6 Inflammatory skin disease; TGCT cis rs4665809 1.000 rs6546726 chr2:26275116 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.45 -0.5 2.32e-9 Gut microbiome composition (summer); TGCT cis rs4566357 0.615 rs2272200 chr2:227912331 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -5.25 -0.43 6.53e-7 Coronary artery disease; TGCT cis rs9311474 0.713 rs352165 chr3:52242902 A/G cg07507251 chr3:52567010 NT5DC2 0.43 5.63 0.45 1.16e-7 Electroencephalogram traits; TGCT cis rs10851411 0.826 rs2617237 chr15:42765624 C/T cg12711755 chr15:41779622 NA -0.2 -4.91 -0.4 2.86e-6 Glucose homeostasis traits; TGCT cis rs34734847 0.787 rs695949 chr12:121149736 A/G cg21892295 chr12:121157589 UNC119B -0.2 -4.72 -0.39 6.18e-6 Mean corpuscular volume; TGCT cis rs4072705 0.615 rs7869829 chr9:127247177 G/A cg13476313 chr9:127244764 NR5A1 -0.29 -4.91 -0.4 2.86e-6 Menarche (age at onset); TGCT cis rs9486715 0.790 rs2971602 chr6:97022468 C/T cg18709589 chr6:96969512 KIAA0776 -0.87 -8.46 -0.61 6.16e-14 Headache; TGCT trans rs28735056 0.933 rs499260 chr18:77589689 G/A cg05926928 chr17:57297772 GDPD1 -0.71 -7.64 -0.57 5.03e-12 Schizophrenia; TGCT cis rs709400 0.691 rs12888077 chr14:103872553 G/T cg26031613 chr14:104095156 KLC1 -0.8 -8.72 -0.62 1.49e-14 Body mass index; TGCT cis rs11690935 0.959 rs10184866 chr2:172608956 T/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.5 -0.75 1.05e-23 Schizophrenia; TGCT cis rs2688608 0.620 rs7098444 chr10:75580042 C/T cg23231163 chr10:75533350 FUT11 -0.27 -4.64 -0.38 8.56e-6 Inflammatory bowel disease; TGCT cis rs6906287 0.625 rs9320648 chr6:118690014 A/C cg21191810 chr6:118973309 C6orf204 0.27 4.58 0.38 1.11e-5 Electrocardiographic conduction measures; TGCT cis rs9419702 0.538 rs9419625 chr10:133534954 T/G cg04492858 chr10:133558786 NA 0.57 6.07 0.48 1.44e-8 Survival in rectal cancer; TGCT cis rs6430585 0.583 rs3769012 chr2:136556480 C/T cg07169764 chr2:136633963 MCM6 1.23 12.14 0.74 8.06e-23 Corneal structure; TGCT cis rs9952991 0.941 rs45450798 chr18:12792940 C/G cg23544223 chr18:12777786 NA -0.6 -5.3 -0.43 5.22e-7 Inflammatory skin disease; TGCT cis rs7208859 0.623 rs8067338 chr17:29102345 T/C cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs739496 0.947 rs10849949 chr12:111893537 C/T cg10833066 chr12:111807467 FAM109A -0.35 -5.4 -0.44 3.2e-7 Platelet count; TGCT cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg06481639 chr22:41940642 POLR3H -0.62 -5.61 -0.45 1.27e-7 Vitiligo; TGCT cis rs6964587 0.967 rs34574955 chr7:91847550 A/C cg17063962 chr7:91808500 NA 0.91 9.8 0.66 3.82e-17 Breast cancer; TGCT cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.12e-11 Intelligence (multi-trait analysis); TGCT cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg07138768 chr7:917805 C7orf20 0.45 5.85 0.47 4.01e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs3809566 0.963 rs12148057 chr15:63331509 A/T cg05507819 chr15:63340323 TPM1 0.48 4.52 0.38 1.4e-5 Platelet count; TGCT cis rs4631830 0.900 rs10763546 chr10:51536399 C/G cg10326726 chr10:51549505 MSMB -0.25 -5.27 -0.43 5.89e-7 Prostate-specific antigen levels; TGCT cis rs10114408 0.837 rs10115198 chr9:96632030 A/G cg13679303 chr9:96623674 NA -0.35 -4.58 -0.38 1.1e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1532993 0.518 rs3843445 chr4:98611576 C/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6598955 0.670 rs4659366 chr1:26542572 G/A cg04990556 chr1:26633338 UBXN11 -0.89 -11.3 -0.71 8.55e-21 Obesity-related traits; TGCT cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs72781680 0.821 rs1022346 chr2:24127849 T/C cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs789859 1.000 rs789862 chr3:194404522 C/T cg21106136 chr3:194405973 FAM43A 0.38 5.42 0.44 3e-7 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs7302981 0.900 rs836179 chr12:50503082 A/G cg23855989 chr12:50355821 AQP5 0.3 4.44 0.37 2e-5 Systolic blood pressure; TGCT cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg02073558 chr3:44770973 ZNF501 0.62 6.04 0.48 1.66e-8 Depressive symptoms; TGCT cis rs2982552 0.901 rs2982561 chr6:152052652 C/T cg22157087 chr6:152012887 ESR1 0.19 4.67 0.39 7.62e-6 Bone properties (heel); TGCT cis rs8103278 0.507 rs4802276 chr19:46260748 T/C cg11657440 chr19:46296263 DMWD 0.73 7.76 0.57 2.78e-12 Coronary artery disease; TGCT cis rs4689388 0.853 rs13114527 chr4:6294655 T/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs8051431 0.876 rs7205914 chr16:72018901 A/G cg06353428 chr16:71660113 MARVELD3 0.57 4.54 0.38 1.31e-5 LDL cholesterol levels; TGCT cis rs3749237 0.595 rs4855877 chr3:49448527 T/C cg03060546 chr3:49711283 APEH 0.77 9.0 0.63 3.2e-15 Resting heart rate; TGCT cis rs4722166 0.597 rs1554606 chr7:22768707 T/G cg05265849 chr7:22767390 IL6 0.23 4.57 0.38 1.18e-5 Lung cancer; TGCT cis rs9611565 0.546 rs2092274 chr22:42123737 A/G cg06634786 chr22:41940651 POLR3H 0.89 9.09 0.63 1.96e-15 Vitiligo; TGCT cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs12145833 0.920 rs12354170 chr1:243457776 G/T cg15780870 chr12:130953802 RIMBP2 0.48 6.73 0.52 5.57e-10 Obesity (early onset extreme); TGCT cis rs13256369 0.851 rs13267036 chr8:8566685 G/A cg18904891 chr8:8559673 CLDN23 0.58 5.3 0.43 5.11e-7 Obesity-related traits; TGCT cis rs4517514 0.509 rs10830411 chr11:89865532 A/G cg05041596 chr11:89867385 NAALAD2 0.52 4.56 0.38 1.22e-5 Trans fatty acid levels; TGCT cis rs9303401 0.659 rs17822837 chr17:56737838 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.64 6.0 0.47 2.05e-8 Cognitive test performance; TGCT cis rs7000551 0.751 rs1116084 chr8:22395309 C/T cg12081754 chr8:22256438 SLC39A14 0.28 4.54 0.38 1.34e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs78487399 0.808 rs17030889 chr2:43702829 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4689388 0.853 rs13108780 chr4:6294630 A/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10256972 0.721 rs10435145 chr7:1065988 C/T cg23708337 chr7:1209742 NA 0.33 4.47 0.37 1.77e-5 Longevity;Endometriosis; TGCT cis rs2742417 1.000 rs2742431 chr3:45737121 C/G cg04837898 chr3:45731254 SACM1L 0.55 5.68 0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs10206020 0.885 rs11886082 chr2:1576683 T/C cg01028140 chr2:1542097 TPO -0.29 -4.56 -0.38 1.22e-5 IgG glycosylation; TGCT trans rs8073060 0.586 rs11080356 chr17:33895309 T/C cg19694781 chr19:47549865 TMEM160 0.61 13.83 0.78 6.76e-27 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7975161 0.832 rs11111955 chr12:104650735 T/C cg25273343 chr12:104657179 TXNRD1 -0.36 -5.29 -0.43 5.32e-7 Toenail selenium levels; TGCT cis rs244731 0.959 rs9313752 chr5:176645435 G/T cg17509989 chr5:176798049 RGS14 -0.63 -7.44 -0.56 1.44e-11 Urate levels in lean individuals; TGCT cis rs7726839 0.561 rs72703058 chr5:584519 G/A cg09021430 chr5:549028 NA -0.37 -5.23 -0.42 7.12e-7 Obesity-related traits; TGCT cis rs74233809 1.000 rs732998 chr10:104897901 C/T cg05855489 chr10:104503620 C10orf26 -0.82 -4.44 -0.37 1.97e-5 Birth weight; TGCT cis rs981844 0.775 rs10517580 chr4:154744128 T/G cg14289246 chr4:154710475 SFRP2 1.01 8.8 0.62 9.72e-15 Response to statins (LDL cholesterol change); TGCT cis rs6089829 0.926 rs7273917 chr20:61665975 G/A cg08045932 chr20:61659980 NA 0.49 9.18 0.64 1.24e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs2952156 0.684 rs931992 chr17:37821435 G/T cg00129232 chr17:37814104 STARD3 -0.22 -4.48 -0.37 1.68e-5 Asthma; TGCT cis rs1371867 0.846 rs1660324 chr8:101281271 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.5 -0.37 1.53e-5 Atrioventricular conduction; TGCT cis rs2153535 0.542 rs9393012 chr6:8439809 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs7611238 0.560 rs7618499 chr3:195059315 A/G cg27323046 chr3:195102265 ACAP2 0.35 4.75 0.39 5.5e-6 Body mass index; TGCT trans rs931812 0.895 rs13251731 chr8:101902528 C/G cg20993868 chr7:22813445 NA 0.4 8.85 0.62 7.57e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg09222892 chr1:25734099 RHCE 0.42 7.15 0.54 6.72e-11 Erythrocyte sedimentation rate; TGCT cis rs4704846 1.000 rs919745 chr5:156531279 A/G cg12943317 chr5:156479607 HAVCR1 0.32 4.56 0.38 1.23e-5 Blood protein levels; TGCT cis rs73198271 0.722 rs11785741 chr8:8605512 A/G cg06671706 chr8:8559999 CLDN23 -0.36 -4.52 -0.38 1.43e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1218582 0.774 rs2335409 chr1:154916106 G/A cg16680214 chr1:154839983 KCNN3 -0.42 -9.27 -0.64 7.16e-16 Prostate cancer; TGCT cis rs4711336 1.000 rs2229642 chr6:33659472 C/G cg14003231 chr6:33640908 ITPR3 0.28 4.52 0.38 1.41e-5 Height; TGCT cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs7586879 0.639 rs3903070 chr2:25123463 C/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs459571 1.000 rs467387 chr9:136907005 G/A cg13789015 chr9:136890014 NCRNA00094 0.41 7.62 0.56 5.63e-12 Platelet distribution width; TGCT cis rs10782582 0.569 rs4549990 chr1:76125075 A/G cg10523679 chr1:76189770 ACADM -0.7 -7.51 -0.56 9.94e-12 Daytime sleep phenotypes; TGCT cis rs35934224 0.783 rs7290770 chr22:19861161 C/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.06 -0.41 1.47e-6 Glaucoma (primary open-angle); TGCT cis rs801193 0.935 rs2659916 chr7:66151352 C/G cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs55883249 1.000 rs17453752 chr2:9766171 C/T cg23886495 chr2:9695866 ADAM17 -0.76 -4.8 -0.4 4.56e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs2228479 1.000 rs12596492 chr16:89957169 T/G cg06558623 chr16:89946397 TCF25 0.57 6.52 0.51 1.62e-9 Skin colour saturation; TGCT cis rs1062177 1.000 rs1062177 chr5:151184701 C/T cg00977110 chr5:151150581 G3BP1 0.4 4.48 0.37 1.64e-5 Preschool internalizing problems; TGCT cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9325144 0.560 rs1843910 chr12:38677408 T/C cg26384229 chr12:38710491 ALG10B -0.69 -6.57 -0.51 1.26e-9 Morning vs. evening chronotype; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.78 7.41 0.55 1.68e-11 Prudent dietary pattern; TGCT cis rs9611565 0.571 rs7364123 chr22:42216326 A/G cg17554472 chr22:41940697 POLR3H -0.45 -4.67 -0.39 7.66e-6 Vitiligo; TGCT cis rs7085104 0.513 rs619824 chr10:104581288 G/T cg04362960 chr10:104952993 NT5C2 0.52 4.61 0.38 9.85e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg06238570 chr21:40685208 BRWD1 0.59 5.25 0.43 6.37e-7 Cognitive function; TGCT cis rs6570726 0.791 rs7765675 chr6:145915077 A/C cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9653442 0.564 rs7590378 chr2:100789877 A/G cg22139774 chr2:100720529 AFF3 -0.35 -5.55 -0.45 1.63e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10089 1.000 rs7703634 chr5:127509223 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.4 0.55 1.83e-11 Ileal carcinoids; TGCT cis rs763121 0.853 rs2235230 chr22:39124467 A/G cg06022373 chr22:39101656 GTPBP1 -0.78 -6.86 -0.52 2.91e-10 Menopause (age at onset); TGCT cis rs270601 0.770 rs4361510 chr5:131599647 C/T cg24060327 chr5:131705240 SLC22A5 -0.66 -6.87 -0.53 2.75e-10 Acylcarnitine levels; TGCT cis rs36022378 0.504 rs4688688 chr3:50042690 C/G cg12257692 chr3:49977190 RBM6 -0.33 -5.32 -0.43 4.72e-7 Diastolic blood pressure; TGCT cis rs17253792 0.822 rs79747476 chr14:56160485 C/A cg01858014 chr14:56050164 KTN1 -0.35 -4.47 -0.37 1.73e-5 Putamen volume; TGCT cis rs6740322 0.748 rs6544634 chr2:43471528 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.2 -0.49 7.78e-9 Coronary artery disease; TGCT cis rs9300255 0.602 rs2695478 chr12:123689521 C/T cg00376283 chr12:123451042 ABCB9 0.72 4.99 0.41 2e-6 Neutrophil percentage of white cells; TGCT cis rs6835098 1.000 rs28477433 chr4:174085820 T/C cg08422745 chr4:174089978 GALNT7 -0.94 -11.2 -0.71 1.48e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs12477438 0.765 rs7340412 chr2:99661148 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT trans rs8076431 0.515 rs7213467 chr17:11254004 T/A cg16283179 chr19:3624140 C19orf29 -0.76 -7.33 -0.55 2.58e-11 IgG glycosylation; TGCT cis rs1005224 0.926 rs7143743 chr14:76127805 G/C cg04684003 chr14:76127793 TTLL5;C14orf1 -0.66 -6.06 -0.48 1.55e-8 Large artery stroke; TGCT cis rs10927875 0.632 rs10927863 chr1:16165247 C/A cg14742211 chr1:16348397 CLCNKA -0.19 -4.69 -0.39 7.1e-6 Dilated cardiomyopathy; TGCT cis rs13343954 0.778 rs10425324 chr19:33541302 C/T cg07624008 chr19:33672378 NA -0.28 -4.71 -0.39 6.43e-6 Colorectal cancer; TGCT cis rs2594989 0.887 rs2437684 chr3:11593261 C/T cg00170343 chr3:11313890 ATG7 -0.66 -5.0 -0.41 1.88e-6 Circulating chemerin levels; TGCT cis rs1525293 0.965 rs6963281 chr7:70490070 C/G cg21135135 chr7:70597687 WBSCR17 0.46 4.61 0.38 9.89e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs10927875 0.541 rs1763607 chr1:16337509 G/A cg21385522 chr1:16154831 NA 0.46 4.76 0.39 5.35e-6 Dilated cardiomyopathy; TGCT cis rs6088580 0.634 rs6059856 chr20:33057954 G/C cg06115741 chr20:33292138 TP53INP2 0.51 4.51 0.38 1.46e-5 Glomerular filtration rate (creatinine); TGCT cis rs11030122 0.547 rs4910865 chr11:3950546 T/C cg18678763 chr11:4115507 RRM1 -0.39 -4.76 -0.39 5.24e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs7267979 0.903 rs6132819 chr20:25218618 C/G cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs174449 0.603 rs174460 chr11:61657110 C/T cg19610905 chr11:61596333 FADS2 0.67 6.01 0.47 1.96e-8 Trans fatty acid levels; TGCT cis rs7089973 0.872 rs3180654 chr10:116615045 T/C cg03647239 chr10:116582469 FAM160B1 0.52 4.64 0.38 8.75e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7223966 1.000 rs752621 chr17:61901880 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs317689 0.718 rs315122 chr12:69771073 G/T cg11871910 chr12:69753446 YEATS4 0.54 4.6 0.38 1.02e-5 Response to diuretic therapy; TGCT cis rs12497850 0.829 rs8926 chr3:49052785 T/A cg18654377 chr3:49208889 KLHDC8B -0.41 -5.4 -0.44 3.33e-7 Parkinson's disease; TGCT cis rs950776 0.714 rs3743074 chr15:78909480 G/A cg06917634 chr15:78832804 PSMA4 -0.62 -4.95 -0.41 2.39e-6 Sudden cardiac arrest; TGCT trans rs4332037 0.664 rs73046334 chr7:1887037 T/C cg25206134 chr2:45395956 NA 0.93 7.88 0.58 1.43e-12 Bipolar disorder; TGCT cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg26119090 chr2:26468346 HADHA;HADHB -0.82 -5.77 -0.46 5.83e-8 Gut microbiome composition (summer); TGCT cis rs17221829 0.932 rs7924841 chr11:89460284 C/A cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.32e-6 Anxiety in major depressive disorder; TGCT cis rs765787 0.530 rs4544188 chr15:45535393 C/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT trans rs1005277 0.589 rs2749624 chr10:38529865 A/G cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs3806843 0.576 rs246036 chr5:140331886 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs644799 0.635 rs10831428 chr11:95508404 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.81 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2404602 0.735 rs2048856 chr15:76800083 C/T cg06069100 chr15:77574588 SGK269 0.27 4.74 0.39 5.68e-6 Blood metabolite levels; TGCT cis rs11030122 0.702 rs11030276 chr11:3946134 A/G cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs208515 0.525 rs10944869 chr6:66687576 G/T cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs497273 0.512 rs1177585 chr12:121325321 C/T cg02419362 chr12:121203948 SPPL3 -0.19 -4.51 -0.38 1.5e-5 Systemic lupus erythematosus; TGCT cis rs9393692 0.905 rs7761298 chr6:26278436 C/T cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9858542 0.953 rs35169793 chr3:49423274 A/G cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2463822 1.000 rs2513749 chr11:62105391 C/T cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2404602 0.692 rs35077207 chr15:76935306 A/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs8062405 1.000 rs7205323 chr16:28865892 C/T cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6964587 1.000 rs10234071 chr7:91645152 C/G cg22709100 chr7:91322751 NA -0.28 -4.6 -0.38 1.02e-5 Breast cancer; TGCT cis rs13108904 0.645 rs56115381 chr4:1324994 G/C cg13395646 chr4:1353034 KIAA1530 -0.54 -6.85 -0.52 3.1e-10 Obesity-related traits; TGCT trans rs208520 1.000 rs12193164 chr6:66978962 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs4783244 0.862 rs9939683 chr16:82653535 G/T cg09415485 chr16:82663111 CDH13 -0.24 -4.51 -0.38 1.47e-5 Adiponectin levels; TGCT cis rs7666738 0.830 rs1124253 chr4:98949682 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs769267 0.965 rs2315281 chr19:19480099 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.7 -5.93 -0.47 2.75e-8 Tonsillectomy; TGCT cis rs459571 0.916 rs467303 chr9:136904835 C/T cg13789015 chr9:136890014 NCRNA00094 0.41 7.58 0.56 7.09e-12 Platelet distribution width; TGCT trans rs1814175 0.904 rs1846289 chr11:49620253 G/A cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs2204008 0.546 rs11519978 chr12:37998170 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.22 0.42 7.4e-7 Bladder cancer; TGCT cis rs3796352 1.000 rs35576914 chr3:53092270 G/A cg07884673 chr3:53033167 SFMBT1 0.61 6.25 0.49 6e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg05738196 chr6:26577821 NA 0.88 11.96 0.73 2.18e-22 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.846 rs1660323 chr8:101278724 T/A cg06636551 chr8:101224915 SPAG1 -0.49 -6.83 -0.52 3.32e-10 Atrioventricular conduction; TGCT cis rs9581857 0.556 rs9581861 chr13:28039991 C/T cg22138327 chr13:27999177 GTF3A 0.73 5.63 0.45 1.13e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2980439 0.807 rs2980438 chr8:8094825 T/C cg15556689 chr8:8085844 FLJ10661 0.7 6.51 0.5 1.64e-9 Neuroticism; TGCT cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs1887596 0.629 rs1625599 chr13:27257688 C/T cg01312412 chr13:27282625 NA -0.31 -5.56 -0.45 1.56e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs4803468 0.967 rs4803461 chr19:41908871 G/A cg09537434 chr19:41945824 ATP5SL -0.93 -11.02 -0.7 4.1e-20 Height; TGCT cis rs10791323 0.569 rs1119851 chr11:133742842 T/C cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs4285028 0.747 rs1574133 chr3:121468794 G/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.96 -7.66 -0.57 4.71e-12 Multiple sclerosis; TGCT cis rs244731 0.959 rs3105419 chr5:176551396 G/C cg17509989 chr5:176798049 RGS14 0.58 6.71 0.52 6.17e-10 Urate levels in lean individuals; TGCT cis rs422249 0.512 rs174554 chr11:61579463 A/G cg01500311 chr11:61656094 FADS3 -0.3 -5.25 -0.43 6.42e-7 Trans fatty acid levels; TGCT cis rs10832169 0.967 rs10832171 chr11:14071734 A/G cg04547675 chr11:13986162 SPON1 0.53 4.73 0.39 6.04e-6 Blood protein levels; TGCT cis rs2721195 0.845 rs3757966 chr8:145744618 G/A cg11211951 chr8:145729740 GPT 0.27 6.59 0.51 1.1e-9 Age at first birth; TGCT cis rs10927875 0.662 rs698893 chr1:16302982 C/T cg21385522 chr1:16154831 NA 0.43 4.56 0.38 1.21e-5 Dilated cardiomyopathy; TGCT cis rs826838 0.967 rs1486345 chr12:39131677 G/A cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 6.33 0.49 4.08e-9 Alzheimer's disease; TGCT cis rs2535633 0.631 rs9823697 chr3:53002150 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.18 -0.42 8.63e-7 Body mass index; TGCT cis rs346785 0.666 rs9902690 chr17:74295140 A/G cg09812376 chr17:74270190 QRICH2 -0.35 -5.2 -0.42 8.14e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs10782582 0.593 rs11576534 chr1:76112751 C/T cg03433033 chr1:76189801 ACADM -0.61 -7.17 -0.54 5.91e-11 Daytime sleep phenotypes; TGCT cis rs6909430 0.539 rs34109912 chr6:98795355 C/T cg20000812 chr6:99276697 NA -0.52 -4.6 -0.38 1.03e-5 Quantitative traits; TGCT cis rs4494114 0.967 rs9439083 chr1:39344766 C/T cg25970120 chr1:39325951 RRAGC -0.6 -6.23 -0.49 6.58e-9 Blood protein levels; TGCT cis rs4664308 0.691 rs1877196 chr2:160915150 G/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.55 -0.51 1.36e-9 Idiopathic membranous nephropathy; TGCT cis rs11190604 0.767 rs11190533 chr10:102190792 T/C cg16005271 chr10:102321736 NA 0.45 4.7 0.39 6.81e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2224391 0.911 rs9504368 chr6:5261460 A/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -6.05 -0.48 1.61e-8 Height; TGCT cis rs10057188 1.000 rs10077632 chr5:77874940 C/T cg06873401 chr5:77792105 LHFPL2 -0.22 -4.49 -0.37 1.61e-5 Pulse pressure; TGCT cis rs12580194 0.593 rs7314118 chr12:55737403 A/C cg10672482 chr12:55725839 OR6C3 -0.53 -4.68 -0.39 7.28e-6 Cancer; TGCT cis rs10876993 0.890 rs7963927 chr12:58046272 T/G cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs4780355 0.918 rs1646019 chr16:11359680 C/T cg00044050 chr16:11439710 C16orf75 0.54 4.77 0.39 5.01e-6 Crohn's disease and psoriasis; TGCT cis rs694739 0.734 rs663743 chr11:64107735 G/A cg02228329 chr11:64053129 BAD;GPR137 0.7 6.55 0.51 1.36e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs3812831 0.669 rs7327370 chr13:114946858 A/G cg15513719 chr13:114904418 NA 0.37 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs6840360 0.593 rs6847844 chr4:152693246 C/T cg17479576 chr4:152424074 FAM160A1 -0.53 -5.26 -0.43 5.99e-7 Intelligence (multi-trait analysis); TGCT cis rs1800469 1.000 rs2241714 chr19:41869392 C/T cg09537434 chr19:41945824 ATP5SL 0.59 5.32 0.43 4.72e-7 Colorectal cancer; TGCT cis rs2677744 0.626 rs867468 chr15:91498127 G/A cg22570213 chr15:91497863 RCCD1 0.38 4.61 0.38 9.98e-6 Attention deficit hyperactivity disorder; TGCT cis rs933688 1.000 rs10073657 chr5:90689749 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 9.9 0.66 2.21e-17 Smoking behavior; TGCT cis rs7954584 0.545 rs12824593 chr12:122374108 G/A cg21016266 chr12:122356598 WDR66 0.53 6.62 0.51 9.84e-10 Mean corpuscular volume; TGCT cis rs2594989 0.943 rs2454508 chr3:11493232 T/C cg00170343 chr3:11313890 ATG7 0.69 5.1 0.42 1.26e-6 Circulating chemerin levels; TGCT cis rs8014204 0.743 rs35809608 chr14:75254762 A/G cg06637938 chr14:75390232 RPS6KL1 0.7 6.77 0.52 4.47e-10 Caffeine consumption; TGCT cis rs727505 0.789 rs66756015 chr7:124740641 C/A cg23710748 chr7:124431027 NA -0.26 -4.54 -0.38 1.33e-5 Lewy body disease; TGCT cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs7975161 0.515 rs7299866 chr12:104576197 C/T cg25273343 chr12:104657179 TXNRD1 -0.32 -6.03 -0.48 1.76e-8 Toenail selenium levels; TGCT cis rs4689388 0.890 rs4481292 chr4:6298375 C/T cg14416269 chr4:6271139 WFS1 0.4 5.32 0.43 4.78e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12220238 1.000 rs10824128 chr10:76007903 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.91 0.58 1.21e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9640161 0.750 rs3800780 chr7:150027284 C/A cg17279839 chr7:150038598 RARRES2 0.43 4.54 0.38 1.29e-5 Blood protein levels;Circulating chemerin levels; TGCT trans rs3780486 0.505 rs10117038 chr9:33122626 T/C cg20290983 chr6:43655470 MRPS18A 0.8 8.58 0.61 3.34e-14 IgG glycosylation; TGCT cis rs4478858 0.684 rs7549343 chr1:31752260 A/G cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs4665809 0.938 rs4665822 chr2:26312555 C/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs11190604 0.767 rs7916904 chr10:102186778 C/G cg16005271 chr10:102321736 NA 0.45 4.7 0.39 6.81e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs61931739 0.500 rs10772160 chr12:34456848 G/A cg06521331 chr12:34319734 NA -0.28 -4.52 -0.38 1.4e-5 Morning vs. evening chronotype; TGCT cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs950169 0.840 rs12905223 chr15:85114268 T/C cg17173187 chr15:85201210 NMB 0.47 4.93 0.4 2.62e-6 Schizophrenia; TGCT cis rs2075371 1.000 rs2544211 chr7:133973230 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.52 0.51 1.56e-9 Mean platelet volume; TGCT cis rs7666738 0.546 rs9993299 chr4:98815976 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.72 0.39 6.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs881375 0.678 rs3761846 chr9:123689597 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.3 0.43 5.07e-7 Rheumatoid arthritis; TGCT cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg16497277 chr3:49208875 KLHDC8B -0.58 -5.5 -0.44 2.08e-7 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9308731 0.505 rs10169613 chr2:111934977 C/T cg04202892 chr2:111875749 ACOXL 0.43 4.73 0.39 5.88e-6 Chronic lymphocytic leukemia; TGCT cis rs67311347 1.000 rs2276868 chr3:40498845 C/T cg17264618 chr3:40429014 ENTPD3 -0.35 -5.1 -0.42 1.21e-6 Renal cell carcinoma; TGCT trans rs1974653 0.672 rs9606235 chr22:20069172 A/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs9818758 0.607 rs11706189 chr3:49210833 C/A cg07636037 chr3:49044803 WDR6 -1.02 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs12682352 0.715 rs332039 chr8:8723651 C/G cg08975724 chr8:8085496 FLJ10661 0.54 5.05 0.41 1.53e-6 Neuroticism; TGCT cis rs259282 0.562 rs2021772 chr19:33107651 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.53 4.81 0.4 4.24e-6 Schizophrenia; TGCT cis rs7731657 0.537 rs4705995 chr5:130350688 G/A cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs1801251 1.000 rs7587309 chr2:233705702 G/T cg08000102 chr2:233561755 GIGYF2 -0.64 -6.48 -0.5 1.95e-9 Coronary artery disease; TGCT cis rs9354352 0.818 rs9453548 chr6:66691885 T/C cg07460842 chr6:66804631 NA -0.58 -5.84 -0.46 4.29e-8 Initial pursuit acceleration in psychotic disorders; TGCT cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs8062405 0.929 rs11864750 chr16:28875204 A/T cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs12681288 0.676 rs2701923 chr8:994605 A/G cg04851639 chr8:1020857 NA -0.31 -5.21 -0.42 7.57e-7 Schizophrenia; TGCT cis rs986417 0.748 rs9989223 chr14:60942525 C/A cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs28595532 0.920 rs115464801 chr4:119730673 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs6074578 0.679 rs1858594 chr20:138555 A/G cg16931068 chr20:139680 DEFB127 0.28 4.98 0.41 2.11e-6 Hirschsprung disease; TGCT cis rs394563 0.726 rs6906384 chr6:149664540 G/A cg16235748 chr6:149772707 ZC3H12D 0.5 5.95 0.47 2.55e-8 Dupuytren's disease; TGCT cis rs6430585 0.528 rs309113 chr2:136737460 C/A cg07169764 chr2:136633963 MCM6 1.18 11.33 0.71 7.22e-21 Corneal structure; TGCT cis rs9300255 0.602 rs1716172 chr12:123712712 G/T cg00376283 chr12:123451042 ABCB9 0.67 5.3 0.43 5.07e-7 Neutrophil percentage of white cells; TGCT cis rs1215050 0.791 rs503863 chr4:98707663 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10875746 0.669 rs61941003 chr12:48619625 G/A cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs9372498 0.536 rs724868 chr6:118795152 C/T cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.36e-7 Diastolic blood pressure; TGCT cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg02503808 chr4:7069936 GRPEL1 0.98 9.23 0.64 9.22e-16 Monocyte percentage of white cells; TGCT cis rs17030434 0.953 rs11099906 chr4:154691690 A/T cg14289246 chr4:154710475 SFRP2 -0.96 -7.72 -0.57 3.43e-12 Electrocardiographic conduction measures; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs734999 0.545 rs28568531 chr1:2555640 T/A cg18854424 chr1:2615690 NA 0.45 5.15 0.42 1e-6 Ulcerative colitis; TGCT cis rs7312933 0.618 rs6582394 chr12:42686189 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.58 5.42 0.44 3.03e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2982552 1.000 rs2982575 chr6:152069791 A/G cg22157087 chr6:152012887 ESR1 0.18 4.54 0.38 1.31e-5 Bone properties (heel); TGCT cis rs7267979 0.932 rs446649 chr20:25467359 A/G cg03522245 chr20:25566470 NINL 0.58 6.37 0.5 3.42e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7100689 0.646 rs1538819 chr10:82122523 A/G cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs240764 0.658 rs6925823 chr6:101179273 C/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg24675658 chr1:53192096 ZYG11B -0.7 -7.91 -0.58 1.22e-12 Monocyte count; TGCT cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg26119090 chr2:26468346 HADHA;HADHB 0.99 7.28 0.55 3.39e-11 Gut microbiome composition (summer); TGCT cis rs9814567 0.964 rs9847788 chr3:134186496 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.76 -0.66 4.96e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs11512640 0.826 rs11220091 chr11:125361138 C/T cg09813145 chr16:48012664 NA -0.57 -6.65 -0.51 8.31e-10 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs3008870 1.000 rs2815370 chr1:67503727 A/G cg03991309 chr1:68237761 GNG12 -0.27 -4.72 -0.39 6.32e-6 Lymphocyte percentage of white cells; TGCT cis rs11605924 1.000 rs1401419 chr11:45879739 T/C ch.11.939596F chr11:45881766 CRY2 -0.38 -4.67 -0.39 7.8e-6 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs9674544 0.757 rs9896443 chr17:47125982 A/G cg22947322 chr17:47091978 IGF2BP1 -0.25 -4.47 -0.37 1.75e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg21724239 chr8:58056113 NA 0.46 4.98 0.41 2.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs62103177 0.525 rs10438902 chr18:77745640 A/G cg07235805 chr18:78004237 PARD6G -0.46 -4.54 -0.38 1.32e-5 Opioid sensitivity; TGCT cis rs6693567 0.545 rs1260403 chr1:150303666 A/G cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs9400467 0.537 rs12214550 chr6:111505499 C/T cg15721981 chr6:111408429 SLC16A10 0.71 4.6 0.38 1.04e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs11105298 0.891 rs3741899 chr12:89933931 G/A cg00757033 chr12:89920650 WDR51B 0.29 4.6 0.38 1.01e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg07061783 chr6:25882402 NA -0.68 -6.83 -0.52 3.35e-10 Intelligence (multi-trait analysis); TGCT cis rs4268898 0.722 rs35520052 chr2:24415277 C/T cg02683114 chr2:24398427 C2orf84 0.19 4.7 0.39 6.78e-6 Asthma; TGCT cis rs9913156 0.841 rs56239958 chr17:4600280 G/C cg19197139 chr17:4613644 ARRB2 0.83 7.74 0.57 3.03e-12 Lymphocyte counts; TGCT cis rs9883204 1.000 rs56371916 chr3:123095543 T/C cg04890266 chr3:123102914 ADCY5 0.36 5.11 0.42 1.17e-6 Birth weight; TGCT cis rs9814567 0.752 rs4955544 chr3:134332776 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.45 -0.5 2.3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4455778 0.580 rs6951015 chr7:49115139 T/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs644799 0.930 rs3802764 chr11:95514599 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.53 0.61 4.41e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12753569 0.934 rs10430051 chr1:76491628 T/G cg01259156 chr1:75594592 LHX8 0.26 4.69 0.39 7.19e-6 Personality dimensions; TGCT cis rs6121246 0.567 rs7361893 chr20:30200751 C/T cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.39e-6 Mean corpuscular hemoglobin; TGCT cis rs270601 0.770 rs61352298 chr5:131600589 G/C cg12564285 chr5:131593104 PDLIM4 0.4 4.78 0.39 4.79e-6 Acylcarnitine levels; TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs79349575 0.715 rs999474 chr17:46987665 G/A cg26022315 chr17:47021804 SNF8 -0.54 -5.37 -0.43 3.73e-7 Type 2 diabetes; TGCT cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg27286337 chr10:134555280 INPP5A 0.4 4.91 0.4 2.76e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11696501 0.739 rs2235600 chr20:44238299 T/G cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs7226408 0.894 rs55797519 chr18:34386020 A/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.49e-10 Intelligence (multi-trait analysis); TGCT cis rs11690935 0.595 rs788166 chr2:172915489 G/C cg13550731 chr2:172543902 DYNC1I2 0.68 6.32 0.49 4.31e-9 Schizophrenia; TGCT cis rs17433780 0.964 rs12146148 chr1:89471892 C/T cg09516651 chr1:89888402 LOC400759 0.32 5.89 0.47 3.35e-8 Carotid intima media thickness; TGCT cis rs4851254 0.626 rs71413861 chr2:100673501 A/G cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg11375102 chr16:1583810 IFT140;TMEM204 -0.31 -5.51 -0.44 2e-7 Coronary artery disease; TGCT cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs2288884 1.000 rs2043298 chr19:52573067 A/C cg15405931 chr19:52693188 PPP2R1A 0.69 4.52 0.38 1.41e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg07061783 chr6:25882402 NA 0.58 5.59 0.45 1.39e-7 Intelligence (multi-trait analysis); TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg18110333 chr6:292329 DUSP22 -0.74 -7.88 -0.58 1.46e-12 Menopause (age at onset); TGCT cis rs17221829 0.590 rs10830300 chr11:89363066 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs3806843 0.548 rs246058 chr5:140325134 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs8016982 0.674 rs6574631 chr14:81675772 C/T cg01989461 chr14:81687754 GTF2A1 0.84 9.08 0.63 2.14e-15 Schizophrenia; TGCT cis rs4988958 0.527 rs11465641 chr2:103000868 T/G cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma (childhood onset); TGCT cis rs9818758 0.607 rs55873331 chr3:49597055 C/T cg08550065 chr3:50336684 HYAL3;NAT6 1.04 5.13 0.42 1.08e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7173743 0.525 rs7173955 chr15:79143857 A/G cg00540400 chr15:79124168 NA 0.18 4.52 0.38 1.4e-5 Coronary artery disease; TGCT cis rs2354432 0.556 rs2353975 chr1:146837703 C/A cg25205988 chr1:146714368 CHD1L 1.33 5.9 0.47 3.26e-8 Mitochondrial DNA levels; TGCT cis rs9814567 1.000 rs4334685 chr3:134304335 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs3784262 0.740 rs1441829 chr15:58289739 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.95 -0.47 2.58e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs3772130 0.962 rs9848027 chr3:121551227 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs4252435 0.522 rs10279865 chr7:142598708 C/T cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs9952991 0.941 rs888270 chr18:12774894 G/A cg09945482 chr18:12777974 NA -0.52 -4.73 -0.39 6.08e-6 Inflammatory skin disease; TGCT cis rs1997103 1.000 rs6945937 chr7:55407140 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7208859 0.623 rs73263788 chr17:29216490 T/C cg18442181 chr17:29233375 C17orf42 -0.76 -4.55 -0.38 1.27e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3749237 0.595 rs4855839 chr3:49507847 G/A cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs1218582 0.596 rs906595 chr1:154822907 C/T cg09359103 chr1:154839909 KCNN3 -0.52 -8.22 -0.59 2.36e-13 Prostate cancer; TGCT cis rs6752107 0.870 rs13003866 chr2:234143373 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.92 0.4 2.73e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2235642 0.750 rs1894649 chr16:1657284 C/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.29 -4.98 -0.41 2.06e-6 Coronary artery disease; TGCT cis rs11098499 0.954 rs1546505 chr4:120241224 A/G cg09307838 chr4:120376055 NA 0.65 6.01 0.48 1.9e-8 Corneal astigmatism; TGCT cis rs3771570 1.000 rs56052835 chr2:242243251 T/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs981844 0.826 rs1545604 chr4:154682733 C/T cg14289246 chr4:154710475 SFRP2 1.06 9.98 0.67 1.4e-17 Response to statins (LDL cholesterol change); TGCT cis rs644799 0.648 rs1255182 chr11:95472391 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.53 5.13 0.42 1.11e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4727027 1.000 rs4727027 chr7:148869277 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.59 0.38 1.07e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4455778 0.580 rs4285433 chr7:49114185 A/G cg26309511 chr7:48887640 NA 0.51 6.64 0.51 8.83e-10 Lung cancer in never smokers; TGCT cis rs7666738 0.830 rs7678250 chr4:98922109 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs478304 0.651 rs4930319 chr11:65555458 G/C cg10518572 chr11:65560635 OVOL1 -0.25 -4.76 -0.39 5.32e-6 Acne (severe); TGCT cis rs11098499 0.909 rs7681978 chr4:120383775 T/C cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs3784262 0.669 rs12905608 chr15:58314139 C/T cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.27 -0.49 5.58e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs751728 0.965 rs4713683 chr6:33757550 C/G cg13859433 chr6:33739653 LEMD2 -0.43 -7.94 -0.58 1.04e-12 Crohn's disease; TGCT cis rs79057730 0.639 rs6463933 chr7:793954 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.78 6.05 0.48 1.62e-8 Initial pursuit acceleration; TGCT cis rs6460942 0.908 rs7781919 chr7:12235351 T/C cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs9814567 1.000 rs6766818 chr3:134226159 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs644799 0.965 rs565771 chr11:95644179 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.84 10.28 0.68 2.67e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2594989 0.887 rs6442253 chr3:11474238 T/C cg00170343 chr3:11313890 ATG7 0.73 5.41 0.44 3.16e-7 Circulating chemerin levels; TGCT cis rs1541995 0.789 rs35974115 chr15:96231079 T/C cg00882281 chr15:96346592 NA 0.3 4.76 0.39 5.28e-6 Photic sneeze reflex; TGCT cis rs4925386 0.840 rs6143034 chr20:60920545 T/C cg06026331 chr20:60912101 LAMA5 0.36 5.99 0.47 2.09e-8 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs2224391 0.628 rs9405260 chr6:5249612 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.96 -5.44 -0.44 2.67e-7 Height; TGCT cis rs736408 0.716 rs2300149 chr3:52822921 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.55 -5.32 -0.43 4.68e-7 Bipolar disorder; TGCT cis rs2730260 0.537 rs73169233 chr7:158882201 C/T cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs6089829 0.962 rs6062777 chr20:61663748 G/A cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2046867 0.862 rs2322611 chr3:72830087 T/G cg25664220 chr3:72788482 NA -0.57 -7.07 -0.54 9.9e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs9859260 0.710 rs41298097 chr3:195779155 C/T cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg20007245 chr22:24372913 LOC391322 -0.74 -7.49 -0.56 1.11e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs916888 0.779 rs199528 chr17:44843136 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.6 -5.38 -0.43 3.65e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs709400 0.628 rs1951392 chr14:103853367 T/G cg26031613 chr14:104095156 KLC1 0.85 8.95 0.63 4.36e-15 Body mass index; TGCT cis rs61990749 0.686 rs11159288 chr14:78216972 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg23172400 chr8:95962367 TP53INP1 -0.38 -6.26 -0.49 5.71e-9 Type 2 diabetes; TGCT cis rs597539 0.652 rs501799 chr11:68631240 G/T cg06028808 chr11:68637592 NA 0.51 6.88 0.53 2.57e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs17221829 0.645 rs10830325 chr11:89389068 G/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs7394190 0.748 rs78790589 chr10:75539598 G/A cg07699608 chr10:75541558 CHCHD1 0.79 5.45 0.44 2.63e-7 Incident atrial fibrillation; TGCT cis rs2239547 0.657 rs12488303 chr3:52862003 G/A cg10802521 chr3:52805072 NEK4 -0.62 -5.85 -0.47 4.1e-8 Schizophrenia; TGCT cis rs1712790 0.613 rs2213072 chr11:114640554 G/C cg19978728 chr11:115335092 CADM1 0.3 4.76 0.39 5.23e-6 Urinary albumin excretion; TGCT cis rs295140 0.605 rs34693942 chr2:201184348 T/C cg23649088 chr2:200775458 C2orf69 -0.28 -4.52 -0.38 1.41e-5 QT interval; TGCT cis rs1555895 0.576 rs12413228 chr10:849230 G/T cg02193355 chr10:851439 NA 0.23 5.38 0.43 3.6e-7 Survival in rectal cancer; TGCT cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs2235642 0.653 rs7197288 chr16:1654753 C/A cg07639376 chr16:1584516 IFT140;TMEM204 -0.29 -4.97 -0.41 2.22e-6 Coronary artery disease; TGCT cis rs7264396 0.676 rs58372200 chr20:34555445 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs4971059 0.507 rs11264321 chr1:155085898 C/A cg23973274 chr1:155060172 NA -0.25 -4.51 -0.38 1.48e-5 Breast cancer; TGCT cis rs514406 0.505 rs269286 chr1:53169018 C/T cg08859206 chr1:53392774 SCP2 0.36 5.21 0.42 7.7e-7 Monocyte count; TGCT cis rs523522 0.673 rs643372 chr12:121022640 C/G cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs9788682 0.894 rs4461039 chr15:78817447 A/T cg06917634 chr15:78832804 PSMA4 0.69 5.09 0.42 1.29e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs354033 0.959 rs354041 chr7:149297035 A/C cg24335155 chr7:149193227 ZNF746 0.34 4.82 0.4 4.06e-6 Multiple sclerosis; TGCT cis rs2797780 0.964 rs75330988 chr6:37504507 C/T cg00985040 chr6:37553208 NA 0.25 4.8 0.4 4.48e-6 Systemic lupus erythematosus; TGCT cis rs4713118 0.868 rs742047 chr6:27739380 A/G cg20933634 chr6:27740509 NA 0.34 4.81 0.4 4.25e-6 Parkinson's disease; TGCT cis rs9640161 0.789 rs10952250 chr7:150025966 T/C cg10018233 chr7:150070692 REPIN1 0.32 4.66 0.39 8e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs2880765 0.566 rs55899824 chr15:86004091 C/T cg13263323 chr15:86062960 AKAP13 -0.2 -4.48 -0.37 1.68e-5 Coronary artery disease; TGCT cis rs910187 0.605 rs6124961 chr20:45804467 G/C cg27589058 chr20:45804311 EYA2 -0.38 -8.37 -0.6 1.02e-13 Migraine; TGCT cis rs11098499 0.754 rs7672778 chr4:120248585 A/G cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs644799 1.000 rs693364 chr11:95621926 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.84 9.44 0.65 2.8e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2439831 1.000 rs2256764 chr15:43735763 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.88 5.49 0.44 2.14e-7 Lung cancer in ever smokers; TGCT cis rs73110464 0.562 rs2363634 chr12:53354683 A/G cg25025879 chr12:53359317 NA -0.52 -5.56 -0.45 1.57e-7 Cancer (pleiotropy); TGCT cis rs79057730 0.684 rs6955004 chr7:790792 A/G cg11064039 chr7:766100 PRKAR1B;HEATR2 0.79 6.14 0.48 1.03e-8 Initial pursuit acceleration; TGCT cis rs7264396 0.790 rs6060539 chr20:34239382 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs9388451 0.869 rs7764016 chr6:126070789 T/G cg05901451 chr6:126070800 HEY2 -1.03 -15.09 -0.8 7.37e-30 Brugada syndrome; TGCT cis rs7937682 0.921 rs34584980 chr11:111441537 G/A cg09085632 chr11:111637200 PPP2R1B 0.84 6.68 0.51 7.09e-10 Primary sclerosing cholangitis; TGCT cis rs7210837 0.527 rs35353236 chr17:16788996 G/T cg00849854 chr17:17780937 TOM1L2 0.35 4.45 0.37 1.85e-5 Response to platinum-based chemotherapy (cisplatin); TGCT cis rs4285028 0.948 rs12493408 chr3:121692119 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.91 -9.53 -0.65 1.78e-16 Intelligence (multi-trait analysis); TGCT cis rs6752107 0.782 rs12692254 chr2:234161211 A/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.86 0.4 3.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6964587 1.000 rs12536529 chr7:91684086 C/T cg17063962 chr7:91808500 NA -0.86 -9.31 -0.64 6.01e-16 Breast cancer; TGCT cis rs7119 0.604 rs2271398 chr15:77907784 G/A cg27398640 chr15:77910606 LINGO1 0.32 6.88 0.53 2.63e-10 Type 2 diabetes; TGCT cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg02725872 chr8:58115012 NA -0.4 -4.83 -0.4 3.92e-6 Developmental language disorder (linguistic errors); TGCT cis rs6088590 1.000 rs6087625 chr20:33342477 A/G cg24642439 chr20:33292090 TP53INP2 -0.7 -6.26 -0.49 5.87e-9 Coronary artery disease; TGCT cis rs35146811 0.735 rs858512 chr7:99824453 A/G cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs231513 0.911 rs231521 chr17:41955158 A/G cg26893861 chr17:41843967 DUSP3 -0.76 -5.45 -0.44 2.62e-7 Cognitive function; TGCT cis rs6951245 0.554 rs35126802 chr7:1134842 C/T cg23708337 chr7:1209742 NA 0.44 4.87 0.4 3.27e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg16049864 chr8:95962084 TP53INP1 -0.6 -7.21 -0.54 4.92e-11 Type 2 diabetes; TGCT cis rs514406 0.607 rs6696940 chr1:53203427 C/T cg25767906 chr1:53392781 SCP2 0.46 5.1 0.42 1.24e-6 Monocyte count; TGCT cis rs4851266 1.000 rs11684761 chr2:100826871 C/A cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs7172809 0.599 rs11856084 chr15:77750410 T/G cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs7511006 1.000 rs17836662 chr22:50672154 A/G cg08875078 chr22:50639485 SELO -0.52 -4.93 -0.4 2.62e-6 Obesity-related traits; TGCT cis rs4321325 0.733 rs79995601 chr2:127947452 T/C cg09760422 chr2:128146352 NA 0.42 4.5 0.37 1.57e-5 Protein C levels; TGCT cis rs66573146 1.000 rs67067921 chr4:6984341 A/T cg01220768 chr4:7056774 TADA2B 0.39 4.91 0.4 2.77e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4478858 0.735 rs10914344 chr1:31769025 T/C cg00250761 chr1:31883323 NA -0.27 -4.96 -0.41 2.28e-6 Alcohol dependence; TGCT cis rs9921222 1.000 rs10794639 chr16:377367 A/G cg12437481 chr16:420112 MRPL28 -0.49 -5.21 -0.42 7.8e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs10464366 0.746 rs6945402 chr7:39145385 A/T cg18850127 chr7:39170497 POU6F2 0.3 6.61 0.51 1e-9 IgG glycosylation; TGCT cis rs11696845 0.776 rs6073538 chr20:43379264 A/C cg25301532 chr20:43378953 KCNK15 0.47 5.24 0.43 6.8e-7 Obesity-related traits; TGCT cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg11494091 chr17:61959527 GH2 0.42 7.39 0.55 1.86e-11 Height; TGCT cis rs6815814 0.731 rs66735315 chr4:38774180 G/T cg02016764 chr4:38805732 TLR1 -0.28 -4.79 -0.4 4.63e-6 Breast cancer; TGCT cis rs7267979 0.727 rs2474765 chr20:25245950 G/T cg14121845 chr20:25566513 NINL 0.45 4.8 0.4 4.44e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.57 5.14 0.42 1.03e-6 Height; TGCT cis rs11190604 1.000 rs2489051 chr10:102351785 C/T cg16342193 chr10:102329863 NA 0.39 5.41 0.44 3.13e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12643440 0.538 rs1357233 chr4:17143376 A/C cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs1218582 0.741 rs11264283 chr1:154869552 A/G cg03351412 chr1:154909251 PMVK 0.54 4.98 0.41 2.06e-6 Prostate cancer; TGCT cis rs34172651 0.517 rs200526 chr16:24760511 C/T cg06028605 chr16:24865363 SLC5A11 -0.42 -4.69 -0.39 7.14e-6 Intelligence (multi-trait analysis); TGCT cis rs9393692 0.905 rs9379843 chr6:26289435 A/G cg00631329 chr6:26305371 NA -0.45 -6.58 -0.51 1.16e-9 Educational attainment; TGCT cis rs2013441 1.000 rs17686839 chr17:20039171 A/G cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs1348850 0.914 rs6761593 chr2:178451600 A/G cg22681709 chr2:178499509 PDE11A 0.4 5.11 0.42 1.16e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs12497850 1.000 rs10865952 chr3:48744484 A/G cg07636037 chr3:49044803 WDR6 0.92 10.34 0.68 1.91e-18 Parkinson's disease; TGCT cis rs7666738 0.830 rs13144564 chr4:98939276 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs951366 1.000 rs951366 chr1:205685352 C/T cg07157834 chr1:205819609 PM20D1 0.32 4.53 0.38 1.37e-5 Menarche (age at onset); TGCT cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg18867708 chr6:26865862 GUSBL1 -0.38 -5.03 -0.41 1.65e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.888 rs13110683 chr4:98983368 G/C cg18180107 chr4:99064573 C4orf37 0.56 4.54 0.38 1.3e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs3784262 0.669 rs2414530 chr15:58356362 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9926296 0.632 rs7206546 chr16:89799079 C/T cg04287289 chr16:89883240 FANCA -0.64 -6.39 -0.5 3.08e-9 Vitiligo; TGCT cis rs11599315 0.507 rs12220554 chr10:1341852 C/T cg27336068 chr10:1336103 ADARB2 -0.34 -5.47 -0.44 2.41e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs2997447 0.846 rs2997445 chr1:26390154 C/T cg19633962 chr1:26362018 EXTL1 -0.68 -4.62 -0.38 9.47e-6 QRS complex (12-leadsum); TGCT cis rs1048238 0.506 rs7525608 chr1:16141901 A/G cg21385522 chr1:16154831 NA 0.58 6.38 0.5 3.21e-9 Systolic blood pressure; TGCT cis rs6500602 0.673 rs4786513 chr16:4576423 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.85 0.58 1.7e-12 Schizophrenia; TGCT cis rs79149102 0.579 rs76900720 chr15:75348895 A/T cg09165964 chr15:75287851 SCAMP5 -1.14 -6.16 -0.48 9.2e-9 Lung cancer; TGCT cis rs72945132 0.714 rs117232799 chr11:70157182 G/A cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs17376456 0.569 rs2924374 chr5:93151141 T/C cg21475434 chr5:93447410 FAM172A -0.63 -4.96 -0.41 2.23e-6 Diabetic retinopathy; TGCT cis rs1568889 1.000 rs12808162 chr11:28067027 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.87 0.62 6.72e-15 Bipolar disorder; TGCT cis rs5167 0.781 rs909134 chr19:45493061 T/C cg09555818 chr19:45449301 APOC2 0.24 5.11 0.42 1.2e-6 Blood protein levels; TGCT cis rs9807989 0.773 rs5010059 chr2:102968826 C/G cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs6426558 0.537 rs6682642 chr1:227244600 G/T cg10327440 chr1:227177885 CDC42BPA 0.57 7.03 0.53 1.22e-10 Neutrophil percentage of white cells; TGCT cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg13409248 chr3:40428643 ENTPD3 0.54 4.52 0.38 1.41e-5 Renal cell carcinoma; TGCT cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs13242816 1.000 rs73208106 chr7:116173263 G/A cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs2832191 0.791 rs2832197 chr21:30497790 T/C cg24692254 chr21:30365293 RNF160 -0.86 -9.11 -0.63 1.83e-15 Dental caries; TGCT cis rs7017914 0.935 rs6981435 chr8:71637148 T/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs10875746 0.951 rs61918826 chr12:48543978 T/C cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs17345786 0.906 rs11708616 chr3:101231731 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 8.92 0.63 5.18e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs73058052 0.597 rs16981329 chr19:50097932 G/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.59 0.45 1.4e-7 Fibrinogen levels; TGCT cis rs9486719 0.947 rs11755945 chr6:96908038 G/C cg06623918 chr6:96969491 KIAA0776 -0.98 -8.77 -0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs514406 0.763 rs7535088 chr1:53215042 A/G cg24675658 chr1:53192096 ZYG11B 0.71 7.96 0.58 9.48e-13 Monocyte count; TGCT cis rs11239930 0.538 rs4950359 chr1:146558743 C/A cg00044796 chr1:146552390 NA -0.35 -4.5 -0.37 1.54e-5 AIDS progression; TGCT cis rs7681440 0.904 rs7672979 chr4:90767873 A/G cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs1577917 1.000 rs1911553 chr6:86630892 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs11809207 0.951 rs111772533 chr1:26523404 C/G cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs2456568 0.802 rs11020585 chr11:93638493 A/C cg14065697 chr11:93583672 C11orf90 0.36 4.53 0.38 1.35e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9993613 0.875 rs7670141 chr4:73510707 G/A cg15102770 chr4:73434591 ADAMTS3 -0.52 -4.87 -0.4 3.28e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs11731606 0.508 rs12108275 chr4:95298847 T/G cg00507259 chr4:95128692 SMARCAD1 0.63 4.72 0.39 6.14e-6 Mean platelet volume; TGCT cis rs4642101 0.793 rs6763619 chr3:12822147 T/G cg05775895 chr3:12838266 CAND2 0.79 8.91 0.62 5.38e-15 QRS complex (12-leadsum); TGCT trans rs561341 1.000 rs501312 chr17:30329066 A/G cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs4253772 0.744 rs4253760 chr22:46622384 T/G cg09491104 chr22:46646882 C22orf40 -0.47 -4.62 -0.38 9.58e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs13191362 1.000 rs34228197 chr6:163008232 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9611519 0.542 rs8139770 chr22:41416181 C/T cg03806693 chr22:41940476 POLR3H -0.64 -6.08 -0.48 1.38e-8 Neuroticism; TGCT cis rs3008870 1.000 rs2755256 chr1:67471692 A/T cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs478304 0.934 rs498354 chr11:65528213 A/G cg27068330 chr11:65405492 SIPA1 0.75 7.57 0.56 7.2e-12 Acne (severe); TGCT cis rs9916302 0.800 rs11869259 chr17:37518141 C/A cg15445000 chr17:37608096 MED1 -0.33 -4.74 -0.39 5.87e-6 Glomerular filtration rate (creatinine); TGCT cis rs4654899 0.785 rs10916911 chr1:21290061 C/T cg01072550 chr1:21505969 NA -0.54 -8.87 -0.62 6.79e-15 Superior frontal gyrus grey matter volume; TGCT cis rs1635 0.655 rs73742535 chr6:28302925 G/A cg15743358 chr6:28303923 ZNF323 -1.28 -6.27 -0.49 5.57e-9 Schizophrenia; TGCT cis rs12893668 0.703 rs7148456 chr14:104028270 C/T cg26031613 chr14:104095156 KLC1 0.54 4.55 0.38 1.28e-5 Reticulocyte count; TGCT cis rs7726839 0.507 rs56282020 chr5:596701 T/C cg09021430 chr5:549028 NA -0.43 -5.74 -0.46 6.95e-8 Obesity-related traits; TGCT cis rs7917772 0.503 rs7893155 chr10:104294228 C/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10984561 0.786 rs77747958 chr9:122196767 T/A cg14242995 chr9:122249943 NA 0.62 5.19 0.42 8.25e-7 Pulmonary function decline; TGCT cis rs9467711 0.659 rs36014129 chr6:25884519 G/A cg16898833 chr6:26189333 HIST1H4D 1.32 5.63 0.45 1.16e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12765878 0.580 rs11191839 chr10:105634895 G/A cg11005552 chr10:105648138 OBFC1 -0.4 -6.28 -0.49 5.19e-9 Coronary artery disease; TGCT cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg17554472 chr22:41940697 POLR3H -0.5 -5.14 -0.42 1.04e-6 Vitiligo; TGCT cis rs8014204 0.762 rs12891131 chr14:75240090 A/G cg06637938 chr14:75390232 RPS6KL1 0.58 5.13 0.42 1.11e-6 Caffeine consumption; TGCT cis rs9330316 0.632 rs7596172 chr2:110339623 G/A cg25199208 chr2:109402912 CCDC138 -0.41 -4.44 -0.37 1.99e-5 Schizophrenia; TGCT cis rs76935404 0.811 rs28417358 chr19:41428105 G/A cg19493303 chr19:41414353 NA 0.41 5.07 0.41 1.43e-6 nicotine metabolite ratio in current smokers; TGCT cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg15659132 chr6:26577336 NA 0.87 11.0 0.7 4.77e-20 Intelligence (multi-trait analysis); TGCT cis rs7681440 0.904 rs2870029 chr4:90772057 G/T cg20003494 chr4:90757398 SNCA -0.59 -5.52 -0.44 1.9e-7 Dementia with Lewy bodies; TGCT cis rs7100689 0.524 rs7902460 chr10:82199263 T/A cg00277334 chr10:82204260 NA -0.4 -5.0 -0.41 1.94e-6 Post bronchodilator FEV1; TGCT cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg08219700 chr8:58056026 NA 0.38 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs78456975 0.527 rs7590743 chr2:1575048 A/G cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9926296 0.607 rs2079672 chr16:89884917 A/G cg04287289 chr16:89883240 FANCA -0.69 -7.08 -0.54 9.59e-11 Vitiligo; TGCT cis rs2880765 0.835 rs2170736 chr15:86043398 A/G cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs597539 0.652 rs686877 chr11:68637169 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg24846343 chr22:24311635 DDTL 0.22 5.65 0.45 1.05e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7236492 0.748 rs8092987 chr18:77208141 C/T cg15644404 chr18:77186268 NFATC1 -0.35 -4.57 -0.38 1.15e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs6840360 1.000 rs3749563 chr4:152596508 T/C cg17479576 chr4:152424074 FAM160A1 -0.5 -5.26 -0.43 6.16e-7 Intelligence (multi-trait analysis); TGCT cis rs4689388 0.890 rs4689398 chr4:6302199 C/T cg00701064 chr4:6280414 WFS1 0.44 5.85 0.47 4.08e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7786808 0.649 rs1377374 chr7:158215647 G/T cg01191920 chr7:158217561 PTPRN2 0.38 5.74 0.46 6.98e-8 Obesity-related traits; TGCT cis rs6964587 0.773 rs12536421 chr7:92008220 A/G cg17063962 chr7:91808500 NA 0.83 8.04 0.59 6.09e-13 Breast cancer; TGCT cis rs7095607 0.630 rs7069569 chr10:69955140 T/A cg18986048 chr10:69913749 MYPN 0.56 6.0 0.47 2e-8 Lung function (FVC); TGCT cis rs12681287 0.547 rs6998303 chr8:87510185 T/C cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs6977660 0.714 rs10486365 chr7:19801364 A/G cg07541023 chr7:19748670 TWISTNB 0.77 4.58 0.38 1.12e-5 Thyroid stimulating hormone; TGCT cis rs155076 1.000 rs261431 chr13:21865738 A/G cg11317459 chr13:21872234 NA 1.42 12.92 0.76 1.05e-24 White matter hyperintensity burden; TGCT cis rs12421382 0.507 rs2186673 chr11:109285519 G/A cg27471124 chr11:109292789 C11orf87 0.54 6.3 0.49 4.62e-9 Schizophrenia; TGCT cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs12701220 0.894 rs10263252 chr7:1049949 G/A cg27454412 chr7:1067447 C7orf50 -0.5 -4.75 -0.39 5.51e-6 Bronchopulmonary dysplasia; TGCT cis rs61935443 0.720 rs10859785 chr12:95295081 A/T cg21533806 chr12:95267307 NA 0.54 4.67 0.39 7.66e-6 Schizophrenia; TGCT cis rs6815814 0.950 rs11725779 chr4:38811668 G/A cg02016764 chr4:38805732 TLR1 -0.36 -5.71 -0.46 7.91e-8 Breast cancer; TGCT cis rs1218582 0.741 rs7544528 chr1:154844585 C/T cg06221963 chr1:154839813 KCNN3 -0.82 -15.79 -0.82 1.86e-31 Prostate cancer; TGCT cis rs2228479 1.000 rs62052186 chr16:89969567 A/T cg06558623 chr16:89946397 TCF25 0.57 6.58 0.51 1.18e-9 Skin colour saturation; TGCT cis rs7635838 0.750 rs7625680 chr3:11378069 G/A cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs875971 0.862 rs6460290 chr7:65809106 G/A cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.43e-7 Aortic root size; TGCT trans rs288326 0.704 rs2118588 chr2:183704681 C/G cg06580014 chr4:25931115 C4orf52 0.68 6.8 0.52 3.96e-10 Blood protein levels; TGCT cis rs250677 0.687 rs185155 chr5:148455893 T/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs380904 0.963 rs410836 chr8:144576849 A/G cg12686110 chr8:144635478 GSDMD 0.56 4.56 0.38 1.21e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs7772486 0.686 rs7744014 chr6:146123818 G/A cg05347473 chr6:146136440 FBXO30 0.47 4.48 0.37 1.7e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.861 rs9903363 chr17:37499604 C/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs1862618 0.525 rs2662019 chr5:56263104 A/G cg24549020 chr5:56110836 MAP3K1 -0.63 -4.81 -0.4 4.37e-6 Initial pursuit acceleration; TGCT cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg13699009 chr12:122356056 WDR66 0.26 5.4 0.44 3.31e-7 Mean corpuscular volume; TGCT cis rs11627546 0.615 rs61980576 chr14:70364769 G/A cg10496350 chr14:71275911 MAP3K9 -0.91 -4.53 -0.38 1.38e-5 Red blood cell traits; TGCT cis rs9807989 0.507 rs6749014 chr2:103006448 C/T cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs2456568 0.803 rs10765642 chr11:93640355 C/T cg14065697 chr11:93583672 C11orf90 0.36 4.55 0.38 1.25e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2404602 0.692 rs34181263 chr15:77065388 C/T cg22467129 chr15:76604101 ETFA -0.44 -4.96 -0.41 2.27e-6 Blood metabolite levels; TGCT cis rs7781977 0.782 rs1993444 chr7:50338499 G/A cg01139861 chr7:50343298 IKZF1 0.49 5.15 0.42 9.88e-7 IgG glycosylation; TGCT cis rs589249 1.000 rs589249 chr1:37162352 A/G cg04012535 chr1:37176647 NA -0.33 -5.21 -0.42 7.59e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs4319547 1.000 rs6489071 chr12:123025576 C/G cg23029597 chr12:123009494 RSRC2 -0.3 -4.96 -0.41 2.26e-6 Body mass index; TGCT cis rs610932 0.517 rs604085 chr11:59977401 G/A cg18570331 chr11:60101691 MS4A6E 0.52 4.75 0.39 5.44e-6 Alzheimer's disease; TGCT cis rs7119038 0.774 rs11217020 chr11:118639353 G/A cg19308663 chr11:118741387 NA 0.3 5.59 0.45 1.37e-7 Sjögren's syndrome; TGCT cis rs739496 0.579 rs10849985 chr12:112347754 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7208859 0.623 rs6505207 chr17:29076571 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9534288 0.797 rs2404727 chr13:46581697 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT trans rs459571 0.920 rs2520094 chr9:136919985 A/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.74 -7.83 -0.58 1.87e-12 Platelet distribution width; TGCT cis rs4443100 0.535 rs13055979 chr22:23474085 C/T cg14186256 chr22:23484241 RTDR1 0.62 5.29 0.43 5.32e-7 Serum parathyroid hormone levels; TGCT cis rs910316 0.763 rs13712 chr14:75483812 T/C cg11812906 chr14:75593930 NEK9 0.58 5.55 0.45 1.68e-7 Height; TGCT trans rs1075232 0.677 rs72714666 chr15:31492226 T/C cg05369791 chr7:130131146 MESTIT1;MEST 0.91 6.71 0.52 6.19e-10 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs1475911 0.708 rs56109792 chr21:43520060 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 0.64 9.39 0.64 3.87e-16 IgG glycosylation; TGCT cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs10744422 1.000 rs7139055 chr12:123364198 A/G cg25930673 chr12:123319894 HIP1R 0.86 5.02 0.41 1.73e-6 Schizophrenia; TGCT cis rs11190604 1.000 rs10883507 chr10:102291275 C/T cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg18765753 chr7:1198926 ZFAND2A -0.52 -6.03 -0.48 1.75e-8 Longevity;Endometriosis; TGCT cis rs6545883 0.894 rs12622458 chr2:61523554 A/C cg15711740 chr2:61764176 XPO1 0.56 4.81 0.4 4.21e-6 Tuberculosis; TGCT cis rs9653442 0.527 rs11123812 chr2:100761548 T/C cg07810366 chr2:100720526 AFF3 -0.36 -5.31 -0.43 4.89e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs1949733 0.636 rs16842498 chr4:8539529 C/T cg13073564 chr4:8508604 NA 0.49 4.8 0.4 4.48e-6 Response to antineoplastic agents; TGCT cis rs8026198 0.929 rs12441642 chr15:42515276 C/G cg13682096 chr15:43513306 EPB42 0.3 4.49 0.37 1.59e-5 Fibrinogen levels; TGCT cis rs11650494 0.908 rs9891264 chr17:47407342 T/A cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs12682352 0.579 rs7006589 chr8:8668486 A/G cg15556689 chr8:8085844 FLJ10661 0.57 5.0 0.41 1.95e-6 Neuroticism; TGCT cis rs6598955 0.671 rs11247896 chr1:26600483 A/G cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg13665807 chr20:60559372 TAF4 -0.42 -4.5 -0.37 1.52e-5 Body mass index; TGCT cis rs877426 0.591 rs56188498 chr13:114827804 A/G cg16820615 chr13:114884918 RASA3 0.33 5.35 0.43 4.05e-7 Facial morphology (factor 14, intercanthal width); TGCT cis rs13326165 0.760 rs2016575 chr3:52477080 T/C cg27565382 chr3:53032988 SFMBT1 -0.37 -4.9 -0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs35146811 0.735 rs2528900 chr7:99805319 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs12541335 0.615 rs4872464 chr8:22153381 G/A cg02788857 chr8:22132959 PIWIL2 0.26 4.57 0.38 1.15e-5 Hypertriglyceridemia; TGCT cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg06108461 chr20:60628389 TAF4 -0.6 -8.6 -0.61 2.88e-14 Body mass index; TGCT cis rs10791323 0.660 rs10791332 chr11:133732150 A/G cg03690763 chr11:133734501 NA -0.28 -4.48 -0.37 1.66e-5 Childhood ear infection; TGCT cis rs59197085 0.515 rs17165191 chr7:128451004 T/C cg00260937 chr7:128520193 KCP 0.46 5.06 0.41 1.49e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs6121246 0.909 rs6060793 chr20:30288830 T/G cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs17473412 0.609 rs7705070 chr5:122862876 C/T cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs68170813 0.641 rs79328953 chr7:106901557 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.26e-7 Coronary artery disease; TGCT cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg17345569 chr6:42928274 GNMT -0.48 -5.01 -0.41 1.81e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.01 0.48 1.87e-8 Cognitive function; TGCT cis rs3125734 0.653 rs1007976 chr10:63970144 C/T cg09941381 chr10:64027924 RTKN2 0.36 5.42 0.44 3.04e-7 Rheumatoid arthritis; TGCT cis rs988712 0.705 rs4244531 chr11:27657250 A/G cg10635145 chr11:27742435 BDNF -0.38 -5.23 -0.43 7e-7 Obesity; TGCT cis rs1538970 0.816 rs34673142 chr1:45985561 G/A cg05343316 chr1:45956843 TESK2 0.78 6.07 0.48 1.47e-8 Platelet count; TGCT cis rs7246657 0.882 rs6508719 chr19:37877419 A/G cg03233940 chr19:37894644 NA -0.35 -4.54 -0.38 1.3e-5 Coronary artery calcification; TGCT cis rs17030434 0.784 rs6835640 chr4:154650494 C/T cg14289246 chr4:154710475 SFRP2 -0.87 -7.36 -0.55 2.23e-11 Electrocardiographic conduction measures; TGCT cis rs1205863 0.607 rs864244 chr6:11929602 C/A cg07106625 chr6:11870215 NA 0.47 4.73 0.39 6.09e-6 Disc degeneration (lumbar); TGCT cis rs2980439 0.557 rs2921056 chr8:8319182 T/C cg06636001 chr8:8085503 FLJ10661 0.79 7.34 0.55 2.4e-11 Neuroticism; TGCT cis rs617219 0.726 rs1962002 chr5:78430689 T/C cg05890484 chr5:78407552 BHMT 0.39 5.34 0.43 4.35e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9811920 0.609 rs793447 chr3:99598278 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.58 -6.55 -0.51 1.35e-9 Axial length; TGCT cis rs1008375 1.000 rs7671752 chr4:17661398 C/T cg10189774 chr4:17578691 LAP3 0.56 5.04 0.41 1.57e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2075371 1.000 rs2075371 chr7:133984127 A/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs7572733 0.555 rs13395030 chr2:198750806 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg00786635 chr1:25594202 NA -0.53 -5.58 -0.45 1.41e-7 Erythrocyte sedimentation rate; TGCT cis rs11864453 0.647 rs10492813 chr16:72122463 A/G cg14768367 chr16:72042858 DHODH -0.51 -5.05 -0.41 1.56e-6 Fibrinogen levels; TGCT cis rs9357506 1.000 rs6934171 chr6:46316742 G/C cg21115430 chr6:46460003 NA -0.26 -5.05 -0.41 1.53e-6 Body mass index; TGCT cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg04025307 chr7:1156635 C7orf50 0.24 5.76 0.46 6.22e-8 Longevity;Endometriosis; TGCT cis rs6815814 0.851 rs11736207 chr4:38766285 G/A cg02016764 chr4:38805732 TLR1 -0.33 -5.13 -0.42 1.08e-6 Breast cancer; TGCT cis rs7584330 0.868 rs58057291 chr2:238395479 T/A cg14458575 chr2:238380390 NA 0.57 8.58 0.61 3.25e-14 Prostate cancer; TGCT cis rs8051431 0.840 rs6499556 chr16:72017298 A/G cg06353428 chr16:71660113 MARVELD3 0.58 4.62 0.38 9.32e-6 LDL cholesterol levels; TGCT cis rs40363 0.645 rs250633 chr16:3523002 C/T cg22508957 chr16:3507546 NAT15 0.49 5.58 0.45 1.41e-7 Tuberculosis; TGCT cis rs8033133 0.647 rs1124767 chr15:25326173 T/C cg14481604 chr15:25334117 SNORD116-22 -0.24 -5.32 -0.43 4.77e-7 Blood osmolality (transformed sodium); TGCT cis rs1992660 0.528 rs6883302 chr5:40411414 C/T cg01087697 chr5:40835557 RPL37 0.55 4.96 0.41 2.22e-6 Crohn's disease; TGCT cis rs2180341 0.920 rs1073931 chr6:127681762 A/T cg24812749 chr6:127587940 RNF146 0.93 7.4 0.55 1.83e-11 Breast cancer; TGCT cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg04944784 chr2:26401820 FAM59B -0.75 -6.36 -0.5 3.5e-9 Gut microbiome composition (summer); TGCT cis rs910187 0.597 rs2073172 chr20:45809176 A/G cg27589058 chr20:45804311 EYA2 -0.37 -8.26 -0.6 1.9e-13 Migraine; TGCT cis rs7095607 0.742 rs10997965 chr10:69923835 A/G cg18986048 chr10:69913749 MYPN 0.49 5.79 0.46 5.36e-8 Lung function (FVC); TGCT cis rs2013441 1.000 rs2703799 chr17:20085768 G/T cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs17030434 0.834 rs6843172 chr4:154760600 T/C cg14289246 chr4:154710475 SFRP2 -0.91 -7.82 -0.57 1.98e-12 Electrocardiographic conduction measures; TGCT cis rs7647973 0.626 rs2131108 chr3:49665390 C/T cg03060546 chr3:49711283 APEH 0.62 5.43 0.44 2.86e-7 Menarche (age at onset); TGCT cis rs3617 0.625 rs6445541 chr3:52880128 G/T cg11645453 chr3:52864694 ITIH4 0.27 5.11 0.42 1.21e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2013441 1.000 rs2107566 chr17:20103252 C/T cg18979559 chr17:20280153 CCDC144C -0.46 -4.84 -0.4 3.81e-6 Obesity-related traits; TGCT cis rs35306767 0.668 rs35657988 chr10:1103590 A/G cg20503657 chr10:835505 NA 0.44 4.83 0.4 3.9e-6 Eosinophil percentage of granulocytes; TGCT cis rs6912958 0.781 rs2207146 chr6:88180641 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs8017423 0.967 rs7142513 chr14:90705182 T/C cg04374321 chr14:90722782 PSMC1 0.78 7.88 0.58 1.45e-12 Mortality in heart failure; TGCT cis rs2439831 0.681 rs28594657 chr15:43588888 C/A cg02155558 chr15:43621948 ADAL;LCMT2 1.12 7.16 0.54 6.1e-11 Lung cancer in ever smokers; TGCT cis rs6570726 0.791 rs11155432 chr6:145898761 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.51 5.4 0.44 3.28e-7 Lymphocyte counts; TGCT cis rs9467773 1.000 rs6940053 chr6:26562122 C/T cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs6504663 0.586 rs60117965 chr17:48569755 G/A cg03168497 chr17:48586147 MYCBPAP 0.56 5.88 0.47 3.5e-8 Visceral fat; TGCT cis rs7552404 0.727 rs61770533 chr1:76306490 C/G cg10523679 chr1:76189770 ACADM 0.74 7.08 0.54 9.41e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2688608 0.620 rs11000767 chr10:75516626 G/T cg15838173 chr10:75533400 FUT11 -0.3 -5.02 -0.41 1.76e-6 Inflammatory bowel disease; TGCT cis rs2439831 0.681 rs2278858 chr15:43632755 G/T cg02155558 chr15:43621948 ADAL;LCMT2 1.06 7.72 0.57 3.41e-12 Lung cancer in ever smokers; TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs9443189 0.570 rs276684 chr6:76427065 A/G cg01950844 chr6:76311363 SENP6 -0.99 -6.07 -0.48 1.47e-8 Prostate cancer; TGCT cis rs595982 0.527 rs55670257 chr19:49382654 G/A cg17863274 chr19:49399704 TULP2 -0.53 -7.73 -0.57 3.1e-12 Red cell distribution width; TGCT cis rs10504229 0.593 rs16921626 chr8:58040359 C/T cg20607798 chr8:58055168 NA 0.45 4.68 0.39 7.52e-6 Developmental language disorder (linguistic errors); TGCT cis rs9911578 0.967 rs6416932 chr17:57148991 G/A cg12560992 chr17:57184187 TRIM37 0.79 9.71 0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.626 rs4855833 chr3:49657441 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs4803468 0.967 rs4605279 chr19:41888131 C/G cg09537434 chr19:41945824 ATP5SL -0.88 -9.94 -0.67 1.73e-17 Height; TGCT cis rs2013441 1.000 rs9905493 chr17:20188581 C/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs7599312 0.534 rs7355673 chr2:213404389 T/C cg20637307 chr2:213403960 ERBB4 0.91 11.8 0.73 5.21e-22 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs13326165 0.715 rs11716017 chr3:52380991 C/T cg27565382 chr3:53032988 SFMBT1 0.36 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7666738 0.791 rs10856934 chr4:99010844 A/G cg17366294 chr4:99064904 C4orf37 -0.61 -5.59 -0.45 1.4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1903068 0.853 rs9997685 chr4:56022903 A/T cg01777861 chr4:56023843 NA 0.54 5.95 0.47 2.57e-8 Endometriosis; TGCT cis rs1372520 0.684 rs356188 chr4:90691537 T/C cg15133208 chr4:90757351 SNCA 0.47 5.58 0.45 1.43e-7 Neuroticism; TGCT cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg03060546 chr3:49711283 APEH 0.53 5.14 0.42 1.05e-6 Menarche (age at onset); TGCT trans rs7698623 0.850 rs1477604 chr4:88771060 C/T cg12051260 chr11:78380599 ODZ4 -0.63 -6.62 -0.51 9.95e-10 Cardiovascular disease risk factors; TGCT trans rs1814175 0.754 rs10219245 chr11:49645052 C/T cg03929089 chr4:120376271 NA -0.74 -8.94 -0.63 4.49e-15 Height; TGCT cis rs57221529 0.664 rs72704802 chr5:554211 C/T cg09021430 chr5:549028 NA -0.4 -5.34 -0.43 4.25e-7 Lung disease severity in cystic fibrosis; TGCT cis rs17376456 0.569 rs11948511 chr5:93286601 A/C cg21475434 chr5:93447410 FAM172A -0.64 -6.0 -0.47 1.99e-8 Diabetic retinopathy; TGCT cis rs9916302 0.851 rs9909064 chr17:37500434 G/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT trans rs1005277 0.579 rs2505194 chr10:38393881 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.65 0.61 2.22e-14 Extrinsic epigenetic age acceleration; TGCT cis rs9985766 1.000 rs28413051 chr4:151001278 G/A cg05926478 chr4:151174724 DCLK2 -0.31 -5.79 -0.46 5.39e-8 Coronary artery disease;Myocardial infarction; TGCT cis rs9914988 0.725 rs66531973 chr17:27125993 G/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9291683 0.588 rs12507330 chr4:10002195 G/A cg00071950 chr4:10020882 SLC2A9 0.73 9.56 0.65 1.46e-16 Bone mineral density; TGCT cis rs8177179 0.565 rs4355280 chr3:133468425 A/G cg08048268 chr3:133502702 NA -0.38 -4.61 -0.38 9.86e-6 Iron status biomarkers (transferrin levels); TGCT cis rs10791323 0.604 rs2853115 chr11:133707908 C/T cg03690763 chr11:133734501 NA 0.3 4.71 0.39 6.48e-6 Childhood ear infection; TGCT cis rs62380364 0.565 rs40504 chr5:88011139 G/C cg22951263 chr5:87985283 NA -0.58 -6.19 -0.49 7.88e-9 Intelligence (multi-trait analysis); TGCT cis rs4746818 1.000 rs10823313 chr10:70952115 G/A cg04149295 chr10:70884716 VPS26A 0.78 5.32 0.43 4.7e-7 Left atrial antero-posterior diameter; TGCT cis rs1990950 0.692 rs4704862 chr5:156857630 T/C cg25387487 chr5:157003181 ADAM19 0.31 4.65 0.39 8.2e-6 Lung function (FEV1/FVC); TGCT cis rs7590720 1.000 rs4674058 chr2:216909368 A/G cg12620499 chr2:216877984 MREG 0.87 8.73 0.62 1.48e-14 Alcohol dependence; TGCT cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs2299587 0.527 rs10112643 chr8:17726019 A/G cg01800426 chr8:17659068 MTUS1 -0.55 -4.96 -0.41 2.25e-6 Economic and political preferences; TGCT cis rs9650657 0.515 rs6601560 chr8:10950866 T/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.51 -0.38 1.47e-5 Neuroticism; TGCT cis rs875971 0.660 rs801192 chr7:66031952 C/G cg18876405 chr7:65276391 NA -0.37 -5.58 -0.45 1.47e-7 Aortic root size; TGCT cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs711245 0.637 rs6729495 chr2:36834192 T/A cg09467607 chr2:36825704 FEZ2 0.38 5.79 0.46 5.38e-8 Height; TGCT cis rs2120019 1.000 rs2415253 chr15:75375699 A/G cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT cis rs155076 1.000 rs9509638 chr13:21860193 G/A cg11317459 chr13:21872234 NA -1.32 -10.89 -0.7 8.4e-20 White matter hyperintensity burden; TGCT cis rs765787 0.530 rs11070445 chr15:45513163 T/A cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg23205692 chr1:25664452 TMEM50A 0.48 5.0 0.41 1.92e-6 Plateletcrit;Mean corpuscular volume; TGCT cis rs9650657 0.645 rs4841409 chr8:10516374 C/T cg27411982 chr8:10470053 RP1L1 0.22 4.97 0.41 2.15e-6 Neuroticism; TGCT cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg16497277 chr3:49208875 KLHDC8B -0.54 -5.17 -0.42 9.07e-7 Menarche (age at onset); TGCT trans rs3780486 0.718 rs3818593 chr9:33120706 A/G cg20290983 chr6:43655470 MRPS18A 0.98 7.4 0.55 1.85e-11 IgG glycosylation; TGCT cis rs7659604 0.702 rs58649165 chr4:122693752 C/A cg19748678 chr4:122722346 EXOSC9 0.84 9.03 0.63 2.75e-15 Type 2 diabetes; TGCT cis rs12210905 1.000 rs72843641 chr6:27203335 C/G cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT cis rs2730245 0.528 rs1188954 chr7:158691417 G/A cg11984989 chr7:158649758 WDR60 1.09 10.52 0.69 6.69e-19 Height; TGCT cis rs17001868 0.527 rs11913132 chr22:40778778 A/G cg07138101 chr22:40742427 ADSL 0.74 5.68 0.45 9.15e-8 Mammographic density (dense area); TGCT cis rs9905704 0.647 rs11650809 chr17:56972741 A/G cg12560992 chr17:57184187 TRIM37 0.58 4.93 0.4 2.57e-6 Testicular germ cell tumor; TGCT cis rs7412746 0.611 rs10888394 chr1:150749913 C/T cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs10510102 0.872 rs12246693 chr10:123716888 T/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs1153858 1.000 rs10519022 chr15:45663684 C/T cg26924012 chr15:45694286 SPATA5L1 -1.13 -13.32 -0.77 1.12e-25 Homoarginine levels; TGCT cis rs72781680 1.000 rs72788280 chr2:24095907 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg07061783 chr6:25882402 NA 0.72 7.44 0.56 1.44e-11 Blood metabolite levels; TGCT cis rs3749237 0.576 rs4241406 chr3:49600426 C/T cg07636037 chr3:49044803 WDR6 0.62 5.75 0.46 6.61e-8 Resting heart rate; TGCT cis rs7666738 0.830 rs11097582 chr4:98772201 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.75 0.46 6.46e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.500 rs35251810 chr12:38577666 T/C cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2153535 0.542 rs1120393 chr6:8486890 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs769267 0.929 rs2905431 chr19:19482882 G/A cg08509172 chr19:19383838 TM6SF2 0.35 4.65 0.39 8.26e-6 Tonsillectomy; TGCT cis rs1008375 0.931 rs6449310 chr4:17575530 T/C cg16339924 chr4:17578868 LAP3 0.82 7.11 0.54 8.13e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9916302 0.851 rs11657899 chr17:37626963 G/A cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs7119 0.651 rs34829483 chr15:77835986 C/T cg27398640 chr15:77910606 LINGO1 -0.28 -5.13 -0.42 1.09e-6 Type 2 diabetes; TGCT cis rs7267979 0.966 rs3002698 chr20:25303379 C/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6570726 0.935 rs388394 chr6:145852689 C/T cg23711669 chr6:146136114 FBXO30 0.69 6.62 0.51 9.73e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6598955 0.543 rs6690461 chr1:26543097 T/A cg04990556 chr1:26633338 UBXN11 0.81 7.35 0.55 2.29e-11 Obesity-related traits; TGCT cis rs57545798 0.500 rs36094016 chr15:100643420 T/C cg05884870 chr15:100654807 ADAMTS17 0.25 4.48 0.37 1.67e-5 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs250677 0.687 rs42364 chr5:148438858 T/A cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs11098499 0.865 rs1112817 chr4:120297800 T/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs2072499 0.966 rs1137703 chr1:156184458 T/C cg24450063 chr1:156163899 SLC25A44 1.14 16.5 0.83 4.43e-33 Testicular germ cell tumor; TGCT cis rs926938 0.560 rs360610 chr1:115393915 T/C cg12756093 chr1:115239321 AMPD1 0.41 5.84 0.46 4.25e-8 Autism; TGCT cis rs9611565 0.592 rs5996039 chr22:41981957 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.15 -0.42 9.88e-7 Vitiligo; TGCT cis rs36093844 0.848 rs2084079 chr11:85590436 C/A cg25872744 chr11:85566296 CCDC83 -0.52 -4.73 -0.39 6.09e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs11122272 0.735 rs2491404 chr1:231512127 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs6952808 0.825 rs12669937 chr7:1939765 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.53 -0.45 1.78e-7 Bipolar disorder and schizophrenia; TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs9467603 0.920 rs68006638 chr6:25710571 G/A cg16898833 chr6:26189333 HIST1H4D 1.37 6.13 0.48 1.1e-8 Intelligence (multi-trait analysis); TGCT cis rs9383153 0.793 rs6937740 chr6:16348080 C/T cg06493612 chr6:15502050 JARID2 0.62 4.91 0.4 2.79e-6 Gambling; TGCT cis rs7681440 0.967 rs920624 chr4:90748195 T/A cg26578617 chr4:90757533 SNCA -0.47 -4.83 -0.4 3.9e-6 Dementia with Lewy bodies; TGCT cis rs2066819 1.000 rs77447765 chr12:56690662 G/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.94 -11.62 -0.72 1.43e-21 Prudent dietary pattern; TGCT cis rs1669338 0.507 rs4685607 chr3:3179400 C/T cg16797762 chr3:3221439 CRBN 0.82 5.38 0.44 3.51e-7 White matter integrity; TGCT cis rs9534288 0.699 rs1409433 chr13:46655501 T/C cg15192986 chr13:46630673 CPB2 -0.53 -6.39 -0.5 3.01e-9 Blood protein levels; TGCT cis rs2760061 0.717 rs708117 chr1:228199902 G/A cg18477163 chr1:228402036 OBSCN 0.34 7.22 0.54 4.65e-11 Diastolic blood pressure; TGCT cis rs6722750 1.000 rs4671552 chr2:64393955 A/G cg22352474 chr2:64371530 PELI1 0.62 5.53 0.44 1.81e-7 Neuroticism; TGCT cis rs1218582 0.774 rs1007170 chr1:154881461 G/A cg09359103 chr1:154839909 KCNN3 -0.71 -15.31 -0.81 2.37e-30 Prostate cancer; TGCT cis rs7017914 0.905 rs2732112 chr8:71927841 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs9527 0.590 rs10883839 chr10:104920341 A/G cg15744005 chr10:104629667 AS3MT -0.41 -4.71 -0.39 6.45e-6 Arsenic metabolism; TGCT cis rs7666738 0.830 rs7659593 chr4:98934823 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs28417716 chr4:98864859 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg13683864 chr3:40499215 RPL14 1.16 12.09 0.74 1.04e-22 Renal cell carcinoma; TGCT cis rs7267979 0.899 rs2179459 chr20:25456141 C/A cg03522245 chr20:25566470 NINL 0.58 6.26 0.49 5.69e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17152411 0.947 rs55674450 chr10:126592153 G/T cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs2012796 1.000 rs8009171 chr14:81820060 G/A cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs9522267 0.535 rs9522305 chr13:112237550 A/G cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg06238570 chr21:40685208 BRWD1 0.7 6.45 0.5 2.3e-9 Cognitive function; TGCT cis rs7937682 0.564 rs9633937 chr11:111372799 C/T cg09085632 chr11:111637200 PPP2R1B 0.54 4.87 0.4 3.35e-6 Primary sclerosing cholangitis; TGCT cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg23283495 chr1:209979779 IRF6 0.68 5.79 0.46 5.34e-8 Cleft lip with or without cleft palate; TGCT cis rs3752962 0.569 rs12451788 chr17:1941048 C/T cg24156229 chr17:1948635 NA 0.37 7.07 0.54 1.02e-10 Itch intensity from mosquito bite; TGCT cis rs34014631 1.000 rs17697908 chr10:103562936 T/G cg22630918 chr10:102748988 C10orf2 0.43 4.8 0.4 4.57e-6 Coronary artery calcification; TGCT cis rs9527 0.569 rs10883801 chr10:104677887 A/C cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs3796352 1.000 rs13072818 chr3:53074263 C/T cg07884673 chr3:53033167 SFMBT1 0.6 6.24 0.49 6.25e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4747241 1.000 rs10509767 chr10:74045917 G/T cg09661010 chr10:73848153 SPOCK2 -0.4 -4.51 -0.38 1.48e-5 Heschl's gyrus morphology; TGCT cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg08859206 chr1:53392774 SCP2 0.35 5.04 0.41 1.62e-6 Monocyte count; TGCT cis rs2439831 1.000 rs561863 chr15:43761352 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT trans rs10506458 1.000 rs73127086 chr12:63415626 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.59 -0.56 6.63e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs950169 0.580 rs1061737 chr15:85183790 G/C cg17173187 chr15:85201210 NMB 0.62 7.09 0.54 8.99e-11 Schizophrenia; TGCT cis rs1552244 0.572 rs3843008 chr3:10173742 C/T cg00149659 chr3:10157352 C3orf10 1.19 7.74 0.57 3.08e-12 Alzheimer's disease; TGCT cis rs8177179 0.967 rs4078166 chr3:133435979 C/A cg24879335 chr3:133465180 TF 0.37 5.03 0.41 1.7e-6 Iron status biomarkers (transferrin levels); TGCT cis rs11167764 1.000 rs10057309 chr5:141479870 T/C cg08523384 chr5:141488047 NDFIP1 -0.25 -5.06 -0.41 1.5e-6 Crohn's disease; TGCT cis rs782590 0.967 rs1975487 chr2:55809054 A/G cg18811423 chr2:55921094 PNPT1 0.64 6.66 0.51 7.97e-10 Metabolic syndrome; TGCT cis rs4285028 0.948 rs35415993 chr3:121669236 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs9926296 0.605 rs6500453 chr16:89858657 C/G cg26513180 chr16:89883248 FANCA 1.05 14.87 0.8 2.47e-29 Vitiligo; TGCT cis rs1043515 0.642 rs8592 chr17:36958065 A/G cg20826740 chr17:37024042 NA 0.42 4.45 0.37 1.92e-5 Height; TGCT cis rs7044106 0.791 rs10985009 chr9:123493039 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.71 -8.1 -0.59 4.39e-13 Hip circumference adjusted for BMI; TGCT cis rs950776 0.518 rs2869055 chr15:78822388 G/C cg06917634 chr15:78832804 PSMA4 -0.89 -8.89 -0.62 6.13e-15 Sudden cardiac arrest; TGCT cis rs7666738 0.830 rs34135615 chr4:99001325 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs13022357 1.000 rs3821301 chr2:160087535 T/G cg00168785 chr2:160142643 WDSUB1 0.46 4.6 0.38 1.04e-5 Sudden cardiac arrest; TGCT cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg11941060 chr3:133502564 NA -0.3 -6.41 -0.5 2.69e-9 Iron status biomarkers; TGCT cis rs6688613 0.685 rs10918599 chr1:166918786 T/C cg07049167 chr1:166818506 POGK 0.25 5.15 0.42 9.89e-7 Refractive astigmatism; TGCT cis rs7611238 0.560 rs57124286 chr3:194992911 A/G cg27323046 chr3:195102265 ACAP2 0.36 4.77 0.39 5.12e-6 Body mass index; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg11965913 chr1:205819406 PM20D1 0.53 7.51 0.56 1.01e-11 Menarche (age at onset); TGCT cis rs9297145 0.724 rs62473013 chr7:98762418 G/T cg05967295 chr7:98741636 SMURF1 0.99 12.81 0.75 1.84e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs4689388 0.926 rs12508672 chr4:6287965 G/A cg25554036 chr4:6271136 WFS1 0.54 7.56 0.56 7.85e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs921968 0.541 rs523305 chr2:219402691 T/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7246657 0.722 rs2909093 chr19:38199462 T/C cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs9913156 0.517 rs7215300 chr17:4608622 T/C cg00122941 chr17:4613640 ARRB2 -0.73 -6.79 -0.52 4.14e-10 Lymphocyte counts; TGCT cis rs13191362 1.000 rs67840803 chr6:163049048 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.92 7.24 0.55 4.11e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2730245 0.527 rs1188971 chr7:158664463 G/T cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs3008870 1.000 rs2755250 chr1:67495283 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.05 11.01 0.7 4.47e-20 Lymphocyte percentage of white cells; TGCT cis rs12497850 0.931 rs7647813 chr3:48833348 G/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg12310025 chr6:25882481 NA -0.66 -5.95 -0.47 2.57e-8 Intelligence (multi-trait analysis); TGCT cis rs826838 1.000 rs11168218 chr12:38884466 A/G cg13010199 chr12:38710504 ALG10B 0.78 6.59 0.51 1.14e-9 Heart rate; TGCT cis rs6087990 0.814 rs2424895 chr20:31335978 C/T cg13636640 chr20:31349939 DNMT3B -0.97 -14.25 -0.79 7.1e-28 Ulcerative colitis; TGCT cis rs7772486 0.790 rs2253307 chr6:146196181 T/G cg05347473 chr6:146136440 FBXO30 0.54 4.98 0.41 2.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2033711 0.870 rs7409473 chr19:58939165 A/G cg04608855 chr19:58913158 NA 0.58 5.76 0.46 6.2e-8 Uric acid clearance; TGCT cis rs7824557 0.510 rs2736297 chr8:11234885 C/G cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.97e-9 Retinal vascular caliber; TGCT cis rs2075371 1.000 rs1421485 chr7:133985181 C/T cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs2777491 0.574 rs1757468 chr15:41743574 T/A cg18705301 chr15:41695430 NDUFAF1 -0.94 -17.35 -0.84 5.64e-35 Ulcerative colitis; TGCT cis rs595982 0.517 rs4801779 chr19:49406651 T/G cg11637076 chr19:49575188 KCNA7 -0.44 -5.42 -0.44 3.01e-7 Red cell distribution width; TGCT cis rs6866344 0.697 rs11743893 chr5:178125194 C/T cg10224037 chr5:178157518 ZNF354A 0.99 8.29 0.6 1.55e-13 Neutrophil percentage of white cells; TGCT cis rs9611565 0.592 rs80477 chr22:42001183 C/T cg17554472 chr22:41940697 POLR3H 0.5 5.23 0.43 6.93e-7 Vitiligo; TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg18765753 chr7:1198926 ZFAND2A -0.55 -6.86 -0.52 2.91e-10 Longevity;Endometriosis; TGCT cis rs1580019 0.961 rs1868776 chr7:32494435 G/T cg06627557 chr7:32535165 LSM5;AVL9 -0.78 -7.29 -0.55 3.16e-11 Cognitive ability; TGCT cis rs9527 0.518 rs10883802 chr10:104680362 C/T cg15744005 chr10:104629667 AS3MT 0.6 4.84 0.4 3.71e-6 Arsenic metabolism; TGCT cis rs826838 1.000 rs826851 chr12:39112639 A/G cg13010199 chr12:38710504 ALG10B -0.68 -5.47 -0.44 2.34e-7 Heart rate; TGCT cis rs736408 0.581 rs3617 chr3:52833805 C/A cg10802521 chr3:52805072 NEK4 -0.66 -7.59 -0.56 6.49e-12 Bipolar disorder; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg01516881 chr6:292596 DUSP22 -0.79 -8.23 -0.59 2.24e-13 Menopause (age at onset); TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs1865760 0.786 rs1436308 chr6:25939567 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.66 6.2 0.49 7.8e-9 Height; TGCT cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg11301795 chr4:187892539 NA -0.33 -4.82 -0.4 4.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.932 rs433352 chr20:25467992 C/T cg14121845 chr20:25566513 NINL -0.5 -5.37 -0.43 3.69e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11098499 0.775 rs10029303 chr4:120286755 T/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs9486719 1.000 rs35487471 chr6:96879715 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs4851254 0.618 rs35300735 chr2:100667829 G/A cg22139774 chr2:100720529 AFF3 -0.44 -4.69 -0.39 7.04e-6 Intelligence (multi-trait analysis); TGCT cis rs992157 0.732 rs10932771 chr2:219170236 A/T cg00012203 chr2:219082015 ARPC2 0.76 7.6 0.56 6.44e-12 Colorectal cancer; TGCT cis rs597539 0.690 rs635529 chr11:68626294 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 7.58 0.56 6.84e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs16866061 0.926 rs17479770 chr2:225335814 A/G cg12698349 chr2:225449008 CUL3 0.94 8.82 0.62 8.6e-15 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs7547997 0.685 rs12734093 chr1:158358660 G/A cg07950803 chr1:158223934 CD1A 0.32 4.78 0.39 4.95e-6 QRS duration; TGCT cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg04772025 chr11:68637568 NA 0.62 6.89 0.53 2.53e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs854765 0.624 rs9902941 chr17:17733760 C/T cg09796270 chr17:17721594 SREBF1 -0.24 -4.52 -0.38 1.42e-5 Total body bone mineral density; TGCT cis rs1865760 0.865 rs1115920 chr6:25954027 A/G cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs56036086 0.938 rs6712 chr22:50637922 C/G cg01548456 chr22:50352384 NA 0.37 4.84 0.4 3.71e-6 Platelet count;Plateletcrit; TGCT trans rs1814175 0.712 rs9665784 chr11:50030617 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs2050392 0.517 rs2771242 chr10:30762973 C/T cg18806716 chr10:30721971 MAP3K8 -0.6 -7.39 -0.55 1.92e-11 Inflammatory bowel disease; TGCT cis rs9910055 0.593 rs58392387 chr17:42297889 A/G cg13607699 chr17:42295918 UBTF 1.14 12.78 0.75 2.21e-24 Total body bone mineral density; TGCT cis rs9394169 0.613 rs4713685 chr6:33774525 C/T cg18005901 chr6:33739558 LEMD2 0.48 5.87 0.47 3.78e-8 Essential tremor; TGCT cis rs1461503 0.966 rs11218910 chr11:122842861 G/A cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT trans rs2469997 0.843 rs2470013 chr8:120360758 G/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg20637647 chr7:64974828 NA 0.94 5.16 0.42 9.35e-7 Diabetic kidney disease; TGCT cis rs675209 0.634 rs1413700 chr6:7216484 G/C cg27097018 chr6:6320614 F13A1 0.36 5.1 0.42 1.24e-6 Urate levels; TGCT cis rs9300255 0.679 rs58809476 chr12:123724880 C/T cg00376283 chr12:123451042 ABCB9 -0.73 -4.95 -0.41 2.41e-6 Neutrophil percentage of white cells; TGCT cis rs3820928 0.839 rs4675123 chr2:227800205 T/C cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.9e-6 Pulmonary function; TGCT cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg19774624 chr17:42201019 HDAC5 -0.84 -8.45 -0.6 6.55e-14 Total body bone mineral density; TGCT cis rs10791323 0.593 rs2156676 chr11:133715791 G/C cg15485101 chr11:133734466 NA 0.4 5.04 0.41 1.59e-6 Childhood ear infection; TGCT cis rs9486715 0.838 rs9386473 chr6:96873341 C/A cg06623918 chr6:96969491 KIAA0776 1.09 15.47 0.81 1.02e-30 Headache; TGCT cis rs9303542 0.559 rs55859232 chr17:46612645 A/G cg25032089 chr17:46643351 HOXB3 0.58 5.48 0.44 2.23e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs9400467 0.537 rs12197886 chr6:111491405 C/G cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs1887596 0.624 rs1331008 chr13:27154435 G/A cg01312412 chr13:27282625 NA 0.29 5.3 0.43 5.16e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs6860806 0.507 rs273915 chr5:131660119 G/C cg24060327 chr5:131705240 SLC22A5 -0.74 -7.98 -0.58 8.3e-13 Breast cancer; TGCT cis rs68170813 0.562 rs11770061 chr7:107071310 A/G cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs4499344 0.633 rs259282 chr19:33163043 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.87 9.25 0.64 8.19e-16 Mean platelet volume; TGCT cis rs6088590 1.000 rs2236270 chr20:33523155 G/T cg06115741 chr20:33292138 TP53INP2 0.68 5.26 0.43 6.2e-7 Coronary artery disease; TGCT cis rs1372520 0.627 rs2583964 chr4:90727218 A/G cg20003494 chr4:90757398 SNCA -0.66 -5.21 -0.42 7.59e-7 Neuroticism; TGCT trans rs7618501 1.000 rs7634902 chr3:49762662 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs2658782 0.547 rs4753453 chr11:93041174 T/G cg15737290 chr11:93063684 CCDC67 1.02 10.75 0.69 1.88e-19 Pulmonary function decline; TGCT cis rs5769765 1.000 rs910800 chr22:50278642 C/T cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.81 0.73 5.03e-22 Schizophrenia; TGCT cis rs6912958 0.500 rs3828759 chr6:87806640 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.69 -6.56 -0.51 1.31e-9 Monocyte percentage of white cells; TGCT cis rs2268241 0.938 rs17879003 chr21:34778527 C/T cg14850771 chr21:34775459 IFNGR2 0.61 5.23 0.43 6.88e-7 Obesity-related traits; TGCT cis rs5417 1.000 rs5417 chr17:7185062 C/A cg25256661 chr17:7137939 DVL2 -0.53 -4.97 -0.41 2.13e-6 Diastolic blood pressure; TGCT cis rs2180341 0.889 rs9321074 chr6:127618019 G/A cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs61677309 1.000 rs12576941 chr11:118158002 A/G cg16594165 chr11:118135105 MPZL2 -0.36 -4.45 -0.37 1.85e-5 Lung cancer in ever smokers; TGCT cis rs2276314 1.000 rs62101367 chr18:33550884 C/T cg19628046 chr18:33552617 C18orf21 0.54 4.62 0.38 9.52e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs7647973 1.000 rs9862534 chr3:49598064 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.82 -0.4 4.16e-6 Menarche (age at onset); TGCT cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg06634786 chr22:41940651 POLR3H 0.89 8.81 0.62 9.46e-15 Vitiligo; TGCT cis rs2980439 0.557 rs2976876 chr8:8318850 T/C cg08975724 chr8:8085496 FLJ10661 0.6 5.45 0.44 2.59e-7 Neuroticism; TGCT cis rs9355610 0.892 rs2247314 chr6:167370230 T/C cg23791538 chr6:167370224 RNASET2 0.64 6.13 0.48 1.07e-8 Graves' disease; TGCT cis rs698813 0.674 rs11680456 chr2:44497544 C/G cg00619915 chr2:44497795 NA -0.24 -5.41 -0.44 3.11e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs9291683 0.935 rs1860910 chr4:10275470 T/G cg11266682 chr4:10021025 SLC2A9 0.45 5.41 0.44 3.11e-7 Bone mineral density; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.43 4.84 0.4 3.75e-6 Lymphocyte counts; TGCT cis rs2404602 0.536 rs17364330 chr15:76765385 A/T cg22467129 chr15:76604101 ETFA -0.47 -5.87 -0.47 3.82e-8 Blood metabolite levels; TGCT cis rs9611519 0.929 rs11090039 chr22:41496800 G/A cg03806693 chr22:41940476 POLR3H -0.67 -6.2 -0.49 7.86e-9 Neuroticism; TGCT cis rs41271951 0.512 rs34761930 chr1:151089523 T/C cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs295140 0.803 rs12469091 chr2:201124735 A/T cg04283868 chr2:201171347 SPATS2L 0.53 5.32 0.43 4.73e-7 QT interval; TGCT cis rs6089829 0.962 rs3746749 chr20:61667333 T/C cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs539096 0.500 rs2367804 chr1:44314266 C/T cg12908607 chr1:44402522 ARTN -0.67 -8.11 -0.59 4.16e-13 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.844 rs2393669 chr6:26503873 C/T cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.673 rs4312757 chr4:9956145 T/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2066819 1.000 rs1274493 chr12:56682371 C/T cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs2637266 1.000 rs2395387 chr10:78357029 T/C cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs7829975 0.711 rs4841051 chr8:8685646 C/T cg08975724 chr8:8085496 FLJ10661 -0.57 -5.14 -0.42 1.04e-6 Mood instability; TGCT cis rs4790312 0.513 rs2232486 chr17:1968983 T/C cg24156229 chr17:1948635 NA -0.36 -5.69 -0.45 8.83e-8 Left atrial antero-posterior diameter; TGCT cis rs899997 0.814 rs28661610 chr15:78985317 G/A cg04896959 chr15:78267971 NA -0.35 -4.82 -0.4 4.14e-6 Coronary artery disease or large artery stroke; TGCT cis rs881375 0.967 rs10733648 chr9:123700779 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.54 0.38 1.34e-5 Rheumatoid arthritis; TGCT cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs861020 0.527 rs614662 chr1:209962419 C/T cg22029157 chr1:209979665 IRF6 -0.48 -4.89 -0.4 3.05e-6 Orofacial clefts; TGCT cis rs832540 0.898 rs2662024 chr5:56257515 T/C cg24531977 chr5:56204891 C5orf35 0.47 4.77 0.39 5.09e-6 Coronary artery disease; TGCT cis rs4843185 0.667 rs4143865 chr16:85716612 T/A cg02644593 chr16:85391138 NA 0.22 4.94 0.41 2.43e-6 Platelet distribution width; TGCT cis rs7809950 0.817 rs2807 chr7:107260778 G/A cg23024343 chr7:107201750 COG5 0.43 6.22 0.49 6.92e-9 Coronary artery disease; TGCT cis rs7267979 1.000 rs6050590 chr20:25384994 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28374715 0.662 rs16971558 chr15:41458619 G/A cg18705301 chr15:41695430 NDUFAF1 -0.77 -10.94 -0.7 6.44e-20 Ulcerative colitis; TGCT cis rs1997103 1.000 rs2331068 chr7:55408220 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9325144 0.581 rs6582564 chr12:38671282 G/A cg26384229 chr12:38710491 ALG10B -0.63 -5.92 -0.47 2.9e-8 Morning vs. evening chronotype; TGCT cis rs6933660 0.800 rs9383893 chr6:151757327 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.55 5.21 0.42 7.75e-7 Menarche (age at onset); TGCT cis rs6952808 0.601 rs3778978 chr7:2159817 A/G cg22963979 chr7:1858916 MAD1L1 -0.4 -6.51 -0.5 1.7e-9 Bipolar disorder and schizophrenia; TGCT cis rs3772130 1.000 rs3772130 chr3:121344140 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.55 4.95 0.41 2.35e-6 Cognitive performance; TGCT cis rs6430585 0.528 rs309167 chr2:136669264 C/T cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs2730245 0.527 rs842700 chr7:158697565 G/A cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs651907 0.557 rs11712748 chr3:101383562 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 11.43 0.72 4.08e-21 Colorectal cancer; TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg08859206 chr1:53392774 SCP2 -0.42 -6.8 -0.52 3.92e-10 Monocyte count; TGCT cis rs9549367 0.789 rs9549716 chr13:113908478 G/A cg18105134 chr13:113819100 PROZ -0.35 -5.94 -0.47 2.68e-8 Platelet distribution width; TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg08859206 chr1:53392774 SCP2 -0.45 -7.37 -0.55 2.16e-11 Monocyte count; TGCT cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg01411255 chr17:61851458 DDX42;CCDC47 1.05 12.3 0.74 3.15e-23 Height; TGCT cis rs2235642 0.928 rs9932984 chr16:1605051 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.29 -4.83 -0.4 3.88e-6 Coronary artery disease; TGCT cis rs1969363 0.509 rs8189633 chr12:38065155 C/G cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Morning vs. evening chronotype; TGCT cis rs61774743 0.557 rs4660192 chr1:41842350 C/T cg01193554 chr1:41846683 NA -0.41 -5.01 -0.41 1.86e-6 Intelligence (multi-trait analysis); TGCT cis rs1784581 0.588 rs9458428 chr6:162424579 A/G cg17173639 chr6:162384350 PARK2 -0.39 -6.43 -0.5 2.49e-9 Itch intensity from mosquito bite; TGCT cis rs508618 0.638 rs479200 chr1:231543780 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.6 -4.92 -0.4 2.64e-6 Red blood cell count; TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg07157834 chr1:205819609 PM20D1 0.43 7.03 0.53 1.25e-10 Menarche (age at onset); TGCT cis rs7208859 0.623 rs9899268 chr17:29150255 T/C cg14008862 chr17:28927542 LRRC37B2 0.8 4.73 0.39 6.11e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs5750830 0.649 rs5757659 chr22:39812409 A/C cg05872129 chr22:39784769 NA -0.97 -10.46 -0.68 9.44e-19 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg02487422 chr3:49467188 NICN1 -0.54 -5.2 -0.42 8.11e-7 Menarche (age at onset); TGCT cis rs644799 0.710 rs3748253 chr11:95519506 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.28 0.6 1.63e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7659604 0.521 rs4833235 chr4:122695136 C/A cg19748678 chr4:122722346 EXOSC9 -0.57 -5.69 -0.45 8.7e-8 Type 2 diabetes; TGCT cis rs9341808 0.667 rs2505929 chr6:80834208 A/G cg08355045 chr6:80787529 NA 0.31 5.31 0.43 4.96e-7 Sitting height ratio; TGCT cis rs12762955 0.561 rs4880744 chr10:1012026 A/G cg20503657 chr10:835505 NA -0.39 -5.09 -0.42 1.29e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg09436375 chr6:42928200 GNMT -0.4 -5.16 -0.42 9.43e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs28595532 0.920 rs116146507 chr4:119749556 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs910316 1.000 rs175425 chr14:75626131 T/C cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.84e-6 Height; TGCT cis rs8180040 0.593 rs10433549 chr3:47031433 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.27 -0.6 1.75e-13 Colorectal cancer; TGCT cis rs2997447 0.688 rs3008431 chr1:26371281 A/G cg19633962 chr1:26362018 EXTL1 -0.69 -5.01 -0.41 1.81e-6 QRS complex (12-leadsum); TGCT cis rs56104184 0.775 rs117016425 chr19:49400216 C/T cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs6560039 1 rs6560039 chr9:90474946 C/T cg24436365 chr6:63940138 NA 0.49 7.46 0.56 1.35e-11 Gait variability; TGCT cis rs7914558 1.000 rs4917996 chr10:104925829 A/C cg05855489 chr10:104503620 C10orf26 0.5 4.47 0.37 1.71e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg11211951 chr8:145729740 GPT -0.22 -5.28 -0.43 5.56e-7 Age at first birth; TGCT cis rs7209700 0.889 rs16941801 chr17:45354543 G/C cg21624342 chr17:45890973 OSBPL7 0.18 5.1 0.42 1.25e-6 IgG glycosylation; TGCT cis rs9368481 0.761 rs4713062 chr6:26948195 A/G cg02458000 chr6:26745757 NA -0.49 -4.48 -0.37 1.66e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs921968 0.613 rs2912737 chr2:219545789 A/G cg02176678 chr2:219576539 TTLL4 -0.33 -4.45 -0.37 1.91e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs2276314 1.000 rs2298716 chr18:33552598 C/T cg05985134 chr18:33552581 C18orf21 0.56 4.94 0.41 2.52e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs6582630 0.502 rs11522899 chr12:38270637 T/C cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT cis rs7954584 0.813 rs12827200 chr12:122451278 G/A cg22618164 chr12:122356400 WDR66 0.53 4.86 0.4 3.55e-6 Mean corpuscular volume; TGCT cis rs1018836 0.608 rs2205150 chr8:91483232 G/A cg16814680 chr8:91681699 NA -0.7 -7.06 -0.54 1.07e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6993813 0.620 rs6984675 chr8:120045227 T/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs753778 0.667 rs10092439 chr8:142210881 C/T cg18755752 chr8:142205143 DENND3 -0.28 -5.11 -0.42 1.19e-6 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs12681288 0.862 rs2004701 chr8:1022287 A/G cg04851639 chr8:1020857 NA -0.37 -6.84 -0.52 3.27e-10 Schizophrenia; TGCT cis rs910316 0.874 rs61980828 chr14:75630378 G/A cg08847533 chr14:75593920 NEK9 -0.94 -10.45 -0.68 1.01e-18 Height; TGCT cis rs938554 0.657 rs9994216 chr4:9984541 G/T cg11266682 chr4:10021025 SLC2A9 0.48 4.91 0.4 2.82e-6 Blood metabolite levels; TGCT cis rs1008375 0.835 rs13122181 chr4:17708815 C/A cg10189774 chr4:17578691 LAP3 -0.54 -4.76 -0.39 5.33e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1670533 1.000 rs641987 chr4:1077542 C/T cg20887711 chr4:1340912 KIAA1530 0.7 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs854765 0.505 rs4506969 chr17:17899839 A/G cg09796270 chr17:17721594 SREBF1 0.23 4.49 0.37 1.59e-5 Total body bone mineral density; TGCT cis rs2013441 1.000 rs9897328 chr17:20174852 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs12931792 0.712 rs56399904 chr16:30166183 C/T cg17640201 chr16:30407289 ZNF48 0.62 5.59 0.45 1.39e-7 Tonsillectomy; TGCT cis rs4499344 0.576 rs259280 chr19:33161452 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.14 0.63 1.5e-15 Mean platelet volume; TGCT trans rs6089829 0.962 rs7267951 chr20:61665979 A/G cg23505145 chr19:12996616 KLF1 0.79 8.07 0.59 5.16e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1215050 0.782 rs6853916 chr4:98653387 C/T cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg06640241 chr16:89574553 SPG7 0.66 6.3 0.49 4.82e-9 Multiple myeloma (IgH translocation); TGCT cis rs1395 0.571 rs114507490 chr2:27527246 T/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.59 7.61 0.56 6.1e-12 Blood metabolite levels; TGCT cis rs10114408 0.959 rs10761292 chr9:96645017 T/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6665290 0.870 rs17600725 chr1:227204231 A/G cg11404489 chr1:228071452 NA -0.19 -4.44 -0.37 1.96e-5 Myeloid white cell count; TGCT cis rs12908161 1.000 rs12911736 chr15:85240008 A/G cg17173187 chr15:85201210 NMB 0.59 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs9611565 0.729 rs505533 chr22:41864216 A/C cg03806693 chr22:41940476 POLR3H 1.03 11.32 0.71 7.58e-21 Vitiligo; TGCT cis rs7617773 0.817 rs936426 chr3:48215253 C/T cg11946769 chr3:48343235 NME6 0.72 6.17 0.48 8.8e-9 Coronary artery disease; TGCT cis rs41307935 0.915 rs34696599 chr1:27203728 A/T cg23921621 chr1:27994728 IFI6 -0.42 -4.59 -0.38 1.06e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs11690462 0.963 rs7588538 chr2:26613329 A/G cg04726446 chr2:26624865 C2orf39 0.42 4.63 0.38 9.27e-6 Coronary artery disease; TGCT cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg19318889 chr4:1322082 MAEA 0.19 4.53 0.38 1.39e-5 Longevity; TGCT cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg22920501 chr2:26401640 FAM59B -0.81 -6.54 -0.51 1.43e-9 Gut microbiome composition (summer); TGCT cis rs12950390 0.853 rs59513807 chr17:45867925 G/A cg24803719 chr17:45855879 NA -0.49 -5.03 -0.41 1.64e-6 IgG glycosylation; TGCT cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg23758822 chr17:41437982 NA 0.72 6.77 0.52 4.51e-10 Menopause (age at onset); TGCT cis rs10501293 0.667 rs993904 chr11:42992769 G/T cg03447554 chr11:43094025 NA 0.44 6.4 0.5 2.93e-9 Cognitive performance; TGCT cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg07424592 chr7:64974309 NA 1.36 8.08 0.59 4.97e-13 Diabetic kidney disease; TGCT cis rs1018836 0.847 rs35409073 chr8:91648036 G/T cg16814680 chr8:91681699 NA -0.89 -9.56 -0.65 1.46e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7975161 0.572 rs4614534 chr12:104597917 C/T cg25273343 chr12:104657179 TXNRD1 0.33 4.95 0.41 2.34e-6 Toenail selenium levels; TGCT cis rs2204008 0.616 rs1607852 chr12:38398125 G/A cg13010199 chr12:38710504 ALG10B 0.61 4.82 0.4 4.12e-6 Bladder cancer; TGCT cis rs7666738 0.830 rs13101766 chr4:98957696 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg16325326 chr1:53192061 ZYG11B 0.62 6.85 0.52 3.05e-10 Monocyte count; TGCT cis rs7659604 0.539 rs11098645 chr4:122729251 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.31 -0.43 4.82e-7 Type 2 diabetes; TGCT cis rs7940866 0.804 rs10894289 chr11:130808685 C/T cg12179176 chr11:130786555 SNX19 0.59 5.81 0.46 4.88e-8 Schizophrenia; TGCT cis rs634534 0.622 rs624273 chr11:65712413 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.52 5.3 0.43 5.03e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs4851266 1.000 rs11691409 chr2:100826165 T/A cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs968451 1.000 rs968451 chr22:39670851 G/T cg17798944 chr22:39715225 SNORD43;RPL3 0.78 6.76 0.52 4.73e-10 Primary biliary cholangitis; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg24675658 chr1:53192096 ZYG11B -0.7 -7.91 -0.58 1.22e-12 Monocyte count; TGCT cis rs7829975 0.511 rs2980426 chr8:8145609 T/C cg15462221 chr8:8086144 FLJ10661 -0.55 -4.74 -0.39 5.87e-6 Mood instability; TGCT cis rs7954584 0.567 rs11612028 chr12:122387872 C/G cg21171335 chr12:122356390 WDR66 0.69 6.98 0.53 1.56e-10 Mean corpuscular volume; TGCT cis rs6770219 0.516 rs11916718 chr3:186141651 A/G cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.46 0.37 1.81e-5 Cerebrospinal T-tau levels; TGCT cis rs2073300 1.000 rs78000067 chr20:23439507 A/G cg09953122 chr20:23471693 CST8 -0.66 -4.64 -0.38 8.6e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT trans rs1814175 0.791 rs9787917 chr11:49937281 C/T cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs6951245 0.872 rs57068908 chr7:1060084 A/C cg03188948 chr7:1209495 NA 0.54 4.48 0.37 1.67e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11190604 1.000 rs11190558 chr10:102209397 C/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6087990 0.806 rs910085 chr20:31383353 T/G cg13636640 chr20:31349939 DNMT3B 1.08 15.49 0.81 8.74e-31 Ulcerative colitis; TGCT trans rs459571 0.804 rs448918 chr9:136885979 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.73 -7.83 -0.58 1.84e-12 Platelet distribution width; TGCT cis rs9916302 0.904 rs612194 chr17:37442707 T/A cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs4824093 0.610 rs60036544 chr22:50264019 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -6.79 -0.52 4.13e-10 Amyotrophic lateral sclerosis (sporadic); TGCT trans rs28735056 1.000 rs59183289 chr18:77631198 A/G cg05926928 chr17:57297772 GDPD1 -0.67 -6.96 -0.53 1.76e-10 Schizophrenia; TGCT cis rs644799 0.965 rs534488 chr11:95562327 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs477895 0.878 rs7478730 chr11:64018827 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 6.93 0.53 2.04e-10 Mean platelet volume; TGCT cis rs6500602 0.893 rs934888 chr16:4462832 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.34 0.49 3.84e-9 Schizophrenia; TGCT cis rs7336332 0.598 rs10220056 chr13:28003781 T/G cg22138327 chr13:27999177 GTF3A 0.83 6.51 0.5 1.67e-9 Weight; TGCT cis rs9914544 0.966 rs1737943 chr17:18841590 A/G cg26378065 chr17:18585709 ZNF286B -0.52 -4.71 -0.39 6.57e-6 Educational attainment (years of education); TGCT cis rs3096299 0.738 rs9929606 chr16:89527537 C/T cg02187348 chr16:89574699 SPG7 0.6 6.01 0.47 1.92e-8 Multiple myeloma (IgH translocation); TGCT cis rs3096299 0.606 rs4785674 chr16:89536613 A/G cg06640241 chr16:89574553 SPG7 0.5 4.51 0.38 1.5e-5 Multiple myeloma (IgH translocation); TGCT cis rs1577917 1.000 rs6933377 chr6:86705255 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 5.39 0.44 3.42e-7 Response to antipsychotic treatment; TGCT cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs3827735 0.599 rs6537835 chr1:115108914 G/A cg12756093 chr1:115239321 AMPD1 0.54 4.62 0.38 9.47e-6 Autism; TGCT cis rs3806843 0.735 rs801180 chr5:140092903 G/T cg19875535 chr5:140030758 IK -0.36 -6.1 -0.48 1.25e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.98 10.67 0.69 2.97e-19 Intelligence (multi-trait analysis); TGCT cis rs17539620 0.624 rs62432746 chr6:154838986 A/G cg20019720 chr6:154832845 CNKSR3 0.57 4.99 0.41 2.02e-6 Lipoprotein (a) levels; TGCT cis rs78456975 0.941 rs11886649 chr2:1567757 A/G cg01028140 chr2:1542097 TPO -0.33 -4.54 -0.38 1.29e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs34467563 0.934 rs1356458 chr8:97404033 C/A cg15747595 chr8:98289880 TSPYL5 -0.41 -4.43 -0.37 2.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg11890956 chr21:40555474 PSMG1 1.1 12.22 0.74 5.02e-23 Cognitive function; TGCT cis rs2404602 0.716 rs1588961 chr15:76752698 A/G cg22467129 chr15:76604101 ETFA -0.57 -6.83 -0.52 3.31e-10 Blood metabolite levels; TGCT cis rs79387448 0.701 rs11465586 chr2:102982709 C/G cg09003973 chr2:102972529 NA 1.39 11.37 0.71 5.75e-21 Gut microbiota (bacterial taxa); TGCT cis rs6952808 0.578 rs6949478 chr7:1841342 A/G cg22963979 chr7:1858916 MAD1L1 0.37 5.99 0.47 2.11e-8 Bipolar disorder and schizophrenia; TGCT cis rs2224391 1.000 rs2753246 chr6:5261845 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -6.04 -0.48 1.66e-8 Height; TGCT cis rs11997175 0.756 rs4739435 chr8:33818818 A/G ch.8.33884649F chr8:33765107 NA 0.34 5.28 0.43 5.56e-7 Body mass index; TGCT cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg03303774 chr4:1407052 NA 0.32 4.9 0.4 2.96e-6 Obesity-related traits; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.52 -5.06 -0.41 1.45e-6 Prudent dietary pattern; TGCT cis rs7772486 0.641 rs9390370 chr6:146357569 C/T cg05347473 chr6:146136440 FBXO30 0.57 5.38 0.44 3.56e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7336332 0.598 rs76790205 chr13:28002885 C/T cg22138327 chr13:27999177 GTF3A 0.83 6.51 0.5 1.67e-9 Weight; TGCT cis rs10186029 0.680 rs4673726 chr2:213981115 T/C cg08319019 chr2:214017104 IKZF2 0.65 5.95 0.47 2.49e-8 Systemic sclerosis; TGCT cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg07424592 chr7:64974309 NA 1.26 7.79 0.57 2.25e-12 Diabetic kidney disease; TGCT cis rs1775715 0.644 rs2799022 chr10:32137198 C/T cg14930904 chr10:32216787 ARHGAP12 0.51 4.91 0.4 2.79e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs1401999 0.714 rs13066518 chr3:183635498 T/A cg01324343 chr3:183735012 ABCC5 0.68 7.95 0.58 1.01e-12 Anterior chamber depth; TGCT cis rs9581857 0.547 rs9581881 chr13:28106637 A/G cg22138327 chr13:27999177 GTF3A 0.77 4.89 0.4 3.05e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs55882075 0.690 rs12374485 chr5:179131395 G/C cg14593053 chr5:179126677 CANX 0.47 5.27 0.43 5.73e-7 Monocyte percentage of white cells; TGCT cis rs1552244 0.572 rs58862481 chr3:10164308 G/A cg00149659 chr3:10157352 C3orf10 1.19 7.35 0.55 2.38e-11 Alzheimer's disease; TGCT cis rs6500602 0.627 rs1641866 chr16:4593040 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 6.96 0.53 1.77e-10 Schizophrenia; TGCT cis rs9300255 0.596 rs10732573 chr12:123743883 G/C cg00376283 chr12:123451042 ABCB9 0.79 6.68 0.51 7.08e-10 Neutrophil percentage of white cells; TGCT cis rs734999 0.588 rs6689711 chr1:2531467 T/C cg18854424 chr1:2615690 NA -0.46 -5.36 -0.43 3.84e-7 Ulcerative colitis; TGCT cis rs4638749 0.953 rs12475415 chr2:108860477 G/A cg06795125 chr2:108905320 SULT1C2 -0.37 -4.69 -0.39 6.95e-6 Blood pressure; TGCT cis rs12549902 0.966 rs10504042 chr8:41515993 G/A cg21772509 chr8:41503840 NKX6-3 0.85 9.62 0.65 1.04e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs9549367 0.789 rs34568744 chr13:113894564 G/T cg00898013 chr13:113819073 PROZ -0.4 -4.98 -0.41 2.13e-6 Platelet distribution width; TGCT trans rs731174 0.559 rs66536721 chr1:38195582 A/G cg19725343 chr19:51830960 IGLON5 -0.62 -6.99 -0.53 1.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs12210905 0.688 rs12193557 chr6:27435944 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg04944784 chr2:26401820 FAM59B 0.77 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs9926296 0.744 rs164749 chr16:89708224 A/C cg03388025 chr16:89894329 SPIRE2 -0.31 -4.93 -0.41 2.55e-6 Vitiligo; TGCT cis rs7589728 0.858 rs79992736 chr2:88530575 A/C cg04511125 chr2:88470314 THNSL2 0.63 5.13 0.42 1.08e-6 Plasma clusterin levels; TGCT cis rs2710642 0.777 rs2539987 chr2:63142864 A/G cg17519650 chr2:63277830 OTX1 0.58 5.29 0.43 5.47e-7 LDL cholesterol levels;LDL cholesterol; TGCT cis rs7647973 0.559 rs9586 chr3:49213637 C/T cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.51 -0.38 1.48e-5 Menarche (age at onset); TGCT cis rs12579753 0.917 rs11115032 chr12:82205073 T/C cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg03060546 chr3:49711283 APEH 0.5 4.7 0.39 6.82e-6 Menarche (age at onset); TGCT cis rs72945132 0.882 rs7937984 chr11:70144254 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7267979 1.000 rs2387884 chr20:25379069 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs941408 0.963 rs1640268 chr19:2791469 T/C cg19676328 chr12:49525230 TUBA1B -0.77 -7.92 -0.58 1.16e-12 Total cholesterol levels; TGCT cis rs12681287 0.547 rs13267858 chr8:87510871 G/A cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg05738196 chr6:26577821 NA 0.87 11.3 0.71 8.47e-21 Intelligence (multi-trait analysis); TGCT trans rs10506458 0.915 rs2013050 chr12:63394310 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs10927875 0.662 rs848309 chr1:16308447 T/C cg22431228 chr1:16359049 CLCNKA -0.26 -5.43 -0.44 2.79e-7 Dilated cardiomyopathy; TGCT trans rs7726839 0.574 rs72707007 chr5:661856 T/C cg25482853 chr8:67687455 SGK3 1.21 10.93 0.7 6.89e-20 Obesity-related traits; TGCT cis rs1801251 1.000 rs6746294 chr2:233583050 C/G cg25237894 chr2:233734115 C2orf82 -0.3 -5.36 -0.43 3.83e-7 Coronary artery disease; TGCT cis rs9393777 0.920 rs35869525 chr6:26946687 C/T cg12315302 chr6:26189340 HIST1H4D 0.93 4.48 0.37 1.71e-5 Intelligence (multi-trait analysis); TGCT cis rs7086627 0.515 rs11202957 chr10:82209592 A/G cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs4654899 0.758 rs10218584 chr1:21474480 C/G cg01072550 chr1:21505969 NA 0.57 9.41 0.65 3.42e-16 Superior frontal gyrus grey matter volume; TGCT cis rs3784262 1.000 rs12903474 chr15:58276747 A/C cg12031962 chr15:58353849 ALDH1A2 0.49 7.56 0.56 7.97e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1975974 0.872 rs66502681 chr17:21722119 T/A cg18423549 chr17:21743878 NA -0.54 -5.15 -0.42 1.01e-6 Psoriasis; TGCT cis rs6582630 0.519 rs1851130 chr12:38507819 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.87 0.58 1.53e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs6570726 0.935 rs392014 chr6:145843691 A/C cg23711669 chr6:146136114 FBXO30 0.67 6.26 0.49 5.65e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.649 rs2145318 chr6:26496603 T/A cg09904177 chr6:26538194 HMGN4 0.59 5.56 0.45 1.56e-7 Intelligence (multi-trait analysis); TGCT cis rs7447593 0.518 rs4074995 chr5:176797343 C/T cg16006841 chr5:176797999 RGS14 0.71 12.13 0.74 8.0700000000000006e-23 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg21280719 chr6:42927975 GNMT -0.37 -4.56 -0.38 1.22e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs244731 0.959 rs7721671 chr5:176630984 A/G cg16006841 chr5:176797999 RGS14 -0.53 -6.95 -0.53 1.88e-10 Urate levels in lean individuals; TGCT cis rs2996428 0.667 rs7538067 chr1:3761772 C/T cg13057898 chr1:3703894 LRRC47 0.21 4.62 0.38 9.46e-6 Red cell distribution width; TGCT cis rs9653442 0.564 rs11687586 chr2:100789346 A/G cg22139774 chr2:100720529 AFF3 -0.35 -5.55 -0.45 1.63e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs12497850 0.829 rs8926 chr3:49052785 T/A cg07636037 chr3:49044803 WDR6 0.96 10.9 0.7 8.39e-20 Parkinson's disease; TGCT cis rs9467773 1.000 rs9357010 chr6:26527945 C/G cg09904177 chr6:26538194 HMGN4 0.66 6.83 0.52 3.37e-10 Intelligence (multi-trait analysis); TGCT cis rs10927875 0.596 rs1806990 chr1:16129377 G/A cg21385522 chr1:16154831 NA -0.96 -15.71 -0.82 2.84e-31 Dilated cardiomyopathy; TGCT cis rs1862618 0.525 rs832403 chr5:56265992 G/T cg20203395 chr5:56204925 C5orf35 0.64 4.73 0.39 6.02e-6 Initial pursuit acceleration; TGCT cis rs9611519 0.558 rs8137906 chr22:41442566 A/G cg13695892 chr22:41940480 POLR3H -0.56 -5.29 -0.43 5.29e-7 Neuroticism; TGCT cis rs12971120 0.947 rs3764509 chr18:72167124 C/G cg26446133 chr18:72167187 CNDP2 -0.4 -7.7 -0.57 3.64e-12 Refractive error; TGCT cis rs4689388 0.926 rs3889821 chr4:6282596 C/T cg14416269 chr4:6271139 WFS1 0.38 5.23 0.42 7.12e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg17328964 chr8:145687451 CYHR1 0.45 6.66 0.51 7.93e-10 Age at first birth; TGCT cis rs2980439 0.783 rs2955587 chr8:8098079 A/G cg15556689 chr8:8085844 FLJ10661 0.88 9.13 0.63 1.6e-15 Neuroticism; TGCT cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT trans rs1005277 0.579 rs2983343 chr10:38383332 A/G cg17830980 chr10:43048298 ZNF37B -0.85 -10.98 -0.7 5.08e-20 Extrinsic epigenetic age acceleration; TGCT cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg16049864 chr8:95962084 TP53INP1 -0.73 -10.16 -0.67 5.23e-18 Type 2 diabetes; TGCT cis rs2120019 0.938 rs1867150 chr15:75321139 T/C cg17294928 chr15:75287854 SCAMP5 -0.79 -6.27 -0.49 5.46e-9 Blood trace element (Zn levels); TGCT cis rs11172134 0.508 rs1800175 chr12:57561379 G/T cg19258868 chr12:57585184 LRP1 -0.32 -6.22 -0.49 6.94e-9 Urate levels in overweight individuals; TGCT cis rs986417 1.000 rs1313249 chr14:60881997 C/G cg27398547 chr14:60952738 C14orf39 -1.49 -10.81 -0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs3008870 0.958 rs12131222 chr1:67438535 A/T cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT trans rs7615952 0.866 rs11922276 chr3:125631326 G/T cg07211511 chr3:129823064 LOC729375 -0.45 -7.36 -0.55 2.2e-11 Blood pressure (smoking interaction); TGCT cis rs1997103 1.000 rs6957984 chr7:55397331 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs709400 0.598 rs11627529 chr14:104004557 C/T cg12935359 chr14:103987150 CKB -0.37 -5.54 -0.45 1.73e-7 Body mass index; TGCT cis rs7829975 0.560 rs4841013 chr8:8552013 A/G cg06636001 chr8:8085503 FLJ10661 -0.61 -5.31 -0.43 4.81e-7 Mood instability; TGCT cis rs9467711 0.606 rs9379875 chr6:26444732 C/T cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11785400 0.793 rs9297972 chr8:143723660 C/T cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs1008375 1.000 rs12648232 chr4:17612537 C/T cg16339924 chr4:17578868 LAP3 -0.66 -5.6 -0.45 1.34e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10984561 0.748 rs12236090 chr9:122250920 A/G cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs2439831 0.702 rs2467402 chr15:44024490 A/C cg11515196 chr15:44829065 EIF3J 0.73 4.47 0.37 1.74e-5 Lung cancer in ever smokers; TGCT cis rs921968 0.643 rs600057 chr2:219456737 A/G cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs4845570 1.000 rs7542898 chr1:151753622 T/G cg07092448 chr1:151763213 TDRKH -1.12 -8.18 -0.59 2.84e-13 Coronary artery disease; TGCT trans rs8073060 0.592 rs225306 chr17:33920036 A/C cg19694781 chr19:47549865 TMEM160 0.38 7.43 0.56 1.53e-11 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.81 7.61 0.56 5.98e-12 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg04025307 chr7:1156635 C7orf50 0.2 4.67 0.39 7.62e-6 Longevity;Endometriosis; TGCT cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.63 -0.38 9.09e-6 Bipolar disorder; TGCT cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg12386194 chr3:101231763 SENP7 0.52 5.01 0.41 1.81e-6 Colorectal cancer; TGCT cis rs6500596 0.570 rs8055628 chr16:4447477 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.36 5.31 0.43 4.92e-7 Schizophrenia; TGCT cis rs9303401 0.659 rs1864754 chr17:56688789 G/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.62 -6.32 -0.49 4.18e-9 Cognitive test performance; TGCT trans rs6089829 0.962 rs6062778 chr20:61663959 A/G cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs12908161 0.920 rs12904605 chr15:85201419 T/C cg17173187 chr15:85201210 NMB 0.6 6.74 0.52 5.37e-10 Schizophrenia; TGCT cis rs6121246 0.567 rs6060344 chr20:30207316 A/G cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs4665809 1.000 rs4665298 chr2:26256378 G/A cg25036284 chr2:26402008 FAM59B -0.54 -4.71 -0.39 6.53e-6 Gut microbiome composition (summer); TGCT cis rs910316 0.673 rs2012627 chr14:75443103 C/T cg08847533 chr14:75593920 NEK9 0.83 8.56 0.61 3.57e-14 Height; TGCT cis rs4665809 1.000 rs4665817 chr2:26305167 G/A cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs4478858 0.684 rs7549343 chr1:31752260 A/G cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs9733 0.596 rs7529998 chr1:150662531 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs7781977 0.960 rs17732497 chr7:50336073 C/A cg14216940 chr7:50343131 IKZF1 0.4 4.51 0.38 1.49e-5 IgG glycosylation; TGCT cis rs2404602 0.967 rs12148805 chr15:76800659 G/A cg22467129 chr15:76604101 ETFA -0.51 -5.89 -0.47 3.45e-8 Blood metabolite levels; TGCT cis rs425277 0.585 rs3128294 chr1:2065343 G/C cg03732007 chr1:2071316 PRKCZ -0.28 -6.32 -0.49 4.33e-9 Height; TGCT cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs254779 0.538 rs254776 chr5:88006893 G/C cg22951263 chr5:87985283 NA -0.55 -4.93 -0.4 2.63e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6141769 0.542 rs4425162 chr20:31312916 A/G cg13636640 chr20:31349939 DNMT3B -0.52 -4.54 -0.38 1.34e-5 Subjective well-being; TGCT cis rs2404602 0.647 rs907594 chr15:77197745 C/A cg22467129 chr15:76604101 ETFA 0.48 4.86 0.4 3.42e-6 Blood metabolite levels; TGCT cis rs7833790 0.724 rs72603871 chr8:82754460 C/G cg23324259 chr8:82754387 SNX16 0.62 4.71 0.39 6.47e-6 Diastolic blood pressure; TGCT cis rs514406 0.861 rs12038438 chr1:53230581 A/T cg08736216 chr1:53307985 ZYG11A 0.26 5.07 0.41 1.43e-6 Monocyte count; TGCT cis rs1371867 0.846 rs1660328 chr8:101303450 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs7106204 0.748 rs28552633 chr11:24207518 A/C ch.11.24196551F chr11:24239977 NA 0.47 4.45 0.37 1.91e-5 Response to Homoharringtonine (cytotoxicity); TGCT cis rs11577318 0.853 rs7541333 chr1:26622889 C/T cg04990556 chr1:26633338 UBXN11 -0.58 -5.37 -0.43 3.68e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs10782582 0.609 rs111914775 chr1:76319036 C/T cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs7296418 0.518 rs28825193 chr12:123878262 T/C cg00376283 chr12:123451042 ABCB9 0.63 5.46 0.44 2.47e-7 Platelet count; TGCT cis rs2013441 1.000 rs17759959 chr17:20024095 A/G cg18979559 chr17:20280153 CCDC144C 0.48 5.06 0.41 1.48e-6 Obesity-related traits; TGCT cis rs6684514 1.000 rs10752615 chr1:156248609 T/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.25 -0.43 6.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.526 rs9688946 chr6:26367445 C/A cg15659132 chr6:26577336 NA -0.5 -5.05 -0.41 1.53e-6 Intelligence (multi-trait analysis); TGCT cis rs7584330 0.910 rs12465081 chr2:238401784 A/G cg14458575 chr2:238380390 NA 0.38 5.61 0.45 1.25e-7 Prostate cancer; TGCT cis rs7208859 0.573 rs73267829 chr17:29003939 G/A cg14008862 chr17:28927542 LRRC37B2 0.85 5.11 0.42 1.2e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7428 0.527 rs1554110 chr2:85547963 C/T cg24342717 chr2:85555507 TGOLN2 -0.49 -7.81 -0.57 2.04e-12 Ear protrusion; TGCT trans rs34421088 0.560 rs11780851 chr8:11401116 G/A cg15556689 chr8:8085844 FLJ10661 -0.74 -7.04 -0.53 1.14e-10 Neuroticism; TGCT cis rs9910055 0.659 rs186603 chr17:42207884 C/T cg13607699 chr17:42295918 UBTF -0.59 -5.38 -0.43 3.65e-7 Total body bone mineral density; TGCT cis rs904251 0.766 rs1757175 chr6:37486694 T/C cg25019722 chr6:37503610 NA -0.51 -7.0 -0.53 1.43e-10 Cognitive performance; TGCT cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.87 0.47 3.73e-8 Alzheimer's disease; TGCT cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.55 -5.1 -0.42 1.21e-6 Bipolar disorder; TGCT cis rs28735056 0.933 rs72980085 chr18:77631679 A/C cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs909002 0.800 rs3753613 chr1:32082000 C/T cg11573219 chr1:32083031 HCRTR1 0.43 5.59 0.45 1.41e-7 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.59 -5.71 -0.46 7.79e-8 Intelligence (multi-trait analysis); TGCT cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg01411255 chr17:61851458 DDX42;CCDC47 1.12 14.83 0.8 3.07e-29 Height; TGCT cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg18252515 chr7:66147081 NA 1.25 7.62 0.56 5.7e-12 Diabetic kidney disease; TGCT cis rs10875595 0.836 rs56756237 chr5:140678342 T/C cg20560182 chr5:140700478 TAF7 -0.64 -4.78 -0.39 4.77e-6 Pulmonary function decline; TGCT cis rs9303401 0.659 rs35928756 chr17:56702652 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7584330 0.704 rs7598954 chr2:238364776 C/T cg14458575 chr2:238380390 NA 0.59 8.88 0.62 6.18e-15 Prostate cancer; TGCT cis rs7666738 0.753 rs35146453 chr4:98902278 A/G cg05340658 chr4:99064831 C4orf37 0.51 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9942416 0.630 rs253388 chr5:74975912 A/G cg19683494 chr5:74908142 NA -0.6 -6.34 -0.49 3.83e-9 Age-related disease endophenotypes; TGCT cis rs7666738 0.830 rs13125537 chr4:98978428 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7100689 0.577 rs4934038 chr10:82057334 C/A cg01528321 chr10:82214614 TSPAN14 0.7 6.78 0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs11112613 0.713 rs55646142 chr12:105949557 G/A cg03607813 chr12:105948248 NA 0.52 6.0 0.47 2.03e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7412746 0.658 rs6660845 chr1:150841066 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 4.75 0.39 5.55e-6 Melanoma; TGCT cis rs7120118 0.517 rs56177220 chr11:47328377 C/T cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.26e-7 HDL cholesterol; TGCT cis rs899997 0.953 rs11633519 chr15:78999552 A/G cg00061860 chr15:78953028 NA -0.29 -4.87 -0.4 3.33e-6 Coronary artery disease or large artery stroke; TGCT cis rs12142240 0.698 rs72677600 chr1:46834449 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.78 0.46 5.69e-8 Menopause (age at onset); TGCT cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs10927875 0.597 rs61782184 chr1:16150976 G/A cg14742211 chr1:16348397 CLCNKA -0.19 -4.65 -0.38 8.54e-6 Dilated cardiomyopathy; TGCT cis rs10782582 0.609 rs78748984 chr1:76340467 G/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs1218582 0.772 rs6656435 chr1:154876869 G/A cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs7927592 0.513 rs7950129 chr11:68202903 A/G cg16797656 chr11:68205561 LRP5 0.28 5.13 0.42 1.08e-6 Total body bone mineral density; TGCT cis rs938554 0.571 rs7696092 chr4:10025320 C/A cg00071950 chr4:10020882 SLC2A9 0.53 4.79 0.4 4.69e-6 Blood metabolite levels; TGCT cis rs17253792 0.822 rs79262019 chr14:56092704 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs933688 1.000 rs2839728 chr5:90727412 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.58 0.69 4.88e-19 Smoking behavior; TGCT cis rs12220898 0.679 rs7082585 chr10:50486747 G/T cg06072769 chr10:50146962 WDFY4 0.39 5.18 0.42 8.72e-7 Inflammatory biomarkers; TGCT cis rs2562456 0.833 rs62110429 chr19:21613786 C/T cg25650185 chr19:21324782 ZNF431 -0.58 -4.55 -0.38 1.25e-5 Pain; TGCT trans rs1005277 0.563 rs2505216 chr10:38482830 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.51 0.61 4.68e-14 Extrinsic epigenetic age acceleration; TGCT cis rs4253772 0.591 rs6007795 chr22:46686792 C/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 5.27 0.43 5.83e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs6992820 0.902 rs6999008 chr8:56768236 G/A cg06880721 chr8:56792545 LYN -0.72 -5.98 -0.47 2.25e-8 Mean platelet volume; TGCT cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs9393692 0.552 rs806789 chr6:26229161 C/A cg05868516 chr6:26286170 HIST1H4H 0.52 5.02 0.41 1.79e-6 Educational attainment; TGCT cis rs3829109 0.534 rs563 chr9:139296485 C/T cg13741927 chr9:139327495 INPP5E 0.26 5.51 0.44 2.03e-7 Peak insulin response;Acute insulin response; TGCT cis rs10883723 0.775 rs2296579 chr10:104241375 A/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs9473924 0.505 rs7756058 chr6:50904438 G/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs4746818 0.892 rs10823298 chr10:70867083 T/C cg11621586 chr10:70884670 VPS26A 1.15 9.19 0.64 1.14e-15 Left atrial antero-posterior diameter; TGCT cis rs2486288 0.656 rs9921035 chr15:45546660 C/T cg26924012 chr15:45694286 SPATA5L1 -0.74 -7.8 -0.57 2.23e-12 Glomerular filtration rate; TGCT cis rs35306767 0.714 rs67696450 chr10:1090684 C/T cg20503657 chr10:835505 NA 0.6 6.93 0.53 2e-10 Eosinophil percentage of granulocytes; TGCT cis rs554111 0.593 rs7540023 chr1:21310092 T/C cg01072550 chr1:21505969 NA 0.36 5.43 0.44 2.9e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs5769765 0.778 rs4574208 chr22:50256738 C/T cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.32 0.71 7.61e-21 Schizophrenia; TGCT cis rs259282 0.532 rs259283 chr19:33163103 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 1.06 12.87 0.76 1.38e-24 Schizophrenia; TGCT cis rs317689 0.513 rs317678 chr12:69692166 C/G cg20891283 chr12:69753455 YEATS4 0.56 5.13 0.42 1.1e-6 Response to diuretic therapy; TGCT cis rs9300255 0.596 rs10734900 chr12:123743445 G/A cg00376283 chr12:123451042 ABCB9 0.79 6.68 0.51 7.08e-10 Neutrophil percentage of white cells; TGCT cis rs910316 0.967 rs175498 chr14:75536369 G/A cg08847533 chr14:75593920 NEK9 -0.95 -10.3 -0.68 2.36e-18 Height; TGCT cis rs1862618 0.641 rs170733 chr5:56249251 A/G cg20203395 chr5:56204925 C5orf35 0.52 4.77 0.39 5e-6 Initial pursuit acceleration; TGCT cis rs208520 0.954 rs72884027 chr6:66995044 T/G cg07460842 chr6:66804631 NA 0.8 6.98 0.53 1.61e-10 Exhaled nitric oxide output; TGCT trans rs1814175 0.817 rs1621090 chr11:49895868 C/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.34 -0.55 2.4e-11 Height; TGCT cis rs12497850 0.931 rs9311433 chr3:48863835 T/C cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs3008870 1.000 rs12117131 chr1:67451922 C/T cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Vitiligo; TGCT cis rs9326248 1.000 rs7107152 chr11:117056080 C/T cg11861562 chr11:117069780 TAGLN -0.26 -4.62 -0.38 9.44e-6 Blood protein levels; TGCT cis rs1691799 0.899 rs1168299 chr12:66736074 C/G cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.87e-9 White blood cell count (basophil); TGCT cis rs35146811 0.961 rs11771139 chr7:99736059 C/T cg22906224 chr7:99728672 NA 0.5 4.68 0.39 7.42e-6 Coronary artery disease; TGCT cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg23205692 chr1:25664452 TMEM50A 0.47 4.88 0.4 3.15e-6 Erythrocyte sedimentation rate; TGCT cis rs7666738 0.830 rs10034330 chr4:99064849 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.31 0.43 4.87e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1153858 1.000 rs2453541 chr15:45645378 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg06481639 chr22:41940642 POLR3H -0.74 -6.51 -0.5 1.71e-9 Vitiligo; TGCT cis rs7937682 0.924 rs875257 chr11:111530453 A/G cg09085632 chr11:111637200 PPP2R1B -1.12 -11.81 -0.73 4.86e-22 Primary sclerosing cholangitis; TGCT cis rs9611565 0.568 rs5751159 chr22:42175365 G/A cg06481639 chr22:41940642 POLR3H 0.53 4.54 0.38 1.29e-5 Vitiligo; TGCT cis rs2013441 0.931 rs4925089 chr17:20064784 A/T cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg09222892 chr1:25734099 RHCE -0.42 -6.88 -0.53 2.6200000000000003e-10 Erythrocyte sedimentation rate; TGCT cis rs1801251 1.000 rs283480 chr2:233648742 G/A cg25237894 chr2:233734115 C2orf82 0.28 4.82 0.4 4.05e-6 Coronary artery disease; TGCT cis rs7552404 0.731 rs17650138 chr1:76398887 C/T cg22875332 chr1:76189707 ACADM -0.75 -7.0 -0.53 1.42e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs589448 0.902 rs528974 chr12:69765918 A/T cg14784868 chr12:69753453 YEATS4 0.89 10.48 0.69 8.4e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs7666738 0.791 rs10022061 chr4:98926821 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10858047 0.883 rs6695699 chr1:115209951 C/A cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs40363 1.000 rs1690443 chr16:3517787 C/G cg22508957 chr16:3507546 NAT15 0.56 5.25 0.43 6.33e-7 Tuberculosis; TGCT cis rs854765 0.547 rs4584886 chr17:17896205 C/T cg04398451 chr17:18023971 MYO15A -0.33 -5.18 -0.42 8.63e-7 Total body bone mineral density; TGCT cis rs12477438 0.798 rs1453561 chr2:99613924 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.69 -5.87 -0.47 3.64e-8 Chronic sinus infection; TGCT cis rs6714788 0.565 rs7558817 chr2:100654482 C/A cg07810366 chr2:100720526 AFF3 -0.36 -5.07 -0.41 1.43e-6 Intelligence (multi-trait analysis); TGCT cis rs12188164 0.610 rs6555242 chr5:416546 A/C cg13013644 chr5:502571 SLC9A3 -0.27 -4.45 -0.37 1.91e-5 Cystic fibrosis severity; TGCT cis rs7714584 1.000 rs76872831 chr5:150171559 A/G cg22134413 chr5:150180641 NA 1.11 7.3 0.55 3.05e-11 Crohn's disease; TGCT cis rs7666738 0.570 rs1921415 chr4:99093804 C/T cg05340658 chr4:99064831 C4orf37 0.44 4.72 0.39 6.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7646881 0.504 rs4264773 chr3:158463225 G/T cg18349298 chr3:158450550 RARRES1 0.42 4.44 0.37 1.97e-5 Tetralogy of Fallot; TGCT cis rs4629710 0.645 rs34601891 chr6:131551238 C/T cg12606694 chr6:131520996 AKAP7 0.39 4.63 0.38 9.14e-6 Multiple myeloma (IgH translocation); TGCT cis rs67478160 0.654 rs1997913 chr14:104213960 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.37 -0.5 3.33e-9 Schizophrenia; TGCT cis rs13108904 0.539 rs13141169 chr4:1340353 C/T cg13395646 chr4:1353034 KIAA1530 -0.57 -7.74 -0.57 2.98e-12 Obesity-related traits; TGCT cis rs986417 1.000 rs9989167 chr14:60942374 T/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs3845702 0.736 rs6433818 chr2:180810264 A/T cg01881094 chr2:180872142 CWC22 -1.03 -6.51 -0.5 1.72e-9 Schizophrenia; TGCT cis rs1008375 0.900 rs1003413 chr4:17582442 C/T cg16339924 chr4:17578868 LAP3 -0.84 -7.17 -0.54 5.96e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1075232 1.000 rs72722847 chr15:31682346 C/T cg01030201 chr15:31746330 NA -1.1 -5.4 -0.44 3.27e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs7267979 1.000 rs2424704 chr20:25273929 A/G cg03522245 chr20:25566470 NINL 0.62 6.56 0.51 1.34e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9948 0.655 rs62156210 chr2:97393736 A/T cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT trans rs4919669 0.668 rs7086898 chr10:104386152 A/G cg24066601 chr6:26271455 HIST1H3G 0.66 6.81 0.52 3.7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs6088580 0.634 rs4911421 chr20:32998948 T/C cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs7698623 0.850 rs3886171 chr4:88800053 A/G cg27387453 chr4:88533842 DSPP -0.6 -4.53 -0.38 1.35e-5 Cardiovascular disease risk factors; TGCT cis rs9818758 0.607 rs35673421 chr3:49139406 G/A cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4478858 0.684 rs12121165 chr1:31725542 G/A cg00250761 chr1:31883323 NA -0.28 -5.01 -0.41 1.86e-6 Alcohol dependence; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg26338869 chr17:61819248 STRADA 0.53 4.92 0.4 2.71e-6 Prudent dietary pattern; TGCT cis rs9291683 0.645 rs11557743 chr4:10118377 C/G cg11266682 chr4:10021025 SLC2A9 -0.44 -5.17 -0.42 9.18e-7 Bone mineral density; TGCT cis rs7714584 1.000 rs73282255 chr5:150223647 A/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs7208859 0.524 rs77498725 chr17:29063986 C/T cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg25767906 chr1:53392781 SCP2 -0.59 -7.49 -0.56 1.12e-11 Monocyte count; TGCT cis rs2224391 1.000 rs9504370 chr6:5261601 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.8 -6.12 -0.48 1.13e-8 Height; TGCT cis rs7635838 0.587 rs347591 chr3:11290122 G/T cg00170343 chr3:11313890 ATG7 0.65 6.52 0.51 1.63e-9 HDL cholesterol; TGCT cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs10751667 0.666 rs10902235 chr11:938892 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs9527 0.590 rs7088200 chr10:104793235 G/A cg04362960 chr10:104952993 NT5C2 0.66 5.57 0.45 1.48e-7 Arsenic metabolism; TGCT cis rs6684514 1.000 rs12121805 chr1:156257876 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10088262 0.629 rs12549683 chr8:124798276 G/C cg20713898 chr8:124780851 FAM91A1 -0.84 -7.19 -0.54 5.3e-11 Pancreatic cancer; TGCT cis rs11250098 0.583 rs7000276 chr8:10804843 G/A cg21775007 chr8:11205619 TDH -0.57 -5.36 -0.43 3.87e-7 Morning vs. evening chronotype; TGCT cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg20203395 chr5:56204925 C5orf35 0.75 5.74 0.46 6.81e-8 Initial pursuit acceleration; TGCT trans rs2688608 0.967 rs2675663 chr10:75660270 T/G cg13918328 chr10:52500089 ASAH2B 0.64 6.65 0.51 8.42e-10 Inflammatory bowel disease; TGCT cis rs3784262 0.669 rs4646595 chr15:58302341 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.83e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.64 0.38 8.63e-6 Prudent dietary pattern; TGCT cis rs11731606 0.508 rs7677981 chr4:95299736 C/T cg00507259 chr4:95128692 SMARCAD1 0.63 4.72 0.39 6.14e-6 Mean platelet volume; TGCT cis rs7267979 1.000 rs6050573 chr20:25366065 C/G cg03522245 chr20:25566470 NINL 0.61 6.52 0.51 1.62e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs911263 0.603 rs61985136 chr14:68769199 C/T cg18825221 chr14:68749962 RAD51L1 0.22 4.44 0.37 1.97e-5 Primary biliary cholangitis; TGCT cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg27286337 chr10:134555280 INPP5A 0.4 4.91 0.4 2.76e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3087591 1.000 rs2854331 chr17:29711728 G/A cg24425628 chr17:29625626 OMG;NF1 -0.46 -6.97 -0.53 1.65e-10 Hip circumference; TGCT cis rs6912958 0.559 rs1201409 chr6:88055264 T/C cg08069147 chr6:88032118 GJB7;C6orf162 0.69 7.07 0.54 1.02e-10 Monocyte percentage of white cells; TGCT cis rs875971 0.792 rs6971752 chr7:65737986 G/A cg11764359 chr7:65958608 NA -0.57 -5.12 -0.42 1.12e-6 Aortic root size; TGCT cis rs245880 0.740 rs245886 chr7:29189336 G/T cg17163760 chr7:29186267 CPVL -0.44 -5.54 -0.45 1.73e-7 Warfarin maintenance dose; TGCT cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg10862848 chr6:42927986 GNMT -0.39 -4.72 -0.39 6.22e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs681343 0.746 rs633372 chr19:49209226 G/A cg00822241 chr19:49201468 FUT2 0.28 4.53 0.38 1.36e-5 Lung adenocarcinoma;Primary sclerosing cholangitis;Childhood ear infection; TGCT cis rs2243480 1.000 rs778729 chr7:65824419 T/C cg20637647 chr7:64974828 NA 0.92 5.09 0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs13102973 0.611 rs4298187 chr4:135886186 G/A cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs4654899 0.865 rs7541923 chr1:21403582 G/C cg01072550 chr1:21505969 NA -0.46 -6.77 -0.52 4.55e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4786125 0.555 rs7196838 chr16:6920457 A/G cg03623568 chr16:6915990 A2BP1 -0.45 -6.68 -0.51 7.28e-10 Heart rate variability traits (SDNN); TGCT cis rs6570726 0.935 rs391820 chr6:145821284 C/T cg23711669 chr6:146136114 FBXO30 0.69 6.22 0.49 6.89e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769707 0.839 rs73176988 chr22:49989649 G/T cg10356904 chr22:49881777 NA -0.23 -4.68 -0.39 7.54e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs877282 1.000 rs71494928 chr10:769134 A/G cg17470449 chr10:769945 NA 0.35 5.21 0.42 7.51e-7 Uric acid levels; TGCT cis rs858239 0.899 rs5850 chr7:23314547 C/T cg05602783 chr7:23145260 KLHL7 -0.7 -5.55 -0.45 1.63e-7 Cerebrospinal fluid biomarker levels; TGCT trans rs11722228 0.508 rs9732 chr4:10076658 T/C cg26043149 chr18:55253948 FECH 1.13 11.36 0.71 6.22e-21 Gout;Urate levels;Serum uric acid levels; TGCT cis rs35306767 0.903 rs4522091 chr10:874116 G/T cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs56036086 1.000 rs73187245 chr22:50625449 C/T cg01548456 chr22:50352384 NA 0.36 5.17 0.42 9.29e-7 Platelet count;Plateletcrit; TGCT cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg13699009 chr12:122356056 WDR66 0.32 7.33 0.55 2.6e-11 Mean corpuscular volume; TGCT cis rs6546537 0.571 rs4852274 chr2:69780637 G/A cg10773587 chr2:69614142 GFPT1 -0.76 -6.86 -0.52 2.87e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs459571 0.916 rs109536 chr9:136889987 G/C cg14405625 chr9:136855902 VAV2 -0.3 -4.48 -0.37 1.67e-5 Platelet distribution width; TGCT cis rs12989701 1.000 rs6710467 chr2:127889932 C/T cg02161262 chr2:127865248 BIN1 0.68 4.51 0.38 1.5e-5 Alzheimer's disease (late onset); TGCT cis rs12048904 1.000 rs12048904 chr1:101331536 C/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.47 -4.45 -0.37 1.91e-5 Multiple sclerosis; TGCT cis rs12477438 0.508 rs2516832 chr2:99771268 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs12142240 0.698 rs67200518 chr1:46835777 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs3947 0.951 rs1736086 chr8:11704897 C/T cg02840367 chr8:11660030 FDFT1 0.91 6.83 0.52 3.37e-10 Blood protein levels; TGCT cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.59 5.97 0.47 2.31e-8 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.623 rs11651858 chr17:29170718 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11711311 0.955 rs34048496 chr3:113414121 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.77 -6.83 -0.52 3.42e-10 IgG glycosylation; TGCT cis rs12188164 0.930 rs11743825 chr5:475463 C/T cg22025206 chr5:502436 SLC9A3 -0.25 -4.44 -0.37 1.97e-5 Cystic fibrosis severity; TGCT cis rs11690935 0.851 rs10201430 chr2:172813241 T/C cg13550731 chr2:172543902 DYNC1I2 -0.81 -7.08 -0.54 9.26e-11 Schizophrenia; TGCT cis rs1887596 0.705 rs533287 chr13:27197419 G/A cg01312412 chr13:27282625 NA 0.3 5.38 0.44 3.56e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs1218582 0.772 rs11264282 chr1:154867370 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.94 -0.53 1.94e-10 Prostate cancer; TGCT cis rs6815814 0.678 rs9715841 chr4:38774503 T/C cg02016764 chr4:38805732 TLR1 -0.28 -4.79 -0.4 4.63e-6 Breast cancer; TGCT cis rs17539620 0.534 rs76931320 chr6:154833508 G/A cg20019720 chr6:154832845 CNKSR3 0.57 4.77 0.39 5.03e-6 Lipoprotein (a) levels; TGCT cis rs73198271 0.960 rs73198287 chr8:8612786 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.65 -0.39 8.24e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9913156 0.639 rs72824971 chr17:4604270 A/G cg23387401 chr17:4582204 PELP1 0.31 4.61 0.38 9.84e-6 Lymphocyte counts; TGCT cis rs9486715 0.867 rs9384602 chr6:96919561 G/A cg06623918 chr6:96969491 KIAA0776 1.1 15.31 0.81 2.34e-30 Headache; TGCT trans rs1814175 0.754 rs28593359 chr11:50042357 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg08280861 chr8:58055591 NA 0.36 4.91 0.4 2.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs2439831 0.850 rs12442297 chr15:44168470 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.74 4.66 0.39 7.89e-6 Lung cancer in ever smokers; TGCT cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg11502198 chr6:26597334 ABT1 0.55 4.88 0.4 3.2e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg16325326 chr1:53192061 ZYG11B 0.59 7.1 0.54 8.48e-11 Monocyte count; TGCT trans rs7613875 0.620 rs17657688 chr3:50033228 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs2486288 0.656 rs10519018 chr15:45549265 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.39e-7 Glomerular filtration rate; TGCT cis rs1903068 0.657 rs2239702 chr4:55992139 C/T cg01777861 chr4:56023843 NA 0.51 5.49 0.44 2.13e-7 Endometriosis; TGCT cis rs12421382 0.881 rs1808843 chr11:109389471 A/G cg16359550 chr11:109292809 C11orf87 0.53 5.87 0.47 3.69e-8 Schizophrenia; TGCT cis rs763014 0.865 rs2018789 chr16:632051 T/C cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs67311347 1.000 rs9848083 chr3:40466979 A/G cg13683864 chr3:40499215 RPL14 1.04 10.79 0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9894429 0.690 rs11869779 chr17:79570067 C/T cg21984481 chr17:79567631 NPLOC4 0.26 4.9 0.4 2.91e-6 Eye color traits; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg01802117 chr1:53393560 SCP2 -0.41 -4.8 -0.4 4.39e-6 Monocyte count; TGCT cis rs1371867 0.875 rs1371868 chr8:101330267 C/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs2458413 0.935 rs2514667 chr8:105358590 C/T cg23108931 chr8:105342351 NA 0.4 7.02 0.53 1.27e-10 Paget's disease; TGCT cis rs8077889 1.000 rs17742905 chr17:41891143 C/A cg26893861 chr17:41843967 DUSP3 1.07 12.6 0.75 5.99e-24 Triglycerides; TGCT cis rs707040 1.000 rs6726767 chr2:155237339 A/T cg18104148 chr2:154337490 NA 0.19 4.56 0.38 1.2e-5 Sudden cardiac arrest; TGCT cis rs7666738 0.753 rs11097594 chr4:98944486 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.737 rs7584314 chr2:238361089 C/T cg14458575 chr2:238380390 NA 0.51 8.09 0.59 4.69e-13 Prostate cancer; TGCT cis rs6570726 0.791 rs12208019 chr6:145935572 T/C cg13319975 chr6:146136371 FBXO30 -0.53 -4.75 -0.39 5.62e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg11644478 chr21:40555479 PSMG1 -0.55 -5.17 -0.42 9.24e-7 Menarche (age at onset); TGCT cis rs367943 1.000 rs348957 chr5:112821178 C/T cg12552261 chr5:112820674 MCC 0.24 4.91 0.4 2.81e-6 Type 2 diabetes; TGCT cis rs2033711 0.728 rs4801586 chr19:58934528 A/G cg04608855 chr19:58913158 NA 0.57 5.7 0.46 8.44e-8 Uric acid clearance; TGCT cis rs2235642 0.893 rs8051295 chr16:1588087 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.56 -0.45 1.61e-7 Coronary artery disease; TGCT cis rs12762955 0.561 rs7918118 chr10:1042823 C/A cg26597838 chr10:835615 NA -0.46 -6.1 -0.48 1.23e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs17266357 0.625 rs75088535 chr4:102725320 A/C cg14855874 chr4:102712397 BANK1 0.41 4.86 0.4 3.47e-6 Blood protein levels; TGCT cis rs6671200 1.000 rs35143903 chr1:95622527 C/T cg03123541 chr1:95699097 RWDD3 0.85 5.93 0.47 2.86e-8 Stearic acid (18:0) levels; TGCT cis rs2153535 0.601 rs4140584 chr6:8540614 C/G cg23788917 chr6:8435910 SLC35B3 -0.62 -5.57 -0.45 1.49e-7 Motion sickness; TGCT cis rs17270561 0.541 rs12192932 chr6:25911502 A/G cg16482183 chr6:26056742 HIST1H1C 0.94 7.33 0.55 2.58e-11 Iron status biomarkers; TGCT cis rs950169 0.509 rs71395455 chr15:85153804 A/G cg12863693 chr15:85201151 NMB 0.41 4.88 0.4 3.26e-6 Schizophrenia; TGCT cis rs904251 0.772 rs10692 chr6:37450914 T/C cg08126542 chr6:37504118 NA -0.39 -4.58 -0.38 1.1e-5 Cognitive performance; TGCT cis rs9926296 0.605 rs1800287 chr16:89858525 C/G cg27121462 chr16:89883253 FANCA 0.81 9.17 0.64 1.26e-15 Vitiligo; TGCT cis rs6714710 0.603 rs35505530 chr2:98506910 T/C cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2956278 0.717 rs7136513 chr12:84674445 T/C cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg03517284 chr6:25882590 NA 0.78 8.11 0.59 4.26e-13 Blood metabolite levels; TGCT cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg05665937 chr4:1216051 CTBP1 0.23 4.48 0.37 1.69e-5 Obesity-related traits; TGCT cis rs9916302 0.706 rs9908131 chr17:37520449 T/C cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs6933660 0.745 rs6557138 chr6:151732017 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.65 6.34 0.49 3.82e-9 Menarche (age at onset); TGCT cis rs7572733 0.534 rs11890137 chr2:198816662 G/A cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs7727544 0.716 rs7701414 chr5:131585958 A/G cg24060327 chr5:131705240 SLC22A5 -0.56 -5.45 -0.44 2.58e-7 Blood metabolite levels; TGCT cis rs5769765 0.955 rs1321 chr22:50297435 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs7975161 0.506 rs7953434 chr12:104622101 T/G cg25273343 chr12:104657179 TXNRD1 -0.42 -5.8 -0.46 5.29e-8 Toenail selenium levels; TGCT cis rs447921 0.736 rs28715905 chr17:74448063 A/C cg09812376 chr17:74270190 QRICH2 0.45 4.76 0.39 5.3e-6 Mitochondrial DNA levels; TGCT cis rs9341808 0.754 rs10806185 chr6:80954511 G/A cg08355045 chr6:80787529 NA 0.29 5.1 0.42 1.23e-6 Sitting height ratio; TGCT cis rs36051895 0.664 rs12340866 chr9:5094185 G/A cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs4746818 1.000 rs7893492 chr10:70960448 C/T cg11621586 chr10:70884670 VPS26A -1.1 -7.75 -0.57 2.8e-12 Left atrial antero-posterior diameter; TGCT cis rs7208859 0.673 rs73263785 chr17:29214808 C/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3796352 1.000 rs71299622 chr3:52917038 G/A cg15956490 chr3:53032818 SFMBT1 0.56 4.94 0.41 2.52e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs739496 0.843 rs625093 chr12:111988432 A/G cg10833066 chr12:111807467 FAM109A 0.37 4.96 0.41 2.31e-6 Platelet count; TGCT cis rs896322 0.843 rs1172155 chr1:205220241 T/C cg03975844 chr1:205318888 KLHDC8A -0.24 -4.5 -0.37 1.52e-5 Mean platelet volume; TGCT cis rs6582630 0.555 rs1906260 chr12:38601013 T/G cg13010199 chr12:38710504 ALG10B 0.65 5.15 0.42 9.92e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs12220238 0.722 rs10509350 chr10:76383071 A/C cg19889307 chr10:75911429 ADK;AP3M1 -0.64 -5.11 -0.42 1.17e-6 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7043114 0.525 rs1133908 chr9:95068046 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.57 -0.45 1.53e-7 Height; TGCT cis rs7178572 1.000 rs7178572 chr15:77747190 A/G cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg06221963 chr1:154839813 KCNN3 -0.76 -13.06 -0.76 4.81e-25 Prostate cancer; TGCT cis rs9985766 0.958 rs10031412 chr4:151005755 G/A cg05926478 chr4:151174724 DCLK2 -0.24 -4.72 -0.39 6.32e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs7100689 0.577 rs10749550 chr10:82031197 A/G cg01528321 chr10:82214614 TSPAN14 0.69 6.61 0.51 1.02e-9 Post bronchodilator FEV1; TGCT cis rs9549367 0.737 rs11619691 chr13:113904636 T/C cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs7605378 1.000 rs2346662 chr2:200679158 C/T cg23649088 chr2:200775458 C2orf69 0.32 5.6 0.45 1.31e-7 Osteoporosis; TGCT cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg06481639 chr22:41940642 POLR3H -0.71 -6.02 -0.48 1.79e-8 Vitiligo; TGCT cis rs6088580 0.634 rs6119497 chr20:33012529 T/A cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs950169 0.922 rs4842939 chr15:84827966 C/T cg17173187 chr15:85201210 NMB -0.51 -5.34 -0.43 4.26e-7 Schizophrenia; TGCT cis rs76419734 0.614 rs17035951 chr4:106527613 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.81 4.63 0.38 9.19e-6 Post bronchodilator FEV1; TGCT cis rs62064224 0.553 rs9896320 chr17:30689814 G/A cg18200150 chr17:30822561 MYO1D 0.41 4.91 0.4 2.81e-6 Schizophrenia; TGCT cis rs1218582 0.741 rs10908446 chr1:154869559 G/A cg06221963 chr1:154839813 KCNN3 -0.76 -12.68 -0.75 3.85e-24 Prostate cancer; TGCT cis rs1997103 1.000 rs2140915 chr7:55410699 G/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4319547 0.661 rs10846830 chr12:122897220 C/G cg08088222 chr12:122070432 ORAI1 0.25 4.43 0.37 2.01e-5 Body mass index; TGCT cis rs9534288 0.913 rs9534299 chr13:46625586 A/T cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs6460942 1.000 rs73053531 chr7:12317474 T/C cg06484146 chr7:12443880 VWDE -0.55 -4.56 -0.38 1.22e-5 Coronary artery disease; TGCT cis rs807669 0.777 rs9605972 chr22:19253274 C/T cg02655711 chr22:19163373 SLC25A1 0.34 7.65 0.57 4.96e-12 Metabolite levels; TGCT cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg08859206 chr1:53392774 SCP2 0.35 5.04 0.41 1.62e-6 Monocyte count; TGCT cis rs6840360 1.000 rs1366909 chr4:152588421 A/C cg17479576 chr4:152424074 FAM160A1 -0.46 -4.9 -0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT trans rs2727020 0.513 rs10839307 chr11:49609843 A/C cg03929089 chr4:120376271 NA -0.74 -9.0 -0.63 3.22e-15 Coronary artery disease; TGCT cis rs1799949 0.929 rs4792988 chr17:41437547 T/C cg23758822 chr17:41437982 NA 0.68 6.37 0.5 3.42e-9 Menopause (age at onset); TGCT cis rs9814567 0.963 rs36006513 chr3:134291913 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3087591 1.000 rs7406983 chr17:29703374 G/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.52 -0.56 9.58e-12 Hip circumference; TGCT cis rs854765 0.647 rs7212447 chr17:17987067 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.68 7.01 0.53 1.33e-10 Total body bone mineral density; TGCT trans rs1973993 0.544 rs2800427 chr1:97002766 A/C cg10631902 chr5:14652156 NA 0.37 9.46 0.65 2.54e-16 Weight; TGCT cis rs3733585 0.638 rs28715627 chr4:9958140 T/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.71e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs1334894 1.000 rs72913423 chr6:35575707 A/G cg24281267 chr6:35479648 TULP1 -0.43 -4.5 -0.37 1.56e-5 Coronary artery disease; TGCT cis rs6088580 0.634 rs6059867 chr20:33078103 C/T cg08999081 chr20:33150536 PIGU 0.29 5.95 0.47 2.56e-8 Glomerular filtration rate (creatinine); TGCT cis rs10464366 0.544 rs9639812 chr7:39192058 C/T cg18850127 chr7:39170497 POU6F2 0.32 6.96 0.53 1.78e-10 IgG glycosylation; TGCT cis rs9467773 1.000 rs6933176 chr6:26540178 G/A cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.593 rs2309811 chr2:100862359 A/G cg07810366 chr2:100720526 AFF3 -0.4 -6.33 -0.49 4.07e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs877282 1.000 rs11253361 chr10:770387 T/C cg22713356 chr15:30763199 NA 1.26 10.48 0.69 8.73e-19 Uric acid levels; TGCT cis rs10927875 0.722 rs1763605 chr1:16338925 T/G cg21385522 chr1:16154831 NA 0.6 6.38 0.5 3.14e-9 Dilated cardiomyopathy; TGCT cis rs344364 0.511 rs1742473 chr16:1953095 T/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.46 -5.31 -0.43 4.97e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9517313 0.592 rs11069311 chr13:99202101 G/T cg07423050 chr13:99094983 FARP1 -0.27 -5.42 -0.44 2.92e-7 Neuroticism; TGCT trans rs12339966 0.653 rs4237128 chr9:11289842 C/T cg07173112 chr1:1114698 TTLL10 -0.34 -6.88 -0.53 2.65e-10 Systolic blood pressure; TGCT cis rs3733585 0.638 rs28715627 chr4:9958140 T/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.68 -0.51 7.16e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9467711 0.932 rs11966360 chr6:26316982 A/G cg02458000 chr6:26745757 NA -0.92 -5.21 -0.42 7.52e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2535633 0.631 rs2465101 chr3:52991307 A/T cg05573699 chr3:52720067 GNL3;PBRM1 0.57 5.41 0.44 3.06e-7 Body mass index; TGCT cis rs7565124 0.909 rs6747472 chr2:20252007 C/T cg00462460 chr2:20212509 MATN3 -0.44 -4.66 -0.39 8.07e-6 Major depressive disorder; TGCT cis rs6089829 0.962 rs6122347 chr20:61661866 C/T cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg18867708 chr6:26865862 GUSBL1 -0.38 -5.03 -0.41 1.65e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1729951 0.546 rs835634 chr3:136676303 C/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs7980687 0.657 rs2851447 chr12:123665113 G/C cg00376283 chr12:123451042 ABCB9 0.78 6.64 0.51 8.94e-10 Height;Educational attainment;Head circumference (infant); TGCT cis rs2832191 0.720 rs7277028 chr21:30494604 T/C cg08807101 chr21:30365312 RNF160 -0.62 -5.74 -0.46 6.74e-8 Dental caries; TGCT cis rs6088590 0.931 rs12625149 chr20:33425812 A/C cg06115741 chr20:33292138 TP53INP2 -0.64 -5.17 -0.42 9.29e-7 Coronary artery disease; TGCT cis rs1008375 0.932 rs4235390 chr4:17696378 G/T cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs7659604 0.521 rs4833234 chr4:122694799 T/C cg19748678 chr4:122722346 EXOSC9 -0.57 -5.67 -0.45 9.35e-8 Type 2 diabetes; TGCT cis rs6831352 0.918 rs17218108 chr4:100055755 T/C cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs11690935 0.571 rs1008151 chr2:172912098 G/A cg13550731 chr2:172543902 DYNC1I2 0.64 5.83 0.46 4.45e-8 Schizophrenia; TGCT cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.25 0.49 6.02e-9 Schizophrenia; TGCT cis rs7267979 1.000 rs6076339 chr20:25348712 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2576037 0.583 rs2576050 chr18:44558912 T/C cg23302884 chr18:44338147 ST8SIA5 0.4 4.79 0.4 4.67e-6 Personality dimensions; TGCT cis rs1577917 0.687 rs1470531 chr6:86507369 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs8062405 0.824 rs62034326 chr16:28539293 A/G cg09754948 chr16:28834200 ATXN2L 0.58 4.57 0.38 1.14e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs11098499 0.954 rs3733519 chr4:120423448 A/G cg09307838 chr4:120376055 NA 0.67 6.3 0.49 4.63e-9 Corneal astigmatism; TGCT cis rs2204008 0.702 rs8175764 chr12:38363690 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.44e-11 Bladder cancer; TGCT cis rs6967414 0.605 rs7786706 chr7:6747267 C/T cg09896999 chr7:6746977 ZNF12 -0.43 -5.28 -0.43 5.51e-7 Hematocrit;Hemoglobin concentration; TGCT cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs290268 0.838 rs290989 chr9:93561836 T/C cg02608019 chr9:93564028 SYK 0.44 4.44 0.37 1.94e-5 Platelet count; TGCT cis rs885389 0.920 rs1880842 chr12:131621997 A/G cg07124762 chr12:131619285 GPR133 -0.29 -5.21 -0.42 7.65e-7 RR interval (heart rate); TGCT cis rs7267979 0.714 rs6115107 chr20:25237390 A/G cg03522245 chr20:25566470 NINL 0.48 4.59 0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3617 0.539 rs9825369 chr3:52953311 T/C cg11645453 chr3:52864694 ITIH4 -0.27 -5.39 -0.44 3.38e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.754 rs4896838 chr6:146015451 T/C cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs7223966 1.000 rs17549954 chr17:61707032 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.76 0.39 5.39e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg22442454 chr1:209979470 IRF6 0.62 4.53 0.38 1.35e-5 Cleft lip with or without cleft palate; TGCT cis rs4285028 0.948 rs2332033 chr3:121699548 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs9517320 0.515 rs9556972 chr13:99209815 C/T cg07423050 chr13:99094983 FARP1 -0.22 -4.46 -0.37 1.79e-5 Longevity; TGCT cis rs7940866 0.838 rs1991898 chr11:130801786 C/G cg12179176 chr11:130786555 SNX19 -0.64 -6.42 -0.5 2.66e-9 Schizophrenia; TGCT cis rs7226408 0.857 rs72887024 chr18:34468482 G/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs926938 0.527 rs360666 chr1:115481290 C/T cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs1497406 0.590 rs3818162 chr1:16528600 G/A cg20430773 chr1:16534157 ARHGEF19 0.49 5.61 0.45 1.25e-7 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg11494091 chr17:61959527 GH2 -0.58 -14.95 -0.8 1.58e-29 Prudent dietary pattern; TGCT cis rs3796352 1.000 rs71301809 chr3:53090312 C/T cg07884673 chr3:53033167 SFMBT1 0.61 6.25 0.49 6e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs12142240 0.667 rs55887761 chr1:46826587 C/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs8083786 1 rs8083786 chr18:12881361 A/G cg23598886 chr18:12777645 NA -0.55 -4.86 -0.4 3.43e-6 Rheumatoid arthritis; TGCT cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs2276314 0.947 rs4799831 chr18:33554775 A/G cg05985134 chr18:33552581 C18orf21 0.54 4.82 0.4 4.12e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs10875746 0.859 rs12305511 chr12:48582716 C/T cg20731937 chr12:48336164 NA -0.59 -4.72 -0.39 6.13e-6 Longevity (90 years and older); TGCT cis rs11105298 0.891 rs10858902 chr12:89927789 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.12 -0.42 1.12e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs769267 0.965 rs735273 chr19:19385411 T/C cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs2721195 0.626 rs59464125 chr8:145857786 G/A cg12270520 chr8:146023939 ZNF517 -0.6 -5.25 -0.43 6.29e-7 Age at first birth; TGCT cis rs854765 0.562 rs2955381 chr17:17945500 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg12310025 chr6:25882481 NA 0.54 5.46 0.44 2.44e-7 Blood metabolite levels; TGCT cis rs4919044 0.674 rs11187260 chr10:94809187 A/G cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs13188771 0.690 rs10040426 chr5:100896781 T/C cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs42648 0.935 rs7803012 chr7:90026166 A/T cg25739043 chr7:89950458 NA 0.65 6.24 0.49 6.29e-9 Homocysteine levels; TGCT cis rs7267979 0.789 rs6083810 chr20:25329759 T/A cg21995068 chr20:25989032 LOC100134868 0.43 5.19 0.42 8.41e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4805272 0.626 rs6509072 chr19:29331703 C/G cg04546413 chr19:29218101 NA 0.56 4.47 0.37 1.73e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg05025164 chr4:1340916 KIAA1530 -0.65 -5.45 -0.44 2.63e-7 Longevity; TGCT cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs4961252 0.505 rs4961327 chr8:142102053 C/T cg09914555 chr8:142094789 NA -0.4 -6.0 -0.47 1.99e-8 Isovolumetric relaxation time;Response to interferon beta therapy; TGCT cis rs807669 0.548 rs5748028 chr22:19172281 G/A cg02655711 chr22:19163373 SLC25A1 0.33 6.89 0.53 2.54e-10 Metabolite levels; TGCT cis rs7267979 0.789 rs1983974 chr20:25530619 A/C cg14121845 chr20:25566513 NINL -0.45 -4.69 -0.39 7.14e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4237845 0.804 rs10877034 chr12:58286444 T/C cg02175503 chr12:58329896 NA 0.49 5.01 0.41 1.85e-6 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.512 rs6060941 chr20:30367383 C/T cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs6429082 0.818 rs704714 chr1:235632094 T/C cg26050004 chr1:235667680 B3GALNT2 0.59 5.26 0.43 6.02e-7 Adiposity; TGCT cis rs7726839 0.540 rs3749615 chr5:601485 C/T cg09021430 chr5:549028 NA -0.39 -5.32 -0.43 4.78e-7 Obesity-related traits; TGCT cis rs6087771 0.642 rs6060403 chr20:30221104 C/A cg10886678 chr20:30946050 ASXL1 -0.57 -4.5 -0.37 1.55e-5 Subcortical brain region volumes;Putamen volume; TGCT cis rs3947 0.789 rs8005 chr8:11701096 A/C cg02840367 chr8:11660030 FDFT1 -1.03 -8.54 -0.61 3.97e-14 Blood protein levels; TGCT cis rs7772486 0.875 rs9390371 chr6:146363180 A/G cg23711669 chr6:146136114 FBXO30 0.85 9.44 0.65 2.92e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2479724 0.905 rs2274578 chr6:41888827 C/G cg08135965 chr6:41755394 TOMM6 0.48 4.65 0.39 8.44e-6 Menarche (age at onset); TGCT cis rs28595532 0.920 rs10018977 chr4:119785229 C/T cg14228332 chr4:119757509 SEC24D 1.19 6.66 0.51 8.07e-10 Cannabis dependence symptom count; TGCT cis rs782590 0.818 rs2627765 chr2:55883317 G/T cg18811423 chr2:55921094 PNPT1 0.61 5.83 0.46 4.58e-8 Metabolic syndrome; TGCT cis rs9902453 0.817 rs17226179 chr17:28168573 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.89 0.53 2.51e-10 Coffee consumption (cups per day); TGCT cis rs4803468 1.000 rs10422783 chr19:41906436 T/C cg09537434 chr19:41945824 ATP5SL -0.89 -10.02 -0.67 1.14e-17 Height; TGCT cis rs9467711 0.659 rs36162392 chr6:26569135 T/C cg16898833 chr6:26189333 HIST1H4D 1.26 5.87 0.47 3.76e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs1577917 0.958 rs12215232 chr6:86785430 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -5.0 -0.41 1.95e-6 Response to antipsychotic treatment; TGCT cis rs9677476 0.516 rs10199752 chr2:231969554 A/C cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs10504229 0.815 rs16921955 chr8:58164553 C/T cg21724239 chr8:58056113 NA 0.39 4.91 0.4 2.81e-6 Developmental language disorder (linguistic errors); TGCT cis rs2067615 0.524 rs4964483 chr12:107099057 T/C cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs9443645 0.869 rs1507154 chr6:79503700 C/T cg09184832 chr6:79620586 NA -0.45 -4.78 -0.39 4.96e-6 Intelligence (multi-trait analysis); TGCT cis rs7833790 0.660 rs7839178 chr8:82763479 A/G cg17211192 chr8:82754475 SNX16 0.97 9.09 0.63 2.04e-15 Diastolic blood pressure; TGCT cis rs2013441 1.000 rs2526472 chr17:20137888 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs595982 0.527 rs56021835 chr19:49369989 G/A cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.25 -0.64 8.09e-16 Red cell distribution width; TGCT cis rs72615157 0.612 rs7786505 chr7:99817585 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.6 -4.99 -0.41 1.97e-6 Lung function (FEV1/FVC); TGCT cis rs2070433 0.556 rs8129460 chr21:47822544 C/T cg12379764 chr21:47803548 PCNT 0.55 4.77 0.39 5.07e-6 Lymphocyte counts; TGCT cis rs854765 0.647 rs854818 chr17:18022039 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.51 0.56 1.01e-11 Total body bone mineral density; TGCT cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs427394 0.802 rs274720 chr5:6719933 A/G cg10857441 chr5:6722123 POLS -0.32 -7.8 -0.57 2.17e-12 Menopause (age at onset); TGCT cis rs7089973 0.604 rs11196952 chr10:116607592 G/A cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9899728 0.539 rs56267297 chr17:73046996 T/C cg27626185 chr17:73056755 KCTD2 -0.91 -8.01 -0.58 7.02e-13 Alzheimer's disease or small vessel stroke; TGCT cis rs2997447 0.846 rs72886619 chr1:26452604 G/A cg03844060 chr1:26490628 NA 0.27 4.44 0.37 1.99e-5 QRS complex (12-leadsum); TGCT cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs4820539 0.933 rs2267004 chr22:23459863 G/A cg14186256 chr22:23484241 RTDR1 0.99 11.73 0.73 7.92e-22 Bone mineral density; TGCT trans rs6089829 0.888 rs4809268 chr20:61675249 C/G cg23505145 chr19:12996616 KLF1 0.96 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Vitiligo; TGCT cis rs950169 0.922 rs6603022 chr15:84830170 T/C cg17173187 chr15:85201210 NMB -0.54 -5.52 -0.44 1.94e-7 Schizophrenia; TGCT cis rs9549367 0.789 rs9549699 chr13:113878263 T/A cg00898013 chr13:113819073 PROZ -0.39 -4.78 -0.39 4.78e-6 Platelet distribution width; TGCT cis rs950880 0.560 rs10191914 chr2:102930657 T/C cg09003973 chr2:102972529 NA -0.51 -4.49 -0.37 1.59e-5 Serum protein levels (sST2); TGCT cis rs7822232 0.908 rs7821112 chr8:145147169 G/A cg06495924 chr8:145149574 CYC1 1.04 4.49 0.37 1.6e-5 Blood metabolite levels; TGCT cis rs2842992 0.915 rs2842980 chr6:160100116 A/T cg11366901 chr6:160182831 ACAT2 0.83 5.33 0.43 4.48e-7 Age-related macular degeneration (geographic atrophy); TGCT cis rs4332037 0.539 rs34809719 chr7:2028968 G/T cg25834613 chr7:1915315 MAD1L1 -0.47 -4.51 -0.38 1.48e-5 Bipolar disorder; TGCT cis rs8072100 0.581 rs4267364 chr17:45781264 A/G cg08085267 chr17:45401833 C17orf57 -0.43 -4.85 -0.4 3.6e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs8014204 0.816 rs4903262 chr14:75340818 A/G cg06637938 chr14:75390232 RPS6KL1 0.54 4.68 0.39 7.5e-6 Caffeine consumption; TGCT cis rs1215050 0.818 rs165238 chr4:98712138 G/T cg05340658 chr4:99064831 C4orf37 0.44 5.63 0.45 1.15e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13108904 0.645 rs56115381 chr4:1324994 G/C cg00684032 chr4:1343700 KIAA1530 0.23 4.68 0.39 7.3e-6 Obesity-related traits; TGCT cis rs151997 0.508 rs9292165 chr5:50272619 T/C cg06027927 chr5:50259733 NA 0.54 5.44 0.44 2.76e-7 Callous-unemotional behaviour; TGCT cis rs950776 0.518 rs12916483 chr15:78832397 G/A cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs2404602 1.000 rs6495206 chr15:76870963 C/T cg22467129 chr15:76604101 ETFA -0.44 -4.94 -0.41 2.5e-6 Blood metabolite levels; TGCT cis rs2228479 0.717 rs34027607 chr16:89808939 T/C cg26513180 chr16:89883248 FANCA 0.78 4.54 0.38 1.32e-5 Skin colour saturation; TGCT cis rs877282 0.842 rs35872126 chr10:764545 G/A cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs79057730 0.599 rs79272827 chr7:807015 C/G cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.29 0.43 5.3e-7 Initial pursuit acceleration; TGCT cis rs35264875 1.000 rs72928652 chr11:68851547 G/A cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs4803468 1.000 rs284648 chr19:41926790 T/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.57 -0.69 5.19e-19 Height; TGCT cis rs9372498 0.536 rs62422224 chr6:118941116 G/A cg21191810 chr6:118973309 C6orf204 -0.38 -4.98 -0.41 2.04e-6 Diastolic blood pressure; TGCT cis rs1552244 0.816 rs13059144 chr3:10010197 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs7043114 0.525 rs6479417 chr9:95064562 G/C cg14631576 chr9:95140430 CENPP -0.28 -4.65 -0.39 8.23e-6 Height; TGCT cis rs7249142 0.549 rs12609573 chr19:19297567 C/T cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B -0.54 -5.36 -0.43 3.9e-7 IgG glycosylation; TGCT cis rs858239 0.601 rs929508 chr7:23166709 C/A cg05602783 chr7:23145260 KLHL7 -0.65 -5.48 -0.44 2.32e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs950169 0.840 rs72748702 chr15:84915246 A/G cg11189052 chr15:85197271 WDR73 0.83 6.67 0.51 7.71e-10 Schizophrenia; TGCT cis rs2549003 0.966 rs2706386 chr5:131832687 C/T cg02551604 chr5:131831745 NA 0.93 12.59 0.75 6.56e-24 Asthma (sex interaction); TGCT cis rs453301 0.686 rs28665409 chr8:8869277 G/A cg00184457 chr8:8946301 NA -0.26 -4.71 -0.39 6.41e-6 Joint mobility (Beighton score); TGCT cis rs16957091 0.647 rs4924705 chr15:43380260 C/T cg17935677 chr15:44119062 WDR76 0.55 4.78 0.39 4.95e-6 MGMT methylation in smokers; TGCT cis rs308447 0.516 rs6815982 chr4:123677472 C/T cg10495464 chr4:123653540 BBS12;LOC729338 -0.65 -6.46 -0.5 2.12e-9 Perceived unattractiveness to mosquitoes; TGCT cis rs3099143 1.000 rs2011635 chr15:77134891 T/A cg21673338 chr15:77095150 SCAPER -0.52 -5.0 -0.41 1.94e-6 Recalcitrant atopic dermatitis; TGCT cis rs6088590 0.542 rs6059956 chr20:33220070 A/G cg06115741 chr20:33292138 TP53INP2 0.56 5.04 0.41 1.59e-6 Coronary artery disease; TGCT cis rs78366141 0.649 rs112818517 chr4:89653103 G/A cg01026744 chr4:89619053 NAP1L5;HERC3 1.16 5.16 0.42 9.33e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs2692947 0.599 rs7561198 chr2:96774981 C/G cg22654517 chr2:96458247 NA -0.21 -4.58 -0.38 1.11e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7752195 0.558 rs74548903 chr6:25245898 C/T cg16898833 chr6:26189333 HIST1H4D 1.17 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.520 rs11123763 chr2:99750673 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs250677 0.522 rs10040798 chr5:148367324 A/G cg18129178 chr5:148520854 ABLIM3 0.36 4.73 0.39 5.97e-6 Breast cancer; TGCT cis rs72720396 1.000 rs72720396 chr1:91191582 A/G cg13456504 chr1:91191583 NA 0.74 5.83 0.46 4.57e-8 Morning vs. evening chronotype;Chronotype; TGCT cis rs6901004 0.596 rs411604 chr6:111565847 A/G cg15721981 chr6:111408429 SLC16A10 -0.61 -5.02 -0.41 1.78e-6 Blood metabolite levels; TGCT cis rs765787 0.530 rs1706764 chr15:45524256 T/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg13695892 chr22:41940480 POLR3H -0.87 -8.08 -0.59 4.83e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs66573146 1.000 rs6838250 chr4:6973184 C/G cg05069807 chr4:6945702 TBC1D14 0.35 4.94 0.41 2.51e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7937612 0.965 rs7932037 chr11:120259430 T/A cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.5 -0.37 1.53e-5 Intraocular pressure; TGCT cis rs7666738 0.606 rs4637413 chr4:99088151 A/G cg05340658 chr4:99064831 C4orf37 0.44 4.8 0.4 4.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg26818010 chr10:134567672 INPP5A -0.38 -5.37 -0.43 3.66e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11792861 0.816 rs3818932 chr9:111664178 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 5.01 0.41 1.85e-6 Menarche (age at onset); TGCT cis rs826838 0.967 rs11183514 chr12:38760744 A/T cg26384229 chr12:38710491 ALG10B 1.08 10.86 0.7 1.01e-19 Heart rate; TGCT cis rs2658782 0.724 rs2248655 chr11:93254612 T/C cg15737290 chr11:93063684 CCDC67 0.6 4.6 0.38 1.01e-5 Pulmonary function decline; TGCT cis rs6688613 0.694 rs12062326 chr1:166820186 G/A cg07049167 chr1:166818506 POGK 0.24 5.15 0.42 9.86e-7 Refractive astigmatism; TGCT cis rs9430161 0.579 rs7542158 chr1:11040193 G/A cg02454025 chr1:11042201 C1orf127 0.97 12.71 0.75 3.27e-24 Ewing sarcoma; TGCT cis rs12519773 0.550 rs4242242 chr5:92519387 G/A cg04854328 chr5:92914828 FLJ42709 -0.3 -4.54 -0.38 1.29e-5 Migraine; TGCT cis rs144345632 1 rs144345632 chr6:96886894 T/TA cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs265548 0.510 rs28415068 chr19:17910582 T/A cg04517722 chr19:17905589 B3GNT3 0.4 5.22 0.42 7.22e-7 Tumor biomarkers; TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs4466137 0.951 rs336958 chr5:82973396 A/G cg16102102 chr5:83017553 HAPLN1 -0.91 -9.61 -0.65 1.12e-16 Prostate cancer; TGCT cis rs12220238 1.000 rs2395077 chr10:75932001 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg09222892 chr1:25734099 RHCE -0.43 -7.1 -0.54 8.62e-11 Erythrocyte sedimentation rate; TGCT cis rs1008375 0.868 rs6816286 chr4:17698088 A/G cg18681998 chr4:17616180 MED28 0.8 7.36 0.55 2.24e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12510870 0.599 rs1247668 chr4:74446796 A/G cg05868023 chr4:75230803 EREG 0.53 4.67 0.39 7.77e-6 Iris color (b* coordinate); TGCT cis rs3784262 0.709 rs4080 chr15:58201341 C/G cg12031962 chr15:58353849 ALDH1A2 0.51 7.26 0.55 3.66e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2463822 0.688 rs7121684 chr11:62162389 T/C cg06239285 chr11:62104954 ASRGL1 -0.85 -5.54 -0.45 1.76e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg08219700 chr8:58056026 NA 0.3 4.57 0.38 1.14e-5 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg11644478 chr21:40555479 PSMG1 -0.56 -5.01 -0.41 1.8e-6 Cognitive function; TGCT cis rs2832191 0.791 rs2065270 chr21:30485420 T/C cg08807101 chr21:30365312 RNF160 -0.66 -6.19 -0.49 8.15e-9 Dental caries; TGCT cis rs9393777 0.546 rs35589403 chr6:27219491 C/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.53 -4.44 -0.37 1.97e-5 Intelligence (multi-trait analysis); TGCT cis rs6969780 0.841 rs10246712 chr7:27198860 C/T cg04317399 chr7:27170313 HOXA4 0.45 4.56 0.38 1.2e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs12791968 1.000 rs1005935 chr11:45002498 A/C cg11846598 chr11:44996168 LOC221122 -0.36 -6.79 -0.52 4.04e-10 Inhibitory control; TGCT cis rs6490294 0.539 rs2238151 chr12:112211833 T/C cg10833066 chr12:111807467 FAM109A 0.32 5.24 0.43 6.57e-7 Mean platelet volume; TGCT cis rs7267979 0.932 rs6115200 chr20:25487377 G/T cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs12339966 0.581 rs73642443 chr9:11335388 A/G cg03488587 chr11:64876988 C11orf2 0.31 6.88 0.53 2.67e-10 Systolic blood pressure; TGCT cis rs12479064 0.694 rs4341989 chr2:100046783 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.59 -4.74 -0.39 5.67e-6 Chronic sinus infection; TGCT cis rs3780378 1.000 rs10117591 chr9:5094539 G/A cg03508284 chr9:4985524 JAK2 -0.49 -4.61 -0.38 9.8200000000000008e-06 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg04389838 chr3:44770851 ZNF501 -0.4 -5.27 -0.43 5.85e-7 Depressive symptoms; TGCT cis rs7772486 0.875 rs9403764 chr6:146360582 G/A cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2832191 0.791 rs2832199 chr21:30498501 G/A cg08807101 chr21:30365312 RNF160 -0.65 -6.08 -0.48 1.35e-8 Dental caries; TGCT cis rs11122272 0.735 rs2739518 chr1:231537633 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT cis rs11249608 0.548 rs6601007 chr5:178455796 G/C cg21905437 chr5:178450457 ZNF879 0.44 4.57 0.38 1.16e-5 Pubertal anthropometrics; TGCT cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg11890956 chr21:40555474 PSMG1 1.04 10.78 0.7 1.56e-19 Cognitive function; TGCT cis rs2361710 0.611 rs3816257 chr17:78074446 G/T cg22161269 chr17:78836513 RPTOR 0.23 4.54 0.38 1.29e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs12908161 1.000 rs12908549 chr15:85322351 C/G cg17173187 chr15:85201210 NMB 0.57 6.4 0.5 2.89e-9 Schizophrenia; TGCT cis rs10782582 0.569 rs74090722 chr1:76197262 A/G cg22875332 chr1:76189707 ACADM -0.49 -5.33 -0.43 4.44e-7 Daytime sleep phenotypes; TGCT cis rs6964587 1.000 rs6951972 chr7:91689446 T/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs1008375 0.932 rs9283698 chr4:17662471 T/C cg16339924 chr4:17578868 LAP3 0.63 5.22 0.42 7.29e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11674184 0.632 rs17529680 chr2:11727087 A/C cg07314298 chr2:11723111 GREB1 0.38 6.76 0.52 4.79e-10 Endometriosis; TGCT cis rs12780845 0.505 rs11254419 chr10:17209192 A/C cg01003015 chr10:17271136 VIM -0.63 -5.39 -0.44 3.42e-7 Homocysteine levels; TGCT cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg18252515 chr7:66147081 NA -1.13 -6.09 -0.48 1.29e-8 Diabetic kidney disease; TGCT cis rs6988636 1.000 rs16898095 chr8:124193523 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs734999 0.545 rs28532547 chr1:2561286 T/G cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs9987353 0.522 rs2929466 chr8:9063899 G/T cg15556689 chr8:8085844 FLJ10661 -0.55 -5.36 -0.43 3.97e-7 Recombination measurement; TGCT cis rs7107174 1.000 rs10899456 chr11:78000155 C/G cg12700464 chr11:78128424 GAB2 -0.64 -4.51 -0.38 1.46e-5 Testicular germ cell tumor; TGCT cis rs1670533 1.000 rs6857085 chr4:1095920 C/A cg27284194 chr4:1044797 NA -0.7 -6.06 -0.48 1.53e-8 Recombination rate (females); TGCT cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.82 0.7 1.27e-19 Colorectal cancer; TGCT cis rs6690583 0.623 rs61770879 chr1:85504938 A/C cg20280350 chr1:85513789 MCOLN3 -0.71 -4.53 -0.38 1.38e-5 Serum sulfate level; TGCT cis rs939658 0.805 rs8036435 chr15:79420031 T/C cg17916960 chr15:79447300 NA -0.5 -7.7 -0.57 3.74e-12 Refractive error; TGCT cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.47 4.6 0.38 1.04e-5 Prudent dietary pattern; TGCT cis rs7666738 0.962 rs2865950 chr4:99040061 T/C cg17366294 chr4:99064904 C4orf37 0.71 6.53 0.51 1.55e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs1580019 0.547 rs56981934 chr7:32535202 C/G cg07520158 chr7:32535189 LSM5;AVL9 0.59 5.02 0.41 1.72e-6 Cognitive ability; TGCT cis rs7267979 0.844 rs4815413 chr20:25359229 G/T cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7617773 1.000 rs6442106 chr3:48190815 G/A cg11946769 chr3:48343235 NME6 -0.62 -5.59 -0.45 1.37e-7 Coronary artery disease; TGCT cis rs2050392 1.000 rs2183176 chr10:30698544 C/T cg18806716 chr10:30721971 MAP3K8 0.52 6.47 0.5 2.04e-9 Inflammatory bowel disease; TGCT cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg13695892 chr22:41940480 POLR3H -0.81 -8.08 -0.59 4.88e-13 Vitiligo; TGCT cis rs4478037 1.000 rs75576169 chr3:33167801 G/A cg19404215 chr3:33155277 CRTAP 1.26 7.88 0.58 1.43e-12 Major depressive disorder; TGCT cis rs6582630 0.537 rs8189533 chr12:38391068 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.56 0.56 7.83e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs2544527 0.635 rs2693008 chr2:15913019 C/G cg26669897 chr2:15909070 NA -0.44 -5.17 -0.42 8.97e-7 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs763121 0.853 rs5757231 chr22:39071658 C/T cg06022373 chr22:39101656 GTPBP1 -0.77 -7.46 -0.56 1.35e-11 Menopause (age at onset); TGCT cis rs2180341 0.782 rs4487601 chr6:127723521 A/G cg24812749 chr6:127587940 RNF146 0.65 5.19 0.42 8.37e-7 Breast cancer; TGCT cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg11644478 chr21:40555479 PSMG1 1.02 11.05 0.7 3.46e-20 Cognitive function; TGCT cis rs11779988 0.545 rs431961 chr8:17786204 T/G cg01800426 chr8:17659068 MTUS1 -0.7 -5.46 -0.44 2.5e-7 Breast cancer; TGCT cis rs2742234 1.000 rs1864395 chr10:43655697 G/A cg02780029 chr10:43622663 RET -0.26 -5.03 -0.41 1.7e-6 Hirschsprung disease; TGCT cis rs11626933 1.000 rs61986782 chr14:90751344 C/T cg14092571 chr14:90743983 NA -0.3 -6.13 -0.48 1.06e-8 Gut microbiota (bacterial taxa); TGCT cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg15691649 chr6:25882328 NA 0.38 5.06 0.41 1.5e-6 Blood metabolite levels; TGCT cis rs9810089 0.835 rs6791611 chr3:136160590 C/G cg12473912 chr3:136751656 NA -0.35 -5.12 -0.42 1.12e-6 Gestational age at birth (child effect); TGCT cis rs3935685 0.874 rs4886521 chr15:78000321 A/G cg25212270 chr15:78015279 NA 0.26 5.64 0.45 1.08e-7 Intelligence (multi-trait analysis); TGCT cis rs16866061 0.890 rs72972401 chr2:225404668 T/C cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs6461049 0.519 rs3778992 chr7:2175313 C/G cg04267008 chr7:1944627 MAD1L1 -0.4 -5.57 -0.45 1.52e-7 Schizophrenia; TGCT cis rs2075371 0.764 rs1643034 chr7:134006176 A/G cg11752832 chr7:134001865 SLC35B4 0.78 7.42 0.55 1.59e-11 Mean platelet volume; TGCT trans rs3780486 1.000 rs3780486 chr9:33139453 C/T cg04842962 chr6:43655489 MRPS18A 1.15 11.21 0.71 1.47e-20 IgG glycosylation; TGCT cis rs10751667 0.666 rs6597966 chr11:950750 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs950169 0.686 rs12906474 chr15:85109237 A/G cg11189052 chr15:85197271 WDR73 0.79 6.37 0.5 3.37e-9 Schizophrenia; TGCT cis rs2295359 0.824 rs12060309 chr1:67604219 T/C cg08029281 chr1:67600428 NA 0.4 4.54 0.38 1.31e-5 Psoriasis; TGCT cis rs11118844 0.744 rs10863655 chr1:221952515 A/G cg04222084 chr1:221915650 DUSP10 -0.78 -4.66 -0.39 8.03e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs7586879 0.593 rs10198356 chr2:25130592 A/G cg15423357 chr2:25149977 NA 0.52 5.03 0.41 1.65e-6 Body mass index; TGCT cis rs910316 0.967 rs175432 chr14:75615246 C/G cg23033748 chr14:75592666 NEK9 -0.29 -4.78 -0.39 4.86e-6 Height; TGCT cis rs7599312 0.517 rs10192988 chr2:213407782 T/G cg16329650 chr2:213403929 ERBB4 1.07 16.03 0.82 5.29e-32 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9948 0.786 rs62152783 chr2:97457389 T/A cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs2658782 0.789 rs2658775 chr11:93126799 C/T cg18152523 chr11:93063302 CCDC67 -0.58 -4.6 -0.38 1.03e-5 Pulmonary function decline; TGCT cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg02187348 chr16:89574699 SPG7 0.61 6.53 0.51 1.53e-9 Multiple myeloma (IgH translocation); TGCT cis rs782590 0.869 rs782599 chr2:55847423 C/T cg03859395 chr2:55845619 SMEK2 0.9 11.04 0.7 3.81e-20 Metabolic syndrome; TGCT cis rs35306767 0.903 rs35957139 chr10:884889 C/T cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs9896933 0.778 rs80243549 chr17:80821485 G/T cg20578329 chr17:80767326 TBCD -0.35 -4.99 -0.41 1.99e-6 Bone mineral accretion in asthma (oral corticosteroid dose interaction); TGCT cis rs7267979 1.000 rs910997 chr20:25267301 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17384381 1.000 rs17388521 chr1:85897904 A/G cg16011679 chr1:85725395 C1orf52 -0.77 -6.34 -0.49 3.87e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.576 rs7660951 chr4:98651581 T/A cg18180107 chr4:99064573 C4orf37 0.52 4.57 0.38 1.15e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg01585852 chr22:24235823 MIF -0.22 -4.67 -0.39 7.81e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9534288 0.797 rs2104516 chr13:46602123 T/C cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs9814567 1.000 rs9835204 chr3:134261342 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7698623 0.850 rs7676119 chr4:88780778 G/A cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs56399783 0.708 rs55868372 chr7:2758563 G/C cg19731401 chr7:2775893 GNA12 0.36 5.22 0.42 7.45e-7 Childhood ear infection; TGCT cis rs74181299 0.964 rs2723065 chr2:65279414 A/G cg05010058 chr2:65284262 CEP68 0.43 4.87 0.4 3.38e-6 Pulse pressure; TGCT cis rs7926906 1.000 rs4298862 chr11:90523629 C/G cg26138821 chr11:89956704 CHORDC1 -0.53 -5.69 -0.46 8.52e-8 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.659 rs35082010 chr17:56936867 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs9916302 0.595 rs4795371 chr17:37636695 T/G cg15445000 chr17:37608096 MED1 0.31 4.57 0.38 1.17e-5 Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg18230493 chr5:56204884 C5orf35 -0.67 -5.76 -0.46 6.2e-8 Initial pursuit acceleration; TGCT cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg25036284 chr2:26402008 FAM59B -0.61 -4.89 -0.4 3.1e-6 Gut microbiome composition (summer); TGCT cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs9486719 1.000 rs11152968 chr6:96908653 A/G cg18709589 chr6:96969512 KIAA0776 0.68 5.05 0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs7017914 0.934 rs6987313 chr8:71570989 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs78456975 0.739 rs72776248 chr2:1521314 A/G cg01028140 chr2:1542097 TPO -0.36 -4.86 -0.4 3.55e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs13242816 1.000 rs987790 chr7:116134633 T/A cg02799643 chr7:116139180 CAV2 -0.46 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs990171 1.000 rs4851584 chr2:103060313 A/G cg04239558 chr2:103089729 SLC9A4 0.34 4.67 0.39 7.64e-6 Lymphocyte counts; TGCT cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs9393692 0.645 rs766407 chr6:26319534 T/C cg00631329 chr6:26305371 NA -0.46 -6.91 -0.53 2.23e-10 Educational attainment; TGCT trans rs7618501 1.000 rs7648987 chr3:49868455 A/G cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs250677 0.522 rs6580589 chr5:148360335 C/G cg18129178 chr5:148520854 ABLIM3 0.36 4.69 0.39 7.23e-6 Breast cancer; TGCT cis rs1468333 0.724 rs12514307 chr5:137612143 T/C cg27119451 chr5:137514611 BRD8;KIF20A 0.46 4.46 0.37 1.79e-5 Resting heart rate; TGCT cis rs9906944 0.933 rs4794018 chr17:47093398 T/C cg20966754 chr17:47091339 IGF2BP1 -0.44 -4.99 -0.41 2.04e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs9894429 0.604 rs9912071 chr17:79609654 G/A cg21028142 chr17:79581711 NPLOC4 0.28 6.12 0.48 1.13e-8 Eye color traits; TGCT cis rs35306767 0.903 rs11253475 chr10:907262 C/A cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs7312933 0.524 rs11181465 chr12:42765098 T/G cg19980929 chr12:42632907 YAF2 0.43 6.03 0.48 1.79e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs3772130 0.583 rs58088236 chr3:121561765 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.59 5.43 0.44 2.8e-7 Cognitive performance; TGCT cis rs42648 0.869 rs1015402 chr7:89913269 C/T cg25739043 chr7:89950458 NA -0.73 -7.31 -0.55 2.87e-11 Homocysteine levels; TGCT cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg05573699 chr3:52720067 GNL3;PBRM1 0.53 4.96 0.41 2.25e-6 Bipolar disorder; TGCT cis rs854765 0.964 rs854762 chr17:18009102 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.65 -6.31 -0.49 4.57e-9 Total body bone mineral density; TGCT cis rs4273100 0.688 rs4143829 chr17:19241505 G/A cg03910582 chr17:19030146 GRAPL -0.51 -6.21 -0.49 7.47e-9 Schizophrenia; TGCT cis rs57590327 0.528 rs13086292 chr3:81705368 G/A cg07356753 chr3:81810745 GBE1 -0.77 -6.97 -0.53 1.63e-10 Extraversion; TGCT cis rs72843506 0.722 rs74255387 chr17:20101383 G/A cg23224458 chr17:20280056 CCDC144C -0.56 -4.59 -0.38 1.09e-5 Schizophrenia; TGCT cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs16854884 0.837 rs989665 chr3:143792854 C/T cg06585982 chr3:143692056 C3orf58 0.62 4.81 0.4 4.32e-6 Economic and political preferences (feminism/equality); TGCT cis rs10744422 1.000 rs2061101 chr12:123348925 C/A cg25930673 chr12:123319894 HIP1R -0.87 -4.79 -0.4 4.66e-6 Schizophrenia; TGCT cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg13342137 chr4:2252803 MXD4 0.17 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg22029157 chr1:209979665 IRF6 0.78 8.98 0.63 3.67e-15 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs1127311 1.000 rs10908419 chr1:154567699 G/A cg17218026 chr1:154582156 ADAR 0.31 7.75 0.57 2.93e-12 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT trans rs1496653 0.602 rs35055753 chr3:23454366 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1801251 1.000 rs283486 chr2:233644223 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs1997103 1.000 rs12718956 chr7:55407763 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9858542 1.000 rs11130213 chr3:49712297 C/T cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1005277 0.505 rs7917943 chr10:38195811 T/A cg13531842 chr10:38383804 ZNF37A 0.38 4.55 0.38 1.24e-5 Extrinsic epigenetic age acceleration; TGCT cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg11494091 chr17:61959527 GH2 0.43 7.3 0.55 3.05e-11 Height; TGCT cis rs9296092 0.521 rs6929165 chr6:33515958 T/G cg13560919 chr6:33536144 NA -0.2 -4.91 -0.4 2.75e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs4319547 1.000 rs4319547 chr12:123079035 A/G cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.41 -0.44 3.16e-7 Body mass index; TGCT cis rs11098499 0.908 rs71614449 chr4:120387055 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg11003573 chr3:44754125 ZNF502 -0.46 -5.34 -0.43 4.34e-7 Depressive symptoms; TGCT cis rs7824557 0.564 rs35009431 chr8:11232788 G/A cg21775007 chr8:11205619 TDH -0.58 -5.42 -0.44 3.02e-7 Retinal vascular caliber; TGCT cis rs6089584 0.888 rs6061966 chr20:60607936 C/G cg06108461 chr20:60628389 TAF4 -0.69 -10.65 -0.69 3.24e-19 Body mass index; TGCT cis rs7017914 1.000 rs7007450 chr8:71640269 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs4722166 0.695 rs56061963 chr7:22800397 T/C cg26061582 chr7:22766209 IL6 0.48 6.25 0.49 6.15e-9 Lung cancer; TGCT cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs6722750 1.000 rs35573827 chr2:64394433 C/G cg22352474 chr2:64371530 PELI1 0.62 5.51 0.44 1.97e-7 Neuroticism; TGCT cis rs425277 0.606 rs262663 chr1:2084598 T/C cg24578937 chr1:2090814 PRKCZ 0.26 6.95 0.53 1.8e-10 Height; TGCT trans rs4332037 0.522 rs4721098 chr7:1881527 G/C cg25206134 chr2:45395956 NA -0.92 -7.78 -0.57 2.44e-12 Bipolar disorder; TGCT cis rs7666738 0.830 rs13108705 chr4:99044438 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2602836 0.830 rs2602874 chr4:100039396 A/T cg12011299 chr4:100065546 ADH4 0.4 5.72 0.46 7.52e-8 HDL cholesterol;HDL cholesterol levels; TGCT cis rs739496 0.894 rs11065898 chr12:111862575 C/T cg10833066 chr12:111807467 FAM109A 0.33 4.54 0.38 1.31e-5 Platelet count; TGCT trans rs7824557 0.547 rs6601570 chr8:11079367 G/A cg06636001 chr8:8085503 FLJ10661 -0.82 -7.42 -0.55 1.63e-11 Retinal vascular caliber; TGCT cis rs13191362 1.000 rs13212608 chr6:163032128 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.62 4.55 0.38 1.26e-5 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7086627 0.515 rs7078254 chr10:82212193 C/T cg01528321 chr10:82214614 TSPAN14 0.67 6.37 0.5 3.39e-9 Post bronchodilator FEV1; TGCT cis rs9807989 0.507 rs6758936 chr2:102991369 A/G cg03938978 chr2:103052716 IL18RAP -0.26 -5.22 -0.42 7.3e-7 Asthma; TGCT cis rs12478296 0.581 rs56142391 chr2:242992248 C/T cg06360820 chr2:242988706 NA -0.61 -4.72 -0.39 6.25e-6 Obesity-related traits; TGCT cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg12310025 chr6:25882481 NA -0.54 -5.47 -0.44 2.39e-7 Blood metabolite levels; TGCT cis rs7255045 0.743 rs10426080 chr19:12957850 A/G cg23899408 chr19:12877188 HOOK2 -0.6 -5.03 -0.41 1.67e-6 Mean corpuscular volume; TGCT cis rs2688608 0.901 rs2633312 chr10:75631755 T/A cg19442545 chr10:75533431 FUT11 -0.31 -5.04 -0.41 1.61e-6 Inflammatory bowel disease; TGCT cis rs9311474 0.713 rs352168 chr3:52237970 C/T cg07507251 chr3:52567010 NT5DC2 0.39 5.15 0.42 1e-6 Electroencephalogram traits; TGCT cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.05 0.48 1.59e-8 Alzheimer's disease; TGCT cis rs12477438 0.520 rs6542866 chr2:99764592 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs9357506 1.000 rs60277913 chr6:46302757 A/G cg21115430 chr6:46460003 NA -0.27 -5.47 -0.44 2.43e-7 Body mass index; TGCT cis rs17376456 1.000 rs12187701 chr5:93522290 A/G cg25358565 chr5:93447407 FAM172A 0.94 7.86 0.58 1.55e-12 Diabetic retinopathy; TGCT cis rs11650494 0.808 rs61286260 chr17:47433222 T/C cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs595982 0.559 rs73061643 chr19:49368151 A/G cg21252483 chr19:49399788 TULP2 -0.42 -6.39 -0.5 3.02e-9 Red cell distribution width; TGCT cis rs4240897 1.000 rs4240897 chr1:12042755 A/G cg13216073 chr1:12042593 MFN2 -0.16 -4.53 -0.38 1.38e-5 Tuberculosis; TGCT cis rs4870684 1.000 rs4870684 chr7:57699151 C/T cg01314568 chr7:57830625 NA -0.36 -4.63 -0.38 9.03e-6 Bipolar disorder and schizophrenia; TGCT cis rs10504229 0.906 rs113857287 chr8:58191683 T/C cg21724239 chr8:58056113 NA 0.38 5.09 0.42 1.31e-6 Developmental language disorder (linguistic errors); TGCT cis rs9443645 0.901 rs9443632 chr6:79664440 T/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.698 rs66911505 chr1:46823298 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7513165 0.935 rs2510 chr1:204161591 T/C cg12731349 chr1:204159619 KISS1 0.5 5.69 0.46 8.55e-8 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs877282 0.853 rs7092652 chr10:756109 G/A cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs10114408 0.959 rs10739962 chr9:96649758 A/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs80262450 1 rs80262450 chr18:12818922 G/A cg23544223 chr18:12777786 NA -0.62 -4.6 -0.38 1.04e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs8062405 1.000 rs4788099 chr16:28855727 A/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4689388 0.926 rs4689391 chr4:6280449 G/A cg25554036 chr4:6271136 WFS1 0.55 8.09 0.59 4.65e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9322193 0.923 rs9689723 chr6:149977071 C/A cg13206674 chr6:150067644 NUP43 0.51 4.47 0.37 1.75e-5 Lung cancer; TGCT cis rs1215050 0.740 rs700740 chr4:98976003 A/C cg17366294 chr4:99064904 C4orf37 -0.55 -5.8 -0.46 5.23e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2251381 0.741 rs2735966 chr21:30538174 G/A cg24692254 chr21:30365293 RNF160 0.74 7.47 0.56 1.28e-11 Selective IgA deficiency; TGCT cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg10108389 chr3:44770937 ZNF501 -0.46 -4.45 -0.37 1.88e-5 Depressive symptoms; TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg24503407 chr1:205819492 PM20D1 0.57 7.6 0.56 6.42e-12 Menarche (age at onset); TGCT cis rs10504229 0.679 rs111843870 chr8:58126798 A/G cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs9486719 1.000 rs12208011 chr6:96991105 G/A cg06623918 chr6:96969491 KIAA0776 -0.99 -7.99 -0.58 7.78e-13 Migraine;Coronary artery disease; TGCT cis rs8038465 0.615 rs6495075 chr15:73981005 A/G cg15420318 chr15:73925796 NPTN 0.68 7.53 0.56 9.28e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7937612 0.965 rs9633919 chr11:120249493 G/A cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.53 -0.38 1.37e-5 Intraocular pressure; TGCT cis rs614226 0.935 rs2235222 chr12:120892193 G/C cg01236616 chr12:121019343 POP5 -1.24 -12.17 -0.74 6.5e-23 Type 1 diabetes nephropathy; TGCT cis rs7267979 0.789 rs9927 chr20:25277244 A/G cg03522245 chr20:25566470 NINL 0.57 5.72 0.46 7.63e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7312933 0.703 rs10880268 chr12:42599122 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7584330 0.554 rs80151891 chr2:238398826 G/T cg14458575 chr2:238380390 NA 0.59 5.08 0.42 1.34e-6 Prostate cancer; TGCT cis rs12477438 1.000 rs11897712 chr2:99735697 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.46 -0.61 6.14e-14 Chronic sinus infection; TGCT cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg22963979 chr7:1858916 MAD1L1 -0.45 -7.37 -0.55 2.15e-11 Bipolar disorder and schizophrenia; TGCT cis rs111803315 1.000 rs112476368 chr14:59991452 A/G cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs12643440 0.538 rs6852278 chr4:17138490 A/C cg22650099 chr4:17144496 NA 0.47 4.79 0.4 4.7e-6 Metabolite levels (Pyroglutamine); TGCT cis rs6484504 0.576 rs2150213 chr11:31244634 A/G cg26647111 chr11:31128758 NA -0.34 -4.7 -0.39 6.78e-6 Red blood cell count; TGCT cis rs10479542 0.892 rs7723230 chr5:178980474 T/C cg19626725 chr5:178986131 RUFY1 0.45 5.7 0.46 8.11e-8 Lung cancer; TGCT cis rs7552404 1.000 rs12127402 chr1:76205643 C/A cg22875332 chr1:76189707 ACADM 0.77 9.42 0.65 3.17e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs713587 0.563 rs1529897 chr2:25086827 T/G cg01884057 chr2:25150051 NA 0.3 5.65 0.45 1.03e-7 Body mass index in non-asthmatics; TGCT cis rs7674212 0.541 rs2720458 chr4:104052963 C/G cg16532752 chr4:104119610 CENPE -0.61 -5.58 -0.45 1.44e-7 Type 2 diabetes; TGCT cis rs1215050 0.605 rs1817221 chr4:98615180 G/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9902453 0.904 rs12936302 chr17:28349476 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -7.56 -0.56 7.78e-12 Coffee consumption (cups per day); TGCT cis rs11096990 0.613 rs7690414 chr4:39212289 G/C cg20847110 chr4:39482781 LOC401127 0.16 4.58 0.38 1.13e-5 Cognitive function; TGCT cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg17971929 chr21:40555470 PSMG1 -0.71 -6.63 -0.51 9.09e-10 Cognitive function; TGCT cis rs12200560 0.505 rs211166 chr6:97068598 T/C cg06623918 chr6:96969491 KIAA0776 0.57 4.83 0.4 3.93e-6 Coronary heart disease; TGCT cis rs8177253 0.965 rs4854760 chr3:133498741 C/T cg16414030 chr3:133502952 NA 0.62 9.75 0.66 5.13e-17 Iron status biomarkers; TGCT cis rs7937682 0.921 rs1944119 chr11:111436387 A/G cg09085632 chr11:111637200 PPP2R1B 0.86 7.2 0.54 5.06e-11 Primary sclerosing cholangitis; TGCT cis rs617219 0.726 rs72764969 chr5:78451409 A/G cg05890484 chr5:78407552 BHMT 0.39 5.29 0.43 5.44e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7727544 0.816 rs274555 chr5:131722951 C/T cg21138405 chr5:131827807 IRF1 0.18 4.7 0.39 6.78e-6 Blood metabolite levels; TGCT cis rs853679 0.607 rs201002 chr6:27808192 A/G cg08798685 chr6:27730294 NA -0.32 -4.58 -0.38 1.1e-5 Depression; TGCT cis rs4148883 0.651 rs2851301 chr4:100010127 C/T cg12011299 chr4:100065546 ADH4 0.38 5.72 0.46 7.41e-8 Alcohol dependence; TGCT cis rs875971 0.862 rs1981799 chr7:65955559 T/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs12497850 0.931 rs7628719 chr3:48995487 C/T cg06212747 chr3:49208901 KLHDC8B 0.6 5.43 0.44 2.82e-7 Parkinson's disease; TGCT cis rs76878669 0.561 rs7107191 chr11:66140397 G/A cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.89e-9 Educational attainment (years of education); TGCT cis rs6912958 0.559 rs369674 chr6:88043402 C/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.73 -7.68 -0.57 4.16e-12 Monocyte percentage of white cells; TGCT cis rs9611565 0.546 rs34077262 chr22:42061639 A/G cg03806693 chr22:41940476 POLR3H 0.96 9.65 0.65 8.84e-17 Vitiligo; TGCT cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg09222892 chr1:25734099 RHCE -0.45 -7.34 -0.55 2.52e-11 Erythrocyte sedimentation rate; TGCT cis rs751728 0.965 rs2296743 chr6:33740025 C/T cg00334056 chr6:33755658 LEMD2 -0.25 -4.55 -0.38 1.25e-5 Crohn's disease; TGCT cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg20607798 chr8:58055168 NA 0.62 5.19 0.42 8.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs9534288 0.742 rs1022953 chr13:46649126 G/T cg15192986 chr13:46630673 CPB2 -0.53 -6.61 -0.51 1.03e-9 Blood protein levels; TGCT cis rs7666738 0.830 rs2865980 chr4:99027422 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7572733 0.515 rs1356542 chr2:198835702 G/T cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg13695892 chr22:41940480 POLR3H -0.91 -8.8 -0.62 9.77e-15 Vitiligo; TGCT cis rs10465746 0.967 rs7531537 chr1:84414924 C/T cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs2153535 0.547 rs9502720 chr6:8541362 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.61 0.45 1.23e-7 Motion sickness; TGCT cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg17554472 chr22:41940697 POLR3H 0.42 4.56 0.38 1.19e-5 Vitiligo; TGCT cis rs17030434 0.954 rs11724154 chr4:154753108 G/T cg14289246 chr4:154710475 SFRP2 -0.9 -7.05 -0.54 1.09e-10 Electrocardiographic conduction measures; TGCT cis rs7551345 0.653 rs6425719 chr1:31700777 T/C cg18936040 chr1:31673095 NA 0.27 4.44 0.37 1.98e-5 Schizophrenia; TGCT cis rs7826238 0.564 rs2921053 chr8:8319963 G/C cg08975724 chr8:8085496 FLJ10661 0.54 4.9 0.4 2.87e-6 Systolic blood pressure; TGCT cis rs8031584 1.000 rs35811129 chr15:31241346 G/A cg08704250 chr15:31115839 NA -0.36 -4.52 -0.38 1.43e-5 Huntington's disease progression; TGCT cis rs3935685 0.874 rs4886521 chr15:78000321 A/G cg03457338 chr15:78040120 NA -0.23 -5.88 -0.47 3.6e-8 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.931 rs6442130 chr3:48778027 A/G cg06212747 chr3:49208901 KLHDC8B 0.58 5.32 0.43 4.69e-7 Parkinson's disease; TGCT cis rs17376456 0.877 rs10073039 chr5:93467709 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs4953076 0.573 rs13008237 chr2:44404902 A/G cg04920474 chr2:44395004 PPM1B 0.56 5.58 0.45 1.47e-7 Height; TGCT cis rs7809950 0.598 rs2283038 chr7:106835410 C/T cg23024343 chr7:107201750 COG5 -0.44 -6.03 -0.48 1.74e-8 Coronary artery disease; TGCT cis rs7119 0.717 rs12915548 chr15:77818042 A/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs6770219 0.516 rs57136001 chr3:186140693 A/T cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.46 0.37 1.81e-5 Cerebrospinal T-tau levels; TGCT cis rs4700695 0.668 rs253212 chr5:65497553 C/T cg21114390 chr5:65439923 SFRS12 -0.81 -7.72 -0.57 3.34e-12 Facial morphology (factor 19); TGCT cis rs17253792 0.822 rs17253744 chr14:56161950 C/G cg01858014 chr14:56050164 KTN1 -0.36 -4.55 -0.38 1.24e-5 Putamen volume; TGCT cis rs12549902 1.000 rs12550613 chr8:41510260 G/C cg21772509 chr8:41503840 NKX6-3 0.87 10.06 0.67 9.27e-18 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs7107174 0.688 rs2063725 chr11:78133452 T/G cg12700464 chr11:78128424 GAB2 -0.68 -4.54 -0.38 1.33e-5 Testicular germ cell tumor; TGCT cis rs1552244 0.882 rs67762674 chr3:10014485 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.5 -0.5 1.76e-9 Alzheimer's disease; TGCT cis rs6543140 0.964 rs13393175 chr2:103078849 T/G cg09003973 chr2:102972529 NA 0.55 4.56 0.38 1.2e-5 Blood protein levels; TGCT cis rs3008870 1.000 rs3008873 chr1:67425770 G/A cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg11905131 chr22:24372483 LOC391322 0.69 5.52 0.44 1.87e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs4889855 0.511 rs9908700 chr17:78466594 A/G cg16591659 chr17:78472290 NA -0.35 -5.51 -0.44 1.99e-7 Fractional excretion of uric acid; TGCT trans rs3780486 0.846 rs10813960 chr9:33180362 C/T cg04842962 chr6:43655489 MRPS18A 1.12 12.06 0.73 1.25e-22 IgG glycosylation; TGCT cis rs8017423 0.935 rs11624890 chr14:90738165 T/A cg04374321 chr14:90722782 PSMC1 -0.75 -7.32 -0.55 2.75e-11 Mortality in heart failure; TGCT cis rs7192750 0.583 rs8046916 chr16:72047751 C/G cg14768367 chr16:72042858 DHODH -0.92 -4.89 -0.4 3.12e-6 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9311474 0.581 rs13621 chr3:52558133 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.74 0.52 5.28e-10 Electroencephalogram traits; TGCT cis rs12497850 0.863 rs4858799 chr3:48728204 G/C cg18654377 chr3:49208889 KLHDC8B -0.44 -6.06 -0.48 1.52e-8 Parkinson's disease; TGCT cis rs3733585 0.773 rs13107466 chr4:10019390 G/A cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg12516959 chr21:47718080 NA -0.35 -4.9 -0.4 2.88e-6 Testicular germ cell tumor; TGCT cis rs7611238 0.560 rs62287109 chr3:195053916 C/T cg27323046 chr3:195102265 ACAP2 0.35 4.75 0.39 5.5e-6 Body mass index; TGCT cis rs3862030 0.503 rs6584505 chr10:104254412 C/A cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs554111 0.656 rs10799680 chr1:21361181 C/T cg01072550 chr1:21505969 NA 0.36 5.44 0.44 2.77e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs10206020 0.885 rs11885392 chr2:1578182 C/A cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs7786808 0.608 rs7784758 chr7:158214386 A/G cg01191920 chr7:158217561 PTPRN2 -0.38 -5.74 -0.46 6.98e-8 Obesity-related traits; TGCT cis rs514406 0.621 rs881198 chr1:53196440 C/T cg25767906 chr1:53392781 SCP2 0.45 4.91 0.4 2.83e-6 Monocyte count; TGCT cis rs7772486 0.875 rs6914813 chr6:146397798 A/G cg13319975 chr6:146136371 FBXO30 -0.54 -4.72 -0.39 6.27e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12220238 1.000 rs7081350 chr10:75990328 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9467711 0.539 rs34436535 chr6:26370365 G/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1215050 0.755 rs7696354 chr4:98820330 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.57 0.45 1.54e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg11494091 chr17:61959527 GH2 -0.6 -16.42 -0.83 6.81e-33 Prudent dietary pattern; TGCT cis rs4730250 0.707 rs6977868 chr7:106790555 T/G cg02696742 chr7:106810147 HBP1 0.71 5.89 0.47 3.42e-8 Osteoarthritis; TGCT cis rs3733585 0.699 rs7694997 chr4:9947811 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.42 -0.55 1.62e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.830 rs9307218 chr4:99024885 T/C cg17366294 chr4:99064904 C4orf37 0.72 7.54 0.56 8.52e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.546 rs10440329 chr4:98903735 C/T cg17366294 chr4:99064904 C4orf37 0.63 5.54 0.45 1.72e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs2832077 0.527 rs59730679 chr21:30226244 T/C cg14791747 chr16:20752902 THUMPD1 1.09 12.67 0.75 4.09e-24 Cognitive test performance; TGCT cis rs66887589 0.616 rs11731675 chr4:120212514 T/C cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.15e-5 Diastolic blood pressure; TGCT cis rs7666738 0.830 rs2865951 chr4:99040191 C/T cg17366294 chr4:99064904 C4orf37 0.72 7.36 0.55 2.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs782590 0.902 rs7582278 chr2:55742924 C/G cg03859395 chr2:55845619 SMEK2 0.93 11.51 0.72 2.7e-21 Metabolic syndrome; TGCT cis rs11249608 0.636 rs13359549 chr5:178449178 T/A cg21905437 chr5:178450457 ZNF879 0.45 4.48 0.37 1.67e-5 Pubertal anthropometrics; TGCT cis rs10504229 0.683 rs7838958 chr8:58136968 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs1799949 0.683 rs55737636 chr17:41264739 C/T cg23758822 chr17:41437982 NA 0.71 6.94 0.53 1.89e-10 Menopause (age at onset); TGCT cis rs17125944 0.505 rs75661138 chr14:53259262 G/A cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs11997175 0.574 rs9642707 chr8:33645789 C/G ch.8.33884649F chr8:33765107 NA 0.28 4.53 0.38 1.35e-5 Body mass index; TGCT cis rs62012628 0.527 rs12438008 chr15:79084680 C/T cg04896959 chr15:78267971 NA -0.34 -5.85 -0.47 4.02e-8 Diastolic blood pressure; TGCT cis rs7666738 0.830 rs4345191 chr4:98945408 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13256369 0.851 rs12541477 chr8:8563895 G/A cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs9921338 1.000 rs8055427 chr16:11436883 T/A cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.32e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9733 0.569 rs11588404 chr1:150688529 C/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs7312933 0.703 rs10459290 chr12:42613290 T/G cg19980929 chr12:42632907 YAF2 0.43 5.72 0.46 7.48e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7666738 0.830 rs35560671 chr4:99069095 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11690935 0.851 rs10174055 chr2:172858214 C/T cg13550731 chr2:172543902 DYNC1I2 -0.89 -7.88 -0.58 1.41e-12 Schizophrenia; TGCT cis rs3617 0.573 rs9825230 chr3:52901974 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.53 5.09 0.42 1.29e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs11748023 0.605 rs185123 chr5:139517197 T/C cg01081189 chr5:139537190 NA 0.26 4.6 0.38 1.05e-5 Intelligence (multi-trait analysis); TGCT cis rs4839421 0.966 rs6677767 chr1:111022475 C/T cg06880108 chr1:111021908 CYMP -0.16 -4.96 -0.41 2.29e-6 Response to bupropion in depression; TGCT cis rs1218582 0.772 rs2174507 chr1:154887949 C/T cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs8077889 1.000 rs17674998 chr17:41879544 A/G cg26893861 chr17:41843967 DUSP3 1.12 13.18 0.76 2.48e-25 Triglycerides; TGCT cis rs7172809 0.573 rs28437977 chr15:77681453 C/T cg22256960 chr15:77711686 NA -0.5 -4.74 -0.39 5.82e-6 Glucose homeostasis traits; TGCT cis rs3806843 0.521 rs192231 chr5:140248539 C/T cg07102913 chr5:140593443 PCDHB13 0.47 4.54 0.38 1.29e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs1005277 0.522 rs200943 chr10:38148730 A/G cg13531842 chr10:38383804 ZNF37A -0.38 -4.55 -0.38 1.24e-5 Extrinsic epigenetic age acceleration; TGCT cis rs921968 0.510 rs591573 chr2:219478193 C/T cg02176678 chr2:219576539 TTLL4 0.48 6.79 0.52 4.05e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs1949733 1.000 rs2688233 chr4:8491885 T/C cg13073564 chr4:8508604 NA -0.5 -5.53 -0.44 1.84e-7 Response to antineoplastic agents; TGCT cis rs2075371 0.933 rs2544191 chr7:133954248 A/G cg11752832 chr7:134001865 SLC35B4 0.68 5.89 0.47 3.32e-8 Mean platelet volume; TGCT cis rs12142240 0.698 rs56344958 chr1:46814518 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg18305652 chr10:134549665 INPP5A 0.34 5.84 0.46 4.32e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12615966 0.858 rs17030286 chr2:105381220 T/G cg16465502 chr2:105461796 NA 0.81 4.47 0.37 1.76e-5 Pancreatic cancer; TGCT cis rs36051895 0.593 rs12682970 chr9:5168137 C/T cg02405213 chr9:5042618 JAK2 -0.69 -8.7 -0.62 1.67e-14 Pediatric autoimmune diseases; TGCT cis rs2692947 0.630 rs1168966 chr2:96798510 G/A cg23100626 chr2:96804247 ASTL 0.41 5.03 0.41 1.65e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs3902035 0.964 rs17349301 chr6:119002581 A/T cg07617317 chr6:118971624 C6orf204 -0.49 -5.7 -0.46 8.29e-8 QT interval; TGCT cis rs11025559 0.617 rs11025592 chr11:20534286 T/C cg19653624 chr11:20408972 PRMT3 -0.76 -6.64 -0.51 8.98e-10 Pursuit maintenance gain; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg10150615 chr22:24372951 LOC391322 0.86 7.67 0.57 4.36e-12 S-phenylmercapturic acid levels in smokers; TGCT cis rs2535633 0.631 rs11915851 chr3:53096047 C/T cg10802521 chr3:52805072 NEK4 -0.5 -5.38 -0.43 3.6e-7 Body mass index; TGCT cis rs9393692 0.875 rs9393690 chr6:26271713 A/T cg13736514 chr6:26305472 NA -0.39 -5.6 -0.45 1.31e-7 Educational attainment; TGCT cis rs5750830 0.594 rs6001568 chr22:39775786 G/A cg24399712 chr22:39784796 NA -0.95 -11.19 -0.71 1.59e-20 Intelligence (multi-trait analysis); TGCT cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg26116260 chr4:7069785 GRPEL1 1.13 11.1 0.71 2.59e-20 Monocyte percentage of white cells; TGCT cis rs6484504 0.576 rs286653 chr11:31227824 C/T cg26647111 chr11:31128758 NA -0.34 -4.68 -0.39 7.25e-6 Red blood cell count; TGCT cis rs7666738 0.830 rs13102652 chr4:99006737 T/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7000551 0.725 rs2469756 chr8:22360423 G/A cg12081754 chr8:22256438 SLC39A14 0.28 4.6 0.38 1.04e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9633740 0.773 rs1870148 chr10:82271341 G/A cg01528321 chr10:82214614 TSPAN14 0.93 6.74 0.52 5.44e-10 Post bronchodilator FEV1; TGCT cis rs922182 1.000 rs922182 chr15:64277642 C/T cg02919090 chr15:64263738 DAPK2 0.29 5.44 0.44 2.72e-7 Blood protein levels; TGCT cis rs34526934 0.608 rs13017511 chr2:177035395 A/G cg16982199 chr2:177418664 NA -0.48 -4.49 -0.37 1.58e-5 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs1801251 1.000 rs2675974 chr2:233727071 A/G cg08000102 chr2:233561755 GIGYF2 0.63 6.48 0.5 1.92e-9 Coronary artery disease; TGCT cis rs2730245 0.527 rs712199 chr7:158662250 A/G cg11984989 chr7:158649758 WDR60 0.98 7.84 0.58 1.81e-12 Height; TGCT cis rs9393692 0.645 rs11756673 chr6:26323505 A/G cg13736514 chr6:26305472 NA -0.45 -6.67 -0.51 7.52e-10 Educational attainment; TGCT cis rs2836974 0.644 rs9978775 chr21:40694526 A/G cg06238570 chr21:40685208 BRWD1 -0.79 -8.46 -0.6 6.28e-14 Cognitive function; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg20111269 chr12:107972364 BTBD11 -0.88 -7.09 -0.54 8.76e-11 Follicular lymphoma; TGCT cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg17054783 chr10:134559939 INPP5A 0.27 5.15 0.42 1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs1814175 0.727 rs2140597 chr11:49873946 G/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs2233152 0.572 rs10403040 chr19:41296046 A/T cg11601297 chr19:41224147 ITPKC;ADCK4 -0.49 -4.73 -0.39 5.94e-6 Kawasaki disease; TGCT cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg24250549 chr1:154909240 PMVK -0.66 -6.53 -0.51 1.51e-9 Prostate cancer; TGCT cis rs77741769 0.571 rs11065300 chr12:121298512 G/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs12681287 0.752 rs10104138 chr8:87247659 G/A cg27223183 chr8:87520930 FAM82B -0.81 -5.77 -0.46 5.91e-8 Caudate activity during reward; TGCT cis rs2180341 0.597 rs11154397 chr6:127646649 G/C cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs17767294 0.708 rs72848769 chr6:27918379 G/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs10992471 0.603 rs11788523 chr9:95256593 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.47 -0.44 2.4e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs72781680 0.846 rs72782114 chr2:24025740 G/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs1153858 1.000 rs56850226 chr15:45633118 T/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs6089584 0.889 rs6142923 chr20:60596617 C/T cg16423285 chr20:60520624 NA 0.61 6.55 0.51 1.39e-9 Body mass index; TGCT cis rs9549367 0.789 rs34448227 chr13:113884754 A/C cg18105134 chr13:113819100 PROZ -0.34 -5.44 -0.44 2.75e-7 Platelet distribution width; TGCT cis rs6570726 0.935 rs434298 chr6:145846873 G/A cg23711669 chr6:146136114 FBXO30 0.67 6.41 0.5 2.7e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 0.966 rs2098152 chr4:17684392 G/T cg10189774 chr4:17578691 LAP3 0.52 4.71 0.39 6.54e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2075165 0.901 rs7542045 chr1:156246473 G/C cg16558208 chr1:156270281 VHLL 0.27 4.83 0.4 3.87e-6 Tonsillectomy; TGCT cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg17971929 chr21:40555470 PSMG1 0.95 9.18 0.64 1.22e-15 Cognitive function; TGCT cis rs10193935 1.000 rs72796507 chr2:42409840 A/G cg27598129 chr2:42591480 NA -0.4 -5.15 -0.42 9.93e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7192750 0.617 rs9929256 chr16:72040032 A/C cg14768367 chr16:72042858 DHODH 0.89 5.06 0.41 1.48e-6 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs6665290 0.835 rs11578479 chr1:227210888 A/T cg10327440 chr1:227177885 CDC42BPA -0.91 -16.3 -0.83 1.24e-32 Myeloid white cell count; TGCT cis rs1577917 0.771 rs4351223 chr6:86237797 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 5.32 0.43 4.64e-7 Response to antipsychotic treatment; TGCT cis rs8032315 0.965 rs1894400 chr15:91428955 C/T cg05180856 chr15:91428056 FES 0.25 4.62 0.38 9.41e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg03161606 chr19:29218774 NA 0.6 5.84 0.46 4.28e-8 Methadone dose in opioid dependence; TGCT cis rs763121 0.853 rs5750668 chr22:39079964 T/C cg06022373 chr22:39101656 GTPBP1 0.74 7.28 0.55 3.38e-11 Menopause (age at onset); TGCT trans rs3808502 0.563 rs12549150 chr8:11422936 C/T cg15556689 chr8:8085844 FLJ10661 0.79 7.18 0.54 5.71e-11 Neuroticism; TGCT cis rs208520 0.690 rs207081 chr6:66773742 A/G cg07460842 chr6:66804631 NA -0.96 -10.25 -0.68 3.18e-18 Exhaled nitric oxide output; TGCT cis rs7635838 0.586 rs379241 chr3:11291565 G/A cg00170343 chr3:11313890 ATG7 0.64 6.43 0.5 2.5e-9 HDL cholesterol; TGCT cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg10047753 chr17:41438598 NA 0.92 8.97 0.63 3.79e-15 Menopause (age at onset); TGCT cis rs734999 0.572 rs3748816 chr1:2526746 A/G cg18854424 chr1:2615690 NA 0.5 5.78 0.46 5.64e-8 Ulcerative colitis; TGCT cis rs8072100 0.790 rs34200664 chr17:45744652 C/T cg10024583 chr17:45772800 TBKBP1 -0.43 -4.47 -0.37 1.72e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7772486 0.875 rs10457796 chr6:146416087 T/G cg23711669 chr6:146136114 FBXO30 0.89 9.4 0.65 3.51e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs9992391 chr4:98916052 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.99 0.41 1.98e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.808 rs114563746 chr2:43760880 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.81 -0.4 4.35e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Intelligence (multi-trait analysis); TGCT cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.4 -4.76 -0.39 5.24e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg10819733 chr22:24237672 NA -0.28 -4.59 -0.38 1.09e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.830 rs1967979 chr4:98966201 G/T cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 1.000 rs12192261 chr6:66985268 A/G cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs2180341 0.782 rs6924274 chr6:127721556 T/A cg27446573 chr6:127587934 RNF146 0.8 7.08 0.54 9.53e-11 Breast cancer; TGCT cis rs9393777 0.513 rs7740197 chr6:26663478 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 0.62 5.71 0.46 7.95e-8 Intelligence (multi-trait analysis); TGCT cis rs7954584 0.567 rs11043233 chr12:122330733 C/T cg21016266 chr12:122356598 WDR66 0.51 6.46 0.5 2.15e-9 Mean corpuscular volume; TGCT cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.86 -10.23 -0.68 3.5e-18 Colorectal cancer; TGCT cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg13342137 chr4:2252803 MXD4 0.17 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg06481639 chr22:41940642 POLR3H 0.75 6.64 0.51 8.81e-10 Vitiligo; TGCT cis rs6570726 0.875 rs416243 chr6:145868081 A/T cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6424115 1.000 rs4649115 chr1:24155731 A/G cg15997130 chr1:24165203 NA -0.92 -10.57 -0.69 5.26e-19 Immature fraction of reticulocytes; TGCT cis rs2677744 0.626 rs12905855 chr15:91498429 G/C cg23684204 chr15:91497937 RCCD1 0.39 5.92 0.47 2.91e-8 Attention deficit hyperactivity disorder; TGCT cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg03806693 chr22:41940476 POLR3H -1.01 -11.18 -0.71 1.71e-20 Vitiligo; TGCT cis rs1023500 1.000 rs10154646 chr22:42331409 G/C cg04692870 chr22:42525206 CYP2D6 -0.35 -5.27 -0.43 5.73e-7 Schizophrenia; TGCT cis rs597539 0.652 rs686390 chr11:68656077 T/C cg06028808 chr11:68637592 NA 0.52 6.63 0.51 9.23e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs910316 0.967 rs4899549 chr14:75647494 G/A cg08847533 chr14:75593920 NEK9 -0.91 -9.96 -0.67 1.56e-17 Height; TGCT cis rs853679 0.546 rs483143 chr6:27846744 G/C cg08798685 chr6:27730294 NA -0.36 -5.06 -0.41 1.45e-6 Depression; TGCT cis rs9814567 0.679 rs1880379 chr3:134330612 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs514406 0.861 rs6588443 chr1:53250650 G/A cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs9653442 0.712 rs7582731 chr2:100686486 T/C cg22139774 chr2:100720529 AFF3 -0.43 -7.77 -0.57 2.58e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4654899 0.833 rs12135548 chr1:21084367 G/A cg01072550 chr1:21505969 NA -0.49 -8.03 -0.59 6.29e-13 Superior frontal gyrus grey matter volume; TGCT cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg03517284 chr6:25882590 NA -0.68 -6.01 -0.47 1.94e-8 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg11502198 chr6:26597334 ABT1 0.54 4.87 0.4 3.4e-6 Intelligence (multi-trait analysis); TGCT cis rs4891159 0.790 rs10514217 chr18:74144939 A/G cg24786174 chr18:74118243 ZNF516 -0.46 -4.86 -0.4 3.49e-6 Longevity; TGCT cis rs763014 0.898 rs4984897 chr16:632180 G/C cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs6496667 0.600 rs28674812 chr15:91077809 G/T cg22089800 chr15:90895588 ZNF774 0.66 4.76 0.39 5.28e-6 Rheumatoid arthritis; TGCT cis rs7772486 0.754 rs9497434 chr6:146260753 C/T cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT trans rs208520 0.507 rs7755710 chr6:66783355 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.09 -16.9 -0.84 5.6e-34 Exhaled nitric oxide output; TGCT trans rs1974653 0.672 rs9606244 chr22:20082881 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg25151919 chr3:44754333 ZNF502 -0.4 -4.62 -0.38 9.54e-6 Depressive symptoms; TGCT cis rs765787 0.530 rs2413776 chr15:45544170 A/G cg24006582 chr15:45444508 DUOX1 -0.26 -5.61 -0.45 1.24e-7 Uric acid levels; TGCT cis rs1008375 1.000 rs10027755 chr4:17615954 G/C cg18681998 chr4:17616180 MED28 1.01 11.57 0.72 1.95e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4664308 0.935 rs6731260 chr2:160977769 A/G cg03641300 chr2:160917029 PLA2R1 -0.28 -6.94 -0.53 1.96e-10 Idiopathic membranous nephropathy; TGCT cis rs7552404 1.000 rs11161510 chr1:76210289 A/G cg22875332 chr1:76189707 ACADM -0.78 -9.44 -0.65 2.8e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7659604 0.560 rs769238 chr4:122744942 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.26 -0.43 6.07e-7 Type 2 diabetes; TGCT cis rs2180341 0.814 rs6919082 chr6:127737888 T/G cg27446573 chr6:127587934 RNF146 0.87 7.93 0.58 1.08e-12 Breast cancer; TGCT cis rs950776 0.518 rs12591557 chr15:78811732 A/G cg06917634 chr15:78832804 PSMA4 0.97 9.62 0.65 1.05e-16 Sudden cardiac arrest; TGCT cis rs12602901 0.528 rs12601694 chr17:4980381 C/T cg07834574 chr17:4802847 CHRNE;C17orf107 -0.46 -4.53 -0.38 1.36e-5 Blood metabolite levels; TGCT cis rs76419734 0.558 rs4326019 chr4:106527381 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.82 4.66 0.39 7.91e-6 Post bronchodilator FEV1; TGCT cis rs4631830 0.900 rs10763588 chr10:51539762 G/T cg10326726 chr10:51549505 MSMB -0.26 -5.3 -0.43 5.07e-7 Prostate-specific antigen levels; TGCT cis rs7829975 0.902 rs777707 chr8:8584344 A/G cg08975724 chr8:8085496 FLJ10661 0.51 4.53 0.38 1.38e-5 Mood instability; TGCT cis rs17376456 0.542 rs1982439 chr5:93160560 C/G cg25358565 chr5:93447407 FAM172A -0.75 -6.28 -0.49 5.26e-9 Diabetic retinopathy; TGCT cis rs7772486 0.806 rs4243478 chr6:146284560 A/G cg05347473 chr6:146136440 FBXO30 -0.55 -5.41 -0.44 3.16e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg00684032 chr4:1343700 KIAA1530 0.21 4.53 0.38 1.39e-5 Obesity-related traits; TGCT cis rs9902453 1.000 rs9896062 chr17:28357047 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs74233809 0.636 rs284861 chr10:104572276 A/G cg05855489 chr10:104503620 C10orf26 -0.73 -4.99 -0.41 1.96e-6 Birth weight; TGCT cis rs3820068 0.677 rs72643691 chr1:15856251 T/C cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs644799 0.610 rs1255179 chr11:95472097 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.51 5.05 0.41 1.55e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7772486 0.790 rs3924499 chr6:146232978 A/T cg23711669 chr6:146136114 FBXO30 -0.87 -10.04 -0.67 1.01e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs208520 0.754 rs7753158 chr6:66875633 A/C cg07460842 chr6:66804631 NA -0.88 -8.65 -0.61 2.21e-14 Exhaled nitric oxide output; TGCT cis rs3780378 0.935 rs6476939 chr9:5084837 T/A cg03508284 chr9:4985524 JAK2 -0.49 -4.6 -0.38 1.03e-5 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs6089829 1.000 rs6089828 chr20:61668998 C/T cg08045932 chr20:61659980 NA 0.49 9.25 0.64 8.42e-16 Prostate cancer (SNP x SNP interaction); TGCT trans rs7618501 0.933 rs1128535 chr3:49866392 C/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs6545883 0.929 rs1186711 chr2:61688505 T/C cg15711740 chr2:61764176 XPO1 -0.6 -5.5 -0.44 2.03e-7 Tuberculosis; TGCT cis rs4699052 0.635 rs6821137 chr4:104246093 G/C cg16532752 chr4:104119610 CENPE -0.55 -5.43 -0.44 2.87e-7 Testicular germ cell tumor; TGCT cis rs7208859 0.673 rs216420 chr17:28938508 C/T cg04154034 chr17:28927549 LRRC37B2 0.74 4.56 0.38 1.22e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2073300 1.000 rs6137983 chr20:23469465 C/A cg09953122 chr20:23471693 CST8 -0.7 -4.76 -0.39 5.31e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7647973 0.731 rs7617480 chr3:49210732 G/T cg05785598 chr3:49045655 WDR6 -0.45 -4.98 -0.41 2.1e-6 Menarche (age at onset); TGCT cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs554111 0.656 rs12567861 chr1:21395133 C/T cg01072550 chr1:21505969 NA 0.36 5.46 0.44 2.51e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs7666738 0.830 rs13118945 chr4:98968586 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs1150668 0.764 rs9368565 chr6:28345210 C/T cg19488431 chr6:28601329 NA -0.2 -4.51 -0.38 1.49e-5 Pubertal anthropometrics; TGCT cis rs6952808 0.531 rs3778998 chr7:2180753 C/A cg04267008 chr7:1944627 MAD1L1 -0.38 -5.0 -0.41 1.94e-6 Bipolar disorder and schizophrenia; TGCT cis rs2290402 0.536 rs4690204 chr4:881195 C/T cg23332689 chr4:987652 IDUA;SLC26A1 0.33 5.0 0.41 1.94e-6 Type 2 diabetes; TGCT cis rs4849845 0.653 rs3933618 chr2:121035552 T/G cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg06618935 chr21:46677482 NA -0.35 -5.44 -0.44 2.72e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12477438 0.798 rs4622780 chr2:99631760 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.75 -0.46 6.58e-8 Chronic sinus infection; TGCT cis rs9467773 1.000 rs1321480 chr6:26532742 A/G cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.18e-23 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.932 rs2836953 chr21:40617483 G/A cg17971929 chr21:40555470 PSMG1 0.98 9.65 0.65 9.11e-17 Cognitive function; TGCT cis rs13242816 1.000 rs2188243 chr7:116109293 G/A cg16553024 chr7:116138462 CAV2 -0.44 -4.53 -0.38 1.34e-5 P wave duration; TGCT cis rs6671200 1.000 rs60929805 chr1:95646386 C/T cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs9911578 0.967 rs4076229 chr17:56937256 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs908922 0.676 rs11205018 chr1:152496249 T/G cg20991723 chr1:152506922 NA 0.46 6.26 0.49 5.7e-9 Hair morphology; TGCT cis rs2204008 0.774 rs11616004 chr12:38278822 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs3741404 0.620 rs11231722 chr11:63967770 C/G cg00022866 chr11:64108440 CCDC88B 0.24 4.54 0.38 1.29e-5 Platelet count; TGCT cis rs2439831 0.571 rs689883 chr15:43812596 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.3 0.43 5.23e-7 Lung cancer in ever smokers; TGCT trans rs12191082 0.591 rs12664748 chr6:46913149 T/G cg15621338 chr7:128577916 IRF5 -1.27 -7.2 -0.54 5.04e-11 Mean platelet volume; TGCT cis rs7213347 0.611 rs1231207 chr17:2125450 A/C cg13315690 chr17:1944831 OVCA2;DPH1 -0.38 -4.83 -0.4 3.98e-6 Total body bone mineral density; TGCT cis rs7772486 0.558 rs9376965 chr6:146130055 G/A cg23711669 chr6:146136114 FBXO30 0.73 6.75 0.52 5.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6460942 0.730 rs7780477 chr7:12233750 G/C cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs11249608 0.548 rs7733072 chr5:178456007 A/G cg01312482 chr5:178451176 ZNF879 -0.48 -4.77 -0.39 5.15e-6 Pubertal anthropometrics; TGCT trans rs6089829 0.855 rs6062781 chr20:61667128 G/A cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7681440 0.904 rs6817001 chr4:90766019 C/T cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs2019216 0.542 rs8073228 chr17:21909838 C/G cg22648282 chr17:21454238 C17orf51 -0.59 -5.89 -0.47 3.46e-8 Pelvic organ prolapse; TGCT cis rs59698941 0.527 rs7719428 chr5:132180919 C/G cg27099455 chr5:132201840 GDF9;UQCRQ -0.29 -4.93 -0.4 2.59e-6 Apolipoprotein A-IV levels; TGCT cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg11494091 chr17:61959527 GH2 0.42 7.46 0.56 1.29e-11 Height; TGCT cis rs9325144 0.624 rs7979541 chr12:39129679 T/C cg26384229 chr12:38710491 ALG10B -0.62 -5.85 -0.47 4.06e-8 Morning vs. evening chronotype; TGCT cis rs2816062 0.786 rs735946 chr1:18901323 T/C cg18795169 chr1:18902165 NA -0.6 -13.84 -0.78 6.55e-27 Urate levels in lean individuals; TGCT cis rs6570726 0.791 rs408443 chr6:145874643 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10789207 0.672 rs17472890 chr1:66991492 A/T cg22855438 chr1:67395917 MIER1 0.64 4.53 0.38 1.38e-5 Resting heart rate; TGCT cis rs17767294 0.708 rs72848760 chr6:27886877 T/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 7.8 0.57 2.16e-12 Platelet count; TGCT cis rs35883536 0.528 rs10783138 chr1:101031061 C/T cg10298815 chr1:101004474 GPR88 0.25 4.68 0.39 7.46e-6 Monocyte count; TGCT cis rs7267979 1.000 rs4815411 chr20:25350223 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs6964587 1.000 rs2075881 chr7:91734552 T/C cg17063962 chr7:91808500 NA 0.88 9.58 0.65 1.33e-16 Breast cancer; TGCT cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg10047753 chr17:41438598 NA 0.96 9.49 0.65 2.15e-16 Menopause (age at onset); TGCT trans rs1496653 0.602 rs35587590 chr3:23344579 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2013441 0.965 rs9896221 chr17:20180337 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs10875746 0.903 rs10875738 chr12:48473739 T/A cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs9486715 0.867 rs4598081 chr6:96975227 A/G cg06623918 chr6:96969491 KIAA0776 1.09 15.75 0.82 2.31e-31 Headache; TGCT cis rs2718812 0.766 rs11924101 chr3:133394478 T/G cg08048268 chr3:133502702 NA -0.38 -4.7 -0.39 6.68e-6 Iron status biomarkers; TGCT cis rs11098499 0.754 rs938056 chr4:120237453 C/T cg09307838 chr4:120376055 NA 0.57 5.25 0.43 6.47e-7 Corneal astigmatism; TGCT cis rs950169 0.887 rs71395453 chr15:85113490 G/C cg12863693 chr15:85201151 NMB 0.39 4.44 0.37 1.99e-5 Schizophrenia; TGCT cis rs473651 0.935 rs10170056 chr2:239339291 G/C cg18131467 chr2:239335373 ASB1 0.95 9.87 0.66 2.62e-17 Multiple system atrophy; TGCT cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs72634258 0.554 rs12745962 chr1:7919825 C/T cg26816564 chr1:7831052 VAMP3 0.64 4.94 0.41 2.46e-6 Inflammatory bowel disease; TGCT cis rs28927680 0.655 rs11820589 chr11:116633862 G/A cg01124546 chr11:117515332 DSCAML1 -0.45 -4.81 -0.4 4.27e-6 Lipid traits;Triglycerides; TGCT cis rs7666738 0.830 rs13138051 chr4:99050367 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 0.862 rs10282433 chr7:65721439 G/A cg11764359 chr7:65958608 NA -0.57 -5.12 -0.42 1.12e-6 Aortic root size; TGCT cis rs4455778 0.659 rs7795168 chr7:49057274 T/C cg26309511 chr7:48887640 NA 0.44 5.12 0.42 1.13e-6 Lung cancer in never smokers; TGCT cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs12681287 0.547 rs4961197 chr8:87512436 T/C cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs2576037 0.583 rs501062 chr18:44411135 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.61 -0.38 9.88e-6 Personality dimensions; TGCT cis rs7173389 0.867 rs74022964 chr15:73677264 C/T cg02916102 chr15:74658244 CYP11A1 -0.81 -4.56 -0.38 1.19e-5 Resting heart rate; TGCT cis rs9457247 1.000 rs409356 chr6:167405226 T/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs7267979 1.000 rs422424 chr20:25445446 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs61990749 0.597 rs8016447 chr14:78222068 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs911555 0.655 rs10149470 chr14:104017953 A/G cg12935359 chr14:103987150 CKB -0.31 -4.59 -0.38 1.06e-5 Intelligence (multi-trait analysis); TGCT cis rs2933343 1.000 rs876756 chr3:128627623 G/A cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs7845219 0.539 rs13271644 chr8:95853948 A/G cg16049864 chr8:95962084 TP53INP1 -0.55 -6.3 -0.49 4.83e-9 Type 2 diabetes; TGCT cis rs9926296 0.512 rs11076626 chr16:89865103 T/A cg03388025 chr16:89894329 SPIRE2 0.48 8.33 0.6 1.26e-13 Vitiligo; TGCT cis rs2594989 0.887 rs7624357 chr3:11412882 C/G cg00170343 chr3:11313890 ATG7 0.63 4.72 0.39 6.17e-6 Circulating chemerin levels; TGCT cis rs2235649 0.585 rs7201108 chr16:1940283 G/C cg02432467 chr16:1963432 HS3ST6 -0.33 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT trans rs8073060 0.533 rs178736 chr17:33928158 G/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.04 -0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9914544 0.545 rs3826380 chr17:18793225 A/G cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg10560079 chr2:191398806 TMEM194B 0.38 5.53 0.45 1.77e-7 Pulse pressure; TGCT cis rs73001065 0.892 rs58542926 chr19:19379549 C/T cg03709012 chr19:19516395 GATAD2A 1.05 4.86 0.4 3.45e-6 LDL cholesterol; TGCT cis rs35306767 1.000 rs35306767 chr10:989437 A/T cg26597838 chr10:835615 NA 0.61 8.05 0.59 5.89e-13 Eosinophil percentage of granulocytes; TGCT cis rs9467603 0.800 rs1892252 chr6:25772639 C/G cg27579711 chr6:26172931 NA 0.65 4.9 0.4 2.97e-6 Intelligence (multi-trait analysis); TGCT cis rs4713118 0.699 rs200969 chr6:27859453 T/C cg18675097 chr6:28227127 NKAPL -0.35 -4.61 -0.38 9.67e-6 Parkinson's disease; TGCT cis rs10883723 0.810 rs11191304 chr10:104255284 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2456568 0.802 rs7101791 chr11:93638998 A/G cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.09e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.04 11.55 0.72 2.13e-21 Height; TGCT cis rs2239547 0.522 rs2581780 chr3:53058960 C/T cg10802521 chr3:52805072 NEK4 0.62 5.53 0.44 1.85e-7 Schizophrenia; TGCT trans rs2727020 0.894 rs1880438 chr11:49370698 A/G cg03929089 chr4:120376271 NA -0.67 -6.99 -0.53 1.52e-10 Coronary artery disease; TGCT cis rs9549367 0.713 rs3024744 chr13:113821477 A/C cg09473364 chr13:112927190 NA -0.3 -4.47 -0.37 1.71e-5 Platelet distribution width; TGCT cis rs1218582 0.772 rs4240875 chr1:154885782 G/A cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs2235642 0.685 rs2667681 chr16:1653206 C/T cg07639376 chr16:1584516 IFT140;TMEM204 -0.29 -4.97 -0.41 2.22e-6 Coronary artery disease; TGCT cis rs2307449 0.964 rs758130 chr15:89873797 A/G cg01877814 chr15:89879097 POLG 0.32 4.55 0.38 1.26e-5 Menopause (age at onset); TGCT cis rs7959452 0.868 rs12812860 chr12:69746671 T/C cg14784868 chr12:69753453 YEATS4 0.7 7.22 0.54 4.55e-11 Blood protein levels; TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg06873352 chr17:61820015 STRADA 0.58 6.36 0.5 3.51e-9 Prudent dietary pattern; TGCT cis rs7221109 0.560 rs758630 chr17:38869305 T/A cg07480653 chr17:39868082 GAST -0.24 -5.09 -0.42 1.3e-6 Type 1 diabetes; TGCT cis rs6582630 0.519 rs11514078 chr12:38408817 G/C cg13010199 chr12:38710504 ALG10B 0.67 5.35 0.43 4.04e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs7208859 0.673 rs61348930 chr17:29221763 C/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg12756686 chr19:29218302 NA 0.77 6.61 0.51 1.01e-9 Methadone dose in opioid dependence; TGCT cis rs7308116 0.967 rs10778578 chr12:108190020 T/C cg19508191 chr12:109124361 CORO1C -0.46 -4.6 -0.38 1.04e-5 Pelvic organ prolapse (moderate/severe); TGCT cis rs68170813 0.559 rs12537011 chr7:107027833 G/A cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs1801251 1.000 rs12990821 chr2:233617585 C/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs13242816 1.000 rs62471189 chr7:116101588 G/A cg02799643 chr7:116139180 CAV2 -0.44 -5.12 -0.42 1.11e-6 P wave duration; TGCT cis rs910316 1.000 rs12889472 chr14:75543979 A/G cg23033748 chr14:75592666 NEK9 0.28 4.76 0.39 5.28e-6 Height; TGCT cis rs11785400 1.000 rs4736342 chr8:143735190 A/G cg10596483 chr8:143751796 JRK 0.55 5.94 0.47 2.68e-8 Schizophrenia; TGCT cis rs12765878 1.000 rs35223321 chr10:105646395 C/T cg11005552 chr10:105648138 OBFC1 0.44 7.69 0.57 4.01e-12 Coronary artery disease; TGCT cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.925 rs4809270 chr20:61676709 C/A cg03213289 chr20:61660250 NA 0.73 9.58 0.65 1.31e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7208859 0.623 rs383436 chr17:28959179 A/G cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs796364 0.616 rs2103094 chr2:200687954 T/C cg17644776 chr2:200775616 C2orf69 0.35 4.96 0.41 2.29e-6 Schizophrenia; TGCT cis rs7017914 0.905 rs2639898 chr8:71920310 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.05 -0.41 1.52e-6 Bone mineral density; TGCT cis rs1475911 1.000 rs12482477 chr21:43517233 T/A cg14562523 chr21:43528734 C21orf128;UMODL1 -0.24 -4.79 -0.4 4.7e-6 IgG glycosylation; TGCT cis rs6088580 0.634 rs4258875 chr20:32924895 C/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.84 -0.4 3.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs1971762 0.545 rs9788134 chr12:54046067 A/T cg16917193 chr12:54089295 NA 1.07 11.43 0.72 4.28e-21 Height; TGCT cis rs7095607 0.606 rs7100561 chr10:69958472 G/A cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs6430585 0.528 rs3112496 chr2:136711064 C/T cg07169764 chr2:136633963 MCM6 1.21 11.87 0.73 3.62e-22 Corneal structure; TGCT cis rs2730245 0.527 rs2527187 chr7:158716912 T/C cg11984989 chr7:158649758 WDR60 -1.01 -7.88 -0.58 1.4e-12 Height; TGCT cis rs709400 0.663 rs55723020 chr14:103991401 G/A cg12935359 chr14:103987150 CKB -0.39 -5.77 -0.46 5.87e-8 Body mass index; TGCT cis rs617219 0.710 rs10474578 chr5:78542290 T/C cg09550809 chr5:78407562 BHMT 0.37 5.24 0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10927875 0.722 rs6696912 chr1:16338474 T/C cg14742211 chr1:16348397 CLCNKA 0.19 4.53 0.38 1.37e-5 Dilated cardiomyopathy; TGCT cis rs4906332 0.966 rs35799018 chr14:103893475 G/A cg26031613 chr14:104095156 KLC1 -0.54 -4.82 -0.4 4.04e-6 Coronary artery disease; TGCT cis rs752092 1.000 rs8033360 chr15:101778710 C/A cg25114630 chr15:101792522 CHSY1 0.57 5.54 0.45 1.71e-7 Corneal structure; TGCT cis rs208520 0.690 rs9345764 chr6:66820597 C/T cg07460842 chr6:66804631 NA -0.96 -9.89 -0.66 2.33e-17 Exhaled nitric oxide output; TGCT cis rs1018836 0.923 rs4735230 chr8:91574184 G/C cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs66569888 0.507 rs17032699 chr2:106886471 A/G cg16099169 chr2:106886729 NA -0.48 -6.16 -0.48 9.37e-9 Facial morphology (factor 23); TGCT cis rs2115630 1.000 rs10220733 chr15:85280864 G/A cg12501888 chr15:85177176 SCAND2 -0.48 -4.49 -0.37 1.6e-5 P wave terminal force; TGCT cis rs1371867 0.726 rs1660333 chr8:101309989 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.72 -0.39 6.15e-6 Atrioventricular conduction; TGCT cis rs12477438 0.765 rs12468807 chr2:99691994 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg17054783 chr10:134559939 INPP5A 0.27 5.24 0.43 6.75e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9300255 0.602 rs1727313 chr12:123640853 C/G cg00376283 chr12:123451042 ABCB9 0.72 4.96 0.41 2.31e-6 Neutrophil percentage of white cells; TGCT cis rs7772486 0.558 rs702322 chr6:146007166 G/A cg05347473 chr6:146136440 FBXO30 -0.65 -6.11 -0.48 1.17e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg23248424 chr5:179741104 GFPT2 0.37 7.04 0.53 1.16e-10 Height; TGCT trans rs66573146 1.000 rs73088528 chr4:6967747 G/C cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs1799949 0.965 rs4239149 chr17:41328095 A/G cg10047753 chr17:41438598 NA -0.74 -7.09 -0.54 8.78e-11 Menopause (age at onset); TGCT cis rs1865760 0.566 rs7772312 chr6:26049616 G/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.98 0.41 2.12e-6 Height; TGCT cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -1.06 -14.78 -0.8 3.86e-29 Menarche (age at onset); TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs7917772 0.503 rs7068535 chr10:104349127 C/T cg05855489 chr10:104503620 C10orf26 -0.61 -5.41 -0.44 3.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9372498 0.505 rs9320655 chr6:118830981 T/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT trans rs57221529 0.766 rs4527146 chr5:555236 A/G cg25482853 chr8:67687455 SGK3 1.2 10.19 0.68 4.33e-18 Lung disease severity in cystic fibrosis; TGCT cis rs12701220 0.690 rs10243973 chr7:1064983 T/C cg07217954 chr7:1067459 C7orf50 -0.47 -4.57 -0.38 1.14e-5 Bronchopulmonary dysplasia; TGCT cis rs6500602 0.627 rs934929 chr16:4587789 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 -0.26 -4.76 -0.39 5.38e-6 Schizophrenia; TGCT cis rs526231 0.926 rs35805 chr5:102673133 G/C cg05225461 chr5:102596755 C5orf30 0.24 4.5 0.37 1.52e-5 Primary biliary cholangitis; TGCT cis rs2046867 0.862 rs11922794 chr3:72813582 G/C cg25664220 chr3:72788482 NA -0.54 -6.81 -0.52 3.77e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs208520 1.000 rs72884033 chr6:66995747 T/C cg07460842 chr6:66804631 NA 0.8 6.98 0.53 1.61e-10 Exhaled nitric oxide output; TGCT cis rs7937682 0.961 rs11601674 chr11:111634354 C/T cg09085632 chr11:111637200 PPP2R1B -1.2 -11.44 -0.72 3.93e-21 Primary sclerosing cholangitis; TGCT cis rs939658 0.805 rs2177056 chr15:79441489 T/C cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs3796352 1.000 rs11713859 chr3:53042080 C/A cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8013055 0.796 rs11628497 chr14:105970789 C/T cg23356831 chr14:105996513 TMEM121 0.4 6.29 0.49 5.05e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs2455799 0.613 rs13080145 chr3:15880060 C/G cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.76e-6 Mean platelet volume; TGCT cis rs2842992 0.750 rs2758354 chr6:160125854 A/G cg11366901 chr6:160182831 ACAT2 1.01 6.75 0.52 5.02e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs7267979 1.000 rs1888999 chr20:25291848 C/T cg03522245 chr20:25566470 NINL 0.6 6.49 0.5 1.87e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9914988 1.000 rs6803 chr17:27187789 C/T cg20469991 chr17:27169893 C17orf63 0.69 5.05 0.41 1.51e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2404602 0.735 rs56246286 chr15:76690731 C/T cg22467129 chr15:76604101 ETFA 0.49 5.06 0.41 1.5e-6 Blood metabolite levels; TGCT cis rs3617 0.591 rs2276823 chr3:52869263 C/A cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.7 0.39 6.91e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2692947 0.550 rs4613327 chr2:96583823 G/A cg13655245 chr2:97463316 CNNM4 0.15 4.51 0.38 1.48e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7949030 0.591 rs35156678 chr11:62369881 G/A cg13298116 chr11:62369859 EML3;MTA2 0.64 9.48 0.65 2.35e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9500256 0.903 rs726783 chr6:58332861 A/C cg16251399 chr6:58287822 GUSBL2 0.66 6.02 0.48 1.82e-8 Eosinophilic esophagitis (pediatric); TGCT cis rs7944584 0.632 rs749067 chr11:47318157 T/C cg20307385 chr11:47447363 PSMC3 0.79 7.89 0.58 1.37e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs6459788 0.720 rs11974772 chr7:157250645 G/A cg06271696 chr7:157225062 NA -0.28 -4.95 -0.41 2.37e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs6964587 0.904 rs6465339 chr7:91570790 T/A cg17063962 chr7:91808500 NA -0.91 -9.71 -0.66 6.35e-17 Breast cancer; TGCT cis rs3784262 1.000 rs7495968 chr15:58244103 C/G cg12031962 chr15:58353849 ALDH1A2 0.49 7.5 0.56 1.08e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2439831 0.867 rs7170489 chr15:43636651 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs10992471 0.603 rs1980848 chr9:95248571 A/G cg14631576 chr9:95140430 CENPP 0.3 4.49 0.37 1.63e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs7914558 1.000 rs7920251 chr10:104950197 C/T cg05855489 chr10:104503620 C10orf26 0.52 4.59 0.38 1.06e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9611565 0.694 rs5758411 chr22:42079734 G/A cg03806693 chr22:41940476 POLR3H 0.97 9.76 0.66 4.74e-17 Vitiligo; TGCT cis rs17331151 0.573 rs2240916 chr3:52859212 T/A cg07884673 chr3:53033167 SFMBT1 0.5 5.97 0.47 2.3e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1801251 1.000 rs6747645 chr2:233571033 C/T cg08000102 chr2:233561755 GIGYF2 -0.64 -6.67 -0.51 7.63e-10 Coronary artery disease; TGCT cis rs7226408 0.948 rs72883588 chr18:34390473 T/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs12220238 1.000 rs7905536 chr10:75997209 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.24 0.55 4.07e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9359856 0.510 rs2748298 chr6:90436877 A/C cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.66 -0.39 7.9e-6 Bipolar disorder; TGCT cis rs34546498 1 rs34546498 chr6:26961280 C/T cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Breast cancer; TGCT cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs1799949 0.965 rs4792989 chr17:41437552 T/C cg23758822 chr17:41437982 NA 0.68 6.37 0.5 3.42e-9 Menopause (age at onset); TGCT cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg06481639 chr22:41940642 POLR3H -0.77 -6.69 -0.51 6.88e-10 Vitiligo; TGCT cis rs208520 0.690 rs12198297 chr6:66714665 G/A cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs9611519 0.566 rs4821981 chr22:41415644 A/C cg13695892 chr22:41940480 POLR3H 0.54 5.1 0.42 1.21e-6 Neuroticism; TGCT cis rs7044106 0.537 rs10739573 chr9:123489818 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 5.55 0.45 1.62e-7 Hip circumference adjusted for BMI; TGCT cis rs10791097 0.694 rs4936123 chr11:130740967 G/A cg12179176 chr11:130786555 SNX19 0.82 9.86 0.66 2.82e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6952808 0.898 rs7799782 chr7:1868039 A/G cg22963979 chr7:1858916 MAD1L1 0.32 5.0 0.41 1.88e-6 Bipolar disorder and schizophrenia; TGCT cis rs614226 0.938 rs12857 chr12:120933946 T/G cg01236616 chr12:121019343 POP5 1.25 13.58 0.77 2.71e-26 Type 1 diabetes nephropathy; TGCT cis rs2292864 0.764 rs3892085 chr17:45340480 A/G cg17233517 chr17:45285328 MYL4 0.37 4.79 0.39 4.76e-6 Left atrial antero-posterior diameter; TGCT trans rs6089829 0.962 rs3899032 chr20:61658542 G/A cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7804356 1.000 rs10486478 chr7:26819465 C/T cg03456212 chr7:26904342 SKAP2 -0.59 -4.44 -0.37 1.93e-5 Type 1 diabetes; TGCT cis rs4665809 0.878 rs892448 chr2:26366205 A/G cg27170947 chr2:26402098 FAM59B -0.4 -4.48 -0.37 1.7e-5 Gut microbiome composition (summer); TGCT trans rs4650994 0.789 rs2761471 chr1:178599348 A/C cg05059571 chr16:84539110 KIAA1609 0.4 7.44 0.56 1.49e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9650657 0.513 rs7005884 chr8:10796472 A/G cg27411982 chr8:10470053 RP1L1 -0.22 -4.55 -0.38 1.26e-5 Neuroticism; TGCT trans rs3780486 0.522 rs1328898 chr9:33163271 A/G cg04842962 chr6:43655489 MRPS18A 0.8 8.67 0.61 2.02e-14 IgG glycosylation; TGCT cis rs11018874 0.808 rs71471032 chr11:89888921 A/T cg05041596 chr11:89867385 NAALAD2 0.54 4.9 0.4 2.97e-6 White blood cell types; TGCT cis rs3008870 1.000 rs2815348 chr1:67472165 G/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs7020830 0.830 rs17487601 chr9:37213641 G/A cg14294708 chr9:37120828 ZCCHC7 1.22 14.18 0.79 1.03e-27 Schizophrenia; TGCT trans rs7618501 0.521 rs11130222 chr3:49901060 A/T cg21659725 chr3:3221576 CRBN 0.69 7.72 0.57 3.29e-12 Intelligence (multi-trait analysis); TGCT cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs7511006 1.000 rs17836662 chr22:50672154 A/G cg16473166 chr22:50639996 SELO -0.62 -6.09 -0.48 1.29e-8 Obesity-related traits; TGCT cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg04317338 chr11:64019027 PLCB3 0.77 6.33 0.49 4e-9 Mean platelet volume; TGCT cis rs7542091 0.669 rs7540534 chr1:210044824 A/T cg00989853 chr1:209979345 IRF6 0.43 4.58 0.38 1.12e-5 Monobrow; TGCT cis rs72781680 0.898 rs72786278 chr2:24063243 C/T cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs9393777 0.720 rs34864993 chr6:26970895 C/A cg16898833 chr6:26189333 HIST1H4D 0.97 5.95 0.47 2.6e-8 Intelligence (multi-trait analysis); TGCT cis rs1729951 0.575 rs16844326 chr3:136678385 G/C cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs902774 0.530 rs12819597 chr12:53353956 T/C cg05393297 chr12:53359155 NA -0.85 -5.44 -0.44 2.73e-7 Prostate cancer; TGCT cis rs2239547 0.603 rs71301807 chr3:53085475 C/G cg10802521 chr3:52805072 NEK4 -0.54 -4.9 -0.4 2.99e-6 Schizophrenia; TGCT cis rs826838 0.935 rs11169511 chr12:39175802 T/C cg26384229 chr12:38710491 ALG10B 1.0 8.98 0.63 3.56e-15 Heart rate; TGCT cis rs3947 0.687 rs1736065 chr8:11685453 A/G cg02840367 chr8:11660030 FDFT1 0.87 6.14 0.48 1e-8 Blood protein levels; TGCT cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs7772486 0.875 rs2814866 chr6:146339414 C/A cg05347473 chr6:146136440 FBXO30 0.5 4.73 0.39 6.03e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9486715 0.867 rs3849199 chr6:97049191 T/C cg18709589 chr6:96969512 KIAA0776 -0.84 -8.23 -0.59 2.19e-13 Headache; TGCT cis rs28595532 0.920 rs116047800 chr4:119773569 G/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs6964587 1.000 rs13231238 chr7:91653851 T/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs9906944 0.707 rs4794020 chr17:47111399 C/T cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs2688608 0.587 rs2894040 chr10:75478159 A/C cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs7226408 0.857 rs17567674 chr18:34480016 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs478304 0.651 rs4930312 chr11:65499719 G/A cg27068330 chr11:65405492 SIPA1 -0.94 -9.4 -0.65 3.49e-16 Acne (severe); TGCT cis rs4919694 1.000 rs75219158 chr10:104747594 C/T cg04362960 chr10:104952993 NT5C2 1.07 7.11 0.54 7.9e-11 Arsenic metabolism; TGCT cis rs13082711 0.522 rs4973760 chr3:27349047 G/A cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7829975 0.536 rs2980439 chr8:8094870 G/A cg06636001 chr8:8085503 FLJ10661 0.89 9.08 0.63 2.07e-15 Mood instability; TGCT cis rs929354 1.000 rs8101 chr7:157061474 A/G cg05182265 chr7:156933206 UBE3C 0.3 6.34 0.5 3.81e-9 Body mass index; TGCT cis rs16854884 0.837 rs13062793 chr3:143808387 A/G cg06585982 chr3:143692056 C3orf58 0.66 5.04 0.41 1.59e-6 Economic and political preferences (feminism/equality); TGCT cis rs6728642 0.572 rs2872686 chr2:97601024 A/G cg26665480 chr2:98280029 ACTR1B -0.9 -6.56 -0.51 1.34e-9 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT trans rs941408 1.000 rs1640272 chr19:2800192 A/T cg22153745 chr1:153894579 GATAD2B -0.64 -7.07 -0.54 9.84e-11 Total cholesterol levels; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 -0.44 -6.37 -0.5 3.32e-9 Lymphocyte counts; TGCT cis rs4975616 0.869 rs31484 chr5:1337906 A/T cg07493874 chr5:1342172 CLPTM1L -0.28 -6.82 -0.52 3.59e-10 Lung cancer; TGCT cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.1 14.26 0.79 6.49e-28 Height; TGCT cis rs2692947 0.683 rs62153700 chr2:96581338 C/T cg22654517 chr2:96458247 NA 0.22 4.57 0.38 1.16e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs524023 0.957 rs12365089 chr11:64364735 A/T cg07733098 chr11:64478343 NRXN2 0.32 4.87 0.4 3.4e-6 Urate levels in obese individuals; TGCT cis rs2721195 0.845 rs1063739 chr8:145729727 C/A cg17328964 chr8:145687451 CYHR1 -0.4 -5.41 -0.44 3.08e-7 Age at first birth; TGCT cis rs7769051 0.522 rs7761207 chr6:133110430 G/A cg07930552 chr6:133119739 C6orf192 1.28 5.03 0.41 1.69e-6 Type 2 diabetes nephropathy; TGCT cis rs6430585 0.527 rs62168836 chr2:136463117 G/A cg07169764 chr2:136633963 MCM6 1.01 9.4 0.64 3.64e-16 Corneal structure; TGCT cis rs7954584 0.567 rs1169071 chr12:122390084 G/T cg13699009 chr12:122356056 WDR66 0.29 5.95 0.47 2.6e-8 Mean corpuscular volume; TGCT trans rs9354352 1.000 rs9354352 chr6:66696272 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.72 7.89 0.58 1.33e-12 Initial pursuit acceleration in psychotic disorders; TGCT cis rs7539409 0.831 rs6576940 chr1:84220236 C/T cg10977910 chr1:84465055 TTLL7 -0.83 -4.62 -0.38 9.6e-6 Alzheimer's disease; TGCT cis rs1371867 0.846 rs1660348 chr8:101315248 A/G cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs7666738 0.791 rs13146909 chr4:98934198 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs709400 0.633 rs10143247 chr14:103920927 G/A cg12935359 chr14:103987150 CKB -0.35 -5.33 -0.43 4.54e-7 Body mass index; TGCT cis rs80282103 0.764 rs12268949 chr10:1104257 A/G cg08668510 chr10:1095578 IDI1 1.01 4.51 0.38 1.48e-5 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs13118892 chr4:98968497 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs13191362 1.000 rs1333963 chr6:163192571 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.77 0.52 4.6e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs1476679 1.000 rs34919929 chr7:100012334 G/A cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.5 -0.37 1.52e-5 Alzheimer's disease (late onset); TGCT cis rs12477438 0.798 rs9808541 chr2:99642179 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT trans rs525455 1.000 rs1761794 chr10:13102815 T/C cg21721093 chr17:8906386 NA 0.63 6.62 0.51 9.7e-10 Platelet aggregation; TGCT cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg05552183 chr6:42928497 GNMT 0.52 4.55 0.38 1.25e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7772486 0.806 rs4243478 chr6:146284560 A/G cg23711669 chr6:146136114 FBXO30 -0.8 -8.72 -0.62 1.51e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs981844 1.000 rs72731669 chr4:154662464 G/A cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs79057730 0.599 rs6951032 chr7:794092 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.8 6.13 0.48 1.06e-8 Initial pursuit acceleration; TGCT cis rs7617480 0.648 rs9859473 chr3:48837182 A/G cg07636037 chr3:49044803 WDR6 0.78 6.47 0.5 2.07e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs6938 0.596 rs11630918 chr15:75155896 C/T cg09165964 chr15:75287851 SCAMP5 0.56 5.1 0.42 1.22e-6 Breast cancer; TGCT cis rs938554 0.513 rs3775947 chr4:9995240 C/T cg00071950 chr4:10020882 SLC2A9 0.57 4.77 0.39 5.07e-6 Blood metabolite levels; TGCT cis rs9393777 0.582 rs6936561 chr6:26640895 C/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.51 -4.68 -0.39 7.36e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs2482931 chr20:25334445 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs208520 0.690 rs207108 chr6:66794096 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT trans rs916888 0.773 rs199457 chr17:44795469 C/T cg22968622 chr17:43663579 NA 1.3 11.58 0.72 1.83e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9811920 0.599 rs61148087 chr3:99539891 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 7.0 0.53 1.44e-10 Axial length; TGCT cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg16145915 chr7:1198662 ZFAND2A -0.56 -7.1 -0.54 8.54e-11 Longevity;Endometriosis; TGCT cis rs9309473 0.687 rs11126399 chr2:73613341 G/A cg20560298 chr2:73613845 ALMS1 -0.48 -5.38 -0.44 3.58e-7 Metabolite levels; TGCT cis rs5769707 0.521 rs5769719 chr22:50062101 G/A cg05373962 chr22:49881684 NA -0.32 -5.47 -0.44 2.43e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6570726 0.935 rs422540 chr6:145837815 G/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg05890377 chr2:74357713 NA 0.5 6.75 0.52 5.16e-10 Gestational age at birth (maternal effect); TGCT cis rs506338 0.517 rs12269736 chr11:64471986 T/C cg19395706 chr11:64412079 NRXN2 0.54 6.47 0.5 2.06e-9 Body mass index;Urate levels; TGCT cis rs2180341 0.781 rs877102 chr6:127587086 T/C cg24812749 chr6:127587940 RNF146 0.79 6.6 0.51 1.09e-9 Breast cancer; TGCT cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs7178572 0.849 rs12901503 chr15:77819056 A/G cg22256960 chr15:77711686 NA -0.97 -11.03 -0.7 3.83e-20 Type 2 diabetes; TGCT cis rs9467773 1.000 rs9986382 chr6:26550619 T/C cg09904177 chr6:26538194 HMGN4 0.65 6.55 0.51 1.36e-9 Intelligence (multi-trait analysis); TGCT cis rs9818758 0.607 rs12715434 chr3:49295025 G/C cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs35306767 0.668 rs12784928 chr10:1083617 A/C cg26597838 chr10:835615 NA 0.47 5.38 0.43 3.58e-7 Eosinophil percentage of granulocytes; TGCT cis rs9397585 0.588 rs9371676 chr6:153445965 C/A cg24028809 chr6:153414101 RGS17 0.22 4.66 0.39 8.15e-6 Body mass index; TGCT trans rs74910095 0.786 rs73117196 chr5:62943718 G/A cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7524258 0.868 rs6693725 chr1:7307810 G/T cg07173049 chr1:7289937 CAMTA1 0.28 4.54 0.38 1.32e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs68170813 0.559 rs75154004 chr7:106903326 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs6840360 0.642 rs10454251 chr4:152383962 A/G cg17479576 chr4:152424074 FAM160A1 -0.59 -6.12 -0.48 1.13e-8 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.659 rs35928756 chr17:56702652 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs2404602 0.583 rs4381566 chr15:76589262 A/G cg22467129 chr15:76604101 ETFA -0.61 -7.93 -0.58 1.07e-12 Blood metabolite levels; TGCT cis rs2230307 0.536 rs526128 chr1:100473427 T/A cg24955406 chr1:100503596 HIAT1 0.75 4.88 0.4 3.2e-6 Carotid intima media thickness; TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg18722847 chr3:44754129 ZNF502 -0.4 -4.47 -0.37 1.75e-5 Depressive symptoms; TGCT cis rs8038465 0.874 rs2291013 chr15:74000506 T/G cg15420318 chr15:73925796 NPTN 0.57 5.15 0.42 1.02e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1371867 0.846 rs1660351 chr8:101275034 C/T cg06002616 chr8:101225028 SPAG1 -0.57 -6.77 -0.52 4.48e-10 Atrioventricular conduction; TGCT cis rs9650657 0.801 rs7018334 chr8:10612075 G/A cg16664915 chr8:10907788 XKR6 -0.3 -4.76 -0.39 5.38e-6 Neuroticism; TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg08859206 chr1:53392774 SCP2 -0.41 -6.12 -0.48 1.11e-8 Monocyte count; TGCT cis rs11031096 0.655 rs10835695 chr11:4178962 G/T cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7193541 0.550 rs28607667 chr16:74476015 C/T cg05800356 chr16:74706258 MLKL -0.23 -4.5 -0.37 1.53e-5 Multiple myeloma; TGCT cis rs1488864 0.614 rs1552516 chr11:6351787 A/T cg12755421 chr11:6342214 PRKCDBP -0.6 -4.51 -0.38 1.47e-5 Smooth-surface caries; TGCT cis rs10875746 0.855 rs17122620 chr12:48464475 A/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs12134245 0.742 rs17501381 chr1:92003919 A/G cg07090678 chr1:91966139 CDC7 0.35 4.75 0.39 5.58e-6 Breast cancer; TGCT cis rs62380364 0.565 rs13158247 chr5:88030670 C/T cg24804195 chr5:87968844 LOC645323 -0.61 -6.27 -0.49 5.52e-9 Intelligence (multi-trait analysis); TGCT cis rs908922 0.651 rs4240885 chr1:152529850 G/C cg20991723 chr1:152506922 NA 0.44 5.98 0.47 2.2e-8 Hair morphology; TGCT cis rs12620999 1.000 rs10803655 chr2:238075551 C/T cg23555395 chr2:238036564 NA -0.28 -4.8 -0.4 4.49e-6 Systemic lupus erythematosus; TGCT cis rs394563 0.726 rs6942381 chr6:149662991 G/C cg16235748 chr6:149772707 ZC3H12D 0.47 5.53 0.44 1.84e-7 Dupuytren's disease; TGCT cis rs60154123 0.730 rs10779528 chr1:210457378 C/T cg22029157 chr1:209979665 IRF6 0.6 4.46 0.37 1.81e-5 Coronary artery disease; TGCT cis rs7208859 0.623 rs55961983 chr17:29119286 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9394169 0.875 rs1547670 chr6:33775868 G/A cg13859433 chr6:33739653 LEMD2 -0.33 -5.85 -0.47 4.02e-8 Essential tremor; TGCT cis rs9467773 1.000 rs9467791 chr6:26562486 A/G cg26531700 chr6:26746687 NA -0.46 -4.5 -0.37 1.55e-5 Intelligence (multi-trait analysis); TGCT cis rs7000551 0.527 rs12677619 chr8:22243326 G/A cg12081754 chr8:22256438 SLC39A14 0.32 4.58 0.38 1.09e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs28595532 0.920 rs116550416 chr4:119753467 A/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2688608 0.592 rs10762560 chr10:75495405 T/G cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs12477438 0.798 rs6740267 chr2:99561867 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.83 -8.07 -0.59 5.19e-13 Chronic sinus infection; TGCT cis rs7572733 0.555 rs10202569 chr2:198934726 C/G cg00792783 chr2:198669748 PLCL1 0.58 5.16 0.42 9.47e-7 Dermatomyositis; TGCT cis rs4733781 0.787 rs6470812 chr8:131340265 G/A cg16277922 chr8:131349729 ASAP1 -0.36 -4.63 -0.38 9.06e-6 Tuberculosis; TGCT cis rs9883204 0.817 rs35606005 chr3:123129170 C/T cg04890266 chr3:123102914 ADCY5 0.36 5.08 0.42 1.34e-6 Birth weight; TGCT cis rs80282103 0.618 rs11816485 chr10:1147974 T/C cg08668510 chr10:1095578 IDI1 1.05 5.31 0.43 4.8e-7 Glomerular filtration rate (creatinine); TGCT cis rs12220898 0.749 rs4497321 chr10:50475018 C/T cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.85e-5 Inflammatory biomarkers; TGCT trans rs1005277 0.579 rs2472182 chr10:38388865 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs11711311 0.955 rs12636240 chr3:113391282 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.8 -6.99 -0.53 1.48e-10 IgG glycosylation; TGCT cis rs7100689 0.784 rs3802637 chr10:82179699 G/C cg01528321 chr10:82214614 TSPAN14 0.9 9.37 0.64 4.33e-16 Post bronchodilator FEV1; TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg06873352 chr17:61820015 STRADA 0.56 6.23 0.49 6.49e-9 Prudent dietary pattern; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg18538332 chr22:24372958 LOC391322 -1.01 -12.84 -0.76 1.6e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg02073558 chr3:44770973 ZNF501 0.67 6.68 0.51 7.31e-10 Depressive symptoms; TGCT cis rs644799 0.542 rs10831418 chr11:95468828 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.67 6.5 0.5 1.76e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs1415174 0.916 rs746191 chr1:87849215 A/G cg23065576 chr20:25207247 ENTPD6 -0.26 -6.91 -0.53 2.29e-10 Breast cancer; TGCT cis rs739401 0.611 rs7109088 chr11:3027485 G/T cg05729581 chr11:3078854 CARS -0.53 -4.81 -0.4 4.3e-6 Longevity; TGCT cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs477895 0.838 rs12798333 chr11:64012784 G/A cg04317338 chr11:64019027 PLCB3 0.81 6.9 0.53 2.35e-10 Mean platelet volume; TGCT trans rs9650657 0.572 rs11250098 chr8:10818607 A/G cg15556689 chr8:8085844 FLJ10661 -0.95 -10.05 -0.67 9.79e-18 Neuroticism; TGCT cis rs10791097 0.694 rs4937581 chr11:130740335 T/C cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1903068 0.785 rs28584303 chr4:55997622 C/T cg01777861 chr4:56023843 NA 0.55 6.37 0.5 3.34e-9 Endometriosis; TGCT cis rs11098499 0.954 rs2892848 chr4:120381341 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs4889855 0.530 rs75398920 chr17:78544540 C/T cg16591659 chr17:78472290 NA 0.29 4.47 0.37 1.76e-5 Fractional excretion of uric acid; TGCT cis rs13202913 0.518 rs13205543 chr6:151813779 C/T cg03627880 chr6:151815985 C6orf97 -0.66 -6.01 -0.47 1.95e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs4888262 0.545 rs7342732 chr16:74698716 A/C cg01733217 chr16:74700730 RFWD3 0.75 7.65 0.57 4.96e-12 Testicular germ cell tumor; TGCT trans rs7615952 0.932 rs6438948 chr3:125650045 A/T cg07211511 chr3:129823064 LOC729375 0.43 7.48 0.56 1.18e-11 Blood pressure (smoking interaction); TGCT cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs7944584 0.837 rs11039149 chr11:47276675 A/G cg20307385 chr11:47447363 PSMC3 0.77 7.16 0.54 6.19e-11 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs55971108 0.653 rs12284518 chr11:134876086 C/T cg21104351 chr11:134152202 GLB1L3 0.48 4.46 0.37 1.82e-5 Alcoholic chronic pancreatitis; TGCT cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg04317338 chr11:64019027 PLCB3 0.78 6.46 0.5 2.17e-9 Mean platelet volume; TGCT cis rs813218 0.647 rs6788750 chr3:99774720 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.48 -5.7 -0.46 8.42e-8 Orofacial clefts; TGCT cis rs11098499 0.909 rs10026736 chr4:120384322 G/C cg09307838 chr4:120376055 NA 0.67 6.38 0.5 3.14e-9 Corneal astigmatism; TGCT cis rs2204008 0.775 rs12099736 chr12:38344111 C/G cg13010199 chr12:38710504 ALG10B 0.59 4.63 0.38 9.17e-6 Bladder cancer; TGCT cis rs9972944 0.756 rs9901885 chr17:63769559 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs3862260 0.509 rs10802124 chr1:120164252 G/A cg16322792 chr1:120165303 ZNF697 0.35 8.4 0.6 8.92e-14 Systemic lupus erythematosus; TGCT cis rs57994353 0.861 rs3812591 chr9:139341612 C/T cg13741927 chr9:139327495 INPP5E 0.25 5.76 0.46 6.12e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9372498 0.536 rs9489450 chr6:118904385 G/A cg07617317 chr6:118971624 C6orf204 0.5 5.32 0.43 4.71e-7 Diastolic blood pressure; TGCT cis rs2535633 0.820 rs7626551 chr3:52938092 C/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.65 -0.39 8.52e-6 Body mass index; TGCT cis rs2288278 0.580 rs10853099 chr17:46602379 T/C cg25032089 chr17:46643351 HOXB3 -0.42 -5.0 -0.41 1.89e-6 Hand grip strength; TGCT cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6460942 0.915 rs62447640 chr7:12488282 A/T cg06484146 chr7:12443880 VWDE -0.61 -5.43 -0.44 2.87e-7 Coronary artery disease; TGCT cis rs9394841 0.667 rs9367112 chr6:41769920 T/C cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs7681440 0.804 rs1442135 chr4:90819093 C/T cg20003494 chr4:90757398 SNCA 0.59 5.97 0.47 2.29e-8 Dementia with Lewy bodies; TGCT cis rs4555082 0.834 rs2816631 chr14:105739477 G/A cg01266790 chr14:105781312 PACS2 0.56 4.6 0.38 1.04e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs6121246 0.529 rs6058196 chr20:30194714 A/T cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs8072100 0.905 rs9901869 chr17:45575206 G/A cg08085267 chr17:45401833 C17orf57 -0.44 -4.72 -0.39 6.17e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1997103 0.871 rs1997100 chr7:55399656 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs694739 0.536 rs671976 chr11:64046029 G/A cg23796481 chr11:64053134 BAD;GPR137 0.55 5.33 0.43 4.5e-7 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs9346649 1.000 rs9346649 chr6:168490232 A/G cg02770688 chr6:168491649 NA -0.27 -5.23 -0.42 7.09e-7 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs72949976 0.646 rs1441171 chr2:214033637 G/T cg08319019 chr2:214017104 IKZF2 0.85 8.35 0.6 1.17e-13 Lung cancer;Squamous cell lung carcinoma; TGCT trans rs11764590 0.671 rs56226325 chr7:2078981 C/T cg25206134 chr2:45395956 NA 0.97 6.73 0.52 5.68e-10 Neuroticism; TGCT cis rs4654899 0.897 rs7515308 chr1:21085653 G/C cg01072550 chr1:21505969 NA -0.49 -7.89 -0.58 1.37e-12 Superior frontal gyrus grey matter volume; TGCT cis rs4389656 0.784 rs274723 chr5:6718563 A/G cg10857441 chr5:6722123 POLS -0.22 -4.86 -0.4 3.44e-6 Coronary artery disease; TGCT cis rs9486719 1.000 rs13207333 chr6:96882254 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs796364 1.000 rs281763 chr2:200794870 C/T cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs2228479 0.717 rs1800358 chr16:89809319 T/C cg04287289 chr16:89883240 FANCA 0.74 4.44 0.37 1.99e-5 Skin colour saturation; TGCT cis rs11105298 0.891 rs10858879 chr12:89886578 A/T cg00757033 chr12:89920650 WDR51B -0.34 -5.37 -0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs425277 0.520 rs10910030 chr1:2035684 C/T cg03732007 chr1:2071316 PRKCZ -0.28 -6.06 -0.48 1.51e-8 Height; TGCT cis rs4737010 0.501 rs2032736 chr8:41639266 C/A cg07235638 chr8:41625417 ANK1 -0.49 -4.66 -0.39 7.96e-6 Lymphocyte counts;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular volume;Immature fraction of reticulocytes;Mean corpuscular hemoglobin concentration; TGCT cis rs13191362 0.507 rs2846519 chr6:163045463 G/A cg21926612 chr6:163149169 PACRG;PARK2 -0.61 -5.78 -0.46 5.77e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12681287 0.752 rs10086569 chr8:87247209 C/T cg27223183 chr8:87520930 FAM82B -0.81 -5.7 -0.46 8.13e-8 Caudate activity during reward; TGCT cis rs8103278 0.507 rs7246377 chr19:46292259 G/A cg11657440 chr19:46296263 DMWD 0.76 8.25 0.6 1.93e-13 Coronary artery disease; TGCT cis rs9583531 0.600 rs6492303 chr13:111356800 G/A cg24331049 chr13:111365604 ING1 0.77 7.44 0.56 1.45e-11 Coronary artery disease; TGCT cis rs1865760 0.713 rs9461229 chr6:25992279 G/T cg17042849 chr6:26104293 HIST1H4C -0.55 -4.8 -0.4 4.4e-6 Height; TGCT cis rs7833790 1.000 rs7834808 chr8:82704996 A/G cg17211192 chr8:82754475 SNX16 -1.11 -8.7 -0.62 1.72e-14 Diastolic blood pressure; TGCT cis rs9942416 0.660 rs2047059 chr5:75008193 T/C cg19683494 chr5:74908142 NA 0.6 6.16 0.48 9.25e-9 Age-related disease endophenotypes; TGCT cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg01411255 chr17:61851458 DDX42;CCDC47 -1.04 -12.35 -0.74 2.39e-23 Height; TGCT cis rs4888262 0.526 rs8062959 chr16:74627628 T/C cg01733217 chr16:74700730 RFWD3 0.74 7.42 0.55 1.6e-11 Testicular germ cell tumor; TGCT cis rs10791323 0.598 rs10750550 chr11:133736083 A/G cg03690763 chr11:133734501 NA -0.29 -4.86 -0.4 3.54e-6 Childhood ear infection; TGCT cis rs1519814 0.654 rs6469888 chr8:121018175 A/G cg22335954 chr8:121166405 COL14A1 -0.38 -4.76 -0.39 5.35e-6 Breast cancer; TGCT cis rs6430585 0.591 rs12466487 chr2:136407078 C/T cg07169764 chr2:136633963 MCM6 -1.06 -8.97 -0.63 3.94e-15 Corneal structure; TGCT cis rs155076 1.000 rs261432 chr13:21865915 G/C cg14456004 chr13:21872349 NA -1.18 -10.17 -0.67 5e-18 White matter hyperintensity burden; TGCT cis rs732765 0.734 rs3784021 chr14:75200653 C/T cg06637938 chr14:75390232 RPS6KL1 -0.55 -4.48 -0.37 1.71e-5 Non-small cell lung cancer; TGCT cis rs4332037 0.539 rs1533827 chr7:2074290 A/G cg24505167 chr7:1915268 MAD1L1 0.3 4.5 0.37 1.52e-5 Bipolar disorder; TGCT cis rs137699 1.000 rs2049986 chr22:39756854 C/G cg24399712 chr22:39784796 NA 0.67 6.35 0.5 3.72e-9 IgG glycosylation; TGCT cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg25151919 chr3:44754333 ZNF502 -0.39 -4.6 -0.38 1.02e-5 Depressive symptoms; TGCT cis rs12477438 0.798 rs4851179 chr2:99568774 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.9 -9.1 -0.63 1.84e-15 Chronic sinus infection; TGCT cis rs2235642 0.750 rs2755185 chr16:1645827 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.57 -0.38 1.17e-5 Coronary artery disease; TGCT cis rs3749237 0.929 rs62260715 chr3:49829326 G/A cg03060546 chr3:49711283 APEH 0.73 7.58 0.56 7.07e-12 Resting heart rate; TGCT cis rs9486719 1.000 rs2472889 chr6:96866803 T/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7586879 0.639 rs2384058 chr2:25100328 A/G cg15423357 chr2:25149977 NA 0.49 4.76 0.39 5.32e-6 Body mass index; TGCT cis rs875971 0.522 rs10807697 chr7:65416170 A/G cg00343986 chr7:65444356 GUSB 0.26 6.07 0.48 1.42e-8 Aortic root size; TGCT cis rs597539 0.652 rs514833 chr11:68657734 C/T cg21963583 chr11:68658836 MRPL21 0.36 6.08 0.48 1.35e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10186029 0.648 rs13022006 chr2:213940309 A/C cg08319019 chr2:214017104 IKZF2 0.63 5.94 0.47 2.67e-8 Systemic sclerosis; TGCT cis rs28595532 0.920 rs17325129 chr4:119778284 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs7193541 0.646 rs4888267 chr16:74687906 A/G cg01733217 chr16:74700730 RFWD3 1.0 13.51 0.77 3.95e-26 Multiple myeloma; TGCT cis rs9467711 0.591 rs13216785 chr6:26079185 C/T cg16898833 chr6:26189333 HIST1H4D 0.78 4.45 0.37 1.87e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg17264618 chr3:40429014 ENTPD3 -0.33 -4.78 -0.39 4.92e-6 Renal cell carcinoma; TGCT cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg07424592 chr7:64974309 NA 1.25 8.03 0.58 6.38e-13 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs958550 chr7:65635679 C/T cg07424592 chr7:64974309 NA -1.29 -7.96 -0.58 9.33e-13 Diabetic kidney disease; TGCT cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg13342137 chr4:2252803 MXD4 0.17 4.58 0.38 1.09e-5 Obesity-related traits; TGCT cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.91 7.28 0.55 3.32e-11 Platelet count; TGCT cis rs7937682 0.924 rs10891288 chr11:111552053 G/T cg09085632 chr11:111637200 PPP2R1B 1.08 11.72 0.73 8.02e-22 Primary sclerosing cholangitis; TGCT trans rs11764590 0.715 rs56289396 chr7:2091415 G/A cg25206134 chr2:45395956 NA 0.97 6.72 0.52 5.86e-10 Neuroticism; TGCT cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg23758822 chr17:41437982 NA 0.71 6.64 0.51 8.91e-10 Menopause (age at onset); TGCT cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg13409248 chr3:40428643 ENTPD3 0.65 5.29 0.43 5.25e-7 Renal cell carcinoma; TGCT cis rs12908161 0.920 rs12904605 chr15:85201419 T/C cg11189052 chr15:85197271 WDR73 0.74 6.09 0.48 1.3e-8 Schizophrenia; TGCT cis rs2439831 1.000 rs2444032 chr15:43755346 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.99 7.96 0.58 9.41e-13 Lung cancer in ever smokers; TGCT cis rs1348850 0.914 rs7565022 chr2:178320222 A/T cg22681709 chr2:178499509 PDE11A -0.34 -4.47 -0.37 1.72e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4389656 0.857 rs274709 chr5:6726464 T/C cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs7412746 0.658 rs2089082 chr1:150800090 T/G cg09365446 chr1:150670422 GOLPH3L 0.35 5.13 0.42 1.1e-6 Melanoma; TGCT trans rs916888 0.773 rs199533 chr17:44828931 G/A cg22433210 chr17:43662623 NA 1.05 7.46 0.56 1.3e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg24675658 chr1:53192096 ZYG11B 0.69 8.05 0.59 5.8e-13 Monocyte count; TGCT cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg04944784 chr2:26401820 FAM59B -0.76 -6.45 -0.5 2.29e-9 Gut microbiome composition (summer); TGCT cis rs2282802 0.685 rs1529693 chr5:139678213 A/G cg01081189 chr5:139537190 NA 0.29 5.31 0.43 5e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.906 rs7846666 chr8:58172302 T/C cg22535103 chr8:58192502 C8orf71 -0.37 -4.73 -0.39 6.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs7172809 0.574 rs74026913 chr15:77733083 A/G cg22256960 chr15:77711686 NA -0.51 -4.87 -0.4 3.32e-6 Glucose homeostasis traits; TGCT cis rs7208859 0.673 rs9899943 chr17:29223925 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs74233809 1.000 rs11191551 chr10:104850835 A/G cg05855489 chr10:104503620 C10orf26 0.79 4.56 0.38 1.19e-5 Birth weight; TGCT cis rs11577318 0.853 rs11803933 chr1:26629465 G/C cg12733254 chr1:26682999 NA -0.2 -4.45 -0.37 1.89e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs11122272 0.735 rs2749723 chr1:231493302 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.73 -7.08 -0.54 9.65e-11 Hemoglobin concentration; TGCT cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg11644478 chr21:40555479 PSMG1 -0.87 -7.93 -0.58 1.09e-12 Cognitive function; TGCT cis rs10782582 0.593 rs11579752 chr1:76178694 C/T cg22875332 chr1:76189707 ACADM -0.52 -6.04 -0.48 1.69e-8 Daytime sleep phenotypes; TGCT cis rs67478160 0.634 rs1955660 chr14:104229985 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.38 -0.5 3.18e-9 Schizophrenia; TGCT cis rs6087990 0.701 rs1997797 chr20:31387954 C/G cg13636640 chr20:31349939 DNMT3B 0.97 12.84 0.76 1.63e-24 Ulcerative colitis; TGCT cis rs1865760 0.566 rs9348706 chr6:26065481 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.79 7.55 0.56 8.02e-12 Height; TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT trans rs7618501 1.000 rs11130218 chr3:49752372 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs9581857 0.579 rs9581846 chr13:27987953 A/G cg22138327 chr13:27999177 GTF3A 0.73 5.34 0.43 4.23e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6604026 0.630 rs35807969 chr1:93459069 T/A cg17283838 chr1:93427260 FAM69A 0.57 4.64 0.38 8.79e-6 Multiple sclerosis; TGCT cis rs854765 0.547 rs9894138 chr17:17964345 G/A cg04398451 chr17:18023971 MYO15A 0.31 4.97 0.41 2.18e-6 Total body bone mineral density; TGCT cis rs1023500 0.505 rs134885 chr22:42673811 C/G cg15557168 chr22:42548783 NA -0.21 -4.99 -0.41 2.03e-6 Schizophrenia; TGCT cis rs6952808 0.692 rs6950627 chr7:2086672 C/T cg22963979 chr7:1858916 MAD1L1 -0.37 -5.8 -0.46 5.31e-8 Bipolar disorder and schizophrenia; TGCT cis rs9926296 0.605 rs12599180 chr16:89839306 C/T cg26513180 chr16:89883248 FANCA -0.99 -13.33 -0.77 1.03e-25 Vitiligo; TGCT cis rs10484885 0.878 rs72921934 chr6:90579464 T/A cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9611565 0.559 rs13056262 chr22:42081921 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Vitiligo; TGCT cis rs10193935 0.901 rs1390609 chr2:42666230 G/T cg27598129 chr2:42591480 NA 0.33 4.81 0.4 4.32e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs68170813 0.641 rs75254991 chr7:106938903 C/T cg02696742 chr7:106810147 HBP1 -0.71 -5.93 -0.47 2.88e-8 Coronary artery disease; TGCT cis rs13108904 0.518 rs4974602 chr4:1342391 C/T cg00684032 chr4:1343700 KIAA1530 0.24 5.01 0.41 1.83e-6 Obesity-related traits; TGCT cis rs7666738 0.716 rs6817529 chr4:99023213 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.791 rs62318907 chr4:99037120 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2239547 0.563 rs9876403 chr3:52916916 C/T cg11645453 chr3:52864694 ITIH4 0.33 5.7 0.46 8.39e-8 Schizophrenia; TGCT cis rs7698623 0.850 rs4693883 chr4:88770174 A/G cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs17473412 0.963 rs7731697 chr5:122735452 A/T cg15125798 chr5:122621645 NA -0.55 -4.86 -0.4 3.5e-6 Total body bone mineral density; TGCT cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg02487422 chr3:49467188 NICN1 0.52 5.75 0.46 6.52e-8 Parkinson's disease; TGCT trans rs7698623 0.850 rs7684659 chr4:88769571 G/A cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs7772486 0.806 rs4075696 chr6:146250947 T/C cg23711669 chr6:146136114 FBXO30 -0.8 -8.9 -0.62 5.72e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs151997 0.962 rs27268 chr5:50184778 T/C cg06027927 chr5:50259733 NA 0.47 4.83 0.4 4e-6 Callous-unemotional behaviour; TGCT cis rs17387100 0.901 rs73230225 chr4:15983944 C/T cg14577840 chr4:16257979 FLJ39653 0.48 4.7 0.39 6.69e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs9910055 0.529 rs228766 chr17:42186813 A/G cg13607699 chr17:42295918 UBTF -0.62 -5.01 -0.41 1.85e-6 Total body bone mineral density; TGCT cis rs8068544 0.818 rs8079958 chr17:40155467 C/T cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.09 -5.37 -0.43 3.82e-7 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs3733585 0.673 rs4495037 chr4:9954050 C/G cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9916302 0.904 rs11078897 chr17:37415870 C/T cg07936489 chr17:37558343 FBXL20 -0.63 -4.99 -0.41 2.03e-6 Glomerular filtration rate (creatinine); TGCT cis rs4372836 0.893 rs745645 chr2:28931571 G/T cg09522027 chr2:28974177 PPP1CB 0.57 4.76 0.39 5.24e-6 Body mass index; TGCT cis rs10262624 0.528 rs5029444 chr7:23737795 T/C cg09690326 chr7:23720549 C7orf46 0.43 4.65 0.39 8.21e-6 Schizophrenia; TGCT cis rs3749237 1.000 rs2291542 chr3:49751585 C/T cg03060546 chr3:49711283 APEH 0.75 7.46 0.56 1.33e-11 Resting heart rate; TGCT cis rs7647973 0.731 rs7617480 chr3:49210732 G/T cg07636037 chr3:49044803 WDR6 -0.66 -4.81 -0.4 4.26e-6 Menarche (age at onset); TGCT cis rs589249 0.963 rs761718 chr1:37161263 A/G cg04012535 chr1:37176647 NA -0.31 -5.1 -0.42 1.25e-6 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs6032067 0.673 rs4522674 chr20:43893276 T/C cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -6.37 -0.5 3.36e-9 Blood protein levels; TGCT cis rs2688608 0.592 rs7908825 chr10:75554541 C/G cg23231163 chr10:75533350 FUT11 0.28 4.68 0.39 7.32e-6 Inflammatory bowel disease; TGCT cis rs617219 0.726 rs7717669 chr5:78452983 A/C cg23987322 chr5:78407566 BHMT 0.36 4.82 0.4 4.19e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2204008 0.805 rs11180825 chr12:38242916 G/T cg26384229 chr12:38710491 ALG10B 0.86 7.42 0.55 1.6e-11 Bladder cancer; TGCT cis rs2576037 0.583 rs8086286 chr18:44467515 A/G cg24750912 chr18:44543259 TCEB3CL;KATNAL2 -0.32 -4.75 -0.39 5.59e-6 Personality dimensions; TGCT cis rs362272 0.545 rs2748447 chr4:3337831 G/A cg18352616 chr4:3374830 RGS12 0.22 4.44 0.37 1.93e-5 Serum sulfate level; TGCT cis rs17030434 0.813 rs11732480 chr4:154665733 C/A cg14289246 chr4:154710475 SFRP2 -0.89 -7.26 -0.55 3.75e-11 Electrocardiographic conduction measures; TGCT cis rs2692947 0.795 rs2252697 chr2:96778190 G/C cg22654517 chr2:96458247 NA -0.22 -4.86 -0.4 3.44e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6088580 0.567 rs6088520 chr20:33132364 A/G cg06115741 chr20:33292138 TP53INP2 -0.51 -4.49 -0.37 1.58e-5 Glomerular filtration rate (creatinine); TGCT trans rs1864729 0.748 rs973756 chr8:98297422 G/T cg08679828 chr8:102218111 ZNF706 -1.03 -6.8 -0.52 3.9e-10 Estradiol plasma levels (breast cancer); TGCT cis rs931127 0.719 rs2170082 chr11:65454795 A/G cg27068330 chr11:65405492 SIPA1 -0.63 -6.28 -0.49 5.15e-9 Systemic lupus erythematosus; TGCT cis rs2594989 0.790 rs2443712 chr3:11538063 A/G cg00170343 chr3:11313890 ATG7 0.68 5.2 0.42 8.04e-7 Circulating chemerin levels; TGCT cis rs367943 1.000 rs348930 chr5:112814763 T/C cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs3770081 1.000 rs12622009 chr2:86248325 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -1.18 -4.81 -0.4 4.33e-6 Facial emotion recognition (sad faces); TGCT cis rs7119 0.634 rs11635634 chr15:77863412 T/C cg27398640 chr15:77910606 LINGO1 0.26 4.73 0.39 6.12e-6 Type 2 diabetes; TGCT cis rs6570726 0.577 rs406868 chr6:145809983 C/T cg23711669 chr6:146136114 FBXO30 0.71 6.52 0.51 1.62e-9 Lobe attachment (rater-scored or self-reported); TGCT trans rs1864729 1.000 rs2053481 chr8:98278923 C/T cg08679828 chr8:102218111 ZNF706 -1.1 -7.71 -0.57 3.56e-12 Estradiol plasma levels (breast cancer); TGCT cis rs17376456 0.825 rs10064368 chr5:93266396 C/A cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs7829975 0.533 rs7820146 chr8:8699757 T/A cg15556689 chr8:8085844 FLJ10661 0.66 5.8 0.46 5.2e-8 Mood instability; TGCT cis rs7246657 0.943 rs1382357 chr19:37977609 G/A cg18154014 chr19:37997991 ZNF793 0.7 4.78 0.39 4.87e-6 Coronary artery calcification; TGCT cis rs6912958 0.559 rs242287 chr6:88071825 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.66 6.41 0.5 2.7e-9 Monocyte percentage of white cells; TGCT cis rs2251381 0.808 rs7364112 chr21:30548968 C/A cg24692254 chr21:30365293 RNF160 0.74 7.33 0.55 2.63e-11 Selective IgA deficiency; TGCT cis rs4654899 1.000 rs12126133 chr1:21456537 T/C cg01072550 chr1:21505969 NA -0.5 -8.07 -0.59 5.13e-13 Superior frontal gyrus grey matter volume; TGCT cis rs7091068 0.567 rs1572773 chr10:95432968 T/C cg20715218 chr10:95462985 C10orf4 0.52 5.56 0.45 1.59e-7 Urinary tract infection frequency; TGCT cis rs7772486 0.754 rs1415746 chr6:146077107 A/G cg13319975 chr6:146136371 FBXO30 0.54 4.88 0.4 3.19e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs56399783 0.901 rs17132741 chr7:2868997 C/T cg19731401 chr7:2775893 GNA12 -0.32 -4.73 -0.39 5.93e-6 Childhood ear infection; TGCT cis rs11971779 0.793 rs11543827 chr7:139032693 G/A cg07862535 chr7:139043722 LUC7L2 0.76 6.17 0.48 8.86e-9 Diisocyanate-induced asthma; TGCT cis rs12220898 0.749 rs7905866 chr10:50483552 T/C cg09603381 chr10:49954066 WDFY4 0.39 4.5 0.37 1.54e-5 Inflammatory biomarkers; TGCT cis rs2637266 1.000 rs2579746 chr10:78327674 C/T cg18941641 chr10:78392320 NA 0.41 5.02 0.41 1.74e-6 Pulmonary function; TGCT cis rs28785552 0.589 rs7257371 chr19:53243910 A/G cg10871876 chr19:53194124 ZNF83 0.46 5.91 0.47 3.08e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7937612 1.000 rs6589811 chr11:120235703 C/T cg24566217 chr11:120254723 ARHGEF12 -0.3 -4.81 -0.4 4.21e-6 Intraocular pressure; TGCT cis rs9435341 0.728 rs1762486 chr1:107627697 G/A cg09367891 chr1:107599246 PRMT6 -0.58 -4.74 -0.39 5.74e-6 Facial morphology (factor 21, depth of nasal alae); TGCT trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg18110333 chr6:292329 DUSP22 -0.61 -6.63 -0.51 9.1e-10 Menopause (age at onset); TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg25767906 chr1:53392781 SCP2 -0.5 -6.0 -0.47 2e-8 Monocyte count; TGCT cis rs986417 1.000 rs4901985 chr14:60948318 A/C cg27398547 chr14:60952738 C14orf39 1.35 10.21 0.68 3.99e-18 Gut microbiota (bacterial taxa); TGCT cis rs12142240 0.698 rs72677587 chr1:46813982 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs561341 0.739 rs6505267 chr17:30225950 A/C cg13647721 chr17:30228624 UTP6 0.62 4.93 0.4 2.6e-6 Hip circumference adjusted for BMI; TGCT cis rs7043114 0.525 rs7047089 chr9:95117980 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.56 -0.45 1.61e-7 Height; TGCT cis rs921968 0.541 rs6717433 chr2:219375711 G/C cg02176678 chr2:219576539 TTLL4 -0.48 -6.84 -0.52 3.21e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs12049351 0.665 rs10449251 chr1:229640911 A/G cg12130225 chr1:229698885 NA -0.39 -4.59 -0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs6429082 0.783 rs390539 chr1:235679690 A/C cg26050004 chr1:235667680 B3GALNT2 0.6 5.38 0.43 3.65e-7 Adiposity; TGCT cis rs4246949 0.681 rs10902810 chr10:125521877 G/C cg12769705 chr10:125521557 CPXM2 -0.43 -4.82 -0.4 4.09e-6 Ulcerative colitis; TGCT cis rs2239547 0.563 rs9839035 chr3:52909877 C/T cg10802521 chr3:52805072 NEK4 -0.58 -5.46 -0.44 2.53e-7 Schizophrenia; TGCT cis rs7091068 0.522 rs11187621 chr10:95483074 T/C cg20715218 chr10:95462985 C10orf4 0.5 4.86 0.4 3.49e-6 Urinary tract infection frequency; TGCT cis rs11190604 1.000 rs7477246 chr10:102261538 C/T cg23241863 chr10:102295624 HIF1AN 0.67 5.13 0.42 1.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg15659132 chr6:26577336 NA -0.84 -10.66 -0.69 3.09e-19 Intelligence (multi-trait analysis); TGCT cis rs3809566 0.654 rs4775606 chr15:63327605 A/G cg00520135 chr15:63333846 TPM1 -0.43 -5.35 -0.43 4.07e-7 Platelet count; TGCT cis rs1012621 0.715 rs214809 chr20:2295066 C/G cg20323491 chr20:3218393 SLC4A11 0.33 4.47 0.37 1.73e-5 Inflammatory skin disease; TGCT cis rs184907858 1 rs184907858 chr11:47211786 A/G cg13308137 chr11:47528955 CUGBP1 0.38 4.48 0.37 1.65e-5 Total body bone mineral density; TGCT cis rs7178572 1.000 rs965480 chr15:77781926 A/G cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs9303401 0.614 rs56284918 chr17:57178838 A/G cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs61867294 0.553 rs1404787 chr10:106727681 A/G cg08000847 chr10:105880925 C10orf78 0.48 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs4720575 1.000 rs1074575 chr7:47090545 A/C cg00036614 chr7:47093842 NA -0.22 -5.48 -0.44 2.23e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs6430585 0.528 rs115553816 chr2:136692893 G/A cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs7666738 0.791 rs10017624 chr4:98984009 G/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.791 rs11097601 chr4:98960103 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg11410718 chr7:27170412 HOXA4 -0.47 -4.52 -0.38 1.42e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg21280719 chr6:42927975 GNMT -0.37 -4.54 -0.38 1.32e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1008375 0.900 rs10019460 chr4:17686337 T/C cg18681998 chr4:17616180 MED28 -0.87 -8.73 -0.62 1.45e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs709400 0.633 rs7160208 chr14:103965528 G/A cg12935359 chr14:103987150 CKB -0.36 -5.64 -0.45 1.11e-7 Body mass index; TGCT cis rs11671005 0.735 rs11670871 chr19:58940514 C/T cg13877915 chr19:58951672 ZNF132 -0.63 -4.97 -0.41 2.14e-6 Mean platelet volume; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg19626725 chr5:178986131 RUFY1 0.55 7.64 0.57 5.16e-12 Lung cancer; TGCT cis rs2013441 1.000 rs4924809 chr17:20044673 C/T cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs3748682 0.821 rs12751325 chr1:38289383 T/C cg04496824 chr1:38276835 MTF1 0.21 4.55 0.38 1.26e-5 Hypothyroidism; TGCT cis rs6921919 0.583 rs6922374 chr6:28381272 T/C cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11190604 1.000 rs3750626 chr10:102266316 C/T cg23241863 chr10:102295624 HIF1AN 0.67 5.13 0.42 1.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs886427 0.517 rs12918697 chr16:3002851 G/C cg27042294 chr16:2982532 FLYWCH1 0.21 4.56 0.38 1.2e-5 Metabolic syndrome; TGCT cis rs807669 0.903 rs807666 chr22:19160549 C/T cg02655711 chr22:19163373 SLC25A1 0.42 10.06 0.67 8.99e-18 Metabolite levels; TGCT cis rs826838 0.967 rs826856 chr12:39115434 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.76 -0.57 2.68e-12 Heart rate; TGCT cis rs1949733 1.000 rs1357481 chr4:8496221 A/T cg11789530 chr4:8429930 ACOX3 0.56 5.21 0.42 7.55e-7 Response to antineoplastic agents; TGCT cis rs6750047 0.549 rs151096 chr2:38316571 A/C cg07380506 chr2:38303506 CYP1B1 -0.59 -5.47 -0.44 2.39e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs7666738 0.830 rs4401456 chr4:98959902 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7904368 0.659 rs3740169 chr10:16873547 C/T cg14835575 chr10:16859367 RSU1 0.52 5.58 0.45 1.43e-7 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs9796 0.553 rs1869908 chr15:41257224 C/A cg18705301 chr15:41695430 NDUFAF1 0.57 7.44 0.56 1.47e-11 Menopause (age at onset); TGCT cis rs6087771 0.682 rs2038397 chr20:30217759 A/G cg18721089 chr20:30220636 NA -0.43 -5.37 -0.43 3.7e-7 Subcortical brain region volumes;Putamen volume; TGCT cis rs79387448 0.745 rs72993722 chr2:103124916 A/G cg09003973 chr2:102972529 NA 0.87 5.8 0.46 5.22e-8 Gut microbiota (bacterial taxa); TGCT cis rs11677370 0.561 rs10084170 chr2:3820204 G/C cg17052675 chr2:3827356 NA -0.46 -8.18 -0.59 2.9e-13 Type 2 diabetes; TGCT cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7226408 0.857 rs72887031 chr18:34472083 C/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs478222 0.930 rs510107 chr2:25319471 G/A cg01884057 chr2:25150051 NA -0.26 -4.82 -0.4 4.04e-6 Type 1 diabetes; TGCT cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg22166914 chr1:53195759 ZYG11B 0.37 6.17 0.48 8.84e-9 Monocyte count; TGCT cis rs7666738 0.830 rs28867388 chr4:98962794 A/T cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 0.669 rs8036703 chr15:76951040 A/G cg22467129 chr15:76604101 ETFA -0.44 -4.87 -0.4 3.36e-6 Blood metabolite levels; TGCT cis rs28374715 0.681 rs28728213 chr15:41653602 T/A cg18705301 chr15:41695430 NDUFAF1 -0.88 -14.18 -0.79 1e-27 Ulcerative colitis; TGCT cis rs34638657 0.732 rs62045964 chr16:82200920 T/C cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7584330 0.704 rs7602387 chr2:238356795 A/G cg14458575 chr2:238380390 NA 0.49 7.56 0.56 7.65e-12 Prostate cancer; TGCT cis rs8078723 1.000 rs8078723 chr17:38166879 A/G cg17467752 chr17:38218738 THRA 0.54 5.22 0.42 7.25e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs950776 0.642 rs7178007 chr15:78965254 G/A cg03762349 chr15:79060523 ADAMTS7 0.27 5.35 0.43 4.08e-7 Sudden cardiac arrest; TGCT cis rs4332037 0.539 rs11764590 chr7:2032803 C/T cg25834613 chr7:1915315 MAD1L1 -0.47 -4.51 -0.38 1.48e-5 Bipolar disorder; TGCT cis rs427394 0.632 rs377137 chr5:6740468 T/G cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs7666738 0.830 rs17483521 chr4:98974058 A/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT trans rs2243480 1.000 rs2533288 chr7:66056711 C/G cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg22920501 chr2:26401640 FAM59B -0.78 -6.26 -0.49 5.88e-9 Gut microbiome composition (summer); TGCT cis rs986417 0.818 rs2092722 chr14:61062890 T/A cg27398547 chr14:60952738 C14orf39 1.33 9.93 0.67 1.82e-17 Gut microbiota (bacterial taxa); TGCT cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 -0.95 -7.88 -0.58 1.45e-12 Platelet count; TGCT cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg15659132 chr6:26577336 NA 0.86 10.93 0.7 6.8e-20 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.698 rs17361805 chr1:46813967 C/T cg00765921 chr1:46154277 TMEM69 0.57 5.03 0.41 1.7e-6 Menopause (age at onset); TGCT cis rs8054556 0.740 rs11649612 chr16:29946670 T/C cg26859862 chr16:30389551 SEPT1 -0.53 -4.54 -0.38 1.31e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2832191 0.671 rs2832212 chr21:30511417 G/A cg24692254 chr21:30365293 RNF160 -0.61 -5.41 -0.44 3.08e-7 Dental caries; TGCT cis rs13191362 0.938 rs13213746 chr6:163167777 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.68 5.79 0.46 5.5e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs8180040 0.966 rs6792488 chr3:47503349 C/T cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg11494091 chr17:61959527 GH2 0.6 14.76 0.8 4.43e-29 Prudent dietary pattern; TGCT cis rs9549367 0.601 rs558869 chr13:113849932 G/T cg00898013 chr13:113819073 PROZ 0.53 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs208520 0.526 rs2881644 chr6:66803535 A/C cg07460842 chr6:66804631 NA 1.07 16.07 0.82 4.2e-32 Exhaled nitric oxide output; TGCT cis rs1541995 0.824 rs12903641 chr15:96239445 A/T cg00882281 chr15:96346592 NA 0.3 4.82 0.4 4.07e-6 Photic sneeze reflex; TGCT cis rs1062177 0.756 rs2915826 chr5:151119963 G/A cg00977110 chr5:151150581 G3BP1 -0.4 -4.67 -0.39 7.7e-6 Preschool internalizing problems; TGCT cis rs7546668 0.640 rs6675825 chr1:15811346 C/T cg17657618 chr1:15427654 KIAA1026 -0.25 -4.56 -0.38 1.19e-5 Glomerular filtration rate (creatinine); TGCT cis rs7523273 0.565 rs2796232 chr1:207900368 T/A cg22525895 chr1:207977042 MIR29B2 -0.32 -5.05 -0.41 1.53e-6 Schizophrenia; TGCT cis rs514406 0.861 rs4926577 chr1:53226788 C/A cg08859206 chr1:53392774 SCP2 0.4 5.97 0.47 2.38e-8 Monocyte count; TGCT cis rs12693043 0.727 rs35923732 chr2:175413376 G/A cg11778734 chr2:175439522 WIPF1 -0.4 -5.15 -0.42 9.9e-7 Urate levels (BMI interaction); TGCT cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs709400 0.628 rs2273700 chr14:103923414 A/G cg26031613 chr14:104095156 KLC1 0.86 9.43 0.65 2.96e-16 Body mass index; TGCT trans rs324780 0.544 rs1873342 chr12:83915004 G/C cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.29e-10 Vertical cup-disc ratio; TGCT cis rs3772130 1.000 rs62268732 chr3:121370455 T/G cg01951420 chr3:121553821 IQCB1;EAF2 0.55 5.02 0.41 1.77e-6 Cognitive performance; TGCT cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs12908161 0.959 rs1051168 chr15:85200520 G/T cg12863693 chr15:85201151 NMB 0.46 5.45 0.44 2.66e-7 Schizophrenia; TGCT cis rs6546537 1.000 rs6546535 chr2:69833382 G/T cg10773587 chr2:69614142 GFPT1 -0.65 -5.64 -0.45 1.09e-7 Serum thyroid-stimulating hormone levels; TGCT trans rs7618501 0.633 rs7628058 chr3:50039474 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.84 9.34 0.64 4.98e-16 Intelligence (multi-trait analysis); TGCT cis rs6977660 0.660 rs61670426 chr7:19790460 A/G cg05791153 chr7:19748676 TWISTNB 0.88 5.05 0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs7267979 0.789 rs6050472 chr20:25219852 A/G cg21995068 chr20:25989032 LOC100134868 -0.39 -4.54 -0.38 1.3e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1023500 0.596 rs5758562 chr22:42448238 C/G cg15557168 chr22:42548783 NA -0.19 -4.84 -0.4 3.73e-6 Schizophrenia; TGCT cis rs9653442 0.564 rs7601892 chr2:100789490 G/A cg07810366 chr2:100720526 AFF3 -0.35 -5.26 -0.43 6e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1055129 0.537 rs2467100 chr17:73949038 C/G cg08125733 chr17:73851984 WBP2 0.55 5.32 0.43 4.7e-7 White matter hyperintensity burden; TGCT cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg08439880 chr3:133502540 NA -0.35 -6.91 -0.53 2.29e-10 Iron status biomarkers; TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs3806843 0.966 rs2563261 chr5:140137713 G/T cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.53e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs10832169 0.967 rs10832172 chr11:14072410 T/C cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs6089829 0.962 rs2872543 chr20:61665017 G/A cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1448094 0.717 rs7298614 chr12:86296513 C/T cg00310523 chr12:86230176 RASSF9 0.34 4.77 0.39 5e-6 Major depressive disorder; TGCT cis rs2112347 0.502 rs34342 chr5:74934213 A/C cg19683494 chr5:74908142 NA -0.65 -6.07 -0.48 1.42e-8 Body mass index (joint analysis main effects and smoking interaction);Waist circumference;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Hip circumference;Body mass index;Body mass index in physically active individuals;Obesity; TGCT cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg05985448 chr10:134359359 INPP5A 0.21 4.67 0.39 7.69e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs1496653 0.602 rs35245309 chr3:23419624 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs7772486 0.566 rs735536 chr6:146036832 A/C cg23711669 chr6:146136114 FBXO30 -0.89 -10.12 -0.67 6.37e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs908922 0.676 rs6587681 chr1:152512135 C/T cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs1800469 1.000 rs2317130 chr19:41861674 C/T cg09537434 chr19:41945824 ATP5SL -0.52 -4.77 -0.39 5.08e-6 Colorectal cancer; TGCT cis rs2439831 0.850 rs2439832 chr15:43779686 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.98 7.72 0.57 3.37e-12 Lung cancer in ever smokers; TGCT cis rs3734905 1.000 rs12526225 chr6:169861325 T/C cg05229362 chr6:169789120 NA -0.48 -4.44 -0.37 1.94e-5 HIV-1 control; TGCT cis rs1949733 0.701 rs1880024 chr4:8454639 A/G cg13073564 chr4:8508604 NA -0.42 -4.65 -0.39 8.41e-6 Response to antineoplastic agents; TGCT cis rs875971 0.862 rs801203 chr7:66023012 A/G cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs4077515 0.874 rs3812575 chr9:139293259 T/C cg13741927 chr9:139327495 INPP5E -0.19 -4.59 -0.38 1.05e-5 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT trans rs4332037 0.539 rs56016347 chr7:2060126 C/T cg25206134 chr2:45395956 NA 0.96 7.31 0.55 2.89e-11 Bipolar disorder; TGCT cis rs9388451 0.626 rs2875881 chr6:126072853 C/G cg10911889 chr6:126070802 HEY2 0.5 4.69 0.39 7.17e-6 Brugada syndrome; TGCT cis rs939658 0.805 rs6495374 chr15:79434031 C/T cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs2688608 0.934 rs2675679 chr10:75658581 C/T cg04320760 chr10:75533139 FUT11 -0.29 -4.44 -0.37 1.96e-5 Inflammatory bowel disease; TGCT cis rs7044106 0.762 rs4142158 chr9:123410819 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.6 0.51 1.08e-9 Hip circumference adjusted for BMI; TGCT cis rs9810089 0.934 rs1279949 chr3:135996870 T/A cg12473912 chr3:136751656 NA 0.35 4.9 0.4 2.9e-6 Gestational age at birth (child effect); TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs7246657 0.943 rs10409204 chr19:37917692 G/A cg18154014 chr19:37997991 ZNF793 0.94 6.42 0.5 2.6e-9 Coronary artery calcification; TGCT cis rs7666738 0.830 rs7664340 chr4:99037820 C/T cg17366294 chr4:99064904 C4orf37 0.72 7.54 0.56 8.52e-12 Colonoscopy-negative controls vs population controls; TGCT trans rs7618501 0.635 rs7635002 chr3:49989155 T/G cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.92 0.67 1.99e-17 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg11062466 chr8:58055876 NA 0.42 4.48 0.37 1.71e-5 Developmental language disorder (linguistic errors); TGCT trans rs7618501 0.602 rs2240327 chr3:50113034 C/T cg21659725 chr3:3221576 CRBN 0.73 8.48 0.61 5.64e-14 Intelligence (multi-trait analysis); TGCT cis rs12477438 1.000 rs57846982 chr2:99921574 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -6.02 -0.48 1.87e-8 Chronic sinus infection; TGCT cis rs910316 0.967 rs10246 chr14:75544470 T/A cg23033748 chr14:75592666 NEK9 0.28 4.76 0.39 5.27e-6 Height; TGCT cis rs12908161 0.920 rs35738019 chr15:85280210 T/C cg12863693 chr15:85201151 NMB 0.44 5.21 0.42 7.63e-7 Schizophrenia; TGCT cis rs3862435 0.518 rs2601169 chr15:90913890 T/C cg14166756 chr15:90894880 ZNF774 -0.31 -4.88 -0.4 3.17e-6 Response to exercise (triglyceride level interaction); TGCT trans rs7824557 0.507 rs7010590 chr8:11062882 C/T cg15556689 chr8:8085844 FLJ10661 0.72 7.01 0.53 1.34e-10 Retinal vascular caliber; TGCT cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg04546413 chr19:29218101 NA 0.84 6.82 0.52 3.52e-10 Methadone dose in opioid dependence; TGCT cis rs9291683 0.609 rs12507050 chr4:10007305 G/T cg00071950 chr4:10020882 SLC2A9 0.7 9.44 0.65 2.86e-16 Bone mineral density; TGCT cis rs7044106 0.762 rs10760107 chr9:123383630 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 4.57 0.38 1.14e-5 Hip circumference adjusted for BMI; TGCT cis rs11098499 0.954 rs12502423 chr4:120424172 A/C cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs4631830 0.863 rs10826125 chr10:51530505 G/A cg10326726 chr10:51549505 MSMB -0.26 -5.3 -0.43 5.17e-7 Prostate-specific antigen levels; TGCT trans rs6089829 0.925 rs4809270 chr20:61676709 C/A cg17470723 chr8:74884337 TCEB1 0.78 6.87 0.53 2.7e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs4409675 0.576 rs1474908 chr1:28213213 C/T cg23691781 chr1:28212827 C1orf38 -0.27 -5.28 -0.43 5.57e-7 Corneal astigmatism; TGCT cis rs9818758 0.607 rs66991555 chr3:49228643 A/G cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs939574 1.000 rs7574937 chr2:220099331 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.04 5.78 0.46 5.83e-8 Platelet distribution width; TGCT cis rs12142240 0.698 rs67200518 chr1:46835777 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs1153858 0.945 rs1974981 chr15:45729123 C/T cg26924012 chr15:45694286 SPATA5L1 -0.99 -12.56 -0.75 7.42e-24 Homoarginine levels; TGCT cis rs4253772 0.550 rs738444 chr22:46721088 C/T cg24881330 chr22:46731750 TRMU 0.94 6.36 0.5 3.54e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs13242816 0.881 rs12706091 chr7:116130783 G/C cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT cis rs12477438 0.501 rs12613624 chr2:99732741 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.91 -10.3 -0.68 2.42e-18 Chronic sinus infection; TGCT cis rs17376456 0.877 rs56373208 chr5:93491276 C/A cg21475434 chr5:93447410 FAM172A 0.63 4.63 0.38 8.98e-6 Diabetic retinopathy; TGCT cis rs769267 0.899 rs67720221 chr19:19440864 C/T cg03709012 chr19:19516395 GATAD2A -0.67 -5.79 -0.46 5.55e-8 Tonsillectomy; TGCT trans rs7615952 0.733 rs13314847 chr3:125644788 C/T cg07211511 chr3:129823064 LOC729375 -0.48 -8.02 -0.58 6.91e-13 Blood pressure (smoking interaction); TGCT cis rs2963155 0.518 rs853176 chr5:142636456 A/G cg17617527 chr5:142782415 NR3C1 -0.83 -6.97 -0.53 1.63e-10 Breast cancer; TGCT cis rs9527 0.544 rs3781280 chr10:104863843 T/G cg15744005 chr10:104629667 AS3MT -0.42 -4.84 -0.4 3.84e-6 Arsenic metabolism; TGCT cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg03517284 chr6:25882590 NA -0.69 -7.5 -0.56 1.07e-11 Blood metabolite levels; TGCT cis rs651907 0.535 rs11714444 chr3:101513682 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs2289577 0.698 rs17513180 chr6:90634912 A/G cg19995471 chr6:90052148 UBE2J1 -0.31 -4.59 -0.38 1.08e-5 Cognitive performance; TGCT cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg18654377 chr3:49208889 KLHDC8B -0.37 -4.69 -0.39 7.12e-6 Parkinson's disease; TGCT cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.69e-9 Blood metabolite levels; TGCT cis rs75229567 0.717 rs74527680 chr12:70235392 A/G cg10114359 chr12:70132523 RAB3IP 1.55 7.66 0.57 4.5e-12 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs7727544 0.547 rs56083751 chr5:131664638 T/A cg14196790 chr5:131705035 SLC22A5 0.34 4.79 0.4 4.62e-6 Blood metabolite levels; TGCT cis rs11971779 0.941 rs7802779 chr7:139122579 G/T cg07862535 chr7:139043722 LUC7L2 0.72 5.52 0.44 1.88e-7 Diisocyanate-induced asthma; TGCT cis rs7611238 0.560 rs62288360 chr3:195089307 T/C cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs2760061 0.603 rs697762 chr1:228192410 G/A cg18477163 chr1:228402036 OBSCN 0.34 6.91 0.53 2.25e-10 Diastolic blood pressure; TGCT cis rs11874712 0.527 rs12709735 chr18:43687087 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.49 4.86 0.4 3.47e-6 Migraine - clinic-based; TGCT trans rs10953454 1.000 rs35146170 chr7:104472431 T/C cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.54e-10 Obesity; TGCT cis rs7017914 0.967 rs6998786 chr8:71694630 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT trans rs17471911 0.708 rs80045285 chr10:100776216 G/A cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs17331151 0.573 rs79664140 chr3:52866936 A/G cg07884673 chr3:53033167 SFMBT1 0.49 5.66 0.45 1.01e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6977660 0.714 rs10276518 chr7:19781325 C/A cg05791153 chr7:19748676 TWISTNB 0.89 5.08 0.41 1.37e-6 Thyroid stimulating hormone; TGCT cis rs5769765 0.908 rs138867 chr22:50207703 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.05 10.64 0.69 3.55e-19 Schizophrenia; TGCT cis rs9393777 0.720 rs13217285 chr6:26999845 C/T cg16898833 chr6:26189333 HIST1H4D 1.01 5.9 0.47 3.18e-8 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.566 rs9348706 chr6:26065481 G/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.19e-6 Height; TGCT cis rs9549260 0.755 rs7986407 chr13:41179798 A/G cg21288729 chr13:41239152 FOXO1 1.0 9.93 0.67 1.88e-17 Red blood cell count; TGCT cis rs9473924 1.000 rs9463656 chr6:50859655 A/G cg14470998 chr6:50812995 TFAP2B 0.61 4.48 0.37 1.7e-5 Body mass index; TGCT cis rs826838 0.967 rs1719853 chr12:39128515 A/G cg26384229 chr12:38710491 ALG10B -0.83 -7.31 -0.55 2.88e-11 Heart rate; TGCT cis rs4253772 0.591 rs6007726 chr22:46650858 A/C cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT trans rs1814175 0.654 rs7482446 chr11:49779020 A/G cg03929089 chr4:120376271 NA -0.69 -8.17 -0.59 3.03e-13 Height; TGCT cis rs2463822 0.858 rs2463836 chr11:62126494 A/G cg23876832 chr11:62092739 NA 0.64 4.72 0.39 6.28e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7027203 0.521 rs9299412 chr9:96523268 G/T cg13679303 chr9:96623674 NA -0.53 -7.48 -0.56 1.18e-11 DNA methylation (variation); TGCT cis rs6951245 0.638 rs4720486 chr7:1146764 G/A cg23708337 chr7:1209742 NA 0.44 4.97 0.41 2.16e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7089973 0.604 rs2420067 chr10:116590348 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.75 0.46 6.46e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7572733 0.555 rs35563720 chr2:198923075 A/G cg00792783 chr2:198669748 PLCL1 0.59 5.15 0.42 1.01e-6 Dermatomyositis; TGCT cis rs8179 0.645 rs6960181 chr7:92277477 C/T cg15732164 chr7:92237376 CDK6 -0.29 -5.06 -0.41 1.46e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs889512 0.642 rs72802352 chr16:75240883 G/A cg08092318 chr16:75625571 NA 0.74 4.63 0.38 9.14e-6 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs916888 0.821 rs70600 chr17:44860021 C/T cg15921436 chr17:44337874 NA 0.51 6.96 0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Vitiligo; TGCT cis rs5750830 0.594 rs1010169 chr22:39778167 C/T cg02038168 chr22:39784481 NA 0.67 5.78 0.46 5.82e-8 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.806 rs7007394 chr8:11094566 G/A cg21775007 chr8:11205619 TDH -0.5 -4.55 -0.38 1.27e-5 Retinal vascular caliber; TGCT cis rs2159324 1.000 rs2159324 chr19:45695738 A/G cg24080119 chr19:45644694 NA 0.3 4.79 0.4 4.61e-6 Quantitative traits; TGCT cis rs9914544 0.545 rs2386404 chr17:18769349 T/C cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs6032067 0.516 rs6032087 chr20:43902305 A/G cg16667508 chr20:43936853 MATN4;RBPJL -0.38 -5.96 -0.47 2.38e-8 Blood protein levels; TGCT cis rs6570726 0.764 rs448258 chr6:145869145 C/A cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9682041 0.696 rs11709437 chr3:170085568 T/G cg11886554 chr3:170076028 SKIL 0.6 4.76 0.39 5.35e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs1218582 0.710 rs7553195 chr1:154837796 T/C cg09359103 chr1:154839909 KCNN3 -0.7 -13.89 -0.78 4.86e-27 Prostate cancer; TGCT cis rs2688608 0.592 rs10824031 chr10:75509273 C/T cg19442545 chr10:75533431 FUT11 -0.36 -5.74 -0.46 6.99e-8 Inflammatory bowel disease; TGCT cis rs4285028 0.747 rs12634032 chr3:121524575 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -1.03 -8.75 -0.62 1.26e-14 Multiple sclerosis; TGCT cis rs6912958 0.559 rs107689 chr6:88069333 G/T cg08069147 chr6:88032118 GJB7;C6orf162 0.69 7.0 0.53 1.43e-10 Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs13122054 chr4:98972974 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 0.690 rs207091 chr6:66799847 G/T cg07460842 chr6:66804631 NA -0.94 -9.91 -0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs6879260 1.000 rs7706951 chr5:179733407 C/T cg13944838 chr5:179740914 GFPT2 -0.4 -6.42 -0.5 2.66e-9 Height; TGCT cis rs11690935 0.632 rs1607254 chr2:172626552 A/G cg13550731 chr2:172543902 DYNC1I2 0.68 6.0 0.47 2.02e-8 Schizophrenia; TGCT cis rs2228479 0.867 rs73276534 chr16:89950557 A/G cg06558623 chr16:89946397 TCF25 0.4 4.73 0.39 5.89e-6 Skin colour saturation; TGCT cis rs11098499 0.863 rs3822190 chr4:120428098 G/A cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.36e-9 Corneal astigmatism; TGCT cis rs2439831 1.000 rs689754 chr15:43775895 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.99 7.5 0.56 1.08e-11 Lung cancer in ever smokers; TGCT cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs7666738 0.830 rs11942114 chr4:99066261 C/G cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.9e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7010267 0.773 rs4355801 chr8:119923873 A/G cg17171407 chr8:119960777 TNFRSF11B -0.28 -4.94 -0.41 2.46e-6 Total body bone mineral density (age 45-60); TGCT cis rs1153858 1.000 rs4775911 chr15:45649787 G/T cg14582100 chr15:45693742 SPATA5L1 -0.49 -5.75 -0.46 6.62e-8 Homoarginine levels; TGCT cis rs17152411 0.895 rs17151676 chr10:126583640 T/C cg07906193 chr10:126599966 NA 0.41 5.06 0.41 1.48e-6 Height; TGCT cis rs11785400 0.701 rs9297967 chr8:143723002 A/C cg10596483 chr8:143751796 JRK 0.53 5.23 0.43 7.02e-7 Schizophrenia; TGCT cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.0 8.22 0.59 2.32e-13 Platelet count; TGCT cis rs7666738 0.830 rs34461023 chr4:99023751 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.24 0.43 6.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 0.626 rs4855882 chr3:49715354 G/T cg03034192 chr3:50606346 HEMK1;C3orf18 0.37 4.8 0.4 4.56e-6 Menarche (age at onset); TGCT cis rs7727544 0.716 rs4594848 chr5:131586598 C/A cg22598563 chr5:131563921 P4HA2 -0.28 -4.55 -0.38 1.27e-5 Blood metabolite levels; TGCT cis rs514406 0.505 rs447581 chr1:53177098 T/C cg08859206 chr1:53392774 SCP2 -0.36 -5.13 -0.42 1.1e-6 Monocyte count; TGCT cis rs854765 0.663 rs12941550 chr17:17753828 C/A cg04398451 chr17:18023971 MYO15A 0.3 4.6 0.38 1.02e-5 Total body bone mineral density; TGCT cis rs72945132 0.882 rs7116191 chr11:70159781 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7191700 0.644 rs918738 chr16:11439679 C/G cg00044050 chr16:11439710 C16orf75 -0.97 -12.5 -0.75 1.05e-23 Multiple sclerosis; TGCT cis rs875971 0.929 rs12535036 chr7:65964063 G/T cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg11890956 chr21:40555474 PSMG1 1.1 12.36 0.74 2.27e-23 Cognitive function; TGCT cis rs111803315 0.661 rs112716995 chr14:59978004 T/C cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs7119 0.651 rs12902072 chr15:77848732 T/C cg27398640 chr15:77910606 LINGO1 -0.28 -5.2 -0.42 7.98e-7 Type 2 diabetes; TGCT cis rs751728 0.689 rs3763257 chr6:33773696 T/A cg00334056 chr6:33755658 LEMD2 -0.26 -4.75 -0.39 5.41e-6 Crohn's disease; TGCT cis rs10256972 0.524 rs6945202 chr7:1116558 T/C cg03188948 chr7:1209495 NA 0.44 5.38 0.43 3.64e-7 Longevity;Endometriosis; TGCT cis rs986417 0.818 rs761557 chr14:61077484 C/T cg13065475 chr14:61176368 SIX4 -0.32 -4.53 -0.38 1.34e-5 Gut microbiota (bacterial taxa); TGCT cis rs524281 0.861 rs10896077 chr11:65851733 C/G cg00563793 chr11:65837595 PACS1 0.56 4.68 0.39 7.32e-6 Electroencephalogram traits; TGCT cis rs7772486 0.846 rs2892453 chr6:146377717 C/A cg05347473 chr6:146136440 FBXO30 0.51 4.82 0.4 4.07e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs2688608 0.672 rs2688622 chr10:75688981 C/A cg13918328 chr10:52500089 ASAH2B 0.67 6.78 0.52 4.42e-10 Inflammatory bowel disease; TGCT cis rs7017914 0.905 rs3110255 chr8:71938050 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.93 -0.4 2.63e-6 Bone mineral density; TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg02073558 chr3:44770973 ZNF501 0.64 6.22 0.49 7.06e-9 Depressive symptoms; TGCT cis rs6901250 0.610 rs9400964 chr6:117144808 G/T cg12892004 chr6:117198278 RFX6 0.42 5.07 0.41 1.4e-6 C-reactive protein levels; TGCT cis rs2204008 0.774 rs7305085 chr12:38263511 C/T cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs2594989 0.943 rs2454500 chr3:11500103 C/T cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.58e-5 Circulating chemerin levels; TGCT trans rs9929218 0.529 rs35854485 chr16:68730855 C/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.53 6.71 0.52 6.1e-10 Colorectal cancer; TGCT cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg13732083 chr21:47605072 C21orf56 -0.35 -4.51 -0.38 1.5e-5 Testicular germ cell tumor; TGCT cis rs1865760 0.516 rs9379818 chr6:26023206 G/T cg16482183 chr6:26056742 HIST1H1C 0.59 5.2 0.42 7.96e-7 Height; TGCT cis rs9914544 0.966 rs9915346 chr17:18787931 G/A cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.41 1.36e-6 Educational attainment (years of education); TGCT cis rs7582180 0.663 rs4850930 chr2:100990955 T/C cg08017756 chr2:100939284 LONRF2 -0.31 -5.14 -0.42 1.06e-6 Intelligence (multi-trait analysis); TGCT cis rs4975709 0.569 rs4975743 chr5:1859941 G/T cg14773178 chr5:1868261 NA 0.34 5.62 0.45 1.21e-7 Cardiovascular disease risk factors; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg04234412 chr22:24373322 LOC391322 0.92 8.49 0.61 5.4e-14 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs16939607 1.000 rs16939605 chr8:79005815 C/G cg21244580 chr8:79934476 NA 0.48 4.77 0.39 5e-6 White blood cell count; TGCT cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg20607798 chr8:58055168 NA 0.44 4.54 0.38 1.32e-5 Developmental language disorder (linguistic errors); TGCT cis rs7582180 0.627 rs4851312 chr2:101011241 G/A cg14675211 chr2:100938903 LONRF2 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.557 rs1250097 chr4:1238338 C/T cg20887711 chr4:1340912 KIAA1530 -0.58 -4.97 -0.41 2.17e-6 Obesity-related traits; TGCT cis rs7715806 0.500 rs17563589 chr5:74980019 A/G cg19683494 chr5:74908142 NA 0.57 4.95 0.41 2.35e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs2180341 0.694 rs2875972 chr6:127585522 T/C cg24812749 chr6:127587940 RNF146 0.83 6.69 0.51 6.91e-10 Breast cancer; TGCT cis rs1018836 0.632 rs6988302 chr8:91477660 C/T cg16814680 chr8:91681699 NA -0.79 -8.28 -0.6 1.65e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.791 rs10010438 chr4:99022177 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.623 rs28872016 chr9:5253558 T/G cg02405213 chr9:5042618 JAK2 -0.71 -8.34 -0.6 1.18e-13 Pediatric autoimmune diseases; TGCT cis rs12497850 0.864 rs12493001 chr3:49181885 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.4 0.44 3.31e-7 Parkinson's disease; TGCT cis rs1371867 0.846 rs1788194 chr8:101277916 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -6.83 -0.52 3.32e-10 Atrioventricular conduction; TGCT cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg10047753 chr17:41438598 NA 0.9 8.32 0.6 1.37e-13 Menopause (age at onset); TGCT trans rs7819412 0.775 rs4841490 chr8:10936891 T/C cg15556689 chr8:8085844 FLJ10661 -0.84 -8.16 -0.59 3.26e-13 Triglycerides; TGCT cis rs6964587 1.000 rs7806184 chr7:91601978 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs13064447 0.935 rs7624347 chr3:12756045 T/A cg20675869 chr3:12750130 NA 0.19 4.94 0.41 2.5e-6 Major depression and alcohol dependence; TGCT cis rs9486719 1.000 rs2499816 chr6:96878206 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7631605 0.819 rs1392748 chr3:37265313 T/C cg17445812 chr3:36986805 TRANK1 0.22 4.78 0.39 4.77e-6 Cerebrospinal P-tau181p levels; TGCT cis rs12049351 0.719 rs34804247 chr1:229620685 C/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs314370 0.570 rs314314 chr7:100423841 C/T cg10426581 chr7:100472382 SRRT 0.72 7.45 0.56 1.37e-11 Resting heart rate; TGCT cis rs2242116 0.896 rs724449 chr3:46935681 C/T cg23352942 chr3:46931381 PTH1R -0.37 -5.91 -0.47 3.05e-8 Birth weight; TGCT cis rs2153535 0.580 rs9406143 chr6:8444583 C/T cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs2070488 1.000 rs4147025 chr3:38456531 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 9.06e-17 Electrocardiographic conduction measures; TGCT cis rs12762955 0.561 rs7075141 chr10:1091195 C/T cg20503657 chr10:835505 NA -0.37 -4.86 -0.4 3.47e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs7666738 0.606 rs6839946 chr4:99076132 A/C cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.59e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9372498 0.536 rs62422224 chr6:118941116 G/A cg07617317 chr6:118971624 C6orf204 0.47 4.95 0.41 2.33e-6 Diastolic blood pressure; TGCT cis rs62209 0.752 rs72772071 chr10:11011821 A/G cg26901096 chr10:10994189 LOC254312 0.43 6.99 0.53 1.46e-10 Alzheimer's disease (late onset); TGCT cis rs7552404 1.000 rs2133134 chr1:76179587 G/A cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7226408 0.857 rs17652450 chr18:34473583 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs3806933 0.522 rs17553936 chr5:110454681 A/G cg04022379 chr5:110408740 TSLP 0.59 6.25 0.49 5.92e-9 Eosinophilic esophagitis; TGCT cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg06238570 chr21:40685208 BRWD1 0.72 6.84 0.52 3.16e-10 Cognitive function; TGCT cis rs1008375 0.933 rs4698637 chr4:17632843 A/T cg10189774 chr4:17578691 LAP3 0.65 5.78 0.46 5.69e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17102423 0.531 rs2763888 chr14:65571493 T/C cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.67e-9 Obesity-related traits; TGCT cis rs4819852 0.958 rs9606203 chr22:19972118 C/A cg07821417 chr22:19972146 ARVCF 0.2 4.94 0.41 2.45e-6 Pulse pressure; TGCT cis rs67311347 0.911 rs6776044 chr3:40377503 T/G cg13683864 chr3:40499215 RPL14 -1.09 -11.46 -0.72 3.52e-21 Renal cell carcinoma; TGCT cis rs2657888 1.000 rs7309685 chr12:56935413 A/G cg23002907 chr12:56915593 RBMS2 -0.48 -6.6 -0.51 1.08e-9 Adiponectin levels; TGCT trans rs7819412 0.807 rs9657519 chr8:10945439 A/G cg06636001 chr8:8085503 FLJ10661 -0.8 -7.43 -0.56 1.52e-11 Triglycerides; TGCT cis rs9325144 0.647 rs7316392 chr12:39064381 T/G cg26384229 chr12:38710491 ALG10B -0.55 -5.1 -0.42 1.22e-6 Morning vs. evening chronotype; TGCT cis rs910316 0.789 rs4899552 chr14:75667921 C/A cg11812906 chr14:75593930 NEK9 -0.61 -5.51 -0.44 2.01e-7 Height; TGCT cis rs9807989 0.507 rs1833174 chr2:103034843 T/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg11644478 chr21:40555479 PSMG1 1.03 11.12 0.71 2.32e-20 Cognitive function; TGCT cis rs6940638 0.662 rs6915678 chr6:27235866 T/G cg26531700 chr6:26746687 NA -0.58 -4.98 -0.41 2.05e-6 Intelligence (multi-trait analysis); TGCT cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.7 0.46 8.33e-8 Height; TGCT cis rs7635838 0.718 rs2594973 chr3:11395821 C/G cg00170343 chr3:11313890 ATG7 0.65 6.48 0.5 1.97e-9 HDL cholesterol; TGCT cis rs7666738 0.830 rs11727235 chr4:98946331 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs523522 0.962 rs12309824 chr12:120990582 A/C cg27279351 chr12:120934652 DYNLL1 0.74 6.43 0.5 2.45e-9 High light scatter reticulocyte count; TGCT cis rs644799 0.511 rs10831420 chr11:95478209 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.59 5.76 0.46 6.12e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs116095464 0.558 rs6882584 chr5:223411 A/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs7772486 0.748 rs2748484 chr6:146333653 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.9 0.4 2.93e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.8e-7 Gut microbiome composition (summer); TGCT cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs10791097 0.694 rs1893018 chr11:130756632 T/C cg14779329 chr11:130786720 SNX19 0.29 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7568458 0.870 rs1058588 chr2:85808871 A/G cg02493740 chr2:85810744 VAMP5 0.27 4.77 0.39 4.99e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4836694 0.517 rs1017112 chr9:132936804 A/G cg05251000 chr9:132935664 FREQ 0.53 6.02 0.48 1.8e-8 Alzheimer's disease (cognitive decline); TGCT cis rs2147959 0.714 rs6670856 chr1:228723355 G/T cg22700015 chr1:228743131 NA -0.53 -4.45 -0.37 1.87e-5 Adult asthma; TGCT cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg23719950 chr11:63933701 MACROD1 -0.71 -5.91 -0.47 3.06e-8 Mean platelet volume; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg04234412 chr22:24373322 LOC391322 -0.9 -10.44 -0.68 1.07e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6433857 0.534 rs1157535 chr2:181361736 T/A cg23363182 chr2:181467187 NA -0.3 -4.57 -0.38 1.17e-5 Body mass index; TGCT cis rs4499344 0.504 rs259248 chr19:33148041 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.76 7.52 0.56 9.49e-12 Mean platelet volume; TGCT cis rs10256972 0.967 rs7799110 chr7:1039065 A/G cg16145915 chr7:1198662 ZFAND2A -0.4 -4.76 -0.39 5.31e-6 Longevity;Endometriosis; TGCT cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg10047753 chr17:41438598 NA 0.96 9.86 0.66 2.71e-17 Menopause (age at onset); TGCT cis rs72781680 0.800 rs56398785 chr2:24091515 T/A cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs713587 0.967 rs6749422 chr2:25150011 C/G cg15423357 chr2:25149977 NA 0.63 6.47 0.5 2.01e-9 Body mass index in non-asthmatics; TGCT cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs11711311 1.000 rs9288984 chr3:113525956 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.64 -0.51 8.96e-10 IgG glycosylation; TGCT cis rs10875746 0.807 rs12297004 chr12:48453820 A/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg06558623 chr16:89946397 TCF25 0.53 6.84 0.52 3.24e-10 Skin colour saturation; TGCT cis rs10206020 0.842 rs7590900 chr2:1574902 A/G cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs9325144 0.513 rs12313652 chr12:38665412 G/A cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs7786877 0.587 rs56328569 chr7:100202219 C/G cg19543017 chr7:100164136 AGFG2 -0.32 -4.64 -0.38 8.85e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs908922 0.676 rs568661 chr1:152519787 C/A cg20991723 chr1:152506922 NA 0.45 6.09 0.48 1.33e-8 Hair morphology; TGCT cis rs459571 0.959 rs465535 chr9:136910905 C/T cg13789015 chr9:136890014 NCRNA00094 0.39 6.81 0.52 3.72e-10 Platelet distribution width; TGCT cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg20607798 chr8:58055168 NA -0.5 -4.66 -0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs208520 0.690 rs7764570 chr6:66827600 G/C cg07460842 chr6:66804631 NA -0.87 -8.37 -0.6 1.05e-13 Exhaled nitric oxide output; TGCT cis rs62103177 0.608 rs34383580 chr18:77833263 A/G cg07235805 chr18:78004237 PARD6G -0.51 -4.98 -0.41 2.11e-6 Opioid sensitivity; TGCT trans rs7726839 0.540 rs11738281 chr5:662547 T/C cg25482853 chr8:67687455 SGK3 1.23 10.87 0.7 9.57e-20 Obesity-related traits; TGCT cis rs11577318 0.853 rs2276712 chr1:26627478 T/C cg04990556 chr1:26633338 UBXN11 -0.63 -5.83 -0.46 4.58e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs9660180 0.836 rs72634845 chr1:1704899 G/A cg03396347 chr1:1875803 NA -0.36 -6.58 -0.51 1.19e-9 Body mass index; TGCT cis rs3816788 0.620 rs11783414 chr8:21773384 A/G cg17168535 chr8:21777572 XPO7 -0.78 -7.81 -0.57 2.09e-12 Lung cancer in ever smokers; TGCT cis rs7914558 0.966 rs746293 chr10:104897254 G/T cg15744005 chr10:104629667 AS3MT -0.42 -5.24 -0.43 6.69e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17270561 0.887 rs717551 chr6:25855624 T/C cg17691542 chr6:26056736 HIST1H1C 0.82 4.88 0.4 3.15e-6 Iron status biomarkers; TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg21672276 chr3:44754072 ZNF502 -0.45 -5.0 -0.41 1.94e-6 Depressive symptoms; TGCT trans rs7618501 0.501 rs35275715 chr3:49959148 A/G cg21659725 chr3:3221576 CRBN 0.72 8.08 0.59 4.98e-13 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg09177884 chr7:1199841 ZFAND2A -0.56 -5.46 -0.44 2.48e-7 Longevity;Endometriosis; TGCT cis rs6933660 0.745 rs9397405 chr6:151736084 G/T cg17179660 chr6:151773299 C6orf211;RMND1 -0.51 -4.62 -0.38 9.46e-6 Menarche (age at onset); TGCT cis rs7178424 0.875 rs7179506 chr15:62187955 T/G cg00456672 chr15:62358751 C2CD4A -0.31 -4.69 -0.39 7.14e-6 Height; TGCT cis rs10927875 0.631 rs945418 chr1:16344730 T/C cg22431228 chr1:16359049 CLCNKA -0.25 -4.64 -0.38 8.84e-6 Dilated cardiomyopathy; TGCT cis rs2230307 0.536 rs834278 chr1:100510882 T/C cg24955406 chr1:100503596 HIAT1 0.74 4.86 0.4 3.41e-6 Carotid intima media thickness; TGCT cis rs6671200 0.607 rs10874908 chr1:95704151 C/G cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg05890377 chr2:74357713 NA 0.5 6.75 0.52 5.16e-10 Gestational age at birth (maternal effect); TGCT cis rs3892630 0.619 rs61062732 chr19:33304717 T/C cg22980127 chr19:33182716 NUDT19 0.74 6.02 0.48 1.84e-8 Red blood cell traits; TGCT cis rs711245 1.000 rs848602 chr2:36778372 G/A cg15105969 chr2:36825350 FEZ2 0.55 4.84 0.4 3.73e-6 Height; TGCT cis rs1878931 0.501 rs42329 chr16:3425524 G/A cg22508957 chr16:3507546 NAT15 0.39 5.15 0.42 9.92e-7 Body mass index (adult); TGCT cis rs12477438 0.520 rs7604557 chr2:99747829 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.05 0.63 2.42e-15 Chronic sinus infection; TGCT cis rs7824557 0.602 rs11784458 chr8:11204184 G/A cg21775007 chr8:11205619 TDH 0.69 6.8 0.52 3.88e-10 Retinal vascular caliber; TGCT cis rs78461346 0.706 rs76797925 chr17:80476993 G/C cg15014069 chr17:80540666 FOXK2 0.38 5.0 0.41 1.91e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs8078723 1.000 rs6503530 chr17:38161823 T/C cg17467752 chr17:38218738 THRA 0.54 5.22 0.42 7.25e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs733175 0.855 rs9291641 chr4:10007259 C/T cg11266682 chr4:10021025 SLC2A9 0.48 4.56 0.38 1.21e-5 Psychosis and Alzheimer's disease; TGCT cis rs7681440 0.835 rs6532198 chr4:90798870 C/T cg20003494 chr4:90757398 SNCA -0.62 -5.94 -0.47 2.7e-8 Dementia with Lewy bodies; TGCT cis rs7937682 0.855 rs11213985 chr11:111581521 C/A cg09085632 chr11:111637200 PPP2R1B -1.12 -12.34 -0.74 2.58e-23 Primary sclerosing cholangitis; TGCT cis rs7119038 0.686 rs55894437 chr11:118607417 C/T cg19308663 chr11:118741387 NA 0.23 4.54 0.38 1.29e-5 Sjögren's syndrome; TGCT cis rs9527 0.545 rs11191602 chr10:104954219 C/T cg15744005 chr10:104629667 AS3MT -0.41 -4.78 -0.39 4.88e-6 Arsenic metabolism; TGCT cis rs709400 0.550 rs942865 chr14:104015250 G/A cg12935359 chr14:103987150 CKB -0.46 -6.02 -0.48 1.87e-8 Body mass index; TGCT cis rs7772486 0.720 rs7752286 chr6:146072662 C/T cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 1.000 rs28360661 chr21:40681972 G/C cg17971929 chr21:40555470 PSMG1 0.95 8.7 0.62 1.67e-14 Cognitive function; TGCT cis rs7267979 0.565 rs6076364 chr20:25556801 T/C cg03522245 chr20:25566470 NINL -0.44 -4.59 -0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11763147 1 rs11763147 chr7:65326821 C/T cg00343986 chr7:65444356 GUSB -0.25 -6.04 -0.48 1.67e-8 Corneal structure; TGCT cis rs6570726 1.000 rs436066 chr6:145847127 C/T cg05347473 chr6:146136440 FBXO30 0.49 4.44 0.37 1.96e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.772 rs6699043 chr1:154913021 T/C cg16680214 chr1:154839983 KCNN3 -0.35 -7.11 -0.54 8.04e-11 Prostate cancer; TGCT cis rs2153535 0.580 rs7741403 chr6:8530578 C/T cg07606381 chr6:8435919 SLC35B3 -0.52 -4.85 -0.4 3.57e-6 Motion sickness; TGCT cis rs826838 0.904 rs10880981 chr12:38763911 G/A cg26384229 chr12:38710491 ALG10B 1.08 10.86 0.7 1.01e-19 Heart rate; TGCT cis rs6570726 0.846 rs6570698 chr6:145918635 C/G cg05347473 chr6:146136440 FBXO30 0.5 4.59 0.38 1.07e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2742417 0.603 rs2673055 chr3:45772772 G/A cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs12477438 0.520 rs13012481 chr2:99754290 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.85 8.37 0.6 1.02e-13 Chronic sinus infection; TGCT cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg08280861 chr8:58055591 NA 0.56 6.34 0.49 3.88e-9 Developmental language disorder (linguistic errors); TGCT cis rs7172809 0.796 rs4886870 chr15:77827471 A/C cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs6964587 0.869 rs10278155 chr7:91532456 T/G cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs9902453 0.845 rs2617875 chr17:28090024 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.78 7.28 0.55 3.4e-11 Coffee consumption (cups per day); TGCT cis rs5750830 0.649 rs5750822 chr22:39826788 C/T cg11247378 chr22:39784982 NA -0.7 -9.59 -0.65 1.25e-16 Intelligence (multi-trait analysis); TGCT cis rs3096299 0.586 rs4572400 chr16:89533516 T/A cg02187348 chr16:89574699 SPG7 0.58 5.83 0.46 4.47e-8 Multiple myeloma (IgH translocation); TGCT cis rs12533831 0.654 rs2487151 chr7:150890241 C/T cg04712895 chr7:150801789 AGAP3 -0.22 -4.66 -0.39 7.93e-6 Childhood ear infection; TGCT cis rs7635838 0.927 rs13082150 chr3:11437813 T/C cg00170343 chr3:11313890 ATG7 0.65 6.23 0.49 6.56e-9 HDL cholesterol; TGCT cis rs2072438 0.503 rs1323474 chr9:123852859 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.47 0.37 1.77e-5 Rheumatoid arthritis; TGCT cis rs5769707 0.933 rs2157444 chr22:49994292 A/G cg10356904 chr22:49881777 NA -0.24 -4.89 -0.4 3.11e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1865760 0.602 rs9467662 chr6:26021327 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.8 7.57 0.56 7.45e-12 Height; TGCT cis rs12891047 1.000 rs11158693 chr14:68241261 A/G cg26938013 chr14:69015199 RAD51L1 -0.43 -4.54 -0.38 1.32e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs12701220 0.895 rs12534778 chr7:1065861 C/T cg07217954 chr7:1067459 C7orf50 0.46 4.54 0.38 1.34e-5 Bronchopulmonary dysplasia; TGCT cis rs4824093 0.544 rs73443957 chr22:50305515 T/C cg20569369 chr22:51173646 NA 0.28 4.47 0.37 1.73e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2153535 0.580 rs6597325 chr6:8461053 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10504229 0.817 rs55949560 chr8:58167603 T/C cg21724239 chr8:58056113 NA 0.34 4.64 0.38 8.88e-6 Developmental language disorder (linguistic errors); TGCT cis rs2230307 0.536 rs700533 chr1:100483822 A/G cg24955406 chr1:100503596 HIAT1 0.74 4.83 0.4 4e-6 Carotid intima media thickness; TGCT cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg11890956 chr21:40555474 PSMG1 0.8 7.66 0.57 4.53e-12 Cognitive function; TGCT cis rs9473924 0.542 rs55648125 chr6:50816718 A/G cg14470998 chr6:50812995 TFAP2B 1.32 6.51 0.5 1.65e-9 Body mass index; TGCT cis rs9811920 0.809 rs4577503 chr3:99657922 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.2 0.42 7.88e-7 Axial length; TGCT cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.85 -6.05 -0.48 1.57e-8 Gut microbiome composition (summer); TGCT cis rs42648 0.935 rs2188233 chr7:89958315 G/A cg25739043 chr7:89950458 NA -0.77 -7.39 -0.55 1.93e-11 Homocysteine levels; TGCT cis rs16957091 0.647 rs28871732 chr15:43188848 C/T cg17935677 chr15:44119062 WDR76 0.52 4.71 0.39 6.44e-6 MGMT methylation in smokers; TGCT cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg02487422 chr3:49467188 NICN1 0.54 5.2 0.42 8.11e-7 Menarche (age at onset); TGCT cis rs7216064 1.000 rs62085993 chr17:65923152 T/C cg12091567 chr17:66097778 LOC651250 -0.81 -6.15 -0.48 9.71e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9534288 0.797 rs2806922 chr13:46518059 A/G cg15192986 chr13:46630673 CPB2 -0.51 -6.91 -0.53 2.28e-10 Blood protein levels; TGCT cis rs11122272 0.766 rs2808614 chr1:231550168 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.71 6.89 0.53 2.5e-10 Hemoglobin concentration; TGCT cis rs9814567 1.000 rs2370578 chr3:134199612 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.97 -9.24 -0.64 8.89e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2299587 0.775 rs10113677 chr8:17767684 T/A cg04898035 chr8:17640624 MTUS1 -0.21 -4.5 -0.37 1.56e-5 Economic and political preferences; TGCT cis rs6121246 0.909 rs6060870 chr20:30303299 C/T cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs875971 1.000 rs2420168 chr7:65630631 C/G cg11764359 chr7:65958608 NA -0.6 -5.32 -0.43 4.63e-7 Aortic root size; TGCT cis rs12908161 1.000 rs11632465 chr15:85282045 A/T cg11189052 chr15:85197271 WDR73 0.7 5.76 0.46 6.18e-8 Schizophrenia; TGCT cis rs1153858 0.621 rs1719237 chr15:45579822 G/A cg14582100 chr15:45693742 SPATA5L1 0.47 5.2 0.42 8.07e-7 Homoarginine levels; TGCT cis rs208515 0.525 rs10944868 chr6:66687508 A/G cg07460842 chr6:66804631 NA 0.87 9.16 0.64 1.32e-15 Exhaled nitric oxide levels; TGCT cis rs4819052 0.819 rs13046807 chr21:46672286 A/G cg06618935 chr21:46677482 NA -0.37 -5.51 -0.44 1.98e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4455778 0.600 rs4478520 chr7:49079788 A/G cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs2019872 0.810 rs9892559 chr17:2067737 C/A cg24156229 chr17:1948635 NA -0.36 -4.57 -0.38 1.15e-5 Schizophrenia; TGCT cis rs8177253 0.828 rs8177259 chr3:133480388 T/C cg16414030 chr3:133502952 NA -0.61 -9.66 -0.66 8.36e-17 Iron status biomarkers; TGCT cis rs12908161 0.960 rs11633450 chr15:85307287 C/T cg12863693 chr15:85201151 NMB 0.44 4.68 0.39 7.54e-6 Schizophrenia; TGCT cis rs694739 0.595 rs11606015 chr11:64136877 C/G cg23796481 chr11:64053134 BAD;GPR137 0.64 6.62 0.51 9.49e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9814567 0.896 rs10935123 chr3:134345327 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.8 -7.29 -0.55 3.14e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7246657 0.943 rs7259968 chr19:37811854 T/C cg18154014 chr19:37997991 ZNF793 0.74 5.08 0.42 1.34e-6 Coronary artery calcification; TGCT cis rs7681440 1.000 rs7681440 chr4:90756550 C/G cg14346243 chr4:90757452 SNCA 0.53 5.16 0.42 9.54e-7 Dementia with Lewy bodies; TGCT cis rs838147 0.534 rs2638280 chr19:49209318 G/A cg05248581 chr19:49925731 PTH2 0.43 4.7 0.39 6.89e-6 Dietary macronutrient intake; TGCT cis rs7769051 1.000 rs3813347 chr6:133119778 G/A cg07930552 chr6:133119739 C6orf192 0.94 5.04 0.41 1.6e-6 Type 2 diabetes nephropathy; TGCT cis rs7926906 0.664 rs10765389 chr11:90519401 C/A cg26138821 chr11:89956704 CHORDC1 -0.43 -4.53 -0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.61 -6.11 -0.48 1.17e-8 Bipolar disorder; TGCT cis rs12497850 0.864 rs4513485 chr3:49139966 G/A cg02487422 chr3:49467188 NICN1 0.5 4.55 0.38 1.24e-5 Parkinson's disease; TGCT cis rs2072438 0.503 rs4837810 chr9:123881199 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.48 0.37 1.65e-5 Rheumatoid arthritis; TGCT cis rs7432375 0.901 rs7616204 chr3:136444589 C/T cg12473912 chr3:136751656 NA -0.36 -5.06 -0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9638182 0.778 rs3812316 chr7:73020337 C/G cg14087351 chr7:73037990 MLXIPL -0.71 -5.51 -0.44 1.95e-7 Triglycerides; TGCT cis rs7599312 0.534 rs7607363 chr2:213402705 A/G cg16329650 chr2:213403929 ERBB4 1.06 16.47 0.83 5.13e-33 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6545883 0.791 rs2600665 chr2:61405795 G/T cg15711740 chr2:61764176 XPO1 -0.54 -4.68 -0.39 7.34e-6 Tuberculosis; TGCT cis rs9926296 0.656 rs2376882 chr16:89827002 T/C cg03388025 chr16:89894329 SPIRE2 0.31 4.62 0.38 9.35e-6 Vitiligo; TGCT cis rs3008870 1.000 rs1925412 chr1:67405057 G/A cg11518657 chr1:67396239 MIER1 0.54 4.68 0.39 7.24e-6 Lymphocyte percentage of white cells; TGCT cis rs1461503 0.780 rs75981430 chr11:122842469 A/C cg27398637 chr11:122830231 C11orf63 -0.42 -5.24 -0.43 6.58e-7 Menarche (age at onset); TGCT cis rs1865760 0.713 rs1130000 chr6:25985396 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 6.94 0.53 1.97e-10 Height; TGCT cis rs8032315 1.000 rs6227 chr15:91425232 C/T cg03209642 chr15:91427605 FES 0.5 4.64 0.38 8.73e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6750047 0.585 rs336033 chr2:38263808 A/G cg07380506 chr2:38303506 CYP1B1 -0.55 -5.03 -0.41 1.69e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs11578119 0.933 rs12135326 chr1:170490570 G/A cg09767346 chr1:170501363 GORAB 0.66 5.31 0.43 4.99e-7 Male-pattern baldness; TGCT cis rs903263 0.965 rs12094426 chr1:84597131 T/A cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.69e-6 Breast cancer (male); TGCT cis rs9811920 0.609 rs10936005 chr3:99674093 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.62 7.25 0.55 3.85e-11 Axial length; TGCT trans rs2727020 0.894 rs1917328 chr11:49359606 G/A cg03929089 chr4:120376271 NA -0.65 -6.9 -0.53 2.32e-10 Coronary artery disease; TGCT trans rs7618501 1.000 rs2234391 chr3:49842625 A/G cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs55838121 chr5:266890 G/A cg22857025 chr5:266934 NA -0.33 -6.69 -0.51 6.9e-10 Breast cancer; TGCT cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg10295955 chr4:187884368 NA 0.96 14.59 0.79 1.08e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs7412746 0.611 rs4970984 chr1:150887377 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs4665809 1.000 rs6729757 chr2:26285102 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs9611565 0.729 rs203320 chr22:41913477 T/C cg03806693 chr22:41940476 POLR3H -0.96 -10.58 -0.69 4.92e-19 Vitiligo; TGCT cis rs2692947 0.832 rs2438978 chr2:96679740 G/C cg13655245 chr2:97463316 CNNM4 0.16 4.71 0.39 6.63e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs79349575 0.783 rs58591767 chr17:47026076 G/A cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs7017914 0.870 rs3098880 chr8:71938921 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs9788682 0.948 rs59683676 chr15:78833453 T/C cg24631222 chr15:78858424 CHRNA5 0.92 7.57 0.56 7.51e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs801193 0.591 rs2707839 chr7:66193084 A/G cg11764359 chr7:65958608 NA 0.59 5.09 0.42 1.31e-6 Aortic root size; TGCT cis rs7666738 0.753 rs17027308 chr4:99091088 T/A cg17366294 chr4:99064904 C4orf37 0.69 6.76 0.52 4.88e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10465746 0.725 rs1359331 chr1:84360301 C/A cg10977910 chr1:84465055 TTLL7 0.68 6.7 0.52 6.46e-10 Obesity-related traits; TGCT cis rs11578119 0.866 rs10919378 chr1:170354387 G/A cg09767346 chr1:170501363 GORAB 0.61 4.61 0.38 9.8e-6 Male-pattern baldness; TGCT cis rs72781680 0.752 rs55806536 chr2:23912697 A/G cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT cis rs9560113 0.597 rs1163644 chr13:112241223 C/T cg10483660 chr13:112241077 NA -0.36 -5.58 -0.45 1.42e-7 Menarche (age at onset); TGCT cis rs727563 0.555 rs5751136 chr22:42075581 T/A cg13695892 chr22:41940480 POLR3H 0.9 8.67 0.61 1.99e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3858526 0.642 rs10838783 chr11:5900282 T/G cg13902645 chr11:5959945 NA -0.43 -4.61 -0.38 9.96e-6 DNA methylation (variation); TGCT trans rs8073060 0.544 rs9912939 chr17:34005264 T/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9916302 0.851 rs6503502 chr17:37501855 A/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs13118159 0.872 rs4974604 chr4:1345798 T/C cg13395646 chr4:1353034 KIAA1530 -0.38 -4.65 -0.39 8.41e-6 Longevity; TGCT cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6450176 0.909 rs3776721 chr5:53292522 A/G ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs11650494 0.908 rs118099826 chr17:47447836 G/T cg08112188 chr17:47440006 ZNF652 0.97 5.04 0.41 1.62e-6 Prostate cancer; TGCT cis rs3749237 0.595 rs1050088 chr3:49570882 C/T cg03060546 chr3:49711283 APEH -0.74 -8.38 -0.6 9.96e-14 Resting heart rate; TGCT cis rs1008375 0.863 rs10003291 chr4:17600728 A/C cg16339924 chr4:17578868 LAP3 0.85 6.84 0.52 3.29e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4803468 1.000 rs3810175 chr19:41904396 C/T cg09537434 chr19:41945824 ATP5SL 0.89 10.04 0.67 9.93e-18 Height; TGCT cis rs425277 0.606 rs3128295 chr1:2068480 C/T cg24578937 chr1:2090814 PRKCZ -0.26 -6.05 -0.48 1.57e-8 Height; TGCT cis rs11676348 0.818 rs7423433 chr2:218985084 G/A cg00012203 chr2:219082015 ARPC2 -0.52 -4.99 -0.41 2e-6 Ulcerative colitis; TGCT cis rs9948 0.521 rs59648446 chr2:97351561 A/G cg01990225 chr2:97406019 LMAN2L -0.82 -4.74 -0.39 5.66e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs6495367 1.000 rs1007365 chr15:79379492 T/G cg17916960 chr15:79447300 NA 0.36 5.22 0.42 7.42e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs4819052 0.851 rs35871601 chr21:46675214 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9811920 0.609 rs793463 chr3:99620252 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.75 -0.52 5.15e-10 Axial length; TGCT cis rs13256369 0.802 rs1060107 chr8:8561399 G/T cg18904891 chr8:8559673 CLDN23 0.58 5.32 0.43 4.68e-7 Obesity-related traits; TGCT cis rs7707921 0.602 rs10514231 chr5:81307412 C/T cg15871215 chr5:81402204 ATG10 0.28 4.87 0.4 3.26e-6 Breast cancer; TGCT cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.78 8.3 0.6 1.5e-13 Age at first birth; TGCT cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.6 -5.9 -0.47 3.28e-8 Intelligence (multi-trait analysis); TGCT cis rs2839186 0.771 rs2280957 chr21:47642272 A/G cg13732083 chr21:47605072 C21orf56 -0.35 -4.54 -0.38 1.31e-5 Testicular germ cell tumor; TGCT cis rs2299587 0.554 rs2073567 chr8:17754034 G/A cg04898035 chr8:17640624 MTUS1 -0.21 -4.7 -0.39 6.74e-6 Economic and political preferences; TGCT cis rs2562456 0.761 rs35008138 chr19:21731624 A/T cg01304269 chr19:21688519 ZNF429 0.57 4.74 0.39 5.86e-6 Pain; TGCT cis rs727563 0.565 rs132774 chr22:42031953 C/G cg03806693 chr22:41940476 POLR3H -0.91 -8.88 -0.62 6.25e-15 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7727544 0.631 rs13357280 chr5:131600187 A/G cg24060327 chr5:131705240 SLC22A5 -0.54 -5.29 -0.43 5.45e-7 Blood metabolite levels; TGCT cis rs17345786 0.520 rs12638134 chr3:101334609 G/T cg12386194 chr3:101231763 SENP7 0.51 5.5 0.44 2.03e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6540559 0.546 rs74991018 chr1:210033790 T/G cg22029157 chr1:209979665 IRF6 0.79 5.78 0.46 5.6e-8 Cleft lip with or without cleft palate; TGCT cis rs11148252 0.538 rs9535879 chr13:52704624 T/A cg00495681 chr13:53174319 NA 0.57 5.87 0.47 3.78e-8 Lewy body disease; TGCT cis rs394563 0.591 rs11964335 chr6:149658101 A/T cg16235748 chr6:149772707 ZC3H12D 0.44 5.06 0.41 1.47e-6 Dupuytren's disease; TGCT cis rs2458413 0.903 rs2669448 chr8:105372324 T/G cg04554929 chr8:105342491 NA 0.5 6.4 0.5 2.95e-9 Paget's disease; TGCT cis rs10892173 0.716 rs12792357 chr11:117666595 C/T cg07621104 chr11:117668040 DSCAML1 0.51 5.4 0.44 3.27e-7 Myopia; TGCT cis rs4988958 0.584 rs12712149 chr2:103045193 A/G cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs11252926 0.563 rs10795103 chr10:451849 C/A cg13477178 chr10:375248 DIP2C -0.24 -4.44 -0.37 1.95e-5 Psychosis in Alzheimer's disease; TGCT cis rs7772486 0.790 rs1062068 chr6:146207465 A/G cg05347473 chr6:146136440 FBXO30 0.53 5.08 0.42 1.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467711 0.606 rs9393707 chr6:26362486 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs1908814 0.516 rs13281315 chr8:11794855 C/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg26818010 chr10:134567672 INPP5A -0.37 -5.02 -0.41 1.74e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11239930 0.538 rs4950355 chr1:146554249 C/T cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs7666738 0.830 rs28802909 chr4:99039410 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9916302 0.904 rs602282 chr17:37433021 C/T cg07936489 chr17:37558343 FBXL20 -0.64 -5.03 -0.41 1.68e-6 Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.779 rs7356491 chr4:120381974 C/T cg09307838 chr4:120376055 NA 0.71 6.98 0.53 1.57e-10 Corneal astigmatism; TGCT cis rs9457247 0.935 rs401260 chr6:167405888 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1448094 0.556 rs2061686 chr12:86170951 C/T cg02569458 chr12:86230093 RASSF9 -0.39 -4.58 -0.38 1.14e-5 Major depressive disorder; TGCT cis rs5769707 0.837 rs1573726 chr22:50032872 G/A cg20744362 chr22:50050164 C22orf34 0.29 4.64 0.38 8.88e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4499344 0.622 rs7246407 chr19:33061209 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.62 -5.31 -0.43 4.93e-7 Mean platelet volume; TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg07157834 chr1:205819609 PM20D1 0.49 8.61 0.61 2.77e-14 Menarche (age at onset); TGCT cis rs751728 0.717 rs3763258 chr6:33773744 A/G cg13859433 chr6:33739653 LEMD2 -0.38 -6.73 -0.52 5.64e-10 Crohn's disease; TGCT cis rs62209 0.800 rs201082 chr10:11005704 G/A cg26901096 chr10:10994189 LOC254312 0.3 4.95 0.41 2.41e-6 Alzheimer's disease (late onset); TGCT cis rs9399137 0.507 rs12663447 chr6:135317026 A/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT trans rs7613875 0.580 rs11709503 chr3:49991167 G/T cg21659725 chr3:3221576 CRBN 0.67 7.53 0.56 9.05e-12 Body mass index; TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg26338869 chr17:61819248 STRADA 0.52 4.83 0.4 3.94e-6 Prudent dietary pattern; TGCT cis rs9926296 0.656 rs2376881 chr16:89827011 C/G cg04287289 chr16:89883240 FANCA 0.68 6.85 0.52 3.13e-10 Vitiligo; TGCT cis rs4499344 0.696 rs10402929 chr19:33100245 C/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs1008375 1.000 rs1121091 chr4:17676386 A/C cg18681998 chr4:17616180 MED28 0.89 10.2 0.68 4.06e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6121246 0.609 rs4453755 chr20:30331047 G/A cg13852791 chr20:30311386 BCL2L1 0.84 8.15 0.59 3.38e-13 Mean corpuscular hemoglobin; TGCT cis rs13191362 1.000 rs13214516 chr6:163121583 A/T cg21926612 chr6:163149169 PACRG;PARK2 1.16 9.92 0.67 1.96e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2506889 0.553 rs11580264 chr1:10605796 C/A cg17425144 chr1:10567563 PEX14 0.53 7.34 0.55 2.4e-11 Breast cancer; TGCT cis rs9646954 0.542 rs4149512 chr2:101022886 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.76 0.39 5.2e-6 Intelligence (multi-trait analysis); TGCT cis rs2180341 1.000 rs2144743 chr6:127633810 A/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs7572733 0.534 rs11899188 chr2:198740121 C/T cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs1629083 0.875 rs4938490 chr11:118080977 G/A cg16594165 chr11:118135105 MPZL2 -0.33 -4.59 -0.38 1.09e-5 Lung cancer; TGCT cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg04267008 chr7:1944627 MAD1L1 -0.34 -4.6 -0.38 1.01e-5 Bipolar disorder and schizophrenia; TGCT cis rs1362404 0.648 rs1861321 chr16:51992170 A/C cg03955530 chr16:52681474 NA 0.31 4.55 0.38 1.24e-5 Gut microbiota (bacterial taxa); TGCT cis rs780096 0.526 rs780107 chr2:27684734 A/G cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT cis rs8103278 1.000 rs7252126 chr19:46302374 T/A cg14061069 chr19:46274453 DMPK -0.42 -5.81 -0.46 4.92e-8 Coronary artery disease; TGCT cis rs597539 0.652 rs604524 chr11:68629929 G/A cg21862992 chr11:68658383 NA 0.48 6.84 0.52 3.19e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs57590327 0.508 rs4622918 chr3:81965382 A/G cg07356753 chr3:81810745 GBE1 -0.74 -6.9 -0.53 2.41e-10 Extraversion; TGCT cis rs7829975 0.623 rs10092965 chr8:8373485 A/G cg15556689 chr8:8085844 FLJ10661 0.76 7.39 0.55 1.93e-11 Mood instability; TGCT cis rs7666738 0.830 rs34313689 chr4:99013689 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs548987 0.507 rs35875210 chr6:25827484 A/G cg12310025 chr6:25882481 NA -0.57 -4.61 -0.38 9.67e-6 Homocysteine levels; TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg08736216 chr1:53307985 ZYG11A 0.24 4.59 0.38 1.09e-5 Monocyte count; TGCT cis rs1215050 0.791 rs1605259 chr4:98799732 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg23131131 chr22:24373011 LOC391322 -0.81 -9.08 -0.63 2.09e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28595532 0.920 rs56322132 chr4:119742496 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4654899 0.733 rs10799678 chr1:21322785 C/T cg01072550 chr1:21505969 NA -0.55 -8.91 -0.62 5.34e-15 Superior frontal gyrus grey matter volume; TGCT cis rs6967414 0.786 rs3757482 chr7:6748927 A/G cg09896999 chr7:6746977 ZNF12 -0.57 -6.37 -0.5 3.36e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs7412746 0.524 rs58304714 chr1:150831561 T/A cg09365446 chr1:150670422 GOLPH3L 0.35 4.98 0.41 2.11e-6 Melanoma; TGCT cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg10862848 chr6:42927986 GNMT -0.38 -4.72 -0.39 6.35e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7113874 0.569 rs10840077 chr11:8601210 A/T cg14521421 chr11:8862019 ST5 -0.28 -4.44 -0.37 1.96e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs1182436 1 rs1182436 chr7:157027753 T/C cg05182265 chr7:156933206 UBE3C 0.27 4.49 0.37 1.59e-5 Type 2 diabetes; TGCT cis rs12134133 1.000 rs1583090 chr1:207435783 T/C cg02152968 chr1:207494213 CD55 0.63 4.88 0.4 3.22e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs10254284 1.000 rs10254284 chr7:28167391 A/T cg23620719 chr7:28220237 JAZF1 -0.56 -4.97 -0.41 2.21e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg10047753 chr17:41438598 NA 0.74 6.98 0.53 1.61e-10 Menopause (age at onset); TGCT cis rs7772486 0.875 rs2748502 chr6:146298239 A/G cg23711669 chr6:146136114 FBXO30 0.84 8.85 0.62 7.33e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs79349575 0.783 rs17708633 chr17:47011620 C/G cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs6952808 0.609 rs6970033 chr7:1948087 G/A cg04267008 chr7:1944627 MAD1L1 -0.37 -4.83 -0.4 3.94e-6 Bipolar disorder and schizophrenia; TGCT cis rs4906332 0.966 rs34372508 chr14:103977515 G/A cg26031613 chr14:104095156 KLC1 -0.54 -4.66 -0.39 8.15e-6 Coronary artery disease; TGCT cis rs7246657 0.722 rs2927742 chr19:38133618 T/C cg18154014 chr19:37997991 ZNF793 -0.68 -4.59 -0.38 1.09e-5 Coronary artery calcification; TGCT cis rs9952991 0.566 rs34846641 chr18:12875975 A/G cg23598886 chr18:12777645 NA -0.55 -4.86 -0.4 3.43e-6 Inflammatory skin disease; TGCT cis rs7104764 0.879 rs6598070 chr11:225466 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 10.53 0.69 6.69e-19 Menarche (age at onset); TGCT cis rs2933343 0.649 rs789219 chr3:128592520 G/A cg11901034 chr3:128598214 ACAD9 -0.65 -6.02 -0.48 1.83e-8 IgG glycosylation; TGCT cis rs6582630 0.537 rs3942440 chr12:38459672 A/G cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9650657 0.645 rs4841408 chr8:10516336 A/G cg27411982 chr8:10470053 RP1L1 -0.23 -4.98 -0.41 2.07e-6 Neuroticism; TGCT cis rs7647973 0.626 rs62262722 chr3:49769419 G/C cg05785598 chr3:49045655 WDR6 -0.44 -5.19 -0.42 8.17e-7 Menarche (age at onset); TGCT cis rs9322193 0.884 rs11155669 chr6:149954637 T/C cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs858239 0.600 rs28646184 chr7:23139595 T/C cg05602783 chr7:23145260 KLHL7 -0.68 -5.76 -0.46 6.17e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs924607 0.900 rs1697950 chr5:616890 G/A cg04476341 chr5:669733 TPPP -0.26 -4.57 -0.38 1.14e-5 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs4851254 0.618 rs13001130 chr2:100668699 G/A cg07810366 chr2:100720526 AFF3 -0.49 -5.04 -0.41 1.61e-6 Intelligence (multi-trait analysis); TGCT cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg11494091 chr17:61959527 GH2 0.42 7.28 0.55 3.36e-11 Height; TGCT cis rs6589563 0.737 rs61905086 chr11:116614863 T/C cg26530557 chr11:116448269 NA -0.27 -4.47 -0.37 1.73e-5 Eosinophil counts; TGCT cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg11279151 chr3:101281821 RG9MTD1 -0.42 -8.66 -0.61 2.07e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs1483890 0.723 rs13075664 chr3:69411365 G/A cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs7666738 0.830 rs62318906 chr4:99037110 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11085466 0.948 rs76881507 chr19:21762189 A/T cg02997983 chr19:21646781 NA -0.63 -4.53 -0.38 1.35e-5 Colorectal or endometrial cancer; TGCT cis rs12911832 1.000 rs12911961 chr15:58985867 C/T cg05156742 chr15:59063176 FAM63B 0.54 5.11 0.42 1.19e-6 Schizophrenia; TGCT cis rs9457247 0.756 rs1811123 chr6:167403443 T/C cg23791538 chr6:167370224 RNASET2 -0.46 -4.45 -0.37 1.87e-5 Crohn's disease; TGCT cis rs1371867 0.846 rs2439460 chr8:101312665 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT trans rs11992162 0.597 rs7011924 chr8:11780593 G/A cg15556689 chr8:8085844 FLJ10661 -0.79 -6.77 -0.52 4.69e-10 Monocyte count; TGCT cis rs7772486 0.875 rs2180192 chr6:146322284 T/C cg05347473 chr6:146136440 FBXO30 0.53 5.01 0.41 1.81e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.541 rs6923558 chr6:8461467 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10782582 0.609 rs5745325 chr1:76269460 G/A cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs9296092 0.517 rs7743178 chr6:33470462 G/A cg13560919 chr6:33536144 NA -0.22 -4.49 -0.37 1.6e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs17221829 0.703 rs10830347 chr11:89415165 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 2e-5 Anxiety in major depressive disorder; TGCT cis rs9611565 0.729 rs202654 chr22:41841034 G/A cg06634786 chr22:41940651 POLR3H 0.81 7.71 0.57 3.43e-12 Vitiligo; TGCT cis rs4746818 1.000 rs7909631 chr10:70918676 C/T cg11621586 chr10:70884670 VPS26A 1.23 10.93 0.7 6.87e-20 Left atrial antero-posterior diameter; TGCT cis rs9905704 0.647 rs6503892 chr17:57067086 G/A cg05425664 chr17:57184151 TRIM37 -0.56 -4.44 -0.37 2e-5 Testicular germ cell tumor; TGCT cis rs7666738 0.830 rs13328042 chr4:99055406 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7914558 0.933 rs2066323 chr10:104871361 A/G cg04362960 chr10:104952993 NT5C2 0.63 5.64 0.45 1.07e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs45430 1.000 rs45430 chr21:42746081 C/T cg22778903 chr21:42741698 MX2 0.31 5.23 0.43 6.92e-7 Melanoma; TGCT cis rs6570726 0.791 rs13202312 chr6:145913093 T/G cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs910316 0.967 rs12147532 chr14:75651858 T/G cg23033748 chr14:75592666 NEK9 -0.27 -4.47 -0.37 1.73e-5 Height; TGCT cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg09177884 chr7:1199841 ZFAND2A -0.51 -4.9 -0.4 2.98e-6 Longevity;Endometriosis; TGCT cis rs7621025 0.664 rs6439657 chr3:136494639 C/T cg15507776 chr3:136538369 TMEM22 -0.5 -4.55 -0.38 1.24e-5 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs4803468 1.000 rs11880539 chr19:41918949 A/C cg09537434 chr19:41945824 ATP5SL 0.88 10.4 0.68 1.32e-18 Height; TGCT cis rs4689592 0.523 rs6446565 chr4:7074027 A/G cg02503808 chr4:7069936 GRPEL1 1.01 9.65 0.66 8.71e-17 Monocyte percentage of white cells; TGCT cis rs1401999 0.966 rs2139560 chr3:183653869 A/G cg01324343 chr3:183735012 ABCC5 0.85 11.38 0.71 5.52e-21 Anterior chamber depth; TGCT cis rs3820068 0.554 rs60233444 chr1:15921330 A/C cg05660106 chr1:15850417 CASP9 0.84 8.27 0.6 1.8e-13 Systolic blood pressure; TGCT cis rs7666738 0.783 rs10028584 chr4:98962404 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg11502198 chr6:26597334 ABT1 0.51 4.78 0.39 4.82e-6 Intelligence (multi-trait analysis); TGCT cis rs1372520 0.684 rs2583968 chr4:90745395 C/G cg15133208 chr4:90757351 SNCA -0.49 -5.69 -0.45 8.67e-8 Neuroticism; TGCT cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs9910055 0.529 rs850851 chr17:42177674 C/T cg19774624 chr17:42201019 HDAC5 0.69 6.36 0.5 3.46e-9 Total body bone mineral density; TGCT cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg06481639 chr22:41940642 POLR3H -0.74 -6.55 -0.51 1.41e-9 Vitiligo; TGCT cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg27286337 chr10:134555280 INPP5A 0.45 5.32 0.43 4.64e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs861020 0.883 rs680331 chr1:209959872 G/A cg05527609 chr1:210001259 C1orf107 0.91 7.99 0.58 7.87e-13 Orofacial clefts; TGCT cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg08280861 chr8:58055591 NA 0.38 4.51 0.38 1.48e-5 Developmental language disorder (linguistic errors); TGCT trans rs7613875 0.620 rs2526747 chr3:50082914 C/G cg21659725 chr3:3221576 CRBN 0.65 7.16 0.54 6.39e-11 Body mass index; TGCT cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg11890956 chr21:40555474 PSMG1 1.12 11.44 0.72 3.95e-21 Cognitive function; TGCT cis rs7769051 0.711 rs9493437 chr6:133088405 A/T cg07930552 chr6:133119739 C6orf192 0.87 4.55 0.38 1.27e-5 Type 2 diabetes nephropathy; TGCT cis rs61990749 0.544 rs8003979 chr14:78211290 C/T cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT trans rs525455 1.000 rs525535 chr10:13103316 G/A cg21721093 chr17:8906386 NA 0.64 6.7 0.52 6.38e-10 Platelet aggregation; TGCT cis rs6910741 0.592 rs9379800 chr6:25889099 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 5.3 0.43 5.02e-7 Blood pressure; TGCT cis rs1062177 0.855 rs62395861 chr5:151269270 A/G cg12924095 chr5:151150029 G3BP1 0.37 5.04 0.41 1.59e-6 Preschool internalizing problems; TGCT cis rs4851266 0.898 rs12615145 chr2:100853116 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.21 -0.42 7.59e-7 Educational attainment; TGCT cis rs17401966 0.558 rs6541090 chr1:10402842 A/G cg19773385 chr1:10388646 KIF1B -0.22 -5.27 -0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs7582180 0.764 rs12999779 chr2:100924321 T/G cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.586 rs1007708 chr20:25190959 C/T cg16686733 chr20:25566563 NINL 0.55 5.49 0.44 2.17e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1476679 0.927 rs2405442 chr7:99971313 T/C cg13334819 chr7:99746414 C7orf59 0.74 6.38 0.5 3.23e-9 Alzheimer's disease (late onset); TGCT cis rs7193541 0.694 rs3896277 chr16:74480694 A/T cg01733217 chr16:74700730 RFWD3 0.63 5.8 0.46 5.25e-8 Multiple myeloma; TGCT cis rs6669072 0.647 rs814543 chr1:91241709 C/T cg08895590 chr1:91227319 NA 0.34 4.51 0.38 1.5e-5 Cognitive function; TGCT cis rs748404 0.660 rs690446 chr15:43761264 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.77 0.39 5.05e-6 Lung cancer; TGCT cis rs13064411 0.660 rs1872747 chr3:113175785 T/A cg18753928 chr3:113234510 CCDC52 -0.68 -4.74 -0.39 5.8e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs11779988 0.571 rs208053 chr8:17825327 G/A cg01800426 chr8:17659068 MTUS1 -0.66 -4.94 -0.41 2.42e-6 Breast cancer; TGCT cis rs477895 0.838 rs11607007 chr11:64007976 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.84 7.07 0.54 1.02e-10 Mean platelet volume; TGCT cis rs7027203 0.964 rs6479512 chr9:96556985 G/A cg14396892 chr9:96623032 NA 0.25 4.78 0.39 4.79e-6 DNA methylation (variation); TGCT cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg15691649 chr6:25882328 NA -0.38 -5.03 -0.41 1.65e-6 Blood metabolite levels; TGCT cis rs6471915 0.502 rs12548415 chr8:61968256 G/A cg05142030 chr8:62551054 ASPH 0.24 4.51 0.38 1.48e-5 Prudent dietary pattern; TGCT cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2806561 0.765 rs623988 chr1:23519477 C/T cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs6460942 0.915 rs62448621 chr7:12459941 G/A cg06484146 chr7:12443880 VWDE -0.57 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT cis rs5769707 0.967 rs5770585 chr22:50007874 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.61 0.38 1e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7681440 0.874 rs1372524 chr4:90776045 A/G cg20003494 chr4:90757398 SNCA -0.56 -5.35 -0.43 4.11e-7 Dementia with Lewy bodies; TGCT cis rs2046867 0.818 rs62249860 chr3:72866073 T/G cg25664220 chr3:72788482 NA -0.56 -7.04 -0.53 1.16e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7772486 0.688 rs1884364 chr6:146337817 C/G cg05347473 chr6:146136440 FBXO30 0.56 5.31 0.43 4.9e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1475911 0.708 rs56185023 chr21:43521538 T/C cg19766460 chr21:43528205 UMODL1;C21orf128 0.64 9.26 0.64 7.72e-16 IgG glycosylation; TGCT cis rs2180341 0.782 rs6912750 chr6:127723081 A/T cg24812749 chr6:127587940 RNF146 0.65 5.19 0.42 8.37e-7 Breast cancer; TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg08859206 chr1:53392774 SCP2 0.39 6.07 0.48 1.41e-8 Monocyte count; TGCT cis rs736408 1.000 rs736408 chr3:52835354 C/T cg18404041 chr3:52824283 ITIH1 -0.21 -4.45 -0.37 1.93e-5 Bipolar disorder; TGCT cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg13342137 chr4:2252803 MXD4 0.17 4.46 0.37 1.84e-5 Obesity-related traits; TGCT cis rs17221829 0.733 rs35757457 chr11:89358250 T/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs6740322 0.895 rs6744746 chr2:43555805 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.39 6.65 0.51 8.25e-10 Coronary artery disease; TGCT cis rs1055129 0.537 rs1135640 chr17:73949540 C/G cg10935138 chr17:73851978 WBP2 -0.51 -4.58 -0.38 1.1e-5 White matter hyperintensity burden; TGCT cis rs263156 0.903 rs263115 chr6:142885777 T/C cg18419694 chr6:143832440 FUCA2 -0.38 -4.53 -0.38 1.36e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs7666738 0.830 rs7679961 chr4:99000202 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9486715 0.867 rs4839687 chr6:96951732 C/A cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs6952808 1.000 rs6954673 chr7:1886937 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.62 -0.45 1.21e-7 Bipolar disorder and schizophrenia; TGCT cis rs2839186 0.500 rs13049893 chr21:47707054 C/T cg09417038 chr21:47716443 C21orf57 -0.32 -4.83 -0.4 3.95e-6 Testicular germ cell tumor; TGCT cis rs6546537 0.550 rs6546531 chr2:69779963 C/A cg10773587 chr2:69614142 GFPT1 -0.65 -5.94 -0.47 2.7e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs60843830 1.000 rs62114505 chr2:242426 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.7 0.57 3.78e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg11890956 chr21:40555474 PSMG1 -0.73 -7.15 -0.54 6.65e-11 Menarche (age at onset); TGCT cis rs4499344 0.535 rs7260509 chr19:33121595 G/A cg26639809 chr19:33781782 NA 0.24 5.11 0.42 1.18e-6 Mean platelet volume; TGCT cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg04352962 chr1:209979756 IRF6 0.61 4.67 0.39 7.72e-6 Cleft lip with or without cleft palate; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg09033563 chr22:24373618 LOC391322 -0.46 -4.49 -0.37 1.61e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7027203 1.000 rs7027203 chr9:96562563 A/C cg13679303 chr9:96623674 NA 0.65 9.81 0.66 3.61e-17 DNA methylation (variation); TGCT cis rs9807989 0.839 rs6749114 chr2:102967587 A/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs1552244 0.882 rs17081288 chr3:10042113 A/G cg00149659 chr3:10157352 C3orf10 0.78 4.99 0.41 2.04e-6 Alzheimer's disease; TGCT cis rs7336332 0.569 rs7988412 chr13:28000282 C/T cg22138327 chr13:27999177 GTF3A 0.9 7.49 0.56 1.12e-11 Weight; TGCT cis rs903263 0.932 rs1521518 chr1:84601048 T/C cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.73e-6 Breast cancer (male); TGCT cis rs1532993 0.518 rs4330355 chr4:98638317 C/T cg05340658 chr4:99064831 C4orf37 0.42 4.82 0.4 4.03e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6912958 0.703 rs9359748 chr6:88095500 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.61 6.04 0.48 1.66e-8 Monocyte percentage of white cells; TGCT cis rs7267979 1.000 rs6107046 chr20:25442049 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs478304 0.651 rs11604462 chr11:65551648 G/A cg27068330 chr11:65405492 SIPA1 -0.95 -9.42 -0.65 3.19e-16 Acne (severe); TGCT cis rs713587 0.520 rs522806 chr2:25316584 C/A cg01884057 chr2:25150051 NA -0.26 -4.82 -0.4 4.04e-6 Body mass index in non-asthmatics; TGCT cis rs765787 0.530 rs2413786 chr15:45525394 C/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.75e-7 Uric acid levels; TGCT cis rs2075165 0.901 rs10908492 chr1:156224795 C/T cg20302342 chr1:156215951 PAQR6 0.39 5.67 0.45 9.49e-8 Tonsillectomy; TGCT cis rs6952808 0.594 rs3778964 chr7:2138109 C/T cg04267008 chr7:1944627 MAD1L1 -0.36 -4.82 -0.4 4.05e-6 Bipolar disorder and schizophrenia; TGCT cis rs1568889 1.000 rs1568889 chr11:28009463 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.97 8.72 0.62 1.51e-14 Bipolar disorder; TGCT cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg20607798 chr8:58055168 NA 0.67 5.62 0.45 1.22e-7 Developmental language disorder (linguistic errors); TGCT trans rs1974653 0.631 rs41281423 chr22:20097730 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.65 -0.57 4.76e-12 Schizophrenia; TGCT cis rs35146811 0.695 rs858509 chr7:99821470 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs2033711 0.936 rs3794968 chr19:58986799 G/C cg13877915 chr19:58951672 ZNF132 0.81 8.73 0.62 1.43e-14 Uric acid clearance; TGCT cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.73e-7 Menopause (age at onset); TGCT cis rs4727027 0.704 rs12535154 chr7:148895304 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.45 0.37 1.9e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6988636 1.000 rs13261100 chr8:124190312 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs8033133 0.560 rs1549478 chr15:25332200 T/C cg14481604 chr15:25334117 SNORD116-22 -0.23 -4.84 -0.4 3.82e-6 Blood osmolality (transformed sodium); TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg09033563 chr22:24373618 LOC391322 -0.47 -4.64 -0.38 8.83e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13256369 0.851 rs11249890 chr8:8565245 G/T cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs7674212 0.541 rs4699051 chr4:104114394 T/C cg16532752 chr4:104119610 CENPE -0.61 -5.67 -0.45 9.45e-8 Type 2 diabetes; TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs7973719 1.000 rs12828421 chr12:7335217 C/T cg07052231 chr12:7363540 PEX5 -0.33 -4.93 -0.4 2.61e-6 IgG glycosylation; TGCT cis rs3733606 0.503 rs11734132 chr4:6891519 C/G cg18375902 chr4:7764949 AFAP1;LOC84740 -0.23 -4.62 -0.38 9.37e-6 Platelet count; TGCT cis rs1008375 1.000 rs7694020 chr4:17682597 C/T cg18681998 chr4:17616180 MED28 0.95 11.38 0.71 5.45e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs16986825 0.607 rs5762852 chr22:29242473 T/C cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Pancreatic cancer; TGCT cis rs7914558 0.933 rs12763665 chr10:104653717 G/A cg15744005 chr10:104629667 AS3MT -0.41 -5.09 -0.42 1.29e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6089829 0.926 rs7273917 chr20:61665975 G/A cg18188782 chr20:61659543 NA 0.46 5.5 0.44 2.03e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs9638182 0.667 rs33951980 chr7:73029437 C/T cg14087351 chr7:73037990 MLXIPL -0.74 -5.15 -0.42 9.73e-7 Triglycerides; TGCT cis rs2836974 0.897 rs2836944 chr21:40593539 G/A cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.3e-9 Cognitive function; TGCT cis rs3820068 0.532 rs1547034 chr1:15919049 T/A cg05660106 chr1:15850417 CASP9 0.86 8.84 0.62 8.07e-15 Systolic blood pressure; TGCT cis rs2456568 0.548 rs10466334 chr11:93663512 A/G cg26875233 chr11:93583750 C11orf90 -0.41 -4.97 -0.41 2.14e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3087591 0.960 rs1013947 chr17:29530362 C/T cg24425628 chr17:29625626 OMG;NF1 0.47 7.35 0.55 2.32e-11 Hip circumference; TGCT cis rs79057730 0.599 rs112891948 chr7:816059 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.3 0.43 5.08e-7 Initial pursuit acceleration; TGCT cis rs2012796 0.956 rs56161464 chr14:81814749 A/T cg02996355 chr14:81879375 NA 0.5 4.82 0.4 4.2e-6 Night sleep phenotypes; TGCT cis rs6988636 1.000 rs28513831 chr8:124189208 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs13064411 0.735 rs6438157 chr3:113207316 G/T cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs17712049 1.000 rs62447152 chr7:48200018 A/G cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs908922 0.676 rs11205031 chr1:152527662 C/T cg20991723 chr1:152506922 NA 0.44 5.96 0.47 2.38e-8 Hair morphology; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg18538332 chr22:24372958 LOC391322 0.89 7.91 0.58 1.21e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs4629710 0.534 rs6916881 chr6:131565153 C/T cg12606694 chr6:131520996 AKAP7 0.4 4.64 0.38 8.58e-6 Multiple myeloma (IgH translocation); TGCT cis rs2370759 0.891 rs77706860 chr10:32628537 C/T cg01819863 chr10:32635814 EPC1 1.05 6.73 0.52 5.68e-10 Sexual dysfunction (female); TGCT cis rs12368653 0.701 rs238517 chr12:58117737 T/G cg12615879 chr12:58013172 SLC26A10 0.51 6.39 0.5 3.05e-9 Multiple sclerosis; TGCT cis rs478304 0.651 rs11532071 chr11:65500198 C/A cg17480646 chr11:65405466 SIPA1 -0.57 -6.95 -0.53 1.84e-10 Acne (severe); TGCT cis rs17401966 0.867 rs12403443 chr1:10423988 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.61 -0.38 9.77e-6 Hepatocellular carcinoma; TGCT trans rs6089829 0.962 rs2872543 chr20:61665017 G/A cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.91 -6.62 -0.51 9.5e-10 Gut microbiome composition (summer); TGCT cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg24675658 chr1:53192096 ZYG11B -0.75 -8.61 -0.61 2.72e-14 Monocyte count; TGCT cis rs17268829 0.775 rs11770656 chr7:94077554 T/G cg06439941 chr7:93550756 GNG11 -0.24 -4.47 -0.37 1.74e-5 Breast cancer; TGCT cis rs2115630 0.691 rs8040066 chr15:85176465 G/C cg11189052 chr15:85197271 WDR73 -0.72 -7.12 -0.54 7.59e-11 P wave terminal force; TGCT trans rs9388451 0.874 rs7739566 chr6:126094757 A/T cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.38 -0.6 9.89e-14 Brugada syndrome; TGCT cis rs7267979 0.764 rs2474767 chr20:25246733 T/C cg03522245 chr20:25566470 NINL 0.52 5.4 0.44 3.22e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg05368731 chr17:41323189 NBR1 1.16 13.24 0.77 1.79e-25 Menopause (age at onset); TGCT cis rs3862030 0.503 rs6584506 chr10:104254428 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs4389656 0.806 rs71600298 chr5:6763290 T/A cg12187999 chr5:6845652 NA -0.33 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs881375 0.715 rs10818482 chr9:123648085 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.5 -5.42 -0.44 3.05e-7 Rheumatoid arthritis; TGCT cis rs11648796 0.757 rs3809665 chr16:764520 G/C cg07343612 chr16:622815 PIGQ -0.34 -4.93 -0.41 2.54e-6 Height; TGCT cis rs6998277 1.000 rs34217554 chr8:103646352 T/C cg10187029 chr8:103597600 NA 0.48 6.26 0.49 5.81e-9 Migraine; TGCT cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.73e-7 Menopause (age at onset); TGCT trans rs2469997 1.000 rs2470012 chr8:120360488 T/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs9467773 1.000 rs9393732 chr6:26530898 G/A cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.790 rs9376971 chr6:146259505 C/T cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs1814175 0.817 rs7932683 chr11:49983640 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs6121246 0.909 rs2376992 chr20:30263418 T/C cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs2235642 0.750 rs1894649 chr16:1657284 C/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.29 -4.93 -0.4 2.6e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs28522896 chr4:99008243 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1023500 0.551 rs2859438 chr22:42466980 A/T cg05082376 chr22:42548792 NA -0.23 -5.43 -0.44 2.83e-7 Schizophrenia; TGCT cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg03188948 chr7:1209495 NA 0.63 5.71 0.46 7.71e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg06481639 chr22:41940642 POLR3H -0.76 -7.05 -0.54 1.08e-10 Vitiligo; TGCT cis rs12477438 0.798 rs13393860 chr2:99590397 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs2905347 0.895 rs2961281 chr7:22640292 T/G cg26061582 chr7:22766209 IL6 -0.4 -4.49 -0.37 1.63e-5 Major depression and alcohol dependence; TGCT cis rs10479542 0.721 rs6894113 chr5:178974789 G/C cg19626725 chr5:178986131 RUFY1 0.46 6.02 0.48 1.87e-8 Lung cancer; TGCT cis rs9650657 0.615 rs4840519 chr8:10693113 T/C cg16664915 chr8:10907788 XKR6 -0.29 -4.59 -0.38 1.09e-5 Neuroticism; TGCT cis rs9814567 1.000 rs13081688 chr3:134259954 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9534288 0.699 rs9534321 chr13:46669032 A/G cg15192986 chr13:46630673 CPB2 -0.5 -5.94 -0.47 2.7e-8 Blood protein levels; TGCT cis rs775227 0.574 rs66866534 chr3:113147315 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.12 -0.42 1.12e-6 Dental caries; TGCT cis rs67311347 0.524 rs7649168 chr3:40356158 T/C cg13683864 chr3:40499215 RPL14 -0.84 -7.85 -0.58 1.71e-12 Renal cell carcinoma; TGCT cis rs910316 0.967 rs175479 chr14:75561871 A/C cg23033748 chr14:75592666 NEK9 -0.28 -4.76 -0.39 5.27e-6 Height; TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg08736216 chr1:53307985 ZYG11A -0.29 -5.7 -0.46 8.08e-8 Monocyte count; TGCT cis rs2153535 0.580 rs4960413 chr6:8438466 C/T cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs6912958 0.781 rs9444519 chr6:88290398 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs1577917 0.958 rs10944136 chr6:86448499 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.4 -0.44 3.28e-7 Response to antipsychotic treatment; TGCT cis rs17741873 0.779 rs3812634 chr10:75594486 C/T cg07699608 chr10:75541558 CHCHD1 0.72 5.15 0.42 1.02e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs910316 0.967 rs10142770 chr14:75525449 G/A cg08847533 chr14:75593920 NEK9 0.95 10.36 0.68 1.73e-18 Height; TGCT trans rs17780086 0.527 rs72827712 chr17:30538600 A/G cg20587970 chr11:113659929 NA -0.89 -7.15 -0.54 6.46e-11 Height; TGCT cis rs9486719 1.000 rs34209750 chr6:96882215 G/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs1878931 0.501 rs9635563 chr16:3416940 A/G cg05754148 chr16:3507555 NAT15 -0.33 -4.46 -0.37 1.82e-5 Body mass index (adult); TGCT cis rs1552244 0.554 rs2272121 chr3:10047680 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs4722585 0.764 rs4259314 chr7:26182214 A/G cg07876897 chr7:26191696 NFE2L3 -0.39 -5.73 -0.46 7.32e-8 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs2204008 0.775 rs2387809 chr12:38363338 T/A cg13010199 chr12:38710504 ALG10B 0.59 4.58 0.38 1.14e-5 Bladder cancer; TGCT trans rs561341 0.883 rs4795661 chr17:30201774 T/A cg20587970 chr11:113659929 NA 0.8 9.45 0.65 2.65e-16 Hip circumference adjusted for BMI; TGCT trans rs12599106 0.629 rs1391904 chr16:34548934 C/T cg01516881 chr6:292596 DUSP22 -0.72 -7.58 -0.56 6.97e-12 Menopause (age at onset); TGCT cis rs3733585 0.648 rs7378305 chr4:9954893 C/T cg11266682 chr4:10021025 SLC2A9 -0.59 -7.76 -0.57 2.73e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg04025307 chr7:1156635 C7orf50 0.24 5.59 0.45 1.39e-7 Longevity;Endometriosis; TGCT cis rs7949030 0.620 rs2428551 chr11:62329758 T/A cg22862634 chr11:62369728 EML3;MTA2 0.69 9.06 0.63 2.33e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs644799 0.932 rs572015 chr11:95637416 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.75 7.9 0.58 1.28e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6754311 0.551 rs9287442 chr2:136522710 A/G cg07169764 chr2:136633963 MCM6 -0.7 -6.26 -0.49 5.75e-9 Mosquito bite size; TGCT cis rs7772486 0.875 rs9403770 chr6:146423334 C/T cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs12134245 0.874 rs17501937 chr1:92021705 C/T cg25838465 chr1:92012736 NA 0.31 5.16 0.42 9.72e-7 Breast cancer; TGCT trans rs1814175 0.527 rs7128827 chr11:49665644 C/T cg11707556 chr5:10655725 ANKRD33B 0.42 8.44 0.6 7.13e-14 Height; TGCT cis rs1580019 0.587 rs7804457 chr7:32557981 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.11 14.04 0.78 2.14e-27 Cognitive ability; TGCT cis rs2115630 1.000 rs11073730 chr15:85354596 C/T cg11189052 chr15:85197271 WDR73 -0.63 -6.04 -0.48 1.67e-8 P wave terminal force; TGCT cis rs7412746 0.658 rs4537557 chr1:150734436 A/G cg09365446 chr1:150670422 GOLPH3L 0.35 5.08 0.42 1.33e-6 Melanoma; TGCT cis rs4478858 0.698 rs10914370 chr1:31854955 T/C cg07478791 chr1:31886160 SERINC2 -0.49 -4.71 -0.39 6.45e-6 Alcohol dependence; TGCT cis rs12460587 0.587 rs10415150 chr19:52604625 C/G cg13540795 chr19:52551618 ZNF432 -0.45 -4.8 -0.4 4.49e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs769267 0.930 rs10402451 chr19:19608537 A/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs514406 0.584 rs7524702 chr1:53197830 G/A cg25767906 chr1:53392781 SCP2 0.44 4.79 0.39 4.72e-6 Monocyte count; TGCT cis rs8020441 0.632 rs6572688 chr14:51165441 A/G cg04730355 chr14:51134070 SAV1 0.74 6.11 0.48 1.18e-8 Cognitive performance; TGCT cis rs6754311 0.731 rs12988076 chr2:136569848 C/A cg07169764 chr2:136633963 MCM6 -0.61 -5.61 -0.45 1.25e-7 Mosquito bite size; TGCT cis rs2637266 1.000 rs12251568 chr10:78345667 C/T cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT cis rs9549367 0.789 rs8001506 chr13:113867153 A/C cg18105134 chr13:113819100 PROZ -0.37 -6.34 -0.49 3.95e-9 Platelet distribution width; TGCT cis rs1577917 0.917 rs35283633 chr6:86690787 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs9831754 0.906 rs2089934 chr3:78382448 T/C cg06138941 chr3:78371609 NA -0.5 -5.16 -0.42 9.33e-7 Calcium levels; TGCT cis rs7208859 0.673 rs9909497 chr17:29173228 C/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4721295 0.573 rs3779000 chr7:2181628 G/A cg04267008 chr7:1944627 MAD1L1 -0.34 -4.43 -0.37 2.01e-5 Schizophrenia, schizoaffective disorder or bipolar disorder; TGCT cis rs17030434 0.749 rs1125228 chr4:154769052 C/T cg14289246 chr4:154710475 SFRP2 -0.91 -7.45 -0.56 1.4e-11 Electrocardiographic conduction measures; TGCT cis rs6570726 1.000 rs404229 chr6:145868200 G/A cg23711669 chr6:146136114 FBXO30 0.71 6.66 0.51 7.78e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3740393 0.562 rs4147155 chr10:104536771 G/A cg05855489 chr10:104503620 C10orf26 0.78 6.57 0.51 1.25e-9 Microalbuminuria; TGCT cis rs6674176 0.628 rs2301993 chr1:44426025 G/A cg13606994 chr1:44402422 ARTN -0.46 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs3772130 0.923 rs7649092 chr3:121561950 C/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs2463822 0.858 rs2513077 chr11:62105925 A/G cg06239285 chr11:62104954 ASRGL1 -0.9 -6.54 -0.51 1.42e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6684514 1.000 rs12134983 chr1:156290409 T/C cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2980439 0.525 rs2945238 chr8:8170136 A/C cg15556689 chr8:8085844 FLJ10661 0.77 7.07 0.54 1e-10 Neuroticism; TGCT cis rs7666738 0.830 rs28444709 chr4:99028496 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1395 0.925 rs1659701 chr2:27414877 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.49 -6.52 -0.51 1.61e-9 Blood metabolite levels; TGCT cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Cannabis dependence symptom count; TGCT cis rs36051895 0.559 rs7858422 chr9:5209797 G/T cg02405213 chr9:5042618 JAK2 -0.66 -8.17 -0.59 2.96e-13 Pediatric autoimmune diseases; TGCT cis rs12575480 0.709 rs7107076 chr11:2094303 C/T cg15541987 chr11:2077307 NA -0.37 -4.47 -0.37 1.71e-5 Pursuit maintenance gain; TGCT cis rs2204008 0.537 rs11170128 chr12:38006632 G/A cg13010199 chr12:38710504 ALG10B 0.64 5.08 0.42 1.33e-6 Bladder cancer; TGCT cis rs1857353 1.000 rs74089237 chr1:75888085 G/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg03609598 chr5:56110824 MAP3K1 -0.56 -4.57 -0.38 1.14e-5 Initial pursuit acceleration; TGCT cis rs113084984 0.718 rs4669744 chr2:11681568 T/C cg25804072 chr2:10829725 NOL10 0.54 4.51 0.38 1.47e-5 Breast cancer; TGCT cis rs6912958 0.678 rs9450744 chr6:88280529 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs9653442 0.527 rs10185059 chr2:100790172 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.4 -0.44 3.2e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs8072100 0.935 rs12943464 chr17:45690351 A/T cg08085267 chr17:45401833 C17orf57 0.43 4.64 0.38 8.8e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2120019 0.938 rs8036573 chr15:75308690 C/T cg17294928 chr15:75287854 SCAMP5 -0.86 -6.7 -0.52 6.39e-10 Blood trace element (Zn levels); TGCT cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs1862618 0.671 rs2591966 chr5:56233688 T/G cg12311346 chr5:56204834 C5orf35 0.53 5.53 0.44 1.79e-7 Initial pursuit acceleration; TGCT cis rs10465746 0.780 rs7529293 chr1:84331981 A/G cg10977910 chr1:84465055 TTLL7 0.66 6.65 0.51 8.38e-10 Obesity-related traits; TGCT cis rs916888 0.821 rs199513 chr17:44856932 A/G cg17911788 chr17:44343683 NA 0.53 5.79 0.46 5.5e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6547741 0.775 rs11692692 chr2:27861707 G/A cg27432699 chr2:27873401 GPN1 -0.24 -6.05 -0.48 1.57e-8 Oral cavity cancer; TGCT cis rs769267 0.930 rs10419912 chr19:19597055 A/G cg03709012 chr19:19516395 GATAD2A -0.75 -6.2 -0.49 7.59e-9 Tonsillectomy; TGCT cis rs12220238 1.000 rs10824105 chr10:75952881 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg24846343 chr22:24311635 DDTL 0.22 5.68 0.45 9.16e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs986417 0.901 rs713449 chr14:61029084 C/G cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs2832191 0.716 rs2692625 chr21:30446360 C/G cg24692254 chr21:30365293 RNF160 0.98 11.36 0.71 6.16e-21 Dental caries; TGCT cis rs9644630 0.930 rs6586840 chr8:19365832 C/T cg01280390 chr8:19363452 CSGALNACT1 -0.27 -4.68 -0.39 7.47e-6 Oropharynx cancer; TGCT cis rs3820068 0.626 rs61103742 chr1:15909153 A/C cg05660106 chr1:15850417 CASP9 1.05 12.15 0.74 7.58e-23 Systolic blood pressure; TGCT cis rs12908161 1.000 rs60957376 chr15:85280792 T/G cg11189052 chr15:85197271 WDR73 0.7 5.76 0.46 6.18e-8 Schizophrenia; TGCT cis rs3824867 0.920 rs7107853 chr11:47453518 T/C cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs9951602 0.920 rs3859334 chr18:76684193 G/A cg00806245 chr18:76673096 NA -0.31 -4.43 -0.37 2.01e-5 Obesity-related traits; TGCT cis rs9611519 0.929 rs926914 chr22:41418154 C/T cg13695892 chr22:41940480 POLR3H -0.53 -4.66 -0.39 7.97e-6 Neuroticism; TGCT cis rs644799 0.710 rs522536 chr11:95528714 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.65 0.61 2.18e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9611565 0.506 rs1883825 chr22:41703408 A/G cg13695892 chr22:41940480 POLR3H -0.64 -6.03 -0.48 1.78e-8 Vitiligo; TGCT cis rs7044106 0.762 rs966396 chr9:123453281 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.7 0.39 6.66e-6 Hip circumference adjusted for BMI; TGCT cis rs7923609 0.934 rs2893919 chr10:65134778 G/A cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.15e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs763014 0.966 rs4247097 chr16:654224 G/A cg09263875 chr16:632152 PIGQ 0.31 6.88 0.53 2.65e-10 Height; TGCT cis rs7786808 0.505 rs67537656 chr7:158192646 C/T cg01191920 chr7:158217561 PTPRN2 0.35 5.13 0.42 1.1e-6 Obesity-related traits; TGCT cis rs514406 0.861 rs12038438 chr1:53230581 A/T cg25767906 chr1:53392781 SCP2 0.48 5.57 0.45 1.49e-7 Monocyte count; TGCT trans rs4332037 0.707 rs62435132 chr7:1891315 C/T cg10840412 chr1:235813424 GNG4 0.86 6.67 0.51 7.59e-10 Bipolar disorder; TGCT cis rs9372253 0.934 rs9320327 chr6:110715194 T/A cg01119278 chr6:110721349 DDO -0.35 -5.68 -0.45 9.11e-8 Platelet distribution width; TGCT cis rs9473924 0.580 rs58105163 chr6:50832730 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs11098499 0.954 rs34858317 chr4:120387110 A/C cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs16866061 1.000 rs72974219 chr2:225423784 G/C cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs1552244 1.000 rs7626117 chr3:10140671 G/A cg00149659 chr3:10157352 C3orf10 0.76 5.73 0.46 7.13e-8 Alzheimer's disease; TGCT cis rs896854 0.654 rs896847 chr8:95972551 G/A cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.07e-9 Type 2 diabetes; TGCT cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs7769051 0.522 rs60133731 chr6:133095818 T/C cg07930552 chr6:133119739 C6orf192 1.21 4.81 0.4 4.24e-6 Type 2 diabetes nephropathy; TGCT cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs394563 0.622 rs237024 chr6:149721965 T/C cg16235748 chr6:149772707 ZC3H12D -0.44 -5.06 -0.41 1.46e-6 Dupuytren's disease; TGCT cis rs739496 0.947 rs7134740 chr12:111927739 G/A cg10833066 chr12:111807467 FAM109A 0.37 5.16 0.42 9.31e-7 Platelet count; TGCT cis rs889312 0.500 rs33323 chr5:56175566 C/G cg24531977 chr5:56204891 C5orf35 -0.5 -5.24 -0.43 6.6e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs10206020 0.879 rs72778007 chr2:1573178 C/T cg12573674 chr2:1569213 NA -0.49 -5.3 -0.43 5.1e-7 IgG glycosylation; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg01802117 chr1:53393560 SCP2 -0.39 -4.81 -0.4 4.37e-6 Monocyte count; TGCT cis rs346785 0.518 rs11077811 chr17:74285242 G/A cg09812376 chr17:74270190 QRICH2 -0.42 -6.4 -0.5 2.83e-9 White matter hyperintensities in ischemic stroke; TGCT cis rs6952808 0.609 rs10230383 chr7:1950113 T/C cg04267008 chr7:1944627 MAD1L1 -0.35 -4.44 -0.37 1.95e-5 Bipolar disorder and schizophrenia; TGCT cis rs9611565 0.592 rs9611612 chr22:41961189 T/C cg06634786 chr22:41940651 POLR3H -0.89 -8.45 -0.6 6.75e-14 Vitiligo; TGCT cis rs78545713 1.000 rs77281308 chr6:26250029 C/T cg12260798 chr6:26240519 HIST1H4F -0.54 -4.57 -0.38 1.16e-5 Iron status biomarkers (total iron binding capacity); TGCT cis rs763121 0.853 rs3761454 chr22:39066820 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs1568889 0.838 rs6484347 chr11:28040969 G/T cg06544937 chr11:28130018 METT5D1;KIF18A -0.89 -11.05 -0.7 3.48e-20 Bipolar disorder; TGCT cis rs9303401 0.659 rs12948133 chr17:56673602 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs9549260 0.564 rs9315785 chr13:41322732 T/C cg21288729 chr13:41239152 FOXO1 0.88 8.53 0.61 4.38e-14 Red blood cell count; TGCT cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.2 0.49 7.71e-9 Bipolar disorder; TGCT cis rs2836974 0.545 rs2776311 chr21:40716885 A/G cg11644478 chr21:40555479 PSMG1 0.64 6.06 0.48 1.52e-8 Cognitive function; TGCT cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg11301795 chr4:187892539 NA -0.34 -5.2 -0.42 7.94e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2120019 1.000 rs7175720 chr15:75348962 C/G cg09165964 chr15:75287851 SCAMP5 1.17 10.07 0.67 8.48e-18 Blood trace element (Zn levels); TGCT cis rs7666738 0.830 rs6830124 chr4:99054872 C/T cg18180107 chr4:99064573 C4orf37 -0.57 -5.06 -0.41 1.44e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.55 -5.42 -0.44 2.98e-7 Electroencephalogram traits; TGCT cis rs7772486 0.790 rs9485024 chr6:146142487 A/G cg23711669 chr6:146136114 FBXO30 -0.85 -9.89 -0.66 2.39e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6674176 0.561 rs4660263 chr1:44421433 A/C cg12908607 chr1:44402522 ARTN -0.68 -8.19 -0.59 2.7e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs56104184 0.830 rs17272645 chr19:49342366 C/G cg17863274 chr19:49399704 TULP2 0.41 5.26 0.43 6.03e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4975709 0.589 rs1466606 chr5:1865055 C/T cg14773178 chr5:1868261 NA 0.35 6.05 0.48 1.58e-8 Cardiovascular disease risk factors; TGCT cis rs10744422 0.528 rs6489245 chr12:123360151 G/A cg25930673 chr12:123319894 HIP1R -0.86 -5.13 -0.42 1.11e-6 Schizophrenia; TGCT cis rs12477438 0.798 rs972768 chr2:99682397 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs6952808 0.898 rs7799807 chr7:1868092 A/G cg22963979 chr7:1858916 MAD1L1 0.31 4.91 0.4 2.78e-6 Bipolar disorder and schizophrenia; TGCT cis rs10871290 0.801 rs3851726 chr16:74471644 G/C cg01733217 chr16:74700730 RFWD3 -0.59 -5.7 -0.46 8.27e-8 Breast cancer; TGCT cis rs4957048 0.577 rs56294732 chr5:568144 T/C cg09021430 chr5:549028 NA -0.42 -5.68 -0.45 9.25e-8 Ulcerative colitis; TGCT cis rs1153858 1.000 rs4774578 chr15:45646051 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs854765 0.724 rs2955371 chr17:17967397 G/A cg04398451 chr17:18023971 MYO15A 0.31 4.82 0.4 4.06e-6 Total body bone mineral density; TGCT cis rs9914544 0.583 rs11078422 chr17:18804413 C/T cg26378065 chr17:18585709 ZNF286B 0.54 4.71 0.39 6.58e-6 Educational attainment (years of education); TGCT cis rs13631 0.928 rs9411308 chr9:140000115 C/T cg14289826 chr9:140003911 NA 0.27 6.31 0.49 4.53e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs3806843 0.676 rs2563304 chr5:140072057 C/T cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs1453308 0.938 rs6431445 chr2:237181343 G/C cg19324714 chr2:237145437 ASB18 0.59 5.22 0.42 7.18e-7 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs35306767 0.761 rs12771539 chr10:1050653 A/G cg18964960 chr10:1102726 WDR37 0.78 5.46 0.44 2.45e-7 Eosinophil percentage of granulocytes; TGCT cis rs7681440 0.647 rs6814221 chr4:90805501 C/T cg20003494 chr4:90757398 SNCA -0.53 -4.71 -0.39 6.56e-6 Dementia with Lewy bodies; TGCT cis rs524281 0.861 rs7929909 chr11:65951698 C/T cg00563793 chr11:65837595 PACS1 0.57 4.91 0.4 2.8e-6 Electroencephalogram traits; TGCT cis rs62380364 0.542 rs601499 chr5:88052687 A/C cg24804195 chr5:87968844 LOC645323 -0.57 -5.58 -0.45 1.47e-7 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.705 rs72643683 chr1:15824905 C/A cg05660106 chr1:15850417 CASP9 1.18 13.63 0.77 2.04e-26 Systolic blood pressure; TGCT cis rs10883723 0.810 rs11191304 chr10:104255284 C/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7666738 0.830 rs13137808 chr4:99047095 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT trans rs1814175 0.817 rs10839397 chr11:49857074 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs41271473 0.500 rs4440831 chr1:228887522 C/T cg16512390 chr1:228756714 NA -0.52 -4.45 -0.37 1.91e-5 Chronic lymphocytic leukemia; TGCT cis rs4824093 0.544 rs73443951 chr22:50301251 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.99 -5.49 -0.44 2.19e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg05896524 chr21:47604654 C21orf56 -0.42 -4.45 -0.37 1.91e-5 Testicular germ cell tumor; TGCT cis rs7937682 0.562 rs519850 chr11:111376888 A/T cg09085632 chr11:111637200 PPP2R1B -0.68 -6.36 -0.5 3.55e-9 Primary sclerosing cholangitis; TGCT cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.38 0.5 3.25e-9 Cognitive function; TGCT cis rs16866061 1.000 rs11686590 chr2:225334070 A/G cg12698349 chr2:225449008 CUL3 0.96 9.57 0.65 1.4e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs7635838 0.859 rs9826803 chr3:11461863 G/A cg00170343 chr3:11313890 ATG7 0.64 6.11 0.48 1.2e-8 HDL cholesterol; TGCT cis rs9837602 0.507 rs1059905 chr3:99516879 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.44 4.98 0.41 2.08e-6 Breast cancer; TGCT cis rs459571 0.839 rs2519831 chr9:136886257 T/A cg13789015 chr9:136890014 NCRNA00094 0.39 6.95 0.53 1.84e-10 Platelet distribution width; TGCT cis rs916888 0.647 rs199524 chr17:44848438 G/T cg15921436 chr17:44337874 NA -0.43 -6.49 -0.5 1.89e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2242116 0.932 rs7646906 chr3:46949379 G/A cg23352942 chr3:46931381 PTH1R -0.35 -5.29 -0.43 5.44e-7 Birth weight; TGCT cis rs6860806 0.631 rs7736284 chr5:131588151 T/C cg24060327 chr5:131705240 SLC22A5 -0.58 -5.89 -0.47 3.46e-8 Breast cancer; TGCT cis rs6598955 0.671 rs6681452 chr1:26621101 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs765787 0.505 rs1648302 chr15:45494238 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.37 -0.43 3.77e-7 Uric acid levels; TGCT cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs875971 1.000 rs778694 chr7:65871558 A/G cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs1891275 0.515 rs1592051 chr10:93542186 A/G cg07889827 chr10:93443413 NA 0.31 6.51 0.5 1.65e-9 Intelligence (multi-trait analysis); TGCT cis rs79976124 0.879 rs10944856 chr6:66636960 G/C cg07460842 chr6:66804631 NA 0.56 5.03 0.41 1.71e-6 Type 2 diabetes; TGCT cis rs250677 0.687 rs41181 chr5:148444257 C/G cg18129178 chr5:148520854 ABLIM3 0.45 6.65 0.51 8.56e-10 Breast cancer; TGCT cis rs9611565 0.559 rs132761 chr22:42004371 C/T cg13695892 chr22:41940480 POLR3H 0.88 8.46 0.6 6.38e-14 Vitiligo; TGCT cis rs9733 0.566 rs112967224 chr1:150677263 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.81 0.4 4.38e-6 Tonsillectomy; TGCT cis rs986417 0.551 rs4901991 chr14:61065025 T/C cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs9611565 0.559 rs7290990 chr22:41964357 C/A cg06634786 chr22:41940651 POLR3H -0.88 -8.25 -0.6 1.98e-13 Vitiligo; TGCT cis rs7647973 0.626 rs62260723 chr3:49872124 T/C cg03060546 chr3:49711283 APEH -0.66 -5.91 -0.47 3.08e-8 Menarche (age at onset); TGCT cis rs73001065 0.551 rs79954596 chr19:19548643 T/G cg03709012 chr19:19516395 GATAD2A 0.9 4.9 0.4 2.99e-6 LDL cholesterol; TGCT cis rs72615157 0.716 rs75779608 chr7:99768957 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.63 -5.03 -0.41 1.7e-6 Lung function (FEV1/FVC); TGCT cis rs11024102 1.000 rs10766368 chr11:17014882 G/C cg15378786 chr11:17036137 PLEKHA7 0.49 4.57 0.38 1.18e-5 Glaucoma (primary angle closure); TGCT cis rs2070488 0.931 rs6599212 chr3:38558906 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT trans rs2688608 0.623 rs2633317 chr10:75690268 A/G cg13918328 chr10:52500089 ASAH2B 0.7 7.0 0.53 1.4e-10 Inflammatory bowel disease; TGCT cis rs6879260 1.000 rs1035411 chr5:179729519 A/G cg02891314 chr5:179741120 GFPT2 -0.42 -7.36 -0.55 2.24e-11 Height; TGCT cis rs2180341 0.521 rs12189967 chr6:127718058 G/A cg27446573 chr6:127587934 RNF146 0.64 5.83 0.46 4.45e-8 Breast cancer; TGCT cis rs12653946 0.846 rs4975758 chr5:1891174 C/G cg22472608 chr5:1891194 NA -0.67 -8.64 -0.61 2.34e-14 Prostate cancer; TGCT cis rs939658 1.000 rs4778935 chr15:79453282 T/C cg17916960 chr15:79447300 NA 0.52 8.17 0.59 2.94e-13 Refractive error; TGCT cis rs736408 0.521 rs13074853 chr3:52779801 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs2836950 0.501 rs2056844 chr21:40670460 G/C cg11890956 chr21:40555474 PSMG1 -0.67 -6.43 -0.5 2.49e-9 Menarche (age at onset); TGCT cis rs6918586 0.658 rs198828 chr6:26119459 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.68 -6.46 -0.5 2.15e-9 Schizophrenia; TGCT cis rs4595586 0.525 rs7977228 chr12:39395060 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7647973 1.000 rs11130190 chr3:49402137 T/C cg06212747 chr3:49208901 KLHDC8B 0.59 4.7 0.39 6.94e-6 Menarche (age at onset); TGCT cis rs7267979 1.000 rs4815409 chr20:25346697 C/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28785552 0.931 rs8112235 chr19:53239010 C/G cg04754360 chr19:53238445 ZNF611 -0.63 -4.93 -0.41 2.54e-6 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs6964587 1.000 rs6979085 chr7:91673623 C/T cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs8179 0.645 rs17766836 chr7:92258961 C/T cg15732164 chr7:92237376 CDK6 -0.29 -5.06 -0.41 1.46e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs7394190 0.748 rs4746139 chr10:75407649 A/C cg07699608 chr10:75541558 CHCHD1 0.63 4.7 0.39 6.67e-6 Incident atrial fibrillation; TGCT cis rs17376456 0.877 rs10063045 chr5:93457584 A/T cg21475434 chr5:93447410 FAM172A 0.61 4.49 0.37 1.6e-5 Diabetic retinopathy; TGCT cis rs9473924 0.542 rs9473952 chr6:50921779 T/C cg14470998 chr6:50812995 TFAP2B 1.26 7.3 0.55 3.1e-11 Body mass index; TGCT cis rs240764 0.853 rs4461738 chr6:100977940 T/C cg21058520 chr6:100914733 NA 0.35 4.63 0.38 9.07e-6 Neuroticism; TGCT cis rs11098499 0.697 rs6832410 chr4:120296800 A/G cg09307838 chr4:120376055 NA 0.66 6.48 0.5 1.98e-9 Corneal astigmatism; TGCT cis rs3733631 1.000 rs10007754 chr4:104627442 T/G cg24090629 chr4:104641072 TACR3 -0.73 -5.81 -0.46 4.96e-8 Menarche (age at onset); TGCT cis rs9611519 0.964 rs2179744 chr22:41621714 G/A cg13695892 chr22:41940480 POLR3H -0.51 -4.68 -0.39 7.46e-6 Neuroticism; TGCT cis rs17376456 1.000 rs66978370 chr5:93553633 G/A cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 7.92e-6 Diabetic retinopathy; TGCT cis rs9527 0.615 rs7089065 chr10:104723022 C/T cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs3099143 1.000 rs3106380 chr15:77104377 G/A cg21673338 chr15:77095150 SCAPER -0.52 -4.97 -0.41 2.15e-6 Recalcitrant atopic dermatitis; TGCT cis rs5167 0.781 rs909134 chr19:45493061 T/C cg13119609 chr19:45449297 APOC2 0.23 4.81 0.4 4.29e-6 Blood protein levels; TGCT cis rs7949030 0.626 rs11231141 chr11:62326265 T/C cg11742103 chr11:62369870 EML3;MTA2 0.61 8.72 0.62 1.56e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8032315 0.965 rs7497304 chr15:91429176 G/T cg05211768 chr15:91427848 FES 0.48 4.86 0.4 3.52e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4975616 0.804 rs31489 chr5:1342714 C/A cg07493874 chr5:1342172 CLPTM1L -0.26 -6.3 -0.49 4.77e-9 Lung cancer; TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg04321618 chr7:27170880 HOXA4 -0.52 -5.33 -0.43 4.47e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2075371 0.863 rs1646635 chr7:134006728 T/C cg11752832 chr7:134001865 SLC35B4 0.78 7.42 0.55 1.59e-11 Mean platelet volume; TGCT trans rs17685 0.753 rs11764129 chr7:75761890 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs12497850 0.931 rs28642807 chr3:48926816 A/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3015497 0.789 rs3015498 chr14:51112824 T/C cg04730355 chr14:51134070 SAV1 -0.68 -6.57 -0.51 1.26e-9 Mean platelet volume; TGCT cis rs4919694 1.000 rs12246689 chr10:104817031 C/T cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT cis rs7267979 1.000 rs4815418 chr20:25382211 T/G cg16686733 chr20:25566563 NINL -0.59 -6.05 -0.48 1.57e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs734999 1.000 rs734999 chr1:2513216 C/T cg18854424 chr1:2615690 NA 0.44 5.33 0.43 4.46e-7 Ulcerative colitis; TGCT cis rs7954584 0.567 rs7132055 chr12:122346034 A/G cg13699009 chr12:122356056 WDR66 -0.28 -5.48 -0.44 2.27e-7 Mean corpuscular volume; TGCT cis rs7666738 0.830 rs11727235 chr4:98946331 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6545883 0.965 rs7421663 chr2:61753786 C/T cg15711740 chr2:61764176 XPO1 -0.57 -5.25 -0.43 6.39e-7 Tuberculosis; TGCT cis rs9296092 0.538 rs62405943 chr6:33517359 A/G cg13560919 chr6:33536144 NA -0.21 -4.74 -0.39 5.87e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2235642 0.928 rs9932984 chr16:1605051 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.75 -0.46 6.52e-8 Coronary artery disease; TGCT cis rs6840360 0.642 rs2709838 chr4:152371364 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs302668 0.609 rs12270038 chr11:87870354 A/G cg01568784 chr11:87908783 RAB38 0.34 4.52 0.38 1.4e-5 Frontotemporal dementia; TGCT cis rs7681440 0.904 rs6816736 chr4:90765746 G/A cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs3820928 0.605 rs10186145 chr2:227781150 A/G cg11843606 chr2:227700838 RHBDD1 -0.51 -4.84 -0.4 3.86e-6 Pulmonary function; TGCT cis rs11209002 0.567 rs2755268 chr1:67539881 T/C cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs6845621 0.901 rs9991568 chr4:18922645 A/G cg12196642 chr4:18937545 NA 0.26 4.56 0.38 1.2e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs6880778 0.505 rs6891041 chr5:40406238 G/A cg01087697 chr5:40835557 RPL37 0.55 4.96 0.41 2.22e-6 Inflammatory bowel disease; TGCT cis rs9913156 0.793 rs72835644 chr17:4573667 G/A cg19197139 chr17:4613644 ARRB2 0.88 8.13 0.59 3.75e-13 Lymphocyte counts; TGCT cis rs7954584 0.567 rs11043246 chr12:122368944 G/A cg13699009 chr12:122356056 WDR66 0.29 5.69 0.46 8.63e-8 Mean corpuscular volume; TGCT cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg07092213 chr7:1199455 ZFAND2A -0.42 -4.46 -0.37 1.84e-5 Longevity;Endometriosis; TGCT cis rs1375194 0.582 rs13388224 chr2:33802902 T/C cg04131969 chr2:33951647 MYADML -0.57 -5.03 -0.41 1.66e-6 Response to antidepressants in depression; TGCT cis rs6088580 0.609 rs6058029 chr20:32969643 T/C cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs910316 0.763 rs175016 chr14:75459633 C/T cg08847533 chr14:75593920 NEK9 -0.84 -9.15 -0.64 1.4e-15 Height; TGCT cis rs74233809 1.000 rs2297787 chr10:104680137 T/A cg19559179 chr10:103815996 C10orf76 0.82 4.5 0.37 1.52e-5 Birth weight; TGCT cis rs751728 1.000 rs9394166 chr6:33751122 G/C cg13859433 chr6:33739653 LEMD2 -0.4 -7.27 -0.55 3.51e-11 Crohn's disease; TGCT cis rs950169 1.000 rs35658069 chr15:84780146 C/T cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.07e-8 Schizophrenia; TGCT cis rs1218582 0.772 rs2102423 chr1:154916068 A/G cg24250549 chr1:154909240 PMVK 0.62 6.21 0.49 7.36e-9 Prostate cancer; TGCT cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg06481639 chr22:41940642 POLR3H 0.62 5.59 0.45 1.4e-7 Vitiligo; TGCT cis rs9362426 0.608 rs56329400 chr6:88158712 A/G cg10919329 chr6:88182879 SLC35A1 -0.58 -4.48 -0.37 1.7e-5 Depressive episodes in bipolar disorder; TGCT cis rs2288884 1.000 rs78543982 chr19:52550867 T/C cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs4803468 1.000 rs10417997 chr19:41902361 G/A cg09537434 chr19:41945824 ATP5SL -0.9 -10.43 -0.68 1.11e-18 Height; TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg17178900 chr1:205818956 PM20D1 0.66 9.32 0.64 5.66e-16 Menarche (age at onset); TGCT cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs12579753 1.000 rs2401004 chr12:82214822 T/C cg07988820 chr12:82153109 PPFIA2 -0.64 -6.68 -0.51 7.15e-10 Resting heart rate; TGCT cis rs7666738 0.830 rs6830124 chr4:99054872 C/T cg05340658 chr4:99064831 C4orf37 -0.53 -5.87 -0.47 3.75e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6121246 0.567 rs6060399 chr20:30220823 C/T cg18721089 chr20:30220636 NA -0.65 -6.84 -0.52 3.17e-10 Mean corpuscular hemoglobin; TGCT trans rs1005277 0.579 rs1780115 chr10:38524773 C/T cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT trans rs7618501 0.933 rs1128535 chr3:49866392 C/T cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs138880 0.580 rs28562884 chr22:50312869 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.22 -7.53 -0.56 9.3e-12 Schizophrenia; TGCT cis rs9916302 0.904 rs7210488 chr17:37539819 T/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs739496 0.579 rs3177647 chr12:112277576 C/T cg10833066 chr12:111807467 FAM109A 0.39 5.36 0.43 3.91e-7 Platelet count; TGCT cis rs7267979 1.000 rs6050559 chr20:25329915 A/G cg14121845 chr20:25566513 NINL 0.51 5.5 0.44 2.05e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9389248 0.737 rs56358308 chr6:135306980 A/T cg24558204 chr6:135376177 HBS1L 0.46 4.65 0.39 8.46e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs1784581 0.588 rs9295180 chr6:162420579 T/C cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs6589563 0.737 rs73588403 chr11:116628271 C/T cg20660624 chr11:117307972 DSCAML1 -0.37 -4.92 -0.4 2.71e-6 Eosinophil counts; TGCT cis rs4372836 0.729 rs6547882 chr2:29037001 T/C cg09522027 chr2:28974177 PPP1CB -0.7 -7.26 -0.55 3.68e-11 Body mass index; TGCT cis rs4654899 0.758 rs6697284 chr1:21295599 G/A cg01072550 chr1:21505969 NA -0.55 -8.89 -0.62 6.13e-15 Superior frontal gyrus grey matter volume; TGCT cis rs9972944 0.756 rs6504350 chr17:63764336 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs6598541 0.505 rs12904731 chr15:99310956 A/G cg18742785 chr15:100270048 LYSMD4 -0.26 -4.51 -0.38 1.49e-5 Urate levels; TGCT cis rs2296887 0.673 rs3802680 chr10:104114886 A/G cg26089160 chr10:104170217 PSD 0.55 5.54 0.45 1.75e-7 Parkinson's disease; TGCT cis rs1018836 0.923 rs4735268 chr8:91629715 C/T cg16814680 chr8:91681699 NA -0.85 -8.83 -0.62 8.15e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs858239 0.509 rs57611130 chr7:23184552 C/A cg05602783 chr7:23145260 KLHL7 -0.62 -4.99 -0.41 1.97e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs28595532 0.764 rs55704595 chr4:119780607 G/A cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs9611565 0.605 rs202638 chr22:41855458 A/G cg06481639 chr22:41940642 POLR3H 0.68 5.99 0.47 2.14e-8 Vitiligo; TGCT cis rs6912958 0.525 rs586771 chr6:88064971 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.71 0.46 7.78e-8 Monocyte percentage of white cells; TGCT cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg02187348 chr16:89574699 SPG7 0.49 4.67 0.39 7.77e-6 Multiple myeloma (IgH translocation); TGCT cis rs4819052 1.000 rs9306123 chr21:46709922 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.99 8.17 0.59 3.09e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg08355456 chr11:67383691 NA 0.32 5.09 0.42 1.31e-6 Mean corpuscular volume; TGCT cis rs6089829 0.962 rs6122347 chr20:61661866 C/T cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs13326165 0.760 rs11707931 chr3:52358417 C/G cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1670533 1.000 rs6836350 chr4:1069973 C/T cg20887711 chr4:1340912 KIAA1530 0.63 4.95 0.41 2.32e-6 Recombination rate (females); TGCT cis rs524281 0.861 rs10791855 chr11:65963737 A/G cg00563793 chr11:65837595 PACS1 0.52 4.63 0.38 9.13e-6 Electroencephalogram traits; TGCT trans rs9329221 0.741 rs55975067 chr8:9806824 C/G cg06636001 chr8:8085503 FLJ10661 -0.77 -6.81 -0.52 3.74e-10 Neuroticism; TGCT cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg09359103 chr1:154839909 KCNN3 -0.62 -11.25 -0.71 1.15e-20 Prostate cancer; TGCT cis rs910316 1.000 rs10136948 chr14:75511075 C/T cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.99e-11 Height; TGCT cis rs7617773 0.817 rs11928691 chr3:48286765 C/T cg11946769 chr3:48343235 NME6 0.76 6.66 0.51 7.89e-10 Coronary artery disease; TGCT cis rs9811920 0.569 rs793445 chr3:99576644 T/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 6.82 0.52 3.63e-10 Axial length; TGCT cis rs4629710 0.592 rs66533103 chr6:131531016 C/T cg12606694 chr6:131520996 AKAP7 0.39 4.58 0.38 1.11e-5 Multiple myeloma (IgH translocation); TGCT cis rs7824557 0.767 rs1897950 chr8:11169551 C/A cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs7027203 0.595 rs7846827 chr9:96546525 C/T cg13679303 chr9:96623674 NA 0.53 7.59 0.56 6.5e-12 DNA methylation (variation); TGCT cis rs1218582 0.710 rs4845687 chr1:154878911 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.97 -0.53 1.64e-10 Prostate cancer; TGCT cis rs10197940 0.662 rs6735771 chr2:152273503 G/A cg19508488 chr2:152266495 RIF1 -0.74 -6.66 -0.51 7.77e-10 Lung cancer; TGCT cis rs1018836 0.545 rs7840203 chr8:91701223 A/G cg16814680 chr8:91681699 NA -1.05 -14.7 -0.8 6.21e-29 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1008375 1.000 rs12648232 chr4:17612537 C/T cg10189774 chr4:17578691 LAP3 -0.57 -5.07 -0.41 1.42e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28785552 0.769 rs11669363 chr19:53232321 C/A cg22067481 chr19:53234126 ZNF611 -0.46 -6.67 -0.51 7.47e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs17270561 0.514 rs10946805 chr6:26077891 C/T cg17691542 chr6:26056736 HIST1H1C 1.03 7.31 0.55 2.9e-11 Iron status biomarkers; TGCT cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs7172809 0.573 rs74025074 chr15:77439363 T/C cg22256960 chr15:77711686 NA -0.48 -4.52 -0.38 1.41e-5 Glucose homeostasis traits; TGCT cis rs3125734 0.660 rs4979780 chr10:63992740 A/C cg19640130 chr10:64028056 RTKN2 -0.39 -5.04 -0.41 1.64e-6 Rheumatoid arthritis; TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs2204008 0.837 rs1589395 chr12:38420405 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.7 0.57 3.77e-12 Bladder cancer; TGCT cis rs7267979 1.000 rs6050626 chr20:25428261 T/C cg14121845 chr20:25566513 NINL 0.51 5.46 0.44 2.44e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs597539 0.690 rs578791 chr11:68625809 C/T cg21963583 chr11:68658836 MRPL21 0.39 6.32 0.49 4.21e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9611565 0.525 rs9611548 chr22:41704143 G/T cg06634786 chr22:41940651 POLR3H -0.59 -5.54 -0.45 1.74e-7 Vitiligo; TGCT cis rs2153535 0.580 rs1414340 chr6:8491139 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs10927875 0.541 rs1739840 chr1:16342237 A/G cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs2797160 1.000 rs2797158 chr6:126009398 G/A cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs901683 0.702 rs73292848 chr10:46169752 T/C cg18240400 chr10:46168597 ANUBL1 0.56 4.63 0.38 8.93e-6 Red blood cell traits;Mean corpuscular volume; TGCT cis rs7666738 0.753 rs7657644 chr4:99057734 T/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17122693 0.748 rs72681630 chr14:51141250 A/G cg04730355 chr14:51134070 SAV1 1.33 11.77 0.73 6.15e-22 Cognitive performance; TGCT cis rs7607369 0.714 rs4674338 chr2:219647487 A/G cg02176678 chr2:219576539 TTLL4 0.38 4.87 0.4 3.36e-6 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs10875746 0.855 rs2269936 chr12:48425235 G/A cg20731937 chr12:48336164 NA 0.68 5.29 0.43 5.3e-7 Longevity (90 years and older); TGCT cis rs2075371 0.966 rs1646646 chr7:133996905 G/T cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs1205863 0.915 rs1205857 chr6:11942760 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs9915657 0.743 rs7502198 chr17:70110507 C/T cg06234051 chr17:70120541 SOX9 -0.24 -4.91 -0.4 2.76e-6 Thyroid hormone levels; TGCT cis rs3862030 0.503 rs6584505 chr10:104254412 C/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs4663969 0.545 rs4663334 chr2:234674924 C/T cg25479499 chr2:234183424 ATG16L1;SCARNA5 0.32 4.56 0.38 1.19e-5 Total bilirubin levels in HIV-1 infection; TGCT cis rs7614311 0.731 rs3774719 chr3:63950338 C/A cg22134162 chr3:63841271 THOC7 -0.45 -5.86 -0.47 4e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs7267979 1.000 rs2184000 chr20:25395878 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.9 7.25 0.55 3.93e-11 Platelet count; TGCT cis rs17331151 0.505 rs13066389 chr3:52565317 C/T cg15956490 chr3:53032818 SFMBT1 0.7 5.14 0.42 1.02e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8083786 1 rs8083786 chr18:12881361 A/G cg23544223 chr18:12777786 NA -0.54 -4.81 -0.4 4.31e-6 Rheumatoid arthritis; TGCT cis rs9913156 0.793 rs11655166 chr17:4559302 T/A cg19197139 chr17:4613644 ARRB2 -0.86 -7.97 -0.58 8.75e-13 Lymphocyte counts; TGCT cis rs7246967 0.673 rs34126042 chr19:22909218 G/A cg05241461 chr19:22816980 ZNF492 0.66 4.5 0.37 1.57e-5 Bronchopulmonary dysplasia; TGCT cis rs9457247 1.000 rs364451 chr6:167384756 G/A cg23791538 chr6:167370224 RNASET2 -0.53 -5.18 -0.42 8.72e-7 Crohn's disease; TGCT cis rs42648 0.566 rs13247629 chr7:89889585 A/G cg25739043 chr7:89950458 NA -0.48 -4.75 -0.39 5.64e-6 Homocysteine levels; TGCT trans rs1908814 0.516 rs35391955 chr8:11796728 A/C cg15556689 chr8:8085844 FLJ10661 0.75 7.07 0.54 9.74e-11 Neuroticism; TGCT trans rs1814175 0.791 rs10839468 chr11:49986288 A/G cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs78487399 0.908 rs76450091 chr2:43767189 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.64 4.51 0.38 1.49e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2239547 0.522 rs6768844 chr3:53004620 A/G cg11645453 chr3:52864694 ITIH4 -0.34 -5.45 -0.44 2.6e-7 Schizophrenia; TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs10992471 0.598 rs230222 chr9:95265558 C/G cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.93 -0.4 2.59e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7666738 0.791 rs4440223 chr4:99044796 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs28818218 chr4:98880575 A/C cg17366294 chr4:99064904 C4orf37 0.74 7.62 0.56 5.55e-12 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.645 rs7119101 chr11:49955665 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs8013055 0.796 rs8021330 chr14:106002352 C/A cg19700328 chr14:106028568 NA -0.49 -5.75 -0.46 6.66e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT trans rs1814175 0.817 rs1390676 chr11:50056778 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs172166 0.694 rs536704 chr6:28092603 T/G cg10876282 chr6:28092338 ZSCAN16 0.51 4.69 0.39 6.99e-6 Cardiac Troponin-T levels; TGCT cis rs1949733 0.701 rs2631735 chr4:8476118 A/G cg11789530 chr4:8429930 ACOX3 0.57 4.97 0.41 2.15e-6 Response to antineoplastic agents; TGCT cis rs9467773 1.000 rs6940188 chr6:26562029 G/C cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT trans rs10506458 0.915 rs2013042 chr12:63394211 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.46 -7.33 -0.55 2.6e-11 Hemostatic factors and hematological phenotypes; TGCT cis rs62380364 0.602 rs448809 chr5:88005828 G/T cg24804195 chr5:87968844 LOC645323 -0.61 -6.15 -0.48 9.97e-9 Intelligence (multi-trait analysis); TGCT cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg06035815 chr6:26189597 HIST1H4D 0.44 4.53 0.38 1.39e-5 Schizophrenia; TGCT cis rs62064224 0.720 rs8078837 chr17:30763537 A/G cg18200150 chr17:30822561 MYO1D 0.56 7.72 0.57 3.4e-12 Schizophrenia; TGCT cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg09323728 chr8:95962352 TP53INP1 -0.48 -6.22 -0.49 7.08e-9 Type 2 diabetes; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg16722931 chr17:75312494 SEPT9 1.09 6.82 0.52 3.52e-10 Gambling; TGCT cis rs2455799 0.613 rs12485852 chr3:15914511 G/C cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.68e-6 Mean platelet volume; TGCT cis rs2576037 0.583 rs680018 chr18:44409167 T/A cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.61 -0.38 9.88e-6 Personality dimensions; TGCT cis rs9640161 0.783 rs1132261 chr7:150059987 G/A cg10018233 chr7:150070692 REPIN1 0.33 4.86 0.4 3.41e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs9467711 0.520 rs13211947 chr6:25864818 C/T cg16898833 chr6:26189333 HIST1H4D 1.36 6.0 0.47 2.05e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg00786635 chr1:25594202 NA 0.54 5.69 0.45 8.79e-8 Erythrocyte sedimentation rate; TGCT cis rs7945705 0.869 rs7925728 chr11:9013002 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -5.87 -0.47 3.68e-8 Hemoglobin concentration; TGCT cis rs72945132 0.882 rs4567496 chr11:70193208 A/T cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs7586879 0.593 rs10198275 chr2:25130542 A/C cg15423357 chr2:25149977 NA 0.52 5.11 0.42 1.17e-6 Body mass index; TGCT cis rs3848445 1.000 rs3912263 chr17:14292908 A/C cg01636575 chr17:13447853 HS3ST3A1 0.74 4.56 0.38 1.22e-5 Protein quantitative trait loci; TGCT cis rs6570726 0.935 rs401888 chr6:145831535 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.962 rs4809455 chr20:61660781 G/C cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs4780355 0.843 rs243325 chr16:11354497 A/G cg00044050 chr16:11439710 C16orf75 0.6 5.35 0.43 4.05e-7 Crohn's disease and psoriasis; TGCT cis rs11969893 0.649 rs9390699 chr6:101306502 C/G cg12253828 chr6:101329408 ASCC3 1.22 5.92 0.47 3e-8 Economic and political preferences (immigration/crime); TGCT cis rs986417 1.000 rs1024223 chr14:60926119 C/T cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs2153535 0.580 rs4639392 chr6:8446547 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs4972806 0.814 rs6710370 chr2:177045969 T/C cg14324370 chr2:177042789 NA 0.71 6.81 0.52 3.67e-10 IgG glycosylation; TGCT cis rs10782582 0.609 rs5745545 chr1:76377356 A/G cg03433033 chr1:76189801 ACADM -0.5 -4.82 -0.4 4.13e-6 Daytime sleep phenotypes; TGCT cis rs7666738 0.830 rs969048 chr4:98988921 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs798554 0.655 rs798492 chr7:2799184 C/T cg25467336 chr7:2757616 NA 0.24 4.72 0.39 6.33e-6 Height; TGCT cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.36 -4.58 -0.38 1.11e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9814567 1.000 rs9883753 chr3:134247231 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -9.2 -0.64 1.11e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7017914 0.967 rs1477944 chr8:71615600 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT trans rs3780486 0.757 rs10758189 chr9:33125804 A/G cg04842962 chr6:43655489 MRPS18A 1.21 15.78 0.82 1.96e-31 IgG glycosylation; TGCT cis rs858239 0.704 rs199656 chr7:23337615 G/T cg05602783 chr7:23145260 KLHL7 0.72 5.72 0.46 7.3900000000000007e-08 Cerebrospinal fluid biomarker levels; TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.49 5.29 0.43 5.37e-7 Lymphocyte counts; TGCT cis rs727563 0.638 rs4820443 chr22:42193913 A/G cg06634786 chr22:41940651 POLR3H -0.82 -7.77 -0.57 2.62e-12 Crohn's disease;Inflammatory bowel disease; TGCT trans rs7726839 0.561 rs6555357 chr5:560923 A/G cg25482853 chr8:67687455 SGK3 1.09 9.17 0.64 1.25e-15 Obesity-related traits; TGCT cis rs7208859 0.573 rs216443 chr17:28931871 A/G cg13385521 chr17:29058706 SUZ12P 0.79 4.75 0.39 5.45e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7267979 0.873 rs6083853 chr20:25404541 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7552404 0.727 rs6683437 chr1:76316619 G/A cg22875332 chr1:76189707 ACADM 0.59 6.19 0.49 8.22e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1153858 1.000 rs10519021 chr15:45631795 G/A cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs13064411 0.696 rs6438161 chr3:113227637 G/A cg10517650 chr3:113235015 CCDC52 -0.32 -4.45 -0.37 1.85e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7824557 0.628 rs11991153 chr8:11203107 A/T cg21775007 chr8:11205619 TDH 0.67 6.53 0.51 1.49e-9 Retinal vascular caliber; TGCT trans rs3780486 0.846 rs12554995 chr9:33132044 A/G cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs2996428 0.667 rs61768932 chr1:3765671 G/C cg13057898 chr1:3703894 LRRC47 0.22 4.68 0.39 7.24e-6 Red cell distribution width; TGCT cis rs10510102 0.872 rs79865971 chr10:123700723 C/A cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs9858542 0.953 rs9811982 chr3:49624377 A/C cg03060546 chr3:49711283 APEH -0.63 -5.48 -0.44 2.28e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs9814567 0.806 rs11927539 chr3:134319448 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs877282 0.898 rs12357995 chr10:765739 T/C cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs9787249 0.957 rs1046988 chr1:40219065 A/G cg19912559 chr1:40204330 PPIE -0.46 -5.54 -0.45 1.73e-7 Blood protein levels; TGCT cis rs12477438 0.520 rs2516835 chr2:99779131 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs4700695 0.614 rs37232 chr5:65219869 A/C cg21114390 chr5:65439923 SFRS12 0.65 4.54 0.38 1.3e-5 Facial morphology (factor 19); TGCT cis rs7698623 0.850 rs1982623 chr4:88790777 C/G cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs7246657 0.653 rs10425441 chr19:37670648 T/C cg24025825 chr19:37761650 NA -0.32 -5.02 -0.41 1.79e-6 Coronary artery calcification; TGCT cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg16145915 chr7:1198662 ZFAND2A -0.56 -7.42 -0.55 1.65e-11 Longevity;Endometriosis; TGCT cis rs7180079 0.620 rs477966 chr15:64783725 A/G cg03791955 chr15:65024147 NA 0.28 4.49 0.37 1.59e-5 Monocyte count; TGCT cis rs9611565 0.512 rs2899349 chr22:42164660 T/C cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs1799949 0.965 rs9646413 chr17:41426157 A/G cg05368731 chr17:41323189 NBR1 1.04 12.44 0.75 1.48e-23 Menopause (age at onset); TGCT cis rs6933660 0.800 rs9383900 chr6:151782816 A/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.52 -4.65 -0.39 8.27e-6 Menarche (age at onset); TGCT cis rs4975616 0.836 rs13178866 chr5:1323212 C/T cg07493874 chr5:1342172 CLPTM1L -0.29 -7.01 -0.53 1.34e-10 Lung cancer; TGCT cis rs2361718 0.500 rs4889970 chr17:78096086 C/T cg17882374 chr17:78041429 CCDC40 -0.29 -4.46 -0.37 1.83e-5 Yeast infection; TGCT cis rs13256369 0.951 rs13270852 chr8:8566853 A/G cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs3947 0.950 rs2740592 chr8:11701253 A/G cg02840367 chr8:11660030 FDFT1 0.91 6.7 0.52 6.58e-10 Blood protein levels; TGCT cis rs617219 0.737 rs2166343 chr5:78484060 A/G cg23987322 chr5:78407566 BHMT 0.37 4.97 0.41 2.19e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10197940 0.662 rs1047957 chr2:152333773 C/T cg06191203 chr2:152266755 RIF1 -0.71 -6.28 -0.49 5.14e-9 Lung cancer; TGCT cis rs1163251 0.837 rs595283 chr1:120247887 C/G cg19096424 chr1:120255104 PHGDH -0.61 -5.93 -0.47 2.8e-8 Blood metabolite levels; TGCT cis rs9468199 0.505 rs72848793 chr6:27999578 A/G cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg23708337 chr7:1209742 NA 0.61 5.68 0.45 9.08e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17376456 0.542 rs10070350 chr5:93103753 C/G cg25358565 chr5:93447407 FAM172A 0.76 6.68 0.51 7.23e-10 Diabetic retinopathy; TGCT cis rs12048904 0.541 rs1571046 chr1:101299216 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.71 5.7 0.46 8.15e-8 Multiple sclerosis; TGCT cis rs514406 0.505 rs416968 chr1:53183513 A/G cg16325326 chr1:53192061 ZYG11B 0.85 12.44 0.75 1.44e-23 Monocyte count; TGCT cis rs4664308 1.000 rs17831251 chr2:160914156 C/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs7547997 0.615 rs35752748 chr1:158321565 A/C cg03528325 chr1:158223921 CD1A 0.33 4.55 0.38 1.25e-5 QRS duration; TGCT cis rs10489202 0.632 rs275143 chr1:168056724 A/G cg24449463 chr1:168025552 DCAF6 -0.58 -6.45 -0.5 2.26e-9 Schizophrenia; TGCT cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs694739 0.964 rs2510066 chr11:64052447 C/T cg23796481 chr11:64053134 BAD;GPR137 0.66 6.88 0.53 2.67e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT trans rs1005277 0.579 rs2472176 chr10:38382921 T/C cg17830980 chr10:43048298 ZNF37B -0.85 -10.98 -0.7 5.08e-20 Extrinsic epigenetic age acceleration; TGCT cis rs9814567 0.752 rs1534029 chr3:134330213 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7666738 0.570 rs11097612 chr4:99079772 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9790314 0.812 rs2004862 chr3:161135638 C/T cg03342759 chr3:160939853 NMD3 -0.46 -4.51 -0.38 1.48e-5 Morning vs. evening chronotype; TGCT cis rs301043 0.667 rs301004 chr12:95915680 T/C cg07805603 chr12:95869602 METAP2 0.34 4.58 0.38 1.13e-5 Immature fraction of reticulocytes; TGCT cis rs7674212 0.772 rs13113099 chr4:103974122 A/G cg16532752 chr4:104119610 CENPE -0.52 -4.8 -0.4 4.48e-6 Type 2 diabetes; TGCT cis rs4689388 0.890 rs4688989 chr4:6290594 T/C cg25554036 chr4:6271136 WFS1 0.54 7.61 0.56 5.93e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs4650994 0.544 rs2761469 chr1:178590638 A/C cg05059571 chr16:84539110 KIAA1609 0.52 10.37 0.68 1.56e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs1865760 0.566 rs9366634 chr6:26072396 C/G cg16482183 chr6:26056742 HIST1H1C 0.57 4.89 0.4 3.05e-6 Height; TGCT cis rs6089829 0.925 rs4809270 chr20:61676709 C/A cg02380750 chr20:61661411 NA 0.35 5.76 0.46 6.25e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs9926296 0.682 rs258328 chr16:89730314 C/T cg04287289 chr16:89883240 FANCA -0.54 -5.01 -0.41 1.86e-6 Vitiligo; TGCT cis rs7829975 0.606 rs7833171 chr8:8699761 C/T cg15556689 chr8:8085844 FLJ10661 0.66 5.8 0.46 5.2e-8 Mood instability; TGCT cis rs789852 0.764 rs1705999 chr3:194316333 C/T cg18000598 chr3:194342907 TMEM44 -0.76 -5.09 -0.42 1.31e-6 QT interval; TGCT cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs9467773 1.000 rs9461271 chr6:26554968 G/A cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.501 rs1133977 chr2:99741984 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.05 -14.93 -0.8 1.8e-29 Chronic sinus infection; TGCT cis rs4862750 0.832 rs4862744 chr4:187877074 T/A cg03452623 chr4:187889614 NA -0.34 -4.88 -0.4 3.21e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10540 0.915 rs12419209 chr11:494510 T/C cg03934478 chr11:495069 RNH1 0.36 5.84 0.46 4.26e-8 Body mass index; TGCT trans rs1814175 0.740 rs10839439 chr11:49918240 C/T cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs12765878 0.967 rs10883948 chr10:105667552 G/T cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs7621025 0.630 rs1681816 chr3:136474762 C/G cg15507776 chr3:136538369 TMEM22 -0.5 -4.56 -0.38 1.22e-5 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs250677 0.522 rs62378210 chr5:148384885 G/A cg18129178 chr5:148520854 ABLIM3 -0.36 -4.69 -0.39 7.23e-6 Breast cancer; TGCT cis rs5769765 0.955 rs61136468 chr22:50312679 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.13 -11.29 -0.71 9.05e-21 Schizophrenia; TGCT cis rs7213347 0.707 rs216215 chr17:2140668 C/T cg13315690 chr17:1944831 OVCA2;DPH1 -0.37 -4.7 -0.39 6.77e-6 Total body bone mineral density; TGCT cis rs875971 1.000 rs6970030 chr7:65968679 T/C cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs478304 0.637 rs11227255 chr11:65454044 C/T cg27068330 chr11:65405492 SIPA1 -1.0 -11.14 -0.71 2.07e-20 Acne (severe); TGCT cis rs9972944 0.756 rs8077164 chr17:63764645 C/T cg07283582 chr17:63770753 CCDC46 -0.25 -5.11 -0.42 1.2e-6 Total body bone mineral density; TGCT cis rs734999 0.505 rs4073286 chr1:2539901 A/C cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs904251 0.828 rs1757178 chr6:37486310 C/T cg08126542 chr6:37504118 NA 0.42 5.55 0.45 1.66e-7 Cognitive performance; TGCT trans rs3780486 0.881 rs10738906 chr9:33135634 T/C cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT cis rs7681440 0.904 rs6532192 chr4:90764131 G/A cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.82e-8 Dementia with Lewy bodies; TGCT cis rs6430585 0.583 rs3087343 chr2:136622543 T/G cg07169764 chr2:136633963 MCM6 1.22 12.03 0.73 1.46e-22 Corneal structure; TGCT cis rs4689388 0.926 rs4308429 chr4:6294001 A/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg21280719 chr6:42927975 GNMT -0.37 -4.54 -0.38 1.32e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7772486 0.840 rs2814867 chr6:146334030 C/A cg05347473 chr6:146136440 FBXO30 0.55 5.12 0.42 1.15e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 0.673 rs17015224 chr1:209968918 G/A cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs7666738 0.830 rs3846444 chr4:99032888 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2663905 0.611 rs1509558 chr15:81391244 C/T cg27045999 chr15:81426544 C15orf26 -0.52 -5.09 -0.42 1.32e-6 QT interval (drug interaction); TGCT cis rs2688608 0.592 rs13013 chr10:75562161 C/A cg23231163 chr10:75533350 FUT11 -0.28 -4.69 -0.39 7.19e-6 Inflammatory bowel disease; TGCT cis rs9818758 0.607 rs9880088 chr3:49178990 G/A cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7246657 0.943 rs7258692 chr19:37818829 C/A cg18154014 chr19:37997991 ZNF793 0.91 6.09 0.48 1.29e-8 Coronary artery calcification; TGCT cis rs7267979 1.000 rs8125868 chr20:25324410 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7819412 0.594 rs60921132 chr8:10964969 T/A cg15556689 chr8:8085844 FLJ10661 -0.73 -7.13 -0.54 7.33e-11 Triglycerides; TGCT cis rs910316 1.000 rs175443 chr14:75601963 C/T cg11812906 chr14:75593930 NEK9 -0.73 -7.13 -0.54 7.35e-11 Height; TGCT cis rs7674212 0.541 rs2720448 chr4:104030589 C/T cg16532752 chr4:104119610 CENPE -0.62 -5.36 -0.43 3.83e-7 Type 2 diabetes; TGCT cis rs4927850 0.666 rs4927853 chr3:195752053 G/C cg22891161 chr3:195456627 MUC20 -0.23 -4.55 -0.38 1.24e-5 Pancreatic cancer; TGCT cis rs11971779 0.941 rs6954453 chr7:139031794 C/T cg07862535 chr7:139043722 LUC7L2 0.79 5.97 0.47 2.38e-8 Diisocyanate-induced asthma; TGCT cis rs6570726 0.599 rs9376951 chr6:145898911 C/T cg13319975 chr6:146136371 FBXO30 -0.68 -6.23 -0.49 6.81e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.966 rs2257705 chr20:25264664 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10751667 0.666 rs7394958 chr11:965944 C/G cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.66e-13 Alzheimer's disease (late onset); TGCT cis rs1801251 1.000 rs35212961 chr2:233582762 C/T cg25237894 chr2:233734115 C2orf82 0.32 5.81 0.46 5.01e-8 Coronary artery disease; TGCT cis rs950169 0.922 rs4842940 chr15:84831225 C/T cg17173187 chr15:85201210 NMB -0.52 -5.23 -0.42 7.11e-7 Schizophrenia; TGCT cis rs981844 0.712 rs1037650 chr4:154737657 G/A cg14289246 chr4:154710475 SFRP2 -1.0 -9.32 -0.64 5.46e-16 Response to statins (LDL cholesterol change); TGCT cis rs10779751 1.000 rs10779751 chr1:11284336 A/G cg08854313 chr1:11322531 MTOR 0.96 8.74 0.62 1.37e-14 Body mass index; TGCT trans rs2727020 0.702 rs609054 chr11:49219725 C/G cg03929089 chr4:120376271 NA 0.71 7.91 0.58 1.2e-12 Coronary artery disease; TGCT cis rs2251381 0.750 rs2776250 chr21:30528094 T/G cg08807101 chr21:30365312 RNF160 0.53 4.65 0.39 8.51e-6 Selective IgA deficiency; TGCT cis rs6951245 0.744 rs10265758 chr7:1172518 C/T cg23708337 chr7:1209742 NA 0.53 5.6 0.45 1.29e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7192750 0.586 rs2335712 chr16:71906597 A/G cg06353428 chr16:71660113 MARVELD3 -0.8 -6.09 -0.48 1.34e-8 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs80282103 0.717 rs41299206 chr10:1120236 T/C cg08668510 chr10:1095578 IDI1 1.06 5.26 0.43 6.17e-7 Glomerular filtration rate (creatinine); TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg02953382 chr22:24373134 LOC391322 -0.83 -9.46 -0.65 2.54e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7100689 0.524 rs7902460 chr10:82199263 T/A cg01528321 chr10:82214614 TSPAN14 0.71 6.15 0.48 9.9e-9 Post bronchodilator FEV1; TGCT cis rs6964587 1.000 rs13239875 chr7:91716104 G/A cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs2180341 0.960 rs7756884 chr6:127684018 A/G cg27446573 chr6:127587934 RNF146 1.21 10.87 0.7 9.57e-20 Breast cancer; TGCT cis rs709400 0.663 rs1803283 chr14:103986255 C/T cg12935359 chr14:103987150 CKB 0.4 5.92 0.47 2.88e-8 Body mass index; TGCT cis rs6690583 0.623 rs893620 chr1:85425821 T/C cg20280350 chr1:85513789 MCOLN3 -0.68 -4.49 -0.37 1.6e-5 Serum sulfate level; TGCT cis rs1461503 0.868 rs7126785 chr11:122839564 C/A cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs3096299 0.754 rs2965942 chr16:89510327 G/A cg06640241 chr16:89574553 SPG7 0.74 7.97 0.58 8.88e-13 Multiple myeloma (IgH translocation); TGCT cis rs9372498 0.536 rs62422229 chr6:118959288 T/C cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT trans rs1814175 0.645 rs11040535 chr11:49808669 C/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs3096299 0.967 rs28575874 chr16:89469890 C/T cg06640241 chr16:89574553 SPG7 0.65 6.24 0.49 6.32e-9 Multiple myeloma (IgH translocation); TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg22166914 chr1:53195759 ZYG11B 0.38 6.19 0.49 8.03e-9 Monocyte count; TGCT cis rs1395 0.744 rs11126935 chr2:27476740 G/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs68170813 0.652 rs6947674 chr7:107193504 T/C cg02696742 chr7:106810147 HBP1 -0.62 -4.93 -0.4 2.59e-6 Coronary artery disease; TGCT cis rs9972944 0.729 rs6504351 chr17:63765275 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.31 -0.43 4.9e-7 Total body bone mineral density; TGCT cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.93e-10 Bipolar disorder; TGCT cis rs10992471 0.580 rs7030920 chr9:95122952 A/G cg14631576 chr9:95140430 CENPP -0.32 -4.84 -0.4 3.72e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6089829 0.816 rs6062397 chr20:61668268 A/G cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs78487399 0.808 rs10200815 chr2:43673273 C/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -5.31 -0.43 4.82e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2012796 1.000 rs7153469 chr14:81820979 T/G cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs910316 0.763 rs175490 chr14:75545685 A/G cg11812906 chr14:75593930 NEK9 0.62 5.62 0.45 1.17e-7 Height; TGCT cis rs35306767 0.714 rs28512382 chr10:1092195 G/C cg20503657 chr10:835505 NA 0.6 6.85 0.52 3.05e-10 Eosinophil percentage of granulocytes; TGCT cis rs7809950 0.817 rs10224503 chr7:107075569 A/C cg23024343 chr7:107201750 COG5 -0.5 -6.99 -0.53 1.48e-10 Coronary artery disease; TGCT cis rs6570726 0.791 rs447992 chr6:145817184 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6121246 0.529 rs6120862 chr20:30199459 T/C cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs8042680 0.554 rs8035844 chr15:91519642 C/T cg23684204 chr15:91497937 RCCD1 0.36 4.63 0.38 9e-6 Type 2 diabetes; TGCT cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Intelligence (multi-trait analysis); TGCT cis rs3771570 1.000 rs62193175 chr2:242284405 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg18402987 chr7:1209562 NA 0.75 6.35 0.5 3.67e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17221829 0.644 rs7943100 chr11:89382037 C/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 8.95e-6 Anxiety in major depressive disorder; TGCT cis rs2201841 0.960 rs10889677 chr1:67725120 C/A cg25131922 chr1:68698529 GPR177 0.44 4.66 0.39 8.11e-6 Ulcerative colitis;Psoriasis;Crohn's disease; TGCT cis rs1878931 0.501 rs17136359 chr16:3420814 C/T cg22508957 chr16:3507546 NAT15 0.38 4.8 0.4 4.54e-6 Body mass index (adult); TGCT cis rs3015497 0.789 rs2934688 chr14:51112360 G/A cg04730355 chr14:51134070 SAV1 -0.68 -6.57 -0.51 1.26e-9 Mean platelet volume; TGCT cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.95 -10.7 -0.69 2.52e-19 Age at first birth; TGCT cis rs78456975 0.689 rs10194040 chr2:1543293 T/G cg12573674 chr2:1569213 NA -0.49 -4.8 -0.4 4.43e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.83 -0.4 3.91e-6 Prudent dietary pattern; TGCT cis rs4654899 0.758 rs7530739 chr1:21447480 C/A cg01072550 chr1:21505969 NA -0.57 -9.35 -0.64 4.68e-16 Superior frontal gyrus grey matter volume; TGCT cis rs11098499 0.648 rs2002047 chr4:120257228 A/G cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Corneal astigmatism; TGCT cis rs10789285 0.650 rs4265389 chr1:69693244 G/A ch.1.69469992R chr1:69697404 NA 0.31 4.54 0.38 1.32e-5 Psoriasis; TGCT cis rs11105298 0.891 rs11105316 chr12:89925200 T/G cg00757033 chr12:89920650 WDR51B 0.3 4.78 0.39 4.9100000000000004e-06 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs950027 0.620 rs1617634 chr15:45615578 A/G cg26924012 chr15:45694286 SPATA5L1 0.82 9.1 0.63 1.85e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs10802346 0.636 rs12047380 chr1:246394817 C/T cg12448285 chr1:245534821 KIF26B -0.36 -4.89 -0.4 3.11e-6 Fractional exhaled nitric oxide (childhood); TGCT cis rs16957091 0.647 rs7166705 chr15:43265126 C/A cg17935677 chr15:44119062 WDR76 0.52 4.67 0.39 7.6e-6 MGMT methylation in smokers; TGCT cis rs4253772 0.591 rs6520010 chr22:46721223 G/A cg24881330 chr22:46731750 TRMU 0.94 6.36 0.5 3.54e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs1997103 1.000 rs10270618 chr7:55396712 T/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1372520 0.577 rs1811443 chr4:90747883 G/C cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs2224391 0.628 rs2753232 chr6:5250765 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs12477438 0.798 rs6716913 chr2:99580641 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs7246657 0.943 rs4803229 chr19:37864682 T/G cg18154014 chr19:37997991 ZNF793 0.74 5.33 0.43 4.48e-7 Coronary artery calcification; TGCT cis rs4919694 1.000 rs4917382 chr10:104838510 G/A cg04362960 chr10:104952993 NT5C2 1.07 7.2 0.54 5.11e-11 Arsenic metabolism; TGCT cis rs1797081 0.561 rs2603795 chr10:16860256 A/G cg23933602 chr10:16859644 RSU1 0.7 7.05 0.53 1.1e-10 Platelet distribution width; TGCT trans rs1814175 0.715 rs11040586 chr11:49858432 T/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs36051895 0.632 rs11791350 chr9:5172907 G/T cg02405213 chr9:5042618 JAK2 -0.7 -9.12 -0.63 1.65e-15 Pediatric autoimmune diseases; TGCT cis rs3784262 0.528 rs1994926 chr15:58334587 C/T cg12031962 chr15:58353849 ALDH1A2 -0.41 -6.22 -0.49 6.9e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9291683 0.609 rs12507050 chr4:10007305 G/T cg11266682 chr4:10021025 SLC2A9 0.68 9.86 0.66 2.76e-17 Bone mineral density; TGCT cis rs9650657 0.645 rs9969657 chr8:10515278 A/G cg27411982 chr8:10470053 RP1L1 0.22 4.92 0.4 2.73e-6 Neuroticism; TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg23131131 chr22:24373011 LOC391322 -0.81 -9.08 -0.63 2.09e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1372520 0.873 rs2737026 chr4:90779823 A/G cg20003494 chr4:90757398 SNCA -0.65 -5.22 -0.42 7.45e-7 Neuroticism; TGCT cis rs7100689 0.577 rs9420359 chr10:82054873 C/T cg01528321 chr10:82214614 TSPAN14 0.7 6.78 0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs7666738 0.861 rs28821920 chr4:98962743 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg19318889 chr4:1322082 MAEA 0.26 6.49 0.5 1.82e-9 Longevity; TGCT cis rs1757171 0.542 rs3818985 chr6:37484214 G/T cg25019722 chr6:37503610 NA -0.5 -7.68 -0.57 4.04e-12 Cognitive performance; TGCT cis rs1008375 1.000 rs1558378 chr4:17650351 T/C cg10189774 chr4:17578691 LAP3 0.6 5.29 0.43 5.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs700590 0.723 rs160042 chr5:88143526 C/T cg22951263 chr5:87985283 NA 0.54 5.06 0.41 1.48e-6 Educational attainment (years of education); TGCT cis rs17376456 0.877 rs66696214 chr5:93424533 G/A cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs3960554 0.709 rs56163935 chr7:75788744 T/C cg17325771 chr7:75508891 RHBDD2 -0.54 -4.51 -0.38 1.46e-5 Eotaxin levels; TGCT cis rs2439831 0.850 rs2228368 chr15:44102010 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.86 6.25 0.49 6.04e-9 Lung cancer in ever smokers; TGCT cis rs910316 0.839 rs35977276 chr14:75637359 A/C cg23033748 chr14:75592666 NEK9 -0.29 -4.88 -0.4 3.17e-6 Height; TGCT cis rs74233809 0.534 rs176185 chr10:104556054 G/C cg05855489 chr10:104503620 C10orf26 -0.75 -5.01 -0.41 1.8e-6 Birth weight; TGCT cis rs6940638 0.662 rs7759694 chr6:27240956 C/T cg05738196 chr6:26577821 NA -0.5 -4.5 -0.37 1.56e-5 Intelligence (multi-trait analysis); TGCT cis rs7822232 0.908 rs6558297 chr8:145143934 C/T cg26272248 chr8:145163034 KIAA1875 -0.49 -4.81 -0.4 4.24e-6 Blood metabolite levels; TGCT cis rs739496 0.579 rs7294623 chr12:112317096 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs5769765 0.908 rs9616370 chr22:50306316 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.48 -7.05 -0.53 1.11e-10 Schizophrenia; TGCT cis rs1552244 0.882 rs7636817 chr3:10014876 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.64 -0.51 8.67e-10 Alzheimer's disease; TGCT cis rs2797160 0.651 rs6569437 chr6:126034540 T/G cg05901451 chr6:126070800 HEY2 0.73 6.81 0.52 3.66e-10 Endometrial cancer; TGCT cis rs826838 0.900 rs9739128 chr12:38948960 A/T cg26384229 chr12:38710491 ALG10B 1.05 10.5 0.69 7.87e-19 Heart rate; TGCT cis rs4563143 0.514 rs112540771 chr19:29316100 C/T cg12756686 chr19:29218302 NA 0.62 4.67 0.39 7.69e-6 Methadone dose in opioid dependence; TGCT cis rs6089829 0.855 rs6062781 chr20:61667128 G/A cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs904251 1.000 rs12212090 chr6:37431808 A/G cg08126542 chr6:37504118 NA -0.4 -5.27 -0.43 5.92e-7 Cognitive performance; TGCT cis rs6555855 0.830 rs1592817 chr5:168744302 A/G cg26492514 chr5:168728236 SLIT3 0.28 4.45 0.37 1.91e-5 Menarche (age at onset); TGCT cis rs9911578 1.000 rs10401050 chr17:56953786 A/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs57994353 1.000 rs57994353 chr9:139356987 T/C cg13741927 chr9:139327495 INPP5E -0.25 -5.81 -0.46 4.88e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs7662987 0.517 rs1311618 chr4:100012612 A/G cg12011299 chr4:100065546 ADH4 0.4 4.76 0.39 5.33e-6 Smoking initiation; TGCT cis rs11578119 0.933 rs10919416 chr1:170441709 T/C cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs12701220 0.803 rs12701432 chr7:1052453 C/T cg07217954 chr7:1067459 C7orf50 -0.49 -4.9 -0.4 2.95e-6 Bronchopulmonary dysplasia; TGCT cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9467711 0.606 rs12176317 chr6:26372786 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs669446 0.558 rs6429631 chr1:44113441 T/C cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs12220898 0.749 rs4483512 chr10:50480390 G/A cg06072769 chr10:50146962 WDFY4 0.38 4.98 0.41 2.07e-6 Inflammatory biomarkers; TGCT cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2456568 0.803 rs10831140 chr11:93640689 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -6.24 -0.49 6.39e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs6964587 0.869 rs11769726 chr7:91485231 A/G cg17063962 chr7:91808500 NA -0.85 -8.94 -0.63 4.52e-15 Breast cancer; TGCT cis rs4253772 0.701 rs9627280 chr22:46643964 T/C cg09491104 chr22:46646882 C22orf40 -0.5 -5.35 -0.43 4.04e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs9435341 0.965 rs1730864 chr1:107607810 C/T cg09367891 chr1:107599246 PRMT6 -0.62 -5.17 -0.42 8.93e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs7923452 1.000 rs7923452 chr10:30751171 T/C cg18806716 chr10:30721971 MAP3K8 0.7 6.19 0.49 7.95e-9 Itch intensity from mosquito bite; TGCT cis rs807669 0.525 rs2282684 chr22:19184244 C/T cg02655711 chr22:19163373 SLC25A1 0.24 4.58 0.38 1.13e-5 Metabolite levels; TGCT cis rs259282 0.583 rs12981373 chr19:33108189 C/T cg26639809 chr19:33781782 NA 0.24 4.78 0.39 4.77e-6 Schizophrenia; TGCT cis rs644799 0.542 rs10831415 chr11:95466159 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.59 5.77 0.46 6.06e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7000551 0.715 rs7839577 chr8:22307325 T/A cg12081754 chr8:22256438 SLC39A14 0.33 5.47 0.44 2.43e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9902453 0.808 rs12452288 chr17:28235220 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.28 0.55 3.32e-11 Coffee consumption (cups per day); TGCT cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg22764044 chr5:178986830 RUFY1 -0.47 -5.27 -0.43 5.84e-7 Lung cancer; TGCT cis rs9467773 0.869 rs742090 chr6:26415637 A/C cg26531700 chr6:26746687 NA -0.51 -4.97 -0.41 2.2e-6 Intelligence (multi-trait analysis); TGCT cis rs5769765 0.825 rs9616780 chr22:50292763 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.91 0.47 3.12e-8 Schizophrenia; TGCT cis rs35160687 0.901 rs34048420 chr2:86529748 A/G cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.48e-7 Night sleep phenotypes; TGCT cis rs200810 0.694 rs112311189 chr6:98030472 T/C cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.65 -4.44 -0.37 1.94e-5 Body mass index; TGCT cis rs74181299 0.571 rs6728523 chr2:65282708 G/C cg05010058 chr2:65284262 CEP68 0.49 5.01 0.41 1.79e-6 Pulse pressure; TGCT cis rs9910055 0.529 rs850851 chr17:42177674 C/T cg13607699 chr17:42295918 UBTF -0.6 -4.93 -0.4 2.59e-6 Total body bone mineral density; TGCT cis rs1865760 0.516 rs9393683 chr6:26066198 A/G cg16482183 chr6:26056742 HIST1H1C 0.57 4.99 0.41 1.99e-6 Height; TGCT cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg08280861 chr8:58055591 NA 0.48 5.85 0.46 4.17e-8 Developmental language disorder (linguistic errors); TGCT cis rs6714788 0.546 rs12712062 chr2:100654307 A/T cg07810366 chr2:100720526 AFF3 -0.36 -5.07 -0.41 1.43e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg25767906 chr1:53392781 SCP2 0.49 5.52 0.44 1.87e-7 Monocyte count; TGCT cis rs1371867 0.764 rs1020171 chr8:101288610 T/C cg06002616 chr8:101225028 SPAG1 -0.57 -6.77 -0.52 4.48e-10 Atrioventricular conduction; TGCT cis rs4722585 0.605 rs10268883 chr7:26200417 C/T cg03781084 chr7:26191726 NFE2L3 -0.5 -5.04 -0.41 1.61e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs4072705 0.967 rs4838200 chr9:127451057 A/G cg13476313 chr9:127244764 NR5A1 -0.28 -4.45 -0.37 1.93e-5 Menarche (age at onset); TGCT cis rs7925523 0.838 rs60507107 chr11:61463769 C/T cg18476690 chr11:61125255 CYBASC3 0.27 4.53 0.38 1.36e-5 Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid); TGCT cis rs804280 0.662 rs11250164 chr8:11610686 C/T cg26752888 chr8:11627280 NEIL2 0.58 4.49 0.37 1.58e-5 Myopia (pathological); TGCT cis rs7772486 0.686 rs4896827 chr6:145953338 T/A cg05347473 chr6:146136440 FBXO30 0.48 4.56 0.38 1.19e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7412746 0.611 rs72704679 chr1:150897477 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg18402987 chr7:1209562 NA 0.75 6.29 0.49 4.9e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2243480 1.000 rs7456042 chr7:65299778 T/C cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs3806843 0.521 rs246061 chr5:140324656 C/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs57024841 0.517 rs28578007 chr9:139838690 T/C cg00693599 chr9:139836323 FBXW5 0.21 4.68 0.39 7.33e-6 Beta-trace protein levels; TGCT cis rs4851266 1.000 rs12990462 chr2:100827216 G/A cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs78545713 0.892 rs113432940 chr6:26256324 T/A cg12260798 chr6:26240519 HIST1H4F -0.49 -4.52 -0.38 1.4e-5 Iron status biomarkers (total iron binding capacity); TGCT cis rs2455799 0.517 rs1579901 chr3:15938463 C/G cg12172478 chr3:16357591 RFTN1 -0.33 -4.81 -0.4 4.31e-6 Mean platelet volume; TGCT cis rs909685 1.000 rs909685 chr22:39747671 T/A cg17798944 chr22:39715225 SNORD43;RPL3 0.66 6.42 0.5 2.65e-9 Rheumatoid arthritis; TGCT cis rs6121246 0.529 rs6060144 chr20:30178624 A/G cg21427119 chr20:30132790 HM13 -0.44 -6.39 -0.5 3.11e-9 Mean corpuscular hemoglobin; TGCT cis rs1670533 1.000 rs7669399 chr4:1058478 T/G cg20887711 chr4:1340912 KIAA1530 0.69 5.48 0.44 2.32e-7 Recombination rate (females); TGCT cis rs4665809 0.878 rs35709953 chr2:26334997 G/A cg22920501 chr2:26401640 FAM59B 0.72 5.73 0.46 7.24e-8 Gut microbiome composition (summer); TGCT cis rs2871473 1.000 rs1030024 chr2:103105769 A/T cg09003973 chr2:102972529 NA -0.64 -4.52 -0.38 1.4e-5 Blood protein levels; TGCT cis rs7678296 0.649 rs4585313 chr4:37240236 C/T cg06805348 chr4:37245195 KIAA1239 -0.58 -4.92 -0.4 2.68e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs4319547 0.956 rs10773302 chr12:123043145 G/T cg23029597 chr12:123009494 RSRC2 -0.3 -4.83 -0.4 3.98e-6 Body mass index; TGCT cis rs8070128 0.534 rs2955350 chr17:17953548 G/A cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs7659604 1.000 rs35224452 chr4:122664677 C/T cg19748678 chr4:122722346 EXOSC9 0.57 5.5 0.44 2.07e-7 Type 2 diabetes; TGCT cis rs9467773 1.000 rs6925703 chr6:26521589 G/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg07092213 chr7:1199455 ZFAND2A -0.46 -4.92 -0.4 2.73e-6 Longevity;Endometriosis; TGCT cis rs826838 0.967 rs1352122 chr12:39130885 G/A cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs9916302 0.851 rs6503502 chr17:37501855 A/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs10193935 0.901 rs13384323 chr2:42631346 C/T cg27598129 chr2:42591480 NA -0.36 -5.17 -0.42 9.2e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12493885 0.697 rs73153977 chr3:153659196 G/T cg17054900 chr3:154042577 DHX36 -0.52 -4.68 -0.39 7.33e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs910316 0.967 rs2010678 chr14:75567178 C/T cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs1568889 0.774 rs11030235 chr11:28212375 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 10.5 0.69 7.72e-19 Bipolar disorder; TGCT cis rs7647973 0.626 rs9870858 chr3:49769071 C/T cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs3749237 0.595 rs3870338 chr3:49557051 A/G cg02487422 chr3:49467188 NICN1 0.57 5.88 0.47 3.54e-8 Resting heart rate; TGCT cis rs6693567 0.565 rs834237 chr1:150363930 A/G cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs4851266 1.000 rs11686372 chr2:100827907 C/A cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs2050392 1.000 rs2050392 chr10:30691503 G/A cg18806716 chr10:30721971 MAP3K8 -0.44 -5.17 -0.42 9.28e-7 Inflammatory bowel disease; TGCT cis rs1475911 1.000 rs12482477 chr21:43517233 T/A cg08663969 chr21:43620345 ABCG1 0.19 4.48 0.37 1.7e-5 IgG glycosylation; TGCT cis rs11030122 0.702 rs7102215 chr11:3943970 C/T cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs3617 0.539 rs9985365 chr3:52953844 A/G cg10802521 chr3:52805072 NEK4 0.54 6.27 0.49 5.52e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3796352 0.527 rs11715498 chr3:52943551 G/C cg07884673 chr3:53033167 SFMBT1 0.46 4.7 0.39 6.89e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4077515 0.967 rs11145874 chr9:139290011 G/A cg13741927 chr9:139327495 INPP5E -0.2 -4.67 -0.39 7.55e-6 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs12142240 0.698 rs45449893 chr1:46859024 A/G cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg00024416 chr22:24240387 NA 0.35 5.93 0.47 2.79e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs936229 0.690 rs2445618 chr15:75035256 T/C cg10253484 chr15:75165896 SCAMP2 -0.59 -5.0 -0.41 1.89e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs2050392 0.517 rs160018 chr10:30772703 T/C cg18806716 chr10:30721971 MAP3K8 -0.5 -5.67 -0.45 9.52e-8 Inflammatory bowel disease; TGCT cis rs9948 0.655 rs62152771 chr2:97447121 C/G cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT trans rs10506458 1.000 rs10506458 chr12:63445092 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.62 -0.56 5.8e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs6912958 0.559 rs242270 chr6:88062190 C/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.25 -0.49 6.08e-9 Monocyte percentage of white cells; TGCT cis rs2970818 0.831 rs2970810 chr12:4608103 A/G cg09670175 chr12:4923468 KCNA6 0.2 4.45 0.37 1.91e-5 Phosphorus levels; TGCT cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg16423285 chr20:60520624 NA -0.69 -7.11 -0.54 8.23e-11 Body mass index; TGCT cis rs4951018 0.821 rs11240547 chr1:205632932 A/G cg14159672 chr1:205819179 PM20D1 0.4 4.53 0.38 1.36e-5 Prostate-specific antigen levels; TGCT cis rs360798 0.512 rs4461246 chr2:63027671 C/T cg17519650 chr2:63277830 OTX1 -0.57 -4.98 -0.41 2.1e-6 Coronary artery disease; TGCT cis rs9303401 0.527 rs12946522 chr17:56768103 A/C cg25039879 chr17:56429692 SUPT4H1 0.52 4.52 0.38 1.41e-5 Cognitive test performance; TGCT cis rs79349575 0.811 rs1057897 chr17:47005509 T/G cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs7666738 0.546 rs10440329 chr4:98903735 C/T cg05340658 chr4:99064831 C4orf37 0.56 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.729 rs137831 chr22:41903813 A/C cg17554472 chr22:41940697 POLR3H -0.47 -5.07 -0.41 1.43e-6 Vitiligo; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs9534288 0.619 rs6561292 chr13:46683560 G/T cg15192986 chr13:46630673 CPB2 0.51 6.19 0.49 7.96e-9 Blood protein levels; TGCT cis rs9916302 0.861 rs33933929 chr17:37426441 A/C cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs4517514 0.509 rs2156434 chr11:89896417 A/G cg05041596 chr11:89867385 NAALAD2 0.53 5.08 0.42 1.33e-6 Trans fatty acid levels; TGCT cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs7726839 0.540 rs4957080 chr5:644552 A/C cg20362242 chr5:692897 TPPP -0.5 -4.57 -0.38 1.17e-5 Obesity-related traits; TGCT cis rs2486012 1.000 rs61770287 chr1:44359205 C/T cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs60843830 1.000 rs62114505 chr2:242426 A/G cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.81 0.52 3.81e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs981844 1.000 rs2405431 chr4:154656396 A/G cg14289246 chr4:154710475 SFRP2 1.04 8.19 0.59 2.74e-13 Response to statins (LDL cholesterol change); TGCT cis rs10479542 0.702 rs13183521 chr5:178975606 A/G cg14820908 chr5:178986412 RUFY1 -0.44 -4.52 -0.38 1.44e-5 Lung cancer; TGCT cis rs1008375 0.966 rs6449330 chr4:17703949 C/T cg18681998 chr4:17616180 MED28 -0.77 -7.84 -0.58 1.77e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3772130 0.962 rs7629369 chr3:121566282 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs7666738 0.800 rs12163918 chr4:98835794 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.18 0.42 8.78e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs17221829 0.626 rs10830340 chr11:89413850 C/T cg02982614 chr11:89391479 FOLH1B -0.28 -4.66 -0.39 7.94e-6 Anxiety in major depressive disorder; TGCT cis rs4820539 0.966 rs5751587 chr22:23470090 G/A cg14186256 chr22:23484241 RTDR1 0.99 12.58 0.75 6.81e-24 Bone mineral density; TGCT cis rs7364180 0.515 rs6002503 chr22:42208672 A/G cg13695892 chr22:41940480 POLR3H -0.56 -5.54 -0.45 1.75e-7 Alzheimer's disease biomarkers; TGCT cis rs2361718 0.603 rs12951255 chr17:78085597 A/G cg08005872 chr17:78999347 NA 0.27 4.57 0.38 1.18e-5 Yeast infection; TGCT cis rs7219021 0.739 rs4793993 chr17:47008546 C/T cg26022315 chr17:47021804 SNF8 -0.54 -4.65 -0.39 8.2e-6 Schizophrenia or bipolar disorder; TGCT cis rs11718455 0.960 rs4682712 chr3:43997971 T/C cg08738300 chr3:44038990 NA 0.83 6.19 0.49 8.13e-9 Coronary artery disease; TGCT cis rs4400599 0.786 rs11265123 chr1:154087255 G/T cg08031413 chr1:154528842 UBE2Q1 0.27 4.62 0.38 9.41e-6 Platelet distribution width; TGCT cis rs2842992 1.000 rs2842992 chr6:160071159 G/A cg11366901 chr6:160182831 ACAT2 0.92 6.27 0.49 5.5e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs7607369 0.648 rs7559629 chr2:219657013 A/T cg02176678 chr2:219576539 TTLL4 -0.47 -6.0 -0.47 1.98e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg23205692 chr1:25664452 TMEM50A 0.49 5.16 0.42 9.32e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs4664308 0.905 rs62177860 chr2:160960571 C/T cg03641300 chr2:160917029 PLA2R1 -0.28 -6.89 -0.53 2.44e-10 Idiopathic membranous nephropathy; TGCT cis rs67460515 0.892 rs13073147 chr3:161045237 T/C cg03342759 chr3:160939853 NMD3 -0.49 -5.29 -0.43 5.28e-7 Parkinson's disease; TGCT cis rs16866061 0.515 rs13020268 chr2:225437923 C/T cg12698349 chr2:225449008 CUL3 1.12 15.51 0.81 8.08e-31 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs314253 1.000 rs314253 chr17:7091650 A/G cg17016524 chr17:7405958 POLR2A 0.18 5.08 0.42 1.35e-6 LDL cholesterol levels;Cholesterol, total;LDL cholesterol;Liver enzyme levels (alkaline phosphatase); TGCT cis rs35306767 0.715 rs12777801 chr10:1036285 T/A cg26597838 chr10:835615 NA 0.63 7.0 0.53 1.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs7772486 0.754 rs702323 chr6:146008274 A/G cg23711669 chr6:146136114 FBXO30 -0.85 -9.45 -0.65 2.66e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs72781680 0.898 rs56315094 chr2:23941952 T/C cg08917208 chr2:24149416 ATAD2B 0.77 4.71 0.39 6.52e-6 Lymphocyte counts; TGCT cis rs1997103 1.000 rs1997103 chr7:55395390 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7681440 0.874 rs10028246 chr4:90766704 G/A cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs9969804 0.818 rs6479429 chr9:95501785 A/T cg13940029 chr9:95239186 CENPP;ASPN -0.17 -4.51 -0.38 1.47e-5 Height; TGCT cis rs9660992 0.512 rs12123773 chr1:205122420 C/G cg00857998 chr1:205179979 DSTYK 0.48 4.48 0.37 1.68e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs7943203 0.568 rs597788 chr11:108256859 C/T cg04873221 chr11:107992290 ACAT1 -0.59 -5.0 -0.41 1.87e-6 Red blood cell count;Mean corpuscular volume; TGCT cis rs67478160 0.643 rs11847468 chr14:104220295 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs1887596 0.624 rs9319306 chr13:27151170 A/G cg01312412 chr13:27282625 NA 0.29 5.32 0.43 4.77e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs2549003 1.000 rs2548997 chr5:131835395 C/T cg21138405 chr5:131827807 IRF1 -0.19 -5.03 -0.41 1.65e-6 Asthma (sex interaction); TGCT cis rs12580194 1.000 rs58332180 chr12:55711353 C/A cg20672549 chr12:56432144 IKZF4 0.26 4.67 0.39 7.82e-6 Cancer; TGCT cis rs595982 0.702 rs638050 chr19:49375676 A/G cg21252483 chr19:49399788 TULP2 -0.27 -4.81 -0.4 4.37e-6 Red cell distribution width; TGCT cis rs2070433 1.000 rs2839306 chr21:47954219 G/T cg12379764 chr21:47803548 PCNT -0.54 -4.65 -0.39 8.47e-6 Lymphocyte counts; TGCT cis rs12893668 0.572 rs1606 chr14:104161281 G/A cg26031613 chr14:104095156 KLC1 -0.59 -5.05 -0.41 1.53e-6 Reticulocyte count; TGCT cis rs9911578 0.967 rs4076229 chr17:56937256 C/T cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs11601602 0.576 rs4075635 chr11:28511643 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.69 5.67 0.45 9.35e-8 Obesity-related traits; TGCT cis rs7666738 0.753 rs1527520 chr4:98929164 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3806843 0.576 rs246011 chr5:140336405 G/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10779751 0.770 rs11121691 chr1:11181327 C/T cg08854313 chr1:11322531 MTOR -0.82 -6.58 -0.51 1.17e-9 Body mass index; TGCT cis rs9512730 0.553 rs6491211 chr13:28049533 A/G cg04070771 chr13:27998621 GTF3A 0.51 4.58 0.38 1.13e-5 Schizophrenia; TGCT cis rs72781680 0.848 rs56218741 chr2:23977377 A/C cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs1552244 0.554 rs9878047 chr3:9985457 T/C cg00149659 chr3:10157352 C3orf10 0.61 4.44 0.37 1.97e-5 Alzheimer's disease; TGCT cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg06634786 chr22:41940651 POLR3H -0.72 -6.68 -0.51 7.15e-10 Vitiligo; TGCT cis rs11031096 0.782 rs4910888 chr11:4152915 G/A cg18678763 chr11:4115507 RRM1 -0.46 -5.87 -0.47 3.74e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9911578 1.000 rs302840 chr17:56673079 C/G cg12560992 chr17:57184187 TRIM37 0.78 9.62 0.65 1.03e-16 Intelligence (multi-trait analysis); TGCT cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg11211951 chr8:145729740 GPT -0.25 -5.8 -0.46 5.1e-8 Age at first birth; TGCT cis rs7584330 0.554 rs7582964 chr2:238385766 C/T cg14458575 chr2:238380390 NA -0.44 -4.44 -0.37 1.99e-5 Prostate cancer; TGCT cis rs453301 0.598 rs2921383 chr8:8892221 C/T cg06636001 chr8:8085503 FLJ10661 0.77 6.89 0.53 2.53e-10 Joint mobility (Beighton score); TGCT cis rs9660180 0.967 rs61422524 chr1:1767565 C/A cg13866156 chr1:1669148 SLC35E2 -0.23 -5.51 -0.44 1.97e-7 Body mass index; TGCT cis rs12615966 0.872 rs72830464 chr2:105395283 G/A cg16465502 chr2:105461796 NA 0.79 5.07 0.41 1.39e-6 Pancreatic cancer; TGCT cis rs11098499 0.754 rs11724409 chr4:120252361 A/G cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9325144 0.647 rs61930266 chr12:38922048 A/G cg26384229 chr12:38710491 ALG10B -0.56 -5.07 -0.41 1.4e-6 Morning vs. evening chronotype; TGCT cis rs2334880 0.638 rs17343777 chr16:71439172 T/A cg06353428 chr16:71660113 MARVELD3 -1.28 -7.41 -0.55 1.67e-11 Malaria; TGCT cis rs17376456 0.825 rs74825443 chr5:93254973 T/C cg25358565 chr5:93447407 FAM172A 0.98 7.85 0.58 1.68e-12 Diabetic retinopathy; TGCT cis rs7017914 0.905 rs3110253 chr8:71937553 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs910316 0.967 rs8007539 chr14:75664953 T/C cg08847533 chr14:75593920 NEK9 -0.93 -9.92 -0.67 1.93e-17 Height; TGCT cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg18654377 chr3:49208889 KLHDC8B 0.37 4.85 0.4 3.65e-6 Menarche (age at onset); TGCT cis rs8180040 0.620 rs7373821 chr3:47080127 A/C cg27129171 chr3:47204927 SETD2 0.71 8.51 0.61 4.8e-14 Colorectal cancer; TGCT cis rs10876993 0.928 rs1628552 chr12:58082142 C/T cg15848620 chr12:58087721 OS9 -0.73 -6.05 -0.48 1.6e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs116095464 0.558 rs62346508 chr5:203668 T/C cg22857025 chr5:266934 NA -0.35 -6.52 -0.51 1.63e-9 Breast cancer; TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg15687855 chr3:44754131 ZNF502 -0.45 -5.38 -0.43 3.62e-7 Depressive symptoms; TGCT cis rs6088590 0.965 rs6120730 chr20:33385102 G/C cg24642439 chr20:33292090 TP53INP2 0.68 6.06 0.48 1.48e-8 Coronary artery disease; TGCT trans rs4576506 1.000 rs10116483 chr9:31539221 G/A cg05645557 chr17:16290151 NA 1.19 6.62 0.51 9.86e-10 Psychosis and Alzheimer's disease; TGCT cis rs916888 0.610 rs199529 chr17:44837217 A/C cg15921436 chr17:44337874 NA 0.51 7.12 0.54 7.74e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2982552 0.873 rs977532 chr6:152068883 C/T cg22157087 chr6:152012887 ESR1 0.2 4.77 0.39 5e-6 Bone properties (heel); TGCT cis rs11864453 0.612 rs11862813 chr16:72132356 C/T cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs752590 0.832 rs6542124 chr2:113951924 C/A cg27425262 chr2:113953981 PSD4;LOC440839 0.43 4.83 0.4 3.93e-6 Mucinous ovarian carcinoma; TGCT cis rs6500602 0.702 rs11645519 chr16:4538989 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.57 0.45 1.51e-7 Schizophrenia; TGCT cis rs12220238 1.000 rs11000888 chr10:75901929 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4975616 0.869 rs465498 chr5:1325803 A/G cg07493874 chr5:1342172 CLPTM1L -0.29 -6.9 -0.53 2.32e-10 Lung cancer; TGCT cis rs4808199 0.948 rs12982276 chr19:19459800 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.71 5.73 0.46 7.17e-8 Nonalcoholic fatty liver disease; TGCT cis rs6785206 0.527 rs35970262 chr3:128642936 C/T cg25356066 chr3:128598488 ACAD9 -0.74 -4.65 -0.39 8.51e-6 Lymphocyte percentage of white cells; TGCT trans rs9929218 0.529 rs8060790 chr16:68729112 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.55 6.87 0.53 2.77e-10 Colorectal cancer; TGCT cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.71 7.58 0.56 6.92e-12 Blood metabolite levels; TGCT cis rs2948294 0.588 rs4840913 chr8:8116906 A/C cg15462221 chr8:8086144 FLJ10661 -0.54 -4.74 -0.39 5.73e-6 Red cell distribution width; TGCT cis rs9653442 0.712 rs6714788 chr2:100686173 A/G cg22139774 chr2:100720529 AFF3 0.43 7.8 0.57 2.15e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs208520 1.000 rs208535 chr6:66962286 G/A cg07460842 chr6:66804631 NA -0.83 -7.52 -0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs4713118 0.513 rs149962 chr6:28015918 G/A cg10876282 chr6:28092338 ZSCAN16 0.5 4.6 0.38 1.01e-5 Parkinson's disease; TGCT cis rs700651 0.821 rs700663 chr2:198670478 T/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial aneurysm; TGCT cis rs11651000 0.817 rs11657479 chr17:45822901 T/C cg06532163 chr17:45867833 NA 0.33 4.82 0.4 4.14e-6 IgG glycosylation; TGCT cis rs10876993 0.672 rs2640611 chr12:58037757 T/A cg15848620 chr12:58087721 OS9 -0.72 -5.78 -0.46 5.57e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs6500602 0.598 rs3859155 chr16:4593741 A/C cg08645402 chr16:4508243 NA -0.17 -4.76 -0.39 5.39e-6 Schizophrenia; TGCT cis rs6424115 1.000 rs2179395 chr1:24148365 T/C cg15997130 chr1:24165203 NA 0.9 10.23 0.68 3.51e-18 Immature fraction of reticulocytes; TGCT cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs877282 0.945 rs34367686 chr10:791868 G/C cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs8070740 1.000 rs8076900 chr17:5327927 C/G cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.55 0.38 1.27e-5 Menopause (age at onset); TGCT cis rs611744 0.967 rs702805 chr8:109235929 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs12908161 1.000 rs17601029 chr15:85347709 A/G cg11189052 chr15:85197271 WDR73 0.69 5.69 0.46 8.57e-8 Schizophrenia; TGCT cis rs8072100 0.967 rs4289035 chr17:45707211 C/T cg08085267 chr17:45401833 C17orf57 -0.43 -4.63 -0.38 9.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs936229 0.813 rs1378938 chr15:75096443 T/C cg10253484 chr15:75165896 SCAMP2 -0.65 -5.23 -0.42 7.07e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs11190604 1.000 rs6584383 chr10:102303065 C/G cg23241863 chr10:102295624 HIF1AN 0.73 5.23 0.43 6.9e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg17054783 chr10:134559939 INPP5A 0.25 4.79 0.4 4.66e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12477438 0.798 rs1349779 chr2:99645055 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -5.89 -0.47 3.39e-8 Chronic sinus infection; TGCT cis rs4727027 0.704 rs12537763 chr7:148903984 G/A cg23583168 chr7:148888333 NA -0.79 -10.49 -0.69 8.14e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs208520 0.770 rs2224422 chr6:66883993 G/A cg07460842 chr6:66804631 NA -0.9 -9.33 -0.64 5.29e-16 Exhaled nitric oxide output; TGCT cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4845570 1.000 rs4845570 chr1:151759104 C/T cg07092448 chr1:151763213 TDRKH 1.16 9.27 0.64 7.5e-16 Coronary artery disease; TGCT cis rs6752107 1.000 rs2241880 chr2:234183368 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.81 0.4 4.36e-6 Crohn's disease;Inflammatory bowel disease; TGCT trans rs2727020 0.595 rs10466496 chr11:49501514 C/T cg03929089 chr4:120376271 NA -0.76 -9.15 -0.63 1.43e-15 Coronary artery disease; TGCT cis rs1843834 0.539 rs6749402 chr2:225443901 T/G cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs17376456 1.000 rs34756085 chr5:93556294 A/G cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 7.92e-6 Diabetic retinopathy; TGCT cis rs76878669 0.561 rs10896111 chr11:66115690 T/C cg18002602 chr11:66138449 SLC29A2 -0.53 -6.58 -0.51 1.16e-9 Educational attainment (years of education); TGCT cis rs11190604 0.767 rs10736150 chr10:102195341 G/A cg23241863 chr10:102295624 HIF1AN -0.66 -4.9 -0.4 2.98e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg02073558 chr3:44770973 ZNF501 0.71 7.07 0.54 9.87e-11 Depressive symptoms; TGCT cis rs6684514 1.000 rs12038217 chr1:156248297 C/T cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1215050 0.818 rs6532703 chr4:98777486 A/T cg05340658 chr4:99064831 C4orf37 0.46 5.51 0.44 1.94e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2836950 0.545 rs1888489 chr21:40533164 T/C cg06238570 chr21:40685208 BRWD1 -0.61 -6.34 -0.49 3.83e-9 Menarche (age at onset); TGCT cis rs3771570 0.901 rs9052 chr2:242434809 G/T cg21155796 chr2:242212141 HDLBP 0.93 6.79 0.52 4.12e-10 Prostate cancer; TGCT cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg11644478 chr21:40555479 PSMG1 -0.63 -5.92 -0.47 2.93e-8 Cognitive function; TGCT cis rs75229567 0.618 rs11177819 chr12:70134836 T/G cg10114359 chr12:70132523 RAB3IP 1.36 6.73 0.52 5.51e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs13177918 0.559 rs10447225 chr5:149834454 C/T cg14059543 chr5:149831962 NA -0.62 -7.86 -0.58 1.63e-12 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs651907 0.588 rs1707608 chr3:101644769 C/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.55 5.45 0.44 2.66e-7 Colorectal cancer; TGCT cis rs9581857 0.547 rs76971629 chr13:28051031 C/T cg22138327 chr13:27999177 GTF3A 0.74 4.82 0.4 4.15e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs13256369 1.000 rs9329165 chr8:8576642 C/T cg18904891 chr8:8559673 CLDN23 -0.58 -5.34 -0.43 4.31e-7 Obesity-related traits; TGCT cis rs10875746 0.669 rs10875779 chr12:48629869 G/A cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs6810498 0.804 rs907495 chr4:26081011 T/C cg04611865 chr4:25162039 SEPSECS -0.5 -4.49 -0.37 1.63e-5 Alcohol dependence; TGCT cis rs7772486 0.846 rs2748496 chr6:146321829 T/A cg23711669 chr6:146136114 FBXO30 0.82 8.92 0.63 5.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs56176327 0.532 rs9849038 chr3:49771990 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Intelligence (multi-trait analysis); TGCT cis rs9486719 0.947 rs12194971 chr6:96911073 T/C cg18709589 chr6:96969512 KIAA0776 -0.72 -5.24 -0.43 6.58e-7 Migraine;Coronary artery disease; TGCT cis rs2204008 0.521 rs7311188 chr12:38542813 C/G cg26384229 chr12:38710491 ALG10B -0.53 -4.7 -0.39 6.9e-6 Bladder cancer; TGCT cis rs35306767 0.953 rs35693858 chr10:979813 C/T cg26597838 chr10:835615 NA 0.56 7.67 0.57 4.27e-12 Eosinophil percentage of granulocytes; TGCT cis rs250677 0.687 rs250678 chr5:148434830 C/T cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs3806843 0.735 rs2563306 chr5:140070017 C/T cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs986417 1.000 rs1951115 chr14:60922006 G/C cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs77633900 0.614 rs280013 chr15:76978139 C/T cg21673338 chr15:77095150 SCAPER 0.54 5.15 0.42 1.01e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs2242116 0.796 rs7623898 chr3:46974172 C/T cg02527881 chr3:46936655 PTH1R 0.32 6.0 0.47 1.99e-8 Birth weight; TGCT cis rs301043 0.500 rs188523 chr12:95916843 A/G cg07805603 chr12:95869602 METAP2 0.44 5.42 0.44 2.92e-7 Immature fraction of reticulocytes; TGCT cis rs11098499 0.863 rs10034450 chr4:120455649 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs7666738 0.830 rs6532720 chr4:99043781 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg26338869 chr17:61819248 STRADA -0.58 -5.23 -0.43 6.97e-7 Prudent dietary pattern; TGCT cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs1635 0.655 rs2159275 chr6:28308446 G/A cg15743358 chr6:28303923 ZNF323 -1.29 -6.5 -0.5 1.73e-9 Schizophrenia; TGCT cis rs2309757 1 rs2309757 chr2:100807725 T/C cg22139774 chr2:100720529 AFF3 -0.35 -5.29 -0.43 5.24e-7 Educational attainment (college completion); TGCT cis rs9916302 0.904 rs12452880 chr17:37591149 G/C cg15445000 chr17:37608096 MED1 0.32 4.68 0.39 7.47e-6 Glomerular filtration rate (creatinine); TGCT cis rs9926296 0.568 rs7203907 chr16:89833774 C/G cg04287289 chr16:89883240 FANCA 0.91 11.7 0.72 9.35e-22 Vitiligo; TGCT cis rs9457247 1.000 rs408080 chr6:167392522 T/C cg25258033 chr6:167368657 RNASET2 0.2 4.82 0.4 4.03e-6 Crohn's disease; TGCT cis rs2692947 0.644 rs2969491 chr2:96794982 C/T cg05933789 chr2:97190408 NA 0.16 4.64 0.38 8.81e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7666738 0.791 rs4699324 chr4:98967496 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1215050 0.791 rs1506438 chr4:98789542 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.47 0.44 2.37e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12497850 0.931 rs7430198 chr3:48988760 T/C cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.94e-6 Parkinson's disease; TGCT cis rs9807989 0.507 rs4851572 chr2:103019031 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg06035815 chr6:26189597 HIST1H4D -0.44 -4.58 -0.38 1.12e-5 Schizophrenia; TGCT cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg25703541 chr22:24373054 LOC391322 -0.91 -10.75 -0.69 1.94e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9303401 0.659 rs35082010 chr17:56936867 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs710216 0.843 rs3768043 chr1:43419354 C/A cg03128534 chr1:43423976 SLC2A1 -0.61 -5.02 -0.41 1.79e-6 Red cell distribution width; TGCT cis rs447921 1.000 rs372126 chr17:74413216 A/G cg09812376 chr17:74270190 QRICH2 0.44 4.5 0.37 1.57e-5 Mitochondrial DNA levels; TGCT cis rs9926296 0.562 rs4785725 chr16:89893243 A/G cg05177932 chr16:89631655 NA 0.29 4.93 0.41 2.53e-6 Vitiligo; TGCT cis rs2637266 0.875 rs12783253 chr10:78378108 A/G cg18941641 chr10:78392320 NA 0.4 4.75 0.39 5.48e-6 Pulmonary function; TGCT cis rs4319547 0.695 rs10846699 chr12:122853073 A/G cg08088222 chr12:122070432 ORAI1 -0.25 -4.56 -0.38 1.22e-5 Body mass index; TGCT cis rs9560113 0.580 rs9560116 chr13:112193731 G/A cg10483660 chr13:112241077 NA 0.32 4.64 0.38 8.8e-6 Menarche (age at onset); TGCT cis rs3020736 0.500 rs7292241 chr22:42492063 G/A cg15557168 chr22:42548783 NA 0.22 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg23221052 chr5:179740743 GFPT2 0.36 5.73 0.46 7.23e-8 Height; TGCT cis rs9926296 0.712 rs459920 chr16:89730827 T/C cg04287289 chr16:89883240 FANCA -0.54 -5.01 -0.41 1.86e-6 Vitiligo; TGCT cis rs7662987 0.517 rs2851268 chr4:100027878 A/G cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs2235642 0.821 rs8051895 chr16:1602811 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -5.06 -0.41 1.46e-6 Coronary artery disease; TGCT cis rs17122693 1.000 rs2934682 chr14:51061207 A/T cg04730355 chr14:51134070 SAV1 1.1 8.05 0.59 5.75e-13 Cognitive performance; TGCT cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs950776 0.518 rs62008174 chr15:78808947 C/T cg06917634 chr15:78832804 PSMA4 0.97 9.62 0.65 1.05e-16 Sudden cardiac arrest; TGCT cis rs7666738 0.830 rs36047842 chr4:99004902 C/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.07e-9 Type 2 diabetes; TGCT cis rs875971 0.965 rs7794930 chr7:65778546 A/C cg18876405 chr7:65276391 NA -0.31 -4.57 -0.38 1.16e-5 Aortic root size; TGCT cis rs72627509 0.857 rs55762216 chr4:57765731 G/C cg26694713 chr4:57773883 REST 0.73 6.57 0.51 1.27e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6088590 1.000 rs10048849 chr20:33419680 C/T cg06115741 chr20:33292138 TP53INP2 0.65 5.3 0.43 5.12e-7 Coronary artery disease; TGCT cis rs9733 0.650 rs2048558 chr1:150571730 A/G cg13175981 chr1:150552382 MCL1 0.54 6.21 0.49 7.46e-9 Tonsillectomy; TGCT cis rs4975709 0.544 rs4975748 chr5:1866025 G/A cg15595755 chr5:1867978 NA 0.47 5.56 0.45 1.57e-7 Cardiovascular disease risk factors; TGCT cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.86 0.4 3.44e-6 Schizophrenia; TGCT cis rs11874712 1.000 rs28757346 chr18:43696540 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.09 0.42 1.29e-6 Migraine - clinic-based; TGCT cis rs6714710 0.557 rs17490429 chr2:98449024 G/A cg26665480 chr2:98280029 ACTR1B 0.66 6.27 0.49 5.45e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs11792861 0.926 rs12686736 chr9:111888739 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.51 0.38 1.48e-5 Menarche (age at onset); TGCT cis rs514406 0.525 rs269291 chr1:53189297 C/T cg16325326 chr1:53192061 ZYG11B 0.89 12.69 0.75 3.63e-24 Monocyte count; TGCT cis rs875971 0.660 rs1860470 chr7:66103694 G/C cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs240764 0.658 rs10457077 chr6:101196767 C/T cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs4325129 0.651 rs2028933 chr1:159501125 G/A cg07417683 chr1:159440267 NA 0.37 4.64 0.38 8.54e-6 Obesity-related traits; TGCT cis rs10823500 0.777 rs10999196 chr10:71982305 T/C cg04118878 chr10:71993077 PPA1 0.57 5.25 0.43 6.25e-7 Blood protein levels; TGCT cis rs1371867 0.875 rs1788168 chr8:101324960 G/T cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg12310025 chr6:25882481 NA -1.1 -14.2 -0.79 9.06e-28 Urate levels; TGCT cis rs2235642 0.685 rs2667681 chr16:1653206 C/T cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs6921919 0.515 rs1339898 chr6:28395506 C/T cg09682330 chr6:28411287 ZSCAN23 -0.48 -4.5 -0.37 1.54e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs8062405 1.000 rs62036617 chr16:28827498 T/C cg09754948 chr16:28834200 ATXN2L 0.62 4.68 0.39 7.4e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg12756686 chr19:29218302 NA 0.77 6.61 0.51 1.01e-9 Methadone dose in opioid dependence; TGCT trans rs2688608 0.672 rs2688621 chr10:75687849 C/T cg13918328 chr10:52500089 ASAH2B 0.66 6.86 0.52 2.86e-10 Inflammatory bowel disease; TGCT cis rs7020830 0.830 rs308499 chr9:37348059 C/G cg14294708 chr9:37120828 ZCCHC7 1.02 12.67 0.75 4.19e-24 Schizophrenia; TGCT cis rs1008375 1.000 rs13149474 chr4:17688582 G/A cg10189774 chr4:17578691 LAP3 -0.61 -5.25 -0.43 6.52e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs911555 0.755 rs11627446 chr14:103946450 G/C cg12935359 chr14:103987150 CKB -0.33 -4.59 -0.38 1.07e-5 Intelligence (multi-trait analysis); TGCT cis rs9911578 0.835 rs10853006 chr17:56489076 G/A cg12560992 chr17:57184187 TRIM37 -0.76 -8.7 -0.62 1.68e-14 Intelligence (multi-trait analysis); TGCT cis rs763121 0.853 rs1013338 chr22:38974154 C/A cg06022373 chr22:39101656 GTPBP1 0.84 8.71 0.62 1.64e-14 Menopause (age at onset); TGCT cis rs826838 0.935 rs1486357 chr12:39073675 A/G cg13010199 chr12:38710504 ALG10B 0.83 6.9 0.53 2.4e-10 Heart rate; TGCT cis rs6933660 0.745 rs9322320 chr6:151751908 C/G cg17179660 chr6:151773299 C6orf211;RMND1 -0.53 -4.81 -0.4 4.28e-6 Menarche (age at onset); TGCT cis rs6964587 1.000 rs6960867 chr7:91712698 A/G cg22709100 chr7:91322751 NA 0.29 4.67 0.39 7.85e-6 Breast cancer; TGCT cis rs2841277 0.708 rs4465542 chr14:105407798 A/G cg21017887 chr14:105400489 NA 0.33 4.77 0.39 5.12e-6 Rheumatoid arthritis; TGCT cis rs1075232 1.000 rs1075232 chr15:31741216 C/A cg01030201 chr15:31746330 NA -1.03 -5.61 -0.45 1.27e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs13191362 1.000 rs55822577 chr6:163069710 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.03 7.35 0.55 2.37e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs2727020 0.595 rs10839281 chr11:49483373 A/C cg15704280 chr7:45808275 SEPT13 -0.77 -9.09 -0.63 2e-15 Coronary artery disease; TGCT cis rs9372253 0.818 rs2207360 chr6:110706337 G/C cg01119278 chr6:110721349 DDO -0.3 -4.79 -0.4 4.71e-6 Platelet distribution width; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg04234412 chr22:24373322 LOC391322 -0.91 -8.04 -0.59 5.92e-13 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs477895 1.000 rs2276014 chr11:64081445 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.19 0.42 8.41e-7 Mean platelet volume; TGCT cis rs36051895 0.632 rs57698263 chr9:5143262 G/A cg02405213 chr9:5042618 JAK2 -0.72 -10.05 -0.67 9.59e-18 Pediatric autoimmune diseases; TGCT cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs9611519 0.929 rs73174657 chr22:41434158 G/A cg03806693 chr22:41940476 POLR3H -0.7 -6.22 -0.49 6.88e-9 Neuroticism; TGCT cis rs9341808 0.667 rs742833 chr6:80921446 C/T cg08355045 chr6:80787529 NA 0.29 4.88 0.4 3.2e-6 Sitting height ratio; TGCT cis rs523522 0.962 rs10849759 chr12:120994488 T/A cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs4822044 0.568 rs1883370 chr22:42143740 C/A cg13695892 chr22:41940480 POLR3H 0.83 7.85 0.58 1.63e-12 Cannabis dependence symptom count; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg10150615 chr22:24372951 LOC391322 0.84 7.28 0.55 3.42e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT trans rs17685 0.672 rs6465011 chr7:75811297 T/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.78 0.62 1.12e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs17401966 0.838 rs4846197 chr1:10282166 G/A cg19773385 chr1:10388646 KIF1B -0.22 -4.78 -0.39 4.79e-6 Hepatocellular carcinoma; TGCT cis rs1577917 1.000 rs12215903 chr6:86675028 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.48 -0.44 2.27e-7 Response to antipsychotic treatment; TGCT cis rs981844 0.712 rs4302444 chr4:154745663 A/G cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs17376456 0.825 rs66564678 chr5:93165894 C/T cg25358565 chr5:93447407 FAM172A 0.91 7.39 0.55 1.88e-11 Diabetic retinopathy; TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs709400 0.633 rs10135868 chr14:104004147 T/C cg26031613 chr14:104095156 KLC1 0.87 9.64 0.65 9.63e-17 Body mass index; TGCT trans rs3780486 0.881 rs10738906 chr9:33135634 T/C cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT cis rs62402013 1 rs62402013 chr6:26915000 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 0.47 5.04 0.41 1.62e-6 Schizophrenia; TGCT cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.71 0.46 7.78e-8 Bipolar disorder; TGCT cis rs72615157 0.595 rs112241539 chr7:99847237 C/T cg00814883 chr7:100076585 TSC22D4 -0.59 -5.7 -0.46 8.45e-8 Lung function (FEV1/FVC); TGCT cis rs6496667 0.586 rs7162687 chr15:90889323 C/T cg22089800 chr15:90895588 ZNF774 -0.63 -5.6 -0.45 1.32e-7 Rheumatoid arthritis; TGCT cis rs1903068 1.000 rs73236109 chr4:56007425 C/T cg09978860 chr4:56023921 NA 0.59 6.74 0.52 5.22e-10 Endometriosis; TGCT cis rs911555 0.755 rs34411783 chr14:103900639 G/A cg23461800 chr14:103021989 NA -0.37 -4.73 -0.39 5.89e-6 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.695 rs7942055 chr11:93691063 A/C cg17595323 chr11:93583763 C11orf90 0.39 4.83 0.4 3.95e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9326248 0.953 rs488962 chr11:117072525 C/T cg16524733 chr11:117070046 TAGLN -0.32 -4.48 -0.37 1.64e-5 Blood protein levels; TGCT cis rs3087591 0.708 rs3785956 chr17:29647707 C/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.74 0.46 6.74e-8 Hip circumference; TGCT cis rs7208859 0.673 rs216435 chr17:28922737 G/T cg04154034 chr17:28927549 LRRC37B2 0.79 4.8 0.4 4.54e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17253792 0.822 rs77741349 chr14:56097462 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs9894429 0.646 rs7406825 chr17:79619188 C/T cg21028142 chr17:79581711 NPLOC4 0.29 5.91 0.47 3.09e-8 Eye color traits; TGCT cis rs4808199 0.895 rs8105094 chr19:19374061 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.14 0.42 1.03e-6 Nonalcoholic fatty liver disease; TGCT cis rs9860250 0.644 rs4928106 chr3:100763611 C/T cg05801080 chr3:100119813 LNP1;TOMM70A -0.63 -4.69 -0.39 7.18e-6 Optic disc area; TGCT cis rs711245 0.573 rs11899523 chr2:36800918 T/C cg01206211 chr2:36825736 FEZ2 0.31 4.8 0.4 4.51e-6 Height; TGCT cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg20203395 chr5:56204925 C5orf35 0.67 4.91 0.4 2.8e-6 Initial pursuit acceleration; TGCT cis rs2012796 0.785 rs61986593 chr14:81840659 G/A cg02996355 chr14:81879375 NA 0.54 5.35 0.43 4.05e-7 Night sleep phenotypes; TGCT cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs3027009 0.881 rs3026955 chr1:159144034 C/A cg11719576 chr1:158153771 CD1D -0.39 -4.52 -0.38 1.41e-5 Lean body mass and age at menarche (combined); TGCT cis rs763014 0.898 rs916414 chr16:632073 C/T cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs1008375 1.000 rs1558377 chr4:17650758 A/G cg18681998 chr4:17616180 MED28 1.06 12.43 0.74 1.57e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg06481639 chr22:41940642 POLR3H -0.61 -5.11 -0.42 1.17e-6 Vitiligo; TGCT cis rs1205863 1.000 rs1205890 chr6:11948579 G/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs7714584 1.000 rs7736554 chr5:150258308 T/C cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs4919044 0.808 rs860669 chr10:94796031 T/C cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs576982 1 rs576982 chr15:78870803 C/T cg24631222 chr15:78858424 CHRNA5 0.86 6.45 0.5 2.3e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7659604 0.539 rs2063165 chr4:122750005 A/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.32 -0.43 4.66e-7 Type 2 diabetes; TGCT cis rs514406 0.505 rs12726160 chr1:53175099 A/G cg22166914 chr1:53195759 ZYG11B 0.45 7.93 0.58 1.11e-12 Monocyte count; TGCT cis rs7216064 1.000 rs7214758 chr17:65880538 T/C cg12091567 chr17:66097778 LOC651250 -0.82 -6.39 -0.5 3.03e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6547741 0.904 rs2384659 chr2:27856793 G/A cg27432699 chr2:27873401 GPN1 0.18 4.49 0.37 1.59e-5 Oral cavity cancer; TGCT cis rs111803315 0.661 rs111908790 chr14:59999137 A/G cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs2777491 1.000 rs2730055 chr15:41735708 C/A cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.01 -0.7 4.47e-20 Ulcerative colitis; TGCT cis rs4014195 0.521 rs12576996 chr11:65580638 G/T cg27068330 chr11:65405492 SIPA1 0.61 4.86 0.4 3.55e-6 Glomerular filtration rate (creatinine);Chronic kidney disease; TGCT trans rs8073060 0.586 rs225288 chr17:33929291 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.04 -0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs4808199 0.649 rs12983940 chr19:19516431 G/A cg03709012 chr19:19516395 GATAD2A 1.01 7.94 0.58 1.02e-12 Nonalcoholic fatty liver disease; TGCT cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg06634786 chr22:41940651 POLR3H -0.74 -7.19 -0.54 5.26e-11 Vitiligo; TGCT cis rs2836974 0.897 rs36113648 chr21:40555497 G/A cg11890956 chr21:40555474 PSMG1 1.12 12.26 0.74 4.02e-23 Cognitive function; TGCT cis rs477895 0.838 rs2070765 chr11:64010085 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 6.59 0.51 1.11e-9 Mean platelet volume; TGCT cis rs6534347 0.573 rs4833837 chr4:123536963 G/A cg10583651 chr4:123538969 IL21 -0.31 -4.51 -0.38 1.49e-5 Type 1 diabetes; TGCT cis rs7246657 0.525 rs10405238 chr19:37488055 T/G cg18154014 chr19:37997991 ZNF793 0.73 4.6 0.38 1.04e-5 Coronary artery calcification; TGCT cis rs1949733 0.701 rs2631735 chr4:8476118 A/G cg13073564 chr4:8508604 NA -0.46 -4.73 -0.39 6.07e-6 Response to antineoplastic agents; TGCT cis rs890835 0.571 rs114640249 chr5:175932010 C/T cg07482766 chr5:176901844 DBN1 0.21 4.54 0.38 1.29e-5 Menopause (age at onset); TGCT cis rs826838 0.967 rs1719858 chr12:39124505 C/T cg26384229 chr12:38710491 ALG10B -0.86 -7.76 -0.57 2.68e-12 Heart rate; TGCT cis rs12762955 0.528 rs10903358 chr10:1102386 G/A cg26597838 chr10:835615 NA 0.56 6.38 0.5 3.23e-9 Response to angiotensin II receptor blocker therapy; TGCT trans rs13064411 0.591 rs7628945 chr3:113201754 A/T cg00307254 chr3:126706825 PLXNA1 0.34 6.72 0.52 5.79e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT trans rs1814175 0.615 rs10839378 chr11:49806943 C/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.22 -0.71 1.34e-20 Height; TGCT cis rs4460629 0.742 rs11264312 chr1:155075888 T/C cg23973274 chr1:155060172 NA -0.26 -4.66 -0.39 8.1e-6 Serum magnesium levels; TGCT cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg22121687 chr7:65037720 NA -0.78 -4.69 -0.39 7.07e-6 Diabetic kidney disease; TGCT cis rs797680 0.856 rs797681 chr1:93717746 T/C cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2067615 0.560 rs10861671 chr12:107220927 T/C cg15890332 chr12:107067104 RFX4 0.29 5.83 0.46 4.51e-8 Heart rate; TGCT cis rs854765 0.534 rs7207461 chr17:17949789 T/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs10501293 0.746 rs4755691 chr11:43054865 C/T cg03447554 chr11:43094025 NA 0.45 6.58 0.51 1.2e-9 Cognitive performance; TGCT cis rs8064299 0.565 rs12453550 chr17:72786086 G/T cg25054828 chr17:72772726 NAT9;TMEM104 0.93 10.47 0.69 9.02e-19 Monocyte count; TGCT cis rs910316 1.000 rs7303 chr14:75520065 T/C cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs79349575 0.715 rs55724082 chr17:47017879 G/A cg07967210 chr17:47022446 SNF8 0.44 6.14 0.48 1.01e-8 Type 2 diabetes; TGCT cis rs9633740 1.000 rs1870138 chr10:82269611 A/G cg01528321 chr10:82214614 TSPAN14 0.98 8.15 0.59 3.34e-13 Post bronchodilator FEV1; TGCT cis rs2115630 1.000 rs56074163 chr15:85351332 C/T cg17173187 chr15:85201210 NMB -0.39 -4.78 -0.39 4.83e-6 P wave terminal force; TGCT cis rs2836974 0.563 rs6517522 chr21:40553845 T/C cg17971929 chr21:40555470 PSMG1 0.65 5.98 0.47 2.18e-8 Cognitive function; TGCT cis rs9291683 0.575 rs3756223 chr4:10105797 C/T cg11266682 chr4:10021025 SLC2A9 0.49 5.38 0.44 3.56e-7 Bone mineral density; TGCT cis rs1867631 1.000 rs10789212 chr1:67128155 G/A cg13052034 chr1:66999238 SGIP1 0.57 4.87 0.4 3.32e-6 Menopause (age at onset); TGCT cis rs13242816 0.881 rs17138706 chr7:116109019 A/G cg16553024 chr7:116138462 CAV2 -0.44 -4.53 -0.38 1.34e-5 P wave duration; TGCT cis rs6500602 0.727 rs2058811 chr16:4575162 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 6.12 0.48 1.15e-8 Schizophrenia; TGCT cis rs710216 0.912 rs11537640 chr1:43424519 T/G cg03128534 chr1:43423976 SLC2A1 0.59 4.54 0.38 1.33e-5 Red cell distribution width; TGCT cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs9916302 0.660 rs4795367 chr17:37608843 G/C cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs17401966 0.558 rs12128374 chr1:10426417 G/A cg19773385 chr1:10388646 KIF1B -0.22 -5.27 -0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs62244186 0.516 rs11922470 chr3:44777795 C/T cg09333631 chr3:44802604 KIF15;KIAA1143 -0.46 -4.86 -0.4 3.49e-6 Depressive symptoms; TGCT cis rs595982 0.546 rs12461075 chr19:49399821 G/A cg15549821 chr19:49342101 PLEKHA4 -0.41 -5.3 -0.43 5.08e-7 Red cell distribution width; TGCT trans rs9329221 0.741 rs9650622 chr8:9804292 G/T cg15556689 chr8:8085844 FLJ10661 -0.82 -7.75 -0.57 2.83e-12 Neuroticism; TGCT cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs10782582 0.609 rs80059220 chr1:76279112 G/T cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs72781680 0.898 rs17509001 chr2:24021231 T/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs3733585 0.781 rs57250714 chr4:9984529 C/T cg00071950 chr4:10020882 SLC2A9 0.57 6.82 0.52 3.56e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg11494091 chr17:61959527 GH2 0.42 7.33 0.55 2.54e-11 Height; TGCT cis rs7156960 0.898 rs12884039 chr14:76717953 A/G cg13981132 chr14:76734493 NA 0.29 4.48 0.37 1.7e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs36051895 0.623 rs62541543 chr9:5042082 G/A cg02405213 chr9:5042618 JAK2 -0.76 -10.28 -0.68 2.59e-18 Pediatric autoimmune diseases; TGCT cis rs6570726 0.791 rs435671 chr6:145881215 A/G cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.505 rs269287 chr1:53168842 T/C cg08859206 chr1:53392774 SCP2 -0.34 -4.77 -0.39 5.09e-6 Monocyte count; TGCT cis rs9894429 0.816 rs7406040 chr17:79597583 A/C cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT cis rs2742417 1.000 rs2742454 chr3:45766222 T/A cg04837898 chr3:45731254 SACM1L -0.51 -5.27 -0.43 5.85e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs651907 0.557 rs13099674 chr3:101489629 G/A cg12386194 chr3:101231763 SENP7 0.48 4.7 0.39 6.71e-6 Colorectal cancer; TGCT cis rs12477438 0.798 rs12473029 chr2:99637961 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.66 -0.61 2.13e-14 Chronic sinus infection; TGCT cis rs709400 0.633 rs3783395 chr14:103895020 T/C cg26031613 chr14:104095156 KLC1 0.84 9.31 0.64 5.77e-16 Body mass index; TGCT cis rs4665809 0.877 rs35224700 chr2:26298037 T/C cg22920501 chr2:26401640 FAM59B 0.74 5.78 0.46 5.68e-8 Gut microbiome composition (summer); TGCT cis rs2456568 0.548 rs6483280 chr11:93661592 T/C cg26875233 chr11:93583750 C11orf90 -0.44 -5.41 -0.44 3.08e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9486715 0.867 rs4839834 chr6:96882109 C/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs28374715 0.532 rs1899 chr15:41689232 C/T cg18705301 chr15:41695430 NDUFAF1 -0.94 -16.61 -0.83 2.59e-33 Ulcerative colitis; TGCT cis rs12497850 0.931 rs6414613 chr3:49035885 C/T cg05785598 chr3:49045655 WDR6 0.36 4.8 0.4 4.57e-6 Parkinson's disease; TGCT cis rs7095607 0.560 rs2634709 chr10:69925789 C/T cg18986048 chr10:69913749 MYPN 0.54 5.83 0.46 4.48e-8 Lung function (FVC); TGCT cis rs56114371 0.530 rs2056923 chr6:27689939 T/C cg10876282 chr6:28092338 ZSCAN16 0.66 5.0 0.41 1.93e-6 Breast cancer; TGCT cis rs3771570 1.000 rs62193207 chr2:242318501 G/C cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs3845702 0.736 rs6727890 chr2:180832675 T/C cg01881094 chr2:180872142 CWC22 -1.07 -6.88 -0.53 2.6e-10 Schizophrenia; TGCT cis rs910316 1.000 rs10149880 chr14:75633008 A/G cg23033748 chr14:75592666 NEK9 -0.28 -4.77 -0.39 4.98e-6 Height; TGCT cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg13695892 chr22:41940480 POLR3H 0.86 8.23 0.59 2.23e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs727505 0.954 rs1009450 chr7:124628723 C/G cg23710748 chr7:124431027 NA -0.27 -4.58 -0.38 1.11e-5 Lewy body disease; TGCT cis rs78487399 0.808 rs7561287 chr2:43689071 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.59 0.38 1.09e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6840360 1.000 rs6834095 chr4:152603278 C/T cg17479576 chr4:152424074 FAM160A1 -0.45 -4.87 -0.4 3.29e-6 Intelligence (multi-trait analysis); TGCT cis rs933688 1.000 rs1964292 chr5:90743608 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.47 0.61 6.09e-14 Smoking behavior; TGCT cis rs769267 0.965 rs2074299 chr19:19380646 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs896854 0.846 rs2340584 chr8:95916811 A/G cg09323728 chr8:95962352 TP53INP1 -0.49 -6.32 -0.49 4.31e-9 Type 2 diabetes; TGCT trans rs4650994 0.789 rs2811300 chr1:178590394 T/C cg05059571 chr16:84539110 KIAA1609 0.41 7.51 0.56 1e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs78707713 0.560 rs61848436 chr10:71247714 C/T cg14388049 chr10:71211838 TSPAN15 -0.4 -4.76 -0.39 5.31e-6 Venous thromboembolism; TGCT trans rs2624839 0.679 rs2624835 chr3:50209049 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.78 6.93 0.53 2.05e-10 Intelligence (multi-trait analysis); TGCT cis rs33794 1.000 rs33794 chr3:45300605 C/T cg18645101 chr3:44551900 NA -0.51 -4.46 -0.37 1.8e-5 Lung function (forced expiratory volume in 1 second); TGCT trans rs10953454 1.000 rs10243336 chr7:104494560 C/A cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs9611519 0.639 rs7289989 chr22:41476799 A/C cg03806693 chr22:41940476 POLR3H -0.5 -4.47 -0.37 1.72e-5 Neuroticism; TGCT cis rs10751667 0.666 rs7934963 chr11:957220 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.06 -0.59 5.6e-13 Alzheimer's disease (late onset); TGCT cis rs2549003 1.000 rs7734334 chr5:131815004 C/A cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs4851266 1.000 rs999052 chr2:100836106 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.41 -0.44 3.1e-7 Educational attainment; TGCT cis rs11105298 0.891 rs10858872 chr12:89872932 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs62103177 0.535 rs62101568 chr18:77934671 G/A cg07235805 chr18:78004237 PARD6G 0.54 5.03 0.41 1.67e-6 Opioid sensitivity; TGCT cis rs10782582 0.609 rs1770882 chr1:76411549 G/A cg10523679 chr1:76189770 ACADM -0.57 -5.14 -0.42 1.04e-6 Daytime sleep phenotypes; TGCT cis rs7647973 0.961 rs4955443 chr3:49286618 T/G cg07690219 chr3:49449608 TCTA;RHOA -0.55 -4.48 -0.37 1.68e-5 Menarche (age at onset); TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg11141652 chr22:24348549 GSTTP1 0.33 4.54 0.38 1.29e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12477438 0.765 rs6542846 chr2:99563654 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -7.21 -0.54 4.82e-11 Chronic sinus infection; TGCT cis rs2033711 0.870 rs7408188 chr19:58939389 T/G cg04608855 chr19:58913158 NA 0.58 5.76 0.46 6.2e-8 Uric acid clearance; TGCT cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg11301795 chr4:187892539 NA -0.3 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7582180 0.676 rs10048665 chr2:100933085 A/G cg14675211 chr2:100938903 LONRF2 0.53 5.24 0.43 6.82e-7 Intelligence (multi-trait analysis); TGCT cis rs7113874 0.569 rs10160430 chr11:8599876 G/T cg14521421 chr11:8862019 ST5 -0.28 -4.44 -0.37 1.96e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs9788682 0.706 rs924840 chr15:78731808 A/T cg24631222 chr15:78858424 CHRNA5 0.63 4.67 0.39 7.67e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9419702 0.568 rs9419635 chr10:133546164 C/T cg23460707 chr10:133558971 NA 0.44 4.94 0.41 2.52e-6 Survival in rectal cancer; TGCT cis rs7208859 0.623 rs73269974 chr17:29112384 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3733585 0.783 rs13148371 chr4:10032561 C/T cg00071950 chr4:10020882 SLC2A9 0.68 8.84 0.62 7.71e-15 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12220238 1.000 rs10824106 chr10:75958408 C/T cg19889307 chr10:75911429 ADK;AP3M1 -1.03 -6.03 -0.48 1.78e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg06634786 chr22:41940651 POLR3H -0.72 -6.68 -0.51 7.15e-10 Vitiligo; TGCT cis rs9393692 0.905 rs6940237 chr6:26282322 T/C cg05868516 chr6:26286170 HIST1H4H 0.63 5.91 0.47 3.02e-8 Educational attainment; TGCT cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg13395646 chr4:1353034 KIAA1530 -0.47 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs9916302 0.904 rs11867312 chr17:37597748 C/T cg15445000 chr17:37608096 MED1 0.33 4.78 0.39 4.93e-6 Glomerular filtration rate (creatinine); TGCT cis rs2228479 0.541 rs12918575 chr16:89811151 A/G cg26513180 chr16:89883248 FANCA 0.78 4.54 0.38 1.32e-5 Skin colour saturation; TGCT trans rs629535 0.814 rs545720 chr8:70063370 T/C cg21567404 chr3:27674614 NA 0.54 8.61 0.61 2.81e-14 Dupuytren's disease; TGCT cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg03264133 chr6:25882463 NA 0.86 8.5 0.61 5.01e-14 Blood metabolite levels; TGCT cis rs56309584 0.715 rs3027246 chr17:8131223 C/T cg08322244 chr17:8066669 VAMP2 -0.57 -5.26 -0.43 6.01e-7 Initial pursuit acceleration; TGCT cis rs3087591 1.000 rs4795579 chr17:29458682 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 7.25 0.55 3.92e-11 Hip circumference; TGCT trans rs797680 0.856 rs12118262 chr1:93651547 C/T cg27528825 chr2:159282178 CCDC148 0.34 6.65 0.51 8.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1372520 0.684 rs2572318 chr4:90718719 C/T cg20003494 chr4:90757398 SNCA -0.65 -4.54 -0.38 1.34e-5 Neuroticism; TGCT cis rs8077577 0.895 rs62072464 chr17:18108314 T/C cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs12210905 0.688 rs114157955 chr6:27329878 C/T cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs4478037 0.822 rs9863331 chr3:33123235 G/T cg19404215 chr3:33155277 CRTAP 0.98 5.13 0.42 1.1e-6 Major depressive disorder; TGCT cis rs7044106 0.708 rs2416760 chr9:123374639 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.55 5.99 0.47 2.07e-8 Hip circumference adjusted for BMI; TGCT cis rs713587 0.520 rs1530016 chr2:25305756 C/T cg01884057 chr2:25150051 NA -0.26 -4.89 -0.4 3.12e-6 Body mass index in non-asthmatics; TGCT cis rs2153535 0.580 rs1855769 chr6:8473095 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg10295955 chr4:187884368 NA -0.99 -15.24 -0.81 3.38e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs78456975 1.000 rs13422995 chr2:1553554 C/A cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7772486 0.875 rs2814866 chr6:146339414 C/A cg23711669 chr6:146136114 FBXO30 0.84 9.13 0.63 1.59e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs9807989 0.801 rs4851566 chr2:102972799 G/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs12378800 0.520 rs734769 chr9:100844198 C/T cg00089695 chr9:101746445 COL15A1 -0.32 -4.45 -0.37 1.89e-5 Alzheimer disease and age of onset; TGCT cis rs17221829 0.733 rs117029483 chr11:89365918 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.23e-9 Blood metabolite levels; TGCT cis rs4665809 1.000 rs4665308 chr2:26330514 C/A cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs801193 1.000 rs62466794 chr7:66191579 G/A cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg17264618 chr3:40429014 ENTPD3 -0.31 -4.59 -0.38 1.08e-5 Renal cell carcinoma; TGCT cis rs7940866 0.774 rs10894292 chr11:130820757 C/T cg12179176 chr11:130786555 SNX19 0.56 5.46 0.44 2.54e-7 Schizophrenia; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg00080972 chr5:178986291 RUFY1 0.59 7.71 0.57 3.57e-12 Lung cancer; TGCT cis rs7267979 0.934 rs2257464 chr20:25265872 C/T cg16686733 chr20:25566563 NINL 0.58 5.83 0.46 4.44e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7769051 1.000 rs73554431 chr6:133129922 T/G cg22852734 chr6:133119734 C6orf192 1.23 7.09 0.54 9.13e-11 Type 2 diabetes nephropathy; TGCT cis rs12368653 0.584 rs7295422 chr12:58099736 G/A cg12615879 chr12:58013172 SLC26A10 0.49 5.9 0.47 3.27e-8 Multiple sclerosis; TGCT cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg12310025 chr6:25882481 NA 0.49 5.12 0.42 1.15e-6 Blood metabolite levels; TGCT cis rs1348850 0.914 rs1374437 chr2:178363423 T/C cg22681709 chr2:178499509 PDE11A -0.35 -4.57 -0.38 1.18e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7267979 1.000 rs11087521 chr20:25440648 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.03 -14.96 -0.8 1.51e-29 Prudent dietary pattern; TGCT cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.6e-9 Bipolar disorder; TGCT trans rs10506458 1.000 rs12425932 chr12:63410497 C/A cg22491629 chr6:157744540 C6orf35 -0.99 -8.58 -0.61 3.18e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs10836699 0.635 rs999242 chr11:37201401 C/G cg18520238 chr11:36422557 PRR5L -0.18 -4.48 -0.37 1.66e-5 Low high density lipoprotein cholesterol levels; TGCT cis rs1971762 0.509 rs1247955 chr12:53964133 G/T cg16917193 chr12:54089295 NA -1.04 -11.02 -0.7 4.2e-20 Height; TGCT cis rs1577917 0.958 rs34765423 chr6:86484448 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.46 -0.44 2.47e-7 Response to antipsychotic treatment; TGCT cis rs4654899 0.865 rs6665549 chr1:21475884 G/C cg01072550 chr1:21505969 NA -0.47 -6.96 -0.53 1.74e-10 Superior frontal gyrus grey matter volume; TGCT cis rs10782582 0.545 rs111927462 chr1:76195422 A/G cg10523679 chr1:76189770 ACADM -0.66 -6.69 -0.52 6.7e-10 Daytime sleep phenotypes; TGCT cis rs4819052 0.840 rs914217 chr21:46698299 A/G cg06618935 chr21:46677482 NA -0.38 -4.96 -0.41 2.28e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.71 0.52 6.11e-10 Bipolar disorder; TGCT cis rs6921919 0.609 rs9468357 chr6:28342053 T/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.37 -0.43 3.8e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs72949976 0.584 rs12467619 chr2:214022933 T/C cg08319019 chr2:214017104 IKZF2 0.84 8.41 0.6 8.42e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs35306767 0.953 rs11253517 chr10:970524 A/G cg18964960 chr10:1102726 WDR37 -0.57 -4.46 -0.37 1.82e-5 Eosinophil percentage of granulocytes; TGCT cis rs1552244 0.510 rs13075308 chr3:10034925 G/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs4285214 0.715 rs12515071 chr5:124031011 C/T cg15082166 chr5:124005151 ZNF608 0.36 4.85 0.4 3.63e-6 Survival in pancreatic cancer; TGCT cis rs6964587 1.000 rs4727266 chr7:91570129 C/T cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs3784262 0.669 rs12909979 chr15:58241022 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.01 -0.47 1.94e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs57221529 0.766 rs12521988 chr5:556421 C/T cg09021430 chr5:549028 NA -0.4 -5.46 -0.44 2.44e-7 Lung disease severity in cystic fibrosis; TGCT cis rs9467773 1.000 rs9393729 chr6:26514166 C/T cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs5750830 0.649 rs5757657 chr22:39798429 G/T cg05872129 chr22:39784769 NA -1.01 -11.68 -0.72 1.05e-21 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs7730700 chr5:264713 G/A cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs926938 0.520 rs2007231 chr1:115266306 C/T cg12756093 chr1:115239321 AMPD1 -0.42 -5.2 -0.42 7.84e-7 Autism; TGCT cis rs1865760 1.000 rs9348698 chr6:25929689 T/A cg16482183 chr6:26056742 HIST1H1C 0.51 4.57 0.38 1.17e-5 Height; TGCT cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.62 -0.38 9.52e-6 Obesity-related traits; TGCT trans rs629535 0.814 rs654452 chr8:70074344 C/G cg21567404 chr3:27674614 NA 0.57 9.09 0.63 1.94e-15 Dupuytren's disease; TGCT cis rs4851254 0.961 rs11692215 chr2:100746573 C/T cg04109781 chr2:100722022 AFF3 0.42 4.49 0.37 1.6e-5 Intelligence (multi-trait analysis); TGCT cis rs16866061 1.000 rs16866061 chr2:225439844 A/G cg12698349 chr2:225449008 CUL3 0.97 10.26 0.68 2.88e-18 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs7605378 0.658 rs4673507 chr2:200710167 G/C cg19045956 chr2:200819837 C2orf60;C2orf47 0.51 4.89 0.4 3.11e-6 Osteoporosis; TGCT cis rs478304 0.817 rs524475 chr11:65518065 T/A cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.01e-7 Acne (severe); TGCT cis rs2361710 0.704 rs12937349 chr17:78120320 G/C cg09238746 chr17:78121135 EIF4A3 -0.78 -7.37 -0.55 2.1e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs2010099 0.759 rs78365741 chr3:124294281 A/C cg04915618 chr3:124304960 KALRN 0.53 4.77 0.39 5.16e-6 Thyroid peroxidase antibody levels; TGCT cis rs290268 0.874 rs290994 chr9:93559515 T/A cg02608019 chr9:93564028 SYK 0.46 4.74 0.39 5.69e-6 Platelet count; TGCT cis rs66561647 0.661 rs7835090 chr8:128940177 A/C cg11792826 chr8:129160931 MIR1208 0.22 4.96 0.41 2.25e-6 Hemoglobin concentration; TGCT cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg00814883 chr7:100076585 TSC22D4 -0.86 -8.1 -0.59 4.49e-13 Platelet count; TGCT cis rs1933488 0.898 rs11155895 chr6:153421545 C/A cg24028809 chr6:153414101 RGS17 0.2 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs4820539 1.000 rs916584 chr22:23469433 A/G cg14186256 chr22:23484241 RTDR1 0.98 12.28 0.74 3.5e-23 Bone mineral density; TGCT cis rs2050392 0.767 rs10763787 chr10:30700753 G/A cg18806716 chr10:30721971 MAP3K8 0.69 9.36 0.64 4.5e-16 Inflammatory bowel disease; TGCT cis rs7178424 0.616 rs9920945 chr15:62136913 G/A cg00456672 chr15:62358751 C2CD4A -0.31 -4.71 -0.39 6.66e-6 Height; TGCT cis rs7954584 0.504 rs10840633 chr12:122377511 A/T cg22618164 chr12:122356400 WDR66 0.66 6.17 0.48 9.08e-9 Mean corpuscular volume; TGCT cis rs3820068 0.705 rs4646110 chr1:15817318 A/T cg05660106 chr1:15850417 CASP9 1.15 14.12 0.79 1.41e-27 Systolic blood pressure; TGCT cis rs7552404 0.889 rs1250874 chr1:76190978 A/G cg03433033 chr1:76189801 ACADM 0.77 9.35 0.64 4.77e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.830 rs6811940 chr4:98777898 G/A cg18180107 chr4:99064573 C4orf37 0.53 5.05 0.41 1.51e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg02487422 chr3:49467188 NICN1 0.54 5.2 0.42 8.11e-7 Menarche (age at onset); TGCT cis rs3749237 0.964 rs10865959 chr3:49891002 G/C cg03060546 chr3:49711283 APEH 0.7 6.71 0.52 6.05e-10 Resting heart rate; TGCT cis rs28595532 0.920 rs116305850 chr4:119779892 A/G cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs12911832 0.727 rs682619 chr15:59098773 T/C cg05156742 chr15:59063176 FAM63B 0.55 5.33 0.43 4.49e-7 Schizophrenia; TGCT cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg07092213 chr7:1199455 ZFAND2A -0.43 -4.62 -0.38 9.36e-6 Longevity;Endometriosis; TGCT cis rs137603 0.562 rs137644 chr22:39728139 A/G cg17798944 chr22:39715225 SNORD43;RPL3 -0.64 -6.77 -0.52 4.55e-10 Primary biliary cholangitis; TGCT cis rs9527 0.637 rs11191424 chr10:104625886 G/A cg15744005 chr10:104629667 AS3MT -0.49 -6.35 -0.5 3.65e-9 Arsenic metabolism; TGCT cis rs2120019 1.000 rs8036197 chr15:75370232 T/C cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs6089829 0.962 rs6122347 chr20:61661866 C/T cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.505 rs12726160 chr1:53175099 A/G cg24675658 chr1:53192096 ZYG11B -0.79 -9.45 -0.65 2.78e-16 Monocyte count; TGCT cis rs9913156 0.793 rs72835643 chr17:4573612 G/A cg19197139 chr17:4613644 ARRB2 0.88 8.13 0.59 3.75e-13 Lymphocyte counts; TGCT cis rs7267979 0.966 rs6037083 chr20:25290543 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs1876192 chr4:98727555 T/C cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs8180040 0.726 rs6785790 chr3:47146932 C/T cg27129171 chr3:47204927 SETD2 0.74 9.88 0.66 2.48e-17 Colorectal cancer; TGCT cis rs9921222 0.509 rs3743883 chr16:404750 T/C cg12437481 chr16:420112 MRPL28 -0.48 -4.6 -0.38 1.04e-5 Bone mineral density (spine);Bone mineral density; TGCT trans rs3780486 0.505 rs10813959 chr9:33166234 C/T cg20290983 chr6:43655470 MRPS18A -0.79 -8.48 -0.61 5.57e-14 IgG glycosylation; TGCT cis rs7552404 0.731 rs12090849 chr1:76400261 A/G cg03433033 chr1:76189801 ACADM 0.71 6.77 0.52 4.62e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.08e-7 Lymphocyte counts; TGCT cis rs13088281 1.000 rs13088281 chr3:53147576 A/C cg15956490 chr3:53032818 SFMBT1 -0.58 -7.12 -0.54 7.59e-11 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10791097 0.694 rs10894273 chr11:130742155 G/T cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1692580 0.777 rs12136830 chr1:2189196 A/T cg21194808 chr1:2205498 SKI 0.29 5.78 0.46 5.71e-8 Coronary artery disease; TGCT cis rs11676348 0.846 rs11677534 chr2:219007060 T/C cg00012203 chr2:219082015 ARPC2 -0.52 -4.84 -0.4 3.78e-6 Ulcerative colitis; TGCT cis rs1371867 0.846 rs1660328 chr8:101303450 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs4285028 0.747 rs4048699 chr3:121404483 A/G cg17324707 chr3:122103153 FAM162A;CCDC58 0.62 4.55 0.38 1.28e-5 Multiple sclerosis; TGCT cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6693567 0.565 rs1313569 chr1:150344171 G/A cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs9611565 0.559 rs132771 chr22:42025350 A/G cg17554472 chr22:41940697 POLR3H 0.5 5.26 0.43 6.02e-7 Vitiligo; TGCT cis rs17221829 0.702 rs72969198 chr11:89357607 T/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs1903068 0.853 rs73236111 chr4:56019068 A/C cg01777861 chr4:56023843 NA 0.54 6.05 0.48 1.6e-8 Endometriosis; TGCT cis rs17331151 0.573 rs2240916 chr3:52859212 T/A cg27565382 chr3:53032988 SFMBT1 0.4 5.05 0.41 1.57e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7582180 0.764 rs12622318 chr2:100927375 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.91 -0.4 2.81e-6 Intelligence (multi-trait analysis); TGCT cis rs11785400 0.612 rs10110864 chr8:143750072 A/G cg10596483 chr8:143751796 JRK 0.58 6.04 0.48 1.64e-8 Schizophrenia; TGCT cis rs916888 0.773 rs538628 chr17:44787313 G/C cg17911788 chr17:44343683 NA -0.65 -6.61 -0.51 1.04e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2288884 0.690 rs11666341 chr19:52601399 G/A cg13540795 chr19:52551618 ZNF432 -0.7 -6.03 -0.48 1.78e-8 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs919433 0.617 rs34632716 chr2:198542619 C/T cg00792783 chr2:198669748 PLCL1 -0.55 -5.04 -0.41 1.62e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs6460942 1.000 rs118083671 chr7:12466036 C/T cg06484146 chr7:12443880 VWDE -0.58 -5.62 -0.45 1.21e-7 Coronary artery disease; TGCT cis rs887829 0.588 rs4663971 chr2:234674252 C/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.49 -0.37 1.63e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs7845219 0.597 rs7002058 chr8:95873993 G/C cg13393036 chr8:95962371 TP53INP1 -0.49 -5.86 -0.47 3.92e-8 Type 2 diabetes; TGCT cis rs1008375 1.000 rs4698200 chr4:17657051 G/A cg10189774 chr4:17578691 LAP3 0.58 5.26 0.43 6.24e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3771570 1.000 rs62193208 chr2:242322430 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT trans rs210152 0.588 rs1755040 chr6:33495175 A/C cg22108809 chr5:56777663 ACTBL2 -0.54 -6.67 -0.51 7.44e-10 Schizophrenia; TGCT cis rs12421382 0.543 rs10890996 chr11:109328421 A/G cg16359550 chr11:109292809 C11orf87 -0.69 -7.9 -0.58 1.29e-12 Schizophrenia; TGCT cis rs7208859 0.673 rs11080138 chr17:29224542 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs35264875 0.898 rs55648928 chr11:68861591 G/T cg02660097 chr11:68866761 NA 0.32 4.61 0.38 9.94e-6 Blond vs. brown hair color; TGCT cis rs10823500 0.636 rs7082396 chr10:71945511 C/A cg02100629 chr10:71892760 AIFM2 -0.45 -4.85 -0.4 3.62e-6 Blood protein levels; TGCT cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs9611565 0.546 rs132793 chr22:42063681 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.2 0.42 8.09e-7 Vitiligo; TGCT cis rs2404602 0.536 rs1587381 chr15:76769620 G/A cg22467129 chr15:76604101 ETFA -0.48 -5.9 -0.47 3.27e-8 Blood metabolite levels; TGCT cis rs6460942 1.000 rs73053527 chr7:12313008 C/A cg06484146 chr7:12443880 VWDE -0.57 -4.87 -0.4 3.35e-6 Coronary artery disease; TGCT cis rs9549260 0.755 rs3892360 chr13:41184078 C/G cg21288729 chr13:41239152 FOXO1 1.01 10.14 0.67 5.8e-18 Red blood cell count; TGCT cis rs9859260 0.710 rs41298097 chr3:195779155 C/T cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs13242816 1.000 rs56275709 chr7:116108489 A/G cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT cis rs854765 0.647 rs2974999 chr17:17997547 T/G cg04398451 chr17:18023971 MYO15A -0.38 -6.61 -0.51 1.04e-9 Total body bone mineral density; TGCT cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg09323728 chr8:95962352 TP53INP1 -0.52 -6.71 -0.52 6.14e-10 Type 2 diabetes; TGCT cis rs6831352 0.734 rs1453872 chr4:100022482 G/A cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 7.81e-7 Alcohol dependence; TGCT cis rs8100891 0.734 rs741445 chr19:32836592 G/T cg16662424 chr19:32837316 ZNF507 -0.45 -5.43 -0.44 2.85e-7 Neuroticism; TGCT cis rs67385638 1.000 rs67385638 chr11:5290370 C/G cg12559170 chr11:5275217 HBG2 0.46 8.17 0.59 3.04e-13 Hemoglobin levels; TGCT cis rs78456975 0.607 rs72776258 chr2:1530732 C/G cg01028140 chr2:1542097 TPO -0.35 -4.48 -0.37 1.69e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7586879 0.616 rs6722587 chr2:25132192 C/A cg15423357 chr2:25149977 NA 0.52 5.03 0.41 1.65e-6 Body mass index; TGCT cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg27588902 chr6:42928151 GNMT 0.44 5.54 0.45 1.76e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg03517284 chr6:25882590 NA 0.69 7.52 0.56 9.42e-12 Blood metabolite levels; TGCT cis rs5750830 0.594 rs5757650 chr22:39778419 A/G cg05872129 chr22:39784769 NA -0.87 -9.82 -0.66 3.49e-17 Intelligence (multi-trait analysis); TGCT cis rs10788264 0.621 rs9633734 chr10:124057667 T/C cg09507567 chr10:124027408 NA 0.39 5.6 0.45 1.3e-7 Total body bone mineral density; TGCT cis rs2243480 0.901 rs3813708 chr7:65305632 C/A cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs797680 0.856 rs797672 chr1:93702119 A/T cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg16414030 chr3:133502952 NA -0.5 -6.85 -0.52 3.05e-10 Iron status biomarkers; TGCT cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg06481639 chr22:41940642 POLR3H 0.74 6.59 0.51 1.11e-9 Vitiligo; TGCT cis rs7818688 0.697 rs11784212 chr8:95976995 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs8177253 0.896 rs34252038 chr3:133490621 G/T cg08439880 chr3:133502540 NA -0.31 -5.9 -0.47 3.22e-8 Iron status biomarkers; TGCT cis rs13191362 0.872 rs13196631 chr6:163001588 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12541335 0.639 rs11779277 chr8:22200683 C/T cg02463440 chr8:22132932 PIWIL2 0.26 5.2 0.42 7.85e-7 Hypertriglyceridemia; TGCT cis rs6460942 0.908 rs75704904 chr7:12233583 G/A cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs11785693 0.862 rs62491171 chr8:4987177 G/A cg26367366 chr8:4980734 NA 0.58 4.51 0.38 1.48e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs3847687 1.000 rs11061292 chr12:131518981 T/A cg25772418 chr12:131519998 GPR133 -0.32 -5.66 -0.45 1.01e-7 Longevity; TGCT cis rs28595532 0.841 rs116093021 chr4:119763872 C/G cg14228332 chr4:119757509 SEC24D 1.3 6.62 0.51 9.62e-10 Cannabis dependence symptom count; TGCT cis rs13191362 0.935 rs35378894 chr6:163123933 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.17 0.59 3.08e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs34172651 0.517 rs200528 chr16:24759131 A/G cg06028605 chr16:24865363 SLC5A11 -0.42 -4.69 -0.39 7.14e-6 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs4824093 0.610 rs73443906 chr22:50274293 A/G cg14114931 chr22:50943910 LMF2 0.37 4.58 0.38 1.11e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2354432 0.556 rs1932979 chr1:146708912 A/G cg25205988 chr1:146714368 CHD1L -1.15 -4.8 -0.4 4.49e-6 Mitochondrial DNA levels; TGCT cis rs9399135 0.660 rs9389248 chr6:135282656 T/C cg24558204 chr6:135376177 HBS1L 0.46 4.8 0.4 4.45e-6 Red blood cell count; TGCT cis rs35306767 0.761 rs12771539 chr10:1050653 A/G cg26597838 chr10:835615 NA 0.6 6.63 0.51 9.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs9868809 0.881 rs34368826 chr3:48670827 G/T cg00383909 chr3:49044727 WDR6 0.97 5.08 0.42 1.34e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9303401 0.625 rs10515159 chr17:56802693 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs2880765 0.835 rs11074276 chr15:86030363 C/A cg13263323 chr15:86062960 AKAP13 -0.22 -4.8 -0.4 4.44e-6 Coronary artery disease; TGCT cis rs8072100 0.790 rs3760371 chr17:45695914 T/C cg08085267 chr17:45401833 C17orf57 0.46 5.01 0.41 1.82e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs644799 0.710 rs519511 chr11:95538270 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.65 0.61 2.18e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10276381 0.579 rs73072539 chr7:28146255 C/G cg23620719 chr7:28220237 JAZF1 0.74 4.5 0.37 1.56e-5 Crohn's disease; TGCT cis rs9383153 0.590 rs2072736 chr6:16328068 T/C cg23850913 chr6:15505452 JARID2 0.92 4.86 0.4 3.42e-6 Gambling; TGCT cis rs11098499 0.754 rs1980027 chr4:120251577 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9522267 0.737 rs9515448 chr13:112229526 A/T cg10483660 chr13:112241077 NA -0.29 -4.76 -0.39 5.19e-6 Hepatitis; TGCT cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs6570726 0.846 rs9399559 chr6:145945778 C/T cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs6087990 0.735 rs6058883 chr20:31365719 C/T cg13636640 chr20:31349939 DNMT3B -0.95 -12.3 -0.74 3.17e-23 Ulcerative colitis; TGCT cis rs11190604 1.000 rs2495743 chr10:102329739 G/C cg23241863 chr10:102295624 HIF1AN 0.67 4.9 0.4 2.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2832191 0.716 rs7284006 chr21:30475186 T/A cg24692254 chr21:30365293 RNF160 1.01 11.59 0.72 1.73e-21 Dental caries; TGCT cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs916888 0.610 rs199529 chr17:44837217 A/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.75 5.23 0.43 6.99e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg23149560 chr2:74406255 MOBKL1B 0.6 4.56 0.38 1.19e-5 Gestational age at birth (maternal effect); TGCT cis rs7000551 0.689 rs2449339 chr8:22387981 G/A cg12081754 chr8:22256438 SLC39A14 0.27 4.53 0.38 1.38e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs916888 0.779 rs199528 chr17:44843136 C/T cg15921436 chr17:44337874 NA 0.53 7.54 0.56 8.43e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4975709 0.589 rs931508 chr5:1861224 C/G cg04156016 chr5:1868137 NA 0.32 4.44 0.37 1.99e-5 Cardiovascular disease risk factors; TGCT cis rs6952808 0.595 rs3778984 chr7:2166514 T/C cg04267008 chr7:1944627 MAD1L1 -0.38 -5.19 -0.42 8.33e-7 Bipolar disorder and schizophrenia; TGCT cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg23758822 chr17:41437982 NA 0.73 6.94 0.53 1.93e-10 Menopause (age at onset); TGCT cis rs31872 0.521 rs246050 chr5:140326860 T/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs11096990 0.613 rs12505690 chr4:39169045 G/A cg20847110 chr4:39482781 LOC401127 0.17 4.96 0.41 2.3e-6 Cognitive function; TGCT cis rs6088580 0.602 rs6059834 chr20:33019299 A/G cg08999081 chr20:33150536 PIGU 0.29 5.66 0.45 9.92e-8 Glomerular filtration rate (creatinine); TGCT cis rs10114408 0.959 rs7863704 chr9:96638610 C/T cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2019137 0.936 rs12620738 chr2:113963739 C/T cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs17076896 0.618 rs80110795 chr13:19929059 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs710216 0.879 rs710218 chr1:43427218 A/T cg03128534 chr1:43423976 SLC2A1 0.6 4.96 0.41 2.27e-6 Red cell distribution width; TGCT cis rs9462846 0.658 rs9471970 chr6:42913646 G/A cg02353165 chr6:42928485 GNMT 0.73 5.66 0.45 1e-7 Blood protein levels; TGCT cis rs734999 0.870 rs3748825 chr1:2483270 T/C cg18854424 chr1:2615690 NA 0.46 5.36 0.43 3.98e-7 Ulcerative colitis; TGCT cis rs4689388 0.853 rs4293850 chr4:6292020 A/C cg14416269 chr4:6271139 WFS1 0.4 5.21 0.42 7.57e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1949733 1.000 rs2688223 chr4:8471398 T/C cg13073564 chr4:8508604 NA -0.48 -5.18 -0.42 8.61e-7 Response to antineoplastic agents; TGCT cis rs10504229 0.679 rs4737454 chr8:58033965 A/T cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs7647973 1.000 rs974495 chr3:49400482 T/C cg05785598 chr3:49045655 WDR6 0.39 4.65 0.39 8.28e-6 Menarche (age at onset); TGCT cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.07 12.04 0.73 1.36e-22 Height; TGCT cis rs778371 0.723 rs13001052 chr2:233683984 C/T cg08000102 chr2:233561755 GIGYF2 -0.67 -7.64 -0.57 5.21e-12 Schizophrenia; TGCT trans rs10506458 0.834 rs55966529 chr12:63384114 A/C cg22491629 chr6:157744540 C6orf35 -0.96 -8.25 -0.6 2.01e-13 Hemostatic factors and hematological phenotypes; TGCT cis rs8042680 0.554 rs59278520 chr15:91514707 G/A cg22570213 chr15:91497863 RCCD1 0.44 4.69 0.39 7.23e-6 Type 2 diabetes; TGCT cis rs5769765 0.955 rs9616368 chr22:50303533 C/G cg15316289 chr22:50310904 ALG12;CRELD2 0.41 5.84 0.46 4.39e-8 Schizophrenia; TGCT cis rs9905704 0.647 rs12940492 chr17:56954655 C/G cg05425664 chr17:57184151 TRIM37 -0.59 -4.69 -0.39 7.16e-6 Testicular germ cell tumor; TGCT cis rs17376456 0.825 rs12188163 chr5:93250608 A/G cg21475434 chr5:93447410 FAM172A -0.63 -4.86 -0.4 3.44e-6 Diabetic retinopathy; TGCT cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg19318889 chr4:1322082 MAEA 0.19 4.8 0.4 4.43e-6 Longevity; TGCT cis rs4494114 1.000 rs2147914 chr1:39352271 G/T cg25970120 chr1:39325951 RRAGC -0.6 -6.23 -0.49 6.58e-9 Blood protein levels; TGCT cis rs9291683 0.588 rs35099040 chr4:10018839 T/C cg00071950 chr4:10020882 SLC2A9 0.75 10.2 0.68 4.17e-18 Bone mineral density; TGCT cis rs453301 0.598 rs10104303 chr8:8834528 A/T cg06636001 chr8:8085503 FLJ10661 0.77 6.99 0.53 1.5e-10 Joint mobility (Beighton score); TGCT cis rs801193 0.569 rs2013908 chr7:66121069 A/T cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs2120019 0.935 rs8043181 chr15:75380424 T/C cg11632617 chr15:75315747 PPCDC -0.34 -4.88 -0.4 3.2e-6 Blood trace element (Zn levels); TGCT cis rs9325144 0.647 rs12830095 chr12:38864199 C/T cg26384229 chr12:38710491 ALG10B -0.59 -5.42 -0.44 2.98e-7 Morning vs. evening chronotype; TGCT cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg09904177 chr6:26538194 HMGN4 0.67 6.26 0.49 5.61e-9 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.825 rs10051878 chr5:93064164 T/G cg25358565 chr5:93447407 FAM172A 0.9 7.65 0.57 4.86e-12 Diabetic retinopathy; TGCT cis rs6977660 0.607 rs10243965 chr7:19797893 G/A cg05791153 chr7:19748676 TWISTNB 0.96 5.53 0.44 1.83e-7 Thyroid stimulating hormone; TGCT cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg13393036 chr8:95962371 TP53INP1 -0.61 -8.39 -0.6 9.13e-14 Type 2 diabetes; TGCT trans rs1814175 0.717 rs11040450 chr11:49650638 G/A cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs6964587 1.000 rs756647 chr7:91586389 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs12478296 1.000 rs56136197 chr2:243043877 T/C cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs10032931 0.962 rs1385671 chr4:96455967 C/T cg17031751 chr4:96469067 UNC5C -0.38 -4.92 -0.4 2.73e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs9814567 0.762 rs13070654 chr3:134219348 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.83 6.53 0.51 1.51e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10089 1.000 rs11957052 chr5:127524055 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.4 0.55 1.83e-11 Ileal carcinoids; TGCT cis rs2637266 1.000 rs7897015 chr10:78366566 G/C cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs9916302 0.904 rs7216086 chr17:37709422 G/A cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.68 -7.03 -0.53 1.19e-10 Prostate cancer; TGCT cis rs72781680 1.000 rs75046532 chr2:24167267 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs2050392 0.590 rs694346 chr10:30711929 C/T cg12408189 chr10:30722286 MAP3K8 -0.45 -4.49 -0.37 1.6e-5 Inflammatory bowel disease; TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs736408 0.570 rs11130327 chr3:52793239 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.79 -0.4 4.68e-6 Bipolar disorder; TGCT cis rs17253792 0.822 rs74940664 chr14:56135065 A/G cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs6088580 0.561 rs3761147 chr20:32996689 G/T cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs2811893 0.967 rs232776 chr1:59124803 C/T cg26196860 chr1:59745563 NA 0.25 4.68 0.39 7.49e-6 Diabetic retinopathy; TGCT cis rs6558530 0.579 rs6558528 chr8:1703063 C/T cg09410841 chr8:1729607 CLN8 0.7 6.09 0.48 1.28e-8 Systolic blood pressure; TGCT cis rs881375 0.967 rs7039505 chr9:123705945 A/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.72 0.39 6.28e-6 Rheumatoid arthritis; TGCT cis rs9611519 0.894 rs4821990 chr22:41438710 A/C cg13695892 chr22:41940480 POLR3H -0.55 -4.97 -0.41 2.15e-6 Neuroticism; TGCT cis rs1691799 0.867 rs1168339 chr12:66759236 T/G cg16791601 chr12:66731901 HELB -0.29 -6.18 -0.49 8.39e-9 White blood cell count (basophil); TGCT cis rs7267979 0.966 rs6083817 chr20:25343998 G/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg18252515 chr7:66147081 NA -1.32 -8.25 -0.6 1.93e-13 Diabetic kidney disease; TGCT cis rs4272321 1 rs4272321 chr7:157951835 A/G cg10473311 chr7:158046358 PTPRN2 0.28 4.65 0.39 8.48e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2439831 0.717 rs2470132 chr15:43835481 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.97 7.38 0.55 2.03e-11 Lung cancer in ever smokers; TGCT cis rs2997447 0.655 rs2275950 chr1:26385003 T/C cg19759804 chr1:25889155 LDLRAP1 0.33 4.56 0.38 1.23e-5 QRS complex (12-leadsum); TGCT cis rs3796352 0.571 rs71301816 chr3:53142071 G/A cg27565382 chr3:53032988 SFMBT1 0.42 4.76 0.39 5.31e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs36051895 0.626 rs10283563 chr9:5075603 C/T cg02405213 chr9:5042618 JAK2 -0.86 -12.6 -0.75 5.97e-24 Pediatric autoimmune diseases; TGCT cis rs3858526 0.628 rs1840177 chr11:5944627 T/G cg25319279 chr11:5960081 NA 0.38 4.5 0.37 1.54e-5 DNA methylation (variation); TGCT cis rs765787 0.530 rs4442750 chr15:45535328 G/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs28595532 0.920 rs114667001 chr4:119786974 T/C cg14228332 chr4:119757509 SEC24D 1.3 6.62 0.51 9.62e-10 Cannabis dependence symptom count; TGCT cis rs4925325 1.000 rs4925325 chr20:60514224 G/A cg06108461 chr20:60628389 TAF4 0.39 4.73 0.39 5.98e-6 Obesity-related traits; TGCT cis rs473651 0.935 rs578510 chr2:239343140 C/T cg08773314 chr2:239334832 ASB1 0.45 7.5 0.56 1.07e-11 Multiple system atrophy; TGCT cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg20637647 chr7:64974828 NA 0.88 5.34 0.43 4.19e-7 Diabetic kidney disease; TGCT cis rs6684514 0.922 rs12022657 chr1:156314147 A/G cg16558208 chr1:156270281 VHLL 0.48 9.48 0.65 2.27e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9527 0.614 rs4919691 chr10:104624475 A/C cg15744005 chr10:104629667 AS3MT -0.49 -6.24 -0.49 6.21e-9 Arsenic metabolism; TGCT cis rs1538970 1.000 rs4660852 chr1:45848931 A/C cg05343316 chr1:45956843 TESK2 -0.64 -5.06 -0.41 1.47e-6 Platelet count; TGCT cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs1008375 1.000 rs28552744 chr4:17620165 A/G cg16339924 chr4:17578868 LAP3 0.63 5.13 0.42 1.07e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs9921338 0.961 rs66555362 chr16:11388833 G/T cg00044050 chr16:11439710 C16orf75 -1.0 -7.37 -0.55 2.06e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9393777 0.513 rs9379895 chr6:26592707 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.49 -4.61 -0.38 9.77e-6 Intelligence (multi-trait analysis); TGCT cis rs6495122 0.532 rs2472304 chr15:75044238 G/A cg10253484 chr15:75165896 SCAMP2 -0.69 -6.0 -0.47 2.05e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs7246657 0.722 rs10406379 chr19:38036725 G/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs11621121 0.521 rs2127868 chr14:65794327 G/A cg04536575 chr14:65016802 C14orf50 -0.64 -4.57 -0.38 1.17e-5 N-glycan levels; TGCT cis rs56235845 0.694 rs6875461 chr5:176754665 C/T cg16006841 chr5:176797999 RGS14 -0.49 -7.2 -0.54 5.08e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs1348850 0.750 rs55792594 chr2:178496468 C/T cg22681709 chr2:178499509 PDE11A -0.47 -5.62 -0.45 1.18e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1576263 0.565 rs9392214 chr6:8374696 T/G cg01815076 chr6:8435968 SLC35B3 -0.46 -4.49 -0.37 1.63e-5 Photic sneeze reflex; TGCT cis rs6840360 0.615 rs1877188 chr4:152607931 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.15 -0.48 9.82e-9 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.605 rs886952 chr16:89836781 G/A cg03388025 chr16:89894329 SPIRE2 0.48 8.44 0.6 6.98e-14 Vitiligo; TGCT cis rs826838 0.967 rs980572 chr12:39127673 A/C cg26384229 chr12:38710491 ALG10B 0.89 8.38 0.6 9.61e-14 Heart rate; TGCT cis rs453301 0.522 rs1964356 chr8:8853270 G/T cg06636001 chr8:8085503 FLJ10661 0.71 6.32 0.49 4.32e-9 Joint mobility (Beighton score); TGCT cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg17971929 chr21:40555470 PSMG1 0.98 9.47 0.65 2.42e-16 Cognitive function; TGCT cis rs2204008 0.806 rs35534445 chr12:38279093 C/T cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs10858047 0.883 rs3789624 chr1:115116434 A/G cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs1008375 0.966 rs3775924 chr4:17585984 T/C cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7119 0.651 rs34607443 chr15:77847892 C/T cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs1552244 0.882 rs56224841 chr3:10044014 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs7312933 0.703 rs12370778 chr12:42599696 T/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9486719 0.947 rs72932805 chr6:96902933 T/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.77 -0.62 1.18e-14 Migraine;Coronary artery disease; TGCT cis rs3996993 0.752 rs2749026 chr6:52630635 A/G cg20803780 chr6:52668592 GSTA1 -0.36 -4.59 -0.38 1.06e-5 Hemoglobin concentration; TGCT cis rs360798 0.512 rs2710642 chr2:63149557 G/A cg17519650 chr2:63277830 OTX1 0.57 4.87 0.4 3.3e-6 Coronary artery disease; TGCT cis rs57590327 0.503 rs11711024 chr3:81910207 T/C cg07356753 chr3:81810745 GBE1 -0.67 -6.19 -0.49 7.97e-9 Extraversion; TGCT cis rs12579753 1.000 rs10862371 chr12:82249298 C/T cg07988820 chr12:82153109 PPFIA2 -0.6 -6.61 -0.51 1.02e-9 Resting heart rate; TGCT cis rs3845702 0.736 rs259810 chr2:180787821 T/C cg01881094 chr2:180872142 CWC22 -1.02 -6.47 -0.5 2.09e-9 Schizophrenia; TGCT cis rs3617 0.539 rs9880619 chr3:52953055 G/A cg11645453 chr3:52864694 ITIH4 -0.27 -5.37 -0.43 3.76e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Vitiligo; TGCT cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg11890956 chr21:40555474 PSMG1 -1.09 -12.05 -0.73 1.28e-22 Cognitive function; TGCT cis rs548987 0.507 rs1408268 chr6:25826986 T/A cg12310025 chr6:25882481 NA -0.57 -4.61 -0.38 9.67e-6 Homocysteine levels; TGCT cis rs35146811 0.700 rs2950520 chr7:99827148 T/C cg22906224 chr7:99728672 NA -0.49 -4.49 -0.37 1.62e-5 Coronary artery disease; TGCT cis rs72627509 0.904 rs7687767 chr4:57824932 C/T cg26694713 chr4:57773883 REST -0.75 -6.8 -0.52 3.94e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs13217239 0.646 rs4583981 chr6:26992023 G/T cg02458000 chr6:26745757 NA 0.51 4.72 0.39 6.22e-6 Schizophrenia; TGCT cis rs478304 0.651 rs10896037 chr11:65503424 A/G cg27068330 chr11:65405492 SIPA1 -0.94 -9.4 -0.65 3.49e-16 Acne (severe); TGCT cis rs2455799 0.613 rs13080234 chr3:15852492 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.19e-6 Mean platelet volume; TGCT cis rs13323323 0.691 rs9814256 chr3:44668037 A/T cg04389838 chr3:44770851 ZNF501 -0.44 -4.68 -0.39 7.43e-6 IgG glycosylation; TGCT cis rs514406 0.830 rs533935 chr1:53308807 T/C cg24675658 chr1:53192096 ZYG11B -0.71 -7.73 -0.57 3.2e-12 Monocyte count; TGCT cis rs11190604 1.000 rs11190555 chr10:102209160 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4455778 0.633 rs2098127 chr7:49007109 A/G cg26309511 chr7:48887640 NA -0.5 -5.95 -0.47 2.57e-8 Lung cancer in never smokers; TGCT trans rs7618501 1.000 rs34451146 chr3:49813013 C/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.696 rs12140121 chr1:76455001 A/G cg10523679 chr1:76189770 ACADM 0.83 6.78 0.52 4.35e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7677751 0.767 rs11133315 chr4:55082158 G/A cg17187183 chr4:55093834 PDGFRA 0.54 7.02 0.53 1.26e-10 Corneal astigmatism; TGCT cis rs2115630 0.691 rs61322921 chr15:85163638 T/C cg11189052 chr15:85197271 WDR73 -0.74 -7.35 -0.55 2.34e-11 P wave terminal force; TGCT cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg01802117 chr1:53393560 SCP2 0.48 5.82 0.46 4.82e-8 Monocyte count; TGCT cis rs9467773 0.935 rs1056668 chr6:26510605 C/T cg05738196 chr6:26577821 NA 0.85 11.07 0.71 3.1e-20 Intelligence (multi-trait analysis); TGCT cis rs4372836 0.543 rs3768665 chr2:29005602 G/A cg09522027 chr2:28974177 PPP1CB -0.72 -6.88 -0.53 2.59e-10 Body mass index; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg04321618 chr7:27170880 HOXA4 -0.56 -5.49 -0.44 2.19e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7826238 0.509 rs2948288 chr8:8115304 A/G cg06636001 chr8:8085503 FLJ10661 0.84 8.38 0.6 9.46e-14 Systolic blood pressure; TGCT cis rs6671200 1.000 rs6671200 chr1:95697529 A/C cg03123541 chr1:95699097 RWDD3 -0.91 -6.4 -0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs2288278 0.601 rs72829818 chr17:46589885 C/A cg25032089 chr17:46643351 HOXB3 -0.41 -4.8 -0.4 4.55e-6 Hand grip strength; TGCT cis rs4664308 1.000 rs4665147 chr2:160917062 A/G cg03641300 chr2:160917029 PLA2R1 -0.26 -6.44 -0.5 2.33e-9 Idiopathic membranous nephropathy; TGCT cis rs758129 0.501 rs12899409 chr15:89868256 A/C cg24365117 chr15:89879190 POLG 0.34 4.84 0.4 3.8e-6 Schizophrenia; TGCT cis rs539096 0.872 rs2842186 chr1:44035093 A/G cg12908607 chr1:44402522 ARTN 0.51 5.32 0.43 4.65e-7 Intelligence (multi-trait analysis); TGCT trans rs1864729 1.000 rs2635162 chr8:98283629 C/T cg08679828 chr8:102218111 ZNF706 -1.1 -7.71 -0.57 3.56e-12 Estradiol plasma levels (breast cancer); TGCT cis rs6964587 0.967 rs6465341 chr7:91596121 G/C cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6582630 0.537 rs3942440 chr12:38459672 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT trans rs877282 0.945 rs11599043 chr10:777972 C/T cg22713356 chr15:30763199 NA 1.14 10.34 0.68 1.93e-18 Uric acid levels; TGCT cis rs875971 0.929 rs34406470 chr7:65929956 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs9916302 0.904 rs801426 chr17:37441109 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.7 -0.39 6.89e-6 Glomerular filtration rate (creatinine); TGCT cis rs17122693 0.551 rs1812181 chr14:51052669 C/T cg04730355 chr14:51134070 SAV1 1.19 11.83 0.73 4.33e-22 Cognitive performance; TGCT cis rs208520 0.754 rs851593 chr6:66875783 C/T cg07460842 chr6:66804631 NA 0.91 9.43 0.65 2.99e-16 Exhaled nitric oxide output; TGCT cis rs7772486 0.875 rs854146 chr6:146341033 A/G cg05347473 chr6:146136440 FBXO30 0.53 5.02 0.41 1.73e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3008870 1.000 rs2009319 chr1:67481070 G/T cg11518657 chr1:67396239 MIER1 0.54 4.65 0.39 8.44e-6 Lymphocyte percentage of white cells; TGCT cis rs35146811 0.806 rs1534310 chr7:99699169 A/T cg22906224 chr7:99728672 NA 0.5 4.46 0.37 1.82e-5 Coronary artery disease; TGCT cis rs7954584 0.531 rs10840631 chr12:122373729 C/T cg21171335 chr12:122356390 WDR66 0.7 7.03 0.53 1.24e-10 Mean corpuscular volume; TGCT trans rs1005277 0.579 rs1780146 chr10:38517874 C/A cg27523141 chr10:43048294 ZNF37B 0.71 8.26 0.6 1.84e-13 Extrinsic epigenetic age acceleration; TGCT cis rs67460515 0.892 rs16832082 chr3:161043571 A/G cg03342759 chr3:160939853 NMD3 -0.49 -5.29 -0.43 5.28e-7 Parkinson's disease; TGCT trans rs9388451 0.626 rs3799712 chr6:126075103 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.87 -9.72 -0.66 6.01e-17 Brugada syndrome; TGCT trans rs629535 1.000 rs629535 chr8:70007938 C/T cg21567404 chr3:27674614 NA -0.55 -8.31 -0.6 1.43e-13 Dupuytren's disease; TGCT cis rs35306767 0.714 rs66797613 chr10:1090469 C/T cg18964960 chr10:1102726 WDR37 0.68 4.77 0.39 5.02e-6 Eosinophil percentage of granulocytes; TGCT cis rs7917772 0.636 rs7069489 chr10:104525371 A/G cg05855489 chr10:104503620 C10orf26 -0.65 -5.38 -0.43 3.64e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7267979 1.000 rs2027004 chr20:25350618 C/T cg03522245 chr20:25566470 NINL -0.61 -6.63 -0.51 9.11e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5417 0.662 rs8067500 chr17:7172631 A/G cg25256661 chr17:7137939 DVL2 0.71 7.26 0.55 3.73e-11 Diastolic blood pressure; TGCT cis rs7131987 0.903 rs918873 chr12:29390501 G/T cg09582351 chr12:29534625 ERGIC2 -0.23 -4.52 -0.38 1.43e-5 QT interval; TGCT cis rs7091068 0.507 rs913046 chr10:95408484 A/C cg20715218 chr10:95462985 C10orf4 0.48 6.0 0.47 2.01e-8 Urinary tract infection frequency; TGCT cis rs28493229 0.881 rs10404911 chr19:41174903 A/T cg11601297 chr19:41224147 ITPKC;ADCK4 0.59 5.61 0.45 1.27e-7 Kawasaki disease; TGCT cis rs595982 0.702 rs623520 chr19:49369943 A/G cg21252483 chr19:49399788 TULP2 -0.26 -4.57 -0.38 1.18e-5 Red cell distribution width; TGCT cis rs57920188 0.535 rs10915658 chr1:4092921 T/C cg20703997 chr1:4087676 NA 0.48 5.74 0.46 6.87e-8 Interleukin-17 levels; TGCT cis rs12220898 0.749 rs2377978 chr10:50476193 C/A cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.85e-5 Inflammatory biomarkers; TGCT cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg02458000 chr6:26745757 NA 0.63 6.04 0.48 1.68e-8 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg07424592 chr7:64974309 NA -1.27 -7.28 -0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs28595532 0.920 rs116612909 chr4:119749823 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10174077 0.687 rs4664491 chr2:152479986 C/T cg06191203 chr2:152266755 RIF1 -0.62 -5.8 -0.46 5.06e-8 Squamous cell lung carcinoma; TGCT cis rs9581857 0.579 rs76578450 chr13:27982656 C/A cg22138327 chr13:27999177 GTF3A 0.71 5.23 0.43 6.91e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6570726 0.935 rs436212 chr6:145849400 G/A cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs208520 0.690 rs12213928 chr6:66762978 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.29 0.71 9.4e-21 Exhaled nitric oxide output; TGCT cis rs12682352 0.715 rs332039 chr8:8723651 C/G cg17143192 chr8:8559678 CLDN23 0.45 4.64 0.38 8.65e-6 Neuroticism; TGCT cis rs950169 0.922 rs12912934 chr15:85114447 C/T cg17173187 chr15:85201210 NMB 0.47 4.93 0.4 2.62e-6 Schizophrenia; TGCT cis rs370915 0.542 rs1895844 chr4:187833759 C/T cg19519643 chr4:187840862 NA -0.22 -4.49 -0.37 1.6e-5 Gout; TGCT cis rs7786808 0.564 rs10267128 chr7:158198490 G/A cg01191920 chr7:158217561 PTPRN2 0.37 5.4 0.44 3.23e-7 Obesity-related traits; TGCT cis rs933688 1.000 rs11959525 chr5:90703840 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.91 7.87 0.58 1.49e-12 Smoking behavior; TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg04321618 chr7:27170880 HOXA4 -0.52 -5.33 -0.43 4.47e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2235642 0.691 rs2281235 chr16:1603535 T/C cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.64 -0.45 1.08e-7 Coronary artery disease; TGCT cis rs116095464 0.558 rs61492827 chr5:225774 A/G cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs11874712 0.931 rs8095031 chr18:43666861 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg03303774 chr4:1407052 NA -0.32 -4.88 -0.4 3.21e-6 Obesity-related traits; TGCT cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg06634786 chr22:41940651 POLR3H 0.69 6.54 0.51 1.45e-9 Vitiligo; TGCT cis rs77140172 0.655 rs79387006 chr4:89672775 A/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.15 5.23 0.43 6.86e-7 Post bronchodilator FEV1; TGCT cis rs6882076 1.000 rs13167071 chr5:156373637 G/C cg12943317 chr5:156479607 HAVCR1 -0.3 -5.24 -0.43 6.73e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs4566357 0.787 rs6748048 chr2:227822440 T/C cg11843606 chr2:227700838 RHBDD1 -0.61 -5.26 -0.43 6.15e-7 Coronary artery disease; TGCT cis rs1552244 0.572 rs67439440 chr3:10169503 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs12497850 0.897 rs9884022 chr3:48956862 G/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.19e-7 Parkinson's disease; TGCT cis rs28595532 0.920 rs55758547 chr4:119769475 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs3806843 0.576 rs265316 chr5:140290843 T/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.44 -5.32 -0.43 4.6e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs2727020 0.619 rs11040300 chr11:49269984 C/A cg15704280 chr7:45808275 SEPT13 0.68 7.13 0.54 7.39e-11 Coronary artery disease; TGCT trans rs17685 0.753 rs1637044 chr7:75703744 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs4242434 0.819 rs7843128 chr8:22473465 T/C cg03733263 chr8:22462867 KIAA1967 1.08 17.06 0.84 2.57e-34 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs1215050 0.791 rs2123099 chr4:98803456 A/G cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg20818283 chr2:191399100 TMEM194B 0.49 4.44 0.37 1.94e-5 Pulse pressure; TGCT cis rs12541335 0.603 rs9792127 chr8:22180334 G/A cg02788857 chr8:22132959 PIWIL2 0.27 5.06 0.41 1.45e-6 Hypertriglyceridemia; TGCT cis rs950027 0.620 rs1145093 chr15:45649813 C/A cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs4665809 1.000 rs4665819 chr2:26309073 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs2013441 1.000 rs2120282 chr17:20209474 C/T cg23224458 chr17:20280056 CCDC144C -0.41 -4.88 -0.4 3.25e-6 Obesity-related traits; TGCT cis rs60843830 1.000 rs36216559 chr2:262335 A/G cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.93 0.53 2.07e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs17122693 1.000 rs72679549 chr14:51050822 G/A cg04730355 chr14:51134070 SAV1 1.25 8.82 0.62 8.76e-15 Cognitive performance; TGCT cis rs3734905 1.000 rs77336201 chr6:169942337 T/G cg20469989 chr6:170102314 C6orf120;WDR27 -0.88 -4.67 -0.39 7.59e-6 HIV-1 control; TGCT cis rs11587400 0.532 rs2268700 chr1:115228879 T/G cg12756093 chr1:115239321 AMPD1 -0.33 -4.87 -0.4 3.31e-6 Autism; TGCT cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9659323 1.000 rs10923714 chr1:119512913 C/T cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.4e-6 Body mass index; TGCT cis rs10089 1.000 rs10478803 chr5:127488855 T/C cg19767477 chr5:127420684 SLC12A2 -0.43 -4.52 -0.38 1.43e-5 Ileal carcinoids; TGCT cis rs1215050 0.791 rs165237 chr4:98712029 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1218582 0.774 rs4845679 chr1:154861187 G/T cg16680214 chr1:154839983 KCNN3 -0.42 -9.22 -0.64 9.71e-16 Prostate cancer; TGCT cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg05368731 chr17:41323189 NBR1 1.18 13.93 0.78 3.99e-27 Menopause (age at onset); TGCT cis rs4319547 0.956 rs10847179 chr12:123040985 T/C cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.49 -0.44 2.22e-7 Body mass index; TGCT cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg26531700 chr6:26746687 NA 0.51 4.61 0.38 9.86e-6 Intelligence (multi-trait analysis); TGCT cis rs12579753 0.719 rs4418884 chr12:82277006 C/T cg07988820 chr12:82153109 PPFIA2 -0.42 -4.44 -0.37 1.93e-5 Resting heart rate; TGCT cis rs4746818 0.892 rs12437 chr10:70864065 T/C cg11621586 chr10:70884670 VPS26A 1.15 9.19 0.64 1.14e-15 Left atrial antero-posterior diameter; TGCT cis rs10751667 0.643 rs10794352 chr11:946294 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.29 -0.6 1.6e-13 Alzheimer's disease (late onset); TGCT cis rs59948050 1 rs59948050 chr1:15915157 T/G cg05660106 chr1:15850417 CASP9 0.88 6.35 0.5 3.65e-9 Morning vs. evening chronotype; TGCT cis rs9522267 0.737 rs9522285 chr13:112230701 C/T cg10483660 chr13:112241077 NA -0.28 -4.6 -0.38 1.01e-5 Hepatitis; TGCT cis rs10791097 0.667 rs2155358 chr11:130740357 T/C cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9952991 0.941 rs7237497 chr18:12777325 T/C cg23544223 chr18:12777786 NA 0.64 6.12 0.48 1.15e-8 Inflammatory skin disease; TGCT cis rs71435601 0.628 rs532300 chr2:21381608 C/A cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs611744 0.967 rs702802 chr8:109218238 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7726839 0.540 rs3749618 chr5:602650 A/G cg20362242 chr5:692897 TPPP 0.5 4.49 0.37 1.64e-5 Obesity-related traits; TGCT cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12286929 0.651 rs12274772 chr11:115098768 C/T cg04017736 chr11:115827165 NA -0.2 -4.95 -0.41 2.42e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs986417 0.748 rs1956552 chr14:60942685 A/G cg27398547 chr14:60952738 C14orf39 1.49 10.81 0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs2230307 0.536 rs506044 chr1:100611931 A/G cg24955406 chr1:100503596 HIAT1 -0.73 -4.96 -0.41 2.27e-6 Carotid intima media thickness; TGCT cis rs9916302 0.706 rs28482878 chr17:37497100 A/G cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs6089829 0.962 rs1060490 chr20:61665871 A/G cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs9914988 0.943 rs2046759 chr17:27138817 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9790314 0.846 rs4856738 chr3:160986637 C/G cg03342759 chr3:160939853 NMD3 -0.48 -5.23 -0.43 6.93e-7 Morning vs. evening chronotype; TGCT cis rs67478160 0.619 rs11160759 chr14:104231542 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.57 -0.51 1.25e-9 Schizophrenia; TGCT cis rs5167 0.566 rs934427 chr19:45478816 T/G cg13119609 chr19:45449297 APOC2 0.23 4.62 0.38 9.31e-6 Blood protein levels; TGCT trans rs4824093 0.610 rs73441787 chr22:50269646 A/G cg09872104 chr7:134855509 C7orf49 -0.94 -7.68 -0.57 4.2e-12 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs35883536 0.626 rs10783140 chr1:101042083 A/G cg10298815 chr1:101004474 GPR88 -0.25 -4.73 -0.39 6.03e-6 Monocyte count; TGCT cis rs9534288 0.797 rs7328081 chr13:46611695 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.75 -0.57 2.87e-12 Blood protein levels; TGCT cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg08219700 chr8:58056026 NA 0.38 4.71 0.39 6.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs9457247 1.000 rs364283 chr6:167383750 C/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs9926296 0.568 rs1230 chr16:89804855 A/G cg26513180 chr16:89883248 FANCA -1.08 -15.47 -0.81 1e-30 Vitiligo; TGCT cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg05665937 chr4:1216051 CTBP1 0.26 4.89 0.4 3.02e-6 Obesity-related traits; TGCT cis rs651907 0.557 rs7651406 chr3:101393296 C/T cg12386194 chr3:101231763 SENP7 0.51 5.04 0.41 1.61e-6 Colorectal cancer; TGCT cis rs1538970 0.851 rs61788285 chr1:45919234 A/C cg05343316 chr1:45956843 TESK2 0.86 6.87 0.53 2.7e-10 Platelet count; TGCT cis rs9611565 0.592 rs9611612 chr22:41961189 T/C cg13695892 chr22:41940480 POLR3H -0.87 -8.29 -0.6 1.6e-13 Vitiligo; TGCT cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg00343986 chr7:65444356 GUSB 0.26 6.07 0.48 1.42e-8 Aortic root size; TGCT cis rs4822044 0.561 rs132781 chr22:42046122 T/G cg03806693 chr22:41940476 POLR3H 1.1 11.41 0.72 4.6e-21 Cannabis dependence symptom count; TGCT cis rs2204008 0.557 rs11520191 chr12:38197057 T/A cg13010199 chr12:38710504 ALG10B 0.62 4.87 0.4 3.35e-6 Bladder cancer; TGCT cis rs7474896 0.515 rs624359 chr10:38299132 T/C cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs587847 0.558 rs681830 chr15:37676786 T/A cg16890051 chr15:37175029 LOC145845 -0.37 -4.44 -0.37 1.95e-5 Intraocular pressure; TGCT trans rs1814175 0.817 rs4881623 chr11:49804991 C/T cg15704280 chr7:45808275 SEPT13 -0.7 -8.08 -0.59 4.89e-13 Height; TGCT cis rs35146811 0.735 rs1727138 chr7:99815247 A/G cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs9868809 0.772 rs2302295 chr3:48690110 T/C cg00383909 chr3:49044727 WDR6 0.99 5.68 0.45 8.95e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs1538970 0.924 rs1007858 chr1:45912005 C/T cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs60871478 0.947 rs62432239 chr7:794576 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.44 4.44 0.37 1.96e-5 Cerebrospinal P-tau181p levels; TGCT cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.4 0.55 1.78e-11 Schizophrenia; TGCT cis rs950169 0.887 rs62029593 chr15:84955180 A/G cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs9926296 0.585 rs4785595 chr16:89835521 C/T cg21285383 chr16:89894308 SPIRE2 -0.45 -7.18 -0.54 5.5e-11 Vitiligo; TGCT cis rs2439831 0.850 rs8032649 chr15:44134922 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.68 -4.47 -0.37 1.74e-5 Lung cancer in ever smokers; TGCT cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs2932538 0.961 rs6537747 chr1:113179597 C/T cg22162597 chr1:113214053 CAPZA1 -0.26 -5.82 -0.46 4.83e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs4664308 0.967 rs17241792 chr2:160915205 C/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.38 -0.5 3.26e-9 Idiopathic membranous nephropathy; TGCT cis rs3749237 0.595 rs1568661 chr3:49520958 A/G cg03060546 chr3:49711283 APEH 0.75 8.45 0.6 6.48e-14 Resting heart rate; TGCT cis rs10832169 0.967 rs12797530 chr11:14063439 C/T cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs1555895 0.611 rs2892159 chr10:855061 G/A cg02193355 chr10:851439 NA 0.21 4.78 0.39 4.82e-6 Survival in rectal cancer; TGCT cis rs1372520 0.577 rs2737021 chr4:90739992 T/A cg20003494 chr4:90757398 SNCA -0.66 -5.2 -0.42 7.87e-7 Neuroticism; TGCT cis rs9611519 0.780 rs5751071 chr22:41656332 G/A cg03806693 chr22:41940476 POLR3H -0.75 -7.3 -0.55 3e-11 Neuroticism; TGCT cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT trans rs7819412 0.654 rs4840550 chr8:11029029 T/G cg06636001 chr8:8085503 FLJ10661 -0.81 -7.4 -0.55 1.82e-11 Triglycerides; TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg02353165 chr6:42928485 GNMT 0.99 10.14 0.67 5.89e-18 Plasma homocysteine levels (post-methionine load test); TGCT cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg11890956 chr21:40555474 PSMG1 -0.72 -6.47 -0.5 2.07e-9 Cognitive function; TGCT cis rs3849570 1.000 rs9842330 chr3:81814688 G/A cg07356753 chr3:81810745 GBE1 -0.82 -7.62 -0.56 5.6e-12 Waist circumference;Body mass index; TGCT cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg19318889 chr4:1322082 MAEA 0.28 6.7 0.52 6.39e-10 Longevity; TGCT trans rs2727020 0.658 rs7120136 chr11:49384358 A/C cg03929089 chr4:120376271 NA -0.75 -8.63 -0.61 2.53e-14 Coronary artery disease; TGCT cis rs2153535 0.562 rs6901765 chr6:8455436 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4285028 0.948 rs34158925 chr3:121678465 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs3806843 0.576 rs246074 chr5:140307969 C/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.43 -5.33 -0.43 4.42e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs2760061 0.819 rs964941 chr1:228193857 G/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.24 -0.55 4.17e-11 Diastolic blood pressure; TGCT cis rs3806843 0.521 rs192231 chr5:140248539 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.42 5.06 0.41 1.48e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6893807 0.778 rs1501672 chr5:87963761 A/G cg24804195 chr5:87968844 LOC645323 0.81 4.9 0.4 2.87e-6 Body mass index; TGCT cis rs9905704 0.647 rs3809723 chr17:57061978 T/G cg12560992 chr17:57184187 TRIM37 0.58 5.17 0.42 9.08e-7 Testicular germ cell tumor; TGCT cis rs35306767 0.855 rs2050944 chr10:918910 T/C cg20503657 chr10:835505 NA 0.74 10.27 0.68 2.77e-18 Eosinophil percentage of granulocytes; TGCT cis rs9807989 0.507 rs1420097 chr2:103009354 C/G cg03938978 chr2:103052716 IL18RAP -0.26 -5.19 -0.42 8.29e-7 Asthma; TGCT cis rs6725041 0.819 rs1521645 chr2:213091216 A/G cg16329650 chr2:213403929 ERBB4 -0.53 -4.58 -0.38 1.12e-5 QT interval (ambient particulate matter interaction); TGCT cis rs4689592 0.503 rs4689064 chr4:7055603 A/G cg25660036 chr4:7070649 GRPEL1 0.56 4.46 0.37 1.79e-5 Monocyte percentage of white cells; TGCT cis rs7312933 0.703 rs12370778 chr12:42599696 T/A cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9311474 0.502 rs4687624 chr3:52563572 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.64 -0.61 2.37e-14 Electroencephalogram traits; TGCT cis rs713587 0.713 rs62143001 chr2:25288675 G/A cg01884057 chr2:25150051 NA -0.39 -8.01 -0.58 7.24e-13 Body mass index in non-asthmatics; TGCT cis rs76419734 0.558 rs10516520 chr4:106534110 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.81 4.68 0.39 7.31e-6 Post bronchodilator FEV1; TGCT cis rs7572733 0.534 rs1983359 chr2:198805098 C/T cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs2932538 0.922 rs12143068 chr1:113138110 A/G cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9560113 0.573 rs9560134 chr13:112244011 C/T cg10483660 chr13:112241077 NA 0.36 5.51 0.44 1.97e-7 Menarche (age at onset); TGCT cis rs6089829 0.851 rs10854168 chr20:61669550 A/G cg08045932 chr20:61659980 NA 0.5 8.69 0.62 1.75e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs72717009 0.756 rs10494359 chr1:161463876 G/C cg23840854 chr1:161414152 NA -1.02 -6.37 -0.5 3.42e-9 Rheumatoid arthritis; TGCT cis rs1903068 0.962 rs17773813 chr4:56008969 G/A cg01777861 chr4:56023843 NA 0.55 6.49 0.5 1.86e-9 Endometriosis; TGCT cis rs7584330 0.518 rs74003108 chr2:238448000 T/C cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs1857353 1.000 rs12408226 chr1:75889444 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs903263 0.965 rs11163907 chr1:84597396 T/C cg09664975 chr1:84543551 PRKACB 0.5 4.67 0.39 7.62e-6 Breast cancer (male); TGCT trans rs7726839 0.540 rs72703078 chr5:594987 A/C cg11887960 chr12:57824829 NA 1.2 9.65 0.65 8.99e-17 Obesity-related traits; TGCT cis rs2836974 0.897 rs13049280 chr21:40594656 C/G cg06238570 chr21:40685208 BRWD1 0.58 5.16 0.42 9.63e-7 Cognitive function; TGCT cis rs3820928 0.967 rs4675113 chr2:227766339 G/A cg11843606 chr2:227700838 RHBDD1 -0.51 -4.49 -0.37 1.6e-5 Pulmonary function; TGCT cis rs9467773 1.000 rs9467782 chr6:26542773 G/A cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs2692947 0.644 rs772175 chr2:96944553 G/A cg22654517 chr2:96458247 NA 0.22 4.85 0.4 3.67e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs17376456 0.877 rs10061080 chr5:93420559 A/G cg25358565 chr5:93447407 FAM172A 0.94 8.34 0.6 1.2e-13 Diabetic retinopathy; TGCT cis rs2066819 0.901 rs1274490 chr12:56649601 A/G cg26714650 chr12:56694279 CS 1.51 8.32 0.6 1.33e-13 Psoriasis vulgaris; TGCT cis rs4713118 0.621 rs9295756 chr6:28033396 G/T cg12963246 chr6:28129442 ZNF389 0.45 4.48 0.37 1.64e-5 Parkinson's disease; TGCT cis rs72615157 0.613 rs56089143 chr7:99819844 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.95 0.41 2.34e-6 Lung function (FEV1/FVC); TGCT cis rs10779751 0.690 rs743577 chr1:11119135 G/A cg08854313 chr1:11322531 MTOR 0.84 8.17 0.59 2.98e-13 Body mass index; TGCT cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg08280861 chr8:58055591 NA 0.36 4.98 0.41 2.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg02493798 chr17:6899577 ALOX12 -0.43 -5.06 -0.41 1.47e-6 Tonsillectomy; TGCT cis rs116095464 0.558 rs10043002 chr5:226753 G/A cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.49 0.37 1.62e-5 Breast cancer; TGCT cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg03060546 chr3:49711283 APEH 0.53 5.14 0.42 1.05e-6 Menarche (age at onset); TGCT cis rs8016982 0.633 rs4363794 chr14:81674327 C/A cg01989461 chr14:81687754 GTF2A1 0.75 7.13 0.54 7.17e-11 Schizophrenia; TGCT cis rs7914558 0.966 rs2065977 chr10:104729415 C/T cg15744005 chr10:104629667 AS3MT -0.4 -4.97 -0.41 2.21e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3796352 1.000 rs35720014 chr3:52982110 A/C cg07884673 chr3:53033167 SFMBT1 0.63 5.74 0.46 6.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg20637647 chr7:64974828 NA 0.88 5.12 0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs7552404 0.731 rs5745458 chr1:76345429 G/A cg22875332 chr1:76189707 ACADM -0.68 -7.11 -0.54 7.96e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7017914 0.905 rs1908036 chr8:71922324 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs7655841 0.704 rs3113490 chr4:129965671 T/C cg26347359 chr4:129759716 PHF17 -0.43 -4.98 -0.41 2.07e-6 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs1218582 0.772 rs906593 chr1:154885255 G/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg05896524 chr21:47604654 C21orf56 0.42 4.45 0.37 1.91e-5 Testicular germ cell tumor; TGCT cis rs9921222 0.509 rs3743883 chr16:404750 T/C cg10349874 chr16:420996 TMEM8A;MRPL28 -0.34 -6.24 -0.49 6.35e-9 Bone mineral density (spine);Bone mineral density; TGCT cis rs12477438 0.798 rs13393860 chr2:99590397 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs6867032 0.958 rs4975795 chr5:2015390 G/A cg26168224 chr5:2018326 NA 0.43 7.81 0.57 2.03e-12 Gut microbiome composition (winter); TGCT cis rs11792861 0.888 rs11794648 chr9:111829792 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.9 0.4 2.89e-6 Menarche (age at onset); TGCT cis rs12200560 0.505 rs2015196 chr6:97075331 G/C cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs9818758 0.607 rs9850917 chr3:49286983 A/G cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7666738 0.822 rs9992360 chr4:98937123 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6912958 0.781 rs3934838 chr6:88284699 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg20637647 chr7:64974828 NA 0.95 5.3 0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs1799949 0.930 rs1554063 chr17:41287145 T/C cg05368731 chr17:41323189 NBR1 1.07 12.07 0.73 1.17e-22 Menopause (age at onset); TGCT cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs3008870 0.755 rs3736905 chr1:67392614 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.47 0.61 5.86e-14 Lymphocyte percentage of white cells; TGCT cis rs7412746 0.658 rs2230061 chr1:150727539 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.57 0.38 1.15e-5 Melanoma; TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg17178900 chr1:205818956 PM20D1 0.67 9.42 0.65 3.15e-16 Menarche (age at onset); TGCT cis rs9399135 0.967 rs17638970 chr6:135320063 A/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs10779751 1.000 rs4845854 chr1:11261929 T/C cg08854313 chr1:11322531 MTOR 0.93 8.83 0.62 8.25e-15 Body mass index; TGCT cis rs137699 0.652 rs137707 chr22:39751401 T/C cg24399712 chr22:39784796 NA -0.81 -6.51 -0.5 1.66e-9 IgG glycosylation; TGCT cis rs6545883 1.000 rs778763 chr2:61785639 C/G cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs709400 0.663 rs72708893 chr14:103929535 G/A cg26031613 chr14:104095156 KLC1 0.86 9.53 0.65 1.71e-16 Body mass index; TGCT cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg06640241 chr16:89574553 SPG7 0.8 9.08 0.63 2.12e-15 Multiple myeloma (IgH translocation); TGCT cis rs7586879 0.796 rs916486 chr2:25082629 C/A cg01884057 chr2:25150051 NA 0.26 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs926938 0.552 rs360613 chr1:115394864 C/G cg12756093 chr1:115239321 AMPD1 0.4 5.79 0.46 5.56e-8 Autism; TGCT cis rs2469997 0.925 rs2470004 chr8:120358445 C/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs4242434 0.927 rs2291234 chr8:22464390 T/C cg21658235 chr8:22456391 C8orf58 0.43 4.53 0.38 1.37e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2239547 0.618 rs3733047 chr3:52871929 A/G cg11645453 chr3:52864694 ITIH4 -0.32 -5.59 -0.45 1.38e-7 Schizophrenia; TGCT cis rs11748684 1.000 rs59463904 chr5:42559473 T/C cg01169772 chr5:41904236 C5orf51 -0.92 -4.5 -0.37 1.54e-5 Response to taxane treatment (docetaxel); TGCT trans rs2688608 0.592 rs12253482 chr10:75496130 G/A cg13918328 chr10:52500089 ASAH2B 0.68 6.77 0.52 4.51e-10 Inflammatory bowel disease; TGCT cis rs1541995 1.000 rs4984607 chr15:96314174 G/A cg00882281 chr15:96346592 NA 0.29 4.68 0.39 7.26e-6 Photic sneeze reflex; TGCT cis rs7666738 0.830 rs35213297 chr4:98984049 T/C cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs13242816 0.881 rs35210394 chr7:116104911 C/G cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT cis rs4455778 0.580 rs3924858 chr7:49121340 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs4727027 0.840 rs12670633 chr7:148796707 G/A cg23583168 chr7:148888333 NA -0.72 -9.11 -0.63 1.8e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7412746 0.621 rs7518156 chr1:150945794 A/C cg04414720 chr1:150670196 GOLPH3L 0.39 4.6 0.38 1.04e-5 Melanoma; TGCT cis rs751728 0.689 rs3763257 chr6:33773696 T/A cg13859433 chr6:33739653 LEMD2 -0.38 -6.72 -0.52 5.77e-10 Crohn's disease; TGCT cis rs2334880 0.678 rs57821244 chr16:71553791 G/C cg06353428 chr16:71660113 MARVELD3 -1.32 -7.58 -0.56 6.9e-12 Malaria; TGCT cis rs7208859 0.673 rs216418 chr17:28936537 G/A cg04154034 chr17:28927549 LRRC37B2 0.74 4.56 0.38 1.22e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11122272 0.735 rs2486730 chr1:231534987 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.64 -0.51 8.59e-10 Hemoglobin concentration; TGCT cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT cis rs910316 0.737 rs175048 chr14:75479894 A/T cg08847533 chr14:75593920 NEK9 -0.83 -8.92 -0.63 5.18e-15 Height; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.8e-11 Prudent dietary pattern; TGCT cis rs2841233 0.558 rs10145270 chr14:105349891 G/A cg03469805 chr14:105330648 KIAA0284 -0.47 -5.52 -0.44 1.87e-7 IgG glycosylation; TGCT cis rs9549367 0.789 rs9577220 chr13:113908294 T/A cg00898013 chr13:113819073 PROZ -0.43 -5.55 -0.45 1.68e-7 Platelet distribution width; TGCT cis rs2227564 0.620 rs12783161 chr10:75572201 G/C cg19442545 chr10:75533431 FUT11 -0.31 -4.48 -0.37 1.65e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9296661 0.522 rs2182505 chr6:51653864 T/C cg20180370 chr6:50691003 TFAP2D -0.49 -4.7 -0.39 6.71e-6 Weight loss (gastric bypass surgery); TGCT cis rs7412746 0.658 rs8444 chr1:150938571 G/A cg04414720 chr1:150670196 GOLPH3L 0.4 4.62 0.38 9.58e-6 Melanoma; TGCT trans rs62103177 0.759 rs7227794 chr18:77610925 C/T cg05926928 chr17:57297772 GDPD1 1.22 11.62 0.72 1.41e-21 Opioid sensitivity; TGCT cis rs2797160 1.000 rs1739371 chr6:126011291 G/A cg05901451 chr6:126070800 HEY2 0.75 6.33 0.49 4.14e-9 Endometrial cancer; TGCT cis rs6582630 0.555 rs11182202 chr12:38476451 C/G cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs56235845 0.694 rs6876677 chr5:176755342 T/C cg16006841 chr5:176797999 RGS14 0.49 7.24 0.55 4.06e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs1514658 0.903 rs7661210 chr4:119280167 G/T cg21605333 chr4:119757512 SEC24D -0.51 -4.52 -0.38 1.43e-5 Congenital heart disease (maternal effect); TGCT cis rs875971 0.862 rs11763189 chr7:65983529 G/A cg11764359 chr7:65958608 NA 0.58 5.34 0.43 4.22e-7 Aortic root size; TGCT cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg08392591 chr16:89556376 ANKRD11 0.55 5.21 0.42 7.49e-7 Multiple myeloma (IgH translocation); TGCT cis rs4319547 0.698 rs10744217 chr12:122942070 A/G cg23029597 chr12:123009494 RSRC2 -0.27 -4.53 -0.38 1.38e-5 Body mass index; TGCT cis rs6809651 0.524 rs6444106 chr3:185811495 C/T cg00760338 chr3:185826511 ETV5 -0.78 -6.3 -0.49 4.82e-9 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs3818285 0.679 rs552419 chr10:111630883 G/T cg00817464 chr10:111662876 XPNPEP1 0.32 5.69 0.46 8.6e-8 Superior crus of antihelix expression; TGCT cis rs2832191 0.646 rs2832210 chr21:30508723 T/G cg24692254 chr21:30365293 RNF160 -0.61 -5.41 -0.44 3.08e-7 Dental caries; TGCT cis rs4795419 1 rs4795419 chr17:38166003 G/A cg17467752 chr17:38218738 THRA 0.55 5.32 0.43 4.76e-7 Monocyte percentage of white cells; TGCT cis rs793571 0.503 rs1427281 chr15:58959273 T/C cg05156742 chr15:59063176 FAM63B 0.51 4.89 0.4 3.1e-6 Schizophrenia; TGCT cis rs9926296 0.609 rs4785709 chr16:89796665 G/A cg27121462 chr16:89883253 FANCA -0.56 -5.28 -0.43 5.47e-7 Vitiligo; TGCT cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg05665937 chr4:1216051 CTBP1 0.25 4.7 0.39 6.84e-6 Obesity-related traits; TGCT cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg10547057 chr6:26987810 LOC100270746;C6orf41 -0.47 -4.88 -0.4 3.15e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7929679 0.840 rs1396890 chr11:34780715 T/C cg18414381 chr11:34642885 EHF -0.23 -4.6 -0.38 1.03e-5 Chronic obstructive pulmonary disease-related biomarkers;Lung disease severity in cystic fibrosis; TGCT cis rs4319547 0.656 rs10773088 chr12:122828069 A/T cg08088222 chr12:122070432 ORAI1 0.26 4.66 0.39 8.01e-6 Body mass index; TGCT cis rs10858047 0.883 rs9308267 chr1:115174843 C/T cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs7914558 0.966 rs3977751 chr10:104920232 A/G cg15744005 chr10:104629667 AS3MT -0.39 -4.74 -0.39 5.81e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12620999 0.941 rs10929213 chr2:238020637 A/G cg23555395 chr2:238036564 NA -0.29 -4.89 -0.4 3e-6 Systemic lupus erythematosus; TGCT cis rs7428 0.545 rs1053561 chr2:85546052 A/G cg03728395 chr2:85555865 TGOLN2 -0.29 -5.21 -0.42 7.53e-7 Ear protrusion; TGCT cis rs7605378 0.528 rs281791 chr2:200850402 A/G cg17644776 chr2:200775616 C2orf69 -0.32 -7.18 -0.54 5.5e-11 Osteoporosis; TGCT cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs5771225 0.505 rs2341111 chr22:50690322 G/C cg16473166 chr22:50639996 SELO 0.72 5.96 0.47 2.39e-8 Late-onset Alzheimer's disease; TGCT cis rs2069837 0.515 rs62449526 chr7:22797667 T/C cg00365470 chr7:22893924 NA -0.61 -4.5 -0.37 1.55e-5 Longevity; TGCT cis rs2832191 0.692 rs2245734 chr21:30359965 C/T cg24692254 chr21:30365293 RNF160 0.96 11.17 0.71 1.77e-20 Dental caries; TGCT cis rs7568458 0.527 rs35416445 chr2:85773659 A/G cg02493740 chr2:85810744 VAMP5 -0.28 -5.26 -0.43 6.1e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7267979 0.903 rs6115101 chr20:25229564 C/A cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3008870 0.920 rs1925413 chr1:67417101 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.91 0.73 2.83e-22 Lymphocyte percentage of white cells; TGCT cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg12310025 chr6:25882481 NA -0.65 -6.72 -0.52 6.03e-10 Blood metabolite levels; TGCT cis rs4319547 0.695 rs10744211 chr12:122931820 A/G cg05707623 chr12:122985044 ZCCHC8 -0.71 -5.49 -0.44 2.16e-7 Body mass index; TGCT cis rs6088580 0.634 rs6088502 chr20:33037644 A/T cg06115741 chr20:33292138 TP53INP2 0.53 4.67 0.39 7.67e-6 Glomerular filtration rate (creatinine); TGCT cis rs9952991 0.941 rs34920518 chr18:12783086 A/G cg23598886 chr18:12777645 NA -0.61 -5.58 -0.45 1.42e-7 Inflammatory skin disease; TGCT cis rs56399783 0.614 rs73047355 chr7:2758145 G/A cg19731401 chr7:2775893 GNA12 0.39 5.36 0.43 3.88e-7 Childhood ear infection; TGCT cis rs17473412 0.677 rs11745493 chr5:122847622 A/G cg15125798 chr5:122621645 NA -0.57 -5.2 -0.42 8.05e-7 Total body bone mineral density; TGCT cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg08280861 chr8:58055591 NA 0.53 5.96 0.47 2.44e-8 Developmental language disorder (linguistic errors); TGCT cis rs651907 0.535 rs34161138 chr3:101510388 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs2239547 0.522 rs9846976 chr3:53007995 T/C cg11645453 chr3:52864694 ITIH4 0.34 5.54 0.45 1.76e-7 Schizophrenia; TGCT cis rs17221829 0.733 rs10830326 chr11:89389110 T/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs17376456 0.825 rs17374166 chr5:93238655 T/C cg25358565 chr5:93447407 FAM172A 1.01 8.13 0.59 3.77e-13 Diabetic retinopathy; TGCT cis rs7666738 0.753 rs10029372 chr4:98859002 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs16867321 0.671 rs17455235 chr2:181476447 G/A cg23363182 chr2:181467187 NA -0.47 -4.93 -0.4 2.56e-6 Obesity; TGCT cis rs1552244 0.554 rs2272122 chr3:10047975 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs2067615 0.579 rs1811458 chr12:107203683 G/A cg15890332 chr12:107067104 RFX4 0.28 5.57 0.45 1.52e-7 Heart rate; TGCT cis rs3772130 0.962 rs9878086 chr3:121488353 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.89 0.4 3.07e-6 Cognitive performance; TGCT cis rs854765 0.624 rs11652144 chr17:17733934 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.16 -0.42 9.57e-7 Total body bone mineral density; TGCT cis rs6138458 0.816 rs2151463 chr20:24911819 A/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs5769765 0.773 rs6520065 chr22:50294470 A/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg07061783 chr6:25882402 NA -0.59 -5.5 -0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg10150615 chr22:24372951 LOC391322 -1.01 -13.1 -0.76 3.84e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8014204 0.762 rs8016389 chr14:75287554 T/C cg06637938 chr14:75390232 RPS6KL1 0.58 5.12 0.42 1.15e-6 Caffeine consumption; TGCT cis rs2075165 0.901 rs759329 chr1:156230936 A/G cg20302342 chr1:156215951 PAQR6 0.39 5.67 0.45 9.49e-8 Tonsillectomy; TGCT cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg12310025 chr6:25882481 NA -0.59 -5.31 -0.43 4.96e-7 Intelligence (multi-trait analysis); TGCT cis rs10875746 0.951 rs4760690 chr12:48563653 G/A cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs7584330 0.738 rs13398506 chr2:238374824 A/G cg14458575 chr2:238380390 NA 0.48 7.62 0.56 5.63e-12 Prostate cancer; TGCT cis rs7847628 0.587 rs4837796 chr9:123610288 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.82 -11.05 -0.7 3.56e-20 Birth weight; TGCT cis rs5769765 0.908 rs9616217 chr22:50318946 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.45 5.05 0.41 1.56e-6 Schizophrenia; TGCT cis rs2404618 0.624 rs4338133 chr8:1477507 T/C cg13402656 chr8:1511478 DLGAP2 -0.37 -6.16 -0.48 9.52e-9 Lung cancer; TGCT cis rs12908161 1.000 rs58416181 chr15:85264461 G/A cg11189052 chr15:85197271 WDR73 0.75 6.29 0.49 5.02e-9 Schizophrenia; TGCT cis rs478304 0.651 rs7110576 chr11:65512057 T/G cg10518572 chr11:65560635 OVOL1 -0.23 -4.52 -0.38 1.42e-5 Acne (severe); TGCT cis rs1472147 1.000 rs3736609 chr7:128509319 G/A cg00260937 chr7:128520193 KCP 0.47 6.74 0.52 5.36e-10 Calcium levels; TGCT trans rs9650657 0.572 rs4841465 chr8:10819854 C/T cg15556689 chr8:8085844 FLJ10661 -0.95 -10.16 -0.67 5.18e-18 Neuroticism; TGCT cis rs4689388 0.782 rs4262051 chr4:6281775 G/A cg25554036 chr4:6271136 WFS1 0.57 7.77 0.57 2.63e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs734999 0.549 rs867436 chr1:2523723 C/T cg18854424 chr1:2615690 NA 0.48 5.7 0.46 8.11e-8 Ulcerative colitis; TGCT cis rs6728642 0.908 rs11901495 chr2:98017804 A/G cg26665480 chr2:98280029 ACTR1B 0.95 5.34 0.43 4.21e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs75686122 0.892 rs79475473 chr8:104610018 A/T cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs950169 0.922 rs11633534 chr15:85124642 C/T cg17173187 chr15:85201210 NMB 0.47 4.87 0.4 3.39e-6 Schizophrenia; TGCT cis rs137699 0.604 rs137702 chr22:39750158 T/C cg01416388 chr22:39784598 NA -0.61 -4.84 -0.4 3.85e-6 IgG glycosylation; TGCT cis rs425277 0.583 rs925905 chr1:2044037 T/C cg03732007 chr1:2071316 PRKCZ -0.26 -5.86 -0.47 3.95e-8 Height; TGCT cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs7681440 0.904 rs28507349 chr4:90767063 G/A cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs2549003 0.966 rs2706386 chr5:131832687 C/T cg21138405 chr5:131827807 IRF1 -0.2 -4.99 -0.41 2.03e-6 Asthma (sex interaction); TGCT cis rs17401966 0.838 rs946503 chr1:10308631 C/G cg19773385 chr1:10388646 KIF1B 0.22 4.78 0.39 4.92e-6 Hepatocellular carcinoma; TGCT cis rs2963155 0.518 rs72801029 chr5:142625806 T/C cg17617527 chr5:142782415 NR3C1 0.88 6.29 0.49 5e-9 Breast cancer; TGCT cis rs4654899 0.758 rs6694455 chr1:21352185 C/T cg01072550 chr1:21505969 NA -0.56 -9.17 -0.64 1.28e-15 Superior frontal gyrus grey matter volume; TGCT cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg06481639 chr22:41940642 POLR3H 0.73 6.72 0.52 5.93e-10 Vitiligo; TGCT cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg07507251 chr3:52567010 NT5DC2 0.49 6.96 0.53 1.74e-10 Bipolar disorder; TGCT cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg06238570 chr21:40685208 BRWD1 0.79 8.63 0.61 2.42e-14 Cognitive function; TGCT cis rs17712049 0.908 rs62447147 chr7:48198596 A/G cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs6835098 0.923 rs7671278 chr4:174095769 A/G cg08422745 chr4:174089978 GALNT7 -0.9 -10.08 -0.67 7.91e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs6089829 0.888 rs4809268 chr20:61675249 C/G cg18188782 chr20:61659543 NA 0.44 4.88 0.4 3.17e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs2013441 0.931 rs12937827 chr17:20033202 G/C cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs6846739 chr4:99016647 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4237845 0.788 rs6581157 chr12:58288793 C/T cg02175503 chr12:58329896 NA 0.5 4.69 0.39 7.13e-6 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg06028808 chr11:68637592 NA 0.55 7.12 0.54 7.56e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 7.8 0.57 2.16e-12 Platelet count; TGCT cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg11890956 chr21:40555474 PSMG1 -0.7 -6.88 -0.53 2.68e-10 Menarche (age at onset); TGCT cis rs1395 0.744 rs9653564 chr2:27472618 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs2180341 1.000 rs13218061 chr6:127653758 G/A cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs12142240 0.698 rs41534051 chr1:46828734 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.51e-8 Menopause (age at onset); TGCT cis rs6782228 1.000 rs35604103 chr3:128334852 C/T cg15113803 chr3:129247119 RHO 0.18 4.56 0.38 1.2e-5 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; TGCT cis rs1348850 0.874 rs2166558 chr2:178373652 G/T cg22681709 chr2:178499509 PDE11A -0.35 -4.55 -0.38 1.27e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs11122272 0.701 rs2790887 chr1:231523724 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs644799 0.542 rs10831417 chr11:95467262 A/G cg25622487 chr11:95524042 FAM76B;CEP57 -0.58 -5.67 -0.45 9.29e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg25036284 chr2:26402008 FAM59B -0.61 -4.9 -0.4 2.92e-6 Gut microbiome composition (summer); TGCT cis rs2204008 0.744 rs2222344 chr12:38406832 T/G cg13010199 chr12:38710504 ALG10B 0.55 4.46 0.37 1.84e-5 Bladder cancer; TGCT cis rs478304 0.934 rs1193496 chr11:65537556 C/T cg17480646 chr11:65405466 SIPA1 -0.45 -5.41 -0.44 3.11e-7 Acne (severe); TGCT cis rs595982 0.546 rs12461075 chr19:49399821 G/A cg21252483 chr19:49399788 TULP2 -0.3 -5.05 -0.41 1.54e-6 Red cell distribution width; TGCT cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs10504390 0.656 rs74776773 chr8:66544150 G/A cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.29e-10 IgG glycosylation; TGCT cis rs35883536 0.647 rs2783703 chr1:101040794 T/C cg10298815 chr1:101004474 GPR88 0.24 4.51 0.38 1.47e-5 Monocyte count; TGCT cis rs6754311 0.731 rs748841 chr2:136558157 C/T cg07169764 chr2:136633963 MCM6 -0.61 -5.61 -0.45 1.25e-7 Mosquito bite size; TGCT cis rs57221529 0.766 rs4245972 chr5:578572 A/G cg09021430 chr5:549028 NA -0.37 -5.16 -0.42 9.7e-7 Lung disease severity in cystic fibrosis; TGCT cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg15687855 chr3:44754131 ZNF502 -0.55 -6.65 -0.51 8.38e-10 Depressive symptoms; TGCT cis rs2153535 0.526 rs1796689 chr6:8536433 A/C cg23788917 chr6:8435910 SLC35B3 0.67 5.94 0.47 2.69e-8 Motion sickness; TGCT cis rs801193 0.839 rs12534943 chr7:66070520 A/G cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs6952808 0.543 rs4719436 chr7:2141239 G/A cg04267008 chr7:1944627 MAD1L1 -0.35 -4.72 -0.39 6.16e-6 Bipolar disorder and schizophrenia; TGCT cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs12220898 0.749 rs10776553 chr10:50482929 C/T cg25968469 chr10:49687287 ARHGAP22 0.25 4.57 0.38 1.14e-5 Inflammatory biomarkers; TGCT cis rs6728302 0.557 rs111524519 chr2:233271763 C/A cg06555452 chr2:233241558 NA 0.35 4.69 0.39 7.05e-6 Height; TGCT cis rs2885056 0.830 rs7259124 chr19:10671664 T/C cg04833646 chr19:10679720 CDKN2D 0.99 9.8 0.66 3.83e-17 Red cell distribution width; TGCT cis rs36051895 0.664 rs10815153 chr9:5092864 G/C cg02405213 chr9:5042618 JAK2 -0.79 -11.01 -0.7 4.39e-20 Pediatric autoimmune diseases; TGCT cis rs751728 0.965 rs2013381 chr6:33763837 C/T cg13859433 chr6:33739653 LEMD2 -0.39 -7.08 -0.54 9.45e-11 Crohn's disease; TGCT cis rs34172651 0.517 rs874484 chr16:24803242 T/C cg06028605 chr16:24865363 SLC5A11 0.4 4.44 0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs9733 0.596 rs72702504 chr1:150635374 G/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs9902453 0.904 rs4547389 chr17:28364768 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs7017914 1.000 rs7017914 chr8:71591203 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs12497850 0.897 rs7373778 chr3:48836392 C/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs57590327 0.503 rs13080520 chr3:81850742 T/C cg07356753 chr3:81810745 GBE1 -0.54 -4.68 -0.39 7.39e-6 Extraversion; TGCT cis rs7100689 0.516 rs10788546 chr10:82034854 T/C cg01528321 chr10:82214614 TSPAN14 0.64 6.22 0.49 6.87e-9 Post bronchodilator FEV1; TGCT trans rs66573146 1.000 rs66519732 chr4:6990569 C/G cg07817883 chr1:32538562 TMEM39B 1.67 8.39 0.6 9.16e-14 Granulocyte percentage of myeloid white cells; TGCT cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg20637647 chr7:64974828 NA -0.91 -5.06 -0.41 1.44e-6 Diabetic kidney disease; TGCT cis rs10851411 0.779 rs61071861 chr15:42710219 G/C cg23803468 chr15:43513504 EPB42 0.27 5.29 0.43 5.45e-7 Glucose homeostasis traits; TGCT trans rs7726839 0.540 rs28364691 chr5:664084 G/A cg11887960 chr12:57824829 NA 1.15 9.91 0.66 2.07e-17 Obesity-related traits; TGCT cis rs2228479 0.850 rs45567439 chr16:89814604 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Vitiligo; TGCT cis rs1008375 0.835 rs9760627 chr4:17651508 C/T cg10189774 chr4:17578691 LAP3 0.6 5.19 0.42 8.2e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs709400 0.633 rs45441198 chr14:104002611 T/C cg12935359 chr14:103987150 CKB -0.35 -5.24 -0.43 6.73e-7 Body mass index; TGCT cis rs10875746 0.904 rs10875750 chr12:48545630 C/T cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs7819412 0.549 rs28887839 chr8:11000413 C/T cg21775007 chr8:11205619 TDH -0.58 -5.5 -0.44 2.07e-7 Triglycerides; TGCT cis rs12042938 0.935 rs1094657 chr1:231773407 G/C cg04892437 chr1:231737901 TSNAX-DISC1 0.45 4.69 0.39 7.15e-6 Neuranatomic and neurocognitive phenotypes; TGCT trans rs57221529 0.709 rs72707024 chr5:667915 G/A cg11887960 chr12:57824829 NA 1.14 9.34 0.64 4.86e-16 Lung disease severity in cystic fibrosis; TGCT cis rs6988636 0.901 rs2602001 chr8:124195974 T/C cg22384356 chr8:124195192 FAM83A 0.38 5.04 0.41 1.59e-6 Urinary uromodulin levels; TGCT cis rs9325144 0.600 rs10785621 chr12:38744912 C/T cg26384229 chr12:38710491 ALG10B 0.61 5.61 0.45 1.26e-7 Morning vs. evening chronotype; TGCT cis rs6121246 0.567 rs6120879 chr20:30202961 T/C cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs56104184 0.775 rs17272700 chr19:49391770 G/A cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs11105298 0.891 rs10858864 chr12:89846230 C/T cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9486719 0.749 rs1009596 chr6:96843688 A/G cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs1865760 0.566 rs9467672 chr6:26083904 C/T cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs17221829 0.733 rs11018689 chr11:89367791 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs2282802 0.651 rs6863474 chr5:139630862 C/T cg01081189 chr5:139537190 NA 0.29 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs614226 0.935 rs7956998 chr12:120994932 G/A cg10072921 chr12:121022843 NA -0.44 -4.74 -0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs6547741 1.000 rs2384654 chr2:27847364 C/T cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs473651 0.904 rs508274 chr2:239337723 G/A cg21699342 chr2:239360505 ASB1 0.18 4.89 0.4 3.05e-6 Multiple system atrophy; TGCT cis rs9372498 0.536 rs72952793 chr6:118892979 T/A cg07617317 chr6:118971624 C6orf204 0.49 5.19 0.42 8.37e-7 Diastolic blood pressure; TGCT cis rs9788721 0.592 rs28564957 chr15:78906107 C/A cg06917634 chr15:78832804 PSMA4 -0.68 -5.56 -0.45 1.59e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT trans rs7824557 0.564 rs2736301 chr8:11236413 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs8020441 0.541 rs2131837 chr14:51154779 A/G cg04730355 chr14:51134070 SAV1 1.28 10.23 0.68 3.46e-18 Cognitive performance; TGCT cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg03161606 chr19:29218774 NA 0.62 6.0 0.47 2e-8 Methadone dose in opioid dependence; TGCT cis rs7267979 0.903 rs2474766 chr20:25246153 A/G cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28374715 0.733 rs9568 chr15:41573612 G/T cg18705301 chr15:41695430 NDUFAF1 -0.83 -13.31 -0.77 1.22e-25 Ulcerative colitis; TGCT cis rs17253792 0.822 rs2147114 chr14:56077118 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs910316 0.783 rs11850751 chr14:75590113 A/T cg08847533 chr14:75593920 NEK9 0.95 10.55 0.69 5.83e-19 Height; TGCT cis rs11209185 0.509 rs9436357 chr1:68452488 C/T cg22082780 chr1:68452167 NA 0.32 5.05 0.41 1.56e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT trans rs1814175 0.616 rs1851848 chr11:49992254 G/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs28595532 0.702 rs72670252 chr4:119337546 A/C cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.87 0.4 3.32e-6 Menopause (age at onset); TGCT cis rs7267979 0.657 rs6107073 chr20:25716363 T/C cg16686733 chr20:25566563 NINL 0.47 4.59 0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2412208 0.585 rs11120824 chr1:7113591 G/A cg20434152 chr1:7120926 CAMTA1 -0.31 -5.04 -0.41 1.6e-6 Survival in sporadic amyotrophic lateral sclerosis; TGCT cis rs789859 0.833 rs9834693 chr3:194383487 G/A cg21106136 chr3:194405973 FAM43A -0.39 -5.15 -0.42 9.92e-7 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs2016266 0.819 rs6580942 chr12:53662624 C/A cg16917193 chr12:54089295 NA 0.69 5.04 0.41 1.62e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs7666738 0.612 rs6830172 chr4:99093947 G/A cg17366294 chr4:99064904 C4orf37 0.71 6.93 0.53 2.04e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2191566 0.639 rs7260075 chr19:44566766 T/C cg03039196 chr19:44506973 ZNF230 0.52 4.45 0.37 1.88e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs4665809 0.887 rs6546716 chr2:26263836 A/G cg25036284 chr2:26402008 FAM59B -0.56 -4.85 -0.4 3.62e-6 Gut microbiome composition (summer); TGCT cis rs1153858 1.000 rs2461701 chr15:45703391 G/A cg14582100 chr15:45693742 SPATA5L1 0.47 5.62 0.45 1.22e-7 Homoarginine levels; TGCT cis rs453301 0.686 rs7814328 chr8:8876229 T/C cg06636001 chr8:8085503 FLJ10661 -0.66 -5.46 -0.44 2.51e-7 Joint mobility (Beighton score); TGCT cis rs7552404 0.924 rs12136754 chr1:76230232 C/A cg10523679 chr1:76189770 ACADM 0.88 9.35 0.64 4.67e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7267979 0.903 rs6115118 chr20:25246734 G/A cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7412746 0.658 rs12090215 chr1:150893660 C/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs899997 0.862 rs12912524 chr15:78952756 G/A cg00061860 chr15:78953028 NA -0.33 -5.94 -0.47 2.65e-8 Coronary artery disease or large artery stroke; TGCT cis rs9814567 1.000 rs9864439 chr3:134298671 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9527 0.521 rs12259163 chr10:104961477 A/G cg15744005 chr10:104629667 AS3MT -0.41 -4.76 -0.39 5.36e-6 Arsenic metabolism; TGCT cis rs9303401 1.000 rs6503877 chr17:56841948 C/T cg12560992 chr17:57184187 TRIM37 0.53 5.44 0.44 2.71e-7 Cognitive test performance; TGCT trans rs13064411 0.542 rs2087130 chr3:113226983 T/A cg00307254 chr3:126706825 PLXNA1 0.34 6.78 0.52 4.36e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs3796352 1.000 rs13091844 chr3:53010271 C/T cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2439831 0.681 rs540388 chr15:43606494 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 6.75 0.52 4.98e-10 Lung cancer in ever smokers; TGCT cis rs9486719 0.948 rs11152953 chr6:96894305 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7523050 0.730 rs77425121 chr1:109417677 C/A cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs6138458 1.000 rs11905625 chr20:24977065 A/C cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs9372498 0.536 rs9320660 chr6:118956827 A/T cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs7772486 0.875 rs2777479 chr6:146309178 C/A cg05347473 chr6:146136440 FBXO30 0.51 4.76 0.39 5.34e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9457247 1.000 rs436707 chr6:167388843 T/C cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs72945132 0.714 rs72947077 chr11:70197431 A/G cg00319359 chr11:70116639 PPFIA1 0.97 7.02 0.53 1.3e-10 Coronary artery disease; TGCT cis rs6740322 0.895 rs6544643 chr2:43560072 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.37 -6.02 -0.48 1.86e-8 Coronary artery disease; TGCT cis rs4595586 0.545 rs7970850 chr12:39397878 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7772486 0.790 rs2247206 chr6:146216184 C/T cg05347473 chr6:146136440 FBXO30 0.5 4.9 0.4 2.94e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs713587 0.646 rs2384061 chr2:25135620 C/T cg01884057 chr2:25150051 NA 0.32 6.29 0.49 4.99e-9 Body mass index in non-asthmatics; TGCT cis rs4925386 0.765 rs6142737 chr20:60919800 C/G cg06026331 chr20:60912101 LAMA5 0.4 6.81 0.52 3.82e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs244731 0.959 rs10037110 chr5:176658066 A/T cg17509989 chr5:176798049 RGS14 -0.62 -7.54 -0.56 8.56e-12 Urate levels in lean individuals; TGCT cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg11890956 chr21:40555474 PSMG1 1.13 12.73 0.75 2.92e-24 Cognitive function; TGCT cis rs6074578 0.679 rs12624951 chr20:139409 G/A cg16931068 chr20:139680 DEFB127 0.27 4.52 0.38 1.4e-5 Hirschsprung disease; TGCT cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg03264133 chr6:25882463 NA -0.57 -6.07 -0.48 1.45e-8 Blood metabolite levels; TGCT cis rs13191362 1.000 rs35754151 chr6:163074867 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.02 7.3 0.55 2.97e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6901004 0.803 rs354531 chr6:111548933 C/T cg15721981 chr6:111408429 SLC16A10 -0.54 -4.65 -0.39 8.38e-6 Blood metabolite levels; TGCT cis rs9325144 0.624 rs10783333 chr12:39118931 A/T cg26384229 chr12:38710491 ALG10B 0.62 5.86 0.47 3.95e-8 Morning vs. evening chronotype; TGCT cis rs875971 0.540 rs4717275 chr7:65265180 C/T cg18876405 chr7:65276391 NA -0.37 -5.85 -0.46 4.19e-8 Aortic root size; TGCT cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg11890956 chr21:40555474 PSMG1 -1.12 -11.72 -0.73 8.04e-22 Cognitive function; TGCT cis rs9303401 0.659 rs36109237 chr17:56653834 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs8070740 0.898 rs9303192 chr17:5324836 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs7829975 0.714 rs59046059 chr8:8670736 C/A cg06636001 chr8:8085503 FLJ10661 0.59 5.03 0.41 1.71e-6 Mood instability; TGCT cis rs10927875 0.691 rs1048261 chr1:16340951 A/T cg21385522 chr1:16154831 NA 0.6 6.34 0.49 3.95e-9 Dilated cardiomyopathy; TGCT cis rs11696845 1.000 rs11696845 chr20:43371320 C/T cg25301532 chr20:43378953 KCNK15 0.4 4.53 0.38 1.37e-5 Obesity-related traits; TGCT cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT cis rs832540 0.931 rs2662040 chr5:56246610 A/G cg12311346 chr5:56204834 C5orf35 0.44 4.71 0.39 6.6e-6 Coronary artery disease; TGCT cis rs7647973 1.000 rs11719762 chr3:49409002 G/C cg07636037 chr3:49044803 WDR6 0.66 5.33 0.43 4.45e-7 Menarche (age at onset); TGCT cis rs7666738 0.800 rs13107147 chr4:99028753 C/T cg05340658 chr4:99064831 C4orf37 0.51 5.82 0.46 4.75e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 0.896 rs2305141 chr2:233684402 A/G cg25237894 chr2:233734115 C2orf82 -0.29 -5.37 -0.43 3.72e-7 Coronary artery disease; TGCT cis rs3849570 0.961 rs10154945 chr3:81833766 A/C cg07356753 chr3:81810745 GBE1 -0.82 -7.62 -0.56 5.6e-12 Waist circumference;Body mass index; TGCT cis rs6570726 0.837 rs419991 chr6:145864212 C/T cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs11711311 1.000 rs9288983 chr3:113488699 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs4765905 0.737 rs2370414 chr12:2368396 A/G cg08884539 chr12:3361725 TSPAN9 -0.26 -4.45 -0.37 1.85e-5 Schizophrenia; TGCT cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg18252515 chr7:66147081 NA -1.26 -7.88 -0.58 1.41e-12 Diabetic kidney disease; TGCT cis rs11688237 0.936 rs4662351 chr2:144559694 G/T cg07409629 chr2:144282743 ARHGAP15 -0.36 -4.59 -0.38 1.05e-5 Chin dimples; TGCT cis rs13191362 1.000 rs13199223 chr6:163001083 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6988636 0.901 rs62521825 chr8:124185786 C/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg24675658 chr1:53192096 ZYG11B -0.75 -9.11 -0.63 1.78e-15 Monocyte count; TGCT cis rs7666738 0.830 rs34313689 chr4:99013689 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3731896 0.706 rs7589023 chr2:220138586 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -0.74 -4.44 -0.37 1.96e-5 Educational attainment; TGCT cis rs10791323 0.569 rs2156680 chr11:133742292 T/G cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg08280861 chr8:58055591 NA 0.36 4.91 0.4 2.81e-6 Developmental language disorder (linguistic errors); TGCT cis rs6545883 0.929 rs2256615 chr2:61679894 C/G cg15711740 chr2:61764176 XPO1 -0.56 -5.1 -0.42 1.23e-6 Tuberculosis; TGCT cis rs9926296 0.712 rs447735 chr16:89734349 T/C cg03388025 chr16:89894329 SPIRE2 -0.34 -4.92 -0.4 2.73e-6 Vitiligo; TGCT cis rs7959452 0.640 rs1598543 chr12:69688757 G/T cg11871910 chr12:69753446 YEATS4 0.63 6.37 0.5 3.34e-9 Blood protein levels; TGCT cis rs1113500 0.748 rs1781048 chr1:108555050 A/T cg22161131 chr1:109420278 GPSM2 0.51 4.58 0.38 1.1e-5 Growth-regulated protein alpha levels; TGCT cis rs2404602 0.647 rs12910081 chr15:77022959 G/C cg23625390 chr15:77176239 SCAPER -0.36 -4.56 -0.38 1.21e-5 Blood metabolite levels; TGCT cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg02725872 chr8:58115012 NA -0.38 -4.79 -0.39 4.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs9486719 1.000 rs11153064 chr6:97021959 A/G cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs9787249 0.957 rs11206754 chr1:40216234 A/G cg20968010 chr1:40505947 CAP1 -0.52 -4.94 -0.41 2.46e-6 Blood protein levels; TGCT trans rs1814175 0.817 rs1851860 chr11:49861310 A/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.37e-11 Height; TGCT cis rs7666738 0.515 rs13434650 chr4:98889886 A/G cg17366294 chr4:99064904 C4orf37 0.63 5.59 0.45 1.38e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs61774743 0.754 rs61774744 chr1:41834444 G/A cg01193554 chr1:41846683 NA 0.41 4.91 0.4 2.84e-6 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.905 rs452770 chr6:145847162 T/C cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4919694 0.908 rs11191523 chr10:104792400 A/G cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg22029157 chr1:209979665 IRF6 -0.6 -6.17 -0.48 8.87e-9 Monobrow; TGCT cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.64 -6.48 -0.5 2e-9 Intelligence (multi-trait analysis); TGCT cis rs6964587 1.000 rs10245095 chr7:91710845 A/G cg17063962 chr7:91808500 NA 0.88 9.63 0.65 9.8e-17 Breast cancer; TGCT trans rs7726839 0.540 rs3792720 chr5:643028 T/G cg11887960 chr12:57824829 NA 1.12 9.19 0.64 1.16e-15 Obesity-related traits; TGCT cis rs7246657 0.943 rs1382357 chr19:37977609 G/A cg03233940 chr19:37894644 NA -0.36 -4.49 -0.37 1.61e-5 Coronary artery calcification; TGCT cis rs597539 0.689 rs596874 chr11:68630874 C/T cg04772025 chr11:68637568 NA -0.55 -5.96 -0.47 2.48e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg01802117 chr1:53393560 SCP2 0.48 5.82 0.46 4.82e-8 Monocyte count; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg11494091 chr17:61959527 GH2 0.56 12.2 0.74 5.55e-23 Prudent dietary pattern; TGCT cis rs10833905 0.680 rs2470327 chr11:23033872 A/C cg06387204 chr11:22647648 FANCF 0.53 4.83 0.4 3.92e-6 Sudden cardiac arrest; TGCT cis rs7726839 0.540 rs72703083 chr5:595365 C/T cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs202629 1 rs202629 chr22:41849975 C/T cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Cannabis dependence symptom count; TGCT cis rs7666738 0.791 rs2865958 chr4:99040732 G/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs853679 0.517 rs9380052 chr6:28064623 A/G cg12963246 chr6:28129442 ZNF389 0.5 4.94 0.41 2.48e-6 Depression; TGCT cis rs6570726 0.818 rs412350 chr6:145852409 T/C cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.27e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4294134 0.608 rs11532803 chr7:135245734 T/A cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs10256972 0.567 rs2960850 chr7:1211649 A/G cg04025307 chr7:1156635 C7orf50 0.24 5.51 0.44 1.98e-7 Longevity;Endometriosis; TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg09177884 chr7:1199841 ZFAND2A -0.61 -6.3 -0.49 4.74e-9 Longevity;Endometriosis; TGCT cis rs6089829 0.855 rs6090203 chr20:61663632 G/A cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs1975974 1.000 rs72842072 chr17:21730703 G/A cg18423549 chr17:21743878 NA -0.55 -5.07 -0.41 1.42e-6 Psoriasis; TGCT cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg22535103 chr8:58192502 C8orf71 0.38 4.55 0.38 1.25e-5 Developmental language disorder (linguistic errors); TGCT trans rs7618501 0.573 rs7634917 chr3:50049299 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.92 -0.67 1.95e-17 Intelligence (multi-trait analysis); TGCT cis rs910316 0.503 rs4903273 chr14:75441795 G/A cg08847533 chr14:75593920 NEK9 -0.63 -6.34 -0.49 3.84e-9 Height; TGCT trans rs9329221 0.741 rs13271489 chr8:9803712 T/C cg15556689 chr8:8085844 FLJ10661 -0.77 -7.11 -0.54 8.03e-11 Neuroticism; TGCT cis rs950169 1.000 rs1818950 chr15:84722521 A/G cg17173187 chr15:85201210 NMB 0.5 5.58 0.45 1.46e-7 Schizophrenia; TGCT cis rs9926296 0.508 rs1558184 chr16:89842374 T/G cg04287289 chr16:89883240 FANCA 0.93 11.73 0.73 7.97e-22 Vitiligo; TGCT cis rs11690935 0.632 rs12998411 chr2:172530707 G/C cg13550731 chr2:172543902 DYNC1I2 0.71 6.19 0.49 8.01e-9 Schizophrenia; TGCT cis rs35146811 0.700 rs866500 chr7:99840461 A/G cg13334819 chr7:99746414 C7orf59 0.81 7.06 0.54 1.04e-10 Coronary artery disease; TGCT cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg19318889 chr4:1322082 MAEA -0.27 -6.59 -0.51 1.12e-9 Longevity; TGCT cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs8072100 0.817 rs9905581 chr17:45547185 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.14 -0.42 1.05e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9916302 0.851 rs11870631 chr17:37645129 C/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs7220401 0.789 rs3760456 chr17:27948844 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.91 -8.83 -0.62 8.43e-15 Coronary artery disease; TGCT cis rs11098499 0.954 rs9998585 chr4:120396802 T/A cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs780096 0.587 rs6760828 chr2:27579231 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.36 4.68 0.39 7.24e-6 Total body bone mineral density; TGCT cis rs7772486 0.840 rs2474355 chr6:146312540 C/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.55 -0.38 1.27e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2688608 0.592 rs11814282 chr10:75490217 T/C cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg12310025 chr6:25882481 NA -0.55 -5.58 -0.45 1.41e-7 Blood metabolite levels; TGCT cis rs7103648 0.695 rs12223593 chr11:47789082 T/G cg20307385 chr11:47447363 PSMC3 0.77 7.25 0.55 3.99e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs362272 0.524 rs3129334 chr4:3368526 T/C cg18352616 chr4:3374830 RGS12 0.23 4.66 0.39 8.19e-6 Serum sulfate level; TGCT cis rs4727027 0.933 rs6464940 chr7:148826309 G/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs459571 0.839 rs10993895 chr9:136887726 C/T cg13789015 chr9:136890014 NCRNA00094 -0.39 -7.09 -0.54 8.9e-11 Platelet distribution width; TGCT cis rs2820315 0.867 rs2644135 chr1:201856256 C/G cg12730843 chr1:201915899 LMOD1 0.28 4.97 0.41 2.15e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2404602 1.000 rs2404602 chr15:77030792 A/G cg22467129 chr15:76604101 ETFA -0.49 -5.53 -0.44 1.82e-7 Blood metabolite levels; TGCT cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs56309584 0.596 rs11649742 chr17:8176415 C/T cg08322244 chr17:8066669 VAMP2 -0.57 -5.31 -0.43 4.89e-7 Initial pursuit acceleration; TGCT cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs11711311 0.824 rs35341324 chr3:113351719 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.75 -6.27 -0.49 5.45e-9 IgG glycosylation; TGCT cis rs35146811 0.555 rs2527896 chr7:99537653 A/G cg13334819 chr7:99746414 C7orf59 -0.6 -5.1 -0.42 1.26e-6 Coronary artery disease; TGCT cis rs9899728 0.539 rs35928207 chr17:73033629 T/G cg27626185 chr17:73056755 KCTD2 -0.97 -7.74 -0.57 3.08e-12 Alzheimer's disease or small vessel stroke; TGCT cis rs12220898 0.749 rs7913851 chr10:50482996 C/G cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs60843830 0.661 rs62116682 chr2:104618 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.54 4.51 0.38 1.45e-5 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2692947 0.673 rs2229169 chr2:96780716 T/G cg22654517 chr2:96458247 NA -0.22 -4.72 -0.39 6.17e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs68170813 0.652 rs116894096 chr7:107178477 G/A cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs523522 0.962 rs11065145 chr12:120947419 A/G cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs826838 0.834 rs2387842 chr12:38736442 T/C cg13010199 chr12:38710504 ALG10B 0.83 6.86 0.52 2.92e-10 Heart rate; TGCT cis rs6088590 1.000 rs6120747 chr20:33449769 T/C cg06115741 chr20:33292138 TP53INP2 0.64 5.1 0.42 1.26e-6 Coronary artery disease; TGCT cis rs6088590 0.561 rs6087600 chr20:33157217 T/C cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs6060987 1 rs6060987 chr20:30427077 T/A cg13852791 chr20:30311386 BCL2L1 0.76 5.67 0.45 9.7e-8 Mean corpuscular volume; TGCT cis rs7914558 0.933 rs2066323 chr10:104871361 A/G cg15744005 chr10:104629667 AS3MT -0.42 -5.21 -0.42 7.57e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg01802117 chr1:53393560 SCP2 0.47 5.68 0.45 8.92e-8 Monocyte count; TGCT cis rs10089 1.000 rs3805612 chr5:127505316 G/A cg19767477 chr5:127420684 SLC12A2 -0.44 -4.56 -0.38 1.2e-5 Ileal carcinoids; TGCT cis rs1691799 0.867 rs1183274 chr12:66732057 C/G cg16791601 chr12:66731901 HELB -0.29 -6.31 -0.49 4.41e-9 White blood cell count (basophil); TGCT cis rs1372520 0.748 rs2737002 chr4:90753180 A/G cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs7208859 0.673 rs75142521 chr17:29240537 G/A cg18442181 chr17:29233375 C17orf42 -0.8 -4.81 -0.4 4.38e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs13191362 1.000 rs34066731 chr6:163011047 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7726839 0.507 rs111707179 chr5:593308 T/A cg09021430 chr5:549028 NA -0.43 -5.83 -0.46 4.57e-8 Obesity-related traits; TGCT cis rs10488031 0.557 rs34429167 chr7:37081417 G/A cg06458904 chr7:36312573 EEPD1 0.56 4.7 0.39 6.79e-6 QT interval; TGCT cis rs7786808 0.615 rs4909209 chr7:158194329 C/T cg01191920 chr7:158217561 PTPRN2 -0.42 -6.25 -0.49 5.89e-9 Obesity-related traits; TGCT cis rs7085104 0.632 rs3781287 chr10:104595420 A/C cg15744005 chr10:104629667 AS3MT -0.42 -5.39 -0.44 3.43e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7267979 0.966 rs2261747 chr20:25261784 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12497850 0.864 rs4513485 chr3:49139966 G/A cg07636037 chr3:49044803 WDR6 0.95 10.21 0.68 3.98e-18 Parkinson's disease; TGCT cis rs425277 1.000 rs196128 chr1:2078444 T/G cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs4901869 0.966 rs12148052 chr14:59338970 C/T cg02291164 chr14:59296302 NA 0.24 4.7 0.39 6.86e-6 Panic disorder; TGCT cis rs7584330 0.617 rs10202195 chr2:238352128 A/G cg14458575 chr2:238380390 NA 0.51 7.51 0.56 1e-11 Prostate cancer; TGCT cis rs1865760 0.566 rs9379825 chr6:26083871 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs6088580 0.601 rs6059827 chr20:33016358 C/T cg06115741 chr20:33292138 TP53INP2 0.53 4.68 0.39 7.4e-6 Glomerular filtration rate (creatinine); TGCT cis rs6570726 0.764 rs4263604 chr6:145916697 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.91 0.4 2.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12497850 1.000 rs12493578 chr3:48730116 C/T cg07636037 chr3:49044803 WDR6 -0.91 -9.89 -0.66 2.37e-17 Parkinson's disease; TGCT trans rs3780486 0.846 rs10758192 chr9:33131651 G/A cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs9291683 0.588 rs3796842 chr4:9995851 A/T cg11266682 chr4:10021025 SLC2A9 0.69 9.03 0.63 2.78e-15 Bone mineral density; TGCT cis rs7208859 0.673 rs73265624 chr17:29232066 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6840360 0.615 rs1962910 chr4:152479392 T/A cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs79387448 0.810 rs75218113 chr2:103239356 C/G cg09003973 chr2:102972529 NA 0.94 5.3 0.43 5.15e-7 Gut microbiota (bacterial taxa); TGCT cis rs910316 0.737 rs91144 chr14:75449517 G/A cg08847533 chr14:75593920 NEK9 -0.82 -8.88 -0.62 6.17e-15 Height; TGCT cis rs9486719 0.948 rs2092095 chr6:96870864 T/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs854765 0.587 rs12936927 chr17:17726965 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.68 -6.51 -0.5 1.66e-9 Total body bone mineral density; TGCT cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT trans rs17685 0.633 rs3801471 chr7:75696188 T/G cg19862616 chr7:65841803 NCRNA00174 0.51 8.63 0.61 2.45e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7119038 0.731 rs28409215 chr11:118679304 G/A cg19308663 chr11:118741387 NA 0.31 6.42 0.5 2.65e-9 Sjögren's syndrome; TGCT cis rs1205863 1.000 rs1205876 chr6:11945675 G/A cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs2153535 0.540 rs9378557 chr6:8517381 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9322193 0.923 rs3924871 chr6:149983216 G/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2072499 0.833 rs2842873 chr1:156204653 C/T cg25208724 chr1:156163844 SLC25A44 0.96 12.29 0.74 3.48e-23 Testicular germ cell tumor; TGCT cis rs6089829 0.962 rs6089825 chr20:61668447 C/T cg08564027 chr20:61660810 NA 0.37 6.57 0.51 1.22e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs2836974 0.966 rs7283420 chr21:40666865 T/C cg11644478 chr21:40555479 PSMG1 0.98 10.34 0.68 1.91e-18 Cognitive function; TGCT cis rs6952808 1.000 rs6952808 chr7:1886535 C/G cg22963979 chr7:1858916 MAD1L1 -0.31 -4.6 -0.38 1.01e-5 Bipolar disorder and schizophrenia; TGCT cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg17554472 chr22:41940697 POLR3H -0.48 -5.15 -0.42 9.89e-7 Vitiligo; TGCT cis rs453301 0.538 rs7830804 chr8:8970762 G/T cg15556689 chr8:8085844 FLJ10661 -0.58 -4.56 -0.38 1.22e-5 Joint mobility (Beighton score); TGCT cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg22618164 chr12:122356400 WDR66 0.6 6.19 0.49 8.01e-9 Mean corpuscular volume; TGCT cis rs763121 0.853 rs5757226 chr22:39070550 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg10150615 chr22:24372951 LOC391322 0.99 10.76 0.69 1.8e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs929354 0.772 rs2023975 chr7:157012096 G/A cg05182265 chr7:156933206 UBE3C -0.41 -9.31 -0.64 5.91e-16 Body mass index; TGCT cis rs2404602 0.655 rs4886824 chr15:76969256 A/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs858239 0.600 rs7789237 chr7:23124713 T/G cg05602783 chr7:23145260 KLHL7 -0.6 -5.02 -0.41 1.76e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2153535 0.580 rs1932279 chr6:8473653 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1018836 0.632 rs7017295 chr8:91482356 C/T cg16814680 chr8:91681699 NA 0.75 8.2 0.59 2.58e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.861 rs35517489 chr1:53304062 G/C cg16325326 chr1:53192061 ZYG11B 0.7 8.24 0.59 2.04e-13 Monocyte count; TGCT cis rs2236918 0.643 rs3121389 chr1:242020264 C/T cg04158730 chr1:242011433 EXO1 0.49 4.6 0.38 1.02e-5 Menopause (age at onset); TGCT cis rs9393777 0.546 rs9366673 chr6:26893329 C/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.65 -6.01 -0.48 1.91e-8 Intelligence (multi-trait analysis); TGCT cis rs7954584 0.567 rs1720037 chr12:122382229 G/T cg21171335 chr12:122356390 WDR66 -0.65 -6.8 -0.52 3.97e-10 Mean corpuscular volume; TGCT cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg25036284 chr2:26402008 FAM59B -0.61 -4.9 -0.4 2.92e-6 Gut microbiome composition (summer); TGCT cis rs7246657 0.943 rs4801759 chr19:37954985 G/A cg18154014 chr19:37997991 ZNF793 0.95 6.63 0.51 9.39e-10 Coronary artery calcification; TGCT cis rs6121246 0.609 rs2377317 chr20:30402502 A/G cg13852791 chr20:30311386 BCL2L1 -0.82 -7.69 -0.57 3.88e-12 Mean corpuscular hemoglobin; TGCT cis rs9534288 0.740 rs7989892 chr13:46630641 C/T cg15192986 chr13:46630673 CPB2 -0.48 -5.6 -0.45 1.29e-7 Blood protein levels; TGCT cis rs17384381 1.000 rs35193119 chr1:85859265 T/C cg16011679 chr1:85725395 C1orf52 0.8 6.51 0.5 1.69e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs5750830 0.594 rs1010170 chr22:39778327 C/T cg05872129 chr22:39784769 NA 0.91 9.47 0.65 2.42e-16 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg13683864 chr3:40499215 RPL14 1.12 12.14 0.74 8.04e-23 Renal cell carcinoma; TGCT cis rs950776 0.616 rs495090 chr15:78870003 A/G cg06917634 chr15:78832804 PSMA4 -0.66 -5.29 -0.43 5.47e-7 Sudden cardiac arrest; TGCT cis rs1348850 0.872 rs13004955 chr2:178398923 A/T cg22681709 chr2:178499509 PDE11A 0.38 4.73 0.39 6.12e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7119038 0.818 rs10892289 chr11:118646003 C/T cg19308663 chr11:118741387 NA 0.31 6.12 0.48 1.14e-8 Sjögren's syndrome; TGCT cis rs56235845 0.694 rs6860069 chr5:176755841 C/T cg06060754 chr5:176797920 RGS14 0.41 6.26 0.49 5.83e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg10802521 chr3:52805072 NEK4 -0.64 -7.63 -0.57 5.3e-12 Electroencephalogram traits; TGCT cis rs2032447 0.867 rs9295683 chr6:26069495 C/T cg12310025 chr6:25882481 NA -0.63 -5.41 -0.44 3.17e-7 Intelligence (multi-trait analysis); TGCT cis rs12579753 0.871 rs10862364 chr12:82201280 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg12310025 chr6:25882481 NA 0.5 5.09 0.42 1.29e-6 Blood metabolite levels; TGCT cis rs6752107 0.967 rs56049444 chr2:234157688 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.89 0.4 3.07e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs514406 0.861 rs4926932 chr1:53247495 C/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs6490294 0.659 rs7294578 chr12:112197837 A/C cg10833066 chr12:111807467 FAM109A 0.32 4.96 0.41 2.25e-6 Mean platelet volume; TGCT cis rs8179 0.700 rs42043 chr7:92247333 A/G cg15732164 chr7:92237376 CDK6 -0.29 -5.02 -0.41 1.77e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs1941023 0.584 rs10897057 chr11:60172273 A/T cg08716584 chr11:60157161 MS4A7 -0.31 -4.69 -0.39 7.18e-6 Congenital heart disease (maternal effect); TGCT cis rs7804356 1.000 rs10272303 chr7:26827815 T/C cg03456212 chr7:26904342 SKAP2 -0.64 -4.88 -0.4 3.16e-6 Type 1 diabetes; TGCT cis rs9394841 0.585 rs9381096 chr6:41821137 C/T cg08135965 chr6:41755394 TOMM6 0.59 4.89 0.4 3.04e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs2288073 1.000 rs6708328 chr2:24412413 A/G cg05570707 chr2:24270316 C2orf44 -0.51 -4.61 -0.38 1e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs617219 0.551 rs2131978 chr5:78613986 G/A cg09550809 chr5:78407562 BHMT -0.37 -5.2 -0.42 7.81e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9733 0.596 rs12077833 chr1:150674333 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.49 0.37 1.63e-5 Tonsillectomy; TGCT cis rs1475911 1.000 rs1475911 chr21:43513480 A/C cg19766460 chr21:43528205 UMODL1;C21orf128 0.53 7.12 0.54 7.61e-11 IgG glycosylation; TGCT cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg10295955 chr4:187884368 NA -0.95 -14.86 -0.8 2.58e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs9952991 0.582 rs658158 chr18:12823402 T/G cg23598886 chr18:12777645 NA 0.54 4.74 0.39 5.88e-6 Inflammatory skin disease; TGCT cis rs6424115 0.708 rs2076343 chr1:24129126 A/G cg15997130 chr1:24165203 NA -0.67 -6.97 -0.53 1.7e-10 Immature fraction of reticulocytes; TGCT cis rs17122693 1.000 rs17122683 chr14:51080422 G/A cg04730355 chr14:51134070 SAV1 1.18 8.2 0.59 2.52e-13 Cognitive performance; TGCT cis rs806795 0.605 rs809871 chr6:26256526 C/G cg13736514 chr6:26305472 NA 0.32 4.85 0.4 3.64e-6 Mosquito bite size; TGCT cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg23708337 chr7:1209742 NA 0.62 5.93 0.47 2.76e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6964587 1.000 rs17164263 chr7:91581566 T/A cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs10875746 0.903 rs58952582 chr12:48458448 T/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs9302065 1.000 rs2389236 chr13:95971477 G/A cg26751094 chr13:95954534 ABCC4 -0.32 -5.34 -0.43 4.22e-7 Blood metabolite levels; TGCT cis rs7412746 0.587 rs3849279 chr1:150944707 T/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.7 0.39 6.76e-6 Melanoma; TGCT cis rs6938 0.514 rs35556055 chr15:75253414 G/A cg10253484 chr15:75165896 SCAMP2 -0.63 -5.78 -0.46 5.71e-8 Breast cancer; TGCT cis rs6912958 0.525 rs242262 chr6:88018057 A/C cg04972856 chr6:88032051 C6orf162;GJB7 0.38 4.46 0.37 1.83e-5 Monocyte percentage of white cells; TGCT cis rs616402 0.527 rs10779737 chr1:10580275 C/G cg17425144 chr1:10567563 PEX14 0.53 7.75 0.57 2.87e-12 Breast size; TGCT cis rs899997 0.906 rs1809415 chr15:79028201 C/T cg04896959 chr15:78267971 NA -0.36 -4.86 -0.4 3.43e-6 Coronary artery disease or large artery stroke; TGCT cis rs13326165 0.663 rs634382 chr3:52482851 A/G cg07884673 chr3:53033167 SFMBT1 -0.39 -4.71 -0.39 6.47e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6831352 0.734 rs1154400 chr4:100010010 C/T cg12011299 chr4:100065546 ADH4 0.38 4.96 0.41 2.29e-6 Alcohol dependence; TGCT cis rs597539 0.652 rs613128 chr11:68638058 G/T cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs10191773 0.535 rs72833432 chr2:113102746 T/C cg07905836 chr2:113190072 RGPD8;RGPD5 0.44 4.62 0.38 9.4e-6 Yeast infection; TGCT cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg03452623 chr4:187889614 NA 0.34 5.24 0.43 6.57e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs17345786 0.520 rs13062677 chr3:101305078 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.54 5.51 0.44 1.99e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.929 rs2955360 chr17:17974887 G/A cg09796270 chr17:17721594 SREBF1 -0.27 -5.16 -0.42 9.67e-7 Total body bone mineral density; TGCT cis rs8072100 0.902 rs12051716 chr17:45582395 G/A cg08085267 chr17:45401833 C17orf57 0.44 4.64 0.38 8.86e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1429606 1.000 rs3910021 chr5:87278744 A/G cg09451457 chr5:87440246 NA 0.72 4.72 0.39 6.19e-6 Number of children (6+ vs. 0 or 1); TGCT cis rs7666738 0.830 rs10005120 chr4:99038200 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9549367 0.789 rs7317558 chr13:113893625 G/A cg18105134 chr13:113819100 PROZ -0.35 -5.89 -0.47 3.46e-8 Platelet distribution width; TGCT cis rs453301 0.574 rs10081437 chr8:8948979 T/C cg15556689 chr8:8085844 FLJ10661 -0.68 -5.53 -0.45 1.78e-7 Joint mobility (Beighton score); TGCT cis rs9814567 1.000 rs3846056 chr3:134227292 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2072499 0.833 rs2842873 chr1:156204653 C/T cg24450063 chr1:156163899 SLC25A44 1.02 13.07 0.76 4.58e-25 Testicular germ cell tumor; TGCT cis rs698813 0.604 rs768007 chr2:44487486 G/A cg00619915 chr2:44497795 NA -0.25 -5.7 -0.46 8.4e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs11203032 0.831 rs9651424 chr10:90932935 A/G cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs2458413 1.000 rs2458414 chr8:105355840 A/G cg13045555 chr8:105342365 NA 0.38 5.93 0.47 2.78e-8 Paget's disease; TGCT cis rs950173 1.000 rs13000153 chr2:172586067 A/G cg13550731 chr2:172543902 DYNC1I2 -0.98 -6.05 -0.48 1.57e-8 Hippocampal volume; TGCT cis rs9911578 1.000 rs172565 chr17:56808996 A/T cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs4631830 0.863 rs3101227 chr10:51520203 C/A cg10326726 chr10:51549505 MSMB -0.24 -4.87 -0.4 3.32e-6 Prostate-specific antigen levels; TGCT cis rs1997103 0.911 rs10238738 chr7:55412359 T/C cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1865760 0.508 rs9379820 chr6:26049924 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.1e-11 Height; TGCT cis rs2637266 1.000 rs4979784 chr10:78355476 T/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs7772486 0.875 rs9322044 chr6:146369608 T/C cg23711669 chr6:146136114 FBXO30 0.91 10.09 0.67 7.53e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs35883536 0.669 rs1932352 chr1:101161251 G/A cg06223162 chr1:101003688 GPR88 -0.38 -6.28 -0.49 5.1e-9 Monocyte count; TGCT cis rs11172134 0.508 rs10876967 chr12:57570593 G/A cg19258868 chr12:57585184 LRP1 -0.31 -5.76 -0.46 6.18e-8 Urate levels in overweight individuals; TGCT cis rs10940138 0.774 rs57209938 chr5:67234233 A/G ch.5.1281357F chr5:67228439 NA 0.39 4.66 0.39 8.11e-6 Menarche (age at onset); TGCT cis rs13256369 1.000 rs10098234 chr8:8576692 G/A cg18904891 chr8:8559673 CLDN23 0.63 5.82 0.46 4.83e-8 Obesity-related traits; TGCT cis rs8031584 0.736 rs11635775 chr15:31160640 A/G cg14829155 chr15:31115871 NA -0.37 -4.86 -0.4 3.46e-6 Huntington's disease progression; TGCT cis rs1371867 0.875 rs1788176 chr8:101332112 A/G cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs6674176 0.628 rs3791116 chr1:44414156 T/A cg12908607 chr1:44402522 ARTN -0.67 -8.15 -0.59 3.4e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs908922 0.676 rs545418 chr1:152497338 C/T cg20991723 chr1:152506922 NA 0.46 6.26 0.49 5.7e-9 Hair morphology; TGCT cis rs711245 0.574 rs1179494 chr2:36809496 C/G cg10546459 chr2:36825355 FEZ2 -0.53 -4.6 -0.38 1.02e-5 Height; TGCT cis rs13108904 0.557 rs1680041 chr4:1238521 C/T cg19318889 chr4:1322082 MAEA -0.2 -4.91 -0.4 2.8e-6 Obesity-related traits; TGCT cis rs2708977 0.966 rs2708978 chr2:97202243 A/C cg01950434 chr2:97203154 ARID5A -0.69 -6.36 -0.5 3.5e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT trans rs7819412 0.783 rs28722721 chr8:10948968 G/A cg15556689 chr8:8085844 FLJ10661 -0.79 -7.44 -0.56 1.43e-11 Triglycerides; TGCT cis rs10489202 0.608 rs10918827 chr1:168077044 A/G cg24449463 chr1:168025552 DCAF6 0.49 5.06 0.41 1.49e-6 Schizophrenia; TGCT cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs10193935 0.901 rs2374405 chr2:42479874 A/C cg27598129 chr2:42591480 NA -0.39 -5.41 -0.44 3.06e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9733 0.596 rs11582840 chr1:150688487 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs1056107 0.898 rs7021564 chr9:115002314 C/A cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs42648 0.935 rs42668 chr7:89986525 A/C cg25739043 chr7:89950458 NA -0.65 -6.22 -0.49 6.96e-9 Homocysteine levels; TGCT cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg08280861 chr8:58055591 NA 0.53 6.52 0.51 1.63e-9 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.505 rs7543239 chr1:53162416 A/G cg08859206 chr1:53392774 SCP2 -0.34 -4.74 -0.39 5.77e-6 Monocyte count; TGCT cis rs1971762 0.509 rs10783592 chr12:54037430 G/A cg16917193 chr12:54089295 NA 1.02 11.48 0.72 3.1e-21 Height; TGCT cis rs801193 1.000 rs2659909 chr7:66160279 G/A cg00343986 chr7:65444356 GUSB 0.22 4.87 0.4 3.28e-6 Aortic root size; TGCT cis rs9457247 1.000 rs394522 chr6:167398071 A/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.28e-6 Crohn's disease; TGCT cis rs13118159 0.934 rs4974608 chr4:1356780 C/T cg22683308 chr4:1340831 KIAA1530 -0.68 -6.42 -0.5 2.62e-9 Longevity; TGCT cis rs651907 0.557 rs35850993 chr3:101437433 A/G cg12386194 chr3:101231763 SENP7 0.49 4.69 0.39 7.17e-6 Colorectal cancer; TGCT cis rs853679 0.517 rs11552219 chr6:28126834 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7043114 0.525 rs7853859 chr9:95151377 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.47 -4.82 -0.4 4.1e-6 Height; TGCT cis rs7809950 1.000 rs2520260 chr7:107172794 A/G cg23024343 chr7:107201750 COG5 -0.35 -5.55 -0.45 1.67e-7 Coronary artery disease; TGCT cis rs7552404 0.960 rs12134854 chr1:76137606 A/G cg10523679 chr1:76189770 ACADM 0.92 10.26 0.68 3.03e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs34526934 0.566 rs35563571 chr2:177044459 T/G cg26754761 chr2:177040938 NA -0.29 -5.43 -0.44 2.88e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs904251 0.523 rs10947675 chr6:37479972 G/A cg01843034 chr6:37503916 NA -0.54 -7.03 -0.53 1.2e-10 Cognitive performance; TGCT cis rs2777491 0.507 rs34040639 chr15:41760807 A/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -17.19 -0.84 1.29e-34 Ulcerative colitis; TGCT cis rs7666738 0.830 rs1456208 chr4:98678563 C/T cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.41e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs1973993 0.691 rs1980683 chr1:96890379 A/G cg10631902 chr5:14652156 NA 0.4 10.92 0.7 7.4e-20 Weight; TGCT cis rs938554 0.513 rs3775946 chr4:9995256 A/G cg00071950 chr4:10020882 SLC2A9 0.56 4.67 0.39 7.85e-6 Blood metabolite levels; TGCT cis rs6866344 0.697 rs11748495 chr5:178130000 A/G cg03877680 chr5:178157825 ZNF354A -0.76 -6.1 -0.48 1.23e-8 Neutrophil percentage of white cells; TGCT cis rs8030485 0.728 rs4778886 chr15:79389019 T/C cg17916960 chr15:79447300 NA 0.34 4.64 0.38 8.89e-6 Left ventricle wall thickness; TGCT cis rs2288884 1.000 rs11669540 chr19:52549739 C/A cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs11711311 1.000 rs1043132 chr3:113528689 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.83 -0.52 3.44e-10 IgG glycosylation; TGCT cis rs11030122 0.702 rs2898947 chr11:3977572 G/A cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs4478858 0.647 rs11577679 chr1:31726185 T/C cg00250761 chr1:31883323 NA -0.28 -5.01 -0.41 1.86e-6 Alcohol dependence; TGCT cis rs7027203 0.576 rs7874836 chr9:96559370 C/T cg13679303 chr9:96623674 NA -0.55 -7.82 -0.57 2e-12 DNA methylation (variation); TGCT cis rs950169 0.922 rs4842940 chr15:84831225 C/T cg11189052 chr15:85197271 WDR73 -0.8 -6.36 -0.5 3.52e-9 Schizophrenia; TGCT trans rs9593057 0.892 rs116976730 chr13:35746621 A/G cg01625621 chr15:34260433 AVEN;CHRM5 0.5 7.01 0.53 1.35e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs71636778 0.509 rs17162339 chr1:27252823 A/C cg23921621 chr1:27994728 IFI6 0.43 4.61 0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs9303401 0.659 rs7225896 chr17:56637337 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs2455799 0.559 rs1947147 chr3:15903002 G/A cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs4786125 0.587 rs12709158 chr16:6925056 A/G cg03623568 chr16:6915990 A2BP1 -0.41 -6.41 -0.5 2.69e-9 Heart rate variability traits (SDNN); TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.08e-7 Lymphocyte counts; TGCT cis rs10791097 0.694 rs1050071 chr11:130747231 C/G cg12179176 chr11:130786555 SNX19 0.88 10.19 0.67 4.45e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3770081 1.000 rs59947468 chr2:86289436 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs9486715 0.809 rs9486467 chr6:96971803 C/T cg18709589 chr6:96969512 KIAA0776 0.83 8.13 0.59 3.67e-13 Headache; TGCT cis rs6940638 0.662 rs6915678 chr6:27235866 T/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.44 -4.51 -0.38 1.47e-5 Intelligence (multi-trait analysis); TGCT cis rs6671200 1.000 rs259346 chr1:95728746 G/T cg26537280 chr1:95699037 RWDD3 0.7 5.55 0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs9914544 0.591 rs9900052 chr17:18699398 G/A cg26306683 chr17:18585705 ZNF286B 0.53 4.83 0.4 3.97e-6 Educational attainment (years of education); TGCT cis rs903263 0.932 rs10782824 chr1:84670584 T/A cg09664975 chr1:84543551 PRKACB 0.48 4.56 0.38 1.2e-5 Breast cancer (male); TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg16325326 chr1:53192061 ZYG11B -0.59 -6.94 -0.53 1.89e-10 Monocyte count; TGCT cis rs6690583 0.524 rs12045710 chr1:85451765 T/C cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs2777491 0.574 rs72739644 chr15:41719706 A/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -17.17 -0.84 1.44e-34 Ulcerative colitis; TGCT cis rs9368481 0.645 rs10456350 chr6:26975581 A/C cg07220782 chr6:26987966 LOC100270746;C6orf41 0.52 5.88 0.47 3.64e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs644799 0.965 rs11021310 chr11:95502106 A/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.46 0.6 6.27e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs737008 0.960 rs11640295 chr16:11390728 C/G cg00044050 chr16:11439710 C16orf75 0.79 8.15 0.59 3.4e-13 Obesity-related traits; TGCT cis rs1862618 0.613 rs252889 chr5:56227069 C/A cg24531977 chr5:56204891 C5orf35 -0.68 -7.22 -0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs4808199 0.847 rs34647936 chr19:19548239 T/G cg03709012 chr19:19516395 GATAD2A 0.98 7.76 0.57 2.68e-12 Nonalcoholic fatty liver disease; TGCT cis rs12142240 0.698 rs17357711 chr1:46829013 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7666738 1.000 rs13106934 chr4:99028685 C/T cg17366294 chr4:99064904 C4orf37 0.76 7.12 0.54 7.6e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9926296 0.643 rs12596429 chr16:89841374 T/C cg03388025 chr16:89894329 SPIRE2 0.35 5.15 0.42 1e-6 Vitiligo; TGCT cis rs4149178 0.656 rs11753396 chr6:43290742 A/C cg12269535 chr6:43142014 SRF 0.61 5.14 0.42 1.02e-6 Urate levels; TGCT trans rs7088591 0.702 rs10491208 chr10:59703352 C/G cg11531339 chr2:20069134 NA 0.76 7.09 0.54 9.03e-11 Blood pressure; TGCT cis rs9436747 0.641 rs1938487 chr1:66047267 T/C cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.03 0.41 1.69e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs1008375 0.966 rs2872957 chr4:17651757 C/A cg18681998 chr4:17616180 MED28 1.06 12.43 0.74 1.57e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7208859 0.673 rs450585 chr17:28951039 G/A cg19761014 chr17:28927070 LRRC37B2 0.53 4.64 0.38 8.86e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.712 rs34043080 chr4:99008748 G/C cg18180107 chr4:99064573 C4orf37 0.51 4.69 0.39 7.09e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8077577 0.895 rs11655588 chr17:18107451 C/T cg09161412 chr17:18057145 MYO15A 0.67 5.44 0.44 2.79e-7 Obesity-related traits; TGCT cis rs832540 0.931 rs832535 chr5:56213334 C/T cg24531977 chr5:56204891 C5orf35 -0.52 -5.18 -0.42 8.65e-7 Coronary artery disease; TGCT cis rs916888 0.773 rs199448 chr17:44809001 A/G cg17911788 chr17:44343683 NA -0.6 -6.35 -0.5 3.68e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2276314 1.000 rs56050783 chr18:33553791 A/G cg05985134 chr18:33552581 C18orf21 0.54 4.82 0.4 4.12e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg10150615 chr22:24372951 LOC391322 0.78 8.65 0.61 2.21e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4727027 0.901 rs1534197 chr7:148771970 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.99 0.41 2.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6964587 1.000 rs2282974 chr7:91761617 G/A cg17063962 chr7:91808500 NA 0.89 9.51 0.65 1.9e-16 Breast cancer; TGCT cis rs763014 0.898 rs916414 chr16:632073 C/T cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg06634786 chr22:41940651 POLR3H 0.87 8.16 0.59 3.1400000000000003e-13 Vitiligo; TGCT trans rs7613875 0.543 rs34034116 chr3:49959156 C/A cg21659725 chr3:3221576 CRBN 0.68 7.62 0.56 5.76e-12 Body mass index; TGCT trans rs11722228 0.522 rs881641 chr4:10133747 G/A cg26043149 chr18:55253948 FECH 1.24 14.21 0.79 8.82e-28 Gout;Urate levels;Serum uric acid levels; TGCT cis rs1322512 0.796 rs1744391 chr6:152936761 A/G cg03415253 chr6:152958462 SYNE1 -0.54 -5.01 -0.41 1.83e-6 Tonometry; TGCT cis rs2637266 1.000 rs7475686 chr10:78358761 T/C cg18941641 chr10:78392320 NA 0.39 4.87 0.4 3.29e-6 Pulmonary function; TGCT cis rs250677 0.522 rs6580590 chr5:148360374 C/T cg18129178 chr5:148520854 ABLIM3 0.36 4.69 0.39 7.23e-6 Breast cancer; TGCT cis rs7020830 0.867 rs1339553 chr9:37266123 C/G cg14294708 chr9:37120828 ZCCHC7 1.23 15.94 0.82 8.25e-32 Schizophrenia; TGCT cis rs12802200 0.561 rs746707 chr11:571984 C/T cg27205902 chr11:1006985 AP2A2 0.27 4.47 0.37 1.76e-5 Systemic lupus erythematosus; TGCT cis rs9388451 0.839 rs3757217 chr6:126069636 G/C cg05901451 chr6:126070800 HEY2 -1.04 -15.8 -0.82 1.76e-31 Brugada syndrome; TGCT cis rs6500602 0.627 rs3848372 chr16:4587875 C/A cg08645402 chr16:4508243 NA 0.21 5.5 0.44 2.09e-7 Schizophrenia; TGCT cis rs7552404 0.924 rs1313071 chr1:76195542 C/G cg22875332 chr1:76189707 ACADM 0.72 9.02 0.63 2.88e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13190036 1.000 rs3733875 chr5:176637240 G/T cg18465082 chr5:176734745 MXD3 0.32 4.46 0.37 1.78e-5 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs9611519 0.929 rs12484971 chr22:41439304 A/T cg13695892 chr22:41940480 POLR3H -0.55 -4.9 -0.4 2.99e-6 Neuroticism; TGCT cis rs17221829 0.733 rs10830329 chr11:89390612 A/G cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs7267979 0.789 rs6076347 chr20:25398790 C/T cg03522245 chr20:25566470 NINL -0.52 -5.26 -0.43 6.07e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6121246 0.529 rs6060195 chr20:30185638 C/T cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs6684514 1.000 rs12122180 chr1:156244559 G/A cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT trans rs1005277 0.579 rs2472181 chr10:38386764 T/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs4072705 0.586 rs7869042 chr9:127246751 C/T cg13476313 chr9:127244764 NR5A1 -0.3 -5.17 -0.42 8.97e-7 Menarche (age at onset); TGCT cis rs7208859 0.623 rs28433704 chr17:29084285 G/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11105298 0.891 rs11105325 chr12:89938590 G/A cg00757033 chr12:89920650 WDR51B 0.29 4.49 0.37 1.58e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs4819052 0.959 rs9976074 chr21:46655638 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.69 5.28 0.43 5.61e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6952808 0.792 rs12531315 chr7:1953650 C/G cg04267008 chr7:1944627 MAD1L1 -0.38 -5.12 -0.42 1.12e-6 Bipolar disorder and schizophrenia; TGCT cis rs36051895 0.659 rs7036476 chr9:5063664 T/C cg02405213 chr9:5042618 JAK2 -0.8 -11.47 -0.72 3.33e-21 Pediatric autoimmune diseases; TGCT cis rs6460942 0.915 rs62448619 chr7:12457743 C/T cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs3733585 0.783 rs13148371 chr4:10032561 C/T cg11266682 chr4:10021025 SLC2A9 0.64 8.92 0.63 5e-15 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs7726839 0.540 rs61580655 chr5:597564 A/G cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs9926296 0.605 rs3743859 chr16:89846050 A/G cg27121462 chr16:89883253 FANCA -0.78 -8.32 -0.6 1.37e-13 Vitiligo; TGCT cis rs6461049 0.519 rs3778992 chr7:2175313 C/G cg22963979 chr7:1858916 MAD1L1 -0.34 -5.2 -0.42 8e-7 Schizophrenia; TGCT cis rs1878931 0.624 rs1149492 chr16:3445239 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.45 -0.5 2.3e-9 Body mass index (adult); TGCT trans rs10953454 1.000 rs10247246 chr7:104501165 G/A cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg23205692 chr1:25664452 TMEM50A -0.47 -4.97 -0.41 2.22e-6 Erythrocyte sedimentation rate; TGCT cis rs2921073 0.510 rs2976945 chr8:8270871 G/T cg08975724 chr8:8085496 FLJ10661 0.57 4.92 0.4 2.71e-6 Parkinson's disease; TGCT cis rs986417 1.000 rs1262174 chr14:60887194 C/T cg27398547 chr14:60952738 C14orf39 1.42 9.05 0.63 2.48e-15 Gut microbiota (bacterial taxa); TGCT cis rs114540395 0.925 rs80151341 chr10:103139960 G/A cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs17376456 0.569 rs1026279 chr5:93209581 C/A cg25358565 chr5:93447407 FAM172A -0.81 -6.54 -0.51 1.47e-9 Diabetic retinopathy; TGCT cis rs11209002 0.522 rs2224502 chr1:67539439 A/G cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs2204008 0.774 rs7304438 chr12:38361146 T/G cg13010199 chr12:38710504 ALG10B 0.59 4.58 0.38 1.14e-5 Bladder cancer; TGCT cis rs1045714 0.895 rs1107690 chr7:2640595 G/T cg17215154 chr7:2644645 IQCE 0.28 4.97 0.41 2.2e-6 Urate levels in lean individuals; TGCT cis rs4891159 0.660 rs4891160 chr18:74102135 C/T cg24786174 chr18:74118243 ZNF516 0.56 8.19 0.59 2.75e-13 Longevity; TGCT cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs854765 0.647 rs2974999 chr17:17997547 T/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.68 7.1 0.54 8.35e-11 Total body bone mineral density; TGCT cis rs1552244 0.882 rs13077641 chr3:10022935 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs9902453 1.000 rs4575590 chr17:28361969 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs7224685 0.569 rs35586982 chr17:4001993 G/A cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs2153535 0.580 rs6913100 chr6:8456855 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.1 0.42 1.21e-6 Motion sickness; TGCT cis rs35306767 0.903 rs11253458 chr10:882843 T/C cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs12134133 0.962 rs6668560 chr1:207416807 G/C cg02152968 chr1:207494213 CD55 0.61 4.74 0.39 5.83e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs2692947 0.673 rs2229169 chr2:96780716 T/G cg05933789 chr2:97190408 NA -0.17 -4.87 -0.4 3.39e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs858239 0.600 rs10488077 chr7:23144182 A/T cg05602783 chr7:23145260 KLHL7 -0.73 -6.3 -0.49 4.74e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs367943 1.000 rs348928 chr5:112815295 C/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg00786635 chr1:25594202 NA 0.53 5.58 0.45 1.41e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs6076065 0.707 rs2024746 chr20:23356862 G/A cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT trans rs17685 0.523 rs10246583 chr7:75746667 C/A cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg11062466 chr8:58055876 NA 0.44 4.62 0.38 9.53e-6 Developmental language disorder (linguistic errors); TGCT cis rs317689 0.718 rs315130 chr12:69761444 T/C cg11871910 chr12:69753446 YEATS4 0.55 4.64 0.38 8.6e-6 Response to diuretic therapy; TGCT cis rs3008870 1.000 rs2985817 chr1:67398607 G/C cg03991309 chr1:68237761 GNG12 0.27 4.55 0.38 1.26e-5 Lymphocyte percentage of white cells; TGCT cis rs2228479 0.717 rs12917681 chr16:89810941 C/A cg04287289 chr16:89883240 FANCA 0.74 4.44 0.37 1.99e-5 Skin colour saturation; TGCT cis rs7772486 0.774 rs2247571 chr6:146219533 T/A cg23711669 chr6:146136114 FBXO30 0.77 7.63 0.57 5.28e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs10466239 0.730 rs12221341 chr10:43857330 C/G cg14116799 chr10:43800154 NA -0.55 -4.72 -0.39 6.21e-6 Telomere length; TGCT cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.67 0.66 8.18e-17 Cognitive function; TGCT cis rs7659604 0.540 rs28672860 chr4:122705051 G/A cg05802129 chr4:122689817 NA 0.3 4.46 0.37 1.84e-5 Type 2 diabetes; TGCT cis rs797680 0.856 rs6680107 chr1:93770880 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.1 -0.42 1.24e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1057239 0.510 rs3766694 chr1:175143207 T/C cg00321850 chr1:175162397 KIAA0040 -0.47 -6.88 -0.53 2.66e-10 Diastolic blood pressure; TGCT cis rs17376456 0.877 rs13169675 chr5:93331284 A/G cg25358565 chr5:93447407 FAM172A 0.98 8.48 0.61 5.62e-14 Diabetic retinopathy; TGCT cis rs3820068 0.626 rs11580170 chr1:15909744 C/T cg05660106 chr1:15850417 CASP9 1.04 11.74 0.73 7.33e-22 Systolic blood pressure; TGCT cis rs6840360 0.615 rs12641433 chr4:152607548 A/C cg17479576 chr4:152424074 FAM160A1 -0.63 -6.4 -0.5 2.89e-9 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.867 rs2462750 chr11:93668590 C/T cg26875233 chr11:93583750 C11orf90 -0.46 -5.59 -0.45 1.4e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7659604 0.539 rs2063165 chr4:122750005 A/G cg19748678 chr4:122722346 EXOSC9 0.9 9.1 0.63 1.85e-15 Type 2 diabetes; TGCT cis rs6969780 0.630 rs3735530 chr7:27189982 C/T cg22997113 chr7:27170241 HOXA4 -0.44 -4.46 -0.37 1.79e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs9914988 0.619 rs35477460 chr17:27320276 C/T cg16968985 chr17:27313254 SEZ6 -0.35 -4.47 -0.37 1.75e-5 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs4285028 0.948 rs73855481 chr3:121676951 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg16497277 chr3:49208875 KLHDC8B -0.54 -5.17 -0.42 9.07e-7 Menarche (age at onset); TGCT cis rs36051895 0.593 rs2094619 chr9:5167712 G/C cg02405213 chr9:5042618 JAK2 -0.74 -9.77 -0.66 4.49e-17 Pediatric autoimmune diseases; TGCT cis rs3796352 1.000 rs11718834 chr3:52963668 A/C cg07884673 chr3:53033167 SFMBT1 0.64 6.02 0.48 1.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1775715 0.737 rs2808090 chr10:32143208 A/C cg14930904 chr10:32216787 ARHGAP12 0.55 5.45 0.44 2.63e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6570726 0.577 rs441982 chr6:145842848 A/G cg05347473 chr6:146136440 FBXO30 0.61 5.5 0.44 2.08e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs904251 0.965 rs62406516 chr6:37439364 C/T cg01843034 chr6:37503916 NA -0.46 -5.44 -0.44 2.72e-7 Cognitive performance; TGCT cis rs2688608 0.617 rs6480709 chr10:75479125 T/C cg19442545 chr10:75533431 FUT11 -0.37 -5.87 -0.47 3.81e-8 Inflammatory bowel disease; TGCT cis rs11080107 0.542 rs894606 chr17:27909352 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.58 4.85 0.4 3.67e-6 Coronary artery disease; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg01585852 chr22:24235823 MIF -0.22 -4.85 -0.4 3.67e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1670533 1.000 rs676561 chr4:1083112 C/T cg27284194 chr4:1044797 NA 0.69 5.93 0.47 2.78e-8 Recombination rate (females); TGCT cis rs7726839 0.574 rs72705017 chr5:623733 G/A cg09021430 chr5:549028 NA -0.46 -6.07 -0.48 1.42e-8 Obesity-related traits; TGCT cis rs875971 0.617 rs810400 chr7:66022889 G/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs7552404 0.628 rs4949686 chr1:76473299 G/C cg22875332 chr1:76189707 ACADM 0.66 5.93 0.47 2.83e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs988712 0.705 rs1829469 chr11:27730556 A/G cg10635145 chr11:27742435 BDNF -0.44 -6.2 -0.49 7.51e-9 Obesity; TGCT cis rs2072499 1.000 rs2241108 chr1:156181007 C/G cg06970220 chr1:156163860 SLC25A44 0.67 5.84 0.46 4.32e-8 Testicular germ cell tumor; TGCT cis rs2153535 0.580 rs1034273 chr6:8468145 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs308403 0.600 rs309361 chr4:123657978 A/T cg10495464 chr4:123653540 BBS12;LOC729338 0.73 6.85 0.52 3e-10 Blood protein levels; TGCT cis rs11098499 0.863 rs1552092 chr4:120488496 C/T cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs3892630 0.824 rs34425841 chr19:33231619 C/T cg22980127 chr19:33182716 NUDT19 0.7 4.96 0.41 2.25e-6 Red blood cell traits; TGCT cis rs3091242 0.933 rs7541095 chr1:25761291 T/C cg09222892 chr1:25734099 RHCE -0.43 -7.05 -0.53 1.11e-10 Erythrocyte sedimentation rate; TGCT cis rs903263 0.965 rs6661492 chr1:84592444 T/C cg09664975 chr1:84543551 PRKACB 0.49 4.55 0.38 1.26e-5 Breast cancer (male); TGCT cis rs17253792 0.822 rs118027213 chr14:56039076 T/C cg01858014 chr14:56050164 KTN1 -0.36 -4.57 -0.38 1.15e-5 Putamen volume; TGCT cis rs1403694 0.695 rs10937266 chr3:186433075 G/A cg12454167 chr3:186435060 KNG1 0.5 8.55 0.61 3.86e-14 Blood protein levels; TGCT cis rs611744 0.839 rs672552 chr8:109164223 A/G cg21045802 chr8:109455806 TTC35 0.69 6.06 0.48 1.51e-8 Dupuytren's disease; TGCT cis rs4242434 0.854 rs4872007 chr8:22538879 G/A cg03733263 chr8:22462867 KIAA1967 -1.14 -17.33 -0.84 6.37e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7582180 0.652 rs12997725 chr2:100935136 A/G cg14675211 chr2:100938903 LONRF2 0.51 4.98 0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.632 rs34338978 chr15:77226805 T/C cg22467129 chr15:76604101 ETFA -0.5 -5.65 -0.45 1.06e-7 Blood metabolite levels; TGCT cis rs114540395 0.687 rs75269434 chr10:103473111 G/C cg18276125 chr10:102749041 C10orf2 0.42 5.21 0.42 7.67e-7 Schizophrenia; TGCT cis rs9807989 0.811 rs11689730 chr2:102969984 C/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs8077889 0.719 rs2079006 chr17:41865745 C/G cg26893861 chr17:41843967 DUSP3 1.1 20.06 0.87 9.8e-41 Triglycerides; TGCT trans rs9393366 1.000 rs9393366 chr6:23077311 A/G cg09418321 chr12:4699618 DYRK4 0.28 6.82 0.52 3.59e-10 Tourette syndrome; TGCT cis rs36051895 0.623 rs12720 chr9:5231712 T/A cg02405213 chr9:5042618 JAK2 -0.69 -8.63 -0.61 2.52e-14 Pediatric autoimmune diseases; TGCT cis rs933688 0.536 rs332537 chr5:90794973 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 -0.93 -6.12 -0.48 1.14e-8 Smoking behavior; TGCT cis rs12478296 0.685 rs6705935 chr2:242995110 C/T cg06360820 chr2:242988706 NA -0.62 -5.29 -0.43 5.25e-7 Obesity-related traits; TGCT cis rs57994353 0.793 rs12552167 chr9:139322927 C/T cg13741927 chr9:139327495 INPP5E -0.27 -6.14 -0.48 1.01e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs35306767 0.714 rs67205460 chr10:1090366 C/T cg20503657 chr10:835505 NA 0.6 6.93 0.53 2e-10 Eosinophil percentage of granulocytes; TGCT cis rs13191362 1.000 rs13192894 chr6:163052444 T/A cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.5 0.61 5.17e-14 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4972806 0.776 rs2072589 chr2:177042871 C/T cg14324370 chr2:177042789 NA 0.77 7.09 0.54 9.09e-11 IgG glycosylation; TGCT cis rs910316 0.503 rs12894709 chr14:75441734 G/A cg08847533 chr14:75593920 NEK9 0.67 6.56 0.51 1.31e-9 Height; TGCT cis rs769267 0.930 rs7256149 chr19:19566255 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.73 0.46 7.3e-8 Tonsillectomy; TGCT cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg13395646 chr4:1353034 KIAA1530 -0.36 -4.61 -0.38 9.75e-6 Obesity-related traits; TGCT cis rs4372836 0.504 rs6547881 chr2:29032746 C/T cg09522027 chr2:28974177 PPP1CB 0.57 5.74 0.46 6.84e-8 Body mass index; TGCT cis rs11731606 0.508 rs56943028 chr4:95285813 T/C cg00507259 chr4:95128692 SMARCAD1 0.63 4.72 0.39 6.18e-6 Mean platelet volume; TGCT cis rs6500602 0.893 rs4786490 chr16:4491190 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.29 -5.09 -0.42 1.27e-6 Schizophrenia; TGCT cis rs6988636 1.000 rs6988636 chr8:124185970 A/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2708977 0.637 rs585781 chr2:97088623 C/A cg01950434 chr2:97203154 ARID5A -0.61 -5.26 -0.43 6.08e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg16325326 chr1:53192061 ZYG11B 0.59 6.92 0.53 2.17e-10 Monocyte count; TGCT cis rs473651 0.935 rs482775 chr2:239335403 G/C cg08773314 chr2:239334832 ASB1 0.45 7.58 0.56 7.07e-12 Multiple system atrophy; TGCT cis rs1997103 1.000 rs4947499 chr7:55407196 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2997447 0.761 rs17184884 chr1:26446565 G/A cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs854765 0.583 rs12452254 chr17:17829434 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.77 0.57 2.58e-12 Total body bone mineral density; TGCT cis rs2486012 0.737 rs641356 chr1:44287186 C/T cg12908607 chr1:44402522 ARTN -0.69 -5.35 -0.43 4.16e-7 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.673 rs9907197 chr17:29018263 C/T cg13385521 chr17:29058706 SUZ12P 0.74 4.65 0.39 8.3e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2404602 0.647 rs11072636 chr15:77185786 A/G cg22467129 chr15:76604101 ETFA 0.45 4.53 0.38 1.35e-5 Blood metabolite levels; TGCT cis rs7412746 0.658 rs12067685 chr1:150952917 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 4.68 0.39 7.48e-6 Melanoma; TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg13513804 chr10:50121894 LRRC18;WDFY4 -0.73 -6.64 -0.51 9e-10 Follicular lymphoma; TGCT trans rs1814175 0.817 rs12287396 chr11:49819798 G/C cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs858239 0.537 rs6942981 chr7:23231548 C/T cg05602783 chr7:23145260 KLHL7 -0.73 -5.76 -0.46 6.13e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs4654899 0.865 rs10916927 chr1:21385795 T/C cg01072550 chr1:21505969 NA -0.47 -7.08 -0.54 9.59e-11 Superior frontal gyrus grey matter volume; TGCT cis rs4499344 0.526 rs11084655 chr19:33034698 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.69 5.89 0.47 3.34e-8 Mean platelet volume; TGCT cis rs28595532 0.920 rs116548907 chr4:119735285 G/A cg21605333 chr4:119757512 SEC24D 1.67 8.38 0.6 9.82e-14 Cannabis dependence symptom count; TGCT cis rs151997 0.777 rs3846500 chr5:50254488 A/T cg06027927 chr5:50259733 NA -0.6 -6.47 -0.5 2.04e-9 Callous-unemotional behaviour; TGCT cis rs1971762 0.527 rs7300936 chr12:54030586 C/T cg16917193 chr12:54089295 NA 1.06 11.82 0.73 4.57e-22 Height; TGCT cis rs9583531 0.600 rs2119479 chr13:111371181 A/C cg24331049 chr13:111365604 ING1 0.77 7.38 0.55 1.97e-11 Coronary artery disease; TGCT cis rs2180341 0.842 rs7739679 chr6:127545428 G/A cg27446573 chr6:127587934 RNF146 1.05 8.19 0.59 2.67e-13 Breast cancer; TGCT cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs36051895 0.632 rs62541959 chr9:5175687 G/C cg02405213 chr9:5042618 JAK2 -0.72 -9.73 -0.66 5.69e-17 Pediatric autoimmune diseases; TGCT cis rs6138458 0.847 rs56312312 chr20:24959386 C/A cg26195577 chr20:24973756 C20orf3 1.21 10.66 0.69 3.07e-19 Blood protein levels; TGCT trans rs324780 0.544 rs3112089 chr12:83907973 T/C cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.42e-10 Vertical cup-disc ratio; TGCT cis rs854765 0.594 rs8066560 chr17:17728043 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.66 -6.06 -0.48 1.52e-8 Total body bone mineral density; TGCT cis rs1215050 0.791 rs2123100 chr4:98803747 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13242816 1.000 rs3807987 chr7:116179834 G/A cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs7249142 0.597 rs759999 chr19:19281207 A/C cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.45 -4.5 -0.37 1.53e-5 IgG glycosylation; TGCT cis rs936229 0.861 rs7162232 chr15:75115895 G/A cg10253484 chr15:75165896 SCAMP2 -0.66 -5.34 -0.43 4.28e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg14827481 chr10:134361889 INPP5A 0.31 4.99 0.41 1.99e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7178572 0.568 rs62008452 chr15:77591007 A/G cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs1950500 0.545 rs1950501 chr14:24806800 C/G cg22990158 chr14:24802150 ADCY4 -0.52 -4.63 -0.38 9.25e-6 Height; TGCT cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg02725872 chr8:58115012 NA -0.36 -4.62 -0.38 9.53e-6 Developmental language disorder (linguistic errors); TGCT cis rs1371867 0.846 rs1660345 chr8:101322762 C/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs208515 0.556 rs12201658 chr6:66678457 T/C cg07460842 chr6:66804631 NA 0.87 9.16 0.64 1.32e-15 Exhaled nitric oxide levels; TGCT cis rs2486288 0.656 rs12911861 chr15:45566718 T/C cg26924012 chr15:45694286 SPATA5L1 -0.78 -7.46 -0.56 1.3e-11 Glomerular filtration rate; TGCT cis rs17221829 0.769 rs11018674 chr11:89357113 G/A cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs79057730 0.528 rs6965219 chr7:821807 C/G cg11064039 chr7:766100 PRKAR1B;HEATR2 0.74 5.61 0.45 1.25e-7 Initial pursuit acceleration; TGCT cis rs453301 0.719 rs34004903 chr8:8892604 C/T cg15556689 chr8:8085844 FLJ10661 -0.62 -5.24 -0.43 6.69e-7 Joint mobility (Beighton score); TGCT cis rs2836974 0.583 rs9981884 chr21:40585633 G/A cg11890956 chr21:40555474 PSMG1 0.81 8.43 0.6 7.55e-14 Cognitive function; TGCT cis rs1568889 1.000 rs12797712 chr11:28290890 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 7.99 0.58 7.84e-13 Bipolar disorder; TGCT cis rs644799 0.710 rs523153 chr11:95570961 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.82 7.93 0.58 1.07e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7617773 0.851 rs7647817 chr3:48236507 G/A cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs1799949 0.860 rs8176279 chr17:41210396 A/C cg10047753 chr17:41438598 NA 0.81 7.41 0.55 1.73e-11 Menopause (age at onset); TGCT cis rs6992820 0.967 rs7816303 chr8:56723278 A/G cg06880721 chr8:56792545 LYN -0.53 -4.44 -0.37 1.97e-5 Mean platelet volume; TGCT cis rs7267979 1.000 rs6076345 chr20:25381895 T/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs12477438 0.798 rs1349778 chr2:99645011 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.69 -5.87 -0.47 3.64e-8 Chronic sinus infection; TGCT cis rs4631830 0.863 rs2843550 chr10:51521452 C/T cg10326726 chr10:51549505 MSMB -0.25 -4.86 -0.4 3.46e-6 Prostate-specific antigen levels; TGCT cis rs2742417 0.967 rs2742426 chr3:45735901 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT trans rs1814175 0.791 rs11040513 chr11:49778153 G/C cg03929089 chr4:120376271 NA -0.69 -8.17 -0.59 3.03e-13 Height; TGCT cis rs875971 0.964 rs2161065 chr7:65932905 A/G cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.12e-6 Aortic root size; TGCT cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg25036284 chr2:26402008 FAM59B 0.67 4.46 0.37 1.79e-5 Gut microbiome composition (summer); TGCT cis rs1552244 0.882 rs17050660 chr3:10001772 A/G cg00149659 chr3:10157352 C3orf10 -0.74 -4.7 -0.39 6.84e-6 Alzheimer's disease; TGCT cis rs13108904 0.539 rs13141169 chr4:1340353 C/T cg03303774 chr4:1407052 NA 0.38 6.03 0.48 1.78e-8 Obesity-related traits; TGCT cis rs832540 0.669 rs173764 chr5:56198920 C/T cg12311346 chr5:56204834 C5orf35 -0.59 -6.11 -0.48 1.21e-8 Coronary artery disease; TGCT cis rs9486715 0.867 rs9372106 chr6:96875058 T/C cg18709589 chr6:96969512 KIAA0776 0.77 7.5 0.56 1.09e-11 Headache; TGCT cis rs2295359 1.000 rs11209007 chr1:67619345 C/G cg12940439 chr1:67600707 NA 0.56 6.04 0.48 1.63e-8 Psoriasis; TGCT cis rs7586879 0.828 rs9631061 chr2:25109804 C/T cg01884057 chr2:25150051 NA 0.27 4.8 0.4 4.57e-6 Body mass index; TGCT trans rs10109025 0.701 rs10101292 chr8:10856474 T/C cg06636001 chr8:8085503 FLJ10661 -0.78 -7.02 -0.53 1.26e-10 Joint mobility (Beighton score); TGCT cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7072216 0.763 rs7091709 chr10:100167605 G/A cg26618903 chr10:100175079 PYROXD2 -0.41 -4.5 -0.38 1.51e-5 Metabolite levels; TGCT cis rs916888 0.531 rs183211 chr17:44788310 G/A cg16520312 chr17:43971471 MAPT;LOC100128977 -0.46 -4.43 -0.37 2.01e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs854765 0.927 rs4925138 chr17:17992793 T/G cg04398451 chr17:18023971 MYO15A 0.3 4.68 0.39 7.36e-6 Total body bone mineral density; TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs6860806 0.631 rs6863548 chr5:131575920 G/A cg24060327 chr5:131705240 SLC22A5 -0.59 -5.99 -0.47 2.15e-8 Breast cancer; TGCT cis rs2836950 0.545 rs2836956 chr21:40623018 C/G cg17971929 chr21:40555470 PSMG1 0.55 5.05 0.41 1.55e-6 Menarche (age at onset); TGCT cis rs10927875 0.894 rs10927878 chr1:16319957 C/T cg14742211 chr1:16348397 CLCNKA -0.19 -4.48 -0.37 1.66e-5 Dilated cardiomyopathy; TGCT cis rs1865760 0.820 rs9348697 chr6:25890834 C/T cg16482183 chr6:26056742 HIST1H1C 0.52 4.59 0.38 1.08e-5 Height; TGCT cis rs13202913 0.652 rs9371528 chr6:151832668 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.72 -4.93 -0.4 2.61e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs9583531 0.657 rs9521915 chr13:111384528 C/T cg24331049 chr13:111365604 ING1 0.83 8.23 0.59 2.16e-13 Coronary artery disease; TGCT cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg11890956 chr21:40555474 PSMG1 -0.76 -7.45 -0.56 1.36e-11 Cognitive function; TGCT cis rs3782455 1.000 rs16943542 chr12:114406301 C/T cg10631684 chr12:113795897 PLBD2 -0.8 -5.22 -0.42 7.25e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7809950 0.731 rs4730238 chr7:107054787 G/A cg23024343 chr7:107201750 COG5 -0.48 -6.44 -0.5 2.43e-9 Coronary artery disease; TGCT cis rs7666738 0.830 rs1834645 chr4:98979593 T/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.922 rs4586394 chr15:84822385 G/A cg12863693 chr15:85201151 NMB -0.43 -4.81 -0.4 4.36e-6 Schizophrenia; TGCT cis rs9457247 1.000 rs2013815 chr6:167373812 T/A cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.05e-6 Crohn's disease; TGCT cis rs10875746 0.517 rs12721420 chr12:48358794 C/T cg20731937 chr12:48336164 NA 0.9 6.62 0.51 9.82e-10 Longevity (90 years and older); TGCT cis rs9303401 0.614 rs34941454 chr17:57102742 T/G cg25039879 chr17:56429692 SUPT4H1 0.54 4.8 0.4 4.57e-6 Cognitive test performance; TGCT cis rs10791097 0.694 rs7940027 chr11:130745591 A/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.1e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 6.95 0.53 1.86e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6598955 0.671 rs10902727 chr1:26597781 C/T cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.8e-6 Obesity-related traits; TGCT cis rs422249 0.819 rs174605 chr11:61626921 G/T cg19610905 chr11:61596333 FADS2 -0.56 -4.52 -0.38 1.42e-5 Trans fatty acid levels; TGCT cis rs7552404 0.924 rs1694419 chr1:76219801 C/T cg10523679 chr1:76189770 ACADM 0.7 6.35 0.5 3.77e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2439831 0.681 rs498837 chr15:43608024 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 6.75 0.52 4.98e-10 Lung cancer in ever smokers; TGCT cis rs1371867 0.846 rs1692006 chr8:101252462 C/T cg06002616 chr8:101225028 SPAG1 0.54 6.4 0.5 2.87e-9 Atrioventricular conduction; TGCT cis rs763014 0.865 rs2018789 chr16:632051 T/C cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs9399137 0.507 rs10484496 chr6:135299682 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.76 0.39 5.27e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs769267 0.930 rs3794993 chr19:19611550 G/T cg08509172 chr19:19383838 TM6SF2 -0.35 -4.54 -0.38 1.32e-5 Tonsillectomy; TGCT cis rs2580764 0.624 rs12713284 chr2:55228861 G/A cg09592903 chr2:55203963 RTN4 -0.25 -5.45 -0.44 2.58e-7 Mean platelet volume; TGCT cis rs896854 0.517 rs2013597 chr8:95951807 G/A cg13393036 chr8:95962371 TP53INP1 -0.49 -5.61 -0.45 1.26e-7 Type 2 diabetes; TGCT cis rs12580194 0.593 rs61957941 chr12:55748058 G/A cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs2576037 0.562 rs612519 chr18:44379490 G/A cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.7 -0.39 6.77e-6 Personality dimensions; TGCT cis rs7043114 0.525 rs4744136 chr9:95275024 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.54 5.41 0.44 3.18e-7 Height; TGCT cis rs8072100 0.713 rs11079776 chr17:45546893 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.16 -0.42 9.45e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs709400 0.663 rs1028613 chr14:103888324 G/A cg12935359 chr14:103987150 CKB -0.36 -5.47 -0.44 2.42e-7 Body mass index; TGCT cis rs2013441 1.000 rs2526480 chr17:20130074 A/G cg23224458 chr17:20280056 CCDC144C 0.4 4.7 0.39 6.74e-6 Obesity-related traits; TGCT cis rs6570726 0.791 rs1280276 chr6:145892350 A/C cg23711669 chr6:146136114 FBXO30 0.89 9.87 0.66 2.56e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs933688 1.000 rs1895448 chr5:90743854 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.1 10.42 0.68 1.18e-18 Smoking behavior; TGCT cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg23758822 chr17:41437982 NA 0.73 6.74 0.52 5.43e-10 Menopause (age at onset); TGCT cis rs11605924 0.692 rs877412 chr11:45897651 A/C ch.11.939596F chr11:45881766 CRY2 0.44 5.51 0.44 2.02e-7 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs1799949 1.000 rs8176212 chr17:41226601 G/C cg23758822 chr17:41437982 NA 0.72 6.77 0.52 4.51e-10 Menopause (age at onset); TGCT cis rs13118159 0.801 rs7690727 chr4:1340811 C/A cg05025164 chr4:1340916 KIAA1530 0.54 4.79 0.4 4.64e-6 Longevity; TGCT cis rs2463822 1.000 rs2513052 chr11:62108248 C/G cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs11098499 0.644 rs3806808 chr4:120551085 A/C cg09307838 chr4:120376055 NA 0.62 5.82 0.46 4.83e-8 Corneal astigmatism; TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg16325326 chr1:53192061 ZYG11B 0.56 6.29 0.49 4.85e-9 Monocyte count; TGCT cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs858239 0.636 rs7808488 chr7:23221870 T/C cg05602783 chr7:23145260 KLHL7 -0.64 -5.31 -0.43 4.98e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6545883 0.929 rs55806663 chr2:61740487 G/T cg15711740 chr2:61764176 XPO1 -0.56 -5.11 -0.42 1.17e-6 Tuberculosis; TGCT cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs7829975 0.510 rs332037 chr8:8722675 C/T cg08975724 chr8:8085496 FLJ10661 0.57 5.23 0.43 7.02e-7 Mood instability; TGCT trans rs3780486 1.000 rs3780480 chr9:33163486 G/T cg20290983 chr6:43655470 MRPS18A 1.1 10.66 0.69 3.1400000000000002e-19 IgG glycosylation; TGCT cis rs2562456 0.793 rs7259708 chr19:21750648 T/C cg01304269 chr19:21688519 ZNF429 0.58 4.73 0.39 5.93e-6 Pain; TGCT cis rs77861329 1.000 rs164639 chr3:52210872 A/G cg08692210 chr3:52188851 WDR51A -0.83 -5.04 -0.41 1.58e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs514406 0.861 rs2065477 chr1:53250213 C/T cg01802117 chr1:53393560 SCP2 -0.46 -5.57 -0.45 1.49e-7 Monocyte count; TGCT cis rs1532993 0.518 rs9990450 chr4:98568821 C/A cg05340658 chr4:99064831 C4orf37 -0.38 -4.53 -0.38 1.36e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6951245 0.554 rs76243429 chr7:1152543 C/T cg03188948 chr7:1209495 NA 0.5 5.23 0.42 7.12e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs77633900 0.614 rs2170998 chr15:77007159 C/T cg21673338 chr15:77095150 SCAPER 0.51 5.12 0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs9467773 1.000 rs6456734 chr6:26566965 G/T cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.629 rs4851295 chr2:100945605 T/C cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7119 0.635 rs2667767 chr15:77876031 T/C cg27398640 chr15:77910606 LINGO1 0.31 6.19 0.49 8.16e-9 Type 2 diabetes; TGCT cis rs7945705 0.935 rs2568061 chr11:8886260 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.48 -5.5 -0.44 2.03e-7 Hemoglobin concentration; TGCT cis rs875971 0.895 rs778700 chr7:65866450 C/T cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs1371867 0.764 rs1020171 chr8:101288610 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -6.83 -0.52 3.32e-10 Atrioventricular conduction; TGCT trans rs877282 0.891 rs11599917 chr10:762288 G/A cg22713356 chr15:30763199 NA 1.15 8.97 0.63 3.86e-15 Uric acid levels; TGCT cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg06481639 chr22:41940642 POLR3H 0.7 6.16 0.48 9.5e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs68170813 0.562 rs78181351 chr7:106999301 A/G cg02696742 chr7:106810147 HBP1 -0.73 -5.95 -0.47 2.6e-8 Coronary artery disease; TGCT trans rs629535 0.814 rs56301437 chr8:70108518 C/T cg21567404 chr3:27674614 NA -0.57 -8.81 -0.62 9.34e-15 Dupuytren's disease; TGCT cis rs7954584 0.567 rs1720037 chr12:122382229 G/T cg13699009 chr12:122356056 WDR66 -0.28 -5.7 -0.46 8.42e-8 Mean corpuscular volume; TGCT cis rs67311347 0.955 rs73080163 chr3:40533061 G/T cg02782426 chr3:40428986 ENTPD3 0.44 4.74 0.39 5.88e-6 Renal cell carcinoma; TGCT cis rs11167764 1.000 rs11167764 chr5:141479065 A/C cg23435118 chr5:141488016 NDFIP1 -0.28 -4.49 -0.37 1.58e-5 Crohn's disease; TGCT cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg19635926 chr16:89946313 TCF25 0.28 4.82 0.4 4.06e-6 Skin colour saturation; TGCT cis rs7192750 0.586 rs8044342 chr16:71869532 A/G cg06353428 chr16:71660113 MARVELD3 0.76 6.74 0.52 5.2400000000000005e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs12950390 0.853 rs17700008 chr17:45863591 A/C cg24803719 chr17:45855879 NA 0.49 5.03 0.41 1.64e-6 IgG glycosylation; TGCT cis rs36051895 0.632 rs2149552 chr9:5132838 A/G cg02405213 chr9:5042618 JAK2 -0.73 -10.16 -0.67 5.11e-18 Pediatric autoimmune diseases; TGCT cis rs1580019 0.961 rs1868777 chr7:32494076 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.77 6.09 0.48 1.33e-8 Cognitive ability; TGCT cis rs9303401 0.614 rs35057477 chr17:57097064 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.83 0.46 4.4e-8 Cognitive test performance; TGCT cis rs1044826 0.642 rs9826544 chr3:139162831 A/G cg00490450 chr3:139108681 COPB2 0.53 4.59 0.38 1.06e-5 Obesity-related traits; TGCT cis rs904251 0.828 rs2797803 chr6:37487340 T/C cg01843034 chr6:37503916 NA -0.52 -6.28 -0.49 5.17e-9 Cognitive performance; TGCT cis rs4820539 1.000 rs2267003 chr22:23457098 A/G cg14186256 chr22:23484241 RTDR1 1.0 12.29 0.74 3.48e-23 Bone mineral density; TGCT cis rs1018836 0.663 rs2205151 chr8:91483468 A/C cg16814680 chr8:91681699 NA -0.81 -8.41 -0.6 8.09e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs561341 0.739 rs9906455 chr17:30215669 G/A cg13647721 chr17:30228624 UTP6 -0.61 -4.8 -0.4 4.39e-6 Hip circumference adjusted for BMI; TGCT cis rs2847281 0.587 rs2542152 chr18:12782761 C/T cg23598886 chr18:12777645 NA -0.36 -4.6 -0.38 1.05e-5 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs2290416 0.584 rs3816477 chr8:144685271 T/C cg17524265 chr8:144659883 NAPRT1 -0.65 -5.23 -0.43 7.03e-7 Attention deficit hyperactivity disorder; TGCT cis rs6740322 0.948 rs6715072 chr2:43562230 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.32 -0.49 4.21e-9 Coronary artery disease; TGCT trans rs1814175 0.817 rs1818890 chr11:49856882 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs6430585 0.583 rs3769013 chr2:136556182 C/T cg07169764 chr2:136633963 MCM6 1.22 11.84 0.73 4.08e-22 Corneal structure; TGCT cis rs2228479 0.557 rs62056064 chr16:89903843 G/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg21672276 chr3:44754072 ZNF502 -0.41 -4.68 -0.39 7.51e-6 Depressive symptoms; TGCT cis rs3820928 1.000 rs10193316 chr2:227777650 A/G cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs4077468 1.000 rs4077468 chr1:205914757 A/G cg24503407 chr1:205819492 PM20D1 -0.39 -4.59 -0.38 1.07e-5 Cystic fibrosis-related diabetes; TGCT cis rs3733585 0.699 rs6449172 chr4:9966036 A/T cg00071950 chr4:10020882 SLC2A9 -0.57 -6.85 -0.52 3.12e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7312933 0.558 rs55702525 chr12:42814309 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.69 -0.46 8.61e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs797680 0.897 rs3767962 chr1:93814411 A/G cg17826107 chr1:92977322 EVI5 -0.24 -5.74 -0.46 6.97e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2760061 0.846 rs3094912 chr1:228209815 T/A cg18477163 chr1:228402036 OBSCN 0.35 7.47 0.56 1.22e-11 Diastolic blood pressure; TGCT cis rs2067615 0.524 rs10778505 chr12:107143126 G/C cg15890332 chr12:107067104 RFX4 0.29 5.88 0.47 3.53e-8 Heart rate; TGCT cis rs10875746 1.000 rs10875746 chr12:48518264 A/C cg20731937 chr12:48336164 NA 0.61 4.83 0.4 4.02e-6 Longevity (90 years and older); TGCT cis rs9341808 0.935 rs2298307 chr6:80816296 A/G cg08355045 chr6:80787529 NA 0.29 5.18 0.42 8.61e-7 Sitting height ratio; TGCT cis rs4076764 0.881 rs10917758 chr1:163430652 G/A cg24596788 chr1:163392923 NA -0.17 -4.85 -0.4 3.64e-6 Motion sickness; TGCT cis rs709400 0.628 rs11621510 chr14:103869620 T/C cg12935359 chr14:103987150 CKB -0.36 -5.37 -0.43 3.67e-7 Body mass index; TGCT cis rs7772486 0.701 rs2244308 chr6:146213706 C/T cg23711669 chr6:146136114 FBXO30 0.87 9.99 0.67 1.3e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2034088 0.632 rs8067311 chr17:405603 T/G cg04370829 chr17:406249 NA -0.36 -5.26 -0.43 6.01e-7 Hip circumference adjusted for BMI; TGCT cis rs9467773 0.935 rs1056668 chr6:26510605 C/T cg15659132 chr6:26577336 NA 0.81 10.38 0.68 1.52e-18 Intelligence (multi-trait analysis); TGCT cis rs7834745 0.501 rs12679857 chr8:119977337 A/G cg17171407 chr8:119960777 TNFRSF11B 0.31 5.2 0.42 7.98e-7 Eosinophil counts;Sum eosinophil basophil counts; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg03395511 chr6:291903 DUSP22 -0.7 -7.09 -0.54 9.19e-11 Menopause (age at onset); TGCT cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.08 0.42 1.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs12681287 0.752 rs13256500 chr8:87247063 G/A cg27223183 chr8:87520930 FAM82B -0.83 -5.76 -0.46 6.33e-8 Caudate activity during reward; TGCT cis rs597539 0.652 rs592697 chr11:68650064 G/A cg21963583 chr11:68658836 MRPL21 0.36 6.08 0.48 1.35e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7809950 0.954 rs2520245 chr7:107137428 G/C cg23024343 chr7:107201750 COG5 -0.35 -5.48 -0.44 2.24e-7 Coronary artery disease; TGCT cis rs17401966 0.838 rs1013953 chr1:10319459 T/A cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs5769707 0.681 rs2071902 chr22:50034538 G/C cg06623630 chr22:50017776 C22orf34 -0.27 -4.67 -0.39 7.81e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs3812831 0.643 rs7322339 chr13:114929726 C/A cg08824895 chr13:115047677 UPF3A 0.51 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs7208859 0.623 rs58089675 chr17:29196764 C/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7104764 0.957 rs3817629 chr11:237312 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs9611565 0.879 rs5758311 chr22:41759375 G/T cg03806693 chr22:41940476 POLR3H -1.02 -11.06 -0.7 3.31e-20 Vitiligo; TGCT cis rs9905704 0.624 rs4932691 chr17:57094617 T/C cg12560992 chr17:57184187 TRIM37 -0.58 -5.15 -0.42 9.78e-7 Testicular germ cell tumor; TGCT cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg12310025 chr6:25882481 NA -0.94 -8.97 -0.63 3.8e-15 Intelligence (multi-trait analysis); TGCT cis rs1018836 0.828 rs12548806 chr8:91564256 C/T cg16814680 chr8:91681699 NA -0.75 -7.85 -0.58 1.71e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.592 rs80477 chr22:42001183 C/T cg13695892 chr22:41940480 POLR3H 0.85 7.97 0.58 8.64e-13 Vitiligo; TGCT cis rs79349575 0.783 rs61576918 chr17:46985593 A/C cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs1044826 0.619 rs57357132 chr3:139118358 A/T cg00490450 chr3:139108681 COPB2 -0.53 -4.56 -0.38 1.2e-5 Obesity-related traits; TGCT cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs514406 0.679 rs11206006 chr1:53218380 A/G cg08859206 chr1:53392774 SCP2 0.44 6.63 0.51 9.33e-10 Monocyte count; TGCT cis rs910316 0.967 rs4903285 chr14:75609268 A/T cg08847533 chr14:75593920 NEK9 0.96 10.86 0.7 1.05e-19 Height; TGCT cis rs1372520 0.684 rs356191 chr4:90688120 G/A cg01966878 chr4:90757139 SNCA 0.3 4.82 0.4 4.11e-6 Neuroticism; TGCT cis rs1997103 0.798 rs12154964 chr7:55414041 G/A cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1218582 0.772 rs4845682 chr1:154877105 T/C cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT trans rs28595532 0.623 rs11932674 chr4:119306807 A/C cg26518628 chr1:97050305 NA -0.51 -7.54 -0.56 8.58e-12 Cannabis dependence symptom count; TGCT cis rs42648 0.567 rs12669304 chr7:89891040 T/C cg25739043 chr7:89950458 NA -0.63 -6.12 -0.48 1.16e-8 Homocysteine levels; TGCT cis rs1371867 0.846 rs1660348 chr8:101315248 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs61867294 0.553 rs10884072 chr10:106732440 A/T cg08000847 chr10:105880925 C10orf78 0.48 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs2224391 0.534 rs2753229 chr6:5246633 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs7567389 0.740 rs1604817 chr2:127999921 C/T cg09760422 chr2:128146352 NA -0.35 -4.49 -0.37 1.58e-5 Self-rated health; TGCT cis rs12762955 0.561 rs7075141 chr10:1091195 C/T cg26597838 chr10:835615 NA -0.41 -5.45 -0.44 2.63e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs7572733 0.555 rs6745726 chr2:198934080 A/G cg00792783 chr2:198669748 PLCL1 0.58 5.16 0.42 9.47e-7 Dermatomyositis; TGCT cis rs17376456 0.825 rs13182631 chr5:93115701 A/G cg21475434 chr5:93447410 FAM172A 0.63 4.92 0.4 2.72e-6 Diabetic retinopathy; TGCT cis rs2120019 1.000 rs2083731 chr15:75368538 A/C cg11632617 chr15:75315747 PPCDC -0.34 -4.82 -0.4 4.18e-6 Blood trace element (Zn levels); TGCT cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg24675658 chr1:53192096 ZYG11B 0.86 11.3 0.71 8.54e-21 Monocyte count; TGCT cis rs1949733 0.701 rs1880024 chr4:8454639 A/G cg11789530 chr4:8429930 ACOX3 0.54 5.09 0.42 1.28e-6 Response to antineoplastic agents; TGCT cis rs1552244 0.882 rs56332224 chr3:10037321 G/A cg00149659 chr3:10157352 C3orf10 0.78 4.99 0.41 2.04e-6 Alzheimer's disease; TGCT cis rs1696756 0.638 rs1290396 chr17:77830767 C/T cg00646381 chr17:77835854 NA 0.44 6.6 0.51 1.06e-9 Glucocorticoid-induced osteonecrosis (age 10 years and older); TGCT trans rs66573146 1.000 rs28729690 chr4:6962061 C/T cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT trans rs208520 1.000 rs208535 chr6:66962286 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.88 -8.21 -0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs13102973 0.932 rs13149380 chr4:135866539 A/C cg14419869 chr4:135874104 NA 0.24 4.46 0.37 1.83e-5 Subjective well-being; TGCT cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg10263370 chr3:44754102 ZNF502 -0.45 -5.35 -0.43 4.08e-7 Depressive symptoms; TGCT cis rs6748734 0.948 rs9973334 chr2:241838142 A/G cg04034577 chr2:241836375 C2orf54 -0.42 -6.33 -0.49 4.04e-9 Urinary metabolites; TGCT cis rs7226408 0.857 rs72885256 chr18:34430466 A/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9549260 0.755 rs12585277 chr13:41224813 C/T cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs36051895 0.623 rs1830610 chr9:5260079 C/T cg02405213 chr9:5042618 JAK2 -0.71 -9.72 -0.66 6.17e-17 Pediatric autoimmune diseases; TGCT cis rs45509595 0.841 rs200485 chr6:27775697 G/C cg10876282 chr6:28092338 ZSCAN16 0.76 4.53 0.38 1.38e-5 Breast cancer; TGCT cis rs4689388 0.926 rs4688986 chr4:6285797 C/A cg00701064 chr4:6280414 WFS1 0.46 6.31 0.49 4.55e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg04632378 chr13:21900426 NA 0.43 5.04 0.41 1.6e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs4727027 0.704 rs13221837 chr7:148903597 C/T cg23583168 chr7:148888333 NA -0.78 -10.61 -0.69 4.12e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs11098499 0.954 rs4309825 chr4:120314881 C/T cg09307838 chr4:120376055 NA -0.66 -6.46 -0.5 2.11e-9 Corneal astigmatism; TGCT cis rs2760061 0.505 rs708109 chr1:228190657 C/T cg18477163 chr1:228402036 OBSCN 0.35 7.09 0.54 8.81e-11 Diastolic blood pressure; TGCT cis rs11779988 0.629 rs7465361 chr8:17854155 T/C cg01800426 chr8:17659068 MTUS1 -0.57 -4.97 -0.41 2.14e-6 Breast cancer; TGCT cis rs986417 0.901 rs1955694 chr14:61020617 G/T cg27398547 chr14:60952738 C14orf39 1.29 10.37 0.68 1.57e-18 Gut microbiota (bacterial taxa); TGCT cis rs11577318 0.853 rs11247913 chr1:26648551 G/C cg04990556 chr1:26633338 UBXN11 -0.64 -5.56 -0.45 1.56e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs7614311 0.636 rs6802053 chr3:63999823 A/C cg22134162 chr3:63841271 THOC7 -0.37 -4.73 -0.39 5.91e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs2816062 0.813 rs2816044 chr1:18892826 A/G cg18795169 chr1:18902165 NA -0.58 -13.28 -0.77 1.36e-25 Urate levels in lean individuals; TGCT cis rs600231 0.708 rs1784100 chr11:65249227 T/C cg17120908 chr11:65337727 SSSCA1 -0.56 -5.23 -0.42 7.04e-7 Bone mineral density; TGCT cis rs2153535 0.601 rs969420 chr6:8451966 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs56104184 0.723 rs1058483 chr19:49407660 G/A cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs7017914 0.870 rs1353057 chr8:71922097 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs478304 0.654 rs10896034 chr11:65460783 T/A cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.8e-13 Acne (severe); TGCT cis rs1218582 0.744 rs6674853 chr1:154892753 G/C cg06418219 chr1:154948305 SHC1;CKS1B -0.64 -6.32 -0.49 4.33e-9 Prostate cancer; TGCT cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.24 0.43 6.6e-7 Height; TGCT cis rs4765905 0.522 rs2283291 chr12:2337460 G/A cg07807026 chr12:2041581 NA -0.25 -4.57 -0.38 1.17e-5 Schizophrenia; TGCT cis rs7843479 0.601 rs6557712 chr8:21826421 C/T cg17168535 chr8:21777572 XPO7 0.82 8.4 0.6 8.71e-14 Mean corpuscular volume; TGCT cis rs9486719 1.000 rs11153064 chr6:97021959 A/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs11690935 0.959 rs12692970 chr2:172594197 T/C cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.51 -0.75 9.78e-24 Schizophrenia; TGCT cis rs4689592 0.622 rs2276968 chr4:7070118 T/G cg26116260 chr4:7069785 GRPEL1 1.07 9.82 0.66 3.49e-17 Monocyte percentage of white cells; TGCT cis rs7731657 0.537 rs72801772 chr5:130341294 G/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs78456975 1.000 rs11891809 chr2:1566001 A/G cg01028140 chr2:1542097 TPO -0.33 -4.54 -0.38 1.29e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs346785 0.692 rs8072944 chr17:74291733 T/G cg09812376 chr17:74270190 QRICH2 -0.36 -5.33 -0.43 4.43e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs2349775 0.513 rs984505 chr7:8622589 C/A cg10443049 chr7:8481537 NXPH1 0.45 4.45 0.37 1.9e-5 Neuroticism; TGCT cis rs10464366 0.746 rs12674262 chr7:39141728 G/T cg15212455 chr7:39170539 POU6F2 0.27 5.9 0.47 3.28e-8 IgG glycosylation; TGCT cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg03806693 chr22:41940476 POLR3H -1.11 -11.64 -0.72 1.26e-21 Vitiligo; TGCT cis rs60843830 1.000 rs17713396 chr2:227201 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.89 0.53 2.52e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs17125944 0.505 rs2295827 chr14:53174981 C/T cg00686598 chr14:53173677 PSMC6 1.2 6.42 0.5 2.59e-9 Alzheimer's disease (late onset); TGCT cis rs1372520 0.532 rs2583972 chr4:90747411 T/G cg20003494 chr4:90757398 SNCA -0.6 -4.66 -0.39 7.93e-6 Neuroticism; TGCT cis rs854765 0.583 rs11656840 chr17:17837354 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs875971 0.660 rs79009421 chr7:66068509 G/C cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT trans rs7342694 0.965 rs7189462 chr16:81907867 T/G cg04928372 chr6:27720905 NA 0.7 6.7 0.52 6.54e-10 Coronary artery disease; TGCT cis rs4780401 0.609 rs55934118 chr16:11820003 G/C cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs9435341 0.965 rs61798468 chr1:107569316 T/G cg09367891 chr1:107599246 PRMT6 0.62 5.28 0.43 5.67e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg20637647 chr7:64974828 NA 0.98 5.18 0.42 8.86e-7 Diabetic kidney disease; TGCT cis rs17376456 0.825 rs6874766 chr5:93213807 C/G cg25358565 chr5:93447407 FAM172A -0.99 -8.12 -0.59 4.01e-13 Diabetic retinopathy; TGCT cis rs2120019 0.938 rs8030089 chr15:75290377 C/T cg17294928 chr15:75287854 SCAMP5 -0.78 -6.08 -0.48 1.4e-8 Blood trace element (Zn levels); TGCT cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg07424592 chr7:64974309 NA 1.26 8.11 0.59 4.17e-13 Diabetic kidney disease; TGCT cis rs1005277 0.579 rs11011461 chr10:38431427 G/A cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs295140 0.546 rs842830 chr2:201131124 C/T cg23649088 chr2:200775458 C2orf69 -0.29 -4.91 -0.4 2.75e-6 QT interval; TGCT cis rs4455778 0.659 rs10262746 chr7:49031298 G/T cg26309511 chr7:48887640 NA 0.44 5.22 0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs6088580 0.634 rs6059851 chr20:33047945 G/A cg06115741 chr20:33292138 TP53INP2 0.55 4.68 0.39 7.39e-6 Glomerular filtration rate (creatinine); TGCT cis rs8017423 0.647 rs10132599 chr14:90815342 C/T cg04374321 chr14:90722782 PSMC1 -0.54 -5.57 -0.45 1.51e-7 Mortality in heart failure; TGCT cis rs933688 1.000 rs1035476 chr5:90745976 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.97 8.15 0.59 3.38e-13 Smoking behavior; TGCT cis rs2439831 0.681 rs484846 chr15:43600803 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.63 0.51 9.35e-10 Lung cancer in ever smokers; TGCT trans rs208520 0.526 rs1385219 chr6:66754476 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.06 14.9 0.8 2.08e-29 Exhaled nitric oxide output; TGCT cis rs3733585 0.699 rs10001964 chr4:9959275 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.54 -0.56 8.83e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs17152411 1.000 rs10901843 chr10:126638020 A/G cg07906193 chr10:126599966 NA 0.42 5.29 0.43 5.32e-7 Height; TGCT cis rs1538970 0.847 rs1771550 chr1:45883565 C/T cg05343316 chr1:45956843 TESK2 -0.75 -6.08 -0.48 1.39e-8 Platelet count; TGCT cis rs6435161 0.959 rs72926966 chr2:203493293 C/A cg18429434 chr2:203499731 FAM117B -0.48 -4.52 -0.38 1.45e-5 Total cholesterol levels; TGCT trans rs916888 0.610 rs199446 chr17:44813169 G/A cg10053473 chr17:62856997 LRRC37A3 0.4 6.77 0.52 4.68e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1971136 1 rs1971136 chr2:25291539 C/T cg01884057 chr2:25150051 NA -0.39 -8.01 -0.58 7.24e-13 Breast cancer; TGCT cis rs9733 0.596 rs6692960 chr1:150695965 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs2677744 0.814 rs4932379 chr15:91488676 T/C cg23684204 chr15:91497937 RCCD1 0.34 5.25 0.43 6.37e-7 Attention deficit hyperactivity disorder; TGCT cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg20999797 chr1:1681921 NA 0.18 4.61 0.38 9.67e-6 Body mass index; TGCT cis rs3796352 0.881 rs35385050 chr3:52997945 C/A cg07884673 chr3:53033167 SFMBT1 0.63 5.74 0.46 6.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4819052 1.000 rs13052356 chr21:46663588 G/A cg06618935 chr21:46677482 NA -0.37 -5.04 -0.41 1.64e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg21016266 chr12:122356598 WDR66 0.5 7.11 0.54 7.97e-11 Mean corpuscular volume; TGCT cis rs9513593 1.000 rs2296044 chr13:100038825 T/C cg21788972 chr13:99853209 UBAC2 0.56 4.68 0.39 7.51e-6 Psoriasis; TGCT cis rs1857353 1.000 rs12410333 chr1:75895626 T/C cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs2013441 1.000 rs2189710 chr17:20078964 C/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs11792861 0.816 rs113624314 chr9:111689953 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.54 5.13 0.42 1.07e-6 Menarche (age at onset); TGCT cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.21 0.49 7.25e-9 Gut microbiome composition (summer); TGCT cis rs611744 0.608 rs667742 chr8:109254003 T/C cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs7647973 0.925 rs4955423 chr3:49220448 G/A cg05785598 chr3:49045655 WDR6 0.38 4.68 0.39 7.48e-6 Menarche (age at onset); TGCT cis rs8180040 0.653 rs6808742 chr3:47051512 G/A cg27129171 chr3:47204927 SETD2 0.74 9.79 0.66 4.15e-17 Colorectal cancer; TGCT cis rs17030434 0.953 rs12639885 chr4:154700374 G/A cg14289246 chr4:154710475 SFRP2 -0.95 -7.52 -0.56 9.48e-12 Electrocardiographic conduction measures; TGCT cis rs593982 0.843 rs552312 chr11:65477349 C/T cg08755490 chr11:65554678 OVOL1 1.31 7.71 0.57 3.5e-12 Atopic dermatitis; TGCT cis rs896854 0.517 rs1011795 chr8:95951073 G/A cg13393036 chr8:95962371 TP53INP1 -0.49 -5.61 -0.45 1.26e-7 Type 2 diabetes; TGCT cis rs1577917 1.000 rs12205548 chr6:86759770 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.86e-7 Response to antipsychotic treatment; TGCT cis rs4699052 0.928 rs2866642 chr4:104213866 T/G cg16532752 chr4:104119610 CENPE -0.53 -4.8 -0.4 4.42e-6 Testicular germ cell tumor; TGCT cis rs6671200 0.607 rs6671408 chr1:95697091 T/C cg26537280 chr1:95699037 RWDD3 -0.51 -4.73 -0.39 6.03e-6 Stearic acid (18:0) levels; TGCT trans rs877282 1.000 rs112522746 chr10:772288 T/C cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs57590327 0.503 rs17019299 chr3:81851643 A/G cg07356753 chr3:81810745 GBE1 -0.67 -6.15 -0.48 9.91e-9 Extraversion; TGCT cis rs7267979 0.773 rs6132821 chr20:25226192 A/G cg16686733 chr20:25566563 NINL 0.52 4.9 0.4 2.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2239547 0.618 rs2071041 chr3:52864693 T/G cg11645453 chr3:52864694 ITIH4 0.37 6.32 0.49 4.19e-9 Schizophrenia; TGCT cis rs968451 0.865 rs2007418 chr22:39712394 T/C cg17798944 chr22:39715225 SNORD43;RPL3 0.84 8.45 0.6 6.74e-14 Primary biliary cholangitis; TGCT cis rs10514758 0.744 rs74657184 chr3:114821549 G/A cg05943254 chr3:114009756 NA -0.85 -5.06 -0.41 1.48e-6 Urate levels in obese individuals; TGCT cis rs763121 0.853 rs138709 chr22:39139216 C/G cg06022373 chr22:39101656 GTPBP1 0.73 7.11 0.54 8.14e-11 Menopause (age at onset); TGCT cis rs2721195 0.874 rs2721197 chr8:145727705 A/G cg15857475 chr8:145742913 RECQL4;LRRC14 0.89 9.55 0.65 1.6e-16 Age at first birth; TGCT cis rs42648 0.837 rs13239439 chr7:89924400 C/A cg25739043 chr7:89950458 NA -0.73 -7.32 -0.55 2.79e-11 Homocysteine levels; TGCT cis rs854765 0.505 rs4924832 chr17:17897739 A/G cg04398451 chr17:18023971 MYO15A -0.31 -4.84 -0.4 3.84e-6 Total body bone mineral density; TGCT cis rs854765 0.547 rs2955384 chr17:17939573 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 8.14 0.59 3.6e-13 Total body bone mineral density; TGCT trans rs1496653 0.602 rs34322396 chr3:23488499 T/C cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs2153535 0.580 rs1360054 chr6:8520377 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs875971 0.830 rs427973 chr7:65526648 C/A cg11764359 chr7:65958608 NA 0.53 4.65 0.38 8.53e-6 Aortic root size; TGCT cis rs7208859 0.673 rs2269916 chr17:29233763 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6964587 1.000 rs6956431 chr7:91750016 T/C cg22709100 chr7:91322751 NA 0.28 4.49 0.37 1.62e-5 Breast cancer; TGCT cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg14983838 chr19:29218262 NA 0.84 6.9 0.53 2.42e-10 Methadone dose in opioid dependence; TGCT cis rs838147 0.537 rs603985 chr19:49207257 T/C cg13540341 chr19:49222985 MAMSTR -0.37 -4.91 -0.4 2.84e-6 Dietary macronutrient intake; TGCT cis rs617219 0.698 rs10055956 chr5:78479678 G/A cg05890484 chr5:78407552 BHMT 0.38 5.23 0.42 7.13e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9916302 0.731 rs11868030 chr17:37650332 A/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs7614311 0.555 rs58676857 chr3:63903883 G/A cg22134162 chr3:63841271 THOC7 -0.37 -4.89 -0.4 3.01e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs1941023 0.584 rs2241921 chr11:60164302 C/T cg08716584 chr11:60157161 MS4A7 -0.34 -5.03 -0.41 1.66e-6 Congenital heart disease (maternal effect); TGCT cis rs61867294 0.578 rs7095209 chr10:106781929 A/G cg10601616 chr10:106400702 SORCS3 -0.61 -4.58 -0.38 1.12e-5 Schizophrenia; TGCT cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg27588902 chr6:42928151 GNMT -0.49 -5.93 -0.47 2.85e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7267979 0.933 rs6138571 chr20:25435388 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7662987 0.517 rs2602876 chr4:100039535 A/T cg12011299 chr4:100065546 ADH4 0.4 4.76 0.39 5.26e-6 Smoking initiation; TGCT cis rs208520 0.690 rs866452 chr6:66849936 A/T cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.33e-16 Exhaled nitric oxide output; TGCT cis rs17331151 0.505 rs35225119 chr3:52623465 A/T cg15956490 chr3:53032818 SFMBT1 0.75 5.94 0.47 2.74e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7216064 1.000 rs35243555 chr17:65876477 G/C cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg03806693 chr22:41940476 POLR3H -1.01 -11.18 -0.71 1.71e-20 Vitiligo; TGCT cis rs9914988 0.943 rs7211502 chr17:27163295 C/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7103648 0.838 rs11039244 chr11:47466442 G/A cg20307385 chr11:47447363 PSMC3 0.98 10.95 0.7 6.2e-20 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs2832191 0.967 rs2898160 chr21:30487496 A/G cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs6570726 0.537 rs1280279 chr6:145884048 G/T cg05347473 chr6:146136440 FBXO30 0.64 5.1 0.42 1.21e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs2018683 1.000 rs4719963 chr7:29011064 A/G cg19402173 chr7:128379420 CALU 0.72 7.02 0.53 1.25e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; TGCT cis rs114540395 0.858 rs17767748 chr10:103285900 A/G cg18276125 chr10:102749041 C10orf2 -0.42 -4.89 -0.4 3.04e-6 Schizophrenia; TGCT cis rs9486715 0.838 rs6928442 chr6:96870118 A/G cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs12413816 0.784 rs11258560 chr10:13770137 A/G cg16485048 chr10:13749193 FRMD4A 0.26 5.32 0.43 4.71e-7 Red cell distribution width; TGCT cis rs7917772 0.503 rs2031601 chr10:104308064 T/G cg05855489 chr10:104503620 C10orf26 -0.6 -5.25 -0.43 6.32e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.830 rs28416660 chr4:98899525 C/G cg17366294 chr4:99064904 C4orf37 0.67 6.83 0.52 3.3e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs910316 0.967 rs175432 chr14:75615246 C/G cg08847533 chr14:75593920 NEK9 -0.93 -9.75 -0.66 5.19e-17 Height; TGCT cis rs28735056 0.875 rs62103181 chr18:77625652 A/G cg20368463 chr18:77673604 PQLC1 0.4 4.89 0.4 3.09e-6 Schizophrenia; TGCT cis rs3784262 0.771 rs4775005 chr15:58208165 C/T cg12031962 chr15:58353849 ALDH1A2 0.56 7.98 0.58 8.5e-13 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6693567 0.526 rs3818978 chr1:150266338 T/A cg09579323 chr1:150459698 TARS2 -0.52 -4.7 -0.39 6.77e-6 Migraine; TGCT cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg05368731 chr17:41323189 NBR1 1.1 11.12 0.71 2.38e-20 Menopause (age at onset); TGCT cis rs12908161 0.853 rs12912342 chr15:85248216 T/C cg17173187 chr15:85201210 NMB 0.42 5.0 0.41 1.92e-6 Schizophrenia; TGCT cis rs12497850 0.931 rs1134591 chr3:48972892 C/T cg18654377 chr3:49208889 KLHDC8B -0.46 -5.77 -0.46 6.1e-8 Parkinson's disease; TGCT cis rs6681544 0.544 rs2182601 chr1:82396801 C/T cg04226724 chr1:82268649 LPHN2 0.47 4.99 0.41 2.02e-6 Metabolite levels (X-11787); TGCT cis rs2832191 0.716 rs1543652 chr21:30448000 G/C cg24692254 chr21:30365293 RNF160 0.98 11.33 0.71 7.51e-21 Dental caries; TGCT cis rs11671005 0.695 rs8106061 chr19:58917990 G/C cg03735888 chr19:58951602 ZNF132 0.79 6.69 0.52 6.81e-10 Mean platelet volume; TGCT cis rs35146811 0.735 rs858505 chr7:99819577 G/A cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs4654899 0.680 rs11805006 chr1:21249603 C/T cg01072550 chr1:21505969 NA -0.53 -8.74 -0.62 1.39e-14 Superior frontal gyrus grey matter volume; TGCT cis rs7833790 1.000 rs7833384 chr8:82730915 T/C cg17211192 chr8:82754475 SNX16 -1.05 -8.95 -0.63 4.23e-15 Diastolic blood pressure; TGCT cis rs644799 0.965 rs10831425 chr11:95500628 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.85 0.62 7.27e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs694739 0.628 rs645078 chr11:64135298 A/C cg23796481 chr11:64053134 BAD;GPR137 0.65 6.82 0.52 3.49e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs1903068 0.719 rs1380068 chr4:56003707 C/G cg01777861 chr4:56023843 NA 0.52 5.79 0.46 5.56e-8 Endometriosis; TGCT trans rs17685 0.753 rs11982200 chr7:75714883 T/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.59 0.61 3.07e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs977747 0.872 rs12145836 chr1:47672289 A/T cg03885399 chr1:47691550 TAL1 -0.43 -5.42 -0.44 2.97e-7 Body mass index; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg10150615 chr22:24372951 LOC391322 0.77 6.51 0.5 1.7e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2456568 0.775 rs1607404 chr11:93660449 C/G cg26875233 chr11:93583750 C11orf90 -0.47 -5.86 -0.47 3.87e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3806843 0.547 rs183679 chr5:140271017 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.42 5.05 0.41 1.52e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9419702 0.538 rs9419628 chr10:133539299 A/C cg04492858 chr10:133558786 NA 0.57 6.03 0.48 1.71e-8 Survival in rectal cancer; TGCT cis rs7568458 0.811 rs1446668 chr2:85764960 G/T cg02493740 chr2:85810744 VAMP5 -0.29 -5.33 -0.43 4.51e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs8072100 0.817 rs9912101 chr17:45547078 A/G cg08085267 chr17:45401833 C17orf57 -0.45 -5.09 -0.42 1.31e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs889312 0.500 rs33328 chr5:56143419 T/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs6733011 0.531 rs13004923 chr2:99497561 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.5 -4.9 -0.4 2.99e-6 Bipolar disorder; TGCT cis rs7833790 0.750 rs10108955 chr8:82690644 C/T cg06027949 chr8:82754900 SNX16 -0.67 -4.47 -0.37 1.75e-5 Diastolic blood pressure; TGCT cis rs9796 0.870 rs11854472 chr15:41357687 G/A cg18705301 chr15:41695430 NDUFAF1 -0.43 -5.62 -0.45 1.22e-7 Menopause (age at onset); TGCT cis rs2692947 0.740 rs11695514 chr2:96548068 C/T cg13655245 chr2:97463316 CNNM4 0.16 4.6 0.38 1.02e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4951018 0.853 rs1573104 chr1:205636907 A/C cg26354017 chr1:205819088 PM20D1 -0.39 -4.59 -0.38 1.08e-5 Prostate-specific antigen levels; TGCT cis rs11711311 1.000 rs12497716 chr3:113453258 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.73 -6.83 -0.52 3.45e-10 IgG glycosylation; TGCT cis rs7412746 0.587 rs11204722 chr1:150730184 A/C cg04414720 chr1:150670196 GOLPH3L -0.4 -5.16 -0.42 9.42e-7 Melanoma; TGCT cis rs1865760 0.566 rs9295688 chr6:26084217 G/A cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs8051149 0.688 rs3815559 chr16:87871366 G/C cg01412419 chr16:87856264 NA 0.49 5.79 0.46 5.38e-8 Blood metabolite levels; TGCT cis rs7666738 0.830 rs34412187 chr4:99010454 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs7618501 0.633 rs55751738 chr3:49972101 A/G cg21659725 chr3:3221576 CRBN 0.76 9.03 0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.882 rs13062917 chr3:10017032 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs478304 0.619 rs10896028 chr11:65432187 A/T cg27068330 chr11:65405492 SIPA1 -1.0 -10.85 -0.7 1.09e-19 Acne (severe); TGCT cis rs1008375 0.931 rs10939733 chr4:17570658 T/C cg10189774 chr4:17578691 LAP3 0.67 5.87 0.47 3.77e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1552244 1.000 rs68067759 chr3:10150535 T/C cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs711245 0.545 rs848617 chr2:36811298 G/C cg10546459 chr2:36825355 FEZ2 0.55 4.71 0.39 6.61e-6 Height; TGCT cis rs6088580 0.609 rs945674 chr20:32964247 G/C cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT trans rs877282 0.685 rs56234340 chr10:781339 A/G cg22713356 chr15:30763199 NA 1.0 8.75 0.62 1.27e-14 Uric acid levels; TGCT cis rs7588654 1.000 rs72613757 chr2:219968869 G/A cg06736663 chr2:219754761 WNT10A -0.48 -4.79 -0.39 4.72e-6 Height; TGCT cis rs3849570 0.695 rs6792696 chr3:81874009 G/A cg07356753 chr3:81810745 GBE1 -0.6 -5.31 -0.43 4.92e-7 Waist circumference;Body mass index; TGCT cis rs2820315 0.867 rs2819351 chr1:201885157 C/T cg12730843 chr1:201915899 LMOD1 -0.27 -4.86 -0.4 3.46e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs7819412 0.669 rs7823349 chr8:10998630 G/T cg03192020 chr8:11204681 TDH -0.52 -4.5 -0.37 1.53e-5 Triglycerides; TGCT cis rs7267979 0.966 rs2261794 chr20:25263062 T/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs910316 0.789 rs4899552 chr14:75667921 C/A cg08847533 chr14:75593920 NEK9 -0.84 -8.25 -0.6 1.92e-13 Height; TGCT cis rs765787 0.530 rs2899378 chr15:45537584 C/T cg24006582 chr15:45444508 DUOX1 0.24 5.28 0.43 5.64e-7 Uric acid levels; TGCT cis rs4595586 0.967 rs11169807 chr12:39244161 A/G cg10518543 chr12:38710700 ALG10B 0.48 4.81 0.4 4.25e-6 Morning vs. evening chronotype; TGCT cis rs7572733 0.534 rs734037 chr2:198749269 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs7192750 0.562 rs152838 chr16:72105702 C/T cg14768367 chr16:72042858 DHODH 0.89 4.65 0.39 8.32e-6 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2120019 1.000 rs2083731 chr15:75368538 A/C cg09165964 chr15:75287851 SCAMP5 -1.09 -8.86 -0.62 7.08e-15 Blood trace element (Zn levels); TGCT cis rs7666738 0.830 rs6852015 chr4:99054373 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs904251 0.523 rs1776455 chr6:37482923 A/T cg01843034 chr6:37503916 NA -0.51 -6.91 -0.53 2.24e-10 Cognitive performance; TGCT cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg23758822 chr17:41437982 NA 0.75 7.03 0.53 1.22e-10 Menopause (age at onset); TGCT cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6831352 0.918 rs29001199 chr4:100053891 A/G cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs7568458 0.684 rs60012532 chr2:85752474 A/C cg17127132 chr2:85788382 GGCX 0.51 4.72 0.39 6.29e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs72634258 0.520 rs12078018 chr1:7857309 G/A cg26816564 chr1:7831052 VAMP3 0.87 6.44 0.5 2.34e-9 Inflammatory bowel disease; TGCT cis rs78707713 0.560 rs35060419 chr10:71229539 A/G cg12610070 chr10:71211762 TSPAN15 -0.62 -7.31 -0.55 2.83e-11 Venous thromboembolism; TGCT cis rs6061231 0.837 rs6061235 chr20:60978524 C/G cg24112000 chr20:60950667 NA -0.39 -5.06 -0.41 1.48e-6 Colorectal cancer; TGCT cis rs4727027 0.870 rs11524138 chr7:148799125 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.68 0.39 7.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7267979 1.000 rs2482930 chr20:25334115 G/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs926938 0.527 rs6680112 chr1:115548915 G/C cg12756093 chr1:115239321 AMPD1 0.35 5.11 0.42 1.18e-6 Autism; TGCT cis rs13191362 1.000 rs34177053 chr6:163007772 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs473651 0.904 rs501333 chr2:239336045 G/A cg08773314 chr2:239334832 ASB1 0.45 7.5 0.56 1.07e-11 Multiple system atrophy; TGCT cis rs2067615 0.579 rs9651957 chr12:107170128 A/G cg15890332 chr12:107067104 RFX4 0.28 5.83 0.46 4.48e-8 Heart rate; TGCT trans rs1005277 0.522 rs289650 chr10:37975505 G/T cg17830980 chr10:43048298 ZNF37B -0.66 -7.51 -0.56 1.03e-11 Extrinsic epigenetic age acceleration; TGCT cis rs12048904 0.595 rs10493937 chr1:101342650 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.65 -7.03 -0.53 1.21e-10 Multiple sclerosis; TGCT cis rs11971779 0.651 rs74368518 chr7:139004327 A/G cg07862535 chr7:139043722 LUC7L2 0.71 5.82 0.46 4.83e-8 Diisocyanate-induced asthma; TGCT cis rs1018836 0.886 rs12545351 chr8:91636668 C/T cg16814680 chr8:91681699 NA -0.8 -8.6 -0.61 2.89e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6901004 0.803 rs11153272 chr6:111479539 C/T cg15721981 chr6:111408429 SLC16A10 -0.51 -4.57 -0.38 1.16e-5 Blood metabolite levels; TGCT cis rs2880765 0.835 rs7164106 chr15:86032590 T/C cg13263323 chr15:86062960 AKAP13 -0.22 -4.79 -0.4 4.68e-6 Coronary artery disease; TGCT cis rs7772486 0.875 rs2224120 chr6:146343280 A/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.56 -0.38 1.23e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs739496 0.793 rs73199895 chr12:111866087 G/A cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT trans rs1005277 0.529 rs1780125 chr10:38531376 A/G cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs748404 0.660 rs690012 chr15:43719755 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs9549367 0.569 rs3024719 chr13:113814225 G/A cg00898013 chr13:113819073 PROZ -0.55 -6.53 -0.51 1.52e-9 Platelet distribution width; TGCT cis rs28595532 0.920 rs55869953 chr4:119751893 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7614311 0.639 rs73119035 chr3:63993966 A/G cg22134162 chr3:63841271 THOC7 -0.49 -6.44 -0.5 2.41e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg12310025 chr6:25882481 NA 0.9 9.22 0.64 9.6e-16 Blood metabolite levels; TGCT cis rs704 0.628 rs8081240 chr17:26722728 C/T cg10342447 chr17:26645325 TMEM97 -0.47 -4.69 -0.39 7.22e-6 Osteoprotegerin levels; TGCT cis rs858239 0.932 rs1624451 chr7:23262435 A/T cg05602783 chr7:23145260 KLHL7 0.61 4.9 0.4 2.98e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs3008870 0.755 rs1925410 chr1:67365230 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.75 -7.86 -0.58 1.63e-12 Lymphocyte percentage of white cells; TGCT cis rs9905704 0.624 rs11652761 chr17:56986095 C/T cg12560992 chr17:57184187 TRIM37 0.58 4.93 0.4 2.57e-6 Testicular germ cell tumor; TGCT cis rs798766 1.000 rs4865463 chr4:1742400 T/C cg05874882 chr4:1763078 NA -0.33 -4.56 -0.38 1.2e-5 Bladder cancer;Urinary bladder cancer; TGCT cis rs9926296 0.585 rs8045232 chr16:89857548 A/G cg21285383 chr16:89894308 SPIRE2 0.45 7.16 0.54 6.39e-11 Vitiligo; TGCT cis rs7940866 0.834 rs10894298 chr11:130840571 C/A cg12179176 chr11:130786555 SNX19 0.62 5.95 0.47 2.57e-8 Schizophrenia; TGCT cis rs7103648 1.000 rs7103648 chr11:47461783 A/G cg20307385 chr11:47447363 PSMC3 1.07 13.03 0.76 5.56e-25 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs769267 0.965 rs8103496 chr19:19386015 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs9611565 0.729 rs202654 chr22:41841034 G/A cg06481639 chr22:41940642 POLR3H 0.59 5.12 0.42 1.12e-6 Vitiligo; TGCT cis rs13064411 0.696 rs35860985 chr3:113209828 C/T cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7465272 0.530 rs10103161 chr8:143738571 A/G cg10596483 chr8:143751796 JRK 0.56 5.58 0.45 1.46e-7 Bipolar disorder and schizophrenia; TGCT cis rs10114408 0.959 rs2095779 chr9:96648831 T/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6570726 0.935 rs419850 chr6:145827281 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1580019 0.563 rs34319173 chr7:32585904 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.2 15.19 0.81 4.33e-30 Cognitive ability; TGCT cis rs2296887 0.585 rs10786663 chr10:104064548 A/G cg26089160 chr10:104170217 PSD -0.56 -5.66 -0.45 9.94e-8 Parkinson's disease; TGCT cis rs2463822 1.000 rs2513074 chr11:62100880 A/C cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT trans rs6951245 0.529 rs10262070 chr7:1141738 C/T cg13565492 chr6:43139072 SRF -0.77 -7.34 -0.55 2.43e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9972944 0.622 rs1895033 chr17:63777493 A/C cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs12042938 0.507 rs2570408 chr1:231732934 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.55 -5.4 -0.44 3.2e-7 Neuranatomic and neurocognitive phenotypes; TGCT cis rs3008870 1.000 rs2009319 chr1:67481070 G/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.91 0.73 2.83e-22 Lymphocyte percentage of white cells; TGCT cis rs1163251 0.902 rs839605 chr1:120217524 C/A cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs7661264 chr4:98961574 G/A cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs477895 0.713 rs3802933 chr11:63988102 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.82 6.82 0.52 3.53e-10 Mean platelet volume; TGCT cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg00149659 chr3:10157352 C3orf10 0.97 5.09 0.42 1.28e-6 Alzheimer's disease; TGCT cis rs2882667 0.931 rs10044736 chr5:138320809 A/G cg04439458 chr5:138467593 SIL1 0.29 4.62 0.38 9.64e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs2469997 1.000 rs2957356 chr8:120373995 T/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs911555 0.713 rs10162425 chr14:103931621 C/T cg12935359 chr14:103987150 CKB -0.32 -4.47 -0.37 1.73e-5 Intelligence (multi-trait analysis); TGCT cis rs2652822 0.686 rs4774476 chr15:63407390 A/G cg12855773 chr15:63363890 TPM1 0.16 4.66 0.39 7.92e-6 Metabolic traits; TGCT cis rs2235642 0.750 rs2755185 chr16:1645827 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.28 -4.88 -0.4 3.24e-6 Coronary artery disease; TGCT cis rs6570726 0.764 rs4896821 chr6:145896181 G/A cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12971120 0.947 rs34676212 chr18:72170006 A/G cg25817165 chr18:72167213 CNDP2 -0.3 -5.6 -0.45 1.33e-7 Refractive error; TGCT cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg09323728 chr8:95962352 TP53INP1 -0.49 -6.32 -0.49 4.32e-9 Type 2 diabetes; TGCT cis rs4742903 0.967 rs6479215 chr9:106885243 A/G cg21169611 chr9:106856078 SMC2 -0.56 -5.37 -0.43 3.73e-7 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs4888262 0.716 rs6564157 chr16:74710254 T/C cg01733217 chr16:74700730 RFWD3 0.92 10.74 0.69 1.97e-19 Testicular germ cell tumor; TGCT cis rs2228479 0.764 rs11641201 chr16:89983276 T/C cg06558623 chr16:89946397 TCF25 0.47 6.27 0.49 5.52e-9 Skin colour saturation; TGCT cis rs9733 0.519 rs7511673 chr1:150707636 A/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs1541995 0.824 rs17506333 chr15:96253243 C/T cg00882281 chr15:96346592 NA -0.29 -4.77 -0.39 5.12e-6 Photic sneeze reflex; TGCT cis rs7208859 0.673 rs9896095 chr17:29187497 A/G cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs7618501 0.966 rs2246832 chr3:49881134 A/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.7e-25 Intelligence (multi-trait analysis); TGCT cis rs7113874 0.589 rs9705253 chr11:8596483 A/T cg14521421 chr11:8862019 ST5 0.28 4.44 0.37 1.96e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7208859 0.623 rs9895785 chr17:29107708 C/T cg13385521 chr17:29058706 SUZ12P -0.86 -5.16 -0.42 9.48e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7267979 0.586 rs6050429 chr20:25183058 G/A cg03522245 chr20:25566470 NINL 0.5 5.27 0.43 5.88e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs922182 0.783 rs12438519 chr15:64311345 C/T cg02919090 chr15:64263738 DAPK2 0.25 4.54 0.38 1.29e-5 Blood protein levels; TGCT cis rs617219 0.671 rs12189188 chr5:78552312 C/T cg23987322 chr5:78407566 BHMT 0.36 4.66 0.39 8.06e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs28595532 0.920 rs114210107 chr4:119734491 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs6089584 0.546 rs6061978 chr20:60615604 C/T cg06108461 chr20:60628389 TAF4 -0.43 -5.5 -0.44 2.06e-7 Body mass index; TGCT trans rs7618501 1.000 rs57648519 chr3:49813169 C/A cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs4699591 chr4:98974171 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.554 rs7638846 chr3:10048601 A/G cg00149659 chr3:10157352 C3orf10 0.73 5.21 0.42 7.77e-7 Alzheimer's disease; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs9611565 1.000 rs1109151 chr22:41752944 A/G cg03806693 chr22:41940476 POLR3H -0.98 -10.5 -0.69 7.62e-19 Vitiligo; TGCT trans rs7618501 0.521 rs7615206 chr3:49937505 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.36 0.6 1.06e-13 Intelligence (multi-trait analysis); TGCT trans rs877282 0.898 rs11253348 chr10:765852 C/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.44 0.56 1.46e-11 Prudent dietary pattern; TGCT cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg13683864 chr3:40499215 RPL14 -1.13 -12.23 -0.74 4.85e-23 Renal cell carcinoma; TGCT cis rs7666738 0.830 rs34916200 chr4:98851593 C/T cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.897 rs2776308 chr21:40715175 A/G cg11890956 chr21:40555474 PSMG1 0.99 9.11 0.63 1.78e-15 Cognitive function; TGCT cis rs909674 0.865 rs5757683 chr22:39850174 G/A cg05872129 chr22:39784769 NA -0.97 -9.64 -0.65 9.53e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg10150615 chr22:24372951 LOC391322 -0.98 -11.96 -0.73 2.1e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9868809 0.505 rs35064573 chr3:48740280 C/A cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs10504229 0.683 rs6999351 chr8:58127227 C/T cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs1372520 0.873 rs2736989 chr4:90776257 T/C cg15133208 chr4:90757351 SNCA -0.5 -5.9 -0.47 3.18e-8 Neuroticism; TGCT cis rs7017914 0.869 rs11987511 chr8:71645871 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs4851254 0.660 rs13430705 chr2:100690616 G/A cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs2839186 0.900 rs2839196 chr21:47708037 G/A cg25737836 chr21:47705150 C21orf57;MCM3AP -0.18 -4.45 -0.37 1.92e-5 Testicular germ cell tumor; TGCT cis rs3096299 0.606 rs4785573 chr16:89565403 A/G cg06640241 chr16:89574553 SPG7 0.52 4.67 0.39 7.7e-6 Multiple myeloma (IgH translocation); TGCT cis rs7524258 0.835 rs7543228 chr1:7306538 G/C cg04342483 chr1:7259290 CAMTA1 -0.31 -4.43 -0.37 2.01e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg17554472 chr22:41940697 POLR3H 0.43 4.47 0.37 1.73e-5 Vitiligo; TGCT cis rs7267979 0.789 rs6083841 chr20:25384564 C/T cg21995068 chr20:25989032 LOC100134868 0.43 5.17 0.42 9.2e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs79839061 0.520 rs2279187 chr4:875529 C/T cg07828340 chr4:882639 GAK 0.36 4.71 0.39 6.4e-6 Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs1814175 0.645 rs11040671 chr11:49958776 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs10883723 0.810 rs3818470 chr10:104263675 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4689388 0.610 rs4328980 chr4:6281756 A/G cg14416269 chr4:6271139 WFS1 0.39 4.97 0.41 2.18e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7192750 0.586 rs1834035 chr16:71972271 C/G cg06353428 chr16:71660113 MARVELD3 0.77 6.82 0.52 3.61e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg12437481 chr16:420112 MRPL28 -0.5 -5.03 -0.41 1.65e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.71 -7.06 -0.54 1.07e-10 Prudent dietary pattern; TGCT cis rs7586879 0.681 rs6756609 chr2:25121125 C/A cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs9527 0.590 rs4917992 chr10:104786313 G/A cg04362960 chr10:104952993 NT5C2 0.58 4.65 0.39 8.5e-6 Arsenic metabolism; TGCT cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg13683864 chr3:40499215 RPL14 -1.1 -11.83 -0.73 4.49e-22 Renal cell carcinoma; TGCT cis rs11167764 1.000 rs7730511 chr5:141480418 T/C cg23435118 chr5:141488016 NDFIP1 -0.29 -4.89 -0.4 3.06e-6 Crohn's disease; TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg18402987 chr7:1209562 NA 0.37 4.73 0.39 6.09e-6 Longevity;Endometriosis; TGCT trans rs210152 0.588 rs449978 chr6:33496060 G/A cg08795360 chr21:41033440 B3GALT5 -0.44 -6.68 -0.51 7.12e-10 Schizophrenia; TGCT cis rs10972341 1.000 rs7046814 chr9:35142258 A/G cg00812861 chr9:35114699 KIAA1539 0.33 4.92 0.4 2.73e-6 Weight; TGCT cis rs10464366 0.510 rs62442212 chr7:39146896 A/C cg15212455 chr7:39170539 POU6F2 0.25 5.85 0.46 4.18e-8 IgG glycosylation; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg12419862 chr22:24373484 LOC391322 -0.79 -6.49 -0.5 1.89e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs3751972 0.748 rs1034895 chr17:26225558 C/G cg02948944 chr17:26242737 NA -0.48 -6.82 -0.52 3.52e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs72615157 0.595 rs112241539 chr7:99847237 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.65 -5.2 -0.42 8.01e-7 Lung function (FEV1/FVC); TGCT cis rs4919669 0.777 rs11191375 chr10:104464657 T/C cg05855489 chr10:104503620 C10orf26 0.73 4.45 0.37 1.91e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs3087591 1.000 rs7216033 chr17:29574642 A/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.42 -0.55 1.64e-11 Hip circumference; TGCT cis rs7666738 0.791 rs62318641 chr4:98816964 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.25 0.43 6.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs56104184 0.775 rs73061697 chr19:49400000 C/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs4576506 0.536 rs13292862 chr9:31506598 T/C cg11445191 chr5:140227765 PCDHA6;PCDHA2;PCDHA1;PCDHA7;PCDHA5;PCDHA9;PCDHA3;PCDHA4;PCDHA8 0.98 6.69 0.51 6.76e-10 Psychosis and Alzheimer's disease; TGCT cis rs2204008 0.744 rs11182316 chr12:38499552 G/A cg13010199 chr12:38710504 ALG10B 0.64 5.15 0.42 9.97e-7 Bladder cancer; TGCT cis rs10782582 0.609 rs78748984 chr1:76340467 G/A cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs7819412 0.594 rs7460507 chr8:10969075 C/T cg03192020 chr8:11204681 TDH -0.56 -5.41 -0.44 3.06e-7 Triglycerides; TGCT cis rs2204008 0.599 rs2320526 chr12:38220405 T/A cg26384229 chr12:38710491 ALG10B 0.83 7.45 0.56 1.35e-11 Bladder cancer; TGCT cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT trans rs916888 0.773 rs199533 chr17:44828931 G/A cg07870213 chr5:140052090 DND1 0.64 7.57 0.56 7.47e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg09323728 chr8:95962352 TP53INP1 -0.54 -6.92 -0.53 2.17e-10 Type 2 diabetes; TGCT cis rs3540 0.597 rs1978151 chr15:91037300 C/T cg22089800 chr15:90895588 ZNF774 0.76 7.77 0.57 2.62e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs11190604 1.000 rs11190556 chr10:102209223 G/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9926296 0.535 rs36022917 chr16:89893238 A/G cg03388025 chr16:89894329 SPIRE2 0.35 5.28 0.43 5.66e-7 Vitiligo; TGCT trans rs916888 0.610 rs142167 chr17:44795234 C/T cg22433210 chr17:43662623 NA -0.95 -8.12 -0.59 3.95e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs68170813 0.652 rs6957186 chr7:107200592 T/C cg02696742 chr7:106810147 HBP1 -0.59 -4.71 -0.39 6.61e-6 Coronary artery disease; TGCT cis rs478304 0.903 rs61895677 chr11:65549415 T/C cg17480646 chr11:65405466 SIPA1 0.41 5.03 0.41 1.7e-6 Acne (severe); TGCT cis rs11931598 0.783 rs28661210 chr4:7050956 C/A cg02503808 chr4:7069936 GRPEL1 0.58 5.35 0.43 4.14e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs4819052 0.807 rs7283915 chr21:46671288 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs769267 0.930 rs6511038 chr19:19607564 A/C cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs9653442 1.000 rs7580200 chr2:100811903 G/T cg22139774 chr2:100720529 AFF3 0.43 7.46 0.56 1.31e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11167764 1.000 rs7722567 chr5:141483178 C/T cg08523384 chr5:141488047 NDFIP1 -0.26 -5.21 -0.42 7.52e-7 Crohn's disease; TGCT cis rs60843830 1.000 rs7595075 chr2:264019 C/A cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.93 0.53 2.07e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs8070740 0.898 rs4239056 chr17:5324406 A/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.77 0.39 5.1e-6 Menopause (age at onset); TGCT cis rs10186029 0.680 rs10179508 chr2:213978526 C/T cg08319019 chr2:214017104 IKZF2 -0.64 -5.82 -0.46 4.64e-8 Systemic sclerosis; TGCT cis rs6750795 0.502 rs11685196 chr2:232381298 A/G cg07301105 chr2:232379665 C2orf52 0.4 5.48 0.44 2.29e-7 Height; TGCT cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs2153535 0.580 rs1928184 chr6:8532108 T/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs1552244 0.554 rs2272118 chr3:10049287 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg18876405 chr7:65276391 NA -0.35 -5.49 -0.44 2.13e-7 Aortic root size; TGCT cis rs68170813 0.599 rs12532849 chr7:106959226 A/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs2456568 0.503 rs11020603 chr11:93667439 A/G cg26875233 chr11:93583750 C11orf90 0.44 5.27 0.43 5.78e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs78366141 0.649 rs78959409 chr4:89659712 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.16 5.16 0.42 9.33e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs2288073 0.965 rs10192600 chr2:24396680 A/G cg02683114 chr2:24398427 C2orf84 -0.25 -5.61 -0.45 1.26e-7 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs981844 1.000 rs72731674 chr4:154667447 C/A cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs6938 0.618 rs11633472 chr15:75184084 T/G cg10253484 chr15:75165896 SCAMP2 -0.6 -5.5 -0.44 2.06e-7 Breast cancer; TGCT cis rs8020441 1.000 rs72681672 chr14:51169600 C/T cg04730355 chr14:51134070 SAV1 0.73 5.86 0.47 3.91e-8 Cognitive performance; TGCT cis rs2354432 0.607 rs6703847 chr1:146669444 G/A cg25205988 chr1:146714368 CHD1L 1.34 6.29 0.49 4.92e-9 Mitochondrial DNA levels; TGCT cis rs137699 1.000 rs5757632 chr22:39756097 A/C cg11247378 chr22:39784982 NA -0.47 -5.2 -0.42 8.13e-7 IgG glycosylation; TGCT cis rs8051431 0.840 rs3929023 chr16:72011040 A/G cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs1843834 0.898 rs11887386 chr2:225526975 T/G cg22455342 chr2:225449267 CUL3 0.74 7.25 0.55 3.9e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs425277 0.606 rs3128295 chr1:2068480 C/T cg03732007 chr1:2071316 PRKCZ -0.28 -5.99 -0.47 2.12e-8 Height; TGCT cis rs262150 0.579 rs73167299 chr7:158784367 C/T cg01219135 chr7:158766336 NA -0.47 -4.92 -0.4 2.72e-6 Facial morphology (factor 20); TGCT cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg03806693 chr22:41940476 POLR3H -1.15 -13.16 -0.76 2.69e-25 Vitiligo; TGCT cis rs67311347 0.956 rs11714871 chr3:40428938 T/G cg13683864 chr3:40499215 RPL14 -1.05 -11.13 -0.71 2.2e-20 Renal cell carcinoma; TGCT cis rs6540559 0.546 rs75308488 chr1:210030639 T/C cg12034118 chr1:209979487 IRF6 0.64 4.48 0.37 1.7e-5 Cleft lip with or without cleft palate; TGCT cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT trans rs6089829 0.925 rs4809270 chr20:61676709 C/A cg13615516 chr5:77269221 NA 0.73 8.42 0.6 7.74e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs9457247 1.000 rs448060 chr6:167382622 A/G cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs4409675 0.548 rs1000432 chr1:28225119 T/C cg23691781 chr1:28212827 C1orf38 0.25 5.26 0.43 6.19e-7 Corneal astigmatism; TGCT cis rs10779751 1.000 rs7525957 chr1:11318236 C/T cg08854313 chr1:11322531 MTOR 0.99 10.58 0.69 4.78e-19 Body mass index; TGCT cis rs992157 0.796 rs55680399 chr2:219160621 T/C cg00012203 chr2:219082015 ARPC2 0.78 7.72 0.57 3.38e-12 Colorectal cancer; TGCT cis rs9788721 0.836 rs17405217 chr15:78731149 C/T cg18825076 chr15:78729989 IREB2 -0.35 -5.23 -0.43 7.03e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs7772486 0.754 rs6570718 chr6:146088443 T/G cg05347473 chr6:146136440 FBXO30 -0.53 -5.01 -0.41 1.84e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2180341 0.960 rs7766802 chr6:127709871 T/G cg27446573 chr6:127587934 RNF146 1.16 10.47 0.68 9.13e-19 Breast cancer; TGCT cis rs6088580 0.634 rs6059880 chr20:33088669 G/A cg06115741 chr20:33292138 TP53INP2 0.53 4.66 0.39 7.96e-6 Glomerular filtration rate (creatinine); TGCT cis rs9972944 0.756 rs4594282 chr17:63762930 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.24 -0.43 6.6e-7 Total body bone mineral density; TGCT cis rs8180040 0.900 rs10865946 chr3:47425060 T/G cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs9325144 0.723 rs11169482 chr12:39164327 A/T cg26384229 chr12:38710491 ALG10B 0.61 5.89 0.47 3.44e-8 Morning vs. evening chronotype; TGCT cis rs2070433 0.539 rs1008548 chr21:47959692 G/A cg12379764 chr21:47803548 PCNT 0.53 5.29 0.43 5.36e-7 Lymphocyte counts; TGCT cis rs1008375 0.966 rs28441502 chr4:17598384 G/A cg18681998 chr4:17616180 MED28 0.94 9.66 0.66 8.59e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6088580 0.634 rs6059779 chr20:32950325 C/T cg08999081 chr20:33150536 PIGU -0.27 -5.33 -0.43 4.46e-7 Glomerular filtration rate (creatinine); TGCT cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg18402987 chr7:1209562 NA 0.74 6.19 0.49 7.92e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4969178 0.622 rs4129767 chr17:76403984 G/A cg05887092 chr17:76393375 PGS1 0.22 4.64 0.38 8.75e-6 HDL cholesterol levels; TGCT cis rs2243480 1.000 rs73142122 chr7:65311298 C/A cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs3091242 0.933 rs9645452 chr1:25668326 C/T cg10117171 chr1:25599238 RHD 0.35 5.57 0.45 1.5e-7 Erythrocyte sedimentation rate; TGCT cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg13395646 chr4:1353034 KIAA1530 -0.4 -5.25 -0.43 6.39e-7 Obesity-related traits; TGCT trans rs1908814 0.541 rs7824267 chr8:11794279 G/T cg15556689 chr8:8085844 FLJ10661 0.76 7.3 0.55 3.04e-11 Neuroticism; TGCT cis rs295140 0.732 rs1367858 chr2:201160771 C/T cg04283868 chr2:201171347 SPATS2L 0.53 4.89 0.4 3.05e-6 QT interval; TGCT cis rs546131 0.890 rs485845 chr11:34830389 G/T cg11058730 chr11:34937778 PDHX;APIP -0.59 -5.16 -0.42 9.4e-7 Lung disease severity in cystic fibrosis; TGCT cis rs9467773 1.000 rs1321481 chr6:26538210 A/T cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg06753367 chr22:24256600 NA -0.24 -4.53 -0.38 1.36e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4555082 1.000 rs7146683 chr14:105759385 A/G cg10792982 chr14:105748885 BRF1 0.22 4.58 0.38 1.13e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs9467773 1.000 rs1321479 chr6:26501897 C/T cg26531700 chr6:26746687 NA -0.48 -4.82 -0.4 4.07e-6 Intelligence (multi-trait analysis); TGCT cis rs7010267 0.544 rs6984287 chr8:120054122 C/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.62 0.38 9.52e-6 Total body bone mineral density (age 45-60); TGCT cis rs4862750 0.872 rs10027252 chr4:187873462 T/G cg03452623 chr4:187889614 NA -0.35 -5.17 -0.42 9.06e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4788570 0.667 rs8053186 chr16:71790166 G/A cg06353428 chr16:71660113 MARVELD3 1.53 12.17 0.74 6.57e-23 Intelligence (multi-trait analysis); TGCT cis rs7226408 0.857 rs117376812 chr18:34549886 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1670533 0.872 rs6854793 chr4:1055768 T/C cg20887711 chr4:1340912 KIAA1530 0.69 5.48 0.44 2.32e-7 Recombination rate (females); TGCT cis rs10744422 1.000 rs1587856 chr12:123342229 A/G cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg01802117 chr1:53393560 SCP2 -0.45 -5.73 -0.46 7.03e-8 Monocyte count; TGCT cis rs6952808 0.692 rs10950473 chr7:1999453 G/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.25 -0.49 6.04e-9 Bipolar disorder and schizophrenia; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg12419862 chr22:24373484 LOC391322 -0.78 -8.06 -0.59 5.58e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6558530 0.730 rs7014327 chr8:1724052 C/T cg09410841 chr8:1729607 CLN8 0.86 10.13 0.67 6e-18 Systolic blood pressure; TGCT cis rs9303401 0.614 rs34678056 chr17:57177549 G/A cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs7412746 0.658 rs12090215 chr1:150893660 C/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs6430585 0.528 rs6750549 chr2:136707480 A/G cg07169764 chr2:136633963 MCM6 1.26 12.74 0.75 2.79e-24 Corneal structure; TGCT cis rs7666738 0.546 rs10461174 chr4:98698293 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.76 0.46 6.27e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3741404 0.672 rs4980524 chr11:63959259 A/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 8.19 0.59 2.68e-13 Platelet count; TGCT cis rs12908161 1.000 rs35316992 chr15:85248133 A/G cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs10751667 1.000 rs12798036 chr11:947585 T/C cg06064525 chr11:970664 AP2A2 -0.33 -6.59 -0.51 1.12e-9 Alzheimer's disease (late onset); TGCT cis rs7659604 0.605 rs2071486 chr4:122740162 C/T cg19748678 chr4:122722346 EXOSC9 0.81 8.3 0.6 1.46e-13 Type 2 diabetes; TGCT cis rs877529 0.625 rs139390 chr22:39532853 A/G cg18708252 chr22:39545030 CBX7 -0.38 -5.61 -0.45 1.28e-7 Multiple myeloma; TGCT cis rs7954584 0.626 rs12809676 chr12:122442381 C/A cg21171335 chr12:122356390 WDR66 0.7 6.84 0.52 3.28e-10 Mean corpuscular volume; TGCT cis rs8077889 0.672 rs4793028 chr17:41857212 T/C cg26893861 chr17:41843967 DUSP3 1.14 20.46 0.88 1.46e-41 Triglycerides; TGCT cis rs11252926 0.537 rs6560836 chr10:444997 C/T cg18196295 chr10:418757 DIP2C 0.3 4.92 0.4 2.69e-6 Psychosis in Alzheimer's disease; TGCT cis rs1008375 0.618 rs13129002 chr4:17567513 A/G cg10189774 chr4:17578691 LAP3 0.57 4.9 0.4 2.9e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs899997 1.000 rs7182993 chr15:79045014 G/A cg04896959 chr15:78267971 NA 0.35 5.07 0.41 1.4e-6 Coronary artery disease or large artery stroke; TGCT cis rs17331151 0.505 rs71299613 chr3:52698805 G/A cg24616795 chr3:53032891 SFMBT1 0.58 4.85 0.4 3.59e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2836974 0.899 rs2836957 chr21:40623134 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.65 0.65 9.11e-17 Cognitive function; TGCT cis rs2859741 0.967 rs535876 chr1:37484052 C/G cg09363841 chr1:37513479 NA -0.19 -4.46 -0.37 1.84e-5 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs17826219 0.636 rs12946563 chr17:29103166 C/G cg13385521 chr17:29058706 SUZ12P 0.8 4.71 0.39 6.51e-6 Body mass index; TGCT cis rs1005277 0.579 rs1780138 chr10:38501654 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6424115 0.830 rs2501425 chr1:24199339 A/C cg15997130 chr1:24165203 NA 0.86 9.44 0.65 2.86e-16 Immature fraction of reticulocytes; TGCT cis rs4631830 0.863 rs3123078 chr10:51524971 A/G cg10326726 chr10:51549505 MSMB 0.24 4.85 0.4 3.68e-6 Prostate-specific antigen levels; TGCT cis rs3771570 1.000 rs73002111 chr2:242277833 C/T cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs8177253 1.000 rs8177248 chr3:133479626 C/T cg08439880 chr3:133502540 NA -0.28 -4.98 -0.41 2.09e-6 Iron status biomarkers; TGCT cis rs9733 0.596 rs72702580 chr1:150691285 A/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs12579753 0.719 rs12369450 chr12:82266940 A/G cg07988820 chr12:82153109 PPFIA2 -0.42 -4.44 -0.37 1.97e-5 Resting heart rate; TGCT cis rs6752107 0.967 rs12162308 chr2:234172188 C/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.65 0.39 8.35e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1797081 0.811 rs1797076 chr10:16853076 A/G cg14835575 chr10:16859367 RSU1 0.4 5.02 0.41 1.72e-6 Platelet distribution width; TGCT cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs9985766 1.000 rs10003178 chr4:150998544 A/G cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs2288073 0.965 rs13387930 chr2:24414400 A/G cg05570707 chr2:24270316 C2orf44 -0.5 -4.47 -0.37 1.72e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs17068510 0.630 rs17068551 chr8:3873763 T/C cg25338036 chr8:3047536 CSMD1 -0.46 -4.88 -0.4 3.19e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9486719 0.895 rs12190520 chr6:96928620 A/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.77 -0.62 1.18e-14 Migraine;Coronary artery disease; TGCT cis rs2115630 0.967 rs7171167 chr15:85239123 A/T cg12501888 chr15:85177176 SCAND2 -0.51 -4.84 -0.4 3.85e-6 P wave terminal force; TGCT cis rs737008 0.922 rs11074957 chr16:11378151 G/A cg00044050 chr16:11439710 C16orf75 -0.71 -7.27 -0.55 3.49e-11 Obesity-related traits; TGCT cis rs6076065 0.748 rs6048781 chr20:23380027 T/C cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.25 4.54 0.38 1.32e-5 Schizophrenia; TGCT cis rs11031096 0.711 rs17283923 chr11:4173841 C/T cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2204008 0.522 rs12370263 chr12:38113311 A/G cg13010199 chr12:38710504 ALG10B 0.6 4.79 0.4 4.7e-6 Bladder cancer; TGCT cis rs9467773 0.511 rs11755443 chr6:26891603 T/C cg02458000 chr6:26745757 NA 0.66 5.88 0.47 3.59e-8 Intelligence (multi-trait analysis); TGCT cis rs10986311 0.775 rs3758206 chr9:127151871 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs7647973 0.961 rs4955430 chr3:49378088 G/A cg06212747 chr3:49208901 KLHDC8B 0.59 4.72 0.39 6.22e-6 Menarche (age at onset); TGCT cis rs1008375 1.000 rs2315556 chr4:17670861 T/C cg10189774 chr4:17578691 LAP3 0.53 4.99 0.41 2e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1050631 0.960 rs1789512 chr18:33694542 C/T cg25426722 chr18:33708991 SLC39A6;ELP2 -0.54 -5.29 -0.43 5.4e-7 Esophageal squamous cell cancer (length of survival); TGCT cis rs936229 1.000 rs4886615 chr15:75131661 A/G cg10253484 chr15:75165896 SCAMP2 -0.78 -6.44 -0.5 2.4e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs908922 0.887 rs1538084 chr1:152496012 A/C cg20991723 chr1:152506922 NA 0.42 5.32 0.43 4.6e-7 Hair morphology; TGCT cis rs801193 0.935 rs2659899 chr7:66186721 A/G cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs317865 0.867 rs73234625 chr4:16166206 G/A cg04764131 chr4:16228633 TAPT1;FLJ39653 0.8 5.08 0.42 1.34e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs1488864 0.655 rs1844188 chr11:6346572 A/G cg12755421 chr11:6342214 PRKCDBP -0.56 -4.45 -0.37 1.89e-5 Smooth-surface caries; TGCT trans rs17685 0.725 rs7807647 chr7:75628669 G/A cg19862616 chr7:65841803 NCRNA00174 -0.5 -8.68 -0.61 1.94e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs769267 0.929 rs34538000 chr19:19481379 G/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.7 -5.93 -0.47 2.75e-8 Tonsillectomy; TGCT cis rs3749237 0.595 rs11130199 chr3:49538799 T/C cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs782590 0.967 rs58003472 chr2:55797507 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.88 0.53 2.6e-10 Metabolic syndrome; TGCT cis rs1865760 0.532 rs9295687 chr6:26082710 T/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs433598 0.765 rs234288 chr16:20660327 A/G cg08248577 chr16:19727447 IQCK;C16orf88 0.22 5.03 0.41 1.64e-6 Schizophrenia; TGCT cis rs11711311 0.955 rs12630791 chr3:113387717 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.74 6.52 0.51 1.58e-9 IgG glycosylation; TGCT cis rs4819052 0.765 rs2838868 chr21:46714641 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.61 -4.76 -0.39 5.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6495122 0.532 rs2470890 chr15:75047426 C/T cg13906792 chr15:75199810 C15orf17 -0.22 -4.71 -0.39 6.64e-6 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs11722228 1.000 rs6823877 chr4:9921931 T/C cg11266682 chr4:10021025 SLC2A9 -0.52 -5.86 -0.47 3.98e-8 Gout;Urate levels;Serum uric acid levels; TGCT cis rs2404602 0.655 rs3829489 chr15:77223256 A/C cg26408565 chr15:76604113 ETFA -0.37 -4.63 -0.38 9.04e-6 Blood metabolite levels; TGCT cis rs2842992 0.789 rs2295901 chr6:160201295 C/A cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs950169 1.000 rs79318564 chr15:84786150 G/A cg11189052 chr15:85197271 WDR73 0.72 6.09 0.48 1.32e-8 Schizophrenia; TGCT cis rs9527 0.590 rs12355120 chr10:104852166 T/G cg04362960 chr10:104952993 NT5C2 0.68 5.78 0.46 5.57e-8 Arsenic metabolism; TGCT cis rs1552244 1.000 rs113153120 chr3:10156398 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.94 -0.53 1.89e-10 Alzheimer's disease; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg08859206 chr1:53392774 SCP2 -0.41 -6.12 -0.48 1.11e-8 Monocyte count; TGCT cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7246657 0.722 rs13744 chr19:38077912 C/T cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs17473412 0.677 rs11749673 chr5:122834239 C/G cg15125798 chr5:122621645 NA 0.61 5.31 0.43 4.92e-7 Total body bone mineral density; TGCT cis rs2235642 0.750 rs1894649 chr16:1657284 C/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.27 -4.53 -0.38 1.37e-5 Coronary artery disease; TGCT cis rs3733585 0.699 rs60045583 chr4:9971950 G/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.51e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11105298 0.891 rs10777162 chr12:89830523 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.65 -4.61 -0.38 9.91e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs3733585 0.563 rs881971 chr4:9930962 A/G cg00071950 chr4:10020882 SLC2A9 -0.51 -5.76 -0.46 6.2e-8 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs1864729 1.000 rs1835743 chr8:98282643 T/C cg08679828 chr8:102218111 ZNF706 -0.98 -6.67 -0.51 7.76e-10 Estradiol plasma levels (breast cancer); TGCT cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg07424592 chr7:64974309 NA 1.27 7.08 0.54 9.24e-11 Diabetic kidney disease; TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg03310518 chr7:30954522 AQP1 0.31 6.88 0.53 2.56e-10 Phosphorus levels; TGCT cis rs2034088 0.619 rs4968170 chr17:404712 T/C cg04370829 chr17:406249 NA -0.36 -5.26 -0.43 6.01e-7 Hip circumference adjusted for BMI; TGCT cis rs1218582 0.772 rs4845682 chr1:154877105 T/C cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs10465746 0.967 rs6703382 chr1:84435700 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.23 0.49 6.49e-9 Obesity-related traits; TGCT cis rs8067545 0.750 rs3862152 chr17:19959693 C/T cg13482628 chr17:19912719 NA 0.53 4.59 0.38 1.07e-5 Schizophrenia; TGCT cis rs10986311 0.779 rs10818942 chr9:127077395 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -5.04 -0.41 1.58e-6 Vitiligo; TGCT cis rs9341808 0.667 rs7746917 chr6:80931503 T/C cg08355045 chr6:80787529 NA 0.3 4.99 0.41 1.99e-6 Sitting height ratio; TGCT cis rs7772486 0.875 rs854145 chr6:146349650 C/T cg05347473 chr6:146136440 FBXO30 0.57 5.42 0.44 2.92e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2859741 1.000 rs1773575 chr1:37505129 T/C cg09363841 chr1:37513479 NA -0.19 -4.49 -0.37 1.63e-5 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs4727027 0.865 rs13236754 chr7:148845773 G/A cg23583168 chr7:148888333 NA -0.76 -9.69 -0.66 7.27e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs8084125 1.000 rs72978665 chr18:74953641 A/G cg15443732 chr18:74961078 GALR1 0.49 4.82 0.4 4.18e-6 Obesity-related traits; TGCT cis rs9457247 0.565 rs2239823 chr6:167512131 T/C cg07741184 chr6:167504864 NA 0.28 5.6 0.45 1.33e-7 Crohn's disease; TGCT cis rs1971762 0.730 rs7963016 chr12:54072819 T/A cg22546318 chr12:54070378 ATP5G2 -0.31 -4.48 -0.37 1.68e-5 Height; TGCT cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs912057 1.000 rs912056 chr6:6736197 A/T cg06612196 chr6:6737390 NA 0.38 4.77 0.39 5.06e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs6912958 0.781 rs4707376 chr6:88270947 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg14820908 chr5:178986412 RUFY1 0.59 6.22 0.49 6.87e-9 Lung cancer; TGCT cis rs425277 0.916 rs414777 chr1:2101687 G/A cg24578937 chr1:2090814 PRKCZ 0.31 7.58 0.56 6.92e-12 Height; TGCT cis rs7824557 0.564 rs2736304 chr8:11236964 C/T cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.92e-9 Retinal vascular caliber; TGCT cis rs28735056 0.846 rs12958903 chr18:77628996 A/G cg20368463 chr18:77673604 PQLC1 0.4 4.89 0.4 3.09e-6 Schizophrenia; TGCT cis rs7772486 0.686 rs9497396 chr6:146014963 C/A cg23711669 chr6:146136114 FBXO30 -0.85 -9.45 -0.65 2.66e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs8064299 0.597 rs4789098 chr17:72781292 C/G cg25054828 chr17:72772726 NAT9;TMEM104 0.88 10.27 0.68 2.76e-18 Monocyte count; TGCT cis rs13102973 0.931 rs6822196 chr4:135855582 T/A cg14419869 chr4:135874104 NA 0.23 4.58 0.38 1.12e-5 Subjective well-being; TGCT cis rs6545883 0.862 rs778141 chr2:61682178 A/G cg15711740 chr2:61764176 XPO1 -0.53 -4.79 -0.4 4.59e-6 Tuberculosis; TGCT cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg23758822 chr17:41437982 NA 0.71 6.77 0.52 4.56e-10 Menopause (age at onset); TGCT cis rs7829975 0.688 rs7827182 chr8:8380471 C/G cg06636001 chr8:8085503 FLJ10661 0.78 7.57 0.56 7.46e-12 Mood instability; TGCT cis rs2657888 1.000 rs17540509 chr12:56943840 T/C cg23002907 chr12:56915593 RBMS2 -0.44 -5.82 -0.46 4.69e-8 Adiponectin levels; TGCT cis rs1163251 0.902 rs514491 chr1:120216743 C/T cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs7572733 0.555 rs11889006 chr2:198928647 A/G cg00792783 chr2:198669748 PLCL1 0.57 4.98 0.41 2.1e-6 Dermatomyositis; TGCT cis rs28595532 0.920 rs114916728 chr4:119776886 G/A cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs7208859 0.673 rs9895815 chr17:29138033 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1568889 1.000 rs12802830 chr11:28321196 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.84 8.47 0.61 5.84e-14 Bipolar disorder; TGCT cis rs6912958 1.000 rs6912958 chr6:88133315 G/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.42 -5.31 -0.43 4.88e-7 Monocyte percentage of white cells; TGCT cis rs554111 0.634 rs10799673 chr1:21274671 T/G cg01072550 chr1:21505969 NA 0.35 5.36 0.43 3.88e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs4372836 0.504 rs13030945 chr2:29087799 C/A cg09522027 chr2:28974177 PPP1CB -0.57 -5.63 -0.45 1.14e-7 Body mass index; TGCT cis rs2242116 0.727 rs4683298 chr3:46966387 C/G cg23352942 chr3:46931381 PTH1R -0.32 -4.8 -0.4 4.49e-6 Birth weight; TGCT trans rs1864729 0.748 rs2567770 chr8:98296720 C/T cg08679828 chr8:102218111 ZNF706 -1.03 -6.8 -0.52 3.9e-10 Estradiol plasma levels (breast cancer); TGCT cis rs72717009 0.825 rs7515174 chr1:161476949 C/G cg23840854 chr1:161414152 NA -0.98 -5.86 -0.47 3.95e-8 Rheumatoid arthritis; TGCT cis rs6988636 1.000 rs57902736 chr8:124189893 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs11671005 0.735 rs11666716 chr19:58920952 A/G cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT cis rs3733585 0.673 rs4311316 chr4:9955971 A/C cg11266682 chr4:10021025 SLC2A9 0.58 7.7 0.57 3.72e-12 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs1814175 0.715 rs10839409 chr11:49884647 G/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs9913156 0.517 rs12452404 chr17:4587355 C/T cg00122941 chr17:4613640 ARRB2 -0.73 -6.88 -0.53 2.68e-10 Lymphocyte counts; TGCT cis rs1215050 0.755 rs6843393 chr4:98822619 C/G cg05340658 chr4:99064831 C4orf37 0.45 5.78 0.46 5.8e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs36051895 0.659 rs11999076 chr9:5037694 C/T cg02405213 chr9:5042618 JAK2 -0.83 -11.98 -0.73 1.89e-22 Pediatric autoimmune diseases; TGCT cis rs9611519 0.603 rs4821999 chr22:41470001 A/G cg03806693 chr22:41940476 POLR3H -0.51 -4.57 -0.38 1.14e-5 Neuroticism; TGCT cis rs7267979 1.000 rs6050629 chr20:25430680 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2742417 1.000 rs2673033 chr3:45756350 C/G cg04837898 chr3:45731254 SACM1L -0.56 -5.98 -0.47 2.24e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6684514 1.000 rs12027103 chr1:156244856 G/A cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg22963979 chr7:1858916 MAD1L1 -0.39 -6.18 -0.49 8.65e-9 Bipolar disorder and schizophrenia; TGCT cis rs62283056 0.512 rs10028875 chr4:6283460 C/T cg14416269 chr4:6271139 WFS1 0.39 4.91 0.4 2.85e-6 Cisplatin-induced ototoxicity; TGCT cis rs1568889 1.000 rs66702115 chr11:28181703 T/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.75 0.62 1.26e-14 Bipolar disorder; TGCT cis rs2842992 0.915 rs2842985 chr6:160085434 C/T cg11366901 chr6:160182831 ACAT2 0.96 6.28 0.49 5.21e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs6866344 0.697 rs6873150 chr5:178125704 G/A cg10224037 chr5:178157518 ZNF354A 0.94 8.06 0.59 5.44e-13 Neutrophil percentage of white cells; TGCT cis rs7584330 0.554 rs113271883 chr2:238425594 A/G cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs6690583 0.623 rs12042845 chr1:85429801 A/G cg20280350 chr1:85513789 MCOLN3 -0.68 -4.49 -0.37 1.6e-5 Serum sulfate level; TGCT cis rs1941023 0.584 rs4938941 chr11:60173360 C/T cg08716584 chr11:60157161 MS4A7 0.31 4.77 0.39 5.13e-6 Congenital heart disease (maternal effect); TGCT cis rs9467773 1.000 rs1884946 chr6:26545308 C/G cg09904177 chr6:26538194 HMGN4 0.65 6.48 0.5 1.95e-9 Intelligence (multi-trait analysis); TGCT cis rs6893300 0.524 rs12374446 chr5:179131143 A/G cg14593053 chr5:179126677 CANX 0.47 5.24 0.43 6.56e-7 Resting heart rate; TGCT cis rs7681440 0.835 rs6532198 chr4:90798870 C/T cg14346243 chr4:90757452 SNCA -0.5 -4.75 -0.39 5.46e-6 Dementia with Lewy bodies; TGCT cis rs611744 0.967 rs686630 chr8:109233239 G/C cg21045802 chr8:109455806 TTC35 0.52 4.71 0.39 6.5e-6 Dupuytren's disease; TGCT cis rs7772486 0.712 rs6570726 chr6:146159460 T/C cg23711669 chr6:146136114 FBXO30 0.78 7.51 0.56 1.02e-11 Lobe attachment (rater-scored or self-reported); TGCT trans rs10435719 0.902 rs12681142 chr8:11802601 T/C cg15556689 chr8:8085844 FLJ10661 0.76 7.24 0.55 4.06e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs1008375 1.000 rs1860596 chr4:17660082 C/T cg18681998 chr4:17616180 MED28 1.01 11.83 0.73 4.51e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6940638 0.688 rs7744759 chr6:27119826 G/A cg26531700 chr6:26746687 NA -0.52 -4.51 -0.38 1.5e-5 Intelligence (multi-trait analysis); TGCT cis rs4689592 0.503 rs56099074 chr4:7071259 A/G cg26116260 chr4:7069785 GRPEL1 -0.97 -7.78 -0.57 2.39e-12 Monocyte percentage of white cells; TGCT cis rs10464366 0.519 rs6974609 chr7:39219149 C/T cg18850127 chr7:39170497 POU6F2 0.31 6.2 0.49 7.75e-9 IgG glycosylation; TGCT cis rs17221829 0.627 rs7130892 chr11:89386606 T/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs478304 0.651 rs12225620 chr11:65505448 T/C cg17480646 chr11:65405466 SIPA1 -0.57 -6.95 -0.53 1.84e-10 Acne (severe); TGCT cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.79e-7 Menopause (age at onset); TGCT cis rs595982 0.559 rs17206714 chr19:49362001 T/A cg21252483 chr19:49399788 TULP2 -0.42 -6.43 -0.5 2.44e-9 Red cell distribution width; TGCT cis rs992157 0.710 rs56364928 chr2:219059058 G/A cg00012203 chr2:219082015 ARPC2 0.83 10.59 0.69 4.61e-19 Colorectal cancer; TGCT cis rs7296418 0.885 rs1716184 chr12:123637509 G/C cg00376283 chr12:123451042 ABCB9 0.84 7.66 0.57 4.68e-12 Platelet count; TGCT cis rs2228479 0.867 rs57940434 chr16:89975496 G/A cg06558623 chr16:89946397 TCF25 0.53 6.48 0.5 1.99e-9 Skin colour saturation; TGCT cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg06238570 chr21:40685208 BRWD1 -0.8 -9.1 -0.63 1.91e-15 Cognitive function; TGCT cis rs9467711 0.606 rs34273322 chr6:26415409 T/A cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg05064044 chr6:292385 DUSP22 -0.69 -7.17 -0.54 5.94e-11 Menopause (age at onset); TGCT cis rs950169 0.579 rs62027818 chr15:84661145 T/C cg11189052 chr15:85197271 WDR73 0.65 5.06 0.41 1.45e-6 Schizophrenia; TGCT cis rs12477438 0.798 rs9308816 chr2:99637230 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.79 -0.46 5.44e-8 Chronic sinus infection; TGCT cis rs644799 1.000 rs487609 chr11:95588102 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.63 0.61 2.51e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2239815 0.515 rs5762849 chr22:29238086 G/A cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs901683 0.702 rs78034568 chr10:46149580 G/C cg09623279 chr10:45395734 NA -0.49 -5.33 -0.43 4.55e-7 Red blood cell traits;Mean corpuscular volume; TGCT cis rs2180341 0.960 rs7766802 chr6:127709871 T/G cg24812749 chr6:127587940 RNF146 0.98 7.53 0.56 9.29e-12 Breast cancer; TGCT cis rs4720575 1.000 rs4724535 chr7:47100396 G/A cg00036614 chr7:47093842 NA -0.21 -5.28 -0.43 5.69e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs6988636 0.710 rs73339621 chr8:124138936 C/T cg27053337 chr8:124217698 FAM83A 0.77 5.55 0.45 1.65e-7 Urinary uromodulin levels; TGCT cis rs17221829 0.699 rs78403327 chr11:89384225 C/T cg02982614 chr11:89391479 FOLH1B -0.27 -4.66 -0.39 7.89e-6 Anxiety in major depressive disorder; TGCT cis rs62185668 0.693 rs6077966 chr20:10919740 A/G cg17778165 chr20:10414372 MKKS -0.58 -4.53 -0.38 1.35e-5 Urinary bladder cancer; TGCT cis rs6430585 0.591 rs309118 chr2:136746224 G/C cg07169764 chr2:136633963 MCM6 1.21 11.71 0.72 8.7e-22 Corneal structure; TGCT cis rs1887596 0.705 rs1590954 chr13:27200239 A/G cg01312412 chr13:27282625 NA 0.3 5.31 0.43 4.89e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs763121 0.853 rs138712 chr22:39141600 C/T cg06022373 chr22:39101656 GTPBP1 0.69 6.49 0.5 1.88e-9 Menopause (age at onset); TGCT cis rs1372520 0.684 rs2583968 chr4:90745395 C/G cg01966878 chr4:90757139 SNCA -0.3 -4.69 -0.39 7.05e-6 Neuroticism; TGCT cis rs10782582 0.609 rs79835994 chr1:76287508 G/T cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs875971 0.660 rs10272357 chr7:66063074 G/A cg18876405 chr7:65276391 NA -0.37 -5.66 -0.45 1e-7 Aortic root size; TGCT cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.94 7.39 0.55 1.89e-11 Platelet count; TGCT cis rs875971 0.862 rs1875057 chr7:65731855 A/G cg11764359 chr7:65958608 NA -0.54 -4.86 -0.4 3.45e-6 Aortic root size; TGCT cis rs1008375 0.902 rs7654332 chr4:17691778 A/T cg18681998 chr4:17616180 MED28 0.76 7.28 0.55 3.42e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3733585 0.673 rs4292333 chr4:9953871 G/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1971762 0.561 rs4759288 chr12:54084006 T/A cg16917193 chr12:54089295 NA 1.39 17.84 0.85 4.9e-36 Height; TGCT cis rs453301 0.686 rs11785819 chr8:8870378 T/G cg06636001 chr8:8085503 FLJ10661 -0.68 -5.63 -0.45 1.13e-7 Joint mobility (Beighton score); TGCT trans rs8073060 0.544 rs8071584 chr17:33999435 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7677751 0.806 rs17084051 chr4:55087581 C/A cg17187183 chr4:55093834 PDGFRA 0.54 7.13 0.54 7.45e-11 Corneal astigmatism; TGCT trans rs931812 1.000 rs931812 chr8:101919321 A/G cg20993868 chr7:22813445 NA -0.35 -7.72 -0.57 3.35e-12 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs2730245 0.527 rs2527194 chr7:158732959 G/A cg11984989 chr7:158649758 WDR60 -1.01 -7.85 -0.58 1.65e-12 Height; TGCT cis rs6089584 1.000 rs3787424 chr20:60559219 G/A cg16423285 chr20:60520624 NA -0.52 -5.45 -0.44 2.6e-7 Body mass index; TGCT cis rs8180040 0.966 rs11130137 chr3:47578838 C/T cg27129171 chr3:47204927 SETD2 0.62 7.22 0.54 4.69e-11 Colorectal cancer; TGCT cis rs929596 0.785 rs6747843 chr2:234664354 G/A cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.34 -5.49 -0.44 2.13e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs881375 0.967 rs1014529 chr9:123684943 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.42 4.63 0.38 9.27e-6 Rheumatoid arthritis; TGCT cis rs910316 1.000 rs2300601 chr14:75639571 A/G cg08847533 chr14:75593920 NEK9 0.91 10.09 0.67 7.72e-18 Height; TGCT cis rs501916 0.833 rs3809486 chr15:48051549 G/T cg16110827 chr15:48056943 SEMA6D -0.17 -4.68 -0.39 7.32e-6 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs6495122 0.644 rs62029217 chr15:75261899 C/T cg09165964 chr15:75287851 SCAMP5 0.51 4.65 0.39 8.33e-6 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs769267 0.965 rs2023882 chr19:19405405 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs4372836 1.000 rs2169751 chr2:28966758 G/C cg09522027 chr2:28974177 PPP1CB -0.59 -5.15 -0.42 1e-6 Body mass index; TGCT trans rs1973993 0.691 rs4000303 chr1:96913765 A/G cg10631902 chr5:14652156 NA 0.39 10.65 0.69 3.3e-19 Weight; TGCT cis rs10193935 0.901 rs222486 chr2:42649664 C/T cg27598129 chr2:42591480 NA -0.32 -4.65 -0.39 8.33e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2228479 0.541 rs12918575 chr16:89811151 A/G cg27121462 chr16:89883253 FANCA 0.77 4.61 0.38 9.93e-6 Skin colour saturation; TGCT cis rs1971762 0.527 rs6580958 chr12:54073483 A/G cg16917193 chr12:54089295 NA 1.31 16.3 0.83 1.29e-32 Height; TGCT cis rs1635 0.655 rs16893975 chr6:28302278 C/T cg15743358 chr6:28303923 ZNF323 1.24 6.25 0.49 5.93e-9 Schizophrenia; TGCT cis rs5769707 0.521 rs74351010 chr22:50036820 G/A cg03598726 chr22:50246859 ZBED4 -0.45 -4.49 -0.37 1.63e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs644799 0.544 rs1150360 chr11:95512060 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.57 6.21 0.49 7.25e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9814567 0.727 rs4437193 chr3:134352344 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -5.92 -0.47 2.97e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs938554 0.513 rs1014290 chr4:10001861 G/A cg00071950 chr4:10020882 SLC2A9 0.58 5.44 0.44 2.67e-7 Blood metabolite levels; TGCT cis rs2769264 0.505 rs4246526 chr1:151403916 G/T cg18801370 chr1:151430492 POGZ 0.62 5.62 0.45 1.19e-7 Blood trace element (Cu levels); TGCT cis rs4478858 0.735 rs34960310 chr1:31816197 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT trans rs561341 1.000 rs55978022 chr17:30275937 T/C cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs8180040 0.603 rs9854790 chr3:47101306 T/G cg27129171 chr3:47204927 SETD2 0.71 8.55 0.61 3.9e-14 Colorectal cancer; TGCT cis rs7191439 0.522 rs745326 chr16:88755245 C/G cg27087555 chr16:88793112 FAM38A -0.44 -4.57 -0.38 1.17e-5 Plateletcrit; TGCT cis rs6987853 0.966 rs2974359 chr8:42434194 T/C cg20539142 chr8:42623718 CHRNA6 -0.2 -4.84 -0.4 3.76e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs1008375 1.000 rs6449323 chr4:17683916 A/T cg18681998 chr4:17616180 MED28 0.86 8.97 0.63 3.76e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 0.932 rs6138588 chr20:25487523 C/T cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs68170813 0.559 rs7809508 chr7:107004119 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.73 -0.46 7.19e-8 Coronary artery disease; TGCT cis rs526231 0.578 rs17154825 chr5:102246069 T/C cg23492399 chr5:102201601 PAM -0.51 -4.49 -0.37 1.62e-5 Primary biliary cholangitis; TGCT cis rs2404602 0.692 rs2117369 chr15:76748861 A/T cg26408565 chr15:76604113 ETFA -0.4 -5.26 -0.43 6.23e-7 Blood metabolite levels; TGCT cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs6598955 0.671 rs55791848 chr1:26582711 G/A cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs6598955 0.670 rs10794525 chr1:26537193 C/A cg04990556 chr1:26633338 UBXN11 -0.89 -11.24 -0.71 1.2e-20 Obesity-related traits; TGCT cis rs523522 0.962 rs55848094 chr12:120966659 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs73058052 0.597 rs10404887 chr19:50096421 C/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.65 5.22 0.42 7.33e-7 Fibrinogen levels; TGCT cis rs6490294 0.799 rs11066082 chr12:112351348 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs1005277 0.579 rs9299760 chr10:38377920 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -7.9 -0.58 1.31e-12 Extrinsic epigenetic age acceleration; TGCT cis rs1008375 0.932 rs6857678 chr4:17696964 A/T cg18681998 chr4:17616180 MED28 0.78 7.33 0.55 2.6e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7020830 0.867 rs56098516 chr9:37362220 A/G cg14294708 chr9:37120828 ZCCHC7 1.15 15.73 0.82 2.55e-31 Schizophrenia; TGCT cis rs10465746 0.780 rs1952065 chr1:84464205 T/C cg10977910 chr1:84465055 TTLL7 0.67 6.54 0.51 1.47e-9 Obesity-related traits; TGCT cis rs35146811 0.695 rs1727132 chr7:99812297 T/C cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs6964587 1.000 rs3753109 chr7:91630001 G/C cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs4253772 0.530 rs6008662 chr22:46713917 G/A cg24881330 chr22:46731750 TRMU 0.96 6.17 0.48 8.81e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs3806843 0.900 rs3756334 chr5:140213796 G/A cg19875535 chr5:140030758 IK 0.37 5.94 0.47 2.67e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2880765 0.835 rs4536419 chr15:86039471 C/T cg13263323 chr15:86062960 AKAP13 -0.21 -4.5 -0.37 1.53e-5 Coronary artery disease; TGCT cis rs9811920 0.609 rs793466 chr3:99609837 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.82 -0.52 3.63e-10 Axial length; TGCT cis rs2594989 1.000 rs2594978 chr3:11383347 C/A cg00170343 chr3:11313890 ATG7 0.68 5.19 0.42 8.47e-7 Circulating chemerin levels; TGCT cis rs259282 0.692 rs17693106 chr19:33125055 C/T cg26639809 chr19:33781782 NA -0.25 -5.19 -0.42 8.26e-7 Schizophrenia; TGCT cis rs929354 0.742 rs7784442 chr7:156934475 G/C cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs11874712 0.712 rs2578183 chr18:43676720 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.49 4.9 0.4 2.91e-6 Migraine - clinic-based; TGCT trans rs79643899 1 rs79643899 chr5:35429449 A/C cg16965576 chr1:245238552 EFCAB2 0.72 6.71 0.52 6.05e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs9303401 0.659 rs34275691 chr17:56736640 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs28595532 0.841 rs114107504 chr4:119771080 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs3796352 1.000 rs11718834 chr3:52963668 A/C cg15956490 chr3:53032818 SFMBT1 0.63 6.53 0.51 1.55e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9560113 0.622 rs4773388 chr13:112195250 A/C cg10483660 chr13:112241077 NA 0.3 4.51 0.38 1.47e-5 Menarche (age at onset); TGCT cis rs9788682 1.000 rs34138960 chr15:78831668 A/G cg24631222 chr15:78858424 CHRNA5 0.92 7.57 0.56 7.51e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs1538970 0.962 rs9429158 chr1:45821393 A/G cg05343316 chr1:45956843 TESK2 0.64 5.13 0.42 1.08e-6 Platelet count; TGCT cis rs74233809 0.901 rs4409766 chr10:104616663 A/G cg05855489 chr10:104503620 C10orf26 0.78 4.47 0.37 1.73e-5 Birth weight; TGCT trans rs1814175 0.817 rs11040700 chr11:50023832 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs36051895 0.664 rs10815154 chr9:5095538 G/A cg02405213 chr9:5042618 JAK2 -0.77 -10.81 -0.7 1.32e-19 Pediatric autoimmune diseases; TGCT cis rs6733011 0.500 rs11123754 chr2:99433782 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.73 -0.39 6.12e-6 Bipolar disorder; TGCT cis rs875971 0.862 rs1083554 chr7:65852341 T/C cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs17376456 0.825 rs10061377 chr5:93174513 T/C cg21475434 chr5:93447410 FAM172A 0.69 4.97 0.41 2.15e-6 Diabetic retinopathy; TGCT cis rs66573146 0.803 rs59809420 chr4:6969928 G/T cg05069807 chr4:6945702 TBC1D14 0.33 4.72 0.39 6.27e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4851254 0.660 rs4851250 chr2:100729293 T/C cg07810366 chr2:100720526 AFF3 -0.45 -4.66 -0.39 8.15e-6 Intelligence (multi-trait analysis); TGCT cis rs861020 0.582 rs630065 chr1:209998662 C/T cg05527609 chr1:210001259 C1orf107 0.86 7.45 0.56 1.39e-11 Orofacial clefts; TGCT cis rs7772486 0.875 rs9322043 chr6:146352690 A/G cg23711669 chr6:146136114 FBXO30 0.9 10.19 0.68 4.4e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9486715 0.830 rs1475748 chr6:97034143 T/C cg18709589 chr6:96969512 KIAA0776 -0.84 -8.23 -0.59 2.19e-13 Headache; TGCT cis rs6460942 0.915 rs62448620 chr7:12458170 C/T cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs6714710 0.603 rs34373359 chr2:98442202 G/A cg26665480 chr2:98280029 ACTR1B 0.66 6.27 0.49 5.45e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2777491 0.915 rs7180418 chr15:41629502 A/C cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.44 -0.68 1.07e-18 Ulcerative colitis; TGCT cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg20887711 chr4:1340912 KIAA1530 0.91 8.31 0.6 1.41e-13 Longevity; TGCT cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs13191362 0.507 rs2849527 chr6:163117932 G/T cg06582575 chr6:163149167 PACRG;PARK2 0.54 5.25 0.43 6.38e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2657888 1.000 rs28697089 chr12:56938703 A/G cg23932658 chr12:57637574 STAC3 -0.51 -4.73 -0.39 5.9e-6 Adiponectin levels; TGCT cis rs1153858 1.000 rs56850226 chr15:45633118 T/C cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Vitiligo; TGCT cis rs7582180 0.652 rs4851307 chr2:100971778 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.79 0.4 4.66e-6 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.548 rs8189475 chr12:38037115 C/T cg26384229 chr12:38710491 ALG10B 0.71 6.3 0.49 4.78e-9 Bladder cancer; TGCT cis rs6089584 0.861 rs2180302 chr20:60576369 A/G cg06108461 chr20:60628389 TAF4 -0.65 -9.34 -0.64 5.08e-16 Body mass index; TGCT cis rs7914558 0.899 rs7913682 chr10:104684392 T/A cg15744005 chr10:104629667 AS3MT -0.43 -5.27 -0.43 5.86e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7659604 0.702 rs6826506 chr4:122710865 T/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.51 -0.44 1.95e-7 Type 2 diabetes; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg07205460 chr22:24236375 MIF 0.59 4.65 0.39 8.26e-6 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9916302 0.706 rs9890198 chr17:37457480 A/C cg07936489 chr17:37558343 FBXL20 0.85 6.28 0.49 5.22e-9 Glomerular filtration rate (creatinine); TGCT cis rs1862618 0.853 rs3099459 chr5:56137170 G/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs1532993 0.518 rs11097575 chr4:98642418 G/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.92 -0.4 2.72e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs597539 0.652 rs546382 chr11:68704264 C/T cg06028808 chr11:68637592 NA 0.54 6.94 0.53 1.93e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13256369 0.826 rs12678414 chr8:8586016 G/T cg18904891 chr8:8559673 CLDN23 0.54 4.63 0.38 9.19e-6 Obesity-related traits; TGCT cis rs112591243 0.685 rs4819263 chr21:47950866 G/A cg10657630 chr21:48055338 PRMT2 1.06 5.21 0.42 7.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9916302 0.706 rs8182252 chr17:37727950 T/C cg15445000 chr17:37608096 MED1 -0.34 -4.73 -0.39 6.02e-6 Glomerular filtration rate (creatinine); TGCT cis rs7226408 0.901 rs56209075 chr18:34386033 C/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT trans rs2243480 1.000 rs1796228 chr7:66033084 G/A cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs6835098 0.924 rs2332669 chr4:174163398 G/A cg08422745 chr4:174089978 GALNT7 -0.85 -9.14 -0.63 1.49e-15 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs11249608 0.548 rs6875622 chr5:178451397 C/T cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs2544527 0.819 rs2693019 chr2:15922288 T/C cg26669897 chr2:15909070 NA 0.42 4.98 0.41 2.09e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs77633900 0.614 rs2439992 chr15:76863023 T/G cg21673338 chr15:77095150 SCAPER -0.49 -4.59 -0.38 1.08e-5 Non-glioblastoma glioma;Glioma; TGCT cis rs9291683 0.509 rs10939671 chr4:10050815 T/C cg00071950 chr4:10020882 SLC2A9 0.57 6.43 0.5 2.5e-9 Bone mineral density; TGCT cis rs28785552 0.769 rs28796114 chr19:53234319 T/C cg04754360 chr19:53238445 ZNF611 -0.59 -4.55 -0.38 1.26e-5 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs9467773 1.000 rs1078679 chr6:26568741 C/T cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.39 0.5 3.07e-9 Cognitive function; TGCT cis rs7043114 0.525 rs10761161 chr9:95262342 C/G cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.39 -0.44 3.43e-7 Height; TGCT cis rs1018836 0.608 rs11997663 chr8:91474484 A/C cg16814680 chr8:91681699 NA -0.71 -7.18 -0.54 5.67e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7043114 0.525 rs7026361 chr9:95138564 A/C cg14631576 chr9:95140430 CENPP 0.29 4.82 0.4 4.05e-6 Height; TGCT cis rs2799081 1 rs2799081 chr6:28270584 T/C cg18815343 chr6:28367644 ZSCAN12 -0.47 -4.65 -0.39 8.23e-6 Myopia; TGCT cis rs17076896 0.655 rs61956063 chr13:19928471 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2228479 0.850 rs17226666 chr16:89835401 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs1577917 0.572 rs911927 chr6:86327860 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.52 -4.76 -0.39 5.23e-6 Response to antipsychotic treatment; TGCT cis rs9457247 0.967 rs447042 chr6:167405435 C/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs11910985 1.000 rs11910985 chr21:48042766 C/T cg23283320 chr21:48055893 PRMT2 1.35 6.43 0.5 2.51e-9 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs308403 0.509 rs13117125 chr4:123670824 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.84 0.73 4.22e-22 Blood protein levels; TGCT cis rs6089829 0.962 rs7267951 chr20:61665979 A/G cg18188782 chr20:61659543 NA 0.46 5.55 0.45 1.61e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg04234412 chr22:24373322 LOC391322 -0.78 -8.55 -0.61 3.78e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs5769707 0.604 rs1018814 chr22:50036900 T/C cg06623630 chr22:50017776 C22orf34 -0.27 -4.67 -0.39 7.81e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs3960554 0.529 rs7793844 chr7:75883147 C/T cg19105122 chr7:75896889 SRRM3 0.58 4.91 0.4 2.85e-6 Eotaxin levels; TGCT cis rs11731606 0.508 rs28501313 chr4:95281023 G/A cg00507259 chr4:95128692 SMARCAD1 0.65 4.89 0.4 3.02e-6 Mean platelet volume; TGCT trans rs1974653 0.672 rs8139374 chr22:20093522 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs2204008 0.774 rs8189620 chr12:38241621 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.42 0.55 1.6e-11 Bladder cancer; TGCT trans rs11722228 1.000 rs6825187 chr4:9915325 T/C cg26043149 chr18:55253948 FECH -0.74 -7.62 -0.56 5.78e-12 Gout;Urate levels;Serum uric acid levels; TGCT cis rs4372836 1.000 rs7579277 chr2:28996295 G/A cg09522027 chr2:28974177 PPP1CB -0.65 -5.74 -0.46 7.01e-8 Body mass index; TGCT cis rs3820068 0.705 rs72643701 chr1:15866219 G/A cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs2463822 0.920 rs28678254 chr11:62151875 G/C cg06239285 chr11:62104954 ASRGL1 -0.94 -6.61 -0.51 1.03e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs752092 0.894 rs8036083 chr15:101767822 T/G cg25114630 chr15:101792522 CHSY1 0.51 4.8 0.4 4.54e-6 Corneal structure; TGCT cis rs597539 0.652 rs488363 chr11:68658298 C/G cg21862992 chr11:68658383 NA 0.47 6.54 0.51 1.42e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6546537 0.869 rs13035491 chr2:69827456 G/A cg10773587 chr2:69614142 GFPT1 -0.72 -6.73 -0.52 5.54e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs9952991 0.941 rs9952749 chr18:12780456 A/G cg24737193 chr18:12778029 NA 0.53 5.93 0.47 2.8e-8 Inflammatory skin disease; TGCT cis rs7618915 1.000 rs7618915 chr3:52279594 G/A cg07507251 chr3:52567010 NT5DC2 0.43 5.83 0.46 4.46e-8 Bipolar disorder; TGCT cis rs62103177 0.564 rs11874805 chr18:77697110 T/C cg12964065 chr18:77638022 KCNG2 0.33 4.7 0.39 6.68e-6 Opioid sensitivity; TGCT cis rs3782455 1.000 rs75409372 chr12:114405283 C/T cg23502203 chr12:113549970 RASAL1 -0.57 -4.95 -0.41 2.34e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9611519 0.780 rs9611546 chr22:41698542 C/G cg13695892 chr22:41940480 POLR3H -0.71 -6.86 -0.52 2.89e-10 Neuroticism; TGCT cis rs1801251 0.752 rs709938 chr2:233746457 C/T cg25237894 chr2:233734115 C2orf82 -0.31 -5.98 -0.47 2.2e-8 Coronary artery disease; TGCT cis rs7246657 0.722 rs2927739 chr19:38149330 C/A cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT trans rs901683 0.702 rs73292848 chr10:46169752 T/C cg03236627 chr11:44786104 TSPAN18 -0.58 -6.72 -0.52 5.96e-10 Red blood cell traits;Mean corpuscular volume; TGCT cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.52 -4.87 -0.4 3.3e-6 Prudent dietary pattern; TGCT cis rs8103278 0.864 rs2070737 chr19:46282890 A/T cg14061069 chr19:46274453 DMPK -0.43 -6.29 -0.49 5e-9 Coronary artery disease; TGCT cis rs2836950 0.565 rs2836934 chr21:40564885 A/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.7 -0.39 6.68e-6 Menarche (age at onset); TGCT cis rs1555895 0.576 rs2274376 chr10:850157 A/G cg02193355 chr10:851439 NA 0.21 4.71 0.39 6.42e-6 Survival in rectal cancer; TGCT cis rs1997103 1.000 rs2331064 chr7:55408610 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs295140 1.000 rs1431766 chr2:201191034 A/G cg04283868 chr2:201171347 SPATS2L 0.64 6.63 0.51 9.15e-10 QT interval; TGCT cis rs72781680 1.000 rs56068891 chr2:24230633 A/G cg08917208 chr2:24149416 ATAD2B 0.84 5.12 0.42 1.12e-6 Lymphocyte counts; TGCT cis rs5750830 0.649 rs5757659 chr22:39812409 A/C cg11247378 chr22:39784982 NA -0.73 -9.57 -0.65 1.37e-16 Intelligence (multi-trait analysis); TGCT cis rs7095607 0.606 rs10998011 chr10:69958623 A/G cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs8177253 1.000 rs1525892 chr3:133484712 C/T cg01448562 chr3:133502909 NA -0.33 -6.78 -0.52 4.41e-10 Iron status biomarkers; TGCT cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg13012494 chr21:47604986 C21orf56 0.38 4.56 0.38 1.21e-5 Testicular germ cell tumor; TGCT cis rs2663905 0.706 rs2683260 chr15:81385552 A/C cg25029264 chr15:81426347 C15orf26 -0.69 -5.23 -0.42 7.14e-7 QT interval (drug interaction); TGCT cis rs13256369 0.802 rs13280101 chr8:8562773 G/A cg17143192 chr8:8559678 CLDN23 0.56 5.31 0.43 4.9e-7 Obesity-related traits; TGCT trans rs57221529 0.766 rs4081847 chr5:574072 C/T cg11887960 chr12:57824829 NA 1.1 9.51 0.65 1.98e-16 Lung disease severity in cystic fibrosis; TGCT cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg24549020 chr5:56110836 MAP3K1 0.66 5.79 0.46 5.56e-8 Initial pursuit acceleration; TGCT cis rs7772486 0.875 rs2814875 chr6:146305810 G/A cg23711669 chr6:146136114 FBXO30 0.88 9.48 0.65 2.31e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4851266 1.000 rs11123817 chr2:100835032 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.41 -0.44 3.1e-7 Educational attainment; TGCT cis rs2721195 0.683 rs6989368 chr8:145813457 A/G cg15857475 chr8:145742913 RECQL4;LRRC14 0.97 10.18 0.67 4.71e-18 Age at first birth; TGCT cis rs6542838 0.582 rs6542845 chr2:99537600 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.59 -5.57 -0.45 1.49e-7 Fear of minor pain; TGCT cis rs2836950 0.565 rs2836945 chr21:40596757 C/T cg11890956 chr21:40555474 PSMG1 -0.7 -6.87 -0.52 2.79e-10 Menarche (age at onset); TGCT cis rs6901250 0.655 rs1398404 chr6:117126345 A/C cg12892004 chr6:117198278 RFX6 0.45 5.65 0.45 1.05e-7 C-reactive protein levels; TGCT cis rs9926296 0.656 rs4522419 chr16:89853307 T/C cg08627397 chr16:89984028 MC1R -0.31 -4.83 -0.4 3.92e-6 Vitiligo; TGCT cis rs1472147 0.744 rs34692078 chr7:128488456 T/C cg00260937 chr7:128520193 KCP 0.41 5.68 0.45 9.1e-8 Calcium levels; TGCT cis rs4780401 0.610 rs933574 chr16:11792700 A/C cg01061890 chr16:11836724 TXNDC11 -0.47 -4.71 -0.39 6.59e-6 Rheumatoid arthritis; TGCT cis rs8017423 0.935 rs3742668 chr14:90767759 G/A cg04374321 chr14:90722782 PSMC1 -0.75 -7.14 -0.54 6.96e-11 Mortality in heart failure; TGCT cis rs3008870 0.792 rs72673729 chr1:67441673 T/TG cg11518657 chr1:67396239 MIER1 -0.53 -4.59 -0.38 1.08e-5 Lymphocyte percentage of white cells; TGCT cis rs13202913 0.837 rs9383901 chr6:151788059 T/A cg03627880 chr6:151815985 C6orf97 -0.76 -5.88 -0.47 3.48e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7772486 0.558 rs9376965 chr6:146130055 G/A cg05347473 chr6:146136440 FBXO30 0.66 6.2 0.49 7.78e-9 Lobe attachment (rater-scored or self-reported); TGCT trans rs916888 0.610 rs199536 chr17:44820425 T/C cg10053473 chr17:62856997 LRRC37A3 0.4 6.77 0.52 4.68e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6964587 0.967 rs41371748 chr7:91708219 A/G cg17063962 chr7:91808500 NA 0.84 8.41 0.6 8.2e-14 Breast cancer; TGCT cis rs7246657 0.943 rs8106839 chr19:37958475 C/G cg18154014 chr19:37997991 ZNF793 0.81 5.85 0.46 4.18e-8 Coronary artery calcification; TGCT cis rs10504229 0.817 rs55949560 chr8:58167603 T/C cg08280861 chr8:58055591 NA 0.32 4.46 0.37 1.83e-5 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.817 rs7947526 chr11:49983654 T/C cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs319204 1.000 rs319241 chr5:146236889 G/A cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs4746818 1.000 rs1506769 chr10:70959710 T/C cg04149295 chr10:70884716 VPS26A 0.8 5.41 0.44 3.1e-7 Left atrial antero-posterior diameter; TGCT cis rs4808199 0.895 rs2163805 chr19:19575945 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.73 5.16 0.42 9.65e-7 Nonalcoholic fatty liver disease; TGCT cis rs1577917 1.000 rs12204015 chr6:86598334 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.32 -0.43 4.59e-7 Response to antipsychotic treatment; TGCT cis rs2153535 0.541 rs1414347 chr6:8471831 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.73 0.46 7.1e-8 Motion sickness; TGCT cis rs736408 0.677 rs1042779 chr3:52821011 A/G cg07507251 chr3:52567010 NT5DC2 0.49 6.82 0.52 3.48e-10 Bipolar disorder; TGCT cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg11494091 chr17:61959527 GH2 -0.43 -7.2 -0.54 5.18e-11 Height; TGCT cis rs763121 0.819 rs5757161 chr22:38990662 G/A cg06022373 chr22:39101656 GTPBP1 0.79 7.98 0.58 8.44e-13 Menopause (age at onset); TGCT cis rs72615157 0.645 rs11771660 chr7:99851269 T/A cg00814883 chr7:100076585 TSC22D4 -0.58 -5.56 -0.45 1.57e-7 Lung function (FEV1/FVC); TGCT cis rs7666738 0.830 rs1896154 chr4:99021161 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.6 6.38 0.5 3.26e-9 Height; TGCT cis rs9549367 0.713 rs4907593 chr13:113830459 C/T cg18105134 chr13:113819100 PROZ 0.47 8.52 0.61 4.58e-14 Platelet distribution width; TGCT cis rs1395 0.925 rs1659696 chr2:27407831 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.5 -6.75 -0.52 5.06e-10 Blood metabolite levels; TGCT cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg03264133 chr6:25882463 NA 0.65 6.05 0.48 1.58e-8 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.931 rs9311432 chr3:48850443 T/A cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs3099143 1.000 rs3099142 chr15:77104909 C/T cg21673338 chr15:77095150 SCAPER -0.52 -4.97 -0.41 2.15e-6 Recalcitrant atopic dermatitis; TGCT cis rs763121 0.925 rs1043312 chr22:39131727 T/G cg06022373 chr22:39101656 GTPBP1 0.7 6.71 0.52 6.11e-10 Menopause (age at onset); TGCT cis rs1362404 0.614 rs9928406 chr16:51995705 A/T cg00216305 chr16:51625890 NA 0.25 4.44 0.37 1.95e-5 Gut microbiota (bacterial taxa); TGCT cis rs546131 0.928 rs547504 chr11:34847225 G/T cg06937548 chr11:34938143 PDHX;APIP 0.63 5.59 0.45 1.41e-7 Lung disease severity in cystic fibrosis; TGCT cis rs778371 0.676 rs2293780 chr2:233635213 T/C cg08000102 chr2:233561755 GIGYF2 0.72 8.68 0.61 1.91e-14 Schizophrenia; TGCT cis rs6969780 0.673 rs2301721 chr7:27196113 C/T cg22997113 chr7:27170241 HOXA4 -0.44 -4.46 -0.37 1.79e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6754311 0.684 rs11681248 chr2:136820076 C/T cg07169764 chr2:136633963 MCM6 -0.54 -5.31 -0.43 4.8e-7 Mosquito bite size; TGCT cis rs2932538 0.961 rs4240534 chr1:113175429 T/A cg22162597 chr1:113214053 CAPZA1 -0.27 -5.98 -0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs6570726 0.791 rs9373466 chr6:145912016 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.28 0.64 7.13e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs12477438 0.520 rs7605843 chr2:99811894 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.04 0.76 5.31e-25 Chronic sinus infection; TGCT cis rs12580194 0.593 rs55659159 chr12:55747754 C/T cg10672482 chr12:55725839 OR6C3 -0.52 -4.66 -0.39 8.13e-6 Cancer; TGCT cis rs1891498 0.602 rs10793707 chr1:147244022 G/A cg17941330 chr1:147245494 GJA5 0.36 4.79 0.4 4.62e-6 Cognitive performance; TGCT cis rs526231 0.578 rs1898672 chr5:102293853 A/T cg23492399 chr5:102201601 PAM 0.51 4.48 0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs3772130 0.962 rs11706783 chr3:121534322 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs9611565 0.649 rs2064189 chr22:42127999 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.83 0.4 3.93e-6 Vitiligo; TGCT cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg09323728 chr8:95962352 TP53INP1 -0.41 -4.79 -0.39 4.72e-6 Type 2 diabetes; TGCT cis rs73198271 0.740 rs10112989 chr8:8647334 A/C cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs11614062 1.000 rs11614062 chr12:93956672 A/T cg18151635 chr12:93972918 NA -0.21 -4.74 -0.39 5.83e-6 Height; TGCT cis rs9653442 0.527 rs12712064 chr2:100756548 C/T cg07810366 chr2:100720526 AFF3 -0.35 -5.0 -0.41 1.88e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7954584 0.531 rs1154514 chr12:122374888 C/T cg22618164 chr12:122356400 WDR66 0.69 6.48 0.5 1.93e-9 Mean corpuscular volume; TGCT cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg22029157 chr1:209979665 IRF6 -0.74 -6.21 -0.49 7.49e-9 Cleft lip with or without cleft palate; TGCT cis rs68170813 0.559 rs7807648 chr7:106965091 C/T cg02696742 chr7:106810147 HBP1 -0.67 -5.75 -0.46 6.63e-8 Coronary artery disease; TGCT cis rs7565124 0.955 rs11096638 chr2:20266386 G/T cg00462460 chr2:20212509 MATN3 -0.43 -4.66 -0.39 8.1e-6 Major depressive disorder; TGCT cis rs7100689 0.646 rs9804236 chr10:82135100 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs873917 0.620 rs784595 chr1:40135017 C/T cg18438793 chr1:40149837 HPCAL4 0.52 4.74 0.39 5.77e-6 Amyotrophic lateral sclerosis; TGCT cis rs7412746 0.658 rs3768015 chr1:150812954 C/T cg09365446 chr1:150670422 GOLPH3L 0.37 5.34 0.43 4.18e-7 Melanoma; TGCT cis rs806215 0.526 rs11768841 chr7:127551403 T/C cg11539674 chr7:127291444 SND1 -0.36 -4.67 -0.39 7.76e-6 Type 2 diabetes; TGCT cis rs614226 1.000 rs591992 chr12:121019323 T/C cg01236616 chr12:121019343 POP5 1.31 14.0 0.78 2.71e-27 Type 1 diabetes nephropathy; TGCT cis rs892961 0.899 rs35217221 chr17:75412385 G/A cg05865280 chr17:75406074 SEPT9 0.29 6.93 0.53 1.99e-10 Airflow obstruction; TGCT cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6586163 0.872 rs1926197 chr10:90748626 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.38 -4.78 -0.39 4.79e-6 Chronic lymphocytic leukemia; TGCT cis rs860295 0.580 rs2016251 chr1:155914988 C/T cg13795986 chr1:155880507 RIT1 0.36 4.45 0.37 1.87e-5 Body mass index; TGCT cis rs35306767 0.714 rs12767171 chr10:1084491 A/G cg20503657 chr10:835505 NA 0.45 5.05 0.41 1.51e-6 Eosinophil percentage of granulocytes; TGCT cis rs2404602 0.692 rs4641709 chr15:77047736 C/T cg22467129 chr15:76604101 ETFA 0.45 5.11 0.42 1.2e-6 Blood metabolite levels; TGCT cis rs2013441 1.000 rs2526462 chr17:20079460 A/T cg18979559 chr17:20280153 CCDC144C -0.43 -4.46 -0.37 1.82e-5 Obesity-related traits; TGCT cis rs28595532 0.920 rs114382134 chr4:119733215 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs10986311 0.775 rs1984001 chr9:127137801 T/C cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.8 0.4 4.5e-6 Vitiligo; TGCT cis rs6121246 0.909 rs6058450 chr20:30343911 G/A cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs1577917 0.958 rs10944168 chr6:86680156 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.08 -0.41 1.37e-6 Response to antipsychotic treatment; TGCT cis rs11122272 0.705 rs2808599 chr1:231533482 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.53 -0.51 1.55e-9 Hemoglobin concentration; TGCT cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs9920506 0.518 rs11072774 chr15:78952697 C/T cg24631222 chr15:78858424 CHRNA5 0.73 5.0 0.41 1.91e-6 Post bronchodilator FEV1; TGCT cis rs9400467 0.537 rs12195305 chr6:111449228 G/A cg15721981 chr6:111408429 SLC16A10 0.75 4.74 0.39 5.66e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs4820539 1.000 rs4822362 chr22:23482744 C/A cg21100191 chr22:23484243 RTDR1 0.89 10.78 0.7 1.61e-19 Bone mineral density; TGCT cis rs4699052 0.625 rs28498687 chr4:104333731 T/C cg16532752 chr4:104119610 CENPE -0.54 -5.27 -0.43 5.78e-7 Testicular germ cell tumor; TGCT cis rs11098499 0.954 rs17006190 chr4:120418838 C/G cg09307838 chr4:120376055 NA 0.68 6.56 0.51 1.28e-9 Corneal astigmatism; TGCT cis rs35306767 0.714 rs17293608 chr10:1056252 C/T cg18964960 chr10:1102726 WDR37 0.74 5.46 0.44 2.52e-7 Eosinophil percentage of granulocytes; TGCT cis rs981844 0.712 rs55656103 chr4:154757478 T/C cg14289246 chr4:154710475 SFRP2 1.02 9.48 0.65 2.3e-16 Response to statins (LDL cholesterol change); TGCT cis rs9549260 0.755 rs9566553 chr13:41174231 A/G cg21288729 chr13:41239152 FOXO1 1.01 10.53 0.69 6.43e-19 Red blood cell count; TGCT cis rs9527 0.590 rs11191572 chr10:104893137 A/G cg15744005 chr10:104629667 AS3MT -0.43 -4.94 -0.41 2.45e-6 Arsenic metabolism; TGCT cis rs3741404 0.609 rs669913 chr11:63869879 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.72 7.32 0.55 2.78e-11 Platelet count; TGCT cis rs6964587 0.839 rs6950538 chr7:91417816 T/C cg22709100 chr7:91322751 NA 0.29 4.57 0.38 1.16e-5 Breast cancer; TGCT cis rs9814567 1.000 rs17694011 chr3:134213981 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs36051895 0.632 rs10116823 chr9:5171944 T/A cg02405213 chr9:5042618 JAK2 -0.72 -9.67 -0.66 7.86e-17 Pediatric autoimmune diseases; TGCT cis rs7312933 0.558 rs4768399 chr12:42742696 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.72 -0.46 7.52e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7918232 0.800 rs7907981 chr10:27444329 T/C cg14442939 chr10:27389572 ANKRD26 0.78 5.48 0.44 2.26e-7 Breast cancer; TGCT cis rs3845702 1.000 rs10497555 chr2:180864967 A/G cg01881094 chr2:180872142 CWC22 0.68 5.98 0.47 2.24e-8 Schizophrenia; TGCT cis rs854765 0.647 rs854767 chr17:18018263 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.71 -7.38 -0.55 1.95e-11 Total body bone mineral density; TGCT cis rs6684514 0.961 rs11264469 chr1:156276746 A/G cg16558208 chr1:156270281 VHLL 0.47 9.22 0.64 9.78e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9443645 0.901 rs4706077 chr6:79548845 G/A cg09184832 chr6:79620586 NA -0.48 -5.3 -0.43 5.16e-7 Intelligence (multi-trait analysis); TGCT cis rs17253792 0.822 rs75663029 chr14:56092385 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg22920501 chr2:26401640 FAM59B 0.77 5.98 0.47 2.26e-8 Gut microbiome composition (summer); TGCT trans rs6089829 0.855 rs6090203 chr20:61663632 G/A cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg00149659 chr3:10157352 C3orf10 0.85 5.83 0.46 4.48e-8 Alzheimer's disease; TGCT cis rs7772486 0.713 rs79248977 chr6:146319388 C/A cg05347473 chr6:146136440 FBXO30 0.55 5.06 0.41 1.5e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3784262 0.616 rs2704197 chr15:58323236 C/T cg12031962 chr15:58353849 ALDH1A2 -0.38 -5.58 -0.45 1.45e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs1814175 0.754 rs7103235 chr11:49699191 A/G cg03929089 chr4:120376271 NA -0.71 -8.31 -0.6 1.43e-13 Height; TGCT cis rs7666738 0.830 rs7663661 chr4:99014761 A/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg10295955 chr4:187884368 NA 0.99 15.42 0.81 1.32e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs13118159 0.527 rs1250119 chr4:1261336 G/A cg20887711 chr4:1340912 KIAA1530 -0.99 -9.19 -0.64 1.17e-15 Longevity; TGCT cis rs881375 1.000 rs10818480 chr9:123643170 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.5 0.37 1.52e-5 Rheumatoid arthritis; TGCT cis rs7552167 0.925 rs78312791 chr1:24513613 C/A cg01960748 chr1:24522592 NA 0.46 5.14 0.42 1.02e-6 Psoriasis vulgaris; TGCT cis rs7681440 0.746 rs10001067 chr4:90818216 C/G cg20003494 chr4:90757398 SNCA -0.54 -5.07 -0.41 1.41e-6 Dementia with Lewy bodies; TGCT cis rs7666738 0.830 rs4699600 chr4:99019429 C/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.716 rs7656233 chr4:99079237 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.01 0.41 1.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4319547 0.695 rs4758666 chr12:122902840 C/T cg05707623 chr12:122985044 ZCCHC8 -0.64 -4.99 -0.41 1.98e-6 Body mass index; TGCT cis rs11098499 0.954 rs28429722 chr4:120300093 G/A cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs79149102 0.579 rs78434425 chr15:75304754 C/T cg09165964 chr15:75287851 SCAMP5 -1.04 -5.46 -0.44 2.48e-7 Lung cancer; TGCT cis rs933688 1.000 rs7720132 chr5:90745105 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.25 0.6 1.91e-13 Smoking behavior; TGCT cis rs801193 1.000 rs2286684 chr7:66129830 G/T cg18876405 chr7:65276391 NA -0.34 -5.19 -0.42 8.37e-7 Aortic root size; TGCT cis rs1552244 0.572 rs7645667 chr3:10157337 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.55 0.45 1.62e-7 Alzheimer's disease; TGCT cis rs10751667 0.666 rs10902249 chr11:958566 C/T cg06064525 chr11:970664 AP2A2 0.35 8.12 0.59 4.04e-13 Alzheimer's disease (late onset); TGCT cis rs597539 0.652 rs602805 chr11:68662076 A/T cg06112835 chr11:68658793 MRPL21 0.47 8.09 0.59 4.66e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2841277 0.770 rs10149193 chr14:105403474 C/T cg21017887 chr14:105400489 NA 0.38 5.42 0.44 3.03e-7 Rheumatoid arthritis; TGCT cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg27535305 chr1:53392650 SCP2 0.26 5.15 0.42 1e-6 Monocyte count; TGCT cis rs7666738 0.830 rs10022331 chr4:98960392 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 1.000 rs6083828 chr20:25369918 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7917772 0.503 rs7087665 chr10:104282418 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1153858 1.000 rs1145081 chr15:45679667 C/G cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs6121246 0.909 rs57726761 chr20:30314046 A/G cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.43 -4.73 -0.39 5.94e-6 Blood metabolite levels; TGCT cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg25036284 chr2:26402008 FAM59B -0.61 -4.89 -0.4 3.1e-6 Gut microbiome composition (summer); TGCT cis rs9811920 0.609 rs809415 chr3:99582242 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.55 0.51 1.35e-9 Axial length; TGCT cis rs57994353 0.865 rs35857370 chr9:139354097 G/A cg13741927 chr9:139327495 INPP5E -0.26 -6.0 -0.47 2.05e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9388451 0.839 rs3966775 chr6:126067655 C/A cg10911889 chr6:126070802 HEY2 0.57 6.05 0.48 1.56e-8 Brugada syndrome; TGCT cis rs7654585 0.962 rs2309289 chr4:25947094 T/A cg10409131 chr4:25915609 C4orf52 0.75 7.81 0.57 2.06e-12 Obesity-related traits; TGCT cis rs79976124 0.797 rs77895756 chr6:66626782 C/T cg07460842 chr6:66804631 NA 0.58 5.32 0.43 4.77e-7 Type 2 diabetes; TGCT cis rs7772486 0.654 rs702321 chr6:146006695 A/G cg23711669 chr6:146136114 FBXO30 -0.85 -9.45 -0.65 2.66e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs72843506 0.722 rs9895177 chr17:20207594 T/A cg18979559 chr17:20280153 CCDC144C -0.65 -4.86 -0.4 3.54e-6 Schizophrenia; TGCT cis rs8111998 0.826 rs4932777 chr19:22766764 C/T cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs734999 0.545 rs7368105 chr1:2556548 C/T cg18854424 chr1:2615690 NA 0.45 5.15 0.42 1e-6 Ulcerative colitis; TGCT cis rs2439831 1.000 rs2467736 chr15:43784917 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.19 0.59 2.67e-13 Lung cancer in ever smokers; TGCT cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg11941060 chr3:133502564 NA -0.26 -5.43 -0.44 2.88e-7 Iron status biomarkers; TGCT cis rs739496 0.579 rs3742000 chr12:112338539 A/G cg10833066 chr12:111807467 FAM109A 0.35 5.41 0.44 3.12e-7 Platelet count; TGCT cis rs4700695 0.719 rs27084 chr5:65435286 G/A cg21114390 chr5:65439923 SFRS12 -0.85 -7.61 -0.56 5.94e-12 Facial morphology (factor 19); TGCT cis rs71435601 0.600 rs557197 chr2:21381781 T/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs17473412 0.892 rs77910830 chr5:122649995 T/C cg15125798 chr5:122621645 NA -0.61 -5.52 -0.44 1.9e-7 Total body bone mineral density; TGCT cis rs9393777 0.513 rs9295702 chr6:26634040 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.59 -5.33 -0.43 4.44e-7 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg05738196 chr6:26577821 NA 0.87 11.3 0.71 8.47e-21 Intelligence (multi-trait analysis); TGCT cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg24531977 chr5:56204891 C5orf35 -0.9 -8.25 -0.6 1.95e-13 Type 2 diabetes; TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs9814567 0.806 rs55835132 chr3:134325256 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.77 -7.21 -0.54 4.87e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3008870 0.755 rs1024230 chr1:67512920 A/C cg02640540 chr1:67518911 SLC35D1 0.65 5.79 0.46 5.46e-8 Lymphocyte percentage of white cells; TGCT cis rs36051895 0.632 rs10758674 chr9:5163645 G/A cg02405213 chr9:5042618 JAK2 -0.78 -10.38 -0.68 1.54e-18 Pediatric autoimmune diseases; TGCT cis rs6969780 1.000 rs73071548 chr7:27147430 A/G cg04321618 chr7:27170880 HOXA4 0.58 4.7 0.39 6.81e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs74006954 0.571 rs71465229 chr15:27674961 A/G cg21575005 chr15:28358302 HERC2 0.32 4.78 0.39 4.79e-6 Alzheimer's disease (cognitive decline); TGCT cis rs7208859 0.623 rs56018041 chr17:29059985 G/A cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4563143 0.514 rs112651366 chr19:29299704 A/T cg12756686 chr19:29218302 NA 0.67 5.15 0.42 9.79e-7 Methadone dose in opioid dependence; TGCT cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg08280861 chr8:58055591 NA 0.39 4.64 0.38 8.72e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115576008 chr4:119736967 T/C cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs9926296 0.744 rs164747 chr16:89708680 T/G cg01097406 chr16:89675127 NA 0.35 6.3 0.49 4.68e-9 Vitiligo; TGCT cis rs4455778 0.561 rs6977535 chr7:49001350 C/T cg26309511 chr7:48887640 NA 0.55 7.04 0.53 1.14e-10 Lung cancer in never smokers; TGCT cis rs7666738 0.830 rs13141752 chr4:98893128 G/A cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.81e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs881375 1.000 rs881375 chr9:123652898 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.53 0.38 1.35e-5 Rheumatoid arthritis; TGCT cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg24531977 chr5:56204891 C5orf35 -0.76 -7.43 -0.56 1.54e-11 Initial pursuit acceleration; TGCT cis rs17253792 0.822 rs74653073 chr14:56079528 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.53 -0.38 1.37e-5 Putamen volume; TGCT cis rs3784262 0.528 rs4646588 chr15:58304313 A/G cg12031962 chr15:58353849 ALDH1A2 0.38 5.52 0.44 1.89e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6424115 1.000 rs974698 chr1:24132785 C/T cg15997130 chr1:24165203 NA 0.88 9.6 0.65 1.19e-16 Immature fraction of reticulocytes; TGCT cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs921968 0.541 rs523937 chr2:219437596 G/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg13877915 chr19:58951672 ZNF132 -0.92 -11.95 -0.73 2.3e-22 Uric acid clearance; TGCT trans rs2288327 0.643 rs1559908 chr2:179336347 C/T cg18634211 chr1:26737262 LIN28 -0.91 -7.49 -0.56 1.11e-11 Atrial fibrillation; TGCT cis rs514406 0.679 rs541852 chr1:53256834 A/G cg22166914 chr1:53195759 ZYG11B -0.36 -5.93 -0.47 2.8e-8 Monocyte count; TGCT cis rs6912958 0.781 rs9450752 chr6:88300013 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs13082711 0.522 rs533175 chr3:27361432 A/G cg02860705 chr3:27208620 NA -0.29 -4.79 -0.39 4.72e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs9534288 0.797 rs2148414 chr13:46582368 G/T cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs514406 0.861 rs2477741 chr1:53265278 A/G cg08859206 chr1:53392774 SCP2 0.39 5.78 0.46 5.77e-8 Monocyte count; TGCT cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg18305652 chr10:134549665 INPP5A 0.33 5.54 0.45 1.74e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs72781680 0.898 rs72780111 chr2:23991146 G/A cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs7582180 0.629 rs6716636 chr2:100940067 C/G cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs2549003 1.000 rs7735073 chr5:131815357 G/A cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs11239930 0.560 rs632334 chr1:146551521 C/T cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs35306767 0.903 rs7074642 chr10:878359 A/G cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs6076065 0.748 rs4142246 chr20:23388975 A/G cg11657817 chr20:23433608 CST11 0.32 5.62 0.45 1.22e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs899997 1.000 rs11072793 chr15:79006442 C/T cg00061860 chr15:78953028 NA -0.26 -4.85 -0.4 3.63e-6 Coronary artery disease or large artery stroke; TGCT cis rs7172971 0.655 rs72727735 chr15:42342226 T/C cg05886115 chr15:42349113 NA 0.32 5.1 0.42 1.25e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs2996428 0.667 rs7538067 chr1:3761772 C/T cg17848003 chr1:3704513 LRRC47 0.19 5.14 0.42 1.04e-6 Red cell distribution width; TGCT cis rs9913156 0.793 rs55884013 chr17:4579301 G/A cg00122941 chr17:4613640 ARRB2 0.87 6.89 0.53 2.44e-10 Lymphocyte counts; TGCT cis rs17767294 0.708 rs72851156 chr6:28060086 T/C cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs12479064 0.694 rs4341989 chr2:100046783 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.77 -6.72 -0.52 6.03e-10 Chronic sinus infection; TGCT cis rs4851254 0.618 rs4851243 chr2:100639482 G/A cg22139774 chr2:100720529 AFF3 -0.45 -4.9 -0.4 2.94e-6 Intelligence (multi-trait analysis); TGCT cis rs617219 0.671 rs1316753 chr5:78531337 G/C cg23987322 chr5:78407566 BHMT 0.35 4.7 0.39 6.68e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6840360 0.571 rs12650655 chr4:152556075 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.698 rs6659228 chr1:46811027 C/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.67 -0.39 7.69e-6 Menopause (age at onset); TGCT cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs3796619 0.924 rs11940546 chr4:1072485 C/T cg27284194 chr4:1044797 NA 0.46 4.45 0.37 1.85e-5 Recombination rate (males); TGCT cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg15691649 chr6:25882328 NA -0.41 -4.75 -0.39 5.64e-6 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.647 rs12439141 chr15:77095423 T/C cg22467129 chr15:76604101 ETFA 0.48 4.7 0.39 6.7e-6 Blood metabolite levels; TGCT cis rs4936894 0.500 rs6590056 chr11:124170064 A/G cg27160556 chr11:124181099 OR8D1 0.33 4.5 0.37 1.54e-5 Aging (time to death); TGCT cis rs9638182 0.725 rs12056034 chr7:72878645 A/G cg14087351 chr7:73037990 MLXIPL -0.61 -4.81 -0.4 4.34e-6 Triglycerides; TGCT cis rs4975709 0.589 rs4975745 chr5:1861058 G/C cg15595755 chr5:1867978 NA 0.46 5.29 0.43 5.29e-7 Cardiovascular disease risk factors; TGCT cis rs6088580 0.634 rs6059866 chr20:33075810 A/C cg08999081 chr20:33150536 PIGU 0.29 5.83 0.46 4.46e-8 Glomerular filtration rate (creatinine); TGCT cis rs1552244 0.882 rs66559400 chr3:10012551 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg13395646 chr4:1353034 KIAA1530 -0.48 -5.8 -0.46 5.13e-8 Obesity-related traits; TGCT cis rs4689388 0.816 rs13147655 chr4:6293474 A/G cg14416269 chr4:6271139 WFS1 0.37 4.77 0.39 4.99e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7246657 0.882 rs4803539 chr19:37897522 A/C cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs6424115 0.708 rs12748109 chr1:24181177 C/T cg15997130 chr1:24165203 NA -0.7 -7.02 -0.53 1.26e-10 Immature fraction of reticulocytes; TGCT cis rs2033711 0.503 rs6510141 chr19:58885786 C/G cg13877915 chr19:58951672 ZNF132 -0.52 -5.02 -0.41 1.76e-6 Uric acid clearance; TGCT cis rs1215050 0.791 rs260890 chr4:98741698 A/G cg17366294 chr4:99064904 C4orf37 0.51 5.4 0.44 3.29e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9427116 0.967 rs7547072 chr1:154639255 A/G cg17218026 chr1:154582156 ADAR -0.2 -4.95 -0.41 2.32e-6 Blood protein levels; TGCT cis rs7666738 0.830 rs9884501 chr4:98893721 A/C cg17366294 chr4:99064904 C4orf37 0.68 6.87 0.53 2.72e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs5750830 0.649 rs5757664 chr22:39821536 A/G cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs1577917 0.727 rs2758840 chr6:86304625 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs40363 1.000 rs1690441 chr16:3517635 C/G cg05754148 chr16:3507555 NAT15 0.48 4.69 0.39 7.24e-6 Tuberculosis; TGCT cis rs1005224 0.927 rs8007792 chr14:76175666 C/A cg04684003 chr14:76127793 TTLL5;C14orf1 -0.71 -5.88 -0.47 3.58e-8 Large artery stroke; TGCT cis rs853679 0.538 rs13199081 chr6:28331834 T/C cg18815343 chr6:28367644 ZSCAN12 -0.53 -4.71 -0.39 6.63e-6 Depression; TGCT cis rs769267 0.930 rs10402451 chr19:19608537 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs6964587 0.869 rs6946764 chr7:91539003 A/G cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs7568458 0.660 rs2289972 chr2:85766545 C/T cg02493740 chr2:85810744 VAMP5 -0.29 -5.31 -0.43 4.91e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2468186 0.710 rs2450075 chr8:120093547 A/G cg02248809 chr8:120845432 TAF2 -0.42 -4.47 -0.37 1.72e-5 Osteoprotegerin levels; TGCT cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.844 rs6076343 chr20:25376663 C/T cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2204008 0.806 rs1589382 chr12:38408565 T/A cg13010199 chr12:38710504 ALG10B 0.61 4.86 0.4 3.44e-6 Bladder cancer; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg24846343 chr22:24311635 DDTL 0.22 5.62 0.45 1.19e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28735056 0.875 rs4239346 chr18:77641226 A/G cg20368463 chr18:77673604 PQLC1 0.4 4.82 0.4 4.16e-6 Schizophrenia; TGCT cis rs2839186 0.934 rs2839197 chr21:47708133 A/G cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs9858542 0.953 rs11706370 chr3:49441091 G/A cg03060546 chr3:49711283 APEH -0.63 -5.49 -0.44 2.18e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs42648 0.693 rs3747800 chr7:89899488 G/T cg25739043 chr7:89950458 NA -0.55 -5.12 -0.42 1.13e-6 Homocysteine levels; TGCT cis rs9560113 0.959 rs9560108 chr13:112180303 A/C cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs4566357 0.615 rs3769645 chr2:227913717 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.99 -0.41 1.97e-6 Coronary artery disease; TGCT cis rs7267979 0.816 rs422148 chr20:25512604 G/C cg03522245 chr20:25566470 NINL 0.56 5.79 0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9291683 0.632 rs12508991 chr4:10041104 C/T cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.31e-14 Bone mineral density; TGCT trans rs7726839 0.540 rs72703080 chr5:595238 A/G cg25482853 chr8:67687455 SGK3 1.26 10.61 0.69 4.22e-19 Obesity-related traits; TGCT cis rs892864 0.554 rs17608692 chr5:127682131 T/C cg01939274 chr5:127874478 FBN2 0.95 4.56 0.38 1.21e-5 Multiple system atrophy; TGCT cis rs2204008 0.542 rs34770471 chr12:38009613 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs634534 0.622 rs501353 chr11:65739549 T/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.56 5.35 0.43 4.04e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs319204 1.000 rs2082405 chr5:146258596 C/T cg25021259 chr5:146258546 PPP2R2B 0.38 4.64 0.38 8.81e-6 Schizophrenia; TGCT cis rs2073300 1.000 rs6114142 chr20:23461082 A/G cg09953122 chr20:23471693 CST8 -0.56 -4.45 -0.37 1.86e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT trans rs1814175 0.817 rs10128730 chr11:50023369 G/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs514406 0.800 rs4926930 chr1:53217335 A/G cg22166914 chr1:53195759 ZYG11B -0.41 -7.06 -0.54 1.05e-10 Monocyte count; TGCT cis rs7267979 1.000 rs2482941 chr20:25361216 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6918586 0.658 rs198825 chr6:26122502 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.68 -6.53 -0.51 1.52e-9 Schizophrenia; TGCT cis rs61990749 0.597 rs176952 chr14:78180736 T/C cg02301378 chr14:78227641 SNW1;C14orf178 0.63 4.62 0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs7666738 0.830 rs7696686 chr4:98938445 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs782590 0.967 rs782588 chr2:55841640 T/C cg03859395 chr2:55845619 SMEK2 0.92 11.37 0.71 5.88e-21 Metabolic syndrome; TGCT cis rs9913156 0.841 rs72824957 chr17:4590496 C/T cg19197139 chr17:4613644 ARRB2 0.83 7.74 0.57 3.03e-12 Lymphocyte counts; TGCT cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg11644478 chr21:40555479 PSMG1 -0.61 -5.74 -0.46 6.75e-8 Cognitive function; TGCT cis rs12681288 0.754 rs4735975 chr8:1000470 T/C cg04851639 chr8:1020857 NA -0.36 -6.43 -0.5 2.55e-9 Schizophrenia; TGCT cis rs7635838 0.590 rs2256773 chr3:11386329 C/G cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs78487399 0.710 rs7572923 chr2:43685109 C/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.19 -0.42 8.37e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4906332 1.000 rs8012127 chr14:103942762 G/A cg26031613 chr14:104095156 KLC1 -0.52 -4.72 -0.39 6.31e-6 Coronary artery disease; TGCT cis rs1891275 0.515 rs7911755 chr10:93489817 G/A cg07889827 chr10:93443413 NA -0.32 -6.71 -0.52 6.35e-10 Intelligence (multi-trait analysis); TGCT cis rs13256369 0.851 rs13271698 chr8:8567539 C/A cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs751728 0.544 rs2281820 chr6:33768897 A/G cg13859433 chr6:33739653 LEMD2 -0.32 -5.39 -0.44 3.43e-7 Crohn's disease; TGCT cis rs73001065 0.818 rs10500212 chr19:19723215 C/T cg03709012 chr19:19516395 GATAD2A 1.04 5.1 0.42 1.26e-6 LDL cholesterol; TGCT cis rs6089584 0.927 rs1886007 chr20:60581049 G/A cg06108461 chr20:60628389 TAF4 -0.58 -8.35 -0.6 1.14e-13 Body mass index; TGCT cis rs8180040 0.654 rs62246451 chr3:47211632 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.33 -0.6 1.26e-13 Colorectal cancer; TGCT cis rs2458413 0.521 rs2458427 chr8:105339594 G/T cg04554929 chr8:105342491 NA -0.63 -10.35 -0.68 1.77e-18 Paget's disease; TGCT cis rs9926296 0.605 rs6500449 chr16:89856393 T/C cg27121462 chr16:89883253 FANCA 0.81 8.95 0.63 4.42e-15 Vitiligo; TGCT cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg22508957 chr16:3507546 NAT15 0.54 6.18 0.49 8.58e-9 Tuberculosis; TGCT cis rs2228479 0.850 rs62054599 chr16:89808850 C/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7681440 0.904 rs6532193 chr4:90764188 G/A cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.82e-8 Dementia with Lewy bodies; TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg26354017 chr1:205819088 PM20D1 0.53 6.2 0.49 7.86e-9 Menarche (age at onset); TGCT cis rs6754311 0.593 rs10202489 chr2:136494186 G/A cg07169764 chr2:136633963 MCM6 -0.66 -6.12 -0.48 1.13e-8 Mosquito bite size; TGCT cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Crohn's disease;Inflammatory bowel disease; TGCT cis rs826838 1.000 rs851934 chr12:39104453 G/T cg26384229 chr12:38710491 ALG10B -0.85 -8.16 -0.59 3.22e-13 Heart rate; TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg08736216 chr1:53307985 ZYG11A -0.24 -4.74 -0.39 5.75e-6 Monocyte count; TGCT cis rs5769765 0.862 rs138897 chr22:50231067 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.75 -0.73 7.01e-22 Schizophrenia; TGCT cis rs875971 1.000 rs1182882 chr7:65562063 C/T cg18876405 chr7:65276391 NA -0.35 -5.31 -0.43 4.85e-7 Aortic root size; TGCT cis rs743757 0.608 rs175634 chr3:50644134 A/G cg08173110 chr3:50359005 HYAL2 0.69 4.59 0.38 1.09e-5 Diastolic blood pressure; TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.1 0.54 8.35e-11 Prudent dietary pattern; TGCT cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg06238570 chr21:40685208 BRWD1 -0.8 -9.02 -0.63 2.92e-15 Cognitive function; TGCT cis rs595982 0.527 rs17206707 chr19:49361441 A/C cg15549821 chr19:49342101 PLEKHA4 -0.74 -9.74 -0.66 5.46e-17 Red cell distribution width; TGCT cis rs9611565 0.512 rs6519289 chr22:42170432 A/C cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs727505 1.000 rs28702851 chr7:124442991 G/A cg23710748 chr7:124431027 NA -0.28 -4.9 -0.4 2.92e-6 Lewy body disease; TGCT cis rs12765878 1.000 rs11191865 chr10:105672842 G/A cg11005552 chr10:105648138 OBFC1 0.44 7.61 0.56 5.93e-12 Coronary artery disease; TGCT cis rs7119 0.635 rs2667764 chr15:77881239 C/T cg27398640 chr15:77910606 LINGO1 0.31 6.31 0.49 4.49e-9 Type 2 diabetes; TGCT cis rs11096990 0.634 rs2839765 chr4:39295553 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs2066819 1.000 rs2643623 chr12:56689725 G/C cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT trans rs804280 0.543 rs13261205 chr8:11791216 A/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Myopia (pathological); TGCT cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg16414030 chr3:133502952 NA -0.65 -10.78 -0.7 1.59e-19 Iron status biomarkers; TGCT cis rs6988636 1.000 rs28513831 chr8:124189208 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs7552404 1.000 rs11161511 chr1:76210477 A/G cg03433033 chr1:76189801 ACADM -0.79 -9.38 -0.64 4.11e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2658782 1.000 rs2658778 chr11:93148948 C/G cg18152523 chr11:93063302 CCDC67 -0.7 -5.35 -0.43 4.12e-7 Pulmonary function decline; TGCT cis rs617219 0.698 rs12189248 chr5:78517143 A/G cg05890484 chr5:78407552 BHMT -0.4 -5.47 -0.44 2.33e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6964587 0.900 rs7783674 chr7:91784212 T/A cg22709100 chr7:91322751 NA 0.29 4.68 0.39 7.32e-6 Breast cancer; TGCT cis rs9303401 0.659 rs11079357 chr17:56902778 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs116095464 0.558 rs6878061 chr5:223072 A/G cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs6484504 0.553 rs413067 chr11:31223497 T/C cg26647111 chr11:31128758 NA -0.34 -4.61 -0.38 9.92e-6 Red blood cell count; TGCT cis rs2455799 0.517 rs1466072 chr3:15939311 G/T cg12172478 chr3:16357591 RFTN1 -0.33 -4.81 -0.4 4.31e-6 Mean platelet volume; TGCT cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg08392591 chr16:89556376 ANKRD11 0.57 5.26 0.43 6.05e-7 Multiple myeloma (IgH translocation); TGCT cis rs1997103 1.000 rs11238364 chr7:55407632 G/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7267979 0.966 rs2227890 chr20:25260931 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2932538 0.922 rs11102508 chr1:113141175 T/C cg22162597 chr1:113214053 CAPZA1 0.25 5.6 0.45 1.34e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7769051 1.000 rs5006218 chr6:133126220 T/G cg07930552 chr6:133119739 C6orf192 0.94 5.09 0.42 1.28e-6 Type 2 diabetes nephropathy; TGCT cis rs6752107 1.000 rs12994997 chr2:234173503 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.65 0.39 8.35e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs12541335 0.639 rs35068739 chr8:22201719 T/C cg07298985 chr8:22133076 PIWIL2 0.34 5.42 0.44 3e-7 Hypertriglyceridemia; TGCT cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg10862848 chr6:42927986 GNMT -0.4 -4.98 -0.41 2.11e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs11190604 0.767 rs77838250 chr10:102180090 T/G cg16342193 chr10:102329863 NA -0.4 -5.02 -0.41 1.74e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11264213 0.901 rs630364 chr1:36449304 C/T cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs12477438 0.765 rs6737257 chr2:99683330 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg02503808 chr4:7069936 GRPEL1 0.98 9.23 0.64 9.22e-16 Monocyte percentage of white cells; TGCT cis rs2617583 0.509 rs4738 chr5:1461568 C/T cg13982541 chr5:1466431 LPCAT1 0.2 4.57 0.38 1.15e-5 Breast cancer; TGCT cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.6 -6.02 -0.48 1.84e-8 Intelligence (multi-trait analysis); TGCT cis rs60843830 1.000 rs59937473 chr2:271797 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.71 6.79 0.52 4.18e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9291683 0.561 rs3733584 chr4:10036506 T/C cg11266682 chr4:10021025 SLC2A9 0.64 8.92 0.63 5e-15 Bone mineral density; TGCT cis rs7959452 0.719 rs57954211 chr12:69748397 C/A cg11871910 chr12:69753446 YEATS4 0.85 9.48 0.65 2.25e-16 Blood protein levels; TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg26354017 chr1:205819088 PM20D1 -0.52 -6.45 -0.5 2.29e-9 Menarche (age at onset); TGCT cis rs6964587 0.869 rs7793946 chr7:91520628 T/C cg17063962 chr7:91808500 NA -0.86 -9.19 -0.64 1.16e-15 Breast cancer; TGCT cis rs11785400 0.762 rs7460801 chr8:143730972 C/A cg10596483 chr8:143751796 JRK 0.53 5.21 0.42 7.5e-7 Schizophrenia; TGCT cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg00684032 chr4:1343700 KIAA1530 0.23 4.9 0.4 2.95e-6 Obesity-related traits; TGCT cis rs933688 0.532 rs4916851 chr5:90536300 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.54 -4.68 -0.39 7.32e-6 Smoking behavior; TGCT cis rs2233152 0.572 rs10411008 chr19:41297241 T/C cg23743927 chr19:41304969 EGLN2 -0.65 -4.51 -0.38 1.47e-5 Kawasaki disease; TGCT cis rs7666738 0.830 rs7664340 chr4:99037820 C/T cg05340658 chr4:99064831 C4orf37 0.51 5.82 0.46 4.75e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10423674 0.526 rs757317 chr19:18819984 C/T cg20185461 chr19:18899082 COMP -0.53 -5.03 -0.41 1.68e-6 Menarche (age at onset); TGCT cis rs17767294 0.708 rs72851168 chr6:28080008 C/T cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs9500256 0.966 rs1322446 chr6:58311950 C/T cg16251399 chr6:58287822 GUSBL2 0.67 5.96 0.47 2.44e-8 Eosinophilic esophagitis (pediatric); TGCT cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs12510870 0.566 rs13115877 chr4:74460288 C/T cg05868023 chr4:75230803 EREG 0.56 5.01 0.41 1.83e-6 Iris color (b* coordinate); TGCT cis rs6684514 0.961 rs10908503 chr1:156300683 C/T cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7119 0.604 rs2682924 chr15:77863720 C/T cg27398640 chr15:77910606 LINGO1 -0.26 -4.75 -0.39 5.61e-6 Type 2 diabetes; TGCT cis rs1670533 1.000 rs6850784 chr4:1059809 G/A cg27284194 chr4:1044797 NA 0.69 5.96 0.47 2.44e-8 Recombination rate (females); TGCT cis rs1451375 0.698 rs1813214 chr7:50637525 A/G cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs10751667 0.666 rs7395267 chr11:962326 C/A cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT cis rs4664308 0.840 rs1870102 chr2:161070582 A/G cg03641300 chr2:160917029 PLA2R1 -0.25 -5.94 -0.47 2.7e-8 Idiopathic membranous nephropathy; TGCT cis rs3015497 0.648 rs10144512 chr14:51082271 A/C cg04730355 chr14:51134070 SAV1 -0.64 -6.17 -0.48 8.98e-9 Mean platelet volume; TGCT cis rs13217239 0.646 rs7768407 chr6:27016795 G/A cg26531700 chr6:26746687 NA 0.66 6.45 0.5 2.31e-9 Schizophrenia; TGCT cis rs6840360 0.571 rs4696100 chr4:152514242 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT trans rs804280 0.509 rs13268030 chr8:11783073 C/T cg15556689 chr8:8085844 FLJ10661 0.8 7.54 0.56 8.53e-12 Myopia (pathological); TGCT cis rs317689 0.581 rs315132 chr12:69761996 G/C cg19645103 chr12:69753606 YEATS4 -0.57 -4.8 -0.4 4.5e-6 Response to diuretic therapy; TGCT cis rs1577917 0.958 rs11756615 chr6:86679835 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.08 -0.41 1.37e-6 Response to antipsychotic treatment; TGCT cis rs11098499 0.863 rs6835635 chr4:120458867 A/G cg09307838 chr4:120376055 NA 0.7 6.7 0.52 6.41e-10 Corneal astigmatism; TGCT cis rs1062177 0.756 rs2964589 chr5:151118189 G/T cg00977110 chr5:151150581 G3BP1 -0.43 -4.82 -0.4 4.14e-6 Preschool internalizing problems; TGCT cis rs11096990 0.572 rs35040563 chr4:39155882 G/A cg20847110 chr4:39482781 LOC401127 0.17 4.96 0.41 2.28e-6 Cognitive function; TGCT cis rs2456568 0.741 rs10831137 chr11:93636912 C/T cg26875233 chr11:93583750 C11orf90 -0.48 -6.46 -0.5 2.1e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg04025307 chr7:1156635 C7orf50 0.22 5.32 0.43 4.6e-7 Longevity;Endometriosis; TGCT cis rs916888 0.779 rs199498 chr17:44865603 A/G cg01570182 chr17:44337453 NA 0.77 6.58 0.51 1.17e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3087591 0.922 rs9892839 chr17:29618990 A/G cg24425628 chr17:29625626 OMG;NF1 -0.49 -7.6 -0.56 6.42e-12 Hip circumference; TGCT cis rs4713118 0.513 rs156739 chr6:28013410 C/A cg10876282 chr6:28092338 ZSCAN16 0.52 4.88 0.4 3.15e-6 Parkinson's disease; TGCT cis rs5769765 0.955 rs9616204 chr22:50303530 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.41 5.84 0.46 4.39e-8 Schizophrenia; TGCT cis rs295140 0.903 rs56326533 chr2:201168758 T/C cg04283868 chr2:201171347 SPATS2L 0.6 5.95 0.47 2.55e-8 QT interval; TGCT cis rs6500602 0.789 rs2404546 chr16:4479734 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.16 0.42 9.6e-7 Schizophrenia; TGCT cis rs1461503 0.966 rs11218905 chr11:122840303 A/G cg27398637 chr11:122830231 C11orf63 0.41 5.2 0.42 8.05e-7 Menarche (age at onset); TGCT cis rs17767294 0.612 rs12332927 chr6:27955115 T/C cg08851530 chr6:28072375 NA 0.81 4.9 0.4 2.9e-6 Parkinson's disease; TGCT cis rs587847 0.505 rs599218 chr15:37685780 A/T cg16890051 chr15:37175029 LOC145845 -0.39 -4.57 -0.38 1.16e-5 Intraocular pressure; TGCT cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.1 0.42 1.24e-6 Menopause (age at onset); TGCT cis rs1008375 0.863 rs4698632 chr4:17614894 T/C cg18681998 chr4:17616180 MED28 1.0 10.56 0.69 5.37e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17376456 0.825 rs10079708 chr5:93261796 G/C cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg17054783 chr10:134559939 INPP5A 0.24 4.72 0.39 6.38e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs13108904 0.818 rs3775099 chr4:1232510 C/G cg03303774 chr4:1407052 NA 0.28 4.5 0.37 1.54e-5 Obesity-related traits; TGCT cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs8072100 0.871 rs7206971 chr17:45425115 A/G cg08085267 chr17:45401833 C17orf57 0.45 5.06 0.41 1.46e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg03303774 chr4:1407052 NA 0.31 4.87 0.4 3.31e-6 Obesity-related traits; TGCT cis rs7975161 0.630 rs4246264 chr12:104637743 C/G cg25273343 chr12:104657179 TXNRD1 -0.35 -4.83 -0.4 3.87e-6 Toenail selenium levels; TGCT cis rs9926296 0.609 rs4785710 chr16:89796756 C/T cg04287289 chr16:89883240 FANCA -0.64 -6.46 -0.5 2.16e-9 Vitiligo; TGCT cis rs10992471 0.729 rs7042335 chr9:95122547 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.26 -0.49 5.87e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7246657 0.654 rs10407568 chr19:38123009 A/T cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.7e-6 Coronary artery calcification; TGCT cis rs6882046 0.513 rs254779 chr5:88019629 T/C cg24804195 chr5:87968844 LOC645323 -0.57 -5.57 -0.45 1.5e-7 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs6964587 1.000 rs10280927 chr7:91582205 G/A cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs72945132 0.882 rs3900797 chr11:70186614 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9325144 0.647 rs61937754 chr12:39060543 T/C cg10518543 chr12:38710700 ALG10B -0.48 -4.47 -0.37 1.77e-5 Morning vs. evening chronotype; TGCT cis rs12679857 0.686 rs1032129 chr8:119951900 A/C cg17171407 chr8:119960777 TNFRSF11B 0.33 5.95 0.47 2.51e-8 Type 1 diabetes; TGCT trans rs1814175 0.647 rs10769646 chr11:49992204 C/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs4776059 1.000 rs12915981 chr15:52901433 C/T cg25063058 chr15:52860530 ARPP19 0.53 4.76 0.39 5.22e-6 Schizophrenia; TGCT cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg10047753 chr17:41438598 NA 0.96 9.54 0.65 1.61e-16 Menopause (age at onset); TGCT cis rs7914558 1.000 rs4917380 chr10:104775335 C/G cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.34e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7312933 0.558 rs1796388 chr12:42785987 G/C cg19980929 chr12:42632907 YAF2 -0.4 -5.7 -0.46 8.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs896854 0.517 rs9643353 chr8:95957063 A/G cg13393036 chr8:95962371 TP53INP1 0.49 5.83 0.46 4.61e-8 Type 2 diabetes; TGCT cis rs1401999 0.714 rs7646621 chr3:183640865 A/C cg01324343 chr3:183735012 ABCC5 -0.72 -8.93 -0.63 4.7e-15 Anterior chamber depth; TGCT cis rs12935418 0.616 rs11859567 chr16:80969848 A/G cg07676361 chr16:80966860 NA -0.35 -4.69 -0.39 6.99e-6 Mean corpuscular volume; TGCT cis rs7584330 0.518 rs113812061 chr2:238447934 T/C cg14458575 chr2:238380390 NA 0.43 4.56 0.38 1.23e-5 Prostate cancer; TGCT cis rs734999 0.967 rs6667605 chr1:2502780 C/T cg18854424 chr1:2615690 NA 0.47 5.92 0.47 3.01e-8 Ulcerative colitis; TGCT cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg05985448 chr10:134359359 INPP5A -0.22 -4.97 -0.41 2.15e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs7824557 0.564 rs7821459 chr8:11236681 T/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs7216064 0.628 rs62084702 chr17:66043157 C/T cg12091567 chr17:66097778 LOC651250 1.08 8.86 0.62 7.21e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9926296 0.572 rs2376878 chr16:89885161 G/A cg03388025 chr16:89894329 SPIRE2 0.34 5.01 0.41 1.81e-6 Vitiligo; TGCT cis rs61895110 1 rs61895110 chr11:47557160 G/A cg13308137 chr11:47528955 CUGBP1 0.48 5.21 0.42 7.78e-7 Total body bone mineral density; TGCT cis rs2295359 1.000 rs9729046 chr1:67607082 C/G cg03340356 chr1:67600835 NA 0.37 4.48 0.37 1.66e-5 Psoriasis; TGCT cis rs12477438 0.798 rs2309524 chr2:99659510 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs12681287 0.547 rs10956873 chr8:87547028 T/C cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT cis rs9486719 0.901 rs760619 chr6:96857431 A/G cg18709589 chr6:96969512 KIAA0776 0.68 4.93 0.4 2.63e-6 Migraine;Coronary artery disease; TGCT cis rs6964587 1.000 rs2075881 chr7:91734552 T/C cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.21e-5 Breast cancer; TGCT cis rs1008375 1.000 rs6819132 chr4:17689752 G/T cg10189774 chr4:17578691 LAP3 -0.61 -5.25 -0.43 6.52e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4499344 0.730 rs35098593 chr19:33103939 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.63 0.61 2.53e-14 Mean platelet volume; TGCT cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg11644478 chr21:40555479 PSMG1 -0.53 -4.57 -0.38 1.17e-5 Cognitive function; TGCT cis rs6484504 0.576 rs208103 chr11:31167400 A/G cg26647111 chr11:31128758 NA -0.34 -4.6 -0.38 1.02e-5 Red blood cell count; TGCT cis rs10193935 1.000 rs10190326 chr2:42388262 A/C cg27598129 chr2:42591480 NA 0.39 5.07 0.41 1.39e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 0.647 rs116505114 chr15:77074794 T/C cg23625390 chr15:77176239 SCAPER -0.37 -4.69 -0.39 7.04e-6 Blood metabolite levels; TGCT cis rs2033711 0.870 rs4801270 chr19:58932762 C/A cg13877915 chr19:58951672 ZNF132 0.88 11.12 0.71 2.43e-20 Uric acid clearance; TGCT cis rs447921 0.861 rs423130 chr17:74416189 A/G cg09812376 chr17:74270190 QRICH2 0.46 4.6 0.38 1.01e-5 Mitochondrial DNA levels; TGCT cis rs1949733 0.917 rs10461079 chr4:8392724 G/A cg11789530 chr4:8429930 ACOX3 -0.55 -4.94 -0.41 2.51e-6 Response to antineoplastic agents; TGCT cis rs3793683 0.928 rs10781585 chr10:134553369 C/A cg27286337 chr10:134555280 INPP5A -0.47 -7.34 -0.55 2.52e-11 Migraine; TGCT cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg20849893 chr7:64541193 NA 0.5 5.21 0.42 7.7e-7 Calcium levels; TGCT cis rs5750830 0.649 rs5757657 chr22:39798429 G/T cg02038168 chr22:39784481 NA -0.77 -6.65 -0.51 8.24e-10 Intelligence (multi-trait analysis); TGCT cis rs2241685 0.850 rs58404476 chr2:1936998 C/T cg21862353 chr2:1801628 MYT1L -0.53 -4.86 -0.4 3.47e-6 Attention deficit hyperactivity disorder; TGCT cis rs3812831 0.599 rs428636 chr13:114927133 T/C cg08824895 chr13:115047677 UPF3A 0.48 4.66 0.39 8.08e-6 Schizophrenia; TGCT cis rs4595586 0.525 rs12812749 chr12:39363254 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.45 0.37 1.92e-5 Morning vs. evening chronotype; TGCT cis rs62064224 0.589 rs8069673 chr17:30661250 C/T cg18200150 chr17:30822561 MYO1D -0.39 -4.58 -0.38 1.13e-5 Schizophrenia; TGCT cis rs981844 1.000 rs10517579 chr4:154666321 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs4746818 0.793 rs2805913 chr10:70858062 A/G cg11621586 chr10:70884670 VPS26A 1.04 8.35 0.6 1.13e-13 Left atrial antero-posterior diameter; TGCT cis rs9913156 0.793 rs56020376 chr17:4560909 A/G cg19197139 chr17:4613644 ARRB2 0.86 7.9 0.58 1.32e-12 Lymphocyte counts; TGCT cis rs6909279 0.678 rs11753987 chr6:151851428 T/C cg14416726 chr6:151773293 C6orf211;RMND1 0.62 5.66 0.45 9.77e-8 Bone mineral density; TGCT cis rs4478858 0.746 rs60073066 chr1:31689589 G/A cg00250761 chr1:31883323 NA 0.29 4.88 0.4 3.25e-6 Alcohol dependence; TGCT cis rs68170813 0.522 rs12154818 chr7:107074515 G/C cg02696742 chr7:106810147 HBP1 -0.67 -5.69 -0.46 8.58e-8 Coronary artery disease; TGCT cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg09177884 chr7:1199841 ZFAND2A -0.51 -4.84 -0.4 3.76e-6 Longevity;Endometriosis; TGCT cis rs4975709 0.589 rs1466607 chr5:1864856 A/G cg15595755 chr5:1867978 NA 0.46 5.45 0.44 2.62e-7 Cardiovascular disease risk factors; TGCT cis rs2576037 0.562 rs9959877 chr18:44522293 T/A cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.68 -0.39 7.26e-6 Personality dimensions; TGCT cis rs6681544 0.510 rs3790910 chr1:82378937 A/G cg04226724 chr1:82268649 LPHN2 0.47 4.95 0.41 2.33e-6 Metabolite levels (X-11787); TGCT cis rs6547741 0.563 rs10196039 chr2:27971195 C/T cg27432699 chr2:27873401 GPN1 -0.22 -5.4 -0.44 3.34e-7 Oral cavity cancer; TGCT cis rs6565180 1.000 rs12930787 chr16:30381303 C/G cg17640201 chr16:30407289 ZNF48 -0.91 -8.83 -0.62 8.55e-15 Tonsillectomy; TGCT cis rs1023500 1.000 rs1047997 chr22:42334953 C/G cg04692870 chr22:42525206 CYP2D6 -0.35 -5.26 -0.43 6.16e-7 Schizophrenia; TGCT cis rs11098499 0.779 rs10016060 chr4:120298412 A/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs2228479 0.702 rs62056092 chr16:89930426 A/G cg06558623 chr16:89946397 TCF25 0.52 4.6 0.38 1.05e-5 Skin colour saturation; TGCT cis rs7582180 0.790 rs4851288 chr2:100920451 T/C cg08017756 chr2:100939284 LONRF2 -0.32 -5.4 -0.44 3.2e-7 Intelligence (multi-trait analysis); TGCT cis rs344364 0.511 rs12596510 chr16:1949480 G/A cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs1056107 0.541 rs10739349 chr9:115178029 C/A cg02332936 chr9:115140584 NA -0.27 -4.6 -0.38 1.02e-5 Colorectal cancer; TGCT cis rs11673344 0.523 rs6510585 chr19:37553983 C/T cg08039142 chr19:36980659 ZNF566 0.49 4.5 0.37 1.57e-5 Obesity-related traits; TGCT cis rs2235642 0.717 rs2236269 chr16:1652614 T/A cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.63 -0.38 9.16e-6 Coronary artery disease; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.42 6.05 0.48 1.57e-8 Lymphocyte counts; TGCT cis rs11249608 0.548 rs10479519 chr5:178450693 T/C cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs860554 1.000 rs860554 chr1:201262432 A/G cg01022117 chr1:201258280 PKP1 -0.31 -4.85 -0.4 3.6e-6 Panic disorder; TGCT cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.27 0.49 5.58e-9 Mean platelet volume; TGCT cis rs6089829 0.962 rs57684920 chr20:61662639 G/A cg08045932 chr20:61659980 NA -0.45 -8.05 -0.59 5.73e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg22166914 chr1:53195759 ZYG11B 0.34 5.42 0.44 2.95e-7 Monocyte count; TGCT cis rs9902453 0.845 rs2321493 chr17:28230359 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.26 0.55 3.67e-11 Coffee consumption (cups per day); TGCT cis rs3008870 0.701 rs2815358 chr1:67493778 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.17 0.59 3.04e-13 Lymphocyte percentage of white cells; TGCT cis rs7833790 0.724 rs12676336 chr8:82771008 C/T cg06027949 chr8:82754900 SNX16 0.67 5.14 0.42 1.06e-6 Diastolic blood pressure; TGCT cis rs9322193 0.886 rs9322198 chr6:149944908 T/C cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs17376456 0.825 rs28645862 chr5:93233128 G/C cg25358565 chr5:93447407 FAM172A 1.01 8.13 0.59 3.77e-13 Diabetic retinopathy; TGCT cis rs922182 0.692 rs7162147 chr15:64291500 G/A cg02919090 chr15:64263738 DAPK2 0.27 4.71 0.39 6.62e-6 Blood protein levels; TGCT cis rs6988636 1.000 rs28537152 chr8:124189071 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs7647973 0.588 rs9883000 chr3:49667691 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.65 0.39 8.24e-6 Menarche (age at onset); TGCT cis rs2307449 0.892 rs2238301 chr15:89851438 C/T cg24365117 chr15:89879190 POLG -0.32 -4.51 -0.38 1.51e-5 Menopause (age at onset); TGCT cis rs7582180 0.607 rs1530029 chr2:100968205 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.82 -0.4 4.16e-6 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg06481639 chr22:41940642 POLR3H -0.72 -6.52 -0.51 1.61e-9 Vitiligo; TGCT cis rs11623869 0.711 rs2403173 chr14:103909289 T/C cg12935359 chr14:103987150 CKB -0.33 -4.84 -0.4 3.86e-6 Bone mineral density; TGCT cis rs12681288 0.676 rs935819 chr8:1021814 T/C cg04851639 chr8:1020857 NA -0.36 -6.56 -0.51 1.31e-9 Schizophrenia; TGCT cis rs2836974 0.932 rs8129416 chr21:40617145 C/T cg11644478 chr21:40555479 PSMG1 1.0 10.69 0.69 2.7e-19 Cognitive function; TGCT cis rs10832963 1.000 rs2084220 chr11:18656932 C/T cg09201001 chr11:18656081 SPTY2D1 1.04 11.74 0.73 7.48e-22 Breast cancer; TGCT cis rs7917772 0.503 rs2031601 chr10:104308064 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 8.6 0.61 2.97e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs796364 1.000 rs35220450 chr2:200780737 T/C cg17644776 chr2:200775616 C2orf69 -0.31 -4.83 -0.4 3.99e-6 Schizophrenia; TGCT cis rs11690462 0.929 rs11678646 chr2:26602262 C/T cg04726446 chr2:26624865 C2orf39 0.43 4.66 0.39 8.15e-6 Coronary artery disease; TGCT cis rs9486719 0.656 rs4839826 chr6:96853616 A/G cg06623918 chr6:96969491 KIAA0776 -0.91 -7.71 -0.57 3.55e-12 Migraine;Coronary artery disease; TGCT cis rs9394841 0.656 rs9349209 chr6:41940546 G/A cg08135965 chr6:41755394 TOMM6 0.51 4.62 0.38 9.47e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs13242816 1.000 rs13247987 chr7:116113344 A/C cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs17253792 0.822 rs8007065 chr14:56081272 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7666738 0.791 rs10017624 chr4:98984009 G/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT trans rs72809171 0.661 rs72809197 chr17:12493710 C/G cg03074370 chr19:50352995 PTOV1 0.51 6.93 0.53 1.99e-10 Male-pattern baldness; TGCT cis rs7208859 0.673 rs12103588 chr17:29197460 C/T cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg06640241 chr16:89574553 SPG7 0.81 9.15 0.64 1.39e-15 Multiple myeloma (IgH translocation); TGCT cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg26338869 chr17:61819248 STRADA -0.58 -5.23 -0.43 6.97e-7 Prudent dietary pattern; TGCT cis rs7786808 0.552 rs4909207 chr7:158187136 G/A cg01191920 chr7:158217561 PTPRN2 -0.37 -5.44 -0.44 2.67e-7 Obesity-related traits; TGCT cis rs8077577 0.945 rs62073604 chr17:18065888 T/C cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs12579753 0.879 rs1987116 chr12:82156478 G/A cg07988820 chr12:82153109 PPFIA2 -0.67 -7.45 -0.56 1.4e-11 Resting heart rate; TGCT cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg02579736 chr3:10068473 FANCD2;CIDECP -0.9 -5.8 -0.46 5.19e-8 Alzheimer's disease; TGCT cis rs13188771 0.651 rs68082730 chr5:100903250 C/T cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs2882877 0.610 rs1123109 chr2:190444392 C/T cg10752008 chr2:190445175 SLC40A1 -0.79 -6.23 -0.49 6.62e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs10875746 0.903 rs886588 chr12:48477422 A/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg07157834 chr1:205819609 PM20D1 0.43 6.9 0.53 2.38e-10 Menarche (age at onset); TGCT trans rs9951602 0.512 rs12454617 chr18:76656007 C/T cg02800362 chr5:177631904 HNRNPAB 1.13 12.71 0.75 3.32e-24 Obesity-related traits; TGCT cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs4918072 0.874 rs3850670 chr10:105659369 C/T cg11005552 chr10:105648138 OBFC1 0.41 5.4 0.44 3.29e-7 Coronary artery disease; TGCT cis rs12971120 0.947 rs8084410 chr18:72168486 T/C cg25817165 chr18:72167213 CNDP2 -0.29 -5.51 -0.44 1.98e-7 Refractive error; TGCT cis rs11711311 0.955 rs3796254 chr3:113380332 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.8 -7.13 -0.54 7.24e-11 IgG glycosylation; TGCT cis rs10242455 0.571 rs28365067 chr7:99272310 G/A cg25640893 chr7:99214727 ZNF498 0.96 4.44 0.37 2e-5 Blood metabolite levels; TGCT cis rs9902453 1.000 rs55971458 chr17:28427016 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.52 0.51 1.63e-9 Coffee consumption (cups per day); TGCT cis rs12893668 0.703 rs34186780 chr14:104027595 T/G cg26031613 chr14:104095156 KLC1 -0.54 -4.55 -0.38 1.28e-5 Reticulocyte count; TGCT cis rs72781680 0.848 rs56021814 chr2:24073437 T/A cg08917208 chr2:24149416 ATAD2B 0.72 4.44 0.37 1.96e-5 Lymphocyte counts; TGCT cis rs40363 0.645 rs250629 chr16:3525431 C/A cg22508957 chr16:3507546 NAT15 0.48 5.48 0.44 2.31e-7 Tuberculosis; TGCT trans rs2727020 0.521 rs4980445 chr11:49570183 C/T cg11707556 chr5:10655725 ANKRD33B -0.42 -8.32 -0.6 1.34e-13 Coronary artery disease; TGCT cis rs35883536 0.647 rs55728953 chr1:101046863 T/C cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs116095464 0.558 rs10065584 chr5:253997 G/A cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT cis rs79149102 0.579 rs74023908 chr15:75310710 T/C cg09165964 chr15:75287851 SCAMP5 -1.05 -5.73 -0.46 7.26e-8 Lung cancer; TGCT cis rs10089 1.000 rs9968597 chr5:127455383 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.17 0.59 2.99e-13 Ileal carcinoids; TGCT cis rs9638182 1.000 rs34594435 chr7:72977249 C/T cg14087351 chr7:73037990 MLXIPL -0.58 -4.91 -0.4 2.83e-6 Triglycerides; TGCT cis rs950169 0.840 rs4842854 chr15:84942339 T/G cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs7614311 0.681 rs2241822 chr3:63965304 A/G cg22134162 chr3:63841271 THOC7 -0.45 -5.73 -0.46 7.3e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg04352962 chr1:209979756 IRF6 0.66 4.87 0.4 3.28e-6 Cleft lip with or without cleft palate; TGCT cis rs2404602 0.716 rs12917430 chr15:76674360 T/C cg26408565 chr15:76604113 ETFA -0.4 -5.09 -0.42 1.28e-6 Blood metabolite levels; TGCT cis rs78487399 0.808 rs74600494 chr2:43743491 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.02 -0.41 1.75e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6956675 0.830 rs4585626 chr7:62671592 C/G cg27518014 chr7:62859535 LOC100287834 -0.49 -4.65 -0.38 8.54e-6 Obesity-related traits; TGCT cis rs5769765 0.954 rs5770739 chr22:50268014 C/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs6598955 0.670 rs3795688 chr1:26560481 C/A cg04990556 chr1:26633338 UBXN11 -0.91 -11.87 -0.73 3.59e-22 Obesity-related traits; TGCT cis rs2820315 0.867 rs2819348 chr1:201884952 T/C cg12730843 chr1:201915899 LMOD1 -0.27 -4.82 -0.4 4.17e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2204008 0.692 rs11613378 chr12:38213138 T/A cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg12310025 chr6:25882481 NA -0.54 -5.7 -0.46 8.31e-8 Height; TGCT cis rs6545883 0.868 rs2427885 chr2:61816777 A/G cg15711740 chr2:61764176 XPO1 -0.59 -5.51 -0.44 1.97e-7 Tuberculosis; TGCT cis rs6500602 0.702 rs56895104 chr16:4548132 G/A cg08645402 chr16:4508243 NA 0.18 5.15 0.42 1.01e-6 Schizophrenia; TGCT cis rs514406 0.525 rs269291 chr1:53189297 C/T cg08859206 chr1:53392774 SCP2 -0.35 -4.91 -0.4 2.76e-6 Monocyte count; TGCT cis rs17376456 0.825 rs28412976 chr5:93248377 T/C cg25358565 chr5:93447407 FAM172A 1.01 7.59 0.56 6.78e-12 Diabetic retinopathy; TGCT cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg08439880 chr3:133502540 NA -0.28 -5.15 -0.42 9.73e-7 Iron status biomarkers; TGCT cis rs155076 1.000 rs9509638 chr13:21860193 G/A cg14456004 chr13:21872349 NA -1.23 -9.97 -0.67 1.49e-17 White matter hyperintensity burden; TGCT cis rs2832191 0.716 rs7284006 chr21:30475186 T/A cg08807101 chr21:30365312 RNF160 0.67 6.13 0.48 1.08e-8 Dental caries; TGCT cis rs7727544 0.514 rs3846728 chr5:131436217 G/A cg24060327 chr5:131705240 SLC22A5 -0.45 -4.48 -0.37 1.64e-5 Blood metabolite levels; TGCT cis rs6540559 0.673 rs17317411 chr1:209961314 C/T cg21951975 chr1:209979733 IRF6 -0.67 -4.99 -0.41 2.03e-6 Cleft lip with or without cleft palate; TGCT cis rs769267 1.000 rs2285627 chr19:19467937 T/C cg02546618 chr19:19431379 KIAA0892;SF4 -0.68 -5.66 -0.45 9.97e-8 Tonsillectomy; TGCT cis rs7647973 0.626 rs4855846 chr3:49683526 G/A cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs35785195 0.593 rs35304519 chr12:114236677 C/T cg11070030 chr12:114232702 NA 0.26 4.45 0.37 1.9e-5 Daytime sleep phenotypes; TGCT cis rs3782455 1.000 rs16943542 chr12:114406301 C/T cg23502203 chr12:113549970 RASAL1 -0.57 -4.92 -0.4 2.64e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10782582 0.593 rs12132750 chr1:76136222 A/G cg03433033 chr1:76189801 ACADM -0.63 -7.25 -0.55 3.83e-11 Daytime sleep phenotypes; TGCT cis rs918629 0.761 rs3777173 chr5:95281353 C/T cg16656078 chr5:95278638 ELL2 -0.28 -4.52 -0.38 1.42e-5 IgG glycosylation; TGCT cis rs4494114 0.902 rs12751382 chr1:39307275 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.43 -0.5 2.52e-9 Blood protein levels; TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs9814567 0.712 rs4306900 chr3:134334327 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.73 6.66 0.51 7.8e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1865760 1.000 rs7757666 chr6:25902626 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs259282 0.605 rs17692992 chr19:33099430 T/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.61 5.43 0.44 2.85e-7 Schizophrenia; TGCT cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg17971929 chr21:40555470 PSMG1 0.97 9.52 0.65 1.86e-16 Cognitive function; TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.73 -7.36 -0.55 2.27e-11 Prudent dietary pattern; TGCT cis rs422249 0.547 rs102275 chr11:61557803 T/C cg01500311 chr11:61656094 FADS3 -0.36 -6.37 -0.5 3.28e-9 Trans fatty acid levels; TGCT cis rs2180341 0.920 rs9401951 chr6:127671632 A/C cg27446573 chr6:127587934 RNF146 1.22 10.94 0.7 6.36e-20 Breast cancer; TGCT cis rs709400 0.663 rs10133035 chr14:103979127 C/T cg26031613 chr14:104095156 KLC1 0.86 9.54 0.65 1.61e-16 Body mass index; TGCT cis rs858239 0.601 rs10278700 chr7:23160529 T/C cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2016266 0.929 rs11170495 chr12:53665202 G/A cg16917193 chr12:54089295 NA 0.65 5.36 0.43 3.98e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs9653442 0.564 rs10197987 chr2:100790783 A/T cg22139774 chr2:100720529 AFF3 -0.34 -5.27 -0.43 5.98e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6831352 0.734 rs12502237 chr4:100015675 G/A cg12011299 chr4:100065546 ADH4 0.38 5.02 0.41 1.78e-6 Alcohol dependence; TGCT cis rs7267979 1.000 rs4815424 chr20:25390284 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg07424592 chr7:64974309 NA 1.39 8.24 0.59 2.08e-13 Diabetic kidney disease; TGCT cis rs61931739 0.500 rs11053140 chr12:34316122 T/C cg06521331 chr12:34319734 NA -0.3 -4.45 -0.37 1.87e-5 Morning vs. evening chronotype; TGCT cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg12756686 chr19:29218302 NA 0.78 6.69 0.51 6.93e-10 Methadone dose in opioid dependence; TGCT cis rs1670533 1.000 rs2290411 chr4:1051077 T/C cg20887711 chr4:1340912 KIAA1530 0.7 5.66 0.45 9.77e-8 Recombination rate (females); TGCT cis rs6121246 0.567 rs6120890 chr20:30207659 T/G cg13852791 chr20:30311386 BCL2L1 0.7 4.68 0.39 7.29e-6 Mean corpuscular hemoglobin; TGCT cis rs2404602 0.692 rs66866130 chr15:77128574 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.21e-6 Blood metabolite levels; TGCT cis rs7666738 0.716 rs13108535 chr4:99046324 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10479542 0.702 rs13183521 chr5:178975606 A/G cg19723775 chr5:179050963 HNRNPH1 -0.48 -4.73 -0.39 6.1e-6 Lung cancer; TGCT cis rs2197308 0.605 rs2387437 chr12:37919367 T/C cg13010199 chr12:38710504 ALG10B 0.61 4.93 0.4 2.57e-6 Morning vs. evening chronotype; TGCT cis rs6570726 0.526 rs72994723 chr6:145722948 G/A cg23711669 chr6:146136114 FBXO30 -0.56 -4.99 -0.41 1.96e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg05738196 chr6:26577821 NA -0.85 -10.7 -0.69 2.5e-19 Intelligence (multi-trait analysis); TGCT cis rs7914558 0.966 rs7096269 chr10:104736721 A/G cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.34e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs8141529 0.748 rs9620841 chr22:29290981 C/T cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs3772130 0.961 rs1573819 chr3:121469646 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.53 4.7 0.39 6.84e-6 Cognitive performance; TGCT cis rs10479542 0.929 rs7718673 chr5:178980009 C/T cg19626725 chr5:178986131 RUFY1 -0.44 -5.46 -0.44 2.52e-7 Lung cancer; TGCT cis rs6920965 0.527 rs584032 chr6:126165003 G/A cg05901451 chr6:126070800 HEY2 0.56 5.11 0.42 1.18e-6 High light scatter reticulocyte count; TGCT cis rs4566357 0.595 rs6707159 chr2:227909339 T/A cg11843606 chr2:227700838 RHBDD1 -0.52 -4.92 -0.4 2.71e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs11727653 chr4:99001774 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.680 rs11097613 chr4:99079991 G/T cg17366294 chr4:99064904 C4orf37 0.68 6.58 0.51 1.19e-9 Colonoscopy-negative controls vs population controls; TGCT trans rs877282 0.945 rs12776447 chr10:790625 A/G cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs769267 0.965 rs7254230 chr19:19434350 C/T cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs11105298 0.891 rs8181784 chr12:89828591 A/G cg00757033 chr12:89920650 WDR51B 0.31 4.92 0.4 2.72e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT trans rs1496653 0.602 rs71322187 chr3:23473926 T/C cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs3771570 1.000 rs12619369 chr2:242282957 A/T cg21155796 chr2:242212141 HDLBP 0.91 6.86 0.52 2.85e-10 Prostate cancer; TGCT cis rs769267 1.000 rs7247309 chr19:19439631 A/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs861020 1.000 rs674433 chr1:209964875 A/C cg05527609 chr1:210001259 C1orf107 -0.92 -8.19 -0.59 2.71e-13 Orofacial clefts; TGCT cis rs12580194 0.593 rs7311751 chr12:55748847 A/G cg10672482 chr12:55725839 OR6C3 -0.51 -4.58 -0.38 1.13e-5 Cancer; TGCT cis rs6964587 0.967 rs2188153 chr7:91595117 G/T cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs11671005 0.735 rs11666303 chr19:58922502 T/G cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.93 -6.86 -0.52 2.86e-10 Gut microbiome composition (summer); TGCT cis rs67311347 0.822 rs9826847 chr3:40345312 A/T cg13683864 chr3:40499215 RPL14 -0.9 -8.68 -0.61 1.87e-14 Renal cell carcinoma; TGCT cis rs9653442 0.564 rs12992234 chr2:100767886 G/A cg22139774 chr2:100720529 AFF3 -0.35 -5.55 -0.45 1.63e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7258465 0.965 rs1560118 chr19:18570035 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.51 0.38 1.5e-5 Breast cancer; TGCT cis rs877282 0.945 rs877280 chr10:771599 C/T cg17470449 chr10:769945 NA 0.31 4.77 0.39 5.04e-6 Uric acid levels; TGCT cis rs2692947 0.637 rs1168967 chr2:96826016 A/G cg22654517 chr2:96458247 NA 0.23 5.1 0.42 1.22e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs968451 0.865 rs12627970 chr22:39721745 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.84 8.54 0.61 4.02e-14 Primary biliary cholangitis; TGCT cis rs908922 0.676 rs7547628 chr1:152527738 T/C cg20991723 chr1:152506922 NA 0.45 6.06 0.48 1.55e-8 Hair morphology; TGCT cis rs35306767 0.714 rs17293608 chr10:1056252 C/T cg26597838 chr10:835615 NA 0.57 6.57 0.51 1.23e-9 Eosinophil percentage of granulocytes; TGCT cis rs12911832 1.000 rs12911832 chr15:58985904 A/T cg05156742 chr15:59063176 FAM63B 0.5 4.78 0.39 4.94e-6 Schizophrenia; TGCT cis rs1997103 1.000 rs6976824 chr7:55396115 A/C cg17469321 chr7:55412551 NA 0.62 6.55 0.51 1.35e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs644799 1.000 rs693597 chr11:95589629 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 10.76 0.7 1.74e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11190604 1.000 rs7079756 chr10:102302105 G/A cg16342193 chr10:102329863 NA -0.41 -4.98 -0.41 2.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10507380 0.824 rs77417706 chr13:27919510 G/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs2204008 0.540 rs3908193 chr12:38410907 G/T cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Bladder cancer; TGCT cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg10117171 chr1:25599238 RHD -0.32 -5.22 -0.42 7.21e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg10117171 chr1:25599238 RHD -0.35 -5.7 -0.46 8.2e-8 Erythrocyte sedimentation rate; TGCT cis rs9677476 0.516 rs2303351 chr2:232030510 C/A cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs12510870 0.599 rs16849675 chr4:74452122 C/T cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs6088590 0.813 rs1884668 chr20:33285514 A/G cg08999081 chr20:33150536 PIGU 0.27 5.01 0.41 1.81e-6 Coronary artery disease; TGCT cis rs7017914 0.967 rs17689955 chr8:71848864 C/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.29 -0.43 5.39e-7 Bone mineral density; TGCT cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs9660180 0.967 rs10907191 chr1:1774820 A/T cg23982607 chr1:1823379 GNB1 -0.56 -8.56 -0.61 3.65e-14 Body mass index; TGCT trans rs8073060 0.586 rs6505485 chr17:33996102 C/T cg19694781 chr19:47549865 TMEM160 -0.59 -10.9 -0.7 8.12e-20 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7666738 0.519 rs28539191 chr4:98821552 C/T cg17366294 chr4:99064904 C4orf37 0.65 5.96 0.47 2.39e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs34891900 0.507 rs1008378 chr22:18207251 T/C cg19898043 chr22:18121309 BCL2L13 0.55 4.7 0.39 6.8e-6 Sum neutrophil eosinophil counts; TGCT trans rs7618501 0.633 rs2252833 chr3:50004209 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.87 9.39 0.64 3.82e-16 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.875 rs9373485 chr6:146401429 A/T cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 0.692 rs2137307 chr15:77149020 T/A cg26408565 chr15:76604113 ETFA -0.36 -4.53 -0.38 1.36e-5 Blood metabolite levels; TGCT cis rs8177253 1.000 rs1358023 chr3:133484393 T/C cg20276088 chr3:133502917 NA -0.24 -5.02 -0.41 1.74e-6 Iron status biomarkers; TGCT cis rs1018836 0.818 rs715057 chr8:91624340 T/C cg16814680 chr8:91681699 NA -0.78 -8.2 -0.59 2.54e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs778371 0.522 rs6704768 chr2:233592501 C/T cg08000102 chr2:233561755 GIGYF2 0.63 7.17 0.54 5.87e-11 Schizophrenia; TGCT cis rs514406 0.861 rs1412706 chr1:53237721 G/A cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs17376456 0.877 rs55832164 chr5:93436579 C/T cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs35160687 0.901 rs12622200 chr2:86498595 A/G cg03171300 chr2:86307199 POLR1A -0.32 -5.49 -0.44 2.18e-7 Night sleep phenotypes; TGCT cis rs12541335 0.639 rs4871994 chr8:22206038 G/A cg02788857 chr8:22132959 PIWIL2 0.28 5.09 0.42 1.29e-6 Hypertriglyceridemia; TGCT cis rs10771431 0.817 rs10843149 chr12:9362067 G/A cg08997352 chr12:9597637 DDX12 -0.26 -5.24 -0.43 6.71e-7 Breast size; TGCT cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1797081 1.000 rs812426 chr10:16857133 C/G cg14835575 chr10:16859367 RSU1 0.42 4.94 0.41 2.51e-6 Platelet distribution width; TGCT cis rs17030434 0.654 rs10021447 chr4:154646459 A/C cg14289246 chr4:154710475 SFRP2 -0.78 -5.9 -0.47 3.28e-8 Electrocardiographic conduction measures; TGCT cis rs7772486 0.754 rs10872580 chr6:146140281 C/T cg05347473 chr6:146136440 FBXO30 -0.55 -5.21 -0.42 7.69e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.547 rs8075189 chr17:17901946 C/G cg04398451 chr17:18023971 MYO15A -0.31 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT trans rs1814175 0.817 rs7950856 chr11:49976394 C/T cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs12530845 0.943 rs55889179 chr7:135331631 C/T cg23117316 chr7:135346802 PL-5283 -0.5 -4.74 -0.39 5.83e-6 Red blood cell traits; TGCT cis rs1348850 0.914 rs7604673 chr2:178392346 A/G cg22681709 chr2:178499509 PDE11A -0.35 -4.58 -0.38 1.1e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT trans rs2243480 1.000 rs1267820 chr7:66050295 C/G cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs9419702 0.614 rs9419567 chr10:133535149 C/G cg23460707 chr10:133558971 NA 0.42 4.84 0.4 3.8e-6 Survival in rectal cancer; TGCT cis rs4722166 0.630 rs6969258 chr7:22782528 C/T cg26061582 chr7:22766209 IL6 0.57 7.31 0.55 2.85e-11 Lung cancer; TGCT cis rs763121 0.853 rs5750677 chr22:39147715 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.17 0.54 6e-11 Menopause (age at onset); TGCT cis rs2274273 0.682 rs8008134 chr14:55507520 T/C cg01923255 chr14:55878535 KIAA0831 0.56 4.94 0.41 2.51e-6 Protein biomarker; TGCT cis rs2180341 1.000 rs9398838 chr6:127635285 C/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT trans rs1814175 0.817 rs28679516 chr11:50055998 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.5e-6 Prudent dietary pattern; TGCT trans rs6089829 0.855 rs6090203 chr20:61663632 G/A cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2933343 0.649 rs2638845 chr3:128587369 A/G cg11901034 chr3:128598214 ACAD9 -0.64 -6.16 -0.48 9.37e-9 IgG glycosylation; TGCT cis rs7772486 0.875 rs863820 chr6:146347402 C/T cg23711669 chr6:146136114 FBXO30 -0.89 -10.0 -0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs617219 0.591 rs1840805 chr5:78565563 T/A cg23987322 chr5:78407566 BHMT -0.35 -4.57 -0.38 1.15e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11085466 0.948 rs11668453 chr19:21759357 C/A cg23026602 chr19:21646605 NA -0.57 -4.59 -0.38 1.07e-5 Colorectal or endometrial cancer; TGCT cis rs2486288 0.656 rs2413768 chr15:45561984 A/G cg14582100 chr15:45693742 SPATA5L1 -0.44 -5.15 -0.42 1.01e-6 Glomerular filtration rate; TGCT cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg20637647 chr7:64974828 NA 0.93 5.2 0.42 8.11e-7 Diabetic kidney disease; TGCT cis rs56104184 0.779 rs4802513 chr19:49357656 T/A cg17863274 chr19:49399704 TULP2 -0.43 -5.04 -0.41 1.6e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg16414030 chr3:133502952 NA -0.5 -7.01 -0.53 1.39e-10 Iron status biomarkers; TGCT cis rs769267 0.965 rs12460764 chr19:19431963 G/T cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs1799949 0.965 rs8067269 chr17:41235799 C/T cg10047753 chr17:41438598 NA 0.64 5.77 0.46 6.06e-8 Menopause (age at onset); TGCT cis rs28595532 1.000 rs75497896 chr4:119636703 T/C cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.66e-7 Cannabis dependence symptom count; TGCT cis rs28595532 0.920 rs115706007 chr4:119733638 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs6940638 0.615 rs9393801 chr6:27242681 A/G cg11262757 chr6:27280423 POM121L2 0.53 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs66573146 0.901 rs55659111 chr4:7012338 G/T cg01220768 chr4:7056774 TADA2B 0.44 5.07 0.41 1.38e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6912958 0.754 rs7762864 chr6:88236213 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs5750830 0.649 rs5750811 chr22:39793066 G/T cg05872129 chr22:39784769 NA 0.93 10.21 0.68 3.83e-18 Intelligence (multi-trait analysis); TGCT cis rs4555082 0.874 rs2142190 chr14:105719306 G/A cg01266790 chr14:105781312 PACS2 0.55 4.51 0.38 1.49e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs7584330 0.910 rs6713555 chr2:238398182 A/G cg14458575 chr2:238380390 NA -0.44 -5.74 -0.46 6.93e-8 Prostate cancer; TGCT cis rs12142240 0.667 rs45524035 chr1:46862780 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs875971 0.522 rs709604 chr7:65497434 A/G cg18876405 chr7:65276391 NA -0.36 -5.69 -0.45 8.79e-8 Aortic root size; TGCT cis rs2688608 0.905 rs2633300 chr10:75656647 A/C cg19442545 chr10:75533431 FUT11 -0.29 -4.71 -0.39 6.5e-6 Inflammatory bowel disease; TGCT cis rs6988636 1.000 rs28537152 chr8:124189071 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg03806693 chr22:41940476 POLR3H -1.18 -12.3 -0.74 3.18e-23 Vitiligo; TGCT cis rs79149102 0.579 rs3812946 chr15:75288610 G/C cg09165964 chr15:75287851 SCAMP5 -1.06 -5.63 -0.45 1.17e-7 Lung cancer; TGCT cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs6752107 0.936 rs10195395 chr2:234206504 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.71 0.39 6.47e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg25660036 chr4:7070649 GRPEL1 -0.67 -5.91 -0.47 3.15e-8 Monocyte percentage of white cells; TGCT cis rs9902453 0.904 rs12952179 chr17:28412687 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -7.31 -0.55 2.88e-11 Coffee consumption (cups per day); TGCT cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg03396347 chr1:1875803 NA -0.35 -6.4 -0.5 2.95e-9 Body mass index; TGCT cis rs4849845 0.653 rs34874174 chr2:121011980 A/C cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs12549025 0.530 rs11135740 chr8:23367757 A/G cg00472375 chr8:23315376 ENTPD4 -0.62 -5.37 -0.43 3.72e-7 Reticulocyte fraction of red cells; TGCT cis rs2836633 0.929 rs2836610 chr21:40044502 C/T cg12884169 chr21:40033163 ERG 0.43 4.69 0.39 6.99e-6 Coronary artery disease; TGCT cis rs6669072 0.590 rs10922922 chr1:91237055 G/A cg08895590 chr1:91227319 NA 0.32 4.44 0.37 1.98e-5 Cognitive function; TGCT cis rs7192750 0.586 rs4788447 chr16:71874860 C/T cg06353428 chr16:71660113 MARVELD3 0.83 7.37 0.55 2.07e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9733 0.570 rs951281 chr1:150691122 A/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs2288884 0.943 rs11671792 chr19:52581683 A/T cg13540795 chr19:52551618 ZNF432 -0.6 -5.1 -0.42 1.25e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs1018836 0.851 rs2023624 chr8:91618874 T/C cg16814680 chr8:91681699 NA -0.83 -8.73 -0.62 1.46e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10992471 0.630 rs10992322 chr9:95159196 A/G cg14631576 chr9:95140430 CENPP -0.27 -4.56 -0.38 1.22e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs77972916 0.609 rs72790907 chr2:43575195 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.48 -0.37 1.65e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs910316 0.935 rs175448 chr14:75591071 G/A cg11812906 chr14:75593930 NEK9 -0.73 -7.13 -0.54 7.35e-11 Height; TGCT cis rs523522 0.885 rs524735 chr12:121022099 T/C cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs4252435 0.614 rs10270914 chr7:142596224 C/T cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs9486719 1.000 rs12210146 chr6:96903962 A/G cg18709589 chr6:96969512 KIAA0776 0.68 5.05 0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs8141529 0.748 rs132533 chr22:29299571 A/G cg02153584 chr22:29168773 CCDC117 -0.64 -4.91 -0.4 2.87e-6 Lymphocyte counts; TGCT cis rs10089 1.000 rs6887847 chr5:127473807 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.7e-13 Ileal carcinoids; TGCT cis rs909002 0.800 rs3753612 chr1:32082410 C/G cg11573219 chr1:32083031 HCRTR1 -0.43 -5.59 -0.45 1.41e-7 Intelligence (multi-trait analysis); TGCT cis rs763121 0.853 rs3788545 chr22:39065172 A/G cg06022373 chr22:39101656 GTPBP1 0.76 7.52 0.56 9.49e-12 Menopause (age at onset); TGCT cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs1322512 0.677 rs2695255 chr6:152926004 G/A cg03415253 chr6:152958462 SYNE1 -0.55 -5.22 -0.42 7.33e-7 Tonometry; TGCT cis rs8077889 0.826 rs60085355 chr17:41847415 T/C cg26893861 chr17:41843967 DUSP3 1.09 13.68 0.78 1.57e-26 Triglycerides; TGCT trans rs2727020 0.615 rs10128582 chr11:49447424 C/T cg03929089 chr4:120376271 NA -0.77 -9.03 -0.63 2.74e-15 Coronary artery disease; TGCT cis rs7547997 0.858 rs9793907 chr1:158358405 A/G cg07950803 chr1:158223934 CD1A 0.32 4.63 0.38 9.01e-6 QRS duration; TGCT cis rs17433780 0.860 rs61798916 chr1:89493957 G/A cg09516651 chr1:89888402 LOC400759 0.26 4.48 0.37 1.67e-5 Carotid intima media thickness; TGCT cis rs9427116 0.502 rs9427100 chr1:154583762 G/A cg17218026 chr1:154582156 ADAR 0.3 7.54 0.56 8.85e-12 Blood protein levels; TGCT cis rs10504229 0.683 rs56192850 chr8:58135356 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9549367 0.713 rs4907599 chr13:113861441 C/T cg18105134 chr13:113819100 PROZ 0.46 8.57 0.61 3.49e-14 Platelet distribution width; TGCT cis rs17433780 0.897 rs17434151 chr1:89500526 G/T cg09516651 chr1:89888402 LOC400759 0.26 4.48 0.37 1.67e-5 Carotid intima media thickness; TGCT cis rs7582180 0.764 rs1530028 chr2:100927910 A/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.91 -0.4 2.81e-6 Intelligence (multi-trait analysis); TGCT cis rs17108533 0.588 rs12886420 chr14:71301332 A/G cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs2034088 0.833 rs9748016 chr17:410451 G/T cg06217071 chr17:408420 NA 0.35 5.28 0.43 5.59e-7 Hip circumference adjusted for BMI; TGCT cis rs4900538 0.927 rs1190544 chr14:102903398 G/A cg18135206 chr14:102964638 TECPR2 -0.22 -5.31 -0.43 4.81e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2276314 1.000 rs4573997 chr18:33552568 C/T cg05985134 chr18:33552581 C18orf21 0.56 4.93 0.4 2.57e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs6967414 0.579 rs11980762 chr7:6756878 G/A cg09896999 chr7:6746977 ZNF12 -0.59 -6.54 -0.51 1.45e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs7193541 0.673 rs12716769 chr16:74652537 T/C cg01733217 chr16:74700730 RFWD3 0.99 13.69 0.78 1.46e-26 Multiple myeloma; TGCT cis rs826838 1.000 rs826892 chr12:39100790 T/C cg13010199 chr12:38710504 ALG10B -0.59 -4.88 -0.4 3.25e-6 Heart rate; TGCT cis rs13217239 0.646 rs12209886 chr6:26984757 G/A cg15659132 chr6:26577336 NA 0.55 5.55 0.45 1.62e-7 Schizophrenia; TGCT cis rs1532993 0.518 rs7669638 chr4:98640359 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.92 -0.4 2.72e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs7528684 0.816 rs1970265 chr1:157693714 G/C cg17134153 chr1:157670328 FCRL3 -0.26 -4.68 -0.39 7.53e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs372883 0.563 rs1153293 chr21:30691325 C/T cg24692254 chr21:30365293 RNF160 0.51 4.53 0.38 1.39e-5 Pancreatic cancer; TGCT cis rs2637266 1.000 rs7896831 chr10:78366649 A/T cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs9527 0.590 rs11191553 chr10:104851396 G/T cg04362960 chr10:104952993 NT5C2 0.67 5.76 0.46 6.28e-8 Arsenic metabolism; TGCT cis rs950169 0.922 rs17531523 chr15:85132449 C/G cg17173187 chr15:85201210 NMB 0.47 4.99 0.41 1.97e-6 Schizophrenia; TGCT cis rs11711311 1.000 rs2566963 chr3:113531849 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 0.7 6.72 0.52 5.98e-10 IgG glycosylation; TGCT cis rs13242816 1.000 rs2052105 chr7:116187979 T/C cg02799643 chr7:116139180 CAV2 -0.45 -5.55 -0.45 1.66e-7 P wave duration; TGCT cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg20607798 chr8:58055168 NA 0.45 4.62 0.38 9.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs9916302 0.904 rs8070695 chr17:37478062 C/T cg07936489 chr17:37558343 FBXL20 0.62 4.97 0.41 2.16e-6 Glomerular filtration rate (creatinine); TGCT cis rs7246657 0.943 rs7252325 chr19:37930645 A/G cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs12900413 0.523 rs11636525 chr15:90300478 A/G cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2274273 0.653 rs1209087 chr14:55493220 C/T cg01923255 chr14:55878535 KIAA0831 -0.57 -5.01 -0.41 1.82e-6 Protein biomarker; TGCT cis rs78487399 0.808 rs77791126 chr2:43744050 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.78 4.84 0.4 3.8e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7666738 0.791 rs7678564 chr4:99057341 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2354432 0.556 rs66501488 chr1:146853992 T/C cg25205988 chr1:146714368 CHD1L -1.34 -5.79 -0.46 5.52e-8 Mitochondrial DNA levels; TGCT cis rs56104184 0.775 rs73061697 chr19:49400000 C/T cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2933343 1.000 rs1680784 chr3:128644458 A/G cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs3806843 0.966 rs4141841 chr5:140203432 C/T cg19875535 chr5:140030758 IK 0.37 6.16 0.48 9.55e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg05368731 chr17:41323189 NBR1 1.1 11.24 0.71 1.23e-20 Menopause (age at onset); TGCT cis rs9915657 0.840 rs10512582 chr17:70139393 A/C cg06234051 chr17:70120541 SOX9 -0.25 -5.09 -0.42 1.3e-6 Thyroid hormone levels; TGCT cis rs7267979 1.000 rs761025 chr20:25426968 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1903068 0.853 rs12505096 chr4:56006102 C/A cg16572876 chr4:56024045 NA 0.46 5.01 0.41 1.83e-6 Endometriosis; TGCT cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs739496 0.579 rs2285695 chr12:112375308 T/G cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs9911578 0.967 rs686425 chr17:56776730 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs4972806 0.668 rs2072588 chr2:177042930 G/C cg03152288 chr2:177042942 NA 0.65 5.69 0.46 8.63e-8 IgG glycosylation; TGCT cis rs11864453 0.713 rs7190995 chr16:72124157 A/G cg14768367 chr16:72042858 DHODH 0.5 4.8 0.4 4.5e-6 Fibrinogen levels; TGCT cis rs548181 0.611 rs609200 chr11:125383808 G/A cg03464685 chr11:125439445 EI24 -1.63 -11.43 -0.72 4.29e-21 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3733585 0.648 rs35954357 chr4:9978758 G/C cg00071950 chr4:10020882 SLC2A9 0.57 6.68 0.51 7.18e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg20999797 chr1:1681921 NA 0.18 4.61 0.38 9.72e-6 Body mass index; TGCT cis rs3617 0.573 rs3821873 chr3:52913006 C/T cg10802521 chr3:52805072 NEK4 0.56 6.33 0.49 4.09e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs11711311 1.000 rs13070720 chr3:113473754 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs2841277 0.646 rs3742935 chr14:105405599 G/C cg19901468 chr14:105411992 AHNAK2 -0.28 -6.09 -0.48 1.31e-8 Rheumatoid arthritis; TGCT cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg01448562 chr3:133502909 NA -0.26 -4.94 -0.41 2.46e-6 Iron status biomarkers; TGCT cis rs9660992 0.573 rs1172147 chr1:205225457 G/A cg00857998 chr1:205179979 DSTYK 0.51 4.56 0.38 1.21e-5 Mean corpuscular volume;Mean platelet volume; TGCT trans rs1814175 0.702 rs4881644 chr11:49786367 C/T cg11707556 chr5:10655725 ANKRD33B -0.38 -7.76 -0.57 2.75e-12 Height; TGCT cis rs1949733 0.877 rs940133 chr4:8473614 T/C cg11789530 chr4:8429930 ACOX3 0.65 5.61 0.45 1.24e-7 Response to antineoplastic agents; TGCT cis rs3099143 1.000 rs2063542 chr15:77149498 A/G cg21673338 chr15:77095150 SCAPER -0.52 -5.05 -0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs875971 1.000 rs12698523 chr7:65968113 C/G cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs9902453 0.765 rs2250320 chr17:28128657 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.83 -7.95 -0.58 9.99e-13 Coffee consumption (cups per day); TGCT cis rs4727027 0.933 rs757738 chr7:148872351 T/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.69 0.39 7.23e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs17764205 0.777 rs4807434 chr19:3259054 G/T cg18738857 chr19:3606974 TBXA2R -0.74 -4.54 -0.38 1.31e-5 Bipolar disorder and schizophrenia; TGCT cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT trans rs7618501 1.000 rs9859153 chr3:49807085 G/T cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs13188771 0.690 rs72660735 chr5:100886099 A/T cg18665594 chr5:101119420 NA 0.45 4.5 0.37 1.54e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs36051895 0.632 rs117896567 chr9:5141281 C/G cg02405213 chr9:5042618 JAK2 -0.7 -9.44 -0.65 2.91e-16 Pediatric autoimmune diseases; TGCT cis rs12477438 0.520 rs10865029 chr2:99718298 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs2178146 0.535 rs4843944 chr16:86443965 C/G cg11165158 chr16:86613094 FOXL1 0.36 4.71 0.39 6.63e-6 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT cis rs8014204 0.575 rs1045430 chr14:75130235 T/G cg06637938 chr14:75390232 RPS6KL1 0.64 5.88 0.47 3.57e-8 Caffeine consumption; TGCT trans rs7726839 0.561 rs56410216 chr5:583216 C/A cg25482853 chr8:67687455 SGK3 1.07 8.9 0.62 5.55e-15 Obesity-related traits; TGCT cis rs1401999 0.690 rs6773408 chr3:183716609 G/T cg01324343 chr3:183735012 ABCC5 0.74 9.11 0.63 1.82e-15 Anterior chamber depth; TGCT cis rs57590327 0.555 rs3821551 chr3:81710179 A/T cg07356753 chr3:81810745 GBE1 -0.77 -7.03 -0.53 1.22e-10 Extraversion; TGCT cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg22963979 chr7:1858916 MAD1L1 -0.41 -6.6 -0.51 1.06e-9 Bipolar disorder and schizophrenia; TGCT cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg26531700 chr6:26746687 NA 0.52 5.01 0.41 1.8e-6 Intelligence (multi-trait analysis); TGCT cis rs9915657 0.933 rs4793272 chr17:70139257 A/T cg06234051 chr17:70120541 SOX9 -0.25 -4.88 -0.4 3.22e-6 Thyroid hormone levels; TGCT cis rs67311347 1.000 rs11716675 chr3:40485280 G/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs17767294 0.708 rs72848785 chr6:27977603 T/G cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs13256369 1.000 rs12550458 chr8:8567832 G/A cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs7513165 0.551 rs11571077 chr1:204134822 G/A cg12731349 chr1:204159619 KISS1 0.48 4.79 0.4 4.68e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs2380220 0.541 rs9285413 chr6:96023439 G/A cg04719120 chr6:96025338 MANEA 0.73 5.48 0.44 2.31e-7 Behavioural disinhibition (generation interaction); TGCT cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs2836950 0.545 rs2836959 chr21:40623668 T/G cg17971929 chr21:40555470 PSMG1 -0.54 -4.88 -0.4 3.26e-6 Menarche (age at onset); TGCT cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg05985448 chr10:134359359 INPP5A 0.22 4.73 0.39 6e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7226408 0.842 rs62083176 chr18:34324695 G/A cg06757138 chr18:34340585 FHOD3 0.27 4.79 0.4 4.59e-6 Obesity-related traits; TGCT cis rs67478160 0.643 rs3818085 chr14:104215985 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs6964587 1.000 rs12540055 chr7:91707921 A/G cg17063962 chr7:91808500 NA 0.9 9.96 0.67 1.57e-17 Breast cancer; TGCT cis rs9911578 0.967 rs2567892 chr17:56668929 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9372498 0.572 rs62422190 chr6:118909235 A/G cg21191810 chr6:118973309 C6orf204 -0.39 -5.14 -0.42 1.02e-6 Diastolic blood pressure; TGCT cis rs10504229 1.000 rs59843034 chr8:58195756 T/G cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs4727027 0.769 rs10952797 chr7:148816722 A/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.64 0.38 8.88e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs17665859 0.844 rs6980614 chr8:447844 G/A cg17960703 chr8:356704 FBXO25 1.35 5.22 0.42 7.35e-7 Bilirubin levels; TGCT cis rs67311347 0.668 rs73071710 chr3:40288587 A/G cg13683864 chr3:40499215 RPL14 -0.84 -7.91 -0.58 1.2e-12 Renal cell carcinoma; TGCT cis rs7666738 0.830 rs7687315 chr4:98900613 A/G cg17366294 chr4:99064904 C4orf37 0.67 6.83 0.52 3.3e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.600 rs72702224 chr1:154911689 G/A cg06221963 chr1:154839813 KCNN3 -0.7 -11.66 -0.72 1.16e-21 Prostate cancer; TGCT cis rs2486012 1.000 rs61770289 chr1:44363710 T/C cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.697 rs6060912 chr20:30325755 C/A cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs56235845 0.694 rs11748912 chr5:176765395 G/A cg06060754 chr5:176797920 RGS14 0.4 6.33 0.49 3.99e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs2832191 0.933 rs2832236 chr21:30547602 C/T cg24692254 chr21:30365293 RNF160 -0.7 -6.95 -0.53 1.85e-10 Dental caries; TGCT cis rs6087771 0.650 rs6060395 chr20:30219823 G/C cg21427119 chr20:30132790 HM13 -0.3 -5.15 -0.42 9.81e-7 Subcortical brain region volumes;Putamen volume; TGCT cis rs9858542 0.953 rs3811697 chr3:49590770 C/T cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs597539 0.652 rs496616 chr11:68672800 G/C cg21963583 chr11:68658836 MRPL21 0.36 6.03 0.48 1.74e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9788682 1.000 rs7163730 chr15:78814681 A/G cg24631222 chr15:78858424 CHRNA5 0.89 7.68 0.57 4.22e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg21724239 chr8:58056113 NA 0.42 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs2541522 0.600 rs62025788 chr16:10746045 C/T cg21839338 chr16:10912331 FAM18A 0.41 4.67 0.39 7.71e-6 Gut microbiome composition (summer); TGCT cis rs7394190 0.748 rs11000777 chr10:75545063 G/C cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs7312933 0.558 rs11181467 chr12:42765250 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.14 0.42 1.03e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4389656 0.857 rs274719 chr5:6720916 A/G cg10857441 chr5:6722123 POLS -0.22 -4.85 -0.4 3.68e-6 Coronary artery disease; TGCT cis rs1577917 1.000 rs35761942 chr6:86629504 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.36 -0.43 3.86e-7 Response to antipsychotic treatment; TGCT trans rs6089829 0.962 rs2277769 chr20:61666805 C/T cg23505145 chr19:12996616 KLF1 0.84 9.12 0.63 1.68e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs2735413 0.564 rs73580826 chr16:78110889 G/T cg09132178 chr16:78079569 NA 0.37 4.8 0.4 4.4e-6 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs1483890 0.642 rs1843049 chr3:69404078 T/C cg22125112 chr3:69402811 FRMD4B 0.28 4.66 0.39 7.99e-6 Resting heart rate; TGCT cis rs796364 0.806 rs6435041 chr2:200867144 A/G cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT trans rs561341 1.000 rs530715 chr17:30320544 T/G cg20587970 chr11:113659929 NA -1.05 -12.74 -0.75 2.84e-24 Hip circumference adjusted for BMI; TGCT cis rs6570726 0.693 rs450921 chr6:145864260 C/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.962 rs6062778 chr20:61663959 A/G cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7223966 1.000 rs9908044 chr17:61747032 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.05 0.41 1.51e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3125734 0.633 rs4979773 chr10:63967731 G/C cg19640130 chr10:64028056 RTKN2 -0.4 -5.21 -0.42 7.77e-7 Rheumatoid arthritis; TGCT cis rs12477438 0.765 rs6740054 chr2:99576631 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -4.9 -0.4 2.95e-6 Chronic sinus infection; TGCT cis rs9325144 0.560 rs11183046 chr12:38655270 A/T cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg25036284 chr2:26402008 FAM59B -0.63 -5.09 -0.42 1.29e-6 Gut microbiome composition (summer); TGCT cis rs806215 1.000 rs712698 chr7:127249098 C/T cg25922125 chr7:127225783 GCC1 0.59 5.98 0.47 2.21e-8 Type 2 diabetes; TGCT cis rs986417 1.000 rs6573312 chr14:60952536 G/T cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT trans rs208520 0.837 rs208498 chr6:66931560 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.93 -0.67 1.84e-17 Exhaled nitric oxide output; TGCT cis rs881375 0.715 rs11794516 chr9:123640230 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.34 0.43 4.23e-7 Rheumatoid arthritis; TGCT cis rs9341808 0.718 rs9448898 chr6:80845341 T/A cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9549367 0.713 rs4907593 chr13:113830459 C/T cg00898013 chr13:113819073 PROZ 0.55 7.3 0.55 3.03e-11 Platelet distribution width; TGCT cis rs514406 0.683 rs10157120 chr1:53210888 A/G cg16325326 chr1:53192061 ZYG11B 0.89 13.41 0.77 6.6900000000000006e-26 Monocyte count; TGCT cis rs6061231 0.631 rs2427318 chr20:60975727 G/T cg15674680 chr20:60982522 CABLES2 0.57 5.01 0.41 1.86e-6 Colorectal cancer; TGCT cis rs2404602 0.692 rs12910734 chr15:77149931 A/G cg22467129 chr15:76604101 ETFA -0.47 -5.4 -0.44 3.26e-7 Blood metabolite levels; TGCT cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs7954584 0.567 rs11043243 chr12:122356370 G/C cg13699009 chr12:122356056 WDR66 0.29 5.73 0.46 7.13e-8 Mean corpuscular volume; TGCT cis rs67478160 0.583 rs12879612 chr14:104233618 T/A cg26031613 chr14:104095156 KLC1 -0.63 -6.42 -0.5 2.66e-9 Schizophrenia; TGCT cis rs6951245 0.529 rs76001997 chr7:1152615 C/T cg09177884 chr7:1199841 ZFAND2A -0.69 -5.47 -0.44 2.41e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2235642 0.750 rs2974845 chr16:1648162 T/C cg08296037 chr16:1584118 IFT140;TMEM204 -0.28 -4.77 -0.39 5.1e-6 Coronary artery disease; TGCT cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg13607699 chr17:42295918 UBTF -0.59 -5.38 -0.43 3.65e-7 Total body bone mineral density; TGCT cis rs4665809 0.680 rs3955310 chr2:26290828 T/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs1497406 0.744 rs7538966 chr1:16504549 T/C cg20430773 chr1:16534157 ARHGEF19 0.52 5.77 0.46 6.06e-8 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs78456975 0.527 rs7590742 chr2:1575049 A/T cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs1008375 0.868 rs6816286 chr4:17698088 A/G cg10189774 chr4:17578691 LAP3 0.53 4.48 0.37 1.68e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs751728 0.664 rs6929696 chr6:33759290 C/T cg13859433 chr6:33739653 LEMD2 0.34 6.03 0.48 1.76e-8 Crohn's disease; TGCT cis rs35883536 1.000 rs12566507 chr1:101089679 T/A cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.19e-5 Monocyte count; TGCT cis rs7809950 1.000 rs2237676 chr7:107198079 C/A cg23024343 chr7:107201750 COG5 -0.34 -5.26 -0.43 6.08e-7 Coronary artery disease; TGCT cis rs6121246 0.609 rs2377317 chr20:30402502 A/G cg10886678 chr20:30946050 ASXL1 0.56 4.66 0.39 8.07e-6 Mean corpuscular hemoglobin; TGCT cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg07061783 chr6:25882402 NA 0.72 7.4 0.55 1.8e-11 Blood metabolite levels; TGCT cis rs362272 0.524 rs3129334 chr4:3368526 T/C cg06533319 chr4:3265114 C4orf44 -0.25 -5.22 -0.42 7.43e-7 Serum sulfate level; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg04234412 chr22:24373322 LOC391322 -0.91 -10.69 -0.69 2.69e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9611565 0.532 rs4401299 chr22:42156517 A/G cg13695892 chr22:41940480 POLR3H 0.81 7.62 0.56 5.82e-12 Vitiligo; TGCT cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs34172651 0.517 rs11862923 chr16:24767303 G/T cg06028605 chr16:24865363 SLC5A11 0.41 4.58 0.38 1.13e-5 Intelligence (multi-trait analysis); TGCT cis rs903263 1.000 rs2134647 chr1:84678418 C/T cg09664975 chr1:84543551 PRKACB 0.49 4.69 0.39 7.05e-6 Breast cancer (male); TGCT cis rs7260538 0.773 rs2200238 chr19:41527265 G/A cg20630647 chr19:41531805 NA 0.32 5.02 0.41 1.74e-6 DDT metabolite (p,p'-DDE levels); TGCT cis rs2535633 0.631 rs2336670 chr3:52998504 T/G cg05573699 chr3:52720067 GNL3;PBRM1 0.55 5.16 0.42 9.33e-7 Body mass index; TGCT cis rs713587 0.624 rs1550110 chr2:25124563 T/C cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index in non-asthmatics; TGCT cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg09904177 chr6:26538194 HMGN4 0.66 6.33 0.49 3.99e-9 Intelligence (multi-trait analysis); TGCT cis rs74233809 0.534 rs284841 chr10:104550079 G/A cg05855489 chr10:104503620 C10orf26 -0.76 -5.24 -0.43 6.78e-7 Birth weight; TGCT cis rs67311347 0.955 rs11711994 chr3:40391086 T/C cg17264618 chr3:40429014 ENTPD3 0.32 4.59 0.38 1.05e-5 Renal cell carcinoma; TGCT cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg08280861 chr8:58055591 NA 0.36 4.91 0.4 2.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs73099903 0.611 rs10876400 chr12:53436855 T/C cg24505307 chr12:53448429 TENC1 0.36 4.71 0.39 6.56e-6 Systolic blood pressure; TGCT cis rs10256972 0.630 rs10282584 chr7:1081442 C/T cg16145915 chr7:1198662 ZFAND2A -0.44 -5.04 -0.41 1.61e-6 Longevity;Endometriosis; TGCT cis rs6893807 1.000 rs1422191 chr5:87949158 G/A cg24804195 chr5:87968844 LOC645323 0.76 5.64 0.45 1.09e-7 Body mass index; TGCT trans rs2469997 1.000 rs2470016 chr8:120361220 T/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs2072499 0.750 rs7534339 chr1:156156219 A/G cg24450063 chr1:156163899 SLC25A44 1.09 10.01 0.67 1.19e-17 Testicular germ cell tumor; TGCT cis rs9611565 0.506 rs7364221 chr22:41650190 C/A cg13695892 chr22:41940480 POLR3H -0.63 -5.84 -0.46 4.28e-8 Vitiligo; TGCT trans rs3824451 1.000 rs10985825 chr9:101072843 C/T cg11574975 chr1:112058304 ADORA3 -0.42 -6.66 -0.51 7.91e-10 Schizophrenia; TGCT cis rs4722166 0.630 rs2091115 chr7:22810166 G/T cg23864514 chr7:22882512 NA 0.21 4.57 0.38 1.16e-5 Lung cancer; TGCT cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg17554472 chr22:41940697 POLR3H -0.46 -4.74 -0.39 5.83e-6 Vitiligo; TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg11494091 chr17:61959527 GH2 0.6 13.99 0.78 2.88e-27 Prudent dietary pattern; TGCT cis rs2242194 0.844 rs11264295 chr1:154987526 C/T cg06221963 chr1:154839813 KCNN3 -0.51 -6.38 -0.5 3.13e-9 Schizophrenia; TGCT cis rs6840360 0.593 rs6847844 chr4:152693246 C/T cg22705602 chr4:152727874 NA -0.34 -5.9 -0.47 3.24e-8 Intelligence (multi-trait analysis); TGCT cis rs11190604 1.000 rs11816840 chr10:102309220 G/C cg23241863 chr10:102295624 HIF1AN 0.68 5.13 0.42 1.08e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6987853 0.830 rs9643888 chr8:42352007 T/C cg20539142 chr8:42623718 CHRNA6 0.19 4.52 0.38 1.44e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs7044106 0.791 rs10760116 chr9:123494681 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 7.29 0.55 3.24e-11 Hip circumference adjusted for BMI; TGCT cis rs34421088 0.548 rs2618443 chr8:11384556 A/G cg21775007 chr8:11205619 TDH -0.49 -4.59 -0.38 1.09e-5 Neuroticism; TGCT cis rs13256369 0.760 rs7816171 chr8:8575835 T/C cg06671706 chr8:8559999 CLDN23 0.35 4.62 0.38 9.35e-6 Obesity-related traits; TGCT cis rs8056742 0.642 rs34776984 chr16:85037574 C/G cg00229868 chr16:85520891 NA 0.37 4.76 0.39 5.33e-6 Amyotrophic lateral sclerosis; TGCT cis rs7666738 0.830 rs1593573 chr4:98925293 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1865760 0.532 rs1061482 chr6:26086699 G/T cg16482183 chr6:26056742 HIST1H1C 0.57 4.95 0.41 2.39e-6 Height; TGCT cis rs36405 1.000 rs36410 chr14:72356580 C/A cg10066683 chr14:71515513 PCNX 0.24 4.45 0.37 1.87e-5 Yang-deficiency constitution; TGCT cis rs7666738 0.791 rs10022061 chr4:98926821 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs76878669 0.538 rs73489638 chr11:66127639 C/T cg18002602 chr11:66138449 SLC29A2 -0.54 -6.62 -0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs7246657 0.722 rs6508736 chr19:38061757 A/G cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs4919044 0.808 rs2486687 chr10:94778283 T/C cg05127821 chr10:94822908 CYP26C1 -0.77 -5.03 -0.41 1.71e-6 Coronary artery disease; TGCT cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.47 -0.5 2.01e-9 Alzheimer's disease; TGCT cis rs2153535 0.580 rs2327050 chr6:8440630 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs62380364 0.602 rs650702 chr5:88055313 G/A cg22951263 chr5:87985283 NA -0.59 -6.32 -0.49 4.3e-9 Intelligence (multi-trait analysis); TGCT cis rs60843830 1.000 rs62114501 chr2:231741 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.77 7.78 0.57 2.49e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT trans rs8073060 0.544 rs225274 chr17:33971221 C/T cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs425277 0.561 rs925906 chr1:2044054 A/C cg24578937 chr1:2090814 PRKCZ -0.24 -5.78 -0.46 5.78e-8 Height; TGCT cis rs9733 0.628 rs7540874 chr1:150702663 A/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs40363 0.857 rs55989968 chr16:3530658 C/G cg00484396 chr16:3507460 NAT15 0.42 5.03 0.41 1.64e-6 Tuberculosis; TGCT cis rs1008375 1.000 rs6819132 chr4:17689752 G/T cg16339924 chr4:17578868 LAP3 -0.61 -4.81 -0.4 4.33e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs8017423 0.967 rs4904657 chr14:90721600 A/G cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs319204 1.000 rs223100 chr5:146229816 C/G cg25021259 chr5:146258546 PPP2R2B -0.36 -4.57 -0.38 1.17e-5 Schizophrenia; TGCT trans rs13270892 0.556 rs57487396 chr8:20469493 C/T cg26117265 chr10:49674348 ARHGAP22 -0.62 -6.64 -0.51 8.74e-10 Daytime sleep phenotypes; TGCT cis rs9611565 0.592 rs5996038 chr22:41965300 T/C cg06634786 chr22:41940651 POLR3H -0.88 -8.25 -0.6 1.98e-13 Vitiligo; TGCT cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs8180040 0.620 rs2278963 chr3:47054869 G/T cg27129171 chr3:47204927 SETD2 -0.71 -8.32 -0.6 1.32e-13 Colorectal cancer; TGCT cis rs6424115 0.830 rs2502999 chr1:24198321 A/G cg15997130 chr1:24165203 NA 0.86 9.53 0.65 1.76e-16 Immature fraction of reticulocytes; TGCT cis rs6121246 0.908 rs6089094 chr20:30431771 C/T cg13852791 chr20:30311386 BCL2L1 0.76 5.67 0.45 9.7e-8 Mean corpuscular hemoglobin; TGCT cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs763014 0.898 rs8050792 chr16:656033 T/C cg27436995 chr16:743998 FBXL16 -0.45 -4.92 -0.4 2.64e-6 Height; TGCT cis rs6671200 1.000 rs71654417 chr1:95661200 G/A cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs7267979 0.866 rs6138609 chr20:25570985 T/A cg14121845 chr20:25566513 NINL 0.49 5.31 0.43 4.97e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7647973 0.922 rs7620024 chr3:49451691 G/A cg06212747 chr3:49208901 KLHDC8B -0.57 -4.59 -0.38 1.07e-5 Menarche (age at onset); TGCT cis rs3733585 0.579 rs4235356 chr4:10123106 G/C cg00071950 chr4:10020882 SLC2A9 -0.51 -5.29 -0.43 5.31e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13256369 0.708 rs11249886 chr8:8562021 T/A cg18904891 chr8:8559673 CLDN23 0.58 5.34 0.43 4.27e-7 Obesity-related traits; TGCT cis rs2439831 0.867 rs12324572 chr15:43636200 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs3125734 0.633 rs12217669 chr10:63988456 A/G cg19640130 chr10:64028056 RTKN2 0.4 5.08 0.42 1.33e-6 Rheumatoid arthritis; TGCT cis rs3749237 0.964 rs11714957 chr3:49776178 C/T cg10152585 chr3:50297680 NA 0.5 4.65 0.39 8.38e-6 Resting heart rate; TGCT cis rs1056107 0.931 rs7847972 chr9:114976870 C/T cg02332936 chr9:115140584 NA 0.28 4.81 0.4 4.35e-6 Colorectal cancer; TGCT cis rs12286929 0.651 rs12274772 chr11:115098768 C/T cg16269184 chr11:114127960 NA -0.19 -4.45 -0.37 1.91e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11252926 0.563 rs10904173 chr10:462885 G/A cg20256804 chr10:444983 DIP2C 0.23 4.91 0.4 2.83e-6 Psychosis in Alzheimer's disease; TGCT cis rs9457247 1.000 rs2757047 chr6:167374489 C/T cg25258033 chr6:167368657 RNASET2 -0.18 -4.48 -0.37 1.65e-5 Crohn's disease; TGCT trans rs7618501 0.521 rs6774354 chr3:49961780 G/A cg21659725 chr3:3221576 CRBN 0.72 8.08 0.59 4.98e-13 Intelligence (multi-trait analysis); TGCT cis rs3771570 1.000 rs57196672 chr2:242235193 G/A cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs2404602 0.692 rs8037005 chr15:76951109 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs10791323 0.660 rs2156681 chr11:133731644 G/T cg15485101 chr11:133734466 NA 0.37 4.97 0.41 2.19e-6 Childhood ear infection; TGCT cis rs7584330 0.740 rs11891348 chr2:238440449 T/G cg14458575 chr2:238380390 NA 0.34 4.76 0.39 5.32e-6 Prostate cancer; TGCT cis rs597539 0.552 rs6591360 chr11:68718669 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.81 7.37 0.55 2.11e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7246657 0.722 rs1291 chr19:38229378 G/A cg18154014 chr19:37997991 ZNF793 -0.7 -4.94 -0.41 2.47e-6 Coronary artery calcification; TGCT cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg23248424 chr5:179741104 GFPT2 -0.38 -7.0 -0.53 1.41e-10 Height; TGCT cis rs933688 0.938 rs6869048 chr5:90664322 G/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.99 9.32 0.64 5.44e-16 Smoking behavior; TGCT cis rs597539 0.690 rs497149 chr11:68626639 A/T cg21963583 chr11:68658836 MRPL21 0.38 6.24 0.49 6.45e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7255045 0.582 rs4804209 chr19:12985955 G/C cg23899408 chr19:12877188 HOOK2 -0.61 -4.94 -0.41 2.52e-6 Mean corpuscular volume; TGCT cis rs2115630 0.905 rs6496401 chr15:85297793 A/T cg11189052 chr15:85197271 WDR73 -0.63 -6.04 -0.48 1.67e-8 P wave terminal force; TGCT cis rs2404602 0.583 rs4381566 chr15:76589262 A/G cg26408565 chr15:76604113 ETFA -0.45 -6.35 -0.5 3.66e-9 Blood metabolite levels; TGCT cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg17971929 chr21:40555470 PSMG1 0.96 8.86 0.62 6.96e-15 Cognitive function; TGCT cis rs739496 0.694 rs7296651 chr12:112246954 C/G cg10833066 chr12:111807467 FAM109A -0.38 -5.67 -0.45 9.69e-8 Platelet count; TGCT cis rs7226408 0.857 rs11662124 chr18:34728434 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2050392 0.590 rs17547917 chr10:30718303 G/A cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT trans rs66573146 0.831 rs1048009 chr4:6988677 G/A cg07817883 chr1:32538562 TMEM39B 1.29 6.94 0.53 1.97e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs9926296 0.656 rs11861084 chr16:89875710 G/T cg21285383 chr16:89894308 SPIRE2 -0.35 -4.78 -0.39 4.79e-6 Vitiligo; TGCT cis rs6964587 0.869 rs2013334 chr7:91549657 G/A cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs875971 1.000 rs778699 chr7:65868290 G/A cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg06634786 chr22:41940651 POLR3H -0.91 -8.79 -0.62 1.02e-14 Vitiligo; TGCT cis rs2204008 0.837 rs11611861 chr12:38357459 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs6835098 1.000 rs9990666 chr4:174083150 G/T cg08422745 chr4:174089978 GALNT7 -0.93 -10.95 -0.7 6.1e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7267979 0.816 rs374701 chr20:25483616 A/G cg03522245 chr20:25566470 NINL 0.56 5.79 0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6121246 0.909 rs6119651 chr20:30259246 G/T cg18721089 chr20:30220636 NA -0.44 -4.79 -0.39 4.75e-6 Mean corpuscular hemoglobin; TGCT cis rs1538970 0.924 rs11211111 chr1:45908782 C/T cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs3862260 0.509 rs3795662 chr1:120165135 G/T cg16322792 chr1:120165303 ZNF697 0.35 8.4 0.6 8.92e-14 Systemic lupus erythematosus; TGCT cis rs9926296 0.605 rs8046243 chr16:89852133 A/G cg27121462 chr16:89883253 FANCA 0.79 8.57 0.61 3.44e-14 Vitiligo; TGCT cis rs68170813 0.559 rs3823959 chr7:107009379 T/G cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs7208859 0.623 rs9912283 chr17:29110373 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs9677476 0.516 rs11893395 chr2:232022981 G/A cg07929768 chr2:232055508 NA 0.33 5.21 0.42 7.7300000000000005e-07 Food antigen IgG levels; TGCT cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg03806693 chr22:41940476 POLR3H -1.15 -13.26 -0.77 1.52e-25 Vitiligo; TGCT cis rs734999 0.588 rs3748818 chr1:2525660 G/A cg18854424 chr1:2615690 NA 0.46 5.23 0.43 6.92e-7 Ulcerative colitis; TGCT cis rs10779751 1.000 rs12730522 chr1:11284091 G/A cg08854313 chr1:11322531 MTOR 0.92 10.07 0.67 8.5e-18 Body mass index; TGCT cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.7 0.39 6.74e-6 Schizophrenia; TGCT cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg13695892 chr22:41940480 POLR3H 0.93 9.17 0.64 1.31e-15 Vitiligo; TGCT cis rs727505 0.908 rs56155943 chr7:124606346 T/G cg23710748 chr7:124431027 NA -0.26 -4.52 -0.38 1.41e-5 Lewy body disease; TGCT cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs10049985 chr4:99023517 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs151997 0.925 rs28077 chr5:50191946 T/A cg06027927 chr5:50259733 NA 0.47 4.83 0.4 4e-6 Callous-unemotional behaviour; TGCT cis rs1670533 0.697 rs658846 chr4:1084723 G/C cg18657303 chr4:1051139 NA 0.3 4.56 0.38 1.21e-5 Recombination rate (females); TGCT cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg20637647 chr7:64974828 NA 0.84 4.85 0.4 3.63e-6 Diabetic kidney disease; TGCT cis rs10927875 0.864 rs6674071 chr1:16144855 G/C cg14742211 chr1:16348397 CLCNKA -0.2 -4.5 -0.37 1.55e-5 Dilated cardiomyopathy; TGCT cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.03 5.55 0.45 1.62e-7 Alzheimer's disease; TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT trans rs17471911 0.708 rs4132968 chr10:100802473 G/A cg03484267 chr2:207988651 KLF7 -0.52 -6.76 -0.52 4.84e-10 Neuroticism; TGCT cis rs4975616 0.869 rs467095 chr5:1336221 T/C cg07493874 chr5:1342172 CLPTM1L -0.28 -6.88 -0.53 2.69e-10 Lung cancer; TGCT cis rs1008375 0.897 rs3733577 chr4:17649233 T/G cg10189774 chr4:17578691 LAP3 0.58 4.99 0.41 1.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7308116 1.000 rs7297404 chr12:108236164 T/A cg19508191 chr12:109124361 CORO1C -0.45 -4.46 -0.37 1.84e-5 Pelvic organ prolapse (moderate/severe); TGCT cis rs12681287 0.640 rs7460342 chr8:87475137 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs7647973 0.961 rs10154992 chr3:49276077 C/T cg07690219 chr3:49449608 TCTA;RHOA -0.55 -4.48 -0.37 1.68e-5 Menarche (age at onset); TGCT trans rs57221529 0.709 rs4957056 chr5:570105 T/C cg11887960 chr12:57824829 NA 1.11 8.99 0.63 3.47e-15 Lung disease severity in cystic fibrosis; TGCT cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs13191362 1.000 rs55847707 chr6:163003414 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7617773 0.780 rs35190747 chr3:48343290 C/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs860554 0.705 rs832144 chr1:201262477 G/A cg01022117 chr1:201258280 PKP1 0.34 5.01 0.41 1.87e-6 Panic disorder; TGCT cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg01448562 chr3:133502909 NA -0.28 -5.27 -0.43 5.8e-7 Iron status biomarkers; TGCT cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg11301795 chr4:187892539 NA -0.34 -4.9 -0.4 2.97e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs68170813 0.641 rs4730248 chr7:107125939 A/G cg02696742 chr7:106810147 HBP1 -0.66 -5.21 -0.42 7.7e-7 Coronary artery disease; TGCT cis rs6988636 1.000 rs13261021 chr8:124190239 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs7236492 0.627 rs76032846 chr18:77198322 G/A cg15644404 chr18:77186268 NFATC1 -0.36 -4.69 -0.39 7.07e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7914558 1.000 rs10883826 chr10:104830819 A/G cg04362960 chr10:104952993 NT5C2 0.61 5.36 0.43 3.86e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6448317 0.539 rs11931422 chr4:24936925 T/C cg21108841 chr4:24914750 CCDC149 -0.78 -7.24 -0.55 4.15e-11 Heschl's gyrus morphology; TGCT trans rs2727020 0.729 rs10742932 chr11:49173234 T/C cg15704280 chr7:45808275 SEPT13 -0.7 -7.75 -0.57 2.92e-12 Coronary artery disease; TGCT cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg17971929 chr21:40555470 PSMG1 0.98 9.13 0.63 1.6e-15 Cognitive function; TGCT cis rs950776 0.714 rs514743 chr15:78884227 A/T cg06917634 chr15:78832804 PSMA4 -0.65 -5.26 -0.43 6.03e-7 Sudden cardiac arrest; TGCT cis rs1519814 0.654 rs2139438 chr8:121007717 T/C cg22335954 chr8:121166405 COL14A1 -0.37 -4.61 -0.38 9.72e-6 Breast cancer; TGCT cis rs2594989 0.733 rs2616538 chr3:11581076 G/T cg00170343 chr3:11313890 ATG7 0.67 5.24 0.43 6.68e-7 Circulating chemerin levels; TGCT cis rs12540874 0.663 rs1451371 chr7:50553051 T/C cg18232548 chr7:50535776 DDC -0.37 -6.65 -0.51 8.5e-10 Systemic sclerosis; TGCT cis rs763121 0.853 rs5757166 chr22:38995385 G/T cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs7666738 0.924 rs62318940 chr4:99064768 C/T cg17366294 chr4:99064904 C4orf37 0.77 6.93 0.53 2e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs910187 0.605 rs6018320 chr20:45804412 A/G cg27589058 chr20:45804311 EYA2 -0.4 -8.9 -0.62 5.58e-15 Migraine; TGCT cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg16145915 chr7:1198662 ZFAND2A -0.54 -6.95 -0.53 1.86e-10 Longevity;Endometriosis; TGCT cis rs1008375 1.000 rs17507481 chr4:17620066 A/G cg16339924 chr4:17578868 LAP3 0.71 5.79 0.46 5.36e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs763014 0.966 rs4984675 chr16:670117 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.39 -0.6 9.08e-14 Height; TGCT cis rs11077998 0.901 rs3794723 chr17:80529495 G/A cg10255544 chr17:80519551 FOXK2 0.23 4.44 0.37 1.97e-5 Reticulocyte fraction of red cells; TGCT cis rs13242816 1.000 rs35505552 chr7:116104867 T/A cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs769267 0.930 rs1054284 chr19:19616953 T/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.52 -0.38 1.4e-5 Tonsillectomy; TGCT cis rs9303401 0.538 rs35454383 chr17:56475599 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.73 6.69 0.51 7.01e-10 Cognitive test performance; TGCT cis rs5769765 0.778 rs4574208 chr22:50256738 C/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.38 -5.55 -0.45 1.62e-7 Schizophrenia; TGCT cis rs9915657 0.870 rs11077595 chr17:70130030 C/T cg06234051 chr17:70120541 SOX9 -0.25 -4.99 -0.41 2.04e-6 Thyroid hormone levels; TGCT cis rs587847 0.558 rs621096 chr15:37680339 A/T cg16890051 chr15:37175029 LOC145845 -0.37 -4.44 -0.37 1.95e-5 Intraocular pressure; TGCT cis rs1008375 1.000 rs2058339 chr4:17678456 C/T cg16339924 chr4:17578868 LAP3 0.53 4.63 0.38 9.27e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9300255 0.602 rs2851450 chr12:123703501 C/T cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs908922 0.584 rs10888500 chr1:152532749 G/A cg20991723 chr1:152506922 NA 0.44 5.99 0.47 2.14e-8 Hair morphology; TGCT cis rs453301 0.686 rs4840389 chr8:8884503 G/C cg00184457 chr8:8946301 NA -0.27 -4.85 -0.4 3.69e-6 Joint mobility (Beighton score); TGCT cis rs7829975 0.684 rs488904 chr8:8587571 T/G cg15556689 chr8:8085844 FLJ10661 -0.63 -5.46 -0.44 2.44e-7 Mood instability; TGCT cis rs644799 0.648 rs1016031 chr11:95473365 C/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.6 -5.7 -0.46 8.3e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10501293 0.746 rs7943869 chr11:43006238 T/C cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.2e-9 Cognitive performance; TGCT cis rs6594499 0.903 rs1438672 chr5:110467753 G/A cg04022379 chr5:110408740 TSLP 0.45 4.76 0.39 5.33e-6 Allergic disease (asthma, hay fever or eczema); TGCT trans rs4942242 1.000 rs4942242 chr13:44217064 A/G cg19169023 chr15:41853346 TYRO3 0.33 6.68 0.51 7.18e-10 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs60154123 0.505 rs7540237 chr1:210053325 C/T cg23283495 chr1:209979779 IRF6 0.63 4.69 0.39 7.02e-6 Coronary artery disease; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg27535305 chr1:53392650 SCP2 -0.24 -4.69 -0.39 6.96e-6 Monocyte count; TGCT cis rs909674 0.865 rs5757684 chr22:39851584 G/A cg02038168 chr22:39784481 NA -0.68 -5.2 -0.42 8.03e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.85 -8.89 -0.62 6.06e-15 Intelligence (multi-trait analysis); TGCT cis rs9913156 0.696 rs72835620 chr17:4558128 G/A cg19197139 chr17:4613644 ARRB2 0.86 7.9 0.58 1.32e-12 Lymphocyte counts; TGCT cis rs6450176 1.000 rs7707547 chr5:53295737 A/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7611238 0.583 rs9848473 chr3:195122930 T/G cg27323046 chr3:195102265 ACAP2 0.39 5.18 0.42 8.86e-7 Body mass index; TGCT cis rs950027 0.787 rs2433616 chr15:45728599 A/G cg14582100 chr15:45693742 SPATA5L1 0.39 4.93 0.4 2.61e-6 Response to fenofibrate (adiponectin levels); TGCT cis rs4499344 0.531 rs259247 chr19:33147657 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.77 7.61 0.56 6.04e-12 Mean platelet volume; TGCT cis rs7120173 0.693 rs12799198 chr11:116801422 C/T cg20847018 chr11:116580245 NA 0.24 4.6 0.38 1.01e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs8177253 0.828 rs8177259 chr3:133480388 T/C cg08048268 chr3:133502702 NA -0.65 -9.84 -0.66 3.1e-17 Iron status biomarkers; TGCT cis rs12477438 0.520 rs6542865 chr2:99764521 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs614226 1.000 rs1167726 chr12:120967364 A/C cg10072921 chr12:121022843 NA 0.44 4.66 0.39 8.13e-6 Type 1 diabetes nephropathy; TGCT cis rs7937890 0.967 rs963212 chr11:14324732 A/G cg19336497 chr11:14380999 RRAS2 0.31 4.93 0.4 2.59e-6 Mitochondrial DNA levels; TGCT cis rs11785693 0.862 rs17435605 chr8:4987302 A/G cg26367366 chr8:4980734 NA 0.58 4.51 0.38 1.48e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs4629710 0.592 rs11759926 chr6:131571269 G/T cg12606694 chr6:131520996 AKAP7 0.41 4.86 0.4 3.55e-6 Multiple myeloma (IgH translocation); TGCT cis rs8014204 0.566 rs752857 chr14:75130944 C/T cg06637938 chr14:75390232 RPS6KL1 0.57 5.17 0.42 9.18e-7 Caffeine consumption; TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg01802117 chr1:53393560 SCP2 -0.41 -4.8 -0.4 4.39e-6 Monocyte count; TGCT cis rs3091242 1.000 rs646867 chr1:25709258 A/C cg00786635 chr1:25594202 NA 0.52 5.33 0.43 4.43e-7 Erythrocyte sedimentation rate; TGCT cis rs713587 0.571 rs2918630 chr2:25314186 A/G cg01884057 chr2:25150051 NA -0.25 -4.8 -0.4 4.42e-6 Body mass index in non-asthmatics; TGCT cis rs7044106 0.791 rs10739572 chr9:123489815 C/T cg14255062 chr9:123606675 PSMD5;LOC253039 0.2 4.77 0.39 5.13e-6 Hip circumference adjusted for BMI; TGCT cis rs17152411 0.895 rs7906592 chr10:126627861 C/G cg07906193 chr10:126599966 NA 0.41 5.14 0.42 1.05e-6 Height; TGCT cis rs3924048 0.574 rs11588028 chr1:12612385 T/C cg00291366 chr1:12616550 NA 0.32 4.87 0.4 3.34e-6 Optic cup area; TGCT cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.61 -0.38 1.01e-5 Schizophrenia; TGCT cis rs3820928 0.874 rs10210997 chr2:227859108 C/T cg11843606 chr2:227700838 RHBDD1 -0.5 -4.47 -0.37 1.77e-5 Pulmonary function; TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs17376456 1.000 rs67150649 chr5:93292377 A/G cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs7552404 0.731 rs1770887 chr1:76401812 A/G cg03433033 chr1:76189801 ACADM -0.78 -7.85 -0.58 1.69e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2046867 0.818 rs7637138 chr3:72910886 A/G cg25664220 chr3:72788482 NA -0.55 -7.37 -0.55 2.12e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7586879 0.789 rs7560156 chr2:25124794 T/C cg01884057 chr2:25150051 NA 0.27 4.81 0.4 4.36e-6 Body mass index; TGCT cis rs12220238 0.915 rs11001021 chr10:76139657 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.88 5.39 0.44 3.41e-7 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1552244 0.816 rs17050701 chr3:10041554 A/G cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs7914558 0.966 rs10748837 chr10:104880236 T/C cg04362960 chr10:104952993 NT5C2 0.63 5.64 0.45 1.07e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs427394 0.659 rs175594 chr5:6729885 T/G cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs1075232 1.000 rs16956838 chr15:31819695 C/G cg01030201 chr15:31746330 NA -0.88 -5.07 -0.41 1.44e-6 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs7267979 0.738 rs2892409 chr20:25638138 C/T cg13486641 chr20:25479848 NINL -0.15 -4.54 -0.38 1.32e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7945705 0.747 rs1980428 chr11:9010497 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.6 0.38 1.04e-5 Hemoglobin concentration; TGCT cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.61 -6.12 -0.48 1.16e-8 Bipolar disorder; TGCT cis rs9814567 1.000 rs6782563 chr3:134295959 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.91 8.83 0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2243480 1.000 rs778729 chr7:65824419 T/C cg07424592 chr7:64974309 NA 1.27 7.28 0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs875971 0.862 rs7803416 chr7:65954199 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs3096299 0.933 rs28608022 chr16:89454292 C/T cg06640241 chr16:89574553 SPG7 0.64 6.3 0.49 4.76e-9 Multiple myeloma (IgH translocation); TGCT cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg20637647 chr7:64974828 NA 0.97 5.37 0.43 3.82e-7 Diabetic kidney disease; TGCT cis rs9942416 0.592 rs10462521 chr5:74985867 T/C cg19683494 chr5:74908142 NA 0.59 6.26 0.49 5.62e-9 Age-related disease endophenotypes; TGCT cis rs394563 0.559 rs13219868 chr6:149686518 T/G cg16235748 chr6:149772707 ZC3H12D 0.44 5.03 0.41 1.66e-6 Dupuytren's disease; TGCT cis rs1005277 0.579 rs2474584 chr10:38416389 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7582180 0.625 rs12612755 chr2:100906061 T/C cg14675211 chr2:100938903 LONRF2 0.45 4.52 0.38 1.4e-5 Intelligence (multi-trait analysis); TGCT cis rs7258465 1.000 rs2007981 chr19:18567555 C/A cg06462663 chr19:18546047 ISYNA1 0.2 4.51 0.38 1.5e-5 Breast cancer; TGCT cis rs9581857 0.579 rs7332104 chr13:27957831 C/G cg22138327 chr13:27999177 GTF3A -0.65 -4.45 -0.37 1.9e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6938 0.662 rs12487 chr15:75136694 A/G cg09165964 chr15:75287851 SCAMP5 0.51 4.65 0.39 8.52e-6 Breast cancer; TGCT cis rs4595586 0.546 rs11169801 chr12:39241429 G/A cg13010199 chr12:38710504 ALG10B 0.6 4.72 0.39 6.26e-6 Morning vs. evening chronotype; TGCT cis rs9527 0.615 rs2152915 chr10:104691732 A/T cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg01238044 chr22:24384105 GSTT1 -0.49 -4.49 -0.37 1.63e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.19 -0.54 5.48e-11 Prostate cancer; TGCT cis rs2404602 0.583 rs2469542 chr15:76557476 A/G cg26408565 chr15:76604113 ETFA 0.47 6.51 0.5 1.65e-9 Blood metabolite levels; TGCT cis rs10504229 0.683 rs72649187 chr8:58108320 A/G cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2688608 0.653 rs12775558 chr10:75570868 G/A cg15838173 chr10:75533400 FUT11 -0.3 -4.83 -0.4 4.02e-6 Inflammatory bowel disease; TGCT cis rs6424115 1.000 rs4237 chr1:24114129 C/T cg15997130 chr1:24165203 NA 0.89 10.32 0.68 2.11e-18 Immature fraction of reticulocytes; TGCT cis rs6912958 0.781 rs4707379 chr6:88310623 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -5.2 -0.42 7.9e-7 Monocyte percentage of white cells; TGCT cis rs2013441 1.000 rs8079701 chr17:20216565 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs3771570 0.901 rs6757876 chr2:242245570 T/C cg21155796 chr2:242212141 HDLBP 0.88 6.39 0.5 3.1e-9 Prostate cancer; TGCT cis rs11098499 0.691 rs10010355 chr4:120261043 A/G cg09307838 chr4:120376055 NA 0.55 5.36 0.43 3.98e-7 Corneal astigmatism; TGCT cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg01411255 chr17:61851458 DDX42;CCDC47 1.1 12.81 0.75 1.93e-24 Height; TGCT cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg23758822 chr17:41437982 NA 0.73 6.99 0.53 1.52e-10 Menopause (age at onset); TGCT cis rs7552404 0.727 rs12122939 chr1:76276353 T/C cg03433033 chr1:76189801 ACADM 0.66 6.88 0.53 2.57e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg05368731 chr17:41323189 NBR1 1.16 13.52 0.77 3.79e-26 Menopause (age at onset); TGCT cis rs669446 0.591 rs574736 chr1:44106266 C/T cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs2404602 1.000 rs12443137 chr15:76840832 G/T cg22467129 chr15:76604101 ETFA -0.49 -5.48 -0.44 2.24e-7 Blood metabolite levels; TGCT cis rs56104184 0.775 rs73061692 chr19:49399676 T/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6831352 0.918 rs2851253 chr4:100043505 G/T cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.64e-6 Alcohol dependence; TGCT cis rs524281 0.692 rs2302884 chr11:65824084 C/T cg00563793 chr11:65837595 PACS1 0.53 4.66 0.39 8e-6 Electroencephalogram traits; TGCT cis rs3771570 1.000 rs6752050 chr2:242228780 T/C cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs60843830 1.000 rs3828165 chr2:220889 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.77 7.44 0.56 1.47e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs12220238 0.915 rs11000988 chr10:76073723 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.28 0.49 5.18e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs66573146 0.831 rs6851488 chr4:6987412 C/T cg05069807 chr4:6945702 TBC1D14 0.3 4.83 0.4 3.98e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7726839 0.540 rs72703080 chr5:595238 A/G cg20362242 chr5:692897 TPPP 0.53 4.62 0.38 9.42e-6 Obesity-related traits; TGCT cis rs4730250 0.707 rs257385 chr7:106807448 T/C cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.6e-8 Osteoarthritis; TGCT cis rs66573146 1.000 rs55688389 chr4:7030689 C/G cg05069807 chr4:6945702 TBC1D14 0.4 5.33 0.43 4.49e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs12541335 0.639 rs7834182 chr8:22163112 G/A cg18135555 chr8:22132992 PIWIL2 0.3 6.2 0.49 7.71e-9 Hypertriglyceridemia; TGCT cis rs6545883 0.929 rs9679557 chr2:61709349 C/A cg15711740 chr2:61764176 XPO1 -0.56 -4.97 -0.41 2.13e-6 Tuberculosis; TGCT cis rs853679 0.527 rs853693 chr6:28282648 C/T cg18815343 chr6:28367644 ZSCAN12 -0.46 -4.95 -0.41 2.41e-6 Depression; TGCT cis rs931127 0.658 rs7926512 chr11:65464487 T/A cg27068330 chr11:65405492 SIPA1 -0.66 -6.59 -0.51 1.13e-9 Systemic lupus erythematosus; TGCT cis rs4891159 0.536 rs690392 chr18:74152618 G/A cg24786174 chr18:74118243 ZNF516 0.66 11.85 0.73 3.89e-22 Longevity; TGCT cis rs1568889 0.592 rs11828877 chr11:28384030 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.7 5.27 0.43 5.86e-7 Bipolar disorder; TGCT cis rs6906287 0.625 rs7757892 chr6:118844221 G/A cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT trans rs7698623 0.850 rs4147244 chr4:88779168 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs2050392 0.931 rs2265189 chr10:30689316 C/T cg13289132 chr10:30722225 MAP3K8 0.36 4.45 0.37 1.92e-5 Inflammatory bowel disease; TGCT cis rs9911578 1.000 rs2009948 chr17:56611920 A/C cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.859 rs12599207 chr16:1606445 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.8 -0.4 4.41e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs880472 chr4:98922595 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs11107903 1.000 rs11107900 chr12:95505052 C/T cg10621809 chr12:95840313 NA 0.7 4.61 0.38 9.89e-6 Coronary artery disease; TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT trans rs9383153 1.000 rs2237223 chr6:16329741 G/A cg22767166 chr8:49833685 SNAI2 0.92 6.66 0.51 7.98e-10 Gambling; TGCT cis rs7829975 0.682 rs7013471 chr8:8687325 A/G cg15556689 chr8:8085844 FLJ10661 -0.66 -5.86 -0.47 3.91e-8 Mood instability; TGCT cis rs916888 0.773 rs199534 chr17:44824213 T/G cg16520312 chr17:43971471 MAPT;LOC100128977 -0.64 -5.6 -0.45 1.32e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg20637647 chr7:64974828 NA 0.99 5.38 0.44 3.53e-7 Diabetic kidney disease; TGCT cis rs12765878 0.513 rs10883922 chr10:105595430 C/G cg11005552 chr10:105648138 OBFC1 -0.39 -6.06 -0.48 1.49e-8 Coronary artery disease; TGCT cis rs17376456 0.877 rs12374463 chr5:93483569 C/G cg21475434 chr5:93447410 FAM172A 0.63 4.67 0.39 7.67e-6 Diabetic retinopathy; TGCT cis rs12971120 0.891 rs2278159 chr18:72178161 T/C cg26446133 chr18:72167187 CNDP2 -0.35 -5.89 -0.47 3.42e-8 Refractive error; TGCT cis rs9302065 0.681 rs59108692 chr13:95962424 C/A cg24476569 chr13:95954382 ABCC4 -0.44 -6.35 -0.5 3.64e-9 Blood metabolite levels; TGCT cis rs7691216 0.514 rs7694080 chr4:86134264 C/T cg05688618 chr4:86699962 ARHGAP24 -0.35 -4.51 -0.38 1.5e-5 IgG glycosylation; TGCT cis rs12134245 0.776 rs13447526 chr1:91983174 A/G cg25838465 chr1:92012736 NA 0.44 7.01 0.53 1.34e-10 Breast cancer; TGCT cis rs2562456 0.793 rs2562428 chr19:21625454 G/C cg01304269 chr19:21688519 ZNF429 -0.58 -4.66 -0.39 8e-6 Pain; TGCT cis rs3617 0.625 rs2071042 chr3:52864584 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.53 0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7246657 0.550 rs9941475 chr19:38064517 C/T cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs7914558 0.966 rs10748835 chr10:104660256 C/T cg15744005 chr10:104629667 AS3MT -0.39 -5.04 -0.41 1.6e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6138458 0.887 rs227622 chr20:24910597 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs4805272 0.962 rs1363327 chr19:29325571 A/C cg15000279 chr19:29285009 NA -0.52 -5.64 -0.45 1.07e-7 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs10986311 0.683 rs2150237 chr9:127082375 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.83 -0.4 3.87e-6 Vitiligo; TGCT cis rs7119038 0.509 rs11216960 chr11:118577873 G/A cg19308663 chr11:118741387 NA 0.24 4.5 0.37 1.54e-5 Sjögren's syndrome; TGCT cis rs12477438 0.520 rs11678456 chr2:99708237 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs9383153 0.793 rs2016498 chr6:16344914 C/T cg20052079 chr6:15504923 JARID2 0.85 5.13 0.42 1.09e-6 Gambling; TGCT cis rs6546537 1.000 rs4852892 chr2:69866769 T/A cg10773587 chr2:69614142 GFPT1 -0.71 -6.21 -0.49 7.48e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs694419 0.602 rs12150719 chr18:60180026 A/C cg13506219 chr18:60193840 ZCCHC2 -0.55 -4.93 -0.4 2.58e-6 Serum albumin level; TGCT cis rs3008870 0.755 rs2815355 chr1:67485034 A/G cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.37 0.6 1.04e-13 Lymphocyte percentage of white cells; TGCT cis rs10131894 0.635 rs174997 chr14:75434806 G/A cg08847533 chr14:75593920 NEK9 -0.66 -6.31 -0.49 4.51e-9 Coronary artery disease; TGCT cis rs2440129 1.000 rs2920420 chr17:6906944 A/G cg05215272 chr17:6899095 ALOX12 0.43 4.45 0.37 1.86e-5 Tonsillectomy; TGCT cis rs2120019 1.000 rs2120019 chr15:75334184 T/C cg09165964 chr15:75287851 SCAMP5 -1.14 -10.22 -0.68 3.76e-18 Blood trace element (Zn levels); TGCT cis rs7786808 0.579 rs55701656 chr7:158188812 G/A cg01191920 chr7:158217561 PTPRN2 -0.36 -5.38 -0.43 3.65e-7 Obesity-related traits; TGCT cis rs1008375 0.932 rs7697329 chr4:17657853 C/A cg16339924 chr4:17578868 LAP3 0.66 5.52 0.44 1.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg18722847 chr3:44754129 ZNF502 -0.4 -4.49 -0.37 1.58e-5 Depressive symptoms; TGCT cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg10802521 chr3:52805072 NEK4 -0.74 -9.02 -0.63 2.87e-15 Bipolar disorder; TGCT cis rs74181299 0.806 rs1009360 chr2:65276049 T/C cg05010058 chr2:65284262 CEP68 0.39 4.48 0.37 1.67e-5 Pulse pressure; TGCT cis rs1552244 0.688 rs9875667 chr3:10180041 T/C cg00149659 chr3:10157352 C3orf10 0.77 5.61 0.45 1.25e-7 Alzheimer's disease; TGCT cis rs1982963 0.950 rs2645750 chr14:52502792 C/A cg10843707 chr14:52510701 NID2 -0.42 -6.47 -0.5 2.07e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9810089 0.708 rs711977 chr3:136227387 G/A cg12473912 chr3:136751656 NA 0.34 4.81 0.4 4.29e-6 Gestational age at birth (child effect); TGCT cis rs10032931 1.000 rs10032931 chr4:96458433 T/C cg03008707 chr4:96468962 UNC5C -0.4 -5.39 -0.44 3.44e-7 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs3820068 0.603 rs59558854 chr1:15971399 T/G cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.25e-13 Systolic blood pressure; TGCT trans rs4332037 0.624 rs73046339 chr7:1889300 G/A cg25206134 chr2:45395956 NA 0.95 8.08 0.59 4.81e-13 Bipolar disorder; TGCT cis rs7264396 0.635 rs6058382 chr20:34553948 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs12148488 0.763 rs12898551 chr15:75297907 C/G cg10253484 chr15:75165896 SCAMP2 -0.61 -5.24 -0.43 6.6e-7 Caffeine consumption; TGCT cis rs938554 0.513 rs11943372 chr4:9999346 T/A cg00071950 chr4:10020882 SLC2A9 0.56 5.13 0.42 1.09e-6 Blood metabolite levels; TGCT cis rs9443189 0.617 rs2842570 chr6:76415274 A/T cg01950844 chr6:76311363 SENP6 0.74 4.85 0.4 3.62e-6 Prostate cancer; TGCT cis rs9399135 0.967 rs6910530 chr6:135332770 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs2836974 0.644 rs2836986 chr21:40702136 A/C cg06238570 chr21:40685208 BRWD1 -0.82 -8.86 -0.62 7.17e-15 Cognitive function; TGCT cis rs554111 0.656 rs17450586 chr1:21254593 T/G cg01072550 chr1:21505969 NA 0.35 5.33 0.43 4.44e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs9816226 0.590 rs872602 chr3:185826028 A/G cg00760338 chr3:185826511 ETV5 0.71 6.24 0.49 6.28e-9 Obesity;Body mass index; TGCT cis rs16854884 1.000 rs34730687 chr3:143813193 A/G cg06585982 chr3:143692056 C3orf58 0.67 4.44 0.37 1.95e-5 Economic and political preferences (feminism/equality); TGCT cis rs7296418 0.961 rs1790122 chr12:123606739 G/A cg13010344 chr12:123464640 ARL6IP4 -0.31 -4.44 -0.37 2e-5 Platelet count; TGCT cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg02725872 chr8:58115012 NA -0.37 -4.57 -0.38 1.19e-5 Developmental language disorder (linguistic errors); TGCT cis rs1552244 0.816 rs56271597 chr3:10042790 C/T cg00149659 chr3:10157352 C3orf10 0.78 4.99 0.41 2.04e-6 Alzheimer's disease; TGCT cis rs9368481 0.761 rs3931464 chr6:26939856 C/A cg07220782 chr6:26987966 LOC100270746;C6orf41 0.46 5.0 0.41 1.88e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12903563 0.505 rs12898861 chr15:77983802 A/G cg25212270 chr15:78015279 NA 0.23 4.48 0.37 1.67e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs17601876 0.843 rs28518777 chr15:51553507 G/A cg19946085 chr15:51559439 CYP19A1 -0.31 -4.75 -0.39 5.44e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs80282103 0.618 rs11816485 chr10:1147974 T/C cg18964960 chr10:1102726 WDR37 0.98 4.57 0.38 1.15e-5 Glomerular filtration rate (creatinine); TGCT cis rs7017914 0.967 rs34042354 chr8:71730961 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs1865760 0.534 rs72834629 chr6:26023032 C/T cg17691542 chr6:26056736 HIST1H1C 0.7 5.34 0.43 4.28e-7 Height; TGCT cis rs208520 0.690 rs1304672 chr6:66847973 A/G cg07460842 chr6:66804631 NA 0.89 8.59 0.61 3.06e-14 Exhaled nitric oxide output; TGCT cis rs9859260 0.710 rs419068 chr3:195782176 C/T cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs1538970 0.962 rs9429075 chr1:45818421 G/A cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs7255045 0.752 rs2242514 chr19:12982798 C/T cg23899408 chr19:12877188 HOOK2 0.59 4.86 0.4 3.45e-6 Mean corpuscular volume; TGCT cis rs9583531 0.574 rs7319459 chr13:111352408 T/C cg24331049 chr13:111365604 ING1 -0.82 -7.94 -0.58 1.04e-12 Coronary artery disease; TGCT cis rs9611565 0.592 rs4481089 chr22:41980892 T/C cg13695892 chr22:41940480 POLR3H -0.83 -7.82 -0.57 1.94e-12 Vitiligo; TGCT cis rs12579753 0.917 rs7132732 chr12:82206053 C/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs9303401 0.612 rs2526370 chr17:56487636 G/C cg12560992 chr17:57184187 TRIM37 0.62 6.56 0.51 1.32e-9 Cognitive test performance; TGCT cis rs875971 1.000 rs6963646 chr7:65685767 T/C cg11764359 chr7:65958608 NA -0.61 -5.52 -0.44 1.93e-7 Aortic root size; TGCT cis rs28595532 0.541 rs114463740 chr4:119763329 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs11971779 0.711 rs6961204 chr7:139047399 T/G cg07862535 chr7:139043722 LUC7L2 0.75 5.43 0.44 2.86e-7 Diisocyanate-induced asthma; TGCT cis rs67311347 0.713 rs4974018 chr3:40307419 G/A cg13683864 chr3:40499215 RPL14 -0.87 -8.51 -0.61 4.77e-14 Renal cell carcinoma; TGCT cis rs9611565 0.559 rs12483860 chr22:41961916 C/T cg06481639 chr22:41940642 POLR3H -0.67 -5.71 -0.46 7.87e-8 Vitiligo; TGCT cis rs9443645 0.901 rs1984195 chr6:79657391 G/A cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs9368551 chr6:28061792 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs2046867 0.628 rs7356055 chr3:72912878 A/C cg25664220 chr3:72788482 NA -0.44 -5.71 -0.46 7.76e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs35000415 0.938 rs34725944 chr7:128641653 T/C cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs2996428 0.667 rs17412654 chr1:3758493 T/C cg13057898 chr1:3703894 LRRC47 0.21 4.62 0.38 9.46e-6 Red cell distribution width; TGCT cis rs854765 0.583 rs4244602 chr17:17841456 A/G cg09796270 chr17:17721594 SREBF1 0.28 5.66 0.45 9.89e-8 Total body bone mineral density; TGCT trans rs61931739 0.500 rs11053193 chr12:34438838 G/T cg26384229 chr12:38710491 ALG10B 0.73 6.93 0.53 2e-10 Morning vs. evening chronotype; TGCT cis rs1887596 0.554 rs1888547 chr13:27103257 T/C cg01312412 chr13:27282625 NA -0.26 -4.44 -0.37 1.96e-5 Facial morphology (factor 3, length of philtrum); TGCT cis rs3008870 1.000 rs2755240 chr1:67477339 T/G cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.37 0.71 5.7e-21 Lymphocyte percentage of white cells; TGCT cis rs7666738 0.830 rs9998682 chr4:98939009 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12780845 0.540 rs3780961 chr10:17195132 G/A cg01003015 chr10:17271136 VIM -0.52 -4.78 -0.39 4.89e-6 Homocysteine levels; TGCT cis rs137603 0.644 rs137621 chr22:39710244 G/A cg17798944 chr22:39715225 SNORD43;RPL3 -0.68 -7.19 -0.54 5.24e-11 Primary biliary cholangitis; TGCT cis rs35306767 0.951 rs11253530 chr10:993729 T/C cg20503657 chr10:835505 NA 0.63 8.32 0.6 1.37e-13 Eosinophil percentage of granulocytes; TGCT cis rs2836950 0.509 rs4816618 chr21:40599529 G/A cg17971929 chr21:40555470 PSMG1 -0.51 -4.64 -0.38 8.88e-6 Menarche (age at onset); TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg19626725 chr5:178986131 RUFY1 0.51 6.7 0.52 6.43e-10 Lung cancer; TGCT cis rs2354432 0.607 rs10900350 chr1:146828017 T/G cg25205988 chr1:146714368 CHD1L 1.36 6.23 0.49 6.77e-9 Mitochondrial DNA levels; TGCT cis rs7833790 0.636 rs12544174 chr8:82731477 G/A cg17211192 chr8:82754475 SNX16 -0.95 -8.83 -0.62 8.45e-15 Diastolic blood pressure; TGCT cis rs11662586 0.517 rs7230837 chr18:77695384 A/T cg20368463 chr18:77673604 PQLC1 0.56 6.81 0.52 3.71e-10 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs4499344 0.531 rs863905 chr19:33146403 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.76 7.52 0.56 9.49e-12 Mean platelet volume; TGCT cis rs250677 0.652 rs250675 chr5:148438565 A/C cg23229984 chr5:148520753 ABLIM3 -0.26 -5.79 -0.46 5.31e-8 Breast cancer; TGCT cis rs7666738 0.830 rs113999196 chr4:99041961 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7568458 0.811 rs3755015 chr2:85764041 G/A cg02493740 chr2:85810744 VAMP5 -0.29 -5.47 -0.44 2.35e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs28595532 0.920 rs114667001 chr4:119786974 T/C cg21605333 chr4:119757512 SEC24D 1.55 8.04 0.59 6.15e-13 Cannabis dependence symptom count; TGCT cis rs11030122 0.702 rs10835312 chr11:3950253 G/A cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg12310025 chr6:25882481 NA 0.51 4.59 0.38 1.06e-5 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs596277 chr11:95566886 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 7.92 0.58 1.12e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs877529 0.605 rs79505 chr22:39551567 A/G cg18708252 chr22:39545030 CBX7 -0.39 -5.82 -0.46 4.66e-8 Multiple myeloma; TGCT cis rs950027 0.620 rs1719245 chr15:45623782 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 6.17 0.48 8.68e-9 Response to fenofibrate (adiponectin levels); TGCT cis rs2180341 0.960 rs6913424 chr6:127707010 A/C cg24812749 chr6:127587940 RNF146 0.93 7.25 0.55 3.85e-11 Breast cancer; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg08859206 chr1:53392774 SCP2 -0.41 -6.57 -0.51 1.24e-9 Monocyte count; TGCT trans rs877282 0.891 rs12767062 chr10:797961 C/T cg22713356 chr15:30763199 NA 1.16 10.18 0.67 4.53e-18 Uric acid levels; TGCT cis rs10754283 0.967 rs10737708 chr1:90119804 A/G cg03145924 chr1:90228473 NA -0.4 -4.52 -0.38 1.4e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7681440 0.904 rs7698219 chr4:90771351 C/A cg26578617 chr4:90757533 SNCA -0.46 -4.73 -0.39 6.01e-6 Dementia with Lewy bodies; TGCT cis rs7666738 0.830 rs11721726 chr4:98996314 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 1.000 rs2079703 chr17:56603978 G/A cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs896854 0.548 rs574183 chr8:95973816 A/G cg16049864 chr8:95962084 TP53INP1 0.65 7.91 0.58 1.23e-12 Type 2 diabetes; TGCT cis rs3733585 0.673 rs4292332 chr4:9953830 C/A cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4268898 0.760 rs7597919 chr2:24563646 A/G cg02683114 chr2:24398427 C2orf84 0.2 4.92 0.4 2.65e-6 Asthma; TGCT cis rs11098499 0.863 rs7699064 chr4:120428309 A/G cg09307838 chr4:120376055 NA -0.71 -6.91 -0.53 2.24e-10 Corneal astigmatism; TGCT trans rs7613875 0.620 rs34312088 chr3:50032133 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.83 8.71 0.62 1.65e-14 Body mass index; TGCT cis rs4321325 0.733 rs79208542 chr2:127935686 G/C cg09760422 chr2:128146352 NA 0.44 4.55 0.38 1.26e-5 Protein C levels; TGCT trans rs2727020 0.619 rs11040300 chr11:49269984 C/A cg03929089 chr4:120376271 NA 0.68 7.2 0.54 5.2e-11 Coronary artery disease; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs10875746 0.855 rs11168369 chr12:48431168 G/A cg20731937 chr12:48336164 NA 0.68 5.29 0.43 5.3e-7 Longevity (90 years and older); TGCT cis rs11148252 0.967 rs4286007 chr13:53022518 A/G cg00495681 chr13:53174319 NA 0.5 5.08 0.42 1.34e-6 Lewy body disease; TGCT cis rs2970818 0.831 rs7304949 chr12:4609625 A/G cg20471076 chr12:4920472 KCNA6 0.2 4.85 0.4 3.59e-6 Phosphorus levels; TGCT cis rs1008375 0.966 rs3733576 chr4:17586703 T/C cg10189774 chr4:17578691 LAP3 0.61 5.28 0.43 5.6e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2233152 0.520 rs56101381 chr19:41272902 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.53 4.86 0.4 3.46e-6 Kawasaki disease; TGCT cis rs4788570 0.615 rs8053745 chr16:71689693 A/G cg06353428 chr16:71660113 MARVELD3 1.56 12.36 0.74 2.34e-23 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.538 rs12603174 chr17:56489279 T/C cg25039879 chr17:56429692 SUPT4H1 0.58 4.81 0.4 4.31e-6 Cognitive test performance; TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg27535305 chr1:53392650 SCP2 -0.25 -5.06 -0.41 1.47e-6 Monocyte count; TGCT cis rs950169 0.960 rs35159785 chr15:84804014 G/A cg17173187 chr15:85201210 NMB 0.49 5.13 0.42 1.1e-6 Schizophrenia; TGCT cis rs2836974 0.666 rs4818015 chr21:40675493 A/C cg06238570 chr21:40685208 BRWD1 0.79 9.41 0.65 3.36e-16 Cognitive function; TGCT cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg22105103 chr4:187893119 NA 0.33 4.53 0.38 1.35e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 0.692 rs8043474 chr15:76974723 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs9549367 0.789 rs7317558 chr13:113893625 G/A cg00898013 chr13:113819073 PROZ -0.43 -5.5 -0.44 2.11e-7 Platelet distribution width; TGCT cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg06238570 chr21:40685208 BRWD1 -0.62 -6.17 -0.48 8.82e-9 Menarche (age at onset); TGCT cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs12220777 0.786 rs2342607 chr10:81821489 C/T cg03267442 chr10:82210566 NA 0.39 4.57 0.38 1.16e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9916302 0.718 rs10445306 chr17:37591422 A/G cg15445000 chr17:37608096 MED1 0.32 4.68 0.39 7.47e-6 Glomerular filtration rate (creatinine); TGCT cis rs11096990 0.593 rs4580660 chr4:39153836 G/A cg20847110 chr4:39482781 LOC401127 0.17 4.96 0.41 2.28e-6 Cognitive function; TGCT cis rs1008375 1.000 rs1121089 chr4:17676476 C/A cg16339924 chr4:17578868 LAP3 0.53 4.62 0.38 9.58e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg18722847 chr3:44754129 ZNF502 -0.39 -4.44 -0.37 1.94e-5 Depressive symptoms; TGCT trans rs1814175 0.817 rs28594987 chr11:50045181 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs8072100 0.782 rs62074054 chr17:45771816 T/C cg08085267 chr17:45401833 C17orf57 -0.43 -4.82 -0.4 4.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9291683 0.552 rs11736410 chr4:10017241 G/A cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Bone mineral density; TGCT cis rs11249608 0.590 rs36051170 chr5:178447971 T/C cg01312482 chr5:178451176 ZNF879 -0.58 -5.74 -0.46 7.02e-8 Pubertal anthropometrics; TGCT cis rs2732480 0.500 rs7966829 chr12:48615603 G/T cg04545296 chr12:48745243 ZNF641 0.33 4.64 0.38 8.74e-6 Hemoglobin concentration;Red blood cell count;Hematocrit; TGCT cis rs9807841 0.544 rs10417412 chr19:10766798 A/C cg17848348 chr19:10766748 ILF3 -0.4 -4.5 -0.37 1.55e-5 Inflammatory skin disease; TGCT cis rs2066819 1.000 rs118130855 chr12:56677979 T/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs7772486 0.790 rs9386141 chr6:146268623 T/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6674176 0.561 rs12127226 chr1:44395309 C/T cg12908607 chr1:44402522 ARTN -0.74 -9.15 -0.63 1.43e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7959452 0.562 rs11177630 chr12:69767963 G/C cg20891283 chr12:69753455 YEATS4 0.83 8.61 0.61 2.8e-14 Blood protein levels; TGCT cis rs2836950 0.545 rs1888489 chr21:40533164 T/C cg11644478 chr21:40555479 PSMG1 -0.52 -4.83 -0.4 3.98e-6 Menarche (age at onset); TGCT cis rs17331151 0.573 rs2240916 chr3:52859212 T/A cg15956490 chr3:53032818 SFMBT1 0.47 6.14 0.48 1.03e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6912958 0.781 rs9444524 chr6:88311260 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.48 -4.46 -0.37 1.83e-5 Monocyte percentage of white cells; TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs896854 0.517 rs10112447 chr8:95955701 C/T cg09323728 chr8:95962352 TP53INP1 -0.43 -4.92 -0.4 2.72e-6 Type 2 diabetes; TGCT cis rs524281 0.861 rs11227403 chr11:65858428 T/C cg00563793 chr11:65837595 PACS1 0.55 4.62 0.38 9.44e-6 Electroencephalogram traits; TGCT cis rs7829975 0.560 rs6994131 chr8:8550958 G/A cg15556689 chr8:8085844 FLJ10661 -0.54 -4.61 -0.38 1e-5 Mood instability; TGCT trans rs28595532 0.557 rs28657902 chr4:119305491 C/T cg26518628 chr1:97050305 NA -0.52 -7.71 -0.57 3.51e-12 Cannabis dependence symptom count; TGCT cis rs1525293 0.709 rs11984380 chr7:70481029 G/A cg21135135 chr7:70597687 WBSCR17 -0.49 -4.98 -0.41 2.08e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs826838 0.967 rs7299170 chr12:38789536 G/A cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs801193 1.000 rs2003301 chr7:66147656 G/C cg18876405 chr7:65276391 NA -0.33 -5.05 -0.41 1.55e-6 Aortic root size; TGCT cis rs6831352 0.918 rs29001232 chr4:100046654 G/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs4654899 0.931 rs6661116 chr1:21337155 C/G cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs908922 0.676 rs11205033 chr1:152527966 C/A cg20991723 chr1:152506922 NA 0.44 5.99 0.47 2.14e-8 Hair morphology; TGCT cis rs7103648 0.864 rs10742802 chr11:47432725 T/G cg20307385 chr11:47447363 PSMC3 1.02 12.61 0.75 5.75e-24 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg11494091 chr17:61959527 GH2 0.43 7.49 0.56 1.13e-11 Height; TGCT cis rs6867032 0.839 rs4314451 chr5:2001859 T/C cg26168224 chr5:2018326 NA -0.37 -5.67 -0.45 9.66e-8 Gut microbiome composition (winter); TGCT cis rs13040088 1.000 rs6090155 chr20:61527378 G/A cg23096297 chr20:61557774 DIDO1 1.13 9.5 0.65 2e-16 Menopause (age at onset); TGCT cis rs7267979 1.000 rs1888997 chr20:25298988 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs644799 1.000 rs632388 chr11:95563775 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7258465 1.000 rs7252848 chr19:18612351 C/G cg06462663 chr19:18546047 ISYNA1 0.2 4.58 0.38 1.1e-5 Breast cancer; TGCT cis rs9814567 1.000 rs4367113 chr3:134287975 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.45 -0.6 6.55e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs950776 0.616 rs12901300 chr15:78892952 G/A cg06917634 chr15:78832804 PSMA4 0.65 5.3 0.43 5.01e-7 Sudden cardiac arrest; TGCT trans rs2727020 0.658 rs10839269 chr11:49385596 A/G cg03929089 chr4:120376271 NA -0.75 -8.6 -0.61 2.96e-14 Coronary artery disease; TGCT trans rs1814175 0.817 rs10839397 chr11:49857074 C/T cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs9905704 0.671 rs28709536 chr17:57008912 C/A cg12560992 chr17:57184187 TRIM37 0.58 4.93 0.4 2.57e-6 Testicular germ cell tumor; TGCT cis rs875971 1.000 rs811880 chr7:65818646 T/C cg18876405 chr7:65276391 NA 0.32 4.93 0.4 2.61e-6 Aortic root size; TGCT cis rs782590 0.935 rs2586954 chr2:55892261 A/C cg18811423 chr2:55921094 PNPT1 0.63 6.36 0.5 3.48e-9 Metabolic syndrome; TGCT cis rs12477438 0.798 rs6705821 chr2:99602832 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs860554 0.705 rs832175 chr1:201259645 G/A cg01022117 chr1:201258280 PKP1 0.34 5.01 0.41 1.87e-6 Panic disorder; TGCT cis rs3858526 0.833 rs4758184 chr11:5926719 A/G cg13902645 chr11:5959945 NA -0.43 -4.62 -0.38 9.28e-6 DNA methylation (variation); TGCT cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs28735056 0.904 rs12962619 chr18:77628832 T/C cg20368463 chr18:77673604 PQLC1 0.4 4.89 0.4 3.09e-6 Schizophrenia; TGCT cis rs55882075 0.936 rs34646062 chr5:179186318 A/G cg14593053 chr5:179126677 CANX -0.48 -5.25 -0.43 6.37e-7 Monocyte percentage of white cells; TGCT cis rs4252435 0.614 rs4252430 chr7:142623217 T/A cg09833174 chr7:143059591 FAM131B -0.93 -4.5 -0.37 1.56e-5 Cancer; TGCT cis rs854765 0.583 rs6502619 chr17:17779704 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.98 -0.58 8.43e-13 Total body bone mineral density; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.39 5.24 0.43 6.78e-7 Lymphocyte counts; TGCT cis rs8077889 0.719 rs57227660 chr17:41858984 T/C cg26893861 chr17:41843967 DUSP3 1.11 20.15 0.88 6.31e-41 Triglycerides; TGCT cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg12310025 chr6:25882481 NA -0.53 -5.34 -0.43 4.2e-7 Height; TGCT cis rs4711350 0.678 rs658087 chr6:33665020 A/T cg00334056 chr6:33755658 LEMD2 0.34 4.53 0.38 1.35e-5 Schizophrenia; TGCT cis rs73815153 0.744 rs28415335 chr5:180459592 T/C cg00299286 chr5:180478185 BTNL9 0.87 4.98 0.41 2.08e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg08439880 chr3:133502540 NA -0.35 -6.71 -0.52 6.07e-10 Iron status biomarkers; TGCT cis rs9443645 0.869 rs2095724 chr6:79742101 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs12048904 0.505 rs10493936 chr1:101213335 A/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.56 -4.91 -0.4 2.79e-6 Multiple sclerosis; TGCT cis rs12413816 0.818 rs35567671 chr10:13769722 C/A cg16485048 chr10:13749193 FRMD4A 0.26 5.32 0.43 4.71e-7 Red cell distribution width; TGCT cis rs926938 0.618 rs360587 chr1:115467553 A/G cg12756093 chr1:115239321 AMPD1 0.4 5.93 0.47 2.85e-8 Autism; TGCT cis rs6570726 0.935 rs386344 chr6:145855622 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.66 0.39 8.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12220898 0.679 rs7082585 chr10:50486747 G/T cg09603381 chr10:49954066 WDFY4 0.39 4.62 0.38 9.57e-6 Inflammatory biomarkers; TGCT cis rs473651 0.935 rs35080527 chr2:239351387 T/C cg21699342 chr2:239360505 ASB1 0.17 4.78 0.39 4.78e-6 Multiple system atrophy; TGCT cis rs7666738 0.830 rs11940273 chr4:98979965 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10858047 0.883 rs6691804 chr1:115193549 T/C cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs10186029 0.680 rs12694293 chr2:213937221 T/C cg08319019 chr2:214017104 IKZF2 0.63 5.81 0.46 5.05e-8 Systemic sclerosis; TGCT cis rs2153535 0.580 rs1335633 chr6:8448800 C/T cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs11096990 0.634 rs12648793 chr4:39286093 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.46e-5 Cognitive function; TGCT cis rs17221829 0.733 rs10830299 chr11:89362670 C/T cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs1215050 0.791 rs649866 chr4:98738826 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.57 0.45 1.53e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs10174077 0.874 rs4664490 chr2:152471923 C/G cg06191203 chr2:152266755 RIF1 0.7 6.68 0.51 7.28e-10 Squamous cell lung carcinoma; TGCT cis rs2228479 0.717 rs2286392 chr16:89809549 A/G cg27121462 chr16:89883253 FANCA 0.77 4.61 0.38 9.93e-6 Skin colour saturation; TGCT cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg08280861 chr8:58055591 NA 0.34 4.67 0.39 7.83e-6 Developmental language disorder (linguistic errors); TGCT cis rs1185460 0.967 rs11217137 chr11:118931030 A/G cg01677386 chr11:118938358 VPS11 -0.56 -4.71 -0.39 6.62e-6 Coronary artery disease; TGCT trans rs71007656 1 rs71007656 chr10:37970845 CGGCTG/C cg17830980 chr10:43048298 ZNF37B -0.66 -7.47 -0.56 1.22e-11 Extrinsic epigenetic age acceleration; TGCT cis rs3540 0.554 rs34650360 chr15:91059017 T/C cg22089800 chr15:90895588 ZNF774 -0.76 -7.96 -0.58 9.33e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg11494091 chr17:61959527 GH2 0.43 7.3 0.55 3.05e-11 Height; TGCT cis rs7017914 0.902 rs7831792 chr8:71565356 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.5 -4.68 -0.39 7.37e-6 Bone mineral density; TGCT cis rs6854137 1.000 rs6854137 chr4:169728236 T/G cg20607169 chr4:169750834 PALLD 0.23 4.97 0.41 2.13e-6 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs2197308 0.655 rs1971964 chr12:37870474 C/T cg13010199 chr12:38710504 ALG10B 0.67 5.31 0.43 4.84e-7 Morning vs. evening chronotype; TGCT cis rs6714710 0.603 rs116309486 chr2:98493359 A/G cg26665480 chr2:98280029 ACTR1B 0.64 6.06 0.48 1.48e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs17376456 0.569 rs7736892 chr5:93205597 G/A cg25358565 chr5:93447407 FAM172A -0.8 -6.09 -0.48 1.31e-8 Diabetic retinopathy; TGCT cis rs9388451 0.839 rs9321054 chr6:126079968 A/G cg10911889 chr6:126070802 HEY2 -0.53 -5.52 -0.44 1.88e-7 Brugada syndrome; TGCT cis rs16975963 0.793 rs1807157 chr19:38465523 G/T cg14550563 chr19:38990264 RYR1 0.28 4.58 0.38 1.09e-5 Longevity; TGCT cis rs1784581 0.588 rs9295178 chr6:162419226 T/A cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg23719950 chr11:63933701 MACROD1 -0.72 -5.92 -0.47 2.99e-8 Mean platelet volume; TGCT cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg24675658 chr1:53192096 ZYG11B 0.74 8.68 0.61 1.87e-14 Monocyte count; TGCT cis rs3806843 0.576 rs246062 chr5:140324580 T/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs428668 0.523 rs3926389 chr5:150677806 C/T cg11125805 chr5:150678162 SLC36A3 0.31 7.89 0.58 1.37e-12 Skin aging (microtopography measurement); TGCT cis rs6540559 0.673 rs1073150 chr1:210017083 G/A cg21951975 chr1:209979733 IRF6 0.63 4.76 0.39 5.36e-6 Cleft lip with or without cleft palate; TGCT cis rs36051895 0.626 rs9695934 chr9:5153108 C/G cg02405213 chr9:5042618 JAK2 -0.73 -9.46 -0.65 2.54e-16 Pediatric autoimmune diseases; TGCT cis rs7582180 0.591 rs11674569 chr2:101010860 G/A cg08017756 chr2:100939284 LONRF2 -0.31 -4.87 -0.4 3.32e-6 Intelligence (multi-trait analysis); TGCT cis rs9486719 1.000 rs2205755 chr6:96864704 A/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs5417 0.751 rs1634381 chr17:7180007 C/T cg25256661 chr17:7137939 DVL2 -0.62 -6.13 -0.48 1.07e-8 Diastolic blood pressure; TGCT cis rs9911578 0.967 rs7502208 chr17:57165097 G/A cg12560992 chr17:57184187 TRIM37 0.78 9.66 0.66 8.55e-17 Intelligence (multi-trait analysis); TGCT cis rs6424115 0.867 rs10917431 chr1:24174093 T/G cg15997130 chr1:24165203 NA -0.89 -10.18 -0.67 4.6e-18 Immature fraction of reticulocytes; TGCT cis rs10466239 0.730 rs12221341 chr10:43857330 C/G cg20669305 chr10:44070200 ZNF239 -0.66 -4.45 -0.37 1.86e-5 Telomere length; TGCT trans rs6089829 0.962 rs9679865 chr20:61666132 C/G cg17470723 chr8:74884337 TCEB1 0.74 6.92 0.53 2.19e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.861 rs2448792 chr1:53268313 T/C cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs9303401 0.659 rs35564417 chr17:56718286 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs12421382 0.778 rs12804063 chr11:109495509 C/T cg16359550 chr11:109292809 C11orf87 -0.49 -4.88 -0.4 3.23e-6 Schizophrenia; TGCT cis rs7394190 0.748 rs11000728 chr10:75404300 C/G cg07699608 chr10:75541558 CHCHD1 0.62 4.64 0.38 8.58e-6 Incident atrial fibrillation; TGCT cis rs7769051 1.000 rs9493445 chr6:133125409 C/T cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs8072100 0.544 rs7214993 chr17:45386797 C/G cg08085267 chr17:45401833 C17orf57 -0.49 -5.58 -0.45 1.47e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.84 0.4 3.86e-6 Platelet count; TGCT cis rs7523050 0.643 rs35526993 chr1:109405107 A/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs6933660 0.665 rs6921042 chr6:151732385 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.65 6.34 0.49 3.82e-9 Menarche (age at onset); TGCT cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs4523957 0.614 rs7212964 chr17:2059319 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9926296 0.527 rs1800335 chr16:89846195 A/G cg26513180 chr16:89883248 FANCA 1.05 14.37 0.79 3.52e-28 Vitiligo; TGCT cis rs3935685 0.874 rs4076998 chr15:78025420 T/G cg25212270 chr15:78015279 NA 0.27 5.84 0.46 4.38e-8 Intelligence (multi-trait analysis); TGCT cis rs911186 0.786 rs72842197 chr6:27067083 C/T cg16898833 chr6:26189333 HIST1H4D 0.8 4.85 0.4 3.57e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9457247 0.534 rs4710149 chr6:167386346 T/C cg23791538 chr6:167370224 RNASET2 0.63 6.27 0.49 5.55e-9 Crohn's disease; TGCT cis rs6690583 0.623 rs1371142 chr1:85455373 A/T cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs9467773 1.000 rs9461259 chr6:26504835 C/A cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg21951975 chr1:209979733 IRF6 0.7 6.01 0.47 1.92e-8 Cleft lip with or without cleft palate; TGCT cis rs7568458 0.684 rs1048739 chr2:85764968 T/G cg02493740 chr2:85810744 VAMP5 -0.28 -5.26 -0.43 6.1e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1018836 0.632 rs9642910 chr8:91475724 G/T cg16814680 chr8:91681699 NA -0.8 -8.32 -0.6 1.33e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs611744 0.967 rs641721 chr8:109230140 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs3812831 0.695 rs423237 chr13:114930955 C/T cg06611532 chr13:114900021 NA 0.35 6.42 0.5 2.57e-9 Schizophrenia; TGCT trans rs61931739 0.500 rs11053203 chr12:34456593 C/T cg26384229 chr12:38710491 ALG10B 0.73 6.92 0.53 2.09e-10 Morning vs. evening chronotype; TGCT cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.51 4.49 0.37 1.58e-5 Height; TGCT cis rs877282 0.947 rs4133015 chr10:774131 T/C cg17470449 chr10:769945 NA 0.3 4.77 0.39 5.05e-6 Uric acid levels; TGCT cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg11644478 chr21:40555479 PSMG1 1.01 10.73 0.69 2.08e-19 Cognitive function; TGCT cis rs12500482 0.935 rs2239736 chr4:2438929 T/C cg01601518 chr4:2404284 ZFYVE28 -0.28 -4.62 -0.38 9.36e-6 Cognitive function; TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg16325326 chr1:53192061 ZYG11B 0.5 5.59 0.45 1.38e-7 Monocyte count; TGCT cis rs9326248 0.520 rs2735183 chr11:117015195 C/T cg01368799 chr11:117014884 PAFAH1B2 0.59 5.32 0.43 4.69e-7 Blood protein levels; TGCT cis rs707040 1.000 rs1154759 chr2:155236334 G/A cg18104148 chr2:154337490 NA 0.19 4.56 0.38 1.2e-5 Sudden cardiac arrest; TGCT cis rs1865760 0.516 rs9379819 chr6:26049819 A/C cg17042849 chr6:26104293 HIST1H4C -0.65 -5.76 -0.46 6.19e-8 Height; TGCT cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg05025164 chr4:1340916 KIAA1530 0.76 6.51 0.5 1.65e-9 Longevity; TGCT cis rs826838 0.967 rs11168299 chr12:38902028 G/T cg13010199 chr12:38710504 ALG10B 0.78 6.42 0.5 2.61e-9 Heart rate; TGCT cis rs4819052 0.851 rs1056100 chr21:46678711 A/C cg06618935 chr21:46677482 NA -0.36 -5.37 -0.43 3.67e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg07424592 chr7:64974309 NA 1.26 8.11 0.59 4.17e-13 Diabetic kidney disease; TGCT trans rs7618501 1.000 rs9855505 chr3:49792158 T/G cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs425277 1.000 rs262657 chr1:2088577 G/A cg03732007 chr1:2071316 PRKCZ 0.26 5.33 0.43 4.49e-7 Height; TGCT cis rs910316 1.000 rs7142235 chr14:75559963 T/C cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT cis rs5167 0.601 rs892131 chr19:45496996 C/T cg13119609 chr19:45449297 APOC2 0.23 4.65 0.39 8.26e-6 Blood protein levels; TGCT cis rs2832191 0.935 rs11910316 chr21:30519729 G/A cg24692254 chr21:30365293 RNF160 -0.79 -8.35 -0.6 1.12e-13 Dental caries; TGCT cis rs9611565 0.512 rs5758465 chr22:42175314 T/C cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs10949834 0.824 rs2285025 chr7:73529976 T/C cg07137043 chr7:73588983 EIF4H -0.74 -4.53 -0.38 1.38e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs11098499 0.909 rs10020034 chr4:120294331 A/G cg09307838 chr4:120376055 NA 0.65 6.4 0.5 2.84e-9 Corneal astigmatism; TGCT cis rs12950390 0.820 rs58391889 chr17:45865959 A/G cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.63e-6 IgG glycosylation; TGCT cis rs262150 0.579 rs4481540 chr7:158785846 A/G cg01219135 chr7:158766336 NA -0.47 -4.86 -0.4 3.46e-6 Facial morphology (factor 20); TGCT cis rs61884328 0.852 rs17790390 chr11:47151897 A/G cg13308137 chr11:47528955 CUGBP1 -0.38 -4.59 -0.38 1.09e-5 Total body bone mineral density (age over 60); TGCT cis rs1729951 0.575 rs168635 chr3:136699078 A/G cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs367615 0.918 rs4270746 chr5:108876839 T/C cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs10992471 0.597 rs11789163 chr9:95234973 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.39 -0.44 3.43e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7572733 0.515 rs13408411 chr2:198825462 G/A cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs9467773 1.000 rs10946835 chr6:26533757 C/T cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs6558530 0.692 rs6558522 chr8:1702370 C/G cg09410841 chr8:1729607 CLN8 -0.69 -6.1 -0.48 1.22e-8 Systolic blood pressure; TGCT cis rs453301 0.686 rs7017868 chr8:8873293 G/A cg15556689 chr8:8085844 FLJ10661 -0.64 -5.29 -0.43 5.37e-7 Joint mobility (Beighton score); TGCT cis rs36051895 0.695 rs60221565 chr9:5029077 T/G cg02405213 chr9:5042618 JAK2 -0.77 -10.43 -0.68 1.16e-18 Pediatric autoimmune diseases; TGCT cis rs2675662 0.525 rs12264025 chr10:75494450 A/G cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Psoriasis vulgaris;Psoriasis; TGCT cis rs11249608 0.600 rs6859767 chr5:178451107 T/C cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs7772486 0.875 rs9322046 chr6:146393625 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.59 0.65 1.22e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs916888 0.610 rs199436 chr17:44789285 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.59 -4.73 -0.39 6.05e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2836974 0.831 rs2836921 chr21:40516070 C/T cg17971929 chr21:40555470 PSMG1 0.95 9.06 0.63 2.31e-15 Cognitive function; TGCT cis rs6964587 0.900 rs6972027 chr7:91781380 T/C cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.33e-6 Breast cancer; TGCT cis rs2153535 0.526 rs9406179 chr6:8538224 G/A cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs514406 0.621 rs928452 chr1:53195926 G/C cg25767906 chr1:53392781 SCP2 0.44 4.79 0.4 4.68e-6 Monocyte count; TGCT cis rs9465539 0.544 rs6910773 chr6:19820658 T/C cg23687194 chr6:19839375 ID4 0.56 4.53 0.38 1.35e-5 Neuroticism; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs17376456 0.877 rs7702521 chr5:93484579 G/T cg21475434 chr5:93447410 FAM172A 0.63 4.67 0.39 7.67e-6 Diabetic retinopathy; TGCT cis rs2562456 0.876 rs7252585 chr19:21657943 C/T cg25650185 chr19:21324782 ZNF431 0.56 4.79 0.4 4.63e-6 Pain; TGCT cis rs514406 0.505 rs447581 chr1:53177098 T/C cg25767906 chr1:53392781 SCP2 -0.47 -5.22 -0.42 7.39e-7 Monocyte count; TGCT cis rs35883536 1.000 rs2297715 chr1:101092594 A/G cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.19e-5 Monocyte count; TGCT cis rs3008870 0.920 rs12132532 chr1:67457015 G/T cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs1865760 0.516 rs9379819 chr6:26049819 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.39 0.55 1.92e-11 Height; TGCT cis rs903263 0.901 rs3768258 chr1:84670457 A/G cg09664975 chr1:84543551 PRKACB 0.49 4.69 0.39 7.19e-6 Breast cancer (male); TGCT cis rs904251 0.600 rs1874736 chr6:37447994 C/G cg01843034 chr6:37503916 NA -0.47 -6.02 -0.48 1.83e-8 Cognitive performance; TGCT cis rs10904908 0.763 rs10795469 chr10:17334935 A/G cg01003015 chr10:17271136 VIM 0.58 4.68 0.39 7.45e-6 Total cholesterol levels;Cholesterol, total; TGCT cis rs5750830 0.645 rs756640 chr22:39779300 G/A cg05872129 chr22:39784769 NA -0.96 -11.07 -0.7 3.18e-20 Intelligence (multi-trait analysis); TGCT cis rs11690935 0.879 rs908671 chr2:172690265 C/G cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.01 -0.73 1.6400000000000001e-22 Schizophrenia; TGCT cis rs9987353 0.522 rs2929466 chr8:9063899 G/T cg06636001 chr8:8085503 FLJ10661 -0.52 -5.01 -0.41 1.8e-6 Recombination measurement; TGCT cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs6088580 0.609 rs6058029 chr20:32969643 T/C cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs3829109 0.564 rs11145910 chr9:139300494 A/G cg13741927 chr9:139327495 INPP5E -0.24 -5.32 -0.43 4.78e-7 Peak insulin response;Acute insulin response; TGCT trans rs17684571 0.938 rs17684511 chr6:56566015 G/C cg14229071 chr15:89282588 NA 0.52 6.82 0.52 3.54e-10 Schizophrenia; TGCT cis rs7014346 0.767 rs2060776 chr8:128420117 G/T cg04263511 chr8:128962092 PVT1 -0.31 -4.55 -0.38 1.25e-5 Colorectal cancer; TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.13 0.82 3.12e-32 Prudent dietary pattern; TGCT cis rs10479542 0.721 rs6894113 chr5:178974789 G/C cg22764044 chr5:178986830 RUFY1 0.42 4.73 0.39 5.98e-6 Lung cancer; TGCT cis rs11098499 0.954 rs10518328 chr4:120401779 G/A cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs35771425 0.500 rs3738199 chr1:211545344 A/G cg25617285 chr1:211431773 RCOR3 -0.51 -6.16 -0.48 9.51e-9 Educational attainment (years of education); TGCT cis rs2046867 0.908 rs28822756 chr3:72825011 C/T cg25664220 chr3:72788482 NA -0.53 -6.73 -0.52 5.56e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7223966 1.000 rs7220892 chr17:61908316 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs514406 0.825 rs497535 chr1:53284677 A/G cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs12908161 0.959 rs11637728 chr15:85203392 A/T cg17173187 chr15:85201210 NMB 0.57 6.33 0.49 4.18e-9 Schizophrenia; TGCT cis rs17253792 0.822 rs2296181 chr14:56107051 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs7091068 0.532 rs637959 chr10:95399031 T/C cg20715218 chr10:95462985 C10orf4 -0.49 -5.9 -0.47 3.27e-8 Urinary tract infection frequency; TGCT cis rs67311347 0.911 rs9849224 chr3:40392562 T/C cg13683864 chr3:40499215 RPL14 -1.02 -10.8 -0.7 1.43e-19 Renal cell carcinoma; TGCT cis rs67311347 1.000 rs28434528 chr3:40484893 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs2688608 1.000 rs2688608 chr10:75658349 G/T cg19442545 chr10:75533431 FUT11 -0.3 -4.75 -0.39 5.44e-6 Inflammatory bowel disease; TGCT cis rs295140 0.565 rs295139 chr2:201159988 T/A cg23649088 chr2:200775458 C2orf69 0.27 4.5 0.37 1.54e-5 QT interval; TGCT cis rs2235649 0.588 rs11863172 chr16:1909083 C/G cg02432467 chr16:1963432 HS3ST6 -0.32 -4.6 -0.38 1.02e-5 Blood metabolite levels; TGCT cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs11676348 0.846 rs6723449 chr2:218997580 C/T cg00012203 chr2:219082015 ARPC2 0.51 4.85 0.4 3.59e-6 Ulcerative colitis; TGCT cis rs3008870 1.000 rs1118393 chr1:67366668 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.84 0.73 4.25e-22 Lymphocyte percentage of white cells; TGCT cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg08219700 chr8:58056026 NA 0.3 4.55 0.38 1.25e-5 Developmental language disorder (linguistic errors); TGCT cis rs155076 1.000 rs58519241 chr13:21845006 C/A cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs9926296 0.744 rs164746 chr16:89709019 C/T cg26513180 chr16:89883248 FANCA -0.57 -5.42 -0.44 3.04e-7 Vitiligo; TGCT cis rs7647973 0.925 rs6446257 chr3:49253492 A/G cg07636037 chr3:49044803 WDR6 -0.69 -5.82 -0.46 4.72e-8 Menarche (age at onset); TGCT cis rs12579753 0.709 rs34503239 chr12:82124199 G/T cg21231944 chr12:82153410 PPFIA2 -0.36 -4.75 -0.39 5.5e-6 Resting heart rate; TGCT cis rs2228479 0.681 rs8044906 chr16:89969603 T/C cg27121462 chr16:89883253 FANCA 0.62 4.51 0.38 1.51e-5 Skin colour saturation; TGCT cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg01802117 chr1:53393560 SCP2 0.47 5.77 0.46 5.88e-8 Monocyte count; TGCT cis rs7617773 0.817 rs9837228 chr3:48324466 A/T cg11946769 chr3:48343235 NME6 -0.72 -6.16 -0.48 9.39e-9 Coronary artery disease; TGCT cis rs12479064 0.604 rs11893359 chr2:99954608 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.77 -6.7 -0.52 6.68e-10 Chronic sinus infection; TGCT trans rs57221529 0.766 rs56350081 chr5:583198 G/A cg11887960 chr12:57824829 NA 1.14 9.3 0.64 6.29e-16 Lung disease severity in cystic fibrosis; TGCT cis rs3751972 0.911 rs8078361 chr17:26230480 C/T cg02948944 chr17:26242737 NA 0.5 7.28 0.55 3.35e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs56104184 0.779 rs17206693 chr19:49360252 C/G cg21252483 chr19:49399788 TULP2 -0.4 -5.09 -0.42 1.27e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs67311347 0.544 rs6804545 chr3:40354040 G/C cg13683864 chr3:40499215 RPL14 -0.8 -7.5 -0.56 1.09e-11 Renal cell carcinoma; TGCT cis rs7312933 0.558 rs2178753 chr12:42732804 T/C cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.18e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg08280861 chr8:58055591 NA 0.46 5.19 0.42 8.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs13191362 1.000 rs13218900 chr6:163081638 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.36 0.6 1.07e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs8180040 0.726 rs1869869 chr3:47027833 G/A cg27129171 chr3:47204927 SETD2 0.72 9.15 0.63 1.47e-15 Colorectal cancer; TGCT cis rs2439831 0.867 rs2412780 chr15:43655794 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs3862030 0.500 rs11191327 chr10:104303883 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.72 0.62 1.54e-14 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs1524927 1.000 rs11765843 chr7:96341168 T/A cg03808172 chr7:96339361 SHFM1 0.49 5.06 0.41 1.45e-6 Total body bone mineral density; TGCT cis rs56235845 0.964 rs11741640 chr5:176792743 G/A cg16006841 chr5:176797999 RGS14 0.72 12.49 0.75 1.09e-23 Hemoglobin concentration;Hematocrit; TGCT cis rs17384381 1.000 rs12133722 chr1:85873237 C/T cg16011679 chr1:85725395 C1orf52 0.8 6.44 0.5 2.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2439831 0.717 rs7165471 chr15:43644788 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs7302981 0.967 rs6580729 chr12:50547038 G/A cg23855989 chr12:50355821 AQP5 0.3 4.5 0.38 1.52e-5 Systolic blood pressure; TGCT cis rs67385638 0.925 rs12417960 chr11:5265106 C/A cg12559170 chr11:5275217 HBG2 0.49 8.65 0.61 2.2e-14 Hemoglobin levels; TGCT cis rs798554 0.679 rs11973498 chr7:2886873 C/A cg13628971 chr7:2884303 GNA12 0.54 4.64 0.38 8.74e-6 Height; TGCT trans rs2688482 0.512 rs1106502 chr3:195517258 G/A cg17952111 chr19:54960355 LENG8 0.83 6.82 0.52 3.57e-10 Lung disease severity in cystic fibrosis; TGCT cis rs769267 0.930 rs747050 chr19:19584987 C/G cg03709012 chr19:19516395 GATAD2A 0.75 6.18 0.49 8.32e-9 Tonsillectomy; TGCT cis rs9611565 0.918 rs2281333 chr22:41749630 T/C cg06634786 chr22:41940651 POLR3H -0.79 -7.66 -0.57 4.71e-12 Vitiligo; TGCT cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg10117171 chr1:25599238 RHD -0.36 -5.73 -0.46 7.35e-8 Erythrocyte sedimentation rate; TGCT cis rs1371867 0.839 rs1660313 chr8:101332712 G/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs1981331 0.609 rs57896262 chr21:48028188 C/T cg23283320 chr21:48055893 PRMT2 1.33 7.14 0.54 7.05e-11 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg17775962 chr7:1200435 ZFAND2A 0.3 4.98 0.41 2.05e-6 Longevity;Endometriosis; TGCT trans rs7618501 0.602 rs2240327 chr3:50113034 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.5 0.65 2.02e-16 Intelligence (multi-trait analysis); TGCT cis rs4699052 0.963 rs4699057 chr4:104171123 A/G cg16532752 chr4:104119610 CENPE 0.54 4.56 0.38 1.22e-5 Testicular germ cell tumor; TGCT cis rs2576037 0.583 rs2156049 chr18:44455717 G/A cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg20007245 chr22:24372913 LOC391322 -0.65 -6.44 -0.5 2.34e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs524023 0.957 rs528211 chr11:64351721 C/T cg07733098 chr11:64478343 NRXN2 -0.31 -4.63 -0.38 9.14e-6 Urate levels in obese individuals; TGCT cis rs7110373 1 rs7110373 chr11:122813224 C/T cg14473756 chr11:122847823 NA -0.47 -4.63 -0.38 8.99e-6 Age at voice drop; TGCT cis rs2982552 0.873 rs3020305 chr6:152064487 T/C cg22157087 chr6:152012887 ESR1 0.21 4.93 0.4 2.61e-6 Bone properties (heel); TGCT cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg17054783 chr10:134559939 INPP5A 0.27 5.15 0.42 1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3849570 1.000 rs9826270 chr3:81841869 C/T cg07356753 chr3:81810745 GBE1 -0.82 -7.62 -0.56 5.6e-12 Waist circumference;Body mass index; TGCT cis rs9926296 0.569 rs4785708 chr16:89796569 C/T cg26513180 chr16:89883248 FANCA -0.65 -6.28 -0.49 5.24e-9 Vitiligo; TGCT cis rs7119 0.717 rs12910975 chr15:77817487 C/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs11711311 1.000 rs13061150 chr3:113506734 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.64 -0.51 8.96e-10 IgG glycosylation; TGCT cis rs28595532 0.920 rs56027489 chr4:119780882 A/G cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT trans rs7824557 0.510 rs2736297 chr8:11234885 C/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.42e-10 Retinal vascular caliber; TGCT cis rs7726839 0.561 rs3915384 chr5:573395 G/T cg09021430 chr5:549028 NA -0.38 -5.56 -0.45 1.6e-7 Obesity-related traits; TGCT cis rs66782572 1 rs66782572 chr3:52567617 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.56 -5.49 -0.44 2.13e-7 Hemoglobin concentration; TGCT cis rs9457247 0.565 rs55873403 chr6:167511800 C/T cg07741184 chr6:167504864 NA 0.28 5.6 0.45 1.33e-7 Crohn's disease; TGCT cis rs4886920 0.563 rs4509984 chr15:78079267 C/G cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.37e-6 Neuroticism; TGCT cis rs7432375 0.578 rs17366234 chr3:136577085 C/T cg12473912 chr3:136751656 NA 0.34 4.67 0.39 7.67e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs13191362 0.507 rs2849540 chr6:163094522 G/A cg06582575 chr6:163149167 PACRG;PARK2 -0.6 -5.55 -0.45 1.67e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3806843 0.868 rs2531345 chr5:140126781 T/G cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 1.000 rs111915672 chr8:58191665 T/C cg21724239 chr8:58056113 NA 0.38 5.09 0.42 1.31e-6 Developmental language disorder (linguistic errors); TGCT cis rs3733585 0.648 rs7376155 chr4:9952588 C/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.63 -0.51 9.3e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12220898 0.584 rs10857455 chr10:50474712 A/T cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.85e-5 Inflammatory biomarkers; TGCT cis rs11018874 0.709 rs10830428 chr11:89894294 C/G cg05041596 chr11:89867385 NAALAD2 -0.52 -5.2 -0.42 8.14e-7 White blood cell types; TGCT cis rs8032315 0.965 rs8027450 chr15:91418394 C/T cg03209642 chr15:91427605 FES 0.55 5.41 0.44 3.11e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9486719 0.895 rs3734238 chr6:96996228 A/T cg06623918 chr6:96969491 KIAA0776 -0.99 -7.99 -0.58 7.78e-13 Migraine;Coronary artery disease; TGCT trans rs1814175 0.791 rs10219223 chr11:49791468 A/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.46 -0.56 1.33e-11 Height; TGCT cis rs9902453 0.817 rs59420007 chr17:28196114 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.62e-11 Coffee consumption (cups per day); TGCT trans rs12599106 0.792 rs12597352 chr16:34638507 A/T cg26668828 chr6:292823 DUSP22 -0.76 -7.85 -0.58 1.66e-12 Menopause (age at onset); TGCT cis rs9486719 0.947 rs11153071 chr6:97039741 G/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs10504229 0.683 rs61306359 chr8:58134646 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7508 0.612 rs17636098 chr8:17918726 G/A cg01800426 chr8:17659068 MTUS1 0.52 4.51 0.38 1.49e-5 Atrial fibrillation; TGCT cis rs1538970 0.924 rs7531253 chr1:45890183 T/C cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs9814567 0.762 rs13071253 chr3:134316653 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.82 6.63 0.51 9.15e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs28374715 0.662 rs72737786 chr15:41500361 G/T cg18705301 chr15:41695430 NDUFAF1 -0.78 -11.07 -0.7 3.18e-20 Ulcerative colitis; TGCT cis rs7772486 0.686 rs857882 chr6:145969716 T/G cg13319975 chr6:146136371 FBXO30 0.54 4.98 0.41 2.09e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg06221963 chr1:154839813 KCNN3 -0.71 -11.67 -0.72 1.1e-21 Prostate cancer; TGCT cis rs736408 0.812 rs2071507 chr3:52826707 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.53 -0.38 1.39e-5 Bipolar disorder; TGCT cis rs826838 1.000 rs11168367 chr12:38913397 T/G cg13010199 chr12:38710504 ALG10B 0.77 6.38 0.5 3.21e-9 Heart rate; TGCT cis rs7681440 0.605 rs1372509 chr4:90817311 A/G cg20003494 chr4:90757398 SNCA -0.54 -4.88 -0.4 3.21e-6 Dementia with Lewy bodies; TGCT cis rs854765 0.533 rs2955354 chr17:17948716 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs6545883 0.965 rs2305156 chr2:61729268 T/C cg15711740 chr2:61764176 XPO1 -0.54 -4.95 -0.41 2.39e-6 Tuberculosis; TGCT cis rs12477438 0.798 rs7570657 chr2:99654281 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs9926296 0.632 rs9935559 chr16:89800529 C/T cg03388025 chr16:89894329 SPIRE2 -0.33 -4.9 -0.4 2.89e-6 Vitiligo; TGCT cis rs634534 0.622 rs552130 chr11:65732800 T/C cg04055107 chr11:65626734 MUS81;CFL1 0.45 4.47 0.37 1.73e-5 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg06697600 chr4:7070879 GRPEL1 -0.45 -4.69 -0.39 7e-6 Monocyte percentage of white cells; TGCT cis rs7267979 1.000 rs2258066 chr20:25271326 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs769267 0.965 rs2315025 chr19:19426609 C/T cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs911263 0.603 rs12889949 chr14:68774854 T/G cg18825221 chr14:68749962 RAD51L1 0.22 4.48 0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs1218582 0.740 rs1977879 chr1:154879743 G/A cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs5167 0.566 rs35080293 chr19:45496624 T/G cg13119609 chr19:45449297 APOC2 0.24 4.7 0.39 6.88e-6 Blood protein levels; TGCT cis rs651907 0.557 rs62284198 chr3:101474699 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.9 10.87 0.7 9.43e-20 Colorectal cancer; TGCT cis rs2836950 0.565 rs2836945 chr21:40596757 C/T cg06238570 chr21:40685208 BRWD1 -0.6 -6.21 -0.49 7.27e-9 Menarche (age at onset); TGCT cis rs76419734 0.850 rs115962916 chr4:106801715 C/T cg24545054 chr4:106630052 GSTCD;INTS12 1.01 4.61 0.38 9.71e-6 Post bronchodilator FEV1; TGCT cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg15691649 chr6:25882328 NA -0.35 -4.75 -0.39 5.41e-6 Blood metabolite levels; TGCT cis rs9427116 0.502 rs9426830 chr1:154594690 A/G cg17218026 chr1:154582156 ADAR 0.31 7.97 0.58 8.71e-13 Blood protein levels; TGCT cis rs7975161 0.630 rs4964260 chr12:104634270 A/G cg25273343 chr12:104657179 TXNRD1 -0.35 -4.83 -0.4 3.87e-6 Toenail selenium levels; TGCT cis rs910316 0.967 rs175479 chr14:75561871 A/C cg11812906 chr14:75593930 NEK9 -0.76 -7.41 -0.55 1.69e-11 Height; TGCT cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg14983838 chr19:29218262 NA 0.83 6.81 0.52 3.8e-10 Methadone dose in opioid dependence; TGCT cis rs4665809 1.000 rs2053367 chr2:26293413 T/C cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs12188164 0.762 rs11745923 chr5:475408 T/G cg21144161 chr5:423903 AHRR 0.26 4.81 0.4 4.22e-6 Cystic fibrosis severity; TGCT cis rs3931020 0.530 rs6668736 chr1:75234550 C/T cg17719053 chr1:75198211 TYW3;CRYZ 0.49 5.05 0.41 1.53e-6 Resistin levels; TGCT cis rs2832191 0.692 rs8134627 chr21:30349069 C/T cg24692254 chr21:30365293 RNF160 -0.99 -11.38 -0.71 5.44e-21 Dental caries; TGCT cis rs9400467 0.537 rs73530977 chr6:111504819 C/T cg15721981 chr6:111408429 SLC16A10 0.71 4.6 0.38 1.04e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs1215050 0.791 rs260889 chr4:98742340 A/G cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7914558 0.902 rs7092200 chr10:104844872 T/C cg04362960 chr10:104952993 NT5C2 0.54 4.65 0.39 8.38e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2458413 0.522 rs2669449 chr8:105372173 A/C cg04554929 chr8:105342491 NA 0.48 5.77 0.46 5.95e-8 Paget's disease; TGCT cis rs2236918 1.000 rs1627006 chr1:242038004 C/T cg04158730 chr1:242011433 EXO1 0.53 4.64 0.38 8.79e-6 Menopause (age at onset); TGCT cis rs6540559 0.673 rs41305104 chr1:209950848 G/A cg22029157 chr1:209979665 IRF6 0.73 5.21 0.42 7.62e-7 Cleft lip with or without cleft palate; TGCT cis rs10782582 0.609 rs76260657 chr1:76338017 C/T cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs3125734 0.671 rs3852406 chr10:64015162 T/C cg09941381 chr10:64027924 RTKN2 -0.36 -5.52 -0.44 1.85e-7 Rheumatoid arthritis; TGCT cis rs769267 0.965 rs2315024 chr19:19423817 T/A cg03709012 chr19:19516395 GATAD2A 0.67 5.77 0.46 5.88e-8 Tonsillectomy; TGCT cis rs7681440 0.626 rs2289515 chr4:90816790 T/A cg10208370 chr4:90758469 SNCA -0.57 -5.41 -0.44 3.05e-7 Dementia with Lewy bodies; TGCT cis rs2742417 1.000 rs2742418 chr3:45731920 C/T cg04837898 chr3:45731254 SACM1L -0.55 -5.67 -0.45 9.39e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs13188386 0.585 rs7716495 chr5:42428091 G/A cg14919554 chr5:43018629 NA 0.59 4.55 0.38 1.25e-5 Iron status biomarkers; TGCT cis rs10114408 0.959 rs11791409 chr9:96642124 T/C cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 4.69 0.39 7.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs72634258 0.554 rs35307738 chr1:7919839 C/G cg26816564 chr1:7831052 VAMP3 0.64 4.94 0.41 2.46e-6 Inflammatory bowel disease; TGCT cis rs2072499 0.966 rs2842865 chr1:156159532 G/A cg24450063 chr1:156163899 SLC25A44 1.19 17.21 0.84 1.15e-34 Testicular germ cell tumor; TGCT cis rs7714584 1.000 rs79780973 chr5:150174810 T/C cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs2180341 1.000 rs9388561 chr6:127634921 C/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs597539 0.731 rs664229 chr11:68624483 C/G cg21963583 chr11:68658836 MRPL21 0.39 6.34 0.49 3.91e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4665809 0.652 rs6728090 chr2:26524726 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.94 -6.76 -0.52 4.89e-10 Gut microbiome composition (summer); TGCT cis rs1568889 1.000 rs12804198 chr11:28143114 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 9.0 0.63 3.18e-15 Bipolar disorder; TGCT cis rs11190604 1.000 rs11190557 chr10:102209369 G/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6835098 0.962 rs3733477 chr4:174090004 G/A cg08422745 chr4:174089978 GALNT7 -0.95 -11.46 -0.72 3.51e-21 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9473924 0.505 rs7768747 chr6:50931762 G/A cg14470998 chr6:50812995 TFAP2B 1.37 7.34 0.55 2.4e-11 Body mass index; TGCT cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs6545883 0.965 rs11887205 chr2:61774473 T/G cg15711740 chr2:61764176 XPO1 -0.55 -5.06 -0.41 1.5e-6 Tuberculosis; TGCT cis rs7927484 0.891 rs2000796 chr11:123136552 A/G cg19096475 chr11:123066529 ASAM -0.48 -4.79 -0.4 4.59e-6 Colorectal cancer;Colonoscopy-negative controls vs population controls; TGCT cis rs4319547 1.000 rs6489157 chr12:123101673 C/G cg05707623 chr12:122985044 ZCCHC8 0.69 5.44 0.44 2.68e-7 Body mass index; TGCT cis rs4808199 0.895 rs2285628 chr19:19467996 T/A cg03709012 chr19:19516395 GATAD2A 0.84 6.72 0.52 5.97e-10 Nonalcoholic fatty liver disease; TGCT cis rs6570726 0.755 rs2092296 chr6:145893684 A/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6570726 0.818 rs437147 chr6:145875423 A/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs916888 0.610 rs142167 chr17:44795234 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.59 -4.64 -0.38 8.84e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28493229 0.522 rs2233152 chr19:41281016 C/T cg00475131 chr19:41117096 LTBP4 0.29 4.49 0.37 1.61e-5 Kawasaki disease; TGCT cis rs35146811 0.700 rs866500 chr7:99840461 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.34 -4.61 -0.38 9.7e-6 Coronary artery disease; TGCT cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg08859206 chr1:53392774 SCP2 0.41 6.06 0.48 1.54e-8 Monocyte count; TGCT cis rs75229567 0.618 rs11177848 chr12:70180892 A/G cg10114359 chr12:70132523 RAB3IP 1.35 6.71 0.52 6.17e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs9303401 0.659 rs17822735 chr17:56620167 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs892961 0.899 rs8071024 chr17:75414067 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.71 0.52 6.16e-10 Airflow obstruction; TGCT cis rs9467773 0.967 rs6932865 chr6:26540166 C/A cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs9972944 0.756 rs4791133 chr17:63769118 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs9457247 0.967 rs2015864 chr6:167381476 T/C cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.08e-6 Crohn's disease; TGCT trans rs1814175 0.647 rs28456013 chr11:50047629 T/C cg03929089 chr4:120376271 NA -0.59 -6.66 -0.51 7.82e-10 Height; TGCT cis rs6893807 0.778 rs10514301 chr5:87939654 C/T cg24804195 chr5:87968844 LOC645323 0.8 4.66 0.39 7.91e-6 Body mass index; TGCT cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs981844 1.000 rs55702511 chr4:154665978 A/C cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs40363 1.000 rs1635393 chr16:3520493 C/T cg22508957 chr16:3507546 NAT15 0.56 5.25 0.43 6.33e-7 Tuberculosis; TGCT cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.52 -5.85 -0.47 4.02e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs17767294 0.708 rs72848773 chr6:27926520 C/T cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs854765 0.964 rs12950562 chr17:17995166 C/T cg09796270 chr17:17721594 SREBF1 -0.26 -5.08 -0.41 1.37e-6 Total body bone mineral density; TGCT trans rs4650994 1.000 rs4650993 chr1:178515187 A/G cg05059571 chr16:84539110 KIAA1609 -0.41 -7.68 -0.57 4.07e-12 HDL cholesterol levels;HDL cholesterol; TGCT trans rs7618501 0.665 rs7621352 chr3:50070763 A/C cg21659725 chr3:3221576 CRBN -0.76 -9.35 -0.64 4.6e-16 Intelligence (multi-trait analysis); TGCT cis rs6138458 1.000 rs227624 chr20:24911562 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs9810089 0.903 rs711975 chr3:136235908 T/C cg12473912 chr3:136751656 NA 0.34 4.83 0.4 3.9e-6 Gestational age at birth (child effect); TGCT cis rs2777491 0.915 rs7165675 chr15:41614704 T/C cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.44 -0.68 1.07e-18 Ulcerative colitis; TGCT cis rs7954584 0.583 rs6486782 chr12:122359172 T/C cg22618164 chr12:122356400 WDR66 0.53 5.18 0.42 8.83e-7 Mean corpuscular volume; TGCT cis rs7191700 0.509 rs415595 chr16:11363692 A/G cg00044050 chr16:11439710 C16orf75 0.65 6.36 0.5 3.54e-9 Multiple sclerosis; TGCT cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs12615966 0.651 rs72830476 chr2:105414655 A/C cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs6121246 0.909 rs6089071 chr20:30378384 C/G cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs4455778 0.659 rs2041340 chr7:49023478 A/C cg26309511 chr7:48887640 NA -0.43 -5.13 -0.42 1.09e-6 Lung cancer in never smokers; TGCT cis rs4808199 0.947 rs1465695 chr19:19588546 A/C cg03709012 chr19:19516395 GATAD2A 0.97 7.53 0.56 9.28e-12 Nonalcoholic fatty liver disease; TGCT cis rs12477438 0.501 rs6542868 chr2:99782848 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs8180040 0.966 rs6790763 chr3:47572585 C/A cg27129171 chr3:47204927 SETD2 0.62 7.29 0.55 3.27e-11 Colorectal cancer; TGCT cis rs2836950 0.520 rs11911087 chr21:40665192 G/A cg11890956 chr21:40555474 PSMG1 -0.7 -6.76 -0.52 4.9e-10 Menarche (age at onset); TGCT cis rs4478858 0.684 rs2271074 chr1:31734841 C/T cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT trans rs2727020 0.681 rs2866362 chr11:49379316 A/G cg03929089 chr4:120376271 NA -0.74 -8.61 -0.61 2.73e-14 Coronary artery disease; TGCT cis rs5750830 0.621 rs743838 chr22:39824707 T/G cg24399712 chr22:39784796 NA -1.05 -12.52 -0.75 9.61e-24 Intelligence (multi-trait analysis); TGCT cis rs60871478 1.000 rs34086011 chr7:805430 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.6 0.38 1.04e-5 Cerebrospinal P-tau181p levels; TGCT cis rs769267 0.896 rs7250893 chr19:19625547 A/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs9467773 0.869 rs9295689 chr6:26455811 T/C cg26531700 chr6:26746687 NA 0.55 5.56 0.45 1.6e-7 Intelligence (multi-trait analysis); TGCT cis rs8051431 0.876 rs1559400 chr16:72011193 A/C cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT trans rs1496653 0.602 rs13100605 chr3:23325020 C/T cg02770683 chr12:57597238 LRP1 0.36 6.66 0.51 8.06e-10 Type 2 diabetes; TGCT cis rs765787 0.530 rs2554457 chr15:45520926 G/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.45 -0.44 2.66e-7 Uric acid levels; TGCT cis rs9611565 0.592 rs5996039 chr22:41981957 A/G cg13695892 chr22:41940480 POLR3H -0.83 -7.82 -0.57 1.94e-12 Vitiligo; TGCT cis rs72945132 0.882 rs6592554 chr11:70226040 G/A cg00319359 chr11:70116639 PPFIA1 1.03 7.86 0.58 1.59e-12 Coronary artery disease; TGCT cis rs2544527 0.586 rs1477253 chr2:15910457 T/C cg26669897 chr2:15909070 NA 0.44 5.49 0.44 2.19e-7 Pulmonary function (smoking interaction);Pulmonary function; TGCT trans rs7613875 0.620 rs11721204 chr3:49982765 C/T cg21659725 chr3:3221576 CRBN 0.66 7.37 0.55 2.1e-11 Body mass index; TGCT trans rs7726839 0.540 rs3762951 chr5:662613 C/G cg11887960 chr12:57824829 NA 1.14 9.88 0.66 2.52e-17 Obesity-related traits; TGCT cis rs7172971 0.576 rs8042219 chr15:42352153 A/G cg05886115 chr15:42349113 NA -0.32 -5.2 -0.42 8.03e-7 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs2303745 0.589 rs1965717 chr19:17398559 C/T cg02221750 chr19:17393354 ANKLE1 -0.46 -5.86 -0.47 3.98e-8 Systemic lupus erythematosus; TGCT cis rs7412746 0.658 rs12410394 chr1:150860186 G/A cg09365446 chr1:150670422 GOLPH3L 0.35 5.0 0.41 1.87e-6 Melanoma; TGCT cis rs5167 0.566 rs2075618 chr19:45495668 G/C cg09555818 chr19:45449301 APOC2 0.23 4.62 0.38 9.53e-6 Blood protein levels; TGCT cis rs9611565 0.500 rs2011053 chr22:42121278 G/A cg13695892 chr22:41940480 POLR3H 0.83 8.18 0.59 2.79e-13 Vitiligo; TGCT cis rs12681288 0.862 rs935821 chr8:1022455 G/A cg04851639 chr8:1020857 NA -0.39 -7.5 -0.56 1.08e-11 Schizophrenia; TGCT cis rs2836974 0.897 rs2026267 chr21:40711477 C/A cg17971929 chr21:40555470 PSMG1 0.91 8.16 0.59 3.18e-13 Cognitive function; TGCT cis rs7572733 0.514 rs700686 chr2:198721054 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs1801251 1.000 rs2592102 chr2:233726772 G/T cg08000102 chr2:233561755 GIGYF2 -0.64 -6.45 -0.5 2.24e-9 Coronary artery disease; TGCT cis rs9993613 0.875 rs4694124 chr4:73479251 A/G cg15102770 chr4:73434591 ADAMTS3 0.5 4.66 0.39 8.03e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs3099143 1.000 rs3099138 chr15:77115524 G/A cg21673338 chr15:77095150 SCAPER -0.52 -4.97 -0.41 2.15e-6 Recalcitrant atopic dermatitis; TGCT cis rs56104184 0.775 rs56149557 chr19:49401384 C/A cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2188554 0.785 rs11772396 chr7:117132919 C/T cg08576598 chr7:116962626 WNT2 0.38 4.88 0.4 3.13e-6 Esophageal adenocarcinoma; TGCT cis rs7568458 0.684 rs7608074 chr2:85809703 T/G cg17127132 chr2:85788382 GGCX 0.51 4.5 0.37 1.56e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3784262 1.000 rs11071356 chr15:58240518 T/G cg12031962 chr15:58353849 ALDH1A2 -0.47 -7.12 -0.54 7.85e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2997447 0.761 rs17257120 chr1:26450101 A/G cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT trans rs877282 0.838 rs34778553 chr10:796865 T/C cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg03609598 chr5:56110824 MAP3K1 -0.58 -4.66 -0.39 7.94e-6 Initial pursuit acceleration; TGCT cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg06238570 chr21:40685208 BRWD1 0.72 6.58 0.51 1.16e-9 Cognitive function; TGCT cis rs6598955 0.671 rs17257176 chr1:26578233 G/A cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs904251 0.523 rs2776920 chr6:37480605 G/A cg01843034 chr6:37503916 NA -0.55 -7.33 -0.55 2.54e-11 Cognitive performance; TGCT cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg11644478 chr21:40555479 PSMG1 0.99 10.5 0.69 7.73e-19 Cognitive function; TGCT cis rs2637266 1.000 rs7897348 chr10:78359620 G/A cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs2224391 0.518 rs116670419 chr6:5261263 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.03 -6.43 -0.5 2.47e-9 Height; TGCT cis rs9303401 0.614 rs35057477 chr17:57097064 G/A cg25039879 chr17:56429692 SUPT4H1 0.54 4.8 0.4 4.57e-6 Cognitive test performance; TGCT cis rs9993613 0.875 rs34975463 chr4:73490011 T/A cg15102770 chr4:73434591 ADAMTS3 0.5 4.59 0.38 1.05e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs1941023 0.503 rs7944025 chr11:60142538 C/A cg08716584 chr11:60157161 MS4A7 -0.34 -4.84 -0.4 3.81e-6 Congenital heart disease (maternal effect); TGCT cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs2120019 1.000 rs2120019 chr15:75334184 T/C cg17294928 chr15:75287854 SCAMP5 -0.78 -6.12 -0.48 1.14e-8 Blood trace element (Zn levels); TGCT cis rs2067615 0.542 rs4346064 chr12:107081599 C/A cg15890332 chr12:107067104 RFX4 0.29 5.73 0.46 7.31e-8 Heart rate; TGCT cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg22618164 chr12:122356400 WDR66 0.51 4.93 0.4 2.63e-6 Mean corpuscular volume; TGCT cis rs12540874 0.542 rs4947582 chr7:50566090 C/T cg18232548 chr7:50535776 DDC -0.35 -6.01 -0.48 1.89e-8 Systemic sclerosis; TGCT cis rs114540395 0.777 rs117550974 chr10:103166645 A/G cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs2404602 0.655 rs4886507 chr15:77209694 T/C cg26408565 chr15:76604113 ETFA -0.37 -4.62 -0.38 9.38e-6 Blood metabolite levels; TGCT cis rs7659604 0.539 rs3217773 chr4:122739121 A/G cg06713675 chr4:122721982 EXOSC9 -0.69 -9.7 -0.66 6.92e-17 Type 2 diabetes; TGCT cis rs6723226 0.638 rs6543657 chr2:32705085 T/C cg02381751 chr2:32503542 YIPF4 0.48 4.68 0.39 7.29e-6 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.554 rs75075857 chr7:1140298 C/T cg09177884 chr7:1199841 ZFAND2A -0.65 -5.18 -0.42 8.67e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs208515 0.525 rs9453538 chr6:66668508 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.9 9.56 0.65 1.46e-16 Exhaled nitric oxide levels; TGCT cis rs7044106 0.762 rs10818471 chr9:123394045 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 6.92 0.53 2.11e-10 Hip circumference adjusted for BMI; TGCT cis rs4819052 0.851 rs1056101 chr21:46678702 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.54 0.51 1.43e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6684514 0.885 rs12036837 chr1:156283895 A/C cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2075371 0.933 rs2544181 chr7:133944934 C/T cg11752832 chr7:134001865 SLC35B4 0.7 6.0 0.47 2.04e-8 Mean platelet volume; TGCT cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg02725872 chr8:58115012 NA -0.4 -4.87 -0.4 3.34e-6 Developmental language disorder (linguistic errors); TGCT trans rs28735056 0.904 rs35201860 chr18:77628719 T/C cg05926928 chr17:57297772 GDPD1 0.65 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs28595532 0.920 rs114659035 chr4:119740028 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6952808 0.792 rs12536261 chr7:1953571 G/A cg22963979 chr7:1858916 MAD1L1 -0.35 -5.4 -0.44 3.3e-7 Bipolar disorder and schizophrenia; TGCT cis rs3771570 1.000 rs55645375 chr2:242269024 A/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs11122272 0.735 rs2244986 chr1:231537452 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT cis rs7914558 1.000 rs1890184 chr10:104748459 A/C cg15744005 chr10:104629667 AS3MT -0.4 -4.91 -0.4 2.83e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs36051895 0.632 rs62541945 chr9:5161571 T/C cg02405213 chr9:5042618 JAK2 -0.71 -9.01 -0.63 3.02e-15 Pediatric autoimmune diseases; TGCT cis rs4642101 0.680 rs7626609 chr3:12806080 A/G cg05775895 chr3:12838266 CAND2 -0.68 -7.05 -0.53 1.11e-10 QRS complex (12-leadsum); TGCT cis rs4237845 0.715 rs4760340 chr12:58275176 A/T cg26785896 chr12:58013354 SLC26A10 -0.38 -4.66 -0.39 7.88e-6 Intelligence (multi-trait analysis); TGCT cis rs9952991 0.566 rs657555 chr18:12847136 C/T cg23544223 chr18:12777786 NA 0.57 5.0 0.41 1.87e-6 Inflammatory skin disease; TGCT cis rs597539 0.654 rs619727 chr11:68627535 A/G cg21963583 chr11:68658836 MRPL21 0.35 5.89 0.47 3.33e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3617 0.503 rs9866243 chr3:52915219 C/T cg10802521 chr3:52805072 NEK4 0.58 6.69 0.51 6.96e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1580019 0.522 rs10951340 chr7:32562408 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 14.68 0.8 6.88e-29 Cognitive ability; TGCT cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg24549020 chr5:56110836 MAP3K1 0.71 6.08 0.48 1.35e-8 Initial pursuit acceleration; TGCT cis rs42648 1.000 rs42648 chr7:89977760 A/G cg25739043 chr7:89950458 NA -0.67 -6.69 -0.51 6.97e-10 Homocysteine levels; TGCT cis rs68170813 0.559 rs75932578 chr7:106844694 C/T cg02696742 chr7:106810147 HBP1 -0.67 -5.3 -0.43 5.21e-7 Coronary artery disease; TGCT cis rs10986311 0.802 rs6478659 chr9:127128274 A/G cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.74 -0.39 5.86e-6 Vitiligo; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg07205460 chr22:24236375 MIF 0.58 4.49 0.37 1.62e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2841277 0.708 rs2582533 chr14:105398787 G/C cg19901468 chr14:105411992 AHNAK2 -0.27 -5.52 -0.44 1.89e-7 Rheumatoid arthritis; TGCT cis rs4975709 0.569 rs4975743 chr5:1859941 G/T cg07747251 chr5:1868357 NA 0.38 5.28 0.43 5.55e-7 Cardiovascular disease risk factors; TGCT cis rs17331151 0.541 rs4687676 chr3:52890418 C/T cg07884673 chr3:53033167 SFMBT1 -0.5 -5.82 -0.46 4.7e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1005277 0.579 rs2505257 chr10:38372664 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -7.87 -0.58 1.5e-12 Extrinsic epigenetic age acceleration; TGCT cis rs6504950 0.566 rs7226272 chr17:53046447 G/A cg19360675 chr17:53046073 COX11;STXBP4 0.56 5.41 0.44 3.06e-7 Breast cancer; TGCT cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs929354 0.772 rs933344 chr7:157011265 A/T cg05182265 chr7:156933206 UBE3C -0.41 -9.31 -0.64 5.91e-16 Body mass index; TGCT trans rs608114 1.000 rs591522 chr6:96378048 T/C cg04008557 chr11:2826328 KCNQ1 -0.65 -6.82 -0.52 3.51e-10 Response to abacavir-containing treatment in HIV-1 infection (virologic failure);Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs8180040 0.726 rs7625070 chr3:47095518 A/G cg27129171 chr3:47204927 SETD2 0.76 9.8 0.66 3.91e-17 Colorectal cancer; TGCT cis rs67385638 0.862 rs11036641 chr11:5310578 A/G cg12559170 chr11:5275217 HBG2 0.44 7.97 0.58 9.03e-13 Hemoglobin levels; TGCT cis rs801193 0.761 rs2659888 chr7:66230171 T/G cg00343986 chr7:65444356 GUSB 0.23 5.13 0.42 1.08e-6 Aortic root size; TGCT trans rs114540395 0.858 rs75204036 chr10:103248050 T/C cg10198749 chr1:39920707 MACF1 0.55 7.12 0.54 7.73e-11 Schizophrenia; TGCT cis rs4631830 0.720 rs2012677 chr10:51504797 T/A cg10326726 chr10:51549505 MSMB -0.23 -4.62 -0.38 9.64e-6 Prostate-specific antigen levels; TGCT cis rs7666738 0.830 rs13112037 chr4:98976986 A/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.654 rs4896829 chr6:145953675 T/A cg05347473 chr6:146136440 FBXO30 0.51 5.0 0.41 1.88e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11249608 0.548 rs11958355 chr5:178451640 T/C cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg09222892 chr1:25734099 RHCE -0.41 -6.72 -0.52 5.98e-10 Erythrocyte sedimentation rate; TGCT cis rs7666738 0.830 rs13110410 chr4:98920018 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.23 0.43 6.88e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg03609598 chr5:56110824 MAP3K1 -0.57 -4.5 -0.37 1.57e-5 Initial pursuit acceleration; TGCT cis rs6740322 0.895 rs6711966 chr2:43561989 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.32 -0.49 4.21e-9 Coronary artery disease; TGCT cis rs6565180 1.000 rs11862806 chr16:30364071 A/G cg17640201 chr16:30407289 ZNF48 -0.9 -8.94 -0.63 4.48e-15 Tonsillectomy; TGCT cis rs11252926 0.527 rs10904093 chr10:436848 A/G cg20256804 chr10:444983 DIP2C 0.2 4.46 0.37 1.83e-5 Psychosis in Alzheimer's disease; TGCT cis rs10114408 0.959 rs10761293 chr9:96645086 T/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs4901869 0.966 rs1820557 chr14:59334863 C/G cg02291164 chr14:59296302 NA 0.24 4.69 0.39 7.18e-6 Panic disorder; TGCT cis rs7027203 0.688 rs4075733 chr9:96624645 C/T cg13679303 chr9:96623674 NA -0.69 -11.4 -0.72 4.94e-21 DNA methylation (variation); TGCT cis rs1018836 0.923 rs2023626 chr8:91619264 G/T cg16814680 chr8:91681699 NA 0.84 8.65 0.61 2.28e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs796364 0.950 rs188146 chr2:200750444 C/T cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs2836950 0.545 rs4818001 chr21:40575088 T/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT cis rs2197308 0.765 rs11182434 chr12:37923968 C/A cg26384229 chr12:38710491 ALG10B 0.89 7.98 0.58 8.43e-13 Morning vs. evening chronotype; TGCT cis rs2932538 0.922 rs6681371 chr1:113101168 A/C cg22162597 chr1:113214053 CAPZA1 0.26 5.51 0.44 1.98e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs6089584 0.566 rs6061963 chr20:60607480 C/G cg13770153 chr20:60521292 NA -0.39 -4.67 -0.39 7.61e-6 Body mass index; TGCT cis rs4595586 0.545 rs7967295 chr12:39376866 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs904251 0.704 rs2776873 chr6:37483142 A/G cg01843034 chr6:37503916 NA -0.47 -5.12 -0.42 1.15e-6 Cognitive performance; TGCT cis rs7666738 0.830 rs7672720 chr4:98938760 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9303401 0.659 rs12150536 chr17:56640834 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs11031096 0.711 rs12270809 chr11:4206537 G/A cg18678763 chr11:4115507 RRM1 -0.45 -5.84 -0.46 4.31e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9486719 1.000 rs12190397 chr6:97036465 G/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs9467711 1.000 rs6903015 chr6:26322526 A/G cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2832191 0.740 rs2853830 chr21:30416824 A/G cg24692254 chr21:30365293 RNF160 0.99 11.67 0.72 1.1e-21 Dental caries; TGCT cis rs13424612 1.000 rs4149547 chr2:240933308 C/T cg26363272 chr2:240904871 NDUFA10 0.28 4.74 0.39 5.84e-6 Odorant perception (isobutyraldehyde); TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg02953382 chr22:24373134 LOC391322 -0.77 -8.01 -0.58 7.12e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1008375 1.000 rs11724495 chr4:17621310 G/A cg10189774 chr4:17578691 LAP3 0.59 5.28 0.43 5.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2832191 0.716 rs2249028 chr21:30365322 G/A cg08807101 chr21:30365312 RNF160 0.64 6.09 0.48 1.33e-8 Dental caries; TGCT cis rs642803 0.933 rs644740 chr11:65561468 C/T cg27068330 chr11:65405492 SIPA1 0.56 4.6 0.38 1.04e-5 Urate levels; TGCT cis rs11190604 1.000 rs4917901 chr10:102201773 A/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10791323 0.569 rs329664 chr11:133754975 G/T cg15485101 chr11:133734466 NA 0.38 5.49 0.44 2.13e-7 Childhood ear infection; TGCT cis rs7584330 0.554 rs3751105 chr2:238428459 G/A cg08992911 chr2:238395768 MLPH 0.67 4.52 0.38 1.41e-5 Prostate cancer; TGCT cis rs8077577 0.945 rs11654146 chr17:18076141 A/C cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs7582180 0.652 rs4851307 chr2:100971778 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.38e-6 Intelligence (multi-trait analysis); TGCT cis rs76935404 0.736 rs57274441 chr19:41431422 T/G cg19493303 chr19:41414353 NA 0.41 5.04 0.41 1.63e-6 nicotine metabolite ratio in current smokers; TGCT cis rs9916302 0.851 rs2338795 chr17:37399364 T/G cg07936489 chr17:37558343 FBXL20 -0.64 -5.18 -0.42 8.65e-7 Glomerular filtration rate (creatinine); TGCT cis rs3784262 1.000 rs4646640 chr15:58247563 C/G cg12031962 chr15:58353849 ALDH1A2 0.51 7.81 0.57 2.04e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs981844 1.000 rs17298985 chr4:154664261 C/T cg14289246 chr4:154710475 SFRP2 0.97 7.78 0.57 2.42e-12 Response to statins (LDL cholesterol change); TGCT cis rs10904908 1.000 rs10795465 chr10:17260525 C/T cg01003015 chr10:17271136 VIM -0.51 -4.44 -0.37 2.01e-5 Total cholesterol levels;Cholesterol, total; TGCT cis rs769267 0.896 rs10410664 chr19:19556651 G/A cg03709012 chr19:19516395 GATAD2A 0.76 6.42 0.5 2.64e-9 Tonsillectomy; TGCT cis rs1005224 1.000 rs1981898 chr14:76175565 C/A cg04684003 chr14:76127793 TTLL5;C14orf1 -0.69 -6.06 -0.48 1.54e-8 Large artery stroke; TGCT cis rs1018836 0.828 rs10091275 chr8:91559751 A/G cg16814680 chr8:91681699 NA -0.75 -7.83 -0.58 1.82e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg21724239 chr8:58056113 NA 0.48 5.17 0.42 9.18e-7 Developmental language disorder (linguistic errors); TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg11494091 chr17:61959527 GH2 0.59 12.62 0.75 5.45e-24 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs7669407 chr4:98750251 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1018836 0.770 rs12543806 chr8:91664011 C/T cg16814680 chr8:91681699 NA -0.96 -12.12 -0.74 8.65e-23 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6088580 0.634 rs4911418 chr20:32994257 G/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs8077889 0.763 rs4792913 chr17:41854497 T/C cg26893861 chr17:41843967 DUSP3 1.14 20.46 0.88 1.46e-41 Triglycerides; TGCT cis rs3818285 0.655 rs623980 chr10:111646147 C/T cg00817464 chr10:111662876 XPNPEP1 -0.32 -5.77 -0.46 5.9e-8 Superior crus of antihelix expression; TGCT cis rs8014204 0.967 rs1319171 chr14:75334096 G/T cg06637938 chr14:75390232 RPS6KL1 -0.77 -7.49 -0.56 1.14e-11 Caffeine consumption; TGCT trans rs17685 0.753 rs10476 chr7:75696420 C/T cg19862616 chr7:65841803 NCRNA00174 -0.49 -8.22 -0.59 2.25e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2243480 1.000 rs2420171 chr7:65637760 T/C cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs1153858 1.000 rs7169587 chr15:45640379 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg13395646 chr4:1353034 KIAA1530 -0.38 -4.72 -0.39 6.28e-6 Obesity-related traits; TGCT cis rs6831352 0.734 rs1311620 chr4:100013091 C/T cg12011299 chr4:100065546 ADH4 0.38 5.02 0.41 1.78e-6 Alcohol dependence; TGCT cis rs6903823 0.508 rs1233660 chr6:28260249 T/A cg18815343 chr6:28367644 ZSCAN12 -0.44 -4.65 -0.39 8.28e-6 Pulmonary function; TGCT cis rs7267979 1.000 rs7019 chr20:25278278 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6426558 0.502 rs10916080 chr1:227232040 A/G cg10327440 chr1:227177885 CDC42BPA 0.62 7.52 0.56 9.35e-12 Neutrophil percentage of white cells; TGCT cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8180040 0.620 rs6414435 chr3:47121140 A/G cg27129171 chr3:47204927 SETD2 0.71 8.55 0.61 3.9e-14 Colorectal cancer; TGCT cis rs367615 0.918 rs10070104 chr5:108866438 C/T cg17395555 chr5:108820864 NA -0.31 -5.01 -0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.11 13.91 0.78 4.47e-27 Height; TGCT cis rs57221529 0.766 rs72703070 chr5:590458 T/C cg09021430 chr5:549028 NA -0.38 -5.06 -0.41 1.45e-6 Lung disease severity in cystic fibrosis; TGCT cis rs17376456 0.825 rs13357713 chr5:93145423 T/C cg21475434 chr5:93447410 FAM172A 0.62 4.67 0.39 7.58e-6 Diabetic retinopathy; TGCT cis rs2594989 0.943 rs4684070 chr3:11437551 A/G cg00170343 chr3:11313890 ATG7 0.69 5.09 0.42 1.27e-6 Circulating chemerin levels; TGCT cis rs9549367 0.789 rs9549708 chr13:113891887 A/G cg00898013 chr13:113819073 PROZ -0.4 -4.98 -0.41 2.13e-6 Platelet distribution width; TGCT cis rs3749237 0.964 rs2352975 chr3:49891885 T/C cg07636037 chr3:49044803 WDR6 0.56 4.68 0.39 7.52e-6 Resting heart rate; TGCT cis rs112591243 0.685 rs117450955 chr21:47990916 T/A cg10657630 chr21:48055338 PRMT2 0.97 4.93 0.4 2.63e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT trans rs4332037 0.624 rs56256289 chr7:1892529 C/T cg10840412 chr1:235813424 GNG4 0.85 6.86 0.52 2.96e-10 Bipolar disorder; TGCT cis rs397020 0.904 rs203547 chr20:1195245 T/A cg16922058 chr20:1206700 RAD21L1 0.83 10.49 0.69 8.36e-19 Multiple sclerosis; TGCT cis rs3806843 0.706 rs2563302 chr5:140079051 T/C cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4722585 0.533 rs3753097 chr7:26198207 A/G cg07876897 chr7:26191696 NFE2L3 0.38 5.13 0.42 1.07e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs12134245 0.747 rs17501512 chr1:92012481 C/G cg25838465 chr1:92012736 NA 0.44 6.91 0.53 2.27e-10 Breast cancer; TGCT cis rs9796 0.621 rs691702 chr15:41474399 C/G cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.17 -0.54 5.94e-11 Menopause (age at onset); TGCT cis rs2456568 0.802 rs10765640 chr11:93636462 C/T cg14065697 chr11:93583672 C11orf90 -0.37 -4.63 -0.38 9.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs11098499 0.954 rs4345162 chr4:120312959 G/A cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg11644478 chr21:40555479 PSMG1 1.04 10.72 0.69 2.25e-19 Cognitive function; TGCT cis rs6860806 0.661 rs2136187 chr5:131577894 T/C cg24060327 chr5:131705240 SLC22A5 -0.58 -5.88 -0.47 3.48e-8 Breast cancer; TGCT cis rs9902453 0.619 rs2255489 chr17:28084974 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.72 -6.86 -0.52 2.93e-10 Coffee consumption (cups per day); TGCT cis rs10875746 0.669 rs10431526 chr12:48690143 A/G cg20731937 chr12:48336164 NA 0.61 4.65 0.39 8.23e-6 Longevity (90 years and older); TGCT cis rs67478160 0.634 rs2144080 chr14:104258761 A/C cg26031613 chr14:104095156 KLC1 -0.62 -6.19 -0.49 8.13e-9 Schizophrenia; TGCT cis rs317865 0.737 rs55949632 chr4:16207072 T/C cg04764131 chr4:16228633 TAPT1;FLJ39653 0.77 5.08 0.42 1.32e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs911263 0.961 rs1885013 chr14:68754695 G/A cg18825221 chr14:68749962 RAD51L1 0.28 5.57 0.45 1.52e-7 Primary biliary cholangitis; TGCT cis rs2729354 0.768 rs2584856 chr11:57267312 C/A cg24343310 chr11:57249947 NA 0.28 4.62 0.38 9.65e-6 Blood protein levels; TGCT cis rs9611565 0.512 rs6002474 chr22:42168181 A/G cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg14893161 chr1:205819251 PM20D1 0.66 10.84 0.7 1.13e-19 Menarche (age at onset); TGCT cis rs2469997 1.000 rs2447167 chr8:120366068 T/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs17539620 0.534 rs6557363 chr6:154827813 A/G cg17771515 chr6:154831774 CNKSR3 0.68 4.63 0.38 9.07e-6 Lipoprotein (a) levels; TGCT cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg17971929 chr21:40555470 PSMG1 0.68 6.04 0.48 1.64e-8 Cognitive function; TGCT cis rs1372520 0.684 rs2583979 chr4:90750588 A/T cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs11031096 0.711 rs10767881 chr11:4205122 C/G cg18678763 chr11:4115507 RRM1 -0.47 -6.04 -0.48 1.64e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7772486 0.790 rs2253764 chr6:146199881 T/A cg23711669 chr6:146136114 FBXO30 0.93 10.56 0.69 5.35e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs11122272 0.735 rs2486743 chr1:231506928 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs8062405 0.824 rs240702 chr16:28531353 C/T cg09754948 chr16:28834200 ATXN2L 0.57 4.48 0.37 1.67e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7829975 0.871 rs7829826 chr8:8578120 T/A cg06636001 chr8:8085503 FLJ10661 -0.6 -4.92 -0.4 2.73e-6 Mood instability; TGCT cis rs6500602 0.928 rs3747581 chr16:4462619 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.17 0.42 9.2e-7 Schizophrenia; TGCT cis rs4803468 1.000 rs878082 chr19:41897674 G/A cg09537434 chr19:41945824 ATP5SL -0.9 -10.15 -0.67 5.45e-18 Height; TGCT cis rs4509693 0.941 rs7914169 chr10:102495725 A/G cg24127310 chr10:102502104 NA 0.66 5.85 0.47 4.03e-8 Alzheimer's disease; TGCT cis rs12497850 0.931 rs4974082 chr3:48999323 G/A cg06212747 chr3:49208901 KLHDC8B 0.6 5.45 0.44 2.62e-7 Parkinson's disease; TGCT cis rs4319547 0.915 rs7966094 chr12:123115771 A/G cg23029597 chr12:123009494 RSRC2 -0.31 -5.16 -0.42 9.31e-7 Body mass index; TGCT cis rs57590327 0.503 rs2049415 chr3:81901887 A/T cg07356753 chr3:81810745 GBE1 -0.7 -6.42 -0.5 2.68e-9 Extraversion; TGCT cis rs904251 0.523 rs9369005 chr6:37483109 A/G cg08126542 chr6:37504118 NA -0.43 -6.22 -0.49 6.82e-9 Cognitive performance; TGCT cis rs4927850 1.000 rs7614767 chr3:195753451 C/T cg12923728 chr3:195709715 SDHAP1 -0.33 -7.26 -0.55 3.8e-11 Pancreatic cancer; TGCT cis rs478304 0.627 rs11227254 chr11:65454000 A/G cg27068330 chr11:65405492 SIPA1 -1.0 -11.14 -0.71 2.07e-20 Acne (severe); TGCT cis rs4478858 0.684 rs16834336 chr1:31751512 G/A cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs2288884 1.000 rs12609219 chr19:52580996 T/C cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT trans rs1814175 0.867 rs7926002 chr11:49616018 A/G cg03929089 chr4:120376271 NA -0.65 -7.45 -0.56 1.35e-11 Height; TGCT cis rs6951245 0.935 rs11766669 chr7:1063593 C/T cg18402987 chr7:1209562 NA 0.65 5.32 0.43 4.65e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1538970 0.924 rs12037201 chr1:45941349 G/T cg05343316 chr1:45956843 TESK2 0.75 6.2 0.49 7.66e-9 Platelet count; TGCT trans rs7726839 0.540 rs72703079 chr5:595173 T/C cg25482853 chr8:67687455 SGK3 1.26 10.61 0.69 4.22e-19 Obesity-related traits; TGCT cis rs7659604 0.539 rs11098646 chr4:122729301 T/C cg06713675 chr4:122721982 EXOSC9 -0.69 -9.69 -0.66 7.11e-17 Type 2 diabetes; TGCT cis rs6062302 0.540 rs2281926 chr20:62384309 G/C cg14758556 chr20:62440591 NA 0.36 4.8 0.4 4.57e-6 Glioblastoma; TGCT cis rs2153535 0.580 rs2184583 chr6:8447808 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs2836974 0.836 rs1041440 chr21:40627325 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.47 0.5 2.08e-9 Cognitive function; TGCT cis rs4803468 1.000 rs284656 chr19:41929251 T/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.57 -0.69 5.19e-19 Height; TGCT cis rs1008375 0.902 rs12503164 chr4:17656107 C/T cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7826238 0.601 rs2976907 chr8:8345168 C/T cg08975724 chr8:8085496 FLJ10661 0.61 5.93 0.47 2.78e-8 Systolic blood pressure; TGCT cis rs7914558 1.000 rs4917994 chr10:104811699 C/T cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.67e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2594989 0.779 rs2443701 chr3:11588773 C/T cg00170343 chr3:11313890 ATG7 -0.72 -5.29 -0.43 5.29e-7 Circulating chemerin levels; TGCT trans rs10506458 0.915 rs2013050 chr12:63394310 C/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs2404602 0.598 rs11634019 chr15:76634680 A/G cg17529965 chr15:77327887 PSTPIP1 0.3 4.43 0.37 2.01e-5 Blood metabolite levels; TGCT cis rs9911578 0.967 rs2567892 chr17:56668929 T/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs7662948 chr4:99020132 G/C cg17366294 chr4:99064904 C4orf37 0.66 6.55 0.51 1.35e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg03806693 chr22:41940476 POLR3H 1.04 10.57 0.69 5.2e-19 Vitiligo; TGCT cis rs826838 0.754 rs2387920 chr12:38626351 A/G cg13010199 chr12:38710504 ALG10B 0.65 5.15 0.42 9.92e-7 Heart rate; TGCT cis rs10791097 0.694 rs4436551 chr11:130755739 A/G cg12179176 chr11:130786555 SNX19 -0.81 -9.85 -0.66 2.99e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs79349575 0.783 rs17635252 chr17:47006950 T/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs62380364 0.602 rs448809 chr5:88005828 G/T cg22951263 chr5:87985283 NA -0.58 -6.22 -0.49 6.92e-9 Intelligence (multi-trait analysis); TGCT cis rs10501293 0.543 rs4272772 chr11:42989183 T/C cg03447554 chr11:43094025 NA 0.44 6.45 0.5 2.25e-9 Cognitive performance; TGCT cis rs1062177 0.756 rs2915827 chr5:151119705 T/A cg00977110 chr5:151150581 G3BP1 -0.4 -4.67 -0.39 7.7e-6 Preschool internalizing problems; TGCT cis rs9467773 1.000 rs2393670 chr6:26535541 A/G cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs4788570 0.566 rs8056735 chr16:71502483 A/G cg06353428 chr16:71660113 MARVELD3 -1.19 -7.74 -0.57 3.06e-12 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.501 rs6727749 chr2:99793590 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs6540559 0.673 rs6540560 chr1:209982073 A/G cg23283495 chr1:209979779 IRF6 -0.57 -5.03 -0.41 1.65e-6 Cleft lip with or without cleft palate; TGCT cis rs2836950 0.545 rs8132143 chr21:40584258 A/T cg11644478 chr21:40555479 PSMG1 -0.5 -4.7 -0.39 6.78e-6 Menarche (age at onset); TGCT cis rs908922 0.676 rs539393 chr1:152518896 C/T cg20991723 chr1:152506922 NA 0.45 6.09 0.48 1.33e-8 Hair morphology; TGCT cis rs875971 0.660 rs3764903 chr7:66098482 G/A cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs10905099 0.505 rs35832749 chr10:7079152 C/T cg20312131 chr10:7139482 NA 0.28 4.45 0.37 1.86e-5 Orofacial clefts; TGCT cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg05738196 chr6:26577821 NA 0.86 10.29 0.68 2.46e-18 Intelligence (multi-trait analysis); TGCT cis rs854765 0.624 rs12946746 chr17:17741669 T/C cg09796270 chr17:17721594 SREBF1 -0.27 -5.19 -0.42 8.39e-7 Total body bone mineral density; TGCT cis rs4523957 0.583 rs923864 chr17:2031507 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg24675658 chr1:53192096 ZYG11B -0.76 -8.67 -0.61 1.98e-14 Monocyte count; TGCT cis rs9486715 0.758 rs2971610 chr6:97027380 C/T cg06623918 chr6:96969491 KIAA0776 -1.1 -14.44 -0.79 2.5e-28 Headache; TGCT cis rs12134245 0.776 rs13447526 chr1:91983174 A/G cg02896835 chr1:92012615 NA 0.29 4.89 0.4 3.03e-6 Breast cancer; TGCT cis rs250677 0.522 rs4705302 chr5:148354962 G/C cg18129178 chr5:148520854 ABLIM3 0.36 4.62 0.38 9.43e-6 Breast cancer; TGCT cis rs17376456 0.877 rs10057814 chr5:93399092 C/G cg25358565 chr5:93447407 FAM172A 0.93 8.65 0.61 2.26e-14 Diabetic retinopathy; TGCT cis rs7584330 0.554 rs62186170 chr2:238425883 C/T cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs3135071 1.000 rs3135071 chr4:2406321 C/T cg08330972 chr4:2403930 ZFYVE28 0.58 4.92 0.4 2.72e-6 Influenza A (H1N1) severity; TGCT cis rs769267 0.895 rs2315279 chr19:19479936 C/A cg03709012 chr19:19516395 GATAD2A -0.78 -6.68 -0.51 7.12e-10 Tonsillectomy; TGCT cis rs11671005 0.735 rs3826683 chr19:58918733 T/C cg13877915 chr19:58951672 ZNF132 0.63 4.92 0.4 2.74e-6 Mean platelet volume; TGCT cis rs7172809 0.643 rs61483316 chr15:77834147 C/T cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.21e-6 Glucose homeostasis traits; TGCT cis rs11785400 1.000 rs4297023 chr8:143733307 C/A cg10596483 chr8:143751796 JRK 0.55 6.01 0.47 1.93e-8 Schizophrenia; TGCT cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg06697600 chr4:7070879 GRPEL1 -0.44 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs11190604 1.000 rs3793772 chr10:102222825 A/G cg16342193 chr10:102329863 NA -0.41 -5.44 -0.44 2.76e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9914544 0.545 rs4510081 chr17:18798846 A/C cg26378065 chr17:18585709 ZNF286B 0.51 4.6 0.38 1.03e-5 Educational attainment (years of education); TGCT cis rs763014 1.000 rs7205409 chr16:642610 A/G cg07343612 chr16:622815 PIGQ -0.35 -6.32 -0.49 4.23e-9 Height; TGCT cis rs11428934 1 rs11428934 chr19:49144245 T/TG cg07996880 chr19:49339085 HSD17B14 0.29 4.97 0.41 2.19e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;Granulocyte count; TGCT cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs7824557 0.527 rs2409756 chr8:11242025 A/C cg21775007 chr8:11205619 TDH -0.59 -5.62 -0.45 1.21e-7 Retinal vascular caliber; TGCT cis rs35306767 0.668 rs72760914 chr10:1070952 A/G cg26597838 chr10:835615 NA 0.51 5.94 0.47 2.71e-8 Eosinophil percentage of granulocytes; TGCT cis rs7474896 0.583 rs11011347 chr10:38019264 G/A cg25427524 chr10:38739819 LOC399744 -0.34 -5.47 -0.44 2.43e-7 Obesity (extreme); TGCT cis rs12615966 1.000 rs882424 chr2:105370336 C/A cg16465502 chr2:105461796 NA 0.76 4.5 0.37 1.57e-5 Pancreatic cancer; TGCT cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs7705042 0.865 rs7723666 chr5:141513966 C/T cg07392085 chr5:141489673 NDFIP1 0.32 4.69 0.39 7.12e-6 Asthma; TGCT cis rs7246967 0.673 rs6511383 chr19:22956900 C/T cg05241461 chr19:22816980 ZNF492 0.62 4.47 0.37 1.71e-5 Bronchopulmonary dysplasia; TGCT cis rs1670533 1.000 rs7669622 chr4:1058659 A/G cg20887711 chr4:1340912 KIAA1530 0.7 5.62 0.45 1.18e-7 Recombination rate (females); TGCT cis rs10875595 0.836 rs4912747 chr5:140676027 T/A cg20560182 chr5:140700478 TAF7 -0.64 -4.92 -0.4 2.7e-6 Pulmonary function decline; TGCT cis rs12477438 0.822 rs6727170 chr2:99588042 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.79 -6.91 -0.53 2.22e-10 Chronic sinus infection; TGCT cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611565 0.500 rs10775759 chr22:42088158 T/C cg06481639 chr22:41940642 POLR3H 0.73 6.62 0.51 9.76e-10 Vitiligo; TGCT cis rs6840360 0.615 rs72728173 chr4:152469373 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.74 -0.57 2.95e-12 Intelligence (multi-trait analysis); TGCT cis rs12510870 0.599 rs28450939 chr4:74450577 G/A cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg02725872 chr8:58115012 NA -0.39 -4.83 -0.4 3.9e-6 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.935 rs1827017 chr11:49632592 C/G cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs11642862 1.000 rs11645175 chr16:30803299 C/T cg02466173 chr16:30829666 NA -0.38 -4.57 -0.38 1.16e-5 Tonsillectomy; TGCT cis rs9733 0.596 rs12077833 chr1:150674333 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.81 0.4 4.38e-6 Tonsillectomy; TGCT cis rs12891047 1.000 rs7160196 chr14:68265744 C/T cg26938013 chr14:69015199 RAD51L1 0.45 4.54 0.38 1.32e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2836950 0.520 rs59916147 chr21:40634702 T/G cg17971929 chr21:40555470 PSMG1 -0.54 -4.87 -0.4 3.28e-6 Menarche (age at onset); TGCT cis rs28595532 0.920 rs114262028 chr4:119734877 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs208520 0.661 rs7766144 chr6:66827795 C/T cg07460842 chr6:66804631 NA -0.95 -9.74 -0.66 5.26e-17 Exhaled nitric oxide output; TGCT cis rs6121246 0.529 rs6120862 chr20:30199459 T/C cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs748404 0.690 rs2244981 chr15:43752751 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.71 0.39 6.65e-6 Lung cancer; TGCT cis rs6892003 0.857 rs58897526 chr5:174179812 C/T cg06056415 chr5:174162510 NA 0.44 4.62 0.38 9.46e-6 Clopidogrel active metabolite levels; TGCT cis rs57221529 0.713 rs12521091 chr5:590710 G/T cg09021430 chr5:549028 NA -0.44 -5.71 -0.46 7.94e-8 Lung disease severity in cystic fibrosis; TGCT cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg18402987 chr7:1209562 NA 0.67 5.94 0.47 2.72e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7044106 0.791 rs10985000 chr9:123484115 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.6 6.46 0.5 2.12e-9 Hip circumference adjusted for BMI; TGCT cis rs11098499 0.954 rs11098525 chr4:120390152 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs11676348 0.846 rs13009946 chr2:219007752 A/C cg00012203 chr2:219082015 ARPC2 -0.49 -4.62 -0.38 9.62e-6 Ulcerative colitis; TGCT cis rs1153858 1.000 rs8032904 chr15:45651309 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs12579753 0.869 rs12366920 chr12:82223015 G/A cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs6921919 0.583 rs2027361 chr6:28388308 A/G cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs921968 0.678 rs2230115 chr2:219509618 C/A cg02176678 chr2:219576539 TTLL4 0.37 5.2 0.42 7.81e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs11030122 0.702 rs10767713 chr11:3950157 T/C cg18678763 chr11:4115507 RRM1 -0.48 -5.99 -0.47 2.15e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs7010267 0.668 rs4563920 chr8:119993689 A/G cg17171407 chr8:119960777 TNFRSF11B 0.32 6.05 0.48 1.62e-8 Total body bone mineral density (age 45-60); TGCT cis rs1008375 0.800 rs10008598 chr4:17607323 T/C cg18681998 chr4:17616180 MED28 1.05 11.09 0.71 2.85e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12643440 0.538 rs2314602 chr4:17144535 A/G cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs12210905 1.000 rs12196889 chr6:27156095 G/C cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs1008375 1.000 rs2215450 chr4:17675394 T/G cg16339924 chr4:17578868 LAP3 0.6 5.14 0.42 1.05e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7681440 0.904 rs28415623 chr4:90767110 C/T cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg07870213 chr5:140052090 DND1 0.67 7.88 0.58 1.42e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg07138768 chr7:917805 C7orf20 0.45 5.63 0.45 1.14e-7 Perceived unattractiveness to mosquitoes; TGCT cis rs36051895 0.632 rs7469563 chr9:5139489 C/T cg02405213 chr9:5042618 JAK2 -0.73 -10.37 -0.68 1.59e-18 Pediatric autoimmune diseases; TGCT cis rs1801251 1.000 rs4973053 chr2:233670099 G/A cg08000102 chr2:233561755 GIGYF2 -0.64 -6.56 -0.51 1.28e-9 Coronary artery disease; TGCT trans rs804280 0.509 rs7461273 chr8:11777977 C/G cg15556689 chr8:8085844 FLJ10661 0.82 7.71 0.57 3.46e-12 Myopia (pathological); TGCT cis rs11098499 0.754 rs12510269 chr4:120241646 A/G cg09307838 chr4:120376055 NA 0.6 5.77 0.46 5.95e-8 Corneal astigmatism; TGCT cis rs7552404 0.924 rs12136754 chr1:76230232 C/A cg22875332 chr1:76189707 ACADM 0.74 8.9 0.62 5.76e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7772486 0.846 rs1854901 chr6:146325685 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.9 0.4 2.93e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs655029 0.837 rs3769631 chr2:31462373 C/A cg14018959 chr2:31480232 EHD3 -0.36 -4.88 -0.4 3.18e-6 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs8180040 0.620 rs17784127 chr3:47061700 T/C cg27129171 chr3:47204927 SETD2 -0.71 -8.51 -0.61 4.8e-14 Colorectal cancer; TGCT cis rs1218582 0.741 rs11264291 chr1:154914797 C/T cg09359103 chr1:154839909 KCNN3 -0.64 -11.86 -0.73 3.66e-22 Prostate cancer; TGCT cis rs17376456 0.597 rs10064158 chr5:93095186 C/T cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT cis rs2439831 1.000 rs689596 chr15:43761717 A/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs7819412 0.806 rs10113808 chr8:10926892 C/A cg21775007 chr8:11205619 TDH -0.49 -4.68 -0.39 7.45e-6 Triglycerides; TGCT cis rs4253772 0.744 rs9627278 chr22:46643432 C/G cg09491104 chr22:46646882 C22orf40 -0.49 -5.36 -0.43 3.95e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs875971 0.577 rs35072105 chr7:65609817 A/G cg00343986 chr7:65444356 GUSB -0.23 -5.12 -0.42 1.13e-6 Aortic root size; TGCT cis rs769267 0.930 rs2301786 chr19:19413947 A/G cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs8180040 0.966 rs17784882 chr3:47544003 C/A cg27129171 chr3:47204927 SETD2 -0.63 -7.18 -0.54 5.57e-11 Colorectal cancer; TGCT trans rs1496653 0.602 rs13073761 chr3:23390594 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1801251 1.000 rs283479 chr2:233648754 A/G cg08000102 chr2:233561755 GIGYF2 0.63 6.35 0.5 3.67e-9 Coronary artery disease; TGCT cis rs611744 0.647 rs11785776 chr8:109264933 C/T cg21045802 chr8:109455806 TTC35 0.7 7.23 0.54 4.3e-11 Dupuytren's disease; TGCT cis rs6089829 0.889 rs6062773 chr20:61663262 G/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs6901250 0.851 rs339307 chr6:117177340 A/G cg12892004 chr6:117198278 RFX6 -0.54 -6.63 -0.51 9.17e-10 C-reactive protein levels; TGCT cis rs12477438 0.520 rs7572660 chr2:99788582 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.54 0.61 4.06e-14 Chronic sinus infection; TGCT cis rs10927875 0.631 rs28579893 chr1:16347534 A/G cg22431228 chr1:16359049 CLCNKA -0.24 -4.51 -0.38 1.46e-5 Dilated cardiomyopathy; TGCT cis rs6088580 0.634 rs6088478 chr20:32971719 T/C cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs2153535 0.580 rs1577471 chr6:8485905 T/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs11122272 0.735 rs2790876 chr1:231536033 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT trans rs7819412 0.745 rs28591576 chr8:11080675 C/T cg06636001 chr8:8085503 FLJ10661 -0.77 -6.86 -0.52 2.93e-10 Triglycerides; TGCT cis rs921968 0.541 rs3755042 chr2:219317248 T/C cg02176678 chr2:219576539 TTLL4 -0.47 -6.78 -0.52 4.34e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs12477438 0.765 rs7605218 chr2:99593080 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs7681440 0.904 rs35424815 chr4:90767877 C/T cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs7772486 0.754 rs10872580 chr6:146140281 C/T cg13319975 chr6:146136371 FBXO30 0.55 5.01 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 1.000 rs4706254 chr6:86602813 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.1 -0.42 1.26e-6 Response to antipsychotic treatment; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg01238044 chr22:24384105 GSTT1 0.53 4.99 0.41 1.98e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9430161 0.645 rs6675082 chr1:11033797 T/C cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg06238570 chr21:40685208 BRWD1 0.69 6.38 0.5 3.27e-9 Cognitive function; TGCT cis rs892864 0.685 rs10041869 chr5:127739700 A/C cg01939274 chr5:127874478 FBN2 0.91 4.52 0.38 1.44e-5 Multiple system atrophy; TGCT cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg18654377 chr3:49208889 KLHDC8B 0.39 5.0 0.41 1.87e-6 Menarche (age at onset); TGCT cis rs921968 0.508 rs72965103 chr2:219312469 T/C cg02176678 chr2:219576539 TTLL4 -0.47 -6.78 -0.52 4.34e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs3806843 1.000 rs10477033 chr5:140169603 G/C cg19875535 chr5:140030758 IK 0.37 6.22 0.49 7.08e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs11098499 0.722 rs1814814 chr4:120258124 C/G cg09307838 chr4:120376055 NA 0.57 5.64 0.45 1.07e-7 Corneal astigmatism; TGCT cis rs7949030 0.596 rs11231137 chr11:62315699 G/A cg13298116 chr11:62369859 EML3;MTA2 0.6 7.14 0.54 6.96e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7523654 1.000 rs4565713 chr1:115869499 G/A cg07790079 chr1:116021925 NA -0.37 -4.71 -0.39 6.52e-6 Schizophrenia; TGCT cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg03517284 chr6:25882590 NA -0.5 -5.08 -0.41 1.37e-6 Height; TGCT cis rs12497850 0.931 rs9835307 chr3:48857805 T/C cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs7267979 0.933 rs2261109 chr20:25259200 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg03303774 chr4:1407052 NA 0.31 4.89 0.4 3.09e-6 Obesity-related traits; TGCT cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg23982607 chr1:1823379 GNB1 0.41 5.39 0.44 3.49e-7 Body mass index; TGCT cis rs7647973 0.626 rs1996663 chr3:49878264 C/G cg05785598 chr3:49045655 WDR6 -0.38 -4.44 -0.37 1.94e-5 Menarche (age at onset); TGCT cis rs909674 0.541 rs5750816 chr22:39810379 A/G cg24399712 chr22:39784796 NA 1.04 12.5 0.75 1.06e-23 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs67073037 0.955 rs4666133 chr2:29136623 T/C cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT trans rs6951245 0.638 rs4720486 chr7:1146764 G/A cg13565492 chr6:43139072 SRF -0.82 -7.87 -0.58 1.51e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2120019 1.000 rs12185102 chr15:75352201 G/A cg11632617 chr15:75315747 PPCDC -0.32 -4.67 -0.39 7.58e-6 Blood trace element (Zn levels); TGCT cis rs7666738 0.830 rs7684646 chr4:99071062 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.11 0.54 8.05e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.590 rs7606351 chr2:26292545 A/C cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs10504229 0.681 rs11779172 chr8:58045538 A/G cg08219700 chr8:58056026 NA 0.29 4.5 0.37 1.54e-5 Developmental language disorder (linguistic errors); TGCT cis rs2204008 0.774 rs12810027 chr12:38212165 A/G cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs10504229 0.906 rs113857287 chr8:58191683 T/C cg08219700 chr8:58056026 NA 0.3 4.48 0.37 1.66e-5 Developmental language disorder (linguistic errors); TGCT cis rs9790314 0.846 rs1478568 chr3:161014276 C/T cg03342759 chr3:160939853 NMD3 -0.48 -5.23 -0.43 6.93e-7 Morning vs. evening chronotype; TGCT cis rs950776 0.593 rs555018 chr15:78879242 G/A cg06917634 chr15:78832804 PSMA4 -0.67 -5.5 -0.44 2.07e-7 Sudden cardiac arrest; TGCT cis rs35306767 0.903 rs34847097 chr10:902252 A/T cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs308403 0.568 rs67050821 chr4:123674383 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.7 6.48 0.5 1.9e-9 Blood protein levels; TGCT cis rs7582180 0.764 rs7425797 chr2:100928337 T/C cg14675211 chr2:100938903 LONRF2 0.52 4.98 0.41 2.1e-6 Intelligence (multi-trait analysis); TGCT cis rs225245 0.817 rs2301730 chr17:33998683 A/G cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs2982552 0.844 rs2982559 chr6:152055905 G/A cg22157087 chr6:152012887 ESR1 0.21 5.16 0.42 9.59e-7 Bone properties (heel); TGCT cis rs2839186 0.739 rs7282763 chr21:47696800 C/T cg13732083 chr21:47605072 C21orf56 0.34 4.51 0.38 1.51e-5 Testicular germ cell tumor; TGCT cis rs11696501 0.739 rs6073815 chr20:44234615 A/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs28374715 0.578 rs10518717 chr15:41623368 C/G cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.83 -0.8 2.99e-29 Ulcerative colitis; TGCT cis rs6495367 1.000 rs745030 chr15:79381705 G/A cg17916960 chr15:79447300 NA 0.37 5.21 0.42 7.75e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs28595532 0.920 rs114575045 chr4:119739794 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2153535 0.580 rs763376 chr6:8492776 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2288884 0.806 rs59667666 chr19:52586194 A/G cg13540795 chr19:52551618 ZNF432 -0.61 -5.28 -0.43 5.48e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs6570726 0.791 rs6570694 chr6:145911204 C/G cg23711669 chr6:146136114 FBXO30 0.86 9.28 0.64 7.13e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs10193935 0.901 rs871045 chr2:42609431 G/C cg27598129 chr2:42591480 NA -0.41 -5.66 -0.45 1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg07617317 chr6:118971624 C6orf204 0.46 5.08 0.41 1.36e-6 Diastolic blood pressure; TGCT cis rs12530134 0.590 rs760492 chr6:170743989 A/G cg18217622 chr6:170732253 NA 0.72 4.68 0.39 7.37e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs68190844 1 rs68190844 chr17:4568953 CTA/C cg19197139 chr17:4613644 ARRB2 -0.87 -8.05 -0.59 5.79e-13 Eosinophil percentage of white cells; TGCT cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg21672276 chr3:44754072 ZNF502 -0.48 -5.43 -0.44 2.88e-7 Depressive symptoms; TGCT cis rs11190604 1.000 rs2298075 chr10:102247408 C/A cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs968451 0.901 rs5757584 chr22:39662550 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.8 6.83 0.52 3.41e-10 Primary biliary cholangitis; TGCT cis rs4704846 0.950 rs919746 chr5:156531316 C/T cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs2730260 0.537 rs55662704 chr7:158864184 T/C cg09066883 chr7:157932951 PTPRN2 0.41 4.52 0.38 1.41e-5 Myopia (pathological); TGCT trans rs28735056 1.000 rs28735056 chr18:77622879 A/G cg05926928 chr17:57297772 GDPD1 -0.67 -7.05 -0.53 1.08e-10 Schizophrenia; TGCT cis rs9318086 0.648 rs4067969 chr13:24469120 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.83 9.04 0.63 2.62e-15 Myopia (pathological); TGCT cis rs6912958 1.000 rs2207144 chr6:88150816 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.22 -0.49 7.06e-9 Monocyte percentage of white cells; TGCT cis rs3617 0.573 rs62253582 chr3:52928333 G/A cg10802521 chr3:52805072 NEK4 0.58 6.62 0.51 9.63e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9381040 0.599 rs2057001 chr6:41022947 A/G cg03526776 chr6:41159608 TREML2 0.27 5.29 0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg22166914 chr1:53195759 ZYG11B 0.37 6.37 0.5 3.34e-9 Monocyte count; TGCT cis rs7726839 0.526 rs11960158 chr5:568665 C/T cg09021430 chr5:549028 NA -0.42 -5.68 -0.45 9.25e-8 Obesity-related traits; TGCT cis rs9467773 0.869 rs742090 chr6:26415637 A/C cg05738196 chr6:26577821 NA -0.62 -6.65 -0.51 8.17e-10 Intelligence (multi-trait analysis); TGCT cis rs1008375 1.000 rs6818639 chr4:17633049 A/G cg18681998 chr4:17616180 MED28 1.01 11.55 0.72 2.15e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2933343 0.729 rs813945 chr3:128660937 A/G cg11901034 chr3:128598214 ACAD9 -0.64 -6.26 -0.49 5.66e-9 IgG glycosylation; TGCT cis rs6088580 0.634 rs4911151 chr20:32932273 T/C cg08999081 chr20:33150536 PIGU -0.26 -4.98 -0.41 2.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs2456568 0.867 rs72962810 chr11:93663619 A/G cg17595323 chr11:93583763 C11orf90 -0.46 -5.93 -0.47 2.77e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7267979 0.966 rs2424714 chr20:25418681 T/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2839186 0.868 rs2839199 chr21:47708269 T/C cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs950169 1.000 rs12916348 chr15:84765527 C/T cg17173187 chr15:85201210 NMB 0.47 5.23 0.43 7.01e-7 Schizophrenia; TGCT cis rs10411936 0.962 rs10404046 chr19:16477255 G/C cg14704714 chr19:15740395 CYP4F8 0.25 4.46 0.37 1.85e-5 White blood cell count;Multiple sclerosis; TGCT cis rs1150668 0.768 rs1150716 chr6:28262698 T/G cg11262757 chr6:27280423 POM121L2 0.46 4.62 0.38 9.52e-6 Pubertal anthropometrics; TGCT cis rs6570726 0.791 rs9403729 chr6:145907007 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.85 0.66 2.95e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6933660 0.760 rs3806982 chr6:151774916 G/A cg17179660 chr6:151773299 C6orf211;RMND1 -0.54 -4.88 -0.4 3.17e-6 Menarche (age at onset); TGCT cis rs10934753 0.632 rs4350878 chr3:125914214 C/G cg01346077 chr3:125931526 NA 0.44 7.17 0.54 6.06e-11 Plasma homocysteine levels (post-methionine load test); TGCT cis rs1669338 0.588 rs73005226 chr3:3195369 A/G cg16797762 chr3:3221439 CRBN -0.89 -5.74 -0.46 6.95e-8 White matter integrity; TGCT cis rs10504229 0.679 rs11783557 chr8:58030644 A/G cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs6901004 0.803 rs193282 chr6:111543067 G/A cg15721981 chr6:111408429 SLC16A10 -0.52 -4.55 -0.38 1.27e-5 Blood metabolite levels; TGCT cis rs459571 0.920 rs460154 chr9:136909309 C/T cg14405625 chr9:136855902 VAV2 -0.3 -4.46 -0.37 1.79e-5 Platelet distribution width; TGCT cis rs12579753 1.000 rs11613196 chr12:82173251 A/T cg07988820 chr12:82153109 PPFIA2 0.65 6.79 0.52 4.09e-10 Resting heart rate; TGCT cis rs1348850 0.539 rs1453371 chr2:178227862 T/G cg22681709 chr2:178499509 PDE11A -0.36 -4.51 -0.38 1.49e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs17665859 0.925 rs62484458 chr8:482717 T/C cg17960703 chr8:356704 FBXO25 1.2 4.7 0.39 6.74e-6 Bilirubin levels; TGCT cis rs78456975 0.546 rs72776254 chr2:1527881 C/T cg01028140 chr2:1542097 TPO -0.36 -4.61 -0.38 9.93e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs4242434 0.819 rs751680 chr8:22475627 G/A cg03733263 chr8:22462867 KIAA1967 1.06 16.43 0.83 6.43e-33 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs3858526 0.959 rs11039540 chr11:5928334 C/T cg13902645 chr11:5959945 NA -0.44 -4.8 -0.4 4.54e-6 DNA methylation (variation); TGCT cis rs6582630 0.519 rs1607868 chr12:38385512 G/T cg13010199 chr12:38710504 ALG10B 0.62 4.94 0.41 2.47e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4919694 1.000 rs76892505 chr10:104719290 G/A cg04362960 chr10:104952993 NT5C2 1.07 7.15 0.54 6.49e-11 Arsenic metabolism; TGCT cis rs6570726 0.738 rs6925594 chr6:145898454 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs904251 0.523 rs9366935 chr6:37480404 C/T cg25019722 chr6:37503610 NA -0.54 -7.82 -0.57 1.92e-12 Cognitive performance; TGCT cis rs2735413 0.564 rs73578735 chr16:78104936 C/G cg09132178 chr16:78079569 NA 0.35 4.72 0.39 6.29e-6 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs6089829 0.888 rs4809465 chr20:61671156 G/C cg03213289 chr20:61660250 NA 0.72 9.45 0.65 2.69e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs3935685 0.874 rs4334265 chr15:78007432 T/C cg03457338 chr15:78040120 NA -0.23 -6.08 -0.48 1.36e-8 Intelligence (multi-trait analysis); TGCT cis rs2663905 0.706 rs7162859 chr15:81360038 C/T cg18837035 chr15:81426597 C15orf26 0.8 6.82 0.52 3.59e-10 QT interval (drug interaction); TGCT cis rs11585357 0.895 rs72633808 chr1:17618665 A/G cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs6582630 0.555 rs10880612 chr12:38509427 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.86 0.58 1.55e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs9788333 0.788 rs35007728 chr13:21893221 G/C cg10411590 chr13:21900810 NA 0.35 4.44 0.37 1.98e-5 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs10791323 0.604 rs2250025 chr11:133710914 G/A cg03690763 chr11:133734501 NA -0.31 -4.79 -0.39 4.72e-6 Childhood ear infection; TGCT cis rs6565180 0.888 rs12921440 chr16:30408765 C/T cg17640201 chr16:30407289 ZNF48 1.03 9.96 0.67 1.61e-17 Tonsillectomy; TGCT trans rs7618501 0.522 rs73077175 chr3:49774658 G/A cg21659725 chr3:3221576 CRBN -0.68 -6.74 -0.52 5.33e-10 Intelligence (multi-trait analysis); TGCT cis rs4319547 0.656 rs1553179 chr12:122831073 A/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.68 -0.39 7.27e-6 Body mass index; TGCT cis rs4689592 0.503 rs10516184 chr4:7060959 C/T cg02503808 chr4:7069936 GRPEL1 0.89 7.17 0.54 5.92e-11 Monocyte percentage of white cells; TGCT cis rs425277 0.565 rs3128293 chr1:2065339 A/G cg03732007 chr1:2071316 PRKCZ -0.29 -6.49 -0.5 1.89e-9 Height; TGCT cis rs7772486 0.805 rs4896831 chr6:145959481 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.84 0.4 3.82e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs904251 0.861 rs1757173 chr6:37486952 A/C cg25019722 chr6:37503610 NA -0.5 -6.92 -0.53 2.17e-10 Cognitive performance; TGCT cis rs4595586 0.546 rs10876163 chr12:39244915 G/A cg13010199 chr12:38710504 ALG10B 0.6 4.72 0.39 6.26e-6 Morning vs. evening chronotype; TGCT cis rs7192750 0.586 rs9937936 chr16:71934419 A/T cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.11 13.91 0.78 4.47e-27 Height; TGCT cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg13397359 chr6:42928475 GNMT 0.72 6.47 0.5 2.07e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6912958 0.781 rs9450732 chr6:88249826 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs35146811 0.589 rs1727142 chr7:99816179 T/C cg22906224 chr7:99728672 NA -0.51 -4.49 -0.37 1.62e-5 Coronary artery disease; TGCT cis rs1538970 0.884 rs781226 chr1:45872662 T/C cg05343316 chr1:45956843 TESK2 -0.7 -5.46 -0.44 2.47e-7 Platelet count; TGCT cis rs4660261 0.526 rs2485996 chr1:44354661 C/T cg12908607 chr1:44402522 ARTN -0.66 -8.26 -0.6 1.85e-13 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.593 rs80174614 chr8:58024631 G/A cg08280861 chr8:58055591 NA 0.36 5.16 0.42 9.31e-7 Developmental language disorder (linguistic errors); TGCT cis rs6831352 0.879 rs29001196 chr4:100054116 C/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs1215050 0.791 rs1506438 chr4:98789542 C/T cg05340658 chr4:99064831 C4orf37 0.46 5.64 0.45 1.07e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg12667521 chr19:29218732 NA 0.55 5.84 0.46 4.36e-8 Methadone dose in opioid dependence; TGCT cis rs7666738 0.791 rs13120773 chr4:98972589 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.931 rs9682444 chr3:48852639 A/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs10875746 0.855 rs10875731 chr12:48432743 G/A cg20731937 chr12:48336164 NA 0.68 5.29 0.43 5.3e-7 Longevity (90 years and older); TGCT cis rs2580764 0.565 rs6545466 chr2:55228392 C/T cg09592903 chr2:55203963 RTN4 -0.25 -5.45 -0.44 2.58e-7 Mean platelet volume; TGCT cis rs9650657 0.740 rs12676417 chr8:10668634 C/T cg27411982 chr8:10470053 RP1L1 0.22 5.0 0.41 1.9e-6 Neuroticism; TGCT cis rs7914558 0.932 rs4307650 chr10:104959852 C/A cg15744005 chr10:104629667 AS3MT -0.39 -4.84 -0.4 3.83e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2469997 1.000 rs2470021 chr8:120362644 T/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs3027234 0.734 rs11650309 chr17:8129538 C/G cg08322244 chr17:8066669 VAMP2 -0.57 -5.53 -0.45 1.77e-7 Telomere length; TGCT cis rs346785 0.965 rs17509527 chr17:74286173 A/G cg09812376 chr17:74270190 QRICH2 -0.4 -6.14 -0.48 1.01e-8 White matter hyperintensities in ischemic stroke; TGCT cis rs3806843 0.900 rs2337984 chr5:140136811 G/A cg19875535 chr5:140030758 IK -0.36 -6.0 -0.47 2.05e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg23131131 chr22:24373011 LOC391322 -0.71 -7.38 -0.55 1.97e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4253772 0.550 rs6008762 chr22:46736228 T/C cg24881330 chr22:46731750 TRMU 0.99 5.31 0.43 4.99e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs3733585 0.673 rs4235347 chr4:9951956 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.65 -0.57 4.78e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs250677 1.000 rs250676 chr5:148425518 A/T cg18129178 chr5:148520854 ABLIM3 -0.42 -6.21 -0.49 7.23e-9 Breast cancer; TGCT cis rs7312933 0.501 rs3810793 chr12:42729407 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.16 0.42 9.38e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2997447 0.846 rs61775430 chr1:26411109 G/A cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs912057 0.632 rs1294429 chr6:6744652 G/A cg06612196 chr6:6737390 NA 0.47 6.77 0.52 4.57e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.49 5.08 0.41 1.38e-6 Lymphocyte counts; TGCT cis rs6684514 0.845 rs12138564 chr1:156291600 G/T cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1008375 0.932 rs6449315 chr4:17590219 A/G cg16339924 chr4:17578868 LAP3 0.83 7.21 0.54 4.92e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6459788 0.692 rs10807645 chr7:157258979 T/C cg03453431 chr7:157225567 NA 0.38 5.86 0.47 3.86e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs6430585 0.583 rs58509842 chr2:136586027 G/A cg07169764 chr2:136633963 MCM6 1.18 11.26 0.71 1.09e-20 Corneal structure; TGCT cis rs881375 1.000 rs10818480 chr9:123643170 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.47 0.44 2.33e-7 Rheumatoid arthritis; TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg24675658 chr1:53192096 ZYG11B -0.75 -9.12 -0.63 1.71e-15 Monocyte count; TGCT cis rs2836950 0.501 rs2070865 chr21:40715519 C/T cg11890956 chr21:40555474 PSMG1 -0.6 -5.53 -0.45 1.78e-7 Menarche (age at onset); TGCT cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg00786635 chr1:25594202 NA 0.6 6.25 0.49 6.14e-9 Erythrocyte sedimentation rate; TGCT cis rs11971779 0.938 rs28477480 chr7:139036058 C/T cg07862535 chr7:139043722 LUC7L2 -0.67 -4.83 -0.4 3.88e-6 Diisocyanate-induced asthma; TGCT cis rs9419702 0.568 rs7920966 chr10:133555185 G/T cg23460707 chr10:133558971 NA 0.41 4.68 0.39 7.46e-6 Survival in rectal cancer; TGCT cis rs929354 0.742 rs7807556 chr7:156934329 T/C cg05182265 chr7:156933206 UBE3C -0.38 -8.4 -0.6 8.9e-14 Body mass index; TGCT cis rs9911578 1.000 rs10401050 chr17:56953786 A/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT trans rs7726839 0.794 rs10474792 chr5:600058 G/A cg11887960 chr12:57824829 NA 0.97 7.56 0.56 7.58e-12 Obesity-related traits; TGCT cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg06238570 chr21:40685208 BRWD1 -0.69 -6.47 -0.5 2.03e-9 Cognitive function; TGCT cis rs636291 0.517 rs673254 chr1:10550352 C/T cg17425144 chr1:10567563 PEX14 0.54 7.52 0.56 9.62e-12 Prostate cancer; TGCT cis rs651907 0.535 rs61396602 chr3:101509046 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs25645 0.800 rs11078935 chr17:38192137 T/G cg17467752 chr17:38218738 THRA -0.59 -5.45 -0.44 2.55e-7 Myeloid white cell count; TGCT cis rs7523050 0.730 rs35100394 chr1:109433989 C/G cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs12681287 0.547 rs9942792 chr8:87509046 C/T cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg07507251 chr3:52567010 NT5DC2 0.49 6.88 0.53 2.67e-10 Bipolar disorder; TGCT cis rs910187 0.678 rs3818014 chr20:45816649 C/T cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs2228479 0.681 rs7199685 chr16:89959805 G/C cg06558623 chr16:89946397 TCF25 0.39 4.85 0.4 3.56e-6 Skin colour saturation; TGCT cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs290268 0.874 rs290991 chr9:93561450 A/C cg02608019 chr9:93564028 SYK -0.46 -4.71 -0.39 6.64e-6 Platelet count; TGCT cis rs1887596 0.663 rs2476713 chr13:27251602 A/G cg01312412 chr13:27282625 NA 0.27 4.76 0.39 5.31e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs3806843 0.576 rs246066 chr5:140323147 T/G cg09824255 chr5:140014002 CD14 0.25 4.48 0.37 1.68e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs13185784 0.667 rs6882940 chr5:179648989 A/G cg04734276 chr5:178882605 NA 0.29 4.52 0.38 1.42e-5 TRAIL levels; TGCT cis rs6940638 0.615 rs9393801 chr6:27242681 A/G cg26531700 chr6:26746687 NA -0.59 -5.16 -0.42 9.53e-7 Intelligence (multi-trait analysis); TGCT cis rs2412208 0.545 rs6685979 chr1:7067911 A/G cg09549827 chr1:6484616 ESPN 0.27 4.72 0.39 6.38e-6 Survival in sporadic amyotrophic lateral sclerosis; TGCT cis rs7666738 0.819 rs62318904 chr4:99036101 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.59 0.56 6.7e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6088590 0.610 rs6120663 chr20:33081906 A/C cg08999081 chr20:33150536 PIGU -0.27 -5.02 -0.41 1.75e-6 Coronary artery disease; TGCT cis rs881375 1.000 rs10117059 chr9:123653477 G/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.44 0.37 1.98e-5 Rheumatoid arthritis; TGCT cis rs1577917 0.771 rs9362233 chr6:86358247 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs9611519 1.000 rs9611505 chr22:41540279 T/C cg13695892 chr22:41940480 POLR3H -0.51 -4.57 -0.38 1.16e-5 Neuroticism; TGCT cis rs7666738 0.830 rs6833822 chr4:98951354 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1865760 0.566 rs3752419 chr6:26027433 C/T cg16482183 chr6:26056742 HIST1H1C 0.6 5.33 0.43 4.53e-7 Height; TGCT cis rs1129187 0.805 rs1053539 chr6:42903766 T/G cg09436375 chr6:42928200 GNMT -0.39 -5.13 -0.42 1.08e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7552404 1.000 rs7534754 chr1:76185308 G/A cg03433033 chr1:76189801 ACADM 0.83 9.83 0.66 3.18e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.57 -5.22 -0.42 7.14e-7 Prudent dietary pattern; TGCT cis rs9368481 0.729 rs10946881 chr6:26914611 C/T cg26531700 chr6:26746687 NA 0.7 6.44 0.5 2.43e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs853679 0.517 rs4713144 chr6:28106790 C/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT trans rs2688608 0.592 rs11000760 chr10:75493734 G/A cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs1552244 0.572 rs68013239 chr3:10165711 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs4383453 0.539 rs60870039 chr3:123101990 A/G cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs7044106 0.537 rs10739573 chr9:123489818 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 7.0 0.53 1.45e-10 Hip circumference adjusted for BMI; TGCT cis rs17401966 0.931 rs10864448 chr1:10277497 A/T cg19773385 chr1:10388646 KIF1B -0.22 -4.78 -0.39 4.96e-6 Hepatocellular carcinoma; TGCT cis rs909002 0.849 rs6663012 chr1:32091779 T/G cg11573219 chr1:32083031 HCRTR1 -0.46 -6.0 -0.47 2.01e-8 Intelligence (multi-trait analysis); TGCT cis rs939658 0.805 rs35291410 chr15:79438660 C/T cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs6840360 0.530 rs12645029 chr4:152650032 T/C cg17479576 chr4:152424074 FAM160A1 -0.66 -6.47 -0.5 2.02e-9 Intelligence (multi-trait analysis); TGCT cis rs6674176 0.628 rs7556565 chr1:44416090 C/T cg12908607 chr1:44402522 ARTN -0.68 -8.19 -0.59 2.7e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9467773 1.000 rs1884948 chr6:26567988 G/A cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.924 rs1303169 chr1:76195041 T/C cg10523679 chr1:76189770 ACADM 0.85 9.41 0.65 3.37e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2404602 0.710 rs2469541 chr15:76562118 C/T cg26408565 chr15:76604113 ETFA 0.52 6.98 0.53 1.59e-10 Blood metabolite levels; TGCT cis rs3733631 1.000 rs6533106 chr4:104596455 A/G cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT trans rs6089829 0.851 rs4809460 chr20:61661355 T/C cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs832540 0.931 rs832535 chr5:56213334 C/T cg12311346 chr5:56204834 C5orf35 -0.47 -4.97 -0.41 2.15e-6 Coronary artery disease; TGCT cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.754 rs9386132 chr6:146140751 T/C cg23711669 chr6:146136114 FBXO30 0.94 10.7 0.69 2.56e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs929354 1.000 rs929354 chr7:157045557 C/T cg05182265 chr7:156933206 UBE3C 0.28 5.99 0.47 2.1e-8 Body mass index; TGCT cis rs4783244 0.897 rs4783242 chr16:82651428 C/A cg09415485 chr16:82663111 CDH13 -0.24 -4.52 -0.38 1.4e-5 Adiponectin levels; TGCT trans rs2727020 0.729 rs10839268 chr11:49380328 G/A cg15704280 chr7:45808275 SEPT13 -0.74 -8.5 -0.61 5.01e-14 Coronary artery disease; TGCT cis rs7655841 0.704 rs11934740 chr4:129882748 C/T cg26347359 chr4:129759716 PHF17 0.4 4.55 0.38 1.25e-5 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs66561647 0.517 rs7819924 chr8:128914008 A/T cg11792826 chr8:129160931 MIR1208 0.2 4.48 0.37 1.67e-5 Hemoglobin concentration; TGCT cis rs6840360 1.000 rs4696284 chr4:152595836 C/G cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs6088580 0.634 rs6059868 chr20:33079460 A/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs1018836 0.923 rs6986001 chr8:91650205 T/C cg16814680 chr8:91681699 NA -0.83 -8.71 -0.62 1.62e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9916302 0.851 rs9904919 chr17:37556431 G/C cg07936489 chr17:37558343 FBXL20 0.65 4.98 0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.04 0.82 5e-32 Prudent dietary pattern; TGCT cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg03806693 chr22:41940476 POLR3H -1.15 -13.26 -0.77 1.52e-25 Vitiligo; TGCT cis rs1461503 0.966 rs1461502 chr11:122844927 C/G cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs116095464 0.614 rs4371799 chr5:268192 C/A cg22857025 chr5:266934 NA -0.34 -6.64 -0.51 8.6e-10 Breast cancer; TGCT cis rs295140 1.000 rs1367856 chr2:201160739 T/A cg04283868 chr2:201171347 SPATS2L 0.63 6.36 0.5 3.56e-9 QT interval; TGCT cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg17554472 chr22:41940697 POLR3H -0.48 -5.15 -0.42 9.89e-7 Vitiligo; TGCT cis rs10751667 0.666 rs7124480 chr11:971601 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.11 -0.59 4.14e-13 Alzheimer's disease (late onset); TGCT cis rs11098499 0.691 rs12510133 chr4:120271344 A/C cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.05e-7 Corneal astigmatism; TGCT trans rs17684571 0.938 rs35408048 chr6:56559544 G/T cg14229071 chr15:89282588 NA 0.52 6.74 0.52 5.33e-10 Schizophrenia; TGCT cis rs9549260 0.755 rs8001443 chr13:41216646 C/T cg21288729 chr13:41239152 FOXO1 -0.96 -10.19 -0.68 4.34e-18 Red blood cell count; TGCT cis rs6750047 0.567 rs336039 chr2:38258827 C/T cg07380506 chr2:38303506 CYP1B1 -0.57 -5.39 -0.44 3.49e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs61931739 0.500 rs7955933 chr12:34473608 A/G cg06521331 chr12:34319734 NA -0.27 -4.53 -0.38 1.37e-5 Morning vs. evening chronotype; TGCT cis rs611744 0.967 rs602384 chr8:109188185 G/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT trans rs7613875 0.521 rs4688754 chr3:50074641 G/T cg21659725 chr3:3221576 CRBN -0.67 -7.53 -0.56 9.05e-12 Body mass index; TGCT cis rs4711350 1.000 rs2182659 chr6:33751767 A/G cg00334056 chr6:33755658 LEMD2 -0.29 -4.61 -0.38 9.83e-6 Schizophrenia; TGCT cis rs2239547 0.522 rs2336162 chr3:52951519 C/T cg10802521 chr3:52805072 NEK4 0.6 5.85 0.47 4.1e-8 Schizophrenia; TGCT cis rs911555 0.755 rs975892 chr14:103883349 A/T cg23461800 chr14:103021989 NA 0.35 4.67 0.39 7.67e-6 Intelligence (multi-trait analysis); TGCT cis rs13326165 0.760 rs13075370 chr3:52399278 G/A cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.36e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs950776 0.518 rs11632604 chr15:78821914 T/C cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs60154123 0.505 rs7540237 chr1:210053325 C/T cg21951975 chr1:209979733 IRF6 0.64 4.77 0.39 5.12e-6 Coronary artery disease; TGCT cis rs748404 0.631 rs12905772 chr15:43648444 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs28595532 0.841 rs56388366 chr4:119769242 A/G cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs3935685 0.874 rs4334265 chr15:78007432 T/C cg25212270 chr15:78015279 NA 0.26 5.49 0.44 2.14e-7 Intelligence (multi-trait analysis); TGCT cis rs250677 0.687 rs36046 chr5:148441257 A/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs13256369 0.756 rs13282580 chr8:8562903 C/T cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs6545883 0.718 rs3771260 chr2:61762384 G/T cg15711740 chr2:61764176 XPO1 -0.57 -5.29 -0.43 5.32e-7 Tuberculosis; TGCT cis rs3784262 1.000 rs4646638 chr15:58248783 C/T cg12031962 chr15:58353849 ALDH1A2 0.52 7.91 0.58 1.22e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1245541 0.595 rs11818980 chr10:73872574 C/T cg10983208 chr10:73848320 SPOCK2 -0.26 -4.48 -0.37 1.7e-5 Insulin-like growth factors; TGCT cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.27 0.49 5.58e-9 Mean platelet volume; TGCT cis rs7249142 0.549 rs2238667 chr19:19282523 G/A cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.55 0.45 1.63e-7 IgG glycosylation; TGCT cis rs12142240 0.621 rs13374968 chr1:46843908 T/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.79 -0.4 4.69e-6 Menopause (age at onset); TGCT cis rs6725041 0.547 rs1505353 chr2:213203057 C/A cg20637307 chr2:213403960 ERBB4 -0.54 -4.51 -0.38 1.51e-5 QT interval (ambient particulate matter interaction); TGCT cis rs9341808 0.754 rs3805925 chr6:80883833 T/C cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs9368481 0.678 rs62402024 chr6:26923976 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 0.47 5.04 0.41 1.62e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg00024416 chr22:24240387 NA 0.36 6.11 0.48 1.19e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs11264213 0.901 rs72661640 chr1:36447232 T/G cg27506609 chr1:36549197 TEKT2 0.41 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs950169 0.922 rs4842946 chr15:84942331 G/A cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs3733585 0.699 rs6834893 chr4:9959123 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1790761 0.501 rs4930210 chr11:67404726 G/T cg14500267 chr11:67383377 NA -0.31 -4.83 -0.4 3.97e-6 Mean corpuscular volume; TGCT cis rs6912958 0.712 rs6908386 chr6:88354746 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs7312933 0.533 rs3747557 chr12:42717961 G/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.7 -0.46 8.16e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs597539 0.652 rs622082 chr11:68703959 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.82 7.52 0.56 9.42e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs35306767 0.951 rs61833265 chr10:990143 C/T cg26597838 chr10:835615 NA 0.62 8.25 0.6 1.94e-13 Eosinophil percentage of granulocytes; TGCT cis rs9303401 0.614 rs62084384 chr17:57126842 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.8 0.46 5.11e-8 Cognitive test performance; TGCT cis rs751728 0.626 rs4711348 chr6:33736295 G/A cg13859433 chr6:33739653 LEMD2 -0.33 -6.03 -0.48 1.72e-8 Crohn's disease; TGCT cis rs478304 0.593 rs7120713 chr11:65483374 G/C cg27068330 chr11:65405492 SIPA1 -0.96 -9.18 -0.64 1.19e-15 Acne (severe); TGCT cis rs7103648 0.897 rs3758675 chr11:47400602 G/A cg20307385 chr11:47447363 PSMC3 1.05 12.13 0.74 8.16e-23 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs7944584 0.563 rs61895112 chr11:47560433 T/C cg20307385 chr11:47447363 PSMC3 0.9 8.49 0.61 5.41e-14 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs9291683 0.655 rs35750364 chr4:10049049 T/C cg00071950 chr4:10020882 SLC2A9 0.68 8.66 0.61 2.13e-14 Bone mineral density; TGCT cis rs11578119 0.689 rs6665215 chr1:170392281 A/G cg09767346 chr1:170501363 GORAB -0.57 -4.7 -0.39 6.94e-6 Male-pattern baldness; TGCT cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg00484396 chr16:3507460 NAT15 0.43 6.62 0.51 9.89e-10 Tuberculosis; TGCT cis rs1127311 0.846 rs61811388 chr1:154581231 G/C cg17218026 chr1:154582156 ADAR 0.31 7.76 0.57 2.66e-12 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs9300255 0.739 rs4759415 chr12:123743674 C/T cg00376283 chr12:123451042 ABCB9 -0.72 -5.54 -0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs1552244 0.554 rs17050704 chr3:10045734 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs1218582 0.711 rs4845677 chr1:154838050 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.66 -6.6 -0.51 1.09e-9 Prostate cancer; TGCT cis rs7659604 0.643 rs6838881 chr4:122663616 A/T cg19748678 chr4:122722346 EXOSC9 0.56 4.86 0.4 3.43e-6 Type 2 diabetes; TGCT cis rs992157 1.000 rs10932766 chr2:219122090 G/A cg00012203 chr2:219082015 ARPC2 0.77 8.2 0.59 2.56e-13 Colorectal cancer; TGCT cis rs2594989 0.733 rs6779007 chr3:11583254 C/T cg00170343 chr3:11313890 ATG7 -0.66 -5.1 -0.42 1.23e-6 Circulating chemerin levels; TGCT cis rs1008375 0.932 rs10009933 chr4:17670107 A/C cg18681998 chr4:17616180 MED28 0.87 9.09 0.63 1.95e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10789285 0.681 rs2249229 chr1:69701433 T/C ch.1.69469992R chr1:69697404 NA 0.3 4.46 0.37 1.82e-5 Psoriasis; TGCT cis rs12134133 1.000 rs2661357 chr1:207483938 A/T cg02152968 chr1:207494213 CD55 0.57 4.52 0.38 1.43e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7208859 0.673 rs999797 chr17:29159329 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.65 -0.39 8.38e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs597539 0.615 rs629426 chr11:68671104 A/G cg21862992 chr11:68658383 NA 0.46 6.54 0.51 1.45e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28595532 0.764 rs115011450 chr4:119778171 C/T cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs6912958 0.535 rs448580 chr6:88040399 A/C cg12350822 chr6:88032061 C6orf162;GJB7 0.45 5.95 0.47 2.59e-8 Monocyte percentage of white cells; TGCT cis rs11122272 0.525 rs2739517 chr1:231537914 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.97 -12.73 -0.75 2.98e-24 Prudent dietary pattern; TGCT cis rs986417 1.000 rs1956549 chr14:60928201 G/A cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Vitiligo; TGCT cis rs611744 0.901 rs655320 chr8:109197482 T/A cg21045802 chr8:109455806 TTC35 0.5 4.5 0.37 1.53e-5 Dupuytren's disease; TGCT cis rs7582180 0.629 rs11694642 chr2:100957813 A/G cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.629 rs11684516 chr2:100949883 C/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs9921338 0.961 rs9936093 chr16:11437316 C/G cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.32e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs10934753 0.632 rs1447661 chr3:125924981 A/G cg01346077 chr3:125931526 NA 0.37 6.11 0.48 1.21e-8 Plasma homocysteine levels (post-methionine load test); TGCT cis rs1865760 0.963 rs3846838 chr6:25911775 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs9368481 0.594 rs2636425 chr6:26799460 A/G cg26531700 chr6:26746687 NA 0.7 6.48 0.5 2e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs78456975 0.941 rs28913033 chr2:1523194 T/C cg01028140 chr2:1542097 TPO -0.35 -4.67 -0.39 7.82e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs11731606 0.508 rs6828270 chr4:95309212 G/A cg00507259 chr4:95128692 SMARCAD1 0.6 4.45 0.37 1.88e-5 Mean platelet volume; TGCT cis rs9807989 0.524 rs2110662 chr2:103020139 A/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.37 4.74 0.39 5.7e-6 Lymphocyte counts; TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg24675658 chr1:53192096 ZYG11B -0.81 -9.94 -0.67 1.76e-17 Monocyte count; TGCT cis rs9788682 1.000 rs12438181 chr15:78812098 G/A cg24631222 chr15:78858424 CHRNA5 0.91 7.98 0.58 8.29e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2070488 0.745 rs7649153 chr3:38467753 T/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.66 5.14 0.42 1.02e-6 Electrocardiographic conduction measures; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg18538332 chr22:24372958 LOC391322 -1.01 -12.94 -0.76 9.13e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs35306767 0.903 rs12769873 chr10:936526 G/T cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs56104184 0.723 rs73063524 chr19:49409004 T/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs3862435 0.610 rs2589942 chr15:90935181 T/C cg00487526 chr15:90818384 NA -0.39 -4.65 -0.39 8.28e-6 Response to exercise (triglyceride level interaction); TGCT cis rs4455778 0.580 rs7455537 chr7:49076576 G/A cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.07e-9 Lung cancer in never smokers; TGCT cis rs9302065 0.866 rs75006318 chr13:95968259 T/G cg24476569 chr13:95954382 ABCC4 -0.44 -6.57 -0.51 1.26e-9 Blood metabolite levels; TGCT cis rs9916302 0.851 rs4794810 chr17:37603774 T/C cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs1933488 0.804 rs9397586 chr6:153414287 C/A cg24028809 chr6:153414101 RGS17 0.2 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs6901250 1.000 rs993394 chr6:117117143 G/A cg12892004 chr6:117198278 RFX6 0.46 5.13 0.42 1.07e-6 C-reactive protein levels; TGCT cis rs67072384 1.000 rs7120605 chr11:72444615 A/G cg03713592 chr11:72463424 ARAP1 -0.9 -4.63 -0.38 9.26e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs7552404 0.855 rs385897 chr1:76106962 T/C cg22875332 chr1:76189707 ACADM -0.79 -9.72 -0.66 6.2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg03517284 chr6:25882590 NA -1.13 -14.86 -0.8 2.55e-29 Urate levels; TGCT cis rs367615 0.840 rs113540823 chr5:108879084 C/T cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6897795 0.680 rs9329133 chr5:177609540 C/T cg13600420 chr5:177614205 GMCL1L 0.5 4.66 0.39 7.92e-6 Plateletcrit; TGCT cis rs3096299 0.967 rs28689480 chr16:89460093 T/C cg06640241 chr16:89574553 SPG7 0.62 5.89 0.47 3.38e-8 Multiple myeloma (IgH translocation); TGCT cis rs9467773 1.000 rs1535277 chr6:26567802 G/T cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs35194639 chr4:99053819 G/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10746514 1.000 rs10746514 chr1:232246027 G/A cg09506761 chr1:232265262 NA 0.5 5.11 0.42 1.17e-6 Response to statin therapy; TGCT trans rs1814175 0.935 rs28586931 chr11:49693872 G/A cg03929089 chr4:120376271 NA -0.63 -7.0 -0.53 1.41e-10 Height; TGCT cis rs6569992 0.636 rs62429819 chr6:135490468 A/T cg22676075 chr6:135203613 NA 0.74 5.03 0.41 1.69e-6 Red blood cell traits; TGCT cis rs17401966 0.838 rs2182326 chr1:10385664 G/A cg19773385 chr1:10388646 KIF1B -0.23 -5.45 -0.44 2.63e-7 Hepatocellular carcinoma; TGCT cis rs6540559 0.546 rs735694 chr1:210034029 T/C cg04352962 chr1:209979756 IRF6 0.69 4.73 0.39 6.04e-6 Cleft lip with or without cleft palate; TGCT cis rs7777484 0.517 rs2644306 chr7:2831602 A/G cg25467336 chr7:2757616 NA -0.26 -4.78 -0.39 4.92e-6 Height; TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg14893161 chr1:205819251 PM20D1 0.53 7.38 0.55 1.98e-11 Monocyte percentage of white cells; TGCT cis rs3015497 0.554 rs8011039 chr14:51091267 C/T cg04730355 chr14:51134070 SAV1 -0.67 -6.35 -0.5 3.64e-9 Mean platelet volume; TGCT cis rs11112613 0.713 rs11112591 chr12:105951620 C/T cg03607813 chr12:105948248 NA 0.49 5.88 0.47 3.53e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs6582630 0.519 rs4436613 chr12:38293653 T/C cg13010199 chr12:38710504 ALG10B 0.57 4.49 0.37 1.62e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs875971 0.660 rs801192 chr7:66031952 C/G cg00343986 chr7:65444356 GUSB -0.24 -5.29 -0.43 5.43e-7 Aortic root size; TGCT cis rs3784262 0.669 rs17820990 chr15:58349568 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs854765 0.624 rs1889018 chr17:17734740 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.67 -0.51 7.5e-10 Total body bone mineral density; TGCT cis rs59197085 0.591 rs73238120 chr7:128432108 C/T cg00260937 chr7:128520193 KCP 0.44 4.73 0.39 6.07e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs654950 0.934 rs641974 chr1:42002137 G/A cg06885757 chr1:42089581 HIVEP3 -0.26 -4.6 -0.38 1.01e-5 Airway imaging phenotypes; TGCT cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.11 13.91 0.78 4.47e-27 Height; TGCT cis rs9818758 0.607 rs113186424 chr3:49272726 T/C cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs3741151 1.000 rs3741149 chr11:73021084 A/G cg17517138 chr11:73019481 ARHGEF17 -1.04 -5.36 -0.43 3.97e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs17331151 0.573 rs79664140 chr3:52866936 A/G cg27565382 chr3:53032988 SFMBT1 0.47 5.96 0.47 2.42e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs60843830 0.661 rs7588043 chr2:104979 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.62 5.52 0.44 1.92e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 5.53 0.45 1.78e-7 Alzheimer's disease; TGCT cis rs637571 0.522 rs12797319 chr11:65735672 G/A cg17985854 chr11:65770987 BANF1;EIF1AD 0.21 4.49 0.37 1.61e-5 Eosinophil percentage of white cells; TGCT cis rs17376456 0.825 rs13171131 chr5:93223028 C/T cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.17e-13 Diabetic retinopathy; TGCT cis rs2072499 0.750 rs57056972 chr1:156159064 C/A cg24450063 chr1:156163899 SLC25A44 1.11 10.16 0.67 5.03e-18 Testicular germ cell tumor; TGCT trans rs7726839 0.526 rs55647623 chr5:567747 T/C cg25482853 chr8:67687455 SGK3 1.1 8.74 0.62 1.34e-14 Obesity-related traits; TGCT cis rs3820928 0.845 rs4234065 chr2:227882006 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.94 -0.41 2.51e-6 Pulmonary function; TGCT cis rs12291225 0.546 rs11023199 chr11:14394258 A/G cg19336497 chr11:14380999 RRAS2 -0.46 -7.39 -0.55 1.87e-11 Sense of smell; TGCT cis rs9677476 0.516 rs2303350 chr2:232030555 G/A cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs61990749 0.597 rs3783980 chr14:78219807 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs1532993 0.518 rs10003706 chr4:98573238 G/C cg05340658 chr4:99064831 C4orf37 -0.38 -4.53 -0.38 1.36e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9325144 0.600 rs11183505 chr12:38759110 G/T cg26384229 chr12:38710491 ALG10B -0.62 -5.77 -0.46 5.9e-8 Morning vs. evening chronotype; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg25767906 chr1:53392781 SCP2 -0.53 -6.21 -0.49 7.34e-9 Monocyte count; TGCT cis rs11190604 1.000 rs2295776 chr10:102295629 G/T cg16342193 chr10:102329863 NA -0.41 -5.37 -0.43 3.78e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6500602 0.627 rs934929 chr16:4587789 A/G cg08645402 chr16:4508243 NA -0.21 -5.51 -0.44 2e-7 Schizophrenia; TGCT cis rs7223966 1.000 rs56383601 chr17:61929968 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3772130 1.000 rs11719458 chr3:121382005 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.55 5.06 0.41 1.45e-6 Cognitive performance; TGCT cis rs2242116 0.896 rs724448 chr3:46935734 A/C cg02527881 chr3:46936655 PTH1R -0.3 -5.77 -0.46 5.91e-8 Birth weight; TGCT cis rs709400 0.663 rs62007687 chr14:103903763 G/T cg26031613 chr14:104095156 KLC1 0.86 9.43 0.65 2.96e-16 Body mass index; TGCT cis rs7043114 0.525 rs7869742 chr9:95256174 A/G cg14631576 chr9:95140430 CENPP -0.28 -4.61 -0.38 9.88e-6 Height; TGCT cis rs9814567 0.896 rs4245907 chr3:134347876 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.8 -7.29 -0.55 3.14e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs13191362 1.000 rs13204439 chr6:163015358 A/C cg06582575 chr6:163149167 PACRG;PARK2 -0.57 -4.94 -0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7659604 0.521 rs4833234 chr4:122694799 T/C cg06713675 chr4:122721982 EXOSC9 0.35 4.48 0.37 1.7e-5 Type 2 diabetes; TGCT cis rs7552404 0.731 rs10873788 chr1:76367857 A/C cg10523679 chr1:76189770 ACADM 0.79 6.8 0.52 4.01e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg12419862 chr22:24373484 LOC391322 -0.79 -8.23 -0.59 2.19e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17152411 0.709 rs1896530 chr10:126581925 A/T cg07906193 chr10:126599966 NA -0.32 -4.52 -0.38 1.42e-5 Height; TGCT cis rs7617773 0.539 rs11706939 chr3:48383992 G/T cg11946769 chr3:48343235 NME6 0.57 4.83 0.4 4.01e-6 Coronary artery disease; TGCT cis rs6951245 0.638 rs4720486 chr7:1146764 G/A cg03188948 chr7:1209495 NA 0.5 5.27 0.43 5.87e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1903068 0.752 rs28517654 chr4:55993468 T/C cg09978860 chr4:56023921 NA 0.55 6.09 0.48 1.31e-8 Endometriosis; TGCT cis rs13256369 0.851 rs11249890 chr8:8565245 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs807669 0.934 rs1780643 chr22:19191725 T/C cg02655711 chr22:19163373 SLC25A1 0.4 9.27 0.64 7.35e-16 Metabolite levels; TGCT cis rs78487399 0.908 rs74854268 chr2:43844079 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.58 0.38 1.12e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1801251 0.963 rs7562712 chr2:233606580 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs611744 0.967 rs685690 chr8:109192145 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs6688613 1.000 rs7554962 chr1:166956297 C/T cg07049167 chr1:166818506 POGK 0.21 4.52 0.38 1.43e-5 Refractive astigmatism; TGCT cis rs12136530 0.636 rs4244001 chr1:19734368 C/T cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs2303745 0.640 rs10403581 chr19:17384192 A/C cg02221750 chr19:17393354 ANKLE1 -0.49 -6.34 -0.5 3.81e-9 Systemic lupus erythematosus; TGCT cis rs2153535 0.580 rs1414348 chr6:8471940 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7829975 0.564 rs2976855 chr8:8301794 G/A cg06636001 chr8:8085503 FLJ10661 0.73 7.08 0.54 9.63e-11 Mood instability; TGCT cis rs2933343 0.951 rs789217 chr3:128593201 C/T cg11901034 chr3:128598214 ACAD9 -0.64 -4.95 -0.41 2.39e-6 IgG glycosylation; TGCT cis rs9467773 0.804 rs2073526 chr6:26374658 C/T cg14124522 chr6:26610872 NA 0.17 4.48 0.37 1.7e-5 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.938 rs6742226 chr2:26342537 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg15242686 chr22:24348715 GSTTP1 -0.49 -7.1 -0.54 8.64e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3771570 0.901 rs73008106 chr2:242422446 C/T cg21155796 chr2:242212141 HDLBP 0.87 6.47 0.5 2e-9 Prostate cancer; TGCT trans rs57221529 0.766 rs72703064 chr5:587825 T/C cg25482853 chr8:67687455 SGK3 1.2 10.12 0.67 6.42e-18 Lung disease severity in cystic fibrosis; TGCT cis rs8056742 0.730 rs34771435 chr16:85092201 T/A cg00229868 chr16:85520891 NA 0.36 4.83 0.4 3.96e-6 Amyotrophic lateral sclerosis; TGCT cis rs6695640 0.854 rs2762889 chr1:17733147 A/C cg25979543 chr1:17888104 ARHGEF10L -0.25 -4.48 -0.37 1.7e-5 Mean platelet volume; TGCT cis rs769267 1.000 rs2074090 chr19:19449686 G/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs1059312 0.808 rs12816551 chr12:129295616 T/C cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs9814567 0.712 rs9838621 chr3:134332319 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9916302 0.904 rs57399933 chr17:37551189 A/G cg15445000 chr17:37608096 MED1 -0.34 -4.79 -0.39 4.71e-6 Glomerular filtration rate (creatinine); TGCT cis rs67311347 1.000 rs28491638 chr3:40496263 T/C cg13683864 chr3:40499215 RPL14 -1.2 -13.25 -0.77 1.68e-25 Renal cell carcinoma; TGCT cis rs346785 0.640 rs9905488 chr17:74283535 A/G cg09812376 chr17:74270190 QRICH2 0.36 5.37 0.43 3.68e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs1800469 1.000 rs2241715 chr19:41856886 A/C cg09537434 chr19:41945824 ATP5SL -0.5 -4.66 -0.39 8.16e-6 Colorectal cancer; TGCT cis rs2456568 0.867 rs2462744 chr11:93682913 G/A cg17595323 chr11:93583763 C11orf90 -0.46 -6.01 -0.47 1.92e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6669384 0.774 rs61821315 chr1:208027696 C/T cg22525895 chr1:207977042 MIR29B2 -0.4 -5.69 -0.45 8.83e-8 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg06481639 chr22:41940642 POLR3H -0.73 -6.47 -0.5 2.07e-9 Vitiligo; TGCT cis rs1552244 0.688 rs7645137 chr3:10020549 A/AT cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 5.93 0.47 2.76e-8 Alzheimer's disease; TGCT cis rs1153858 1.000 rs4774579 chr15:45651803 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs523522 0.962 rs7471 chr12:120941215 T/C cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs8013055 0.796 rs28733392 chr14:105993258 G/A cg19700328 chr14:106028568 NA -0.48 -4.93 -0.4 2.62e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT trans rs941408 0.890 rs1640269 chr19:2793194 A/C cg19676328 chr12:49525230 TUBA1B -0.73 -6.74 -0.52 5.45e-10 Total cholesterol levels; TGCT cis rs644799 1.000 rs623191 chr11:95548359 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7208859 0.623 rs9915566 chr17:29132158 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6964587 1.000 rs2961020 chr7:91573308 G/A cg17063962 chr7:91808500 NA -0.91 -9.88 -0.66 2.45e-17 Breast cancer; TGCT cis rs4253772 0.550 rs55926596 chr22:46682955 C/T cg24881330 chr22:46731750 TRMU 1.01 4.95 0.41 2.35e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs9527 0.590 rs10883820 chr10:104764661 A/C cg04362960 chr10:104952993 NT5C2 -0.65 -5.54 -0.45 1.73e-7 Arsenic metabolism; TGCT cis rs9929218 0.679 rs9924886 chr16:68743939 A/C cg01251360 chr16:68772225 CDH1 0.29 4.64 0.38 8.58e-6 Colorectal cancer; TGCT trans rs7726839 0.540 rs72703095 chr5:601789 T/C cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs2463822 1.000 rs72921498 chr11:62113090 C/T cg23876832 chr11:62092739 NA -0.64 -4.72 -0.39 6.28e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs372883 0.638 rs117213 chr21:30720536 G/A cg24692254 chr21:30365293 RNF160 -0.54 -4.84 -0.4 3.83e-6 Pancreatic cancer; TGCT cis rs2153535 0.580 rs6921036 chr6:8455400 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT trans rs877282 1.000 rs10904552 chr10:774326 A/G cg22713356 chr15:30763199 NA 1.13 10.07 0.67 8.48e-18 Uric acid levels; TGCT cis rs3749237 1.000 rs11717256 chr3:49868520 C/T cg10152585 chr3:50297680 NA 0.51 4.84 0.4 3.79e-6 Resting heart rate; TGCT cis rs7043114 0.525 rs1053446 chr9:95146761 T/A cg14631576 chr9:95140430 CENPP -0.27 -4.56 -0.38 1.22e-5 Height; TGCT cis rs4862307 0.688 rs6552743 chr4:184990516 C/G cg06737308 chr4:185021514 ENPP6 0.37 5.41 0.44 3.19e-7 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs6460942 0.915 rs80345607 chr7:12442249 T/C cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT trans rs2622849 1.000 rs1676488 chr1:103390327 C/G cg25934198 chr9:139920781 C9orf139;ABCA2 0.49 6.91 0.53 2.27e-10 Bone mineral density change response to combined chemotherapy in acute lymphoblastic leukemia; TGCT cis rs7829975 0.510 rs332037 chr8:8722675 C/T cg17143192 chr8:8559678 CLDN23 0.46 4.7 0.39 6.77e-6 Mood instability; TGCT cis rs10751667 0.666 rs10794354 chr11:954615 A/T cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs66573146 0.901 rs55882710 chr4:7030704 G/A cg05069807 chr4:6945702 TBC1D14 0.34 4.84 0.4 3.83e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9633740 1.000 rs10748526 chr10:82273079 T/C cg01528321 chr10:82214614 TSPAN14 1.0 7.95 0.58 1.01e-12 Post bronchodilator FEV1; TGCT cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs986417 0.748 rs10142401 chr14:61039403 A/G cg18240143 chr14:60952599 C14orf39 0.82 4.51 0.38 1.46e-5 Gut microbiota (bacterial taxa); TGCT cis rs9393692 0.905 rs9366649 chr6:26329103 A/T cg00631329 chr6:26305371 NA 0.41 6.12 0.48 1.12e-8 Educational attainment; TGCT cis rs6540559 0.673 rs58637469 chr1:209971480 T/A cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs3848445 1.000 rs7214411 chr17:14288990 C/T cg01636575 chr17:13447853 HS3ST3A1 -0.97 -5.56 -0.45 1.59e-7 Protein quantitative trait loci; TGCT cis rs7659604 0.643 rs6838881 chr4:122663616 A/T cg06713675 chr4:122721982 EXOSC9 -0.45 -5.24 -0.43 6.75e-7 Type 2 diabetes; TGCT cis rs4742903 0.967 rs10820605 chr9:106881402 C/T cg21169611 chr9:106856078 SMC2 0.52 4.89 0.4 3.08e-6 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs7089973 0.872 rs34683721 chr10:116619849 G/A cg03647239 chr10:116582469 FAM160B1 0.52 4.64 0.38 8.75e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg05368731 chr17:41323189 NBR1 1.1 11.12 0.71 2.38e-20 Menopause (age at onset); TGCT cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.43 -4.56 -0.38 1.22e-5 Blood metabolite levels; TGCT cis rs9303401 1.000 rs9904677 chr17:56873025 A/G cg12560992 chr17:57184187 TRIM37 0.53 5.44 0.44 2.71e-7 Cognitive test performance; TGCT cis rs2404602 0.536 rs7165025 chr15:76766434 G/A cg22467129 chr15:76604101 ETFA -0.48 -5.9 -0.47 3.27e-8 Blood metabolite levels; TGCT cis rs2455799 0.559 rs7614145 chr3:15917898 A/G cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs9611519 0.929 rs12484971 chr22:41439304 A/T cg03806693 chr22:41940476 POLR3H -0.68 -6.1 -0.48 1.25e-8 Neuroticism; TGCT cis rs950776 0.518 rs1504545 chr15:78818471 C/G cg06917634 chr15:78832804 PSMA4 -0.94 -9.29 -0.64 6.76e-16 Sudden cardiac arrest; TGCT cis rs11098499 0.863 rs1480939 chr4:120456927 T/C cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs447921 0.861 rs56154175 chr17:74419086 C/T cg09812376 chr17:74270190 QRICH2 -0.45 -4.48 -0.37 1.69e-5 Mitochondrial DNA levels; TGCT cis rs2153535 0.580 rs4960412 chr6:8438261 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs4824093 0.610 rs3761496 chr22:50246466 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -6.76 -0.52 4.86e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs17152411 1.000 rs733401 chr10:126594158 A/T cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs116095464 0.558 rs2162870 chr5:228129 G/A cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs1577917 0.917 rs2084293 chr6:86566002 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs1997103 1.000 rs4947501 chr7:55407342 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs71597109 0.639 rs4699262 chr4:102726005 A/G cg14855874 chr4:102712397 BANK1 -0.42 -4.82 -0.4 4.12e-6 Chronic lymphocytic leukemia; TGCT cis rs9916302 0.851 rs12936646 chr17:37647450 A/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs73110464 0.609 rs727266 chr12:53356411 C/T cg14581129 chr12:53358946 NA -0.63 -6.78 -0.52 4.39e-10 Cancer (pleiotropy); TGCT cis rs3540 0.597 rs4932346 chr15:91048991 T/C cg22089800 chr15:90895588 ZNF774 -0.76 -7.77 -0.57 2.55e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7666738 0.830 rs13125537 chr4:98978428 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4566357 1.000 rs7567796 chr2:227922109 T/A cg11843606 chr2:227700838 RHBDD1 -0.57 -5.17 -0.42 8.99e-7 Coronary artery disease; TGCT cis rs4638749 1.000 rs1466212 chr2:108856532 G/A cg06795125 chr2:108905320 SULT1C2 -0.39 -4.81 -0.4 4.26e-6 Blood pressure; TGCT cis rs9296661 0.522 rs4510663 chr6:51661714 G/A cg20180370 chr6:50691003 TFAP2D -0.48 -4.67 -0.39 7.68e-6 Weight loss (gastric bypass surgery); TGCT cis rs7666738 0.830 rs4699603 chr4:99056172 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs929354 0.709 rs1182363 chr7:157019151 A/G cg05182265 chr7:156933206 UBE3C 0.4 9.08 0.63 2.11e-15 Body mass index; TGCT cis rs3020736 0.500 rs6002614 chr22:42501802 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs17711722 0.740 rs7809991 chr7:65406218 A/G cg18876405 chr7:65276391 NA 0.37 5.89 0.47 3.33e-8 Calcium levels; TGCT cis rs7819412 0.806 rs10113808 chr8:10926892 C/A cg27411982 chr8:10470053 RP1L1 -0.21 -4.61 -0.38 9.95e-6 Triglycerides; TGCT cis rs2970818 0.831 rs2909381 chr12:4606527 T/C cg02722637 chr12:4922070 KCNA6 0.3 4.49 0.37 1.59e-5 Phosphorus levels; TGCT cis rs4478858 0.684 rs16865957 chr1:31753353 G/A cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.27 4.78 0.39 4.88e-6 Schizophrenia; TGCT cis rs4803468 1.000 rs4674 chr19:41930396 A/G cg09537434 chr19:41945824 ATP5SL -0.91 -10.63 -0.69 3.74e-19 Height; TGCT cis rs9467773 1.000 rs9461271 chr6:26554968 G/A cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs6500602 0.727 rs11644481 chr16:4581002 T/G cg08645402 chr16:4508243 NA 0.19 5.32 0.43 4.65e-7 Schizophrenia; TGCT cis rs7945705 0.818 rs2653613 chr11:8879105 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -4.64 -0.38 8.82e-6 Hemoglobin concentration; TGCT cis rs9906944 0.933 rs12945020 chr17:47082775 G/A cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.8 -0.4 4.47e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs4631830 0.863 rs4554834 chr10:51530146 A/C cg10326726 chr10:51549505 MSMB -0.26 -5.3 -0.43 5.17e-7 Prostate-specific antigen levels; TGCT cis rs7639513 0.767 rs7617041 chr3:12709167 A/G cg23032965 chr3:12705835 RAF1 0.77 8.55 0.61 3.81e-14 Itch intensity from mosquito bite; TGCT cis rs427394 0.659 rs274725 chr5:6717408 C/G cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs6570726 0.764 rs1912023 chr6:145824278 C/A cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg17054783 chr10:134559939 INPP5A 0.23 4.64 0.38 8.89e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2303745 0.640 rs10403581 chr19:17384192 A/C cg04248312 chr19:17393744 ANKLE1 -0.34 -5.71 -0.46 7.88e-8 Systemic lupus erythematosus; TGCT cis rs9788682 1.000 rs12441426 chr15:78812329 T/C cg24631222 chr15:78858424 CHRNA5 0.89 7.75 0.57 2.91e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs5771242 0.518 rs67881086 chr22:50673439 G/A cg16473166 chr22:50639996 SELO 0.58 4.77 0.39 5.03e-6 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs6121246 0.529 rs6060359 chr20:30209740 A/G cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs7940866 0.834 rs10894302 chr11:130861994 C/T cg12179176 chr11:130786555 SNX19 0.62 5.77 0.46 5.87e-8 Schizophrenia; TGCT cis rs4601821 0.823 rs4938013 chr11:113264470 A/C cg14159747 chr11:113255604 NA 0.38 4.49 0.37 1.61e-5 Alcoholic chronic pancreatitis; TGCT cis rs12220238 0.722 rs6480744 chr10:76398989 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.59 4.54 0.38 1.29e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9430161 0.579 rs79323519 chr1:11036050 T/C cg27631724 chr1:11040367 C1orf127 0.55 6.05 0.48 1.55e-8 Ewing sarcoma; TGCT cis rs11690462 0.926 rs12467721 chr2:26558489 T/G cg04726446 chr2:26624865 C2orf39 0.44 4.68 0.39 7.29e-6 Coronary artery disease; TGCT cis rs918629 0.679 rs56002885 chr5:95269602 A/G cg16656078 chr5:95278638 ELL2 -0.28 -4.55 -0.38 1.25e-5 IgG glycosylation; TGCT cis rs17345786 0.861 rs17402964 chr3:101067945 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.85 8.98 0.63 3.67e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs7100689 0.784 rs2153455 chr10:82139732 T/C cg01528321 chr10:82214614 TSPAN14 0.89 8.97 0.63 3.94e-15 Post bronchodilator FEV1; TGCT cis rs2180341 0.920 rs6906717 chr6:127596782 C/A cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs66573146 1.000 rs55913461 chr4:7017509 C/T cg01220768 chr4:7056774 TADA2B 0.41 5.11 0.42 1.2e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs10986311 0.775 rs6478658 chr9:127127810 A/G cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.78 -0.39 4.84e-6 Vitiligo; TGCT cis rs6500602 0.673 rs4786513 chr16:4576423 T/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 5.16 0.42 9.66e-7 Schizophrenia; TGCT cis rs6424115 0.830 rs2501431 chr1:24201643 G/A cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs7226408 0.857 rs72887066 chr18:34496371 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1218582 0.628 rs12130132 chr1:154880386 C/T cg06221963 chr1:154839813 KCNN3 -0.69 -11.52 -0.72 2.49e-21 Prostate cancer; TGCT cis rs7399018 0.739 rs10747608 chr12:51616582 A/G cg25754956 chr12:51612065 POU6F1 0.74 6.95 0.53 1.84e-10 Cisplatin-induced ototoxicity; TGCT cis rs28595532 0.920 rs17325017 chr4:119774607 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs7760949 0.852 rs9349847 chr6:13927711 T/C cg27413430 chr6:13925136 RNF182 0.73 6.83 0.52 3.37e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7826238 0.601 rs2976907 chr8:8345168 C/T cg15556689 chr8:8085844 FLJ10661 0.6 5.55 0.45 1.62e-7 Systolic blood pressure; TGCT cis rs12368653 0.840 rs10877020 chr12:58188014 G/A cg12615879 chr12:58013172 SLC26A10 0.5 5.99 0.47 2.16e-8 Multiple sclerosis; TGCT cis rs4906332 1.000 rs28711288 chr14:103906126 T/C cg26031613 chr14:104095156 KLC1 -0.55 -4.9 -0.4 2.88e-6 Coronary artery disease; TGCT cis rs7940866 0.834 rs10791105 chr11:130839161 A/G cg05962950 chr11:130786565 SNX19 0.73 7.14 0.54 6.88e-11 Schizophrenia; TGCT cis rs36051895 0.659 rs10974938 chr9:5056037 A/G cg02405213 chr9:5042618 JAK2 -0.75 -9.15 -0.63 1.42e-15 Pediatric autoimmune diseases; TGCT cis rs3096299 0.967 rs2965935 chr16:89481274 C/T cg06640241 chr16:89574553 SPG7 -0.62 -6.05 -0.48 1.56e-8 Multiple myeloma (IgH translocation); TGCT cis rs909674 0.734 rs5757675 chr22:39838892 G/T cg11247378 chr22:39784982 NA -0.73 -8.98 -0.63 3.69e-15 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs3845702 1.000 rs3845697 chr2:180798553 C/T cg01881094 chr2:180872142 CWC22 0.66 5.81 0.46 4.86e-8 Schizophrenia; TGCT cis rs858239 0.508 rs2390754 chr7:23190494 A/G cg05602783 chr7:23145260 KLHL7 -0.69 -5.57 -0.45 1.54e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs8067545 0.750 rs4925077 chr17:19982276 C/T cg13482628 chr17:19912719 NA 0.51 4.59 0.38 1.09e-5 Schizophrenia; TGCT cis rs611744 0.647 rs1457211 chr8:109261318 C/T cg21045802 chr8:109455806 TTC35 -0.72 -7.28 -0.55 3.42e-11 Dupuytren's disease; TGCT cis rs4319547 0.774 rs7295105 chr12:123124225 G/A cg23029597 chr12:123009494 RSRC2 -0.27 -4.73 -0.39 6.11e-6 Body mass index; TGCT cis rs9682041 0.696 rs13101192 chr3:170080752 C/G cg11886554 chr3:170076028 SKIL 0.6 4.74 0.39 5.77e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg10802521 chr3:52805072 NEK4 -0.65 -7.6 -0.56 6.21e-12 Bipolar disorder; TGCT cis rs6121246 0.559 rs6060962 chr20:30397847 A/G cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs1580019 0.520 rs6945238 chr7:32646096 C/T cg06627557 chr7:32535165 LSM5;AVL9 -0.94 -8.9 -0.62 5.7e-15 Cognitive ability; TGCT cis rs2288884 1.000 rs12609219 chr19:52580996 T/C cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs10504229 0.636 rs72649123 chr8:58045789 A/T cg08280861 chr8:58055591 NA 0.4 5.57 0.45 1.49e-7 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.808 rs17031005 chr2:43761299 A/G cg03762820 chr2:43823654 THADA -0.54 -4.95 -0.41 2.37e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7822232 0.908 rs6558295 chr8:145139522 C/G cg06239191 chr8:145163136 KIAA1875 -0.88 -6.45 -0.5 2.26e-9 Blood metabolite levels; TGCT cis rs2832191 0.716 rs9983051 chr21:30371890 C/T cg24692254 chr21:30365293 RNF160 0.97 11.35 0.71 6.68e-21 Dental caries; TGCT cis rs35306767 0.904 rs35667562 chr10:950630 G/A cg20503657 chr10:835505 NA 0.81 12.21 0.74 5.29e-23 Eosinophil percentage of granulocytes; TGCT cis rs7020830 0.861 rs13289001 chr9:37311592 A/G cg14235030 chr9:37121269 ZCCHC7 0.41 4.49 0.37 1.58e-5 Schizophrenia; TGCT cis rs6964587 1.000 rs13231238 chr7:91653851 T/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs3809566 1.000 rs4775612 chr15:63332157 T/C cg05507819 chr15:63340323 TPM1 0.48 4.52 0.38 1.4e-5 Platelet count; TGCT cis rs4851254 0.618 rs7596359 chr2:100665274 T/G cg07810366 chr2:100720526 AFF3 -0.49 -5.09 -0.42 1.28e-6 Intelligence (multi-trait analysis); TGCT cis rs2797160 1.000 rs2797160 chr6:126010116 A/G cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs1552244 0.572 rs67439440 chr3:10169503 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs2963155 0.518 rs853178 chr5:142634799 C/T cg17617527 chr5:142782415 NR3C1 0.85 6.28 0.49 5.22e-9 Breast cancer; TGCT cis rs4906332 0.966 rs7159665 chr14:103984616 C/T cg26031613 chr14:104095156 KLC1 -0.56 -5.04 -0.41 1.64e-6 Coronary artery disease; TGCT cis rs2153535 0.601 rs9379224 chr6:8538413 A/G cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2153535 0.580 rs9406167 chr6:8502852 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2227564 0.533 rs3870402 chr10:75473787 A/C cg04320760 chr10:75533139 FUT11 -0.32 -4.5 -0.37 1.56e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 7.21 0.54 4.84e-11 Schizophrenia; TGCT cis rs7264396 0.635 rs6058375 chr20:34531997 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs8013055 0.846 rs12717698 chr14:105979015 G/A cg23356831 chr14:105996513 TMEM121 0.37 5.32 0.43 4.61e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs3784262 1.000 rs1372368 chr15:58297363 C/T cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.82 -0.57 1.98e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs992157 0.798 rs10193383 chr2:219157692 C/T cg00012203 chr2:219082015 ARPC2 0.81 8.08 0.59 4.97e-13 Colorectal cancer; TGCT cis rs9611565 0.649 rs5758442 chr22:42133060 T/C cg06634786 chr22:41940651 POLR3H 0.79 7.29 0.55 3.13e-11 Vitiligo; TGCT cis rs899997 1.000 rs4887078 chr15:79011073 C/T cg04896959 chr15:78267971 NA 0.35 5.55 0.45 1.65e-7 Coronary artery disease or large artery stroke; TGCT cis rs155076 1.000 rs2783107 chr13:21837532 C/A cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs6088590 0.561 rs11167239 chr20:33140472 G/A cg08999081 chr20:33150536 PIGU 0.28 5.41 0.44 3.11e-7 Coronary artery disease; TGCT cis rs71597109 0.607 rs35446399 chr4:102729766 G/A cg14855874 chr4:102712397 BANK1 0.42 4.59 0.38 1.09e-5 Chronic lymphocytic leukemia; TGCT cis rs227163 0.905 rs227162 chr1:7960565 G/T cg23631229 chr1:7962850 NA -0.33 -4.55 -0.38 1.28e-5 Rheumatoid arthritis; TGCT cis rs360798 0.512 rs11893131 chr2:63079528 C/A cg17519650 chr2:63277830 OTX1 0.65 6.0 0.47 2.03e-8 Coronary artery disease; TGCT cis rs10504229 1.000 rs66479724 chr8:58188309 T/G cg22535103 chr8:58192502 C8orf71 -0.42 -5.39 -0.44 3.49e-7 Developmental language disorder (linguistic errors); TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg21237687 chr17:6899380 ALOX12 0.52 5.6 0.45 1.33e-7 Tonsillectomy; TGCT cis rs4975709 0.589 rs1466606 chr5:1865055 C/T cg12288994 chr5:1860383 NA 0.25 4.99 0.41 2.02e-6 Cardiovascular disease risk factors; TGCT cis rs7703051 0.585 rs918623 chr5:74596682 A/C cg19683494 chr5:74908142 NA 0.68 6.65 0.51 8.36e-10 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs651907 0.557 rs11914318 chr3:101453858 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.21 0.68 3.89e-18 Colorectal cancer; TGCT cis rs7044106 0.791 rs3904196 chr9:123480369 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 6.99 0.53 1.48e-10 Hip circumference adjusted for BMI; TGCT cis rs763121 0.853 rs5750626 chr22:38977890 G/C cg06022373 chr22:39101656 GTPBP1 0.8 7.88 0.58 1.42e-12 Menopause (age at onset); TGCT cis rs7949030 0.523 rs12223627 chr11:62368557 G/C cg11742103 chr11:62369870 EML3;MTA2 0.55 6.35 0.5 3.71e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10197940 0.578 rs2045025 chr2:152317531 T/C cg06191203 chr2:152266755 RIF1 -0.58 -4.88 -0.4 3.22e-6 Lung cancer; TGCT cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg18765753 chr7:1198926 ZFAND2A -0.51 -6.04 -0.48 1.7e-8 Longevity;Endometriosis; TGCT cis rs910316 1.000 rs12589815 chr14:75544101 C/T cg11812906 chr14:75593930 NEK9 0.74 7.18 0.54 5.58e-11 Height; TGCT trans rs1864729 1.000 rs2853320 chr8:98283523 C/G cg08679828 chr8:102218111 ZNF706 -1.08 -7.52 -0.56 9.47e-12 Estradiol plasma levels (breast cancer); TGCT cis rs3820068 0.705 rs72645804 chr1:15868387 A/C cg05660106 chr1:15850417 CASP9 1.15 13.74 0.78 1.14e-26 Systolic blood pressure; TGCT cis rs61990749 0.544 rs3759728 chr14:78230159 A/T cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs5769707 0.521 rs5769720 chr22:50062133 G/C cg05373962 chr22:49881684 NA -0.32 -5.47 -0.44 2.43e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9467773 1.000 rs767471 chr6:26557854 C/T cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs3820928 0.775 rs10179756 chr2:227897076 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT trans rs11722228 0.508 rs73212864 chr4:10104191 G/A cg26043149 chr18:55253948 FECH 1.18 11.39 0.72 5.19e-21 Gout;Urate levels;Serum uric acid levels; TGCT cis rs4665809 1.000 rs4665811 chr2:26260017 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.22 -0.49 7.14e-9 Gut microbiome composition (summer); TGCT cis rs9467711 1.000 rs9467704 chr6:26319486 A/G cg26531700 chr6:26746687 NA 1.04 5.71 0.46 7.81e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg06634786 chr22:41940651 POLR3H -0.9 -8.93 -0.63 4.7e-15 Vitiligo; TGCT cis rs9527 0.590 rs6584537 chr10:104778267 C/G cg15744005 chr10:104629667 AS3MT -0.42 -4.92 -0.4 2.74e-6 Arsenic metabolism; TGCT cis rs7666738 0.785 rs11944120 chr4:99079932 A/C cg17366294 chr4:99064904 C4orf37 0.71 5.48 0.44 2.27e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.863 rs28718422 chr4:120466304 C/A cg09307838 chr4:120376055 NA 0.72 6.87 0.52 2.81e-10 Corneal astigmatism; TGCT cis rs6906287 0.561 rs2078079 chr6:118705213 G/A cg21191810 chr6:118973309 C6orf204 0.27 4.55 0.38 1.28e-5 Electrocardiographic conduction measures; TGCT cis rs9818758 0.607 rs34823813 chr3:49749976 G/A cg00383909 chr3:49044727 WDR6 1.31 6.62 0.51 9.53e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs13256369 1.000 rs13256369 chr8:8577379 T/C cg18904891 chr8:8559673 CLDN23 0.64 5.87 0.47 3.71e-8 Obesity-related traits; TGCT cis rs7666738 0.830 rs62318503 chr4:98935479 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 0.767 rs11190519 chr10:102175133 C/T cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10992471 0.575 rs1152759 chr9:95129359 T/C cg13798575 chr9:95087839 CENPP;NOL8 0.62 5.98 0.47 2.2e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs916888 0.821 rs199513 chr17:44856932 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 0.52 4.72 0.39 6.16e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4819052 0.765 rs2838852 chr21:46677037 C/A cg06618935 chr21:46677482 NA -0.36 -5.43 -0.44 2.87e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9818758 0.607 rs35673421 chr3:49139406 G/A cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2820315 1.000 rs1400875 chr1:201821443 T/C cg12730843 chr1:201915899 LMOD1 -0.27 -4.76 -0.39 5.2e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Vitiligo; TGCT cis rs8070740 0.898 rs8074617 chr17:5323989 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.77 0.39 5.1e-6 Menopause (age at onset); TGCT cis rs7246657 0.654 rs10407568 chr19:38123009 A/T cg03611452 chr19:38183253 ZNF781 0.59 4.76 0.39 5.34e-6 Coronary artery calcification; TGCT cis rs698813 0.604 rs1596010 chr2:44491804 A/C cg00619915 chr2:44497795 NA -0.24 -5.5 -0.44 2.05e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs858239 0.600 rs6961406 chr7:23134891 C/T cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs10788264 0.621 rs7907952 chr10:124056774 C/T cg05723130 chr10:124248994 HTRA1 -0.2 -4.58 -0.38 1.12e-5 Total body bone mineral density; TGCT cis rs6952407 1 rs6952407 chr7:66045512 A/G cg00343986 chr7:65444356 GUSB -0.24 -5.29 -0.43 5.4e-7 Cotinine glucuronidation; TGCT cis rs7586879 0.681 rs6545800 chr2:25118885 A/G cg15423357 chr2:25149977 NA -0.5 -4.89 -0.4 3.06e-6 Body mass index; TGCT trans rs4824093 0.545 rs58876234 chr22:50258868 G/A cg09872104 chr7:134855509 C7orf49 -0.94 -7.68 -0.57 4.2e-12 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2479724 0.840 rs10498752 chr6:41768510 T/C cg08135965 chr6:41755394 TOMM6 -0.45 -4.53 -0.38 1.38e-5 Menarche (age at onset); TGCT cis rs240764 0.853 rs2398132 chr6:100981200 A/C cg21058520 chr6:100914733 NA 0.37 4.86 0.4 3.54e-6 Neuroticism; TGCT cis rs1385374 0.858 rs12298615 chr12:129286756 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.69 -0.39 6.99e-6 Systemic lupus erythematosus; TGCT cis rs1163251 0.902 rs639216 chr1:120217414 C/T cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs6598955 0.543 rs3795689 chr1:26560366 C/G cg24519413 chr1:26490540 NA -0.26 -4.73 -0.39 6.1e-6 Obesity-related traits; TGCT trans rs66573146 0.831 rs67702333 chr4:6983040 C/G cg07817883 chr1:32538562 TMEM39B 1.42 7.53 0.56 8.92e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs4911259 0.552 rs13038017 chr20:31467551 T/C cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs6558530 0.666 rs6558526 chr8:1702572 A/G cg09410841 chr8:1729607 CLN8 0.72 6.49 0.5 1.87e-9 Systolic blood pressure; TGCT cis rs7647973 0.626 rs9830730 chr3:49675875 G/C cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs514406 0.763 rs9988539 chr1:53213884 T/C cg08859206 chr1:53392774 SCP2 0.4 5.88 0.47 3.56e-8 Monocyte count; TGCT cis rs7829975 0.511 rs2976902 chr8:8341105 T/G cg08975724 chr8:8085496 FLJ10661 0.55 5.37 0.43 3.82e-7 Mood instability; TGCT cis rs2806561 0.577 rs488438 chr1:23498999 T/A cg12483005 chr1:23474871 LUZP1 0.39 4.88 0.4 3.24e-6 Height; TGCT cis rs2729354 0.953 rs1846567 chr11:57357593 T/C cg24343310 chr11:57249947 NA 0.29 4.71 0.39 6.6e-6 Blood protein levels; TGCT cis rs13256369 0.851 rs13249700 chr8:8563637 C/T cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs2075165 1.000 rs2075165 chr1:156215899 G/A cg20302342 chr1:156215951 PAQR6 0.36 5.24 0.43 6.62e-7 Tonsillectomy; TGCT cis rs12477438 0.520 rs11695379 chr2:99742161 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.85 8.48 0.61 5.52e-14 Chronic sinus infection; TGCT trans rs629535 0.699 rs539956 chr8:70033647 G/A cg21567404 chr3:27674614 NA 0.57 9.15 0.63 1.45e-15 Dupuytren's disease; TGCT cis rs10782582 0.593 rs12130832 chr1:76234294 T/C cg10523679 chr1:76189770 ACADM -0.61 -6.17 -0.48 8.87e-9 Daytime sleep phenotypes; TGCT cis rs981844 1.000 rs2118862 chr4:154657782 A/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs1865760 0.566 rs2858993 chr6:26087856 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.8 7.46 0.56 1.3e-11 Height; TGCT cis rs1466788 1.000 rs7533623 chr1:110616475 T/C cg11787288 chr1:111506544 C1orf103 0.49 4.44 0.37 1.93e-5 Blood metabolite levels; TGCT cis rs10114408 0.959 rs10992957 chr9:96651655 G/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs28595532 0.920 rs56283736 chr4:119747268 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs394563 0.619 rs4895787 chr6:149646500 G/A cg03678062 chr6:149772716 ZC3H12D 0.37 4.75 0.39 5.59e-6 Dupuytren's disease; TGCT cis rs2730260 0.537 rs55683317 chr7:158878599 C/T cg27122614 chr7:157913741 PTPRN2 0.42 4.48 0.37 1.68e-5 Myopia (pathological); TGCT cis rs3935685 0.874 rs4578613 chr15:78002360 A/T cg25212270 chr15:78015279 NA 0.27 5.66 0.45 9.87e-8 Intelligence (multi-trait analysis); TGCT cis rs4253772 0.530 rs11090865 chr22:46731689 G/T cg24881330 chr22:46731750 TRMU 0.97 4.75 0.39 5.52e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg22663859 chr13:21900854 NA 0.34 4.93 0.4 2.59e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9527 0.590 rs943039 chr10:104825132 C/T cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT cis rs2204008 0.837 rs34381557 chr12:38181983 T/C cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT cis rs2228479 0.619 rs77847775 chr16:89896243 C/T cg06558623 chr16:89946397 TCF25 0.55 4.77 0.39 5.13e-6 Skin colour saturation; TGCT cis rs11690935 0.921 rs908670 chr2:172690180 T/C cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.01 -0.73 1.6400000000000001e-22 Schizophrenia; TGCT cis rs2980439 0.557 rs2921056 chr8:8319182 T/C cg15556689 chr8:8085844 FLJ10661 0.7 6.4 0.5 2.85e-9 Neuroticism; TGCT cis rs1971762 0.545 rs10747675 chr12:54000031 A/G cg16917193 chr12:54089295 NA -0.92 -9.72 -0.66 5.94e-17 Height; TGCT cis rs1008375 0.932 rs7677212 chr4:17675932 A/G cg10189774 chr4:17578691 LAP3 -0.55 -4.75 -0.39 5.62e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9467773 1.000 rs1884948 chr6:26567988 G/A cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs4665630 0.522 rs114880940 chr2:23930352 G/A cg08063864 chr2:24346004 PFN4;LOC375190 1.13 4.97 0.41 2.21e-6 Hypertension; TGCT trans rs1814175 0.817 rs7946556 chr11:49944874 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT trans rs4957048 0.577 rs56294732 chr5:568144 T/C cg11887960 chr12:57824829 NA 1.02 7.74 0.57 3.07e-12 Ulcerative colitis; TGCT cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg11062466 chr8:58055876 NA 0.42 4.51 0.38 1.48e-5 Developmental language disorder (linguistic errors); TGCT cis rs11170631 0.507 rs12307701 chr12:54090724 A/C cg16917193 chr12:54089295 NA 1.34 17.35 0.84 5.83e-35 Height; TGCT cis rs1218582 0.772 rs906593 chr1:154885255 G/A cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs4788570 0.566 rs2052873 chr16:71505303 C/T cg06353428 chr16:71660113 MARVELD3 -1.1 -6.61 -0.51 1.02e-9 Intelligence (multi-trait analysis); TGCT cis rs6964587 1.000 rs9785013 chr7:91674302 G/A cg17063962 chr7:91808500 NA 0.88 9.63 0.65 9.8e-17 Breast cancer; TGCT cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg09436375 chr6:42928200 GNMT -0.42 -5.44 -0.44 2.78e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6582630 0.555 rs7969922 chr12:38529491 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.9 0.4 2.91e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2180341 0.538 rs4392733 chr6:127712603 T/C cg27446573 chr6:127587934 RNF146 0.64 6.01 0.47 1.95e-8 Breast cancer; TGCT cis rs910316 0.967 rs11159116 chr14:75550584 G/T cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs782590 0.935 rs2627776 chr2:55873301 T/A cg18811423 chr2:55921094 PNPT1 0.66 6.83 0.52 3.46e-10 Metabolic syndrome; TGCT cis rs34783982 0.529 rs12917490 chr15:89473805 A/C cg26213453 chr15:89455860 MFGE8 -0.34 -4.77 -0.39 5e-6 Squamous cell lung carcinoma; TGCT cis rs9926296 0.605 rs7205053 chr16:89856763 G/C cg03388025 chr16:89894329 SPIRE2 0.5 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs4629710 0.592 rs9492877 chr6:131562577 C/G cg12606694 chr6:131520996 AKAP7 0.4 4.76 0.39 5.26e-6 Multiple myeloma (IgH translocation); TGCT cis rs5769765 0.818 rs8140681 chr22:50292081 C/A cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.91 0.47 3.12e-8 Schizophrenia; TGCT cis rs4936894 0.500 rs7107539 chr11:124180282 G/T cg27160556 chr11:124181099 OR8D1 0.39 4.81 0.4 4.32e-6 Aging (time to death); TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg06873352 chr17:61820015 STRADA 0.58 6.35 0.5 3.76e-9 Prudent dietary pattern; TGCT cis rs7615952 0.932 rs11922218 chr3:125631289 C/T cg05084668 chr3:125655381 ALG1L -0.74 -6.05 -0.48 1.6e-8 Blood pressure (smoking interaction); TGCT cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg03188948 chr7:1209495 NA 0.72 6.43 0.5 2.44e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7208859 0.673 rs9891413 chr17:29208209 G/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs614226 1.000 rs12310837 chr12:120880572 C/T cg01236616 chr12:121019343 POP5 1.2 12.21 0.74 5.39e-23 Type 1 diabetes nephropathy; TGCT cis rs10883723 0.810 rs10786671 chr10:104271303 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7666738 0.716 rs1426660 chr4:98876792 T/A cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12510870 0.599 rs7676850 chr4:74449693 C/T cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs7172809 0.615 rs74026926 chr15:77802961 T/C cg22256960 chr15:77711686 NA -0.52 -4.9 -0.4 2.91e-6 Glucose homeostasis traits; TGCT cis rs826838 1.000 rs860400 chr12:39081279 A/G cg26384229 chr12:38710491 ALG10B -0.85 -8.09 -0.59 4.68e-13 Heart rate; TGCT cis rs13064447 0.845 rs58411770 chr3:12773868 C/T cg20675869 chr3:12750130 NA -0.2 -5.14 -0.42 1.06e-6 Major depression and alcohol dependence; TGCT cis rs2404602 0.583 rs12907668 chr15:76589767 A/T cg26408565 chr15:76604113 ETFA -0.45 -6.36 -0.5 3.61e-9 Blood metabolite levels; TGCT cis rs875971 0.862 rs10256544 chr7:65675128 A/G cg11764359 chr7:65958608 NA 0.57 5.13 0.42 1.07e-6 Aortic root size; TGCT cis rs7267979 0.966 rs2261790 chr20:25262789 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2836974 0.666 rs12626405 chr21:40663121 G/T cg11890956 chr21:40555474 PSMG1 -0.76 -7.32 -0.55 2.7e-11 Cognitive function; TGCT cis rs748404 0.660 rs694725 chr15:43756210 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.71 0.39 6.65e-6 Lung cancer; TGCT cis rs7927592 0.513 rs608343 chr11:68196830 T/C cg16797656 chr11:68205561 LRP5 0.28 5.13 0.42 1.1e-6 Total body bone mineral density; TGCT cis rs972578 0.532 rs4822251 chr22:43415060 A/G cg03373887 chr22:44389424 SAMM50 0.2 4.51 0.38 1.48e-5 Mean platelet volume; TGCT cis rs2075165 0.838 rs12072638 chr1:156267480 T/G cg16558208 chr1:156270281 VHLL 0.27 4.83 0.4 3.87e-6 Tonsillectomy; TGCT cis rs4237845 0.735 rs11172375 chr12:58291574 G/C cg23860436 chr12:58378763 NA 0.35 4.92 0.4 2.7e-6 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.629 rs12991172 chr2:100941671 A/G cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs17767294 0.708 rs72847365 chr6:27837227 G/A cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs497273 0.511 rs1151862 chr12:121331285 G/A cg02419362 chr12:121203948 SPPL3 -0.19 -4.51 -0.38 1.48e-5 Systemic lupus erythematosus; TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs10096908 0.892 rs10086218 chr8:41641757 A/G cg13603914 chr8:41518004 ANK1;MIR486 0.39 4.53 0.38 1.38e-5 Hypertension;Blood pressure traits (multi-trait analysis);Systolic blood pressure; TGCT cis rs79349575 0.749 rs12601672 chr17:47006493 T/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg17971929 chr21:40555470 PSMG1 0.98 9.41 0.65 3.31e-16 Cognitive function; TGCT cis rs3858526 0.606 rs10838883 chr11:5952147 G/A cg25319279 chr11:5960081 NA 0.4 4.77 0.39 5.07e-6 DNA methylation (variation); TGCT cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg13866156 chr1:1669148 SLC35E2 -0.24 -5.87 -0.47 3.74e-8 Body mass index; TGCT cis rs314370 0.855 rs76181418 chr7:100494960 G/T cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs6901250 0.807 rs1606366 chr6:117132438 C/G cg12892004 chr6:117198278 RFX6 0.54 6.6 0.51 1.05e-9 C-reactive protein levels; TGCT cis rs2073300 1.000 rs6114139 chr20:23458390 T/G cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs2274273 0.682 rs7151224 chr14:55517262 G/A cg01923255 chr14:55878535 KIAA0831 0.58 4.91 0.4 2.78e-6 Protein biomarker; TGCT cis rs1577917 1.000 rs12204365 chr6:86700532 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs7547997 0.649 rs7543890 chr1:158342937 A/G cg03528325 chr1:158223921 CD1A 0.33 4.56 0.38 1.22e-5 QRS duration; TGCT cis rs9972944 0.902 rs59009755 chr17:63772263 C/T cg07283582 chr17:63770753 CCDC46 0.27 5.27 0.43 5.91e-7 Total body bone mineral density; TGCT cis rs832540 0.512 rs33320 chr5:56206529 C/T cg12311346 chr5:56204834 C5orf35 -0.49 -4.91 -0.4 2.78e-6 Coronary artery disease; TGCT cis rs7249142 0.549 rs72997174 chr19:19294389 T/C cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.51 4.9 0.4 2.98e-6 IgG glycosylation; TGCT cis rs9549367 0.713 rs2476328 chr13:113829350 C/T cg18105134 chr13:113819100 PROZ 0.46 8.12 0.59 3.94e-13 Platelet distribution width; TGCT trans rs459571 0.959 rs408307 chr9:136892523 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 0.7 7.46 0.56 1.29e-11 Platelet distribution width; TGCT cis rs12950390 0.893 rs11079789 chr17:45849715 A/G cg06532163 chr17:45867833 NA 0.34 5.31 0.43 4.82e-7 IgG glycosylation; TGCT cis rs2486288 0.656 rs1706768 chr15:45569443 T/C cg26924012 chr15:45694286 SPATA5L1 -0.82 -8.18 -0.59 2.85e-13 Glomerular filtration rate; TGCT cis rs10510102 0.810 rs12267347 chr10:123698625 A/T cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs514406 0.825 rs6695819 chr1:53223366 T/C cg01802117 chr1:53393560 SCP2 0.43 5.13 0.42 1.1e-6 Monocyte count; TGCT cis rs9858542 0.537 rs56038006 chr3:49362369 C/T cg08550065 chr3:50336684 HYAL3;NAT6 0.65 4.53 0.38 1.37e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT trans rs877282 0.891 rs11253393 chr10:788824 G/T cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs8017423 0.608 rs12589866 chr14:90820977 T/C cg04374321 chr14:90722782 PSMC1 -0.56 -5.62 -0.45 1.19e-7 Mortality in heart failure; TGCT cis rs704 0.628 rs1128161 chr17:26721895 G/A cg10342447 chr17:26645325 TMEM97 -0.47 -4.69 -0.39 7.21e-6 Osteoprotegerin levels; TGCT cis rs9894429 0.646 rs58398000 chr17:79576923 G/A cg18240062 chr17:79603768 NPLOC4 -0.56 -4.92 -0.4 2.67e-6 Eye color traits; TGCT cis rs10514758 0.744 rs1521566 chr3:114808210 C/T cg05943254 chr3:114009756 NA 0.76 4.53 0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs12413816 0.963 rs10796116 chr10:13762786 C/T cg16485048 chr10:13749193 FRMD4A -0.26 -5.35 -0.43 4.08e-7 Red cell distribution width; TGCT cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg03452623 chr4:187889614 NA -0.36 -5.3 -0.43 5.01e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4786125 0.587 rs9938245 chr16:6926744 T/G cg03623568 chr16:6915990 A2BP1 -0.42 -6.23 -0.49 6.77e-9 Heart rate variability traits (SDNN); TGCT cis rs9329221 0.935 rs3750311 chr8:10283602 C/A cg12940923 chr8:10282607 MSRA -0.2 -4.79 -0.39 4.75e-6 Neuroticism; TGCT cis rs3806843 0.576 rs246005 chr5:140339884 A/C cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7615952 1.000 rs9289275 chr3:125648659 A/T cg05084668 chr3:125655381 ALG1L -0.76 -6.36 -0.5 3.5e-9 Blood pressure (smoking interaction); TGCT cis rs6952808 0.578 rs6949478 chr7:1841342 A/G cg21782813 chr7:2030301 MAD1L1 -0.32 -4.7 -0.39 6.75e-6 Bipolar disorder and schizophrenia; TGCT cis rs6582630 0.574 rs12146797 chr12:38436499 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.7 0.57 3.77e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs2888674 1.000 rs2888674 chr7:150510915 G/A cg10409299 chr7:150498843 TMEM176B;TMEM176A 0.28 4.8 0.4 4.47e-6 Forced expiratory volume in 1 second (occupational environmental exposures interaction); TGCT cis rs727505 1.000 rs7790856 chr7:124459852 C/T cg23710748 chr7:124431027 NA -0.27 -4.54 -0.38 1.33e-5 Lewy body disease; TGCT cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg20637647 chr7:64974828 NA 0.88 5.34 0.43 4.19e-7 Diabetic kidney disease; TGCT cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs7264396 0.635 rs6060710 chr20:34536055 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.13 -0.42 1.1e-6 Total cholesterol levels; TGCT cis rs3743266 0.507 rs62003261 chr15:60761489 T/C cg18480781 chr15:60294291 NA 0.63 4.95 0.41 2.4e-6 Menarche (age at onset); TGCT cis rs12681288 0.676 rs6559208 chr8:1018833 A/G cg04851639 chr8:1020857 NA -0.34 -6.2 -0.49 7.82e-9 Schizophrenia; TGCT cis rs13191362 0.507 rs1079020 chr6:163066596 C/T cg06582575 chr6:163149167 PACRG;PARK2 -0.59 -5.45 -0.44 2.58e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2549003 1.000 rs2549007 chr5:131826875 T/C cg02551604 chr5:131831745 NA 0.9 11.87 0.73 3.59e-22 Asthma (sex interaction); TGCT cis rs7659604 0.540 rs67150579 chr4:122704331 T/A cg05802129 chr4:122689817 NA 0.3 4.51 0.38 1.45e-5 Type 2 diabetes; TGCT cis rs397020 0.904 rs203547 chr20:1195245 T/A cg03932398 chr20:1206703 RAD21L1 0.81 9.63 0.65 9.89e-17 Multiple sclerosis; TGCT cis rs2404602 0.647 rs2404604 chr15:76991105 A/G cg22467129 chr15:76604101 ETFA 0.48 4.73 0.39 5.9e-6 Blood metabolite levels; TGCT cis rs7213347 0.707 rs2038677 chr17:2178092 C/G cg20777128 chr17:1945076 DPH1;OVCA2 -0.5 -4.57 -0.38 1.17e-5 Total body bone mineral density; TGCT cis rs858239 0.509 rs6975524 chr7:23186452 T/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs3733585 0.699 rs4276278 chr4:9948870 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.43 -0.55 1.56e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs17376456 0.825 rs17314825 chr5:93234937 A/G cg09848695 chr5:92956644 FAM172A;MIR2277 0.79 5.05 0.41 1.54e-6 Diabetic retinopathy; TGCT cis rs7824557 0.701 rs4568582 chr8:11160495 A/T cg21775007 chr8:11205619 TDH 0.58 5.45 0.44 2.55e-7 Retinal vascular caliber; TGCT cis rs737008 0.821 rs28671554 chr16:11403753 A/G cg00044050 chr16:11439710 C16orf75 0.69 6.89 0.53 2.5e-10 Obesity-related traits; TGCT cis rs1153858 1.000 rs4775911 chr15:45649787 G/T cg26924012 chr15:45694286 SPATA5L1 -1.09 -15.16 -0.81 5.15e-30 Homoarginine levels; TGCT cis rs5167 0.601 rs892131 chr19:45496996 C/T cg09555818 chr19:45449301 APOC2 0.23 4.62 0.38 9.53e-6 Blood protein levels; TGCT cis rs554111 0.679 rs906254 chr1:21324760 G/A cg01072550 chr1:21505969 NA 0.35 5.35 0.43 4.11e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT trans rs7618501 0.519 rs3774749 chr3:50207227 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.79 -8.22 -0.59 2.36e-13 Intelligence (multi-trait analysis); TGCT cis rs394563 0.622 rs237024 chr6:149721965 T/C cg11245181 chr6:149772854 ZC3H12D -0.28 -4.52 -0.38 1.43e-5 Dupuytren's disease; TGCT cis rs875971 0.540 rs781152 chr7:65479572 T/A cg00343986 chr7:65444356 GUSB 0.24 5.41 0.44 3.13e-7 Aortic root size; TGCT cis rs1878931 0.507 rs1218762 chr16:3405986 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -5.19 -0.42 8.27e-7 Body mass index (adult); TGCT cis rs1215050 0.791 rs783969 chr4:98906504 C/T cg05340658 chr4:99064831 C4orf37 0.46 5.75 0.46 6.49e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs595982 0.559 rs4802516 chr19:49366170 T/C cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.25 -0.64 8.09e-16 Red cell distribution width; TGCT trans rs4512344 0.509 rs2409784 chr8:11396856 G/T cg06636001 chr8:8085503 FLJ10661 -0.7 -6.78 -0.52 4.34e-10 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT trans rs2469997 1.000 rs2447163 chr8:120373249 G/A cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs7917772 0.508 rs2252147 chr10:104467774 G/A cg05855489 chr10:104503620 C10orf26 -0.69 -5.67 -0.45 9.46e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9549367 0.713 rs553316 chr13:113838015 A/G cg18105134 chr13:113819100 PROZ 0.46 8.58 0.61 3.25e-14 Platelet distribution width; TGCT cis rs28785552 0.589 rs7257371 chr19:53243910 A/G cg22067481 chr19:53234126 ZNF611 -0.45 -6.39 -0.5 3.09e-9 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7772486 0.754 rs2064185 chr6:146066814 G/A cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2882877 0.610 rs13008848 chr2:190445284 C/G cg10752008 chr2:190445175 SLC40A1 0.78 6.16 0.48 9.3e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.73 -7.39 -0.55 1.92e-11 Prudent dietary pattern; TGCT cis rs9807989 0.839 rs7603730 chr2:102974371 A/C cg09003973 chr2:102972529 NA 0.66 5.89 0.47 3.46e-8 Asthma; TGCT cis rs10833905 0.680 rs11026907 chr11:23038698 T/C cg06387204 chr11:22647648 FANCF 0.52 4.77 0.39 5.01e-6 Sudden cardiac arrest; TGCT cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg03517284 chr6:25882590 NA -0.49 -4.51 -0.38 1.48e-5 Intelligence (multi-trait analysis); TGCT cis rs2549003 0.966 rs2706385 chr5:131831766 T/G cg21138405 chr5:131827807 IRF1 -0.18 -4.69 -0.39 7.11e-6 Asthma (sex interaction); TGCT cis rs4294134 0.608 rs11764262 chr7:135243932 T/G cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs4906332 0.966 rs12894275 chr14:103901424 A/G cg26031613 chr14:104095156 KLC1 0.53 4.72 0.39 6.2e-6 Coronary artery disease; TGCT cis rs7552404 0.924 rs1146588 chr1:76229787 C/G cg22875332 chr1:76189707 ACADM 0.69 8.32 0.6 1.32e-13 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs711245 0.545 rs848617 chr2:36811298 G/C cg15105969 chr2:36825350 FEZ2 0.52 4.52 0.38 1.44e-5 Height; TGCT cis rs10851411 0.862 rs2255995 chr15:42816868 A/C cg23803468 chr15:43513504 EPB42 -0.24 -4.56 -0.38 1.2e-5 Glucose homeostasis traits; TGCT cis rs1857353 1.000 rs2040080 chr1:75906724 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs9972944 0.729 rs1421033 chr17:63766714 A/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs8078723 1.000 rs4794823 chr17:38166265 A/T cg17467752 chr17:38218738 THRA 0.54 5.22 0.42 7.25e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg18305652 chr10:134549665 INPP5A 0.35 5.94 0.47 2.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs1814175 0.559 rs1818892 chr11:49863084 C/A cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs9527 0.545 rs7100369 chr10:104956218 C/A cg04362960 chr10:104952993 NT5C2 0.68 5.73 0.46 7.14e-8 Arsenic metabolism; TGCT trans rs7088591 0.702 rs10491208 chr10:59703352 C/G cg00178119 chr8:105235184 RIMS2 0.59 6.85 0.52 3.01e-10 Blood pressure; TGCT cis rs28595532 0.920 rs114213539 chr4:119758794 G/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs734999 1.000 rs10797432 chr1:2501338 C/T cg18854424 chr1:2615690 NA 0.45 5.5 0.44 2.05e-7 Ulcerative colitis; TGCT cis rs11030122 0.660 rs10835232 chr11:3900133 T/C cg18678763 chr11:4115507 RRM1 -0.35 -4.47 -0.37 1.71e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg04267008 chr7:1944627 MAD1L1 -0.35 -4.91 -0.4 2.76e-6 Bipolar disorder and schizophrenia; TGCT cis rs7267979 0.932 rs6037125 chr20:25463382 G/A cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1801251 0.644 rs283473 chr2:233654847 A/G cg25237894 chr2:233734115 C2orf82 0.26 4.83 0.4 3.9e-6 Coronary artery disease; TGCT cis rs813218 0.523 rs1708167 chr3:99459236 T/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.03 0.41 1.68e-6 Orofacial clefts; TGCT cis rs4851266 1.000 rs4303732 chr2:100830040 T/C cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs698813 0.674 rs4953080 chr2:44500849 C/A cg00619915 chr2:44497795 NA -0.22 -4.91 -0.4 2.79e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs7213347 0.707 rs4790323 chr17:2181658 A/G cg13315690 chr17:1944831 OVCA2;DPH1 -0.39 -4.95 -0.41 2.36e-6 Total body bone mineral density; TGCT cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.76 -0.46 6.11e-8 Coronary artery disease; TGCT cis rs478304 0.934 rs517115 chr11:65526988 C/T cg27068330 chr11:65405492 SIPA1 0.75 7.57 0.56 7.2e-12 Acne (severe); TGCT cis rs1395 1.000 rs3769143 chr2:27450724 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.5 -6.73 -0.52 5.69e-10 Blood metabolite levels; TGCT cis rs367615 0.704 rs4286723 chr5:108835959 G/A cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs11209002 0.567 rs983111 chr1:67539356 T/C cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs9611565 0.649 rs2413659 chr22:42164862 A/G cg13695892 chr22:41940480 POLR3H 0.79 7.5 0.56 1.08e-11 Vitiligo; TGCT cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Vitiligo; TGCT cis rs7027203 0.576 rs7874836 chr9:96559370 C/T cg14396892 chr9:96623032 NA -0.25 -5.0 -0.41 1.94e-6 DNA methylation (variation); TGCT cis rs10992471 0.580 rs13284106 chr9:95433845 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -4.89 -0.4 3.04e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9902453 1.000 rs9890205 chr17:28382704 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs3087591 0.708 rs35109242 chr17:29649223 A/G cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT cis rs7666738 0.830 rs1559859 chr4:99024325 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.74 5.28 0.43 5.62e-7 Platelet count; TGCT cis rs9303401 0.659 rs72828726 chr17:56951217 C/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs7611238 0.560 rs7632534 chr3:194998493 G/T cg27323046 chr3:195102265 ACAP2 0.36 4.73 0.39 5.89e-6 Body mass index; TGCT cis rs208520 0.837 rs208467 chr6:66914837 T/C cg07460842 chr6:66804631 NA -0.9 -9.16 -0.64 1.34e-15 Exhaled nitric oxide output; TGCT cis rs11785400 1.000 rs7002932 chr8:143738816 C/A cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs939574 1.000 rs3817424 chr2:220096903 A/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.06 6.52 0.51 1.6e-9 Platelet distribution width; TGCT cis rs2820315 0.867 rs2820319 chr1:201878650 G/A cg12730843 chr1:201915899 LMOD1 -0.28 -5.12 -0.42 1.14e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs6952808 0.964 rs10950400 chr7:1882470 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.62 -0.45 1.2e-7 Bipolar disorder and schizophrenia; TGCT cis rs77633900 0.614 rs2629025 chr15:76943363 G/C cg21673338 chr15:77095150 SCAPER -0.52 -4.92 -0.4 2.72e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs7824557 0.592 rs920044 chr8:11224313 C/T cg21775007 chr8:11205619 TDH 0.64 5.95 0.47 2.59e-8 Retinal vascular caliber; TGCT cis rs9952991 0.941 rs45450798 chr18:12792940 C/G cg23598886 chr18:12777645 NA -0.61 -5.45 -0.44 2.62e-7 Inflammatory skin disease; TGCT cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs208520 1.000 rs208527 chr6:66957209 A/C cg07460842 chr6:66804631 NA -0.83 -7.52 -0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7904368 0.806 rs1130684 chr10:16859335 C/G cg23933602 chr10:16859644 RSU1 0.61 4.52 0.38 1.43e-5 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs950027 0.549 rs11636114 chr15:45601412 C/G cg14582100 chr15:45693742 SPATA5L1 0.5 6.1 0.48 1.25e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs2028201 0.900 rs4674068 chr2:201306139 A/G cg04781494 chr2:202047246 CASP10 0.24 4.44 0.37 1.97e-5 Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis; TGCT cis rs1062177 1.000 rs17804178 chr5:151197729 T/G cg00977110 chr5:151150581 G3BP1 0.4 4.5 0.38 1.51e-5 Preschool internalizing problems; TGCT cis rs2880765 0.835 rs7168860 chr15:86037030 G/A cg13263323 chr15:86062960 AKAP13 -0.22 -4.84 -0.4 3.84e-6 Coronary artery disease; TGCT cis rs7819412 0.744 rs6601562 chr8:10962929 G/C cg21775007 chr8:11205619 TDH -0.5 -4.79 -0.4 4.64e-6 Triglycerides; TGCT cis rs12200560 0.505 rs211182 chr6:97074513 G/A cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs548181 0.545 rs76179820 chr11:125616379 A/G cg03464685 chr11:125439445 EI24 -1.3 -7.93 -0.58 1.12e-12 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7937682 0.889 rs10749984 chr11:111492861 T/C cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs4820792 0.623 rs743185 chr22:29103217 G/A cg03733026 chr22:29445468 ZNRF3 0.26 4.9 0.4 2.94e-6 Breast size; TGCT cis rs17253792 0.822 rs75232282 chr14:56067290 G/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs2836950 0.545 rs8132424 chr21:40584412 A/T cg11890956 chr21:40555474 PSMG1 0.68 6.67 0.51 7.51e-10 Menarche (age at onset); TGCT cis rs6496667 0.565 rs7162107 chr15:90889046 A/G cg22089800 chr15:90895588 ZNF774 0.63 5.53 0.44 1.81e-7 Rheumatoid arthritis; TGCT cis rs12935418 0.616 rs62054213 chr16:80968203 G/C cg07676361 chr16:80966860 NA -0.35 -4.6 -0.38 1.02e-5 Mean corpuscular volume; TGCT cis rs1903068 0.819 rs10517343 chr4:56002267 T/A cg01777861 chr4:56023843 NA 0.54 6.38 0.5 3.2e-9 Endometriosis; TGCT cis rs2486012 0.737 rs37468 chr1:44280381 A/T cg12908607 chr1:44402522 ARTN 0.72 5.68 0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs11100 chr20:25281184 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7674212 0.539 rs6815783 chr4:104122146 A/C cg16532752 chr4:104119610 CENPE -0.6 -5.46 -0.44 2.51e-7 Type 2 diabetes; TGCT cis rs4566357 0.595 rs1320406 chr2:227920474 C/T cg11843606 chr2:227700838 RHBDD1 -0.51 -4.78 -0.39 4.97e-6 Coronary artery disease; TGCT cis rs1552244 0.816 rs13076197 chr3:10019773 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs3820068 0.608 rs7519899 chr1:16045579 A/G cg17385448 chr1:15911702 AGMAT 0.35 4.63 0.38 8.97e-6 Systolic blood pressure; TGCT cis rs57994353 0.632 rs68142670 chr9:139324573 T/C cg13741927 chr9:139327495 INPP5E -0.27 -6.14 -0.48 1.01e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9583531 0.600 rs9521909 chr13:111362170 A/G cg24331049 chr13:111365604 ING1 0.76 7.31 0.55 2.95e-11 Coronary artery disease; TGCT cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs1670533 0.818 rs643484 chr4:1085826 A/G cg20887711 chr4:1340912 KIAA1530 0.66 5.33 0.43 4.49e-7 Recombination rate (females); TGCT cis rs2282802 0.685 rs11748023 chr5:139558584 C/T cg01081189 chr5:139537190 NA -0.3 -5.37 -0.43 3.82e-7 Intelligence (multi-trait analysis); TGCT cis rs75686122 0.892 rs79054943 chr8:104601404 A/G cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs1667284 1.000 rs1612691 chr18:29220918 A/G cg15259973 chr18:29078565 DSG2 0.53 5.19 0.42 8.27e-7 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs35306767 0.903 rs12240651 chr10:943656 A/G cg20503657 chr10:835505 NA 0.75 10.55 0.69 5.67e-19 Eosinophil percentage of granulocytes; TGCT cis rs8014204 0.901 rs4899536 chr14:75316614 A/G cg06637938 chr14:75390232 RPS6KL1 -0.72 -6.83 -0.52 3.32e-10 Caffeine consumption; TGCT cis rs9581857 0.685 rs9319370 chr13:28042493 G/T cg22138327 chr13:27999177 GTF3A 0.72 4.6 0.38 1.03e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6969780 0.722 rs985652 chr7:27198083 A/C cg04321618 chr7:27170880 HOXA4 -0.52 -5.15 -0.42 9.77e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6835098 0.692 rs28701033 chr4:174079376 T/A cg08422745 chr4:174089978 GALNT7 -0.77 -8.6 -0.61 2.87e-14 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs736408 0.570 rs11130327 chr3:52793239 A/G cg10802521 chr3:52805072 NEK4 -0.74 -8.94 -0.63 4.47e-15 Bipolar disorder; TGCT cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg21951975 chr1:209979733 IRF6 0.7 6.01 0.47 1.92e-8 Cleft lip with or without cleft palate; TGCT cis rs6671200 0.607 rs3767313 chr1:95712797 G/A cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs968567 0.539 rs174555 chr11:61579760 T/C cg01500311 chr11:61656094 FADS3 -0.29 -4.98 -0.41 2.1e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs7937682 1.000 rs11608149 chr11:111535102 G/A cg09085632 chr11:111637200 PPP2R1B 1.03 9.46 0.65 2.53e-16 Primary sclerosing cholangitis; TGCT cis rs6495367 0.898 rs2049176 chr15:79392548 A/C cg17916960 chr15:79447300 NA 0.37 5.44 0.44 2.71e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7586879 0.616 rs11900505 chr2:25131986 A/C cg01884057 chr2:25150051 NA 0.36 7.1 0.54 8.43e-11 Body mass index; TGCT cis rs7169223 0.653 rs1976007 chr15:79085023 T/C cg03762349 chr15:79060523 ADAMTS7 -0.24 -5.0 -0.41 1.92e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs3796352 1.000 rs11713206 chr3:52999243 A/G cg15956490 chr3:53032818 SFMBT1 0.61 6.11 0.48 1.17e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg21724239 chr8:58056113 NA 0.49 5.15 0.42 9.92e-7 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.8e-6 Obesity-related traits; TGCT cis rs7524258 0.868 rs4908451 chr1:7299618 C/G cg04342483 chr1:7259290 CAMTA1 0.31 4.57 0.38 1.17e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs6542838 0.609 rs12712043 chr2:99541494 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.55 -5.25 -0.43 6.43e-7 Fear of minor pain; TGCT cis rs9486719 0.843 rs1009597 chr6:96843540 A/T cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs68170813 0.559 rs76534758 chr7:106963262 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs734999 0.967 rs10910089 chr1:2498618 G/T cg18854424 chr1:2615690 NA 0.45 5.57 0.45 1.5e-7 Ulcerative colitis; TGCT cis rs597539 0.652 rs654071 chr11:68653432 A/C cg06112835 chr11:68658793 MRPL21 0.47 8.03 0.59 6.25e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs6089829 0.962 rs6089825 chr20:61668447 C/T cg23505145 chr19:12996616 KLF1 0.87 9.61 0.65 1.09e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs11122272 0.735 rs2486740 chr1:231517552 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs7193541 0.564 rs4888274 chr16:74706298 A/T cg01733217 chr16:74700730 RFWD3 1.0 13.58 0.77 2.66e-26 Multiple myeloma; TGCT cis rs5769707 1.000 rs5769707 chr22:50013402 G/T cg10356904 chr22:49881777 NA -0.23 -4.67 -0.39 7.64e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs114540395 0.925 rs7090062 chr10:103408014 A/G cg03300883 chr10:102748874 C10orf2 0.43 4.5 0.37 1.52e-5 Schizophrenia; TGCT cis rs621559 0.681 rs11210796 chr1:43627976 C/T cg01614716 chr1:43834120 ELOVL1 -0.91 -4.46 -0.37 1.82e-5 Telomere length; TGCT cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg13607699 chr17:42295918 UBTF 0.6 5.47 0.44 2.35e-7 Total body bone mineral density; TGCT cis rs7208859 0.573 rs11654035 chr17:29136426 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.66e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7119 0.651 rs17394732 chr15:77835657 A/G cg27398640 chr15:77910606 LINGO1 0.27 5.12 0.42 1.15e-6 Type 2 diabetes; TGCT trans rs853356 0.843 rs4441955 chr6:14182725 G/A cg14262035 chr17:42019790 PPY 0.51 6.79 0.52 4.21e-10 Height; TGCT cis rs9858542 0.953 rs6766581 chr3:49539401 T/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7523050 0.730 rs12729728 chr1:109431110 C/A cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs10992471 0.580 rs10992366 chr9:95317214 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.67 -0.45 9.37e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6663390 0.510 rs2267897 chr1:208075378 C/T cg03990033 chr1:208084030 CD34 0.73 6.41 0.5 2.77e-9 Facial morphology (factor 18); TGCT cis rs9300255 0.602 rs1790116 chr12:123618544 G/T cg00376283 chr12:123451042 ABCB9 0.67 5.27 0.43 5.78e-7 Neutrophil percentage of white cells; TGCT cis rs8016982 0.674 rs61980899 chr14:81676844 T/C cg01989461 chr14:81687754 GTF2A1 0.8 8.26 0.6 1.89e-13 Schizophrenia; TGCT cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg11905131 chr22:24372483 LOC391322 -0.69 -6.1 -0.48 1.25e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1670533 0.818 rs585735 chr4:1080391 G/C cg20887711 chr4:1340912 KIAA1530 0.7 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs1218582 0.804 rs4845678 chr1:154853295 A/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.31 -0.55 2.89e-11 Prostate cancer; TGCT trans rs7618501 0.571 rs2240329 chr3:50107512 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs34779708 0.931 rs11592404 chr10:35273476 G/A cg04310649 chr10:35416472 CREM -0.51 -4.54 -0.38 1.31e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs651907 0.514 rs12636046 chr3:101434448 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.73 0.39 5.91e-6 Colorectal cancer; TGCT cis rs2836974 0.899 rs2836957 chr21:40623134 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.47 0.5 2.08e-9 Cognitive function; TGCT cis rs11696501 0.688 rs8123346 chr20:44309987 A/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs1023500 0.552 rs5758566 chr22:42454354 G/A cg05082376 chr22:42548792 NA -0.21 -4.93 -0.4 2.63e-6 Schizophrenia; TGCT cis rs17376456 0.825 rs17314825 chr5:93234937 A/G cg25358565 chr5:93447407 FAM172A 1.08 8.3 0.6 1.48e-13 Diabetic retinopathy; TGCT cis rs921968 0.643 rs864990 chr2:219494037 G/A cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7223966 1.000 rs8075521 chr17:61804954 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs6912958 0.703 rs6903219 chr6:88096498 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.4 5.22 0.42 7.22e-7 Monocyte percentage of white cells; TGCT cis rs2456568 0.741 rs9633811 chr11:93628327 A/G cg26875233 chr11:93583750 C11orf90 0.47 6.36 0.5 3.48e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs12142240 0.659 rs1984491 chr1:46858607 T/G cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs7119 0.651 rs12905044 chr15:77846215 G/A cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs2836974 0.932 rs35571600 chr21:40590624 A/C cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.67e-16 Cognitive function; TGCT cis rs7772486 0.754 rs9390356 chr6:146118983 A/T cg23711669 chr6:146136114 FBXO30 -0.93 -10.49 -0.69 8.22e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6840360 0.593 rs3805356 chr4:152680701 C/T cg22705602 chr4:152727874 NA 0.34 5.88 0.47 3.57e-8 Intelligence (multi-trait analysis); TGCT cis rs2017387 0.572 rs157547 chr19:50495082 C/T cg19230443 chr19:49950584 PIH1D1 -0.28 -4.62 -0.38 9.5e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9858542 0.537 rs9873994 chr3:49359943 T/C cg00383909 chr3:49044727 WDR6 0.67 4.56 0.38 1.19e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs12477438 0.765 rs1453564 chr2:99564428 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs35306767 0.903 rs11253462 chr10:889323 T/G cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs7772486 0.754 rs2328709 chr6:146106819 A/G cg13319975 chr6:146136371 FBXO30 0.6 5.42 0.44 2.97e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.08 0.42 1.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs801193 1.000 rs2420824 chr7:66131116 G/A cg18876405 chr7:65276391 NA -0.39 -5.92 -0.47 3e-8 Aortic root size; TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg22166914 chr1:53195759 ZYG11B 0.33 5.33 0.43 4.4e-7 Monocyte count; TGCT cis rs7223966 1.000 rs28463311 chr17:61919643 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs473651 0.935 rs474478 chr2:239335473 C/T cg21699342 chr2:239360505 ASB1 0.18 5.01 0.41 1.8e-6 Multiple system atrophy; TGCT cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg26531700 chr6:26746687 NA 0.52 5.01 0.41 1.8e-6 Intelligence (multi-trait analysis); TGCT cis rs2576037 0.583 rs530205 chr18:44385150 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.61 -0.38 9.88e-6 Personality dimensions; TGCT cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs7666738 0.830 rs12233741 chr4:98950296 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.791 rs9376945 chr6:145828080 T/A cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7567389 0.600 rs3732209 chr2:128079806 A/G cg09760422 chr2:128146352 NA 0.39 5.18 0.42 8.76e-7 Self-rated health; TGCT cis rs854765 0.505 rs4506969 chr17:17899839 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.08 0.59 4.9e-13 Total body bone mineral density; TGCT cis rs79349575 0.783 rs4794003 chr17:47029904 C/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT trans rs4650994 0.525 rs4457535 chr1:178497186 C/T cg05059571 chr16:84539110 KIAA1609 0.54 11.23 0.71 1.27e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs4665809 0.590 rs9309474 chr2:26448830 T/A cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs9911578 1.000 rs391370 chr17:56675050 A/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.3 -0.49 4.84e-9 Intelligence (multi-trait analysis); TGCT cis rs3011225 0.691 rs3791102 chr1:44366617 C/T cg13606994 chr1:44402422 ARTN -0.42 -4.56 -0.38 1.22e-5 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs2404602 1.000 rs1117367 chr15:76872330 A/C cg26408565 chr15:76604113 ETFA -0.38 -4.88 -0.4 3.24e-6 Blood metabolite levels; TGCT cis rs13177918 0.677 rs13164105 chr5:149826066 T/A cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7937682 0.883 rs631490 chr11:111452040 G/C cg09085632 chr11:111637200 PPP2R1B -0.99 -10.36 -0.68 1.64e-18 Primary sclerosing cholangitis; TGCT cis rs2276314 0.857 rs72883058 chr18:33612917 G/A cg19628046 chr18:33552617 C18orf21 0.51 4.46 0.37 1.79e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs782590 0.764 rs2586969 chr2:55829392 G/C cg03859395 chr2:55845619 SMEK2 0.84 10.09 0.67 7.69e-18 Metabolic syndrome; TGCT cis rs7698623 0.850 rs6532020 chr4:88768928 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs6912958 0.874 rs9294381 chr6:88152681 A/T cg12350822 chr6:88032061 C6orf162;GJB7 -0.36 -4.55 -0.38 1.28e-5 Monocyte percentage of white cells; TGCT cis rs12682352 0.579 rs7006589 chr8:8668486 A/G cg06636001 chr8:8085503 FLJ10661 0.57 4.89 0.4 3.04e-6 Neuroticism; TGCT cis rs9393777 0.513 rs7759969 chr6:26663096 T/A cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs34065801 0.526 rs8001225 chr13:36514506 C/A cg03563146 chr13:37393157 RFXAP 0.5 4.84 0.4 3.78e-6 Breast size; TGCT cis rs950169 0.922 rs17531523 chr15:85132449 C/G cg11189052 chr15:85197271 WDR73 0.78 6.49 0.5 1.88e-9 Schizophrenia; TGCT cis rs875971 1.000 rs11974219 chr7:65647410 C/T cg11764359 chr7:65958608 NA -0.6 -5.32 -0.43 4.68e-7 Aortic root size; TGCT cis rs367615 0.704 rs6889301 chr5:108835181 C/T cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2271316 0.587 rs11078659 chr17:6903944 G/A cg03407747 chr17:6899364 ALOX12 0.43 4.74 0.39 5.86e-6 Blood metabolite levels; TGCT cis rs9611565 0.729 rs505533 chr22:41864216 A/C cg13695892 chr22:41940480 POLR3H 0.86 8.55 0.61 3.95e-14 Vitiligo; TGCT cis rs56399783 0.614 rs55776032 chr7:2762255 T/C cg19731401 chr7:2775893 GNA12 0.38 5.34 0.43 4.22e-7 Childhood ear infection; TGCT cis rs1048238 0.846 rs945419 chr1:16344858 C/T cg22431228 chr1:16359049 CLCNKA -0.29 -6.2 -0.49 7.76e-9 Systolic blood pressure; TGCT cis rs10791097 0.720 rs7119425 chr11:130733185 C/T cg12179176 chr11:130786555 SNX19 0.81 9.98 0.67 1.43e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6582630 0.502 rs11182760 chr12:38606273 A/T cg13010199 chr12:38710504 ALG10B 0.66 5.18 0.42 8.76e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs2120019 0.938 rs35911108 chr15:75322179 G/A cg09165964 chr15:75287851 SCAMP5 -1.14 -10.33 -0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs4819052 0.851 rs2838864 chr21:46711474 A/T cg19498844 chr21:46707878 POFUT2;LOC642852 -0.78 -7.34 -0.55 2.45e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs17450420 1.000 rs10508146 chr13:105056807 C/T cg14737571 chr13:113436568 ATP11A 0.61 6.64 0.51 8.8e-10 Esophageal cancer (alcohol interaction); TGCT cis rs72949976 0.646 rs4673731 chr2:214028544 C/T cg08319019 chr2:214017104 IKZF2 0.87 8.64 0.61 2.34e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs514406 0.763 rs9988539 chr1:53213884 T/C cg16325326 chr1:53192061 ZYG11B -0.74 -9.11 -0.63 1.79e-15 Monocyte count; TGCT cis rs11648796 0.765 rs2003832 chr16:769538 G/A cg07343612 chr16:622815 PIGQ -0.38 -5.29 -0.43 5.39e-7 Height; TGCT cis rs80033912 0.713 rs7629936 chr3:49836707 G/A cg07636037 chr3:49044803 WDR6 0.6 4.91 0.4 2.79e-6 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg05738196 chr6:26577821 NA 0.87 10.75 0.69 1.87e-19 Intelligence (multi-trait analysis); TGCT cis rs7226408 0.857 rs72885245 chr18:34425458 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.83 0.4 4.02e-6 Obesity-related traits; TGCT cis rs425277 0.958 rs262652 chr1:2090816 T/C cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg04025307 chr7:1156635 C7orf50 0.23 5.43 0.44 2.85e-7 Longevity;Endometriosis; TGCT cis rs751728 1.000 rs4342423 chr6:33732679 C/T cg13859433 chr6:33739653 LEMD2 -0.39 -7.43 -0.56 1.5e-11 Crohn's disease; TGCT cis rs4689388 0.889 rs13101355 chr4:6293446 T/C cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9527 0.590 rs11191544 chr10:104827198 C/G cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs2147959 0.766 rs35362491 chr1:228782552 C/A cg22700015 chr1:228743131 NA 0.58 5.02 0.41 1.71e-6 Adult asthma; TGCT cis rs7953249 0.542 rs1169284 chr12:121419926 T/C cg02403541 chr12:121454288 C12orf43 0.65 5.63 0.45 1.15e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs478607 1.000 rs551890 chr11:64477999 C/T cg19395706 chr11:64412079 NRXN2 -0.47 -5.02 -0.41 1.72e-6 Urate levels; TGCT cis rs2243480 0.901 rs34807232 chr7:65965133 G/A cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs10892173 0.566 rs2298649 chr11:117672225 A/G cg07621104 chr11:117668040 DSCAML1 0.73 7.95 0.58 9.58e-13 Myopia; TGCT cis rs459571 1.000 rs2810489 chr9:136922700 C/T cg13789015 chr9:136890014 NCRNA00094 0.39 6.65 0.51 8.54e-10 Platelet distribution width; TGCT cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg06634786 chr22:41940651 POLR3H -0.9 -8.93 -0.63 4.7e-15 Vitiligo; TGCT cis rs9303401 0.538 rs8078280 chr17:56473132 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.54 5.28 0.43 5.53e-7 Cognitive test performance; TGCT cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg18230493 chr5:56204884 C5orf35 0.86 6.85 0.52 3.08e-10 Initial pursuit acceleration; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg14159672 chr1:205819179 PM20D1 0.63 7.92 0.58 1.16e-12 Menarche (age at onset); TGCT cis rs2576037 0.583 rs12386118 chr18:44540376 C/G cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.78 -0.39 4.94e-6 Personality dimensions; TGCT cis rs12039431 0.788 rs58284750 chr1:38042926 C/A cg17933807 chr1:38061675 GNL2 -0.81 -8.0 -0.58 7.58e-13 Epithelial ovarian cancer; TGCT cis rs2832191 1.000 rs2832191 chr21:30489300 A/C cg24692254 chr21:30365293 RNF160 -0.82 -8.73 -0.62 1.43e-14 Dental caries; TGCT cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg03609598 chr5:56110824 MAP3K1 -0.66 -4.64 -0.38 8.89e-6 Initial pursuit acceleration; TGCT cis rs7666738 0.830 rs34212748 chr4:99068708 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.806 rs13139898 chr4:17706928 T/G cg18681998 chr4:17616180 MED28 -0.83 -8.36 -0.6 1.09e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.862 rs9791712 chr7:66105163 C/G cg11764359 chr7:65958608 NA -0.55 -4.98 -0.41 2.1e-6 Aortic root size; TGCT cis rs57244997 0.860 rs9458425 chr6:162376946 C/T cg17173639 chr6:162384350 PARK2 -0.48 -5.27 -0.43 5.87e-7 Mosquito bite size; TGCT cis rs236907 0.859 rs35631282 chr1:171760682 C/T cg20598894 chr1:171756153 METTL13 -0.2 -4.54 -0.38 1.31e-5 Mean platelet volume; TGCT cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2932538 0.922 rs12125361 chr1:113144779 C/T cg22162597 chr1:113214053 CAPZA1 0.27 5.9 0.47 3.31e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7208859 0.673 rs9911989 chr17:29237702 A/C cg14008862 chr17:28927542 LRRC37B2 -0.76 -4.95 -0.41 2.35e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs968451 1.000 rs1569495 chr22:39665142 G/C cg17798944 chr22:39715225 SNORD43;RPL3 0.78 6.76 0.52 4.85e-10 Primary biliary cholangitis; TGCT cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.6 5.5 0.44 2.04e-7 Colorectal cancer; TGCT cis rs1008375 0.863 rs10003291 chr4:17600728 A/C cg18681998 chr4:17616180 MED28 0.94 8.59 0.61 3.17e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10779751 0.770 rs2258621 chr1:11141187 C/G cg08854313 chr1:11322531 MTOR 0.85 6.96 0.53 1.74e-10 Body mass index; TGCT cis rs2153535 0.601 rs4140585 chr6:8503298 T/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs763121 0.853 rs2281019 chr22:39064378 T/A cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs9467773 1.000 rs2224380 chr6:26553943 G/A cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.558 rs7305397 chr12:42850058 T/C cg19980929 chr12:42632907 YAF2 0.43 6.1 0.48 1.23e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4654899 0.802 rs7519685 chr1:21192623 G/A cg01072550 chr1:21505969 NA -0.47 -7.09 -0.54 8.84e-11 Superior frontal gyrus grey matter volume; TGCT cis rs7567389 0.600 rs11679414 chr2:128151003 G/A cg02161262 chr2:127865248 BIN1 0.52 4.64 0.38 8.54e-6 Self-rated health; TGCT cis rs9911578 0.874 rs302874 chr17:56767996 A/G cg05425664 chr17:57184151 TRIM37 -0.66 -6.58 -0.51 1.18e-9 Intelligence (multi-trait analysis); TGCT cis rs769267 0.929 rs2905431 chr19:19482882 G/A cg03709012 chr19:19516395 GATAD2A -0.77 -6.49 -0.5 1.86e-9 Tonsillectomy; TGCT cis rs13102973 0.720 rs13137075 chr4:135889366 G/A cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs1278769 0.786 rs3742238 chr13:113540425 C/T cg17842918 chr13:113540400 ATP11A -0.32 -4.48 -0.37 1.67e-5 Interstitial lung disease; TGCT cis rs71636778 0.509 rs34514856 chr1:27287560 G/T cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs9916302 0.861 rs12150493 chr17:37586154 T/C cg07936489 chr17:37558343 FBXL20 -0.61 -4.81 -0.4 4.27e-6 Glomerular filtration rate (creatinine); TGCT cis rs875971 1.000 rs6958277 chr7:65979349 A/G cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs1218582 0.772 rs2102423 chr1:154916068 A/G cg03351412 chr1:154909251 PMVK 0.51 4.82 0.4 4.18e-6 Prostate cancer; TGCT cis rs6912958 0.781 rs2284908 chr6:88194500 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.08 -0.41 1.36e-6 Monocyte percentage of white cells; TGCT cis rs17376456 0.877 rs10514380 chr5:93409370 C/T cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs986417 0.818 rs10133871 chr14:61063771 A/C cg27398547 chr14:60952738 C14orf39 1.33 9.93 0.67 1.82e-17 Gut microbiota (bacterial taxa); TGCT cis rs2120019 0.938 rs8028632 chr15:75321262 T/C cg11632617 chr15:75315747 PPCDC -0.3 -4.44 -0.37 1.95e-5 Blood trace element (Zn levels); TGCT cis rs7772486 0.790 rs9497427 chr6:146238302 T/A cg23711669 chr6:146136114 FBXO30 -0.85 -9.7 -0.66 6.73e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7178572 0.568 rs12914345 chr15:77670401 A/C cg15453836 chr15:77711506 NA -0.41 -4.68 -0.39 7.43e-6 Type 2 diabetes; TGCT cis rs28595532 1.000 rs28600971 chr4:119712728 G/T cg14228332 chr4:119757509 SEC24D 0.9 4.91 0.4 2.82e-6 Cannabis dependence symptom count; TGCT cis rs3764400 0.567 rs16951519 chr17:46152291 G/A cg02340556 chr17:46797764 NA 0.41 4.47 0.37 1.72e-5 Body mass index; TGCT cis rs11190604 1.000 rs11292 chr10:102313607 A/G cg16342193 chr10:102329863 NA -0.41 -5.21 -0.42 7.68e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs950027 0.620 rs2461700 chr15:45640627 T/C cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs6725041 0.819 rs10175497 chr2:213082649 A/G cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs2836950 0.545 rs2836940 chr21:40588696 T/C cg11644478 chr21:40555479 PSMG1 -0.52 -4.84 -0.4 3.83e-6 Menarche (age at onset); TGCT cis rs7666738 0.830 rs7698771 chr4:98986479 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs2832191 0.791 rs2832182 chr21:30481612 G/A cg08807101 chr21:30365312 RNF160 -0.66 -6.19 -0.49 8.16e-9 Dental caries; TGCT cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.6 -0.38 1.01e-5 Schizophrenia; TGCT cis rs9311474 0.713 rs352166 chr3:52238677 C/T cg07507251 chr3:52567010 NT5DC2 0.42 5.7 0.46 8.37e-8 Electroencephalogram traits; TGCT cis rs2723064 0.543 rs2080385 chr2:65292762 G/T cg05010058 chr2:65284262 CEP68 0.56 5.76 0.46 6.34e-8 Atrial fibrillation; TGCT cis rs9814567 0.929 rs1863912 chr3:134205227 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -9.97 -0.67 1.5e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4664308 1.000 rs62175515 chr2:160909524 A/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs2730260 0.537 rs56023468 chr7:158875329 T/C cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs9399135 0.933 rs4559100 chr6:135324085 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg13695892 chr22:41940480 POLR3H 0.93 9.1 0.63 1.88e-15 Vitiligo; TGCT cis rs1847202 0.859 rs11923247 chr3:72923306 A/G cg25664220 chr3:72788482 NA -0.38 -4.88 -0.4 3.13e-6 Motion sickness; TGCT cis rs7586879 0.593 rs6733224 chr2:25130907 C/T cg15423357 chr2:25149977 NA -0.48 -4.65 -0.39 8.28e-6 Body mass index; TGCT cis rs4499344 0.769 rs114289041 chr19:33083746 A/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.71 -6.33 -0.49 4.12e-9 Mean platelet volume; TGCT cis rs8077889 0.957 rs17742929 chr17:41891437 C/T cg25876840 chr17:41920477 NA 0.24 4.59 0.38 1.09e-5 Triglycerides; TGCT cis rs17601876 0.814 rs2414101 chr15:51562434 A/G cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs6964587 1.000 rs17164275 chr7:91590408 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs8177253 1.000 rs1525892 chr3:133484712 C/T cg11941060 chr3:133502564 NA -0.29 -6.17 -0.48 8.85e-9 Iron status biomarkers; TGCT trans rs9388451 0.626 rs7748729 chr6:126077381 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.85 -9.81 -0.66 3.6e-17 Brugada syndrome; TGCT cis rs597539 0.617 rs669659 chr11:68635623 G/C cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2455799 0.559 rs2121737 chr3:15907946 C/G cg12172478 chr3:16357591 RFTN1 0.36 5.08 0.41 1.37e-6 Mean platelet volume; TGCT cis rs2013441 1.000 rs1992562 chr17:20218793 A/C cg23224458 chr17:20280056 CCDC144C -0.37 -4.46 -0.37 1.78e-5 Obesity-related traits; TGCT cis rs3027009 0.881 rs61828174 chr1:159134846 T/A cg18972751 chr1:158261555 CD1C -0.42 -4.52 -0.38 1.4e-5 Lean body mass and age at menarche (combined); TGCT cis rs6831352 0.918 rs13113166 chr4:100050528 A/G cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs9388451 0.626 rs1935983 chr6:126068914 C/T cg05901451 chr6:126070800 HEY2 -1.04 -13.0 -0.76 6.65e-25 Brugada syndrome; TGCT trans rs877282 0.853 rs7079450 chr10:755932 T/A cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs1488864 1.000 rs10742972 chr11:6347128 G/T cg12755421 chr11:6342214 PRKCDBP -0.56 -4.48 -0.37 1.7e-5 Smooth-surface caries; TGCT cis rs1799949 1.000 rs8176318 chr17:41197274 G/T cg05368731 chr17:41323189 NBR1 1.05 10.39 0.68 1.45e-18 Menopause (age at onset); TGCT cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg11890956 chr21:40555474 PSMG1 -0.77 -7.6 -0.56 6.17e-12 Cognitive function; TGCT cis rs7010267 0.596 rs6999476 chr8:120032259 C/G cg17171407 chr8:119960777 TNFRSF11B 0.25 4.49 0.37 1.59e-5 Total body bone mineral density (age 45-60); TGCT cis rs739496 0.615 rs3742001 chr12:112103148 C/T cg10833066 chr12:111807467 FAM109A 0.35 5.18 0.42 8.83e-7 Platelet count; TGCT cis rs17376456 0.877 rs10064520 chr5:93427358 T/C cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs28595532 0.920 rs56302600 chr4:119770162 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs7949030 0.626 rs11231141 chr11:62326265 T/C cg22862634 chr11:62369728 EML3;MTA2 0.71 9.06 0.63 2.4e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg03303774 chr4:1407052 NA -0.32 -4.92 -0.4 2.7e-6 Obesity-related traits; TGCT cis rs1023500 0.573 rs133382 chr22:42471774 C/T cg15557168 chr22:42548783 NA -0.22 -5.58 -0.45 1.47e-7 Schizophrenia; TGCT cis rs2034088 0.619 rs4968170 chr17:404712 T/C cg01214346 chr17:406501 NA -0.36 -5.48 -0.44 2.25e-7 Hip circumference adjusted for BMI; TGCT cis rs9309473 0.718 rs10175529 chr2:73606093 A/G cg20560298 chr2:73613845 ALMS1 -0.44 -4.86 -0.4 3.52e-6 Metabolite levels; TGCT cis rs7267979 1.000 rs2258769 chr20:25276680 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13217239 0.646 rs10456351 chr6:26986792 C/T cg15659132 chr6:26577336 NA 0.55 5.55 0.45 1.62e-7 Schizophrenia; TGCT cis rs1799949 0.930 rs2298861 chr17:41176831 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs1371867 0.846 rs1788199 chr8:101292854 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs3847687 1.000 rs10848269 chr12:131518622 A/G cg13586425 chr12:131519906 GPR133 -0.33 -5.0 -0.41 1.87e-6 Longevity; TGCT cis rs1153858 1.000 rs4775907 chr15:45638647 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs7191700 0.644 rs12149160 chr16:11439303 G/T cg00044050 chr16:11439710 C16orf75 -0.88 -10.43 -0.68 1.16e-18 Multiple sclerosis; TGCT cis rs12134133 0.962 rs2564970 chr1:207464041 C/A cg02152968 chr1:207494213 CD55 0.57 4.47 0.37 1.74e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs4925386 0.759 rs2427293 chr20:60925859 A/G cg06026331 chr20:60912101 LAMA5 -0.37 -5.98 -0.47 2.25e-8 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs11098499 0.754 rs7672594 chr4:120248543 A/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9858542 0.953 rs6809216 chr3:49412559 G/A cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7666738 0.791 rs7657399 chr4:98851861 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 1.000 rs884977 chr7:1066410 T/C cg18402987 chr7:1209562 NA 0.67 5.43 0.44 2.86e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3820068 0.529 rs79570154 chr1:15990912 T/C cg05660106 chr1:15850417 CASP9 0.79 7.22 0.54 4.55e-11 Systolic blood pressure; TGCT cis rs17376456 0.778 rs10476604 chr5:93461838 C/T cg25358565 chr5:93447407 FAM172A 0.64 6.04 0.48 1.63e-8 Diabetic retinopathy; TGCT cis rs797680 0.822 rs1572343 chr1:93616202 T/C cg17826107 chr1:92977322 EVI5 -0.24 -5.21 -0.42 7.63e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9393777 0.778 rs74689501 chr6:26887821 G/A cg16898833 chr6:26189333 HIST1H4D 1.13 5.55 0.45 1.65e-7 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.859 rs11657004 chr17:41442751 A/G cg23758822 chr17:41437982 NA 0.71 6.99 0.53 1.49e-10 Menopause (age at onset); TGCT cis rs11122272 0.735 rs2572253 chr1:231512768 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs6570726 0.846 rs446031 chr6:145885592 C/T cg05347473 chr6:146136440 FBXO30 0.48 4.5 0.37 1.57e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs853679 0.542 rs6934769 chr6:28090931 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs7666738 0.830 rs991169 chr4:98928567 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs4332037 0.539 rs55790766 chr7:2021248 C/T cg25834613 chr7:1915315 MAD1L1 -0.47 -4.51 -0.38 1.48e-5 Bipolar disorder; TGCT cis rs4851254 0.618 rs13001130 chr2:100668699 G/A cg22139774 chr2:100720529 AFF3 -0.43 -4.63 -0.38 9.26e-6 Intelligence (multi-trait analysis); TGCT cis rs13082711 0.596 rs479404 chr3:27363064 T/C cg02860705 chr3:27208620 NA 0.3 4.9 0.4 2.95e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs6570726 0.791 rs440477 chr6:145854188 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7120118 0.517 rs56168519 chr11:47317987 T/C cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.26e-7 HDL cholesterol; TGCT cis rs78456975 0.550 rs111467480 chr2:1569154 A/G cg12573674 chr2:1569213 NA -0.49 -5.35 -0.43 4.16e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7824557 0.606 rs2736264 chr8:11186639 G/C cg21775007 chr8:11205619 TDH 0.69 6.62 0.51 9.87e-10 Retinal vascular caliber; TGCT cis rs1976403 0.633 rs1780322 chr1:21823076 T/C cg17800788 chr1:21766015 NBPF3 0.25 4.61 0.38 1e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4950928 0.774 rs4950931 chr1:203164075 G/A cg17014757 chr1:203156097 CHI3L1 -0.38 -4.75 -0.39 5.55e-6 YKL-40 levels; TGCT cis rs2842992 0.789 rs4709370 chr6:160210061 A/G cg11366901 chr6:160182831 ACAT2 1.07 7.3 0.55 2.97e-11 Age-related macular degeneration (geographic atrophy); TGCT cis rs139371 0.516 rs139342 chr22:39507654 C/A cg18708252 chr22:39545030 CBX7 -0.31 -4.65 -0.39 8.52e-6 Multiple myeloma (IgH translocation);Multiple myeloma (hyperdiploidy); TGCT cis rs2464469 0.648 rs7173078 chr15:58203953 A/G cg12031962 chr15:58353849 ALDH1A2 -0.33 -4.61 -0.38 9.94e-6 Barrett's esophagus or Esophageal adenocarcinoma; TGCT cis rs68170813 0.605 rs10464620 chr7:107135653 A/G cg02696742 chr7:106810147 HBP1 0.66 5.24 0.43 6.72e-7 Coronary artery disease; TGCT cis rs2721195 0.743 rs2306386 chr8:145742879 T/C cg11211951 chr8:145729740 GPT 0.23 5.22 0.42 7.25e-7 Age at first birth; TGCT cis rs9486715 1.000 rs7752277 chr6:97065131 C/T cg18709589 chr6:96969512 KIAA0776 -0.78 -7.13 -0.54 7.19e-11 Headache; TGCT cis rs4924935 0.770 rs4924946 chr17:18846525 A/T cg26378065 chr17:18585709 ZNF286B -0.54 -5.23 -0.42 7.08e-7 Pancreatic cancer; TGCT cis rs593982 0.920 rs1151501 chr11:65484883 A/G cg08755490 chr11:65554678 OVOL1 1.33 7.99 0.58 7.81e-13 Atopic dermatitis; TGCT cis rs28595532 0.765 rs114082534 chr4:119734184 G/A cg21605333 chr4:119757512 SEC24D 1.62 7.49 0.56 1.1e-11 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs35752787 chr4:98935202 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9814567 0.964 rs9841180 chr3:134191880 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.97 -9.32 -0.64 5.68e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs9467711 0.606 rs9379899 chr6:26603015 T/A cg16898833 chr6:26189333 HIST1H4D 1.02 5.25 0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs904251 0.523 rs914348 chr6:37484729 G/A cg08126542 chr6:37504118 NA -0.42 -6.16 -0.48 9.53e-9 Cognitive performance; TGCT cis rs2816958 0.803 rs2737687 chr1:200094805 T/A cg07971716 chr1:199773294 NA 0.46 4.52 0.38 1.45e-5 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs35433756 chr4:99070555 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9527 0.615 rs7073295 chr10:104672233 A/G cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs9368481 0.761 rs4358615 chr6:26998567 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 0.46 5.31 0.43 4.82e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.687 rs6830176 chr4:99093955 G/C cg05340658 chr4:99064831 C4orf37 0.44 4.73 0.39 5.98e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1670533 0.872 rs6854793 chr4:1055768 T/C cg27284194 chr4:1044797 NA 0.68 5.88 0.47 3.56e-8 Recombination rate (females); TGCT cis rs13191362 1.000 rs34398656 chr6:162999612 G/T cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.925 rs2865952 chr4:99040305 C/T cg17366294 chr4:99064904 C4orf37 0.78 7.1 0.54 8.71e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7611238 0.560 rs6806850 chr3:195079711 A/G cg27323046 chr3:195102265 ACAP2 0.37 4.93 0.4 2.56e-6 Body mass index; TGCT cis rs79349575 0.729 rs62075824 chr17:46986679 A/G cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs11648796 0.757 rs763206 chr16:770103 C/G cg00908189 chr16:619842 PIGQ 0.7 5.72 0.46 7.69e-8 Height; TGCT cis rs208520 0.955 rs28684412 chr6:66979430 A/C cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs2066819 1.000 rs79750959 chr12:56702012 C/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs67478160 0.634 rs2368558 chr14:104230518 A/G cg26031613 chr14:104095156 KLC1 -0.63 -6.38 -0.5 3.18e-9 Schizophrenia; TGCT cis rs4689388 0.926 rs11732178 chr4:6292643 G/C cg25554036 chr4:6271136 WFS1 0.56 7.96 0.58 9.12e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12541335 0.639 rs3923439 chr8:22170079 G/A cg09517075 chr8:22133004 PIWIL2 0.25 4.91 0.4 2.8e-6 Hypertriglyceridemia; TGCT cis rs2832191 0.755 rs55671430 chr21:30492421 G/C cg24692254 chr21:30365293 RNF160 -0.92 -9.97 -0.67 1.45e-17 Dental caries; TGCT cis rs7666738 0.791 rs2081622 chr4:98927369 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 1.000 rs689647 chr15:43762196 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT trans rs12599106 0.679 rs34584967 chr16:34475725 T/G cg18110333 chr6:292329 DUSP22 -0.67 -7.4 -0.55 1.84e-11 Menopause (age at onset); TGCT cis rs7095607 0.538 rs2634706 chr10:69917590 A/C cg18986048 chr10:69913749 MYPN 0.61 5.85 0.46 4.16e-8 Lung function (FVC); TGCT cis rs7666738 0.791 rs6828752 chr4:99063382 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs6893807 1.000 rs1422192 chr5:87959023 G/A cg24804195 chr5:87968844 LOC645323 0.76 5.64 0.45 1.09e-7 Body mass index; TGCT cis rs7043114 0.525 rs6479416 chr9:95053871 G/T cg14631576 chr9:95140430 CENPP -0.28 -4.65 -0.39 8.23e-6 Height; TGCT cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg11644478 chr21:40555479 PSMG1 1.0 10.32 0.68 2.15e-18 Cognitive function; TGCT cis rs1334894 1.000 rs1334894 chr6:35615130 C/T cg24281267 chr6:35479648 TULP1 -0.43 -4.51 -0.38 1.46e-5 Coronary artery disease; TGCT cis rs8032315 1.000 rs6227 chr15:91425232 C/T cg06330618 chr15:91428456 FES 0.19 4.57 0.38 1.17e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs1372520 0.577 rs1811443 chr4:90747883 G/C cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs7833790 0.724 rs4739627 chr8:82734657 A/G cg23324259 chr8:82754387 SNX16 -0.61 -4.71 -0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs4242434 0.927 rs10099846 chr8:22534178 C/T cg21658235 chr8:22456391 C8orf58 -0.43 -4.47 -0.37 1.77e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs709400 1.000 rs861536 chr14:104167564 A/G cg26031613 chr14:104095156 KLC1 1.13 17.13 0.84 1.75e-34 Body mass index; TGCT cis rs9611565 0.921 rs5751081 chr22:41742788 A/T cg06634786 chr22:41940651 POLR3H -0.63 -6.01 -0.47 1.93e-8 Vitiligo; TGCT cis rs4689388 0.856 rs1046314 chr4:6303955 A/G cg14416269 chr4:6271139 WFS1 -0.4 -5.4 -0.44 3.25e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs995000 0.965 rs1570694 chr1:63103217 A/G cg15066888 chr1:62901829 USP1 -0.52 -4.52 -0.38 1.41e-5 Triglyceride levels; TGCT cis rs1008375 1.000 rs12507142 chr4:17656103 A/G cg10189774 chr4:17578691 LAP3 0.55 4.9 0.4 2.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2486288 0.656 rs2461705 chr15:45570241 A/G cg14582100 chr15:45693742 SPATA5L1 -0.42 -4.64 -0.38 8.63e-6 Glomerular filtration rate; TGCT cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4713118 0.513 rs149878 chr6:27878738 T/G cg10876282 chr6:28092338 ZSCAN16 0.48 4.52 0.38 1.45e-5 Parkinson's disease; TGCT cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs921968 0.678 rs500422 chr2:219432995 C/A cg02176678 chr2:219576539 TTLL4 0.36 5.11 0.42 1.2e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs76878669 0.561 rs12420203 chr11:66163794 T/C cg18002602 chr11:66138449 SLC29A2 0.53 6.57 0.51 1.22e-9 Educational attainment (years of education); TGCT cis rs7829975 0.606 rs10112585 chr8:8795030 A/T cg15556689 chr8:8085844 FLJ10661 -0.69 -6.25 -0.49 5.93e-9 Mood instability; TGCT cis rs1113500 0.575 rs1781070 chr1:108569698 A/G cg22161131 chr1:109420278 GPSM2 -0.58 -5.57 -0.45 1.54e-7 Growth-regulated protein alpha levels; TGCT cis rs7552404 0.961 rs448710 chr1:76116554 T/C cg03433033 chr1:76189801 ACADM -0.84 -10.12 -0.67 6.47e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1008375 1.000 rs10939738 chr4:17604295 G/C cg10189774 chr4:17578691 LAP3 0.57 4.9 0.4 2.93e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7613875 0.600 rs7061 chr3:50114515 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.82 -8.52 -0.61 4.53e-14 Body mass index; TGCT cis rs7824557 0.583 rs2263511 chr8:11233318 A/C cg21775007 chr8:11205619 TDH -0.66 -6.81 -0.52 3.79e-10 Retinal vascular caliber; TGCT cis rs1395 0.744 rs3739092 chr2:27462076 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.4 0.65 3.52e-16 Blood metabolite levels; TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs425277 1.000 rs425277 chr1:2069172 C/T cg24578937 chr1:2090814 PRKCZ 0.31 7.13 0.54 7.33e-11 Height; TGCT cis rs4919669 0.668 rs10883735 chr10:104308446 C/T cg05855489 chr10:104503620 C10orf26 0.71 4.57 0.38 1.18e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs10883723 0.810 rs7090276 chr10:104281239 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1461503 0.966 rs4936764 chr11:122844492 G/A cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs877282 1.000 rs2004479 chr10:770854 G/A cg17470449 chr10:769945 NA 0.32 4.93 0.4 2.56e-6 Uric acid levels; TGCT cis rs924607 0.931 rs1709556 chr5:637058 A/G cg18765565 chr5:669397 TPPP 0.58 6.07 0.48 1.45e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs10464366 0.560 rs12672089 chr7:39132816 G/A cg15212455 chr7:39170539 POU6F2 0.24 5.54 0.45 1.72e-7 IgG glycosylation; TGCT cis rs13242816 1.000 rs35184471 chr7:116133246 G/A cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT trans rs916888 0.821 rs199507 chr17:44858855 A/G cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs782590 0.559 rs12617719 chr2:55915826 G/C cg03859395 chr2:55845619 SMEK2 -0.72 -7.85 -0.58 1.67e-12 Metabolic syndrome; TGCT cis rs2013441 1.000 rs12451216 chr17:20025840 C/A cg18979559 chr17:20280153 CCDC144C 0.46 4.8 0.4 4.42e-6 Obesity-related traits; TGCT cis rs10992471 0.603 rs10761163 chr9:95313287 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.68 -0.45 9.01e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4906332 1.000 rs35862113 chr14:103857229 G/T cg26031613 chr14:104095156 KLC1 -0.52 -4.77 -0.39 5.12e-6 Coronary artery disease; TGCT cis rs11754661 1.000 rs11755145 chr6:151207249 G/A cg11579907 chr6:151412213 MTHFD1L 0.54 4.91 0.4 2.83e-6 Alzheimer's disease (late onset); TGCT cis rs2239547 0.657 rs7638524 chr3:52874861 G/A cg11645453 chr3:52864694 ITIH4 0.35 5.88 0.47 3.57e-8 Schizophrenia; TGCT cis rs9549260 0.522 rs4245401 chr13:41277736 G/T cg21288729 chr13:41239152 FOXO1 0.93 9.23 0.64 8.96e-16 Red blood cell count; TGCT cis rs79057730 0.599 rs9458 chr7:825494 A/G cg06242242 chr7:766104 PRKAR1B;HEATR2 -0.64 -5.43 -0.44 2.84e-7 Initial pursuit acceleration; TGCT cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg19318889 chr4:1322082 MAEA 0.28 6.72 0.52 6.01e-10 Longevity; TGCT cis rs1775715 0.966 rs1755066 chr10:32309160 C/G cg14930904 chr10:32216787 ARHGAP12 -0.5 -4.63 -0.38 8.96e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs16866061 0.962 rs72972361 chr2:225341550 G/A cg12698349 chr2:225449008 CUL3 0.96 9.45 0.65 2.69e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs9372498 0.505 rs9489462 chr6:118927855 C/T cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.95 -7.12 -0.54 7.49e-11 Gut microbiome composition (summer); TGCT cis rs1903068 0.597 rs10013070 chr4:55997201 A/G cg16572876 chr4:56024045 NA 0.43 4.6 0.38 1.04e-5 Endometriosis; TGCT cis rs6570726 0.791 rs6915094 chr6:145883540 C/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7659604 1.000 rs28618203 chr4:122663935 T/C cg19748678 chr4:122722346 EXOSC9 0.57 5.43 0.44 2.83e-7 Type 2 diabetes; TGCT cis rs9467773 0.933 rs2024970 chr6:26497520 T/A cg15659132 chr6:26577336 NA 0.63 6.72 0.52 5.88e-10 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.577 rs7816329 chr8:8543843 G/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.17 -0.42 9.06e-7 Mood instability; TGCT cis rs514406 0.825 rs28817407 chr1:53226116 G/A cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.42e-13 Monocyte count; TGCT cis rs4919044 0.808 rs9420608 chr10:94800903 C/G cg05127821 chr10:94822908 CYP26C1 0.74 4.83 0.4 3.95e-6 Coronary artery disease; TGCT cis rs1532993 0.518 rs11097569 chr4:98602671 C/A cg05340658 chr4:99064831 C4orf37 -0.38 -4.49 -0.37 1.58e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9419702 0.568 rs11156445 chr10:133542301 T/C cg23460707 chr10:133558971 NA 0.42 4.83 0.4 4e-6 Survival in rectal cancer; TGCT cis rs10804591 0.832 rs1075469 chr3:129340295 C/T cg07730360 chr3:128845626 NA 0.23 4.63 0.38 9.25e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7647973 0.771 rs9865051 chr3:49166069 C/T cg07636037 chr3:49044803 WDR6 0.81 6.32 0.49 4.31e-9 Menarche (age at onset); TGCT cis rs10992471 0.627 rs10820980 chr9:95253342 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.47 -0.44 2.4e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4523957 0.651 rs9898819 chr17:2076352 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2276314 1.000 rs2298716 chr18:33552598 C/T cg19628046 chr18:33552617 C18orf21 0.53 4.5 0.37 1.57e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs2832191 0.755 rs55671430 chr21:30492421 G/C cg08807101 chr21:30365312 RNF160 -0.62 -5.74 -0.46 6.74e-8 Dental caries; TGCT cis rs9811920 0.809 rs793476 chr3:99541747 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.03 0.41 1.7e-6 Axial length; TGCT cis rs4713118 0.513 rs149954 chr6:28035246 G/A cg10876282 chr6:28092338 ZSCAN16 0.49 4.54 0.38 1.3e-5 Parkinson's disease; TGCT cis rs12210905 1.000 rs72843611 chr6:27131382 C/T cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs12900413 0.603 rs11629982 chr15:90300272 G/A cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs10510102 0.872 rs74318512 chr10:123700980 G/T cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg08048268 chr3:133502702 NA -0.53 -7.17 -0.54 5.89e-11 Iron status biomarkers; TGCT cis rs881375 0.967 rs2416805 chr9:123676482 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.78 0.39 4.84e-6 Rheumatoid arthritis; TGCT cis rs2354432 0.556 rs2353977 chr1:146839637 G/T cg25205988 chr1:146714368 CHD1L 1.33 5.89 0.47 3.34e-8 Mitochondrial DNA levels; TGCT cis rs617219 0.726 rs955897 chr5:78431486 A/C cg23514016 chr5:78407564 BHMT 0.33 4.93 0.4 2.58e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs67311347 0.824 rs59922539 chr3:40337110 G/A cg13683864 chr3:40499215 RPL14 -0.9 -8.68 -0.61 1.87e-14 Renal cell carcinoma; TGCT trans rs1814175 0.817 rs11493756 chr11:50017885 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs7044106 0.762 rs13291660 chr9:123392748 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.58 0.51 1.19e-9 Hip circumference adjusted for BMI; TGCT cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg04944784 chr2:26401820 FAM59B -0.78 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT cis rs12765878 1.000 rs2902639 chr10:105658588 G/C cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs17594362 0.573 rs79859984 chr13:42147427 G/A cg09909069 chr13:41860793 NA -0.36 -4.45 -0.37 1.86e-5 Multiple sclerosis; TGCT cis rs9322193 0.923 rs10872650 chr6:150082095 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs7226408 0.948 rs11665642 chr18:34387438 A/C cg06757138 chr18:34340585 FHOD3 -0.25 -4.57 -0.38 1.17e-5 Obesity-related traits; TGCT cis rs6545883 0.929 rs3732171 chr2:61749690 C/T cg15711740 chr2:61764176 XPO1 -0.59 -5.44 -0.44 2.76e-7 Tuberculosis; TGCT trans rs9951602 0.512 rs77157626 chr18:76644771 C/T cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs896854 0.548 rs574183 chr8:95973816 A/G cg23172400 chr8:95962367 TP53INP1 0.37 5.94 0.47 2.74e-8 Type 2 diabetes; TGCT cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs727563 0.635 rs713988 chr22:42159072 A/G cg06481639 chr22:41940642 POLR3H 0.69 6.02 0.48 1.83e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9952991 0.528 rs612058 chr18:12850211 T/C cg23544223 chr18:12777786 NA 0.55 4.88 0.4 3.22e-6 Inflammatory skin disease; TGCT cis rs9902453 0.874 rs7220004 chr17:28369548 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs9640161 0.789 rs3735172 chr7:150028958 C/T cg10018233 chr7:150070692 REPIN1 -0.31 -4.62 -0.38 9.33e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs10465746 1.000 rs10465746 chr1:84387632 T/G cg10977910 chr1:84465055 TTLL7 0.67 6.63 0.51 9.19e-10 Obesity-related traits; TGCT cis rs7937682 0.889 rs578022 chr11:111490552 G/T cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs6089829 0.962 rs6011544 chr20:61658782 T/C cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs12477438 0.953 rs3851334 chr2:99794704 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.46 -0.61 6.14e-14 Chronic sinus infection; TGCT cis rs2074038 1.000 rs2074038 chr11:44087989 G/T cg20240860 chr11:44087423 ACCS -0.49 -4.85 -0.4 3.63e-6 IgA nephropathy; TGCT cis rs9368481 0.761 rs3931464 chr6:26939856 C/A cg18867708 chr6:26865862 GUSBL1 0.36 4.67 0.39 7.78e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs61884328 0.777 rs61897784 chr11:47154514 A/G cg13308137 chr11:47528955 CUGBP1 0.38 4.47 0.37 1.76e-5 Total body bone mineral density (age over 60); TGCT cis rs13401104 0.587 rs7569760 chr2:237145713 A/C cg26422059 chr2:237146110 ASB18 0.57 4.56 0.38 1.19e-5 Educational attainment; TGCT cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs9291683 0.551 rs2240720 chr4:10020480 C/T cg11266682 chr4:10021025 SLC2A9 0.69 10.28 0.68 2.66e-18 Bone mineral density; TGCT cis rs1552244 0.626 rs2886396 chr3:10037670 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs16939607 0.908 rs16939604 chr8:79005681 T/A cg21244580 chr8:79934476 NA 0.48 4.77 0.39 5e-6 White blood cell count; TGCT cis rs227917 1.000 rs7803526 chr7:23686084 G/A cg12601843 chr7:23510954 IGF2BP3 0.63 4.87 0.4 3.28e-6 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg11890956 chr21:40555474 PSMG1 -0.8 -7.51 -0.56 9.89e-12 Cognitive function; TGCT cis rs10510102 0.810 rs34738294 chr10:123710872 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs5769765 0.862 rs9616384 chr22:50313082 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs644148 0.867 rs2571060 chr19:44971647 C/G cg15540054 chr19:45004280 ZNF180 -0.59 -5.21 -0.42 7.8e-7 Personality dimensions; TGCT cis rs780096 0.565 rs780104 chr2:27677691 G/A cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT cis rs67311347 1.000 rs7636719 chr3:40432084 C/T cg13683864 chr3:40499215 RPL14 -1.05 -11.13 -0.71 2.2e-20 Renal cell carcinoma; TGCT cis rs9527 0.544 rs3781280 chr10:104863843 T/G cg04362960 chr10:104952993 NT5C2 0.68 5.83 0.46 4.43e-8 Arsenic metabolism; TGCT cis rs9581857 0.547 rs9581882 chr13:28110682 C/G cg22138327 chr13:27999177 GTF3A 0.7 4.53 0.38 1.36e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs4906332 0.811 rs2756138 chr14:103996733 C/G cg26031613 chr14:104095156 KLC1 0.58 4.69 0.39 7.07e-6 Coronary artery disease; TGCT cis rs763121 0.962 rs5757130 chr22:38937794 G/A cg06022373 chr22:39101656 GTPBP1 0.74 7.38 0.55 2.04e-11 Menopause (age at onset); TGCT cis rs7824557 0.564 rs7834572 chr8:11236685 C/T cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT trans rs12655019 0.920 rs75167082 chr5:56211404 T/C cg25190722 chr1:3801660 DFFB 0.62 7.17 0.54 5.87e-11 Breast cancer (early onset); TGCT cis rs6754311 0.509 rs12616520 chr2:136516748 A/T cg07169764 chr2:136633963 MCM6 -0.71 -6.37 -0.5 3.33e-9 Mosquito bite size; TGCT cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.44 0.56 1.45e-11 Platelet count; TGCT cis rs600231 0.665 rs1616810 chr11:65220105 A/G cg11802864 chr11:65308245 LTBP3 0.46 4.56 0.38 1.22e-5 Bone mineral density; TGCT cis rs7119 0.717 rs12901100 chr15:77815558 T/A cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs12360000 0.864 rs12767731 chr10:1907712 T/C cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs116095464 0.619 rs2303741 chr5:218356 T/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs910187 0.641 rs3818011 chr20:45816566 A/G cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs2688608 0.592 rs2306328 chr10:75579510 C/T cg04320760 chr10:75533139 FUT11 -0.37 -5.72 -0.46 7.3900000000000007e-08 Inflammatory bowel disease; TGCT trans rs1814175 0.626 rs1722008 chr11:49897676 A/T cg15704280 chr7:45808275 SEPT13 -0.7 -7.79 -0.57 2.32e-12 Height; TGCT cis rs7666738 0.753 rs13137152 chr4:98938044 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs4149178 0.722 rs10948072 chr6:43307861 G/A cg07522644 chr6:43142093 SRF 0.63 4.5 0.37 1.52e-5 Urate levels; TGCT cis rs2862064 1.000 rs6896499 chr5:156431325 A/G cg12943317 chr5:156479607 HAVCR1 -0.45 -5.92 -0.47 2.96e-8 Platelet count; TGCT cis rs778371 0.723 rs6739794 chr2:233576165 G/A cg08000102 chr2:233561755 GIGYF2 0.75 8.97 0.63 3.75e-15 Schizophrenia; TGCT cis rs9910055 0.550 rs113844752 chr17:42297631 C/A cg13607699 chr17:42295918 UBTF 1.14 12.78 0.75 2.21e-24 Total body bone mineral density; TGCT cis rs17376456 0.569 rs2045019 chr5:93201971 C/T cg21475434 chr5:93447410 FAM172A -0.68 -5.22 -0.42 7.16e-7 Diabetic retinopathy; TGCT cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs7829975 0.606 rs891570 chr8:8794454 G/A cg15556689 chr8:8085844 FLJ10661 -0.7 -6.26 -0.49 5.66e-9 Mood instability; TGCT cis rs2439831 0.850 rs8032649 chr15:44134922 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.85 -6.18 -0.48 8.67e-9 Lung cancer in ever smokers; TGCT cis rs7572733 0.515 rs1401096 chr2:198823828 A/G cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs17221829 0.965 rs72952901 chr11:89457303 A/G cg02982614 chr11:89391479 FOLH1B -0.27 -4.88 -0.4 3.23e-6 Anxiety in major depressive disorder; TGCT cis rs4727027 0.840 rs12670633 chr7:148796707 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.68 0.39 7.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs4332037 0.754 rs62436669 chr7:1926636 G/A cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT cis rs860554 0.705 rs832165 chr1:201255517 G/C cg01022117 chr1:201258280 PKP1 0.34 5.05 0.41 1.52e-6 Panic disorder; TGCT trans rs10022799 0.725 rs7683098 chr4:168137979 A/G cg08507725 chr4:8239220 SH3TC1 0.42 7.37 0.55 2.15e-11 Cognitive function; TGCT cis rs2197308 0.765 rs11182481 chr12:37926019 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.79 0.57 2.32e-12 Morning vs. evening chronotype; TGCT cis rs2072499 0.932 rs3001790 chr1:156165290 T/G cg24450063 chr1:156163899 SLC25A44 1.17 16.76 0.83 1.19e-33 Testicular germ cell tumor; TGCT cis rs9638182 0.725 rs35173225 chr7:73001021 C/T cg14087351 chr7:73037990 MLXIPL -0.69 -5.34 -0.43 4.19e-7 Triglycerides; TGCT cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg25151919 chr3:44754333 ZNF502 0.47 5.45 0.44 2.56e-7 Depressive symptoms; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg23131131 chr22:24373011 LOC391322 -0.82 -8.88 -0.62 6.37e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6570726 0.764 rs451108 chr6:145844309 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.84 0.4 3.75e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs950169 0.800 rs4842847 chr15:84931199 G/A cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs2370759 1.000 rs7910776 chr10:32639093 C/T cg01819863 chr10:32635814 EPC1 0.93 5.54 0.45 1.75e-7 Sexual dysfunction (female); TGCT cis rs7659604 0.539 rs1507995 chr4:122748308 G/A cg06713675 chr4:122721982 EXOSC9 -0.67 -8.88 -0.62 6.44e-15 Type 2 diabetes; TGCT cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.62 -6.91 -0.53 2.28e-10 Blood metabolite levels; TGCT cis rs8103278 1.000 rs8108590 chr19:46301620 A/G cg14061069 chr19:46274453 DMPK -0.41 -5.78 -0.46 5.56e-8 Coronary artery disease; TGCT cis rs4925386 1.000 rs4925386 chr20:60921044 C/T cg06026331 chr20:60912101 LAMA5 0.29 5.47 0.44 2.33e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs4566357 0.615 rs10184991 chr2:227916533 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs36051895 0.664 rs10121077 chr9:5098411 G/A cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.16e-20 Pediatric autoimmune diseases; TGCT cis rs28595532 0.920 rs114653217 chr4:119769216 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs7412746 0.646 rs1972060 chr1:150937594 T/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.7 0.39 6.76e-6 Melanoma; TGCT cis rs1943345 0.731 rs498292 chr11:82903283 C/T cg07047830 chr11:82868014 PCF11 0.52 5.27 0.43 5.97e-7 Obesity-related traits; TGCT cis rs6461049 0.638 rs3778994 chr7:2175855 G/T cg22963979 chr7:1858916 MAD1L1 -0.41 -6.66 -0.51 7.83e-10 Schizophrenia; TGCT cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg08219700 chr8:58056026 NA 0.3 4.6 0.38 1.02e-5 Developmental language disorder (linguistic errors); TGCT cis rs116095464 0.558 rs56342538 chr5:225796 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.97 0.47 2.35e-8 Schizophrenia; TGCT cis rs9325144 0.560 rs10876005 chr12:39126149 C/G cg26384229 chr12:38710491 ALG10B -0.63 -5.87 -0.47 3.66e-8 Morning vs. evening chronotype; TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg02353165 chr6:42928485 GNMT 0.95 9.59 0.65 1.26e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7336332 0.598 rs12018313 chr13:28012266 C/A cg22138327 chr13:27999177 GTF3A 0.81 6.35 0.5 3.66e-9 Weight; TGCT cis rs8179 0.553 rs42038 chr7:92243719 A/G cg15732164 chr7:92237376 CDK6 0.24 4.46 0.37 1.78e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs79349575 0.783 rs4793992 chr17:47008207 A/G cg07967210 chr17:47022446 SNF8 0.42 5.86 0.47 3.94e-8 Type 2 diabetes; TGCT cis rs11148252 0.508 rs11148260 chr13:53162643 A/C cg00495681 chr13:53174319 NA 0.6 5.83 0.46 4.59e-8 Lewy body disease; TGCT cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.63 0.38 8.9e-6 Obesity-related traits; TGCT cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg20203395 chr5:56204925 C5orf35 -0.59 -4.94 -0.41 2.52e-6 Initial pursuit acceleration; TGCT cis rs6835098 0.961 rs11737748 chr4:174130503 T/C cg08422745 chr4:174089978 GALNT7 0.9 10.24 0.68 3.33e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs1056107 0.931 rs10817295 chr9:114997590 T/A cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs17270561 1.000 rs79867288 chr6:25828416 A/G cg15022984 chr6:26056706 HIST1H1C -0.73 -4.6 -0.38 1.02e-5 Iron status biomarkers; TGCT cis rs9902453 0.899 rs1979572 chr17:28511978 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg05573699 chr3:52720067 GNL3;PBRM1 0.51 4.82 0.4 4.07e-6 Bipolar disorder; TGCT cis rs916888 0.821 rs199514 chr17:44856881 G/A cg01570182 chr17:44337453 NA -1.02 -9.18 -0.64 1.24e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9467711 0.606 rs9366653 chr6:26354247 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7258465 1.000 rs271624 chr19:18627953 A/G cg06462663 chr19:18546047 ISYNA1 0.21 4.98 0.41 2.12e-6 Breast cancer; TGCT cis rs6663390 0.831 rs3754172 chr1:208086878 G/T cg03990033 chr1:208084030 CD34 0.55 5.55 0.45 1.67e-7 Facial morphology (factor 18); TGCT cis rs5769707 0.749 rs8137251 chr22:50036669 G/A cg05373962 chr22:49881684 NA -0.33 -6.28 -0.49 5.24e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1670533 1.000 rs4690212 chr4:1054898 T/C cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs17433780 0.504 rs7525985 chr1:89460948 C/T cg09516651 chr1:89888402 LOC400759 0.26 5.39 0.44 3.35e-7 Carotid intima media thickness; TGCT trans rs916888 0.779 rs430685 chr17:44859148 T/C cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7192750 0.586 rs8054111 chr16:71990651 A/G cg06353428 chr16:71660113 MARVELD3 0.71 6.25 0.49 5.94e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs3008870 1.000 rs2985811 chr1:67377722 G/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.08 0.74 1.11e-22 Lymphocyte percentage of white cells; TGCT cis rs9560113 1.000 rs9555805 chr13:112179765 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs796364 0.806 rs12619136 chr2:200910347 C/A cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs2046867 0.862 rs2322612 chr3:72830058 A/G cg25664220 chr3:72788482 NA -0.57 -7.14 -0.54 7.09e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.84 0.46 4.39e-8 Height; TGCT cis rs6922617 0.786 rs11961196 chr6:41344962 A/C cg07798131 chr6:41471673 NA 0.97 4.79 0.4 4.65e-6 Alzheimer's disease biomarkers; TGCT cis rs7829975 0.511 rs2921028 chr8:8340477 T/C cg06636001 chr8:8085503 FLJ10661 0.63 5.86 0.47 3.86e-8 Mood instability; TGCT cis rs9788682 1.000 rs7181447 chr15:78814567 A/G cg24631222 chr15:78858424 CHRNA5 0.89 7.68 0.57 4.22e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs4689388 0.856 rs3200 chr4:6304878 C/T cg25554036 chr4:6271136 WFS1 0.56 7.87 0.58 1.51e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9926296 0.712 rs258330 chr16:89729574 T/G cg01097406 chr16:89675127 NA 0.34 5.88 0.47 3.54e-8 Vitiligo; TGCT cis rs2371030 1.000 rs12473296 chr2:211583281 A/C cg18417063 chr2:211583084 NA -0.31 -4.45 -0.37 1.91e-5 Non-small cell lung cancer; TGCT cis rs7552404 1.000 rs4949674 chr1:76213715 C/A cg22875332 chr1:76189707 ACADM 0.76 9.2 0.64 1.1e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10464366 0.544 rs12668821 chr7:39167846 T/A cg18850127 chr7:39170497 POU6F2 0.33 7.16 0.54 6.13e-11 IgG glycosylation; TGCT cis rs7818688 0.697 rs76215523 chr8:95987015 T/C cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs797680 0.927 rs797675 chr1:93674226 A/T cg17826107 chr1:92977322 EVI5 -0.24 -5.3 -0.43 5.16e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs57590327 0.555 rs3755713 chr3:81811224 A/G cg07356753 chr3:81810745 GBE1 -0.73 -6.73 -0.52 5.57e-10 Extraversion; TGCT cis rs7615952 0.932 rs6438948 chr3:125650045 A/T cg05084668 chr3:125655381 ALG1L 0.73 6.26 0.49 5.78e-9 Blood pressure (smoking interaction); TGCT cis rs2439831 0.867 rs28461955 chr15:43661459 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs7267979 0.844 rs35735333 chr20:25337205 T/G cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9926296 0.533 rs7190823 chr16:89866043 A/G cg26513180 chr16:89883248 FANCA 1.04 14.31 0.79 4.97e-28 Vitiligo; TGCT cis rs2354432 0.607 rs6593751 chr1:146726023 A/G cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs734999 0.588 rs6668149 chr1:2558308 A/C cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg27588902 chr6:42928151 GNMT 0.44 5.23 0.43 7e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7267979 1.000 rs7018 chr20:25278261 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854765 0.505 rs4506969 chr17:17899839 A/G cg04398451 chr17:18023971 MYO15A -0.31 -4.87 -0.4 3.26e-6 Total body bone mineral density; TGCT cis rs62283056 0.512 rs10028875 chr4:6283460 C/T cg25554036 chr4:6271136 WFS1 0.53 6.86 0.52 2.94e-10 Cisplatin-induced ototoxicity; TGCT cis rs1218582 0.740 rs1977879 chr1:154879743 G/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs854765 0.547 rs9897761 chr17:17912011 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.4 0.6 8.61e-14 Total body bone mineral density; TGCT cis rs611744 0.507 rs1579924 chr8:109324884 G/T cg21045802 chr8:109455806 TTC35 0.75 7.56 0.56 7.59e-12 Dupuytren's disease; TGCT cis rs9921338 0.961 rs7191093 chr16:11442279 A/G cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.37e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs12765878 1.000 rs11191847 chr10:105650626 G/C cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9858542 0.537 rs2304442 chr3:49322027 A/T cg00383909 chr3:49044727 WDR6 -0.65 -4.49 -0.37 1.6e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7727544 0.513 rs10065787 chr5:131436486 G/T cg24060327 chr5:131705240 SLC22A5 -0.48 -4.8 -0.4 4.57e-6 Blood metabolite levels; TGCT cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs11098499 0.908 rs7695996 chr4:120322033 C/T cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.25e-9 Corneal astigmatism; TGCT cis rs3796352 0.881 rs13100714 chr3:53074824 T/G cg27565382 chr3:53032988 SFMBT1 0.43 4.62 0.38 9.64e-6 Immune reponse to smallpox (secreted IL-2); TGCT trans rs1005277 0.579 rs176880 chr10:38401417 C/G cg17830980 chr10:43048298 ZNF37B 0.87 11.26 0.71 1.1e-20 Extrinsic epigenetic age acceleration; TGCT cis rs7917772 0.546 rs10883743 chr10:104338389 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9952991 0.883 rs2847293 chr18:12782448 A/T cg23544223 chr18:12777786 NA 0.63 6.02 0.48 1.85e-8 Inflammatory skin disease; TGCT cis rs4891159 0.790 rs72975930 chr18:74144645 G/A cg24786174 chr18:74118243 ZNF516 -0.53 -6.98 -0.53 1.6e-10 Longevity; TGCT cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg17971929 chr21:40555470 PSMG1 -0.51 -4.47 -0.37 1.74e-5 Menarche (age at onset); TGCT cis rs9467773 1.000 rs6456733 chr6:26566804 C/T cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs11097607 chr4:99011640 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9660992 0.686 rs1668870 chr1:205239031 C/G cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.97 -7.19 -0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs3027009 0.881 rs12042284 chr1:159132649 A/C cg24432768 chr1:158149974 CD1D -0.48 -4.76 -0.39 5.25e-6 Lean body mass and age at menarche (combined); TGCT cis rs523522 0.962 rs3759394 chr12:120933173 C/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs2549003 1.000 rs2548999 chr5:131831058 G/T cg02551604 chr5:131831745 NA 0.9 12.24 0.74 4.6e-23 Asthma (sex interaction); TGCT cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg05738196 chr6:26577821 NA 0.88 10.62 0.69 3.92e-19 Intelligence (multi-trait analysis); TGCT cis rs2188554 0.771 rs213951 chr7:117202434 A/G cg08576598 chr7:116962626 WNT2 -0.36 -4.56 -0.38 1.23e-5 Esophageal adenocarcinoma; TGCT cis rs10832963 1.000 rs7943121 chr11:18656062 G/C cg20219074 chr11:18656078 SPTY2D1 0.98 9.9 0.66 2.19e-17 Breast cancer; TGCT cis rs61884328 0.733 rs57012996 chr11:47194924 T/G cg13308137 chr11:47528955 CUGBP1 0.38 4.48 0.37 1.65e-5 Total body bone mineral density (age over 60); TGCT cis rs2404602 1.000 rs2404741 chr15:76851735 C/T cg22467129 chr15:76604101 ETFA -0.58 -6.68 -0.51 7.09e-10 Blood metabolite levels; TGCT trans rs62103177 0.810 rs62103189 chr18:77627815 G/A cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg07332563 chr6:291687 DUSP22 -0.76 -7.73 -0.57 3.11e-12 Menopause (age at onset); TGCT cis rs10484885 0.824 rs72919954 chr6:90515665 T/A cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.51 -0.38 1.46e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6988636 1.000 rs28670850 chr8:124189125 A/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs8033133 0.602 rs3803326 chr15:25328715 A/G cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.25 -4.89 -0.4 3.04e-6 Blood osmolality (transformed sodium); TGCT cis rs1218582 0.741 rs11264283 chr1:154869552 A/G cg24250549 chr1:154909240 PMVK 0.65 6.41 0.5 2.78e-9 Prostate cancer; TGCT cis rs7394190 0.748 rs11000764 chr10:75506864 A/G cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.48e-6 Incident atrial fibrillation; TGCT cis rs9534288 0.830 rs2404963 chr13:46632836 C/T cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Intelligence (multi-trait analysis); TGCT cis rs514406 0.505 rs431459 chr1:53183230 T/G cg08859206 chr1:53392774 SCP2 -0.35 -5.18 -0.42 8.58e-7 Monocyte count; TGCT cis rs10057188 0.903 rs10064912 chr5:77909527 C/G cg21097283 chr5:76934461 OTP 0.47 4.49 0.37 1.62e-5 Pulse pressure; TGCT cis rs4517514 0.509 rs10765252 chr11:89875664 C/T cg14505434 chr11:89522851 NA 0.45 4.45 0.37 1.87e-5 Trans fatty acid levels; TGCT cis rs7432375 0.901 rs6802702 chr3:136489563 G/A cg12473912 chr3:136751656 NA -0.36 -5.11 -0.42 1.17e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9926296 0.656 rs2376882 chr16:89827002 T/C cg04287289 chr16:89883240 FANCA 0.64 6.51 0.5 1.69e-9 Vitiligo; TGCT cis rs74233809 1.000 rs12221193 chr10:104665267 A/C cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs6754311 0.544 rs11693502 chr2:136808949 C/T cg07169764 chr2:136633963 MCM6 -0.57 -5.55 -0.45 1.65e-7 Mosquito bite size; TGCT cis rs2404602 0.684 rs10851888 chr15:76902506 C/T cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs2997447 0.637 rs2000403 chr1:26410161 A/G cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs651907 0.737 rs9844218 chr3:101584983 C/T cg11279151 chr3:101281821 RG9MTD1 0.25 5.18 0.42 8.81e-7 Colorectal cancer; TGCT cis rs5750830 0.594 rs9611166 chr22:39775268 T/C cg05872129 chr22:39784769 NA -0.84 -8.83 -0.62 8.39e-15 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.583 rs11078406 chr17:17840823 G/T cg09796270 chr17:17721594 SREBF1 0.24 4.78 0.39 4.92e-6 Total body bone mineral density; TGCT cis rs7402982 0.934 rs8027457 chr15:99204101 A/G cg03437748 chr15:99193247 IGF1R 0.55 6.05 0.48 1.57e-8 Birth weight; TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -5.02 -0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs6714710 0.603 rs11679828 chr2:98517626 G/A cg26665480 chr2:98280029 ACTR1B 0.64 6.06 0.48 1.48e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2204008 0.777 rs8189597 chr12:38307739 G/C cg13010199 chr12:38710504 ALG10B -0.6 -4.7 -0.39 6.73e-6 Bladder cancer; TGCT cis rs875971 0.862 rs778680 chr7:65840414 G/A cg11764359 chr7:65958608 NA 0.58 5.31 0.43 4.91e-7 Aortic root size; TGCT cis rs854765 0.647 rs854818 chr17:18022039 A/C cg04398451 chr17:18023971 MYO15A -0.39 -6.81 -0.52 3.78e-10 Total body bone mineral density; TGCT cis rs7772486 0.790 rs9403749 chr6:146162239 A/G cg13319975 chr6:146136371 FBXO30 -0.53 -4.77 -0.39 5.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4713118 0.868 rs760587 chr6:27740300 C/A cg20933634 chr6:27740509 NA 0.35 4.72 0.39 6.38e-6 Parkinson's disease; TGCT cis rs9325144 0.647 rs12229104 chr12:39110811 T/A cg26384229 chr12:38710491 ALG10B -0.57 -5.3 -0.43 5.16e-7 Morning vs. evening chronotype; TGCT cis rs2404602 0.692 rs3110382 chr15:77148688 G/A cg22467129 chr15:76604101 ETFA 0.47 5.4 0.44 3.26e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs9998803 chr4:99002519 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7552404 0.556 rs12124417 chr1:76353294 T/C cg10523679 chr1:76189770 ACADM 0.74 6.8 0.52 4.01e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7020830 0.898 rs12000309 chr9:37230844 G/A cg14294708 chr9:37120828 ZCCHC7 1.26 18.08 0.85 1.49e-36 Schizophrenia; TGCT cis rs6840360 0.806 rs11932383 chr4:152716136 T/C cg22705602 chr4:152727874 NA 0.25 4.61 0.38 9.95e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs10028505 chr4:98962310 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4746818 1.000 rs906217 chr10:70954661 T/C cg11621586 chr10:70884670 VPS26A 1.1 7.75 0.57 2.8e-12 Left atrial antero-posterior diameter; TGCT cis rs11105298 0.891 rs10858900 chr12:89925081 C/A cg00757033 chr12:89920650 WDR51B 0.31 4.92 0.4 2.7e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs478304 0.654 rs10896034 chr11:65460783 T/A cg27068330 chr11:65405492 SIPA1 -0.99 -11.32 -0.71 7.67e-21 Acne (severe); TGCT cis rs9362426 1.000 rs414013 chr6:88085866 T/G cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.19 0.42 8.5e-7 Depressive episodes in bipolar disorder; TGCT cis rs4443100 0.670 rs9612225 chr22:23406619 G/A cg14186256 chr22:23484241 RTDR1 0.57 4.47 0.37 1.76e-5 Serum parathyroid hormone levels; TGCT cis rs514406 0.861 rs1749907 chr1:53259658 C/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs116095464 0.558 rs62344300 chr5:246336 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.68 4.49 0.37 1.59e-5 Breast cancer; TGCT cis rs938554 0.513 rs3733588 chr4:9997303 A/G cg11266682 chr4:10021025 SLC2A9 -0.57 -5.99 -0.47 2.07e-8 Blood metabolite levels; TGCT cis rs2836974 0.897 rs35123057 chr21:40711689 C/T cg06238570 chr21:40685208 BRWD1 0.67 5.95 0.47 2.5e-8 Cognitive function; TGCT cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg18252515 chr7:66147081 NA -1.06 -6.34 -0.49 3.94e-9 Diabetic kidney disease; TGCT cis rs4889855 0.530 rs4890052 chr17:78564245 G/T cg16591659 chr17:78472290 NA 0.28 4.46 0.37 1.84e-5 Fractional excretion of uric acid; TGCT cis rs7412746 0.611 rs4509581 chr1:150774465 A/G cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg05665937 chr4:1216051 CTBP1 0.25 4.75 0.39 5.64e-6 Obesity-related traits; TGCT cis rs7085104 0.632 rs4290163 chr10:104610926 G/T cg15744005 chr10:104629667 AS3MT -0.46 -5.87 -0.47 3.68e-8 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7914558 1.000 rs4917996 chr10:104925829 A/C cg15744005 chr10:104629667 AS3MT -0.39 -4.75 -0.39 5.53e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4808199 0.948 rs2301668 chr19:19452249 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.33 0.43 4.49e-7 Nonalcoholic fatty liver disease; TGCT cis rs9372498 0.505 rs72956993 chr6:118949708 A/T cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs7246657 0.882 rs28623164 chr19:37913453 G/A cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs709400 0.633 rs10141433 chr14:103962559 A/G cg26031613 chr14:104095156 KLC1 0.84 9.5 0.65 2.08e-16 Body mass index; TGCT cis rs17030434 0.728 rs2124641 chr4:154645810 T/C cg14289246 chr4:154710475 SFRP2 0.8 5.87 0.47 3.66e-8 Electrocardiographic conduction measures; TGCT cis rs6964587 0.967 rs10280620 chr7:91582183 C/G cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg27588902 chr6:42928151 GNMT -0.56 -6.8 -0.52 4.02e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2439831 0.702 rs28699233 chr15:44122866 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.89 5.79 0.46 5.46e-8 Lung cancer in ever smokers; TGCT cis rs11971779 0.680 rs7801613 chr7:139039927 A/G cg07862535 chr7:139043722 LUC7L2 -0.57 -4.52 -0.38 1.42e-5 Diisocyanate-induced asthma; TGCT cis rs7647973 0.925 rs7429661 chr3:49228800 G/A cg07636037 chr3:49044803 WDR6 0.65 5.26 0.43 6.25e-7 Menarche (age at onset); TGCT cis rs9905704 0.647 rs3809723 chr17:57061978 T/G cg05425664 chr17:57184151 TRIM37 -0.58 -4.71 -0.39 6.56e-6 Testicular germ cell tumor; TGCT cis rs2856321 1.000 rs11054423 chr12:11859731 A/G cg11375112 chr12:11883006 ETV6 0.3 4.48 0.37 1.67e-5 Height; TGCT cis rs651907 0.535 rs12631513 chr3:101517476 A/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs9467711 0.659 rs66757203 chr6:26454956 C/T cg16898833 chr6:26189333 HIST1H4D 1.24 5.8 0.46 5.12e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 1.000 rs59708460 chr8:58196526 G/A cg22535103 chr8:58192502 C8orf71 -0.39 -4.55 -0.38 1.24e-5 Developmental language disorder (linguistic errors); TGCT cis rs10986311 0.802 rs7049097 chr9:127110457 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.86 0.4 3.52e-6 Vitiligo; TGCT cis rs2255336 0.616 rs6488285 chr12:10518706 G/A cg16084090 chr12:10586130 KLRC2 0.3 4.62 0.38 9.55e-6 Blood protein levels; TGCT cis rs9926296 0.618 rs8058179 chr16:89846987 C/T cg21285383 chr16:89894308 SPIRE2 -0.34 -4.71 -0.39 6.54e-6 Vitiligo; TGCT cis rs9527 0.525 rs12770034 chr10:104635595 A/G cg15744005 chr10:104629667 AS3MT -0.47 -5.86 -0.47 3.9e-8 Arsenic metabolism; TGCT cis rs2980439 0.557 rs2976876 chr8:8318850 T/C cg06636001 chr8:8085503 FLJ10661 0.79 7.34 0.55 2.4e-11 Neuroticism; TGCT cis rs4595586 0.545 rs2197940 chr12:39401937 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs11792861 0.816 rs744980 chr9:111690388 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 4.92 0.4 2.68e-6 Menarche (age at onset); TGCT cis rs2404602 0.716 rs66754747 chr15:76828568 G/A cg26408565 chr15:76604113 ETFA -0.37 -4.74 -0.39 5.83e-6 Blood metabolite levels; TGCT trans rs66573146 0.634 rs56097119 chr4:7018692 C/G cg07817883 chr1:32538562 TMEM39B 1.28 7.0 0.53 1.39e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs8013055 0.796 rs4074937 chr14:106000977 A/G cg25008857 chr14:105974488 NA 0.26 4.67 0.39 7.64e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs1577917 0.916 rs12203358 chr6:86603224 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.6 -0.45 1.34e-7 Response to antipsychotic treatment; TGCT cis rs6484504 0.532 rs2150212 chr11:31255935 G/A cg14844989 chr11:31128820 NA -0.25 -4.84 -0.4 3.76e-6 Red blood cell count; TGCT cis rs4819052 0.851 rs28501512 chr21:46676702 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs981844 0.712 rs4292309 chr4:154745178 C/A cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT trans rs28595532 0.557 rs4359977 chr4:119314055 T/C cg26518628 chr1:97050305 NA -0.5 -7.26 -0.55 3.79e-11 Cannabis dependence symptom count; TGCT cis rs75686122 0.892 rs57252025 chr8:104547758 G/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9787249 0.874 rs12094291 chr1:40226046 G/A cg19912559 chr1:40204330 PPIE 0.47 5.5 0.44 2.05e-7 Blood protein levels; TGCT cis rs10186029 0.509 rs6718004 chr2:213945280 A/T cg08319019 chr2:214017104 IKZF2 0.61 4.57 0.38 1.14e-5 Systemic sclerosis; TGCT cis rs6952808 0.691 rs2398709 chr7:2112548 C/T cg04267008 chr7:1944627 MAD1L1 -0.38 -4.85 -0.4 3.61e-6 Bipolar disorder and schizophrenia; TGCT cis rs4803468 1.000 rs1043413 chr19:41939297 C/G cg09537434 chr19:41945824 ATP5SL 0.91 10.21 0.68 3.82e-18 Height; TGCT cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg21951975 chr1:209979733 IRF6 -0.57 -6.17 -0.48 8.98e-9 Monobrow; TGCT cis rs4821897 0.514 rs739141 chr22:39824450 A/G cg05872129 chr22:39784769 NA 0.94 10.97 0.7 5.66e-20 IgG glycosylation; TGCT cis rs2456568 0.802 rs10765640 chr11:93636462 C/T cg17595323 chr11:93583763 C11orf90 -0.47 -6.44 -0.5 2.38e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg06238570 chr21:40685208 BRWD1 -0.83 -9.08 -0.63 2.06e-15 Cognitive function; TGCT cis rs12780845 0.540 rs6602180 chr10:17192362 T/C cg01003015 chr10:17271136 VIM 0.58 5.25 0.43 6.37e-7 Homocysteine levels; TGCT cis rs4704846 1.000 rs415392 chr5:156546990 C/T cg12943317 chr5:156479607 HAVCR1 -0.31 -4.51 -0.38 1.51e-5 Blood protein levels; TGCT cis rs554111 0.656 rs10799682 chr1:21424030 G/C cg01072550 chr1:21505969 NA 0.36 5.46 0.44 2.51e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs829883 0.639 rs829898 chr12:98857675 A/C cg25150519 chr12:98850993 NA 0.64 7.54 0.56 8.56e-12 Colorectal adenoma (advanced); TGCT cis rs909002 0.800 rs4949454 chr1:32099041 A/G cg11573219 chr1:32083031 HCRTR1 0.43 5.6 0.45 1.33e-7 Intelligence (multi-trait analysis); TGCT cis rs9894429 0.789 rs8074989 chr17:79598728 G/C cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs763121 0.925 rs9611008 chr22:39098787 T/C cg06022373 chr22:39101656 GTPBP1 0.76 7.85 0.58 1.7e-12 Menopause (age at onset); TGCT cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT trans rs8073060 0.586 rs225307 chr17:33918311 A/G cg19694781 chr19:47549865 TMEM160 0.6 13.04 0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs873946 0.689 rs2803993 chr10:134550606 T/C cg26818010 chr10:134567672 INPP5A -0.34 -4.51 -0.38 1.51e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg24675658 chr1:53192096 ZYG11B -0.8 -9.75 -0.66 5.01e-17 Monocyte count; TGCT cis rs6542838 0.702 rs4851177 chr2:99535188 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.44 -0.44 2.74e-7 Fear of minor pain; TGCT trans rs696279 0.967 rs697510 chr7:16700553 C/T cg14841483 chr5:131310671 ACSL6 0.4 7.04 0.53 1.19e-10 Mean platelet volume; TGCT cis rs57244997 0.790 rs73026528 chr6:162384271 T/C cg17173639 chr6:162384350 PARK2 -0.5 -4.69 -0.39 7.19e-6 Mosquito bite size; TGCT cis rs77106637 1.000 rs3862791 chr11:72501002 C/T cg03713592 chr11:72463424 ARAP1 0.97 6.35 0.5 3.68e-9 Type 2 diabetes; TGCT cis rs939574 0.818 rs6744146 chr2:220070597 T/A cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.06 -6.52 -0.51 1.6e-9 Platelet distribution width; TGCT cis rs9814567 1.000 rs9968172 chr3:134231251 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.97 9.45 0.65 2.73e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2072499 0.778 rs2842868 chr1:156196407 A/C cg24450063 chr1:156163899 SLC25A44 1.03 9.7 0.66 6.78e-17 Testicular germ cell tumor; TGCT cis rs12615966 1.000 rs6744707 chr2:105371087 G/A cg16465502 chr2:105461796 NA 0.81 4.47 0.37 1.76e-5 Pancreatic cancer; TGCT cis rs9814567 0.964 rs4539979 chr3:134287597 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs806215 0.526 rs62481419 chr7:127488007 A/G cg11539674 chr7:127291444 SND1 -0.36 -4.67 -0.39 7.77e-6 Type 2 diabetes; TGCT trans rs10802346 0.524 rs10802356 chr1:246385857 T/C cg22732515 chr19:44031385 ETHE1 0.83 6.62 0.51 9.79e-10 Fractional exhaled nitric oxide (childhood); TGCT trans rs4332037 0.901 rs11767040 chr7:1945468 C/T cg10840412 chr1:235813424 GNG4 1.03 8.1 0.59 4.34e-13 Bipolar disorder; TGCT cis rs6459804 0.566 rs113592117 chr7:157511889 C/A cg14168080 chr7:157504135 PTPRN2 -0.42 -4.89 -0.4 3.08e-6 Bipolar disorder and schizophrenia; TGCT cis rs9467773 0.901 rs1407045 chr6:26476155 A/G cg09904177 chr6:26538194 HMGN4 0.59 5.55 0.45 1.66e-7 Intelligence (multi-trait analysis); TGCT cis rs2729354 1.000 rs2729354 chr11:57355970 A/G cg24343310 chr11:57249947 NA 0.28 4.8 0.4 4.5e-6 Blood protein levels; TGCT cis rs1971136 1 rs1971136 chr2:25291539 C/T cg15423357 chr2:25149977 NA -0.6 -6.12 -0.48 1.15e-8 Breast cancer; TGCT cis rs739496 0.947 rs2239195 chr12:111881309 G/T cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs3087591 0.708 rs67065748 chr17:29605631 T/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.21 0.54 4.8e-11 Hip circumference; TGCT cis rs11239930 0.538 rs9663073 chr1:146554571 A/G cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs78366141 0.649 rs77135481 chr4:89689680 T/C cg01026744 chr4:89619053 NAP1L5;HERC3 1.26 5.58 0.45 1.43e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs4455778 0.538 rs6583513 chr7:49123526 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs1008375 0.966 rs3775925 chr4:17588437 A/G cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs67311347 1.000 rs1004655 chr3:40490009 G/A cg13409248 chr3:40428643 ENTPD3 0.57 4.6 0.38 1.03e-5 Renal cell carcinoma; TGCT cis rs11779988 0.629 rs11780813 chr8:17856014 T/C cg01800426 chr8:17659068 MTUS1 -0.55 -4.77 -0.39 5e-6 Breast cancer; TGCT cis rs9911578 1.000 rs172565 chr17:56808996 A/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.626 rs62262722 chr3:49769419 G/C cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.59 -0.38 1.08e-5 Menarche (age at onset); TGCT cis rs67478160 0.619 rs3742365 chr14:104198251 A/G cg26031613 chr14:104095156 KLC1 -0.72 -7.35 -0.55 2.38e-11 Schizophrenia; TGCT cis rs2251381 0.778 rs2471947 chr21:30534219 G/T cg24692254 chr21:30365293 RNF160 0.76 7.56 0.56 7.88e-12 Selective IgA deficiency; TGCT cis rs1005277 0.579 rs1780130 chr10:38485378 T/A cg25427524 chr10:38739819 LOC399744 -0.4 -8.5 -0.61 5.12e-14 Extrinsic epigenetic age acceleration; TGCT cis rs769267 0.965 rs13964 chr19:19468710 C/G cg03709012 chr19:19516395 GATAD2A -0.69 -5.76 -0.46 6.23e-8 Tonsillectomy; TGCT cis rs9611565 0.592 rs80477 chr22:42001183 C/T cg06634786 chr22:41940651 POLR3H 0.83 7.74 0.57 3.07e-12 Vitiligo; TGCT cis rs1552244 0.572 rs57268864 chr3:10164233 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs1577917 1.000 rs12154056 chr6:86634094 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs921968 0.643 rs13431399 chr2:219469498 G/C cg02176678 chr2:219576539 TTLL4 -0.49 -6.85 -0.52 3.03e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs514406 0.683 rs10157120 chr1:53210888 A/G cg25767906 chr1:53392781 SCP2 -0.44 -4.87 -0.4 3.27e-6 Monocyte count; TGCT cis rs751728 0.965 rs9394168 chr6:33759701 T/A cg13859433 chr6:33739653 LEMD2 -0.39 -7.23 -0.54 4.25e-11 Crohn's disease; TGCT cis rs6430585 0.583 rs73957037 chr2:136588031 C/A cg07169764 chr2:136633963 MCM6 1.05 9.48 0.65 2.35e-16 Corneal structure; TGCT cis rs36051895 0.589 rs7874785 chr9:5196695 C/T cg02405213 chr9:5042618 JAK2 0.69 8.29 0.6 1.62e-13 Pediatric autoimmune diseases; TGCT cis rs929354 0.742 rs11980541 chr7:156988776 G/C cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs9921338 0.924 rs7202024 chr16:11440758 A/G cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.37e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs7267979 0.844 rs869358 chr20:25374674 A/G cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2066819 1.000 rs17118439 chr12:56667604 C/T cg26714650 chr12:56694279 CS 1.36 6.06 0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs6088590 1.000 rs6120747 chr20:33449769 T/C cg24642439 chr20:33292090 TP53INP2 0.71 6.23 0.49 6.54e-9 Coronary artery disease; TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.74e-6 Prudent dietary pattern; TGCT trans rs797680 0.927 rs797675 chr1:93674226 A/T cg27528825 chr2:159282178 CCDC148 -0.34 -6.7 -0.52 6.63e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg05985448 chr10:134359359 INPP5A 0.23 4.97 0.41 2.19e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7666738 0.830 rs2903152 chr4:99067992 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs80282103 0.867 rs11250242 chr10:1100064 A/C cg08668510 chr10:1095578 IDI1 -1.35 -5.47 -0.44 2.36e-7 Glomerular filtration rate (creatinine); TGCT cis rs854765 0.547 rs7223696 chr17:17915791 G/T cg04398451 chr17:18023971 MYO15A -0.31 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT cis rs3760982 0.546 rs73048681 chr19:44289945 T/C cg12072164 chr19:44306565 LYPD5 0.4 5.45 0.44 2.63e-7 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs3087591 0.708 rs4794887 chr17:29649696 G/A cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT cis rs881375 1.000 rs4323544 chr9:123647377 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.47 0.37 1.74e-5 Rheumatoid arthritis; TGCT cis rs7918232 1.000 rs6482595 chr10:27380261 A/G cg14442939 chr10:27389572 ANKRD26 -0.75 -6.32 -0.49 4.22e-9 Breast cancer; TGCT cis rs6988636 1.000 rs61422480 chr8:124188940 C/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs4494114 0.967 rs9438977 chr1:39354958 A/G cg25970120 chr1:39325951 RRAGC -0.54 -5.5 -0.44 2.07e-7 Blood protein levels; TGCT cis rs6964587 1.000 rs60147309 chr7:91736098 C/G cg17063962 chr7:91808500 NA 0.87 9.34 0.64 4.87e-16 Breast cancer; TGCT cis rs2836974 0.565 rs2836939 chr21:40578546 C/T cg11644478 chr21:40555479 PSMG1 0.77 5.8 0.46 5.23e-8 Cognitive function; TGCT trans rs57221529 0.766 rs1399381 chr5:589853 G/T cg25482853 chr8:67687455 SGK3 1.2 10.12 0.67 6.42e-18 Lung disease severity in cystic fibrosis; TGCT cis rs1729951 0.575 rs361237 chr3:136702414 A/G cg21827317 chr3:136751795 NA 0.37 5.2 0.42 8.02e-7 Neuroticism; TGCT cis rs2197308 0.765 rs7295711 chr12:37903631 C/T cg13010199 chr12:38710504 ALG10B 0.67 5.38 0.44 3.57e-7 Morning vs. evening chronotype; TGCT cis rs2439831 0.867 rs2614811 chr15:43913487 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.91 6.47 0.5 2.09e-9 Lung cancer in ever smokers; TGCT cis rs1153858 1.000 rs16942000 chr15:45633003 C/T cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs826838 0.935 rs11169508 chr12:39173385 C/T cg26384229 chr12:38710491 ALG10B 1.0 8.98 0.63 3.56e-15 Heart rate; TGCT cis rs9926296 0.632 rs7184315 chr16:89799373 C/G cg04287289 chr16:89883240 FANCA -0.64 -6.49 -0.5 1.82e-9 Vitiligo; TGCT cis rs3858526 0.883 rs10769326 chr11:5934358 C/T cg05234568 chr11:5960015 NA -0.45 -4.58 -0.38 1.13e-5 DNA methylation (variation); TGCT cis rs67385638 0.962 rs2187608 chr11:5269931 G/C cg12559170 chr11:5275217 HBG2 0.49 9.25 0.64 8.41e-16 Hemoglobin levels; TGCT cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs986417 1.000 rs2093212 chr14:60843322 G/A cg27398547 chr14:60952738 C14orf39 -1.37 -8.31 -0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs7666738 0.822 rs979946 chr4:98921235 C/A cg05340658 chr4:99064831 C4orf37 0.53 6.1 0.48 1.24e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs7659604 0.676 rs4077102 chr4:122699830 A/G cg06713675 chr4:122721982 EXOSC9 -0.62 -8.48 -0.61 5.69e-14 Type 2 diabetes; TGCT cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg11941060 chr3:133502564 NA -0.26 -5.32 -0.43 4.74e-7 Iron status biomarkers; TGCT cis rs986417 0.579 rs1254281 chr14:60854300 T/C cg27398547 chr14:60952738 C14orf39 -1.45 -10.38 -0.68 1.52e-18 Gut microbiota (bacterial taxa); TGCT cis rs769267 0.930 rs6909 chr19:19619542 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs1018836 0.774 rs35159732 chr8:91633094 A/G cg16814680 chr8:91681699 NA -0.92 -9.45 -0.65 2.72e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6426558 0.537 rs4653813 chr1:227461510 G/C cg10327440 chr1:227177885 CDC42BPA 0.58 6.76 0.52 4.75e-10 Neutrophil percentage of white cells; TGCT cis rs8014204 0.804 rs7154845 chr14:75247746 A/G cg06637938 chr14:75390232 RPS6KL1 0.7 6.75 0.52 5.06e-10 Caffeine consumption; TGCT cis rs7226408 0.948 rs11662292 chr18:34399694 T/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs2153535 0.584 rs9502723 chr6:8541504 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.61 0.45 1.23e-7 Motion sickness; TGCT cis rs3764563 1.000 rs4239617 chr19:15741537 C/T cg20725493 chr19:15740067 CYP4F8 -0.43 -4.67 -0.39 7.75e-6 Inflammatory biomarkers; TGCT cis rs611744 0.647 rs1448151 chr8:109276283 C/A cg21045802 chr8:109455806 TTC35 0.72 7.39 0.55 1.94e-11 Dupuytren's disease; TGCT cis rs7020830 0.898 rs12554874 chr9:37073902 C/T cg14294708 chr9:37120828 ZCCHC7 1.28 19.85 0.87 2.54e-40 Schizophrenia; TGCT cis rs10501293 0.746 rs1489200 chr11:43005220 G/A cg03447554 chr11:43094025 NA 0.44 6.38 0.5 3.26e-9 Cognitive performance; TGCT cis rs13191362 1.000 rs34192365 chr6:163012382 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12477438 0.501 rs12992218 chr2:99753834 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs7940866 0.874 rs10791113 chr11:130873165 A/G cg05962950 chr11:130786565 SNX19 0.67 6.61 0.51 1.02e-9 Schizophrenia; TGCT cis rs10791097 0.967 rs10750450 chr11:130719061 G/T cg05962950 chr11:130786565 SNX19 0.75 8.13 0.59 3.73e-13 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10037670 0.557 rs972596 chr5:153824197 A/G cg21964928 chr5:153872958 NA 0.28 5.1 0.42 1.22e-6 Behavioural disinhibition (generation interaction); TGCT cis rs1153858 1.000 rs3809472 chr15:45694318 G/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs1005277 0.579 rs2474595 chr10:38426782 C/G cg25427524 chr10:38739819 LOC399744 0.4 8.22 0.59 2.34e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2014572 0.875 rs10405008 chr19:57753643 C/G cg24459738 chr19:57751996 ZNF805 0.59 5.77 0.46 5.84e-8 Hyperactive-impulsive symptoms; TGCT cis rs2880765 0.631 rs55767890 chr15:86004142 C/G cg13263323 chr15:86062960 AKAP13 -0.2 -4.48 -0.37 1.68e-5 Coronary artery disease; TGCT trans rs2727020 0.553 rs61904166 chr11:49581461 T/C cg03929089 chr4:120376271 NA -0.64 -7.36 -0.55 2.21e-11 Coronary artery disease; TGCT cis rs7617773 0.817 rs4131361 chr3:48328812 T/C cg11946769 chr3:48343235 NME6 0.74 6.34 0.49 3.97e-9 Coronary artery disease; TGCT trans rs459571 0.916 rs467303 chr9:136904835 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.72 -7.83 -0.58 1.87e-12 Platelet distribution width; TGCT cis rs9660992 0.548 rs1172152 chr1:205220718 T/A cg00857998 chr1:205179979 DSTYK 0.49 4.47 0.37 1.76e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs13177918 0.677 rs4541646 chr5:149822918 G/A cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs60843830 1.000 rs3791223 chr2:222336 T/C cg00108164 chr2:264199 ACP1;SH3YL1 0.74 6.76 0.52 4.93e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs61990749 0.597 rs2267768 chr14:78216014 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs7647973 0.587 rs10452032 chr3:49680973 G/A cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs131777 0.577 rs5770928 chr22:51029091 G/C cg25309564 chr22:51001381 C22orf41 0.55 5.11 0.42 1.2e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7572733 0.534 rs1401091 chr2:198790423 T/G cg00792783 chr2:198669748 PLCL1 -0.57 -5.14 -0.42 1.03e-6 Dermatomyositis; TGCT cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs7611238 0.560 rs13325966 chr3:195072841 T/G cg27323046 chr3:195102265 ACAP2 0.36 4.88 0.4 3.23e-6 Body mass index; TGCT cis rs1218582 0.741 rs883718 chr1:154846274 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.63 -6.45 -0.5 2.29e-9 Prostate cancer; TGCT cis rs4654899 0.743 rs61781069 chr1:21130735 T/C cg01072550 chr1:21505969 NA -0.46 -6.79 -0.52 4.06e-10 Superior frontal gyrus grey matter volume; TGCT cis rs2629540 0.824 rs10901809 chr10:126410804 C/T cg08799069 chr10:126477246 METTL10 0.28 4.63 0.38 9.24e-6 Cocaine dependence; TGCT cis rs6671200 1.000 rs71654418 chr1:95662658 G/T cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs1784581 0.588 rs7451121 chr6:162412344 A/G cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.07e-9 Itch intensity from mosquito bite; TGCT cis rs7666738 0.830 rs13140676 chr4:98804978 C/T cg18180107 chr4:99064573 C4orf37 0.53 5.05 0.41 1.51e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2370759 1.000 rs16933177 chr10:32565705 G/A cg01819863 chr10:32635814 EPC1 1.03 9.87 0.66 2.63e-17 Sexual dysfunction (female); TGCT cis rs1008375 1.000 rs917665 chr4:17668504 A/C cg10189774 chr4:17578691 LAP3 -0.5 -4.51 -0.38 1.47e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7192750 0.562 rs9302631 chr16:71943414 C/T cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7829975 0.564 rs2921060 chr8:8317817 G/T cg15556689 chr8:8085844 FLJ10661 -0.65 -6.23 -0.49 6.59e-9 Mood instability; TGCT cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg10802521 chr3:52805072 NEK4 0.79 10.01 0.67 1.18e-17 Bipolar disorder; TGCT cis rs9911578 0.835 rs9904993 chr17:56468569 G/T cg05425664 chr17:57184151 TRIM37 0.61 5.71 0.46 8.06e-8 Intelligence (multi-trait analysis); TGCT cis rs705471 0.762 rs7919625 chr10:3669970 A/G cg14308648 chr10:3568949 NA 0.25 4.44 0.37 1.95e-5 Capecitabine sensitivity; TGCT cis rs12510870 0.599 rs4574378 chr4:74402790 G/T cg05868023 chr4:75230803 EREG 0.56 5.14 0.42 1.06e-6 Iris color (b* coordinate); TGCT cis rs2115630 1.000 rs8037423 chr15:85355494 C/T cg17173187 chr15:85201210 NMB -0.39 -4.82 -0.4 4.06e-6 P wave terminal force; TGCT cis rs11809207 1.000 rs34587428 chr1:26522392 C/T cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg12419862 chr22:24373484 LOC391322 0.88 7.71 0.57 3.51e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs12893668 0.645 rs12889403 chr14:104034746 C/T cg26031613 chr14:104095156 KLC1 -0.54 -4.45 -0.37 1.88e-5 Reticulocyte count; TGCT trans rs6089829 0.962 rs4809455 chr20:61660781 G/C cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9486719 1.000 rs2145535 chr6:97034715 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs2730245 0.661 rs842696 chr7:158662698 T/C cg11984989 chr7:158649758 WDR60 1.07 9.87 0.66 2.58e-17 Height; TGCT cis rs1109861 0.525 rs606139 chr10:11205719 A/G cg20379239 chr10:11207015 CUGBP2 0.47 4.99 0.41 2e-6 Urinary albumin-to-creatinine ratio; TGCT cis rs9818758 0.556 rs9880309 chr3:49304329 G/C cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs10791097 0.694 rs7926167 chr11:130745045 T/C cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7267979 1.000 rs1077889 chr20:25267893 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1865760 0.566 rs2032445 chr6:26044812 T/A cg17042849 chr6:26104293 HIST1H4C -0.6 -5.17 -0.42 8.99e-7 Height; TGCT cis rs6840360 0.571 rs62329101 chr4:152512239 G/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs4713118 0.662 rs9468278 chr6:28028482 C/T cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs7666738 0.830 rs4699594 chr4:98980775 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs360798 0.512 rs6545973 chr2:63089434 C/T cg17519650 chr2:63277830 OTX1 0.65 5.62 0.45 1.19e-7 Coronary artery disease; TGCT cis rs11085466 0.948 rs11668453 chr19:21759357 C/A cg02997983 chr19:21646781 NA -0.64 -4.52 -0.38 1.43e-5 Colorectal or endometrial cancer; TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg11003573 chr3:44754125 ZNF502 -0.43 -4.97 -0.41 2.18e-6 Depressive symptoms; TGCT cis rs12900413 0.562 rs12898229 chr15:90295960 C/T cg24249390 chr15:90295951 MESP1 -0.3 -5.13 -0.42 1.07e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2456568 0.548 rs6483281 chr11:93661840 G/C cg26875233 chr11:93583750 C11orf90 -0.41 -4.94 -0.41 2.43e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2832191 0.903 rs11700687 chr21:30486767 A/G cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs9467773 1.000 rs1321480 chr6:26532742 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.49 0.5 1.89e-9 Intelligence (multi-trait analysis); TGCT cis rs9948 0.655 rs56913233 chr2:97405896 A/G cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg13683864 chr3:40499215 RPL14 -1.15 -12.35 -0.74 2.5e-23 Renal cell carcinoma; TGCT cis rs7681440 0.869 rs894280 chr4:90760883 C/T cg20003494 chr4:90757398 SNCA -0.63 -6.03 -0.48 1.73e-8 Dementia with Lewy bodies; TGCT cis rs6089584 1.000 rs6089587 chr20:60564829 C/T cg16423285 chr20:60520624 NA -0.52 -5.62 -0.45 1.18e-7 Body mass index; TGCT cis rs10836699 0.741 rs1381158 chr11:37180913 A/C cg18520238 chr11:36422557 PRR5L 0.17 4.44 0.37 1.94e-5 Low high density lipoprotein cholesterol levels; TGCT cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg23719950 chr11:63933701 MACROD1 -0.71 -5.91 -0.47 3.06e-8 Mean platelet volume; TGCT cis rs36051895 0.658 rs10974914 chr9:5014332 C/T cg02405213 chr9:5042618 JAK2 -0.78 -10.93 -0.7 6.86e-20 Pediatric autoimmune diseases; TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs12421382 0.507 rs11600810 chr11:109356443 G/A cg16359550 chr11:109292809 C11orf87 0.7 7.43 0.55 1.55e-11 Schizophrenia; TGCT cis rs7829975 0.560 rs4841013 chr8:8552013 A/G cg15556689 chr8:8085844 FLJ10661 -0.54 -4.61 -0.38 1e-5 Mood instability; TGCT cis rs13217239 0.646 rs12201393 chr6:26975690 C/A cg05738196 chr6:26577821 NA 0.49 4.77 0.39 4.98e-6 Schizophrenia; TGCT cis rs2204008 0.749 rs10880692 chr12:38592918 C/G cg26384229 chr12:38710491 ALG10B -0.92 -8.4 -0.6 8.58e-14 Bladder cancer; TGCT cis rs4819052 0.851 rs2838866 chr21:46713014 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 6.71 0.52 6.33e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs782590 0.902 rs3762513 chr2:55762957 C/T cg03859395 chr2:55845619 SMEK2 0.93 11.51 0.72 2.68e-21 Metabolic syndrome; TGCT cis rs10114408 0.801 rs6479519 chr9:96663421 A/G cg13679303 chr9:96623674 NA -0.36 -4.61 -0.38 9.97e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs782590 0.774 rs782629 chr2:55900283 C/T cg03859395 chr2:55845619 SMEK2 -0.84 -9.75 -0.66 4.99e-17 Metabolic syndrome; TGCT cis rs17122693 0.748 rs72681608 chr14:51116090 C/T cg04730355 chr14:51134070 SAV1 1.35 12.44 0.75 1.47e-23 Cognitive performance; TGCT cis rs3617 0.539 rs4687689 chr3:52948674 A/C cg10802521 chr3:52805072 NEK4 0.59 6.77 0.52 4.48e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3733585 0.699 rs7663079 chr4:9966771 T/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.87 -0.58 1.53e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs35306767 0.807 rs34885925 chr10:919032 G/C cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg20007245 chr22:24372913 LOC391322 -0.64 -6.07 -0.48 1.44e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11030122 0.632 rs11030599 chr11:4031677 A/G cg18678763 chr11:4115507 RRM1 -0.49 -6.16 -0.48 9.44e-9 Mean platelet volume;Platelet distribution width; TGCT cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg09436375 chr6:42928200 GNMT -0.41 -5.38 -0.43 3.6e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2836974 0.897 rs2026267 chr21:40711477 C/A cg11890956 chr21:40555474 PSMG1 1.02 9.9 0.66 2.16e-17 Cognitive function; TGCT cis rs2469997 1.000 rs2470014 chr8:120360820 C/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg13695892 chr22:41940480 POLR3H -0.76 -7.43 -0.56 1.54e-11 Vitiligo; TGCT cis rs6450176 1.000 rs4334835 chr5:53300612 T/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2404602 0.503 rs284909 chr15:76736628 C/T cg22467129 chr15:76604101 ETFA -0.42 -4.71 -0.39 6.46e-6 Blood metabolite levels; TGCT cis rs4819052 0.851 rs2255774 chr21:46683851 A/T cg06618935 chr21:46677482 NA -0.36 -5.7 -0.46 8.16e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4478858 0.735 rs3806255 chr1:31791578 A/G cg00250761 chr1:31883323 NA -0.27 -4.84 -0.4 3.76e-6 Alcohol dependence; TGCT cis rs3796352 0.881 rs11710394 chr3:53015839 A/G cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT trans rs1814175 0.817 rs1615305 chr11:49895222 T/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.63e-13 Height; TGCT cis rs12908161 0.959 rs34342559 chr15:85331271 A/G cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.1e-8 Schizophrenia; TGCT cis rs4665809 0.838 rs6546749 chr2:26306288 T/C cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT trans rs877282 0.945 rs35342920 chr10:790484 T/C cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs10901296 0.702 rs11244178 chr9:133766008 C/T cg03924115 chr9:133768966 QRFP -0.27 -4.43 -0.37 2.01e-5 Bilirubin levels; TGCT cis rs2404602 0.716 rs2404736 chr15:76875943 T/C cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.08e-6 Blood metabolite levels; TGCT cis rs9653442 0.545 rs2009095 chr2:100765081 C/T cg07810366 chr2:100720526 AFF3 -0.37 -5.46 -0.44 2.46e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2880765 0.835 rs12708553 chr15:86046833 C/G cg13263323 chr15:86062960 AKAP13 0.23 4.75 0.39 5.62e-6 Coronary artery disease; TGCT cis rs68170813 0.559 rs2395881 chr7:107074323 A/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs7255045 0.788 rs2290688 chr19:12958697 T/C cg04657146 chr19:12876947 HOOK2 -0.61 -4.53 -0.38 1.35e-5 Mean corpuscular volume; TGCT cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg11890956 chr21:40555474 PSMG1 1.11 12.43 0.74 1.56e-23 Cognitive function; TGCT cis rs7829975 0.714 rs4841042 chr8:8664622 A/G cg06636001 chr8:8085503 FLJ10661 -0.66 -6.01 -0.47 1.93e-8 Mood instability; TGCT cis rs4786125 0.519 rs1388805 chr16:6929947 C/T cg03623568 chr16:6915990 A2BP1 -0.4 -5.63 -0.45 1.13e-7 Heart rate variability traits (SDNN); TGCT cis rs6460942 1.000 rs6460936 chr7:12404913 T/C cg06484146 chr7:12443880 VWDE -0.63 -5.65 -0.45 1.04e-7 Coronary artery disease; TGCT cis rs60871478 1.000 rs62432250 chr7:801792 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.64 0.38 8.77e-6 Cerebrospinal P-tau181p levels; TGCT cis rs2702888 0.501 rs2738161 chr8:6748597 C/T cg26795848 chr8:6756730 NA -0.32 -6.39 -0.5 3e-9 Blood pressure; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg15242686 chr22:24348715 GSTTP1 0.44 5.98 0.47 2.23e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6061231 0.724 rs1570027 chr20:60968596 A/G cg24112000 chr20:60950667 NA -0.4 -5.06 -0.41 1.44e-6 Colorectal cancer; TGCT cis rs7772486 0.625 rs9390355 chr6:146112942 C/T cg13319975 chr6:146136371 FBXO30 0.5 4.62 0.38 9.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6882046 0.513 rs454214 chr5:88003403 A/G cg22951263 chr5:87985283 NA 0.6 6.44 0.5 2.44e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs909341 0.830 rs1623866 chr20:62333022 G/A cg14758556 chr20:62440591 NA 0.29 4.48 0.37 1.71e-5 Atopic dermatitis; TGCT cis rs2115630 0.691 rs8040066 chr15:85176465 G/C cg17173187 chr15:85201210 NMB -0.47 -5.94 -0.47 2.67e-8 P wave terminal force; TGCT cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.56e-7 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.817 rs4881658 chr11:49941123 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.12 -0.54 7.75e-11 Height; TGCT cis rs6988636 1.000 rs13259806 chr8:124190103 A/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs9549260 0.567 rs7332730 chr13:41265979 C/A cg21288729 chr13:41239152 FOXO1 0.98 9.67 0.66 8.01e-17 Red blood cell count; TGCT cis rs72717009 0.825 rs61802846 chr1:161473873 A/C cg23840854 chr1:161414152 NA -0.98 -5.87 -0.47 3.79e-8 Rheumatoid arthritis; TGCT cis rs11030122 0.702 rs10835403 chr11:3990941 A/C cg18678763 chr11:4115507 RRM1 0.46 5.09 0.42 1.31e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs9650657 0.801 rs2409663 chr8:10643233 G/T cg27411982 chr8:10470053 RP1L1 -0.22 -4.62 -0.38 9.66e-6 Neuroticism; TGCT cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg07507251 chr3:52567010 NT5DC2 0.45 6.49 0.5 1.85e-9 Bipolar disorder; TGCT cis rs6938 0.534 rs11072512 chr15:75204026 C/T cg10253484 chr15:75165896 SCAMP2 -0.57 -5.28 -0.43 5.69e-7 Breast cancer; TGCT cis rs250677 0.524 rs40521 chr5:148439639 C/T cg18129178 chr5:148520854 ABLIM3 0.35 5.01 0.41 1.85e-6 Breast cancer; TGCT cis rs9796 0.576 rs13329511 chr15:41299121 T/C cg18705301 chr15:41695430 NDUFAF1 -0.5 -6.47 -0.5 2.05e-9 Menopause (age at onset); TGCT cis rs919433 0.519 rs700656 chr2:198653667 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs1552244 0.554 rs7349576 chr3:10050893 T/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs875971 0.895 rs7782806 chr7:65657897 C/T cg11764359 chr7:65958608 NA -0.56 -5.06 -0.41 1.45e-6 Aortic root size; TGCT cis rs644799 1.000 rs488246 chr11:95560473 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7666738 0.830 rs10010223 chr4:99021758 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1371867 0.846 rs1788191 chr8:101260844 C/T cg06636551 chr8:101224915 SPAG1 0.49 6.83 0.52 3.32e-10 Atrioventricular conduction; TGCT cis rs6121246 0.909 rs7272062 chr20:30259145 A/G cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs644799 1.000 rs693364 chr11:95621926 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.73 7.25 0.55 3.86e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6977955 1.000 rs10951192 chr7:28161033 C/G cg23620719 chr7:28220237 JAZF1 -0.7 -5.33 -0.43 4.47e-7 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.95 -6.11 -0.48 1.17e-8 Alzheimer's disease; TGCT cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.93 10.08 0.67 8.27e-18 Intelligence (multi-trait analysis); TGCT cis rs10507380 0.825 rs9512639 chr13:27920666 C/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs67311347 0.544 rs12054197 chr3:40337562 C/T cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg13395646 chr4:1353034 KIAA1530 -0.36 -4.62 -0.38 9.52e-6 Obesity-related traits; TGCT cis rs7113874 0.610 rs7947670 chr11:8525531 A/C cg14521421 chr11:8862019 ST5 0.28 4.44 0.37 1.99e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7267979 1.000 rs6050617 chr20:25421648 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1864729 0.748 rs2635165 chr8:98296209 T/C cg08679828 chr8:102218111 ZNF706 -1.06 -6.94 -0.53 1.93e-10 Estradiol plasma levels (breast cancer); TGCT cis rs2354432 0.556 rs11239965 chr1:146753907 C/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs317689 0.819 rs317664 chr12:69704747 C/A cg14784868 chr12:69753453 YEATS4 0.57 4.9 0.4 2.96e-6 Response to diuretic therapy; TGCT trans rs2727020 0.658 rs4980431 chr11:49350071 G/T cg03929089 chr4:120376271 NA -0.69 -7.95 -0.58 9.7e-13 Coronary artery disease; TGCT cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg15659132 chr6:26577336 NA 0.87 10.79 0.7 1.52e-19 Intelligence (multi-trait analysis); TGCT cis rs6964587 0.869 rs6975243 chr7:91514672 G/A cg17063962 chr7:91808500 NA -0.86 -9.19 -0.64 1.16e-15 Breast cancer; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.33 0.55 2.59e-11 Prudent dietary pattern; TGCT cis rs16866061 1.000 rs2047134 chr2:225347713 A/C cg12698349 chr2:225449008 CUL3 1.01 9.93 0.67 1.87e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs9972944 0.756 rs6416945 chr17:63763942 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.29 -0.43 5.45e-7 Total body bone mineral density; TGCT cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs1215050 0.791 rs260899 chr4:98707046 G/A cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9682041 0.932 rs9841852 chr3:170067049 C/G cg11886554 chr3:170076028 SKIL 0.8 5.89 0.47 3.34e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7267979 0.934 rs2261753 chr20:25262291 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs208520 1.000 rs208523 chr6:66954195 G/C cg07460842 chr6:66804631 NA -0.83 -7.52 -0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs6570726 0.791 rs1935612 chr6:145906090 T/A cg23711669 chr6:146136114 FBXO30 0.85 9.24 0.64 8.9e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9291683 0.609 rs13141233 chr4:10028729 T/C cg00071950 chr4:10020882 SLC2A9 0.7 9.43 0.65 3.06e-16 Bone mineral density; TGCT cis rs9303401 0.659 rs36093395 chr17:56957357 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs79057730 0.599 rs4721086 chr7:821123 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.62 5.12 0.42 1.14e-6 Initial pursuit acceleration; TGCT cis rs600231 0.665 rs12790095 chr11:65326086 T/G cg21890820 chr11:65308645 LTBP3 0.4 5.08 0.42 1.33e-6 Bone mineral density; TGCT cis rs4237845 0.837 rs7954957 chr12:58299250 C/T cg02175503 chr12:58329896 NA 0.52 5.5 0.44 2.09e-7 Intelligence (multi-trait analysis); TGCT cis rs765787 0.556 rs12915965 chr15:45512647 T/C cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT cis rs3812831 0.572 rs3118896 chr13:114931769 C/G cg06611532 chr13:114900021 NA 0.31 5.62 0.45 1.19e-7 Schizophrenia; TGCT cis rs7772486 0.720 rs702320 chr6:146006654 G/A cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs80282103 0.618 rs74117849 chr10:1165425 A/G cg18964960 chr10:1102726 WDR37 1.03 4.53 0.38 1.39e-5 Glomerular filtration rate (creatinine); TGCT cis rs988913 1.000 rs960834 chr6:54823431 C/T cg04690482 chr6:54711388 FAM83B 0.3 4.57 0.38 1.16e-5 Menarche (age at onset); TGCT cis rs42648 0.869 rs10251227 chr7:89892286 T/G cg25739043 chr7:89950458 NA -0.64 -5.91 -0.47 3.16e-8 Homocysteine levels; TGCT cis rs35883536 0.647 rs2783696 chr1:101044089 G/A cg06223162 chr1:101003688 GPR88 0.41 7.55 0.56 7.99e-12 Monocyte count; TGCT cis rs7635838 0.892 rs9823197 chr3:11503133 A/T cg00170343 chr3:11313890 ATG7 0.6 5.29 0.43 5.3e-7 HDL cholesterol; TGCT cis rs7172809 0.599 rs59362734 chr15:77755406 A/C cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs9733 0.596 rs6661872 chr1:150628357 C/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs7043114 0.507 rs10992291 chr9:95033009 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.56 -5.5 -0.44 2.11e-7 Height; TGCT cis rs9486715 1.000 rs9486715 chr6:97059769 A/C cg06623918 chr6:96969491 KIAA0776 -1.11 -14.58 -0.79 1.16e-28 Headache; TGCT cis rs2836950 0.545 rs8132424 chr21:40584412 A/T cg11644478 chr21:40555479 PSMG1 0.51 4.78 0.39 4.83e-6 Menarche (age at onset); TGCT cis rs1826508 0.558 rs6505693 chr18:1206140 G/A cg23365097 chr18:515465 NA -0.46 -4.9 -0.4 2.87e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs12887734 0.566 rs3742366 chr14:104198351 T/C cg26031613 chr14:104095156 KLC1 -0.71 -6.03 -0.48 1.72e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg00786635 chr1:25594202 NA 0.56 5.95 0.47 2.54e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs3849570 0.961 rs3849571 chr3:81777716 A/C cg07356753 chr3:81810745 GBE1 -0.85 -8.17 -0.59 3.06e-13 Waist circumference;Body mass index; TGCT cis rs7312933 0.618 rs6582394 chr12:42686189 A/G cg19980929 chr12:42632907 YAF2 0.4 5.45 0.44 2.64e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs478304 0.651 rs4014192 chr11:65498915 C/T cg10518572 chr11:65560635 OVOL1 -0.24 -4.68 -0.39 7.53e-6 Acne (severe); TGCT cis rs9399137 0.507 rs56164974 chr6:135288716 C/T cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs2242116 0.727 rs7635480 chr3:46968227 T/C cg23352942 chr3:46931381 PTH1R -0.34 -5.13 -0.42 1.08e-6 Birth weight; TGCT cis rs2204008 0.869 rs34438288 chr12:38211582 G/T cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs10876993 0.890 rs115106209 chr12:58059331 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.88 -0.47 3.56e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg20007245 chr22:24372913 LOC391322 -0.78 -8.28 -0.6 1.66e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs854765 0.893 rs712265 chr17:18008447 G/A cg09796270 chr17:17721594 SREBF1 -0.26 -5.22 -0.42 7.3e-7 Total body bone mineral density; TGCT cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs12477438 0.520 rs2964969 chr2:99782811 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs9443645 0.901 rs9352667 chr6:79572296 A/G cg05283184 chr6:79620031 NA 0.21 4.71 0.39 6.64e-6 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.608 rs2724556 chr4:152341717 G/A cg17479576 chr4:152424074 FAM160A1 -0.5 -5.07 -0.41 1.43e-6 Intelligence (multi-trait analysis); TGCT cis rs6933660 0.720 rs6913515 chr6:151753470 G/C cg10883421 chr6:151773342 RMND1;C6orf211 0.61 5.97 0.47 2.29e-8 Menarche (age at onset); TGCT cis rs1799949 0.930 rs1554063 chr17:41287145 T/C cg10047753 chr17:41438598 NA 0.77 7.29 0.55 3.18e-11 Menopause (age at onset); TGCT cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs2050392 0.517 rs602097 chr10:30747546 C/T cg18806716 chr10:30721971 MAP3K8 -0.47 -5.45 -0.44 2.62e-7 Inflammatory bowel disease; TGCT cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg02353165 chr6:42928485 GNMT 0.95 9.51 0.65 1.95e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.33e-9 Electroencephalogram traits; TGCT cis rs40363 0.645 rs6501177 chr16:3523681 C/T cg21433313 chr16:3507492 NAT15 0.39 5.08 0.41 1.36e-6 Tuberculosis; TGCT cis rs11718455 0.960 rs35869565 chr3:44002394 G/C cg08738300 chr3:44038990 NA 0.85 6.41 0.5 2.72e-9 Coronary artery disease; TGCT cis rs1670533 1.000 rs7679432 chr4:1050521 G/A cg20887711 chr4:1340912 KIAA1530 0.7 5.66 0.45 9.77e-8 Recombination rate (females); TGCT cis rs639012 0.636 rs7941541 chr11:85858538 A/G cg07180834 chr11:85838833 NA 0.37 5.36 0.43 3.92e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1555895 0.576 rs4229 chr10:856918 A/T cg02193355 chr10:851439 NA 0.24 5.41 0.44 3.1e-7 Survival in rectal cancer; TGCT cis rs116095464 0.558 rs6879656 chr5:264428 T/C cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT cis rs17076896 0.655 rs74038131 chr13:19934867 C/T cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs13256369 1.000 rs13266699 chr8:8570313 A/T cg06671706 chr8:8559999 CLDN23 -0.34 -4.57 -0.38 1.18e-5 Obesity-related traits; TGCT cis rs80282103 0.764 rs10047383 chr10:1103095 A/G cg08668510 chr10:1095578 IDI1 1.01 4.51 0.38 1.48e-5 Glomerular filtration rate (creatinine); TGCT cis rs780094 0.606 rs6729709 chr2:27583156 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.33 4.5 0.37 1.57e-5 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; TGCT cis rs10851411 0.789 rs1900920 chr15:42768198 C/T cg12711755 chr15:41779622 NA -0.19 -4.73 -0.39 5.95e-6 Glucose homeostasis traits; TGCT trans rs561341 1.000 rs576985 chr17:30323323 C/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT trans rs57221529 0.766 rs4527146 chr5:555236 A/G cg11887960 chr12:57824829 NA 1.16 9.45 0.65 2.66e-16 Lung disease severity in cystic fibrosis; TGCT cis rs2070488 0.965 rs1058945 chr3:38532511 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.88 -8.99 -0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs12477438 0.501 rs13000731 chr2:99795231 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg06212747 chr3:49208901 KLHDC8B 0.71 6.63 0.51 9.48e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9549367 0.826 rs2287249 chr13:113889355 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.49 -0.44 2.18e-7 Platelet distribution width; TGCT cis rs7666738 0.830 rs10034619 chr4:98970067 G/C cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT trans rs7819412 0.837 rs17724467 chr8:10975682 C/G cg15556689 chr8:8085844 FLJ10661 -0.76 -7.24 -0.55 4.21e-11 Triglycerides; TGCT cis rs1401999 0.934 rs1132776 chr3:183696402 A/G cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs4478037 0.822 rs9827863 chr3:33118951 C/T cg19404215 chr3:33155277 CRTAP -1.28 -6.37 -0.5 3.33e-9 Major depressive disorder; TGCT cis rs9640161 0.789 rs1464751 chr7:150021282 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.62 0.38 9.64e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs17490626 0.512 rs12241097 chr10:71216678 T/G cg14388049 chr10:71211838 TSPAN15 -0.39 -4.5 -0.37 1.55e-5 Thrombosis; TGCT cis rs8014204 1.000 rs8014204 chr14:75322794 A/G cg06637938 chr14:75390232 RPS6KL1 0.75 7.09 0.54 8.97e-11 Caffeine consumption; TGCT cis rs9611565 0.921 rs5758297 chr22:41720697 A/G cg17554472 chr22:41940697 POLR3H -0.39 -4.49 -0.37 1.58e-5 Vitiligo; TGCT cis rs9911578 0.967 rs8075786 chr17:56819216 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs35883536 0.647 rs2647325 chr1:101040195 T/C cg06223162 chr1:101003688 GPR88 0.42 7.97 0.58 8.84e-13 Monocyte count; TGCT cis rs1497406 0.744 rs6690317 chr1:16516585 T/C cg20430773 chr1:16534157 ARHGEF19 0.52 6.25 0.49 6.18e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4819052 0.765 rs2838854 chr21:46680364 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs17331151 0.541 rs11709430 chr3:52862055 G/A cg27565382 chr3:53032988 SFMBT1 0.4 5.05 0.41 1.57e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9457247 0.565 rs2239824 chr6:167511799 T/A cg07741184 chr6:167504864 NA 0.29 5.6 0.45 1.34e-7 Crohn's disease; TGCT cis rs6061231 0.740 rs11698650 chr20:60958374 A/T cg24112000 chr20:60950667 NA -0.34 -5.07 -0.41 1.38e-6 Colorectal cancer; TGCT cis rs28595532 0.920 rs114789346 chr4:119748652 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9467773 1.000 rs6903973 chr6:26499942 C/A cg15659132 chr6:26577336 NA 0.84 11.93 0.73 2.59e-22 Intelligence (multi-trait analysis); TGCT cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg17747265 chr1:1875780 NA -0.38 -7.18 -0.54 5.67e-11 Body mass index; TGCT cis rs7666738 0.830 rs13133355 chr4:98919415 A/G cg17366294 chr4:99064904 C4orf37 0.71 7.25 0.55 3.96e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6484504 0.532 rs2761589 chr11:31311429 C/G cg26647111 chr11:31128758 NA 0.33 4.74 0.39 5.71e-6 Red blood cell count; TGCT cis rs35883536 0.647 rs12043865 chr1:101042651 G/A cg14855972 chr1:101004472 GPR88 -0.24 -4.49 -0.37 1.64e-5 Monocyte count; TGCT cis rs7824557 0.583 rs2736292 chr8:11234500 A/T cg21775007 chr8:11205619 TDH 0.71 7.57 0.56 7.28e-12 Retinal vascular caliber; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg15242686 chr22:24348715 GSTTP1 -0.5 -5.91 -0.47 3.07e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7666738 0.830 rs28497822 chr4:98906873 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.88 0.4 3.2e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2072499 0.966 rs2253677 chr1:156171296 C/G cg25208724 chr1:156163844 SLC25A44 -1.14 -17.15 -0.84 1.56e-34 Testicular germ cell tumor; TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg22166914 chr1:53195759 ZYG11B 0.4 6.61 0.51 1.04e-9 Monocyte count; TGCT cis rs7615952 0.932 rs1976458 chr3:125647512 T/G cg05084668 chr3:125655381 ALG1L -0.76 -6.08 -0.48 1.39e-8 Blood pressure (smoking interaction); TGCT cis rs2404602 0.679 rs12908421 chr15:76881794 T/G cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.07e-6 Blood metabolite levels; TGCT cis rs66561647 0.661 rs7835090 chr8:128940177 A/C cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.58 0.38 1.1e-5 Hemoglobin concentration; TGCT cis rs10793273 1 rs10793273 chr11:77742595 T/C cg09721595 chr11:77773924 THRSP -0.4 -6.92 -0.53 2.19e-10 Pelvic organ prolapse; TGCT cis rs7428 0.545 rs17026212 chr2:85551696 T/G cg03728395 chr2:85555865 TGOLN2 -0.29 -5.09 -0.42 1.32e-6 Ear protrusion; TGCT trans rs2727020 0.786 rs10839263 chr11:49354462 A/G cg03929089 chr4:120376271 NA -0.64 -6.74 -0.52 5.34e-10 Coronary artery disease; TGCT cis rs4664308 0.935 rs877200 chr2:160903723 G/C cg03641300 chr2:160917029 PLA2R1 -0.26 -6.52 -0.51 1.6e-9 Idiopathic membranous nephropathy; TGCT cis rs9372498 0.536 rs62424172 chr6:118777533 C/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs13082711 0.554 rs66854845 chr3:27387008 C/T cg02860705 chr3:27208620 NA 0.43 6.05 0.48 1.6e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2486012 0.850 rs246774 chr1:44299695 C/T cg12908607 chr1:44402522 ARTN -0.76 -5.68 -0.45 9.1e-8 Intelligence (multi-trait analysis); TGCT cis rs11148252 0.574 rs2038826 chr13:53280013 G/A cg00495681 chr13:53174319 NA 0.62 6.27 0.49 5.35e-9 Lewy body disease; TGCT cis rs4478858 0.684 rs7519766 chr1:31735512 C/A cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs1865760 1.000 rs56118523 chr6:25908975 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs2970818 0.831 rs2970810 chr12:4608103 A/G cg20471076 chr12:4920472 KCNA6 0.2 4.5 0.37 1.52e-5 Phosphorus levels; TGCT cis rs889312 0.500 rs702688 chr5:56190986 A/G cg12311346 chr5:56204834 C5orf35 -0.48 -5.13 -0.42 1.08e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs3015497 0.789 rs3015500 chr14:51108877 C/T cg04730355 chr14:51134070 SAV1 -0.68 -6.57 -0.51 1.26e-9 Mean platelet volume; TGCT cis rs3125734 0.633 rs6479804 chr10:64048327 T/C cg09941381 chr10:64027924 RTKN2 -0.33 -4.9 -0.4 2.94e-6 Rheumatoid arthritis; TGCT cis rs12220238 1.000 rs1908331 chr10:75885817 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs17789174 0.514 rs11548969 chr16:85126806 T/C cg02687026 chr16:85133210 FAM92B 0.22 5.18 0.42 8.66e-7 Dysphagia; TGCT cis rs11190604 0.767 rs12360395 chr10:102194074 A/T cg16005271 chr10:102321736 NA 0.46 4.69 0.39 6.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs910316 1.000 rs4899544 chr14:75546556 C/T cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs514406 0.505 rs440871 chr1:53173052 C/T cg16325326 chr1:53192061 ZYG11B 0.86 12.19 0.74 6.07e-23 Monocyte count; TGCT cis rs4704846 1.000 rs4704850 chr5:156532952 A/G cg12943317 chr5:156479607 HAVCR1 -0.34 -4.7 -0.39 6.82e-6 Blood protein levels; TGCT cis rs1008375 0.966 rs2315553 chr4:17627332 T/C cg10189774 chr4:17578691 LAP3 0.66 5.74 0.46 6.81e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg06873352 chr17:61820015 STRADA -0.54 -5.61 -0.45 1.23e-7 Prudent dietary pattern; TGCT cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs7959452 0.590 rs7968629 chr12:69782857 G/A cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs5750830 0.649 rs4821893 chr22:39797779 G/A cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs4919694 1.000 rs12261040 chr10:104665397 T/C cg04362960 chr10:104952993 NT5C2 1.02 6.9 0.53 2.41e-10 Arsenic metabolism; TGCT cis rs4851266 0.966 rs13026283 chr2:100842638 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.06 -0.41 1.48e-6 Educational attainment; TGCT cis rs854765 0.547 rs6502632 chr17:17913057 A/G cg09796270 chr17:17721594 SREBF1 0.25 5.04 0.41 1.61e-6 Total body bone mineral density; TGCT cis rs11690935 1.000 rs2138348 chr2:172558172 A/C cg13550731 chr2:172543902 DYNC1I2 1.23 12.97 0.76 7.83e-25 Schizophrenia; TGCT cis rs1018836 0.923 rs6986088 chr8:91538474 A/C cg16814680 chr8:91681699 NA -0.86 -9.72 -0.66 6.1e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7091068 0.754 rs1326224 chr10:95459267 C/T cg20715218 chr10:95462985 C10orf4 0.54 5.03 0.41 1.66e-6 Urinary tract infection frequency; TGCT cis rs1153858 1.000 rs7494956 chr15:45668565 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs6969780 0.673 rs2301721 chr7:27196113 C/T cg04317399 chr7:27170313 HOXA4 -0.44 -4.9 -0.4 2.94e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs524023 0.914 rs2360872 chr11:64353405 T/C cg07733098 chr11:64478343 NRXN2 0.31 4.62 0.38 9.53e-6 Urate levels in obese individuals; TGCT cis rs6964587 0.773 rs13236026 chr7:91885873 A/G cg17063962 chr7:91808500 NA 0.85 8.52 0.61 4.45e-14 Breast cancer; TGCT cis rs17601876 0.651 rs12907866 chr15:51545454 A/G cg19946085 chr15:51559439 CYP19A1 -0.34 -4.86 -0.4 3.5e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs3796619 0.924 rs4690209 chr4:1077575 G/A cg27284194 chr4:1044797 NA 0.46 4.45 0.37 1.85e-5 Recombination rate (males); TGCT cis rs7119038 0.818 rs11217040 chr11:118680648 C/A cg19308663 chr11:118741387 NA 0.26 5.09 0.42 1.31e-6 Sjögren's syndrome; TGCT cis rs733175 0.855 rs6853437 chr4:10005435 A/G cg00071950 chr4:10020882 SLC2A9 -0.5 -4.58 -0.38 1.13e-5 Psychosis and Alzheimer's disease; TGCT cis rs7914558 0.966 rs7921574 chr10:104840970 T/C cg04362960 chr10:104952993 NT5C2 0.6 5.32 0.43 4.64e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9467711 0.659 rs13195509 chr6:26463660 C/T cg16898833 chr6:26189333 HIST1H4D 1.26 6.03 0.48 1.77e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs910316 0.692 rs7156586 chr14:75506230 A/T cg11812906 chr14:75593930 NEK9 0.5 4.49 0.37 1.62e-5 Height; TGCT cis rs763014 0.966 rs35642938 chr16:642249 T/C cg09263875 chr16:632152 PIGQ 0.31 6.85 0.52 3.03e-10 Height; TGCT cis rs12908161 1.000 rs62021219 chr15:85256159 C/T cg11189052 chr15:85197271 WDR73 0.75 6.29 0.49 5.02e-9 Schizophrenia; TGCT cis rs922182 0.557 rs6494452 chr15:64199208 G/A cg02919090 chr15:64263738 DAPK2 0.38 7.01 0.53 1.37e-10 Blood protein levels; TGCT cis rs12620999 0.589 rs6753960 chr2:238105270 C/G cg23555395 chr2:238036564 NA -0.26 -4.45 -0.37 1.88e-5 Systemic lupus erythematosus; TGCT cis rs7584330 0.955 rs13432426 chr2:238388631 T/G cg08992911 chr2:238395768 MLPH 0.67 5.44 0.44 2.69e-7 Prostate cancer; TGCT cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs2735413 0.564 rs73580821 chr16:78110304 A/G cg09132178 chr16:78079569 NA 0.37 4.8 0.4 4.4e-6 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs35160687 0.901 rs17738096 chr2:86513893 C/G cg03171300 chr2:86307199 POLR1A 0.32 5.54 0.45 1.73e-7 Night sleep phenotypes; TGCT cis rs7666738 0.830 rs6854919 chr4:98947326 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.13 0.54 7.23e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2820315 1.000 rs2172935 chr1:201826340 A/G cg12730843 chr1:201915899 LMOD1 0.27 4.8 0.4 4.44e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs36051895 0.664 rs1034072 chr9:5088903 T/A cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs6570726 1.000 rs436066 chr6:145847127 C/T cg23711669 chr6:146136114 FBXO30 0.69 6.5 0.5 1.78e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10875595 0.779 rs4912746 chr5:140673969 T/C cg24830062 chr5:140700576 TAF7 -0.61 -5.14 -0.42 1.04e-6 Pulmonary function decline; TGCT cis rs7659604 0.502 rs10013916 chr4:122702179 T/G cg06713675 chr4:122721982 EXOSC9 0.36 4.51 0.38 1.48e-5 Type 2 diabetes; TGCT cis rs3096299 0.900 rs4785663 chr16:89434888 G/A cg02187348 chr16:89574699 SPG7 0.48 4.55 0.38 1.26e-5 Multiple myeloma (IgH translocation); TGCT trans rs62103177 0.683 rs13838 chr18:77663409 C/G cg05926928 chr17:57297772 GDPD1 1.22 10.76 0.69 1.81e-19 Opioid sensitivity; TGCT cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs478304 0.619 rs10791822 chr11:65428706 T/C cg17480646 chr11:65405466 SIPA1 -0.61 -7.88 -0.58 1.4e-12 Acne (severe); TGCT cis rs56309584 0.560 rs79224651 chr17:8076667 T/G cg08322244 chr17:8066669 VAMP2 -0.52 -4.89 -0.4 3.04e-6 Initial pursuit acceleration; TGCT cis rs2414095 0.527 rs11632036 chr15:51542162 A/C cg19946085 chr15:51559439 CYP19A1 -0.32 -4.55 -0.38 1.27e-5 Follicule stimulating hormone;Hormone measurements;Total body bone mineral density; TGCT cis rs9660992 0.710 rs4951184 chr1:205240659 A/T cg00857998 chr1:205179979 DSTYK 0.52 4.61 0.38 9.99e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs2404602 0.583 rs12592501 chr15:76554790 C/A cg22467129 chr15:76604101 ETFA -0.62 -8.06 -0.59 5.34e-13 Blood metabolite levels; TGCT cis rs921968 0.541 rs634590 chr2:219372768 C/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs35306767 0.953 rs34405399 chr10:981015 G/A cg20503657 chr10:835505 NA 0.58 8.09 0.59 4.54e-13 Eosinophil percentage of granulocytes; TGCT cis rs6831352 1.000 rs10017466 chr4:100055800 C/T cg12011299 chr4:100065546 ADH4 0.4 5.07 0.41 1.44e-6 Alcohol dependence; TGCT cis rs854765 0.520 rs9899355 chr17:17898243 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.19 0.54 5.35e-11 Total body bone mineral density; TGCT cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs9660992 0.710 rs1172111 chr1:205232980 C/T cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs72700829 0.593 rs4418603 chr1:150989274 A/G cg00666978 chr1:150947442 LASS2 0.9 4.62 0.38 9.37e-6 Schizophrenia; TGCT cis rs9425766 0.640 rs9425756 chr1:173816586 C/T cg07177756 chr1:173836307 SNORD75;SNORD78;ZBTB37;SNORD76;GAS5;SNORD77;SNORD44 0.49 4.51 0.38 1.49e-5 Life satisfaction; TGCT cis rs9381040 0.610 rs2268196 chr6:41021950 C/G cg03526776 chr6:41159608 TREML2 -0.27 -5.29 -0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs7582180 0.764 rs11693424 chr2:100925439 G/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs12681288 0.823 rs2701909 chr8:1003057 A/G cg04851639 chr8:1020857 NA -0.36 -6.47 -0.5 2.01e-9 Schizophrenia; TGCT cis rs7296418 0.885 rs1727305 chr12:123633382 T/C cg00376283 chr12:123451042 ABCB9 0.84 7.66 0.57 4.68e-12 Platelet count; TGCT cis rs1568889 0.938 rs1464898 chr11:28034748 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.87 8.85 0.62 7.64e-15 Bipolar disorder; TGCT cis rs2594989 0.895 rs439738 chr3:11322577 G/C cg00170343 chr3:11313890 ATG7 0.68 5.18 0.42 8.63e-7 Circulating chemerin levels; TGCT cis rs2153535 0.560 rs9379214 chr6:8480870 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.02 0.41 1.75e-6 Motion sickness; TGCT cis rs11098499 0.866 rs12510451 chr4:120289143 C/T cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs7582180 0.591 rs12991577 chr2:101010867 C/A cg08017756 chr2:100939284 LONRF2 -0.31 -4.87 -0.4 3.32e-6 Intelligence (multi-trait analysis); TGCT cis rs4919044 0.641 rs12357515 chr10:94725508 A/G cg05127821 chr10:94822908 CYP26C1 -0.73 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs10540 1.000 rs61876335 chr11:488878 T/C cg03352830 chr11:487213 PTDSS2 0.27 4.67 0.39 7.56e-6 Body mass index; TGCT cis rs734999 0.505 rs10910108 chr1:2539532 A/G cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs7647973 0.731 rs9831648 chr3:49214303 G/T cg05785598 chr3:49045655 WDR6 0.43 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs875971 1.000 rs7783613 chr7:65805261 C/T cg11764359 chr7:65958608 NA -0.61 -5.51 -0.44 1.96e-7 Aortic root size; TGCT cis rs1994135 0.669 rs10844629 chr12:33697096 T/A cg06521331 chr12:34319734 NA -0.3 -4.73 -0.39 6.09e-6 Resting heart rate; TGCT cis rs2760061 0.583 rs3094911 chr1:228210179 A/G cg02753203 chr1:228287806 NA 0.37 7.5 0.56 1.05e-11 Diastolic blood pressure; TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg08859206 chr1:53392774 SCP2 -0.45 -7.34 -0.55 2.5e-11 Monocyte count; TGCT trans rs208515 0.556 rs12201658 chr6:66678457 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.92 10.09 0.67 7.45e-18 Exhaled nitric oxide levels; TGCT cis rs7255045 0.665 rs2014639 chr19:12975021 G/C cg23899408 chr19:12877188 HOOK2 -0.62 -5.04 -0.41 1.58e-6 Mean corpuscular volume; TGCT cis rs4665809 0.887 rs4665814 chr2:26273687 G/T cg22920501 chr2:26401640 FAM59B -0.73 -6.32 -0.49 4.19e-9 Gut microbiome composition (summer); TGCT cis rs9611565 0.649 rs5751144 chr22:42128097 A/G cg06481639 chr22:41940642 POLR3H -0.56 -4.87 -0.4 3.39e-6 Vitiligo; TGCT cis rs7528684 0.725 rs10430455 chr1:157703238 T/A cg17134153 chr1:157670328 FCRL3 0.27 4.75 0.39 5.61e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs2204008 0.540 rs1672425 chr12:38122842 G/A cg26384229 chr12:38710491 ALG10B -0.59 -5.23 -0.42 7.06e-7 Bladder cancer; TGCT cis rs155076 0.938 rs261375 chr13:21871882 A/G cg14456004 chr13:21872349 NA 1.3 9.95 0.67 1.7e-17 White matter hyperintensity burden; TGCT cis rs12762955 0.561 rs10752022 chr10:1043798 C/T cg26597838 chr10:835615 NA -0.46 -6.1 -0.48 1.23e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs151997 0.925 rs27570 chr5:50191974 G/A cg06027927 chr5:50259733 NA 0.49 5.03 0.41 1.65e-6 Callous-unemotional behaviour; TGCT cis rs4642101 0.765 rs3901665 chr3:12824610 C/A cg05775895 chr3:12838266 CAND2 0.79 9.04 0.63 2.61e-15 QRS complex (12-leadsum); TGCT cis rs76419734 0.558 rs4324546 chr4:106526987 C/T cg24545054 chr4:106630052 GSTCD;INTS12 -0.76 -4.79 -0.39 4.76e-6 Post bronchodilator FEV1; TGCT cis rs4654899 0.758 rs12402486 chr1:21447935 A/G cg01072550 chr1:21505969 NA 0.56 9.08 0.63 2.14e-15 Superior frontal gyrus grey matter volume; TGCT cis rs2836950 0.509 rs4816618 chr21:40599529 G/A cg11890956 chr21:40555474 PSMG1 -0.7 -6.87 -0.52 2.79e-10 Menarche (age at onset); TGCT cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg16497277 chr3:49208875 KLHDC8B -0.59 -5.59 -0.45 1.4e-7 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT trans rs877282 0.853 rs11253332 chr10:755262 G/C cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs2404602 0.692 rs35395069 chr15:76986334 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs9811920 0.529 rs793442 chr3:99581062 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.61 6.99 0.53 1.47e-10 Axial length; TGCT cis rs748404 0.631 rs6493086 chr15:43655394 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT trans rs1814175 0.817 rs10839351 chr11:49758153 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.44 -0.56 1.47e-11 Height; TGCT cis rs4851266 0.901 rs4851271 chr2:100833058 T/C cg07810366 chr2:100720526 AFF3 -0.37 -5.33 -0.43 4.53e-7 Educational attainment; TGCT cis rs12220238 1.000 rs7907801 chr10:75976638 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4566357 1.000 rs2141829 chr2:227922454 G/A cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs9419702 0.568 rs7093241 chr10:133556596 G/A cg04492858 chr10:133558786 NA 0.56 5.96 0.47 2.46e-8 Survival in rectal cancer; TGCT cis rs10940138 0.720 rs2372188 chr5:67233704 T/C ch.5.1281357F chr5:67228439 NA 0.38 4.56 0.38 1.2e-5 Menarche (age at onset); TGCT cis rs782590 0.902 rs782602 chr2:55849309 A/G cg18811423 chr2:55921094 PNPT1 0.63 6.6 0.51 1.05e-9 Metabolic syndrome; TGCT cis rs10883723 0.518 rs10786679 chr10:104315667 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.72 6.14 0.48 1.02e-8 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4654899 0.601 rs6668094 chr1:21464387 C/T cg01072550 chr1:21505969 NA 0.56 9.18 0.64 1.2e-15 Superior frontal gyrus grey matter volume; TGCT cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg03188948 chr7:1209495 NA 0.59 4.8 0.4 4.51e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7647973 1.000 rs10865956 chr3:49581559 C/A cg06212747 chr3:49208901 KLHDC8B 0.54 4.45 0.37 1.87e-5 Menarche (age at onset); TGCT cis rs1215050 0.740 rs1084784 chr4:98961711 T/G cg05340658 chr4:99064831 C4orf37 -0.44 -5.35 -0.43 4.13e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4319547 0.656 rs7135419 chr12:122911861 T/A cg05707623 chr12:122985044 ZCCHC8 -0.65 -5.07 -0.41 1.39e-6 Body mass index; TGCT cis rs10875746 0.855 rs12296244 chr12:48441479 C/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg12419862 chr22:24373484 LOC391322 -0.8 -8.67 -0.61 1.97e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2074585 0.806 rs2657949 chr15:90950790 G/A cg22089800 chr15:90895588 ZNF774 0.78 8.09 0.59 4.55e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs3820068 0.544 rs7551750 chr1:16035008 T/C cg17385448 chr1:15911702 AGMAT 0.35 4.99 0.41 1.96e-6 Systolic blood pressure; TGCT cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg04944784 chr2:26401820 FAM59B -0.76 -6.34 -0.49 3.94e-9 Gut microbiome composition (summer); TGCT cis rs9788721 0.902 rs114205691 chr15:78901113 C/T cg18825076 chr15:78729989 IREB2 -0.29 -4.45 -0.37 1.88e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs45509595 0.841 rs200501 chr6:27788942 C/T cg10876282 chr6:28092338 ZSCAN16 0.78 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs2204008 0.837 rs11168387 chr12:37962818 G/A cg26384229 chr12:38710491 ALG10B -0.7 -6.12 -0.48 1.11e-8 Bladder cancer; TGCT cis rs5769765 0.862 rs138856 chr22:50199378 G/T cg15316289 chr22:50310904 ALG12;CRELD2 0.36 5.26 0.43 6.2e-7 Schizophrenia; TGCT cis rs113507773 1 rs113507773 chr6:26255739 G/A cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.68 -4.45 -0.37 1.89e-5 Iron status biomarkers (transferrin saturation);Iron status biomarkers (iron levels); TGCT cis rs10464366 0.560 rs12672089 chr7:39132816 G/A cg18850127 chr7:39170497 POU6F2 0.28 6.39 0.5 3.1e-9 IgG glycosylation; TGCT cis rs8017423 0.967 rs59006192 chr14:90706456 C/T cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs9916302 0.861 rs10491129 chr17:37461643 T/G cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs10858047 0.883 rs41274118 chr1:115119392 T/C cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs7945705 0.967 rs7123429 chr11:8866808 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -5.2 -0.42 8.12e-7 Hemoglobin concentration; TGCT cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.94 -6.05 -0.48 1.59e-8 Alzheimer's disease; TGCT cis rs17331151 0.573 rs13080929 chr3:52885112 A/C cg12962167 chr3:53033115 SFMBT1 0.42 4.62 0.38 9.36e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3733585 0.657 rs62286568 chr4:10124889 C/T cg00071950 chr4:10020882 SLC2A9 -0.48 -4.96 -0.41 2.25e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6952808 0.531 rs3779002 chr7:2183219 C/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.66 -0.39 8.13e-6 Bipolar disorder and schizophrenia; TGCT cis rs7666738 0.680 rs34267968 chr4:99002574 A/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs732765 1.000 rs3742785 chr14:75373034 A/C cg06637938 chr14:75390232 RPS6KL1 -0.62 -5.37 -0.43 3.7e-7 Non-small cell lung cancer; TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs7147624 1.000 rs1009465 chr14:65970370 G/C cg03016385 chr14:66212404 NA -0.49 -7.11 -0.54 8.13e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2580764 0.598 rs6726158 chr2:55239202 G/T cg09592903 chr2:55203963 RTN4 -0.27 -6.12 -0.48 1.15e-8 Mean platelet volume; TGCT cis rs9467711 0.606 rs9358936 chr6:26370657 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7043114 0.525 rs7047089 chr9:95117980 C/T cg14631576 chr9:95140430 CENPP -0.27 -4.45 -0.37 1.87e-5 Height; TGCT cis rs7582180 0.563 rs4851304 chr2:100963871 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs9388451 0.626 rs1935983 chr6:126068914 C/T cg10911889 chr6:126070802 HEY2 0.5 4.69 0.39 7.17e-6 Brugada syndrome; TGCT cis rs10871290 1.000 rs11149710 chr16:74472546 G/T cg01733217 chr16:74700730 RFWD3 -0.52 -4.78 -0.39 4.78e-6 Breast cancer; TGCT cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg02458000 chr6:26745757 NA 0.52 4.8 0.4 4.48e-6 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.772 rs1976559 chr1:154879788 A/T cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs7089973 0.624 rs11196940 chr10:116593791 T/G cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs3806843 0.576 rs155363 chr5:140301543 A/G cg07102913 chr5:140593443 PCDHB13 -0.48 -4.77 -0.39 5.15e-6 Depressive symptoms (multi-trait analysis); TGCT trans rs11088226 0.645 rs2409457 chr21:33929895 T/C cg09050820 chr6:167586206 TCP10L2 0.76 6.79 0.52 4.22e-10 Gastritis; TGCT cis rs9928842 0.823 rs2870472 chr16:75278841 C/G cg09066997 chr16:75300724 BCAR1 0.26 4.67 0.39 7.84e-6 Alcoholic chronic pancreatitis; TGCT cis rs7226408 0.842 rs9958203 chr18:34348958 A/G cg06757138 chr18:34340585 FHOD3 0.29 5.15 0.42 1.01e-6 Obesity-related traits; TGCT cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg23758822 chr17:41437982 NA 0.72 6.89 0.53 2.46e-10 Menopause (age at onset); TGCT cis rs9993613 0.875 rs6841091 chr4:73459531 C/G cg15102770 chr4:73434591 ADAMTS3 -0.51 -4.8 -0.4 4.47e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs4788570 0.615 rs889568 chr16:71772399 T/C cg06353428 chr16:71660113 MARVELD3 1.54 12.41 0.74 1.74e-23 Intelligence (multi-trait analysis); TGCT cis rs1670533 0.615 rs59985183 chr4:1087171 G/T cg20887711 chr4:1340912 KIAA1530 0.62 4.93 0.41 2.53e-6 Recombination rate (females); TGCT cis rs597539 0.652 rs507520 chr11:68666054 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.22 0.59 2.35e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs71636778 0.509 rs11555809 chr1:27216669 G/A cg23921621 chr1:27994728 IFI6 -0.42 -4.59 -0.38 1.06e-5 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs1005277 0.563 rs2505215 chr10:38481273 A/G cg25427524 chr10:38739819 LOC399744 -0.41 -8.54 -0.61 4.04e-14 Extrinsic epigenetic age acceleration; TGCT cis rs12681287 0.752 rs4389908 chr8:87274852 A/G cg27223183 chr8:87520930 FAM82B -0.82 -5.86 -0.47 3.98e-8 Caudate activity during reward; TGCT cis rs12210905 0.688 rs114843651 chr6:27449611 A/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs155076 1.000 rs566364 chr13:21837583 T/C cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs1372520 0.684 rs2619356 chr4:90750844 C/T cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs9308731 0.688 rs4302219 chr2:111880284 G/T cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.1e-9 Chronic lymphocytic leukemia; TGCT cis rs9948 0.655 rs6751132 chr2:97405866 T/C cg01990225 chr2:97406019 LMAN2L -0.9 -5.35 -0.43 4.05e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs12971120 0.838 rs3794950 chr18:72182965 G/A cg25817165 chr18:72167213 CNDP2 -0.27 -4.65 -0.39 8.46e-6 Refractive error; TGCT cis rs67478160 0.643 rs34813623 chr14:104263294 A/G cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs4727027 0.933 rs1058059 chr7:148879134 A/T cg23583168 chr7:148888333 NA -0.74 -9.81 -0.66 3.64e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6674176 0.597 rs6671164 chr1:44403489 G/T cg12908607 chr1:44402522 ARTN -0.73 -8.91 -0.62 5.24e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT trans rs9467711 1.000 rs6939978 chr6:26328462 G/C cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs7582180 0.629 rs11688285 chr2:100948054 A/C cg14675211 chr2:100938903 LONRF2 0.5 4.73 0.39 5.96e-6 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.783 rs1994970 chr17:47014127 C/T cg00947319 chr17:47005597 UBE2Z 0.2 4.74 0.39 5.83e-6 Type 2 diabetes; TGCT cis rs854765 0.663 rs16960744 chr17:17755259 A/G cg09796270 chr17:17721594 SREBF1 -0.26 -4.93 -0.4 2.59e-6 Total body bone mineral density; TGCT cis rs644799 0.710 rs523153 chr11:95570961 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.79 7.88 0.58 1.41e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs57221529 0.766 rs12522303 chr5:555564 A/C cg09021430 chr5:549028 NA -0.4 -5.46 -0.44 2.44e-7 Lung disease severity in cystic fibrosis; TGCT cis rs763121 0.962 rs5757135 chr22:38952573 C/T cg06022373 chr22:39101656 GTPBP1 0.74 7.2 0.54 5.19e-11 Menopause (age at onset); TGCT cis rs1532993 0.500 rs2085324 chr4:98621066 T/C cg05340658 chr4:99064831 C4orf37 -0.37 -4.44 -0.37 1.98e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg11644478 chr21:40555479 PSMG1 -0.53 -4.97 -0.41 2.14e-6 Menarche (age at onset); TGCT cis rs6545883 0.894 rs778143 chr2:61581890 A/C cg15711740 chr2:61764176 XPO1 -0.54 -4.74 -0.39 5.82e-6 Tuberculosis; TGCT cis rs763014 1.000 rs2269558 chr16:682250 C/T cg00908189 chr16:619842 PIGQ 0.86 10.48 0.69 8.48e-19 Height; TGCT cis rs10779751 0.770 rs11585553 chr1:11233814 G/A cg08854313 chr1:11322531 MTOR -0.83 -6.46 -0.5 2.16e-9 Body mass index; TGCT cis rs7772486 0.790 rs2265474 chr6:146182092 G/A cg23711669 chr6:146136114 FBXO30 0.96 11.32 0.71 7.81e-21 Lobe attachment (rater-scored or self-reported); TGCT cis rs4713118 0.525 rs9357042 chr6:27582795 A/C cg10876282 chr6:28092338 ZSCAN16 0.45 4.61 0.38 9.84e-6 Parkinson's disease; TGCT trans rs66573146 1.000 rs55672215 chr4:6970529 T/C cg07817883 chr1:32538562 TMEM39B 1.37 7.77 0.57 2.56e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs6089584 0.606 rs7270469 chr20:60577258 G/A cg13770153 chr20:60521292 NA -0.41 -5.12 -0.42 1.16e-6 Body mass index; TGCT cis rs317689 0.718 rs315130 chr12:69761444 T/C cg20891283 chr12:69753455 YEATS4 0.55 4.5 0.37 1.53e-5 Response to diuretic therapy; TGCT cis rs709400 1.000 rs2403205 chr14:104143385 C/T cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs78487399 0.710 rs6743071 chr2:43586287 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.46 -5.22 -0.42 7.39e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.58 -5.86 -0.47 3.93e-8 Intelligence (multi-trait analysis); TGCT cis rs12049351 0.665 rs3738186 chr1:229657230 A/C cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs13256369 0.802 rs11249883 chr8:8561537 G/A cg17143192 chr8:8559678 CLDN23 0.54 5.03 0.41 1.64e-6 Obesity-related traits; TGCT cis rs617219 0.726 rs1962002 chr5:78430689 T/C cg23514016 chr5:78407564 BHMT 0.33 4.96 0.41 2.31e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs13242816 1.000 rs56010123 chr7:116173046 C/T cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg12311346 chr5:56204834 C5orf35 -0.63 -6.53 -0.51 1.51e-9 Initial pursuit acceleration; TGCT cis rs7904368 0.568 rs10752061 chr10:16853900 A/G cg23933602 chr10:16859644 RSU1 0.6 5.31 0.43 4.83e-7 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs6484504 0.576 rs176373 chr11:31136026 G/T cg26647111 chr11:31128758 NA -0.33 -4.69 -0.39 6.96e-6 Red blood cell count; TGCT cis rs7829975 0.777 rs486781 chr8:8639740 A/G cg08975724 chr8:8085496 FLJ10661 -0.52 -4.51 -0.38 1.47e-5 Mood instability; TGCT cis rs4654899 0.865 rs957163 chr1:21416181 G/T cg01072550 chr1:21505969 NA -0.47 -7.1 -0.54 8.54e-11 Superior frontal gyrus grey matter volume; TGCT cis rs6570726 0.935 rs421690 chr6:145834594 A/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3733585 0.673 rs7378340 chr4:9955198 C/T cg11266682 chr4:10021025 SLC2A9 -0.59 -7.81 -0.57 2.04e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4253772 0.530 rs6008662 chr22:46713917 G/A cg26492175 chr22:47022658 GRAMD4 0.2 4.47 0.37 1.72e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs10479542 0.896 rs10078712 chr5:178978805 C/T cg09060608 chr5:178986726 RUFY1 -0.48 -5.33 -0.43 4.42e-7 Lung cancer; TGCT cis rs17376456 0.825 rs6898842 chr5:93213221 T/C cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.17e-13 Diabetic retinopathy; TGCT cis rs864537 0.676 rs2056625 chr1:167420299 G/A cg22356347 chr1:167427500 CD247 -0.21 -5.21 -0.42 7.58e-7 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs7044106 0.791 rs735109 chr9:123488879 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 7.23 0.54 4.43e-11 Hip circumference adjusted for BMI; TGCT cis rs12048904 0.505 rs11166511 chr1:101240686 G/C cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.81 -6.9 -0.53 2.4e-10 Multiple sclerosis; TGCT cis rs270601 0.913 rs273899 chr5:131695178 G/A cg24060327 chr5:131705240 SLC22A5 -0.77 -8.46 -0.6 6.27e-14 Acylcarnitine levels; TGCT cis rs68170813 0.559 rs60255281 chr7:106963913 C/T cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.43e-8 Coronary artery disease; TGCT cis rs4455778 0.626 rs1558307 chr7:49030540 A/C cg26309511 chr7:48887640 NA 0.44 5.22 0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs9393692 0.875 rs6939589 chr6:26289203 C/T cg13736514 chr6:26305472 NA 0.4 5.64 0.45 1.1e-7 Educational attainment; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg15383120 chr6:291909 DUSP22 0.65 6.92 0.53 2.11e-10 Menopause (age at onset); TGCT cis rs875971 0.564 rs313804 chr7:65514622 A/G cg18876405 chr7:65276391 NA 0.33 4.95 0.41 2.39e-6 Aortic root size; TGCT cis rs11190604 1.000 rs79831012 chr10:102237059 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs35883536 0.647 rs2783696 chr1:101044089 G/A cg10298815 chr1:101004474 GPR88 0.24 4.44 0.37 1.95e-5 Monocyte count; TGCT cis rs514406 0.825 rs6695819 chr1:53223366 T/C cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.41 2.55e-6 Monocyte count; TGCT cis rs751728 0.687 rs943471 chr6:33738314 C/T cg13859433 chr6:33739653 LEMD2 -0.32 -5.6 -0.45 1.29e-7 Crohn's disease; TGCT cis rs2153535 0.580 rs9379215 chr6:8481225 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg09060608 chr5:178986726 RUFY1 0.63 8.01 0.58 7.23e-13 Lung cancer; TGCT cis rs8020441 0.838 rs4901051 chr14:51164768 G/A cg04730355 chr14:51134070 SAV1 0.71 5.84 0.46 4.39e-8 Cognitive performance; TGCT cis rs2439831 0.867 rs3101443 chr15:43912372 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.93 6.64 0.51 8.7e-10 Lung cancer in ever smokers; TGCT cis rs1371867 0.846 rs1660348 chr8:101315248 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs68170813 0.559 rs10953534 chr7:106913718 A/G cg02696742 chr7:106810147 HBP1 0.73 6.11 0.48 1.18e-8 Coronary artery disease; TGCT cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT cis rs1865760 0.622 rs10946807 chr6:26079638 T/C cg17691542 chr6:26056736 HIST1H1C 0.71 5.47 0.44 2.34e-7 Height; TGCT cis rs7772486 0.738 rs2246334 chr6:146183635 G/A cg23711669 chr6:146136114 FBXO30 0.95 10.95 0.7 6.09e-20 Lobe attachment (rater-scored or self-reported); TGCT trans rs12599106 0.792 rs12597352 chr16:34638507 A/T cg11235426 chr6:292522 DUSP22 -0.64 -6.71 -0.52 6.09e-10 Menopause (age at onset); TGCT cis rs6684514 1.000 rs12040868 chr1:156284803 G/T cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4808199 0.947 rs2163804 chr19:19575965 G/A cg03709012 chr19:19516395 GATAD2A 1.02 7.83 0.58 1.82e-12 Nonalcoholic fatty liver disease; TGCT cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg03806693 chr22:41940476 POLR3H 1.04 10.57 0.69 5.2e-19 Vitiligo; TGCT cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg05315796 chr3:52349193 DNAH1 0.18 4.47 0.37 1.75e-5 Bipolar disorder; TGCT cis rs56399783 0.901 rs56007918 chr7:2826205 A/G cg19731401 chr7:2775893 GNA12 0.37 5.15 0.42 1e-6 Childhood ear infection; TGCT cis rs16867321 0.627 rs73023570 chr2:181510582 C/A cg23363182 chr2:181467187 NA -0.45 -4.64 -0.38 8.67e-6 Obesity; TGCT cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg12310025 chr6:25882481 NA -0.66 -5.99 -0.47 2.11e-8 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.542 rs6556833 chr5:93104707 T/C cg21475434 chr5:93447410 FAM172A 0.64 6.04 0.48 1.69e-8 Diabetic retinopathy; TGCT trans rs72772090 0.708 rs17082200 chr5:96048604 T/C cg17670890 chr5:176011783 PCDH24 0.37 6.62 0.51 9.8e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs3806843 0.548 rs246056 chr5:140325600 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.42 -5.37 -0.43 3.69e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs1577917 0.771 rs4145082 chr6:86352016 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT trans rs3780486 0.846 rs73484568 chr9:33132492 G/A cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs35306767 0.671 rs11253473 chr10:906826 A/G cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs4285028 0.948 rs35737776 chr3:121677856 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg08736216 chr1:53307985 ZYG11A -0.26 -5.27 -0.43 5.72e-7 Monocyte count; TGCT cis rs35306767 0.903 rs7914758 chr10:891702 T/C cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs7017914 0.905 rs3110248 chr8:71934935 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs9611565 0.559 rs7290990 chr22:41964357 C/A cg06481639 chr22:41940642 POLR3H -0.67 -5.71 -0.46 7.87e-8 Vitiligo; TGCT cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.55 0.51 1.37e-9 Electroencephalogram traits; TGCT cis rs1519814 0.654 rs1543201 chr8:121018888 A/T cg22335954 chr8:121166405 COL14A1 0.39 4.81 0.4 4.22e-6 Breast cancer; TGCT cis rs1843834 0.505 rs2140508 chr2:225355839 G/T cg12698349 chr2:225449008 CUL3 0.77 6.28 0.49 5.2e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.91 0.4 2.83e-6 Height; TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 4.98 0.41 2.08e-6 Prudent dietary pattern; TGCT cis rs7439150 1.000 rs4508864 chr4:155481289 C/T cg22130008 chr4:155548532 NA -0.4 -5.08 -0.42 1.32e-6 Fibrinogen levels; TGCT cis rs6589563 0.737 rs61905086 chr11:116614863 T/C cg20660624 chr11:117307972 DSCAML1 -0.34 -4.58 -0.38 1.13e-5 Eosinophil counts; TGCT cis rs782590 0.807 rs782642 chr2:55928444 G/T cg18811423 chr2:55921094 PNPT1 0.68 7.19 0.54 5.25e-11 Metabolic syndrome; TGCT cis rs12039431 0.706 rs61776179 chr1:37986804 G/T cg17933807 chr1:38061675 GNL2 -0.81 -7.8 -0.57 2.19e-12 Epithelial ovarian cancer; TGCT cis rs514406 0.621 rs1930306 chr1:53195686 C/G cg24675658 chr1:53192096 ZYG11B 0.84 10.45 0.68 1.03e-18 Monocyte count; TGCT cis rs477895 0.713 rs11600867 chr11:63972052 T/A cg04317338 chr11:64019027 PLCB3 0.8 6.61 0.51 1.01e-9 Mean platelet volume; TGCT cis rs12142240 0.698 rs9661240 chr1:46827050 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs11122272 0.735 rs2572254 chr1:231512593 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.11 -0.54 8.07e-11 Hemoglobin concentration; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg24846343 chr22:24311635 DDTL 0.23 5.79 0.46 5.54e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs854765 0.547 rs12150369 chr17:17911014 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.4 0.6 8.61e-14 Total body bone mineral density; TGCT cis rs6912958 1.000 rs9294380 chr6:88152667 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.6 -5.84 -0.46 4.27e-8 Monocyte percentage of white cells; TGCT cis rs7072216 0.655 rs3830024 chr10:100176106 G/A cg26618903 chr10:100175079 PYROXD2 -0.42 -4.44 -0.37 1.93e-5 Metabolite levels; TGCT cis rs8177253 1.000 rs8177261 chr3:133480588 A/C cg01448562 chr3:133502909 NA -0.33 -6.71 -0.52 6.3e-10 Iron status biomarkers; TGCT trans rs10506458 0.834 rs17738403 chr12:63389200 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.54 -0.56 8.62e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs10032931 0.743 rs1385668 chr4:96459330 A/G cg03008707 chr4:96468962 UNC5C -0.38 -5.13 -0.42 1.08e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs9811920 0.809 rs923472 chr3:99758029 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.02 0.41 1.79e-6 Axial length; TGCT cis rs2777491 0.872 rs7176588 chr15:41588872 C/T cg18705301 chr15:41695430 NDUFAF1 -0.73 -10.55 -0.69 5.9e-19 Ulcerative colitis; TGCT cis rs7523273 0.565 rs1998539 chr1:207886596 G/A cg22525895 chr1:207977042 MIR29B2 0.35 5.62 0.45 1.19e-7 Schizophrenia; TGCT cis rs7666738 0.571 rs7683769 chr4:99091742 T/C cg17366294 chr4:99064904 C4orf37 0.58 5.38 0.43 3.6e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11690935 0.632 rs6723259 chr2:172622527 A/C cg13550731 chr2:172543902 DYNC1I2 0.68 6.0 0.47 2.02e-8 Schizophrenia; TGCT cis rs7639513 0.767 rs9861472 chr3:12707776 A/T cg23032965 chr3:12705835 RAF1 -0.76 -8.34 -0.6 1.18e-13 Itch intensity from mosquito bite; TGCT cis rs6964587 0.967 rs13233496 chr7:91813035 T/C cg17063962 chr7:91808500 NA 0.92 9.92 0.67 2e-17 Breast cancer; TGCT cis rs1801251 0.963 rs66549961 chr2:233602293 A/G cg25237894 chr2:233734115 C2orf82 0.32 5.72 0.46 7.51e-8 Coronary artery disease; TGCT cis rs8177253 0.965 rs3811658 chr3:133476852 C/T cg01448562 chr3:133502909 NA -0.32 -6.31 -0.49 4.57e-9 Iron status biomarkers; TGCT cis rs35306767 0.715 rs11253539 chr10:1011347 G/A cg20503657 chr10:835505 NA 0.57 6.33 0.49 4.06e-9 Eosinophil percentage of granulocytes; TGCT cis rs9911578 1.000 rs1057068 chr17:56598439 T/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.3 -0.64 6.22e-16 Intelligence (multi-trait analysis); TGCT trans rs208520 0.690 rs12202401 chr6:66760544 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs3806843 0.576 rs246008 chr5:140338485 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7267979 1.000 rs6050599 chr20:25400240 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs910316 0.967 rs7146523 chr14:75659880 T/C cg08847533 chr14:75593920 NEK9 -0.94 -10.1 -0.67 7.14e-18 Height; TGCT cis rs4645881 0.683 rs2387583 chr19:49461305 C/T cg15040422 chr19:49955266 ALDH16A1;PIH1D1 -0.83 -4.54 -0.38 1.31e-5 Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil counts; TGCT cis rs9399135 0.636 rs7749106 chr6:135268142 G/A cg24558204 chr6:135376177 HBS1L 0.51 5.43 0.44 2.86e-7 Red blood cell count; TGCT cis rs7267979 0.702 rs449801 chr20:25491847 C/T cg03522245 chr20:25566470 NINL 0.53 5.42 0.44 3.01e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7605378 0.528 rs281767 chr2:200823281 C/A cg17644776 chr2:200775616 C2orf69 0.32 7.16 0.54 6.12e-11 Osteoporosis; TGCT cis rs7666738 0.791 rs7658177 chr4:99035192 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs6867032 0.695 rs3902820 chr5:2000330 T/A cg26168224 chr5:2018326 NA -0.37 -5.73 -0.46 7.28e-8 Gut microbiome composition (winter); TGCT cis rs4665809 0.878 rs6748745 chr2:26364190 C/T cg25036284 chr2:26402008 FAM59B -0.55 -4.68 -0.39 7.51e-6 Gut microbiome composition (summer); TGCT cis rs3935685 1.000 rs62007780 chr15:78025464 G/T cg03457338 chr15:78040120 NA -0.23 -5.38 -0.43 3.65e-7 Intelligence (multi-trait analysis); TGCT cis rs4950928 0.823 rs946262 chr1:203158229 C/T cg17014757 chr1:203156097 CHI3L1 0.38 4.85 0.4 3.65e-6 YKL-40 levels; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg15383120 chr6:291909 DUSP22 -0.67 -7.01 -0.53 1.38e-10 Menopause (age at onset); TGCT cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs1048238 0.846 rs945422 chr1:16345619 T/C cg22431228 chr1:16359049 CLCNKA -0.29 -6.26 -0.49 5.66e-9 Systolic blood pressure; TGCT cis rs13191362 1.000 rs34052221 chr6:163160803 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.96 7.62 0.56 5.6e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6969780 0.915 rs3807597 chr7:27189195 C/T cg04321618 chr7:27170880 HOXA4 -0.52 -4.5 -0.38 1.51e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs10876993 0.890 rs1585781 chr12:58056701 T/G cg15848620 chr12:58087721 OS9 -0.72 -5.86 -0.47 3.91e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs9341808 0.558 rs3805911 chr6:80933996 A/C cg08355045 chr6:80787529 NA 0.3 4.83 0.4 3.92e-6 Sitting height ratio; TGCT cis rs12780845 0.540 rs2273734 chr10:17216556 C/T cg01003015 chr10:17271136 VIM 0.56 4.87 0.4 3.36e-6 Homocysteine levels; TGCT cis rs8177179 0.565 rs4355280 chr3:133468425 A/G cg24879335 chr3:133465180 TF 0.34 4.5 0.37 1.57e-5 Iron status biomarkers (transferrin levels); TGCT cis rs225245 0.765 rs226428 chr17:34049950 C/T cg05299278 chr17:33885742 SLFN14 -0.22 -4.68 -0.39 7.54e-6 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs9368481 0.678 rs62402024 chr6:26923976 T/C cg02458000 chr6:26745757 NA 0.6 5.33 0.43 4.42e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg10295955 chr4:187884368 NA 1.03 15.89 0.82 1.07e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs13394619 0.605 rs12476319 chr2:11748406 A/G cg07314298 chr2:11723111 GREB1 0.28 4.59 0.38 1.07e-5 Endometriosis; TGCT cis rs17376456 0.825 rs55947981 chr5:93278104 G/T cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs9420907 0.579 rs35623220 chr10:105631657 C/T cg26719024 chr10:105156444 PDCD11;USMG5 -0.85 -4.66 -0.39 8.08e-6 Telomere length; TGCT cis rs9677476 0.516 rs2303351 chr2:232030510 C/A cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs9910055 0.664 rs433610 chr17:42197281 A/G cg13607699 chr17:42295918 UBTF -0.81 -7.58 -0.56 7.17e-12 Total body bone mineral density; TGCT cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs4851254 0.660 rs9784000 chr2:100697201 G/C cg22139774 chr2:100720529 AFF3 -0.41 -4.47 -0.37 1.72e-5 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs763014 0.865 rs8909 chr16:633851 T/C cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs13082711 0.555 rs73149363 chr3:27265394 C/A cg02860705 chr3:27208620 NA 0.48 7.64 0.57 5.02e-12 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg13732083 chr21:47605072 C21orf56 -0.35 -4.51 -0.38 1.5e-5 Testicular germ cell tumor; TGCT cis rs1903068 1.000 rs4516787 chr4:56010165 C/T cg16572876 chr4:56024045 NA -0.44 -5.15 -0.42 9.86e-7 Endometriosis; TGCT cis rs6964587 0.839 rs62466809 chr7:91472801 A/G cg17063962 chr7:91808500 NA 0.82 8.45 0.6 6.64e-14 Breast cancer; TGCT cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg11890956 chr21:40555474 PSMG1 1.11 12.75 0.75 2.6e-24 Cognitive function; TGCT cis rs2153535 0.580 rs1832100 chr6:8446956 G/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs7659604 0.539 rs7686084 chr4:122764725 A/C cg20573242 chr4:122745356 CCNA2 0.64 5.62 0.45 1.22e-7 Type 2 diabetes; TGCT cis rs2243480 1.000 rs778691 chr7:65873092 G/C cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs597480 0.892 rs550404 chr11:85435730 C/T cg11817631 chr11:85522609 SYTL2 -0.47 -4.64 -0.38 8.67e-6 Drug-induced liver injury (nonsteroidal anti-inflammatory drugs); TGCT cis rs12681287 0.640 rs13267782 chr8:87481887 G/T cg27223183 chr8:87520930 FAM82B -0.91 -6.52 -0.51 1.64e-9 Caudate activity during reward; TGCT cis rs34734847 0.933 rs11065202 chr12:121112429 T/C cg21892295 chr12:121157589 UNC119B -0.22 -5.31 -0.43 4.79e-7 Mean corpuscular volume; TGCT cis rs933688 1.000 rs7715402 chr5:90679504 T/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.07 10.05 0.67 9.51e-18 Smoking behavior; TGCT cis rs295140 0.805 rs11890234 chr2:201206706 C/T cg04283868 chr2:201171347 SPATS2L 0.58 5.84 0.46 4.27e-8 QT interval; TGCT cis rs13242816 1.000 rs3801993 chr7:116190382 C/G cg02799643 chr7:116139180 CAV2 -0.45 -5.55 -0.45 1.66e-7 P wave duration; TGCT cis rs6121246 0.529 rs6060210 chr20:30187681 C/T cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs2404602 0.692 rs7169663 chr15:77192843 A/C cg26408565 chr15:76604113 ETFA -0.36 -4.68 -0.39 7.39e-6 Blood metabolite levels; TGCT cis rs2439831 0.867 rs2447208 chr15:43933895 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.61 0.51 1.03e-9 Lung cancer in ever smokers; TGCT cis rs7666738 0.830 rs2019163 chr4:99022747 C/T cg18180107 chr4:99064573 C4orf37 0.54 4.96 0.41 2.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4794202 0.534 rs9897598 chr17:45923496 G/A cg02219949 chr17:45927392 SP6 0.37 4.44 0.37 1.97e-5 Alzheimer's disease (cognitive decline); TGCT cis rs7666738 0.753 rs13111199 chr4:98953705 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs76878669 0.561 rs4930178 chr11:66129442 C/G cg18002602 chr11:66138449 SLC29A2 0.54 6.62 0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs7568458 0.684 rs6731700 chr2:85760991 C/G cg17127132 chr2:85788382 GGCX 0.51 4.58 0.38 1.12e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs57590327 0.508 rs7621968 chr3:81951460 A/G cg07356753 chr3:81810745 GBE1 -0.71 -6.65 -0.51 8.31e-10 Extraversion; TGCT cis rs1568889 1.000 rs7934085 chr11:28369660 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.8 7.92 0.58 1.13e-12 Bipolar disorder; TGCT cis rs933688 0.938 rs7705465 chr5:90680949 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.91e-14 Smoking behavior; TGCT cis rs1670533 1.000 rs7660779 chr4:1075940 A/G cg27284194 chr4:1044797 NA 0.69 5.94 0.47 2.69e-8 Recombination rate (females); TGCT cis rs10851411 1.000 rs10851411 chr15:42859235 T/G cg23803468 chr15:43513504 EPB42 -0.23 -4.44 -0.37 1.93e-5 Glucose homeostasis traits; TGCT cis rs2412819 0.599 rs2470120 chr15:43929070 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 4.5 0.37 1.54e-5 Lung cancer; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg03395511 chr6:291903 DUSP22 0.66 6.9 0.53 2.32e-10 Menopause (age at onset); TGCT cis rs7552404 0.731 rs11161836 chr1:76354333 C/T cg22875332 chr1:76189707 ACADM 0.67 6.71 0.52 6.12e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11190604 1.000 rs74650218 chr10:102293830 C/T cg23241863 chr10:102295624 HIF1AN 0.67 5.12 0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs79387448 0.655 rs17639215 chr2:102953444 G/A cg09003973 chr2:102972529 NA 1.38 9.42 0.65 3.27e-16 Gut microbiota (bacterial taxa); TGCT cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Vitiligo; TGCT cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.56 5.14 0.42 1.03e-6 Height; TGCT cis rs12510870 0.599 rs16849656 chr4:74450420 T/C cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs1218582 0.772 rs11264282 chr1:154867370 G/A cg24250549 chr1:154909240 PMVK 0.65 6.41 0.5 2.77e-9 Prostate cancer; TGCT cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg16414030 chr3:133502952 NA -0.5 -6.8 -0.52 3.91e-10 Iron status biomarkers; TGCT cis rs8177253 0.509 rs6762415 chr3:133478557 T/G cg11941060 chr3:133502564 NA -0.29 -5.35 -0.43 4.1e-7 Iron status biomarkers; TGCT cis rs1577917 0.958 rs11758508 chr6:86506878 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.59 4.9 0.4 2.96e-6 Response to antipsychotic treatment; TGCT cis rs912057 0.671 rs1294435 chr6:6745455 G/A cg06612196 chr6:6737390 NA 0.47 6.63 0.51 9.47e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs16867321 0.950 rs12477283 chr2:181501355 G/T cg23363182 chr2:181467187 NA -0.38 -5.55 -0.45 1.62e-7 Obesity; TGCT cis rs2073300 1.000 rs74273799 chr20:23444492 T/C cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs62103177 0.810 rs3902996 chr18:77630571 A/G cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs157350 0.608 rs157334 chr5:156117431 T/A cg19020398 chr5:156886415 NIPAL4 0.3 4.46 0.37 1.84e-5 Anthropometric traits; TGCT cis rs9467711 0.606 rs9393718 chr6:26407482 G/A cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs908922 0.887 rs4845783 chr1:152492559 G/A cg20991723 chr1:152506922 NA 0.42 5.38 0.43 3.62e-7 Hair morphology; TGCT cis rs7674212 0.541 rs2251322 chr4:104079424 C/T cg16532752 chr4:104119610 CENPE -0.61 -5.67 -0.45 9.45e-8 Type 2 diabetes; TGCT cis rs9611565 0.607 rs132792 chr22:42062822 C/T cg06481639 chr22:41940642 POLR3H 0.59 5.02 0.41 1.77e-6 Vitiligo; TGCT cis rs17376456 0.825 rs34592268 chr5:93232751 G/C cg21475434 chr5:93447410 FAM172A 0.7 4.9 0.4 2.96e-6 Diabetic retinopathy; TGCT cis rs7843479 1.000 rs11775444 chr8:21813018 A/G cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs2153535 0.601 rs9505451 chr6:8469950 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg08859206 chr1:53392774 SCP2 0.34 4.93 0.4 2.63e-6 Monocyte count; TGCT cis rs1372520 0.935 rs1372519 chr4:90757309 A/G cg15133208 chr4:90757351 SNCA -0.47 -5.34 -0.43 4.3e-7 Neuroticism; TGCT cis rs7044106 0.762 rs12003646 chr9:123470621 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.6 0.38 1.05e-5 Hip circumference adjusted for BMI; TGCT cis rs7819412 0.805 rs2409710 chr8:10979821 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.76 -0.39 5.26e-6 Triglycerides; TGCT cis rs10504229 0.636 rs77691549 chr8:58055126 G/T cg21724239 chr8:58056113 NA 0.46 5.01 0.41 1.84e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115506655 chr4:119757667 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs13217239 0.585 rs114919438 chr6:26963792 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.44 -4.88 -0.4 3.18e-6 Schizophrenia; TGCT cis rs595982 0.527 rs17272673 chr19:49362992 C/A cg15549821 chr19:49342101 PLEKHA4 -0.71 -9.62 -0.65 1.07e-16 Red cell distribution width; TGCT cis rs1799949 0.930 rs1554063 chr17:41287145 T/C cg23758822 chr17:41437982 NA 0.68 6.78 0.52 4.4e-10 Menopause (age at onset); TGCT cis rs4689388 0.926 rs12508672 chr4:6287965 G/A cg00701064 chr4:6280414 WFS1 0.38 4.9 0.4 2.87e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs11608355 0.618 rs11066368 chr12:109790342 C/T cg19025524 chr12:109796872 NA -0.27 -4.55 -0.38 1.24e-5 Neuroticism; TGCT cis rs2692947 0.644 rs1168976 chr2:96813480 G/A cg23100626 chr2:96804247 ASTL 0.46 5.42 0.44 3.03e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs11190604 1.000 rs17113137 chr10:102241998 G/C cg23241863 chr10:102295624 HIF1AN 0.64 5.0 0.41 1.92e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs992157 1.000 rs13429408 chr2:219142860 C/A cg00012203 chr2:219082015 ARPC2 0.78 8.39 0.6 9.39e-14 Colorectal cancer; TGCT cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg07061783 chr6:25882402 NA -0.93 -11.08 -0.71 3.03e-20 Urate levels; TGCT cis rs8017423 0.904 rs11621127 chr14:90802050 G/A cg04374321 chr14:90722782 PSMC1 -0.74 -7.15 -0.54 6.48e-11 Mortality in heart failure; TGCT cis rs425277 0.606 rs2257182 chr1:2082566 C/T cg12140144 chr1:2984275 FLJ42875;PRDM16 0.32 4.44 0.37 1.98e-5 Height; TGCT cis rs1534166 0.647 rs13321680 chr3:133507119 G/T cg16414030 chr3:133502952 NA 0.45 5.85 0.47 4.11e-8 Alcohol consumption (transferrin glycosylation); TGCT cis rs3858526 0.920 rs11039548 chr11:5930283 G/A cg05234568 chr11:5960015 NA -0.44 -4.6 -0.38 1.03e-5 DNA methylation (variation); TGCT cis rs6500602 0.627 rs1641866 chr16:4593040 A/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 5.81 0.46 4.98e-8 Schizophrenia; TGCT cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs10992471 0.598 rs2025389 chr9:95157674 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.63 6.12 0.48 1.13e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1865760 0.713 rs2013063 chr6:25994098 C/T cg16482183 chr6:26056742 HIST1H1C 0.54 4.77 0.39 5.15e-6 Height; TGCT cis rs67385638 1.000 rs2855121 chr11:5277291 C/T cg12559170 chr11:5275217 HBG2 0.48 8.71 0.62 1.63e-14 Hemoglobin levels; TGCT cis rs6558530 0.666 rs6558520 chr8:1697573 T/C cg09410841 chr8:1729607 CLN8 0.69 6.2 0.49 7.73e-9 Systolic blood pressure; TGCT cis rs240764 0.853 rs11155496 chr6:100988939 T/C cg21058520 chr6:100914733 NA 0.35 4.63 0.38 9.07e-6 Neuroticism; TGCT cis rs6866344 0.570 rs1071882 chr5:178136040 C/T cg03877680 chr5:178157825 ZNF354A 0.8 7.03 0.53 1.22e-10 Neutrophil percentage of white cells; TGCT cis rs7666738 0.830 rs7673385 chr4:99024922 T/G cg18180107 chr4:99064573 C4orf37 0.55 5.13 0.42 1.1e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.813 rs6999878 chr8:58197243 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.32 -0.43 4.66e-7 Developmental language disorder (linguistic errors); TGCT cis rs4824093 0.610 rs12168949 chr22:50317714 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.15 -4.45 -0.37 1.86e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg13012494 chr21:47604986 C21orf56 -0.38 -4.56 -0.38 1.21e-5 Testicular germ cell tumor; TGCT cis rs910316 1.000 rs175425 chr14:75626131 T/C cg11812906 chr14:75593930 NEK9 -0.73 -7.21 -0.54 4.87e-11 Height; TGCT cis rs9658691 0.790 rs4345878 chr10:90756511 T/C cg03111039 chr10:90751583 FAS;ACTA2 0.63 4.48 0.37 1.71e-5 Mosquito bite size; TGCT cis rs763121 0.853 rs1062687 chr22:39134715 T/C cg06022373 chr22:39101656 GTPBP1 0.73 7.11 0.54 8.14e-11 Menopause (age at onset); TGCT cis rs6840360 0.615 rs10001603 chr4:152647577 T/A cg17479576 chr4:152424074 FAM160A1 -0.53 -5.33 -0.43 4.47e-7 Intelligence (multi-trait analysis); TGCT cis rs72634258 0.503 rs707457 chr1:7831064 C/A cg26816564 chr1:7831052 VAMP3 1.0 7.28 0.55 3.44e-11 Inflammatory bowel disease; TGCT cis rs7809950 0.953 rs2237670 chr7:107131485 A/G cg23024343 chr7:107201750 COG5 -0.34 -5.45 -0.44 2.58e-7 Coronary artery disease; TGCT cis rs7246657 0.943 rs6508732 chr19:38000468 C/T cg18154014 chr19:37997991 ZNF793 0.73 5.43 0.44 2.85e-7 Coronary artery calcification; TGCT cis rs797680 0.856 rs11164880 chr1:93658096 A/C cg17826107 chr1:92977322 EVI5 -0.23 -5.03 -0.41 1.67e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9549260 0.709 rs2721072 chr13:41144919 G/A cg21288729 chr13:41239152 FOXO1 0.98 10.08 0.67 8.21e-18 Red blood cell count; TGCT cis rs7824557 0.628 rs58283816 chr8:11192551 G/C cg21775007 chr8:11205619 TDH 0.7 6.86 0.52 2.93e-10 Retinal vascular caliber; TGCT cis rs3008870 1.000 rs2985821 chr1:67403787 G/A cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.97 0.73 2.07e-22 Lymphocyte percentage of white cells; TGCT cis rs28595532 0.920 rs115860482 chr4:119759546 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs78487399 0.808 rs1388387 chr2:43736969 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.5 0.37 1.57e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6815814 0.950 rs73236633 chr4:38839319 T/C cg02016764 chr4:38805732 TLR1 -0.31 -4.7 -0.39 6.81e-6 Breast cancer; TGCT cis rs2688608 0.901 rs2664280 chr10:75617344 A/T cg04320760 chr10:75533139 FUT11 0.3 4.6 0.38 1.04e-5 Inflammatory bowel disease; TGCT cis rs7119038 0.774 rs73005423 chr11:118681079 A/G cg19308663 chr11:118741387 NA 0.28 5.48 0.44 2.32e-7 Sjögren's syndrome; TGCT cis rs9814567 0.752 rs7623567 chr3:134330976 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs12908161 1.000 rs12905057 chr15:85210765 A/G cg12863693 chr15:85201151 NMB 0.49 5.85 0.47 4.08e-8 Schizophrenia; TGCT cis rs11754661 1.000 rs73011386 chr6:151196854 C/T cg11579907 chr6:151412213 MTHFD1L 0.54 4.9 0.4 2.99e-6 Alzheimer's disease (late onset); TGCT cis rs66573146 0.831 rs68111914 chr4:6986677 C/T cg05069807 chr4:6945702 TBC1D14 0.31 4.83 0.4 3.91e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs769267 0.930 rs2301786 chr19:19413947 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs6430585 0.528 rs78274583 chr2:136734569 C/T cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs10057188 1.000 rs17389148 chr5:77869903 G/T cg06873401 chr5:77792105 LHFPL2 -0.23 -4.58 -0.38 1.14e-5 Pulse pressure; TGCT cis rs79349575 0.783 rs62078370 chr17:47026836 G/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs10927875 0.965 rs3961710 chr1:16313172 C/T cg21385522 chr1:16154831 NA -0.77 -8.44 -0.6 7.05e-14 Dilated cardiomyopathy; TGCT trans rs797680 0.856 rs627779 chr1:93684089 T/C cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs922182 0.547 rs6494458 chr15:64271095 A/C cg02919090 chr15:64263738 DAPK2 -0.28 -4.98 -0.41 2.1e-6 Blood protein levels; TGCT cis rs6570726 0.791 rs6913727 chr6:145899826 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg09177884 chr7:1199841 ZFAND2A -0.65 -6.9 -0.53 2.4e-10 Longevity;Endometriosis; TGCT cis rs2235642 0.691 rs2281235 chr16:1603535 T/C cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.85 -0.46 4.15e-8 Coronary artery disease; TGCT cis rs11785400 0.793 rs2280879 chr8:143722228 T/C cg10596483 chr8:143751796 JRK 0.53 5.23 0.43 7.02e-7 Schizophrenia; TGCT cis rs10782582 0.592 rs7513194 chr1:76382664 A/C cg05598546 chr1:76251766 SNORD45C;RABGGTB -0.55 -4.84 -0.4 3.72e-6 Daytime sleep phenotypes; TGCT trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg26668828 chr6:292823 DUSP22 -0.7 -7.25 -0.55 3.83e-11 Menopause (age at onset); TGCT cis rs8050907 0.744 rs7192051 chr16:4542117 A/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.54 4.74 0.39 5.78e-6 Obesity-related traits; TGCT cis rs6912958 1.000 rs2223880 chr6:88167897 C/T cg12350822 chr6:88032061 C6orf162;GJB7 -0.39 -5.0 -0.41 1.91e-6 Monocyte percentage of white cells; TGCT cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg03188948 chr7:1209495 NA 0.65 5.5 0.44 2.07e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs56309584 0.673 rs11078735 chr17:8116861 C/A cg08322244 chr17:8066669 VAMP2 -0.56 -5.37 -0.43 3.69e-7 Initial pursuit acceleration; TGCT cis rs769267 0.965 rs1469712 chr19:19528821 C/A cg20644253 chr19:19431407 KIAA0892;SF4 0.65 5.4 0.44 3.25e-7 Tonsillectomy; TGCT cis rs1215050 0.765 rs6852699 chr4:98767505 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11096990 0.634 rs6829064 chr4:39291812 G/A cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs9357506 1.000 rs9349355 chr6:46308938 A/G cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs8051431 0.876 rs6499554 chr16:72009439 A/G cg06353428 chr16:71660113 MARVELD3 0.58 4.98 0.41 2.07e-6 LDL cholesterol levels; TGCT cis rs950169 0.922 rs11630507 chr15:85095725 A/G cg17173187 chr15:85201210 NMB 0.51 5.29 0.43 5.25e-7 Schizophrenia; TGCT cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg09177884 chr7:1199841 ZFAND2A -0.61 -6.43 -0.5 2.55e-9 Longevity;Endometriosis; TGCT cis rs644799 0.648 rs1255178 chr11:95471908 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.51 5.05 0.41 1.55e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.51 0.61 4.91e-14 Platelet count; TGCT cis rs478304 0.654 rs10896035 chr11:65461160 G/A cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.8e-13 Acne (severe); TGCT cis rs7726839 0.574 rs12522955 chr5:639231 C/A cg20362242 chr5:692897 TPPP 0.52 4.65 0.39 8.29e-6 Obesity-related traits; TGCT cis rs7296418 0.961 rs1790094 chr12:123586688 T/C cg00376283 chr12:123451042 ABCB9 0.84 7.56 0.56 7.92e-12 Platelet count; TGCT cis rs6460942 0.908 rs77799203 chr7:12264432 C/G cg06484146 chr7:12443880 VWDE -0.55 -4.63 -0.38 9.11e-6 Coronary artery disease; TGCT cis rs1218582 0.596 rs4845676 chr1:154827861 C/G cg06221963 chr1:154839813 KCNN3 -0.55 -7.56 -0.56 7.61e-12 Prostate cancer; TGCT cis rs7829975 0.658 rs2409096 chr8:8692477 T/C cg06636001 chr8:8085503 FLJ10661 0.7 6.2 0.49 7.53e-9 Mood instability; TGCT cis rs7523273 0.606 rs859705 chr1:207959665 A/G cg22525895 chr1:207977042 MIR29B2 0.53 9.01 0.63 3.16e-15 Schizophrenia; TGCT cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs769267 0.895 rs2965189 chr19:19519518 G/T cg03709012 chr19:19516395 GATAD2A 0.74 6.36 0.5 3.48e-9 Tonsillectomy; TGCT cis rs9527 0.615 rs9733635 chr10:104711940 G/A cg04362960 chr10:104952993 NT5C2 0.65 5.5 0.44 2.08e-7 Arsenic metabolism; TGCT cis rs9419702 0.568 rs7093241 chr10:133556596 G/A cg20568497 chr10:133558893 NA 0.46 4.96 0.41 2.27e-6 Survival in rectal cancer; TGCT cis rs6964587 0.610 rs6950682 chr7:91464218 G/T cg17063962 chr7:91808500 NA 0.73 6.7 0.52 6.48e-10 Breast cancer; TGCT cis rs1215050 0.755 rs6843393 chr4:98822619 C/G cg17366294 chr4:99064904 C4orf37 0.56 6.05 0.48 1.57e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2153535 0.580 rs6597318 chr6:8437289 G/A cg23788917 chr6:8435910 SLC35B3 0.61 5.36 0.43 4e-7 Motion sickness; TGCT cis rs68170813 0.559 rs12538769 chr7:106984288 C/T cg02696742 chr7:106810147 HBP1 -0.72 -6.15 -0.48 9.67e-9 Coronary artery disease; TGCT trans rs561341 0.505 rs2344319 chr17:30406189 G/C cg20587970 chr11:113659929 NA -0.99 -8.12 -0.59 4.02e-13 Hip circumference adjusted for BMI; TGCT cis rs12893668 0.703 rs12894729 chr14:104035292 G/A cg26031613 chr14:104095156 KLC1 -0.54 -4.45 -0.37 1.88e-5 Reticulocyte count; TGCT cis rs2050392 0.792 rs9338188 chr10:30721963 G/C cg13289132 chr10:30722225 MAP3K8 -0.39 -4.67 -0.39 7.6e-6 Inflammatory bowel disease; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg08154963 chr17:33426885 RAD51L3 0.64 7.14 0.54 6.91e-11 Gambling; TGCT cis rs17345786 0.906 rs72940399 chr3:101122575 A/T cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 0.900 rs56195309 chr17:28453753 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs832540 1.000 rs252913 chr5:56195846 C/T cg24531977 chr5:56204891 C5orf35 0.5 5.04 0.41 1.58e-6 Coronary artery disease; TGCT cis rs2361718 0.500 rs4889970 chr17:78096086 C/T cg27614120 chr17:77386099 HRNBP3 -0.28 -4.8 -0.4 4.52e-6 Yeast infection; TGCT cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg27286337 chr10:134555280 INPP5A 0.39 4.87 0.4 3.35e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs8017423 0.967 rs61231898 chr14:90691696 G/A cg04374321 chr14:90722782 PSMC1 0.77 8.04 0.59 5.98e-13 Mortality in heart failure; TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs7698623 0.850 rs6532021 chr4:88769661 C/G cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs6429082 0.764 rs2481095 chr1:235695756 T/C cg26050004 chr1:235667680 B3GALNT2 -0.6 -5.25 -0.43 6.43e-7 Adiposity; TGCT cis rs67311347 0.544 rs9814779 chr3:40340431 T/C cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs7552404 0.731 rs61770556 chr1:76421902 T/C cg22875332 chr1:76189707 ACADM 0.63 5.83 0.46 4.42e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9788682 0.748 rs667282 chr15:78863472 T/C cg24631222 chr15:78858424 CHRNA5 0.86 6.45 0.5 2.3e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs12497850 0.931 rs7627404 chr3:48819668 A/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs782590 0.738 rs4312532 chr2:55812061 A/G cg03859395 chr2:55845619 SMEK2 -0.82 -8.88 -0.62 6.4e-15 Metabolic syndrome; TGCT cis rs11785400 0.890 rs13279182 chr8:143720544 A/G cg24634471 chr8:143751801 JRK 0.55 5.7 0.46 8.25e-8 Schizophrenia; TGCT cis rs1775715 0.678 rs2105360 chr10:32210198 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs4665809 1.000 rs12469163 chr2:26283587 T/C cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs7216064 0.651 rs12947658 chr17:65903006 A/G cg12091567 chr17:66097778 LOC651250 0.7 5.85 0.47 4.05e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7809950 0.678 rs2237659 chr7:106847492 G/T cg23024343 chr7:107201750 COG5 0.4 5.53 0.44 1.84e-7 Coronary artery disease; TGCT cis rs1153858 0.723 rs11855527 chr15:45606685 G/A cg26924012 chr15:45694286 SPATA5L1 -0.87 -8.97 -0.63 3.81e-15 Homoarginine levels; TGCT cis rs9611565 0.559 rs132771 chr22:42025350 A/G cg13695892 chr22:41940480 POLR3H 0.86 8.2 0.59 2.63e-13 Vitiligo; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg14893161 chr1:205819251 PM20D1 0.55 7.75 0.57 2.78e-12 Menarche (age at onset); TGCT cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg00484396 chr16:3507460 NAT15 0.46 6.9 0.53 2.42e-10 Tuberculosis; TGCT cis rs7666738 0.791 rs11735105 chr4:98937357 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs111803315 1.000 rs113558975 chr14:59998385 G/A cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs7100689 0.890 rs4934169 chr10:82203663 A/G cg01528321 chr10:82214614 TSPAN14 1.11 11.61 0.72 1.52e-21 Post bronchodilator FEV1; TGCT cis rs597539 0.652 rs654071 chr11:68653432 A/C cg21963583 chr11:68658836 MRPL21 0.36 6.08 0.48 1.35e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3733585 0.648 rs13125029 chr4:9982029 A/G cg11266682 chr4:10021025 SLC2A9 0.58 7.52 0.56 9.77e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs910316 1.000 rs175442 chr14:75603564 T/C cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.71e-6 Height; TGCT cis rs13191362 0.935 rs73008456 chr6:163013697 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7674212 0.541 rs4699050 chr4:104114297 A/G cg16532752 chr4:104119610 CENPE -0.58 -5.37 -0.43 3.66e-7 Type 2 diabetes; TGCT cis rs1799949 0.931 rs34474989 chr17:41445410 A/T cg10047753 chr17:41438598 NA 0.87 8.58 0.61 3.31e-14 Menopause (age at onset); TGCT cis rs832540 0.669 rs832538 chr5:56200016 C/T cg12311346 chr5:56204834 C5orf35 -0.57 -5.84 -0.46 4.33e-8 Coronary artery disease; TGCT cis rs62064224 0.553 rs9915115 chr17:30684858 A/G cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.66e-6 Schizophrenia; TGCT cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.02 0.41 1.76e-6 Platelet count; TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg25767906 chr1:53392781 SCP2 -0.59 -7.49 -0.56 1.12e-11 Monocyte count; TGCT cis rs4699052 0.662 rs6825489 chr4:104250184 T/C cg16532752 chr4:104119610 CENPE -0.5 -4.96 -0.41 2.28e-6 Testicular germ cell tumor; TGCT cis rs13326165 0.760 rs6763882 chr3:52354772 A/G cg27565382 chr3:53032988 SFMBT1 -0.34 -4.68 -0.39 7.5e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6121246 0.908 rs17093657 chr20:30428894 G/A cg18721089 chr20:30220636 NA -0.45 -4.98 -0.41 2.12e-6 Mean corpuscular hemoglobin; TGCT cis rs524281 0.861 rs10896094 chr11:65959206 C/T cg00563793 chr11:65837595 PACS1 0.52 4.5 0.37 1.55e-5 Electroencephalogram traits; TGCT cis rs6088590 0.901 rs6087631 chr20:33403509 T/C cg24642439 chr20:33292090 TP53INP2 0.68 6.06 0.48 1.48e-8 Coronary artery disease; TGCT cis rs2760061 0.583 rs708110 chr1:228190805 T/A cg02753203 chr1:228287806 NA 0.38 7.58 0.56 6.86e-12 Diastolic blood pressure; TGCT trans rs629535 0.862 rs2472141 chr8:70054216 T/C cg21567404 chr3:27674614 NA 0.57 8.67 0.61 2.01e-14 Dupuytren's disease; TGCT cis rs11948739 0.573 rs736046 chr5:130278613 A/G cg08523029 chr5:130500466 HINT1 0.58 4.84 0.4 3.8e-6 Pediatric bone mineral content (hip); TGCT cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.47 -0.37 1.72e-5 Bipolar disorder; TGCT cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg03806693 chr22:41940476 POLR3H 1.34 12.94 0.76 8.97e-25 Vitiligo; TGCT cis rs11031096 0.727 rs12290828 chr11:4144867 C/G cg18678763 chr11:4115507 RRM1 -0.46 -5.7 -0.46 8.24e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg11890956 chr21:40555474 PSMG1 1.09 11.53 0.72 2.41e-21 Cognitive function; TGCT cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg19774624 chr17:42201019 HDAC5 -0.85 -10.09 -0.67 7.79e-18 Total body bone mineral density; TGCT cis rs4891159 0.548 rs654754 chr18:74143695 T/C cg24786174 chr18:74118243 ZNF516 0.65 11.92 0.73 2.63e-22 Longevity; TGCT trans rs17685 0.712 rs56965035 chr7:75795670 G/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2153535 0.580 rs7341201 chr6:8470270 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4711350 1.000 rs10947436 chr6:33739960 A/G cg18005901 chr6:33739558 LEMD2 -0.55 -5.91 -0.47 3.13e-8 Schizophrenia; TGCT cis rs6570726 0.791 rs448939 chr6:145808320 T/C cg13319975 chr6:146136371 FBXO30 -0.56 -4.79 -0.4 4.59e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11690462 0.963 rs13014464 chr2:26581018 C/T cg04726446 chr2:26624865 C2orf39 0.42 4.63 0.38 9.08e-6 Coronary artery disease; TGCT cis rs12478296 0.901 rs59191623 chr2:243028595 G/A cg06360820 chr2:242988706 NA -0.58 -4.74 -0.39 5.66e-6 Obesity-related traits; TGCT cis rs12210905 1.000 rs5030955 chr6:27213867 C/T cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT cis rs10751667 1.000 rs7395691 chr11:985006 T/C cg06064525 chr11:970664 AP2A2 -0.32 -6.18 -0.49 8.28e-9 Alzheimer's disease (late onset); TGCT cis rs3806843 0.576 rs251373 chr5:140252615 C/T cg07102913 chr5:140593443 PCDHB13 0.49 4.71 0.39 6.4e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9677476 0.516 rs6707708 chr2:232020821 T/C cg27665808 chr2:232055229 NA 0.36 4.51 0.38 1.48e-5 Food antigen IgG levels; TGCT cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg03188948 chr7:1209495 NA 0.43 5.56 0.45 1.58e-7 Longevity;Endometriosis; TGCT cis rs7829975 0.714 rs4840362 chr8:8670082 C/G cg06636001 chr8:8085503 FLJ10661 -0.63 -5.54 -0.45 1.72e-7 Mood instability; TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg16697433 chr11:134398473 NA -0.92 -6.77 -0.52 4.48e-10 Follicular lymphoma; TGCT cis rs7917772 0.503 rs746552 chr10:104342501 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 8.21 0.59 2.44e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg27121462 chr16:89883253 FANCA -0.55 -5.23 -0.43 6.92e-7 Vitiligo; TGCT cis rs2228479 0.702 rs17233868 chr16:89803629 C/T cg06558623 chr16:89946397 TCF25 0.45 4.51 0.38 1.47e-5 Skin colour saturation; TGCT cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs3809566 0.636 rs4775604 chr15:63323880 A/C cg08198488 chr15:63333792 TPM1 -0.34 -4.97 -0.41 2.14e-6 Platelet count; TGCT cis rs6121246 0.567 rs6058187 chr20:30190923 T/C cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs2688608 0.905 rs2633300 chr10:75656647 A/C cg02947784 chr10:75434997 AGAP5 0.16 4.56 0.38 1.21e-5 Inflammatory bowel disease; TGCT cis rs76473307 1.000 rs6026563 chr20:57433342 A/G cg06163629 chr20:57414884 GNASAS;GNAS -0.67 -4.58 -0.38 1.11e-5 Chronic lymphocytic leukemia; TGCT cis rs8026198 0.517 rs8024113 chr15:42686838 G/C cg02624051 chr15:42371635 PLA2G4D 0.36 4.47 0.37 1.73e-5 Fibrinogen levels; TGCT trans rs561341 0.882 rs2428337 chr17:30299467 C/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs8028182 0.636 rs7163907 chr15:75845097 T/C cg20655648 chr15:75932815 IMP3 0.62 4.77 0.39 5.07e-6 Sudden cardiac arrest; TGCT cis rs9467711 0.606 rs2235251 chr6:26431982 C/T cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs28595532 0.841 rs114970257 chr4:119756937 G/A cg14228332 chr4:119757509 SEC24D 1.29 6.0 0.47 1.98e-8 Cannabis dependence symptom count; TGCT cis rs6540559 0.673 rs114467813 chr1:210017785 G/A cg21951975 chr1:209979733 IRF6 0.65 4.79 0.39 4.73e-6 Cleft lip with or without cleft palate; TGCT cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg12310025 chr6:25882481 NA -0.48 -4.79 -0.4 4.63e-6 Height; TGCT cis rs4805272 0.539 rs1075733 chr19:29324460 C/T cg12756686 chr19:29218302 NA 0.63 4.53 0.38 1.34e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs797680 0.897 rs2114273 chr1:93854517 T/C cg17826107 chr1:92977322 EVI5 -0.24 -5.6 -0.45 1.29e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1994135 0.692 rs7958788 chr12:33692179 T/C cg06521331 chr12:34319734 NA -0.31 -4.7 -0.39 6.83e-6 Resting heart rate; TGCT cis rs8031584 0.679 rs34017474 chr15:31230611 T/C cg19680485 chr15:31195859 MTMR15 -0.53 -5.13 -0.42 1.09e-6 Huntington's disease progression; TGCT cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg17971929 chr21:40555470 PSMG1 0.95 9.59 0.65 1.22e-16 Cognitive function; TGCT cis rs10504229 0.953 rs6985942 chr8:58173412 T/C cg22535103 chr8:58192502 C8orf71 -0.35 -4.65 -0.39 8.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs3849570 1.000 rs3849570 chr3:81792112 C/A cg07356753 chr3:81810745 GBE1 -0.8 -7.5 -0.56 1.09e-11 Waist circumference;Body mass index; TGCT cis rs1218582 0.772 rs4240874 chr1:154885779 C/T cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs477895 0.838 rs12794145 chr11:64006484 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.84 7.02 0.53 1.3e-10 Mean platelet volume; TGCT cis rs1941023 0.584 rs10750937 chr11:60172087 C/T cg08716584 chr11:60157161 MS4A7 -0.31 -4.69 -0.39 7.18e-6 Congenital heart disease (maternal effect); TGCT cis rs78487399 0.908 rs61754256 chr2:43805739 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2455799 0.613 rs4684259 chr3:15791279 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs2455799 0.613 rs3924773 chr3:15796853 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs9549260 0.620 rs4325427 chr13:41216534 C/T cg21288729 chr13:41239152 FOXO1 0.84 7.92 0.58 1.16e-12 Red blood cell count; TGCT cis rs7726839 0.540 rs72703078 chr5:594987 A/C cg20362242 chr5:692897 TPPP 0.53 4.62 0.38 9.42e-6 Obesity-related traits; TGCT cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg03188948 chr7:1209495 NA 0.46 5.88 0.47 3.5e-8 Longevity;Endometriosis; TGCT cis rs1008375 0.931 rs1860592 chr4:17577028 C/G cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs933688 1.000 rs60513756 chr5:90727692 A/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.03 8.68 0.61 1.89e-14 Smoking behavior; TGCT cis rs4927850 0.521 rs4927679 chr3:195658360 C/T cg12923728 chr3:195709715 SDHAP1 0.26 4.76 0.39 5.2e-6 Pancreatic cancer; TGCT trans rs1005277 0.557 rs176887 chr10:38406094 T/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.73 -7.35 -0.55 2.29e-11 Prostate cancer; TGCT cis rs10751667 0.643 rs7395592 chr11:934094 C/G cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs7635838 0.751 rs2437681 chr3:11594075 A/G cg00170343 chr3:11313890 ATG7 -0.71 -6.46 -0.5 2.15e-9 HDL cholesterol; TGCT cis rs778371 0.723 rs34707169 chr2:233699459 C/T cg08000102 chr2:233561755 GIGYF2 -0.67 -7.64 -0.57 5.21e-12 Schizophrenia; TGCT cis rs3540 0.512 rs7176518 chr15:91079637 C/T cg22089800 chr15:90895588 ZNF774 -0.76 -7.92 -0.58 1.16e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9549367 0.789 rs9549716 chr13:113908478 G/A cg00898013 chr13:113819073 PROZ -0.43 -5.55 -0.45 1.68e-7 Platelet distribution width; TGCT cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg12386194 chr3:101231763 SENP7 -0.59 -5.39 -0.44 3.43e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2197308 0.606 rs12314897 chr12:38392293 C/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT trans rs2970818 0.831 rs2909381 chr12:4606527 T/C cg11728664 chr11:60285636 MS4A13 0.7 6.67 0.51 7.72e-10 Phosphorus levels; TGCT cis rs2239547 0.522 rs2581823 chr3:53022076 C/G cg11645453 chr3:52864694 ITIH4 -0.35 -5.71 -0.46 7.84e-8 Schizophrenia; TGCT cis rs7829975 0.840 rs555617 chr8:8592845 C/G cg15556689 chr8:8085844 FLJ10661 -0.66 -5.73 -0.46 7.27e-8 Mood instability; TGCT cis rs2458413 0.586 rs2669453 chr8:105368930 C/A cg23108931 chr8:105342351 NA 0.31 4.69 0.39 7.04e-6 Paget's disease; TGCT cis rs5769707 0.632 rs135872 chr22:50009300 T/C cg05373962 chr22:49881684 NA -0.29 -4.93 -0.4 2.63e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7772486 0.905 rs9373486 chr6:146446024 C/G cg05347473 chr6:146136440 FBXO30 -0.51 -4.85 -0.4 3.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1215050 0.765 rs6852699 chr4:98767505 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg11644478 chr21:40555479 PSMG1 1.0 10.69 0.69 2.7e-19 Cognitive function; TGCT cis rs36051895 0.589 rs6476950 chr9:5218416 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.17 -0.64 1.29e-15 Pediatric autoimmune diseases; TGCT cis rs1670533 1.000 rs3816474 chr4:1050653 G/A cg20887711 chr4:1340912 KIAA1530 0.69 5.09 0.42 1.31e-6 Recombination rate (females); TGCT cis rs4704846 1.000 rs2902306 chr5:156531561 C/T cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs4654899 0.865 rs6671056 chr1:21488610 G/A cg01072550 chr1:21505969 NA -0.48 -7.14 -0.54 7.03e-11 Superior frontal gyrus grey matter volume; TGCT cis rs6598955 0.670 rs6598942 chr1:26531034 C/T cg04990556 chr1:26633338 UBXN11 -0.88 -11.07 -0.7 3.2e-20 Obesity-related traits; TGCT cis rs11190604 1.000 rs2489045 chr10:102344754 C/T cg23241863 chr10:102295624 HIF1AN 0.66 4.87 0.4 3.37e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9393777 0.582 rs6936561 chr6:26640895 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.59 -5.33 -0.43 4.44e-7 Intelligence (multi-trait analysis); TGCT cis rs9325144 0.678 rs7315271 chr12:39164731 A/G cg26384229 chr12:38710491 ALG10B -0.64 -5.99 -0.47 2.12e-8 Morning vs. evening chronotype; TGCT cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg06481639 chr22:41940642 POLR3H 0.73 6.49 0.5 1.83e-9 Vitiligo; TGCT cis rs9486719 0.857 rs4486027 chr6:96911886 T/C cg18709589 chr6:96969512 KIAA0776 -0.83 -6.73 -0.52 5.74e-10 Migraine;Coronary artery disease; TGCT cis rs7647973 0.961 rs4955443 chr3:49286618 T/G cg07636037 chr3:49044803 WDR6 0.67 5.41 0.44 3.15e-7 Menarche (age at onset); TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg15687855 chr3:44754131 ZNF502 -0.43 -5.23 -0.42 7.08e-7 Depressive symptoms; TGCT cis rs1577917 1.000 rs12196037 chr6:86694631 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.36 -0.43 3.86e-7 Response to antipsychotic treatment; TGCT cis rs2153535 0.580 rs6920779 chr6:8437624 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs1568079 0.516 rs2361382 chr10:125220299 C/G cg02353154 chr10:124578028 NA -0.37 -4.72 -0.39 6.34e-6 Body mass index; TGCT cis rs2456568 0.802 rs10831139 chr11:93640537 G/A cg16099599 chr11:93583650 C11orf90 -0.39 -4.78 -0.39 4.97e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3824867 0.804 rs12419342 chr11:47468545 C/T cg20307385 chr11:47447363 PSMC3 0.7 5.97 0.47 2.32e-8 Mean corpuscular hemoglobin; TGCT cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg10263370 chr3:44754102 ZNF502 -0.45 -5.35 -0.43 4.08e-7 Depressive symptoms; TGCT cis rs3733585 0.699 rs6839490 chr4:9965000 C/G cg11266682 chr4:10021025 SLC2A9 0.44 4.94 0.41 2.45e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9915657 0.870 rs4140902 chr17:70133750 A/G cg06234051 chr17:70120541 SOX9 -0.23 -4.61 -0.38 9.78e-6 Thyroid hormone levels; TGCT cis rs9303401 0.614 rs34941454 chr17:57102742 T/G cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.83 0.46 4.4e-8 Cognitive test performance; TGCT cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9388451 0.805 rs1028481 chr6:126106573 G/T cg10911889 chr6:126070802 HEY2 0.51 5.33 0.43 4.47e-7 Brugada syndrome; TGCT cis rs7552404 0.924 rs1251075 chr1:76190569 C/G cg10523679 chr1:76189770 ACADM 0.85 9.49 0.65 2.17e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11696501 0.588 rs6073831 chr20:44279550 A/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs2456568 0.802 rs11020585 chr11:93638493 A/C cg26875233 chr11:93583750 C11orf90 0.47 6.27 0.49 5.51e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2075371 0.932 rs34664116 chr7:133984878 G/A cg11752832 chr7:134001865 SLC35B4 0.67 5.9 0.47 3.21e-8 Mean platelet volume; TGCT cis rs801193 0.967 rs2420827 chr7:66147101 G/A cg00343986 chr7:65444356 GUSB -0.21 -4.59 -0.38 1.06e-5 Aortic root size; TGCT cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg22508957 chr16:3507546 NAT15 0.51 5.92 0.47 2.89e-8 Tuberculosis; TGCT cis rs6976053 0.875 rs7783543 chr7:100468398 T/C cg03880458 chr7:100306854 NA 0.16 4.44 0.37 1.96e-5 Plasminogen activator inhibitor type 1 levels (PAI-1); TGCT cis rs6460942 0.915 rs62448599 chr7:12453764 C/T cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs858239 0.539 rs6461695 chr7:23197784 C/A cg05602783 chr7:23145260 KLHL7 -0.7 -5.55 -0.45 1.67e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs12580194 0.593 rs59136392 chr12:55748204 C/T cg10672482 chr12:55725839 OR6C3 -0.52 -4.66 -0.39 8.13e-6 Cancer; TGCT cis rs17401966 0.838 rs55676616 chr1:10290126 T/C cg19773385 chr1:10388646 KIF1B -0.22 -4.61 -0.38 9.7e-6 Hepatocellular carcinoma; TGCT cis rs3008870 1.000 rs1118393 chr1:67366668 A/G cg11518657 chr1:67396239 MIER1 0.53 4.72 0.39 6.16e-6 Lymphocyte percentage of white cells; TGCT cis rs1949733 0.675 rs2688219 chr4:8444631 T/C cg11789530 chr4:8429930 ACOX3 0.53 4.99 0.41 2e-6 Response to antineoplastic agents; TGCT cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg11494091 chr17:61959527 GH2 0.39 6.73 0.52 5.49e-10 Height; TGCT cis rs17767294 0.708 rs72848776 chr6:27954826 G/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs11190604 1.000 rs10883506 chr10:102289743 C/G cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3096299 0.503 rs9940093 chr16:89558705 G/A cg06640241 chr16:89574553 SPG7 0.74 8.23 0.59 2.13e-13 Multiple myeloma (IgH translocation); TGCT cis rs13326165 0.715 rs13091545 chr3:52377294 A/G cg07884673 chr3:53033167 SFMBT1 0.39 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7017914 0.905 rs3110250 chr8:71936384 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.69 -0.39 7.05e-6 Prudent dietary pattern; TGCT cis rs10791323 0.569 rs5019134 chr11:133713082 G/C cg03690763 chr11:133734501 NA -0.31 -4.92 -0.4 2.73e-6 Childhood ear infection; TGCT cis rs2594989 0.778 rs6764721 chr3:11470639 A/T cg00170343 chr3:11313890 ATG7 0.74 5.52 0.44 1.9e-7 Circulating chemerin levels; TGCT cis rs4689592 0.503 rs3857180 chr4:7073899 T/G cg26116260 chr4:7069785 GRPEL1 -0.97 -7.65 -0.57 4.97e-12 Monocyte percentage of white cells; TGCT cis rs4663866 1.000 rs71426510 chr2:239178909 T/G cg17283117 chr2:239148619 HES6 0.98 4.52 0.38 1.42e-5 Irritable bowel syndrome; TGCT cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg22963979 chr7:1858916 MAD1L1 -0.45 -7.42 -0.55 1.59e-11 Bipolar disorder and schizophrenia; TGCT cis rs12477438 0.520 rs4347885 chr2:99804007 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs4700695 1.000 rs153319 chr5:65419423 C/T cg21114390 chr5:65439923 SFRS12 -0.62 -4.82 -0.4 4.13e-6 Facial morphology (factor 19); TGCT cis rs1865760 1.000 rs56118523 chr6:25908975 A/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs1127311 0.875 rs9427102 chr1:154586957 A/G cg17218026 chr1:154582156 ADAR 0.3 7.54 0.56 8.85e-12 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs9814567 0.752 rs1534030 chr3:134330083 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3771570 0.901 rs62190415 chr2:242426692 A/G cg21155796 chr2:242212141 HDLBP 0.93 6.69 0.52 6.74e-10 Prostate cancer; TGCT cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg02725872 chr8:58115012 NA -0.38 -4.96 -0.41 2.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs10057188 1.000 rs34797797 chr5:77853085 G/A cg06873401 chr5:77792105 LHFPL2 -0.23 -4.62 -0.38 9.39e-6 Pulse pressure; TGCT cis rs13064411 0.627 rs28536176 chr3:113143625 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.12 -0.42 1.12e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs10832963 1.000 rs11024739 chr11:18645843 A/C cg20219074 chr11:18656078 SPTY2D1 -1.0 -10.15 -0.67 5.35e-18 Breast cancer; TGCT cis rs7095607 0.813 rs1873111 chr10:69922446 T/C cg18986048 chr10:69913749 MYPN 0.48 5.57 0.45 1.54e-7 Lung function (FVC); TGCT cis rs57221529 0.766 rs72703026 chr5:572383 G/A cg09021430 chr5:549028 NA -0.41 -5.52 -0.44 1.9e-7 Lung disease severity in cystic fibrosis; TGCT cis rs9650657 0.655 rs1991651 chr8:10706411 C/G cg27411982 chr8:10470053 RP1L1 0.24 4.98 0.41 2.13e-6 Neuroticism; TGCT cis rs10114408 0.959 rs10992958 chr9:96651789 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1949733 0.959 rs2688242 chr4:8429943 T/G cg11789530 chr4:8429930 ACOX3 0.59 5.33 0.43 4.41e-7 Response to antineoplastic agents; TGCT cis rs13191362 0.872 rs13213421 chr6:163203805 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.12 8.19 0.59 2.72e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6049375 1.000 rs62195318 chr20:24046713 T/C cg14741141 chr20:24973699 C20orf3 0.86 4.92 0.4 2.74e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs9814567 1.000 rs9985356 chr3:134232920 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.9 9.44 0.65 2.92e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6690583 0.623 rs61768852 chr1:85454613 T/C cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs790110 1.000 rs812047 chr3:122382074 C/G cg07366462 chr3:123162899 ADCY5 0.4 4.53 0.38 1.38e-5 Acoustic startle blink response; TGCT cis rs4665809 1.000 rs2384322 chr2:26291146 C/G cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs1005224 0.889 rs9323617 chr14:76158638 A/G cg04684003 chr14:76127793 TTLL5;C14orf1 -0.66 -5.83 -0.46 4.56e-8 Large artery stroke; TGCT cis rs1908814 0.541 rs7824267 chr8:11794279 G/T cg02840367 chr8:11660030 FDFT1 -0.52 -4.47 -0.37 1.73e-5 Neuroticism; TGCT cis rs28493229 0.748 rs10426415 chr19:41183590 A/G cg11601297 chr19:41224147 ITPKC;ADCK4 0.59 5.69 0.46 8.61e-8 Kawasaki disease; TGCT cis rs7666738 0.791 rs1405766 chr4:98965389 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7829975 0.582 rs6982832 chr8:8792217 A/C cg06636001 chr8:8085503 FLJ10661 -0.72 -6.69 -0.52 6.68e-10 Mood instability; TGCT cis rs12620999 0.774 rs13402764 chr2:237951984 C/T cg23555395 chr2:238036564 NA -0.25 -4.77 -0.39 5.07e-6 Systemic lupus erythematosus; TGCT cis rs7224685 0.569 rs8070737 chr17:3981066 G/T cg09580393 chr17:4869866 SPAG7 -0.39 -4.5 -0.37 1.53e-5 Type 2 diabetes; TGCT cis rs7659604 0.539 rs7699776 chr4:122753885 A/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.32 -0.43 4.66e-7 Type 2 diabetes; TGCT cis rs2282802 0.685 rs7715538 chr5:139665181 T/C cg01081189 chr5:139537190 NA 0.28 5.06 0.41 1.46e-6 Intelligence (multi-trait analysis); TGCT cis rs9633740 1.000 rs9633740 chr10:82265271 A/G cg01528321 chr10:82214614 TSPAN14 1.03 8.28 0.6 1.66e-13 Post bronchodilator FEV1; TGCT cis rs2820315 1.000 rs2820310 chr1:201838107 G/A cg12730843 chr1:201915899 LMOD1 -0.27 -4.81 -0.4 4.31e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs7267979 1.000 rs6115159 chr20:25350944 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7635838 0.687 rs9849485 chr3:11395741 G/A cg00170343 chr3:11313890 ATG7 0.65 6.42 0.5 2.57e-9 HDL cholesterol; TGCT cis rs208520 0.874 rs208517 chr6:66947040 G/T cg07460842 chr6:66804631 NA -0.9 -9.15 -0.63 1.45e-15 Exhaled nitric oxide output; TGCT cis rs10744422 1.000 rs4759381 chr12:123348480 G/A cg25930673 chr12:123319894 HIP1R -0.9 -4.99 -0.41 1.96e-6 Schizophrenia; TGCT cis rs9393692 0.905 rs6908328 chr6:26292855 C/A cg05868516 chr6:26286170 HIST1H4H 0.61 5.78 0.46 5.65e-8 Educational attainment; TGCT cis rs61774743 0.754 rs2364544 chr1:41833162 G/A cg01193554 chr1:41846683 NA 0.41 4.91 0.4 2.84e-6 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.527 rs12946522 chr17:56768103 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.54 5.22 0.42 7.25e-7 Cognitive test performance; TGCT cis rs6547741 0.935 rs6749426 chr2:27847606 T/C cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs2204008 0.774 rs11180977 chr12:38263094 G/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs1200821 0.529 rs2475206 chr10:37802532 A/G cg25427524 chr10:38739819 LOC399744 0.31 5.37 0.43 3.76e-7 Hemostatic factors and hematological phenotypes; TGCT cis rs8141529 0.753 rs5752813 chr22:29226570 T/G cg02153584 chr22:29168773 CCDC117 0.68 5.9 0.47 3.26e-8 Lymphocyte counts; TGCT cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg19776793 chr17:79225974 SLC38A10 0.8 6.93 0.53 2.07e-10 Gambling; TGCT cis rs73110464 0.609 rs11170348 chr12:53355588 A/G cg25025879 chr12:53359317 NA -0.52 -5.7 -0.46 8.29e-8 Cancer (pleiotropy); TGCT cis rs10875746 0.903 rs17122666 chr12:48502574 C/T cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs7937612 1.000 rs4938805 chr11:120274211 C/T cg24566217 chr11:120254723 ARHGEF12 0.28 4.56 0.38 1.2e-5 Intraocular pressure; TGCT cis rs644799 1.000 rs632388 chr11:95563775 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4242434 0.889 rs11783129 chr8:22453426 G/A cg03733263 chr8:22462867 KIAA1967 1.1 17.72 0.85 8.65e-36 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs4803468 0.967 rs3826713 chr19:41892269 C/T cg09537434 chr19:41945824 ATP5SL -0.9 -10.06 -0.67 9.09e-18 Height; TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg26338869 chr17:61819248 STRADA -0.54 -5.05 -0.41 1.54e-6 Prudent dietary pattern; TGCT cis rs9393777 0.513 rs9368447 chr6:26646674 A/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.904 rs35285898 chr17:37555872 A/C cg07936489 chr17:37558343 FBXL20 0.65 4.98 0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs13108904 0.870 rs2335855 chr4:1237968 T/C cg13395646 chr4:1353034 KIAA1530 -0.36 -4.65 -0.39 8.47e-6 Obesity-related traits; TGCT cis rs36051895 0.664 rs62541915 chr9:5151275 A/T cg02405213 chr9:5042618 JAK2 -0.7 -8.84 -0.62 8.02e-15 Pediatric autoimmune diseases; TGCT trans rs2469997 1.000 rs2447165 chr8:120371318 G/A cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs2486012 0.850 rs42962 chr1:44298564 A/C cg12908607 chr1:44402522 ARTN -0.69 -5.57 -0.45 1.49e-7 Intelligence (multi-trait analysis); TGCT cis rs2882877 0.648 rs35078179 chr2:190391921 A/C cg10752008 chr2:190445175 SLC40A1 0.62 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs76878669 0.519 rs10791869 chr11:66117113 C/T cg18002602 chr11:66138449 SLC29A2 -0.54 -6.62 -0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs4665809 1.000 rs11678157 chr2:26321526 T/C cg04944784 chr2:26401820 FAM59B -0.67 -5.92 -0.47 2.88e-8 Gut microbiome composition (summer); TGCT cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg17054783 chr10:134559939 INPP5A 0.27 5.24 0.43 6.75e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7226408 0.857 rs2007524 chr18:34450142 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs523522 0.962 rs4767912 chr12:120981202 A/G cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT trans rs10506458 1.000 rs12580997 chr12:63433420 G/A cg22491629 chr6:157744540 C6orf35 -0.96 -8.34 -0.6 1.21e-13 Hemostatic factors and hematological phenotypes; TGCT cis rs7474896 0.583 rs12783272 chr10:38024885 T/G cg25427524 chr10:38739819 LOC399744 -0.37 -5.71 -0.46 7.99e-8 Obesity (extreme); TGCT cis rs11118844 0.843 rs11118848 chr1:221926826 A/G cg04222084 chr1:221915650 DUSP10 0.83 5.6 0.45 1.34e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs734999 0.588 rs4648652 chr1:2535758 A/G cg18854424 chr1:2615690 NA 0.49 5.75 0.46 6.48e-8 Ulcerative colitis; TGCT cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg11890956 chr21:40555474 PSMG1 1.11 12.17 0.74 6.69e-23 Cognitive function; TGCT cis rs45509595 0.841 rs401754 chr6:27782538 T/A cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.24e-6 Breast cancer; TGCT cis rs6121246 0.909 rs3203770 chr20:30382315 A/G cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg20607798 chr8:58055168 NA 0.45 4.62 0.38 9.54e-6 Developmental language disorder (linguistic errors); TGCT trans rs9650657 0.529 rs10108618 chr8:10953092 A/G cg15556689 chr8:8085844 FLJ10661 -0.8 -7.83 -0.58 1.87e-12 Neuroticism; TGCT cis rs367943 0.966 rs348947 chr5:112822795 C/G cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs7584330 0.518 rs74003103 chr2:238446699 G/A cg14458575 chr2:238380390 NA 0.43 4.51 0.38 1.48e-5 Prostate cancer; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg08859206 chr1:53392774 SCP2 -0.42 -6.23 -0.49 6.54e-9 Monocyte count; TGCT cis rs74054849 0.850 rs16851878 chr1:15955610 C/T cg05660106 chr1:15850417 CASP9 0.86 4.48 0.37 1.68e-5 Alcoholic chronic pancreatitis; TGCT cis rs2345546 1 rs2345546 chr16:25427472 C/T cg08360281 chr16:25269390 ZKSCAN2 1.24 9.1 0.63 1.93e-15 Major depression and alcohol dependence; TGCT cis rs7226408 0.842 rs8083264 chr18:34327499 G/A cg06757138 chr18:34340585 FHOD3 0.3 5.14 0.42 1.04e-6 Obesity-related traits; TGCT cis rs9660180 0.780 rs12038111 chr1:1703849 T/C cg17747265 chr1:1875780 NA -0.38 -7.18 -0.54 5.62e-11 Body mass index; TGCT cis rs1461503 0.966 rs1461504 chr11:122845129 T/C cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs12200560 0.505 rs9400167 chr6:97077192 G/T cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs2224391 0.554 rs928170 chr6:5255154 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.14 -0.48 1.01e-8 Height; TGCT cis rs56399783 0.614 rs11765492 chr7:2771642 G/A cg19731401 chr7:2775893 GNA12 0.38 5.36 0.43 3.93e-7 Childhood ear infection; TGCT cis rs2439831 0.681 rs478104 chr15:43594900 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.88 6.42 0.5 2.67e-9 Lung cancer in ever smokers; TGCT cis rs11785400 0.701 rs9721143 chr8:143727511 A/T cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs9400467 0.537 rs12191266 chr6:111528041 T/C cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs853679 0.517 rs3757187 chr6:28107654 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs9902453 0.904 rs7212292 chr17:28409264 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.82 -7.84 -0.58 1.77e-12 Coffee consumption (cups per day); TGCT cis rs270601 0.690 rs162904 chr5:131595784 C/T cg12564285 chr5:131593104 PDLIM4 -0.41 -4.89 -0.4 3e-6 Acylcarnitine levels; TGCT cis rs12908161 1.000 rs17600551 chr15:85319258 A/G cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.04e-8 Schizophrenia; TGCT cis rs11711311 0.747 rs7638449 chr3:113343646 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.68 -5.83 -0.46 4.6e-8 IgG glycosylation; TGCT cis rs10782582 0.592 rs7513194 chr1:76382664 A/C cg10523679 chr1:76189770 ACADM 0.53 4.88 0.4 3.2e-6 Daytime sleep phenotypes; TGCT cis rs826838 1.000 rs1719830 chr12:39096992 T/G cg13010199 chr12:38710504 ALG10B -0.59 -4.88 -0.4 3.25e-6 Heart rate; TGCT cis rs1799949 0.929 rs799905 chr17:41277187 G/C cg10047753 chr17:41438598 NA 0.74 7.04 0.53 1.15e-10 Menopause (age at onset); TGCT cis rs7833790 0.929 rs28464834 chr8:82797356 A/T cg27398817 chr8:82754497 SNX16 0.74 5.19 0.42 8.37e-7 Diastolic blood pressure; TGCT trans rs1496653 0.602 rs36063633 chr3:23384807 G/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs4665809 0.838 rs6546749 chr2:26306288 T/C cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs9303401 0.659 rs62083410 chr17:56964386 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs1218582 0.772 rs11264282 chr1:154867370 G/A cg03351412 chr1:154909251 PMVK 0.52 4.78 0.39 4.93e-6 Prostate cancer; TGCT cis rs617219 0.671 rs2220839 chr5:78603510 T/A cg09550809 chr5:78407562 BHMT -0.37 -5.25 -0.43 6.45e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg03188948 chr7:1209495 NA 0.46 6.02 0.48 1.83e-8 Longevity;Endometriosis; TGCT cis rs4975709 0.589 rs1684967 chr5:1863055 G/C cg15595755 chr5:1867978 NA 0.46 5.38 0.43 3.59e-7 Cardiovascular disease risk factors; TGCT cis rs9388451 0.626 rs3799712 chr6:126075103 A/G cg10911889 chr6:126070802 HEY2 0.5 4.67 0.39 7.61e-6 Brugada syndrome; TGCT cis rs9926296 0.528 rs4785721 chr16:89839997 G/A cg21285383 chr16:89894308 SPIRE2 0.44 6.87 0.53 2.77e-10 Vitiligo; TGCT cis rs1215050 0.740 rs10025482 chr4:99053277 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.35 0.43 4.12e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs66573146 1.000 rs56178503 chr4:6961748 C/T cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs853679 0.546 rs200981 chr6:27833174 A/G cg10876282 chr6:28092338 ZSCAN16 0.75 4.45 0.37 1.88e-5 Depression; TGCT cis rs4788570 0.537 rs56222754 chr16:71491806 G/A cg06353428 chr16:71660113 MARVELD3 -1.33 -7.91 -0.58 1.24e-12 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.682 rs467357 chr16:89717397 A/G cg01097406 chr16:89675127 NA 0.36 6.22 0.49 6.91e-9 Vitiligo; TGCT cis rs68170813 0.652 rs8180747 chr7:107106308 T/C cg02696742 chr7:106810147 HBP1 -0.62 -4.63 -0.38 9.11e-6 Coronary artery disease; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg06873352 chr17:61820015 STRADA 0.54 5.95 0.47 2.51e-8 Prudent dietary pattern; TGCT cis rs7918232 0.941 rs1775350 chr10:27441973 C/T cg14442939 chr10:27389572 ANKRD26 -0.8 -5.32 -0.43 4.7e-7 Breast cancer; TGCT cis rs3806843 1.000 rs7701755 chr5:140182101 G/T cg19875535 chr5:140030758 IK 0.36 6.11 0.48 1.21e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs922182 1.000 rs1460546 chr15:64283108 C/A cg02919090 chr15:64263738 DAPK2 0.31 5.77 0.46 6.05e-8 Blood protein levels; TGCT cis rs6582630 0.537 rs1851124 chr12:38516404 G/A cg13010199 chr12:38710504 ALG10B 0.59 4.77 0.39 5.14e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4924935 0.509 rs28540773 chr17:18761754 T/C cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Pancreatic cancer; TGCT cis rs568617 0.626 rs10896050 chr11:65577516 G/T cg04055107 chr11:65626734 MUS81;CFL1 0.57 4.73 0.39 5.97e-6 Crohn's disease; TGCT cis rs5769765 0.624 rs2285187 chr22:50185432 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.34 4.72 0.39 6.23e-6 Schizophrenia; TGCT cis rs1982963 1.000 rs2749876 chr14:52504397 T/G cg10843707 chr14:52510701 NID2 -0.43 -6.6 -0.51 1.09e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs909002 0.830 rs7542583 chr1:32110813 A/G cg11573219 chr1:32083031 HCRTR1 -0.41 -5.19 -0.42 8.42e-7 Intelligence (multi-trait analysis); TGCT cis rs9549260 0.753 rs10507486 chr13:41186501 A/G cg21288729 chr13:41239152 FOXO1 -0.65 -4.72 -0.39 6.33e-6 Red blood cell count; TGCT trans rs17685 0.712 rs11764119 chr7:75812358 T/G cg19862616 chr7:65841803 NCRNA00174 0.5 8.69 0.62 1.77e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1008375 0.866 rs2109518 chr4:17572162 G/A cg10189774 chr4:17578691 LAP3 0.65 5.65 0.45 1.06e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11031096 0.769 rs12803541 chr11:4208906 G/A cg22027985 chr11:4115532 RRM1 0.43 4.72 0.39 6.23e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs896854 0.530 rs10956934 chr8:95992473 C/A cg23172400 chr8:95962367 TP53INP1 -0.36 -5.6 -0.45 1.3e-7 Type 2 diabetes; TGCT cis rs11190604 1.000 rs2295779 chr10:102296061 A/G cg23241863 chr10:102295624 HIF1AN 0.58 4.55 0.38 1.26e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6964587 1.000 rs57816416 chr7:91736078 A/C cg17063962 chr7:91808500 NA 0.88 9.59 0.65 1.22e-16 Breast cancer; TGCT cis rs9796 0.870 rs3900905 chr15:41260801 G/A cg18705301 chr15:41695430 NDUFAF1 0.43 5.63 0.45 1.13e-7 Menopause (age at onset); TGCT cis rs854765 0.547 rs12150369 chr17:17911014 G/A cg09796270 chr17:17721594 SREBF1 0.25 5.03 0.41 1.65e-6 Total body bone mineral density; TGCT cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg02458000 chr6:26745757 NA -0.51 -4.57 -0.38 1.18e-5 Schizophrenia; TGCT cis rs36051895 0.658 rs11999928 chr9:5006743 T/G cg02405213 chr9:5042618 JAK2 -0.8 -11.07 -0.7 3.18e-20 Pediatric autoimmune diseases; TGCT cis rs11671005 0.735 rs3088284 chr19:58929427 G/A cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT cis rs875971 1.000 rs6958271 chr7:65979331 A/C cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs6969780 1.000 rs6969780 chr7:27159136 G/C cg04317399 chr7:27170313 HOXA4 0.45 4.47 0.37 1.77e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs9300255 0.620 rs1716173 chr12:123660721 A/T cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.68e-8 Neutrophil percentage of white cells; TGCT cis rs79349575 0.679 rs9894239 chr17:46997959 C/T cg26022315 chr17:47021804 SNF8 -0.54 -5.37 -0.43 3.73e-7 Type 2 diabetes; TGCT cis rs9611519 0.894 rs9623320 chr22:41478482 G/A cg13695892 chr22:41940480 POLR3H -0.51 -4.5 -0.37 1.54e-5 Neuroticism; TGCT cis rs2677744 0.719 rs1266492 chr15:91456102 T/C cg23684204 chr15:91497937 RCCD1 0.34 5.04 0.41 1.6e-6 Attention deficit hyperactivity disorder; TGCT cis rs3780378 0.934 rs10815146 chr9:5015901 T/A cg02405213 chr9:5042618 JAK2 -0.54 -7.05 -0.53 1.1e-10 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7833790 0.700 rs7834483 chr8:82704828 A/G cg06027949 chr8:82754900 SNX16 -0.64 -4.85 -0.4 3.56e-6 Diastolic blood pressure; TGCT cis rs5769765 1.000 rs5769765 chr22:50271176 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs4727027 0.704 rs7784122 chr7:148904624 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 -0.52 -4.66 -0.39 8.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7617773 0.784 rs11715799 chr3:48255220 A/G cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs2463822 0.592 rs72919486 chr11:62043501 G/C cg06239285 chr11:62104954 ASRGL1 -0.87 -5.04 -0.41 1.6e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2842992 0.789 rs9365093 chr6:160175819 C/G cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg10117171 chr1:25599238 RHD -0.35 -5.8 -0.46 5.14e-8 Erythrocyte sedimentation rate; TGCT cis rs12497850 0.644 rs11928552 chr3:48739883 T/C cg07636037 chr3:49044803 WDR6 0.92 9.9 0.66 2.24e-17 Parkinson's disease; TGCT cis rs2237234 0.542 rs7755997 chr6:26483048 G/A cg26531700 chr6:26746687 NA 0.53 4.82 0.4 4.1e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs3540 0.533 rs2256110 chr15:90971036 T/C cg22089800 chr15:90895588 ZNF774 0.76 8.15 0.59 3.29e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs651907 0.535 rs11707250 chr3:101509371 A/T cg12386194 chr3:101231763 SENP7 -0.47 -4.7 -0.39 6.87e-6 Colorectal cancer; TGCT cis rs4713118 0.629 rs149899 chr6:28019979 C/T cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs910316 1.000 rs7156328 chr14:75532941 T/C cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs5167 0.781 rs2075619 chr19:45495682 A/G cg09555818 chr19:45449301 APOC2 0.24 5.11 0.42 1.2e-6 Blood protein levels; TGCT cis rs929354 0.742 rs6956046 chr7:156962874 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs59197085 0.515 rs17165198 chr7:128451741 C/T cg00260937 chr7:128520193 KCP -0.46 -5.2 -0.42 8.01e-7 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs72627509 1.000 rs72627509 chr4:57839051 C/G cg26694713 chr4:57773883 REST 0.76 6.61 0.51 1e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2290402 0.536 rs56223707 chr4:881896 C/T cg11315544 chr4:1222440 CTBP1 0.26 4.46 0.37 1.84e-5 Type 2 diabetes; TGCT cis rs9914544 1.000 rs9916245 chr17:18766825 C/G cg26378065 chr17:18585709 ZNF286B 0.52 4.73 0.39 5.94e-6 Educational attainment (years of education); TGCT cis rs6912958 0.712 rs4706294 chr6:88317675 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.57 -0.38 1.16e-5 Monocyte percentage of white cells; TGCT trans rs7618501 1.000 rs7648987 chr3:49868455 A/G cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs17221829 0.733 rs11018688 chr11:89366824 G/T cg02982614 chr11:89391479 FOLH1B -0.28 -4.86 -0.4 3.4e-6 Anxiety in major depressive disorder; TGCT cis rs2014572 0.967 rs8106734 chr19:57763546 C/T cg24459738 chr19:57751996 ZNF805 -0.56 -5.59 -0.45 1.38e-7 Hyperactive-impulsive symptoms; TGCT cis rs78461346 1.000 rs76206767 chr17:80496705 C/T cg15014069 chr17:80540666 FOXK2 0.4 5.04 0.41 1.62e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs7917772 0.599 rs2863717 chr10:104519829 A/G cg05855489 chr10:104503620 C10orf26 0.66 5.25 0.43 6.47e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs79349575 0.811 rs12601072 chr17:46997998 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs4900538 0.855 rs12586378 chr14:102853150 T/C cg18135206 chr14:102964638 TECPR2 -0.2 -4.49 -0.37 1.62e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9300255 0.602 rs949142 chr12:123634043 T/C cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg13695892 chr22:41940480 POLR3H -0.78 -7.52 -0.56 9.73e-12 Vitiligo; TGCT cis rs72634258 0.519 rs744001 chr1:7934557 G/A cg26816564 chr1:7831052 VAMP3 0.65 4.98 0.41 2.11e-6 Inflammatory bowel disease; TGCT cis rs3820068 0.705 rs4646077 chr1:15827136 C/T cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs1218582 0.510 rs2878411 chr1:154823545 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.49 -4.67 -0.39 7.72e-6 Prostate cancer; TGCT cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg05665937 chr4:1216051 CTBP1 -0.24 -4.55 -0.38 1.26e-5 Obesity-related traits; TGCT cis rs854765 0.964 rs854810 chr17:18006421 G/C cg04398451 chr17:18023971 MYO15A 0.3 4.79 0.39 4.75e-6 Total body bone mineral density; TGCT cis rs9911578 1.000 rs9807057 chr17:56889952 A/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs10479542 0.766 rs7733389 chr5:178974997 C/T cg19723775 chr5:179050963 HNRNPH1 0.49 4.96 0.41 2.27e-6 Lung cancer; TGCT cis rs9486715 0.809 rs9486467 chr6:96971803 C/T cg06623918 chr6:96969491 KIAA0776 1.11 15.54 0.81 6.95e-31 Headache; TGCT cis rs12926788 0.542 rs6497759 chr16:24801737 G/A cg06028605 chr16:24865363 SLC5A11 0.41 4.57 0.38 1.17e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9393692 0.676 rs806977 chr6:26189615 A/G cg05868516 chr6:26286170 HIST1H4H 0.53 5.21 0.42 7.76e-7 Educational attainment; TGCT cis rs4654899 0.897 rs59537090 chr1:21498737 C/T cg01072550 chr1:21505969 NA -0.5 -8.08 -0.59 4.94e-13 Superior frontal gyrus grey matter volume; TGCT cis rs1949733 0.523 rs62287455 chr4:8544994 A/T cg13073564 chr4:8508604 NA 0.5 4.89 0.4 3.06e-6 Response to antineoplastic agents; TGCT trans rs4332037 0.539 rs11762636 chr7:2061111 C/A cg25206134 chr2:45395956 NA 0.96 7.31 0.55 2.89e-11 Bipolar disorder; TGCT cis rs9318086 0.687 rs9507182 chr13:24442365 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.77 8.28 0.6 1.66e-13 Myopia (pathological); TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg08859206 chr1:53392774 SCP2 -0.45 -7.11 -0.54 8.09e-11 Monocyte count; TGCT cis rs3733585 0.699 rs6449176 chr4:9967843 G/A cg00071950 chr4:10020882 SLC2A9 -0.57 -6.83 -0.52 3.47e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9911578 1.000 rs4793952 chr17:56608465 C/T cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7698623 0.850 rs4693895 chr4:88797839 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs11031096 0.655 rs35898891 chr11:4211112 G/C cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6570726 0.791 rs374478 chr6:145840022 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs9388451 0.626 rs3799708 chr6:126078530 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.85 -10.17 -0.67 4.96e-18 Brugada syndrome; TGCT cis rs7552404 0.727 rs5745390 chr1:76306591 A/C cg22875332 chr1:76189707 ACADM 0.63 6.74 0.52 5.33e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs908922 0.676 rs1337340 chr1:152508260 T/C cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs56104184 0.775 rs55756106 chr19:49403055 A/G cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs75686122 0.892 rs12676333 chr8:104542372 A/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7178572 0.568 rs12907847 chr15:77493174 C/T cg22256960 chr15:77711686 NA -0.88 -8.99 -0.63 3.53e-15 Type 2 diabetes; TGCT cis rs4851254 0.584 rs35774174 chr2:100655130 T/A cg22139774 chr2:100720529 AFF3 -0.46 -4.97 -0.41 2.16e-6 Intelligence (multi-trait analysis); TGCT cis rs1005277 0.505 rs200935 chr10:38132810 T/A cg25427524 chr10:38739819 LOC399744 -0.37 -7.41 -0.55 1.74e-11 Extrinsic epigenetic age acceleration; TGCT cis rs2235642 0.891 rs2281231 chr16:1601879 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.3 -5.41 -0.44 3.18e-7 Coronary artery disease; TGCT cis rs763014 0.966 rs7185390 chr16:666382 A/G cg00908189 chr16:619842 PIGQ 0.87 10.61 0.69 4.21e-19 Height; TGCT cis rs8141529 0.748 rs132528 chr22:29295898 C/T cg02153584 chr22:29168773 CCDC117 -0.67 -5.22 -0.42 7.25e-7 Lymphocyte counts; TGCT cis rs2180341 0.782 rs6569490 chr6:127729615 C/T cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs1401999 0.659 rs4912518 chr3:183752027 C/T cg01324343 chr3:183735012 ABCC5 -0.76 -9.03 -0.63 2.71e-15 Anterior chamber depth; TGCT cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg06238570 chr21:40685208 BRWD1 0.7 6.45 0.5 2.3e-9 Cognitive function; TGCT cis rs1023500 0.529 rs133375 chr22:42466509 C/G cg15557168 chr22:42548783 NA -0.22 -5.59 -0.45 1.41e-7 Schizophrenia; TGCT cis rs11864453 0.647 rs2550035 chr16:72113416 C/G cg14768367 chr16:72042858 DHODH 0.52 5.26 0.43 6.21e-7 Fibrinogen levels; TGCT cis rs9467711 0.659 rs72845428 chr6:26550144 C/T cg16898833 chr6:26189333 HIST1H4D 1.25 5.86 0.47 3.88e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs155076 0.702 rs482731 chr13:21846075 G/A cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs933688 1.000 rs35712350 chr5:90679519 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.03 9.42 0.65 3.21e-16 Smoking behavior; TGCT cis rs8056742 0.643 rs71386888 chr16:85085937 A/G cg00229868 chr16:85520891 NA 0.36 4.83 0.4 4.03e-6 Amyotrophic lateral sclerosis; TGCT cis rs6866344 0.570 rs1071881 chr5:178135917 C/T cg03877680 chr5:178157825 ZNF354A 0.75 6.45 0.5 2.25e-9 Neutrophil percentage of white cells; TGCT cis rs77633900 0.614 rs2469244 chr15:76884127 G/A cg21673338 chr15:77095150 SCAPER -0.52 -4.83 -0.4 3.88e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs477895 0.653 rs2015226 chr11:63902534 C/T cg23719950 chr11:63933701 MACROD1 -0.71 -5.91 -0.47 3.06e-8 Mean platelet volume; TGCT cis rs10193935 1.000 rs10185742 chr2:42429666 A/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6540559 0.546 rs75308488 chr1:210030639 T/C cg21951975 chr1:209979733 IRF6 0.68 5.11 0.42 1.19e-6 Cleft lip with or without cleft palate; TGCT cis rs2072499 0.966 rs2842865 chr1:156159532 G/A cg06970220 chr1:156163860 SLC25A44 0.72 6.3 0.49 4.62e-9 Testicular germ cell tumor; TGCT cis rs9677476 0.517 rs55970645 chr2:232052494 G/A cg07929768 chr2:232055508 NA 0.31 4.97 0.41 2.14e-6 Food antigen IgG levels; TGCT cis rs2188554 1.000 rs10237738 chr7:117007686 A/G cg08576598 chr7:116962626 WNT2 -0.38 -4.57 -0.38 1.14e-5 Esophageal adenocarcinoma; TGCT cis rs78487399 0.808 rs7567535 chr2:43668261 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3771570 0.901 rs3815262 chr2:242352582 A/T cg21155796 chr2:242212141 HDLBP 0.83 6.19 0.49 8.22e-9 Prostate cancer; TGCT cis rs12908161 1.000 rs60957376 chr15:85280792 T/G cg17173187 chr15:85201210 NMB 0.57 6.38 0.5 3.25e-9 Schizophrenia; TGCT cis rs2242116 0.796 rs4587 chr3:46963502 T/C cg23352942 chr3:46931381 PTH1R -0.32 -4.53 -0.38 1.36e-5 Birth weight; TGCT cis rs2594989 0.831 rs2443703 chr3:11564191 C/T cg26283222 chr3:11613257 VGLL4 0.22 4.45 0.37 1.92e-5 Circulating chemerin levels; TGCT cis rs3848445 1.000 rs3848445 chr17:14294021 C/T cg05091736 chr17:14942129 NA -0.58 -4.96 -0.41 2.29e-6 Protein quantitative trait loci; TGCT cis rs11785400 0.793 rs750530 chr8:143744931 G/A cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT trans rs17685 0.753 rs6951943 chr7:75772452 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs76954792 0.826 rs28524657 chr17:30025992 A/C cg18427091 chr17:30115417 NA -0.36 -4.67 -0.39 7.61e-6 Coronary artery disease; TGCT trans rs28595532 0.748 rs66615663 chr4:119336701 C/T cg26518628 chr1:97050305 NA -0.56 -6.79 -0.52 4.19e-10 Cannabis dependence symptom count; TGCT cis rs2760061 0.583 rs697763 chr1:228192622 G/C cg18477163 chr1:228402036 OBSCN 0.36 7.17 0.54 5.84e-11 Diastolic blood pressure; TGCT cis rs1801251 1.000 rs13004406 chr2:233584557 A/T cg08000102 chr2:233561755 GIGYF2 -0.62 -6.31 -0.49 4.46e-9 Coronary artery disease; TGCT cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs35771425 1.000 rs11577134 chr1:211602624 A/G cg25617285 chr1:211431773 RCOR3 0.5 4.58 0.38 1.13e-5 Educational attainment (years of education); TGCT cis rs350251 0.899 rs350274 chr16:12233259 G/C cg01574788 chr16:12184133 SNX29 0.34 4.48 0.37 1.67e-5 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.816 rs6062397 chr20:61668268 A/G cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs13191362 1.000 rs36113695 chr6:163004733 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs832540 0.898 rs252888 chr5:56227326 T/A cg24531977 chr5:56204891 C5orf35 -0.5 -5.32 -0.43 4.72e-7 Coronary artery disease; TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs34172651 0.517 rs8059004 chr16:24837905 G/A cg06028605 chr16:24865363 SLC5A11 0.41 4.59 0.38 1.05e-5 Intelligence (multi-trait analysis); TGCT cis rs7312774 0.618 rs9651926 chr12:107356820 G/A cg16260113 chr12:107380972 MTERFD3 1.02 5.27 0.43 5.92e-7 Severe influenza A (H1N1) infection; TGCT cis rs9393692 0.905 rs7746807 chr6:26293338 C/A cg05868516 chr6:26286170 HIST1H4H 0.61 5.78 0.46 5.65e-8 Educational attainment; TGCT cis rs7666738 0.515 rs10015315 chr4:98700137 A/G cg18180107 chr4:99064573 C4orf37 0.51 4.55 0.38 1.28e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.541 rs12440854 chr15:43610672 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.92 5.4 0.44 3.26e-7 Lung cancer in ever smokers; TGCT cis rs3935685 0.874 rs4886898 chr15:78004743 T/C cg25212270 chr15:78015279 NA 0.26 5.57 0.45 1.48e-7 Intelligence (multi-trait analysis); TGCT cis rs11031096 0.678 rs10767872 chr11:4184239 T/G cg18678763 chr11:4115507 RRM1 -0.46 -5.95 -0.47 2.5e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs10479542 0.892 rs7736163 chr5:178980316 G/C cg00080972 chr5:178986291 RUFY1 0.46 5.38 0.44 3.5e-7 Lung cancer; TGCT cis rs2806561 0.664 rs55764475 chr1:23318983 C/T cg12483005 chr1:23474871 LUZP1 0.37 4.72 0.39 6.21e-6 Height; TGCT cis rs3008870 0.959 rs2815359 chr1:67494374 T/C cg11518657 chr1:67396239 MIER1 0.52 4.47 0.37 1.73e-5 Lymphocyte percentage of white cells; TGCT cis rs617219 0.698 rs7445125 chr5:78507417 A/G cg23987322 chr5:78407566 BHMT 0.37 4.78 0.39 4.81e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7104764 1.000 rs6598060 chr11:243987 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.08 11.36 0.71 6.01e-21 Menarche (age at onset); TGCT cis rs4780401 0.609 rs4781143 chr16:11809721 T/G cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.07 0.48 1.45e-8 Alzheimer's disease; TGCT cis rs7615952 1.000 rs7615952 chr3:125649403 A/C cg05084668 chr3:125655381 ALG1L 0.83 7.03 0.53 1.23e-10 Blood pressure (smoking interaction); TGCT cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg03264133 chr6:25882463 NA 0.54 4.78 0.39 4.9100000000000004e-06 Intelligence (multi-trait analysis); TGCT cis rs7681440 0.904 rs6816305 chr4:90772902 C/G cg26578617 chr4:90757533 SNCA -0.46 -4.73 -0.39 6.01e-6 Dementia with Lewy bodies; TGCT cis rs4595586 0.545 rs3911798 chr12:39389901 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.47 0.37 1.74e-5 Morning vs. evening chronotype; TGCT cis rs9916302 0.706 rs4795358 chr17:37573065 A/C cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs9430161 0.579 rs9659356 chr1:11034817 A/G cg27631724 chr1:11040367 C1orf127 0.51 5.98 0.47 2.25e-8 Ewing sarcoma; TGCT cis rs6964587 1.000 rs2157747 chr7:91750578 A/G cg22709100 chr7:91322751 NA 0.28 4.52 0.38 1.45e-5 Breast cancer; TGCT cis rs1371867 0.641 rs1788209 chr8:101337056 C/T cg06002616 chr8:101225028 SPAG1 -0.54 -6.29 -0.49 4.88e-9 Atrioventricular conduction; TGCT cis rs7147624 0.517 rs72716457 chr14:66258535 C/G cg03016385 chr14:66212404 NA 0.52 6.0 0.47 2.03e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs651907 0.535 rs11712309 chr3:101519097 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs2721195 0.719 rs4925812 chr8:145808035 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.94 10.08 0.67 8.06e-18 Age at first birth; TGCT cis rs2019137 1.000 rs2019137 chr2:113973632 G/A cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -7.84 -0.58 1.73e-12 Lymphocyte counts; TGCT cis rs916888 0.773 rs199443 chr17:44819565 C/T cg16228356 chr17:43848958 NA -0.26 -4.53 -0.38 1.37e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1580019 0.537 rs7804609 chr7:32558094 A/C cg06627557 chr7:32535165 LSM5;AVL9 1.09 13.35 0.77 9.67e-26 Cognitive ability; TGCT cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs6547741 1.000 rs1919126 chr2:27801418 C/A cg27432699 chr2:27873401 GPN1 0.18 4.64 0.38 8.54e-6 Oral cavity cancer; TGCT cis rs7523050 0.558 rs34880940 chr1:109487731 T/C cg08274380 chr1:109419600 GPSM2 1.06 5.18 0.42 8.64e-7 Fat distribution (HIV); TGCT cis rs6750047 0.609 rs2121259 chr2:38269475 T/C cg07380506 chr2:38303506 CYP1B1 0.61 5.61 0.45 1.23e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg01802117 chr1:53393560 SCP2 -0.45 -5.23 -0.43 7e-7 Monocyte count; TGCT cis rs7772486 0.742 rs4896851 chr6:146278959 T/C cg23711669 chr6:146136114 FBXO30 -0.74 -7.26 -0.55 3.78e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs9868809 0.772 rs2286651 chr3:48694147 G/A cg07636037 chr3:49044803 WDR6 -0.89 -4.69 -0.39 7.23e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7209700 0.708 rs2292699 chr17:45362295 A/G cg21624342 chr17:45890973 OSBPL7 -0.17 -4.8 -0.4 4.51e-6 IgG glycosylation; TGCT cis rs6684514 1.000 rs28372828 chr1:156253031 G/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs35146811 0.735 rs2272345 chr7:99797031 C/G cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs4786125 0.581 rs1473519 chr16:6921533 G/A cg03623568 chr16:6915990 A2BP1 -0.45 -6.68 -0.51 7.28e-10 Heart rate variability traits (SDNN); TGCT cis rs7226408 0.857 rs997661 chr18:34703727 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6912958 0.684 rs2787893 chr6:88387359 C/G cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.91 -0.4 2.79e-6 Monocyte percentage of white cells; TGCT cis rs6845621 0.700 rs6449431 chr4:18894940 C/T cg12196642 chr4:18937545 NA -0.25 -4.57 -0.38 1.15e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs2404602 0.716 rs67888330 chr15:76752483 A/G cg22467129 chr15:76604101 ETFA -0.57 -6.83 -0.52 3.31e-10 Blood metabolite levels; TGCT cis rs2204008 0.811 rs12368410 chr12:38305705 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.22 0.54 4.62e-11 Bladder cancer; TGCT cis rs7552404 1.000 rs437298 chr1:76113770 T/C cg22875332 chr1:76189707 ACADM -0.79 -9.64 -0.65 9.57e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3820068 0.532 rs74057713 chr1:15944620 G/C cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.26e-13 Systolic blood pressure; TGCT cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs7552404 1.000 rs28602663 chr1:76235355 C/T cg10523679 chr1:76189770 ACADM 0.9 9.48 0.65 2.34e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9467711 0.606 rs9379863 chr6:26372427 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs651907 0.535 rs13094753 chr3:101525082 A/G cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.52 -0.51 1.56e-9 Colorectal cancer; TGCT cis rs12510870 0.634 rs11943798 chr4:74407716 C/G cg05868023 chr4:75230803 EREG 0.56 5.05 0.41 1.55e-6 Iris color (b* coordinate); TGCT cis rs10501293 0.675 rs720292 chr11:43036224 T/C cg03447554 chr11:43094025 NA 0.44 6.29 0.49 5.05e-9 Cognitive performance; TGCT cis rs2115630 0.653 rs61394864 chr15:85170174 T/C cg12501888 chr15:85177176 SCAND2 -0.51 -4.7 -0.39 6.89e-6 P wave terminal force; TGCT cis rs1580019 0.587 rs10951338 chr7:32560089 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.14 14.68 0.8 6.88e-29 Cognitive ability; TGCT cis rs950169 1.000 rs35658069 chr15:84780146 C/T cg17173187 chr15:85201210 NMB 0.47 5.23 0.43 7.01e-7 Schizophrenia; TGCT cis rs854765 0.647 rs7211714 chr17:17986955 A/G cg09796270 chr17:17721594 SREBF1 0.23 4.76 0.39 5.35e-6 Total body bone mineral density; TGCT cis rs1018836 0.923 rs7837230 chr8:91574281 C/T cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10089 0.953 rs10223203 chr5:127527646 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.82 -7.4 -0.55 1.81e-11 Ileal carcinoids; TGCT cis rs55883249 0.957 rs62119431 chr2:9750461 G/A cg23886495 chr2:9695866 ADAM17 0.81 5.0 0.41 1.93e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1018836 0.923 rs4735260 chr8:91617157 C/G cg16814680 chr8:91681699 NA 0.84 9.32 0.64 5.66e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.830 rs9884501 chr4:98893721 A/C cg18180107 chr4:99064573 C4orf37 0.53 4.84 0.4 3.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8032315 0.965 rs35346340 chr15:91427872 G/C cg05180856 chr15:91428056 FES 0.25 4.45 0.37 1.89e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs1577917 0.740 rs2842614 chr6:86306069 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.54 -4.87 -0.4 3.28e-6 Response to antipsychotic treatment; TGCT cis rs2721195 0.874 rs2721173 chr8:145744429 C/T cg17328964 chr8:145687451 CYHR1 -0.42 -5.99 -0.47 2.12e-8 Age at first birth; TGCT cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.58 -5.78 -0.46 5.74e-8 Intelligence (multi-trait analysis); TGCT cis rs1670533 1.000 rs11247971 chr4:1053580 A/G cg20887711 chr4:1340912 KIAA1530 0.69 5.54 0.45 1.69e-7 Recombination rate (females); TGCT cis rs9911578 1.000 rs1472288 chr17:56910720 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg02953382 chr22:24373134 LOC391322 -0.75 -7.83 -0.58 1.82e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2439831 0.850 rs28564774 chr15:44125475 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs916888 0.821 rs199505 chr17:44859410 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9653442 0.545 rs13032454 chr2:100756009 T/C cg07810366 chr2:100720526 AFF3 -0.35 -5.0 -0.41 1.88e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7829975 0.593 rs2921061 chr8:8317615 A/T cg15556689 chr8:8085844 FLJ10661 0.66 6.09 0.48 1.31e-8 Mood instability; TGCT cis rs11711311 0.955 rs9823423 chr3:113419741 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.75 -6.72 -0.52 5.86e-10 IgG glycosylation; TGCT cis rs13223928 0.511 rs11773338 chr7:3144508 T/C cg19214707 chr7:3157722 NA -0.46 -6.45 -0.5 2.24e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs8141529 0.748 rs715531 chr22:29282679 A/G cg02153584 chr22:29168773 CCDC117 0.66 5.19 0.42 8.5e-7 Lymphocyte counts; TGCT cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg23172400 chr8:95962367 TP53INP1 -0.38 -6.4 -0.5 2.88e-9 Type 2 diabetes; TGCT cis rs9291683 0.588 rs13113730 chr4:10017628 C/T cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Bone mineral density; TGCT cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs911555 0.755 rs8018400 chr14:103901085 A/G cg23461800 chr14:103021989 NA -0.35 -4.57 -0.38 1.17e-5 Intelligence (multi-trait analysis); TGCT cis rs9534288 0.659 rs2146883 chr13:46660576 C/A cg15192986 chr13:46630673 CPB2 -0.53 -6.41 -0.5 2.75e-9 Blood protein levels; TGCT cis rs7208859 0.623 rs12103508 chr17:29086781 T/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9549260 0.755 rs7988604 chr13:41215802 G/T cg21288729 chr13:41239152 FOXO1 0.97 10.09 0.67 7.57e-18 Red blood cell count; TGCT cis rs260461 0.920 rs79259289 chr19:58752257 T/C cg08291996 chr19:58791159 ZNF8 -0.36 -4.72 -0.39 6.3e-6 Attention deficit hyperactivity disorder; TGCT cis rs7666738 0.606 rs28625338 chr4:99076996 A/G cg05340658 chr4:99064831 C4orf37 0.44 4.77 0.39 5.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7208859 0.623 rs73269945 chr17:29108759 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9926296 0.527 rs1800335 chr16:89846195 A/G cg21285383 chr16:89894308 SPIRE2 0.48 7.73 0.57 3.23e-12 Vitiligo; TGCT cis rs6570726 0.791 rs9373463 chr6:145894762 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg16325326 chr1:53192061 ZYG11B -0.64 -7.45 -0.56 1.38e-11 Monocyte count; TGCT cis rs13424612 0.965 rs2289407 chr2:240954110 A/G cg26363272 chr2:240904871 NDUFA10 0.29 4.99 0.41 2.02e-6 Odorant perception (isobutyraldehyde); TGCT cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg10295955 chr4:187884368 NA -0.94 -14.39 -0.79 3.21e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs2806561 0.734 rs10799788 chr1:23356864 G/A cg12483005 chr1:23474871 LUZP1 0.38 4.76 0.39 5.34e-6 Height; TGCT cis rs763121 0.853 rs2072798 chr22:39148483 G/A cg06022373 chr22:39101656 GTPBP1 0.77 7.17 0.54 6e-11 Menopause (age at onset); TGCT cis rs9534288 0.742 rs7337140 chr13:46641481 C/T cg15192986 chr13:46630673 CPB2 0.49 6.32 0.49 4.28e-9 Blood protein levels; TGCT cis rs514406 0.683 rs10157120 chr1:53210888 A/G cg22166914 chr1:53195759 ZYG11B 0.48 8.96 0.63 4.03e-15 Monocyte count; TGCT cis rs2153535 0.580 rs9328479 chr6:8519646 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs1215050 0.791 rs4699318 chr4:98664370 T/G cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9522267 0.737 rs9522289 chr13:112232110 G/A cg10483660 chr13:112241077 NA -0.28 -4.51 -0.38 1.47e-5 Hepatitis; TGCT cis rs854765 0.647 rs854814 chr17:18003648 G/A cg04398451 chr17:18023971 MYO15A -0.38 -6.53 -0.51 1.52e-9 Total body bone mineral density; TGCT cis rs3125734 0.633 rs4561099 chr10:64041163 T/C cg09941381 chr10:64027924 RTKN2 -0.32 -4.87 -0.4 3.36e-6 Rheumatoid arthritis; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg20007245 chr22:24372913 LOC391322 -0.74 -7.49 -0.56 1.11e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs881375 0.678 rs10118357 chr9:123680068 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 4.85 0.4 3.66e-6 Rheumatoid arthritis; TGCT cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg26531700 chr6:26746687 NA -0.68 -6.72 -0.52 5.75e-10 Schizophrenia; TGCT cis rs4851254 0.579 rs78633727 chr2:100669457 T/C cg22139774 chr2:100720529 AFF3 -0.43 -4.63 -0.38 9.26e-6 Intelligence (multi-trait analysis); TGCT cis rs2702888 0.501 rs2738152 chr8:6752085 A/T cg26795848 chr8:6756730 NA 0.32 6.6 0.51 1.05e-9 Blood pressure; TGCT cis rs2996428 0.667 rs113120570 chr1:3770450 G/C cg17848003 chr1:3704513 LRRC47 0.18 5.15 0.42 9.99e-7 Red cell distribution width; TGCT cis rs6912958 0.559 rs173333 chr6:88047754 T/G cg08069147 chr6:88032118 GJB7;C6orf162 0.72 7.53 0.56 9.05e-12 Monocyte percentage of white cells; TGCT cis rs13191362 1.000 rs34637087 chr6:163004064 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7674212 0.531 rs2866416 chr4:103880711 G/C cg16532752 chr4:104119610 CENPE -0.55 -4.72 -0.39 6.18e-6 Type 2 diabetes; TGCT cis rs10504229 0.861 rs60346509 chr8:58196050 G/T cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs9303401 0.614 rs34683543 chr17:56520036 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.69 6.9 0.53 2.36e-10 Cognitive test performance; TGCT cis rs7666738 0.830 rs10029849 chr4:99059362 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs1974653 0.781 rs9606241 chr22:20075858 A/G cg08822737 chr17:71088851 SLC39A11 -0.71 -6.62 -0.51 9.55e-10 Schizophrenia; TGCT cis rs7824557 0.652 rs12677504 chr8:11133175 G/A cg21775007 chr8:11205619 TDH -0.6 -5.82 -0.46 4.81e-8 Retinal vascular caliber; TGCT cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg16414030 chr3:133502952 NA -0.66 -11.28 -0.71 9.62e-21 Iron status biomarkers; TGCT cis rs2268241 0.938 rs17878783 chr21:34779185 G/A cg14850771 chr21:34775459 IFNGR2 0.61 5.23 0.43 6.88e-7 Obesity-related traits; TGCT cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.84 0.46 4.39e-8 Height; TGCT cis rs3749237 0.595 rs12489092 chr3:49550914 G/C cg02487422 chr3:49467188 NICN1 0.57 5.84 0.46 4.26e-8 Resting heart rate; TGCT cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs3858526 0.584 rs10734559 chr11:5861788 A/C cg13902645 chr11:5959945 NA -0.37 -4.51 -0.38 1.47e-5 DNA methylation (variation); TGCT cis rs1008375 0.931 rs3796814 chr4:17602033 G/C cg16339924 chr4:17578868 LAP3 0.64 5.22 0.42 7.4e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9443645 0.901 rs6940637 chr6:79705845 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs896854 0.846 rs2340584 chr8:95916811 A/G cg23172400 chr8:95962367 TP53INP1 -0.34 -5.49 -0.44 2.2e-7 Type 2 diabetes; TGCT cis rs514406 0.825 rs3863643 chr1:53224577 C/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.41 2.55e-6 Monocyte count; TGCT cis rs265548 0.538 rs36688 chr19:17911212 A/C cg03316864 chr19:17906309 B3GNT3 0.47 5.67 0.45 9.52e-8 Tumor biomarkers; TGCT cis rs7246657 0.712 rs4803263 chr19:38066782 G/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs597539 0.615 rs629426 chr11:68671104 A/G cg06112835 chr11:68658793 MRPL21 0.47 8.28 0.6 1.65e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17221829 0.965 rs11018753 chr11:89459064 T/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.75 -0.39 5.63e-6 Anxiety in major depressive disorder; TGCT cis rs9341808 0.754 rs9352817 chr6:81025879 T/G cg08355045 chr6:80787529 NA 0.28 4.74 0.39 5.73e-6 Sitting height ratio; TGCT cis rs813218 0.565 rs4244712 chr3:99679461 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 5.63 0.45 1.12e-7 Orofacial clefts; TGCT cis rs78456975 0.527 rs10206020 chr2:1557927 A/G cg01028140 chr2:1542097 TPO -0.33 -5.12 -0.42 1.14e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs910187 1.000 rs910187 chr20:45841052 A/G cg27589058 chr20:45804311 EYA2 0.31 5.76 0.46 6.24e-8 Migraine; TGCT cis rs11098499 0.730 rs12505735 chr4:120532956 G/T cg09307838 chr4:120376055 NA 0.68 6.33 0.49 4.11e-9 Corneal astigmatism; TGCT cis rs7192750 0.586 rs11648353 chr16:71986764 G/A cg06353428 chr16:71660113 MARVELD3 0.74 6.6 0.51 1.09e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7147624 0.573 rs10148699 chr14:66199662 G/A cg03016385 chr14:66212404 NA -0.5 -7.04 -0.53 1.13e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg04267008 chr7:1944627 MAD1L1 -0.4 -5.27 -0.43 5.73e-7 Bipolar disorder and schizophrenia; TGCT cis rs13191362 0.810 rs35509380 chr6:163053028 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.89 6.39 0.5 3.1e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12762955 0.519 rs10795306 chr10:1019138 A/T cg26597838 chr10:835615 NA -0.46 -6.3 -0.49 4.79e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs6840360 0.571 rs17360371 chr4:152565374 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs938554 0.779 rs7442295 chr4:9966380 A/G cg11197905 chr4:10459435 ZNF518B -0.29 -4.54 -0.38 1.32e-5 Blood metabolite levels; TGCT cis rs6951245 1.000 rs79443843 chr7:1075245 G/A cg03188948 chr7:1209495 NA 0.59 4.8 0.4 4.57e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs597539 0.731 rs664229 chr11:68624483 C/G cg06112835 chr11:68658793 MRPL21 0.5 8.25 0.6 1.92e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs62283056 0.636 rs62283057 chr4:6276805 C/T cg25554036 chr4:6271136 WFS1 -0.51 -4.75 -0.39 5.48e-6 Cisplatin-induced ototoxicity; TGCT cis rs894734 0.535 rs2366142 chr12:54323148 T/C cg17708016 chr12:54321992 NA 0.69 5.75 0.46 6.56e-8 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); TGCT cis rs7769051 0.711 rs7770081 chr6:133089569 G/T cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs7819412 0.775 rs2898257 chr8:10935368 A/C cg21775007 chr8:11205619 TDH -0.5 -4.61 -0.38 9.74e-6 Triglycerides; TGCT cis rs6088580 0.601 rs6059827 chr20:33016358 C/T cg08999081 chr20:33150536 PIGU 0.29 5.74 0.46 6.86e-8 Glomerular filtration rate (creatinine); TGCT cis rs172166 0.516 rs2622322 chr6:28117443 C/G cg13525197 chr6:28411240 ZSCAN23 -0.46 -4.5 -0.37 1.53e-5 Cardiac Troponin-T levels; TGCT cis rs6882046 0.513 rs679232 chr5:88054763 A/C cg24804195 chr5:87968844 LOC645323 0.57 5.58 0.45 1.42e-7 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs112591243 0.685 rs2839323 chr21:47978421 G/A cg10657630 chr21:48055338 PRMT2 1.0 5.29 0.43 5.4e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs8050907 0.744 rs7195782 chr16:4539861 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.58 4.65 0.39 8.46e-6 Obesity-related traits; TGCT cis rs42648 0.837 rs4728879 chr7:89924237 T/G cg25739043 chr7:89950458 NA -0.75 -7.35 -0.55 2.31e-11 Homocysteine levels; TGCT cis rs10791097 0.694 rs4370948 chr11:130755700 A/C cg14779329 chr11:130786720 SNX19 0.29 4.97 0.41 2.21e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7089973 0.604 rs7915943 chr10:116618077 G/A cg03647239 chr10:116582469 FAM160B1 0.56 5.41 0.44 3.06e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs6089584 0.566 rs6061964 chr20:60607536 G/A cg06108461 chr20:60628389 TAF4 -0.44 -5.58 -0.45 1.44e-7 Body mass index; TGCT cis rs7267979 1.000 rs6050542 chr20:25318879 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs114540395 0.858 rs79692612 chr10:103322878 G/A cg10198749 chr1:39920707 MACF1 0.55 7.05 0.53 1.11e-10 Schizophrenia; TGCT cis rs2721195 0.816 rs4925826 chr8:145706276 G/A cg11211951 chr8:145729740 GPT 0.27 6.36 0.5 3.48e-9 Age at first birth; TGCT cis rs892961 0.932 rs7216116 chr17:75405078 C/T cg05865280 chr17:75406074 SEPT9 0.29 6.76 0.52 4.91e-10 Airflow obstruction; TGCT cis rs9914544 0.689 rs1634423 chr17:18844736 C/T cg26378065 chr17:18585709 ZNF286B 0.55 5.21 0.42 7.59e-7 Educational attainment (years of education); TGCT cis rs7666738 0.830 rs28444709 chr4:99028496 A/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3820928 1.000 rs7579961 chr2:227776976 T/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs9399137 0.529 rs7739722 chr6:135282225 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs1868673 0.679 rs6414375 chr3:150139360 A/G cg24290546 chr3:150134309 TSC22D2 -0.25 -4.67 -0.39 7.66e-6 Waist circumference; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg12419862 chr22:24373484 LOC391322 0.87 7.7 0.57 3.63e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7547997 0.615 rs34591069 chr1:158316990 G/C cg07950803 chr1:158223934 CD1A 0.32 5.08 0.42 1.35e-6 QRS duration; TGCT cis rs11792861 0.591 rs7027874 chr9:111717112 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.67 7.73 0.57 3.13e-12 Menarche (age at onset); TGCT cis rs9467603 0.925 rs4712969 chr6:25764192 A/G cg16898833 chr6:26189333 HIST1H4D -0.99 -4.75 -0.39 5.62e-6 Intelligence (multi-trait analysis); TGCT cis rs259282 0.605 rs73028624 chr19:33111758 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.62 5.56 0.45 1.59e-7 Schizophrenia; TGCT cis rs17376456 0.877 rs10035340 chr5:93490465 C/T cg25358565 chr5:93447407 FAM172A 0.97 8.32 0.6 1.34e-13 Diabetic retinopathy; TGCT cis rs12477438 0.784 rs13407840 chr2:99569928 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs2025751 0.574 rs1326610 chr6:51590078 A/G cg20180370 chr6:50691003 TFAP2D 0.47 4.54 0.38 1.31e-5 Intraocular pressure; TGCT cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.53 5.07 0.41 1.42e-6 Electroencephalogram traits; TGCT trans rs9467711 1.000 rs6908156 chr6:26322861 C/T cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs2172802 0.924 rs11131331 chr4:62446700 C/T cg04118610 chr4:62707027 LPHN3 -0.39 -4.57 -0.38 1.15e-5 Partial epilepsies; TGCT cis rs11190604 0.806 rs76835764 chr10:102193612 C/T cg16342193 chr10:102329863 NA -0.41 -5.2 -0.42 8.01e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs13191362 0.935 rs7769048 chr6:163010040 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6554196 0.686 rs13106834 chr4:55501728 C/T cg02821500 chr4:54931072 CHIC2 -0.47 -4.54 -0.38 1.31e-5 Monocyte count; TGCT cis rs7666738 0.830 rs10022331 chr4:98960392 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs376008 0.526 rs447009 chr19:18185192 C/A cg15085805 chr19:18433592 LSM4 0.54 4.53 0.38 1.37e-5 Blood protein levels; TGCT cis rs7666738 0.830 rs13134216 chr4:98919765 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.51 0.56 1e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs288326 0.561 rs76304059 chr2:183779555 C/G cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs2204008 0.774 rs10400552 chr12:38393577 C/G cg13010199 chr12:38710504 ALG10B 0.59 4.68 0.39 7.35e-6 Bladder cancer; TGCT cis rs10504229 1.000 rs111915672 chr8:58191665 T/C cg08219700 chr8:58056026 NA 0.3 4.48 0.37 1.66e-5 Developmental language disorder (linguistic errors); TGCT cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg11301795 chr4:187892539 NA -0.34 -5.22 -0.42 7.29e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.729 rs12165508 chr22:41819960 T/C cg17554472 chr22:41940697 POLR3H 0.46 5.0 0.41 1.89e-6 Vitiligo; TGCT cis rs3020736 0.500 rs4147641 chr22:42482502 C/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10484885 0.824 rs28372875 chr6:90529343 C/T cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs36093844 0.898 rs11234457 chr11:85591041 C/T cg25872744 chr11:85566296 CCDC83 -0.52 -4.73 -0.39 6.09e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs12477438 0.501 rs2632260 chr2:99771590 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.47 0.86 2.08e-37 Chronic sinus infection; TGCT cis rs12989701 0.825 rs873270 chr2:127859418 T/C cg08168897 chr2:127865431 BIN1 0.52 5.56 0.45 1.55e-7 Alzheimer's disease (late onset); TGCT cis rs79349575 0.783 rs2112617 chr17:46977125 G/A cg27201301 chr17:47039149 GIP 0.26 4.68 0.39 7.38e-6 Type 2 diabetes; TGCT cis rs2730245 0.550 rs2788478 chr7:158672619 A/G cg24397884 chr7:158709396 WDR60 0.37 4.93 0.4 2.63e-6 Height; TGCT cis rs546131 0.642 rs537873 chr11:34835121 A/G cg06937548 chr11:34938143 PDHX;APIP 0.58 4.94 0.41 2.45e-6 Lung disease severity in cystic fibrosis; TGCT cis rs9611519 0.894 rs4821990 chr22:41438710 A/C cg03806693 chr22:41940476 POLR3H -0.67 -6.09 -0.48 1.3e-8 Neuroticism; TGCT cis rs9868809 0.649 rs3733086 chr3:48699519 C/T cg07636037 chr3:49044803 WDR6 -0.89 -4.69 -0.39 7.23e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs250677 0.522 rs11954893 chr5:148392362 A/G cg18129178 chr5:148520854 ABLIM3 -0.35 -4.58 -0.38 1.12e-5 Breast cancer; TGCT cis rs6141600 0.627 rs2746102 chr20:34689247 G/A cg09179691 chr20:35094251 DLGAP4 -0.19 -4.58 -0.38 1.1e-5 Height;Hip circumference; TGCT cis rs8077889 0.917 rs9901676 chr17:41911818 T/C cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs7611238 0.560 rs6801315 chr3:195072820 A/G cg27323046 chr3:195102265 ACAP2 0.37 4.98 0.41 2.1e-6 Body mass index; TGCT cis rs8014204 0.762 rs7144654 chr14:75298637 A/G cg06637938 chr14:75390232 RPS6KL1 0.57 5.07 0.41 1.4e-6 Caffeine consumption; TGCT cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs13326165 0.760 rs390802 chr3:52431671 G/A cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7513165 0.660 rs12040249 chr1:204158228 C/T cg04791601 chr1:204159016 NA 0.26 5.38 0.43 3.61e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs7681440 0.835 rs6831847 chr4:90785341 A/G cg26578617 chr4:90757533 SNCA 0.45 4.59 0.38 1.05e-5 Dementia with Lewy bodies; TGCT trans rs9951602 0.512 rs9949512 chr18:76641845 T/C cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs111803315 1.000 rs78177356 chr14:60008967 A/G cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs11874712 1.000 rs7244921 chr18:43667528 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs6964587 0.773 rs62467797 chr7:91889722 G/A cg17063962 chr7:91808500 NA 0.83 7.96 0.58 9.29e-13 Breast cancer; TGCT cis rs992157 0.560 rs6436048 chr2:219109033 C/T cg00012203 chr2:219082015 ARPC2 0.78 8.94 0.63 4.67e-15 Colorectal cancer; TGCT cis rs9522267 0.707 rs9522282 chr13:112222410 T/C cg10483660 chr13:112241077 NA -0.27 -4.46 -0.37 1.78e-5 Hepatitis; TGCT cis rs9303401 0.659 rs34426768 chr17:56683385 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7523273 0.565 rs1359147 chr1:207886150 C/T cg22525895 chr1:207977042 MIR29B2 0.35 5.75 0.46 6.69e-8 Schizophrenia; TGCT cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.89 7.32 0.55 2.74e-11 Platelet count; TGCT cis rs6951245 0.554 rs11761322 chr7:1151657 A/G cg23708337 chr7:1209742 NA 0.44 4.99 0.41 2e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6089829 0.962 rs1116450 chr20:61658210 T/C cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.45 0.56 1.42e-11 Prudent dietary pattern; TGCT cis rs7264396 0.790 rs3787164 chr20:34228866 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.68 -0.39 7.38e-6 Total cholesterol levels; TGCT cis rs12142240 0.698 rs72677593 chr1:46824363 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs2188554 0.667 rs213949 chr7:117197031 T/A cg08576598 chr7:116962626 WNT2 -0.36 -4.56 -0.38 1.23e-5 Esophageal adenocarcinoma; TGCT cis rs6969780 1.000 rs6461985 chr7:27150634 T/C cg04321618 chr7:27170880 HOXA4 0.55 4.9 0.4 2.97e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg19774624 chr17:42201019 HDAC5 -0.87 -10.64 -0.69 3.48e-19 Total body bone mineral density; TGCT cis rs6500602 1.000 rs7204827 chr16:4467533 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.11 0.42 1.17e-6 Schizophrenia; TGCT cis rs1865760 0.622 rs9968910 chr6:26072095 A/C cg16482183 chr6:26056742 HIST1H1C 0.68 5.61 0.45 1.28e-7 Height; TGCT cis rs1218582 0.772 rs2102423 chr1:154916068 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.68 -6.98 -0.53 1.62e-10 Prostate cancer; TGCT cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs10089 1.000 rs1559263 chr5:127512873 A/C cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.25e-5 Ileal carcinoids; TGCT cis rs2456568 0.548 rs10466334 chr11:93663512 A/G cg17595323 chr11:93583763 C11orf90 -0.42 -5.26 -0.43 6.2e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4273100 0.646 rs2296981 chr17:19213335 C/G cg01534423 chr17:18965556 NA -0.79 -6.76 -0.52 4.91e-10 Schizophrenia; TGCT cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg12310025 chr6:25882481 NA -0.64 -5.73 -0.46 7.07e-8 Intelligence (multi-trait analysis); TGCT cis rs12216125 0.554 rs6942196 chr6:26072804 A/G cg17042849 chr6:26104293 HIST1H4C -0.63 -5.5 -0.44 2.1e-7 Iron status biomarkers; TGCT cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg20637647 chr7:64974828 NA 0.96 5.18 0.42 8.81e-7 Diabetic kidney disease; TGCT cis rs67478160 0.608 rs11628787 chr14:104323984 G/A cg26031613 chr14:104095156 KLC1 0.67 6.73 0.52 5.51e-10 Schizophrenia; TGCT cis rs6840360 0.550 rs6535806 chr4:152483906 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs877282 0.853 rs11596346 chr10:756673 A/T cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs3733631 1.000 rs17034046 chr4:104659604 C/T cg24090629 chr4:104641072 TACR3 -0.73 -6.03 -0.48 1.76e-8 Menarche (age at onset); TGCT cis rs5750830 0.594 rs5757647 chr22:39775047 C/A cg05872129 chr22:39784769 NA -0.84 -8.83 -0.62 8.39e-15 Intelligence (multi-trait analysis); TGCT cis rs12210905 0.920 rs9366690 chr6:27291079 T/C cg08851530 chr6:28072375 NA 1.29 5.45 0.44 2.65e-7 Hip circumference adjusted for BMI; TGCT cis rs10262995 1.000 rs28619003 chr7:33548225 C/T cg06206957 chr7:33080615 NT5C3 0.31 4.53 0.38 1.37e-5 Acute kidney injury in coronary artery bypass surgery (creatinine rise); TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg02073558 chr3:44770973 ZNF501 -0.61 -5.94 -0.47 2.69e-8 Depressive symptoms; TGCT cis rs7647973 0.922 rs6809851 chr3:49309787 C/A cg05785598 chr3:49045655 WDR6 0.38 4.5 0.37 1.57e-5 Menarche (age at onset); TGCT cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg08280861 chr8:58055591 NA 0.49 5.38 0.43 3.64e-7 Developmental language disorder (linguistic errors); TGCT cis rs2576037 0.583 rs2164104 chr18:44567743 G/C cg23302884 chr18:44338147 ST8SIA5 0.41 4.81 0.4 4.25e-6 Personality dimensions; TGCT cis rs6964587 1.000 rs416 chr7:91580571 A/G cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs7824557 0.628 rs3174048 chr8:11184937 G/A cg21775007 chr8:11205619 TDH 0.66 6.47 0.5 2.08e-9 Retinal vascular caliber; TGCT cis rs36051895 0.658 rs7875265 chr9:5033882 C/A cg02405213 chr9:5042618 JAK2 -0.83 -11.82 -0.73 4.65e-22 Pediatric autoimmune diseases; TGCT cis rs1499614 1.000 rs1267818 chr7:66107024 C/T cg18252515 chr7:66147081 NA -1.23 -7.53 -0.56 9.12e-12 Gout; TGCT cis rs1046896 0.553 rs1044661 chr17:80901020 G/A cg03160526 chr17:80928410 B3GNTL1 0.33 4.53 0.38 1.38e-5 Glycated hemoglobin levels; TGCT cis rs314370 0.951 rs12705095 chr7:100484381 T/G cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg14262678 chr6:151773367 RMND1;C6orf211 0.51 4.72 0.39 6.14e-6 Menarche (age at onset); TGCT cis rs425277 0.585 rs3107157 chr1:2061969 A/G cg24578937 chr1:2090814 PRKCZ -0.24 -5.9 -0.47 3.24e-8 Height; TGCT cis rs11208691 0.513 rs1938484 chr1:66081282 C/A cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 Lymphocyte percentage of white cells; TGCT cis rs9527 0.590 rs2066322 chr10:104909339 T/G cg04362960 chr10:104952993 NT5C2 0.65 5.59 0.45 1.36e-7 Arsenic metabolism; TGCT cis rs9341808 0.718 rs2322630 chr6:80841033 A/G cg08355045 chr6:80787529 NA 0.33 6.02 0.48 1.82e-8 Sitting height ratio; TGCT cis rs9914544 0.545 rs57035178 chr17:18797767 C/T cg26378065 chr17:18585709 ZNF286B 0.51 4.59 0.38 1.09e-5 Educational attainment (years of education); TGCT cis rs763014 0.932 rs2269559 chr16:682297 T/C cg00908189 chr16:619842 PIGQ 0.87 10.68 0.69 2.85e-19 Height; TGCT trans rs4650994 1.000 rs4511075 chr1:178518636 G/A cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.37e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9733 0.596 rs12072339 chr1:150686099 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs3617 0.625 rs7652667 chr3:52866535 C/A cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7614311 0.681 rs73117036 chr3:63892725 G/C cg22134162 chr3:63841271 THOC7 -0.4 -5.16 -0.42 9.41e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs4919694 1.000 rs12253284 chr10:104665145 G/C cg04362960 chr10:104952993 NT5C2 1.02 6.9 0.53 2.41e-10 Arsenic metabolism; TGCT cis rs1801251 0.964 rs7589201 chr2:233724536 A/G cg25237894 chr2:233734115 C2orf82 -0.31 -5.45 -0.44 2.57e-7 Coronary artery disease; TGCT cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 4.69 0.39 7.11e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3772130 0.962 rs6789736 chr3:121543084 T/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs611744 0.967 rs475865 chr8:109235858 G/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7208859 0.623 rs11652631 chr17:29060766 A/G cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs4820539 1.000 rs916585 chr22:23469438 G/A cg21100191 chr22:23484243 RTDR1 0.89 10.61 0.69 4.23e-19 Bone mineral density; TGCT cis rs1348850 0.567 rs7605493 chr2:178534983 C/G cg22681709 chr2:178499509 PDE11A -0.46 -5.95 -0.47 2.58e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2153535 0.580 rs7743995 chr6:8496212 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs61990749 0.544 rs176962 chr14:78185510 T/C cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs732765 0.689 rs12411 chr14:75409043 T/A cg06637938 chr14:75390232 RPS6KL1 0.65 5.36 0.43 3.85e-7 Non-small cell lung cancer; TGCT cis rs853679 0.550 rs9295762 chr6:28155418 C/T cg12963246 chr6:28129442 ZNF389 -0.47 -4.82 -0.4 4.2e-6 Depression; TGCT cis rs7216064 1.000 rs56148300 chr17:65892752 T/C cg12091567 chr17:66097778 LOC651250 -0.84 -6.17 -0.48 8.94e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs10788264 0.569 rs10749454 chr10:124029654 C/T cg09507567 chr10:124027408 NA 0.43 6.72 0.52 6.02e-10 Total body bone mineral density; TGCT cis rs208520 0.661 rs207079 chr6:66770462 C/T cg07460842 chr6:66804631 NA -0.92 -10.19 -0.68 4.36e-18 Exhaled nitric oxide output; TGCT cis rs782590 0.902 rs2586947 chr2:55854009 C/G cg03859395 chr2:55845619 SMEK2 0.91 11.16 0.71 1.92e-20 Metabolic syndrome; TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg19626725 chr5:178986131 RUFY1 -0.54 -7.39 -0.55 1.94e-11 Lung cancer; TGCT cis rs6484504 0.576 rs208093 chr11:31184400 C/T cg14844989 chr11:31128820 NA 0.27 5.0 0.41 1.93e-6 Red blood cell count; TGCT cis rs7552404 0.696 rs10782602 chr1:76464261 T/C cg10523679 chr1:76189770 ACADM 0.84 7.2 0.54 4.99e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7513165 0.736 rs4889 chr1:204159787 G/C cg04791601 chr1:204159016 NA 0.26 5.21 0.42 7.68e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs9677476 0.516 rs10206322 chr2:232050072 T/C cg07929768 chr2:232055508 NA 0.32 5.05 0.41 1.53e-6 Food antigen IgG levels; TGCT cis rs62229266 0.771 rs2835232 chr21:37393427 G/A cg08632701 chr21:37451849 NA -0.14 -4.44 -0.37 1.99e-5 Mitral valve prolapse; TGCT cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs2749592 0.611 rs176888 chr10:38406161 C/A cg25427524 chr10:38739819 LOC399744 -0.41 -7.01 -0.53 1.36e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs7666738 0.791 rs10022061 chr4:98926821 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs921968 0.541 rs7583449 chr2:219403022 A/C cg02176678 chr2:219576539 TTLL4 -0.49 -6.94 -0.53 1.95e-10 Mean corpuscular hemoglobin concentration; TGCT trans rs6089829 0.962 rs4997812 chr20:61663153 T/G cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs263156 0.967 rs263107 chr6:142878480 G/A cg18419694 chr6:143832440 FUCA2 -0.38 -4.53 -0.38 1.36e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs66573146 0.803 rs59742225 chr4:6969942 C/T cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2050392 0.965 rs2265370 chr10:30690581 C/T cg18806716 chr10:30721971 MAP3K8 -0.44 -5.17 -0.42 9.28e-7 Inflammatory bowel disease; TGCT cis rs9324022 0.580 rs10151519 chr14:101175798 G/A cg18089426 chr14:101175970 NA 0.63 5.91 0.47 3.13e-8 Plateletcrit; TGCT cis rs921968 0.613 rs1427445 chr2:219555573 C/A cg02176678 chr2:219576539 TTLL4 -0.33 -4.46 -0.37 1.81e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs28595532 0.920 rs56227053 chr4:119772460 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT trans rs208520 0.507 rs3903670 chr6:66812183 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.08 -16.45 -0.83 5.75e-33 Exhaled nitric oxide output; TGCT cis rs80282103 0.867 rs12241632 chr10:1069070 A/T cg15531433 chr10:1639090 ADARB2 0.4 4.58 0.38 1.12e-5 Glomerular filtration rate (creatinine); TGCT cis rs9430161 0.579 rs7542158 chr1:11040193 G/A cg27631724 chr1:11040367 C1orf127 0.55 6.58 0.51 1.2e-9 Ewing sarcoma; TGCT cis rs1008375 1.000 rs1006722 chr4:17618713 A/G cg18681998 chr4:17616180 MED28 -0.96 -10.39 -0.68 1.43e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9357506 1.000 rs9296490 chr6:46315191 A/G cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs60871478 1.000 rs62432861 chr7:807649 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.6 0.38 1.04e-5 Cerebrospinal P-tau181p levels; TGCT cis rs4506170 0.887 rs72712339 chr8:128340554 C/T cg07795030 chr8:128802207 NA -0.21 -4.73 -0.39 5.95e-6 Prostate cancer; TGCT cis rs748404 0.631 rs7167882 chr15:43678663 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.63 0.38 9.05e-6 Lung cancer; TGCT trans rs77457752 0.567 rs12339494 chr9:13908934 T/C cg23609682 chr1:3070786 PRDM16 0.51 6.82 0.52 3.5e-10 Breast cancer; TGCT cis rs8180040 0.654 rs6766230 chr3:47196209 C/A cg27129171 chr3:47204927 SETD2 0.7 8.33 0.6 1.26e-13 Colorectal cancer; TGCT cis rs1532993 0.518 rs11097568 chr4:98597993 A/G cg05340658 chr4:99064831 C4orf37 -0.38 -4.49 -0.37 1.59e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs210152 0.588 rs1755040 chr6:33495175 A/C cg16739976 chr6:34101401 GRM4 -0.64 -5.27 -0.43 5.8e-7 Schizophrenia; TGCT cis rs939658 0.683 rs8024572 chr15:79465600 A/G cg17916960 chr15:79447300 NA 0.42 6.67 0.51 7.59e-10 Refractive error; TGCT cis rs8014204 0.604 rs11159109 chr14:75389074 G/A cg06637938 chr14:75390232 RPS6KL1 0.92 9.95 0.67 1.66e-17 Caffeine consumption; TGCT cis rs3008870 0.755 rs2755251 chr1:67496425 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.51 0.61 4.85e-14 Lymphocyte percentage of white cells; TGCT cis rs9811920 0.609 rs4479633 chr3:99654510 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.77 0.52 4.51e-10 Axial length; TGCT cis rs2072499 0.898 rs2736609 chr1:156202640 C/T cg25208724 chr1:156163844 SLC25A44 0.97 10.22 0.68 3.76e-18 Testicular germ cell tumor; TGCT cis rs11785400 0.793 rs3735993 chr8:143741170 G/A cg24634471 chr8:143751801 JRK 0.55 5.52 0.44 1.89e-7 Schizophrenia; TGCT cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg21171335 chr12:122356390 WDR66 0.6 6.57 0.51 1.22e-9 Mean corpuscular volume; TGCT trans rs17685 0.712 rs10952842 chr7:75780413 G/A cg19862616 chr7:65841803 NCRNA00174 0.53 9.19 0.64 1.13e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7523273 0.606 rs2796271 chr1:207941927 A/G cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs6598955 0.670 rs6676619 chr1:26539035 T/G cg01614726 chr1:26633154 UBXN11 0.49 4.69 0.39 7.09e-6 Obesity-related traits; TGCT cis rs2153535 0.580 rs9406162 chr6:8466196 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg19635926 chr16:89946313 TCF25 -0.28 -5.09 -0.42 1.28e-6 Skin colour saturation; TGCT cis rs7666738 0.606 rs10006414 chr4:99101401 T/C cg17366294 chr4:99064904 C4orf37 0.53 4.9 0.4 2.89e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs9951602 0.512 rs61021837 chr18:76648210 A/C cg02800362 chr5:177631904 HNRNPAB 1.15 12.91 0.76 1.08e-24 Obesity-related traits; TGCT cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.79 -0.39 4.72e-6 Coronary artery disease; TGCT cis rs11648796 0.757 rs66649828 chr16:766078 A/G cg00908189 chr16:619842 PIGQ 0.66 5.39 0.44 3.41e-7 Height; TGCT cis rs4478858 0.684 rs16834336 chr1:31751512 G/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs1158570 0.500 rs2554369 chr8:131314047 C/T cg16277922 chr8:131349729 ASAP1 0.46 5.9 0.47 3.31e-8 Platelet count; TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg22166914 chr1:53195759 ZYG11B 0.3 4.87 0.4 3.29e-6 Monocyte count; TGCT cis rs9913156 0.841 rs72824957 chr17:4590496 C/T cg00122941 chr17:4613640 ARRB2 0.88 7.63 0.57 5.46e-12 Lymphocyte counts; TGCT cis rs1215050 0.740 rs9994227 chr4:98767094 T/G cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7178572 0.568 rs12914345 chr15:77670401 A/C cg22256960 chr15:77711686 NA -0.86 -8.87 -0.62 6.51e-15 Type 2 diabetes; TGCT cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs11120822 0.814 rs6656691 chr1:7122453 C/G cg20434152 chr1:7120926 CAMTA1 -0.29 -4.58 -0.38 1.11e-5 Stearic acid (18:0) levels; TGCT cis rs853679 0.607 rs200489 chr6:27798257 T/C cg10876282 chr6:28092338 ZSCAN16 0.76 4.47 0.37 1.73e-5 Depression; TGCT cis rs68170813 0.559 rs74925723 chr7:106954536 G/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs10461617 0.541 rs860581 chr5:56150537 A/G cg24531977 chr5:56204891 C5orf35 -0.75 -5.9 -0.47 3.17e-8 Type 2 diabetes; TGCT cis rs9372498 0.536 rs9320656 chr6:118894468 A/G cg07617317 chr6:118971624 C6orf204 -0.5 -5.32 -0.43 4.71e-7 Diastolic blood pressure; TGCT cis rs7666738 0.606 rs7663216 chr4:99088385 A/C cg18180107 chr4:99064573 C4orf37 0.52 4.6 0.38 1.05e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs11031096 0.782 rs4910904 chr11:4165529 C/T cg18678763 chr11:4115507 RRM1 0.48 6.09 0.48 1.32e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs514406 0.584 rs12095247 chr1:53193796 A/C cg25767906 chr1:53392781 SCP2 0.46 5.02 0.41 1.76e-6 Monocyte count; TGCT cis rs7542091 0.669 rs11119357 chr1:210042382 C/T cg23283495 chr1:209979779 IRF6 0.56 5.6 0.45 1.3e-7 Monobrow; TGCT cis rs903263 0.901 rs11163913 chr1:84651183 G/T cg09664975 chr1:84543551 PRKACB 0.49 4.57 0.38 1.17e-5 Breast cancer (male); TGCT cis rs36051895 0.623 rs12351715 chr9:5262349 A/G cg02405213 chr9:5042618 JAK2 -0.68 -8.37 -0.6 1.02e-13 Pediatric autoimmune diseases; TGCT cis rs1347297 0.666 rs4404314 chr2:179250840 G/A cg03991736 chr2:179345203 MIR548N;PLEKHA3 -0.49 -4.51 -0.38 1.46e-5 Alzheimer disease and age of onset; TGCT cis rs75229567 0.618 rs78294090 chr12:70209959 G/T cg10114359 chr12:70132523 RAB3IP 1.35 6.68 0.51 7.19e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs2594989 0.943 rs2442780 chr3:11510568 A/G cg26283222 chr3:11613257 VGLL4 -0.21 -4.54 -0.38 1.31e-5 Circulating chemerin levels; TGCT cis rs6840360 0.667 rs2709832 chr4:152379394 C/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.804 rs4845678 chr1:154853295 A/G cg06221963 chr1:154839813 KCNN3 -0.75 -12.79 -0.75 2.05e-24 Prostate cancer; TGCT cis rs2594989 1.000 rs346082 chr3:11329216 C/G cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs362272 0.545 rs2748447 chr4:3337831 G/A cg06533319 chr4:3265114 C4orf44 -0.28 -5.69 -0.46 8.63e-8 Serum sulfate level; TGCT cis rs6978712 1.000 rs6961380 chr7:127148072 T/A cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs362272 0.545 rs2236052 chr4:3318413 C/T cg18352616 chr4:3374830 RGS12 -0.25 -5.09 -0.42 1.3e-6 Serum sulfate level; TGCT cis rs13191362 0.507 rs2023036 chr6:163122736 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.6 5.77 0.46 6.04e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs116095464 0.614 rs56299325 chr5:220594 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs981844 1.000 rs116588966 chr4:154664794 T/C cg14289246 chr4:154710475 SFRP2 1.0 8.25 0.6 1.96e-13 Response to statins (LDL cholesterol change); TGCT cis rs7264396 0.790 rs6060519 chr20:34217383 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.67 -0.39 7.62e-6 Total cholesterol levels; TGCT cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs921968 0.643 rs585859 chr2:219383121 C/T cg02176678 chr2:219576539 TTLL4 0.39 5.95 0.47 2.51e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs7729723 0.533 rs6596435 chr5:137827361 C/G cg19169342 chr5:137827400 NA 0.33 4.6 0.38 1.03e-5 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs7267979 0.933 rs11699203 chr20:25435169 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6912958 0.712 rs9444525 chr6:88324142 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -5.2 -0.42 7.9e-7 Monocyte percentage of white cells; TGCT cis rs3749237 0.595 rs11130199 chr3:49538799 T/C cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs3780378 0.967 rs7023146 chr9:5040163 G/A cg02405213 chr9:5042618 JAK2 -0.59 -7.69 -0.57 3.87e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs60843830 1.000 rs7566279 chr2:281178 C/G cg00108164 chr2:264199 ACP1;SH3YL1 0.69 6.44 0.5 2.41e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7584330 0.868 rs67071074 chr2:238395429 T/C cg14458575 chr2:238380390 NA 0.56 8.29 0.6 1.61e-13 Prostate cancer; TGCT cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs7605378 1.000 rs10194076 chr2:200677663 T/C cg17644776 chr2:200775616 C2orf69 0.26 5.1 0.42 1.25e-6 Osteoporosis; TGCT cis rs2688608 0.592 rs12253429 chr10:75496161 C/G cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs2535633 0.631 rs2581803 chr3:52994981 G/A cg10802521 chr3:52805072 NEK4 0.53 5.7 0.46 8.42e-8 Body mass index; TGCT cis rs9527 0.662 rs10786714 chr10:104598606 G/C cg04362960 chr10:104952993 NT5C2 0.63 5.36 0.43 3.99e-7 Arsenic metabolism; TGCT cis rs736408 0.812 rs4687654 chr3:52827566 G/A cg07507251 chr3:52567010 NT5DC2 0.41 5.46 0.44 2.46e-7 Bipolar disorder; TGCT cis rs10946940 0.965 rs62401383 chr6:27564547 C/T cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.73 -0.39 6.01e-6 Systemic lupus erythematosus; TGCT cis rs6750047 0.756 rs336038 chr2:38260750 C/G cg07380506 chr2:38303506 CYP1B1 0.55 4.98 0.41 2.08e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs4478858 0.611 rs10914338 chr1:31733782 T/A cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs7552404 0.889 rs380075 chr1:76106961 T/A cg03433033 chr1:76189801 ACADM -0.84 -10.07 -0.67 8.46e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs295140 0.624 rs10445790 chr2:201078088 T/C cg04283868 chr2:201171347 SPATS2L 0.54 5.36 0.43 3.85e-7 QT interval; TGCT cis rs9325144 0.560 rs7980358 chr12:38640396 C/G cg26384229 chr12:38710491 ALG10B 0.67 6.12 0.48 1.14e-8 Morning vs. evening chronotype; TGCT cis rs9921338 0.961 rs4780357 chr16:11370971 G/A cg00044050 chr16:11439710 C16orf75 -0.91 -6.23 -0.49 6.61e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4523957 0.651 rs9906705 chr17:2063714 T/G cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1371867 0.875 rs1788174 chr8:101330957 C/G cg06636551 chr8:101224915 SPAG1 0.48 6.51 0.5 1.7e-9 Atrioventricular conduction; TGCT cis rs2742234 0.955 rs2435384 chr10:43673731 G/T cg02780029 chr10:43622663 RET -0.26 -4.94 -0.41 2.49e-6 Hirschsprung disease; TGCT cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg21724239 chr8:58056113 NA 0.4 4.88 0.4 3.13e-6 Developmental language disorder (linguistic errors); TGCT cis rs7677751 0.806 rs4864862 chr4:55100489 G/A cg17187183 chr4:55093834 PDGFRA 0.56 7.13 0.54 7.37e-11 Corneal astigmatism; TGCT cis rs7208859 0.623 rs11658022 chr17:29085359 A/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.66e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4851254 0.920 rs11123808 chr2:100750750 A/C cg23118464 chr2:100721844 AFF3 0.74 5.52 0.44 1.86e-7 Intelligence (multi-trait analysis); TGCT cis rs4665809 1.000 rs1550381 chr2:26266946 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.22 -0.49 7.14e-9 Gut microbiome composition (summer); TGCT cis rs8077889 1.000 rs8077889 chr17:41878166 G/T cg26893861 chr17:41843967 DUSP3 -1.06 -12.33 -0.74 2.74e-23 Triglycerides; TGCT cis rs7226408 0.901 rs11081986 chr18:34683307 T/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg11494091 chr17:61959527 GH2 -0.6 -16.09 -0.82 3.89e-32 Prudent dietary pattern; TGCT cis rs7599312 0.534 rs10180824 chr2:213407975 G/A cg20637307 chr2:213403960 ERBB4 0.92 11.46 0.72 3.54e-21 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs35146811 0.696 rs1727124 chr7:99804104 T/G cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.4 2.61e-6 Coronary artery disease; TGCT cis rs763014 0.931 rs7192508 chr16:630367 C/T cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs7095607 1.000 rs12780285 chr10:69958749 C/T cg18986048 chr10:69913749 MYPN 0.46 5.0 0.41 1.91e-6 Lung function (FVC); TGCT cis rs2013441 1.000 rs2526490 chr17:20097526 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs17001868 0.568 rs470113 chr22:40729614 A/G cg07138101 chr22:40742427 ADSL 0.71 5.51 0.44 2.02e-7 Mammographic density (dense area); TGCT cis rs9911578 1.000 rs7342903 chr17:56914588 C/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs3803170 0.513 rs10849944 chr12:111825389 C/T cg10833066 chr12:111807467 FAM109A -0.36 -5.41 -0.44 3.09e-7 Mean corpuscular hemoglobin; TGCT cis rs858239 0.665 rs6964665 chr7:23211352 G/A cg05602783 chr7:23145260 KLHL7 -0.68 -5.52 -0.44 1.91e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1008375 1.000 rs2872959 chr4:17677163 G/A cg16339924 chr4:17578868 LAP3 -0.62 -5.11 -0.42 1.19e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs60871478 1.000 rs62432251 chr7:801855 T/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.45 4.56 0.38 1.21e-5 Cerebrospinal P-tau181p levels; TGCT cis rs6835098 0.961 rs2877748 chr4:174102397 G/A cg08422745 chr4:174089978 GALNT7 -0.9 -10.08 -0.67 7.91e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs10751667 0.643 rs10794343 chr11:925493 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.69e-13 Alzheimer's disease (late onset); TGCT cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg10117171 chr1:25599238 RHD -0.32 -5.17 -0.42 9e-7 Erythrocyte sedimentation rate; TGCT cis rs1801251 1.000 rs13003675 chr2:233584109 C/T cg08000102 chr2:233561755 GIGYF2 0.63 6.51 0.5 1.72e-9 Coronary artery disease; TGCT cis rs2980439 0.818 rs2948300 chr8:8106508 C/T cg15462221 chr8:8086144 FLJ10661 -0.55 -4.97 -0.41 2.17e-6 Neuroticism; TGCT cis rs7959452 0.590 rs11177628 chr12:69765421 G/A cg14784868 chr12:69753453 YEATS4 0.83 8.85 0.62 7.59e-15 Blood protein levels; TGCT cis rs9807989 0.507 rs2310300 chr2:103049074 A/G cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs3774830 0.748 rs17367445 chr4:5464903 C/T cg26943120 chr4:5472116 STK32B 0.22 4.82 0.4 4.15e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs2727020 0.729 rs6485965 chr11:49166730 C/T cg15704280 chr7:45808275 SEPT13 0.68 7.46 0.56 1.3e-11 Coronary artery disease; TGCT cis rs3796352 1.000 rs116616340 chr3:53132371 C/G cg15956490 chr3:53032818 SFMBT1 0.54 6.37 0.5 3.42e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs875971 0.862 rs801206 chr7:66021966 C/G cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs3749237 0.964 rs2234385 chr3:49846041 G/A cg07636037 chr3:49044803 WDR6 0.61 5.41 0.44 3.08e-7 Resting heart rate; TGCT cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg08392591 chr16:89556376 ANKRD11 0.57 5.4 0.44 3.2e-7 Multiple myeloma (IgH translocation); TGCT cis rs7809950 0.911 rs7778250 chr7:107224565 C/A cg23024343 chr7:107201750 COG5 0.33 5.13 0.42 1.09e-6 Coronary artery disease; TGCT cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg24846343 chr22:24311635 DDTL 0.23 5.85 0.46 4.19e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2847281 0.614 rs2847261 chr18:12775296 A/T cg23598886 chr18:12777645 NA 0.37 4.69 0.39 7.07e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs17767294 0.708 rs34957169 chr6:27879397 T/C cg08851530 chr6:28072375 NA 1.53 7.17 0.54 6.02e-11 Parkinson's disease; TGCT cis rs9383153 0.793 rs2016498 chr6:16344914 C/T cg10975897 chr6:15504844 JARID2 0.77 4.85 0.4 3.66e-6 Gambling; TGCT cis rs9653442 0.866 rs12712065 chr2:100761105 C/G cg07810366 chr2:100720526 AFF3 -0.47 -8.0 -0.58 7.36e-13 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11719291 0.504 rs34571182 chr3:49209057 T/A cg07636037 chr3:49044803 WDR6 -1.02 -5.13 -0.42 1.09e-6 Cognitive function; TGCT cis rs911555 0.504 rs8021368 chr14:104074810 G/A cg26031613 chr14:104095156 KLC1 0.61 5.6 0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs2841277 0.509 rs11850949 chr14:105408827 A/C cg21017887 chr14:105400489 NA 0.4 5.55 0.45 1.65e-7 Rheumatoid arthritis; TGCT cis rs3733585 0.699 rs62294331 chr4:9959889 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7264396 0.790 rs2425115 chr20:34322418 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs6545883 0.929 rs7563678 chr2:61741811 C/T cg15711740 chr2:61764176 XPO1 0.53 4.84 0.4 3.82e-6 Tuberculosis; TGCT cis rs6546847 0.531 rs2567602 chr2:73985536 A/G cg07208825 chr2:73871855 ALMS1P 0.29 5.27 0.43 5.73e-7 Urinary metabolites (H-NMR features); TGCT cis rs4919044 0.799 rs56024810 chr10:94753313 G/A cg05127821 chr10:94822908 CYP26C1 -0.73 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs4144743 1.000 rs72823474 chr17:45321776 G/C cg18085866 chr17:45331354 ITGB3 -0.7 -4.67 -0.39 7.81e-6 Body mass index; TGCT cis rs2115630 0.805 rs8042926 chr15:85205454 T/A cg11189052 chr15:85197271 WDR73 -0.71 -7.25 -0.55 3.98e-11 P wave terminal force; TGCT cis rs7296418 0.922 rs1790134 chr12:123697898 T/C cg00376283 chr12:123451042 ABCB9 0.84 7.67 0.57 4.4e-12 Platelet count; TGCT cis rs8008758 0.517 rs1772024 chr14:101695220 A/C cg26224664 chr14:101693935 NA 0.33 7.32 0.55 2.69e-11 Body mass index (alcohol intake interaction); TGCT cis rs933688 0.639 rs332530 chr5:90789810 G/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.07 9.91 0.66 2.11e-17 Smoking behavior; TGCT cis rs77880822 0.562 rs6078405 chr20:1247246 T/C cg03932398 chr20:1206703 RAD21L1 0.81 5.23 0.42 7.11e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg22166914 chr1:53195759 ZYG11B 0.34 5.39 0.44 3.42e-7 Monocyte count; TGCT cis rs7714584 1.000 rs57406211 chr5:150170966 C/T cg22134413 chr5:150180641 NA 1.11 7.3 0.55 3.05e-11 Crohn's disease; TGCT cis rs13040088 1.000 rs2273412 chr20:61553802 G/A cg23096297 chr20:61557774 DIDO1 1.17 9.61 0.65 1.11e-16 Menopause (age at onset); TGCT cis rs12142240 0.698 rs1984490 chr1:46858734 C/T cg14993813 chr1:46806288 NSUN4 0.58 4.79 0.4 4.69e-6 Menopause (age at onset); TGCT cis rs7666738 0.830 rs7657490 chr4:99043973 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs807669 0.557 rs712958 chr22:19167409 T/C cg02655711 chr22:19163373 SLC25A1 0.32 6.55 0.51 1.38e-9 Metabolite levels; TGCT cis rs910316 0.967 rs175451 chr14:75589729 C/T cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.71e-6 Height; TGCT cis rs76788097 0.614 rs7151034 chr14:61820669 T/G cg10081469 chr14:61748336 TMEM30B -0.71 -4.96 -0.41 2.3e-6 Marginal zone lymphoma; TGCT cis rs2299587 0.554 rs11778309 chr8:17747433 T/C cg01800426 chr8:17659068 MTUS1 -0.58 -5.12 -0.42 1.16e-6 Economic and political preferences; TGCT cis rs1062177 1.000 rs892006 chr5:151180890 G/T cg12924095 chr5:151150029 G3BP1 0.36 5.12 0.42 1.11e-6 Preschool internalizing problems; TGCT cis rs9788682 0.948 rs905739 chr15:78845110 A/G cg24631222 chr15:78858424 CHRNA5 0.92 7.37 0.55 2.1e-11 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7914558 0.966 rs3758543 chr10:104944744 C/G cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.65e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12510870 0.599 rs13353732 chr4:74397154 A/G cg05868023 chr4:75230803 EREG 0.54 5.01 0.41 1.83e-6 Iris color (b* coordinate); TGCT cis rs644799 0.687 rs11021318 chr11:95522996 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.5 0.61 5.03e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs288326 0.561 rs77541378 chr2:183886271 C/A cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs9291683 0.546 rs13110307 chr4:10044364 T/C cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Bone mineral density; TGCT cis rs12142240 0.959 rs12137934 chr1:46728913 A/G cg14993813 chr1:46806288 NSUN4 -0.61 -4.92 -0.4 2.75e-6 Menopause (age at onset); TGCT cis rs453301 0.658 rs9329175 chr8:8866661 C/T cg15556689 chr8:8085844 FLJ10661 -0.58 -4.87 -0.4 3.32e-6 Joint mobility (Beighton score); TGCT cis rs526231 0.819 rs403214 chr5:102603701 A/G cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs9303401 0.614 rs8081058 chr17:57160513 G/C cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs3733585 0.699 rs6449177 chr4:9968050 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.49 -0.5 1.85e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6835098 0.608 rs2332668 chr4:174163360 A/G cg08422745 chr4:174089978 GALNT7 -0.78 -8.44 -0.6 7.19e-14 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs236907 0.814 rs2232825 chr1:171763549 C/T cg20598894 chr1:171756153 METTL13 -0.22 -5.05 -0.41 1.53e-6 Mean platelet volume; TGCT cis rs4780401 0.588 rs1050069 chr16:11769963 C/T cg01061890 chr16:11836724 TXNDC11 -0.46 -4.52 -0.38 1.45e-5 Rheumatoid arthritis; TGCT cis rs1801251 1.000 rs2675971 chr2:233726154 A/G cg08000102 chr2:233561755 GIGYF2 -0.64 -6.45 -0.5 2.24e-9 Coronary artery disease; TGCT cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs7246657 0.943 rs6508711 chr19:37815134 G/T cg18154014 chr19:37997991 ZNF793 0.74 5.08 0.42 1.34e-6 Coronary artery calcification; TGCT cis rs9948 0.748 rs62156223 chr2:97412167 T/C cg01990225 chr2:97406019 LMAN2L -1.0 -5.09 -0.42 1.31e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs3087591 0.960 rs9896041 chr17:29571326 C/G cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.51 -0.56 1.01e-11 Hip circumference; TGCT cis rs4081724 0.565 rs118046236 chr19:33807105 G/A cg18823272 chr19:34111733 CHST8 0.42 4.7 0.39 6.85e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs79349575 0.681 rs56080003 chr17:47019049 A/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs1790761 0.559 rs10896190 chr11:67406123 T/C cg08355456 chr11:67383691 NA 0.3 4.55 0.38 1.26e-5 Mean corpuscular volume; TGCT cis rs7659604 0.539 rs11731917 chr4:122783233 G/A cg06713675 chr4:122721982 EXOSC9 -0.66 -8.76 -0.62 1.24e-14 Type 2 diabetes; TGCT cis rs9653442 0.564 rs11902705 chr2:100795207 A/G cg07810366 chr2:100720526 AFF3 0.34 5.03 0.41 1.69e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10972341 0.874 rs7028146 chr9:35150228 G/A cg00812861 chr9:35114699 KIAA1539 0.33 5.11 0.42 1.21e-6 Weight; TGCT cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg20637647 chr7:64974828 NA 0.99 5.12 0.42 1.14e-6 Diabetic kidney disease; TGCT cis rs6430585 0.527 rs7592050 chr2:136459227 C/T cg07169764 chr2:136633963 MCM6 -1.01 -9.4 -0.64 3.64e-16 Corneal structure; TGCT cis rs228437 0.565 rs6569956 chr6:134939428 C/T cg09872934 chr6:134495829 SGK1 -0.53 -4.6 -0.38 1.03e-5 Melanoma; TGCT cis rs28595532 0.920 rs115242199 chr4:119728652 A/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs9473924 0.542 rs2857501 chr6:50797286 A/G cg14470998 chr6:50812995 TFAP2B 1.33 7.94 0.58 1.03e-12 Body mass index; TGCT cis rs1667284 0.967 rs1791221 chr18:29219891 T/C cg15259973 chr18:29078565 DSG2 0.53 5.19 0.42 8.27e-7 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg22618164 chr12:122356400 WDR66 0.52 4.79 0.4 4.67e-6 Mean corpuscular volume; TGCT cis rs6687430 0.526 rs12120962 chr1:10609505 G/A cg17425144 chr1:10567563 PEX14 0.5 5.71 0.46 7.93e-8 Hand grip strength; TGCT cis rs7267979 1.000 rs910997 chr20:25267301 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6088590 1.000 rs2180276 chr20:33360785 T/A cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT cis rs2485376 0.842 rs1056890 chr10:104162770 G/A cg26089160 chr10:104170217 PSD 0.52 5.09 0.42 1.3e-6 QT interval; TGCT cis rs559928 0.606 rs55970968 chr11:63961433 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.57 0.38 1.18e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs8014204 0.839 rs6574197 chr14:75331487 A/G cg06637938 chr14:75390232 RPS6KL1 -0.77 -7.49 -0.56 1.14e-11 Caffeine consumption; TGCT cis rs3820928 0.618 rs2141828 chr2:227922470 T/C cg11843606 chr2:227700838 RHBDD1 -0.52 -4.69 -0.39 7.13e-6 Pulmonary function; TGCT cis rs7666738 0.612 rs6830172 chr4:99093947 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.67 0.45 9.42e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs806215 0.951 rs327510 chr7:127257894 G/A cg25922125 chr7:127225783 GCC1 0.48 4.98 0.41 2.06e-6 Type 2 diabetes; TGCT cis rs7267979 0.903 rs6050481 chr20:25224580 C/T cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs344364 0.511 rs1657132 chr16:1949924 C/T cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs6582630 0.555 rs4601853 chr12:38435569 G/A cg13010199 chr12:38710504 ALG10B 0.59 4.79 0.4 4.67e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6952808 0.564 rs73038441 chr7:2139286 T/C cg22963979 chr7:1858916 MAD1L1 -0.4 -6.44 -0.5 2.44e-9 Bipolar disorder and schizophrenia; TGCT cis rs9926296 0.572 rs8047581 chr16:89884502 C/T cg03388025 chr16:89894329 SPIRE2 0.35 5.3 0.43 5.05e-7 Vitiligo; TGCT cis rs12950390 0.853 rs28589850 chr17:45855713 A/G cg24803719 chr17:45855879 NA -0.48 -4.93 -0.4 2.62e-6 IgG glycosylation; TGCT cis rs9677476 1.000 rs6711312 chr2:232122348 T/C cg07929768 chr2:232055508 NA 0.3 4.44 0.37 1.97e-5 Food antigen IgG levels; TGCT cis rs11098499 0.909 rs10002083 chr4:120311152 C/T cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs9916302 0.904 rs587343 chr17:37440603 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.93 -0.4 2.59e-6 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs732299 chr4:98995389 C/T cg17366294 chr4:99064904 C4orf37 0.68 6.96 0.53 1.75e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs17401966 0.540 rs6674949 chr1:10458480 A/G cg19773385 chr1:10388646 KIF1B -0.22 -5.38 -0.44 3.55e-7 Hepatocellular carcinoma; TGCT cis rs208515 0.525 rs10944871 chr6:66690306 A/G cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs9733 0.596 rs3087960 chr1:150620569 C/G cg04414720 chr1:150670196 GOLPH3L 0.39 4.95 0.41 2.39e-6 Tonsillectomy; TGCT cis rs10423674 0.526 rs11668545 chr19:18829529 C/T cg14292368 chr19:18793705 CRTC1 -0.52 -4.73 -0.39 6.06e-6 Menarche (age at onset); TGCT cis rs9388451 0.587 rs1739385 chr6:126099939 G/A cg05901451 chr6:126070800 HEY2 -0.92 -11.38 -0.71 5.49e-21 Brugada syndrome; TGCT cis rs1670533 1.000 rs935970 chr4:1045323 C/G cg20887711 chr4:1340912 KIAA1530 -0.71 -5.64 -0.45 1.07e-7 Recombination rate (females); TGCT cis rs713587 0.934 rs6738433 chr2:25159501 G/C cg01884057 chr2:25150051 NA 0.39 7.96 0.58 9.32e-13 Body mass index in non-asthmatics; TGCT cis rs9443645 0.836 rs9352676 chr6:79629999 A/G cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7091068 0.522 rs866674 chr10:95487515 A/G cg20715218 chr10:95462985 C10orf4 0.5 4.88 0.4 3.13e-6 Urinary tract infection frequency; TGCT cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg06640241 chr16:89574553 SPG7 0.76 8.59 0.61 3.06e-14 Multiple myeloma (IgH translocation); TGCT cis rs5750830 0.649 rs5750818 chr22:39820885 A/G cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs35160687 0.901 rs6713456 chr2:86507653 T/A cg27135286 chr2:85751921 NA 0.38 4.46 0.37 1.82e-5 Night sleep phenotypes; TGCT cis rs739401 0.611 rs401707 chr11:3050965 T/C cg05729581 chr11:3078854 CARS -0.55 -5.15 -0.42 9.85e-7 Longevity; TGCT cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg11890956 chr21:40555474 PSMG1 1.09 11.95 0.73 2.27e-22 Cognitive function; TGCT cis rs2201728 0.967 rs3749551 chr4:100221551 C/T cg07219303 chr4:100140905 ADH6 -0.35 -5.14 -0.42 1.04e-6 Cardiac Troponin-T levels; TGCT cis rs9611565 0.512 rs139562 chr22:42196684 G/C cg03806693 chr22:41940476 POLR3H -0.99 -9.85 -0.66 2.9e-17 Vitiligo; TGCT cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs514406 0.683 rs6588440 chr1:53209587 C/T cg25767906 chr1:53392781 SCP2 0.46 5.1 0.42 1.23e-6 Monocyte count; TGCT cis rs1538970 1.000 rs1538970 chr1:45847562 G/A cg05343316 chr1:45956843 TESK2 0.65 5.18 0.42 8.79e-7 Platelet count; TGCT cis rs10510102 0.872 rs7906271 chr10:123707722 C/T cg23691251 chr10:123688108 ATE1 0.61 4.71 0.39 6.49e-6 Breast cancer; TGCT cis rs12477438 0.798 rs13414153 chr2:99624748 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.79 -7.94 -0.58 1.06e-12 Chronic sinus infection; TGCT cis rs9362426 0.708 rs4707367 chr6:88101188 A/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.5 -5.81 -0.46 4.86e-8 Depressive episodes in bipolar disorder; TGCT cis rs228437 0.565 rs7749820 chr6:134961923 C/T cg09872934 chr6:134495829 SGK1 -0.56 -4.74 -0.39 5.69e-6 Melanoma; TGCT cis rs7246657 0.943 rs4452075 chr19:37879589 A/G cg03233940 chr19:37894644 NA -0.35 -4.54 -0.38 1.3e-5 Coronary artery calcification; TGCT cis rs67478160 0.643 rs1535098 chr14:104216513 T/A cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs9926296 0.712 rs258319 chr16:89732024 A/T cg26513180 chr16:89883248 FANCA -0.67 -6.23 -0.49 6.68e-9 Vitiligo; TGCT cis rs3796352 1.000 rs11707780 chr3:53084326 A/G cg27565382 chr3:53032988 SFMBT1 -0.4 -4.63 -0.38 9.09e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs17376456 0.569 rs17083377 chr5:93164870 C/G cg21475434 chr5:93447410 FAM172A 0.66 5.2 0.42 8.03e-7 Diabetic retinopathy; TGCT cis rs28595532 1.000 rs17323012 chr4:119605671 A/G cg21605333 chr4:119757512 SEC24D 1.37 7.28 0.55 3.31e-11 Cannabis dependence symptom count; TGCT cis rs7917772 0.560 rs3862030 chr10:104327584 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12049351 0.774 rs12066463 chr1:229669287 C/T cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.05 0.48 1.61e-8 Bipolar disorder; TGCT trans rs551517 0.541 rs580721 chr9:113645310 A/G cg18410444 chr5:89825535 LYSMD3 0.68 6.81 0.52 3.77e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs1008375 0.932 rs6449315 chr4:17590219 A/G cg10189774 chr4:17578691 LAP3 0.61 5.28 0.43 5.6e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1814175 0.588 rs1721994 chr11:49914050 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs7647973 0.925 rs6769821 chr3:49244657 G/A cg06212747 chr3:49208901 KLHDC8B 0.59 4.71 0.39 6.39e-6 Menarche (age at onset); TGCT cis rs6424115 0.546 rs35993651 chr1:24180613 C/G cg15997130 chr1:24165203 NA -0.91 -10.51 -0.69 7.36e-19 Immature fraction of reticulocytes; TGCT cis rs2289583 0.503 rs113742359 chr15:75261643 A/G cg10253484 chr15:75165896 SCAMP2 0.58 5.23 0.43 6.95e-7 Systemic lupus erythematosus; TGCT cis rs4711350 0.734 rs7739273 chr6:33758065 G/A cg18005901 chr6:33739558 LEMD2 -0.59 -6.61 -0.51 1.01e-9 Schizophrenia; TGCT cis rs4654899 1.000 rs10916937 chr1:21439785 A/G cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7917772 0.619 rs2251772 chr10:104470918 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.68 5.69 0.46 8.52e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs877282 0.786 rs11253392 chr10:788768 G/A cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg22920501 chr2:26401640 FAM59B -0.8 -6.34 -0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs2762353 0.603 rs4145221 chr6:25763192 A/G cg03517284 chr6:25882590 NA 0.53 5.18 0.42 8.57e-7 Blood metabolite levels; TGCT cis rs12765878 0.603 rs1570221 chr10:105656874 G/A cg11005552 chr10:105648138 OBFC1 -0.39 -6.02 -0.48 1.85e-8 Coronary artery disease; TGCT cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg09359103 chr1:154839909 KCNN3 -0.62 -11.25 -0.71 1.15e-20 Prostate cancer; TGCT cis rs62229266 0.654 rs62230787 chr21:37376480 A/G cg12218747 chr21:37451666 NA -0.2 -4.48 -0.37 1.67e-5 Mitral valve prolapse; TGCT cis rs10789491 0.953 rs1866770 chr1:47182468 G/T cg15501359 chr1:47185051 KIAA0494 0.81 8.34 0.6 1.19e-13 Response to hepatitis C treatment; TGCT cis rs76419734 0.850 rs10516529 chr4:106799316 G/T cg24545054 chr4:106630052 GSTCD;INTS12 -0.96 -4.54 -0.38 1.29e-5 Post bronchodilator FEV1; TGCT cis rs11605924 0.819 rs12805422 chr11:45839889 G/A ch.11.939596F chr11:45881766 CRY2 -0.36 -4.57 -0.38 1.18e-5 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs7914558 0.966 rs10786721 chr10:104654383 C/A cg04362960 chr10:104952993 NT5C2 0.58 5.16 0.42 9.65e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1797081 1.000 rs780634 chr10:16864327 T/G cg14835575 chr10:16859367 RSU1 0.42 4.9 0.4 2.91e-6 Platelet distribution width; TGCT cis rs2191566 1.000 rs2191566 chr19:44511389 A/C cg03039196 chr19:44506973 ZNF230 -0.54 -4.7 -0.39 6.79e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs6484504 0.512 rs2774402 chr11:31312897 G/C cg26647111 chr11:31128758 NA 0.32 4.64 0.38 8.82e-6 Red blood cell count; TGCT cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs7091068 0.536 rs503758 chr10:95406935 C/A cg20715218 chr10:95462985 C10orf4 -0.51 -5.65 -0.45 1.05e-7 Urinary tract infection frequency; TGCT cis rs3796352 1.000 rs13072457 chr3:53102389 G/A cg07884673 chr3:53033167 SFMBT1 0.59 6.05 0.48 1.6e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs453301 0.653 rs11784393 chr8:8903134 C/T cg08975724 chr8:8085496 FLJ10661 0.58 4.89 0.4 3.02e-6 Joint mobility (Beighton score); TGCT cis rs3125734 0.633 rs6479792 chr10:63983264 T/G cg05499367 chr10:63213510 TMEM26 -0.33 -4.52 -0.38 1.4e-5 Rheumatoid arthritis; TGCT trans rs1005277 0.579 rs2008449 chr10:38414204 A/T cg17830980 chr10:43048298 ZNF37B 0.83 10.87 0.7 9.56e-20 Extrinsic epigenetic age acceleration; TGCT cis rs2268241 1.000 rs2268241 chr21:34781050 G/A cg14850771 chr21:34775459 IFNGR2 0.61 5.19 0.42 8.21e-7 Obesity-related traits; TGCT cis rs7633770 0.841 rs6442010 chr3:46669500 A/T cg11219411 chr3:46661640 NA 0.33 4.69 0.39 6.99e-6 Coronary artery disease; TGCT cis rs736408 0.581 rs3617 chr3:52833805 C/A cg07507251 chr3:52567010 NT5DC2 0.49 6.84 0.52 3.28e-10 Bipolar disorder; TGCT cis rs7223966 1.000 rs8075422 chr17:61804686 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.89 0.4 3.12e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.706 rs9944459 chr17:37484185 T/C cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs7647973 1.000 rs11720542 chr3:49357427 A/G cg06212747 chr3:49208901 KLHDC8B 0.59 4.72 0.39 6.22e-6 Menarche (age at onset); TGCT cis rs6690583 0.623 rs75918067 chr1:85453413 T/C cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg27454412 chr7:1067447 C7orf50 0.59 4.72 0.39 6.34e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs736408 0.608 rs35004449 chr3:52852897 G/T cg11645453 chr3:52864694 ITIH4 0.31 5.34 0.43 4.24e-7 Bipolar disorder; TGCT cis rs11105298 0.891 rs10858851 chr12:89830870 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -4.95 -0.41 2.36e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4409675 0.576 rs6598912 chr1:28233289 C/T cg23691781 chr1:28212827 C1orf38 0.25 5.31 0.43 4.87e-7 Corneal astigmatism; TGCT cis rs2289583 0.503 rs12050494 chr15:75260896 G/A cg10253484 chr15:75165896 SCAMP2 0.56 5.01 0.41 1.83e-6 Systemic lupus erythematosus; TGCT cis rs763014 0.931 rs7192508 chr16:630367 C/T cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs694739 0.734 rs663743 chr11:64107735 G/A cg23796481 chr11:64053134 BAD;GPR137 0.64 6.42 0.5 2.6e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs3813359 0.614 rs11154581 chr6:130770833 A/T cg25049486 chr6:130544510 SAMD3 0.43 5.58 0.45 1.46e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs8033133 0.602 rs12439159 chr15:25323874 T/C cg14481604 chr15:25334117 SNORD116-22 -0.23 -5.17 -0.42 9.25e-7 Blood osmolality (transformed sodium); TGCT cis rs9325144 0.600 rs10880934 chr12:38730455 C/T cg26384229 chr12:38710491 ALG10B -0.6 -5.5 -0.44 2.12e-7 Morning vs. evening chronotype; TGCT cis rs7681440 0.904 rs58864428 chr4:90766986 T/C cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs1062177 0.951 rs2915876 chr5:151150745 C/A cg12924095 chr5:151150029 G3BP1 0.36 5.06 0.41 1.49e-6 Preschool internalizing problems; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg21672276 chr3:44754072 ZNF502 -0.55 -6.31 -0.49 4.58e-9 Depressive symptoms; TGCT cis rs477895 0.713 rs2282490 chr11:63962152 T/C cg23719950 chr11:63933701 MACROD1 -0.71 -5.87 -0.47 3.82e-8 Mean platelet volume; TGCT cis rs1801251 0.778 rs778340 chr2:233734083 C/T cg25237894 chr2:233734115 C2orf82 -0.31 -6.2 -0.49 7.85e-9 Coronary artery disease; TGCT cis rs7769051 0.808 rs1467403 chr6:133089952 T/A cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs11585357 0.947 rs3003441 chr1:17611869 C/T cg08277548 chr1:17600880 PADI3 0.97 9.95 0.67 1.7e-17 Hair shape; TGCT cis rs669446 0.528 rs4660743 chr1:44195404 C/T cg12908607 chr1:44402522 ARTN -0.62 -7.05 -0.53 1.11e-10 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg06481639 chr22:41940642 POLR3H 0.71 6.43 0.5 2.56e-9 Vitiligo; TGCT cis rs7829975 0.623 rs10087493 chr8:8373557 A/G cg08975724 chr8:8085496 FLJ10661 -0.6 -5.78 -0.46 5.68e-8 Mood instability; TGCT cis rs2204008 0.659 rs4002655 chr12:38169881 T/G cg26384229 chr12:38710491 ALG10B 0.86 7.68 0.57 4.17e-12 Bladder cancer; TGCT cis rs854765 0.647 rs2974998 chr17:17995619 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.68 7.1 0.54 8.35e-11 Total body bone mineral density; TGCT cis rs992157 0.560 rs6436047 chr2:219108913 A/C cg00012203 chr2:219082015 ARPC2 0.81 9.25 0.64 8.28e-16 Colorectal cancer; TGCT cis rs911555 0.723 rs12894652 chr14:103926024 A/G cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs9326248 0.906 rs171052 chr11:117081763 C/G cg26566898 chr11:117069891 TAGLN -0.37 -5.05 -0.41 1.51e-6 Blood protein levels; TGCT cis rs142518269 1 rs142518269 chr2:24087095 G/A cg08917208 chr2:24149416 ATAD2B 0.9 5.5 0.44 2.06e-7 Mean corpuscular hemoglobin; TGCT cis rs116095464 0.614 rs78905930 chr5:246560 G/A cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs9300255 0.679 rs4759409 chr12:123719585 G/C cg00376283 chr12:123451042 ABCB9 0.67 5.26 0.43 6.13e-7 Neutrophil percentage of white cells; TGCT cis rs7666738 0.830 rs6829567 chr4:99047340 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7681440 0.904 rs2870029 chr4:90772057 G/T cg26578617 chr4:90757533 SNCA -0.46 -4.73 -0.39 6.01e-6 Dementia with Lewy bodies; TGCT cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg17971929 chr21:40555470 PSMG1 0.96 8.49 0.61 5.2e-14 Cognitive function; TGCT cis rs9486719 1.000 rs12201449 chr6:96959382 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT trans rs11764590 0.950 rs55683212 chr7:2078855 G/C cg10840412 chr1:235813424 GNG4 0.95 6.94 0.53 1.97e-10 Neuroticism; TGCT cis rs782590 0.537 rs7575170 chr2:55886780 C/T cg03859395 chr2:55845619 SMEK2 -0.65 -5.3 -0.43 5.13e-7 Metabolic syndrome; TGCT cis rs9486715 0.838 rs9386473 chr6:96873341 C/A cg18709589 chr6:96969512 KIAA0776 0.77 7.5 0.56 1.09e-11 Headache; TGCT cis rs1801251 1.000 rs11679079 chr2:233612656 C/T cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs6860806 0.531 rs272887 chr5:131665713 A/G cg24060327 chr5:131705240 SLC22A5 -0.73 -7.83 -0.58 1.83e-12 Breast cancer; TGCT cis rs6683273 0.720 rs12566775 chr1:3226929 C/T cg17435683 chr1:3230609 PRDM16 -0.4 -4.53 -0.38 1.35e-5 QRS duration; TGCT cis rs200810 0.634 rs62422096 chr6:97991866 A/G cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.68 -4.65 -0.39 8.37e-6 Body mass index; TGCT cis rs7666738 0.830 rs969049 chr4:98988857 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7027203 0.797 rs4744294 chr9:96612114 C/G cg14598338 chr9:96623480 NA -0.61 -9.56 -0.65 1.44e-16 DNA methylation (variation); TGCT cis rs12039431 0.746 rs10908354 chr1:38014601 A/G cg17933807 chr1:38061675 GNL2 -0.8 -7.69 -0.57 3.84e-12 Epithelial ovarian cancer; TGCT cis rs4900538 0.855 rs72698597 chr14:102868633 C/T cg18135206 chr14:102964638 TECPR2 -0.2 -4.55 -0.38 1.24e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs8056742 0.818 rs12926508 chr16:85092892 C/T cg00229868 chr16:85520891 NA -0.34 -4.8 -0.4 4.39e-6 Amyotrophic lateral sclerosis; TGCT cis rs12134245 0.742 rs17501381 chr1:92003919 A/G cg02896835 chr1:92012615 NA -0.27 -4.59 -0.38 1.08e-5 Breast cancer; TGCT cis rs12188164 0.931 rs115554641 chr5:443236 C/G cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs6570726 0.791 rs1509213 chr6:145783360 G/A cg23711669 chr6:146136114 FBXO30 -0.89 -9.87 -0.66 2.55e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 1.000 rs1121091 chr4:17676386 A/C cg10189774 chr4:17578691 LAP3 0.53 5.0 0.41 1.91e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs708547 0.830 rs1713994 chr4:57868367 G/A cg25525207 chr4:57843836 C4orf14;POLR2B -0.55 -5.02 -0.41 1.74e-6 Response to bleomycin (chromatid breaks); TGCT cis rs7829975 0.502 rs11785183 chr8:8565957 G/A cg17143192 chr8:8559678 CLDN23 -0.51 -5.11 -0.42 1.17e-6 Mood instability; TGCT cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg12310025 chr6:25882481 NA -0.92 -8.92 -0.63 5.07e-15 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs447722 chr20:25443510 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg04944784 chr2:26401820 FAM59B -0.76 -6.34 -0.49 3.94e-9 Gut microbiome composition (summer); TGCT cis rs6860806 0.531 rs274556 chr5:131722075 A/G cg24060327 chr5:131705240 SLC22A5 0.77 8.48 0.61 5.57e-14 Breast cancer; TGCT cis rs10465746 0.935 rs4258241 chr1:84437929 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.23 0.49 6.49e-9 Obesity-related traits; TGCT cis rs7647973 0.710 rs34890793 chr3:49619493 C/T cg05785598 chr3:49045655 WDR6 0.4 4.62 0.38 9.42e-6 Menarche (age at onset); TGCT cis rs9303401 0.659 rs35828828 chr17:56718205 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.26 0.49 5.86e-9 Cognitive test performance; TGCT cis rs10779751 0.734 rs2791657 chr1:11128001 A/G cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs1215050 0.740 rs185468 chr4:98756242 C/T cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg08736216 chr1:53307985 ZYG11A -0.28 -5.73 -0.46 7.33e-8 Monocyte count; TGCT cis rs3125734 0.719 rs10821972 chr10:64043735 G/A cg09941381 chr10:64027924 RTKN2 -0.31 -4.52 -0.38 1.45e-5 Rheumatoid arthritis; TGCT cis rs13191362 0.507 rs2803051 chr6:163034979 G/A cg06582575 chr6:163149167 PACRG;PARK2 -0.58 -5.72 -0.46 7.5e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12220898 0.679 rs10745257 chr10:50473892 T/C cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.85e-5 Inflammatory biomarkers; TGCT cis rs67133203 0.659 rs224589 chr12:51399050 A/C cg01517968 chr12:52348879 ACVR1B -0.35 -4.52 -0.38 1.44e-5 Urinary tract infection frequency; TGCT cis rs7772486 0.686 rs9403739 chr6:146015357 A/G cg13319975 chr6:146136371 FBXO30 0.48 4.43 0.37 2.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs3020736 0.519 rs5996116 chr22:42517492 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs76878669 0.561 rs4930363 chr11:66169676 C/T cg18002602 chr11:66138449 SLC29A2 0.5 6.37 0.5 3.41e-9 Educational attainment (years of education); TGCT cis rs6490294 0.904 rs12579298 chr12:112394022 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs8177253 0.665 rs4525863 chr3:133436136 C/A cg11941060 chr3:133502564 NA -0.27 -5.38 -0.43 3.58e-7 Iron status biomarkers; TGCT cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg26531700 chr6:26746687 NA -0.54 -4.89 -0.4 3.07e-6 Intelligence (multi-trait analysis); TGCT cis rs10206020 0.879 rs72778007 chr2:1573178 C/T cg01028140 chr2:1542097 TPO -0.32 -4.99 -0.41 1.97e-6 IgG glycosylation; TGCT cis rs7119 0.717 rs62009071 chr15:77817886 C/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg22105103 chr4:187893119 NA 0.34 4.62 0.38 9.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs933688 1.000 rs2052553 chr5:90729906 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.97 8.61 0.61 2.82e-14 Smoking behavior; TGCT cis rs79349575 0.783 rs2112617 chr17:46977125 G/A cg26022315 chr17:47021804 SNF8 0.53 5.31 0.43 4.82e-7 Type 2 diabetes; TGCT cis rs6687430 0.526 rs6688558 chr1:10611403 A/G cg17425144 chr1:10567563 PEX14 0.51 5.99 0.47 2.06e-8 Hand grip strength; TGCT cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg12310025 chr6:25882481 NA -1.1 -14.2 -0.79 9.06e-28 Urate levels; TGCT cis rs13191362 0.507 rs2023038 chr6:163119280 C/G cg06582575 chr6:163149167 PACRG;PARK2 -0.56 -5.39 -0.44 3.43e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9393692 0.905 rs6931391 chr6:26279235 G/C cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.14e-9 Educational attainment; TGCT trans rs1814175 0.754 rs10219245 chr11:49645052 C/T cg11707556 chr5:10655725 ANKRD33B -0.38 -7.79 -0.57 2.3e-12 Height; TGCT cis rs2639990 1.000 rs2639990 chr18:72915551 T/C cg02750262 chr18:72916776 ZADH2 0.9 6.7 0.52 6.56e-10 Vascular endothelial growth factor levels; TGCT cis rs7662987 0.517 rs1311615 chr4:100012261 G/A cg12011299 chr4:100065546 ADH4 0.42 4.87 0.4 3.38e-6 Smoking initiation; TGCT cis rs875971 0.862 rs6955837 chr7:66043142 C/T cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs6121246 0.529 rs2889528 chr20:30210021 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs5771225 0.544 rs13055135 chr22:50672479 A/G cg16473166 chr22:50639996 SELO 0.57 4.71 0.39 6.57e-6 Late-onset Alzheimer's disease; TGCT cis rs9926296 0.605 rs3743859 chr16:89846050 A/G cg26513180 chr16:89883248 FANCA -1.06 -14.59 -0.79 1.13e-28 Vitiligo; TGCT cis rs36051895 0.553 rs16922773 chr9:5197436 T/G cg02405213 chr9:5042618 JAK2 -0.72 -8.66 -0.61 2.1e-14 Pediatric autoimmune diseases; TGCT cis rs11627546 0.615 rs57951641 chr14:70365341 G/A cg10496350 chr14:71275911 MAP3K9 -0.89 -4.5 -0.37 1.52e-5 Red blood cell traits; TGCT cis rs10883723 0.962 rs10883726 chr10:104236276 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 7.52 0.56 9.74e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs459571 0.959 rs416390 chr9:136908549 C/G cg13789015 chr9:136890014 NCRNA00094 -0.42 -7.81 -0.57 2.03e-12 Platelet distribution width; TGCT cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg06212747 chr3:49208901 KLHDC8B 0.67 6.36 0.5 3.57e-9 Menarche (age at onset); TGCT cis rs651907 0.535 rs11717638 chr3:101505468 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.41 4.6 0.38 1.03e-5 Blood metabolite levels; TGCT cis rs17401966 1.000 rs11576866 chr1:10414432 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.5 -0.37 1.57e-5 Hepatocellular carcinoma; TGCT cis rs6570726 0.818 rs9390338 chr6:145908265 A/G cg05347473 chr6:146136440 FBXO30 0.51 4.75 0.39 5.42e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs208515 0.556 rs10455193 chr6:66691456 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs28595532 0.920 rs115994240 chr4:119744622 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9733 0.596 rs34600506 chr1:150687808 C/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs7647973 0.925 rs7429661 chr3:49228800 G/A cg06212747 chr3:49208901 KLHDC8B 0.56 4.54 0.38 1.32e-5 Menarche (age at onset); TGCT trans rs916888 0.773 rs199534 chr17:44824213 T/G cg01341218 chr17:43662625 NA 1.11 9.15 0.63 1.43e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs427394 0.664 rs274701 chr5:6728707 C/A cg10857441 chr5:6722123 POLS -0.29 -7.24 -0.54 4.17e-11 Menopause (age at onset); TGCT cis rs7666738 0.830 rs62321598 chr4:99014237 C/T cg17366294 chr4:99064904 C4orf37 0.66 6.75 0.52 5.04e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs7741403 chr6:8530578 C/T cg23788917 chr6:8435910 SLC35B3 -0.6 -5.37 -0.43 3.79e-7 Motion sickness; TGCT cis rs651907 0.535 rs34743741 chr3:101532448 C/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.5 -0.5 1.8e-9 Colorectal cancer; TGCT cis rs9926296 0.572 rs8046872 chr16:89841552 T/C cg26513180 chr16:89883248 FANCA 0.72 7.02 0.53 1.3e-10 Vitiligo; TGCT cis rs6998277 1.000 rs35155104 chr8:103646559 G/T cg10187029 chr8:103597600 NA 0.48 6.26 0.49 5.81e-9 Migraine; TGCT cis rs7737716 0.500 rs57503789 chr5:118228863 A/G cg21035905 chr5:118964330 FAM170A 0.41 4.71 0.39 6.64e-6 Cerebrospinal P-tau181p levels;Cerebrospinal T-tau levels; TGCT cis rs4268898 0.662 rs2303291 chr2:24431184 C/T cg02683114 chr2:24398427 C2orf84 -0.25 -4.73 -0.39 6.03e-6 Asthma; TGCT cis rs13256369 0.851 rs13258283 chr8:8563630 T/C cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs554111 0.656 rs4654893 chr1:21305596 G/C cg01072550 chr1:21505969 NA 0.35 5.35 0.43 4.11e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg08736216 chr1:53307985 ZYG11A -0.24 -4.89 -0.4 3e-6 Monocyte count; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg07332563 chr6:291687 DUSP22 0.71 7.37 0.55 2.06e-11 Menopause (age at onset); TGCT cis rs35146811 0.589 rs1727142 chr7:99816179 T/C cg13334819 chr7:99746414 C7orf59 0.66 5.35 0.43 4.03e-7 Coronary artery disease; TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg10263370 chr3:44754102 ZNF502 -0.43 -5.14 -0.42 1.04e-6 Depressive symptoms; TGCT cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg21285383 chr16:89894308 SPIRE2 0.33 4.71 0.39 6.6e-6 Vitiligo; TGCT cis rs7552404 0.924 rs1146574 chr1:76202671 A/G cg10523679 chr1:76189770 ACADM 0.84 9.32 0.64 5.67e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.46 5.04 0.41 1.58e-6 Blood metabolite levels; TGCT cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg06238570 chr21:40685208 BRWD1 0.75 7.06 0.54 1.07e-10 Cognitive function; TGCT cis rs477895 0.838 rs12794145 chr11:64006484 C/T cg04317338 chr11:64019027 PLCB3 0.82 7.06 0.54 1.06e-10 Mean platelet volume; TGCT cis rs10504229 1.000 rs59843034 chr8:58195756 T/G cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs10501293 0.529 rs2902301 chr11:43093159 A/T cg03447554 chr11:43094025 NA -0.45 -7.65 -0.57 4.79e-12 Cognitive performance; TGCT trans rs7726839 0.540 rs55929359 chr5:595956 C/G cg11887960 chr12:57824829 NA 1.19 9.31 0.64 5.73e-16 Obesity-related traits; TGCT cis rs9399135 0.967 rs13191501 chr6:135366880 T/C cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs1401999 0.659 rs7622660 chr3:183753337 C/T cg01324343 chr3:183735012 ABCC5 0.75 8.92 0.63 5.1e-15 Anterior chamber depth; TGCT cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg26531700 chr6:26746687 NA 0.51 4.61 0.38 9.86e-6 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.790 rs55706012 chr6:26266311 A/C cg10795676 chr6:26370623 BTN3A2 -0.49 -4.46 -0.37 1.79e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT cis rs2204008 0.744 rs11514071 chr12:38392076 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.59 0.38 1.05e-5 Bladder cancer; TGCT cis rs6952808 0.601 rs3800882 chr7:2120758 G/A cg04267008 chr7:1944627 MAD1L1 -0.35 -4.72 -0.39 6.17e-6 Bipolar disorder and schizophrenia; TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg06873352 chr17:61820015 STRADA -0.57 -6.38 -0.5 3.21e-9 Prudent dietary pattern; TGCT cis rs12643440 0.538 rs970428 chr4:17136795 C/A cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs7302981 0.934 rs7279 chr12:50523947 A/G cg23855989 chr12:50355821 AQP5 -0.3 -4.44 -0.37 2e-5 Systolic blood pressure; TGCT cis rs60843830 0.964 rs17713879 chr2:254215 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.65 6.13 0.48 1.06e-8 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs422249 0.613 rs174465 chr11:61658800 C/T cg01500311 chr11:61656094 FADS3 0.34 6.51 0.5 1.72e-9 Trans fatty acid levels; TGCT cis rs2440129 1.000 rs2440129 chr17:6906571 C/G cg05215272 chr17:6899095 ALOX12 0.43 4.45 0.37 1.86e-5 Tonsillectomy; TGCT cis rs9906944 0.703 rs940088 chr17:47145848 T/C cg20966754 chr17:47091339 IGF2BP1 -0.47 -5.33 -0.43 4.46e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs9682041 0.627 rs11924474 chr3:170091333 T/G cg07589077 chr3:170072950 NA 0.26 4.53 0.38 1.36e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs3796352 1.000 rs34121720 chr3:53072167 C/T cg07884673 chr3:53033167 SFMBT1 0.6 6.24 0.49 6.25e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8031584 0.678 rs36047941 chr15:31159235 A/G cg08704250 chr15:31115839 NA -0.43 -6.31 -0.49 4.47e-9 Huntington's disease progression; TGCT trans rs66573146 0.901 rs7668802 chr4:6986236 T/A cg07817883 chr1:32538562 TMEM39B 1.76 8.28 0.6 1.7e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs11096990 0.656 rs2123028 chr4:39303479 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.46e-5 Cognitive function; TGCT cis rs7824557 0.569 rs2409718 chr8:11012977 C/T cg21775007 chr8:11205619 TDH -0.53 -5.01 -0.41 1.84e-6 Retinal vascular caliber; TGCT cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.56 0.45 1.58e-7 Height; TGCT cis rs7567389 0.600 rs11679414 chr2:128151003 G/A cg09760422 chr2:128146352 NA 0.38 4.94 0.41 2.43e-6 Self-rated health; TGCT cis rs7513165 0.935 rs12097666 chr1:204162212 A/G cg12731349 chr1:204159619 KISS1 0.48 5.41 0.44 3.1e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs6977660 0.714 rs10231980 chr7:19789383 C/G cg05791153 chr7:19748676 TWISTNB 0.88 5.05 0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs11148252 0.538 rs2408609 chr13:52714043 C/T cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.84e-8 Lewy body disease; TGCT cis rs9611565 0.559 rs8139993 chr22:41995335 T/C cg17554472 chr22:41940697 POLR3H -0.49 -5.15 -0.42 9.88e-7 Vitiligo; TGCT cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg06481639 chr22:41940642 POLR3H -0.75 -6.47 -0.5 2.1e-9 Vitiligo; TGCT cis rs60733400 0.644 rs28774982 chr1:2621352 C/G cg18854424 chr1:2615690 NA -0.44 -4.99 -0.41 2e-6 Multiple sclerosis; TGCT cis rs3820928 1.000 rs978909 chr2:227771389 A/C cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 8.93e-6 Pulmonary function; TGCT cis rs9811920 0.609 rs4244711 chr3:99657205 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.77 0.52 4.51e-10 Axial length; TGCT cis rs3733585 0.631 rs3822236 chr4:10119961 T/G cg00071950 chr4:10020882 SLC2A9 -0.51 -5.28 -0.43 5.7e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.830 rs17484890 chr4:99013778 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.53 0.44 1.79e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.59 5.3 0.43 5.06e-7 Height; TGCT cis rs9300255 0.602 rs1790126 chr12:123683563 C/T cg00376283 chr12:123451042 ABCB9 0.71 5.59 0.45 1.41e-7 Neutrophil percentage of white cells; TGCT cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg17971929 chr21:40555470 PSMG1 -0.55 -4.96 -0.41 2.25e-6 Menarche (age at onset); TGCT cis rs60871478 0.541 rs56964970 chr7:910791 G/C cg15782153 chr7:917662 C7orf20 0.57 5.12 0.42 1.14e-6 Cerebrospinal P-tau181p levels; TGCT cis rs6582630 0.555 rs7294313 chr12:38323603 G/A cg26384229 chr12:38710491 ALG10B -0.52 -4.49 -0.37 1.6e-5 Drug-induced liver injury (flucloxacillin); TGCT trans rs9295123 0.898 rs9347388 chr6:160572557 T/A cg22927510 chr22:50968328 TYMP -0.51 -6.82 -0.52 3.63e-10 Blood protein levels; TGCT cis rs2180341 1.000 rs9321073 chr6:127609691 C/T cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs2742417 0.603 rs13059502 chr3:45781380 A/G cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs57244997 0.932 rs73026582 chr6:162406460 C/T cg17173639 chr6:162384350 PARK2 -0.43 -4.66 -0.39 7.92e-6 Mosquito bite size; TGCT cis rs6977660 0.714 rs12386623 chr7:19791875 A/G cg07541023 chr7:19748670 TWISTNB -0.85 -4.84 -0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs2227564 0.620 rs3812637 chr10:75568846 C/T cg23231163 chr10:75533350 FUT11 -0.28 -4.62 -0.38 9.65e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs854765 0.583 rs4414547 chr17:17859052 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs7095607 0.704 rs6480309 chr10:69953066 G/A cg18986048 chr10:69913749 MYPN 0.58 6.79 0.52 4.14e-10 Lung function (FVC); TGCT cis rs6570726 0.764 rs376257 chr6:145862949 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs79057730 0.599 rs6944167 chr7:826274 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.64 5.98 0.47 2.17e-8 Initial pursuit acceleration; TGCT trans rs1814175 0.935 rs7925863 chr11:49615802 C/A cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs36051895 0.587 rs7848872 chr9:5197027 T/A cg02405213 chr9:5042618 JAK2 -0.72 -8.79 -0.62 1.04e-14 Pediatric autoimmune diseases; TGCT cis rs12681287 0.785 rs13263353 chr8:87244582 C/T cg27223183 chr8:87520930 FAM82B -0.8 -5.77 -0.46 5.94e-8 Caudate activity during reward; TGCT cis rs3540 0.513 rs2589974 chr15:90891566 C/T cg22089800 chr15:90895588 ZNF774 -0.82 -9.07 -0.63 2.21e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs6121246 0.865 rs6058421 chr20:30295013 G/C cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs17152411 0.652 rs10901842 chr10:126635262 C/T cg07906193 chr10:126599966 NA 0.28 4.45 0.37 1.91e-5 Height; TGCT cis rs1215050 0.765 rs588851 chr4:98678247 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.51 0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6933660 0.760 rs6904364 chr6:151754273 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.52 4.87 0.4 3.28e-6 Menarche (age at onset); TGCT trans rs4332037 0.539 rs34809719 chr7:2028968 G/T cg25206134 chr2:45395956 NA 0.97 7.33 0.55 2.6e-11 Bipolar disorder; TGCT cis rs2816062 0.813 rs6698315 chr1:18895806 A/G cg18795169 chr1:18902165 NA -0.58 -13.28 -0.77 1.36e-25 Urate levels in lean individuals; TGCT cis rs704 0.585 rs3093680 chr17:26664806 T/C cg10342447 chr17:26645325 TMEM97 -0.59 -5.72 -0.46 7.56e-8 Osteoprotegerin levels; TGCT cis rs9467711 0.790 rs35942569 chr6:26339131 A/G cg16898833 chr6:26189333 HIST1H4D 1.29 5.8 0.46 5.25e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs933688 1.000 rs10045280 chr5:90717675 T/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 10.02 0.67 1.13e-17 Smoking behavior; TGCT cis rs12477438 0.765 rs1115757 chr2:99660146 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs3849570 0.555 rs4452351 chr3:82007977 C/T cg07356753 chr3:81810745 GBE1 -0.62 -5.38 -0.44 3.5e-7 Waist circumference;Body mass index; TGCT cis rs8028182 0.636 rs11634863 chr15:75766672 C/A cg20655648 chr15:75932815 IMP3 0.58 4.51 0.38 1.48e-5 Sudden cardiac arrest; TGCT trans rs10506458 0.688 rs60936040 chr12:63416461 G/A cg22491629 chr6:157744540 C6orf35 -0.8 -6.96 -0.53 1.72e-10 Hemostatic factors and hematological phenotypes; TGCT cis rs11167764 1.000 rs3761757 chr5:141488219 A/C cg08523384 chr5:141488047 NDFIP1 -0.25 -5.37 -0.43 3.72e-7 Crohn's disease; TGCT cis rs597539 0.652 rs544370 chr11:68653232 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.3 0.6 1.46e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs68170813 0.559 rs11773514 chr7:106958469 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs7255045 0.788 rs8111370 chr19:12948864 G/T cg06537894 chr19:12978706 MAST1 -0.49 -4.44 -0.37 1.98e-5 Mean corpuscular volume; TGCT cis rs12477438 0.798 rs9808541 chr2:99642179 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs6665290 0.935 rs6670924 chr1:227196048 A/C cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs644799 1.000 rs472231 chr11:95532166 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.84 8.85 0.62 7.42e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6089829 0.925 rs6122087 chr20:61664553 T/C cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs67311347 1.000 rs7648952 chr3:40457038 C/T cg13683864 chr3:40499215 RPL14 1.04 10.79 0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs9473924 0.505 rs7753025 chr6:50858352 A/C cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs9880772 0.747 rs7621606 chr3:27819783 C/T cg21473142 chr3:27762095 EOMES -0.42 -4.53 -0.38 1.38e-5 Chronic lymphocytic leukemia;B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy); TGCT cis rs295140 1.000 rs10931899 chr2:201176901 A/G cg04283868 chr2:201171347 SPATS2L -0.65 -6.67 -0.51 7.73e-10 QT interval; TGCT cis rs28595532 0.748 rs72670248 chr4:119335536 A/C cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs981844 0.712 rs6855082 chr4:154754039 A/G cg14289246 chr4:154710475 SFRP2 -0.98 -8.82 -0.62 8.67e-15 Response to statins (LDL cholesterol change); TGCT cis rs3749237 0.964 rs2352975 chr3:49891885 T/C cg10152585 chr3:50297680 NA 0.52 4.7 0.39 6.83e-6 Resting heart rate; TGCT cis rs806215 0.547 rs17151377 chr7:127458009 G/T cg11539674 chr7:127291444 SND1 -0.34 -4.45 -0.37 1.9e-5 Type 2 diabetes; TGCT cis rs7264396 0.616 rs6142476 chr20:34581216 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.27 -4.9 -0.4 2.9e-6 Total cholesterol levels; TGCT cis rs9399137 0.507 rs4289677 chr6:135275485 A/G cg24558204 chr6:135376177 HBS1L 0.5 5.07 0.41 1.38e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT trans rs10435719 0.610 rs80269926 chr8:11790527 T/C cg15556689 chr8:8085844 FLJ10661 0.75 6.87 0.53 2.77e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs4746818 1.000 rs4284308 chr10:70884861 C/T cg04149295 chr10:70884716 VPS26A 0.75 5.31 0.43 4.84e-7 Left atrial antero-posterior diameter; TGCT cis rs2153535 0.580 rs6421949 chr6:8531769 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9733 0.596 rs34140753 chr1:150642583 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs9467773 0.967 rs1535276 chr6:26520941 T/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.520 rs6542863 chr2:99725138 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs112257498 1 rs112257498 chr2:190432985 C/T cg10752008 chr2:190445175 SLC40A1 -0.49 -4.59 -0.38 1.05e-5 Red blood cell count;Mean corpuscular hemoglobin; TGCT cis rs10875746 0.903 rs11168403 chr12:48484958 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT trans rs17685 0.672 rs55807301 chr7:75807401 C/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.83 0.62 8.1e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2293052 0.697 rs551846 chr12:117754060 G/A cg02962597 chr12:117799749 NOS1 0.26 4.62 0.38 9.57e-6 Schizophrenia; TGCT cis rs2469997 1.000 rs2470028 chr8:120365878 A/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs12620999 0.567 rs4663243 chr2:238102994 A/G cg23555395 chr2:238036564 NA -0.28 -4.97 -0.41 2.17e-6 Systemic lupus erythematosus; TGCT cis rs7178572 0.889 rs59153558 chr15:77806770 A/G cg22256960 chr15:77711686 NA -0.95 -10.73 -0.69 2.16e-19 Type 2 diabetes; TGCT cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg05025164 chr4:1340916 KIAA1530 0.8 6.69 0.51 7.02e-10 Longevity; TGCT cis rs9303401 0.614 rs34683543 chr17:56520036 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.6 6.27 0.49 5.37e-9 Cognitive test performance; TGCT cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs7769051 0.711 rs7758703 chr6:133085417 T/C cg07930552 chr6:133119739 C6orf192 0.9 4.67 0.39 7.86e-6 Type 2 diabetes nephropathy; TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg16145915 chr7:1198662 ZFAND2A -0.63 -8.86 -0.62 7.11e-15 Longevity;Endometriosis; TGCT cis rs2836974 0.666 rs12626405 chr21:40663121 G/T cg17971929 chr21:40555470 PSMG1 -0.7 -6.54 -0.51 1.44e-9 Cognitive function; TGCT cis rs854765 0.547 rs9912096 chr17:17896673 A/C cg09796270 chr17:17721594 SREBF1 0.25 5.04 0.41 1.61e-6 Total body bone mineral density; TGCT cis rs2718812 0.792 rs1006098 chr3:133411605 G/T cg08048268 chr3:133502702 NA 0.38 4.58 0.38 1.1e-5 Iron status biomarkers; TGCT cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg09904177 chr6:26538194 HMGN4 -0.61 -5.84 -0.46 4.38e-8 Intelligence (multi-trait analysis); TGCT cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg02187348 chr16:89574699 SPG7 0.61 6.57 0.51 1.25e-9 Multiple myeloma (IgH translocation); TGCT cis rs2302045 1.000 rs3796093 chr2:242039198 T/C cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs13256369 0.865 rs13282523 chr8:8577293 C/G cg17143192 chr8:8559678 CLDN23 0.61 5.77 0.46 5.94e-8 Obesity-related traits; TGCT cis rs739401 0.611 rs7394974 chr11:3038868 C/T cg25174290 chr11:3078921 CARS 0.47 4.68 0.39 7.52e-6 Longevity; TGCT cis rs11105298 0.891 rs10858900 chr12:89925081 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.95 -0.41 2.41e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg15556689 chr8:8085844 FLJ10661 -0.69 -6.48 -0.5 1.99e-9 Mood instability; TGCT cis rs12497850 0.864 rs4513485 chr3:49139966 G/A cg18654377 chr3:49208889 KLHDC8B -0.37 -4.69 -0.39 7.12e-6 Parkinson's disease; TGCT cis rs10949834 0.689 rs2269081 chr7:73519887 T/G cg07137043 chr7:73588983 EIF4H -0.83 -5.87 -0.47 3.69e-8 Verbal memory performance (residualized delayed recall change); TGCT cis rs11190604 1.000 rs2495760 chr10:102318771 T/C cg16342193 chr10:102329863 NA -0.41 -5.17 -0.42 9.26e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2120019 0.935 rs8042409 chr15:75350433 G/A cg11632617 chr15:75315747 PPCDC -0.32 -4.67 -0.39 7.58e-6 Blood trace element (Zn levels); TGCT cis rs7937682 0.632 rs11214009 chr11:111683142 T/C cg09085632 chr11:111637200 PPP2R1B 0.8 6.98 0.53 1.61e-10 Primary sclerosing cholangitis; TGCT cis rs34638657 0.518 rs4889467 chr16:82169385 C/T cg09439754 chr16:82129088 HSD17B2 -0.22 -4.54 -0.38 1.32e-5 Lung adenocarcinoma; TGCT cis rs6460942 0.915 rs6945067 chr7:12444731 A/C cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs3812831 0.695 rs10467349 chr13:114939441 A/G cg08824895 chr13:115047677 UPF3A 0.48 4.6 0.38 1.04e-5 Schizophrenia; TGCT cis rs7917772 0.582 rs10786685 chr10:104323103 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.57 5.63 0.45 1.13e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg13397359 chr6:42928475 GNMT 0.66 5.93 0.47 2.81e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs308447 0.576 rs10005301 chr4:123715055 A/G cg10495464 chr4:123653540 BBS12;LOC729338 -0.74 -8.39 -0.6 9.37e-14 Perceived unattractiveness to mosquitoes; TGCT cis rs854765 0.647 rs721669 chr17:18005073 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.7 7.22 0.54 4.53e-11 Total body bone mineral density; TGCT cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg00786635 chr1:25594202 NA 0.52 5.63 0.45 1.17e-7 Erythrocyte sedimentation rate; TGCT cis rs9916302 0.904 rs11078898 chr17:37536480 A/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.51e-6 Glomerular filtration rate (creatinine); TGCT cis rs7572733 0.534 rs2574832 chr2:198704818 T/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs6545883 0.929 rs2121660 chr2:61653058 T/C cg15711740 chr2:61764176 XPO1 0.54 4.9 0.4 2.89e-6 Tuberculosis; TGCT cis rs713587 0.691 rs754536 chr2:25176200 C/T cg01884057 chr2:25150051 NA -0.31 -5.93 -0.47 2.79e-8 Body mass index in non-asthmatics; TGCT cis rs1371867 0.555 rs2861348 chr8:101285074 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.8 -0.4 4.44e-6 Atrioventricular conduction; TGCT cis rs6975373 0.643 rs12540089 chr7:4446121 C/A cg04153130 chr7:4456396 NA 0.44 4.54 0.38 1.32e-5 Borderline personality disorder; TGCT cis rs4862750 0.881 rs6813866 chr4:187872161 T/G cg03452623 chr4:187889614 NA -0.36 -5.24 -0.43 6.6e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs35306767 0.903 rs7077278 chr10:911291 A/G cg20503657 chr10:835505 NA -0.73 -10.2 -0.68 4.09e-18 Eosinophil percentage of granulocytes; TGCT cis rs9914988 0.887 rs11652710 chr17:27145075 C/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs6430585 0.583 rs58116536 chr2:136585323 C/T cg07169764 chr2:136633963 MCM6 1.23 11.99 0.73 1.85e-22 Corneal structure; TGCT cis rs7772486 0.875 rs2180192 chr6:146322284 T/C cg13319975 chr6:146136371 FBXO30 -0.52 -4.67 -0.39 7.83e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg05665937 chr4:1216051 CTBP1 0.24 4.47 0.37 1.72e-5 Obesity-related traits; TGCT cis rs11858159 0.545 rs6576303 chr15:24641281 G/A cg08449389 chr15:24672285 NA 0.43 4.53 0.38 1.36e-5 Platelet thrombus formation; TGCT cis rs57221529 0.766 rs4081846 chr5:574019 G/A cg09021430 chr5:549028 NA -0.37 -5.29 -0.43 5.46e-7 Lung disease severity in cystic fibrosis; TGCT cis rs79349575 0.783 rs62075838 chr17:46996432 C/T cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs9926296 0.605 rs3743859 chr16:89846050 A/G cg04287289 chr16:89883240 FANCA -0.94 -11.74 -0.73 7.28e-22 Vitiligo; TGCT cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg13695892 chr22:41940480 POLR3H -0.92 -9.08 -0.63 2.06e-15 Vitiligo; TGCT cis rs8064299 0.752 rs4789096 chr17:72772698 G/C cg25054828 chr17:72772726 NAT9;TMEM104 0.95 10.83 0.7 1.22e-19 Monocyte count; TGCT cis rs909674 0.541 rs5750816 chr22:39810379 A/G cg11247378 chr22:39784982 NA 0.73 9.83 0.66 3.27e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg01411255 chr17:61851458 DDX42;CCDC47 1.06 13.37 0.77 8.58e-26 Height; TGCT cis rs7824557 0.583 rs6601585 chr8:11233659 A/G cg21775007 chr8:11205619 TDH -0.66 -6.78 -0.52 4.4e-10 Retinal vascular caliber; TGCT cis rs7000551 0.715 rs12544074 chr8:22338378 A/G cg12081754 chr8:22256438 SLC39A14 0.31 5.06 0.41 1.48e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4906332 1.000 rs2246490 chr14:103984294 G/T cg26031613 chr14:104095156 KLC1 0.6 5.33 0.43 4.56e-7 Coronary artery disease; TGCT cis rs9357506 0.967 rs1372568 chr6:46305454 T/C cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.37e-7 Body mass index; TGCT cis rs2070433 0.706 rs2268524 chr21:47838700 C/T cg12379764 chr21:47803548 PCNT 0.57 4.86 0.4 3.52e-6 Lymphocyte counts; TGCT cis rs9911578 1.000 rs9915935 chr17:56843048 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.791 rs9390336 chr6:145896823 A/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.615 rs583182 chr11:68678634 C/T cg21862992 chr11:68658383 NA 0.46 6.39 0.5 3.1e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9921338 1.000 rs9921338 chr16:11416839 T/C cg00044050 chr16:11439710 C16orf75 0.97 7.45 0.56 1.4e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9911578 0.935 rs2302189 chr17:56584205 A/C cg05425664 chr17:57184151 TRIM37 0.63 6.4 0.5 2.84e-9 Intelligence (multi-trait analysis); TGCT cis rs72781680 0.665 rs2675356 chr2:24074734 C/T cg08917208 chr2:24149416 ATAD2B 0.77 4.74 0.39 5.69e-6 Lymphocyte counts; TGCT cis rs6684514 0.778 rs11264477 chr1:156321154 C/T cg16558208 chr1:156270281 VHLL 0.4 8.41 0.6 8.11e-14 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9796 0.558 rs6492993 chr15:41526104 G/A cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.85 -0.52 3.01e-10 Menopause (age at onset); TGCT cis rs13256369 0.951 rs10503394 chr8:8565775 A/G cg18904891 chr8:8559673 CLDN23 0.6 5.58 0.45 1.47e-7 Obesity-related traits; TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg08736216 chr1:53307985 ZYG11A -0.29 -5.96 -0.47 2.43e-8 Monocyte count; TGCT cis rs17376456 0.741 rs10036829 chr5:93309897 G/C cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs734999 0.545 rs7364820 chr1:2556709 G/A cg18854424 chr1:2615690 NA 0.45 5.15 0.42 1e-6 Ulcerative colitis; TGCT cis rs2153535 0.580 rs6597322 chr6:8449952 T/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs921968 0.510 rs620887 chr2:219465594 C/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7089973 0.584 rs6585300 chr10:116639889 A/C cg03647239 chr10:116582469 FAM160B1 0.59 5.57 0.45 1.51e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs748404 0.631 rs2467745 chr15:43722742 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs6840360 0.571 rs4696270 chr4:152498289 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.774 rs11249893 chr8:8700851 C/T cg15556689 chr8:8085844 FLJ10661 0.72 6.72 0.52 5.75e-10 Mood instability; TGCT cis rs7714584 1.000 rs12054923 chr5:150249059 A/G cg22134413 chr5:150180641 NA 0.87 6.8 0.52 3.87e-10 Crohn's disease; TGCT cis rs910316 0.870 rs7147712 chr14:75670707 C/G cg08847533 chr14:75593920 NEK9 -0.93 -10.86 -0.7 1.02e-19 Height; TGCT cis rs79349575 0.721 rs2291725 chr17:47039132 T/C cg26022315 chr17:47021804 SNF8 0.49 4.77 0.39 5.18e-6 Type 2 diabetes; TGCT cis rs2880765 0.835 rs6497202 chr15:86021375 T/C cg13263323 chr15:86062960 AKAP13 -0.23 -4.9 -0.4 2.91e-6 Coronary artery disease; TGCT cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.56 4.97 0.41 2.19e-6 Height; TGCT cis rs7208859 0.673 rs78799101 chr17:29215160 A/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs2233152 0.519 rs10423139 chr19:41320459 C/G cg23963070 chr1:1162176 SDF4 0.32 6.9 0.53 2.33e-10 Kawasaki disease; TGCT cis rs6539288 0.563 rs11113122 chr12:107211325 T/C cg15890332 chr12:107067104 RFX4 0.23 4.75 0.39 5.45e-6 Total body bone mineral density; TGCT cis rs9653442 0.564 rs7565895 chr2:100774773 G/A cg22139774 chr2:100720529 AFF3 -0.34 -5.4 -0.44 3.21e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6426558 0.537 rs6662583 chr1:227383889 A/G cg10327440 chr1:227177885 CDC42BPA -0.61 -7.32 -0.55 2.72e-11 Neutrophil percentage of white cells; TGCT cis rs7829975 0.560 rs6994131 chr8:8550958 G/A cg17143192 chr8:8559678 CLDN23 -0.49 -4.94 -0.41 2.44e-6 Mood instability; TGCT cis rs4727027 0.866 rs3927307 chr7:148774869 C/T cg23583168 chr7:148888333 NA -0.69 -8.67 -0.61 2.04e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs3020736 0.500 rs6002603 chr22:42492362 C/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.85e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs875971 1.000 rs7792762 chr7:66004138 T/C cg18876405 chr7:65276391 NA 0.32 4.9 0.4 2.99e-6 Aortic root size; TGCT cis rs3087591 0.922 rs2905799 chr17:29536901 G/A cg24425628 chr17:29625626 OMG;NF1 0.48 7.29 0.55 3.25e-11 Hip circumference; TGCT cis rs7267979 1.000 rs3761117 chr20:25388070 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9677476 0.632 rs10198572 chr2:232096723 G/A cg07929768 chr2:232055508 NA 0.33 5.16 0.42 9.37e-7 Food antigen IgG levels; TGCT cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs698813 0.543 rs12468824 chr2:44482448 G/T cg00619915 chr2:44497795 NA -0.24 -5.68 -0.45 9.26e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs9650657 0.737 rs2409669 chr8:10623969 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.44 -0.37 1.97e-5 Neuroticism; TGCT cis rs72781680 0.752 rs72796130 chr2:23919740 T/C cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg17264618 chr3:40429014 ENTPD3 -0.32 -4.45 -0.37 1.9e-5 Renal cell carcinoma; TGCT cis rs12291225 0.585 rs34171876 chr11:14353957 G/C cg19336497 chr11:14380999 RRAS2 -0.44 -7.11 -0.54 8.3e-11 Sense of smell; TGCT cis rs6121246 0.559 rs6119728 chr20:30413121 G/A cg10886678 chr20:30946050 ASXL1 -0.57 -4.79 -0.4 4.68e-6 Mean corpuscular hemoglobin; TGCT cis rs7781977 0.695 rs6583437 chr7:50350267 C/T cg14216940 chr7:50343131 IKZF1 0.36 4.55 0.38 1.25e-5 IgG glycosylation; TGCT cis rs1692580 0.807 rs4648818 chr1:2178999 C/T cg21194808 chr1:2205498 SKI 0.29 5.74 0.46 6.76e-8 Coronary artery disease; TGCT cis rs2228479 0.702 rs17226841 chr16:89828484 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs35849525 1.000 rs35849525 chr3:50067350 T/C cg14019146 chr3:50243930 SLC38A3 -0.21 -4.51 -0.38 1.47e-5 Intelligence (multi-trait analysis); TGCT cis rs950169 0.887 rs3860265 chr15:84945185 C/T cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs12188164 0.965 rs41282625 chr5:475626 C/G cg17553881 chr5:443987 EXOC3;C5orf55 -0.41 -4.76 -0.39 5.28e-6 Cystic fibrosis severity; TGCT cis rs5750830 0.649 rs5757663 chr22:39821319 T/C cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs73036520 0.646 rs11672894 chr19:45801951 A/G cg20198684 chr19:45742032 NA -0.24 -4.46 -0.37 1.78e-5 Monocyte percentage of white cells; TGCT cis rs1372520 0.532 rs2583972 chr4:90747411 T/G cg14346243 chr4:90757452 SNCA -0.64 -5.26 -0.43 6.04e-7 Neuroticism; TGCT cis rs950169 0.526 rs698620 chr15:85177208 G/A cg12501888 chr15:85177176 SCAND2 -0.49 -4.61 -0.38 9.75e-6 Schizophrenia; TGCT cis rs1018836 0.923 rs6989123 chr8:91551234 A/T cg16814680 chr8:91681699 NA -0.88 -9.81 -0.66 3.71e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs8038465 0.592 rs58443257 chr15:73930707 A/T cg15420318 chr15:73925796 NPTN 0.67 6.99 0.53 1.52e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1043515 0.642 rs8592 chr17:36958065 A/G cg09592244 chr17:37024020 NA 0.49 4.86 0.4 3.55e-6 Height; TGCT cis rs6657613 0.903 rs9435659 chr1:17313343 G/A cg21692666 chr1:17199302 NA -0.42 -4.52 -0.38 1.43e-5 Hip circumference adjusted for BMI; TGCT cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs4972806 0.814 rs4246626 chr2:177046430 A/C cg14324370 chr2:177042789 NA 0.72 6.82 0.52 3.54e-10 IgG glycosylation; TGCT cis rs2153535 0.580 rs1335641 chr6:8487860 G/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1035144 0.505 rs10145099 chr14:81456694 C/T cg06600135 chr14:81408086 NA -0.48 -4.49 -0.37 1.58e-5 Male sexual orientation; TGCT cis rs7937682 0.889 rs558736 chr11:111500760 C/G cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.12e-21 Primary sclerosing cholangitis; TGCT cis rs7572733 0.534 rs700681 chr2:198711502 C/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT trans rs4332037 0.624 rs73046339 chr7:1889300 G/A cg10840412 chr1:235813424 GNG4 0.85 6.68 0.51 7.16e-10 Bipolar disorder; TGCT cis rs2439831 0.850 rs12440573 chr15:44108997 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.27 0.49 5.48e-9 Lung cancer in ever smokers; TGCT cis rs137699 1.000 rs760742 chr22:39755190 G/T cg24399712 chr22:39784796 NA -0.63 -5.63 -0.45 1.16e-7 IgG glycosylation; TGCT cis rs36051895 0.632 rs12352022 chr9:5161836 T/G cg02405213 chr9:5042618 JAK2 -0.71 -9.01 -0.63 3.02e-15 Pediatric autoimmune diseases; TGCT cis rs9644630 0.504 rs62496181 chr8:19318989 A/T cg06699216 chr8:19333253 CSGALNACT1 -0.25 -4.44 -0.37 1.95e-5 Oropharynx cancer; TGCT cis rs1568889 0.877 rs57202579 chr11:28221677 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.8 7.68 0.57 4.16e-12 Bipolar disorder; TGCT cis rs875971 0.862 rs10278014 chr7:66051264 C/T cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs2836974 0.653 rs8130556 chr21:40516872 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.36 0.64 4.55e-16 Cognitive function; TGCT cis rs7666738 0.830 rs1527517 chr4:98931907 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs5769765 1.000 rs5770742 chr22:50270309 T/C cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT trans rs2243480 1.000 rs2707831 chr7:66062511 G/A cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs17376456 0.877 rs12716460 chr5:93416733 A/G cg25358565 chr5:93447407 FAM172A 0.93 8.45 0.6 6.7e-14 Diabetic retinopathy; TGCT cis rs6089829 0.925 rs3746748 chr20:61667526 C/T cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9468199 0.510 rs72845064 chr6:27654970 C/A cg08851530 chr6:28072375 NA 1.56 7.38 0.55 1.95e-11 Parkinson's disease; TGCT cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs9291683 0.546 rs6829727 chr4:10051672 A/C cg11266682 chr4:10021025 SLC2A9 0.61 7.77 0.57 2.57e-12 Bone mineral density; TGCT cis rs9394841 0.692 rs35085306 chr6:41856002 A/G cg08135965 chr6:41755394 TOMM6 0.56 4.99 0.41 1.98e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs8026198 0.705 rs4583208 chr15:42556757 A/C cg23803468 chr15:43513504 EPB42 -0.36 -4.76 -0.39 5.38e-6 Fibrinogen levels; TGCT trans rs4332037 0.906 rs6461009 chr7:1952139 T/C cg10840412 chr1:235813424 GNG4 -1.06 -8.36 -0.6 1.05e-13 Bipolar disorder; TGCT cis rs610932 0.517 rs620612 chr11:59991847 C/T cg18570331 chr11:60101691 MS4A6E 0.5 4.55 0.38 1.28e-5 Alzheimer's disease; TGCT cis rs7954584 0.504 rs10840633 chr12:122377511 A/T cg22168489 chr12:122356033 WDR66 0.22 4.78 0.39 4.94e-6 Mean corpuscular volume; TGCT cis rs2013441 1.000 rs2526458 chr17:20092200 C/T cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs4665809 0.938 rs4665822 chr2:26312555 C/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs9399135 0.967 rs6908512 chr6:135367757 A/G cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs17718580 1.000 rs17718580 chr14:50973632 A/G cg04730355 chr14:51134070 SAV1 -0.92 -5.17 -0.42 9e-7 Cognitive performance; TGCT cis rs5769765 0.874 rs11703411 chr22:50258751 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.08 11.31 0.71 8.31e-21 Schizophrenia; TGCT cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg05665937 chr4:1216051 CTBP1 0.24 4.63 0.38 8.9e-6 Obesity-related traits; TGCT cis rs1867631 1.000 rs10889636 chr1:67089924 A/G cg13052034 chr1:66999238 SGIP1 -0.55 -4.75 -0.39 5.5e-6 Menopause (age at onset); TGCT cis rs769267 0.930 rs10414830 chr19:19562332 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.65 5.4 0.44 3.25e-7 Tonsillectomy; TGCT cis rs7726839 0.718 rs6887972 chr5:597274 C/G cg09021430 chr5:549028 NA -0.41 -5.83 -0.46 4.48e-8 Obesity-related traits; TGCT cis rs7208859 0.623 rs9899692 chr17:29156939 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4819052 0.679 rs28623526 chr21:46712324 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.65 6.34 0.49 3.83e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs769267 0.930 rs10419912 chr19:19597055 A/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.68 -5.73 -0.46 7.3e-8 Tonsillectomy; TGCT cis rs2439831 1.000 rs690436 chr15:43761205 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs950169 0.840 rs35522895 chr15:84928049 G/A cg12863693 chr15:85201151 NMB 0.41 4.47 0.37 1.75e-5 Schizophrenia; TGCT cis rs79839061 0.636 rs73207778 chr4:836762 C/T cg07828340 chr4:882639 GAK 0.36 4.79 0.4 4.71e-6 Intelligence (multi-trait analysis); TGCT cis rs7635838 0.892 rs9874535 chr3:11463730 A/G cg00170343 chr3:11313890 ATG7 0.65 6.17 0.48 8.85e-9 HDL cholesterol; TGCT cis rs12289510 0.539 rs3808995 chr11:124955977 A/G cg03868193 chr11:124958746 SLC37A2 0.43 6.04 0.48 1.63e-8 Platelet-derived growth factor BB levels; TGCT cis rs9653442 0.564 rs56054309 chr2:100794940 T/C cg07810366 chr2:100720526 AFF3 -0.34 -5.15 -0.42 9.98e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs546131 0.928 rs535719 chr11:34853382 A/G cg11058730 chr11:34937778 PDHX;APIP 0.57 5.12 0.42 1.12e-6 Lung disease severity in cystic fibrosis; TGCT cis rs2692947 0.644 rs1168974 chr2:96814928 G/A cg22654517 chr2:96458247 NA 0.23 4.86 0.4 3.42e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4253772 0.530 rs9615958 chr22:46751122 A/G cg24881330 chr22:46731750 TRMU 1.06 5.5 0.44 2.08e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs4319547 0.876 rs10846978 chr12:122964708 T/C cg23029597 chr12:123009494 RSRC2 -0.29 -4.87 -0.4 3.34e-6 Body mass index; TGCT cis rs950776 0.714 rs615470 chr15:78885988 T/C cg06917634 chr15:78832804 PSMA4 -0.65 -5.29 -0.43 5.4e-7 Sudden cardiac arrest; TGCT cis rs208520 0.955 rs12202599 chr6:67001573 A/G cg07460842 chr6:66804631 NA 0.69 5.83 0.46 4.48e-8 Exhaled nitric oxide output; TGCT cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.94 -0.53 1.89e-10 Alzheimer's disease; TGCT cis rs682748 0.870 rs4643956 chr5:17123497 C/G cg23987134 chr5:17158319 LOC285696 -0.21 -4.98 -0.41 2.05e-6 Hippocampal atrophy; TGCT cis rs2439831 1.000 rs2245790 chr15:43744457 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs523522 0.962 rs4767914 chr12:120993817 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs17490626 0.568 rs12416520 chr10:71211945 A/G cg12610070 chr10:71211762 TSPAN15 -0.62 -7.23 -0.54 4.32e-11 Thrombosis; TGCT cis rs7017914 0.905 rs3110241 chr8:71932964 C/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs2153535 0.541 rs6932434 chr6:8467679 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs3087591 0.810 rs2269856 chr17:29482701 C/T cg24425628 chr17:29625626 OMG;NF1 0.43 6.31 0.49 4.5e-9 Hip circumference; TGCT cis rs2688608 0.620 rs7076525 chr10:75512797 C/T cg19442545 chr10:75533431 FUT11 -0.36 -5.74 -0.46 6.99e-8 Inflammatory bowel disease; TGCT cis rs72781680 0.821 rs72796361 chr2:24160689 A/T cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs1055129 0.560 rs3682 chr17:73942150 A/G cg08125733 chr17:73851984 WBP2 0.57 5.37 0.43 3.73e-7 White matter hyperintensity burden; TGCT cis rs72781680 0.898 rs72798041 chr2:23953076 T/C cg08917208 chr2:24149416 ATAD2B 0.95 5.99 0.47 2.12e-8 Lymphocyte counts; TGCT cis rs16866061 1.000 rs7588380 chr2:225341304 A/T cg12698349 chr2:225449008 CUL3 -0.96 -9.45 -0.65 2.69e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs10782582 0.586 rs11161902 chr1:76392498 C/G cg10523679 chr1:76189770 ACADM -0.54 -4.89 -0.4 3.03e-6 Daytime sleep phenotypes; TGCT cis rs17376456 0.569 rs2045020 chr5:93224466 T/C cg25358565 chr5:93447407 FAM172A -0.81 -6.5 -0.5 1.79e-9 Diabetic retinopathy; TGCT cis rs9325144 0.510 rs7952795 chr12:38720686 C/T cg26384229 chr12:38710491 ALG10B 0.64 6.0 0.47 2.03e-8 Morning vs. evening chronotype; TGCT cis rs35146811 0.807 rs10228764 chr7:99608029 A/G cg13334819 chr7:99746414 C7orf59 -0.82 -7.38 -0.55 2.05e-11 Coronary artery disease; TGCT cis rs910187 0.532 rs6066209 chr20:45762795 G/T cg27589058 chr20:45804311 EYA2 -0.33 -6.08 -0.48 1.35e-8 Migraine; TGCT cis rs2455799 0.613 rs2246960 chr3:15717693 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.65e-6 Mean platelet volume; TGCT cis rs523522 1.000 rs523522 chr12:121020250 A/T cg27279351 chr12:120934652 DYNLL1 0.68 5.74 0.46 6.83e-8 High light scatter reticulocyte count; TGCT cis rs34014631 0.681 rs115614611 chr10:103745041 G/A cg22630918 chr10:102748988 C10orf2 0.4 4.44 0.37 1.93e-5 Coronary artery calcification; TGCT cis rs763121 0.889 rs6001209 chr22:39121252 C/T cg06022373 chr22:39101656 GTPBP1 -0.61 -5.09 -0.42 1.28e-6 Menopause (age at onset); TGCT cis rs7590720 0.819 rs6435931 chr2:216892754 C/G cg12620499 chr2:216877984 MREG 0.9 9.89 0.66 2.3e-17 Alcohol dependence; TGCT cis rs939574 0.790 rs72955444 chr2:220094673 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.11 5.34 0.43 4.31e-7 Platelet distribution width; TGCT cis rs7769051 1.000 rs6934161 chr6:133124077 C/T cg22852734 chr6:133119734 C6orf192 -1.23 -7.35 -0.55 2.28e-11 Type 2 diabetes nephropathy; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg22166914 chr1:53195759 ZYG11B -0.37 -6.35 -0.5 3.7e-9 Monocyte count; TGCT cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT trans rs4820792 0.945 rs2017309 chr22:29131426 A/T cg16744250 chr20:62209504 NA 0.29 6.9 0.53 2.41e-10 Breast size; TGCT cis rs2070488 0.931 rs7630012 chr3:38552250 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.86 -8.57 -0.61 3.38e-14 Electrocardiographic conduction measures; TGCT cis rs10197940 0.662 rs72860233 chr2:152289767 G/A cg19508488 chr2:152266495 RIF1 0.72 6.56 0.51 1.31e-9 Lung cancer; TGCT cis rs7552404 0.696 rs67487205 chr1:76373756 T/C cg10523679 chr1:76189770 ACADM 0.84 7.32 0.55 2.77e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg00024416 chr22:24240387 NA 0.25 4.85 0.4 3.64e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs12986207 0.887 rs7251052 chr19:29897537 A/G cg09614724 chr19:30719547 NA -0.64 -4.5 -0.37 1.53e-5 Bulimia nervosa; TGCT cis rs9733 0.596 rs56058687 chr1:150635066 C/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.85 0.4 3.65e-6 Tonsillectomy; TGCT cis rs6598955 0.543 rs61608823 chr1:26555090 G/A cg04990556 chr1:26633338 UBXN11 0.8 7.3 0.55 3.01e-11 Obesity-related traits; TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg23850913 chr6:15505452 JARID2 0.97 5.56 0.45 1.55e-7 Gambling; TGCT cis rs174479 0.647 rs174457 chr11:61656975 T/C cg01500311 chr11:61656094 FADS3 0.29 5.08 0.42 1.34e-6 Sphingolipid levels; TGCT cis rs9653442 0.675 rs1115910 chr2:100647872 A/G cg22139774 chr2:100720529 AFF3 -0.41 -7.3 -0.55 3e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9926296 0.682 rs258328 chr16:89730314 C/T cg03388025 chr16:89894329 SPIRE2 -0.36 -5.33 -0.43 4.49e-7 Vitiligo; TGCT cis rs2180341 1.000 rs6903878 chr6:127638600 C/G cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs7086627 0.515 rs10887896 chr10:82210144 A/C cg00277334 chr10:82204260 NA -0.54 -8.46 -0.6 6.41e-14 Post bronchodilator FEV1; TGCT cis rs17401966 0.540 rs11121566 chr1:10472848 C/G cg19773385 chr1:10388646 KIF1B -0.23 -5.46 -0.44 2.52e-7 Hepatocellular carcinoma; TGCT cis rs17270561 0.723 rs12213243 chr6:25890108 C/T cg17691542 chr6:26056736 HIST1H1C 0.88 6.05 0.48 1.56e-8 Iron status biomarkers; TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg18765753 chr7:1198926 ZFAND2A -0.56 -7.1 -0.54 8.67e-11 Longevity;Endometriosis; TGCT cis rs875971 0.862 rs12698521 chr7:65939489 T/C cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs208520 0.802 rs208496 chr6:66930786 G/C cg07460842 chr6:66804631 NA -0.9 -9.16 -0.64 1.34e-15 Exhaled nitric oxide output; TGCT cis rs2228479 0.850 rs62056091 chr16:89930414 G/A cg06558623 chr16:89946397 TCF25 0.55 4.83 0.4 3.89e-6 Skin colour saturation; TGCT cis rs6138458 1.000 rs6707 chr20:24944166 C/T cg26195577 chr20:24973756 C20orf3 1.18 11.12 0.71 2.37e-20 Blood protein levels; TGCT cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg26531700 chr6:26746687 NA 0.68 6.28 0.49 5.15e-9 Intelligence (multi-trait analysis); TGCT cis rs6688613 1.000 rs6427049 chr1:166956593 C/T cg07049167 chr1:166818506 POGK 0.21 4.52 0.38 1.43e-5 Refractive astigmatism; TGCT cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg11062466 chr8:58055876 NA 0.43 4.64 0.38 8.85e-6 Developmental language disorder (linguistic errors); TGCT cis rs910187 0.631 rs2228 chr20:45809941 G/A cg27589058 chr20:45804311 EYA2 -0.38 -8.34 -0.6 1.18e-13 Migraine; TGCT cis rs12541335 0.639 rs4871994 chr8:22206038 G/A cg26039829 chr8:22132926 PIWIL2 0.27 5.12 0.42 1.16e-6 Hypertriglyceridemia; TGCT cis rs6424115 0.830 rs3003333 chr1:24194014 A/T cg15997130 chr1:24165203 NA -0.9 -10.58 -0.69 4.95e-19 Immature fraction of reticulocytes; TGCT cis rs8177253 0.930 rs12595 chr3:133496553 T/C cg08439880 chr3:133502540 NA -0.31 -5.96 -0.47 2.43e-8 Iron status biomarkers; TGCT cis rs1878931 0.582 rs9937267 chr16:3421073 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 6.35 0.5 3.66e-9 Body mass index (adult); TGCT cis rs7565124 0.954 rs7568484 chr2:20255251 A/G cg00462460 chr2:20212509 MATN3 -0.45 -4.84 -0.4 3.73e-6 Major depressive disorder; TGCT cis rs11874712 0.965 rs11661945 chr18:43672194 T/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.04e-7 Migraine - clinic-based; TGCT cis rs826838 0.934 rs10875647 chr12:38856995 G/A cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs7666738 0.830 rs6833312 chr4:98951356 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7098414 0.511 rs12262228 chr10:82160425 C/T cg01528321 chr10:82214614 TSPAN14 0.56 4.98 0.41 2.07e-6 Post bronchodilator FEV1; TGCT cis rs9341808 0.667 rs10943698 chr6:80934301 C/T cg08355045 chr6:80787529 NA 0.3 4.94 0.41 2.47e-6 Sitting height ratio; TGCT cis rs4680 0.737 rs3810595 chr22:19949644 G/C cg23601416 chr22:19950040 COMT -0.39 -5.07 -0.41 1.44e-6 Blood metabolite levels; TGCT cis rs7666738 0.830 rs58367603 chr4:99015350 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6964587 1.000 rs6956596 chr7:91750107 T/G cg17063962 chr7:91808500 NA 0.88 9.3 0.64 6.22e-16 Breast cancer; TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg08736216 chr1:53307985 ZYG11A -0.28 -5.53 -0.44 1.83e-7 Monocyte count; TGCT cis rs1005277 0.602 rs1831315 chr10:38473353 T/C cg25427524 chr10:38739819 LOC399744 -0.4 -8.5 -0.61 5.12e-14 Extrinsic epigenetic age acceleration; TGCT cis rs3902035 0.964 rs17349133 chr6:118998633 C/T cg07617317 chr6:118971624 C6orf204 0.48 5.52 0.44 1.87e-7 QT interval; TGCT cis rs7772486 0.686 rs1045820 chr6:145947080 C/T cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs3772130 0.961 rs11716984 chr3:121362407 A/T cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.95 0.41 2.41e-6 Cognitive performance; TGCT cis rs739496 0.579 rs2879603 chr12:112278025 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs6570726 0.818 rs412350 chr6:145852409 T/C cg05347473 chr6:146136440 FBXO30 0.53 5.02 0.41 1.78e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs34779708 0.931 rs55724039 chr10:35465397 A/G cg03585969 chr10:35415529 CREM 0.43 4.52 0.38 1.4e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs11190604 1.000 rs7070776 chr10:102264672 A/G cg16342193 chr10:102329863 NA -0.39 -5.01 -0.41 1.83e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9902453 0.808 rs76039587 chr17:28233760 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.28 0.55 3.32e-11 Coffee consumption (cups per day); TGCT cis rs1008375 0.931 rs6449309 chr4:17573208 C/T cg18681998 chr4:17616180 MED28 0.84 8.03 0.58 6.49e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4478858 0.684 rs3753374 chr1:31740668 C/T cg07478791 chr1:31886160 SERINC2 -0.48 -4.6 -0.38 1.05e-5 Alcohol dependence; TGCT cis rs909341 0.909 rs1741708 chr20:62372041 G/T cg14758556 chr20:62440591 NA 0.3 4.53 0.38 1.38e-5 Atopic dermatitis; TGCT cis rs9914544 1.000 rs28436199 chr17:18751730 C/T cg26378065 chr17:18585709 ZNF286B 0.54 4.88 0.4 3.19e-6 Educational attainment (years of education); TGCT cis rs7949030 0.695 rs11231161 chr11:62378221 A/G cg22862634 chr11:62369728 EML3;MTA2 0.69 8.84 0.62 7.84e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT trans rs7618501 0.633 rs2526748 chr3:50080439 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs9837602 0.529 rs1087198 chr3:99524381 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.71 0.52 6.1e-10 Breast cancer; TGCT cis rs2019216 0.542 rs1850564 chr17:21911794 T/C cg22648282 chr17:21454238 C17orf51 -0.59 -5.8 -0.46 5.18e-8 Pelvic organ prolapse; TGCT cis rs13217239 0.646 rs10946891 chr6:26973215 T/C cg26531700 chr6:26746687 NA 0.68 6.79 0.52 4.1e-10 Schizophrenia; TGCT cis rs1799949 0.965 rs9646413 chr17:41426157 A/G cg10047753 chr17:41438598 NA 0.72 7.0 0.53 1.39e-10 Menopause (age at onset); TGCT cis rs4851266 0.966 rs2309838 chr2:100838455 T/C cg22139774 chr2:100720529 AFF3 -0.34 -5.09 -0.42 1.28e-6 Educational attainment; TGCT cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg11644478 chr21:40555479 PSMG1 1.03 10.99 0.7 4.96e-20 Cognitive function; TGCT cis rs7100689 0.754 rs10736339 chr10:82059970 G/C cg01528321 chr10:82214614 TSPAN14 0.8 7.9 0.58 1.29e-12 Post bronchodilator FEV1; TGCT cis rs727563 0.593 rs132770 chr22:42017264 A/G cg03806693 chr22:41940476 POLR3H 1.06 11.15 0.71 1.99e-20 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10479542 0.929 rs10074573 chr5:178976966 C/T cg19723775 chr5:179050963 HNRNPH1 -0.52 -5.25 -0.43 6.46e-7 Lung cancer; TGCT cis rs6087990 0.735 rs2424914 chr20:31374520 A/G cg13636640 chr20:31349939 DNMT3B 0.95 12.38 0.74 2.0500000000000001e-23 Ulcerative colitis; TGCT cis rs1008375 0.932 rs2302391 chr4:17660237 T/C cg18681998 chr4:17616180 MED28 1.03 11.57 0.72 1.95e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1552244 0.882 rs6443279 chr3:10053599 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.43 -0.5 2.53e-9 Alzheimer's disease; TGCT cis rs7582180 0.629 rs11686649 chr2:100946701 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.781 rs2207146 chr6:88180641 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.54 -5.23 -0.43 7.03e-7 Monocyte percentage of white cells; TGCT trans rs1814175 0.817 rs1996982 chr11:49972619 G/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs7666738 0.830 rs62321597 chr4:99014221 C/A cg05340658 chr4:99064831 C4orf37 0.47 5.33 0.43 4.51e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.704 rs11884395 chr2:238359366 C/T cg14458575 chr2:238380390 NA 0.56 8.36 0.6 1.06e-13 Prostate cancer; TGCT cis rs2730245 0.527 rs2527205 chr7:158706393 G/T cg11984989 chr7:158649758 WDR60 -1.01 -7.85 -0.58 1.65e-12 Height; TGCT cis rs10067451 0.711 rs116552258 chr5:87857702 C/T cg24804195 chr5:87968844 LOC645323 0.91 4.77 0.39 5.04e-6 Photic sneeze reflex; TGCT cis rs7542091 0.704 rs7537294 chr1:210043777 A/G cg21951975 chr1:209979733 IRF6 0.6 6.1 0.48 1.24e-8 Monobrow; TGCT cis rs597539 0.690 rs552517 chr11:68625286 T/G cg04772025 chr11:68637568 NA 0.61 6.53 0.51 1.51e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs4650994 1.000 rs10913572 chr1:178526718 C/T cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.54e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6754311 0.509 rs3820794 chr2:136505546 C/T cg07169764 chr2:136633963 MCM6 -0.71 -6.47 -0.5 2.09e-9 Mosquito bite size; TGCT cis rs1691799 0.899 rs1185244 chr12:66725160 C/T cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.77e-9 White blood cell count (basophil); TGCT cis rs12620999 0.941 rs4663701 chr2:238036884 C/T cg23555395 chr2:238036564 NA -0.3 -5.21 -0.42 7.5e-7 Systemic lupus erythematosus; TGCT cis rs425277 1.000 rs436045 chr1:2071556 A/G cg24578937 chr1:2090814 PRKCZ -0.31 -7.57 -0.56 7.52e-12 Height; TGCT cis rs3808502 0.647 rs7821302 chr8:11236572 T/A cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Neuroticism; TGCT cis rs977747 0.872 rs4926524 chr1:47679258 C/T cg03885399 chr1:47691550 TAL1 -0.4 -5.15 -0.42 1e-6 Body mass index; TGCT cis rs4478858 0.735 rs34960310 chr1:31816197 A/G cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs4911259 0.593 rs6058924 chr20:31464467 G/A cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs17030434 0.863 rs17030382 chr4:154650887 A/G cg14289246 chr4:154710475 SFRP2 -0.88 -6.97 -0.53 1.62e-10 Electrocardiographic conduction measures; TGCT cis rs739496 0.947 rs3803170 chr12:111847740 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.32 0.43 4.6e-7 Platelet count; TGCT cis rs9300255 0.698 rs4759416 chr12:123746357 C/G cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg08627397 chr16:89984028 MC1R 0.32 5.19 0.42 8.18e-7 Vitiligo; TGCT cis rs6558174 0.965 rs4072394 chr8:22490800 C/T cg03733263 chr8:22462867 KIAA1967 0.67 5.35 0.43 4.11e-7 Breast cancer; TGCT cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs4499344 0.730 rs7247597 chr19:33102257 C/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.63 0.61 2.53e-14 Mean platelet volume; TGCT cis rs6988636 1.000 rs28670850 chr8:124189125 A/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs66573146 1.000 rs66573146 chr4:6984464 C/G cg05069807 chr4:6945702 TBC1D14 0.35 4.94 0.41 2.51e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs10089 0.953 rs4836358 chr5:127376869 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs6565180 0.962 rs6565182 chr16:30374381 C/T cg17640201 chr16:30407289 ZNF48 -0.87 -8.21 -0.59 2.4e-13 Tonsillectomy; TGCT cis rs7043114 0.525 rs7869742 chr9:95256174 A/G cg14311495 chr9:95764742 FGD3 -0.22 -4.49 -0.37 1.6e-5 Height; TGCT cis rs9902453 0.899 rs8067580 chr17:28471248 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs1801251 1.000 rs12987513 chr2:233622066 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.45 0.5 2.22e-9 Coronary artery disease; TGCT cis rs526231 0.819 rs26232 chr5:102596720 C/T cg05225461 chr5:102596755 C5orf30 0.22 4.49 0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs9486719 1.000 rs2263192 chr6:96873037 C/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs8177253 0.898 rs8177258 chr3:133480387 C/A cg16414030 chr3:133502952 NA -0.61 -9.66 -0.66 8.36e-17 Iron status biomarkers; TGCT cis rs4499344 0.633 rs259260 chr19:33153261 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs250677 0.652 rs1422582 chr5:148436925 T/C cg18129178 chr5:148520854 ABLIM3 -0.42 -5.74 -0.46 6.77e-8 Breast cancer; TGCT cis rs12257961 0.549 rs1949435 chr10:15373670 G/T cg10616319 chr10:15468812 NA -0.25 -4.51 -0.38 1.46e-5 Selective IgA deficiency; TGCT cis rs3806843 0.966 rs2563264 chr5:140137503 T/G cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4689388 0.926 rs3889821 chr4:6282596 C/T cg00701064 chr4:6280414 WFS1 0.45 6.19 0.49 8e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2239547 0.607 rs9836178 chr3:52925403 T/C cg11645453 chr3:52864694 ITIH4 -0.36 -5.76 -0.46 6.15e-8 Schizophrenia; TGCT cis rs6448317 0.911 rs10939013 chr4:24903015 G/A cg21108841 chr4:24914750 CCDC149 0.68 5.58 0.45 1.43e-7 Heschl's gyrus morphology; TGCT cis rs56804039 0.524 rs6982112 chr8:8372376 C/G cg14215082 chr8:9055850 NA -0.46 -4.47 -0.37 1.71e-5 Cervical cancer; TGCT cis rs11148252 0.904 rs9526927 chr13:53051627 C/T cg00495681 chr13:53174319 NA 0.61 6.42 0.5 2.61e-9 Lewy body disease; TGCT cis rs1008375 1.000 rs2159583 chr4:17658838 T/C cg10189774 chr4:17578691 LAP3 0.57 5.13 0.42 1.07e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg27286337 chr10:134555280 INPP5A 0.42 5.22 0.42 7.35e-7 Migraine; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg10108389 chr3:44770937 ZNF501 -0.48 -4.82 -0.4 4.2e-6 Depressive symptoms; TGCT cis rs10089 1.000 rs77086350 chr5:127494431 G/A cg19767477 chr5:127420684 SLC12A2 -0.43 -4.61 -0.38 9.87e-6 Ileal carcinoids; TGCT cis rs12368653 0.693 rs2640610 chr12:58037435 T/A cg12615879 chr12:58013172 SLC26A10 0.44 5.06 0.41 1.48e-6 Multiple sclerosis; TGCT cis rs9902453 1.000 rs11080114 chr17:28407287 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -6.77 -0.52 4.55e-10 Coffee consumption (cups per day); TGCT cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg02073558 chr3:44770973 ZNF501 0.57 5.5 0.44 2.05e-7 Depressive symptoms; TGCT cis rs9913156 0.517 rs2326118 chr17:4611851 C/T cg00122941 chr17:4613640 ARRB2 0.79 7.1 0.54 8.67e-11 Lymphocyte counts; TGCT cis rs9346649 0.630 rs4708643 chr6:168491681 A/G cg02770688 chr6:168491649 NA 0.34 6.05 0.48 1.6e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs7959452 0.590 rs28778648 chr12:69771911 C/A cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs3780378 1.000 rs1328918 chr9:5107394 A/G cg03508284 chr9:4985524 JAK2 -0.5 -4.57 -0.38 1.16e-5 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9682041 0.622 rs7640791 chr3:170155726 G/C cg11886554 chr3:170076028 SKIL 0.83 6.08 0.48 1.38e-8 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7714584 1.000 rs11167521 chr5:150271785 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs2180341 0.814 rs6914131 chr6:127737489 T/C cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs3751972 0.590 rs35106758 chr17:26263783 C/A cg02948944 chr17:26242737 NA -0.46 -5.71 -0.46 7.8e-8 Fractional exhaled nitric oxide (childhood); TGCT cis rs240764 0.618 rs846778 chr6:101273147 T/C cg21058520 chr6:100914733 NA -0.36 -4.58 -0.38 1.12e-5 Neuroticism; TGCT cis rs763121 0.853 rs1569492 chr22:38975511 A/G cg06022373 chr22:39101656 GTPBP1 -0.72 -7.02 -0.53 1.28e-10 Menopause (age at onset); TGCT cis rs2242116 0.727 rs7635480 chr3:46968227 T/C cg27129171 chr3:47204927 SETD2 0.66 6.67 0.51 7.46e-10 Birth weight; TGCT cis rs10504229 0.636 rs115738451 chr8:58055133 A/T cg20607798 chr8:58055168 NA 0.62 5.19 0.42 8.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs6964587 0.677 rs62467839 chr7:91967371 A/G cg17063962 chr7:91808500 NA 0.81 7.78 0.57 2.45e-12 Breast cancer; TGCT cis rs3862435 0.572 rs2601164 chr15:90908402 A/G cg14166756 chr15:90894880 ZNF774 0.31 4.99 0.41 2e-6 Response to exercise (triglyceride level interaction); TGCT cis rs7927771 0.826 rs2293578 chr11:47437403 C/T cg10139015 chr11:47448256 PSMC3 0.52 4.46 0.37 1.78e-5 Subjective well-being; TGCT cis rs116095464 0.510 rs7714944 chr5:231765 C/T cg22857025 chr5:266934 NA -0.33 -6.49 -0.5 1.84e-9 Breast cancer; TGCT cis rs17102423 0.723 rs8181938 chr14:65555712 A/G cg11161011 chr14:65562177 MAX -0.55 -7.67 -0.57 4.42e-12 Obesity-related traits; TGCT cis rs6940638 0.688 rs9379960 chr6:27121325 A/C cg26531700 chr6:26746687 NA -0.54 -4.84 -0.4 3.8e-6 Intelligence (multi-trait analysis); TGCT cis rs854765 0.682 rs13306736 chr17:17740281 C/T cg09796270 chr17:17721594 SREBF1 -0.25 -4.93 -0.4 2.63e-6 Total body bone mineral density; TGCT cis rs9894429 0.716 rs7405578 chr17:79588306 C/A cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.22e-10 Eye color traits; TGCT cis rs4253772 0.591 rs6008538 chr22:46685963 G/A cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 5.27 0.43 5.83e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs12681287 0.547 rs56752411 chr8:87515156 C/T cg19078186 chr8:87526527 CPNE3 -0.36 -4.49 -0.37 1.59e-5 Caudate activity during reward; TGCT cis rs3749237 0.595 rs1464567 chr3:49459252 C/G cg02487422 chr3:49467188 NICN1 -0.63 -6.55 -0.51 1.37e-9 Resting heart rate; TGCT cis rs1059312 0.932 rs11059916 chr12:129287609 C/A cg09035930 chr12:129282057 SLC15A4 0.58 11.18 0.71 1.67e-20 Systemic lupus erythematosus; TGCT cis rs6964587 1.000 rs6968870 chr7:91661111 G/C cg22709100 chr7:91322751 NA 0.28 4.58 0.38 1.11e-5 Breast cancer; TGCT cis rs617219 0.684 rs2896766 chr5:78586493 A/G cg23514016 chr5:78407564 BHMT -0.32 -4.86 -0.4 3.43e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs986417 0.901 rs10150982 chr14:60987006 T/G cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs6558530 0.730 rs10100341 chr8:1723749 A/G cg09410841 chr8:1729607 CLN8 0.84 9.86 0.66 2.81e-17 Systolic blood pressure; TGCT cis rs10832169 0.901 rs2697820 chr11:14077042 A/T cg04547675 chr11:13986162 SPON1 0.52 4.72 0.39 6.15e-6 Blood protein levels; TGCT cis rs3776081 0.600 rs56757464 chr5:149530423 G/T cg18424208 chr5:149546337 CDX1 -0.25 -4.6 -0.38 1.01e-5 Blood protein levels; TGCT cis rs1511802 0.666 rs4862662 chr4:187118662 A/C cg19358738 chr4:186734530 SORBS2 -0.18 -4.57 -0.38 1.18e-5 Blood protein levels; TGCT cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg11890956 chr21:40555474 PSMG1 1.11 12.17 0.74 6.69e-23 Cognitive function; TGCT cis rs250677 1.000 rs28173 chr5:148423573 C/T cg23229984 chr5:148520753 ABLIM3 0.21 5.08 0.41 1.37e-6 Breast cancer; TGCT trans rs62103177 0.535 rs62101568 chr18:77934671 G/A cg05926928 chr17:57297772 GDPD1 0.8 6.76 0.52 4.84e-10 Opioid sensitivity; TGCT cis rs10876993 0.855 rs10877007 chr12:58100058 T/A cg15848620 chr12:58087721 OS9 -0.72 -5.98 -0.47 2.25e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7923609 0.783 rs7907451 chr10:65328740 T/A cg08743896 chr10:65200160 JMJD1C 0.32 4.46 0.37 1.82e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs17376456 0.825 rs13357713 chr5:93145423 T/C cg25358565 chr5:93447407 FAM172A 0.9 7.6 0.56 6.43e-12 Diabetic retinopathy; TGCT cis rs6967414 0.681 rs11979878 chr7:6753803 A/G cg00387323 chr7:6746715 ZNF12 0.77 4.73 0.39 6.05e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg02353165 chr6:42928485 GNMT -0.62 -5.75 -0.46 6.46e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg06873352 chr17:61820015 STRADA 0.54 5.98 0.47 2.24e-8 Prudent dietary pattern; TGCT cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg26566898 chr11:117069891 TAGLN 0.35 4.93 0.41 2.55e-6 Blood protein levels; TGCT cis rs7666738 0.830 rs7689495 chr4:98920152 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.51 0.56 1e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs7767926 chr6:8453557 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs1670533 0.932 rs13106586 chr4:1054182 G/A cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg02018176 chr4:1364513 KIAA1530 0.29 4.81 0.4 4.22e-6 Longevity; TGCT cis rs2230307 0.536 rs12733952 chr1:100611571 A/G cg24955406 chr1:100503596 HIAT1 0.72 4.84 0.4 3.84e-6 Carotid intima media thickness; TGCT cis rs7826238 0.517 rs35144760 chr8:8361723 A/G cg06636001 chr8:8085503 FLJ10661 -0.62 -5.45 -0.44 2.62e-7 Systolic blood pressure; TGCT cis rs9325144 0.555 rs4882359 chr12:38726679 T/C cg13010199 chr12:38710504 ALG10B 0.52 4.54 0.38 1.32e-5 Morning vs. evening chronotype; TGCT cis rs2295359 0.892 rs11209005 chr1:67618678 A/G cg03340356 chr1:67600835 NA 0.39 4.67 0.39 7.71e-6 Psoriasis; TGCT cis rs6840360 0.533 rs4696295 chr4:152717430 T/C cg17479576 chr4:152424074 FAM160A1 0.49 4.84 0.4 3.8e-6 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg18765753 chr7:1198926 ZFAND2A -0.55 -6.86 -0.52 2.84e-10 Longevity;Endometriosis; TGCT cis rs4665809 1.000 rs6704930 chr2:26325705 G/A cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs11249608 0.548 rs2047354 chr5:178455247 T/C cg01312482 chr5:178451176 ZNF879 -0.49 -4.76 -0.39 5.2e-6 Pubertal anthropometrics; TGCT cis rs589249 0.963 rs592799 chr1:37156547 A/G cg04012535 chr1:37176647 NA -0.3 -4.93 -0.4 2.58e-6 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs7674212 0.531 rs4698875 chr4:103933368 T/C cg16532752 chr4:104119610 CENPE -0.56 -5.0 -0.41 1.88e-6 Type 2 diabetes; TGCT cis rs9341808 0.667 rs2505944 chr6:80888410 T/C cg08355045 chr6:80787529 NA 0.3 5.09 0.42 1.27e-6 Sitting height ratio; TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg10108389 chr3:44770937 ZNF501 -0.49 -4.83 -0.4 3.86e-6 Depressive symptoms; TGCT cis rs6912958 0.712 rs2754262 chr6:88405585 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.51 -4.83 -0.4 3.86e-6 Monocyte percentage of white cells; TGCT cis rs13102973 0.720 rs7672296 chr4:135890056 C/G cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs7674212 0.510 rs6856593 chr4:104177699 T/C cg16532752 chr4:104119610 CENPE -0.52 -4.76 -0.39 5.34e-6 Type 2 diabetes; TGCT cis rs1395 0.922 rs11898114 chr2:27515527 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.47 6.13 0.48 1.09e-8 Blood metabolite levels; TGCT cis rs1018836 0.923 rs10956720 chr8:91576222 C/T cg16814680 chr8:91681699 NA -0.91 -10.17 -0.67 5.03e-18 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7714584 0.590 rs4352593 chr5:150269332 T/C cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs17767294 0.708 rs72845062 chr6:27653578 C/T cg08851530 chr6:28072375 NA 1.55 6.56 0.51 1.32e-9 Parkinson's disease; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg16325326 chr1:53192061 ZYG11B 0.61 6.62 0.51 9.84e-10 Monocyte count; TGCT cis rs2658782 0.724 rs2605627 chr11:93259515 A/G cg15737290 chr11:93063684 CCDC67 0.7 5.24 0.43 6.65e-7 Pulmonary function decline; TGCT cis rs910187 0.678 rs6122564 chr20:45814745 A/C cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs11785400 0.793 rs13248524 chr8:143739343 T/C cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg06108461 chr20:60628389 TAF4 -0.71 -10.44 -0.68 1.08e-18 Body mass index; TGCT cis rs55794721 0.509 rs12027110 chr1:25775682 A/T cg23205692 chr1:25664452 TMEM50A 0.48 5.02 0.41 1.74e-6 Plateletcrit;Mean corpuscular volume; TGCT cis rs7552404 0.655 rs1146646 chr1:76265500 G/A cg10523679 chr1:76189770 ACADM 0.68 6.71 0.52 6.24e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs798554 0.759 rs2644309 chr7:2889034 T/C cg13628971 chr7:2884303 GNA12 0.56 4.48 0.37 1.69e-5 Height; TGCT cis rs1580019 0.587 rs7804457 chr7:32557981 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.98 0.41 2.05e-6 Cognitive ability; TGCT cis rs11249608 0.548 rs6859936 chr5:178451214 T/C cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs67478160 0.584 rs2295147 chr14:104195664 A/G cg26031613 chr14:104095156 KLC1 0.76 7.57 0.56 7.27e-12 Schizophrenia; TGCT trans rs1005277 0.579 rs1780122 chr10:38529509 C/A cg27523141 chr10:43048294 ZNF37B 0.73 8.5 0.61 5.09e-14 Extrinsic epigenetic age acceleration; TGCT cis rs1371867 0.875 rs1125706 chr8:101326739 T/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs7246657 0.943 rs2045908 chr19:37979768 C/G cg18154014 chr19:37997991 ZNF793 0.69 4.74 0.39 5.76e-6 Coronary artery calcification; TGCT cis rs1008375 0.931 rs979823 chr4:17700176 G/A cg10189774 chr4:17578691 LAP3 0.53 4.6 0.38 1.04e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs250677 0.522 rs6872172 chr5:148359529 G/C cg18129178 chr5:148520854 ABLIM3 0.36 4.69 0.39 7.23e-6 Breast cancer; TGCT cis rs11122272 0.735 rs2790873 chr1:231539685 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs9393692 0.905 rs989134 chr6:26336224 A/C cg05868516 chr6:26286170 HIST1H4H 0.58 5.45 0.44 2.63e-7 Educational attainment; TGCT trans rs7618501 0.633 rs13060128 chr3:50025028 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.38 0.64 3.95e-16 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.685 rs4556621 chr12:38187236 C/A cg13010199 chr12:38710504 ALG10B 0.62 4.9 0.4 2.87e-6 Bladder cancer; TGCT cis rs2576037 0.583 rs8094654 chr18:44527397 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.73 -0.39 5.92e-6 Personality dimensions; TGCT cis rs911186 0.740 rs6938200 chr6:27231150 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.57 -4.97 -0.41 2.14e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4242434 0.892 rs34269854 chr8:22465160 G/C cg21658235 chr8:22456391 C8orf58 0.43 4.47 0.37 1.72e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9916302 0.706 rs8067511 chr17:37611352 C/T cg07936489 chr17:37558343 FBXL20 -0.97 -7.39 -0.55 1.87e-11 Glomerular filtration rate (creatinine); TGCT cis rs2562456 0.876 rs11085468 chr19:21751889 C/T cg01304269 chr19:21688519 ZNF429 0.58 4.84 0.4 3.73e-6 Pain; TGCT trans rs6089829 0.925 rs11086152 chr20:61664656 T/C cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg18081338 chr6:17212963 NA 0.52 4.95 0.41 2.39e-6 Gambling; TGCT cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9467711 0.606 rs9358938 chr6:26387546 C/T cg10795676 chr6:26370623 BTN3A2 -0.48 -4.81 -0.4 4.33e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs3803170 0.513 rs4766572 chr12:111830765 G/A cg10833066 chr12:111807467 FAM109A 0.36 5.41 0.44 3.09e-7 Mean corpuscular hemoglobin; TGCT cis rs2797160 0.935 rs926855 chr6:126021782 A/G cg05901451 chr6:126070800 HEY2 0.74 6.21 0.49 7.18e-9 Endometrial cancer; TGCT cis rs4713118 0.955 rs9393848 chr6:27688369 C/T cg10876282 chr6:28092338 ZSCAN16 0.5 4.67 0.39 7.86e-6 Parkinson's disease; TGCT cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg02458000 chr6:26745757 NA 0.52 4.86 0.4 3.41e-6 Intelligence (multi-trait analysis); TGCT trans rs7726839 0.561 rs4957050 chr5:579066 A/C cg25482853 chr8:67687455 SGK3 1.05 9.29 0.64 6.67e-16 Obesity-related traits; TGCT trans rs1005277 0.502 rs2800484 chr10:38542415 C/T cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg24675658 chr1:53192096 ZYG11B 0.87 11.26 0.71 1.1e-20 Monocyte count; TGCT cis rs780096 0.527 rs12471703 chr2:27738854 C/T cg12000995 chr2:27665139 KRTCAP3 -0.37 -4.44 -0.37 1.98e-5 Total body bone mineral density; TGCT cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg20887711 chr4:1340912 KIAA1530 0.85 7.22 0.54 4.49e-11 Longevity; TGCT cis rs2797160 1.000 rs4897152 chr6:126002400 A/G cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs875971 0.540 rs35510581 chr7:65578777 G/A cg00343986 chr7:65444356 GUSB -0.24 -5.36 -0.43 3.86e-7 Aortic root size; TGCT cis rs8038465 1.000 rs67257650 chr15:73979507 C/T cg15420318 chr15:73925796 NPTN 0.69 6.44 0.5 2.36e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7267979 1.000 rs6050564 chr20:25344231 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6121246 0.559 rs6119652 chr20:30259445 C/G cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs12039431 0.589 rs61776186 chr1:38011993 G/C cg17933807 chr1:38061675 GNL2 -0.8 -7.69 -0.57 3.84e-12 Epithelial ovarian cancer; TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg08736216 chr1:53307985 ZYG11A -0.26 -4.99 -0.41 2.02e-6 Monocyte count; TGCT cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg04772025 chr11:68637568 NA 0.61 6.71 0.52 6.19e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9948 0.655 rs75763821 chr2:97392694 G/A cg01990225 chr2:97406019 LMAN2L -1.01 -5.01 -0.41 1.84e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs35306767 0.714 rs67696450 chr10:1090684 C/T cg26597838 chr10:835615 NA 0.61 7.09 0.54 8.8e-11 Eosinophil percentage of granulocytes; TGCT cis rs875971 1.000 rs1968225 chr7:65874773 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs8067545 1.000 rs8071730 chr17:19932731 C/T cg13482628 chr17:19912719 NA 0.53 4.48 0.37 1.66e-5 Schizophrenia; TGCT cis rs6952808 0.609 rs10232234 chr7:1948110 G/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.49 -0.44 2.18e-7 Bipolar disorder and schizophrenia; TGCT cis rs7918232 0.941 rs1755399 chr10:27394958 A/G cg14442939 chr10:27389572 ANKRD26 0.71 5.33 0.43 4.45e-7 Breast cancer; TGCT cis rs9682041 1.000 rs15709 chr3:170110529 T/A cg11886554 chr3:170076028 SKIL 0.83 6.37 0.5 3.41e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs2439831 0.681 rs1549523 chr15:43624189 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.04 8.86 0.62 7.03e-15 Lung cancer in ever smokers; TGCT cis rs2964802 0.505 rs13159419 chr5:10824302 C/A cg14521931 chr5:10832172 NA -0.28 -4.71 -0.39 6.44e-6 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs13108904 0.604 rs13103860 chr4:1320120 G/A cg13395646 chr4:1353034 KIAA1530 -0.52 -6.97 -0.53 1.64e-10 Obesity-related traits; TGCT cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs981844 0.890 rs62325113 chr4:154692555 A/G cg14289246 chr4:154710475 SFRP2 1.05 9.32 0.64 5.44e-16 Response to statins (LDL cholesterol change); TGCT cis rs1158570 0.814 rs7460225 chr8:131339373 A/G cg16277922 chr8:131349729 ASAP1 0.5 7.58 0.56 7.07e-12 Platelet count; TGCT cis rs9902453 0.904 rs9905638 chr17:28261022 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.26 0.6 1.9e-13 Coffee consumption (cups per day); TGCT cis rs3020736 0.500 rs4147640 chr22:42485292 T/C cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7191439 0.790 rs2306046 chr16:88781419 A/G cg27087555 chr16:88793112 FAM38A -0.43 -4.87 -0.4 3.4e-6 Plateletcrit; TGCT cis rs7226408 0.842 rs1863615 chr18:34348175 C/T cg06757138 chr18:34340585 FHOD3 0.24 4.86 0.4 3.54e-6 Obesity-related traits; TGCT cis rs2239547 0.603 rs6805298 chr3:53096552 A/G cg10802521 chr3:52805072 NEK4 0.6 5.46 0.44 2.52e-7 Schizophrenia; TGCT cis rs2050392 0.858 rs306583 chr10:30710057 C/T cg18806716 chr10:30721971 MAP3K8 0.45 5.33 0.43 4.45e-7 Inflammatory bowel disease; TGCT cis rs896854 0.517 rs9643353 chr8:95957063 A/G cg09323728 chr8:95962352 TP53INP1 0.43 5.01 0.41 1.82e-6 Type 2 diabetes; TGCT cis rs208520 1.000 rs72882086 chr6:66976671 G/A cg07460842 chr6:66804631 NA 0.81 7.16 0.54 6.31e-11 Exhaled nitric oxide output; TGCT cis rs709400 0.859 rs7693 chr14:104023704 C/T cg26031613 chr14:104095156 KLC1 1.18 16.51 0.83 4.23e-33 Body mass index; TGCT cis rs10865541 0.626 rs2324567 chr2:3386646 C/T cg01472464 chr2:3383078 TTC15;TSSC1 0.26 4.85 0.4 3.65e-6 Obesity-related traits; TGCT cis rs6952808 1.000 rs4449693 chr7:1884630 G/C cg22963979 chr7:1858916 MAD1L1 -0.36 -5.65 -0.45 1.05e-7 Bipolar disorder and schizophrenia; TGCT cis rs9640161 0.783 rs1132261 chr7:150059987 G/A cg21361702 chr7:150065534 REPIN1 0.51 4.62 0.38 9.46e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs6690583 0.623 rs111687161 chr1:85443533 A/G cg20280350 chr1:85513789 MCOLN3 -0.67 -4.5 -0.37 1.52e-5 Serum sulfate level; TGCT cis rs9291683 0.527 rs73212848 chr4:10093299 T/C cg00071950 chr4:10020882 SLC2A9 -0.54 -5.74 -0.46 6.75e-8 Bone mineral density; TGCT cis rs8028182 0.636 rs7184046 chr15:75866150 G/C cg20655648 chr15:75932815 IMP3 0.57 4.45 0.37 1.9e-5 Sudden cardiac arrest; TGCT trans rs1814175 0.745 rs7483456 chr11:49774613 C/T cg03929089 chr4:120376271 NA -0.69 -8.17 -0.59 3.03e-13 Height; TGCT trans rs9859260 0.744 rs419059 chr3:195782184 C/T cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs6121246 0.529 rs112367115 chr20:30178627 G/A cg18721089 chr20:30220636 NA -0.63 -6.68 -0.51 7.29e-10 Mean corpuscular hemoglobin; TGCT cis rs10193935 0.901 rs222488 chr2:42648570 T/G cg27598129 chr2:42591480 NA -0.33 -4.83 -0.4 4.02e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8064299 0.655 rs895691 chr17:72766300 G/T cg25054828 chr17:72772726 NAT9;TMEM104 0.63 5.8 0.46 5.28e-8 Monocyte count; TGCT cis rs559406 0.623 rs3826557 chr18:12843263 A/T cg23598886 chr18:12777645 NA 0.38 4.58 0.38 1.12e-5 Psoriasis; TGCT cis rs9527 0.501 rs12244388 chr10:104640052 G/A cg04362960 chr10:104952993 NT5C2 0.57 4.88 0.4 3.23e-6 Arsenic metabolism; TGCT cis rs7772486 0.875 rs854148 chr6:146310979 G/C cg23711669 chr6:146136114 FBXO30 0.89 9.5 0.65 2.02e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 1.000 rs7518038 chr1:76154430 G/A cg03433033 chr1:76189801 ACADM 0.82 9.81 0.66 3.67e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6088580 0.634 rs6088478 chr20:32971719 T/C cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs28595532 0.920 rs115986613 chr4:119752156 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg09177884 chr7:1199841 ZFAND2A -0.52 -4.98 -0.41 2.04e-6 Longevity;Endometriosis; TGCT cis rs2066819 1.000 rs11575232 chr12:56744422 G/A cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs7191439 0.858 rs4238685 chr16:88775220 T/C cg27087555 chr16:88793112 FAM38A -0.52 -5.99 -0.47 2.11e-8 Plateletcrit; TGCT cis rs35306767 0.855 rs34251037 chr10:867884 C/T cg20503657 chr10:835505 NA 0.77 11.28 0.71 9.73e-21 Eosinophil percentage of granulocytes; TGCT cis rs7547997 0.548 rs11264962 chr1:158328294 C/T cg03528325 chr1:158223921 CD1A 0.38 4.87 0.4 3.34e-6 QRS duration; TGCT cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.07e-5 Developmental language disorder (linguistic errors); TGCT cis rs4671400 0.516 rs1809028 chr2:61413723 A/G cg15711740 chr2:61764176 XPO1 -0.62 -4.53 -0.38 1.38e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs9911578 0.874 rs302874 chr17:56767996 A/G cg12560992 chr17:57184187 TRIM37 0.74 8.69 0.62 1.77e-14 Intelligence (multi-trait analysis); TGCT cis rs9858542 0.953 rs3811699 chr3:49396360 T/C cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs11690935 0.959 rs12692973 chr2:172642057 A/G cg13550731 chr2:172543902 DYNC1I2 1.2 13.02 0.76 5.79e-25 Schizophrenia; TGCT cis rs11105298 0.891 rs10858909 chr12:89935387 C/T cg00757033 chr12:89920650 WDR51B 0.3 4.71 0.39 6.56e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs734999 0.588 rs6701238 chr1:2520500 G/A cg18854424 chr1:2615690 NA 0.49 5.72 0.46 7.65e-8 Ulcerative colitis; TGCT trans rs61931739 0.500 rs28624237 chr12:34457171 G/T cg26384229 chr12:38710491 ALG10B 0.73 6.92 0.53 2.09e-10 Morning vs. evening chronotype; TGCT cis rs916888 0.773 rs199445 chr17:44817408 C/T cg01570182 chr17:44337453 NA 1.07 9.81 0.66 3.57e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2120019 0.938 rs13056 chr15:75312187 A/G cg17294928 chr15:75287854 SCAMP5 -0.79 -6.27 -0.49 5.46e-9 Blood trace element (Zn levels); TGCT cis rs60871478 0.636 rs56393680 chr7:885696 A/G cg22972055 chr7:872293 UNC84A 0.21 4.46 0.37 1.79e-5 Cerebrospinal P-tau181p levels; TGCT cis rs34014631 0.688 rs36018485 chr10:103581114 T/C cg22630918 chr10:102748988 C10orf2 0.34 4.56 0.38 1.21e-5 Coronary artery calcification; TGCT cis rs4713118 0.513 rs149958 chr6:28013617 A/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.75 0.39 5.48e-6 Parkinson's disease; TGCT cis rs6540559 0.546 rs735694 chr1:210034029 T/C cg21951975 chr1:209979733 IRF6 0.69 5.18 0.42 8.74e-7 Cleft lip with or without cleft palate; TGCT cis rs67478160 0.643 rs12880167 chr14:104300829 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.51 -0.5 1.67e-9 Schizophrenia; TGCT cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg06636001 chr8:8085503 FLJ10661 -0.8 -8.39 -0.6 9.17e-14 Neuroticism; TGCT cis rs9894429 0.646 rs9902264 chr17:79613828 G/A cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs12484776 0.729 rs8136149 chr22:40532484 C/T cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs651907 0.535 rs11716558 chr3:101528481 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.47 0.68 9.24e-19 Colorectal cancer; TGCT cis rs7267979 0.739 rs6138555 chr20:25242910 G/A cg14121845 chr20:25566513 NINL 0.49 4.96 0.41 2.24e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7651736 1.000 rs7651736 chr3:136760598 A/G cg21827317 chr3:136751795 NA 0.35 4.92 0.4 2.67e-6 Neuroticism; TGCT cis rs514406 0.825 rs28817407 chr1:53226116 G/A cg25767906 chr1:53392781 SCP2 0.48 5.56 0.45 1.57e-7 Monocyte count; TGCT cis rs4665809 1.000 rs17040322 chr2:26351274 G/C cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs6840360 0.642 rs7676493 chr4:152426765 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs7940866 0.834 rs2324315 chr11:130839772 C/G cg05962950 chr11:130786565 SNX19 0.73 7.14 0.54 6.88e-11 Schizophrenia; TGCT cis rs12220898 0.749 rs7905866 chr10:50483552 T/C cg12697796 chr10:49954016 WDFY4 0.5 4.5 0.37 1.52e-5 Inflammatory biomarkers; TGCT cis rs986417 0.681 rs17097373 chr14:60826810 T/C cg27398547 chr14:60952738 C14orf39 -1.62 -7.58 -0.56 6.82e-12 Gut microbiota (bacterial taxa); TGCT cis rs782590 0.764 rs2586970 chr2:55829967 A/G cg18811423 chr2:55921094 PNPT1 0.55 5.72 0.46 7.65e-8 Metabolic syndrome; TGCT cis rs769267 0.929 rs2905421 chr19:19457908 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.34 0.49 3.96e-9 Tonsillectomy; TGCT cis rs9467773 1.000 rs1056667 chr6:26510564 T/C cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT cis rs9399135 0.636 rs4646871 chr6:135265617 A/G cg24558204 chr6:135376177 HBS1L -0.48 -5.21 -0.42 7.59e-7 Red blood cell count; TGCT cis rs17376456 0.825 rs28610997 chr5:93248374 T/C cg21475434 chr5:93447410 FAM172A 0.69 4.67 0.39 7.58e-6 Diabetic retinopathy; TGCT cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs12950390 0.530 rs11652510 chr17:45869644 C/G cg06532163 chr17:45867833 NA 0.31 5.32 0.43 4.68e-7 IgG glycosylation; TGCT cis rs9311474 0.502 rs4687624 chr3:52563572 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.83 0.4 3.88e-6 Electroencephalogram traits; TGCT cis rs6089584 0.821 rs4925332 chr20:60604639 C/T cg13770153 chr20:60521292 NA -0.54 -7.21 -0.54 4.83e-11 Body mass index; TGCT cis rs921968 0.643 rs711191 chr2:219386084 T/A cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs6426558 0.537 rs2492630 chr1:227286931 A/G cg10327440 chr1:227177885 CDC42BPA 0.6 7.29 0.55 3.18e-11 Neutrophil percentage of white cells; TGCT cis rs4727027 0.933 rs12704062 chr7:148827865 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4950928 0.823 rs10920579 chr1:203158972 A/G cg17014757 chr1:203156097 CHI3L1 -0.37 -4.73 -0.39 5.96e-6 YKL-40 levels; TGCT cis rs3772130 1.000 rs7427165 chr3:121364624 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.95 0.41 2.41e-6 Cognitive performance; TGCT cis rs13242816 1.000 rs62469031 chr7:116195841 A/G cg02799643 chr7:116139180 CAV2 -0.41 -5.21 -0.42 7.65e-7 P wave duration; TGCT cis rs514406 0.621 rs2003250 chr1:53196666 T/C cg24675658 chr1:53192096 ZYG11B 0.84 10.45 0.68 1.03e-18 Monocyte count; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg04389838 chr3:44770851 ZNF501 -0.39 -5.03 -0.41 1.66e-6 Depressive symptoms; TGCT cis rs639012 0.599 rs472486 chr11:85831690 A/G cg07180834 chr11:85838833 NA -0.31 -4.47 -0.37 1.72e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg12310025 chr6:25882481 NA 0.9 9.29 0.64 6.69e-16 Blood metabolite levels; TGCT trans rs57221529 0.563 rs4957057 chr5:569230 C/G cg11887960 chr12:57824829 NA 1.02 7.74 0.57 3.07e-12 Lung disease severity in cystic fibrosis; TGCT cis rs9952991 0.883 rs2542148 chr18:12777573 C/G cg23598886 chr18:12777645 NA 0.62 5.78 0.46 5.63e-8 Inflammatory skin disease; TGCT cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs12682352 0.715 rs332039 chr8:8723651 C/G cg15556689 chr8:8085844 FLJ10661 0.57 5.18 0.42 8.87e-7 Neuroticism; TGCT cis rs73198271 0.694 rs73201840 chr8:8647067 G/T cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs56702977 1 rs56702977 chr15:42671308 G/A cg20699549 chr15:42567973 GANC 0.23 4.44 0.37 1.98e-5 Fibrinogen levels; TGCT cis rs7103648 0.712 rs10838703 chr11:47422861 C/G cg20307385 chr11:47447363 PSMC3 0.96 10.55 0.69 5.69e-19 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.68e-9 Blood metabolite levels; TGCT cis rs72781680 1.000 rs72796328 chr2:24141343 A/G cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs7666738 0.800 rs10008654 chr4:98820498 C/A cg17366294 chr4:99064904 C4orf37 0.7 7.45 0.56 1.42e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs801193 1.000 rs2659906 chr7:66165310 T/C cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs9914988 0.943 rs7215000 chr17:27088436 C/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9894429 0.789 rs35887231 chr17:79587126 G/A cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs910316 1.000 rs175443 chr14:75601963 C/T cg08847533 chr14:75593920 NEK9 -0.94 -10.33 -0.68 2.03e-18 Height; TGCT cis rs1406084 0.636 rs4581850 chr2:154718003 A/C cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg19318889 chr4:1322082 MAEA 0.2 5.04 0.41 1.63e-6 Longevity; TGCT cis rs909674 0.818 rs5757681 chr22:39845547 A/G cg01416388 chr22:39784598 NA -0.69 -6.29 -0.49 4.85e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs3749237 0.595 rs4955412 chr3:49418168 A/C cg07636037 chr3:49044803 WDR6 0.64 6.04 0.48 1.63e-8 Resting heart rate; TGCT cis rs2836974 0.565 rs34304022 chr21:40579619 G/A cg11890956 chr21:40555474 PSMG1 0.93 6.97 0.53 1.66e-10 Cognitive function; TGCT cis rs7192750 0.586 rs8054175 chr16:71990424 G/A cg06353428 chr16:71660113 MARVELD3 0.73 6.21 0.49 7.34e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs1008375 0.900 rs13144986 chr4:17675019 C/A cg16339924 chr4:17578868 LAP3 -0.6 -5.02 -0.41 1.75e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs16867321 0.614 rs12693245 chr2:181445110 T/C cg23363182 chr2:181467187 NA 0.41 6.04 0.48 1.69e-8 Obesity; TGCT trans rs7618501 0.669 rs2230590 chr3:49936102 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.89 9.83 0.66 3.19e-17 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.867 rs16957630 chr15:43642780 A/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs4862750 0.914 rs7658351 chr4:187875680 G/T cg22105103 chr4:187893119 NA 0.32 4.51 0.38 1.5e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs56235845 0.964 rs11741640 chr5:176792743 G/A cg17509989 chr5:176798049 RGS14 0.78 12.32 0.74 2.93e-23 Hemoglobin concentration;Hematocrit; TGCT cis rs12701220 0.847 rs10272002 chr7:1047615 A/G cg27454412 chr7:1067447 C7orf50 -0.48 -4.44 -0.37 1.98e-5 Bronchopulmonary dysplasia; TGCT cis rs4665809 0.590 rs7606351 chr2:26292545 A/C cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs2120019 1.000 rs2415255 chr15:75332412 A/G cg11632617 chr15:75315747 PPCDC -0.3 -4.47 -0.37 1.71e-5 Blood trace element (Zn levels); TGCT cis rs832540 0.801 rs7731700 chr5:56111927 C/T cg12311346 chr5:56204834 C5orf35 -0.49 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs921968 0.643 rs3770218 chr2:219525335 C/T cg02176678 chr2:219576539 TTLL4 0.38 5.47 0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs523522 0.962 rs655530 chr12:121022275 T/C cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs864537 0.676 rs1773561 chr1:167421951 C/T cg22356347 chr1:167427500 CD247 -0.21 -5.34 -0.43 4.24e-7 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs9467711 0.651 rs34888489 chr6:26073375 C/A cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs2663905 0.611 rs2663924 chr15:81392903 T/G cg09888468 chr15:81410853 NA -0.61 -5.07 -0.41 1.43e-6 QT interval (drug interaction); TGCT cis rs7586879 0.639 rs7567997 chr2:25096952 A/G cg15423357 chr2:25149977 NA 0.47 4.56 0.38 1.2e-5 Body mass index; TGCT cis rs9906944 0.864 rs9902512 chr17:47094274 C/G cg20966754 chr17:47091339 IGF2BP1 -0.43 -4.88 -0.4 3.21e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg08859206 chr1:53392774 SCP2 -0.41 -6.28 -0.49 5.12e-9 Monocyte count; TGCT cis rs9393692 0.875 rs9358917 chr6:26284417 T/C cg00631329 chr6:26305371 NA -0.41 -6.09 -0.48 1.34e-8 Educational attainment; TGCT cis rs1371867 0.817 rs1788185 chr8:101335529 T/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs2013441 1.000 rs4924810 chr17:20071819 T/C cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs60843830 1.000 rs62114501 chr2:231741 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.73 6.93 0.53 1.99e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs478304 0.651 rs10896038 chr11:65505528 G/C cg17480646 chr11:65405466 SIPA1 -0.57 -6.95 -0.53 1.84e-10 Acne (severe); TGCT trans rs324780 0.504 rs3110191 chr12:83909897 A/G cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.42e-10 Vertical cup-disc ratio; TGCT cis rs3027009 0.881 rs56184975 chr1:159149253 G/T cg18972751 chr1:158261555 CD1C -0.46 -4.81 -0.4 4.27e-6 Lean body mass and age at menarche (combined); TGCT cis rs4149423 1.000 rs12620050 chr2:108919798 G/A cg25838818 chr2:108905173 SULT1C2 -0.43 -7.22 -0.54 4.58e-11 Lobe size; TGCT cis rs17376456 0.569 rs10067754 chr5:93093110 T/A cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs7582180 0.614 rs4850931 chr2:101005145 C/T cg14675211 chr2:100938903 LONRF2 0.51 4.85 0.4 3.6e-6 Intelligence (multi-trait analysis); TGCT cis rs644799 0.710 rs564480 chr11:95561741 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.78 8.58 0.61 3.3e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9911578 1.000 rs12936058 chr17:57017420 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.586 rs6050429 chr20:25183058 G/A cg14121845 chr20:25566513 NINL 0.45 4.88 0.4 3.23e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12497850 1.000 rs4858798 chr3:48727112 C/T cg16497277 chr3:49208875 KLHDC8B -0.49 -4.67 -0.39 7.79e-6 Parkinson's disease; TGCT cis rs769267 0.965 rs2965188 chr19:19522557 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.65 5.4 0.44 3.25e-7 Tonsillectomy; TGCT cis rs11718455 0.767 rs6771202 chr3:43990087 A/T cg08738300 chr3:44038990 NA 0.74 5.62 0.45 1.22e-7 Coronary artery disease; TGCT cis rs7772486 0.727 rs4896843 chr6:146063451 T/C cg05347473 chr6:146136440 FBXO30 -0.53 -4.91 -0.4 2.81e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1801251 1.000 rs778166 chr2:233664097 A/T cg25237894 chr2:233734115 C2orf82 0.31 5.49 0.44 2.17e-7 Coronary artery disease; TGCT cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs8180040 0.620 rs2305635 chr3:47043622 G/A cg27129171 chr3:47204927 SETD2 -0.7 -8.36 -0.6 1.09e-13 Colorectal cancer; TGCT cis rs9527 0.590 rs10883820 chr10:104764661 A/C cg15744005 chr10:104629667 AS3MT 0.42 4.92 0.4 2.74e-6 Arsenic metabolism; TGCT cis rs66573146 0.831 rs56031152 chr4:6973832 C/A cg05069807 chr4:6945702 TBC1D14 0.32 5.01 0.41 1.83e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs13424612 1.000 rs10189996 chr2:240908800 G/A cg26363272 chr2:240904871 NDUFA10 0.29 4.85 0.4 3.58e-6 Odorant perception (isobutyraldehyde); TGCT cis rs1865760 0.602 rs9467662 chr6:26021327 G/A cg16482183 chr6:26056742 HIST1H1C 0.56 4.78 0.39 4.96e-6 Height; TGCT cis rs9549260 0.620 rs12583418 chr13:41195411 G/A cg21288729 chr13:41239152 FOXO1 1.0 10.25 0.68 3.06e-18 Red blood cell count; TGCT cis rs4700695 0.719 rs27077 chr5:65445342 C/T cg21114390 chr5:65439923 SFRS12 0.84 7.56 0.56 7.85e-12 Facial morphology (factor 19); TGCT cis rs7819412 0.745 rs2898260 chr8:10939490 G/T cg21775007 chr8:11205619 TDH -0.51 -4.92 -0.4 2.64e-6 Triglycerides; TGCT cis rs9902453 0.765 rs3102560 chr17:28029938 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.39 0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs899997 0.862 rs57260218 chr15:78973772 C/T cg04896959 chr15:78267971 NA -0.32 -4.57 -0.38 1.18e-5 Coronary artery disease or large artery stroke; TGCT cis rs6840360 0.571 rs11931934 chr4:152552082 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs2013441 1.000 rs2703778 chr17:20138900 T/C cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs9814567 0.806 rs4074522 chr3:134325626 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.77 6.92 0.53 2.15e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3820068 0.581 rs58425551 chr1:15922518 A/G cg05660106 chr1:15850417 CASP9 0.83 8.29 0.6 1.58e-13 Systolic blood pressure; TGCT cis rs7666738 0.830 rs13140676 chr4:98804978 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.75 0.46 6.46e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2239547 0.522 rs9831409 chr3:52985711 A/T cg10802521 chr3:52805072 NEK4 0.64 6.06 0.48 1.48e-8 Schizophrenia; TGCT cis rs12681288 0.676 rs2701901 chr8:1017816 G/C cg04851639 chr8:1020857 NA -0.36 -6.79 -0.52 4.13e-10 Schizophrenia; TGCT trans rs916888 0.821 rs70600 chr17:44860021 C/T cg01341218 chr17:43662625 NA 1.11 9.34 0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10088262 0.591 rs13270541 chr8:124794849 G/A cg20713898 chr8:124780851 FAM91A1 -0.84 -7.19 -0.54 5.3e-11 Pancreatic cancer; TGCT cis rs950880 0.542 rs1558621 chr2:102930307 A/G cg09003973 chr2:102972529 NA -0.53 -4.69 -0.39 6.95e-6 Serum protein levels (sST2); TGCT cis rs6964587 1.000 rs7784248 chr7:91758111 A/G cg17063962 chr7:91808500 NA 0.87 9.26 0.64 7.86e-16 Breast cancer; TGCT cis rs11648796 0.757 rs3809666 chr16:764753 C/G cg07343612 chr16:622815 PIGQ -0.35 -4.99 -0.41 2.01e-6 Height; TGCT cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg02187348 chr16:89574699 SPG7 -0.58 -6.18 -0.49 8.34e-9 Multiple myeloma (IgH translocation); TGCT cis rs6500602 0.627 rs709632 chr16:4587811 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.39 -5.7 -0.46 8.2e-8 Schizophrenia; TGCT cis rs13191362 1.000 rs28360546 chr6:163210973 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.76 4.8 0.4 4.57e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs1496653 0.557 rs34443476 chr3:23350466 G/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs28374715 0.578 rs17730888 chr15:41637547 A/G cg18705301 chr15:41695430 NDUFAF1 -0.94 -15.72 -0.82 2.7e-31 Ulcerative colitis; TGCT cis rs1801251 0.711 rs2592117 chr2:233735693 C/T cg25237894 chr2:233734115 C2orf82 -0.29 -5.63 -0.45 1.14e-7 Coronary artery disease; TGCT cis rs6427419 0.934 rs6427420 chr1:158066834 A/G cg07184316 chr1:157669111 FCRL3 0.26 4.86 0.4 3.52e-6 Obesity-related traits; TGCT cis rs11098499 0.909 rs28571712 chr4:120375980 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs727505 1.000 rs68091803 chr7:124526331 C/T cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs7772486 0.790 rs7753833 chr6:146161432 C/A cg05347473 chr6:146136440 FBXO30 0.51 4.79 0.4 4.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12900413 0.562 rs2118849 chr15:90302399 G/T cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2228479 0.681 rs3212346 chr16:89982358 G/A cg06558623 chr16:89946397 TCF25 0.44 5.91 0.47 3.15e-8 Skin colour saturation; TGCT cis rs3776081 0.537 rs58746386 chr5:149530269 T/C cg18424208 chr5:149546337 CDX1 -0.25 -4.64 -0.38 8.8e-6 Blood protein levels; TGCT cis rs912057 0.965 rs1294409 chr6:6738355 A/G cg06612196 chr6:6737390 NA -0.41 -5.11 -0.42 1.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs11195062 0.805 rs10884942 chr10:112016926 A/G cg00817464 chr10:111662876 XPNPEP1 -0.27 -4.69 -0.39 7.01e-6 Multiple myeloma; TGCT cis rs4851254 0.920 rs11123816 chr2:100783653 G/A cg23118464 chr2:100721844 AFF3 0.6 4.48 0.37 1.67e-5 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.716 rs9994641 chr4:99101605 C/T cg17366294 chr4:99064904 C4orf37 0.66 6.58 0.51 1.2e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg20569369 chr22:51173646 NA 0.32 5.29 0.43 5.29e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1577917 0.771 rs9294337 chr6:86248460 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 5.32 0.43 4.64e-7 Response to antipsychotic treatment; TGCT cis rs12579753 0.879 rs12829053 chr12:82161926 T/A cg21231944 chr12:82153410 PPFIA2 -0.34 -4.63 -0.38 8.95e-6 Resting heart rate; TGCT cis rs12135062 0.687 rs6685614 chr1:3108517 C/T cg21609526 chr1:3105151 PRDM16 0.34 5.4 0.44 3.32e-7 Migraine; TGCT cis rs3796352 1.000 rs13092352 chr3:52969697 C/T cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1577917 0.740 rs9450302 chr6:86289673 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.54 4.91 0.4 2.86e-6 Response to antipsychotic treatment; TGCT cis rs9818758 0.607 rs34580506 chr3:49113713 C/A cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs11098499 0.908 rs11098527 chr4:120399906 A/G cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs2439831 0.850 rs28509275 chr15:44098105 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.86 5.03 0.41 1.69e-6 Lung cancer in ever smokers; TGCT cis rs614226 1.000 rs541126 chr12:120972396 C/T cg01236616 chr12:121019343 POP5 -1.26 -13.2 -0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT cis rs78456975 0.628 rs13426896 chr2:1554768 C/T cg12573674 chr2:1569213 NA -0.48 -4.76 -0.39 5.23e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs804280 0.565 rs1466785 chr8:11623456 C/T cg26752888 chr8:11627280 NEIL2 -0.55 -4.99 -0.41 1.99e-6 Myopia (pathological); TGCT cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs3820928 0.874 rs10166736 chr2:227900419 C/T cg11843606 chr2:227700838 RHBDD1 -0.55 -4.96 -0.41 2.26e-6 Pulmonary function; TGCT cis rs8141529 0.764 rs5752807 chr22:29223169 A/G cg02153584 chr22:29168773 CCDC117 0.66 5.64 0.45 1.08e-7 Lymphocyte counts; TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg01802117 chr1:53393560 SCP2 -0.48 -5.77 -0.46 6.09e-8 Monocyte count; TGCT cis rs10197940 0.578 rs6718653 chr2:152346118 C/A cg06191203 chr2:152266755 RIF1 -0.61 -5.14 -0.42 1.03e-6 Lung cancer; TGCT cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg09222892 chr1:25734099 RHCE -0.42 -6.97 -0.53 1.68e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs2637266 0.745 rs2579732 chr10:78442778 T/C cg18941641 chr10:78392320 NA 0.37 4.47 0.37 1.73e-5 Pulmonary function; TGCT cis rs7100689 0.646 rs11202751 chr10:82147802 G/A cg01528321 chr10:82214614 TSPAN14 0.79 7.93 0.58 1.11e-12 Post bronchodilator FEV1; TGCT cis rs9303401 0.614 rs34058624 chr17:57118121 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.65 6.06 0.48 1.54e-8 Cognitive test performance; TGCT cis rs7113874 0.569 rs4929942 chr11:8625096 A/G cg14521421 chr11:8862019 ST5 -0.31 -4.8 -0.4 4.44e-6 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs1348850 0.757 rs4893969 chr2:178478476 T/A cg22681709 chr2:178499509 PDE11A -0.47 -5.59 -0.45 1.35e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs71435601 0.600 rs572246 chr2:21385149 T/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs12136530 0.593 rs4911990 chr1:19731873 A/C cg24875000 chr1:19041556 PAX7 -0.25 -4.48 -0.37 1.66e-5 Lead levels in blood; TGCT cis rs4478858 0.684 rs7521463 chr1:31761936 T/A cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs3806843 0.576 rs246045 chr5:140329884 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10940138 0.779 rs62370675 chr5:67247975 G/A ch.5.1281357F chr5:67228439 NA 0.41 4.75 0.39 5.63e-6 Menarche (age at onset); TGCT cis rs796364 0.756 rs2949006 chr2:200715388 T/G cg17644776 chr2:200775616 C2orf69 0.29 4.49 0.37 1.58e-5 Schizophrenia; TGCT cis rs6424115 0.679 rs2267961 chr1:24071048 A/G cg15997130 chr1:24165203 NA -0.67 -6.16 -0.48 9.48e-9 Immature fraction of reticulocytes; TGCT cis rs7429990 0.932 rs12486714 chr3:48148700 C/G cg11946769 chr3:48343235 NME6 -0.56 -4.63 -0.38 9.27e-6 Educational attainment (years of education); TGCT cis rs78366141 0.649 rs7674009 chr4:89683324 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 -1.02 -5.28 -0.43 5.65e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs9443645 0.901 rs9343844 chr6:79586463 T/A cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.624 rs303444 chr10:30729347 C/T cg13289132 chr10:30722225 MAP3K8 -0.46 -5.61 -0.45 1.27e-7 Inflammatory bowel disease; TGCT trans rs7726839 0.561 rs56410216 chr5:583216 C/A cg11887960 chr12:57824829 NA 0.98 7.81 0.57 2.09e-12 Obesity-related traits; TGCT cis rs7659604 0.539 rs3217773 chr4:122739121 A/G cg19748678 chr4:122722346 EXOSC9 0.9 9.35 0.64 4.81e-16 Type 2 diabetes; TGCT cis rs7635838 0.617 rs346075 chr3:11294027 T/G cg00170343 chr3:11313890 ATG7 0.64 6.43 0.5 2.5e-9 HDL cholesterol; TGCT cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg22029157 chr1:209979665 IRF6 0.81 6.42 0.5 2.67e-9 Cleft lip with or without cleft palate; TGCT cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.95 7.54 0.56 8.47e-12 Platelet count; TGCT cis rs1552244 0.515 rs67342818 chr3:10166406 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs10197940 0.648 rs7587301 chr2:152347600 A/G cg06191203 chr2:152266755 RIF1 -0.61 -5.16 -0.42 9.68e-7 Lung cancer; TGCT cis rs79518236 1 rs79518236 chr7:98026554 ACT/A cg09267113 chr7:98030324 BAIAP2L1 -0.95 -8.89 -0.62 5.83e-15 Breast cancer; TGCT cis rs13108904 0.517 rs4974551 chr4:1336410 C/A cg03303774 chr4:1407052 NA 0.38 6.07 0.48 1.45e-8 Obesity-related traits; TGCT cis rs739496 0.527 rs11066090 chr12:112365523 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs7172809 0.573 rs11854182 chr15:77448977 T/C cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg03517284 chr6:25882590 NA -0.65 -5.81 -0.46 4.87e-8 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.765 rs2447935 chr17:28057524 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.39 -0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs6840360 1.000 rs12502055 chr4:152596668 G/A cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs992157 0.835 rs34353396 chr2:219153982 T/C cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT cis rs10791097 0.592 rs7116068 chr11:130732739 A/C cg14779329 chr11:130786720 SNX19 -0.26 -4.59 -0.38 1.09e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7772486 0.743 rs1292339 chr6:145967086 C/T cg23711669 chr6:146136114 FBXO30 -0.8 -8.47 -0.61 5.92e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs3809566 0.597 rs9806545 chr15:63328490 C/T cg00520135 chr15:63333846 TPM1 -0.42 -5.16 -0.42 9.55e-7 Platelet count; TGCT cis rs854765 0.663 rs1108648 chr17:17750558 G/A cg09796270 chr17:17721594 SREBF1 -0.3 -5.85 -0.46 4.18e-8 Total body bone mineral density; TGCT cis rs9329289 0.510 rs28579610 chr10:2546080 C/A cg07014206 chr10:2547000 NA -0.28 -4.66 -0.39 8.13e-6 Age-related hearing impairment; TGCT cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg07061783 chr6:25882402 NA 0.64 6.7 0.52 6.57e-10 Blood metabolite levels; TGCT cis rs7666738 0.791 rs17549003 chr4:98969132 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2832191 0.967 rs2251377 chr21:30530599 T/C cg24692254 chr21:30365293 RNF160 0.75 7.4 0.55 1.78e-11 Dental caries; TGCT cis rs7523050 0.643 rs12741359 chr1:109400489 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs231513 0.954 rs231497 chr17:41975947 A/G cg26893861 chr17:41843967 DUSP3 -0.71 -5.29 -0.43 5.46e-7 Cognitive function; TGCT cis rs6912958 0.516 rs242278 chr6:88047059 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.47 6.29 0.49 5.04e-9 Monocyte percentage of white cells; TGCT cis rs7647973 0.961 rs4955430 chr3:49378088 G/A cg07636037 chr3:49044803 WDR6 0.72 5.84 0.46 4.25e-8 Menarche (age at onset); TGCT cis rs3733585 0.605 rs7656624 chr4:10121097 T/C cg11266682 chr4:10021025 SLC2A9 -0.56 -6.6 -0.51 1.08e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs28374715 0.578 rs7165914 chr15:41632451 C/T cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.93 -0.8 1.76e-29 Ulcerative colitis; TGCT cis rs492146 0.765 rs672281 chr6:52844045 G/A cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs1371867 0.846 rs1660347 chr8:101314980 G/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs7666738 0.830 rs58696666 chr4:99006913 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7809950 0.784 rs7803102 chr7:107248929 T/G cg23024343 chr7:107201750 COG5 0.33 5.23 0.42 7.11e-7 Coronary artery disease; TGCT cis rs12477438 1.000 rs12466388 chr2:99916538 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.78 -0.62 1.12e-14 Chronic sinus infection; TGCT cis rs12049351 0.774 rs754022 chr1:229637645 C/A cg12130225 chr1:229698885 NA 0.39 4.58 0.38 1.12e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs6433857 0.536 rs1542035 chr2:181351114 T/C cg23363182 chr2:181467187 NA -0.32 -4.85 -0.4 3.59e-6 Body mass index; TGCT cis rs9325144 0.600 rs12424410 chr12:38758035 A/T cg26384229 chr12:38710491 ALG10B -0.62 -5.77 -0.46 5.9e-8 Morning vs. evening chronotype; TGCT cis rs2637266 1.000 rs2894339 chr10:78354104 G/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT trans rs208520 0.837 rs208488 chr6:66926902 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.05 -0.67 9.41e-18 Exhaled nitric oxide output; TGCT cis rs7918232 0.627 rs10829165 chr10:27319465 A/G cg14442939 chr10:27389572 ANKRD26 0.56 4.67 0.39 7.8e-6 Breast cancer; TGCT cis rs11731606 0.508 rs17376943 chr4:95277117 G/A cg00507259 chr4:95128692 SMARCAD1 0.65 4.89 0.4 3.02e-6 Mean platelet volume; TGCT cis rs9894429 1.000 rs9674872 chr17:79581931 T/A cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs950169 1.000 rs34751999 chr15:84758419 T/C cg17173187 chr15:85201210 NMB 0.47 5.23 0.43 7.01e-7 Schizophrenia; TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg21862992 chr11:68658383 NA 0.49 6.79 0.52 4.13e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg04287289 chr16:89883240 FANCA 0.68 6.76 0.52 4.83e-10 Vitiligo; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg00024416 chr22:24240387 NA -0.29 -5.18 -0.42 8.65e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6061231 0.834 rs2427311 chr20:60970123 A/G cg24112000 chr20:60950667 NA -0.35 -4.79 -0.4 4.58e-6 Colorectal cancer; TGCT cis rs875971 0.660 rs10281080 chr7:66042441 T/C cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs7412746 0.658 rs11589458 chr1:150792616 A/G cg04414720 chr1:150670196 GOLPH3L 0.42 5.35 0.43 4.06e-7 Melanoma; TGCT cis rs694419 0.602 rs9951519 chr18:60166419 G/C cg13506219 chr18:60193840 ZCCHC2 -0.54 -4.84 -0.4 3.86e-6 Serum albumin level; TGCT cis rs1846974 1 rs1846974 chr5:87969927 G/A cg24804195 chr5:87968844 LOC645323 0.77 4.58 0.38 1.11e-5 Body mass index; TGCT cis rs9916302 0.706 rs9893735 chr17:37469858 A/C cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs367615 0.704 rs7726991 chr5:108847434 C/T cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs55720021 1 rs55720021 chr19:49144241 G/T cg07996880 chr19:49339085 HSD17B14 0.27 4.58 0.38 1.09e-5 Lymphocyte percentage of white cells;Neutrophil percentage of white cells; TGCT cis rs4523957 0.583 rs2641444 chr17:2037402 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs556990 0.574 rs473598 chr13:113801189 C/T cg00619561 chr13:112980676 NA -0.29 -4.79 -0.4 4.67e-6 Blood protein levels; TGCT cis rs9346649 0.933 rs9364398 chr6:168489433 G/T cg02770688 chr6:168491649 NA -0.27 -4.9 -0.4 2.92e-6 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs9611519 0.964 rs2092563 chr22:41592677 G/A cg13695892 chr22:41940480 POLR3H -0.51 -4.56 -0.38 1.22e-5 Neuroticism; TGCT cis rs80282103 0.618 rs17155886 chr10:1145182 A/G cg18964960 chr10:1102726 WDR37 0.98 4.57 0.38 1.15e-5 Glomerular filtration rate (creatinine); TGCT cis rs17068510 0.572 rs11779787 chr8:3883394 C/T cg25338036 chr8:3047536 CSMD1 -0.44 -4.57 -0.38 1.18e-5 Cerebrospinal fluid clusterin levels; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg11494091 chr17:61959527 GH2 -0.61 -15.24 -0.81 3.34e-30 Prudent dietary pattern; TGCT cis rs950169 0.840 rs62029595 chr15:84955301 C/T cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT trans rs8073060 0.855 rs12150450 chr17:33868896 A/T cg19694781 chr19:47549865 TMEM160 0.42 7.72 0.57 3.37e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2204008 0.905 rs7294297 chr12:38442573 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.46 0.56 1.32e-11 Bladder cancer; TGCT cis rs12134133 0.752 rs57003024 chr1:207404344 T/C cg02152968 chr1:207494213 CD55 0.69 4.75 0.39 5.46e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs514406 0.861 rs2065477 chr1:53250213 C/T cg22166914 chr1:53195759 ZYG11B 0.42 7.25 0.55 3.97e-11 Monocyte count; TGCT cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg13395646 chr4:1353034 KIAA1530 -0.48 -6.31 -0.49 4.59e-9 Obesity-related traits; TGCT cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs1075232 0.826 rs60333545 chr15:31807319 G/C cg01030201 chr15:31746330 NA -1.07 -5.86 -0.47 3.84e-8 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs2204008 0.641 rs66876045 chr12:38205713 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.68 0.57 4.17e-12 Bladder cancer; TGCT cis rs17221829 0.528 rs2860553 chr11:89355296 A/G cg02982614 chr11:89391479 FOLH1B -0.27 -4.65 -0.39 8.2e-6 Anxiety in major depressive disorder; TGCT trans rs7618501 0.572 rs4688756 chr3:50040194 T/A cg21659725 chr3:3221576 CRBN 0.75 9.02 0.63 2.97e-15 Intelligence (multi-trait analysis); TGCT cis rs17473412 1.000 rs79535450 chr5:122713989 C/T cg15125798 chr5:122621645 NA -0.57 -5.13 -0.42 1.08e-6 Total body bone mineral density; TGCT cis rs10489202 0.583 rs201539 chr1:167995407 A/G cg24449463 chr1:168025552 DCAF6 -0.6 -7.13 -0.54 7.21e-11 Schizophrenia; TGCT trans rs561341 1.000 rs560132 chr17:30320019 C/T cg20587970 chr11:113659929 NA -1.03 -12.17 -0.74 6.53e-23 Hip circumference adjusted for BMI; TGCT cis rs9926296 0.632 rs9935559 chr16:89800529 C/T cg08627397 chr16:89984028 MC1R 0.3 4.75 0.39 5.52e-6 Vitiligo; TGCT cis rs6424115 1.000 rs12031592 chr1:24127864 A/C cg15997130 chr1:24165203 NA 0.89 10.03 0.67 1.08e-17 Immature fraction of reticulocytes; TGCT cis rs447735 0.537 rs7190341 chr16:89917537 T/C cg04287289 chr16:89883240 FANCA 0.68 6.18 0.49 8.39e-9 Hemoglobin concentration; TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg02493798 chr17:6899577 ALOX12 0.43 4.91 0.4 2.87e-6 Tonsillectomy; TGCT cis rs6088580 0.634 rs4911153 chr20:32961547 C/T cg06115741 chr20:33292138 TP53INP2 -0.53 -4.75 -0.39 5.59e-6 Glomerular filtration rate (creatinine); TGCT cis rs698813 0.674 rs11678787 chr2:44496315 C/T cg00619915 chr2:44497795 NA -0.24 -5.52 -0.44 1.91e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs7829975 0.714 rs11777085 chr8:8672429 G/C cg15556689 chr8:8085844 FLJ10661 0.66 6.12 0.48 1.15e-8 Mood instability; TGCT cis rs611744 0.647 rs1584373 chr8:109263399 C/A cg21045802 chr8:109455806 TTC35 0.7 7.05 0.54 1.07e-10 Dupuytren's disease; TGCT trans rs17685 0.587 rs1623759 chr7:75724679 A/T cg19862616 chr7:65841803 NCRNA00174 0.49 7.91 0.58 1.24e-12 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7584330 0.910 rs6737914 chr2:238393434 A/G cg08992911 chr2:238395768 MLPH 0.64 5.24 0.43 6.81e-7 Prostate cancer; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg03724423 chr7:27170755 HOXA4 -0.46 -4.74 -0.39 5.86e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs892961 0.932 rs11657725 chr17:75405501 G/C cg05865280 chr17:75406074 SEPT9 0.29 6.76 0.52 4.91e-10 Airflow obstruction; TGCT cis rs28493229 0.522 rs2287692 chr19:41289756 G/A cg00475131 chr19:41117096 LTBP4 0.29 4.49 0.37 1.61e-5 Kawasaki disease; TGCT cis rs6987853 0.966 rs1901282 chr8:42392942 C/G cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg04944784 chr2:26401820 FAM59B -0.76 -6.34 -0.49 3.94e-9 Gut microbiome composition (summer); TGCT cis rs9916302 0.653 rs4239223 chr17:37717004 T/C cg03321784 chr17:37729644 NA 0.44 4.58 0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs2153535 0.580 rs9505446 chr6:8448691 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs7666738 0.830 rs28615340 chr4:98896922 T/C cg17366294 chr4:99064904 C4orf37 0.67 6.83 0.52 3.3e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs617219 0.710 rs16876598 chr5:78573970 T/C cg23987322 chr5:78407566 BHMT -0.35 -4.69 -0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg16680214 chr1:154839983 KCNN3 -0.35 -7.11 -0.54 8.04e-11 Prostate cancer; TGCT cis rs17607347 0.505 rs62051129 chr16:72453470 G/A cg06220725 chr16:72042591 DHODH -0.71 -4.71 -0.39 6.65e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg24829409 chr8:58192753 C8orf71 -0.55 -5.17 -0.42 9.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9926296 0.535 rs36022917 chr16:89893238 A/G cg01719998 chr16:89642051 CPNE7 -0.44 -4.46 -0.37 1.81e-5 Vitiligo; TGCT trans rs561341 0.883 rs7406056 chr17:30220224 C/T cg20587970 chr11:113659929 NA -0.8 -9.56 -0.65 1.44e-16 Hip circumference adjusted for BMI; TGCT cis rs72615157 0.634 rs2272343 chr7:99778285 A/C cg00814883 chr7:100076585 TSC22D4 -0.52 -5.14 -0.42 1.06e-6 Lung function (FEV1/FVC); TGCT cis rs9549367 0.789 rs12584981 chr13:113881185 T/C cg18105134 chr13:113819100 PROZ -0.34 -5.45 -0.44 2.63e-7 Platelet distribution width; TGCT cis rs10791323 0.519 rs329663 chr11:133754543 A/G cg03690763 chr11:133734501 NA -0.31 -5.33 -0.43 4.52e-7 Childhood ear infection; TGCT cis rs259282 0.813 rs259250 chr19:33149216 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.78 7.59 0.56 6.8e-12 Schizophrenia; TGCT cis rs8177253 0.965 rs1525889 chr3:133490033 A/C cg08439880 chr3:133502540 NA -0.31 -5.97 -0.47 2.29e-8 Iron status biomarkers; TGCT cis rs2710642 0.962 rs2058567 chr2:63091426 T/C cg17519650 chr2:63277830 OTX1 0.67 6.13 0.48 1.1e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs6988636 1.000 rs59834873 chr8:124188824 G/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs7681440 0.904 rs1822217 chr4:90765052 C/T cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs13040088 0.872 rs13039291 chr20:61572760 C/T cg23096297 chr20:61557774 DIDO1 1.18 9.71 0.66 6.5e-17 Menopause (age at onset); TGCT cis rs4819052 0.851 rs2838866 chr21:46713014 G/C cg06618935 chr21:46677482 NA -0.35 -5.57 -0.45 1.49e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7246657 0.722 rs16958861 chr19:38124179 G/A cg03611452 chr19:38183253 ZNF781 0.59 4.78 0.39 4.95e-6 Coronary artery calcification; TGCT cis rs2486012 0.737 rs541487 chr1:44283909 G/A cg12908607 chr1:44402522 ARTN -0.69 -5.2 -0.42 7.81e-7 Intelligence (multi-trait analysis); TGCT cis rs12681287 0.605 rs2976181 chr8:87344470 C/T cg27223183 chr8:87520930 FAM82B -0.67 -4.99 -0.41 1.97e-6 Caudate activity during reward; TGCT cis rs17784882 0.524 rs7433300 chr3:47120640 G/A cg27129171 chr3:47204927 SETD2 0.67 7.72 0.57 3.33e-12 QT interval; TGCT cis rs9527 0.590 rs7087459 chr10:104790999 T/C cg15744005 chr10:104629667 AS3MT -0.41 -4.8 -0.4 4.43e-6 Arsenic metabolism; TGCT cis rs7917772 0.599 rs2863717 chr10:104519829 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.57 -4.62 -0.38 9.3e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs62103177 0.525 rs9949598 chr18:77753037 G/A cg05926928 chr17:57297772 GDPD1 -0.74 -6.66 -0.51 7.78e-10 Opioid sensitivity; TGCT cis rs6032067 0.673 rs991048 chr20:43898227 C/T cg16667508 chr20:43936853 MATN4;RBPJL 0.45 6.77 0.52 4.51e-10 Blood protein levels; TGCT trans rs13270892 0.556 rs76217929 chr8:20472368 C/A cg14551562 chr9:130461838 NA -0.91 -6.7 -0.52 6.41e-10 Daytime sleep phenotypes; TGCT cis rs3806843 0.966 rs2563266 chr5:140136915 C/A cg19875535 chr5:140030758 IK -0.37 -6.32 -0.49 4.29e-9 Depressive symptoms (multi-trait analysis); TGCT trans rs9329221 0.741 rs56243511 chr8:9805695 T/C cg06636001 chr8:8085503 FLJ10661 -0.77 -6.93 -0.53 2.06e-10 Neuroticism; TGCT cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg03452623 chr4:187889614 NA -0.37 -5.56 -0.45 1.57e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.925 rs6122087 chr20:61664553 T/C cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs919433 0.713 rs2045245 chr2:198485341 A/C cg00792783 chr2:198669748 PLCL1 0.53 5.03 0.41 1.64e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs9467773 1.000 rs4713008 chr6:26538268 T/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs9733 0.519 rs10788792 chr1:150638572 T/G cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs10504229 1.000 rs59708460 chr8:58196526 G/A cg21724239 chr8:58056113 NA 0.38 4.75 0.39 5.6e-6 Developmental language disorder (linguistic errors); TGCT cis rs10949834 0.529 rs7785826 chr7:73548785 C/A cg07137043 chr7:73588983 EIF4H -0.67 -4.61 -0.38 9.97e-6 Verbal memory performance (residualized delayed recall change); TGCT cis rs2836974 0.681 rs8128827 chr21:40710547 C/T cg11644478 chr21:40555479 PSMG1 0.88 8.03 0.59 6.26e-13 Cognitive function; TGCT cis rs4975709 0.569 rs2077269 chr5:1863506 C/T cg14773178 chr5:1868261 NA 0.34 5.87 0.47 3.78e-8 Cardiovascular disease risk factors; TGCT cis rs67478160 0.619 rs2368560 chr14:104273311 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.42 -0.5 2.64e-9 Schizophrenia; TGCT cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.59 -5.94 -0.47 2.66e-8 Intelligence (multi-trait analysis); TGCT cis rs250677 0.687 rs250671 chr5:148446523 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs10927875 0.894 rs34957618 chr1:16320499 G/C cg14742211 chr1:16348397 CLCNKA -0.19 -4.48 -0.37 1.66e-5 Dilated cardiomyopathy; TGCT cis rs28595532 0.841 rs116452272 chr4:119770802 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs10131894 0.575 rs6574203 chr14:75429846 T/C cg06637938 chr14:75390232 RPS6KL1 0.56 4.81 0.4 4.26e-6 Coronary artery disease; TGCT cis rs12497850 0.931 rs9311432 chr3:48850443 T/A cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs11190604 1.000 rs2273694 chr10:102256496 G/T cg16342193 chr10:102329863 NA -0.41 -5.3 -0.43 5.07e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9910055 0.550 rs113844752 chr17:42297631 C/A cg19774624 chr17:42201019 HDAC5 -0.72 -6.64 -0.51 8.87e-10 Total body bone mineral density; TGCT cis rs7937682 0.924 rs501089 chr11:111502479 G/T cg09085632 chr11:111637200 PPP2R1B 1.0 9.51 0.65 1.98e-16 Primary sclerosing cholangitis; TGCT cis rs7639513 0.591 rs9849171 chr3:12622623 G/C cg23032965 chr3:12705835 RAF1 0.75 8.04 0.59 5.95e-13 Itch intensity from mosquito bite; TGCT cis rs752010 0.523 rs10890159 chr1:42118282 A/G cg06885757 chr1:42089581 HIVEP3 0.26 4.73 0.39 6.1e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs933688 0.536 rs332537 chr5:90794973 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.97 -6.22 -0.49 6.96e-9 Smoking behavior; TGCT cis rs3540 0.512 rs3930162 chr15:91075129 C/T cg22089800 chr15:90895588 ZNF774 -0.74 -7.58 -0.56 7.14e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg25703541 chr22:24373054 LOC391322 0.81 8.47 0.61 5.88e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg08736216 chr1:53307985 ZYG11A -0.28 -5.53 -0.44 1.83e-7 Monocyte count; TGCT cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg05552183 chr6:42928497 GNMT -0.53 -4.76 -0.39 5.35e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg03517284 chr6:25882590 NA -0.61 -5.6 -0.45 1.31e-7 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.846 rs1660346 chr8:101312497 A/G cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs1670533 1.000 rs633556 chr4:1092405 A/G cg27284194 chr4:1044797 NA 0.69 5.97 0.47 2.36e-8 Recombination rate (females); TGCT cis rs700651 0.789 rs5007118 chr2:198909738 G/C cg00792783 chr2:198669748 PLCL1 0.6 5.2 0.42 8.05e-7 Intracranial aneurysm; TGCT trans rs1005277 0.579 rs1740747 chr10:38520465 G/A cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs7635838 0.964 rs7624086 chr3:11412620 C/G cg00170343 chr3:11313890 ATG7 0.57 5.42 0.44 2.92e-7 HDL cholesterol; TGCT cis rs9393692 0.905 rs9393693 chr6:26277408 C/A cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.01e-7 Educational attainment; TGCT cis rs7249142 0.549 rs3787040 chr19:19297292 A/G cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.54 5.41 0.44 3.13e-7 IgG glycosylation; TGCT cis rs763014 0.932 rs2384972 chr16:674424 G/A cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.15e-6 Height; TGCT cis rs11112613 0.713 rs11112587 chr12:105941285 G/A cg03607813 chr12:105948248 NA 0.46 5.27 0.43 5.83e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs11671005 0.735 rs11084544 chr19:58940127 C/G cg13877915 chr19:58951672 ZNF132 0.65 5.13 0.42 1.09e-6 Mean platelet volume; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg25703541 chr22:24373054 LOC391322 -0.93 -10.82 -0.7 1.29e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7845219 0.544 rs4735330 chr8:95917770 A/C cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs4819052 1.000 rs13052356 chr21:46663588 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.87 7.26 0.55 3.73e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2439831 1.000 rs2251538 chr15:43767209 G/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs2235642 0.821 rs2281236 chr16:1603576 G/A cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.85 -0.46 4.15e-8 Coronary artery disease; TGCT cis rs13202913 0.652 rs9383578 chr6:151838192 C/T cg03627880 chr6:151815985 C6orf97 -0.55 -5.35 -0.43 4.1e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7772486 0.875 rs2748490 chr6:146329681 G/T cg05347473 chr6:146136440 FBXO30 0.49 4.7 0.39 6.88e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs6089829 0.962 rs57684920 chr20:61662639 G/A cg23505145 chr19:12996616 KLF1 -0.8 -8.25 -0.6 1.99e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs7917772 0.502 rs2296584 chr10:104244323 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4568518 0.530 rs4721672 chr7:17986098 T/C cg03009463 chr7:17980271 SNX13 0.57 4.61 0.38 1e-5 Measles; TGCT cis rs7945705 0.837 rs2742474 chr11:9002089 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -6.01 -0.47 1.93e-8 Hemoglobin concentration; TGCT cis rs7914558 0.966 rs11191518 chr10:104782853 C/G cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.67e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4494114 0.967 rs9438976 chr1:39353386 C/T cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.1e-9 Blood protein levels; TGCT cis rs3008870 1.000 rs2985821 chr1:67403787 G/A cg11518657 chr1:67396239 MIER1 0.54 4.68 0.39 7.24e-6 Lymphocyte percentage of white cells; TGCT cis rs11785400 1.000 rs4736342 chr8:143735190 A/G cg24634471 chr8:143751801 JRK 0.55 6.04 0.48 1.68e-8 Schizophrenia; TGCT cis rs4509693 0.782 rs7897782 chr10:102495856 C/A cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs9394841 0.667 rs3827633 chr6:41759846 A/C cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs6582630 0.502 rs3902522 chr12:38271203 T/C cg13010199 chr12:38710504 ALG10B 0.59 4.61 0.38 9.88e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs763121 0.853 rs2413546 chr22:39107001 G/A cg06022373 chr22:39101656 GTPBP1 0.74 7.23 0.54 4.37e-11 Menopause (age at onset); TGCT cis rs4975616 0.869 rs452932 chr5:1330253 T/C cg07493874 chr5:1342172 CLPTM1L -0.28 -6.88 -0.53 2.69e-10 Lung cancer; TGCT cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs763121 0.819 rs5757133 chr22:38947835 A/G cg06022373 chr22:39101656 GTPBP1 -0.77 -7.79 -0.57 2.27e-12 Menopause (age at onset); TGCT cis rs9467773 1.000 rs6930120 chr6:26555484 A/G cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg05985448 chr10:134359359 INPP5A 0.23 5.11 0.42 1.2e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2304206 0.614 rs12104272 chr19:50148052 A/G cg09250473 chr19:50168907 IRF3;BCL2L12 -0.77 -7.59 -0.56 6.52e-12 Vitiligo; TGCT cis rs1005277 0.522 rs1208684 chr10:38093936 G/A cg25427524 chr10:38739819 LOC399744 -0.32 -6.45 -0.5 2.22e-9 Extrinsic epigenetic age acceleration; TGCT cis rs919433 0.679 rs7600862 chr2:198534514 C/T cg00792783 chr2:198669748 PLCL1 0.55 4.93 0.4 2.56e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs713587 0.934 rs6738433 chr2:25159501 G/C cg15423357 chr2:25149977 NA 0.58 5.85 0.46 4.18e-8 Body mass index in non-asthmatics; TGCT cis rs7845219 0.539 rs13271644 chr8:95853948 A/G cg13393036 chr8:95962371 TP53INP1 -0.49 -5.8 -0.46 5.25e-8 Type 2 diabetes; TGCT cis rs9926296 0.656 rs11861084 chr16:89875710 G/T cg04287289 chr16:89883240 FANCA -0.71 -7.02 -0.53 1.3100000000000001e-10 Vitiligo; TGCT cis rs7267979 0.816 rs1044573 chr20:25206654 A/G cg03522245 chr20:25566470 NINL 0.47 4.53 0.38 1.35e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1008375 1.000 rs6848360 chr4:17634442 G/T cg10189774 chr4:17578691 LAP3 0.65 5.64 0.45 1.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6701037 0.566 rs13373754 chr1:175139275 C/A cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs72781680 0.706 rs72796108 chr2:23904990 C/A cg08917208 chr2:24149416 ATAD2B 1.0 5.56 0.45 1.59e-7 Lymphocyte counts; TGCT cis rs2066819 1.000 rs59626664 chr12:56636975 C/G cg26714650 chr12:56694279 CS -1.32 -6.2 -0.49 7.69e-9 Psoriasis vulgaris; TGCT cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs4727027 0.631 rs62507511 chr7:148796080 C/A cg23583168 chr7:148888333 NA -0.68 -8.44 -0.6 6.95e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg08736216 chr1:53307985 ZYG11A -0.3 -6.06 -0.48 1.48e-8 Monocyte count; TGCT cis rs12510870 0.566 rs9999939 chr4:74454004 C/T cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs6835098 0.962 rs10014010 chr4:174083230 C/T cg08422745 chr4:174089978 GALNT7 -0.93 -10.95 -0.7 6.1e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs6565180 0.888 rs12447833 chr16:30390314 T/C cg17640201 chr16:30407289 ZNF48 0.92 8.6 0.61 2.9e-14 Tonsillectomy; TGCT cis rs7829975 0.577 rs79495969 chr8:8545250 G/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.17 -0.42 9.06e-7 Mood instability; TGCT cis rs2952156 1.000 rs1565923 chr17:37858678 A/G cg19468946 chr17:37922297 IKZF3 -0.21 -4.76 -0.39 5.26e-6 Asthma; TGCT cis rs9811920 0.809 rs6440967 chr3:99722396 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.46 -5.18 -0.42 8.59e-7 Axial length; TGCT cis rs9682041 0.696 rs13067560 chr3:170094190 G/A cg11886554 chr3:170076028 SKIL 0.61 4.78 0.39 4.77e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs12541335 0.639 rs11779277 chr8:22200683 C/T cg02788857 chr8:22132959 PIWIL2 0.28 5.15 0.42 9.82e-7 Hypertriglyceridemia; TGCT cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT trans rs8073060 0.544 rs1080352 chr17:34002362 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs3784262 0.669 rs2414527 chr15:58256672 A/G cg12031962 chr15:58353849 ALDH1A2 0.42 6.17 0.48 8.88e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6964587 1.000 rs2282974 chr7:91761617 G/A cg22709100 chr7:91322751 NA 0.29 4.7 0.39 6.9e-6 Breast cancer; TGCT cis rs7474896 0.609 rs1830612 chr10:37999883 A/G cg25427524 chr10:38739819 LOC399744 -0.31 -4.89 -0.4 3.01e-6 Obesity (extreme); TGCT cis rs2836974 0.897 rs2776308 chr21:40715175 A/G cg06238570 chr21:40685208 BRWD1 0.67 5.84 0.46 4.4e-8 Cognitive function; TGCT cis rs28595532 0.920 rs114414928 chr4:119728188 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Mean corpuscular hemoglobin; TGCT trans rs797680 0.964 rs797668 chr1:93694789 C/G cg27528825 chr2:159282178 CCDC148 0.34 6.7 0.52 6.63e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs763121 0.853 rs6519120 chr22:38991393 A/C cg06022373 chr22:39101656 GTPBP1 -0.78 -7.44 -0.56 1.48e-11 Menopause (age at onset); TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg20007245 chr22:24372913 LOC391322 -0.74 -7.41 -0.55 1.71e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17221829 0.733 rs10765227 chr11:89385116 A/G cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs1044826 0.619 rs6439856 chr3:139134868 A/T cg00490450 chr3:139108681 COPB2 -0.53 -4.56 -0.38 1.2e-5 Obesity-related traits; TGCT cis rs2120019 0.786 rs12911421 chr15:75287822 C/A cg09165964 chr15:75287851 SCAMP5 1.19 12.85 0.76 1.48e-24 Blood trace element (Zn levels); TGCT cis rs1552244 0.554 rs2272118 chr3:10049287 T/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs8062405 0.824 rs4788084 chr16:28539848 C/T cg09754948 chr16:28834200 ATXN2L 0.58 4.57 0.38 1.14e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6087771 0.682 rs2038397 chr20:30217759 A/G cg10886678 chr20:30946050 ASXL1 -0.58 -4.64 -0.38 8.56e-6 Subcortical brain region volumes;Putamen volume; TGCT cis rs4087296 0.585 rs11865194 chr16:82381290 G/T cg05453434 chr16:83371223 CDH13 0.33 4.49 0.37 1.61e-5 Bone mineral density; TGCT cis rs55823223 0.503 rs9906971 chr17:73848477 A/G cg08125733 chr17:73851984 WBP2 0.87 8.8 0.62 1e-14 Psoriasis; TGCT cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg04608855 chr19:58913158 NA 0.5 4.74 0.39 5.7e-6 Uric acid clearance; TGCT cis rs9443645 0.901 rs12193319 chr6:79583437 C/A cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.967 rs6456732 chr6:26514445 T/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs637571 0.512 rs660118 chr11:65735174 G/C cg17985854 chr11:65770987 BANF1;EIF1AD 0.21 4.49 0.37 1.61e-5 Eosinophil percentage of white cells; TGCT cis rs9549367 0.713 rs9577211 chr13:113830718 G/C cg18105134 chr13:113819100 PROZ -0.47 -8.52 -0.61 4.48e-14 Platelet distribution width; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg21672276 chr3:44754072 ZNF502 -0.53 -6.23 -0.49 6.64e-9 Depressive symptoms; TGCT cis rs7926906 0.967 rs2213086 chr11:90528578 A/T cg26138821 chr11:89956704 CHORDC1 -0.52 -5.61 -0.45 1.24e-7 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg20276088 chr3:133502917 NA -0.27 -5.59 -0.45 1.38e-7 Iron status biomarkers; TGCT cis rs514406 0.505 rs440871 chr1:53173052 C/T cg08859206 chr1:53392774 SCP2 -0.34 -4.92 -0.4 2.69e-6 Monocyte count; TGCT cis rs548181 0.736 rs556884 chr11:125550049 G/A cg03464685 chr11:125439445 EI24 1.41 10.08 0.67 7.91e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10089 1.000 rs4836366 chr5:127482494 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.64e-13 Ileal carcinoids; TGCT cis rs988712 0.705 rs10767654 chr11:27640223 T/G cg10635145 chr11:27742435 BDNF 0.36 4.88 0.4 3.18e-6 Obesity; TGCT cis rs6940638 0.688 rs9393795 chr6:27217719 G/C cg05738196 chr6:26577821 NA -0.55 -5.01 -0.41 1.82e-6 Intelligence (multi-trait analysis); TGCT cis rs12908161 1.000 rs12899981 chr15:85302373 G/A cg12863693 chr15:85201151 NMB 0.43 5.06 0.41 1.46e-6 Schizophrenia; TGCT cis rs61990749 0.597 rs6574391 chr14:78208121 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs10114408 0.959 rs10761303 chr9:96656918 T/G cg13679303 chr9:96623674 NA -0.36 -4.67 -0.39 7.67e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6964587 1.000 rs58965837 chr7:91585258 T/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs6450176 0.625 rs11747281 chr5:53289047 G/A ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.58 -0.45 1.45e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7726839 0.540 rs3762951 chr5:662613 C/G cg09021430 chr5:549028 NA -0.41 -5.77 -0.46 6.04e-8 Obesity-related traits; TGCT cis rs11190604 1.000 rs2295774 chr10:102265847 A/C cg23241863 chr10:102295624 HIF1AN 0.66 4.86 0.4 3.55e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.753 rs13111199 chr4:98953705 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 1.000 rs7617989 chr3:40512463 A/G cg17264618 chr3:40429014 ENTPD3 -0.33 -4.8 -0.4 4.51e-6 Renal cell carcinoma; TGCT cis rs595982 0.517 rs4801779 chr19:49406651 T/G cg21252483 chr19:49399788 TULP2 -0.3 -5.24 -0.43 6.61e-7 Red cell distribution width; TGCT cis rs2997447 0.739 rs72884784 chr1:26432246 G/A cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT cis rs8177253 0.931 rs8177256 chr3:133480276 G/T cg20276088 chr3:133502917 NA -0.24 -5.06 -0.41 1.5e-6 Iron status biomarkers; TGCT cis rs459571 0.883 rs2520096 chr9:136919416 A/G cg14405625 chr9:136855902 VAV2 -0.31 -4.6 -0.38 1.04e-5 Platelet distribution width; TGCT cis rs1568889 1.000 rs35343234 chr11:28034379 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.87 8.23 0.59 2.14e-13 Bipolar disorder; TGCT cis rs6912958 1.000 rs9294379 chr6:88152535 C/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.22 -0.49 7.06e-9 Monocyte percentage of white cells; TGCT trans rs916888 0.773 rs199448 chr17:44809001 A/G cg01341218 chr17:43662625 NA 1.08 9.08 0.63 2.13e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9467711 0.559 rs9393727 chr6:26500011 C/G cg16898833 chr6:26189333 HIST1H4D 1.01 5.1 0.42 1.21e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs60843830 1.000 rs60149603 chr2:285421 A/G cg00108164 chr2:264199 ACP1;SH3YL1 0.7 6.48 0.5 1.97e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs514406 0.861 rs4926576 chr1:53226775 C/T cg25767906 chr1:53392781 SCP2 0.48 5.56 0.45 1.57e-7 Monocyte count; TGCT cis rs6570726 1.000 rs373778 chr6:145873252 C/T cg23711669 chr6:146136114 FBXO30 0.71 6.66 0.51 7.78e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6121246 0.567 rs6058197 chr20:30194899 A/G cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs12776158 0.901 rs59145567 chr10:71217065 G/T cg12610070 chr10:71211762 TSPAN15 -0.59 -5.17 -0.42 9.16e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9653442 0.593 rs10865036 chr2:100860595 A/G cg07810366 chr2:100720526 AFF3 -0.41 -6.26 -0.49 5.76e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4321325 0.546 rs11886766 chr2:127948621 G/A cg09760422 chr2:128146352 NA 0.42 4.52 0.38 1.43e-5 Protein C levels; TGCT cis rs1568889 1.000 rs61889026 chr11:28274803 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.06 0.59 5.42e-13 Bipolar disorder; TGCT cis rs68170813 0.559 rs17429118 chr7:106964052 C/T cg02696742 chr7:106810147 HBP1 -0.71 -5.89 -0.47 3.42e-8 Coronary artery disease; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs9291683 0.585 rs12648479 chr4:10104571 G/A cg11266682 chr4:10021025 SLC2A9 -0.48 -5.65 -0.45 1.03e-7 Bone mineral density; TGCT cis rs769267 1.000 rs2301669 chr19:19453560 C/A cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs9796 0.870 rs2925342 chr15:41305733 A/G cg18705301 chr15:41695430 NDUFAF1 0.41 5.31 0.43 4.93e-7 Menopause (age at onset); TGCT cis rs11098499 1.000 rs10029750 chr4:120172543 A/G cg24670566 chr4:120433619 PDE5A 0.23 4.58 0.38 1.11e-5 Corneal astigmatism; TGCT cis rs732765 0.734 rs10142036 chr14:75126992 T/A cg06637938 chr14:75390232 RPS6KL1 -0.57 -4.95 -0.41 2.4e-6 Non-small cell lung cancer; TGCT cis rs2836974 0.644 rs11088471 chr21:40699313 A/G cg11890956 chr21:40555474 PSMG1 -0.72 -6.49 -0.5 1.87e-9 Cognitive function; TGCT cis rs4253772 0.550 rs6008600 chr22:46704676 A/G cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs57920188 0.640 rs4478781 chr1:4086827 C/T cg20703997 chr1:4087676 NA 0.45 4.71 0.39 6.56e-6 Interleukin-17 levels; TGCT cis rs75229567 0.618 rs11177853 chr12:70184924 A/G cg10114359 chr12:70132523 RAB3IP 1.35 6.68 0.51 7.19e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT trans rs561341 0.602 rs114562703 chr17:30233899 G/T cg20587970 chr11:113659929 NA -0.68 -9.46 -0.65 2.55e-16 Hip circumference adjusted for BMI; TGCT cis rs2580764 0.566 rs2920900 chr2:55280083 T/C cg09592903 chr2:55203963 RTN4 0.25 5.92 0.47 2.96e-8 Mean platelet volume; TGCT cis rs600550 0.926 rs633463 chr11:60005173 T/G cg18570331 chr11:60101691 MS4A6E 0.5 4.49 0.37 1.63e-5 Lipoprotein-associated phospholipase A2 activity and mass; TGCT cis rs514406 0.505 rs431427 chr1:53179094 C/A cg08859206 chr1:53392774 SCP2 -0.36 -5.23 -0.42 7.05e-7 Monocyte count; TGCT cis rs3743266 0.507 rs11637887 chr15:60765216 C/T cg18480781 chr15:60294291 NA 0.63 4.94 0.41 2.46e-6 Menarche (age at onset); TGCT trans rs9951602 0.512 rs4799248 chr18:76653459 G/A cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs7264396 0.790 rs6058290 chr20:34247702 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.68 -0.39 7.38e-6 Total cholesterol levels; TGCT cis rs8077577 0.945 rs9916193 chr17:18057215 C/G cg09161412 chr17:18057145 MYO15A -0.64 -5.3 -0.43 5.21e-7 Obesity-related traits; TGCT cis rs2439831 0.717 rs2470132 chr15:43835481 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.79 0.46 5.33e-8 Lung cancer in ever smokers; TGCT cis rs765787 0.530 rs10467979 chr15:45521270 G/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.45 -0.44 2.66e-7 Uric acid levels; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg05064044 chr6:292385 DUSP22 -0.7 -7.14 -0.54 6.88e-11 Menopause (age at onset); TGCT cis rs7666738 0.546 rs7679681 chr4:98882221 A/G cg05340658 chr4:99064831 C4orf37 0.58 6.09 0.48 1.28e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs17685 0.753 rs1806885 chr7:75785612 T/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2204008 0.577 rs2623049 chr12:38018831 G/A cg26384229 chr12:38710491 ALG10B -0.7 -6.13 -0.48 1.1e-8 Bladder cancer; TGCT cis rs1008375 0.931 rs2098151 chr4:17577490 T/C cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs425277 0.583 rs4648807 chr1:2040898 A/G cg03732007 chr1:2071316 PRKCZ -0.27 -5.96 -0.47 2.39e-8 Height; TGCT trans rs6089829 0.962 rs6089825 chr20:61668447 C/T cg17470723 chr8:74884337 TCEB1 0.76 7.34 0.55 2.42e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.14e-6 Blood metabolite levels; TGCT cis rs769267 0.825 rs1469713 chr19:19528806 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.25 0.43 6.3e-7 Tonsillectomy; TGCT cis rs7267979 1.000 rs4813562 chr20:25352588 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs61990749 0.597 rs2032781 chr14:78214875 A/G cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs1218582 0.774 rs4845681 chr1:154868055 G/T cg06221963 chr1:154839813 KCNN3 -0.81 -15.28 -0.81 2.67e-30 Prostate cancer; TGCT cis rs4780401 0.609 rs35902600 chr16:11800848 C/T cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs2458413 0.669 rs1812214 chr8:105344070 A/G cg04554929 chr8:105342491 NA -0.59 -9.16 -0.64 1.34e-15 Paget's disease; TGCT cis rs78487399 0.808 rs6717636 chr2:43703684 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7412746 0.621 rs11204749 chr1:150929563 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs7666738 0.830 rs7674095 chr4:99048158 T/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs5769765 0.908 rs138889 chr22:50226673 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.59 0.45 1.36e-7 Schizophrenia; TGCT cis rs4824093 0.610 rs60036544 chr22:50264019 C/T cg14114931 chr22:50943910 LMF2 0.37 4.58 0.38 1.11e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7043114 0.525 rs2274966 chr9:95155563 C/A cg14631576 chr9:95140430 CENPP -0.27 -4.56 -0.38 1.22e-5 Height; TGCT cis rs1577917 0.958 rs4707223 chr6:86509802 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.7 -5.77 -0.46 6.01e-8 Response to antipsychotic treatment; TGCT cis rs1023500 0.551 rs2301521 chr22:42423110 G/C cg05082376 chr22:42548792 NA -0.22 -5.27 -0.43 5.83e-7 Schizophrenia; TGCT cis rs71597109 0.594 rs13131198 chr4:102730555 A/G cg14855874 chr4:102712397 BANK1 0.42 4.59 0.38 1.09e-5 Chronic lymphocytic leukemia; TGCT cis rs2439831 1.000 rs690263 chr15:43704465 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.12 0.59 3.99e-13 Lung cancer in ever smokers; TGCT cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs597539 0.616 rs513476 chr11:68698996 C/T cg21963583 chr11:68658836 MRPL21 0.35 5.8 0.46 5.09e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs116095464 0.619 rs2303741 chr5:218356 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs8177253 0.965 rs8177260 chr3:133480458 T/A cg01448562 chr3:133502909 NA -0.34 -6.76 -0.52 4.81e-10 Iron status biomarkers; TGCT cis rs763014 1.000 rs8054842 chr16:672799 T/C cg00908189 chr16:619842 PIGQ 0.88 10.66 0.69 3.21e-19 Height; TGCT cis rs9906944 0.713 rs9899580 chr17:47106878 T/G cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT trans rs17685 0.712 rs6976236 chr7:75741087 G/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7954584 0.567 rs7132055 chr12:122346034 A/G cg22618164 chr12:122356400 WDR66 -0.66 -6.18 -0.48 8.67e-9 Mean corpuscular volume; TGCT cis rs172166 0.694 rs203876 chr6:28046673 T/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.79 0.39 4.75e-6 Cardiac Troponin-T levels; TGCT cis rs1461503 0.966 rs11218908 chr11:122841687 A/G cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs6138458 1.000 rs11906373 chr20:24938832 A/G cg26195577 chr20:24973756 C20orf3 1.18 11.12 0.71 2.37e-20 Blood protein levels; TGCT cis rs929354 0.742 rs10251112 chr7:156963524 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.77 -0.62 1.19e-14 Body mass index; TGCT cis rs7666738 0.716 rs6817529 chr4:99023213 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.931 rs2989330 chr21:40716209 A/G cg11890956 chr21:40555474 PSMG1 0.95 8.05 0.59 5.73e-13 Cognitive function; TGCT cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg08392591 chr16:89556376 ANKRD11 0.6 5.64 0.45 1.09e-7 Multiple myeloma (IgH translocation); TGCT cis rs10193935 0.901 rs3088290 chr2:42578143 A/G cg27598129 chr2:42591480 NA -0.41 -5.66 -0.45 1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs9522267 0.535 rs914036 chr13:112235542 G/A cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs9913156 0.589 rs7213481 chr17:4547906 C/T cg19197139 chr17:4613644 ARRB2 0.85 7.84 0.58 1.76e-12 Lymphocyte counts; TGCT cis rs17376456 1.000 rs35184505 chr5:93561535 A/G cg25358565 chr5:93447407 FAM172A 0.95 7.18 0.54 5.63e-11 Diabetic retinopathy; TGCT cis rs3008870 1.000 rs12117131 chr1:67451922 C/T cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg06634786 chr22:41940651 POLR3H -0.84 -7.83 -0.57 1.91e-12 Vitiligo; TGCT cis rs986417 1.000 rs1254287 chr14:60861774 C/T cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs9581857 0.512 rs9581866 chr13:28063176 G/A cg22138327 chr13:27999177 GTF3A 0.73 4.55 0.38 1.25e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2486012 1.000 rs1859725 chr1:44379577 A/G cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.564 rs56054309 chr2:100794940 T/C cg22139774 chr2:100720529 AFF3 -0.32 -4.98 -0.41 2.06e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs477895 0.652 rs72920332 chr11:63947071 G/T cg23719950 chr11:63933701 MACROD1 -0.72 -5.95 -0.47 2.61e-8 Mean platelet volume; TGCT cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs2594989 0.943 rs2454512 chr3:11487506 A/G cg26283222 chr3:11613257 VGLL4 -0.21 -4.46 -0.37 1.84e-5 Circulating chemerin levels; TGCT cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg09177884 chr7:1199841 ZFAND2A -0.53 -5.06 -0.41 1.47e-6 Longevity;Endometriosis; TGCT cis rs6714710 0.603 rs717417 chr2:98416850 T/G cg26665480 chr2:98280029 ACTR1B 0.7 6.61 0.51 1.05e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7552404 0.765 rs1251078 chr1:76189488 C/G cg03433033 chr1:76189801 ACADM -0.9 -13.97 -0.78 3.22e-27 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1218582 0.772 rs12069356 chr1:154849771 C/T cg03351412 chr1:154909251 PMVK 0.49 4.58 0.38 1.13e-5 Prostate cancer; TGCT trans rs1814175 0.817 rs28679516 chr11:50055998 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs9733 0.818 rs4970926 chr1:150673684 T/C cg13175981 chr1:150552382 MCL1 0.43 4.78 0.39 4.77e-6 Tonsillectomy; TGCT cis rs2245008 0.671 rs907036 chr16:83989850 A/T cg07978099 chr16:83986941 OSGIN1 0.4 5.03 0.41 1.68e-6 Pursuit maintenance gain; TGCT cis rs2439831 0.867 rs12323999 chr15:43683115 T/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.14 0.59 3.58e-13 Lung cancer in ever smokers; TGCT cis rs733175 0.855 rs10018666 chr4:10004805 C/T cg11266682 chr4:10021025 SLC2A9 0.47 4.63 0.38 9.05e-6 Psychosis and Alzheimer's disease; TGCT cis rs17125944 0.505 rs74642116 chr14:53213507 A/G cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs2933343 0.761 rs789225 chr3:128600229 G/A cg11901034 chr3:128598214 ACAD9 -0.64 -6.11 -0.48 1.16e-8 IgG glycosylation; TGCT cis rs12200560 0.505 rs211175 chr6:97073320 C/T cg06623918 chr6:96969491 KIAA0776 0.62 5.37 0.43 3.66e-7 Coronary heart disease; TGCT cis rs1723838 0.826 rs9651759 chr11:73602950 G/A cg18195628 chr11:73498948 MRPL48 0.92 4.5 0.38 1.51e-5 Obesity-related traits; TGCT cis rs12477438 0.798 rs6716913 chr2:99580641 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs72781680 0.898 rs72788214 chr2:24087621 A/C cg08917208 chr2:24149416 ATAD2B 0.77 4.69 0.39 7.06e-6 Lymphocyte counts; TGCT cis rs9976767 0.637 rs2277799 chr21:43824123 G/C cg23042151 chr21:43824109 UBASH3A -0.22 -4.81 -0.4 4.32e-6 Type 1 diabetes; TGCT cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg06634786 chr22:41940651 POLR3H -0.85 -8.19 -0.59 2.72e-13 Vitiligo; TGCT cis rs10479542 0.766 rs6894980 chr5:178974592 C/T cg09060608 chr5:178986726 RUFY1 0.48 5.46 0.44 2.49e-7 Lung cancer; TGCT cis rs742614 0.935 rs6057929 chr20:32477633 A/G cg18223379 chr20:31619647 BPIL3 -0.18 -4.48 -0.37 1.71e-5 Stearic acid (18:0) levels; TGCT cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg17554472 chr22:41940697 POLR3H 0.47 5.04 0.41 1.63e-6 Vitiligo; TGCT cis rs11119608 0.960 rs11119609 chr1:210995866 A/G cg24524366 chr1:211689016 NA 0.52 4.72 0.39 6.27e-6 Cancer; TGCT cis rs13256369 0.901 rs12679831 chr8:8566411 T/G cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs9926296 0.572 rs8046872 chr16:89841552 T/C cg04287289 chr16:89883240 FANCA 0.66 6.54 0.51 1.42e-9 Vitiligo; TGCT cis rs459571 0.883 rs2520096 chr9:136919416 A/G cg13789015 chr9:136890014 NCRNA00094 0.37 6.37 0.5 3.34e-9 Platelet distribution width; TGCT cis rs4499344 0.693 rs8106944 chr19:33097783 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.7 0.62 1.68e-14 Mean platelet volume; TGCT cis rs875971 0.862 rs3926380 chr7:66080645 G/T cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.89e-6 Aortic root size; TGCT cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs11031096 0.711 rs4910891 chr11:4153408 A/G cg18678763 chr11:4115507 RRM1 -0.52 -6.66 -0.51 7.83e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg17264618 chr3:40429014 ENTPD3 -0.33 -4.69 -0.39 7.17e-6 Renal cell carcinoma; TGCT cis rs7937682 0.924 rs489783 chr11:111520522 A/G cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs9913156 0.793 rs11568061 chr17:4546445 G/A cg00122941 chr17:4613640 ARRB2 0.87 7.41 0.55 1.69e-11 Lymphocyte counts; TGCT cis rs6938 0.563 rs12917376 chr15:75116167 C/T cg10253484 chr15:75165896 SCAMP2 -0.55 -4.83 -0.4 3.91e-6 Breast cancer; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg15383120 chr6:291909 DUSP22 -0.7 -7.19 -0.54 5.32e-11 Menopause (age at onset); TGCT cis rs10501293 0.917 rs9645617 chr11:43105620 G/A cg03447554 chr11:43094025 NA -0.47 -6.58 -0.51 1.2e-9 Cognitive performance; TGCT cis rs13118159 0.778 rs12640984 chr4:1338834 G/A cg13395646 chr4:1353034 KIAA1530 -0.41 -5.02 -0.41 1.76e-6 Longevity; TGCT cis rs7940866 1.000 rs7940866 chr11:130817579 A/T cg05962950 chr11:130786565 SNX19 -0.74 -7.35 -0.55 2.33e-11 Schizophrenia; TGCT cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg17747265 chr1:1875780 NA -0.44 -8.44 -0.6 6.93e-14 Body mass index; TGCT cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs7714584 1.000 rs80075680 chr5:150223737 C/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs9837602 0.507 rs793455 chr3:99526135 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.91 0.53 2.27e-10 Breast cancer; TGCT cis rs928736 0.599 rs1000005 chr21:34433051 C/G cg00274965 chr21:34405681 NA 0.55 6.36 0.5 3.58e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs6683273 0.830 rs3192920 chr1:3229385 T/G cg17435683 chr1:3230609 PRDM16 -0.4 -4.53 -0.38 1.35e-5 QRS duration; TGCT cis rs4455778 0.659 rs61486133 chr7:49027781 T/C cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs174479 0.647 rs174461 chr11:61657401 A/C cg19610905 chr11:61596333 FADS2 0.58 5.05 0.41 1.56e-6 Sphingolipid levels; TGCT cis rs7707921 0.752 rs12108681 chr5:81278375 T/C cg17933386 chr5:81047246 SSBP2 0.57 4.45 0.37 1.88e-5 Breast cancer; TGCT cis rs4319547 0.698 rs4039670 chr12:122822655 A/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.68 -0.39 7.27e-6 Body mass index; TGCT cis rs12497850 0.931 rs9755490 chr3:48871664 A/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs708547 0.836 rs1718882 chr4:57859533 C/G cg25525207 chr4:57843836 C4orf14;POLR2B -0.53 -4.92 -0.4 2.7e-6 Response to bleomycin (chromatid breaks); TGCT cis rs13108904 0.846 rs4974574 chr4:1224811 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.9 0.4 2.98e-6 Obesity-related traits; TGCT cis rs9913156 0.793 rs4346260 chr17:4567215 A/G cg00122941 chr17:4613640 ARRB2 -0.89 -7.56 -0.56 7.65e-12 Lymphocyte counts; TGCT cis rs67311347 0.544 rs9864601 chr3:40345318 C/T cg13683864 chr3:40499215 RPL14 -0.79 -7.57 -0.56 7.26e-12 Renal cell carcinoma; TGCT cis rs7819412 0.775 rs6601564 chr8:10982051 A/G cg21775007 chr8:11205619 TDH -0.54 -5.21 -0.42 7.67e-7 Triglycerides; TGCT cis rs2486288 0.656 rs11629807 chr15:45547037 T/C cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs826838 1.000 rs4575342 chr12:38663831 G/A cg13010199 chr12:38710504 ALG10B 0.77 6.31 0.49 4.59e-9 Heart rate; TGCT cis rs6088590 1.000 rs6119530 chr20:33403930 A/G cg06115741 chr20:33292138 TP53INP2 0.65 5.45 0.44 2.66e-7 Coronary artery disease; TGCT cis rs7582180 0.629 rs13031906 chr2:100939524 T/C cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs9381040 0.655 rs2268187 chr6:41042993 G/A cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs2836974 0.897 rs13052882 chr21:40555351 G/C cg06238570 chr21:40685208 BRWD1 0.76 7.01 0.53 1.37e-10 Cognitive function; TGCT cis rs6940638 0.688 rs6456766 chr6:27019575 G/A cg26531700 chr6:26746687 NA -0.56 -5.04 -0.41 1.61e-6 Intelligence (multi-trait analysis); TGCT cis rs4822044 0.568 rs1883370 chr22:42143740 C/A cg17554472 chr22:41940697 POLR3H 0.46 4.76 0.39 5.4e-6 Cannabis dependence symptom count; TGCT cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg03609598 chr5:56110824 MAP3K1 -0.57 -4.5 -0.37 1.57e-5 Initial pursuit acceleration; TGCT cis rs6815814 0.950 rs5743595 chr4:38802644 A/G cg02016764 chr4:38805732 TLR1 -0.35 -5.82 -0.46 4.68e-8 Breast cancer; TGCT cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg13866156 chr1:1669148 SLC35E2 0.23 5.66 0.45 9.78e-8 Body mass index; TGCT cis rs477895 1.000 rs7947143 chr11:64090422 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.19 0.42 8.41e-7 Mean platelet volume; TGCT cis rs7909074 0.865 rs10900123 chr10:45376574 C/T cg04218760 chr10:45406644 TMEM72 -0.3 -5.92 -0.47 2.88e-8 Mean corpuscular volume; TGCT cis rs1395 1.000 rs1275538 chr2:27441397 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.54 7.36 0.55 2.23e-11 Blood metabolite levels; TGCT cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 6.87 0.52 2.82e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg17554472 chr22:41940697 POLR3H -0.5 -5.2 -0.42 8.14e-7 Vitiligo; TGCT cis rs950169 0.580 rs17532346 chr15:85171495 A/C cg12863693 chr15:85201151 NMB 0.44 5.2 0.42 7.82e-7 Schizophrenia; TGCT cis rs4888262 0.545 rs36097721 chr16:74648267 C/G cg01733217 chr16:74700730 RFWD3 0.74 7.47 0.56 1.23e-11 Testicular germ cell tumor; TGCT cis rs7223966 1.000 rs2854223 chr17:61939014 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 5.17 0.42 9.21e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9297145 0.565 rs12705030 chr7:98765041 A/G cg05967295 chr7:98741636 SMURF1 -0.68 -8.69 -0.62 1.83e-14 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs2836974 0.897 rs35123057 chr21:40711689 C/T cg11890956 chr21:40555474 PSMG1 1.02 9.9 0.66 2.16e-17 Cognitive function; TGCT cis rs6714710 0.603 rs11678591 chr2:98541001 T/C cg26665480 chr2:98280029 ACTR1B 0.63 5.98 0.47 2.19e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs9303401 0.538 rs2240258 chr17:56458183 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.75 6.8 0.52 3.94e-10 Cognitive test performance; TGCT cis rs7267979 1.000 rs2259837 chr20:25280205 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.753 rs10004827 chr4:99037953 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.83 0.46 4.41e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10986311 0.832 rs7875898 chr9:127140523 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -4.89 -0.4 3.02e-6 Vitiligo; TGCT cis rs6912958 0.559 rs395358 chr6:88057924 T/C cg08069147 chr6:88032118 GJB7;C6orf162 0.68 6.88 0.53 2.68e-10 Monocyte percentage of white cells; TGCT cis rs7666738 0.581 rs34205844 chr4:98887494 C/A cg05340658 chr4:99064831 C4orf37 0.5 5.58 0.45 1.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2486288 0.656 rs2271438 chr15:45557468 A/G cg26924012 chr15:45694286 SPATA5L1 -0.75 -7.78 -0.57 2.39e-12 Glomerular filtration rate; TGCT cis rs68170813 0.652 rs75136686 chr7:107180949 G/A cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs13256369 1.000 rs883648 chr8:8569521 A/G cg17143192 chr8:8559678 CLDN23 0.58 5.56 0.45 1.56e-7 Obesity-related traits; TGCT cis rs72781680 0.706 rs72794290 chr2:23896106 A/T cg08917208 chr2:24149416 ATAD2B 1.01 5.58 0.45 1.45e-7 Lymphocyte counts; TGCT cis rs10876993 0.826 rs1678534 chr12:58057435 A/C cg15848620 chr12:58087721 OS9 -0.73 -5.94 -0.47 2.74e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs10464366 0.560 rs12701692 chr7:39135551 A/G cg18850127 chr7:39170497 POU6F2 0.25 5.76 0.46 6.29e-8 IgG glycosylation; TGCT cis rs7819412 0.678 rs11991716 chr8:10948575 A/T cg21775007 chr8:11205619 TDH -0.51 -4.58 -0.38 1.1e-5 Triglycerides; TGCT cis rs13102973 0.835 rs4280795 chr4:135857246 T/A cg14419869 chr4:135874104 NA 0.23 4.58 0.38 1.12e-5 Subjective well-being; TGCT cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg14827481 chr10:134361889 INPP5A 0.28 4.51 0.38 1.5e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs514406 0.861 rs11206026 chr1:53281708 G/A cg16325326 chr1:53192061 ZYG11B 0.7 8.71 0.62 1.59e-14 Monocyte count; TGCT cis rs9902453 0.967 rs56129908 chr17:28421382 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.52 0.51 1.63e-9 Coffee consumption (cups per day); TGCT cis rs2932538 0.885 rs7516421 chr1:113089696 T/C cg22162597 chr1:113214053 CAPZA1 0.25 5.5 0.44 2.06e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs4688759 0.719 rs73079018 chr3:49875327 T/C cg00383909 chr3:49044727 WDR6 1.31 6.62 0.51 9.53e-10 Blood protein levels; TGCT cis rs614226 1.000 rs580016 chr12:120933977 T/C cg10072921 chr12:121022843 NA 0.45 4.85 0.4 3.68e-6 Type 1 diabetes nephropathy; TGCT cis rs12478296 1.000 rs113129906 chr2:243004253 C/T cg06360820 chr2:242988706 NA -0.85 -5.6 -0.45 1.32e-7 Obesity-related traits; TGCT cis rs9303401 0.659 rs17741087 chr17:56550300 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.77 0.52 4.6e-10 Cognitive test performance; TGCT cis rs1843834 0.539 rs2047135 chr2:225427302 G/C cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs3784262 1.000 rs3204689 chr15:58246802 G/C cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.6 -0.56 6.19e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs929596 0.755 rs6742078 chr2:234672639 A/C cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 0.34 5.62 0.45 1.22e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs7267979 1.000 rs2259928 chr20:25281834 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4918072 0.667 rs4439443 chr10:105704814 G/T cg11005552 chr10:105648138 OBFC1 0.34 4.8 0.4 4.53e-6 Coronary artery disease; TGCT cis rs3858526 0.606 rs10838883 chr11:5952147 G/A cg02574844 chr11:5959923 NA 0.44 4.91 0.4 2.85e-6 DNA methylation (variation); TGCT cis rs3772130 0.962 rs11721291 chr3:121563285 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs7674212 0.541 rs2615539 chr4:104081106 C/G cg16532752 chr4:104119610 CENPE -0.61 -5.67 -0.45 9.45e-8 Type 2 diabetes; TGCT cis rs11105298 1.000 rs11105298 chr12:89876143 C/T cg00757033 chr12:89920650 WDR51B -0.32 -5.12 -0.42 1.16e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs208520 0.690 rs12208310 chr6:66730108 G/C cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs2242116 0.761 rs6780601 chr3:46965856 A/G cg27129171 chr3:47204927 SETD2 0.66 6.34 0.49 3.88e-9 Birth weight; TGCT cis rs12142240 0.698 rs67142569 chr1:46828460 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs4566357 1.000 rs2177598 chr2:227922900 T/C cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs9486715 0.867 rs9386500 chr6:96889845 A/C cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs9611565 0.649 rs9623450 chr22:42175231 G/A cg17554472 chr22:41940697 POLR3H 0.43 4.61 0.38 9.67e-6 Vitiligo; TGCT cis rs6969780 0.630 rs10238095 chr7:27196643 A/G cg04321618 chr7:27170880 HOXA4 -0.54 -5.21 -0.42 7.8e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT trans rs10022799 0.725 rs9996196 chr4:168136671 G/A cg08507725 chr4:8239220 SH3TC1 0.42 7.37 0.55 2.15e-11 Cognitive function; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg08859206 chr1:53392774 SCP2 -0.41 -6.12 -0.48 1.11e-8 Monocyte count; TGCT cis rs4727027 0.716 rs4727020 chr7:148837317 C/T cg23583168 chr7:148888333 NA -0.66 -7.38 -0.55 2e-11 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7100689 0.577 rs10749551 chr10:82054001 A/C cg01528321 chr10:82214614 TSPAN14 0.7 6.78 0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs986417 0.901 rs1024224 chr14:60926942 C/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs10782582 0.522 rs12125933 chr1:76130920 C/T cg10523679 chr1:76189770 ACADM -0.68 -7.1 -0.54 8.65e-11 Daytime sleep phenotypes; TGCT cis rs854765 0.624 rs12946746 chr17:17741669 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.67 -0.51 7.5e-10 Total body bone mineral density; TGCT cis rs546131 0.642 rs2956073 chr11:34842883 C/T cg06937548 chr11:34938143 PDHX;APIP 0.54 4.67 0.39 7.64e-6 Lung disease severity in cystic fibrosis; TGCT cis rs10504229 0.871 rs60342323 chr8:58154899 T/C cg21724239 chr8:58056113 NA 0.4 5.15 0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs10501293 0.746 rs7105687 chr11:43035922 C/T cg03447554 chr11:43094025 NA 0.44 6.29 0.49 5.05e-9 Cognitive performance; TGCT cis rs11792861 0.926 rs75472294 chr9:111804239 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.47 4.44 0.37 1.98e-5 Menarche (age at onset); TGCT cis rs2404602 0.716 rs1125932 chr15:76820540 C/T cg22467129 chr15:76604101 ETFA -0.48 -5.53 -0.44 1.81e-7 Blood metabolite levels; TGCT cis rs2204008 0.728 rs12369538 chr12:38443942 C/T cg13010199 chr12:38710504 ALG10B 0.56 4.44 0.37 2e-5 Bladder cancer; TGCT cis rs2797160 1.000 rs1739349 chr6:126014984 G/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs1348850 0.914 rs10497503 chr2:178371739 G/T cg22681709 chr2:178499509 PDE11A -0.34 -4.58 -0.38 1.11e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs977747 0.933 rs2008713 chr1:47702368 T/C cg03885399 chr1:47691550 TAL1 -0.37 -4.46 -0.37 1.8e-5 Body mass index; TGCT cis rs4972806 0.739 rs10834 chr2:177042087 A/G cg14324370 chr2:177042789 NA 0.63 5.24 0.43 6.71e-7 IgG glycosylation; TGCT cis rs1475911 0.671 rs12483409 chr21:43521902 G/A cg24372256 chr21:43528868 UMODL1;C21orf128 -0.31 -5.88 -0.47 3.64e-8 IgG glycosylation; TGCT cis rs4713118 0.587 rs61471148 chr6:28037032 T/A cg12963246 chr6:28129442 ZNF389 0.48 4.65 0.39 8.28e-6 Parkinson's disease; TGCT cis rs763121 1.000 rs138457 chr22:38898051 T/C cg06022373 chr22:39101656 GTPBP1 -0.71 -7.06 -0.54 1.07e-10 Menopause (age at onset); TGCT cis rs13242816 1.000 rs2191498 chr7:116138569 C/T cg16553024 chr7:116138462 CAV2 -0.44 -5.34 -0.43 4.29e-7 P wave duration; TGCT trans rs9951602 0.512 rs56009939 chr18:76644497 T/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs10782582 0.593 rs4646960 chr1:76211103 C/A cg10523679 chr1:76189770 ACADM -0.67 -6.71 -0.52 6.18e-10 Daytime sleep phenotypes; TGCT cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg20203395 chr5:56204925 C5orf35 -0.57 -4.82 -0.4 4.15e-6 Initial pursuit acceleration; TGCT cis rs6138458 0.546 rs6050118 chr20:24891895 C/T cg26195577 chr20:24973756 C20orf3 -0.87 -4.9 -0.4 2.99e-6 Blood protein levels; TGCT cis rs6490294 0.950 rs7313892 chr12:112421352 G/T cg10833066 chr12:111807467 FAM109A 0.35 5.13 0.42 1.09e-6 Mean platelet volume; TGCT cis rs12765878 1.000 rs10883943 chr10:105651416 G/T cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs13256369 0.802 rs4840350 chr8:8561442 A/G cg17143192 chr8:8559678 CLDN23 0.54 5.03 0.41 1.64e-6 Obesity-related traits; TGCT cis rs9372253 0.678 rs9372251 chr6:110700656 A/G cg01119278 chr6:110721349 DDO -0.31 -4.76 -0.39 5.25e-6 Platelet distribution width; TGCT cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg11279151 chr3:101281821 RG9MTD1 0.34 7.13 0.54 7.37e-11 Colorectal cancer; TGCT cis rs9611565 0.649 rs5758442 chr22:42133060 T/C cg06481639 chr22:41940642 POLR3H 0.54 4.57 0.38 1.17e-5 Vitiligo; TGCT cis rs4144743 1.000 rs72823473 chr17:45321775 A/T cg18085866 chr17:45331354 ITGB3 -0.7 -4.67 -0.39 7.81e-6 Body mass index; TGCT cis rs4819052 0.851 rs2236446 chr21:46678985 T/C cg06618935 chr21:46677482 NA -0.36 -5.5 -0.44 2.06e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs826838 1.000 rs1843881 chr12:38733706 A/G cg26384229 chr12:38710491 ALG10B -1.07 -10.48 -0.69 8.51e-19 Heart rate; TGCT cis rs9549367 0.713 rs576463 chr13:113846614 C/T cg00898013 chr13:113819073 PROZ 0.53 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs2921036 0.545 rs4840975 chr8:8363258 C/T cg06636001 chr8:8085503 FLJ10661 -0.62 -5.48 -0.44 2.31e-7 Neuroticism; TGCT cis rs2486288 0.656 rs1719236 chr15:45577783 G/T cg14582100 chr15:45693742 SPATA5L1 -0.42 -4.85 -0.4 3.61e-6 Glomerular filtration rate; TGCT cis rs67460515 0.926 rs13062740 chr3:161024208 G/A cg03342759 chr3:160939853 NMD3 -0.51 -5.46 -0.44 2.47e-7 Parkinson's disease; TGCT cis rs7095607 0.560 rs2087344 chr10:69922735 A/G cg18986048 chr10:69913749 MYPN -0.53 -5.62 -0.45 1.19e-7 Lung function (FVC); TGCT cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg17054783 chr10:134559939 INPP5A 0.24 4.87 0.4 3.37e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7236492 0.630 rs8086439 chr18:77173038 A/G cg15644404 chr18:77186268 NFATC1 -0.43 -4.44 -0.37 1.96e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs9894429 0.646 rs7405937 chr17:79597811 G/A cg18240062 chr17:79603768 NPLOC4 0.58 5.12 0.42 1.15e-6 Eye color traits; TGCT cis rs11997175 0.549 rs4349945 chr8:33654323 T/C ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs7552404 0.924 rs1146579 chr1:76209792 C/T cg03433033 chr1:76189801 ACADM -0.76 -9.22 -0.64 9.89e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9457247 0.905 rs453184 chr6:167387404 A/C cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs10936602 0.527 rs9878316 chr3:169533717 T/A cg08193579 chr3:169529701 LRRC34 0.29 5.33 0.43 4.38e-7 Renal cell carcinoma; TGCT cis rs2204008 0.837 rs7308714 chr12:38274307 T/C cg13010199 chr12:38710504 ALG10B 0.61 4.67 0.39 7.69e-6 Bladder cancer; TGCT cis rs853679 0.517 rs3757185 chr6:28107776 T/A cg12963246 chr6:28129442 ZNF389 0.52 5.07 0.41 1.42e-6 Depression; TGCT cis rs7582180 0.676 rs11691135 chr2:100934038 C/T cg14675211 chr2:100938903 LONRF2 0.51 4.98 0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs11648796 0.759 rs12597195 chr16:769026 G/C cg00908189 chr16:619842 PIGQ 0.8 6.38 0.5 3.12e-9 Height; TGCT cis rs7220711 0.967 rs4792909 chr17:41798824 G/T cg26893861 chr17:41843967 DUSP3 0.51 4.72 0.39 6.38e-6 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs2229238 0.868 rs41308419 chr1:154507197 T/C cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs9972944 0.702 rs987929 chr17:63765856 A/G cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs8177253 0.965 rs1525889 chr3:133490033 A/C cg08048268 chr3:133502702 NA -0.64 -9.81 -0.66 3.68e-17 Iron status biomarkers; TGCT cis rs35160687 0.871 rs2278105 chr2:86466516 A/G cg04877910 chr2:85804641 VAMP8 0.34 4.47 0.37 1.72e-5 Night sleep phenotypes; TGCT cis rs611744 0.967 rs628843 chr8:109196115 C/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT trans rs17450420 1.000 rs75573069 chr13:105052442 T/C cg14737571 chr13:113436568 ATP11A 0.61 6.63 0.51 9.35e-10 Esophageal cancer (alcohol interaction); TGCT cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg03303774 chr4:1407052 NA 0.34 5.43 0.44 2.91e-7 Obesity-related traits; TGCT cis rs12477438 0.798 rs1349779 chr2:99645055 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.66 -0.61 2.13e-14 Chronic sinus infection; TGCT cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg17554472 chr22:41940697 POLR3H 0.48 5.08 0.42 1.34e-6 Vitiligo; TGCT cis rs2013441 1.000 rs9896709 chr17:20180550 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs597539 0.652 rs544370 chr11:68653232 C/T cg06112835 chr11:68658793 MRPL21 0.46 8.07 0.59 5.25e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3733585 0.699 rs6449178 chr4:9968684 A/G cg11266682 chr4:10021025 SLC2A9 0.57 7.48 0.56 1.19e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg07424592 chr7:64974309 NA -1.33 -7.99 -0.58 7.81e-13 Diabetic kidney disease; TGCT cis rs114540395 0.925 rs12244100 chr10:103379397 T/C cg03300883 chr10:102748874 C10orf2 0.42 4.58 0.38 1.13e-5 Schizophrenia; TGCT cis rs3008870 0.755 rs1121824 chr1:67475616 C/A cg08660285 chr1:67390436 MIER1;WDR78 0.81 8.43 0.6 7.53e-14 Lymphocyte percentage of white cells; TGCT cis rs4972806 0.776 rs2072589 chr2:177042871 C/T cg13092806 chr2:177043255 NA 0.59 5.1 0.42 1.24e-6 IgG glycosylation; TGCT cis rs4253772 0.614 rs11090859 chr22:46687460 T/G cg26492175 chr22:47022658 GRAMD4 0.2 4.52 0.38 1.43e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs2688608 0.592 rs11000759 chr10:75493726 G/A cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs4699052 0.625 rs10212959 chr4:104300935 C/G cg16532752 chr4:104119610 CENPE 0.5 4.65 0.39 8.27e-6 Testicular germ cell tumor; TGCT trans rs4332037 0.851 rs28728306 chr7:1961814 C/A cg25206134 chr2:45395956 NA 1.1 9.53 0.65 1.75e-16 Bipolar disorder; TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs59197085 0.636 rs56377531 chr7:128460745 C/T cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs13326165 0.715 rs13091545 chr3:52377294 A/G cg27565382 chr3:53032988 SFMBT1 0.37 4.93 0.41 2.55e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg00149659 chr3:10157352 C3orf10 0.93 5.98 0.47 2.25e-8 Alzheimer's disease; TGCT cis rs7954584 0.616 rs10743186 chr12:122356436 C/T cg22618164 chr12:122356400 WDR66 0.53 5.18 0.42 8.83e-7 Mean corpuscular volume; TGCT cis rs2204008 0.599 rs2320526 chr12:38220405 T/A cg13010199 chr12:38710504 ALG10B 0.58 4.59 0.38 1.08e-5 Bladder cancer; TGCT cis rs4253772 0.637 rs9627295 chr22:46650100 C/T cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs9787249 0.957 rs56064244 chr1:40213890 C/T cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs2204008 0.688 rs12824232 chr12:38175901 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT trans rs7618501 0.501 rs7627864 chr3:49926613 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.36 0.6 1.06e-13 Intelligence (multi-trait analysis); TGCT cis rs933688 1.000 rs6867219 chr5:90718008 T/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.65e-14 Smoking behavior; TGCT cis rs1865760 0.928 rs9295673 chr6:25912094 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.67 6.39 0.5 3.03e-9 Height; TGCT cis rs74233809 0.901 rs3824755 chr10:104595849 G/C cg05855489 chr10:104503620 C10orf26 0.83 4.75 0.39 5.63e-6 Birth weight; TGCT cis rs4689388 0.890 rs4501291 chr4:6298582 C/T cg14416269 chr4:6271139 WFS1 0.4 5.32 0.43 4.78e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs75686122 0.892 rs1426288 chr8:104578464 C/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7591446 0.517 rs13427985 chr2:45838840 C/A cg15146906 chr2:45838581 SRBD1 0.73 4.94 0.41 2.45e-6 Squamous cell lung carcinoma; TGCT cis rs909002 0.800 rs1056526 chr1:32084904 C/T cg11573219 chr1:32083031 HCRTR1 -0.45 -5.86 -0.47 3.83e-8 Intelligence (multi-trait analysis); TGCT cis rs2479724 0.901 rs33954419 chr6:41786136 A/G cg08135965 chr6:41755394 TOMM6 0.51 4.91 0.4 2.81e-6 Menarche (age at onset); TGCT cis rs4563143 0.663 rs10417671 chr19:29235335 T/C cg14983838 chr19:29218262 NA 0.76 6.86 0.52 2.94e-10 Methadone dose in opioid dependence; TGCT cis rs9972944 0.756 rs7212901 chr17:63766499 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.16 -0.42 9.6e-7 Total body bone mineral density; TGCT cis rs1971762 0.762 rs7312853 chr12:54073597 C/G cg09709951 chr12:54017699 ATF7 -0.35 -5.36 -0.43 3.85e-7 Height; TGCT cis rs67072384 0.818 rs2291290 chr11:72465877 T/C cg03713592 chr11:72463424 ARAP1 -0.93 -4.68 -0.39 7.3e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs3858526 0.959 rs10838797 chr11:5920977 A/G cg05234568 chr11:5960015 NA -0.44 -4.61 -0.38 9.91e-6 DNA methylation (variation); TGCT cis rs9486719 1.000 rs11756315 chr6:97008678 A/G cg06623918 chr6:96969491 KIAA0776 0.94 7.9 0.58 1.31e-12 Migraine;Coronary artery disease; TGCT cis rs1153858 1.000 rs8042786 chr15:45703539 T/C cg26924012 chr15:45694286 SPATA5L1 1.1 15.34 0.81 2.01e-30 Homoarginine levels; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg21226059 chr5:178986404 RUFY1 0.63 7.74 0.57 2.98e-12 Lung cancer; TGCT cis rs6671200 1.000 rs12755552 chr1:95685026 A/G cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs2239547 0.657 rs7620706 chr3:52891756 A/T cg11645453 chr3:52864694 ITIH4 0.35 5.88 0.47 3.57e-8 Schizophrenia; TGCT cis rs950169 0.526 rs698620 chr15:85177208 G/A cg12863693 chr15:85201151 NMB -0.41 -5.67 -0.45 9.49e-8 Schizophrenia; TGCT cis rs1723838 0.510 rs2735572 chr11:73688492 C/T cg26954736 chr11:73693896 UCP2 -1.29 -6.15 -0.48 9.74e-9 Obesity-related traits; TGCT cis rs4234284 0.556 rs34147515 chr3:126965137 G/C cg25436886 chr3:127056972 NA -0.5 -4.87 -0.4 3.26e-6 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs826838 1.000 rs1719848 chr12:39085586 A/G cg13010199 chr12:38710504 ALG10B -0.59 -4.89 -0.4 3e-6 Heart rate; TGCT trans rs17685 0.796 rs3757594 chr7:75678644 G/A cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT trans rs17685 0.753 rs4398845 chr7:75716781 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 8.89 0.62 5.86e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs514406 0.644 rs928451 chr1:53195800 A/G cg16325326 chr1:53192061 ZYG11B -0.89 -13.12 -0.76 3.31e-25 Monocyte count; TGCT cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.65 6.06 0.48 1.53e-8 Bipolar disorder; TGCT cis rs6089829 0.962 rs6089826 chr20:61668595 G/A cg03213289 chr20:61660250 NA 0.7 10.08 0.67 8.1e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs9457247 0.935 rs1187530 chr6:167376812 C/T cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.06e-6 Crohn's disease; TGCT cis rs2075371 0.932 rs2241332 chr7:133969439 A/G cg11752832 chr7:134001865 SLC35B4 0.6 5.11 0.42 1.21e-6 Mean platelet volume; TGCT cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg13695892 chr22:41940480 POLR3H -0.91 -8.86 -0.62 6.93e-15 Vitiligo; TGCT cis rs7089973 0.604 rs7903663 chr10:116609904 G/A cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs1372520 0.684 rs3113355 chr4:90745345 A/T cg15133208 chr4:90757351 SNCA -0.49 -5.69 -0.45 8.67e-8 Neuroticism; TGCT cis rs3784262 0.742 rs28379349 chr15:58202494 A/G cg12031962 chr15:58353849 ALDH1A2 0.52 7.48 0.56 1.18e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7246657 0.943 rs10420722 chr19:37973774 C/G cg18154014 chr19:37997991 ZNF793 0.96 6.63 0.51 9.4e-10 Coronary artery calcification; TGCT cis rs7829975 0.714 rs4841040 chr8:8654527 T/C cg06636001 chr8:8085503 FLJ10661 0.68 5.82 0.46 4.67e-8 Mood instability; TGCT trans rs1005277 0.579 rs2472173 chr10:38374638 G/A cg17830980 chr10:43048298 ZNF37B -0.87 -11.04 -0.7 3.63e-20 Extrinsic epigenetic age acceleration; TGCT cis rs4674676 1 rs4674676 chr2:223529112 A/G cg25565276 chr2:223520875 FARSB 1.05 8.28 0.6 1.67e-13 Chin dimples; TGCT cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs3808502 0.563 rs12549144 chr8:11422861 C/G cg21775007 chr8:11205619 TDH 0.5 4.52 0.38 1.42e-5 Neuroticism; TGCT cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg11905131 chr22:24372483 LOC391322 -0.95 -11.15 -0.71 2.06e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9309473 0.607 rs7567017 chr2:73596270 C/T cg20560298 chr2:73613845 ALMS1 -0.41 -4.54 -0.38 1.31e-5 Metabolite levels; TGCT cis rs73198271 1.000 rs4840356 chr8:8607527 A/G ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.56 -0.38 1.23e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1018836 0.608 rs6982329 chr8:91467488 A/G cg16814680 chr8:91681699 NA -0.72 -7.54 -0.56 8.6e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2439831 0.702 rs16977724 chr15:44151299 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.86 5.92 0.47 3e-8 Lung cancer in ever smokers; TGCT cis rs10791097 0.748 rs4937580 chr11:130734270 T/C cg12179176 chr11:130786555 SNX19 0.8 9.62 0.65 1.07e-16 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6089829 0.855 rs4809459 chr20:61661345 C/T cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg17971929 chr21:40555470 PSMG1 0.97 9.4 0.65 3.57e-16 Cognitive function; TGCT cis rs4665809 0.877 rs34536218 chr2:26287376 T/A cg22920501 chr2:26401640 FAM59B 0.74 5.78 0.46 5.68e-8 Gut microbiome composition (summer); TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg14159672 chr1:205819179 PM20D1 0.6 7.44 0.56 1.42e-11 Menarche (age at onset); TGCT cis rs9640161 0.711 rs3800781 chr7:150027324 T/A cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 8.99e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs4819052 0.851 rs7279011 chr21:46655995 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.76 0.39 5.4e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7226408 0.857 rs72892509 chr18:34661797 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs11677370 0.963 rs6720814 chr2:3817590 A/C cg17052675 chr2:3827356 NA -0.3 -5.2 -0.42 7.86e-7 Type 2 diabetes; TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg25767906 chr1:53392781 SCP2 -0.58 -7.3 -0.55 3.08e-11 Monocyte count; TGCT cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg03264133 chr6:25882463 NA -0.49 -5.14 -0.42 1.06e-6 Height; TGCT cis rs7666738 0.570 rs10032272 chr4:99095601 T/C cg05340658 chr4:99064831 C4orf37 0.43 4.62 0.38 9.29e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg18230493 chr5:56204884 C5orf35 -0.67 -5.88 -0.47 3.5e-8 Initial pursuit acceleration; TGCT cis rs7119038 0.818 rs6421571 chr11:118743772 T/C cg19308663 chr11:118741387 NA -0.32 -6.29 -0.49 5.03e-9 Sjögren's syndrome; TGCT cis rs61990749 0.597 rs8016447 chr14:78222068 C/T cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs7568458 0.709 rs11895401 chr2:85753847 C/T cg02493740 chr2:85810744 VAMP5 -0.29 -5.7 -0.46 8.09e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9393692 0.905 rs9379838 chr6:26277133 C/T cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT cis rs71597109 0.639 rs35416717 chr4:102726657 C/A cg14855874 chr4:102712397 BANK1 0.42 4.82 0.4 4.16e-6 Chronic lymphocytic leukemia; TGCT cis rs10504229 1.000 rs112284078 chr8:58191640 A/G cg24829409 chr8:58192753 C8orf71 -0.57 -5.35 -0.43 4.14e-7 Developmental language disorder (linguistic errors); TGCT cis rs763121 0.853 rs5757204 chr22:39046700 A/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg03188948 chr7:1209495 NA 0.45 5.97 0.47 2.34e-8 Longevity;Endometriosis; TGCT cis rs9905704 0.624 rs8080071 chr17:57093825 C/T cg05425664 chr17:57184151 TRIM37 0.68 5.61 0.45 1.25e-7 Testicular germ cell tumor; TGCT cis rs9649213 0.559 rs56997921 chr7:98009224 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.78 -0.62 1.09e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs1018836 0.923 rs10956748 chr8:91621537 T/A cg16814680 chr8:91681699 NA -0.86 -9.19 -0.64 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs8177253 0.574 rs6775042 chr3:133442245 G/T cg01448562 chr3:133502909 NA -0.28 -5.27 -0.43 5.8e-7 Iron status biomarkers; TGCT cis rs2115630 1.000 rs11854313 chr15:85304048 G/C cg17173187 chr15:85201210 NMB -0.39 -4.76 -0.39 5.4e-6 P wave terminal force; TGCT cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs643506 1.000 rs647080 chr11:111609174 A/G cg09085632 chr11:111637200 PPP2R1B 0.55 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs1903068 0.853 rs17773240 chr4:55999781 T/C cg16572876 chr4:56024045 NA 0.43 4.94 0.41 2.43e-6 Endometriosis; TGCT cis rs7666738 0.830 rs10017557 chr4:98983969 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4273100 0.512 rs1355128 chr17:19299144 G/A cg01534423 chr17:18965556 NA -0.76 -7.9 -0.58 1.31e-12 Schizophrenia; TGCT cis rs9467711 0.591 rs76091509 chr6:26706602 T/A cg16898833 chr6:26189333 HIST1H4D 1.53 5.95 0.47 2.55e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs3824867 0.920 rs7111873 chr11:47469439 A/G cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs9322193 0.923 rs9688517 chr6:150061791 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2637266 0.714 rs7082421 chr10:78446313 G/A cg18941641 chr10:78392320 NA 0.36 4.49 0.37 1.58e-5 Pulmonary function; TGCT cis rs1757171 0.542 rs1757186 chr6:37484111 A/G cg25019722 chr6:37503610 NA -0.51 -7.96 -0.58 9.09e-13 Cognitive performance; TGCT cis rs7666738 0.715 rs3857216 chr4:99032129 G/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6540559 0.611 rs11810817 chr1:210011747 C/G cg22029157 chr1:209979665 IRF6 0.68 4.88 0.4 3.22e-6 Cleft lip with or without cleft palate; TGCT cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs854624 0.792 rs1719197 chr17:34336876 T/C cg02022384 chr17:34097390 MMP28 0.53 4.77 0.39 5.12e-6 Blood protein levels; TGCT cis rs5769765 0.955 rs9616204 chr22:50303530 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.17 -11.76 -0.73 6.61e-22 Schizophrenia; TGCT cis rs2153535 0.546 rs1335640 chr6:8485325 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1372520 0.623 rs2583975 chr4:90748488 T/C cg01966878 chr4:90757139 SNCA -0.3 -4.64 -0.38 8.54e-6 Neuroticism; TGCT cis rs17376456 0.825 rs13156202 chr5:93157721 C/T cg21475434 chr5:93447410 FAM172A -0.61 -4.75 -0.39 5.52e-6 Diabetic retinopathy; TGCT cis rs56114371 0.777 rs200482 chr6:27773904 G/A cg10876282 chr6:28092338 ZSCAN16 0.76 4.53 0.38 1.38e-5 Breast cancer; TGCT cis rs9787249 0.874 rs7520588 chr1:40214525 T/A cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs9527 0.545 rs35756290 chr10:104585572 G/A cg15744005 chr10:104629667 AS3MT -0.47 -5.6 -0.45 1.33e-7 Arsenic metabolism; TGCT cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs72843506 0.656 rs9901357 chr17:20009042 A/C cg18979559 chr17:20280153 CCDC144C -0.63 -4.52 -0.38 1.45e-5 Schizophrenia; TGCT cis rs2235642 0.891 rs2281231 chr16:1601879 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.72 -0.39 6.19e-6 Coronary artery disease; TGCT cis rs12776158 0.901 rs79980322 chr10:71201715 C/T cg12610070 chr10:71211762 TSPAN15 -0.58 -5.04 -0.41 1.64e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs10779751 0.686 rs1148478 chr1:11174067 A/T cg08854313 chr1:11322531 MTOR 0.82 6.58 0.51 1.17e-9 Body mass index; TGCT cis rs7267979 1.000 rs2259873 chr20:25280781 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.1 0.42 1.24e-6 Menopause (age at onset); TGCT cis rs76419734 0.614 rs17036097 chr4:106597295 G/C cg24545054 chr4:106630052 GSTCD;INTS12 0.74 4.9 0.4 2.88e-6 Post bronchodilator FEV1; TGCT cis rs9899728 0.764 rs9660 chr17:73038746 A/G cg27626185 chr17:73056755 KCTD2 -0.61 -5.6 -0.45 1.32e-7 Alzheimer's disease or small vessel stroke; TGCT cis rs2760061 0.819 rs3094914 chr1:228206934 C/T cg02753203 chr1:228287806 NA 0.3 5.71 0.46 8.06e-8 Diastolic blood pressure; TGCT cis rs3008870 0.755 rs2755243 chr1:67482783 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.81 8.4 0.6 8.51e-14 Lymphocyte percentage of white cells; TGCT cis rs17076896 0.786 rs56682920 chr13:19937751 A/G cg00777926 chr13:20807375 GJB6 -0.41 -4.82 -0.4 4.03e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2797160 1.000 rs1739374 chr6:126011825 C/T cg05901451 chr6:126070800 HEY2 0.72 5.91 0.47 3.15e-8 Endometrial cancer; TGCT cis rs55665837 0.559 rs9667144 chr11:14421101 C/T cg19336497 chr11:14380999 RRAS2 0.33 4.97 0.41 2.2e-6 Vitamin D levels; TGCT cis rs2354432 0.599 rs6693667 chr1:146817245 A/T cg25205988 chr1:146714368 CHD1L 1.17 7.25 0.55 3.84e-11 Mitochondrial DNA levels; TGCT cis rs9300255 0.510 rs1790133 chr12:123698518 T/G cg00376283 chr12:123451042 ABCB9 0.71 5.52 0.44 1.88e-7 Neutrophil percentage of white cells; TGCT cis rs2816062 0.813 rs742485 chr1:18900943 A/T cg18795169 chr1:18902165 NA -0.6 -13.84 -0.78 6.55e-27 Urate levels in lean individuals; TGCT cis rs524281 0.692 rs2254388 chr11:65837599 C/T cg00563793 chr11:65837595 PACS1 -0.57 -5.33 -0.43 4.54e-7 Electroencephalogram traits; TGCT cis rs2072499 1.000 rs2540173 chr1:156188214 A/G cg06970220 chr1:156163860 SLC25A44 0.67 5.98 0.47 2.22e-8 Testicular germ cell tumor; TGCT cis rs7666738 0.791 rs4440223 chr4:99044796 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2073300 1.000 rs6137962 chr20:23443966 T/C cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs12484776 0.677 rs8136269 chr22:40532444 G/C cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs1008375 1.000 rs10939740 chr4:17617490 T/C cg16339924 chr4:17578868 LAP3 0.63 5.23 0.43 6.91e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs66573146 1.000 rs9942188 chr4:6984181 C/T cg01220768 chr4:7056774 TADA2B 0.39 4.91 0.4 2.77e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Vitiligo; TGCT cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs11190604 1.000 rs10786597 chr10:102291287 C/T cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2663905 0.664 rs2460855 chr15:81361729 G/T cg18028999 chr15:81426610 C15orf26 -0.55 -5.05 -0.41 1.57e-6 QT interval (drug interaction); TGCT cis rs1568889 1.000 rs11604085 chr11:28141002 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 9.0 0.63 3.18e-15 Bipolar disorder; TGCT cis rs3008870 1.000 rs3008858 chr1:67390416 G/C cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg11502198 chr6:26597334 ABT1 -0.56 -4.88 -0.4 3.23e-6 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs9549260 0.755 rs3900833 chr13:41188292 A/G cg21288729 chr13:41239152 FOXO1 1.0 10.06 0.67 9.29e-18 Red blood cell count; TGCT cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs9527 0.567 rs11191573 chr10:104896816 T/C cg04362960 chr10:104952993 NT5C2 0.69 5.82 0.46 4.78e-8 Arsenic metabolism; TGCT cis rs17331151 0.573 rs28552648 chr3:52865593 G/A cg15956490 chr3:53032818 SFMBT1 0.46 5.75 0.46 6.57e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11098499 0.754 rs28652763 chr4:120242312 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs826838 0.967 rs2892410 chr12:38990282 A/G cg26384229 chr12:38710491 ALG10B -0.98 -9.59 -0.65 1.22e-16 Heart rate; TGCT cis rs3027009 0.881 rs61828174 chr1:159134846 T/A cg24432768 chr1:158149974 CD1D -0.5 -4.54 -0.38 1.31e-5 Lean body mass and age at menarche (combined); TGCT cis rs600231 0.708 rs2957268 chr11:65245816 A/G cg17120908 chr11:65337727 SSSCA1 -0.55 -5.14 -0.42 1.03e-6 Bone mineral density; TGCT cis rs875971 0.825 rs1860472 chr7:66082723 T/C cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.89e-6 Aortic root size; TGCT cis rs713587 0.525 rs1541984 chr2:25082414 G/A cg01884057 chr2:25150051 NA 0.3 5.87 0.47 3.8e-8 Body mass index in non-asthmatics; TGCT cis rs7819412 0.669 rs7823349 chr8:10998630 G/T cg21775007 chr8:11205619 TDH -0.55 -5.05 -0.41 1.53e-6 Triglycerides; TGCT cis rs4819052 1.000 rs2838830 chr21:46664227 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.87 7.26 0.55 3.73e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4727027 0.704 rs12704070 chr7:148902789 G/A cg23583168 chr7:148888333 NA -0.81 -10.9 -0.7 7.99e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6684514 1.000 rs59468948 chr1:156288058 A/T cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4975709 0.569 rs1684965 chr5:1865248 A/G cg04156016 chr5:1868137 NA 0.33 4.81 0.4 4.32e-6 Cardiovascular disease risk factors; TGCT cis rs7216064 0.953 rs11868959 chr17:65840810 T/C cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1903068 0.657 rs10026340 chr4:55998136 G/A cg01777861 chr4:56023843 NA 0.55 5.98 0.47 2.23e-8 Endometriosis; TGCT cis rs3087591 0.708 rs7350943 chr17:29684553 C/T cg24425628 chr17:29625626 OMG;NF1 0.39 5.56 0.45 1.57e-7 Hip circumference; TGCT cis rs8008270 0.689 rs8012109 chr14:53399337 C/T cg01926858 chr14:53619558 DDHD1 -0.74 -4.47 -0.37 1.76e-5 Prostate cancer; TGCT cis rs7914558 0.966 rs943035 chr10:104839152 T/C cg04362960 chr10:104952993 NT5C2 0.6 5.32 0.43 4.64e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs13188771 0.578 rs67960514 chr5:100905390 G/A cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT trans rs1814175 0.527 rs3974435 chr11:49619533 G/A cg11707556 chr5:10655725 ANKRD33B -0.41 -8.24 -0.59 2.03e-13 Height; TGCT cis rs2361718 0.500 rs8064429 chr17:78096187 A/C cg09238746 chr17:78121135 EIF4A3 -0.9 -8.28 -0.6 1.69e-13 Yeast infection; TGCT cis rs1008375 0.966 rs12509962 chr4:17680292 G/A cg16339924 chr4:17578868 LAP3 0.52 4.57 0.38 1.16e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.63 0.51 9.08e-10 Electroencephalogram traits; TGCT cis rs9549367 0.789 rs2287248 chr13:113889226 T/C cg00898013 chr13:113819073 PROZ -0.4 -4.92 -0.4 2.7e-6 Platelet distribution width; TGCT cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg03188948 chr7:1209495 NA 0.64 5.38 0.43 3.61e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6977660 0.507 rs4721822 chr7:19771693 T/C cg05791153 chr7:19748676 TWISTNB 1.0 6.66 0.51 8e-10 Thyroid stimulating hormone; TGCT cis rs10927875 0.722 rs1763605 chr1:16338925 T/G cg14742211 chr1:16348397 CLCNKA 0.19 4.53 0.38 1.37e-5 Dilated cardiomyopathy; TGCT cis rs9399137 0.507 rs13197750 chr6:135312380 G/A cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs2242116 0.896 rs724448 chr3:46935734 A/C cg23352942 chr3:46931381 PTH1R -0.37 -5.81 -0.46 5.02e-8 Birth weight; TGCT cis rs7584330 0.955 rs7581882 chr2:238390745 T/C cg08992911 chr2:238395768 MLPH 0.67 5.44 0.44 2.69e-7 Prostate cancer; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg12419862 chr22:24373484 LOC391322 -0.83 -7.5 -0.56 1.09e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs950169 0.881 rs62029596 chr15:84955434 A/G cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs7582180 0.764 rs13006224 chr2:100917109 C/T cg14675211 chr2:100938903 LONRF2 0.51 4.96 0.41 2.31e-6 Intelligence (multi-trait analysis); TGCT trans rs1005277 0.579 rs2474587 chr10:38420666 C/T cg17830980 chr10:43048298 ZNF37B -0.85 -11.06 -0.7 3.31e-20 Extrinsic epigenetic age acceleration; TGCT cis rs9807989 0.839 rs9308857 chr2:102979624 G/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs8072100 0.790 rs7222225 chr17:45693497 A/G cg08085267 chr17:45401833 C17orf57 0.46 5.01 0.41 1.82e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.69 0.62 1.83e-14 Platelet count; TGCT cis rs6500602 0.647 rs1659497 chr16:4594635 G/A cg08645402 chr16:4508243 NA -0.18 -5.06 -0.41 1.47e-6 Schizophrenia; TGCT cis rs3858526 0.628 rs1840177 chr11:5944627 T/G cg05234568 chr11:5960015 NA 0.52 5.61 0.45 1.26e-7 DNA methylation (variation); TGCT cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg27286337 chr10:134555280 INPP5A 0.45 5.3 0.43 5.05e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg02493798 chr17:6899577 ALOX12 0.43 4.65 0.39 8.35e-6 Tonsillectomy; TGCT cis rs4072705 0.835 rs7855360 chr9:127556704 C/T cg13476313 chr9:127244764 NR5A1 0.29 4.73 0.39 5.9e-6 Menarche (age at onset); TGCT cis rs360798 0.512 rs17027429 chr2:63079983 C/T cg17519650 chr2:63277830 OTX1 0.65 5.98 0.47 2.23e-8 Coronary artery disease; TGCT cis rs17376456 0.825 rs6874766 chr5:93213807 C/G cg21475434 chr5:93447410 FAM172A -0.66 -4.7 -0.39 6.94e-6 Diabetic retinopathy; TGCT cis rs10782582 0.609 rs1001160 chr1:76358591 A/C cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg05457628 chr5:178986728 RUFY1 0.46 5.08 0.42 1.33e-6 Lung cancer; TGCT cis rs1552244 0.882 rs112621205 chr3:10017916 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs7267979 0.844 rs2474780 chr20:25285835 G/A cg14121845 chr20:25566513 NINL 0.45 4.6 0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6831352 0.918 rs29001202 chr4:100053782 T/A cg12011299 chr4:100065546 ADH4 -0.41 -4.96 -0.41 2.29e-6 Alcohol dependence; TGCT cis rs4665809 1.000 rs6739061 chr2:26256147 C/T cg22920501 chr2:26401640 FAM59B -0.71 -6.1 -0.48 1.27e-8 Gut microbiome composition (summer); TGCT cis rs2795502 1.000 rs2795508 chr10:43353555 G/T cg20628663 chr10:43360327 NA 0.41 6.18 0.49 8.51e-9 Blood protein levels; TGCT cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs3125734 0.633 rs3765002 chr10:64006124 G/T cg19640130 chr10:64028056 RTKN2 -0.39 -5.04 -0.41 1.57e-6 Rheumatoid arthritis; TGCT cis rs9902453 1.000 rs7221743 chr17:28407876 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -6.77 -0.52 4.55e-10 Coffee consumption (cups per day); TGCT cis rs7949030 0.626 rs11231145 chr11:62328854 G/A cg11742103 chr11:62369870 EML3;MTA2 0.61 8.71 0.62 1.65e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1903068 0.614 rs9998950 chr4:55996845 C/T cg09978860 chr4:56023921 NA 0.54 5.58 0.45 1.43e-7 Endometriosis; TGCT cis rs1541995 0.830 rs7171424 chr15:96266446 A/G cg00882281 chr15:96346592 NA 0.29 4.45 0.37 1.92e-5 Photic sneeze reflex; TGCT cis rs7681440 0.647 rs4522832 chr4:90819391 A/C cg10208370 chr4:90758469 SNCA -0.57 -5.39 -0.44 3.46e-7 Dementia with Lewy bodies; TGCT trans rs7698623 0.850 rs4693895 chr4:88797839 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs916888 0.610 rs199454 chr17:44800110 G/A cg15921436 chr17:44337874 NA -0.4 -6.15 -0.48 9.83e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7829975 0.774 rs57312668 chr8:8680477 G/A cg08975724 chr8:8085496 FLJ10661 0.53 4.74 0.39 5.88e-6 Mood instability; TGCT cis rs1577917 0.771 rs9450290 chr6:86233397 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.6 5.27 0.43 5.84e-7 Response to antipsychotic treatment; TGCT cis rs7666738 0.830 rs35560671 chr4:99069095 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.808 rs2246697 chr21:46689999 G/A cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs2469997 1.000 rs2447164 chr8:120371887 G/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 4.92 0.4 2.75e-6 Menopause (age at onset); TGCT cis rs2019216 0.564 rs907707 chr17:21910083 G/C cg22648282 chr17:21454238 C17orf51 -0.56 -5.45 -0.44 2.57e-7 Pelvic organ prolapse; TGCT cis rs4862750 0.872 rs7664463 chr4:187876686 A/C cg11301795 chr4:187892539 NA -0.32 -4.92 -0.4 2.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.791 rs62318907 chr4:99037120 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs478304 0.619 rs10791822 chr11:65428706 T/C cg27068330 chr11:65405492 SIPA1 -1.0 -10.96 -0.7 5.91e-20 Acne (severe); TGCT cis rs208520 0.545 rs10944874 chr6:66752080 C/T cg07460842 chr6:66804631 NA -1.02 -13.72 -0.78 1.27e-26 Exhaled nitric oxide output; TGCT cis rs7617773 0.539 rs13082217 chr3:48383264 T/C cg11946769 chr3:48343235 NME6 0.57 4.83 0.4 4.01e-6 Coronary artery disease; TGCT cis rs2249625 0.545 rs60835713 chr6:72880349 T/C cg08500200 chr6:72892038 RIMS1 0.43 4.61 0.38 1e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs7552404 0.924 rs1251075 chr1:76190569 C/G cg03433033 chr1:76189801 ACADM 0.77 9.35 0.64 4.77e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1577917 1.000 rs10944169 chr6:86683036 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.69 -5.59 -0.45 1.36e-7 Response to antipsychotic treatment; TGCT cis rs7208859 0.673 rs3816780 chr17:29161358 C/T cg14008862 chr17:28927542 LRRC37B2 0.77 4.52 0.38 1.44e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs909674 0.775 rs4821896 chr22:39833437 T/C cg05872129 chr22:39784769 NA -1.0 -9.74 -0.66 5.52e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs17601876 0.814 rs3889391 chr15:51558422 G/A cg19946085 chr15:51559439 CYP19A1 -0.31 -4.46 -0.37 1.78e-5 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs514406 0.861 rs4926932 chr1:53247495 C/T cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs1524927 1.000 rs13310130 chr7:96346088 T/G cg03808172 chr7:96339361 SHFM1 0.49 5.06 0.41 1.45e-6 Total body bone mineral density; TGCT cis rs2180341 0.596 rs12215298 chr6:127676833 C/T cg24812749 chr6:127587940 RNF146 0.67 5.53 0.44 1.84e-7 Breast cancer; TGCT cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg21724239 chr8:58056113 NA 0.5 5.39 0.44 3.35e-7 Developmental language disorder (linguistic errors); TGCT cis rs758129 0.501 rs2072266 chr15:89866954 A/G cg24365117 chr15:89879190 POLG 0.35 4.76 0.39 5.4e-6 Schizophrenia; TGCT cis rs5769707 0.706 rs2071903 chr22:50034517 G/A cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 4.88e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2486012 1.000 rs3120805 chr1:44406113 C/T cg12908607 chr1:44402522 ARTN 0.78 6.04 0.48 1.68e-8 Intelligence (multi-trait analysis); TGCT cis rs13191362 1.000 rs13201023 chr6:162981381 C/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.73 0.46 7.24e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3796352 1.000 rs11712653 chr3:53070875 A/C cg15956490 chr3:53032818 SFMBT1 -0.61 -8.26 -0.6 1.91e-13 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7918232 0.662 rs10741125 chr10:27288925 G/A cg14442939 chr10:27389572 ANKRD26 0.58 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg23708337 chr7:1209742 NA 0.64 6.18 0.49 8.61e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs394563 0.726 rs6922130 chr6:149672375 C/G cg16235748 chr6:149772707 ZC3H12D 0.48 5.53 0.44 1.8e-7 Dupuytren's disease; TGCT cis rs9296092 0.517 rs11752179 chr6:33534713 G/T cg13560919 chr6:33536144 NA -0.23 -4.95 -0.41 2.4e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6500602 0.627 rs841231 chr16:4583147 C/T cg06139259 chr16:4526053 HMOX2;NMRAL1 -0.26 -4.76 -0.39 5.36e-6 Schizophrenia; TGCT cis rs3784262 1.000 rs12915901 chr15:58279432 G/A cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.82 -0.57 1.96e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9325144 0.647 rs34963631 chr12:38912260 T/A cg26384229 chr12:38710491 ALG10B -0.6 -5.48 -0.44 2.31e-7 Morning vs. evening chronotype; TGCT cis rs938554 0.571 rs12509955 chr4:10024303 C/T cg11266682 chr4:10021025 SLC2A9 -0.57 -5.45 -0.44 2.59e-7 Blood metabolite levels; TGCT trans rs1005277 0.579 rs1780130 chr10:38485378 T/A cg17830980 chr10:43048298 ZNF37B -0.83 -10.33 -0.68 2.02e-18 Extrinsic epigenetic age acceleration; TGCT cis rs2290402 0.536 rs4690336 chr4:867242 A/G cg23332689 chr4:987652 IDUA;SLC26A1 -0.29 -4.44 -0.37 1.97e-5 Type 2 diabetes; TGCT cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg11494091 chr17:61959527 GH2 0.6 13.05 0.76 5.09e-25 Prudent dietary pattern; TGCT cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg06238570 chr21:40685208 BRWD1 -0.8 -9.11 -0.63 1.74e-15 Cognitive function; TGCT cis rs3733585 0.648 rs13103497 chr4:9979262 A/G cg11266682 chr4:10021025 SLC2A9 0.59 7.62 0.56 5.7e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs344364 0.511 rs1742463 chr16:1946110 A/G cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs4919669 0.668 rs10883761 chr10:104420018 A/G cg05855489 chr10:104503620 C10orf26 0.8 4.59 0.38 1.05e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs713587 0.713 rs12618252 chr2:25207950 G/A cg15423357 chr2:25149977 NA -0.58 -5.9 -0.47 3.16e-8 Body mass index in non-asthmatics; TGCT cis rs12134245 0.776 rs13447464 chr1:91968278 G/A cg02896835 chr1:92012615 NA -0.29 -4.8 -0.4 4.47e-6 Breast cancer; TGCT trans rs12599106 0.679 rs34584967 chr16:34475725 T/G cg21548813 chr6:291882 DUSP22 -0.64 -6.85 -0.52 3.04e-10 Menopause (age at onset); TGCT cis rs28830936 0.509 rs6493005 chr15:41859152 A/G cg17847044 chr15:42102381 MAPKBP1 -0.19 -4.77 -0.39 5.07e-6 Diastolic blood pressure; TGCT cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.03 0.41 1.71e-6 Menopause (age at onset); TGCT cis rs7226408 0.857 rs11659681 chr18:34458035 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg05368731 chr17:41323189 NBR1 1.1 11.24 0.71 1.23e-20 Menopause (age at onset); TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs1670533 0.685 rs56019586 chr4:1059842 C/G cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs7949030 0.591 rs12049914 chr11:62369436 C/G cg22862634 chr11:62369728 EML3;MTA2 0.7 8.89 0.62 5.98e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT trans rs916888 0.773 rs199439 chr17:44793503 A/G cg22968622 chr17:43663579 NA 1.29 11.02 0.7 4.06e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6988636 0.534 rs62521778 chr8:124122794 T/G cg27053337 chr8:124217698 FAM83A 0.56 4.83 0.4 3.91e-6 Urinary uromodulin levels; TGCT cis rs651907 0.557 rs7629753 chr3:101371922 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.53 -5.03 -0.41 1.69e-6 Colorectal cancer; TGCT trans rs6089829 0.855 rs4809459 chr20:61661345 C/T cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9302065 0.681 rs9524902 chr13:95963518 C/T cg24476569 chr13:95954382 ABCC4 -0.45 -6.36 -0.5 3.61e-9 Blood metabolite levels; TGCT cis rs4803468 1.000 rs3810174 chr19:41904165 C/T cg09537434 chr19:41945824 ATP5SL -0.89 -10.04 -0.67 9.93e-18 Height; TGCT cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs1862618 0.525 rs832403 chr5:56265992 G/T cg24549020 chr5:56110836 MAP3K1 -0.69 -4.96 -0.41 2.29e-6 Initial pursuit acceleration; TGCT cis rs7659604 0.560 rs769238 chr4:122744942 G/A cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.24e-7 Type 2 diabetes; TGCT cis rs5769707 0.837 rs5769709 chr22:50021757 C/T cg20744362 chr22:50050164 C22orf34 0.28 4.54 0.38 1.32e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2933343 1.000 rs1683811 chr3:128612113 A/C cg11901034 chr3:128598214 ACAD9 -0.64 -5.05 -0.41 1.56e-6 IgG glycosylation; TGCT trans rs7618501 0.722 rs9853458 chr3:49783211 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs1371867 0.846 rs1660312 chr8:101330634 C/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.55 -0.38 1.24e-5 Atrioventricular conduction; TGCT cis rs12477438 0.798 rs7570657 chr2:99654281 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs7611238 0.560 rs62288365 chr3:195110720 T/C cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.81e-6 Body mass index; TGCT cis rs7267979 1.000 rs6107033 chr20:25363591 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg05896524 chr21:47604654 C21orf56 0.42 4.45 0.37 1.91e-5 Testicular germ cell tumor; TGCT cis rs6121246 0.529 rs6060210 chr20:30187681 C/T cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs4253772 0.591 rs8143066 chr22:46656607 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.55 4.46 0.37 1.84e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs910187 0.537 rs6122556 chr20:45763924 T/A cg27589058 chr20:45804311 EYA2 -0.34 -6.29 -0.49 4.97e-9 Migraine; TGCT cis rs7772486 0.875 rs2814877 chr6:146299763 C/G cg23711669 chr6:146136114 FBXO30 0.87 9.35 0.64 4.65e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.704 rs7359501 chr17:56641200 C/T cg12560992 chr17:57184187 TRIM37 0.6 6.5 0.5 1.74e-9 Cognitive test performance; TGCT cis rs7727544 0.582 rs3749756 chr5:131534499 C/T cg24060327 chr5:131705240 SLC22A5 -0.44 -4.5 -0.37 1.56e-5 Blood metabolite levels; TGCT cis rs7666738 0.830 rs4699592 chr4:98974202 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs908922 0.676 rs12132469 chr1:152491856 G/T cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.16e-9 Hair morphology; TGCT cis rs9399135 0.967 rs1023179 chr6:135343829 T/A cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs2236918 0.710 rs2488470 chr1:242019580 A/G cg04158730 chr1:242011433 EXO1 0.57 5.33 0.43 4.4e-7 Menopause (age at onset); TGCT cis rs9807989 0.524 rs7594402 chr2:103021267 A/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT trans rs2727020 0.575 rs10769587 chr11:49549849 C/G cg03929089 chr4:120376271 NA -0.66 -7.6 -0.56 6.24e-12 Coronary artery disease; TGCT cis rs916888 0.773 rs199457 chr17:44795469 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.78 5.25 0.43 6.53e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2180341 0.883 rs6904630 chr6:127696869 A/G cg24812749 chr6:127587940 RNF146 0.99 7.63 0.57 5.24e-12 Breast cancer; TGCT cis rs9911578 0.967 rs4598970 chr17:57076893 T/A cg05425664 chr17:57184151 TRIM37 0.68 6.89 0.53 2.55e-10 Intelligence (multi-trait analysis); TGCT cis rs4746818 1.000 rs6480384 chr10:70890757 C/T cg11621586 chr10:70884670 VPS26A 1.21 10.66 0.69 3.17e-19 Left atrial antero-posterior diameter; TGCT cis rs36051895 0.695 rs59384377 chr9:5005034 A/T cg02405213 chr9:5042618 JAK2 -0.76 -10.25 -0.68 3.06e-18 Pediatric autoimmune diseases; TGCT cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg09359103 chr1:154839909 KCNN3 -0.67 -12.42 -0.74 1.61e-23 Prostate cancer; TGCT cis rs1023500 0.551 rs133379 chr22:42468535 A/G cg15557168 chr22:42548783 NA -0.21 -5.29 -0.43 5.31e-7 Schizophrenia; TGCT cis rs1552244 0.572 rs58862481 chr3:10164308 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.17 0.42 9.28e-7 Alzheimer's disease; TGCT cis rs11122272 0.766 rs2790870 chr1:231543823 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.71 -0.52 6.09e-10 Hemoglobin concentration; TGCT cis rs4824093 0.610 rs58671506 chr22:50288983 G/A cg20569369 chr22:51173646 NA 0.28 4.58 0.38 1.13e-5 Amyotrophic lateral sclerosis (sporadic); TGCT trans rs9650657 0.547 rs11250099 chr8:10818657 C/T cg06636001 chr8:8085503 FLJ10661 0.84 8.29 0.6 1.58e-13 Neuroticism; TGCT cis rs7843479 0.562 rs4872191 chr8:21824547 A/G cg17168535 chr8:21777572 XPO7 0.81 8.33 0.6 1.25e-13 Mean corpuscular volume; TGCT cis rs11621121 0.556 rs9635249 chr14:65797784 A/G cg04536575 chr14:65016802 C14orf50 -0.64 -4.57 -0.38 1.17e-5 N-glycan levels; TGCT cis rs6987853 0.933 rs6474401 chr8:42367068 T/C cg20539142 chr8:42623718 CHRNA6 0.19 4.46 0.37 1.83e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg03188948 chr7:1209495 NA 0.8 6.72 0.52 5.94e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg13695892 chr22:41940480 POLR3H -0.92 -9.33 -0.64 5.22e-16 Vitiligo; TGCT cis rs2013441 0.711 rs1682297 chr17:20384920 C/T cg18979559 chr17:20280153 CCDC144C 0.52 5.78 0.46 5.65e-8 Obesity-related traits; TGCT cis rs2070488 0.861 rs1858740 chr3:38438372 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.89 9.52 0.65 1.86e-16 Electrocardiographic conduction measures; TGCT cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg13732083 chr21:47605072 C21orf56 0.38 4.89 0.4 3.11e-6 Testicular germ cell tumor; TGCT cis rs12908161 1.000 rs58416181 chr15:85264461 G/A cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg04267008 chr7:1944627 MAD1L1 -0.34 -4.58 -0.38 1.13e-5 Bipolar disorder and schizophrenia; TGCT cis rs4144743 0.941 rs7211563 chr17:45324061 T/C cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT trans rs9295123 0.898 rs9347386 chr6:160571499 A/G cg22927510 chr22:50968328 TYMP -0.52 -6.96 -0.53 1.76e-10 Blood protein levels; TGCT cis rs7809950 0.954 rs2712229 chr7:107295326 T/A cg23024343 chr7:107201750 COG5 0.31 4.97 0.41 2.21e-6 Coronary artery disease; TGCT cis rs3782455 1.000 rs77542721 chr12:114402518 C/T cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9527 0.590 rs11191553 chr10:104851396 G/T cg15744005 chr10:104629667 AS3MT -0.42 -4.84 -0.4 3.82e-6 Arsenic metabolism; TGCT cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs858239 0.600 rs28483572 chr7:23131785 A/G cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2637266 0.905 rs7076442 chr10:78360480 A/C cg18941641 chr10:78392320 NA -0.41 -5.18 -0.42 8.65e-7 Pulmonary function; TGCT cis rs7829975 0.582 rs6982832 chr8:8792217 A/C cg15556689 chr8:8085844 FLJ10661 -0.67 -6.1 -0.48 1.26e-8 Mood instability; TGCT cis rs4237845 0.537 rs2002275 chr12:58283385 A/G cg23860436 chr12:58378763 NA 0.32 4.46 0.37 1.79e-5 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.887 rs4665825 chr2:26333100 A/G cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs17376456 0.877 rs9314100 chr5:93447394 T/C cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs28595532 0.764 rs55704595 chr4:119780607 G/A cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs427394 0.802 rs274698 chr5:6730957 T/G cg10857441 chr5:6722123 POLS -0.32 -7.93 -0.58 1.08e-12 Menopause (age at onset); TGCT cis rs2235642 0.717 rs9937922 chr16:1658154 C/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.29 -5.01 -0.41 1.8e-6 Coronary artery disease; TGCT cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg02353165 chr6:42928485 GNMT 0.94 9.63 0.65 1.01e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs11190604 1.000 rs17746014 chr10:102315354 T/C cg16342193 chr10:102329863 NA -0.39 -4.95 -0.41 2.35e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12497850 0.931 rs6442130 chr3:48778027 A/G cg18654377 chr3:49208889 KLHDC8B -0.4 -5.19 -0.42 8.44e-7 Parkinson's disease; TGCT cis rs1075232 1.000 rs72722829 chr15:31639114 G/A cg01030201 chr15:31746330 NA -1.01 -5.25 -0.43 6.38e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs295140 0.526 rs295113 chr2:201197816 C/G cg23649088 chr2:200775458 C2orf69 0.28 4.55 0.38 1.25e-5 QT interval; TGCT cis rs11677370 0.963 rs6720903 chr2:3817635 A/G cg17052675 chr2:3827356 NA -0.3 -5.2 -0.42 7.86e-7 Type 2 diabetes; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT trans rs2727020 0.575 rs10769587 chr11:49549849 C/G cg15704280 chr7:45808275 SEPT13 -0.61 -6.78 -0.52 4.26e-10 Coronary artery disease; TGCT cis rs7246657 0.722 rs8110865 chr19:38047387 G/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs6570726 0.846 rs439035 chr6:145887990 G/C cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3806843 0.548 rs246056 chr5:140325600 G/A cg07102913 chr5:140593443 PCDHB13 -0.46 -4.65 -0.39 8.2e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg11301795 chr4:187892539 NA -0.31 -4.79 -0.4 4.69e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg12751644 chr20:60527061 NA -0.39 -4.55 -0.38 1.27e-5 Body mass index; TGCT cis rs9329289 0.510 rs12359941 chr10:2547015 G/A cg07014206 chr10:2547000 NA -0.28 -4.66 -0.39 8.13e-6 Age-related hearing impairment; TGCT cis rs12220238 0.730 rs4746177 chr10:75913033 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.94 0.58 1.02e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2153535 0.580 rs9406170 chr6:8514153 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs4722166 0.564 rs1800797 chr7:22766221 A/G cg26061582 chr7:22766209 IL6 0.48 6.26 0.49 5.87e-9 Lung cancer; TGCT cis rs9436747 0.641 rs4655528 chr1:66049489 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.73 0.39 5.97e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs60154123 0.505 rs76426571 chr1:210041634 C/T cg23283495 chr1:209979779 IRF6 0.67 4.99 0.41 1.96e-6 Coronary artery disease; TGCT trans rs4942242 0.659 rs1105586 chr13:44232633 C/T cg19169023 chr15:41853346 TYRO3 0.35 6.63 0.51 9.24e-10 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs11696501 0.688 rs6073862 chr20:44331705 T/C cg16448223 chr20:44035136 DBNDD2;SYS1-DBNDD2 -0.62 -4.81 -0.4 4.31e-6 Brain structure; TGCT cis rs3784262 1.000 rs9325 chr15:58245986 A/T cg12031962 chr15:58353849 ALDH1A2 0.48 7.34 0.55 2.49e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9397585 0.759 rs6920313 chr6:153402841 T/C cg24028809 chr6:153414101 RGS17 0.22 4.58 0.38 1.11e-5 Body mass index; TGCT cis rs2013441 1.000 rs2703802 chr17:20101039 T/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg18538332 chr22:24372958 LOC391322 -1.0 -12.7 -0.75 3.51e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2302045 0.826 rs1444998 chr2:242053167 T/C cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs7752195 0.643 rs74983924 chr6:25248006 T/C cg16898833 chr6:26189333 HIST1H4D 1.17 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg03060546 chr3:49711283 APEH 0.52 5.7 0.46 8.28e-8 Parkinson's disease; TGCT cis rs12142240 0.698 rs112089006 chr1:46812360 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.84 0.46 4.33e-8 Menopause (age at onset); TGCT cis rs9814567 0.806 rs4245904 chr3:134321808 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs79057730 0.528 rs4719313 chr7:822501 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.31 0.43 4.93e-7 Initial pursuit acceleration; TGCT cis rs644799 0.931 rs496305 chr11:95567035 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 7.92 0.58 1.12e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9653442 0.704 rs10211595 chr2:100726476 G/C cg07810366 chr2:100720526 AFF3 -0.43 -7.11 -0.54 8.22e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7246657 0.722 rs2972458 chr19:38135403 T/C cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT cis rs1215050 0.547 rs6532690 chr4:98618571 C/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17270561 0.887 rs717551 chr6:25855624 T/C cg17042849 chr6:26104293 HIST1H4C -0.94 -6.13 -0.48 1.06e-8 Iron status biomarkers; TGCT cis rs1499614 1.000 rs60326618 chr7:66166358 G/A cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs7666738 0.830 rs13328005 chr4:99055480 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.53 0.56 9.25e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10206020 0.885 rs6720797 chr2:1574340 T/C cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg05215272 chr17:6899095 ALOX12 0.55 6.61 0.51 1.03e-9 Tonsillectomy; TGCT cis rs3008870 1.000 rs3008873 chr1:67425770 G/A cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs4455778 0.600 rs4461853 chr7:49090901 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs9388451 0.903 rs9388446 chr6:126064920 T/A cg10911889 chr6:126070802 HEY2 0.51 5.16 0.42 9.49e-7 Brugada syndrome; TGCT cis rs4494114 1.000 rs3790441 chr1:39352492 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.33 -0.49 4.16e-9 Blood protein levels; TGCT cis rs6088590 0.930 rs6087618 chr20:33288407 C/T cg08999081 chr20:33150536 PIGU 0.26 4.7 0.39 6.76e-6 Coronary artery disease; TGCT cis rs3764563 0.877 rs4019751 chr19:15740716 T/G cg20725493 chr19:15740067 CYP4F8 -0.43 -4.67 -0.39 7.75e-6 Inflammatory biomarkers; TGCT cis rs9916302 0.904 rs35285898 chr17:37555872 A/C cg15445000 chr17:37608096 MED1 -0.34 -4.8 -0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs6839277 chr4:99015563 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6740322 0.895 rs10210125 chr2:43556433 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.58 -0.51 1.17e-9 Coronary artery disease; TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg15383120 chr6:291909 DUSP22 -0.68 -7.03 -0.53 1.21e-10 Menopause (age at onset); TGCT cis rs4937076 1.000 rs1065398 chr11:125828007 T/C cg17967973 chr11:126139042 FOXRED1;SRPR -0.41 -4.57 -0.38 1.15e-5 Primary tooth development (time to first tooth eruption); TGCT cis rs9902453 0.967 rs12150261 chr17:28320473 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.73 -6.77 -0.52 4.69e-10 Coffee consumption (cups per day); TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg20052079 chr6:15504923 JARID2 0.95 5.79 0.46 5.55e-8 Gambling; TGCT cis rs72945132 0.882 rs17425511 chr11:70183737 C/G cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs9788333 0.962 rs34853044 chr13:21883784 C/T cg25811766 chr13:21894605 NA 0.28 5.38 0.44 3.53e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs12580194 0.593 rs59676560 chr12:55745425 T/C cg10672482 chr12:55725839 OR6C3 -0.52 -4.66 -0.39 8.13e-6 Cancer; TGCT cis rs7043114 0.507 rs7037075 chr9:95216613 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.37 -0.43 3.72e-7 Height; TGCT cis rs4654899 0.680 rs10916900 chr1:21239059 C/G cg01072550 chr1:21505969 NA -0.56 -9.17 -0.64 1.28e-15 Superior frontal gyrus grey matter volume; TGCT cis rs10894604 0.579 rs12275225 chr11:132652897 A/G cg16639665 chr11:133402497 OPCML 0.45 4.66 0.39 8.09e-6 Waist-hip ratio; TGCT cis rs1005277 0.505 rs1208689 chr10:38097775 C/G cg13531842 chr10:38383804 ZNF37A -0.39 -4.58 -0.38 1.1e-5 Extrinsic epigenetic age acceleration; TGCT cis rs1256061 0.528 rs10143616 chr14:64740175 G/A cg07667295 chr14:64320118 SYNE2 -0.49 -4.49 -0.37 1.63e-5 Hemoglobin concentration;Red blood cell count;Hematocrit; TGCT cis rs6430585 0.583 rs3754689 chr2:136590746 C/T cg07169764 chr2:136633963 MCM6 1.09 9.89 0.66 2.28e-17 Corneal structure; TGCT cis rs11718455 0.921 rs1404482 chr3:43997282 A/G cg08738300 chr3:44038990 NA 0.81 6.02 0.48 1.8e-8 Coronary artery disease; TGCT cis rs2239547 0.523 rs6803486 chr3:53098209 T/A cg10802521 chr3:52805072 NEK4 -0.58 -5.31 -0.43 4.87e-7 Schizophrenia; TGCT cis rs73099903 0.611 rs7485642 chr12:53391501 C/T cg24505307 chr12:53448429 TENC1 0.35 4.58 0.38 1.11e-5 Systolic blood pressure; TGCT cis rs910316 0.763 rs175047 chr14:75479039 C/G cg08847533 chr14:75593920 NEK9 -0.84 -9.16 -0.64 1.34e-15 Height; TGCT cis rs4665809 1.000 rs4665817 chr2:26305167 G/A cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs7586879 0.828 rs9631062 chr2:25110084 C/T cg01884057 chr2:25150051 NA 0.28 4.96 0.41 2.26e-6 Body mass index; TGCT cis rs3820068 0.553 rs7545782 chr1:15955227 G/C cg05660106 chr1:15850417 CASP9 0.84 8.28 0.6 1.64e-13 Systolic blood pressure; TGCT cis rs853679 0.607 rs201002 chr6:27808192 A/G cg10876282 chr6:28092338 ZSCAN16 0.72 4.48 0.37 1.65e-5 Depression; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg16697433 chr11:134398473 NA -0.92 -6.77 -0.52 4.48e-10 Follicular lymphoma; TGCT cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs769267 0.895 rs2916074 chr19:19530270 C/T cg03709012 chr19:19516395 GATAD2A 0.73 6.26 0.49 5.86e-9 Tonsillectomy; TGCT cis rs28595532 0.920 rs115103359 chr4:119739608 A/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs644799 0.544 rs1622515 chr11:95523433 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.56 6.01 0.48 1.91e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6840360 0.550 rs7675818 chr4:152690777 C/G cg17479576 chr4:152424074 FAM160A1 -0.53 -5.28 -0.43 5.53e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg08280861 chr8:58055591 NA 0.4 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs6582630 0.638 rs12423236 chr12:38548162 G/A cg26384229 chr12:38710491 ALG10B -0.53 -4.77 -0.39 5.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6952808 0.594 rs3778969 chr7:2139990 A/G cg04267008 chr7:1944627 MAD1L1 0.34 4.57 0.38 1.17e-5 Bipolar disorder and schizophrenia; TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg05215272 chr17:6899095 ALOX12 0.57 6.79 0.52 4.04e-10 Tonsillectomy; TGCT cis rs12477438 0.765 rs6750876 chr2:99679673 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs912057 0.671 rs1294420 chr6:6742752 C/T cg06612196 chr6:6737390 NA 0.47 7.06 0.54 1.05e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg13695892 chr22:41940480 POLR3H -0.9 -8.66 -0.61 2.17e-14 Vitiligo; TGCT cis rs778371 0.578 rs2675956 chr2:233753340 G/A cg25237894 chr2:233734115 C2orf82 -0.25 -4.49 -0.37 1.63e-5 Schizophrenia; TGCT cis rs910316 0.967 rs4899545 chr14:75568138 A/G cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT trans rs66573146 1.000 rs7675281 chr4:7002120 C/T cg07817883 chr1:32538562 TMEM39B 1.77 8.38 0.6 9.8e-14 Granulocyte percentage of myeloid white cells; TGCT cis rs1018836 0.828 rs756568 chr8:91557038 G/C cg16814680 chr8:91681699 NA -0.75 -7.83 -0.58 1.82e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6835098 1.000 rs6835098 chr4:174089238 T/C cg08422745 chr4:174089978 GALNT7 -0.95 -11.46 -0.72 3.51e-21 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs9457247 0.935 rs1044059 chr6:167369897 C/A cg23791538 chr6:167370224 RNASET2 0.51 4.98 0.41 2.05e-6 Crohn's disease; TGCT cis rs7312933 0.703 rs2406567 chr12:42551479 G/C cg19980929 chr12:42632907 YAF2 0.46 6.3 0.49 4.75e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2153535 0.580 rs7755284 chr6:8457479 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9814567 0.752 rs13098546 chr3:134333161 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.73 6.6 0.51 1.08e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs17221829 0.739 rs72971036 chr11:89370552 G/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg14893161 chr1:205819251 PM20D1 0.57 8.2 0.59 2.52e-13 Menarche (age at onset); TGCT cis rs854765 0.583 rs7214002 chr17:17852104 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.55 0.56 8.23e-12 Total body bone mineral density; TGCT cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg00814883 chr7:100076585 TSC22D4 -0.89 -9.24 -0.64 8.75e-16 Platelet count; TGCT cis rs9379774 0.623 rs6905021 chr6:25441831 C/G cg13320114 chr6:26216906 HIST1H2AE;HIST1H2BG 0.75 4.72 0.39 6.15e-6 Coronary artery disease; TGCT cis rs28830936 0.535 rs2289743 chr15:41860698 C/G cg17847044 chr15:42102381 MAPKBP1 -0.19 -4.57 -0.38 1.15e-5 Diastolic blood pressure; TGCT cis rs6582630 0.555 rs11182193 chr12:38474090 C/G cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4665809 1.000 rs3910272 chr2:26287842 T/A cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg08439880 chr3:133502540 NA -0.28 -5.15 -0.42 9.73e-7 Iron status biomarkers; TGCT cis rs12541335 0.692 rs2290274 chr8:22214374 C/T cg02788857 chr8:22132959 PIWIL2 0.3 5.44 0.44 2.7e-7 Hypertriglyceridemia; TGCT cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg17971929 chr21:40555470 PSMG1 -0.91 -8.09 -0.59 4.63e-13 Cognitive function; TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg22166914 chr1:53195759 ZYG11B 0.39 6.68 0.51 7.28e-10 Monocyte count; TGCT cis rs78456975 1.000 rs13416881 chr2:1554808 G/A cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs6089584 1.000 rs6089585 chr20:60564395 G/A cg06108461 chr20:60628389 TAF4 -0.53 -7.39 -0.55 1.9e-11 Body mass index; TGCT cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg16680214 chr1:154839983 KCNN3 -0.37 -7.77 -0.57 2.54e-12 Prostate cancer; TGCT cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.09 -0.42 1.27e-6 Bipolar disorder; TGCT cis rs926938 0.608 rs360612 chr1:115394747 G/A cg12756093 chr1:115239321 AMPD1 0.41 5.84 0.46 4.25e-8 Autism; TGCT cis rs7302981 0.934 rs7301649 chr12:50540870 T/C cg23855989 chr12:50355821 AQP5 -0.3 -4.5 -0.38 1.52e-5 Systolic blood pressure; TGCT cis rs7547997 0.685 rs11264963 chr1:158335533 A/G cg03528325 chr1:158223921 CD1A 0.33 4.69 0.39 7.06e-6 QRS duration; TGCT cis rs8067545 0.750 rs4570919 chr17:20000815 C/T cg13482628 chr17:19912719 NA 0.52 4.48 0.37 1.68e-5 Schizophrenia; TGCT trans rs6089829 0.889 rs6122348 chr20:61663921 C/T cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1555322 0.530 rs2425047 chr20:33871675 G/T cg03689076 chr20:33865952 NA -0.59 -4.46 -0.37 1.85e-5 Attention deficit hyperactivity disorder; TGCT cis rs7926906 1.000 rs7952309 chr11:90526114 A/G cg26138821 chr11:89956704 CHORDC1 -0.52 -5.46 -0.44 2.44e-7 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.783 rs318090 chr17:46991752 G/A cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs7772486 0.806 rs2247317 chr6:146217570 C/T cg23711669 chr6:146136114 FBXO30 0.83 9.16 0.64 1.32e-15 Lobe attachment (rater-scored or self-reported); TGCT trans rs1005277 0.522 rs1208767 chr10:38042295 G/T cg17830980 chr10:43048298 ZNF37B -0.64 -7.29 -0.55 3.24e-11 Extrinsic epigenetic age acceleration; TGCT trans rs7819412 0.538 rs4523214 chr8:10970773 T/A cg15556689 chr8:8085844 FLJ10661 -0.82 -8.13 -0.59 3.72e-13 Triglycerides; TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs877529 0.605 rs139387 chr22:39531085 G/A cg18708252 chr22:39545030 CBX7 -0.38 -5.6 -0.45 1.29e-7 Multiple myeloma; TGCT cis rs10791097 0.765 rs10894269 chr11:130722789 C/T cg14779329 chr11:130786720 SNX19 0.27 4.59 0.38 1.06e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7904368 0.806 rs7899923 chr10:16857394 G/A cg14835575 chr10:16859367 RSU1 0.7 7.5 0.56 1.04e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs7223966 1.000 rs9903897 chr17:61716705 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.76 0.39 5.24e-6 Hip circumference adjusted for BMI;Body mass index; TGCT trans rs829418 0.582 rs747662 chr1:21947218 C/G cg12068366 chr19:4548354 SEMA6B 0.61 6.7 0.52 6.47e-10 Neurocognitive impairment in HIV-1 infection (continuous); TGCT cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg23719950 chr11:63933701 MACROD1 -0.72 -5.95 -0.47 2.61e-8 Mean platelet volume; TGCT cis rs2688608 0.592 rs7076585 chr10:75503692 T/C cg15838173 chr10:75533400 FUT11 -0.31 -4.89 -0.4 3.12e-6 Inflammatory bowel disease; TGCT cis rs2840044 1.000 rs10068 chr17:33901965 C/G cg05299278 chr17:33885742 SLFN14 -0.24 -5.26 -0.43 6.14e-7 Response to radiotherapy in cancer (late toxicity); TGCT cis rs3749237 0.964 rs11717463 chr3:49808981 C/T cg07636037 chr3:49044803 WDR6 0.55 4.49 0.37 1.58e-5 Resting heart rate; TGCT cis rs9818758 0.607 rs73082362 chr3:49113729 C/T cg00383909 chr3:49044727 WDR6 1.54 5.91 0.47 3.14e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2760061 0.626 rs592736 chr1:228116831 A/G cg02753203 chr1:228287806 NA -0.33 -6.25 -0.49 6e-9 Diastolic blood pressure; TGCT cis rs6750047 0.566 rs1157185 chr2:38285735 C/T cg07380506 chr2:38303506 CYP1B1 0.67 6.15 0.48 9.81e-9 Cutaneous malignant melanoma;Melanoma; TGCT cis rs3772130 0.564 rs28760466 chr3:121601510 A/G cg20356878 chr3:121714668 ILDR1 0.38 4.85 0.4 3.59e-6 Cognitive performance; TGCT cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs12367572 1.000 rs10880704 chr12:45318430 C/T cg04608330 chr12:45269318 NELL2 -0.68 -7.2 -0.54 5e-11 Gut microbiome composition (summer); TGCT cis rs263156 0.903 rs263130 chr6:142928295 A/G cg18419694 chr6:143832440 FUCA2 0.43 4.97 0.41 2.16e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs9807989 0.507 rs2160201 chr2:103033961 T/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs992157 0.737 rs3731860 chr2:219156979 G/A cg00012203 chr2:219082015 ARPC2 -0.82 -8.15 -0.59 3.39e-13 Colorectal cancer; TGCT cis rs9457247 0.967 rs443570 chr6:167389925 G/A cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg07424592 chr7:64974309 NA 1.22 7.35 0.55 2.29e-11 Diabetic kidney disease; TGCT cis rs7607369 0.679 rs6751527 chr2:219630965 C/G cg02176678 chr2:219576539 TTLL4 0.48 6.36 0.5 3.6e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs9807989 0.801 rs11123925 chr2:102977511 G/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs9399401 0.667 rs6900233 chr6:142717283 C/G cg03128060 chr6:142623767 GPR126 0.37 4.47 0.37 1.77e-5 Chronic obstructive pulmonary disease; TGCT cis rs9926296 0.546 rs9935541 chr16:89905925 G/C cg26513180 chr16:89883248 FANCA 0.78 7.68 0.57 4.06e-12 Vitiligo; TGCT cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs854765 0.547 rs2955380 chr17:17944349 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.29 -0.6 1.59e-13 Total body bone mineral density; TGCT cis rs6141769 0.518 rs2377665 chr20:31309054 T/C cg13636640 chr20:31349939 DNMT3B -0.51 -4.48 -0.37 1.68e-5 Subjective well-being; TGCT cis rs11578119 0.933 rs12119012 chr1:170446678 C/T cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs3749237 0.595 rs1464567 chr3:49459252 C/G cg07636037 chr3:49044803 WDR6 -0.64 -6.02 -0.48 1.83e-8 Resting heart rate; TGCT cis rs228437 0.507 rs228439 chr6:134898523 C/T cg09872934 chr6:134495829 SGK1 0.49 4.44 0.37 1.99e-5 Melanoma; TGCT cis rs752010 0.619 rs1123483 chr1:42114198 C/T cg06885757 chr1:42089581 HIVEP3 -0.29 -5.1 -0.42 1.26e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs9906944 0.898 rs9909861 chr17:47079416 C/A cg20966754 chr17:47091339 IGF2BP1 -0.43 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs12477438 0.765 rs2309454 chr2:99595418 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs8051431 0.876 rs4788453 chr16:72020727 A/G cg06353428 chr16:71660113 MARVELD3 0.6 4.65 0.39 8.53e-6 LDL cholesterol levels; TGCT cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg10117171 chr1:25599238 RHD -0.34 -5.48 -0.44 2.31e-7 Erythrocyte sedimentation rate; TGCT cis rs1156327 0.510 rs179223 chr16:19317148 G/T cg27311092 chr16:19142612 NA 0.49 4.47 0.37 1.74e-5 Periodontal disease-related phenotypes; TGCT cis rs1008375 0.932 rs12500912 chr4:17603318 C/T cg10189774 chr4:17578691 LAP3 0.67 5.69 0.45 8.77e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9915657 0.870 rs4140903 chr17:70133771 C/T cg06234051 chr17:70120541 SOX9 -0.23 -4.61 -0.38 9.78e-6 Thyroid hormone levels; TGCT cis rs4689388 0.890 rs3821941 chr4:6286954 A/G cg14416269 chr4:6271139 WFS1 0.39 5.19 0.42 8.22e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6435862 0.500 rs12477063 chr2:215673664 C/T cg04004882 chr2:215674386 BARD1 -0.73 -6.51 -0.5 1.71e-9 Neuroblastoma (high-risk); TGCT cis rs4713118 0.662 rs175954 chr6:28011585 A/G cg18675097 chr6:28227127 NKAPL -0.36 -4.54 -0.38 1.31e-5 Parkinson's disease; TGCT cis rs682748 0.840 rs297177 chr5:17114476 C/T cg23987134 chr5:17158319 LOC285696 -0.2 -4.76 -0.39 5.33e-6 Hippocampal atrophy; TGCT cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg06634786 chr22:41940651 POLR3H -0.86 -8.32 -0.6 1.34e-13 Vitiligo; TGCT cis rs597539 0.652 rs592697 chr11:68650064 G/A cg06028808 chr11:68637592 NA 0.51 6.54 0.51 1.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2013441 1.000 rs9904928 chr17:20180536 C/T cg23224458 chr17:20280056 CCDC144C 0.39 4.65 0.39 8.34e-6 Obesity-related traits; TGCT cis rs12908161 0.959 rs12908699 chr15:85240403 G/T cg11189052 chr15:85197271 WDR73 0.75 6.3 0.49 4.8e-9 Schizophrenia; TGCT cis rs56235845 0.694 rs4976643 chr5:176760227 A/C cg16006841 chr5:176797999 RGS14 0.5 7.45 0.56 1.38e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs1729951 0.575 rs16844362 chr3:136704008 T/C cg12473912 chr3:136751656 NA 0.39 6.18 0.48 8.68e-9 Neuroticism; TGCT cis rs9611565 0.568 rs5751159 chr22:42175365 G/A cg06634786 chr22:41940651 POLR3H 0.78 7.31 0.55 2.85e-11 Vitiligo; TGCT cis rs73198271 0.960 rs17154702 chr8:8609880 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.91 -0.4 2.79e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1218582 0.772 rs1109815 chr1:154909268 A/G cg09359103 chr1:154839909 KCNN3 -0.64 -11.69 -0.72 9.69e-22 Prostate cancer; TGCT cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.15 0.54 6.5500000000000006e-11 Platelet count; TGCT trans rs4650994 0.544 rs10798613 chr1:178500022 C/T cg05059571 chr16:84539110 KIAA1609 -0.54 -11.12 -0.71 2.39e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9640161 0.830 rs76741564 chr7:150059529 A/T cg10018233 chr7:150070692 REPIN1 0.31 4.54 0.38 1.3e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs829883 0.714 rs249847 chr12:98867716 C/T cg25150519 chr12:98850993 NA 0.63 7.62 0.56 5.78e-12 Colorectal adenoma (advanced); TGCT trans rs11722228 0.522 rs1109472 chr4:10134448 C/G cg26043149 chr18:55253948 FECH 1.27 12.85 0.76 1.54e-24 Gout;Urate levels;Serum uric acid levels; TGCT cis rs9790314 1.000 rs4370045 chr3:160943865 A/G cg03342759 chr3:160939853 NMD3 -0.42 -4.44 -0.37 1.94e-5 Morning vs. evening chronotype; TGCT cis rs6964587 0.597 rs975707 chr7:91874527 C/G cg17063962 chr7:91808500 NA 0.7 6.65 0.51 8.27e-10 Breast cancer; TGCT cis rs514406 0.679 rs11206006 chr1:53218380 A/G cg27535305 chr1:53392650 SCP2 0.26 5.04 0.41 1.57e-6 Monocyte count; TGCT cis rs9325144 0.647 rs12227834 chr12:38849246 G/C cg26384229 chr12:38710491 ALG10B -0.6 -5.47 -0.44 2.33e-7 Morning vs. evening chronotype; TGCT cis rs2070433 0.539 rs2839312 chr21:47958225 T/C cg12379764 chr21:47803548 PCNT 0.53 5.38 0.43 3.6e-7 Lymphocyte counts; TGCT cis rs7666738 0.791 rs1593571 chr4:98963763 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg16145915 chr7:1198662 ZFAND2A -0.6 -8.51 -0.61 4.69e-14 Longevity;Endometriosis; TGCT cis rs2797160 0.684 rs1832937 chr6:125985934 A/G cg05901451 chr6:126070800 HEY2 0.79 7.35 0.55 2.34e-11 Endometrial cancer; TGCT cis rs2797160 0.967 rs2747718 chr6:126009109 C/A cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs17270561 0.562 rs74293932 chr6:26014811 C/A cg17042849 chr6:26104293 HIST1H4C -0.81 -5.71 -0.46 7.76e-8 Iron status biomarkers; TGCT cis rs72615157 0.645 rs76281814 chr7:99846414 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.65 -5.2 -0.42 8.01e-7 Lung function (FEV1/FVC); TGCT cis rs2742417 0.624 rs2673030 chr3:45757900 T/G cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs17221829 0.626 rs2931188 chr11:89355428 A/T cg02982614 chr11:89391479 FOLH1B -0.28 -4.82 -0.4 4.1e-6 Anxiety in major depressive disorder; TGCT cis rs7833790 0.927 rs61020899 chr8:82757090 C/T cg17211192 chr8:82754475 SNX16 1.06 8.63 0.61 2.54e-14 Diastolic blood pressure; TGCT cis rs9303401 0.659 rs34170300 chr17:56789905 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs6964587 0.620 rs7808587 chr7:91620096 G/A cg17063962 chr7:91808500 NA 0.75 7.1 0.54 8.68e-11 Breast cancer; TGCT cis rs10197940 0.662 rs10173699 chr2:152281561 C/G cg19508488 chr2:152266495 RIF1 -0.72 -6.45 -0.5 2.23e-9 Lung cancer; TGCT cis rs7772486 0.875 rs9403765 chr6:146368041 C/T cg23711669 chr6:146136114 FBXO30 -0.82 -8.87 -0.62 6.75e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs1949733 0.958 rs2631731 chr4:8429817 A/G cg13073564 chr4:8508604 NA -0.47 -4.97 -0.41 2.15e-6 Response to antineoplastic agents; TGCT cis rs12477438 0.501 rs6753063 chr2:99801469 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs17539620 0.624 rs62432737 chr6:154834772 G/A cg20019720 chr6:154832845 CNKSR3 0.57 4.99 0.41 2.02e-6 Lipoprotein (a) levels; TGCT cis rs4727027 0.866 rs10435245 chr7:148816081 C/G cg23583168 chr7:148888333 NA -0.72 -9.17 -0.64 1.3e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs11030122 0.632 rs10835556 chr11:4083013 A/G cg18678763 chr11:4115507 RRM1 -0.48 -5.87 -0.47 3.66e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs7589728 0.563 rs75606549 chr2:88466069 T/C cg04511125 chr2:88470314 THNSL2 0.83 6.93 0.53 2e-10 Plasma clusterin levels; TGCT cis rs9435341 0.965 rs1335053 chr1:107622823 C/T cg09367891 chr1:107599246 PRMT6 -0.62 -5.24 -0.43 6.6e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs76878669 0.561 rs4930177 chr11:66120784 T/C cg18002602 chr11:66138449 SLC29A2 0.54 6.62 0.51 9.76e-10 Educational attainment (years of education); TGCT trans rs10203711 1.000 rs907112 chr2:239566603 C/G cg16021909 chr1:248021091 TRIM58 -0.67 -6.77 -0.52 4.51e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.505 rs437954 chr1:53173321 C/G cg16325326 chr1:53192061 ZYG11B 0.86 12.13 0.74 8.27e-23 Monocyte count; TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg26338869 chr17:61819248 STRADA -0.58 -5.24 -0.43 6.59e-7 Prudent dietary pattern; TGCT cis rs62344088 0.590 rs73016639 chr5:172465 C/T cg10601043 chr5:1076365 SLC12A7 0.58 4.74 0.39 5.71e-6 Asthma (childhood onset); TGCT cis rs7781977 0.554 rs7789913 chr7:50352695 C/T cg01139861 chr7:50343298 IKZF1 0.49 5.72 0.46 7.46e-8 IgG glycosylation; TGCT cis rs9303401 0.659 rs35564417 chr17:56718286 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs74233809 0.636 rs284851 chr10:104578531 C/G cg05855489 chr10:104503620 C10orf26 0.71 4.82 0.4 4.13e-6 Birth weight; TGCT cis rs1629083 0.846 rs1806 chr11:118076004 C/T cg16594165 chr11:118135105 MPZL2 -0.32 -4.45 -0.37 1.88e-5 Lung cancer; TGCT cis rs7523273 0.606 rs2796263 chr1:207915978 T/C cg22525895 chr1:207977042 MIR29B2 0.54 8.77 0.62 1.16e-14 Schizophrenia; TGCT cis rs11792861 0.816 rs11788336 chr9:111688387 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.54 5.13 0.42 1.07e-6 Menarche (age at onset); TGCT cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs4595586 0.545 rs12820138 chr12:39357049 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs3782455 1.000 rs116855053 chr12:114403055 C/T cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs921968 0.541 rs733925 chr2:219302466 G/A cg02176678 chr2:219576539 TTLL4 -0.47 -6.71 -0.52 6.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs589448 0.535 rs12423794 chr12:69713018 G/A cg20891283 chr12:69753455 YEATS4 0.72 7.48 0.56 1.17e-11 Cerebrospinal fluid biomarker levels; TGCT cis rs7584330 0.554 rs76980036 chr2:238426750 G/A cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs1568889 1.000 rs12790932 chr11:28046189 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 7.88 0.58 1.45e-12 Bipolar disorder; TGCT cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg06634786 chr22:41940651 POLR3H 0.69 6.54 0.51 1.45e-9 Vitiligo; TGCT cis rs7662987 0.517 rs3018047 chr4:100014510 C/T cg12011299 chr4:100065546 ADH4 -0.41 -4.96 -0.41 2.26e-6 Smoking initiation; TGCT cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg06238570 chr21:40685208 BRWD1 0.68 6.36 0.5 3.5e-9 Cognitive function; TGCT cis rs6597981 0.592 rs10902218 chr11:743813 C/T cg01741372 chr11:783889 NA -0.38 -4.81 -0.4 4.31e-6 Breast cancer; TGCT cis rs6975373 0.730 rs1009528 chr7:4456304 G/T cg10785373 chr7:4456119 NA -0.55 -6.27 -0.49 5.5e-9 Borderline personality disorder; TGCT trans rs9951602 0.512 rs12607561 chr18:76644284 G/A cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs904251 1.000 rs12212090 chr6:37431808 A/G cg25019722 chr6:37503610 NA -0.47 -6.26 -0.49 5.69e-9 Cognitive performance; TGCT cis rs9926296 0.681 rs12923946 chr16:89821080 C/T cg27121462 chr16:89883253 FANCA 0.57 5.28 0.43 5.69e-7 Vitiligo; TGCT cis rs2033711 0.905 rs1077420 chr19:58968875 A/C cg03735888 chr19:58951602 ZNF132 0.53 4.71 0.39 6.41e-6 Uric acid clearance; TGCT cis rs3847687 0.869 rs11061300 chr12:131523261 G/A cg25772418 chr12:131519998 GPR133 -0.3 -4.77 -0.39 5e-6 Longevity; TGCT cis rs1729951 0.575 rs1682357 chr3:136692009 G/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs17376456 0.877 rs9314095 chr5:93425495 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs208520 1.000 rs12190773 chr6:66968194 T/C cg07460842 chr6:66804631 NA 0.83 7.52 0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs3741151 1.000 rs74749711 chr11:73052839 A/T cg17517138 chr11:73019481 ARHGEF17 1.03 5.19 0.42 8.31e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs1205863 0.607 rs1210621 chr6:11927921 A/G cg07106625 chr6:11870215 NA 0.47 4.72 0.39 6.18e-6 Disc degeneration (lumbar); TGCT trans rs916888 0.773 rs199457 chr17:44795469 C/T cg01341218 chr17:43662625 NA 1.09 8.66 0.61 2.15e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1008375 0.898 rs7678654 chr4:17575376 T/G cg10189774 chr4:17578691 LAP3 0.63 5.53 0.44 1.84e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28595532 0.920 rs115226628 chr4:119639818 A/G cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT cis rs1552244 0.700 rs9833566 chr3:9981671 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 5.89 0.47 3.37e-8 Alzheimer's disease; TGCT cis rs67072384 0.818 rs1872128 chr11:72465526 C/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.68 -0.39 7.3e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs4972806 0.814 rs4246626 chr2:177046430 A/C cg13092806 chr2:177043255 NA 0.56 5.03 0.41 1.66e-6 IgG glycosylation; TGCT cis rs4273100 0.646 rs1472932 chr17:19220666 C/T cg03910582 chr17:19030146 GRAPL -0.49 -6.15 -0.48 9.9e-9 Schizophrenia; TGCT cis rs6684514 0.961 rs10908501 chr1:156285513 G/T cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9291683 0.632 rs11734375 chr4:10046298 A/G cg00071950 chr4:10020882 SLC2A9 0.68 8.74 0.62 1.38e-14 Bone mineral density; TGCT cis rs9858542 0.537 rs9818758 chr3:49382925 G/A cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.59 0.38 1.08e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs17826219 0.706 rs61643715 chr17:29057762 A/G cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Body mass index; TGCT cis rs17376456 0.569 rs7713956 chr5:93133185 T/C cg25358565 chr5:93447407 FAM172A -0.76 -6.72 -0.52 5.94e-10 Diabetic retinopathy; TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg25767906 chr1:53392781 SCP2 -0.63 -7.64 -0.57 5e-12 Monocyte count; TGCT cis rs7918232 0.941 rs1753413 chr10:27397112 T/C cg14442939 chr10:27389572 ANKRD26 0.71 5.33 0.43 4.45e-7 Breast cancer; TGCT cis rs7429990 0.932 rs12493348 chr3:48143538 A/T cg11946769 chr3:48343235 NME6 -0.57 -4.77 -0.39 5.14e-6 Educational attainment (years of education); TGCT cis rs3784262 0.565 rs8041644 chr15:58266833 C/T cg12031962 chr15:58353849 ALDH1A2 -0.37 -5.23 -0.43 6.89e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs35000415 0.515 rs35518304 chr7:128732319 C/T cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.7 -0.39 6.77e-6 Systemic lupus erythematosus; TGCT cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg13695892 chr22:41940480 POLR3H -0.87 -8.01 -0.58 6.94e-13 Vitiligo; TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs6570726 0.643 rs9403735 chr6:145936591 C/T cg05347473 chr6:146136440 FBXO30 0.53 4.96 0.41 2.29e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs73198271 0.595 rs11780672 chr8:8584153 A/C ch.8.214553F chr8:8189620 PRAGMIN -0.3 -4.85 -0.4 3.56e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9902453 0.933 rs7216494 chr17:28502651 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs61774743 0.754 rs11581271 chr1:41835061 C/G cg01193554 chr1:41846683 NA -0.42 -5.3 -0.43 5.12e-7 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.864 rs7431857 chr3:48900347 G/A cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg11003573 chr3:44754125 ZNF502 -0.41 -4.69 -0.39 7.19e-6 Depressive symptoms; TGCT cis rs4727027 0.901 rs4727019 chr7:148822266 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6121246 0.821 rs6058448 chr20:30332396 C/T cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7302981 0.967 rs11831413 chr12:50550383 A/T cg23855989 chr12:50355821 AQP5 0.3 4.5 0.38 1.52e-5 Systolic blood pressure; TGCT cis rs60843830 1.000 rs58461606 chr2:267367 G/T cg00108164 chr2:264199 ACP1;SH3YL1 0.7 6.66 0.51 7.99e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7424096 0.793 rs17497197 chr2:37162975 T/C cg14987922 chr2:37194071 STRN 0.58 4.75 0.39 5.53e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs4733781 1.000 rs12680942 chr8:131264033 A/G cg16277922 chr8:131349729 ASAP1 0.43 5.48 0.44 2.31e-7 Tuberculosis; TGCT cis rs6988636 1.000 rs13261066 chr8:124190276 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs7044106 0.762 rs7357638 chr9:123389204 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.93 0.4 2.59e-6 Hip circumference adjusted for BMI; TGCT cis rs4746818 1.000 rs906218 chr10:70960913 C/T cg04149295 chr10:70884716 VPS26A 0.76 4.97 0.41 2.19e-6 Left atrial antero-posterior diameter; TGCT cis rs17767294 0.803 rs59701161 chr6:27646117 T/C cg08851530 chr6:28072375 NA 1.43 6.96 0.53 1.73e-10 Parkinson's disease; TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs13177918 0.677 rs13161099 chr5:149822362 G/A cg14059543 chr5:149831962 NA -0.72 -9.49 -0.65 2.17e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs12681288 0.823 rs2701903 chr8:1004029 A/G cg04851639 chr8:1020857 NA 0.36 6.47 0.5 2.01e-9 Schizophrenia; TGCT cis rs753778 0.667 rs10103731 chr8:142206068 C/T cg18755752 chr8:142205143 DENND3 -0.25 -4.59 -0.38 1.06e-5 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs66573146 0.808 rs73202120 chr4:7005588 A/G cg05069807 chr4:6945702 TBC1D14 0.3 4.87 0.4 3.26e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs12681287 0.752 rs10435564 chr8:87266239 T/C cg27223183 chr8:87520930 FAM82B -0.81 -5.66 -0.45 9.9e-8 Caudate activity during reward; TGCT cis rs72781680 0.846 rs72780108 chr2:23986780 G/A cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs597539 0.652 rs674654 chr11:68698762 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 7.43 0.55 1.56e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs739496 0.947 rs2283358 chr12:111865565 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT trans rs9951602 0.573 rs78623099 chr18:76646228 G/T cg02800362 chr5:177631904 HNRNPAB 1.14 13.02 0.76 6.04e-25 Obesity-related traits; TGCT cis rs968451 1.000 rs17000962 chr22:39680187 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.89 7.9 0.58 1.28e-12 Primary biliary cholangitis; TGCT cis rs7666738 0.830 rs1869897 chr4:98730997 C/T cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7949030 0.688 rs2849031 chr11:62365665 G/A cg11742103 chr11:62369870 EML3;MTA2 -0.6 -8.74 -0.62 1.39e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8072100 0.701 rs4794053 chr17:45769551 G/A cg08085267 chr17:45401833 C17orf57 -0.43 -4.82 -0.4 4.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7937682 0.575 rs7127010 chr11:111770782 C/T cg09085632 chr11:111637200 PPP2R1B 0.91 8.56 0.61 3.6e-14 Primary sclerosing cholangitis; TGCT cis rs2486288 0.656 rs11631021 chr15:45556829 A/G cg14582100 chr15:45693742 SPATA5L1 -0.42 -4.92 -0.4 2.7e-6 Glomerular filtration rate; TGCT cis rs4253772 0.550 rs6007761 chr22:46670394 C/T cg09491104 chr22:46646882 C22orf40 0.63 6.84 0.52 3.23e-10 LDL cholesterol;Cholesterol, total; TGCT cis rs5769707 0.681 rs9616329 chr22:50026314 G/A cg05373962 chr22:49881684 NA -0.31 -5.3 -0.43 5.1e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg05985448 chr10:134359359 INPP5A 0.23 4.99 0.41 2.01e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs826838 0.967 rs73096706 chr12:38860563 G/A cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs7209700 0.778 rs3851807 chr17:45351519 C/G cg21624342 chr17:45890973 OSBPL7 0.16 4.44 0.37 1.97e-5 IgG glycosylation; TGCT trans rs7819412 0.807 rs9657519 chr8:10945439 A/G cg15556689 chr8:8085844 FLJ10661 -0.88 -8.75 -0.62 1.29e-14 Triglycerides; TGCT cis rs12049351 0.665 rs4148761 chr1:229662344 C/T cg12130225 chr1:229698885 NA 0.38 4.63 0.38 8.95e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs79349575 0.783 rs4793995 chr17:47019399 A/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs422249 0.512 rs174574 chr11:61600342 A/C cg19610905 chr11:61596333 FADS2 0.96 9.66 0.66 8.51e-17 Trans fatty acid levels; TGCT cis rs96067 0.711 rs11263861 chr1:36628033 G/A cg07093915 chr1:36184400 C1orf216 -0.46 -4.55 -0.38 1.24e-5 Corneal structure; TGCT cis rs9894429 0.789 rs7219915 chr17:79591813 C/T cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT cis rs35146811 0.625 rs858514 chr7:99825748 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs9341808 0.500 rs2322629 chr6:80811540 C/T cg08355045 chr6:80787529 NA 0.33 5.37 0.43 3.8e-7 Sitting height ratio; TGCT cis rs3733606 0.775 rs66514314 chr4:6827238 C/T cg25793812 chr4:6677191 LOC93622 0.39 4.85 0.4 3.68e-6 Platelet count; TGCT cis rs546131 0.642 rs579926 chr11:34853155 C/T cg06937548 chr11:34938143 PDHX;APIP 0.52 4.55 0.38 1.24e-5 Lung disease severity in cystic fibrosis; TGCT cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg23708337 chr7:1209742 NA 0.51 4.51 0.38 1.49e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6570726 0.791 rs9373464 chr6:145907167 T/C cg23711669 chr6:146136114 FBXO30 0.85 9.24 0.64 8.9e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1997103 1.000 rs1997102 chr7:55399322 A/C cg17469321 chr7:55412551 NA -0.59 -6.08 -0.48 1.39e-8 QRS interval (sulfonylurea treatment interaction); TGCT cis rs3858526 0.959 rs61876223 chr11:5943393 G/A cg05234568 chr11:5960015 NA -0.47 -4.66 -0.39 8.11e-6 DNA methylation (variation); TGCT cis rs4819052 0.851 rs7275874 chr21:46671223 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10779751 0.922 rs2746637 chr1:11275588 A/G cg08854313 chr1:11322531 MTOR 0.94 8.51 0.61 4.75e-14 Body mass index; TGCT cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg03264133 chr6:25882463 NA -1.07 -14.31 -0.79 5.01e-28 Urate levels; TGCT cis rs7551222 0.716 rs6679311 chr1:204559676 T/C cg09150239 chr1:204347429 NA 0.49 4.55 0.38 1.24e-5 Schizophrenia; TGCT cis rs9357506 1.000 rs62402364 chr6:46313913 T/C cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs9362426 0.708 rs6907825 chr6:88102822 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.42 4.66 0.39 8.11e-6 Depressive episodes in bipolar disorder; TGCT cis rs6964587 1.000 rs417 chr7:91581121 C/A cg17063962 chr7:91808500 NA -0.91 -10.02 -0.67 1.13e-17 Breast cancer; TGCT cis rs1008375 1.000 rs6449319 chr4:17640283 T/A cg16339924 chr4:17578868 LAP3 0.7 5.72 0.46 7.7e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6912958 0.630 rs4707377 chr6:88280332 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs28595532 0.920 rs114670456 chr4:119771202 A/G cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs2657888 0.593 rs2638319 chr12:56857057 A/G cg23002907 chr12:56915593 RBMS2 -0.45 -6.08 -0.48 1.37e-8 Adiponectin levels; TGCT trans rs8073060 0.586 rs225291 chr17:33927126 A/G cg19694781 chr19:47549865 TMEM160 -0.51 -11.27 -0.71 9.98e-21 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2075371 0.501 rs1646652 chr7:134024515 A/T cg11752832 chr7:134001865 SLC35B4 0.59 5.1 0.42 1.25e-6 Mean platelet volume; TGCT cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2980439 0.517 rs793753 chr8:8105359 T/G cg06636001 chr8:8085503 FLJ10661 -0.61 -5.4 -0.44 3.24e-7 Neuroticism; TGCT cis rs7659604 0.540 rs7676867 chr4:122671315 T/C cg19748678 chr4:122722346 EXOSC9 -0.51 -4.93 -0.4 2.61e-6 Type 2 diabetes; TGCT cis rs6088590 1.000 rs3787222 chr20:33333040 T/A cg24642439 chr20:33292090 TP53INP2 0.69 6.19 0.49 8.14e-9 Coronary artery disease; TGCT cis rs6424115 0.830 rs2502995 chr1:24199290 T/C cg15997130 chr1:24165203 NA 0.86 9.44 0.65 2.86e-16 Immature fraction of reticulocytes; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg11905131 chr22:24372483 LOC391322 -0.98 -11.56 -0.72 2.04e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7267979 0.966 rs2387882 chr20:25378802 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9527 0.590 rs7092029 chr10:104823909 A/T cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT trans rs1814175 0.715 rs10839409 chr11:49884647 G/T cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs9894429 0.789 rs7213849 chr17:79567610 C/T cg18240062 chr17:79603768 NPLOC4 -0.84 -9.67 -0.66 8.03e-17 Eye color traits; TGCT cis rs6978712 1.000 rs75306531 chr7:127151869 A/T cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs933688 1.000 rs1964292 chr5:90743608 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 8.8 0.62 9.68e-15 Smoking behavior; TGCT cis rs79349575 0.783 rs12453394 chr17:46994970 G/A cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs526231 0.547 rs72783895 chr5:102287496 C/A cg23492399 chr5:102201601 PAM -0.52 -4.52 -0.38 1.41e-5 Primary biliary cholangitis; TGCT cis rs9296092 0.538 rs9461879 chr6:33516907 C/T cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.25e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg06873352 chr17:61820015 STRADA 0.57 6.21 0.49 7.34e-9 Prudent dietary pattern; TGCT cis rs28595532 0.920 rs115484560 chr4:119756781 T/G cg21605333 chr4:119757512 SEC24D 1.62 7.73 0.57 3.22e-12 Cannabis dependence symptom count; TGCT cis rs71597109 0.639 rs17266552 chr4:102726519 G/A cg14855874 chr4:102712397 BANK1 0.41 4.7 0.39 6.66e-6 Chronic lymphocytic leukemia; TGCT cis rs6598955 0.670 rs10794525 chr1:26537193 C/A cg01614726 chr1:26633154 UBXN11 0.49 4.69 0.39 7.09e-6 Obesity-related traits; TGCT cis rs9436747 0.630 rs12405556 chr1:66063117 G/T cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.52 0.38 1.42e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT trans rs1005277 0.602 rs1780141 chr10:38504299 T/C cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs3824867 0.920 rs3740684 chr11:47468820 C/T cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs12711979 0.509 rs10191674 chr2:3827891 C/T cg17052675 chr2:3827356 NA -0.56 -13.3 -0.77 1.28e-25 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs763121 0.853 rs5757200 chr22:39043491 T/G cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs514406 0.825 rs6695819 chr1:53223366 T/C cg25767906 chr1:53392781 SCP2 0.48 5.56 0.45 1.57e-7 Monocyte count; TGCT cis rs79349575 0.783 rs9912829 chr17:46982749 G/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs9398235 0.929 rs4945861 chr6:110728429 C/T cg19196401 chr6:110721138 DDO 0.5 4.76 0.39 5.28e-6 Systemic lupus erythematosus; TGCT cis rs1723838 0.510 rs2471904 chr11:73690599 G/A cg26954736 chr11:73693896 UCP2 -1.41 -6.25 -0.49 5.93e-9 Obesity-related traits; TGCT cis rs854765 0.618 rs8066982 chr17:17851377 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.85 0.58 1.65e-12 Total body bone mineral density; TGCT cis rs11601602 0.576 rs12576396 chr11:28555952 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.67 5.74 0.46 6.71e-8 Obesity-related traits; TGCT cis rs4237845 0.773 rs6650217 chr12:58289072 T/G cg02175503 chr12:58329896 NA 0.52 5.49 0.44 2.17e-7 Intelligence (multi-trait analysis); TGCT cis rs111803315 0.661 rs113008598 chr14:60002312 C/T cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs1218582 0.772 rs6656435 chr1:154876869 G/A cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs4911259 0.552 rs13042651 chr20:31467423 C/T cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs11112613 0.713 rs871220 chr12:105938558 G/A cg03607813 chr12:105948248 NA 0.46 5.35 0.43 4.14e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs425277 0.606 rs451061 chr1:2075068 C/G cg24578937 chr1:2090814 PRKCZ 0.24 6.16 0.48 9.35e-9 Height; TGCT cis rs10751667 0.961 rs6421967 chr11:983966 T/C cg06064525 chr11:970664 AP2A2 -0.31 -5.78 -0.46 5.58e-8 Alzheimer's disease (late onset); TGCT cis rs2050392 0.799 rs303429 chr10:30708441 C/T cg13289132 chr10:30722225 MAP3K8 -0.38 -4.58 -0.38 1.12e-5 Inflammatory bowel disease; TGCT cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs2742417 1.000 rs2742417 chr3:45731451 C/T cg04837898 chr3:45731254 SACM1L -0.53 -5.44 -0.44 2.76e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs4253311 0.520 rs10000459 chr4:187124459 A/C cg19358738 chr4:186734530 SORBS2 0.17 4.49 0.37 1.6e-5 Plasma renin activity levels;Circulating chromogranin peptide levels;Blood metabolite levels; TGCT cis rs12620999 1.000 rs11689249 chr2:238083542 T/A cg23555395 chr2:238036564 NA -0.29 -4.99 -0.41 1.95e-6 Systemic lupus erythematosus; TGCT cis rs903263 0.601 rs6669045 chr1:84560735 A/T cg09664975 chr1:84543551 PRKACB 0.5 4.87 0.4 3.36e-6 Breast cancer (male); TGCT cis rs6893807 0.778 rs13162708 chr5:87943345 C/T cg24804195 chr5:87968844 LOC645323 0.78 4.53 0.38 1.39e-5 Body mass index; TGCT cis rs10256972 0.630 rs10282584 chr7:1081442 C/T cg00431813 chr7:1051703 C7orf50 -0.3 -6.76 -0.52 4.92e-10 Longevity;Endometriosis; TGCT cis rs12134245 0.776 rs12137878 chr1:91973210 G/T cg25838465 chr1:92012736 NA -0.44 -7.0 -0.53 1.41e-10 Breast cancer; TGCT cis rs7772486 0.790 rs10223507 chr6:146285204 C/A cg05347473 chr6:146136440 FBXO30 -0.53 -5.18 -0.42 8.75e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.88 9.32 0.64 5.46e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg25767906 chr1:53392781 SCP2 0.47 5.26 0.43 6e-7 Monocyte count; TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg22235522 chr6:17169462 NA 0.64 4.63 0.38 9.07e-6 Gambling; TGCT cis rs9914544 1.000 rs67411574 chr17:18797337 A/G cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.41 1.36e-6 Educational attainment (years of education); TGCT cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs739401 0.572 rs389128 chr11:3083873 G/T cg25174290 chr11:3078921 CARS 0.53 5.18 0.42 8.8e-7 Longevity; TGCT cis rs9467711 0.745 rs9467714 chr6:26340785 C/T cg26531700 chr6:26746687 NA -1.05 -5.26 -0.43 6.14e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11671005 0.693 rs34230465 chr19:58943576 C/G cg13877915 chr19:58951672 ZNF132 0.63 5.0 0.41 1.95e-6 Mean platelet volume; TGCT cis rs4746818 0.901 rs4746816 chr10:70874866 G/T cg04149295 chr10:70884716 VPS26A 0.76 4.48 0.37 1.69e-5 Left atrial antero-posterior diameter; TGCT cis rs6671200 0.573 rs6666528 chr1:95697490 C/A cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs2439831 0.850 rs7169322 chr15:44131014 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs614226 1.000 rs616157 chr12:120925795 T/C cg01236616 chr12:121019343 POP5 -1.22 -12.32 -0.74 2.86e-23 Type 1 diabetes nephropathy; TGCT trans rs8073060 0.586 rs225257 chr17:33956625 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2836974 0.644 rs2836982 chr21:40689171 C/A cg11890956 chr21:40555474 PSMG1 -0.75 -6.81 -0.52 3.82e-10 Cognitive function; TGCT cis rs7120118 0.517 rs11530168 chr11:47322986 A/G cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.26e-7 HDL cholesterol; TGCT cis rs13256369 1.000 rs873063 chr8:8572447 A/G cg18904891 chr8:8559673 CLDN23 0.62 5.7 0.46 8.41e-8 Obesity-related traits; TGCT cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg25036284 chr2:26402008 FAM59B -0.66 -5.34 -0.43 4.22e-7 Gut microbiome composition (summer); TGCT cis rs7474896 0.515 rs2749582 chr10:38275284 A/G cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs7635838 0.892 rs9310383 chr3:11491305 A/G cg00170343 chr3:11313890 ATG7 -0.66 -6.15 -0.48 1e-8 HDL cholesterol; TGCT cis rs12791968 1.000 rs11604565 chr11:45010336 A/G cg11846598 chr11:44996168 LOC221122 -0.32 -5.92 -0.47 2.92e-8 Inhibitory control; TGCT cis rs6429082 0.818 rs291381 chr1:235641924 A/G cg26050004 chr1:235667680 B3GALNT2 0.62 5.58 0.45 1.43e-7 Adiposity; TGCT cis rs6582630 0.519 rs9738104 chr12:38338459 A/C cg26384229 chr12:38710491 ALG10B 0.83 7.29 0.55 3.15e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs12477438 0.765 rs2278895 chr2:99613484 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg11279151 chr3:101281821 RG9MTD1 -0.45 -9.88 -0.66 2.52e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs3892630 0.817 rs12609866 chr19:33184412 C/T cg22980127 chr19:33182716 NUDT19 0.7 5.18 0.42 8.9e-7 Red blood cell traits; TGCT cis rs2836950 0.501 rs1474490 chr21:40716136 C/A cg06238570 chr21:40685208 BRWD1 -0.62 -6.23 -0.49 6.61e-9 Menarche (age at onset); TGCT cis rs838147 0.508 rs507711 chr19:49208564 C/T cg10667338 chr19:49617042 LIN7B -0.34 -4.56 -0.38 1.19e-5 Dietary macronutrient intake; TGCT cis rs8103278 1.000 rs11671524 chr19:46327166 G/A cg14061069 chr19:46274453 DMPK -0.44 -6.14 -0.48 1.04e-8 Coronary artery disease; TGCT cis rs763121 0.962 rs138711 chr22:39139913 C/T cg06022373 chr22:39101656 GTPBP1 0.84 5.41 0.44 3.18e-7 Menopause (age at onset); TGCT cis rs922182 0.557 rs7161953 chr15:64202887 C/A cg02919090 chr15:64263738 DAPK2 -0.38 -7.0 -0.53 1.4e-10 Blood protein levels; TGCT cis rs9926296 0.585 rs8058009 chr16:89856439 G/A cg27121462 chr16:89883253 FANCA 0.54 4.59 0.38 1.05e-5 Vitiligo; TGCT cis rs68170813 0.559 rs80341862 chr7:106934731 C/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT trans rs10802346 0.545 rs10924545 chr1:246364592 C/T cg13514129 chr1:39547527 MACF1 -0.85 -7.83 -0.58 1.89e-12 Fractional exhaled nitric oxide (childhood); TGCT cis rs10927875 0.691 rs2017583 chr1:16350028 A/G cg21385522 chr1:16154831 NA 0.62 6.38 0.5 3.17e-9 Dilated cardiomyopathy; TGCT cis rs12477438 0.798 rs6759354 chr2:99632195 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs1371867 0.839 rs1660313 chr8:101332712 G/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs12477438 0.798 rs1530996 chr2:99584079 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.99 -0.47 2.09e-8 Chronic sinus infection; TGCT cis rs453301 0.606 rs6981060 chr8:8908235 C/A cg06636001 chr8:8085503 FLJ10661 -0.71 -5.8 -0.46 5.19e-8 Joint mobility (Beighton score); TGCT cis rs11864453 0.647 rs8043606 chr16:72135319 T/C cg14768367 chr16:72042858 DHODH 0.52 5.27 0.43 5.78e-7 Fibrinogen levels; TGCT cis rs6430585 1.000 rs6732236 chr2:136501509 T/G cg07169764 chr2:136633963 MCM6 0.89 7.96 0.58 9.17e-13 Corneal structure; TGCT cis rs6121246 0.954 rs6060989 chr20:30429763 C/T cg18721089 chr20:30220636 NA -0.45 -4.98 -0.41 2.12e-6 Mean corpuscular hemoglobin; TGCT cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs752010 0.619 rs6703992 chr1:42115888 G/A cg06885757 chr1:42089581 HIVEP3 0.28 4.84 0.4 3.74e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg07507251 chr3:52567010 NT5DC2 -0.46 -6.34 -0.49 3.89e-9 Bipolar disorder; TGCT cis rs826838 0.709 rs4882355 chr12:38721462 A/T cg26384229 chr12:38710491 ALG10B 0.64 6.0 0.47 2.03e-8 Heart rate; TGCT cis rs7584330 0.868 rs6760842 chr2:238398165 C/T cg11271282 chr2:238384023 NA -0.58 -4.45 -0.37 1.89e-5 Prostate cancer; TGCT cis rs4919044 0.674 rs9419766 chr10:94800788 G/A cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs17681684 0.505 rs62064492 chr17:9803713 G/A cg15743799 chr17:9805578 RCVRN -0.28 -6.33 -0.49 4.01e-9 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs13256369 1.000 rs10103769 chr8:8573036 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.44 0.37 1.99e-5 Obesity-related traits; TGCT cis rs9302065 0.565 rs2992910 chr13:95962216 T/A cg24476569 chr13:95954382 ABCC4 -0.54 -8.26 -0.6 1.9e-13 Blood metabolite levels; TGCT cis rs7611238 0.560 rs6763335 chr3:195076218 A/C cg27323046 chr3:195102265 ACAP2 0.37 5.0 0.41 1.9e-6 Body mass index; TGCT cis rs17767294 0.708 rs75543204 chr6:28108816 C/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs6728642 0.572 rs7574488 chr2:97599618 T/C cg26665480 chr2:98280029 ACTR1B -0.91 -6.78 -0.52 4.32e-10 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs17133449 0.718 rs2167695 chr10:4753980 G/C cg04530666 chr10:3759553 NA -0.28 -4.68 -0.39 7.48e-6 Major depressive disorder; TGCT cis rs7552167 0.925 rs7546025 chr1:24510252 T/C cg01960748 chr1:24522592 NA -0.49 -5.51 -0.44 2.02e-7 Psoriasis vulgaris; TGCT cis rs7568458 0.870 rs1010 chr2:85808982 C/T cg17127132 chr2:85788382 GGCX -0.68 -6.2 -0.49 7.7e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs12188164 1.000 rs34453673 chr5:434722 G/C cg21144161 chr5:423903 AHRR 0.24 4.59 0.38 1.06e-5 Cystic fibrosis severity; TGCT cis rs13082711 0.554 rs10514679 chr3:27412591 A/G cg02860705 chr3:27208620 NA 0.41 5.87 0.47 3.64e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs514406 0.861 rs4926577 chr1:53226788 C/A cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.41 2.55e-6 Monocyte count; TGCT cis rs1629083 0.935 rs1056562 chr11:118125625 T/C cg16594165 chr11:118135105 MPZL2 -0.33 -4.62 -0.38 9.6e-6 Lung cancer; TGCT cis rs1218582 0.774 rs4845683 chr1:154877407 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.65 -6.51 -0.5 1.68e-9 Prostate cancer; TGCT cis rs77972916 0.505 rs6753197 chr2:43527962 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -5.68 -0.45 9.24e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs986417 0.606 rs7156375 chr14:61110627 G/A cg18240143 chr14:60952599 C14orf39 0.88 4.57 0.38 1.15e-5 Gut microbiota (bacterial taxa); TGCT cis rs7914558 1.000 rs7077097 chr10:104945463 G/A cg15744005 chr10:104629667 AS3MT -0.39 -4.73 -0.39 5.91e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs11098499 0.954 rs6847248 chr4:120225955 A/G cg09307838 chr4:120376055 NA 0.63 5.88 0.47 3.6e-8 Corneal astigmatism; TGCT cis rs78545713 1.000 rs78545713 chr6:26248840 A/G cg12260798 chr6:26240519 HIST1H4F -0.59 -4.89 -0.4 3.09e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs1362404 0.582 rs12149211 chr16:51961345 C/A cg03955530 chr16:52681474 NA 0.3 4.72 0.39 6.36e-6 Gut microbiota (bacterial taxa); TGCT cis rs76419734 0.850 rs11725523 chr4:106517866 G/A cg24545054 chr4:106630052 GSTCD;INTS12 1.08 4.44 0.37 1.93e-5 Post bronchodilator FEV1; TGCT cis rs7914558 0.966 rs2297786 chr10:104679978 C/T cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6450176 1.000 rs58369491 chr5:53297295 T/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.12 -0.42 1.15e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT trans rs2688608 0.592 rs11000757 chr10:75486815 T/C cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs6424115 0.830 rs2229584 chr1:24200969 T/C cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs2832191 0.791 rs2832187 chr21:30485543 T/C cg08807101 chr21:30365312 RNF160 -0.64 -6.01 -0.48 1.9e-8 Dental caries; TGCT cis rs924607 1.000 rs11746907 chr5:598224 G/A cg18765565 chr5:669397 TPPP -0.59 -6.34 -0.49 3.83e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs950169 0.922 rs11633075 chr15:85113972 C/A cg12863693 chr15:85201151 NMB 0.39 4.44 0.37 1.99e-5 Schizophrenia; TGCT cis rs77633900 0.614 rs280028 chr15:77031466 A/G cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg21951975 chr1:209979733 IRF6 0.66 5.69 0.45 8.77e-8 Cleft lip with or without cleft palate; TGCT cis rs36051895 0.632 rs62541916 chr9:5151904 C/A cg02405213 chr9:5042618 JAK2 -0.75 -9.81 -0.66 3.66e-17 Pediatric autoimmune diseases; TGCT cis rs367943 1.000 rs2248930 chr5:112811119 G/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs6490294 0.752 rs608814 chr12:112126615 C/A cg10833066 chr12:111807467 FAM109A 0.35 5.08 0.42 1.34e-6 Mean platelet volume; TGCT cis rs9733 0.596 rs11803569 chr1:150664077 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs72781680 1.000 rs72796337 chr2:24142957 G/A cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs6546847 0.531 rs2567603 chr2:73986125 C/G cg07208825 chr2:73871855 ALMS1P 0.29 5.27 0.43 5.73e-7 Urinary metabolites (H-NMR features); TGCT cis rs10992471 0.603 rs10820968 chr9:95106443 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.49 -0.44 2.14e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs55883249 1.000 rs60319753 chr2:9767944 A/G cg23886495 chr2:9695866 ADAM17 0.75 4.7 0.39 6.76e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs11249608 0.636 rs6888539 chr5:178449010 T/A cg21905437 chr5:178450457 ZNF879 0.45 4.48 0.37 1.67e-5 Pubertal anthropometrics; TGCT cis rs5769707 0.681 rs135879 chr22:50018651 C/T cg06623630 chr22:50017776 C22orf34 -0.27 -4.58 -0.38 1.11e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9372498 0.536 rs10484286 chr6:118956447 T/C cg07617317 chr6:118971624 C6orf204 0.47 4.95 0.41 2.33e-6 Diastolic blood pressure; TGCT cis rs7727544 0.582 rs6896703 chr5:131521295 C/G cg14196790 chr5:131705035 SLC22A5 -0.35 -4.56 -0.38 1.23e-5 Blood metabolite levels; TGCT cis rs344364 0.511 rs2982446 chr16:1947153 C/T cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs6121246 0.697 rs6088864 chr20:30228157 G/A cg18721089 chr20:30220636 NA -0.53 -5.43 -0.44 2.86e-7 Mean corpuscular hemoglobin; TGCT cis rs6540559 0.611 rs76766079 chr1:209997731 C/T cg21951975 chr1:209979733 IRF6 0.65 4.84 0.4 3.78e-6 Cleft lip with or without cleft palate; TGCT cis rs7572733 0.515 rs35730302 chr2:198818626 A/T cg00792783 chr2:198669748 PLCL1 -0.58 -5.31 -0.43 4.9e-7 Dermatomyositis; TGCT cis rs7914558 1.000 rs67908413 chr10:104764989 T/C cg15744005 chr10:104629667 AS3MT -0.39 -4.77 -0.39 5.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7267979 1.000 rs6076339 chr20:25348712 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs71597109 0.681 rs4699260 chr4:102725298 C/T cg14855874 chr4:102712397 BANK1 0.41 4.86 0.4 3.43e-6 Chronic lymphocytic leukemia; TGCT trans rs877282 0.945 rs11253388 chr10:787852 A/G cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs2404602 0.583 rs2176623 chr15:76568579 C/T cg22467129 chr15:76604101 ETFA -0.61 -7.62 -0.56 5.66e-12 Blood metabolite levels; TGCT cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg03806693 chr22:41940476 POLR3H -1.11 -11.93 -0.73 2.47e-22 Vitiligo; TGCT cis rs2836950 0.501 rs13047518 chr21:40707307 G/A cg11890956 chr21:40555474 PSMG1 -0.64 -5.9 -0.47 3.27e-8 Menarche (age at onset); TGCT cis rs7635838 0.523 rs9873503 chr3:11396100 T/C cg00170343 chr3:11313890 ATG7 0.64 6.15 0.48 9.73e-9 HDL cholesterol; TGCT cis rs539096 0.500 rs803678 chr1:44350898 G/T cg12908607 chr1:44402522 ARTN -0.7 -8.79 -0.62 1.01e-14 Intelligence (multi-trait analysis); TGCT cis rs7659604 0.676 rs4077102 chr4:122699830 A/G cg19748678 chr4:122722346 EXOSC9 0.87 9.22 0.64 9.65e-16 Type 2 diabetes; TGCT cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs35160687 0.901 rs67903513 chr2:86512099 A/C cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.51e-7 Night sleep phenotypes; TGCT cis rs10779751 1.000 rs11121704 chr1:11293959 A/G cg08854313 chr1:11322531 MTOR -1.04 -8.94 -0.63 4.5e-15 Body mass index; TGCT cis rs1577917 0.958 rs12660846 chr6:86573809 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.47 -0.44 2.33e-7 Response to antipsychotic treatment; TGCT cis rs60154123 0.505 rs76426571 chr1:210041634 C/T cg22029157 chr1:209979665 IRF6 0.79 5.78 0.46 5.6e-8 Coronary artery disease; TGCT cis rs2281636 1.000 rs2804417 chr10:101516215 G/A cg17885402 chr10:101492224 COX15;CUTC -0.57 -4.49 -0.37 1.58e-5 Obesity-related traits; TGCT cis rs2299587 0.573 rs6986123 chr8:17888073 G/A cg01800426 chr8:17659068 MTUS1 -0.6 -5.1 -0.42 1.25e-6 Economic and political preferences; TGCT cis rs651907 0.557 rs34457525 chr3:101435225 C/T cg12386194 chr3:101231763 SENP7 0.51 4.9 0.4 2.89e-6 Colorectal cancer; TGCT cis rs4654899 0.865 rs960564 chr1:21416435 G/T cg01072550 chr1:21505969 NA -0.46 -6.9 -0.53 2.33e-10 Superior frontal gyrus grey matter volume; TGCT trans rs9295123 0.965 rs4709402 chr6:160574037 C/T cg22927510 chr22:50968328 TYMP -0.51 -6.96 -0.53 1.79e-10 Blood protein levels; TGCT cis rs617219 0.710 rs2607142 chr5:78557948 T/C cg05890484 chr5:78407552 BHMT 0.34 4.63 0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7524258 0.903 rs763197 chr1:7289959 A/G cg07173049 chr1:7289937 CAMTA1 0.32 5.31 0.43 4.88e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs497273 0.552 rs1179939 chr12:121326876 G/C cg02419362 chr12:121203948 SPPL3 -0.19 -4.51 -0.38 1.48e-5 Systemic lupus erythematosus; TGCT cis rs11690462 0.794 rs2384364 chr2:26541427 C/G cg04726446 chr2:26624865 C2orf39 0.42 4.53 0.38 1.39e-5 Coronary artery disease; TGCT cis rs9916302 0.800 rs11869259 chr17:37518141 C/A cg07936489 chr17:37558343 FBXL20 0.65 5.09 0.42 1.3e-6 Glomerular filtration rate (creatinine); TGCT cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.45 6.41 0.5 2.77e-9 Alzheimer's disease; TGCT cis rs6500602 0.702 rs2058812 chr16:4524443 C/G cg08645402 chr16:4508243 NA 0.16 4.59 0.38 1.09e-5 Schizophrenia; TGCT cis rs4363385 0.525 rs11205138 chr1:152890568 G/A cg07796016 chr1:152779584 LCE1C -0.49 -5.65 -0.45 1.02e-7 Inflammatory skin disease; TGCT cis rs7714584 1.000 rs10463310 chr5:150260905 G/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT trans rs621559 0.535 rs620455 chr1:43671144 G/A cg19324027 chr2:74699582 MRPL53 0.87 6.75 0.52 5.12e-10 Telomere length; TGCT cis rs589448 0.934 rs554591 chr12:69753847 T/C cg11871910 chr12:69753446 YEATS4 0.87 10.07 0.67 8.72e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs6088580 0.634 rs6059835 chr20:33020141 A/G cg24642439 chr20:33292090 TP53INP2 0.49 4.51 0.38 1.5e-5 Glomerular filtration rate (creatinine); TGCT cis rs7586879 0.638 rs13035244 chr2:25134009 T/C cg15423357 chr2:25149977 NA 0.52 5.04 0.41 1.63e-6 Body mass index; TGCT cis rs514406 0.548 rs6670871 chr1:53212082 A/C cg24675658 chr1:53192096 ZYG11B 0.83 10.11 0.67 6.99e-18 Monocyte count; TGCT cis rs9549367 0.713 rs3024776 chr13:113827075 A/G cg18105134 chr13:113819100 PROZ 0.48 8.44 0.6 7.06e-14 Platelet distribution width; TGCT cis rs11030122 0.673 rs4910597 chr11:4094923 G/A cg18678763 chr11:4115507 RRM1 -0.47 -5.62 -0.45 1.21e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs9611565 0.592 rs5758427 chr22:42099688 A/G cg17554472 chr22:41940697 POLR3H 0.48 5.17 0.42 9e-7 Vitiligo; TGCT cis rs7017914 0.934 rs78923624 chr8:71677839 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs7432375 0.901 rs11919030 chr3:136348599 G/A cg12473912 chr3:136751656 NA 0.34 4.82 0.4 4.1e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs1878931 1.000 rs1878931 chr16:3450907 G/C cg03543448 chr16:4384967 GLIS2 0.19 4.76 0.39 5.26e-6 Body mass index (adult); TGCT cis rs9902453 0.933 rs9303628 chr17:28527228 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.31e-10 Coffee consumption (cups per day); TGCT cis rs265548 0.646 rs36689 chr19:17910639 A/G cg21960279 chr19:17905606 B3GNT3 0.49 5.73 0.46 7.21e-8 Tumor biomarkers; TGCT cis rs77633900 0.614 rs280030 chr15:77026853 T/C cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs422249 0.512 rs174568 chr11:61593816 C/T cg19610905 chr11:61596333 FADS2 -1.07 -12.03 -0.73 1.43e-22 Trans fatty acid levels; TGCT cis rs6725041 0.819 rs939225 chr2:213089002 T/C cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs2204008 0.728 rs11495375 chr12:38282631 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs796364 0.616 rs2689765 chr2:200696352 T/C cg17644776 chr2:200775616 C2orf69 0.35 4.99 0.41 1.97e-6 Schizophrenia; TGCT cis rs1577917 0.876 rs1582126 chr6:86697205 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.33 -0.43 4.54e-7 Response to antipsychotic treatment; TGCT cis rs902774 0.530 rs12819597 chr12:53353956 T/C cg16329197 chr12:53359506 NA -0.56 -4.71 -0.39 6.44e-6 Prostate cancer; TGCT cis rs6540559 0.673 rs58637469 chr1:209971480 T/A cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs317689 0.918 rs581911 chr12:69738293 C/T cg14784868 chr12:69753453 YEATS4 0.53 4.45 0.37 1.9e-5 Response to diuretic therapy; TGCT cis rs2228479 0.717 rs11644967 chr16:89806614 T/A cg04287289 chr16:89883240 FANCA 0.74 4.47 0.37 1.75e-5 Skin colour saturation; TGCT cis rs826838 1.000 rs34254519 chr12:39041235 G/A cg26384229 chr12:38710491 ALG10B 1.01 9.61 0.65 1.09e-16 Heart rate; TGCT cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg26531700 chr6:26746687 NA 0.5 4.64 0.38 8.54e-6 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.735 rs858512 chr7:99824453 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs896854 0.967 rs896853 chr8:95960855 G/C cg13393036 chr8:95962371 TP53INP1 -0.65 -9.03 -0.63 2.75e-15 Type 2 diabetes; TGCT cis rs1887596 0.705 rs4771004 chr13:27214082 A/G cg01312412 chr13:27282625 NA 0.31 5.47 0.44 2.43e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs9467711 0.516 rs1165184 chr6:25836257 C/G cg03517284 chr6:25882590 NA -0.73 -5.02 -0.41 1.77e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs892961 0.899 rs3650 chr17:75415835 T/C cg05865280 chr17:75406074 SEPT9 0.29 6.71 0.52 6.23e-10 Airflow obstruction; TGCT cis rs17387100 0.551 rs16892805 chr4:16019505 C/G cg13480465 chr4:16795757 LDB2 0.42 5.33 0.43 4.56e-7 Suicide attempts in depression or bipolar disorder; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg04352962 chr1:209979756 IRF6 0.76 8.41 0.6 8.36e-14 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs6582630 0.519 rs8189549 chr12:38245752 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.42 0.55 1.6e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1483890 0.962 rs1483891 chr3:69410416 G/C cg22125112 chr3:69402811 FRMD4B 0.27 4.52 0.38 1.45e-5 Resting heart rate; TGCT cis rs13217239 0.646 rs10456351 chr6:26986792 C/T cg26531700 chr6:26746687 NA 0.68 6.79 0.52 4.1e-10 Schizophrenia; TGCT cis rs4494114 1.000 rs4494114 chr1:39339682 C/T cg25970120 chr1:39325951 RRAGC 0.6 6.28 0.49 5.34e-9 Blood protein levels; TGCT cis rs1372520 0.684 rs2583968 chr4:90745395 C/G cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.11e-7 Neuroticism; TGCT cis rs2370759 0.898 rs113412621 chr10:32579306 C/T cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs10255878 0.568 rs17168494 chr7:97041088 T/C cg01534613 chr7:96337050 SHFM1 0.29 4.47 0.37 1.73e-5 Adverse response to radiation therapy; TGCT cis rs951366 0.903 rs823116 chr1:205720483 G/A cg14893161 chr1:205819251 PM20D1 0.37 4.54 0.38 1.31e-5 Menarche (age at onset); TGCT cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -5.0 -0.41 1.92e-6 Bipolar disorder; TGCT cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg03303774 chr4:1407052 NA 0.31 4.87 0.4 3.31e-6 Obesity-related traits; TGCT cis rs7617773 0.817 rs34728236 chr3:48259108 A/G cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs79149102 0.579 rs7172715 chr15:75287375 C/G cg09165964 chr15:75287851 SCAMP5 -1.06 -5.63 -0.45 1.17e-7 Lung cancer; TGCT cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg23758822 chr17:41437982 NA 0.72 6.91 0.53 2.23e-10 Menopause (age at onset); TGCT cis rs2201728 0.905 rs7662955 chr4:100217128 G/A cg07219303 chr4:100140905 ADH6 -0.36 -5.31 -0.43 4.8e-7 Cardiac Troponin-T levels; TGCT cis rs9311474 0.713 rs352165 chr3:52242902 A/G cg10802521 chr3:52805072 NEK4 -0.61 -6.58 -0.51 1.19e-9 Electroencephalogram traits; TGCT cis rs2652822 0.507 rs7176597 chr15:63494482 G/A cg12855773 chr15:63363890 TPM1 -0.17 -4.84 -0.4 3.79e-6 Metabolic traits; TGCT cis rs877282 0.945 rs11253390 chr10:788678 A/G cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs6815814 0.950 rs5743795 chr4:38832495 C/T cg02016764 chr4:38805732 TLR1 -0.32 -4.91 -0.4 2.75e-6 Breast cancer; TGCT cis rs524281 0.861 rs11227426 chr11:65971951 T/C cg00563793 chr11:65837595 PACS1 0.53 4.56 0.38 1.2e-5 Electroencephalogram traits; TGCT cis rs6540559 0.611 rs76766079 chr1:209997731 C/T cg23283495 chr1:209979779 IRF6 0.61 4.53 0.38 1.36e-5 Cleft lip with or without cleft palate; TGCT cis rs9549367 0.713 rs3024746 chr13:113821777 G/A cg09473364 chr13:112927190 NA -0.3 -4.44 -0.37 1.95e-5 Platelet distribution width; TGCT cis rs7829975 0.606 rs6601274 chr8:8799059 T/G cg08975724 chr8:8085496 FLJ10661 -0.53 -4.51 -0.38 1.47e-5 Mood instability; TGCT cis rs9646954 0.542 rs11674830 chr2:101024735 A/G cg14675211 chr2:100938903 LONRF2 0.5 4.66 0.39 7.99e-6 Intelligence (multi-trait analysis); TGCT cis rs11122272 0.735 rs2066140 chr1:231504311 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -5.97 -0.47 2.33e-8 Hemoglobin concentration; TGCT cis rs2404602 0.647 rs11072625 chr15:77084984 A/G cg23625390 chr15:77176239 SCAPER 0.36 4.52 0.38 1.4e-5 Blood metabolite levels; TGCT cis rs727479 0.543 rs4324076 chr15:51510868 A/C cg19946085 chr15:51559439 CYP19A1 -0.3 -4.49 -0.37 1.62e-5 Estradiol levels; TGCT cis rs854765 0.624 rs4925119 chr17:17742904 A/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.53 -0.38 1.39e-5 Total body bone mineral density; TGCT cis rs587847 0.767 rs28668771 chr15:37688017 A/G cg12309653 chr15:37170454 LOC145845 0.31 4.48 0.37 1.7e-5 Intraocular pressure; TGCT cis rs875971 0.638 rs6460305 chr7:66060408 G/A cg18876405 chr7:65276391 NA -0.37 -5.58 -0.45 1.47e-7 Aortic root size; TGCT cis rs12210905 0.688 rs72841399 chr6:27489832 T/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs1981331 1.000 rs118078026 chr21:48012129 T/C cg23283320 chr21:48055893 PRMT2 1.29 6.09 0.48 1.31e-8 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs4808199 0.843 rs10402308 chr19:19657500 G/A cg03709012 chr19:19516395 GATAD2A 0.93 7.21 0.54 4.93e-11 Nonalcoholic fatty liver disease; TGCT cis rs6500602 0.563 rs917304 chr16:4440426 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 5.1 0.42 1.23e-6 Schizophrenia; TGCT cis rs9430161 0.611 rs34032547 chr1:11034374 C/G cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.64 7.0 0.53 1.43e-10 Blood metabolite levels; TGCT trans rs7618501 1.000 rs2247036 chr3:49882349 C/T cg21659725 chr3:3221576 CRBN 0.97 14.99 0.8 1.29e-29 Intelligence (multi-trait analysis); TGCT cis rs1801251 0.778 rs2675967 chr2:233736133 C/G cg25237894 chr2:233734115 C2orf82 -0.3 -5.85 -0.46 4.16e-8 Coronary artery disease; TGCT cis rs7681440 0.904 rs28507349 chr4:90767063 G/A cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs4927850 1.000 rs4927850 chr3:195751630 C/T cg12923728 chr3:195709715 SDHAP1 0.36 7.66 0.57 4.64e-12 Pancreatic cancer; TGCT cis rs9393777 0.513 rs13215020 chr6:26656073 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs939658 0.805 rs35484723 chr15:79441032 A/G cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs12188164 0.610 rs57433159 chr5:418725 C/T cg26850624 chr5:429559 AHRR -0.19 -4.45 -0.37 1.89e-5 Cystic fibrosis severity; TGCT cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs10927875 0.793 rs1763619 chr1:16326935 A/G cg22431228 chr1:16359049 CLCNKA -0.25 -4.8 -0.4 4.39e-6 Dilated cardiomyopathy; TGCT cis rs4803468 0.967 rs13345590 chr19:41886455 T/G cg09537434 chr19:41945824 ATP5SL -0.88 -9.98 -0.67 1.4e-17 Height; TGCT cis rs9611519 0.579 rs8136274 chr22:41415311 T/C cg03806693 chr22:41940476 POLR3H -0.64 -6.09 -0.48 1.29e-8 Neuroticism; TGCT cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10114408 0.959 rs10821256 chr9:96657044 C/T cg13679303 chr9:96623674 NA -0.36 -4.65 -0.39 8.3e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs3796352 0.571 rs71301816 chr3:53142071 G/A cg07884673 chr3:53033167 SFMBT1 0.57 6.13 0.48 1.09e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7267979 0.966 rs6050532 chr20:25308793 A/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8031584 0.678 rs8028173 chr15:31155749 A/G cg08109568 chr15:31115862 NA -0.38 -5.03 -0.41 1.67e-6 Huntington's disease progression; TGCT cis rs1475911 0.708 rs8129075 chr21:43523430 G/T cg14562523 chr21:43528734 C21orf128;UMODL1 -0.28 -5.69 -0.45 8.8e-8 IgG glycosylation; TGCT cis rs6426558 0.537 rs2102634 chr1:227324308 T/C cg10327440 chr1:227177885 CDC42BPA -0.58 -6.91 -0.53 2.21e-10 Neutrophil percentage of white cells; TGCT cis rs2115630 0.967 rs12595786 chr15:85336670 T/C cg17173187 chr15:85201210 NMB -0.4 -4.86 -0.4 3.51e-6 P wave terminal force; TGCT cis rs8072100 0.537 rs9912450 chr17:45402208 C/T cg08085267 chr17:45401833 C17orf57 -0.59 -6.48 -0.5 1.99e-9 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs12615966 1.000 rs12618379 chr2:105386854 C/T cg16465502 chr2:105461796 NA 0.78 4.98 0.41 2.11e-6 Pancreatic cancer; TGCT cis rs79387448 0.638 rs11465698 chr2:103054577 T/C cg09003973 chr2:102972529 NA 1.27 9.82 0.66 3.37e-17 Gut microbiota (bacterial taxa); TGCT cis rs798554 0.704 rs798531 chr7:2770067 G/C cg25467336 chr7:2757616 NA -0.24 -4.61 -0.38 9.99e-6 Height; TGCT cis rs6752107 1.000 rs12994971 chr2:234178453 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.8 0.4 4.54e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs929354 0.772 rs2301916 chr7:156974127 G/T cg05182265 chr7:156933206 UBE3C -0.38 -8.59 -0.61 3.18e-14 Body mass index; TGCT cis rs7428 0.502 rs3184781 chr2:85549527 T/C cg03728395 chr2:85555865 TGOLN2 -0.29 -5.09 -0.42 1.32e-6 Ear protrusion; TGCT cis rs9372498 0.536 rs25422 chr6:118807847 A/G cg21191810 chr6:118973309 C6orf204 0.39 4.95 0.41 2.32e-6 Diastolic blood pressure; TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs10540 1.000 rs35255804 chr11:492617 G/A cg03934478 chr11:495069 RNH1 0.35 5.81 0.46 4.96e-8 Body mass index; TGCT cis rs6665290 0.901 rs11580229 chr1:227210820 G/A cg10327440 chr1:227177885 CDC42BPA -0.91 -16.3 -0.83 1.24e-32 Myeloid white cell count; TGCT cis rs1577917 0.710 rs9342041 chr6:86280875 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 4.61 0.38 9.81e-6 Response to antipsychotic treatment; TGCT trans rs1814175 0.817 rs7924619 chr11:49620632 G/A cg03929089 chr4:120376271 NA -0.74 -8.94 -0.63 4.47e-15 Height; TGCT cis rs6598955 0.671 rs13374173 chr1:26602256 T/G cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs1008375 1.000 rs12648232 chr4:17612537 C/T cg18681998 chr4:17616180 MED28 -0.98 -11.03 -0.7 3.92e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9467773 1.000 rs9467778 chr6:26534743 T/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs9534288 0.699 rs2296642 chr13:46656669 A/G cg15192986 chr13:46630673 CPB2 -0.53 -6.5 -0.5 1.8e-9 Blood protein levels; TGCT cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg12034118 chr1:209979487 IRF6 0.68 5.13 0.42 1.07e-6 Cleft lip with or without cleft palate; TGCT cis rs9902453 0.757 rs12453308 chr17:28441604 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.5 0.5 1.77e-9 Coffee consumption (cups per day); TGCT cis rs9929218 0.954 rs17715762 chr16:68828250 T/G cg03880890 chr16:69439245 NA -0.22 -4.48 -0.37 1.68e-5 Colorectal cancer; TGCT cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs4919669 0.668 rs74558061 chr10:104384337 A/G cg05855489 chr10:104503620 C10orf26 0.7 4.44 0.37 1.94e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs1215050 0.791 rs1530904 chr4:98805436 A/G cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28735056 0.967 rs4799092 chr18:77608203 C/G cg20368463 chr18:77673604 PQLC1 -0.44 -5.46 -0.44 2.44e-7 Schizophrenia; TGCT cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.844 rs6132824 chr20:25238173 T/C cg16686733 chr20:25566563 NINL 0.52 4.9 0.4 2.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6978712 1.000 rs17714284 chr7:127147205 G/A cg01017541 chr7:127776461 NA 0.79 4.76 0.39 5.3e-6 Medication adherence in chronic diseases; TGCT cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.25 4.75 0.39 5.51e-6 Total body bone mineral density; TGCT cis rs12950390 0.893 rs4239166 chr17:45847329 A/G cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.6e-6 IgG glycosylation; TGCT cis rs10465746 0.725 rs980417 chr1:84365331 C/A cg10977910 chr1:84465055 TTLL7 0.68 6.7 0.52 6.46e-10 Obesity-related traits; TGCT cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs7267979 0.740 rs2259961 chr20:25282626 T/G cg14121845 chr20:25566513 NINL 0.45 4.6 0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.686 rs857877 chr6:145976230 A/C cg05347473 chr6:146136440 FBXO30 -0.49 -4.59 -0.38 1.06e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs11098499 0.754 rs17595608 chr4:120250506 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs6860806 0.507 rs2631369 chr5:131705266 G/C cg24060327 chr5:131705240 SLC22A5 0.78 8.62 0.61 2.62e-14 Breast cancer; TGCT cis rs7296418 0.754 rs1619283 chr12:123717362 A/G cg05973401 chr12:123451056 ABCB9 0.54 4.51 0.38 1.48e-5 Platelet count; TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg14159672 chr1:205819179 PM20D1 0.6 7.44 0.56 1.45e-11 Menarche (age at onset); TGCT cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg08219700 chr8:58056026 NA 0.3 4.58 0.38 1.13e-5 Developmental language disorder (linguistic errors); TGCT cis rs4074961 0.586 rs10908360 chr1:38058693 T/C cg11397548 chr1:38022522 DNALI1 0.42 4.52 0.38 1.44e-5 Axial length; TGCT cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg04352962 chr1:209979756 IRF6 0.64 4.89 0.4 3.12e-6 Cleft lip with or without cleft palate; TGCT cis rs7267979 0.934 rs6037085 chr20:25305202 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2735413 0.564 rs2344491 chr16:78096154 A/G cg09132178 chr16:78079569 NA 0.33 4.44 0.37 1.98e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs10791097 0.739 rs12279359 chr11:130730544 G/A cg12179176 chr11:130786555 SNX19 0.73 8.6 0.61 2.98e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4372836 0.518 rs1128416 chr2:29001691 A/G cg09522027 chr2:28974177 PPP1CB -0.77 -7.59 -0.56 6.62e-12 Body mass index; TGCT cis rs138249 1.000 rs138252 chr22:50570873 G/T cg24864161 chr22:50528282 MOV10L1 0.46 4.71 0.39 6.51e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg06873352 chr17:61820015 STRADA 0.56 6.19 0.49 8.27e-9 Prudent dietary pattern; TGCT cis rs3796352 1.000 rs11717619 chr3:53003179 A/C cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT trans rs561341 0.941 rs17780086 chr17:30343282 G/A cg20587970 chr11:113659929 NA -1.09 -13.5 -0.77 4.23e-26 Hip circumference adjusted for BMI; TGCT cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.09 0.42 1.32e-6 Colorectal cancer; TGCT cis rs2456568 0.835 rs7936182 chr11:93665532 T/A cg16099599 chr11:93583650 C11orf90 -0.4 -4.72 -0.39 6.21e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7587476 0.601 rs1129804 chr2:215674323 C/G cg04004882 chr2:215674386 BARD1 -0.65 -5.13 -0.42 1.09e-6 Neuroblastoma; TGCT cis rs3812831 0.662 rs407531 chr13:114929218 G/A cg08824895 chr13:115047677 UPF3A 0.51 4.84 0.4 3.82e-6 Schizophrenia; TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs9972944 0.702 rs6416946 chr17:63763967 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.29 -0.43 5.45e-7 Total body bone mineral density; TGCT cis rs10193935 1.000 rs13391906 chr2:42538617 C/G cg27598129 chr2:42591480 NA -0.41 -5.65 -0.45 1.04e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11690935 0.959 rs2674484 chr2:172574612 G/A cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs1371867 0.875 rs1660311 chr8:101330579 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg20607798 chr8:58055168 NA 0.45 4.66 0.39 7.88e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs6546744 chr2:26302161 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs57221529 0.600 rs11750269 chr5:666270 G/A cg20362242 chr5:692897 TPPP 0.52 4.76 0.39 5.4e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7611238 0.560 rs9288746 chr3:195158031 T/C cg27323046 chr3:195102265 ACAP2 0.33 4.44 0.37 1.96e-5 Body mass index; TGCT cis rs7119 0.671 rs10152850 chr15:77904426 G/A cg27398640 chr15:77910606 LINGO1 0.32 6.74 0.52 5.39e-10 Type 2 diabetes; TGCT cis rs7937682 0.921 rs688354 chr11:111438762 A/G cg09085632 chr11:111637200 PPP2R1B -0.85 -7.67 -0.57 4.42e-12 Primary sclerosing cholangitis; TGCT cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg06481639 chr22:41940642 POLR3H 0.74 6.58 0.51 1.2e-9 Vitiligo; TGCT cis rs11190604 1.000 rs2489050 chr10:102350898 T/A cg23241863 chr10:102295624 HIF1AN 0.67 4.87 0.4 3.36e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28408315 0.914 rs34577742 chr15:79215568 C/T cg15822222 chr15:79164806 MORF4L1 0.49 5.18 0.42 8.55e-7 Lung cancer;Lung cancer in ever smokers;Lung adenocarcinoma; TGCT cis rs9486719 1.000 rs12197411 chr6:97039621 G/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs9303280 0.901 rs869402 chr17:38068043 C/T cg18711369 chr17:38081186 ORMDL3 0.23 4.85 0.4 3.6e-6 Self-reported allergy; TGCT cis rs7666738 0.830 rs11938686 chr4:98964470 A/G cg05340658 chr4:99064831 C4orf37 0.53 6.04 0.48 1.64e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7017914 0.967 rs7014012 chr8:71672743 G/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs6495122 0.630 rs12912343 chr15:75251041 C/G cg10253484 chr15:75165896 SCAMP2 -0.6 -5.33 -0.43 4.52e-7 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs910316 0.967 rs8007539 chr14:75664953 T/C cg11812906 chr14:75593930 NEK9 -0.71 -6.8 -0.52 3.94e-10 Height; TGCT cis rs903263 0.965 rs2037455 chr1:84645555 A/G cg09664975 chr1:84543551 PRKACB 0.47 4.48 0.37 1.65e-5 Breast cancer (male); TGCT cis rs12497850 0.931 rs7616815 chr3:48779715 C/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.74 0.46 6.86e-8 Parkinson's disease; TGCT cis rs6831352 0.877 rs28987101 chr4:100049253 T/G cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs7312933 0.618 rs6582390 chr12:42634586 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 5.05 0.41 1.54e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9868809 0.772 rs28452701 chr3:48708575 C/T cg00383909 chr3:49044727 WDR6 1.06 6.18 0.49 8.32e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs12579753 0.917 rs71466033 chr12:82242187 C/T cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs74233809 1.000 rs10509759 chr10:104689665 A/T cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs7829975 0.871 rs777709 chr8:8583872 T/C cg15556689 chr8:8085844 FLJ10661 -0.66 -5.77 -0.46 6.03e-8 Mood instability; TGCT cis rs7605378 0.528 rs281767 chr2:200823281 C/A cg23649088 chr2:200775458 C2orf69 0.47 9.83 0.66 3.23e-17 Osteoporosis; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg23131131 chr22:24373011 LOC391322 -0.81 -8.72 -0.62 1.53e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9372253 1.000 rs9384740 chr6:110716207 G/A cg00083206 chr6:110721305 DDO -0.43 -6.46 -0.5 2.2e-9 Platelet distribution width; TGCT trans rs1496653 0.602 rs13063451 chr3:23469372 T/C cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs425277 1.000 rs74877653 chr1:2065949 C/T cg03732007 chr1:2071316 PRKCZ 0.25 5.01 0.41 1.81e-6 Height; TGCT cis rs11080466 1.000 rs11663246 chr18:10900614 C/T cg02393756 chr18:9912783 VAPA -0.25 -4.47 -0.37 1.72e-5 Non-small cell lung cancer; TGCT cis rs12188164 0.965 rs72717415 chr5:430059 G/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.76 -0.39 5.27e-6 Cystic fibrosis severity; TGCT cis rs782590 0.620 rs4322879 chr2:55797033 G/T cg03859395 chr2:55845619 SMEK2 -0.71 -6.85 -0.52 3.13e-10 Metabolic syndrome; TGCT cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg03264133 chr6:25882463 NA -0.58 -5.22 -0.42 7.29e-7 Intelligence (multi-trait analysis); TGCT cis rs2242194 0.816 rs6671688 chr1:154994265 T/C cg09359103 chr1:154839909 KCNN3 -0.45 -6.33 -0.49 4.13e-9 Schizophrenia; TGCT cis rs1005277 0.505 rs200937 chr10:38135772 T/C cg13531842 chr10:38383804 ZNF37A -0.39 -4.58 -0.38 1.1e-5 Extrinsic epigenetic age acceleration; TGCT cis rs7552404 0.920 rs2788654 chr1:76219569 C/T cg10523679 chr1:76189770 ACADM 0.82 8.79 0.62 1.05e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 0.636 rs115738451 chr8:58055133 A/T cg08219700 chr8:58056026 NA 0.38 4.61 0.38 1e-5 Developmental language disorder (linguistic errors); TGCT cis rs6484504 0.576 rs58702363 chr11:31246397 C/A cg14844989 chr11:31128820 NA -0.23 -4.51 -0.38 1.47e-5 Red blood cell count; TGCT cis rs9372498 0.536 rs9489394 chr6:118758234 T/C cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs1801251 0.685 rs1515961 chr2:233623763 C/A cg08000102 chr2:233561755 GIGYF2 0.61 6.89 0.53 2.54e-10 Coronary artery disease; TGCT cis rs71435601 0.628 rs1712250 chr2:21386058 C/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs10782582 0.609 rs78556436 chr1:76352875 G/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs7220401 0.512 rs71371126 chr17:28002642 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.69 -6.14 -0.48 1.01e-8 Coronary artery disease; TGCT cis rs1401999 0.650 rs3749445 chr3:183638506 C/T cg01324343 chr3:183735012 ABCC5 0.69 8.13 0.59 3.77e-13 Anterior chamber depth; TGCT cis rs2832191 0.671 rs73346699 chr21:30515529 C/T cg24692254 chr21:30365293 RNF160 -0.62 -5.46 -0.44 2.44e-7 Dental caries; TGCT cis rs10804591 0.848 rs2811448 chr3:129314259 T/G cg07730360 chr3:128845626 NA 0.21 4.64 0.38 8.88e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8103278 1.000 rs35302007 chr19:46219145 G/C cg14061069 chr19:46274453 DMPK -0.45 -6.49 -0.5 1.86e-9 Coronary artery disease; TGCT cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs2346177 0.875 rs12986585 chr2:46644121 T/A cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.77 -0.39 5.07e-6 HDL cholesterol; TGCT cis rs9926296 0.656 rs2376884 chr16:89826922 C/T cg04287289 chr16:89883240 FANCA 0.66 6.63 0.51 9.24e-10 Vitiligo; TGCT cis rs9926296 0.568 rs417323 chr16:89746277 T/G cg26513180 chr16:89883248 FANCA -0.66 -6.25 -0.49 6.16e-9 Vitiligo; TGCT cis rs7829975 0.681 rs2271342 chr8:8643938 C/T cg06636001 chr8:8085503 FLJ10661 0.71 6.29 0.49 4.94e-9 Mood instability; TGCT trans rs916888 0.821 rs199525 chr17:44847834 T/G cg10053473 chr17:62856997 LRRC37A3 -0.45 -6.78 -0.52 4.41e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12135062 0.901 rs2651928 chr1:3101722 C/T cg00254258 chr1:3105189 PRDM16 -0.34 -5.57 -0.45 1.52e-7 Migraine; TGCT cis rs11785400 0.793 rs13255558 chr8:143748080 C/T cg10596483 chr8:143751796 JRK 0.55 5.34 0.43 4.27e-7 Schizophrenia; TGCT cis rs12681288 0.578 rs10503154 chr8:969343 C/G cg04851639 chr8:1020857 NA -0.32 -5.5 -0.44 2.06e-7 Schizophrenia; TGCT cis rs12477438 0.520 rs36071868 chr2:99737120 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.0 0.63 3.26e-15 Chronic sinus infection; TGCT cis rs4746059 0.516 rs12777075 chr10:72471772 A/G cg03087610 chr10:71892362 AIFM2 -0.5 -4.54 -0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7940866 0.804 rs10894289 chr11:130808685 C/T cg05962950 chr11:130786565 SNX19 0.67 6.64 0.51 8.71e-10 Schizophrenia; TGCT cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg03264133 chr6:25882463 NA -0.65 -5.81 -0.46 5.01e-8 Intelligence (multi-trait analysis); TGCT cis rs17601876 0.778 rs11632926 chr15:51564226 G/A cg19946085 chr15:51559439 CYP19A1 -0.34 -5.04 -0.41 1.59e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg08439880 chr3:133502540 NA -0.27 -4.82 -0.4 4.09e-6 Iron status biomarkers; TGCT cis rs2762353 0.935 rs1183200 chr6:25818646 G/C cg03264133 chr6:25882463 NA -0.53 -5.53 -0.44 1.81e-7 Blood metabolite levels; TGCT cis rs12136530 0.625 rs12726614 chr1:19730957 G/C cg24875000 chr1:19041556 PAX7 -0.26 -4.57 -0.38 1.15e-5 Lead levels in blood; TGCT cis rs1532993 0.518 rs6532691 chr4:98632582 A/T cg05340658 chr4:99064831 C4orf37 -0.4 -4.91 -0.4 2.77e-6 Post bronchodilator FEV1/FVC ratio; TGCT trans rs9985766 1.000 rs4339189 chr4:151024575 G/C cg02993991 chr19:4064177 ZBTB7A 0.57 6.7 0.52 6.59e-10 Coronary artery disease;Myocardial infarction; TGCT cis rs9911578 0.967 rs4132925 chr17:56938016 C/G cg05425664 chr17:57184151 TRIM37 0.64 6.38 0.5 3.19e-9 Intelligence (multi-trait analysis); TGCT cis rs17102423 0.558 rs11628664 chr14:65615651 C/T cg11161011 chr14:65562177 MAX -0.41 -5.66 -0.45 9.83e-8 Obesity-related traits; TGCT cis rs832540 0.931 rs702679 chr5:56221328 A/G cg24531977 chr5:56204891 C5orf35 -0.52 -5.19 -0.42 8.26e-7 Coronary artery disease; TGCT cis rs13191362 0.507 rs2023037 chr6:163120385 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.55 5.25 0.43 6.46e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg03760483 chr17:6899297 ALOX12 0.48 5.5 0.44 2.11e-7 Tonsillectomy; TGCT cis rs116095464 0.558 rs10055993 chr5:264296 A/C cg22857025 chr5:266934 NA -0.35 -6.91 -0.53 2.25e-10 Breast cancer; TGCT cis rs17253792 0.822 rs8009608 chr14:56062590 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6089829 0.926 rs6062395 chr20:61667904 A/G cg08045932 chr20:61659980 NA 0.47 8.85 0.62 7.34e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs9549260 0.755 rs4943800 chr13:41216831 A/G cg21288729 chr13:41239152 FOXO1 0.99 10.37 0.68 1.56e-18 Red blood cell count; TGCT cis rs4819052 0.851 rs2838849 chr21:46671027 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13427251 0.868 rs1901284 chr2:100146040 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.54 4.98 0.41 2.04e-6 Chronic sinus infection; TGCT cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg06238570 chr21:40685208 BRWD1 -0.62 -6.17 -0.48 8.82e-9 Menarche (age at onset); TGCT cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg07636037 chr3:49044803 WDR6 0.83 8.44 0.6 6.88e-14 Menarche (age at onset); TGCT cis rs929354 0.935 rs1182392 chr7:157036200 C/T cg05182265 chr7:156933206 UBE3C 0.31 6.4 0.5 2.93e-9 Body mass index; TGCT cis rs769267 0.930 rs10422819 chr19:19643028 C/A cg08509172 chr19:19383838 TM6SF2 -0.35 -4.51 -0.38 1.46e-5 Tonsillectomy; TGCT cis rs6089829 0.962 rs6122352 chr20:61668284 T/C cg03213289 chr20:61660250 NA 0.69 9.94 0.67 1.81e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs2839186 0.504 rs4347941 chr21:47938239 T/C cg10657630 chr21:48055338 PRMT2 0.49 4.73 0.39 5.91e-6 Testicular germ cell tumor; TGCT cis rs35146811 0.735 rs858512 chr7:99824453 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs7267979 0.966 rs2387885 chr20:25415224 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467711 0.790 rs13198716 chr6:26582035 A/G cg16898833 chr6:26189333 HIST1H4D -1.37 -6.2 -0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs2115630 0.967 rs8027779 chr15:85255385 T/C cg11189052 chr15:85197271 WDR73 -0.67 -6.57 -0.51 1.25e-9 P wave terminal force; TGCT cis rs2562456 0.917 rs10420016 chr19:21688602 C/G cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs6968419 0.674 rs1918911 chr7:115906748 G/T cg25274503 chr7:116140128 CAV2 0.56 4.48 0.37 1.68e-5 Intraocular pressure; TGCT cis rs797680 0.894 rs7418101 chr1:93756192 G/A cg17826107 chr1:92977322 EVI5 0.23 5.12 0.42 1.15e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.28 0.49 5.19e-9 Schizophrenia; TGCT cis rs9911578 1.000 rs9901181 chr17:56964271 C/T cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs4494114 0.967 rs3814342 chr1:39325983 A/G cg25970120 chr1:39325951 RRAGC -0.6 -6.43 -0.5 2.52e-9 Blood protein levels; TGCT cis rs8028182 0.636 rs7495610 chr15:75784441 T/C cg20655648 chr15:75932815 IMP3 0.59 4.49 0.37 1.58e-5 Sudden cardiac arrest; TGCT cis rs61897795 0.657 rs174587 chr11:61612830 C/T cg19610905 chr11:61596333 FADS2 -0.8 -6.19 -0.49 8.16e-9 Neutrophil count;Sum basophil neutrophil counts; TGCT cis rs853679 0.546 rs175597 chr6:27810626 T/C cg10876282 chr6:28092338 ZSCAN16 0.74 4.44 0.37 1.98e-5 Depression; TGCT cis rs7949030 0.653 rs2849030 chr11:62366986 G/A cg13298116 chr11:62369859 EML3;MTA2 -0.62 -9.24 -0.64 8.81e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3771570 0.901 rs3771585 chr2:242400723 G/A cg21155796 chr2:242212141 HDLBP 0.89 6.82 0.52 3.55e-10 Prostate cancer; TGCT cis rs10838634 0.803 rs7105217 chr11:46838838 T/A cg18332754 chr11:46939436 LRP4 0.89 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs2239815 0.515 rs9625591 chr22:29232564 A/G cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg21724239 chr8:58056113 NA 0.38 5.18 0.42 8.82e-7 Developmental language disorder (linguistic errors); TGCT cis rs4689388 0.926 rs1801214 chr4:6303022 C/T cg14416269 chr4:6271139 WFS1 0.39 5.2 0.42 8.1e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6988636 0.710 rs59229243 chr8:124155673 G/A cg27053337 chr8:124217698 FAM83A 0.72 5.08 0.42 1.34e-6 Urinary uromodulin levels; TGCT cis rs59698941 0.550 rs11739194 chr5:132201230 T/C cg27099455 chr5:132201840 GDF9;UQCRQ 0.3 5.02 0.41 1.75e-6 Apolipoprotein A-IV levels; TGCT cis rs7927771 0.832 rs10838704 chr11:47424717 T/C cg10139015 chr11:47448256 PSMC3 0.52 4.44 0.37 1.97e-5 Subjective well-being; TGCT cis rs5769765 1.000 rs761879 chr22:50241210 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.38 -5.65 -0.45 1.03e-7 Schizophrenia; TGCT cis rs9611565 0.592 rs5751101 chr22:41828111 C/T cg03806693 chr22:41940476 POLR3H 1.12 13.0 0.76 6.43e-25 Vitiligo; TGCT cis rs2072499 0.966 rs1060604 chr1:156184268 T/C cg25208724 chr1:156163844 SLC25A44 1.11 12.73 0.75 2.98e-24 Testicular germ cell tumor; TGCT cis rs1008375 0.931 rs7435102 chr4:17571480 C/G cg16339924 chr4:17578868 LAP3 0.82 7.13 0.54 7.32e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs6088580 0.634 rs6059835 chr20:33020141 A/G cg06115741 chr20:33292138 TP53INP2 0.55 4.81 0.4 4.24e-6 Glomerular filtration rate (creatinine); TGCT cis rs1570884 0.516 rs2094108 chr13:50171550 G/A cg03651054 chr13:50194643 NA 0.32 5.26 0.43 6.06e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs453301 0.686 rs6601280 chr8:8909236 A/T cg06636001 chr8:8085503 FLJ10661 0.7 6.06 0.48 1.52e-8 Joint mobility (Beighton score); TGCT cis rs1801251 1.000 rs12474040 chr2:233615345 T/G cg25237894 chr2:233734115 C2orf82 0.32 5.68 0.45 8.93e-8 Coronary artery disease; TGCT cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs6469804 0.557 rs4295687 chr8:120058346 A/T cg17171407 chr8:119960777 TNFRSF11B 0.27 4.72 0.39 6.29e-6 Bone mineral density (spine); TGCT cis rs6430585 0.528 rs3099429 chr2:136655582 T/A cg07169764 chr2:136633963 MCM6 1.17 10.98 0.7 5.11e-20 Corneal structure; TGCT cis rs854765 0.547 rs6502633 chr17:17941037 G/C cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.94e-6 Total body bone mineral density; TGCT cis rs2303745 0.589 rs7246262 chr19:17392483 C/G cg02221750 chr19:17393354 ANKLE1 -0.48 -6.27 -0.49 5.46e-9 Systemic lupus erythematosus; TGCT cis rs56036086 1.000 rs73187250 chr22:50634552 G/A cg01548456 chr22:50352384 NA 0.37 4.82 0.4 4.17e-6 Platelet count;Plateletcrit; TGCT cis rs4665809 0.838 rs2243834 chr2:26357748 A/C cg25036284 chr2:26402008 FAM59B 0.5 4.72 0.39 6.25e-6 Gut microbiome composition (summer); TGCT cis rs6684514 1.000 rs12130361 chr1:156260301 C/T cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7940866 0.646 rs10894293 chr11:130824213 C/T cg05962950 chr11:130786565 SNX19 -0.76 -7.5 -0.56 1.09e-11 Schizophrenia; TGCT cis rs9467773 1.000 rs6926629 chr6:26499903 T/C cg09904177 chr6:26538194 HMGN4 0.64 6.49 0.5 1.89e-9 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.735 rs858506 chr7:99820050 T/C cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs7568458 0.905 rs59877521 chr2:85759494 C/T cg17127132 chr2:85788382 GGCX 0.73 6.97 0.53 1.64e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7552404 0.731 rs10873808 chr1:76406767 T/C cg03433033 chr1:76189801 ACADM 0.78 7.49 0.56 1.12e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2980439 0.818 rs2948300 chr8:8106508 C/T cg08975724 chr8:8085496 FLJ10661 0.6 5.47 0.44 2.36e-7 Neuroticism; TGCT cis rs7647973 0.593 rs28535523 chr3:49848414 C/T cg03060546 chr3:49711283 APEH -0.67 -5.93 -0.47 2.82e-8 Menarche (age at onset); TGCT cis rs782590 0.902 rs782601 chr2:55848244 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.91 0.53 2.23e-10 Metabolic syndrome; TGCT cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs17826219 0.636 rs8080829 chr17:29058730 C/T cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Body mass index; TGCT cis rs7647973 0.560 rs77473999 chr3:49777660 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.59 -0.38 1.08e-5 Menarche (age at onset); TGCT cis rs6570726 0.791 rs12208812 chr6:145900924 T/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.58 -0.38 1.13e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2688608 0.592 rs7080579 chr10:75504029 T/A cg04320760 chr10:75533139 FUT11 -0.4 -6.06 -0.48 1.49e-8 Inflammatory bowel disease; TGCT cis rs17376456 0.757 rs1031424 chr5:93139706 G/C cg21475434 chr5:93447410 FAM172A 0.62 4.67 0.39 7.58e-6 Diabetic retinopathy; TGCT cis rs912057 0.671 rs1294417 chr6:6741932 T/C cg06612196 chr6:6737390 NA 0.48 7.07 0.54 1.01e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs10883723 0.810 rs61873733 chr10:104251458 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs806215 0.526 rs882694 chr7:127496768 A/G cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.46e-6 Type 2 diabetes; TGCT trans rs8073060 0.586 rs6505484 chr17:33993152 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs3087591 0.960 rs12949230 chr17:29461899 G/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.3 0.55 3.03e-11 Hip circumference; TGCT cis rs13088645 0.532 rs7623580 chr3:134164345 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.67 6.38 0.5 3.21e-9 Coronary artery disease; TGCT cis rs208520 0.770 rs2153941 chr6:66885521 A/T cg07460842 chr6:66804631 NA -0.9 -9.36 -0.64 4.37e-16 Exhaled nitric oxide output; TGCT cis rs10927875 0.722 rs1763606 chr1:16338282 A/G cg14742211 chr1:16348397 CLCNKA 0.19 4.53 0.38 1.37e-5 Dilated cardiomyopathy; TGCT cis rs6582630 0.555 rs11182422 chr12:38522833 A/G cg13010199 chr12:38710504 ALG10B 0.6 4.99 0.41 2.02e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs295140 0.605 rs34693942 chr2:201184348 T/C cg04283868 chr2:201171347 SPATS2L 0.49 4.69 0.39 7.21e-6 QT interval; TGCT cis rs10501293 0.709 rs10742664 chr11:43034588 G/A cg03447554 chr11:43094025 NA 0.44 6.29 0.49 5.05e-9 Cognitive performance; TGCT cis rs2228479 0.717 rs2286392 chr16:89809549 A/G cg04287289 chr16:89883240 FANCA 0.74 4.44 0.37 1.99e-5 Skin colour saturation; TGCT cis rs478304 0.654 rs10896029 chr11:65452952 C/T cg27068330 chr11:65405492 SIPA1 -1.0 -11.14 -0.71 2.07e-20 Acne (severe); TGCT trans rs2727020 0.595 rs10769583 chr11:49483193 G/A cg15704280 chr7:45808275 SEPT13 -0.74 -8.52 -0.61 4.54e-14 Coronary artery disease; TGCT cis rs17206232 0.534 rs13165273 chr5:64693051 T/C cg09571848 chr5:64330935 NA -0.31 -4.59 -0.38 1.05e-5 Schizophrenia; TGCT cis rs208515 0.525 rs12214310 chr6:66666308 A/G cg07460842 chr6:66804631 NA 0.85 8.73 0.62 1.41e-14 Exhaled nitric oxide levels; TGCT cis rs17345786 0.906 rs56171035 chr3:101111108 G/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs2637266 1.000 rs3923670 chr10:78375001 C/G cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs12477438 0.677 rs12475034 chr2:99699464 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.82 -7.18 -0.54 5.51e-11 Chronic sinus infection; TGCT cis rs1552244 0.882 rs13063098 chr3:10009919 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.62 -0.51 9.56e-10 Alzheimer's disease; TGCT cis rs4478858 0.735 rs4949382 chr1:31776731 A/G cg00250761 chr1:31883323 NA -0.27 -4.94 -0.41 2.43e-6 Alcohol dependence; TGCT cis rs2204008 0.580 rs11520047 chr12:38051778 T/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs4788570 0.566 rs9989376 chr16:71498983 C/T cg06353428 chr16:71660113 MARVELD3 -1.19 -7.74 -0.57 3.06e-12 Intelligence (multi-trait analysis); TGCT cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg01411255 chr17:61851458 DDX42;CCDC47 1.11 14.12 0.79 1.4e-27 Height; TGCT cis rs17376456 0.877 rs10476599 chr5:93383423 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg18538332 chr22:24372958 LOC391322 0.85 9.87 0.66 2.55e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9921338 0.961 rs9302459 chr16:11420339 G/T cg00044050 chr16:11439710 C16orf75 0.9 6.67 0.51 7.6e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs1031925 0.640 rs6445959 chr3:51772347 C/T cg10583097 chr3:51429234 RBM15B 0.52 4.96 0.41 2.26e-6 Melanoma; TGCT cis rs6831352 0.693 rs2602875 chr4:100039495 C/G cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs72781680 0.583 rs6731333 chr2:24113354 C/T cg08917208 chr2:24149416 ATAD2B 0.78 4.95 0.41 2.4e-6 Lymphocyte counts; TGCT cis rs6964587 1.000 rs6953515 chr7:91658620 C/T cg17063962 chr7:91808500 NA 0.91 9.88 0.66 2.45e-17 Breast cancer; TGCT cis rs523522 0.962 rs1050187 chr12:120902111 A/G cg12219531 chr12:120966889 COQ5 -0.83 -7.33 -0.55 2.6e-11 High light scatter reticulocyte count; TGCT cis rs3806843 0.547 rs183679 chr5:140271017 C/T cg07102913 chr5:140593443 PCDHB13 0.47 4.52 0.38 1.42e-5 Depressive symptoms (multi-trait analysis); TGCT trans rs66573146 1.000 rs56074877 chr4:6990374 C/T cg07817883 chr1:32538562 TMEM39B 1.3 6.83 0.52 3.41e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs62064224 0.614 rs728718 chr17:30708960 T/G cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.77e-6 Schizophrenia; TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg07157834 chr1:205819609 PM20D1 0.45 7.34 0.55 2.47e-11 Menarche (age at onset); TGCT cis rs10089 0.953 rs1012851 chr5:127360241 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.91 0.53 2.29e-10 Ileal carcinoids; TGCT cis rs40363 0.645 rs250627 chr16:3527050 G/A cg05754148 chr16:3507555 NAT15 0.41 4.94 0.41 2.46e-6 Tuberculosis; TGCT cis rs1580019 0.922 rs1376289 chr7:32486980 C/G cg06627557 chr7:32535165 LSM5;AVL9 -0.9 -7.86 -0.58 1.55e-12 Cognitive ability; TGCT cis rs72781680 0.898 rs116113042 chr2:23960194 G/T cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs28595532 1.000 rs11931194 chr4:119631160 C/T cg21605333 chr4:119757512 SEC24D 1.36 7.4 0.55 1.82e-11 Cannabis dependence symptom count; TGCT cis rs4689388 0.853 rs13108780 chr4:6294630 A/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs10435719 0.834 rs6985792 chr8:11795335 T/C cg15556689 chr8:8085844 FLJ10661 0.75 7.18 0.54 5.55e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs11718455 0.585 rs11719257 chr3:43914854 A/T cg08738300 chr3:44038990 NA 0.66 4.52 0.38 1.44e-5 Coronary artery disease; TGCT cis rs4499344 0.633 rs166310 chr19:33155187 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg23131131 chr22:24373011 LOC391322 0.57 4.52 0.38 1.41e-5 S-phenylmercapturic acid levels in smokers; TGCT cis rs11122272 0.735 rs2486733 chr1:231531465 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -6.35 -0.5 3.66e-9 Hemoglobin concentration; TGCT cis rs3935685 0.874 rs35761651 chr15:78003069 G/T cg03457338 chr15:78040120 NA -0.23 -5.79 -0.46 5.55e-8 Intelligence (multi-trait analysis); TGCT cis rs6964587 0.773 rs38793 chr7:92027187 A/G cg17063962 chr7:91808500 NA -0.83 -8.02 -0.58 6.71e-13 Breast cancer; TGCT cis rs1056053 0.514 rs1056051 chr6:166571579 T/G cg17219086 chr6:166541254 NA -0.2 -4.58 -0.38 1.1e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT cis rs769267 0.930 rs4808967 chr19:19640524 A/G cg03709012 chr19:19516395 GATAD2A 0.74 6.09 0.48 1.28e-8 Tonsillectomy; TGCT cis rs2066819 0.892 rs75274818 chr12:56627619 A/G cg26714650 chr12:56694279 CS -1.42 -5.7 -0.46 8.43e-8 Psoriasis vulgaris; TGCT trans rs4332037 0.713 rs56093134 chr7:1973970 C/T cg10840412 chr1:235813424 GNG4 0.98 7.54 0.56 8.81e-12 Bipolar disorder; TGCT cis rs9467711 0.606 rs9379859 chr6:26369549 C/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6430585 0.583 rs1435577 chr2:136624947 C/G cg07169764 chr2:136633963 MCM6 1.24 12.25 0.74 4.19e-23 Corneal structure; TGCT cis rs1729951 0.575 rs361245 chr3:136695706 A/G cg21827317 chr3:136751795 NA 0.39 5.52 0.44 1.86e-7 Neuroticism; TGCT cis rs6089829 0.816 rs6062397 chr20:61668268 A/G cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs4886920 0.666 rs11629621 chr15:78080737 C/G cg03457338 chr15:78040120 NA -0.18 -4.47 -0.37 1.74e-5 Neuroticism; TGCT cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg27286337 chr10:134555280 INPP5A 0.41 5.16 0.42 9.57e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11785400 0.762 rs1137522 chr8:143739020 A/C cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs4455778 0.580 rs7804423 chr7:49118270 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs6570726 0.791 rs414297 chr6:145887556 C/T cg23711669 chr6:146136114 FBXO30 0.85 9.18 0.64 1.18e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7914558 0.966 rs3758543 chr10:104944744 C/G cg15744005 chr10:104629667 AS3MT -0.39 -4.73 -0.39 5.91e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7772486 0.846 rs2748496 chr6:146321829 T/A cg05347473 chr6:146136440 FBXO30 0.49 4.7 0.39 6.88e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg04025307 chr7:1156635 C7orf50 0.22 4.91 0.4 2.86e-6 Longevity;Endometriosis; TGCT cis rs6684514 1.000 rs67034206 chr1:156270260 C/T cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7172809 0.548 rs17385352 chr15:77651305 A/G cg22256960 chr15:77711686 NA -0.51 -4.81 -0.4 4.29e-6 Glucose homeostasis traits; TGCT cis rs2228479 0.702 rs78331410 chr16:89917775 C/T cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs7474896 0.522 rs117157955 chr10:37984164 G/T cg25427524 chr10:38739819 LOC399744 -0.31 -4.83 -0.4 3.98e-6 Obesity (extreme); TGCT cis rs7731657 0.537 rs4705924 chr5:130210792 G/A cg08523029 chr5:130500466 HINT1 -0.59 -4.9 -0.4 2.96e-6 Fasting plasma glucose; TGCT cis rs3820068 0.580 rs12082523 chr1:16005792 A/G cg17385448 chr1:15911702 AGMAT -0.35 -4.96 -0.41 2.27e-6 Systolic blood pressure; TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.67 0.39 7.57e-6 Prudent dietary pattern; TGCT cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg17054783 chr10:134559939 INPP5A 0.26 5.0 0.41 1.89e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4076764 0.958 rs10917748 chr1:163400377 T/C cg24596788 chr1:163392923 NA -0.17 -4.74 -0.39 5.85e-6 Motion sickness; TGCT cis rs1005224 0.853 rs9323616 chr14:76151697 T/C cg04684003 chr14:76127793 TTLL5;C14orf1 -0.67 -5.96 -0.47 2.45e-8 Large artery stroke; TGCT cis rs6582630 0.519 rs80226845 chr12:38528231 C/A cg26384229 chr12:38710491 ALG10B 0.86 7.78 0.57 2.47e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs10489202 0.657 rs3767478 chr1:168069626 G/A cg24449463 chr1:168025552 DCAF6 -0.52 -5.45 -0.44 2.58e-7 Schizophrenia; TGCT cis rs826838 0.967 rs1684413 chr12:39128704 G/A cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs7772486 0.754 rs697054 chr6:146003770 C/T cg13319975 chr6:146136371 FBXO30 -0.54 -4.99 -0.41 1.96e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7149242 0.849 rs10146962 chr14:101170540 A/G cg18089426 chr14:101175970 NA 0.4 4.84 0.4 3.79e-6 Platelet count; TGCT cis rs2762353 0.574 rs4419666 chr6:25693274 C/T cg07061783 chr6:25882402 NA 0.73 7.21 0.54 4.76e-11 Blood metabolite levels; TGCT cis rs17767294 0.708 rs6908688 chr6:27886051 A/G cg08851530 chr6:28072375 NA 1.33 6.57 0.51 1.25e-9 Parkinson's disease; TGCT cis rs854765 0.547 rs4459604 chr17:17888549 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.22 0.59 2.35e-13 Total body bone mineral density; TGCT cis rs3087591 0.614 rs3785955 chr17:29647802 C/T cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT cis rs7572733 0.534 rs770662 chr2:198729283 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs6815814 0.861 rs17616434 chr4:38812876 T/C cg06935464 chr4:38784597 TLR10 0.29 4.55 0.38 1.26e-5 Breast cancer; TGCT cis rs3806843 0.612 rs246075 chr5:140300557 T/C cg07102913 chr5:140593443 PCDHB13 -0.46 -4.54 -0.38 1.3e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT trans rs28735056 1.000 rs56197868 chr18:77636077 C/T cg05926928 chr17:57297772 GDPD1 -0.71 -7.64 -0.57 5e-12 Schizophrenia; TGCT cis rs319204 1.000 rs2446369 chr5:146233790 A/T cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs36051895 0.626 rs3780368 chr9:5093188 G/C cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs4746818 1.000 rs7476357 chr10:70935660 G/A cg04149295 chr10:70884716 VPS26A 0.78 5.32 0.43 4.7e-7 Left atrial antero-posterior diameter; TGCT cis rs6831256 1.000 rs6831256 chr4:3473139 A/G cg13455623 chr4:3480656 DOK7 0.25 4.51 0.38 1.5e-5 LDL cholesterol;Triglyceride levels;Triglycerides;Cholesterol, total; TGCT cis rs2274273 0.682 rs1201378 chr14:55493408 A/G cg01923255 chr14:55878535 KIAA0831 -0.56 -4.88 -0.4 3.26e-6 Protein biomarker; TGCT cis rs514406 0.861 rs4926577 chr1:53226788 C/A cg16325326 chr1:53192061 ZYG11B -0.71 -8.82 -0.62 8.9e-15 Monocyte count; TGCT cis rs611744 0.967 rs677288 chr8:109177539 T/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs12615966 0.872 rs72830429 chr2:105367977 T/C cg16465502 chr2:105461796 NA 0.75 4.65 0.39 8.22e-6 Pancreatic cancer; TGCT cis rs694739 0.654 rs10897488 chr11:64140806 T/C cg02228329 chr11:64053129 BAD;GPR137 0.7 6.8 0.52 4.02e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs796364 1.000 rs281762 chr2:200799201 C/G cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs1552244 0.882 rs13063098 chr3:10009919 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.81 0.46 4.88e-8 Alzheimer's disease; TGCT cis rs7267979 1.000 rs6107046 chr20:25442049 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11098499 0.909 rs10014719 chr4:120320715 G/A cg09307838 chr4:120376055 NA 0.67 6.37 0.5 3.35e-9 Corneal astigmatism; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg10819733 chr22:24237672 NA -0.29 -4.7 -0.39 6.71e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs3780486 0.846 rs10971438 chr9:33180308 A/G cg20290983 chr6:43655470 MRPS18A 1.08 11.4 0.72 5.03e-21 IgG glycosylation; TGCT cis rs4478037 0.558 rs60462824 chr3:33085929 T/C cg19404215 chr3:33155277 CRTAP 1.09 5.15 0.42 9.92e-7 Major depressive disorder; TGCT cis rs7095607 1.000 rs7900891 chr10:69953042 G/A cg18986048 chr10:69913749 MYPN 0.46 5.08 0.41 1.37e-6 Lung function (FVC); TGCT cis rs2070488 0.804 rs2276541 chr3:38512779 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.9 0.58 1.26e-12 Electrocardiographic conduction measures; TGCT cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg00343986 chr7:65444356 GUSB 0.22 5.32 0.43 4.62e-7 Calcium levels; TGCT cis rs77372450 0.551 rs62387681 chr5:157107531 G/C cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.51e-6 Bipolar disorder (body mass index interaction); TGCT cis rs2180341 1.000 rs9385419 chr6:127597591 A/G cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs11874712 0.563 rs2850646 chr18:43674646 C/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.49 4.9 0.4 2.91e-6 Migraine - clinic-based; TGCT cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg11890956 chr21:40555474 PSMG1 1.11 12.48 0.75 1.21e-23 Cognitive function; TGCT cis rs939574 0.790 rs2385397 chr2:220087796 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.14 -6.06 -0.48 1.49e-8 Platelet distribution width; TGCT cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg27588902 chr6:42928151 GNMT -0.56 -6.9 -0.53 2.41e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1218582 0.772 rs6683557 chr1:154852307 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.96 -0.53 1.72e-10 Prostate cancer; TGCT cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg02503808 chr4:7069936 GRPEL1 1.01 9.19 0.64 1.16e-15 Monocyte percentage of white cells; TGCT cis rs7255045 0.788 rs2290689 chr19:12958360 T/C cg23899408 chr19:12877188 HOOK2 -0.6 -5.03 -0.41 1.67e-6 Mean corpuscular volume; TGCT cis rs1005277 0.638 rs1005278 chr10:38218748 G/A cg25427524 chr10:38739819 LOC399744 0.31 4.79 0.4 4.68e-6 Extrinsic epigenetic age acceleration; TGCT cis rs7507204 0.767 rs12982509 chr19:3412057 C/T cg08380311 chr19:3435252 NFIC -0.94 -8.13 -0.59 3.71e-13 Height; TGCT trans rs1005277 0.579 rs2474588 chr10:38420870 A/G cg27523141 chr10:43048294 ZNF37B 0.72 8.36 0.6 1.09e-13 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT trans rs77457752 0.690 rs10123356 chr9:13912564 T/C cg12973904 chr7:149457885 NA 0.46 7.39 0.55 1.88e-11 Breast cancer; TGCT trans rs8073060 0.586 rs225286 chr17:33930458 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.04 -0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs10479542 0.721 rs6894113 chr5:178974789 G/C cg21226059 chr5:178986404 RUFY1 0.47 5.2 0.42 7.83e-7 Lung cancer; TGCT cis rs910316 0.737 rs175071 chr14:75498177 A/G cg08847533 chr14:75593920 NEK9 -0.82 -8.58 -0.61 3.25e-14 Height; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg18538332 chr22:24372958 LOC391322 -0.76 -6.61 -0.51 1.03e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7726839 0.561 rs6555357 chr5:560923 A/G cg09021430 chr5:549028 NA -0.41 -5.79 -0.46 5.55e-8 Obesity-related traits; TGCT cis rs9660180 0.967 rs61422524 chr1:1767565 C/A cg23982607 chr1:1823379 GNB1 -0.56 -8.38 -0.6 9.54e-14 Body mass index; TGCT cis rs4325129 0.705 rs7514139 chr1:159498909 C/T cg07417683 chr1:159440267 NA 0.37 4.64 0.38 8.54e-6 Obesity-related traits; TGCT cis rs3862030 0.810 rs11593710 chr10:104328719 A/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.36 -0.43 3.84e-7 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs17401966 0.838 rs1538557 chr1:10297230 T/C cg19773385 chr1:10388646 KIF1B -0.21 -4.57 -0.38 1.14e-5 Hepatocellular carcinoma; TGCT cis rs11514810 1.000 rs4076699 chr7:1435521 C/T cg24899294 chr7:1481343 MICALL2 -0.45 -5.49 -0.44 2.18e-7 Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder; TGCT cis rs2239815 0.515 rs9625595 chr22:29238913 C/T cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs6463523 0.933 rs4724821 chr7:762544 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.86 12.13 0.74 8.29e-23 Subjective well-being; TGCT cis rs514406 0.621 rs881198 chr1:53196440 C/T cg24675658 chr1:53192096 ZYG11B 0.85 10.64 0.69 3.5e-19 Monocyte count; TGCT cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg27454412 chr7:1067447 C7orf50 0.58 4.54 0.38 1.3e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs1801251 1.000 rs283476 chr2:233650168 A/G cg25237894 chr2:233734115 C2orf82 0.26 4.45 0.37 1.89e-5 Coronary artery disease; TGCT cis rs6920965 0.507 rs9385389 chr6:126215486 G/C cg05901451 chr6:126070800 HEY2 -0.67 -6.45 -0.5 2.26e-9 High light scatter reticulocyte count; TGCT cis rs6964587 0.967 rs28594877 chr7:91644070 C/T cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs6921919 0.525 rs9468361 chr6:28346318 T/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10501293 0.746 rs1544871 chr11:43054122 T/C cg03447554 chr11:43094025 NA 0.45 6.58 0.51 1.2e-9 Cognitive performance; TGCT cis rs3892630 0.824 rs2287884 chr19:33321447 A/G cg22980127 chr19:33182716 NUDT19 0.72 5.22 0.42 7.45e-7 Red blood cell traits; TGCT cis rs711245 0.670 rs7560321 chr2:36822318 C/G cg01206211 chr2:36825736 FEZ2 -0.31 -5.18 -0.42 8.55e-7 Height; TGCT cis rs1682361 1 rs1682361 chr3:136734014 G/C cg21827317 chr3:136751795 NA 0.58 9.52 0.65 1.81e-16 Schizophrenia; TGCT cis rs11098499 0.691 rs10028773 chr4:120265259 C/G cg09307838 chr4:120376055 NA -0.56 -5.52 -0.44 1.9e-7 Corneal astigmatism; TGCT cis rs2839186 0.843 rs17182671 chr21:47696238 T/C cg13732083 chr21:47605072 C21orf56 0.34 4.51 0.38 1.51e-5 Testicular germ cell tumor; TGCT cis rs7172809 0.561 rs28712147 chr15:77844661 C/G cg22256960 chr15:77711686 NA -0.47 -4.66 -0.39 7.96e-6 Glucose homeostasis traits; TGCT cis rs8033133 0.560 rs11161166 chr15:25324677 A/T cg14481604 chr15:25334117 SNORD116-22 0.21 4.61 0.38 9.73e-6 Blood osmolality (transformed sodium); TGCT cis rs6977660 0.714 rs2390156 chr7:19786138 A/T cg05791153 chr7:19748676 TWISTNB 0.84 4.71 0.39 6.52e-6 Thyroid stimulating hormone; TGCT cis rs7826238 0.543 rs2976908 chr8:8345774 T/G cg08975724 chr8:8085496 FLJ10661 0.53 4.76 0.39 5.32e-6 Systolic blood pressure; TGCT cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg20607798 chr8:58055168 NA 0.45 4.59 0.38 1.06e-5 Developmental language disorder (linguistic errors); TGCT cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg13683864 chr3:40499215 RPL14 1.17 13.23 0.76 1.88e-25 Renal cell carcinoma; TGCT trans rs7819412 0.505 rs34031674 chr8:10809490 G/C cg15556689 chr8:8085844 FLJ10661 -0.84 -7.59 -0.56 6.55e-12 Triglycerides; TGCT cis rs9611519 0.929 rs4820425 chr22:41431342 C/A cg03806693 chr22:41940476 POLR3H -0.67 -5.79 -0.46 5.32e-8 Neuroticism; TGCT cis rs67385638 0.962 rs2071348 chr11:5264146 T/G cg12559170 chr11:5275217 HBG2 0.49 8.71 0.62 1.6e-14 Hemoglobin levels; TGCT cis rs858239 0.601 rs10255228 chr7:23158863 G/T cg05602783 chr7:23145260 KLHL7 -0.65 -5.47 -0.44 2.4e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT trans rs3780486 1.000 rs3780480 chr9:33163486 G/T cg04842962 chr6:43655489 MRPS18A 1.12 10.81 0.7 1.32e-19 IgG glycosylation; TGCT cis rs10779751 1.000 rs2300092 chr1:11266464 T/C cg08854313 chr1:11322531 MTOR 0.92 10.31 0.68 2.23e-18 Body mass index; TGCT cis rs7727544 0.709 rs441969 chr5:131702120 G/A cg24060327 chr5:131705240 SLC22A5 -0.57 -6.38 -0.5 3.12e-9 Blood metabolite levels; TGCT cis rs79349575 0.783 rs4399576 chr17:47009835 G/A cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs11190604 1.000 rs12219789 chr10:102213778 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs2727020 0.567 rs1164687 chr11:49290669 G/A cg03929089 chr4:120376271 NA 0.71 7.73 0.57 3.16e-12 Coronary artery disease; TGCT cis rs80282103 0.618 rs11818314 chr10:1148157 G/C cg08668510 chr10:1095578 IDI1 1.05 5.31 0.43 4.8e-7 Glomerular filtration rate (creatinine); TGCT cis rs7567389 0.677 rs11680949 chr2:128123562 C/G cg09760422 chr2:128146352 NA 0.34 4.45 0.37 1.87e-5 Self-rated health; TGCT cis rs11792861 0.591 rs11791855 chr9:111684139 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.69 8.23 0.59 2.2e-13 Menarche (age at onset); TGCT cis rs7568458 0.811 rs1446668 chr2:85764960 G/T cg17127132 chr2:85788382 GGCX 0.64 5.96 0.47 2.47e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7647973 0.710 rs1491983 chr3:49639803 G/T cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs453301 0.686 rs3895823 chr8:8873646 T/C cg11995313 chr8:8860691 ERI1 0.51 4.46 0.37 1.84e-5 Joint mobility (Beighton score); TGCT cis rs7916852 0.618 rs3802520 chr10:28341783 C/T cg15286905 chr10:27530250 ACBD5 -0.6 -5.01 -0.41 1.85e-6 Glaucoma (primary open-angle); TGCT cis rs4836694 0.574 rs67899211 chr9:132935614 G/A cg05251000 chr9:132935664 FREQ 0.55 6.1 0.48 1.25e-8 Alzheimer's disease (cognitive decline); TGCT cis rs6840360 0.593 rs10222925 chr4:152690215 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.2 -0.42 8.05e-7 Intelligence (multi-trait analysis); TGCT cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs11785400 0.793 rs11543967 chr8:143739435 A/G cg10596483 chr8:143751796 JRK -0.55 -5.48 -0.44 2.29e-7 Schizophrenia; TGCT trans rs9951602 0.512 rs9952372 chr18:76656295 A/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.71 0.75 3.32e-24 Obesity-related traits; TGCT cis rs9611565 0.921 rs4822021 chr22:41726053 G/A cg06481639 chr22:41940642 POLR3H -0.54 -4.72 -0.39 6.29e-6 Vitiligo; TGCT cis rs7552404 0.556 rs12124417 chr1:76353294 T/C cg03433033 chr1:76189801 ACADM 0.66 6.55 0.51 1.35e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs854765 0.647 rs9303144 chr17:17977355 T/C cg09796270 chr17:17721594 SREBF1 0.25 4.91 0.4 2.77e-6 Total body bone mineral density; TGCT cis rs112217694 1.000 rs17034020 chr4:104650673 G/A cg24090629 chr4:104641072 TACR3 -1.0 -5.19 -0.42 8.44e-7 Menarche (age at onset); TGCT cis rs7044106 0.791 rs10984994 chr9:123478769 A/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.63 -6.73 -0.52 5.54e-10 Hip circumference adjusted for BMI; TGCT cis rs2637266 0.846 rs2579773 chr10:78402847 A/C cg18941641 chr10:78392320 NA 0.43 5.58 0.45 1.46e-7 Pulmonary function; TGCT cis rs1552244 0.938 rs67667957 chr3:10167264 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 5.92 0.47 2.92e-8 Alzheimer's disease; TGCT cis rs56235845 0.694 rs4532376 chr5:176774403 G/A cg06060754 chr5:176797920 RGS14 0.42 6.57 0.51 1.23e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs7666738 0.830 rs1534319 chr4:98964804 T/C cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs765787 0.530 rs7167389 chr15:45535683 A/G cg24006582 chr15:45444508 DUOX1 -0.27 -5.85 -0.46 4.18e-8 Uric acid levels; TGCT cis rs12134245 0.874 rs34842487 chr1:92021611 C/T cg25838465 chr1:92012736 NA -0.34 -5.64 -0.45 1.08e-7 Breast cancer; TGCT cis rs28595532 0.920 rs116739193 chr4:119771024 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs931608 0.569 rs17461312 chr19:22554107 G/T cg23859931 chr19:22123797 NA -0.61 -4.83 -0.4 3.91e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs8180040 0.764 rs12629262 chr3:47196580 C/T cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT cis rs3812831 0.695 rs7995986 chr13:114938802 A/G cg08824895 chr13:115047677 UPF3A 0.51 5.03 0.41 1.67e-6 Schizophrenia; TGCT cis rs2997447 0.761 rs55815920 chr1:26457662 A/C cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs7666738 0.830 rs62318470 chr4:98925846 A/C cg18180107 chr4:99064573 C4orf37 0.54 4.85 0.4 3.59e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs61867294 0.553 rs7907507 chr10:106711069 A/G cg08000847 chr10:105880925 C10orf78 0.48 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs6089584 0.962 rs6142913 chr20:60566950 A/G cg16423285 chr20:60520624 NA -0.55 -5.8 -0.46 5.24e-8 Body mass index; TGCT cis rs12210905 0.920 rs9368500 chr6:27290981 A/C cg08851530 chr6:28072375 NA 1.29 5.45 0.44 2.65e-7 Hip circumference adjusted for BMI; TGCT cis rs7714584 1.000 rs12656538 chr5:150251380 A/G cg22134413 chr5:150180641 NA 1.17 8.71 0.62 1.61e-14 Crohn's disease; TGCT cis rs6500602 0.701 rs6500614 chr16:4573938 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 6.5 0.5 1.8e-9 Schizophrenia; TGCT cis rs3796352 0.892 rs35076015 chr3:53026366 C/T cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT trans rs3857536 0.566 rs208463 chr6:66913962 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -7.75 -0.57 2.85e-12 Blood trace element (Cu levels); TGCT cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg10117171 chr1:25599238 RHD -0.35 -5.81 -0.46 5.05e-8 Erythrocyte sedimentation rate; TGCT cis rs7953249 0.656 rs2251468 chr12:121405126 A/C cg02403541 chr12:121454288 C12orf43 0.61 5.47 0.44 2.42e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs736408 0.812 rs2071508 chr3:52826846 A/G cg10802521 chr3:52805072 NEK4 0.63 7.18 0.54 5.56e-11 Bipolar disorder; TGCT cis rs6728642 0.908 rs6576996 chr2:97623312 T/C cg26665480 chr2:98280029 ACTR1B -0.91 -5.86 -0.47 3.88e-8 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs1153858 0.943 rs28605551 chr15:45641720 C/T cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs478304 0.654 rs11227260 chr11:65461158 G/T cg27068330 chr11:65405492 SIPA1 -1.0 -11.46 -0.72 3.57e-21 Acne (severe); TGCT cis rs938554 0.513 rs1014290 chr4:10001861 G/A cg11266682 chr4:10021025 SLC2A9 0.53 5.31 0.43 4.95e-7 Blood metabolite levels; TGCT cis rs2070433 1.000 rs2839302 chr21:47952364 G/A cg12379764 chr21:47803548 PCNT 0.51 4.47 0.37 1.71e-5 Lymphocyte counts; TGCT cis rs4642101 0.793 rs12714880 chr3:12832101 G/A cg05775895 chr3:12838266 CAND2 0.78 8.9 0.62 5.77e-15 QRS complex (12-leadsum); TGCT cis rs10779751 0.762 rs6540965 chr1:11325521 C/G cg08854313 chr1:11322531 MTOR -0.79 -8.18 -0.59 2.91e-13 Body mass index; TGCT cis rs4808199 0.895 rs7252888 chr19:19628037 C/T cg03709012 chr19:19516395 GATAD2A 0.91 6.33 0.49 4.1e-9 Nonalcoholic fatty liver disease; TGCT cis rs904251 0.766 rs1757175 chr6:37486694 T/C cg08126542 chr6:37504118 NA -0.45 -6.02 -0.48 1.79e-8 Cognitive performance; TGCT cis rs9677476 0.516 rs6749 chr2:232035429 G/A cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs12477438 0.834 rs11903311 chr2:99701807 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.12 -0.48 1.13e-8 Chronic sinus infection; TGCT cis rs7914558 0.966 rs1890185 chr10:104748718 A/G cg05855489 chr10:104503620 C10orf26 0.51 4.53 0.38 1.39e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2204008 0.652 rs11513964 chr12:37998214 C/G cg26384229 chr12:38710491 ALG10B 0.87 7.79 0.57 2.32e-12 Bladder cancer; TGCT cis rs17490626 0.533 rs5030925 chr10:71211150 A/C cg12610070 chr10:71211762 TSPAN15 -0.6 -6.98 -0.53 1.62e-10 Thrombosis; TGCT cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.96 -10.31 -0.68 2.22e-18 Intelligence (multi-trait analysis); TGCT cis rs10193935 0.792 rs222472 chr2:42662911 C/T cg27598129 chr2:42591480 NA -0.38 -5.41 -0.44 3.09e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6754311 0.593 rs55825471 chr2:136526981 T/A cg07169764 chr2:136633963 MCM6 -0.68 -6.18 -0.49 8.32e-9 Mosquito bite size; TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg25767906 chr1:53392781 SCP2 -0.52 -6.19 -0.49 8.06e-9 Monocyte count; TGCT cis rs4906332 0.966 rs12185021 chr14:103927805 A/G cg26031613 chr14:104095156 KLC1 -0.53 -4.71 -0.39 6.62e-6 Coronary artery disease; TGCT cis rs35417517 1 rs35417517 chr7:91772730 CG/C cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.33e-6 Breast cancer; TGCT trans rs7819412 0.635 rs4841501 chr8:11000976 T/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.79 -0.52 4.2e-10 Triglycerides; TGCT cis rs1887596 0.705 rs11619978 chr13:27167841 A/G cg01312412 chr13:27282625 NA 0.32 5.75 0.46 6.65e-8 Facial morphology (factor 3, length of philtrum); TGCT cis rs2204008 0.806 rs11520229 chr12:38246448 C/A cg13010199 chr12:38710504 ALG10B 0.64 5.01 0.41 1.85e-6 Bladder cancer; TGCT cis rs7119038 0.818 rs11217042 chr11:118682528 G/A cg19308663 chr11:118741387 NA 0.28 5.69 0.45 8.68e-8 Sjögren's syndrome; TGCT cis rs17376456 0.690 rs6892055 chr5:93113023 A/T cg25358565 chr5:93447407 FAM172A 0.91 8.23 0.59 2.21e-13 Diabetic retinopathy; TGCT cis rs2013441 1.000 rs2526462 chr17:20079460 A/T cg23224458 chr17:20280056 CCDC144C -0.37 -4.45 -0.37 1.93e-5 Obesity-related traits; TGCT cis rs9443645 0.901 rs1354832 chr6:79613763 A/G cg09184832 chr6:79620586 NA 0.47 5.15 0.42 9.96e-7 Intelligence (multi-trait analysis); TGCT cis rs72781680 0.898 rs12622290 chr2:23979894 C/G cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs10788264 0.621 rs7907952 chr10:124056774 C/T cg24635736 chr10:124739050 PSTK -0.25 -4.55 -0.38 1.27e-5 Total body bone mineral density; TGCT cis rs9303401 0.659 rs12946852 chr17:57013337 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.68 6.48 0.5 1.94e-9 Cognitive test performance; TGCT cis rs72781680 0.848 rs72798057 chr2:23976731 T/C cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs6893300 0.542 rs3797774 chr5:179193970 C/T cg14593053 chr5:179126677 CANX 0.51 5.9 0.47 3.23e-8 Resting heart rate; TGCT cis rs208520 1.000 rs208536 chr6:66963440 T/C cg07460842 chr6:66804631 NA -0.83 -7.52 -0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs3617 0.625 rs7612624 chr3:52893426 T/C cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6.08e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10927875 0.619 rs7546589 chr1:16129530 A/G cg21385522 chr1:16154831 NA -0.73 -8.75 -0.62 1.27e-14 Dilated cardiomyopathy; TGCT cis rs10751667 0.961 rs7479171 chr11:926809 G/A cg06064525 chr11:970664 AP2A2 -0.31 -6.03 -0.48 1.79e-8 Alzheimer's disease (late onset); TGCT cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg08219700 chr8:58056026 NA 0.4 4.92 0.4 2.67e-6 Developmental language disorder (linguistic errors); TGCT cis rs10089 1.000 rs4835943 chr5:127457569 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs228437 0.609 rs7749956 chr6:134961973 C/T cg09872934 chr6:134495829 SGK1 -0.55 -4.45 -0.37 1.86e-5 Melanoma; TGCT cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg11890956 chr21:40555474 PSMG1 1.12 12.23 0.74 4.65e-23 Cognitive function; TGCT cis rs751728 0.717 rs2281816 chr6:33772335 A/G cg13859433 chr6:33739653 LEMD2 -0.38 -6.54 -0.51 1.48e-9 Crohn's disease; TGCT cis rs13102973 0.965 rs7693757 chr4:135856609 C/T cg14419869 chr4:135874104 NA 0.23 4.57 0.38 1.15e-5 Subjective well-being; TGCT cis rs3782455 0.793 rs77365057 chr12:114404294 G/A cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9911578 0.967 rs2643124 chr17:56741672 T/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs259282 0.669 rs731673 chr19:33132295 A/C cg26639809 chr19:33781782 NA 0.24 4.91 0.4 2.75e-6 Schizophrenia; TGCT cis rs514406 0.505 rs6703127 chr1:53180565 C/T cg22166914 chr1:53195759 ZYG11B 0.45 8.05 0.59 5.76e-13 Monocyte count; TGCT cis rs66573146 1.000 rs6838042 chr4:6973049 G/T cg05069807 chr4:6945702 TBC1D14 0.32 4.59 0.38 1.08e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs9905704 0.647 rs11652713 chr17:57079742 C/T cg12560992 chr17:57184187 TRIM37 0.59 5.64 0.45 1.09e-7 Testicular germ cell tumor; TGCT cis rs2299587 0.554 rs3853531 chr8:17748920 C/T cg01800426 chr8:17659068 MTUS1 0.57 5.08 0.42 1.33e-6 Economic and political preferences; TGCT cis rs8016982 0.674 rs11850714 chr14:81662993 C/G cg01989461 chr14:81687754 GTF2A1 0.78 7.94 0.58 1.06e-12 Schizophrenia; TGCT cis rs4788570 0.615 rs2052584 chr16:71688977 A/G cg06353428 chr16:71660113 MARVELD3 -1.46 -12.33 -0.74 2.69e-23 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.783 rs962272 chr17:46978283 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs9296661 0.832 rs2209638 chr6:51668265 C/T cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs1801251 1.000 rs4973055 chr2:233720283 G/T cg25237894 chr2:233734115 C2orf82 -0.31 -5.45 -0.44 2.6e-7 Coronary artery disease; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg01585852 chr22:24235823 MIF -0.21 -4.56 -0.38 1.23e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs2663905 1.000 rs2663905 chr15:81359137 G/A cg18028999 chr15:81426610 C15orf26 -0.52 -4.97 -0.41 2.18e-6 QT interval (drug interaction); TGCT cis rs11792861 0.926 rs72607163 chr9:111803128 G/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.49 0.37 1.6e-5 Menarche (age at onset); TGCT cis rs2456568 0.867 rs2462750 chr11:93668590 C/T cg16099599 chr11:93583650 C11orf90 -0.39 -4.63 -0.38 9.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1992660 0.523 rs6897022 chr5:40336546 A/G cg01087697 chr5:40835557 RPL37 -0.56 -4.94 -0.41 2.44e-6 Crohn's disease; TGCT cis rs2404602 0.647 rs35940181 chr15:77180019 G/A cg23625390 chr15:77176239 SCAPER -0.39 -5.15 -0.42 9.85e-7 Blood metabolite levels; TGCT cis rs1461503 0.966 rs10790545 chr11:122838350 G/C cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs4689388 0.926 rs4688986 chr4:6285797 C/A cg25554036 chr4:6271136 WFS1 0.56 8.15 0.59 3.3e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1008375 0.966 rs7675735 chr4:17587137 T/A cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs394563 0.591 rs6570964 chr6:149691859 G/A cg11245181 chr6:149772854 ZC3H12D 0.28 4.48 0.37 1.7e-5 Dupuytren's disease; TGCT trans rs17685 0.753 rs10233282 chr7:75790081 C/T cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs17221829 0.899 rs10830367 chr11:89459400 T/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.71 -0.39 6.47e-6 Anxiety in major depressive disorder; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg00024416 chr22:24240387 NA 0.37 6.42 0.5 2.58e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9486715 0.867 rs6568428 chr6:96903604 A/G cg18709589 chr6:96969512 KIAA0776 0.79 7.78 0.57 2.47e-12 Headache; TGCT cis rs910316 0.763 rs175435 chr14:75612025 A/G cg08847533 chr14:75593920 NEK9 0.86 8.79 0.62 1.04e-14 Height; TGCT cis rs6089829 0.962 rs6062778 chr20:61663959 A/G cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs35915560 chr4:98978649 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.25 0.55 3.88e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs7507204 0.530 rs4807470 chr19:3443470 A/T cg08382705 chr11:45687319 CHST1 -0.76 -7.35 -0.55 2.39e-11 Height; TGCT cis rs8031584 0.723 rs711224 chr15:31127921 G/C cg08704250 chr15:31115839 NA 0.44 6.44 0.5 2.33e-9 Huntington's disease progression; TGCT cis rs7267979 1.000 rs1888999 chr20:25291848 C/T cg16686733 chr20:25566563 NINL 0.58 5.95 0.47 2.6e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12620999 0.941 rs2875690 chr2:237977737 G/A cg23555395 chr2:238036564 NA 0.26 4.76 0.39 5.32e-6 Systemic lupus erythematosus; TGCT cis rs9517313 0.565 rs9556978 chr13:99234648 G/A cg07423050 chr13:99094983 FARP1 -0.23 -4.49 -0.37 1.58e-5 Neuroticism; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg01238044 chr22:24384105 GSTT1 -0.49 -4.57 -0.38 1.15e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7809950 0.678 rs4730235 chr7:107022506 T/C cg23024343 chr7:107201750 COG5 -0.46 -6.18 -0.49 8.6e-9 Coronary artery disease; TGCT cis rs9486719 0.741 rs2499799 chr6:96851676 T/C cg18709589 chr6:96969512 KIAA0776 0.73 5.0 0.41 1.88e-6 Migraine;Coronary artery disease; TGCT cis rs765787 0.530 rs1648289 chr15:45516494 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.37 -0.43 3.78e-7 Uric acid levels; TGCT cis rs10037670 1.000 rs10043393 chr5:153812047 G/C cg21964928 chr5:153872958 NA 0.26 5.03 0.41 1.71e-6 Behavioural disinhibition (generation interaction); TGCT cis rs9348721 0.673 rs9358934 chr6:26363755 G/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg25151919 chr3:44754333 ZNF502 -0.41 -4.77 -0.39 5.13e-6 Depressive symptoms; TGCT cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg20607798 chr8:58055168 NA -0.64 -5.39 -0.44 3.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7226408 0.948 rs11660471 chr18:34406836 C/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs514406 0.861 rs503015 chr1:53254456 T/C cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs9926296 0.607 rs11076629 chr16:89875259 T/C cg21285383 chr16:89894308 SPIRE2 0.33 4.45 0.37 1.92e-5 Vitiligo; TGCT cis rs7572733 0.515 rs13382697 chr2:198920560 A/C cg00792783 chr2:198669748 PLCL1 0.59 5.15 0.42 1.01e-6 Dermatomyositis; TGCT cis rs9311474 0.629 rs13081028 chr3:52555316 G/A cg10802521 chr3:52805072 NEK4 -0.64 -7.64 -0.57 4.98e-12 Electroencephalogram traits; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg19626725 chr5:178986131 RUFY1 -0.54 -7.34 -0.55 2.4e-11 Lung cancer; TGCT cis rs9894429 0.550 rs6565617 chr17:79612333 G/A cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs7829975 0.511 rs2980426 chr8:8145609 T/C cg08975724 chr8:8085496 FLJ10661 0.54 4.64 0.38 8.7e-6 Mood instability; TGCT cis rs2832191 0.632 rs2246777 chr21:30309586 T/C cg08807101 chr21:30365312 RNF160 -0.66 -6.25 -0.49 6.06e-9 Dental caries; TGCT cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg10117171 chr1:25599238 RHD -0.3 -4.92 -0.4 2.69e-6 Erythrocyte sedimentation rate; TGCT cis rs8031584 0.707 rs4556757 chr15:31188179 C/T cg08704250 chr15:31115839 NA -0.42 -6.28 -0.49 5.27e-9 Huntington's disease progression; TGCT cis rs11098499 0.863 rs1010740 chr4:120463409 C/T cg09307838 chr4:120376055 NA -0.69 -6.84 -0.52 3.24e-10 Corneal astigmatism; TGCT cis rs11785693 0.862 rs73183633 chr8:4994543 G/A cg26367366 chr8:4980734 NA 0.58 4.45 0.37 1.91e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs700651 0.821 rs771005 chr2:198675948 C/T cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial aneurysm; TGCT cis rs8180040 0.764 rs2132173 chr3:47247060 C/T cg27129171 chr3:47204927 SETD2 -0.72 -9.72 -0.66 6.21e-17 Colorectal cancer; TGCT cis rs12579753 0.917 rs10778834 chr12:82199742 A/C cg07988820 chr12:82153109 PPFIA2 -0.54 -5.55 -0.45 1.65e-7 Resting heart rate; TGCT trans rs208520 0.779 rs208451 chr6:66906155 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.93 -9.78 -0.66 4.3e-17 Exhaled nitric oxide output; TGCT cis rs6430585 0.536 rs3213892 chr2:136552517 G/A cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.88 -0.4 3.26e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg08219700 chr8:58056026 NA -0.39 -4.78 -0.39 4.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs72717009 0.778 rs9427400 chr1:161477204 C/T cg23840854 chr1:161414152 NA -0.98 -5.86 -0.47 3.95e-8 Rheumatoid arthritis; TGCT trans rs17684571 0.938 rs62412528 chr6:56558385 G/A cg14229071 chr15:89282588 NA 0.52 6.74 0.52 5.33e-10 Schizophrenia; TGCT cis rs1552244 0.626 rs2886396 chr3:10037670 C/T cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs10791097 0.568 rs4411284 chr11:130738568 A/C cg12179176 chr11:130786555 SNX19 0.84 10.16 0.67 5.21e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs433598 0.514 rs34894022 chr16:20678165 A/G cg08248577 chr16:19727447 IQCK;C16orf88 -0.25 -4.82 -0.4 4.07e-6 Schizophrenia; TGCT cis rs35160687 0.871 rs11127028 chr2:86537509 A/T cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.48e-7 Night sleep phenotypes; TGCT cis rs4664308 0.967 rs34248629 chr2:160902497 C/T cg03641300 chr2:160917029 PLA2R1 -0.27 -6.55 -0.51 1.39e-9 Idiopathic membranous nephropathy; TGCT cis rs6671200 1.000 rs12749053 chr1:95660556 A/G cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs854765 0.583 rs28428991 chr17:17827649 C/T cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg18876405 chr7:65276391 NA -0.37 -5.88 -0.47 3.63e-8 Calcium levels; TGCT cis rs12497850 1.000 rs4858831 chr3:48735558 C/T cg18654377 chr3:49208889 KLHDC8B -0.44 -6.1 -0.48 1.24e-8 Parkinson's disease; TGCT cis rs2688608 0.592 rs11000757 chr10:75486815 T/C cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs11585357 0.895 rs72646798 chr1:17614422 C/T cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg21016266 chr12:122356598 WDR66 0.52 7.24 0.54 4.23e-11 Mean corpuscular volume; TGCT cis rs12681287 0.752 rs9283958 chr8:87253048 T/C cg27223183 chr8:87520930 FAM82B -0.81 -5.66 -0.45 9.9e-8 Caudate activity during reward; TGCT cis rs2153535 0.542 rs915353 chr6:8440370 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.38e-7 Motion sickness; TGCT trans rs11722228 0.549 rs73212853 chr4:10096230 C/T cg26043149 chr18:55253948 FECH 1.15 10.93 0.7 6.83e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs8180040 0.676 rs13098228 chr3:47138253 A/G cg27129171 chr3:47204927 SETD2 0.75 9.48 0.65 2.35e-16 Colorectal cancer; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg26338869 chr17:61819248 STRADA -0.51 -4.73 -0.39 6.02e-6 Prudent dietary pattern; TGCT cis rs1577917 1.000 rs13196930 chr6:86652245 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.36 -0.43 3.86e-7 Response to antipsychotic treatment; TGCT cis rs10504229 0.906 rs56130194 chr8:58197061 C/A cg24829409 chr8:58192753 C8orf71 -0.58 -5.2 -0.42 7.88e-7 Developmental language disorder (linguistic errors); TGCT cis rs1008375 0.897 rs2315554 chr4:17660407 T/C cg16339924 chr4:17578868 LAP3 0.64 5.32 0.43 4.78e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs228437 0.507 rs228446 chr6:134901441 C/T cg09872934 chr6:134495829 SGK1 -0.51 -4.63 -0.38 9.17e-6 Melanoma; TGCT cis rs7769051 1.000 rs9399041 chr6:133096233 T/G cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs4478858 0.775 rs6701667 chr1:31707971 A/C cg00250761 chr1:31883323 NA -0.31 -5.98 -0.47 2.17e-8 Alcohol dependence; TGCT cis rs62380364 0.870 rs57055575 chr5:88150992 T/A cg22951263 chr5:87985283 NA -0.47 -4.55 -0.38 1.26e-5 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.615 rs56319216 chr4:152463716 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.74 -0.57 2.95e-12 Intelligence (multi-trait analysis); TGCT cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg25811766 chr13:21894605 NA 0.26 5.27 0.43 5.79e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs2228479 0.717 rs11649210 chr16:89807233 C/G cg27121462 chr16:89883253 FANCA 0.74 4.71 0.39 6.44e-6 Skin colour saturation; TGCT cis rs76419734 0.558 rs28536076 chr4:106527896 T/C cg24545054 chr4:106630052 GSTCD;INTS12 0.82 4.67 0.39 7.63e-6 Post bronchodilator FEV1; TGCT cis rs8177253 0.665 rs8177178 chr3:133463272 G/A cg08439880 chr3:133502540 NA -0.26 -4.73 -0.39 6.04e-6 Iron status biomarkers; TGCT cis rs941408 1.000 rs1076447 chr19:2792128 C/G cg06609049 chr19:2785107 THOP1 0.79 7.46 0.56 1.34e-11 Total cholesterol levels; TGCT cis rs9733 0.596 rs12403255 chr1:150660412 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.66 0.39 8.17e-6 Tonsillectomy; TGCT cis rs2742417 0.935 rs2673028 chr3:45759654 A/G cg04837898 chr3:45731254 SACM1L -0.51 -5.27 -0.43 5.85e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7666738 0.791 rs4699329 chr4:99056212 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs10927875 0.722 rs945425 chr1:16348412 T/C cg22431228 chr1:16359049 CLCNKA -0.25 -4.64 -0.38 8.84e-6 Dilated cardiomyopathy; TGCT cis rs597539 0.521 rs2060982 chr11:68612927 A/G cg21862992 chr11:68658383 NA 0.33 4.63 0.38 9.04e-6 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg05665937 chr4:1216051 CTBP1 0.25 4.75 0.39 5.64e-6 Obesity-related traits; TGCT cis rs2692947 0.832 rs2438978 chr2:96679740 G/C cg23100626 chr2:96804247 ASTL 0.38 4.45 0.37 1.9e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9894429 0.646 rs9904137 chr17:79613925 C/T cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs12134133 1.000 rs61822669 chr1:207421214 G/A cg02152968 chr1:207494213 CD55 0.64 5.06 0.41 1.47e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs769267 1.000 rs2285627 chr19:19467937 T/C cg19010396 chr19:19431384 KIAA0892;SF4 -0.57 -4.69 -0.39 6.96e-6 Tonsillectomy; TGCT cis rs1371867 0.846 rs959022 chr8:101295992 T/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs28595532 0.920 rs115841156 chr4:119740073 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs1692580 0.807 rs260508 chr1:2187085 T/G cg21194808 chr1:2205498 SKI 0.3 5.87 0.47 3.68e-8 Coronary artery disease; TGCT cis rs950027 0.620 rs1049518 chr15:45653367 G/A cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs4689592 0.503 rs2292461 chr4:7058473 C/T cg26116260 chr4:7069785 GRPEL1 0.69 5.17 0.42 9.12e-7 Monocyte percentage of white cells; TGCT cis rs11098499 0.955 rs6815725 chr4:120158410 C/A cg24670566 chr4:120433619 PDE5A 0.23 4.45 0.37 1.89e-5 Corneal astigmatism; TGCT cis rs624899 0.522 rs645584 chr19:11612466 A/G cg15237152 chr19:11649631 CNN1 0.44 5.66 0.45 1.01e-7 Presence of antiphospholipid antibodies; TGCT cis rs7937682 0.847 rs500163 chr11:111462649 T/G cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs3796352 1.000 rs2564926 chr3:53094730 G/A cg07884673 chr3:53033167 SFMBT1 -0.6 -6.13 -0.48 1.09e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2806561 0.765 rs641808 chr1:23514123 T/G cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs858239 0.699 rs858260 chr7:23212934 G/T cg05602783 chr7:23145260 KLHL7 -0.68 -5.52 -0.44 1.91e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6835098 0.962 rs10027704 chr4:174083107 T/C cg08422745 chr4:174089978 GALNT7 -0.93 -10.95 -0.7 6.1e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 -0.74 -5.34 -0.43 4.36e-7 Platelet count; TGCT cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg08859206 chr1:53392774 SCP2 -0.41 -6.06 -0.48 1.52e-8 Monocyte count; TGCT cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg07507251 chr3:52567010 NT5DC2 -0.45 -6.45 -0.5 2.28e-9 Bipolar disorder; TGCT cis rs9611565 0.512 rs5758464 chr22:42171300 A/G cg03806693 chr22:41940476 POLR3H 1.27 9.96 0.67 1.62e-17 Vitiligo; TGCT cis rs9674544 0.757 rs11871214 chr17:47124902 G/T cg20966754 chr17:47091339 IGF2BP1 -0.42 -4.6 -0.38 1.03e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs12477438 0.684 rs6756880 chr2:99676991 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs7542091 0.666 rs7537070 chr1:210043565 A/G cg22029157 chr1:209979665 IRF6 0.64 6.1 0.48 1.23e-8 Monobrow; TGCT cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9381040 0.610 rs2057002 chr6:41022962 G/T cg03526776 chr6:41159608 TREML2 0.26 4.95 0.41 2.38e-6 Alzheimer's disease (late onset); TGCT cis rs9894429 0.690 rs11869779 chr17:79570067 C/T cg18240062 chr17:79603768 NPLOC4 -0.84 -9.67 -0.66 8.03e-17 Eye color traits; TGCT cis rs797680 0.856 rs10874759 chr1:93630172 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.19 -0.42 8.19e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs12220898 0.749 rs74912367 chr10:50471012 T/A cg25968469 chr10:49687287 ARHGAP22 -0.28 -4.51 -0.38 1.51e-5 Inflammatory biomarkers; TGCT cis rs225245 0.817 rs1049379 chr17:33998802 G/C cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg07424592 chr7:64974309 NA 1.22 7.36 0.55 2.2e-11 Diabetic kidney disease; TGCT cis rs2692947 0.673 rs1168965 chr2:96787899 C/G cg22654517 chr2:96458247 NA -0.22 -4.88 -0.4 3.15e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7586673 0.930 rs2884364 chr2:161977647 G/A cg22496339 chr2:162101262 NA 0.53 4.81 0.4 4.27e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.680 rs34267968 chr4:99002574 A/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs909674 0.690 rs5750825 chr22:39831278 A/G cg02038168 chr22:39784481 NA -0.74 -5.67 -0.45 9.63e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9902453 0.868 rs9896012 chr17:28470091 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg10802521 chr3:52805072 NEK4 -0.7 -8.75 -0.62 1.28e-14 Bipolar disorder; TGCT cis rs6565180 0.926 rs12446288 chr16:30388709 A/G cg17640201 chr16:30407289 ZNF48 1.0 9.81 0.66 3.7e-17 Tonsillectomy; TGCT cis rs2439831 0.867 rs2447211 chr15:43936351 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.61 0.51 1.03e-9 Lung cancer in ever smokers; TGCT cis rs916888 0.773 rs199447 chr17:44812188 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.8 5.52 0.44 1.89e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1568079 0.516 rs2361382 chr10:125220299 C/G cg04278168 chr10:124578263 NA -0.42 -4.62 -0.38 9.35e-6 Body mass index; TGCT cis rs916888 0.773 rs199534 chr17:44824213 T/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.8 5.52 0.44 1.89e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs524023 0.958 rs11231825 chr11:64360274 T/C cg07733098 chr11:64478343 NRXN2 0.31 4.66 0.39 8.01e-6 Urate levels in obese individuals; TGCT cis rs11247915 0.583 rs34058882 chr1:26659794 C/T cg23732845 chr1:26663426 AIM1L -0.36 -4.55 -0.38 1.25e-5 Obesity-related traits; TGCT cis rs1865760 1.000 rs2071301 chr6:25914263 G/T cg17042849 chr6:26104293 HIST1H4C -0.51 -4.55 -0.38 1.24e-5 Height; TGCT cis rs4642101 0.737 rs9877165 chr3:12828497 C/T cg05775895 chr3:12838266 CAND2 0.78 8.7 0.62 1.73e-14 QRS complex (12-leadsum); TGCT cis rs12530845 1.000 rs78186690 chr7:135334991 G/C cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs999943 0.846 rs2274200 chr6:33625696 T/C cg14003231 chr6:33640908 ITPR3 0.4 4.86 0.4 3.48e-6 Obesity (extreme); TGCT cis rs6882076 0.883 rs1553318 chr5:156479323 G/C cg12943317 chr5:156479607 HAVCR1 -0.32 -5.51 -0.44 1.94e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs9916302 0.904 rs7216086 chr17:37709422 G/A cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs1008375 0.646 rs13146455 chr4:17565617 T/G cg10189774 chr4:17578691 LAP3 -0.65 -5.6 -0.45 1.32e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2302045 1.000 rs74000379 chr2:242034103 G/A cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg15691649 chr6:25882328 NA 0.49 5.98 0.47 2.17e-8 Blood metabolite levels; TGCT cis rs1903068 0.614 rs9998950 chr4:55996845 C/T cg16572876 chr4:56024045 NA 0.43 4.6 0.38 1.04e-5 Endometriosis; TGCT cis rs9362426 0.887 rs1209113 chr6:88079456 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.17 0.42 8.91e-7 Depressive episodes in bipolar disorder; TGCT cis rs10504229 1.000 rs72652905 chr8:58188355 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -5.39 -0.44 3.49e-7 Developmental language disorder (linguistic errors); TGCT cis rs11585357 0.671 rs2501776 chr1:17619279 C/T cg08277548 chr1:17600880 PADI3 0.85 8.9 0.62 5.75e-15 Hair shape; TGCT cis rs2299587 0.637 rs7832527 chr8:17889343 C/A cg01800426 chr8:17659068 MTUS1 -0.61 -5.17 -0.42 9.09e-7 Economic and political preferences; TGCT trans rs4650994 1.000 rs10913571 chr1:178526648 A/T cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.54e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs3812831 0.662 rs418027 chr13:114929344 A/C cg08824895 chr13:115047677 UPF3A 0.49 4.68 0.39 7.38e-6 Schizophrenia; TGCT cis rs208520 0.955 rs9345808 chr6:67008262 C/T cg07460842 chr6:66804631 NA 0.55 4.75 0.39 5.48e-6 Exhaled nitric oxide output; TGCT cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs13082711 0.911 rs13100751 chr3:27454964 A/G cg02860705 chr3:27208620 NA 0.35 4.83 0.4 3.9e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT trans rs2727020 0.729 rs2299650 chr11:49174007 A/C cg15704280 chr7:45808275 SEPT13 -0.69 -7.79 -0.57 2.36e-12 Coronary artery disease; TGCT cis rs7267979 1.000 rs2482941 chr20:25361216 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2692947 0.644 rs1168975 chr2:96814075 G/A cg23100626 chr2:96804247 ASTL 0.46 5.42 0.44 3.03e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs12142240 0.698 rs45517837 chr1:46859225 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs929596 1.000 rs929596 chr2:234674476 A/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.36 -5.58 -0.45 1.42e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs2153535 0.580 rs2327062 chr6:8453858 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs6671200 1.000 rs10747468 chr1:95686291 C/T cg03123541 chr1:95699097 RWDD3 0.84 6.26 0.49 5.66e-9 Stearic acid (18:0) levels; TGCT cis rs9309473 0.558 rs11679042 chr2:73907311 A/C cg07208825 chr2:73871855 ALMS1P 0.28 5.07 0.41 1.44e-6 Metabolite levels; TGCT cis rs459571 0.916 rs109536 chr9:136889987 G/C cg13789015 chr9:136890014 NCRNA00094 0.4 7.14 0.54 6.95e-11 Platelet distribution width; TGCT cis rs3892630 1.000 rs3892630 chr19:33181484 A/G cg22980127 chr19:33182716 NUDT19 -0.72 -5.11 -0.42 1.16e-6 Red blood cell traits; TGCT cis rs7666738 0.715 rs116787789 chr4:98718720 G/A cg05340658 chr4:99064831 C4orf37 0.47 5.49 0.44 2.21e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg23758822 chr17:41437982 NA 0.69 6.41 0.5 2.75e-9 Menopause (age at onset); TGCT cis rs11098499 0.820 rs28394116 chr4:120524283 T/G cg09307838 chr4:120376055 NA 0.67 6.35 0.5 3.65e-9 Corneal astigmatism; TGCT cis rs1129187 0.702 rs2296805 chr6:42928758 T/G cg10862848 chr6:42927986 GNMT -0.39 -4.67 -0.39 7.61e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs11203032 0.831 rs12217507 chr10:90922828 G/A cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs2982552 0.873 rs2152750 chr6:152070145 C/T cg22157087 chr6:152012887 ESR1 -0.21 -5.27 -0.43 5.79e-7 Bone properties (heel); TGCT cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg21644426 chr2:191273491 MFSD6 0.66 6.24 0.49 6.46e-9 Pulse pressure; TGCT cis rs11190604 1.000 rs10883510 chr10:102297018 C/T cg23241863 chr10:102295624 HIF1AN 0.67 4.8 0.4 4.46e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12497850 0.797 rs61583136 chr3:49189195 C/T cg18654377 chr3:49208889 KLHDC8B -0.38 -4.79 -0.4 4.61e-6 Parkinson's disease; TGCT cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Vitiligo; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg08736216 chr1:53307985 ZYG11A -0.25 -4.68 -0.39 7.47e-6 Monocyte count; TGCT cis rs910316 0.763 rs175036 chr14:75464295 C/T cg08847533 chr14:75593920 NEK9 -0.84 -9.15 -0.64 1.4e-15 Height; TGCT cis rs3784262 0.679 rs11071365 chr15:58334126 G/A cg12031962 chr15:58353849 ALDH1A2 -0.55 -8.46 -0.6 6.31e-14 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9467711 0.790 rs1979 chr6:26377591 G/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.28 0.43 5.65e-7 Prudent dietary pattern; TGCT cis rs7224685 0.774 rs8081417 chr17:3902650 T/A cg25235380 chr17:4167449 ANKFY1 -0.54 -4.57 -0.38 1.17e-5 Type 2 diabetes; TGCT cis rs2274459 0.545 rs35329444 chr6:33588985 C/A cg11783815 chr6:33558433 C6orf227 0.32 4.56 0.38 1.21e-5 Obesity (extreme); TGCT cis rs12142240 0.698 rs1053628 chr1:46827769 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs4383453 0.539 rs2877709 chr3:123100304 A/G cg04890266 chr3:123102914 ADCY5 0.5 8.34 0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs73198271 0.595 rs56152067 chr8:8592992 G/A ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2455799 0.559 rs9813577 chr3:15909323 C/T cg13420985 chr3:16524424 RFTN1 0.35 4.6 0.38 1.05e-5 Mean platelet volume; TGCT cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg15691649 chr6:25882328 NA 0.43 5.34 0.43 4.27e-7 Blood metabolite levels; TGCT cis rs8177253 1.000 rs8177262 chr3:133480652 A/G cg08439880 chr3:133502540 NA 0.29 5.37 0.43 3.79e-7 Iron status biomarkers; TGCT cis rs12620999 0.941 rs4408676 chr2:238085280 C/T cg23555395 chr2:238036564 NA -0.29 -4.99 -0.41 1.95e-6 Systemic lupus erythematosus; TGCT cis rs7772486 0.846 rs2144478 chr6:146381445 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.86 0.4 3.48e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs617219 0.551 rs2131978 chr5:78613986 G/A cg23987322 chr5:78407566 BHMT -0.35 -4.73 -0.39 5.99e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs9549367 0.713 rs1755690 chr13:113824266 T/C cg00898013 chr13:113819073 PROZ 0.55 7.02 0.53 1.27e-10 Platelet distribution width; TGCT cis rs288326 0.561 rs77024950 chr2:183797227 T/C cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs1568889 1.000 rs11826837 chr11:28322566 C/G cg06544937 chr11:28130018 METT5D1;KIF18A -0.8 -8.39 -0.6 9.19e-14 Bipolar disorder; TGCT trans rs1814175 0.740 rs10839439 chr11:49918240 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs1483890 1.000 rs1483890 chr3:69410725 A/G cg22125112 chr3:69402811 FRMD4B 0.27 4.52 0.38 1.45e-5 Resting heart rate; TGCT cis rs11785400 0.793 rs2976400 chr8:143743611 G/A cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs2439831 0.571 rs2470121 chr15:43937618 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.73 4.95 0.41 2.38e-6 Lung cancer in ever smokers; TGCT cis rs7267979 0.773 rs6132821 chr20:25226192 A/G cg03522245 chr20:25566470 NINL 0.57 5.67 0.45 9.54e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs68170813 0.559 rs6971675 chr7:106833797 G/A cg02696742 chr7:106810147 HBP1 -0.7 -5.81 -0.46 4.91e-8 Coronary artery disease; TGCT cis rs8177253 1.000 rs8177271 chr3:133482230 G/A cg16414030 chr3:133502952 NA -0.61 -9.47 -0.65 2.44e-16 Iron status biomarkers; TGCT cis rs7666738 0.830 rs10050008 chr4:99025313 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs35883536 0.551 rs6666607 chr1:101032368 A/G cg10298815 chr1:101004474 GPR88 -0.25 -4.61 -0.38 9.74e-6 Monocyte count; TGCT cis rs4654899 0.733 rs6698440 chr1:21258712 C/T cg01072550 chr1:21505969 NA -0.53 -8.69 -0.62 1.83e-14 Superior frontal gyrus grey matter volume; TGCT cis rs453301 0.624 rs2979256 chr8:8871710 C/T cg06636001 chr8:8085503 FLJ10661 0.77 6.54 0.51 1.43e-9 Joint mobility (Beighton score); TGCT cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.41 7.14 0.54 6.78e-11 Schizophrenia; TGCT cis rs507506 0.712 rs1875673 chr17:7108506 T/G cg25256661 chr17:7137939 DVL2 -0.57 -5.16 -0.42 9.6e-7 Adiponectin levels; TGCT trans rs916888 0.610 rs199446 chr17:44813169 G/A cg01341218 chr17:43662625 NA -0.83 -7.37 -0.55 2.14e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs992157 0.710 rs13026485 chr2:219057984 C/T cg00012203 chr2:219082015 ARPC2 -0.82 -10.54 -0.69 6.02e-19 Colorectal cancer; TGCT cis rs7428 0.527 rs3184780 chr2:85549547 C/T cg24342717 chr2:85555507 TGOLN2 -0.48 -8.29 -0.6 1.6e-13 Ear protrusion; TGCT cis rs116095464 0.614 rs62344292 chr5:244630 G/A cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs9467773 1.000 rs1884948 chr6:26567988 G/A cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs55985953 chr4:119764971 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs617219 0.710 rs2166344 chr5:78534134 T/G cg23514016 chr5:78407564 BHMT 0.32 4.87 0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2439831 1.000 rs2601014 chr15:43756013 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.77 4.61 0.38 9.74e-6 Lung cancer in ever smokers; TGCT cis rs9911578 0.967 rs7502208 chr17:57165097 G/A cg05425664 chr17:57184151 TRIM37 -0.68 -6.84 -0.52 3.19e-10 Intelligence (multi-trait analysis); TGCT cis rs9790314 0.586 rs16832246 chr3:161109916 A/G cg03342759 chr3:160939853 NMD3 0.53 5.53 0.45 1.77e-7 Morning vs. evening chronotype; TGCT cis rs9443189 0.615 rs602873 chr6:76323818 T/A cg01950844 chr6:76311363 SENP6 0.99 6.27 0.49 5.49e-9 Prostate cancer; TGCT cis rs11098499 0.779 rs7699346 chr4:120310542 C/T cg09307838 chr4:120376055 NA 0.62 5.94 0.47 2.66e-8 Corneal astigmatism; TGCT cis rs17001868 0.892 rs12483888 chr22:40801312 A/G cg07138101 chr22:40742427 ADSL 0.71 4.72 0.39 6.31e-6 Mammographic density (dense area); TGCT cis rs73198271 0.737 rs565203 chr8:8632957 T/C cg06671706 chr8:8559999 CLDN23 -0.37 -4.84 -0.4 3.81e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg09904177 chr6:26538194 HMGN4 0.63 6.21 0.49 7.48e-9 Intelligence (multi-trait analysis); TGCT cis rs7264396 0.635 rs6058365 chr20:34508092 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs1215050 0.744 rs966380 chr4:98435389 C/T cg05340658 chr4:99064831 C4orf37 0.4 4.55 0.38 1.26e-5 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg11494091 chr17:61959527 GH2 0.42 7.27 0.55 3.61e-11 Height; TGCT cis rs28595532 0.920 rs115688334 chr4:119770805 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs10504229 1.000 rs66479724 chr8:58188309 T/G cg24829409 chr8:58192753 C8orf71 -0.57 -5.35 -0.43 4.03e-7 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.626 rs4855846 chr3:49683526 G/A cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs6570726 0.738 rs6917199 chr6:145918320 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs981844 0.740 rs10009844 chr4:154681576 C/T cg14289246 chr4:154710475 SFRP2 -0.88 -7.71 -0.57 3.47e-12 Response to statins (LDL cholesterol change); TGCT cis rs10782582 0.545 rs12138018 chr1:76186794 T/C cg22875332 chr1:76189707 ACADM -0.53 -5.78 -0.46 5.81e-8 Daytime sleep phenotypes; TGCT cis rs5417 0.775 rs222852 chr17:7140606 A/G cg25256661 chr17:7137939 DVL2 0.56 5.45 0.44 2.61e-7 Diastolic blood pressure; TGCT cis rs1497406 0.591 rs12024558 chr1:16518748 T/A cg20430773 chr1:16534157 ARHGEF19 0.47 5.33 0.43 4.44e-7 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9916302 0.706 rs8078599 chr17:37518660 C/T cg03321784 chr17:37729644 NA -0.49 -4.98 -0.41 2.04e-6 Glomerular filtration rate (creatinine); TGCT cis rs9952991 0.941 rs888270 chr18:12774894 G/A cg24737193 chr18:12778029 NA -0.55 -5.89 -0.47 3.32e-8 Inflammatory skin disease; TGCT cis rs2282802 0.685 rs6580473 chr5:139646962 C/T cg01081189 chr5:139537190 NA -0.28 -4.9 -0.4 2.91e-6 Intelligence (multi-trait analysis); TGCT cis rs950027 0.620 rs2453533 chr15:45641225 C/A cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs2486012 1.000 rs3011226 chr1:44324060 G/A cg12908607 chr1:44402522 ARTN -0.72 -5.68 -0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT trans rs9951602 0.512 rs8098115 chr18:76653986 G/T cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs4919694 1.000 rs11191490 chr10:104745174 T/A cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT cis rs4722404 0.835 rs28458463 chr7:3139506 G/A cg17467898 chr7:2289054 NUDT1 -0.17 -4.46 -0.37 1.81e-5 Atopic dermatitis; TGCT cis rs2842992 0.724 rs4709368 chr6:160204127 C/T cg11366901 chr6:160182831 ACAT2 -0.78 -5.8 -0.46 5.25e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs11190604 1.000 rs6584383 chr10:102303065 C/G cg16342193 chr10:102329863 NA -0.41 -4.93 -0.4 2.57e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs763121 0.853 rs3747170 chr22:39067331 G/A cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs2404602 0.692 rs35195096 chr15:76938447 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs478304 0.903 rs546202 chr11:65510024 C/T cg17480646 chr11:65405466 SIPA1 -0.43 -5.42 -0.44 2.98e-7 Acne (severe); TGCT cis rs4268898 0.760 rs55863105 chr2:24570695 C/T cg02683114 chr2:24398427 C2orf84 0.2 4.92 0.4 2.65e-6 Asthma; TGCT cis rs240110 0.539 rs6934256 chr6:101338728 G/A cg09795085 chr6:101329169 ASCC3 0.56 4.45 0.37 1.85e-5 Neuroticism; TGCT cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs7647973 1.000 rs7644148 chr3:49545241 G/A cg07636037 chr3:49044803 WDR6 -0.7 -5.73 -0.46 7.08e-8 Menarche (age at onset); TGCT cis rs7582180 0.629 rs6736576 chr2:100950854 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.95 -0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT cis rs67311347 0.955 rs6782746 chr3:40510592 A/G cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs2841277 0.708 rs28454709 chr14:105405942 G/A cg21017887 chr14:105400489 NA 0.37 5.19 0.42 8.23e-7 Rheumatoid arthritis; TGCT cis rs4332037 0.539 rs4719416 chr7:2106608 G/A cg25834613 chr7:1915315 MAD1L1 -0.45 -4.92 -0.4 2.7e-6 Bipolar disorder; TGCT cis rs7208859 0.573 rs55661352 chr17:29045628 A/G cg14008862 chr17:28927542 LRRC37B2 0.78 4.68 0.39 7.38e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10791097 0.694 rs2155751 chr11:130755240 G/A cg14779329 chr11:130786720 SNX19 0.29 5.01 0.41 1.85e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1008375 1.000 rs10012335 chr4:17628630 C/G cg16339924 chr4:17578868 LAP3 0.62 5.11 0.42 1.17e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs208520 0.690 rs207096 chr6:66797287 T/C cg07460842 chr6:66804631 NA -0.94 -9.91 -0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs17767294 0.612 rs9461424 chr6:27919401 G/A cg08851530 chr6:28072375 NA 0.78 4.81 0.4 4.34e-6 Parkinson's disease; TGCT cis rs6087990 0.806 rs875041 chr20:31383530 C/T cg13636640 chr20:31349939 DNMT3B 1.1 15.53 0.81 7.14e-31 Ulcerative colitis; TGCT cis rs9291683 0.527 rs3822247 chr4:10094671 G/A cg00071950 chr4:10020882 SLC2A9 -0.54 -5.63 -0.45 1.16e-7 Bone mineral density; TGCT cis rs10875746 0.669 rs9634261 chr12:48686871 A/G cg20731937 chr12:48336164 NA 0.61 4.59 0.38 1.07e-5 Longevity (90 years and older); TGCT cis rs11718455 0.960 rs35666538 chr3:44004826 A/G cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg08048268 chr3:133502702 NA -0.54 -7.23 -0.54 4.34e-11 Iron status biomarkers; TGCT cis rs2014572 0.933 rs8107516 chr19:57758445 A/G cg24459738 chr19:57751996 ZNF805 -0.56 -5.6 -0.45 1.29e-7 Hyperactive-impulsive symptoms; TGCT cis rs514406 0.861 rs503015 chr1:53254456 T/C cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs595982 0.546 rs10401443 chr19:49402059 C/A cg11637076 chr19:49575188 KCNA7 -0.43 -5.31 -0.43 4.85e-7 Red cell distribution width; TGCT cis rs11971779 1.000 rs11971779 chr7:139040258 A/G cg07862535 chr7:139043722 LUC7L2 -0.81 -6.02 -0.48 1.83e-8 Diisocyanate-induced asthma; TGCT cis rs4819052 0.851 rs7279011 chr21:46655995 G/A cg06618935 chr21:46677482 NA -0.36 -5.48 -0.44 2.23e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13242816 1.000 rs35364754 chr7:116109716 T/G cg02799643 chr7:116139180 CAV2 -0.48 -5.45 -0.44 2.56e-7 P wave duration; TGCT cis rs6430585 0.527 rs57530667 chr2:136444338 A/G cg07169764 chr2:136633963 MCM6 1.0 9.14 0.63 1.51e-15 Corneal structure; TGCT cis rs1215050 0.791 rs260902 chr4:98764694 G/A cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3096299 0.933 rs3096297 chr16:89453155 T/G cg02187348 chr16:89574699 SPG7 0.48 4.71 0.39 6.63e-6 Multiple myeloma (IgH translocation); TGCT cis rs72945132 0.882 rs7943547 chr11:70133282 C/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9915657 0.870 rs759499 chr17:70133177 C/T cg06234051 chr17:70120541 SOX9 -0.23 -4.64 -0.38 8.76e-6 Thyroid hormone levels; TGCT cis rs12477438 0.798 rs10202452 chr2:99569409 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.7 -6.19 -0.49 8.1e-9 Chronic sinus infection; TGCT cis rs7666738 0.830 rs28515641 chr4:98726419 G/A cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg25151919 chr3:44754333 ZNF502 -0.39 -4.54 -0.38 1.3e-5 Depressive symptoms; TGCT cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg06896619 chr17:61851486 DDX42;CCDC47 0.51 5.18 0.42 8.6e-7 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs9999200 chr4:99030690 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4851266 0.966 rs1465800 chr2:100834777 T/C cg07810366 chr2:100720526 AFF3 -0.39 -5.73 -0.46 7.19e-8 Educational attainment; TGCT cis rs950169 0.800 rs4099846 chr15:84956894 C/G cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs78456975 0.739 rs11891867 chr2:1517894 C/T cg01028140 chr2:1542097 TPO -0.36 -4.76 -0.39 5.3e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs79349575 0.783 rs2112617 chr17:46977125 G/A cg07967210 chr17:47022446 SNF8 0.44 6.2 0.49 7.58e-9 Type 2 diabetes; TGCT cis rs2549003 1.000 rs9282763 chr5:131822133 T/C cg00255919 chr5:131827918 IRF1 0.2 4.65 0.39 8.22e-6 Asthma (sex interaction); TGCT cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs9883204 0.951 rs7613951 chr3:123070517 C/T cg04890266 chr3:123102914 ADCY5 0.37 5.0 0.41 1.92e-6 Birth weight; TGCT cis rs7809950 1.000 rs3801954 chr7:107117048 C/T cg23024343 chr7:107201750 COG5 -0.34 -5.35 -0.43 4.11e-7 Coronary artery disease; TGCT cis rs13217239 0.646 rs12527111 chr6:27006475 C/T cg05738196 chr6:26577821 NA 0.49 4.75 0.39 5.45e-6 Schizophrenia; TGCT cis rs2535633 0.661 rs4515041 chr3:52996032 T/A cg05573699 chr3:52720067 GNL3;PBRM1 0.56 5.29 0.43 5.37e-7 Body mass index; TGCT cis rs7246657 0.714 rs12972195 chr19:37752505 T/C cg03233940 chr19:37894644 NA -0.39 -4.93 -0.4 2.56e-6 Coronary artery calcification; TGCT trans rs804280 0.509 rs10109241 chr8:11784985 A/T cg15556689 chr8:8085844 FLJ10661 0.77 7.16 0.54 6.11e-11 Myopia (pathological); TGCT cis rs709400 0.663 rs10141388 chr14:103939679 A/G cg12935359 chr14:103987150 CKB -0.36 -5.56 -0.45 1.59e-7 Body mass index; TGCT cis rs12368653 0.666 rs799265 chr12:58112189 A/G cg12615879 chr12:58013172 SLC26A10 0.47 5.67 0.45 9.53e-8 Multiple sclerosis; TGCT cis rs10504229 0.593 rs16921626 chr8:58040359 C/T cg21724239 chr8:58056113 NA 0.34 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs2856321 1.000 rs11054424 chr12:11860170 C/G cg11375112 chr12:11883006 ETV6 0.3 4.48 0.37 1.67e-5 Height; TGCT cis rs616402 0.564 rs7419116 chr1:10578606 G/A cg17425144 chr1:10567563 PEX14 0.54 7.98 0.58 8.27e-13 Breast size; TGCT cis rs6032067 0.636 rs6032095 chr20:43913255 A/T cg16667508 chr20:43936853 MATN4;RBPJL 0.42 7.1 0.54 8.47e-11 Blood protein levels; TGCT cis rs7586879 0.681 rs6752483 chr2:25120086 C/T cg15423357 chr2:25149977 NA 0.48 4.62 0.38 9.27e-6 Body mass index; TGCT cis rs9486719 0.895 rs3798294 chr6:97049587 G/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs9796 0.621 rs2928142 chr15:41470449 T/C cg18705301 chr15:41695430 NDUFAF1 0.52 7.17 0.54 5.94e-11 Menopause (age at onset); TGCT trans rs7615952 0.551 rs12695470 chr3:125635718 C/A cg07211511 chr3:129823064 LOC729375 -0.45 -6.72 -0.52 5.83e-10 Blood pressure (smoking interaction); TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg18538332 chr22:24372958 LOC391322 -1.01 -12.83 -0.76 1.7e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467711 1.000 rs6923139 chr6:26313348 C/T cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg00814883 chr7:100076585 TSC22D4 -0.82 -8.37 -0.6 1.03e-13 Platelet count; TGCT cis rs1971762 0.545 rs10783585 chr12:53977317 T/G cg16917193 chr12:54089295 NA 0.93 9.72 0.66 5.91e-17 Height; TGCT trans rs7613875 0.620 rs11721204 chr3:49982765 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.29 0.6 1.6e-13 Body mass index; TGCT cis rs7666738 0.830 rs10017201 chr4:98983561 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7226408 0.901 rs11081991 chr18:34743948 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs634534 0.622 rs531612 chr11:65705432 C/T cg02427764 chr11:65769310 BANF1;EIF1AD -0.56 -5.51 -0.44 1.95e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs6074578 0.535 rs6086289 chr20:138615 G/A cg16931068 chr20:139680 DEFB127 0.27 4.47 0.37 1.75e-5 Hirschsprung disease; TGCT cis rs362272 0.545 rs2239725 chr4:3305739 C/T cg06533319 chr4:3265114 C4orf44 -0.28 -5.39 -0.44 3.35e-7 Serum sulfate level; TGCT cis rs7829975 0.688 rs7837587 chr8:8378992 T/C cg15556689 chr8:8085844 FLJ10661 0.67 6.2 0.49 7.84e-9 Mood instability; TGCT cis rs453301 0.571 rs2929456 chr8:9083416 G/A cg06636001 chr8:8085503 FLJ10661 -0.56 -4.97 -0.41 2.14e-6 Joint mobility (Beighton score); TGCT cis rs924607 1.000 rs12523022 chr5:598643 C/T cg18765565 chr5:669397 TPPP -0.58 -6.32 -0.49 4.25e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs6088580 0.634 rs6120642 chr20:33012531 A/G cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs2777491 0.874 rs11633799 chr15:41576538 G/A cg18705301 chr15:41695430 NDUFAF1 -0.72 -9.31 -0.64 5.77e-16 Ulcerative colitis; TGCT cis rs6089829 0.962 rs6011544 chr20:61658782 T/C cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs765787 0.530 rs11855435 chr15:45522117 G/A cg24006582 chr15:45444508 DUOX1 -0.26 -5.64 -0.45 1.12e-7 Uric acid levels; TGCT cis rs16865717 0.513 rs6431838 chr2:7036838 G/C cg20486407 chr2:7037101 RSAD2 -0.41 -5.42 -0.44 2.95e-7 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs62380364 0.602 rs11743441 chr5:88065637 G/T cg24804195 chr5:87968844 LOC645323 -0.57 -5.45 -0.44 2.6e-7 Intelligence (multi-trait analysis); TGCT cis rs1729951 0.546 rs12054219 chr3:136677472 G/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs2439831 1.000 rs2601014 chr15:43756013 G/C cg02155558 chr15:43621948 ADAL;LCMT2 1.0 6.7 0.52 6.45e-10 Lung cancer in ever smokers; TGCT cis rs9788682 0.748 rs637137 chr15:78873976 T/A cg24631222 chr15:78858424 CHRNA5 0.86 6.45 0.5 2.3e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2204008 0.805 rs11179579 chr12:38213957 A/C cg13010199 chr12:38710504 ALG10B 0.6 4.68 0.39 7.47e-6 Bladder cancer; TGCT cis rs13256369 1.000 rs1109619 chr8:8571616 G/T cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs447921 1.000 rs447921 chr17:74414559 T/C cg09812376 chr17:74270190 QRICH2 0.44 4.5 0.37 1.57e-5 Mitochondrial DNA levels; TGCT cis rs2820315 0.867 rs2644121 chr1:201881284 A/G cg12730843 chr1:201915899 LMOD1 -0.26 -4.9 -0.4 2.91e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs67072384 1.000 rs72964198 chr11:72446464 C/T cg03713592 chr11:72463424 ARAP1 -0.94 -4.8 -0.4 4.41e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs4889855 0.530 rs78012645 chr17:78550939 C/T cg16591659 chr17:78472290 NA 0.28 4.45 0.37 1.89e-5 Fractional excretion of uric acid; TGCT cis rs6087771 0.747 rs6058261 chr20:30235470 C/A cg13852791 chr20:30311386 BCL2L1 0.8 7.08 0.54 9.22e-11 Subcortical brain region volumes;Putamen volume; TGCT cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs2172802 0.570 rs10020698 chr4:62516024 T/C cg04118610 chr4:62707027 LPHN3 0.41 4.89 0.4 3.07e-6 Partial epilepsies; TGCT cis rs9297145 0.761 rs28545226 chr7:98732472 A/T cg05967295 chr7:98741636 SMURF1 1.01 12.7 0.75 3.38e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs17102423 0.623 rs4902368 chr14:65612048 A/G cg11161011 chr14:65562177 MAX 0.4 5.51 0.44 1.98e-7 Obesity-related traits; TGCT cis rs10883723 0.810 rs2296585 chr10:104245549 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg26116260 chr4:7069785 GRPEL1 1.13 11.1 0.71 2.59e-20 Monocyte percentage of white cells; TGCT cis rs3008870 0.755 rs2815365 chr1:67499628 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.48 0.61 5.61e-14 Lymphocyte percentage of white cells; TGCT cis rs1865760 0.566 rs9295686 chr6:26081983 G/C cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs698813 0.572 rs13424464 chr2:44482263 A/C cg00619915 chr2:44497795 NA -0.24 -5.68 -0.45 9.26e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs12579753 0.917 rs7138651 chr12:82253615 A/G cg07988820 chr12:82153109 PPFIA2 0.53 5.64 0.45 1.07e-7 Resting heart rate; TGCT trans rs1496653 0.602 rs36124326 chr3:23435327 T/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs7659604 0.702 rs58649165 chr4:122693752 C/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.32 -5.2 -0.42 7.91e-7 Type 2 diabetes; TGCT cis rs9733 0.596 rs2867301 chr1:150653795 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs11249608 0.548 rs6875473 chr5:178451387 C/A cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs36051895 0.659 rs12336577 chr9:5063690 T/A cg02405213 chr9:5042618 JAK2 -0.71 -9.22 -0.64 9.86e-16 Pediatric autoimmune diseases; TGCT cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs6840360 0.582 rs4696260 chr4:152318924 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.67e-9 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.547 rs12365680 chr11:130749059 C/T cg14779329 chr11:130786720 SNX19 0.29 5.08 0.42 1.33e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3780378 0.967 rs1328917 chr9:5049065 G/T cg02405213 chr9:5042618 JAK2 -0.58 -7.5 -0.56 1.09e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9527 0.830 rs12249194 chr10:104643698 T/C cg04362960 chr10:104952993 NT5C2 0.62 5.06 0.41 1.46e-6 Arsenic metabolism; TGCT cis rs950027 0.787 rs2433616 chr15:45728599 A/G cg26924012 chr15:45694286 SPATA5L1 0.67 7.17 0.54 5.91e-11 Response to fenofibrate (adiponectin levels); TGCT cis rs13191362 1.000 rs13207239 chr6:163008772 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11190604 1.000 rs2495760 chr10:102318771 T/C cg23241863 chr10:102295624 HIF1AN 0.67 4.9 0.4 2.92e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28374715 0.532 rs11854632 chr15:41682094 A/G cg18705301 chr15:41695430 NDUFAF1 0.9 15.29 0.81 2.65e-30 Ulcerative colitis; TGCT cis rs7625328 0.679 rs2049149 chr3:132776901 A/G cg18115215 chr3:132757090 TMEM108 0.41 4.58 0.38 1.1e-5 Itch intensity from mosquito bite; TGCT cis rs1153858 1.000 rs1049503 chr15:45653707 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT trans rs57221529 0.825 rs72703051 chr5:582997 G/A cg25482853 chr8:67687455 SGK3 1.22 9.53 0.65 1.7e-16 Lung disease severity in cystic fibrosis; TGCT cis rs7681423 1.000 rs7659024 chr4:155520930 G/A cg20735720 chr4:155535218 FGG -0.46 -6.8 -0.52 4e-10 Fibrinogen; TGCT cis rs7020830 0.505 rs12553878 chr9:37095705 C/T cg14294708 chr9:37120828 ZCCHC7 0.8 8.65 0.61 2.19e-14 Schizophrenia; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg25703541 chr22:24373054 LOC391322 -0.61 -5.86 -0.47 3.88e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2288278 0.601 rs4793564 chr17:46599404 C/G cg25032089 chr17:46643351 HOXB3 -0.42 -5.01 -0.41 1.86e-6 Hand grip strength; TGCT cis rs727563 0.555 rs5751136 chr22:42075581 T/A cg17554472 chr22:41940697 POLR3H 0.49 5.09 0.42 1.31e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs875971 1.000 rs778699 chr7:65868290 G/A cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg11003573 chr3:44754125 ZNF502 -0.45 -5.13 -0.42 1.1e-6 Depressive symptoms; TGCT cis rs35306767 0.715 rs17221463 chr10:1038040 T/C cg26597838 chr10:835615 NA 0.63 6.97 0.53 1.62e-10 Eosinophil percentage of granulocytes; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs4851266 1.000 rs4851267 chr2:100824104 G/A cg07810366 chr2:100720526 AFF3 -0.41 -5.82 -0.46 4.72e-8 Educational attainment; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg09060608 chr5:178986726 RUFY1 0.61 7.14 0.54 6.87e-11 Lung cancer; TGCT cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg15687855 chr3:44754131 ZNF502 -0.43 -5.25 -0.43 6.25e-7 Depressive symptoms; TGCT cis rs425277 0.958 rs626479 chr1:2110260 A/G cg03732007 chr1:2071316 PRKCZ -0.24 -5.15 -0.42 9.75e-7 Height; TGCT cis rs904251 0.523 rs9369005 chr6:37483109 A/G cg25019722 chr6:37503610 NA -0.51 -7.81 -0.57 2.06e-12 Cognitive performance; TGCT cis rs1857353 1.000 rs58890548 chr1:75887154 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs2455799 0.613 rs11128760 chr3:15873407 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.76e-6 Mean platelet volume; TGCT cis rs9807989 0.507 rs7581119 chr2:103049865 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs12497850 0.931 rs4974087 chr3:48919232 A/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs2688608 0.620 rs12253408 chr10:75495956 G/T cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT trans rs34421088 0.560 rs2618434 chr8:11398865 A/G cg15556689 chr8:8085844 FLJ10661 -0.75 -7.08 -0.54 9.46e-11 Neuroticism; TGCT cis rs4595586 0.545 rs2388176 chr12:39372357 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs6988636 1.000 rs11988157 chr8:124194740 A/G cg23067535 chr8:124195133 FAM83A 0.35 5.45 0.44 2.6e-7 Urinary uromodulin levels; TGCT cis rs319204 0.918 rs2963080 chr5:146261089 C/T cg25021259 chr5:146258546 PPP2R2B 0.38 4.66 0.39 7.94e-6 Schizophrenia; TGCT cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.580 rs1932282 chr6:8477330 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9467773 1.000 rs6930120 chr6:26555484 A/G cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.559 rs12536485 chr7:106978005 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs68170813 0.559 rs6947675 chr7:106817184 T/C cg02696742 chr7:106810147 HBP1 -0.72 -6.28 -0.49 5.29e-9 Coronary artery disease; TGCT cis rs422249 0.504 rs174538 chr11:61560081 G/A cg01500311 chr11:61656094 FADS3 -0.32 -5.24 -0.43 6.64e-7 Trans fatty acid levels; TGCT cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg26116260 chr4:7069785 GRPEL1 1.08 10.43 0.68 1.12e-18 Monocyte percentage of white cells; TGCT cis rs10504229 1.000 rs59843034 chr8:58195756 T/G cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs861020 0.630 rs685248 chr1:210008367 C/G cg05527609 chr1:210001259 C1orf107 0.85 7.37 0.55 2.05e-11 Orofacial clefts; TGCT cis rs9911578 0.935 rs304261 chr17:56813782 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs317865 0.737 rs73234668 chr4:16240306 T/C cg04764131 chr4:16228633 TAPT1;FLJ39653 0.74 4.48 0.37 1.68e-5 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs7528419 0.591 rs4970837 chr1:109822008 G/T cg00908766 chr1:109817496 CELSR2 0.45 4.59 0.38 1.06e-5 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs35883536 0.548 rs3176860 chr1:101187219 A/G cg06223162 chr1:101003688 GPR88 0.34 5.49 0.44 2.2e-7 Monocyte count; TGCT cis rs10823500 0.777 rs10762348 chr10:71952322 C/A cg04118878 chr10:71993077 PPA1 0.59 5.41 0.44 3.15e-7 Blood protein levels; TGCT cis rs10465746 0.967 rs1475263 chr1:84339497 A/T cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs6460942 1.000 rs17274870 chr7:12406221 G/T cg06484146 chr7:12443880 VWDE -0.57 -5.34 -0.43 4.36e-7 Coronary artery disease; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg22166914 chr1:53195759 ZYG11B 0.39 6.32 0.49 4.39e-9 Monocyte count; TGCT cis rs12541335 0.639 rs11779277 chr8:22200683 C/T cg09517075 chr8:22133004 PIWIL2 0.25 4.97 0.41 2.21e-6 Hypertriglyceridemia; TGCT cis rs57590327 0.555 rs13062054 chr3:81833906 A/G cg07356753 chr3:81810745 GBE1 -0.73 -6.73 -0.52 5.57e-10 Extraversion; TGCT trans rs1814175 0.781 rs1851872 chr11:50009770 A/G cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg09436375 chr6:42928200 GNMT -0.42 -5.41 -0.44 3.16e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7010267 0.902 rs4242592 chr8:119968975 T/G cg17171407 chr8:119960777 TNFRSF11B 0.33 6.26 0.49 5.67e-9 Total body bone mineral density (age 45-60); TGCT cis rs76419734 0.718 rs11730660 chr4:106800379 A/C cg24545054 chr4:106630052 GSTCD;INTS12 1.01 4.61 0.38 9.71e-6 Post bronchodilator FEV1; TGCT cis rs3733585 0.699 rs6834893 chr4:9959123 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1218582 0.628 rs12130132 chr1:154880386 C/T cg09359103 chr1:154839909 KCNN3 -0.63 -12.14 -0.74 7.75e-23 Prostate cancer; TGCT cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg18252515 chr7:66147081 NA -1.09 -7.16 -0.54 6.39e-11 Diabetic kidney disease; TGCT cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.09 0.42 1.26e-6 Height; TGCT cis rs4332037 0.539 rs11763750 chr7:2080114 G/A cg25834613 chr7:1915315 MAD1L1 -0.51 -4.98 -0.41 2.11e-6 Bipolar disorder; TGCT cis rs11718455 0.960 rs1852036 chr3:44003862 C/T cg08738300 chr3:44038990 NA 0.87 6.61 0.51 1.02e-9 Coronary artery disease; TGCT cis rs875971 0.862 rs10240949 chr7:65804417 A/G cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.43e-7 Aortic root size; TGCT cis rs478304 0.651 rs948493 chr11:65552154 C/T cg10518572 chr11:65560635 OVOL1 -0.24 -4.44 -0.37 1.98e-5 Acne (severe); TGCT cis rs7662987 0.517 rs2851263 chr4:100030354 A/G cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs926938 0.584 rs2798663 chr1:115363582 G/A cg12756093 chr1:115239321 AMPD1 0.42 6.0 0.47 2.04e-8 Autism; TGCT cis rs2046867 0.908 rs11927166 chr3:72795149 C/G cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs2469997 0.800 rs2447177 chr8:120356431 A/G cg01792902 chr3:178864926 PIK3CA 0.84 6.81 0.52 3.74e-10 Hypertension (SNP x SNP interaction); TGCT cis rs9906944 0.898 rs9909861 chr17:47079416 C/A cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.8 -0.4 4.47e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs1525293 0.714 rs13227328 chr7:70500643 C/T cg21135135 chr7:70597687 WBSCR17 0.54 4.96 0.41 2.23e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs950169 0.544 rs12913702 chr15:85153184 G/A cg12863693 chr15:85201151 NMB 0.41 4.88 0.4 3.26e-6 Schizophrenia; TGCT cis rs854765 0.893 rs712265 chr17:18008447 G/A cg04398451 chr17:18023971 MYO15A 0.3 4.79 0.39 4.75e-6 Total body bone mineral density; TGCT cis rs12765878 0.967 rs7920217 chr10:105668172 C/T cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs2115630 0.755 rs7169629 chr15:85191274 C/G cg12501888 chr15:85177176 SCAND2 0.45 4.45 0.37 1.86e-5 P wave terminal force; TGCT cis rs835154 0.845 rs835158 chr5:14873254 C/G cg14843632 chr5:14870594 ANKH 0.33 4.57 0.38 1.16e-5 Blood metabolite levels; TGCT cis rs6490294 0.904 rs76300790 chr12:112402669 A/T cg10833066 chr12:111807467 FAM109A 0.35 4.49 0.37 1.58e-5 Mean platelet volume; TGCT cis rs586688 0.625 rs510576 chr1:201654962 G/T cg14168733 chr1:201708718 NAV1 -0.55 -4.44 -0.37 1.93e-5 Obesity-related traits; TGCT cis rs2239547 0.522 rs2581815 chr3:52982159 C/G cg11645453 chr3:52864694 ITIH4 0.33 5.42 0.44 2.94e-7 Schizophrenia; TGCT cis rs6547741 0.874 rs28381983 chr2:27804432 T/C cg27432699 chr2:27873401 GPN1 0.18 4.58 0.38 1.13e-5 Oral cavity cancer; TGCT cis rs9926296 0.581 rs2108838 chr16:89904426 A/G cg04287289 chr16:89883240 FANCA 0.72 7.39 0.55 1.87e-11 Vitiligo; TGCT cis rs62229266 0.682 rs2835224 chr21:37370030 A/T cg08632701 chr21:37451849 NA -0.15 -4.6 -0.38 1.03e-5 Mitral valve prolapse; TGCT cis rs922182 0.617 rs12324438 chr15:64243436 A/C cg02919090 chr15:64263738 DAPK2 -0.37 -6.84 -0.52 3.19e-10 Blood protein levels; TGCT cis rs6088590 0.603 rs6579186 chr20:33282198 G/C cg08999081 chr20:33150536 PIGU 0.26 4.88 0.4 3.17e-6 Coronary artery disease; TGCT cis rs6569992 0.500 rs11965249 chr6:135497692 G/C cg22676075 chr6:135203613 NA 0.75 4.64 0.38 8.82e-6 Red blood cell traits; TGCT cis rs3617 0.625 rs56019197 chr3:52874753 T/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.46 -0.37 1.83e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2963155 0.518 rs72801080 chr5:142751990 T/C cg17617527 chr5:142782415 NR3C1 0.8 5.78 0.46 5.8e-8 Breast cancer; TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.52 -4.91 -0.4 2.83e-6 Prudent dietary pattern; TGCT cis rs9467711 0.606 rs12174602 chr6:26372827 C/T cg16898833 chr6:26189333 HIST1H4D 1.13 5.38 0.43 3.63e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs3806843 0.966 rs2563265 chr5:140137005 C/T cg19875535 chr5:140030758 IK -0.35 -5.89 -0.47 3.46e-8 Depressive symptoms (multi-trait analysis); TGCT trans rs1379326 1.000 rs1379326 chr8:4617810 C/T cg01049870 chr14:95601239 DICER1 -0.22 -7.12 -0.54 7.72e-11 Interstitial lung disease; TGCT cis rs9733 0.596 rs6690725 chr1:150632322 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs9677476 0.863 rs60953838 chr2:232065864 G/C cg07929768 chr2:232055508 NA 0.31 4.5 0.37 1.53e-5 Food antigen IgG levels; TGCT cis rs13256369 1.000 rs12550762 chr8:8576535 T/A cg06671706 chr8:8559999 CLDN23 0.35 4.7 0.39 6.89e-6 Obesity-related traits; TGCT cis rs7647973 1.000 rs62259944 chr3:49430883 G/A cg06212747 chr3:49208901 KLHDC8B -0.58 -4.58 -0.38 1.11e-5 Menarche (age at onset); TGCT cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs12291225 0.535 rs16930126 chr11:14404983 C/T cg19336497 chr11:14380999 RRAS2 0.32 4.73 0.39 5.99e-6 Sense of smell; TGCT cis rs78456975 0.506 rs13402886 chr2:1575348 G/A cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9486719 0.857 rs1157316 chr6:96869710 G/A cg18709589 chr6:96969512 KIAA0776 0.75 6.3 0.49 4.73e-9 Migraine;Coronary artery disease; TGCT cis rs3118233 1 rs3118233 chr16:68733646 G/C cg01251360 chr16:68772225 CDH1 0.27 4.54 0.38 1.31e-5 Red cell distribution width; TGCT cis rs4975616 0.869 rs455433 chr5:1336243 A/G cg07493874 chr5:1342172 CLPTM1L -0.28 -6.88 -0.53 2.69e-10 Lung cancer; TGCT cis rs4711350 1.000 rs4711350 chr6:33741716 A/G cg00334056 chr6:33755658 LEMD2 -0.29 -4.65 -0.39 8.32e-6 Schizophrenia; TGCT cis rs231513 0.593 rs11654132 chr17:42149134 G/A cg26893861 chr17:41843967 DUSP3 0.84 5.02 0.41 1.74e-6 Cognitive function; TGCT cis rs4766566 0.694 rs3843673 chr12:111746499 A/G cg10833066 chr12:111807467 FAM109A 0.4 7.5 0.56 1.07e-11 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs587847 0.767 rs4924152 chr15:37665396 T/C cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs4984778 0.750 rs7198064 chr16:1272472 C/T cg09075268 chr16:1270372 CACNA1H 0.32 4.78 0.39 4.96e-6 Blood protein levels; TGCT cis rs11734570 0.581 rs55958238 chr4:38604331 A/G cg18361445 chr4:38666374 KLF3;FLJ13197 0.63 5.25 0.43 6.25e-7 Inflammatory bowel disease;Crohn's disease; TGCT cis rs4595586 0.563 rs2388178 chr12:39364366 T/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs992157 0.710 rs12996912 chr2:219110555 A/G cg00012203 chr2:219082015 ARPC2 0.81 9.98 0.67 1.41e-17 Colorectal cancer; TGCT cis rs10992471 0.702 rs10820967 chr9:95101729 C/G cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.61 -0.45 1.28e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9393692 0.645 rs766407 chr6:26319534 T/C cg13736514 chr6:26305472 NA -0.45 -6.67 -0.51 7.52e-10 Educational attainment; TGCT cis rs10504229 0.679 rs16921606 chr8:58034477 A/C cg08280861 chr8:58055591 NA 0.34 4.98 0.41 2.12e-6 Developmental language disorder (linguistic errors); TGCT cis rs11043280 0.703 rs11043275 chr12:122402723 T/C cg13699009 chr12:122356056 WDR66 0.3 6.21 0.49 7.23e-9 Mean platelet volume; TGCT cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg16680214 chr1:154839983 KCNN3 -0.36 -7.33 -0.55 2.59e-11 Prostate cancer; TGCT cis rs10509586 0.826 rs58207706 chr10:91899453 C/T cg25278353 chr10:91717815 NA 0.49 4.67 0.39 7.77e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs28595532 0.920 rs115334469 chr4:119596194 G/C cg11846333 chr4:119757529 SEC24D 0.95 4.68 0.39 7.54e-6 Cannabis dependence symptom count; TGCT cis rs709400 0.603 rs2296486 chr14:104003070 A/G cg12935359 chr14:103987150 CKB -0.37 -5.54 -0.45 1.73e-7 Body mass index; TGCT cis rs17741873 0.779 rs4746153 chr10:75598282 G/C cg07699608 chr10:75541558 CHCHD1 0.72 5.15 0.42 1.02e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs838147 0.537 rs485186 chr19:49207206 A/G cg04599840 chr19:48886497 KDELR1 0.22 4.58 0.38 1.14e-5 Dietary macronutrient intake; TGCT cis rs3796352 0.667 rs34860124 chr3:52857778 T/A cg07884673 chr3:53033167 SFMBT1 0.6 4.94 0.41 2.5e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3020333 0.755 rs851996 chr6:152016803 C/T cg22157087 chr6:152012887 ESR1 0.22 5.46 0.44 2.54e-7 Total body bone mineral density; TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg11494091 chr17:61959527 GH2 0.61 14.78 0.8 4.02e-29 Prudent dietary pattern; TGCT cis rs1801251 1.000 rs7606090 chr2:233606740 T/C cg25237894 chr2:233734115 C2orf82 0.31 5.62 0.45 1.21e-7 Coronary artery disease; TGCT cis rs67478160 0.643 rs11160762 chr14:104255083 A/G cg26031613 chr14:104095156 KLC1 0.64 6.58 0.51 1.2e-9 Schizophrenia; TGCT cis rs7662987 0.517 rs1133485 chr4:100023811 T/A cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs12188164 0.931 rs115554641 chr5:443236 C/G cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs28595532 0.920 rs116795224 chr4:119734570 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs7772486 0.738 rs75288066 chr6:146319386 C/A cg23711669 chr6:146136114 FBXO30 0.84 8.53 0.61 4.35e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 0.965 rs8176198 chr17:41230537 A/T cg10047753 chr17:41438598 NA 0.69 5.71 0.46 7.78e-8 Menopause (age at onset); TGCT cis rs4654899 1.000 rs2271115 chr1:21295864 C/T cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs1552244 0.751 rs12715665 chr3:10021601 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs6089584 0.888 rs6061981 chr20:60618973 T/C cg13665807 chr20:60559372 TAF4 -0.46 -5.0 -0.41 1.92e-6 Body mass index; TGCT cis rs80282103 0.867 rs17155821 chr10:1071701 A/G cg08668510 chr10:1095578 IDI1 1.17 5.46 0.44 2.53e-7 Glomerular filtration rate (creatinine); TGCT cis rs2072499 0.966 rs1060604 chr1:156184268 T/C cg24450063 chr1:156163899 SLC25A44 1.18 13.56 0.77 2.93e-26 Testicular germ cell tumor; TGCT cis rs7582180 0.568 rs10186134 chr2:100939501 T/A cg08017756 chr2:100939284 LONRF2 -0.3 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.767 rs1536833 chr10:30699265 C/T cg13289132 chr10:30722225 MAP3K8 0.43 5.31 0.43 4.94e-7 Inflammatory bowel disease; TGCT cis rs7528419 0.632 rs11102967 chr1:109817245 C/T cg00908766 chr1:109817496 CELSR2 0.47 4.79 0.39 4.73e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs7010267 0.570 rs4305930 chr8:120058021 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.62 0.38 9.29e-6 Total body bone mineral density (age 45-60); TGCT cis rs734999 0.505 rs10797438 chr1:2540262 C/T cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs6121246 0.529 rs7261354 chr20:30202414 T/C cg13852791 chr20:30311386 BCL2L1 0.7 4.68 0.39 7.29e-6 Mean corpuscular hemoglobin; TGCT cis rs7917772 0.503 rs7068535 chr10:104349127 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 8.21 0.59 2.44e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9467773 0.596 rs3001369 chr6:26670969 C/T cg05738196 chr6:26577821 NA 0.89 10.01 0.67 1.22e-17 Intelligence (multi-trait analysis); TGCT cis rs9457247 0.846 rs2757052 chr6:167380174 T/C cg25258033 chr6:167368657 RNASET2 -0.18 -4.49 -0.37 1.63e-5 Crohn's disease; TGCT cis rs1008375 0.966 rs4698642 chr4:17679174 A/T cg16339924 chr4:17578868 LAP3 0.52 4.57 0.38 1.16e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg16325326 chr1:53192061 ZYG11B 0.6 6.77 0.52 4.62e-10 Monocyte count; TGCT cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg18252515 chr7:66147081 NA 1.24 7.65 0.57 4.78e-12 Diabetic kidney disease; TGCT cis rs8084125 0.832 rs62105168 chr18:74944848 T/C cg05528293 chr18:74961138 GALR1 0.49 4.84 0.4 3.74e-6 Obesity-related traits; TGCT cis rs3782123 0.604 rs11245998 chr11:207462 A/G cg18336825 chr11:236787 PSMD13;SIRT3 -0.51 -4.6 -0.38 1.01e-5 Glycated hemoglobin levels;Red cell distribution width; TGCT cis rs981844 0.816 rs62325147 chr4:154727568 G/A cg14289246 chr4:154710475 SFRP2 1.03 9.04 0.63 2.61e-15 Response to statins (LDL cholesterol change); TGCT cis rs9303401 0.659 rs36093395 chr17:56957357 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs1005277 0.579 rs1780137 chr10:38501475 C/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.51 -0.61 4.69e-14 Extrinsic epigenetic age acceleration; TGCT cis rs826838 0.935 rs1684407 chr12:39127270 C/T cg13010199 chr12:38710504 ALG10B -0.63 -5.04 -0.41 1.6e-6 Heart rate; TGCT cis rs12142240 0.659 rs67547686 chr1:46832229 G/C cg00530320 chr1:46809349 NSUN4 0.29 6.03 0.48 1.71e-8 Menopause (age at onset); TGCT cis rs8103278 0.894 rs74821481 chr19:46320041 G/T cg14061069 chr19:46274453 DMPK -0.44 -6.12 -0.48 1.11e-8 Coronary artery disease; TGCT cis rs3096299 0.748 rs3102339 chr16:89442711 C/T cg06640241 chr16:89574553 SPG7 0.62 5.74 0.46 6.96e-8 Multiple myeloma (IgH translocation); TGCT cis rs7760949 0.925 rs9464420 chr6:13925892 C/T cg27413430 chr6:13925136 RNF182 0.74 6.93 0.53 2.06e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs910316 1.000 rs7156105 chr14:75541954 C/A cg23033748 chr14:75592666 NEK9 0.28 4.64 0.38 8.6e-6 Height; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs7027203 0.663 rs4428726 chr9:96623559 T/G cg14598338 chr9:96623480 NA -0.63 -10.08 -0.67 8.11e-18 DNA methylation (variation); TGCT cis rs7582180 0.614 rs4340543 chr2:101005511 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.81 0.4 4.21e-6 Intelligence (multi-trait analysis); TGCT cis rs250677 1.000 rs36082 chr5:148428844 C/G cg18129178 chr5:148520854 ABLIM3 -0.4 -5.54 -0.45 1.72e-7 Breast cancer; TGCT cis rs35146811 0.844 rs4729576 chr7:99692594 G/A cg22906224 chr7:99728672 NA 0.51 4.5 0.37 1.56e-5 Coronary artery disease; TGCT cis rs1670533 1.000 rs6857085 chr4:1095920 C/A cg20518497 chr4:1046821 NA 0.27 4.46 0.37 1.82e-5 Recombination rate (females); TGCT cis rs7267979 1.000 rs4815409 chr20:25346697 C/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8078723 1.000 rs7214085 chr17:38169095 T/C cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7582180 0.577 rs6542942 chr2:100985378 G/T cg08017756 chr2:100939284 LONRF2 -0.29 -4.62 -0.38 9.62e-6 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.503 rs11191320 chr10:104293394 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8062405 0.720 rs9926245 chr16:28555706 T/A cg09754948 chr16:28834200 ATXN2L 0.63 5.05 0.41 1.52e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs61990749 0.597 rs11623088 chr14:78137735 G/A cg02301378 chr14:78227641 SNW1;C14orf178 -0.63 -4.62 -0.38 9.31e-6 Fibroblast growth factor basic levels; TGCT cis rs2066819 1.000 rs1802236 chr12:56679751 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs769267 0.895 rs2916073 chr19:19528324 T/G cg03709012 chr19:19516395 GATAD2A 0.74 6.29 0.49 4.89e-9 Tonsillectomy; TGCT cis rs3008870 0.583 rs2147838 chr1:67399466 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.97 8.18 0.59 2.82e-13 Lymphocyte percentage of white cells; TGCT cis rs231513 0.954 rs11654245 chr17:41992650 T/C cg26893861 chr17:41843967 DUSP3 0.77 5.46 0.44 2.5e-7 Cognitive function; TGCT cis rs1857353 1.000 rs17584320 chr1:75879593 C/T cg11838876 chr1:75668600 SLC44A5 -0.45 -4.49 -0.37 1.58e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs28595532 0.920 rs115240535 chr4:119745395 G/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs3960554 0.808 rs59882870 chr7:75638421 G/A cg17325771 chr7:75508891 RHBDD2 -0.55 -4.63 -0.38 9.19e-6 Eotaxin levels; TGCT cis rs2594989 0.670 rs9845397 chr3:11470263 C/T cg00170343 chr3:11313890 ATG7 0.79 5.8 0.46 5.18e-8 Circulating chemerin levels; TGCT trans rs1814175 0.765 rs1794141 chr11:49914135 G/C cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs12681288 0.862 rs2600493 chr8:1024970 A/G cg06709756 chr8:1339049 NA -0.23 -4.49 -0.37 1.62e-5 Schizophrenia; TGCT cis rs1697139 0.604 rs874550 chr5:66530945 C/T cg11553311 chr5:66541588 NA -0.3 -6.07 -0.48 1.42e-8 Breast cancer; TGCT cis rs7666738 0.830 rs9992391 chr4:98916052 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.2 0.54 5.03e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6866344 0.570 rs4266420 chr5:178137161 C/G cg10224037 chr5:178157518 ZNF354A 0.95 9.38 0.64 3.96e-16 Neutrophil percentage of white cells; TGCT cis rs929354 0.772 rs1182362 chr7:157019535 A/G cg05182265 chr7:156933206 UBE3C 0.4 9.08 0.63 2.11e-15 Body mass index; TGCT cis rs4595586 0.505 rs12827136 chr12:39412790 C/T cg26384229 chr12:38710491 ALG10B 0.56 4.5 0.37 1.56e-5 Morning vs. evening chronotype; TGCT cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg26818010 chr10:134567672 INPP5A -0.38 -5.22 -0.42 7.33e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg12310025 chr6:25882481 NA 0.52 5.34 0.43 4.19e-7 Blood metabolite levels; TGCT cis rs6430585 0.527 rs1900306 chr2:136416533 G/A cg07169764 chr2:136633963 MCM6 1.04 9.13 0.63 1.63e-15 Corneal structure; TGCT cis rs1483890 0.723 rs12629229 chr3:69411222 A/G cg22125112 chr3:69402811 FRMD4B 0.29 4.92 0.4 2.66e-6 Resting heart rate; TGCT cis rs986417 0.901 rs1989477 chr14:61024867 T/C cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs6988636 1.000 rs16898097 chr8:124195034 G/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs992157 0.764 rs2015863 chr2:219185161 C/T cg00012203 chr2:219082015 ARPC2 -0.75 -6.84 -0.52 3.23e-10 Colorectal cancer; TGCT cis rs1153858 0.621 rs2413769 chr15:45561868 A/C cg26924012 chr15:45694286 SPATA5L1 1.0 10.41 0.68 1.28e-18 Homoarginine levels; TGCT cis rs3796352 1.000 rs60942590 chr3:53016421 G/A cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2204008 0.743 rs2132212 chr12:38039405 G/A cg26384229 chr12:38710491 ALG10B 0.7 6.14 0.48 1.04e-8 Bladder cancer; TGCT cis rs2180341 0.961 rs7775493 chr6:127615000 C/A cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs12220238 0.915 rs11001027 chr10:76152655 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.17 0.48 9.08e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs6121246 0.542 rs6059761 chr20:30110522 G/C cg10886678 chr20:30946050 ASXL1 -0.7 -4.65 -0.39 8.46e-6 Mean corpuscular hemoglobin; TGCT cis rs7192750 0.586 rs4788581 chr16:71967695 T/A cg06353428 chr16:71660113 MARVELD3 0.77 6.82 0.52 3.61e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7043114 0.525 rs10739927 chr9:95052081 G/T cg14631576 chr9:95140430 CENPP -0.28 -4.65 -0.39 8.23e-6 Height; TGCT cis rs793571 0.536 rs7183336 chr15:58966236 C/T cg05156742 chr15:59063176 FAM63B 0.54 5.22 0.42 7.16e-7 Schizophrenia; TGCT cis rs8070128 0.600 rs8071238 chr17:17900990 T/C cg04398451 chr17:18023971 MYO15A -0.34 -5.39 -0.44 3.34e-7 Total body bone mineral density; TGCT cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg04267008 chr7:1944627 MAD1L1 -0.35 -4.44 -0.37 2e-5 Bipolar disorder and schizophrenia; TGCT cis rs9583531 0.891 rs7999536 chr13:111382199 G/A cg24331049 chr13:111365604 ING1 0.76 5.3 0.43 5.03e-7 Coronary artery disease; TGCT cis rs7208859 0.623 rs76633166 chr17:29113365 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4689388 0.581 rs4688985 chr4:6285715 A/G cg14416269 chr4:6271139 WFS1 0.47 5.65 0.45 1.07e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3617 0.573 rs9850563 chr3:52912214 G/A cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.88 0.4 3.15e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs826838 1.000 rs11183941 chr12:38851692 G/C cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs40363 0.671 rs4786425 chr16:3537650 A/G cg22508957 chr16:3507546 NAT15 -0.51 -4.54 -0.38 1.29e-5 Tuberculosis; TGCT cis rs7809950 0.954 rs3779494 chr7:107250355 G/A cg23024343 chr7:107201750 COG5 0.33 5.29 0.43 5.36e-7 Coronary artery disease; TGCT cis rs10875595 0.836 rs62378923 chr5:140656398 C/T cg20560182 chr5:140700478 TAF7 -0.66 -5.06 -0.41 1.49e-6 Pulmonary function decline; TGCT cis rs2120019 0.935 rs34835684 chr15:75331805 T/G cg11632617 chr15:75315747 PPCDC -0.3 -4.47 -0.37 1.71e-5 Blood trace element (Zn levels); TGCT cis rs6570726 0.846 rs6899900 chr6:145883873 T/G cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs1865760 0.713 rs1130000 chr6:25985396 A/G cg17042849 chr6:26104293 HIST1H4C -0.55 -4.8 -0.4 4.4e-6 Height; TGCT cis rs10193935 0.901 rs13426988 chr2:42604081 G/A cg27598129 chr2:42591480 NA -0.4 -4.67 -0.39 7.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.693 rs9915776 chr17:17749056 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.71 -6.75 -0.52 5.19e-10 Total body bone mineral density; TGCT cis rs9952991 0.882 rs2847274 chr18:12777603 T/C cg23598886 chr18:12777645 NA 0.62 5.9 0.47 3.25e-8 Inflammatory skin disease; TGCT cis rs35306767 0.714 rs12767171 chr10:1084491 A/G cg26597838 chr10:835615 NA 0.48 5.44 0.44 2.75e-7 Eosinophil percentage of granulocytes; TGCT cis rs12510870 0.599 rs1528917 chr4:74452502 G/C cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs4819052 0.851 rs2838857 chr21:46681000 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 6.9 0.53 2.41e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs79349575 0.721 rs3744608 chr17:46993233 C/G cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs7731657 0.569 rs12522693 chr5:130195731 G/A cg08523029 chr5:130500466 HINT1 -0.79 -5.06 -0.41 1.5e-6 Fasting plasma glucose; TGCT cis rs7246657 1.000 rs12709812 chr19:37794850 A/G cg18154014 chr19:37997991 ZNF793 -0.85 -5.93 -0.47 2.85e-8 Coronary artery calcification; TGCT cis rs2887571 1.000 rs4322451 chr12:1637963 C/T cg01940102 chr12:1095972 NA -0.26 -5.05 -0.41 1.52e-6 Bone mineral density; TGCT cis rs6121246 0.559 rs6060950 chr20:30378031 T/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs2180341 0.782 rs6924274 chr6:127721556 T/A cg24812749 chr6:127587940 RNF146 0.65 5.19 0.42 8.37e-7 Breast cancer; TGCT cis rs1577917 0.771 rs2842613 chr6:86305702 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 5.58 0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs9473924 0.505 rs2817332 chr6:50848522 T/A cg14470998 chr6:50812995 TFAP2B -1.35 -8.53 -0.61 4.26e-14 Body mass index; TGCT trans rs1814175 0.817 rs1988416 chr11:49932324 G/A cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT trans rs1005277 0.522 rs9417256 chr10:37976990 A/G cg17830980 chr10:43048298 ZNF37B -0.66 -7.47 -0.56 1.22e-11 Extrinsic epigenetic age acceleration; TGCT cis rs3780378 0.967 rs10815144 chr9:5010192 C/T cg02405213 chr9:5042618 JAK2 -0.56 -7.61 -0.56 5.94e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs4808199 0.948 rs2074301 chr19:19381715 G/A cg03709012 chr19:19516395 GATAD2A 0.8 6.14 0.48 1.03e-8 Nonalcoholic fatty liver disease; TGCT cis rs9916302 0.851 rs11657899 chr17:37626963 G/A cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs921968 0.545 rs2433738 chr2:219551036 T/A cg02176678 chr2:219576539 TTLL4 -0.33 -4.45 -0.37 1.92e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs733175 0.855 rs10018666 chr4:10004805 C/T cg00071950 chr4:10020882 SLC2A9 0.5 4.58 0.38 1.13e-5 Psychosis and Alzheimer's disease; TGCT cis rs4820539 0.902 rs4822359 chr22:23474972 A/G cg14186256 chr22:23484241 RTDR1 0.98 12.24 0.74 4.43e-23 Bone mineral density; TGCT cis rs7267979 1.000 rs2482940 chr20:25349830 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9322193 0.923 rs9322209 chr6:150012362 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.38 5.06 0.41 1.47e-6 Lymphocyte counts; TGCT trans rs1005277 0.579 rs1780133 chr10:38499509 T/C cg27523141 chr10:43048294 ZNF37B 0.7 8.17 0.59 3.04e-13 Extrinsic epigenetic age acceleration; TGCT cis rs797680 0.891 rs9432453 chr1:93771629 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.1 -0.42 1.24e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs3780486 0.846 rs7036812 chr9:33143822 T/C cg20290983 chr6:43655470 MRPS18A 1.19 14.23 0.79 7.61e-28 IgG glycosylation; TGCT cis rs9611565 0.625 rs12483991 chr22:41935285 A/G cg06634786 chr22:41940651 POLR3H -0.81 -8.05 -0.59 5.62e-13 Vitiligo; TGCT cis rs478304 0.580 rs11606947 chr11:65508237 A/C cg17480646 chr11:65405466 SIPA1 -0.56 -6.87 -0.53 2.74e-10 Acne (severe); TGCT cis rs7666738 0.830 rs2865990 chr4:99067399 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.953 rs59034808 chr8:58185337 T/C cg08280861 chr8:58055591 NA 0.32 4.49 0.37 1.63e-5 Developmental language disorder (linguistic errors); TGCT cis rs3780378 0.840 rs10119004 chr9:5071049 C/T cg02405213 chr9:5042618 JAK2 -0.58 -8.18 -0.59 2.91e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7647973 1.000 rs6446262 chr3:49401153 T/C cg07636037 chr3:49044803 WDR6 0.72 5.72 0.46 7.47e-8 Menarche (age at onset); TGCT cis rs11785400 0.793 rs11785376 chr8:143730412 C/T cg10596483 chr8:143751796 JRK 0.53 5.21 0.42 7.5e-7 Schizophrenia; TGCT cis rs6540559 0.673 rs17015224 chr1:209968918 G/A cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs11690935 0.851 rs6433319 chr2:172830953 C/T cg13550731 chr2:172543902 DYNC1I2 -0.81 -7.08 -0.54 9.26e-11 Schizophrenia; TGCT cis rs6484504 0.553 rs7113880 chr11:31279557 A/G cg14844989 chr11:31128820 NA -0.25 -4.84 -0.4 3.76e-6 Red blood cell count; TGCT cis rs908922 0.651 rs7529157 chr1:152531365 C/A cg20991723 chr1:152506922 NA 0.45 6.05 0.48 1.6e-8 Hair morphology; TGCT cis rs4711350 0.734 rs4713676 chr6:33722098 G/T cg13859433 chr6:33739653 LEMD2 0.29 4.55 0.38 1.24e-5 Schizophrenia; TGCT cis rs6714710 0.603 rs13023980 chr2:98502987 T/C cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs10510102 0.872 rs11498944 chr10:123698263 T/C cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs10207060 0.778 rs6543581 chr2:240702308 C/T cg24332364 chr2:240308692 HDAC4 -0.14 -4.61 -0.38 9.71e-6 Obesity-related traits; TGCT cis rs698813 0.604 rs4953077 chr2:44481207 C/T cg00619915 chr2:44497795 NA -0.25 -5.7 -0.46 8.13e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs754133 0.891 rs12426399 chr12:54419910 G/T cg16264616 chr12:54390824 NA 0.33 5.14 0.42 1.02e-6 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs11190604 0.767 rs10883477 chr10:102161396 A/G cg23241863 chr10:102295624 HIF1AN 0.6 4.6 0.38 1.02e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg03660710 chr22:50631079 TRABD 0.34 4.51 0.38 1.46e-5 Amyotrophic lateral sclerosis (sporadic); TGCT trans rs7726839 0.540 rs3749615 chr5:601485 C/T cg11887960 chr12:57824829 NA 1.18 9.81 0.66 3.7e-17 Obesity-related traits; TGCT cis rs9905704 0.647 rs11650809 chr17:56972741 A/G cg05425664 chr17:57184151 TRIM37 -0.57 -4.44 -0.37 1.97e-5 Testicular germ cell tumor; TGCT cis rs807669 0.749 rs361787 chr22:19263698 C/T cg02655711 chr22:19163373 SLC25A1 0.32 6.98 0.53 1.57e-10 Metabolite levels; TGCT cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg09174653 chr7:1063357 C7orf50;MIR339 -0.23 -4.48 -0.37 1.64e-5 Longevity;Endometriosis; TGCT cis rs7209700 0.547 rs7219925 chr17:45341640 G/C cg21624342 chr17:45890973 OSBPL7 0.19 4.77 0.39 5.02e-6 IgG glycosylation; TGCT cis rs9467773 0.873 rs9295698 chr6:26566099 T/A cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg15320075 chr8:145703422 NA -0.68 -6.82 -0.52 3.52e-10 Age at first birth; TGCT cis rs910316 0.737 rs175072 chr14:75502827 T/C cg08847533 chr14:75593920 NEK9 -0.82 -8.66 -0.61 2.07e-14 Height; TGCT cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg11301795 chr4:187892539 NA -0.3 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 0.673 rs17015218 chr1:209967915 A/G cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT cis rs4494114 0.936 rs9439092 chr1:39375157 T/G cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.18e-9 Blood protein levels; TGCT cis rs6089829 0.962 rs3899032 chr20:61658542 G/A cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7010267 0.596 rs6984572 chr8:120054168 G/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.62 0.38 9.52e-6 Total body bone mineral density (age 45-60); TGCT cis rs4566357 1.000 rs1317770 chr2:227911725 C/T cg11843606 chr2:227700838 RHBDD1 -0.59 -5.59 -0.45 1.35e-7 Coronary artery disease; TGCT cis rs6089829 0.925 rs11086152 chr20:61664656 T/C cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs425277 0.539 rs3128338 chr1:2046786 G/A cg24578937 chr1:2090814 PRKCZ -0.24 -5.7 -0.46 8.26e-8 Height; TGCT cis rs4886920 0.563 rs8039011 chr15:78078445 A/G cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.36e-6 Neuroticism; TGCT cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg17554472 chr22:41940697 POLR3H -0.47 -4.77 -0.39 5.13e-6 Vitiligo; TGCT cis rs73001065 0.636 rs73002960 chr19:19582992 C/T cg03709012 chr19:19516395 GATAD2A 0.9 4.77 0.39 5.17e-6 LDL cholesterol; TGCT cis rs899997 0.906 rs1994018 chr15:79025584 G/A cg04896959 chr15:78267971 NA -0.36 -4.86 -0.4 3.43e-6 Coronary artery disease or large artery stroke; TGCT cis rs16858210 0.647 rs12107414 chr3:183574548 G/C cg25686905 chr3:183603175 PARL -0.27 -4.58 -0.38 1.11e-5 Menopause (age at onset); TGCT cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT cis rs9733 0.519 rs11800855 chr1:150800995 G/A cg09365446 chr1:150670422 GOLPH3L 0.32 4.55 0.38 1.25e-5 Tonsillectomy; TGCT cis rs2153535 0.580 rs7743995 chr6:8496212 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg12756686 chr19:29218302 NA 0.76 6.49 0.5 1.85e-9 Methadone dose in opioid dependence; TGCT cis rs6500602 0.701 rs8129 chr16:4562351 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.91 0.47 3.1e-8 Schizophrenia; TGCT cis rs7659604 0.537 rs6815973 chr4:122663430 A/T cg20573242 chr4:122745356 CCNA2 -0.54 -4.45 -0.37 1.88e-5 Type 2 diabetes; TGCT cis rs28374715 0.578 rs72739630 chr15:41631064 G/A cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.83 -0.8 2.99e-29 Ulcerative colitis; TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg16325326 chr1:53192061 ZYG11B 0.63 7.34 0.55 2.51e-11 Monocyte count; TGCT cis rs908922 0.651 rs10888493 chr1:152503913 G/A cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.26e-9 Hair morphology; TGCT cis rs7208859 0.673 rs3764420 chr17:29164154 A/G cg14008862 chr17:28927542 LRRC37B2 0.71 4.57 0.38 1.16e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10876993 0.890 rs799575 chr12:58069107 A/G cg15848620 chr12:58087721 OS9 -0.72 -5.91 -0.47 3.12e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs28374715 0.578 rs17730589 chr15:41600878 T/C cg18705301 chr15:41695430 NDUFAF1 -0.91 -14.59 -0.79 1.13e-28 Ulcerative colitis; TGCT cis rs4389656 0.857 rs274679 chr5:6751426 A/C cg10857441 chr5:6722123 POLS -0.21 -4.55 -0.38 1.27e-5 Coronary artery disease; TGCT cis rs9969804 0.744 rs10117377 chr9:95552437 C/T cg13940029 chr9:95239186 CENPP;ASPN -0.16 -4.51 -0.38 1.5e-5 Height; TGCT cis rs447921 0.861 rs72860804 chr17:74413903 G/A cg09812376 chr17:74270190 QRICH2 -0.46 -4.6 -0.38 1.01e-5 Mitochondrial DNA levels; TGCT cis rs1018836 0.570 rs6471084 chr8:91463666 T/C cg16814680 chr8:91681699 NA -0.72 -7.15 -0.54 6.53e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs3743266 0.507 rs56261931 chr15:60731618 C/T cg18480781 chr15:60294291 NA 0.62 4.88 0.4 3.2e-6 Menarche (age at onset); TGCT cis rs7584330 0.910 rs7606177 chr2:238394913 G/C cg14458575 chr2:238380390 NA 0.42 6.37 0.5 3.39e-9 Prostate cancer; TGCT cis rs9902453 0.868 rs8066602 chr17:28523085 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs2153535 0.601 rs2327059 chr6:8447071 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs4888262 0.526 rs7191754 chr16:74610850 G/T cg01733217 chr16:74700730 RFWD3 0.69 6.99 0.53 1.51e-10 Testicular germ cell tumor; TGCT cis rs1799949 0.965 rs7223952 chr17:41194885 T/C cg10047753 chr17:41438598 NA 0.67 5.95 0.47 2.54e-8 Menopause (age at onset); TGCT cis rs713477 1.000 rs713477 chr14:55904426 C/A cg23573665 chr14:55907122 TBPL2 -0.28 -4.47 -0.37 1.76e-5 Pediatric bone mineral content (femoral neck); TGCT cis rs7085104 0.700 rs10786712 chr10:104596396 A/G cg15744005 chr10:104629667 AS3MT 0.43 5.48 0.44 2.26e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs586688 0.625 rs602668 chr1:201657709 A/G cg07139329 chr1:201708558 NAV1 0.5 5.37 0.43 3.76e-7 Obesity-related traits; TGCT cis rs7666738 0.830 rs4392515 chr4:98957431 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7255045 0.788 rs7250751 chr19:12962648 A/G cg06537894 chr19:12978706 MAST1 -0.49 -4.48 -0.37 1.69e-5 Mean corpuscular volume; TGCT cis rs9611565 0.546 rs739134 chr22:42089623 T/C cg06481639 chr22:41940642 POLR3H 0.73 6.62 0.51 9.76e-10 Vitiligo; TGCT cis rs832540 0.629 rs10055224 chr5:56081201 C/T cg24531977 chr5:56204891 C5orf35 0.5 5.08 0.42 1.34e-6 Coronary artery disease; TGCT cis rs3125734 0.633 rs10740068 chr10:63982254 A/C cg09941381 chr10:64027924 RTKN2 -0.36 -5.53 -0.44 1.83e-7 Rheumatoid arthritis; TGCT cis rs11190604 0.767 rs872290 chr10:102198879 G/A cg16342193 chr10:102329863 NA -0.41 -5.22 -0.42 7.22e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7267979 0.966 rs6107031 chr20:25350677 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2997447 0.761 rs61776582 chr1:26437262 A/C cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs7572733 0.555 rs6434954 chr2:198929716 T/C cg00792783 chr2:198669748 PLCL1 0.58 5.13 0.42 1.09e-6 Dermatomyositis; TGCT cis rs7666738 0.830 rs4699593 chr4:98980628 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs617219 0.698 rs7706045 chr5:78507910 T/G cg23514016 chr5:78407564 BHMT 0.35 5.44 0.44 2.78e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4689388 0.609 rs4688988 chr4:6287456 C/T cg25554036 chr4:6271136 WFS1 0.58 6.96 0.53 1.77e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9467773 0.967 rs9295694 chr6:26512994 A/T cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs868036 0.681 rs28626095 chr15:68066729 T/C cg05925327 chr15:68127851 NA -0.5 -4.86 -0.4 3.43e-6 Restless legs syndrome; TGCT cis rs35000415 0.688 rs17340542 chr7:128720045 C/T cg06242719 chr7:129414860 MIR183;MIR96 0.3 4.58 0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 5.59 0.45 1.39e-7 Mean platelet volume; TGCT cis rs9796 0.621 rs557864 chr15:41471358 T/C cg18705301 chr15:41695430 NDUFAF1 0.52 7.17 0.54 5.94e-11 Menopause (age at onset); TGCT cis rs6674970 1.000 rs61819219 chr1:151084375 C/G cg00003202 chr1:151319512 RFX5 -0.51 -4.46 -0.37 1.84e-5 Childhood ear infection; TGCT cis rs2933343 1.000 rs1680795 chr3:128620388 T/C cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs9381040 0.748 rs9357348 chr6:41154232 A/G cg03526776 chr6:41159608 TREML2 0.29 6.17 0.48 9.01e-9 Alzheimer's disease (late onset); TGCT cis rs4975709 0.589 rs4975744 chr5:1860049 A/G cg07747251 chr5:1868357 NA 0.39 5.11 0.42 1.19e-6 Cardiovascular disease risk factors; TGCT cis rs2075371 0.932 rs1862052 chr7:133981227 G/A cg11752832 chr7:134001865 SLC35B4 0.67 5.95 0.47 2.54e-8 Mean platelet volume; TGCT cis rs3749237 0.595 rs12489092 chr3:49550914 G/C cg07636037 chr3:49044803 WDR6 0.62 5.83 0.46 4.59e-8 Resting heart rate; TGCT cis rs9894429 0.789 rs35887231 chr17:79587126 G/A cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg06558623 chr16:89946397 TCF25 0.57 6.89 0.53 2.56e-10 Skin colour saturation; TGCT cis rs769267 0.929 rs34538000 chr19:19481379 G/T cg08509172 chr19:19383838 TM6SF2 0.35 4.69 0.39 7.2e-6 Tonsillectomy; TGCT cis rs67311347 1.000 rs67311347 chr3:40533243 G/A cg13683864 chr3:40499215 RPL14 -1.16 -10.84 -0.7 1.13e-19 Renal cell carcinoma; TGCT cis rs912057 0.609 rs1294431 chr6:6745003 G/C cg06612196 chr6:6737390 NA 0.47 6.65 0.51 8.22e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.11 13.91 0.78 4.47e-27 Height; TGCT cis rs6988636 1.000 rs62521841 chr8:124194625 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs6089829 0.925 rs6122087 chr20:61664553 T/C cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs5750830 0.649 rs6001588 chr22:39819049 G/C cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs8017423 0.647 rs12883000 chr14:90820557 G/A cg04374321 chr14:90722782 PSMC1 -0.56 -5.62 -0.45 1.19e-7 Mortality in heart failure; TGCT cis rs7113874 0.569 rs10840095 chr11:8627975 G/T cg14521421 chr11:8862019 ST5 -0.3 -4.61 -0.38 1e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs2288073 0.965 rs6545338 chr2:24422156 C/T cg05570707 chr2:24270316 C2orf44 -0.5 -4.47 -0.37 1.72e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs9372498 0.908 rs4551203 chr6:118693502 G/A cg18833306 chr6:118973337 C6orf204 -0.61 -4.81 -0.4 4.28e-6 Diastolic blood pressure; TGCT cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Cannabis dependence symptom count; TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.42 4.57 0.38 1.15e-5 Lymphocyte counts; TGCT cis rs12142240 0.698 rs41294456 chr1:46809782 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs7267979 0.586 rs6083776 chr20:25186116 G/A cg03522245 chr20:25566470 NINL 0.5 5.24 0.43 6.66e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs561341 1.000 rs521919 chr17:30298039 G/T cg20587970 chr11:113659929 NA -1.02 -11.06 -0.7 3.39e-20 Hip circumference adjusted for BMI; TGCT cis rs7666738 0.830 rs34164616 chr4:99015251 G/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7635838 0.617 rs346076 chr3:11292682 A/G cg00170343 chr3:11313890 ATG7 -0.66 -6.69 -0.51 7.01e-10 HDL cholesterol; TGCT cis rs644799 0.930 rs587123 chr11:95560539 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs763014 0.966 rs4984904 chr16:680809 C/G cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.12e-6 Height; TGCT cis rs13191362 1.000 rs34697913 chr6:163000187 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs694419 0.602 rs9944724 chr18:60184611 T/G cg13506219 chr18:60193840 ZCCHC2 -0.54 -4.9 -0.4 2.89e-6 Serum albumin level; TGCT cis rs12580194 0.593 rs7485979 chr12:55789043 A/T cg10672482 chr12:55725839 OR6C3 0.49 4.47 0.37 1.71e-5 Cancer; TGCT cis rs61990749 0.597 rs2299930 chr14:78163722 C/T cg02301378 chr14:78227641 SNW1;C14orf178 -0.6 -4.45 -0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs28785552 0.897 rs10424736 chr19:53239176 G/A cg22067481 chr19:53234126 ZNF611 -0.49 -7.05 -0.53 1.1e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs72627509 0.904 rs3796529 chr4:57797414 C/T cg26694713 chr4:57773883 REST 0.7 6.24 0.49 6.44e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs921943 0.554 rs163132 chr5:78285921 A/G cg26802063 chr5:78281964 ARSB 0.65 6.23 0.49 6.66e-9 Blood and toenail selenium levels;Blood trace element (Se levels); TGCT cis rs61867294 0.794 rs868009 chr10:106661592 G/A cg08000847 chr10:105880925 C10orf78 0.56 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs1629083 0.901 rs1793150 chr11:118127314 G/A cg16594165 chr11:118135105 MPZL2 -0.33 -4.59 -0.38 1.08e-5 Lung cancer; TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg21672276 chr3:44754072 ZNF502 -0.44 -4.85 -0.4 3.69e-6 Depressive symptoms; TGCT cis rs2228479 0.850 rs17233567 chr16:89813821 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs769267 0.930 rs751856 chr19:19602945 A/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs9916302 0.904 rs801419 chr17:37466327 A/G cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs892961 0.932 rs7224442 chr17:75413439 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs4786125 0.512 rs55818804 chr16:6930199 T/C cg03623568 chr16:6915990 A2BP1 -0.4 -5.63 -0.45 1.13e-7 Heart rate variability traits (SDNN); TGCT cis rs6429082 0.818 rs704722 chr1:235669988 G/A cg26050004 chr1:235667680 B3GALNT2 0.58 5.16 0.42 9.46e-7 Adiposity; TGCT cis rs10875746 0.859 rs3782910 chr12:48483507 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs1023500 0.551 rs2854837 chr22:42458481 G/A cg15557168 chr22:42548783 NA -0.2 -5.17 -0.42 9.05e-7 Schizophrenia; TGCT cis rs1488864 1.000 rs1812173 chr11:6342018 T/G cg12755421 chr11:6342214 PRKCDBP -0.57 -4.6 -0.38 1.02e-5 Smooth-surface caries; TGCT cis rs1937680 0.657 rs2339888 chr10:53634357 T/C cg13719243 chr10:52750743 PRKG1 0.34 4.69 0.39 7.06e-6 Breast cancer; TGCT cis rs2455799 0.559 rs6442552 chr3:15922740 T/C cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs736408 0.812 rs2240920 chr3:52831009 A/G cg07507251 chr3:52567010 NT5DC2 -0.42 -5.48 -0.44 2.24e-7 Bipolar disorder; TGCT cis rs1577917 0.682 rs6935918 chr6:86283575 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 4.65 0.39 8.31e-6 Response to antipsychotic treatment; TGCT cis rs7216064 1.000 rs60432293 chr17:65860407 T/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs10193935 0.786 rs10178087 chr2:42409631 C/A cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs56104184 0.775 rs73063505 chr19:49402765 T/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9914544 0.545 rs8077775 chr17:18809543 A/G cg26378065 chr17:18585709 ZNF286B 0.51 4.5 0.37 1.53e-5 Educational attainment (years of education); TGCT cis rs3087591 0.683 rs4368212 chr17:29639263 C/T cg24425628 chr17:29625626 OMG;NF1 0.4 6.04 0.48 1.69e-8 Hip circumference; TGCT cis rs10465746 0.746 rs12749350 chr1:84456948 T/A cg10977910 chr1:84465055 TTLL7 0.69 7.04 0.53 1.14e-10 Obesity-related traits; TGCT cis rs3099143 1.000 rs3110379 chr15:77095175 A/G cg21673338 chr15:77095150 SCAPER -0.51 -4.91 -0.4 2.85e-6 Recalcitrant atopic dermatitis; TGCT cis rs3776081 0.600 rs758588 chr5:149534730 G/A cg18424208 chr5:149546337 CDX1 -0.25 -4.53 -0.38 1.37e-5 Blood protein levels; TGCT cis rs3772130 0.961 rs34667636 chr3:121353291 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.55 4.95 0.41 2.35e-6 Cognitive performance; TGCT cis rs6840360 0.904 rs73862064 chr4:152503100 T/A cg17479576 chr4:152424074 FAM160A1 -0.55 -6.1 -0.48 1.22e-8 Intelligence (multi-trait analysis); TGCT cis rs12500482 0.935 rs2239736 chr4:2438929 T/C cg08330972 chr4:2403930 ZFYVE28 -0.33 -4.45 -0.37 1.86e-5 Cognitive function; TGCT cis rs1538970 0.962 rs2487442 chr1:45857176 C/G cg05343316 chr1:45956843 TESK2 -0.71 -5.5 -0.44 2.04e-7 Platelet count; TGCT cis rs9916302 0.904 rs8065963 chr17:37681332 C/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.92 -0.4 2.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.724 rs28451676 chr4:98966990 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.81e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10791111 1 rs10791111 chr11:130856099 T/G cg05962950 chr11:130786565 SNX19 0.71 6.87 0.52 2.8e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs597539 0.652 rs646586 chr11:68681653 C/T cg21963583 chr11:68658836 MRPL21 -0.3 -4.85 -0.4 3.64e-6 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11874712 1.000 rs1800639 chr18:43671240 G/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs7829975 0.682 rs7013471 chr8:8687325 A/G cg08975724 chr8:8085496 FLJ10661 -0.58 -5.18 -0.42 8.73e-7 Mood instability; TGCT cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg01017244 chr2:74357527 NA 0.37 5.06 0.41 1.48e-6 Gestational age at birth (maternal effect); TGCT cis rs9611565 0.571 rs7364123 chr22:42216326 A/G cg13695892 chr22:41940480 POLR3H -0.75 -6.79 -0.52 4.1e-10 Vitiligo; TGCT cis rs801193 1.000 rs3857688 chr7:66127806 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.13 -0.42 1.07e-6 Aortic root size; TGCT cis rs1018836 0.770 rs13266461 chr8:91652817 T/C cg16814680 chr8:91681699 NA -0.94 -11.83 -0.73 4.43e-22 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9291683 0.546 rs13139055 chr4:10038924 G/T cg11266682 chr4:10021025 SLC2A9 0.61 7.73 0.57 3.25e-12 Bone mineral density; TGCT cis rs227584 0.663 rs3180912 chr17:42259463 A/G cg19774624 chr17:42201019 HDAC5 -0.63 -6.55 -0.51 1.35e-9 Bone mineral density (hip);Bone mineral density; TGCT cis rs7267979 0.844 rs8184820 chr20:25250577 C/T cg16686733 chr20:25566563 NINL -0.52 -4.9 -0.4 2.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4870684 0.509 rs11763804 chr7:57702125 G/C cg01314568 chr7:57830625 NA -0.4 -5.01 -0.41 1.83e-6 Bipolar disorder and schizophrenia; TGCT cis rs6121246 0.511 rs879982 chr20:30398510 A/G cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs66573146 0.808 rs56268690 chr4:6923887 C/T cg05069807 chr4:6945702 TBC1D14 0.29 4.62 0.38 9.44e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1784581 0.588 rs4131681 chr6:162422167 T/G cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs1371867 0.875 rs1788187 chr8:101336099 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs78487399 0.710 rs6759383 chr2:43805228 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9303401 0.659 rs1864754 chr17:56688789 G/T cg10487724 chr17:56770010 TEX14;RAD51C -0.7 -6.65 -0.51 8.41e-10 Cognitive test performance; TGCT cis rs644799 0.931 rs496305 chr11:95567035 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.88 9.59 0.65 1.24e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9527 0.615 rs1556960 chr10:104726673 A/G cg15744005 chr10:104629667 AS3MT -0.45 -5.24 -0.43 6.54e-7 Arsenic metabolism; TGCT cis rs1555895 0.543 rs749297 chr10:861837 A/G cg02193355 chr10:851439 NA 0.24 5.4 0.44 3.29e-7 Survival in rectal cancer; TGCT cis rs2224391 0.590 rs2773312 chr6:5251798 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs2204008 0.654 rs1733410 chr12:38132172 G/A cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs782590 0.935 rs2627776 chr2:55873301 T/A cg03859395 chr2:55845619 SMEK2 0.93 11.2 0.71 1.53e-20 Metabolic syndrome; TGCT cis rs11098499 0.820 rs13128602 chr4:120459366 C/T cg09307838 chr4:120376055 NA -0.67 -6.25 -0.49 6.01e-9 Corneal astigmatism; TGCT cis rs2197308 0.643 rs1842597 chr12:37862142 C/G cg26384229 chr12:38710491 ALG10B -0.68 -6.18 -0.48 8.65e-9 Morning vs. evening chronotype; TGCT cis rs11249608 0.636 rs6888539 chr5:178449010 T/A cg01312482 chr5:178451176 ZNF879 -0.58 -5.77 -0.46 5.94e-8 Pubertal anthropometrics; TGCT cis rs3806843 0.766 rs801399 chr5:140034844 C/T cg19875535 chr5:140030758 IK -0.35 -5.93 -0.47 2.81e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9430161 0.579 rs77578010 chr1:11035758 G/A cg02454025 chr1:11042201 C1orf127 0.95 10.87 0.7 9.69e-20 Ewing sarcoma; TGCT cis rs9811920 0.809 rs793437 chr3:99559854 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.2 0.42 7.91e-7 Axial length; TGCT cis rs2652822 0.571 rs11858666 chr15:63526239 G/C cg12855773 chr15:63363890 TPM1 -0.16 -4.62 -0.38 9.42e-6 Metabolic traits; TGCT cis rs2486012 0.579 rs6680338 chr1:44246356 G/A cg12908607 chr1:44402522 ARTN -0.77 -4.96 -0.41 2.3e-6 Intelligence (multi-trait analysis); TGCT cis rs10782582 0.609 rs12138898 chr1:76375183 G/T cg03433033 chr1:76189801 ACADM -0.5 -4.91 -0.4 2.85e-6 Daytime sleep phenotypes; TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.56 -5.32 -0.43 4.76e-7 Prudent dietary pattern; TGCT cis rs10479542 0.929 rs10074573 chr5:178976966 C/T cg21226059 chr5:178986404 RUFY1 -0.45 -4.91 -0.4 2.84e-6 Lung cancer; TGCT cis rs4889855 0.614 rs9892081 chr17:78484484 A/C cg16591659 chr17:78472290 NA 0.34 5.51 0.44 1.99e-7 Fractional excretion of uric acid; TGCT cis rs9311474 0.652 rs352161 chr3:52221849 C/A cg10802521 chr3:52805072 NEK4 -0.59 -6.41 -0.5 2.81e-9 Electroencephalogram traits; TGCT cis rs1153858 1.000 rs12593230 chr15:45646968 A/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs6967414 0.685 rs6944332 chr7:6758018 G/A cg09896999 chr7:6746977 ZNF12 -0.59 -6.54 -0.51 1.45e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs2276314 1.000 rs2298715 chr18:33552425 T/C cg05985134 chr18:33552581 C18orf21 0.56 4.93 0.4 2.57e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs6964587 1.000 rs7802788 chr7:91736874 A/G cg17063962 chr7:91808500 NA 0.88 9.58 0.65 1.33e-16 Breast cancer; TGCT cis rs4273100 0.646 rs4924990 chr17:19294824 G/T cg01534423 chr17:18965556 NA -0.86 -6.37 -0.5 3.33e-9 Schizophrenia; TGCT cis rs3806843 0.966 rs10036519 chr5:140151701 C/T cg19875535 chr5:140030758 IK -0.37 -6.43 -0.5 2.45e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs10838634 1.000 rs59197251 chr11:46844849 C/T cg18332754 chr11:46939436 LRP4 0.94 4.84 0.4 3.83e-6 Schizophrenia; TGCT cis rs55823223 0.564 rs12103594 chr17:73855279 C/T cg08125733 chr17:73851984 WBP2 0.86 8.13 0.59 3.76e-13 Psoriasis; TGCT cis rs4319547 0.656 rs10773088 chr12:122828069 A/T cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.68 -0.39 7.27e-6 Body mass index; TGCT cis rs3820068 0.581 rs72645893 chr1:15930943 C/G cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs864745 0.967 rs849134 chr7:28196222 A/G cg23620719 chr7:28220237 JAZF1 -0.49 -4.56 -0.38 1.22e-5 Crohn's disease;Type 2 diabetes; TGCT cis rs1403694 0.695 rs10439971 chr3:186434188 C/T cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg07424592 chr7:64974309 NA 1.32 8.26 0.6 1.86e-13 Diabetic kidney disease; TGCT cis rs4642101 0.618 rs7612317 chr3:12820558 C/T cg05775895 chr3:12838266 CAND2 0.92 11.11 0.71 2.53e-20 QRS complex (12-leadsum); TGCT cis rs12908161 1.000 rs36033486 chr15:85319692 A/G cg17173187 chr15:85201210 NMB 0.57 6.4 0.5 2.89e-9 Schizophrenia; TGCT cis rs12220238 1.000 rs11000912 chr10:75948477 A/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9868809 1.000 rs2310997 chr3:48678011 G/C cg00383909 chr3:49044727 WDR6 0.96 4.76 0.39 5.32e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9811920 0.638 rs796978 chr3:99564321 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 7.02 0.53 1.32e-10 Axial length; TGCT cis rs9677476 0.516 rs3769989 chr2:232011440 C/A cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg11494091 chr17:61959527 GH2 0.6 14.48 0.79 1.94e-28 Prudent dietary pattern; TGCT cis rs10089 1.000 rs1559263 chr5:127512873 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.4 0.55 1.83e-11 Ileal carcinoids; TGCT cis rs6088580 0.634 rs6087579 chr20:32985155 A/G cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs2730245 1.000 rs2730241 chr7:158723014 T/C cg11984989 chr7:158649758 WDR60 -0.91 -8.06 -0.59 5.48e-13 Height; TGCT cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs10782582 0.609 rs1770882 chr1:76411549 G/A cg03433033 chr1:76189801 ACADM -0.52 -5.06 -0.41 1.44e-6 Daytime sleep phenotypes; TGCT cis rs137603 0.603 rs137581 chr22:39677838 C/T cg17798944 chr22:39715225 SNORD43;RPL3 -0.66 -6.79 -0.52 4.04e-10 Primary biliary cholangitis; TGCT cis rs9549367 0.713 rs3024769 chr13:113825601 A/C cg00898013 chr13:113819073 PROZ 0.54 7.1 0.54 8.57e-11 Platelet distribution width; TGCT trans rs57221529 0.766 rs12521051 chr5:560440 A/G cg11887960 chr12:57824829 NA -1.11 -8.99 -0.63 3.47e-15 Lung disease severity in cystic fibrosis; TGCT cis rs9921338 0.961 rs7187870 chr16:11431919 T/C cg00044050 chr16:11439710 C16orf75 -0.88 -6.75 -0.52 5.08e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs12681288 0.578 rs73176535 chr8:971916 C/T cg04851639 chr8:1020857 NA -0.31 -5.11 -0.42 1.17e-6 Schizophrenia; TGCT cis rs7447593 0.626 rs3812036 chr5:176813404 C/T cg17509989 chr5:176798049 RGS14 0.63 7.75 0.57 2.85e-12 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs2204008 0.640 rs2320744 chr12:38162389 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT cis rs9653442 0.564 rs2164711 chr2:100775422 G/T cg22139774 chr2:100720529 AFF3 -0.34 -5.4 -0.44 3.21e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs9929218 0.551 rs2296406 chr16:68721340 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.63 8.27 0.6 1.74e-13 Colorectal cancer; TGCT cis rs904251 0.797 rs2776878 chr6:37487273 G/A cg01843034 chr6:37503916 NA -0.52 -6.28 -0.49 5.17e-9 Cognitive performance; TGCT cis rs2956278 0.610 rs2929743 chr12:84691484 C/T cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs7267979 0.745 rs6132845 chr20:25547767 A/G cg16686733 chr20:25566563 NINL 0.54 5.32 0.43 4.66e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1005277 0.577 rs4934906 chr10:38015028 C/T cg25427524 chr10:38739819 LOC399744 -0.34 -6.73 -0.52 5.64e-10 Extrinsic epigenetic age acceleration; TGCT cis rs4631830 0.733 rs4512771 chr10:51540906 C/A cg10326726 chr10:51549505 MSMB -0.26 -5.22 -0.42 7.19e-7 Prostate-specific antigen levels; TGCT cis rs8044995 0.563 rs1110572 chr16:68396119 A/G cg05110241 chr16:68378359 PRMT7 -0.36 -4.44 -0.37 1.93e-5 Schizophrenia; TGCT cis rs9926296 0.586 rs1800359 chr16:89805261 A/G cg04287289 chr16:89883240 FANCA 0.66 6.56 0.51 1.33e-9 Vitiligo; TGCT cis rs12776158 0.901 rs57028689 chr10:71216345 G/A cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs6089829 1.000 rs6089829 chr20:61669036 C/T cg08045932 chr20:61659980 NA -0.48 -8.73 -0.62 1.41e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7923609 1.000 rs4595427 chr10:65012944 A/C cg08743896 chr10:65200160 JMJD1C -0.34 -4.54 -0.38 1.32e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs288326 0.561 rs77535302 chr2:183870045 T/A cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs17270561 0.779 rs12210620 chr6:25884785 T/C cg17691542 chr6:26056736 HIST1H1C 0.87 6.0 0.47 2.02e-8 Iron status biomarkers; TGCT cis rs2235642 0.859 rs9927529 chr16:1619488 C/T cg11375102 chr16:1583810 IFT140;TMEM204 -0.31 -5.06 -0.41 1.44e-6 Coronary artery disease; TGCT cis rs1971762 0.527 rs1683151 chr12:53946219 C/G cg16917193 chr12:54089295 NA -1.05 -10.82 -0.7 1.3e-19 Height; TGCT cis rs40363 0.620 rs1137454 chr16:3533577 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.61 4.51 0.38 1.5e-5 Tuberculosis; TGCT cis rs13108904 0.517 rs13128825 chr4:1334007 G/A cg03303774 chr4:1407052 NA 0.38 6.07 0.48 1.45e-8 Obesity-related traits; TGCT cis rs2836633 1.000 rs11088437 chr21:40053372 A/G cg05519781 chr21:40033154 ERG 0.69 6.61 0.51 1e-9 Coronary artery disease; TGCT trans rs916888 0.821 rs199507 chr17:44858855 A/G cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2404602 0.647 rs11072610 chr15:76930805 C/A cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs12477438 0.871 rs13396584 chr2:99611768 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.6 4.61 0.38 1e-5 Chronic sinus infection; TGCT cis rs7089973 0.604 rs10490909 chr10:116593532 C/T cg03647239 chr10:116582469 FAM160B1 0.61 5.86 0.47 3.92e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs6912958 0.535 rs1753153 chr6:88032834 T/G cg08069147 chr6:88032118 GJB7;C6orf162 0.72 7.32 0.55 2.77e-11 Monocyte percentage of white cells; TGCT cis rs1903068 0.853 rs9312655 chr4:56002665 T/C cg01777861 chr4:56023843 NA 0.53 6.21 0.49 7.2e-9 Endometriosis; TGCT cis rs9902453 0.726 rs3115088 chr17:28031275 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.39 0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs265548 0.646 rs36692 chr19:17906839 C/T cg04517722 chr19:17905589 B3GNT3 0.46 5.94 0.47 2.62e-8 Tumor biomarkers; TGCT cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg15687855 chr3:44754131 ZNF502 -0.43 -5.24 -0.43 6.74e-7 Depressive symptoms; TGCT cis rs1577917 0.771 rs4441928 chr6:86241894 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.64 5.56 0.45 1.55e-7 Response to antipsychotic treatment; TGCT cis rs9549367 0.713 rs2480949 chr13:113853149 T/C cg18105134 chr13:113819100 PROZ 0.46 8.58 0.61 3.25e-14 Platelet distribution width; TGCT cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs16854884 0.683 rs10935505 chr3:143777966 T/C cg06585982 chr3:143692056 C3orf58 0.54 4.54 0.38 1.34e-5 Economic and political preferences (feminism/equality); TGCT cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg16325326 chr1:53192061 ZYG11B -0.85 -11.92 -0.73 2.72e-22 Monocyte count; TGCT cis rs4383453 0.539 rs903572 chr3:123101144 A/G cg04890266 chr3:123102914 ADCY5 -0.48 -7.9 -0.58 1.25e-12 Gestational age at birth (maternal effect); TGCT cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs2188554 0.798 rs111495663 chr7:116984746 A/G cg09181792 chr7:117119393 CFTR 0.57 4.54 0.38 1.34e-5 Esophageal adenocarcinoma; TGCT cis rs10493773 0.862 rs12075929 chr1:86248138 A/C cg17807903 chr1:86174739 ZNHIT6 0.39 5.16 0.42 9.7e-7 Urate levels in overweight individuals; TGCT cis rs9300255 0.568 rs1790108 chr12:123636841 A/G cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs4888262 0.526 rs7191754 chr16:74610850 G/T cg05423758 chr16:74752063 FA2H 0.16 4.47 0.37 1.74e-5 Testicular germ cell tumor; TGCT cis rs4925386 0.840 rs6143024 chr20:60914229 A/G cg06026331 chr20:60912101 LAMA5 0.39 6.51 0.5 1.69e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs11096990 0.892 rs1901404 chr4:39212610 A/C ch.4.37949012R chr4:38272617 NA -0.38 -4.67 -0.39 7.77e-6 Cognitive function; TGCT cis rs116095464 0.558 rs10036253 chr5:238519 A/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs28595532 0.841 rs114155681 chr4:119736427 A/G cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs7772486 0.846 rs6908063 chr6:146403618 T/C cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2980439 0.556 rs2921059 chr8:8317887 G/T cg08975724 chr8:8085496 FLJ10661 0.57 5.19 0.42 8.42e-7 Neuroticism; TGCT cis rs931127 0.719 rs7949980 chr11:65445950 T/C cg27068330 chr11:65405492 SIPA1 -0.63 -6.18 -0.49 8.33e-9 Systemic lupus erythematosus; TGCT cis rs3782455 1.000 rs75235459 chr12:114400776 C/T cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2067615 0.507 rs11113083 chr12:107073316 C/A cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs6025261 0.788 rs6064468 chr20:55505301 A/C cg04763273 chr20:55502381 NA 0.3 4.6 0.38 1.02e-5 Verbal memory performance (delayed recall level); TGCT cis rs10489202 0.633 rs4657734 chr1:168086743 C/T cg24449463 chr1:168025552 DCAF6 -0.45 -4.66 -0.39 7.92e-6 Schizophrenia; TGCT cis rs1577917 1.000 rs2324843 chr6:86617501 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.46 -0.44 2.51e-7 Response to antipsychotic treatment; TGCT cis rs6748734 0.948 rs9973366 chr2:241838151 T/C cg04034577 chr2:241836375 C2orf54 -0.41 -6.31 -0.49 4.55e-9 Urinary metabolites; TGCT cis rs4711350 1.000 rs751727 chr6:33764158 A/G cg00334056 chr6:33755658 LEMD2 -0.29 -4.56 -0.38 1.22e-5 Schizophrenia; TGCT cis rs28595532 0.920 rs115472708 chr4:119773407 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs9790314 1.000 rs7653233 chr3:160992033 G/A cg03342759 chr3:160939853 NMD3 -0.43 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs12579753 0.719 rs4418885 chr12:82275845 A/T cg07988820 chr12:82153109 PPFIA2 -0.42 -4.44 -0.37 1.93e-5 Resting heart rate; TGCT cis rs1044826 0.642 rs6784684 chr3:139177634 T/C cg00490450 chr3:139108681 COPB2 0.52 4.53 0.38 1.39e-5 Obesity-related traits; TGCT cis rs4273100 0.646 rs11652784 chr17:19217261 C/T cg01534423 chr17:18965556 NA -0.78 -7.04 -0.53 1.16e-10 Schizophrenia; TGCT cis rs2549003 1.000 rs2070724 chr5:131822072 A/G cg00255919 chr5:131827918 IRF1 0.2 4.65 0.39 8.22e-6 Asthma (sex interaction); TGCT cis rs9297145 0.565 rs6952161 chr7:98733337 A/G cg05967295 chr7:98741636 SMURF1 0.68 8.83 0.62 8.5e-15 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs453301 0.653 rs2956244 chr8:8885166 A/G cg15556689 chr8:8085844 FLJ10661 0.82 7.24 0.55 4.15e-11 Joint mobility (Beighton score); TGCT cis rs2576037 0.523 rs1539881 chr18:44477897 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.57 -0.38 1.18e-5 Personality dimensions; TGCT cis rs4689388 0.890 rs11732208 chr4:6292716 G/C cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3947 1.000 rs1736081 chr8:11702840 T/G cg02840367 chr8:11660030 FDFT1 0.91 6.7 0.52 6.58e-10 Blood protein levels; TGCT cis rs9399137 0.507 rs12663810 chr6:135289782 G/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs12477438 0.748 rs4851185 chr2:99666497 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs3096299 0.967 rs2911256 chr16:89485096 G/C cg02187348 chr16:89574699 SPG7 0.48 4.66 0.39 7.91e-6 Multiple myeloma (IgH translocation); TGCT cis rs7681423 1.000 rs12644950 chr4:155537321 G/A cg20735720 chr4:155535218 FGG -0.46 -6.71 -0.52 6.24e-10 Fibrinogen; TGCT cis rs9926296 0.605 rs7205053 chr16:89856763 G/C cg27121462 chr16:89883253 FANCA 0.82 9.11 0.63 1.78e-15 Vitiligo; TGCT cis rs1784581 1.000 rs1784582 chr6:162400712 A/G cg17173639 chr6:162384350 PARK2 -0.5 -9.17 -0.64 1.26e-15 Itch intensity from mosquito bite; TGCT cis rs9902453 0.967 rs4294864 chr17:28440138 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.67 0.51 7.74e-10 Coffee consumption (cups per day); TGCT cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg13770153 chr20:60521292 NA -0.6 -7.83 -0.58 1.86e-12 Body mass index; TGCT cis rs17331151 0.505 rs71299610 chr3:52641703 T/G cg24616795 chr3:53032891 SFMBT1 0.58 4.85 0.4 3.59e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3862260 0.509 rs7552885 chr1:120164966 C/T cg16322792 chr1:120165303 ZNF697 0.35 8.4 0.6 8.92e-14 Systemic lupus erythematosus; TGCT cis rs9733 0.570 rs951281 chr1:150691122 A/C cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs10504229 0.871 rs10504226 chr8:58159283 A/G cg08280861 chr8:58055591 NA 0.36 4.77 0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg25036284 chr2:26402008 FAM59B -0.62 -5.06 -0.41 1.47e-6 Gut microbiome composition (summer); TGCT cis rs3733585 0.699 rs6449172 chr4:9966036 A/T cg11266682 chr4:10021025 SLC2A9 -0.59 -7.87 -0.58 1.53e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6790105 1 rs6790105 chr3:49393409 C/T cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.6 -0.38 1.02e-5 Childhood ear infection; TGCT cis rs11792861 0.926 rs12683988 chr9:111867290 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.48 0.37 1.66e-5 Menarche (age at onset); TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs3026101 0.624 rs1806219 chr17:5288073 A/G cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.63 0.38 9.15e-6 Body mass index; TGCT cis rs7954584 0.567 rs11612028 chr12:122387872 C/G cg21016266 chr12:122356598 WDR66 0.53 6.58 0.51 1.19e-9 Mean corpuscular volume; TGCT cis rs4234284 0.556 rs9968173 chr3:126965437 G/A cg25436886 chr3:127056972 NA -0.5 -4.9 -0.4 2.91e-6 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs77861329 1.000 rs6781635 chr3:52125343 A/G cg08692210 chr3:52188851 WDR51A 0.86 4.46 0.37 1.79e-5 Macrophage inflammatory protein 1b levels; TGCT cis rs7394190 0.748 rs60632610 chr10:75415677 C/T cg07699608 chr10:75541558 CHCHD1 0.59 4.46 0.37 1.85e-5 Incident atrial fibrillation; TGCT cis rs453301 0.686 rs7017868 chr8:8873293 G/A cg06636001 chr8:8085503 FLJ10661 -0.68 -5.63 -0.45 1.13e-7 Joint mobility (Beighton score); TGCT cis rs12497850 0.931 rs6791542 chr3:48787219 A/G cg05785598 chr3:49045655 WDR6 0.34 4.59 0.38 1.08e-5 Parkinson's disease; TGCT cis rs11031096 0.502 rs1442726 chr11:4094748 G/C cg18678763 chr11:4115507 RRM1 -0.47 -5.64 -0.45 1.09e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs112790992 1 rs112790992 chr14:105758217 A/C cg10792982 chr14:105748885 BRF1 0.22 4.53 0.38 1.39e-5 Platelet count; TGCT cis rs896854 0.654 rs896847 chr8:95972551 G/A cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.57e-9 Type 2 diabetes; TGCT cis rs1150668 0.835 rs1233696 chr6:28143010 T/C cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.69 -0.39 7.07e-6 Pubertal anthropometrics; TGCT cis rs3820928 0.904 rs1835159 chr2:227764057 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.67 -0.39 7.79e-6 Pulmonary function; TGCT cis rs3733585 0.699 rs4588456 chr4:9963895 A/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs250677 0.916 rs17109279 chr5:148416581 A/G cg23229984 chr5:148520753 ABLIM3 0.21 4.81 0.4 4.35e-6 Breast cancer; TGCT cis rs875971 1.000 rs2036264 chr7:65799904 G/A cg18876405 chr7:65276391 NA -0.32 -4.93 -0.4 2.63e-6 Aortic root size; TGCT cis rs10992471 0.528 rs4744135 chr9:95251874 A/C cg13798575 chr9:95087839 CENPP;NOL8 0.52 4.84 0.4 3.81e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9467773 1.000 rs1321479 chr6:26501897 C/T cg05738196 chr6:26577821 NA -0.87 -12.81 -0.75 1.87e-24 Intelligence (multi-trait analysis); TGCT cis rs2075165 0.901 rs1804999 chr1:156219450 A/G cg16558208 chr1:156270281 VHLL 0.26 4.5 0.37 1.52e-5 Tonsillectomy; TGCT cis rs524281 0.861 rs7941431 chr11:65960157 C/T cg00563793 chr11:65837595 PACS1 0.6 4.92 0.4 2.72e-6 Electroencephalogram traits; TGCT cis rs10791323 0.572 rs4412766 chr11:133742811 A/C cg03690763 chr11:133734501 NA -0.29 -4.89 -0.4 3.02e-6 Childhood ear infection; TGCT cis rs903263 0.965 rs12057561 chr1:84584894 C/T cg09664975 chr1:84543551 PRKACB 0.49 4.55 0.38 1.25e-5 Breast cancer (male); TGCT cis rs4746818 0.892 rs12437 chr10:70864065 T/C cg04149295 chr10:70884716 VPS26A 0.72 4.63 0.38 9.03e-6 Left atrial antero-posterior diameter; TGCT cis rs908922 0.676 rs4845784 chr1:152494583 G/C cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.25e-9 Hair morphology; TGCT cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg02458000 chr6:26745757 NA 0.52 4.86 0.4 3.41e-6 Intelligence (multi-trait analysis); TGCT cis rs11711311 0.955 rs9813630 chr3:113377361 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.8 -7.23 -0.54 4.28e-11 IgG glycosylation; TGCT cis rs28595532 0.841 rs55823625 chr4:119780600 T/A cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs12765878 0.692 rs10883926 chr10:105608838 G/A cg11005552 chr10:105648138 OBFC1 0.44 7.07 0.54 9.91e-11 Coronary artery disease; TGCT cis rs986417 0.818 rs1998189 chr14:60974987 A/T cg27398547 chr14:60952738 C14orf39 1.41 9.11 0.63 1.75e-15 Gut microbiota (bacterial taxa); TGCT cis rs9911578 1.000 rs654778 chr17:56736473 A/C cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs950776 0.506 rs12915366 chr15:78831753 G/A cg06917634 chr15:78832804 PSMA4 0.95 9.33 0.64 5.42e-16 Sudden cardiac arrest; TGCT cis rs72615157 0.664 rs6953580 chr7:99825275 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.6 -4.99 -0.41 1.97e-6 Lung function (FEV1/FVC); TGCT cis rs7843479 0.828 rs4357289 chr8:21777476 G/A cg17168535 chr8:21777572 XPO7 0.62 5.57 0.45 1.53e-7 Mean corpuscular volume; TGCT cis rs12048904 0.647 rs7528268 chr1:101329295 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.68 5.67 0.45 9.44e-8 Multiple sclerosis; TGCT cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs13191362 0.507 rs2849520 chr6:163132038 T/C cg06582575 chr6:163149167 PACRG;PARK2 -0.61 -5.73 -0.46 7.28e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7296418 0.961 rs1790122 chr12:123606739 G/A cg00376283 chr12:123451042 ABCB9 0.83 7.54 0.56 8.67e-12 Platelet count; TGCT cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9427116 0.677 rs9426831 chr1:154609657 A/T cg17218026 chr1:154582156 ADAR -0.28 -7.02 -0.53 1.3e-10 Blood protein levels; TGCT cis rs4665809 0.887 rs4665825 chr2:26333100 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs1483890 0.723 rs6807930 chr3:69411662 C/T cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs1395 0.778 rs2580761 chr2:27426362 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.66 9.16 0.64 1.39e-15 Blood metabolite levels; TGCT cis rs3011225 0.683 rs4660753 chr1:44321044 G/A cg12908607 chr1:44402522 ARTN -0.64 -7.74 -0.57 3e-12 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs12188164 0.965 rs41282625 chr5:475626 C/G cg22025206 chr5:502436 SLC9A3 -0.25 -4.47 -0.37 1.75e-5 Cystic fibrosis severity; TGCT cis rs9473924 0.542 rs9473939 chr6:50877477 T/G cg14470998 chr6:50812995 TFAP2B 1.35 8.21 0.59 2.48e-13 Body mass index; TGCT cis rs597539 0.616 rs513476 chr11:68698996 C/T cg21862992 chr11:68658383 NA 0.44 6.07 0.48 1.42e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs10203711 1.000 rs2334022 chr2:239565612 T/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.64 -0.51 8.76e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9549367 0.789 rs3861720 chr13:113906097 A/G cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs7666738 0.830 rs1426667 chr4:98949772 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs4824093 0.544 rs73443957 chr22:50305515 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -0.96 -5.38 -0.44 3.5e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10540 1.000 rs61876342 chr11:496193 T/G cg03934478 chr11:495069 RNH1 0.36 5.84 0.46 4.36e-8 Body mass index; TGCT cis rs427394 0.582 rs274661 chr5:6704848 C/T cg10857441 chr5:6722123 POLS -0.29 -6.21 -0.49 7.15e-9 Menopause (age at onset); TGCT cis rs7000551 0.689 rs6996872 chr8:22316753 T/C cg12081754 chr8:22256438 SLC39A14 0.28 4.53 0.38 1.38e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs13424612 0.965 rs4149541 chr2:240957734 G/A cg26363272 chr2:240904871 NDUFA10 0.28 4.83 0.4 4.01e-6 Odorant perception (isobutyraldehyde); TGCT cis rs62244186 0.606 rs6798590 chr3:44556861 T/A cg04389838 chr3:44770851 ZNF501 -0.39 -4.88 -0.4 3.23e-6 Depressive symptoms; TGCT cis rs9291683 0.632 rs11734375 chr4:10046298 A/G cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.29e-14 Bone mineral density; TGCT cis rs1357245 0.534 rs6766181 chr3:27100290 A/G cg03895047 chr3:27114861 NA -0.3 -4.52 -0.38 1.41e-5 Breast cancer; TGCT cis rs9457247 0.902 rs34560498 chr6:167395862 A/G cg23791538 chr6:167370224 RNASET2 -0.5 -4.9 -0.4 2.88e-6 Crohn's disease; TGCT cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7582180 0.627 rs4149517 chr2:101014247 C/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.19 -0.42 8.38e-7 Intelligence (multi-trait analysis); TGCT cis rs11792861 0.962 rs72607162 chr9:111793719 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.51 0.38 1.48e-5 Menarche (age at onset); TGCT cis rs910316 0.726 rs61979167 chr14:75663610 C/T cg08847533 chr14:75593920 NEK9 -0.84 -8.19 -0.59 2.75e-13 Height; TGCT cis rs7584330 0.737 rs1497128 chr2:238369211 A/G cg08992911 chr2:238395768 MLPH 0.56 4.6 0.38 1.04e-5 Prostate cancer; TGCT cis rs9303401 0.614 rs68100606 chr17:56500898 G/A cg25039879 chr17:56429692 SUPT4H1 0.5 4.55 0.38 1.27e-5 Cognitive test performance; TGCT cis rs2050392 0.861 rs1042058 chr10:30728101 T/C cg13289132 chr10:30722225 MAP3K8 -0.42 -5.05 -0.41 1.57e-6 Inflammatory bowel disease; TGCT cis rs9644630 0.672 rs4486225 chr8:19313404 A/G cg06699216 chr8:19333253 CSGALNACT1 -0.27 -4.79 -0.4 4.69e-6 Oropharynx cancer; TGCT cis rs9419702 0.568 rs11156445 chr10:133542301 T/C cg20568497 chr10:133558893 NA 0.44 4.84 0.4 3.84e-6 Survival in rectal cancer; TGCT cis rs1670533 1.000 rs633556 chr4:1092405 A/G cg20518497 chr4:1046821 NA -0.28 -4.58 -0.38 1.13e-5 Recombination rate (females); TGCT cis rs3780378 1.000 rs7847294 chr9:5097281 A/C cg02405213 chr9:5042618 JAK2 -0.63 -7.67 -0.57 4.47e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs3820928 0.904 rs10188570 chr2:227792540 G/A cg11843606 chr2:227700838 RHBDD1 -0.55 -5.0 -0.41 1.93e-6 Pulmonary function; TGCT cis rs986417 1.000 rs6573320 chr14:61092022 A/G cg27398547 chr14:60952738 C14orf39 1.36 7.38 0.55 1.96e-11 Gut microbiota (bacterial taxa); TGCT trans rs1814175 0.817 rs1319547 chr11:49916705 C/T cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs9611565 0.559 rs13056262 chr22:42081921 A/G cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Vitiligo; TGCT cis rs7829975 0.535 rs17683510 chr8:8500724 A/G cg06636001 chr8:8085503 FLJ10661 0.48 4.45 0.37 1.9e-5 Mood instability; TGCT cis rs10504229 0.593 rs16921626 chr8:58040359 C/T cg11062466 chr8:58055876 NA 0.34 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs9902453 0.967 rs12449783 chr17:28527653 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.56 0.51 1.32e-9 Coffee consumption (cups per day); TGCT cis rs2730245 0.550 rs2657364 chr7:158683825 T/C cg24397884 chr7:158709396 WDR60 0.37 4.93 0.4 2.63e-6 Height; TGCT cis rs4851254 0.961 rs7596385 chr2:100796598 A/T cg23118464 chr2:100721844 AFF3 0.58 4.46 0.37 1.84e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs981844 0.712 rs1037649 chr4:154737796 G/A cg14289246 chr4:154710475 SFRP2 -1.0 -9.32 -0.64 5.46e-16 Response to statins (LDL cholesterol change); TGCT cis rs854765 0.604 rs12948749 chr17:17949802 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.77 -7.91 -0.58 1.24e-12 Total body bone mineral density; TGCT cis rs4919694 1.000 rs12258551 chr10:104767892 C/G cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg06634786 chr22:41940651 POLR3H -0.86 -8.32 -0.6 1.34e-13 Vitiligo; TGCT cis rs2710642 0.815 rs6545971 chr2:63074986 A/T cg17519650 chr2:63277830 OTX1 0.62 5.54 0.45 1.72e-7 LDL cholesterol levels;LDL cholesterol; TGCT cis rs4776059 1.000 rs4776058 chr15:52880263 A/G cg25063058 chr15:52860530 ARPP19 0.53 4.72 0.39 6.28e-6 Schizophrenia; TGCT cis rs9911578 1.000 rs1267545 chr17:56646909 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs8141529 0.719 rs2097461 chr22:29191879 T/C cg02153584 chr22:29168773 CCDC117 0.71 6.08 0.48 1.41e-8 Lymphocyte counts; TGCT cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg11301795 chr4:187892539 NA -0.3 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs8051431 0.840 rs8050981 chr16:72014470 T/C cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs2120019 0.938 rs2120020 chr15:75316845 T/C cg17294928 chr15:75287854 SCAMP5 -0.79 -6.27 -0.49 5.46e-9 Blood trace element (Zn levels); TGCT cis rs868036 0.718 rs28675295 chr15:68116400 C/A cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs7611238 0.583 rs6778652 chr3:195147883 G/A cg27323046 chr3:195102265 ACAP2 0.39 5.14 0.42 1.05e-6 Body mass index; TGCT cis rs9583531 0.657 rs7337126 chr13:111376788 A/G cg24331049 chr13:111365604 ING1 0.9 8.96 0.63 4.09e-15 Coronary artery disease; TGCT cis rs6430585 0.527 rs2289959 chr2:136423904 C/T cg07169764 chr2:136633963 MCM6 0.93 8.19 0.59 2.71e-13 Corneal structure; TGCT cis rs860554 0.529 rs861272 chr1:201269122 A/C cg01022117 chr1:201258280 PKP1 0.3 4.44 0.37 1.96e-5 Panic disorder; TGCT cis rs12136530 0.774 rs2014772 chr1:19781247 C/T cg18923740 chr1:19971790 NBL1 0.39 4.78 0.39 4.86e-6 Lead levels in blood; TGCT cis rs655029 0.883 rs662451 chr2:31464974 C/T cg14018959 chr2:31480232 EHD3 -0.32 -4.45 -0.37 1.9e-5 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs9926296 0.546 rs6500442 chr16:89828862 T/C cg03388025 chr16:89894329 SPIRE2 0.47 8.08 0.59 4.81e-13 Vitiligo; TGCT cis rs16958440 0.867 rs75808931 chr18:44693042 C/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs4654899 0.733 rs10799677 chr1:21318456 A/C cg01072550 chr1:21505969 NA -0.53 -8.46 -0.6 6.37e-14 Superior frontal gyrus grey matter volume; TGCT cis rs9393692 0.902 rs6456711 chr6:26302572 A/C cg13736514 chr6:26305472 NA -0.43 -6.34 -0.49 3.98e-9 Educational attainment; TGCT cis rs7698623 0.850 rs6532025 chr4:88777194 A/G cg02735620 chr4:88950514 PKD2 -0.41 -4.56 -0.38 1.23e-5 Cardiovascular disease risk factors; TGCT cis rs7829975 0.711 rs12682352 chr8:8646246 A/G cg08975724 chr8:8085496 FLJ10661 0.57 5.19 0.42 8.32e-7 Mood instability; TGCT cis rs6484504 0.532 rs11031332 chr11:31278962 T/C cg14844989 chr11:31128820 NA -0.25 -4.89 -0.4 3e-6 Red blood cell count; TGCT cis rs6542838 0.641 rs4850890 chr2:99535426 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.59 -5.57 -0.45 1.49e-7 Fear of minor pain; TGCT cis rs1912483 0.505 rs11079772 chr17:45393739 A/C cg25173405 chr17:45401733 C17orf57 0.41 4.62 0.38 9.35e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs13148324 chr4:98833616 G/A cg18180107 chr4:99064573 C4orf37 0.56 5.18 0.42 8.78e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.790 rs9399571 chr6:146282061 A/G cg05347473 chr6:146136440 FBXO30 -0.54 -5.22 -0.42 7.38e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs61931739 0.500 rs7313094 chr12:34457508 T/C cg06521331 chr12:34319734 NA -0.28 -4.53 -0.38 1.38e-5 Morning vs. evening chronotype; TGCT cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg15691649 chr6:25882328 NA -0.35 -4.62 -0.38 9.55e-6 Blood metabolite levels; TGCT cis rs3771570 0.901 rs35256094 chr2:242439938 A/C cg21155796 chr2:242212141 HDLBP 0.92 6.63 0.51 9.25e-10 Prostate cancer; TGCT cis rs6964587 0.934 rs4512319 chr7:91733829 G/A cg17063962 chr7:91808500 NA 0.83 8.55 0.61 3.75e-14 Breast cancer; TGCT cis rs3540 0.960 rs60825716 chr15:90958053 G/A cg22089800 chr15:90895588 ZNF774 0.76 7.29 0.55 3.22e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2243480 0.803 rs403089 chr7:65517723 T/C cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs1878931 0.582 rs10048083 chr16:3417465 A/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 6.34 0.49 3.87e-9 Body mass index (adult); TGCT cis rs9733 0.596 rs12085275 chr1:150650265 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs9814567 0.686 rs1404289 chr3:134358109 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.71 6.28 0.49 5.22e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs35146811 0.700 rs7788301 chr7:99782753 C/G cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs12579753 0.917 rs7306043 chr12:82191282 G/A cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs4319547 0.695 rs6489002 chr12:122929822 T/C cg05707623 chr12:122985044 ZCCHC8 -0.71 -5.49 -0.44 2.16e-7 Body mass index; TGCT cis rs1075232 1.000 rs66581165 chr15:31743767 A/G cg01030201 chr15:31746330 NA -1.03 -5.61 -0.45 1.27e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs28735056 0.904 rs62103174 chr18:77621048 A/G cg20368463 chr18:77673604 PQLC1 0.39 4.76 0.39 5.21e-6 Schizophrenia; TGCT trans rs11662586 0.517 rs11662894 chr18:77713591 G/A cg05926928 chr17:57297772 GDPD1 0.76 7.2 0.54 5.06e-11 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs77106637 0.789 rs76550717 chr11:72428172 A/G cg03713592 chr11:72463424 ARAP1 1.1 8.29 0.6 1.56e-13 Type 2 diabetes; TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs3862435 0.518 rs2589960 chr15:90916387 A/G cg14166756 chr15:90894880 ZNF774 -0.32 -5.07 -0.41 1.4e-6 Response to exercise (triglyceride level interaction); TGCT cis rs875971 0.638 rs6960778 chr7:66071597 C/T cg18876405 chr7:65276391 NA -0.37 -5.57 -0.45 1.48e-7 Aortic root size; TGCT cis rs9435341 0.930 rs12408634 chr1:107579540 G/A cg09367891 chr1:107599246 PRMT6 0.64 5.71 0.46 7.78e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs1552244 0.554 rs59465469 chr3:9990800 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.3 -4.56 -0.38 1.21e-5 Alzheimer's disease; TGCT cis rs7666738 0.830 rs4443295 chr4:99044935 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10791097 0.629 rs11222361 chr11:130731424 T/G cg14779329 chr11:130786720 SNX19 0.27 4.89 0.4 3.11e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7918232 0.505 rs788221 chr10:27442247 G/C cg14442939 chr10:27389572 ANKRD26 -0.87 -5.69 -0.45 8.7e-8 Breast cancer; TGCT cis rs74417235 0.673 rs6873342 chr5:154051835 A/G cg08754654 chr5:154026448 NA -0.49 -4.65 -0.39 8.39e-6 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs4566357 0.615 rs10198214 chr2:227913314 A/C cg11843606 chr2:227700838 RHBDD1 -0.54 -5.25 -0.43 6.53e-7 Coronary artery disease; TGCT cis rs765787 0.530 rs3759893 chr15:45542950 G/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs9611565 0.546 rs5758431 chr22:42109917 A/G cg03806693 chr22:41940476 POLR3H 1.06 11.92 0.73 2.7e-22 Vitiligo; TGCT cis rs6570726 0.846 rs973856 chr6:145781916 C/T cg23711669 chr6:146136114 FBXO30 -0.72 -6.96 -0.53 1.78e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg19263069 chr19:5846552 FUT3 0.33 6.78 0.52 4.26e-10 Phosphorus levels; TGCT cis rs497273 0.534 rs13746 chr12:121201167 C/T cg02419362 chr12:121203948 SPPL3 0.19 4.52 0.38 1.43e-5 Systemic lupus erythematosus; TGCT cis rs6964587 0.967 rs10279210 chr7:91616891 G/A cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs3749237 0.555 rs7637665 chr3:49552295 T/C cg07636037 chr3:49044803 WDR6 0.62 5.83 0.46 4.59e-8 Resting heart rate; TGCT cis rs3733585 0.781 rs6449183 chr4:9970691 C/A cg11266682 chr4:10021025 SLC2A9 -0.62 -8.54 -0.61 4.06e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6542838 0.673 rs1949424 chr2:99468341 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.51 4.97 0.41 2.19e-6 Fear of minor pain; TGCT cis rs763121 0.719 rs138699 chr22:39129708 G/A cg06022373 chr22:39101656 GTPBP1 0.7 5.95 0.47 2.61e-8 Menopause (age at onset); TGCT trans rs916888 0.821 rs199506 chr17:44859031 A/G cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11030122 0.547 rs750525 chr11:3948894 G/A cg18678763 chr11:4115507 RRM1 -0.39 -4.76 -0.39 5.24e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs9303542 0.592 rs34378400 chr17:46589265 A/G cg25032089 chr17:46643351 HOXB3 0.57 5.74 0.46 6.78e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg00786635 chr1:25594202 NA 0.54 5.72 0.46 7.45e-8 Erythrocyte sedimentation rate; TGCT cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg10802521 chr3:52805072 NEK4 -0.7 -8.58 -0.61 3.21e-14 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.673 rs73263755 chr17:29198972 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10197940 0.624 rs6731486 chr2:152410732 C/T cg19508488 chr2:152266495 RIF1 -0.69 -6.39 -0.5 3.01e-9 Lung cancer; TGCT cis rs4713118 0.699 rs573179 chr6:27849676 C/A cg18675097 chr6:28227127 NKAPL -0.35 -4.47 -0.37 1.72e-5 Parkinson's disease; TGCT cis rs78487399 0.908 rs17031079 chr2:43804933 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs72700829 0.518 rs72694990 chr1:150223780 G/A cg03889479 chr1:149224237 NA -0.74 -4.62 -0.38 9.63e-6 Schizophrenia; TGCT cis rs7666738 0.546 rs10010088 chr4:98655945 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.29 0.43 5.45e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs986417 0.892 rs8016349 chr14:60798366 A/G cg27398547 chr14:60952738 C14orf39 -1.55 -6.87 -0.53 2.7e-10 Gut microbiota (bacterial taxa); TGCT cis rs7223966 1.000 rs72848797 chr17:61934664 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg23758822 chr17:41437982 NA 0.71 6.8 0.52 3.85e-10 Menopause (age at onset); TGCT cis rs1129187 0.702 rs2395943 chr6:42940673 A/G cg27588902 chr6:42928151 GNMT -0.57 -6.87 -0.53 2.76e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12477438 0.798 rs7606635 chr2:99644782 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT trans rs916888 0.821 rs199514 chr17:44856881 G/A cg01341218 chr17:43662625 NA -1.11 -9.41 -0.65 3.31e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17331151 0.573 rs3755801 chr3:52865798 G/A cg15956490 chr3:53032818 SFMBT1 0.45 5.63 0.45 1.13e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs651907 0.514 rs12636047 chr3:101434449 T/C cg12386194 chr3:101231763 SENP7 0.51 4.9 0.4 2.89e-6 Colorectal cancer; TGCT cis rs8013055 0.846 rs35723046 chr14:105970548 C/T cg25008857 chr14:105974488 NA 0.27 4.5 0.37 1.57e-5 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9911578 1.000 rs1494977 chr17:56863064 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs617219 0.726 rs72764969 chr5:78451409 A/G cg09550809 chr5:78407562 BHMT 0.41 5.67 0.45 9.4e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7659604 0.539 rs7686200 chr4:122764553 C/T cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.3 -0.43 5.06e-7 Type 2 diabetes; TGCT cis rs13256369 1.000 rs12550458 chr8:8567832 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs5750830 0.546 rs4821891 chr22:39785381 C/T cg11247378 chr22:39784982 NA -0.76 -10.44 -0.68 1.07e-18 Intelligence (multi-trait analysis); TGCT cis rs6540559 0.546 rs7551944 chr1:210029430 G/C cg21951975 chr1:209979733 IRF6 0.69 5.22 0.42 7.37e-7 Cleft lip with or without cleft palate; TGCT cis rs7010267 0.935 rs6469788 chr8:119952750 A/C cg17171407 chr8:119960777 TNFRSF11B 0.33 6.2 0.49 7.72e-9 Total body bone mineral density (age 45-60); TGCT cis rs7584330 0.518 rs7561919 chr2:238435241 A/G cg14458575 chr2:238380390 NA 0.45 4.82 0.4 4.04e-6 Prostate cancer; TGCT cis rs6089829 0.962 rs3899032 chr20:61658542 G/A cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs11969893 0.850 rs9485417 chr6:101300038 C/T cg12253828 chr6:101329408 ASCC3 -1.36 -6.32 -0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs11785400 0.793 rs9297969 chr8:143723237 A/G cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg00343986 chr7:65444356 GUSB 0.26 5.96 0.47 2.4e-8 Calcium levels; TGCT cis rs826838 1.000 rs6582619 chr12:38729904 A/G cg26384229 chr12:38710491 ALG10B 1.08 10.88 0.7 9.18e-20 Heart rate; TGCT cis rs1372520 0.873 rs2737026 chr4:90779823 A/G cg14346243 chr4:90757452 SNCA -0.63 -5.28 -0.43 5.7e-7 Neuroticism; TGCT cis rs1005277 0.565 rs2474565 chr10:38380828 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -7.9 -0.58 1.31e-12 Extrinsic epigenetic age acceleration; TGCT cis rs28595532 0.920 rs10018977 chr4:119785229 C/T cg00700008 chr4:120138107 USP53 0.49 4.48 0.37 1.71e-5 Cannabis dependence symptom count; TGCT cis rs2996428 0.667 rs11578070 chr1:3769871 G/C cg13057898 chr1:3703894 LRRC47 0.21 4.64 0.38 8.81e-6 Red cell distribution width; TGCT cis rs3820928 0.605 rs6748311 chr2:227792530 T/A cg11843606 chr2:227700838 RHBDD1 -0.51 -4.84 -0.4 3.86e-6 Pulmonary function; TGCT cis rs2204008 0.712 rs12371182 chr12:38321143 A/C cg26384229 chr12:38710491 ALG10B 0.83 7.22 0.54 4.62e-11 Bladder cancer; TGCT cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs6693567 0.526 rs834239 chr1:150375458 C/A cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs7666738 0.830 rs1405767 chr4:98965295 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1348850 0.874 rs1348848 chr2:178358233 A/C cg22681709 chr2:178499509 PDE11A 0.35 4.62 0.38 9.55e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4654899 0.655 rs4654883 chr1:21213708 C/T cg01072550 chr1:21505969 NA 0.55 8.92 0.63 5.11e-15 Superior frontal gyrus grey matter volume; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg02953382 chr22:24373134 LOC391322 0.77 8.01 0.58 7.12e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6921919 0.551 rs13201753 chr6:28331128 A/C cg18815343 chr6:28367644 ZSCAN12 -0.57 -5.36 -0.43 3.96e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2847281 0.622 rs2847258 chr18:12775963 C/T cg23598886 chr18:12777645 NA 0.39 4.91 0.4 2.77e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg08280861 chr8:58055591 NA 0.39 4.64 0.38 8.72e-6 Developmental language disorder (linguistic errors); TGCT cis rs1863918 0.575 rs4701057 chr5:178571857 G/A cg08616760 chr5:178157801 ZNF354A 0.52 4.53 0.38 1.34e-5 Depression in response to interferon-based therapy in chronic hepatitis C; TGCT cis rs11264213 0.591 rs4653157 chr1:36543278 C/T cg27506609 chr1:36549197 TEKT2 -0.33 -4.88 -0.4 3.15e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs10005173 chr4:98816062 T/C cg05340658 chr4:99064831 C4orf37 0.51 6.03 0.48 1.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7726839 0.574 rs11739866 chr5:636299 C/T cg16624210 chr5:671434 TPPP 0.42 4.68 0.39 7.38e-6 Obesity-related traits; TGCT cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3734729 0.702 rs11155716 chr6:150575200 A/G cg16439130 chr6:149658548 MAP3K7IP2 0.4 4.79 0.39 4.75e-6 Pulmonary function;Pulmonary function (smoking interaction); TGCT cis rs17376456 0.825 rs10072232 chr5:93398890 G/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs2404602 0.669 rs1875884 chr15:76638161 C/T cg22467129 chr15:76604101 ETFA -0.57 -6.86 -0.52 2.88e-10 Blood metabolite levels; TGCT cis rs2933343 0.553 rs35076317 chr3:128715535 T/C cg11901034 chr3:128598214 ACAD9 -0.56 -5.2 -0.42 7.83e-7 IgG glycosylation; TGCT cis rs6570726 0.902 rs396681 chr6:145853603 T/C cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.34e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs137699 0.959 rs5757631 chr22:39755953 T/C cg24399712 chr22:39784796 NA -0.67 -5.99 -0.47 2.08e-8 IgG glycosylation; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg20007245 chr22:24372913 LOC391322 -0.7 -6.9 -0.53 2.38e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9638182 0.614 rs79624003 chr7:73012785 A/G cg14087351 chr7:73037990 MLXIPL -0.65 -5.07 -0.41 1.43e-6 Triglycerides; TGCT cis rs10262624 0.504 rs4722255 chr7:23746072 G/T cg09690326 chr7:23720549 C7orf46 -0.44 -4.72 -0.39 6.27e-6 Schizophrenia; TGCT cis rs6684514 1.000 rs67034206 chr1:156270260 C/T cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6582630 0.555 rs61932279 chr12:38349096 C/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg25767906 chr1:53392781 SCP2 0.5 5.85 0.46 4.15e-8 Monocyte count; TGCT cis rs2486288 0.656 rs1706768 chr15:45569443 T/C cg14582100 chr15:45693742 SPATA5L1 -0.42 -4.65 -0.39 8.49e-6 Glomerular filtration rate; TGCT cis rs11098499 0.954 rs12508504 chr4:120410607 A/C cg09307838 chr4:120376055 NA 0.68 6.56 0.51 1.31e-9 Corneal astigmatism; TGCT trans rs28735056 0.591 rs2277724 chr18:77694294 C/A cg05926928 chr17:57297772 GDPD1 -0.68 -6.82 -0.52 3.55e-10 Schizophrenia; TGCT cis rs6893807 1.000 rs2304608 chr5:87962298 C/A cg24804195 chr5:87968844 LOC645323 0.76 5.64 0.45 1.09e-7 Body mass index; TGCT cis rs11792861 0.591 rs2282206 chr9:111746267 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 7.43 0.56 1.54e-11 Menarche (age at onset); TGCT cis rs10883723 0.810 rs17782574 chr10:104279394 G/A cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg10295955 chr4:187884368 NA 0.93 13.76 0.78 9.85e-27 Lobe attachment (rater-scored or self-reported); TGCT cis rs3008870 0.755 rs3929738 chr1:67397865 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.29 0.6 1.59e-13 Lymphocyte percentage of white cells; TGCT cis rs3008870 0.755 rs4655660 chr1:67402953 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.29 0.6 1.59e-13 Lymphocyte percentage of white cells; TGCT cis rs13256369 1.000 rs12545771 chr8:8567977 C/G cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs4975709 0.569 rs4975742 chr5:1858612 T/C cg14773178 chr5:1868261 NA 0.34 5.49 0.44 2.14e-7 Cardiovascular disease risk factors; TGCT cis rs72781680 0.898 rs72788212 chr2:24087385 G/A cg08917208 chr2:24149416 ATAD2B 0.77 4.69 0.39 7.06e-6 Lymphocyte counts; TGCT cis rs6754311 0.773 rs309178 chr2:136611624 C/T cg07169764 chr2:136633963 MCM6 -0.62 -5.74 -0.46 7e-8 Mosquito bite size; TGCT cis rs66573146 0.831 rs6832482 chr4:7023433 A/T cg01220768 chr4:7056774 TADA2B 0.32 4.43 0.37 2.01e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs752092 1.000 rs7182945 chr15:101784223 C/T cg19997662 chr15:101784653 CHSY1 -0.31 -5.81 -0.46 4.9e-8 Corneal structure; TGCT cis rs2172802 0.693 rs4860097 chr4:62482723 A/G cg04118610 chr4:62707027 LPHN3 -0.44 -4.66 -0.39 8.18e-6 Partial epilepsies; TGCT cis rs35264875 0.898 rs72928701 chr11:68861564 C/T cg02660097 chr11:68866761 NA 0.32 4.61 0.38 9.94e-6 Blond vs. brown hair color; TGCT cis rs7552404 0.924 rs2275378 chr1:76198436 T/C cg10523679 chr1:76189770 ACADM 0.89 9.62 0.65 1.08e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg01017244 chr2:74357527 NA 0.5 8.09 0.59 4.6e-13 Gestational age at birth (maternal effect); TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg16325326 chr1:53192061 ZYG11B 0.6 6.97 0.53 1.68e-10 Monocyte count; TGCT cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.78 7.09 0.54 8.96e-11 Prudent dietary pattern; TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg27535305 chr1:53392650 SCP2 -0.29 -5.59 -0.45 1.4e-7 Monocyte count; TGCT cis rs1670533 1.000 rs10031302 chr4:1059664 G/A cg20887711 chr4:1340912 KIAA1530 0.65 5.14 0.42 1.05e-6 Recombination rate (females); TGCT cis rs6835174 0.730 rs28862337 chr4:5987097 C/T cg13644262 chr4:6449564 PPP2R2C -0.34 -4.74 -0.39 5.88e-6 Cannabis use (initiation); TGCT cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT trans rs4332037 0.539 rs11982455 chr7:1911458 A/C cg25206134 chr2:45395956 NA 1.01 7.99 0.58 7.9e-13 Bipolar disorder; TGCT cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg09904177 chr6:26538194 HMGN4 -0.68 -6.12 -0.48 1.11e-8 Intelligence (multi-trait analysis); TGCT cis rs7714584 1.000 rs7716903 chr5:150258574 C/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs10791097 0.967 rs1944142 chr11:130717440 C/T cg12179176 chr11:130786555 SNX19 0.65 6.88 0.53 2.6e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9394169 0.613 rs4713685 chr6:33774525 C/T cg00334056 chr6:33755658 LEMD2 0.25 4.6 0.38 1.04e-5 Essential tremor; TGCT cis rs1215050 0.740 rs783916 chr4:99026264 A/C cg05340658 chr4:99064831 C4orf37 -0.43 -5.28 -0.43 5.7e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs950027 0.620 rs1719245 chr15:45623782 T/C cg26924012 chr15:45694286 SPATA5L1 0.82 9.12 0.63 1.72e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs8051149 0.688 rs12444670 chr16:87870312 C/T cg01412419 chr16:87856264 NA 0.5 6.06 0.48 1.53e-8 Blood metabolite levels; TGCT cis rs6121246 0.529 rs6060359 chr20:30209740 A/G cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs6089584 0.546 rs6061980 chr20:60618877 G/A cg06108461 chr20:60628389 TAF4 -0.42 -5.27 -0.43 5.89e-7 Body mass index; TGCT cis rs11030122 0.673 rs10835508 chr11:4045360 A/T cg18678763 chr11:4115507 RRM1 -0.47 -5.79 -0.46 5.47e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs752010 0.631 rs4660549 chr1:42088102 A/G cg06885757 chr1:42089581 HIVEP3 0.32 6.0 0.47 1.97e-8 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs6987853 0.933 rs2356610 chr8:42446238 T/G cg20539142 chr8:42623718 CHRNA6 -0.2 -4.82 -0.4 4.2e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs903263 1.000 rs2037454 chr1:84645266 G/A cg09664975 chr1:84543551 PRKACB 0.48 4.6 0.38 1.01e-5 Breast cancer (male); TGCT cis rs4699052 0.928 rs4456958 chr4:104215332 A/G cg16532752 chr4:104119610 CENPE -0.56 -5.05 -0.41 1.57e-6 Testicular germ cell tumor; TGCT cis rs858239 0.614 rs10229956 chr7:23402936 C/G cg05602783 chr7:23145260 KLHL7 0.61 5.43 0.44 2.89e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg19729930 chr2:74357872 NA 0.62 9.05 0.63 2.44e-15 Gestational age at birth (maternal effect); TGCT cis rs4252435 0.520 rs7797908 chr7:142641207 T/C cg09833174 chr7:143059591 FAM131B -1.02 -4.65 -0.39 8.26e-6 Cancer; TGCT cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg05368731 chr17:41323189 NBR1 1.16 13.76 0.78 1.03e-26 Menopause (age at onset); TGCT cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.754 rs9497401 chr6:146051271 T/C cg13319975 chr6:146136371 FBXO30 0.56 5.0 0.41 1.9e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9644630 1.000 rs9644630 chr8:19370598 C/T cg01280390 chr8:19363452 CSGALNACT1 0.27 4.6 0.38 1.02e-5 Oropharynx cancer; TGCT trans rs7726839 0.540 rs12520279 chr5:657291 T/C cg11887960 chr12:57824829 NA 1.16 9.4 0.65 3.51e-16 Obesity-related traits; TGCT cis rs1018836 0.923 rs10956749 chr8:91621573 G/A cg16814680 chr8:91681699 NA -0.86 -9.19 -0.64 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs797680 0.586 rs2281525 chr1:93595306 G/C cg17826107 chr1:92977322 EVI5 -0.22 -4.61 -0.38 9.71e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2115630 0.936 rs8033459 chr15:85253258 C/T cg11189052 chr15:85197271 WDR73 -0.67 -6.57 -0.51 1.25e-9 P wave terminal force; TGCT cis rs637571 0.528 rs566266 chr11:65573587 A/C cg04055107 chr11:65626734 MUS81;CFL1 -0.67 -6.01 -0.48 1.9e-8 Eosinophil percentage of white cells; TGCT cis rs10504229 0.638 rs6981055 chr8:58113941 T/C cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs6665290 0.545 rs6426584 chr1:227374949 A/T cg10327440 chr1:227177885 CDC42BPA -0.57 -6.02 -0.48 1.83e-8 Myeloid white cell count; TGCT cis rs1215050 0.791 rs13107606 chr4:98823187 C/A cg17366294 chr4:99064904 C4orf37 0.56 6.05 0.48 1.57e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT cis rs4730250 0.707 rs61014091 chr7:106810107 A/C cg02696742 chr7:106810147 HBP1 -0.73 -5.98 -0.47 2.24e-8 Osteoarthritis; TGCT cis rs12477438 0.798 rs7570657 chr2:99654281 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs682748 0.810 rs6892968 chr5:17112350 A/T cg23987134 chr5:17158319 LOC285696 -0.21 -4.91 -0.4 2.78e-6 Hippocampal atrophy; TGCT cis rs617219 0.726 rs2364596 chr5:78434291 C/T cg09550809 chr5:78407562 BHMT 0.41 5.65 0.45 1.04e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7666738 0.830 rs7694889 chr4:98855596 T/C cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs765787 0.530 rs12910270 chr15:45512086 G/A cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT cis rs9322193 0.923 rs1080670 chr6:149941297 C/G cg13206674 chr6:150067644 NUP43 0.52 4.53 0.38 1.37e-5 Lung cancer; TGCT cis rs2458413 0.933 rs2669450 chr8:105371752 C/T cg23108931 chr8:105342351 NA 0.39 6.96 0.53 1.74e-10 Paget's disease; TGCT cis rs1552244 0.882 rs67631672 chr3:10004768 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.8 -0.52 3.93e-10 Alzheimer's disease; TGCT cis rs9914988 0.887 rs9895625 chr17:27108516 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs35883536 0.868 rs2484535 chr1:101107748 C/T cg06223162 chr1:101003688 GPR88 -0.29 -4.86 -0.4 3.53e-6 Monocyte count; TGCT cis rs7010267 0.712 rs4567065 chr8:120008274 C/A cg17171407 chr8:119960777 TNFRSF11B 0.27 5.0 0.41 1.9e-6 Total body bone mineral density (age 45-60); TGCT cis rs10791097 0.677 rs11222359 chr11:130730648 A/G cg12179176 chr11:130786555 SNX19 0.75 8.81 0.62 9.16e-15 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1059312 0.966 rs2291349 chr12:129284248 T/C cg09035930 chr12:129282057 SLC15A4 0.59 11.59 0.72 1.72e-21 Systemic lupus erythematosus; TGCT cis rs6558530 0.965 rs4372027 chr8:1707958 T/C cg09410841 chr8:1729607 CLN8 0.91 10.31 0.68 2.23e-18 Systolic blood pressure; TGCT cis rs8084125 0.832 rs62105174 chr18:74948324 G/A cg15443732 chr18:74961078 GALR1 0.48 4.7 0.39 6.75e-6 Obesity-related traits; TGCT cis rs77741769 0.571 rs73415720 chr12:121344515 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT trans rs4332037 0.539 rs868754 chr7:2033780 G/C cg10840412 chr1:235813424 GNG4 0.96 6.63 0.51 9.15e-10 Bipolar disorder; TGCT cis rs9682041 0.696 rs10936626 chr3:170095019 G/A cg11886554 chr3:170076028 SKIL 0.61 4.78 0.39 4.77e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.87 -9.35 -0.64 4.66e-16 Menarche (age at onset); TGCT cis rs78487399 0.808 rs114563746 chr2:43760880 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.78 4.78 0.39 4.9100000000000004e-06 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12477438 0.765 rs2167930 chr2:99592551 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs9300255 0.602 rs1716165 chr12:123648881 C/T cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs2239547 0.603 rs34230854 chr3:53078590 C/A cg10802521 chr3:52805072 NEK4 -0.57 -5.32 -0.43 4.62e-7 Schizophrenia; TGCT cis rs11969893 0.850 rs12664068 chr6:101362098 G/T cg12253828 chr6:101329408 ASCC3 1.25 4.88 0.4 3.17e-6 Economic and political preferences (immigration/crime); TGCT cis rs6840360 0.642 rs2724568 chr4:152352223 C/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs7659604 0.791 rs57316471 chr4:122663939 A/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.32 -5.29 -0.43 5.32e-7 Type 2 diabetes; TGCT cis rs2456568 0.867 rs2462744 chr11:93682913 G/A cg26875233 chr11:93583750 C11orf90 -0.45 -5.65 -0.45 1.04e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6088590 0.550 rs12624640 chr20:32952125 G/A cg06115741 chr20:33292138 TP53INP2 0.59 4.75 0.39 5.57e-6 Coronary artery disease; TGCT cis rs2576037 0.583 rs11660085 chr18:44529603 A/G cg23302884 chr18:44338147 ST8SIA5 0.41 4.7 0.39 6.81e-6 Personality dimensions; TGCT cis rs4851266 0.966 rs2309838 chr2:100838455 T/C cg07810366 chr2:100720526 AFF3 -0.37 -5.33 -0.43 4.53e-7 Educational attainment; TGCT cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs9830388 0.604 rs11916411 chr3:23567980 G/T cg25382821 chr3:23496403 UBE2E2 0.24 4.46 0.37 1.84e-5 RR interval (tricyclic/tetracyclic antidepressant use interaction); TGCT trans rs57221529 0.766 rs58015612 chr5:580665 A/T cg11887960 chr12:57824829 NA 1.06 9.28 0.64 6.78e-16 Lung disease severity in cystic fibrosis; TGCT cis rs939658 0.805 rs1915726 chr15:79420620 C/G cg17916960 chr15:79447300 NA -0.5 -7.7 -0.57 3.74e-12 Refractive error; TGCT cis rs274567 0.599 rs11242110 chr5:131743777 A/C cg24060327 chr5:131705240 SLC22A5 0.54 5.31 0.43 4.94e-7 Blood metabolite levels; TGCT trans rs1814175 0.630 rs1722019 chr11:49904102 G/A cg15704280 chr7:45808275 SEPT13 -0.59 -6.82 -0.52 3.49e-10 Height; TGCT trans rs629535 0.665 rs2433331 chr8:70041943 T/C cg21567404 chr3:27674614 NA 0.56 9.09 0.63 2.03e-15 Dupuytren's disease; TGCT cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.57e-9 Type 2 diabetes; TGCT cis rs12477438 0.765 rs28648058 chr2:99696417 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.61 -5.23 -0.43 6.94e-7 Chronic sinus infection; TGCT cis rs72945132 0.825 rs2298411 chr11:70206046 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs74417235 0.684 rs13179754 chr5:154059845 C/T cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs4851266 1.000 rs6750097 chr2:100836885 T/C cg07810366 chr2:100720526 AFF3 -0.37 -5.33 -0.43 4.53e-7 Educational attainment; TGCT cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg11502198 chr6:26597334 ABT1 0.55 4.89 0.4 3.05e-6 Intelligence (multi-trait analysis); TGCT cis rs7924176 0.643 rs1908339 chr10:75843100 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.55 5.09 0.42 1.28e-6 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs6728642 1.000 rs73959416 chr2:97604518 A/T cg26665480 chr2:98280029 ACTR1B -0.92 -5.56 -0.45 1.56e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs732765 0.689 rs10139925 chr14:75123076 C/T cg06637938 chr14:75390232 RPS6KL1 -0.56 -4.67 -0.39 7.7e-6 Non-small cell lung cancer; TGCT cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg13695892 chr22:41940480 POLR3H -0.77 -7.47 -0.56 1.24e-11 Vitiligo; TGCT cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2180341 1.000 rs6569483 chr6:127658855 G/A cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs6952808 0.609 rs10227517 chr7:1950292 A/T cg22963979 chr7:1858916 MAD1L1 -0.37 -5.58 -0.45 1.42e-7 Bipolar disorder and schizophrenia; TGCT cis rs36051895 0.659 rs7046077 chr9:5045328 C/G cg02405213 chr9:5042618 JAK2 -0.78 -10.85 -0.7 1.1e-19 Pediatric autoimmune diseases; TGCT cis rs7226408 0.948 rs2217110 chr18:34400782 T/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs35306767 0.714 rs12762955 chr10:1078782 A/C cg20503657 chr10:835505 NA 0.5 5.69 0.45 8.72e-8 Eosinophil percentage of granulocytes; TGCT cis rs6582630 0.555 rs1969362 chr12:38514843 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.74 0.57 3.09e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9303401 0.614 rs35245220 chr17:56510305 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.59 6.15 0.48 9.66e-9 Cognitive test performance; TGCT cis rs12497850 0.931 rs28642807 chr3:48926816 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg11965913 chr1:205819406 PM20D1 0.5 6.89 0.53 2.5e-10 Menarche (age at onset); TGCT cis rs2204008 0.623 rs1663281 chr12:38120936 A/G cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs6591182 0.504 rs7116712 chr11:65372518 A/G cg12758867 chr11:65354231 EHBP1L1 0.24 4.8 0.4 4.56e-6 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs9611565 0.644 rs2413652 chr22:42097238 C/T cg06634786 chr22:41940651 POLR3H 0.82 7.82 0.57 1.92e-12 Vitiligo; TGCT cis rs7552404 0.889 rs1250874 chr1:76190978 A/G cg22875332 chr1:76189707 ACADM 0.73 9.16 0.64 1.34e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs838147 0.537 rs632111 chr19:49208978 A/G cg05248581 chr19:49925731 PTH2 0.41 4.5 0.37 1.54e-5 Dietary macronutrient intake; TGCT cis rs35306767 0.903 rs61833260 chr10:975148 T/G cg20503657 chr10:835505 NA 0.69 9.6 0.65 1.15e-16 Eosinophil percentage of granulocytes; TGCT cis rs10504229 0.683 rs55986917 chr8:58137210 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs2242116 0.760 rs4682845 chr3:46955404 G/C cg02527881 chr3:46936655 PTH1R -0.3 -5.56 -0.45 1.58e-7 Birth weight; TGCT cis rs2439831 1.000 rs2254321 chr15:43707542 T/G cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.12 0.59 3.99e-13 Lung cancer in ever smokers; TGCT trans rs1814175 0.647 rs4881649 chr11:49845560 A/G cg15704280 chr7:45808275 SEPT13 -0.59 -6.76 -0.52 4.71e-10 Height; TGCT cis rs9814567 1.000 rs1357762 chr3:134264859 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -9.16 -0.64 1.36e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7681440 0.728 rs1812923 chr4:90739539 C/A cg26578617 chr4:90757533 SNCA -0.45 -4.58 -0.38 1.1e-5 Dementia with Lewy bodies; TGCT cis rs6460942 0.731 rs7799372 chr7:12233784 T/A cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs2130392 0.962 rs7660116 chr4:185626542 G/A cg14471096 chr4:185570637 CCDC111;CASP3 0.52 4.82 0.4 4.06e-6 Kawasaki disease; TGCT cis rs1163251 0.837 rs517533 chr1:120229170 T/G cg19096424 chr1:120255104 PHGDH 0.61 5.99 0.47 2.09e-8 Blood metabolite levels; TGCT cis rs2832191 0.755 rs2832192 chr21:30491173 G/T cg24692254 chr21:30365293 RNF160 -0.87 -9.28 -0.64 7.12e-16 Dental caries; TGCT trans rs12655019 0.920 rs79354983 chr5:56221537 A/G cg25190722 chr1:3801660 DFFB 0.67 7.44 0.56 1.48e-11 Breast cancer (early onset); TGCT cis rs7940866 0.903 rs11222421 chr11:130872351 A/T cg05962950 chr11:130786565 SNX19 0.67 6.47 0.5 2.06e-9 Schizophrenia; TGCT cis rs4665809 1.000 rs2053367 chr2:26293413 T/C cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs1023500 0.551 rs133379 chr22:42468535 A/G cg05082376 chr22:42548792 NA -0.23 -5.49 -0.44 2.18e-7 Schizophrenia; TGCT cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg12310025 chr6:25882481 NA -0.68 -6.01 -0.47 1.96e-8 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.716 rs12594577 chr15:76828793 A/C cg26408565 chr15:76604113 ETFA -0.4 -5.24 -0.43 6.54e-7 Blood metabolite levels; TGCT cis rs7917772 0.503 rs11191342 chr10:104344450 G/A cg05855489 chr10:104503620 C10orf26 -0.61 -5.41 -0.44 3.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs911555 0.511 rs2296483 chr14:104029792 G/A cg26031613 chr14:104095156 KLC1 0.52 4.82 0.4 4.14e-6 Intelligence (multi-trait analysis); TGCT cis rs6866344 0.697 rs62392823 chr5:178126968 T/C cg10224037 chr5:178157518 ZNF354A 0.94 7.97 0.58 8.92e-13 Neutrophil percentage of white cells; TGCT cis rs61990749 0.544 rs3759728 chr14:78230159 A/T cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs13191362 1.000 rs34344906 chr6:162993378 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.32 0.43 4.73e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1483890 0.605 rs6549209 chr3:69413028 A/C cg22125112 chr3:69402811 FRMD4B 0.28 4.68 0.39 7.47e-6 Resting heart rate; TGCT cis rs17601876 0.814 rs34784350 chr15:51559552 C/T cg19946085 chr15:51559439 CYP19A1 -0.33 -4.99 -0.41 2.01e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs13090388 1 rs13090388 chr3:49391082 C/T cg03060546 chr3:49711283 APEH -0.63 -5.47 -0.44 2.39e-7 Intelligence (multi-trait analysis);Educational attainment (years of education); TGCT cis rs3760982 0.585 rs67773424 chr19:44293994 G/A cg12072164 chr19:44306565 LYPD5 0.3 4.45 0.37 1.86e-5 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs9325144 0.555 rs7960411 chr12:38703019 A/G cg26384229 chr12:38710491 ALG10B -0.67 -6.17 -0.48 9.08e-9 Morning vs. evening chronotype; TGCT cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg17971929 chr21:40555470 PSMG1 -0.68 -6.21 -0.49 7.44e-9 Cognitive function; TGCT cis rs2067615 0.579 rs7486905 chr12:107160169 G/A cg15890332 chr12:107067104 RFX4 0.29 5.64 0.45 1.07e-7 Heart rate; TGCT cis rs931127 0.692 rs7934517 chr11:65445673 C/T cg17480646 chr11:65405466 SIPA1 -0.44 -5.8 -0.46 5.26e-8 Systemic lupus erythematosus; TGCT cis rs12477438 0.520 rs6741772 chr2:99738961 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.85 0.76 1.49e-24 Chronic sinus infection; TGCT cis rs1697139 0.583 rs11739727 chr5:66540940 G/A cg11553311 chr5:66541588 NA 0.27 5.83 0.46 4.47e-8 Breast cancer; TGCT cis rs6088590 0.582 rs6059909 chr20:33139691 C/A cg08999081 chr20:33150536 PIGU 0.28 5.41 0.44 3.11e-7 Coronary artery disease; TGCT cis rs1046896 0.519 rs9900369 chr17:80829807 G/A cg03160526 chr17:80928410 B3GNTL1 0.33 4.54 0.38 1.33e-5 Glycated hemoglobin levels; TGCT cis rs61990749 0.597 rs1477262 chr14:78226653 G/A cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs28595532 0.920 rs55901549 chr4:119770172 T/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs492146 0.756 rs374275 chr6:52840797 G/C cg06706454 chr6:52930286 FBXO9 -0.51 -4.64 -0.38 8.63e-6 Epilepsy (remission after treatment); TGCT cis rs7552404 0.924 rs1611823 chr1:76221706 T/G cg10523679 chr1:76189770 ACADM 0.82 8.79 0.62 1.05e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10791097 0.608 rs12363140 chr11:130744268 A/C cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12220898 0.749 rs7905866 chr10:50483552 T/C cg06072769 chr10:50146962 WDFY4 0.39 5.19 0.42 8.27e-7 Inflammatory biomarkers; TGCT cis rs12477438 0.765 rs6735801 chr2:99657995 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.61 -0.38 9.83e-6 Chronic sinus infection; TGCT cis rs10875746 0.951 rs2269935 chr12:48516464 G/T cg20731937 chr12:48336164 NA 0.62 4.9 0.4 2.99e-6 Longevity (90 years and older); TGCT cis rs9467603 1.000 rs6902211 chr6:25767437 G/A cg16898833 chr6:26189333 HIST1H4D -0.99 -4.75 -0.39 5.62e-6 Intelligence (multi-trait analysis); TGCT cis rs881375 0.692 rs2072438 chr9:123651301 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.4 0.44 3.34e-7 Rheumatoid arthritis; TGCT cis rs6939532 0.522 rs9379870 chr6:26374410 A/G cg05738196 chr6:26577821 NA -0.52 -5.02 -0.41 1.76e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs11722228 0.522 rs7662229 chr4:10133014 A/T cg26043149 chr18:55253948 FECH 1.23 14.06 0.78 1.97e-27 Gout;Urate levels;Serum uric acid levels; TGCT cis rs854765 0.583 rs7503334 chr17:17779458 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.98 -0.58 8.43e-13 Total body bone mineral density; TGCT cis rs7666738 0.830 rs7664305 chr4:99037691 G/A cg05340658 chr4:99064831 C4orf37 0.51 5.76 0.46 6.23e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs1119689 chr6:8460754 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs12477438 0.798 rs10196680 chr2:99628617 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs10504229 0.639 rs56825757 chr8:58106469 A/G cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg06238570 chr21:40685208 BRWD1 -0.81 -9.15 -0.64 1.4e-15 Cognitive function; TGCT cis rs981844 0.689 rs6835372 chr4:154682056 T/C cg14289246 chr4:154710475 SFRP2 -0.89 -8.12 -0.59 3.89e-13 Response to statins (LDL cholesterol change); TGCT cis rs12142240 0.698 rs7515598 chr1:46818479 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs3749237 0.595 rs1050088 chr3:49570882 C/T cg02487422 chr3:49467188 NICN1 -0.58 -5.92 -0.47 2.9e-8 Resting heart rate; TGCT cis rs1008375 0.863 rs4698632 chr4:17614894 T/C cg16339924 chr4:17578868 LAP3 0.64 5.17 0.42 9.1e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs916888 0.687 rs199456 chr17:44797919 C/T cg15921436 chr17:44337874 NA 0.58 8.1 0.59 4.33e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7267979 0.816 rs409853 chr20:25506067 T/C cg14121845 chr20:25566513 NINL 0.46 4.76 0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs644799 1.000 rs586498 chr11:95537828 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs40363 0.729 rs6501176 chr16:3522197 A/G cg00484396 chr16:3507460 NAT15 -0.33 -4.88 -0.4 3.18e-6 Tuberculosis; TGCT cis rs40363 0.620 rs1137454 chr16:3533577 C/G cg22508957 chr16:3507546 NAT15 -0.47 -5.33 -0.43 4.43e-7 Tuberculosis; TGCT cis rs4654899 0.802 rs10737452 chr1:21199764 C/T cg01072550 chr1:21505969 NA 0.46 7.19 0.54 5.32e-11 Superior frontal gyrus grey matter volume; TGCT cis rs6543140 0.964 rs918000 chr2:103067862 C/T cg09003973 chr2:102972529 NA 0.56 4.67 0.39 7.86e-6 Blood protein levels; TGCT cis rs13108904 0.539 rs13141169 chr4:1340353 C/T cg00684032 chr4:1343700 KIAA1530 0.23 4.97 0.41 2.18e-6 Obesity-related traits; TGCT cis rs12497850 0.931 rs3774628 chr3:48801840 C/T cg07636037 chr3:49044803 WDR6 0.95 10.82 0.7 1.29e-19 Parkinson's disease; TGCT cis rs35306767 0.903 rs35637113 chr10:874149 G/C cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg16423285 chr20:60520624 NA -0.63 -7.07 -0.54 1.01e-10 Body mass index; TGCT cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg19318889 chr4:1322082 MAEA 0.17 4.47 0.37 1.71e-5 Obesity-related traits; TGCT cis rs11690935 0.959 rs75922913 chr2:172620152 T/C cg13550731 chr2:172543902 DYNC1I2 -1.2 -12.28 -0.74 3.49e-23 Schizophrenia; TGCT cis rs4803468 0.934 rs2317131 chr19:41885151 C/T cg09537434 chr19:41945824 ATP5SL -0.85 -9.13 -0.63 1.57e-15 Height; TGCT cis rs7666738 0.830 rs35951881 chr4:98999474 A/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12620999 1.000 rs4558538 chr2:238055975 C/T cg23555395 chr2:238036564 NA -0.28 -4.72 -0.39 6.18e-6 Systemic lupus erythematosus; TGCT cis rs7786808 0.741 rs11765319 chr7:158226790 A/G cg01191920 chr7:158217561 PTPRN2 -0.4 -6.21 -0.49 7.21e-9 Obesity-related traits; TGCT cis rs950169 0.881 rs62029599 chr15:84956565 A/C cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs7959452 0.640 rs4274230 chr12:69700772 T/G cg11871910 chr12:69753446 YEATS4 0.63 6.37 0.5 3.34e-9 Blood protein levels; TGCT cis rs1153858 1.000 rs9788780 chr15:45685487 T/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs362296 0.698 rs3135172 chr4:3258735 A/G cg06533319 chr4:3265114 C4orf44 0.24 4.46 0.37 1.83e-5 Parental longevity (mother's age at death); TGCT cis rs826838 0.967 rs12823908 chr12:38845686 T/C cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs7552404 0.883 rs77773255 chr1:76217193 G/A cg10523679 chr1:76189770 ACADM 0.9 9.71 0.66 6.5e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.927 rs6832373 chr4:99051967 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.81 0.46 5e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12615966 1.000 rs61424916 chr2:105390188 C/A cg16465502 chr2:105461796 NA 0.78 5.03 0.41 1.66e-6 Pancreatic cancer; TGCT cis rs6570726 0.791 rs400329 chr6:145879442 A/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg16325326 chr1:53192061 ZYG11B 0.55 5.9 0.47 3.23e-8 Monocyte count; TGCT cis rs16957091 0.647 rs35838915 chr15:43357124 C/A cg17935677 chr15:44119062 WDR76 0.54 4.83 0.4 3.88e-6 MGMT methylation in smokers; TGCT cis rs3782455 1.000 rs79831570 chr12:114401608 T/C cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs765787 0.530 rs2433228 chr15:45515371 A/C cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg11410718 chr7:27170412 HOXA4 -0.47 -4.68 -0.39 7.38e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs9611565 0.568 rs5758441 chr22:42132888 C/A cg06481639 chr22:41940642 POLR3H 0.54 4.57 0.38 1.17e-5 Vitiligo; TGCT cis rs4766566 0.651 rs933307 chr12:111735537 A/C cg10833066 chr12:111807467 FAM109A -0.39 -7.2 -0.54 5.07e-11 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs616402 0.527 rs11584327 chr1:10578791 T/C cg17425144 chr1:10567563 PEX14 0.54 8.01 0.58 7.05e-13 Breast size; TGCT cis rs704 0.790 rs9913833 chr17:26718592 C/T cg10342447 chr17:26645325 TMEM97 -0.51 -4.91 -0.4 2.82e-6 Osteoprotegerin levels; TGCT cis rs2836633 0.895 rs62217513 chr21:40024416 A/T cg05519781 chr21:40033154 ERG 0.69 6.68 0.51 7.07e-10 Coronary artery disease; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg18110333 chr6:292329 DUSP22 0.68 7.38 0.55 2.02e-11 Menopause (age at onset); TGCT cis rs68170813 0.559 rs7783181 chr7:106977613 A/G cg02696742 chr7:106810147 HBP1 -0.68 -5.88 -0.47 3.53e-8 Coronary artery disease; TGCT cis rs1451375 0.959 rs17133878 chr7:50620927 T/C cg18232548 chr7:50535776 DDC 0.44 6.95 0.53 1.87e-10 Malaria; TGCT cis rs7570971 0.517 rs10187402 chr2:135771974 C/G cg07169764 chr2:136633963 MCM6 0.59 5.3 0.43 5.01e-7 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.72 0.46 7.47e-8 Alzheimer's disease; TGCT cis rs12653946 0.811 rs10866527 chr5:1891800 C/T cg22472608 chr5:1891194 NA -0.69 -8.93 -0.63 4.79e-15 Prostate cancer; TGCT cis rs7772486 0.790 rs6926076 chr6:146232804 C/T cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1568889 0.938 rs6484358 chr11:28260364 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.82 8.47 0.61 5.9e-14 Bipolar disorder; TGCT cis rs8030485 0.716 rs12899109 chr15:79410970 T/C cg17916960 chr15:79447300 NA 0.36 5.1 0.42 1.23e-6 Left ventricle wall thickness; TGCT cis rs12477438 0.765 rs6735801 chr2:99657995 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.56 -4.83 -0.4 4.01e-6 Chronic sinus infection; TGCT cis rs7666738 0.716 rs35195511 chr4:98859660 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.739 rs6138555 chr20:25242910 G/A cg16686733 chr20:25566563 NINL 0.52 4.9 0.4 2.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs35160687 0.901 rs34069316 chr2:86529792 T/C cg04877910 chr2:85804641 VAMP8 0.34 4.51 0.38 1.49e-5 Night sleep phenotypes; TGCT cis rs7824557 0.614 rs2736277 chr8:11218893 C/T cg21775007 chr8:11205619 TDH -0.64 -6.24 -0.49 6.32e-9 Retinal vascular caliber; TGCT cis rs597539 0.580 rs7935851 chr11:68731122 A/G cg21963583 chr11:68658836 MRPL21 0.35 5.7 0.46 8.33e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs2015828 chr4:98984594 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs601339 0.938 rs1696344 chr12:123183059 C/T cg11919336 chr12:123188078 GPR109A 0.64 7.67 0.57 4.36e-12 Adiponectin levels; TGCT cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs6500602 0.727 rs10451135 chr16:4580214 T/C cg09549813 chr16:4587862 C16orf5 -0.28 -4.51 -0.38 1.5e-5 Schizophrenia; TGCT cis rs7267979 0.816 rs6138593 chr20:25504492 A/G cg16686733 chr20:25566563 NINL 0.52 5.05 0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg25767906 chr1:53392781 SCP2 0.5 6.0 0.47 2e-8 Monocyte count; TGCT cis rs1525293 0.714 rs11773863 chr7:70511130 G/C cg21135135 chr7:70597687 WBSCR17 0.49 4.62 0.38 9.38e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs11148252 0.634 rs66849828 chr13:52714837 C/A cg00495681 chr13:53174319 NA 0.5 4.53 0.38 1.37e-5 Lewy body disease; TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.72 6.84 0.52 3.16e-10 Prudent dietary pattern; TGCT cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg21724239 chr8:58056113 NA 0.45 7.02 0.53 1.27e-10 Developmental language disorder (linguistic errors); TGCT cis rs4555082 0.874 rs2735828 chr14:105710486 C/A cg01266790 chr14:105781312 PACS2 0.54 4.56 0.38 1.2e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs7769051 0.803 rs12193474 chr6:133186168 T/C cg07930552 chr6:133119739 C6orf192 1.06 5.77 0.46 5.88e-8 Type 2 diabetes nephropathy; TGCT cis rs1395 0.634 rs62130713 chr2:27525661 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.59 7.3 0.55 3.08e-11 Blood metabolite levels; TGCT cis rs6582630 0.555 rs12828034 chr12:38274249 C/T cg26384229 chr12:38710491 ALG10B -0.55 -4.71 -0.39 6.64e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6540559 0.673 rs17317411 chr1:209961314 C/T cg22029157 chr1:209979665 IRF6 -0.75 -5.34 -0.43 4.34e-7 Cleft lip with or without cleft palate; TGCT cis rs6088580 0.634 rs1205345 chr20:32914699 A/G cg08999081 chr20:33150536 PIGU -0.26 -5.06 -0.41 1.44e-6 Glomerular filtration rate (creatinine); TGCT cis rs75718659 1.000 rs75718659 chr4:187743086 C/T cg02756176 chr4:187491362 NA 0.76 5.05 0.41 1.51e-6 Alzheimer disease and age of onset; TGCT cis rs7666738 0.830 rs10021709 chr4:99030587 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg01238044 chr22:24384105 GSTT1 -0.49 -4.56 -0.38 1.21e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7824557 0.564 rs2572394 chr8:11235393 A/G cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.95e-9 Retinal vascular caliber; TGCT cis rs8180040 0.764 rs4682852 chr3:47177772 C/T cg27129171 chr3:47204927 SETD2 0.76 9.9 0.66 2.25e-17 Colorectal cancer; TGCT cis rs9581857 0.547 rs77005033 chr13:28109793 A/G cg22138327 chr13:27999177 GTF3A 0.7 4.53 0.38 1.36e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs1005277 0.579 rs1740742 chr10:38518860 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs875971 0.862 rs10274883 chr7:66116091 C/T cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs1729951 0.546 rs361246 chr3:136695667 G/A cg21827317 chr3:136751795 NA 0.4 5.6 0.45 1.28e-7 Neuroticism; TGCT cis rs477895 1.000 rs2286614 chr11:64068310 C/T cg04317338 chr11:64019027 PLCB3 0.67 5.3 0.43 5.18e-7 Mean platelet volume; TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg19536664 chr17:6899085 ALOX12 -0.37 -5.88 -0.47 3.64e-8 Tonsillectomy; TGCT cis rs7020830 0.931 rs7027473 chr9:37132462 A/G cg14294708 chr9:37120828 ZCCHC7 1.31 20.37 0.88 2.24e-41 Schizophrenia; TGCT cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg07636037 chr3:49044803 WDR6 0.84 8.35 0.6 1.13e-13 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs739496 0.642 rs74849450 chr12:112208838 C/G cg10833066 chr12:111807467 FAM109A 0.36 4.67 0.39 7.74e-6 Platelet count; TGCT cis rs6912958 0.712 rs4707383 chr6:88330602 T/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs2414095 0.527 rs11636686 chr15:51542066 C/T cg19946085 chr15:51559439 CYP19A1 -0.32 -4.6 -0.38 1.02e-5 Follicule stimulating hormone;Hormone measurements;Total body bone mineral density; TGCT cis rs9399135 0.967 rs6909975 chr6:135315570 C/T cg24558204 chr6:135376177 HBS1L 0.46 4.59 0.38 1.09e-5 Red blood cell count; TGCT cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg05368731 chr17:41323189 NBR1 1.1 11.08 0.71 2.94e-20 Menopause (age at onset); TGCT cis rs2463822 1.000 rs2463825 chr11:62094493 G/A cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9467773 0.572 rs9467737 chr6:26381630 T/C cg05738196 chr6:26577821 NA -0.53 -5.5 -0.44 2.12e-7 Intelligence (multi-trait analysis); TGCT cis rs7246657 0.722 rs12974225 chr19:38240098 G/T cg18154014 chr19:37997991 ZNF793 -0.69 -4.92 -0.4 2.68e-6 Coronary artery calcification; TGCT cis rs10489202 0.632 rs12401555 chr1:168069473 G/C cg24449463 chr1:168025552 DCAF6 -0.52 -5.45 -0.44 2.58e-7 Schizophrenia; TGCT cis rs6545883 0.929 rs1838978 chr2:61540923 T/C cg15711740 chr2:61764176 XPO1 0.53 4.54 0.38 1.32e-5 Tuberculosis; TGCT cis rs12893668 0.628 rs57072546 chr14:104063723 T/C cg26031613 chr14:104095156 KLC1 -0.57 -4.75 -0.39 5.54e-6 Reticulocyte count; TGCT cis rs797680 0.856 rs7541687 chr1:93656588 A/G cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.89e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11785400 0.890 rs13279182 chr8:143720544 A/G cg10596483 chr8:143751796 JRK 0.55 5.67 0.45 9.72e-8 Schizophrenia; TGCT cis rs73416724 0.610 rs111981370 chr6:43255380 G/T cg24109273 chr6:43484729 YIPF3;POLR1C 1.04 5.36 0.43 3.95e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10791097 0.694 rs7106973 chr11:130758113 G/A cg14779329 chr11:130786720 SNX19 0.31 5.25 0.43 6.26e-7 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs916888 0.610 rs199529 chr17:44837217 A/C cg16228356 chr17:43848958 NA -0.26 -4.72 -0.39 6.14e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs10504390 0.585 rs117486340 chr8:66542077 G/A cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.29e-10 IgG glycosylation; TGCT cis rs950169 0.840 rs62019457 chr15:85102142 T/C cg17173187 chr15:85201210 NMB 0.53 5.53 0.44 1.83e-7 Schizophrenia; TGCT cis rs644799 0.562 rs1313288 chr11:95520695 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.55 5.67 0.45 9.5e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1200821 0.529 rs2505707 chr10:37801254 T/C cg25427524 chr10:38739819 LOC399744 -0.31 -5.4 -0.44 3.23e-7 Hemostatic factors and hematological phenotypes; TGCT cis rs9291683 0.552 rs11736410 chr4:10017241 G/A cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Bone mineral density; TGCT trans rs12655019 0.920 rs6882657 chr5:56222739 C/T cg25190722 chr1:3801660 DFFB 0.67 7.44 0.56 1.48e-11 Breast cancer (early onset); TGCT cis rs68170813 0.605 rs75659533 chr7:107134987 A/G cg02696742 chr7:106810147 HBP1 -0.64 -5.08 -0.41 1.37e-6 Coronary artery disease; TGCT cis rs13242816 0.881 rs56034786 chr7:116106360 T/C cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT cis rs916888 0.610 rs199444 chr17:44818276 T/C cg15921436 chr17:44337874 NA 0.43 6.5 0.5 1.79e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs79387448 0.655 rs11891827 chr2:102951182 A/G cg09003973 chr2:102972529 NA 1.4 9.44 0.65 2.87e-16 Gut microbiota (bacterial taxa); TGCT cis rs9468199 0.510 rs72847349 chr6:27805303 T/C cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs17376456 1.000 rs12187701 chr5:93522290 A/G cg21475434 chr5:93447410 FAM172A 0.61 4.48 0.37 1.68e-5 Diabetic retinopathy; TGCT cis rs7412746 0.621 rs7518156 chr1:150945794 A/C cg09365446 chr1:150670422 GOLPH3L 0.35 4.82 0.4 4.2e-6 Melanoma; TGCT cis rs1348850 0.914 rs10194648 chr2:178337031 G/A cg22681709 chr2:178499509 PDE11A -0.36 -4.71 -0.39 6.46e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT trans rs7819412 0.511 rs2409798 chr8:11435564 C/T cg15556689 chr8:8085844 FLJ10661 -0.77 -7.17 -0.54 6.04e-11 Triglycerides; TGCT cis rs6430585 0.528 rs16832205 chr2:136684632 G/A cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs6684514 1.000 rs2277870 chr1:156246792 C/T cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7615952 0.932 rs13086087 chr3:125646281 A/C cg05084668 chr3:125655381 ALG1L -0.75 -6.07 -0.48 1.41e-8 Blood pressure (smoking interaction); TGCT trans rs561341 0.882 rs72825748 chr17:30367396 G/A cg20587970 chr11:113659929 NA -1.09 -13.5 -0.77 4.23e-26 Hip circumference adjusted for BMI; TGCT cis rs56104184 0.775 rs73061699 chr19:49400511 T/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs10484885 0.648 rs2777848 chr6:90535993 G/A cg13799429 chr6:90582589 CASP8AP2 -0.54 -6.32 -0.49 4.2e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4378999 0.660 rs61108141 chr3:50966191 A/G ch.3.1075622R chr3:50010873 RBM6 0.36 4.56 0.38 1.23e-5 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); TGCT cis rs6121246 0.609 rs6088997 chr20:30289824 A/G cg13852791 chr20:30311386 BCL2L1 -0.8 -7.2 -0.54 4.99e-11 Mean corpuscular hemoglobin; TGCT cis rs6987853 0.933 rs2923401 chr8:42442208 T/C cg20539142 chr8:42623718 CHRNA6 -0.2 -4.82 -0.4 4.2e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs8180040 0.739 rs11719306 chr3:47184182 G/A cg27129171 chr3:47204927 SETD2 0.76 9.89 0.66 2.32e-17 Colorectal cancer; TGCT cis rs854765 0.583 rs4925129 chr17:17807186 A/G cg09796270 chr17:17721594 SREBF1 0.26 5.44 0.44 2.75e-7 Total body bone mineral density; TGCT cis rs3780378 0.935 rs1028912 chr9:5050369 G/C cg02405213 chr9:5042618 JAK2 -0.58 -7.5 -0.56 1.09e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs734999 0.588 rs2764848 chr1:2530694 G/A cg18854424 chr1:2615690 NA -0.46 -5.36 -0.43 3.84e-7 Ulcerative colitis; TGCT cis rs1215050 0.791 rs684210 chr4:98678740 G/C cg05340658 chr4:99064831 C4orf37 0.43 5.4 0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs992157 0.710 rs6719789 chr2:219057810 G/T cg00012203 chr2:219082015 ARPC2 -0.85 -11.09 -0.71 2.86e-20 Colorectal cancer; TGCT trans rs7618501 0.699 rs6446187 chr3:49907111 C/A cg21659725 chr3:3221576 CRBN 0.78 9.37 0.64 4.19e-16 Intelligence (multi-trait analysis); TGCT cis rs7940866 0.838 rs10736592 chr11:130800572 C/T cg05962950 chr11:130786565 SNX19 0.72 7.35 0.55 2.31e-11 Schizophrenia; TGCT cis rs6121246 0.567 rs6120890 chr20:30207659 T/G cg18721089 chr20:30220636 NA -0.57 -6.19 -0.49 7.9e-9 Mean corpuscular hemoglobin; TGCT cis rs597539 0.652 rs513615 chr11:68705504 G/T cg21862992 chr11:68658383 NA 0.48 6.6 0.51 1.06e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7914558 0.933 rs10883814 chr10:104737404 T/C cg04362960 chr10:104952993 NT5C2 0.6 5.42 0.44 2.99e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2072499 0.900 rs2248080 chr1:156195971 T/A cg06970220 chr1:156163860 SLC25A44 0.74 5.98 0.47 2.22e-8 Testicular germ cell tumor; TGCT cis rs2832191 1.000 rs9984793 chr21:30486471 T/C cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs1008375 0.966 rs12503540 chr4:17698781 C/G cg18681998 chr4:17616180 MED28 -0.76 -7.28 -0.55 3.36e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9325144 0.555 rs11183215 chr12:38693127 G/A cg26384229 chr12:38710491 ALG10B -0.66 -6.15 -0.48 1e-8 Morning vs. evening chronotype; TGCT cis rs2204008 0.701 rs3898237 chr12:38219714 A/G cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT trans rs1974653 0.672 rs9606247 chr22:20087473 T/A cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs727505 1.000 rs10246424 chr7:124494861 A/G cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs7095607 1.000 rs7079974 chr10:69959397 G/A cg18986048 chr10:69913749 MYPN 0.45 4.86 0.4 3.52e-6 Lung function (FVC); TGCT cis rs11578119 0.933 rs115701628 chr1:170421735 C/T cg09767346 chr1:170501363 GORAB 0.71 5.65 0.45 1.04e-7 Male-pattern baldness; TGCT cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg04025307 chr7:1156635 C7orf50 0.23 5.23 0.43 6.91e-7 Longevity;Endometriosis; TGCT cis rs875971 0.660 rs10229345 chr7:65982168 G/C cg18876405 chr7:65276391 NA 0.4 6.23 0.49 6.75e-9 Aortic root size; TGCT cis rs6879260 1.000 rs10903252 chr5:179733934 T/C cg23248424 chr5:179741104 GFPT2 -0.38 -7.07 -0.54 9.78e-11 Height; TGCT cis rs4700695 0.925 rs4700090 chr5:65412434 C/T cg21114390 chr5:65439923 SFRS12 -0.62 -4.72 -0.39 6.24e-6 Facial morphology (factor 19); TGCT cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg03264133 chr6:25882463 NA 0.52 5.26 0.43 6.21e-7 Blood metabolite levels; TGCT cis rs9926296 0.605 rs7205053 chr16:89856763 G/C cg21285383 chr16:89894308 SPIRE2 0.45 7.12 0.54 7.61e-11 Vitiligo; TGCT cis rs7833790 0.777 rs6473301 chr8:82691340 A/G cg06027949 chr8:82754900 SNX16 -0.67 -4.47 -0.37 1.75e-5 Diastolic blood pressure; TGCT cis rs11249608 0.548 rs7733072 chr5:178456007 A/G cg21905437 chr5:178450457 ZNF879 0.44 4.57 0.38 1.16e-5 Pubertal anthropometrics; TGCT cis rs17376456 0.825 rs17314762 chr5:93231200 C/T cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.17e-13 Diabetic retinopathy; TGCT cis rs933688 1.000 rs6865495 chr5:90746424 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.11 10.58 0.69 4.97e-19 Smoking behavior; TGCT cis rs17376456 0.825 rs13165400 chr5:93091427 G/A cg09848695 chr5:92956644 FAM172A;MIR2277 0.63 4.43 0.37 2.01e-5 Diabetic retinopathy; TGCT cis rs3008870 1.000 rs7511948 chr1:67430427 A/G cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs4889855 0.530 rs72856551 chr17:78552267 G/T cg16591659 chr17:78472290 NA 0.28 4.46 0.37 1.84e-5 Fractional excretion of uric acid; TGCT cis rs9517320 0.534 rs9554478 chr13:99187792 G/A cg07423050 chr13:99094983 FARP1 -0.28 -5.53 -0.44 1.83e-7 Longevity; TGCT cis rs17767294 0.708 rs72847323 chr6:27744490 A/T cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs5750830 0.569 rs5750809 chr22:39791491 T/G cg02038168 chr22:39784481 NA -0.73 -6.0 -0.47 2.05e-8 Intelligence (multi-trait analysis); TGCT trans rs7613875 0.654 rs3774751 chr3:50209053 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.79 -8.22 -0.59 2.36e-13 Body mass index; TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs9357506 1.000 rs9381442 chr6:46313545 C/T cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs832540 0.552 rs252924 chr5:56205643 A/G cg12311346 chr5:56204834 C5orf35 -0.54 -5.44 -0.44 2.71e-7 Coronary artery disease; TGCT cis rs782590 0.774 rs2627773 chr2:55900459 A/G cg18811423 chr2:55921094 PNPT1 0.65 6.76 0.52 4.79e-10 Metabolic syndrome; TGCT cis rs6754311 0.593 rs7355359 chr2:136462441 C/T cg07169764 chr2:136633963 MCM6 -0.67 -6.11 -0.48 1.16e-8 Mosquito bite size; TGCT cis rs9733 0.596 rs72702523 chr1:150650425 G/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.66 0.39 8.11e-6 Tonsillectomy; TGCT cis rs250677 0.687 rs3095947 chr5:148436728 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs1348850 0.793 rs6736390 chr2:178480314 T/C cg22681709 chr2:178499509 PDE11A -0.47 -5.69 -0.45 8.85e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT trans rs561341 1.000 rs550923 chr17:30327013 G/C cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs7727544 0.716 rs4705928 chr5:131578637 A/G cg24060327 chr5:131705240 SLC22A5 0.54 5.06 0.41 1.48e-6 Blood metabolite levels; TGCT cis rs1577917 0.916 rs7759727 chr6:86518878 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.19 -0.42 8.31e-7 Response to antipsychotic treatment; TGCT cis rs137603 0.602 rs9611146 chr22:39718120 G/T cg17798944 chr22:39715225 SNORD43;RPL3 -0.68 -7.25 -0.55 3.85e-11 Primary biliary cholangitis; TGCT cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.03 -0.76 5.66e-25 Vitiligo; TGCT cis rs10791323 0.569 rs546381 chr11:133760651 T/G cg15485101 chr11:133734466 NA 0.39 5.51 0.44 2.02e-7 Childhood ear infection; TGCT cis rs826838 0.616 rs10880754 chr12:38628154 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs9894429 1.000 rs7222241 chr17:79574714 C/G cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg03303774 chr4:1407052 NA 0.29 4.67 0.39 7.71e-6 Obesity-related traits; TGCT cis rs2594989 0.673 rs9854573 chr3:11602577 C/T cg00170343 chr3:11313890 ATG7 -0.72 -5.16 -0.42 9.38e-7 Circulating chemerin levels; TGCT cis rs524281 0.861 rs12049852 chr11:65884702 T/C cg00563793 chr11:65837595 PACS1 0.55 4.63 0.38 9.13e-6 Electroencephalogram traits; TGCT cis rs801193 0.569 rs13242290 chr7:66121885 G/A cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.76 5.03 0.41 1.68e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7017914 0.905 rs1493203 chr8:71926507 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs10791097 0.592 rs4936122 chr11:130734264 A/C cg12179176 chr11:130786555 SNX19 0.81 9.76 0.66 4.74e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9952991 0.582 rs658158 chr18:12823402 T/G cg23544223 chr18:12777786 NA 0.53 4.68 0.39 7.25e-6 Inflammatory skin disease; TGCT cis rs2178146 0.535 rs1918826 chr16:86451996 C/T cg11165158 chr16:86613094 FOXL1 -0.35 -4.78 -0.39 4.86e-6 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg09737314 chr17:6899359 ALOX12 0.51 5.31 0.43 4.82e-7 Tonsillectomy; TGCT cis rs3617 0.539 rs11922975 chr3:52936763 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.65 -0.39 8.52e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs78487399 1.000 rs79611878 chr2:43844803 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.58 0.38 1.12e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs909674 0.818 rs5750833 chr22:39843091 C/A cg05872129 chr22:39784769 NA -0.96 -9.51 -0.65 1.99e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6598955 0.671 rs12142535 chr1:26589698 T/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs11741688 0.557 rs6600994 chr5:178336005 T/A cg08270223 chr5:178322770 ZFP2 -0.37 -5.49 -0.44 2.14e-7 Sleep duration; TGCT cis rs968451 0.789 rs1569498 chr22:39714704 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.85 9.24 0.64 8.48e-16 Primary biliary cholangitis; TGCT cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.63 6.67 0.51 7.58e-10 Height; TGCT cis rs79057730 0.639 rs6463933 chr7:793954 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.37 0.43 3.82e-7 Initial pursuit acceleration; TGCT cis rs9814567 1.000 rs4417907 chr3:134291363 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.53 -0.65 1.7e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs8073060 0.586 rs72829922 chr17:34044809 G/A cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg00533182 chr8:145726136 PPP1R16A 0.27 4.58 0.38 1.11e-5 Age at first birth; TGCT cis rs4919694 0.901 rs113541728 chr10:104716771 A/T cg04362960 chr10:104952993 NT5C2 1.07 7.15 0.54 6.49e-11 Arsenic metabolism; TGCT trans rs2832077 0.689 rs2832055 chr21:30132382 C/G cg14791747 chr16:20752902 THUMPD1 -0.81 -7.05 -0.53 1.13e-10 Cognitive test performance; TGCT cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 8.11 0.59 4.07e-13 Platelet count; TGCT cis rs1372520 0.684 rs1442148 chr4:90748846 T/A cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs11690935 0.632 rs34242651 chr2:172553999 G/A cg13550731 chr2:172543902 DYNC1I2 0.69 6.09 0.48 1.33e-8 Schizophrenia; TGCT cis rs11098499 0.532 rs4833624 chr4:120585497 C/T cg09307838 chr4:120376055 NA 0.59 5.6 0.45 1.31e-7 Corneal astigmatism; TGCT cis rs854765 0.964 rs854764 chr17:18011750 A/G cg04398451 chr17:18023971 MYO15A 0.31 5.06 0.41 1.47e-6 Total body bone mineral density; TGCT cis rs7714584 1.000 rs11746807 chr5:150300419 G/A cg22134413 chr5:150180641 NA 1.01 7.24 0.55 4.17e-11 Crohn's disease; TGCT cis rs593982 0.858 rs663797 chr11:65552740 A/G cg08755490 chr11:65554678 OVOL1 1.41 11.56 0.72 2e-21 Atopic dermatitis; TGCT cis rs2637266 1.000 rs2130795 chr10:78333892 C/G cg18941641 chr10:78392320 NA 0.41 4.98 0.41 2.05e-6 Pulmonary function; TGCT cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg06221963 chr1:154839813 KCNN3 -0.71 -11.67 -0.72 1.1e-21 Prostate cancer; TGCT cis rs3947 0.688 rs1293326 chr8:11694765 G/C cg02840367 chr8:11660030 FDFT1 0.89 6.56 0.51 1.3e-9 Blood protein levels; TGCT cis rs4972539 0.576 rs2358090 chr2:174098461 G/C cg08748100 chr2:173100097 NA 0.45 4.93 0.4 2.59e-6 Parental longevity (mother's age at death); TGCT cis rs17376456 0.825 rs13182631 chr5:93115701 A/G cg25358565 chr5:93447407 FAM172A 0.91 8.22 0.59 2.27e-13 Diabetic retinopathy; TGCT cis rs7213347 0.707 rs216215 chr17:2140668 C/T cg20777128 chr17:1945076 DPH1;OVCA2 -0.5 -4.62 -0.38 9.49e-6 Total body bone mineral density; TGCT cis rs3793683 0.928 rs2148666 chr10:134553785 A/G cg27286337 chr10:134555280 INPP5A 0.48 7.35 0.55 2.3e-11 Migraine; TGCT cis rs4722166 0.630 rs1829927 chr7:22779918 G/A cg26061582 chr7:22766209 IL6 0.57 7.36 0.55 2.27e-11 Lung cancer; TGCT cis rs892864 0.685 rs6886402 chr5:127738895 C/A cg01939274 chr5:127874478 FBN2 0.91 4.52 0.38 1.44e-5 Multiple system atrophy; TGCT cis rs10170846 0.861 rs12694582 chr2:223521955 G/C cg25565276 chr2:223520875 FARSB 0.55 4.58 0.38 1.11e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs9430161 0.564 rs12081176 chr1:11034145 T/C cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs1577917 1.000 rs11758849 chr6:86708262 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.57 -0.45 1.53e-7 Response to antipsychotic treatment; TGCT cis rs7674212 1.000 rs7691873 chr4:103987899 C/T cg16532752 chr4:104119610 CENPE 0.49 4.67 0.39 7.71e-6 Type 2 diabetes; TGCT cis rs6964587 0.967 rs10248102 chr7:91699779 G/A cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs55910451 0.723 rs3793707 chr10:5798730 G/T cg09234995 chr10:5726438 C10orf18 0.48 4.43 0.37 2.01e-5 Breast cancer; TGCT cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg17264618 chr3:40429014 ENTPD3 -0.32 -4.45 -0.37 1.9e-5 Renal cell carcinoma; TGCT cis rs9467773 0.596 rs3001369 chr6:26670969 C/T cg26531700 chr6:26746687 NA 0.59 5.15 0.42 9.94e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 1.000 rs441109 chr1:76120430 T/G cg03433033 chr1:76189801 ACADM -0.84 -10.12 -0.67 6.47e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs904251 0.797 rs1757177 chr6:37486370 C/T cg08126542 chr6:37504118 NA -0.44 -5.58 -0.45 1.46e-7 Cognitive performance; TGCT cis rs1552244 0.572 rs3894323 chr3:10168967 G/A cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs801193 0.935 rs3800820 chr7:66147178 C/T cg00343986 chr7:65444356 GUSB -0.22 -5.01 -0.41 1.84e-6 Aortic root size; TGCT cis rs1475911 1.000 rs34421316 chr21:43513989 C/T cg24372256 chr21:43528868 UMODL1;C21orf128 -0.27 -4.91 -0.4 2.77e-6 IgG glycosylation; TGCT cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs875971 0.825 rs4587224 chr7:65736182 G/A cg11764359 chr7:65958608 NA -0.57 -5.12 -0.42 1.12e-6 Aortic root size; TGCT cis rs2458413 0.563 rs2458419 chr8:105337141 G/C cg04554929 chr8:105342491 NA -0.61 -9.81 -0.66 3.55e-17 Paget's disease; TGCT cis rs12802200 0.561 rs7937217 chr11:571967 T/C cg27205902 chr11:1006985 AP2A2 0.27 4.47 0.37 1.76e-5 Systemic lupus erythematosus; TGCT cis rs4319547 0.956 rs7316149 chr12:123063912 G/A cg23029597 chr12:123009494 RSRC2 -0.31 -5.09 -0.42 1.3e-6 Body mass index; TGCT trans rs17685 0.753 rs1637051 chr7:75730659 G/A cg19862616 chr7:65841803 NCRNA00174 0.49 7.91 0.58 1.24e-12 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs3027009 0.881 rs61828178 chr1:159159041 G/T cg18972751 chr1:158261555 CD1C -0.45 -4.74 -0.39 5.84e-6 Lean body mass and age at menarche (combined); TGCT cis rs6088580 0.609 rs945674 chr20:32964247 G/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs1008375 1.000 rs6849704 chr4:17652031 G/C cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10057188 1.000 rs12697888 chr5:77859646 C/T cg06873401 chr5:77792105 LHFPL2 -0.24 -4.54 -0.38 1.32e-5 Pulse pressure; TGCT cis rs2836974 0.644 rs11088471 chr21:40699313 A/G cg17971929 chr21:40555470 PSMG1 -0.68 -5.94 -0.47 2.67e-8 Cognitive function; TGCT cis rs17068510 0.572 rs11780696 chr8:3875497 A/G cg25338036 chr8:3047536 CSMD1 -0.46 -4.88 -0.4 3.19e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg00786635 chr1:25594202 NA -0.53 -5.66 -0.45 9.94e-8 Erythrocyte sedimentation rate; TGCT cis rs9457247 1.000 rs385113 chr6:167403971 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT trans rs6089829 0.962 rs6062393 chr20:61663230 G/A cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs896854 0.738 rs527234 chr8:95963798 C/G cg13393036 chr8:95962371 TP53INP1 0.56 6.99 0.53 1.51e-10 Type 2 diabetes; TGCT cis rs6121246 0.529 rs6058152 chr20:30178107 G/A cg13852791 chr20:30311386 BCL2L1 0.69 4.53 0.38 1.36e-5 Mean corpuscular hemoglobin; TGCT cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg06640241 chr16:89574553 SPG7 0.79 9.12 0.63 1.68e-15 Multiple myeloma (IgH translocation); TGCT cis rs6450176 0.585 rs255761 chr5:53321956 G/T ch.5.1024479R chr5:53302184 ARL15 -0.52 -4.51 -0.38 1.47e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs3743162 0.553 rs12915656 chr15:85415580 G/C cg11189052 chr15:85197271 WDR73 0.65 4.78 0.39 4.97e-6 Alzheimer's disease (age of onset); TGCT cis rs2235642 0.928 rs2076435 chr16:1607574 C/T cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.75 -0.46 6.52e-8 Coronary artery disease; TGCT cis rs988712 0.705 rs11030104 chr11:27684517 C/T cg10635145 chr11:27742435 BDNF 0.44 6.19 0.49 8.21e-9 Obesity; TGCT cis rs853679 0.567 rs1005126 chr6:28367623 C/G cg18815343 chr6:28367644 ZSCAN12 -0.52 -4.67 -0.39 7.85e-6 Depression; TGCT cis rs651907 0.967 rs641432 chr3:101587566 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.46 4.79 0.4 4.6e-6 Colorectal cancer; TGCT trans rs7726839 0.574 rs12522955 chr5:639231 C/A cg25482853 chr8:67687455 SGK3 1.22 10.53 0.69 6.33e-19 Obesity-related traits; TGCT cis rs10779751 0.959 rs2300091 chr1:11266711 C/T cg08854313 chr1:11322531 MTOR 0.92 10.31 0.68 2.23e-18 Body mass index; TGCT cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs7599312 1.000 rs7599312 chr2:213413231 C/T cg16329650 chr2:213403929 ERBB4 0.75 6.37 0.5 3.31e-9 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.830 rs10001701 chr4:98918871 G/C cg18180107 chr4:99064573 C4orf37 0.55 5.02 0.41 1.78e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2862064 0.872 rs2902132 chr5:156445525 C/T cg12943317 chr5:156479607 HAVCR1 -0.45 -5.71 -0.46 7.96e-8 Platelet count; TGCT cis rs7267979 1.000 rs2387880 chr20:25377787 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs709400 0.628 rs11622320 chr14:103912194 A/T cg12935359 chr14:103987150 CKB -0.34 -4.95 -0.41 2.34e-6 Body mass index; TGCT cis rs7731657 0.537 rs72801791 chr5:130374799 T/C cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT trans rs7726839 0.540 rs56325086 chr5:640728 G/A cg25482853 chr8:67687455 SGK3 1.21 10.75 0.69 1.86e-19 Obesity-related traits; TGCT cis rs5750830 0.621 rs5757665 chr22:39821641 A/G cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs11644362 0.966 rs4781348 chr16:12986742 A/C cg06890432 chr16:12997467 SHISA9 -0.6 -6.4 -0.5 2.87e-9 Positive affect;Subjective well-being; TGCT cis rs9329221 0.905 rs6601451 chr8:10243681 C/G cg21775007 chr8:11205619 TDH -0.52 -4.87 -0.4 3.33e-6 Neuroticism; TGCT cis rs11190604 1.000 rs7099965 chr10:102301165 A/G cg16342193 chr10:102329863 NA -0.4 -4.97 -0.41 2.14e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9796 0.553 rs7171437 chr15:41315168 G/A cg26219294 chr15:41245916 CHAC1 0.36 4.45 0.37 1.89e-5 Menopause (age at onset); TGCT cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs76935404 0.811 rs12151139 chr19:41433543 A/G cg19493303 chr19:41414353 NA -0.43 -5.18 -0.42 8.63e-7 nicotine metabolite ratio in current smokers; TGCT cis rs3820068 0.705 rs2145397 chr1:15896199 G/A cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs137887 0.935 rs137885 chr22:50463231 T/C cg17558497 chr22:50464837 TTLL8 0.2 4.45 0.37 1.92e-5 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs9364220 0.662 rs2087570 chr6:168494037 C/T cg02770688 chr6:168491649 NA -0.29 -5.48 -0.44 2.29e-7 Attention deficit hyperactivity disorder (inattention symptoms);Attention deficit hyperactivity disorder (combined symptoms); TGCT cis rs11715566 0.515 rs11713893 chr3:117606479 A/G cg15509235 chr3:117715573 NA 0.56 5.14 0.42 1.04e-6 Menarche (age at onset); TGCT cis rs611744 0.967 rs597992 chr8:109193808 A/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs8097348 0.817 rs8096095 chr18:1670019 A/C cg07100532 chr18:713085 ENOSF1 -0.4 -4.45 -0.37 1.87e-5 Exercise (leisure time); TGCT cis rs10782582 0.586 rs112368938 chr1:76336339 C/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs2412459 0.611 rs4924402 chr15:40245754 C/T cg22077389 chr15:40226273 EIF2AK4 -0.69 -4.44 -0.37 1.97e-5 Response to haloperidol in psychosis; TGCT cis rs7568458 0.846 rs7605975 chr2:85772548 C/T cg17127132 chr2:85788382 GGCX 0.68 6.59 0.51 1.12e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT cis rs1385374 0.858 rs11059930 chr12:129297860 T/C cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs6750047 0.625 rs336036 chr2:38261143 C/T cg07380506 chr2:38303506 CYP1B1 -0.54 -4.73 -0.39 6.12e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs2439831 0.850 rs3736180 chr15:44106624 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.27 0.49 5.48e-9 Lung cancer in ever smokers; TGCT cis rs8013055 0.846 rs10139744 chr14:105974696 G/A cg19700328 chr14:106028568 NA -0.49 -5.23 -0.43 6.91e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs6545883 0.894 rs10496092 chr2:61524679 C/T cg15711740 chr2:61764176 XPO1 0.55 4.72 0.39 6.17e-6 Tuberculosis; TGCT cis rs4808199 0.948 rs757001 chr19:19448808 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.63 4.56 0.38 1.23e-5 Nonalcoholic fatty liver disease; TGCT cis rs4494114 0.967 rs6679612 chr1:39313228 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.28 -0.49 5.09e-9 Blood protein levels; TGCT cis rs114540395 0.858 rs17767748 chr10:103285900 A/G cg09701700 chr10:104194843 MIR146B 0.46 4.76 0.39 5.28e-6 Schizophrenia; TGCT cis rs1670533 0.818 rs6835141 chr4:1070140 G/T cg20887711 chr4:1340912 KIAA1530 0.63 4.95 0.41 2.32e-6 Recombination rate (females); TGCT cis rs7729723 0.568 rs11242430 chr5:137822866 C/A cg19169342 chr5:137827400 NA 0.32 4.46 0.37 1.78e-5 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs2688608 0.592 rs7923045 chr10:75487498 A/T cg19442545 chr10:75533431 FUT11 -0.36 -5.68 -0.45 9.11e-8 Inflammatory bowel disease; TGCT cis rs10465746 0.967 rs11576870 chr1:84333301 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg11644478 chr21:40555479 PSMG1 -0.58 -5.0 -0.41 1.94e-6 Cognitive function; TGCT cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg20849893 chr7:64541193 NA -0.48 -4.89 -0.4 3.1e-6 Calcium levels; TGCT cis rs637571 0.522 rs491973 chr11:65727301 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.6 6.03 0.48 1.75e-8 Eosinophil percentage of white cells; TGCT cis rs2230307 0.536 rs7530361 chr1:100462860 T/C cg24955406 chr1:100503596 HIAT1 0.72 4.68 0.39 7.51e-6 Carotid intima media thickness; TGCT cis rs1865760 1.000 rs1865760 chr6:25916979 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.18 0.49 8.59e-9 Height; TGCT cis rs7617773 0.746 rs11713476 chr3:48375434 C/T cg11946769 chr3:48343235 NME6 0.74 6.6 0.51 1.05e-9 Coronary artery disease; TGCT cis rs7027203 0.797 rs7870672 chr9:96606693 A/C cg13679303 chr9:96623674 NA -0.66 -10.78 -0.7 1.64e-19 DNA methylation (variation); TGCT cis rs78456975 1.000 rs6712176 chr2:1556393 C/T cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs523522 0.962 rs2393590 chr12:120913900 G/A cg12219531 chr12:120966889 COQ5 0.83 7.33 0.55 2.6e-11 High light scatter reticulocyte count; TGCT cis rs2239785 0.920 rs136178 chr22:36664339 A/G cg15716373 chr22:36655542 APOL1 -0.48 -5.1 -0.42 1.26e-6 Glomerulosclerosis; TGCT cis rs11167764 1.000 rs6580220 chr5:141480558 G/A cg23435118 chr5:141488016 NDFIP1 -0.3 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs754133 0.535 rs7297416 chr12:54443090 A/C cg16264616 chr12:54390824 NA 0.38 5.37 0.43 3.73e-7 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs9611565 0.877 rs3817999 chr22:41747717 A/G cg17554472 chr22:41940697 POLR3H 0.48 5.29 0.43 5.25e-7 Vitiligo; TGCT cis rs6460942 0.915 rs6968695 chr7:12443878 G/C cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs6964587 1.000 rs2282972 chr7:91666369 C/T cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs7659604 0.791 rs57316471 chr4:122663939 A/G cg19748678 chr4:122722346 EXOSC9 0.73 7.37 0.55 2.08e-11 Type 2 diabetes; TGCT cis rs78487399 0.808 rs13405076 chr2:43735353 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.84 -0.4 3.79e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg03161606 chr19:29218774 NA 0.6 5.84 0.46 4.28e-8 Methadone dose in opioid dependence; TGCT cis rs56104184 0.830 rs17206679 chr19:49342237 C/G cg17863274 chr19:49399704 TULP2 -0.48 -6.07 -0.48 1.44e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9926296 0.744 rs164748 chr16:89708292 C/G cg26513180 chr16:89883248 FANCA -0.61 -5.73 -0.46 7.18e-8 Vitiligo; TGCT cis rs12477438 0.798 rs9679602 chr2:99577827 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.68 5.97 0.47 2.3e-8 Chronic sinus infection; TGCT cis rs7615952 0.673 rs115942855 chr3:125601960 G/A cg05084668 chr3:125655381 ALG1L -0.75 -4.68 -0.39 7.51e-6 Blood pressure (smoking interaction); TGCT cis rs2197308 0.703 rs10880251 chr12:37903297 G/A cg13010199 chr12:38710504 ALG10B 0.67 5.38 0.44 3.57e-7 Morning vs. evening chronotype; TGCT cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg07507251 chr3:52567010 NT5DC2 0.46 6.66 0.51 7.92e-10 Bipolar disorder; TGCT cis rs2404618 0.624 rs28439223 chr8:1476901 C/G cg13402656 chr8:1511478 DLGAP2 -0.34 -5.55 -0.45 1.69e-7 Lung cancer; TGCT cis rs7615952 0.800 rs12489350 chr3:125644116 T/C cg05084668 chr3:125655381 ALG1L -0.76 -6.22 -0.49 7.13e-9 Blood pressure (smoking interaction); TGCT cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg13397359 chr6:42928475 GNMT 0.73 6.81 0.52 3.7e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4253772 0.551 rs9615936 chr22:46686328 C/G cg24881330 chr22:46731750 TRMU 1.03 5.41 0.44 3.06e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7192750 0.586 rs8051038 chr16:71870700 G/A cg06353428 chr16:71660113 MARVELD3 0.8 7.26 0.55 3.8e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7666738 0.830 rs13106434 chr4:98991651 T/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9443645 0.901 rs1567167 chr6:79553827 C/T cg05283184 chr6:79620031 NA -0.2 -4.67 -0.39 7.72e-6 Intelligence (multi-trait analysis); TGCT cis rs245880 0.740 rs245890 chr7:29190720 T/C cg17163760 chr7:29186267 CPVL -0.44 -5.54 -0.45 1.73e-7 Warfarin maintenance dose; TGCT cis rs2288073 0.965 rs6545338 chr2:24422156 C/T cg02683114 chr2:24398427 C2orf84 -0.25 -5.67 -0.45 9.72e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg18402987 chr7:1209562 NA 0.76 6.39 0.5 3e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9325144 0.560 rs11183150 chr12:38674698 A/G cg26384229 chr12:38710491 ALG10B -0.64 -5.82 -0.46 4.63e-8 Morning vs. evening chronotype; TGCT cis rs2354432 1.000 rs10900325 chr1:146692174 C/T cg25205988 chr1:146714368 CHD1L -1.33 -7.77 -0.57 2.56e-12 Mitochondrial DNA levels; TGCT cis rs7666738 0.716 rs114187620 chr4:98819534 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.25 0.43 6.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs79057730 0.528 rs6965219 chr7:821807 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.65 6.04 0.48 1.67e-8 Initial pursuit acceleration; TGCT cis rs7666738 0.830 rs28867087 chr4:98880349 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2046867 0.862 rs2174062 chr3:72826901 T/C cg25664220 chr3:72788482 NA -0.54 -6.72 -0.52 5.99e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs7095607 0.813 rs7913516 chr10:69927932 G/A cg18986048 chr10:69913749 MYPN 0.44 5.03 0.41 1.71e-6 Lung function (FVC); TGCT cis rs7513165 0.935 rs4951319 chr1:204162230 A/G cg12731349 chr1:204159619 KISS1 0.44 5.07 0.41 1.38e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs2228479 0.541 rs13335395 chr16:89952843 T/A cg06558623 chr16:89946397 TCF25 0.43 5.1 0.42 1.26e-6 Skin colour saturation; TGCT cis rs4776059 0.761 rs12594964 chr15:52900208 G/A cg25063058 chr15:52860530 ARPP19 -0.56 -4.44 -0.37 1.98e-5 Schizophrenia; TGCT cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.85 -9.45 -0.65 2.76e-16 Age at first birth; TGCT cis rs5769707 0.967 rs1018812 chr22:50010073 C/T cg10356904 chr22:49881777 NA -0.24 -4.81 -0.4 4.35e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs265548 0.608 rs265545 chr19:17903465 C/T cg03316864 chr19:17906309 B3GNT3 0.43 4.95 0.41 2.36e-6 Tumor biomarkers; TGCT cis rs1568889 0.838 rs11030229 chr11:28173634 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 10.74 0.69 1.97e-19 Bipolar disorder; TGCT cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7223966 1.000 rs7209758 chr17:61913621 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg14983838 chr19:29218262 NA 0.75 6.87 0.53 2.69e-10 Methadone dose in opioid dependence; TGCT cis rs4478858 0.684 rs10798838 chr1:31719450 G/A cg00250761 chr1:31883323 NA -0.26 -4.74 -0.39 5.75e-6 Alcohol dependence; TGCT cis rs208520 1.000 rs12195505 chr6:66986279 T/A cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg13397359 chr6:42928475 GNMT 0.69 6.21 0.49 7.25e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7618915 0.547 rs11714419 chr3:52628816 A/G cg10802521 chr3:52805072 NEK4 -0.7 -8.8 -0.62 9.89e-15 Bipolar disorder; TGCT cis rs739496 0.527 rs61612992 chr12:112358064 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs11785400 0.762 rs7460801 chr8:143730972 C/A cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.79e-7 Schizophrenia; TGCT cis rs11578119 0.933 rs4656776 chr1:170469838 C/T cg09767346 chr1:170501363 GORAB -0.67 -5.36 -0.43 3.85e-7 Male-pattern baldness; TGCT cis rs11809207 0.859 rs61776644 chr1:26505548 T/C cg03844060 chr1:26490628 NA 0.28 5.07 0.41 1.43e-6 Height; TGCT cis rs7100689 0.646 rs2486302 chr10:82076600 G/A cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs9443645 0.869 rs10943609 chr6:79676328 A/T cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.56e-6 Intelligence (multi-trait analysis); TGCT cis rs4631830 0.900 rs10763576 chr10:51538813 A/T cg10326726 chr10:51549505 MSMB -0.25 -5.05 -0.41 1.51e-6 Prostate-specific antigen levels; TGCT cis rs56104184 1.000 rs56104184 chr19:49370310 C/T cg21252483 chr19:49399788 TULP2 -0.33 -5.2 -0.42 7.94e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs7000551 0.532 rs4872486 chr8:22256359 G/T cg12081754 chr8:22256438 SLC39A14 0.36 5.32 0.43 4.7e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9486715 0.867 rs2475025 chr6:96988696 A/T cg06623918 chr6:96969491 KIAA0776 -1.09 -15.75 -0.82 2.31e-31 Headache; TGCT cis rs682748 0.904 rs297170 chr5:17151417 T/C cg23987134 chr5:17158319 LOC285696 -0.23 -5.42 -0.44 2.93e-7 Hippocampal atrophy; TGCT cis rs11578119 1.000 rs12120764 chr1:170514229 G/A cg09767346 chr1:170501363 GORAB 0.65 5.17 0.42 9.21e-7 Male-pattern baldness; TGCT cis rs72634258 0.519 rs4908708 chr1:7938113 G/C cg26816564 chr1:7831052 VAMP3 0.57 4.51 0.38 1.46e-5 Inflammatory bowel disease; TGCT cis rs394563 0.559 rs7753269 chr6:149671360 G/A cg03678062 chr6:149772716 ZC3H12D 0.38 4.83 0.4 3.94e-6 Dupuytren's disease; TGCT cis rs477895 0.713 rs11600867 chr11:63972052 T/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 6.38 0.5 3.12e-9 Mean platelet volume; TGCT cis rs826838 1.000 rs9795768 chr12:39012479 T/C cg26384229 chr12:38710491 ALG10B 1.02 9.78 0.66 4.37e-17 Heart rate; TGCT cis rs7267979 1.000 rs11087520 chr20:25436827 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs10203711 0.933 rs4994752 chr2:239567309 C/A cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9486719 1.000 rs6923212 chr6:97061940 A/G cg06623918 chr6:96969491 KIAA0776 -0.95 -8.2 -0.59 2.62e-13 Migraine;Coronary artery disease; TGCT cis rs6967414 1.000 rs6967414 chr7:6749758 G/A cg09896999 chr7:6746977 ZNF12 -0.55 -6.34 -0.49 3.97e-9 Hematocrit;Hemoglobin concentration; TGCT trans rs4919669 0.668 rs10883761 chr10:104420018 A/G cg16267304 chr21:44985357 HSF2BP 0.65 6.69 0.51 6.85e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs2580764 0.678 rs2588521 chr2:55203931 C/G cg09592903 chr2:55203963 RTN4 0.24 5.4 0.44 3.29e-7 Mean platelet volume; TGCT cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg16325326 chr1:53192061 ZYG11B 0.69 8.18 0.59 2.93e-13 Monocyte count; TGCT cis rs3741404 0.895 rs1860368 chr11:63994692 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 -0.9 -9.87 -0.66 2.64e-17 Platelet count; TGCT cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs4595586 0.545 rs7307303 chr12:39368976 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7267979 1.000 rs2424710 chr20:25283886 C/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg06873352 chr17:61820015 STRADA -0.47 -5.12 -0.42 1.14e-6 Prudent dietary pattern; TGCT cis rs28595532 0.925 rs56200441 chr4:119497440 T/G cg21605333 chr4:119757512 SEC24D 1.33 8.01 0.58 7.07e-13 Cannabis dependence symptom count; TGCT cis rs769267 1.000 rs8103197 chr19:19443466 C/T cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs514406 0.644 rs4926928 chr1:53210163 G/T cg08736216 chr1:53307985 ZYG11A -0.24 -4.55 -0.38 1.24e-5 Monocyte count; TGCT cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -8.37 -0.6 1.03e-13 Platelet count; TGCT cis rs4919694 1.000 rs35159404 chr10:104805610 C/A cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs58722170 0.517 rs17559337 chr1:38039034 T/C cg17933807 chr1:38061675 GNL2 -0.83 -7.46 -0.56 1.32e-11 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6430585 0.591 rs12477421 chr2:136433740 A/G cg07169764 chr2:136633963 MCM6 1.07 9.6 0.65 1.19e-16 Corneal structure; TGCT cis rs2236918 0.710 rs851781 chr1:242034868 C/T cg04158730 chr1:242011433 EXO1 0.56 5.16 0.42 9.55e-7 Menopause (age at onset); TGCT cis rs1670533 1.000 rs935972 chr4:1045171 A/G cg20887711 chr4:1340912 KIAA1530 0.72 5.22 0.42 7.33e-7 Recombination rate (females); TGCT cis rs2637266 1.000 rs10219021 chr10:78364516 C/T cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs11098499 0.657 rs7664458 chr4:120371967 A/G cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs9325144 0.647 rs35138700 chr12:38804474 C/T cg26384229 chr12:38710491 ALG10B -0.61 -5.72 -0.46 7.51e-8 Morning vs. evening chronotype; TGCT cis rs2832191 0.716 rs1888440 chr21:30454484 C/T cg24692254 chr21:30365293 RNF160 0.98 11.36 0.71 6.16e-21 Dental caries; TGCT trans rs2727020 0.688 rs4929894 chr11:49196333 G/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.06 -0.59 5.53e-13 Coronary artery disease; TGCT cis rs8050907 0.744 rs11862204 chr16:4519586 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs7017914 0.905 rs2639955 chr8:71925342 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg13342137 chr4:2252803 MXD4 -0.17 -4.6 -0.38 1.05e-5 Obesity-related traits; TGCT cis rs2469997 0.800 rs2447177 chr8:120356431 A/G cg00681363 chr8:120844660 TAF2 0.72 4.69 0.39 7.2e-6 Hypertension (SNP x SNP interaction); TGCT cis rs12791968 0.765 rs2279359 chr11:44999605 A/G cg11846598 chr11:44996168 LOC221122 0.31 5.02 0.41 1.73e-6 Inhibitory control; TGCT cis rs7044106 0.791 rs10739572 chr9:123489815 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.45 5.16 0.42 9.67e-7 Hip circumference adjusted for BMI; TGCT cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs7100689 0.622 rs10749595 chr10:82172975 C/T cg01528321 chr10:82214614 TSPAN14 0.94 9.82 0.66 3.45e-17 Post bronchodilator FEV1; TGCT cis rs2658782 1.000 rs2658782 chr11:93166731 T/G cg15737290 chr11:93063684 CCDC67 0.79 5.61 0.45 1.24e-7 Pulmonary function decline; TGCT cis rs12893668 0.542 rs12884809 chr14:104095320 G/A cg26031613 chr14:104095156 KLC1 -0.58 -5.01 -0.41 1.8e-6 Reticulocyte count; TGCT cis rs12477438 0.501 rs12619780 chr2:99707307 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.81 7.89 0.58 1.34e-12 Chronic sinus infection; TGCT cis rs2354432 0.607 rs7516430 chr1:146767062 A/G cg25205988 chr1:146714368 CHD1L -1.18 -7.03 -0.53 1.24e-10 Mitochondrial DNA levels; TGCT cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.46 4.87 0.4 3.39e-6 Menopause (age at onset); TGCT cis rs12541335 0.639 rs3923433 chr8:22169798 A/T cg02463440 chr8:22132932 PIWIL2 0.26 5.16 0.42 9.37e-7 Hypertriglyceridemia; TGCT cis rs4689388 0.853 rs11729672 chr4:6293838 A/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs459571 0.959 rs416390 chr9:136908549 C/G cg14405625 chr9:136855902 VAV2 0.29 4.45 0.37 1.92e-5 Platelet distribution width; TGCT cis rs35883536 0.647 rs7524322 chr1:101047730 C/G cg06223162 chr1:101003688 GPR88 0.42 7.76 0.57 2.65e-12 Monocyte count; TGCT cis rs5769765 1.000 rs5770728 chr22:50259984 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.01 -0.47 1.96e-8 Schizophrenia; TGCT cis rs2640806 0.506 rs13254991 chr8:97371686 T/C cg04026948 chr8:97953330 PGCP -0.25 -4.55 -0.38 1.27e-5 Obesity-related traits; TGCT cis rs12477438 0.520 rs2516827 chr2:99772565 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs1008375 1.000 rs6854733 chr4:17640526 C/T cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12681287 0.752 rs10085920 chr8:87252666 C/T cg27223183 chr8:87520930 FAM82B -0.81 -5.64 -0.45 1.09e-7 Caudate activity during reward; TGCT cis rs2070488 0.775 rs6599208 chr3:38558104 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.89 -0.53 2.46e-10 Electrocardiographic conduction measures; TGCT cis rs3820068 0.559 rs6675334 chr1:15923580 A/T cg05660106 chr1:15850417 CASP9 0.8 8.18 0.59 2.86e-13 Systolic blood pressure; TGCT cis rs2070488 0.965 rs1870915 chr3:38494228 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.95 10.55 0.69 5.82e-19 Electrocardiographic conduction measures; TGCT cis rs3099143 1.000 rs3099134 chr15:77133168 T/G cg21673338 chr15:77095150 SCAPER -0.54 -5.15 -0.42 1.01e-6 Recalcitrant atopic dermatitis; TGCT cis rs35883536 0.528 rs10783138 chr1:101031061 C/T cg06223162 chr1:101003688 GPR88 0.43 8.41 0.6 8.23e-14 Monocyte count; TGCT cis rs6831352 0.959 rs6532796 chr4:100042242 C/T cg12011299 chr4:100065546 ADH4 -0.48 -5.72 -0.46 7.68e-8 Alcohol dependence; TGCT cis rs4788439 0.901 rs72770501 chr16:24982324 G/C cg07626409 chr16:25250191 ZKSCAN2 0.33 4.58 0.38 1.1e-5 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs8013055 0.846 rs10147392 chr14:105978537 T/G cg19700328 chr14:106028568 NA -0.53 -5.85 -0.47 4.1e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs2204008 0.744 rs8189486 chr12:38244968 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.42 0.55 1.6e-11 Bladder cancer; TGCT cis rs11098499 0.954 rs7437420 chr4:120312903 A/G cg09307838 chr4:120376055 NA 0.66 6.35 0.5 3.66e-9 Corneal astigmatism; TGCT cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg03806693 chr22:41940476 POLR3H 1.14 12.74 0.75 2.72e-24 Vitiligo; TGCT cis rs3947 0.951 rs1692813 chr8:11704296 G/T cg02840367 chr8:11660030 FDFT1 0.89 6.47 0.5 2e-9 Blood protein levels; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg11905131 chr22:24372483 LOC391322 0.7 5.63 0.45 1.14e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs11696501 0.688 rs6073855 chr20:44309670 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs1570884 0.516 rs7334387 chr13:50172133 T/A cg08779649 chr13:50194554 NA 0.37 5.84 0.46 4.24e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT trans rs1496653 0.602 rs13087238 chr3:23380071 C/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2832191 0.626 rs2254796 chr21:30341891 A/G cg24692254 chr21:30365293 RNF160 -0.93 -10.77 -0.7 1.69e-19 Dental caries; TGCT cis rs9291683 0.551 rs2240720 chr4:10020480 C/T cg00071950 chr4:10020882 SLC2A9 0.72 9.86 0.66 2.78e-17 Bone mineral density; TGCT cis rs3008870 1.000 rs2985824 chr1:67410171 C/T cg08660285 chr1:67390436 MIER1;WDR78 -1.04 -11.07 -0.71 3.1e-20 Lymphocyte percentage of white cells; TGCT cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg06481639 chr22:41940642 POLR3H 0.72 6.4 0.5 2.96e-9 Vitiligo; TGCT cis rs7552404 0.691 rs5745449 chr1:76344711 A/T cg03433033 chr1:76189801 ACADM -0.76 -7.76 -0.57 2.66e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1008375 1.000 rs2315561 chr4:17679695 C/T cg10189774 chr4:17578691 LAP3 0.56 5.25 0.43 6.39e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Vitiligo; TGCT cis rs13326165 0.760 rs11707931 chr3:52358417 C/G cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT trans rs3780486 0.846 rs913214 chr9:33135085 G/A cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT cis rs6430585 0.527 rs62168792 chr2:136415217 A/G cg07169764 chr2:136633963 MCM6 0.96 8.46 0.61 6.24e-14 Corneal structure; TGCT cis rs780096 0.545 rs11695549 chr2:27586155 A/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.38 4.89 0.4 3.06e-6 Total body bone mineral density; TGCT cis rs7666738 0.830 rs28516388 chr4:98987449 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs17125944 0.505 rs77137752 chr14:53230496 G/T cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs11105298 0.891 rs10858871 chr12:89871613 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg21724239 chr8:58056113 NA 0.52 5.47 0.44 2.37e-7 Developmental language disorder (linguistic errors); TGCT cis rs9640161 0.789 rs13223702 chr7:150058968 G/A cg10018233 chr7:150070692 REPIN1 0.31 4.45 0.37 1.88e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs4851254 0.550 rs13402289 chr2:100659389 C/T cg07810366 chr2:100720526 AFF3 -0.46 -4.91 -0.4 2.76e-6 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs115853212 chr4:119765354 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg22166914 chr1:53195759 ZYG11B 0.35 5.78 0.46 5.7e-8 Monocyte count; TGCT cis rs523522 0.847 rs11065132 chr12:120908459 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.58 0.51 1.19e-9 High light scatter reticulocyte count; TGCT cis rs2688608 0.653 rs12775558 chr10:75570868 G/A cg23231163 chr10:75533350 FUT11 -0.28 -4.79 -0.4 4.71e-6 Inflammatory bowel disease; TGCT cis rs9916302 0.718 rs7219909 chr17:37706243 C/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2456568 0.867 rs72962810 chr11:93663619 A/G cg16099599 chr11:93583650 C11orf90 -0.38 -4.51 -0.38 1.47e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs716804 0.678 rs10770096 chr11:10178359 C/G cg17061862 chr11:9590431 NA -0.37 -4.89 -0.4 3.06e-6 Neuroticism; TGCT cis rs9810089 0.802 rs73222302 chr3:136098085 A/G cg12473912 chr3:136751656 NA 0.35 4.98 0.41 2.11e-6 Gestational age at birth (child effect); TGCT cis rs2839186 0.560 rs9975345 chr21:47843004 T/C cg12379764 chr21:47803548 PCNT 0.53 5.87 0.47 3.75e-8 Testicular germ cell tumor; TGCT trans rs8073060 0.586 rs225265 chr17:33961972 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT trans rs2970818 0.831 rs10849086 chr12:4645400 G/A cg16313944 chr11:67775857 ALDH3B1 0.34 6.76 0.52 4.8e-10 Phosphorus levels; TGCT cis rs6663390 0.510 rs3754170 chr1:208087296 A/G cg03990033 chr1:208084030 CD34 0.57 4.94 0.41 2.45e-6 Facial morphology (factor 18); TGCT cis rs2840044 1.000 rs225295 chr17:33925755 A/G cg05299278 chr17:33885742 SLFN14 0.23 5.05 0.41 1.53e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs35146811 0.735 rs6948729 chr7:99787372 A/G cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs2836974 0.966 rs7283516 chr21:40690537 A/G cg11890956 chr21:40555474 PSMG1 1.13 11.5 0.72 2.86e-21 Cognitive function; TGCT cis rs13191362 0.935 rs34347104 chr6:163055716 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.86 0.52 2.88e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs35771425 1.000 rs12569232 chr1:211553064 G/C cg25617285 chr1:211431773 RCOR3 -0.5 -4.49 -0.37 1.63e-5 Educational attainment (years of education); TGCT cis rs3733346 0.553 rs2290403 chr4:942006 G/A cg22718636 chr4:961658 DGKQ 0.46 4.55 0.38 1.24e-5 Sjögren's syndrome; TGCT cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg15659132 chr6:26577336 NA 0.86 11.1 0.71 2.67e-20 Intelligence (multi-trait analysis); TGCT cis rs709400 0.567 rs28496120 chr14:103897899 C/T cg12935359 chr14:103987150 CKB -0.33 -4.96 -0.41 2.27e-6 Body mass index; TGCT cis rs17433780 0.504 rs6428494 chr1:89472196 C/T cg09516651 chr1:89888402 LOC400759 0.24 5.13 0.42 1.1e-6 Carotid intima media thickness; TGCT cis rs9733 0.544 rs72700902 chr1:150633347 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.28e-17 Electroencephalogram traits; TGCT cis rs6860806 0.531 rs2631359 chr5:131707892 C/T cg24060327 chr5:131705240 SLC22A5 0.78 8.46 0.61 6.22e-14 Breast cancer; TGCT cis rs11690935 0.959 rs11904009 chr2:172627343 T/G cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs12549902 0.966 rs4737000 chr8:41509727 A/C cg21772509 chr8:41503840 NKX6-3 0.87 10.06 0.67 9.27e-18 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs6545883 0.783 rs12713442 chr2:61848078 G/A cg15711740 chr2:61764176 XPO1 -0.58 -5.31 -0.43 4.79e-7 Tuberculosis; TGCT cis rs8062405 0.929 rs11150609 chr16:28870596 A/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs295140 0.566 rs295141 chr2:201163556 C/T cg23649088 chr2:200775458 C2orf69 -0.29 -4.65 -0.39 8.34e-6 QT interval; TGCT cis rs11783469 0.522 rs4872125 chr8:23268270 G/A cg00472375 chr8:23315376 ENTPD4 0.68 5.3 0.43 5.01e-7 Reticulocyte count; TGCT cis rs644148 0.836 rs2686777 chr19:45000386 T/C cg15540054 chr19:45004280 ZNF180 -0.66 -5.34 -0.43 4.23e-7 Personality dimensions; TGCT cis rs2067615 0.579 rs4964489 chr12:107171808 A/G cg15890332 chr12:107067104 RFX4 0.28 5.57 0.45 1.47e-7 Heart rate; TGCT cis rs6901250 0.851 rs339360 chr6:117160872 G/T cg12892004 chr6:117198278 RFX6 -0.54 -6.65 -0.51 8.24e-10 C-reactive protein levels; TGCT cis rs4665809 0.941 rs11126336 chr2:26245931 C/T cg25036284 chr2:26402008 FAM59B -0.57 -5.03 -0.41 1.65e-6 Gut microbiome composition (summer); TGCT cis rs9677476 0.516 rs2303349 chr2:232030861 A/G cg27665808 chr2:232055229 NA 0.36 4.51 0.38 1.48e-5 Food antigen IgG levels; TGCT cis rs10992471 0.756 rs10123342 chr9:95087824 T/G cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.25 -0.49 6.14e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.82e-6 Obesity-related traits; TGCT cis rs198813 0.611 rs198823 chr6:26122933 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.62 -5.27 -0.43 5.94e-7 Intelligence (multi-trait analysis); TGCT cis rs4455778 0.657 rs10233258 chr7:49003132 T/A cg26309511 chr7:48887640 NA -0.5 -6.02 -0.48 1.87e-8 Lung cancer in never smokers; TGCT cis rs10927875 0.864 rs12135073 chr1:16167799 C/T cg14742211 chr1:16348397 CLCNKA 0.18 4.55 0.38 1.26e-5 Dilated cardiomyopathy; TGCT cis rs2562456 0.837 rs62110205 chr19:21760071 A/G cg25650185 chr19:21324782 ZNF431 -0.64 -5.2 -0.42 8.11e-7 Pain; TGCT cis rs208520 0.955 rs208532 chr6:66961280 T/A cg07460842 chr6:66804631 NA -0.83 -7.52 -0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs7412746 0.658 rs6658066 chr1:150918937 T/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs524023 1.000 rs10897518 chr11:64360705 A/G cg07733098 chr11:64478343 NRXN2 -0.3 -4.51 -0.38 1.48e-5 Urate levels in obese individuals; TGCT cis rs4654899 0.865 rs1472831 chr1:21435940 C/T cg01072550 chr1:21505969 NA -0.47 -7.09 -0.54 8.92e-11 Superior frontal gyrus grey matter volume; TGCT cis rs9921338 0.961 rs56136462 chr16:11415595 A/G cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9303401 0.659 rs62083436 chr17:57031742 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs1129187 0.702 rs2296805 chr6:42928758 T/G cg17345569 chr6:42928274 GNMT -0.51 -5.15 -0.42 9.82e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10782582 0.593 rs12131344 chr1:76136437 C/T cg10523679 chr1:76189770 ACADM -0.72 -7.19 -0.54 5.48e-11 Daytime sleep phenotypes; TGCT cis rs1218582 0.772 rs4845688 chr1:154884142 T/C cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs58722170 0.627 rs12046650 chr1:38082123 C/T cg17933807 chr1:38061675 GNL2 -0.86 -8.69 -0.62 1.83e-14 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7666738 0.830 rs34890015 chr4:99023769 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.62 0.56 5.53e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7809950 0.678 rs17153981 chr7:106922106 A/G cg23024343 chr7:107201750 COG5 -0.43 -5.88 -0.47 3.51e-8 Coronary artery disease; TGCT cis rs9926296 0.568 rs7203907 chr16:89833774 C/G cg21285383 chr16:89894308 SPIRE2 0.43 6.85 0.52 3e-10 Vitiligo; TGCT cis rs2012796 0.743 rs8020575 chr14:81859521 G/A cg02996355 chr14:81879375 NA 0.56 5.45 0.44 2.66e-7 Night sleep phenotypes; TGCT cis rs4862750 0.872 rs4862748 chr4:187877388 C/T cg11301795 chr4:187892539 NA 0.38 5.58 0.45 1.47e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6087990 0.735 rs4911260 chr20:31376490 T/C cg13636640 chr20:31349939 DNMT3B 0.95 12.38 0.74 2.06e-23 Ulcerative colitis; TGCT cis rs9467711 0.606 rs12174639 chr6:26373121 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7043114 0.507 rs10820971 chr9:95161740 G/C cg14631576 chr9:95140430 CENPP -0.29 -4.79 -0.39 4.76e-6 Height; TGCT cis rs9303401 0.659 rs62081316 chr17:56781499 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs35306767 0.951 rs61833265 chr10:990143 C/T cg20503657 chr10:835505 NA 0.63 8.32 0.6 1.37e-13 Eosinophil percentage of granulocytes; TGCT cis rs2576037 0.583 rs504668 chr18:44410749 T/C cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs3617 0.573 rs9825230 chr3:52901974 G/A cg10802521 chr3:52805072 NEK4 -0.54 -6.05 -0.48 1.61e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9653442 0.564 rs10185510 chr2:100790581 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.4 -0.44 3.2e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11122272 0.735 rs2437149 chr1:231490105 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.65 -0.51 8.43e-10 Hemoglobin concentration; TGCT cis rs9303401 0.614 rs62084387 chr17:57148027 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.81 0.46 4.99e-8 Cognitive test performance; TGCT cis rs8072100 0.570 rs9905073 chr17:45468296 G/A cg08085267 chr17:45401833 C17orf57 -0.52 -5.68 -0.45 8.95e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6912958 0.967 rs9450688 chr6:88159276 T/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.74 -0.39 5.79e-6 Monocyte percentage of white cells; TGCT cis rs4273100 1.000 rs12602286 chr17:19236954 G/T cg01534423 chr17:18965556 NA -0.95 -5.98 -0.47 2.2e-8 Schizophrenia; TGCT cis rs12541335 0.579 rs59283125 chr8:22212311 G/A cg07298985 chr8:22133076 PIWIL2 0.34 5.18 0.42 8.75e-7 Hypertriglyceridemia; TGCT cis rs17102423 0.602 rs1007914 chr14:65566261 C/A cg11161011 chr14:65562177 MAX -0.54 -7.71 -0.57 3.57e-12 Obesity-related traits; TGCT cis rs6964587 0.967 rs10231350 chr7:91808499 G/T cg17063962 chr7:91808500 NA 0.91 9.88 0.66 2.51e-17 Breast cancer; TGCT cis rs9810089 0.934 rs570621 chr3:136000743 A/G cg12473912 chr3:136751656 NA 0.35 4.91 0.4 2.77e-6 Gestational age at birth (child effect); TGCT cis rs2742234 0.915 rs2742233 chr10:43610558 C/T cg02780029 chr10:43622663 RET -0.25 -4.84 -0.4 3.81e-6 Hirschsprung disease; TGCT cis rs3935685 1.000 rs4886904 chr15:78027178 C/T cg03457338 chr15:78040120 NA -0.23 -5.38 -0.44 3.54e-7 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.545 rs1821826 chr2:100764711 C/T cg22139774 chr2:100720529 AFF3 -0.37 -5.95 -0.47 2.54e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs734999 0.588 rs2843401 chr1:2528133 T/C cg18854424 chr1:2615690 NA -0.46 -5.23 -0.43 6.92e-7 Ulcerative colitis; TGCT cis rs1857353 0.708 rs2040081 chr1:75906765 T/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs1997103 0.954 rs9649854 chr7:55410213 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs17253792 0.822 rs77555779 chr14:56078430 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs36051895 0.632 rs62541958 chr9:5175621 T/C cg02405213 chr9:5042618 JAK2 -0.72 -9.73 -0.66 5.69e-17 Pediatric autoimmune diseases; TGCT cis rs2933343 0.621 rs789249 chr3:128578453 T/C cg11901034 chr3:128598214 ACAD9 -0.64 -6.16 -0.48 9.37e-9 IgG glycosylation; TGCT cis rs910316 0.726 rs12882664 chr14:75446778 C/T cg08847533 chr14:75593920 NEK9 0.83 8.78 0.62 1.1e-14 Height; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg23131131 chr22:24373011 LOC391322 0.81 8.72 0.62 1.53e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs910316 1.000 rs9805979 chr14:75566209 G/A cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs7914558 1.000 rs7899084 chr10:104872547 A/T cg15744005 chr10:104629667 AS3MT -0.42 -5.21 -0.42 7.57e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12765878 1.000 rs10883942 chr10:105651386 A/G cg11005552 chr10:105648138 OBFC1 0.44 7.66 0.57 4.54e-12 Coronary artery disease; TGCT cis rs733175 0.857 rs10018663 chr4:10004797 C/T cg00071950 chr4:10020882 SLC2A9 0.55 4.45 0.37 1.85e-5 Psychosis and Alzheimer's disease; TGCT cis rs4780401 0.573 rs8045673 chr16:11804385 C/A cg01061890 chr16:11836724 TXNDC11 -0.6 -5.71 -0.46 7.74e-8 Rheumatoid arthritis; TGCT cis rs9818758 0.607 rs13068038 chr3:49294250 C/A cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6988636 0.901 rs2602001 chr8:124195974 T/C cg27053337 chr8:124217698 FAM83A -0.55 -4.55 -0.38 1.25e-5 Urinary uromodulin levels; TGCT cis rs7523273 0.606 rs2724380 chr1:207949682 C/T cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs734999 0.967 rs4486391 chr1:2513055 A/T cg18854424 chr1:2615690 NA 0.46 5.84 0.46 4.32e-8 Ulcerative colitis; TGCT cis rs72615157 0.664 rs6953580 chr7:99825275 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.64 5.04 0.41 1.63e-6 Lung function (FEV1/FVC); TGCT cis rs13394619 0.935 rs12468019 chr2:11725049 T/C cg07314298 chr2:11723111 GREB1 -0.29 -5.14 -0.42 1.05e-6 Endometriosis; TGCT cis rs6088580 0.634 rs6088475 chr20:32964987 T/C cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs10791323 0.569 rs2187450 chr11:133743792 A/G cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs17076896 0.708 rs61956078 chr13:19932579 C/T cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT trans rs10203711 1.000 rs12692239 chr2:239553947 T/C cg16021909 chr1:248021091 TRIM58 -0.68 -6.93 -0.53 2.04e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6426558 0.514 rs3754418 chr1:227348473 T/C cg10327440 chr1:227177885 CDC42BPA -0.6 -7.22 -0.54 4.62e-11 Neutrophil percentage of white cells; TGCT cis rs3796352 1.000 rs59583591 chr3:53119581 T/C cg07884673 chr3:53033167 SFMBT1 0.49 5.11 0.42 1.16e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7223966 1.000 rs8068603 chr17:61755211 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.05 0.41 1.51e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs6500602 0.647 rs4786501 chr16:4536165 G/T cg12031863 chr16:4587854 C16orf5 0.29 4.7 0.39 6.91e-6 Schizophrenia; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs624899 0.522 rs645584 chr19:11612466 A/G cg14128973 chr19:11649462 CNN1 0.45 6.22 0.49 7.14e-9 Presence of antiphospholipid antibodies; TGCT cis rs9527 0.590 rs11191540 chr10:104822809 G/C cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs12210905 1.000 rs9368498 chr6:27254006 G/A cg08851530 chr6:28072375 NA 1.29 5.49 0.44 2.19e-7 Hip circumference adjusted for BMI; TGCT cis rs7103648 0.897 rs35032070 chr11:47408592 G/A cg20307385 chr11:47447363 PSMC3 1.03 12.12 0.74 8.55e-23 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs4819052 0.819 rs13046807 chr21:46672286 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.7 0.39 6.83e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs875971 0.658 rs432667 chr7:65514633 A/G cg11764359 chr7:65958608 NA 0.54 4.66 0.39 7.88e-6 Aortic root size; TGCT cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs597539 0.652 rs584108 chr11:68630282 A/T cg21963583 chr11:68658836 MRPL21 -0.34 -5.74 -0.46 6.87e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs344364 0.511 rs1657133 chr16:1950300 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7552167 0.925 rs11249021 chr1:24512881 G/T cg01960748 chr1:24522592 NA -0.44 -5.01 -0.41 1.87e-6 Psoriasis vulgaris; TGCT cis rs9291683 0.588 rs6844329 chr4:10018544 T/C cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Bone mineral density; TGCT cis rs3008870 0.755 rs4486425 chr1:67460791 T/C cg08660285 chr1:67390436 MIER1;WDR78 -0.82 -8.51 -0.61 4.75e-14 Lymphocyte percentage of white cells; TGCT cis rs780096 0.545 rs6716894 chr2:27583273 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.38 4.88 0.4 3.18e-6 Total body bone mineral density; TGCT cis rs10782582 0.593 rs11164042 chr1:76178440 G/A cg22875332 chr1:76189707 ACADM -0.56 -6.37 -0.5 3.39e-9 Daytime sleep phenotypes; TGCT cis rs4970988 0.607 rs7548516 chr1:150980281 C/T cg13201342 chr1:150782303 ARNT;CTSK -0.27 -4.68 -0.39 7.39e-6 Urate levels; TGCT cis rs9372253 0.934 rs9320327 chr6:110715194 T/A cg13266496 chr6:110720918 DDO -0.46 -5.68 -0.45 9.19e-8 Platelet distribution width; TGCT cis rs7666738 0.515 rs13434650 chr4:98889886 A/G cg05340658 chr4:99064831 C4orf37 0.57 6.06 0.48 1.48e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs880470 chr4:98922522 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs778371 0.723 rs35491427 chr2:233688542 C/T cg08000102 chr2:233561755 GIGYF2 -0.67 -7.64 -0.57 5.21e-12 Schizophrenia; TGCT cis rs597539 0.616 rs513476 chr11:68698996 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 7.43 0.55 1.56e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7267979 1.000 rs2500424 chr20:25391969 C/T cg03522245 chr20:25566470 NINL -0.63 -6.79 -0.52 4.05e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg18110333 chr6:292329 DUSP22 -0.72 -7.76 -0.57 2.71e-12 Menopause (age at onset); TGCT cis rs2836950 0.545 rs2836952 chr21:40616651 G/C cg11644478 chr21:40555479 PSMG1 -0.53 -4.91 -0.4 2.81e-6 Menarche (age at onset); TGCT cis rs9341808 0.600 rs2505930 chr6:80837058 A/G cg08355045 chr6:80787529 NA 0.34 5.42 0.44 2.95e-7 Sitting height ratio; TGCT cis rs61931739 0.500 rs11053199 chr12:34450534 C/T cg06521331 chr12:34319734 NA 0.27 4.56 0.38 1.19e-5 Morning vs. evening chronotype; TGCT cis rs7223966 1.000 rs11658329 chr17:61763031 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.64 -5.29 -0.43 5.35e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2153535 0.560 rs9379214 chr6:8480870 T/C cg23788917 chr6:8435910 SLC35B3 0.64 5.82 0.46 4.65e-8 Motion sickness; TGCT cis rs17376456 0.569 rs11948511 chr5:93286601 A/C cg25358565 chr5:93447407 FAM172A -0.62 -5.85 -0.47 4.08e-8 Diabetic retinopathy; TGCT cis rs12580194 1.000 rs12579030 chr12:55689194 T/C cg20672549 chr12:56432144 IKZF4 0.27 4.75 0.39 5.55e-6 Cancer; TGCT cis rs9640161 0.830 rs3757423 chr7:150067714 A/G cg21361702 chr7:150065534 REPIN1 -0.48 -4.54 -0.38 1.29e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2836974 0.931 rs13047663 chr21:40708818 C/T cg11890956 chr21:40555474 PSMG1 1.03 9.6 0.65 1.17e-16 Cognitive function; TGCT cis rs4700695 0.841 rs152935 chr5:65358593 A/G cg21114390 chr5:65439923 SFRS12 -0.6 -4.46 -0.37 1.79e-5 Facial morphology (factor 19); TGCT cis rs1838472 0.607 rs9844005 chr3:123979763 G/A cg19008133 chr3:123124015 ADCY5 -0.18 -4.58 -0.38 1.12e-5 Schizophrenia; TGCT cis rs1059312 0.500 rs12303338 chr12:129276641 C/T cg09035930 chr12:129282057 SLC15A4 -0.49 -7.24 -0.55 4.12e-11 Systemic lupus erythematosus; TGCT cis rs477895 1.000 rs66968227 chr11:64070930 T/C cg23719950 chr11:63933701 MACROD1 -0.59 -4.66 -0.39 8.19e-6 Mean platelet volume; TGCT cis rs10510102 0.808 rs7920024 chr10:123703578 G/T cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs1552244 0.554 rs3732965 chr3:10048760 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs2742417 0.603 rs1468542 chr3:45779136 A/T cg04837898 chr3:45731254 SACM1L 0.67 7.3 0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs12220238 0.841 rs10824161 chr10:76133762 C/G cg19889307 chr10:75911429 ADK;AP3M1 -0.9 -6.35 -0.5 3.66e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3617 0.573 rs62253582 chr3:52928333 G/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.67 -0.39 7.82e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs950776 0.620 rs7181405 chr15:78948152 A/G cg03762349 chr15:79060523 ADAMTS7 0.24 4.91 0.4 2.82e-6 Sudden cardiac arrest; TGCT cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg08048268 chr3:133502702 NA 0.53 7.22 0.54 4.55e-11 Iron status biomarkers; TGCT cis rs1048238 0.548 rs848217 chr1:16272250 A/G cg21385522 chr1:16154831 NA -0.66 -8.24 -0.59 2.05e-13 Systolic blood pressure; TGCT cis rs2742417 0.967 rs1534875 chr3:45741043 T/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT trans rs208520 0.507 rs9453585 chr6:66796668 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.1 -16.96 -0.84 4.22e-34 Exhaled nitric oxide output; TGCT cis rs9926296 0.618 rs8058179 chr16:89846987 C/T cg04287289 chr16:89883240 FANCA -0.67 -6.61 -0.51 1.01e-9 Vitiligo; TGCT cis rs6500602 0.592 rs28789232 chr16:4447552 C/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.1 0.42 1.26e-6 Schizophrenia; TGCT cis rs4819052 0.632 rs4819050 chr21:46692943 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.62 6.04 0.48 1.65e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11122272 0.735 rs2491405 chr1:231513431 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs9926296 0.712 rs447735 chr16:89734349 T/C cg26513180 chr16:89883248 FANCA -0.68 -6.38 -0.5 3.15e-9 Vitiligo; TGCT cis rs7091068 0.616 rs6583905 chr10:95504022 T/G cg20715218 chr10:95462985 C10orf4 0.52 4.62 0.38 9.33e-6 Urinary tract infection frequency; TGCT cis rs2115630 0.875 rs8039472 chr15:85361644 A/G cg17173187 chr15:85201210 NMB -0.49 -5.9 -0.47 3.2e-8 P wave terminal force; TGCT cis rs6547741 0.752 rs7562863 chr2:27892694 T/A cg27432699 chr2:27873401 GPN1 -0.24 -6.15 -0.48 9.74e-9 Oral cavity cancer; TGCT cis rs6089829 0.962 rs2872543 chr20:61665017 G/A cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg18305652 chr10:134549665 INPP5A 0.35 5.69 0.45 8.83e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3741404 0.868 rs595880 chr11:64006466 T/G cg19570321 chr11:63258214 HRASLS5 -0.45 -5.18 -0.42 8.76e-7 Platelet count; TGCT cis rs2836950 0.520 rs11911087 chr21:40665192 G/A cg06238570 chr21:40685208 BRWD1 -0.61 -6.19 -0.49 7.89e-9 Menarche (age at onset); TGCT cis rs9916302 0.904 rs6503507 chr17:37525274 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs7086627 0.515 rs10887895 chr10:82210011 A/G cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs4372836 0.504 rs13024443 chr2:29046185 C/T cg09522027 chr2:28974177 PPP1CB -0.56 -5.68 -0.45 9.2e-8 Body mass index; TGCT cis rs7666738 0.830 rs7673880 chr4:99057262 A/G cg05340658 chr4:99064831 C4orf37 0.51 5.66 0.45 9.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12908161 1.000 rs35808647 chr15:85377441 G/A cg17173187 chr15:85201210 NMB 0.53 5.65 0.45 1.03e-7 Schizophrenia; TGCT trans rs10022799 0.836 rs28444899 chr4:168128646 T/G cg08507725 chr4:8239220 SH3TC1 0.34 7.03 0.53 1.23e-10 Cognitive function; TGCT cis rs4689388 0.926 rs4343789 chr4:6285228 C/G cg14416269 chr4:6271139 WFS1 0.39 5.25 0.43 6.47e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs629535 0.814 rs571682 chr8:70062793 A/G cg21567404 chr3:27674614 NA 0.52 7.95 0.58 9.59e-13 Dupuytren's disease; TGCT cis rs2276314 1.000 rs58054756 chr18:33554053 G/C cg19628046 chr18:33552617 C18orf21 0.52 4.46 0.37 1.8e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs6545883 0.772 rs1186709 chr2:61689380 G/A cg15711740 chr2:61764176 XPO1 -0.59 -5.39 -0.44 3.36e-7 Tuberculosis; TGCT cis rs9308731 1.000 rs7567444 chr2:111863438 T/C cg04202892 chr2:111875749 ACOXL 0.44 4.58 0.38 1.12e-5 Chronic lymphocytic leukemia; TGCT cis rs1153858 0.887 rs28569043 chr15:45730926 A/T cg26924012 chr15:45694286 SPATA5L1 0.99 12.56 0.75 7.42e-24 Homoarginine levels; TGCT cis rs9549260 0.564 rs9549271 chr13:41295477 T/C cg21288729 chr13:41239152 FOXO1 0.92 8.87 0.62 6.71e-15 Red blood cell count; TGCT cis rs2242116 0.932 rs1531137 chr3:46943028 T/C cg27129171 chr3:47204927 SETD2 0.61 6.15 0.48 9.79e-9 Birth weight; TGCT cis rs617219 0.698 rs7379187 chr5:78521354 T/C cg09550809 chr5:78407562 BHMT 0.39 5.63 0.45 1.12e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs922182 0.633 rs4776700 chr15:64270861 A/T cg02919090 chr15:64263738 DAPK2 -0.29 -5.21 -0.42 7.69e-7 Blood protein levels; TGCT cis rs12497850 0.931 rs9876848 chr3:48844059 G/A cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs72781680 0.846 rs55707417 chr2:24029928 G/A cg08917208 chr2:24149416 ATAD2B 0.93 5.84 0.46 4.22e-8 Lymphocyte counts; TGCT cis rs4963124 0.886 rs10902216 chr11:739392 G/C cg01741372 chr11:783889 NA 0.43 4.52 0.38 1.41e-5 Proteinuria and chronic kidney disease; TGCT cis rs2839186 0.933 rs56955294 chr21:47708953 A/G cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg17457637 chr7:27170717 HOXA4 -0.47 -4.95 -0.41 2.32e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg07424592 chr7:64974309 NA -1.27 -7.28 -0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs10256972 0.967 rs4723338 chr7:1036241 A/G cg16145915 chr7:1198662 ZFAND2A -0.38 -4.53 -0.38 1.35e-5 Longevity;Endometriosis; TGCT cis rs6882046 0.513 rs34316 chr5:88015545 A/C cg24804195 chr5:87968844 LOC645323 -0.6 -5.96 -0.47 2.4e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT trans rs13323436 1.000 rs13323436 chr3:85502845 A/T cg11225405 chr1:117038246 NA -0.65 -7.06 -0.54 1.05e-10 Visceral fat; TGCT cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs4642101 0.680 rs6442330 chr3:12820501 A/G cg05775895 chr3:12838266 CAND2 0.68 7.28 0.55 3.44e-11 QRS complex (12-leadsum); TGCT cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs4240897 0.935 rs3766744 chr1:12043717 G/A cg13216073 chr1:12042593 MFN2 0.2 5.89 0.47 3.32e-8 Tuberculosis; TGCT cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.04 -9.22 -0.64 9.69e-16 Platelet count; TGCT cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.89 0.4 3e-6 Platelet count; TGCT cis rs62283056 0.512 rs752854 chr4:6281961 C/T cg25554036 chr4:6271136 WFS1 0.53 6.84 0.52 3.27e-10 Cisplatin-induced ototoxicity; TGCT cis rs7666738 0.830 rs2865989 chr4:99067532 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10782582 0.593 rs1412717 chr1:76125471 C/T cg22875332 chr1:76189707 ACADM -0.54 -6.21 -0.49 7.36e-9 Daytime sleep phenotypes; TGCT cis rs3809566 0.637 rs8026047 chr15:63323347 C/G cg00520135 chr15:63333846 TPM1 0.45 4.59 0.38 1.07e-5 Platelet count; TGCT cis rs6089829 0.962 rs2277768 chr20:61666823 T/C cg02380750 chr20:61661411 NA 0.34 6.13 0.48 1.08e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs12681287 0.640 rs12549332 chr8:87353392 G/A cg27223183 chr8:87520930 FAM82B -0.9 -6.64 -0.51 8.93e-10 Caudate activity during reward; TGCT cis rs11190604 0.767 rs10883484 chr10:102174803 G/C cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1062177 1.000 rs2964584 chr5:151142878 T/C cg12924095 chr5:151150029 G3BP1 0.36 5.26 0.43 6.22e-7 Preschool internalizing problems; TGCT cis rs67478160 0.584 rs2295147 chr14:104195664 A/G cg01849466 chr14:104193079 ZFYVE21 0.19 4.55 0.38 1.24e-5 Schizophrenia; TGCT cis rs2070488 0.965 rs2154778 chr3:38553639 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.86 -8.57 -0.61 3.38e-14 Electrocardiographic conduction measures; TGCT cis rs4665809 0.878 rs6748745 chr2:26364190 C/T cg04944784 chr2:26401820 FAM59B -0.71 -6.24 -0.49 6.24e-9 Gut microbiome composition (summer); TGCT cis rs12681287 0.640 rs7833049 chr8:87445898 T/C cg27223183 chr8:87520930 FAM82B 0.89 6.43 0.5 2.54e-9 Caudate activity during reward; TGCT cis rs71435601 0.628 rs538928 chr2:21389019 C/T cg25035485 chr2:21266500 APOB -0.51 -4.46 -0.37 1.82e-5 Cholesterol, total; TGCT cis rs7267979 1.000 rs6107033 chr20:25363591 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs72945132 0.825 rs12287883 chr11:70122369 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs4919687 0.550 rs12259058 chr10:104484799 A/G cg05855489 chr10:104503620 C10orf26 0.56 4.51 0.38 1.5e-5 Colorectal cancer; TGCT cis rs7677751 0.806 rs4864863 chr4:55100831 A/G cg17187183 chr4:55093834 PDGFRA 0.56 7.13 0.54 7.37e-11 Corneal astigmatism; TGCT cis rs1801251 1.000 rs2305137 chr2:233712049 G/A cg08000102 chr2:233561755 GIGYF2 -0.63 -6.36 -0.5 3.55e-9 Coronary artery disease; TGCT cis rs12188164 0.965 rs41282625 chr5:475626 C/G cg26850624 chr5:429559 AHRR -0.21 -4.89 -0.4 3.01e-6 Cystic fibrosis severity; TGCT cis rs2735413 0.564 rs74864339 chr16:78095071 C/T cg09132178 chr16:78079569 NA 0.33 4.44 0.37 1.98e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs6570726 0.846 rs411468 chr6:145832792 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 0.841 rs115918392 chr4:119610356 T/A cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.66e-7 Cannabis dependence symptom count; TGCT cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg22535103 chr8:58192502 C8orf71 -0.4 -5.06 -0.41 1.44e-6 Developmental language disorder (linguistic errors); TGCT cis rs1153858 1.000 rs10519022 chr15:45663684 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -4.9 -0.4 2.97e-6 Homoarginine levels; TGCT cis rs12477438 0.520 rs13009147 chr2:99803998 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs6430585 0.583 rs12373779 chr2:136586840 A/C cg07169764 chr2:136633963 MCM6 1.17 11.08 0.71 2.99e-20 Corneal structure; TGCT cis rs7582180 0.715 rs7571306 chr2:100906084 G/C cg14675211 chr2:100938903 LONRF2 0.45 4.52 0.38 1.4e-5 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.699 rs7435196 chr4:9967556 A/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.62 -0.56 5.78e-12 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs3780486 0.957 rs10971434 chr9:33168891 C/A cg04842962 chr6:43655489 MRPS18A 1.15 11.06 0.7 3.24e-20 IgG glycosylation; TGCT cis rs6912958 0.559 rs499373 chr6:88042062 A/T cg04972856 chr6:88032051 C6orf162;GJB7 0.39 4.48 0.37 1.66e-5 Monocyte percentage of white cells; TGCT cis rs5769765 0.505 rs4561759 chr22:50256686 C/T cg22709217 chr22:50311962 ALG12;CRELD2 1.0 6.16 0.48 9.32e-9 Schizophrenia; TGCT cis rs6426558 0.537 rs6699828 chr1:227274591 T/C cg10327440 chr1:227177885 CDC42BPA 0.61 7.41 0.55 1.72e-11 Neutrophil percentage of white cells; TGCT cis rs902774 0.554 rs4503623 chr12:53353759 T/C cg16329197 chr12:53359506 NA -0.5 -7.02 -0.53 1.3e-10 Prostate cancer; TGCT cis rs7666738 0.546 rs34159897 chr4:98787367 T/C cg17366294 chr4:99064904 C4orf37 0.61 5.69 0.46 8.47e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.897 rs3733577 chr4:17649233 T/G cg18681998 chr4:17616180 MED28 1.05 12.0 0.73 1.69e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10540 1.000 rs71487296 chr11:500282 G/A cg03934478 chr11:495069 RNH1 0.37 6.0 0.47 2.03e-8 Body mass index; TGCT trans rs6089829 0.855 rs6090203 chr20:61663632 G/A cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs17173637 0.764 rs1044616 chr7:150502075 G/C cg06746365 chr7:151468796 PRKAG2 0.3 4.62 0.38 9.65e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs433598 0.514 rs16970500 chr16:20680152 A/C cg08248577 chr16:19727447 IQCK;C16orf88 -0.24 -4.71 -0.39 6.44e-6 Schizophrenia; TGCT cis rs9910055 0.530 rs2269907 chr17:42294215 G/A cg19774624 chr17:42201019 HDAC5 -0.71 -7.51 -0.56 9.96e-12 Total body bone mineral density; TGCT cis rs950169 0.887 rs220333 chr15:85091133 C/T cg11189052 chr15:85197271 WDR73 0.8 6.62 0.51 9.89e-10 Schizophrenia; TGCT cis rs7586879 0.929 rs6545808 chr2:25124388 C/A cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs4631830 0.896 rs7077830 chr10:51522276 C/G cg10326726 chr10:51549505 MSMB 0.22 4.49 0.37 1.62e-5 Prostate-specific antigen levels; TGCT cis rs6952808 0.609 rs6944877 chr7:1952582 T/G cg04267008 chr7:1944627 MAD1L1 -0.35 -4.53 -0.38 1.38e-5 Bipolar disorder and schizophrenia; TGCT cis rs533581 0.866 rs475796 chr16:88970776 C/G cg16701003 chr16:89028210 CBFA2T3 0.37 5.05 0.41 1.56e-6 Social autistic-like traits; TGCT cis rs7666738 0.578 rs1989109 chr4:98881246 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7216064 1.000 rs12602912 chr17:65870073 C/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7772486 0.875 rs6570736 chr6:146388320 C/T cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.747 rs57767914 chr20:61659108 C/G cg08045932 chr20:61659980 NA -0.31 -4.47 -0.37 1.76e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs4975709 0.589 rs4975747 chr5:1862836 G/A cg07747251 chr5:1868357 NA 0.38 5.52 0.44 1.92e-7 Cardiovascular disease risk factors; TGCT cis rs12210905 1.000 rs7756481 chr6:27115069 G/C cg08851530 chr6:28072375 NA 1.09 5.27 0.43 5.76e-7 Hip circumference adjusted for BMI; TGCT cis rs3020333 0.875 rs2982571 chr6:152012739 A/T cg22157087 chr6:152012887 ESR1 -0.19 -4.83 -0.4 3.91e-6 Total body bone mineral density; TGCT cis rs1018836 0.923 rs9643308 chr8:91625399 A/C cg16814680 chr8:91681699 NA -0.85 -9.22 -0.64 9.9e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9993613 1.000 rs4694504 chr4:73496691 A/G cg15102770 chr4:73434591 ADAMTS3 0.52 4.8 0.4 4.5e-6 Hip circumference adjusted for BMI;Height; TGCT trans rs561341 0.882 rs563539 chr17:30307958 A/G cg20587970 chr11:113659929 NA -1.03 -12.7 -0.75 3.52e-24 Hip circumference adjusted for BMI; TGCT cis rs709400 0.628 rs72708854 chr14:103864885 T/C cg12935359 chr14:103987150 CKB -0.36 -5.37 -0.43 3.67e-7 Body mass index; TGCT cis rs9468199 0.505 rs72847381 chr6:27873931 G/A cg08851530 chr6:28072375 NA 1.53 7.14 0.54 6.96e-11 Parkinson's disease; TGCT cis rs12451471 0.637 rs12950757 chr17:78096800 T/G cg06718696 chr17:78121285 EIF4A3 0.74 6.09 0.48 1.29e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs10791323 0.569 rs2282602 chr11:133714522 G/A cg15485101 chr11:133734466 NA 0.4 5.27 0.43 5.83e-7 Childhood ear infection; TGCT cis rs1018836 0.637 rs7843684 chr8:91470035 G/C cg16814680 chr8:91681699 NA -0.71 -7.27 -0.55 3.49e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs35146811 0.883 rs4134903 chr7:99711040 G/A cg22906224 chr7:99728672 NA 0.5 4.46 0.37 1.82e-5 Coronary artery disease; TGCT cis rs10946940 0.930 rs12215012 chr6:27507494 C/G cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.6 -0.38 1.04e-5 Systemic lupus erythematosus; TGCT cis rs67073037 0.915 rs12613887 chr2:29111099 T/C cg09522027 chr2:28974177 PPP1CB 0.63 4.96 0.41 2.23e-6 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs763014 0.931 rs2071982 chr16:630405 T/G cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs1371867 0.875 rs1788178 chr8:101332518 A/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs7572733 0.555 rs2164071 chr2:198915467 T/C cg00792783 chr2:198669748 PLCL1 0.59 5.15 0.42 1.01e-6 Dermatomyositis; TGCT cis rs2742417 1.000 rs2673051 chr3:45732409 G/T cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs10504229 0.683 rs72650849 chr8:58140323 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.962 rs13147921 chr4:99069296 C/G cg18180107 chr4:99064573 C4orf37 0.6 4.75 0.39 5.58e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.603 rs2223411 chr6:146028767 T/C cg13319975 chr6:146136371 FBXO30 0.68 6.18 0.49 8.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4253772 0.591 rs6007732 chr22:46652303 A/T cg09491104 chr22:46646882 C22orf40 -0.63 -6.48 -0.5 1.94e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs4820539 0.966 rs5751590 chr22:23486830 A/C cg14186256 chr22:23484241 RTDR1 1.03 13.59 0.77 2.61e-26 Bone mineral density; TGCT cis rs11874712 0.931 rs8095608 chr18:43678911 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.14 0.42 1.03e-6 Migraine - clinic-based; TGCT cis rs4699052 0.625 rs6828829 chr4:104335667 A/G cg16532752 chr4:104119610 CENPE -0.53 -5.22 -0.42 7.32e-7 Testicular germ cell tumor; TGCT cis rs7714584 1.000 rs1428552 chr5:150259831 T/C cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs8056742 0.730 rs34776453 chr16:85098298 T/C cg00229868 chr16:85520891 NA 0.38 4.77 0.39 5.03e-6 Amyotrophic lateral sclerosis; TGCT cis rs9915657 1.000 rs9915657 chr17:70127536 T/C cg06234051 chr17:70120541 SOX9 -0.29 -5.66 -0.45 9.85e-8 Thyroid hormone levels; TGCT cis rs1670533 1.000 rs10084849 chr4:1053586 T/C cg20887711 chr4:1340912 KIAA1530 0.69 5.54 0.45 1.69e-7 Recombination rate (females); TGCT cis rs6570726 0.791 rs4335004 chr6:145904764 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.58 -0.38 1.13e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs11623869 0.614 rs11627052 chr14:103863476 A/G cg26031613 chr14:104095156 KLC1 -0.67 -5.37 -0.43 3.79e-7 Bone mineral density; TGCT cis rs9399137 0.507 rs7745289 chr6:135380327 A/G cg24558204 chr6:135376177 HBS1L 0.47 4.73 0.39 5.98e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs13191362 1.000 rs34931503 chr6:163003876 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1903068 0.752 rs28517654 chr4:55993468 T/C cg01777861 chr4:56023843 NA 0.53 6.16 0.48 9.28e-9 Endometriosis; TGCT cis rs8044995 0.563 rs3785127 chr16:68399590 C/G cg05110241 chr16:68378359 PRMT7 -0.36 -4.46 -0.37 1.84e-5 Schizophrenia; TGCT cis rs9291683 0.588 rs17246745 chr4:9994583 T/C cg02734326 chr4:10020555 SLC2A9 0.38 4.52 0.38 1.42e-5 Bone mineral density; TGCT cis rs911555 0.755 rs1116095 chr14:103931879 A/G cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs2299587 0.623 rs7009476 chr8:17770376 T/C cg01800426 chr8:17659068 MTUS1 -0.67 -5.71 -0.46 8.04e-8 Economic and political preferences; TGCT cis rs12893668 0.603 rs12896171 chr14:104135966 A/G cg26031613 chr14:104095156 KLC1 -0.59 -5.08 -0.42 1.34e-6 Reticulocyte count; TGCT cis rs9611565 0.546 rs5758430 chr22:42109844 G/T cg06481639 chr22:41940642 POLR3H 0.71 6.48 0.5 1.95e-9 Vitiligo; TGCT cis rs7666738 0.830 rs7672127 chr4:98938477 A/G cg05340658 chr4:99064831 C4orf37 0.54 6.09 0.48 1.28e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6089829 0.962 rs6062777 chr20:61663748 G/A cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg22166914 chr1:53195759 ZYG11B 0.34 5.57 0.45 1.52e-7 Monocyte count; TGCT cis rs10791097 0.694 rs4937583 chr11:130741606 A/G cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9677476 0.516 rs10202806 chr2:232050852 A/G cg07929768 chr2:232055508 NA 0.33 5.26 0.43 6.24e-7 Food antigen IgG levels; TGCT cis rs6666258 1.000 rs6691463 chr1:154814538 C/G cg06418219 chr1:154948305 SHC1;CKS1B 0.65 5.26 0.43 6.14e-7 Atrial fibrillation; TGCT cis rs11673344 0.523 rs17206540 chr19:37559911 A/G cg08039142 chr19:36980659 ZNF566 0.49 4.5 0.37 1.57e-5 Obesity-related traits; TGCT cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg13342137 chr4:2252803 MXD4 0.17 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs61008539 0.821 rs10950789 chr7:897492 A/G cg15782153 chr7:917662 C7orf20 0.52 6.5 0.5 1.76e-9 Perceived unattractiveness to mosquitoes; TGCT cis rs28595532 0.920 rs115118317 chr4:119736613 C/T cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs9326248 1.000 rs7946257 chr11:117053165 A/G cg26566898 chr11:117069891 TAGLN 0.34 4.75 0.39 5.44e-6 Blood protein levels; TGCT cis rs7772486 0.727 rs6941429 chr6:145952283 G/A cg13319975 chr6:146136371 FBXO30 -0.56 -5.06 -0.41 1.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7829975 0.714 rs4841040 chr8:8654527 T/C cg15556689 chr8:8085844 FLJ10661 0.71 6.31 0.49 4.46e-9 Mood instability; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg02073558 chr3:44770973 ZNF501 0.69 6.85 0.52 3.06e-10 Depressive symptoms; TGCT cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.81 0.4 4.21e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1723838 0.510 rs80217992 chr11:73694260 C/G cg26954736 chr11:73693896 UCP2 -1.41 -6.38 -0.5 3.22e-9 Obesity-related traits; TGCT cis rs9926296 0.632 rs4785716 chr16:89801127 T/C cg08627397 chr16:89984028 MC1R -0.32 -5.18 -0.42 8.68e-7 Vitiligo; TGCT cis rs72945132 0.882 rs947812 chr11:70209169 C/T cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs9914544 0.545 rs8068683 chr17:18761827 T/G cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs3008870 1.000 rs3008853 chr1:67385488 C/T cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg18252515 chr7:66147081 NA -1.1 -7.18 -0.54 5.77e-11 Diabetic kidney disease; TGCT cis rs2204008 0.744 rs1115514 chr12:38280140 C/T cg13010199 chr12:38710504 ALG10B 0.59 4.61 0.38 9.88e-6 Bladder cancer; TGCT cis rs7923609 1.000 rs10822163 chr10:65124098 C/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.14e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs960450 0.826 rs9992841 chr4:98535757 T/C cg05340658 chr4:99064831 C4orf37 -0.4 -4.61 -0.38 9.89e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs7917772 0.503 rs7893155 chr10:104294228 C/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs950776 0.642 rs34694149 chr15:78965917 C/T cg03762349 chr15:79060523 ADAMTS7 0.28 5.42 0.44 2.98e-7 Sudden cardiac arrest; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg04234412 chr22:24373322 LOC391322 -0.72 -7.61 -0.56 6.11e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs597539 0.652 rs1249474 chr11:68654774 C/T cg21862992 chr11:68658383 NA 0.42 5.81 0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11098499 0.865 rs9994730 chr4:120381564 A/C cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7666738 0.830 rs4619898 chr4:98959646 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4509693 1.000 rs4277047 chr10:102499416 T/A cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs9972944 0.729 rs7209787 chr17:63769896 G/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs6964587 0.692 rs4729018 chr7:91644613 C/T cg17063962 chr7:91808500 NA 0.75 7.1 0.54 8.68e-11 Breast cancer; TGCT cis rs7267979 0.604 rs242130 chr20:25594020 C/A cg03522245 chr20:25566470 NINL -0.54 -5.46 -0.44 2.46e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12540874 0.759 rs12718572 chr7:50573325 C/T cg18232548 chr7:50535776 DDC -0.37 -6.38 -0.5 3.26e-9 Systemic sclerosis; TGCT cis rs2239547 0.522 rs9865094 chr3:52985319 G/C cg10802521 chr3:52805072 NEK4 0.64 6.1 0.48 1.26e-8 Schizophrenia; TGCT trans rs62103177 0.525 rs4799116 chr18:77736735 A/G cg05926928 chr17:57297772 GDPD1 -0.77 -6.89 -0.53 2.54e-10 Opioid sensitivity; TGCT cis rs734999 0.505 rs4073285 chr1:2539796 C/T cg18854424 chr1:2615690 NA 0.41 4.58 0.38 1.13e-5 Ulcerative colitis; TGCT cis rs9300255 0.539 rs1969355 chr12:123742061 G/A cg00376283 chr12:123451042 ABCB9 0.78 6.65 0.51 8.25e-10 Neutrophil percentage of white cells; TGCT cis rs1941023 0.584 rs2241920 chr11:60164204 A/G cg08716584 chr11:60157161 MS4A7 0.33 5.01 0.41 1.84e-6 Congenital heart disease (maternal effect); TGCT cis rs35306767 0.761 rs11253538 chr10:1011166 C/T cg26597838 chr10:835615 NA 0.57 6.42 0.5 2.6e-9 Eosinophil percentage of granulocytes; TGCT cis rs72615157 0.634 rs2272343 chr7:99778285 A/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.6 -5.05 -0.41 1.54e-6 Lung function (FEV1/FVC); TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg23131131 chr22:24373011 LOC391322 -0.8 -8.69 -0.62 1.78e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11190604 1.000 rs1080698 chr10:102295114 G/T cg23241863 chr10:102295624 HIF1AN 0.66 4.85 0.4 3.62e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2153535 0.601 rs6906170 chr6:8543128 T/A cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.56e-7 Motion sickness; TGCT cis rs9926296 0.572 rs2376878 chr16:89885161 G/A cg04287289 chr16:89883240 FANCA 0.69 7.08 0.54 9.59e-11 Vitiligo; TGCT cis rs950169 0.887 rs220333 chr15:85091133 C/T cg17173187 chr15:85201210 NMB 0.52 5.53 0.44 1.79e-7 Schizophrenia; TGCT cis rs1552244 0.935 rs6805869 chr3:10119917 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs6429082 0.689 rs4659923 chr1:235709519 C/T cg26050004 chr1:235667680 B3GALNT2 -0.51 -4.47 -0.37 1.77e-5 Adiposity; TGCT cis rs7666738 0.830 rs58696666 chr4:99006913 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2730260 0.537 rs73169234 chr7:158882366 C/T cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs1865760 0.929 rs12195653 chr6:25958621 A/G cg16482183 chr6:26056742 HIST1H1C 0.5 4.45 0.37 1.9e-5 Height; TGCT cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.59 5.87 0.47 3.75e-8 Bipolar disorder; TGCT cis rs2046867 0.862 rs62252362 chr3:72855218 A/G cg25664220 chr3:72788482 NA -0.56 -7.07 -0.54 1.02e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs17030434 0.906 rs11099901 chr4:154671468 T/A cg14289246 chr4:154710475 SFRP2 -0.88 -7.18 -0.54 5.68e-11 Electrocardiographic conduction measures; TGCT cis rs4074961 0.527 rs2294875 chr1:38052445 C/T cg17933807 chr1:38061675 GNL2 1.06 15.42 0.81 1.27e-30 Axial length; TGCT cis rs2692947 0.794 rs2140938 chr2:96751395 T/C cg23100626 chr2:96804247 ASTL 0.39 4.59 0.38 1.09e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9653442 0.545 rs4851257 chr2:100775297 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.26 -0.43 6.14e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6089829 0.926 rs73921625 chr20:61660891 C/T cg03213289 chr20:61660250 NA -0.51 -5.59 -0.45 1.38e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs709400 0.628 rs12879085 chr14:103874420 G/A cg12935359 chr14:103987150 CKB 0.34 5.19 0.42 8.36e-7 Body mass index; TGCT cis rs9534288 0.797 rs6561281 chr13:46596601 C/T cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs7918232 0.941 rs4749228 chr10:27433618 C/T cg14442939 chr10:27389572 ANKRD26 -0.72 -5.35 -0.43 4.16e-7 Breast cancer; TGCT cis rs7829975 0.559 rs4841025 chr8:8603160 A/G cg15556689 chr8:8085844 FLJ10661 -0.65 -5.67 -0.45 9.37e-8 Mood instability; TGCT cis rs7088591 0.614 rs16911518 chr10:59752987 C/T cg07264682 chr10:60082823 NA 0.35 4.72 0.39 6.2e-6 Blood pressure; TGCT cis rs9653442 0.932 rs893245 chr2:100814893 C/T cg07810366 chr2:100720526 AFF3 -0.4 -6.07 -0.48 1.46e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs644799 0.562 rs1254989 chr11:95508121 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.59 6.03 0.48 1.77e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6484504 0.532 rs11031342 chr11:31309818 G/A cg26647111 chr11:31128758 NA -0.32 -4.64 -0.38 8.82e-6 Red blood cell count; TGCT cis rs1949733 0.675 rs2688235 chr4:8450546 T/C cg11789530 chr4:8429930 ACOX3 0.55 5.22 0.42 7.42e-7 Response to antineoplastic agents; TGCT cis rs2677744 0.597 rs16945091 chr15:91499081 A/T cg01710897 chr15:91497902 RCCD1 0.33 4.67 0.39 7.75e-6 Attention deficit hyperactivity disorder; TGCT cis rs2115630 0.967 rs8027779 chr15:85255385 T/C cg12501888 chr15:85177176 SCAND2 -0.5 -4.83 -0.4 3.89e-6 P wave terminal force; TGCT cis rs769267 0.965 rs2017964 chr19:19387149 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs40363 0.645 rs250630 chr16:3524242 C/T cg05754148 chr16:3507555 NAT15 0.43 5.14 0.42 1.02e-6 Tuberculosis; TGCT cis rs9733 0.596 rs11204697 chr1:150658971 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg02503808 chr4:7069936 GRPEL1 1.01 9.63 0.65 9.78e-17 Monocyte percentage of white cells; TGCT cis rs1862618 0.671 rs2591965 chr5:56236176 T/C cg24531977 chr5:56204891 C5orf35 0.68 7.22 0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs116095464 0.558 rs10055405 chr5:265666 C/T cg22857025 chr5:266934 NA -0.34 -6.58 -0.51 1.19e-9 Breast cancer; TGCT cis rs2749592 0.513 rs1208708 chr10:38085576 A/G cg02002400 chr10:38691563 CDC10L -0.38 -4.81 -0.4 4.22e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs17221829 0.710 rs1844198 chr11:89388187 T/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs2046867 0.774 rs1393585 chr3:72886722 A/G cg25664220 chr3:72788482 NA -0.57 -6.33 -0.49 4.08e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs6089829 0.962 rs1060490 chr20:61665871 A/G cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7772486 0.875 rs2814872 chr6:146310234 T/C cg13319975 chr6:146136371 FBXO30 -0.53 -4.68 -0.39 7.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2242116 0.760 rs4682845 chr3:46955404 G/C cg27129171 chr3:47204927 SETD2 0.62 6.06 0.48 1.54e-8 Birth weight; TGCT cis rs7647973 1.000 rs6446262 chr3:49401153 T/C cg06212747 chr3:49208901 KLHDC8B 0.59 4.68 0.39 7.32e-6 Menarche (age at onset); TGCT cis rs3087591 0.960 rs2905880 chr17:29546175 A/G cg24425628 chr17:29625626 OMG;NF1 0.44 6.67 0.51 7.64e-10 Hip circumference; TGCT cis rs79149102 0.579 rs2304904 chr15:75315975 G/A cg09165964 chr15:75287851 SCAMP5 -1.04 -5.48 -0.44 2.28e-7 Lung cancer; TGCT cis rs7104764 0.719 rs3782116 chr11:223119 T/C cg18336825 chr11:236787 PSMD13;SIRT3 0.91 8.99 0.63 3.42e-15 Menarche (age at onset); TGCT cis rs79349575 0.783 rs9747646 chr17:47016882 C/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs2486012 0.737 rs37466 chr1:44283071 T/C cg12908607 chr1:44402522 ARTN -0.69 -5.19 -0.42 8.38e-7 Intelligence (multi-trait analysis); TGCT cis rs231513 0.593 rs76204283 chr17:42111092 A/G cg26893861 chr17:41843967 DUSP3 0.92 5.22 0.42 7.31e-7 Cognitive function; TGCT trans rs797680 0.856 rs797681 chr1:93717746 T/C cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs3820068 0.603 rs6668726 chr1:15962614 G/A cg05660106 chr1:15850417 CASP9 0.83 8.19 0.59 2.78e-13 Systolic blood pressure; TGCT cis rs858239 0.863 rs466225 chr7:23332403 G/T cg05602783 chr7:23145260 KLHL7 -0.58 -4.64 -0.38 8.55e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs11085466 1.000 rs75079001 chr19:21757375 A/G cg23026602 chr19:21646605 NA -0.57 -4.59 -0.38 1.07e-5 Colorectal or endometrial cancer; TGCT cis rs9926296 0.712 rs258330 chr16:89729574 T/G cg04287289 chr16:89883240 FANCA -0.54 -5.01 -0.41 1.86e-6 Vitiligo; TGCT cis rs7772486 0.875 rs2748498 chr6:146319166 C/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.54 -0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs8177253 0.965 rs4854761 chr3:133498789 A/G cg08048268 chr3:133502702 NA 0.65 9.75 0.66 5.07e-17 Iron status biomarkers; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg11905131 chr22:24372483 LOC391322 -0.85 -9.56 -0.65 1.43e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs3806843 0.551 rs246018 chr5:140335043 T/C cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg05025164 chr4:1340916 KIAA1530 0.78 6.86 0.52 2.86e-10 Longevity; TGCT cis rs11098499 0.954 rs12499324 chr4:120393786 C/T cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs514406 1.000 rs514406 chr1:53330458 A/G cg25767906 chr1:53392781 SCP2 -0.58 -5.2 -0.42 7.82e-7 Monocyte count; TGCT cis rs7267979 1.000 rs2482937 chr20:25340786 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4803468 0.967 rs13344547 chr19:41945848 G/T cg09537434 chr19:41945824 ATP5SL 0.92 10.36 0.68 1.69e-18 Height; TGCT cis rs7582180 0.701 rs11693044 chr2:100922313 T/C cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs9818758 0.556 rs9872660 chr3:49378832 G/T cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.59 0.38 1.08e-5 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9926296 0.744 rs154657 chr16:89708096 A/G cg26513180 chr16:89883248 FANCA 0.61 5.73 0.46 7.18e-8 Vitiligo; TGCT cis rs4450131 0.618 rs7075794 chr10:126338093 A/G cg20435097 chr10:126320824 FAM53B 0.18 4.44 0.37 1.95e-5 White blood cell count (basophil); TGCT cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs1525293 1.000 rs10950235 chr7:70480631 C/T cg21135135 chr7:70597687 WBSCR17 -0.44 -4.62 -0.38 9.46e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs6484504 0.532 rs1929019 chr11:31267030 C/T cg14844989 chr11:31128820 NA -0.25 -4.72 -0.39 6.21e-6 Red blood cell count; TGCT cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg16049864 chr8:95962084 TP53INP1 0.69 8.72 0.62 1.56e-14 Type 2 diabetes; TGCT cis rs7027203 0.828 rs7037960 chr9:96584028 G/A cg14598338 chr9:96623480 NA -0.61 -9.56 -0.65 1.43e-16 DNA methylation (variation); TGCT cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg22105103 chr4:187893119 NA 0.34 4.86 0.4 3.41e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2439831 0.681 rs2278859 chr15:43632960 A/C cg02155558 chr15:43621948 ADAL;LCMT2 1.05 9.14 0.63 1.54e-15 Lung cancer in ever smokers; TGCT cis rs62380364 0.602 rs640177 chr5:88002084 T/A cg24804195 chr5:87968844 LOC645323 -0.59 -5.71 -0.46 7.96e-8 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.875 rs9322043 chr6:146352690 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.65 -0.39 8.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9653442 0.564 rs10197987 chr2:100790783 A/T cg07810366 chr2:100720526 AFF3 -0.35 -5.23 -0.43 6.98e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs12530845 0.943 rs58577912 chr7:135329269 T/G cg23117316 chr7:135346802 PL-5283 -0.5 -4.74 -0.39 5.83e-6 Red blood cell traits; TGCT cis rs10464366 0.544 rs12701697 chr7:39182165 C/T cg18850127 chr7:39170497 POU6F2 0.33 7.18 0.54 5.5e-11 IgG glycosylation; TGCT cis rs5750830 0.594 rs6001568 chr22:39775786 G/A cg05872129 chr22:39784769 NA -0.85 -8.99 -0.63 3.42e-15 Intelligence (multi-trait analysis); TGCT trans rs561341 0.689 rs578635 chr17:30289897 A/C cg20587970 chr11:113659929 NA -0.63 -6.84 -0.52 3.25e-10 Hip circumference adjusted for BMI; TGCT cis rs9916302 0.904 rs585961 chr17:37444036 G/A cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT trans rs1814175 0.702 rs4881644 chr11:49786367 C/T cg03929089 chr4:120376271 NA -0.69 -8.17 -0.59 3.03e-13 Height; TGCT trans rs7864133 1.000 rs11139253 chr9:84063913 T/C cg23451063 chr7:1059876 C7orf50 0.55 6.93 0.53 2.02e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs3008870 0.628 rs2755257 chr1:67515309 C/T cg02640540 chr1:67518911 SLC35D1 0.63 5.95 0.47 2.55e-8 Lymphocyte percentage of white cells; TGCT cis rs2153535 0.580 rs2183112 chr6:8528212 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs10992471 0.756 rs7043152 chr9:95138499 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.31 -0.49 4.46e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs17030434 1.000 rs12645134 chr4:154713430 T/C cg14289246 chr4:154710475 SFRP2 -0.91 -7.28 -0.55 3.3e-11 Electrocardiographic conduction measures; TGCT cis rs10875746 0.669 rs1021313 chr12:48638041 T/A cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg00684032 chr4:1343700 KIAA1530 0.22 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs910316 0.737 rs175084 chr14:75519175 C/T cg11812906 chr14:75593930 NEK9 -0.63 -5.74 -0.46 6.72e-8 Height; TGCT cis rs1005277 0.522 rs289647 chr10:37968278 A/G cg25427524 chr10:38739819 LOC399744 -0.32 -6.35 -0.5 3.63e-9 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg21724239 chr8:58056113 NA 0.44 4.57 0.38 1.18e-5 Developmental language disorder (linguistic errors); TGCT cis rs12136530 0.577 rs12120180 chr1:19791441 C/T cg03884082 chr1:19971709 NBL1 0.43 4.51 0.38 1.5e-5 Lead levels in blood; TGCT cis rs7178424 0.875 rs2414753 chr15:62200974 T/C cg00456672 chr15:62358751 C2CD4A -0.31 -4.69 -0.39 7.14e-6 Height; TGCT cis rs73416724 0.544 rs111739263 chr6:43243151 G/T cg24109273 chr6:43484729 YIPF3;POLR1C 0.9 4.48 0.37 1.69e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs28551159 1 rs28551159 chr6:26376368 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Urinary tract infection frequency; TGCT cis rs9653442 0.564 rs13013594 chr2:100784190 A/G cg22139774 chr2:100720529 AFF3 -0.36 -5.69 -0.46 8.67e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9419702 0.538 rs9419628 chr10:133539299 A/C cg23460707 chr10:133558971 NA 0.44 4.83 0.4 4.01e-6 Survival in rectal cancer; TGCT cis rs950169 0.959 rs12902070 chr15:84793558 T/C cg12863693 chr15:85201151 NMB 0.38 4.45 0.37 1.9e-5 Schizophrenia; TGCT trans rs3780486 1.000 rs12342831 chr9:33124872 A/G cg20290983 chr6:43655470 MRPS18A 1.08 10.71 0.69 2.34e-19 IgG glycosylation; TGCT cis rs832540 0.556 rs4146565 chr5:56093825 T/C cg12311346 chr5:56204834 C5orf35 -0.49 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs3806843 0.547 rs246010 chr5:140336635 A/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs533581 0.844 rs564669 chr16:88968540 T/C cg16701003 chr16:89028210 CBFA2T3 0.33 4.79 0.39 4.77e-6 Social autistic-like traits; TGCT cis rs9790314 1.000 rs9872514 chr3:161042833 T/C cg03342759 chr3:160939853 NMD3 -0.42 -4.53 -0.38 1.38e-5 Morning vs. evening chronotype; TGCT trans rs2832077 0.527 rs2776210 chr21:30268558 A/G cg14791747 chr16:20752902 THUMPD1 -1.07 -12.65 -0.75 4.54e-24 Cognitive test performance; TGCT cis rs4689592 0.619 rs3796908 chr4:7061378 G/A cg02503808 chr4:7069936 GRPEL1 1.04 10.28 0.68 2.58e-18 Monocyte percentage of white cells; TGCT cis rs921968 0.541 rs488767 chr2:219466860 G/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6964587 0.934 rs73226382 chr7:91692760 T/C cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs72700829 0.531 rs955955 chr1:151011543 G/A cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Schizophrenia; TGCT cis rs10782582 0.609 rs72979226 chr1:76302222 C/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs2594989 0.616 rs6442254 chr3:11474491 T/C cg00170343 chr3:11313890 ATG7 0.74 5.52 0.44 1.9e-7 Circulating chemerin levels; TGCT trans rs6089829 0.926 rs1060489 chr20:61665921 C/T cg13615516 chr5:77269221 NA 0.69 8.57 0.61 3.51e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs11785400 1.000 rs4736365 chr8:143742197 A/G cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs6604026 0.630 rs56193705 chr1:93455887 C/G cg17283838 chr1:93427260 FAM69A 0.57 4.64 0.38 8.79e-6 Multiple sclerosis; TGCT cis rs7246657 1.000 rs1529957 chr19:37739801 A/G cg03233940 chr19:37894644 NA -0.37 -4.79 -0.39 4.73e-6 Coronary artery calcification; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg10150615 chr22:24372951 LOC391322 -0.86 -10.22 -0.68 3.68e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1218582 0.772 rs906593 chr1:154885255 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs9467711 1.000 rs1883215 chr6:26314233 G/C cg16898833 chr6:26189333 HIST1H4D 0.99 4.9 0.4 2.95e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg27535305 chr1:53392650 SCP2 -0.28 -5.93 -0.47 2.85e-8 Monocyte count; TGCT cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs2463822 0.669 rs72919493 chr11:62049651 C/A cg06239285 chr11:62104954 ASRGL1 -0.82 -4.63 -0.38 9.15e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs4233949 1.000 rs4233949 chr2:54659707 C/G cg14634210 chr2:54682758 SPTBN1 -0.54 -4.55 -0.38 1.26e-5 Bone mineral density; TGCT cis rs10779751 1.000 rs12120734 chr1:11262020 A/G cg08854313 chr1:11322531 MTOR 0.94 10.22 0.68 3.73e-18 Body mass index; TGCT cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.57e-7 Developmental language disorder (linguistic errors); TGCT cis rs7267979 1.000 rs6083856 chr20:25407585 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2594989 0.943 rs9836989 chr3:11463637 G/A cg00170343 chr3:11313890 ATG7 0.67 5.12 0.42 1.13e-6 Circulating chemerin levels; TGCT cis rs4242434 0.672 rs11785031 chr8:22486612 A/G cg03733263 chr8:22462867 KIAA1967 0.98 13.14 0.76 2.97e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2239547 0.603 rs17304995 chr3:53070755 A/G cg10802521 chr3:52805072 NEK4 -0.58 -5.26 -0.43 6.15e-7 Schizophrenia; TGCT cis rs10751667 0.666 rs4072741 chr11:976565 T/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs8141529 0.778 rs5762795 chr22:29182500 C/A cg02153584 chr22:29168773 CCDC117 0.75 6.44 0.5 2.33e-9 Lymphocyte counts; TGCT cis rs7226408 0.857 rs12185461 chr18:34492036 A/G cg06757138 chr18:34340585 FHOD3 -0.25 -4.88 -0.4 3.21e-6 Obesity-related traits; TGCT cis rs1005224 0.853 rs6574251 chr14:76136883 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.66 -5.92 -0.47 2.97e-8 Large artery stroke; TGCT cis rs782590 0.967 rs62165172 chr2:55736237 A/G cg18811423 chr2:55921094 PNPT1 0.67 7.22 0.54 4.57e-11 Metabolic syndrome; TGCT cis rs6903823 0.527 rs4713158 chr6:28277771 C/A cg18815343 chr6:28367644 ZSCAN12 -0.46 -4.8 -0.4 4.46e-6 Pulmonary function; TGCT cis rs7615952 0.932 rs7629977 chr3:125649573 T/G cg05084668 chr3:125655381 ALG1L -0.76 -6.21 -0.49 7.43e-9 Blood pressure (smoking interaction); TGCT cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg08645402 chr16:4508243 NA 0.21 5.18 0.42 8.63e-7 Schizophrenia; TGCT cis rs10782582 0.593 rs6664254 chr1:76235084 G/T cg10523679 chr1:76189770 ACADM -0.61 -6.13 -0.48 1.09e-8 Daytime sleep phenotypes; TGCT cis rs12950390 0.893 rs72831644 chr17:45824391 T/C cg24803719 chr17:45855879 NA -0.48 -4.81 -0.4 4.3e-6 IgG glycosylation; TGCT cis rs11190604 1.000 rs6584379 chr10:102224490 G/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs7552404 0.727 rs6683437 chr1:76316619 G/A cg10523679 chr1:76189770 ACADM 0.68 6.36 0.5 3.5e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.13 0.82 3.12e-32 Prudent dietary pattern; TGCT cis rs4499344 0.623 rs259278 chr19:33161126 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.91 10.19 0.68 4.27e-18 Mean platelet volume; TGCT cis rs10744422 0.858 rs12426809 chr12:123327143 C/T cg25930673 chr12:123319894 HIP1R -0.85 -5.01 -0.41 1.86e-6 Schizophrenia; TGCT cis rs6977660 0.714 rs4721824 chr7:19785898 A/G cg05791153 chr7:19748676 TWISTNB 0.84 4.71 0.39 6.52e-6 Thyroid stimulating hormone; TGCT cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs600231 0.706 rs10896016 chr11:65335705 C/T cg17120908 chr11:65337727 SSSCA1 0.57 5.78 0.46 5.72e-8 Bone mineral density; TGCT cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2228479 0.867 rs11646448 chr16:89966357 A/T cg19635926 chr16:89946313 TCF25 0.26 4.56 0.38 1.2e-5 Skin colour saturation; TGCT cis rs992157 0.730 rs2891078 chr2:219184432 C/T cg00012203 chr2:219082015 ARPC2 0.7 6.59 0.51 1.11e-9 Colorectal cancer; TGCT cis rs9473924 0.542 rs9473928 chr6:50842003 G/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs9913156 0.553 rs1045280 chr17:4622638 C/T cg19197139 chr17:4613644 ARRB2 -0.59 -5.36 -0.43 3.96e-7 Lymphocyte counts; TGCT cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7119 0.745 rs11632602 chr15:77809764 C/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs2710642 0.888 rs28447553 chr2:63224563 A/G cg17519650 chr2:63277830 OTX1 0.58 5.05 0.41 1.53e-6 LDL cholesterol levels;LDL cholesterol; TGCT cis rs2637266 0.935 rs1907300 chr10:78325091 A/G cg18941641 chr10:78392320 NA 0.42 5.38 0.43 3.6e-7 Pulmonary function; TGCT cis rs7772486 0.790 rs4075694 chr6:146251108 G/C cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9650657 0.585 rs7830317 chr8:10700254 A/C cg27411982 chr8:10470053 RP1L1 -0.23 -4.65 -0.39 8.22e-6 Neuroticism; TGCT cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.53 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs1075232 1.000 rs16956707 chr15:31641633 G/A cg01030201 chr15:31746330 NA -1.01 -5.25 -0.43 6.38e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs1461503 0.966 rs1461501 chr11:122844416 A/G cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT trans rs210152 0.588 rs210131 chr6:33535466 T/C cg00293626 chr8:143463227 TSNARE1 -0.44 -6.78 -0.52 4.27e-10 Schizophrenia; TGCT cis rs904251 0.828 rs1757174 chr6:37486695 G/A cg25019722 chr6:37503610 NA -0.51 -7.0 -0.53 1.43e-10 Cognitive performance; TGCT cis rs1949733 1.000 rs2631740 chr4:8484106 C/A cg11789530 chr4:8429930 ACOX3 -0.65 -6.0 -0.47 1.99e-8 Response to antineoplastic agents; TGCT cis rs1042058 0.565 rs650110 chr10:30753132 A/G cg18806716 chr10:30721971 MAP3K8 -0.57 -6.89 -0.53 2.46e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg21951975 chr1:209979733 IRF6 0.73 5.94 0.47 2.72e-8 Cleft lip with or without cleft palate; TGCT cis rs8017423 0.967 rs4904656 chr14:90721442 G/T cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.49e-12 Mortality in heart failure; TGCT cis rs3733585 0.699 rs4473653 chr4:9971058 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.72 -0.52 5.74e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4478037 1.000 rs56733391 chr3:33161434 G/A cg19404215 chr3:33155277 CRTAP 1.39 9.26 0.64 7.94e-16 Major depressive disorder; TGCT cis rs72843506 0.591 rs75334890 chr17:20221400 A/G cg18979559 chr17:20280153 CCDC144C -0.67 -4.89 -0.4 3.04e-6 Schizophrenia; TGCT cis rs3540 0.513 rs2601182 chr15:90925430 A/T cg22089800 chr15:90895588 ZNF774 0.82 9.2 0.64 1.09e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9389248 0.690 rs2064101 chr6:135250530 G/A cg24558204 chr6:135376177 HBS1L -0.47 -4.81 -0.4 4.35e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs2288884 0.779 rs10411428 chr19:52607765 C/T cg13540795 chr19:52551618 ZNF432 -0.6 -5.81 -0.46 5.06e-8 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs1372520 0.684 rs2572318 chr4:90718719 C/T cg14346243 chr4:90757452 SNCA -0.66 -4.74 -0.39 5.7e-6 Neuroticism; TGCT cis rs4718428 0.705 rs4717331 chr7:66378886 C/T cg18252515 chr7:66147081 NA -0.59 -4.49 -0.37 1.6e-5 Corneal structure; TGCT cis rs611744 0.816 rs626211 chr8:109189448 A/C cg21045802 chr8:109455806 TTC35 0.68 6.03 0.48 1.72e-8 Dupuytren's disease; TGCT cis rs941873 0.838 rs2233713 chr10:81107135 A/C cg09469691 chr10:81107165 PPIF 0.65 6.69 0.51 6.97e-10 Height; TGCT cis rs11514810 1.000 rs7812242 chr7:1431747 C/T cg24899294 chr7:1481343 MICALL2 -0.45 -5.73 -0.46 7.11e-8 Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder; TGCT cis rs3905510 0.903 rs10085115 chr5:123001137 C/T cg15125798 chr5:122621645 NA -0.59 -4.69 -0.39 7.12e-6 Total body bone mineral density; TGCT cis rs12134133 0.752 rs61821050 chr1:207408598 C/A cg02152968 chr1:207494213 CD55 0.69 4.75 0.39 5.46e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7909074 0.966 rs4245614 chr10:45397007 C/T cg04218760 chr10:45406644 TMEM72 -0.27 -5.36 -0.43 3.95e-7 Mean corpuscular volume; TGCT cis rs6500602 0.727 rs4786509 chr16:4568769 C/G cg09549813 chr16:4587862 C16orf5 0.28 4.51 0.38 1.5e-5 Schizophrenia; TGCT cis rs8017423 0.615 rs12586761 chr14:90820897 A/G cg04374321 chr14:90722782 PSMC1 -0.56 -5.62 -0.45 1.19e-7 Mortality in heart failure; TGCT cis rs11792861 0.851 rs17552292 chr9:111891954 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.47 0.37 1.73e-5 Menarche (age at onset); TGCT cis rs2075371 0.611 rs12531769 chr7:134016899 C/G cg11752832 chr7:134001865 SLC35B4 0.63 5.1 0.42 1.23e-6 Mean platelet volume; TGCT cis rs2228479 0.850 rs17226966 chr16:89825338 A/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7246657 0.722 rs10417576 chr19:38119212 A/C cg03611452 chr19:38183253 ZNF781 0.59 4.76 0.39 5.34e-6 Coronary artery calcification; TGCT trans rs1496653 0.544 rs35497505 chr3:23425798 G/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs858239 0.730 rs858289 chr7:23248158 C/T cg05407003 chr7:23246146 NA -0.28 -4.54 -0.38 1.29e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs2227564 0.620 rs10740418 chr10:75519322 T/C cg19442545 chr10:75533431 FUT11 -0.31 -4.55 -0.38 1.26e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1153858 1.000 rs3809472 chr15:45694318 G/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs909002 0.800 rs1061770 chr1:32096265 A/G cg11573219 chr1:32083031 HCRTR1 -0.43 -5.6 -0.45 1.33e-7 Intelligence (multi-trait analysis); TGCT cis rs11935103 0.673 rs1470753 chr4:187296119 A/G cg16785698 chr4:186456103 PDLIM3 0.44 4.47 0.37 1.74e-5 Response to citalopram treatment; TGCT cis rs9611565 0.729 rs202654 chr22:41841034 G/A cg13695892 chr22:41940480 POLR3H 0.86 8.55 0.61 3.95e-14 Vitiligo; TGCT cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11098499 0.954 rs6846442 chr4:120326323 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs11264213 0.591 rs4653158 chr1:36556187 G/A cg27506609 chr1:36549197 TEKT2 -0.37 -6.07 -0.48 1.45e-8 Schizophrenia; TGCT cis rs288326 0.561 rs74953433 chr2:183872665 T/C cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs950169 1.000 rs1848093 chr15:84755527 G/C cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.14e-8 Schizophrenia; TGCT cis rs9527 0.662 rs10883783 chr10:104591152 T/A cg04362960 chr10:104952993 NT5C2 0.63 5.37 0.43 3.77e-7 Arsenic metabolism; TGCT cis rs526231 0.819 rs2569016 chr5:102603132 A/G cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs319204 1.000 rs319239 chr5:146238637 A/G cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs67073037 0.955 rs4666131 chr2:29136272 T/C cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs2673604 0.600 rs2673600 chr8:133414416 C/G cg05740582 chr8:133573933 HPYR1 -0.31 -4.48 -0.37 1.65e-5 Interleukin-8 levels; TGCT cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs3784262 0.565 rs9635346 chr15:58298118 C/G cg12031962 chr15:58353849 ALDH1A2 0.38 5.53 0.44 1.82e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6684514 1.000 rs12038203 chr1:156248265 C/T cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs11098499 0.863 rs13136462 chr4:120543173 C/T cg09307838 chr4:120376055 NA 0.67 6.29 0.49 5.06e-9 Corneal astigmatism; TGCT cis rs2153535 0.580 rs7775909 chr6:8477778 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7213347 0.611 rs1231207 chr17:2125450 A/C cg20777128 chr17:1945076 DPH1;OVCA2 -0.51 -4.6 -0.38 1.01e-5 Total body bone mineral density; TGCT cis rs9733 0.818 rs10888388 chr1:150687296 C/T cg13175981 chr1:150552382 MCL1 0.43 4.78 0.39 4.88e-6 Tonsillectomy; TGCT cis rs4986172 0.726 rs12946454 chr17:43208121 A/T cg10701640 chr17:43249399 NA 0.52 6.28 0.49 5.25e-9 Height; TGCT cis rs7267979 0.966 rs4815414 chr20:25361701 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9399135 0.967 rs11755229 chr6:135369913 A/G cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs68170813 0.562 rs7810216 chr7:107000353 G/A cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg21724239 chr8:58056113 NA 0.38 5.17 0.42 9.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6088580 0.608 rs8114616 chr20:32969092 G/T cg08999081 chr20:33150536 PIGU -0.26 -5.13 -0.42 1.09e-6 Glomerular filtration rate (creatinine); TGCT cis rs763014 1.000 rs8054842 chr16:672799 T/C cg09263875 chr16:632152 PIGQ 0.3 6.44 0.5 2.41e-9 Height; TGCT cis rs9372253 0.678 rs9487392 chr6:110708626 C/T cg01119278 chr6:110721349 DDO 0.31 4.73 0.39 6.05e-6 Platelet distribution width; TGCT cis rs1420338 0.933 rs62451689 chr7:34178719 C/T cg01275685 chr7:34179230 BMPER -0.28 -5.0 -0.41 1.88e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs7666738 0.830 rs1426667 chr4:98949772 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs9640161 0.711 rs55881542 chr7:150025734 G/A cg10018233 chr7:150070692 REPIN1 0.32 4.58 0.38 1.1e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs198426 0.506 rs11230766 chr11:61426582 A/T cg19838087 chr11:61442541 NA -0.2 -4.62 -0.38 9.43e-6 Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid); TGCT cis rs2243480 0.901 rs73142137 chr7:65343442 A/T cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg05985448 chr10:134359359 INPP5A 0.23 4.99 0.41 2.01e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs12220238 1.000 rs3812638 chr10:75896072 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.85 5.91 0.47 3.14e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7666738 0.830 rs13148363 chr4:98847498 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.1 0.42 1.22e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs751728 0.571 rs4713691 chr6:33790415 A/G cg13859433 chr6:33739653 LEMD2 0.34 5.66 0.45 1.01e-7 Crohn's disease; TGCT cis rs4689388 0.853 rs1079214 chr4:6282157 T/C cg00701064 chr4:6280414 WFS1 0.39 4.79 0.4 4.7e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs826838 1.000 rs11183160 chr12:38676702 T/C cg26384229 chr12:38710491 ALG10B 1.11 10.88 0.7 9.29e-20 Heart rate; TGCT cis rs4786125 0.665 rs1565634 chr16:6919370 T/C cg03623568 chr16:6915990 A2BP1 -0.45 -6.77 -0.52 4.65e-10 Heart rate variability traits (SDNN); TGCT cis rs57590327 0.679 rs13082940 chr3:81547264 C/T cg07356753 chr3:81810745 GBE1 0.55 4.54 0.38 1.3e-5 Extraversion; TGCT cis rs1372520 0.684 rs1811442 chr4:90747751 C/T cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs950776 0.518 rs12900783 chr15:78815523 G/A cg06917634 chr15:78832804 PSMA4 0.96 9.71 0.66 6.43e-17 Sudden cardiac arrest; TGCT trans rs3780486 0.757 rs10121987 chr9:33119818 A/G cg20290983 chr6:43655470 MRPS18A 1.2 14.8 0.8 3.47e-29 IgG glycosylation; TGCT cis rs7635838 0.565 rs346067 chr3:11252095 T/C cg00170343 chr3:11313890 ATG7 0.54 4.96 0.41 2.25e-6 HDL cholesterol; TGCT cis rs9291683 0.588 rs2240721 chr4:10020564 G/A cg00071950 chr4:10020882 SLC2A9 0.72 9.86 0.66 2.78e-17 Bone mineral density; TGCT cis rs3796352 0.892 rs2581807 chr3:53088844 G/A cg27565382 chr3:53032988 SFMBT1 -0.42 -4.79 -0.4 4.61e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3772130 0.962 rs9826473 chr3:121556219 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.51 4.7 0.39 6.82e-6 Cognitive performance; TGCT cis rs13188771 0.578 rs17137390 chr5:100918526 C/T cg18665594 chr5:101119420 NA 0.48 4.78 0.39 4.83e-6 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs9911578 0.704 rs72628393 chr17:56585314 A/T cg05425664 chr17:57184151 TRIM37 0.59 5.69 0.46 8.67e-8 Intelligence (multi-trait analysis); TGCT cis rs2282802 0.685 rs11745502 chr5:139558808 G/A cg01081189 chr5:139537190 NA -0.3 -5.37 -0.43 3.82e-7 Intelligence (multi-trait analysis); TGCT cis rs826838 0.935 rs7301104 chr12:39182821 C/T cg26384229 chr12:38710491 ALG10B 0.98 8.78 0.62 1.07e-14 Heart rate; TGCT cis rs7666738 0.830 rs11941961 chr4:99065654 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.92 0.47 2.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9388451 0.626 rs1343116 chr6:126069702 C/A cg10911889 chr6:126070802 HEY2 0.5 4.69 0.39 7.17e-6 Brugada syndrome; TGCT cis rs2326825 0.585 rs1317391 chr6:6803971 C/T cg06501113 chr6:6534839 LOC285780 -0.39 -5.1 -0.42 1.21e-6 Gastroesophageal reflux disease; TGCT cis rs875971 1.000 rs10244498 chr7:66116056 A/G cg11764359 chr7:65958608 NA 0.56 4.79 0.4 4.68e-6 Aortic root size; TGCT cis rs7824557 0.767 rs7837036 chr8:11175489 A/G cg21775007 chr8:11205619 TDH 0.54 5.18 0.42 8.68e-7 Retinal vascular caliber; TGCT cis rs2338224 1.000 rs9293309 chr5:71746822 A/G cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs7091068 0.566 rs7082701 chr10:95501042 G/T cg20715218 chr10:95462985 C10orf4 0.52 4.62 0.38 9.33e-6 Urinary tract infection frequency; TGCT cis rs2180341 0.960 rs3756996 chr6:127664258 G/C cg24812749 chr6:127587940 RNF146 1.01 7.58 0.56 7.11e-12 Breast cancer; TGCT cis rs7954584 0.616 rs10743185 chr12:122356435 G/A cg21016266 chr12:122356598 WDR66 0.43 5.65 0.45 1.03e-7 Mean corpuscular volume; TGCT cis rs250677 0.687 rs41181 chr5:148444257 C/G cg23229984 chr5:148520753 ABLIM3 -0.2 -4.7 -0.39 6.82e-6 Breast cancer; TGCT cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg12042659 chr19:58951599 ZNF132 0.57 5.08 0.42 1.35e-6 Uric acid clearance; TGCT cis rs887829 0.569 rs4663965 chr2:234650604 A/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.76 -0.39 5.4e-6 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs9985766 1.000 rs28392881 chr4:151007145 G/A cg05926478 chr4:151174724 DCLK2 -0.26 -5.19 -0.42 8.26e-7 Coronary artery disease;Myocardial infarction; TGCT cis rs9457247 0.508 rs2285147 chr6:167505548 G/A cg07741184 chr6:167504864 NA 0.26 4.88 0.4 3.21e-6 Crohn's disease; TGCT cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs2239547 0.522 rs4519686 chr3:52997871 C/T cg11645453 chr3:52864694 ITIH4 0.37 6.26 0.49 5.89e-9 Schizophrenia; TGCT cis rs6089829 0.962 rs4809455 chr20:61660781 G/C cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs7027203 1.000 rs7854820 chr9:96526027 A/G cg14598338 chr9:96623480 NA 0.58 8.58 0.61 3.19e-14 DNA methylation (variation); TGCT cis rs9902453 0.765 rs2127001 chr17:28098219 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.18 -0.59 2.89e-13 Coffee consumption (cups per day); TGCT cis rs60871478 0.636 rs55663559 chr7:884057 G/A cg15782153 chr7:917662 C7orf20 0.52 4.78 0.39 4.84e-6 Cerebrospinal P-tau181p levels; TGCT cis rs7668190 0.924 rs6554162 chr4:55093955 G/A cg17187183 chr4:55093834 PDGFRA 0.43 5.99 0.47 2.12e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg00080972 chr5:178986291 RUFY1 0.51 6.01 0.47 1.95e-8 Lung cancer; TGCT cis rs295140 0.526 rs295113 chr2:201197816 C/G cg04283868 chr2:201171347 SPATS2L -0.47 -4.45 -0.37 1.87e-5 QT interval; TGCT cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg12310025 chr6:25882481 NA -0.63 -5.71 -0.46 7.79e-8 Intelligence (multi-trait analysis); TGCT cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg04352962 chr1:209979756 IRF6 0.64 4.89 0.4 3.12e-6 Cleft lip with or without cleft palate; TGCT cis rs7769051 0.808 rs1467404 chr6:133090141 A/G cg22852734 chr6:133119734 C6orf192 -1.22 -6.88 -0.53 2.57e-10 Type 2 diabetes nephropathy; TGCT cis rs7267979 1.000 rs2474777 chr20:25272633 A/G cg14121845 chr20:25566513 NINL 0.5 5.39 0.44 3.37e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 1.000 rs6050617 chr20:25421648 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12210905 0.688 rs12212632 chr6:27472416 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs3087591 0.960 rs9807077 chr17:29634457 A/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.57 -0.56 7.2e-12 Hip circumference; TGCT trans rs2970818 0.831 rs7304949 chr12:4609625 A/G cg23020582 chr12:54734966 COPZ1 0.45 7.02 0.53 1.27e-10 Phosphorus levels; TGCT cis rs2797160 0.967 rs1343120 chr6:125992810 A/G cg05901451 chr6:126070800 HEY2 -0.74 -6.49 -0.5 1.84e-9 Endometrial cancer; TGCT cis rs13256369 0.851 rs13256611 chr8:8564341 G/A cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs514406 0.644 rs4926928 chr1:53210163 G/T cg25767906 chr1:53392781 SCP2 -0.44 -4.86 -0.4 3.44e-6 Monocyte count; TGCT cis rs769267 0.965 rs2017964 chr19:19387149 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs1552244 0.882 rs2130813 chr3:10038706 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.43 -0.5 2.53e-9 Alzheimer's disease; TGCT cis rs11190604 1.000 rs2495758 chr10:102321900 C/G cg16342193 chr10:102329863 NA -0.42 -5.26 -0.43 5.99e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg00786635 chr1:25594202 NA 0.52 5.56 0.45 1.59e-7 Erythrocyte sedimentation rate; TGCT cis rs4689388 0.853 rs1079214 chr4:6282157 T/C cg14416269 chr4:6271139 WFS1 0.4 5.13 0.42 1.07e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs68170813 0.559 rs78404515 chr7:106909126 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs34421088 0.506 rs2117616 chr8:11145911 A/G cg03192020 chr8:11204681 TDH -0.52 -4.58 -0.38 1.12e-5 Neuroticism; TGCT cis rs9527 0.590 rs1541213 chr10:104885330 A/G cg15744005 chr10:104629667 AS3MT -0.43 -4.94 -0.41 2.45e-6 Arsenic metabolism; TGCT cis rs67072384 1.000 rs67809272 chr11:72450941 T/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs597539 0.652 rs660614 chr11:68659488 G/A cg21862992 chr11:68658383 NA 0.47 6.67 0.51 7.49e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs2865979 chr4:99027137 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.43 0.5 2.55e-9 Cognitive function; TGCT cis rs7703051 0.520 rs13354746 chr5:74619132 C/T cg00601450 chr5:74908170 NA 0.45 5.02 0.41 1.73e-6 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs1903068 0.853 rs10012589 chr4:56002689 A/T cg09978860 chr4:56023921 NA 0.56 6.34 0.49 3.88e-9 Endometriosis; TGCT cis rs6912958 0.781 rs7750207 chr6:88303967 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.57 -0.38 1.14e-5 Monocyte percentage of white cells; TGCT cis rs3806843 0.576 rs251373 chr5:140252615 C/T cg09824255 chr5:140014002 CD14 -0.26 -4.54 -0.38 1.3e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs8017423 0.935 rs12884698 chr14:90750566 G/A cg04374321 chr14:90722782 PSMC1 -0.74 -6.98 -0.53 1.6e-10 Mortality in heart failure; TGCT cis rs9467773 0.566 rs66972160 chr6:26359306 T/C cg15659132 chr6:26577336 NA -0.53 -5.47 -0.44 2.37e-7 Intelligence (multi-trait analysis); TGCT cis rs7107174 0.688 rs869202 chr11:78127914 A/G cg12700464 chr11:78128424 GAB2 -0.67 -4.46 -0.37 1.83e-5 Testicular germ cell tumor; TGCT cis rs597539 0.652 rs1249474 chr11:68654774 C/T cg06028808 chr11:68637592 NA 0.49 6.3 0.49 4.76e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 7.0 0.53 1.44e-10 Platelet count; TGCT cis rs9381040 0.610 rs4140579 chr6:41041752 G/A cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs6674176 0.542 rs803675 chr1:44353237 G/A cg12908607 chr1:44402522 ARTN -0.7 -7.96 -0.58 9.2e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs72634258 0.554 rs68024107 chr1:7914066 G/C cg26816564 chr1:7831052 VAMP3 0.57 4.69 0.39 7.01e-6 Inflammatory bowel disease; TGCT cis rs4372836 0.504 rs62131973 chr2:29044437 T/G cg09522027 chr2:28974177 PPP1CB -0.56 -5.68 -0.45 9.2e-8 Body mass index; TGCT cis rs1218582 0.741 rs11264283 chr1:154869552 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.68 -6.83 -0.52 3.38e-10 Prostate cancer; TGCT cis rs797680 0.786 rs1559828 chr1:93825638 A/T cg17826107 chr1:92977322 EVI5 -0.24 -5.65 -0.45 1.05e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1865760 0.566 rs2032449 chr6:26026599 G/C cg17042849 chr6:26104293 HIST1H4C -0.61 -5.3 -0.43 5.08e-7 Height; TGCT cis rs6450176 0.909 rs6898870 chr5:53293107 G/A ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs8013055 0.796 rs4074453 chr14:105998544 T/C cg23356831 chr14:105996513 TMEM121 0.38 5.69 0.46 8.5e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs11190604 0.767 rs10883479 chr10:102162860 A/G cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2237234 0.580 rs7763910 chr6:26472655 C/T cg26531700 chr6:26746687 NA -0.5 -4.53 -0.38 1.37e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7659604 0.540 rs11734075 chr4:122695685 C/T cg19748678 chr4:122722346 EXOSC9 -0.57 -5.69 -0.45 8.7e-8 Type 2 diabetes; TGCT cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.75 -0.39 5.64e-6 Obesity-related traits; TGCT cis rs11190604 0.943 rs7085261 chr10:102209811 G/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs73198271 0.694 rs115037021 chr8:8647080 A/C cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9910055 0.530 rs7222349 chr17:42304644 C/T cg13607699 chr17:42295918 UBTF 0.96 11.06 0.7 3.33e-20 Total body bone mineral density; TGCT cis rs11748023 0.605 rs155943 chr5:139529987 A/T cg01081189 chr5:139537190 NA 0.27 4.75 0.39 5.62e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.789 rs2260197 chr20:25284343 T/C cg21995068 chr20:25989032 LOC100134868 -0.43 -5.19 -0.42 8.41e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3540 0.960 rs4031435 chr15:91015566 G/C cg22089800 chr15:90895588 ZNF774 0.74 6.9 0.53 2.33e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg09177884 chr7:1199841 ZFAND2A -0.52 -4.98 -0.41 2.04e-6 Longevity;Endometriosis; TGCT cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs916888 0.647 rs199524 chr17:44848438 G/T cg17911788 chr17:44343683 NA 0.51 5.9 0.47 3.3e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs35160687 0.901 rs13020869 chr2:86523360 C/T cg03171300 chr2:86307199 POLR1A 0.32 5.56 0.45 1.61e-7 Night sleep phenotypes; TGCT cis rs7772486 0.754 rs702306 chr6:145991029 T/C cg23711669 chr6:146136114 FBXO30 -0.93 -10.61 -0.69 4.16e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs8062405 0.573 rs7140 chr16:28995757 C/A cg01117621 chr16:28073818 GSG1L -0.37 -4.73 -0.39 6.13e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs208520 0.690 rs1233103 chr6:66855943 T/G cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs6460942 1.000 rs17191008 chr7:12417690 T/G cg06484146 chr7:12443880 VWDE -0.59 -5.6 -0.45 1.28e-7 Coronary artery disease; TGCT cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg17328964 chr8:145687451 CYHR1 -0.53 -8.54 -0.61 4.17e-14 Age at first birth; TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg05215272 chr17:6899095 ALOX12 -0.54 -6.45 -0.5 2.29e-9 Tonsillectomy; TGCT cis rs6671200 1.000 rs35143903 chr1:95622527 C/T cg20701556 chr1:95698924 RWDD3 0.63 5.22 0.42 7.28e-7 Stearic acid (18:0) levels; TGCT cis rs57994353 0.568 rs10870171 chr9:139318530 C/T cg13741927 chr9:139327495 INPP5E -0.24 -5.36 -0.43 3.96e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs7539409 0.651 rs970457 chr1:84296540 C/T cg10977910 chr1:84465055 TTLL7 0.9 5.47 0.44 2.39e-7 Alzheimer's disease; TGCT cis rs6061231 0.518 rs639836 chr20:60926223 G/A cg06026331 chr20:60912101 LAMA5 -0.26 -4.69 -0.39 7.23e-6 Colorectal cancer; TGCT cis rs4253772 0.637 rs8135997 chr22:46651366 G/A cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs3733346 0.553 rs6813110 chr4:942660 C/T cg22718636 chr4:961658 DGKQ 0.45 4.45 0.37 1.86e-5 Sjögren's syndrome; TGCT cis rs9926296 0.744 rs164748 chr16:89708292 C/G cg27121462 chr16:89883253 FANCA -0.49 -4.58 -0.38 1.11e-5 Vitiligo; TGCT cis rs12681287 0.547 rs9297922 chr8:87542317 A/G cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT cis rs7213347 0.707 rs216182 chr17:2173063 A/G cg13315690 chr17:1944831 OVCA2;DPH1 0.35 4.44 0.37 1.99e-5 Total body bone mineral density; TGCT cis rs35160687 0.901 rs11127026 chr2:86531748 C/T cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.48e-7 Night sleep phenotypes; TGCT cis rs7255374 0.566 rs11666982 chr19:41531368 T/G cg27089200 chr19:41531976 NA 0.5 6.92 0.53 2.19e-10 DDT metabolite (p,p'-DDE levels); TGCT trans rs1974653 0.711 rs9605066 chr22:20099654 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.65 -0.57 4.76e-12 Schizophrenia; TGCT cis rs2404602 0.618 rs12442266 chr15:76567142 T/C cg22467129 chr15:76604101 ETFA -0.62 -8.01 -0.58 7.08e-13 Blood metabolite levels; TGCT cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg19635926 chr16:89946313 TCF25 0.28 4.82 0.4 4.06e-6 Skin colour saturation; TGCT cis rs797680 0.897 rs12752223 chr1:93837133 T/C cg17826107 chr1:92977322 EVI5 -0.24 -5.72 -0.46 7.46e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.51 4.48 0.37 1.68e-5 Prudent dietary pattern; TGCT cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs60871478 1.000 rs4374882 chr7:821798 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.47 4.71 0.39 6.58e-6 Cerebrospinal P-tau181p levels; TGCT cis rs9811920 0.638 rs793461 chr3:99615758 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.82 -0.52 3.63e-10 Axial length; TGCT cis rs35934224 0.740 rs35142928 chr22:19847751 T/C cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.5 6.94 0.53 1.89e-10 Alzheimer's disease; TGCT cis rs9814567 1.000 rs6804770 chr3:134230234 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4972806 0.849 rs2071581 chr2:177026148 G/T cg14324370 chr2:177042789 NA 0.73 6.61 0.51 1.04e-9 IgG glycosylation; TGCT cis rs9303401 0.614 rs7215900 chr17:56654850 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.69 6.1 0.48 1.23e-8 Cognitive test performance; TGCT cis rs131777 0.508 rs140518 chr22:50999182 C/T cg25309564 chr22:51001381 C22orf41 0.77 6.97 0.53 1.68e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7666738 0.830 rs4699574 chr4:98725544 C/T cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs185694 1.000 rs613291 chr13:30894404 T/C cg07600127 chr13:30881527 KATNAL1 -0.82 -6.64 -0.51 8.92e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs9929218 1.000 rs12446575 chr16:68791644 C/G cg01251360 chr16:68772225 CDH1 0.29 4.89 0.4 3.01e-6 Colorectal cancer; TGCT cis rs2692947 0.770 rs12471925 chr2:96555522 C/A cg13655245 chr2:97463316 CNNM4 0.15 4.46 0.37 1.84e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs80033912 0.640 rs6785832 chr3:49224316 C/T cg02487422 chr3:49467188 NICN1 0.48 4.84 0.4 3.86e-6 Intelligence (multi-trait analysis); TGCT cis rs853679 0.567 rs13209596 chr6:28396190 C/A cg18815343 chr6:28367644 ZSCAN12 -0.5 -4.61 -0.38 9.72e-6 Depression; TGCT cis rs57590327 0.679 rs35395999 chr3:81613013 T/C cg07356753 chr3:81810745 GBE1 -0.57 -4.72 -0.39 6.37e-6 Extraversion; TGCT cis rs739496 0.501 rs441 chr12:112228849 T/C cg10833066 chr12:111807467 FAM109A 0.37 4.72 0.39 6.22e-6 Platelet count; TGCT cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg13683864 chr3:40499215 RPL14 -1.03 -10.36 -0.68 1.68e-18 Renal cell carcinoma; TGCT cis rs11621121 0.637 rs4902389 chr14:65793224 A/G cg04536575 chr14:65016802 C14orf50 -0.64 -4.53 -0.38 1.36e-5 N-glycan levels; TGCT cis rs4372836 0.964 rs11683296 chr2:28925404 A/G cg09522027 chr2:28974177 PPP1CB 0.58 4.83 0.4 3.88e-6 Body mass index; TGCT cis rs853679 0.567 rs7740429 chr6:28399246 G/A cg18815343 chr6:28367644 ZSCAN12 -0.5 -4.56 -0.38 1.19e-5 Depression; TGCT trans rs1814175 0.791 rs10769625 chr11:49869887 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs17490626 0.533 rs12771890 chr10:71189483 T/A cg12610070 chr10:71211762 TSPAN15 -0.59 -6.86 -0.52 2.87e-10 Thrombosis; TGCT cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs3845702 0.736 rs115569960 chr2:180848214 C/T cg01881094 chr2:180872142 CWC22 1.04 6.62 0.51 9.91e-10 Schizophrenia; TGCT cis rs8179 0.593 rs17164683 chr7:92286980 C/T cg15732164 chr7:92237376 CDK6 -0.29 -4.98 -0.41 2.05e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs1218582 0.740 rs1977879 chr1:154879743 G/A cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs7267979 0.833 rs4619688 chr20:25244101 C/G cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.649 rs139540 chr22:42178040 C/T cg17554472 chr22:41940697 POLR3H -0.44 -4.58 -0.38 1.13e-5 Vitiligo; TGCT cis rs1799949 0.894 rs36062488 chr17:41337472 C/T cg05368731 chr17:41323189 NBR1 -1.06 -12.0 -0.73 1.76e-22 Menopause (age at onset); TGCT cis rs17767294 0.541 rs72845044 chr6:27572479 G/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Parkinson's disease; TGCT cis rs559928 0.576 rs750832 chr11:64163302 C/T cg12453748 chr11:64085041 PRDX5;TRMT112 -0.56 -4.82 -0.4 4.17e-6 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs2730245 0.636 rs710421 chr7:158668575 T/C cg24397884 chr7:158709396 WDR60 0.35 4.45 0.37 1.87e-5 Height; TGCT cis rs1348850 0.567 rs7605609 chr2:178534942 C/G cg22681709 chr2:178499509 PDE11A -0.46 -5.95 -0.47 2.58e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs26868 0.816 rs26873 chr16:2247362 C/T cg26873644 chr16:2260806 C16orf79 -0.24 -4.67 -0.39 7.57e-6 Height; TGCT cis rs73198271 0.710 rs3827808 chr8:8679357 A/T cg06671706 chr8:8559999 CLDN23 -0.36 -4.52 -0.38 1.45e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT trans rs208520 0.955 rs28684412 chr6:66979430 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs1801251 1.000 rs12478564 chr2:233598340 C/T cg25237894 chr2:233734115 C2orf82 0.33 6.02 0.48 1.82e-8 Coronary artery disease; TGCT cis rs3733585 0.699 rs6449178 chr4:9968684 A/G cg00071950 chr4:10020882 SLC2A9 0.55 6.5 0.5 1.79e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7267979 0.509 rs6115218 chr20:25566485 A/G cg16686733 chr20:25566563 NINL 0.84 8.95 0.63 4.19e-15 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs11096990 0.656 rs9993224 chr4:39300198 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.47 -0.37 1.75e-5 Cognitive function; TGCT cis rs17826219 0.706 rs609472 chr17:28951427 T/C cg04154034 chr17:28927549 LRRC37B2 0.82 5.01 0.41 1.85e-6 Body mass index; TGCT cis rs838147 0.507 rs692854 chr19:49209464 C/A cg13540341 chr19:49222985 MAMSTR -0.37 -4.92 -0.4 2.69e-6 Dietary macronutrient intake; TGCT cis rs1215050 0.765 rs471500 chr4:98714820 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1552244 0.832 rs17050674 chr3:10027258 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.44 -6.38 -0.5 3.16e-9 Alzheimer's disease; TGCT cis rs4285028 0.948 rs12637351 chr3:121694412 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.77 6.5 0.5 1.78e-9 Multiple sclerosis; TGCT cis rs910316 0.789 rs175457 chr14:75584507 C/T cg08847533 chr14:75593920 NEK9 -0.85 -8.54 -0.61 4.13e-14 Height; TGCT cis rs12477438 0.798 rs9679602 chr2:99577827 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.86 8.65 0.61 2.22e-14 Chronic sinus infection; TGCT cis rs586688 0.582 rs662852 chr1:201672614 T/G cg07139329 chr1:201708558 NAV1 -0.5 -5.19 -0.42 8.37e-7 Obesity-related traits; TGCT cis rs79349575 0.749 rs46521 chr17:46988529 A/G cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT cis rs2229238 0.826 rs111742980 chr1:154508764 T/A cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs7954584 0.626 rs12809676 chr12:122442381 C/A cg13699009 chr12:122356056 WDR66 0.27 5.2 0.42 7.87e-7 Mean corpuscular volume; TGCT trans rs66573146 1.000 rs7686168 chr4:6986057 C/A cg07817883 chr1:32538562 TMEM39B 1.66 8.29 0.6 1.56e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs7666738 0.830 rs10050008 chr4:99025313 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.652 rs673821 chr11:68678718 G/T cg06112835 chr11:68658793 MRPL21 0.43 7.25 0.55 3.9e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9659323 1.000 rs12073056 chr1:119508400 C/T cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.41e-6 Body mass index; TGCT cis rs6815814 0.948 rs73236649 chr4:38873332 C/T cg02016764 chr4:38805732 TLR1 -0.39 -5.6 -0.45 1.3e-7 Breast cancer; TGCT cis rs4969178 0.600 rs4969183 chr17:76393372 A/G cg05887092 chr17:76393375 PGS1 0.22 4.66 0.39 8.19e-6 HDL cholesterol levels; TGCT cis rs6952808 0.825 rs4236277 chr7:1942270 C/T cg04267008 chr7:1944627 MAD1L1 -0.38 -4.93 -0.4 2.55e-6 Bipolar disorder and schizophrenia; TGCT cis rs1451375 0.959 rs1451373 chr7:50622606 A/G cg18232548 chr7:50535776 DDC 0.43 6.8 0.52 3.98e-10 Malaria; TGCT cis rs854765 0.647 rs712268 chr17:18025744 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.57 0.56 7.33e-12 Total body bone mineral density; TGCT cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs7772486 0.727 rs10447449 chr6:146138707 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.88 0.4 3.23e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs16867321 0.950 rs1919155 chr2:181457053 T/C cg23363182 chr2:181467187 NA -0.39 -5.47 -0.44 2.38e-7 Obesity; TGCT cis rs4975709 0.610 rs4975704 chr5:1859807 C/A cg07747251 chr5:1868357 NA 0.38 5.28 0.43 5.55e-7 Cardiovascular disease risk factors; TGCT cis rs7937682 0.883 rs490492 chr11:111465150 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs1218582 0.741 rs2335407 chr1:154843347 A/G cg24250549 chr1:154909240 PMVK -0.53 -4.92 -0.4 2.64e-6 Prostate cancer; TGCT cis rs6121246 0.738 rs6121242 chr20:30410877 T/C cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs2230307 0.536 rs490669 chr1:100484430 C/T cg24955406 chr1:100503596 HIAT1 0.74 4.83 0.4 4e-6 Carotid intima media thickness; TGCT cis rs10789491 1.000 rs2218191 chr1:47130628 C/T cg15501359 chr1:47185051 KIAA0494 0.78 7.94 0.58 1.05e-12 Response to hepatitis C treatment; TGCT cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg07636037 chr3:49044803 WDR6 0.7 7.73 0.57 3.24e-12 Parkinson's disease; TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg24675658 chr1:53192096 ZYG11B -0.75 -9.11 -0.63 1.78e-15 Monocyte count; TGCT cis rs25422 0.878 rs55894300 chr6:118982076 T/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.71 -0.39 6.4e-6 Renal cell carcinoma; TGCT cis rs3733585 0.683 rs6449140 chr4:9936437 G/C cg00071950 chr4:10020882 SLC2A9 -0.63 -7.56 -0.56 7.61e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7226408 0.779 rs72896202 chr18:34766272 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs12477438 0.520 rs34252185 chr2:99737646 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.22 0.85 7.28e-37 Chronic sinus infection; TGCT cis rs9814567 0.762 rs13075332 chr3:134329836 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.82 6.65 0.51 8.45e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7524258 0.868 rs11120885 chr1:7306755 C/G cg04342483 chr1:7259290 CAMTA1 -0.31 -4.52 -0.38 1.43e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs1005277 0.579 rs2021649 chr10:38392122 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2153535 0.580 rs1120392 chr6:8487053 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs3806843 0.576 rs246072 chr5:140320426 C/T cg07102913 chr5:140593443 PCDHB13 -0.46 -4.65 -0.39 8.2e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1005277 0.579 rs2474599 chr10:38438939 A/G cg13531842 chr10:38383804 ZNF37A -0.39 -4.64 -0.38 8.78e-6 Extrinsic epigenetic age acceleration; TGCT cis rs12142240 0.698 rs66972124 chr1:46807445 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs559406 0.501 rs2542160 chr18:12789246 C/G cg23598886 chr18:12777645 NA 0.36 4.52 0.38 1.45e-5 Psoriasis; TGCT cis rs634534 0.622 rs1308733 chr11:65720841 T/C cg02427764 chr11:65769310 BANF1;EIF1AD -0.54 -5.2 -0.42 8.02e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7727544 0.904 rs7736102 chr5:131604257 G/A cg24060327 chr5:131705240 SLC22A5 -0.6 -6.4 -0.5 2.87e-9 Blood metabolite levels; TGCT cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg06896619 chr17:61851486 DDX42;CCDC47 0.49 4.47 0.37 1.71e-5 Prudent dietary pattern; TGCT cis rs1552244 0.816 rs17050701 chr3:10041554 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg26818010 chr10:134567672 INPP5A -0.38 -5.19 -0.42 8.5e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg18305652 chr10:134549665 INPP5A 0.34 5.75 0.46 6.52e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6570726 0.967 rs9497316 chr6:145792387 G/T cg23711669 chr6:146136114 FBXO30 -0.69 -6.34 -0.49 3.95e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7523273 0.568 rs1318653 chr1:208014922 C/T cg22525895 chr1:207977042 MIR29B2 0.39 5.63 0.45 1.16e-7 Schizophrenia; TGCT cis rs9341808 0.718 rs11962614 chr6:80823306 A/T cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs6835098 0.828 rs28612521 chr4:174085294 G/A cg08422745 chr4:174089978 GALNT7 -0.94 -11.2 -0.71 1.48e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT trans rs1814175 0.645 rs28441045 chr11:50048971 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs3743266 0.507 rs9630426 chr15:60739053 C/T cg18480781 chr15:60294291 NA 0.63 5.01 0.41 1.81e-6 Menarche (age at onset); TGCT cis rs12360000 0.577 rs10430757 chr10:1906265 C/T cg26364871 chr10:1889757 NA 0.38 4.54 0.38 1.3e-5 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs9457247 1.000 rs398278 chr6:167388169 A/G cg23791538 chr6:167370224 RNASET2 -0.53 -5.18 -0.42 8.67e-7 Crohn's disease; TGCT cis rs67072384 0.818 rs6592483 chr11:72463974 A/G cg03713592 chr11:72463424 ARAP1 -0.9 -4.87 -0.4 3.33e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs10504229 1.000 rs66479724 chr8:58188309 T/G cg08280861 chr8:58055591 NA 0.34 4.62 0.38 9.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs3771570 1.000 rs73004354 chr2:242356239 G/T cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.97e-10 Prostate cancer; TGCT cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg20203395 chr5:56204925 C5orf35 -0.62 -4.92 -0.4 2.68e-6 Initial pursuit acceleration; TGCT cis rs2013441 1.000 rs8074047 chr17:20176703 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.5 -0.37 1.55e-5 Obesity-related traits; TGCT trans rs1496653 0.602 rs34916096 chr3:23443636 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs17125944 0.505 rs17125746 chr14:53236079 C/T cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs12477438 0.520 rs2632276 chr2:99779655 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 12.88 0.76 1.27e-24 Chronic sinus infection; TGCT cis rs9611565 0.512 rs139572 chr22:42214532 C/T cg06634786 chr22:41940651 POLR3H -0.86 -8.01 -0.58 7.16e-13 Vitiligo; TGCT cis rs727505 1.000 rs988699 chr7:124409814 C/T cg23710748 chr7:124431027 NA -0.27 -4.71 -0.39 6.45e-6 Lewy body disease; TGCT cis rs2663905 0.611 rs1509558 chr15:81391244 C/T cg09888468 chr15:81410853 NA -0.6 -4.9 -0.4 2.97e-6 QT interval (drug interaction); TGCT cis rs7447593 0.518 rs4074995 chr5:176797343 C/T cg06060754 chr5:176797920 RGS14 0.62 11.28 0.71 9.83e-21 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs34526934 0.608 rs7606110 chr2:177028551 T/C cg00278547 chr2:177037212 HOXD3 -0.4 -4.98 -0.41 2.09e-6 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs9868809 0.505 rs28657585 chr3:48736216 A/T cg00383909 chr3:49044727 WDR6 1.05 6.17 0.48 8.74e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs11785400 1.000 rs13265663 chr8:143732255 A/C cg24634471 chr8:143751801 JRK 0.54 5.85 0.46 4.19e-8 Schizophrenia; TGCT cis rs72945132 0.598 rs61887432 chr11:70239065 A/C cg00319359 chr11:70116639 PPFIA1 1.0 7.12 0.54 7.76e-11 Coronary artery disease; TGCT cis rs66573146 1.000 rs66712119 chr4:6965428 A/T cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs11690935 0.632 rs62184165 chr2:172558328 A/G cg13550731 chr2:172543902 DYNC1I2 0.69 6.09 0.48 1.33e-8 Schizophrenia; TGCT cis rs12971120 0.947 rs8084109 chr18:72168312 T/A cg26446133 chr18:72167187 CNDP2 -0.4 -7.7 -0.57 3.64e-12 Refractive error; TGCT cis rs1205863 0.831 rs1205854 chr6:11942638 A/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs7666738 0.830 rs11097582 chr4:98772201 G/A cg18180107 chr4:99064573 C4orf37 0.53 5.05 0.41 1.51e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1153858 1.000 rs7179743 chr15:45638331 G/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs6121246 0.567 rs6087701 chr20:30217708 A/C cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs7513165 0.542 rs4951317 chr1:204161507 C/T cg04791601 chr1:204159016 NA 0.27 5.78 0.46 5.74e-8 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs4409675 0.576 rs3766396 chr1:28221554 C/T cg23691781 chr1:28212827 C1orf38 -0.26 -5.32 -0.43 4.68e-7 Corneal astigmatism; TGCT cis rs11190604 1.000 rs12355721 chr10:102244911 C/T cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2708977 0.966 rs749027 chr2:97203137 A/C cg01950434 chr2:97203154 ARID5A -0.69 -6.36 -0.5 3.5e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs939658 0.776 rs35904425 chr15:79444567 G/A cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs4455778 0.580 rs10257863 chr7:49092400 C/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.52 0.61 4.51e-14 Platelet count; TGCT cis rs7666738 0.830 rs1593569 chr4:99017485 C/G cg17366294 chr4:99064904 C4orf37 0.7 7.34 0.55 2.41e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7833790 0.724 rs1054078 chr8:82712153 A/G cg27398817 chr8:82754497 SNX16 -0.67 -5.34 -0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs6714710 0.603 rs7421146 chr2:98552271 G/C cg26665480 chr2:98280029 ACTR1B 0.66 6.26 0.49 5.84e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs78487399 0.808 rs6544668 chr2:43732488 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.84 -0.4 3.79e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg20637647 chr7:64974828 NA 0.84 4.85 0.4 3.63e-6 Diabetic kidney disease; TGCT trans rs10506458 1.000 rs12580997 chr12:63433420 G/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.62 -0.56 5.8e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs59107033 0.607 rs7635110 chr3:123124137 T/C cg04890266 chr3:123102914 ADCY5 -0.38 -5.29 -0.43 5.31e-7 Lymphocyte counts; TGCT cis rs7267979 0.868 rs6138546 chr20:25216534 G/A cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.98e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3772130 0.962 rs1318472 chr3:121556899 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs1801251 0.835 rs1446310 chr2:233683245 G/C cg08000102 chr2:233561755 GIGYF2 -0.57 -5.89 -0.47 3.38e-8 Coronary artery disease; TGCT cis rs7829975 0.659 rs4382480 chr8:8721473 C/T cg08975724 chr8:8085496 FLJ10661 0.55 5.2 0.42 7.94e-7 Mood instability; TGCT cis rs1865760 1.000 rs2071301 chr6:25914263 G/T cg16482183 chr6:26056742 HIST1H1C 0.54 4.95 0.41 2.39e-6 Height; TGCT trans rs3780486 0.846 rs913214 chr9:33135085 G/A cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT cis rs524281 0.861 rs485857 chr11:65959519 A/G cg00563793 chr11:65837595 PACS1 0.52 4.57 0.38 1.18e-5 Electroencephalogram traits; TGCT cis rs904251 0.772 rs2776906 chr6:37431757 A/G cg08126542 chr6:37504118 NA -0.4 -4.66 -0.39 7.87e-6 Cognitive performance; TGCT cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9604529 0.557 rs61967979 chr13:114743190 C/T cg13259177 chr13:114761607 RASA3 -0.28 -4.79 -0.4 4.66e-6 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs9858542 0.953 rs7622302 chr3:49547561 T/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs67072384 0.892 rs11235578 chr11:72452970 G/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs752010 0.668 rs10890147 chr1:42089725 A/T cg06885757 chr1:42089581 HIVEP3 0.31 5.84 0.46 4.24e-8 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs36051895 0.626 rs10815149 chr9:5063701 T/C cg02405213 chr9:5042618 JAK2 -0.8 -11.53 -0.72 2.44e-21 Pediatric autoimmune diseases; TGCT cis rs13082711 0.516 rs1388785 chr3:27371843 T/C cg02860705 chr3:27208620 NA -0.31 -4.61 -0.38 9.69e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.580 rs4451187 chr6:8473910 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.3e-6 Motion sickness; TGCT cis rs734999 0.545 rs6666430 chr1:2698950 G/A cg18854424 chr1:2615690 NA 0.45 5.01 0.41 1.82e-6 Ulcerative colitis; TGCT cis rs7523273 0.606 rs1474742 chr1:207976666 A/C cg22525895 chr1:207977042 MIR29B2 0.5 8.58 0.61 3.27e-14 Schizophrenia; TGCT cis rs11690935 0.959 rs10497374 chr2:172640623 A/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs4808199 0.948 rs968525 chr19:19459215 C/T cg03709012 chr19:19516395 GATAD2A 0.82 6.56 0.51 1.3e-9 Nonalcoholic fatty liver disease; TGCT cis rs896854 0.654 rs896846 chr8:95972453 G/A cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.57e-9 Type 2 diabetes; TGCT trans rs7819412 0.511 rs10108511 chr8:11435516 T/C cg06636001 chr8:8085503 FLJ10661 -0.76 -6.97 -0.53 1.68e-10 Triglycerides; TGCT cis rs1215050 0.791 rs7434393 chr4:98768576 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9916302 0.861 rs644173 chr17:37430519 T/C cg15445000 chr17:37608096 MED1 0.31 4.48 0.37 1.66e-5 Glomerular filtration rate (creatinine); TGCT cis rs919433 0.680 rs1961558 chr2:198487278 C/T cg00792783 chr2:198669748 PLCL1 0.5 4.67 0.39 7.56e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs778371 0.834 rs778363 chr2:233778896 A/G cg08000102 chr2:233561755 GIGYF2 -0.49 -4.58 -0.38 1.1e-5 Schizophrenia; TGCT cis rs6964587 1.000 rs1859113 chr7:91679887 T/C cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT trans rs6089829 0.925 rs6062396 chr20:61667949 T/C cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7666738 0.800 rs13106995 chr4:99028790 A/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12579753 0.879 rs35087297 chr12:82133398 C/T cg21231944 chr12:82153410 PPFIA2 -0.36 -4.7 -0.39 6.72e-6 Resting heart rate; TGCT cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.79e-6 Obesity-related traits; TGCT cis rs9443645 0.901 rs9448588 chr6:79590061 T/G cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs873917 0.577 rs784612 chr1:40122939 T/C cg18438793 chr1:40149837 HPCAL4 0.53 4.72 0.39 6.17e-6 Amyotrophic lateral sclerosis; TGCT cis rs7666738 0.819 rs13120307 chr4:99036100 A/C cg17366294 chr4:99064904 C4orf37 0.74 7.59 0.56 6.7e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7178572 0.568 rs3743478 chr15:77400388 T/C cg22256960 chr15:77711686 NA -0.85 -8.66 -0.61 2.08e-14 Type 2 diabetes; TGCT cis rs35306767 0.807 rs72778228 chr10:938435 A/G cg20503657 chr10:835505 NA 0.8 11.88 0.73 3.41e-22 Eosinophil percentage of granulocytes; TGCT cis rs1008375 0.966 rs28750296 chr4:17685826 A/T cg18681998 chr4:17616180 MED28 0.92 10.51 0.69 7.15e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs585510 1 rs585510 chr12:121000133 A/G cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 Reticulocyte fraction of red cells; TGCT cis rs10057188 0.903 rs1441711 chr5:77910931 T/C cg07379703 chr5:78279424 ARSB -0.21 -4.79 -0.4 4.64e-6 Pulse pressure; TGCT cis rs7772486 0.790 rs9403750 chr6:146167762 G/A cg05347473 chr6:146136440 FBXO30 0.51 4.77 0.39 5.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4819052 0.851 rs1999335 chr21:46670613 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.82 7.26 0.55 3.65e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12220898 0.679 rs4838483 chr10:50481870 G/A cg09603381 chr10:49954066 WDFY4 0.39 4.48 0.37 1.68e-5 Inflammatory biomarkers; TGCT cis rs554111 0.656 rs10916930 chr1:21395357 C/T cg01072550 chr1:21505969 NA -0.37 -5.64 -0.45 1.1e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs6912958 0.525 rs242262 chr6:88018057 A/C cg08069147 chr6:88032118 GJB7;C6orf162 0.69 7.11 0.54 7.98e-11 Monocyte percentage of white cells; TGCT cis rs7267979 0.565 rs4815437 chr20:25584788 C/G cg03522245 chr20:25566470 NINL -0.44 -4.57 -0.38 1.18e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1903068 1.000 rs1903068 chr4:56008477 A/G cg16572876 chr4:56024045 NA 0.44 5.1 0.42 1.23e-6 Endometriosis; TGCT cis rs1153858 0.945 rs2467854 chr15:45701597 A/G cg14582100 chr15:45693742 SPATA5L1 0.47 5.62 0.45 1.22e-7 Homoarginine levels; TGCT cis rs2439831 0.867 rs12323999 chr15:43683115 T/A cg27015174 chr15:43622946 ADAL;LCMT2 0.88 6.11 0.48 1.19e-8 Lung cancer in ever smokers; TGCT cis rs8141529 0.748 rs6005936 chr22:29289250 T/C cg02153584 chr22:29168773 CCDC117 0.66 5.19 0.42 8.5e-7 Lymphocyte counts; TGCT cis rs9291683 0.588 rs13113730 chr4:10017628 C/T cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Bone mineral density; TGCT cis rs3820068 0.581 rs16851855 chr1:15930869 G/A cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg22105103 chr4:187893119 NA 0.31 4.44 0.37 1.98e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg04944784 chr2:26401820 FAM59B -0.73 -5.95 -0.47 2.61e-8 Gut microbiome composition (summer); TGCT cis rs1552244 0.882 rs17081288 chr3:10042113 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs12497850 0.931 rs7430198 chr3:48988760 T/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 2.97e-7 Parkinson's disease; TGCT cis rs12142240 0.698 rs17357759 chr1:46832534 A/G cg00530320 chr1:46809349 NSUN4 0.33 7.21 0.54 4.73e-11 Menopause (age at onset); TGCT cis rs7826238 0.502 rs10503377 chr8:8378422 C/T cg15556689 chr8:8085844 FLJ10661 0.71 6.11 0.48 1.21e-8 Systolic blood pressure; TGCT cis rs763014 0.593 rs28455838 chr16:681966 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.42 -0.6 7.67e-14 Height; TGCT cis rs2075371 1.000 rs2505 chr7:133979552 C/T cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs651907 0.557 rs7651406 chr3:101393296 C/T cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.08 -0.54 9.37e-11 Colorectal cancer; TGCT cis rs6964587 1.000 rs10228800 chr7:91610111 T/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs2836974 0.666 rs11910705 chr21:40685604 C/T cg06238570 chr21:40685208 BRWD1 -0.82 -9.01 -0.63 3.07e-15 Cognitive function; TGCT cis rs4851266 0.966 rs1160545 chr2:100832269 C/T cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs12762955 0.561 rs7076107 chr10:1043647 T/C cg26597838 chr10:835615 NA -0.47 -6.22 -0.49 7.03e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs5750830 0.569 rs5750809 chr22:39791491 T/G cg05872129 chr22:39784769 NA -1.02 -11.22 -0.71 1.32e-20 Intelligence (multi-trait analysis); TGCT cis rs1056107 0.898 rs10733586 chr9:114992183 A/G cg02332936 chr9:115140584 NA -0.25 -4.46 -0.37 1.79e-5 Colorectal cancer; TGCT cis rs6665290 0.904 rs1045287 chr1:227178962 C/T cg10327440 chr1:227177885 CDC42BPA 1.0 20.45 0.88 1.56e-41 Myeloid white cell count; TGCT cis rs9611565 0.694 rs5758324 chr22:41787950 G/T cg13695892 chr22:41940480 POLR3H -0.85 -8.37 -0.6 1.01e-13 Vitiligo; TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.67 0.39 7.57e-6 Prudent dietary pattern; TGCT cis rs7647973 0.731 rs13084037 chr3:49214066 G/A cg06212747 chr3:49208901 KLHDC8B 0.62 4.75 0.39 5.59e-6 Menarche (age at onset); TGCT cis rs10191773 0.535 rs56048537 chr2:113078467 G/T cg07905836 chr2:113190072 RGPD8;RGPD5 0.46 4.92 0.4 2.69e-6 Yeast infection; TGCT cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.51 0.65 1.95e-16 Cognitive function; TGCT trans rs6089829 0.962 rs4809462 chr20:61661560 A/G cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs4851266 1.000 rs1465801 chr2:100836060 C/T cg22139774 chr2:100720529 AFF3 -0.34 -5.22 -0.42 7.28e-7 Educational attainment; TGCT cis rs12210905 0.688 rs12374649 chr6:27343726 C/T cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs6912958 0.781 rs985764 chr6:88215206 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs6582630 0.519 rs8189623 chr12:38351436 G/A cg13010199 chr12:38710504 ALG10B 0.58 4.52 0.38 1.41e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs8177253 0.965 rs8177260 chr3:133480458 T/A cg08048268 chr3:133502702 NA -0.66 -10.0 -0.67 1.29e-17 Iron status biomarkers; TGCT cis rs651907 0.557 rs3864012 chr3:101397623 T/C cg12386194 chr3:101231763 SENP7 0.51 5.04 0.41 1.61e-6 Colorectal cancer; TGCT cis rs931127 0.719 rs2127507 chr11:65454430 A/G cg17480646 chr11:65405466 SIPA1 -0.43 -5.74 -0.46 6.76e-8 Systemic lupus erythematosus; TGCT cis rs7474896 0.583 rs12776092 chr10:38015795 G/C cg13720705 chr10:37990370 NA 0.33 4.81 0.4 4.21e-6 Obesity (extreme); TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg22166914 chr1:53195759 ZYG11B 0.36 5.96 0.47 2.45e-8 Monocyte count; TGCT cis rs28595532 0.920 rs116428408 chr4:119758514 G/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7678296 0.649 rs4585313 chr4:37240236 C/T cg18431856 chr4:37245254 KIAA1239 -0.71 -4.75 -0.39 5.62e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs9818758 0.556 rs9872660 chr3:49378832 G/T cg00383909 chr3:49044727 WDR6 0.7 4.75 0.39 5.48e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7845219 0.544 rs4735331 chr8:95917958 C/T cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs9467773 1.000 rs6922824 chr6:26553815 C/G cg09904177 chr6:26538194 HMGN4 -0.63 -6.33 -0.49 4.08e-9 Intelligence (multi-trait analysis); TGCT cis rs539096 0.692 rs7549094 chr1:44213178 C/A cg12908607 chr1:44402522 ARTN -0.63 -7.43 -0.56 1.52e-11 Intelligence (multi-trait analysis); TGCT cis rs6032067 0.636 rs17335251 chr20:43902946 T/A cg16667508 chr20:43936853 MATN4;RBPJL -0.47 -6.81 -0.52 3.84e-10 Blood protein levels; TGCT cis rs453301 0.500 rs7015336 chr8:8830720 G/A cg15556689 chr8:8085844 FLJ10661 0.66 5.33 0.43 4.56e-7 Joint mobility (Beighton score); TGCT cis rs17102423 0.652 rs4902361 chr14:65548470 G/T cg11161011 chr14:65562177 MAX -0.47 -6.4 -0.5 2.89e-9 Obesity-related traits; TGCT cis rs7762018 0.760 rs28660085 chr6:170101996 C/G cg02388276 chr6:170744041 NA -0.23 -4.45 -0.37 1.89e-5 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs2243480 1.000 rs13235972 chr7:65883605 C/T cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs8078723 1.000 rs56922390 chr17:38157021 C/G cg17467752 chr17:38218738 THRA 0.55 5.34 0.43 4.24e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT trans rs1005277 0.579 rs2474608 chr10:38457109 C/T cg27523141 chr10:43048294 ZNF37B 0.74 8.61 0.61 2.7e-14 Extrinsic epigenetic age acceleration; TGCT cis rs9640161 0.636 rs56190213 chr7:150025720 T/C cg10018233 chr7:150070692 REPIN1 0.32 4.58 0.38 1.1e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs9914544 0.583 rs35783872 chr17:18748820 A/C cg26378065 chr17:18585709 ZNF286B 0.52 4.54 0.38 1.32e-5 Educational attainment (years of education); TGCT cis rs12134245 0.747 rs11164912 chr1:92005191 A/T cg25838465 chr1:92012736 NA -0.43 -6.93 -0.53 2.04e-10 Breast cancer; TGCT cis rs12477438 0.520 rs2309581 chr2:99784292 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -1.03 -12.73 -0.75 2.93e-24 Chronic sinus infection; TGCT cis rs769267 0.895 rs2916074 chr19:19530270 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.59 4.99 0.41 2.04e-6 Tonsillectomy; TGCT cis rs2075371 0.932 rs1035328 chr7:133978419 T/C cg11752832 chr7:134001865 SLC35B4 0.72 6.62 0.51 9.63e-10 Mean platelet volume; TGCT cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg17971929 chr21:40555470 PSMG1 0.98 9.61 0.65 1.14e-16 Cognitive function; TGCT cis rs4819852 0.752 rs2238783 chr22:19972452 C/G cg07821417 chr22:19972146 ARVCF 0.19 4.56 0.38 1.2e-5 Pulse pressure; TGCT cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg03517284 chr6:25882590 NA -0.64 -5.78 -0.46 5.8e-8 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.501 rs2836984 chr21:40700949 A/C cg06238570 chr21:40685208 BRWD1 -0.64 -6.56 -0.51 1.34e-9 Menarche (age at onset); TGCT cis rs9486719 0.857 rs2983897 chr6:97033780 C/T cg06623918 chr6:96969491 KIAA0776 -0.98 -9.95 -0.67 1.64e-17 Migraine;Coronary artery disease; TGCT cis rs1008375 0.931 rs7435102 chr4:17571480 C/G cg10189774 chr4:17578691 LAP3 0.67 5.87 0.47 3.77e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs854765 0.663 rs9915248 chr17:17747514 C/T cg04398451 chr17:18023971 MYO15A 0.3 4.6 0.38 1.04e-5 Total body bone mineral density; TGCT cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9346649 0.583 rs4708642 chr6:168491500 G/A cg02770688 chr6:168491649 NA 0.34 6.05 0.48 1.6e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs617219 0.671 rs12189188 chr5:78552312 C/T cg23514016 chr5:78407564 BHMT 0.34 5.09 0.42 1.29e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9393777 1.000 rs9393777 chr6:26942027 T/C cg18364779 chr6:26104403 HIST1H4C -0.65 -4.59 -0.38 1.06e-5 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.582 rs4919661 chr10:104358403 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.89 7.32 0.55 2.74e-11 Platelet count; TGCT cis rs7772486 0.727 rs4896843 chr6:146063451 T/C cg13319975 chr6:146136371 FBXO30 0.56 4.95 0.41 2.37e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs42648 0.596 rs194507 chr7:89843560 A/C cg25739043 chr7:89950458 NA 0.47 4.51 0.38 1.47e-5 Homocysteine levels; TGCT cis rs2153535 0.580 rs7341381 chr6:8470537 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs5758343 1 rs5758343 chr22:41816652 A/T cg17554472 chr22:41940697 POLR3H 0.52 5.31 0.43 4.84e-7 Allergic disease (asthma, hay fever or eczema); TGCT cis rs74054849 0.850 rs55764623 chr1:15954383 G/A cg05660106 chr1:15850417 CASP9 0.86 4.48 0.37 1.68e-5 Alcoholic chronic pancreatitis; TGCT cis rs62380364 0.626 rs11749912 chr5:88065628 A/G cg24804195 chr5:87968844 LOC645323 -0.57 -5.45 -0.44 2.6e-7 Intelligence (multi-trait analysis); TGCT cis rs911555 0.755 rs2756122 chr14:103983033 C/G cg12935359 chr14:103987150 CKB -0.37 -5.05 -0.41 1.55e-6 Intelligence (multi-trait analysis); TGCT cis rs1008375 1.000 rs56974987 chr4:17627856 G/A cg18681998 chr4:17616180 MED28 1.02 11.4 0.72 4.89e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10206020 0.921 rs11884956 chr2:1566426 A/G cg12573674 chr2:1569213 NA -0.5 -5.49 -0.44 2.21e-7 IgG glycosylation; TGCT cis rs6725041 0.532 rs12623803 chr2:213201642 G/C cg20637307 chr2:213403960 ERBB4 -0.53 -4.49 -0.37 1.63e-5 QT interval (ambient particulate matter interaction); TGCT cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg22029157 chr1:209979665 IRF6 0.76 6.24 0.49 6.3e-9 Cleft lip with or without cleft palate; TGCT cis rs10791097 0.694 rs10791103 chr11:130757161 G/A cg12179176 chr11:130786555 SNX19 0.84 10.46 0.68 9.82e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs908922 0.676 rs477621 chr1:152486252 T/C cg20991723 chr1:152506922 NA 0.47 6.5 0.5 1.73e-9 Hair morphology; TGCT cis rs7100689 0.542 rs10887869 chr10:82194689 A/G cg00277334 chr10:82204260 NA -0.41 -5.12 -0.42 1.15e-6 Post bronchodilator FEV1; TGCT cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.82 9.44 0.65 2.93e-16 Menarche (age at onset); TGCT cis rs6088580 0.609 rs6059845 chr20:33036500 G/A cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs35306767 0.909 rs12264390 chr10:959111 T/C cg26597838 chr10:835615 NA 0.66 9.01 0.63 3.04e-15 Eosinophil percentage of granulocytes; TGCT cis rs4595586 0.545 rs12827197 chr12:39404362 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs56116382 0.604 rs9858428 chr3:49877585 G/T cg07636037 chr3:49044803 WDR6 -0.96 -4.5 -0.37 1.52e-5 Intelligence (multi-trait analysis);High light scatter reticulocyte count; TGCT cis rs6938 0.618 rs1133323 chr15:75212225 C/T cg09165964 chr15:75287851 SCAMP5 0.53 4.97 0.41 2.2e-6 Breast cancer; TGCT cis rs4304924 0.500 rs7339081 chr13:79235501 A/G cg01819759 chr13:79234251 RNF219 0.9 8.32 0.6 1.36e-13 Large artery stroke; TGCT cis rs3087591 1.000 rs2051506 chr17:29699860 T/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.28 -0.55 3.31e-11 Hip circumference; TGCT cis rs6987853 0.966 rs2923428 chr8:42388301 T/C cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs7666738 0.830 rs11940273 chr4:98979965 T/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs35146811 0.735 rs1138417 chr7:99807146 C/G cg00553149 chr7:99775558 STAG3;GPC2 -0.29 -4.43 -0.37 2.01e-5 Coronary artery disease; TGCT cis rs6714710 0.580 rs57681139 chr2:98454473 C/T cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs13326165 0.760 rs13075370 chr3:52399278 G/A cg27565382 chr3:53032988 SFMBT1 0.36 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs11098499 0.954 rs13107475 chr4:120393011 A/T cg09307838 chr4:120376055 NA 0.71 6.95 0.53 1.85e-10 Corneal astigmatism; TGCT trans rs1814175 0.541 rs12287397 chr11:49819799 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs7552404 1.000 rs4559448 chr1:76203456 A/G cg03433033 chr1:76189801 ACADM 0.82 9.74 0.66 5.46e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2589561 0.872 rs2440781 chr10:9051328 A/G cg08738443 chr10:8487762 NA -0.37 -4.74 -0.39 5.74e-6 Asthma; TGCT cis rs7552404 0.731 rs1689275 chr1:76409655 T/C cg10523679 chr1:76189770 ACADM -0.84 -7.83 -0.58 1.9e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg19536664 chr17:6899085 ALOX12 0.38 5.96 0.47 2.4e-8 Tonsillectomy; TGCT cis rs1552244 0.572 rs12107622 chr3:10171898 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.49 -0.44 2.22e-7 Alzheimer's disease; TGCT cis rs250677 0.522 rs17109208 chr5:148378475 G/A cg18129178 chr5:148520854 ABLIM3 -0.36 -4.74 -0.39 5.82e-6 Breast cancer; TGCT cis rs12477438 0.765 rs72957180 chr2:99694452 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs7208859 0.623 rs56095789 chr17:29060170 A/G cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1218582 0.600 rs72702224 chr1:154911689 G/A cg24250549 chr1:154909240 PMVK 0.47 4.5 0.37 1.55e-5 Prostate cancer; TGCT trans rs2469997 0.925 rs2447170 chr8:120361421 C/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs4665809 1.000 rs6546736 chr2:26293878 C/T cg27170947 chr2:26402098 FAM59B 0.39 4.46 0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs7565124 1.000 rs7570953 chr2:20255015 T/C cg00462460 chr2:20212509 MATN3 -0.45 -4.84 -0.4 3.73e-6 Major depressive disorder; TGCT cis rs25422 0.938 rs9489443 chr6:118886163 T/A cg07617317 chr6:118971624 C6orf204 0.51 5.46 0.44 2.44e-7 Renal cell carcinoma; TGCT cis rs7617480 0.616 rs7429596 chr3:48808531 T/C cg07636037 chr3:49044803 WDR6 0.79 6.43 0.5 2.54e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs832540 0.898 rs702680 chr5:56220382 T/C cg12311346 chr5:56204834 C5orf35 -0.48 -5.02 -0.41 1.76e-6 Coronary artery disease; TGCT cis rs62064224 0.791 rs2344977 chr17:30720573 C/G cg09324608 chr17:30823087 MYO1D 0.26 5.3 0.43 5.19e-7 Schizophrenia; TGCT cis rs9322193 0.923 rs4869812 chr6:149990583 A/G cg13206674 chr6:150067644 NUP43 0.53 4.56 0.38 1.23e-5 Lung cancer; TGCT cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467711 0.516 rs1324087 chr6:25841408 A/G cg03264133 chr6:25882463 NA 0.67 4.47 0.37 1.76e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs4148883 0.504 rs9307238 chr4:100136182 A/G cg12011299 chr4:100065546 ADH4 -0.36 -5.17 -0.42 8.99e-7 Alcohol dependence; TGCT cis rs11098499 0.863 rs10019674 chr4:120443489 C/T cg09307838 chr4:120376055 NA -0.68 -6.44 -0.5 2.39e-9 Corneal astigmatism; TGCT cis rs67311347 1.000 rs6762997 chr3:40478151 C/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs9611519 0.964 rs2179744 chr22:41621714 G/A cg03806693 chr22:41940476 POLR3H -0.67 -6.4 -0.5 2.9e-9 Neuroticism; TGCT cis rs7975161 0.630 rs4964257 chr12:104633262 T/C cg25273343 chr12:104657179 TXNRD1 -0.35 -4.83 -0.4 3.87e-6 Toenail selenium levels; TGCT cis rs12200560 0.505 rs211164 chr6:97068140 G/T cg06623918 chr6:96969491 KIAA0776 0.57 4.83 0.4 3.93e-6 Coronary heart disease; TGCT cis rs2839186 0.749 rs62226489 chr21:47710519 T/C cg13732083 chr21:47605072 C21orf56 0.34 4.48 0.37 1.68e-5 Testicular germ cell tumor; TGCT cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs5769707 0.706 rs2071903 chr22:50034517 G/A cg06623630 chr22:50017776 C22orf34 -0.26 -4.53 -0.38 1.34e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs910316 0.967 rs10246 chr14:75544470 T/A cg08847533 chr14:75593920 NEK9 0.96 10.53 0.69 6.43e-19 Height; TGCT cis rs9399135 0.967 rs4142299 chr6:135377186 G/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs4780401 0.632 rs8055462 chr16:11834821 T/C cg01061890 chr16:11836724 TXNDC11 -0.63 -6.09 -0.48 1.32e-8 Rheumatoid arthritis; TGCT cis rs10540 1.000 rs71487292 chr11:486076 G/A cg03934478 chr11:495069 RNH1 0.33 5.08 0.42 1.33e-6 Body mass index; TGCT cis rs8070740 0.947 rs3809842 chr17:5329199 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.55 0.38 1.27e-5 Menopause (age at onset); TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg17178900 chr1:205818956 PM20D1 0.52 6.39 0.5 3.02e-9 Monocyte percentage of white cells; TGCT cis rs7119038 0.818 rs56043232 chr11:118648373 C/T cg19308663 chr11:118741387 NA 0.31 6.12 0.48 1.14e-8 Sjögren's syndrome; TGCT cis rs4925325 1.000 rs4925325 chr20:60514224 G/A cg13770153 chr20:60521292 NA 0.62 8.77 0.62 1.15e-14 Obesity-related traits; TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg21748317 chr7:158073589 PTPRN2 0.47 7.27 0.55 3.63e-11 Phosphorus levels; TGCT cis rs2486012 0.826 rs1008137 chr1:44420754 A/G cg12908607 chr1:44402522 ARTN -0.71 -5.84 -0.46 4.28e-8 Intelligence (multi-trait analysis); TGCT cis rs61990749 0.597 rs176955 chr14:78181220 C/T cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT trans rs1814175 0.935 rs10839317 chr11:49657228 A/C cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg03161606 chr19:29218774 NA 0.62 5.97 0.47 2.36e-8 Methadone dose in opioid dependence; TGCT cis rs12497850 0.897 rs6781790 chr3:49044767 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.4 -0.44 3.33e-7 Parkinson's disease; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT trans rs35851103 0.627 rs6601644 chr8:11847078 G/A cg15556689 chr8:8085844 FLJ10661 0.85 8.65 0.61 2.22e-14 Neuroticism; TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg09737314 chr17:6899359 ALOX12 0.49 5.16 0.42 9.71e-7 Tonsillectomy; TGCT cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg03806693 chr22:41940476 POLR3H -1.15 -12.98 -0.76 7.24e-25 Vitiligo; TGCT cis rs7528419 0.895 rs1277930 chr1:109822143 G/A cg00908766 chr1:109817496 CELSR2 0.45 4.62 0.38 9.36e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg04234412 chr22:24373322 LOC391322 -0.91 -10.67 -0.69 2.98e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3008870 0.917 rs12044492 chr1:67461667 T/C cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs2836974 0.526 rs1888488 chr21:40686521 C/T cg17971929 chr21:40555470 PSMG1 -0.69 -6.01 -0.47 1.95e-8 Cognitive function; TGCT cis rs17767294 0.614 rs116420641 chr6:28275458 G/A cg08851530 chr6:28072375 NA 1.54 6.89 0.53 2.51e-10 Parkinson's disease; TGCT cis rs8044995 0.501 rs7189887 chr16:68353915 C/T cg05110241 chr16:68378359 PRMT7 -0.37 -4.5 -0.37 1.55e-5 Schizophrenia; TGCT cis rs4925386 0.840 rs6143036 chr20:60921721 C/A cg06026331 chr20:60912101 LAMA5 0.36 5.74 0.46 6.75e-8 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs6684514 0.922 rs11264475 chr1:156306918 G/A cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7267979 1.000 rs6083813 chr20:25337671 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9911578 0.842 rs12450766 chr17:56832965 G/C cg05425664 chr17:57184151 TRIM37 0.61 5.45 0.44 2.62e-7 Intelligence (multi-trait analysis); TGCT cis rs1050631 0.924 rs1785918 chr18:33693198 C/T cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.98 0.41 2.07e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs11785400 0.762 rs7007349 chr8:143722673 T/C cg24634471 chr8:143751801 JRK 0.53 5.23 0.42 7.05e-7 Schizophrenia; TGCT cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs12477438 0.677 rs12475034 chr2:99699464 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.64 -5.05 -0.41 1.53e-6 Chronic sinus infection; TGCT cis rs6840360 0.571 rs4696110 chr4:152671325 G/A cg17479576 chr4:152424074 FAM160A1 -0.53 -5.29 -0.43 5.31e-7 Intelligence (multi-trait analysis); TGCT cis rs7528684 0.752 rs7546211 chr1:157741237 T/A cg17134153 chr1:157670328 FCRL3 -0.27 -4.86 -0.4 3.48e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs6121246 0.523 rs6060286 chr20:30197663 C/A cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs7829975 0.606 rs7837026 chr8:8801692 T/C cg00184457 chr8:8946301 NA -0.25 -4.53 -0.38 1.37e-5 Mood instability; TGCT cis rs9916302 0.861 rs593480 chr17:37453780 A/C cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT trans rs2727020 0.595 rs11040416 chr11:49566429 C/T cg15704280 chr7:45808275 SEPT13 -0.75 -8.8 -0.62 9.9e-15 Coronary artery disease; TGCT cis rs6089829 0.889 rs6122348 chr20:61663921 C/T cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7208859 0.673 rs11080135 chr17:29176481 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10504229 1.000 rs59708460 chr8:58196526 G/A cg08280861 chr8:58055591 NA 0.36 4.6 0.38 1.05e-5 Developmental language disorder (linguistic errors); TGCT cis rs2204008 0.840 rs11181795 chr12:38401129 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.39 0.55 1.92e-11 Bladder cancer; TGCT cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg19318889 chr4:1322082 MAEA 0.28 6.71 0.52 6.07e-10 Longevity; TGCT cis rs8180040 0.764 rs4683324 chr3:47251284 T/C cg27129171 chr3:47204927 SETD2 0.77 9.88 0.66 2.51e-17 Colorectal cancer; TGCT cis rs8072100 0.967 rs4239163 chr17:45755954 C/T cg08085267 chr17:45401833 C17orf57 -0.42 -4.6 -0.38 1.04e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2688608 0.592 rs3849967 chr10:75483366 C/T cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs7954584 0.583 rs6486782 chr12:122359172 T/C cg22168489 chr12:122356033 WDR66 0.23 5.55 0.45 1.63e-7 Mean corpuscular volume; TGCT cis rs240764 0.853 rs2001102 chr6:100978351 C/T cg21058520 chr6:100914733 NA 0.35 4.63 0.38 9.07e-6 Neuroticism; TGCT cis rs1784581 0.588 rs7765624 chr6:162427462 C/A cg17173639 chr6:162384350 PARK2 0.4 6.68 0.51 7.34e-10 Itch intensity from mosquito bite; TGCT cis rs7584330 0.518 rs80282956 chr2:238447929 G/A cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs6912958 0.712 rs2307379 chr6:88366771 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.55 -5.04 -0.41 1.58e-6 Monocyte percentage of white cells; TGCT cis rs9972944 0.702 rs987931 chr17:63765911 T/G cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs6570726 0.818 rs952405 chr6:145925952 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.59 0.38 1.07e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9649213 0.614 rs9641236 chr7:97998124 T/A cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.73 -0.62 1.45e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs10992471 0.627 rs10820980 chr9:95253342 C/T cg14631576 chr9:95140430 CENPP -0.31 -4.61 -0.38 9.95e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7666738 0.830 rs62321597 chr4:99014221 C/A cg18180107 chr4:99064573 C4orf37 0.56 5.28 0.43 5.54e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 0.727 rs283482 chr2:233646920 A/T cg25237894 chr2:233734115 C2orf82 0.27 5.01 0.41 1.86e-6 Coronary artery disease; TGCT cis rs78707713 0.560 rs12784882 chr10:71230334 C/G cg14388049 chr10:71211838 TSPAN15 -0.39 -4.64 -0.38 8.84e-6 Venous thromboembolism; TGCT cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.64 -0.45 1.08e-7 Coronary artery disease; TGCT cis rs10782582 0.593 rs6704444 chr1:76205108 T/C cg22875332 chr1:76189707 ACADM -0.5 -5.46 -0.44 2.48e-7 Daytime sleep phenotypes; TGCT cis rs9549260 0.564 rs9577107 chr13:41271676 A/T cg21288729 chr13:41239152 FOXO1 0.94 9.32 0.64 5.56e-16 Red blood cell count; TGCT cis rs751728 1.000 rs4711351 chr6:33754592 G/A cg00334056 chr6:33755658 LEMD2 -0.25 -4.52 -0.38 1.44e-5 Crohn's disease; TGCT cis rs73198271 0.595 rs117424193 chr8:8591377 T/C ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs13217239 0.646 rs12209886 chr6:26984757 G/A cg05738196 chr6:26577821 NA 0.49 4.77 0.39 4.98e-6 Schizophrenia; TGCT cis rs6138458 0.701 rs6138474 chr20:25012427 T/A cg26195577 chr20:24973756 C20orf3 0.99 9.24 0.64 8.46e-16 Blood protein levels; TGCT cis rs7044106 0.734 rs1981020 chr9:123388464 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.58 0.51 1.19e-9 Hip circumference adjusted for BMI; TGCT cis rs12477438 0.834 rs1563106 chr2:99701381 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.69 -6.1 -0.48 1.28e-8 Chronic sinus infection; TGCT cis rs13108904 0.560 rs11247994 chr4:1343720 G/A cg03303774 chr4:1407052 NA 0.38 5.88 0.47 3.49e-8 Obesity-related traits; TGCT cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs10510102 0.872 rs28586586 chr10:123709743 T/C cg23691251 chr10:123688108 ATE1 -0.58 -4.67 -0.39 7.77e-6 Breast cancer; TGCT cis rs7772486 0.875 rs854146 chr6:146341033 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.86 0.66 2.8e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs7937612 1.000 rs11217841 chr11:120238721 C/A cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.7 -0.39 6.76e-6 Intraocular pressure; TGCT cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg04287289 chr16:89883240 FANCA 0.72 7.39 0.55 1.87e-11 Vitiligo; TGCT cis rs739496 0.615 rs3809274 chr12:112044333 G/C cg10833066 chr12:111807467 FAM109A 0.36 4.98 0.41 2.1e-6 Platelet count; TGCT cis rs2439831 0.850 rs2957637 chr15:43951118 C/A cg19166733 chr15:44192098 FRMD5 -0.25 -4.74 -0.39 5.85e-6 Lung cancer in ever smokers; TGCT cis rs17767294 0.708 rs72848784 chr6:27970783 A/G cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs35306767 0.903 rs35370435 chr10:898205 T/C cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs7975161 0.572 rs10861163 chr12:104568613 C/A cg25273343 chr12:104657179 TXNRD1 -0.32 -4.45 -0.37 1.88e-5 Toenail selenium levels; TGCT cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg09436375 chr6:42928200 GNMT -0.36 -4.46 -0.37 1.78e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10791097 0.694 rs1054869 chr11:130742630 G/A cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7909074 0.766 rs5000415 chr10:45383674 C/T cg04218760 chr10:45406644 TMEM72 -0.29 -5.63 -0.45 1.15e-7 Mean corpuscular volume; TGCT cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3772130 1.000 rs11714406 chr3:121372513 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.55 5.02 0.41 1.77e-6 Cognitive performance; TGCT cis rs3008870 0.755 rs2755242 chr1:67479598 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.81 8.4 0.6 8.51e-14 Lymphocyte percentage of white cells; TGCT trans rs34421088 0.559 rs12386974 chr8:11400628 C/G cg06636001 chr8:8085503 FLJ10661 0.72 6.87 0.53 2.81e-10 Neuroticism; TGCT cis rs7617480 0.549 rs9879978 chr3:48846600 T/G cg07636037 chr3:49044803 WDR6 0.78 6.5 0.5 1.73e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7552404 1.000 rs1498316 chr1:76159198 G/A cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7647973 1.000 rs73088137 chr3:49448423 G/A cg06212747 chr3:49208901 KLHDC8B -0.59 -4.68 -0.39 7.32e-6 Menarche (age at onset); TGCT cis rs2243480 1.000 rs2707831 chr7:66062511 G/A cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs35146811 0.735 rs6465766 chr7:99785671 A/G cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs826838 0.651 rs1843892 chr12:38616965 A/G cg26384229 chr12:38710491 ALG10B 0.65 6.07 0.48 1.44e-8 Heart rate; TGCT cis rs12497850 0.805 rs11130176 chr3:48844077 A/G cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs422249 0.547 rs174536 chr11:61551927 A/C cg19610905 chr11:61596333 FADS2 -1.04 -10.72 -0.69 2.19e-19 Trans fatty acid levels; TGCT cis rs614226 0.516 rs1794748 chr12:120953758 A/G cg10072921 chr12:121022843 NA -0.44 -4.74 -0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs60871478 0.579 rs56109762 chr7:925967 G/A cg15782153 chr7:917662 C7orf20 0.58 5.19 0.42 8.5e-7 Cerebrospinal P-tau181p levels; TGCT cis rs112591243 0.685 rs2839338 chr21:47987984 C/T cg10657630 chr21:48055338 PRMT2 0.96 5.11 0.42 1.17e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs3784262 0.564 rs34958088 chr15:58328332 G/C cg12031962 chr15:58353849 ALDH1A2 -0.45 -6.67 -0.51 7.61e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6088580 0.634 rs945673 chr20:32964265 C/A cg06115741 chr20:33292138 TP53INP2 -0.54 -4.64 -0.38 8.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs6088580 0.634 rs2424992 chr20:33012060 C/T cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs826838 0.967 rs1486345 chr12:39131677 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs11252926 0.537 rs4881255 chr10:453638 T/C cg13477178 chr10:375248 DIP2C -0.25 -4.72 -0.39 6.33e-6 Psychosis in Alzheimer's disease; TGCT cis rs57590327 0.612 rs820272 chr3:81554345 T/C cg07356753 chr3:81810745 GBE1 0.54 4.44 0.37 1.98e-5 Extraversion; TGCT cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs4803468 1.000 rs2241710 chr19:41912092 G/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.69 -0.69 2.72e-19 Height; TGCT cis rs79149102 0.579 rs9788648 chr15:75300284 A/G cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs7666738 0.715 rs61114099 chr4:98931270 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.586 rs6050432 chr20:25184028 T/C cg16686733 chr20:25566563 NINL 0.53 5.43 0.44 2.9e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9818758 0.607 rs34784192 chr3:49274823 G/T cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs28595532 0.841 rs114107504 chr4:119771080 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs7552404 0.731 rs1770885 chr1:76402212 C/T cg22875332 chr1:76189707 ACADM -0.67 -6.89 -0.53 2.5e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4654899 1.000 rs7522722 chr1:21481840 G/A cg01072550 chr1:21505969 NA -0.5 -8.08 -0.59 4.94e-13 Superior frontal gyrus grey matter volume; TGCT cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg06636001 chr8:8085503 FLJ10661 -0.64 -5.78 -0.46 5.7e-8 Mood instability; TGCT cis rs78487399 0.908 rs6712944 chr2:43834118 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2227564 0.620 rs4746143 chr10:75477298 A/G cg04320760 chr10:75533139 FUT11 -0.32 -4.5 -0.37 1.56e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6121246 0.567 rs6060261 chr20:30192948 C/G cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs13242816 1.000 rs2191499 chr7:116138599 C/T cg02799643 chr7:116139180 CAV2 -0.45 -5.85 -0.47 4.03e-8 P wave duration; TGCT cis rs1008375 1.000 rs28480159 chr4:17685707 A/C cg18681998 chr4:17616180 MED28 0.92 10.51 0.69 7.15e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2239547 0.618 rs13083728 chr3:52868445 G/A cg11645453 chr3:52864694 ITIH4 0.35 5.75 0.46 6.41e-8 Schizophrenia; TGCT cis rs6430585 0.528 rs12474975 chr2:136702118 A/T cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs10992471 0.729 rs7042335 chr9:95122547 C/T cg14631576 chr9:95140430 CENPP -0.3 -4.85 -0.4 3.62e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2456568 0.867 rs2511375 chr11:93671117 T/G cg26875233 chr11:93583750 C11orf90 -0.45 -5.61 -0.45 1.28e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9911578 0.935 rs7218105 chr17:57041119 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs16867321 0.527 rs7571457 chr2:181590172 C/T cg12875548 chr2:181044332 NA -0.36 -4.7 -0.39 6.68e-6 Obesity; TGCT cis rs6988636 1.000 rs6988636 chr8:124185970 A/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs687432 0.774 rs7945154 chr11:57912638 G/A cg04811534 chr11:57115016 P2RX3 0.18 4.48 0.37 1.68e-5 Parkinson's disease; TGCT cis rs3857536 0.566 rs208463 chr6:66913962 T/A cg07460842 chr6:66804631 NA -0.68 -6.73 -0.52 5.5e-10 Blood trace element (Cu levels); TGCT cis rs7662987 0.517 rs4235436 chr4:100039620 G/A cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs981844 0.645 rs72731677 chr4:154671475 C/G cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs9916302 0.904 rs35335692 chr17:37710006 A/G cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs6542838 0.609 rs13028500 chr2:99528296 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.16 -0.42 9.49e-7 Fear of minor pain; TGCT cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.84 0.4 3.86e-6 Platelet count; TGCT cis rs9303401 0.614 rs17175663 chr17:57108437 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.8 0.46 5.11e-8 Cognitive test performance; TGCT cis rs11874712 1.000 rs1800637 chr18:43670190 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs854765 0.647 rs854770 chr17:18019048 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.71 7.37 0.55 2.15e-11 Total body bone mineral density; TGCT cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg03264133 chr6:25882463 NA 0.52 5.51 0.44 2.01e-7 Blood metabolite levels; TGCT cis rs9419702 0.568 rs7920966 chr10:133555185 G/T cg04492858 chr10:133558786 NA 0.53 5.74 0.46 6.88e-8 Survival in rectal cancer; TGCT cis rs7267979 1.000 rs6050598 chr20:25397257 C/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2013441 0.932 rs3850785 chr17:20185248 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs9581857 0.615 rs79553479 chr13:28007862 G/A cg22138327 chr13:27999177 GTF3A 0.78 5.26 0.43 5.98e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs11098499 0.908 rs1002152 chr4:120273387 C/A cg09307838 chr4:120376055 NA 0.63 6.17 0.48 8.9e-9 Corneal astigmatism; TGCT cis rs7267979 1.000 rs7018 chr20:25278261 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6121246 0.567 rs6120937 chr20:30219721 C/T cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg08280861 chr8:58055591 NA 0.38 4.7 0.39 6.87e-6 Developmental language disorder (linguistic errors); TGCT cis rs4689592 0.503 rs66885632 chr4:7053738 T/C cg25660036 chr4:7070649 GRPEL1 0.58 4.46 0.37 1.8e-5 Monocyte percentage of white cells; TGCT cis rs6912958 0.582 rs242285 chr6:88070743 G/A cg10393598 chr6:87862264 NA -0.31 -4.45 -0.37 1.86e-5 Monocyte percentage of white cells; TGCT cis rs73198271 0.740 rs1039912 chr8:8648229 C/T cg06636001 chr8:8085503 FLJ10661 -0.6 -4.65 -0.39 8.23e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs919433 0.617 rs4850807 chr2:198575975 G/A cg00792783 chr2:198669748 PLCL1 -0.55 -5.04 -0.41 1.62e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg13683864 chr3:40499215 RPL14 1.14 12.22 0.74 4.89e-23 Renal cell carcinoma; TGCT cis rs8014252 0.803 rs73282126 chr14:70986041 T/C cg11204974 chr14:71022665 NA -0.53 -4.46 -0.37 1.79e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs478304 0.654 rs6591185 chr11:65455742 A/G cg27068330 chr11:65405492 SIPA1 -0.99 -11.36 -0.71 6.13e-21 Acne (severe); TGCT cis rs4665809 1.000 rs750451 chr2:26324241 G/A cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs1552244 1.000 rs6791810 chr3:10124444 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.49 6.64 0.51 8.8e-10 Alzheimer's disease; TGCT cis rs6952808 0.730 rs55948146 chr7:1866953 G/C cg22963979 chr7:1858916 MAD1L1 0.32 5.02 0.41 1.73e-6 Bipolar disorder and schizophrenia; TGCT cis rs1401999 1.000 rs7620350 chr3:183710053 A/T cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs9486719 1.000 rs28623445 chr6:96899116 G/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs2334880 0.713 rs4788828 chr16:71724090 C/A cg06353428 chr16:71660113 MARVELD3 1.56 12.9 0.76 1.15e-24 Malaria; TGCT cis rs727563 0.594 rs5758408 chr22:42077737 A/C cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7119038 0.865 rs11217044 chr11:118696022 T/C cg19308663 chr11:118741387 NA 0.27 5.62 0.45 1.22e-7 Sjögren's syndrome; TGCT cis rs4654899 1.000 rs12133780 chr1:21270808 G/A cg01072550 chr1:21505969 NA -0.48 -7.63 -0.57 5.3e-12 Superior frontal gyrus grey matter volume; TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg27535305 chr1:53392650 SCP2 -0.29 -5.59 -0.45 1.4e-7 Monocyte count; TGCT trans rs2970818 0.831 rs7304949 chr12:4609625 A/G cg22985033 chr20:36975012 LBP 0.24 7.21 0.54 4.77e-11 Phosphorus levels; TGCT cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs9522267 0.502 rs9522297 chr13:112234419 C/T cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs72717009 0.825 rs12722986 chr1:161465420 A/G cg23840854 chr1:161414152 NA -1.05 -6.11 -0.48 1.18e-8 Rheumatoid arthritis; TGCT cis rs6121246 0.583 rs28815498 chr20:30351560 T/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT trans rs916888 0.610 rs199444 chr17:44818276 T/C cg10053473 chr17:62856997 LRRC37A3 -0.41 -6.8 -0.52 3.85e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg10802521 chr3:52805072 NEK4 -0.7 -8.75 -0.62 1.28e-14 Bipolar disorder; TGCT cis rs854765 0.647 rs9303144 chr17:17977355 T/C cg00306284 chr17:18855313 SLC5A10 0.23 4.43 0.37 2.01e-5 Total body bone mineral density; TGCT cis rs1862618 0.641 rs2591954 chr5:56245044 G/C cg12311346 chr5:56204834 C5orf35 0.57 6.09 0.48 1.28e-8 Initial pursuit acceleration; TGCT cis rs4268898 0.735 rs34125395 chr2:24558242 C/T cg02683114 chr2:24398427 C2orf84 0.2 4.92 0.4 2.65e-6 Asthma; TGCT cis rs308403 0.608 rs309368 chr4:123662997 A/T cg10495464 chr4:123653540 BBS12;LOC729338 0.71 6.35 0.5 3.79e-9 Blood protein levels; TGCT cis rs9640161 0.636 rs3735171 chr7:150033882 A/G cg10018233 chr7:150070692 REPIN1 0.31 4.6 0.38 1.03e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs9993613 0.808 rs1518492 chr4:73433875 G/A cg15102770 chr4:73434591 ADAMTS3 -0.5 -4.59 -0.38 1.09e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs7412746 0.611 rs2256355 chr1:150811794 A/G cg09365446 chr1:150670422 GOLPH3L 0.32 4.61 0.38 9.85e-6 Melanoma; TGCT trans rs3780486 0.522 rs1328898 chr9:33163271 A/G cg20290983 chr6:43655470 MRPS18A 0.77 8.36 0.6 1.07e-13 IgG glycosylation; TGCT cis rs7666738 0.830 rs13116691 chr4:98929771 A/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2639990 1.000 rs1702831 chr18:72897368 C/A cg18449964 chr18:72917101 ZADH2 0.91 6.22 0.49 7e-9 Vascular endothelial growth factor levels; TGCT cis rs904251 0.600 rs2270687 chr6:37418263 A/G cg01843034 chr6:37503916 NA -0.48 -6.05 -0.48 1.6e-8 Cognitive performance; TGCT cis rs10876993 0.728 rs1082503 chr12:58036717 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.78 -0.46 5.57e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs6433895 1.000 rs55954384 chr2:182017630 A/G cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg27535305 chr1:53392650 SCP2 0.27 5.33 0.43 4.5e-7 Monocyte count; TGCT cis rs6121246 0.909 rs6060812 chr20:30292803 C/T cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs3020736 0.500 rs6002623 chr22:42513761 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2469997 1.000 rs2470003 chr8:120357482 C/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.584 rs11205997 chr1:53195271 G/C cg08859206 chr1:53392774 SCP2 0.34 4.82 0.4 4.1e-6 Monocyte count; TGCT cis rs3812049 0.693 rs9327468 chr5:127441861 C/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.64 5.87 0.47 3.81e-8 Lymphocyte counts;Red cell distribution width; TGCT cis rs709400 0.633 rs10135868 chr14:104004147 T/C cg12935359 chr14:103987150 CKB -0.38 -5.67 -0.45 9.37e-8 Body mass index; TGCT cis rs2842992 0.830 rs1853259 chr6:160147441 A/G cg11366901 chr6:160182831 ACAT2 -1.02 -6.82 -0.52 3.57e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs9611565 0.625 rs12483991 chr22:41935285 A/G cg03806693 chr22:41940476 POLR3H -1.01 -11.32 -0.71 7.68e-21 Vitiligo; TGCT cis rs7267979 1.000 rs422844 chr20:25445591 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3784262 0.669 rs7180059 chr15:58288172 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.96 -0.47 2.49e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg10047753 chr17:41438598 NA 0.99 10.22 0.68 3.71e-18 Menopause (age at onset); TGCT cis rs514406 0.505 rs437954 chr1:53173321 C/G cg01802117 chr1:53393560 SCP2 -0.4 -4.66 -0.39 8.05e-6 Monocyte count; TGCT cis rs861020 0.630 rs592694 chr1:210009533 G/T cg05527609 chr1:210001259 C1orf107 0.89 8.36 0.6 1.08e-13 Orofacial clefts; TGCT cis rs11792861 0.781 rs2151426 chr9:111743797 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.53 0.38 1.37e-5 Menarche (age at onset); TGCT cis rs2982552 0.708 rs1609624 chr6:152081009 T/C cg22157087 chr6:152012887 ESR1 0.19 4.57 0.38 1.17e-5 Bone properties (heel); TGCT cis rs1008375 0.863 rs7680984 chr4:17600884 A/G cg18681998 chr4:17616180 MED28 1.05 10.51 0.69 7.43e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12210905 1.000 rs12189835 chr6:27198271 T/C cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT trans rs3780486 0.522 rs7029897 chr9:33124042 T/C cg04842962 chr6:43655489 MRPS18A 0.83 9.02 0.63 2.9e-15 IgG glycosylation; TGCT cis rs9682041 1.000 rs6444920 chr3:170090374 A/G cg11886554 chr3:170076028 SKIL 0.83 6.42 0.5 2.66e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs4665809 1.000 rs4233710 chr2:26291565 G/A cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT trans rs629535 0.862 rs654604 chr8:70048939 C/A cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs40363 1.000 rs1635393 chr16:3520493 C/T cg00484396 chr16:3507460 NAT15 0.42 5.05 0.41 1.51e-6 Tuberculosis; TGCT cis rs11122272 0.735 rs2749706 chr1:231527170 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.32 -0.49 4.24e-9 Hemoglobin concentration; TGCT cis rs6121246 0.865 rs77130187 chr20:30269060 G/A cg13852791 chr20:30311386 BCL2L1 0.68 4.79 0.4 4.6e-6 Mean corpuscular hemoglobin; TGCT cis rs2115630 0.967 rs8027779 chr15:85255385 T/C cg17173187 chr15:85201210 NMB -0.4 -5.02 -0.41 1.78e-6 P wave terminal force; TGCT cis rs57590327 0.504 rs4856349 chr3:81502928 C/T cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs763014 1.000 rs7205409 chr16:642610 A/G cg00908189 chr16:619842 PIGQ 0.8 8.92 0.63 5.12e-15 Height; TGCT cis rs2688608 0.836 rs2675668 chr10:75636148 G/A cg19442545 chr10:75533431 FUT11 -0.31 -4.97 -0.41 2.13e-6 Inflammatory bowel disease; TGCT cis rs752092 0.894 rs8042989 chr15:101770761 T/A cg25114630 chr15:101792522 CHSY1 0.5 4.7 0.39 6.7e-6 Corneal structure; TGCT cis rs17030434 0.654 rs10021631 chr4:154646675 A/G cg14289246 chr4:154710475 SFRP2 -0.79 -5.87 -0.47 3.7e-8 Electrocardiographic conduction measures; TGCT cis rs2456568 0.531 rs7105060 chr11:93661268 C/A cg26875233 chr11:93583750 C11orf90 -0.41 -4.94 -0.41 2.43e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1371867 0.764 rs1020171 chr8:101288610 T/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.5 -0.37 1.53e-5 Atrioventricular conduction; TGCT cis rs67073037 0.955 rs11689719 chr2:29122001 G/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs6752107 1.000 rs6752107 chr2:234161448 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.65 0.39 8.38e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2354432 0.607 rs1530335 chr1:146685288 T/C cg25205988 chr1:146714368 CHD1L 1.34 6.23 0.49 6.59e-9 Mitochondrial DNA levels; TGCT cis rs7944584 0.588 rs11988 chr11:47261260 G/A cg20307385 chr11:47447363 PSMC3 0.79 7.75 0.57 2.86e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs79349575 0.745 rs170319 chr17:46991531 T/C cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs12367572 1.000 rs12367572 chr12:45290466 C/T cg04608330 chr12:45269318 NELL2 0.66 6.82 0.52 3.59e-10 Gut microbiome composition (summer); TGCT cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg06238570 chr21:40685208 BRWD1 0.67 6.18 0.49 8.49e-9 Cognitive function; TGCT cis rs9894429 0.683 rs112612275 chr17:79552604 C/A cg18240062 chr17:79603768 NPLOC4 -0.85 -10.0 -0.67 1.28e-17 Eye color traits; TGCT cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs6815814 0.904 rs67712706 chr4:38820616 A/G cg02016764 chr4:38805732 TLR1 -0.34 -5.35 -0.43 4.05e-7 Breast cancer; TGCT cis rs589448 0.538 rs622656 chr12:69753595 C/T cg20891283 chr12:69753455 YEATS4 0.67 5.91 0.47 3.11e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9517313 0.551 rs2274051 chr13:99091634 A/G cg07423050 chr13:99094983 FARP1 0.29 5.42 0.44 3.04e-7 Neuroticism; TGCT cis rs9811920 0.609 rs17174947 chr3:99598884 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.58 -6.55 -0.51 1.35e-9 Axial length; TGCT cis rs1670533 1.000 rs10084890 chr4:1053934 C/G cg20887711 chr4:1340912 KIAA1530 -0.63 -4.93 -0.4 2.58e-6 Recombination rate (females); TGCT cis rs344364 0.511 rs1657133 chr16:1950300 A/G cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9486719 1.000 rs11153018 chr6:96956137 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs4595586 0.545 rs1400284 chr12:39400419 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs265548 0.646 rs36689 chr19:17910639 A/G cg03316864 chr19:17906309 B3GNT3 0.47 5.67 0.45 9.52e-8 Tumor biomarkers; TGCT cis rs2197308 0.765 rs11182964 chr12:37935052 C/T cg26384229 chr12:38710491 ALG10B 0.87 7.83 0.58 1.85e-12 Morning vs. evening chronotype; TGCT cis rs9916302 0.904 rs4795356 chr17:37535631 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs2016266 0.750 rs10876432 chr12:53731891 G/A cg16917193 chr12:54089295 NA 0.68 4.55 0.38 1.24e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs7267979 0.933 rs1130694 chr20:25276297 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs317689 0.918 rs581911 chr12:69738293 C/T cg11871910 chr12:69753446 YEATS4 0.57 4.88 0.4 3.13e-6 Response to diuretic therapy; TGCT trans rs797680 0.856 rs7541687 chr1:93656588 A/G cg27528825 chr2:159282178 CCDC148 -0.35 -6.82 -0.52 3.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs950169 0.580 rs11630887 chr15:85193015 A/T cg12863693 chr15:85201151 NMB 0.45 5.38 0.44 3.55e-7 Schizophrenia; TGCT cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.61 -0.51 1e-9 Alzheimer's disease; TGCT trans rs561341 0.883 rs2074102 chr17:30228884 G/A cg20587970 chr11:113659929 NA -0.82 -9.73 -0.66 5.87e-17 Hip circumference adjusted for BMI; TGCT cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg12310025 chr6:25882481 NA 0.9 8.89 0.62 5.87e-15 Blood metabolite levels; TGCT cis rs8014204 0.935 rs3742786 chr14:75373011 A/G cg06637938 chr14:75390232 RPS6KL1 -0.71 -6.87 -0.53 2.75e-10 Caffeine consumption; TGCT cis rs1153858 1.000 rs12437840 chr15:45669055 C/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg23758822 chr17:41437982 NA -0.7 -6.61 -0.51 1.05e-9 Menopause (age at onset); TGCT cis rs7613051 0.945 rs7629880 chr3:33058811 C/T cg19000631 chr3:33138515 GLB1;TMPPE -0.64 -4.74 -0.39 5.79e-6 Atopic dermatitis; TGCT cis rs4285028 0.948 rs34696871 chr3:121671880 T/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.79 -6.68 -0.51 7.11e-10 Multiple sclerosis; TGCT cis rs832540 0.931 rs832536 chr5:56212595 C/T cg12311346 chr5:56204834 C5orf35 -0.47 -4.97 -0.41 2.15e-6 Coronary artery disease; TGCT cis rs10791323 0.572 rs10750551 chr11:133737462 G/A cg03690763 chr11:133734501 NA -0.28 -4.79 -0.39 4.75e-6 Childhood ear infection; TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg08736216 chr1:53307985 ZYG11A -0.27 -5.41 -0.44 3.12e-7 Monocyte count; TGCT cis rs9796 0.558 rs7166205 chr15:41514733 A/G cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.18 -0.54 5.56e-11 Menopause (age at onset); TGCT cis rs3008870 0.883 rs2755249 chr1:67493662 A/G cg11518657 chr1:67396239 MIER1 0.52 4.47 0.37 1.73e-5 Lymphocyte percentage of white cells; TGCT cis rs478304 0.654 rs7934036 chr11:65451020 G/T cg27068330 chr11:65405492 SIPA1 -1.01 -11.16 -0.71 1.94e-20 Acne (severe); TGCT cis rs8017423 1.000 rs10129210 chr14:90668379 G/T cg04374321 chr14:90722782 PSMC1 0.77 7.95 0.58 9.78e-13 Mortality in heart failure; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg21226059 chr5:178986404 RUFY1 -0.62 -7.28 -0.55 3.37e-11 Lung cancer; TGCT cis rs4273100 0.607 rs8072587 chr17:19211073 C/G cg03910582 chr17:19030146 GRAPL -0.51 -6.2 -0.49 7.86e-9 Schizophrenia; TGCT trans rs1814175 0.935 rs6485999 chr11:49658986 G/C cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs514406 0.584 rs11205997 chr1:53195271 G/C cg24675658 chr1:53192096 ZYG11B 0.84 10.45 0.68 1.03e-18 Monocyte count; TGCT cis rs12477438 0.871 rs62156364 chr2:99695097 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.6 -4.71 -0.39 6.43e-6 Chronic sinus infection; TGCT cis rs7267979 1.000 rs4815421 chr20:25386509 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7829975 0.572 rs28730413 chr8:8795447 A/C cg15556689 chr8:8085844 FLJ10661 -0.67 -6.12 -0.48 1.14e-8 Mood instability; TGCT cis rs28374715 0.635 rs8023530 chr15:41647775 T/C cg18705301 chr15:41695430 NDUFAF1 -0.85 -13.66 -0.78 1.71e-26 Ulcerative colitis; TGCT cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg05368731 chr17:41323189 NBR1 1.16 13.48 0.77 4.59e-26 Menopause (age at onset); TGCT cis rs7726839 0.507 rs60068988 chr5:597668 T/C cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs35306767 0.761 rs11253538 chr10:1011166 C/T cg18964960 chr10:1102726 WDR37 0.69 4.82 0.4 4.12e-6 Eosinophil percentage of granulocytes; TGCT cis rs58688157 0.960 rs1131665 chr11:613208 T/C cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs4805272 0.512 rs11879141 chr19:29320335 G/A cg03161606 chr19:29218774 NA 0.54 4.48 0.37 1.68e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs6665290 0.904 rs6690803 chr1:227189106 C/T cg10327440 chr1:227177885 CDC42BPA -0.98 -20.01 -0.87 1.24e-40 Myeloid white cell count; TGCT cis rs6671200 1.000 rs71654417 chr1:95661200 G/A cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs853679 0.517 rs9348793 chr6:28084189 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs8037137 0.915 rs12594752 chr15:91531995 C/T cg22570213 chr15:91497863 RCCD1 0.5 4.65 0.39 8.27e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs1218582 0.772 rs2102423 chr1:154916068 A/G cg09359103 chr1:154839909 KCNN3 -0.63 -11.36 -0.71 6.16e-21 Prostate cancer; TGCT cis rs7829975 0.682 rs7013471 chr8:8687325 A/G cg06636001 chr8:8085503 FLJ10661 -0.74 -6.68 -0.51 7.15e-10 Mood instability; TGCT cis rs5769765 0.955 rs2319465 chr22:50265784 A/C cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg08219700 chr8:58056026 NA 0.3 4.55 0.38 1.25e-5 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs17323034 chr4:119606518 G/A cg11846333 chr4:119757529 SEC24D 0.92 5.01 0.41 1.85e-6 Cannabis dependence symptom count; TGCT cis rs6866344 0.697 rs17184302 chr5:178127676 C/T cg10224037 chr5:178157518 ZNF354A 0.93 7.9 0.58 1.26e-12 Neutrophil percentage of white cells; TGCT cis rs11679640 1.000 rs11679640 chr2:43141485 C/G cg18281102 chr2:44065550 ABCG5;ABCG8 -0.27 -4.56 -0.38 1.22e-5 White matter hyperintensity burden; TGCT cis rs2760061 0.583 rs708123 chr1:228220495 A/G cg18477163 chr1:228402036 OBSCN 0.35 7.05 0.53 1.11e-10 Diastolic blood pressure; TGCT cis rs881375 0.967 rs1930778 chr9:123641369 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.4 4.64 0.38 8.85e-6 Rheumatoid arthritis; TGCT cis rs34467563 0.967 rs62516311 chr8:97400975 G/A cg15747595 chr8:98289880 TSPYL5 -0.41 -4.44 -0.37 1.99e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9883204 0.817 rs17361324 chr3:123131254 C/T cg04890266 chr3:123102914 ADCY5 0.33 4.79 0.4 4.68e-6 Birth weight; TGCT cis rs1008375 0.686 rs34338142 chr4:17626174 T/A cg16339924 chr4:17578868 LAP3 0.72 5.67 0.45 9.56e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3820068 0.603 rs10492986 chr1:15988702 T/C cg05660106 chr1:15850417 CASP9 0.81 7.67 0.57 4.28e-12 Systolic blood pressure; TGCT cis rs6665290 0.901 rs61834005 chr1:227202789 C/T cg11404489 chr1:228071452 NA -0.19 -4.61 -0.38 9.97e-6 Myeloid white cell count; TGCT cis rs7666738 0.830 rs1456208 chr4:98678563 C/T cg05340658 chr4:99064831 C4orf37 0.46 5.42 0.44 3.01e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9814567 1.000 rs11708531 chr3:134224902 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs80282103 0.618 rs74117850 chr10:1165777 T/C cg18964960 chr10:1102726 WDR37 1.03 4.53 0.38 1.39e-5 Glomerular filtration rate (creatinine); TGCT cis rs60154123 0.505 rs1319435 chr1:210047618 C/T cg23283495 chr1:209979779 IRF6 -0.63 -4.6 -0.38 1.04e-5 Coronary artery disease; TGCT cis rs7786808 0.653 rs4909213 chr7:158202404 G/A cg01191920 chr7:158217561 PTPRN2 -0.44 -6.59 -0.51 1.11e-9 Obesity-related traits; TGCT cis rs34014631 1.000 rs75823291 chr10:103567057 A/C cg22630918 chr10:102748988 C10orf2 0.43 4.8 0.4 4.57e-6 Coronary artery calcification; TGCT cis rs6543140 0.964 rs7561351 chr2:103077780 A/G cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg02725872 chr8:58115012 NA -0.37 -4.99 -0.41 1.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.520 rs4402818 chr2:99717608 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 12.68 0.75 3.78e-24 Chronic sinus infection; TGCT cis rs6558530 0.625 rs7459507 chr8:1698192 A/G cg09410841 chr8:1729607 CLN8 0.71 6.23 0.49 6.68e-9 Systolic blood pressure; TGCT cis rs9611565 0.921 rs5758297 chr22:41720697 A/G cg03806693 chr22:41940476 POLR3H -0.86 -9.19 -0.64 1.16e-15 Vitiligo; TGCT cis rs2354432 0.556 rs6593777 chr1:146884013 C/G cg25205988 chr1:146714368 CHD1L 1.32 5.88 0.47 3.62e-8 Mitochondrial DNA levels; TGCT cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs9733 0.569 rs11204691 chr1:150644339 A/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs2153535 0.580 rs1414346 chr6:8471574 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2932538 0.922 rs12401734 chr1:113071834 A/G cg22162597 chr1:113214053 CAPZA1 0.26 5.65 0.45 1.06e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs4654899 0.680 rs6692553 chr1:21221497 C/T cg01072550 chr1:21505969 NA 0.54 8.66 0.61 2.06e-14 Superior frontal gyrus grey matter volume; TGCT cis rs854765 0.624 rs11652144 chr17:17733934 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.66 -0.51 7.85e-10 Total body bone mineral density; TGCT cis rs1982963 1.000 rs904061 chr14:52504624 T/C cg10843707 chr14:52510701 NID2 -0.43 -6.6 -0.51 1.09e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.830 rs4699591 chr4:98974171 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3087591 0.683 rs17826544 chr17:29640225 A/G cg24425628 chr17:29625626 OMG;NF1 0.39 5.74 0.46 6.74e-8 Hip circumference; TGCT cis rs7267979 1.000 rs4815420 chr20:25383979 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6940638 0.956 rs36048693 chr6:27032711 T/G cg26531700 chr6:26746687 NA -0.62 -4.71 -0.39 6.59e-6 Intelligence (multi-trait analysis); TGCT trans rs797680 0.964 rs547866 chr1:93725053 C/T cg27528825 chr2:159282178 CCDC148 0.34 6.65 0.51 8.23e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs245880 0.740 rs245892 chr7:29191273 T/C cg17163760 chr7:29186267 CPVL -0.41 -5.21 -0.42 7.51e-7 Warfarin maintenance dose; TGCT cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs7646881 0.504 rs67305172 chr3:158464274 A/G cg18349298 chr3:158450550 RARRES1 0.42 4.44 0.37 1.97e-5 Tetralogy of Fallot; TGCT cis rs826838 0.967 rs34496261 chr12:39023829 G/A cg26384229 chr12:38710491 ALG10B 1.02 9.78 0.66 4.37e-17 Heart rate; TGCT cis rs6582630 0.537 rs1949610 chr12:38387838 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.72e-11 Drug-induced liver injury (flucloxacillin); TGCT trans rs804280 0.518 rs34266352 chr8:11791462 G/A cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Myopia (pathological); TGCT cis rs67311347 0.956 rs12633446 chr3:40505661 G/A cg13683864 chr3:40499215 RPL14 1.04 10.6 0.69 4.48e-19 Renal cell carcinoma; TGCT cis rs3824867 1.000 rs3824867 chr11:47468569 A/G cg20307385 chr11:47447363 PSMC3 0.69 5.93 0.47 2.74e-8 Mean corpuscular hemoglobin; TGCT trans rs7618501 0.521 rs3733134 chr3:49939503 C/T cg21659725 chr3:3221576 CRBN 0.72 8.23 0.59 2.18e-13 Intelligence (multi-trait analysis); TGCT cis rs9393692 1.000 rs3999544 chr6:26285867 C/T cg05868516 chr6:26286170 HIST1H4H 0.62 5.75 0.46 6.64e-8 Educational attainment; TGCT cis rs7552404 1.000 rs11161515 chr1:76212559 C/T cg10523679 chr1:76189770 ACADM 0.89 9.53 0.65 1.72e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg09904177 chr6:26538194 HMGN4 0.64 5.95 0.47 2.56e-8 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.616 rs10839388 chr11:49842603 C/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs7017914 0.967 rs2933853 chr8:71909222 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.59 -5.51 -0.44 1.97e-7 Bone mineral density; TGCT cis rs593531 0.571 rs10793081 chr11:74092403 T/C cg25592907 chr11:73676012 DNAJB13 0.31 4.52 0.38 1.45e-5 Neuroticism; TGCT cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs7659604 0.846 rs35986491 chr4:122664528 A/T cg19748678 chr4:122722346 EXOSC9 0.57 5.54 0.45 1.69e-7 Type 2 diabetes; TGCT cis rs9926296 0.546 rs7187436 chr16:89845110 A/T cg26513180 chr16:89883248 FANCA 1.05 13.97 0.78 3.22e-27 Vitiligo; TGCT cis rs60871478 0.786 rs55899111 chr7:827843 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.48 -4.56 -0.38 1.22e-5 Cerebrospinal P-tau181p levels; TGCT cis rs7940866 0.874 rs1433979 chr11:130871617 G/A cg12179176 chr11:130786555 SNX19 0.47 4.56 0.38 1.22e-5 Schizophrenia; TGCT cis rs60843830 1.000 rs3791220 chr2:227066 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.94 0.53 1.91e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg10295955 chr4:187884368 NA -1.0 -14.26 -0.79 6.69e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.966 rs3827014 chr20:25371559 C/T cg03522245 chr20:25566470 NINL -0.63 -6.71 -0.52 6.13e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2235642 0.821 rs2281234 chr16:1602938 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -5.06 -0.41 1.46e-6 Coronary artery disease; TGCT cis rs6032067 0.636 rs6104092 chr20:43906730 A/G cg16667508 chr20:43936853 MATN4;RBPJL 0.44 6.99 0.53 1.48e-10 Blood protein levels; TGCT cis rs12477438 0.520 rs720229 chr2:99704273 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.33 0.79 4.57e-28 Chronic sinus infection; TGCT cis rs3812831 0.643 rs7322339 chr13:114929726 C/A cg06611532 chr13:114900021 NA 0.37 6.85 0.52 3.08e-10 Schizophrenia; TGCT cis rs3026101 0.599 rs1058381 chr17:5288018 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.63 0.38 9.15e-6 Body mass index; TGCT cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs7044106 0.791 rs10818473 chr9:123484155 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 6.92 0.53 2.14e-10 Hip circumference adjusted for BMI; TGCT cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs2204008 0.628 rs10876106 chr12:37990767 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.56e-12 Bladder cancer; TGCT cis rs9394841 0.667 rs1891453 chr6:41765265 T/C cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg24846343 chr22:24311635 DDTL -0.21 -4.74 -0.39 5.69e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467773 1.000 rs9467787 chr6:26556769 G/T cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.716 rs34487581 chr10:897201 G/A cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs769267 1.000 rs2074090 chr19:19449686 G/T cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs2742234 0.910 rs2505505 chr10:43648221 G/T cg02780029 chr10:43622663 RET -0.26 -5.05 -0.41 1.57e-6 Hirschsprung disease; TGCT cis rs7829975 0.623 rs7010753 chr8:8373956 A/G cg08975724 chr8:8085496 FLJ10661 0.58 5.42 0.44 2.99e-7 Mood instability; TGCT cis rs1044826 0.692 rs295484 chr3:139231782 A/G cg00490450 chr3:139108681 COPB2 -0.52 -4.6 -0.38 1.04e-5 Obesity-related traits; TGCT cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg05985448 chr10:134359359 INPP5A 0.22 4.82 0.4 4.12e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1878931 0.624 rs27235 chr16:3439138 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.77 -6.51 -0.5 1.66e-9 Body mass index (adult); TGCT cis rs3733585 0.673 rs4697914 chr4:9952266 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.65 -0.57 4.78e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4722166 0.603 rs7801406 chr7:22788274 A/G cg26061582 chr7:22766209 IL6 0.58 7.34 0.55 2.49e-11 Lung cancer; TGCT cis rs11098499 0.909 rs7659501 chr4:120371552 G/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs2836974 0.831 rs34592564 chr21:40516288 G/C cg11644478 chr21:40555479 PSMG1 1.0 10.38 0.68 1.5e-18 Cognitive function; TGCT cis rs9787249 0.915 rs6664570 chr1:40206298 G/A cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs6570726 0.791 rs11155435 chr6:145938545 T/C cg13319975 chr6:146136371 FBXO30 -0.53 -4.75 -0.39 5.62e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg11062466 chr8:58055876 NA 0.44 4.62 0.38 9.46e-6 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.887 rs7503395 chr17:29440554 C/T cg24425628 chr17:29625626 OMG;NF1 0.46 7.17 0.54 6.01e-11 Hip circumference; TGCT cis rs10479542 0.702 rs13183521 chr5:178975606 A/G cg09060608 chr5:178986726 RUFY1 -0.47 -5.4 -0.44 3.22e-7 Lung cancer; TGCT cis rs769267 0.965 rs2023882 chr19:19405405 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs950027 0.620 rs35861938 chr15:45637343 T/C cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs13401104 0.587 rs6431443 chr2:237150311 T/C cg19324714 chr2:237145437 ASB18 0.44 4.62 0.38 9.29e-6 Educational attainment; TGCT cis rs2120019 0.938 rs3850093 chr15:75318482 A/G cg17294928 chr15:75287854 SCAMP5 0.8 5.92 0.47 3e-8 Blood trace element (Zn levels); TGCT cis rs7000551 0.505 rs73227818 chr8:22243325 T/C cg12081754 chr8:22256438 SLC39A14 0.32 4.58 0.38 1.09e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9807989 0.811 rs11688559 chr2:102969913 C/T cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs12286929 0.637 rs34138164 chr11:115050127 A/G cg04017736 chr11:115827165 NA -0.2 -4.6 -0.38 1.04e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs58950470 0.521 rs7950197 chr11:65446126 T/C cg27068330 chr11:65405492 SIPA1 -0.51 -4.67 -0.39 7.86e-6 Schizophrenia; TGCT cis rs797680 0.891 rs4847399 chr1:93584606 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.12 -0.42 1.14e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1580019 0.922 rs34545272 chr7:32460630 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.78 7.39 0.55 1.9e-11 Cognitive ability; TGCT cis rs6088580 0.634 rs6059887 chr20:33101102 C/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg03060546 chr3:49711283 APEH 0.53 5.14 0.42 1.05e-6 Menarche (age at onset); TGCT cis rs11148252 0.904 rs9568734 chr13:53004222 G/A cg00495681 chr13:53174319 NA 0.59 6.08 0.48 1.39e-8 Lewy body disease; TGCT cis rs7267979 0.586 rs1473695 chr20:25186965 A/G cg03522245 chr20:25566470 NINL 0.5 5.24 0.43 6.66e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11098499 0.909 rs6842762 chr4:120398236 A/T cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs41271473 0.500 rs4440831 chr1:228887522 C/T cg10167378 chr1:228756711 NA -0.56 -4.83 -0.4 3.93e-6 Chronic lymphocytic leukemia; TGCT cis rs908922 0.676 rs1856120 chr1:152512441 G/A cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs9388451 0.807 rs1268070 chr6:126041164 A/G cg10911889 chr6:126070802 HEY2 0.56 5.38 0.43 3.59e-7 Brugada syndrome; TGCT cis rs1218582 0.772 rs4240875 chr1:154885782 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs875971 0.893 rs62465470 chr7:65601218 T/C cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.99e-6 Aortic root size; TGCT cis rs950027 0.620 rs1617634 chr15:45615578 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 6.08 0.48 1.35e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs9303401 0.659 rs12940212 chr17:56674474 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7647973 0.769 rs4974081 chr3:49070499 A/G cg05785598 chr3:49045655 WDR6 -0.39 -4.52 -0.38 1.42e-5 Menarche (age at onset); TGCT cis rs7582180 0.764 rs12615466 chr2:100924065 C/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.523 rs7781947 chr7:106902219 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs1218582 0.661 rs4845695 chr1:154911798 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.64 -6.58 -0.51 1.21e-9 Prostate cancer; TGCT cis rs921968 0.678 rs689116 chr2:219433888 C/A cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs41307935 0.730 rs12753968 chr1:27197363 C/T cg23921621 chr1:27994728 IFI6 -0.42 -4.59 -0.38 1.06e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs637571 0.584 rs659824 chr11:65636509 A/G cg26695010 chr11:65641043 EFEMP2 0.58 6.02 0.48 1.8e-8 Eosinophil percentage of white cells; TGCT cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs7474896 0.559 rs1024202 chr10:38278977 A/C cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs11031096 0.782 rs10835684 chr11:4168308 G/T cg18678763 chr11:4115507 RRM1 -0.46 -5.79 -0.46 5.36e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg25151919 chr3:44754333 ZNF502 -0.43 -4.96 -0.41 2.31e-6 Depressive symptoms; TGCT cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs12549902 1.000 rs12550613 chr8:41510260 G/C cg00088007 chr8:41504566 NKX6-3 0.34 5.38 0.43 3.59e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs6121246 0.567 rs6120937 chr20:30219721 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg00024416 chr22:24240387 NA 0.35 5.93 0.47 2.79e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs11577318 0.538 rs10902745 chr1:26687070 G/C cg15090202 chr1:26687087 NA 0.58 4.49 0.37 1.64e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2663905 0.664 rs2460855 chr15:81361729 G/T cg09888468 chr15:81410853 NA -0.62 -5.03 -0.41 1.68e-6 QT interval (drug interaction); TGCT cis rs7666738 0.830 rs11097600 chr4:98959564 T/G cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs739496 0.527 rs4767074 chr12:112292962 G/C cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs7809950 1.000 rs10251808 chr7:107120453 G/A cg23024343 chr7:107201750 COG5 -0.34 -5.33 -0.43 4.54e-7 Coronary artery disease; TGCT cis rs1348850 0.914 rs1453370 chr2:178327727 C/T cg22681709 chr2:178499509 PDE11A -0.35 -4.6 -0.38 1.01e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9457247 0.905 rs444210 chr6:167390242 A/G cg23791538 chr6:167370224 RNASET2 -0.51 -4.93 -0.4 2.63e-6 Crohn's disease; TGCT cis rs34526934 0.566 rs1374325 chr2:177043971 G/A cg26754761 chr2:177040938 NA -0.29 -5.39 -0.44 3.35e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs6770219 0.516 rs11922843 chr3:186135875 T/C cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs9611565 0.694 rs9611591 chr22:41830212 G/A cg06634786 chr22:41940651 POLR3H 0.82 7.92 0.58 1.16e-12 Vitiligo; TGCT cis rs1670533 0.929 rs6599280 chr4:1063818 A/G cg20887711 chr4:1340912 KIAA1530 0.69 5.54 0.45 1.72e-7 Recombination rate (females); TGCT cis rs1887596 0.554 rs4770995 chr13:27112522 C/T cg01312412 chr13:27282625 NA 0.26 4.54 0.38 1.3e-5 Facial morphology (factor 3, length of philtrum); TGCT cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg26818010 chr10:134567672 INPP5A -0.39 -5.51 -0.44 1.94e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs473651 0.935 rs541013 chr2:239336492 G/A cg18131467 chr2:239335373 ASB1 1.03 15.25 0.81 3.21e-30 Multiple system atrophy; TGCT cis rs231513 0.911 rs124719 chr17:41960343 T/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT trans rs1005277 0.579 rs2021649 chr10:38392122 C/T cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs9660180 0.967 rs6603802 chr1:1812521 C/T cg03396347 chr1:1875803 NA -0.4 -7.31 -0.55 2.86e-11 Body mass index; TGCT cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg27211696 chr2:191398769 TMEM194B -0.27 -5.07 -0.41 1.42e-6 Pulse pressure; TGCT cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg14114931 chr22:50943910 LMF2 0.41 4.98 0.41 2.09e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9926296 0.565 rs8055825 chr16:89832848 C/T cg21285383 chr16:89894308 SPIRE2 0.43 6.85 0.52 3e-10 Vitiligo; TGCT cis rs4689388 0.926 rs4688987 chr4:6287329 C/T cg00701064 chr4:6280414 WFS1 0.45 6.0 0.47 1.98e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs514406 0.621 rs2003250 chr1:53196666 T/C cg01802117 chr1:53393560 SCP2 0.42 4.92 0.4 2.69e-6 Monocyte count; TGCT cis rs10114408 0.959 rs10821257 chr9:96657294 C/A cg13679303 chr9:96623674 NA -0.36 -4.73 -0.39 5.91e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs4819052 0.851 rs28616694 chr21:46674786 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.55 0.38 1.27e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg06481639 chr22:41940642 POLR3H 0.71 6.35 0.5 3.62e-9 Vitiligo; TGCT cis rs2952156 0.920 rs732083 chr17:37834367 G/A cg20243544 chr17:37824526 PNMT 0.51 4.48 0.37 1.65e-5 Asthma; TGCT cis rs9910055 0.920 rs2855818 chr17:42290015 G/A cg13607699 chr17:42295918 UBTF 0.89 7.97 0.58 8.86e-13 Total body bone mineral density; TGCT cis rs1541995 1.000 rs34567257 chr15:96304856 G/C cg00882281 chr15:96346592 NA 0.29 4.68 0.39 7.26e-6 Photic sneeze reflex; TGCT cis rs12291225 0.679 rs11023178 chr11:14310282 G/A cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs263156 0.967 rs263104 chr6:142875919 C/G cg18419694 chr6:143832440 FUCA2 0.38 4.47 0.37 1.75e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs9467711 0.606 rs35307327 chr6:26370474 C/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1532993 0.518 rs28408794 chr4:98625714 G/C cg05340658 chr4:99064831 C4orf37 -0.37 -4.44 -0.37 1.98e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs7043114 0.563 rs987554 chr9:95298738 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.25 -0.43 6.26e-7 Height; TGCT cis rs9902453 0.934 rs7213902 chr17:28322935 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.75 6.55 0.51 1.36e-9 Coffee consumption (cups per day); TGCT cis rs7267979 0.789 rs2260197 chr20:25284343 T/C cg03522245 chr20:25566470 NINL 0.52 5.23 0.43 6.85e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs67311347 0.955 rs73080163 chr3:40533061 G/T cg13409248 chr3:40428643 ENTPD3 0.64 4.91 0.4 2.77e-6 Renal cell carcinoma; TGCT cis rs916888 0.610 rs142167 chr17:44795234 C/T cg15921436 chr17:44337874 NA -0.4 -5.98 -0.47 2.23e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs35146811 0.695 rs858508 chr7:99821381 C/G cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs7267979 0.932 rs417130 chr20:25458320 T/C cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg05985448 chr10:134359359 INPP5A 0.21 4.71 0.39 6.56e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4891159 0.756 rs55763305 chr18:74161249 G/C cg24786174 chr18:74118243 ZNF516 -0.48 -6.25 -0.49 5.97e-9 Longevity; TGCT cis rs1552244 0.554 rs4488814 chr3:10002400 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 0.31 4.77 0.39 5.14e-6 Alzheimer's disease; TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg14893161 chr1:205819251 PM20D1 0.56 7.96 0.58 9.21e-13 Menarche (age at onset); TGCT cis rs7833790 0.724 rs6473309 chr8:82707880 A/G cg23324259 chr8:82754387 SNX16 -0.66 -5.08 -0.41 1.36e-6 Diastolic blood pressure; TGCT cis rs2153535 0.580 rs7741456 chr6:8452424 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs6088580 0.634 rs6059829 chr20:33017074 G/A cg24642439 chr20:33292090 TP53INP2 0.49 4.51 0.38 1.5e-5 Glomerular filtration rate (creatinine); TGCT cis rs9527 0.545 rs12247514 chr10:104958066 C/A cg15744005 chr10:104629667 AS3MT -0.41 -4.78 -0.39 4.88e-6 Arsenic metabolism; TGCT cis rs200810 0.694 rs13218275 chr6:97998314 C/T cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.65 -4.45 -0.37 1.91e-5 Body mass index; TGCT trans rs17684571 0.938 rs13196211 chr6:56562495 C/T cg14229071 chr15:89282588 NA 0.52 6.82 0.52 3.54e-10 Schizophrenia; TGCT cis rs7246657 0.765 rs4803262 chr19:38066760 G/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs3764563 0.877 rs4646526 chr19:15729773 A/G cg20725493 chr19:15740067 CYP4F8 -0.46 -5.06 -0.41 1.5e-6 Inflammatory biomarkers; TGCT cis rs12893668 0.581 rs34843146 chr14:104079864 G/A cg26031613 chr14:104095156 KLC1 -0.55 -4.64 -0.38 8.81e-6 Reticulocyte count; TGCT cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs17152411 1.000 rs7097282 chr10:126593492 T/C cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs9796 0.804 rs28688742 chr15:41403638 G/A cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.88 -0.53 2.64e-10 Menopause (age at onset); TGCT cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg13342137 chr4:2252803 MXD4 0.17 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs36051895 0.594 rs10115464 chr9:5144268 C/T cg02405213 chr9:5042618 JAK2 -0.74 -10.39 -0.68 1.4e-18 Pediatric autoimmune diseases; TGCT trans rs7618501 1.000 rs6446295 chr3:49809063 G/T cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs7027203 0.790 rs10123836 chr9:96584109 G/T cg13679303 chr9:96623674 NA -0.66 -10.64 -0.69 3.54e-19 DNA methylation (variation); TGCT cis rs7826238 0.543 rs2976908 chr8:8345774 T/G cg15556689 chr8:8085844 FLJ10661 0.65 5.8 0.46 5.2100000000000003e-08 Systolic blood pressure; TGCT cis rs853679 0.517 rs9368558 chr6:28133306 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs78487399 0.808 rs13419380 chr2:43739184 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9921222 1.000 rs9921222 chr16:375782 A/G cg12437481 chr16:420112 MRPL28 0.48 5.09 0.42 1.29e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs10789491 1.000 rs10749863 chr1:47174328 C/T cg15501359 chr1:47185051 KIAA0494 0.81 8.37 0.6 9.97e-14 Response to hepatitis C treatment; TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg14159672 chr1:205819179 PM20D1 0.6 7.44 0.56 1.45e-11 Menarche (age at onset); TGCT cis rs707040 0.921 rs2037663 chr2:155231057 T/C cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs9807989 0.507 rs4851579 chr2:103028984 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.18e-7 Asthma; TGCT cis rs4689388 0.926 rs4234730 chr4:6296343 A/G cg14416269 chr4:6271139 WFS1 0.38 4.94 0.41 2.47e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6582630 0.593 rs12816835 chr12:38533304 C/T cg26384229 chr12:38710491 ALG10B -0.53 -4.78 -0.39 4.9100000000000004e-06 Drug-induced liver injury (flucloxacillin); TGCT cis rs8177253 0.898 rs8177258 chr3:133480387 C/A cg20276088 chr3:133502917 NA -0.24 -5.05 -0.41 1.53e-6 Iron status biomarkers; TGCT cis rs2463822 0.925 rs74692811 chr11:62156572 G/A cg23876832 chr11:62092739 NA -0.63 -4.68 -0.39 7.29e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7312933 0.558 rs1796388 chr12:42785987 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.69 -0.46 8.61e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs769267 0.965 rs2074296 chr19:19373689 A/G cg19010396 chr19:19431384 KIAA0892;SF4 0.56 4.63 0.38 9.06e-6 Tonsillectomy; TGCT cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg18402987 chr7:1209562 NA 0.74 6.19 0.49 7.92e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3806843 0.551 rs246018 chr5:140335043 T/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs2469997 0.925 rs2470005 chr8:120358483 T/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs6089584 0.962 rs6142913 chr20:60566950 A/G cg06108461 chr20:60628389 TAF4 -0.61 -8.83 -0.62 8.24e-15 Body mass index; TGCT cis rs9427116 0.840 rs9427113 chr1:154626477 A/G cg17218026 chr1:154582156 ADAR 0.26 6.24 0.49 6.39e-9 Blood protein levels; TGCT cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg03517284 chr6:25882590 NA -0.47 -4.73 -0.39 5.95e-6 Height; TGCT cis rs6981523 0.566 rs34162231 chr8:11003088 A/T cg21775007 chr8:11205619 TDH -0.58 -5.41 -0.44 3.09e-7 Neuroticism; TGCT cis rs6089584 0.821 rs4925332 chr20:60604639 C/T cg13665807 chr20:60559372 TAF4 -0.43 -4.66 -0.39 7.92e-6 Body mass index; TGCT cis rs7208859 0.623 rs216445 chr17:28933576 A/G cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs17685 0.753 rs10264760 chr7:75749694 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7044106 0.708 rs1324472 chr9:123375110 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.42 4.61 0.38 9.68e-6 Hip circumference adjusted for BMI; TGCT cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg11494091 chr17:61959527 GH2 -0.53 -11.98 -0.73 1.94e-22 Prudent dietary pattern; TGCT cis rs4820539 0.902 rs737846 chr22:23460669 A/G cg14186256 chr22:23484241 RTDR1 0.99 12.45 0.75 1.36e-23 Bone mineral density; TGCT cis rs7575217 0.767 rs62152486 chr2:101745835 A/C cg12737833 chr2:101500543 NPAS2 0.28 4.58 0.38 1.09e-5 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; TGCT trans rs7613875 0.600 rs2247510 chr3:50126215 A/C cg21665057 chr3:196295764 WDR53;FBXO45 0.85 8.89 0.62 6.01e-15 Body mass index; TGCT cis rs854765 0.929 rs854766 chr17:18012775 A/G cg09796270 chr17:17721594 SREBF1 0.27 5.31 0.43 4.87e-7 Total body bone mineral density; TGCT cis rs7917772 0.636 rs4919676 chr10:104524352 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.56 -4.59 -0.38 1.07e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg20887711 chr4:1340912 KIAA1530 0.85 7.27 0.55 3.48e-11 Longevity; TGCT cis rs12701220 0.894 rs10257744 chr7:1045612 C/T cg07217954 chr7:1067459 C7orf50 -0.48 -4.75 -0.39 5.49e-6 Bronchopulmonary dysplasia; TGCT cis rs7824557 0.767 rs718427 chr8:11139038 C/G cg21775007 chr8:11205619 TDH 0.6 5.65 0.45 1.03e-7 Retinal vascular caliber; TGCT trans rs1005277 0.691 rs2474558 chr10:38486141 A/C cg17830980 chr10:43048298 ZNF37B 0.71 6.94 0.53 1.89e-10 Extrinsic epigenetic age acceleration; TGCT cis rs6087990 0.735 rs1040554 chr20:31380073 C/T cg13636640 chr20:31349939 DNMT3B 0.97 13.01 0.76 6.33e-25 Ulcerative colitis; TGCT cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg13665807 chr20:60559372 TAF4 -0.53 -5.41 -0.44 3.06e-7 Body mass index; TGCT cis rs10875746 0.859 rs11168371 chr12:48437686 C/T cg20731937 chr12:48336164 NA 0.57 4.48 0.37 1.69e-5 Longevity (90 years and older); TGCT cis rs7172809 0.599 rs2307141 chr15:77756418 A/G cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs4951018 0.821 rs7529037 chr1:205637501 C/G cg26354017 chr1:205819088 PM20D1 -0.4 -4.72 -0.39 6.23e-6 Prostate-specific antigen levels; TGCT trans rs629535 0.814 rs651985 chr8:70054966 G/A cg21567404 chr3:27674614 NA 0.57 8.62 0.61 2.68e-14 Dupuytren's disease; TGCT cis rs4273100 1.000 rs868698 chr17:19185211 G/T cg01534423 chr17:18965556 NA 0.91 6.0 0.47 2.05e-8 Schizophrenia; TGCT cis rs6061231 0.624 rs8668 chr20:60964064 C/T cg15674680 chr20:60982522 CABLES2 -0.62 -5.21 -0.42 7.68e-7 Colorectal cancer; TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg08859206 chr1:53392774 SCP2 -0.46 -6.97 -0.53 1.62e-10 Monocyte count; TGCT cis rs5750830 0.649 rs5750818 chr22:39820885 A/G cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs1580019 0.534 rs13237495 chr7:32560687 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.14 14.68 0.8 6.88e-29 Cognitive ability; TGCT cis rs10493773 0.775 rs12739713 chr1:86150378 C/T cg17807903 chr1:86174739 ZNHIT6 -0.43 -6.07 -0.48 1.47e-8 Urate levels in overweight individuals; TGCT cis rs7904368 0.901 rs7923189 chr10:16850214 C/T cg14835575 chr10:16859367 RSU1 0.63 6.79 0.52 4.07e-10 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs1385374 1.000 rs1385374 chr12:129300694 C/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs11874712 0.965 rs8085444 chr18:43652203 G/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.16 0.42 9.44e-7 Migraine - clinic-based; TGCT cis rs601339 0.938 rs1696345 chr12:123183060 T/G cg11919336 chr12:123188078 GPR109A 0.64 7.74 0.57 3.07e-12 Adiponectin levels; TGCT cis rs10465746 0.935 rs12406984 chr1:84416215 C/G cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg14893161 chr1:205819251 PM20D1 0.57 8.17 0.59 2.97e-13 Menarche (age at onset); TGCT cis rs317689 0.690 rs317630 chr12:69637847 T/C cg14784868 chr12:69753453 YEATS4 0.54 4.46 0.37 1.84e-5 Response to diuretic therapy; TGCT cis rs60843830 0.928 rs2306060 chr2:230912 A/C cg00108164 chr2:264199 ACP1;SH3YL1 0.75 7.17 0.54 5.87e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 5.25 0.43 6.47e-7 Height; TGCT cis rs7666738 0.800 rs7684523 chr4:98983175 G/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs344364 0.511 rs1742462 chr16:1946062 A/C cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs4788570 0.615 rs1058750 chr16:71679057 C/T cg06353428 chr16:71660113 MARVELD3 1.54 12.33 0.74 2.73e-23 Intelligence (multi-trait analysis); TGCT cis rs72781680 0.821 rs72796369 chr2:24162663 G/T cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs2180341 0.960 rs7751865 chr6:127683040 G/A cg24812749 chr6:127587940 RNF146 0.93 7.4 0.55 1.83e-11 Breast cancer; TGCT cis rs7940866 0.845 rs1991899 chr11:130801649 C/T cg05962950 chr11:130786565 SNX19 -0.63 -6.38 -0.5 3.13e-9 Schizophrenia; TGCT cis rs8078723 1.000 rs3213762 chr17:38178627 A/G cg17467752 chr17:38218738 THRA 0.52 4.94 0.41 2.47e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs1903068 1.000 rs9312658 chr4:56005526 C/A cg16572876 chr4:56024045 NA 0.46 5.23 0.42 7.13e-7 Endometriosis; TGCT cis rs514406 0.861 rs554760 chr1:53266749 G/A cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs561341 0.739 rs7213369 chr17:30211878 G/A cg13647721 chr17:30228624 UTP6 -0.61 -4.8 -0.4 4.39e-6 Hip circumference adjusted for BMI; TGCT cis rs763121 0.853 rs35565791 chr22:39063011 C/A cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs6700896 0.500 rs4655564 chr1:66083537 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs453301 0.606 rs7462373 chr8:8899318 G/C cg06636001 chr8:8085503 FLJ10661 -0.7 -5.86 -0.47 3.9e-8 Joint mobility (Beighton score); TGCT cis rs6429082 0.715 rs2291687 chr1:235594182 A/G cg26050004 chr1:235667680 B3GALNT2 -0.54 -4.77 -0.39 5.07e-6 Adiposity; TGCT cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg03264133 chr6:25882463 NA -0.68 -7.58 -0.56 7e-12 Blood metabolite levels; TGCT cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs3099143 0.901 rs78020233 chr15:77107050 T/G cg21673338 chr15:77095150 SCAPER -0.48 -4.47 -0.37 1.77e-5 Recalcitrant atopic dermatitis; TGCT cis rs644799 0.562 rs1254989 chr11:95508121 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.58 6.24 0.49 6.43e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs514406 0.505 rs425520 chr1:53179805 C/G cg01802117 chr1:53393560 SCP2 -0.4 -4.75 -0.39 5.55e-6 Monocyte count; TGCT cis rs9913156 0.894 rs35741745 chr17:4620897 A/G cg19197139 chr17:4613644 ARRB2 0.86 7.84 0.58 1.73e-12 Lymphocyte counts; TGCT cis rs2932538 0.922 rs6663922 chr1:113095948 T/C cg22162597 chr1:113214053 CAPZA1 0.25 5.5 0.44 2.06e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7666738 0.791 rs60028147 chr4:99046618 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4689388 0.889 rs13128674 chr4:6294517 C/T cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2204008 0.837 rs73112346 chr12:38357606 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.25 0.55 4e-11 Bladder cancer; TGCT cis rs7100689 0.577 rs1417219 chr10:82041409 C/T cg01528321 chr10:82214614 TSPAN14 0.7 6.78 0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs6500602 0.727 rs8051389 chr16:4570570 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.95 0.47 2.54e-8 Schizophrenia; TGCT cis rs2887571 1.000 rs4283041 chr12:1637913 C/T cg01940102 chr12:1095972 NA 0.24 4.7 0.39 6.93e-6 Bone mineral density; TGCT cis rs10465746 0.725 rs10127737 chr1:84368642 G/A cg10977910 chr1:84465055 TTLL7 0.68 6.7 0.52 6.46e-10 Obesity-related traits; TGCT cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg17328964 chr8:145687451 CYHR1 0.45 6.21 0.49 7.44e-9 Age at first birth; TGCT cis rs7833790 0.660 rs10091077 chr8:82705464 A/G cg27398817 chr8:82754497 SNX16 -0.6 -4.67 -0.39 7.62e-6 Diastolic blood pressure; TGCT cis rs9611565 0.879 rs4820437 chr22:41761290 T/C cg03806693 chr22:41940476 POLR3H -1.02 -11.06 -0.7 3.31e-20 Vitiligo; TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.51 4.48 0.37 1.68e-5 Prudent dietary pattern; TGCT cis rs12142240 0.698 rs7515284 chr1:46809419 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg09904177 chr6:26538194 HMGN4 0.67 6.32 0.49 4.25e-9 Intelligence (multi-trait analysis); TGCT trans rs916888 0.773 rs199439 chr17:44793503 A/G cg07870213 chr5:140052090 DND1 0.67 7.91 0.58 1.22e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7584330 0.910 rs6737914 chr2:238393434 A/G cg16989719 chr2:238392110 NA -0.26 -4.53 -0.38 1.35e-5 Prostate cancer; TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg07167872 chr1:205819463 PM20D1 0.53 6.71 0.52 6.24e-10 Monocyte percentage of white cells; TGCT cis rs2180341 1.000 rs6910763 chr6:127630925 T/C cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs6933660 0.646 rs9383899 chr6:151781022 G/C cg10883421 chr6:151773342 RMND1;C6orf211 0.73 7.65 0.57 4.75e-12 Menarche (age at onset); TGCT cis rs78707713 0.512 rs35793747 chr10:71182165 A/G cg12610070 chr10:71211762 TSPAN15 -0.59 -6.87 -0.52 2.82e-10 Venous thromboembolism; TGCT cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs7474896 0.522 rs117157955 chr10:37984164 G/T cg13720705 chr10:37990370 NA 0.34 5.0 0.41 1.89e-6 Obesity (extreme); TGCT cis rs1992660 0.523 rs12697408 chr5:40348573 T/A cg01087697 chr5:40835557 RPL37 0.52 4.7 0.39 6.92e-6 Crohn's disease; TGCT cis rs9902453 0.845 rs12602426 chr17:28158815 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs3947 0.813 rs1293316 chr8:11690915 A/G cg02840367 chr8:11660030 FDFT1 0.92 6.56 0.51 1.3e-9 Blood protein levels; TGCT cis rs675531 0.574 rs9482835 chr6:128054748 C/G cg11613741 chr6:127780352 KIAA0408;C6orf174 0.25 4.48 0.37 1.66e-5 Recalcitrant atopic dermatitis; TGCT trans rs1814175 0.935 rs7482690 chr11:49648814 C/T cg15704280 chr7:45808275 SEPT13 -0.61 -6.75 -0.52 5e-10 Height; TGCT trans rs2243480 0.901 rs13237344 chr7:66022256 T/A cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs1682825 0.858 rs76037015 chr3:10761118 G/A cg23512531 chr3:10780469 NA 0.62 4.53 0.38 1.36e-5 Economic and political preferences (feminism/equality); TGCT cis rs3733585 0.699 rs28610447 chr4:9971517 T/C cg00071950 chr4:10020882 SLC2A9 -0.57 -6.83 -0.52 3.41e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4253772 0.592 rs1807600 chr22:46644640 A/G cg09491104 chr22:46646882 C22orf40 -0.51 -5.43 -0.44 2.86e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9896933 0.832 rs77512810 chr17:80804589 C/T cg20578329 chr17:80767326 TBCD -0.35 -4.99 -0.41 1.99e-6 Bone mineral accretion in asthma (oral corticosteroid dose interaction); TGCT cis rs2180341 0.842 rs9375492 chr6:127545492 C/T cg24812749 chr6:127587940 RNF146 -0.89 -6.27 -0.49 5.61e-9 Breast cancer; TGCT cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12477438 1.000 rs6732980 chr2:99921613 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.8 -6.4 -0.5 2.91e-9 Chronic sinus infection; TGCT cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.73e-6 Obesity-related traits; TGCT cis rs6582630 0.562 rs35080195 chr12:38310866 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.67 -0.39 7.55e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg11890956 chr21:40555474 PSMG1 -0.7 -6.8 -0.52 3.87e-10 Menarche (age at onset); TGCT cis rs7666738 0.830 rs1426672 chr4:98923984 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6076065 0.748 rs1016628 chr20:23398738 C/G cg11657817 chr20:23433608 CST11 -0.31 -5.47 -0.44 2.42e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs6121246 0.523 rs6060286 chr20:30197663 C/A cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs12142240 0.698 rs3991877 chr1:46853749 C/A cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs8179 0.700 rs42041 chr7:92246744 C/G cg15732164 chr7:92237376 CDK6 -0.29 -5.01 -0.41 1.84e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs6460942 0.915 rs7803056 chr7:12306913 A/C cg06484146 chr7:12443880 VWDE -0.45 -4.68 -0.39 7.41e-6 Coronary artery disease; TGCT cis rs2486288 0.656 rs12910009 chr15:45572408 A/G cg26924012 chr15:45694286 SPATA5L1 -0.79 -7.73 -0.57 3.24e-12 Glomerular filtration rate; TGCT cis rs7705042 0.686 rs10068466 chr5:141524612 C/T cg07392085 chr5:141489673 NDFIP1 -0.34 -4.57 -0.38 1.15e-5 Asthma; TGCT cis rs933688 1.000 rs12651840 chr5:90729592 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.97 8.61 0.61 2.82e-14 Smoking behavior; TGCT cis rs12477438 0.765 rs2309521 chr2:99592069 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs4742903 0.868 rs4743684 chr9:106852385 A/C cg21169611 chr9:106856078 SMC2 0.49 4.48 0.37 1.69e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs4824093 0.535 rs73441802 chr22:50273916 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.5 5.14 0.42 1.05e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9467773 1.000 rs9393728 chr6:26509330 C/G cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT trans rs62103177 0.673 rs55852342 chr18:77594109 G/C cg05926928 chr17:57297772 GDPD1 1.04 9.91 0.66 2.12e-17 Opioid sensitivity; TGCT cis rs7017914 0.934 rs13274062 chr8:71737087 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs9467711 0.659 rs3734542 chr6:26468326 G/A cg16898833 chr6:26189333 HIST1H4D 1.13 5.05 0.41 1.56e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1371867 0.846 rs1788197 chr8:101290928 T/C cg06636551 chr8:101224915 SPAG1 -0.43 -5.95 -0.47 2.58e-8 Atrioventricular conduction; TGCT trans rs2469997 0.925 rs2447180 chr8:120355728 T/G cg01792902 chr3:178864926 PIK3CA 0.78 6.66 0.51 7.93e-10 Hypertension (SNP x SNP interaction); TGCT cis rs1048238 0.506 rs598371 chr1:16212739 G/A cg21385522 chr1:16154831 NA -0.58 -6.36 -0.5 3.57e-9 Systolic blood pressure; TGCT cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg07061783 chr6:25882402 NA -0.41 -4.45 -0.37 1.89e-5 Height; TGCT cis rs769267 0.930 rs7254748 chr19:19397479 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs208520 0.690 rs176289 chr6:66766522 C/T cg07460842 chr6:66804631 NA -0.96 -10.32 -0.68 2.1e-18 Exhaled nitric oxide output; TGCT cis rs3829109 0.564 rs11145889 chr9:139293843 A/G cg13741927 chr9:139327495 INPP5E -0.24 -5.18 -0.42 8.84e-7 Peak insulin response;Acute insulin response; TGCT cis rs926938 0.563 rs360630 chr1:115415132 C/T cg12756093 chr1:115239321 AMPD1 0.41 6.44 0.5 2.37e-9 Autism; TGCT trans rs6089829 1.000 rs62207535 chr20:61669187 A/G cg13615516 chr5:77269221 NA 0.72 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg13607699 chr17:42295918 UBTF -0.91 -8.08 -0.59 4.8e-13 Total body bone mineral density; TGCT trans rs916888 0.610 rs199436 chr17:44789285 C/T cg22968622 chr17:43663579 NA -0.99 -9.95 -0.67 1.71e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs10875595 0.836 rs12187725 chr5:140662912 A/G cg24830062 chr5:140700576 TAF7 -0.75 -6.28 -0.49 5.28e-9 Pulmonary function decline; TGCT cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs6540559 1.000 rs2073485 chr1:209962794 G/A cg04352962 chr1:209979756 IRF6 0.61 4.67 0.39 7.72e-6 Cleft lip with or without cleft palate; TGCT cis rs2836633 0.929 rs11702165 chr21:40035313 C/T cg12884169 chr21:40033163 ERG 0.43 4.69 0.39 7.03e-6 Coronary artery disease; TGCT cis rs7829975 0.577 rs940032 chr8:8546343 C/T cg17143192 chr8:8559678 CLDN23 -0.52 -5.29 -0.43 5.45e-7 Mood instability; TGCT cis rs2832191 0.967 rs2251377 chr21:30530599 T/C cg08807101 chr21:30365312 RNF160 0.52 4.71 0.39 6.57e-6 Dental caries; TGCT trans rs1814175 0.645 rs847639 chr11:49919603 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs73110464 0.609 rs11170348 chr12:53355588 A/G cg16329197 chr12:53359506 NA -0.56 -7.89 -0.58 1.32e-12 Cancer (pleiotropy); TGCT cis rs7635838 0.684 rs346079 chr3:11328139 G/A cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs7666738 0.830 rs11947578 chr4:98930462 T/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7193541 0.684 rs4887783 chr16:74700743 G/C cg01733217 chr16:74700730 RFWD3 1.02 14.66 0.8 7.69e-29 Multiple myeloma; TGCT cis rs986417 1.000 rs1254332 chr14:60916587 T/C cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg25660036 chr4:7070649 GRPEL1 -0.67 -5.81 -0.46 4.85e-8 Monocyte percentage of white cells; TGCT cis rs17221829 0.733 rs12421374 chr11:89381067 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs7072216 0.763 rs10748729 chr10:100171371 G/C cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs13191362 1.000 rs13202339 chr6:163081812 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.97 0.53 1.69e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6964587 1.000 rs17164275 chr7:91590408 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs11722228 1.000 rs4697695 chr4:9915850 C/T cg00071950 chr4:10020882 SLC2A9 0.5 4.86 0.4 3.51e-6 Gout;Urate levels;Serum uric acid levels; TGCT cis rs2963155 0.518 rs2918419 chr5:142722353 T/C cg17617527 chr5:142782415 NR3C1 0.84 6.18 0.49 8.6e-9 Breast cancer; TGCT cis rs56114371 0.530 rs9357045 chr6:27688927 G/A cg10876282 chr6:28092338 ZSCAN16 0.64 5.29 0.43 5.39e-7 Breast cancer; TGCT cis rs7943191 0.810 rs7942154 chr11:62337163 G/A cg22862634 chr11:62369728 EML3;MTA2 0.59 5.99 0.47 2.11e-8 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg03188948 chr7:1209495 NA 0.45 5.85 0.47 4.04e-8 Longevity;Endometriosis; TGCT cis rs950776 0.545 rs34275594 chr15:78981282 A/C cg03762349 chr15:79060523 ADAMTS7 0.28 5.94 0.47 2.73e-8 Sudden cardiac arrest; TGCT cis rs7552404 0.731 rs61770556 chr1:76421902 T/C cg03433033 chr1:76189801 ACADM 0.73 6.67 0.51 7.74e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs875971 1.000 rs7789768 chr7:65938980 A/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs666930 0.519 rs662602 chr1:120266903 C/G cg19096424 chr1:120255104 PHGDH 0.62 5.63 0.45 1.17e-7 Breast cancer; TGCT cis rs8077889 0.700 rs28571770 chr17:41904066 A/T cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT trans rs116975820 0.698 rs11181503 chr12:42827697 A/G cg26084949 chr14:75039090 LTBP2 -0.76 -6.74 -0.52 5.2400000000000005e-10 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs651907 0.535 rs11712309 chr3:101519097 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs60843830 0.633 rs1078763 chr2:113763 A/G cg00108164 chr2:264199 ACP1;SH3YL1 -0.53 -4.51 -0.38 1.47e-5 Spherical equivalent (joint analysis main effects and education interaction); TGCT trans rs1814175 0.817 rs10769618 chr11:49822336 A/G cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs644799 0.965 rs545342 chr11:95545369 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2842992 0.830 rs1475123 chr6:160178007 A/G cg11366901 chr6:160182831 ACAT2 1.01 6.79 0.52 4.21e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs3845702 1.000 rs3738943 chr2:180846743 G/T cg01881094 chr2:180872142 CWC22 -0.68 -6.01 -0.47 1.93e-8 Schizophrenia; TGCT cis rs7714584 1.000 rs11749391 chr5:150229066 T/C cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs3540 0.597 rs11639150 chr15:91042071 C/G cg22089800 chr15:90895588 ZNF774 -0.75 -7.58 -0.56 6.96e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2413583 0.591 rs75378967 chr22:39735210 T/G cg24399712 chr22:39784796 NA 0.82 4.48 0.37 1.69e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs67311347 1.000 rs2887995 chr3:40409029 C/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs4654899 0.865 rs6685831 chr1:21507888 G/A cg01072550 chr1:21505969 NA -0.48 -7.14 -0.54 7.03e-11 Superior frontal gyrus grey matter volume; TGCT cis rs9443645 0.901 rs7742431 chr6:79679577 A/G cg05283184 chr6:79620031 NA -0.21 -4.74 -0.39 5.87e-6 Intelligence (multi-trait analysis); TGCT cis rs1577917 0.958 rs1335442 chr6:86466692 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.81e-7 Response to antipsychotic treatment; TGCT cis rs12681288 0.862 rs2600493 chr8:1024970 A/G cg04851639 chr8:1020857 NA -0.4 -7.68 -0.57 4.17e-12 Schizophrenia; TGCT trans rs3808502 0.563 rs12541800 chr8:11423072 A/G cg15556689 chr8:8085844 FLJ10661 0.82 7.48 0.56 1.16e-11 Neuroticism; TGCT cis rs8077577 0.895 rs3088233 chr17:18112675 C/T cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg13695892 chr22:41940480 POLR3H -0.87 -8.01 -0.58 6.94e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs797680 0.964 rs12139009 chr1:93573493 A/G cg17826107 chr1:92977322 EVI5 -0.22 -5.12 -0.42 1.12e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs875971 0.862 rs7782704 chr7:65805366 G/A cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.43e-7 Aortic root size; TGCT cis rs265548 0.538 rs36688 chr19:17911212 A/C cg21960279 chr19:17905606 B3GNT3 0.49 5.73 0.46 7.21e-8 Tumor biomarkers; TGCT cis rs4700695 0.534 rs152999 chr5:65213108 G/T cg21114390 chr5:65439923 SFRS12 0.67 4.67 0.39 7.82e-6 Facial morphology (factor 19); TGCT cis rs2742417 0.609 rs2673066 chr3:45771200 C/T cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9818758 0.607 rs9850917 chr3:49286983 A/G cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9913156 0.793 rs72835643 chr17:4573612 G/A cg00122941 chr17:4613640 ARRB2 0.89 7.52 0.56 9.78e-12 Lymphocyte counts; TGCT cis rs2066819 1.000 rs59811639 chr12:56695954 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs854765 0.693 rs8079321 chr17:17760789 C/T cg09796270 chr17:17721594 SREBF1 0.24 4.8 0.4 4.56e-6 Total body bone mineral density; TGCT cis rs6121246 0.523 rs6060286 chr20:30197663 C/A cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs8077889 0.956 rs4793025 chr17:41841621 T/C cg26893861 chr17:41843967 DUSP3 1.08 13.44 0.77 5.71e-26 Triglycerides; TGCT cis rs568617 0.953 rs1151519 chr11:65645831 G/C cg04055107 chr11:65626734 MUS81;CFL1 -0.57 -5.22 -0.42 7.39e-7 Crohn's disease; TGCT cis rs9611565 0.559 rs132768 chr22:42013523 C/A cg17554472 chr22:41940697 POLR3H 0.5 5.35 0.43 4.07e-7 Vitiligo; TGCT cis rs7819412 0.505 rs67849263 chr8:11007544 G/T cg21775007 chr8:11205619 TDH -0.58 -5.4 -0.44 3.32e-7 Triglycerides; TGCT cis rs8031584 0.706 rs2177670 chr15:31157751 G/T cg14829155 chr15:31115871 NA -0.36 -4.72 -0.39 6.14e-6 Huntington's disease progression; TGCT cis rs6987853 0.933 rs1343875 chr8:42424749 C/T cg20539142 chr8:42623718 CHRNA6 -0.21 -4.97 -0.41 2.13e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs56104184 0.723 rs116909499 chr19:49407733 C/T cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg21724239 chr8:58056113 NA 0.52 5.47 0.44 2.37e-7 Developmental language disorder (linguistic errors); TGCT cis rs6683383 1.000 rs7555556 chr1:203090976 C/T cg04395153 chr1:203052423 MYOG -0.27 -4.58 -0.38 1.12e-5 Asthma; TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg11494091 chr17:61959527 GH2 0.59 14.01 0.78 2.49e-27 Prudent dietary pattern; TGCT cis rs5750830 0.649 rs5757664 chr22:39821536 A/G cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs5417 0.788 rs2654185 chr17:7183362 G/T cg25256661 chr17:7137939 DVL2 0.57 5.6 0.45 1.34e-7 Diastolic blood pressure; TGCT cis rs2050392 0.544 rs598672 chr10:30742388 C/T cg18806716 chr10:30721971 MAP3K8 -0.55 -6.73 -0.52 5.67e-10 Inflammatory bowel disease; TGCT cis rs7666738 0.791 rs7665273 chr4:98997413 C/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.16e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs17001868 0.568 rs2280790 chr22:40745181 T/C cg07138101 chr22:40742427 ADSL 0.74 5.52 0.44 1.92e-7 Mammographic density (dense area); TGCT cis rs12681288 0.676 rs2701914 chr8:999935 C/T cg04851639 chr8:1020857 NA -0.32 -5.32 -0.43 4.74e-7 Schizophrenia; TGCT cis rs6460942 1.000 rs111761262 chr7:12415916 T/C cg06484146 chr7:12443880 VWDE -0.59 -5.64 -0.45 1.1e-7 Coronary artery disease; TGCT cis rs7223966 1.000 rs11871767 chr17:61698723 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.66 0.39 8.03e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg11301795 chr4:187892539 NA -0.33 -5.11 -0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7698623 0.850 rs6813016 chr4:88768808 T/C cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.28e-6 Cardiovascular disease risk factors; TGCT cis rs1008375 1.000 rs4642241 chr4:17617111 T/C cg16339924 chr4:17578868 LAP3 0.61 5.18 0.42 8.84e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2075371 1.000 rs447266 chr7:133989543 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.39e-9 Mean platelet volume; TGCT cis rs36051895 0.623 rs7023639 chr9:5244058 A/C cg02405213 chr9:5042618 JAK2 -0.72 -8.76 -0.62 1.2e-14 Pediatric autoimmune diseases; TGCT cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.56 4.81 0.4 4.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6988636 0.710 rs62521799 chr8:124134987 G/A cg27053337 chr8:124217698 FAM83A 0.79 4.85 0.4 3.65e-6 Urinary uromodulin levels; TGCT cis rs2688608 0.618 rs28718766 chr10:75489844 C/A cg19442545 chr10:75533431 FUT11 -0.37 -5.87 -0.47 3.81e-8 Inflammatory bowel disease; TGCT cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.6e-6 Menopause (age at onset); TGCT cis rs9534288 0.797 rs9534282 chr13:46588944 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs10744422 0.764 rs4038081 chr12:123292922 G/A cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs11676348 0.783 rs4674252 chr2:218984478 G/A cg00012203 chr2:219082015 ARPC2 -0.52 -4.98 -0.41 2.08e-6 Ulcerative colitis; TGCT cis rs8177253 1.000 rs8177248 chr3:133479626 C/T cg16414030 chr3:133502952 NA -0.6 -8.73 -0.62 1.41e-14 Iron status biomarkers; TGCT cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1667284 1.000 rs1667283 chr18:29223621 C/T cg15259973 chr18:29078565 DSG2 0.53 5.17 0.42 9.05e-7 Problematic alcohol use in trauma-exposed individuals; TGCT trans rs57221529 0.766 rs12518859 chr5:587432 C/T cg25482853 chr8:67687455 SGK3 1.2 10.12 0.67 6.42e-18 Lung disease severity in cystic fibrosis; TGCT cis rs838147 0.505 rs1688264 chr19:49209560 T/G cg13540341 chr19:49222985 MAMSTR -0.37 -4.98 -0.41 2.08e-6 Dietary macronutrient intake; TGCT cis rs1421811 0.630 rs72740637 chr5:32710486 G/A cg16267343 chr5:32710456 NPR3 0.83 7.14 0.54 7.02e-11 Blood pressure; TGCT cis rs3026101 0.671 rs739768 chr17:5290703 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.57 0.38 1.16e-5 Body mass index; TGCT cis rs7843479 0.930 rs4871903 chr8:21827833 C/T cg17168535 chr8:21777572 XPO7 -0.62 -5.67 -0.45 9.37e-8 Mean corpuscular volume; TGCT cis rs1215050 0.818 rs1214917 chr4:99080029 G/T cg17366294 chr4:99064904 C4orf37 0.45 4.45 0.37 1.91e-5 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4285028 0.699 rs1344279 chr3:121615679 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.75 -6.01 -0.48 1.89e-8 Multiple sclerosis; TGCT cis rs2046867 0.661 rs9861834 chr3:72909272 C/T cg25664220 chr3:72788482 NA -0.44 -6.07 -0.48 1.47e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7513165 0.867 rs7524621 chr1:204160938 A/G cg04791601 chr1:204159016 NA -0.26 -5.05 -0.41 1.56e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs2458413 0.542 rs2669451 chr8:105371096 C/A cg04554929 chr8:105342491 NA 0.48 5.77 0.46 5.95e-8 Paget's disease; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg23131131 chr22:24373011 LOC391322 0.81 8.92 0.63 4.97e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs2832077 0.527 rs2738953 chr21:30238363 G/C cg14791747 chr16:20752902 THUMPD1 -1.01 -10.54 -0.69 6.23e-19 Cognitive test performance; TGCT cis rs2486012 0.649 rs37464 chr1:44284161 A/G cg12908607 chr1:44402522 ARTN -0.69 -5.2 -0.42 7.81e-7 Intelligence (multi-trait analysis); TGCT cis rs10193935 0.901 rs10174872 chr2:42459807 T/G cg27598129 chr2:42591480 NA -0.39 -5.15 -0.42 9.84e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9467711 0.591 rs34351439 chr6:25833010 T/C cg16898833 chr6:26189333 HIST1H4D 1.21 5.94 0.47 2.64e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs6598955 0.671 rs12116908 chr1:26587918 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs10875746 0.951 rs4760689 chr12:48563644 G/A cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs59698941 0.943 rs17691584 chr5:132284251 A/C cg27099455 chr5:132201840 GDF9;UQCRQ 0.37 4.47 0.37 1.74e-5 Apolipoprotein A-IV levels; TGCT cis rs10540 1.000 rs79808876 chr11:465763 C/A cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs9330316 0.506 rs56288075 chr2:110398506 A/G cg03552103 chr2:110373002 SEPT10;ANKRD57 -0.4 -4.47 -0.37 1.76e-5 Schizophrenia; TGCT cis rs904251 0.600 rs4714068 chr6:37455642 A/C cg01843034 chr6:37503916 NA -0.48 -6.23 -0.49 6.67e-9 Cognitive performance; TGCT cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg11494091 chr17:61959527 GH2 -0.55 -12.26 -0.74 4.12e-23 Prudent dietary pattern; TGCT cis rs35146811 0.735 rs2272344 chr7:99786819 C/T cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs12681287 0.711 rs28420256 chr8:87255599 C/T cg27223183 chr8:87520930 FAM82B -0.8 -5.69 -0.46 8.66e-8 Caudate activity during reward; TGCT cis rs12733856 0.906 rs4399167 chr1:221493176 A/G cg16137147 chr1:221067896 NA 0.42 4.57 0.38 1.14e-5 Mortality in heart failure; TGCT cis rs769267 0.965 rs1010207 chr19:19416045 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs7552404 1.000 rs1498316 chr1:76159198 G/A cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2050392 1.000 rs2265186 chr10:30691743 C/T cg18806716 chr10:30721971 MAP3K8 0.41 4.84 0.4 3.77e-6 Inflammatory bowel disease; TGCT cis rs10883723 0.810 rs6584504 chr10:104253507 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg03060546 chr3:49711283 APEH 0.54 5.13 0.42 1.11e-6 Menarche (age at onset); TGCT cis rs453301 0.658 rs9650616 chr8:8869199 T/G cg15556689 chr8:8085844 FLJ10661 -0.61 -4.98 -0.41 2.09e-6 Joint mobility (Beighton score); TGCT cis rs12497850 1.000 rs12497850 chr3:48748989 G/T cg18654377 chr3:49208889 KLHDC8B -0.44 -6.06 -0.48 1.52e-8 Parkinson's disease; TGCT cis rs1005277 0.579 rs2474574 chr10:38387295 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9911578 0.934 rs58092632 chr17:57111101 T/C cg05425664 chr17:57184151 TRIM37 0.66 6.48 0.5 1.92e-9 Intelligence (multi-trait analysis); TGCT cis rs7826238 0.623 rs2976893 chr8:8338219 G/T cg06636001 chr8:8085503 FLJ10661 -0.6 -5.49 -0.44 2.13e-7 Systolic blood pressure; TGCT cis rs1670533 0.932 rs13140571 chr4:1054358 T/C cg20887711 chr4:1340912 KIAA1530 0.72 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs13082711 0.522 rs586229 chr3:27354520 A/G cg02860705 chr3:27208620 NA 0.33 5.37 0.43 3.67e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs709400 0.663 rs2273703 chr14:103918029 C/G cg12935359 chr14:103987150 CKB -0.35 -5.24 -0.43 6.66e-7 Body mass index; TGCT cis rs2070488 0.699 rs13078966 chr3:38517914 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.77 7.53 0.56 9.03e-12 Electrocardiographic conduction measures; TGCT cis rs910316 1.000 rs1043674 chr14:75549370 T/C cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs12210905 0.920 rs72839469 chr6:27304539 G/A cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs9303401 0.659 rs2072316 chr17:56604813 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs7267979 0.586 rs6050431 chr20:25183908 C/T cg16686733 chr20:25566563 NINL 0.53 5.43 0.44 2.9e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs72768842 0.808 rs72768807 chr5:78933644 G/A cg24834873 chr5:79865402 ANKRD34B -1.16 -4.61 -0.38 9.84e-6 Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs6570726 0.902 rs396681 chr6:145853603 T/C cg23711669 chr6:146136114 FBXO30 0.7 6.88 0.53 2.56e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3096299 0.900 rs4785663 chr16:89434888 G/A cg06640241 chr16:89574553 SPG7 0.66 6.51 0.5 1.71e-9 Multiple myeloma (IgH translocation); TGCT cis rs11711311 1.000 rs11719303 chr3:113494524 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.38 -0.55 2e-11 IgG glycosylation; TGCT cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg11279151 chr3:101281821 RG9MTD1 -0.44 -9.59 -0.65 1.25e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs7824557 0.602 rs7816636 chr8:11205654 T/A cg21775007 chr8:11205619 TDH 0.71 6.7 0.52 6.36e-10 Retinal vascular caliber; TGCT trans rs17685 0.712 rs869805 chr7:75688596 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 8.84 0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs12643440 0.538 rs6818238 chr4:17140193 C/T cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs16975963 0.793 rs11666497 chr19:38464262 C/T cg14550563 chr19:38990264 RYR1 0.28 4.58 0.38 1.09e-5 Longevity; TGCT cis rs3617 0.573 rs9810807 chr3:52924227 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.51 4.97 0.41 2.21e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs137699 0.652 rs137706 chr22:39751400 T/G cg01416388 chr22:39784598 NA -0.59 -4.73 -0.39 6.08e-6 IgG glycosylation; TGCT trans rs916888 0.773 rs199451 chr17:44801784 G/A cg07870213 chr5:140052090 DND1 0.68 8.26 0.6 1.83e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12497850 0.931 rs13064784 chr3:49135961 C/G cg05785598 chr3:49045655 WDR6 0.36 4.77 0.39 5.17e-6 Parkinson's disease; TGCT cis rs317689 0.581 rs160829 chr12:69769538 G/C cg20891283 chr12:69753455 YEATS4 0.65 5.74 0.46 6.91e-8 Response to diuretic therapy; TGCT cis rs4862750 0.832 rs4862744 chr4:187877074 T/A cg10295955 chr4:187884368 NA -0.93 -12.48 -0.75 1.18e-23 Lobe attachment (rater-scored or self-reported); TGCT cis rs7027203 1.000 rs13288708 chr9:96509653 T/C cg14598338 chr9:96623480 NA 0.57 7.82 0.57 1.97e-12 DNA methylation (variation); TGCT cis rs992157 0.560 rs12992937 chr2:219087072 A/T cg00012203 chr2:219082015 ARPC2 -0.81 -9.36 -0.64 4.37e-16 Colorectal cancer; TGCT cis rs4722585 0.533 rs757371 chr7:26199207 A/G cg07876897 chr7:26191696 NFE2L3 0.39 5.25 0.43 6.35e-7 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs763014 0.931 rs2071981 chr16:630025 C/G cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs7226408 0.857 rs72888996 chr18:34580055 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs11578119 0.933 rs10919406 chr1:170419037 C/G cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.66e-8 Male-pattern baldness; TGCT cis rs2013441 1.000 rs2386429 chr17:20210809 G/A cg23224458 chr17:20280056 CCDC144C -0.41 -4.9 -0.4 2.98e-6 Obesity-related traits; TGCT cis rs453301 0.686 rs6987107 chr8:8893581 A/G cg15556689 chr8:8085844 FLJ10661 -0.62 -5.24 -0.43 6.69e-7 Joint mobility (Beighton score); TGCT cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg07507251 chr3:52567010 NT5DC2 0.46 6.66 0.51 7.92e-10 Bipolar disorder; TGCT cis rs2439831 1.000 rs2444029 chr15:43737484 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT trans rs3790455 0.560 rs1171551 chr1:156472214 C/T cg16443977 chr5:115884994 SEMA6A -0.39 -6.86 -0.52 2.94e-10 Migraine; TGCT cis rs7095607 1.000 rs7079481 chr10:69959242 C/A cg18986048 chr10:69913749 MYPN 0.46 5.0 0.41 1.91e-6 Lung function (FVC); TGCT cis rs6570726 0.791 rs6915094 chr6:145883540 C/G cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2760061 0.626 rs596675 chr1:228117892 G/A cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.37e-9 Diastolic blood pressure; TGCT trans rs561341 1.000 rs561341 chr17:30316385 T/G cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs10779751 0.879 rs7543400 chr1:11283964 C/G cg08854313 chr1:11322531 MTOR 0.92 10.06 0.67 9.08e-18 Body mass index; TGCT cis rs922182 0.617 rs11852732 chr15:64239907 G/A cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.35e-10 Blood protein levels; TGCT cis rs12602901 0.528 rs12601694 chr17:4980381 C/T cg20814095 chr17:4802981 CHRNE;C17orf107 -0.51 -4.65 -0.39 8.39e-6 Blood metabolite levels; TGCT trans rs916888 0.610 rs199453 chr17:44800946 C/T cg01341218 chr17:43662625 NA 0.84 7.62 0.56 5.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4689388 0.926 rs3821940 chr4:6286711 C/A cg25554036 chr4:6271136 WFS1 0.57 8.16 0.59 3.18e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3733585 0.699 rs6823361 chr4:9963127 A/G cg11266682 chr4:10021025 SLC2A9 -0.57 -7.47 -0.56 1.23e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2932538 0.922 rs12402469 chr1:113076625 G/A cg22162597 chr1:113214053 CAPZA1 0.28 5.98 0.47 2.26e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs3793917 0.948 rs3750847 chr10:124215421 C/T cg09507567 chr10:124027408 NA 0.38 4.71 0.39 6.62e-6 Age-related macular degeneration; TGCT cis rs9486719 0.948 rs2092095 chr6:96870864 T/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs801193 0.904 rs4718405 chr7:66254646 A/G cg18876405 chr7:65276391 NA 0.39 5.8 0.46 5.07e-8 Aortic root size; TGCT cis rs9916302 0.706 rs4794808 chr17:37531916 C/T cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs7681440 0.933 rs10005233 chr4:90743331 C/T cg20003494 chr4:90757398 SNCA -0.54 -5.04 -0.41 1.59e-6 Dementia with Lewy bodies; TGCT cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg06640241 chr16:89574553 SPG7 0.76 8.5 0.61 5.12e-14 Multiple myeloma (IgH translocation); TGCT cis rs6669072 0.669 rs712031 chr1:91243395 A/G cg08895590 chr1:91227319 NA -0.35 -4.61 -0.38 1e-5 Cognitive function; TGCT cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4665809 1.000 rs750451 chr2:26324241 G/A cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs617219 0.671 rs1316753 chr5:78531337 G/C cg09550809 chr5:78407562 BHMT 0.37 5.25 0.43 6.49e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7647973 1.000 rs1982861 chr3:49577665 A/G cg06212747 chr3:49208901 KLHDC8B 0.54 4.45 0.37 1.87e-5 Menarche (age at onset); TGCT cis rs4563143 0.663 rs10417671 chr19:29235335 T/C cg03161606 chr19:29218774 NA 0.55 5.86 0.47 3.91e-8 Methadone dose in opioid dependence; TGCT cis rs1555895 0.656 rs4881532 chr10:845449 A/G cg02193355 chr10:851439 NA 0.23 4.96 0.41 2.24e-6 Survival in rectal cancer; TGCT cis rs4595586 0.525 rs4450203 chr12:39381493 T/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs317689 0.702 rs544696 chr12:69749939 T/C cg11871910 chr12:69753446 YEATS4 0.62 5.48 0.44 2.3e-7 Response to diuretic therapy; TGCT cis rs7095607 0.560 rs7095238 chr10:69913203 T/C cg18986048 chr10:69913749 MYPN 0.52 5.78 0.46 5.75e-8 Lung function (FVC); TGCT cis rs9911578 0.967 rs8082544 chr17:57185807 C/T cg12560992 chr17:57184187 TRIM37 -0.79 -9.71 -0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT trans rs916888 0.610 rs199454 chr17:44800110 G/A cg10053473 chr17:62856997 LRRC37A3 0.4 6.71 0.52 6.33e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10242455 0.702 rs76702117 chr7:98916779 A/G cg13560068 chr7:99070416 ZNF789 1.1 4.68 0.39 7.38e-6 Blood metabolite levels; TGCT cis rs7715806 0.500 rs4704233 chr5:75000792 G/A cg19683494 chr5:74908142 NA 0.57 5.0 0.41 1.92e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs9914988 0.943 rs9898892 chr17:27150750 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs78456975 0.628 rs13426896 chr2:1554768 C/T cg01028140 chr2:1542097 TPO -0.37 -5.32 -0.43 4.71e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2836974 0.965 rs8134733 chr21:40683459 C/T cg17971929 chr21:40555470 PSMG1 0.98 8.77 0.62 1.16e-14 Cognitive function; TGCT cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg26818010 chr10:134567672 INPP5A -0.35 -4.56 -0.38 1.23e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7826238 0.720 rs12546760 chr8:8374836 A/G cg06636001 chr8:8085503 FLJ10661 -0.75 -6.99 -0.53 1.52e-10 Systolic blood pressure; TGCT cis rs28595532 0.920 rs114210107 chr4:119734491 G/A cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs854765 0.505 rs2955358 chr17:17946623 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.8 -8.44 -0.6 6.83e-14 Total body bone mineral density; TGCT cis rs3820068 0.581 rs59991988 chr1:15950552 T/A cg05660106 chr1:15850417 CASP9 0.86 8.48 0.61 5.53e-14 Systolic blood pressure; TGCT cis rs1008375 1.000 rs2872959 chr4:17677163 G/A cg18681998 chr4:17616180 MED28 -0.86 -8.6 -0.61 2.91e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7769051 1.000 rs9399041 chr6:133096233 T/G cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs1008375 0.931 rs3775926 chr4:17599837 G/A cg18681998 chr4:17616180 MED28 0.96 9.77 0.66 4.67e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg27535305 chr1:53392650 SCP2 -0.27 -5.1 -0.42 1.23e-6 Monocyte count; TGCT cis rs2721195 0.577 rs4532636 chr8:145904423 A/C cg17328964 chr8:145687451 CYHR1 0.44 5.64 0.45 1.1e-7 Age at first birth; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg02953382 chr22:24373134 LOC391322 0.8 6.87 0.53 2.77e-10 S-phenylmercapturic acid levels in smokers; TGCT cis rs61990749 0.597 rs12887282 chr14:78200585 C/A cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs6495122 0.618 rs4886413 chr15:75262310 G/C cg09165964 chr15:75287851 SCAMP5 0.51 4.65 0.39 8.33e-6 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs157350 0.638 rs157333 chr5:156117200 G/C cg19020398 chr5:156886415 NIPAL4 0.3 4.46 0.37 1.84e-5 Anthropometric traits; TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg25151919 chr3:44754333 ZNF502 -0.4 -4.62 -0.38 9.52e-6 Depressive symptoms; TGCT cis rs9906944 0.864 rs9902512 chr17:47094274 C/G cg07075026 chr17:47091521 IGF2BP1 -0.44 -4.81 -0.4 4.23e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs35883536 0.647 rs12043865 chr1:101042651 G/A cg10298815 chr1:101004474 GPR88 -0.25 -4.73 -0.39 6.03e-6 Monocyte count; TGCT cis rs12477438 0.798 rs6740035 chr2:99576578 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs7666738 0.546 rs34621463 chr4:98793357 G/C cg18180107 chr4:99064573 C4orf37 0.52 4.58 0.38 1.13e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs4960423 chr6:8477210 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7914558 0.966 rs10883817 chr10:104755431 C/T cg04362960 chr10:104952993 NT5C2 0.62 5.49 0.44 2.14e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs11935103 0.712 rs1470751 chr4:187296326 C/T cg16785698 chr4:186456103 PDLIM3 0.44 4.47 0.37 1.74e-5 Response to citalopram treatment; TGCT cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg06221963 chr1:154839813 KCNN3 -0.76 -13.06 -0.76 4.81e-25 Prostate cancer; TGCT cis rs2948294 0.588 rs12544596 chr8:8116346 A/T cg06636001 chr8:8085503 FLJ10661 0.8 6.86 0.52 2.97e-10 Red cell distribution width; TGCT cis rs2180341 0.782 rs4897214 chr6:127723625 G/T cg27446573 chr6:127587934 RNF146 0.8 7.08 0.54 9.53e-11 Breast cancer; TGCT cis rs763014 1.000 rs763014 chr16:675680 T/C cg09263875 chr16:632152 PIGQ 0.31 6.91 0.53 2.25e-10 Height; TGCT cis rs7681440 0.904 rs2301134 chr4:90758945 A/G cg20003494 chr4:90757398 SNCA -0.61 -5.78 -0.46 5.59e-8 Dementia with Lewy bodies; TGCT cis rs2836950 0.501 rs62223052 chr21:40708702 A/C cg11890956 chr21:40555474 PSMG1 -0.63 -5.78 -0.46 5.67e-8 Menarche (age at onset); TGCT cis rs9325144 0.647 rs12231313 chr12:39101929 C/T cg26384229 chr12:38710491 ALG10B -0.57 -5.29 -0.43 5.23e-7 Morning vs. evening chronotype; TGCT trans rs1005277 0.540 rs2224248 chr10:38451886 A/G cg27523141 chr10:43048294 ZNF37B 0.74 8.61 0.61 2.7e-14 Extrinsic epigenetic age acceleration; TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs2797160 1.000 rs2211419 chr6:125995533 C/T cg05901451 chr6:126070800 HEY2 0.74 6.57 0.51 1.23e-9 Endometrial cancer; TGCT cis rs1577917 0.958 rs72907388 chr6:86440207 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.81e-7 Response to antipsychotic treatment; TGCT cis rs2447097 1.000 rs2447097 chr17:2278064 A/C cg27406664 chr17:2294951 MNT 0.27 5.57 0.45 1.5e-7 Autism spectrum disorder; TGCT cis rs8180040 0.903 rs7636423 chr3:47309134 C/G cg27129171 chr3:47204927 SETD2 0.71 8.58 0.61 3.22e-14 Colorectal cancer; TGCT cis rs4808199 0.947 rs7250658 chr19:19571100 A/G cg03709012 chr19:19516395 GATAD2A 1.0 7.8 0.57 2.23e-12 Nonalcoholic fatty liver disease; TGCT cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT trans rs9650657 0.538 rs11250093 chr8:10798828 C/T cg15556689 chr8:8085844 FLJ10661 0.81 7.62 0.56 5.61e-12 Neuroticism; TGCT cis rs4936891 0.645 rs896891 chr11:123910740 C/T cg22125253 chr11:123886957 OR10G4 0.21 4.79 0.4 4.59e-6 Male fertility; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg22764044 chr5:178986830 RUFY1 0.53 6.15 0.48 9.81e-9 Lung cancer; TGCT cis rs12681287 0.640 rs61106663 chr8:87477081 G/C cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs453301 0.624 rs2979265 chr8:8858717 G/C cg15556689 chr8:8085844 FLJ10661 0.79 7.07 0.54 1e-10 Joint mobility (Beighton score); TGCT cis rs1218582 0.741 rs11264281 chr1:154867221 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.65 -6.39 -0.5 3.02e-9 Prostate cancer; TGCT cis rs7617773 0.780 rs11710257 chr3:48373214 T/G cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs11792861 0.816 rs72607157 chr9:111748001 T/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.52 4.86 0.4 3.52e-6 Menarche (age at onset); TGCT cis rs10479542 0.721 rs6894113 chr5:178974789 G/C cg00080972 chr5:178986291 RUFY1 0.46 5.57 0.45 1.54e-7 Lung cancer; TGCT cis rs319204 0.837 rs319140 chr5:146306050 G/A cg25021259 chr5:146258546 PPP2R2B 0.37 4.54 0.38 1.31e-5 Schizophrenia; TGCT cis rs10131894 0.529 rs10162358 chr14:75429593 A/G cg08847533 chr14:75593920 NEK9 0.64 5.9 0.47 3.23e-8 Coronary artery disease; TGCT cis rs986417 0.901 rs1956558 chr14:60975956 T/C cg27398547 chr14:60952738 C14orf39 1.44 8.82 0.62 8.61e-15 Gut microbiota (bacterial taxa); TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg03188948 chr7:1209495 NA 0.45 5.77 0.46 6.08e-8 Longevity;Endometriosis; TGCT cis rs6545883 0.811 rs2921718 chr2:61795267 C/A cg15711740 chr2:61764176 XPO1 -0.6 -5.78 -0.46 5.66e-8 Tuberculosis; TGCT cis rs1577917 0.958 rs3857480 chr6:86535149 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs11785400 0.793 rs9297969 chr8:143723237 A/G cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs597539 0.652 rs646586 chr11:68681653 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.79 -7.29 -0.55 3.12e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4654899 0.865 rs3856173 chr1:21114833 C/T cg01072550 chr1:21505969 NA -0.49 -7.97 -0.58 8.62e-13 Superior frontal gyrus grey matter volume; TGCT cis rs11690935 0.959 rs7608403 chr2:172646765 A/C cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs2204008 0.641 rs2387810 chr12:38368875 G/T cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs7044106 0.718 rs1981021 chr9:123388393 T/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.57 0.38 1.14e-5 Hip circumference adjusted for BMI; TGCT cis rs4851254 0.660 rs34714421 chr2:100692175 T/C cg22139774 chr2:100720529 AFF3 -0.45 -4.88 -0.4 3.13e-6 Intelligence (multi-trait analysis); TGCT cis rs2197308 0.606 rs2218397 chr12:38278307 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.72 -0.39 6.19e-6 Morning vs. evening chronotype; TGCT cis rs6121246 0.821 rs6119718 chr20:30331074 A/G cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs616402 0.527 rs11121581 chr1:10577740 A/G cg17425144 chr1:10567563 PEX14 0.56 8.25 0.6 1.93e-13 Breast size; TGCT cis rs2463822 1.000 rs118049526 chr11:62107508 C/T cg06239285 chr11:62104954 ASRGL1 -0.95 -6.56 -0.51 1.33e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs709400 0.663 rs8015918 chr14:103942991 A/G cg12935359 chr14:103987150 CKB -0.36 -5.55 -0.45 1.67e-7 Body mass index; TGCT cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs644799 0.965 rs602512 chr11:95561682 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.76 0.62 1.22e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs524281 0.861 rs7124165 chr11:65901218 C/T cg00563793 chr11:65837595 PACS1 0.55 4.51 0.38 1.46e-5 Electroencephalogram traits; TGCT cis rs11098499 0.754 rs878372 chr4:120238780 A/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs13191362 0.935 rs34347104 chr6:163055716 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.06 8.12 0.59 3.96e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9868809 0.881 rs3821876 chr3:48668394 G/T cg00383909 chr3:49044727 WDR6 0.97 5.08 0.42 1.34e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs1008375 0.966 rs3796813 chr4:17591648 A/G cg16339924 chr4:17578868 LAP3 0.8 6.9 0.53 2.43e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.512 rs77289815 chr8:57995242 A/G cg20607798 chr8:58055168 NA 0.63 4.51 0.38 1.46e-5 Developmental language disorder (linguistic errors); TGCT cis rs6978712 1.000 rs6978712 chr7:127147763 A/G cg01017541 chr7:127776461 NA -0.76 -4.6 -0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs3820068 0.734 rs72645830 chr1:15889910 A/G cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs514406 0.763 rs6685599 chr1:53213172 G/A cg25767906 chr1:53392781 SCP2 0.48 5.36 0.43 3.95e-7 Monocyte count; TGCT cis rs611744 0.647 rs585077 chr8:109245497 C/T cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs7659604 0.540 rs4361412 chr4:122669403 C/T cg19748678 chr4:122722346 EXOSC9 -0.5 -4.95 -0.41 2.37e-6 Type 2 diabetes; TGCT cis rs7940866 0.838 rs12790299 chr11:130803634 A/G cg12179176 chr11:130786555 SNX19 0.58 5.58 0.45 1.42e-7 Schizophrenia; TGCT cis rs6430585 0.583 rs59243420 chr2:136584538 A/T cg07169764 chr2:136633963 MCM6 1.23 11.99 0.73 1.85e-22 Corneal structure; TGCT cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.47 0.56 1.26e-11 Platelet count; TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.73 6.78 0.52 4.37e-10 Prudent dietary pattern; TGCT cis rs9894429 0.646 rs8080391 chr17:79566319 A/T cg21984481 chr17:79567631 NPLOC4 0.26 4.9 0.4 2.91e-6 Eye color traits; TGCT cis rs6921919 0.583 rs6922429 chr6:28381345 T/C cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9467711 0.606 rs9379864 chr6:26372584 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs651907 0.535 rs61396602 chr3:101509046 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs7552404 0.731 rs6699682 chr1:76340123 A/G cg22875332 chr1:76189707 ACADM -0.68 -7.04 -0.53 1.16e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs763121 0.815 rs9306328 chr22:39028913 C/T cg06022373 chr22:39101656 GTPBP1 0.71 6.77 0.52 4.51e-10 Menopause (age at onset); TGCT cis rs13242816 1.000 rs67652573 chr7:116109958 T/C cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs6840360 0.582 rs57585665 chr4:152327017 G/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.68e-9 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs7666738 0.546 rs10026181 chr4:98814118 C/T cg17366294 chr4:99064904 C4orf37 -0.67 -6.06 -0.48 1.52e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3125734 0.660 rs4979780 chr10:63992740 A/C cg09941381 chr10:64027924 RTKN2 -0.37 -5.58 -0.45 1.45e-7 Rheumatoid arthritis; TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg11003573 chr3:44754125 ZNF502 -0.47 -5.39 -0.44 3.4e-7 Depressive symptoms; TGCT cis rs17376456 0.877 rs67066109 chr5:93494101 G/C cg25358565 chr5:93447407 FAM172A 0.97 8.32 0.6 1.34e-13 Diabetic retinopathy; TGCT cis rs1218582 0.710 rs4845685 chr1:154878300 C/A cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs634534 0.622 rs593525 chr11:65727799 T/C cg04055107 chr11:65626734 MUS81;CFL1 0.45 4.47 0.37 1.73e-5 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7806994 1 rs7806994 chr7:56139505 A/T cg20539350 chr7:56437009 NA 0.31 4.59 0.38 1.08e-5 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs6735179 0.565 rs733376 chr2:1751958 C/A cg08534653 chr2:1747700 PXDN 0.54 4.45 0.37 1.92e-5 Response to antipsychotic treatment; TGCT cis rs514406 0.570 rs1332776 chr1:53189816 C/T cg25767906 chr1:53392781 SCP2 -0.42 -4.88 -0.4 3.16e-6 Monocyte count; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg01802117 chr1:53393560 SCP2 -0.47 -5.61 -0.45 1.23e-7 Monocyte count; TGCT cis rs295140 0.681 rs6435048 chr2:201167854 C/T cg04283868 chr2:201171347 SPATS2L 0.6 5.68 0.45 9.27e-8 QT interval; TGCT cis rs8072100 0.935 rs78737171 chr17:45668760 A/T cg08085267 chr17:45401833 C17orf57 0.43 4.63 0.38 9.02e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6688613 0.840 rs6660048 chr1:166954186 C/T cg07049167 chr1:166818506 POGK -0.27 -5.5 -0.44 2.08e-7 Refractive astigmatism; TGCT cis rs1878931 0.507 rs4429296 chr16:3408277 T/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -5.19 -0.42 8.27e-7 Body mass index (adult); TGCT cis rs2535633 0.631 rs2710314 chr3:52969128 T/C cg10802521 chr3:52805072 NEK4 0.6 6.2 0.49 7.52e-9 Body mass index; TGCT cis rs7208859 0.673 rs9907197 chr17:29018263 C/T cg04154034 chr17:28927549 LRRC37B2 0.75 4.47 0.37 1.73e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9905704 0.624 rs11652761 chr17:56986095 C/T cg05425664 chr17:57184151 TRIM37 -0.57 -4.44 -0.37 1.97e-5 Testicular germ cell tumor; TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg01802117 chr1:53393560 SCP2 -0.39 -4.63 -0.38 9.18e-6 Monocyte count; TGCT cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.686 rs857879 chr6:145974043 C/A cg13319975 chr6:146136371 FBXO30 0.5 4.6 0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs73198271 0.765 rs534103 chr8:8634069 A/G cg06671706 chr8:8559999 CLDN23 -0.36 -4.68 -0.39 7.27e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7666738 0.830 rs13106434 chr4:98991651 T/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs56302600 chr4:119770162 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9443645 0.901 rs9361460 chr6:79589467 C/G cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs1997103 0.954 rs10246216 chr7:55390479 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg13695892 chr22:41940480 POLR3H -0.87 -8.24 -0.59 2.06e-13 Vitiligo; TGCT cis rs11578119 0.933 rs72709772 chr1:170470418 C/G cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs4767364 0.645 rs7974383 chr12:112794714 T/G cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.61e-8 Oral cavity and pharyngeal cancer; TGCT cis rs2692947 0.770 rs12471925 chr2:96555522 C/A cg23100626 chr2:96804247 ASTL 0.37 4.47 0.37 1.74e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7666738 0.830 rs4699589 chr4:98973889 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg06481639 chr22:41940642 POLR3H -0.62 -5.74 -0.46 6.82e-8 Vitiligo; TGCT cis rs2204008 0.837 rs12366727 chr12:38365748 A/C cg13010199 chr12:38710504 ALG10B 0.61 4.77 0.39 5.11e-6 Bladder cancer; TGCT trans rs1005277 0.540 rs4934907 chr10:38015230 A/C cg17830980 chr10:43048298 ZNF37B -0.65 -7.34 -0.55 2.4e-11 Extrinsic epigenetic age acceleration; TGCT cis rs8072100 0.676 rs7221345 chr17:45405144 G/A cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.62e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT trans rs7819412 0.805 rs4333549 chr8:10979561 C/G cg15556689 chr8:8085844 FLJ10661 -0.83 -8.24 -0.59 2.08e-13 Triglycerides; TGCT cis rs4568518 0.530 rs10950690 chr7:17981310 C/G cg03009463 chr7:17980271 SNX13 0.55 4.48 0.37 1.71e-5 Measles; TGCT cis rs7707921 0.914 rs4081859 chr5:81466669 G/A cg15871215 chr5:81402204 ATG10 0.28 4.47 0.37 1.75e-5 Breast cancer; TGCT cis rs1050631 1.000 rs2236718 chr18:33705135 G/T cg25426722 chr18:33708991 SLC39A6;ELP2 0.49 4.83 0.4 3.88e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs7647973 0.710 rs7629322 chr3:49621994 C/T cg03060546 chr3:49711283 APEH 0.62 5.21 0.42 7.77e-7 Menarche (age at onset); TGCT cis rs2013441 1.000 rs34644796 chr17:20064128 C/G cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs7731657 0.509 rs6870590 chr5:130249954 A/G cg08523029 chr5:130500466 HINT1 0.57 4.68 0.39 7.39e-6 Fasting plasma glucose; TGCT cis rs933688 1.000 rs61612071 chr5:90741470 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 8.8 0.62 9.68e-15 Smoking behavior; TGCT cis rs1784581 0.569 rs9365357 chr6:162414913 A/G cg17173639 chr6:162384350 PARK2 0.39 6.51 0.5 1.7e-9 Itch intensity from mosquito bite; TGCT cis rs1218582 0.772 rs2174507 chr1:154887949 C/T cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs2153535 0.580 rs9393022 chr6:8466588 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs8013055 0.846 rs8013827 chr14:105970176 C/T cg19700328 chr14:106028568 NA 0.48 5.47 0.44 2.4e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs17376456 0.877 rs28633397 chr5:93447048 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs7570971 0.583 rs1375132 chr2:135954405 A/G cg07169764 chr2:136633963 MCM6 0.62 5.34 0.43 4.25e-7 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs739401 0.572 rs389128 chr11:3083873 G/T cg05729581 chr11:3078854 CARS -0.57 -5.21 -0.42 7.8e-7 Longevity; TGCT cis rs742320 0.756 rs3765263 chr16:840378 A/G cg03433313 chr16:819064 MIR662 -0.5 -6.78 -0.52 4.26e-10 Mean corpuscular volume; TGCT cis rs7312933 0.618 rs7954523 chr12:42681508 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.57 5.4 0.44 3.2e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs78487399 0.808 rs12105399 chr2:43676939 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10894604 0.558 rs7944972 chr11:132651586 A/G cg16639665 chr11:133402497 OPCML 0.45 4.69 0.39 6.99e-6 Waist-hip ratio; TGCT cis rs981844 1.000 rs56232929 chr4:154665700 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs1865760 0.865 rs9467651 chr6:25958257 C/G cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs3749237 0.595 rs885592 chr3:49497883 T/G cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs9534288 0.797 rs9534283 chr13:46589256 C/A cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs6952808 0.609 rs4721190 chr7:1954732 A/G cg22963979 chr7:1858916 MAD1L1 0.34 5.34 0.43 4.35e-7 Bipolar disorder and schizophrenia; TGCT cis rs7043114 0.525 rs10820964 chr9:95041636 G/A cg14631576 chr9:95140430 CENPP -0.28 -4.65 -0.39 8.23e-6 Height; TGCT cis rs589448 0.902 rs315124 chr12:69771727 G/A cg14784868 chr12:69753453 YEATS4 0.9 10.6 0.69 4.47e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs9788682 0.748 rs569207 chr15:78873119 A/G cg24631222 chr15:78858424 CHRNA5 -0.88 -6.52 -0.51 1.61e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Vitiligo; TGCT cis rs12477438 0.765 rs1453564 chr2:99564428 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs11867934 0.577 rs9893676 chr17:17054951 C/G cg26176665 chr17:16994978 MPRIP 0.23 4.45 0.37 1.87e-5 Diabetic retinopathy; TGCT cis rs13242816 1.000 rs34936262 chr7:116160022 G/A cg02799643 chr7:116139180 CAV2 -0.44 -5.54 -0.45 1.74e-7 P wave duration; TGCT cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs9916302 0.707 rs11078903 chr17:37631924 G/A cg15445000 chr17:37608096 MED1 0.31 4.6 0.38 1.01e-5 Glomerular filtration rate (creatinine); TGCT cis rs35934224 0.783 rs7288170 chr22:19864252 C/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.31 -0.43 4.86e-7 Glaucoma (primary open-angle); TGCT cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg04013166 chr16:89971882 TCF25 0.33 4.47 0.37 1.75e-5 Skin colour saturation; TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg24675658 chr1:53192096 ZYG11B -0.7 -8.15 -0.59 3.44e-13 Monocyte count; TGCT cis rs7085104 0.727 rs12773892 chr10:104631177 G/T cg04362960 chr10:104952993 NT5C2 0.89 6.19 0.49 8.04e-9 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs6433895 1.000 rs59395276 chr2:182020696 T/C cg16904960 chr2:182549928 NA 0.34 4.45 0.37 1.87e-5 Lymphocyte counts; TGCT cis rs864537 0.622 rs2949661 chr1:167424924 C/T cg22356347 chr1:167427500 CD247 -0.19 -4.61 -0.38 9.81e-6 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs7552404 1.000 rs12123977 chr1:76209754 A/G cg10523679 chr1:76189770 ACADM -1.05 -7.93 -0.58 1.1e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs79349575 0.783 rs55771415 chr17:46999937 C/T cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg06481639 chr22:41940642 POLR3H 0.71 6.43 0.5 2.56e-9 Vitiligo; TGCT cis rs7666738 0.719 rs35184673 chr4:99050945 T/C cg17366294 chr4:99064904 C4orf37 0.73 5.48 0.44 2.29e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2235642 0.750 rs1894649 chr16:1657284 C/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.63 -0.38 9.27e-6 Coronary artery disease; TGCT cis rs1799949 0.602 rs4600503 chr17:41414324 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs2486288 0.656 rs8039153 chr15:45579813 T/C cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.45 -0.44 2.57e-7 Glomerular filtration rate; TGCT cis rs78545713 0.892 rs11751286 chr6:26241361 C/G cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.66 -4.71 -0.39 6.57e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs10498514 1.000 rs76202452 chr14:65027352 C/G cg25134081 chr14:64931936 AKAP5 1.13 4.63 0.38 9.22e-6 Cognitive performance; TGCT cis rs6882076 0.961 rs58198139 chr5:156399039 C/T cg12943317 chr5:156479607 HAVCR1 -0.3 -5.6 -0.45 1.34e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs910316 1.000 rs4903275 chr14:75512509 C/T cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.97e-11 Height; TGCT cis rs3617 0.573 rs9825230 chr3:52901974 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.86 -0.4 3.52e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs79349575 0.715 rs1058018 chr17:47000251 C/T cg26022315 chr17:47021804 SNF8 0.49 4.95 0.41 2.37e-6 Type 2 diabetes; TGCT cis rs7772486 0.875 rs2814872 chr6:146310234 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.5 0.65 2.02e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs8180040 0.966 rs11705957 chr3:47443262 T/G cg27129171 chr3:47204927 SETD2 -0.64 -7.39 -0.55 1.89e-11 Colorectal cancer; TGCT cis rs2346177 0.542 rs13024414 chr2:46687062 G/A cg26688816 chr2:46740690 ATP6V1E2 -0.42 -4.51 -0.38 1.49e-5 HDL cholesterol; TGCT cis rs9522267 0.624 rs2774433 chr13:112197418 A/C cg10483660 chr13:112241077 NA -0.28 -4.45 -0.37 1.92e-5 Hepatitis; TGCT cis rs7513165 0.935 rs7538055 chr1:204161069 A/G cg12731349 chr1:204159619 KISS1 0.49 5.62 0.45 1.19e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs2137111 0.579 rs116951852 chr15:77721319 A/T cg22256960 chr15:77711686 NA -0.5 -4.75 -0.39 5.55e-6 Anticoagulant levels; TGCT cis rs4268898 0.722 rs10445893 chr2:24407128 A/G cg05570707 chr2:24270316 C2orf44 0.49 4.84 0.4 3.73e-6 Asthma; TGCT cis rs6088590 1.000 rs28542147 chr20:33376323 G/A cg06115741 chr20:33292138 TP53INP2 0.66 5.51 0.44 2.01e-7 Coronary artery disease; TGCT cis rs1857353 1.000 rs12401896 chr1:75907626 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs1577917 0.771 rs2842601 chr6:86330133 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs17345786 0.906 rs12638137 chr3:101150964 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.751 rs12715665 chr3:10021601 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs9926296 0.712 rs447735 chr16:89734349 T/C cg04287289 chr16:89883240 FANCA -0.55 -5.16 -0.42 9.38e-7 Vitiligo; TGCT cis rs2857078 0.720 rs9906669 chr17:42305706 A/G cg13607699 chr17:42295918 UBTF 0.96 10.81 0.7 1.38e-19 Red cell distribution width;Reticulocyte count; TGCT cis rs4788570 0.615 rs10852502 chr16:71652072 C/A cg06353428 chr16:71660113 MARVELD3 1.54 12.75 0.75 2.57e-24 Intelligence (multi-trait analysis); TGCT cis rs57590327 0.645 rs62265395 chr3:81531932 C/T cg07356753 chr3:81810745 GBE1 -0.58 -4.77 -0.39 5.11e-6 Extraversion; TGCT cis rs4319547 1.000 rs7295397 chr12:123116209 C/T cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.42 -0.44 3.02e-7 Body mass index; TGCT cis rs981844 0.740 rs6841173 chr4:154682563 A/G cg14289246 chr4:154710475 SFRP2 -0.95 -8.8 -0.62 9.96e-15 Response to statins (LDL cholesterol change); TGCT cis rs909002 0.849 rs7546297 chr1:32106494 A/G cg11573219 chr1:32083031 HCRTR1 -0.49 -6.44 -0.5 2.36e-9 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13082711 0.911 rs11709954 chr3:27421427 C/T cg02860705 chr3:27208620 NA 0.35 4.82 0.4 4.03e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2013441 0.965 rs2703820 chr17:20121479 G/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs7582180 0.585 rs13031711 chr2:100939433 T/C cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs78456975 0.527 rs72776299 chr2:1570300 G/C cg12573674 chr2:1569213 NA -0.49 -5.3 -0.43 5.06e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9650657 0.584 rs28613656 chr8:10695419 G/A cg16664915 chr8:10907788 XKR6 -0.29 -4.71 -0.39 6.47e-6 Neuroticism; TGCT cis rs10504229 0.817 rs55891651 chr8:58167600 C/T cg24829409 chr8:58192753 C8orf71 -0.51 -4.93 -0.41 2.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.643 rs2278529 chr2:219502132 C/T cg02176678 chr2:219576539 TTLL4 0.43 6.04 0.48 1.69e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs1670533 1.000 rs13134921 chr4:1054177 A/G cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs35146811 0.961 rs35991721 chr7:99728790 G/T cg13334819 chr7:99746414 C7orf59 -0.82 -7.34 -0.55 2.49e-11 Coronary artery disease; TGCT cis rs2303745 0.622 rs1864113 chr19:17393504 G/C cg02221750 chr19:17393354 ANKLE1 -0.48 -6.28 -0.49 5.17e-9 Systemic lupus erythematosus; TGCT cis rs4285028 0.699 rs1920298 chr3:121597888 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.78 -6.72 -0.52 5.95e-10 Multiple sclerosis; TGCT cis rs8141529 0.509 rs5762863 chr22:29253335 A/C cg02153584 chr22:29168773 CCDC117 0.59 4.65 0.39 8.49e-6 Lymphocyte counts; TGCT cis rs1670533 0.932 rs13108207 chr4:1054218 C/T cg20887711 chr4:1340912 KIAA1530 0.57 4.51 0.38 1.47e-5 Recombination rate (females); TGCT cis rs62244186 0.659 rs9311358 chr3:44538748 C/G cg10263370 chr3:44754102 ZNF502 -0.38 -4.44 -0.37 1.99e-5 Depressive symptoms; TGCT cis rs12049351 0.774 rs6662732 chr1:229629245 A/C cg12130225 chr1:229698885 NA -0.39 -4.59 -0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs3858526 0.920 rs11039698 chr11:5950907 C/T cg13902645 chr11:5959945 NA -0.48 -5.0 -0.41 1.95e-6 DNA methylation (variation); TGCT cis rs514406 0.830 rs533935 chr1:53308807 T/C cg16325326 chr1:53192061 ZYG11B 0.7 8.19 0.59 2.73e-13 Monocyte count; TGCT trans rs7618501 1.000 rs7618519 chr3:49772708 A/T cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.960 rs61797339 chr1:76189946 G/T cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs9325144 0.647 rs7487395 chr12:38865660 C/A cg26384229 chr12:38710491 ALG10B -0.59 -5.47 -0.44 2.33e-7 Morning vs. evening chronotype; TGCT cis rs8017423 0.967 rs11159956 chr14:90715890 C/T cg04374321 chr14:90722782 PSMC1 -0.75 -8.2 -0.59 2.53e-13 Mortality in heart failure; TGCT cis rs7659604 0.676 rs4077102 chr4:122699830 A/G cg20573242 chr4:122745356 CCNA2 0.54 4.88 0.4 3.2e-6 Type 2 diabetes; TGCT trans rs12339966 0.653 rs10756228 chr9:11301783 T/C cg07173112 chr1:1114698 TTLL10 -0.34 -6.91 -0.53 2.26e-10 Systolic blood pressure; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg18538332 chr22:24372958 LOC391322 1.02 13.19 0.76 2.24e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg25767906 chr1:53392781 SCP2 0.5 5.71 0.46 7.92e-8 Monocyte count; TGCT cis rs4460629 0.742 rs7366355 chr1:155076734 C/T cg23973274 chr1:155060172 NA -0.26 -4.66 -0.39 8.1e-6 Serum magnesium levels; TGCT cis rs6845621 0.901 rs6834863 chr4:18919159 C/A cg12196642 chr4:18937545 NA -0.25 -4.47 -0.37 1.74e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs1062177 0.756 rs2915815 chr5:151115883 G/C cg12924095 chr5:151150029 G3BP1 -0.35 -4.95 -0.41 2.35e-6 Preschool internalizing problems; TGCT cis rs3733585 0.648 rs28513781 chr4:9959334 G/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg03188948 chr7:1209495 NA 0.65 5.39 0.44 3.36e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs11190604 1.000 rs10883505 chr10:102280772 C/T cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9913156 0.670 rs9894225 chr17:4546559 A/G cg23387401 chr17:4582204 PELP1 -0.3 -4.6 -0.38 1.01e-5 Lymphocyte counts; TGCT cis rs2932538 0.845 rs6682678 chr1:113206920 A/G cg22162597 chr1:113214053 CAPZA1 -0.28 -6.31 -0.49 4.46e-9 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9467773 1.000 rs9295695 chr6:26528250 C/T cg26531700 chr6:26746687 NA -0.5 -4.9 -0.4 2.92e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.791 rs10013680 chr4:99023030 G/C cg17366294 chr4:99064904 C4orf37 0.72 7.04 0.53 1.18e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.542 rs2043979 chr5:93120782 T/A cg25358565 chr5:93447407 FAM172A -0.62 -5.89 -0.47 3.43e-8 Diabetic retinopathy; TGCT cis rs9318086 0.648 rs35449605 chr13:24472582 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.82 8.98 0.63 3.58e-15 Myopia (pathological); TGCT cis rs2204008 0.805 rs2874289 chr12:38258420 G/A cg26384229 chr12:38710491 ALG10B 0.85 7.47 0.56 1.27e-11 Bladder cancer; TGCT cis rs9341808 0.754 rs9343973 chr6:80913216 A/G cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs3748682 0.731 rs9729719 chr1:38298207 G/A cg04496824 chr1:38276835 MTF1 0.21 4.56 0.38 1.2e-5 Hypothyroidism; TGCT cis rs36051895 0.622 rs13440043 chr9:5268264 A/G cg02405213 chr9:5042618 JAK2 -0.61 -7.25 -0.55 3.96e-11 Pediatric autoimmune diseases; TGCT cis rs265548 0.595 rs265543 chr19:17904260 T/G cg16744531 chr19:17905626 B3GNT3 0.41 5.03 0.41 1.69e-6 Tumor biomarkers; TGCT cis rs4285028 0.948 rs2091664 chr3:121684749 T/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg18538332 chr22:24372958 LOC391322 -0.76 -6.18 -0.49 8.62e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6089829 0.926 rs7273917 chr20:61665975 G/A cg08564027 chr20:61660810 NA 0.37 6.53 0.51 1.49e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.39 -4.9 -0.4 2.97e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7264396 0.580 rs7266028 chr20:34477169 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.6e-6 Total cholesterol levels; TGCT trans rs6089829 0.962 rs6122344 chr20:61661738 C/T cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs6988636 0.710 rs62521797 chr8:124134321 A/T cg27053337 chr8:124217698 FAM83A 0.79 4.87 0.4 3.3e-6 Urinary uromodulin levels; TGCT cis rs2594989 0.895 rs2606741 chr3:11392426 G/A cg00170343 chr3:11313890 ATG7 0.67 5.21 0.42 7.68e-7 Circulating chemerin levels; TGCT cis rs6088580 0.634 rs6579165 chr20:32994715 A/G cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg08439880 chr3:133502540 NA -0.28 -5.15 -0.42 9.73e-7 Iron status biomarkers; TGCT cis rs9902453 0.765 rs3102555 chr17:28044101 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.39 0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs10744422 0.764 rs10847749 chr12:123291506 C/T cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs4449834 0.816 rs2875984 chr8:61674555 C/T cg12485212 chr8:61565947 NA 0.59 4.61 0.38 9.88e-6 Sum eosinophil basophil counts; TGCT cis rs2836950 0.509 rs11088466 chr21:40580017 T/A cg11644478 chr21:40555479 PSMG1 -0.52 -4.77 -0.39 4.98e-6 Menarche (age at onset); TGCT cis rs2456568 0.802 rs10765639 chr11:93636194 G/A cg16099599 chr11:93583650 C11orf90 -0.4 -4.98 -0.41 2.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2180341 0.814 rs9385424 chr6:127726796 A/G cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs35883536 1.000 rs2491822 chr1:101115839 T/C cg06223162 chr1:101003688 GPR88 -0.29 -4.79 -0.4 4.61e-6 Monocyte count; TGCT cis rs28374715 0.635 rs112547435 chr15:41648737 C/G cg18705301 chr15:41695430 NDUFAF1 -0.91 -15.14 -0.81 5.81e-30 Ulcerative colitis; TGCT cis rs7647973 1.000 rs1009051 chr3:49521549 G/A cg07636037 chr3:49044803 WDR6 0.64 5.26 0.43 6.12e-7 Menarche (age at onset); TGCT cis rs637571 0.544 rs55704213 chr11:65730002 C/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.63 6.33 0.49 4.02e-9 Eosinophil percentage of white cells; TGCT cis rs804280 0.505 rs804271 chr8:11627214 C/A cg12395012 chr8:11607386 GATA4 -0.18 -4.9 -0.4 2.96e-6 Myopia (pathological); TGCT cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg15691649 chr6:25882328 NA -0.38 -5.03 -0.41 1.65e-6 Blood metabolite levels; TGCT cis rs904251 0.523 rs2797796 chr6:37480886 T/C cg25019722 chr6:37503610 NA -0.53 -8.19 -0.59 2.75e-13 Cognitive performance; TGCT cis rs12580194 0.593 rs7959837 chr12:55734511 G/A cg10672482 chr12:55725839 OR6C3 -0.52 -4.67 -0.39 7.84e-6 Cancer; TGCT cis rs826838 0.935 rs11183940 chr12:38851642 A/G cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs11785693 0.862 rs11786595 chr8:5001621 T/G cg26367366 chr8:4980734 NA 0.56 4.44 0.37 1.95e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs12220238 0.558 rs76330316 chr10:76002291 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.93 0.58 1.11e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs10489202 0.513 rs4657731 chr1:168081255 C/T cg24449463 chr1:168025552 DCAF6 -0.51 -5.22 -0.42 7.23e-7 Schizophrenia; TGCT cis rs2820315 1.000 rs2644107 chr1:201818629 T/C cg12730843 chr1:201915899 LMOD1 -0.27 -4.77 -0.39 4.98e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs875971 1.000 rs6958484 chr7:65599446 G/A cg18876405 chr7:65276391 NA -0.33 -5.02 -0.41 1.72e-6 Aortic root size; TGCT cis rs11874712 1.000 rs9783888 chr18:43651370 G/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.16 0.42 9.44e-7 Migraine - clinic-based; TGCT cis rs4788815 0.513 rs7204967 chr16:71804287 A/G cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Metabolite levels; TGCT cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg22535103 chr8:58192502 C8orf71 -0.38 -4.88 -0.4 3.25e-6 Developmental language disorder (linguistic errors); TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg12419862 chr22:24373484 LOC391322 -0.79 -8.14 -0.59 3.55e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9859260 0.710 rs34906439 chr3:195779706 A/G cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs2067615 0.524 rs4964186 chr12:107080235 C/T cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs12477438 0.520 rs11685759 chr2:99766217 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.28 0.77 1.43e-25 Chronic sinus infection; TGCT cis rs2066819 1.000 rs11575231 chr12:56744445 T/C cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs288326 0.561 rs17265866 chr2:183822374 G/C cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs6121246 0.567 rs2811 chr20:30194248 A/G cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs986417 0.901 rs1015119 chr14:61027510 G/T cg27398547 chr14:60952738 C14orf39 1.36 9.08 0.63 2.05e-15 Gut microbiota (bacterial taxa); TGCT cis rs4478037 1.000 rs4478037 chr3:33160407 G/A cg19404215 chr3:33155277 CRTAP -1.21 -7.41 -0.55 1.7e-11 Major depressive disorder; TGCT cis rs7091068 0.671 rs1223296 chr10:95404621 T/C cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs11031096 0.542 rs11030404 chr11:3980638 T/C cg18678763 chr11:4115507 RRM1 -0.41 -4.97 -0.41 2.16e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg23758822 chr17:41437982 NA 0.72 6.79 0.52 4.04e-10 Menopause (age at onset); TGCT cis rs2439831 1.000 rs2584726 chr15:43715382 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs2455799 0.559 rs7635539 chr3:15922908 A/G cg13420985 chr3:16524424 RFTN1 -0.35 -4.58 -0.38 1.1e-5 Mean platelet volume; TGCT cis rs7681440 0.845 rs6843084 chr4:90766230 T/C cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs3796352 1.000 rs1346719 chr3:53077372 A/G cg07884673 chr3:53033167 SFMBT1 0.57 5.55 0.45 1.68e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4383453 0.539 rs12629585 chr3:123097706 T/A cg04890266 chr3:123102914 ADCY5 -0.5 -8.32 -0.6 1.32e-13 Gestational age at birth (maternal effect); TGCT cis rs8026198 0.929 rs57347762 chr15:42671558 G/A cg02624051 chr15:42371635 PLA2G4D 0.35 4.46 0.37 1.8e-5 Fibrinogen levels; TGCT cis rs1372520 0.873 rs983361 chr4:90761944 T/G cg01966878 chr4:90757139 SNCA -0.29 -4.78 -0.39 4.92e-6 Neuroticism; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg08736216 chr1:53307985 ZYG11A -0.28 -5.83 -0.46 4.44e-8 Monocyte count; TGCT cis rs9467773 1.000 rs1884949 chr6:26568067 G/A cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs6684514 1.000 rs10908500 chr1:156280671 A/T cg20302342 chr1:156215951 PAQR6 0.35 4.65 0.39 8.23e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT trans rs2727020 0.796 rs7131672 chr11:49274421 A/C cg03929089 chr4:120376271 NA 0.68 7.2 0.54 5.2e-11 Coronary artery disease; TGCT cis rs854765 0.663 rs9915248 chr17:17747514 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.7 -6.65 -0.51 8.42e-10 Total body bone mineral density; TGCT cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs7940866 0.804 rs10894287 chr11:130808483 C/T cg12179176 chr11:130786555 SNX19 0.59 5.97 0.47 2.31e-8 Schizophrenia; TGCT cis rs752010 0.530 rs10789401 chr1:42081111 A/G cg06885757 chr1:42089581 HIVEP3 0.3 5.31 0.43 4.86e-7 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs12049351 0.665 rs10799534 chr1:229657213 A/C cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs1497406 0.744 rs4661718 chr1:16505908 C/T cg20430773 chr1:16534157 ARHGEF19 0.51 5.68 0.45 9e-8 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7172809 0.573 rs2137977 chr15:77575505 T/C cg22256960 chr15:77711686 NA -0.47 -4.61 -0.38 9.99e-6 Glucose homeostasis traits; TGCT cis rs9311474 0.607 rs2015971 chr3:52546820 C/T cg07507251 chr3:52567010 NT5DC2 0.46 6.49 0.5 1.81e-9 Electroencephalogram traits; TGCT cis rs7178572 0.598 rs907373 chr15:77844554 T/C cg22256960 chr15:77711686 NA -0.77 -8.79 -0.62 1.03e-14 Type 2 diabetes; TGCT cis rs34172651 0.517 rs12927710 chr16:24790282 A/C cg06028605 chr16:24865363 SLC5A11 0.4 4.45 0.37 1.91e-5 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.681 rs956391 chr15:43617493 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.92 -7.42 -0.55 1.63e-11 Lung cancer in ever smokers; TGCT cis rs13256369 0.851 rs13255061 chr8:8563834 G/A cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs7296418 0.883 rs1727312 chr12:123642220 G/T cg05973401 chr12:123451056 ABCB9 0.54 4.47 0.37 1.71e-5 Platelet count; TGCT cis rs476633 0.691 rs11858115 chr15:41542591 G/A cg18705301 chr15:41695430 NDUFAF1 -0.55 -7.43 -0.56 1.54e-11 Glomerular filtration rate (creatinine); TGCT cis rs7582180 0.614 rs1530031 chr2:101009326 T/C cg14675211 chr2:100938903 LONRF2 0.5 4.82 0.4 4.16e-6 Intelligence (multi-trait analysis); TGCT cis rs881375 0.967 rs1008382 chr9:123681255 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.83e-7 Rheumatoid arthritis; TGCT cis rs2980439 0.818 rs2945249 chr8:8094726 G/A cg08975724 chr8:8085496 FLJ10661 0.58 5.5 0.44 2.11e-7 Neuroticism; TGCT cis rs13217239 0.646 rs12201393 chr6:26975690 C/A cg15659132 chr6:26577336 NA 0.55 5.55 0.45 1.62e-7 Schizophrenia; TGCT cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs7698623 0.717 rs1982624 chr4:88790847 A/G cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs3809566 1.000 rs3809566 chr15:63333724 A/G cg05507819 chr15:63340323 TPM1 0.49 4.6 0.38 1.03e-5 Platelet count; TGCT cis rs2836950 0.565 rs2836934 chr21:40564885 A/C cg11644478 chr21:40555479 PSMG1 -0.52 -4.9 -0.4 2.88e-6 Menarche (age at onset); TGCT cis rs7208859 0.623 rs216434 chr17:28922335 G/C cg13385521 chr17:29058706 SUZ12P 0.86 5.14 0.42 1.05e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs72634258 0.554 rs13306061 chr1:7913445 C/T cg26816564 chr1:7831052 VAMP3 0.64 4.94 0.41 2.46e-6 Inflammatory bowel disease; TGCT cis rs10431058 0.708 rs11212292 chr11:107463936 T/G cg18204760 chr11:107461044 ELMOD1;LOC643923 0.59 5.1 0.42 1.25e-6 Common traits (Other); TGCT cis rs250677 0.958 rs36078 chr5:148430567 G/A cg23229984 chr5:148520753 ABLIM3 0.22 5.03 0.41 1.66e-6 Breast cancer; TGCT cis rs4819052 0.851 rs28676615 chr21:46676576 G/C cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg13665807 chr20:60559372 TAF4 -0.54 -5.47 -0.44 2.39e-7 Body mass index; TGCT cis rs11083475 0.714 rs1471432 chr19:39260282 G/A cg22649124 chr19:39282077 LGALS7B 0.32 4.68 0.39 7.33e-6 Heart rate; TGCT cis rs6089829 0.962 rs6089824 chr20:61659207 A/G cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs6684514 1.000 rs12563631 chr1:156258953 T/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs67311347 1.000 rs4974017 chr3:40473519 C/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs6087990 0.899 rs6058893 chr20:31392777 C/T cg13636640 chr20:31349939 DNMT3B 1.07 15.67 0.82 3.38e-31 Ulcerative colitis; TGCT cis rs6693567 0.545 rs1694386 chr1:150377965 C/G cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs2404602 0.583 rs12908334 chr15:76581592 C/T cg22467129 chr15:76604101 ETFA -0.62 -8.06 -0.59 5.34e-13 Blood metabolite levels; TGCT cis rs921968 0.643 rs10187066 chr2:219514759 A/G cg02176678 chr2:219576539 TTLL4 0.38 5.47 0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs617219 0.710 rs2607142 chr5:78557948 T/C cg23987322 chr5:78407566 BHMT 0.35 4.69 0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs904251 1.000 rs904251 chr6:37451696 G/T cg01843034 chr6:37503916 NA -0.46 -5.44 -0.44 2.72e-7 Cognitive performance; TGCT cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg19774624 chr17:42201019 HDAC5 -0.84 -8.44 -0.6 7.03e-14 Total body bone mineral density; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg20007245 chr22:24372913 LOC391322 0.76 8.02 0.58 6.75e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3796352 0.527 rs11716506 chr3:52944328 C/T cg15956490 chr3:53032818 SFMBT1 0.41 4.57 0.38 1.18e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7552404 0.889 rs2211080 chr1:76243438 G/A cg22875332 chr1:76189707 ACADM 0.67 7.31 0.55 2.86e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.84 0.52 3.14e-10 Electroencephalogram traits; TGCT cis rs9303401 0.614 rs17175663 chr17:57108437 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.82 0.46 4.8e-8 Cognitive test performance; TGCT cis rs67311347 0.544 rs2123998 chr3:40359005 C/G cg17264618 chr3:40429014 ENTPD3 -0.29 -4.57 -0.38 1.15e-5 Renal cell carcinoma; TGCT cis rs986417 1.000 rs4901995 chr14:61090629 C/G cg27398547 chr14:60952738 C14orf39 1.41 8.46 0.6 6.27e-14 Gut microbiota (bacterial taxa); TGCT cis rs7010267 0.570 rs7838083 chr8:120016805 A/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT trans rs7618501 1.000 rs7431106 chr3:49808374 G/A cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs3796352 0.686 rs1560333 chr3:53138254 T/C cg15956490 chr3:53032818 SFMBT1 -0.48 -5.98 -0.47 2.23e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11690935 0.632 rs2292816 chr2:172586714 G/C cg13550731 chr2:172543902 DYNC1I2 0.68 5.97 0.47 2.38e-8 Schizophrenia; TGCT cis rs2274273 0.682 rs7141975 chr14:55542216 G/C cg01923255 chr14:55878535 KIAA0831 0.56 4.57 0.38 1.15e-5 Protein biomarker; TGCT cis rs1865760 1.000 rs6910138 chr6:25904352 C/G cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs7208859 0.524 rs57670615 chr17:29069498 A/G cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9443645 0.901 rs9352686 chr6:79758223 T/G cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs61884328 0.733 rs61897858 chr11:47235263 A/T cg13308137 chr11:47528955 CUGBP1 0.38 4.56 0.38 1.23e-5 Total body bone mineral density (age over 60); TGCT trans rs324780 0.544 rs10862688 chr12:83922912 C/T cg27144766 chr5:150604977 CCDC69 0.24 6.91 0.53 2.27e-10 Vertical cup-disc ratio; TGCT cis rs3008870 0.755 rs2815366 chr1:67499930 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.48 0.61 5.61e-14 Lymphocyte percentage of white cells; TGCT cis rs2046867 0.908 rs62251654 chr3:72816488 C/T cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs17376456 0.542 rs2084916 chr5:93194961 A/T cg25358565 chr5:93447407 FAM172A -0.8 -6.09 -0.48 1.31e-8 Diabetic retinopathy; TGCT cis rs1670533 1.000 rs2290408 chr4:1067267 A/C cg20887711 chr4:1340912 KIAA1530 -0.67 -5.36 -0.43 3.93e-7 Recombination rate (females); TGCT cis rs7914558 1.000 rs11191541 chr10:104824199 A/G cg15744005 chr10:104629667 AS3MT -0.39 -4.84 -0.4 3.81e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9929218 0.551 rs2296408 chr16:68713823 A/C cg01251360 chr16:68772225 CDH1 0.26 4.87 0.4 3.31e-6 Colorectal cancer; TGCT cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg07138768 chr7:917805 C7orf20 0.42 5.07 0.41 1.42e-6 Perceived unattractiveness to mosquitoes; TGCT cis rs11167764 0.945 rs4912619 chr5:141471847 G/A cg23435118 chr5:141488016 NDFIP1 -0.28 -4.64 -0.38 8.69e-6 Crohn's disease; TGCT cis rs55883249 1.000 rs62119423 chr2:9726601 C/T cg23886495 chr2:9695866 ADAM17 0.77 4.69 0.39 7.19e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs40363 0.729 rs6501176 chr16:3522197 A/G cg22508957 chr16:3507546 NAT15 -0.45 -5.3 -0.43 5.12e-7 Tuberculosis; TGCT cis rs68170813 0.617 rs6964395 chr7:107080667 G/C cg02696742 chr7:106810147 HBP1 -0.62 -4.63 -0.38 9.11e-6 Coronary artery disease; TGCT trans rs916888 0.687 rs199456 chr17:44797919 C/T cg01341218 chr17:43662625 NA 1.1 8.86 0.62 6.94e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9926296 0.656 rs7191144 chr16:89823393 C/T cg03388025 chr16:89894329 SPIRE2 0.33 4.87 0.4 3.31e-6 Vitiligo; TGCT cis rs35160687 0.901 rs12478575 chr2:86535314 C/G cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.48e-7 Night sleep phenotypes; TGCT cis rs13191362 1.000 rs34697913 chr6:163000187 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1008375 1.000 rs3933453 chr4:17636319 A/C cg10189774 chr4:17578691 LAP3 0.6 5.2 0.42 7.82e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6429082 0.818 rs696248 chr1:235668511 C/A cg26050004 chr1:235667680 B3GALNT2 0.61 5.45 0.44 2.62e-7 Adiposity; TGCT trans rs877282 0.583 rs10904566 chr10:821662 C/G cg22713356 chr15:30763199 NA 0.89 6.64 0.51 8.63e-10 Uric acid levels; TGCT cis rs2239547 0.657 rs12496077 chr3:52886241 G/A cg10802521 chr3:52805072 NEK4 -0.65 -6.14 -0.48 1.02e-8 Schizophrenia; TGCT cis rs694739 0.628 rs617051 chr11:64133638 C/A cg23796481 chr11:64053134 BAD;GPR137 0.63 6.54 0.51 1.44e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs7914558 1.000 rs10748838 chr10:104943986 T/A cg15744005 chr10:104629667 AS3MT -0.39 -4.73 -0.39 5.91e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10197940 0.662 rs13555 chr2:152333304 C/A cg19508488 chr2:152266495 RIF1 0.74 6.66 0.51 7.77e-10 Lung cancer; TGCT trans rs10953454 1.000 rs35337480 chr7:104488467 A/G cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs7267979 1.000 rs401166 chr20:25446308 C/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs763121 0.853 rs6001204 chr22:39100239 T/C cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT trans rs615632 0.570 rs17734541 chr8:9708433 A/G cg15556689 chr8:8085844 FLJ10661 0.74 7.31 0.55 2.85e-11 Neuroticism; TGCT cis rs2836950 0.565 rs2150413 chr21:40614878 C/T cg17971929 chr21:40555470 PSMG1 -0.52 -4.72 -0.39 6.14e-6 Menarche (age at onset); TGCT cis rs7937890 1.000 rs2970334 chr11:14329355 C/T cg19336497 chr11:14380999 RRAS2 0.31 4.93 0.4 2.59e-6 Mitochondrial DNA levels; TGCT cis rs9905704 0.647 rs6503888 chr17:57028126 T/C cg05425664 chr17:57184151 TRIM37 -0.6 -4.75 -0.39 5.47e-6 Testicular germ cell tumor; TGCT cis rs6570726 0.791 rs6900040 chr6:145893134 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs71435601 0.628 rs492255 chr2:21384272 C/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs4820539 0.966 rs5996470 chr22:23483255 G/A cg21100191 chr22:23484243 RTDR1 0.92 11.25 0.71 1.16e-20 Bone mineral density; TGCT cis rs9394841 0.692 rs9381094 chr6:41800629 T/C cg08135965 chr6:41755394 TOMM6 0.55 5.17 0.42 9.29e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs4285028 0.747 rs7648343 chr3:121426195 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.93 -7.31 -0.55 2.85e-11 Multiple sclerosis; TGCT cis rs2290416 0.688 rs34892354 chr8:144690648 G/C cg16316162 chr8:144660157 NAPRT1 0.68 4.48 0.37 1.71e-5 Attention deficit hyperactivity disorder; TGCT cis rs200810 0.549 rs62422117 chr6:97996459 T/G cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.65 -4.45 -0.37 1.91e-5 Body mass index; TGCT cis rs854765 0.551 rs12600546 chr17:17867614 A/G cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs6121246 0.567 rs6060297 chr20:30198560 A/G cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs2153535 0.562 rs9379211 chr6:8463927 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg26818010 chr10:134567672 INPP5A -0.39 -5.72 -0.46 7.66e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7617773 0.851 rs6775179 chr3:48313418 T/C cg11946769 chr3:48343235 NME6 0.72 6.2 0.49 7.83e-9 Coronary artery disease; TGCT cis rs9926296 0.643 rs12596429 chr16:89841374 T/C cg21285383 chr16:89894308 SPIRE2 0.32 4.55 0.38 1.27e-5 Vitiligo; TGCT cis rs12142240 0.698 rs28578741 chr1:46825176 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg22105103 chr4:187893119 NA 0.34 4.73 0.39 5.91e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg10150615 chr22:24372951 LOC391322 -0.82 -8.88 -0.62 6.32e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6866344 0.697 rs17184344 chr5:178129281 A/G cg03877680 chr5:178157825 ZNF354A 0.72 5.84 0.46 4.2e-8 Neutrophil percentage of white cells; TGCT cis rs1113500 0.580 rs1781058 chr1:108564059 C/G cg22161131 chr1:109420278 GPSM2 0.49 4.45 0.37 1.9e-5 Growth-regulated protein alpha levels; TGCT cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs3099143 1.000 rs3106378 chr15:77110524 A/C cg21673338 chr15:77095150 SCAPER -0.52 -4.97 -0.41 2.15e-6 Recalcitrant atopic dermatitis; TGCT cis rs6977660 0.652 rs12673842 chr7:19747437 T/C cg05791153 chr7:19748676 TWISTNB 1.21 7.93 0.58 1.07e-12 Thyroid stimulating hormone; TGCT cis rs9486719 1.000 rs13207333 chr6:96882254 T/C cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs597539 0.652 rs622082 chr11:68703959 A/G cg06028808 chr11:68637592 NA 0.54 6.94 0.53 1.93e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9325144 0.600 rs2171405 chr12:38741030 G/T cg26384229 chr12:38710491 ALG10B -0.61 -5.58 -0.45 1.43e-7 Morning vs. evening chronotype; TGCT cis rs2677744 0.626 rs868547 chr15:91498760 G/A cg01710897 chr15:91497902 RCCD1 0.34 4.84 0.4 3.83e-6 Attention deficit hyperactivity disorder; TGCT cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.87 -9.24 -0.64 8.59e-16 Menarche (age at onset); TGCT cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg00343986 chr7:65444356 GUSB 0.21 5.14 0.42 1.03e-6 Calcium levels; TGCT cis rs477895 0.653 rs34113693 chr11:63900123 G/T cg04317338 chr11:64019027 PLCB3 0.78 6.46 0.5 2.17e-9 Mean platelet volume; TGCT cis rs5769707 0.967 rs9616327 chr22:50010891 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.62 0.38 9.61e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6663390 0.510 rs12566127 chr1:208070646 C/T cg03990033 chr1:208084030 CD34 0.64 4.46 0.37 1.81e-5 Facial morphology (factor 18); TGCT cis rs875971 0.522 rs709604 chr7:65497434 A/G cg00343986 chr7:65444356 GUSB -0.25 -5.8 -0.46 5.09e-8 Aortic root size; TGCT cis rs7617773 0.817 rs9853804 chr3:48327729 T/C cg11946769 chr3:48343235 NME6 0.74 6.34 0.49 3.97e-9 Coronary artery disease; TGCT cis rs1163251 0.869 rs629735 chr1:120206932 G/T cg19096424 chr1:120255104 PHGDH -0.58 -5.37 -0.43 3.79e-7 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg06896619 chr17:61851486 DDX42;CCDC47 0.48 4.53 0.38 1.37e-5 Prudent dietary pattern; TGCT trans rs208520 1.000 rs208537 chr6:66963544 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.88 -8.21 -0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs2016266 0.859 rs11170506 chr12:53730759 G/T cg16917193 chr12:54089295 NA -0.71 -4.66 -0.39 8.11e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs6087990 0.806 rs4911258 chr20:31369479 G/A cg13636640 chr20:31349939 DNMT3B 1.06 12.99 0.76 6.85e-25 Ulcerative colitis; TGCT cis rs9814567 0.929 rs9815297 chr3:134215052 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -9.28 -0.64 7.11e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11190604 0.767 rs77769532 chr10:102193646 T/C cg23241863 chr10:102295624 HIF1AN 0.65 4.89 0.4 3e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10746514 0.804 rs11122429 chr1:232261532 G/A cg09506761 chr1:232265262 NA -0.47 -4.74 -0.39 5.7e-6 Response to statin therapy; TGCT cis rs3087591 0.960 rs9903754 chr17:29634468 G/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.57 -0.56 7.2e-12 Hip circumference; TGCT cis rs12134245 0.776 rs625525 chr1:91997593 C/T cg02896835 chr1:92012615 NA -0.26 -4.75 -0.39 5.59e-6 Breast cancer; TGCT cis rs7772486 0.686 rs4896828 chr6:145953339 A/C cg23711669 chr6:146136114 FBXO30 0.85 9.48 0.65 2.33e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2013441 0.965 rs2386485 chr17:20095246 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs709400 1.000 rs57218990 chr14:104128007 T/A cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs13191362 1.000 rs4260737 chr6:163137746 T/C cg06582575 chr6:163149167 PACRG;PARK2 1.0 7.73 0.57 3.24e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg11845111 chr2:191398756 TMEM194B 0.37 5.65 0.45 1.03e-7 Pulse pressure; TGCT cis rs35146811 0.735 rs1636975 chr7:99812089 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs6121246 0.909 rs6089071 chr20:30378384 C/G cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7681440 0.904 rs3806789 chr4:90759556 C/T cg26578617 chr4:90757533 SNCA -0.48 -4.95 -0.41 2.35e-6 Dementia with Lewy bodies; TGCT cis rs35160687 0.901 rs13017338 chr2:86501553 T/C cg03171300 chr2:86307199 POLR1A 0.32 5.49 0.44 2.18e-7 Night sleep phenotypes; TGCT cis rs6088580 0.634 rs9789792 chr20:32957709 G/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.9 -0.4 2.97e-6 Glomerular filtration rate (creatinine); TGCT cis rs3741151 1.000 rs79078097 chr11:73049771 G/A cg17517138 chr11:73019481 ARHGEF17 1.18 6.18 0.49 8.29e-9 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs981844 1.000 rs2606325 chr4:154652681 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.56 0.61 3.55e-14 Response to statins (LDL cholesterol change); TGCT cis rs7429990 0.932 rs13085054 chr3:48134137 C/T cg11946769 chr3:48343235 NME6 -0.57 -4.77 -0.39 5.14e-6 Educational attainment (years of education); TGCT cis rs73058052 0.597 rs7249925 chr19:50093572 A/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.93 0.47 2.83e-8 Fibrinogen levels; TGCT cis rs10089 1.000 rs77086350 chr5:127494431 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.4 0.55 1.77e-11 Ileal carcinoids; TGCT cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.56 -5.35 -0.43 4.16e-7 Electroencephalogram traits; TGCT cis rs7586879 0.639 rs6713978 chr2:25120851 T/C cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs11098499 0.874 rs6832670 chr4:120118792 A/G cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs8179 1.000 rs4272 chr7:92236829 C/T cg15732164 chr7:92237376 CDK6 0.34 5.38 0.44 3.56e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs514406 0.825 rs9661082 chr1:53245472 A/T cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg22963979 chr7:1858916 MAD1L1 -0.45 -7.41 -0.55 1.74e-11 Bipolar disorder and schizophrenia; TGCT cis rs250677 0.617 rs166106 chr5:148447061 T/C cg23229984 chr5:148520753 ABLIM3 0.22 4.98 0.41 2.05e-6 Breast cancer; TGCT cis rs4478858 0.684 rs3766289 chr1:31760128 G/A cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT trans rs916888 0.821 rs415430 chr17:44859144 C/T cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1153858 1.000 rs67461176 chr15:45676819 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs875971 0.929 rs10950041 chr7:65973875 T/C cg11764359 chr7:65958608 NA 0.59 5.29 0.43 5.45e-7 Aortic root size; TGCT cis rs904251 0.504 rs1757188 chr6:37483808 A/G cg08126542 chr6:37504118 NA -0.44 -6.47 -0.5 2.04e-9 Cognitive performance; TGCT cis rs6921919 0.525 rs9468360 chr6:28344438 T/G cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.875 rs1331640 chr6:146427250 G/A cg23711669 chr6:146136114 FBXO30 0.91 9.94 0.67 1.79e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6121246 0.609 rs6060843 chr20:30297047 G/C cg18721089 chr20:30220636 NA -0.36 -4.56 -0.38 1.2e-5 Mean corpuscular hemoglobin; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg22764044 chr5:178986830 RUFY1 0.52 6.1 0.48 1.22e-8 Lung cancer; TGCT cis rs9733 0.519 rs11587444 chr1:150722844 A/G cg09365446 chr1:150670422 GOLPH3L 0.32 4.73 0.39 6.05e-6 Tonsillectomy; TGCT cis rs9487051 0.714 rs6903695 chr6:109631422 C/G cg01475377 chr6:109611718 NA 0.31 4.9 0.4 2.88e-6 Reticulocyte fraction of red cells; TGCT cis rs12497850 0.931 rs4974080 chr3:49030828 A/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.43 -0.44 2.85e-7 Parkinson's disease; TGCT cis rs9341808 0.727 rs10943697 chr6:80931506 A/C cg08355045 chr6:80787529 NA 0.31 5.4 0.44 3.2e-7 Sitting height ratio; TGCT cis rs2243480 0.615 rs34363376 chr7:65939536 T/C cg20637647 chr7:64974828 NA 0.91 5.33 0.43 4.55e-7 Diabetic kidney disease; TGCT cis rs1018836 0.923 rs6998150 chr8:91645969 A/C cg16814680 chr8:91681699 NA -0.88 -9.64 -0.65 9.18e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2228479 0.850 rs17233448 chr16:89816424 G/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs514406 0.825 rs3863643 chr1:53224577 C/T cg08859206 chr1:53392774 SCP2 0.4 5.97 0.47 2.38e-8 Monocyte count; TGCT cis rs950169 0.580 rs4603535 chr15:85173872 C/T cg12863693 chr15:85201151 NMB 0.46 5.56 0.45 1.6e-7 Schizophrenia; TGCT cis rs2235642 0.653 rs7197288 chr16:1654753 C/A cg11375102 chr16:1583810 IFT140;TMEM204 -0.27 -4.58 -0.38 1.12e-5 Coronary artery disease; TGCT trans rs1005277 0.579 rs1780137 chr10:38501475 C/G cg17830980 chr10:43048298 ZNF37B -0.81 -10.01 -0.67 1.19e-17 Extrinsic epigenetic age acceleration; TGCT cis rs1915146 0.967 rs7086481 chr10:126844523 A/T cg23000734 chr10:126850823 CTBP2 -0.54 -6.18 -0.49 8.27e-9 Menarche (age at onset); TGCT cis rs9611565 0.649 rs5758434 chr22:42116163 G/A cg17554472 chr22:41940697 POLR3H 0.45 4.84 0.4 3.72e-6 Vitiligo; TGCT cis rs10254284 0.851 rs740123 chr7:28166455 G/C cg23620719 chr7:28220237 JAZF1 -0.54 -4.84 -0.4 3.71e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs7439150 0.954 rs72679194 chr4:155473212 G/T cg22130008 chr4:155548532 NA -0.43 -5.38 -0.44 3.5e-7 Fibrinogen levels; TGCT cis rs10089 0.857 rs7718286 chr5:127459414 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs1008375 0.544 rs7685265 chr4:17568510 C/T cg10189774 chr4:17578691 LAP3 0.59 4.89 0.4 3.03e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6582630 0.537 rs6582500 chr12:38534206 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.18 0.42 8.78e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg17264618 chr3:40429014 ENTPD3 -0.35 -5.17 -0.42 9.04e-7 Renal cell carcinoma; TGCT cis rs4919044 0.808 rs4917898 chr10:94808637 T/A cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs56104184 0.779 rs17206693 chr19:49360252 C/G cg17863274 chr19:49399704 TULP2 -0.46 -5.49 -0.44 2.13e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs8077889 0.672 rs1230400 chr17:41845451 G/A cg26893861 chr17:41843967 DUSP3 -1.16 -21.87 -0.89 2.22e-44 Triglycerides; TGCT cis rs6664467 1 rs6664467 chr1:151738403 G/A cg07092448 chr1:151763213 TDRKH -1.23 -8.17 -0.59 3.01e-13 Carotid plaque burden; TGCT cis rs2243480 1.000 rs160642 chr7:65558373 C/T cg18252515 chr7:66147081 NA -1.1 -7.18 -0.54 5.77e-11 Diabetic kidney disease; TGCT cis rs9560113 1.000 rs4773386 chr13:112180896 C/G cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs2439831 0.867 rs2614811 chr15:43913487 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.15 0.42 9.77e-7 Lung cancer in ever smokers; TGCT cis rs2153535 0.580 rs6912374 chr6:8456423 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs936229 0.690 rs2472300 chr15:75033909 A/G cg10253484 chr15:75165896 SCAMP2 -0.57 -4.85 -0.4 3.63e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs12681287 0.640 rs7460650 chr8:87474085 A/G cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs533581 0.866 rs871756 chr16:88969076 G/C cg16701003 chr16:89028210 CBFA2T3 0.37 4.93 0.4 2.62e-6 Social autistic-like traits; TGCT cis rs7216064 0.861 rs62084252 chr17:65879578 G/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9914544 0.545 rs7222893 chr17:18811702 A/G cg26378065 chr17:18585709 ZNF286B 0.51 4.5 0.37 1.53e-5 Educational attainment (years of education); TGCT cis rs11718455 0.883 rs4682926 chr3:44006170 C/T cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg22168489 chr12:122356033 WDR66 -0.2 -4.71 -0.39 6.64e-6 Mean corpuscular volume; TGCT cis rs28595532 0.844 rs80188901 chr4:119500014 C/T cg11846333 chr4:119757529 SEC24D 0.96 4.75 0.39 5.58e-6 Cannabis dependence symptom count; TGCT cis rs11792861 0.816 rs28361186 chr9:111704064 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 5.0 0.41 1.88e-6 Menarche (age at onset); TGCT cis rs1372520 0.873 rs983361 chr4:90761944 T/G cg15133208 chr4:90757351 SNCA -0.46 -5.59 -0.45 1.39e-7 Neuroticism; TGCT cis rs5750830 0.594 rs5757650 chr22:39778419 A/G cg02038168 chr22:39784481 NA -0.67 -6.03 -0.48 1.78e-8 Intelligence (multi-trait analysis); TGCT cis rs3015497 0.616 rs1494181 chr14:51056600 C/T cg04730355 chr14:51134070 SAV1 -0.64 -6.26 -0.49 5.77e-9 Mean platelet volume; TGCT cis rs16866061 1.000 rs11681451 chr2:225334104 T/C cg12698349 chr2:225449008 CUL3 0.96 9.4 0.65 3.52e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Intelligence (multi-trait analysis); TGCT cis rs13631 1.000 rs13631 chr9:140006202 G/A cg14289826 chr9:140003911 NA 0.29 6.47 0.5 2.02e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs6952808 0.609 rs12699453 chr7:1953056 C/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.51 -0.38 1.5e-5 Bipolar disorder and schizophrenia; TGCT cis rs6700896 0.522 rs17127905 chr1:66157125 T/C cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2996428 0.667 rs72640928 chr1:3768568 T/C cg17848003 chr1:3704513 LRRC47 0.18 5.15 0.42 9.99e-7 Red cell distribution width; TGCT cis rs6750047 0.647 rs62136320 chr2:38275953 T/G cg07380506 chr2:38303506 CYP1B1 0.62 5.7 0.46 8.25e-8 Cutaneous malignant melanoma;Melanoma; TGCT cis rs5771225 0.544 rs909688 chr22:50689030 A/G cg16473166 chr22:50639996 SELO 0.7 5.73 0.46 7.2e-8 Late-onset Alzheimer's disease; TGCT cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg11890956 chr21:40555474 PSMG1 1.1 12.28 0.74 3.66e-23 Cognitive function; TGCT cis rs6095298 0.595 rs1885287 chr20:47435117 C/T cg12307787 chr20:48099359 KCNB1 0.43 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.694 rs5758389 chr22:41941749 T/C cg06634786 chr22:41940651 POLR3H -0.81 -8.07 -0.59 5.26e-13 Vitiligo; TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg23273947 chr15:68267131 NA 0.27 7.22 0.54 4.67e-11 Phosphorus levels; TGCT cis rs7100689 0.646 rs2039757 chr10:82078868 C/A cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs6992820 1.000 rs6992820 chr8:56764456 A/G cg06880721 chr8:56792545 LYN -0.66 -5.54 -0.45 1.69e-7 Mean platelet volume; TGCT cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 8.79 0.62 1.01e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs250677 0.687 rs2963485 chr5:148452043 A/G cg23229984 chr5:148520753 ABLIM3 -0.2 -4.68 -0.39 7.4e-6 Breast cancer; TGCT cis rs9926296 0.744 rs154657 chr16:89708096 A/G cg27121462 chr16:89883253 FANCA 0.49 4.58 0.38 1.11e-5 Vitiligo; TGCT cis rs13223928 0.621 rs4722438 chr7:3155813 A/G cg19214707 chr7:3157722 NA 0.47 7.21 0.54 4.73e-11 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs3008870 0.755 rs2815363 chr1:67497221 A/G cg11518657 chr1:67396239 MIER1 -0.47 -4.61 -0.38 9.68e-6 Lymphocyte percentage of white cells; TGCT cis rs11992186 0.505 rs7845203 chr8:8145440 A/G cg15556689 chr8:8085844 FLJ10661 0.67 5.9 0.47 3.27e-8 Neuroticism; TGCT cis rs6918586 0.681 rs198831 chr6:26116996 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.71 -6.76 -0.52 4.93e-10 Schizophrenia; TGCT trans rs6089829 0.816 rs6062397 chr20:61668268 A/G cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs2180341 0.781 rs6913350 chr6:127570560 C/T cg24812749 chr6:127587940 RNF146 0.79 6.6 0.51 1.09e-9 Breast cancer; TGCT cis rs6547741 0.844 rs9941696 chr2:27920064 C/T cg27432699 chr2:27873401 GPN1 -0.24 -6.05 -0.48 1.57e-8 Oral cavity cancer; TGCT cis rs6426558 0.537 rs4500279 chr1:227484482 G/A cg10327440 chr1:227177885 CDC42BPA 0.58 6.88 0.53 2.6e-10 Neutrophil percentage of white cells; TGCT cis rs7829975 0.742 rs1533059 chr8:8684953 A/G cg06636001 chr8:8085503 FLJ10661 -0.7 -6.51 -0.5 1.69e-9 Mood instability; TGCT cis rs6815814 0.768 rs6835514 chr4:38894380 C/T cg02016764 chr4:38805732 TLR1 0.25 4.47 0.37 1.71e-5 Breast cancer; TGCT cis rs8192284 0.965 rs4129267 chr1:154426264 C/T cg00791854 chr1:154392070 IL6R 0.29 4.63 0.38 9.04e-6 Fibrinogen;C-reactive protein;Fibrinogen levels; TGCT cis rs453301 0.686 rs1045527 chr8:8890041 A/G cg00184457 chr8:8946301 NA -0.26 -4.96 -0.41 2.22e-6 Joint mobility (Beighton score); TGCT cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg06634786 chr22:41940651 POLR3H 0.87 8.2 0.59 2.56e-13 Vitiligo; TGCT cis rs259282 0.583 rs3760938 chr19:33106907 C/T cg26639809 chr19:33781782 NA 0.25 5.04 0.41 1.6e-6 Schizophrenia; TGCT cis rs9814567 0.806 rs1880374 chr3:134322113 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs910316 1.000 rs13099 chr14:75599155 G/A cg08847533 chr14:75593920 NEK9 -0.91 -9.69 -0.66 7.1e-17 Height; TGCT trans rs941408 1.000 rs1736183 chr19:2809672 A/G cg22153745 chr1:153894579 GATAD2B -0.63 -7.23 -0.54 4.25e-11 Total cholesterol levels; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg01802117 chr1:53393560 SCP2 -0.39 -4.55 -0.38 1.27e-5 Monocyte count; TGCT trans rs10802346 0.514 rs4443861 chr1:246372574 G/T cg13514129 chr1:39547527 MACF1 0.83 7.37 0.55 2.06e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg15659132 chr6:26577336 NA 0.86 10.81 0.7 1.36e-19 Intelligence (multi-trait analysis); TGCT cis rs9308731 0.966 rs3827536 chr2:111920741 G/T cg04202892 chr2:111875749 ACOXL 0.43 4.6 0.38 1.04e-5 Chronic lymphocytic leukemia; TGCT cis rs2639990 1.000 rs632157 chr18:72911548 G/A cg02750262 chr18:72916776 ZADH2 0.88 6.43 0.5 2.49e-9 Vascular endothelial growth factor levels; TGCT cis rs739496 0.947 rs2285520 chr12:111867487 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs11614913 0.509 rs12300425 chr12:54395082 G/T cg03037150 chr12:54402717 HOXC8 -0.59 -5.19 -0.42 8.4e-7 Waist circumference adjusted for body mass index; TGCT cis rs9972944 0.657 rs9904302 chr17:63758238 A/G cg07283582 chr17:63770753 CCDC46 -0.24 -4.84 -0.4 3.72e-6 Total body bone mineral density; TGCT cis rs3772130 0.923 rs4298081 chr3:121526037 T/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs4975709 0.758 rs4975756 chr5:1882443 T/C cg14773178 chr5:1868261 NA 0.35 4.73 0.39 6.08e-6 Cardiovascular disease risk factors; TGCT cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg10802521 chr3:52805072 NEK4 -0.75 -9.32 -0.64 5.72e-16 Bipolar disorder; TGCT cis rs478607 0.831 rs59739006 chr11:64415903 C/T cg19395706 chr11:64412079 NRXN2 0.48 4.84 0.4 3.8e-6 Urate levels; TGCT cis rs1975974 1.000 rs7224508 chr17:21722352 T/A cg18423549 chr17:21743878 NA -0.55 -5.25 -0.43 6.52e-7 Psoriasis; TGCT cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg07061783 chr6:25882402 NA -0.42 -4.51 -0.38 1.51e-5 Blood metabolite levels; TGCT trans rs916888 0.773 rs199443 chr17:44819565 C/T cg22433210 chr17:43662623 NA 1.04 7.37 0.55 2.07e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg06753367 chr22:24256600 NA -0.25 -4.73 -0.39 5.98e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6429082 0.818 rs291344 chr1:235663860 C/G cg26050004 chr1:235667680 B3GALNT2 -0.56 -4.97 -0.41 2.19e-6 Adiposity; TGCT cis rs6912958 0.559 rs373646 chr6:88056896 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.69 7.07 0.54 1.02e-10 Monocyte percentage of white cells; TGCT trans rs916888 0.773 rs199535 chr17:44822662 A/G cg07870213 chr5:140052090 DND1 0.63 7.6 0.56 6.35e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs77972916 0.519 rs13411327 chr2:43515483 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.96 -0.41 2.23e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs10045504 0.502 rs17352751 chr5:38737836 G/A cg15396434 chr5:38725168 NA -0.35 -4.47 -0.37 1.78e-5 Night sleep phenotypes; TGCT cis rs7681440 0.904 rs6817001 chr4:90766019 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs801193 0.548 rs2109297 chr7:66122384 G/A cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs10504229 0.681 rs11779172 chr8:58045538 A/G cg11062466 chr8:58055876 NA 0.34 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs3733585 0.624 rs58130873 chr4:9972081 T/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.85 -0.58 1.63e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6840360 0.571 rs4696102 chr4:152529658 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs2180341 1.000 rs2326567 chr6:127606160 G/A cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs7412746 0.658 rs57818453 chr1:150763139 G/A cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs7635838 0.892 rs4684773 chr3:11418508 C/T cg00170343 chr3:11313890 ATG7 0.63 5.92 0.47 2.98e-8 HDL cholesterol; TGCT cis rs28489187 0.505 rs7525786 chr1:85884076 C/T cg16011679 chr1:85725395 C1orf52 -0.51 -4.66 -0.39 7.9e-6 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs6701037 0.566 rs13373754 chr1:175139275 C/A cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs9905704 0.647 rs9901655 chr17:56987142 G/A cg05425664 chr17:57184151 TRIM37 -0.57 -4.44 -0.37 1.97e-5 Testicular germ cell tumor; TGCT cis rs13191362 0.935 rs34709632 chr6:163048380 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.89 6.39 0.5 3.1e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs77861329 1.000 rs9843852 chr3:52132029 C/G cg08692210 chr3:52188851 WDR51A 0.86 4.46 0.37 1.79e-5 Macrophage inflammatory protein 1b levels; TGCT cis rs644799 0.965 rs502521 chr11:95533557 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs644799 1.000 rs7749 chr11:95565789 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.88 9.59 0.65 1.24e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4689388 0.889 rs10026334 chr4:6294607 G/A cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7829975 0.564 rs2921060 chr8:8317817 G/T cg08975724 chr8:8085496 FLJ10661 -0.57 -5.49 -0.44 2.14e-7 Mood instability; TGCT cis rs1420338 0.933 rs6462533 chr7:34168028 G/A cg01275685 chr7:34179230 BMPER -0.25 -4.57 -0.38 1.16e-5 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2197308 0.585 rs10878014 chr12:38114496 A/G cg26384229 chr12:38710491 ALG10B 0.58 5.09 0.42 1.28e-6 Morning vs. evening chronotype; TGCT cis rs35306767 0.855 rs55708963 chr10:925712 C/A cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs6748734 1.000 rs4675874 chr2:241819796 A/G cg04034577 chr2:241836375 C2orf54 0.39 6.23 0.49 6.66e-9 Urinary metabolites; TGCT cis rs11105298 1.000 rs11105298 chr12:89876143 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 0.71 5.25 0.43 6.38e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9549367 0.789 rs3764125 chr13:113897648 A/G cg18105134 chr13:113819100 PROZ 0.31 5.13 0.42 1.08e-6 Platelet distribution width; TGCT cis rs1048238 0.506 rs848210 chr1:16259813 A/G cg22431228 chr1:16359049 CLCNKA 0.23 4.51 0.38 1.46e-5 Systolic blood pressure; TGCT cis rs9796 0.717 rs476633 chr15:41392134 C/G cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.76 -0.52 4.79e-10 Menopause (age at onset); TGCT cis rs7216169 1 rs7216169 chr17:5219511 C/T cg21654974 chr17:5389607 DERL2;MIS12 1.08 6.01 0.47 1.95e-8 Red blood cell density in sickle cell anemia; TGCT cis rs10131894 0.508 rs175006 chr14:75445499 C/G cg08847533 chr14:75593920 NEK9 -0.74 -6.04 -0.48 1.66e-8 Coronary artery disease; TGCT cis rs6831352 0.918 rs17218602 chr4:100061073 A/G cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs7208859 0.673 rs36056619 chr17:29172284 T/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9467711 0.606 rs9379856 chr6:26366836 A/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6089829 0.855 rs6062781 chr20:61667128 G/A cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs478304 0.593 rs2236682 chr11:65480090 G/T cg27068330 chr11:65405492 SIPA1 -0.96 -9.18 -0.64 1.19e-15 Acne (severe); TGCT cis rs853679 0.517 rs67878650 chr6:28142587 G/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7267979 0.744 rs6050464 chr20:25209299 C/A cg14121845 chr20:25566513 NINL 0.48 4.96 0.41 2.31e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9487051 0.714 rs9386797 chr6:109632520 C/A cg01475377 chr6:109611718 NA -0.31 -4.73 -0.39 6.12e-6 Reticulocyte fraction of red cells; TGCT cis rs6500602 0.647 rs3747600 chr16:4586222 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.29 5.49 0.44 2.18e-7 Schizophrenia; TGCT cis rs9325144 0.600 rs10748442 chr12:38732939 A/T cg26384229 chr12:38710491 ALG10B 0.61 5.65 0.45 1.05e-7 Morning vs. evening chronotype; TGCT cis rs611744 0.870 rs640068 chr8:109158002 A/G cg21045802 chr8:109455806 TTC35 0.55 4.8 0.4 4.57e-6 Dupuytren's disease; TGCT cis rs7772486 0.790 rs9376968 chr6:146180364 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.47 -0.37 1.74e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9457247 1.000 rs365189 chr6:167384545 G/A cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs1023500 0.573 rs133380 chr22:42468910 C/T cg15557168 chr22:42548783 NA -0.23 -5.85 -0.46 4.16e-8 Schizophrenia; TGCT cis rs2463822 1.000 rs951677 chr11:62107249 G/C cg23876832 chr11:62092739 NA 0.65 4.56 0.38 1.19e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs12477438 0.871 rs13396584 chr2:99611768 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.78 6.6 0.51 1.09e-9 Chronic sinus infection; TGCT cis rs1577917 1.000 rs12203493 chr6:86758642 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.2 -0.42 8.12e-7 Response to antipsychotic treatment; TGCT cis rs10488031 0.850 rs6955605 chr7:37109868 C/A cg06458904 chr7:36312573 EEPD1 0.54 4.62 0.38 9.64e-6 QT interval; TGCT cis rs9467773 1.000 rs2255070 chr6:26501777 C/G cg09904177 chr6:26538194 HMGN4 0.62 6.14 0.48 1.01e-8 Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs67652573 chr7:116109958 T/C cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs2637266 0.703 rs2920792 chr10:78532842 A/T cg18941641 chr10:78392320 NA -0.4 -4.77 -0.39 5.1e-6 Pulmonary function; TGCT cis rs769267 0.930 rs7256149 chr19:19566255 T/C cg08509172 chr19:19383838 TM6SF2 -0.35 -4.6 -0.38 1.02e-5 Tonsillectomy; TGCT cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7178572 0.568 rs1191196 chr15:77646504 C/T cg22256960 chr15:77711686 NA 0.85 8.73 0.62 1.4e-14 Type 2 diabetes; TGCT cis rs9916302 0.660 rs665413 chr17:37455678 T/A cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs1903068 0.853 rs9312657 chr4:56003502 G/A cg01777861 chr4:56023843 NA 0.53 6.21 0.49 7.2e-9 Endometriosis; TGCT cis rs526231 0.784 rs28157 chr5:102595837 G/T cg05225461 chr5:102596755 C5orf30 0.23 4.68 0.39 7.29e-6 Primary biliary cholangitis; TGCT cis rs2067615 0.579 rs10861657 chr12:107131314 A/G cg15890332 chr12:107067104 RFX4 0.3 5.93 0.47 2.85e-8 Heart rate; TGCT cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg06634786 chr22:41940651 POLR3H -0.86 -8.34 -0.6 1.18e-13 Vitiligo; TGCT cis rs12579753 1.000 rs12366580 chr12:82222784 G/A cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs13424612 1.000 rs13424612 chr2:240900121 C/T cg26363272 chr2:240904871 NDUFA10 0.3 5.13 0.42 1.07e-6 Odorant perception (isobutyraldehyde); TGCT cis rs6543140 0.964 rs1523206 chr2:103070175 A/T cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs72781680 0.898 rs72780121 chr2:23995918 T/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs1801251 1.000 rs283480 chr2:233648742 G/A cg08000102 chr2:233561755 GIGYF2 0.63 6.35 0.5 3.67e-9 Coronary artery disease; TGCT cis rs9436747 0.641 rs12028951 chr1:66053081 A/G cg14976592 chr1:65886160 LEPROT;LEPR -0.59 -5.12 -0.42 1.14e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs2439831 0.867 rs2245715 chr15:43818052 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.49 0.44 2.21e-7 Lung cancer in ever smokers; TGCT cis rs317689 0.690 rs10878947 chr12:69642683 A/T cg14784868 chr12:69753453 YEATS4 0.54 4.5 0.37 1.56e-5 Response to diuretic therapy; TGCT cis rs950169 0.922 rs11635505 chr15:85097034 A/C cg12863693 chr15:85201151 NMB -0.4 -4.56 -0.38 1.21e-5 Schizophrenia; TGCT cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg13607699 chr17:42295918 UBTF 0.84 7.55 0.56 8.34e-12 Total body bone mineral density; TGCT cis rs832540 0.898 rs702680 chr5:56220382 T/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.19 -0.42 8.26e-7 Coronary artery disease; TGCT cis rs6695640 0.819 rs2800697 chr1:17731751 C/T cg25979543 chr1:17888104 ARHGEF10L -0.25 -4.57 -0.38 1.14e-5 Mean platelet volume; TGCT cis rs1552244 1.000 rs67569278 chr3:10149893 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.32 -0.49 4.28e-9 Alzheimer's disease; TGCT cis rs13191362 0.938 rs35395472 chr6:163008493 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6840360 0.642 rs2709817 chr4:152382050 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.595 rs6907924 chr6:26438817 T/G cg15659132 chr6:26577336 NA -0.43 -4.51 -0.38 1.47e-5 Intelligence (multi-trait analysis); TGCT cis rs4654899 0.865 rs4654891 chr1:21286391 T/C cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs11031096 0.621 rs12282967 chr11:4191477 A/T cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg13944838 chr5:179740914 GFPT2 -0.38 -5.87 -0.47 3.7e-8 Height; TGCT cis rs7044106 0.791 rs4837793 chr9:123483621 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.47 5.04 0.41 1.59e-6 Hip circumference adjusted for BMI; TGCT cis rs4700695 1.000 rs111340 chr5:65420285 C/A cg21114390 chr5:65439923 SFRS12 -0.65 -5.02 -0.41 1.76e-6 Facial morphology (factor 19); TGCT cis rs11644362 0.966 rs1433746 chr16:12992204 T/C cg06890432 chr16:12997467 SHISA9 -0.6 -6.35 -0.5 3.77e-9 Positive affect;Subjective well-being; TGCT cis rs208520 0.690 rs7739253 chr6:66861052 A/G cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs4722585 0.605 rs10268883 chr7:26200417 C/T cg07876897 chr7:26191696 NFE2L3 0.41 5.52 0.44 1.93e-7 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs2180341 1.000 rs7453272 chr6:127633959 C/T cg27446573 chr6:127587934 RNF146 -1.17 -9.4 -0.65 3.58e-16 Breast cancer; TGCT cis rs875971 0.789 rs10260426 chr7:65736042 G/T cg11764359 chr7:65958608 NA -0.54 -4.86 -0.4 3.45e-6 Aortic root size; TGCT cis rs3820068 0.705 rs4646091 chr1:15822043 T/C cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs611744 0.934 rs672591 chr8:109192453 T/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs8038465 0.516 rs8037836 chr15:73859855 G/A cg15420318 chr15:73925796 NPTN 0.72 7.87 0.58 1.52e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6089584 0.888 rs6587283 chr20:60613727 A/C cg16423285 chr20:60520624 NA -0.61 -6.46 -0.5 2.12e-9 Body mass index; TGCT trans rs4332037 0.707 rs56070303 chr7:1891015 C/T cg10840412 chr1:235813424 GNG4 0.86 6.67 0.51 7.59e-10 Bipolar disorder; TGCT cis rs9486719 0.948 rs2472904 chr6:96874962 T/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg08048268 chr3:133502702 NA -0.52 -6.78 -0.52 4.26e-10 Iron status biomarkers; TGCT cis rs7089973 0.872 rs7918253 chr10:116614501 T/C cg03647239 chr10:116582469 FAM160B1 0.52 4.66 0.39 8.03e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs1536827 0.541 rs11592589 chr10:135363657 G/A cg12448312 chr10:135032219 KNDC1 -0.53 -5.09 -0.42 1.27e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1577917 0.771 rs9362239 chr6:86429263 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.59 5.07 0.41 1.42e-6 Response to antipsychotic treatment; TGCT cis rs35146811 0.700 rs858513 chr7:99825558 G/A cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs10791097 0.568 rs4411284 chr11:130738568 A/C cg14779329 chr11:130786720 SNX19 0.28 4.81 0.4 4.36e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11105298 0.891 rs1008764 chr12:89887649 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs13242816 1.000 rs2402079 chr7:116128670 T/A cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs4253772 0.591 rs6007747 chr22:46657261 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.55 4.46 0.37 1.84e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs4285028 0.747 rs11923248 chr3:121566498 G/T cg01951420 chr3:121553821 IQCB1;EAF2 -1.02 -8.14 -0.59 3.63e-13 Multiple sclerosis; TGCT cis rs4918072 0.716 rs2902638 chr10:105636989 T/C cg11005552 chr10:105648138 OBFC1 0.4 5.13 0.42 1.07e-6 Coronary artery disease; TGCT cis rs12580194 0.556 rs58780687 chr12:55736498 A/C cg10672482 chr12:55725839 OR6C3 -0.51 -4.46 -0.37 1.79e-5 Cancer; TGCT cis rs7552404 0.696 rs10782602 chr1:76464261 T/C cg22875332 chr1:76189707 ACADM 0.66 6.2 0.49 7.69e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg14827481 chr10:134361889 INPP5A 0.3 4.82 0.4 4.18e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg08736216 chr1:53307985 ZYG11A -0.3 -6.07 -0.48 1.45e-8 Monocyte count; TGCT cis rs62380364 0.727 rs216057 chr5:88170331 T/C cg22951263 chr5:87985283 NA 0.5 5.02 0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs12477438 1.000 rs995617 chr2:99857904 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.76 5.63 0.45 1.13e-7 Chronic sinus infection; TGCT cis rs9291683 0.588 rs12507330 chr4:10002195 G/A cg11266682 chr4:10021025 SLC2A9 0.68 9.45 0.65 2.76e-16 Bone mineral density; TGCT cis rs17253792 0.822 rs112374071 chr14:56061919 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1372520 0.873 rs2736989 chr4:90776257 T/C cg20003494 chr4:90757398 SNCA -0.61 -4.88 -0.4 3.15e-6 Neuroticism; TGCT cis rs3812831 0.695 rs6560935 chr13:114945867 G/A cg06611532 chr13:114900021 NA 0.35 6.4 0.5 2.93e-9 Schizophrenia; TGCT cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.69 0.39 7.04e-6 Bipolar disorder; TGCT cis rs7829975 0.711 rs1039916 chr8:8685854 A/G cg15556689 chr8:8085844 FLJ10661 0.68 6.05 0.48 1.55e-8 Mood instability; TGCT cis rs7106204 0.748 rs4360697 chr11:24217160 A/G ch.11.24196551F chr11:24239977 NA 0.46 4.69 0.39 7.23e-6 Response to Homoharringtonine (cytotoxicity); TGCT cis rs6089584 0.924 rs6142906 chr20:60552554 G/C cg16423285 chr20:60520624 NA -0.53 -5.5 -0.44 2.11e-7 Body mass index; TGCT cis rs875971 1.000 rs4718357 chr7:65960878 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.64e-6 Aortic root size; TGCT cis rs2862064 0.929 rs4704837 chr5:156464212 T/G cg12943317 chr5:156479607 HAVCR1 -0.45 -5.29 -0.43 5.36e-7 Platelet count; TGCT cis rs6977660 0.598 rs72591445 chr7:19773035 G/A cg07541023 chr7:19748670 TWISTNB 1.13 7.17 0.54 6.05e-11 Thyroid stimulating hormone; TGCT cis rs2115630 0.691 rs8040066 chr15:85176465 G/C cg12863693 chr15:85201151 NMB -0.41 -5.71 -0.46 7.79e-8 P wave terminal force; TGCT trans rs2688608 0.901 rs2459446 chr10:75601596 C/T cg13918328 chr10:52500089 ASAH2B -0.67 -6.63 -0.51 9.32e-10 Inflammatory bowel disease; TGCT cis rs4595586 0.545 rs6580910 chr12:39390052 C/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs9549367 0.789 rs34989271 chr13:113894766 G/A cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs733175 0.855 rs10022499 chr4:10006537 C/A cg00071950 chr4:10020882 SLC2A9 0.5 4.58 0.38 1.13e-5 Psychosis and Alzheimer's disease; TGCT cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs7829975 0.714 rs7823757 chr8:8670177 T/A cg15556689 chr8:8085844 FLJ10661 0.66 6.07 0.48 1.47e-8 Mood instability; TGCT cis rs1005277 0.579 rs11011461 chr10:38431427 G/A cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs12549902 0.966 rs716199 chr8:41515531 A/G cg21772509 chr8:41503840 NKX6-3 0.85 9.62 0.65 1.04e-16 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs4803468 0.967 rs892044 chr19:41903671 A/G cg09537434 chr19:41945824 ATP5SL -0.89 -10.04 -0.67 9.93e-18 Height; TGCT cis rs2836974 0.932 rs2836955 chr21:40619887 G/A cg17971929 chr21:40555470 PSMG1 0.95 9.22 0.64 9.9e-16 Cognitive function; TGCT cis rs826838 1.000 rs826886 chr12:39095797 A/G cg13010199 chr12:38710504 ALG10B 0.58 4.74 0.39 5.74e-6 Heart rate; TGCT cis rs6547741 0.935 rs4666005 chr2:27855239 A/G cg27432699 chr2:27873401 GPN1 0.18 4.63 0.38 9.2e-6 Oral cavity cancer; TGCT cis rs9916302 0.904 rs10852933 chr17:37698194 G/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs3099143 1.000 rs1398241 chr15:77153386 C/T cg21673338 chr15:77095150 SCAPER -0.51 -4.91 -0.4 2.85e-6 Recalcitrant atopic dermatitis; TGCT cis rs7014346 0.683 rs10956368 chr8:128423650 C/T cg04263511 chr8:128962092 PVT1 0.31 4.54 0.38 1.3e-5 Colorectal cancer; TGCT cis rs7666738 0.830 rs10010698 chr4:98981594 C/T cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.791 rs7657399 chr4:98851861 T/C cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7552404 0.655 rs1146646 chr1:76265500 G/A cg22875332 chr1:76189707 ACADM 0.58 6.53 0.51 1.53e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs4886920 0.563 rs4542627 chr15:78070743 A/T cg03457338 chr15:78040120 NA -0.17 -4.46 -0.37 1.79e-5 Neuroticism; TGCT cis rs11665748 0.538 rs266863 chr19:51355650 A/G cg03104309 chr19:51052080 LRRC4B 0.24 4.46 0.37 1.82e-5 Prostate-specific antigen levels (conditioned on lead SNPs);Prostate-specific antigen levels; TGCT cis rs6674176 0.561 rs7161 chr1:44438974 A/G cg12908607 chr1:44402522 ARTN 0.69 8.47 0.61 6e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg17345569 chr6:42928274 GNMT -0.47 -4.85 -0.4 3.69e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7833790 0.963 rs28823280 chr8:82777716 G/A cg23324259 chr8:82754387 SNX16 0.64 4.52 0.38 1.43e-5 Diastolic blood pressure; TGCT cis rs9611565 0.649 rs139553 chr22:42187199 A/G cg06634786 chr22:41940651 POLR3H 0.8 7.41 0.55 1.69e-11 Vitiligo; TGCT cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg12756686 chr19:29218302 NA 0.78 6.69 0.51 6.93e-10 Methadone dose in opioid dependence; TGCT cis rs10089 1.000 rs6595806 chr5:127499764 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.4 0.55 1.77e-11 Ileal carcinoids; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg14624950 chr17:62577106 SMURF2 0.21 4.67 0.39 7.63e-6 Prudent dietary pattern; TGCT cis rs262150 1.000 rs262149 chr7:158778256 A/G cg19418458 chr7:158789849 NA 0.44 4.51 0.38 1.5e-5 Facial morphology (factor 20); TGCT cis rs7089973 0.624 rs11196930 chr10:116583596 C/T cg03647239 chr10:116582469 FAM160B1 0.58 5.63 0.45 1.16e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9926296 0.656 rs11861084 chr16:89875710 G/T cg27121462 chr16:89883253 FANCA -0.57 -5.17 -0.42 8.93e-7 Vitiligo; TGCT cis rs7095607 0.813 rs960773 chr10:69931720 G/T cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.72e-6 Lung function (FVC); TGCT cis rs36051895 0.659 rs7046511 chr9:5045695 C/T cg02405213 chr9:5042618 JAK2 -0.78 -10.85 -0.7 1.1e-19 Pediatric autoimmune diseases; TGCT cis rs9894429 0.752 rs7502883 chr17:79588557 T/C cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.98e-6 Eye color traits; TGCT cis rs72949976 1.000 rs62186568 chr2:214033955 G/A cg08319019 chr2:214017104 IKZF2 -0.79 -7.3 -0.55 2.97e-11 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs896854 0.902 rs896852 chr8:95960886 G/T cg13393036 chr8:95962371 TP53INP1 -0.63 -8.66 -0.61 2.14e-14 Type 2 diabetes; TGCT cis rs9948 0.521 rs62156207 chr2:97359236 C/A cg01990225 chr2:97406019 LMAN2L -0.9 -4.49 -0.37 1.59e-5 Erectile dysfunction and prostate cancer treatment; TGCT cis rs6964587 0.934 rs7798973 chr7:91588360 G/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs9549367 0.713 rs553316 chr13:113838015 A/G cg09473364 chr13:112927190 NA 0.29 4.64 0.38 8.73e-6 Platelet distribution width; TGCT cis rs2806561 0.514 rs11801120 chr1:23543307 C/T cg19743168 chr1:23544995 NA 0.47 7.78 0.57 2.4e-12 Height; TGCT cis rs453301 0.509 rs7000323 chr8:8792273 G/A cg15556689 chr8:8085844 FLJ10661 -0.61 -4.97 -0.41 2.2e-6 Joint mobility (Beighton score); TGCT cis rs13256369 0.865 rs13277708 chr8:8573936 T/C cg17143192 chr8:8559678 CLDN23 0.63 6.01 0.47 1.96e-8 Obesity-related traits; TGCT cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.11 -0.42 1.18e-6 Bipolar disorder; TGCT cis rs9527 0.568 rs12772775 chr10:104702999 C/A cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs35883536 0.545 rs56674564 chr1:101097718 T/C cg06223162 chr1:101003688 GPR88 0.33 5.45 0.44 2.66e-7 Monocyte count; TGCT cis rs6089584 0.888 rs6142927 chr20:60605848 A/G cg13770153 chr20:60521292 NA -0.49 -6.21 -0.49 7.44e-9 Body mass index; TGCT cis rs4478858 0.684 rs7519766 chr1:31735512 C/A cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs2439831 0.867 rs2412779 chr15:43655927 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs2228479 0.702 rs11076621 chr16:89837927 A/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs11971779 0.648 rs59791374 chr7:139116962 C/T cg07862535 chr7:139043722 LUC7L2 0.66 5.07 0.41 1.42e-6 Diisocyanate-induced asthma; TGCT cis rs1371867 0.846 rs1692006 chr8:101252462 C/T cg00191853 chr8:101177733 SPAG1 0.23 4.67 0.39 7.55e-6 Atrioventricular conduction; TGCT cis rs6121246 0.909 rs3203770 chr20:30382315 A/G cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7843479 1.000 rs66824050 chr8:21815425 T/G cg17168535 chr8:21777572 XPO7 0.64 5.91 0.47 3.12e-8 Mean corpuscular volume; TGCT cis rs11711311 0.824 rs9876528 chr3:113357196 G/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.08 -0.48 1.35e-8 IgG glycosylation; TGCT cis rs3772130 1.000 rs56314138 chr3:121356656 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.55 4.95 0.41 2.35e-6 Cognitive performance; TGCT cis rs3026101 0.671 rs8081481 chr17:5282763 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.52 0.38 1.41e-5 Body mass index; TGCT cis rs7937682 0.575 rs34558891 chr11:111737912 C/T cg09085632 chr11:111637200 PPP2R1B 0.88 8.47 0.61 5.93e-14 Primary sclerosing cholangitis; TGCT cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs4820539 1.000 rs4820539 chr22:23477970 C/T cg21100191 chr22:23484243 RTDR1 -0.91 -10.92 -0.7 7.27e-20 Bone mineral density; TGCT cis rs6964587 0.839 rs6949700 chr7:91467435 A/G cg17063962 chr7:91808500 NA 0.81 8.67 0.61 1.99e-14 Breast cancer; TGCT cis rs11249608 0.548 rs2132671 chr5:178457434 A/G cg21905437 chr5:178450457 ZNF879 -0.45 -4.6 -0.38 1.03e-5 Pubertal anthropometrics; TGCT cis rs2153535 0.580 rs5001322 chr6:8451608 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs77972916 0.505 rs3851318 chr2:43532808 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -6.16 -0.48 9.38e-9 Granulocyte percentage of myeloid white cells; TGCT cis rs2997447 0.761 rs61776618 chr1:26456709 A/G cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs6565180 0.963 rs4787642 chr16:30359408 T/C cg17640201 chr16:30407289 ZNF48 -0.88 -8.6 -0.61 2.91e-14 Tonsillectomy; TGCT cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg24829409 chr8:58192753 C8orf71 0.51 4.51 0.38 1.47e-5 Developmental language disorder (linguistic errors); TGCT cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs514406 0.861 rs2448792 chr1:53268313 T/C cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT trans rs66573146 1.000 rs6812391 chr4:6963893 G/A cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs1532993 0.518 rs6832426 chr4:98567966 G/A cg05340658 chr4:99064831 C4orf37 -0.42 -5.05 -0.41 1.57e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6582630 0.555 rs11182429 chr12:38526679 A/C cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.37e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6866344 0.697 rs11742808 chr5:178131658 G/A cg03877680 chr5:178157825 ZNF354A 0.75 6.1 0.48 1.25e-8 Neutrophil percentage of white cells; TGCT cis rs797680 0.786 rs59417472 chr1:93848513 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.51 -0.44 2.01e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11673344 0.542 rs826328 chr19:37495381 A/C cg08039142 chr19:36980659 ZNF566 0.57 5.44 0.44 2.74e-7 Obesity-related traits; TGCT cis rs9787249 0.957 rs41267029 chr1:40214367 A/G cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs752590 0.887 rs68090726 chr2:113962835 G/C cg27425262 chr2:113953981 PSD4;LOC440839 0.42 4.73 0.39 5.92e-6 Mucinous ovarian carcinoma; TGCT cis rs6089584 0.527 rs927589 chr20:60606363 A/G cg06108461 chr20:60628389 TAF4 -0.44 -5.58 -0.45 1.44e-7 Body mass index; TGCT cis rs1008375 0.932 rs11941874 chr4:17666416 C/T cg18681998 chr4:17616180 MED28 -0.91 -9.5 -0.65 2.08e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7980687 0.627 rs1727325 chr12:123698332 G/C cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Height;Educational attainment;Head circumference (infant); TGCT cis rs7772486 0.846 rs9403767 chr6:146402386 G/T cg05347473 chr6:146136440 FBXO30 0.52 4.82 0.4 4.11e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg04025307 chr7:1156635 C7orf50 0.23 5.42 0.44 2.94e-7 Longevity;Endometriosis; TGCT cis rs9814567 0.752 rs13084192 chr3:134336095 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.75 6.75 0.52 4.98e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9733 0.596 rs34140753 chr1:150642583 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs5167 0.566 rs7253458 chr19:45482570 C/T cg09555818 chr19:45449301 APOC2 0.23 4.62 0.38 9.53e-6 Blood protein levels; TGCT cis rs6840360 0.869 rs55668815 chr4:152473828 C/G cg17479576 chr4:152424074 FAM160A1 -0.46 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs66716358 0.800 rs4755809 chr11:44323193 A/G cg02785814 chr11:44338707 NA -0.46 -4.66 -0.39 8.04e-6 Monobrow; TGCT cis rs2456568 0.803 rs10831140 chr11:93640689 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.35 -0.5 3.67e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7089973 0.604 rs17663387 chr10:116588060 C/G cg03647239 chr10:116582469 FAM160B1 0.6 5.86 0.47 4e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs28595532 0.748 rs72670249 chr4:119336823 G/T cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs9733 0.596 rs6685702 chr1:150656307 A/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.51 0.38 1.5e-5 Tonsillectomy; TGCT cis rs9682041 0.740 rs6444929 chr3:170150076 C/T cg11886554 chr3:170076028 SKIL 0.93 6.78 0.52 4.32e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs11690935 0.885 rs6725388 chr2:172730015 G/C cg13550731 chr2:172543902 DYNC1I2 -0.9 -8.17 -0.59 3.02e-13 Schizophrenia; TGCT cis rs6138458 0.620 rs2151462 chr20:24911823 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs3087591 1.000 rs2905795 chr17:29547601 A/G cg24425628 chr17:29625626 OMG;NF1 0.48 7.42 0.55 1.65e-11 Hip circumference; TGCT cis rs6450176 0.597 rs1541682 chr5:53304401 C/T ch.5.1024479R chr5:53302184 ARL15 -0.83 -6.16 -0.48 9.32e-9 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT trans rs12145833 1.000 rs10926984 chr1:243462153 T/G cg15780870 chr12:130953802 RIMBP2 0.48 6.73 0.52 5.57e-10 Obesity (early onset extreme); TGCT trans rs8073060 0.559 rs17550632 chr17:33890883 G/C cg19694781 chr19:47549865 TMEM160 0.6 13.13 0.76 3.12e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2806561 0.704 rs1757039 chr1:23508657 A/G cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs2742417 0.624 rs2742394 chr3:45757591 C/T cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1005277 0.541 rs2505193 chr10:38394638 G/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs7226408 0.857 rs10502666 chr18:34423393 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2576037 0.583 rs478820 chr18:44397782 G/A cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs2836950 0.501 rs11702505 chr21:40700614 G/T cg06238570 chr21:40685208 BRWD1 -0.64 -6.56 -0.51 1.34e-9 Menarche (age at onset); TGCT cis rs12693043 0.727 rs3205060 chr2:175425346 C/T cg11778734 chr2:175439522 WIPF1 -0.38 -4.89 -0.4 3.05e-6 Urate levels (BMI interaction); TGCT cis rs2469997 1.000 rs2470026 chr8:120365112 C/T cg00681363 chr8:120844660 TAF2 -0.72 -4.63 -0.38 8.98e-6 Hypertension (SNP x SNP interaction); TGCT cis rs6460942 1.000 rs75564554 chr7:12319362 A/C cg06484146 chr7:12443880 VWDE -0.54 -4.55 -0.38 1.26e-5 Coronary artery disease; TGCT cis rs9399135 0.967 rs9376082 chr6:135346389 T/A cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs2361718 0.501 rs8065486 chr17:78138196 A/G cg09238746 chr17:78121135 EIF4A3 1.01 11.13 0.71 2.2e-20 Yeast infection; TGCT cis rs1949733 0.877 rs940133 chr4:8473614 T/C cg13073564 chr4:8508604 NA -0.5 -5.04 -0.41 1.63e-6 Response to antineoplastic agents; TGCT cis rs6951245 0.554 rs75075857 chr7:1140298 C/T cg18402987 chr7:1209562 NA 0.47 4.78 0.39 4.93e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg02353165 chr6:42928485 GNMT -0.9 -9.26 -0.64 7.66e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2766547 0.647 rs2766541 chr6:35707331 T/C cg01618151 chr6:35707957 C6orf81 -0.27 -4.63 -0.38 9.02e-6 Eosinophil percentage of granulocytes; TGCT cis rs6964587 0.839 rs13246743 chr7:91453945 G/T cg17063962 chr7:91808500 NA 0.82 8.31 0.6 1.43e-13 Breast cancer; TGCT cis rs853679 0.517 rs9368554 chr6:28082711 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg05665937 chr4:1216051 CTBP1 0.25 4.75 0.39 5.64e-6 Obesity-related traits; TGCT cis rs9486715 0.867 rs2499775 chr6:97007340 C/T cg18709589 chr6:96969512 KIAA0776 -0.86 -8.45 -0.6 6.73e-14 Headache; TGCT cis rs6424115 0.931 rs2473377 chr1:24148260 T/C cg15997130 chr1:24165203 NA 0.9 10.23 0.68 3.51e-18 Immature fraction of reticulocytes; TGCT cis rs2074977 0.550 rs11085020 chr19:3446107 C/T cg08380311 chr19:3435252 NFIC -0.72 -6.45 -0.5 2.32e-9 Height; TGCT cis rs644799 1.000 rs3748256 chr11:95521953 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.53 0.61 4.41e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9910055 0.502 rs1684662 chr17:42180822 T/A cg19774624 chr17:42201019 HDAC5 0.71 6.72 0.52 5.98e-10 Total body bone mineral density; TGCT cis rs35160687 0.901 rs13020869 chr2:86523360 C/T cg12542933 chr2:85804724 VAMP8 0.4 4.81 0.4 4.21e-6 Night sleep phenotypes; TGCT cis rs1775715 0.870 rs7912121 chr10:32228995 T/G cg14930904 chr10:32216787 ARHGAP12 0.49 4.6 0.38 1.03e-5 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs12693043 1.000 rs12693043 chr2:175377565 C/T cg11778734 chr2:175439522 WIPF1 0.41 5.1 0.42 1.25e-6 Urate levels (BMI interaction); TGCT cis rs4700695 0.698 rs416369 chr5:65231058 C/T cg21114390 chr5:65439923 SFRS12 0.56 4.44 0.37 1.99e-5 Facial morphology (factor 19); TGCT cis rs589448 0.902 rs528974 chr12:69765918 A/T cg20891283 chr12:69753455 YEATS4 0.9 10.36 0.68 1.69e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs7659604 0.518 rs17452156 chr4:122733623 T/C cg19748678 chr4:122722346 EXOSC9 0.9 9.34 0.64 4.9e-16 Type 2 diabetes; TGCT cis rs1862618 0.671 rs832531 chr5:56228401 A/G cg12311346 chr5:56204834 C5orf35 -0.57 -6.06 -0.48 1.51e-8 Initial pursuit acceleration; TGCT cis rs9926296 0.568 rs7203907 chr16:89833774 C/G cg26513180 chr16:89883248 FANCA 1.04 14.77 0.8 4.11e-29 Vitiligo; TGCT cis rs4073582 0.595 rs1151540 chr11:66041807 A/C cg16950941 chr11:66035639 RAB1B 0.57 5.33 0.43 4.49e-7 Gout; TGCT cis rs2841277 0.646 rs3742935 chr14:105405599 G/C cg21017887 chr14:105400489 NA 0.37 5.19 0.42 8.23e-7 Rheumatoid arthritis; TGCT cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.39 -4.9 -0.4 2.97e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6460942 0.778 rs74993124 chr7:12462917 A/G cg06484146 chr7:12443880 VWDE -0.53 -5.59 -0.45 1.36e-7 Coronary artery disease; TGCT cis rs7192750 0.586 rs9806882 chr16:71925511 G/T cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs5750830 0.649 rs5750814 chr22:39797987 T/C cg01416388 chr22:39784598 NA -0.73 -7.59 -0.56 6.65e-12 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.966 rs7675735 chr4:17587137 T/A cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs8180040 0.701 rs34103310 chr3:47073266 C/T cg27129171 chr3:47204927 SETD2 0.74 9.79 0.66 4.15e-17 Colorectal cancer; TGCT cis rs16867321 0.694 rs721301 chr2:181387265 A/G cg23363182 chr2:181467187 NA 0.39 6.02 0.48 1.86e-8 Obesity; TGCT cis rs7429990 0.932 rs7630685 chr3:48131170 G/C cg11946769 chr3:48343235 NME6 -0.55 -4.49 -0.37 1.62e-5 Educational attainment (years of education); TGCT cis rs933688 1.000 rs10041402 chr5:90738948 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.09 9.69 0.66 7.22e-17 Smoking behavior; TGCT cis rs13082711 0.595 rs4973761 chr3:27358620 T/C cg02860705 chr3:27208620 NA 0.48 7.37 0.55 2.15e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs7119038 0.629 rs11217000 chr11:118604984 A/G cg19308663 chr11:118741387 NA 0.26 4.82 0.4 4.05e-6 Sjögren's syndrome; TGCT cis rs7104764 0.833 rs12574034 chr11:212262 T/C cg18336825 chr11:236787 PSMD13;SIRT3 -0.71 -6.75 -0.52 5.12e-10 Menarche (age at onset); TGCT cis rs17376456 0.877 rs12716457 chr5:93397627 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs9913156 0.696 rs72835620 chr17:4558128 G/A cg00122941 chr17:4613640 ARRB2 0.87 7.38 0.55 1.95e-11 Lymphocyte counts; TGCT cis rs7267979 1.000 rs2258719 chr20:25275843 C/T cg14121845 chr20:25566513 NINL 0.51 5.5 0.44 2.05e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6840360 0.642 rs4263379 chr4:152399131 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs9467773 1.000 rs9357010 chr6:26527945 C/G cg26531700 chr6:26746687 NA 0.51 5.15 0.42 9.84e-7 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.848 rs4955411 chr3:49145304 A/G cg07636037 chr3:49044803 WDR6 0.77 6.08 0.48 1.34e-8 Menarche (age at onset); TGCT cis rs459571 0.959 rs461462 chr9:136911272 C/T cg14405625 chr9:136855902 VAV2 -0.3 -4.54 -0.38 1.3e-5 Platelet distribution width; TGCT cis rs13191362 0.938 rs28360532 chr6:162997477 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7582180 0.638 rs9973536 chr2:100942243 C/T cg14675211 chr2:100938903 LONRF2 0.51 5.02 0.41 1.72e-6 Intelligence (multi-trait analysis); TGCT cis rs11578119 0.933 rs12123065 chr1:170396098 C/T cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.67e-8 Male-pattern baldness; TGCT cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg24675658 chr1:53192096 ZYG11B 0.76 8.75 0.62 1.3e-14 Monocyte count; TGCT trans rs877282 0.898 rs12356709 chr10:763365 A/G cg22713356 chr15:30763199 NA 1.2 9.16 0.64 1.36e-15 Uric acid levels; TGCT cis rs1552244 0.572 rs17032440 chr3:10169819 A/C cg02579736 chr3:10068473 FANCD2;CIDECP -0.9 -5.35 -0.43 4.1e-7 Alzheimer's disease; TGCT cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg26818010 chr10:134567672 INPP5A -0.35 -4.45 -0.37 1.86e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7959452 0.590 rs6581889 chr12:69757429 T/C cg11871910 chr12:69753446 YEATS4 0.82 8.82 0.62 8.61e-15 Blood protein levels; TGCT cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg10411590 chr13:21900810 NA 0.38 5.06 0.41 1.48e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.24e-9 Blood metabolite levels; TGCT cis rs2797160 1.000 rs13328298 chr6:126016580 G/A cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs7267979 0.668 rs2387977 chr20:25599776 C/T cg03522245 chr20:25566470 NINL -0.49 -5.32 -0.43 4.66e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8054556 0.787 rs3814877 chr16:30042677 G/T cg24235633 chr16:29875177 LOC440356;CDIPT 0.2 4.51 0.38 1.49e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs12049351 0.774 rs12079612 chr1:229649372 T/C cg12130225 chr1:229698885 NA 0.36 4.46 0.37 1.8e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs10791323 0.569 rs11533204 chr11:133743644 A/G cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs11711311 0.747 rs2895415 chr3:113345565 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.61 -5.03 -0.41 1.66e-6 IgG glycosylation; TGCT cis rs12791968 0.765 rs12790121 chr11:45001089 G/A cg11846598 chr11:44996168 LOC221122 -0.31 -5.02 -0.41 1.79e-6 Inhibitory control; TGCT trans rs1005277 0.563 rs2800550 chr10:38482929 T/C cg17830980 chr10:43048298 ZNF37B -0.84 -10.46 -0.68 9.38e-19 Extrinsic epigenetic age acceleration; TGCT cis rs7666738 0.830 rs4699588 chr4:98973789 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs210152 0.588 rs449978 chr6:33496060 G/A cg22108809 chr5:56777663 ACTBL2 -0.54 -6.67 -0.51 7.44e-10 Schizophrenia; TGCT cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg10295955 chr4:187884368 NA -0.96 -14.18 -0.79 9.89e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs3785574 0.962 rs2584623 chr17:61906679 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.45 0.44 2.66e-7 Height; TGCT cis rs79349575 0.687 rs12602179 chr17:47010034 G/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs10206020 0.921 rs9678719 chr2:1549628 A/G cg12573674 chr2:1569213 NA -0.49 -4.95 -0.41 2.41e-6 IgG glycosylation; TGCT cis rs6500602 0.647 rs4786514 chr16:4576798 A/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 6.01 0.48 1.88e-8 Schizophrenia; TGCT cis rs1218582 0.772 rs7528532 chr1:154874440 C/T cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs1797081 0.840 rs10904820 chr10:16848473 A/G cg23933602 chr10:16859644 RSU1 0.97 11.98 0.73 1.93e-22 Platelet distribution width; TGCT cis rs7926906 1.000 rs10741375 chr11:90521800 G/A cg26138821 chr11:89956704 CHORDC1 -0.51 -5.52 -0.44 1.92e-7 Intelligence (multi-trait analysis); TGCT cis rs71435601 0.574 rs1652420 chr2:21383881 A/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg20637647 chr7:64974828 NA 0.84 4.85 0.4 3.63e-6 Diabetic kidney disease; TGCT cis rs6831352 0.918 rs28987088 chr4:100059139 T/C cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs4700695 0.764 rs10066817 chr5:65319853 A/G cg21114390 chr5:65439923 SFRS12 0.6 4.47 0.37 1.74e-5 Facial morphology (factor 19); TGCT cis rs2249625 0.545 rs10498880 chr6:72882183 G/T cg08500200 chr6:72892038 RIMS1 0.43 4.61 0.38 1e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs1552244 0.572 rs67439440 chr3:10169503 C/T cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs1008375 1.000 rs1121091 chr4:17676386 A/C cg16339924 chr4:17578868 LAP3 0.53 4.62 0.38 9.58e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3782455 0.793 rs77046876 chr12:114404271 G/A cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6912958 0.702 rs2300909 chr6:88212100 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs9322193 0.923 rs57012784 chr6:149948827 G/A cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs112158604 1 rs112158604 chr1:150696792 TCTTCTGCAG/T cg13175981 chr1:150552382 MCL1 0.43 4.78 0.39 4.88e-6 Lymphocyte counts; TGCT cis rs7586879 0.681 rs6545790 chr2:25109302 A/G cg15423357 chr2:25149977 NA 0.51 4.84 0.4 3.79e-6 Body mass index; TGCT cis rs9300255 0.602 rs1616181 chr12:123619856 T/A cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs2204008 0.811 rs11525004 chr12:38333807 T/A cg26384229 chr12:38710491 ALG10B 0.83 7.19 0.54 5.37e-11 Bladder cancer; TGCT cis rs514406 0.758 rs532242 chr1:53308665 C/G cg24675658 chr1:53192096 ZYG11B -0.7 -7.76 -0.57 2.67e-12 Monocyte count; TGCT cis rs9430161 0.579 rs11576658 chr1:11037736 C/T cg27631724 chr1:11040367 C1orf127 0.55 6.05 0.48 1.55e-8 Ewing sarcoma; TGCT cis rs589448 0.902 rs2603089 chr12:69776800 C/T cg11871910 chr12:69753446 YEATS4 -0.89 -10.53 -0.69 6.39e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs7772486 0.738 rs2246334 chr6:146183635 G/A cg05347473 chr6:146136440 FBXO30 0.55 5.22 0.42 7.17e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2120019 1.000 rs8033837 chr15:75353975 A/C cg09165964 chr15:75287851 SCAMP5 -1.18 -10.44 -0.68 1.07e-18 Blood trace element (Zn levels); TGCT cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg07061783 chr6:25882402 NA -0.64 -6.25 -0.49 6.11e-9 Intelligence (multi-trait analysis); TGCT cis rs4295623 0.559 rs2409836 chr8:11689228 T/G cg02840367 chr8:11660030 FDFT1 -0.66 -5.43 -0.44 2.79e-7 Morning vs. evening chronotype; TGCT cis rs9467711 0.651 rs34555420 chr6:26090270 G/T cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs908922 0.676 rs10788842 chr1:152514588 A/T cg20991723 chr1:152506922 NA 0.46 6.17 0.48 8.79e-9 Hair morphology; TGCT cis rs10479542 0.630 rs6879664 chr5:178974576 T/G cg14851468 chr5:179071604 C5orf60 0.25 4.86 0.4 3.46e-6 Lung cancer; TGCT cis rs28595532 0.920 rs73842253 chr4:119721856 G/A cg14228332 chr4:119757509 SEC24D 1.22 6.12 0.48 1.12e-8 Cannabis dependence symptom count; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg15687855 chr3:44754131 ZNF502 -0.55 -6.8 -0.52 3.9e-10 Depressive symptoms; TGCT cis rs9443645 0.869 rs7762022 chr6:79502859 C/A cg09184832 chr6:79620586 NA -0.45 -4.84 -0.4 3.76e-6 Intelligence (multi-trait analysis); TGCT cis rs317689 0.513 rs317659 chr12:69686132 T/A cg14784868 chr12:69753453 YEATS4 0.66 6.45 0.5 2.31e-9 Response to diuretic therapy; TGCT cis rs2456568 0.867 rs2456569 chr11:93691393 C/A cg26875233 chr11:93583750 C11orf90 -0.45 -5.84 -0.46 4.35e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg10207240 chr12:122356781 WDR66 0.33 4.54 0.38 1.31e-5 Mean corpuscular volume; TGCT cis rs7226408 0.802 rs1445529 chr18:34512757 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT trans rs17471911 0.786 rs11189952 chr10:100808370 G/A cg03484267 chr2:207988651 KLF7 -0.52 -6.67 -0.51 7.53e-10 Neuroticism; TGCT cis rs2153535 0.580 rs6902001 chr6:8477055 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs13256369 0.802 rs13281933 chr8:8562665 C/A cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs12579753 0.872 rs11519752 chr12:82207300 A/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs7937682 0.889 rs497111 chr11:111499512 G/A cg09085632 chr11:111637200 PPP2R1B -1.11 -11.7 -0.72 9.24e-22 Primary sclerosing cholangitis; TGCT cis rs12681288 0.723 rs35425201 chr8:971062 C/T cg04851639 chr8:1020857 NA -0.31 -5.13 -0.42 1.07e-6 Schizophrenia; TGCT cis rs151997 0.962 rs27714 chr5:50180396 G/C cg06027927 chr5:50259733 NA 0.46 4.61 0.38 9.69e-6 Callous-unemotional behaviour; TGCT cis rs12950390 0.853 rs11658511 chr17:45856918 T/C cg06532163 chr17:45867833 NA 0.37 5.89 0.47 3.46e-8 IgG glycosylation; TGCT cis rs7959452 0.868 rs10878967 chr12:69740869 T/C cg20891283 chr12:69753455 YEATS4 0.69 6.81 0.52 3.67e-10 Blood protein levels; TGCT cis rs861020 0.630 rs599649 chr1:210003402 T/C cg05527609 chr1:210001259 C1orf107 0.87 7.64 0.57 5.03e-12 Orofacial clefts; TGCT cis rs10875746 0.903 rs61918774 chr12:48448134 C/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs921968 0.643 rs596076 chr2:219451015 T/G cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs854765 0.663 rs1052299 chr17:17750419 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.73 -7.04 -0.53 1.17e-10 Total body bone mineral density; TGCT cis rs524023 1.000 rs12786214 chr11:64364203 G/A cg07733098 chr11:64478343 NRXN2 0.32 4.87 0.4 3.4e-6 Urate levels in obese individuals; TGCT cis rs12620999 0.627 rs12986628 chr2:238103439 C/T cg23555395 chr2:238036564 NA -0.28 -4.95 -0.41 2.4e-6 Systemic lupus erythematosus; TGCT cis rs6500602 0.727 rs3761681 chr16:4566857 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.33 6.06 0.48 1.5e-8 Schizophrenia; TGCT cis rs301043 0.697 rs2923014 chr12:95854146 G/T cg07805603 chr12:95869602 METAP2 0.33 4.47 0.37 1.75e-5 Immature fraction of reticulocytes; TGCT cis rs1903068 0.657 rs73236104 chr4:55990954 G/C cg09978860 chr4:56023921 NA 0.54 5.48 0.44 2.26e-7 Endometriosis; TGCT cis rs2188554 0.958 rs73480753 chr7:117027181 C/T cg08576598 chr7:116962626 WNT2 -0.4 -4.72 -0.39 6.15e-6 Esophageal adenocarcinoma; TGCT cis rs6831352 0.760 rs2602859 chr4:100030583 G/A cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Alcohol dependence; TGCT cis rs9649213 0.614 rs1006169 chr7:97938443 A/G cg09267113 chr7:98030324 BAIAP2L1 0.92 8.37 0.6 1.01e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs13064411 0.696 rs6808394 chr3:113122524 T/G cg18753928 chr3:113234510 CCDC52 -0.7 -5.12 -0.42 1.12e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs13082711 0.689 rs34946790 chr3:27345170 G/A cg02860705 chr3:27208620 NA 0.56 8.75 0.62 1.3e-14 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs4252435 0.522 rs4252443 chr7:142621201 C/G cg09833174 chr7:143059591 FAM131B -0.93 -4.5 -0.37 1.56e-5 Cancer; TGCT cis rs28595532 0.920 rs115838006 chr4:119754356 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs13217239 0.574 rs9366680 chr6:27006123 A/T cg15659132 chr6:26577336 NA 0.52 5.29 0.43 5.35e-7 Schizophrenia; TGCT cis rs4851251 1.000 rs62150284 chr2:100784118 T/C cg22139774 chr2:100720529 AFF3 0.4 5.68 0.45 8.94e-8 Educational attainment (years of education); TGCT cis rs9309473 0.606 rs77962988 chr2:73886090 T/C cg07208825 chr2:73871855 ALMS1P 0.28 5.35 0.43 4.16e-7 Metabolite levels; TGCT cis rs12142240 0.698 rs55670684 chr1:46835139 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.83 -0.4 3.88e-6 Menopause (age at onset); TGCT cis rs2797160 0.967 rs8180614 chr6:126000599 G/C cg05901451 chr6:126070800 HEY2 -0.74 -6.48 -0.5 1.96e-9 Endometrial cancer; TGCT cis rs151997 1.000 rs42415 chr5:50207442 T/A cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs10992471 0.603 rs1121978 chr9:95140351 T/G cg14631576 chr9:95140430 CENPP -0.33 -4.99 -0.41 2.02e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs270601 0.770 rs4361510 chr5:131599647 C/T cg12564285 chr5:131593104 PDLIM4 0.4 4.77 0.39 5.18e-6 Acylcarnitine levels; TGCT cis rs7267979 1.000 rs4815417 chr20:25379526 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1552244 0.882 rs2130813 chr3:10038706 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs769267 1.000 rs2301669 chr19:19453560 C/A cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs7208859 0.673 rs9915139 chr17:29158515 A/G cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1799949 0.894 rs71367985 chr17:41374463 G/A cg05368731 chr17:41323189 NBR1 1.1 12.74 0.75 2.71e-24 Menopause (age at onset); TGCT cis rs2303745 0.589 rs1864116 chr19:17393015 C/T cg02221750 chr19:17393354 ANKLE1 -0.48 -6.27 -0.49 5.46e-9 Systemic lupus erythematosus; TGCT cis rs875971 0.862 rs10250544 chr7:65766561 A/G cg11764359 chr7:65958608 NA -0.55 -5.0 -0.41 1.94e-6 Aortic root size; TGCT cis rs7043114 0.525 rs12353096 chr9:95031144 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.56 -5.5 -0.44 2.11e-7 Height; TGCT cis rs11148252 0.532 rs9536262 chr13:53303074 A/C cg02158880 chr13:53174818 NA -0.43 -5.07 -0.41 1.39e-6 Lewy body disease; TGCT trans rs1005277 0.579 rs1614236 chr10:38502996 C/T cg17830980 chr10:43048298 ZNF37B -0.82 -10.26 -0.68 2.99e-18 Extrinsic epigenetic age acceleration; TGCT cis rs7733403 1 rs7733403 chr5:140154215 A/G cg19875535 chr5:140030758 IK 0.37 6.23 0.49 6.56e-9 Schizophrenia; TGCT cis rs700590 0.723 rs160044 chr5:88114476 T/C cg22951263 chr5:87985283 NA 0.55 5.33 0.43 4.45e-7 Educational attainment (years of education); TGCT cis rs28493229 0.708 rs80003555 chr19:41160612 C/G cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.16 0.42 9.45e-7 Kawasaki disease; TGCT cis rs910316 0.967 rs175451 chr14:75589729 C/T cg08847533 chr14:75593920 NEK9 -0.94 -10.33 -0.68 2.03e-18 Height; TGCT cis rs6740731 0.518 rs13034360 chr2:145293154 C/T cg07679370 chr2:145795797 NA 0.27 5.11 0.42 1.19e-6 Coronary artery disease; TGCT cis rs614226 1.000 rs563920 chr12:121017439 A/G cg10072921 chr12:121022843 NA -0.44 -4.73 -0.39 6.09e-6 Type 1 diabetes nephropathy; TGCT cis rs117785887 0.536 rs12216492 chr6:146376618 T/C cg06708562 chr6:146285465 SHPRH -0.85 -5.1 -0.42 1.25e-6 Interleukin-17 levels; TGCT cis rs7681440 0.804 rs1442140 chr4:90816023 A/G cg26578617 chr4:90757533 SNCA -0.45 -4.77 -0.39 5.06e-6 Dementia with Lewy bodies; TGCT cis rs7542091 0.704 rs12022221 chr1:210046178 A/C cg21951975 chr1:209979733 IRF6 0.57 5.8 0.46 5.31e-8 Monobrow; TGCT cis rs7772486 0.713 rs79248977 chr6:146319388 C/A cg23711669 chr6:146136114 FBXO30 0.84 8.53 0.61 4.35e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs9911578 0.935 rs6503878 chr17:56884581 T/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs910316 0.591 rs7157158 chr14:75457238 A/G cg08847533 chr14:75593920 NEK9 0.83 8.89 0.62 5.99e-15 Height; TGCT cis rs4919694 1.000 rs74749600 chr10:104732996 T/C cg04362960 chr10:104952993 NT5C2 1.07 7.15 0.54 6.49e-11 Arsenic metabolism; TGCT cis rs59964204 0.530 rs73342272 chr7:37026712 G/A cg06458904 chr7:36312573 EEPD1 0.46 4.85 0.4 3.68e-6 Plasma androstenedione levels in resected early stage-receptor positive breast cancer; TGCT cis rs6570726 0.537 rs1280279 chr6:145884048 G/T cg23711669 chr6:146136114 FBXO30 0.74 5.81 0.46 4.96e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg07424592 chr7:64974309 NA 1.22 7.36 0.55 2.2e-11 Diabetic kidney disease; TGCT cis rs2760061 0.583 rs708113 chr1:228192753 T/A cg18477163 chr1:228402036 OBSCN 0.34 6.91 0.53 2.25e-10 Diastolic blood pressure; TGCT cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg14827481 chr10:134361889 INPP5A 0.27 4.43 0.37 2.01e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs832540 0.618 rs41106 chr5:56145057 G/T cg24531977 chr5:56204891 C5orf35 -0.54 -5.34 -0.43 4.33e-7 Coronary artery disease; TGCT cis rs3741404 0.620 rs882147 chr11:63976689 T/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 8.19 0.59 2.67e-13 Platelet count; TGCT cis rs10207060 0.500 rs7566489 chr2:240703985 C/T cg15726768 chr2:241314588 NA -0.32 -4.58 -0.38 1.1e-5 Obesity-related traits; TGCT cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg21280719 chr6:42927975 GNMT -0.37 -4.59 -0.38 1.07e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6674176 0.932 rs4660761 chr1:44440146 G/A cg13606994 chr1:44402422 ARTN -0.47 -4.7 -0.39 6.93e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs66573146 1.000 rs6838250 chr4:6973184 C/G cg01220768 chr4:7056774 TADA2B 0.39 4.91 0.4 2.77e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1256061 0.533 rs2357479 chr14:64792764 G/T cg21174375 chr14:64681225 SYNE2 0.21 4.49 0.37 1.61e-5 Hemoglobin concentration;Red blood cell count;Hematocrit; TGCT cis rs4819052 1.000 rs4818769 chr21:46667451 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.79 6.08 0.48 1.35e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2404602 0.583 rs35707798 chr15:76565026 G/C cg22467129 chr15:76604101 ETFA -0.61 -7.93 -0.58 1.07e-12 Blood metabolite levels; TGCT cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.95e-10 Bipolar disorder; TGCT cis rs7772486 0.875 rs9403768 chr6:146406458 A/C cg05347473 chr6:146136440 FBXO30 0.54 5.09 0.42 1.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs916888 0.821 rs199507 chr17:44858855 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3617 0.625 rs2240917 chr3:52851137 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.6 -0.38 1.02e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs12762955 0.519 rs7094331 chr10:1022816 T/C cg20503657 chr10:835505 NA -0.37 -4.79 -0.4 4.61e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs7772486 0.875 rs1330939 chr6:146308518 T/A cg05347473 chr6:146136440 FBXO30 0.52 4.92 0.4 2.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11098499 0.722 rs10006192 chr4:120263022 T/C cg09307838 chr4:120376055 NA 0.55 5.41 0.44 3.16e-7 Corneal astigmatism; TGCT cis rs526231 0.543 rs34765 chr5:102506864 G/C cg23492399 chr5:102201601 PAM -0.51 -4.49 -0.37 1.6e-5 Primary biliary cholangitis; TGCT cis rs597539 0.615 rs583182 chr11:68678634 C/T cg06112835 chr11:68658793 MRPL21 0.46 7.94 0.58 1.01e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs514406 0.861 rs1412706 chr1:53237721 G/A cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs8180040 0.726 rs4682844 chr3:46982737 T/C cg27129171 chr3:47204927 SETD2 -0.71 -8.76 -0.62 1.25e-14 Colorectal cancer; TGCT cis rs10501293 0.746 rs7936295 chr11:43004672 T/C cg03447554 chr11:43094025 NA 0.44 6.39 0.5 3.03e-9 Cognitive performance; TGCT cis rs425277 0.628 rs262668 chr1:2082602 A/G cg03732007 chr1:2071316 PRKCZ 0.28 6.63 0.51 9.05e-10 Height; TGCT cis rs11249608 0.548 rs7732719 chr5:178463054 A/G cg21905437 chr5:178450457 ZNF879 0.44 4.55 0.38 1.25e-5 Pubertal anthropometrics; TGCT cis rs7918232 0.698 rs6482586 chr10:27297829 A/C cg14442939 chr10:27389572 ANKRD26 0.58 4.63 0.38 9.13e-6 Breast cancer; TGCT cis rs9467711 0.606 rs66827971 chr6:26365766 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7264396 0.747 rs2425112 chr20:34319775 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs910316 0.967 rs175502 chr14:75533679 A/G cg11812906 chr14:75593930 NEK9 -0.73 -7.08 -0.54 9.42e-11 Height; TGCT cis rs12477438 0.700 rs10190421 chr2:99670711 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs1005277 0.579 rs1780122 chr10:38529509 C/A cg25427524 chr10:38739819 LOC399744 -0.4 -8.36 -0.6 1.05e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7677751 0.806 rs7682912 chr4:55085620 T/G cg17187183 chr4:55093834 PDGFRA 0.55 7.13 0.54 7.35e-11 Corneal astigmatism; TGCT cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg23172400 chr8:95962367 TP53INP1 -0.39 -6.44 -0.5 2.4e-9 Type 2 diabetes; TGCT cis rs6087990 0.899 rs1883729 chr20:31363193 G/A cg13636640 chr20:31349939 DNMT3B 1.08 14.21 0.79 8.84e-28 Ulcerative colitis; TGCT cis rs801193 0.569 rs2659907 chr7:66164032 G/A cg11764359 chr7:65958608 NA 0.54 4.85 0.4 3.67e-6 Aortic root size; TGCT trans rs10802346 0.545 rs1770012 chr1:246426405 A/G cg13514129 chr1:39547527 MACF1 0.98 8.97 0.63 3.85e-15 Fractional exhaled nitric oxide (childhood); TGCT cis rs57221529 0.709 rs72707024 chr5:667915 G/A cg09021430 chr5:549028 NA -0.4 -5.52 -0.44 1.9e-7 Lung disease severity in cystic fibrosis; TGCT cis rs12510870 0.599 rs10028276 chr4:74388956 T/C cg05868023 chr4:75230803 EREG 0.55 4.7 0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs889312 0.500 rs11960484 chr5:56109154 C/T cg24531977 chr5:56204891 C5orf35 0.51 5.38 0.43 3.65e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs244731 1.000 rs244729 chr5:176539018 C/G cg06060754 chr5:176797920 RGS14 0.41 5.61 0.45 1.23e-7 Urate levels in lean individuals; TGCT trans rs7618501 1.000 rs7372725 chr3:49790544 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.867 rs2447196 chr15:43893818 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.82 -5.57 -0.45 1.5e-7 Lung cancer in ever smokers; TGCT cis rs7904368 0.754 rs7091240 chr10:16855683 G/A cg14835575 chr10:16859367 RSU1 0.69 7.36 0.55 2.17e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs9929218 0.953 rs3118235 chr16:68732977 A/G cg01251360 chr16:68772225 CDH1 -0.29 -4.65 -0.39 8.45e-6 Colorectal cancer; TGCT cis rs4918072 0.667 rs7920793 chr10:105706446 T/C cg11005552 chr10:105648138 OBFC1 0.34 4.78 0.39 4.93e-6 Coronary artery disease; TGCT cis rs6121246 0.954 rs6089093 chr20:30421459 C/T cg18721089 chr20:30220636 NA -0.46 -4.87 -0.4 3.31e-6 Mean corpuscular hemoglobin; TGCT cis rs12681287 0.752 rs10111095 chr8:87250984 T/C cg27223183 chr8:87520930 FAM82B -0.8 -5.67 -0.45 9.58e-8 Caudate activity during reward; TGCT cis rs7412746 0.611 rs7556661 chr1:150892009 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs6048205 0.764 rs1203907 chr20:22560971 C/T cg10773670 chr20:23331356 NXT1 0.93 4.52 0.38 1.44e-5 Fasting blood glucose (BMI interaction);Fasting blood glucose; TGCT cis rs9467773 1.000 rs4871 chr6:26545632 G/A cg09904177 chr6:26538194 HMGN4 0.64 6.33 0.49 4.12e-9 Intelligence (multi-trait analysis); TGCT cis rs3087591 1.000 rs1800845 chr17:29703438 C/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.52 -0.56 9.58e-12 Hip circumference; TGCT cis rs981844 0.775 rs17371336 chr4:154749525 A/G cg14289246 chr4:154710475 SFRP2 1.0 8.63 0.61 2.53e-14 Response to statins (LDL cholesterol change); TGCT cis rs4665809 1.000 rs750450 chr2:26324631 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.37 -0.5 3.3e-9 Gut microbiome composition (summer); TGCT cis rs2486012 1.000 rs2485991 chr1:44391722 C/T cg12908607 chr1:44402522 ARTN -0.69 -5.84 -0.46 4.28e-8 Intelligence (multi-trait analysis); TGCT cis rs6684514 1.000 rs12563631 chr1:156258953 T/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6547741 1.000 rs6737921 chr2:27839107 T/C cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs11098499 0.863 rs9997631 chr4:120469995 C/G cg09307838 chr4:120376055 NA 0.74 7.31 0.55 2.9e-11 Corneal astigmatism; TGCT cis rs12950390 0.853 rs67441169 chr17:45854462 T/G cg06532163 chr17:45867833 NA 0.37 5.87 0.47 3.74e-8 IgG glycosylation; TGCT cis rs7917772 0.536 rs11191361 chr10:104411958 C/T cg05855489 chr10:104503620 C10orf26 -0.59 -4.91 -0.4 2.76e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg01802117 chr1:53393560 SCP2 -0.46 -5.54 -0.45 1.77e-7 Monocyte count; TGCT cis rs17253792 0.822 rs76201070 chr14:56063604 A/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs916888 0.821 rs199512 chr17:44857352 T/C cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9303401 0.659 rs35103007 chr17:56900738 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs12477438 0.765 rs7605218 chr2:99593080 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs453301 0.686 rs11785634 chr8:8892597 G/T cg00184457 chr8:8946301 NA -0.26 -4.94 -0.41 2.45e-6 Joint mobility (Beighton score); TGCT cis rs6831352 0.918 rs17218162 chr4:100056060 G/A cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT trans rs7618501 0.633 rs11130234 chr3:50024758 G/T cg21659725 chr3:3221576 CRBN 0.76 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis); TGCT cis rs6991838 0.593 rs953593 chr8:66631972 C/T cg14353373 chr8:66472662 NA -0.47 -4.66 -0.39 7.86e-6 Intelligence (multi-trait analysis); TGCT cis rs9291683 0.530 rs11723591 chr4:9985398 T/A cg00071950 chr4:10020882 SLC2A9 0.64 8.17 0.59 3.05e-13 Bone mineral density; TGCT cis rs2404602 0.647 rs12440965 chr15:76958591 G/A cg22467129 chr15:76604101 ETFA 0.47 4.67 0.39 7.62e-6 Blood metabolite levels; TGCT cis rs7246657 0.663 rs10408619 chr19:38070474 C/T cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs10875746 0.807 rs12313300 chr12:48470717 G/A cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT trans rs12599106 0.629 rs1391904 chr16:34548934 C/T cg21548813 chr6:291882 DUSP22 -0.65 -6.9 -0.53 2.41e-10 Menopause (age at onset); TGCT cis rs7100689 0.622 rs1340379 chr10:82121455 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs6964587 1.000 rs34548928 chr7:91668365 G/A cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs7267979 1.000 rs4815404 chr20:25301845 T/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10791097 0.765 rs4622274 chr11:130729486 C/T cg05962950 chr11:130786565 SNX19 0.8 9.6 0.65 1.15e-16 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2276314 1.000 rs2276314 chr18:33557466 C/T cg19628046 chr18:33552617 C18orf21 -0.53 -4.5 -0.37 1.53e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs7020830 0.571 rs7031314 chr9:37376122 A/T cg14235030 chr9:37121269 ZCCHC7 -0.41 -4.57 -0.38 1.16e-5 Schizophrenia; TGCT cis rs77861329 1.000 rs2304505 chr3:52184760 T/C cg08692210 chr3:52188851 WDR51A 0.83 4.64 0.38 8.71e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs3806843 0.900 rs2262576 chr5:140135536 T/C cg19875535 chr5:140030758 IK -0.35 -5.98 -0.47 2.23e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs12908161 0.959 rs12906348 chr15:85329421 A/C cg17173187 chr15:85201210 NMB 0.54 6.06 0.48 1.48e-8 Schizophrenia; TGCT cis rs9910055 0.529 rs183462 chr17:42183376 G/C cg13607699 chr17:42295918 UBTF -0.61 -4.97 -0.41 2.19e-6 Total body bone mineral density; TGCT cis rs910316 0.967 rs4903285 chr14:75609268 A/T cg23033748 chr14:75592666 NEK9 0.28 4.79 0.39 4.73e-6 Height; TGCT cis rs9972944 0.756 rs4791132 chr17:63769124 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs17718580 0.536 rs56208926 chr14:51045042 C/T cg04730355 chr14:51134070 SAV1 1.25 8.77 0.62 1.16e-14 Cognitive performance; TGCT cis rs9560113 1.000 rs9555810 chr13:112181437 C/G cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Vitiligo; TGCT cis rs6138458 1.000 rs6114981 chr20:24974401 C/T cg26195577 chr20:24973756 C20orf3 -1.22 -12.53 -0.75 9.05e-24 Blood protein levels; TGCT cis rs7681440 0.904 rs28734152 chr4:90767359 C/T cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs9436747 0.641 rs6691282 chr1:66046505 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.03 0.41 1.69e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs514406 0.763 rs9988539 chr1:53213884 T/C cg22166914 chr1:53195759 ZYG11B -0.41 -7.06 -0.54 1.05e-10 Monocyte count; TGCT cis rs769267 0.930 rs4808965 chr19:19631655 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs9303401 0.614 rs34920953 chr17:56589406 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.71 6.81 0.52 3.77e-10 Cognitive test performance; TGCT cis rs2067615 0.599 rs12369214 chr12:107198611 G/A cg15890332 chr12:107067104 RFX4 0.28 5.53 0.44 1.8e-7 Heart rate; TGCT cis rs1218582 0.688 rs2135219 chr1:154857217 G/A cg16680214 chr1:154839983 KCNN3 -0.4 -8.47 -0.61 5.8e-14 Prostate cancer; TGCT cis rs909002 0.772 rs6681414 chr1:32070234 G/A cg11573219 chr1:32083031 HCRTR1 -0.45 -5.94 -0.47 2.65e-8 Intelligence (multi-trait analysis); TGCT cis rs11785400 0.793 rs4736364 chr8:143742113 C/T cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs858239 0.730 rs10255155 chr7:23402147 A/T cg05602783 chr7:23145260 KLHL7 0.68 5.74 0.46 6.94e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs12477438 0.501 rs2632260 chr2:99771590 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.05 0.63 2.42e-15 Chronic sinus infection; TGCT cis rs1667284 0.935 rs1791171 chr18:29216157 T/C cg15259973 chr18:29078565 DSG2 0.52 5.04 0.41 1.58e-6 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs4563143 0.514 rs73030738 chr19:29312328 G/A cg04546413 chr19:29218101 NA 0.73 5.36 0.43 3.83e-7 Methadone dose in opioid dependence; TGCT cis rs7666738 0.830 rs13110903 chr4:98946373 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7226408 0.948 rs72883590 chr18:34390793 G/A cg06757138 chr18:34340585 FHOD3 0.26 4.78 0.39 4.78e-6 Obesity-related traits; TGCT cis rs7043114 0.525 rs7847929 chr9:95154244 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.6 -0.45 1.32e-7 Height; TGCT cis rs3741404 0.895 rs1860368 chr11:63994692 T/C cg01727686 chr11:63997306 NUDT22;DNAJC4 -0.23 -4.83 -0.4 4e-6 Platelet count; TGCT cis rs7158300 0.522 rs6575228 chr14:92561395 G/A cg14974772 chr14:92414425 FBLN5 0.24 4.88 0.4 3.25e-6 Height; TGCT cis rs11792861 0.890 rs3750465 chr9:111900677 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.47 0.37 1.73e-5 Menarche (age at onset); TGCT cis rs769267 0.896 rs10405625 chr19:19579046 T/G cg08509172 chr19:19383838 TM6SF2 -0.35 -4.6 -0.38 1.02e-5 Tonsillectomy; TGCT cis rs9325144 0.600 rs6582634 chr12:38748041 G/A cg26384229 chr12:38710491 ALG10B 0.65 6.17 0.48 8.94e-9 Morning vs. evening chronotype; TGCT cis rs55823223 0.564 rs936391 chr17:73847799 A/G cg08125733 chr17:73851984 WBP2 -0.88 -9.52 -0.65 1.87e-16 Psoriasis; TGCT cis rs6835098 0.961 rs1574314 chr4:174106663 C/T cg08422745 chr4:174089978 GALNT7 -0.9 -10.08 -0.67 7.91e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7945705 0.902 rs11042152 chr11:9020987 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.48 5.31 0.43 4.96e-7 Hemoglobin concentration; TGCT trans rs1470506 0.507 rs62171962 chr2:77224930 C/T cg15576869 chr7:50450374 IKZF1 -0.41 -6.76 -0.52 4.74e-10 IgG glycosylation; TGCT cis rs9916302 0.706 rs11078894 chr17:37396805 C/G cg07936489 chr17:37558343 FBXL20 -0.81 -6.1 -0.48 1.27e-8 Glomerular filtration rate (creatinine); TGCT cis rs514406 0.505 rs448788 chr1:53161620 A/G cg08859206 chr1:53392774 SCP2 0.35 4.81 0.4 4.25e-6 Monocyte count; TGCT cis rs9649213 0.614 rs12539761 chr7:98013839 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.96 -9.08 -0.63 2.14e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs78487399 0.808 rs77527404 chr2:43678387 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7843479 0.544 rs11135735 chr8:21791557 C/T cg17168535 chr8:21777572 XPO7 0.91 9.55 0.65 1.52e-16 Mean corpuscular volume; TGCT cis rs4746818 1.000 rs7918066 chr10:70913116 C/T cg11621586 chr10:70884670 VPS26A 1.23 10.93 0.7 6.87e-20 Left atrial antero-posterior diameter; TGCT trans rs114540395 0.858 rs77691531 chr10:103123526 G/A cg10198749 chr1:39920707 MACF1 0.52 7.12 0.54 7.77e-11 Schizophrenia; TGCT cis rs7428 0.924 rs12714140 chr2:85557591 A/T cg24342717 chr2:85555507 TGOLN2 -0.4 -6.35 -0.5 3.76e-9 Ear protrusion; TGCT cis rs425277 0.565 rs3128293 chr1:2065339 A/G cg24578937 chr1:2090814 PRKCZ -0.26 -6.45 -0.5 2.26e-9 Height; TGCT cis rs910316 0.967 rs4903292 chr14:75656245 A/G cg23033748 chr14:75592666 NEK9 0.27 4.54 0.38 1.31e-5 Height; TGCT cis rs2153535 0.580 rs4960423 chr6:8477210 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9611565 0.592 rs12484254 chr22:41962003 T/A cg13695892 chr22:41940480 POLR3H -0.87 -8.17 -0.59 2.95e-13 Vitiligo; TGCT cis rs1348850 0.914 rs1975544 chr2:178465423 G/A cg22681709 chr2:178499509 PDE11A -0.45 -5.26 -0.43 6.13e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs3849570 0.555 rs4481177 chr3:81996817 A/T cg07356753 chr3:81810745 GBE1 0.61 5.39 0.44 3.49e-7 Waist circumference;Body mass index; TGCT cis rs67311347 1.000 rs6801185 chr3:40505060 C/T cg13683864 chr3:40499215 RPL14 1.14 12.22 0.74 4.89e-23 Renal cell carcinoma; TGCT cis rs28595532 0.841 rs115080469 chr4:119720501 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.07 0.59 5.21e-13 Cannabis dependence symptom count; TGCT cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg27286337 chr10:134555280 INPP5A 0.39 4.73 0.39 6.02e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs644799 0.710 rs10831427 chr11:95508383 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.29 0.6 1.54e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4845570 0.920 rs3811414 chr1:151763246 A/G cg07092448 chr1:151763213 TDRKH -1.07 -9.51 -0.65 1.94e-16 Coronary artery disease; TGCT cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg10117171 chr1:25599238 RHD -0.36 -5.85 -0.46 4.18e-8 Erythrocyte sedimentation rate; TGCT cis rs9522267 0.737 rs12429582 chr13:112226657 A/G cg10483660 chr13:112241077 NA -0.31 -5.36 -0.43 4e-7 Hepatitis; TGCT cis rs13064411 0.696 rs6438159 chr3:113217341 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs259282 0.605 rs73028624 chr19:33111758 C/T cg26639809 chr19:33781782 NA 0.24 4.87 0.4 3.27e-6 Schizophrenia; TGCT cis rs9807989 0.811 rs11688573 chr2:102969971 C/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs62193398 0.935 rs17384314 chr2:202531136 C/G cg12618251 chr2:202899058 FZD7 0.53 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs9303542 0.625 rs7207109 chr17:46607817 C/T cg25032089 chr17:46643351 HOXB3 0.57 5.84 0.46 4.27e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs669446 0.562 rs6429636 chr1:44183540 G/T cg12908607 chr1:44402522 ARTN -0.59 -6.47 -0.5 2.02e-9 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs769267 0.930 rs9917108 chr19:19572785 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.2 0.49 7.59e-9 Tonsillectomy; TGCT cis rs9911578 0.967 rs1588322 chr17:56990099 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs4975709 0.589 rs4975744 chr5:1860049 A/G cg14773178 chr5:1868261 NA 0.34 5.34 0.43 4.3e-7 Cardiovascular disease risk factors; TGCT cis rs7586879 0.789 rs13404163 chr2:25126616 A/G cg01884057 chr2:25150051 NA 0.27 4.72 0.39 6.29e-6 Body mass index; TGCT cis rs6665290 0.669 rs34267809 chr1:227176162 C/G cg10327440 chr1:227177885 CDC42BPA -0.91 -15.21 -0.81 4.04e-30 Myeloid white cell count; TGCT cis rs1865760 0.566 rs9358904 chr6:26068566 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.79 7.43 0.55 1.56e-11 Height; TGCT cis rs11785400 0.753 rs9773415 chr8:143731170 G/A cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.79e-7 Schizophrenia; TGCT cis rs425277 0.585 rs364677 chr1:2071765 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 0.35 4.93 0.41 2.55e-6 Height; TGCT cis rs7822232 0.908 rs7821112 chr8:145147169 G/A cg26272248 chr8:145163034 KIAA1875 0.49 4.81 0.4 4.24e-6 Blood metabolite levels; TGCT cis rs35306767 0.903 rs7914758 chr10:891702 T/C cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs12533831 0.654 rs2435609 chr7:150890073 C/T cg26284782 chr7:151513241 PRKAG2 -0.26 -4.46 -0.37 1.79e-5 Childhood ear infection; TGCT cis rs2404602 0.532 rs12591100 chr15:76700801 C/A cg22467129 chr15:76604101 ETFA 0.45 4.93 0.4 2.57e-6 Blood metabolite levels; TGCT cis rs3771570 0.786 rs62186378 chr2:242211554 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs9467603 0.611 rs35789010 chr6:25514179 G/A cg16898833 chr6:26189333 HIST1H4D 1.37 6.03 0.48 1.73e-8 Intelligence (multi-trait analysis); TGCT cis rs7246657 0.722 rs8100646 chr19:38107943 T/C cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs7829975 0.502 rs11785183 chr8:8565957 G/A cg06636001 chr8:8085503 FLJ10661 -0.6 -5.08 -0.42 1.33e-6 Mood instability; TGCT cis rs11098499 0.954 rs71629403 chr4:120372567 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7666738 0.830 rs11725095 chr4:99009711 T/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs10457793 chr6:146415403 A/G cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg18654377 chr3:49208889 KLHDC8B -0.37 -4.9 -0.4 2.91e-6 Menarche (age at onset); TGCT cis rs12422267 0.609 rs11246940 chr12:132623473 A/G cg09764611 chr12:132620959 NA -0.37 -5.68 -0.45 9e-8 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs3784262 0.512 rs4646572 chr15:58343021 T/C cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.57 -0.56 7.4e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9902453 0.689 rs7216948 chr17:28203173 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.27 0.6 1.75e-13 Coffee consumption (cups per day); TGCT cis rs7666738 0.546 rs13141117 chr4:98892798 G/A cg17366294 chr4:99064904 C4orf37 0.64 5.73 0.46 7.05e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs561341 1.000 rs546748 chr17:30324293 A/C cg20587970 chr11:113659929 NA -0.97 -12.38 -0.74 2.11e-23 Hip circumference adjusted for BMI; TGCT cis rs1862618 0.671 rs2591956 chr5:56244604 G/A cg20203395 chr5:56204925 C5orf35 0.53 4.89 0.4 3.03e-6 Initial pursuit acceleration; TGCT cis rs7614311 0.681 rs73119022 chr3:63979834 T/C cg22134162 chr3:63841271 THOC7 -0.43 -5.68 -0.45 9.12e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs11031096 0.655 rs10835734 chr11:4211832 A/C cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1008375 1.000 rs7673500 chr4:17621383 C/T cg18681998 chr4:17616180 MED28 1.03 11.4 0.72 4.96e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs80282103 0.867 rs80254477 chr10:1077387 T/G cg08668510 chr10:1095578 IDI1 1.18 5.51 0.44 2.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs28595532 0.764 rs116302502 chr4:119748848 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs17401966 1.000 rs1536263 chr1:10378914 T/C cg19773385 chr1:10388646 KIF1B -0.22 -4.56 -0.38 1.22e-5 Hepatocellular carcinoma; TGCT cis rs13191362 0.507 rs2849520 chr6:163132038 T/C cg21926612 chr6:163149169 PACRG;PARK2 -0.62 -5.52 -0.44 1.88e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs17345786 0.906 rs72940399 chr3:101122575 A/T cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT trans rs916888 0.821 rs199505 chr17:44859410 A/G cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs922182 0.589 rs11071778 chr15:64237608 A/G cg02919090 chr15:64263738 DAPK2 -0.34 -6.39 -0.5 3e-9 Blood protein levels; TGCT cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg03517284 chr6:25882590 NA 0.5 4.58 0.38 1.12e-5 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs624899 0.655 rs8109248 chr19:11641375 C/T cg14128973 chr19:11649462 CNN1 0.54 6.44 0.5 2.34e-9 Presence of antiphospholipid antibodies; TGCT cis rs12220238 1.000 rs115418388 chr10:75976296 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.79 0.57 2.29e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.91 0.4 2.86e-6 Electroencephalogram traits; TGCT cis rs896854 0.714 rs572547 chr8:95966286 A/G cg09323728 chr8:95962352 TP53INP1 0.45 5.26 0.43 6.17e-7 Type 2 diabetes; TGCT cis rs76878669 0.561 rs10896112 chr11:66116836 G/C cg18002602 chr11:66138449 SLC29A2 -0.54 -6.62 -0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs1552244 1.000 rs2272125 chr3:10138069 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.44 -6.41 -0.5 2.71e-9 Alzheimer's disease; TGCT cis rs7829975 0.688 rs7827182 chr8:8380471 C/G cg15556689 chr8:8085844 FLJ10661 0.65 6.06 0.48 1.51e-8 Mood instability; TGCT trans rs7618501 0.602 rs10049087 chr3:50123417 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.89 -10.03 -0.67 1.1e-17 Intelligence (multi-trait analysis); TGCT cis rs2066819 0.786 rs111580405 chr12:56739557 A/G cg26714650 chr12:56694279 CS -1.36 -5.95 -0.47 2.56e-8 Psoriasis vulgaris; TGCT cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs9394841 0.692 rs2395795 chr6:41802354 G/A cg08135965 chr6:41755394 TOMM6 0.54 5.04 0.41 1.57e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.88 8.57 0.61 3.38e-14 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs59275611 chr8:58195191 G/A cg21724239 chr8:58056113 NA 0.38 4.79 0.4 4.64e-6 Developmental language disorder (linguistic errors); TGCT cis rs3771570 1.000 rs73002147 chr2:242302934 T/C cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs9303401 0.659 rs17822837 chr17:56737838 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 4.6 0.38 1.03e-5 Cognitive test performance; TGCT cis rs12681287 0.640 rs72606633 chr8:87476236 T/C cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs12682352 0.652 rs3789843 chr8:8724257 C/T cg08975724 chr8:8085496 FLJ10661 0.56 5.13 0.42 1.07e-6 Neuroticism; TGCT cis rs2956278 0.717 rs2956292 chr12:84680026 A/G cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs9790314 0.846 rs6791213 chr3:161033721 A/G cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.9e-8 Morning vs. evening chronotype; TGCT cis rs4766566 0.609 rs933305 chr12:111738287 G/A cg07658449 chr12:111725167 CUX2 0.29 4.77 0.39 4.99e-6 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs11971779 0.838 rs4728468 chr7:139122978 G/A cg07862535 chr7:139043722 LUC7L2 0.71 5.22 0.42 7.33e-7 Diisocyanate-induced asthma; TGCT cis rs225245 0.817 rs1634684 chr17:33941051 A/G cg05299278 chr17:33885742 SLFN14 0.21 4.44 0.37 1.98e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs3617 0.539 rs4687689 chr3:52948674 A/C cg11645453 chr3:52864694 ITIH4 -0.26 -5.03 -0.41 1.68e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs912057 0.560 rs1294416 chr6:6741327 A/G cg06612196 chr6:6737390 NA 0.49 7.31 0.55 2.85e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs2066819 1.000 rs2695782 chr12:56722830 C/T cg26714650 chr12:56694279 CS 1.44 7.08 0.54 9.46e-11 Psoriasis vulgaris; TGCT cis rs8014204 0.762 rs10148293 chr14:75296831 C/T cg06637938 chr14:75390232 RPS6KL1 -0.57 -5.07 -0.41 1.4e-6 Caffeine consumption; TGCT cis rs6951245 0.678 rs4724725 chr7:1214751 G/A cg03188948 chr7:1209495 NA 0.79 6.66 0.51 8.12e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg16414030 chr3:133502952 NA -0.48 -6.64 -0.51 8.96e-10 Iron status biomarkers; TGCT cis rs9549260 0.709 rs12585870 chr13:41199487 A/C cg21288729 chr13:41239152 FOXO1 0.99 10.49 0.69 8.15e-19 Red blood cell count; TGCT cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg19774624 chr17:42201019 HDAC5 -0.81 -9.21 -0.64 1.02e-15 Total body bone mineral density; TGCT cis rs644799 0.544 rs687559 chr11:95598629 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.5 -5.28 -0.43 5.49e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6912958 0.702 rs6906769 chr6:88235949 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs62380364 0.613 rs254781 chr5:88000636 C/T cg24804195 chr5:87968844 LOC645323 -0.58 -5.55 -0.45 1.64e-7 Intelligence (multi-trait analysis); TGCT cis rs7072216 0.763 rs8181292 chr10:100175477 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs36051895 0.632 rs7040806 chr9:5174782 C/T cg02405213 chr9:5042618 JAK2 -0.74 -10.54 -0.69 6.32e-19 Pediatric autoimmune diseases; TGCT cis rs921968 0.540 rs646295 chr2:219408558 A/C cg02176678 chr2:219576539 TTLL4 0.45 6.48 0.5 1.93e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs877282 0.853 rs10904544 chr10:756966 A/G cg17470449 chr10:769945 NA 0.35 5.06 0.41 1.44e-6 Uric acid levels; TGCT cis rs61776719 0.738 rs7555461 chr1:38444749 T/C cg12658694 chr1:38397304 INPP5B -0.55 -5.69 -0.46 8.64e-8 Coronary artery disease; TGCT cis rs11627546 0.615 rs61980618 chr14:70367202 C/G cg10496350 chr14:71275911 MAP3K9 -0.94 -4.44 -0.37 1.96e-5 Red blood cell traits; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg11905131 chr22:24372483 LOC391322 -0.89 -9.98 -0.67 1.39e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.576 rs7660951 chr4:98651581 T/A cg05340658 chr4:99064831 C4orf37 0.48 5.22 0.42 7.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8180040 0.652 rs13077398 chr3:47011120 G/C cg27129171 chr3:47204927 SETD2 0.73 9.42 0.65 3.15e-16 Colorectal cancer; TGCT cis rs11209185 0.509 rs9436791 chr1:68452857 A/C cg22082780 chr1:68452167 NA 0.32 5.05 0.41 1.56e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7014346 0.767 rs7837644 chr8:128423398 A/T cg04263511 chr8:128962092 PVT1 -0.31 -4.5 -0.37 1.54e-5 Colorectal cancer; TGCT cis rs7829975 0.593 rs2979241 chr8:8303353 G/C cg15556689 chr8:8085844 FLJ10661 0.67 6.21 0.49 7.41e-9 Mood instability; TGCT cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg00786635 chr1:25594202 NA 0.59 6.09 0.48 1.34e-8 Erythrocyte sedimentation rate; TGCT cis rs1048238 0.846 rs945420 chr1:16345208 G/A cg21385522 chr1:16154831 NA 0.43 4.52 0.38 1.43e-5 Systolic blood pressure; TGCT trans rs208520 1.000 rs28773210 chr6:66993566 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.47 0.56 1.27e-11 Exhaled nitric oxide output; TGCT cis rs2933343 0.700 rs1683787 chr3:128627021 C/T cg11901034 chr3:128598214 ACAD9 0.63 6.0 0.47 2.01e-8 IgG glycosylation; TGCT cis rs7666738 0.830 rs62321565 chr4:98976571 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg00786635 chr1:25594202 NA 0.55 5.74 0.46 6.91e-8 Erythrocyte sedimentation rate; TGCT cis rs9818758 0.607 rs34823813 chr3:49749976 G/A cg08550065 chr3:50336684 HYAL3;NAT6 1.04 5.12 0.42 1.13e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs17270561 0.779 rs17271767 chr6:25886921 C/T cg17691542 chr6:26056736 HIST1H1C 0.87 6.0 0.47 2.02e-8 Iron status biomarkers; TGCT cis rs1577917 0.958 rs12196175 chr6:86779370 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.86e-7 Response to antipsychotic treatment; TGCT cis rs7223966 1.000 rs7217982 chr17:61832150 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg08125733 chr17:73851984 WBP2 1.17 12.85 0.76 1.47e-24 Psoriasis; TGCT cis rs2836974 0.584 rs6517535 chr21:40653352 G/C cg17971929 chr21:40555470 PSMG1 -0.71 -6.63 -0.51 9.09e-10 Cognitive function; TGCT cis rs7666738 0.830 rs60391193 chr4:98933912 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.623 rs7859286 chr9:5260940 G/T cg02405213 chr9:5042618 JAK2 -0.7 -9.4 -0.65 3.55e-16 Pediatric autoimmune diseases; TGCT cis rs9300255 0.566 rs10744150 chr12:123721614 A/C cg00376283 chr12:123451042 ABCB9 0.79 6.72 0.52 6e-10 Neutrophil percentage of white cells; TGCT cis rs9467773 0.804 rs2073526 chr6:26374658 C/T cg15659132 chr6:26577336 NA -0.48 -4.79 -0.39 4.75e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs9992639 chr4:98940400 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg11861562 chr11:117069780 TAGLN 0.27 4.59 0.38 1.06e-5 Blood protein levels; TGCT cis rs7552404 0.924 rs2173378 chr1:76201992 G/T cg22875332 chr1:76189707 ACADM 0.72 8.9 0.62 5.76e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 0.871 rs56372514 chr8:58157166 A/G cg21724239 chr8:58056113 NA 0.39 5.14 0.42 1.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs4730223 chr7:106814234 A/T cg02696742 chr7:106810147 HBP1 0.77 6.65 0.51 8.18e-10 Coronary artery disease; TGCT cis rs11122272 0.735 rs2749708 chr1:231529610 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT cis rs7432375 0.901 rs7618518 chr3:136370092 C/T cg12473912 chr3:136751656 NA -0.36 -5.06 -0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 8.56 0.61 3.72e-14 Platelet count; TGCT cis rs854765 0.547 rs2955385 chr17:17939247 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.77 8.07 0.59 5.16e-13 Total body bone mineral density; TGCT cis rs2115630 0.902 rs8023276 chr15:85219638 C/T cg11189052 chr15:85197271 WDR73 -0.67 -6.67 -0.51 7.74e-10 P wave terminal force; TGCT cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg18305652 chr10:134549665 INPP5A 0.34 5.64 0.45 1.08e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg20891558 chr2:74357851 NA 0.62 9.22 0.64 9.54e-16 Gestational age at birth (maternal effect); TGCT cis rs7665147 1 rs7665147 chr4:57767327 T/A cg26694713 chr4:57773883 REST 0.72 6.38 0.5 3.19e-9 Platelet count; TGCT cis rs4654899 0.802 rs12127519 chr1:21247365 C/T cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg22442454 chr1:209979470 IRF6 0.59 5.95 0.47 2.52e-8 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs933688 1.000 rs186717 chr5:90780467 T/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.22 0.59 2.36e-13 Smoking behavior; TGCT cis rs2120019 1.000 rs12901243 chr15:75374233 C/T cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs7660520 0.524 rs12643521 chr4:183728242 C/G cg04181038 chr4:183730758 NA 0.68 5.79 0.46 5.38e-8 Pediatric autoimmune diseases; TGCT cis rs597539 0.652 rs579136 chr11:68637476 C/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs12681288 0.862 rs2701898 chr8:1020812 C/T cg08872321 chr8:1308229 NA -0.26 -4.75 -0.39 5.45e-6 Schizophrenia; TGCT cis rs7666738 0.924 rs11097592 chr4:98927532 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.23 0.42 7.12e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9677476 0.909 rs6437010 chr2:232113263 G/C cg07929768 chr2:232055508 NA 0.3 4.48 0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs3806843 0.900 rs2563280 chr5:140131530 G/C cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg01802117 chr1:53393560 SCP2 -0.41 -4.95 -0.41 2.39e-6 Monocyte count; TGCT cis rs6912958 0.559 rs369674 chr6:88043402 C/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.47 -6.33 -0.49 4.08e-9 Monocyte percentage of white cells; TGCT cis rs2688608 0.592 rs13013 chr10:75562161 C/A cg19442545 chr10:75533431 FUT11 -0.36 -5.67 -0.45 9.71e-8 Inflammatory bowel disease; TGCT cis rs28595532 0.920 rs114581578 chr4:119756404 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7192750 0.586 rs62053803 chr16:71989413 G/A cg06353428 chr16:71660113 MARVELD3 0.74 6.6 0.51 1.09e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg08736216 chr1:53307985 ZYG11A 0.29 5.96 0.47 2.43e-8 Monocyte count; TGCT cis rs7677751 0.767 rs6846502 chr4:55062090 T/C cg17187183 chr4:55093834 PDGFRA 0.48 6.38 0.5 3.27e-9 Corneal astigmatism; TGCT cis rs13118159 0.767 rs2141656 chr4:1317192 C/T cg13395646 chr4:1353034 KIAA1530 -0.41 -4.69 -0.39 7.11e-6 Longevity; TGCT cis rs2288884 1.000 rs11673286 chr19:52540318 C/T cg13540795 chr19:52551618 ZNF432 -0.58 -5.03 -0.41 1.67e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs12541335 0.615 rs4872464 chr8:22153381 G/A cg02463440 chr8:22132932 PIWIL2 0.25 4.86 0.4 3.45e-6 Hypertriglyceridemia; TGCT cis rs4713118 0.662 rs9468271 chr6:28024570 A/G cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg12667521 chr19:29218732 NA 0.53 5.63 0.45 1.16e-7 Methadone dose in opioid dependence; TGCT cis rs9653442 0.545 rs4490209 chr2:100766711 C/G cg07810366 chr2:100720526 AFF3 -0.35 -5.18 -0.42 8.67e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10193935 0.901 rs10169971 chr2:42602189 G/A cg27598129 chr2:42591480 NA -0.4 -5.53 -0.44 1.83e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3780378 0.967 rs7852988 chr9:5010751 C/A cg02405213 chr9:5042618 JAK2 -0.56 -7.5 -0.56 1.09e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs12220898 0.749 rs10735220 chr10:50473635 A/G cg06072769 chr10:50146962 WDFY4 0.36 4.67 0.39 7.64e-6 Inflammatory biomarkers; TGCT cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg09323728 chr8:95962352 TP53INP1 -0.54 -6.92 -0.53 2.17e-10 Type 2 diabetes; TGCT cis rs2535633 0.631 rs2581827 chr3:52966558 C/T cg10802521 chr3:52805072 NEK4 0.57 5.93 0.47 2.8e-8 Body mass index; TGCT cis rs1865760 1.000 rs7757666 chr6:25902626 T/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs875971 0.862 rs2901152 chr7:65765004 G/A cg11764359 chr7:65958608 NA -0.54 -4.81 -0.4 4.32e-6 Aortic root size; TGCT cis rs60843830 1.000 rs55936726 chr2:258210 T/C cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.78 0.57 2.42e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs4663866 1.000 rs13033501 chr2:239181860 G/A cg17283117 chr2:239148619 HES6 1.0 4.6 0.38 1.03e-5 Irritable bowel syndrome; TGCT cis rs2439831 0.867 rs28415933 chr15:43635800 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs4253772 0.550 rs9615913 chr22:46668515 A/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.57 -4.45 -0.37 1.86e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs2549003 1.000 rs10068129 chr5:131821246 A/G cg00255919 chr5:131827918 IRF1 -0.2 -4.56 -0.38 1.23e-5 Asthma (sex interaction); TGCT cis rs7909074 1.000 rs12777258 chr10:45394961 A/G cg05187965 chr10:45406764 TMEM72 0.25 5.43 0.44 2.8e-7 Mean corpuscular volume; TGCT cis rs709400 0.593 rs12898029 chr14:103877884 T/C cg12935359 chr14:103987150 CKB 0.34 5.17 0.42 9.21e-7 Body mass index; TGCT cis rs28595532 0.920 rs114796605 chr4:119744472 C/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs11190604 0.767 rs10883479 chr10:102162860 A/G cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6831352 0.918 rs29001203 chr4:100053091 A/G cg12011299 chr4:100065546 ADH4 -0.42 -5.12 -0.42 1.14e-6 Alcohol dependence; TGCT cis rs896854 0.714 rs572547 chr8:95966286 A/G cg16049864 chr8:95962084 TP53INP1 0.64 7.66 0.57 4.51e-12 Type 2 diabetes; TGCT cis rs644799 0.662 rs35793328 chr11:95490896 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.77 8.04 0.59 6.16e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11585357 0.895 rs72633823 chr1:17630779 G/A cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs6547741 0.967 rs4665996 chr2:27814343 T/C cg27432699 chr2:27873401 GPN1 0.18 4.65 0.38 8.53e-6 Oral cavity cancer; TGCT cis rs5769765 0.908 rs138866 chr22:50205903 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.36 -5.69 -0.46 8.66e-8 Schizophrenia; TGCT cis rs17345786 0.861 rs17402964 chr3:101067945 C/T cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.21 -0.59 2.39e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs6674176 0.597 rs3762422 chr1:44400532 T/A cg13606994 chr1:44402422 ARTN -0.49 -5.4 -0.44 3.31e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg18230493 chr5:56204884 C5orf35 -0.63 -5.58 -0.45 1.47e-7 Initial pursuit acceleration; TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.97 0.41 2.21e-6 Prudent dietary pattern; TGCT cis rs7772486 0.720 rs6570713 chr6:146075085 G/A cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs941873 0.805 rs8837 chr10:81114813 C/G cg09469691 chr10:81107165 PPIF 0.5 4.96 0.41 2.27e-6 Height; TGCT cis rs1218582 0.772 rs2174507 chr1:154887949 C/T cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs6840360 0.615 rs6535822 chr4:152679722 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.16 -0.42 9.49e-7 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg10047753 chr17:41438598 NA 0.97 9.74 0.66 5.32e-17 Menopause (age at onset); TGCT cis rs6463523 0.933 rs6974151 chr7:758269 T/C cg06242242 chr7:766104 PRKAR1B;HEATR2 0.86 11.91 0.73 2.85e-22 Subjective well-being; TGCT cis rs28595532 0.920 rs55758547 chr4:119769475 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs13064411 0.696 rs9814395 chr3:113188885 C/T cg18753928 chr3:113234510 CCDC52 -0.67 -5.46 -0.44 2.45e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs6835098 0.692 rs6553679 chr4:174072292 C/T cg08422745 chr4:174089978 GALNT7 -0.77 -8.6 -0.61 2.87e-14 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7020830 0.861 rs13289001 chr9:37311592 A/G cg14294708 chr9:37120828 ZCCHC7 1.28 18.22 0.85 7.33e-37 Schizophrenia; TGCT cis rs453301 0.658 rs9650616 chr8:8869199 T/G cg06636001 chr8:8085503 FLJ10661 -0.68 -5.62 -0.45 1.21e-7 Joint mobility (Beighton score); TGCT cis rs10791097 0.667 rs4937585 chr11:130741940 A/G cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg22166914 chr1:53195759 ZYG11B 0.37 5.95 0.47 2.57e-8 Monocyte count; TGCT cis rs9733 0.566 rs11204675 chr1:150570985 A/C cg13175981 chr1:150552382 MCL1 0.56 6.41 0.5 2.8e-9 Tonsillectomy; TGCT cis rs9634489 0.502 rs77248334 chr13:97119162 T/G cg11411106 chr13:97107445 HS6ST3 0.27 4.72 0.39 6.26e-6 Body mass index; TGCT cis rs3733585 0.605 rs4697926 chr4:10124567 G/T cg00071950 chr4:10020882 SLC2A9 0.49 5.1 0.42 1.23e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2153535 0.601 rs9505473 chr6:8538777 T/C cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10858047 0.700 rs7538880 chr1:115194374 G/A cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs2777491 1.000 rs316605 chr15:41771591 G/A cg18705301 chr15:41695430 NDUFAF1 -0.76 -11.32 -0.71 7.77e-21 Ulcerative colitis; TGCT cis rs8070740 0.898 rs4493114 chr17:5324207 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.77 0.39 5.14e-6 Menopause (age at onset); TGCT cis rs9916302 0.731 rs11868030 chr17:37650332 A/G cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs9926296 0.643 rs2159114 chr16:89831841 A/G cg27121462 chr16:89883253 FANCA 0.57 5.38 0.43 3.64e-7 Vitiligo; TGCT cis rs2463822 1.000 rs72921498 chr11:62113090 C/T cg06239285 chr11:62104954 ASRGL1 -0.92 -6.76 -0.52 4.71e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT trans rs7824557 0.564 rs2736295 chr8:11234780 C/G cg15556689 chr8:8085844 FLJ10661 0.72 6.62 0.51 9.66e-10 Retinal vascular caliber; TGCT cis rs7666738 0.791 rs6840669 chr4:99016020 G/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4595586 0.563 rs11169769 chr12:39233134 C/G cg26384229 chr12:38710491 ALG10B 0.65 5.29 0.43 5.43e-7 Morning vs. evening chronotype; TGCT cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg25767906 chr1:53392781 SCP2 0.44 4.84 0.4 3.8e-6 Monocyte count; TGCT cis rs5769707 0.967 rs9616701 chr22:50025546 G/A cg05373962 chr22:49881684 NA -0.31 -6.42 -0.5 2.6e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs644799 0.710 rs3017756 chr11:95537358 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.5 0.61 5.03e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9858542 0.543 rs2230929 chr3:49343175 G/A cg00383909 chr3:49044727 WDR6 0.65 4.46 0.37 1.83e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs12464483 0.524 rs4952172 chr2:30888286 A/G cg12454169 chr2:30669597 LCLAT1 -0.41 -4.47 -0.37 1.73e-5 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs12142240 0.698 rs72679807 chr1:46846490 G/A cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs933688 1.000 rs1895448 chr5:90743854 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.93 8.3 0.6 1.46e-13 Smoking behavior; TGCT trans rs1005277 0.540 rs1987431 chr10:37988887 T/C cg17830980 chr10:43048298 ZNF37B -0.65 -7.3 -0.55 2.95e-11 Extrinsic epigenetic age acceleration; TGCT cis rs7924176 0.521 rs11000959 chr10:76046811 C/G cg19889307 chr10:75911429 ADK;AP3M1 -0.47 -4.46 -0.37 1.84e-5 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs765787 0.530 rs4775822 chr15:45527127 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.75e-7 Uric acid levels; TGCT cis rs2742417 0.603 rs2742458 chr3:45767602 C/T cg04837898 chr3:45731254 SACM1L -0.65 -6.95 -0.53 1.84e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs35160687 0.842 rs1863052 chr2:86559358 A/G cg03171300 chr2:86307199 POLR1A 0.27 4.69 0.39 6.99e-6 Night sleep phenotypes; TGCT cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.03 8.57 0.61 3.5e-14 Platelet count; TGCT cis rs2070488 0.775 rs7647657 chr3:38573746 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.62 -5.32 -0.43 4.71e-7 Electrocardiographic conduction measures; TGCT cis rs7260538 0.773 rs2200238 chr19:41527265 G/A cg27089200 chr19:41531976 NA 0.43 5.32 0.43 4.75e-7 DDT metabolite (p,p'-DDE levels); TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg16325326 chr1:53192061 ZYG11B 0.56 6.12 0.48 1.15e-8 Monocyte count; TGCT cis rs6969780 0.630 rs3735530 chr7:27189982 C/T cg04321618 chr7:27170880 HOXA4 -0.52 -5.18 -0.42 8.67e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2153535 0.580 rs1414342 chr6:8462552 A/G cg23788917 chr6:8435910 SLC35B3 0.62 5.58 0.45 1.44e-7 Motion sickness; TGCT trans rs1005277 0.579 rs2505196 chr10:38393563 G/A cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs9312648 1.000 rs9312648 chr4:55241581 C/T cg22115196 chr4:54829461 NA -0.26 -4.51 -0.38 1.46e-5 Response to amphetamines; TGCT cis rs3784262 1.000 rs4646619 chr15:58258342 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.7 -0.57 3.78e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2486288 0.656 rs11637838 chr15:45550657 A/G cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.34 -0.43 4.26e-7 Glomerular filtration rate; TGCT cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs1941184 0.500 rs1460598 chr18:29028491 G/A cg14871544 chr18:29027885 DSG3 0.43 4.51 0.38 1.47e-5 Parkinson's disease (age of onset); TGCT cis rs17221829 0.699 rs7129641 chr11:89383706 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.44 -0.37 1.96e-5 Anxiety in major depressive disorder; TGCT trans rs17685 0.712 rs10235738 chr7:75773460 G/A cg19862616 chr7:65841803 NCRNA00174 0.53 9.19 0.64 1.13e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs4372836 1.000 rs4640348 chr2:28965479 T/C cg09522027 chr2:28974177 PPP1CB -0.54 -4.68 -0.39 7.33e-6 Body mass index; TGCT cis rs7833790 0.724 rs6473309 chr8:82707880 A/G cg06027949 chr8:82754900 SNX16 -0.66 -5.09 -0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs2637266 0.967 rs12244619 chr10:78352502 C/T cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.79e-6 Pulmonary function; TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg26354017 chr1:205819088 PM20D1 0.57 7.08 0.54 9.44e-11 Menarche (age at onset); TGCT cis rs10940138 0.779 rs991123 chr5:67246171 G/A ch.5.1281357F chr5:67228439 NA 0.41 4.76 0.39 5.34e-6 Menarche (age at onset); TGCT cis rs55665837 0.583 rs78843135 chr11:14411254 T/G cg19336497 chr11:14380999 RRAS2 -0.3 -4.61 -0.38 9.73e-6 Vitamin D levels; TGCT trans rs1814175 0.527 rs10769595 chr11:49638212 A/G cg11707556 chr5:10655725 ANKRD33B -0.4 -8.19 -0.59 2.67e-13 Height; TGCT cis rs10883723 0.810 rs17782574 chr10:104279394 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs595982 0.702 rs638050 chr19:49375676 A/G cg15549821 chr19:49342101 PLEKHA4 -0.37 -5.07 -0.41 1.4e-6 Red cell distribution width; TGCT cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg03806693 chr22:41940476 POLR3H -1.14 -13.38 -0.77 8.05e-26 Vitiligo; TGCT cis rs7542091 0.635 rs985431 chr1:210043948 A/T cg00989853 chr1:209979345 IRF6 0.43 4.58 0.38 1.12e-5 Monobrow; TGCT cis rs60843830 0.596 rs17041320 chr2:112051 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.53 4.69 0.39 7.12e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg03161606 chr19:29218774 NA 0.58 6.44 0.5 2.4e-9 Methadone dose in opioid dependence; TGCT cis rs28595532 0.748 rs72670246 chr4:119335061 G/A cg21605333 chr4:119757512 SEC24D 0.83 5.05 0.41 1.55e-6 Cannabis dependence symptom count; TGCT cis rs6598955 0.724 rs12096059 chr1:26596709 G/A cg04990556 chr1:26633338 UBXN11 -0.91 -11.45 -0.72 3.65e-21 Obesity-related traits; TGCT cis rs10782582 0.593 rs11802717 chr1:76124648 C/T cg22875332 chr1:76189707 ACADM -0.54 -6.36 -0.5 3.61e-9 Daytime sleep phenotypes; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs7223966 1.000 rs11654335 chr17:61797579 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.7 0.39 6.69e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs11030122 0.702 rs10767715 chr11:3951409 G/T cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs11031096 0.503 rs67065286 chr11:4105273 A/C cg18678763 chr11:4115507 RRM1 -0.47 -5.66 -0.45 9.94e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9914544 0.564 rs1859083 chr17:18843306 C/T cg26306683 chr17:18585705 ZNF286B -0.52 -4.79 -0.4 4.66e-6 Educational attainment (years of education); TGCT cis rs9527 0.590 rs1046411 chr10:104837816 G/A cg04362960 chr10:104952993 NT5C2 0.63 5.44 0.44 2.74e-7 Arsenic metabolism; TGCT cis rs1577917 1.000 rs34852683 chr6:86702330 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs2842992 0.872 rs2758328 chr6:160090731 T/A cg11366901 chr6:160182831 ACAT2 0.96 6.28 0.49 5.21e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs16958440 0.867 rs79078752 chr18:44667462 A/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs11771526 0.901 rs34376799 chr7:32316932 T/C cg27532318 chr7:32358331 NA 0.57 4.49 0.37 1.61e-5 Body mass index; TGCT cis rs10791097 0.642 rs7107568 chr11:130779668 T/C cg05962950 chr11:130786565 SNX19 0.89 10.79 0.7 1.51e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2836974 0.897 rs13047678 chr21:40708853 C/T cg17971929 chr21:40555470 PSMG1 0.92 7.86 0.58 1.58e-12 Cognitive function; TGCT cis rs3087591 0.922 rs12950236 chr17:29431034 A/G cg24425628 chr17:29625626 OMG;NF1 0.46 7.15 0.54 6.63e-11 Hip circumference; TGCT cis rs539096 0.692 rs6669157 chr1:44216876 T/C cg12908607 chr1:44402522 ARTN -0.63 -7.47 -0.56 1.25e-11 Intelligence (multi-trait analysis); TGCT cis rs13318932 0.505 rs12108018 chr3:98650393 C/G cg27410952 chr3:98620265 DCBLD2 -0.94 -4.71 -0.39 6.64e-6 Blood protein levels; TGCT cis rs477895 0.713 rs1059440 chr11:63991801 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.86 -7.04 -0.53 1.17e-10 Mean platelet volume; TGCT cis rs986417 1.000 rs1254324 chr14:60908551 C/T cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs7726839 0.540 rs11750321 chr5:599196 C/T cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs2361718 0.521 rs2361724 chr17:78099114 G/A cg27614120 chr17:77386099 HRNBP3 0.28 5.0 0.41 1.93e-6 Yeast infection; TGCT cis rs35146811 0.735 rs1636975 chr7:99812089 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs10507380 0.654 rs74695290 chr13:27923224 T/C cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg25767906 chr1:53392781 SCP2 -0.51 -6.01 -0.47 1.93e-8 Monocyte count; TGCT cis rs9906944 0.703 rs940088 chr17:47145848 T/C cg07075026 chr17:47091521 IGF2BP1 -0.45 -4.81 -0.4 4.38e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs3749237 0.595 rs4955412 chr3:49418168 A/C cg02487422 chr3:49467188 NICN1 0.59 6.01 0.47 1.92e-8 Resting heart rate; TGCT cis rs6496667 0.600 rs62019401 chr15:91071855 C/T cg22089800 chr15:90895588 ZNF774 0.63 4.5 0.37 1.53e-5 Rheumatoid arthritis; TGCT cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg07507251 chr3:52567010 NT5DC2 0.5 7.29 0.55 3.14e-11 Electroencephalogram traits; TGCT cis rs7646507 0.536 rs9857402 chr3:172559793 A/G cg10532262 chr3:172428426 NCEH1 -0.82 -4.44 -0.37 1.99e-5 Obesity-related traits; TGCT cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg22618164 chr12:122356400 WDR66 -0.55 -5.56 -0.45 1.57e-7 Mean corpuscular volume; TGCT cis rs9328448 0.882 rs9502671 chr6:7981808 G/A cg13863638 chr6:7199401 RREB1 0.19 4.49 0.37 1.64e-5 Coronary artery calcification; TGCT cis rs4845570 0.850 rs11204892 chr1:151768048 A/G cg07092448 chr1:151763213 TDRKH 1.07 9.04 0.63 2.62e-15 Coronary artery disease; TGCT cis rs60843830 1.000 rs2290911 chr2:224919 A/G cg00108164 chr2:264199 ACP1;SH3YL1 0.74 6.83 0.52 3.3e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs11112613 0.775 rs10507194 chr12:105959488 G/A cg03607813 chr12:105948248 NA 0.47 5.74 0.46 6.71e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7954584 0.813 rs11043288 chr12:122451187 C/T cg21171335 chr12:122356390 WDR66 -0.54 -5.43 -0.44 2.85e-7 Mean corpuscular volume; TGCT cis rs2115630 0.754 rs12595321 chr15:85331269 G/A cg11189052 chr15:85197271 WDR73 -0.56 -4.86 -0.4 3.41e-6 P wave terminal force; TGCT cis rs7959452 0.640 rs11177599 chr12:69721970 G/A cg11871910 chr12:69753446 YEATS4 0.63 6.4 0.5 2.88e-9 Blood protein levels; TGCT cis rs7267979 1.000 rs2474777 chr20:25272633 A/G cg03522245 chr20:25566470 NINL 0.62 6.67 0.51 7.51e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6429082 0.807 rs4659857 chr1:235581411 C/T cg26050004 chr1:235667680 B3GALNT2 -0.57 -5.03 -0.41 1.7e-6 Adiposity; TGCT cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg05738196 chr6:26577821 NA 0.86 10.49 0.69 8.31e-19 Intelligence (multi-trait analysis); TGCT cis rs4253772 0.550 rs12165597 chr22:46705584 A/G cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9894429 0.816 rs9747093 chr17:79584280 G/A cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs6089584 0.888 rs6089623 chr20:60615759 A/G cg13770153 chr20:60521292 NA -0.54 -7.13 -0.54 7.45e-11 Body mass index; TGCT cis rs7267979 1.000 rs6115159 chr20:25350944 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3749237 0.595 rs12489092 chr3:49550914 G/C cg03060546 chr3:49711283 APEH 0.75 8.62 0.61 2.66e-14 Resting heart rate; TGCT cis rs710216 0.917 rs2297977 chr1:43415288 G/T cg03128534 chr1:43423976 SLC2A1 0.57 4.58 0.38 1.1e-5 Red cell distribution width; TGCT cis rs9443645 0.810 rs9448607 chr6:79715620 G/A cg09184832 chr6:79620586 NA -0.43 -4.83 -0.4 3.93e-6 Intelligence (multi-trait analysis); TGCT cis rs6674176 0.628 rs12145999 chr1:44428632 C/T cg13606994 chr1:44402422 ARTN -0.46 -4.98 -0.41 2.12e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9486715 0.825 rs211158 chr6:97022938 C/G cg18709589 chr6:96969512 KIAA0776 -0.85 -8.16 -0.59 3.2e-13 Headache; TGCT trans rs1814175 0.791 rs10769593 chr11:49616217 T/C cg11707556 chr5:10655725 ANKRD33B -0.38 -7.65 -0.57 4.76e-12 Height; TGCT cis rs9868809 0.881 rs6773261 chr3:48675064 A/G cg00383909 chr3:49044727 WDR6 0.95 5.29 0.43 5.34e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs6088590 0.561 rs6059934 chr20:33178324 G/T cg08999081 chr20:33150536 PIGU 0.25 4.73 0.39 5.91e-6 Coronary artery disease; TGCT cis rs8017423 0.967 rs4900033 chr14:90701963 C/A cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs12477438 0.501 rs9941561 chr2:99753829 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs4788570 0.566 rs16972808 chr16:71478717 A/G cg06353428 chr16:71660113 MARVELD3 -1.32 -7.86 -0.58 1.6e-12 Intelligence (multi-trait analysis); TGCT cis rs12711979 0.509 rs10192699 chr2:3824297 A/G cg17052675 chr2:3827356 NA -0.55 -12.72 -0.75 3.04e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7937682 0.883 rs2212520 chr11:111462096 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs6570726 0.764 rs4263604 chr6:145916697 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.71e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2074038 1.000 rs2074038 chr11:44087989 G/T cg17479956 chr11:44115929 EXT2 0.35 5.09 0.42 1.27e-6 IgA nephropathy; TGCT cis rs9534288 0.763 rs7989605 chr13:46534036 G/A cg15192986 chr13:46630673 CPB2 -0.51 -7.28 -0.55 3.34e-11 Blood protein levels; TGCT cis rs13108904 0.517 rs13128825 chr4:1334007 G/A cg13395646 chr4:1353034 KIAA1530 -0.55 -7.57 -0.56 7.56e-12 Obesity-related traits; TGCT cis rs10984561 0.881 rs10984555 chr9:122247683 T/C cg14242995 chr9:122249943 NA 0.75 6.41 0.5 2.7e-9 Pulmonary function decline; TGCT cis rs10986311 0.928 rs4836973 chr9:127091587 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 0.2 4.59 0.38 1.05e-5 Vitiligo; TGCT cis rs7208859 0.573 rs73277974 chr17:29189869 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs240764 0.853 rs12206945 chr6:101018032 C/T cg21058520 chr6:100914733 NA -0.35 -4.51 -0.38 1.49e-5 Neuroticism; TGCT cis rs6964587 0.967 rs9656003 chr7:91766322 A/C cg17063962 chr7:91808500 NA 0.91 9.8 0.66 3.89e-17 Breast cancer; TGCT cis rs9393777 0.546 rs9366673 chr6:26893329 C/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.6 -4.79 -0.4 4.67e-6 Intelligence (multi-trait analysis); TGCT cis rs877282 0.891 rs11599917 chr10:762288 G/A cg17470449 chr10:769945 NA 0.35 5.23 0.43 7e-7 Uric acid levels; TGCT cis rs7100689 0.646 rs1953972 chr10:82145666 A/G cg01528321 chr10:82214614 TSPAN14 0.78 7.86 0.58 1.56e-12 Post bronchodilator FEV1; TGCT cis rs711830 1.000 rs1051929 chr2:177036754 T/C cg13092806 chr2:177043255 NA 0.74 5.95 0.47 2.58e-8 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg03609598 chr5:56110824 MAP3K1 -0.59 -4.74 -0.39 5.8e-6 Type 2 diabetes; TGCT cis rs2180341 1.000 rs2057223 chr6:127637374 T/C cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs2688482 0.512 rs1104760 chr3:195517321 G/A cg13752114 chr3:195489708 MUC4 0.32 4.72 0.39 6.34e-6 Lung disease severity in cystic fibrosis; TGCT cis rs1891498 0.560 rs35594137 chr1:147245497 C/T cg17941330 chr1:147245494 GJA5 0.36 4.76 0.39 5.28e-6 Cognitive performance; TGCT cis rs4819052 0.851 rs13052344 chr21:46676101 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7727544 0.904 rs6897575 chr5:131604535 C/T cg24060327 chr5:131705240 SLC22A5 -0.6 -6.4 -0.5 2.87e-9 Blood metabolite levels; TGCT cis rs2404602 0.735 rs1607015 chr15:76702429 C/T cg22467129 chr15:76604101 ETFA 0.52 5.5 0.44 2.05e-7 Blood metabolite levels; TGCT cis rs2239547 0.563 rs6445547 chr3:52908577 T/C cg11645453 chr3:52864694 ITIH4 0.34 5.72 0.46 7.68e-8 Schizophrenia; TGCT cis rs7178572 0.568 rs11632966 chr15:77621805 A/C cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs559406 0.623 rs674222 chr18:12848349 G/C cg23598886 chr18:12777645 NA 0.38 4.53 0.38 1.36e-5 Psoriasis; TGCT cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6840360 0.582 rs2724553 chr4:152321881 T/C cg17479576 chr4:152424074 FAM160A1 -0.53 -5.35 -0.43 4.05e-7 Intelligence (multi-trait analysis); TGCT cis rs34014631 1.000 rs17698831 chr10:103656466 T/A cg22630918 chr10:102748988 C10orf2 0.42 4.82 0.4 4.15e-6 Coronary artery calcification; TGCT cis rs11690935 0.959 rs10174525 chr2:172635697 T/C cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg06238570 chr21:40685208 BRWD1 0.69 6.38 0.5 3.25e-9 Cognitive function; TGCT cis rs7119038 0.818 rs10892293 chr11:118665575 A/T cg19308663 chr11:118741387 NA 0.37 5.73 0.46 7.3e-8 Sjögren's syndrome; TGCT cis rs9549367 0.865 rs9549366 chr13:113907644 G/A cg00898013 chr13:113819073 PROZ -0.43 -5.55 -0.45 1.68e-7 Platelet distribution width; TGCT cis rs9467773 0.967 rs1056347 chr6:26527524 G/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg09436375 chr6:42928200 GNMT 0.37 5.21 0.42 7.55e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs950169 0.922 rs12912934 chr15:85114447 C/T cg11189052 chr15:85197271 WDR73 0.77 6.44 0.5 2.34e-9 Schizophrenia; TGCT cis rs3862030 0.533 rs715440 chr10:104258095 A/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -4.99 -0.41 2.01e-6 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs57221529 0.709 rs72707023 chr5:667620 G/A cg20362242 chr5:692897 TPPP 0.53 4.85 0.4 3.56e-6 Lung disease severity in cystic fibrosis; TGCT cis rs6121246 0.609 rs4453755 chr20:30331047 G/A cg10886678 chr20:30946050 ASXL1 -0.52 -4.44 -0.37 1.97e-5 Mean corpuscular hemoglobin; TGCT cis rs11671005 0.735 rs34152946 chr19:58923263 C/T cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT trans rs6089829 0.889 rs6062773 chr20:61663262 G/C cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs11585357 0.843 rs72646796 chr1:17612503 T/C cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs35146811 0.735 rs11764176 chr7:99786964 G/T cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs2836974 0.666 rs12626405 chr21:40663121 G/T cg11644478 chr21:40555479 PSMG1 -0.62 -5.76 -0.46 6.13e-8 Cognitive function; TGCT cis rs4727027 0.933 rs28767030 chr7:148825918 T/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9790314 0.765 rs4856768 chr3:161004392 G/A cg03342759 chr3:160939853 NMD3 -0.47 -5.09 -0.42 1.29e-6 Morning vs. evening chronotype; TGCT cis rs10193935 0.792 rs10204778 chr2:42498121 G/T cg27598129 chr2:42591480 NA -0.42 -5.7 -0.46 8.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7552404 0.924 rs1146580 chr1:76209935 T/C cg22875332 chr1:76189707 ACADM 0.72 8.9 0.62 5.76e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs2235642 0.928 rs2076435 chr16:1607574 C/T cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.26 -0.43 6.24e-7 Coronary artery disease; TGCT cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg02187348 chr16:89574699 SPG7 0.6 6.51 0.5 1.71e-9 Multiple myeloma (IgH translocation); TGCT cis rs2692947 0.673 rs3111873 chr2:96781986 G/C cg23100626 chr2:96804247 ASTL -0.42 -4.97 -0.41 2.18e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs35306767 0.951 rs55742421 chr10:961037 A/C cg20503657 chr10:835505 NA 0.74 10.28 0.68 2.58e-18 Eosinophil percentage of granulocytes; TGCT cis rs801193 0.569 rs35070132 chr7:66238083 C/T cg11764359 chr7:65958608 NA 0.53 4.64 0.38 8.62e-6 Aortic root size; TGCT cis rs875971 1.000 rs7789554 chr7:65946038 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs6448317 0.954 rs13116026 chr4:24922242 T/A cg21108841 chr4:24914750 CCDC149 -0.62 -4.72 -0.39 6.25e-6 Heschl's gyrus morphology; TGCT cis rs1524927 1.000 rs12704873 chr7:96336279 G/C cg03808172 chr7:96339361 SHFM1 0.49 5.06 0.41 1.45e-6 Total body bone mineral density; TGCT cis rs9549367 0.664 rs3794419 chr13:113851874 T/C cg09473364 chr13:112927190 NA -0.32 -5.08 -0.41 1.38e-6 Platelet distribution width; TGCT cis rs7937682 0.575 rs1940391 chr11:111776891 G/A cg09085632 chr11:111637200 PPP2R1B 0.97 10.03 0.67 1.06e-17 Primary sclerosing cholangitis; TGCT cis rs1552244 0.882 rs28366039 chr3:10028988 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.56 -0.51 1.31e-9 Alzheimer's disease; TGCT cis rs9534288 0.716 rs2573304 chr13:46514642 C/T cg15192986 chr13:46630673 CPB2 0.52 6.95 0.53 1.87e-10 Blood protein levels; TGCT cis rs1062177 1.000 rs2964612 chr5:151198750 G/A cg12924095 chr5:151150029 G3BP1 0.35 5.05 0.41 1.53e-6 Preschool internalizing problems; TGCT cis rs1971762 0.527 rs784562 chr12:53919700 A/C cg16917193 chr12:54089295 NA -1.0 -10.24 -0.68 3.39e-18 Height; TGCT trans rs8073060 0.586 rs9649 chr17:34050934 C/T cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg17554472 chr22:41940697 POLR3H -0.47 -4.79 -0.4 4.68e-6 Vitiligo; TGCT cis rs933688 1.000 rs6869717 chr5:90694797 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.91e-14 Smoking behavior; TGCT cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs9611565 0.506 rs1984839 chr22:41685937 G/C cg13695892 chr22:41940480 POLR3H -0.67 -6.23 -0.49 6.73e-9 Vitiligo; TGCT cis rs1451375 0.785 rs6593010 chr7:50629888 A/G cg18232548 chr7:50535776 DDC 0.45 7.11 0.54 8.09e-11 Malaria; TGCT cis rs4819052 0.851 rs7276103 chr21:46666078 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.72 6.39 0.5 3.12e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6733011 0.542 rs6542860 chr2:99679376 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.52 -0.38 1.4e-5 Bipolar disorder; TGCT cis rs7010267 1.000 rs7010267 chr8:119946656 A/C cg17171407 chr8:119960777 TNFRSF11B 0.32 6.24 0.49 6.25e-9 Total body bone mineral density (age 45-60); TGCT cis rs473651 0.716 rs548179 chr2:239320505 G/A cg21699342 chr2:239360505 ASB1 0.19 5.19 0.42 8.4e-7 Multiple system atrophy; TGCT cis rs7940866 0.903 rs10791112 chr11:130870215 A/C cg05962950 chr11:130786565 SNX19 -0.67 -7.04 -0.53 1.19e-10 Schizophrenia; TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg22166914 chr1:53195759 ZYG11B 0.37 6.41 0.5 2.77e-9 Monocyte count; TGCT cis rs1552244 0.572 rs3774208 chr3:10164722 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs3796352 1.000 rs17052727 chr3:53070914 T/C cg07884673 chr3:53033167 SFMBT1 0.57 5.98 0.47 2.16e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6912958 0.754 rs6918909 chr6:88247251 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.07 -0.41 1.41e-6 Monocyte percentage of white cells; TGCT cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg03188948 chr7:1209495 NA 0.44 5.79 0.46 5.49e-8 Longevity;Endometriosis; TGCT cis rs9916302 0.904 rs10221223 chr17:37489100 T/G cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs17376456 0.877 rs7734897 chr5:93305402 G/A cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs78456975 0.527 rs11901028 chr2:1557972 A/G cg01028140 chr2:1542097 TPO -0.33 -5.12 -0.42 1.14e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg13866156 chr1:1669148 SLC35E2 -0.22 -5.23 -0.42 7.06e-7 Body mass index; TGCT cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg12310025 chr6:25882481 NA 0.62 6.5 0.5 1.78e-9 Blood metabolite levels; TGCT cis rs9916302 0.904 rs4794814 chr17:37696852 G/A cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs6430585 0.591 rs77096272 chr2:136663605 C/A cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs789859 0.611 rs1077729 chr3:194418126 A/G cg21106136 chr3:194405973 FAM43A 0.37 4.79 0.39 4.75e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs10493773 0.609 rs12097932 chr1:86182216 A/G cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs6831352 0.918 rs2851249 chr4:100044822 T/C cg12011299 chr4:100065546 ADH4 0.44 5.08 0.42 1.34e-6 Alcohol dependence; TGCT cis rs9527 0.590 rs10786738 chr10:104869451 C/T cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs9814567 0.731 rs34797591 chr3:134192516 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.85 6.71 0.52 6.04e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs208520 0.837 rs208489 chr6:66927584 G/A cg07460842 chr6:66804631 NA -0.94 -9.3 -0.64 6.32e-16 Exhaled nitric oxide output; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg10150615 chr22:24372951 LOC391322 1.01 13.29 0.77 1.32e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs36051895 0.623 rs11506293 chr9:5257430 A/G cg02405213 chr9:5042618 JAK2 -0.69 -8.19 -0.59 2.68e-13 Pediatric autoimmune diseases; TGCT cis rs797680 0.856 rs6682670 chr1:93649732 A/G cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.89e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7819412 0.811 rs2409691 chr8:10943276 C/T cg21775007 chr8:11205619 TDH -0.51 -4.94 -0.41 2.46e-6 Triglycerides; TGCT cis rs11969893 0.850 rs9390697 chr6:101294431 G/A cg12253828 chr6:101329408 ASCC3 1.37 6.33 0.49 4.13e-9 Economic and political preferences (immigration/crime); TGCT cis rs8017423 0.874 rs4900029 chr14:90686257 T/A cg04374321 chr14:90722782 PSMC1 0.77 7.93 0.58 1.12e-12 Mortality in heart failure; TGCT cis rs9467711 0.517 rs16901784 chr6:26555433 C/A cg16898833 chr6:26189333 HIST1H4D 1.1 5.65 0.45 1.05e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9291683 0.530 rs35908990 chr4:9976105 G/A cg00071950 chr4:10020882 SLC2A9 0.65 8.23 0.59 2.21e-13 Bone mineral density; TGCT cis rs72615157 0.539 rs4729575 chr7:99686873 G/T cg13334819 chr7:99746414 C7orf59 0.58 4.49 0.37 1.61e-5 Lung function (FEV1/FVC); TGCT cis rs7617773 0.743 rs11715876 chr3:48377922 G/A cg11946769 chr3:48343235 NME6 0.82 6.99 0.53 1.49e-10 Coronary artery disease; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs916888 0.773 rs199535 chr17:44822662 A/G cg16228356 chr17:43848958 NA -0.27 -4.68 -0.39 7.42e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2710247 1 rs2710247 chr2:219467508 A/G cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10465746 0.809 rs2389617 chr1:84437652 A/T cg10977910 chr1:84465055 TTLL7 0.69 7.1 0.54 8.59e-11 Obesity-related traits; TGCT trans rs7221878 1.000 rs7210540 chr17:36188882 T/C cg03614664 chr22:41346948 RBX1 1.39 6.64 0.51 8.97e-10 Macrophage inflammatory protein 1b levels; TGCT cis rs1483890 0.605 rs1843045 chr3:69413121 C/T cg22125112 chr3:69402811 FRMD4B 0.28 4.68 0.39 7.47e-6 Resting heart rate; TGCT cis rs7772486 0.875 rs2777481 chr6:146310036 G/T cg23711669 chr6:146136114 FBXO30 0.86 9.13 0.63 1.59e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 0.920 rs116634064 chr4:119736514 C/T cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs10876993 0.893 rs3825078 chr12:58089413 A/T cg15848620 chr12:58087721 OS9 -0.73 -5.95 -0.47 2.56e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7845219 0.525 rs6471501 chr8:95922491 A/G cg09323728 chr8:95962352 TP53INP1 -0.41 -4.57 -0.38 1.17e-5 Type 2 diabetes; TGCT cis rs4595586 0.545 rs6580892 chr12:39370237 G/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs9902453 0.845 rs12452201 chr17:28214173 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 7.07 0.54 9.76e-11 Coffee consumption (cups per day); TGCT cis rs453301 0.606 rs6601279 chr8:8908231 G/A cg08975724 chr8:8085496 FLJ10661 -0.58 -4.75 -0.39 5.63e-6 Joint mobility (Beighton score); TGCT cis rs1005277 0.579 rs2474584 chr10:38416389 C/T cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs17221829 0.965 rs10830368 chr11:89459706 C/T cg02982614 chr11:89391479 FOLH1B -0.27 -4.76 -0.39 5.25e-6 Anxiety in major depressive disorder; TGCT cis rs7584330 0.518 rs11884238 chr2:238424671 T/G cg08992911 chr2:238395768 MLPH 0.73 5.01 0.41 1.85e-6 Prostate cancer; TGCT cis rs2288884 0.767 rs17835716 chr19:52551042 A/G cg15405931 chr19:52693188 PPP2R1A -0.64 -4.5 -0.38 1.51e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs926938 0.584 rs360607 chr1:115392401 C/A cg12756093 chr1:115239321 AMPD1 0.4 5.77 0.46 5.88e-8 Autism; TGCT cis rs2637266 1.000 rs6480827 chr10:78356333 T/G cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT trans rs4332037 0.539 rs4470910 chr7:2071723 C/T cg10840412 chr1:235813424 GNG4 0.96 6.97 0.53 1.66e-10 Bipolar disorder; TGCT cis rs8028182 0.636 rs11636031 chr15:75815758 T/C cg20655648 chr15:75932815 IMP3 0.59 4.62 0.38 9.55e-6 Sudden cardiac arrest; TGCT cis rs9640161 0.750 rs3735173 chr7:150020526 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.65 0.39 8.41e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs6582630 0.555 rs11503799 chr12:38294578 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7567389 0.740 rs4536600 chr2:128002572 A/G cg09760422 chr2:128146352 NA 0.35 4.82 0.4 4.09e-6 Self-rated health; TGCT cis rs11105298 0.891 rs11105319 chr12:89927177 G/A cg00757033 chr12:89920650 WDR51B 0.29 4.56 0.38 1.22e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6460942 0.915 rs1595800 chr7:12439816 G/A cg06484146 chr7:12443880 VWDE -0.57 -5.46 -0.44 2.47e-7 Coronary artery disease; TGCT cis rs9807989 0.839 rs6543123 chr2:102977196 C/T cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs7824557 0.767 rs2164272 chr8:11162496 A/C cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs10791323 0.581 rs2723608 chr11:133710149 A/G cg15485101 chr11:133734466 NA 0.39 5.03 0.41 1.71e-6 Childhood ear infection; TGCT trans rs6089829 0.925 rs11086152 chr20:61664656 T/C cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs17376456 0.877 rs10078194 chr5:93364310 A/C cg25358565 chr5:93447407 FAM172A 0.92 8.4 0.6 8.88e-14 Diabetic retinopathy; TGCT cis rs7044106 0.537 rs4434680 chr9:123489688 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 7.0 0.53 1.45e-10 Hip circumference adjusted for BMI; TGCT cis rs3812831 0.654 rs9314900 chr13:114937618 A/C cg08824895 chr13:115047677 UPF3A 0.47 4.88 0.4 3.18e-6 Schizophrenia; TGCT cis rs72781680 0.898 rs72786276 chr2:24062566 G/A cg08917208 chr2:24149416 ATAD2B 0.9 5.6 0.45 1.29e-7 Lymphocyte counts; TGCT cis rs7727544 0.735 rs2631370 chr5:131703776 T/C cg24060327 chr5:131705240 SLC22A5 0.59 6.61 0.51 1.01e-9 Blood metabolite levels; TGCT cis rs9303542 0.559 rs62066693 chr17:46617530 G/C cg25032089 chr17:46643351 HOXB3 0.56 5.33 0.43 4.44e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs1949733 1.000 rs3103072 chr4:8508431 C/T cg13073564 chr4:8508604 NA 0.47 4.94 0.41 2.49e-6 Response to antineoplastic agents; TGCT cis rs9911578 1.000 rs302854 chr17:56683612 G/A cg12560992 chr17:57184187 TRIM37 0.75 9.13 0.63 1.64e-15 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.571 rs2050032 chr22:42152429 C/T cg03806693 chr22:41940476 POLR3H 0.93 8.76 0.62 1.21e-14 Vitiligo; TGCT cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg00684032 chr4:1343700 KIAA1530 -0.22 -4.72 -0.39 6.18e-6 Obesity-related traits; TGCT cis rs1008375 0.966 rs11733730 chr4:17625209 G/C cg10189774 chr4:17578691 LAP3 0.66 5.74 0.46 6.81e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg03188948 chr7:1209495 NA 0.71 6.3 0.49 4.79e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs751984 0.852 rs10897164 chr11:61277775 A/G cg17652291 chr11:60500967 NA -0.41 -4.58 -0.38 1.1e-5 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs57994353 0.897 rs11999609 chr9:139363539 C/T cg13741927 chr9:139327495 INPP5E -0.26 -6.13 -0.48 1.06e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2836974 0.666 rs1888487 chr21:40683259 A/G cg06238570 chr21:40685208 BRWD1 -0.83 -9.11 -0.63 1.81e-15 Cognitive function; TGCT cis rs17253792 0.822 rs75115817 chr14:56069537 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7223966 1.000 rs8073373 chr17:61703320 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.17 0.42 9.12e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7698623 0.850 rs6813016 chr4:88768808 T/C cg27387453 chr4:88533842 DSPP -0.61 -4.64 -0.38 8.7e-6 Cardiovascular disease risk factors; TGCT cis rs4713118 0.516 rs4713142 chr6:28106347 T/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Parkinson's disease; TGCT cis rs5769765 0.862 rs9616380 chr22:50312225 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT trans rs3780486 1.000 rs10813951 chr9:33128021 C/T cg20290983 chr6:43655470 MRPS18A -1.1 -10.76 -0.69 1.75e-19 IgG glycosylation; TGCT cis rs72945132 0.882 rs12282678 chr11:70152457 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7089973 0.604 rs10885618 chr10:116617718 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.61 0.45 1.26e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9911578 1.000 rs9897326 chr17:56902297 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg09737314 chr17:6899359 ALOX12 0.51 5.31 0.43 4.82e-7 Tonsillectomy; TGCT cis rs7552404 1.000 rs12127402 chr1:76205643 C/A cg10523679 chr1:76189770 ACADM 0.9 9.71 0.66 6.5e-17 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs17471911 0.708 rs78287224 chr10:100778265 C/T cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs4819052 0.851 rs4819044 chr21:46660118 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.62 5.22 0.42 7.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.65 0.39 8.32e-6 Obesity-related traits; TGCT cis rs78456975 0.941 rs13412229 chr2:1520381 C/T cg01028140 chr2:1542097 TPO -0.35 -4.73 -0.39 6.04e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7267979 0.966 rs2261795 chr20:25263136 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4891159 0.730 rs11874719 chr18:74101053 A/G cg24786174 chr18:74118243 ZNF516 -0.58 -9.07 -0.63 2.19e-15 Longevity; TGCT trans rs3780486 0.629 rs10971439 chr9:33180813 C/T cg20290983 chr6:43655470 MRPS18A -0.99 -7.03 -0.53 1.24e-10 IgG glycosylation; TGCT cis rs34638657 0.673 rs11645286 chr16:82201898 C/A cg09439754 chr16:82129088 HSD17B2 -0.25 -4.66 -0.39 7.87e-6 Lung adenocarcinoma; TGCT cis rs1729951 0.546 rs12054218 chr3:136677496 C/G cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs7089973 0.604 rs7897937 chr10:116591318 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.75 0.46 6.46e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs597539 0.616 rs473997 chr11:68639481 C/T cg06028808 chr11:68637592 NA 0.52 6.73 0.52 5.58e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10992471 0.575 rs2147060 chr9:95160477 T/C cg13798575 chr9:95087839 CENPP;NOL8 0.52 4.79 0.39 4.74e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg03806693 chr22:41940476 POLR3H -1.14 -13.03 -0.76 5.42e-25 Vitiligo; TGCT cis rs9443645 0.869 rs7756858 chr6:79619968 A/G cg09184832 chr6:79620586 NA -0.5 -5.43 -0.44 2.87e-7 Intelligence (multi-trait analysis); TGCT cis rs1348850 0.567 rs3821006 chr2:178537694 G/A cg22681709 chr2:178499509 PDE11A -0.49 -6.15 -0.48 9.86e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2276314 0.857 rs16967327 chr18:33587036 C/T cg19628046 chr18:33552617 C18orf21 0.51 4.46 0.37 1.79e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs453301 0.522 rs2929455 chr8:9083433 A/T cg15556689 chr8:8085844 FLJ10661 -0.59 -5.36 -0.43 3.91e-7 Joint mobility (Beighton score); TGCT cis rs11679640 0.836 rs17682575 chr2:43152304 C/T cg17485141 chr2:42566556 NA -0.27 -4.49 -0.37 1.58e-5 White matter hyperintensity burden; TGCT cis rs2307449 0.729 rs1006659 chr15:89883672 T/G cg01877814 chr15:89879097 POLG 0.29 4.53 0.38 1.36e-5 Menopause (age at onset); TGCT cis rs10089 1.000 rs4836361 chr5:127459991 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs763121 0.752 rs5757222 chr22:39060473 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.9e-12 Menopause (age at onset); TGCT cis rs9611519 0.780 rs1535048 chr22:41684093 C/T cg13695892 chr22:41940480 POLR3H -0.66 -6.02 -0.48 1.82e-8 Neuroticism; TGCT cis rs3812831 0.695 rs7983872 chr13:114944781 T/G cg08824895 chr13:115047677 UPF3A 0.51 5.02 0.41 1.76e-6 Schizophrenia; TGCT cis rs11969893 0.737 rs4098482 chr6:101377808 C/T cg12253828 chr6:101329408 ASCC3 1.21 6.03 0.48 1.74e-8 Economic and political preferences (immigration/crime); TGCT cis rs61867294 0.553 rs6584645 chr10:106703759 C/T cg08000847 chr10:105880925 C10orf78 0.48 4.44 0.37 2e-5 Schizophrenia; TGCT cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg20849893 chr7:64541193 NA -0.51 -5.26 -0.43 6.15e-7 Calcium levels; TGCT cis rs422249 0.512 rs174562 chr11:61585144 A/G cg19610905 chr11:61596333 FADS2 -1.07 -12.03 -0.73 1.43e-22 Trans fatty acid levels; TGCT cis rs6681544 0.544 rs3790909 chr1:82379971 T/A cg04226724 chr1:82268649 LPHN2 0.47 4.95 0.41 2.33e-6 Metabolite levels (X-11787); TGCT cis rs6840360 1.000 rs4696285 chr4:152605449 A/G cg17479576 chr4:152424074 FAM160A1 -0.45 -4.69 -0.39 7e-6 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.558 rs1796382 chr12:42840955 C/G cg19980929 chr12:42632907 YAF2 -0.41 -5.8 -0.46 5.14e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs11098499 0.863 rs1480940 chr4:120457682 T/C cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs13191362 1.000 rs34138336 chr6:163144929 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.35 0.64 4.74e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs8062405 0.964 rs11864107 chr16:28885931 T/C cg09754948 chr16:28834200 ATXN2L 0.6 4.46 0.37 1.79e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9517320 0.534 rs4772090 chr13:99150674 T/C cg07423050 chr13:99094983 FARP1 -0.29 -5.88 -0.47 3.58e-8 Longevity; TGCT cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs2013441 1.000 rs972966 chr17:20030992 G/C cg23224458 chr17:20280056 CCDC144C 0.39 4.73 0.39 5.88e-6 Obesity-related traits; TGCT cis rs6598955 0.671 rs7544 chr1:26607726 T/G cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs6750047 0.516 rs458704 chr2:38318134 G/A cg07380506 chr2:38303506 CYP1B1 0.57 5.33 0.43 4.47e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg22963979 chr7:1858916 MAD1L1 -0.37 -5.8 -0.46 5.08e-8 Bipolar disorder and schizophrenia; TGCT cis rs2836974 0.897 rs2836923 chr21:40524236 T/C cg11890956 chr21:40555474 PSMG1 1.13 12.02 0.73 1.54e-22 Cognitive function; TGCT cis rs28595532 0.920 rs56291421 chr4:119732294 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7089973 0.668 rs10885622 chr10:116643844 C/T cg03647239 chr10:116582469 FAM160B1 0.55 5.19 0.42 8.49e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs4654899 0.932 rs10916943 chr1:21472429 T/C cg01072550 chr1:21505969 NA 0.51 8.3 0.6 1.5e-13 Superior frontal gyrus grey matter volume; TGCT cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg03396347 chr1:1875803 NA -0.37 -6.7 -0.52 6.64e-10 Body mass index; TGCT cis rs9914544 0.545 rs2386403 chr17:18769600 A/G cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs12893668 0.572 rs11846404 chr14:104156108 C/G cg26031613 chr14:104095156 KLC1 -0.59 -5.05 -0.41 1.53e-6 Reticulocyte count; TGCT cis rs12210905 1.000 rs72843608 chr6:27122750 G/A cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs12971120 0.891 rs12608037 chr18:72169395 A/G cg26446133 chr18:72167187 CNDP2 -0.37 -6.33 -0.49 4.13e-9 Refractive error; TGCT cis rs7605378 1.000 rs769954 chr2:200692159 C/G cg17644776 chr2:200775616 C2orf69 -0.28 -5.33 -0.43 4.51e-7 Osteoporosis; TGCT cis rs4253772 0.591 rs11703245 chr22:46684890 A/G cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs74417235 0.684 rs13179358 chr5:154059746 C/A cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs9916302 0.752 rs12150047 chr17:37601755 A/G cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs3020736 0.500 rs4147638 chr22:42487900 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT trans rs2469997 0.925 rs2447173 chr8:120359513 C/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs4862307 0.808 rs7666346 chr4:185000657 G/A cg06737308 chr4:185021514 ENPP6 -0.35 -5.13 -0.42 1.08e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs875971 1.000 rs7781698 chr7:65896312 A/T cg18876405 chr7:65276391 NA 0.32 4.83 0.4 3.98e-6 Aortic root size; TGCT cis rs6032067 0.673 rs6017532 chr20:43904095 C/T cg16667508 chr20:43936853 MATN4;RBPJL -0.46 -6.61 -0.51 1.03e-9 Blood protein levels; TGCT cis rs6540559 0.673 rs17015183 chr1:209948711 A/C cg04352962 chr1:209979756 IRF6 0.65 4.54 0.38 1.33e-5 Cleft lip with or without cleft palate; TGCT cis rs854765 0.583 rs8070722 chr17:17813562 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.7 0.57 3.68e-12 Total body bone mineral density; TGCT cis rs2811893 1.000 rs232851 chr1:59122871 A/G cg26196860 chr1:59745563 NA -0.24 -4.65 -0.39 8.26e-6 Diabetic retinopathy; TGCT trans rs208520 0.690 rs851467 chr6:66802721 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.83 -0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs6545883 0.965 rs12713439 chr2:61752154 G/A cg15711740 chr2:61764176 XPO1 -0.57 -5.25 -0.43 6.39e-7 Tuberculosis; TGCT cis rs11098499 0.866 rs6847778 chr4:120293582 A/G cg09307838 chr4:120376055 NA 0.57 5.56 0.45 1.6e-7 Corneal astigmatism; TGCT cis rs7726839 0.540 rs55929359 chr5:595956 C/G cg09021430 chr5:549028 NA -0.43 -5.59 -0.45 1.34e-7 Obesity-related traits; TGCT cis rs9926296 0.712 rs258330 chr16:89729574 T/G cg03388025 chr16:89894329 SPIRE2 -0.36 -5.33 -0.43 4.49e-7 Vitiligo; TGCT cis rs7772486 0.875 rs6934467 chr6:146410529 G/T cg23711669 chr6:146136114 FBXO30 0.89 9.8 0.66 3.86e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1546060 0.668 rs9876122 chr3:56465762 A/G cg24436196 chr3:56448270 ERC2 0.18 4.48 0.37 1.67e-5 Night sleep phenotypes; TGCT cis rs11031096 0.678 rs12223062 chr11:4180178 G/T cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1048238 0.506 rs56352596 chr1:16297592 G/A cg21385522 chr1:16154831 NA 0.61 6.94 0.53 1.95e-10 Systolic blood pressure; TGCT cis rs56873913 0.904 rs7251295 chr19:50096859 G/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.62 0.45 1.19e-7 Schizophrenia; TGCT cis rs9733 0.566 rs72702554 chr1:150678234 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.81 0.4 4.38e-6 Tonsillectomy; TGCT cis rs548181 0.604 rs11608103 chr11:125627917 G/A cg03464685 chr11:125439445 EI24 -0.84 -5.52 -0.44 1.93e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs743757 1.000 rs734767 chr3:50431410 C/G cg16953475 chr3:49711973 APEH 0.73 4.81 0.4 4.22e-6 Diastolic blood pressure; TGCT cis rs72627509 0.904 rs12645070 chr4:57770106 G/A cg26694713 chr4:57773883 REST 0.74 6.67 0.51 7.45e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9911578 1.000 rs9807057 chr17:56889952 A/C cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs3892630 0.824 rs12976069 chr19:33280084 G/A cg22980127 chr19:33182716 NUDT19 0.7 5.07 0.41 1.44e-6 Red blood cell traits; TGCT cis rs887829 0.569 rs3806597 chr2:234637569 C/T cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 0.26 4.46 0.37 1.84e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs9467711 1.000 rs9467713 chr6:26338128 T/C cg02458000 chr6:26745757 NA -1.07 -6.66 -0.51 7.97e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs8077889 0.871 rs72836549 chr17:41904360 G/T cg26893861 chr17:41843967 DUSP3 1.08 12.97 0.76 7.86e-25 Triglycerides; TGCT cis rs939574 1.000 rs939574 chr2:220118531 G/C cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.05 -6.46 -0.5 2.12e-9 Platelet distribution width; TGCT cis rs12477438 1.000 rs6542873 chr2:99824965 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.85 -8.3 -0.6 1.52e-13 Chronic sinus infection; TGCT cis rs79349575 0.783 rs62075820 chr17:46983171 G/C cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT cis rs16867321 0.901 rs768116 chr2:181511012 A/G cg23363182 chr2:181467187 NA -0.41 -5.54 -0.45 1.73e-7 Obesity; TGCT cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg03264133 chr6:25882463 NA 0.5 5.29 0.43 5.3e-7 Blood metabolite levels; TGCT cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg03060546 chr3:49711283 APEH -0.51 -4.91 -0.4 2.84e-6 Menarche (age at onset); TGCT cis rs7843479 0.965 rs11784535 chr8:21857787 G/A cg17168535 chr8:21777572 XPO7 0.64 5.82 0.46 4.81e-8 Mean corpuscular volume; TGCT cis rs236907 0.812 rs2232807 chr1:171750095 T/C cg20598894 chr1:171756153 METTL13 -0.19 -4.47 -0.37 1.72e-5 Mean platelet volume; TGCT trans rs561341 0.882 rs504887 chr17:30322881 T/A cg20587970 chr11:113659929 NA -1.02 -12.58 -0.75 6.75e-24 Hip circumference adjusted for BMI; TGCT cis rs6089584 1.000 rs6142910 chr20:60562181 C/A cg16423285 chr20:60520624 NA -0.52 -5.45 -0.44 2.6e-7 Body mass index; TGCT cis rs2228479 0.681 rs11641790 chr16:89961957 A/G cg06558623 chr16:89946397 TCF25 -0.43 -4.99 -0.41 1.96e-6 Skin colour saturation; TGCT cis rs17102423 0.755 rs884683 chr14:65574482 C/T cg11161011 chr14:65562177 MAX -0.54 -7.49 -0.56 1.15e-11 Obesity-related traits; TGCT cis rs1075232 0.510 rs78884938 chr15:31510885 C/T cg01030201 chr15:31746330 NA -0.87 -4.47 -0.37 1.76e-5 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs1153858 1.000 rs10519021 chr15:45631795 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs7980687 0.638 rs7299943 chr12:123593485 A/T cg00376283 chr12:123451042 ABCB9 0.67 4.81 0.4 4.34e-6 Height;Educational attainment;Head circumference (infant); TGCT cis rs28595532 0.920 rs115259971 chr4:119762654 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs13256369 0.802 rs11249883 chr8:8561537 G/A cg18904891 chr8:8559673 CLDN23 0.57 5.27 0.43 5.87e-7 Obesity-related traits; TGCT cis rs7552404 1.000 rs7534754 chr1:76185308 G/A cg10523679 chr1:76189770 ACADM 0.91 9.87 0.66 2.66e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11718455 0.921 rs35872933 chr3:44028515 T/G cg08738300 chr3:44038990 NA 0.85 6.31 0.49 4.55e-9 Coronary artery disease; TGCT cis rs12887734 0.546 rs4900597 chr14:104266664 A/G cg26031613 chr14:104095156 KLC1 0.76 6.81 0.52 3.71e-10 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7614311 0.731 rs73130544 chr3:63868596 G/A cg22134162 chr3:63841271 THOC7 -0.4 -5.27 -0.43 5.98e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs3806843 0.900 rs116210441 chr5:140128649 T/A cg19875535 chr5:140030758 IK -0.35 -5.75 -0.46 6.59e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9467711 0.651 rs13198474 chr6:25874423 G/A cg16898833 chr6:26189333 HIST1H4D 1.36 6.0 0.47 2.05e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.512 rs5758465 chr22:42175314 T/C cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg07061783 chr6:25882402 NA 0.64 6.7 0.52 6.57e-10 Blood metabolite levels; TGCT cis rs12360000 0.770 rs12251959 chr10:1902277 C/T cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs12477438 0.765 rs6740054 chr2:99576631 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.79 -7.82 -0.57 1.99e-12 Chronic sinus infection; TGCT trans rs12599106 0.679 rs34584967 chr16:34475725 T/G cg03395511 chr6:291903 DUSP22 -0.64 -6.8 -0.52 3.97e-10 Menopause (age at onset); TGCT cis rs713587 0.563 rs7605335 chr2:25109317 G/A cg01884057 chr2:25150051 NA 0.31 5.82 0.46 4.71e-8 Body mass index in non-asthmatics; TGCT cis rs4803468 1.000 rs2241709 chr19:41912250 C/T cg09537434 chr19:41945824 ATP5SL -0.93 -11.06 -0.7 3.31e-20 Height; TGCT cis rs6460942 0.915 rs62448600 chr7:12454944 T/G cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs2295359 0.724 rs10489630 chr1:67662622 G/T cg12940439 chr1:67600707 NA -0.44 -4.9 -0.4 2.89e-6 Psoriasis; TGCT cis rs7017914 0.905 rs3110243 chr8:71933069 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs7582180 0.652 rs4851311 chr2:100980398 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.86 -0.4 3.45e-6 Intelligence (multi-trait analysis); TGCT cis rs634534 0.562 rs1151505 chr11:65734539 C/T cg04055107 chr11:65626734 MUS81;CFL1 0.46 4.48 0.37 1.65e-5 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs17401966 0.597 rs11121555 chr1:10442856 C/T cg19773385 chr1:10388646 KIF1B -0.22 -5.1 -0.42 1.23e-6 Hepatocellular carcinoma; TGCT cis rs6964587 1.000 rs10235941 chr7:91587050 T/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs801193 0.660 rs2659897 chr7:66187715 A/G cg11764359 chr7:65958608 NA -0.59 -5.17 -0.42 9.13e-7 Aortic root size; TGCT cis rs17102884 0.506 rs4899540 chr14:75403408 G/A cg08847533 chr14:75593920 NEK9 -0.62 -5.5 -0.44 2.09e-7 Neuroticism; TGCT cis rs7552404 1.000 rs7516226 chr1:76234257 G/A cg22875332 chr1:76189707 ACADM 0.77 8.99 0.63 3.37e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs250677 0.687 rs36043 chr5:148440983 G/A cg23229984 chr5:148520753 ABLIM3 0.21 4.99 0.41 1.98e-6 Breast cancer; TGCT cis rs11252926 0.574 rs4881254 chr10:453567 C/T cg13477178 chr10:375248 DIP2C -0.25 -4.72 -0.39 6.33e-6 Psychosis in Alzheimer's disease; TGCT cis rs7772486 0.754 rs9386133 chr6:146141213 A/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.66 -0.39 8.04e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs16921807 chr8:58105967 C/T cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs3784262 0.904 rs17820823 chr15:58239358 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.29 -0.55 3.16e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4780401 0.609 rs9923954 chr16:11816855 G/T cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs1878931 0.624 rs37810 chr16:3451881 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.26 -0.49 5.69e-9 Body mass index (adult); TGCT cis rs116095464 0.558 rs10462754 chr5:246669 T/C cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs1008375 1.000 rs10805358 chr4:17652450 A/C cg16339924 chr4:17578868 LAP3 0.6 5.08 0.42 1.34e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9926296 1.000 rs9926296 chr16:89818089 A/G cg21285383 chr16:89894308 SPIRE2 0.38 5.73 0.46 7.35e-8 Vitiligo; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT trans rs208515 0.525 rs4145045 chr6:66678949 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.92 10.09 0.67 7.45e-18 Exhaled nitric oxide levels; TGCT cis rs1577917 0.837 rs10944157 chr6:86577199 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.04 -0.41 1.64e-6 Response to antipsychotic treatment; TGCT trans rs6089829 0.962 rs11086151 chr20:61664644 C/T cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs587847 0.737 rs8040571 chr15:37626493 C/A cg00216138 chr15:37171175 LOC145845 0.3 4.52 0.38 1.43e-5 Intraocular pressure; TGCT cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs10507380 0.824 rs76246060 chr13:27909484 G/A cg25543773 chr13:27185723 WASF3 0.32 4.58 0.38 1.09e-5 Electrocardiographic traits; TGCT cis rs7647973 1.000 rs3866330 chr3:49582994 T/C cg05785598 chr3:49045655 WDR6 0.37 4.59 0.38 1.05e-5 Menarche (age at onset); TGCT cis rs7000551 0.556 rs6998780 chr8:22254639 C/T cg12081754 chr8:22256438 SLC39A14 0.33 4.82 0.4 4.13e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs79349575 0.783 rs4793991 chr17:47001801 A/G cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs7666738 0.830 rs13111977 chr4:98953813 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs713587 0.571 rs2438679 chr2:25317653 C/T cg01884057 chr2:25150051 NA -0.26 -4.88 -0.4 3.16e-6 Body mass index in non-asthmatics; TGCT cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg23758822 chr17:41437982 NA 0.69 6.94 0.53 1.94e-10 Menopause (age at onset); TGCT cis rs7523273 0.564 rs1977268 chr1:207881036 A/C cg22525895 chr1:207977042 MIR29B2 0.29 4.6 0.38 1.02e-5 Schizophrenia; TGCT cis rs6912958 0.500 rs4707352 chr6:87929705 G/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.44 -5.82 -0.46 4.71e-8 Monocyte percentage of white cells; TGCT cis rs6951245 0.554 rs79367977 chr7:1152657 G/A cg23708337 chr7:1209742 NA 0.44 4.99 0.41 2e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9357506 1.000 rs9367243 chr6:46316112 A/C cg21115430 chr6:46460003 NA 0.24 4.95 0.41 2.36e-6 Body mass index; TGCT cis rs7819412 0.765 rs7000132 chr8:11030935 T/C cg21775007 chr8:11205619 TDH -0.56 -5.12 -0.42 1.11e-6 Triglycerides; TGCT cis rs9858542 0.953 rs9824092 chr3:49674147 C/G cg03060546 chr3:49711283 APEH -0.64 -5.7 -0.46 8.18e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs514406 0.560 rs1889033 chr1:53211887 A/G cg01802117 chr1:53393560 SCP2 0.44 5.14 0.42 1.05e-6 Monocyte count; TGCT cis rs7178572 0.568 rs11636554 chr15:77608747 C/T cg15453836 chr15:77711506 NA -0.43 -4.87 -0.4 3.4e-6 Type 2 diabetes; TGCT cis rs10256972 0.758 rs2280724 chr7:1064720 A/G cg03188948 chr7:1209495 NA 0.42 5.61 0.45 1.24e-7 Longevity;Endometriosis; TGCT cis rs7954584 0.567 rs1720033 chr12:122384344 C/T cg21171335 chr12:122356390 WDR66 -0.71 -7.5 -0.56 1.06e-11 Mean corpuscular volume; TGCT cis rs3008870 0.958 rs12131222 chr1:67438535 A/T cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs3784262 0.565 rs2642630 chr15:58316960 C/G cg12031962 chr15:58353849 ALDH1A2 -0.39 -5.54 -0.45 1.72e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs3812049 1.000 rs3812049 chr5:127418850 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.65 5.96 0.47 2.46e-8 Lymphocyte counts;Red cell distribution width; TGCT cis rs476633 0.691 rs6492997 chr15:41541171 G/A cg18705301 chr15:41695430 NDUFAF1 -0.57 -7.44 -0.56 1.44e-11 Glomerular filtration rate (creatinine); TGCT cis rs7953249 0.791 rs1920792 chr12:121404584 T/C cg00044289 chr12:121019603 POP5 -0.41 -4.57 -0.38 1.14e-5 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs478304 0.934 rs537786 chr11:65494987 C/T cg27068330 chr11:65405492 SIPA1 0.76 7.47 0.56 1.25e-11 Acne (severe); TGCT cis rs644799 0.930 rs3802764 chr11:95514599 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 11.08 0.71 2.9e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9394841 0.692 rs9349202 chr6:41805581 A/C cg08135965 chr6:41755394 TOMM6 0.54 4.94 0.41 2.46e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs936229 0.813 rs7085 chr15:75095483 T/C cg10253484 chr15:75165896 SCAMP2 -0.65 -5.19 -0.42 8.24e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs12579753 0.917 rs7132465 chr12:82205840 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs2688608 0.592 rs7080579 chr10:75504029 T/A cg19442545 chr10:75533431 FUT11 -0.36 -5.66 -0.45 9.76e-8 Inflammatory bowel disease; TGCT cis rs76878669 0.561 rs2236679 chr11:66108894 G/C cg18002602 chr11:66138449 SLC29A2 -0.53 -6.44 -0.5 2.32e-9 Educational attainment (years of education); TGCT cis rs10875746 0.859 rs11558768 chr12:48577789 C/T cg20731937 chr12:48336164 NA 0.61 4.88 0.4 3.17e-6 Longevity (90 years and older); TGCT cis rs853679 0.517 rs1904841 chr6:28108085 C/T cg12963246 chr6:28129442 ZNF389 0.53 5.09 0.42 1.27e-6 Depression; TGCT trans rs1496653 0.602 rs35028631 chr3:23443819 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs12612619 0.627 rs13391244 chr2:27287609 T/C cg03606774 chr2:27432830 SLC5A6 -0.28 -4.63 -0.38 8.97e-6 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs7267979 1.000 rs11087520 chr20:25436827 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2730260 0.578 rs56375711 chr7:158854935 G/A cg09066883 chr7:157932951 PTPRN2 0.43 4.65 0.39 8.22e-6 Myopia (pathological); TGCT cis rs12477438 0.520 rs6712704 chr2:99719687 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs9926296 0.585 rs6500441 chr16:89828669 C/G cg21285383 chr16:89894308 SPIRE2 0.43 6.47 0.5 2.03e-9 Vitiligo; TGCT cis rs4891159 0.790 rs8085133 chr18:74144083 A/C cg24786174 chr18:74118243 ZNF516 -0.55 -7.86 -0.58 1.61e-12 Longevity; TGCT cis rs60843830 1.000 rs62114497 chr2:214837 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.7 6.44 0.5 2.37e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs6088590 0.582 rs6059909 chr20:33139691 C/A cg06115741 chr20:33292138 TP53INP2 0.54 4.72 0.39 6.29e-6 Coronary artery disease; TGCT cis rs270601 0.710 rs4705852 chr5:131602807 A/G cg12564285 chr5:131593104 PDLIM4 0.4 4.78 0.39 4.79e-6 Acylcarnitine levels; TGCT cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg08296037 chr16:1584118 IFT140;TMEM204 -0.3 -5.3 -0.43 5.02e-7 Coronary artery disease; TGCT cis rs4790312 0.513 rs12939002 chr17:1965096 C/T cg24156229 chr17:1948635 NA -0.37 -5.95 -0.47 2.51e-8 Left atrial antero-posterior diameter; TGCT cis rs9814567 0.727 rs4245908 chr3:134349205 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.27 -0.49 5.37e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9611565 0.592 rs1811113 chr22:42073134 C/T cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Vitiligo; TGCT cis rs9910055 0.821 rs4473241 chr17:42281282 G/T cg13607699 chr17:42295918 UBTF 0.67 6.26 0.49 5.86e-9 Total body bone mineral density; TGCT cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6460942 0.555 rs7803268 chr7:12306793 G/A cg06484146 chr7:12443880 VWDE -0.54 -4.77 -0.39 5.06e-6 Coronary artery disease; TGCT cis rs10936602 0.527 rs9838444 chr3:169547573 A/G cg08193579 chr3:169529701 LRRC34 0.28 5.16 0.42 9.66e-7 Renal cell carcinoma; TGCT cis rs3782455 1.000 rs78363483 chr12:114401643 T/C cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10465746 0.846 rs12146038 chr1:84405065 A/T cg10977910 chr1:84465055 TTLL7 0.65 6.56 0.51 1.31e-9 Obesity-related traits; TGCT cis rs2180341 1.000 rs2180341 chr6:127600630 C/T cg24812749 chr6:127587940 RNF146 0.99 7.73 0.57 3.25e-12 Breast cancer; TGCT cis rs42648 1.000 rs42658 chr7:89981915 T/A cg25739043 chr7:89950458 NA -0.57 -5.49 -0.44 2.13e-7 Homocysteine levels; TGCT cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg08280861 chr8:58055591 NA 0.49 5.51 0.44 1.98e-7 Developmental language disorder (linguistic errors); TGCT cis rs7727544 0.716 rs4705926 chr5:131561758 C/T cg24060327 chr5:131705240 SLC22A5 -0.54 -5.1 -0.42 1.22e-6 Blood metabolite levels; TGCT cis rs73198271 1.000 rs11775476 chr8:8607869 T/C ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs259282 0.628 rs2287669 chr19:33110204 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.54 4.91 0.4 2.76e-6 Schizophrenia; TGCT cis rs7267979 1.000 rs12428 chr20:25433821 G/T cg14121845 chr20:25566513 NINL -0.44 -4.8 -0.4 4.48e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6450176 0.909 rs1541681 chr5:53304620 G/T ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs9883204 0.807 rs11708067 chr3:123065778 A/G cg04890266 chr3:123102914 ADCY5 0.35 4.85 0.4 3.59e-6 Birth weight; TGCT cis rs9291683 0.517 rs11736479 chr4:10017387 G/C cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Bone mineral density; TGCT cis rs3733585 0.673 rs4235348 chr4:9951968 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.65 -0.57 4.78e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2303745 0.841 rs10409801 chr19:17407415 A/G cg02221750 chr19:17393354 ANKLE1 -0.44 -4.67 -0.39 7.63e-6 Systemic lupus erythematosus; TGCT cis rs7829975 0.626 rs907183 chr8:8729761 C/G cg15556689 chr8:8085844 FLJ10661 -0.67 -6.34 -0.49 3.84e-9 Mood instability; TGCT cis rs67311347 0.911 rs6773917 chr3:40469254 G/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs79349575 0.756 rs937301 chr17:47046276 A/G cg07967210 chr17:47022446 SNF8 -0.44 -5.94 -0.47 2.68e-8 Type 2 diabetes; TGCT cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg12311346 chr5:56204834 C5orf35 -0.63 -6.36 -0.5 3.5e-9 Initial pursuit acceleration; TGCT cis rs2120019 0.938 rs1867150 chr15:75321139 T/C cg09165964 chr15:75287851 SCAMP5 -1.14 -10.33 -0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg07167872 chr1:205819463 PM20D1 0.59 7.68 0.57 4.23e-12 Menarche (age at onset); TGCT trans rs2675662 0.525 rs12264025 chr10:75494450 A/G cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Psoriasis vulgaris;Psoriasis; TGCT cis rs2204008 0.683 rs12370288 chr12:38127740 G/A cg26384229 chr12:38710491 ALG10B 0.89 7.92 0.58 1.14e-12 Bladder cancer; TGCT cis rs9916302 0.851 rs11868029 chr17:37650304 A/G cg07936489 chr17:37558343 FBXL20 -0.6 -4.75 -0.39 5.45e-6 Glomerular filtration rate (creatinine); TGCT cis rs317689 0.513 rs317659 chr12:69686132 T/A cg20891283 chr12:69753455 YEATS4 0.56 5.13 0.42 1.1e-6 Response to diuretic therapy; TGCT cis rs7264396 0.635 rs6060685 chr20:34512023 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs2932538 0.744 rs6537742 chr1:113085197 G/T cg22162597 chr1:113214053 CAPZA1 0.29 5.4 0.44 3.19e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1568889 1.000 rs6484346 chr11:28040767 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.86 8.94 0.63 4.66e-15 Bipolar disorder; TGCT cis rs13191362 1.000 rs13215491 chr6:163010325 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2996428 0.667 rs61768933 chr1:3766587 G/A cg13057898 chr1:3703894 LRRC47 0.21 4.64 0.38 8.81e-6 Red cell distribution width; TGCT cis rs28595532 0.800 rs114321375 chr4:119341663 G/A cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs868036 0.645 rs28539889 chr15:68121428 T/A cg05925327 chr15:68127851 NA -0.48 -4.6 -0.38 1.05e-5 Restless legs syndrome; TGCT cis rs9467773 1.000 rs9467791 chr6:26562486 A/G cg09904177 chr6:26538194 HMGN4 -0.67 -6.77 -0.52 4.63e-10 Intelligence (multi-trait analysis); TGCT cis rs4919694 1.000 rs77318450 chr10:104733098 A/G cg04362960 chr10:104952993 NT5C2 1.07 7.15 0.54 6.49e-11 Arsenic metabolism; TGCT cis rs3741404 0.609 rs666497 chr11:63869821 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.72 7.32 0.55 2.78e-11 Platelet count; TGCT cis rs12200560 0.505 rs211171 chr6:97070579 T/G cg06623918 chr6:96969491 KIAA0776 0.59 5.02 0.41 1.76e-6 Coronary heart disease; TGCT cis rs7659604 0.539 rs2221628 chr4:122795361 G/A cg06713675 chr4:122721982 EXOSC9 -0.67 -8.73 -0.62 1.41e-14 Type 2 diabetes; TGCT cis rs2847281 0.561 rs888271 chr18:12774981 A/G cg23598886 chr18:12777645 NA 0.37 4.69 0.39 7.07e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs6754311 0.689 rs192822 chr2:136682274 A/T cg07169764 chr2:136633963 MCM6 0.63 5.87 0.47 3.81e-8 Mosquito bite size; TGCT cis rs8002180 0.959 rs7996898 chr13:95922453 A/G cg24476569 chr13:95954382 ABCC4 0.41 5.07 0.41 1.42e-6 Blood metabolite levels; TGCT cis rs7830933 0.911 rs13251678 chr8:23594229 C/T cg04349084 chr8:23602677 NA 0.23 4.59 0.38 1.08e-5 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs8051431 0.876 rs8061657 chr16:72016695 A/G cg06353428 chr16:71660113 MARVELD3 0.57 4.61 0.38 9.79e-6 LDL cholesterol levels; TGCT cis rs9948 0.786 rs111237064 chr2:97456578 T/C cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs35306767 0.807 rs11253513 chr10:968450 C/T cg26597838 chr10:835615 NA 0.63 9.0 0.63 3.31e-15 Eosinophil percentage of granulocytes; TGCT cis rs13242816 1.000 rs34082946 chr7:116154313 G/A cg16553024 chr7:116138462 CAV2 -0.45 -5.27 -0.43 5.81e-7 P wave duration; TGCT cis rs2637266 1.000 rs7101318 chr10:78379780 T/C cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs3770081 1.000 rs111295372 chr2:86283357 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs1153858 1.000 rs66714503 chr15:45648038 G/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs12497850 0.931 rs11924597 chr3:48937790 T/C cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT trans rs17685 0.784 rs1613890 chr7:75735037 T/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.3 0.6 1.51e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs9790314 0.586 rs35713426 chr3:161131271 A/G cg03342759 chr3:160939853 NMD3 -0.5 -5.1 -0.42 1.25e-6 Morning vs. evening chronotype; TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs951366 0.903 rs823116 chr1:205720483 G/A cg07157834 chr1:205819609 PM20D1 0.34 5.01 0.41 1.81e-6 Menarche (age at onset); TGCT cis rs7772486 0.686 rs2179323 chr6:145982786 T/G cg23711669 chr6:146136114 FBXO30 -0.84 -9.16 -0.64 1.35e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs3820068 0.608 rs12091644 chr1:16044945 G/A cg17385448 chr1:15911702 AGMAT 0.35 4.65 0.39 8.37e-6 Systolic blood pressure; TGCT cis rs2836974 1.000 rs2836974 chr21:40663181 A/G cg11644478 chr21:40555479 PSMG1 -1.01 -10.78 -0.7 1.56e-19 Cognitive function; TGCT cis rs4799461 0.778 rs62081464 chr18:35142133 C/T cg27332583 chr18:35150602 NA 0.3 4.61 0.38 9.9e-6 Neuroticism; TGCT cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg18305652 chr10:134549665 INPP5A 0.35 5.94 0.47 2.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4654899 0.643 rs651538 chr1:21097866 A/G cg01072550 chr1:21505969 NA -0.54 -8.85 -0.62 7.62e-15 Superior frontal gyrus grey matter volume; TGCT cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.17 -0.42 9.08e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs910316 1.000 rs12589876 chr14:75544189 G/A cg08847533 chr14:75593920 NEK9 0.96 10.53 0.69 6.43e-19 Height; TGCT cis rs763121 0.853 rs8138996 chr22:39047435 G/T cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs12477438 0.520 rs6743355 chr2:99732360 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg06634786 chr22:41940651 POLR3H 0.73 6.81 0.52 3.75e-10 Vitiligo; TGCT cis rs6089829 0.889 rs6122348 chr20:61663921 C/T cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7172809 0.897 rs1317320 chr15:77830090 G/A cg22256960 chr15:77711686 NA -0.44 -4.47 -0.37 1.76e-5 Glucose homeostasis traits; TGCT cis rs477895 0.713 rs35095324 chr11:63948412 G/A cg23719950 chr11:63933701 MACROD1 -0.71 -5.87 -0.47 3.72e-8 Mean platelet volume; TGCT cis rs6815814 0.731 rs4513579 chr4:38773816 T/C cg02016764 chr4:38805732 TLR1 -0.28 -4.79 -0.4 4.63e-6 Breast cancer; TGCT cis rs28595532 0.920 rs115334469 chr4:119596194 G/C cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.12e-11 Cannabis dependence symptom count; TGCT cis rs11230394 0.916 rs17627710 chr11:60379083 G/A cg24026212 chr11:59952134 MS4A6A 0.32 5.05 0.41 1.57e-6 Gestational age at birth in premature rupture of membrane-initiated deliveries (child effect); TGCT cis rs7267979 0.657 rs6107073 chr20:25716363 T/C cg03522245 chr20:25566470 NINL 0.51 5.28 0.43 5.62e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6089829 0.962 rs6122347 chr20:61661866 C/T cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1552244 0.572 rs17032440 chr3:10169819 A/C cg00149659 chr3:10157352 C3orf10 -1.16 -7.48 -0.56 1.21e-11 Alzheimer's disease; TGCT cis rs172166 0.516 rs2021826 chr6:28132756 G/A cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.71 -0.39 6.43e-6 Cardiac Troponin-T levels; TGCT cis rs9372498 0.536 rs62424175 chr6:118797381 T/A cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.36e-7 Diastolic blood pressure; TGCT cis rs9291683 0.517 rs11736479 chr4:10017387 G/C cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Bone mineral density; TGCT cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg11941060 chr3:133502564 NA -0.32 -6.61 -0.51 1.01e-9 Iron status biomarkers; TGCT cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg17971929 chr21:40555470 PSMG1 0.96 8.86 0.62 6.96e-15 Cognitive function; TGCT cis rs4845570 1.000 rs17568246 chr1:151736456 A/G cg07092448 chr1:151763213 TDRKH -1.05 -7.56 -0.56 7.85e-12 Coronary artery disease; TGCT cis rs7107174 1.000 rs4944198 chr11:78032605 T/A cg12700464 chr11:78128424 GAB2 -0.67 -4.78 -0.39 4.82e-6 Testicular germ cell tumor; TGCT cis rs9527 0.615 rs7089065 chr10:104723022 C/T cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs13191362 1.000 rs13215491 chr6:163010325 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9443645 0.901 rs2174739 chr6:79659170 C/T cg05283184 chr6:79620031 NA 0.22 4.99 0.41 2.01e-6 Intelligence (multi-trait analysis); TGCT cis rs17030434 0.784 rs11099900 chr4:154669471 C/T cg14289246 chr4:154710475 SFRP2 -0.86 -7.36 -0.55 2.24e-11 Electrocardiographic conduction measures; TGCT cis rs7666738 0.830 rs1967980 chr4:98966426 C/G cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10949834 0.652 rs2269082 chr7:73519875 A/G cg07137043 chr7:73588983 EIF4H -0.67 -5.12 -0.42 1.14e-6 Verbal memory performance (residualized delayed recall change); TGCT cis rs61774743 0.557 rs4359027 chr1:41848296 G/A cg01193554 chr1:41846683 NA -0.41 -5.01 -0.41 1.86e-6 Intelligence (multi-trait analysis); TGCT cis rs6750047 0.638 rs336031 chr2:38265130 C/A cg07380506 chr2:38303506 CYP1B1 -0.56 -4.98 -0.41 2.04e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs7208859 0.673 rs9909497 chr17:29173228 C/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4713118 0.662 rs9357060 chr6:28024486 C/G cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs10540 1.000 rs61876332 chr11:487101 C/T cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs9733 0.596 rs17606613 chr1:150683015 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs2204008 0.775 rs11514369 chr12:38305411 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.3e-5 Bladder cancer; TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs4660261 0.526 rs3094954 chr1:44320919 C/T cg12908607 chr1:44402522 ARTN -0.64 -7.74 -0.57 3e-12 Intelligence (multi-trait analysis); TGCT cis rs6831352 0.918 rs13127582 chr4:100058194 G/A cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.18e-6 Alcohol dependence; TGCT cis rs875971 0.862 rs6978028 chr7:65886300 G/C cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs9329289 0.851 rs61835719 chr10:2543390 A/G cg15501526 chr10:2543763 NA 0.39 4.87 0.4 3.32e-6 Age-related hearing impairment; TGCT cis rs1371867 0.846 rs1660329 chr8:101304048 G/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs2455799 0.613 rs2470536 chr3:15715156 G/C cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.65e-6 Mean platelet volume; TGCT cis rs12762955 0.507 rs7095853 chr10:1040798 T/C cg20503657 chr10:835505 NA -0.42 -5.31 -0.43 4.8e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg12311346 chr5:56204834 C5orf35 -0.78 -6.56 -0.51 1.32e-9 Initial pursuit acceleration; TGCT cis rs3008870 0.628 rs2755257 chr1:67515309 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.73 7.1 0.54 8.47e-11 Lymphocyte percentage of white cells; TGCT cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg22963979 chr7:1858916 MAD1L1 -0.37 -5.9 -0.47 3.17e-8 Bipolar disorder and schizophrenia; TGCT cis rs28595532 0.920 rs115744897 chr4:119749064 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs3784262 0.669 rs4646642 chr15:58246916 A/G cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.27 -0.49 5.41e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs8064299 0.574 rs12452204 chr17:72774128 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.92 10.38 0.68 1.49e-18 Monocyte count; TGCT cis rs9952991 0.941 rs2542151 chr18:12779947 G/T cg23544223 chr18:12777786 NA 0.63 6.1 0.48 1.24e-8 Inflammatory skin disease; TGCT cis rs9295536 0.676 rs7743854 chr6:22122389 A/G cg25792714 chr6:21666554 FLJ22536 -0.52 -4.63 -0.38 9.17e-6 Neuroblastoma; TGCT cis rs832540 1.000 rs192249 chr5:56197514 C/G cg12311346 chr5:56204834 C5orf35 -0.51 -5.38 -0.44 3.54e-7 Coronary artery disease; TGCT cis rs4746818 1.000 rs9299502 chr10:70876934 C/T cg11621586 chr10:70884670 VPS26A 1.22 11.35 0.71 6.63e-21 Left atrial antero-posterior diameter; TGCT cis rs763014 0.931 rs710925 chr16:633354 G/A cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg04267008 chr7:1944627 MAD1L1 -0.42 -5.58 -0.45 1.46e-7 Bipolar disorder and schizophrenia; TGCT cis rs3796352 1.000 rs7622420 chr3:53111069 A/G cg27565382 chr3:53032988 SFMBT1 0.44 5.31 0.43 4.91e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7552404 1.000 rs211718 chr1:76106675 C/T cg22875332 chr1:76189707 ACADM 0.77 9.38 0.64 4.01e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2730260 0.537 rs55864635 chr7:158859744 C/T cg27122614 chr7:157913741 PTPRN2 0.43 4.45 0.37 1.87e-5 Myopia (pathological); TGCT cis rs739496 0.843 rs10774629 chr12:112020214 G/C cg10833066 chr12:111807467 FAM109A -0.37 -5.2 -0.42 8.01e-7 Platelet count; TGCT cis rs523522 0.962 rs4766969 chr12:120988238 A/G cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs6598955 0.670 rs11247892 chr1:26592727 A/G cg04990556 chr1:26633338 UBXN11 -0.91 -11.45 -0.72 3.65e-21 Obesity-related traits; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg11905131 chr22:24372483 LOC391322 -0.98 -12.39 -0.74 1.97e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7246657 0.722 rs1564206 chr19:38040076 C/T cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs12579753 0.827 rs7958100 chr12:82200782 G/A cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs12510870 0.599 rs12506675 chr4:74449853 T/C cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs887829 0.569 rs4124874 chr2:234665659 T/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.51 -0.38 1.46e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg06634786 chr22:41940651 POLR3H -0.85 -7.8 -0.57 2.16e-12 Vitiligo; TGCT cis rs10927875 0.541 rs1739840 chr1:16342237 A/G cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs11650494 0.908 rs11650087 chr17:47362923 T/A cg08112188 chr17:47440006 ZNF652 1.05 5.4 0.44 3.32e-7 Prostate cancer; TGCT cis rs1355223 0.583 rs2956074 chr11:34864880 T/C cg24088639 chr11:34937564 PDHX;APIP -0.51 -4.64 -0.38 8.76e-6 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs1018836 0.923 rs7840846 chr8:91565501 T/A cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs739496 0.579 rs6489817 chr12:112291242 A/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs6459680 0.723 rs7793415 chr7:156258646 C/T cg02321112 chr7:156810523 NA -0.34 -4.81 -0.4 4.34e-6 Glomerular filtration rate (creatinine); TGCT cis rs12983728 1.000 rs12983728 chr19:58671267 G/A cg07378217 chr19:58662286 ZNF329 -0.83 -4.69 -0.39 6.97e-6 Cholesterol, total; TGCT cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg10411590 chr13:21900810 NA 0.38 5.06 0.41 1.48e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg10047753 chr17:41438598 NA 0.96 9.49 0.65 2.15e-16 Menopause (age at onset); TGCT cis rs6570726 0.689 rs411785 chr6:145888398 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT trans rs9388451 0.839 rs9321054 chr6:126079968 A/G cg05039488 chr6:79577232 IRAK1BP1 0.74 8.58 0.61 3.3e-14 Brugada syndrome; TGCT cis rs9896933 0.778 rs80112422 chr17:80827719 G/T cg20578329 chr17:80767326 TBCD -0.33 -4.67 -0.39 7.66e-6 Bone mineral accretion in asthma (oral corticosteroid dose interaction); TGCT cis rs6938 0.618 rs12912839 chr15:75221245 C/T cg09165964 chr15:75287851 SCAMP5 0.55 5.03 0.41 1.67e-6 Breast cancer; TGCT cis rs7937682 0.924 rs7924683 chr11:111555796 C/A cg09085632 chr11:111637200 PPP2R1B -1.11 -11.61 -0.72 1.55e-21 Primary sclerosing cholangitis; TGCT cis rs9611565 0.649 rs139540 chr22:42178040 C/T cg03806693 chr22:41940476 POLR3H -0.95 -9.22 -0.64 9.83e-16 Vitiligo; TGCT cis rs6016142 0.759 rs292858 chr20:38333579 A/G cg22128431 chr20:37434409 PPP1R16B 0.6 4.62 0.38 9.48e-6 Estradiol levels;Dupuytren's disease; TGCT cis rs1005277 0.505 rs1208689 chr10:38097775 C/G cg25427524 chr10:38739819 LOC399744 -0.37 -7.41 -0.55 1.75e-11 Extrinsic epigenetic age acceleration; TGCT cis rs1153858 1.000 rs1288775 chr15:45661678 T/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg24829409 chr8:58192753 C8orf71 -0.52 -5.02 -0.41 1.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs2288884 1.000 rs58817690 chr19:52536692 C/T cg13540795 chr19:52551618 ZNF432 -0.57 -4.9 -0.4 2.97e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs11785400 0.793 rs4301430 chr8:143737416 A/G cg10596483 chr8:143751796 JRK 0.55 5.43 0.44 2.91e-7 Schizophrenia; TGCT cis rs478304 0.514 rs75601653 chr11:65483370 C/G cg17480646 chr11:65405466 SIPA1 -0.58 -6.56 -0.51 1.34e-9 Acne (severe); TGCT cis rs425277 0.585 rs3107156 chr1:2060630 T/C cg03732007 chr1:2071316 PRKCZ -0.28 -6.39 -0.5 3.11e-9 Height; TGCT cis rs57590327 0.503 rs9874184 chr3:81505439 C/T cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs6754311 0.517 rs1469996 chr2:136542560 A/G cg07169764 chr2:136633963 MCM6 0.89 7.81 0.57 2.05e-12 Mosquito bite size; TGCT cis rs644799 1.000 rs472231 chr11:95532166 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.58 0.69 4.97e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6570726 0.791 rs441290 chr6:145883183 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.86 0.4 3.43e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7954584 0.531 rs6486781 chr12:122318985 A/C cg21171335 chr12:122356390 WDR66 0.57 6.07 0.48 1.43e-8 Mean corpuscular volume; TGCT cis rs9916302 0.904 rs6503503 chr17:37514373 G/A cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs7260538 0.808 rs707265 chr19:41524087 A/G cg20630647 chr19:41531805 NA 0.32 5.07 0.41 1.41e-6 DDT metabolite (p,p'-DDE levels); TGCT cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs9549367 0.789 rs7994324 chr13:113906497 T/C cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs7095607 0.813 rs7903493 chr10:69931156 C/A cg18986048 chr10:69913749 MYPN 0.46 5.24 0.43 6.63e-7 Lung function (FVC); TGCT cis rs7552404 0.924 rs7550974 chr1:76204185 A/G cg22875332 chr1:76189707 ACADM 0.77 9.49 0.65 2.13e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3947 1.000 rs1736082 chr8:11703420 C/T cg02840367 chr8:11660030 FDFT1 0.91 6.66 0.51 7.98e-10 Blood protein levels; TGCT cis rs7267979 0.586 rs11087505 chr20:25196520 T/A cg03522245 chr20:25566470 NINL 0.49 5.17 0.42 9.26e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9811920 0.732 rs793446 chr3:99578114 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.2 0.42 7.93e-7 Axial length; TGCT cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg11494091 chr17:61959527 GH2 0.43 7.3 0.55 3.05e-11 Height; TGCT cis rs6860806 0.661 rs334902 chr5:131586559 C/G cg24060327 chr5:131705240 SLC22A5 -0.59 -5.9 -0.47 3.16e-8 Breast cancer; TGCT cis rs6952808 0.656 rs12699646 chr7:2093162 T/G cg04267008 chr7:1944627 MAD1L1 0.41 5.36 0.43 3.96e-7 Bipolar disorder and schizophrenia; TGCT cis rs6964587 0.900 rs11984136 chr7:91766953 T/C cg22709100 chr7:91322751 NA 0.28 4.44 0.37 1.96e-5 Breast cancer; TGCT cis rs7100689 0.577 rs10788545 chr10:82034675 A/G cg01528321 chr10:82214614 TSPAN14 0.7 6.78 0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs861020 0.563 rs35898529 chr1:210053096 G/A cg05527609 chr1:210001259 C1orf107 -0.96 -7.33 -0.55 2.65e-11 Orofacial clefts; TGCT cis rs11673344 0.523 rs1667379 chr19:37492094 A/T cg08039142 chr19:36980659 ZNF566 0.59 5.58 0.45 1.41e-7 Obesity-related traits; TGCT cis rs807669 0.903 rs756651 chr22:19179367 T/C cg02655711 chr22:19163373 SLC25A1 0.42 9.92 0.67 1.94e-17 Metabolite levels; TGCT cis rs10493773 1.000 rs7523292 chr1:86134992 A/G cg17807903 chr1:86174739 ZNHIT6 -0.37 -4.69 -0.39 7.01e-6 Urate levels in overweight individuals; TGCT cis rs35146811 0.700 rs858513 chr7:99825558 G/A cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg26566898 chr11:117069891 TAGLN 0.35 5.09 0.42 1.27e-6 Blood protein levels; TGCT cis rs3540 0.513 rs1072879 chr15:90922038 C/T cg22089800 chr15:90895588 ZNF774 0.82 9.09 0.63 2.03e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2404602 0.647 rs11629727 chr15:77009038 G/C cg22467129 chr15:76604101 ETFA 0.47 4.7 0.39 6.84e-6 Blood metabolite levels; TGCT cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT trans rs1814175 0.817 rs2866863 chr11:49953242 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs12477438 0.748 rs4851185 chr2:99666497 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs6121246 0.529 rs6060195 chr20:30185638 C/T cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs3087591 0.708 rs2525568 chr17:29675878 T/G cg24425628 chr17:29625626 OMG;NF1 0.38 5.5 0.44 2.09e-7 Hip circumference; TGCT cis rs2204008 0.571 rs7970136 chr12:38531951 G/C cg26384229 chr12:38710491 ALG10B -0.53 -4.78 -0.39 4.9100000000000004e-06 Bladder cancer; TGCT cis rs11874712 1.000 rs7235373 chr18:43653763 C/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.54 5.28 0.43 5.47e-7 Migraine - clinic-based; TGCT cis rs12360000 0.864 rs34695673 chr10:1907540 G/T cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs1552244 0.706 rs279545 chr3:9972493 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -5.8 -0.46 5.09e-8 Alzheimer's disease; TGCT cis rs7267979 0.903 rs6050481 chr20:25224580 C/T cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8084125 0.832 rs62105175 chr18:74948498 T/C cg05528293 chr18:74961138 GALR1 0.52 5.2 0.42 8.04e-7 Obesity-related traits; TGCT cis rs2594989 0.943 rs2454492 chr3:11507793 G/A cg26283222 chr3:11613257 VGLL4 -0.22 -4.53 -0.38 1.36e-5 Circulating chemerin levels; TGCT cis rs3791556 0.898 rs3791549 chr2:240109024 A/G cg03281426 chr2:240109471 HDAC4 -0.28 -4.59 -0.38 1.08e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9368481 0.678 rs62402024 chr6:26923976 T/C cg26531700 chr6:26746687 NA 0.69 6.41 0.5 2.71e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs34779708 0.931 rs79749947 chr10:35277081 A/T cg04310649 chr10:35416472 CREM -0.51 -4.55 -0.38 1.24e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7267979 1.000 rs4815420 chr20:25383979 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12220898 0.749 rs7098191 chr10:50481213 A/G cg09603381 chr10:49954066 WDFY4 0.39 4.48 0.37 1.68e-5 Inflammatory biomarkers; TGCT cis rs17270561 0.943 rs4478398 chr6:25694684 T/C cg17042849 chr6:26104293 HIST1H4C -0.69 -4.48 -0.37 1.64e-5 Iron status biomarkers; TGCT cis rs7914558 1.000 rs8139 chr10:104848123 G/A cg04362960 chr10:104952993 NT5C2 0.62 5.5 0.44 2.09e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg05785598 chr3:49045655 WDR6 0.36 4.86 0.4 3.41e-6 Menarche (age at onset); TGCT cis rs13242816 1.000 rs34228114 chr7:116106986 C/T cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT cis rs986417 0.892 rs8010656 chr14:60797112 G/A cg27398547 chr14:60952738 C14orf39 -1.56 -6.75 -0.52 5.13e-10 Gut microbiota (bacterial taxa); TGCT cis rs11105298 0.891 rs10777184 chr12:89919568 C/T cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT trans rs7819412 0.775 rs6601564 chr8:10982051 A/G cg06636001 chr8:8085503 FLJ10661 -0.74 -6.85 -0.52 3.12e-10 Triglycerides; TGCT cis rs921968 0.643 rs552882 chr2:219401726 G/A cg02176678 chr2:219576539 TTLL4 0.44 6.34 0.49 3.92e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs7582180 0.790 rs13020451 chr2:100927131 T/G cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs2282802 0.685 rs4913079 chr5:139683029 A/G cg01081189 chr5:139537190 NA 0.29 5.31 0.43 5e-7 Intelligence (multi-trait analysis); TGCT cis rs7264396 0.676 rs6060729 chr20:34557004 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg01802117 chr1:53393560 SCP2 -0.39 -4.61 -0.38 1e-5 Monocyte count; TGCT cis rs4073582 0.555 rs521109 chr11:66030948 G/A cg16950941 chr11:66035639 RAB1B 0.58 5.44 0.44 2.67e-7 Gout; TGCT cis rs4711350 0.749 rs7752348 chr6:33718252 C/G cg18005901 chr6:33739558 LEMD2 -0.58 -6.4 -0.5 2.89e-9 Schizophrenia; TGCT cis rs73001065 0.901 rs17217098 chr19:19702384 G/A cg03709012 chr19:19516395 GATAD2A 1.25 5.58 0.45 1.43e-7 LDL cholesterol; TGCT cis rs4665809 1.000 rs6749855 chr2:26255263 A/G cg04944784 chr2:26401820 FAM59B -0.69 -6.23 -0.49 6.54e-9 Gut microbiome composition (summer); TGCT cis rs9952991 0.566 rs484020 chr18:12855440 G/A cg23598886 chr18:12777645 NA 0.55 4.77 0.39 5.06e-6 Inflammatory skin disease; TGCT cis rs6582630 0.537 rs2204006 chr12:38407098 A/G cg13010199 chr12:38710504 ALG10B 0.55 4.46 0.37 1.84e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs782590 0.967 rs62165172 chr2:55736237 A/G cg03859395 chr2:55845619 SMEK2 0.92 11.31 0.71 8e-21 Metabolic syndrome; TGCT cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.05 0.41 1.51e-6 Menopause (age at onset); TGCT cis rs17376456 1.000 rs17323433 chr5:93551028 G/A cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.96e-12 Diabetic retinopathy; TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg19723775 chr5:179050963 HNRNPH1 -0.54 -5.47 -0.44 2.43e-7 Lung cancer; TGCT cis rs7772486 0.754 rs1415746 chr6:146077107 A/G cg05347473 chr6:146136440 FBXO30 -0.54 -5.03 -0.41 1.65e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4820539 1.000 rs3827316 chr22:23468538 T/C cg14186256 chr22:23484241 RTDR1 0.98 11.82 0.73 4.6e-22 Bone mineral density; TGCT cis rs7937682 0.632 rs4936800 chr11:111734097 T/A cg09085632 chr11:111637200 PPP2R1B 0.88 8.47 0.61 5.93e-14 Primary sclerosing cholangitis; TGCT cis rs17221829 0.644 rs72971008 chr11:89358706 G/A cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs9972944 0.729 rs1541610 chr17:63773836 C/T cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs13191362 1.000 rs34228197 chr6:163008232 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2832191 0.716 rs1984012 chr21:30392472 T/C cg24692254 chr21:30365293 RNF160 0.97 11.38 0.71 5.5e-21 Dental caries; TGCT cis rs3617 0.573 rs62253583 chr3:52928334 G/A cg10802521 chr3:52805072 NEK4 0.58 6.62 0.51 9.63e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs12510870 0.599 rs3756073 chr4:74413589 A/G cg05868023 chr4:75230803 EREG -0.53 -4.63 -0.38 9.08e-6 Iris color (b* coordinate); TGCT cis rs3733585 0.806 rs7375599 chr4:9954918 C/T cg00071950 chr4:10020882 SLC2A9 0.65 8.21 0.59 2.4e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.830 rs10049985 chr4:99023517 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.791 rs1967978 chr4:98966152 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.54 0.56 8.74e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs941873 0.836 rs6480931 chr10:81108482 T/C cg09469691 chr10:81107165 PPIF 0.54 5.37 0.43 3.75e-7 Height; TGCT cis rs8056742 0.730 rs13335706 chr16:85091957 T/A cg00229868 chr16:85520891 NA 0.33 4.97 0.41 2.18e-6 Amyotrophic lateral sclerosis; TGCT cis rs7917772 0.503 rs11191320 chr10:104293394 T/C cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs941408 1.000 rs2741990 chr19:2796644 C/T cg22153745 chr1:153894579 GATAD2B -0.64 -7.15 -0.54 6.54e-11 Total cholesterol levels; TGCT cis rs7619833 0.607 rs7634878 chr3:27241219 C/T cg02860705 chr3:27208620 NA 0.26 4.44 0.37 1.94e-5 Breast cancer; TGCT cis rs732765 0.734 rs1057500 chr14:75205116 G/A cg06637938 chr14:75390232 RPS6KL1 -0.57 -5.03 -0.41 1.69e-6 Non-small cell lung cancer; TGCT cis rs2013441 1.000 rs2703782 chr17:20144799 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs6940638 0.688 rs9461335 chr6:27138529 C/A cg26531700 chr6:26746687 NA -0.53 -4.6 -0.38 1.04e-5 Intelligence (multi-trait analysis); TGCT trans rs7618501 1.000 rs34451146 chr3:49813013 C/T cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs3734573 chr6:28059437 T/C cg12963246 chr6:28129442 ZNF389 0.5 4.93 0.4 2.63e-6 Depression; TGCT cis rs6701037 0.748 rs11583687 chr1:175132049 A/C cg00321850 chr1:175162397 KIAA0040 0.39 5.47 0.44 2.38e-7 Alcohol dependence; TGCT cis rs10504229 0.861 rs67966192 chr8:58188172 A/C cg24829409 chr8:58192753 C8orf71 -0.51 -5.08 -0.42 1.32e-6 Developmental language disorder (linguistic errors); TGCT cis rs367943 1.000 rs348931 chr5:112812864 G/C cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs3733585 0.699 rs62294332 chr4:9959989 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6669919 0.647 rs10863900 chr1:211675597 A/G cg26515805 chr1:211431828 RCOR3 -0.5 -5.12 -0.42 1.14e-6 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs516425 chr11:68715675 G/A cg06112835 chr11:68658793 MRPL21 0.46 7.86 0.58 1.56e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs8031584 0.678 rs3122 chr15:31170290 A/T cg08109568 chr15:31115862 NA 0.4 5.04 0.41 1.62e-6 Huntington's disease progression; TGCT cis rs10114408 0.959 rs7863529 chr9:96639160 T/G cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg27588902 chr6:42928151 GNMT -0.56 -6.87 -0.53 2.77e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6089829 0.925 rs13041507 chr20:61666180 T/C cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT trans rs57221529 0.709 rs72707024 chr5:667915 G/A cg25482853 chr8:67687455 SGK3 1.22 10.55 0.69 5.87e-19 Lung disease severity in cystic fibrosis; TGCT cis rs2658782 0.724 rs2248020 chr11:93259965 A/C cg15737290 chr11:93063684 CCDC67 0.71 5.32 0.43 4.73e-7 Pulmonary function decline; TGCT cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg03806693 chr22:41940476 POLR3H -1.11 -11.64 -0.72 1.26e-21 Vitiligo; TGCT cis rs13191362 1.000 rs66789102 chr6:163104432 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.96 7.87 0.58 1.5e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs62380364 0.507 rs34321 chr5:88020319 C/G cg24804195 chr5:87968844 LOC645323 -0.59 -5.92 -0.47 2.9e-8 Intelligence (multi-trait analysis); TGCT cis rs78456975 1.000 rs6708604 chr2:1556887 C/T cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs151227923 1 rs151227923 chr7:155106564 C/T cg04811098 chr7:155088454 INSIG1 0.32 4.96 0.41 2.23e-6 Stem cell growth factor beta levels; TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg07167872 chr1:205819463 PM20D1 0.57 7.37 0.55 2.12e-11 Menarche (age at onset); TGCT cis rs6424115 0.729 rs586173 chr1:24055718 A/G cg15997130 chr1:24165203 NA -0.69 -6.59 -0.51 1.12e-9 Immature fraction of reticulocytes; TGCT cis rs4474742 1 rs4474742 chr17:28065578 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -7.97 -0.58 8.91e-13 Monocyte count; TGCT cis rs9467773 1.000 rs9393728 chr6:26509330 C/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs2268241 0.877 rs17885509 chr21:34779630 C/T cg14850771 chr21:34775459 IFNGR2 0.61 5.23 0.43 6.88e-7 Obesity-related traits; TGCT cis rs617219 0.710 rs6874525 chr5:78574237 C/T cg09550809 chr5:78407562 BHMT -0.37 -5.24 -0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs922182 0.542 rs7179912 chr15:64263854 C/T cg02919090 chr15:64263738 DAPK2 0.36 6.87 0.53 2.76e-10 Blood protein levels; TGCT cis rs734999 0.566 rs4648563 chr1:2536002 C/G cg18854424 chr1:2615690 NA 0.43 4.96 0.41 2.31e-6 Ulcerative colitis; TGCT cis rs13022357 0.826 rs6720840 chr2:160087815 T/C cg00168785 chr2:160142643 WDSUB1 0.46 4.6 0.38 1.04e-5 Sudden cardiac arrest; TGCT cis rs2729354 1.000 rs2729355 chr11:57353983 T/G cg24343310 chr11:57249947 NA 0.28 4.8 0.4 4.5e-6 Blood protein levels; TGCT cis rs17221829 0.965 rs10830366 chr11:89459254 C/T cg02982614 chr11:89391479 FOLH1B -0.27 -4.71 -0.39 6.47e-6 Anxiety in major depressive disorder; TGCT cis rs12477438 0.520 rs1453563 chr2:99720267 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs7666738 0.570 rs1869351 chr4:99077286 T/C cg05340658 chr4:99064831 C4orf37 0.44 4.77 0.39 5.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs709400 0.633 rs10143247 chr14:103920927 G/A cg26031613 chr14:104095156 KLC1 0.84 9.43 0.65 2.98e-16 Body mass index; TGCT cis rs9394169 1.000 rs9394169 chr6:33778964 A/G cg13859433 chr6:33739653 LEMD2 -0.27 -4.72 -0.39 6.19e-6 Essential tremor; TGCT cis rs2439831 0.702 rs3759791 chr15:44090798 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.01 0.47 1.91e-8 Lung cancer in ever smokers; TGCT cis rs7089973 0.604 rs11196924 chr10:116571796 A/C cg03647239 chr10:116582469 FAM160B1 -0.56 -5.15 -0.42 9.97e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs6546847 0.531 rs2567601 chr2:73985167 T/G cg07208825 chr2:73871855 ALMS1P 0.29 5.27 0.43 5.73e-7 Urinary metabolites (H-NMR features); TGCT cis rs763121 0.853 rs1056610 chr22:39080078 C/T cg06022373 chr22:39101656 GTPBP1 -0.75 -7.78 -0.57 2.41e-12 Menopause (age at onset); TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg15242686 chr22:24348715 GSTTP1 0.42 5.66 0.45 1.01e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2637266 1.000 rs7905033 chr10:78368212 A/C cg18941641 chr10:78392320 NA 0.4 4.69 0.39 6.99e-6 Pulmonary function; TGCT cis rs9911578 1.000 rs6503870 chr17:56659018 C/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs4273100 0.512 rs7502682 chr17:19295450 G/T cg03910582 chr17:19030146 GRAPL -0.45 -6.22 -0.49 6.97e-9 Schizophrenia; TGCT cis rs950776 0.616 rs6495307 chr15:78890321 C/T cg06917634 chr15:78832804 PSMA4 0.65 5.3 0.43 5.01e-7 Sudden cardiac arrest; TGCT cis rs6598955 0.694 rs4659416 chr1:26580937 T/G cg04990556 chr1:26633338 UBXN11 -0.91 -11.45 -0.72 3.65e-21 Obesity-related traits; TGCT cis rs797680 0.856 rs12030549 chr1:93669218 T/C cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.42 7.05e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs17253792 0.822 rs74412558 chr14:56054311 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7542091 0.748 rs2357231 chr1:210028454 A/C cg21951975 chr1:209979733 IRF6 -0.44 -4.62 -0.38 9.39e-6 Monobrow; TGCT cis rs4689592 0.503 rs56099074 chr4:7071259 A/G cg25660036 chr4:7070649 GRPEL1 0.59 4.73 0.39 5.9e-6 Monocyte percentage of white cells; TGCT trans rs877282 0.945 rs11253398 chr10:790012 T/C cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs9534288 0.659 rs1581846 chr13:46650686 G/A cg15192986 chr13:46630673 CPB2 -0.53 -6.66 -0.51 8.13e-10 Blood protein levels; TGCT cis rs2229238 0.866 rs59741504 chr1:154504601 T/C cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs4132509 0.739 rs10927033 chr1:243695539 C/A cg21452805 chr1:244014465 NA 0.75 4.55 0.38 1.28e-5 RR interval (heart rate); TGCT cis rs11264213 0.901 rs72661608 chr1:36333850 C/G cg27506609 chr1:36549197 TEKT2 0.42 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs4767364 0.796 rs4767293 chr12:112463296 A/G cg10833066 chr12:111807467 FAM109A 0.34 5.53 0.44 1.78e-7 Oral cavity and pharyngeal cancer; TGCT cis rs7104764 1.000 rs7482591 chr11:245861 G/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs9291683 0.551 rs2276961 chr4:10022981 C/T cg11266682 chr4:10021025 SLC2A9 0.68 9.96 0.67 1.58e-17 Bone mineral density; TGCT cis rs9916302 0.821 rs1966915 chr17:37425262 A/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT trans rs877282 0.842 rs35872126 chr10:764545 G/A cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs7659604 0.539 rs7686200 chr4:122764553 C/T cg06713675 chr4:122721982 EXOSC9 -0.68 -9.18 -0.64 1.23e-15 Type 2 diabetes; TGCT cis rs7552404 0.924 rs3818855 chr1:76198785 C/T cg10523679 chr1:76189770 ACADM 0.89 9.85 0.66 2.9e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9911578 0.967 rs7503190 chr17:57184162 A/C cg05425664 chr17:57184151 TRIM37 -0.68 -6.9 -0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs12579753 0.871 rs12822050 chr12:82183041 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs9527 0.615 rs3897401 chr10:104696379 T/C cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs9894429 0.700 rs113915083 chr17:79552696 G/C cg21028142 chr17:79581711 NPLOC4 -0.3 -6.96 -0.53 1.79e-10 Eye color traits; TGCT cis rs7095607 0.967 rs3956959 chr10:69964861 T/C cg18986048 chr10:69913749 MYPN 0.43 4.45 0.37 1.92e-5 Lung function (FVC); TGCT cis rs2840044 1.000 rs1671656 chr17:33939661 C/T cg05299278 chr17:33885742 SLFN14 0.23 5.07 0.41 1.38e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs11247915 0.600 rs3795686 chr1:26582091 G/A cg23732845 chr1:26663426 AIM1L -0.34 -4.5 -0.37 1.53e-5 Obesity-related traits; TGCT cis rs11696501 0.688 rs4810465 chr20:44311354 A/G cg11783356 chr20:44313418 WFDC10B 0.33 4.49 0.37 1.6e-5 Brain structure; TGCT cis rs7819412 0.807 rs10105315 chr8:10932203 G/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.55 -0.38 1.24e-5 Triglycerides; TGCT cis rs17076896 0.786 rs61956075 chr13:19931905 G/C cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs597539 0.652 rs559032 chr11:68710847 G/T cg04772025 chr11:68637568 NA 0.63 7.15 0.54 6.66e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1005277 0.579 rs1740732 chr10:38491385 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.25 -0.6 2e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7772486 0.875 rs11155452 chr6:146424631 C/T cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.525 rs1335644 chr6:8488041 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9399137 0.507 rs7748708 chr6:135275142 G/A cg24558204 chr6:135376177 HBS1L 0.49 4.96 0.41 2.24e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs6876348 0.598 rs2577539 chr5:128301211 A/G cg25555059 chr5:128301488 SLC27A6 -0.29 -4.72 -0.39 6.18e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9902453 0.845 rs58575982 chr17:28221776 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 7.06 0.54 1.04e-10 Coffee consumption (cups per day); TGCT cis rs4851254 0.517 rs13020141 chr2:100653842 G/A cg22139774 chr2:100720529 AFF3 -0.45 -4.9 -0.4 2.94e-6 Intelligence (multi-trait analysis); TGCT cis rs9911578 1.000 rs2531734 chr17:56550804 T/C cg05425664 chr17:57184151 TRIM37 0.63 6.21 0.49 7.48e-9 Intelligence (multi-trait analysis); TGCT cis rs1538970 0.962 rs3219472 chr1:45804050 A/G cg05343316 chr1:45956843 TESK2 -0.63 -5.06 -0.41 1.45e-6 Platelet count; TGCT cis rs7666738 0.830 rs10001479 chr4:98918764 A/G cg18180107 chr4:99064573 C4orf37 -0.53 -4.81 -0.4 4.28e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs9393025 chr6:8490618 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7178572 0.633 rs11854328 chr15:77840129 A/G cg22256960 chr15:77711686 NA -0.81 -7.65 -0.57 4.82e-12 Type 2 diabetes; TGCT cis rs35146811 0.625 rs2906645 chr7:99817859 A/G cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs7208859 0.524 rs60114476 chr17:29097667 A/T cg13385521 chr17:29058706 SUZ12P 0.81 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7917772 0.619 rs2801050 chr10:104509393 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.66 5.42 0.44 2.94e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2439831 0.681 rs526450 chr15:43599325 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.94 6.62 0.51 9.66e-10 Lung cancer in ever smokers; TGCT cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg07507251 chr3:52567010 NT5DC2 0.5 7.16 0.54 6.19e-11 Bipolar disorder; TGCT trans rs1005277 0.579 rs2472173 chr10:38374638 G/A cg27523141 chr10:43048294 ZNF37B 0.73 8.4 0.6 8.55e-14 Extrinsic epigenetic age acceleration; TGCT trans rs208520 0.565 rs1385222 chr6:66753013 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.06 14.91 0.8 1.98e-29 Exhaled nitric oxide output; TGCT cis rs4665809 0.877 rs35224700 chr2:26298037 T/C cg25036284 chr2:26402008 FAM59B 0.58 4.58 0.38 1.12e-5 Gut microbiome composition (summer); TGCT cis rs2658782 0.950 rs2446061 chr11:93149277 C/T cg15737290 chr11:93063684 CCDC67 0.82 5.67 0.45 9.52e-8 Pulmonary function decline; TGCT cis rs3617 0.625 rs2336558 chr3:52886240 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.73 0.39 6.09e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs2180341 0.960 rs9401952 chr6:127677027 A/C cg24812749 chr6:127587940 RNF146 0.93 7.4 0.55 1.83e-11 Breast cancer; TGCT cis rs1355223 0.583 rs2956074 chr11:34864880 T/C cg11058730 chr11:34937778 PDHX;APIP 0.75 8.24 0.59 2.05e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs6570726 0.791 rs418701 chr6:145889992 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9640161 0.750 rs3735167 chr7:150039555 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.59 0.38 1.09e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs8031584 0.697 rs798080 chr15:31122169 T/C cg08109568 chr15:31115862 NA 0.39 5.22 0.42 7.26e-7 Huntington's disease progression; TGCT cis rs7246657 0.722 rs2287229 chr19:38188652 G/A cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs17270561 0.887 rs9358870 chr6:25719210 T/C cg16482183 chr6:26056742 HIST1H1C 0.71 4.82 0.4 4.1e-6 Iron status biomarkers; TGCT cis rs17376456 0.757 rs1031424 chr5:93139706 G/C cg25358565 chr5:93447407 FAM172A 0.9 7.6 0.56 6.43e-12 Diabetic retinopathy; TGCT cis rs2836950 0.501 rs11088470 chr21:40689162 A/G cg11890956 chr21:40555474 PSMG1 -0.66 -6.24 -0.49 6.47e-9 Menarche (age at onset); TGCT trans rs10504390 0.585 rs117486340 chr8:66542077 G/A cg18118147 chr19:51128640 SYT3 -0.77 -6.85 -0.52 2.99e-10 IgG glycosylation; TGCT cis rs6840360 0.967 rs10776524 chr4:152602585 G/A cg17479576 chr4:152424074 FAM160A1 -0.52 -5.66 -0.45 9.86e-8 Intelligence (multi-trait analysis); TGCT cis rs6964587 1.000 rs12540565 chr7:91633213 T/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs7095607 0.693 rs7896727 chr10:69952376 C/T cg18986048 chr10:69913749 MYPN 0.58 6.79 0.52 4.14e-10 Lung function (FVC); TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg04025307 chr7:1156635 C7orf50 0.21 4.97 0.41 2.18e-6 Longevity;Endometriosis; TGCT cis rs910316 1.000 rs12879542 chr14:75507525 C/T cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.97e-11 Height; TGCT cis rs34816374 1 rs34816374 chr6:26949672 A/G cg16898833 chr6:26189333 HIST1H4D 1.28 6.15 0.48 9.89e-9 Lung cancer in ever smokers; TGCT cis rs6060717 0.654 rs6060686 chr20:34512606 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.69 -0.39 6.98e-6 Hip circumference adjusted for BMI; TGCT trans rs8073060 0.586 rs226090 chr17:34034059 C/T cg19694781 chr19:47549865 TMEM160 -0.61 -13.57 -0.77 2.84e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9640161 0.789 rs1047207 chr7:150037660 A/G cg10018233 chr7:150070692 REPIN1 0.33 4.95 0.41 2.4e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs3849570 0.961 rs11915042 chr3:81834060 G/A cg07356753 chr3:81810745 GBE1 -0.82 -7.62 -0.56 5.6e-12 Waist circumference;Body mass index; TGCT cis rs9633740 1.000 rs7900536 chr10:82253701 G/T cg01528321 chr10:82214614 TSPAN14 1.03 8.56 0.61 3.66e-14 Post bronchodilator FEV1; TGCT cis rs72781680 0.898 rs72780191 chr2:24007122 T/C cg08917208 chr2:24149416 ATAD2B 0.93 5.84 0.46 4.22e-8 Lymphocyte counts; TGCT cis rs1775715 0.966 rs1755067 chr10:32296195 C/T cg14930904 chr10:32216787 ARHGAP12 -0.52 -4.87 -0.4 3.27e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs9303401 0.614 rs3803752 chr17:56540267 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.22 0.49 6.83e-9 Cognitive test performance; TGCT cis rs13064411 0.696 rs3732803 chr3:113211957 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.64 -0.45 1.08e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT trans rs1814175 0.669 rs11040455 chr11:49669829 G/C cg15704280 chr7:45808275 SEPT13 -0.61 -7.03 -0.53 1.23e-10 Height; TGCT cis rs1670533 1.000 rs688785 chr4:1082707 G/C cg27284194 chr4:1044797 NA 0.69 5.93 0.47 2.78e-8 Recombination rate (females); TGCT cis rs10504229 0.817 rs55891651 chr8:58167600 C/T cg22535103 chr8:58192502 C8orf71 -0.35 -4.61 -0.38 1e-5 Developmental language disorder (linguistic errors); TGCT cis rs56104184 0.830 rs73061617 chr19:49350984 G/A cg21252483 chr19:49399788 TULP2 -0.43 -5.49 -0.44 2.2e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9972944 0.756 rs11870607 chr17:63773122 A/G cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs12643440 0.538 rs981886 chr4:17136883 T/C cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs526231 0.819 rs366437 chr5:102605601 T/C cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs7975161 0.786 rs10861181 chr12:104651110 T/C cg25273343 chr12:104657179 TXNRD1 -0.34 -5.21 -0.42 7.61e-7 Toenail selenium levels; TGCT cis rs10504229 0.683 rs949856 chr8:58144496 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs8031584 0.678 rs4779790 chr15:31164595 T/C cg08704250 chr15:31115839 NA -0.43 -6.31 -0.49 4.47e-9 Huntington's disease progression; TGCT cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg13395646 chr4:1353034 KIAA1530 -0.48 -6.33 -0.49 4.16e-9 Obesity-related traits; TGCT cis rs2439831 0.867 rs2245176 chr15:43750762 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.18 0.59 2.83e-13 Lung cancer in ever smokers; TGCT cis rs4689388 0.791 rs1046317 chr4:6304242 T/C cg14416269 chr4:6271139 WFS1 0.48 5.94 0.47 2.72e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs473651 0.935 rs558924 chr2:239339511 A/G cg18131467 chr2:239335373 ASB1 0.95 9.87 0.66 2.62e-17 Multiple system atrophy; TGCT cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs138229 0.506 rs9628282 chr22:50534952 G/T cg16473166 chr22:50639996 SELO 0.58 4.81 0.4 4.38e-6 Behavioural disinhibition (generation interaction); TGCT cis rs13217239 0.646 rs7451149 chr6:27057518 A/G cg15659132 chr6:26577336 NA -0.53 -5.31 -0.43 4.88e-7 Schizophrenia; TGCT cis rs1401999 0.966 rs4148585 chr3:183670642 A/G cg01324343 chr3:183735012 ABCC5 0.83 11.02 0.7 4.13e-20 Anterior chamber depth; TGCT cis rs3772130 0.564 rs28620947 chr3:121585631 G/A cg20356878 chr3:121714668 ILDR1 0.38 4.84 0.4 3.71e-6 Cognitive performance; TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg10819733 chr22:24237672 NA -0.3 -5.01 -0.41 1.87e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3806843 0.548 rs246052 chr5:140326413 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs526231 0.543 rs62362521 chr5:102306061 G/A cg23492399 chr5:102201601 PAM -0.53 -4.56 -0.38 1.23e-5 Primary biliary cholangitis; TGCT cis rs11671005 0.735 rs12977592 chr19:58961056 C/G cg13877915 chr19:58951672 ZNF132 0.59 5.04 0.41 1.58e-6 Mean platelet volume; TGCT cis rs6815814 0.950 rs73236615 chr4:38786869 G/T cg02016764 chr4:38805732 TLR1 -0.36 -5.46 -0.44 2.53e-7 Breast cancer; TGCT cis rs7043114 0.544 rs12335553 chr9:95297871 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.25 -0.43 6.26e-7 Height; TGCT cis rs1215050 0.755 rs1238462 chr4:98850603 A/G cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.18e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7267979 0.932 rs6037125 chr20:25463382 G/A cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6671200 1.000 rs62625008 chr1:95702582 A/G cg03123541 chr1:95699097 RWDD3 0.91 6.4 0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs2663905 1.000 rs2663905 chr15:81359137 G/A cg09888468 chr15:81410853 NA -0.66 -5.71 -0.46 8.06e-8 QT interval (drug interaction); TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg25151919 chr3:44754333 ZNF502 -0.48 -5.59 -0.45 1.38e-7 Depressive symptoms; TGCT cis rs7552404 0.961 rs17587071 chr1:76225083 A/C cg10523679 chr1:76189770 ACADM 0.92 9.51 0.65 1.94e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs669446 0.562 rs10890273 chr1:44186444 T/A cg12908607 chr1:44402522 ARTN -0.59 -6.47 -0.5 2.02e-9 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg01802117 chr1:53393560 SCP2 0.46 5.52 0.44 1.86e-7 Monocyte count; TGCT cis rs72781680 0.898 rs55761273 chr2:23957849 A/G cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs7412746 0.611 rs10888395 chr1:150762171 C/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs9814567 0.727 rs4543053 chr3:134351724 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -5.92 -0.47 2.97e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2361718 0.501 rs11869566 chr17:78143248 T/C cg09238746 chr17:78121135 EIF4A3 -1.06 -11.03 -0.7 3.89e-20 Yeast infection; TGCT cis rs2224391 0.910 rs2875979 chr6:5275243 A/T cg09085698 chr6:5261316 LYRM4;FARS2 0.74 4.79 0.4 4.58e-6 Height; TGCT cis rs4822044 0.561 rs132781 chr22:42046122 T/G cg06634786 chr22:41940651 POLR3H 0.86 7.82 0.57 1.92e-12 Cannabis dependence symptom count; TGCT cis rs732765 1.000 rs59159639 chr14:75351106 A/G cg06637938 chr14:75390232 RPS6KL1 -0.65 -5.54 -0.45 1.7e-7 Non-small cell lung cancer; TGCT cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs1532993 0.518 rs11097565 chr4:98569259 A/G cg05340658 chr4:99064831 C4orf37 -0.42 -5.05 -0.41 1.57e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs1868673 0.737 rs10154963 chr3:150169559 C/T cg24290546 chr3:150134309 TSC22D2 -0.23 -4.67 -0.39 7.69e-6 Waist circumference; TGCT cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg06697600 chr4:7070879 GRPEL1 -0.47 -4.94 -0.41 2.42e-6 Monocyte percentage of white cells; TGCT cis rs3087591 0.960 rs2905869 chr17:29519016 C/A cg24425628 chr17:29625626 OMG;NF1 0.48 7.29 0.55 3.25e-11 Hip circumference; TGCT cis rs11105298 0.891 rs10777163 chr12:89830720 T/C cg00757033 chr12:89920650 WDR51B 0.31 4.92 0.4 2.72e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6671200 1.000 rs60929805 chr1:95646386 C/T cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs6495367 1.000 rs4778634 chr15:79380822 C/T cg17916960 chr15:79447300 NA 0.38 5.29 0.43 5.46e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7727544 0.684 rs274560 chr5:131719450 T/C cg24060327 chr5:131705240 SLC22A5 0.61 6.85 0.52 3.12e-10 Blood metabolite levels; TGCT cis rs2274273 0.682 rs1187876 chr14:55495199 A/T cg01923255 chr14:55878535 KIAA0831 -0.55 -4.72 -0.39 6.29e-6 Protein biomarker; TGCT cis rs4478858 0.735 rs6679393 chr1:31770944 T/C cg07478791 chr1:31886160 SERINC2 -0.52 -5.03 -0.41 1.67e-6 Alcohol dependence; TGCT cis rs881375 0.933 rs2239657 chr9:123671520 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.39 -4.54 -0.38 1.29e-5 Rheumatoid arthritis; TGCT cis rs35146811 0.735 rs1727130 chr7:99811464 C/G cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg23248424 chr5:179741104 GFPT2 -0.38 -7.0 -0.53 1.43e-10 Height; TGCT cis rs919433 0.679 rs55656916 chr2:198519628 T/C cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs11098499 0.789 rs1980024 chr4:120253047 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs854765 0.583 rs4341796 chr17:17839024 C/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.91 0.58 1.2e-12 Total body bone mineral density; TGCT cis rs5757676 1.000 rs5757676 chr22:39841700 T/C cg05872129 chr22:39784769 NA -0.92 -7.35 -0.55 2.38e-11 IgG glycosylation; TGCT cis rs727563 0.594 rs5758408 chr22:42077737 A/C cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4689592 0.583 rs12501362 chr4:7083563 C/T cg26116260 chr4:7069785 GRPEL1 -0.84 -7.8 -0.57 2.24e-12 Monocyte percentage of white cells; TGCT cis rs2721195 0.874 rs2721173 chr8:145744429 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.89 10.08 0.67 7.89e-18 Age at first birth; TGCT cis rs2249625 0.564 rs2496496 chr6:72884053 A/G cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs208520 0.507 rs3903670 chr6:66812183 T/C cg07460842 chr6:66804631 NA -1.07 -15.45 -0.81 1.12e-30 Exhaled nitric oxide output; TGCT cis rs6089829 0.926 rs1060489 chr20:61665921 C/T cg02380750 chr20:61661411 NA 0.35 6.1 0.48 1.25e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1129187 0.702 rs2296805 chr6:42928758 T/G cg02353165 chr6:42928485 GNMT 0.8 7.05 0.54 1.09e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9308731 0.644 rs3789061 chr2:111918230 T/C cg04202892 chr2:111875749 ACOXL 0.55 6.46 0.5 2.1e-9 Chronic lymphocytic leukemia; TGCT cis rs17665859 0.844 rs76478160 chr8:446900 G/C cg17960703 chr8:356704 FBXO25 1.4 5.27 0.43 5.9e-7 Bilirubin levels; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg06675538 chr2:114033490 PAX8;LOC440839 -0.43 -4.75 -0.39 5.44e-6 Lymphocyte counts; TGCT cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs2439831 0.867 rs2920781 chr15:43924682 G/A cg19166733 chr15:44192098 FRMD5 -0.24 -4.89 -0.4 3.08e-6 Lung cancer in ever smokers; TGCT cis rs858239 0.600 rs6961131 chr7:23134790 A/G cg05602783 chr7:23145260 KLHL7 -0.64 -5.37 -0.43 3.69e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs3862030 0.500 rs11191327 chr10:104303883 T/C cg05855489 chr10:104503620 C10orf26 -0.58 -5.02 -0.41 1.73e-6 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs7208859 0.623 rs73269913 chr17:29092183 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9354352 0.791 rs4710306 chr6:66700271 A/G cg07460842 chr6:66804631 NA -0.54 -5.39 -0.44 3.38e-7 Initial pursuit acceleration in psychotic disorders; TGCT cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg20887711 chr4:1340912 KIAA1530 0.91 8.34 0.6 1.22e-13 Longevity; TGCT cis rs1218582 0.710 rs4845687 chr1:154878911 A/G cg06221963 chr1:154839813 KCNN3 -0.73 -11.82 -0.73 4.65e-22 Prostate cancer; TGCT cis rs7959452 0.536 rs4761237 chr12:69776461 C/G cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs904251 0.861 rs1757180 chr6:37486145 T/C cg25019722 chr6:37503610 NA -0.5 -6.94 -0.53 1.94e-10 Cognitive performance; TGCT cis rs7771547 0.508 rs3798471 chr6:36499571 C/T cg07856975 chr6:36356162 ETV7 0.21 4.66 0.39 7.92e-6 Platelet distribution width; TGCT cis rs1799949 0.602 rs8176235 chr17:41219560 C/T cg10047753 chr17:41438598 NA 0.79 6.59 0.51 1.13e-9 Menopause (age at onset); TGCT cis rs6546537 0.562 rs7565783 chr2:69750113 C/T cg10773587 chr2:69614142 GFPT1 -0.85 -8.68 -0.61 1.93e-14 Serum thyroid-stimulating hormone levels; TGCT cis rs10489202 0.632 rs3767476 chr1:168066940 C/T cg24449463 chr1:168025552 DCAF6 -0.55 -5.73 -0.46 7.31e-8 Schizophrenia; TGCT cis rs36229146 1 rs36229146 chr7:22784486 TTATATATAAATATATATATATATATA/T cg26061582 chr7:22766209 IL6 0.57 7.24 0.54 4.22e-11 Eosinophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs7267979 0.932 rs13040655 chr20:25582197 C/T cg14121845 chr20:25566513 NINL 0.5 5.21 0.42 7.6e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg08280861 chr8:58055591 NA 0.55 6.12 0.48 1.13e-8 Developmental language disorder (linguistic errors); TGCT cis rs9796 0.553 rs1869908 chr15:41257224 C/A cg26219294 chr15:41245916 CHAC1 -0.38 -4.53 -0.38 1.35e-5 Menopause (age at onset); TGCT cis rs11190604 1.000 rs3750630 chr10:102275780 A/G cg23241863 chr10:102295624 HIF1AN 0.7 5.39 0.44 3.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs72781680 1.000 rs55982282 chr2:24188128 G/A cg08917208 chr2:24149416 ATAD2B 0.79 4.78 0.39 4.83e-6 Lymphocyte counts; TGCT cis rs7523050 0.643 rs35885176 chr1:109401868 G/A cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs7918232 0.941 rs788220 chr10:27447205 T/C cg14442939 chr10:27389572 ANKRD26 -0.82 -5.76 -0.46 6.15e-8 Breast cancer; TGCT cis rs9309473 0.519 rs13027816 chr2:73897691 C/T cg20560298 chr2:73613845 ALMS1 0.41 4.51 0.38 1.46e-5 Metabolite levels; TGCT cis rs7508 0.511 rs2237853 chr8:17877880 G/A cg01800426 chr8:17659068 MTUS1 -0.68 -5.63 -0.45 1.14e-7 Atrial fibrillation; TGCT cis rs2576037 0.542 rs4630643 chr18:44508142 G/A cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.78 -0.39 4.89e-6 Personality dimensions; TGCT cis rs11190604 0.697 rs4559619 chr10:102199884 C/T cg16342193 chr10:102329863 NA 0.4 5.05 0.41 1.56e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs514406 0.525 rs269291 chr1:53189297 C/T cg01802117 chr1:53393560 SCP2 -0.39 -4.44 -0.37 1.94e-5 Monocyte count; TGCT cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg23283495 chr1:209979779 IRF6 -0.64 -5.55 -0.45 1.67e-7 Cleft lip with or without cleft palate; TGCT cis rs7917772 0.604 rs11191358 chr10:104399250 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.26 -0.43 6.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6558530 0.692 rs6981804 chr8:1700284 C/A cg09410841 chr8:1729607 CLN8 0.72 6.55 0.51 1.35e-9 Systolic blood pressure; TGCT cis rs9467773 0.838 rs3734540 chr6:26463321 A/C cg05738196 chr6:26577821 NA 0.68 7.66 0.57 4.58e-12 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg03517284 chr6:25882590 NA 0.52 4.73 0.39 6.01e-6 Intelligence (multi-trait analysis); TGCT trans rs10504390 0.656 rs74675840 chr8:66485845 G/A cg18118147 chr19:51128640 SYT3 -0.77 -6.81 -0.52 3.71e-10 IgG glycosylation; TGCT cis rs10197940 0.510 rs7557092 chr2:152423459 T/A cg06191203 chr2:152266755 RIF1 -0.69 -6.36 -0.5 3.52e-9 Lung cancer; TGCT trans rs4332037 0.624 rs58169303 chr7:1883274 T/C cg25206134 chr2:45395956 NA 0.92 7.78 0.57 2.44e-12 Bipolar disorder; TGCT cis rs9303542 0.559 rs2326012 chr17:46618581 C/T cg25032089 chr17:46643351 HOXB3 0.56 5.34 0.43 4.33e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs72781680 0.898 rs6545127 chr2:24060670 C/T cg08917208 chr2:24149416 ATAD2B 0.76 4.83 0.4 3.97e-6 Lymphocyte counts; TGCT cis rs509477 1.000 rs509477 chr18:32559295 C/G cg23791764 chr18:32556832 MAPRE2 0.59 4.83 0.4 3.9e-6 Cerebrospinal fluid AB1-42 levels; TGCT cis rs4820539 0.966 rs2267001 chr22:23456696 T/C cg14186256 chr22:23484241 RTDR1 1.0 12.28 0.74 3.58e-23 Bone mineral density; TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg01171360 chr6:293285 DUSP22 -0.78 -7.98 -0.58 8.31e-13 Menopause (age at onset); TGCT cis rs10779751 0.770 rs6701524 chr1:11198502 A/G cg08854313 chr1:11322531 MTOR -0.82 -6.66 -0.51 7.99e-10 Body mass index; TGCT cis rs2816062 0.965 rs2816061 chr1:18903819 A/G cg18795169 chr1:18902165 NA 0.57 12.57 0.75 7.15e-24 Urate levels in lean individuals; TGCT cis rs1056107 0.931 rs10759538 chr9:114996327 A/C cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs587847 0.597 rs17542178 chr15:37711776 G/T cg00216138 chr15:37171175 LOC145845 0.31 4.71 0.39 6.53e-6 Intraocular pressure; TGCT cis rs2228479 0.541 rs9922515 chr16:89954138 G/C cg06558623 chr16:89946397 TCF25 0.39 4.85 0.4 3.56e-6 Skin colour saturation; TGCT cis rs36051895 0.632 rs10974982 chr9:5149382 G/C cg02405213 chr9:5042618 JAK2 -0.75 -9.81 -0.66 3.74e-17 Pediatric autoimmune diseases; TGCT cis rs7666738 0.618 rs10856932 chr4:98819992 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.45 0.56 1.42e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1729951 0.575 rs1654923 chr3:136692620 A/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT trans rs1814175 0.817 rs2866863 chr11:49953242 C/T cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs748404 0.660 rs518288 chr15:43763999 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.77 0.39 5.05e-6 Lung cancer; TGCT cis rs6489882 0.548 rs15895 chr12:113448288 A/G cg04001726 chr12:112547043 NAA25 -0.44 -4.45 -0.37 1.91e-5 Chronic lymphocytic leukemia; TGCT cis rs12477438 0.520 rs6542869 chr2:99783403 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs28735056 0.935 rs72980082 chr18:77630170 G/T cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs3753275 0.568 rs7533113 chr1:8813243 C/T cg17029193 chr1:8510607 RERE -0.29 -4.48 -0.37 1.66e-5 Educational attainment; TGCT cis rs7666738 0.830 rs1534319 chr4:98964804 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6690583 0.943 rs1837329 chr1:85469614 G/A cg22153463 chr1:85462885 MCOLN2 -0.65 -4.47 -0.37 1.71e-5 Serum sulfate level; TGCT cis rs796364 0.951 rs281769 chr2:200809709 T/C cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs1865760 0.963 rs9356991 chr6:25901758 C/A cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT trans rs561341 0.663 rs72821936 chr17:30224068 C/G cg20587970 chr11:113659929 NA -0.58 -8.79 -0.62 1.04e-14 Hip circumference adjusted for BMI; TGCT trans rs62103177 0.525 rs4283293 chr18:77759582 A/G cg05926928 chr17:57297772 GDPD1 -0.76 -6.89 -0.53 2.48e-10 Opioid sensitivity; TGCT cis rs7169223 0.653 rs2904228 chr15:79086099 G/A cg03762349 chr15:79060523 ADAMTS7 0.25 4.92 0.4 2.68e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs877282 0.898 rs12359731 chr10:759497 A/G cg17470449 chr10:769945 NA 0.31 4.87 0.4 3.28e-6 Uric acid levels; TGCT cis rs7582180 0.629 rs12989897 chr2:100940998 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs4975709 0.589 rs1684967 chr5:1863055 G/C cg07747251 chr5:1868357 NA 0.36 5.12 0.42 1.12e-6 Cardiovascular disease risk factors; TGCT cis rs941873 0.900 rs7092536 chr10:81131332 A/C cg09469691 chr10:81107165 PPIF 0.56 5.42 0.44 3.05e-7 Height; TGCT cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg18252515 chr7:66147081 NA -1.27 -7.73 -0.57 3.17e-12 Diabetic kidney disease; TGCT cis rs12220898 0.568 rs4838376 chr10:50482048 T/C cg25968469 chr10:49687287 ARHGAP22 0.25 4.47 0.37 1.78e-5 Inflammatory biomarkers; TGCT cis rs6840360 0.615 rs58977077 chr4:152470239 T/G cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs13256369 0.774 rs13260303 chr8:8587342 A/C cg17143192 chr8:8559678 CLDN23 0.57 4.87 0.4 3.39e-6 Obesity-related traits; TGCT cis rs7618915 1.000 rs7618915 chr3:52279594 G/A cg10802521 chr3:52805072 NEK4 -0.5 -5.3 -0.43 5.1e-7 Bipolar disorder; TGCT cis rs11112613 0.762 rs73184077 chr12:105949999 G/A cg03607813 chr12:105948248 NA 0.52 6.0 0.47 2.03e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs1997103 1.000 rs10263552 chr7:55404747 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs58950470 0.521 rs7950197 chr11:65446126 T/C cg17480646 chr11:65405466 SIPA1 -0.41 -5.12 -0.42 1.14e-6 Schizophrenia; TGCT cis rs60843830 1.000 rs56321614 chr2:268191 G/T cg25945732 chr2:264204 ACP1;SH3YL1 0.72 7.27 0.55 3.56e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs78487399 0.808 rs79955955 chr2:43686985 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.06 -0.41 1.48e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg26818010 chr10:134567672 INPP5A -0.39 -5.36 -0.43 3.97e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2153535 0.505 rs1737583 chr6:8536812 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs6570726 0.577 rs399502 chr6:145805874 A/G cg05347473 chr6:146136440 FBXO30 0.62 5.75 0.46 6.64e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6728642 1.000 rs7593754 chr2:97607544 C/T cg26665480 chr2:98280029 ACTR1B -0.9 -5.45 -0.44 2.65e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs2178146 0.535 rs17266666 chr16:86448832 T/G cg11165158 chr16:86613094 FOXL1 0.35 4.67 0.39 7.79e-6 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT cis rs2243480 1.000 rs73150014 chr7:65450919 A/C cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs7226408 0.857 rs2162389 chr18:34437033 C/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7729723 0.556 rs13167336 chr5:137816101 G/C cg19169342 chr5:137827400 NA 0.32 4.67 0.39 7.63e-6 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs1008375 0.863 rs2058336 chr4:17608299 T/C cg16339924 chr4:17578868 LAP3 0.64 5.22 0.42 7.4e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs11722228 1.000 rs6823877 chr4:9921931 T/C cg26043149 chr18:55253948 FECH -0.74 -7.51 -0.56 9.93e-12 Gout;Urate levels;Serum uric acid levels; TGCT cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg07507251 chr3:52567010 NT5DC2 0.52 6.94 0.53 1.98e-10 Bipolar disorder; TGCT cis rs12908161 0.959 rs17534709 chr15:85314397 G/C cg11189052 chr15:85197271 WDR73 0.7 5.66 0.45 9.77e-8 Schizophrenia; TGCT cis rs17401966 0.838 rs4333852 chr1:10387704 A/T cg19773385 chr1:10388646 KIF1B 0.24 5.52 0.44 1.92e-7 Hepatocellular carcinoma; TGCT cis rs4862307 0.836 rs4862304 chr4:184996607 C/T cg06737308 chr4:185021514 ENPP6 0.32 4.58 0.38 1.1e-5 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs308403 0.509 rs309357 chr4:123653576 G/T cg10495464 chr4:123653540 BBS12;LOC729338 0.81 11.07 0.71 3.09e-20 Blood protein levels; TGCT cis rs7698623 0.850 rs4693895 chr4:88797839 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs9916302 0.610 rs11078902 chr17:37631883 C/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.79 -0.39 4.73e-6 Glomerular filtration rate (creatinine); TGCT trans rs561341 1.000 rs554078 chr17:30330109 A/C cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs6671200 1.000 rs34396223 chr1:95697828 C/T cg03123541 chr1:95699097 RWDD3 0.91 6.4 0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs73001065 0.786 rs72999033 chr19:19366632 C/T cg03709012 chr19:19516395 GATAD2A 1.25 5.53 0.44 1.82e-7 LDL cholesterol; TGCT cis rs9674544 0.740 rs11870560 chr17:47114033 T/C cg07075026 chr17:47091521 IGF2BP1 -0.45 -4.64 -0.38 8.84e-6 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs7100689 0.577 rs2185427 chr10:82056667 G/T cg01528321 chr10:82214614 TSPAN14 -0.68 -6.63 -0.51 9.17e-10 Post bronchodilator FEV1; TGCT cis rs138880 0.542 rs9616215 chr22:50318834 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.18 -5.98 -0.47 2.2e-8 Schizophrenia; TGCT cis rs7666738 0.830 rs28785514 chr4:98959135 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2594989 0.733 rs2616539 chr3:11580371 C/A cg00170343 chr3:11313890 ATG7 0.66 5.15 0.42 9.89e-7 Circulating chemerin levels; TGCT cis rs3008870 1.000 rs12039172 chr1:67447450 A/G cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs3793917 0.901 rs36212733 chr10:124215211 T/C cg09507567 chr10:124027408 NA 0.4 4.85 0.4 3.6e-6 Age-related macular degeneration; TGCT trans rs7726839 0.794 rs10053310 chr5:595661 C/G cg11887960 chr12:57824829 NA 0.95 7.37 0.55 2.12e-11 Obesity-related traits; TGCT cis rs7267979 0.789 rs6083810 chr20:25329759 T/A cg03522245 chr20:25566470 NINL -0.52 -5.23 -0.43 6.85e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6840360 0.642 rs7677131 chr4:152353015 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs7178572 1.000 rs12904938 chr15:77721225 A/G cg15453836 chr15:77711506 NA -0.39 -4.49 -0.37 1.62e-5 Type 2 diabetes; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg07167872 chr1:205819463 PM20D1 0.67 9.75 0.66 5.09e-17 Menarche (age at onset); TGCT cis rs4654899 0.680 rs10799670 chr1:21179445 T/C cg01072550 chr1:21505969 NA 0.54 8.72 0.62 1.54e-14 Superior frontal gyrus grey matter volume; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg07157834 chr1:205819609 PM20D1 0.52 9.21 0.64 1.02e-15 Menarche (age at onset); TGCT cis rs2204008 0.744 rs8189486 chr12:38244968 C/T cg13010199 chr12:38710504 ALG10B 0.64 5.01 0.41 1.85e-6 Bladder cancer; TGCT cis rs3125734 0.633 rs4979754 chr10:64048959 G/A cg09941381 chr10:64027924 RTKN2 -0.33 -4.94 -0.41 2.51e-6 Rheumatoid arthritis; TGCT cis rs7786808 0.741 rs35059736 chr7:158224692 C/T cg01191920 chr7:158217561 PTPRN2 -0.39 -5.89 -0.47 3.32e-8 Obesity-related traits; TGCT cis rs790110 1.000 rs60226894 chr3:122384152 C/T cg07366462 chr3:123162899 ADCY5 0.42 4.71 0.39 6.54e-6 Acoustic startle blink response; TGCT cis rs765787 0.530 rs55771002 chr15:45541566 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs4523957 0.620 rs9894215 chr17:2070698 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.46 -0.37 1.8e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10206020 0.921 rs4072986 chr2:1547734 C/G cg01028140 chr2:1542097 TPO -0.32 -4.65 -0.39 8.2e-6 IgG glycosylation; TGCT cis rs9916302 0.904 rs10491128 chr17:37551988 G/A cg07936489 chr17:37558343 FBXL20 0.62 4.78 0.39 4.9e-6 Glomerular filtration rate (creatinine); TGCT cis rs7647973 0.626 rs4855849 chr3:49653378 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs7681440 0.626 rs6812593 chr4:90817991 C/T cg10208370 chr4:90758469 SNCA -0.57 -5.41 -0.44 3.05e-7 Dementia with Lewy bodies; TGCT cis rs28595532 0.841 rs56388366 chr4:119769242 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs6424115 0.830 rs6663474 chr1:24199642 G/A cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs4727027 0.933 rs4725800 chr7:148862516 C/G cg23583168 chr7:148888333 NA -0.76 -10.09 -0.67 7.46e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6598955 0.543 rs57564009 chr1:26557618 A/T cg04990556 chr1:26633338 UBXN11 0.81 7.43 0.55 1.56e-11 Obesity-related traits; TGCT cis rs13191362 0.935 rs66507030 chr6:162953825 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.67 5.16 0.42 9.64e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10479542 0.806 rs4700835 chr5:178976313 A/G cg09060608 chr5:178986726 RUFY1 0.47 5.25 0.43 6.34e-7 Lung cancer; TGCT cis rs826838 0.868 rs864324 chr12:39122853 A/G cg13010199 chr12:38710504 ALG10B 0.56 4.51 0.38 1.51e-5 Heart rate; TGCT cis rs8033133 0.957 rs7162559 chr15:25352341 C/T cg14481604 chr15:25334117 SNORD116-22 0.3 6.27 0.49 5.57e-9 Blood osmolality (transformed sodium); TGCT cis rs12142240 0.698 rs56130131 chr1:46861306 A/C cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs57590327 0.555 rs2053805 chr3:81738414 T/C cg07356753 chr3:81810745 GBE1 -0.78 -7.36 -0.55 2.18e-11 Extraversion; TGCT cis rs6669919 1.000 rs6669919 chr1:211674383 T/C cg26515805 chr1:211431828 RCOR3 -0.4 -4.72 -0.39 6.33e-6 Intelligence (multi-trait analysis); TGCT cis rs7727544 0.716 rs4594848 chr5:131586598 C/A cg24060327 chr5:131705240 SLC22A5 -0.56 -5.45 -0.44 2.58e-7 Blood metabolite levels; TGCT cis rs9814567 1.000 rs7648990 chr3:134244390 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs63406760 1 rs63406760 chr12:123742692 TG/T cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Allergic disease (asthma, hay fever or eczema); TGCT cis rs11690462 0.895 rs11686204 chr2:26600226 G/A cg04726446 chr2:26624865 C2orf39 0.43 4.66 0.39 8.15e-6 Coronary artery disease; TGCT cis rs5750830 0.649 rs5750814 chr22:39797987 T/C cg05872129 chr22:39784769 NA -1.01 -11.68 -0.72 1.05e-21 Intelligence (multi-trait analysis); TGCT cis rs804280 1.000 rs804280 chr8:11612698 G/T cg02840367 chr8:11660030 FDFT1 -0.59 -4.67 -0.39 7.57e-6 Myopia (pathological); TGCT cis rs11122272 0.735 rs2808602 chr1:231537303 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT cis rs12530845 1.000 rs12540688 chr7:135329690 T/C cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs806215 0.951 rs327516 chr7:127255795 C/G cg25922125 chr7:127225783 GCC1 0.6 6.26 0.49 5.75e-9 Type 2 diabetes; TGCT cis rs4851254 0.660 rs58683655 chr2:100686519 G/C cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg03760483 chr17:6899297 ALOX12 0.45 5.36 0.43 3.87e-7 Tonsillectomy; TGCT cis rs9325144 0.534 rs4882283 chr12:38710249 C/T cg26384229 chr12:38710491 ALG10B 0.7 6.61 0.51 1.02e-9 Morning vs. evening chronotype; TGCT cis rs6770219 0.516 rs56228685 chr3:186140644 C/T cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.46 0.37 1.81e-5 Cerebrospinal T-tau levels; TGCT cis rs9926296 0.632 rs7206546 chr16:89799079 C/T cg26513180 chr16:89883248 FANCA -0.68 -6.62 -0.51 9.49e-10 Vitiligo; TGCT cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs2153535 0.580 rs6914276 chr6:8450435 A/T cg23788917 chr6:8435910 SLC35B3 -0.61 -5.61 -0.45 1.23e-7 Motion sickness; TGCT cis rs11098499 0.505 rs75122014 chr4:120362426 G/C cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7666738 0.546 rs28444809 chr4:98916934 C/T cg17366294 chr4:99064904 C4orf37 0.65 5.98 0.47 2.24e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9393777 0.513 rs13215020 chr6:26656073 G/A cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs7647973 1.000 rs7644148 chr3:49545241 G/A cg05785598 chr3:49045655 WDR6 -0.38 -4.5 -0.37 1.57e-5 Menarche (age at onset); TGCT cis rs7772486 0.875 rs12194437 chr6:146411440 A/G cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs8068544 0.748 rs75881902 chr17:40156612 C/A cg13092355 chr17:39992602 KLHL10;NT5C3L -0.95 -4.55 -0.38 1.24e-5 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.54 -0.51 1.42e-9 Alzheimer's disease; TGCT trans rs4650994 1.000 rs10913568 chr1:178513411 C/T cg05059571 chr16:84539110 KIAA1609 -0.42 -7.74 -0.57 3.02e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2832191 0.740 rs2832168 chr21:30463695 G/A cg08807101 chr21:30365312 RNF160 0.66 6.18 0.49 8.49e-9 Dental caries; TGCT cis rs4689388 0.750 rs10001190 chr4:6284633 C/T cg00701064 chr4:6280414 WFS1 -0.39 -5.01 -0.41 1.79e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9303401 0.659 rs34351230 chr17:56782555 C/A cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs6933660 0.646 rs9383899 chr6:151781022 G/C cg14262678 chr6:151773367 RMND1;C6orf211 0.49 4.68 0.39 7.39e-6 Menarche (age at onset); TGCT cis rs2594989 0.943 rs2244617 chr3:11503097 T/C cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.58e-5 Circulating chemerin levels; TGCT cis rs2227564 0.620 rs11000785 chr10:75575963 T/C cg19442545 chr10:75533431 FUT11 -0.31 -4.48 -0.37 1.65e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs10503709 0.581 rs17580809 chr8:21409341 A/G cg21031128 chr8:21771278 DOK2 -0.27 -4.54 -0.38 1.29e-5 Blood protein levels; TGCT cis rs11779988 0.500 rs208023 chr8:17878882 G/A cg08627089 chr8:17753878 FGL1 -0.28 -4.5 -0.37 1.55e-5 Breast cancer; TGCT cis rs79349575 0.687 rs12602179 chr17:47010034 G/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs6598955 0.627 rs12143920 chr1:26575834 A/G cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs1008375 0.966 rs3733581 chr4:17695206 C/G cg10189774 chr4:17578691 LAP3 -0.55 -4.56 -0.38 1.19e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs736408 1.000 rs736408 chr3:52835354 C/T cg10802521 chr3:52805072 NEK4 -0.65 -7.19 -0.54 5.37e-11 Bipolar disorder; TGCT cis rs1008375 0.966 rs3775923 chr4:17585625 T/C cg16339924 chr4:17578868 LAP3 0.83 7.21 0.54 4.92e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs6032067 0.516 rs761367 chr20:43913317 C/T cg16667508 chr20:43936853 MATN4;RBPJL -0.37 -5.93 -0.47 2.79e-8 Blood protein levels; TGCT cis rs17376456 1.000 rs59472588 chr5:93511981 A/G cg21475434 chr5:93447410 FAM172A 0.62 4.55 0.38 1.28e-5 Diabetic retinopathy; TGCT cis rs8180040 0.966 rs2101247 chr3:47494303 G/A cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs3780378 0.682 rs7861763 chr9:5273194 C/T cg02405213 chr9:5042618 JAK2 -0.54 -6.85 -0.52 3.01e-10 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs981844 0.890 rs62325115 chr4:154694847 A/G cg14289246 chr4:154710475 SFRP2 1.05 9.32 0.64 5.44e-16 Response to statins (LDL cholesterol change); TGCT cis rs12681287 0.752 rs12681438 chr8:87293089 G/A cg27223183 chr8:87520930 FAM82B -0.82 -5.86 -0.47 3.98e-8 Caudate activity during reward; TGCT cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg10802521 chr3:52805072 NEK4 -0.76 -9.36 -0.64 4.51e-16 Intelligence (multi-trait analysis); TGCT cis rs4722166 0.630 rs7781534 chr7:22778592 A/C cg26061582 chr7:22766209 IL6 0.57 7.36 0.55 2.27e-11 Lung cancer; TGCT cis rs1406084 0.636 rs10167490 chr2:154718155 T/C cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9372498 0.536 rs62663261 chr6:118900553 T/C cg07617317 chr6:118971624 C6orf204 0.49 5.19 0.42 8.37e-7 Diastolic blood pressure; TGCT cis rs9611565 0.592 rs6519270 chr22:42078666 A/G cg03806693 chr22:41940476 POLR3H 1.0 10.29 0.68 2.52e-18 Vitiligo; TGCT cis rs910316 0.737 rs175049 chr14:75481368 C/T cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.38e-7 Height; TGCT cis rs9393777 0.513 rs3999471 chr6:26650306 T/C cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs11711311 1.000 rs34475696 chr3:113458293 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.64 -0.38 8.55e-6 Bipolar disorder; TGCT cis rs5769765 0.908 rs9616370 chr22:50306316 A/G cg26441486 chr22:50317300 CRELD2 -0.28 -4.45 -0.37 1.92e-5 Schizophrenia; TGCT cis rs1129187 0.702 rs2395943 chr6:42940673 A/G cg10862848 chr6:42927986 GNMT -0.37 -4.47 -0.37 1.75e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9522267 0.535 rs9522298 chr13:112234457 C/A cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs1670533 0.932 rs13108207 chr4:1054218 C/T cg27284194 chr4:1044797 NA 0.67 5.98 0.47 2.21e-8 Recombination rate (females); TGCT trans rs3780486 0.505 rs10813959 chr9:33166234 C/T cg04842962 chr6:43655489 MRPS18A -0.81 -8.78 -0.62 1.1e-14 IgG glycosylation; TGCT cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs10751667 0.643 rs10902237 chr11:944801 C/A cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs597539 0.652 rs668576 chr11:68668208 A/G cg06028808 chr11:68637592 NA 0.52 6.84 0.52 3.18e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9916302 0.904 rs4357971 chr17:37717280 C/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs6543140 0.964 rs2080288 chr2:103022166 G/A cg09003973 chr2:102972529 NA 0.56 4.7 0.39 6.84e-6 Blood protein levels; TGCT cis rs4253772 0.591 rs6008384 chr22:46655948 T/C cg09491104 chr22:46646882 C22orf40 -0.65 -6.6 -0.51 1.05e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg10802521 chr3:52805072 NEK4 -0.79 -10.32 -0.68 2.06e-18 Bipolar disorder; TGCT cis rs854765 0.583 rs2350977 chr17:17802779 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.24e-12 Total body bone mineral density; TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs6671200 0.920 rs7555236 chr1:95631314 G/A cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs9611519 1.000 rs2057070 chr22:41564287 T/C cg13695892 chr22:41940480 POLR3H -0.5 -4.51 -0.38 1.5e-5 Neuroticism; TGCT cis rs4819052 0.684 rs914216 chr21:46698298 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 7.02 0.53 1.27e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs79349575 0.783 rs318096 chr17:46975370 G/A cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.04e-6 Type 2 diabetes; TGCT cis rs9926296 0.605 rs886951 chr16:89836865 A/G cg21285383 chr16:89894308 SPIRE2 0.42 6.61 0.51 1.01e-9 Vitiligo; TGCT cis rs2456568 0.803 rs10831141 chr11:93640728 C/T cg16099599 chr11:93583650 C11orf90 -0.4 -4.87 -0.4 3.38e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3008870 1.000 rs2755240 chr1:67477339 T/G cg03991309 chr1:68237761 GNG12 0.26 4.46 0.37 1.83e-5 Lymphocyte percentage of white cells; TGCT cis rs829418 0.901 rs947334 chr1:21938897 A/G cg04260293 chr1:22924330 EPHA8 0.35 4.45 0.37 1.88e-5 Neurocognitive impairment in HIV-1 infection (continuous); TGCT cis rs7179456 0.547 rs6494036 chr15:59015961 A/T cg05156742 chr15:59063176 FAM63B 0.51 5.05 0.41 1.52e-6 Asperger disorder; TGCT cis rs425277 0.958 rs262688 chr1:2113565 T/G cg03732007 chr1:2071316 PRKCZ 0.25 5.27 0.43 5.86e-7 Height; TGCT cis rs7226408 0.857 rs59634585 chr18:34437032 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9486719 0.857 rs1157316 chr6:96869710 G/A cg06623918 chr6:96969491 KIAA0776 1.03 10.94 0.7 6.47e-20 Migraine;Coronary artery disease; TGCT cis rs1532993 0.518 rs28874284 chr4:98616319 T/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg18402987 chr7:1209562 NA 0.74 6.21 0.49 7.23e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10782582 0.609 rs1796815 chr1:76396793 T/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.54 4.64 0.38 8.58e-6 Daytime sleep phenotypes; TGCT cis rs6860806 0.507 rs156322 chr5:131653925 C/T cg24060327 chr5:131705240 SLC22A5 -0.77 -8.17 -0.59 3.05e-13 Breast cancer; TGCT cis rs8180040 0.966 rs34634681 chr3:47579102 G/A cg27129171 chr3:47204927 SETD2 -0.64 -7.34 -0.55 2.41e-11 Colorectal cancer; TGCT cis rs1005277 0.579 rs1780139 chr10:38503018 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6500602 0.701 rs4785968 chr16:4535307 T/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.45 0.5 2.24e-9 Schizophrenia; TGCT cis rs16957091 0.647 rs28494835 chr15:43281391 C/T cg17935677 chr15:44119062 WDR76 0.53 4.74 0.39 5.73e-6 MGMT methylation in smokers; TGCT cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 -0.3 -5.32 -0.43 4.76e-7 Schizophrenia; TGCT cis rs7246657 0.943 rs4417644 chr19:37852472 A/G cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs2730245 0.645 rs4909282 chr7:158699797 T/C cg11984989 chr7:158649758 WDR60 1.07 10.3 0.68 2.36e-18 Height; TGCT trans rs1496653 0.602 rs13076412 chr3:23554950 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs17711722 0.727 rs2658585 chr7:65461941 A/T cg18876405 chr7:65276391 NA 0.38 5.89 0.47 3.32e-8 Calcium levels; TGCT cis rs644799 1.000 rs593665 chr11:95574302 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 9.9 0.66 2.27e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10892173 0.678 rs4537790 chr11:117661356 A/G cg21640587 chr11:117668038 DSCAML1 0.47 4.97 0.41 2.18e-6 Myopia; TGCT cis rs1670533 0.769 rs6814833 chr4:1057679 A/C cg20887711 chr4:1340912 KIAA1530 0.68 5.25 0.43 6.4e-7 Recombination rate (females); TGCT cis rs11809207 1.000 rs55695238 chr1:26521931 C/G cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs2760061 0.626 rs672907 chr1:228120345 G/A cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs9443645 0.901 rs1960542 chr6:79566643 C/T cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.66e-6 Intelligence (multi-trait analysis); TGCT cis rs7954584 0.520 rs1169094 chr12:122465535 A/G cg13699009 chr12:122356056 WDR66 -0.22 -4.59 -0.38 1.05e-5 Mean corpuscular volume; TGCT cis rs9467711 0.516 rs501220 chr6:25873025 C/A cg12310025 chr6:25882481 NA -0.75 -5.0 -0.41 1.88e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs10782582 0.532 rs78106188 chr1:76137836 A/G cg10523679 chr1:76189770 ACADM -0.69 -7.16 -0.54 6.4e-11 Daytime sleep phenotypes; TGCT cis rs6495122 0.699 rs4886410 chr15:75065644 G/C cg13906792 chr15:75199810 C15orf17 -0.22 -4.5 -0.37 1.55e-5 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs4499344 0.696 rs2868154 chr19:33099305 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.54 0.61 4.15e-14 Mean platelet volume; TGCT cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg03264133 chr6:25882463 NA -0.66 -6.11 -0.48 1.19e-8 Intelligence (multi-trait analysis); TGCT cis rs11955175 1.000 rs112239156 chr5:40649478 A/C cg17351974 chr5:40835760 RPL37 0.76 4.8 0.4 4.43e-6 Bipolar disorder and schizophrenia; TGCT trans rs4332037 0.950 rs62442895 chr7:1936938 G/A cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs798766 1.000 rs1665362 chr4:1726367 T/A cg05874882 chr4:1763078 NA -0.36 -4.87 -0.4 3.27e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs12142240 0.698 rs7548675 chr1:46809321 C/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs10791097 0.720 rs4936121 chr11:130733878 A/G cg14779329 chr11:130786720 SNX19 0.31 5.09 0.42 1.31e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2153535 0.580 rs6938071 chr6:8464845 A/T cg07606381 chr6:8435919 SLC35B3 0.55 5.16 0.42 9.35e-7 Motion sickness; TGCT cis rs62064224 0.589 rs2041306 chr17:30665675 T/C cg18200150 chr17:30822561 MYO1D 0.39 4.58 0.38 1.09e-5 Schizophrenia; TGCT cis rs7635838 0.596 rs4684765 chr3:11261085 G/C cg00170343 chr3:11313890 ATG7 0.65 6.15 0.48 9.62e-9 HDL cholesterol; TGCT cis rs709400 1.000 rs861531 chr14:104172807 C/A cg26031613 chr14:104095156 KLC1 1.13 16.72 0.83 1.42e-33 Body mass index; TGCT cis rs1008375 0.932 rs4698628 chr4:17608620 A/G cg16339924 chr4:17578868 LAP3 0.64 5.22 0.42 7.4e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs174601 0.864 rs174545 chr11:61569306 C/G cg19610905 chr11:61596333 FADS2 -1.09 -11.84 -0.73 4.21e-22 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg26531700 chr6:26746687 NA -0.68 -6.72 -0.52 5.79e-10 Schizophrenia; TGCT cis rs7267979 0.932 rs6138588 chr20:25487523 C/T cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs910316 0.967 rs2268619 chr14:75640354 C/G cg11812906 chr14:75593930 NEK9 -0.73 -6.79 -0.52 4.1e-10 Height; TGCT cis rs1729951 0.575 rs361241 chr3:136699561 C/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs7677751 0.806 rs7673853 chr4:55096606 T/C cg17187183 chr4:55093834 PDGFRA 0.53 6.92 0.53 2.19e-10 Corneal astigmatism; TGCT cis rs4512344 0.509 rs2409784 chr8:11396856 G/T cg21775007 chr8:11205619 TDH -0.46 -4.49 -0.37 1.64e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2836974 0.897 rs2026265 chr21:40595517 G/A cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.3e-9 Cognitive function; TGCT cis rs9916302 0.808 rs12947281 chr17:37652210 G/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs10992471 0.603 rs12336415 chr9:95195458 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.94 -0.47 2.62e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7216064 1.000 rs62084249 chr17:65874998 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7552404 0.691 rs5745449 chr1:76344711 A/T cg10523679 chr1:76189770 ACADM -0.83 -7.8 -0.57 2.24e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1997103 1.000 rs2331065 chr7:55408392 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1215050 0.740 rs1084777 chr4:99017542 C/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.99 -0.41 1.95e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg18252515 chr7:66147081 NA -1.2 -7.16 -0.54 6.16e-11 Diabetic kidney disease; TGCT cis rs208520 0.661 rs851466 chr6:66840476 A/G cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.41 7.12 0.54 7.77e-11 Schizophrenia; TGCT cis rs9916302 0.861 rs7503514 chr17:37669884 G/C cg15445000 chr17:37608096 MED1 0.32 4.66 0.39 8.18e-6 Glomerular filtration rate (creatinine); TGCT cis rs2439831 0.850 rs28413881 chr15:44174099 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.16 0.48 9.29e-9 Lung cancer in ever smokers; TGCT cis rs60843830 0.661 rs6755432 chr2:106692 T/C cg25945732 chr2:264204 ACP1;SH3YL1 0.63 5.58 0.45 1.41e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1075232 0.826 rs12438813 chr15:31705913 C/T cg01030201 chr15:31746330 NA -1.01 -5.26 -0.43 6.07e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs6570726 0.905 rs430248 chr6:145874104 A/G cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1372520 0.748 rs1471484 chr4:90754313 C/T cg14346243 chr4:90757452 SNCA -0.65 -5.37 -0.43 3.8e-7 Neuroticism; TGCT cis rs3617 0.573 rs56383738 chr3:52908398 T/C cg10802521 chr3:52805072 NEK4 0.56 6.3 0.49 4.72e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg08736216 chr1:53307985 ZYG11A -0.24 -4.89 -0.4 3e-6 Monocyte count; TGCT cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.28 0.49 5.18e-9 Schizophrenia; TGCT cis rs904251 0.797 rs2776878 chr6:37487273 G/A cg25019722 chr6:37503610 NA -0.51 -7.03 -0.53 1.24e-10 Cognitive performance; TGCT cis rs6500602 0.592 rs4785966 chr16:4518754 C/T cg08645402 chr16:4508243 NA -0.22 -5.17 -0.42 9e-7 Schizophrenia; TGCT cis rs12579753 0.833 rs12579530 chr12:82163930 A/C cg07988820 chr12:82153109 PPFIA2 -0.67 -7.61 -0.56 5.92e-12 Resting heart rate; TGCT cis rs908922 0.676 rs526099 chr1:152497811 T/C cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.26e-9 Hair morphology; TGCT cis rs36051895 0.632 rs12337904 chr9:5144606 C/G cg02405213 chr9:5042618 JAK2 -0.72 -10.05 -0.67 9.59e-18 Pediatric autoimmune diseases; TGCT cis rs8062405 0.789 rs240704 chr16:28529949 T/C cg09754948 chr16:28834200 ATXN2L 0.56 4.46 0.37 1.78e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7394190 0.748 rs4114992 chr10:75566829 A/G cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs4466137 0.830 rs6886442 chr5:82973210 A/C cg16102102 chr5:83017553 HAPLN1 0.8 8.55 0.61 3.86e-14 Prostate cancer; TGCT cis rs986417 0.901 rs8020084 chr14:61001495 C/T cg27398547 chr14:60952738 C14orf39 1.52 9.5 0.65 2.04e-16 Gut microbiota (bacterial taxa); TGCT cis rs644799 0.965 rs10831430 chr11:95509638 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.82 0.7 1.31e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs7618501 1.000 rs3749240 chr3:49750188 T/A cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs72705102 chr5:659437 T/C cg09021430 chr5:549028 NA -0.45 -6.13 -0.48 1.08e-8 Obesity-related traits; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg01238044 chr22:24384105 GSTT1 0.49 4.64 0.38 8.71e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs9951602 0.512 rs1599636 chr18:76643916 G/A cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs6977955 0.877 rs9648346 chr7:28160113 C/G cg23620719 chr7:28220237 JAZF1 0.65 4.95 0.41 2.36e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1903068 0.785 rs10020668 chr4:55996903 C/T cg01777861 chr4:56023843 NA 0.53 6.17 0.48 8.85e-9 Endometriosis; TGCT cis rs9467711 0.516 rs1324087 chr6:25841408 A/G cg03517284 chr6:25882590 NA 0.73 4.85 0.4 3.62e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg06481639 chr22:41940642 POLR3H 0.67 5.82 0.46 4.74e-8 Vitiligo; TGCT cis rs597539 0.652 rs654071 chr11:68653432 A/C cg04772025 chr11:68637568 NA 0.6 6.67 0.51 7.4e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4499344 0.664 rs7258278 chr19:33099523 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg19729930 chr2:74357872 NA 0.51 6.1 0.48 1.24e-8 Gestational age at birth (maternal effect); TGCT cis rs7647973 0.731 rs13084037 chr3:49214066 G/A cg07636037 chr3:49044803 WDR6 0.65 4.84 0.4 3.75e-6 Menarche (age at onset); TGCT trans rs1814175 0.529 rs10839396 chr11:49852406 G/T cg03929089 chr4:120376271 NA 0.62 6.79 0.52 4.07e-10 Height; TGCT cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg03806693 chr22:41940476 POLR3H -1.09 -12.4 -0.74 1.86e-23 Vitiligo; TGCT cis rs7439150 0.954 rs4681 chr4:155490832 C/T cg22130008 chr4:155548532 NA -0.51 -6.18 -0.49 8.4e-9 Fibrinogen levels; TGCT cis rs4862750 0.914 rs1991256 chr4:187875330 A/G cg10295955 chr4:187884368 NA -0.97 -14.76 -0.8 4.41e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs950169 0.723 rs17589320 chr15:84919996 C/A cg11189052 chr15:85197271 WDR73 0.83 6.67 0.51 7.71e-10 Schizophrenia; TGCT cis rs2692947 0.696 rs2576437 chr2:96800417 T/C cg23100626 chr2:96804247 ASTL 0.41 5.06 0.41 1.46e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7819412 1.000 rs7819412 chr8:11045161 A/G cg21775007 chr8:11205619 TDH 0.51 4.88 0.4 3.2e-6 Triglycerides; TGCT cis rs9926296 0.586 rs1800359 chr16:89805261 A/G cg26513180 chr16:89883248 FANCA 0.71 6.93 0.53 2.07e-10 Vitiligo; TGCT cis rs7681440 0.904 rs6816305 chr4:90772902 C/G cg20003494 chr4:90757398 SNCA -0.59 -5.52 -0.44 1.9e-7 Dementia with Lewy bodies; TGCT cis rs11690935 0.885 rs6727017 chr2:172766847 T/A cg13550731 chr2:172543902 DYNC1I2 -0.92 -8.36 -0.6 1.11e-13 Schizophrenia; TGCT cis rs6570726 0.599 rs9403725 chr6:145897622 A/T cg05347473 chr6:146136440 FBXO30 -0.62 -5.73 -0.46 7.35e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2235642 0.750 rs763152 chr16:1658056 T/C cg00463982 chr16:1583984 IFT140;TMEM204 -0.27 -4.56 -0.38 1.22e-5 Coronary artery disease; TGCT cis rs6831352 0.918 rs29001209 chr4:100052340 C/A cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs13188771 0.690 rs164621 chr5:100873520 A/G cg18665594 chr5:101119420 NA 0.44 4.46 0.37 1.83e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7845219 0.544 rs4735332 chr8:95923660 C/T cg16049864 chr8:95962084 TP53INP1 -0.48 -5.25 -0.43 6.29e-7 Type 2 diabetes; TGCT cis rs10791097 0.547 rs12365680 chr11:130749059 C/T cg05962950 chr11:130786565 SNX19 0.93 12.26 0.74 3.95e-23 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9926296 0.712 rs447735 chr16:89734349 T/C cg01097406 chr16:89675127 NA 0.35 6.09 0.48 1.29e-8 Vitiligo; TGCT cis rs919433 0.679 rs61155920 chr2:198528881 C/T cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.7e-7 Developmental language disorder (linguistic errors); TGCT cis rs75059851 0.756 rs11223654 chr11:133841579 C/T cg14047540 chr11:133829660 NA -0.55 -5.45 -0.44 2.57e-7 Schizophrenia; TGCT cis rs6964587 1.000 rs61244255 chr7:91751662 C/T cg22709100 chr7:91322751 NA 0.29 4.69 0.39 6.98e-6 Breast cancer; TGCT cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg06481639 chr22:41940642 POLR3H 0.73 6.49 0.5 1.83e-9 Vitiligo; TGCT cis rs1045714 0.836 rs73033691 chr7:2636522 T/G cg17215154 chr7:2644645 IQCE 0.29 5.12 0.42 1.12e-6 Urate levels in lean individuals; TGCT cis rs6570726 0.967 rs439017 chr6:145806123 T/C cg23711669 chr6:146136114 FBXO30 0.64 6.08 0.48 1.37e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs61990749 0.597 rs2112136 chr14:78248952 T/C cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs7104764 0.957 rs3829998 chr11:230751 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.05 10.79 0.7 1.48e-19 Menarche (age at onset); TGCT cis rs2675609 0.647 rs2675595 chr10:63616669 A/C cg10604396 chr10:64577901 EGR2 0.47 4.45 0.37 1.91e-5 Serum total protein level; TGCT cis rs922182 0.556 rs10851734 chr15:64216247 C/T cg02919090 chr15:64263738 DAPK2 -0.37 -6.77 -0.52 4.69e-10 Blood protein levels; TGCT cis rs10927875 0.541 rs1763607 chr1:16337509 G/A cg22431228 chr1:16359049 CLCNKA -0.29 -5.97 -0.47 2.33e-8 Dilated cardiomyopathy; TGCT cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg12756686 chr19:29218302 NA 0.68 6.39 0.5 3.07e-9 Methadone dose in opioid dependence; TGCT cis rs1218582 0.772 rs1976559 chr1:154879788 A/T cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs12134245 0.776 rs13447526 chr1:91983174 A/G cg07090678 chr1:91966139 CDC7 -0.37 -5.05 -0.41 1.56e-6 Breast cancer; TGCT cis rs7804356 1.000 rs10267950 chr7:26826757 T/A cg03456212 chr7:26904342 SKAP2 -0.64 -4.88 -0.4 3.16e-6 Type 1 diabetes; TGCT cis rs7937682 0.889 rs542424 chr11:111477698 T/C cg09085632 chr11:111637200 PPP2R1B -1.04 -11.09 -0.71 2.89e-20 Primary sclerosing cholangitis; TGCT cis rs3820928 0.874 rs1917122 chr2:227835681 C/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs617219 0.671 rs13165414 chr5:78548873 C/T cg09550809 chr5:78407562 BHMT 0.37 5.24 0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6539288 0.589 rs1037013 chr12:107219308 A/G cg15890332 chr12:107067104 RFX4 0.23 4.7 0.39 6.84e-6 Total body bone mineral density; TGCT cis rs875971 0.543 rs801191 chr7:66032955 G/A cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs2204008 0.702 rs3849999 chr12:38483498 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Bladder cancer; TGCT cis rs11190604 1.000 rs10883505 chr10:102280772 C/T cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12142240 0.698 rs12385697 chr1:46818898 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7666738 0.830 rs17558151 chr4:99048699 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2180341 0.883 rs6904630 chr6:127696869 A/G cg27446573 chr6:127587934 RNF146 1.16 10.52 0.69 6.95e-19 Breast cancer; TGCT cis rs6977660 0.714 rs10228783 chr7:19789290 C/T cg07541023 chr7:19748670 TWISTNB 0.83 4.69 0.39 7.01e-6 Thyroid stimulating hormone; TGCT trans rs9467711 1.000 rs9467701 chr6:26312170 G/C cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs9796 0.621 rs58109657 chr15:41471750 A/G cg18705301 chr15:41695430 NDUFAF1 0.52 7.17 0.54 5.94e-11 Menopause (age at onset); TGCT cis rs9436747 0.803 rs1751490 chr1:66007430 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.5 4.86 0.4 3.51e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs801193 0.660 rs4610622 chr7:66224497 T/C cg18876405 chr7:65276391 NA 0.33 4.97 0.41 2.13e-6 Aortic root size; TGCT cis rs7819412 0.678 rs11991716 chr8:10948575 A/T cg27411982 chr8:10470053 RP1L1 -0.22 -4.58 -0.38 1.11e-5 Triglycerides; TGCT cis rs7949030 0.591 rs35880596 chr11:62369884 C/G cg22862634 chr11:62369728 EML3;MTA2 0.7 8.76 0.62 1.26e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12048904 0.619 rs12239082 chr1:101330077 G/T cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.67 -5.76 -0.46 6.18e-8 Multiple sclerosis; TGCT cis rs9291683 0.546 rs12504565 chr4:10045145 G/A cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Bone mineral density; TGCT cis rs4665809 1.000 rs4665820 chr2:26309150 T/C cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs9653442 0.628 rs12474386 chr2:100857017 G/A cg07810366 chr2:100720526 AFF3 -0.42 -6.52 -0.51 1.62e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs114314373 chr4:119639128 G/A cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.66e-7 Cannabis dependence symptom count; TGCT cis rs4819852 0.958 rs9606204 chr22:19976510 C/A cg07821417 chr22:19972146 ARVCF 0.19 4.79 0.4 4.7e-6 Pulse pressure; TGCT cis rs7107174 1.000 rs7104222 chr11:78007169 G/A cg12700464 chr11:78128424 GAB2 -0.68 -4.64 -0.38 8.71e-6 Testicular germ cell tumor; TGCT cis rs9467773 1.000 rs1321481 chr6:26538210 A/T cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs4595586 0.546 rs11169801 chr12:39241429 G/A cg26384229 chr12:38710491 ALG10B 0.65 5.29 0.43 5.43e-7 Morning vs. evening chronotype; TGCT cis rs7826238 0.535 rs2979179 chr8:8320029 C/T cg06636001 chr8:8085503 FLJ10661 0.79 7.37 0.55 2.1e-11 Systolic blood pressure; TGCT cis rs4595586 0.545 rs12815047 chr12:39380901 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs35146811 0.695 rs1727132 chr7:99812297 T/C cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs7786808 0.544 rs6971888 chr7:158193835 G/A cg01191920 chr7:158217561 PTPRN2 0.36 5.26 0.43 6.23e-7 Obesity-related traits; TGCT cis rs6671200 0.831 rs9659908 chr1:95656127 C/T cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs7267979 1.000 rs34645895 chr20:25368373 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs711245 0.670 rs7560321 chr2:36822318 C/G cg15105969 chr2:36825350 FEZ2 -0.61 -6.07 -0.48 1.43e-8 Height; TGCT cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg03303774 chr4:1407052 NA 0.29 4.67 0.39 7.71e-6 Obesity-related traits; TGCT cis rs35771425 0.536 rs6656860 chr1:211620805 A/G cg26515805 chr1:211431828 RCOR3 -0.44 -5.09 -0.42 1.27e-6 Educational attainment (years of education); TGCT cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg15659132 chr6:26577336 NA 0.87 10.72 0.69 2.19e-19 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs17221829 0.965 rs10830359 chr11:89455444 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.66 -0.39 7.9e-6 Anxiety in major depressive disorder; TGCT cis rs2847281 0.614 rs2847262 chr18:12775295 T/G cg23598886 chr18:12777645 NA 0.37 4.69 0.39 7.07e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -6.14 -0.48 1.04e-8 Type 2 diabetes; TGCT cis rs950169 1.000 rs79318564 chr15:84786150 G/A cg17173187 chr15:85201210 NMB 0.51 5.6 0.45 1.3e-7 Schizophrenia; TGCT cis rs2288278 0.601 rs12450225 chr17:46592413 A/G cg25032089 chr17:46643351 HOXB3 -0.42 -5.0 -0.41 1.87e-6 Hand grip strength; TGCT cis rs2439831 0.850 rs524417 chr15:43772374 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.98 7.72 0.57 3.37e-12 Lung cancer in ever smokers; TGCT cis rs5769707 0.642 rs4824070 chr22:50031521 T/C cg05373962 chr22:49881684 NA -0.31 -5.28 -0.43 5.72e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10465746 0.725 rs4907185 chr1:84336047 T/C cg10977910 chr1:84465055 TTLL7 0.68 6.7 0.52 6.46e-10 Obesity-related traits; TGCT cis rs4824093 0.610 rs3761496 chr22:50246466 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.48 4.93 0.41 2.53e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7635838 0.617 rs367745 chr3:11309274 T/C cg00170343 chr3:11313890 ATG7 0.63 6.19 0.49 7.96e-9 HDL cholesterol; TGCT cis rs36051895 0.555 rs6476953 chr9:5248742 C/T cg02405213 chr9:5042618 JAK2 -0.7 -8.98 -0.63 3.67e-15 Pediatric autoimmune diseases; TGCT cis rs7824557 0.583 rs4448232 chr8:11231354 G/T cg21775007 chr8:11205619 TDH 0.69 6.99 0.53 1.46e-10 Retinal vascular caliber; TGCT cis rs3858526 0.959 rs10838901 chr11:5959128 G/A cg13902645 chr11:5959945 NA -0.44 -4.72 -0.39 6.39e-6 DNA methylation (variation); TGCT cis rs2404602 0.716 rs7164060 chr15:76707694 T/C cg22467129 chr15:76604101 ETFA -0.59 -7.13 -0.54 7.33e-11 Blood metabolite levels; TGCT cis rs9467711 0.591 rs41266779 chr6:26021872 C/T cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg11644478 chr21:40555479 PSMG1 -0.63 -5.92 -0.47 2.95e-8 Cognitive function; TGCT cis rs11792861 0.890 rs57387569 chr9:111920392 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.49 0.37 1.63e-5 Menarche (age at onset); TGCT cis rs1475911 0.708 rs56185023 chr21:43521538 T/C cg24372256 chr21:43528868 UMODL1;C21orf128 -0.31 -5.88 -0.47 3.64e-8 IgG glycosylation; TGCT cis rs7914558 0.505 rs12260436 chr10:104741114 A/C cg04362960 chr10:104952993 NT5C2 0.64 5.33 0.43 4.48e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4919669 0.777 rs12415043 chr10:104467609 C/G cg05855489 chr10:104503620 C10orf26 -0.71 -4.5 -0.37 1.57e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs77106637 1.000 rs11605166 chr11:72669777 T/C cg03713592 chr11:72463424 ARAP1 0.79 5.13 0.42 1.09e-6 Type 2 diabetes; TGCT trans rs17685 0.784 rs1637043 chr7:75699099 G/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.59 0.61 3.07e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs265548 0.586 rs265542 chr19:17904388 T/G cg03316864 chr19:17906309 B3GNT3 0.43 5.0 0.41 1.88e-6 Tumor biomarkers; TGCT cis rs7909074 1.000 rs10900128 chr10:45393201 G/T cg04218760 chr10:45406644 TMEM72 -0.27 -5.55 -0.45 1.64e-7 Mean corpuscular volume; TGCT cis rs7666738 0.791 rs7684521 chr4:99071219 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.42 0.55 1.63e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs4803468 1.000 rs4803463 chr19:41911040 C/G cg09537434 chr19:41945824 ATP5SL -0.92 -10.69 -0.69 2.72e-19 Height; TGCT cis rs9430161 0.579 rs6696575 chr1:11037136 G/A cg27631724 chr1:11040367 C1orf127 0.54 6.28 0.49 5.3300000000000004e-09 Ewing sarcoma; TGCT cis rs1008375 0.800 rs28754811 chr4:17612312 C/T cg18681998 chr4:17616180 MED28 1.0 10.67 0.69 3.01e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2288278 0.619 rs10853100 chr17:46602432 T/C cg25032089 chr17:46643351 HOXB3 -0.42 -5.0 -0.41 1.89e-6 Hand grip strength; TGCT cis rs4803468 1.000 rs2569754 chr19:41936734 A/G cg09537434 chr19:41945824 ATP5SL -0.91 -10.05 -0.67 9.48e-18 Height; TGCT cis rs61861422 0.516 rs12412216 chr10:134393338 C/T cg22868943 chr10:134019008 DPYSL4 0.3 5.31 0.43 4.86e-7 Primary sclerosing cholangitis; TGCT cis rs3806843 0.576 rs246029 chr5:140333226 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs858239 0.899 rs28458177 chr7:23294872 G/A cg05602783 chr7:23145260 KLHL7 -0.63 -4.96 -0.41 2.31e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9653442 0.545 rs11123810 chr2:100759285 T/C cg22139774 chr2:100720529 AFF3 -0.36 -5.63 -0.45 1.16e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs7552404 0.960 rs61797339 chr1:76189946 G/T cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7772486 0.875 rs9322044 chr6:146369608 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.46 -0.37 1.83e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9787249 0.957 rs6670841 chr1:40220284 C/G cg19912559 chr1:40204330 PPIE 0.47 5.52 0.44 1.88e-7 Blood protein levels; TGCT cis rs7523273 0.565 rs2761420 chr1:207889368 G/T cg22525895 chr1:207977042 MIR29B2 -0.35 -5.67 -0.45 9.4e-8 Schizophrenia; TGCT cis rs28735056 0.904 rs35201860 chr18:77628719 T/C cg20368463 chr18:77673604 PQLC1 0.4 4.89 0.4 3.09e-6 Schizophrenia; TGCT cis rs4927850 1.000 rs7627706 chr3:195753353 A/C cg22891161 chr3:195456627 MUC20 -0.23 -5.38 -0.44 3.53e-7 Pancreatic cancer; TGCT cis rs9325144 0.624 rs7309400 chr12:39150369 G/C cg26384229 chr12:38710491 ALG10B -0.61 -5.69 -0.46 8.63e-8 Morning vs. evening chronotype; TGCT trans rs7618501 1.000 rs2271960 chr3:49878078 A/G cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs4478858 0.735 rs10914361 chr1:31817542 T/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs4906332 0.966 rs12588705 chr14:103865477 T/A cg26031613 chr14:104095156 KLC1 -0.51 -4.65 -0.39 8.49e-6 Coronary artery disease; TGCT cis rs72781680 0.898 rs111460347 chr2:24018833 G/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs2233152 0.656 rs10405633 chr19:41291703 G/A cg23743927 chr19:41304969 EGLN2 -0.7 -4.69 -0.39 7.06e-6 Kawasaki disease; TGCT cis rs2235642 0.691 rs2281235 chr16:1603535 T/C cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.42 -0.44 2.97e-7 Coronary artery disease; TGCT cis rs7824557 0.778 rs3808502 chr8:11179458 G/T cg21775007 chr8:11205619 TDH 0.55 5.11 0.42 1.2e-6 Retinal vascular caliber; TGCT cis rs10791097 0.694 rs4264159 chr11:130755784 G/T cg05962950 chr11:130786565 SNX19 0.9 11.06 0.7 3.32e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2303745 0.544 rs6512180 chr19:17399153 C/T cg04248312 chr19:17393744 ANKLE1 -0.33 -5.51 -0.44 1.96e-7 Systemic lupus erythematosus; TGCT cis rs7523273 0.526 rs2724394 chr1:208017072 T/A cg22525895 chr1:207977042 MIR29B2 -0.53 -8.98 -0.63 3.6e-15 Schizophrenia; TGCT cis rs3015497 0.616 rs4901044 chr14:51090295 A/G cg04730355 chr14:51134070 SAV1 -0.64 -6.04 -0.48 1.64e-8 Mean platelet volume; TGCT cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg10802521 chr3:52805072 NEK4 -0.79 -9.98 -0.67 1.39e-17 Bipolar disorder; TGCT cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.81 0.46 4.96e-8 Height; TGCT cis rs477895 0.713 rs7952318 chr11:63961242 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.33 0.49 4.14e-9 Mean platelet volume; TGCT cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg27588902 chr6:42928151 GNMT -0.56 -6.99 -0.53 1.48e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg11965913 chr1:205819406 PM20D1 0.48 6.26 0.49 5.7e-9 Menarche (age at onset); TGCT cis rs67072384 1.000 rs67072384 chr11:72450724 C/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs42648 0.596 rs194518 chr7:89853149 G/A cg25739043 chr7:89950458 NA -0.51 -4.85 -0.4 3.65e-6 Homocysteine levels; TGCT cis rs950027 0.549 rs12909409 chr15:45608582 T/G cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.44 -0.56 1.48e-11 Response to fenofibrate (adiponectin levels); TGCT cis rs6089829 0.925 rs3746748 chr20:61667526 C/T cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs9372253 1.000 rs9386894 chr6:110718853 A/G cg00083206 chr6:110721305 DDO -0.44 -6.68 -0.51 7.27e-10 Platelet distribution width; TGCT cis rs7772486 0.597 rs2246132 chr6:146182515 C/G cg23711669 chr6:146136114 FBXO30 0.74 6.88 0.53 2.65e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs11085466 1.000 rs73552468 chr19:21772097 G/A cg23026602 chr19:21646605 NA -0.55 -4.82 -0.4 4.2e-6 Colorectal or endometrial cancer; TGCT cis rs2075371 1.000 rs1421486 chr7:133985196 T/C cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs4499344 0.556 rs259220 chr19:33137629 T/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.26 0.6 1.84e-13 Mean platelet volume; TGCT cis rs10464366 0.746 rs11760807 chr7:39142377 G/A cg15212455 chr7:39170539 POU6F2 0.26 5.62 0.45 1.19e-7 IgG glycosylation; TGCT cis rs950776 0.684 rs692780 chr15:78876505 C/G cg06917634 chr15:78832804 PSMA4 -0.68 -5.48 -0.44 2.24e-7 Sudden cardiac arrest; TGCT cis rs2013441 0.965 rs2703790 chr17:20163209 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs72781680 0.898 rs72790310 chr2:24116716 C/T cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs7394190 0.748 rs4746151 chr10:75578720 G/T cg07699608 chr10:75541558 CHCHD1 0.79 4.95 0.41 2.42e-6 Incident atrial fibrillation; TGCT cis rs250677 0.687 rs171636 chr5:148434545 G/A cg18129178 chr5:148520854 ABLIM3 -0.45 -6.06 -0.48 1.54e-8 Breast cancer; TGCT cis rs7698623 0.867 rs4693191 chr4:88797873 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs362272 0.545 rs3135146 chr4:3307638 C/G cg06533319 chr4:3265114 C4orf44 0.24 4.88 0.4 3.24e-6 Serum sulfate level; TGCT cis rs35934224 0.783 rs58195087 chr22:19858547 A/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.22 -0.42 7.16e-7 Glaucoma (primary open-angle); TGCT cis rs9325144 0.650 rs6582624 chr12:38733475 A/T cg26384229 chr12:38710491 ALG10B -0.6 -5.73 -0.46 7.06e-8 Morning vs. evening chronotype; TGCT cis rs513349 1.000 rs513349 chr6:33541719 A/G cg24505687 chr6:33548425 BAK1 0.53 6.9 0.53 2.42e-10 Platelet count; TGCT cis rs12042938 0.600 rs823161 chr1:231775017 G/A cg04892437 chr1:231737901 TSNAX-DISC1 0.46 4.79 0.4 4.68e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs77106637 0.860 rs1552224 chr11:72433098 A/C cg03713592 chr11:72463424 ARAP1 1.21 9.04 0.63 2.56e-15 Type 2 diabetes; TGCT cis rs938554 0.513 rs3775947 chr4:9995240 C/T cg11266682 chr4:10021025 SLC2A9 0.54 4.8 0.4 4.55e-6 Blood metabolite levels; TGCT cis rs9443645 0.901 rs9361466 chr6:79618352 T/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs11040700 chr11:50023832 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs78456975 0.657 rs116217838 chr2:1569173 T/C cg12573674 chr2:1569213 NA -0.49 -5.38 -0.44 3.52e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs17473412 0.609 rs1004434 chr5:122871486 A/T cg15125798 chr5:122621645 NA 0.53 4.93 0.41 2.54e-6 Total body bone mineral density; TGCT cis rs9926296 0.581 rs2108838 chr16:89904426 A/G cg21285383 chr16:89894308 SPIRE2 0.33 4.71 0.39 6.6e-6 Vitiligo; TGCT cis rs826838 1.000 rs826891 chr12:39100824 A/G cg26384229 chr12:38710491 ALG10B -0.85 -8.1 -0.59 4.39e-13 Heart rate; TGCT cis rs2013441 1.000 rs2703816 chr17:20118887 A/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs4819052 1.000 rs2838847 chr21:46670958 G/C cg06618935 chr21:46677482 NA -0.38 -4.89 -0.4 3.07e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7267979 0.934 rs2482913 chr20:25405086 T/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3806843 0.576 rs246007 chr5:140338748 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs425277 0.606 rs377283 chr1:2075570 T/C cg03732007 chr1:2071316 PRKCZ 0.27 6.23 0.49 6.77e-9 Height; TGCT cis rs9341808 0.727 rs4706834 chr6:81012605 G/T cg08355045 chr6:80787529 NA 0.26 4.48 0.37 1.64e-5 Sitting height ratio; TGCT cis rs2404602 0.647 rs11072619 chr15:77043242 A/C cg23625390 chr15:77176239 SCAPER -0.38 -4.79 -0.39 4.75e-6 Blood metabolite levels; TGCT cis rs5750830 0.649 rs2413590 chr22:39790191 G/C cg11247378 chr22:39784982 NA -0.74 -9.72 -0.66 5.95e-17 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7208859 0.673 rs9899349 chr17:29200122 C/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.791 rs34437628 chr4:99029232 C/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2455799 0.613 rs13060772 chr3:15896795 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.73 -0.39 5.89e-6 Mean platelet volume; TGCT cis rs2153535 0.580 rs9505455 chr6:8478622 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT trans rs1496653 0.512 rs35649850 chr3:23481508 A/G cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs425277 1.000 rs425277 chr1:2069172 C/T cg03732007 chr1:2071316 PRKCZ 0.23 4.48 0.37 1.69e-5 Height; TGCT cis rs60154123 0.730 rs679042 chr1:210457122 A/G cg22029157 chr1:209979665 IRF6 0.6 4.46 0.37 1.81e-5 Coronary artery disease; TGCT cis rs6921919 0.583 rs740622 chr6:28398291 T/C cg18815343 chr6:28367644 ZSCAN12 -0.55 -5.21 -0.42 7.65e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs899997 1.000 rs1814880 chr15:79021140 T/C cg04896959 chr15:78267971 NA 0.36 5.31 0.43 4.94e-7 Coronary artery disease or large artery stroke; TGCT cis rs2456568 0.802 rs10831136 chr11:93636860 T/C cg17595323 chr11:93583763 C11orf90 -0.47 -6.44 -0.5 2.38e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs68170813 0.523 rs7777976 chr7:106888594 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT trans rs1005277 0.602 rs1831315 chr10:38473353 T/C cg17830980 chr10:43048298 ZNF37B -0.83 -10.33 -0.68 2.02e-18 Extrinsic epigenetic age acceleration; TGCT cis rs734999 0.545 rs10910111 chr1:2542653 A/G cg18854424 chr1:2615690 NA 0.46 5.32 0.43 4.62e-7 Ulcerative colitis; TGCT cis rs9443645 1.000 rs9443645 chr6:79822924 C/T cg09184832 chr6:79620586 NA -0.47 -5.12 -0.42 1.13e-6 Intelligence (multi-trait analysis); TGCT trans rs77457752 0.690 rs12349396 chr9:13912144 T/C cg18948646 chr4:83674694 SCD5;MIR575 0.55 6.62 0.51 9.75e-10 Breast cancer; TGCT cis rs2404602 0.692 rs7163397 chr15:76940315 A/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT trans rs208520 0.690 rs12209753 chr6:66703951 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs716804 0.691 rs1442738 chr11:10278772 C/G cg17061862 chr11:9590431 NA -0.36 -4.55 -0.38 1.28e-5 Neuroticism; TGCT cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg03264133 chr6:25882463 NA -0.62 -6.65 -0.51 8.55e-10 Blood metabolite levels; TGCT cis rs6782228 1.000 rs34890930 chr3:128329223 T/C cg15113803 chr3:129247119 RHO 0.18 4.7 0.39 6.88e-6 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; TGCT cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs9948 0.655 rs62156232 chr2:97431161 C/A cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs12681288 0.823 rs2701905 chr8:1003482 T/C cg04851639 chr8:1020857 NA -0.36 -6.47 -0.5 2.01e-9 Schizophrenia; TGCT cis rs13242816 1.000 rs56298491 chr7:116116687 C/T cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs2249625 0.584 rs2496506 chr6:72891324 A/C cg08500200 chr6:72892038 RIMS1 -0.42 -4.55 -0.38 1.27e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs35883536 0.609 rs10783142 chr1:101043902 C/G cg10298815 chr1:101004474 GPR88 -0.25 -4.7 -0.39 6.67e-6 Monocyte count; TGCT cis rs2637266 1.000 rs12251543 chr10:78345465 G/A cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT cis rs344364 0.511 rs1742460 chr16:1945441 G/C cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7208859 0.673 rs216411 chr17:28903493 T/C cg04154034 chr17:28927549 LRRC37B2 -0.87 -5.22 -0.42 7.18e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1008375 1.000 rs6818639 chr4:17633049 A/G cg16339924 chr4:17578868 LAP3 0.66 5.49 0.44 2.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7208859 0.623 rs11657777 chr17:29091785 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7959452 0.557 rs899224 chr12:69784774 A/G cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT trans rs7726839 0.561 rs4957048 chr5:583442 G/A cg11887960 chr12:57824829 NA 0.98 7.81 0.57 2.09e-12 Obesity-related traits; TGCT cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.713 rs2328704 chr6:146020494 T/C cg05347473 chr6:146136440 FBXO30 -0.49 -4.67 -0.39 7.63e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.798 rs1349779 chr2:99645055 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.18 -0.49 8.51e-9 Chronic sinus infection; TGCT cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg26531700 chr6:26746687 NA 0.51 4.61 0.38 9.86e-6 Intelligence (multi-trait analysis); TGCT cis rs7584330 0.554 rs74001386 chr2:238425333 T/A cg08992911 chr2:238395768 MLPH 0.73 4.95 0.41 2.37e-6 Prostate cancer; TGCT cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs60871478 0.635 rs4311567 chr7:792295 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.47 4.56 0.38 1.19e-5 Cerebrospinal P-tau181p levels; TGCT cis rs12549025 0.536 rs35742726 chr8:23366942 G/C cg00472375 chr8:23315376 ENTPD4 0.66 5.21 0.42 7.67e-7 Reticulocyte fraction of red cells; TGCT cis rs763121 0.853 rs5750672 chr22:39104168 C/T cg06022373 chr22:39101656 GTPBP1 -0.76 -7.23 -0.54 4.46e-11 Menopause (age at onset); TGCT cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs4455778 0.860 rs9969372 chr7:49067276 A/C cg26309511 chr7:48887640 NA -0.45 -5.32 -0.43 4.78e-7 Lung cancer in never smokers; TGCT cis rs7666738 0.830 rs1967979 chr4:98966201 G/T cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs5769707 0.521 rs7285764 chr22:50058561 T/C cg05373962 chr22:49881684 NA -0.32 -5.46 -0.44 2.46e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7659604 0.540 rs10007956 chr4:122700669 A/T cg19748678 chr4:122722346 EXOSC9 -0.55 -5.55 -0.45 1.62e-7 Type 2 diabetes; TGCT cis rs7727544 0.645 rs272857 chr5:131685297 G/A cg24060327 chr5:131705240 SLC22A5 -0.59 -6.53 -0.51 1.54e-9 Blood metabolite levels; TGCT cis rs7666738 0.830 rs6532723 chr4:99052147 A/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs12599106 0.839 rs3853177 chr16:34498532 A/G cg21548813 chr6:291882 DUSP22 -0.65 -6.89 -0.53 2.46e-10 Menopause (age at onset); TGCT cis rs6088590 0.965 rs6087639 chr20:33443866 G/A cg06115741 chr20:33292138 TP53INP2 0.64 5.21 0.42 7.77e-7 Coronary artery disease; TGCT cis rs1401999 0.966 rs2313212 chr3:183700928 A/G cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs523522 0.962 rs4767905 chr12:120930835 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg08280861 chr8:58055591 NA 0.37 5.03 0.41 1.66e-6 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.901 rs1407045 chr6:26476155 A/G cg02458000 chr6:26745757 NA 0.47 4.46 0.37 1.81e-5 Intelligence (multi-trait analysis); TGCT cis rs2230307 0.536 rs7518943 chr1:100463422 G/T cg24955406 chr1:100503596 HIAT1 0.8 5.73 0.46 7.35e-8 Carotid intima media thickness; TGCT cis rs3806843 0.900 rs2563286 chr5:140125199 T/A cg19875535 chr5:140030758 IK -0.35 -5.92 -0.47 2.89e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7828089 0.522 rs4872484 chr8:22255859 C/T cg12081754 chr8:22256438 SLC39A14 0.31 4.97 0.41 2.18e-6 Verbal declarative memory; TGCT cis rs9291683 0.595 rs35501905 chr4:10053431 C/T cg11266682 chr4:10021025 SLC2A9 0.65 8.68 0.61 1.85e-14 Bone mineral density; TGCT cis rs4665809 1.000 rs7573118 chr2:26308086 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs13102973 0.965 rs4535381 chr4:135861313 A/T cg14419869 chr4:135874104 NA 0.24 4.49 0.37 1.6e-5 Subjective well-being; TGCT trans rs931812 0.825 rs6993937 chr8:101898707 A/G cg20993868 chr7:22813445 NA 0.42 9.22 0.64 9.5e-16 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs9916302 0.904 rs2168785 chr17:37407135 C/T cg07936489 chr17:37558343 FBXL20 -0.64 -5.2 -0.42 7.92e-7 Glomerular filtration rate (creatinine); TGCT cis rs12210905 0.688 rs12209174 chr6:27443952 G/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs9611565 0.512 rs2899347 chr22:42158204 T/C cg17554472 chr22:41940697 POLR3H 0.46 4.69 0.39 7.09e-6 Vitiligo; TGCT cis rs9467773 0.967 rs6924865 chr6:26521353 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs4294134 0.608 rs11535258 chr7:135247547 A/G cg08396481 chr7:135194601 CNOT4 -0.58 -4.68 -0.39 7.53e-6 Paget's disease; TGCT cis rs2730245 1.000 rs2657365 chr7:158722753 A/T cg24397884 chr7:158709396 WDR60 -0.38 -5.16 -0.42 9.34e-7 Height; TGCT cis rs9611565 0.592 rs5751129 chr22:42015765 C/T cg13695892 chr22:41940480 POLR3H 0.83 8.02 0.58 6.86e-13 Vitiligo; TGCT cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs9611565 0.546 rs5758426 chr22:42098763 T/G cg06634786 chr22:41940651 POLR3H 0.84 8.08 0.59 4.86e-13 Vitiligo; TGCT cis rs72781680 1.000 rs72781675 chr2:24232092 G/A cg08917208 chr2:24149416 ATAD2B 0.82 4.92 0.4 2.68e-6 Lymphocyte counts; TGCT cis rs2456568 0.805 rs55784864 chr11:93682887 G/A cg26875233 chr11:93583750 C11orf90 -0.45 -5.65 -0.45 1.04e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7666738 0.830 rs13122456 chr4:98936011 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12200560 0.505 rs211179 chr6:97074103 A/G cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs9486719 1.000 rs12205728 chr6:96891838 T/C cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg10207240 chr12:122356781 WDR66 0.35 4.9 0.4 2.97e-6 Mean corpuscular volume; TGCT cis rs79387448 0.576 rs11902044 chr2:102972534 C/T cg09003973 chr2:102972529 NA 1.47 10.36 0.68 1.69e-18 Gut microbiota (bacterial taxa); TGCT cis rs4665809 1.000 rs4665816 chr2:26305094 G/C cg04944784 chr2:26401820 FAM59B -0.68 -6.04 -0.48 1.7e-8 Gut microbiome composition (summer); TGCT cis rs7772486 0.743 rs62433835 chr6:146032688 C/G cg23711669 chr6:146136114 FBXO30 -0.83 -8.95 -0.63 4.23e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 0.690 rs2029681 chr1:76333846 G/A cg22875332 chr1:76189707 ACADM -0.57 -6.14 -0.48 1.05e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9814567 1.000 rs3846055 chr3:134203973 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -10.02 -0.67 1.12e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6570726 0.935 rs386823 chr6:145841365 C/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7940866 0.803 rs10894307 chr11:130876350 G/A cg05962950 chr11:130786565 SNX19 0.67 6.51 0.5 1.65e-9 Schizophrenia; TGCT cis rs7528419 1.000 rs629301 chr1:109818306 G/T cg00908766 chr1:109817496 CELSR2 0.5 5.08 0.42 1.35e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs739496 0.518 rs10744775 chr12:112096215 T/C cg10833066 chr12:111807467 FAM109A 0.32 4.83 0.4 3.91e-6 Platelet count; TGCT cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg17264618 chr3:40429014 ENTPD3 -0.32 -4.6 -0.38 1.04e-5 Renal cell carcinoma; TGCT cis rs6089584 0.830 rs4925331 chr20:60580174 T/C cg13770153 chr20:60521292 NA -0.53 -7.2 -0.54 5.01e-11 Body mass index; TGCT cis rs9411298 0.550 rs4880192 chr9:139927062 A/G cg14024893 chr9:139943146 ENTPD2 0.36 5.91 0.47 3.08e-8 Monocyte percentage of white cells; TGCT cis rs9443645 0.901 rs9352675 chr6:79612800 G/A cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg18722847 chr3:44754129 ZNF502 -0.4 -4.58 -0.38 1.12e-5 Depressive symptoms; TGCT cis rs7666738 0.753 rs13120995 chr4:98972762 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 0.868 rs8066731 chr17:28523121 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs7772486 0.597 rs6570732 chr6:146245151 G/A cg13319975 chr6:146136371 FBXO30 0.63 5.67 0.45 9.51e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.649 rs4924821 chr17:17735952 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.6 -5.62 -0.45 1.19e-7 Total body bone mineral density; TGCT cis rs2050392 0.517 rs603072 chr10:30755778 C/T cg13289132 chr10:30722225 MAP3K8 0.41 4.93 0.41 2.53e-6 Inflammatory bowel disease; TGCT cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg26513180 chr16:89883248 FANCA 0.76 7.62 0.56 5.81e-12 Vitiligo; TGCT cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs7647973 0.925 rs4955421 chr3:49218888 G/A cg07636037 chr3:49044803 WDR6 0.63 5.09 0.42 1.27e-6 Menarche (age at onset); TGCT cis rs2380220 0.516 rs7748108 chr6:96008082 T/C cg04719120 chr6:96025338 MANEA 0.62 5.01 0.41 1.8e-6 Behavioural disinhibition (generation interaction); TGCT cis rs9467711 0.790 rs41266839 chr6:26409890 G/C cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2201728 0.967 rs28914783 chr4:100231602 C/T cg07219303 chr4:100140905 ADH6 -0.35 -5.14 -0.42 1.04e-6 Cardiac Troponin-T levels; TGCT cis rs1555895 0.599 rs997615 chr10:865214 A/G cg02193355 chr10:851439 NA 0.22 4.78 0.39 4.86e-6 Survival in rectal cancer; TGCT cis rs909674 0.775 rs8138462 chr22:39839670 G/C cg01416388 chr22:39784598 NA -0.73 -6.89 -0.53 2.45e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6570726 0.935 rs419854 chr6:145844085 A/C cg23711669 chr6:146136114 FBXO30 0.69 6.69 0.51 7.01e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4975709 0.589 rs4975746 chr5:1861069 G/A cg04156016 chr5:1868137 NA 0.33 4.66 0.39 8.06e-6 Cardiovascular disease risk factors; TGCT cis rs10876993 0.928 rs1678532 chr12:58055197 T/G cg15848620 chr12:58087721 OS9 -0.73 -5.94 -0.47 2.74e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7100689 0.646 rs1572819 chr10:82112488 A/G cg01528321 chr10:82214614 TSPAN14 0.76 7.57 0.56 7.56e-12 Post bronchodilator FEV1; TGCT cis rs77741769 0.571 rs34009825 chr12:121326183 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.56e-5 Mean corpuscular volume; TGCT cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg27286337 chr10:134555280 INPP5A 0.41 4.9 0.4 2.97e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9467711 0.606 rs34550936 chr6:26361985 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2439831 1.000 rs2256764 chr15:43735763 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 7.11 0.54 8.14e-11 Lung cancer in ever smokers; TGCT cis rs2535633 0.631 rs2245424 chr3:53003021 G/C cg10802521 chr3:52805072 NEK4 0.54 5.83 0.46 4.45e-8 Body mass index; TGCT cis rs7249142 0.549 rs7260127 chr19:19280499 C/T cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B -0.56 -5.54 -0.45 1.69e-7 IgG glycosylation; TGCT cis rs4478858 0.735 rs6687819 chr1:31801112 G/A cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs2562456 0.876 rs2681370 chr19:21736838 T/C cg01304269 chr19:21688519 ZNF429 0.57 4.74 0.39 5.86e-6 Pain; TGCT cis rs11122272 0.701 rs2491402 chr1:231494338 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -6.7 -0.52 6.67e-10 Hemoglobin concentration; TGCT cis rs7666738 0.830 rs35531558 chr4:98938217 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9906944 0.707 rs1523136 chr17:47144532 A/G cg07075026 chr17:47091521 IGF2BP1 -0.45 -4.81 -0.4 4.38e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs36051895 0.560 rs1575281 chr9:5219131 T/C cg02405213 chr9:5042618 JAK2 -0.67 -8.35 -0.6 1.16e-13 Pediatric autoimmune diseases; TGCT cis rs79387448 0.745 rs1159509 chr2:103169073 T/A cg09003973 chr2:102972529 NA 0.95 6.15 0.48 9.95e-9 Gut microbiota (bacterial taxa); TGCT cis rs1056107 0.863 rs7041663 chr9:115002818 T/A cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs2224391 0.628 rs2773319 chr6:5258941 C/T cg09085698 chr6:5261316 LYRM4;FARS2 0.96 6.01 0.47 1.93e-8 Height; TGCT cis rs11190604 1.000 rs10509744 chr10:102271579 C/T cg16342193 chr10:102329863 NA -0.38 -4.84 -0.4 3.77e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2439831 0.867 rs2245176 chr15:43750762 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.81 5.66 0.45 9.81e-8 Lung cancer in ever smokers; TGCT cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.551 rs56886154 chr17:17831473 C/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.91 0.58 1.2e-12 Total body bone mineral density; TGCT cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.45 0.44 2.66e-7 Height; TGCT cis rs36051895 0.632 rs12344116 chr9:5142216 G/A cg02405213 chr9:5042618 JAK2 -0.72 -10.05 -0.67 9.59e-18 Pediatric autoimmune diseases; TGCT cis rs806215 1.000 rs712701 chr7:127251188 T/G cg25922125 chr7:127225783 GCC1 0.58 5.89 0.47 3.35e-8 Type 2 diabetes; TGCT trans rs7615952 0.932 rs7629977 chr3:125649573 T/G cg07211511 chr3:129823064 LOC729375 -0.47 -7.69 -0.57 4e-12 Blood pressure (smoking interaction); TGCT cis rs2956278 0.677 rs2947121 chr12:84681525 G/A cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs9611565 0.802 rs132916 chr22:41806768 C/G cg06634786 chr22:41940651 POLR3H 0.69 6.64 0.51 8.61e-10 Vitiligo; TGCT cis rs6461049 0.800 rs3800913 chr7:2163237 A/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.67 -0.51 7.66e-10 Schizophrenia; TGCT cis rs9894429 0.621 rs7502337 chr17:79588470 T/C cg21028142 chr17:79581711 NPLOC4 0.29 6.08 0.48 1.39e-8 Eye color traits; TGCT cis rs4886920 0.537 rs6495247 chr15:78069431 C/T cg25212270 chr15:78015279 NA 0.23 4.51 0.38 1.47e-5 Neuroticism; TGCT cis rs11190604 1.000 rs4919464 chr10:102221195 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.73 0.39 5.92e-6 Prudent dietary pattern; TGCT cis rs422249 0.547 rs174537 chr11:61552680 G/T cg19610905 chr11:61596333 FADS2 -1.06 -10.7 -0.69 2.47e-19 Trans fatty acid levels; TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs2046867 0.818 rs62249879 chr3:72917171 A/G cg25664220 chr3:72788482 NA -0.54 -6.88 -0.53 2.65e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg02725872 chr8:58115012 NA -0.37 -4.99 -0.41 1.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs7582180 0.629 rs11123827 chr2:100951248 C/G cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2820315 1.000 rs2820314 chr1:201872209 A/C cg12730843 chr1:201915899 LMOD1 -0.27 -4.78 -0.39 4.82e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs782590 0.774 rs782630 chr2:55899425 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.76 0.52 4.79e-10 Metabolic syndrome; TGCT cis rs12369179 1.000 rs12369179 chr12:122963550 C/T cg18578876 chr12:123200353 GPR109B -0.43 -4.75 -0.39 5.47e-6 Age-related diseases, mortality and associated endophenotypes;Age-related disease endophenotypes; TGCT cis rs11122272 0.735 rs2486728 chr1:231535883 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT cis rs7201929 1.000 rs7201929 chr16:28871966 C/T cg09754948 chr16:28834200 ATXN2L 0.63 4.99 0.41 2.03e-6 QT interval; TGCT cis rs6938 0.575 rs12902515 chr15:75160998 G/C cg10253484 chr15:75165896 SCAMP2 -0.53 -4.88 -0.4 3.15e-6 Breast cancer; TGCT cis rs12620999 0.941 rs62183342 chr2:237979140 C/A cg23555395 chr2:238036564 NA 0.27 4.76 0.39 5.28e-6 Systemic lupus erythematosus; TGCT cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs7584330 0.740 rs12471291 chr2:238441751 T/G cg14458575 chr2:238380390 NA 0.41 6.22 0.49 6.9e-9 Prostate cancer; TGCT cis rs704 0.585 rs2227735 chr17:26693258 C/T cg10494684 chr17:26645200 TMEM97 -0.46 -4.95 -0.41 2.33e-6 Osteoprotegerin levels; TGCT cis rs74233809 1.000 rs9633712 chr10:104873761 G/C cg05855489 chr10:104503620 C10orf26 0.82 4.44 0.37 1.97e-5 Birth weight; TGCT cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg01802117 chr1:53393560 SCP2 0.48 5.9 0.47 3.21e-8 Monocyte count; TGCT cis rs9858542 0.537 rs9863142 chr3:49366741 C/G cg00383909 chr3:49044727 WDR6 0.7 4.81 0.4 4.22e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs35306767 0.903 rs12763396 chr10:927357 C/A cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs13191362 0.507 rs2849527 chr6:163117932 G/T cg21926612 chr6:163149169 PACRG;PARK2 0.6 5.7 0.46 8.3e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1023500 0.505 rs2143139 chr22:42614401 G/C cg15557168 chr22:42548783 NA -0.21 -4.8 -0.4 4.45e-6 Schizophrenia; TGCT cis rs8103278 0.507 rs10404220 chr19:46248407 G/A cg11657440 chr19:46296263 DMWD 0.75 7.74 0.57 3.02e-12 Coronary artery disease; TGCT cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs2075671 0.857 rs11772849 chr7:100308412 G/A cg16850897 chr7:100343110 ZAN -0.47 -4.44 -0.37 1.98e-5 Other erythrocyte phenotypes; TGCT cis rs2594989 0.887 rs2454498 chr3:11500953 A/G cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.58e-5 Circulating chemerin levels; TGCT cis rs7044106 0.762 rs1530370 chr9:123424552 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.56 0.38 1.21e-5 Hip circumference adjusted for BMI; TGCT cis rs75059851 0.756 rs11223649 chr11:133840471 T/C cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs2842992 0.830 rs2758320 chr6:160070676 T/G cg11366901 chr6:160182831 ACAT2 1.02 6.71 0.52 6.06e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs10782582 0.593 rs11579752 chr1:76178694 C/T cg03433033 chr1:76189801 ACADM -0.59 -6.73 -0.52 5.46e-10 Daytime sleep phenotypes; TGCT cis rs9790314 0.846 rs899275 chr3:161042104 T/C cg03342759 chr3:160939853 NMD3 -0.5 -5.63 -0.45 1.13e-7 Morning vs. evening chronotype; TGCT cis rs4494114 1.000 rs7539067 chr1:39359694 A/G cg25970120 chr1:39325951 RRAGC -0.62 -6.55 -0.51 1.41e-9 Blood protein levels; TGCT cis rs7666738 0.861 rs5014702 chr4:99052102 C/A cg17366294 chr4:99064904 C4orf37 0.74 7.54 0.56 8.44e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.825 rs13161885 chr5:93071242 A/C cg21475434 chr5:93447410 FAM172A 0.62 4.67 0.39 7.58e-6 Diabetic retinopathy; TGCT cis rs12500482 1.000 rs12500482 chr4:2430235 A/G cg01601518 chr4:2404284 ZFYVE28 -0.29 -4.66 -0.39 8.08e-6 Cognitive function; TGCT cis rs4805272 0.512 rs66830923 chr19:29321277 C/T cg12756686 chr19:29218302 NA 0.63 4.53 0.38 1.34e-5 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs7666738 0.830 rs3896704 chr4:99034252 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11718455 0.920 rs13084408 chr3:44008967 G/A cg08738300 chr3:44038990 NA 0.86 6.55 0.51 1.4e-9 Coronary artery disease; TGCT cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg11502198 chr6:26597334 ABT1 0.53 4.9 0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg18867708 chr6:26865862 GUSBL1 0.4 5.32 0.43 4.75e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6815814 0.950 rs5743789 chr4:38833173 A/T cg02016764 chr4:38805732 TLR1 -0.32 -4.91 -0.4 2.75e-6 Breast cancer; TGCT cis rs2075371 0.501 rs1643057 chr7:134027521 A/G cg11752832 chr7:134001865 SLC35B4 0.59 5.08 0.41 1.36e-6 Mean platelet volume; TGCT cis rs589448 0.538 rs683790 chr12:69751434 T/G cg11871910 chr12:69753446 YEATS4 0.6 5.27 0.43 5.85e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs806215 0.526 rs17151470 chr7:127517965 A/G cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.46e-6 Type 2 diabetes; TGCT trans rs1005277 0.557 rs1854563 chr10:38434961 G/A cg27523141 chr10:43048294 ZNF37B 0.74 8.61 0.61 2.7e-14 Extrinsic epigenetic age acceleration; TGCT cis rs208520 0.690 rs207094 chr6:66799009 G/A cg07460842 chr6:66804631 NA -0.94 -9.91 -0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs9325144 0.534 rs4882350 chr12:38686979 A/G cg26384229 chr12:38710491 ALG10B 0.66 6.12 0.48 1.11e-8 Morning vs. evening chronotype; TGCT cis rs682748 1.000 rs297171 chr5:17150901 A/C cg23987134 chr5:17158319 LOC285696 -0.23 -5.42 -0.44 2.93e-7 Hippocampal atrophy; TGCT cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg08859206 chr1:53392774 SCP2 0.35 5.04 0.41 1.62e-6 Monocyte count; TGCT trans rs6089829 0.851 rs4809460 chr20:61661355 T/C cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg02953382 chr22:24373134 LOC391322 0.82 9.18 0.64 1.24e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs910316 0.967 rs175479 chr14:75561871 A/C cg08847533 chr14:75593920 NEK9 -0.94 -10.04 -0.67 1.03e-17 Height; TGCT cis rs1023500 1.000 rs6002548 chr22:42337040 T/G cg04692870 chr22:42525206 CYP2D6 -0.35 -5.21 -0.42 7.53e-7 Schizophrenia; TGCT trans rs10506458 0.834 rs58821476 chr12:63389425 T/C cg22491629 chr6:157744540 C6orf35 -0.99 -8.5 -0.61 5.08e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs10782582 0.593 rs12129523 chr1:76129223 C/A cg10523679 chr1:76189770 ACADM -0.68 -7.05 -0.53 1.11e-10 Daytime sleep phenotypes; TGCT cis rs10779751 0.960 rs1883965 chr1:11322156 A/G cg08854313 chr1:11322531 MTOR 0.97 9.18 0.64 1.24e-15 Body mass index; TGCT cis rs9467773 1.000 rs1321479 chr6:26501897 C/T cg09904177 chr6:26538194 HMGN4 -0.63 -6.42 -0.5 2.58e-9 Intelligence (multi-trait analysis); TGCT cis rs801193 1.000 rs62466793 chr7:66191517 G/A cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs8017423 0.845 rs8005870 chr14:90723172 A/C cg04374321 chr14:90722782 PSMC1 0.76 7.7 0.57 3.68e-12 Mortality in heart failure; TGCT cis rs7017914 0.869 rs2639954 chr8:71925575 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs2295359 0.824 rs12060309 chr1:67604219 T/C cg03340356 chr1:67600835 NA 0.39 4.65 0.39 8.41e-6 Psoriasis; TGCT cis rs769267 0.965 rs12977937 chr19:19429975 C/G cg02546618 chr19:19431379 KIAA0892;SF4 0.62 5.11 0.42 1.2e-6 Tonsillectomy; TGCT cis rs5769765 0.955 rs2295406 chr22:50260169 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.01 -0.47 1.96e-8 Schizophrenia; TGCT cis rs3796352 1.000 rs75217232 chr3:53132373 A/C cg07884673 chr3:53033167 SFMBT1 0.54 5.76 0.46 6.2e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11190604 0.767 rs11190513 chr10:102165238 A/G cg16005271 chr10:102321736 NA 0.45 4.57 0.38 1.15e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs8141529 0.843 rs1065497 chr22:29279991 C/T cg02153584 chr22:29168773 CCDC117 0.66 4.84 0.4 3.79e-6 Lymphocyte counts; TGCT cis rs2404602 1.000 rs12594212 chr15:76802014 T/A cg26408565 chr15:76604113 ETFA -0.41 -5.28 -0.43 5.48e-7 Blood metabolite levels; TGCT cis rs12477438 0.798 rs9308816 chr2:99637230 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.44 -0.6 6.88e-14 Chronic sinus infection; TGCT cis rs10871290 0.650 rs2288054 chr16:74491733 A/G cg01733217 chr16:74700730 RFWD3 0.58 4.64 0.38 8.59e-6 Breast cancer; TGCT cis rs9818758 0.545 rs11717978 chr3:48969036 T/A cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1008375 1.000 rs1558377 chr4:17650758 A/G cg16339924 chr4:17578868 LAP3 0.67 5.55 0.45 1.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2486288 0.656 rs11637364 chr15:45579238 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.43 -0.44 2.8e-7 Glomerular filtration rate; TGCT cis rs6504663 1.000 rs6504661 chr17:48580126 A/T cg22571038 chr17:48585470 MYCBPAP -0.56 -5.11 -0.42 1.2e-6 Visceral fat; TGCT cis rs7267979 0.816 rs6037158 chr20:25595466 C/A cg16686733 chr20:25566563 NINL 0.51 4.91 0.4 2.81e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6901004 0.570 rs783084 chr6:111477887 T/C cg15721981 chr6:111408429 SLC16A10 0.65 5.43 0.44 2.88e-7 Blood metabolite levels; TGCT cis rs1862618 0.671 rs28397234 chr5:56248428 T/G cg20203395 chr5:56204925 C5orf35 0.53 4.89 0.4 3.03e-6 Initial pursuit acceleration; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg24846343 chr22:24311635 DDTL -0.22 -5.78 -0.46 5.68e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs589448 0.967 rs2617835 chr12:69753420 C/A cg14784868 chr12:69753453 YEATS4 0.9 10.55 0.69 5.67e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs12765878 1.000 rs11191849 chr10:105650880 T/A cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs617219 0.726 rs1275105 chr5:78444148 T/C cg23514016 chr5:78407564 BHMT 0.34 5.15 0.42 9.83e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2688608 0.967 rs2688609 chr10:75658181 A/G cg02947784 chr10:75434997 AGAP5 -0.16 -4.49 -0.37 1.61e-5 Inflammatory bowel disease; TGCT cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 10.59 0.69 4.52e-19 Colorectal cancer; TGCT cis rs11779988 0.545 rs208753 chr8:17814915 A/G cg01800426 chr8:17659068 MTUS1 -0.64 -4.8 -0.4 4.41e-6 Breast cancer; TGCT cis rs10206020 0.885 rs11887527 chr2:1578080 A/G cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg23205692 chr1:25664452 TMEM50A 0.48 5.07 0.41 1.42e-6 Erythrocyte sedimentation rate; TGCT cis rs12477438 0.798 rs2123686 chr2:99690135 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs986417 1.000 rs10148202 chr14:61055940 C/T cg27398547 chr14:60952738 C14orf39 -1.41 -8.43 -0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs4783244 0.897 rs3865188 chr16:82650717 A/T cg09415485 chr16:82663111 CDH13 0.25 4.91 0.4 2.78e-6 Adiponectin levels; TGCT cis rs6565180 1.000 rs11646130 chr16:30376959 T/C cg17640201 chr16:30407289 ZNF48 -0.85 -8.07 -0.59 5.22e-13 Tonsillectomy; TGCT cis rs6545883 0.801 rs778142 chr2:61681428 G/T cg15711740 chr2:61764176 XPO1 -0.53 -4.79 -0.4 4.59e-6 Tuberculosis; TGCT cis rs933688 1.000 rs6869717 chr5:90694797 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.05 0.59 5.84e-13 Smoking behavior; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg15242686 chr22:24348715 GSTTP1 0.42 5.68 0.45 9.1e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17376456 0.825 rs17314825 chr5:93234937 A/G cg21475434 chr5:93447410 FAM172A 0.78 5.28 0.43 5.6e-7 Diabetic retinopathy; TGCT cis rs2456568 0.548 rs7105031 chr11:93661207 C/T cg17595323 chr11:93583763 C11orf90 -0.42 -5.26 -0.43 6.25e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs61990749 0.597 rs176944 chr14:78176211 G/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.65 -0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs10057188 1.000 rs6877631 chr5:77867941 T/C cg06873401 chr5:77792105 LHFPL2 -0.23 -4.53 -0.38 1.39e-5 Pulse pressure; TGCT cis rs6430585 0.941 rs12469551 chr2:136510012 T/G cg07169764 chr2:136633963 MCM6 -0.88 -7.8 -0.57 2.16e-12 Corneal structure; TGCT cis rs73058052 1.000 rs2288920 chr19:50091798 G/T cg09250473 chr19:50168907 IRF3;BCL2L12 0.86 6.53 0.51 1.52e-9 Fibrinogen levels; TGCT cis rs425277 0.628 rs3128340 chr1:2047496 C/G cg24578937 chr1:2090814 PRKCZ -0.26 -6.17 -0.48 9e-9 Height; TGCT cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs7095607 0.560 rs2101484 chr10:69927711 T/C cg18986048 chr10:69913749 MYPN 0.6 6.39 0.5 2.98e-9 Lung function (FVC); TGCT cis rs3935685 0.874 rs35028279 chr15:78003542 T/C cg25212270 chr15:78015279 NA 0.26 5.6 0.45 1.32e-7 Intelligence (multi-trait analysis); TGCT cis rs1857353 1.000 rs61083115 chr1:75909323 G/C cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg06618935 chr21:46677482 NA -0.37 -5.85 -0.47 4.04e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs600231 0.706 rs1111934 chr11:65329392 A/G cg17120908 chr11:65337727 SSSCA1 -0.56 -5.36 -0.43 3.86e-7 Bone mineral density; TGCT cis rs9640161 0.711 rs60268791 chr7:150023800 G/T cg17279839 chr7:150038598 RARRES2 0.43 4.6 0.38 1.02e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs13110410 chr4:98920018 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.11 0.48 1.21e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs763121 0.853 rs6001173 chr22:39015302 A/G cg06022373 chr22:39101656 GTPBP1 0.78 7.99 0.58 8.12e-13 Menopause (age at onset); TGCT cis rs7267979 0.868 rs6138553 chr20:25239233 G/A cg16686733 chr20:25566563 NINL 0.6 6.12 0.48 1.11e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6089829 0.962 rs6089824 chr20:61659207 A/G cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7169223 0.653 rs3743057 chr15:79089007 T/C cg03762349 chr15:79060523 ADAMTS7 -0.24 -4.82 -0.4 4.03e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs6988636 0.710 rs73339623 chr8:124140288 A/G cg27053337 chr8:124217698 FAM83A 0.77 5.55 0.45 1.65e-7 Urinary uromodulin levels; TGCT cis rs28595532 0.920 rs114420700 chr4:119751297 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10782582 0.632 rs11810154 chr1:76239973 C/G cg03433033 chr1:76189801 ACADM -0.46 -4.64 -0.38 8.83e-6 Daytime sleep phenotypes; TGCT cis rs4455778 0.580 rs6583508 chr7:49122331 C/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7727544 0.735 rs273914 chr5:131660431 A/T cg14196790 chr5:131705035 SLC22A5 0.32 4.56 0.38 1.19e-5 Blood metabolite levels; TGCT cis rs9468199 0.523 rs9468152 chr6:27492906 A/C cg11744777 chr6:27799370 HIST1H4K -0.67 -4.51 -0.38 1.49e-5 Parkinson's disease; TGCT cis rs3749237 0.595 rs1464567 chr3:49459252 C/G cg03060546 chr3:49711283 APEH -0.77 -8.78 -0.62 1.11e-14 Resting heart rate; TGCT cis rs1406084 0.636 rs3843320 chr2:154717638 A/C cg25703346 chr2:154729189 GALNT13 0.82 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs1568889 0.838 rs4614434 chr11:28302234 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 10.99 0.7 4.8e-20 Bipolar disorder; TGCT cis rs2073300 1.000 rs6132623 chr20:23442324 T/A cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs8179 0.645 rs7804293 chr7:92287849 T/G cg15732164 chr7:92237376 CDK6 -0.3 -5.11 -0.42 1.17e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT trans rs1814175 0.817 rs7932683 chr11:49983640 G/A cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs801193 0.904 rs4718405 chr7:66254646 A/G cg00343986 chr7:65444356 GUSB 0.24 5.18 0.42 8.62e-7 Aortic root size; TGCT cis rs6681544 0.760 rs4970653 chr1:82429979 T/C cg04226724 chr1:82268649 LPHN2 -0.48 -4.95 -0.41 2.42e-6 Metabolite levels (X-11787); TGCT cis rs751728 0.965 rs9394165 chr6:33731408 G/A cg13859433 chr6:33739653 LEMD2 -0.39 -7.32 -0.55 2.67e-11 Crohn's disease; TGCT cis rs4689388 0.853 rs6817447 chr4:6286847 G/T cg14416269 chr4:6271139 WFS1 0.41 5.42 0.44 2.99e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs11098499 0.738 rs10026493 chr4:120384194 C/G cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7100689 0.646 rs1538823 chr10:82088040 C/A cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs7904368 1.000 rs7904368 chr10:16858587 C/T cg14835575 chr10:16859367 RSU1 0.61 6.84 0.52 3.29e-10 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs2290402 0.572 rs3736087 chr4:876318 C/T cg11315544 chr4:1222440 CTBP1 0.27 4.62 0.38 9.36e-6 Type 2 diabetes; TGCT cis rs34245846 0.769 rs12089942 chr1:154827522 T/C cg06418219 chr1:154948305 SHC1;CKS1B 0.73 5.86 0.47 3.83e-8 Atrial fibrillation; TGCT cis rs7584330 0.704 rs72620821 chr2:238362615 C/A cg14458575 chr2:238380390 NA 0.59 8.88 0.62 6.18e-15 Prostate cancer; TGCT cis rs68170813 0.559 rs17429146 chr7:106964281 A/G cg02696742 chr7:106810147 HBP1 -0.68 -5.52 -0.44 1.9e-7 Coronary artery disease; TGCT cis rs11209002 0.567 rs2755269 chr1:67541065 T/C cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs12142240 0.660 rs7520497 chr1:46824919 C/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs8032315 0.965 rs35346340 chr15:91427872 G/C cg04510874 chr15:91427884 FES 0.52 5.77 0.46 6e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg08859206 chr1:53392774 SCP2 -0.42 -6.8 -0.52 3.92e-10 Monocyte count; TGCT trans rs17685 0.753 rs869806 chr7:75688623 C/T cg19862616 chr7:65841803 NCRNA00174 0.51 8.69 0.62 1.78e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg05368731 chr17:41323189 NBR1 1.2 14.59 0.79 1.08e-28 Menopause (age at onset); TGCT cis rs9517313 0.615 rs4772079 chr13:99090837 C/G cg07423050 chr13:99094983 FARP1 -0.33 -6.67 -0.51 7.67e-10 Neuroticism; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg23131131 chr22:24373011 LOC391322 0.77 7.24 0.55 4.12e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836950 0.565 rs2836943 chr21:40592611 C/T cg17971929 chr21:40555470 PSMG1 -0.51 -4.64 -0.38 8.88e-6 Menarche (age at onset); TGCT cis rs3862260 0.509 rs2281493 chr1:120162787 T/C cg11530693 chr1:120165357 ZNF697 0.2 4.53 0.38 1.38e-5 Systemic lupus erythematosus; TGCT cis rs2070488 0.965 rs2051216 chr3:38562288 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT trans rs731174 0.592 rs12121777 chr1:38188841 C/T cg19725343 chr19:51830960 IGLON5 -0.63 -7.18 -0.54 5.57e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs73198271 0.740 rs28521727 chr8:8647217 T/C cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12134133 1.000 rs4844590 chr1:207496129 C/T cg08855249 chr1:207975363 MIR29C 0.2 4.61 0.38 1e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs1997103 1.000 rs6949222 chr7:55411264 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6088590 0.561 rs2295444 chr20:33173883 C/T cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg15687855 chr3:44754131 ZNF502 -0.52 -6.39 -0.5 2.99e-9 Depressive symptoms; TGCT cis rs2760061 0.819 rs1745416 chr1:228204497 G/A cg02753203 chr1:228287806 NA 0.32 6.14 0.48 1e-8 Diastolic blood pressure; TGCT cis rs854765 0.619 rs1101727 chr17:18016148 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.52 0.56 9.35e-12 Total body bone mineral density; TGCT cis rs17539620 0.624 rs62432738 chr6:154835674 T/C cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs1862618 0.525 rs832403 chr5:56265992 G/T cg24531977 chr5:56204891 C5orf35 0.88 7.52 0.56 9.39e-12 Initial pursuit acceleration; TGCT cis rs2639990 1.000 rs655156 chr18:72898181 T/C cg18449964 chr18:72917101 ZADH2 0.93 6.3 0.49 4.62e-9 Vascular endothelial growth factor levels; TGCT cis rs864537 0.590 rs1214596 chr1:167427170 A/T cg22356347 chr1:167427500 CD247 0.18 4.69 0.39 6.98e-6 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs4766566 0.704 rs11065861 chr12:111752211 A/G cg10833066 chr12:111807467 FAM109A 0.36 6.36 0.5 3.6e-9 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs6543140 0.964 rs2141781 chr2:103082906 G/A cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs858239 0.600 rs6967475 chr7:23128982 C/T cg05602783 chr7:23145260 KLHL7 -0.57 -4.67 -0.39 7.64e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg11494091 chr17:61959527 GH2 -0.61 -15.24 -0.81 3.34e-30 Prudent dietary pattern; TGCT cis rs9942416 0.660 rs2307113 chr5:74998264 C/T cg19683494 chr5:74908142 NA 0.57 6.37 0.5 3.33e-9 Age-related disease endophenotypes; TGCT cis rs79349575 0.783 rs903567 chr17:46980318 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs986417 0.901 rs1884094 chr14:61016933 C/G cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs7824557 0.836 rs2736378 chr8:11119760 G/A cg21775007 chr8:11205619 TDH -0.6 -5.91 -0.47 3.16e-8 Retinal vascular caliber; TGCT cis rs3733585 0.775 rs13124007 chr4:10043931 G/C cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6752107 0.870 rs13418066 chr2:234145944 A/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.89 0.4 3.02e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4273100 0.688 rs4924967 chr17:19172196 T/G cg03910582 chr17:19030146 GRAPL 0.51 6.15 0.48 9.7e-9 Schizophrenia; TGCT cis rs1971256 0.500 rs17081325 chr6:151817992 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.75 -4.58 -0.38 1.1e-5 Endometriosis; TGCT cis rs2486012 0.579 rs4660750 chr1:44250381 T/C cg12908607 chr1:44402522 ARTN -0.71 -5.61 -0.45 1.26e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs35938349 chr4:98974998 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs921968 0.643 rs832801 chr2:219488698 G/A cg02176678 chr2:219576539 TTLL4 0.43 6.11 0.48 1.19e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs17133449 0.696 rs10904325 chr10:4751327 G/T cg04530666 chr10:3759553 NA 0.31 4.74 0.39 5.82e-6 Major depressive disorder; TGCT cis rs6701037 0.566 rs1014555 chr1:175134249 C/T cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg00024416 chr22:24240387 NA -0.39 -6.62 -0.51 9.68e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7937682 0.632 rs11214015 chr11:111719417 A/T cg09085632 chr11:111637200 PPP2R1B -0.8 -7.0 -0.53 1.46e-10 Primary sclerosing cholangitis; TGCT cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.79 7.56 0.56 7.67e-12 Intelligence (multi-trait analysis); TGCT cis rs60843830 1.000 rs11553746 chr2:272203 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.71 6.79 0.52 4.24e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6695640 0.819 rs2762887 chr1:17731440 A/G cg25979543 chr1:17888104 ARHGEF10L -0.25 -4.57 -0.38 1.14e-5 Mean platelet volume; TGCT cis rs7927771 0.832 rs11039212 chr11:47393303 A/T cg21462715 chr11:47870315 NUP160 -0.57 -4.58 -0.38 1.11e-5 Subjective well-being; TGCT trans rs2688608 0.647 rs2633319 chr10:75691247 A/T cg13918328 chr10:52500089 ASAH2B 0.68 6.68 0.51 7.27e-10 Inflammatory bowel disease; TGCT cis rs17221829 0.673 rs1962257 chr11:89380737 G/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs7666738 0.924 rs62318940 chr4:99064768 C/T cg18180107 chr4:99064573 C4orf37 0.57 4.51 0.38 1.49e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs11190604 0.767 rs10509743 chr10:102190406 C/T cg16342193 chr10:102329863 NA -0.4 -5.02 -0.41 1.74e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs362296 0.698 rs362282 chr4:3259671 G/A cg06533319 chr4:3265114 C4orf44 0.24 4.45 0.37 1.86e-5 Parental longevity (mother's age at death); TGCT cis rs1395 0.922 rs11608 chr2:27435374 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.48 -6.35 -0.5 3.72e-9 Blood metabolite levels; TGCT cis rs6570726 0.577 rs441982 chr6:145842848 A/G cg13319975 chr6:146136371 FBXO30 -0.69 -6.08 -0.48 1.38e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6582630 0.555 rs1969362 chr12:38514843 C/T cg13010199 chr12:38710504 ALG10B 0.6 4.77 0.39 5e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9300255 0.602 rs1716168 chr12:123651966 C/G cg00376283 chr12:123451042 ABCB9 -0.72 -5.55 -0.45 1.65e-7 Neutrophil percentage of white cells; TGCT cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg07617317 chr6:118971624 C6orf204 0.46 5.08 0.41 1.36e-6 Diastolic blood pressure; TGCT cis rs7829975 0.606 rs7833171 chr8:8699761 C/T cg06636001 chr8:8085503 FLJ10661 0.71 6.25 0.49 6.17e-9 Mood instability; TGCT cis rs7666738 0.761 rs1456210 chr4:98645932 T/G cg17366294 chr4:99064904 C4orf37 0.57 5.85 0.47 4.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12580194 0.593 rs12099808 chr12:55731178 T/A cg10672482 chr12:55725839 OR6C3 -0.54 -4.77 -0.39 5.17e-6 Cancer; TGCT cis rs8017423 0.647 rs12590712 chr14:90822481 T/C cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs9303542 0.625 rs4793889 chr17:46592352 A/G cg25032089 chr17:46643351 HOXB3 -0.52 -5.56 -0.45 1.6e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6061231 0.571 rs482010 chr20:60927551 A/G cg06026331 chr20:60912101 LAMA5 -0.26 -4.69 -0.39 7.23e-6 Colorectal cancer; TGCT cis rs9435341 0.930 rs61798463 chr1:107565934 G/A cg09367891 chr1:107599246 PRMT6 0.62 5.4 0.44 3.22e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs80282103 0.764 rs10047382 chr10:1102868 T/C cg08668510 chr10:1095578 IDI1 1.01 4.51 0.38 1.48e-5 Glomerular filtration rate (creatinine); TGCT cis rs6598955 0.543 rs881578 chr1:26536141 G/A cg04990556 chr1:26633338 UBXN11 0.82 7.9 0.58 1.31e-12 Obesity-related traits; TGCT cis rs9913156 0.793 rs72835642 chr17:4573407 T/C cg19197139 chr17:4613644 ARRB2 0.86 7.97 0.58 8.69e-13 Lymphocyte counts; TGCT cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg27286337 chr10:134555280 INPP5A 0.42 5.3 0.43 5.03e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12615966 0.932 rs17030310 chr2:105391647 C/T cg16465502 chr2:105461796 NA -0.79 -5.07 -0.41 1.42e-6 Pancreatic cancer; TGCT cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg17264618 chr3:40429014 ENTPD3 0.32 4.72 0.39 6.22e-6 Renal cell carcinoma; TGCT cis rs80282103 0.764 rs7093915 chr10:1107341 A/G cg08668510 chr10:1095578 IDI1 -0.98 -5.31 -0.43 4.82e-7 Glomerular filtration rate (creatinine); TGCT cis rs473651 0.837 rs563458 chr2:239345613 T/A cg21699342 chr2:239360505 ASB1 0.17 4.75 0.39 5.46e-6 Multiple system atrophy; TGCT cis rs9611565 0.506 rs2024567 chr22:41699206 G/C cg06634786 chr22:41940651 POLR3H -0.63 -5.66 -0.45 1.01e-7 Vitiligo; TGCT cis rs4911253 0.509 rs66499347 chr20:31448696 C/T cg13636640 chr20:31349939 DNMT3B -0.78 -8.09 -0.59 4.68e-13 Lymphocyte counts; TGCT cis rs1552244 0.938 rs9873794 chr3:10074153 T/G cg00149659 chr3:10157352 C3orf10 0.98 6.24 0.49 6.21e-9 Alzheimer's disease; TGCT cis rs12541335 0.639 rs4871994 chr8:22206038 G/A cg18135555 chr8:22132992 PIWIL2 0.29 5.84 0.46 4.32e-8 Hypertriglyceridemia; TGCT cis rs2153535 0.580 rs965706 chr6:8464708 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2197308 0.765 rs12824529 chr12:37931656 T/C cg26384229 chr12:38710491 ALG10B 0.87 7.83 0.58 1.85e-12 Morning vs. evening chronotype; TGCT cis rs71435601 0.628 rs4591370 chr2:21383742 C/T cg25035485 chr2:21266500 APOB -0.51 -4.48 -0.37 1.64e-5 Cholesterol, total; TGCT cis rs9325144 0.560 rs11182952 chr12:38636278 C/A cg26384229 chr12:38710491 ALG10B -0.66 -5.98 -0.47 2.23e-8 Morning vs. evening chronotype; TGCT cis rs7786808 0.608 rs6978352 chr7:158209802 T/C cg01191920 chr7:158217561 PTPRN2 0.38 5.73 0.46 7.25e-8 Obesity-related traits; TGCT cis rs7246657 0.943 rs10415937 chr19:37830064 T/G cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.31e-7 Coronary artery calcification; TGCT cis rs1536827 0.541 rs11101814 chr10:135355702 C/G cg12448312 chr10:135032219 KNDC1 -0.49 -4.91 -0.4 2.87e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs35146811 0.700 rs858513 chr7:99825558 G/A cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT trans rs7618501 0.602 rs2526754 chr3:50125996 G/A cg21659725 chr3:3221576 CRBN -0.73 -8.48 -0.61 5.64e-14 Intelligence (multi-trait analysis); TGCT cis rs10089 1.000 rs10463838 chr5:127518305 C/T cg19767477 chr5:127420684 SLC12A2 -0.45 -4.77 -0.39 5.08e-6 Ileal carcinoids; TGCT cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs10946940 0.965 rs6910838 chr6:27515519 A/C cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.63 -0.38 9.22e-6 Systemic lupus erythematosus; TGCT cis rs7666738 0.830 rs17486413 chr4:99060544 G/T cg17366294 chr4:99064904 C4orf37 0.69 6.89 0.53 2.54e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg20007245 chr22:24372913 LOC391322 -0.78 -8.42 -0.6 7.69e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8072100 0.713 rs1912486 chr17:45515167 A/G cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6933660 0.760 rs1825368 chr6:151775259 C/A cg17179660 chr6:151773299 C6orf211;RMND1 -0.54 -4.88 -0.4 3.17e-6 Menarche (age at onset); TGCT cis rs28595532 0.920 rs115320476 chr4:119759680 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs1499614 1.000 rs1267817 chr7:66110040 G/T cg18252515 chr7:66147081 NA -1.23 -7.53 -0.56 9.12e-12 Gout; TGCT cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.58 -5.83 -0.46 4.44e-8 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.673 rs73265624 chr17:29232066 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6831352 0.918 rs29001231 chr4:100046680 T/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs9733 0.519 rs3768005 chr1:150680988 A/T cg04414720 chr1:150670196 GOLPH3L 0.38 5.0 0.41 1.88e-6 Tonsillectomy; TGCT cis rs6674176 0.932 rs7412307 chr1:44433864 C/G cg12908607 chr1:44402522 ARTN 0.74 8.47 0.61 5.88e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2070433 0.539 rs56157650 chr21:47957959 T/C cg12379764 chr21:47803548 PCNT 0.54 5.44 0.44 2.69e-7 Lymphocyte counts; TGCT cis rs2692947 0.673 rs1168965 chr2:96787899 C/G cg23100626 chr2:96804247 ASTL -0.41 -4.99 -0.41 1.96e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2338224 1.000 rs10942301 chr5:71745457 G/A cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs7017914 0.875 rs2732107 chr8:71925308 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.19e-6 Bone mineral density; TGCT cis rs4727027 0.933 rs1468369 chr7:148839840 G/C cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs739496 0.579 rs12296574 chr12:112322777 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT trans rs6762477 0.748 rs34877766 chr3:50234126 A/G cg21659725 chr3:3221576 CRBN 0.67 7.32 0.55 2.78e-11 Menarche (age at onset); TGCT cis rs72634258 0.554 rs1012477 chr1:7858135 C/G cg26816564 chr1:7831052 VAMP3 -0.9 -6.76 -0.52 4.86e-10 Inflammatory bowel disease; TGCT cis rs6977660 0.652 rs12673842 chr7:19747437 T/C cg07541023 chr7:19748670 TWISTNB 1.15 7.28 0.55 3.33e-11 Thyroid stimulating hormone; TGCT cis rs938554 0.513 rs4529048 chr4:9997112 G/T cg11266682 chr4:10021025 SLC2A9 0.62 4.92 0.4 2.7e-6 Blood metabolite levels; TGCT cis rs931127 0.624 rs2306364 chr11:65412467 G/A cg17480646 chr11:65405466 SIPA1 -0.51 -6.44 -0.5 2.33e-9 Systemic lupus erythematosus; TGCT cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg06640241 chr16:89574553 SPG7 0.8 9.04 0.63 2.63e-15 Multiple myeloma (IgH translocation); TGCT cis rs7647973 0.710 rs11130208 chr3:49615624 G/T cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT trans rs941408 1.000 rs2260416 chr19:2796355 G/A cg22153745 chr1:153894579 GATAD2B -0.64 -7.01 -0.53 1.39e-10 Total cholesterol levels; TGCT cis rs7727544 0.661 rs273900 chr5:131694606 G/A cg24060327 chr5:131705240 SLC22A5 -0.57 -6.43 -0.5 2.55e-9 Blood metabolite levels; TGCT cis rs7267979 0.816 rs6138593 chr20:25504492 A/G cg14121845 chr20:25566513 NINL 0.46 4.76 0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10751667 0.857 rs6597961 chr11:976677 T/C cg06064525 chr11:970664 AP2A2 -0.33 -6.51 -0.5 1.71e-9 Alzheimer's disease (late onset); TGCT trans rs916888 0.738 rs199515 chr17:44856641 C/G cg07870213 chr5:140052090 DND1 -0.59 -6.89 -0.53 2.5e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7666738 0.716 rs13136721 chr4:99085602 G/A cg17366294 chr4:99064904 C4orf37 0.68 6.69 0.51 6.92e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4389656 0.857 rs2279657 chr5:6737571 A/G cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs10031751 chr4:98939134 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs40363 1.000 rs1690444 chr16:3518350 G/A cg05754148 chr16:3507555 NAT15 0.48 4.68 0.39 7.32e-6 Tuberculosis; TGCT cis rs12541335 0.639 rs4871994 chr8:22206038 G/A cg07298985 chr8:22133076 PIWIL2 0.33 5.14 0.42 1.04e-6 Hypertriglyceridemia; TGCT cis rs6722750 0.818 rs13411753 chr2:64394417 A/G cg22352474 chr2:64371530 PELI1 0.65 6.02 0.48 1.79e-8 Neuroticism; TGCT cis rs832540 0.669 rs832539 chr5:56199386 A/C cg24531977 chr5:56204891 C5orf35 -0.68 -6.83 -0.52 3.47e-10 Coronary artery disease; TGCT cis rs524281 0.861 rs10896086 chr11:65914764 T/A cg00563793 chr11:65837595 PACS1 0.57 4.68 0.39 7.4e-6 Electroencephalogram traits; TGCT cis rs6570726 0.764 rs9386125 chr6:145911677 C/T cg05347473 chr6:146136440 FBXO30 0.51 4.75 0.39 5.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3540 0.512 rs8033818 chr15:91075535 C/T cg22089800 chr15:90895588 ZNF774 -0.74 -7.58 -0.56 7.14e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2439831 0.850 rs12441984 chr15:44126285 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs2153535 0.521 rs6939827 chr6:8461360 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs11175492 0.528 rs11175480 chr12:65028492 G/A cg18624581 chr12:65153313 GNS -0.85 -4.64 -0.38 8.76e-6 Platelet count; TGCT cis rs10479542 0.806 rs4700835 chr5:178976313 A/G cg19723775 chr5:179050963 HNRNPH1 0.48 4.64 0.38 8.71e-6 Lung cancer; TGCT cis rs7822232 1.000 rs6558296 chr8:145143802 G/A cg06239191 chr8:145163136 KIAA1875 -0.88 -6.45 -0.5 2.26e-9 Blood metabolite levels; TGCT cis rs7824557 0.724 rs2251473 chr8:11177126 C/A cg21775007 chr8:11205619 TDH 0.56 5.14 0.42 1.05e-6 Retinal vascular caliber; TGCT cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg05896524 chr21:47604654 C21orf56 0.4 4.5 0.37 1.54e-5 Testicular germ cell tumor; TGCT cis rs12497850 0.931 rs62262517 chr3:49134914 T/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.51 0.44 2e-7 Parkinson's disease; TGCT cis rs7249142 0.549 rs12975253 chr19:19279745 A/C cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.62 0.45 1.18e-7 IgG glycosylation; TGCT cis rs7666738 0.830 rs7679961 chr4:99000202 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10751667 1.000 rs6597972 chr11:928402 C/T cg06064525 chr11:970664 AP2A2 -0.33 -6.4 -0.5 2.96e-9 Alzheimer's disease (late onset); TGCT cis rs854765 0.583 rs12452254 chr17:17829434 G/A cg09796270 chr17:17721594 SREBF1 0.27 5.53 0.44 1.84e-7 Total body bone mineral density; TGCT trans rs561341 0.941 rs8066156 chr17:30361629 A/G cg20587970 chr11:113659929 NA -0.96 -12.63 -0.75 5.23e-24 Hip circumference adjusted for BMI; TGCT cis rs425277 0.606 rs16824792 chr1:2039521 G/T cg03732007 chr1:2071316 PRKCZ -0.26 -5.92 -0.47 2.9e-8 Height; TGCT cis rs7010267 0.602 rs7822098 chr8:120020129 A/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9910055 0.529 rs368328 chr17:42170289 G/A cg19774624 chr17:42201019 HDAC5 0.77 6.98 0.53 1.61e-10 Total body bone mineral density; TGCT cis rs589448 0.902 rs2603090 chr12:69777188 G/A cg11871910 chr12:69753446 YEATS4 0.89 10.53 0.69 6.39e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs7829975 0.567 rs6601273 chr8:8796519 T/G cg15556689 chr8:8085844 FLJ10661 -0.69 -6.14 -0.48 1.01e-8 Mood instability; TGCT cis rs9486719 0.857 rs13208321 chr6:96860354 C/T cg06623918 chr6:96969491 KIAA0776 -0.97 -9.58 -0.65 1.3e-16 Migraine;Coronary artery disease; TGCT cis rs9291683 0.620 rs4383618 chr4:10125151 T/C cg00071950 chr4:10020882 SLC2A9 -0.43 -4.7 -0.39 6.69e-6 Bone mineral density; TGCT cis rs2070488 0.965 rs7372386 chr3:38484175 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 9.68 0.66 7.36e-17 Electrocardiographic conduction measures; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg08859206 chr1:53392774 SCP2 -0.43 -6.71 -0.52 6.34e-10 Monocyte count; TGCT cis rs9467711 0.606 rs9393705 chr6:26361011 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4862307 0.514 rs7696176 chr4:185014390 A/G cg06737308 chr4:185021514 ENPP6 0.47 7.56 0.56 7.6e-12 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs12497850 0.765 rs12487580 chr3:49182932 G/A cg07636037 chr3:49044803 WDR6 0.94 10.1 0.67 7.08e-18 Parkinson's disease; TGCT cis rs7647973 0.593 rs59684465 chr3:49874246 C/T cg03034192 chr3:50606346 HEMK1;C3orf18 -0.34 -4.51 -0.38 1.5e-5 Menarche (age at onset); TGCT cis rs9583531 0.660 rs34523940 chr13:111350205 C/T cg15747390 chr13:111297551 CARS2 0.73 5.03 0.41 1.65e-6 Coronary artery disease; TGCT cis rs910316 1.000 rs12889472 chr14:75543979 A/G cg08847533 chr14:75593920 NEK9 0.96 10.54 0.69 6.25e-19 Height; TGCT cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 1.000 rs514406 chr1:53330458 A/G cg08859206 chr1:53392774 SCP2 -0.4 -4.52 -0.38 1.4e-5 Monocyte count; TGCT cis rs9611565 0.559 rs13056262 chr22:42081921 A/G cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Vitiligo; TGCT cis rs7267979 0.816 rs405822 chr20:25501314 A/G cg14121845 chr20:25566513 NINL 0.46 4.76 0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10028773 0.556 rs4473640 chr4:120260437 G/A cg09307838 chr4:120376055 NA 0.53 5.16 0.42 9.36e-7 Educational attainment; TGCT cis rs12950390 0.853 rs59513807 chr17:45867925 G/A cg06532163 chr17:45867833 NA 0.37 5.96 0.47 2.45e-8 IgG glycosylation; TGCT cis rs9916302 0.851 rs6503518 chr17:37660469 A/G cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs9291683 0.588 rs3756237 chr4:10013378 G/A cg11266682 chr4:10021025 SLC2A9 0.73 11.04 0.7 3.63e-20 Bone mineral density; TGCT cis rs2153535 0.541 rs4637688 chr6:8446501 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.29e-6 Motion sickness; TGCT cis rs2404602 0.716 rs17460201 chr15:76673627 C/T cg22467129 chr15:76604101 ETFA 0.56 6.56 0.51 1.32e-9 Blood metabolite levels; TGCT cis rs8078723 0.933 rs4794822 chr17:38156712 C/T cg17467752 chr17:38218738 THRA 0.55 5.34 0.43 4.24e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7659604 0.502 rs13108419 chr4:122687238 A/G cg05802129 chr4:122689817 NA 0.29 4.46 0.37 1.84e-5 Type 2 diabetes; TGCT cis rs11662586 0.517 rs11663082 chr18:77713494 C/T cg20368463 chr18:77673604 PQLC1 0.6 7.0 0.53 1.39e-10 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs13082711 0.522 rs574955 chr3:27351000 T/C cg02860705 chr3:27208620 NA 0.32 5.24 0.43 6.6e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs9388451 0.903 rs7758115 chr6:126061502 C/T cg05901451 chr6:126070800 HEY2 -0.97 -12.85 -0.76 1.53e-24 Brugada syndrome; TGCT cis rs11264213 0.901 rs631202 chr1:36449099 G/C cg26235710 chr1:36184717 C1orf216 0.97 4.55 0.38 1.25e-5 Schizophrenia; TGCT cis rs12681287 0.604 rs28378899 chr8:87434500 G/C cg27223183 chr8:87520930 FAM82B 0.89 6.43 0.5 2.54e-9 Caudate activity during reward; TGCT cis rs739496 0.615 rs11609628 chr12:112217208 G/A cg10833066 chr12:111807467 FAM109A 0.36 4.67 0.39 7.74e-6 Platelet count; TGCT cis rs75229567 0.618 rs10219700 chr12:70201730 A/G cg10114359 chr12:70132523 RAB3IP -1.06 -5.95 -0.47 2.6e-8 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs362296 0.698 rs3095081 chr4:3263776 C/T cg06533319 chr4:3265114 C4orf44 0.23 4.85 0.4 3.67e-6 Parental longevity (mother's age at death); TGCT cis rs7666738 0.830 rs6846739 chr4:99016647 G/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs801193 0.569 rs4717315 chr7:66178325 C/T cg11764359 chr7:65958608 NA 0.54 4.85 0.4 3.67e-6 Aortic root size; TGCT cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1729951 0.575 rs16844362 chr3:136704008 T/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.24e-7 Neuroticism; TGCT cis rs910316 1.000 rs12435391 chr14:75601737 A/G cg08847533 chr14:75593920 NEK9 0.92 9.91 0.66 2.1e-17 Height; TGCT cis rs7914558 0.966 rs10786719 chr10:104637992 C/T cg15744005 chr10:104629667 AS3MT 0.41 5.3 0.43 5.14e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12950390 0.853 rs8071192 chr17:45856141 A/G cg06532163 chr17:45867833 NA 0.37 5.89 0.47 3.46e-8 IgG glycosylation; TGCT cis rs8180040 0.932 rs11711265 chr3:47558448 T/C cg27129171 chr3:47204927 SETD2 0.62 7.36 0.55 2.26e-11 Colorectal cancer; TGCT cis rs559928 0.569 rs7103915 chr11:63944370 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.75 -4.85 -0.4 3.58e-6 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs4972806 0.668 rs2072588 chr2:177042930 G/C cg13092806 chr2:177043255 NA 0.6 5.24 0.43 6.62e-7 IgG glycosylation; TGCT cis rs9902453 0.967 rs8082175 chr17:28430303 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.57 0.51 1.22e-9 Coffee consumption (cups per day); TGCT cis rs34684276 1 rs34684276 chr15:78813155 G/A cg18825076 chr15:78729989 IREB2 -0.3 -4.5 -0.37 1.58e-5 Nicotine dependence;Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs6748734 0.901 rs6720357 chr2:241830296 A/C cg04034577 chr2:241836375 C2orf54 -0.4 -6.32 -0.49 4.22e-9 Urinary metabolites; TGCT cis rs6490294 0.904 rs60217649 chr12:112410920 C/T cg10833066 chr12:111807467 FAM109A 0.39 5.53 0.44 1.83e-7 Mean platelet volume; TGCT trans rs17685 0.725 rs1044483 chr7:75659815 T/C cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.78 -0.62 1.07e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2463822 1.000 rs1881534 chr11:62085083 A/G cg06239285 chr11:62104954 ASRGL1 0.95 6.58 0.51 1.18e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2486012 1.000 rs2486014 chr1:44419546 T/C cg12908607 chr1:44402522 ARTN 0.77 6.02 0.48 1.79e-8 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.555 rs11613249 chr12:38519339 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.68 0.57 4.16e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs6598955 0.671 rs10159433 chr1:26618370 A/G cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT trans rs10506458 0.915 rs56321182 chr12:63392023 C/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs986417 0.901 rs11158292 chr14:61043183 G/T cg27398547 chr14:60952738 C14orf39 1.48 11.08 0.71 2.96e-20 Gut microbiota (bacterial taxa); TGCT cis rs68170813 0.559 rs12533767 chr7:106860245 A/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs2456568 0.867 rs7935801 chr11:93658000 G/A cg16099599 chr11:93583650 C11orf90 -0.41 -4.78 -0.39 4.87e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7647973 1.000 rs1009051 chr3:49521549 G/A cg05785598 chr3:49045655 WDR6 0.37 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs9611565 0.512 rs4822052 chr22:42193741 G/A cg03806693 chr22:41940476 POLR3H -0.96 -9.99 -0.67 1.36e-17 Vitiligo; TGCT cis rs2842992 0.830 rs2758312 chr6:160153452 G/A cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs6089829 0.962 rs6122352 chr20:61668284 T/C cg18188782 chr20:61659543 NA 0.44 5.29 0.43 5.3e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs1461503 0.932 rs6589962 chr11:122843535 G/A cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs478304 0.903 rs61895677 chr11:65549415 T/C cg27068330 chr11:65405492 SIPA1 0.74 7.34 0.55 2.48e-11 Acne (severe); TGCT cis rs17376456 0.877 rs10060462 chr5:93455073 C/T cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs35146811 0.700 rs4729579 chr7:99780282 C/G cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.57 -5.77 -0.46 5.91e-8 Electroencephalogram traits; TGCT cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089584 0.528 rs881994 chr20:60623931 G/A cg06108461 chr20:60628389 TAF4 -0.45 -5.37 -0.43 3.78e-7 Body mass index; TGCT cis rs60154123 0.505 rs76101197 chr1:210044089 T/C cg23283495 chr1:209979779 IRF6 0.67 4.99 0.41 1.96e-6 Coronary artery disease; TGCT cis rs10751667 1.000 rs10902246 chr11:953674 T/C cg06064525 chr11:970664 AP2A2 -0.33 -6.49 -0.5 1.83e-9 Alzheimer's disease (late onset); TGCT cis rs10751667 0.666 rs7396059 chr11:970490 C/A cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs6088590 1.000 rs6087626 chr20:33347328 C/T cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs10131894 0.529 rs10162358 chr14:75429593 A/G cg06637938 chr14:75390232 RPS6KL1 0.55 4.77 0.39 5.16e-6 Coronary artery disease; TGCT cis rs7954584 0.616 rs10743185 chr12:122356435 G/A cg13699009 chr12:122356056 WDR66 0.32 7.33 0.55 2.6e-11 Mean corpuscular volume; TGCT cis rs7954584 0.567 rs11043251 chr12:122373279 C/T cg21016266 chr12:122356598 WDR66 0.53 6.62 0.51 9.84e-10 Mean corpuscular volume; TGCT cis rs12579753 1.000 rs7963577 chr12:82174115 T/C cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs732765 1.000 rs10134885 chr14:75373475 C/T cg06637938 chr14:75390232 RPS6KL1 0.62 5.37 0.43 3.7e-7 Non-small cell lung cancer; TGCT cis rs9911578 1.000 rs4793952 chr17:56608465 C/T cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs734999 0.967 rs7515633 chr1:2496653 A/G cg18854424 chr1:2615690 NA 0.47 5.78 0.46 5.71e-8 Ulcerative colitis; TGCT cis rs185694 1.000 rs595449 chr13:30896852 T/C cg07600127 chr13:30881527 KATNAL1 -0.82 -6.75 -0.52 4.95e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs1355023 0.547 rs7767248 chr6:106228397 G/A cg17356964 chr6:106582638 NA 0.26 4.92 0.4 2.7e-6 Age-related macular degeneration; TGCT cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg10295955 chr4:187884368 NA -0.96 -14.48 -0.79 2.04e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 0.692 rs12910734 chr15:77149931 A/G cg26408565 chr15:76604113 ETFA -0.36 -4.54 -0.38 1.33e-5 Blood metabolite levels; TGCT cis rs4919694 1.000 rs12266291 chr10:104806884 G/A cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.44 0.44 2.75e-7 Platelet count; TGCT cis rs919433 0.680 rs2565163 chr2:198354414 T/C cg00792783 chr2:198669748 PLCL1 0.52 4.73 0.39 5.98e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs9381040 0.655 rs6939989 chr6:41020205 A/G cg03526776 chr6:41159608 TREML2 0.27 5.28 0.43 5.66e-7 Alzheimer's disease (late onset); TGCT cis rs7829975 0.688 rs7817376 chr8:8380530 C/T cg06636001 chr8:8085503 FLJ10661 -0.77 -7.37 -0.55 2.13e-11 Mood instability; TGCT cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11190604 1.000 rs7070776 chr10:102264672 A/G cg23241863 chr10:102295624 HIF1AN 0.7 5.38 0.43 3.59e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs78487399 0.808 rs1388387 chr2:43736969 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.84 -0.4 3.79e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3820068 0.603 rs72645900 chr1:15931980 A/T cg05660106 chr1:15850417 CASP9 0.74 7.27 0.55 3.53e-11 Systolic blood pressure; TGCT cis rs3820928 0.934 rs66959645 chr2:227761582 C/A cg11843606 chr2:227700838 RHBDD1 -0.51 -4.51 -0.38 1.47e-5 Pulmonary function; TGCT cis rs981844 0.796 rs17030437 chr4:154704225 A/C cg14289246 chr4:154710475 SFRP2 -1.07 -9.0 -0.63 3.18e-15 Response to statins (LDL cholesterol change); TGCT cis rs10504229 0.953 rs114806125 chr8:58182416 C/T cg21724239 chr8:58056113 NA 0.33 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115853212 chr4:119765354 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs4951018 0.821 rs11240547 chr1:205632932 A/G cg26354017 chr1:205819088 PM20D1 0.4 4.59 0.38 1.06e-5 Prostate-specific antigen levels; TGCT cis rs7582180 0.627 rs2099611 chr2:101021090 A/G cg14675211 chr2:100938903 LONRF2 0.47 4.47 0.37 1.75e-5 Intelligence (multi-trait analysis); TGCT trans rs1496653 0.602 rs35347265 chr3:23420397 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs28595532 0.920 rs116046128 chr4:119741990 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs10984561 0.881 rs73540223 chr9:122250259 A/G cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs6430585 0.527 rs2254780 chr2:136435526 C/T cg07169764 chr2:136633963 MCM6 0.92 8.17 0.59 3.08e-13 Corneal structure; TGCT cis rs4711350 0.765 rs756138 chr6:33755711 G/C cg18005901 chr6:33739558 LEMD2 -0.59 -6.61 -0.51 1.01e-9 Schizophrenia; TGCT cis rs7917772 0.636 rs7911747 chr10:104528890 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.6 -4.92 -0.4 2.67e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3796352 1.000 rs71301804 chr3:53073314 C/A cg15956490 chr3:53032818 SFMBT1 0.59 6.75 0.52 5.19e-10 Immune reponse to smallpox (secreted IL-2); TGCT trans rs7618501 0.521 rs2352984 chr3:49948728 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.83 8.48 0.61 5.54e-14 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.501 rs35994303 chr21:40686020 C/T cg06238570 chr21:40685208 BRWD1 -0.63 -6.4 -0.5 2.96e-9 Menarche (age at onset); TGCT cis rs8103278 1.000 rs1548029 chr19:46309203 A/C cg11657440 chr19:46296263 DMWD -0.59 -5.63 -0.45 1.17e-7 Coronary artery disease; TGCT cis rs7104764 0.507 rs7121085 chr11:258523 A/G cg18336825 chr11:236787 PSMD13;SIRT3 0.76 5.68 0.45 8.96e-8 Menarche (age at onset); TGCT cis rs4886920 0.694 rs12902298 chr15:78085418 C/T cg25212270 chr15:78015279 NA -0.23 -4.75 -0.39 5.57e-6 Neuroticism; TGCT cis rs782590 0.837 rs809732 chr2:55914621 T/C cg03859395 chr2:55845619 SMEK2 0.81 9.36 0.64 4.35e-16 Metabolic syndrome; TGCT cis rs7044106 0.762 rs1324473 chr9:123404610 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.42 -4.46 -0.37 1.8e-5 Hip circumference adjusted for BMI; TGCT cis rs360798 0.532 rs189671 chr2:62959308 T/A cg17519650 chr2:63277830 OTX1 -0.54 -4.58 -0.38 1.14e-5 Coronary artery disease; TGCT cis rs931127 0.502 rs1466462 chr11:65419364 C/G cg12758867 chr11:65354231 EHBP1L1 -0.26 -5.09 -0.42 1.3e-6 Systemic lupus erythematosus; TGCT cis rs2645424 0.635 rs62495697 chr8:11709007 G/A cg21281001 chr8:11725306 CTSB 0.55 4.49 0.37 1.64e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs4505848 0.606 rs7676523 chr4:123523279 G/A cg10583651 chr4:123538969 IL21 -0.36 -5.27 -0.43 5.97e-7 Type 1 diabetes; TGCT cis rs1008375 1.000 rs2872959 chr4:17677163 G/A cg10189774 chr4:17578691 LAP3 -0.56 -4.95 -0.41 2.37e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2404602 0.967 rs7174096 chr15:77072400 A/G cg26408565 chr15:76604113 ETFA -0.37 -4.65 -0.39 8.34e-6 Blood metabolite levels; TGCT cis rs2730245 1.000 rs2730241 chr7:158723014 T/C cg24397884 chr7:158709396 WDR60 -0.37 -4.98 -0.41 2.1e-6 Height; TGCT cis rs7674212 0.539 rs6854709 chr4:104129786 A/G cg16532752 chr4:104119610 CENPE -0.61 -5.49 -0.44 2.17e-7 Type 2 diabetes; TGCT cis rs2762353 0.603 rs12201071 chr6:25778055 C/T cg03517284 chr6:25882590 NA 0.5 4.96 0.41 2.24e-6 Blood metabolite levels; TGCT cis rs7264396 0.690 rs2425178 chr20:34446395 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.98 0.41 2.05e-6 Bipolar disorder; TGCT cis rs4700695 0.841 rs36301 chr5:65348940 A/G cg21114390 chr5:65439923 SFRS12 0.62 4.57 0.38 1.18e-5 Facial morphology (factor 19); TGCT cis rs35264875 1.000 rs72919432 chr11:68829954 C/T cg02660097 chr11:68866761 NA 0.32 4.8 0.4 4.55e-6 Blond vs. brown hair color; TGCT trans rs731174 0.559 rs10908375 chr1:38194094 G/C cg19725343 chr19:51830960 IGLON5 -0.63 -7.18 -0.54 5.57e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs9916302 0.706 rs8069074 chr17:37685401 C/T cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs6860806 0.507 rs169256 chr5:131688533 A/G cg24060327 chr5:131705240 SLC22A5 -0.68 -7.33 -0.55 2.64e-11 Breast cancer; TGCT cis rs7824557 0.527 rs11785394 chr8:11238029 C/T cg21775007 chr8:11205619 TDH -0.6 -5.61 -0.45 1.23e-7 Retinal vascular caliber; TGCT cis rs35883536 0.609 rs10783142 chr1:101043902 C/G cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.11e-12 Monocyte count; TGCT cis rs9549367 0.713 rs9549691 chr13:113861606 A/C cg09473364 chr13:112927190 NA -0.31 -4.62 -0.38 9.3e-6 Platelet distribution width; TGCT cis rs916888 0.610 rs199453 chr17:44800946 C/T cg17911788 chr17:44343683 NA -0.48 -5.66 -0.45 9.83e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12049351 0.774 rs12125978 chr1:229627722 T/C cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs11677370 0.561 rs10191326 chr2:3827524 G/C cg17052675 chr2:3827356 NA -0.43 -7.81 -0.57 2.04e-12 Type 2 diabetes; TGCT cis rs6912958 0.667 rs7746545 chr6:88090225 A/G cg10393598 chr6:87862264 NA -0.31 -4.5 -0.37 1.56e-5 Monocyte percentage of white cells; TGCT cis rs597539 0.652 rs482172 chr11:68668437 C/A cg21862992 chr11:68658383 NA 0.47 6.61 0.51 1.03e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3796352 1.000 rs10510761 chr3:52965255 A/G cg15956490 chr3:53032818 SFMBT1 -0.63 -6.65 -0.51 8.26e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9486715 1.000 rs3798297 chr6:97062835 C/T cg18709589 chr6:96969512 KIAA0776 -0.78 -7.13 -0.54 7.19e-11 Headache; TGCT cis rs1568079 0.516 rs1571424 chr10:125220311 G/A cg02353154 chr10:124578028 NA -0.37 -4.72 -0.39 6.34e-6 Body mass index; TGCT cis rs12681288 0.550 rs4410933 chr8:959581 A/G cg04851639 chr8:1020857 NA -0.27 -4.44 -0.37 1.94e-5 Schizophrenia; TGCT cis rs2842992 0.830 rs2842966 chr6:160141592 C/T cg11366901 chr6:160182831 ACAT2 0.95 6.33 0.49 4.14e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs4642101 0.618 rs11128614 chr3:12819212 A/G cg05775895 chr3:12838266 CAND2 0.89 9.52 0.65 1.87e-16 QRS complex (12-leadsum); TGCT cis rs9486719 0.857 rs11751075 chr6:97065751 G/A cg06623918 chr6:96969491 KIAA0776 -1.06 -9.8 -0.66 3.95e-17 Migraine;Coronary artery disease; TGCT cis rs6088580 0.634 rs6059878 chr20:33087166 A/T cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs7255374 0.566 rs7255904 chr19:41529020 C/T cg27089200 chr19:41531976 NA 0.49 6.58 0.51 1.18e-9 DDT metabolite (p,p'-DDE levels); TGCT cis rs911555 0.755 rs2756128 chr14:103974964 C/T cg12935359 chr14:103987150 CKB 0.33 4.57 0.38 1.15e-5 Intelligence (multi-trait analysis); TGCT cis rs9368481 0.761 rs7775041 chr6:27009512 T/A cg18867708 chr6:26865862 GUSBL1 -0.43 -5.63 -0.45 1.15e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9921338 0.961 rs77552156 chr16:11426399 C/A cg00044050 chr16:11439710 C16orf75 -0.88 -6.75 -0.52 5.08e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg03517284 chr6:25882590 NA -0.66 -5.82 -0.46 4.67e-8 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.800 rs62296338 chr4:17613425 G/T cg10189774 chr4:17578691 LAP3 0.63 5.29 0.43 5.25e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6866344 0.697 rs11748497 chr5:178130012 C/G cg03877680 chr5:178157825 ZNF354A 0.72 5.84 0.46 4.2e-8 Neutrophil percentage of white cells; TGCT cis rs864537 0.676 rs1773560 chr1:167421763 A/G cg22356347 chr1:167427500 CD247 -0.22 -5.47 -0.44 2.35e-7 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs964184 0.638 rs3741298 chr11:116657561 C/T cg23217865 chr11:117376295 DSCAML1 0.27 4.44 0.37 2e-5 Age-related disease endophenotypes;Metabolic syndrome;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);LDL cholesterol;Response to Vitamin E supplementation;High light scatter reticulocyte count;Cholesterol, total;Coronary artery disease or large artery stroke;Mean platelet volume;Triglyceride levels;High light scatter reticulocyte percentage of red cells;Reticulocyte count;Very low density lipoprotein cholesterol levels;Hypertriglyceridemia;Metabolite levels (lipoprotein measures);Triglycerides;Coronary artery disease;HDL cholesterol;Blood metabolite levels;Vitamin E levels;LDL cholesterol levels;Circulating phylloquinone levels;Very long-chain saturated fatty acid levels (fatty acid 20:0);Postprandial triglyceride response to high fat diet meal;Coronary heart disease;Metabolite levels;Reticulocyte fraction of red cells;Red cell distribution width;Platelet distribution width;Lipoprotein-associated phospholipase A2 activity and mass;Mean corpuscular hemoglobin concentration;Total cholesterol levels;Phospholipid levels (plasma);Age-related diseases, mortality and associated endophenotypes; TGCT cis rs453301 0.606 rs6981060 chr8:8908235 C/A cg15556689 chr8:8085844 FLJ10661 -0.68 -5.58 -0.45 1.44e-7 Joint mobility (Beighton score); TGCT cis rs3829109 0.564 rs12378717 chr9:139286060 G/C cg13741927 chr9:139327495 INPP5E -0.23 -4.97 -0.41 2.14e-6 Peak insulin response;Acute insulin response; TGCT cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg03264133 chr6:25882463 NA 0.6 6.49 0.5 1.89e-9 Blood metabolite levels; TGCT cis rs2486288 0.656 rs1719236 chr15:45577783 G/T cg26924012 chr15:45694286 SPATA5L1 -0.83 -8.77 -0.62 1.16e-14 Glomerular filtration rate; TGCT cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.830 rs6832209 chr4:98994120 A/G cg17366294 chr4:99064904 C4orf37 0.68 6.96 0.53 1.75e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs881375 0.967 rs1860823 chr9:123659304 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.47 5.2 0.42 8.09e-7 Rheumatoid arthritis; TGCT cis rs10744422 0.764 rs3852535 chr12:123293656 G/A cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs9905704 0.647 rs11659035 chr17:56966052 C/T cg12560992 chr17:57184187 TRIM37 0.58 4.93 0.4 2.57e-6 Testicular germ cell tumor; TGCT cis rs2455799 0.613 rs7614204 chr3:15792748 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs146201400 1 rs146201400 chr1:26645955 G/GA cg12733254 chr1:26682999 NA -0.21 -4.58 -0.38 1.12e-5 Monocyte percentage of white cells; TGCT cis rs6879260 1.000 rs1035411 chr5:179729519 A/G cg23221052 chr5:179740743 GFPT2 -0.36 -5.76 -0.46 6.13e-8 Height; TGCT cis rs6088580 0.584 rs2378203 chr20:32993846 A/T cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 2.03e-7 Glomerular filtration rate (creatinine); TGCT cis rs6570726 0.791 rs422099 chr6:145806936 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.83 0.66 3.33e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs66561647 0.661 rs890442 chr8:128931207 G/T cg11792826 chr8:129160931 MIR1208 0.22 5.05 0.41 1.53e-6 Hemoglobin concentration; TGCT cis rs2797160 0.837 rs1739364 chr6:126022383 A/G cg05901451 chr6:126070800 HEY2 -0.69 -6.06 -0.48 1.51e-8 Endometrial cancer; TGCT cis rs832540 0.898 rs331498 chr5:56249842 C/G cg24531977 chr5:56204891 C5orf35 0.53 5.42 0.44 3e-7 Coronary artery disease; TGCT cis rs929596 0.755 rs4148324 chr2:234672722 T/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.33 -5.42 -0.44 2.95e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs2153535 0.601 rs2143353 chr6:8530111 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs13082711 0.522 rs11927257 chr3:27334294 C/T cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2115630 0.936 rs6496318 chr15:85215229 C/T cg17173187 chr15:85201210 NMB -0.41 -5.2 -0.42 7.89e-7 P wave terminal force; TGCT cis rs9549367 0.712 rs2316443 chr13:113864837 G/A cg00898013 chr13:113819073 PROZ -0.43 -5.42 -0.44 2.94e-7 Platelet distribution width; TGCT cis rs12188164 0.686 rs56279338 chr5:416118 G/A cg22025206 chr5:502436 SLC9A3 -0.26 -4.69 -0.39 7.2e-6 Cystic fibrosis severity; TGCT cis rs10186029 0.676 rs4673721 chr2:213941643 T/G cg08319019 chr2:214017104 IKZF2 0.63 5.81 0.46 5.05e-8 Systemic sclerosis; TGCT cis rs12019136 1 rs12019136 chr19:5835677 G/A cg25387410 chr19:5844109 FUT3 -0.54 -6.45 -0.5 2.27e-9 Advanced age-related macular degeneration;IgG N-glycosylation phenotypes (multivariate analysis); TGCT cis rs4824093 0.610 rs4141437 chr22:50243719 C/G cg20569369 chr22:51173646 NA -0.27 -4.57 -0.38 1.18e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2277425 0.755 rs2277424 chr13:111522420 A/G cg16032841 chr13:111522222 C13orf29 -0.52 -7.11 -0.54 8.27e-11 Sitting height ratio; TGCT cis rs2228479 0.557 rs12933317 chr16:89828220 A/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs11118844 0.793 rs11118854 chr1:221943678 T/C cg04222084 chr1:221915650 DUSP10 -0.8 -5.55 -0.45 1.62e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs8133974 0.878 rs56045941 chr21:36421331 T/C cg06758350 chr21:36259460 RUNX1 -0.4 -4.48 -0.37 1.67e-5 Eosinophil counts;Eosinophil percentage of granulocytes;Sum eosinophil basophil counts; TGCT cis rs2153535 0.580 rs7753192 chr6:8482637 G/A cg07606381 chr6:8435919 SLC35B3 0.53 4.89 0.4 3.08e-6 Motion sickness; TGCT cis rs7260538 0.509 rs10420194 chr19:41529781 A/T cg20630647 chr19:41531805 NA 0.39 6.2 0.49 7.68e-9 DDT metabolite (p,p'-DDE levels); TGCT cis rs769267 0.930 rs10402451 chr19:19608537 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs12478296 1.000 rs6732595 chr2:243035338 T/C cg06360820 chr2:242988706 NA -0.59 -4.61 -0.38 9.95e-6 Obesity-related traits; TGCT cis rs539096 0.915 rs2842194 chr1:44028962 G/A cg12908607 chr1:44402522 ARTN 0.49 5.13 0.42 1.07e-6 Intelligence (multi-trait analysis); TGCT cis rs1692580 0.870 rs262680 chr1:2167149 C/T cg21194808 chr1:2205498 SKI 0.31 5.95 0.47 2.55e-8 Coronary artery disease; TGCT cis rs7666738 0.830 rs13102369 chr4:99045912 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs79387448 0.638 rs6741230 chr2:103069631 C/T cg09003973 chr2:102972529 NA 1.28 9.8 0.66 3.95e-17 Gut microbiota (bacterial taxa); TGCT trans rs208520 0.661 rs207079 chr6:66770462 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -11.24 -0.71 1.23e-20 Exhaled nitric oxide output; TGCT cis rs2075671 0.903 rs11979818 chr7:100293639 A/G cg20848291 chr7:100343083 ZAN 0.54 4.58 0.38 1.12e-5 Other erythrocyte phenotypes; TGCT cis rs35306767 0.855 rs61830932 chr10:934183 T/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs2013441 1.000 rs17759923 chr17:20022035 G/A cg18979559 chr17:20280153 CCDC144C 0.47 4.9 0.4 2.96e-6 Obesity-related traits; TGCT cis rs3935685 0.874 rs4076998 chr15:78025420 T/G cg03457338 chr15:78040120 NA -0.22 -5.85 -0.46 4.17e-8 Intelligence (multi-trait analysis); TGCT cis rs1568889 1.000 rs34140872 chr11:28335872 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.75 0.62 1.27e-14 Bipolar disorder; TGCT cis rs9638182 0.830 rs34346326 chr7:73016181 T/C cg14087351 chr7:73037990 MLXIPL -0.54 -4.5 -0.37 1.55e-5 Triglycerides; TGCT cis rs10875746 0.680 rs4760610 chr12:48418225 C/T cg20731937 chr12:48336164 NA 0.72 6.1 0.48 1.23e-8 Longevity (90 years and older); TGCT cis rs739496 0.579 rs7294902 chr12:112354531 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.42 0.44 2.97e-7 Platelet count; TGCT cis rs6669384 0.723 rs4844395 chr1:208037967 A/G cg22525895 chr1:207977042 MIR29B2 0.4 5.28 0.43 5.67e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs6088590 1.000 rs6120750 chr20:33465289 A/C cg24642439 chr20:33292090 TP53INP2 0.7 5.98 0.47 2.17e-8 Coronary artery disease; TGCT cis rs9914544 0.524 rs7209853 chr17:18798600 G/A cg26378065 chr17:18585709 ZNF286B 0.51 4.59 0.38 1.09e-5 Educational attainment (years of education); TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs11585357 0.689 rs2977293 chr1:17599444 C/T cg08277548 chr1:17600880 PADI3 -0.67 -6.67 -0.51 7.75e-10 Hair shape; TGCT cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg17554472 chr22:41940697 POLR3H -0.42 -4.56 -0.38 1.19e-5 Vitiligo; TGCT cis rs9527 0.590 rs7074395 chr10:104844928 A/C cg04362960 chr10:104952993 NT5C2 -0.65 -5.59 -0.45 1.36e-7 Arsenic metabolism; TGCT cis rs6088580 0.584 rs2378203 chr20:32993846 A/T cg06115741 chr20:33292138 TP53INP2 -0.53 -4.63 -0.38 8.94e-6 Glomerular filtration rate (creatinine); TGCT cis rs1541995 0.824 rs1822246 chr15:96245020 A/G cg00882281 chr15:96346592 NA 0.29 4.83 0.4 3.88e-6 Photic sneeze reflex; TGCT cis rs1158570 0.500 rs2791342 chr8:131314429 C/T cg16277922 chr8:131349729 ASAP1 -0.4 -5.11 -0.42 1.2e-6 Platelet count; TGCT cis rs9926296 0.546 rs6500442 chr16:89828862 T/C cg21285383 chr16:89894308 SPIRE2 0.44 6.91 0.53 2.24e-10 Vitiligo; TGCT cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2115630 1.000 rs10220733 chr15:85280864 G/A cg17173187 chr15:85201210 NMB -0.39 -4.76 -0.39 5.4e-6 P wave terminal force; TGCT cis rs9916302 0.904 rs8079303 chr17:37530755 G/C cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs9787249 0.957 rs12239844 chr1:40217258 T/C cg19912559 chr1:40204330 PPIE 0.49 5.68 0.45 9.03e-8 Blood protein levels; TGCT cis rs2050392 0.965 rs1543725 chr10:30698873 A/G cg13289132 chr10:30722225 MAP3K8 -0.4 -5.1 -0.42 1.22e-6 Inflammatory bowel disease; TGCT cis rs4455778 0.659 rs10264682 chr7:49038952 C/T cg26309511 chr7:48887640 NA 0.44 5.13 0.42 1.07e-6 Lung cancer in never smokers; TGCT cis rs2798269 0.604 rs2488803 chr13:22159277 A/G cg18095732 chr13:22033692 ZDHHC20 -0.5 -4.45 -0.37 1.88e-5 PR segment; TGCT cis rs10504229 0.680 rs11777459 chr8:58044241 A/T cg08280861 chr8:58055591 NA 0.39 5.44 0.44 2.74e-7 Developmental language disorder (linguistic errors); TGCT cis rs7681440 0.904 rs28415623 chr4:90767110 C/T cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs208520 0.690 rs1776365 chr6:66834474 G/T cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs6089829 1.000 rs6089828 chr20:61668998 C/T cg02380750 chr20:61661411 NA 0.37 6.64 0.51 8.85e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs981844 0.683 rs1037653 chr4:154749992 A/T cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs6558530 0.653 rs6984632 chr8:1700434 G/A cg09410841 chr8:1729607 CLN8 0.72 6.44 0.5 2.41e-9 Systolic blood pressure; TGCT cis rs7312933 0.584 rs7974654 chr12:42630466 C/A cg19980929 chr12:42632907 YAF2 0.41 5.86 0.47 3.85e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs1670533 1.000 rs6827357 chr4:1059202 A/C cg20887711 chr4:1340912 KIAA1530 0.67 5.17 0.42 9.27e-7 Recombination rate (females); TGCT cis rs2075371 1.000 rs2598291 chr7:133988313 C/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.36e-9 Mean platelet volume; TGCT cis rs35306767 0.903 rs12763396 chr10:927357 C/A cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs28595532 0.623 rs34958556 chr4:119222074 C/T cg21605333 chr4:119757512 SEC24D 0.75 4.58 0.38 1.1e-5 Cannabis dependence symptom count; TGCT cis rs7100689 0.646 rs4468295 chr10:82119276 C/G cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs244731 0.920 rs244707 chr5:176555636 A/T cg17509989 chr5:176798049 RGS14 0.59 6.73 0.52 5.55e-10 Urate levels in lean individuals; TGCT cis rs74181299 0.571 rs2302647 chr2:65283174 G/A cg05010058 chr2:65284262 CEP68 0.49 5.01 0.41 1.79e-6 Pulse pressure; TGCT cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg14983838 chr19:29218262 NA 0.86 7.07 0.54 9.71e-11 Methadone dose in opioid dependence; TGCT cis rs3008870 0.959 rs4655658 chr1:67389608 C/T cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs2692947 0.673 rs2917662 chr2:96794957 G/A cg05933789 chr2:97190408 NA 0.16 4.64 0.38 8.81e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7172971 0.655 rs7170413 chr15:42344505 C/T cg05886115 chr15:42349113 NA 0.31 4.88 0.4 3.21e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs11096990 0.634 rs17754 chr4:39289308 G/C cg20847110 chr4:39482781 LOC401127 0.16 4.51 0.38 1.48e-5 Cognitive function; TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.12 0.54 7.79e-11 Prudent dietary pattern; TGCT cis rs60154123 0.686 rs227222 chr1:210191272 T/C cg22029157 chr1:209979665 IRF6 -0.73 -4.58 -0.38 1.11e-5 Coronary artery disease; TGCT cis rs2204008 0.658 rs11181310 chr12:38315963 C/A cg13010199 chr12:38710504 ALG10B 0.59 4.59 0.38 1.07e-5 Bladder cancer; TGCT cis rs7917772 0.582 rs10786696 chr10:104378134 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs910316 1.000 rs10873275 chr14:75531460 A/T cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs28735056 0.596 rs3744879 chr18:77679006 G/C cg20368463 chr18:77673604 PQLC1 -0.53 -6.45 -0.5 2.27e-9 Schizophrenia; TGCT trans rs2688608 0.967 rs1815076 chr10:75659886 C/T cg13918328 chr10:52500089 ASAH2B 0.64 6.65 0.51 8.42e-10 Inflammatory bowel disease; TGCT trans rs7618501 1.000 rs695238 chr3:49869158 A/C cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs868036 0.681 rs4776977 chr15:68108219 C/T cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs1801251 1.000 rs6745879 chr2:233590007 A/G cg25237894 chr2:233734115 C2orf82 0.32 5.81 0.46 4.94e-8 Coronary artery disease; TGCT cis rs295140 0.903 rs7605146 chr2:201183888 A/G cg04283868 chr2:201171347 SPATS2L -0.62 -6.26 -0.49 5.69e-9 QT interval; TGCT cis rs9807989 0.507 rs6726985 chr2:103048580 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs79149102 0.579 rs74023936 chr15:75362084 C/T cg09165964 chr15:75287851 SCAMP5 -1.04 -5.78 -0.46 5.77e-8 Lung cancer; TGCT cis rs3849570 0.925 rs1464791 chr3:81893929 A/C cg07356753 chr3:81810745 GBE1 0.74 6.77 0.52 4.57e-10 Waist circumference;Body mass index; TGCT cis rs2046867 0.819 rs34132129 chr3:72829100 A/G cg25664220 chr3:72788482 NA -0.56 -6.89 -0.53 2.49e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs12893668 0.697 rs67899457 chr14:104060066 A/T cg26031613 chr14:104095156 KLC1 -0.55 -4.61 -0.38 9.69e-6 Reticulocyte count; TGCT cis rs56114371 0.530 rs2056923 chr6:27689939 T/C cg20933634 chr6:27740509 NA 0.42 4.78 0.39 4.81e-6 Breast cancer; TGCT trans rs3780486 0.718 rs7859454 chr9:33119583 T/A cg04842962 chr6:43655489 MRPS18A 1.0 7.22 0.54 4.61e-11 IgG glycosylation; TGCT cis rs4824093 0.610 rs73441745 chr22:50237606 G/A cg14114931 chr22:50943910 LMF2 0.36 4.57 0.38 1.14e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs36051895 0.659 rs62541539 chr9:5038180 C/T cg02405213 chr9:5042618 JAK2 -0.78 -10.74 -0.69 2.01e-19 Pediatric autoimmune diseases; TGCT cis rs1577917 1.000 rs1995688 chr6:86632319 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs13118159 0.801 rs1128427 chr4:1330759 T/C cg13395646 chr4:1353034 KIAA1530 -0.41 -4.6 -0.38 1.01e-5 Longevity; TGCT cis rs9653442 0.564 rs4850924 chr2:100782273 A/G cg22139774 chr2:100720529 AFF3 -0.35 -5.44 -0.44 2.79e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs778371 0.578 rs2675956 chr2:233753340 G/A cg08000102 chr2:233561755 GIGYF2 -0.48 -4.83 -0.4 3.92e-6 Schizophrenia; TGCT cis rs3091242 0.900 rs35345536 chr1:25766488 A/G cg00786635 chr1:25594202 NA 0.55 5.74 0.46 6.71e-8 Erythrocyte sedimentation rate; TGCT cis rs9911578 0.967 rs2333410 chr17:57137129 G/A cg12560992 chr17:57184187 TRIM37 -0.79 -9.71 -0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs2239547 0.607 rs9836178 chr3:52925403 T/C cg10802521 chr3:52805072 NEK4 0.63 5.67 0.45 9.48e-8 Schizophrenia; TGCT cis rs4773860 0.512 rs2892715 chr13:95894329 A/G cg22859289 chr13:95358476 NA 0.26 4.53 0.38 1.38e-5 Plateletcrit; TGCT cis rs4478858 0.684 rs7544946 chr1:31749736 T/C cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs2072499 0.931 rs1052053 chr1:156202173 A/G cg24450063 chr1:156163899 SLC25A44 1.02 12.94 0.76 9.07e-25 Testicular germ cell tumor; TGCT trans rs2727020 0.521 rs7946190 chr11:49521964 T/A cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Coronary artery disease; TGCT cis rs751728 1.000 rs4713682 chr6:33757047 G/C cg13859433 chr6:33739653 LEMD2 -0.39 -7.13 -0.54 7.23e-11 Crohn's disease; TGCT trans rs7618501 1.000 rs3811696 chr3:49761605 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs1670533 0.872 rs935969 chr4:1062588 A/G cg20887711 chr4:1340912 KIAA1530 0.65 5.11 0.42 1.16e-6 Recombination rate (females); TGCT cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9868809 0.881 rs2286652 chr3:48689192 G/A cg00383909 chr3:49044727 WDR6 1.11 5.97 0.47 2.28e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs2404602 0.647 rs3812908 chr15:77176158 C/T cg23625390 chr15:77176239 SCAPER 0.39 5.04 0.41 1.6e-6 Blood metabolite levels; TGCT cis rs854765 0.547 rs4072739 chr17:17884660 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.29 0.55 3.14e-11 Total body bone mineral density; TGCT cis rs9926296 0.605 rs886951 chr16:89836865 A/G cg04287289 chr16:89883240 FANCA 0.91 11.74 0.73 7.21e-22 Vitiligo; TGCT cis rs9611565 0.546 rs34077262 chr22:42061639 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.87 0.4 3.34e-6 Vitiligo; TGCT cis rs2153535 0.580 rs1889715 chr6:8443475 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs4722166 0.630 rs10950916 chr7:22799667 C/T cg13104385 chr7:22767384 IL6 0.2 4.59 0.38 1.08e-5 Lung cancer; TGCT trans rs11218343 1.000 rs2276412 chr11:121460846 C/T cg21762680 chr3:195295723 APOD 0.68 6.63 0.51 9.32e-10 Alzheimer's disease in APOE e4- carriers;Alzheimer's disease (late onset); TGCT cis rs11190604 0.767 rs35508946 chr10:102191156 A/G cg16005271 chr10:102321736 NA 0.45 4.7 0.39 6.81e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg18538332 chr22:24372958 LOC391322 0.84 9.55 0.65 1.54e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7772486 0.686 rs1415744 chr6:146022531 C/T cg23711669 chr6:146136114 FBXO30 0.85 9.73 0.66 5.58e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7089973 0.584 rs758585 chr10:116582560 C/A cg03647239 chr10:116582469 FAM160B1 0.6 5.75 0.46 6.7e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs10465746 0.653 rs11163877 chr1:84441848 T/A cg10977910 chr1:84465055 TTLL7 0.69 7.1 0.54 8.59e-11 Obesity-related traits; TGCT cis rs67478160 0.529 rs12880413 chr14:104267407 A/G cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs4803468 1.000 rs11883104 chr19:41923799 T/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.72 -0.69 2.21e-19 Height; TGCT cis rs7662987 0.517 rs2602878 chr4:100039953 T/G cg12011299 chr4:100065546 ADH4 0.41 4.91 0.4 2.81e-6 Smoking initiation; TGCT cis rs10779751 1.000 rs1010447 chr1:11269796 A/G cg08854313 chr1:11322531 MTOR 1.0 10.26 0.68 2.99e-18 Body mass index; TGCT cis rs2050392 0.792 rs303434 chr10:30714440 G/A cg13289132 chr10:30722225 MAP3K8 -0.39 -4.68 -0.39 7.52e-6 Inflammatory bowel disease; TGCT cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg23156509 chr2:114033830 PAX8;LOC440839 -0.3 -4.45 -0.37 1.88e-5 Lymphocyte counts; TGCT cis rs2594989 1.000 rs2606740 chr3:11392441 G/A cg00170343 chr3:11313890 ATG7 0.66 4.68 0.39 7.32e-6 Circulating chemerin levels; TGCT trans rs2727020 0.514 rs4980444 chr11:49550764 T/A cg03929089 chr4:120376271 NA -0.66 -7.6 -0.56 6.24e-12 Coronary artery disease; TGCT cis rs2760061 0.626 rs2527614 chr1:228126470 A/G cg02753203 chr1:228287806 NA -0.34 -6.56 -0.51 1.31e-9 Diastolic blood pressure; TGCT cis rs6089829 0.888 rs4809268 chr20:61675249 C/G cg08564027 chr20:61660810 NA 0.37 5.98 0.47 2.26e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs9296661 0.522 rs10948647 chr6:51664212 T/A cg20180370 chr6:50691003 TFAP2D 0.48 4.58 0.38 1.1e-5 Weight loss (gastric bypass surgery); TGCT cis rs7833790 0.660 rs10091077 chr8:82705464 A/G cg17211192 chr8:82754475 SNX16 -0.89 -7.96 -0.58 9.36e-13 Diastolic blood pressure; TGCT cis rs909674 0.909 rs1557541 chr22:39851970 C/A cg05872129 chr22:39784769 NA -0.98 -9.6 -0.65 1.19e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs797680 0.861 rs612037 chr1:93682878 G/A cg17826107 chr1:92977322 EVI5 0.24 5.3 0.43 5.16e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg02725872 chr8:58115012 NA -0.39 -4.8 -0.4 4.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs6598955 0.671 rs12089149 chr1:26638500 C/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs8179 1.000 rs42031 chr7:92237396 A/T cg15732164 chr7:92237376 CDK6 -0.33 -4.87 -0.4 3.3e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs9811920 0.638 rs704581 chr3:99556160 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 7.02 0.53 1.32e-10 Axial length; TGCT cis rs7599312 0.534 rs7607373 chr2:213409719 G/A cg16329650 chr2:213403929 ERBB4 1.07 16.1 0.82 3.58e-32 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7647973 0.925 rs9834003 chr3:49216472 T/C cg07636037 chr3:49044803 WDR6 0.63 5.09 0.42 1.27e-6 Menarche (age at onset); TGCT cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs909002 0.772 rs10798876 chr1:32074514 C/G cg11573219 chr1:32083031 HCRTR1 -0.45 -5.87 -0.47 3.67e-8 Intelligence (multi-trait analysis); TGCT cis rs12681287 0.752 rs13262673 chr8:87293600 G/A cg27223183 chr8:87520930 FAM82B -0.82 -5.86 -0.47 3.98e-8 Caudate activity during reward; TGCT cis rs9611565 0.568 rs5758441 chr22:42132888 C/A cg17554472 chr22:41940697 POLR3H 0.43 4.54 0.38 1.31e-5 Vitiligo; TGCT cis rs8141529 0.732 rs5762788 chr22:29174770 G/T cg02153584 chr22:29168773 CCDC117 0.63 5.38 0.43 3.58e-7 Lymphocyte counts; TGCT cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg09177884 chr7:1199841 ZFAND2A -0.5 -4.87 -0.4 3.35e-6 Longevity;Endometriosis; TGCT cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg19774624 chr17:42201019 HDAC5 0.81 9.74 0.66 5.37e-17 Total body bone mineral density; TGCT cis rs2019216 0.500 rs7502283 chr17:21878561 G/C cg22648282 chr17:21454238 C17orf51 -0.57 -5.13 -0.42 1.08e-6 Pelvic organ prolapse; TGCT cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg23758822 chr17:41437982 NA 0.77 7.21 0.54 4.92e-11 Menopause (age at onset); TGCT cis rs9303401 0.659 rs35539277 chr17:56853833 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs4253772 0.591 rs6007748 chr22:46657798 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.55 4.46 0.37 1.84e-5 LDL cholesterol;Cholesterol, total; TGCT trans rs1005277 0.579 rs1780121 chr10:38529437 C/A cg27523141 chr10:43048294 ZNF37B 0.73 8.5 0.61 5.09e-14 Extrinsic epigenetic age acceleration; TGCT trans rs1814175 0.935 rs7925863 chr11:49615802 C/A cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs4711350 0.734 rs9380379 chr6:33766131 A/G cg13859433 chr6:33739653 LEMD2 -0.31 -4.64 -0.38 8.54e-6 Schizophrenia; TGCT cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.66 6.13 0.48 1.06e-8 Height; TGCT cis rs617219 0.726 rs2364596 chr5:78434291 C/T cg05890484 chr5:78407552 BHMT 0.4 5.53 0.44 1.85e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9467773 1.000 rs6925703 chr6:26521589 G/A cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9457247 1.000 rs385863 chr6:167386615 C/G cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs7246657 0.722 rs2075284 chr19:38189616 T/C cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs10882165 0.779 rs57708198 chr10:94910526 G/T cg15980076 chr10:94822747 CYP26C1 0.44 4.77 0.39 5.13e-6 Refractive error; TGCT cis rs3820068 0.822 rs2901964 chr1:15792426 C/G cg05660106 chr1:15850417 CASP9 0.88 7.92 0.58 1.13e-12 Systolic blood pressure; TGCT cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg17179660 chr6:151773299 C6orf211;RMND1 0.59 5.43 0.44 2.84e-7 Menarche (age at onset); TGCT cis rs6430585 0.528 rs75753154 chr2:136665711 T/C cg07169764 chr2:136633963 MCM6 1.25 12.45 0.75 1.36e-23 Corneal structure; TGCT cis rs8013055 0.898 rs8004007 chr14:105971435 G/C cg19700328 chr14:106028568 NA -0.53 -5.87 -0.47 3.76e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs17076896 0.748 rs7325676 chr13:19933749 T/G cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs7208859 0.673 rs11657270 chr17:29214387 A/G cg14008862 chr17:28927542 LRRC37B2 0.71 4.71 0.39 6.63e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4665809 1.000 rs6546744 chr2:26302161 A/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs10779751 1.000 rs4845859 chr1:11304873 A/G cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs7246657 0.722 rs2287229 chr19:38188652 G/A cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs17253792 0.822 rs113350960 chr14:56087713 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs12220898 0.749 rs3996894 chr10:50484369 G/A cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg10207240 chr12:122356781 WDR66 0.34 4.68 0.39 7.53e-6 Mean corpuscular volume; TGCT cis rs2663905 0.706 rs2683260 chr15:81385552 A/C cg09236163 chr15:81426669 C15orf26 -0.6 -5.71 -0.46 7.81e-8 QT interval (drug interaction); TGCT trans rs941408 1.000 rs1736176 chr19:2790394 G/A cg22153745 chr1:153894579 GATAD2B -0.61 -6.84 -0.52 3.28e-10 Total cholesterol levels; TGCT cis rs2153535 0.580 rs6900007 chr6:8474035 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs514406 0.830 rs533935 chr1:53308807 T/C cg25767906 chr1:53392781 SCP2 -0.55 -6.25 -0.49 5.98e-9 Monocyte count; TGCT cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg00684032 chr4:1343700 KIAA1530 0.23 4.9 0.4 2.87e-6 Obesity-related traits; TGCT cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs6964587 1.000 rs2157747 chr7:91750578 A/G cg17063962 chr7:91808500 NA 0.87 9.26 0.64 7.82e-16 Breast cancer; TGCT cis rs13191362 1.000 rs13210412 chr6:163019478 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1215050 0.755 rs7696354 chr4:98820330 T/C cg17366294 chr4:99064904 C4orf37 0.56 6.06 0.48 1.53e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs597539 0.580 rs7935851 chr11:68731122 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 7.17 0.54 5.86e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg18278486 chr6:26987575 LOC100270746;C6orf41 0.37 4.46 0.37 1.81e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs611744 0.810 rs619227 chr8:109215100 C/A cg21045802 chr8:109455806 TTC35 0.7 6.26 0.49 5.73e-9 Dupuytren's disease; TGCT cis rs7786808 0.741 rs7789415 chr7:158227617 C/T cg01191920 chr7:158217561 PTPRN2 -0.42 -6.29 -0.49 4.94e-9 Obesity-related traits; TGCT cis rs2576037 0.583 rs644731 chr18:44426877 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs7666738 0.791 rs60028147 chr4:99046618 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg07061783 chr6:25882402 NA -0.56 -5.34 -0.43 4.28e-7 Intelligence (multi-trait analysis); TGCT cis rs524023 1.000 rs9734313 chr11:64358311 C/T cg07733098 chr11:64478343 NRXN2 0.31 4.63 0.38 8.93e-6 Urate levels in obese individuals; TGCT trans rs13064411 0.542 rs9877649 chr3:113226874 C/T cg00307254 chr3:126706825 PLXNA1 0.34 6.78 0.52 4.36e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs992157 0.672 rs2382829 chr2:219184617 G/A cg00012203 chr2:219082015 ARPC2 0.7 6.58 0.51 1.16e-9 Colorectal cancer; TGCT cis rs10892173 0.846 rs2298647 chr11:117671641 A/T cg07621104 chr11:117668040 DSCAML1 0.48 5.02 0.41 1.78e-6 Myopia; TGCT cis rs611744 0.563 rs7815105 chr8:109298794 C/T cg21045802 chr8:109455806 TTC35 0.7 6.96 0.53 1.76e-10 Dupuytren's disease; TGCT cis rs7843479 1.000 rs10503715 chr8:21850687 G/A cg17168535 chr8:21777572 XPO7 0.63 5.76 0.46 6.15e-8 Mean corpuscular volume; TGCT cis rs977747 1.000 rs2984618 chr1:47690438 G/T cg03885399 chr1:47691550 TAL1 0.37 4.44 0.37 1.95e-5 Body mass index; TGCT cis rs60871478 0.787 rs4720928 chr7:808002 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.6 0.38 1.04e-5 Cerebrospinal P-tau181p levels; TGCT cis rs28735056 0.967 rs8091497 chr18:77632565 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs28595532 0.748 rs115651241 chr4:119363509 C/T cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg06212747 chr3:49208901 KLHDC8B 0.67 6.36 0.5 3.57e-9 Menarche (age at onset); TGCT cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs2836974 0.666 rs11910705 chr21:40685604 C/T cg11644478 chr21:40555479 PSMG1 -0.6 -5.37 -0.43 3.72e-7 Cognitive function; TGCT cis rs4523957 0.614 rs7219693 chr17:2061101 C/A cg16513277 chr17:2031491 SMG6 -0.2 -4.61 -0.38 9.88e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9549367 0.789 rs2287244 chr13:113887173 C/G cg00898013 chr13:113819073 PROZ 0.4 4.95 0.41 2.4e-6 Platelet distribution width; TGCT cis rs9443645 0.901 rs9448596 chr6:79629429 T/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs6921964 chr6:8446395 A/G cg07606381 chr6:8435919 SLC35B3 0.55 5.17 0.42 9.24e-7 Motion sickness; TGCT cis rs250677 0.522 rs56309414 chr5:148376026 C/G cg18129178 chr5:148520854 ABLIM3 -0.36 -4.69 -0.39 7.23e-6 Breast cancer; TGCT cis rs12477438 1.000 rs11897712 chr2:99735697 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.77 -5.89 -0.47 3.32e-8 Chronic sinus infection; TGCT cis rs7193541 0.662 rs8052367 chr16:74658867 G/A cg01733217 chr16:74700730 RFWD3 1.01 13.89 0.78 4.94e-27 Multiple myeloma; TGCT cis rs362272 0.524 rs881816 chr4:3365366 A/G cg18352616 chr4:3374830 RGS12 0.23 4.54 0.38 1.31e-5 Serum sulfate level; TGCT cis rs4927850 0.958 rs1975582 chr3:195751439 G/T cg22891161 chr3:195456627 MUC20 -0.23 -5.38 -0.44 3.53e-7 Pancreatic cancer; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg25151919 chr3:44754333 ZNF502 -0.4 -4.59 -0.38 1.06e-5 Depressive symptoms; TGCT cis rs7179456 0.545 rs2250583 chr15:59050382 C/T cg05156742 chr15:59063176 FAM63B -0.51 -4.89 -0.4 3.05e-6 Asperger disorder; TGCT cis rs6840360 0.571 rs11729136 chr4:152529227 C/A cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs1982963 1.000 rs753050 chr14:52505375 A/G cg10843707 chr14:52510701 NID2 -0.43 -6.6 -0.51 1.09e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2404602 1.000 rs6495206 chr15:76870963 C/T cg26408565 chr15:76604113 ETFA -0.38 -4.88 -0.4 3.24e-6 Blood metabolite levels; TGCT cis rs12478296 0.892 rs11897561 chr2:243014976 C/A cg06360820 chr2:242988706 NA -0.59 -4.83 -0.4 3.89e-6 Obesity-related traits; TGCT trans rs10504390 0.656 rs17302765 chr8:66474459 A/G cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.26e-10 IgG glycosylation; TGCT cis rs2120019 1.000 rs35736167 chr15:75332002 T/G cg11632617 chr15:75315747 PPCDC -0.3 -4.47 -0.37 1.71e-5 Blood trace element (Zn levels); TGCT cis rs9549260 0.753 rs9549238 chr13:41179321 G/A cg21288729 chr13:41239152 FOXO1 0.67 4.68 0.39 7.31e-6 Red blood cell count; TGCT cis rs595982 0.559 rs17206700 chr19:49361255 A/G cg15549821 chr19:49342101 PLEKHA4 -0.68 -9.12 -0.63 1.67e-15 Red cell distribution width; TGCT cis rs7607369 0.617 rs12987009 chr2:219658170 A/T cg02176678 chr2:219576539 TTLL4 -0.48 -6.16 -0.48 9.24e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs459571 0.959 rs465535 chr9:136910905 C/T cg14405625 chr9:136855902 VAV2 -0.3 -4.54 -0.38 1.3e-5 Platelet distribution width; TGCT cis rs7208859 0.573 rs73277960 chr17:29177441 T/C cg18442181 chr17:29233375 C17orf42 -0.79 -4.71 -0.39 6.66e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2458413 0.935 rs2514667 chr8:105358590 C/T cg04554929 chr8:105342491 NA 0.55 7.92 0.58 1.18e-12 Paget's disease; TGCT cis rs1153858 1.000 rs16952714 chr15:45650358 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs9818758 0.607 rs9837237 chr3:49215583 G/T cg07636037 chr3:49044803 WDR6 -1.04 -5.15 -0.42 1.01e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7568458 0.837 rs12714145 chr2:85787341 C/T cg17127132 chr2:85788382 GGCX 0.67 6.08 0.48 1.35e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9467773 1.000 rs9467773 chr6:26498426 A/G cg09904177 chr6:26538194 HMGN4 0.64 6.49 0.5 1.89e-9 Intelligence (multi-trait analysis); TGCT cis rs372883 0.600 rs2832294 chr21:30739671 A/C cg24692254 chr21:30365293 RNF160 0.51 4.6 0.38 1.02e-5 Pancreatic cancer; TGCT cis rs4654899 0.865 rs6664532 chr1:21515800 G/A cg01072550 chr1:21505969 NA -0.48 -7.14 -0.54 7.03e-11 Superior frontal gyrus grey matter volume; TGCT cis rs7552404 0.883 rs11161493 chr1:76206254 T/A cg22875332 chr1:76189707 ACADM 0.77 9.49 0.65 2.13e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT trans rs208520 0.802 rs208516 chr6:66946119 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.93 -0.67 1.84e-17 Exhaled nitric oxide output; TGCT cis rs3087591 1.000 rs2905791 chr17:29472888 T/C cg24425628 chr17:29625626 OMG;NF1 0.47 7.52 0.56 9.75e-12 Hip circumference; TGCT cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg11301795 chr4:187892539 NA -0.33 -5.07 -0.41 1.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11190604 0.943 rs7900678 chr10:102229016 T/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs5750830 0.594 rs5757650 chr22:39778419 A/G cg11247378 chr22:39784982 NA -0.63 -8.71 -0.62 1.64e-14 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg22920501 chr2:26401640 FAM59B 0.81 6.31 0.49 4.52e-9 Gut microbiome composition (summer); TGCT cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg07424592 chr7:64974309 NA -1.34 -8.08 -0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg01017244 chr2:74357527 NA 0.5 8.29 0.6 1.58e-13 Gestational age at birth (maternal effect); TGCT cis rs17376456 0.825 rs17372649 chr5:93126096 C/G cg25358565 chr5:93447407 FAM172A 0.9 7.65 0.57 4.86e-12 Diabetic retinopathy; TGCT cis rs11792861 0.781 rs72607159 chr9:111764270 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.69 0.39 7.21e-6 Menarche (age at onset); TGCT cis rs8054556 0.787 rs12921753 chr16:30018720 C/T cg06015834 chr16:30021696 DOC2A -0.27 -4.44 -0.37 1.94e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7582180 0.652 rs11687865 chr2:100947000 T/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs17473412 0.677 rs7737667 chr5:122875622 T/G cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs447735 0.565 rs10852626 chr16:89914633 T/G cg03388025 chr16:89894329 SPIRE2 0.35 4.92 0.4 2.72e-6 Hemoglobin concentration; TGCT trans rs9951602 0.512 rs6506872 chr18:76649695 T/C cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs7917772 0.536 rs12357172 chr10:104388549 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 7.61 0.56 5.87e-12 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8077889 0.719 rs4793033 chr17:41879627 C/T cg26893861 chr17:41843967 DUSP3 1.13 19.78 0.87 3.55e-40 Triglycerides; TGCT cis rs1215050 0.740 rs1214994 chr4:99035577 C/T cg17366294 chr4:99064904 C4orf37 0.58 6.26 0.49 5.76e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.83 -0.4 3.92e-6 Intelligence (multi-trait analysis); TGCT cis rs7412746 0.658 rs4970986 chr1:150907955 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs2463822 1.000 rs118049526 chr11:62107508 C/T cg23876832 chr11:62092739 NA -0.65 -4.56 -0.38 1.19e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs28595532 0.920 rs115294251 chr4:119772833 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs7659604 0.521 rs9993206 chr4:122686957 A/G cg19748678 chr4:122722346 EXOSC9 -0.53 -5.3 -0.43 5.11e-7 Type 2 diabetes; TGCT cis rs950169 0.800 rs4842847 chr15:84931199 G/A cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs2404602 0.647 rs11633869 chr15:77133322 G/T cg23625390 chr15:77176239 SCAPER 0.37 4.87 0.4 3.27e-6 Blood metabolite levels; TGCT cis rs2050392 0.829 rs306589 chr10:30723831 A/G cg13289132 chr10:30722225 MAP3K8 -0.4 -4.83 -0.4 4e-6 Inflammatory bowel disease; TGCT cis rs62064224 0.589 rs9910731 chr17:30784034 A/G cg18200150 chr17:30822561 MYO1D 0.43 5.46 0.44 2.52e-7 Schizophrenia; TGCT cis rs7044106 0.791 rs2416797 chr9:123480600 C/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.98 0.41 2.12e-6 Hip circumference adjusted for BMI; TGCT cis rs6089584 0.888 rs6089624 chr20:60619907 C/G cg13665807 chr20:60559372 TAF4 -0.45 -4.78 -0.39 4.89e-6 Body mass index; TGCT cis rs35306767 0.859 rs11817793 chr10:878895 C/T cg26597838 chr10:835615 NA 0.72 10.38 0.68 1.54e-18 Eosinophil percentage of granulocytes; TGCT cis rs778371 0.871 rs2675954 chr2:233750627 C/G cg08000102 chr2:233561755 GIGYF2 -0.58 -6.24 -0.49 6.27e-9 Schizophrenia; TGCT cis rs933688 1.000 rs4382199 chr5:90744228 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.31 0.6 1.43e-13 Smoking behavior; TGCT cis rs950169 0.580 rs11636189 chr15:85193554 G/A cg11189052 chr15:85197271 WDR73 0.76 6.33 0.49 4.04e-9 Schizophrenia; TGCT cis rs112591243 0.570 rs79100421 chr21:47969962 T/C cg10657630 chr21:48055338 PRMT2 1.03 4.63 0.38 9.08e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs2067615 0.560 rs1882542 chr12:107070049 A/C cg15890332 chr12:107067104 RFX4 0.29 5.81 0.46 4.97e-8 Heart rate; TGCT cis rs6121246 0.633 rs6060986 chr20:30426297 G/A cg13852791 chr20:30311386 BCL2L1 0.87 8.18 0.59 2.85e-13 Mean corpuscular hemoglobin; TGCT cis rs4242434 0.757 rs2280104 chr8:22525980 C/T cg21658235 chr8:22456391 C8orf58 0.43 4.75 0.39 5.48e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7809950 0.637 rs3801964 chr7:106836242 T/C cg23024343 chr7:107201750 COG5 -0.44 -6.03 -0.48 1.74e-8 Coronary artery disease; TGCT cis rs9457247 1.000 rs422562 chr6:167406318 A/G cg23791538 chr6:167370224 RNASET2 -0.5 -4.99 -0.41 2.01e-6 Crohn's disease; TGCT cis rs28595532 0.920 rs114639588 chr4:119736176 T/C cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs586688 1.000 rs632081 chr1:201643512 T/C cg05779441 chr1:201574716 NA 0.29 4.72 0.39 6.21e-6 Obesity-related traits; TGCT cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg13342137 chr4:2252803 MXD4 -0.17 -4.51 -0.38 1.5e-5 Obesity-related traits; TGCT cis rs3809566 0.559 rs4775605 chr15:63324048 C/G cg08198488 chr15:63333792 TPM1 -0.35 -5.35 -0.43 4.02e-7 Platelet count; TGCT cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg00814883 chr7:100076585 TSC22D4 -0.82 -8.37 -0.6 1.03e-13 Platelet count; TGCT cis rs8077577 0.895 rs62072500 chr17:18126918 A/C cg09161412 chr17:18057145 MYO15A -0.58 -4.73 -0.39 5.9e-6 Obesity-related traits; TGCT cis rs4499344 0.622 rs2903752 chr19:33049943 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.67 5.74 0.46 6.86e-8 Mean platelet volume; TGCT cis rs9467711 0.659 rs13216828 chr6:26373507 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.61 6.45 0.5 2.28e-9 Height; TGCT cis rs9911578 1.000 rs11870671 chr17:56605360 A/G cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs74054849 0.850 rs60513147 chr1:15962974 A/G cg05660106 chr1:15850417 CASP9 0.86 4.48 0.37 1.68e-5 Alcoholic chronic pancreatitis; TGCT cis rs921968 0.643 rs1516086 chr2:219431535 C/T cg02176678 chr2:219576539 TTLL4 0.38 5.66 0.45 1.01e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs35883536 0.647 rs11166485 chr1:101048805 G/C cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs2468186 0.583 rs2465403 chr8:120090827 A/G cg02248809 chr8:120845432 TAF2 0.44 4.7 0.39 6.79e-6 Osteoprotegerin levels; TGCT cis rs7572733 0.534 rs700678 chr2:198705820 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs28595532 0.920 rs116106661 chr4:119749794 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.4 -5.13 -0.42 1.09e-6 Alzheimer's disease; TGCT trans rs1864729 1.000 rs2439700 chr8:98277168 G/A cg08679828 chr8:102218111 ZNF706 -1.09 -7.6 -0.56 6.34e-12 Estradiol plasma levels (breast cancer); TGCT cis rs6690583 0.623 rs1371140 chr1:85455362 A/C cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs8032315 0.965 rs1894400 chr15:91428955 C/T cg04510874 chr15:91427884 FES 0.53 6.01 0.48 1.91e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs12142240 0.698 rs41294478 chr1:46818442 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs12142240 0.660 rs6679080 chr1:46819779 A/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs2688608 0.592 rs11000759 chr10:75493726 G/A cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs3087591 0.960 rs2952991 chr17:29526742 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 7.39 0.55 1.91e-11 Hip circumference; TGCT cis rs7772486 0.754 rs4896841 chr6:146041522 T/C cg23711669 chr6:146136114 FBXO30 -0.95 -11.14 -0.71 2.17e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs7975161 1.000 rs4964728 chr12:104649733 G/A cg25273343 chr12:104657179 TXNRD1 -0.31 -4.86 -0.4 3.45e-6 Toenail selenium levels; TGCT cis rs78487399 0.808 rs17031005 chr2:43761299 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.19 -0.42 8.39e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7100689 0.646 rs1934694 chr10:82125325 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs9549367 0.789 rs2302754 chr13:113898385 C/T cg18105134 chr13:113819100 PROZ 0.34 5.53 0.44 1.81e-7 Platelet distribution width; TGCT cis rs2594989 0.832 rs13325556 chr3:11566961 T/G cg26283222 chr3:11613257 VGLL4 0.22 4.57 0.38 1.18e-5 Circulating chemerin levels; TGCT cis rs2637266 1.000 rs2395390 chr10:78357734 C/G cg18941641 chr10:78392320 NA 0.37 4.5 0.37 1.53e-5 Pulmonary function; TGCT cis rs950169 0.580 rs11636189 chr15:85193554 G/A cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.97e-7 Schizophrenia; TGCT cis rs6840360 0.606 rs2709814 chr4:152360870 T/C cg17479576 chr4:152424074 FAM160A1 -0.57 -5.91 -0.47 3.07e-8 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.576 rs4882258 chr12:38453686 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1552244 0.882 rs13084194 chr3:10031492 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.36 -0.5 3.55e-9 Alzheimer's disease; TGCT cis rs7772486 0.658 rs4895683 chr6:146113654 T/A cg23711669 chr6:146136114 FBXO30 -0.86 -9.74 -0.66 5.4e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg22166914 chr1:53195759 ZYG11B 0.41 7.17 0.54 6.04e-11 Monocyte count; TGCT cis rs4074961 0.527 rs10908356 chr1:38038388 G/A cg17933807 chr1:38061675 GNL2 1.04 14.78 0.8 3.92e-29 Axial length; TGCT cis rs7103648 0.669 rs10437655 chr11:47391948 G/A cg20307385 chr11:47447363 PSMC3 0.95 11.08 0.71 2.98e-20 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs4252435 0.520 rs7797896 chr7:142641189 T/C cg21621906 chr7:142494914 NA -1.08 -4.53 -0.38 1.36e-5 Cancer; TGCT cis rs4972806 0.849 rs2113561 chr2:177030925 G/A cg03152288 chr2:177042942 NA 0.6 5.18 0.42 8.72e-7 IgG glycosylation; TGCT cis rs10782582 0.569 rs74090722 chr1:76197262 A/G cg03433033 chr1:76189801 ACADM -0.6 -6.61 -0.51 1e-9 Daytime sleep phenotypes; TGCT cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs875971 0.522 rs34973832 chr7:65396204 A/G cg18876405 chr7:65276391 NA 0.37 5.89 0.47 3.34e-8 Aortic root size; TGCT cis rs7666738 0.830 rs11727612 chr4:99001662 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.781 rs11040681 chr11:49981654 G/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs7264396 0.790 rs6060530 chr20:34227663 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.74 -0.39 5.75e-6 Total cholesterol levels; TGCT cis rs909674 0.541 rs5750812 chr22:39793079 G/A cg24399712 chr22:39784796 NA -1.04 -13.27 -0.77 1.44e-25 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs36051895 0.659 rs57204002 chr9:5062610 T/C cg02405213 chr9:5042618 JAK2 -0.72 -9.69 -0.66 7.17e-17 Pediatric autoimmune diseases; TGCT cis rs1552244 1.000 rs9834980 chr3:10065528 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9311474 0.607 rs2015971 chr3:52546820 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.85 0.4 3.63e-6 Electroencephalogram traits; TGCT cis rs6840360 0.642 rs10857260 chr4:152424056 C/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs769267 0.930 rs10422819 chr19:19643028 C/A cg20644253 chr19:19431407 KIAA0892;SF4 0.66 5.43 0.44 2.84e-7 Tonsillectomy; TGCT cis rs28595532 0.920 rs115154776 chr4:119774803 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg23156509 chr2:114033830 PAX8;LOC440839 -0.3 -4.56 -0.38 1.2e-5 Lymphocyte counts; TGCT cis rs6835098 1.000 rs10011724 chr4:174088865 A/G cg08422745 chr4:174089978 GALNT7 -0.95 -11.46 -0.72 3.51e-21 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs78456975 0.527 rs11884165 chr2:1561052 A/G cg01028140 chr2:1542097 TPO -0.33 -5.12 -0.42 1.14e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs4665809 0.549 rs7577896 chr2:26524493 C/T cg22920501 chr2:26401640 FAM59B 0.8 5.02 0.41 1.78e-6 Gut microbiome composition (summer); TGCT cis rs17376456 0.877 rs12153506 chr5:93360953 T/G cg21475434 chr5:93447410 FAM172A 0.6 4.73 0.39 6.08e-6 Diabetic retinopathy; TGCT cis rs56104184 0.887 rs4801778 chr19:49370609 G/T cg15549821 chr19:49342101 PLEKHA4 -0.64 -8.96 -0.63 4.09e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs11190604 1.000 rs2489049 chr10:102350732 G/A cg16342193 chr10:102329863 NA -0.4 -5.12 -0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2486288 0.656 rs9921025 chr15:45546602 G/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs6993813 0.589 rs4397431 chr8:120018413 G/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs6940638 0.606 rs6456771 chr6:27232395 G/A cg05738196 chr6:26577821 NA -0.55 -4.48 -0.37 1.7e-5 Intelligence (multi-trait analysis); TGCT trans rs7824557 0.564 rs2736304 chr8:11236964 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.69 -0.51 6.84e-10 Retinal vascular caliber; TGCT cis rs10779751 0.960 rs4845988 chr1:11319587 A/G cg08854313 chr1:11322531 MTOR 0.93 10.22 0.68 3.75e-18 Body mass index; TGCT cis rs74417235 0.684 rs13185173 chr5:154055081 A/G cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs6089829 0.855 rs6090203 chr20:61663632 G/A cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs2997447 0.846 rs55912918 chr1:26409801 C/T cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs9534288 0.830 rs3783202 chr13:46631869 G/A cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs17767294 0.708 rs72846802 chr6:28164842 A/G cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs9457247 1.000 rs421214 chr6:167396629 A/G cg25258033 chr6:167368657 RNASET2 0.18 4.52 0.38 1.42e-5 Crohn's disease; TGCT cis rs4824093 0.545 rs58876234 chr22:50258868 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -6.79 -0.52 4.13e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10504229 0.636 rs72649123 chr8:58045789 A/T cg21724239 chr8:58056113 NA 0.34 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.764 rs115916994 chr4:119688758 A/G cg21605333 chr4:119757512 SEC24D 1.41 7.28 0.55 3.45e-11 Cannabis dependence symptom count; TGCT cis rs9902453 0.967 rs4325622 chr17:28526475 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs75686122 0.892 rs79477585 chr8:104571733 G/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs911263 0.603 rs12890124 chr14:68781614 A/C cg18825221 chr14:68749962 RAD51L1 -0.22 -4.56 -0.38 1.22e-5 Primary biliary cholangitis; TGCT cis rs11190604 1.000 rs75063298 chr10:102213600 C/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs1048238 0.506 rs7525608 chr1:16141901 A/G cg22431228 chr1:16359049 CLCNKA -0.23 -4.52 -0.38 1.43e-5 Systolic blood pressure; TGCT cis rs11190604 1.000 rs74650218 chr10:102293830 C/T cg16342193 chr10:102329863 NA -0.41 -5.37 -0.43 3.78e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs523522 0.962 rs4767914 chr12:120993817 C/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs7829975 0.774 rs1703982 chr8:8598388 A/T cg15556689 chr8:8085844 FLJ10661 -0.64 -5.68 -0.45 9.17e-8 Mood instability; TGCT cis rs68170813 0.559 rs79543528 chr7:106891090 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs12142240 0.698 rs17413694 chr1:46818416 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs6835098 0.692 rs7657374 chr4:174065756 A/T cg08422745 chr4:174089978 GALNT7 -0.77 -8.95 -0.63 4.19e-15 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs6121246 0.909 rs6060923 chr20:30336655 A/C cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs4383453 0.539 rs4678015 chr3:123100463 A/G cg04890266 chr3:123102914 ADCY5 -0.5 -8.19 -0.59 2.68e-13 Gestational age at birth (maternal effect); TGCT cis rs6460942 0.915 rs62447642 chr7:12489147 T/C cg06484146 chr7:12443880 VWDE -0.61 -5.43 -0.44 2.87e-7 Coronary artery disease; TGCT cis rs2153535 0.601 rs1855765 chr6:8444325 C/T cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs17122693 0.748 rs72681609 chr14:51117376 A/G cg04730355 chr14:51134070 SAV1 1.33 10.91 0.7 7.71e-20 Cognitive performance; TGCT cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs3749237 0.555 rs2117939 chr3:49415179 C/A cg02487422 chr3:49467188 NICN1 0.59 6.01 0.47 1.92e-8 Resting heart rate; TGCT cis rs1008375 0.900 rs4698622 chr4:17589557 C/T cg10189774 chr4:17578691 LAP3 0.62 5.2 0.42 8.05e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2013441 0.760 rs8080827 chr17:20173936 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.55 -0.38 1.27e-5 Obesity-related traits; TGCT cis rs2404602 0.692 rs58889902 chr15:77173070 A/C cg22467129 chr15:76604101 ETFA -0.47 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs73198271 0.722 rs488566 chr8:8639575 A/G cg06671706 chr8:8559999 CLDN23 -0.35 -4.57 -0.38 1.15e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1008375 1.000 rs28545485 chr4:17645376 C/T cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4713118 0.513 rs9368547 chr6:28028067 A/G cg10876282 chr6:28092338 ZSCAN16 0.5 4.6 0.38 1.01e-5 Parkinson's disease; TGCT cis rs782590 0.935 rs6739513 chr2:55749902 G/A cg18811423 chr2:55921094 PNPT1 0.67 7.1 0.54 8.6e-11 Metabolic syndrome; TGCT cis rs904251 0.600 rs11756241 chr6:37445101 C/T cg25019722 chr6:37503610 NA -0.48 -6.95 -0.53 1.88e-10 Cognitive performance; TGCT cis rs2050392 0.771 rs303446 chr10:30728489 C/T cg13289132 chr10:30722225 MAP3K8 -0.41 -4.97 -0.41 2.15e-6 Inflammatory bowel disease; TGCT cis rs6754311 0.773 rs188680 chr2:136630989 A/G cg07169764 chr2:136633963 MCM6 -0.65 -6.06 -0.48 1.5e-8 Mosquito bite size; TGCT cis rs936229 1.000 rs936228 chr15:75132164 T/C cg10253484 chr15:75165896 SCAMP2 -0.78 -6.45 -0.5 2.28e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs40363 1.000 rs28401 chr16:3515354 C/G cg00484396 chr16:3507460 NAT15 0.44 5.08 0.41 1.36e-6 Tuberculosis; TGCT cis rs7614311 0.636 rs77639204 chr3:64005452 C/T cg22134162 chr3:63841271 THOC7 -0.43 -5.54 -0.45 1.74e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs7267979 0.903 rs2474769 chr20:25248725 C/T cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs916888 0.610 rs199453 chr17:44800946 C/T cg15921436 chr17:44337874 NA 0.41 6.25 0.49 5.98e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg12419862 chr22:24373484 LOC391322 -0.79 -8.04 -0.59 6.11e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs769267 0.930 rs2301784 chr19:19390749 G/A cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs2249625 0.508 rs60020363 chr6:72844706 C/T cg08500200 chr6:72892038 RIMS1 0.45 4.84 0.4 3.79e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs7267979 0.565 rs4815432 chr20:25556403 A/C cg03522245 chr20:25566470 NINL -0.44 -4.59 -0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2204008 0.580 rs11174421 chr12:38105138 A/G cg26384229 chr12:38710491 ALG10B 0.79 7.43 0.56 1.52e-11 Bladder cancer; TGCT cis rs6598955 0.666 rs12759434 chr1:26607123 C/T cg04990556 chr1:26633338 UBXN11 -0.9 -11.45 -0.72 3.7e-21 Obesity-related traits; TGCT cis rs2637266 0.739 rs2583040 chr10:78439388 A/C cg18941641 chr10:78392320 NA 0.4 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs6138458 1.000 rs2387361 chr20:24899905 C/T cg26195577 chr20:24973756 C20orf3 -1.2 -12.04 -0.73 1.35e-22 Blood protein levels; TGCT cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs28374715 0.578 rs13313520 chr15:41629127 T/G cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.93 -0.8 1.76e-29 Ulcerative colitis; TGCT cis rs1903068 0.853 rs10012701 chr4:56002776 A/G cg01777861 chr4:56023843 NA 0.53 6.21 0.49 7.2e-9 Endometriosis; TGCT cis rs7666738 0.830 rs28729647 chr4:99059552 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 1.000 rs2055779 chr17:57030561 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.925 rs6808036 chr3:49236439 T/G cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.79 -0.4 4.63e-6 Menarche (age at onset); TGCT cis rs12188164 1.000 rs34453673 chr5:434722 G/C cg17553881 chr5:443987 EXOC3;C5orf55 -0.39 -4.62 -0.38 9.37e-6 Cystic fibrosis severity; TGCT cis rs9309473 0.606 rs79234109 chr2:73848354 G/A cg07208825 chr2:73871855 ALMS1P 0.27 5.25 0.43 6.34e-7 Metabolite levels; TGCT cis rs7267979 0.509 rs6115218 chr20:25566485 A/G cg14121845 chr20:25566513 NINL 0.86 10.74 0.69 1.97e-19 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9296092 0.517 rs76662639 chr6:33508476 G/A cg13560919 chr6:33536144 NA -0.21 -4.52 -0.38 1.41e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6901250 0.655 rs1117046 chr6:117136978 G/C cg12892004 chr6:117198278 RFX6 0.45 5.65 0.45 1.04e-7 C-reactive protein levels; TGCT cis rs13108904 0.846 rs12643212 chr4:1224948 A/G cg03303774 chr4:1407052 NA 0.28 4.52 0.38 1.42e-5 Obesity-related traits; TGCT cis rs4919669 0.668 rs3934495 chr10:104361711 C/T cg05855489 chr10:104503620 C10orf26 0.73 4.71 0.39 6.65e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs7666738 0.830 rs28769113 chr4:98950371 T/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7731657 0.537 rs2107334 chr5:130292773 T/C cg08523029 chr5:130500466 HINT1 -0.58 -4.84 -0.4 3.8e-6 Fasting plasma glucose; TGCT cis rs4319547 0.695 rs1803290 chr12:122865029 T/C cg05707623 chr12:122985044 ZCCHC8 0.62 4.87 0.4 3.32e-6 Body mass index; TGCT cis rs10464366 0.544 rs2280667 chr7:39172228 A/C cg18850127 chr7:39170497 POU6F2 0.37 8.18 0.59 2.89e-13 IgG glycosylation; TGCT cis rs9831754 0.906 rs4680929 chr3:78387591 T/A cg06138941 chr3:78371609 NA -0.5 -5.46 -0.44 2.5e-7 Calcium levels; TGCT cis rs736408 0.716 rs2239549 chr3:52823126 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.93 0.47 2.85e-8 Bipolar disorder; TGCT cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 6.65 0.51 8.45e-10 Platelet count; TGCT cis rs7666738 0.830 rs13101352 chr4:98957544 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs13177918 0.677 rs57890152 chr5:149821472 T/C cg14059543 chr5:149831962 NA -0.72 -9.49 -0.65 2.17e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs17253792 0.822 rs10483643 chr14:56089931 G/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs9486719 1.000 rs2092096 chr6:96870919 A/G cg06623918 chr6:96969491 KIAA0776 0.98 8.77 0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs7246657 0.943 rs7257672 chr19:37823859 G/C cg18154014 chr19:37997991 ZNF793 0.74 5.08 0.42 1.34e-6 Coronary artery calcification; TGCT cis rs4566357 1.000 rs1917129 chr2:227927951 A/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.7 -0.39 6.81e-6 Coronary artery disease; TGCT cis rs599083 0.502 rs113307519 chr11:68212641 C/T cg16797656 chr11:68205561 LRP5 0.36 4.86 0.4 3.51e-6 Bone mineral density (spine); TGCT cis rs3092073 0.617 rs56324610 chr20:44564030 G/C cg23252815 chr20:44420276 WFDC3;DNTTIP1 -0.27 -4.5 -0.37 1.53e-5 Intelligence (multi-trait analysis); TGCT cis rs554111 0.963 rs710312 chr1:21042462 A/G cg08890418 chr1:21044141 KIF17 0.57 6.03 0.48 1.73e-8 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs17345786 0.861 rs74768235 chr3:101142821 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.78 0.62 1.09e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs523522 0.962 rs4766968 chr12:120947788 G/C cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg13342137 chr4:2252803 MXD4 0.17 4.47 0.37 1.71e-5 Obesity-related traits; TGCT cis rs11696501 0.688 rs6094197 chr20:44316492 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs617219 0.710 rs2591386 chr5:78561373 C/T cg23987322 chr5:78407566 BHMT 0.35 4.67 0.39 7.64e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs28595532 0.841 rs115987912 chr4:119737085 C/T cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs992157 0.764 rs2891076 chr2:219184398 C/T cg00012203 chr2:219082015 ARPC2 0.7 6.59 0.51 1.11e-9 Colorectal cancer; TGCT cis rs7586879 0.796 rs10187348 chr2:25078415 G/C cg01884057 chr2:25150051 NA 0.26 4.56 0.38 1.2e-5 Body mass index; TGCT cis rs72781680 1.000 rs72796357 chr2:24160131 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.5 0.37 1.58e-5 Lymphocyte counts; TGCT cis rs66573146 1.000 rs67405518 chr4:6965930 C/T cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs9325144 0.577 rs12314639 chr12:39119869 T/C cg26384229 chr12:38710491 ALG10B -0.62 -5.86 -0.47 3.95e-8 Morning vs. evening chronotype; TGCT cis rs477895 0.713 rs35095324 chr11:63948412 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 6.34 0.49 3.93e-9 Mean platelet volume; TGCT cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.44 7.56 0.56 7.89e-12 Schizophrenia; TGCT cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.522 rs63721860 chr17:17829576 T/C cg09796270 chr17:17721594 SREBF1 0.24 4.78 0.39 4.92e-6 Total body bone mineral density; TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg01802117 chr1:53393560 SCP2 -0.43 -5.2 -0.42 8.03e-7 Monocyte count; TGCT cis rs4499344 0.633 rs259251 chr19:33149768 G/A cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT trans rs4650994 0.525 rs2811295 chr1:178551267 C/T cg05059571 chr16:84539110 KIAA1609 0.53 10.64 0.69 3.57e-19 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6952808 1.000 rs12540579 chr7:1882227 C/A cg22963979 chr7:1858916 MAD1L1 -0.33 -5.07 -0.41 1.44e-6 Bipolar disorder and schizophrenia; TGCT cis rs6906287 0.647 rs12207209 chr6:118850375 T/G cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs9883204 0.817 rs71330995 chr3:123124513 G/A cg04890266 chr3:123102914 ADCY5 0.36 5.15 0.42 9.78e-7 Birth weight; TGCT cis rs1887596 0.663 rs9551307 chr13:27258256 A/G cg01312412 chr13:27282625 NA 0.3 5.46 0.44 2.45e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs10791323 0.633 rs2171006 chr11:133728323 T/C cg15485101 chr11:133734466 NA 0.35 4.59 0.38 1.09e-5 Childhood ear infection; TGCT cis rs2070488 0.775 rs4407366 chr3:38521425 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.69 6.13 0.48 1.09e-8 Electrocardiographic conduction measures; TGCT cis rs804280 0.638 rs36038176 chr8:11609995 C/T cg26752888 chr8:11627280 NEIL2 0.71 5.39 0.44 3.44e-7 Myopia (pathological); TGCT cis rs8180040 0.690 rs7640397 chr3:46989828 C/T cg27129171 chr3:47204927 SETD2 0.71 9.04 0.63 2.58e-15 Colorectal cancer; TGCT cis rs9325144 0.560 rs7304568 chr12:38632408 G/A cg26384229 chr12:38710491 ALG10B -0.66 -6.17 -0.48 8.94e-9 Morning vs. evening chronotype; TGCT cis rs111803315 0.744 rs113568656 chr14:60011922 C/T cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs12188164 0.965 rs56146525 chr5:442571 A/C cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs763014 0.966 rs4247097 chr16:654224 G/A cg00908189 chr16:619842 PIGQ 0.87 10.61 0.69 4.21e-19 Height; TGCT cis rs2847281 0.796 rs11876290 chr18:12777607 G/A cg23598886 chr18:12777645 NA 0.36 4.54 0.38 1.3e-5 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs28595532 0.920 rs114420700 chr4:119751297 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6831352 0.918 rs13129488 chr4:100053025 G/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs6687430 0.562 rs6676491 chr1:10633421 A/C cg17425144 chr1:10567563 PEX14 0.48 5.32 0.43 4.66e-7 Hand grip strength; TGCT cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg04025307 chr7:1156635 C7orf50 0.24 5.59 0.45 1.37e-7 Longevity;Endometriosis; TGCT cis rs9457247 0.967 rs2015864 chr6:167381476 T/C cg25258033 chr6:167368657 RNASET2 -0.18 -4.49 -0.37 1.63e-5 Crohn's disease; TGCT trans rs10809457 0.869 rs1414202 chr9:11359656 T/C cg12218771 chr1:6696166 DNAJC11 0.27 6.61 0.51 1.01e-9 Palmitic acid (16:0) levels; TGCT cis rs12541335 0.639 rs11779277 chr8:22200683 C/T cg00420450 chr8:22132641 PIWIL2 0.23 4.56 0.38 1.22e-5 Hypertriglyceridemia; TGCT cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg05368731 chr17:41323189 NBR1 1.16 13.48 0.77 4.59e-26 Menopause (age at onset); TGCT cis rs9325144 0.624 rs10783329 chr12:39113951 C/T cg10518543 chr12:38710700 ALG10B -0.49 -4.48 -0.37 1.64e-5 Morning vs. evening chronotype; TGCT cis rs60871478 1.000 rs4721124 chr7:823761 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.48 4.66 0.39 7.91e-6 Cerebrospinal P-tau181p levels; TGCT cis rs17076896 0.748 rs79332942 chr13:19929058 A/G cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs13064411 0.696 rs7624994 chr3:113228009 T/C cg18753928 chr3:113234510 CCDC52 -0.71 -5.78 -0.46 5.63e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9814567 1.000 rs13096604 chr3:134250099 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs35160687 0.901 rs10200186 chr2:86527423 C/T cg04877910 chr2:85804641 VAMP8 0.34 4.51 0.38 1.49e-5 Night sleep phenotypes; TGCT cis rs2153535 0.562 rs6901765 chr6:8455436 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs4293393 1.000 rs28362063 chr16:20365012 T/C cg26923810 chr16:20935690 LYRM1 0.22 4.76 0.39 5.28e-6 Chronic kidney disease and serum creatinine levels; TGCT cis rs59107033 0.607 rs1000368 chr3:123117165 C/T cg04890266 chr3:123102914 ADCY5 -0.36 -5.24 -0.43 6.58e-7 Lymphocyte counts; TGCT cis rs7824557 0.707 rs3808519 chr8:11142970 C/G cg21775007 chr8:11205619 TDH 0.6 5.86 0.47 3.99e-8 Retinal vascular caliber; TGCT cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg20607798 chr8:58055168 NA 0.44 4.54 0.38 1.33e-5 Developmental language disorder (linguistic errors); TGCT cis rs7659604 0.592 rs56077950 chr4:122721412 C/T cg20573242 chr4:122745356 CCNA2 0.64 5.71 0.46 7.81e-8 Type 2 diabetes; TGCT cis rs7178572 0.633 rs4886875 chr15:77838419 C/T cg22256960 chr15:77711686 NA 0.8 7.5 0.56 1.08e-11 Type 2 diabetes; TGCT cis rs700590 0.662 rs304154 chr5:88120416 T/C cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.27e-7 Educational attainment (years of education); TGCT cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs7324557 0.717 rs9510870 chr13:24384485 C/T cg16602799 chr13:25254742 ATP12A 0.57 4.45 0.37 1.93e-5 Visceral adipose tissue adjusted for BMI; TGCT trans rs4650994 0.816 rs1074896 chr1:178591190 A/G cg05059571 chr16:84539110 KIAA1609 0.41 7.51 0.56 1e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9462846 0.658 rs9471970 chr6:42913646 G/A cg13397359 chr6:42928475 GNMT 0.6 4.59 0.38 1.06e-5 Blood protein levels; TGCT trans rs797680 0.786 rs9432465 chr1:93780591 G/A cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6665290 0.669 rs12406714 chr1:227177061 T/C cg10327440 chr1:227177885 CDC42BPA -0.9 -14.92 -0.8 1.84e-29 Myeloid white cell count; TGCT cis rs6714788 0.565 rs12712063 chr2:100663281 C/T cg22139774 chr2:100720529 AFF3 -0.4 -6.5 -0.5 1.73e-9 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.641 rs12538848 chr7:106984569 G/T cg02696742 chr7:106810147 HBP1 -0.71 -5.96 -0.47 2.38e-8 Coronary artery disease; TGCT cis rs2688608 0.967 rs2675663 chr10:75660270 T/G cg19442545 chr10:75533431 FUT11 -0.3 -4.86 -0.4 3.55e-6 Inflammatory bowel disease; TGCT trans rs877282 0.583 rs7072970 chr10:822757 G/A cg22713356 chr15:30763199 NA 0.89 6.64 0.51 8.63e-10 Uric acid levels; TGCT cis rs3008870 0.755 rs2815380 chr1:67510857 A/G cg02640540 chr1:67518911 SLC35D1 -0.64 -5.71 -0.46 7.93e-8 Lymphocyte percentage of white cells; TGCT cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs2439831 0.681 rs825740 chr15:43592408 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.88 6.39 0.5 3.1e-9 Lung cancer in ever smokers; TGCT cis rs12497850 0.829 rs8926 chr3:49052785 T/A cg05785598 chr3:49045655 WDR6 0.36 4.77 0.39 5.17e-6 Parkinson's disease; TGCT cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg18654377 chr3:49208889 KLHDC8B -0.38 -4.95 -0.41 2.38e-6 Menarche (age at onset); TGCT cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg06640241 chr16:89574553 SPG7 0.76 8.51 0.61 4.88e-14 Multiple myeloma (IgH translocation); TGCT cis rs8056742 0.730 rs79334537 chr16:85084390 G/A cg00229868 chr16:85520891 NA 0.36 4.83 0.4 3.96e-6 Amyotrophic lateral sclerosis; TGCT cis rs9291683 0.567 rs12499857 chr4:9995376 G/A cg00071950 chr4:10020882 SLC2A9 0.71 8.83 0.62 8.21e-15 Bone mineral density; TGCT cis rs9486719 0.948 rs11153059 chr6:97014537 T/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs2153535 0.563 rs6942177 chr6:8534460 A/G cg07606381 chr6:8435919 SLC35B3 -0.54 -5.01 -0.41 1.86e-6 Motion sickness; TGCT cis rs4319547 0.508 rs10846826 chr12:122894987 C/T cg08088222 chr12:122070432 ORAI1 0.25 4.43 0.37 2.01e-5 Body mass index; TGCT cis rs10464366 0.746 rs6945402 chr7:39145385 A/T cg15212455 chr7:39170539 POU6F2 0.26 5.9 0.47 3.21e-8 IgG glycosylation; TGCT cis rs8037137 0.749 rs12594925 chr15:91520287 G/A cg22570213 chr15:91497863 RCCD1 0.51 4.83 0.4 3.91e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs614226 0.872 rs787827 chr12:120937794 A/G cg01236616 chr12:121019343 POP5 1.26 13.01 0.76 6.14e-25 Type 1 diabetes nephropathy; TGCT cis rs2730245 0.569 rs842692 chr7:158657228 T/C cg11984989 chr7:158649758 WDR60 1.01 8.96 0.63 4.14e-15 Height; TGCT cis rs3733585 0.699 rs6449159 chr4:9960498 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs4919669 0.668 rs10883760 chr10:104419465 G/T cg16267304 chr21:44985357 HSF2BP 0.65 6.69 0.51 6.85e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs2806561 0.765 rs2776815 chr1:23510584 C/T cg12483005 chr1:23474871 LUZP1 -0.37 -4.78 -0.39 4.97e-6 Height; TGCT cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg18252515 chr7:66147081 NA -1.21 -7.89 -0.58 1.36e-12 Diabetic kidney disease; TGCT cis rs7267979 0.789 rs62213729 chr20:25363426 C/T cg13486641 chr20:25479848 NINL 0.16 4.57 0.38 1.17e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13326165 0.760 rs1077142 chr3:52403526 A/G cg27565382 chr3:53032988 SFMBT1 0.38 5.06 0.41 1.5e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7267979 0.932 rs6107052 chr20:25530838 G/A cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10493773 0.748 rs12758511 chr1:86165987 C/T cg17807903 chr1:86174739 ZNHIT6 -0.43 -6.18 -0.49 8.29e-9 Urate levels in overweight individuals; TGCT cis rs2721195 0.683 rs6989368 chr8:145813457 A/G cg11211951 chr8:145729740 GPT 0.22 4.75 0.39 5.55e-6 Age at first birth; TGCT cis rs295140 0.597 rs1653301 chr2:201076401 A/G cg04283868 chr2:201171347 SPATS2L -0.55 -5.54 -0.45 1.69e-7 QT interval; TGCT cis rs56104184 0.775 rs117744769 chr19:49402686 G/T cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs754133 0.964 rs4759318 chr12:54420098 C/T cg16264616 chr12:54390824 NA 0.33 5.11 0.42 1.19e-6 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs10782582 0.609 rs1498311 chr1:76254726 A/C cg10523679 chr1:76189770 ACADM 0.55 5.06 0.41 1.46e-6 Daytime sleep phenotypes; TGCT cis rs2230307 0.536 rs11166384 chr1:100439890 C/T cg24955406 chr1:100503596 HIAT1 0.75 4.88 0.4 3.2e-6 Carotid intima media thickness; TGCT cis rs651907 0.535 rs58658478 chr3:101511667 G/A cg12386194 chr3:101231763 SENP7 0.46 4.5 0.37 1.57e-5 Colorectal cancer; TGCT cis rs7647973 0.577 rs6446247 chr3:49102001 A/T cg07636037 chr3:49044803 WDR6 0.81 6.68 0.51 7.37e-10 Menarche (age at onset); TGCT cis rs3796352 1.000 rs58660500 chr3:53086573 C/T cg07884673 chr3:53033167 SFMBT1 0.61 6.25 0.49 6e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6570726 0.791 rs379040 chr6:145889035 T/C cg23711669 chr6:146136114 FBXO30 0.85 9.24 0.64 8.9e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1023500 1.000 rs1023497 chr22:42340508 C/G cg04692870 chr22:42525206 CYP2D6 -0.31 -4.71 -0.39 6.46e-6 Schizophrenia; TGCT cis rs6598955 0.543 rs12125620 chr1:26552238 G/A cg04990556 chr1:26633338 UBXN11 0.8 7.3 0.55 3.01e-11 Obesity-related traits; TGCT cis rs7267979 0.966 rs2227890 chr20:25260931 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7264396 0.790 rs6121026 chr20:34266883 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs7267979 1.000 rs6515651 chr20:25414539 T/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs708547 0.836 rs1277287 chr4:57853147 C/G cg25525207 chr4:57843836 C4orf14;POLR2B -0.55 -4.87 -0.4 3.32e-6 Response to bleomycin (chromatid breaks); TGCT cis rs477895 0.838 rs7111278 chr11:64016284 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 6.93 0.53 2.04e-10 Mean platelet volume; TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs28595532 0.920 rs116516492 chr4:119734247 C/G cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs78456975 0.527 rs11901028 chr2:1557972 A/G cg12573674 chr2:1569213 NA -0.45 -4.76 -0.39 5.37e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs4319547 0.656 rs9788145 chr12:122899522 C/T cg05707623 chr12:122985044 ZCCHC8 -0.64 -4.98 -0.41 2.08e-6 Body mass index; TGCT cis rs422249 0.512 rs174577 chr11:61604814 A/C cg19610905 chr11:61596333 FADS2 0.96 9.71 0.66 6.42e-17 Trans fatty acid levels; TGCT cis rs3125734 0.572 rs3864794 chr10:64041956 A/C cg19640130 chr10:64028056 RTKN2 -0.38 -4.76 -0.39 5.25e-6 Rheumatoid arthritis; TGCT cis rs78366141 0.649 rs10428273 chr4:89672738 G/A cg01026744 chr4:89619053 NAP1L5;HERC3 1.15 5.23 0.43 6.86e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs896854 0.738 rs527234 chr8:95963798 C/G cg09323728 chr8:95962352 TP53INP1 0.45 5.32 0.43 4.6e-7 Type 2 diabetes; TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs669446 0.591 rs617521 chr1:44114199 G/T cg12908607 chr1:44402522 ARTN -0.52 -5.74 -0.46 6.79e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs10089 1.000 rs4836370 chr5:127499224 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.85 8.27 0.6 1.75e-13 Ileal carcinoids; TGCT cis rs854765 0.583 rs12603148 chr17:17865257 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.55 0.56 8.23e-12 Total body bone mineral density; TGCT cis rs8070128 0.583 rs7406982 chr17:17942613 C/T cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.87e-6 Total body bone mineral density; TGCT cis rs2075371 0.933 rs1421481 chr7:133964380 A/C cg11752832 chr7:134001865 SLC35B4 0.69 6.1 0.48 1.24e-8 Mean platelet volume; TGCT cis rs77972916 0.536 rs6751209 chr2:43588302 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.37 -5.8 -0.46 5.19e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg02487422 chr3:49467188 NICN1 0.53 4.94 0.41 2.43e-6 Menarche (age at onset); TGCT cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs617219 0.710 rs10054122 chr5:78581371 A/T cg09550809 chr5:78407562 BHMT -0.39 -5.5 -0.44 2.03e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg21724239 chr8:58056113 NA 0.41 4.87 0.4 3.33e-6 Developmental language disorder (linguistic errors); TGCT cis rs748404 0.578 rs512628 chr15:43618734 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.5e-6 Lung cancer; TGCT cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg13012494 chr21:47604986 C21orf56 0.38 4.56 0.38 1.21e-5 Testicular germ cell tumor; TGCT cis rs8103278 0.507 rs16939 chr19:46276056 C/A cg14061069 chr19:46274453 DMPK 0.62 10.94 0.7 6.57e-20 Coronary artery disease; TGCT cis rs10057188 0.814 rs10075895 chr5:77874443 C/G cg06873401 chr5:77792105 LHFPL2 -0.23 -4.51 -0.38 1.45e-5 Pulse pressure; TGCT cis rs7216064 0.953 rs9890629 chr17:65871559 G/A cg12091567 chr17:66097778 LOC651250 -0.86 -6.75 -0.52 5.09e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT trans rs12655019 0.920 rs7731829 chr5:56207711 T/C cg25190722 chr1:3801660 DFFB 0.62 7.17 0.54 5.87e-11 Breast cancer (early onset); TGCT cis rs7178572 0.568 rs12907847 chr15:77493174 C/T cg15453836 chr15:77711506 NA -0.44 -4.91 -0.4 2.86e-6 Type 2 diabetes; TGCT cis rs644799 0.582 rs473157 chr11:95596874 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.54 5.42 0.44 3e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10493773 0.566 rs11161659 chr1:86183967 T/C cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs7781977 0.554 rs7804185 chr7:50353144 T/C cg01139861 chr7:50343298 IKZF1 0.47 5.57 0.45 1.48e-7 IgG glycosylation; TGCT cis rs35306767 0.903 rs12250936 chr10:870109 C/T cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs854765 0.583 rs62064156 chr17:17822480 C/T cg09796270 chr17:17721594 SREBF1 0.28 5.66 0.45 9.89e-8 Total body bone mineral density; TGCT cis rs9972944 0.756 rs7218844 chr17:63768289 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg02353165 chr6:42928485 GNMT 0.97 10.15 0.67 5.35e-18 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7474896 0.537 rs2749588 chr10:38269457 C/G cg13720705 chr10:37990370 NA 0.34 4.54 0.38 1.31e-5 Obesity (extreme); TGCT cis rs6460942 1.000 rs6948314 chr7:12418363 T/A cg06484146 chr7:12443880 VWDE -0.59 -5.6 -0.45 1.28e-7 Coronary artery disease; TGCT cis rs7953508 0.506 rs12425869 chr12:93961353 A/G cg18151635 chr12:93972918 NA -0.19 -4.54 -0.38 1.33e-5 Pubertal anthropometrics; TGCT trans rs2970818 0.831 rs7304949 chr12:4609625 A/G cg03310518 chr7:30954522 AQP1 0.3 6.73 0.52 5.56e-10 Phosphorus levels; TGCT cis rs2197308 0.765 rs68029712 chr12:37906585 T/G cg26384229 chr12:38710491 ALG10B 0.89 8.03 0.58 6.52e-13 Morning vs. evening chronotype; TGCT cis rs13188771 0.651 rs114484620 chr5:100889920 T/C cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs8051149 0.688 rs16943320 chr16:87870379 A/G cg01412419 chr16:87856264 NA 0.49 6.1 0.48 1.24e-8 Blood metabolite levels; TGCT cis rs1505368 0.567 rs2054617 chr2:213355890 T/C cg20637307 chr2:213403960 ERBB4 0.66 7.01 0.53 1.35e-10 Symmetrical dimethylarginine levels; TGCT cis rs2075371 1.000 rs2598288 chr7:133977304 A/T cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.68e-9 Mean platelet volume; TGCT cis rs6540559 0.673 rs11805830 chr1:209984969 C/T cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs7666738 0.830 rs13108422 chr4:99059267 G/A cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6424115 0.830 rs2502991 chr1:24202318 A/G cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs11948739 0.501 rs3981332 chr5:130372203 A/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Pediatric bone mineral content (hip); TGCT cis rs1008375 1.000 rs4698634 chr4:17630192 A/C cg16339924 chr4:17578868 LAP3 -0.62 -5.11 -0.42 1.17e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.97 10.53 0.69 6.35e-19 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.662 rs908817 chr15:76639191 G/A cg22467129 chr15:76604101 ETFA 0.45 4.72 0.39 6.38e-6 Blood metabolite levels; TGCT cis rs477895 0.713 rs7952318 chr11:63961242 G/A cg23719950 chr11:63933701 MACROD1 -0.72 -6.06 -0.48 1.52e-8 Mean platelet volume; TGCT cis rs713587 0.875 rs6746013 chr2:25143649 C/G cg01884057 chr2:25150051 NA 0.4 8.18 0.59 2.88e-13 Body mass index in non-asthmatics; TGCT cis rs713587 0.967 rs10182181 chr2:25150296 C/T cg15423357 chr2:25149977 NA -0.66 -6.81 -0.52 3.78e-10 Body mass index in non-asthmatics; TGCT cis rs78487399 0.803 rs75275342 chr2:43762885 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.79 4.82 0.4 4.14e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs73198271 1.000 rs73198272 chr8:8606808 A/C ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs6735179 0.565 rs736870 chr2:1748702 T/C cg08534653 chr2:1747700 PXDN 0.54 4.45 0.37 1.92e-5 Response to antipsychotic treatment; TGCT cis rs7914558 0.966 rs11191438 chr10:104637864 C/G cg04362960 chr10:104952993 NT5C2 0.59 5.29 0.43 5.4e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT trans rs2727020 0.521 rs10839285 chr11:49496852 T/G cg11707556 chr5:10655725 ANKRD33B 0.45 9.83 0.66 3.25e-17 Coronary artery disease; TGCT cis rs6089829 0.962 rs4997812 chr20:61663153 T/G cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7824557 0.564 rs11782430 chr8:11226071 A/G cg21775007 chr8:11205619 TDH -0.63 -5.8 -0.46 5.24e-8 Retinal vascular caliber; TGCT cis rs7568458 0.870 rs2366639 chr2:85809955 A/G cg02493740 chr2:85810744 VAMP5 -0.27 -4.64 -0.38 8.64e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs346785 1.000 rs346785 chr17:74283769 C/T cg09812376 chr17:74270190 QRICH2 0.4 6.26 0.49 5.88e-9 White matter hyperintensities in ischemic stroke; TGCT cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg06697600 chr4:7070879 GRPEL1 -0.47 -4.94 -0.41 2.42e-6 Monocyte percentage of white cells; TGCT cis rs7833790 0.963 rs1451997 chr8:82774053 A/T cg17211192 chr8:82754475 SNX16 1.06 9.09 0.63 2e-15 Diastolic blood pressure; TGCT cis rs11792861 0.591 rs10979632 chr9:111732140 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 7.35 0.55 2.38e-11 Menarche (age at onset); TGCT cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs709400 1.000 rs58133129 chr14:104104759 A/G cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs8072100 0.738 rs9900123 chr17:45549055 T/C cg08085267 chr17:45401833 C17orf57 -0.47 -5.17 -0.42 8.98e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs28386778 0.799 rs2955234 chr17:61983601 A/C cg06896619 chr17:61851486 DDX42;CCDC47 0.49 4.98 0.41 2.06e-6 Prudent dietary pattern; TGCT cis rs6901250 0.807 rs339303 chr6:117176691 C/T cg12892004 chr6:117198278 RFX6 -0.55 -6.76 -0.52 4.74e-10 C-reactive protein levels; TGCT cis rs6964587 0.692 rs7807490 chr7:91773359 A/G cg17063962 chr7:91808500 NA 0.74 6.94 0.53 1.93e-10 Breast cancer; TGCT cis rs7264396 0.790 rs11697903 chr20:34272224 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs55883249 1.000 rs62119391 chr2:9712272 A/G cg23886495 chr2:9695866 ADAM17 0.82 4.8 0.4 4.47e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT trans rs1496653 0.602 rs34743949 chr3:23371636 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs9467711 0.720 rs7749823 chr6:26158079 A/C cg16898833 chr6:26189333 HIST1H4D 1.0 5.27 0.43 5.73e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs459571 0.715 rs401826 chr9:136890591 C/T cg13789015 chr9:136890014 NCRNA00094 0.41 7.53 0.56 9.26e-12 Platelet distribution width; TGCT cis rs710216 0.917 rs3754223 chr1:43419091 A/T cg03128534 chr1:43423976 SLC2A1 0.57 4.81 0.4 4.34e-6 Red cell distribution width; TGCT cis rs17345786 0.906 rs11708616 chr3:101231731 C/T cg11279151 chr3:101281821 RG9MTD1 -0.42 -8.89 -0.62 5.99e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 1.000 rs2056544 chr15:76826003 G/A cg22467129 chr15:76604101 ETFA -0.5 -5.64 -0.45 1.09e-7 Blood metabolite levels; TGCT cis rs6088580 0.634 rs1205344 chr20:32918298 G/A cg06115741 chr20:33292138 TP53INP2 -0.5 -4.46 -0.37 1.8e-5 Glomerular filtration rate (creatinine); TGCT cis rs4129767 0.869 rs4969142 chr17:76398304 G/A cg05887092 chr17:76393375 PGS1 0.22 4.64 0.38 8.72e-6 HDL cholesterol; TGCT cis rs11148252 0.574 rs3742297 chr13:53278067 T/C cg00495681 chr13:53174319 NA 0.71 7.41 0.55 1.69e-11 Lewy body disease; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg10150615 chr22:24372951 LOC391322 -0.8 -8.71 -0.62 1.62e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4819052 0.851 rs2838848 chr21:46671017 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg12310025 chr6:25882481 NA -0.67 -6.09 -0.48 1.32e-8 Intelligence (multi-trait analysis); TGCT cis rs6754311 0.593 rs7608045 chr2:136413359 T/C cg07169764 chr2:136633963 MCM6 0.67 6.1 0.48 1.24e-8 Mosquito bite size; TGCT cis rs2282802 0.635 rs199152 chr5:139539235 C/T cg01081189 chr5:139537190 NA -0.29 -5.31 -0.43 4.81e-7 Intelligence (multi-trait analysis); TGCT cis rs2862064 0.929 rs2862062 chr5:156445677 C/T cg12943317 chr5:156479607 HAVCR1 -0.4 -5.05 -0.41 1.56e-6 Platelet count; TGCT cis rs3809566 1.000 rs4775610 chr15:63332057 C/T cg00520135 chr15:63333846 TPM1 0.45 5.51 0.44 1.98e-7 Platelet count; TGCT cis rs6860806 0.507 rs272878 chr5:131671769 C/T cg24060327 chr5:131705240 SLC22A5 0.76 8.64 0.61 2.38e-14 Breast cancer; TGCT cis rs7904368 0.951 rs7905776 chr10:16853609 C/T cg14835575 chr10:16859367 RSU1 0.63 6.73 0.52 5.61e-10 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs4711350 0.954 rs943464 chr6:33731469 A/G cg13859433 chr6:33739653 LEMD2 0.33 4.49 0.37 1.58e-5 Schizophrenia; TGCT cis rs2070488 0.775 rs6599204 chr3:38525734 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.69 6.13 0.48 1.09e-8 Electrocardiographic conduction measures; TGCT cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg12667521 chr19:29218732 NA 0.54 5.72 0.46 7.65e-8 Methadone dose in opioid dependence; TGCT cis rs951366 0.873 rs823118 chr1:205723572 C/T cg14893161 chr1:205819251 PM20D1 0.37 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs4654899 0.802 rs1530946 chr1:21182540 A/G cg01072550 chr1:21505969 NA 0.45 6.64 0.51 8.8e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6752107 0.935 rs10929325 chr2:234151031 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.88 0.4 3.13e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11122272 0.735 rs2486729 chr1:231535584 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT cis rs6547741 1.000 rs10205364 chr2:27794233 C/T cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs1552244 0.882 rs17081288 chr3:10042113 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.43 -0.5 2.53e-9 Alzheimer's disease; TGCT cis rs7523050 0.643 rs17621851 chr1:109400835 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs68170813 0.527 rs78133594 chr7:107025260 T/C cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs7666738 0.791 rs11097610 chr4:99011795 C/G cg18180107 chr4:99064573 C4orf37 0.52 4.69 0.39 7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg18538332 chr22:24372958 LOC391322 0.84 7.23 0.54 4.44e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT trans rs6089829 0.925 rs13041507 chr20:61666180 T/C cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs6504663 0.586 rs60117965 chr17:48569755 G/A cg22571038 chr17:48585470 MYCBPAP 0.56 4.78 0.39 4.79e-6 Visceral fat; TGCT cis rs9653442 0.500 rs72819191 chr2:100826572 A/G cg22139774 chr2:100720529 AFF3 0.36 5.2 0.42 8.11e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs950776 1.000 rs950776 chr15:78926018 A/G cg06917634 chr15:78832804 PSMA4 0.65 4.92 0.4 2.72e-6 Sudden cardiac arrest; TGCT cis rs769267 1.000 rs2074089 chr19:19449603 G/A cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs2243480 1.000 rs316315 chr7:65591205 C/T cg18252515 chr7:66147081 NA 1.15 8.2 0.59 2.63e-13 Diabetic kidney disease; TGCT cis rs9393692 0.905 rs7747133 chr6:26293470 C/T cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.13e-9 Educational attainment; TGCT cis rs2072499 0.932 rs2736613 chr1:156196016 T/C cg25208724 chr1:156163844 SLC25A44 1.11 12.8 0.75 1.94e-24 Testicular germ cell tumor; TGCT cis rs6570726 0.791 rs443628 chr6:145883484 T/C cg23711669 chr6:146136114 FBXO30 0.9 10.01 0.67 1.19e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs17221829 0.931 rs10160803 chr11:89461859 C/T cg02982614 chr11:89391479 FOLH1B -0.3 -5.29 -0.43 5.47e-7 Anxiety in major depressive disorder; TGCT cis rs35160687 0.901 rs35281683 chr2:86526372 T/C cg03171300 chr2:86307199 POLR1A 0.32 5.56 0.45 1.61e-7 Night sleep phenotypes; TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg09737314 chr17:6899359 ALOX12 -0.46 -4.88 -0.4 3.23e-6 Tonsillectomy; TGCT cis rs1044826 0.642 rs4607068 chr3:139162994 A/G cg00490450 chr3:139108681 COPB2 0.53 4.59 0.38 1.06e-5 Obesity-related traits; TGCT cis rs9291683 0.935 rs1860911 chr4:10275057 C/T cg00071950 chr4:10020882 SLC2A9 0.42 4.57 0.38 1.16e-5 Bone mineral density; TGCT cis rs10776733 0.613 rs2364815 chr1:112106247 G/T cg21869440 chr1:111888833 C1orf88 -0.49 -4.5 -0.37 1.55e-5 Obesity-related traits; TGCT cis rs2836950 0.565 rs7276046 chr21:40581293 T/C cg11890956 chr21:40555474 PSMG1 -0.68 -6.59 -0.51 1.15e-9 Menarche (age at onset); TGCT cis rs892961 1.000 rs11077907 chr17:75400706 G/A cg05865280 chr17:75406074 SEPT9 0.29 6.82 0.52 3.6e-10 Airflow obstruction; TGCT cis rs7020830 0.931 rs13293916 chr9:37136359 C/G cg14294708 chr9:37120828 ZCCHC7 1.29 19.83 0.87 2.81e-40 Schizophrenia; TGCT cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg01802117 chr1:53393560 SCP2 0.45 5.37 0.43 3.73e-7 Monocyte count; TGCT cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg16049864 chr8:95962084 TP53INP1 -0.74 -10.56 -0.69 5.52e-19 Type 2 diabetes; TGCT cis rs1532993 0.518 rs13150153 chr4:98629384 T/C cg05340658 chr4:99064831 C4orf37 -0.38 -4.54 -0.38 1.32e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg20607798 chr8:58055168 NA 0.61 5.06 0.41 1.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs6988636 1.000 rs11988157 chr8:124194740 A/G cg22384356 chr8:124195192 FAM83A 0.44 5.98 0.47 2.26e-8 Urinary uromodulin levels; TGCT cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs3774830 0.714 rs7657964 chr4:5466327 C/G cg26943120 chr4:5472116 STK32B -0.23 -5.08 -0.42 1.34e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs12210905 1.000 rs116005859 chr6:27155485 G/A cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs76096589 0.557 rs3783409 chr14:50990400 C/T cg04730355 chr14:51134070 SAV1 1.05 4.49 0.37 1.58e-5 Diisocyanate-induced asthma; TGCT trans rs7613875 0.578 rs4688753 chr3:50074773 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs7589728 0.858 rs1914734 chr2:88529509 T/C cg04511125 chr2:88470314 THNSL2 0.57 4.74 0.39 5.67e-6 Plasma clusterin levels; TGCT cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg18305652 chr10:134549665 INPP5A 0.34 5.83 0.46 4.5e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7819412 0.838 rs4840544 chr8:10960572 C/T cg21775007 chr8:11205619 TDH -0.57 -5.6 -0.45 1.3e-7 Triglycerides; TGCT trans rs6952808 0.573 rs12668848 chr7:2020995 G/A cg24694675 chr1:76082066 NA 0.66 6.81 0.52 3.7e-10 Bipolar disorder and schizophrenia; TGCT cis rs2404602 0.716 rs12440815 chr15:76627328 C/A cg26408565 chr15:76604113 ETFA -0.45 -6.09 -0.48 1.28e-8 Blood metabolite levels; TGCT cis rs6754311 0.773 rs309125 chr2:136643555 C/T cg07169764 chr2:136633963 MCM6 0.62 5.47 0.44 2.41e-7 Mosquito bite size; TGCT cis rs7772486 0.875 rs932522 chr6:146374026 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -4.88 -0.4 3.13e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11190604 0.767 rs11190513 chr10:102165238 A/G cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.5e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11098499 0.708 rs10005237 chr4:120237897 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs7412746 0.658 rs1027699 chr1:150811712 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.69 0.39 7.01e-6 Melanoma; TGCT cis rs826838 1.000 rs12366971 chr12:38737687 T/G cg26384229 chr12:38710491 ALG10B 1.08 10.88 0.7 9.18e-20 Heart rate; TGCT cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg11644478 chr21:40555479 PSMG1 -0.53 -4.55 -0.38 1.28e-5 Cognitive function; TGCT cis rs12497850 0.897 rs7432989 chr3:49105136 A/G cg05785598 chr3:49045655 WDR6 0.36 4.8 0.4 4.48e-6 Parkinson's disease; TGCT cis rs28830936 0.510 rs7174099 chr15:42099059 A/G cg17847044 chr15:42102381 MAPKBP1 -0.19 -5.23 -0.43 7e-7 Diastolic blood pressure; TGCT trans rs17173637 0.764 rs1044616 chr7:150502075 G/C cg00050224 chr17:78327956 RNF213;LOC100294362 0.37 6.68 0.51 7.29e-10 HDL cholesterol;HDL cholesterol levels; TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg07157834 chr1:205819609 PM20D1 0.43 7.03 0.53 1.25e-10 Menarche (age at onset); TGCT cis rs2204008 0.702 rs8175764 chr12:38363690 T/C cg13010199 chr12:38710504 ALG10B 0.59 4.58 0.38 1.14e-5 Bladder cancer; TGCT cis rs7681440 0.869 rs894280 chr4:90760883 C/T cg26578617 chr4:90757533 SNCA -0.49 -5.12 -0.42 1.13e-6 Dementia with Lewy bodies; TGCT cis rs9677476 0.542 rs7595464 chr2:231967610 A/G cg07929768 chr2:232055508 NA 0.33 5.25 0.43 6.36e-7 Food antigen IgG levels; TGCT cis rs5769765 0.773 rs9616751 chr22:50222236 T/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.2 -12.89 -0.76 1.18e-24 Schizophrenia; TGCT cis rs6700896 0.522 rs4655793 chr1:66159278 C/A cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4409675 0.576 rs2474470 chr1:28234999 C/T cg23691781 chr1:28212827 C1orf38 0.26 5.44 0.44 2.76e-7 Corneal astigmatism; TGCT cis rs11249608 0.548 rs11960161 chr5:178453837 A/G cg01312482 chr5:178451176 ZNF879 -0.49 -4.76 -0.39 5.2e-6 Pubertal anthropometrics; TGCT cis rs9611565 0.546 rs2092274 chr22:42123737 A/G cg03806693 chr22:41940476 POLR3H 1.06 11.92 0.73 2.7e-22 Vitiligo; TGCT cis rs709400 0.663 rs17679475 chr14:103916958 A/G cg26031613 chr14:104095156 KLC1 0.84 9.19 0.64 1.13e-15 Body mass index; TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg09177884 chr7:1199841 ZFAND2A -0.63 -6.54 -0.51 1.45e-9 Longevity;Endometriosis; TGCT cis rs155076 1.000 rs261423 chr13:21852331 A/C cg14456004 chr13:21872349 NA -1.34 -11.21 -0.71 1.42e-20 White matter hyperintensity burden; TGCT cis rs763121 0.925 rs5757251 chr22:39100128 G/A cg06022373 chr22:39101656 GTPBP1 0.69 6.65 0.51 8.39e-10 Menopause (age at onset); TGCT cis rs6430585 0.591 rs309170 chr2:136672775 C/T cg07169764 chr2:136633963 MCM6 1.19 11.56 0.72 2.02e-21 Corneal structure; TGCT cis rs9926296 0.605 rs1800287 chr16:89858525 C/G cg26513180 chr16:89883248 FANCA 1.05 14.87 0.8 2.47e-29 Vitiligo; TGCT cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg05368731 chr17:41323189 NBR1 1.11 11.14 0.71 2.11e-20 Menopause (age at onset); TGCT cis rs514406 0.505 rs436363 chr1:53172163 T/C cg08859206 chr1:53392774 SCP2 -0.34 -4.86 -0.4 3.53e-6 Monocyte count; TGCT cis rs12477438 0.520 rs6542870 chr2:99796638 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs9811920 0.535 rs704571 chr3:99481946 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.39 4.6 0.38 1.04e-5 Axial length; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg00024416 chr22:24240387 NA -0.26 -5.11 -0.42 1.2e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs5769707 0.667 rs4824069 chr22:50030325 T/C cg05373962 chr22:49881684 NA -0.31 -5.37 -0.43 3.8e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6570726 0.967 rs9403706 chr6:145795187 C/T cg23711669 chr6:146136114 FBXO30 -0.66 -6.06 -0.48 1.52e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6586111 1.000 rs6586111 chr10:82377590 T/C cg03086067 chr10:82368399 SH2D4B -0.23 -4.51 -0.38 1.51e-5 Capecitabine sensitivity; TGCT cis rs2288073 0.965 rs6545340 chr2:24422269 C/G cg05570707 chr2:24270316 C2orf44 -0.5 -4.47 -0.37 1.72e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs2120019 1.000 rs12910644 chr15:75358388 A/G cg11632617 chr15:75315747 PPCDC -0.33 -4.59 -0.38 1.07e-5 Blood trace element (Zn levels); TGCT cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs7312933 0.558 rs11181501 chr12:42822671 G/A cg19980929 chr12:42632907 YAF2 0.42 5.91 0.47 3.05e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9419702 0.568 rs7075233 chr10:133545170 A/G cg23460707 chr10:133558971 NA -0.42 -4.94 -0.41 2.43e-6 Survival in rectal cancer; TGCT cis rs3741404 0.537 rs1123251 chr11:63917601 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.68 -5.92 -0.47 2.98e-8 Platelet count; TGCT cis rs12136530 0.774 rs4912097 chr1:19784410 C/G cg18923740 chr1:19971790 NBL1 0.36 4.44 0.37 1.96e-5 Lead levels in blood; TGCT cis rs637571 0.522 rs7105628 chr11:65763067 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.67 6.68 0.51 7.19e-10 Eosinophil percentage of white cells; TGCT cis rs77972916 0.536 rs11679731 chr2:43589064 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.32 -4.53 -0.38 1.36e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.35 0.43 4.08e-7 Prudent dietary pattern; TGCT cis rs1150668 0.768 rs1233713 chr6:28198281 A/G cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.61 -0.38 9.84e-6 Pubertal anthropometrics; TGCT cis rs11671005 0.779 rs11670125 chr19:58987390 G/T cg07764513 chr19:58919909 ZNF584 -0.71 -4.59 -0.38 1.06e-5 Mean platelet volume; TGCT cis rs4936891 1.000 rs4936890 chr11:123914742 G/A cg22125253 chr11:123886957 OR10G4 -0.2 -4.51 -0.38 1.47e-5 Male fertility; TGCT cis rs7267979 1.000 rs6050632 chr20:25432601 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.558 rs62435775 chr6:146136415 G/C cg13319975 chr6:146136371 FBXO30 -0.69 -6.28 -0.49 5.18e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.769 rs6772452 chr3:49040462 A/G cg07636037 chr3:49044803 WDR6 0.8 6.69 0.51 6.94e-10 Menarche (age at onset); TGCT cis rs12188164 0.965 rs72717438 chr5:448663 C/T cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs4975616 0.804 rs459961 chr5:1337106 T/A cg07493874 chr5:1342172 CLPTM1L -0.28 -6.85 -0.52 3.06e-10 Lung cancer; TGCT cis rs1580019 0.921 rs1580023 chr7:32497881 G/A cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.61 0.56 5.93e-12 Cognitive ability; TGCT cis rs5750830 0.594 rs9611169 chr22:39783027 C/T cg11247378 chr22:39784982 NA -0.65 -9.02 -0.63 2.89e-15 Intelligence (multi-trait analysis); TGCT cis rs74233809 1.000 rs74233296 chr10:104655350 T/C cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs2439831 0.867 rs6493082 chr15:43634808 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs7822232 0.908 rs7821112 chr8:145147169 G/A cg14631276 chr8:145163102 KIAA1875 0.56 5.05 0.41 1.55e-6 Blood metabolite levels; TGCT cis rs4665809 0.877 rs34536218 chr2:26287376 T/A cg25036284 chr2:26402008 FAM59B 0.58 4.58 0.38 1.12e-5 Gut microbiome composition (summer); TGCT cis rs73198271 0.653 rs10087633 chr8:8660444 A/G cg06671706 chr8:8559999 CLDN23 -0.36 -4.61 -0.38 9.98e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs10501293 1.000 rs1559762 chr11:43128541 C/T cg03447554 chr11:43094025 NA 0.49 6.9 0.53 2.37e-10 Cognitive performance; TGCT trans rs208515 0.525 rs10944859 chr6:66665197 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.9 9.56 0.65 1.46e-16 Exhaled nitric oxide levels; TGCT cis rs9308731 0.644 rs1837369 chr2:111874276 C/T cg04202892 chr2:111875749 ACOXL 0.54 6.22 0.49 6.93e-9 Chronic lymphocytic leukemia; TGCT cis rs1912483 0.505 rs11079772 chr17:45393739 A/C cg08085267 chr17:45401833 C17orf57 0.67 8.23 0.59 2.19e-13 Coronary artery disease; TGCT cis rs6500602 0.727 rs11076836 chr16:4569331 G/A cg09549813 chr16:4587862 C16orf5 -0.28 -4.51 -0.38 1.5e-5 Schizophrenia; TGCT cis rs929354 0.742 rs3808316 chr7:156944787 C/G cg05182265 chr7:156933206 UBE3C -0.38 -8.43 -0.6 7.5e-14 Body mass index; TGCT cis rs554111 0.636 rs10916935 chr1:21432112 T/C cg01072550 chr1:21505969 NA 0.36 5.46 0.44 2.51e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2235642 0.821 rs2281234 chr16:1602938 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.42 -0.44 2.97e-7 Coronary artery disease; TGCT cis rs4925386 0.959 rs6121989 chr20:60916713 A/T cg06026331 chr20:60912101 LAMA5 -0.3 -5.4 -0.44 3.2e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs9393692 0.846 rs9366651 chr6:26336696 G/T cg13736514 chr6:26305472 NA -0.35 -4.95 -0.41 2.4e-6 Educational attainment; TGCT cis rs210152 0.588 rs3119024 chr6:33450034 T/C cg16739976 chr6:34101401 GRM4 -0.57 -4.72 -0.39 6.15e-6 Schizophrenia; TGCT cis rs10858047 0.883 rs6701427 chr1:115216886 C/T cg12756093 chr1:115239321 AMPD1 -0.49 -5.13 -0.42 1.08e-6 Autism; TGCT cis rs11167764 1.000 rs6887599 chr5:141484349 G/A cg02659431 chr5:141694439 SPRY4 -0.21 -4.6 -0.38 1.03e-5 Crohn's disease; TGCT cis rs1670533 1.000 rs10084890 chr4:1053934 C/G cg27284194 chr4:1044797 NA -0.7 -6.08 -0.48 1.34e-8 Recombination rate (females); TGCT cis rs9527 0.615 rs10883800 chr10:104671212 A/C cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs6582630 0.519 rs4002438 chr12:38484880 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7617773 0.780 rs11720026 chr3:48377921 T/C cg11946769 chr3:48343235 NME6 0.82 6.99 0.53 1.49e-10 Coronary artery disease; TGCT cis rs3796352 1.000 rs13072457 chr3:53102389 G/A cg27565382 chr3:53032988 SFMBT1 0.45 4.76 0.39 5.25e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11935103 0.636 rs9997314 chr4:187297232 T/C cg16785698 chr4:186456103 PDLIM3 0.44 4.47 0.37 1.74e-5 Response to citalopram treatment; TGCT trans rs66573146 1.000 rs7686186 chr4:6986094 C/T cg07817883 chr1:32538562 TMEM39B 1.66 8.29 0.6 1.56e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs9926296 0.712 rs258319 chr16:89732024 A/T cg03388025 chr16:89894329 SPIRE2 -0.35 -5.05 -0.41 1.54e-6 Vitiligo; TGCT cis rs950169 0.959 rs66801143 chr15:84736657 C/T cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.14e-8 Schizophrenia; TGCT cis rs7474896 0.583 rs10827817 chr10:37997974 A/G cg25427524 chr10:38739819 LOC399744 -0.28 -4.45 -0.37 1.91e-5 Obesity (extreme); TGCT cis rs6582630 0.519 rs11495724 chr12:38337507 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs17376456 0.569 rs13186432 chr5:93336940 G/A cg21475434 chr5:93447410 FAM172A -0.65 -5.93 -0.47 2.75e-8 Diabetic retinopathy; TGCT cis rs35306767 0.623 rs12354710 chr10:1114020 C/T cg20503657 chr10:835505 NA 0.53 5.6 0.45 1.33e-7 Eosinophil percentage of granulocytes; TGCT cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg03806693 chr22:41940476 POLR3H -1.12 -12.62 -0.75 5.47e-24 Vitiligo; TGCT cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg11845111 chr2:191398756 TMEM194B -0.36 -5.44 -0.44 2.73e-7 Pulse pressure; TGCT cis rs9372253 1.000 rs11153232 chr6:110716252 G/T cg19196401 chr6:110721138 DDO 0.5 7.33 0.55 2.59e-11 Platelet distribution width; TGCT cis rs17826219 0.561 rs4085382 chr17:29071202 T/C cg13385521 chr17:29058706 SUZ12P 0.82 5.04 0.41 1.61e-6 Body mass index; TGCT cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg09222892 chr1:25734099 RHCE -0.44 -7.08 -0.54 9.31e-11 Erythrocyte sedimentation rate; TGCT cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs17741873 1.000 rs17741873 chr10:75653800 G/T cg07699608 chr10:75541558 CHCHD1 0.66 5.04 0.41 1.59e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.53 4.94 0.41 2.44e-6 Prudent dietary pattern; TGCT cis rs7927592 0.731 rs7108376 chr11:68347870 A/G cg16797656 chr11:68205561 LRP5 -0.25 -4.5 -0.37 1.53e-5 Total body bone mineral density; TGCT cis rs3096299 0.679 rs3102338 chr16:89442250 C/G cg06640241 chr16:89574553 SPG7 0.63 5.73 0.46 7.09e-8 Multiple myeloma (IgH translocation); TGCT cis rs57920188 0.537 rs72852529 chr1:4076373 A/G cg20703997 chr1:4087676 NA 0.47 5.8 0.46 5.14e-8 Interleukin-17 levels; TGCT cis rs17767294 0.708 rs72849206 chr6:28172704 A/G cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs7267979 0.899 rs2104734 chr20:25526668 A/G cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT trans rs931812 0.895 rs4734013 chr8:101908687 A/C cg20993868 chr7:22813445 NA 0.4 8.85 0.62 7.57e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg06601766 chr17:61851465 DDX42;CCDC47 -0.51 -4.48 -0.37 1.66e-5 Prudent dietary pattern; TGCT cis rs7584330 0.910 rs6757376 chr2:238400036 G/C cg14458575 chr2:238380390 NA 0.39 5.56 0.45 1.61e-7 Prostate cancer; TGCT cis rs9894429 0.608 rs7406382 chr17:79597786 T/C cg18240062 chr17:79603768 NPLOC4 0.58 5.12 0.42 1.15e-6 Eye color traits; TGCT cis rs10791097 0.720 rs4936121 chr11:130733878 A/G cg05962950 chr11:130786565 SNX19 0.92 10.76 0.69 1.76e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4455778 0.580 rs7783068 chr7:49120791 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs4665809 0.652 rs6727974 chr2:26524639 A/G cg22920501 chr2:26401640 FAM59B 0.78 6.23 0.49 6.54e-9 Gut microbiome composition (summer); TGCT cis rs2688608 0.620 rs12253408 chr10:75495956 G/T cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs9467603 0.592 rs1184498 chr6:25864882 G/C cg03517284 chr6:25882590 NA -0.73 -4.73 -0.39 5.97e-6 Intelligence (multi-trait analysis); TGCT cis rs4499344 0.730 rs417823 chr19:33104561 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.66 0.61 2.12e-14 Mean platelet volume; TGCT cis rs2050392 0.624 rs2489842 chr10:30721991 T/C cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT cis rs9486719 1.000 rs11152968 chr6:96908653 A/G cg06623918 chr6:96969491 KIAA0776 0.98 8.77 0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs9311474 0.652 rs352161 chr3:52221849 C/A cg07507251 chr3:52567010 NT5DC2 0.35 4.52 0.38 1.42e-5 Electroencephalogram traits; TGCT cis rs597539 0.654 rs655816 chr11:68626405 A/G cg21963583 chr11:68658836 MRPL21 0.38 6.24 0.49 6.45e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg03396347 chr1:1875803 NA -0.37 -6.62 -0.51 9.64e-10 Body mass index; TGCT cis rs112217694 1.000 rs75159306 chr4:104649474 G/C cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs4523957 0.620 rs1565764 chr17:2074303 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.46 -0.37 1.8e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6684514 1.000 rs12117903 chr1:156311165 G/T cg20302342 chr1:156215951 PAQR6 0.36 4.77 0.39 5.1e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs523522 0.962 rs3742052 chr12:120966921 A/G cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs2836974 0.897 rs36113648 chr21:40555497 G/A cg11644478 chr21:40555479 PSMG1 1.02 10.59 0.69 4.75e-19 Cognitive function; TGCT cis rs17401966 0.540 rs6541094 chr1:10467074 G/A cg19773385 chr1:10388646 KIF1B -0.23 -5.46 -0.44 2.52e-7 Hepatocellular carcinoma; TGCT cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg23758822 chr17:41437982 NA 0.79 7.39 0.55 1.87e-11 Menopause (age at onset); TGCT cis rs12497850 1.000 rs4858828 chr3:48724811 C/T cg16497277 chr3:49208875 KLHDC8B -0.5 -4.78 -0.39 4.87e-6 Parkinson's disease; TGCT cis rs7666738 0.830 rs11932942 chr4:98998939 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg05985448 chr10:134359359 INPP5A 0.22 4.83 0.4 3.89e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12497850 0.931 rs6446196 chr3:49004723 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.5 0.44 2.06e-7 Parkinson's disease; TGCT cis rs3003334 1 rs3003334 chr1:24199869 G/A cg15997130 chr1:24165203 NA 0.85 9.35 0.64 4.75e-16 Eosinophil percentage of white cells;Eosinophil percentage of granulocytes; TGCT cis rs2153535 0.580 rs915352 chr6:8442766 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs1153858 1.000 rs1820518 chr15:45694579 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs6450176 0.909 rs7732139 chr5:53292017 G/A ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2806561 0.734 rs2143156 chr1:23374629 T/G cg12483005 chr1:23474871 LUZP1 0.38 4.76 0.39 5.3e-6 Height; TGCT cis rs66561647 0.597 rs34390452 chr8:128940141 G/A cg05480350 chr8:128972681 MIR1205;PVT1 0.23 4.71 0.39 6.62e-6 Hemoglobin concentration; TGCT cis rs10089 1.000 rs3805612 chr5:127505316 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.85 8.27 0.6 1.8e-13 Ileal carcinoids; TGCT cis rs11785400 0.793 rs7000765 chr8:143722457 G/A cg24634471 chr8:143751801 JRK 0.54 5.27 0.43 5.82e-7 Schizophrenia; TGCT trans rs57221529 0.713 rs56328416 chr5:591138 G/A cg25482853 chr8:67687455 SGK3 1.21 10.3 0.68 2.37e-18 Lung disease severity in cystic fibrosis; TGCT cis rs2075371 0.965 rs1862049 chr7:133978344 A/T cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.68e-9 Mean platelet volume; TGCT cis rs6879260 0.963 rs11738924 chr5:179727308 A/G cg23248424 chr5:179741104 GFPT2 -0.35 -6.32 -0.49 4.31e-9 Height; TGCT cis rs7043114 0.525 rs7045409 chr9:95201540 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -5.46 -0.44 2.48e-7 Height; TGCT cis rs611744 0.836 rs684412 chr8:109210905 T/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs909674 0.818 rs8137426 chr22:39844350 T/G cg24399712 chr22:39784796 NA -1.05 -10.97 -0.7 5.63e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg09359103 chr1:154839909 KCNN3 -0.67 -12.42 -0.74 1.61e-23 Prostate cancer; TGCT cis rs9399137 0.507 rs61738647 chr6:135282735 T/C cg24558204 chr6:135376177 HBS1L 0.46 4.68 0.39 7.32e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs11098499 0.542 rs10440343 chr4:120309787 G/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs66823261 0.741 rs7841786 chr8:191746 A/C cg27532244 chr8:182981 ZNF596;RPL23AP53 -0.83 -7.04 -0.53 1.16e-10 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs854765 0.583 rs8078583 chr17:17811465 C/T cg09796270 chr17:17721594 SREBF1 0.28 5.66 0.45 1.02e-7 Total body bone mineral density; TGCT cis rs67311347 1.000 rs9874006 chr3:40471596 G/A cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs10927875 0.541 rs1048245 chr1:16341354 T/G cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs2014572 0.967 rs8112572 chr19:57759612 T/C cg24459738 chr19:57751996 ZNF805 -0.56 -5.6 -0.45 1.29e-7 Hyperactive-impulsive symptoms; TGCT cis rs9611565 0.649 rs2413659 chr22:42164862 A/G cg17554472 chr22:41940697 POLR3H 0.43 4.54 0.38 1.3e-5 Vitiligo; TGCT cis rs11085466 1.000 rs73552479 chr19:21778816 G/T cg01048962 chr19:21646470 NA -0.59 -4.61 -0.38 9.72e-6 Colorectal or endometrial cancer; TGCT cis rs11235843 0.636 rs10736793 chr11:73402576 A/C cg18195628 chr11:73498948 MRPL48 -0.64 -4.52 -0.38 1.42e-5 Hand grip strength; TGCT cis rs7336332 0.598 rs7669 chr13:28009851 C/T cg22138327 chr13:27999177 GTF3A 0.79 6.44 0.5 2.37e-9 Weight; TGCT cis rs2228479 0.850 rs62056068 chr16:89909737 C/T cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs9921338 0.961 rs9937269 chr16:11416679 A/G cg00044050 chr16:11439710 C16orf75 0.97 7.45 0.56 1.4e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs2730245 0.527 rs842695 chr7:158662182 G/A cg11984989 chr7:158649758 WDR60 1.01 7.87 0.58 1.48e-12 Height; TGCT cis rs6964587 1.000 rs13230588 chr7:91615427 C/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs2842992 0.724 rs9365097 chr6:160211259 G/A cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs9733 0.596 rs12086472 chr1:150697710 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs933688 1.000 rs6867091 chr5:90734333 C/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.91 8.42 0.6 7.74e-14 Smoking behavior; TGCT cis rs9910055 0.529 rs183462 chr17:42183376 G/C cg19774624 chr17:42201019 HDAC5 0.73 6.89 0.53 2.53e-10 Total body bone mineral density; TGCT cis rs853679 0.546 rs175597 chr6:27810626 T/C cg08798685 chr6:27730294 NA -0.34 -4.77 -0.39 5.13e-6 Depression; TGCT cis rs1775715 0.737 rs2778650 chr10:32106851 A/G cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.38e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs5758659 0.714 rs5758589 chr22:42518382 A/G cg15557168 chr22:42548783 NA 0.18 4.56 0.38 1.23e-5 Cognitive function; TGCT cis rs2549003 0.966 rs2706385 chr5:131831766 T/G cg02551604 chr5:131831745 NA 0.9 12.32 0.74 2.92e-23 Asthma (sex interaction); TGCT cis rs4824093 0.610 rs4141437 chr22:50243719 C/G cg22709217 chr22:50311962 ALG12;CRELD2 1.06 6.46 0.5 2.18e-9 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2404602 0.669 rs12916324 chr15:77179603 G/A cg22467129 chr15:76604101 ETFA -0.47 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs10832963 0.924 rs10500834 chr11:18638712 A/T cg09201001 chr11:18656081 SPTY2D1 1.05 11.63 0.72 1.34e-21 Breast cancer; TGCT cis rs514406 0.861 rs7526275 chr1:53245849 C/T cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs1348850 0.567 rs1405714 chr2:178538584 A/G cg22681709 chr2:178499509 PDE11A 0.5 6.59 0.51 1.11e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9831754 1.000 rs9831754 chr3:78353591 A/C cg06138941 chr3:78371609 NA -0.44 -4.46 -0.37 1.78e-5 Calcium levels; TGCT cis rs11190604 0.767 rs11190520 chr10:102175309 T/C cg16005271 chr10:102321736 NA 0.45 4.57 0.38 1.15e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11785400 0.731 rs4736363 chr8:143742112 C/A cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs2295359 1.000 rs4655524 chr1:67629469 G/A cg12940439 chr1:67600707 NA 0.54 5.78 0.46 5.78e-8 Psoriasis; TGCT cis rs17601876 0.814 rs12050767 chr15:51557257 T/C cg19946085 chr15:51559439 CYP19A1 -0.33 -5.04 -0.41 1.64e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs9926296 0.548 rs12447465 chr16:89829895 C/T cg04287289 chr16:89883240 FANCA 0.92 11.67 0.72 1.11e-21 Vitiligo; TGCT cis rs6933660 0.646 rs9383899 chr6:151781022 G/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.58 -5.47 -0.44 2.41e-7 Menarche (age at onset); TGCT cis rs6095298 0.595 rs6095325 chr20:47453602 G/T cg12307787 chr20:48099359 KCNB1 -0.44 -4.56 -0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.558 rs11181422 chr12:42718552 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.7 -0.46 8.16e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6484504 0.532 rs2761589 chr11:31311429 C/G cg14844989 chr11:31128820 NA 0.23 4.56 0.38 1.23e-5 Red blood cell count; TGCT cis rs7523273 0.565 rs2796280 chr1:207889345 C/T cg22525895 chr1:207977042 MIR29B2 -0.35 -5.72 -0.46 7.49e-8 Schizophrenia; TGCT cis rs1784581 0.651 rs1784589 chr6:162389571 A/G cg17173639 chr6:162384350 PARK2 -0.47 -8.16 -0.59 3.15e-13 Itch intensity from mosquito bite; TGCT cis rs11030122 0.547 rs12270732 chr11:3952901 C/A cg18678763 chr11:4115507 RRM1 -0.39 -4.76 -0.39 5.24e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs2033711 0.870 rs4801270 chr19:58932762 C/A cg12042659 chr19:58951599 ZNF132 0.52 4.82 0.4 4.18e-6 Uric acid clearance; TGCT cis rs875971 0.862 rs801195 chr7:66026115 A/G cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs514406 0.505 rs856721 chr1:53162156 C/A cg24675658 chr1:53192096 ZYG11B -0.74 -8.28 -0.6 1.65e-13 Monocyte count; TGCT cis rs10197940 0.624 rs4461258 chr2:152429679 A/G cg19508488 chr2:152266495 RIF1 -0.68 -6.33 -0.49 4.02e-9 Lung cancer; TGCT cis rs854765 0.583 rs9913724 chr17:17819101 A/G cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.83e-6 Total body bone mineral density; TGCT cis rs10992471 0.528 rs2296666 chr9:95274261 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.52 4.99 0.41 1.98e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg01765077 chr12:122356316 WDR66 0.32 4.64 0.38 8.82e-6 Mean corpuscular volume; TGCT cis rs9309473 0.606 rs78941213 chr2:73885137 C/T cg07208825 chr2:73871855 ALMS1P 0.29 5.72 0.46 7.52e-8 Metabolite levels; TGCT cis rs11148252 0.553 rs9536219 chr13:53227301 C/T cg00495681 chr13:53174319 NA 0.64 6.46 0.5 2.15e-9 Lewy body disease; TGCT cis rs9926296 0.687 rs258317 chr16:89732238 C/T cg03388025 chr16:89894329 SPIRE2 -0.36 -5.28 -0.43 5.54e-7 Vitiligo; TGCT cis rs208515 0.556 rs10455193 chr6:66691456 G/A cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs17125944 0.615 rs7145392 chr14:53321016 G/A cg00686598 chr14:53173677 PSMC6 -0.82 -4.85 -0.4 3.68e-6 Alzheimer's disease (late onset); TGCT cis rs3008870 0.959 rs1886686 chr1:67390468 C/G cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs651907 0.535 rs13094911 chr3:101519021 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs453301 0.522 rs2929455 chr8:9083433 A/T cg06636001 chr8:8085503 FLJ10661 -0.52 -4.57 -0.38 1.14e-5 Joint mobility (Beighton score); TGCT cis rs12762955 0.529 rs2387213 chr10:1051420 C/T cg18964960 chr10:1102726 WDR37 0.68 5.99 0.47 2.12e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs7937682 0.575 rs1346180 chr11:111715570 G/C cg09085632 chr11:111637200 PPP2R1B 0.94 8.94 0.63 4.57e-15 Primary sclerosing cholangitis; TGCT cis rs11252926 0.537 rs4881274 chr10:459940 G/A cg18196295 chr10:418757 DIP2C 0.29 4.76 0.39 5.4e-6 Psychosis in Alzheimer's disease; TGCT cis rs4689388 0.926 rs11732178 chr4:6292643 G/C cg00701064 chr4:6280414 WFS1 0.44 5.74 0.46 6.95e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6964587 1.000 rs12537846 chr7:91721581 C/T cg17063962 chr7:91808500 NA -0.86 -9.39 -0.64 3.79e-16 Breast cancer; TGCT cis rs10504229 0.593 rs4738567 chr8:57997033 A/C cg08280861 chr8:58055591 NA 0.34 4.79 0.39 4.75e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs10202478 chr2:26276049 T/C cg04944784 chr2:26401820 FAM59B -0.67 -6.05 -0.48 1.62e-8 Gut microbiome composition (summer); TGCT cis rs2282802 0.685 rs6893253 chr5:139661279 T/C cg01081189 chr5:139537190 NA 0.28 5.06 0.41 1.46e-6 Intelligence (multi-trait analysis); TGCT cis rs3540 0.533 rs4932342 chr15:90982923 C/T cg22089800 chr15:90895588 ZNF774 0.76 8.11 0.59 4.19e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9916302 0.706 rs4488484 chr17:37717377 A/T cg07936489 chr17:37558343 FBXL20 0.84 6.08 0.48 1.35e-8 Glomerular filtration rate (creatinine); TGCT cis rs9457247 1.000 rs430477 chr6:167389851 T/C cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs1062177 0.826 rs1549920 chr5:151140844 A/T cg00977110 chr5:151150581 G3BP1 0.41 4.66 0.39 8.17e-6 Preschool internalizing problems; TGCT cis rs78487399 0.634 rs77881454 chr2:43757293 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.09 -0.42 1.29e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7617773 0.817 rs9847953 chr3:48282695 A/G cg11946769 chr3:48343235 NME6 0.72 6.23 0.49 6.77e-9 Coronary artery disease; TGCT cis rs7412746 0.611 rs4970931 chr1:150910727 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs2742417 1.000 rs2742436 chr3:45741397 T/C cg04837898 chr3:45731254 SACM1L -0.51 -5.22 -0.42 7.15e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7178572 0.568 rs1493700 chr15:77629060 T/C cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs17001868 0.892 rs73167023 chr22:40799954 T/C cg07138101 chr22:40742427 ADSL 0.71 4.72 0.39 6.31e-6 Mammographic density (dense area); TGCT cis rs2467099 0.504 rs2608881 chr17:73936653 C/G cg02678768 chr17:74002944 EVPL 0.28 4.85 0.4 3.58e-6 Systolic blood pressure; TGCT cis rs9611565 0.729 rs203320 chr22:41913477 T/C cg06634786 chr22:41940651 POLR3H -0.76 -7.51 -0.56 1e-11 Vitiligo; TGCT cis rs68170813 0.523 rs79607134 chr7:107033619 A/T cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs5769707 0.967 rs4524218 chr22:50018639 G/A cg05373962 chr22:49881684 NA -0.3 -6.29 -0.49 5.08e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs11209002 0.614 rs4655515 chr1:67566898 T/C cg02640540 chr1:67518911 SLC35D1 0.59 5.0 0.41 1.92e-6 Crohn's disease; TGCT cis rs1784581 0.588 rs9885762 chr6:162411954 G/A cg17173639 chr6:162384350 PARK2 0.39 6.51 0.5 1.7e-9 Itch intensity from mosquito bite; TGCT cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg11890956 chr21:40555474 PSMG1 0.76 7.42 0.55 1.64e-11 Cognitive function; TGCT cis rs8062405 0.757 rs2411453 chr16:28632021 A/C cg09754948 chr16:28834200 ATXN2L -0.57 -4.6 -0.38 1.04e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9467773 0.565 rs6925047 chr6:26521435 C/G cg05738196 chr6:26577821 NA 0.75 9.2 0.64 1.09e-15 Intelligence (multi-trait analysis); TGCT cis rs7246657 0.943 rs10405407 chr19:37839164 C/T cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.3e-7 Coronary artery calcification; TGCT cis rs10466239 0.730 rs12221341 chr10:43857330 C/G cg08951903 chr10:44070173 ZNF239 -0.79 -4.92 -0.4 2.72e-6 Telomere length; TGCT cis rs7255045 0.788 rs1124820 chr19:12957114 G/A cg23899408 chr19:12877188 HOOK2 -0.59 -4.79 -0.4 4.63e-6 Mean corpuscular volume; TGCT cis rs60843830 1.000 rs17714252 chr2:285471 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.7 0.52 6.46e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7524258 0.900 rs12035586 chr1:7273020 C/T cg04342483 chr1:7259290 CAMTA1 0.32 4.81 0.4 4.36e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs73001065 0.636 rs56241616 chr19:19506092 C/T cg03709012 chr19:19516395 GATAD2A 0.88 4.69 0.39 7.11e-6 LDL cholesterol; TGCT cis rs1215050 0.740 rs6855827 chr4:99065706 G/A cg17366294 chr4:99064904 C4orf37 0.58 6.15 0.48 9.93e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9814567 1.000 rs9289476 chr3:134237103 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -9.2 -0.64 1.11e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs13064411 0.591 rs7628945 chr3:113201754 A/T cg18753928 chr3:113234510 CCDC52 -0.54 -4.58 -0.38 1.12e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs12497850 0.829 rs8926 chr3:49052785 T/A cg06212747 chr3:49208901 KLHDC8B 0.61 5.66 0.45 9.84e-8 Parkinson's disease; TGCT cis rs28374715 0.681 rs7168307 chr15:41620534 A/G cg18705301 chr15:41695430 NDUFAF1 -0.87 -13.89 -0.78 4.85e-27 Ulcerative colitis; TGCT cis rs9517320 0.534 rs9554474 chr13:99140871 G/A cg07423050 chr13:99094983 FARP1 -0.3 -5.8 -0.46 5.15e-8 Longevity; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg24846343 chr22:24311635 DDTL 0.24 6.05 0.48 1.57e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8177253 1.000 rs8177252 chr3:133480174 C/A cg11941060 chr3:133502564 NA -0.29 -6.14 -0.48 1.02e-8 Iron status biomarkers; TGCT cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg06139259 chr16:4526053 HMOX2;NMRAL1 0.27 4.85 0.4 3.56e-6 Schizophrenia; TGCT trans rs561341 0.941 rs2428338 chr17:30299629 T/C cg20587970 chr11:113659929 NA -1.03 -12.7 -0.75 3.52e-24 Hip circumference adjusted for BMI; TGCT cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs765787 0.530 rs2458224 chr15:45522130 T/C cg24006582 chr15:45444508 DUOX1 -0.26 -5.63 -0.45 1.15e-7 Uric acid levels; TGCT cis rs858239 0.539 rs6955726 chr7:23186691 A/G cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg06238570 chr21:40685208 BRWD1 -0.8 -9.1 -0.63 1.91e-15 Cognitive function; TGCT cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg18654377 chr3:49208889 KLHDC8B -0.38 -4.92 -0.4 2.69e-6 Menarche (age at onset); TGCT cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg23719950 chr11:63933701 MACROD1 -0.69 -5.67 -0.45 9.32e-8 Mean platelet volume; TGCT cis rs9581857 0.615 rs3759435 chr13:27996813 T/G cg22138327 chr13:27999177 GTF3A 0.8 6.55 0.51 1.38e-9 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6570726 0.516 rs9322025 chr6:145729196 C/T cg23711669 chr6:146136114 FBXO30 0.62 5.63 0.45 1.14e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg01802117 chr1:53393560 SCP2 0.44 5.31 0.43 4.89e-7 Monocyte count; TGCT cis rs2742417 1.000 rs2249357 chr3:45758381 C/A cg04837898 chr3:45731254 SACM1L -0.51 -5.27 -0.43 5.85e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg09436375 chr6:42928200 GNMT -0.4 -5.16 -0.42 9.7e-7 Plasma homocysteine levels (post-methionine load test); TGCT cis rs6459804 0.588 rs78762416 chr7:157511142 G/A cg14168080 chr7:157504135 PTPRN2 -0.41 -4.86 -0.4 3.43e-6 Bipolar disorder and schizophrenia; TGCT cis rs7179456 0.547 rs653765 chr15:59042012 T/C cg05156742 chr15:59063176 FAM63B 0.51 5.01 0.41 1.8e-6 Asperger disorder; TGCT cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs60843830 0.661 rs7561648 chr2:105171 G/T cg25945732 chr2:264204 ACP1;SH3YL1 0.62 5.52 0.44 1.92e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs6582630 0.502 rs11520279 chr12:38360871 A/G cg26384229 chr12:38710491 ALG10B 0.79 6.98 0.53 1.61e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs9640161 0.663 rs1916932 chr7:150021644 T/C cg17279839 chr7:150038598 RARRES2 0.43 4.6 0.38 1.02e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs3008870 0.727 rs4582760 chr1:67464394 G/A cg08660285 chr1:67390436 MIER1;WDR78 -0.82 -8.51 -0.61 4.69e-14 Lymphocyte percentage of white cells; TGCT cis rs1322512 0.677 rs2695254 chr6:152926021 A/C cg03415253 chr6:152958462 SYNE1 -0.55 -5.25 -0.43 6.43e-7 Tonometry; TGCT cis rs858239 0.539 rs6976957 chr7:23187333 T/A cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs13082711 0.522 rs479302 chr3:27363033 A/G cg02860705 chr3:27208620 NA 0.29 4.71 0.39 6.43e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs13191362 1.000 rs35424047 chr6:163029715 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.18e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2455799 0.559 rs7629968 chr3:15915864 C/T cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg12310025 chr6:25882481 NA -0.66 -5.92 -0.47 3.01e-8 Intelligence (multi-trait analysis); TGCT cis rs155076 1.000 rs261404 chr13:21858162 T/G cg11317459 chr13:21872234 NA -1.39 -11.7 -0.72 9.04e-22 White matter hyperintensity burden; TGCT cis rs68170813 0.652 rs17482543 chr7:107169174 C/G cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs7267979 0.932 rs6115200 chr20:25487377 G/T cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs711830 0.965 rs2072590 chr2:177042633 A/C cg13092806 chr2:177043255 NA 0.78 6.27 0.49 5.46e-9 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg11494091 chr17:61959527 GH2 -0.42 -7.27 -0.55 3.52e-11 Height; TGCT cis rs35306767 0.903 rs12769873 chr10:936526 G/T cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs910316 0.783 rs11850751 chr14:75590113 A/T cg23033748 chr14:75592666 NEK9 0.29 4.9 0.4 2.95e-6 Height; TGCT cis rs116095464 0.614 rs10061564 chr5:271329 T/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT trans rs1814175 0.817 rs28525029 chr11:50045815 A/G cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs1163251 0.837 rs658442 chr1:120244858 T/G cg19096424 chr1:120255104 PHGDH 0.6 5.93 0.47 2.76e-8 Blood metabolite levels; TGCT cis rs669446 0.561 rs530201 chr1:44102257 T/C cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs889312 0.500 rs832552 chr5:56113850 A/C cg24531977 chr5:56204891 C5orf35 0.48 4.8 0.4 4.5e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs13082711 1.000 rs34234262 chr3:27539188 G/A cg02860705 chr3:27208620 NA 0.34 4.64 0.38 8.68e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs13427251 0.903 rs6746402 chr2:100150443 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.59 -5.52 -0.44 1.88e-7 Chronic sinus infection; TGCT cis rs4986172 0.734 rs60289499 chr17:43218677 G/A cg10701640 chr17:43249399 NA 0.53 6.38 0.5 3.15e-9 Height; TGCT cis rs2658782 0.951 rs72972357 chr11:93118840 T/C cg18152523 chr11:93063302 CCDC67 0.77 6.18 0.49 8.42e-9 Pulmonary function decline; TGCT cis rs2439831 0.867 rs16957627 chr15:43642657 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs9910055 0.762 rs6503489 chr17:42246289 G/A cg19774624 chr17:42201019 HDAC5 -0.83 -8.49 -0.61 5.19e-14 Total body bone mineral density; TGCT cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg23172400 chr8:95962367 TP53INP1 0.33 4.99 0.41 1.98e-6 Type 2 diabetes; TGCT cis rs7727544 0.735 rs272894 chr5:131662460 C/T cg14196790 chr5:131705035 SLC22A5 0.32 4.56 0.38 1.19e-5 Blood metabolite levels; TGCT cis rs2963155 0.518 rs174048 chr5:142650404 T/C cg17617527 chr5:142782415 NR3C1 0.86 6.49 0.5 1.82e-9 Breast cancer; TGCT cis rs17401966 0.931 rs2236678 chr1:10471789 A/T cg19773385 chr1:10388646 KIF1B -0.23 -5.42 -0.44 2.97e-7 Hepatocellular carcinoma; TGCT cis rs10883723 0.773 rs7917402 chr10:104246690 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs10089 0.953 rs1036171 chr5:127402798 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.73 6.81 0.52 3.74e-10 Ileal carcinoids; TGCT cis rs17076896 0.786 rs74034965 chr13:19928097 G/A cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs1691799 0.863 rs1168291 chr12:66732488 T/C cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs77948430 0.748 rs113823977 chr8:13151121 G/A cg25598624 chr8:12235727 FAM66A 0.32 4.69 0.39 6.97e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs1670533 0.932 rs2045067 chr4:1052355 C/T cg20887711 chr4:1340912 KIAA1530 0.72 5.71 0.46 7.8e-8 Recombination rate (females); TGCT cis rs2549003 1.000 rs2549004 chr5:131827825 C/G cg02551604 chr5:131831745 NA 0.9 11.87 0.73 3.59e-22 Asthma (sex interaction); TGCT cis rs1153858 0.725 rs74572151 chr15:45647526 T/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs806215 0.526 rs4728079 chr7:127480364 A/G cg11539674 chr7:127291444 SND1 -0.36 -4.67 -0.39 7.77e-6 Type 2 diabetes; TGCT trans rs1814175 0.791 rs10769593 chr11:49616217 T/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.57 -0.61 3.46e-14 Height; TGCT cis rs1472147 0.696 rs1532222 chr7:128516945 A/C cg00260937 chr7:128520193 KCP -0.43 -5.75 -0.46 6.46e-8 Calcium levels; TGCT trans rs1814175 0.645 rs847632 chr11:49926097 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs9902453 0.765 rs2628191 chr17:28051140 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.39 -0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs8014204 0.935 rs2853779 chr14:75368508 G/A cg06637938 chr14:75390232 RPS6KL1 -0.73 -6.94 -0.53 1.96e-10 Caffeine consumption; TGCT cis rs6570726 0.846 rs7762536 chr6:145923145 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.61 0.38 9.98e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.790 rs9403756 chr6:146257761 C/G cg05347473 chr6:146136440 FBXO30 -0.48 -4.71 -0.39 6.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg03188948 chr7:1209495 NA 0.46 6.1 0.48 1.24e-8 Longevity;Endometriosis; TGCT cis rs9467773 1.000 rs9467778 chr6:26534743 T/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs6429082 0.715 rs2131923 chr1:235580821 A/G cg26050004 chr1:235667680 B3GALNT2 -0.57 -5.03 -0.41 1.7e-6 Adiposity; TGCT cis rs6424115 0.545 rs11576333 chr1:24065770 C/T cg15997130 chr1:24165203 NA -0.66 -6.1 -0.48 1.24e-8 Immature fraction of reticulocytes; TGCT cis rs1018836 0.884 rs7008765 chr8:91632589 C/T cg16814680 chr8:91681699 NA -0.87 -9.49 -0.65 2.12e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9425766 0.640 rs1322774 chr1:173839240 C/T cg07177756 chr1:173836307 SNORD75;SNORD78;ZBTB37;SNORD76;GAS5;SNORD77;SNORD44 0.53 4.61 0.38 9.73e-6 Life satisfaction; TGCT cis rs9790314 1.000 rs6794601 chr3:160946769 C/T cg03342759 chr3:160939853 NMD3 -0.43 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs7572733 0.555 rs2342558 chr2:198920142 T/C cg00792783 chr2:198669748 PLCL1 0.59 5.15 0.42 1.01e-6 Dermatomyositis; TGCT cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg22029157 chr1:209979665 IRF6 0.76 6.24 0.49 6.3e-9 Cleft lip with or without cleft palate; TGCT cis rs1775715 0.835 rs113450267 chr10:32223728 G/A cg14930904 chr10:32216787 ARHGAP12 0.52 4.82 0.4 4.16e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs67460515 0.892 rs10513564 chr3:161059762 A/G cg03342759 chr3:160939853 NMD3 -0.52 -5.68 -0.45 9.16e-8 Parkinson's disease; TGCT cis rs2060793 0.741 rs4344519 chr11:14722893 G/C cg00085434 chr11:14927489 NA 0.34 4.68 0.39 7.45e-6 Vitamin D levels; TGCT cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg11890956 chr21:40555474 PSMG1 -0.72 -6.47 -0.5 2.07e-9 Cognitive function; TGCT trans rs4919669 0.720 rs729025 chr10:104342206 C/T cg24066601 chr6:26271455 HIST1H3G 0.66 6.81 0.52 3.7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs6988636 1.000 rs58177772 chr8:124188067 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs7100689 0.646 rs10736356 chr10:82148325 A/G cg01528321 chr10:82214614 TSPAN14 0.79 7.93 0.58 1.11e-12 Post bronchodilator FEV1; TGCT cis rs16865717 0.513 rs6431837 chr2:7036811 C/T cg20486407 chr2:7037101 RSAD2 -0.39 -5.11 -0.42 1.17e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs7223966 1.000 rs56057198 chr17:61733332 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.83 0.4 3.93e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs858239 0.600 rs7776644 chr7:23119307 C/T cg05602783 chr7:23145260 KLHL7 -0.61 -5.03 -0.41 1.68e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs11969893 0.850 rs9404055 chr6:101302260 C/T cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs2282802 0.685 rs12717951 chr5:139589309 A/G cg01081189 chr5:139537190 NA 0.29 5.41 0.44 3.19e-7 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.935 rs374000 chr6:145855290 C/T cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs66573146 1.000 rs28729690 chr4:6962061 C/T cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs4144743 0.938 rs55677902 chr17:45322572 G/T cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs72949976 0.564 rs4673730 chr2:214024836 G/T cg08319019 chr2:214017104 IKZF2 0.84 8.38 0.6 9.58e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs3096299 0.719 rs2911265 chr16:89511328 G/A cg02187348 chr16:89574699 SPG7 0.62 6.66 0.51 8.13e-10 Multiple myeloma (IgH translocation); TGCT cis rs7666738 0.606 rs13108868 chr4:99083753 C/T cg17366294 chr4:99064904 C4orf37 0.57 5.34 0.43 4.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7818688 0.697 rs3802192 chr8:95987471 C/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs763121 0.889 rs1837988 chr22:38901094 A/G cg06022373 chr22:39101656 GTPBP1 0.79 7.78 0.57 2.45e-12 Menopause (age at onset); TGCT cis rs6912958 0.559 rs451829 chr6:88041919 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.73 7.63 0.57 5.25e-12 Monocyte percentage of white cells; TGCT cis rs2580764 0.598 rs7340476 chr2:55227346 G/C cg09592903 chr2:55203963 RTN4 -0.24 -5.32 -0.43 4.73e-7 Mean platelet volume; TGCT cis rs2224391 0.590 rs2773298 chr6:5242067 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.12 -0.48 1.16e-8 Height; TGCT cis rs11190604 1.000 rs2489039 chr10:102328036 T/A cg16342193 chr10:102329863 NA -0.42 -5.39 -0.44 3.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7267979 1.000 rs7268053 chr20:25328286 A/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6693567 0.545 rs2275246 chr1:150460168 A/G cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Migraine; TGCT cis rs112217694 1.000 rs77617156 chr4:104648984 G/A cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs9457247 0.565 rs12193698 chr6:167512073 C/A cg07741184 chr6:167504864 NA 0.28 5.6 0.45 1.33e-7 Crohn's disease; TGCT cis rs17331151 0.573 rs77223362 chr3:52865125 G/A cg07884673 chr3:53033167 SFMBT1 0.49 5.66 0.45 1.01e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg22105103 chr4:187893119 NA 0.34 4.76 0.39 5.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4713118 0.619 rs200486 chr6:27779506 C/T cg10876282 chr6:28092338 ZSCAN16 0.58 4.9 0.4 2.98e-6 Parkinson's disease; TGCT cis rs1541995 1.000 rs35504206 chr15:96392333 G/C cg00882281 chr15:96346592 NA 0.29 4.68 0.39 7.42e-6 Photic sneeze reflex; TGCT cis rs2153535 0.563 rs1737586 chr6:8535897 C/T cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.56e-7 Motion sickness; TGCT cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2066819 1.000 rs2643626 chr12:56726518 C/T cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT cis rs7937682 0.883 rs549143 chr11:111463779 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs7100689 0.784 rs4934139 chr10:82177023 C/A cg01528321 chr10:82214614 TSPAN14 0.91 9.58 0.65 1.3e-16 Post bronchodilator FEV1; TGCT cis rs4704846 1.000 rs1036200 chr5:156531865 A/G cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs9291683 0.546 rs4529049 chr4:10045389 C/T cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Bone mineral density; TGCT cis rs4819052 0.807 rs4819047 chr21:46665139 C/T cg06618935 chr21:46677482 NA -0.37 -5.87 -0.47 3.72e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3008870 0.755 rs6657065 chr1:67384639 T/G cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.47 0.61 5.86e-14 Lymphocyte percentage of white cells; TGCT cis rs13394619 0.840 rs11674605 chr2:11722575 A/G cg07314298 chr2:11723111 GREB1 -0.3 -5.13 -0.42 1.09e-6 Endometriosis; TGCT cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg07061783 chr6:25882402 NA -0.56 -5.56 -0.45 1.55e-7 Intelligence (multi-trait analysis); TGCT cis rs1055129 0.560 rs2305913 chr17:73922941 T/C cg10935138 chr17:73851978 WBP2 0.54 4.71 0.39 6.44e-6 White matter hyperintensity burden; TGCT cis rs7027203 0.797 rs4744294 chr9:96612114 C/G cg13679303 chr9:96623674 NA -0.66 -10.76 -0.69 1.84e-19 DNA methylation (variation); TGCT cis rs11122272 0.638 rs2739514 chr1:231514806 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -6.83 -0.52 3.3e-10 Hemoglobin concentration; TGCT cis rs478304 0.627 rs11604568 chr11:65511336 G/A cg10518572 chr11:65560635 OVOL1 -0.23 -4.52 -0.38 1.42e-5 Acne (severe); TGCT cis rs7681440 0.669 rs7693616 chr4:90792230 G/T cg20003494 chr4:90757398 SNCA 0.51 4.48 0.37 1.69e-5 Dementia with Lewy bodies; TGCT cis rs9677476 0.657 rs7604042 chr2:232135541 A/T cg07929768 chr2:232055508 NA 0.28 4.48 0.37 1.65e-5 Food antigen IgG levels; TGCT cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.3 0.49 4.63e-9 Cognitive function; TGCT cis rs7760949 0.963 rs7453814 chr6:13918291 C/G cg27413430 chr6:13925136 RNF182 0.62 5.79 0.46 5.31e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs9814567 1.000 rs1880376 chr3:134270347 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs523522 0.926 rs10849766 chr12:121025894 G/A cg27279351 chr12:120934652 DYNLL1 0.72 6.05 0.48 1.62e-8 High light scatter reticulocyte count; TGCT cis rs9858542 0.953 rs11926781 chr3:49603289 C/T cg03060546 chr3:49711283 APEH -0.63 -5.48 -0.44 2.28e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7809950 1.000 rs2712201 chr7:107145564 T/C cg23024343 chr7:107201750 COG5 -0.35 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs295140 1.000 rs13005573 chr2:201164696 G/C cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs6770219 0.516 rs7650292 chr3:186166085 T/C cg15503553 chr3:185216877 TMEM41A 0.63 4.78 0.39 4.88e-6 Cerebrospinal T-tau levels; TGCT cis rs9457247 1.000 rs9457247 chr6:167392174 C/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg10802521 chr3:52805072 NEK4 -0.7 -8.67 -0.61 2.04e-14 Bipolar disorder; TGCT cis rs4727027 0.870 rs62507512 chr7:148799338 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.68 0.39 7.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7223966 1.000 rs15637 chr17:61772050 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 5.17 0.42 8.94e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs73058052 0.867 rs57940349 chr19:50097607 C/T cg09250473 chr19:50168907 IRF3;BCL2L12 0.88 6.61 0.51 1.01e-9 Fibrinogen levels; TGCT cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.65 6.31 0.49 4.45e-9 Bipolar disorder; TGCT cis rs12220898 0.749 rs7913851 chr10:50482996 C/G cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs2760061 0.598 rs658238 chr1:228121291 A/G cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs3733585 0.673 rs10018204 chr4:9964570 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs9357506 1.000 rs1372569 chr6:46305542 G/A cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.37e-7 Body mass index; TGCT cis rs775227 0.574 rs16860849 chr3:113049993 C/T cg18753928 chr3:113234510 CCDC52 0.65 4.61 0.38 9.88e-6 Dental caries; TGCT cis rs10838634 1.000 rs7111760 chr11:46828273 T/C cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs1862618 0.671 rs2591965 chr5:56236176 T/C cg20203395 chr5:56204925 C5orf35 0.53 4.92 0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs3617 0.625 rs2245647 chr3:52862753 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.6 -0.38 1.02e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg07507251 chr3:52567010 NT5DC2 0.49 6.71 0.52 6.33e-10 Bipolar disorder; TGCT cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.15e-6 Blood metabolite levels; TGCT cis rs4689388 0.890 rs4688989 chr4:6290594 T/C cg00701064 chr4:6280414 WFS1 0.39 5.03 0.41 1.68e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7226408 0.802 rs55889065 chr18:34425307 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.83 0.4 4.02e-6 Obesity-related traits; TGCT cis rs912057 0.585 rs1745341 chr6:6744990 T/C cg06612196 chr6:6737390 NA 0.47 6.77 0.52 4.57e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs7940866 0.804 rs10894287 chr11:130808483 C/T cg05962950 chr11:130786565 SNX19 0.67 6.8 0.52 3.99e-10 Schizophrenia; TGCT cis rs2050392 0.771 rs303446 chr10:30728489 C/T cg18806716 chr10:30721971 MAP3K8 -0.51 -6.0 -0.47 2.05e-8 Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs13113899 chr4:99050422 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs916888 0.610 rs142167 chr17:44795234 C/T cg01341218 chr17:43662625 NA -0.85 -7.57 -0.56 7.46e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg07507251 chr3:52567010 NT5DC2 0.46 6.68 0.51 7.37e-10 Bipolar disorder; TGCT cis rs4319547 0.774 rs10773394 chr12:123124778 C/A cg05707623 chr12:122985044 ZCCHC8 -0.59 -4.95 -0.41 2.42e-6 Body mass index; TGCT cis rs6430585 0.527 rs62168830 chr2:136443900 A/T cg07169764 chr2:136633963 MCM6 1.0 9.14 0.63 1.51e-15 Corneal structure; TGCT cis rs9640161 0.750 rs17173617 chr7:150038023 G/C cg10018233 chr7:150070692 REPIN1 0.32 4.62 0.38 9.29e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs250677 0.687 rs250674 chr5:148438597 A/G cg23229984 chr5:148520753 ABLIM3 -0.2 -4.87 -0.4 3.26e-6 Breast cancer; TGCT cis rs751728 1.000 rs747695 chr6:33736672 G/A cg13859433 chr6:33739653 LEMD2 -0.4 -7.55 -0.56 8.33e-12 Crohn's disease; TGCT trans rs7618501 1.000 rs35261599 chr3:49773236 G/A cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2485376 0.842 rs11593146 chr10:104184981 A/G cg26089160 chr10:104170217 PSD 0.51 5.04 0.41 1.62e-6 QT interval; TGCT trans rs1814175 0.791 rs1722011 chr11:49899340 G/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.02 -0.58 6.85e-13 Height; TGCT cis rs600231 0.665 rs1784859 chr11:65220749 A/G cg11802864 chr11:65308245 LTBP3 -0.46 -4.55 -0.38 1.24e-5 Bone mineral density; TGCT cis rs11105298 0.891 rs4842662 chr12:89933446 T/C cg00757033 chr12:89920650 WDR51B 0.29 4.6 0.38 1.01e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9393777 0.513 rs1104871 chr6:26665235 T/G cg15659132 chr6:26577336 NA -0.73 -5.25 -0.43 6.5e-7 Intelligence (multi-trait analysis); TGCT cis rs6714788 0.546 rs12712062 chr2:100654307 A/T cg22139774 chr2:100720529 AFF3 -0.41 -6.5 -0.5 1.74e-9 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg02073558 chr3:44770973 ZNF501 0.73 7.37 0.55 2.08e-11 Depressive symptoms; TGCT cis rs8180040 0.966 rs2062278 chr3:47416761 C/T cg27129171 chr3:47204927 SETD2 0.65 7.67 0.57 4.29e-12 Colorectal cancer; TGCT cis rs8002180 0.959 rs8001475 chr13:95922407 T/C cg24476569 chr13:95954382 ABCC4 0.41 5.07 0.41 1.42e-6 Blood metabolite levels; TGCT trans rs1496653 0.602 rs71322189 chr3:23481899 A/C cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs208515 0.560 rs207084 chr6:66776966 T/C cg07460842 chr6:66804631 NA -1.06 -15.57 -0.81 5.81e-31 Exhaled nitric oxide levels; TGCT cis rs12134245 0.747 rs11164912 chr1:92005191 A/T cg07090678 chr1:91966139 CDC7 0.36 4.96 0.41 2.25e-6 Breast cancer; TGCT cis rs765787 0.530 rs3759895 chr15:45543870 G/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.49 -0.44 2.13e-7 Uric acid levels; TGCT cis rs4689592 0.554 rs66925245 chr4:7071999 C/T cg26116260 chr4:7069785 GRPEL1 -0.97 -7.88 -0.58 1.4e-12 Monocyte percentage of white cells; TGCT cis rs1008375 0.966 rs758483 chr4:17703614 G/T cg10189774 chr4:17578691 LAP3 -0.57 -4.85 -0.4 3.7e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2762353 0.904 rs13197601 chr6:25785935 G/A cg03517284 chr6:25882590 NA 0.51 5.33 0.43 4.47e-7 Blood metabolite levels; TGCT cis rs9583531 0.600 rs6492305 chr13:111361400 C/T cg24331049 chr13:111365604 ING1 0.76 7.31 0.55 2.95e-11 Coronary artery disease; TGCT cis rs7918232 0.825 rs4749233 chr10:27467967 G/A cg14442939 chr10:27389572 ANKRD26 0.82 5.75 0.46 6.69e-8 Breast cancer; TGCT cis rs416603 0.967 rs11640138 chr16:11362729 A/G cg00044050 chr16:11439710 C16orf75 0.8 8.05 0.59 5.64e-13 Type 1 diabetes; TGCT cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg21724239 chr8:58056113 NA 0.41 4.87 0.4 3.33e-6 Developmental language disorder (linguistic errors); TGCT cis rs911263 0.603 rs2180770 chr14:68773353 G/A cg18825221 chr14:68749962 RAD51L1 0.22 4.44 0.37 1.97e-5 Primary biliary cholangitis; TGCT cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs9393777 0.513 rs926300 chr6:27059443 A/T cg16898833 chr6:26189333 HIST1H4D 0.8 4.85 0.4 3.57e-6 Intelligence (multi-trait analysis); TGCT trans rs2469997 1.000 rs2470024 chr8:120363181 C/A cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs8062405 0.754 rs28410083 chr16:28631360 A/T cg09754948 chr16:28834200 ATXN2L -0.59 -4.78 -0.39 4.82e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs3092073 0.617 rs17448680 chr20:44594726 T/C cg23252815 chr20:44420276 WFDC3;DNTTIP1 -0.27 -4.44 -0.37 1.93e-5 Intelligence (multi-trait analysis); TGCT cis rs10489525 0.556 rs11102882 chr1:115612222 T/A cg12756093 chr1:115239321 AMPD1 -0.33 -4.5 -0.37 1.52e-5 Autism; TGCT cis rs858239 0.508 rs7805085 chr7:23190243 C/T cg05602783 chr7:23145260 KLHL7 -0.68 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg23172400 chr8:95962367 TP53INP1 -0.38 -6.38 -0.5 3.13e-9 Type 2 diabetes; TGCT cis rs13191362 1.000 rs35092540 chr6:163090778 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.9 0.66 2.27e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4072705 0.614 rs7020027 chr9:127241414 G/A cg13476313 chr9:127244764 NR5A1 -0.29 -4.81 -0.4 4.35e-6 Menarche (age at onset); TGCT cis rs6964587 0.620 rs6967588 chr7:91643402 G/T cg17063962 chr7:91808500 NA 0.75 7.1 0.54 8.68e-11 Breast cancer; TGCT cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg18402987 chr7:1209562 NA 0.76 6.26 0.49 5.67e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs919433 0.617 rs700645 chr2:198605514 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.01 0.41 1.84e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs7586879 0.639 rs6545776 chr2:25099357 A/C cg01884057 chr2:25150051 NA 0.33 6.3 0.49 4.82e-9 Body mass index; TGCT cis rs2963155 0.518 rs2963151 chr5:142734151 T/C cg17617527 chr5:142782415 NR3C1 0.81 6.3 0.49 4.84e-9 Breast cancer; TGCT cis rs8177179 0.967 rs6782434 chr3:133438834 C/G cg16262614 chr3:133464971 TF 0.35 4.72 0.39 6.28e-6 Iron status biomarkers (transferrin levels); TGCT cis rs763014 0.865 rs8909 chr16:633851 T/C cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs11711311 0.955 rs1048892 chr3:113464859 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs929354 0.739 rs1182439 chr7:157027367 G/A cg05182265 chr7:156933206 UBE3C 0.4 9.05 0.63 2.54e-15 Body mass index; TGCT cis rs75059851 0.756 rs56241440 chr11:133840830 A/C cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg11644478 chr21:40555479 PSMG1 1.02 11.16 0.71 1.86e-20 Cognitive function; TGCT cis rs3784262 0.669 rs4646580 chr15:58329211 A/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.28 -0.49 5.31e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs597539 0.731 rs664229 chr11:68624483 C/G cg21862992 chr11:68658383 NA 0.49 6.65 0.51 8.54e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs453301 0.686 rs28482034 chr8:8869664 G/A cg11995313 chr8:8860691 ERI1 0.51 4.46 0.37 1.84e-5 Joint mobility (Beighton score); TGCT cis rs7727544 0.571 rs12521097 chr5:131575338 G/A cg24060327 chr5:131705240 SLC22A5 -0.56 -5.37 -0.43 3.7e-7 Blood metabolite levels; TGCT cis rs6450176 0.830 rs7718193 chr5:53291591 T/G ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2842992 0.724 rs2273823 chr6:160211485 T/C cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg03760483 chr17:6899297 ALOX12 0.47 5.34 0.43 4.2e-7 Tonsillectomy; TGCT trans rs561341 0.883 rs7219239 chr17:30212016 A/G cg20587970 chr11:113659929 NA 0.8 9.3 0.64 6.34e-16 Hip circumference adjusted for BMI; TGCT cis rs1218582 0.772 rs4845688 chr1:154884142 T/C cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs9858542 0.953 rs7648841 chr3:49416825 G/A cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1371867 0.846 rs1660332 chr8:101309490 A/G cg00191853 chr8:101177733 SPAG1 0.23 4.76 0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs11711311 0.955 rs9851812 chr3:113412362 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.75 -6.84 -0.52 3.21e-10 IgG glycosylation; TGCT cis rs3784262 0.904 rs3784260 chr15:58253269 T/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.57 -0.56 7.27e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6840360 0.582 rs2724555 chr4:152341878 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.38 -0.5 3.17e-9 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs557625 chr11:68634722 G/A cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2456568 0.867 rs2511375 chr11:93671117 T/G cg17595323 chr11:93583763 C11orf90 -0.46 -5.86 -0.47 3.88e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs40363 0.645 rs250629 chr16:3525431 C/A cg00484396 chr16:3507460 NAT15 0.41 6.19 0.49 8.06e-9 Tuberculosis; TGCT cis rs10540 0.908 rs71487293 chr11:486414 G/A cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs7772486 0.790 rs9386141 chr6:146268623 T/A cg23711669 chr6:146136114 FBXO30 -0.85 -9.7 -0.66 6.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.897 rs3945 chr21:40566067 A/G cg11644478 chr21:40555479 PSMG1 0.96 9.75 0.66 5.14e-17 Cognitive function; TGCT cis rs7412746 0.658 rs1546376 chr1:150937661 A/G cg04414720 chr1:150670196 GOLPH3L 0.38 4.5 0.37 1.52e-5 Melanoma; TGCT cis rs17270561 0.779 rs17271767 chr6:25886921 C/T cg17042849 chr6:26104293 HIST1H4C -0.78 -5.52 -0.44 1.92e-7 Iron status biomarkers; TGCT cis rs7772486 0.764 rs7745696 chr6:146162829 T/C cg23711669 chr6:146136114 FBXO30 0.92 10.44 0.68 1.06e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs12410462 0.579 rs78343168 chr1:227621090 G/A cg23173402 chr1:227635558 NA 0.65 4.49 0.37 1.61e-5 Major depressive disorder; TGCT cis rs7412746 0.658 rs59988025 chr1:150940358 C/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.54 0.38 1.3e-5 Melanoma; TGCT cis rs12681287 0.640 rs13256765 chr8:87457833 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs155076 0.938 rs9509633 chr13:21844482 G/C cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs72781680 1.000 rs72781679 chr2:24237712 G/A cg08917208 chr2:24149416 ATAD2B 0.83 5.08 0.42 1.35e-6 Lymphocyte counts; TGCT cis rs11690935 0.959 rs10207085 chr2:172585885 T/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs17473412 1.000 rs75449813 chr5:122730653 C/G cg15125798 chr5:122621645 NA -0.6 -5.23 -0.43 7.01e-7 Total body bone mineral density; TGCT cis rs6981523 0.553 rs11989369 chr8:11055385 A/G cg21775007 chr8:11205619 TDH 0.5 4.61 0.38 1e-5 Neuroticism; TGCT cis rs7772486 0.720 rs991507 chr6:146023609 G/A cg13319975 chr6:146136371 FBXO30 0.53 4.8 0.4 4.49e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9325144 0.647 rs7980932 chr12:38921583 G/T cg26384229 chr12:38710491 ALG10B -0.56 -5.02 -0.41 1.76e-6 Morning vs. evening chronotype; TGCT cis rs6074578 0.679 rs13043289 chr20:137114 A/G cg16931068 chr20:139680 DEFB127 0.27 4.8 0.4 4.52e-6 Hirschsprung disease; TGCT cis rs62380364 0.774 rs2362108 chr5:88147771 G/A cg22951263 chr5:87985283 NA -0.48 -4.62 -0.38 9.39e-6 Intelligence (multi-trait analysis); TGCT cis rs11673344 0.523 rs2385415 chr19:37526193 G/A cg08039142 chr19:36980659 ZNF566 0.5 4.64 0.38 8.58e-6 Obesity-related traits; TGCT cis rs2832191 1.000 rs2832185 chr21:30483761 C/G cg24692254 chr21:30365293 RNF160 -0.83 -8.72 -0.62 1.56e-14 Dental caries; TGCT cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9814567 1.000 rs9864346 chr3:134312352 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7843479 0.601 rs11785043 chr8:21810377 C/T cg17168535 chr8:21777572 XPO7 0.81 8.33 0.6 1.25e-13 Mean corpuscular volume; TGCT cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg20607798 chr8:58055168 NA 0.56 4.7 0.39 6.67e-6 Developmental language disorder (linguistic errors); TGCT cis rs11676348 0.818 rs7425447 chr2:218980183 T/C cg00012203 chr2:219082015 ARPC2 -0.51 -4.8 -0.4 4.39e-6 Ulcerative colitis; TGCT cis rs12048904 0.964 rs12027668 chr1:101330984 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.55 5.14 0.42 1.04e-6 Multiple sclerosis; TGCT cis rs2251381 0.750 rs2251186 chr21:30528880 G/A cg08807101 chr21:30365312 RNF160 0.51 4.49 0.37 1.63e-5 Selective IgA deficiency; TGCT cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs6909430 0.539 rs13196732 chr6:98799148 A/G cg20000812 chr6:99276697 NA -0.51 -4.46 -0.37 1.79e-5 Quantitative traits; TGCT cis rs637571 0.522 rs28578718 chr11:65748400 C/A cg17985854 chr11:65770987 BANF1;EIF1AD 0.22 4.54 0.38 1.32e-5 Eosinophil percentage of white cells; TGCT cis rs7552404 0.731 rs931507 chr1:76401577 G/A cg22875332 chr1:76189707 ACADM -0.66 -6.78 -0.52 4.38e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12477438 0.520 rs13012481 chr2:99754290 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 12.89 0.76 1.24e-24 Chronic sinus infection; TGCT cis rs1670533 0.932 rs13137819 chr4:1042115 T/C cg20887711 chr4:1340912 KIAA1530 0.71 5.16 0.42 9.34e-7 Recombination rate (females); TGCT cis rs1865760 0.865 rs9393677 chr6:25945815 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT cis rs2832191 0.791 rs28633762 chr21:30500070 C/T cg24692254 chr21:30365293 RNF160 -0.86 -9.11 -0.63 1.83e-15 Dental caries; TGCT cis rs951366 0.966 rs11240565 chr1:205722958 C/T cg07157834 chr1:205819609 PM20D1 -0.33 -4.72 -0.39 6.19e-6 Menarche (age at onset); TGCT cis rs1784581 0.651 rs1784588 chr6:162390027 T/A cg17173639 chr6:162384350 PARK2 -0.47 -8.16 -0.59 3.15e-13 Itch intensity from mosquito bite; TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg24675658 chr1:53192096 ZYG11B -0.69 -7.86 -0.58 1.55e-12 Monocyte count; TGCT cis rs1395 0.744 rs1122227 chr2:27544285 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.6 7.62 0.56 5.61e-12 Blood metabolite levels; TGCT cis rs7772486 0.754 rs6570708 chr6:145989428 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.77 -0.39 5.07e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs17376456 0.877 rs10072592 chr5:93405989 C/G cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs2997447 0.846 rs3008225 chr1:26390181 T/A cg19633962 chr1:26362018 EXTL1 -0.68 -4.62 -0.38 9.47e-6 QRS complex (12-leadsum); TGCT cis rs10791097 0.720 rs6590518 chr11:130733530 C/T cg14779329 chr11:130786720 SNX19 0.28 4.78 0.39 4.88e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1691799 0.899 rs1168304 chr12:66738667 A/C cg16791601 chr12:66731901 HELB -0.28 -6.1 -0.48 1.25e-8 White blood cell count (basophil); TGCT cis rs6088590 0.561 rs6088527 chr20:33155841 C/T cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs733175 0.857 rs7666545 chr4:10012372 C/T cg11266682 chr4:10021025 SLC2A9 0.52 4.68 0.39 7.48e-6 Psychosis and Alzheimer's disease; TGCT cis rs614226 1.000 rs12310837 chr12:120880572 C/T cg10072921 chr12:121022843 NA -0.42 -4.47 -0.37 1.77e-5 Type 1 diabetes nephropathy; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg09033563 chr22:24373618 LOC391322 -0.48 -4.63 -0.38 8.97e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1005277 0.540 rs2145487 chr10:38010077 A/G cg25427524 chr10:38739819 LOC399744 -0.33 -6.6 -0.51 1.07e-9 Extrinsic epigenetic age acceleration; TGCT cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg20637647 chr7:64974828 NA -0.9 -5.06 -0.41 1.45e-6 Diabetic kidney disease; TGCT cis rs9914544 1.000 rs6502677 chr17:18803658 A/G cg26306683 chr17:18585705 ZNF286B 0.54 4.82 0.4 4.11e-6 Educational attainment (years of education); TGCT trans rs2727020 0.617 rs7102702 chr11:49401125 T/G cg03929089 chr4:120376271 NA -0.68 -7.23 -0.54 4.35e-11 Coronary artery disease; TGCT cis rs12216125 0.549 rs9358905 chr6:26077839 T/A cg16482183 chr6:26056742 HIST1H1C 0.57 4.99 0.41 1.96e-6 Iron status biomarkers; TGCT cis rs2640806 0.505 rs7837495 chr8:97359508 T/C cg04026948 chr8:97953330 PGCP -0.26 -4.64 -0.38 8.63e-6 Obesity-related traits; TGCT cis rs6964587 1.000 rs6952389 chr7:91657994 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs11696501 0.688 rs6073854 chr20:44309605 A/G cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs4499344 0.730 rs7250272 chr19:33100338 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs11190604 1.000 rs11190589 chr10:102275471 A/G cg23241863 chr10:102295624 HIF1AN 0.7 5.39 0.44 3.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs922182 0.569 rs6494457 chr15:64263532 C/A cg02919090 chr15:64263738 DAPK2 0.36 6.87 0.53 2.76e-10 Blood protein levels; TGCT cis rs67311347 0.544 rs4974047 chr3:40339653 G/T cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs3806933 0.522 rs13153937 chr5:110434307 C/T cg04022379 chr5:110408740 TSLP 0.61 6.35 0.5 3.79e-9 Eosinophilic esophagitis; TGCT cis rs7666738 0.830 rs7659006 chr4:98934529 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6490294 0.851 rs1016079 chr12:112410186 G/T cg10833066 chr12:111807467 FAM109A -0.37 -5.53 -0.44 1.79e-7 Mean platelet volume; TGCT cis rs12136530 0.577 rs12120180 chr1:19791441 C/T cg18923740 chr1:19971790 NBL1 0.45 4.9 0.4 2.91e-6 Lead levels in blood; TGCT cis rs4822044 0.617 rs13054514 chr22:42130383 A/G cg06481639 chr22:41940642 POLR3H 0.54 4.57 0.38 1.17e-5 Cannabis dependence symptom count; TGCT cis rs11098499 0.954 rs28572238 chr4:120316686 T/G cg09307838 chr4:120376055 NA 0.68 6.7 0.52 6.46e-10 Corneal astigmatism; TGCT cis rs6456156 0.586 rs4710176 chr6:167491639 T/C cg07741184 chr6:167504864 NA 0.24 4.72 0.39 6.21e-6 Primary biliary cholangitis; TGCT cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg21724239 chr8:58056113 NA 0.45 5.26 0.43 6.08e-7 Developmental language disorder (linguistic errors); TGCT cis rs2777491 0.574 rs316616 chr15:41746276 G/A cg18705301 chr15:41695430 NDUFAF1 -0.94 -17.35 -0.84 5.64e-35 Ulcerative colitis; TGCT cis rs2204008 0.744 rs11519905 chr12:38222959 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.38 0.55 2e-11 Bladder cancer; TGCT cis rs2836950 0.565 rs7276046 chr21:40581293 T/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.6 -0.38 1.04e-5 Menarche (age at onset); TGCT cis rs3806843 0.576 rs246072 chr5:140320426 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.42 -5.37 -0.43 3.69e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs3796352 1.000 rs11713206 chr3:52999243 A/G cg07884673 chr3:53033167 SFMBT1 0.63 5.74 0.46 6.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7829975 0.593 rs2921077 chr8:8304502 C/T cg08975724 chr8:8085496 FLJ10661 0.59 5.74 0.46 7.01e-8 Mood instability; TGCT cis rs17125944 0.505 rs80211268 chr14:53265483 C/G cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs9650657 0.737 rs4551304 chr8:10665069 A/G cg27411982 chr8:10470053 RP1L1 -0.23 -5.17 -0.42 9.17e-7 Neuroticism; TGCT cis rs11098499 1.000 rs6837898 chr4:120179154 C/T cg09307838 chr4:120376055 NA 0.49 4.48 0.37 1.67e-5 Corneal astigmatism; TGCT cis rs12681288 0.550 rs12675410 chr8:957845 T/C cg04851639 chr8:1020857 NA -0.27 -4.45 -0.37 1.85e-5 Schizophrenia; TGCT cis rs992157 0.735 rs13392177 chr2:219112956 C/T cg00012203 chr2:219082015 ARPC2 -0.81 -10.28 -0.68 2.67e-18 Colorectal cancer; TGCT cis rs527409 1.000 rs12083021 chr1:58712791 A/T cg26345888 chr1:58716257 DAB1 0.81 4.51 0.38 1.51e-5 Kawasaki disease; TGCT cis rs1008375 0.902 rs6844984 chr4:17651304 C/G cg16339924 chr4:17578868 LAP3 0.63 5.26 0.43 6.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9300255 0.569 rs1790115 chr12:123620270 C/G cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs7208859 0.673 rs1347359 chr17:28914529 T/C cg04154034 chr17:28927549 LRRC37B2 0.8 4.99 0.41 1.99e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3751972 0.911 rs9630740 chr17:26242756 C/G cg02948944 chr17:26242737 NA 0.51 7.32 0.55 2.78e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs25422 0.887 rs9320666 chr6:118989181 C/T cg07617317 chr6:118971624 C6orf204 0.45 5.1 0.42 1.26e-6 Renal cell carcinoma; TGCT trans rs210152 0.531 rs4713634 chr6:33514708 T/C cg08795360 chr21:41033440 B3GALT5 -0.43 -6.64 -0.51 8.94e-10 Schizophrenia; TGCT cis rs77106637 1.000 rs11600585 chr11:72727840 A/G cg03713592 chr11:72463424 ARAP1 0.83 5.49 0.44 2.12e-7 Type 2 diabetes; TGCT cis rs2050392 1.000 rs7077496 chr10:30692028 G/A cg18806716 chr10:30721971 MAP3K8 0.48 6.0 0.47 2.05e-8 Inflammatory bowel disease; TGCT cis rs2933343 0.729 rs1680786 chr3:128644840 T/C cg11901034 chr3:128598214 ACAD9 -0.65 -6.05 -0.48 1.55e-8 IgG glycosylation; TGCT cis rs12220898 0.526 rs4838505 chr10:50556797 T/C cg06072769 chr10:50146962 WDFY4 0.32 4.65 0.39 8.38e-6 Inflammatory biomarkers; TGCT cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs765787 0.530 rs2413780 chr15:45538866 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs7829975 0.535 rs4841005 chr8:8501230 A/G cg06636001 chr8:8085503 FLJ10661 -0.51 -4.74 -0.39 5.79e-6 Mood instability; TGCT cis rs2832191 0.791 rs4817270 chr21:30480368 G/A cg24692254 chr21:30365293 RNF160 -0.95 -10.52 -0.69 7.06e-19 Dental caries; TGCT cis rs7095607 0.721 rs10997950 chr10:69912278 G/A cg18986048 chr10:69913749 MYPN 0.47 5.38 0.43 3.64e-7 Lung function (FVC); TGCT cis rs79349575 0.594 rs62078375 chr17:47034974 A/G cg07967210 chr17:47022446 SNF8 0.43 5.88 0.47 3.51e-8 Type 2 diabetes; TGCT cis rs79057730 0.599 rs4721086 chr7:821123 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.65 6.12 0.48 1.14e-8 Initial pursuit acceleration; TGCT cis rs1215050 0.567 rs4699317 chr4:98602032 G/A cg05340658 chr4:99064831 C4orf37 -0.38 -4.49 -0.37 1.59e-5 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs1496653 0.602 rs115867975 chr3:23346046 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs9436747 0.641 rs10443259 chr1:66051350 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.04 0.41 1.59e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs3947 1.000 rs1736083 chr8:11703497 G/T cg02840367 chr8:11660030 FDFT1 0.91 6.66 0.51 7.98e-10 Blood protein levels; TGCT cis rs9399135 0.967 rs12527707 chr6:135324511 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg19635926 chr16:89946313 TCF25 0.27 4.6 0.38 1.02e-5 Skin colour saturation; TGCT cis rs752010 0.574 rs6671999 chr1:42120416 G/A cg06885757 chr1:42089581 HIVEP3 0.24 4.56 0.38 1.21e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs2235642 0.750 rs763152 chr16:1658056 T/C cg07639376 chr16:1584516 IFT140;TMEM204 -0.29 -4.95 -0.41 2.38e-6 Coronary artery disease; TGCT cis rs12908161 1.000 rs34900908 chr15:85257599 G/A cg11189052 chr15:85197271 WDR73 0.75 6.29 0.49 5.02e-9 Schizophrenia; TGCT cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs826838 0.967 rs1719852 chr12:39128531 A/G cg13010199 chr12:38710504 ALG10B -0.59 -4.66 -0.39 8.16e-6 Heart rate; TGCT trans rs1814175 0.817 rs3974439 chr11:50022607 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT trans rs6052484 0.602 rs6076649 chr20:4258071 A/G cg25044834 chr11:68177524 LRP5 0.32 6.87 0.53 2.7e-10 Sense of smell; TGCT trans rs797680 0.927 rs1000607 chr1:93772001 T/C cg27528825 chr2:159282178 CCDC148 -0.34 -6.71 -0.52 6.19e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT cis rs9467773 1.000 rs4713006 chr6:26519872 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs7819412 0.774 rs34208825 chr8:11014616 T/G cg21775007 chr8:11205619 TDH -0.55 -4.92 -0.4 2.71e-6 Triglycerides; TGCT cis rs5771225 0.505 rs5771111 chr22:50695946 C/G cg16473166 chr22:50639996 SELO 0.69 5.69 0.45 8.74e-8 Late-onset Alzheimer's disease; TGCT cis rs739496 0.895 rs7965040 chr12:111920295 A/C cg10833066 chr12:111807467 FAM109A 0.37 5.39 0.44 3.49e-7 Platelet count; TGCT cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs868036 0.718 rs28463100 chr15:68078769 T/C cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs3820928 1.000 rs3731593 chr2:227773924 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.64 -0.38 8.58e-6 Pulmonary function; TGCT cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg26818010 chr10:134567672 INPP5A -0.38 -5.19 -0.42 8.5e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs8078723 1.000 rs709592 chr17:38175553 C/T cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs3947 1.000 rs709821 chr8:11702594 G/C cg02840367 chr8:11660030 FDFT1 0.91 6.7 0.52 6.58e-10 Blood protein levels; TGCT cis rs12428086 1.000 rs17181551 chr13:36436924 T/C cg09072216 chr13:36919344 SPG20 0.27 4.5 0.37 1.56e-5 Obesity-related traits; TGCT cis rs231513 1.000 rs231513 chr17:41965200 C/G cg26893861 chr17:41843967 DUSP3 -0.74 -5.21 -0.42 7.52e-7 Cognitive function; TGCT cis rs546131 0.642 rs7946980 chr11:34820438 C/T cg06937548 chr11:34938143 PDHX;APIP 0.57 5.0 0.41 1.87e-6 Lung disease severity in cystic fibrosis; TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg06634786 chr22:41940651 POLR3H -0.83 -7.9 -0.58 1.31e-12 Vitiligo; TGCT cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg26118208 chr10:134322334 NA 0.25 4.65 0.39 8.37e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs231513 0.906 rs11657681 chr17:42005363 G/A cg26893861 chr17:41843967 DUSP3 0.73 5.1 0.42 1.25e-6 Cognitive function; TGCT cis rs854765 0.547 rs4643387 chr17:17972973 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.81 8.63 0.61 2.42e-14 Total body bone mineral density; TGCT cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs7552404 0.960 rs12085123 chr1:76149749 G/A cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4783244 0.897 rs4597315 chr16:82652931 T/C cg09415485 chr16:82663111 CDH13 -0.25 -4.66 -0.39 7.97e-6 Adiponectin levels; TGCT cis rs3099143 1.000 rs3099143 chr15:77104856 A/C cg21673338 chr15:77095150 SCAPER -0.52 -4.87 -0.4 3.28e-6 Recalcitrant atopic dermatitis; TGCT cis rs56104184 0.779 rs4802513 chr19:49357656 T/A cg15549821 chr19:49342101 PLEKHA4 -0.76 -8.76 -0.62 1.2e-14 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4555082 1.000 rs4277291 chr14:105759009 A/G cg10792982 chr14:105748885 BRF1 0.22 4.48 0.37 1.7e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs6866344 0.601 rs12187838 chr5:178099833 T/C cg10224037 chr5:178157518 ZNF354A 0.63 5.36 0.43 3.93e-7 Neutrophil percentage of white cells; TGCT trans rs7618501 1.000 rs1491986 chr3:49739086 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs66887589 0.592 rs62320740 chr4:120279486 C/A cg09307838 chr4:120376055 NA 0.46 4.59 0.38 1.09e-5 Diastolic blood pressure; TGCT cis rs453301 0.571 rs2929305 chr8:9085217 G/A cg15556689 chr8:8085844 FLJ10661 -0.64 -6.05 -0.48 1.6e-8 Joint mobility (Beighton score); TGCT cis rs986417 1.000 rs8021348 chr14:60952777 G/T cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs208520 0.690 rs12204512 chr6:66710486 C/T cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs4820792 0.725 rs5752777 chr22:29110002 T/C cg03733026 chr22:29445468 ZNRF3 0.25 4.85 0.4 3.67e-6 Breast size; TGCT cis rs4808199 0.895 rs10421505 chr19:19459554 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.65 4.91 0.4 2.77e-6 Nonalcoholic fatty liver disease; TGCT cis rs477895 0.713 rs1059440 chr11:63991801 C/T cg23719950 chr11:63933701 MACROD1 0.71 5.86 0.47 3.99e-8 Mean platelet volume; TGCT cis rs7726839 0.574 rs72707007 chr5:661856 T/C cg20362242 chr5:692897 TPPP 0.51 4.7 0.39 6.92e-6 Obesity-related traits; TGCT cis rs2302045 1.000 rs6732666 chr2:242055918 G/A cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs2354432 0.607 rs894469 chr1:146672906 C/T cg25205988 chr1:146714368 CHD1L 1.33 6.35 0.5 3.68e-9 Mitochondrial DNA levels; TGCT cis rs4808199 0.948 rs7259434 chr19:19428805 A/T cg03709012 chr19:19516395 GATAD2A 0.81 6.55 0.51 1.4e-9 Nonalcoholic fatty liver disease; TGCT cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg02187348 chr16:89574699 SPG7 0.6 6.51 0.5 1.69e-9 Multiple myeloma (IgH translocation); TGCT cis rs981844 0.857 rs56198877 chr4:154718970 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.9 0.62 5.71e-15 Response to statins (LDL cholesterol change); TGCT cis rs6988636 1.000 rs4282551 chr8:124185916 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg10295955 chr4:187884368 NA -0.97 -14.67 -0.8 7e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs3892630 0.878 rs1559177 chr19:33210646 A/G cg22980127 chr19:33182716 NUDT19 0.71 5.15 0.42 9.79e-7 Red blood cell traits; TGCT cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg03303774 chr4:1407052 NA -0.31 -4.93 -0.4 2.6e-6 Obesity-related traits; TGCT cis rs5769765 0.865 rs9616369 chr22:50304591 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -10.96 -0.7 5.67e-20 Schizophrenia; TGCT cis rs10461617 0.541 rs860581 chr5:56150537 A/G cg12311346 chr5:56204834 C5orf35 -0.57 -4.53 -0.38 1.38e-5 Type 2 diabetes; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg16325326 chr1:53192061 ZYG11B -0.7 -8.72 -0.62 1.53e-14 Monocyte count; TGCT cis rs8037137 0.822 rs2890156 chr15:91513157 T/A cg22570213 chr15:91497863 RCCD1 0.51 4.76 0.39 5.32e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs1008375 0.544 rs7685265 chr4:17568510 C/T cg16339924 chr4:17578868 LAP3 0.74 5.95 0.47 2.61e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2404618 0.561 rs9918765 chr8:1484467 C/T cg13402656 chr8:1511478 DLGAP2 -0.37 -6.17 -0.48 8.74e-9 Lung cancer; TGCT cis rs7918232 0.891 rs10443987 chr10:27375377 A/T cg14442939 chr10:27389572 ANKRD26 0.73 5.37 0.43 3.69e-7 Breast cancer; TGCT cis rs6121246 0.559 rs6119728 chr20:30413121 G/A cg13852791 chr20:30311386 BCL2L1 0.81 7.58 0.56 7.06e-12 Mean corpuscular hemoglobin; TGCT cis rs2637266 0.765 rs2438993 chr10:78414604 A/C cg18941641 chr10:78392320 NA 0.4 4.99 0.41 1.95e-6 Pulmonary function; TGCT cis rs8177253 0.509 rs6762415 chr3:133478557 T/G cg16414030 chr3:133502952 NA -0.57 -7.19 -0.54 5.32e-11 Iron status biomarkers; TGCT cis rs1451375 0.755 rs6969081 chr7:50624505 A/T cg18232548 chr7:50535776 DDC 0.44 7.22 0.54 4.6e-11 Malaria; TGCT trans rs1496653 0.602 rs34474714 chr3:23536891 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2404602 0.669 rs17367297 chr15:77158026 A/C cg26408565 chr15:76604113 ETFA -0.36 -4.52 -0.38 1.41e-5 Blood metabolite levels; TGCT cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg07507251 chr3:52567010 NT5DC2 0.48 6.67 0.51 7.55e-10 Bipolar disorder; TGCT cis rs425277 0.585 rs3107143 chr1:2045372 G/C cg03732007 chr1:2071316 PRKCZ -0.24 -5.38 -0.44 3.57e-7 Height; TGCT cis rs4642101 0.824 rs3889514 chr3:12844072 T/C cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs2033711 0.755 rs4801587 chr19:58936679 C/A cg12042659 chr19:58951599 ZNF132 0.52 4.81 0.4 4.24e-6 Uric acid clearance; TGCT cis rs6722750 0.506 rs12612392 chr2:64373635 G/A cg22352474 chr2:64371530 PELI1 0.76 7.09 0.54 9.13e-11 Neuroticism; TGCT cis rs992157 0.798 rs2382817 chr2:219151218 A/C cg00012203 chr2:219082015 ARPC2 0.8 7.98 0.58 8.26e-13 Colorectal cancer; TGCT cis rs7192750 0.586 rs12447045 chr16:71914617 C/G cg06353428 chr16:71660113 MARVELD3 0.8 6.93 0.53 2.04e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg02782426 chr3:40428986 ENTPD3 0.43 4.88 0.4 3.18e-6 Renal cell carcinoma; TGCT cis rs1865760 0.963 rs3846838 chr6:25911775 T/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs826838 0.967 rs6580726 chr12:39108623 T/C cg13010199 chr12:38710504 ALG10B -0.6 -4.9 -0.4 2.95e-6 Heart rate; TGCT cis rs593982 0.858 rs537385 chr11:65504900 G/A cg08755490 chr11:65554678 OVOL1 1.42 12.09 0.74 1.03e-22 Atopic dermatitis; TGCT cis rs2760061 0.626 rs592736 chr1:228116831 A/G cg18477163 chr1:228402036 OBSCN -0.32 -6.32 -0.49 4.19e-9 Diastolic blood pressure; TGCT cis rs13256369 0.708 rs11783670 chr8:8559394 G/A cg17143192 chr8:8559678 CLDN23 0.53 4.82 0.4 4.03e-6 Obesity-related traits; TGCT cis rs10170846 0.731 rs10180632 chr2:223526384 G/A cg25565276 chr2:223520875 FARSB 0.55 4.58 0.38 1.11e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs2070488 0.775 rs1073505 chr3:38566722 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.89 -0.53 2.46e-10 Electrocardiographic conduction measures; TGCT cis rs6952808 0.792 rs12537914 chr7:1948359 C/T cg04267008 chr7:1944627 MAD1L1 -0.4 -5.44 -0.44 2.71e-7 Bipolar disorder and schizophrenia; TGCT cis rs9787249 0.957 rs11206754 chr1:40216234 A/G cg19912559 chr1:40204330 PPIE 0.49 5.71 0.46 7.84e-8 Blood protein levels; TGCT cis rs10461617 0.541 rs860581 chr5:56150537 A/G cg18230493 chr5:56204884 C5orf35 -0.7 -5.03 -0.41 1.7e-6 Type 2 diabetes; TGCT cis rs10992471 0.603 rs13301537 chr9:95229047 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.74 -0.46 6.79e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7582180 0.764 rs4851293 chr2:100925106 A/T cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs10823500 0.523 rs12774848 chr10:71932436 T/C cg02100629 chr10:71892760 AIFM2 -0.47 -4.57 -0.38 1.18e-5 Blood protein levels; TGCT cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg06238570 chr21:40685208 BRWD1 -0.62 -6.3 -0.49 4.82e-9 Menarche (age at onset); TGCT cis rs5769765 1.000 rs2092982 chr22:50282204 C/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.07 -0.48 1.46e-8 Schizophrenia; TGCT cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg10802521 chr3:52805072 NEK4 -0.78 -9.99 -0.67 1.3e-17 Bipolar disorder; TGCT cis rs2840044 1.000 rs11653310 chr17:33893378 C/G cg05299278 chr17:33885742 SLFN14 0.23 5.1 0.42 1.22e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs4631830 0.869 rs7896437 chr10:51529593 A/C cg10326726 chr10:51549505 MSMB -0.24 -4.87 -0.4 3.35e-6 Prostate-specific antigen levels; TGCT cis rs35306767 0.855 rs12774985 chr10:904245 C/T cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs1865760 0.964 rs3799373 chr6:25929173 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.21 0.49 7.27e-9 Height; TGCT cis rs9549367 0.789 rs9549705 chr13:113888425 T/C cg18105134 chr13:113819100 PROZ -0.34 -5.49 -0.44 2.18e-7 Platelet distribution width; TGCT cis rs6964587 1.000 rs10234290 chr7:91716951 T/C cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg23758822 chr17:41437982 NA 0.71 6.77 0.52 4.56e-10 Menopause (age at onset); TGCT cis rs76878669 0.917 rs10219183 chr11:66090032 A/C cg18002602 chr11:66138449 SLC29A2 0.48 5.52 0.44 1.94e-7 Educational attainment (years of education); TGCT cis rs17376456 0.569 rs7735009 chr5:93260865 T/C cg21475434 chr5:93447410 FAM172A -0.62 -5.97 -0.47 2.3e-8 Diabetic retinopathy; TGCT cis rs7100689 0.599 rs6585968 chr10:82139807 T/C cg01528321 chr10:82214614 TSPAN14 0.81 8.27 0.6 1.71e-13 Post bronchodilator FEV1; TGCT cis rs9322193 0.923 rs9480031 chr6:150080011 A/C cg13206674 chr6:150067644 NUP43 0.53 4.65 0.39 8.3e-6 Lung cancer; TGCT cis rs3749237 0.576 rs62259939 chr3:49386047 G/A cg02487422 chr3:49467188 NICN1 0.66 6.89 0.53 2.45e-10 Resting heart rate; TGCT cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.07 0.41 1.4e-6 Height; TGCT trans rs17277593 0.517 rs35592667 chr9:13875829 T/C cg24852548 chr4:57522632 HOPX 0.73 6.94 0.53 1.9e-10 Endometriosis; TGCT cis rs12210905 0.841 rs28410967 chr6:27265235 T/C cg08851530 chr6:28072375 NA 1.29 5.45 0.44 2.65e-7 Hip circumference adjusted for BMI; TGCT cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg13409248 chr3:40428643 ENTPD3 0.54 4.52 0.38 1.41e-5 Renal cell carcinoma; TGCT cis rs11822910 0.737 rs2584858 chr11:57207077 C/T cg00522883 chr11:57194120 SLC43A3 0.32 4.78 0.39 4.86e-6 Platelet distribution width; TGCT cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg11890956 chr21:40555474 PSMG1 0.79 7.78 0.57 2.47e-12 Cognitive function; TGCT cis rs7949030 0.626 rs71490390 chr11:62329185 A/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.42 0.65 3.17e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg03303774 chr4:1407052 NA 0.29 4.54 0.38 1.33e-5 Obesity-related traits; TGCT cis rs11690935 0.959 rs10167419 chr2:172649826 A/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs4253772 0.591 rs10854854 chr22:46684706 C/G cg24881330 chr22:46731750 TRMU 0.99 5.45 0.44 2.64e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.76 -7.54 -0.56 8.59e-12 Prudent dietary pattern; TGCT cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg12310025 chr6:25882481 NA 0.9 9.22 0.64 9.6e-16 Blood metabolite levels; TGCT trans rs7819412 0.745 rs28464654 chr8:11080665 T/A cg15556689 chr8:8085844 FLJ10661 -0.87 -8.34 -0.6 1.2e-13 Triglycerides; TGCT cis rs425277 1.000 rs262667 chr1:2082722 T/C cg03732007 chr1:2071316 PRKCZ 0.26 5.52 0.44 1.89e-7 Height; TGCT cis rs7937682 0.587 rs571594 chr11:111359334 A/G cg09085632 chr11:111637200 PPP2R1B 0.65 6.03 0.48 1.74e-8 Primary sclerosing cholangitis; TGCT cis rs13108904 0.775 rs2279282 chr4:1216033 G/C cg05665937 chr4:1216051 CTBP1 0.26 5.16 0.42 9.54e-7 Obesity-related traits; TGCT cis rs17387100 0.901 rs55808189 chr4:15983246 T/C cg13480465 chr4:16795757 LDB2 -0.44 -5.08 -0.42 1.35e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs875971 0.895 rs1833495 chr7:65921595 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs864745 0.967 rs1635852 chr7:28189411 T/C cg23620719 chr7:28220237 JAZF1 -0.53 -4.79 -0.4 4.63e-6 Crohn's disease;Type 2 diabetes; TGCT cis rs892961 0.932 rs3987887 chr17:75414862 T/C cg05865280 chr17:75406074 SEPT9 0.3 6.97 0.53 1.65e-10 Airflow obstruction; TGCT cis rs10504229 0.683 rs16921823 chr8:58108612 G/C cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs35000415 0.515 rs13240595 chr7:128731777 C/A cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.7 -0.39 6.77e-6 Systemic lupus erythematosus; TGCT cis rs9818758 0.545 rs55921200 chr3:49189316 T/C cg00383909 chr3:49044727 WDR6 1.56 6.29 0.49 5.06e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT trans rs731174 0.559 rs10908376 chr1:38196026 G/A cg19725343 chr19:51830960 IGLON5 -0.62 -7.0 -0.53 1.44e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs624899 1.000 rs624899 chr19:11612498 C/T cg21515159 chr19:11639617 ECSIT 0.84 4.64 0.38 8.77e-6 Presence of antiphospholipid antibodies; TGCT cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg00814883 chr7:100076585 TSC22D4 -0.89 -9.26 -0.64 7.79e-16 Platelet count; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs6087771 0.851 rs6087775 chr20:30325765 G/A cg10886678 chr20:30946050 ASXL1 -0.52 -4.44 -0.37 1.97e-5 Subcortical brain region volumes;Putamen volume; TGCT cis rs13256369 0.851 rs13254997 chr8:8563753 G/C cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs7617773 0.780 rs71323395 chr3:48374077 G/A cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs1406084 0.636 rs12693842 chr2:154724833 G/C cg25703346 chr2:154729189 GALNT13 0.8 4.72 0.39 6.29e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9913156 0.802 rs4538065 chr17:4566015 G/A cg00122941 chr17:4613640 ARRB2 -0.89 -7.56 -0.56 7.65e-12 Lymphocyte counts; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg15242686 chr22:24348715 GSTTP1 0.48 6.94 0.53 1.97e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12220238 0.722 rs10762635 chr10:76403131 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.59 4.54 0.38 1.29e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1552244 0.554 rs17050705 chr3:10046398 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg14159672 chr1:205819179 PM20D1 0.71 10.1 0.67 7.19e-18 Menarche (age at onset); TGCT cis rs76419734 0.558 rs4235415 chr4:106593850 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.65 4.6 0.38 1.03e-5 Post bronchodilator FEV1; TGCT cis rs4689388 0.581 rs1801212 chr4:6302519 C/T cg14416269 chr4:6271139 WFS1 0.47 5.74 0.46 7.01e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9393692 0.905 rs6916289 chr6:26289122 A/T cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.01e-7 Educational attainment; TGCT cis rs7666738 0.830 rs4699603 chr4:99056172 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2066819 0.818 rs773652 chr12:56674766 G/A cg26714650 chr12:56694279 CS 1.57 8.21 0.59 2.5e-13 Psoriasis vulgaris; TGCT cis rs7666738 0.830 rs6819177 chr4:99040907 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs11626933 0.959 rs8005973 chr14:90774951 C/T cg14092571 chr14:90743983 NA -0.29 -6.06 -0.48 1.51e-8 Gut microbiota (bacterial taxa); TGCT cis rs921968 0.643 rs611203 chr2:219472325 G/A cg02176678 chr2:219576539 TTLL4 0.45 6.48 0.5 1.93e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs3087591 0.960 rs2905883 chr17:29550141 G/A cg24425628 chr17:29625626 OMG;NF1 0.46 7.15 0.54 6.46e-11 Hip circumference; TGCT cis rs11623869 0.553 rs11627567 chr14:103851775 C/T cg12935359 chr14:103987150 CKB -0.47 -6.09 -0.48 1.34e-8 Bone mineral density; TGCT cis rs8180040 0.620 rs6768722 chr3:47079112 G/A cg27129171 chr3:47204927 SETD2 0.71 8.51 0.61 4.8e-14 Colorectal cancer; TGCT cis rs2806561 0.606 rs10917335 chr1:23294136 A/G cg12483005 chr1:23474871 LUZP1 0.38 4.96 0.41 2.31e-6 Height; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg11905131 chr22:24372483 LOC391322 0.95 11.1 0.71 2.66e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs921968 0.643 rs539451 chr2:219426972 T/C cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs13217239 0.646 rs12523820 chr6:27001502 A/G cg05738196 chr6:26577821 NA 0.49 4.75 0.39 5.45e-6 Schizophrenia; TGCT cis rs11585357 0.947 rs11584287 chr1:17607501 G/C cg08277548 chr1:17600880 PADI3 -0.97 -9.95 -0.67 1.7e-17 Hair shape; TGCT cis rs514406 0.505 rs269287 chr1:53168842 T/C cg24675658 chr1:53192096 ZYG11B -0.74 -8.31 -0.6 1.4e-13 Monocyte count; TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs6460942 0.908 rs74801929 chr7:12232715 C/G cg06484146 chr7:12443880 VWDE -0.52 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs7568458 0.875 rs2044474 chr2:85758790 G/A cg02493740 chr2:85810744 VAMP5 -0.27 -4.83 -0.4 4e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs362272 0.524 rs2749781 chr4:3346617 T/C cg06533319 chr4:3265114 C4orf44 -0.26 -5.15 -0.42 1.01e-6 Serum sulfate level; TGCT cis rs523522 0.962 rs12371550 chr12:120987643 C/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg13012494 chr21:47604986 C21orf56 -0.37 -4.55 -0.38 1.26e-5 Testicular germ cell tumor; TGCT cis rs8077889 0.917 rs9894873 chr17:41911832 A/G cg26893861 chr17:41843967 DUSP3 1.11 13.43 0.77 6.22e-26 Triglycerides; TGCT cis rs6089829 0.925 rs11086152 chr20:61664656 T/C cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7267979 0.816 rs3746337 chr20:25208272 C/T cg03522245 chr20:25566470 NINL 0.55 5.48 0.44 2.31e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs79387448 0.745 rs72993754 chr2:103151136 A/G cg09003973 chr2:102972529 NA 0.92 6.03 0.48 1.73e-8 Gut microbiota (bacterial taxa); TGCT cis rs12220238 1.000 rs10824099 chr10:75943625 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7226408 0.590 rs72894348 chr18:34730549 C/A cg06757138 chr18:34340585 FHOD3 0.26 4.68 0.39 7.43e-6 Obesity-related traits; TGCT cis rs1150668 0.796 rs728122 chr6:28399124 G/A cg13525197 chr6:28411240 ZSCAN23 -0.53 -5.14 -0.42 1.06e-6 Pubertal anthropometrics; TGCT cis rs10892173 0.566 rs10892174 chr11:117672565 A/C cg04064380 chr11:117688259 NA -0.5 -4.48 -0.37 1.66e-5 Myopia; TGCT cis rs4273100 0.512 rs2233072 chr17:19281828 T/G cg01534423 chr17:18965556 NA -0.75 -7.86 -0.58 1.6e-12 Schizophrenia; TGCT cis rs2242116 0.932 rs7646906 chr3:46949379 G/A cg02527881 chr3:46936655 PTH1R -0.31 -5.79 -0.46 5.41e-8 Birth weight; TGCT cis rs7666738 0.830 rs28729647 chr4:99059552 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9910055 0.530 rs2269906 chr17:42294337 G/T cg13607699 chr17:42295918 UBTF -0.9 -10.34 -0.68 1.93e-18 Total body bone mineral density; TGCT cis rs7772486 0.806 rs2247317 chr6:146217570 C/T cg05347473 chr6:146136440 FBXO30 0.53 5.23 0.43 6.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.505 rs437954 chr1:53173321 C/G cg22166914 chr1:53195759 ZYG11B 0.45 7.82 0.57 2.01e-12 Monocyte count; TGCT cis rs72945132 0.882 rs947781 chr11:70212755 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9611519 0.857 rs4820434 chr22:41637119 G/T cg13695892 chr22:41940480 POLR3H -0.63 -5.96 -0.47 2.42e-8 Neuroticism; TGCT cis rs12142240 0.698 rs1475389 chr1:46816429 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs3008870 0.917 rs12044492 chr1:67461667 T/C cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs12477438 0.798 rs6705821 chr2:99602832 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg18765753 chr7:1198926 ZFAND2A -0.52 -6.08 -0.48 1.39e-8 Longevity;Endometriosis; TGCT cis rs1008375 0.933 rs4698637 chr4:17632843 A/T cg16339924 chr4:17578868 LAP3 0.64 5.19 0.42 8.36e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs854765 0.624 rs8078756 chr17:17744725 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.71 -6.69 -0.51 6.87e-10 Total body bone mineral density; TGCT cis rs72781680 0.898 rs72782126 chr2:24039901 A/C cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs9915657 0.660 rs1558748 chr17:70066502 T/C cg06234051 chr17:70120541 SOX9 -0.25 -5.44 -0.44 2.71e-7 Thyroid hormone levels; TGCT cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg13395646 chr4:1353034 KIAA1530 0.4 4.95 0.41 2.34e-6 Obesity-related traits; TGCT cis rs2180341 0.855 rs4308584 chr6:127714874 A/G cg27446573 chr6:127587934 RNF146 0.92 8.5 0.61 5.15e-14 Breast cancer; TGCT cis rs2204008 0.837 rs11514225 chr12:38076270 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.72 0.57 3.39e-12 Bladder cancer; TGCT cis rs860295 0.500 rs34995046 chr1:155988485 G/T cg05700447 chr1:155978627 NA -0.19 -4.67 -0.39 7.55e-6 Body mass index; TGCT cis rs6964587 1.000 rs2301559 chr7:91746727 T/C cg17063962 chr7:91808500 NA 0.88 9.42 0.65 3.2e-16 Breast cancer; TGCT cis rs11098499 0.691 rs2136911 chr4:120265859 G/A cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.08e-7 Corneal astigmatism; TGCT cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs11650494 0.516 rs9907942 chr17:47513891 C/T cg08112188 chr17:47440006 ZNF652 0.89 4.47 0.37 1.73e-5 Prostate cancer; TGCT cis rs9926296 0.568 rs886950 chr16:89836872 T/C cg04287289 chr16:89883240 FANCA 0.93 11.83 0.73 4.42e-22 Vitiligo; TGCT cis rs1215050 0.791 rs165252 chr4:98758728 A/C cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT trans rs2727020 0.615 rs10128582 chr11:49447424 C/T cg15704280 chr7:45808275 SEPT13 -0.77 -8.75 -0.62 1.29e-14 Coronary artery disease; TGCT cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836950 0.501 rs4818019 chr21:40694456 T/A cg11890956 chr21:40555474 PSMG1 -0.65 -6.12 -0.48 1.15e-8 Menarche (age at onset); TGCT cis rs6912958 0.630 rs9450726 chr6:88236728 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.79 -0.39 4.75e-6 Monocyte percentage of white cells; TGCT cis rs911555 0.511 rs8007489 chr14:104054572 A/G cg26031613 chr14:104095156 KLC1 -0.54 -4.99 -0.41 2.01e-6 Intelligence (multi-trait analysis); TGCT cis rs17221829 0.965 rs11018745 chr11:89443808 A/C cg02982614 chr11:89391479 FOLH1B -0.29 -5.08 -0.41 1.36e-6 Anxiety in major depressive disorder; TGCT cis rs916888 0.647 rs199523 chr17:44848517 C/A cg17911788 chr17:44343683 NA 0.51 5.9 0.47 3.3e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7824557 0.679 rs10110008 chr8:11133736 G/T cg21775007 chr8:11205619 TDH -0.57 -5.37 -0.43 3.66e-7 Retinal vascular caliber; TGCT cis rs10484885 0.824 rs72919981 chr6:90528977 T/C cg13799429 chr6:90582589 CASP8AP2 -0.46 -4.49 -0.37 1.63e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4523957 0.651 rs7214741 chr17:2085598 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.51 -0.38 1.47e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2153535 0.584 rs9502721 chr6:8541379 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.61 0.45 1.23e-7 Motion sickness; TGCT cis rs2455799 0.613 rs4685264 chr3:15858347 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.19e-6 Mean platelet volume; TGCT cis rs875971 1.000 rs6946143 chr7:65579722 A/C cg18876405 chr7:65276391 NA 0.29 4.65 0.39 8.32e-6 Aortic root size; TGCT cis rs7552404 0.727 rs2172508 chr1:76320215 A/G cg03433033 chr1:76189801 ACADM 0.59 5.9 0.47 3.21e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs853679 0.517 rs4713143 chr6:28106759 A/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs17376456 0.569 rs7729807 chr5:93104089 C/T cg25358565 chr5:93447407 FAM172A 0.76 6.61 0.51 1e-9 Diabetic retinopathy; TGCT cis rs6951245 0.554 rs79367977 chr7:1152657 G/A cg18402987 chr7:1209562 NA 0.47 4.69 0.39 7.03e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4563143 0.663 rs10417671 chr19:29235335 T/C cg12667521 chr19:29218732 NA 0.5 5.84 0.46 4.26e-8 Methadone dose in opioid dependence; TGCT cis rs76878669 0.561 rs7110944 chr11:66118217 C/T cg18002602 chr11:66138449 SLC29A2 -0.54 -6.62 -0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs12681288 0.676 rs1562921 chr8:1021986 G/T cg04851639 chr8:1020857 NA -0.36 -6.82 -0.52 3.56e-10 Schizophrenia; TGCT cis rs9467773 0.967 rs6941022 chr6:26553531 T/C cg05738196 chr6:26577821 NA 0.91 13.14 0.76 2.99e-25 Intelligence (multi-trait analysis); TGCT cis rs600550 0.963 rs4939328 chr11:60021506 C/A cg18570331 chr11:60101691 MS4A6E 0.52 4.48 0.37 1.67e-5 Lipoprotein-associated phospholipase A2 activity and mass; TGCT trans rs7615952 0.932 rs1976458 chr3:125647512 T/G cg07211511 chr3:129823064 LOC729375 -0.47 -7.55 -0.56 8.34e-12 Blood pressure (smoking interaction); TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg26338869 chr17:61819248 STRADA -0.54 -4.92 -0.4 2.64e-6 Prudent dietary pattern; TGCT cis rs981844 1.000 rs2606341 chr4:154658702 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs4713118 0.513 rs202908 chr6:28011551 C/G cg10876282 chr6:28092338 ZSCAN16 0.51 4.56 0.38 1.19e-5 Parkinson's disease; TGCT cis rs4887140 0.867 rs9806165 chr15:74063723 A/G cg05195566 chr15:74465209 ISLR -0.44 -4.5 -0.37 1.53e-5 Glucose homeostasis traits; TGCT cis rs2742417 1.000 rs2673025 chr3:45760483 A/G cg04837898 chr3:45731254 SACM1L -0.52 -5.28 -0.43 5.58e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1670533 0.932 rs610218 chr4:1080083 C/G cg27284194 chr4:1044797 NA 0.68 5.84 0.46 4.28e-8 Recombination rate (females); TGCT trans rs8073060 0.586 rs35542792 chr17:33903886 A/G cg19694781 chr19:47549865 TMEM160 0.6 13.28 0.77 1.39e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1005277 0.579 rs2505237 chr10:38438898 T/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.23 -0.59 2.17e-13 Extrinsic epigenetic age acceleration; TGCT cis rs611744 0.934 rs624311 chr8:109204437 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs2180341 0.842 rs9372860 chr6:127546605 G/A cg24812749 chr6:127587940 RNF146 0.93 6.53 0.51 1.55e-9 Breast cancer; TGCT cis rs1005277 0.540 rs4934907 chr10:38015230 A/C cg25427524 chr10:38739819 LOC399744 -0.33 -6.6 -0.51 1.07e-9 Extrinsic epigenetic age acceleration; TGCT cis rs514406 0.861 rs1571979 chr1:53237526 G/A cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs854765 0.583 rs9635697 chr17:17870394 T/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs35883536 0.626 rs7545966 chr1:101047633 G/A cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs34065801 0.584 rs1171085 chr13:36512489 A/G cg03563146 chr13:37393157 RFXAP -0.48 -4.49 -0.37 1.6e-5 Breast size; TGCT cis rs2456568 0.802 rs1574515 chr11:93629643 T/C cg26875233 chr11:93583750 C11orf90 -0.48 -6.5 -0.5 1.76e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7267979 0.903 rs2474766 chr20:25246153 A/G cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2758596 1.000 rs2758617 chr1:156160693 A/G cg25208724 chr1:156163844 SLC25A44 0.84 5.09 0.42 1.27e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs57994353 0.659 rs76259794 chr9:139377405 C/A cg13741927 chr9:139327495 INPP5E -0.23 -5.16 -0.42 9.54e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs710216 0.536 rs710221 chr1:43414200 G/A cg03128534 chr1:43423976 SLC2A1 0.7 7.41 0.55 1.74e-11 Red cell distribution width; TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg08859206 chr1:53392774 SCP2 -0.42 -6.8 -0.52 3.92e-10 Monocyte count; TGCT cis rs4665809 0.549 rs17527979 chr2:26428132 A/G cg04944784 chr2:26401820 FAM59B -0.75 -5.29 -0.43 5.46e-7 Gut microbiome composition (summer); TGCT cis rs7959452 0.649 rs4761239 chr12:69776886 T/A cg14784868 chr12:69753453 YEATS4 0.84 8.84 0.62 7.88e-15 Blood protein levels; TGCT cis rs308403 0.640 rs13110096 chr4:123633932 T/G cg10495464 chr4:123653540 BBS12;LOC729338 0.67 5.75 0.46 6.58e-8 Blood protein levels; TGCT cis rs8177253 1.000 rs8177252 chr3:133480174 C/A cg01448562 chr3:133502909 NA -0.33 -6.71 -0.52 6.3e-10 Iron status biomarkers; TGCT cis rs35146811 0.625 rs858514 chr7:99825748 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs17221829 0.673 rs10741307 chr11:89367271 G/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs617219 0.671 rs2591388 chr5:78557241 A/G cg23514016 chr5:78407564 BHMT 0.32 4.66 0.39 7.88e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs12497850 0.966 rs6792510 chr3:48723302 G/C cg16497277 chr3:49208875 KLHDC8B -0.5 -4.69 -0.39 6.97e-6 Parkinson's disease; TGCT cis rs9325144 0.560 rs1843910 chr12:38677408 T/C cg13010199 chr12:38710504 ALG10B -0.53 -4.63 -0.38 9.02e-6 Morning vs. evening chronotype; TGCT cis rs9952991 0.941 rs2847280 chr18:12779342 A/G cg23544223 chr18:12777786 NA 0.64 6.12 0.48 1.15e-8 Inflammatory skin disease; TGCT trans rs2727020 0.595 rs11040416 chr11:49566429 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.12 -0.54 7.81e-11 Coronary artery disease; TGCT cis rs12477438 0.834 rs6757019 chr2:99676936 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs7582180 0.585 rs12999151 chr2:100939333 G/A cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg03264133 chr6:25882463 NA 0.69 7.63 0.57 5.51e-12 Blood metabolite levels; TGCT cis rs2120019 1.000 rs12898259 chr15:75369780 G/A cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs7666738 0.830 rs6834014 chr4:98951431 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7017914 0.967 rs13257800 chr8:71714133 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.51 -4.72 -0.39 6.18e-6 Bone mineral density; TGCT cis rs10193935 1.000 rs10180528 chr2:42436723 T/A cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.686 rs9373473 chr6:146082282 A/G cg05347473 chr6:146136440 FBXO30 0.5 4.83 0.4 3.97e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs675209 0.680 rs12530084 chr6:7214676 C/T cg27097018 chr6:6320614 F13A1 0.36 4.92 0.4 2.67e-6 Urate levels; TGCT cis rs12510870 0.599 rs12507775 chr4:74451073 C/T cg05868023 chr4:75230803 EREG 0.53 4.7 0.39 6.81e-6 Iris color (b* coordinate); TGCT cis rs1941023 0.568 rs1373064 chr11:60168200 C/T cg08716584 chr11:60157161 MS4A7 -0.31 -4.69 -0.39 7.18e-6 Congenital heart disease (maternal effect); TGCT cis rs7914558 0.966 rs10450373 chr10:104728616 T/C cg15744005 chr10:104629667 AS3MT -0.4 -4.99 -0.41 1.97e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7914558 0.966 rs56946876 chr10:104653545 T/C cg04362960 chr10:104952993 NT5C2 0.58 5.16 0.42 9.65e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2762353 0.574 rs9467570 chr6:25699283 C/A cg12310025 chr6:25882481 NA 0.94 9.38 0.64 4.07e-16 Blood metabolite levels; TGCT cis rs10504229 1.000 rs59843034 chr8:58195756 T/G cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs9916302 0.861 rs8081033 chr17:37506650 A/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs2404602 0.716 rs117129193 chr15:76656803 A/G cg26408565 chr15:76604113 ETFA -0.4 -5.08 -0.41 1.37e-6 Blood metabolite levels; TGCT cis rs2932538 0.744 rs6537742 chr1:113085197 G/T cg10983938 chr1:113465962 AFARP1;SLC16A1 0.24 4.61 0.38 9.89e-6 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9916302 0.768 rs11078900 chr17:37614641 C/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs9611565 0.592 rs5758406 chr22:42076641 A/G cg13695892 chr22:41940480 POLR3H 0.9 9.02 0.63 2.89e-15 Vitiligo; TGCT cis rs12510870 0.729 rs10213305 chr4:74360642 C/A cg05868023 chr4:75230803 EREG 0.53 4.55 0.38 1.25e-5 Iris color (b* coordinate); TGCT cis rs4319547 0.626 rs12423420 chr12:122938466 G/A cg05707623 chr12:122985044 ZCCHC8 -0.67 -5.41 -0.44 3.08e-7 Body mass index; TGCT trans rs8073060 0.561 rs225260 chr17:33958422 T/C cg19694781 chr19:47549865 TMEM160 -0.61 -13.51 -0.77 3.85e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT trans rs6089829 0.925 rs13041507 chr20:61666180 T/C cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs597539 0.652 rs507520 chr11:68666054 C/T cg21862992 chr11:68658383 NA 0.47 6.6 0.51 1.09e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6988636 0.710 rs73339621 chr8:124138936 C/T cg22384356 chr8:124195192 FAM83A -0.42 -4.59 -0.38 1.06e-5 Urinary uromodulin levels; TGCT cis rs2180341 0.722 rs9388555 chr6:127576363 G/A cg24812749 chr6:127587940 RNF146 0.83 6.69 0.51 6.91e-10 Breast cancer; TGCT cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs9906944 0.707 rs11655950 chr17:47129121 C/T cg20966754 chr17:47091339 IGF2BP1 -0.49 -5.67 -0.45 9.38e-8 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs981844 0.712 rs897611 chr4:154755519 T/C cg14289246 chr4:154710475 SFRP2 -0.96 -8.97 -0.63 3.91e-15 Response to statins (LDL cholesterol change); TGCT cis rs3087591 0.922 rs2905805 chr17:29502856 C/A cg24425628 chr17:29625626 OMG;NF1 0.45 6.95 0.53 1.84e-10 Hip circumference; TGCT cis rs1878931 0.858 rs3760083 chr16:3450052 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.97 -10.31 -0.68 2.26e-18 Body mass index (adult); TGCT cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg11062466 chr8:58055876 NA 0.46 4.81 0.4 4.29e-6 Developmental language disorder (linguistic errors); TGCT cis rs12042938 0.507 rs2570408 chr1:231732934 C/T cg04892437 chr1:231737901 TSNAX-DISC1 -0.38 -4.45 -0.37 1.85e-5 Neuranatomic and neurocognitive phenotypes; TGCT cis rs7439150 1.000 rs72681213 chr4:155479689 G/A cg22130008 chr4:155548532 NA -0.44 -5.59 -0.45 1.36e-7 Fibrinogen levels; TGCT cis rs875971 0.862 rs2420611 chr7:65999320 A/G cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs9868809 1.000 rs9868809 chr3:48681053 C/T cg00383909 chr3:49044727 WDR6 0.93 4.52 0.38 1.4e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7191700 0.836 rs10163410 chr16:11430615 G/C cg00044050 chr16:11439710 C16orf75 0.68 5.7 0.46 8.46e-8 Multiple sclerosis; TGCT cis rs11122272 0.735 rs2474631 chr1:231541341 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.24 -0.49 6.23e-9 Hemoglobin concentration; TGCT cis rs2204008 0.837 rs7315255 chr12:37949279 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs1018836 0.663 rs4735190 chr8:91509601 A/G cg16814680 chr8:91681699 NA -0.84 -8.49 -0.61 5.44e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs12477438 0.798 rs6542849 chr2:99578493 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg27588902 chr6:42928151 GNMT -0.49 -5.93 -0.47 2.85e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs769267 0.895 rs2916069 chr19:19520358 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.25 0.43 6.3e-7 Tonsillectomy; TGCT cis rs9443645 0.901 rs9361480 chr6:79724429 C/T cg05283184 chr6:79620031 NA -0.2 -4.63 -0.38 9.08e-6 Intelligence (multi-trait analysis); TGCT cis rs1497406 0.744 rs12562207 chr1:16508059 G/A cg20430773 chr1:16534157 ARHGEF19 0.56 6.28 0.49 5.24e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9859260 0.744 rs557527 chr3:195780709 G/A cg02975922 chr3:195473998 MUC4 0.25 5.09 0.42 1.3e-6 Mean corpuscular volume; TGCT cis rs1552244 0.554 rs3846167 chr3:9996426 T/C cg00149659 chr3:10157352 C3orf10 0.66 4.89 0.4 3.04e-6 Alzheimer's disease; TGCT cis rs7267979 0.932 rs928121 chr20:25534818 A/G cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs748404 0.578 rs573615 chr15:43614281 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.82 0.4 4.07e-6 Lung cancer; TGCT trans rs6089829 0.962 rs7267951 chr20:61665979 A/G cg17470723 chr8:74884337 TCEB1 0.74 6.92 0.53 2.19e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs8062405 1.000 rs11861174 chr16:28871989 A/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2180341 0.781 rs7760652 chr6:127572096 A/G cg27446573 chr6:127587934 RNF146 0.91 8.5 0.61 5.12e-14 Breast cancer; TGCT cis rs13102973 0.965 rs55967588 chr4:135860189 G/A cg14419869 chr4:135874104 NA 0.24 4.49 0.37 1.6e-5 Subjective well-being; TGCT cis rs67478160 0.643 rs8005594 chr14:104279889 T/C cg26031613 chr14:104095156 KLC1 -0.63 -6.56 -0.51 1.3e-9 Schizophrenia; TGCT cis rs67311347 1.000 rs6793596 chr3:40457795 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs367615 0.679 rs11241021 chr5:108812090 T/G cg17395555 chr5:108820864 NA 0.31 5.85 0.47 4.07e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs11239930 0.517 rs4950354 chr1:146554223 T/C cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT trans rs28735056 0.967 rs11662248 chr18:77619009 C/T cg05926928 chr17:57297772 GDPD1 -0.7 -7.61 -0.56 5.93e-12 Schizophrenia; TGCT cis rs6089829 0.855 rs6090203 chr20:61663632 G/A cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs9341808 0.754 rs3805885 chr6:80996751 C/G cg08355045 chr6:80787529 NA -0.26 -4.54 -0.38 1.34e-5 Sitting height ratio; TGCT cis rs11578119 0.836 rs12130520 chr1:170539500 G/A cg09767346 chr1:170501363 GORAB 0.58 4.61 0.38 9.77e-6 Male-pattern baldness; TGCT cis rs4589502 0.512 rs4395023 chr15:67097208 G/A cg12317470 chr15:67143691 NA 0.56 4.97 0.41 2.16e-6 Lung cancer (smoking interaction); TGCT cis rs651907 0.557 rs2318090 chr3:101474933 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.68 0.39 7.44e-6 Colorectal cancer; TGCT cis rs7017914 0.905 rs4434651 chr8:71947187 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.27 -0.43 5.81e-7 Bone mineral density; TGCT cis rs17539620 0.628 rs62432728 chr6:154829511 G/C cg20019720 chr6:154832845 CNKSR3 0.48 4.45 0.37 1.88e-5 Lipoprotein (a) levels; TGCT cis rs4824093 0.610 rs73443906 chr22:50274293 A/G cg20569369 chr22:51173646 NA 0.28 4.69 0.39 7.23e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7209700 0.862 rs2015729 chr17:45354493 G/A cg21624342 chr17:45890973 OSBPL7 0.16 4.6 0.38 1.04e-5 IgG glycosylation; TGCT cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2188554 0.785 rs213952 chr7:117203417 A/G cg09181792 chr7:117119393 CFTR 0.48 4.47 0.37 1.74e-5 Esophageal adenocarcinoma; TGCT cis rs909002 0.962 rs10798883 chr1:32140305 C/T cg11573219 chr1:32083031 HCRTR1 -0.39 -4.72 -0.39 6.21e-6 Intelligence (multi-trait analysis); TGCT cis rs875971 0.642 rs35526611 chr7:66094008 C/T cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs2180341 0.781 rs7742161 chr6:127571676 T/C cg27446573 chr6:127587934 RNF146 0.91 8.5 0.61 5.12e-14 Breast cancer; TGCT cis rs3617 0.522 rs6773650 chr3:52897095 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.59 0.38 1.08e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7172809 0.561 rs74026923 chr15:77797927 C/T cg22256960 chr15:77711686 NA -0.5 -4.8 -0.4 4.45e-6 Glucose homeostasis traits; TGCT cis rs1215050 0.704 rs783915 chr4:99023151 C/G cg17366294 chr4:99064904 C4orf37 0.56 5.9 0.47 3.25e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28595532 0.920 rs116098781 chr4:119771613 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs28595532 1.000 rs56225646 chr4:119651217 T/C cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg08280861 chr8:58055591 NA 0.37 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.95 -0.53 1.82e-10 Prostate cancer; TGCT cis rs8038465 0.622 rs17185525 chr15:73885539 T/C cg15420318 chr15:73925796 NPTN 0.64 6.8 0.52 3.9e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3096299 0.900 rs744327 chr16:89439270 C/T cg06640241 chr16:89574553 SPG7 0.69 6.7 0.52 6.6e-10 Multiple myeloma (IgH translocation); TGCT cis rs4409675 0.619 rs12070173 chr1:28231955 G/C cg23691781 chr1:28212827 C1orf38 0.25 5.38 0.43 3.59e-7 Corneal astigmatism; TGCT cis rs6987853 0.830 rs12542919 chr8:42356035 C/T cg20539142 chr8:42623718 CHRNA6 0.19 4.52 0.38 1.44e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs9303401 0.659 rs56162835 chr17:56687315 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.63e-9 Blood metabolite levels; TGCT cis rs2242116 0.727 rs4683298 chr3:46966387 C/G cg02527881 chr3:46936655 PTH1R -0.3 -5.59 -0.45 1.4e-7 Birth weight; TGCT cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg11941060 chr3:133502564 NA -0.26 -5.32 -0.43 4.74e-7 Iron status biomarkers; TGCT cis rs4509693 1.000 rs4509693 chr10:102501571 C/T cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg24250549 chr1:154909240 PMVK 0.66 6.44 0.5 2.33e-9 Prostate cancer; TGCT cis rs11080466 0.928 rs11659686 chr18:10898527 A/C cg02393756 chr18:9912783 VAPA -0.27 -4.74 -0.39 5.68e-6 Non-small cell lung cancer; TGCT cis rs7552404 0.727 rs1159214 chr1:76317910 G/T cg03433033 chr1:76189801 ACADM -0.59 -6.06 -0.48 1.51e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13217239 0.621 rs12527231 chr6:27001288 G/A cg02458000 chr6:26745757 NA 0.5 4.61 0.38 1e-5 Schizophrenia; TGCT cis rs10089 1.000 rs17764954 chr5:127514436 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 7.83 0.58 1.83e-12 Ileal carcinoids; TGCT trans rs12599106 0.792 rs12597352 chr16:34638507 A/T cg18110333 chr6:292329 DUSP22 -0.66 -7.25 -0.55 3.97e-11 Menopause (age at onset); TGCT cis rs7824557 0.591 rs2043510 chr8:11225168 G/A cg21775007 chr8:11205619 TDH -0.74 -7.38 -0.55 2.02e-11 Retinal vascular caliber; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg10150615 chr22:24372951 LOC391322 0.76 6.37 0.5 3.44e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs11722228 1.000 rs6823877 chr4:9921931 T/C cg00071950 chr4:10020882 SLC2A9 -0.49 -5.04 -0.41 1.58e-6 Gout;Urate levels;Serum uric acid levels; TGCT cis rs4319547 0.915 rs1473553 chr12:122985057 G/T cg23029597 chr12:123009494 RSRC2 -0.29 -4.87 -0.4 3.34e-6 Body mass index; TGCT cis rs7296418 0.636 rs11057261 chr12:123797567 T/C cg00376283 chr12:123451042 ABCB9 0.62 5.32 0.43 4.7e-7 Platelet count; TGCT cis rs2180341 1.000 rs6903878 chr6:127638600 C/G cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs6598955 0.671 rs7551557 chr1:26596614 G/A cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs11190604 0.943 rs9420792 chr10:102258439 C/T cg23241863 chr10:102295624 HIF1AN 0.69 5.3 0.43 5.05e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7209700 0.821 rs4634 chr17:45369789 G/A cg21624342 chr17:45890973 OSBPL7 0.19 5.09 0.42 1.32e-6 IgG glycosylation; TGCT cis rs12049351 0.722 rs4148763 chr1:229654960 A/T cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs78487399 0.808 rs75321787 chr2:43843071 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.69 4.73 0.39 6.01e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs28595532 0.702 rs72670250 chr4:119337134 T/C cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs950169 0.580 rs17532346 chr15:85171495 A/C cg17173187 chr15:85201210 NMB 0.61 6.95 0.53 1.84e-10 Schizophrenia; TGCT cis rs7572733 0.534 rs700685 chr2:198715972 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs3617 0.598 rs56214994 chr3:52878600 G/C cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs35306767 0.903 rs12250937 chr10:900209 C/T cg20503657 chr10:835505 NA 0.75 10.39 0.68 1.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs1971762 0.730 rs7963016 chr12:54072819 T/A cg22997177 chr12:54070527 ATP5G2 -0.33 -4.47 -0.37 1.76e-5 Height; TGCT cis rs28595532 0.920 rs114093638 chr4:119729819 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs1670533 0.697 rs658846 chr4:1084723 G/C cg19318889 chr4:1322082 MAEA 0.21 4.5 0.37 1.56e-5 Recombination rate (females); TGCT cis rs10465746 0.967 rs4907191 chr1:84444165 A/G cg10977910 chr1:84465055 TTLL7 -0.65 -6.57 -0.51 1.27e-9 Obesity-related traits; TGCT cis rs13082711 0.554 rs6804440 chr3:27398150 C/T cg02860705 chr3:27208620 NA 0.42 5.81 0.46 4.86e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs881375 0.967 rs1930778 chr9:123641369 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.51 5.63 0.45 1.14e-7 Rheumatoid arthritis; TGCT cis rs1903068 0.657 rs73236104 chr4:55990954 G/C cg16572876 chr4:56024045 NA 0.42 4.43 0.37 2.01e-5 Endometriosis; TGCT cis rs763121 0.962 rs6001159 chr22:38966487 A/G cg06022373 chr22:39101656 GTPBP1 0.76 7.34 0.55 2.45e-11 Menopause (age at onset); TGCT cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg10295955 chr4:187884368 NA -0.97 -14.7 -0.8 6.19e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs1865760 0.865 rs9467645 chr6:25955176 G/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs6964587 1.000 rs6956431 chr7:91750016 T/C cg17063962 chr7:91808500 NA 0.87 9.18 0.64 1.18e-15 Breast cancer; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg00080972 chr5:178986291 RUFY1 -0.59 -7.58 -0.56 6.89e-12 Lung cancer; TGCT cis rs17102423 0.661 rs11627540 chr14:65614892 C/T cg11161011 chr14:65562177 MAX -0.46 -5.83 -0.46 4.56e-8 Obesity-related traits; TGCT cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.861 rs2448792 chr1:53268313 T/C cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs767764 0.592 rs17091944 chr8:13202480 G/A cg23717764 chr8:12526205 NA 0.25 4.61 0.38 9.93e-6 Nose size; TGCT cis rs6977940 0.512 rs11765726 chr7:2850878 A/G cg19731401 chr7:2775893 GNA12 0.35 4.74 0.39 5.81e-6 White matter integrity; TGCT cis rs72781680 0.821 rs72790304 chr2:24108557 G/A cg08917208 chr2:24149416 ATAD2B 0.8 5.09 0.42 1.28e-6 Lymphocyte counts; TGCT cis rs13242816 1.000 rs62468978 chr7:116127099 A/G cg02799643 chr7:116139180 CAV2 -0.45 -5.46 -0.44 2.49e-7 P wave duration; TGCT cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9303401 0.614 rs68100606 chr17:56500898 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 6.12 0.48 1.15e-8 Cognitive test performance; TGCT cis rs2982552 0.967 rs2982558 chr6:152056146 A/G cg22157087 chr6:152012887 ESR1 0.18 4.59 0.38 1.08e-5 Bone properties (heel); TGCT cis rs56104184 0.723 rs73063515 chr19:49407715 C/T cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs28595532 0.920 rs116331303 chr4:119754542 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs12497850 0.863 rs4974084 chr3:48939080 G/A cg16497277 chr3:49208875 KLHDC8B -0.55 -5.08 -0.41 1.36e-6 Parkinson's disease; TGCT cis rs1867631 1.000 rs7546090 chr1:67083981 G/A cg13052034 chr1:66999238 SGIP1 0.58 4.88 0.4 3.26e-6 Menopause (age at onset); TGCT cis rs1005277 0.522 rs289648 chr10:37971837 T/C cg25427524 chr10:38739819 LOC399744 -0.33 -6.48 -0.5 1.99e-9 Extrinsic epigenetic age acceleration; TGCT cis rs28493229 0.708 rs111410535 chr19:41158441 C/T cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs9457247 0.529 rs6907666 chr6:167523395 A/G cg07741184 chr6:167504864 NA -0.27 -5.52 -0.44 1.92e-7 Crohn's disease; TGCT cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg16423285 chr20:60520624 NA -0.69 -7.11 -0.54 7.98e-11 Body mass index; TGCT cis rs9640161 0.830 rs3735165 chr7:150068371 T/C cg21361702 chr7:150065534 REPIN1 0.5 4.6 0.38 1.01e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg11062466 chr8:58055876 NA 0.44 4.62 0.38 9.46e-6 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.919 rs7406870 chr17:29590617 G/A cg24425628 chr17:29625626 OMG;NF1 0.42 6.14 0.48 1.04e-8 Hip circumference; TGCT cis rs12893668 0.572 rs34000399 chr14:104101417 T/C cg26031613 chr14:104095156 KLC1 -0.59 -5.08 -0.42 1.34e-6 Reticulocyte count; TGCT cis rs858239 0.536 rs6961109 chr7:23252413 C/T cg05602783 chr7:23145260 KLHL7 -0.72 -5.79 -0.46 5.36e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs1008375 0.966 rs2315553 chr4:17627332 T/C cg16339924 chr4:17578868 LAP3 0.71 5.77 0.46 6.04e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.830 rs7662948 chr4:99020132 G/C cg18180107 chr4:99064573 C4orf37 0.51 4.64 0.38 8.77e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.21 0.49 7.27e-9 Bipolar disorder; TGCT cis rs9302065 0.565 rs2992908 chr13:95960600 G/A cg26751094 chr13:95954534 ABCC4 -0.4 -6.74 -0.52 5.33e-10 Blood metabolite levels; TGCT cis rs7113874 0.569 rs10160805 chr11:8600393 C/T cg14521421 chr11:8862019 ST5 -0.28 -4.44 -0.37 1.96e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg22618164 chr12:122356400 WDR66 0.62 6.43 0.5 2.53e-9 Mean corpuscular volume; TGCT cis rs11031096 0.754 rs3817657 chr11:4142592 T/C cg18678763 chr11:4115507 RRM1 -0.46 -5.73 -0.46 7.29e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7267979 1.000 rs2257808 chr20:25266450 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2777491 0.915 rs9302109 chr15:41612180 G/T cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.44 -0.68 1.07e-18 Ulcerative colitis; TGCT cis rs4727443 0.866 rs13243708 chr7:99616291 T/C cg13334819 chr7:99746414 C7orf59 0.56 4.71 0.39 6.63e-6 Interstitial lung disease; TGCT cis rs7267979 0.844 rs2424703 chr20:25270124 G/A cg16686733 chr20:25566563 NINL 0.52 4.93 0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1146942 0.590 rs9531035 chr13:80824788 T/A cg11599984 chr13:80914014 SPRY2 0.79 4.82 0.4 4.19e-6 Diastolic blood pressure; TGCT cis rs7267979 1.000 rs4813562 chr20:25352588 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7570971 1.000 rs1375131 chr2:135954797 T/C cg07169764 chr2:136633963 MCM6 0.53 4.77 0.39 5.03e-6 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs12479064 0.703 rs28382977 chr2:100018304 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.73 -6.44 -0.5 2.42e-9 Chronic sinus infection; TGCT cis rs2535633 0.631 rs2245424 chr3:53003021 G/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.45 -0.37 1.91e-5 Body mass index; TGCT cis rs1691799 0.899 rs1168351 chr12:66752505 A/G cg16791601 chr12:66731901 HELB -0.29 -6.17 -0.48 8.77e-9 White blood cell count (basophil); TGCT cis rs10504229 0.679 rs11783965 chr8:58130510 T/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs367943 0.901 rs348951 chr5:112822017 G/C cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs7586879 0.616 rs876186 chr2:25125585 C/T cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs17253792 0.822 rs74720318 chr14:56099828 G/T cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs1008375 1.000 rs10939744 chr4:17664473 G/T cg10189774 chr4:17578691 LAP3 0.54 5.08 0.41 1.38e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs916888 0.821 rs70600 chr17:44860021 C/T cg22433210 chr17:43662623 NA 1.0 7.13 0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs4722166 0.695 rs35779989 chr7:22800314 A/C cg26061582 chr7:22766209 IL6 0.48 6.25 0.49 6.15e-9 Lung cancer; TGCT cis rs9399137 0.507 rs11759077 chr6:135381351 A/G cg24558204 chr6:135376177 HBS1L 0.47 4.73 0.39 5.98e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT trans rs7618501 0.521 rs6774354 chr3:49961780 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.83 8.58 0.61 3.34e-14 Intelligence (multi-trait analysis); TGCT cis rs4925386 0.681 rs2427296 chr20:60927475 G/A cg24112000 chr20:60950667 NA -0.37 -4.45 -0.37 1.9e-5 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs7923609 1.000 rs4400684 chr10:65012687 A/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.54 -0.38 1.32e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs6089829 0.962 rs6062393 chr20:61663230 G/A cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs17767294 0.708 rs72851158 chr6:28060485 G/C cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs11578119 0.866 rs11586686 chr1:170354846 C/T cg09767346 chr1:170501363 GORAB 0.61 4.57 0.38 1.18e-5 Male-pattern baldness; TGCT cis rs78487399 0.808 rs78481334 chr2:43796135 T/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.68 4.51 0.38 1.51e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs798554 0.704 rs798513 chr7:2782493 C/T cg25467336 chr7:2757616 NA -0.24 -4.62 -0.38 9.58e-6 Height; TGCT cis rs7089973 0.668 rs61868024 chr10:116637939 A/G cg03647239 chr10:116582469 FAM160B1 0.58 5.28 0.43 5.7e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs4273100 0.541 rs973649 chr17:19292068 A/G cg01534423 chr17:18965556 NA -0.75 -7.83 -0.58 1.83e-12 Schizophrenia; TGCT cis rs62103177 0.673 rs62096717 chr18:77616819 C/T cg12964065 chr18:77638022 KCNG2 0.31 4.46 0.37 1.84e-5 Opioid sensitivity; TGCT cis rs858239 0.539 rs4295546 chr7:23191021 C/T cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs6547741 1.000 rs4666007 chr2:27856495 T/C cg27432699 chr2:27873401 GPN1 0.18 4.63 0.38 9.05e-6 Oral cavity cancer; TGCT cis rs748404 0.587 rs9920879 chr15:43639770 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs6964587 1.000 rs7800582 chr7:91701346 G/A cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs2549003 0.870 rs10053046 chr5:131821558 A/G cg02551604 chr5:131831745 NA -0.89 -11.95 -0.73 2.33e-22 Asthma (sex interaction); TGCT cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089584 0.566 rs6061401 chr20:60607482 G/A cg13770153 chr20:60521292 NA -0.39 -4.67 -0.39 7.61e-6 Body mass index; TGCT cis rs7845219 0.544 rs10956932 chr8:95948202 C/T cg13393036 chr8:95962371 TP53INP1 0.45 5.31 0.43 4.91e-7 Type 2 diabetes; TGCT cis rs7552404 0.690 rs7549863 chr1:76327923 T/C cg03433033 chr1:76189801 ACADM -0.59 -5.97 -0.47 2.34e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6835098 0.924 rs12639929 chr4:174156538 C/T cg08422745 chr4:174089978 GALNT7 -0.9 -9.71 -0.66 6.56e-17 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs2455799 0.559 rs10514667 chr3:15915154 C/T cg12172478 chr3:16357591 RFTN1 -0.36 -5.29 -0.43 5.33e-7 Mean platelet volume; TGCT cis rs7666738 0.830 rs4699589 chr4:98973889 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1691799 0.867 rs6581677 chr12:66770379 C/G cg16791601 chr12:66731901 HELB -0.29 -6.02 -0.48 1.82e-8 White blood cell count (basophil); TGCT cis rs698813 0.637 rs4952706 chr2:44500536 T/C cg00619915 chr2:44497795 NA -0.22 -4.91 -0.4 2.79e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs1865760 0.566 rs1539183 chr6:26075051 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs597539 0.690 rs578791 chr11:68625809 C/T cg04772025 chr11:68637568 NA 0.62 6.63 0.51 9.08e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs636291 0.517 rs11121579 chr1:10541824 G/C cg17425144 chr1:10567563 PEX14 0.53 7.5 0.56 1.06e-11 Prostate cancer; TGCT cis rs8068544 0.606 rs77681389 chr17:40154419 T/C cg13092355 chr17:39992602 KLHL10;NT5C3L -0.95 -4.55 -0.38 1.24e-5 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs1552244 0.882 rs17050699 chr3:10037167 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs2073300 1.000 rs6114138 chr20:23457350 G/A cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs2718812 0.792 rs1867504 chr3:133410661 C/T cg08048268 chr3:133502702 NA -0.38 -4.63 -0.38 9.04e-6 Iron status biomarkers; TGCT cis rs11190604 1.000 rs2495741 chr10:102331795 A/G cg16342193 chr10:102329863 NA -0.43 -5.39 -0.44 3.42e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs589448 0.538 rs622656 chr12:69753595 C/T cg11871910 chr12:69753446 YEATS4 0.61 5.37 0.43 3.67e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1451375 0.785 rs10278338 chr7:50630270 C/T cg18232548 chr7:50535776 DDC 0.44 6.85 0.52 3.08e-10 Malaria; TGCT cis rs9394841 0.646 rs9471676 chr6:41815192 C/T cg08135965 chr6:41755394 TOMM6 0.54 4.94 0.41 2.46e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs854765 0.624 rs1889018 chr17:17734740 G/A cg09796270 chr17:17721594 SREBF1 -0.27 -5.19 -0.42 8.39e-7 Total body bone mineral density; TGCT cis rs10423674 0.526 rs11085241 chr19:18828546 G/A cg14292368 chr19:18793705 CRTC1 -0.53 -4.89 -0.4 3.1e-6 Menarche (age at onset); TGCT cis rs7172809 0.573 rs13380152 chr15:77436386 A/T cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs10782582 0.609 rs5745469 chr1:76347394 G/A cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs7949030 0.626 rs61296092 chr11:62320838 T/C cg22862634 chr11:62369728 EML3;MTA2 0.71 9.06 0.63 2.33e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4478858 0.684 rs11578407 chr1:31728543 A/G cg00250761 chr1:31883323 NA -0.27 -4.88 -0.4 3.13e-6 Alcohol dependence; TGCT cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg01802117 chr1:53393560 SCP2 0.46 5.52 0.44 1.85e-7 Monocyte count; TGCT cis rs2046867 0.862 rs62252360 chr3:72838551 C/T cg25664220 chr3:72788482 NA -0.52 -6.66 -0.51 7.86e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs875971 1.000 rs1540651 chr7:65650121 C/T cg11764359 chr7:65958608 NA -0.6 -5.32 -0.43 4.68e-7 Aortic root size; TGCT cis rs7917772 0.636 rs7894154 chr10:104524647 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.56 -4.59 -0.38 1.07e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs28735056 0.846 rs12958903 chr18:77628996 A/G cg05926928 chr17:57297772 GDPD1 0.65 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg18538332 chr22:24372958 LOC391322 -1.01 -12.94 -0.76 9.13e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs919433 0.617 rs13018267 chr2:198545592 G/C cg00792783 chr2:198669748 PLCL1 -0.55 -5.04 -0.41 1.62e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs12477438 0.765 rs7605218 chr2:99593080 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs909674 0.775 rs4821896 chr22:39833437 T/C cg11247378 chr22:39784982 NA -0.73 -8.6 -0.61 3e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2657888 0.965 rs2694909 chr12:56934928 T/C cg23002907 chr12:56915593 RBMS2 0.44 6.15 0.48 9.65e-9 Adiponectin levels; TGCT cis rs6752107 0.901 rs28454240 chr2:234145618 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.97 0.41 2.16e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1375194 0.509 rs62150473 chr2:33822320 G/A cg04131969 chr2:33951647 MYADML -0.56 -4.86 -0.4 3.51e-6 Response to antidepressants in depression; TGCT cis rs854765 0.647 rs9303144 chr17:17977355 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.72 7.32 0.55 2.74e-11 Total body bone mineral density; TGCT cis rs1964356 0.524 rs7839585 chr8:8854235 C/G cg06636001 chr8:8085503 FLJ10661 -0.68 -5.79 -0.46 5.53e-8 Mean corpuscular volume; TGCT cis rs2115630 0.846 rs8024538 chr15:85368419 A/T cg12863693 chr15:85201151 NMB -0.38 -4.95 -0.41 2.32e-6 P wave terminal force; TGCT cis rs2197308 0.667 rs11181073 chr12:37898543 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.82 0.57 1.94e-12 Morning vs. evening chronotype; TGCT trans rs10802346 0.545 rs10802345 chr1:246372834 C/T cg13514129 chr1:39547527 MACF1 0.84 7.49 0.56 1.12e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs9660992 0.573 rs1172161 chr1:205206495 C/T cg00857998 chr1:205179979 DSTYK 0.51 4.67 0.39 7.77e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs9372498 0.536 rs9489452 chr6:118910868 G/C cg21191810 chr6:118973309 C6orf204 -0.39 -5.13 -0.42 1.07e-6 Diastolic blood pressure; TGCT cis rs6740322 0.748 rs6755601 chr2:43483044 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.3 -0.49 4.81e-9 Coronary artery disease; TGCT cis rs76419734 0.558 rs73837046 chr4:106523319 G/A cg24545054 chr4:106630052 GSTCD;INTS12 0.81 4.53 0.38 1.35e-5 Post bronchodilator FEV1; TGCT cis rs4824093 0.610 rs73441745 chr22:50237606 G/A cg20569369 chr22:51173646 NA 0.27 4.54 0.38 1.3e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs208520 0.526 rs7775830 chr6:66755249 A/G cg07460842 chr6:66804631 NA 1.03 13.88 0.78 5.09e-27 Exhaled nitric oxide output; TGCT cis rs1005277 0.579 rs1740737 chr10:38499365 G/T cg25427524 chr10:38739819 LOC399744 -0.41 -8.56 -0.61 3.6e-14 Extrinsic epigenetic age acceleration; TGCT cis rs1018836 0.923 rs11784529 chr8:91640956 C/A cg16814680 chr8:91681699 NA -0.9 -9.65 -0.65 8.98e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs13082711 0.953 rs13096477 chr3:27490194 T/C cg02860705 chr3:27208620 NA 0.34 4.77 0.39 5.18e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs939658 0.728 rs12904789 chr15:79412589 G/A cg17916960 chr15:79447300 NA -0.46 -6.38 -0.5 3.24e-9 Refractive error; TGCT trans rs561341 0.882 rs28649357 chr17:30367190 A/G cg20587970 chr11:113659929 NA -0.96 -12.59 -0.75 6.48e-24 Hip circumference adjusted for BMI; TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg24675658 chr1:53192096 ZYG11B -0.7 -7.91 -0.58 1.22e-12 Monocyte count; TGCT cis rs2074585 0.647 rs2601172 chr15:90915666 A/G cg22089800 chr15:90895588 ZNF774 0.82 9.2 0.64 1.07e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg01802117 chr1:53393560 SCP2 -0.44 -5.52 -0.44 1.86e-7 Monocyte count; TGCT cis rs903263 0.601 rs953197 chr1:84541286 T/C cg09664975 chr1:84543551 PRKACB 0.5 4.92 0.4 2.73e-6 Breast cancer (male); TGCT cis rs2243480 0.901 rs34807232 chr7:65965133 G/A cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6545883 0.929 rs2421203 chr2:61669248 C/A cg15711740 chr2:61764176 XPO1 -0.56 -5.12 -0.42 1.12e-6 Tuberculosis; TGCT cis rs3806843 0.619 rs2569160 chr5:140028774 T/C cg19875535 chr5:140030758 IK -0.36 -6.34 -0.49 3.84e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs17401966 0.964 rs2027331 chr1:10276718 C/T cg21474053 chr1:11182049 MTOR 0.18 4.43 0.37 2.01e-5 Hepatocellular carcinoma; TGCT cis rs477895 0.838 rs1058735 chr11:64000410 C/G cg04317338 chr11:64019027 PLCB3 0.81 6.93 0.53 2.07e-10 Mean platelet volume; TGCT cis rs4819052 0.840 rs914217 chr21:46698299 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 5.47 0.44 2.34e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2228479 0.717 rs9282682 chr16:89805794 A/G cg04287289 chr16:89883240 FANCA 0.74 4.47 0.37 1.74e-5 Skin colour saturation; TGCT cis rs7089973 0.604 rs17663670 chr10:116596269 A/C cg03647239 chr10:116582469 FAM160B1 -0.59 -5.74 -0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9549260 0.755 rs4941987 chr13:41195992 T/C cg21288729 chr13:41239152 FOXO1 1.0 10.23 0.68 3.52e-18 Red blood cell count; TGCT cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs6089829 0.888 rs6011559 chr20:61675620 C/T cg02380750 chr20:61661411 NA -0.33 -5.11 -0.42 1.2e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs3008870 1.000 rs2985822 chr1:67404910 T/G cg11518657 chr1:67396239 MIER1 0.54 4.68 0.39 7.24e-6 Lymphocyte percentage of white cells; TGCT cis rs9427116 0.502 rs9427104 chr1:154589232 C/T cg17218026 chr1:154582156 ADAR 0.31 7.97 0.58 8.71e-13 Blood protein levels; TGCT cis rs4722585 0.533 rs12334205 chr7:26202490 G/A cg07876897 chr7:26191696 NFE2L3 0.4 5.57 0.45 1.53e-7 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs1008375 0.966 rs10939736 chr4:17581617 T/A cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7769051 1.000 rs9493438 chr6:133098349 T/C cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs6988636 1.000 rs17323510 chr8:124186089 A/G cg22384356 chr8:124195192 FAM83A 0.42 5.68 0.45 9.09e-8 Urinary uromodulin levels; TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg13397359 chr6:42928475 GNMT 0.73 6.54 0.51 1.43e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs11711311 0.712 rs10804510 chr3:113340700 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.68 -5.77 -0.46 5.99e-8 IgG glycosylation; TGCT cis rs6088590 0.550 rs12624640 chr20:32952125 G/A cg24642439 chr20:33292090 TP53INP2 0.6 5.1 0.42 1.23e-6 Coronary artery disease; TGCT cis rs9393692 1.000 rs2393593 chr6:26285683 T/C cg13736514 chr6:26305472 NA -0.43 -6.28 -0.49 5.32e-9 Educational attainment; TGCT cis rs11249608 0.548 rs2132672 chr5:178457742 A/C cg21905437 chr5:178450457 ZNF879 0.44 4.62 0.38 9.35e-6 Pubertal anthropometrics; TGCT cis rs7666738 0.716 rs11097615 chr4:99092773 T/C cg17366294 chr4:99064904 C4orf37 0.71 6.95 0.53 1.86e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.966 rs6083818 chr20:25346082 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs9436116 1 rs9436116 chr1:150454724 G/T cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Morning vs. evening chronotype; TGCT cis rs6693567 0.545 rs5011187 chr1:150422761 T/C cg09579323 chr1:150459698 TARS2 0.52 4.62 0.38 9.55e-6 Migraine; TGCT cis rs9393777 0.513 rs9368450 chr6:26652489 A/C cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs4911259 0.552 rs6058926 chr20:31465450 T/C cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs4975709 0.569 rs931509 chr5:1858821 A/T cg14773178 chr5:1868261 NA 0.34 5.62 0.45 1.18e-7 Cardiovascular disease risk factors; TGCT cis rs317865 0.867 rs73234637 chr4:16178866 C/T cg04764131 chr4:16228633 TAPT1;FLJ39653 0.75 4.86 0.4 3.46e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs2153535 0.580 rs1319169 chr6:8464456 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs751728 0.931 rs2296746 chr6:33744711 C/T cg13859433 chr6:33739653 LEMD2 -0.39 -7.13 -0.54 7.29e-11 Crohn's disease; TGCT cis rs2956278 0.717 rs2956294 chr12:84678552 C/T cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg14159672 chr1:205819179 PM20D1 0.63 7.92 0.58 1.16e-12 Menarche (age at onset); TGCT cis rs854765 0.583 rs11078406 chr17:17840823 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.6 0.56 6.32e-12 Total body bone mineral density; TGCT cis rs739496 0.615 rs7978737 chr12:112196611 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.01 0.41 1.84e-6 Platelet count; TGCT cis rs2404602 0.735 rs3765115 chr15:76673716 T/C cg22467129 chr15:76604101 ETFA 0.46 4.68 0.39 7.38e-6 Blood metabolite levels; TGCT cis rs9291683 0.510 rs4318649 chr4:10016815 T/C cg00071950 chr4:10020882 SLC2A9 0.66 7.75 0.57 2.83e-12 Bone mineral density; TGCT cis rs11690935 1.000 rs6757773 chr2:172549630 T/A cg13550731 chr2:172543902 DYNC1I2 1.2 12.95 0.76 8.62e-25 Schizophrenia; TGCT cis rs10206020 0.885 rs11899557 chr2:1576123 G/T cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs12682352 0.602 rs1473029 chr8:8668917 A/C cg06636001 chr8:8085503 FLJ10661 0.6 5.07 0.41 1.43e-6 Neuroticism; TGCT cis rs6840360 0.615 rs12647586 chr4:152607568 G/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.13 -0.48 1.07e-8 Intelligence (multi-trait analysis); TGCT cis rs7246657 0.639 rs3112434 chr19:38198148 G/T cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs6586111 1.000 rs7915642 chr10:82377861 T/C cg03086067 chr10:82368399 SH2D4B -0.24 -4.71 -0.39 6.6e-6 Capecitabine sensitivity; TGCT cis rs367615 0.506 rs2963021 chr5:108800365 C/T cg17395555 chr5:108820864 NA 0.23 4.54 0.38 1.32e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6901250 0.587 rs339357 chr6:117198291 G/C cg12892004 chr6:117198278 RFX6 -0.57 -6.94 -0.53 1.92e-10 C-reactive protein levels; TGCT cis rs7666738 0.830 rs11944107 chr4:98931638 G/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7336332 0.598 rs9581850 chr13:28012265 A/G cg22138327 chr13:27999177 GTF3A 0.81 6.35 0.5 3.66e-9 Weight; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg06675538 chr2:114033490 PAX8;LOC440839 -0.44 -4.88 -0.4 3.18e-6 Lymphocyte counts; TGCT cis rs6952808 0.858 rs12671113 chr7:1965255 G/A cg22963979 chr7:1858916 MAD1L1 -0.35 -5.43 -0.44 2.9e-7 Bipolar disorder and schizophrenia; TGCT trans rs1499614 0.901 rs2178742 chr7:66197799 G/A cg07424592 chr7:64974309 NA 1.31 7.65 0.57 4.73e-12 Gout; TGCT cis rs10984561 0.881 rs10984554 chr9:122247659 A/G cg14242995 chr9:122249943 NA -0.75 -6.41 -0.5 2.7e-9 Pulmonary function decline; TGCT cis rs2851682 0.706 rs2524299 chr11:61604782 A/T cg20584555 chr11:61717780 BEST1 -0.32 -4.56 -0.38 1.21e-5 Gestational age at birth (child effect);Trans fatty acid levels; TGCT cis rs3008870 1.000 rs3008874 chr1:67431365 A/T cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs17001868 0.568 rs9611310 chr22:40733777 A/G cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs9914988 0.943 rs4795457 chr17:27087929 C/T cg20469991 chr17:27169893 C17orf63 -0.76 -5.56 -0.45 1.55e-7 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1023500 1.000 rs1023498 chr22:42340569 C/T cg04692870 chr22:42525206 CYP2D6 -0.33 -4.95 -0.41 2.37e-6 Schizophrenia; TGCT cis rs6484504 0.576 rs158144 chr11:31211795 A/C cg26647111 chr11:31128758 NA -0.34 -4.62 -0.38 9.36e-6 Red blood cell count; TGCT cis rs727505 1.000 rs68007199 chr7:124491307 T/C cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs35146811 0.735 rs2272344 chr7:99786819 C/T cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs7681440 0.804 rs1442135 chr4:90819093 C/T cg26578617 chr4:90757533 SNCA 0.45 4.89 0.4 3.04e-6 Dementia with Lewy bodies; TGCT cis rs3782455 1.000 rs76258123 chr12:114402449 G/C cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg23708337 chr7:1209742 NA 0.56 5.1 0.42 1.25e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4808199 0.895 rs6511036 chr19:19582651 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.15 0.42 9.94e-7 Nonalcoholic fatty liver disease; TGCT cis rs2692947 0.537 rs72821437 chr2:96200799 C/T cg23100626 chr2:96804247 ASTL 0.45 5.34 0.43 4.21e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs55823223 0.564 rs12103594 chr17:73855279 C/T cg10935138 chr17:73851978 WBP2 0.82 7.3 0.55 3.03e-11 Psoriasis; TGCT cis rs11030122 0.702 rs12281293 chr11:3963814 C/T cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 9.09 0.63 2.03e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg03517284 chr6:25882590 NA -1.08 -13.96 -0.78 3.4e-27 Urate levels; TGCT cis rs1941023 0.503 rs4939348 chr11:60135871 A/C cg08716584 chr11:60157161 MS4A7 -0.31 -4.56 -0.38 1.21e-5 Congenital heart disease (maternal effect); TGCT cis rs36051895 0.589 rs7869015 chr9:5199750 C/T cg02405213 chr9:5042618 JAK2 -0.76 -10.36 -0.68 1.68e-18 Pediatric autoimmune diseases; TGCT cis rs4654899 0.525 rs12035087 chr1:21471606 T/A cg01072550 chr1:21505969 NA 0.57 9.48 0.65 2.23e-16 Superior frontal gyrus grey matter volume; TGCT cis rs854765 0.616 rs8070624 chr17:17843396 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.65 6.36 0.5 3.58e-9 Total body bone mineral density; TGCT cis rs526231 0.781 rs2569015 chr5:102608847 A/G cg05225461 chr5:102596755 C5orf30 0.23 4.65 0.39 8.39e-6 Primary biliary cholangitis; TGCT cis rs7659604 0.702 rs58649165 chr4:122693752 C/A cg06713675 chr4:122721982 EXOSC9 -0.56 -7.58 -0.56 7.18e-12 Type 2 diabetes; TGCT cis rs7104764 0.957 rs6598064 chr11:243557 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs2172802 0.570 rs6820960 chr4:62518033 A/T cg04118610 chr4:62707027 LPHN3 -0.39 -4.58 -0.38 1.12e-5 Partial epilepsies; TGCT cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs6750795 0.569 rs1797387 chr2:232414692 A/G cg19187155 chr2:232395269 NMUR1 0.4 4.53 0.38 1.35e-5 Height; TGCT cis rs7249142 0.562 rs1050544 chr19:19287901 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.47 -4.83 -0.4 3.93e-6 IgG glycosylation; TGCT cis rs2760061 0.626 rs2527615 chr1:228119283 A/G cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg16325326 chr1:53192061 ZYG11B 0.7 8.23 0.59 2.19e-13 Monocyte count; TGCT cis rs832540 0.656 rs832567 chr5:56152416 C/A cg24531977 chr5:56204891 C5orf35 -0.54 -5.34 -0.43 4.33e-7 Coronary artery disease; TGCT cis rs12711979 0.765 rs13030772 chr2:3821280 T/C cg17052675 chr2:3827356 NA -0.4 -7.82 -0.57 2.02e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs1371867 0.875 rs1612773 chr8:101337818 G/C cg06636551 chr8:101224915 SPAG1 -0.44 -5.82 -0.46 4.61e-8 Atrioventricular conduction; TGCT cis rs763014 0.932 rs7204439 chr16:661335 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.41 -0.6 8.2e-14 Height; TGCT cis rs2688608 0.592 rs3849967 chr10:75483366 C/T cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs7635838 0.892 rs9838141 chr3:11488639 C/T cg00170343 chr3:11313890 ATG7 0.64 6.08 0.48 1.38e-8 HDL cholesterol; TGCT cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg01570182 chr17:44337453 NA 1.08 9.36 0.64 4.36e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4074961 0.604 rs4411102 chr1:38063424 C/G cg11397548 chr1:38022522 DNALI1 0.46 5.08 0.42 1.33e-6 Axial length; TGCT cis rs9911578 1.000 rs12940681 chr17:56933622 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.29 0.64 6.74e-16 Intelligence (multi-trait analysis); TGCT cis rs13082711 0.595 rs17317435 chr3:27339326 A/G cg02860705 chr3:27208620 NA 0.46 6.95 0.53 1.8e-10 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7246657 1.000 rs6508710 chr19:37749886 A/G cg24025825 chr19:37761650 NA -0.25 -4.53 -0.38 1.34e-5 Coronary artery calcification; TGCT cis rs13326165 0.760 rs11706108 chr3:52372366 T/C cg27565382 chr3:53032988 SFMBT1 0.38 5.06 0.41 1.5e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7752195 0.643 rs77951490 chr6:25236645 G/A cg16898833 chr6:26189333 HIST1H4D 0.97 4.58 0.38 1.1e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs651907 0.557 rs11924013 chr3:101366698 G/A cg12386194 chr3:101231763 SENP7 0.51 5.01 0.41 1.84e-6 Colorectal cancer; TGCT cis rs877282 0.733 rs11253342 chr10:765072 A/G cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs611744 0.967 rs682007 chr8:109210326 G/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7666738 0.830 rs60391193 chr4:98933912 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9400467 0.537 rs17663278 chr6:111504881 A/C cg15721981 chr6:111408429 SLC16A10 0.71 4.6 0.38 1.04e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs2413583 0.591 rs115263847 chr22:39729777 C/T cg24399712 chr22:39784796 NA 0.82 4.48 0.37 1.69e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs6879260 1.000 rs7730585 chr5:179733440 T/C cg23248424 chr5:179741104 GFPT2 -0.38 -7.07 -0.54 9.78e-11 Height; TGCT cis rs6121246 0.609 rs6060955 chr20:30385071 A/G cg13852791 chr20:30311386 BCL2L1 0.8 7.55 0.56 8.29e-12 Mean corpuscular hemoglobin; TGCT cis rs1538970 1.000 rs11211101 chr1:45849311 C/G cg05343316 chr1:45956843 TESK2 0.65 5.12 0.42 1.12e-6 Platelet count; TGCT cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.33e-9 Electroencephalogram traits; TGCT cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs881375 0.900 rs1008383 chr9:123683579 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.38 4.5 0.37 1.57e-5 Rheumatoid arthritis; TGCT cis rs9467711 0.606 rs9379855 chr6:26364930 C/T cg16898833 chr6:26189333 HIST1H4D -1.09 -5.27 -0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2307449 0.731 rs62020354 chr15:89818342 C/T cg24365117 chr15:89879190 POLG 0.33 4.6 0.38 1.01e-5 Menopause (age at onset); TGCT cis rs4665809 0.627 rs7562192 chr2:26469457 C/G cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs2075371 0.863 rs1421479 chr7:133949345 T/G cg11752832 chr7:134001865 SLC35B4 0.66 5.51 0.44 1.95e-7 Mean platelet volume; TGCT cis rs11098499 0.535 rs10005542 chr4:120268302 T/C cg09307838 chr4:120376055 NA 0.56 5.57 0.45 1.51e-7 Corneal astigmatism; TGCT cis rs55882075 0.723 rs56227602 chr5:179179472 A/G cg14593053 chr5:179126677 CANX 0.51 5.9 0.47 3.23e-8 Monocyte percentage of white cells; TGCT cis rs11190604 1.000 rs2495750 chr10:102327708 A/G cg23241863 chr10:102295624 HIF1AN 0.67 5.1 0.42 1.23e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg06112835 chr11:68658793 MRPL21 0.48 8.17 0.59 3.09e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7927592 0.763 rs2513277 chr11:68360887 T/G cg16797656 chr11:68205561 LRP5 0.25 4.5 0.37 1.53e-5 Total body bone mineral density; TGCT cis rs3784262 0.869 rs4646628 chr15:58255282 T/C cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.64 -0.57 5.03e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs5750830 0.649 rs5750820 chr22:39825322 T/G cg05872129 chr22:39784769 NA -0.98 -10.82 -0.7 1.27e-19 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.785 rs1057983 chr16:1660274 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.26 -4.52 -0.38 1.45e-5 Coronary artery disease; TGCT cis rs4849975 0.510 rs28548099 chr2:3710938 G/A cg21484315 chr2:2712669 NA -0.42 -4.96 -0.41 2.26e-6 Response to inhaled corticosteroid treatment in asthma (change in FEV1); TGCT cis rs72615157 0.634 rs74774557 chr7:99810425 A/G cg00814883 chr7:100076585 TSC22D4 -0.61 -5.66 -0.45 1.01e-7 Lung function (FEV1/FVC); TGCT cis rs6430585 0.528 rs6430594 chr2:136719173 C/T cg07169764 chr2:136633963 MCM6 -1.26 -12.74 -0.75 2.79e-24 Corneal structure; TGCT cis rs1903068 0.853 rs28838369 chr4:56007249 A/G cg09978860 chr4:56023921 NA 0.58 6.22 0.49 7.14e-9 Endometriosis; TGCT cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs12048904 0.595 rs10493937 chr1:101342650 A/T cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.62 -6.1 -0.48 1.24e-8 Multiple sclerosis; TGCT cis rs1488864 1.000 rs4758096 chr11:6348614 C/G cg12755421 chr11:6342214 PRKCDBP -0.56 -4.48 -0.37 1.7e-5 Smooth-surface caries; TGCT cis rs3099143 1.000 rs2046415 chr15:77085253 A/G cg21673338 chr15:77095150 SCAPER -0.53 -5.22 -0.42 7.33e-7 Recalcitrant atopic dermatitis; TGCT cis rs72843506 0.722 rs9897161 chr17:20034270 T/C cg18979559 chr17:20280153 CCDC144C -0.65 -4.87 -0.4 3.33e-6 Schizophrenia; TGCT cis rs4689388 0.819 rs12649341 chr4:6294759 G/A cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7113874 0.610 rs11041924 chr11:8463107 C/T cg14521421 chr11:8862019 ST5 0.29 4.5 0.37 1.54e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs986417 0.681 rs1254329 chr14:60912870 G/A cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs875971 0.862 rs6960446 chr7:65733259 A/G cg11764359 chr7:65958608 NA -0.54 -4.86 -0.4 3.45e-6 Aortic root size; TGCT cis rs7809950 0.817 rs58052742 chr7:107210003 A/G cg23024343 chr7:107201750 COG5 0.46 6.42 0.5 2.67e-9 Coronary artery disease; TGCT cis rs7010267 0.692 rs3102732 chr8:119960547 A/C cg17171407 chr8:119960777 TNFRSF11B 0.28 5.1 0.42 1.25e-6 Total body bone mineral density (age 45-60); TGCT cis rs12579753 0.879 rs7958566 chr12:82131478 A/T cg21231944 chr12:82153410 PPFIA2 -0.36 -4.7 -0.39 6.72e-6 Resting heart rate; TGCT cis rs1729951 0.575 rs2163896 chr3:136691177 G/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs9911578 1.000 rs4482353 chr17:56896834 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs854765 0.547 rs9896837 chr17:17924868 A/G cg04398451 chr17:18023971 MYO15A -0.32 -5.12 -0.42 1.15e-6 Total body bone mineral density; TGCT cis rs7208859 0.614 rs7216394 chr17:28825756 T/C cg13385521 chr17:29058706 SUZ12P -0.69 -4.57 -0.38 1.18e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2760061 0.819 rs3094913 chr1:228206980 T/C cg18477163 chr1:228402036 OBSCN 0.34 7.24 0.55 4.1e-11 Diastolic blood pressure; TGCT cis rs7959452 0.590 rs56054057 chr12:69775972 C/T cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs7567389 0.719 rs4150404 chr2:128050000 A/G cg09760422 chr2:128146352 NA -0.34 -4.45 -0.37 1.87e-5 Self-rated health; TGCT cis rs66561647 0.597 rs34390452 chr8:128940141 G/A cg11792826 chr8:129160931 MIR1208 0.23 5.22 0.42 7.31e-7 Hemoglobin concentration; TGCT trans rs4919669 0.719 rs17114803 chr10:104386934 A/G cg24066601 chr6:26271455 HIST1H3G 0.66 6.81 0.52 3.7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs7412746 0.658 rs10305714 chr1:150800655 C/T cg04414720 chr1:150670196 GOLPH3L -0.36 -4.6 -0.38 1.04e-5 Melanoma; TGCT cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.69 0.62 1.83e-14 Platelet count; TGCT cis rs9894429 0.634 rs9709130 chr17:79583948 C/T cg21028142 chr17:79581711 NPLOC4 0.29 5.95 0.47 2.56e-8 Eye color traits; TGCT cis rs3812831 0.695 rs423237 chr13:114930955 C/T cg08824895 chr13:115047677 UPF3A 0.51 4.98 0.41 2.07e-6 Schizophrenia; TGCT cis rs904251 0.523 rs2797794 chr6:37480604 T/C cg08126542 chr6:37504118 NA -0.46 -6.64 -0.51 8.96e-10 Cognitive performance; TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg18081338 chr6:17212963 NA 0.55 5.58 0.45 1.43e-7 Gambling; TGCT cis rs875971 0.965 rs7794930 chr7:65778546 A/C cg11764359 chr7:65958608 NA -0.62 -5.53 -0.44 1.81e-7 Aortic root size; TGCT cis rs6089584 0.627 rs55875402 chr20:60559925 G/A cg06108461 chr20:60628389 TAF4 -0.4 -4.8 -0.4 4.4e-6 Body mass index; TGCT cis rs4478858 0.735 rs7523438 chr1:31788313 C/T cg00250761 chr1:31883323 NA 0.27 4.82 0.4 4.15e-6 Alcohol dependence; TGCT cis rs7666738 0.830 rs13118892 chr4:98968497 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs80282103 0.717 rs41299206 chr10:1120236 T/C cg18964960 chr10:1102726 WDR37 0.98 4.47 0.37 1.71e-5 Glomerular filtration rate (creatinine); TGCT cis rs12477438 0.765 rs2167930 chr2:99592551 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg26338869 chr17:61819248 STRADA -0.52 -4.86 -0.4 3.52e-6 Prudent dietary pattern; TGCT cis rs6921919 0.583 rs7740351 chr6:28399412 A/C cg18815343 chr6:28367644 ZSCAN12 -0.55 -5.16 -0.42 9.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs912057 0.671 rs1024246 chr6:6743505 A/T cg06612196 chr6:6737390 NA 0.48 6.95 0.53 1.82e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs7666738 0.830 rs1426664 chr4:98988264 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs1371867 0.846 rs1788180 chr8:101333368 A/G cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs7954584 0.567 rs7132055 chr12:122346034 A/G cg21016266 chr12:122356598 WDR66 -0.52 -6.5 -0.5 1.75e-9 Mean corpuscular volume; TGCT cis rs875971 0.964 rs778735 chr7:65814809 C/A cg18876405 chr7:65276391 NA 0.32 4.93 0.4 2.61e-6 Aortic root size; TGCT cis rs79149102 0.579 rs6495137 chr15:75295541 G/A cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs9487051 0.872 rs9487043 chr6:109610474 C/T cg01475377 chr6:109611718 NA -0.3 -4.68 -0.39 7.46e-6 Reticulocyte fraction of red cells; TGCT cis rs10927875 0.632 rs4661667 chr1:16162731 C/T cg21385522 chr1:16154831 NA -1.0 -17.73 -0.85 8.56e-36 Dilated cardiomyopathy; TGCT cis rs9916302 0.904 rs7223438 chr17:37521355 T/C cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs7552404 0.824 rs1251077 chr1:76189745 C/G cg10523679 chr1:76189770 ACADM -0.98 -14.22 -0.79 8.25e-28 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2544527 0.819 rs2544523 chr2:15920323 T/C cg26669897 chr2:15909070 NA 0.42 4.98 0.41 2.09e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs2980439 0.557 rs2921056 chr8:8319182 T/C cg08975724 chr8:8085496 FLJ10661 0.6 5.45 0.44 2.59e-7 Neuroticism; TGCT cis rs67311347 1.000 rs9829800 chr3:40443927 T/C cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg07507251 chr3:52567010 NT5DC2 0.51 7.63 0.57 5.48e-12 Electroencephalogram traits; TGCT cis rs707040 0.961 rs10210987 chr2:155233967 G/A cg18104148 chr2:154337490 NA 0.19 4.57 0.38 1.17e-5 Sudden cardiac arrest; TGCT cis rs1215050 0.791 rs165237 chr4:98712029 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11696501 0.688 rs6124727 chr20:44325623 T/C cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg03303774 chr4:1407052 NA 0.31 4.96 0.41 2.25e-6 Obesity-related traits; TGCT cis rs3905510 0.658 rs17150506 chr5:122943848 A/G cg15125798 chr5:122621645 NA 0.55 4.94 0.41 2.5e-6 Total body bone mineral density; TGCT cis rs6500602 0.826 rs9925719 chr16:4461861 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.45 5.75 0.46 6.66e-8 Schizophrenia; TGCT cis rs1048238 0.846 rs945419 chr1:16344858 C/T cg21385522 chr1:16154831 NA 0.43 4.52 0.38 1.43e-5 Systolic blood pressure; TGCT cis rs904251 0.600 rs12211110 chr6:37466232 A/G cg25019722 chr6:37503610 NA -0.49 -7.08 -0.54 9.21e-11 Cognitive performance; TGCT cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg11494091 chr17:61959527 GH2 0.43 7.47 0.56 1.23e-11 Height; TGCT cis rs1729951 0.575 rs361248 chr3:136709066 G/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.24e-7 Neuroticism; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg25767906 chr1:53392781 SCP2 0.49 5.64 0.45 1.09e-7 Monocyte count; TGCT cis rs7843479 0.562 rs2127206 chr8:21786989 C/T cg17168535 chr8:21777572 XPO7 0.92 9.4 0.65 3.52e-16 Mean corpuscular volume; TGCT cis rs3125734 0.633 rs4979772 chr10:63967600 C/T cg05499367 chr10:63213510 TMEM26 0.35 4.75 0.39 5.57e-6 Rheumatoid arthritis; TGCT cis rs2832191 0.740 rs2832175 chr21:30475606 A/G cg24692254 chr21:30365293 RNF160 -1.03 -12.06 -0.73 1.25e-22 Dental caries; TGCT cis rs6988636 1.000 rs13260775 chr8:124190167 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs2594989 0.943 rs2606748 chr3:11373989 T/C cg00170343 chr3:11313890 ATG7 0.67 4.99 0.41 2.04e-6 Circulating chemerin levels; TGCT cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs2836974 0.830 rs2735309 chr21:40715313 C/T cg06238570 chr21:40685208 BRWD1 0.67 5.84 0.46 4.4e-8 Cognitive function; TGCT cis rs2455601 0.638 rs2568092 chr11:8987438 A/G cg09997546 chr11:8931473 C11orf17;ST5 0.44 4.53 0.38 1.38e-5 Schizophrenia; TGCT cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg11644478 chr21:40555479 PSMG1 -0.63 -5.93 -0.47 2.79e-8 Cognitive function; TGCT cis rs597539 0.652 rs613128 chr11:68638058 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12200560 0.505 rs4839849 chr6:97076673 T/C cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs7833790 0.724 rs6473310 chr8:82707981 A/G cg17211192 chr8:82754475 SNX16 -0.93 -8.71 -0.62 1.62e-14 Diastolic blood pressure; TGCT cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg16497277 chr3:49208875 KLHDC8B -0.6 -5.62 -0.45 1.21e-7 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs1008375 1.000 rs3815414 chr4:17606659 A/G cg18681998 chr4:17616180 MED28 -0.97 -10.99 -0.7 5.01e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2847297 1.000 rs2847297 chr18:12797694 A/G cg23544223 chr18:12777786 NA -0.4 -4.77 -0.39 5.12e-6 Rheumatoid arthritis; TGCT cis rs9527 0.615 rs4919685 chr10:104587362 G/T cg15744005 chr10:104629667 AS3MT -0.46 -5.59 -0.45 1.38e-7 Arsenic metabolism; TGCT cis rs62244186 0.659 rs6441844 chr3:44503579 C/T cg02073558 chr3:44770973 ZNF501 0.61 5.79 0.46 5.34e-8 Depressive symptoms; TGCT cis rs9916302 0.861 rs752314 chr17:37410700 C/T cg15445000 chr17:37608096 MED1 0.33 4.84 0.4 3.8e-6 Glomerular filtration rate (creatinine); TGCT cis rs7772486 0.754 rs13214277 chr6:146136125 G/T cg05347473 chr6:146136440 FBXO30 0.54 5.11 0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10875746 0.903 rs11168370 chr12:48435280 A/C cg20731937 chr12:48336164 NA 0.58 4.79 0.4 4.66e-6 Longevity (90 years and older); TGCT cis rs6882046 0.513 rs639725 chr5:88001969 A/G cg24804195 chr5:87968844 LOC645323 -0.59 -5.71 -0.46 7.96e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2249625 0.844 rs1015944 chr6:72925747 A/G cg24401219 chr6:72892597 RIMS1 -0.56 -4.51 -0.38 1.47e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs11734570 0.581 rs4461531 chr4:38603576 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.61 5.21 0.42 7.55e-7 Inflammatory bowel disease;Crohn's disease; TGCT cis rs2637266 1.000 rs1907317 chr10:78337849 C/A cg18941641 chr10:78392320 NA 0.4 4.93 0.41 2.54e-6 Pulmonary function; TGCT cis rs7714584 1.000 rs2345001 chr5:150266518 G/T cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs9341808 0.718 rs9359408 chr6:80820132 T/G cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs9381040 0.610 rs2235679 chr6:41020577 G/T cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT cis rs7772486 0.658 rs9403737 chr6:145962193 G/T cg13319975 chr6:146136371 FBXO30 -0.53 -4.85 -0.4 3.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs231513 0.871 rs231522 chr17:41954602 A/G cg26893861 chr17:41843967 DUSP3 -0.78 -5.58 -0.45 1.47e-7 Cognitive function; TGCT cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs28595532 0.920 rs56046676 chr4:119766733 A/G cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs9291683 0.507 rs3796837 chr4:10011321 C/G cg00071950 chr4:10020882 SLC2A9 0.63 7.37 0.55 2.12e-11 Bone mineral density; TGCT cis rs1865760 0.566 rs1971509 chr6:26085777 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs832540 0.618 rs2548663 chr5:56172778 G/A cg12311346 chr5:56204834 C5orf35 -0.49 -5.05 -0.41 1.55e-6 Coronary artery disease; TGCT cis rs7659604 0.502 rs11098640 chr4:122675875 G/A cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs1218582 0.772 rs4240874 chr1:154885779 C/T cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs67311347 1.000 rs11720360 chr3:40448397 G/A cg13683864 chr3:40499215 RPL14 -1.19 -13.15 -0.76 2.94e-25 Renal cell carcinoma; TGCT cis rs4819052 0.580 rs419322 chr21:46551702 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.66 5.18 0.42 8.61e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9291683 0.588 rs3796829 chr4:10019138 C/G cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Bone mineral density; TGCT cis rs1865760 0.865 rs9467647 chr6:25957642 A/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs2549003 1.000 rs2070726 chr5:131821738 C/A cg02551604 chr5:131831745 NA -0.9 -12.1 -0.74 9.75e-23 Asthma (sex interaction); TGCT cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg24829409 chr8:58192753 C8orf71 -0.54 -4.8 -0.4 4.42e-6 Developmental language disorder (linguistic errors); TGCT cis rs4253772 0.550 rs6007818 chr22:46703776 C/T cg24881330 chr22:46731750 TRMU 1.03 5.38 0.43 3.61e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9814567 1.000 rs2373865 chr3:134291556 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs270601 0.837 rs367805 chr5:131701279 T/C cg16647868 chr5:131706066 SLC22A5 0.31 4.48 0.37 1.67e-5 Acylcarnitine levels; TGCT cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.53 4.48 0.37 1.65e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs727505 0.954 rs1568883 chr7:124710761 G/A cg23710748 chr7:124431027 NA -0.27 -4.59 -0.38 1.07e-5 Lewy body disease; TGCT cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs274567 0.501 rs272855 chr5:131687175 C/T cg24060327 chr5:131705240 SLC22A5 -0.75 -8.12 -0.59 3.87e-13 Blood metabolite levels; TGCT cis rs250677 0.522 rs55732303 chr5:148392538 C/T cg18129178 chr5:148520854 ABLIM3 -0.35 -4.58 -0.38 1.12e-5 Breast cancer; TGCT cis rs138491296 1 rs138491296 chr17:27961561 GATTATT/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.93 -9.13 -0.63 1.58e-15 White blood cell count; TGCT cis rs6754311 0.608 rs3739020 chr2:136602491 T/G cg07169764 chr2:136633963 MCM6 0.77 7.06 0.54 1.06e-10 Mosquito bite size; TGCT cis rs9807989 0.839 rs4988955 chr2:102967928 A/G cg09003973 chr2:102972529 NA 0.59 5.21 0.42 7.58e-7 Asthma; TGCT cis rs2945232 1 rs2945232 chr8:8098038 T/C cg08975724 chr8:8085496 FLJ10661 0.63 5.81 0.46 4.85e-8 Schizophrenia; TGCT cis rs2777491 1.000 rs7167729 chr15:41721042 G/A cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.01 -0.7 4.47e-20 Ulcerative colitis; TGCT cis rs797680 0.856 rs10874764 chr1:93661342 C/A cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.89e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs832540 0.669 rs173764 chr5:56198920 C/T cg20203395 chr5:56204925 C5orf35 -0.54 -4.86 -0.4 3.42e-6 Coronary artery disease; TGCT cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs12762955 0.561 rs11253567 chr10:1054444 A/G cg18964960 chr10:1102726 WDR37 0.67 5.84 0.46 4.3e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs6964587 0.626 rs4729014 chr7:91550707 A/G cg17063962 chr7:91808500 NA -0.76 -7.25 -0.55 3.94e-11 Breast cancer; TGCT cis rs66573146 0.901 rs55659111 chr4:7012338 G/T cg05069807 chr4:6945702 TBC1D14 0.41 5.42 0.44 3.05e-7 Granulocyte percentage of myeloid white cells; TGCT trans rs2970818 0.831 rs7304949 chr12:4609625 A/G cg11755803 chr12:129000542 TMEM132C 0.52 6.84 0.52 3.22e-10 Phosphorus levels; TGCT cis rs6988636 0.584 rs75096144 chr8:124131225 C/T cg27053337 chr8:124217698 FAM83A 0.54 4.69 0.39 7.01e-6 Urinary uromodulin levels; TGCT cis rs6591182 0.504 rs7130955 chr11:65372580 C/T cg17480646 chr11:65405466 SIPA1 -0.52 -6.73 -0.52 5.48e-10 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg12386194 chr3:101231763 SENP7 0.52 4.92 0.4 2.68e-6 Colorectal cancer; TGCT cis rs7819412 0.642 rs11250117 chr8:10972740 C/A cg21775007 chr8:11205619 TDH -0.49 -4.77 -0.39 5e-6 Triglycerides; TGCT cis rs2658782 1.000 rs2605582 chr11:93163799 C/T cg18152523 chr11:93063302 CCDC67 -0.65 -5.27 -0.43 5.74e-7 Pulmonary function decline; TGCT cis rs1552244 0.882 rs13089863 chr3:10032259 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 0.45 6.71 0.52 6.15e-10 Alzheimer's disease; TGCT trans rs28735056 1.000 rs4798923 chr18:77629373 G/A cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT cis rs11105298 0.891 rs10858889 chr12:89902604 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg06634786 chr22:41940651 POLR3H -0.89 -8.27 -0.6 1.71e-13 Vitiligo; TGCT cis rs1903068 0.785 rs12331538 chr4:55998086 A/C cg01777861 chr4:56023843 NA 0.55 6.37 0.5 3.34e-9 Endometriosis; TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg16325326 chr1:53192061 ZYG11B 0.59 6.94 0.53 1.89e-10 Monocyte count; TGCT cis rs2346177 1.000 rs11125074 chr2:46655260 G/A cg26688816 chr2:46740690 ATP6V1E2 -0.45 -5.1 -0.42 1.24e-6 HDL cholesterol; TGCT cis rs7786808 0.552 rs2878456 chr7:158182129 A/T cg01191920 chr7:158217561 PTPRN2 -0.34 -5.06 -0.41 1.45e-6 Obesity-related traits; TGCT cis rs1372520 0.684 rs2619347 chr4:90745770 G/A cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs7511006 1.000 rs5771109 chr22:50678571 T/C cg08875078 chr22:50639485 SELO 0.52 5.11 0.42 1.2e-6 Obesity-related traits; TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg01802117 chr1:53393560 SCP2 -0.42 -4.86 -0.4 3.45e-6 Monocyte count; TGCT cis rs919433 0.617 rs700643 chr2:198601370 A/G cg00792783 chr2:198669748 PLCL1 0.55 4.96 0.41 2.29e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs7100689 0.646 rs7894762 chr10:82086779 C/G cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg23708337 chr7:1209742 NA 0.6 5.56 0.45 1.58e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg03188948 chr7:1209495 NA 0.43 5.67 0.45 9.5e-8 Longevity;Endometriosis; TGCT cis rs6570726 0.935 rs400968 chr6:145819718 A/G cg23711669 chr6:146136114 FBXO30 0.69 6.22 0.49 6.89e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.525 rs1535274 chr6:26520747 A/C cg05738196 chr6:26577821 NA 0.75 9.2 0.64 1.09e-15 Intelligence (multi-trait analysis); TGCT cis rs12464483 0.524 rs1348898 chr2:30888026 C/A cg17749961 chr2:30669863 LCLAT1 0.59 4.58 0.38 1.12e-5 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs10791097 0.592 rs7116068 chr11:130732739 A/C cg05962950 chr11:130786565 SNX19 -0.9 -11.73 -0.73 7.96e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs807669 0.742 rs1206544 chr22:19215039 C/T cg02655711 chr22:19163373 SLC25A1 0.33 7.25 0.55 3.9e-11 Metabolite levels; TGCT cis rs12134245 0.719 rs61798831 chr1:91996588 C/T cg25838465 chr1:92012736 NA -0.41 -6.57 -0.51 1.23e-9 Breast cancer; TGCT cis rs12510870 0.599 rs10029673 chr4:74451917 G/A cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs2075371 0.897 rs10488428 chr7:133997560 C/T cg11752832 chr7:134001865 SLC35B4 0.67 5.96 0.47 2.46e-8 Mean platelet volume; TGCT cis rs7666738 0.924 rs62318940 chr4:99064768 C/T cg05340658 chr4:99064831 C4orf37 0.49 4.75 0.39 5.56e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7959452 0.868 rs10878967 chr12:69740869 T/C cg11871910 chr12:69753446 YEATS4 0.76 8.31 0.6 1.44e-13 Blood protein levels; TGCT cis rs7647973 1.000 rs6783003 chr3:49524778 G/C cg07636037 chr3:49044803 WDR6 -0.73 -5.87 -0.47 3.65e-8 Menarche (age at onset); TGCT cis rs7726839 0.540 rs4957081 chr5:646418 G/C cg16624210 chr5:671434 TPPP 0.4 4.52 0.38 1.44e-5 Obesity-related traits; TGCT cis rs2486288 0.656 rs2413774 chr15:45549423 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT trans rs17685 0.753 rs2108274 chr7:75781636 C/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.59 0.61 3.07e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs4561483 0.549 rs154149 chr16:11956118 T/A cg08843971 chr16:11963173 GSPT1 -0.25 -4.55 -0.38 1.24e-5 Testicular germ cell tumor; TGCT cis rs4908768 0.512 rs4908784 chr1:8900568 C/T cg13202082 chr1:9882851 CLSTN1 0.34 4.5 0.37 1.54e-5 Neuroticism (multi-trait analysis);Subjective well-being (multi-trait analysis); TGCT cis rs7017914 0.905 rs2639896 chr8:71920783 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs2243480 1.000 rs778704 chr7:65863467 T/C cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs2115630 0.641 rs11073613 chr15:85185893 G/A cg12501888 chr15:85177176 SCAND2 -0.47 -4.48 -0.37 1.69e-5 P wave terminal force; TGCT cis rs6964587 0.869 rs10242792 chr7:91492103 A/C cg17063962 chr7:91808500 NA 0.87 9.22 0.64 9.9e-16 Breast cancer; TGCT cis rs4372836 0.681 rs4477866 chr2:29009089 C/A cg09522027 chr2:28974177 PPP1CB -0.64 -6.42 -0.5 2.68e-9 Body mass index; TGCT trans rs34421088 0.559 rs12386974 chr8:11400628 C/G cg15556689 chr8:8085844 FLJ10661 0.78 7.88 0.58 1.46e-12 Neuroticism; TGCT cis rs76878669 0.606 rs2282531 chr11:66099494 C/T cg18002602 chr11:66138449 SLC29A2 -0.52 -6.47 -0.5 2.06e-9 Educational attainment (years of education); TGCT cis rs9357506 1.000 rs9296492 chr6:46315573 A/G cg21115430 chr6:46460003 NA 0.25 5.1 0.42 1.26e-6 Body mass index; TGCT cis rs79387448 0.655 rs77763678 chr2:102916749 G/A cg09003973 chr2:102972529 NA 1.34 8.26 0.6 1.89e-13 Gut microbiota (bacterial taxa); TGCT cis rs7666738 0.830 rs6832209 chr4:98994120 A/G cg05340658 chr4:99064831 C4orf37 0.49 5.6 0.45 1.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs7726839 0.540 rs58599998 chr5:596087 A/G cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs12142240 0.660 rs112560929 chr1:46822297 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT trans rs1814175 0.817 rs7950856 chr11:49976394 C/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs477895 0.838 rs7111278 chr11:64016284 G/A cg04317338 chr11:64019027 PLCB3 0.81 6.9 0.53 2.35e-10 Mean platelet volume; TGCT cis rs765787 0.530 rs13329228 chr15:45533017 C/T cg24006582 chr15:45444508 DUOX1 -0.24 -5.28 -0.43 5.51e-7 Uric acid levels; TGCT cis rs7809950 1.000 rs2520268 chr7:107191161 T/A cg23024343 chr7:107201750 COG5 -0.35 -5.36 -0.43 3.99e-7 Coronary artery disease; TGCT cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs35883536 0.967 rs1981134 chr1:101111205 G/T cg06223162 chr1:101003688 GPR88 -0.28 -4.56 -0.38 1.22e-5 Monocyte count; TGCT cis rs2067615 0.579 rs66716938 chr12:107196825 T/C cg15890332 chr12:107067104 RFX4 0.28 5.61 0.45 1.27e-7 Heart rate; TGCT cis rs10114408 0.959 rs10992960 chr9:96653178 A/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6840360 0.615 rs10021407 chr4:152465002 A/G cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs10779751 1.000 rs11121710 chr1:11313244 T/C cg08854313 chr1:11322531 MTOR 0.95 8.63 0.61 2.54e-14 Body mass index; TGCT cis rs4689388 0.856 rs10016157 chr4:6294414 T/C cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7647973 1.000 rs74471041 chr3:49542543 T/G cg05785598 chr3:49045655 WDR6 -0.38 -4.5 -0.37 1.57e-5 Menarche (age at onset); TGCT cis rs597539 0.652 rs673821 chr11:68678718 G/T cg06028808 chr11:68637592 NA 0.5 6.59 0.51 1.12e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11718455 0.960 rs34019365 chr3:44004735 G/A cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs9916302 0.800 rs9892675 chr17:37549200 C/T cg15445000 chr17:37608096 MED1 -0.34 -4.84 -0.4 3.75e-6 Glomerular filtration rate (creatinine); TGCT cis rs76878669 0.561 rs2279862 chr11:66135179 C/T cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.89e-9 Educational attainment (years of education); TGCT cis rs6598955 0.670 rs7531518 chr1:26539749 T/C cg04990556 chr1:26633338 UBXN11 -0.89 -11.24 -0.71 1.2e-20 Obesity-related traits; TGCT cis rs1577917 0.545 rs9344548 chr6:86487337 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.6 4.94 0.41 2.47e-6 Response to antipsychotic treatment; TGCT cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg26531700 chr6:26746687 NA 0.66 6.42 0.5 2.68e-9 Intelligence (multi-trait analysis); TGCT cis rs7095607 0.606 rs10998015 chr10:69959624 A/G cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs4660261 0.526 rs2040950 chr1:44315113 G/C cg12908607 chr1:44402522 ARTN -0.64 -7.66 -0.57 4.69e-12 Intelligence (multi-trait analysis); TGCT cis rs3617 0.573 rs9860296 chr3:52913781 A/G cg10802521 chr3:52805072 NEK4 -0.56 -6.4 -0.5 2.87e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs131777 0.708 rs131749 chr22:51024624 C/T cg25309564 chr22:51001381 C22orf41 -0.53 -4.96 -0.41 2.23e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7267979 0.873 rs6083853 chr20:25404541 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs611744 0.967 rs688746 chr8:109225725 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs9467711 1.000 rs6923139 chr6:26313348 C/T cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs938554 0.558 rs4697701 chr4:9946095 C/T cg11266682 chr4:10021025 SLC2A9 -0.47 -5.03 -0.41 1.67e-6 Blood metabolite levels; TGCT cis rs903263 0.965 rs11163905 chr1:84594399 C/T cg09664975 chr1:84543551 PRKACB 0.48 4.56 0.38 1.19e-5 Breast cancer (male); TGCT cis rs478607 0.764 rs2666558 chr11:64481579 G/A cg19395706 chr11:64412079 NRXN2 -0.47 -5.02 -0.41 1.73e-6 Urate levels; TGCT cis rs11673344 0.523 rs8110158 chr19:37554393 C/A cg08039142 chr19:36980659 ZNF566 0.5 4.64 0.38 8.63e-6 Obesity-related traits; TGCT cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs1371867 0.846 rs2919469 chr8:101233896 C/T cg06002616 chr8:101225028 SPAG1 -0.54 -6.46 -0.5 2.15e-9 Atrioventricular conduction; TGCT cis rs7666738 0.830 rs13118945 chr4:98968586 T/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg21724239 chr8:58056113 NA 0.41 4.87 0.4 3.33e-6 Developmental language disorder (linguistic errors); TGCT cis rs938554 0.513 rs3775948 chr4:9995182 G/C cg11266682 chr4:10021025 SLC2A9 0.54 4.8 0.4 4.55e-6 Blood metabolite levels; TGCT cis rs7954584 0.545 rs12824593 chr12:122374108 G/A cg13699009 chr12:122356056 WDR66 0.29 5.72 0.46 7.44e-8 Mean corpuscular volume; TGCT cis rs514406 0.584 rs7524702 chr1:53197830 G/A cg22166914 chr1:53195759 ZYG11B -0.5 -9.4 -0.65 3.56e-16 Monocyte count; TGCT cis rs1552244 1.000 rs34179822 chr3:10140017 A/G cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg09222892 chr1:25734099 RHCE -0.41 -6.8 -0.52 3.99e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs7909074 1.000 rs1408814 chr10:45399088 A/G cg04218760 chr10:45406644 TMEM72 -0.27 -5.38 -0.44 3.57e-7 Mean corpuscular volume; TGCT cis rs7267979 0.903 rs2500400 chr20:25354705 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6141769 0.518 rs6058834 chr20:31316862 C/T cg13636640 chr20:31349939 DNMT3B -0.52 -4.54 -0.38 1.34e-5 Subjective well-being; TGCT trans rs9329221 0.617 rs483916 chr8:9793601 A/C cg15556689 chr8:8085844 FLJ10661 -0.81 -8.68 -0.61 1.93e-14 Neuroticism; TGCT cis rs12579753 0.827 rs7311917 chr12:82187551 G/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs4906332 1.000 rs3783397 chr14:103947289 A/G cg26031613 chr14:104095156 KLC1 -0.53 -4.86 -0.4 3.42e-6 Coronary artery disease; TGCT cis rs9303401 0.659 rs12150264 chr17:56939927 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs12477438 0.798 rs6704766 chr2:99642818 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs1568889 0.838 rs11030230 chr11:28174631 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 11.12 0.71 2.31e-20 Bipolar disorder; TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg27535305 chr1:53392650 SCP2 -0.27 -5.29 -0.43 5.24e-7 Monocyte count; TGCT cis rs1552244 0.882 rs13064570 chr3:9997545 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 6.39 0.5 3.08e-9 Alzheimer's disease; TGCT cis rs875971 0.638 rs10249404 chr7:66046724 G/A cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs909674 0.818 rs7364148 chr22:39842165 T/C cg11247378 chr22:39784982 NA -0.71 -8.33 -0.6 1.25e-13 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg09359103 chr1:154839909 KCNN3 0.66 12.26 0.74 3.95e-23 Prostate cancer; TGCT cis rs875971 1.000 rs1544549 chr7:66090663 T/A cg11764359 chr7:65958608 NA -0.59 -5.2 -0.42 8.12e-7 Aortic root size; TGCT cis rs11264213 0.901 rs72661641 chr1:36448130 A/G cg27506609 chr1:36549197 TEKT2 0.41 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs1903068 0.925 rs1551643 chr4:55994226 T/A cg09978860 chr4:56023921 NA 0.58 6.38 0.5 3.16e-9 Endometriosis; TGCT cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg12310025 chr6:25882481 NA -0.51 -5.25 -0.43 6.43e-7 Height; TGCT cis rs4727027 0.866 rs3927307 chr7:148774869 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.99 0.41 2.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.07e-9 Type 2 diabetes; TGCT cis rs77972916 0.536 rs7589361 chr2:43589328 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.09 -0.48 1.3e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs4819052 0.959 rs8130866 chr21:46672112 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 5.44 0.44 2.76e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9341808 0.718 rs2179842 chr6:80979053 T/C cg08355045 chr6:80787529 NA 0.29 4.99 0.41 2.03e-6 Sitting height ratio; TGCT cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs8014204 0.967 rs4903266 chr14:75344941 C/G cg06637938 chr14:75390232 RPS6KL1 -0.74 -7.12 -0.54 7.82e-11 Caffeine consumption; TGCT cis rs12477438 0.520 rs11883676 chr2:99800814 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs854765 0.964 rs854762 chr17:18009102 G/A cg04398451 chr17:18023971 MYO15A 0.3 4.79 0.39 4.75e-6 Total body bone mineral density; TGCT cis rs6964587 1.000 rs7797834 chr7:91743150 C/T cg17063962 chr7:91808500 NA -0.9 -9.76 -0.66 4.92e-17 Breast cancer; TGCT cis rs4665630 0.522 rs4665235 chr2:23878102 C/G cg08063864 chr2:24346004 PFN4;LOC375190 -1.25 -5.71 -0.46 7.73e-8 Hypertension; TGCT cis rs2692947 0.567 rs4907276 chr2:96391109 G/T cg23100626 chr2:96804247 ASTL -0.44 -5.41 -0.44 3.19e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4886920 0.563 rs8037968 chr15:78077762 C/T cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.37e-6 Neuroticism; TGCT cis rs11098499 0.754 rs4107728 chr4:120253910 G/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs11711311 1.000 rs3773682 chr3:113520576 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.64 -0.51 8.96e-10 IgG glycosylation; TGCT cis rs62103177 0.608 rs4799115 chr18:77736365 A/T cg07235805 chr18:78004237 PARD6G -0.5 -4.9 -0.4 2.98e-6 Opioid sensitivity; TGCT cis rs7267979 0.934 rs6037085 chr20:25305202 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs875971 0.964 rs55748098 chr7:65763618 T/C cg11764359 chr7:65958608 NA -0.61 -5.36 -0.43 3.96e-7 Aortic root size; TGCT cis rs13108904 0.560 rs11247994 chr4:1343720 G/A cg00684032 chr4:1343700 KIAA1530 0.24 5.01 0.41 1.83e-6 Obesity-related traits; TGCT cis rs7412746 0.611 rs12410869 chr1:150856153 G/T cg04414720 chr1:150670196 GOLPH3L 0.4 4.82 0.4 4.06e-6 Melanoma; TGCT cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg05368731 chr17:41323189 NBR1 1.16 13.76 0.78 1.03e-26 Menopause (age at onset); TGCT cis rs9942416 0.660 rs61173369 chr5:74997995 A/G cg19683494 chr5:74908142 NA 0.57 6.37 0.5 3.33e-9 Age-related disease endophenotypes; TGCT cis rs2816062 0.813 rs2816053 chr1:18895819 A/G cg18795169 chr1:18902165 NA -0.58 -13.28 -0.77 1.36e-25 Urate levels in lean individuals; TGCT cis rs6570726 0.755 rs2092297 chr6:145893765 A/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1568889 0.877 rs7933326 chr11:28288416 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 7.87 0.58 1.54e-12 Bipolar disorder; TGCT cis rs7666738 0.830 rs17486413 chr4:99060544 G/T cg05340658 chr4:99064831 C4orf37 0.5 5.67 0.45 9.63e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9796 0.689 rs28497404 chr15:41449510 A/C cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.76 -0.52 4.71e-10 Menopause (age at onset); TGCT cis rs5769765 0.862 rs138857 chr22:50199589 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.07 -10.91 -0.7 7.73e-20 Schizophrenia; TGCT cis rs17607347 0.542 rs62051133 chr16:72466151 C/T cg06220725 chr16:72042591 DHODH -0.74 -4.83 -0.4 3.94e-6 Intelligence (multi-trait analysis); TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg09436375 chr6:42928200 GNMT -0.43 -5.55 -0.45 1.63e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6540559 0.932 rs764093 chr1:209983331 A/G cg04352962 chr1:209979756 IRF6 0.64 4.89 0.4 3.12e-6 Cleft lip with or without cleft palate; TGCT cis rs9527 0.590 rs10509764 chr10:104776475 G/A cg04362960 chr10:104952993 NT5C2 0.65 5.54 0.45 1.73e-7 Arsenic metabolism; TGCT cis rs380904 1.000 rs12543128 chr8:144595042 G/A cg09317036 chr8:144635547 GSDMD 0.5 4.77 0.39 5.06e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg10295955 chr4:187884368 NA -0.95 -14.86 -0.8 2.58e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs4455778 0.659 rs7808091 chr7:49071344 A/G cg26309511 chr7:48887640 NA 0.51 4.57 0.38 1.14e-5 Lung cancer in never smokers; TGCT cis rs9583531 0.509 rs9521923 chr13:111405462 C/T cg24331049 chr13:111365604 ING1 -0.84 -5.68 -0.45 9.25e-8 Coronary artery disease; TGCT cis rs7568458 0.837 rs6547624 chr2:85802134 A/T cg02493740 chr2:85810744 VAMP5 -0.27 -4.83 -0.4 4e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6121246 0.909 rs6089058 chr20:30326338 T/G cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs9443189 0.526 rs9359124 chr6:76200514 G/A cg01950844 chr6:76311363 SENP6 0.96 5.81 0.46 4.91e-8 Prostate cancer; TGCT cis rs4148883 0.504 rs4585310 chr4:100120233 T/C cg12011299 chr4:100065546 ADH4 -0.35 -5.04 -0.41 1.57e-6 Alcohol dependence; TGCT cis rs926938 0.563 rs360655 chr1:115447867 T/C cg12756093 chr1:115239321 AMPD1 0.4 6.33 0.49 4.02e-9 Autism; TGCT cis rs6977660 0.562 rs2189566 chr7:19768960 G/A cg07541023 chr7:19748670 TWISTNB 1.01 6.64 0.51 8.88e-10 Thyroid stimulating hormone; TGCT cis rs682748 0.967 rs297172 chr5:17150524 T/C cg23987134 chr5:17158319 LOC285696 -0.23 -5.42 -0.44 2.93e-7 Hippocampal atrophy; TGCT cis rs12540874 0.698 rs3807566 chr7:50564204 G/T cg18232548 chr7:50535776 DDC -0.36 -6.18 -0.49 8.57e-9 Systemic sclerosis; TGCT trans rs877282 0.898 rs12359731 chr10:759497 A/G cg22713356 chr15:30763199 NA 1.08 9.15 0.63 1.46e-15 Uric acid levels; TGCT cis rs769267 0.965 rs2315281 chr19:19480099 G/A cg03709012 chr19:19516395 GATAD2A -0.79 -6.75 -0.52 4.97e-10 Tonsillectomy; TGCT cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg11644478 chr21:40555479 PSMG1 1.01 10.47 0.69 8.99e-19 Cognitive function; TGCT cis rs9303401 0.659 rs62083362 chr17:56846464 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs7666738 0.927 rs4699328 chr4:99055890 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.53 0.44 1.85e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9527 0.590 rs7898770 chr10:104756636 A/G cg04362960 chr10:104952993 NT5C2 -0.69 -5.84 -0.46 4.23e-8 Arsenic metabolism; TGCT cis rs9814567 0.752 rs9848254 chr3:134330374 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3733585 0.699 rs7437120 chr4:9967683 T/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.67 -0.57 4.29e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg06238570 chr21:40685208 BRWD1 -0.83 -9.32 -0.64 5.46e-16 Cognitive function; TGCT cis rs2836974 0.966 rs7283420 chr21:40666865 T/C cg11890956 chr21:40555474 PSMG1 1.03 10.89 0.7 8.59e-20 Cognitive function; TGCT cis rs6430585 0.536 rs60397494 chr2:136470219 C/T cg07169764 chr2:136633963 MCM6 1.12 10.49 0.69 8.04e-19 Corneal structure; TGCT cis rs7804356 0.651 rs1123156 chr7:26817044 C/T cg03456212 chr7:26904342 SKAP2 -0.54 -4.54 -0.38 1.3e-5 Type 1 diabetes; TGCT cis rs6701037 0.748 rs2685 chr1:175127771 A/G cg00321850 chr1:175162397 KIAA0040 0.39 5.28 0.43 5.55e-7 Alcohol dependence; TGCT cis rs597539 0.652 rs546382 chr11:68704264 C/T cg21963583 chr11:68658836 MRPL21 0.37 6.08 0.48 1.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7737716 0.500 rs73790355 chr5:118235990 C/G cg21035905 chr5:118964330 FAM170A 0.41 4.69 0.39 7.18e-6 Cerebrospinal P-tau181p levels;Cerebrospinal T-tau levels; TGCT cis rs9926296 0.605 rs12599180 chr16:89839306 C/T cg21285383 chr16:89894308 SPIRE2 -0.44 -7.14 -0.54 7e-11 Vitiligo; TGCT cis rs5769765 0.955 rs8135963 chr22:50301476 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -10.56 -0.69 5.6e-19 Schizophrenia; TGCT cis rs6912958 0.712 rs2754260 chr6:88397666 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -4.46 -0.37 1.81e-5 Monocyte percentage of white cells; TGCT cis rs9921338 0.961 rs7193278 chr16:11445831 A/C cg00044050 chr16:11439710 C16orf75 -0.73 -5.69 -0.45 8.72e-8 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs40363 1.000 rs37769 chr16:3514580 C/G cg22508957 chr16:3507546 NAT15 0.57 5.15 0.42 1.01e-6 Tuberculosis; TGCT cis rs10751667 0.666 rs7396473 chr11:966181 T/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.66e-13 Alzheimer's disease (late onset); TGCT cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg17054783 chr10:134559939 INPP5A 0.23 4.64 0.38 8.89e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs459571 0.804 rs448918 chr9:136885979 G/A cg13789015 chr9:136890014 NCRNA00094 0.4 7.21 0.54 4.93e-11 Platelet distribution width; TGCT cis rs2456568 0.802 rs10831139 chr11:93640537 G/A cg14065697 chr11:93583672 C11orf90 -0.36 -4.45 -0.37 1.85e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7617773 0.743 rs13071960 chr3:48367537 A/G cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg20607798 chr8:58055168 NA 0.49 4.52 0.38 1.43e-5 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.724 rs2955371 chr17:17967397 G/A cg09796270 chr17:17721594 SREBF1 -0.28 -5.56 -0.45 1.6e-7 Total body bone mineral density; TGCT cis rs9634489 0.502 rs12431147 chr13:97112598 T/C cg11411106 chr13:97107445 HS6ST3 0.25 4.48 0.37 1.7e-5 Body mass index; TGCT cis rs9549367 0.789 rs9549715 chr13:113908240 G/C cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs10540 1.000 rs61742833 chr11:490035 C/T cg03934478 chr11:495069 RNH1 0.34 5.38 0.44 3.54e-7 Body mass index; TGCT cis rs981844 1.000 rs2606342 chr4:154659980 C/A cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs892961 0.932 rs3987886 chr17:75414980 A/G cg05865280 chr17:75406074 SEPT9 0.29 6.98 0.53 1.61e-10 Airflow obstruction; TGCT cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg11494091 chr17:61959527 GH2 -0.53 -11.85 -0.73 4e-22 Prudent dietary pattern; TGCT cis rs3733585 0.673 rs4447861 chr4:9953940 C/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2066819 1.000 rs75265219 chr12:56640341 G/A cg26714650 chr12:56694279 CS -1.32 -6.2 -0.49 7.69e-9 Psoriasis vulgaris; TGCT cis rs6901250 0.851 rs339324 chr6:117195024 C/T cg12892004 chr6:117198278 RFX6 -0.57 -6.94 -0.53 1.92e-10 C-reactive protein levels; TGCT cis rs447735 0.537 rs7190341 chr16:89917537 T/C cg03388025 chr16:89894329 SPIRE2 0.36 4.94 0.41 2.42e-6 Hemoglobin concentration; TGCT cis rs4455778 0.580 rs6976152 chr7:49087711 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs9467711 0.720 rs75782365 chr6:26408551 T/G cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs2251381 0.750 rs8129616 chr21:30520085 C/T cg24692254 chr21:30365293 RNF160 -0.69 -6.6 -0.51 1.08e-9 Selective IgA deficiency; TGCT trans rs2233152 0.519 rs11083567 chr19:41318306 C/T cg23963070 chr1:1162176 SDF4 0.32 6.74 0.52 5.22e-10 Kawasaki disease; TGCT cis rs9522267 0.535 rs9522303 chr13:112237301 T/C cg10483660 chr13:112241077 NA -0.28 -4.65 -0.39 8.46e-6 Hepatitis; TGCT cis rs2404602 0.716 rs17461634 chr15:76764107 G/A cg26408565 chr15:76604113 ETFA -0.39 -5.23 -0.43 6.85e-7 Blood metabolite levels; TGCT cis rs7178572 0.568 rs11630689 chr15:77520094 C/T cg22256960 chr15:77711686 NA -0.87 -8.8 -0.62 9.73e-15 Type 2 diabetes; TGCT cis rs9653442 0.564 rs10175599 chr2:100787635 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.46 -0.44 2.53e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1005277 0.579 rs2021649 chr10:38392122 C/T cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs7662987 0.517 rs1154410 chr4:100006645 A/G cg12011299 chr4:100065546 ADH4 0.38 4.6 0.38 1.04e-5 Smoking initiation; TGCT cis rs12142240 0.698 rs4372193 chr1:46853233 G/T cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs7681440 0.904 rs6816469 chr4:90772885 G/C cg14346243 chr4:90757452 SNCA -0.57 -5.5 -0.44 2.04e-7 Dementia with Lewy bodies; TGCT cis rs8180040 0.966 rs7649234 chr3:47494380 G/C cg27129171 chr3:47204927 SETD2 0.68 8.08 0.59 4.77e-13 Colorectal cancer; TGCT cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs3125734 0.633 rs3852412 chr10:64050288 C/T cg19640130 chr10:64028056 RTKN2 -0.38 -4.79 -0.39 4.73e-6 Rheumatoid arthritis; TGCT cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs10022389 chr4:99022229 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7726839 0.540 rs57306627 chr5:597643 T/C cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs2242116 1.000 rs1138518 chr3:46944274 T/C cg02527881 chr3:46936655 PTH1R -0.32 -6.08 -0.48 1.36e-8 Birth weight; TGCT cis rs1018836 0.892 rs10103198 chr8:91579436 A/T cg16814680 chr8:91681699 NA -0.77 -8.22 -0.59 2.28e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg06481639 chr22:41940642 POLR3H -0.68 -6.01 -0.48 1.89e-8 Vitiligo; TGCT cis rs7666738 0.546 rs62320963 chr4:98839297 A/G cg17366294 chr4:99064904 C4orf37 0.66 6.14 0.48 1.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7914558 1.000 rs1926030 chr10:104855656 T/C cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.66e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3784262 0.669 rs4646603 chr15:58290024 G/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.96 -0.47 2.49e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7843479 0.965 rs733544 chr8:21835628 A/G cg17168535 chr8:21777572 XPO7 0.63 5.8 0.46 5.08e-8 Mean corpuscular volume; TGCT cis rs9486719 1.000 rs12205728 chr6:96891838 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg00343986 chr7:65444356 GUSB -0.24 -5.81 -0.46 4.87e-8 Aortic root size; TGCT cis rs3806843 0.576 rs246028 chr5:140333513 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1903068 1.000 rs73236109 chr4:56007425 C/T cg16572876 chr4:56024045 NA 0.46 5.24 0.43 6.65e-7 Endometriosis; TGCT cis rs854765 0.583 rs11871899 chr17:17826748 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.94 0.58 1.04e-12 Total body bone mineral density; TGCT cis rs35146811 0.735 rs11764176 chr7:99786964 G/T cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs9985766 1.000 rs28896206 chr4:151034907 T/C cg05926478 chr4:151174724 DCLK2 -0.27 -4.81 -0.4 4.35e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg27588902 chr6:42928151 GNMT -0.56 -6.81 -0.52 3.8e-10 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs208520 0.754 rs851592 chr6:66875175 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.31 -0.68 2.29e-18 Exhaled nitric oxide output; TGCT cis rs477895 0.713 rs67546972 chr11:63962162 G/A cg23719950 chr11:63933701 MACROD1 -0.71 -5.87 -0.47 3.82e-8 Mean platelet volume; TGCT trans rs2898290 0.500 rs11998678 chr8:11830150 A/G cg15556689 chr8:8085844 FLJ10661 -0.73 -6.63 -0.51 9.2e-10 Systolic blood pressure; TGCT cis rs6901004 0.688 rs34151782 chr6:111574537 T/A cg15721981 chr6:111408429 SLC16A10 0.53 4.61 0.38 9.85e-6 Blood metabolite levels; TGCT cis rs7926906 0.679 rs7933305 chr11:90522199 A/T cg26138821 chr11:89956704 CHORDC1 -0.48 -4.94 -0.41 2.49e-6 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs116559327 chr4:119754526 T/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2180341 0.842 rs9372860 chr6:127546605 G/A cg27446573 chr6:127587934 RNF146 1.07 8.4 0.6 8.9e-14 Breast cancer; TGCT trans rs208520 0.874 rs208518 chr6:66948501 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.95 9.89 0.66 2.33e-17 Exhaled nitric oxide output; TGCT cis rs4788570 0.566 rs8051439 chr16:71495793 A/T cg06353428 chr16:71660113 MARVELD3 -1.2 -7.67 -0.57 4.25e-12 Intelligence (multi-trait analysis); TGCT cis rs42648 0.748 rs12673914 chr7:89943389 C/T cg25739043 chr7:89950458 NA -0.63 -6.12 -0.48 1.12e-8 Homocysteine levels; TGCT cis rs7666738 0.830 rs6831219 chr4:98993576 C/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7599312 0.534 rs6435711 chr2:213410065 G/A cg20637307 chr2:213403960 ERBB4 0.89 10.96 0.7 5.75e-20 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs644799 1.000 rs3177463 chr11:95502128 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.53 0.61 4.41e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9486715 0.867 rs4839828 chr6:96863326 G/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs5750830 0.649 rs4337572 chr22:39800704 C/G cg01416388 chr22:39784598 NA -0.63 -5.27 -0.43 5.87e-7 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.566 rs9358902 chr6:26058570 C/G cg16482183 chr6:26056742 HIST1H1C 0.58 4.98 0.41 2.12e-6 Height; TGCT trans rs1005277 0.540 rs2474598 chr10:38430296 C/T cg27523141 chr10:43048294 ZNF37B -0.73 -8.38 -0.6 9.87e-14 Extrinsic epigenetic age acceleration; TGCT cis rs6746896 1.000 rs56361249 chr2:97380229 T/G cg26085987 chr2:97230376 NA 0.19 4.66 0.39 8.15e-6 Bipolar disorder; TGCT cis rs854765 0.964 rs72827413 chr17:17988299 C/T cg09796270 chr17:17721594 SREBF1 -0.26 -5.02 -0.41 1.73e-6 Total body bone mineral density; TGCT cis rs6752107 1.000 rs13009506 chr2:234175706 A/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 -0.19 -4.65 -0.39 8.35e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs854765 0.693 rs9907287 chr17:17774118 C/T cg09796270 chr17:17721594 SREBF1 -0.24 -4.8 -0.4 4.56e-6 Total body bone mineral density; TGCT cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg21280719 chr6:42927975 GNMT -0.37 -4.59 -0.38 1.07e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2224391 0.628 rs2753238 chr6:5252795 A/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.99 -6.43 -0.5 2.46e-9 Height; TGCT cis rs4788570 0.566 rs3886947 chr16:71483958 G/C cg06353428 chr16:71660113 MARVELD3 -1.32 -7.86 -0.58 1.6e-12 Intelligence (multi-trait analysis); TGCT cis rs12643440 0.538 rs62296722 chr4:17140970 T/G cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs4665809 0.816 rs2384359 chr2:26371364 T/C cg22920501 chr2:26401640 FAM59B -0.72 -6.19 -0.49 8.23e-9 Gut microbiome composition (summer); TGCT cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg11890956 chr21:40555474 PSMG1 -1.1 -12.05 -0.73 1.27e-22 Cognitive function; TGCT cis rs308403 0.568 rs13102440 chr4:123664919 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.7 6.51 0.5 1.66e-9 Blood protein levels; TGCT cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6674970 1.000 rs4970941 chr1:151068546 A/G cg00003202 chr1:151319512 RFX5 -0.51 -4.46 -0.37 1.84e-5 Childhood ear infection; TGCT cis rs3091242 0.836 rs35346083 chr1:25788425 C/A cg10117171 chr1:25599238 RHD 0.32 5.16 0.42 9.43e-7 Erythrocyte sedimentation rate; TGCT cis rs1372520 0.577 rs748849 chr4:90734961 G/A cg14346243 chr4:90757452 SNCA -0.66 -5.56 -0.45 1.55e-7 Neuroticism; TGCT cis rs769267 0.895 rs2965182 chr19:19548246 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.25 0.43 6.3e-7 Tonsillectomy; TGCT cis rs7000551 0.751 rs2461490 chr8:22370115 G/C cg12081754 chr8:22256438 SLC39A14 0.27 4.51 0.38 1.48e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6459788 0.502 rs9692347 chr7:157232659 C/T cg03453431 chr7:157225567 NA -0.54 -8.9 -0.62 5.77e-15 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7760949 0.889 rs9475787 chr6:13926102 G/C cg27413430 chr6:13925136 RNF182 0.74 6.82 0.52 3.64e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs524281 0.861 rs580891 chr11:65954681 A/C cg00563793 chr11:65837595 PACS1 0.56 4.88 0.4 3.22e-6 Electroencephalogram traits; TGCT cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg08645402 chr16:4508243 NA 0.2 4.78 0.39 4.87e-6 Schizophrenia; TGCT cis rs7246657 0.943 rs10417844 chr19:37837587 C/T cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.3e-7 Coronary artery calcification; TGCT cis rs9905704 0.647 rs11659035 chr17:56966052 C/T cg05425664 chr17:57184151 TRIM37 -0.57 -4.44 -0.37 1.97e-5 Testicular germ cell tumor; TGCT cis rs12510870 0.599 rs2103323 chr4:74422785 A/T cg05868023 chr4:75230803 EREG 0.62 5.03 0.41 1.68e-6 Iris color (b* coordinate); TGCT cis rs6964587 0.900 rs6972027 chr7:91781380 T/C cg17063962 chr7:91808500 NA 0.93 10.08 0.67 8.03e-18 Breast cancer; TGCT cis rs4711350 0.765 rs943476 chr6:33750086 A/G cg00334056 chr6:33755658 LEMD2 -0.28 -4.47 -0.37 1.73e-5 Schizophrenia; TGCT cis rs33794 0.901 rs33786 chr3:45293379 C/T cg18645101 chr3:44551900 NA 0.54 4.74 0.39 5.75e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs73198271 1.000 rs73198271 chr8:8606807 A/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs3733585 0.736 rs4543113 chr4:10008305 G/A cg11266682 chr4:10021025 SLC2A9 0.64 8.27 0.6 1.75e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9677476 0.516 rs1035620 chr2:232008305 C/T cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs76935404 0.811 rs11083589 chr19:41428416 A/T cg19493303 chr19:41414353 NA 0.41 5.05 0.41 1.57e-6 nicotine metabolite ratio in current smokers; TGCT cis rs9902453 0.730 rs2020939 chr17:28550732 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.58 -5.41 -0.44 3.14e-7 Coffee consumption (cups per day); TGCT cis rs2594989 0.831 rs66488222 chr3:11576289 C/T cg00170343 chr3:11313890 ATG7 -0.65 -4.92 -0.4 2.71e-6 Circulating chemerin levels; TGCT cis rs67311347 0.956 rs11714871 chr3:40428938 T/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.29e-6 Renal cell carcinoma; TGCT cis rs1348850 0.837 rs4243388 chr2:178284604 T/G cg22681709 chr2:178499509 PDE11A -0.35 -4.6 -0.38 1.03e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1577917 1.000 rs1999852 chr6:86705738 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs3617 0.625 rs2071042 chr3:52864584 A/G cg10802521 chr3:52805072 NEK4 -0.62 -7.17 -0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9902453 0.808 rs8069669 chr17:28239502 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.88 8.32 0.6 1.33e-13 Coffee consumption (cups per day); TGCT cis rs2832077 0.527 rs2832116 chr21:30228368 C/A cg24692254 chr21:30365293 RNF160 -0.59 -5.05 -0.41 1.53e-6 Cognitive test performance; TGCT cis rs4253772 0.550 rs9615913 chr22:46668515 A/T cg24881330 chr22:46731750 TRMU -0.67 -4.49 -0.37 1.6e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs2296887 0.722 rs10883715 chr10:103960817 C/T cg26089160 chr10:104170217 PSD -0.53 -4.82 -0.4 4.08e-6 Parkinson's disease; TGCT cis rs60871478 0.898 rs4720929 chr7:808009 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.6 0.38 1.04e-5 Cerebrospinal P-tau181p levels; TGCT cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg07507251 chr3:52567010 NT5DC2 0.48 6.76 0.52 4.9e-10 Bipolar disorder; TGCT cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.65 -6.31 -0.49 4.42e-9 Bipolar disorder; TGCT cis rs6840360 0.593 rs10016160 chr4:152693998 A/G cg17479576 chr4:152424074 FAM160A1 -0.53 -5.26 -0.43 5.99e-7 Intelligence (multi-trait analysis); TGCT cis rs3087591 0.919 rs2940180 chr17:29409347 G/T cg24425628 chr17:29625626 OMG;NF1 0.46 6.91 0.53 2.23e-10 Hip circumference; TGCT cis rs7568458 0.837 rs35565292 chr2:85790316 T/A cg17127132 chr2:85788382 GGCX 0.72 6.86 0.52 2.87e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2836974 0.799 rs8129303 chr21:40711959 G/A cg17971929 chr21:40555470 PSMG1 0.89 7.75 0.57 2.88e-12 Cognitive function; TGCT cis rs7192750 0.586 rs8063324 chr16:71967599 T/G cg06353428 chr16:71660113 MARVELD3 0.76 6.91 0.53 2.2e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs981844 0.712 rs1037648 chr4:154737877 T/C cg14289246 chr4:154710475 SFRP2 -1.0 -9.32 -0.64 5.46e-16 Response to statins (LDL cholesterol change); TGCT cis rs9818758 0.556 rs11716614 chr3:49017208 C/G cg00383909 chr3:49044727 WDR6 1.54 5.91 0.47 3.14e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4953076 0.573 rs2053456 chr2:44448632 G/A cg04920474 chr2:44395004 PPM1B 0.6 6.06 0.48 1.51e-8 Height; TGCT cis rs2836974 0.897 rs2836923 chr21:40524236 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.08 0.63 2.09e-15 Cognitive function; TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.69 -0.39 7.05e-6 Prudent dietary pattern; TGCT cis rs12142240 0.698 rs6659228 chr1:46811027 C/G cg00530320 chr1:46809349 NSUN4 0.29 5.83 0.46 4.47e-8 Menopause (age at onset); TGCT cis rs514406 0.584 rs11205997 chr1:53195271 G/C cg16325326 chr1:53192061 ZYG11B -0.89 -13.12 -0.76 3.31e-25 Monocyte count; TGCT cis rs854765 0.718 rs7224815 chr17:17845800 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.65 6.41 0.5 2.72e-9 Total body bone mineral density; TGCT cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg21724239 chr8:58056113 NA 0.52 5.53 0.44 1.8e-7 Developmental language disorder (linguistic errors); TGCT cis rs6752107 1.000 rs3828309 chr2:234180410 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 -0.2 -4.82 -0.4 4.11e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs929354 0.742 rs10274687 chr7:156933181 T/G cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs56235845 0.964 rs11746443 chr5:176798306 G/A cg16006841 chr5:176797999 RGS14 0.75 12.79 0.75 2.1e-24 Hemoglobin concentration;Hematocrit; TGCT cis rs2216164 1.000 rs2069718 chr12:68550162 A/G cg17065850 chr12:67807625 NA 0.24 4.48 0.37 1.64e-5 Alopecia areata; TGCT cis rs17384381 0.953 rs3768223 chr1:85809183 T/C cg16011679 chr1:85725395 C1orf52 0.84 6.5 0.5 1.74e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2066819 1.000 rs11171806 chr12:56733531 A/G cg26714650 chr12:56694279 CS 1.35 5.71 0.46 7.97e-8 Psoriasis vulgaris; TGCT cis rs4788570 0.615 rs7190487 chr16:71648617 A/G cg06353428 chr16:71660113 MARVELD3 1.54 12.75 0.75 2.57e-24 Intelligence (multi-trait analysis); TGCT cis rs1005277 0.540 rs7903942 chr10:37929276 C/T cg25427524 chr10:38739819 LOC399744 0.36 7.13 0.54 7.4e-11 Extrinsic epigenetic age acceleration; TGCT cis rs826838 0.834 rs2387842 chr12:38736442 T/C cg26384229 chr12:38710491 ALG10B 1.09 10.99 0.7 4.95e-20 Heart rate; TGCT cis rs6582630 0.502 rs11520234 chr12:38255005 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs6728642 1.000 rs7580504 chr2:97605597 C/G cg26665480 chr2:98280029 ACTR1B -0.95 -5.35 -0.43 4.15e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs78487399 0.808 rs17030925 chr2:43713808 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -4.68 -0.39 7.4e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9910055 0.659 rs8079310 chr17:42270291 A/G cg13607699 chr17:42295918 UBTF 0.56 5.15 0.42 1.01e-6 Total body bone mineral density; TGCT cis rs9486715 0.867 rs7451950 chr6:96879974 T/C cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs11623869 0.772 rs12587310 chr14:103907286 G/A cg26031613 chr14:104095156 KLC1 -0.87 -9.58 -0.65 1.3e-16 Bone mineral density; TGCT trans rs7613875 0.600 rs2624832 chr3:50030858 C/T cg21659725 chr3:3221576 CRBN 0.67 7.53 0.56 9.05e-12 Body mass index; TGCT cis rs2997447 0.739 rs60141220 chr1:26395741 G/A cg19633962 chr1:26362018 EXTL1 -0.68 -4.7 -0.39 6.68e-6 QRS complex (12-leadsum); TGCT cis rs3008870 0.755 rs2815374 chr1:67507387 G/A cg02640540 chr1:67518911 SLC35D1 0.51 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs7267979 1.000 rs6050630 chr20:25430745 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1008375 1.000 rs7673500 chr4:17621383 C/T cg16339924 chr4:17578868 LAP3 0.65 5.21 0.42 7.61e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg03517284 chr6:25882590 NA -0.71 -6.48 -0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.52 5.54 0.45 1.73e-7 Lymphocyte counts; TGCT cis rs3617 0.573 rs6795646 chr3:52922621 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.53 5.22 0.42 7.26e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1218582 0.741 rs10908446 chr1:154869559 G/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.13 -0.54 7.13e-11 Prostate cancer; TGCT cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.14e-6 Blood metabolite levels; TGCT cis rs7860634 1.000 rs7860634 chr9:139089679 C/T cg04455058 chr9:139085579 NA 0.49 5.45 0.44 2.56e-7 Thyroid hormone levels; TGCT cis rs3809566 0.963 rs3809565 chr15:63333619 A/G cg08198488 chr15:63333792 TPM1 -0.35 -5.15 -0.42 1e-6 Platelet count; TGCT cis rs28595532 0.920 rs115485705 chr4:119733286 G/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs6740322 0.793 rs9808360 chr2:43546835 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -7.0 -0.53 1.42e-10 Coronary artery disease; TGCT cis rs858239 0.669 rs1990365 chr7:23115966 T/C cg05602783 chr7:23145260 KLHL7 -0.54 -4.54 -0.38 1.33e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs151997 0.830 rs27282 chr5:50198970 G/A cg06027927 chr5:50259733 NA 0.54 5.58 0.45 1.46e-7 Callous-unemotional behaviour; TGCT cis rs2836950 0.772 rs62222988 chr21:40569508 T/C cg06238570 chr21:40685208 BRWD1 -0.56 -5.63 -0.45 1.12e-7 Menarche (age at onset); TGCT cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs1799949 0.773 rs2137990 chr17:41317896 T/A cg23758822 chr17:41437982 NA -0.67 -6.57 -0.51 1.23e-9 Menopause (age at onset); TGCT cis rs3749237 0.576 rs3877784 chr3:49539417 C/T cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs7267979 0.966 rs2387882 chr20:25378802 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9929218 0.551 rs2274239 chr16:68725783 G/A cg01251360 chr16:68772225 CDH1 -0.29 -5.42 -0.44 2.97e-7 Colorectal cancer; TGCT cis rs7246657 0.943 rs7255996 chr19:37971699 G/A cg18154014 chr19:37997991 ZNF793 0.74 5.44 0.44 2.71e-7 Coronary artery calcification; TGCT cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg03609598 chr5:56110824 MAP3K1 -0.56 -4.57 -0.38 1.14e-5 Initial pursuit acceleration; TGCT cis rs739496 0.947 rs11608565 chr12:111921926 T/A cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.1e-7 Platelet count; TGCT cis rs1577917 1.000 rs10944161 chr6:86630376 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs669446 0.561 rs664728 chr1:44101714 A/T cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs10509586 1.000 rs76543761 chr10:91808407 T/C cg25278353 chr10:91717815 NA 0.48 4.53 0.38 1.35e-5 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg13607699 chr17:42295918 UBTF 0.59 5.31 0.43 4.88e-7 Total body bone mineral density; TGCT cis rs7647973 0.626 rs1352889 chr3:49652148 T/C cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs875971 0.964 rs9691480 chr7:65944306 A/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs588177 0.522 rs34358026 chr11:64015422 T/C cg23719950 chr11:63933701 MACROD1 -0.68 -5.65 -0.45 1.03e-7 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2439831 0.850 rs28513374 chr15:44125495 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT cis rs514406 0.861 rs503296 chr1:53283088 A/G cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs7829975 0.582 rs11783950 chr8:8597831 A/C cg17143192 chr8:8559678 CLDN23 -0.51 -5.11 -0.42 1.21e-6 Mood instability; TGCT cis rs875971 0.862 rs908915 chr7:65614651 G/T cg11764359 chr7:65958608 NA -0.56 -5.09 -0.42 1.31e-6 Aortic root size; TGCT cis rs60871478 0.579 rs56109762 chr7:925967 G/A cg00475322 chr7:917719 C7orf20 0.56 5.37 0.43 3.72e-7 Cerebrospinal P-tau181p levels; TGCT cis rs7681423 1.000 rs2066861 chr4:155527436 C/T cg20735720 chr4:155535218 FGG -0.46 -6.8 -0.52 4e-10 Fibrinogen; TGCT cis rs7940866 0.740 rs7131121 chr11:130806424 A/G cg12179176 chr11:130786555 SNX19 0.59 5.89 0.47 3.41e-8 Schizophrenia; TGCT cis rs597539 0.652 rs686390 chr11:68656077 T/C cg21963583 chr11:68658836 MRPL21 0.37 6.18 0.48 8.66e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs4650994 0.789 rs2476559 chr1:178592919 A/G cg05059571 chr16:84539110 KIAA1609 0.41 7.51 0.56 1e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6831352 0.879 rs29001208 chr4:100052539 A/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs6867032 1.000 rs16902318 chr5:2013568 A/G cg26168224 chr5:2018326 NA 0.46 8.36 0.6 1.08e-13 Gut microbiome composition (winter); TGCT cis rs9660992 0.710 rs1668872 chr1:205236069 G/A cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs9611565 0.559 rs7290990 chr22:41964357 C/A cg13695892 chr22:41940480 POLR3H -0.87 -8.17 -0.59 2.95e-13 Vitiligo; TGCT cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.82 0.4 4.1e-6 Lung function (FEV1/FVC); TGCT cis rs2010099 0.775 rs73191624 chr3:124308208 C/T cg17170942 chr3:124452405 UMPS -0.38 -4.51 -0.38 1.47e-5 Thyroid peroxidase antibody levels; TGCT cis rs7726839 0.540 rs11738281 chr5:662547 T/C cg16035780 chr5:759353 NA 0.44 4.49 0.37 1.63e-5 Obesity-related traits; TGCT cis rs698813 0.604 rs2340813 chr2:44487398 T/C cg00619915 chr2:44497795 NA -0.25 -5.7 -0.46 8.4e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs1799949 0.930 rs34210004 chr17:41370337 A/T cg23758822 chr17:41437982 NA 0.62 6.16 0.48 9.19e-9 Menopause (age at onset); TGCT cis rs910187 0.605 rs8184673 chr20:45806262 C/T cg27589058 chr20:45804311 EYA2 -0.38 -8.4 -0.6 8.83e-14 Migraine; TGCT cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg22963979 chr7:1858916 MAD1L1 -0.41 -6.4 -0.5 2.92e-9 Bipolar disorder and schizophrenia; TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs5769765 0.542 rs1033666 chr22:50252783 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.97 6.35 0.5 3.69e-9 Schizophrenia; TGCT cis rs2637266 1.000 rs2637264 chr10:78322794 A/C cg18941641 chr10:78392320 NA 0.39 4.84 0.4 3.73e-6 Pulmonary function; TGCT cis rs4746818 1.000 rs6480383 chr10:70890482 C/T cg11621586 chr10:70884670 VPS26A 1.21 10.66 0.69 3.17e-19 Left atrial antero-posterior diameter; TGCT cis rs35306767 0.903 rs11816064 chr10:931176 A/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs4975616 0.869 rs466502 chr5:1325767 C/T cg07493874 chr5:1342172 CLPTM1L 0.29 6.87 0.53 2.72e-10 Lung cancer; TGCT cis rs3849570 0.925 rs9841087 chr3:81907949 A/G cg07356753 chr3:81810745 GBE1 -0.72 -6.62 -0.51 9.51e-10 Waist circumference;Body mass index; TGCT cis rs13082711 0.555 rs7627508 chr3:27252495 A/C cg02860705 chr3:27208620 NA 0.46 7.16 0.54 6.15e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs12188164 1.000 rs72717410 chr5:428785 A/T cg26850624 chr5:429559 AHRR -0.2 -4.82 -0.4 4.15e-6 Cystic fibrosis severity; TGCT cis rs7677751 0.806 rs67432867 chr4:55104454 A/T cg17187183 chr4:55093834 PDGFRA 0.54 7.0 0.53 1.45e-10 Corneal astigmatism; TGCT cis rs9527 0.590 rs7917650 chr10:104937100 G/C cg04362960 chr10:104952993 NT5C2 0.65 5.59 0.45 1.36e-7 Arsenic metabolism; TGCT cis rs4389656 0.775 rs274668 chr5:6711630 C/T cg10857441 chr5:6722123 POLS -0.22 -4.87 -0.4 3.27e-6 Coronary artery disease; TGCT cis rs9818758 0.556 rs9813813 chr3:49207093 T/A cg07636037 chr3:49044803 WDR6 -1.03 -5.08 -0.41 1.37e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1245541 0.776 rs1678613 chr10:73866511 T/C cg10983208 chr10:73848320 SPOCK2 -0.27 -4.57 -0.38 1.14e-5 Insulin-like growth factors; TGCT cis rs9372498 0.505 rs17080456 chr6:118985938 G/C cg07617317 chr6:118971624 C6orf204 0.49 5.15 0.42 9.91e-7 Diastolic blood pressure; TGCT cis rs8020441 0.945 rs67713610 chr14:51168830 C/T cg04730355 chr14:51134070 SAV1 0.73 6.02 0.48 1.84e-8 Cognitive performance; TGCT cis rs7731657 0.509 rs916956 chr5:130331705 C/G cg08523029 chr5:130500466 HINT1 -0.59 -4.84 -0.4 3.76e-6 Fasting plasma glucose; TGCT cis rs7267979 0.966 rs2257712 chr20:25264910 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3617 0.573 rs9880978 chr3:52923251 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.95 0.41 2.4e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.791 rs34088022 chr4:99001508 G/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.764 rs9322028 chr6:145895797 G/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6831352 0.734 rs2602856 chr4:100029145 C/A cg12011299 chr4:100065546 ADH4 0.41 5.67 0.45 9.34e-8 Alcohol dependence; TGCT cis rs11677416 1.000 rs3783559 chr2:113529837 A/G cg27083787 chr2:113543245 IL1A 0.18 4.5 0.37 1.53e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs4803468 1.000 rs2288871 chr19:41917868 C/T cg09537434 chr19:41945824 ATP5SL -0.9 -10.87 -0.7 9.43e-20 Height; TGCT cis rs9357506 1.000 rs12055793 chr6:46306389 T/A cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs56309584 0.560 rs3027169 chr17:8058814 A/C cg08322244 chr17:8066669 VAMP2 -0.52 -4.88 -0.4 3.14e-6 Initial pursuit acceleration; TGCT cis rs9362426 0.608 rs6912875 chr6:88133503 A/T cg10919329 chr6:88182879 SLC35A1 -0.61 -4.61 -0.38 9.99e-6 Depressive episodes in bipolar disorder; TGCT cis rs7949030 0.688 rs11231155 chr11:62365619 A/G cg11742103 chr11:62369870 EML3;MTA2 0.62 9.04 0.63 2.68e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.548 rs6670871 chr1:53212082 A/C cg16325326 chr1:53192061 ZYG11B -0.9 -13.21 -0.76 2.07e-25 Monocyte count; TGCT cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg18230493 chr5:56204884 C5orf35 -0.72 -6.07 -0.48 1.44e-8 Initial pursuit acceleration; TGCT cis rs28595532 0.920 rs17324968 chr4:119772316 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs13064411 0.696 rs1386336 chr3:113144153 C/T cg18753928 chr3:113234510 CCDC52 -0.71 -4.98 -0.41 2.06e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs778371 0.752 rs283487 chr2:233644011 A/G cg08000102 chr2:233561755 GIGYF2 0.69 7.78 0.57 2.37e-12 Schizophrenia; TGCT cis rs6952808 0.717 rs12534679 chr7:1926745 G/A cg22963979 chr7:1858916 MAD1L1 -0.37 -5.67 -0.45 9.59e-8 Bipolar disorder and schizophrenia; TGCT cis rs10992471 0.528 rs10761158 chr9:95205322 T/G cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7224685 0.569 rs8065660 chr17:4000858 A/G cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs3772130 0.527 rs2141614 chr3:121590173 G/A cg20356878 chr3:121714668 ILDR1 0.38 4.83 0.4 3.93e-6 Cognitive performance; TGCT cis rs7106204 0.748 rs2403888 chr11:24208071 C/G ch.11.24196551F chr11:24239977 NA -0.5 -4.64 -0.38 8.82e-6 Response to Homoharringtonine (cytotoxicity); TGCT cis rs6430585 0.527 rs2278731 chr2:136396300 T/C cg07169764 chr2:136633963 MCM6 0.98 8.33 0.6 1.3e-13 Corneal structure; TGCT cis rs4689388 0.926 rs28420833 chr4:6279504 G/A cg25554036 chr4:6271136 WFS1 0.55 8.09 0.59 4.65e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs736408 0.812 rs2240920 chr3:52831009 A/G cg10802521 chr3:52805072 NEK4 0.65 7.13 0.54 7.35e-11 Bipolar disorder; TGCT cis rs7666738 0.753 rs10029372 chr4:98859002 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs270601 0.866 rs460271 chr5:131630062 C/G cg24060327 chr5:131705240 SLC22A5 -0.71 -7.2 -0.54 5.07e-11 Acylcarnitine levels; TGCT cis rs7119 0.635 rs2682910 chr15:77880114 C/A cg27398640 chr15:77910606 LINGO1 0.31 6.19 0.49 8.26e-9 Type 2 diabetes; TGCT cis rs2066819 1.000 rs77032009 chr12:56679971 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs7666738 0.830 rs17548431 chr4:98923768 C/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9296661 0.868 rs1326577 chr6:51667838 A/G cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs77972916 0.536 rs11694173 chr2:43590899 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.34 4.89 0.4 3.01e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg08048268 chr3:133502702 NA -0.7 -11.01 -0.7 4.4e-20 Iron status biomarkers; TGCT cis rs1865760 0.551 rs9461230 chr6:26019240 G/C cg16482183 chr6:26056742 HIST1H1C 0.59 5.16 0.42 9.65e-7 Height; TGCT cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg02953382 chr22:24373134 LOC391322 0.77 7.96 0.58 9.07e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg12311346 chr5:56204834 C5orf35 0.67 6.82 0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs35934224 0.783 rs7289343 chr22:19860990 G/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.04e-7 Glaucoma (primary open-angle); TGCT cis rs2562456 0.917 rs9304987 chr19:21682274 A/T cg25650185 chr19:21324782 ZNF431 0.59 5.18 0.42 8.79e-7 Pain; TGCT cis rs7681440 0.904 rs3806789 chr4:90759556 C/T cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.87e-8 Dementia with Lewy bodies; TGCT cis rs801193 1.000 rs7782320 chr7:66177098 C/T cg00343986 chr7:65444356 GUSB 0.22 5.0 0.41 1.9e-6 Aortic root size; TGCT cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg20607798 chr8:58055168 NA 0.45 4.62 0.38 9.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs8016982 0.630 rs61980900 chr14:81686436 T/C cg01989461 chr14:81687754 GTF2A1 0.81 8.55 0.61 3.82e-14 Schizophrenia; TGCT cis rs79349575 0.777 rs28517720 chr17:46976756 C/G cg07967210 chr17:47022446 SNF8 0.43 6.08 0.48 1.4e-8 Type 2 diabetes; TGCT cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg16145915 chr7:1198662 ZFAND2A -0.54 -6.95 -0.53 1.86e-10 Longevity;Endometriosis; TGCT cis rs9291683 0.632 rs12508991 chr4:10041104 C/T cg00071950 chr4:10020882 SLC2A9 0.68 8.73 0.62 1.45e-14 Bone mineral density; TGCT cis rs11997175 0.574 rs12156280 chr8:33650277 C/T ch.8.33884649F chr8:33765107 NA 0.28 4.53 0.38 1.35e-5 Body mass index; TGCT cis rs10197940 0.662 rs6735771 chr2:152273503 G/A cg06191203 chr2:152266755 RIF1 0.71 6.28 0.49 5.14e-9 Lung cancer; TGCT cis rs7119 0.651 rs12904823 chr15:77837662 G/A cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.16e-6 Type 2 diabetes; TGCT cis rs1670533 1.000 rs604597 chr4:1094151 G/A cg20887711 chr4:1340912 KIAA1530 -0.7 -5.53 -0.45 1.77e-7 Recombination rate (females); TGCT cis rs13191362 0.810 rs66921603 chr6:162996982 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs13040088 0.580 rs11905041 chr20:61563408 C/T cg23096297 chr20:61557774 DIDO1 0.8 6.41 0.5 2.81e-9 Menopause (age at onset); TGCT trans rs2727020 0.656 rs7925524 chr11:49437542 G/A cg03929089 chr4:120376271 NA -0.68 -7.15 -0.54 6.64e-11 Coronary artery disease; TGCT cis rs9910055 0.683 rs7220138 chr17:42254011 C/G cg19774624 chr17:42201019 HDAC5 -0.85 -10.09 -0.67 7.79e-18 Total body bone mineral density; TGCT cis rs1784581 0.532 rs7767219 chr6:162423088 T/C cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs8017423 0.669 rs7153190 chr14:90703904 T/G cg04374321 chr14:90722782 PSMC1 0.78 8.1 0.59 4.38e-13 Mortality in heart failure; TGCT cis rs5750830 0.594 rs1010170 chr22:39778327 C/T cg01416388 chr22:39784598 NA 0.64 6.16 0.48 9.43e-9 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.932 rs6449321 chr4:17644472 A/G cg10189774 chr4:17578691 LAP3 0.58 4.99 0.41 1.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs208520 0.690 rs12201219 chr6:66748862 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs2456568 0.900 rs877340 chr11:93689292 A/T cg17595323 chr11:93583763 C11orf90 -0.47 -6.05 -0.48 1.55e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs933688 1.000 rs933688 chr5:90762748 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 9.34 0.64 4.9e-16 Smoking behavior; TGCT cis rs4771122 0.740 rs1006353 chr13:28047269 A/G cg22138327 chr13:27999177 GTF3A -0.78 -7.46 -0.56 1.32e-11 Body mass index; TGCT cis rs6964587 0.626 rs409 chr7:91556355 C/T cg17063962 chr7:91808500 NA 0.76 7.24 0.55 4.11e-11 Breast cancer; TGCT cis rs6969780 0.722 rs4722666 chr7:27197601 C/G cg11410718 chr7:27170412 HOXA4 -0.46 -4.57 -0.38 1.18e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs210138 0.832 rs375555 chr6:33557741 T/C cg07679836 chr6:33548423 BAK1 0.35 4.62 0.38 9.34e-6 Testicular germ cell tumor; TGCT cis rs11997175 0.574 rs4733453 chr8:33650745 A/G ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT trans rs3780486 0.541 rs10738909 chr9:33148834 T/C cg04842962 chr6:43655489 MRPS18A 0.8 8.61 0.61 2.79e-14 IgG glycosylation; TGCT cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg02891314 chr5:179741120 GFPT2 -0.41 -7.12 -0.54 7.59e-11 Height; TGCT trans rs10802346 0.545 rs10924568 chr1:246385482 C/A cg22732515 chr19:44031385 ETHE1 0.83 6.62 0.51 9.79e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs1997103 1.000 rs2331063 chr7:55408914 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4455778 0.561 rs6952745 chr7:49122762 C/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs1670533 1.000 rs6852155 chr4:1067638 T/G cg20887711 chr4:1340912 KIAA1530 0.65 5.19 0.42 8.29e-7 Recombination rate (females); TGCT cis rs453301 0.653 rs1562211 chr8:8902424 A/G cg08975724 chr8:8085496 FLJ10661 -0.59 -5.13 -0.42 1.09e-6 Joint mobility (Beighton score); TGCT cis rs12908161 1.000 rs12910012 chr15:85298662 T/C cg17173187 chr15:85201210 NMB 0.57 6.41 0.5 2.81e-9 Schizophrenia; TGCT cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg07092213 chr7:1199455 ZFAND2A -0.45 -4.85 -0.4 3.58e-6 Longevity;Endometriosis; TGCT cis rs1532993 0.518 rs1508462 chr4:98582307 G/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.8 -0.4 4.45e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6426558 0.537 rs10799381 chr1:227239746 G/T cg10327440 chr1:227177885 CDC42BPA 0.61 7.41 0.55 1.72e-11 Neutrophil percentage of white cells; TGCT cis rs28595532 0.920 rs114696063 chr4:119760624 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs4273100 0.541 rs973649 chr17:19292068 A/G cg03910582 chr17:19030146 GRAPL -0.45 -6.22 -0.49 6.97e-9 Schizophrenia; TGCT cis rs67366981 0.720 rs4447349 chr14:77685381 G/A cg22824376 chr14:77648248 TMEM63C 0.74 4.75 0.39 5.58e-6 Obsessive-compulsive symptoms; TGCT cis rs4727027 0.833 rs2107846 chr7:148832774 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7547997 0.615 rs12038925 chr1:158319449 G/A cg07950803 chr1:158223934 CD1A 0.31 4.71 0.39 6.42e-6 QRS duration; TGCT cis rs611744 0.934 rs672408 chr8:109224390 A/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg09436375 chr6:42928200 GNMT -0.4 -5.2 -0.42 8.08e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12464483 0.524 rs1348898 chr2:30888026 C/A cg12454169 chr2:30669597 LCLAT1 0.45 4.91 0.4 2.75e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs155076 1.000 rs155076 chr13:21870114 A/G cg14456004 chr13:21872349 NA -1.18 -10.19 -0.68 4.35e-18 White matter hyperintensity burden; TGCT cis rs4713118 0.629 rs203889 chr6:28021775 T/G cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs7681440 0.804 rs763443 chr4:90819961 T/C cg20003494 chr4:90757398 SNCA -0.54 -5.1 -0.42 1.22e-6 Dementia with Lewy bodies; TGCT cis rs11112613 0.609 rs11112585 chr12:105933442 A/G cg03607813 chr12:105948248 NA -0.44 -4.96 -0.41 2.32e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs4455778 0.596 rs7777887 chr7:49020978 C/T cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs12510870 0.634 rs4694173 chr4:74382790 T/A cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs2235642 0.928 rs9932984 chr16:1605051 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.26 -0.43 6.24e-7 Coronary artery disease; TGCT cis rs7394190 0.748 rs11000780 chr10:75559077 G/A cg07699608 chr10:75541558 CHCHD1 0.79 5.45 0.44 2.63e-7 Incident atrial fibrillation; TGCT cis rs2228479 0.867 rs12919804 chr16:89945369 G/A cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs9788682 1.000 rs2036534 chr15:78826948 T/C cg24631222 chr15:78858424 CHRNA5 0.92 7.54 0.56 8.79e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs131805 1.000 rs131805 chr22:50964153 T/C cg25309564 chr22:51001381 C22orf41 0.57 4.77 0.39 5.06e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs422249 0.819 rs174608 chr11:61627484 A/G cg01500311 chr11:61656094 FADS3 -0.32 -5.3 -0.43 5.2e-7 Trans fatty acid levels; TGCT cis rs9325144 0.560 rs11182979 chr12:38642562 C/A cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 1.97e-8 Morning vs. evening chronotype; TGCT cis rs709400 0.663 rs11624367 chr14:103892818 T/A cg26031613 chr14:104095156 KLC1 0.88 9.61 0.65 1.09e-16 Body mass index; TGCT cis rs12188164 1.000 rs72717410 chr5:428785 A/T cg21144161 chr5:423903 AHRR 0.25 4.75 0.39 5.57e-6 Cystic fibrosis severity; TGCT cis rs7824557 0.564 rs2437152 chr8:11235497 G/A cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.95e-9 Retinal vascular caliber; TGCT cis rs56104184 0.779 rs17206686 chr19:49356317 A/G cg21252483 chr19:49399788 TULP2 -0.36 -4.5 -0.37 1.56e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs11711311 1.000 rs9826465 chr3:113432254 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.71 -6.58 -0.51 1.19e-9 IgG glycosylation; TGCT cis rs9467773 0.595 rs9366657 chr6:26434914 C/G cg05738196 chr6:26577821 NA 0.51 5.44 0.44 2.74e-7 Intelligence (multi-trait analysis); TGCT cis rs2070488 0.965 rs1046048 chr3:38524742 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 8.99 0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs7027203 0.595 rs2398876 chr9:96536853 T/C cg14598338 chr9:96623480 NA 0.49 7.07 0.54 1e-10 DNA methylation (variation); TGCT cis rs4478858 0.647 rs4949380 chr1:31764160 A/G cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs1218582 0.774 rs4845679 chr1:154861187 G/T cg09359103 chr1:154839909 KCNN3 -0.73 -15.86 -0.82 1.28e-31 Prostate cancer; TGCT trans rs1814175 0.647 rs4881649 chr11:49845560 A/G cg03929089 chr4:120376271 NA -0.58 -6.73 -0.52 5.65e-10 Height; TGCT cis rs7584330 0.744 rs10929234 chr2:238380034 C/G cg14458575 chr2:238380390 NA -0.62 -9.64 -0.65 9.41e-17 Prostate cancer; TGCT cis rs7959452 0.562 rs11177630 chr12:69767963 G/C cg14784868 chr12:69753453 YEATS4 0.83 8.85 0.62 7.59e-15 Blood protein levels; TGCT cis rs3008870 0.755 rs2065002 chr1:67487119 A/C cg08660285 chr1:67390436 MIER1;WDR78 -0.78 -8.26 -0.6 1.84e-13 Lymphocyte percentage of white cells; TGCT cis rs2153535 0.580 rs6914276 chr6:8450435 A/T cg07606381 chr6:8435919 SLC35B3 -0.52 -4.88 -0.4 3.18e-6 Motion sickness; TGCT cis rs2657888 0.529 rs118166110 chr12:56887783 G/A cg23002907 chr12:56915593 RBMS2 -0.37 -4.66 -0.39 7.9e-6 Adiponectin levels; TGCT cis rs2228479 0.850 rs1800339 chr16:89839637 C/A cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs12765878 0.603 rs10786773 chr10:105644275 A/T cg11005552 chr10:105648138 OBFC1 -0.42 -6.49 -0.5 1.85e-9 Coronary artery disease; TGCT cis rs1538970 0.924 rs1826691 chr1:45881262 A/G cg05343316 chr1:45956843 TESK2 -0.7 -5.77 -0.46 5.93e-8 Platelet count; TGCT cis rs7258465 1.000 rs271621 chr19:18631332 C/A cg06462663 chr19:18546047 ISYNA1 0.22 5.17 0.42 9.29e-7 Breast cancer; TGCT cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs9372253 0.967 rs9400379 chr6:110713783 A/G cg13266496 chr6:110720918 DDO -0.42 -5.18 -0.42 8.77e-7 Platelet distribution width; TGCT cis rs748404 0.660 rs2249952 chr15:43720533 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs7681440 0.904 rs58864428 chr4:90766986 T/C cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs10193935 1.000 rs62144748 chr2:42419468 C/T cg27598129 chr2:42591480 NA -0.39 -5.16 -0.42 9.46e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7714584 1.000 rs61270113 chr5:150226263 G/A cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs5757676 0.858 rs6001585 chr22:39812986 G/T cg02038168 chr22:39784481 NA -0.71 -5.0 -0.41 1.9e-6 IgG glycosylation; TGCT cis rs9534288 0.797 rs1326401 chr13:46571602 A/G cg15192986 chr13:46630673 CPB2 0.52 7.57 0.56 7.35e-12 Blood protein levels; TGCT cis rs12477438 0.765 rs6735801 chr2:99657995 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.26e-12 Chronic sinus infection; TGCT cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg23758822 chr17:41437982 NA 0.65 6.14 0.48 1.04e-8 Menopause (age at onset); TGCT cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2816958 0.803 rs2821337 chr1:200097743 A/G cg07971716 chr1:199773294 NA 0.46 4.52 0.38 1.45e-5 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs6570726 0.738 rs4495284 chr6:145916617 T/A cg05347473 chr6:146136440 FBXO30 0.53 4.91 0.4 2.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7677751 0.806 rs7673984 chr4:55088761 C/T cg17187183 chr4:55093834 PDGFRA 0.55 7.01 0.53 1.34e-10 Corneal astigmatism; TGCT cis rs4879913 0.801 rs10758314 chr9:35594724 G/A cg18130437 chr9:35658183 CCDC107;RMRP -0.5 -4.95 -0.41 2.38e-6 Electroencephalogram traits; TGCT cis rs12188164 0.930 rs72717436 chr5:448291 C/A cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs1580019 0.961 rs1610143 chr7:32498331 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.61 0.56 5.93e-12 Cognitive ability; TGCT cis rs9907295 0.688 rs2526327 chr17:34256906 A/G cg24520589 chr17:33415888 RFFL -0.65 -4.48 -0.37 1.68e-5 Fibroblast growth factor basic levels; TGCT cis rs9325144 0.624 rs10783329 chr12:39113951 C/T cg26384229 chr12:38710491 ALG10B -0.62 -5.68 -0.45 8.87e-8 Morning vs. evening chronotype; TGCT cis rs763014 0.898 rs8050792 chr16:656033 T/C cg00908189 chr16:619842 PIGQ 0.86 10.25 0.68 3.12e-18 Height; TGCT cis rs7666738 0.830 rs7674095 chr4:99048158 T/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12422267 0.536 rs58521339 chr12:132609486 T/C cg09764611 chr12:132620959 NA -0.38 -5.71 -0.46 7.88e-8 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs9926296 0.568 rs4420527 chr16:89814188 C/T cg27121462 chr16:89883253 FANCA -0.83 -9.15 -0.63 1.46e-15 Vitiligo; TGCT cis rs1775715 0.677 rs2491272 chr10:32186783 A/G cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs765787 0.530 rs2554454 chr15:45521536 A/G cg24006582 chr15:45444508 DUOX1 -0.26 -5.76 -0.46 6.31e-8 Uric acid levels; TGCT cis rs11098499 0.908 rs28559989 chr4:120386627 C/T cg09307838 chr4:120376055 NA 0.68 6.51 0.5 1.66e-9 Corneal astigmatism; TGCT cis rs2594989 0.943 rs2454509 chr3:11489653 C/T cg00170343 chr3:11313890 ATG7 -0.69 -5.1 -0.42 1.26e-6 Circulating chemerin levels; TGCT cis rs8103278 0.507 rs1865116 chr19:46294510 G/A cg11657440 chr19:46296263 DMWD 0.78 8.52 0.61 4.56e-14 Coronary artery disease; TGCT cis rs57221529 0.766 rs12518859 chr5:587432 C/T cg09021430 chr5:549028 NA -0.37 -4.98 -0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs9611565 0.506 rs2024567 chr22:41699206 G/C cg03806693 chr22:41940476 POLR3H -0.82 -7.85 -0.58 1.7e-12 Vitiligo; TGCT cis rs7267979 1.000 rs6050542 chr20:25318879 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7635838 0.557 rs347615 chr3:11277284 T/A cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs1552244 0.882 rs112621205 chr3:10017916 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs1971762 0.527 rs2365343 chr12:54038149 C/T cg16917193 chr12:54089295 NA -0.98 -11.98 -0.73 1.93e-22 Height; TGCT cis rs6426558 0.537 rs2670462 chr1:227432923 C/G cg10327440 chr1:227177885 CDC42BPA -0.6 -6.93 -0.53 2.03e-10 Neutrophil percentage of white cells; TGCT cis rs9611565 0.512 rs2899349 chr22:42164660 T/C cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg13409248 chr3:40428643 ENTPD3 0.55 4.59 0.38 1.06e-5 Renal cell carcinoma; TGCT cis rs698813 0.674 rs6759891 chr2:44496005 C/T cg00619915 chr2:44497795 NA -0.24 -5.41 -0.44 3.11e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg07424592 chr7:64974309 NA -0.65 -6.34 -0.49 3.89e-9 Calcium levels; TGCT cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg17554472 chr22:41940697 POLR3H -0.49 -5.06 -0.41 1.46e-6 Vitiligo; TGCT cis rs4455778 0.580 rs62454353 chr7:49087900 C/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg14159672 chr1:205819179 PM20D1 0.72 9.93 0.67 1.88e-17 Menarche (age at onset); TGCT cis rs1372520 0.808 rs1372518 chr4:90757294 A/C cg15133208 chr4:90757351 SNCA -0.47 -5.34 -0.43 4.3e-7 Neuroticism; TGCT cis rs3806843 1.000 rs10057161 chr5:140156831 C/T cg19875535 chr5:140030758 IK 0.37 6.33 0.49 4.09e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs10883723 0.810 rs6584507 chr10:104254623 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg11211951 chr8:145729740 GPT 0.23 5.5 0.44 2.09e-7 Age at first birth; TGCT cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg12310025 chr6:25882481 NA -0.48 -4.79 -0.4 4.63e-6 Height; TGCT cis rs3096299 0.933 rs747485 chr16:89474094 T/C cg06640241 chr16:89574553 SPG7 0.66 6.39 0.5 3.06e-9 Multiple myeloma (IgH translocation); TGCT cis rs7647973 1.000 rs892974 chr3:49398514 C/A cg06212747 chr3:49208901 KLHDC8B 0.6 4.71 0.39 6.54e-6 Menarche (age at onset); TGCT cis rs523522 0.962 rs603574 chr12:120998443 A/G cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs7044106 0.762 rs1547268 chr9:123408688 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.75 0.39 5.55e-6 Hip circumference adjusted for BMI; TGCT cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs11190604 0.943 rs2495744 chr10:102329409 C/T cg16342193 chr10:102329863 NA -0.42 -5.35 -0.43 4.16e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs17376456 1.000 rs13154249 chr5:93550508 C/T cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.96e-12 Diabetic retinopathy; TGCT cis rs9611565 0.918 rs6002351 chr22:41757223 C/T cg03806693 chr22:41940476 POLR3H -1.02 -11.06 -0.7 3.31e-20 Vitiligo; TGCT cis rs77106637 1.000 rs76793820 chr11:72619860 G/A cg03713592 chr11:72463424 ARAP1 0.83 5.43 0.44 2.87e-7 Type 2 diabetes; TGCT cis rs3806843 1.000 rs3733708 chr5:140181734 A/G cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4629710 0.592 rs13200165 chr6:131549167 G/C cg12606694 chr6:131520996 AKAP7 0.39 4.63 0.38 9.14e-6 Multiple myeloma (IgH translocation); TGCT cis rs3796352 1.000 rs114562844 chr3:52991584 C/T cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7666738 0.606 rs3846446 chr4:99099768 C/A cg17366294 chr4:99064904 C4orf37 0.53 4.9 0.4 2.89e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.791 rs448939 chr6:145808320 T/C cg23711669 chr6:146136114 FBXO30 0.76 7.2 0.54 5.03e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs1153858 0.945 rs7182300 chr15:45634928 G/A cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs6089829 0.888 rs4809467 chr20:61671688 A/G cg18188782 chr20:61659543 NA 0.44 4.88 0.4 3.17e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs2841277 0.645 rs28380382 chr14:105410827 C/T cg19901468 chr14:105411992 AHNAK2 -0.27 -5.76 -0.46 6.14e-8 Rheumatoid arthritis; TGCT cis rs2072499 0.932 rs3001790 chr1:156165290 T/G cg06970220 chr1:156163860 SLC25A44 0.71 6.27 0.49 5.6e-9 Testicular germ cell tumor; TGCT cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg12756686 chr19:29218302 NA 0.78 6.68 0.51 7.13e-10 Methadone dose in opioid dependence; TGCT cis rs4665809 1.000 rs4665309 chr2:26335502 T/C cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs12497850 1.000 rs12497850 chr3:48748989 G/T cg16497277 chr3:49208875 KLHDC8B -0.5 -4.78 -0.39 4.87e-6 Parkinson's disease; TGCT cis rs682748 0.846 rs1964566 chr5:17143610 C/T cg23987134 chr5:17158319 LOC285696 0.21 5.12 0.42 1.15e-6 Hippocampal atrophy; TGCT cis rs716316 1.000 rs716316 chr20:14908741 C/T cg04470754 chr20:14904432 MACROD2 0.34 5.03 0.41 1.67e-6 Advanced glycation end-product levels; TGCT cis rs1878931 1.000 rs1878931 chr16:3450907 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.96 10.59 0.69 4.56e-19 Body mass index (adult); TGCT cis rs6500602 0.627 rs860891 chr16:4586529 C/T cg06139259 chr16:4526053 HMOX2;NMRAL1 -0.27 -4.9 -0.4 2.87e-6 Schizophrenia; TGCT cis rs6460942 0.908 rs6979046 chr7:12232744 A/G cg06484146 chr7:12443880 VWDE -0.52 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs36405 1.000 rs36409 chr14:72357200 C/T cg10066683 chr14:71515513 PCNX 0.24 4.7 0.39 6.69e-6 Yang-deficiency constitution; TGCT cis rs3125734 0.633 rs1368157 chr10:64001114 T/C cg19640130 chr10:64028056 RTKN2 -0.39 -5.02 -0.41 1.78e-6 Rheumatoid arthritis; TGCT cis rs7769051 0.711 rs9493436 chr6:133088275 T/C cg07930552 chr6:133119739 C6orf192 0.87 4.55 0.38 1.27e-5 Type 2 diabetes nephropathy; TGCT cis rs916888 0.773 rs199457 chr17:44795469 C/T cg01570182 chr17:44337453 NA 1.09 9.86 0.66 2.72e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs78487399 0.808 rs6737882 chr2:43731908 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.65 0.39 8.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11031096 0.727 rs7932702 chr11:4124372 C/T cg18678763 chr11:4115507 RRM1 -0.5 -6.56 -0.51 1.34e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs34526934 0.608 rs7591820 chr2:177028144 G/T cg26754761 chr2:177040938 NA -0.28 -5.22 -0.42 7.15e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs28595532 0.748 rs72670248 chr4:119335536 A/C cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs7729723 0.591 rs11242426 chr5:137817243 T/C cg19169342 chr5:137827400 NA 0.35 4.99 0.41 1.97e-6 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs344364 0.511 rs2982453 chr16:1949520 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs597539 0.652 rs569777 chr11:68706848 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.82 7.52 0.56 9.42e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1971762 0.522 rs10747680 chr12:54077776 T/G cg16917193 chr12:54089295 NA 1.37 17.65 0.85 1.25e-35 Height; TGCT cis rs2439831 0.867 rs16957632 chr15:43642897 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs11249608 0.548 rs6867208 chr5:178455575 G/A cg01312482 chr5:178451176 ZNF879 -0.49 -4.76 -0.39 5.2e-6 Pubertal anthropometrics; TGCT cis rs2836974 0.563 rs997147 chr21:40695325 A/G cg17971929 chr21:40555470 PSMG1 -0.68 -5.99 -0.47 2.08e-8 Cognitive function; TGCT cis rs7027203 0.538 rs2244395 chr9:96520723 A/G cg13679303 chr9:96623674 NA -0.53 -7.48 -0.56 1.18e-11 DNA methylation (variation); TGCT cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg06238570 chr21:40685208 BRWD1 0.82 8.95 0.63 4.29e-15 Cognitive function; TGCT cis rs40363 1.000 rs1690443 chr16:3517787 C/G cg05754148 chr16:3507555 NAT15 0.46 4.56 0.38 1.22e-5 Tuberculosis; TGCT cis rs769267 0.965 rs2965198 chr19:19473030 A/G cg03709012 chr19:19516395 GATAD2A -0.77 -6.35 -0.5 3.64e-9 Tonsillectomy; TGCT cis rs12497850 0.931 rs7626445 chr3:49114544 C/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.66 0.45 9.84e-8 Parkinson's disease; TGCT cis rs10540 1.000 rs116876680 chr11:517473 G/T cg03934478 chr11:495069 RNH1 0.32 4.82 0.4 4.16e-6 Body mass index; TGCT cis rs748404 0.660 rs2467742 chr15:43750237 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.71 0.39 6.65e-6 Lung cancer; TGCT cis rs3749237 0.595 rs4855864 chr3:49521974 C/T cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs7698623 0.702 rs1599722 chr4:88782786 A/G cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs5769765 0.862 rs138857 chr22:50199589 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.36 5.26 0.43 6.2e-7 Schizophrenia; TGCT cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs9388451 0.874 rs1159974 chr6:126090277 C/T cg10911889 chr6:126070802 HEY2 -0.55 -5.76 -0.46 6.23e-8 Brugada syndrome; TGCT cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg11494091 chr17:61959527 GH2 0.43 7.4 0.55 1.84e-11 Height; TGCT cis rs13191362 1.000 rs13195226 chr6:163006421 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs8014204 0.836 rs888413 chr14:75267396 C/T cg06637938 chr14:75390232 RPS6KL1 0.64 6.12 0.48 1.13e-8 Caffeine consumption; TGCT cis rs4845570 1.000 rs6683364 chr1:151746202 T/A cg07092448 chr1:151763213 TDRKH -1.12 -8.18 -0.59 2.84e-13 Coronary artery disease; TGCT cis rs11031096 0.535 rs10767886 chr11:4218391 T/C cg18678763 chr11:4115507 RRM1 -0.43 -5.52 -0.44 1.92e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9911578 0.967 rs2643124 chr17:56741672 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs73110464 0.609 rs6580923 chr12:53358352 A/G cg25025879 chr12:53359317 NA -0.52 -5.7 -0.46 8.29e-8 Cancer (pleiotropy); TGCT cis rs7819412 0.643 rs7829396 chr8:10999583 C/T cg21775007 chr8:11205619 TDH -0.55 -5.05 -0.41 1.53e-6 Triglycerides; TGCT cis rs7587476 0.765 rs2121284 chr2:215656260 T/C cg04004882 chr2:215674386 BARD1 -0.62 -4.73 -0.39 6.11e-6 Neuroblastoma; TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs2249625 0.545 rs2249021 chr6:72889472 A/G cg08500200 chr6:72892038 RIMS1 -0.42 -4.55 -0.38 1.27e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg12310025 chr6:25882481 NA -1.13 -14.49 -0.79 1.86e-28 Urate levels; TGCT cis rs514406 0.763 rs7535088 chr1:53215042 A/G cg16325326 chr1:53192061 ZYG11B -0.74 -9.11 -0.63 1.79e-15 Monocyte count; TGCT cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg07061783 chr6:25882402 NA -0.64 -6.06 -0.48 1.53e-8 Intelligence (multi-trait analysis); TGCT cis rs7095607 0.842 rs2130097 chr10:69919422 A/T cg18986048 chr10:69913749 MYPN 0.41 4.48 0.37 1.66e-5 Lung function (FVC); TGCT cis rs1982963 1.000 rs10139288 chr14:52506486 T/C cg10843707 chr14:52510701 NID2 -0.43 -6.6 -0.51 1.09e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7172809 0.573 rs11853633 chr15:77466024 T/C cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs28595532 0.841 rs114768988 chr4:119744451 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9291683 0.538 rs11727199 chr4:10036190 C/T cg00071950 chr4:10020882 SLC2A9 0.68 8.74 0.62 1.35e-14 Bone mineral density; TGCT cis rs17376456 1.000 rs17323433 chr5:93551028 G/A cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg10108389 chr3:44770937 ZNF501 -0.49 -4.9 -0.4 2.96e-6 Depressive symptoms; TGCT cis rs3796352 1.000 rs34340609 chr3:53077276 A/G cg15956490 chr3:53032818 SFMBT1 0.53 6.11 0.48 1.19e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4664308 1.000 rs56297666 chr2:160902023 G/C cg03641300 chr2:160917029 PLA2R1 -0.27 -6.57 -0.51 1.27e-9 Idiopathic membranous nephropathy; TGCT cis rs6089584 0.854 rs8117075 chr20:60613766 T/C cg13665807 chr20:60559372 TAF4 -0.46 -4.94 -0.41 2.48e-6 Body mass index; TGCT cis rs6089829 0.925 rs11086152 chr20:61664656 T/C cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs6558530 0.965 rs7460287 chr8:1708274 G/C cg09410841 chr8:1729607 CLN8 0.91 10.31 0.68 2.23e-18 Systolic blood pressure; TGCT cis rs1670533 1.000 rs6812596 chr4:1069866 A/G cg27284194 chr4:1044797 NA 0.69 5.94 0.47 2.66e-8 Recombination rate (females); TGCT cis rs1577917 0.958 rs6921315 chr6:86471668 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.18 -0.42 8.84e-7 Response to antipsychotic treatment; TGCT cis rs9534288 0.797 rs2404729 chr13:46617368 C/T cg15192986 chr13:46630673 CPB2 -0.4 -5.52 -0.44 1.9e-7 Blood protein levels; TGCT cis rs9527 0.518 rs7899608 chr10:104727304 C/T cg15744005 chr10:104629667 AS3MT -0.6 -4.84 -0.4 3.71e-6 Arsenic metabolism; TGCT cis rs2046867 0.818 rs62251647 chr3:72805789 G/A cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.791 rs28858828 chr4:98950442 C/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg02891314 chr5:179741120 GFPT2 -0.41 -7.06 -0.54 1.04e-10 Height; TGCT cis rs2463822 0.583 rs72919467 chr11:62040102 G/A cg06239285 chr11:62104954 ASRGL1 -0.88 -5.49 -0.44 2.15e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs4237845 0.551 rs116263297 chr12:58273445 A/C cg23860436 chr12:58378763 NA 0.33 4.54 0.38 1.32e-5 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.764 rs367065 chr6:145882309 T/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT trans rs10506458 1.000 rs1009539 chr12:63414655 A/G cg22491629 chr6:157744540 C6orf35 0.99 8.53 0.61 4.35e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs4478858 0.735 rs10914360 chr1:31817476 G/A cg00250761 chr1:31883323 NA -0.27 -4.9 -0.4 2.92e-6 Alcohol dependence; TGCT cis rs6964587 0.967 rs34344935 chr7:91835436 G/A cg17063962 chr7:91808500 NA 0.91 9.26 0.64 7.79e-16 Breast cancer; TGCT cis rs66573146 0.539 rs56659624 chr4:7069377 G/C cg02503808 chr4:7069936 GRPEL1 -0.9 -4.56 -0.38 1.2e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2677744 0.719 rs2002739 chr15:91452106 C/T cg22570213 chr15:91497863 RCCD1 0.39 4.52 0.38 1.4e-5 Attention deficit hyperactivity disorder; TGCT cis rs7731657 0.537 rs10053245 chr5:130353033 G/A cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs7666738 0.830 rs4699331 chr4:99059816 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2230307 0.536 rs11166385 chr1:100443462 A/G cg24955406 chr1:100503596 HIAT1 0.75 4.88 0.4 3.2e-6 Carotid intima media thickness; TGCT cis rs889312 0.500 rs252906 chr5:56119190 G/T cg24531977 chr5:56204891 C5orf35 -0.52 -5.33 -0.43 4.49e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs236907 0.859 rs17649609 chr1:171738453 G/A cg20598894 chr1:171756153 METTL13 -0.19 -4.49 -0.37 1.61e-5 Mean platelet volume; TGCT cis rs6570726 0.791 rs4332001 chr6:145934841 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.61 0.38 9.8200000000000008e-06 Lobe attachment (rater-scored or self-reported); TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg14893161 chr1:205819251 PM20D1 0.54 7.19 0.54 5.3e-11 Menarche (age at onset); TGCT cis rs7267979 0.586 rs6083776 chr20:25186116 G/A cg14121845 chr20:25566513 NINL 0.45 4.86 0.4 3.51e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs911263 0.603 rs3784109 chr14:68789911 T/G cg18825221 chr14:68749962 RAD51L1 0.22 4.5 0.37 1.52e-5 Primary biliary cholangitis; TGCT cis rs9814567 1.000 rs4955485 chr3:134295843 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.98 -7.22 -0.54 4.68e-11 Gut microbiome composition (summer); TGCT cis rs3820068 0.608 rs58140482 chr1:16043979 A/G cg17385448 chr1:15911702 AGMAT 0.36 4.92 0.4 2.67e-6 Systolic blood pressure; TGCT cis rs4148883 0.645 rs2851287 chr4:100014548 G/A cg12011299 chr4:100065546 ADH4 0.4 5.89 0.47 3.32e-8 Alcohol dependence; TGCT cis rs4851254 0.660 rs77023845 chr2:100712346 G/A cg22139774 chr2:100720529 AFF3 -0.41 -4.52 -0.38 1.41e-5 Intelligence (multi-trait analysis); TGCT cis rs9300255 0.506 rs61388686 chr12:123810873 G/A cg00376283 chr12:123451042 ABCB9 0.62 5.29 0.43 5.46e-7 Neutrophil percentage of white cells; TGCT cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT trans rs7615952 0.932 rs11922218 chr3:125631289 C/T cg07211511 chr3:129823064 LOC729375 -0.45 -7.36 -0.55 2.2e-11 Blood pressure (smoking interaction); TGCT cis rs2404602 0.536 rs12915248 chr15:76765615 A/T cg26408565 chr15:76604113 ETFA -0.36 -4.93 -0.4 2.62e-6 Blood metabolite levels; TGCT cis rs877282 0.898 rs10904547 chr10:766283 C/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs57994353 0.568 rs10747044 chr9:139319129 G/T cg13741927 chr9:139327495 INPP5E -0.24 -5.63 -0.45 1.14e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs61677309 1.000 rs1599809 chr11:118179200 G/A cg11038285 chr11:118016290 SCN4B -0.49 -4.52 -0.38 1.41e-5 Lung cancer in ever smokers; TGCT cis rs17102423 0.559 rs7160037 chr14:65490948 T/C cg11161011 chr14:65562177 MAX -0.46 -5.33 -0.43 4.45e-7 Obesity-related traits; TGCT cis rs9677476 0.516 rs6706191 chr2:232040047 T/G cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs7959452 0.562 rs10878975 chr12:69782044 G/C cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg06618935 chr21:46677482 NA -0.37 -5.83 -0.46 4.48e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2840044 1.000 rs225277 chr17:33973311 G/A cg05299278 chr17:33885742 SLFN14 0.22 4.98 0.41 2.07e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs589448 1.000 rs589448 chr12:69752200 A/G cg14784868 chr12:69753453 YEATS4 0.89 10.43 0.68 1.11e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs62064224 0.791 rs11654833 chr17:30667728 C/T cg18200150 chr17:30822561 MYO1D 0.59 7.64 0.57 5.14e-12 Schizophrenia; TGCT cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg18765753 chr7:1198926 ZFAND2A -0.49 -5.82 -0.46 4.68e-8 Longevity;Endometriosis; TGCT cis rs7666738 0.830 rs35644814 chr4:98886111 G/C cg18180107 chr4:99064573 C4orf37 0.53 4.84 0.4 3.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs13168506 0.552 rs889010 chr5:135572910 C/A cg16684184 chr5:135415129 NA 0.25 4.76 0.39 5.4e-6 Stroke; TGCT cis rs9868809 0.505 rs13316551 chr3:48745167 A/C cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs35934224 0.783 rs34675706 chr22:19847618 G/A cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT trans rs877282 0.891 rs34383514 chr10:800181 T/C cg22713356 chr15:30763199 NA 1.18 9.92 0.67 1.96e-17 Uric acid levels; TGCT cis rs7095607 0.785 rs4746731 chr10:69920924 C/A cg18986048 chr10:69913749 MYPN 0.41 4.48 0.37 1.66e-5 Lung function (FVC); TGCT cis rs514406 0.763 rs7535088 chr1:53215042 A/G cg08736216 chr1:53307985 ZYG11A 0.25 4.77 0.39 4.98e-6 Monocyte count; TGCT cis rs4767364 0.961 rs10850024 chr12:112718510 C/A cg10833066 chr12:111807467 FAM109A 0.33 5.13 0.42 1.08e-6 Oral cavity and pharyngeal cancer; TGCT cis rs427394 0.802 rs274721 chr5:6719164 C/T cg10857441 chr5:6722123 POLS -0.32 -7.8 -0.57 2.17e-12 Menopause (age at onset); TGCT cis rs7044106 0.708 rs1324472 chr9:123375110 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.58 6.29 0.49 5.01e-9 Hip circumference adjusted for BMI; TGCT cis rs4862750 0.914 rs1863405 chr4:187874528 G/T cg11301795 chr4:187892539 NA 0.35 5.35 0.43 4.08e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6674176 0.569 rs34830883 chr1:44405339 T/C cg13606994 chr1:44402422 ARTN -0.53 -5.69 -0.46 8.53e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9372498 0.536 rs724868 chr6:118795152 C/T cg21191810 chr6:118973309 C6orf204 -0.37 -4.76 -0.39 5.36e-6 Diastolic blood pressure; TGCT cis rs1577917 0.727 rs9444361 chr6:86400900 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.57 5.13 0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs362272 0.524 rs13150241 chr4:3367281 A/G cg06533319 chr4:3265114 C4orf44 -0.28 -5.69 -0.46 8.58e-8 Serum sulfate level; TGCT cis rs71636778 0.509 rs17356923 chr1:27282676 G/A cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.69 0.39 7.09e-6 Vitiligo; TGCT cis rs9486715 0.867 rs9373829 chr6:96897201 A/C cg06623918 chr6:96969491 KIAA0776 -1.07 -15.72 -0.82 2.66e-31 Headache; TGCT cis rs4499344 0.604 rs259245 chr19:33145106 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.76 7.52 0.56 9.49e-12 Mean platelet volume; TGCT trans rs7618501 0.633 rs6772095 chr3:49978069 C/T cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.6e-16 Intelligence (multi-trait analysis); TGCT cis rs9372253 1.000 rs7740028 chr6:110719180 A/G cg01119278 chr6:110721349 DDO -0.37 -5.92 -0.47 2.88e-8 Platelet distribution width; TGCT cis rs6951245 0.554 rs78999139 chr7:1138525 G/A cg23708337 chr7:1209742 NA 0.44 4.87 0.4 3.27e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12776158 0.901 rs59262400 chr10:71216310 G/A cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs910316 0.934 rs7141705 chr14:75655352 G/C cg11812906 chr14:75593930 NEK9 -0.71 -6.83 -0.52 3.43e-10 Height; TGCT cis rs7772486 0.719 rs7753770 chr6:146066161 G/A cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs7394190 0.748 rs34163229 chr10:75406912 G/T cg07699608 chr10:75541558 CHCHD1 0.6 4.49 0.37 1.59e-5 Incident atrial fibrillation; TGCT cis rs6121246 0.529 rs6060291 chr20:30198043 T/G cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs9914544 1.000 rs1037036 chr17:18764077 C/T cg26378065 chr17:18585709 ZNF286B 0.51 4.57 0.38 1.17e-5 Educational attainment (years of education); TGCT cis rs11098499 0.863 rs1383532 chr4:120434404 A/T cg09307838 chr4:120376055 NA -0.71 -6.43 -0.5 2.53e-9 Corneal astigmatism; TGCT cis rs916888 0.821 rs199512 chr17:44857352 T/C cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 0.554 rs17802082 chr8:58095867 C/T cg20607798 chr8:58055168 NA 0.7 5.94 0.47 2.66e-8 Developmental language disorder (linguistic errors); TGCT trans rs9951602 0.512 rs1599634 chr18:76643645 T/C cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs938554 0.735 rs11942223 chr4:9962765 T/C cg11197905 chr4:10459435 ZNF518B -0.29 -4.44 -0.37 1.98e-5 Blood metabolite levels; TGCT cis rs885389 1.000 rs867411 chr12:131621789 T/G cg07124762 chr12:131619285 GPR133 -0.31 -6.33 -0.49 4.15e-9 RR interval (heart rate); TGCT cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg12310025 chr6:25882481 NA -0.59 -6.04 -0.48 1.63e-8 Blood metabolite levels; TGCT trans rs208520 0.690 rs12213561 chr6:66705646 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs4780355 1.000 rs4780355 chr16:11347858 T/C cg00044050 chr16:11439710 C16orf75 0.55 4.78 0.39 4.93e-6 Crohn's disease and psoriasis; TGCT cis rs473651 0.904 rs10929275 chr2:239323169 A/G cg18131467 chr2:239335373 ASB1 0.99 13.63 0.77 2.02e-26 Multiple system atrophy; TGCT cis rs1580019 0.563 rs4723169 chr7:32567577 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 14.94 0.8 1.6800000000000001e-29 Cognitive ability; TGCT cis rs6951245 0.554 rs11761322 chr7:1151657 A/G cg09177884 chr7:1199841 ZFAND2A -0.69 -5.47 -0.44 2.41e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9583531 0.527 rs6492302 chr13:111352354 C/T cg24331049 chr13:111365604 ING1 -0.75 -7.31 -0.55 2.9100000000000002e-11 Coronary artery disease; TGCT cis rs12893668 0.703 rs35498576 chr14:104025893 T/C cg26031613 chr14:104095156 KLC1 -0.54 -4.55 -0.38 1.28e-5 Reticulocyte count; TGCT cis rs72634258 0.554 rs4908704 chr1:7918904 A/G cg26816564 chr1:7831052 VAMP3 0.64 4.94 0.41 2.46e-6 Inflammatory bowel disease; TGCT cis rs4499344 0.633 rs259282 chr19:33163043 C/T cg26639809 chr19:33781782 NA 0.22 4.56 0.38 1.22e-5 Mean platelet volume; TGCT cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 8.79 0.62 1.01e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT cis rs78487399 0.731 rs6747229 chr2:43712610 T/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -4.95 -0.41 2.34e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12541335 0.590 rs11136002 chr8:22217082 C/T cg09517075 chr8:22133004 PIWIL2 0.25 4.76 0.39 5.21e-6 Hypertriglyceridemia; TGCT cis rs2404602 0.563 rs12914005 chr15:76765667 A/G cg22467129 chr15:76604101 ETFA -0.48 -6.01 -0.48 1.91e-8 Blood metabolite levels; TGCT cis rs4888262 0.526 rs4887772 chr16:74537591 C/T cg01733217 chr16:74700730 RFWD3 0.68 6.88 0.53 2.6200000000000003e-10 Testicular germ cell tumor; TGCT cis rs7829975 0.533 rs1039917 chr8:8718850 C/T cg15556689 chr8:8085844 FLJ10661 0.78 7.48 0.56 1.21e-11 Mood instability; TGCT cis rs6582630 0.519 rs11495724 chr12:38337507 T/C cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs6061231 0.631 rs2427318 chr20:60975727 G/T cg24112000 chr20:60950667 NA -0.35 -4.91 -0.4 2.77e-6 Colorectal cancer; TGCT cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg10263370 chr3:44754102 ZNF502 -0.4 -4.8 -0.4 4.4e-6 Depressive symptoms; TGCT cis rs10465746 0.725 rs12070578 chr1:84349607 A/G cg10977910 chr1:84465055 TTLL7 0.68 6.7 0.52 6.46e-10 Obesity-related traits; TGCT cis rs2456568 0.867 rs10501810 chr11:93666589 C/G cg17595323 chr11:93583763 C11orf90 -0.45 -5.85 -0.46 4.13e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1577917 0.876 rs12190735 chr6:86686467 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -4.94 -0.41 2.43e-6 Response to antipsychotic treatment; TGCT cis rs7178572 0.524 rs1473922 chr15:77656798 G/T cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs875971 0.862 rs17747530 chr7:65994729 G/C cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs7829975 0.744 rs2409092 chr8:8682192 A/T cg15556689 chr8:8085844 FLJ10661 0.69 6.43 0.5 2.56e-9 Mood instability; TGCT cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg21724239 chr8:58056113 NA 0.47 5.05 0.41 1.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs700651 0.753 rs10207232 chr2:198893813 A/G cg00792783 chr2:198669748 PLCL1 0.59 5.19 0.42 8.27e-7 Intracranial aneurysm; TGCT cis rs3087591 0.960 rs11080146 chr17:29578724 C/T cg24425628 chr17:29625626 OMG;NF1 -0.46 -7.19 -0.54 5.31e-11 Hip circumference; TGCT cis rs2243480 1.000 rs465359 chr7:65558164 C/T cg07424592 chr7:64974309 NA 1.26 8.11 0.59 4.17e-13 Diabetic kidney disease; TGCT cis rs892961 0.932 rs8066646 chr17:75414192 C/T cg05865280 chr17:75406074 SEPT9 0.28 6.71 0.52 6.16e-10 Airflow obstruction; TGCT cis rs2228479 0.850 rs11639788 chr16:89807543 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs6815814 0.861 rs73142654 chr4:38785697 T/A cg02016764 chr4:38805732 TLR1 -0.27 -4.46 -0.37 1.78e-5 Breast cancer; TGCT cis rs7209700 0.547 rs16941776 chr17:45343141 C/T cg21624342 chr17:45890973 OSBPL7 0.19 4.77 0.39 5.02e-6 IgG glycosylation; TGCT cis rs6977660 0.507 rs72591448 chr7:19775298 C/T cg07541023 chr7:19748670 TWISTNB 0.98 6.33 0.49 4.02e-9 Thyroid stimulating hormone; TGCT cis rs16910800 0.731 rs55908012 chr11:23191640 G/A cg20040320 chr11:23191996 NA -0.51 -4.47 -0.37 1.71e-5 Cancer; TGCT cis rs1941023 0.584 rs6591578 chr11:60158649 G/A cg08716584 chr11:60157161 MS4A7 -0.32 -4.92 -0.4 2.7e-6 Congenital heart disease (maternal effect); TGCT cis rs7617773 0.638 rs7644414 chr3:48299079 A/T cg11946769 chr3:48343235 NME6 0.69 5.64 0.45 1.1e-7 Coronary artery disease; TGCT cis rs597539 0.652 rs514296 chr11:68654182 G/T cg06112835 chr11:68658793 MRPL21 0.46 8.07 0.59 5.25e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg17554472 chr22:41940697 POLR3H 0.49 5.07 0.41 1.38e-6 Vitiligo; TGCT cis rs12681287 0.609 rs13279850 chr8:87477800 C/T cg27223183 chr8:87520930 FAM82B -0.84 -6.11 -0.48 1.19e-8 Caudate activity during reward; TGCT cis rs1538970 0.810 rs12067642 chr1:45927517 G/T cg05343316 chr1:45956843 TESK2 0.79 6.38 0.5 3.23e-9 Platelet count; TGCT cis rs240764 0.697 rs846799 chr6:101270345 A/G cg21058520 chr6:100914733 NA -0.35 -4.56 -0.38 1.22e-5 Neuroticism; TGCT cis rs3733631 1.000 rs6831087 chr4:104619090 C/A cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT cis rs1843834 0.539 rs6749402 chr2:225443901 T/G cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs7647973 0.626 rs2329021 chr3:49679072 G/A cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs433852 0.718 rs386551 chr19:49138286 C/G cg07996880 chr19:49339085 HSD17B14 -0.28 -4.69 -0.39 7.03e-6 Elevated serum carcinoembryonic antigen levels;Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs17539620 0.534 rs7768635 chr6:154827861 C/T cg17771515 chr6:154831774 CNKSR3 0.67 4.6 0.38 1.02e-5 Lipoprotein (a) levels; TGCT cis rs7945705 0.935 rs11042103 chr11:8888700 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.42 4.73 0.39 5.99e-6 Hemoglobin concentration; TGCT cis rs6121246 0.609 rs6060948 chr20:30376393 C/G cg10886678 chr20:30946050 ASXL1 -0.53 -4.5 -0.37 1.55e-5 Mean corpuscular hemoglobin; TGCT cis rs72647484 0.730 rs72647483 chr1:22587009 T/C cg21876283 chr1:22149684 LDLRAD2;HSPG2 0.27 4.52 0.38 1.42e-5 Colorectal cancer; TGCT cis rs3806843 0.735 rs778597 chr5:140040665 A/G cg19875535 chr5:140030758 IK 0.37 6.28 0.49 5.14e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7698623 0.850 rs10011586 chr4:88798921 C/T cg27387453 chr4:88533842 DSPP -0.6 -4.53 -0.38 1.35e-5 Cardiovascular disease risk factors; TGCT cis rs9322193 0.923 rs9767123 chr6:149981459 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs9916302 0.904 rs68178216 chr17:37526241 A/C cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs1018836 0.923 rs34126139 chr8:91572045 T/G cg16814680 chr8:91681699 NA -0.88 -9.4 -0.65 3.57e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10479542 0.806 rs4700836 chr5:178976393 A/G cg19723775 chr5:179050963 HNRNPH1 0.48 4.64 0.38 8.71e-6 Lung cancer; TGCT cis rs10875746 0.903 rs12306451 chr12:48483241 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs9906944 0.707 rs4794019 chr17:47107290 G/T cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.76 -0.39 5.4e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs1215050 0.791 rs165242 chr4:98686482 A/C cg05340658 chr4:99064831 C4orf37 -0.44 -5.18 -0.42 8.76e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10782582 0.609 rs6656501 chr1:76266126 A/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs11644362 1.000 rs4781349 chr16:12987249 T/C cg06890432 chr16:12997467 SHISA9 -0.6 -6.49 -0.5 1.88e-9 Positive affect;Subjective well-being; TGCT cis rs6598541 0.505 rs2175795 chr15:99312854 A/G cg18742785 chr15:100270048 LYSMD4 -0.26 -4.55 -0.38 1.25e-5 Urate levels; TGCT cis rs6500602 0.647 rs4786519 chr16:4584406 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs270601 0.913 rs273916 chr5:131659830 C/A cg24060327 chr5:131705240 SLC22A5 -0.74 -7.96 -0.58 9.5e-13 Acylcarnitine levels; TGCT cis rs9902453 0.868 rs12944395 chr17:28323499 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.33 -0.55 2.6e-11 Coffee consumption (cups per day); TGCT cis rs4819052 0.851 rs8130285 chr21:46671701 G/C cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2180341 1.000 rs7756336 chr6:127650299 T/C cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs4727027 0.901 rs10952792 chr7:148760501 C/T cg23583168 chr7:148888333 NA -0.69 -8.67 -0.61 2.04e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs10992471 0.580 rs10992304 chr9:95085365 G/A cg14631576 chr9:95140430 CENPP -0.3 -4.49 -0.37 1.62e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg03452623 chr4:187889614 NA -0.36 -5.43 -0.44 2.85e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.592 rs57102627 chr22:41987627 T/C cg06634786 chr22:41940651 POLR3H -0.83 -7.66 -0.57 4.6e-12 Vitiligo; TGCT cis rs10791097 0.694 rs7125622 chr11:130743388 T/C cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7772486 0.817 rs2748491 chr6:146327759 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.98 0.41 2.12e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs9329221 0.741 rs13264066 chr8:9804075 C/G cg06636001 chr8:8085503 FLJ10661 -0.77 -6.93 -0.53 2.02e-10 Neuroticism; TGCT cis rs6424115 0.830 rs3003336 chr1:24201448 C/T cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs2836633 0.931 rs2836635 chr21:40069850 A/G cg05519781 chr21:40033154 ERG 0.51 4.97 0.41 2.17e-6 Coronary artery disease; TGCT cis rs62064224 0.702 rs735555 chr17:30817450 A/G cg18200150 chr17:30822561 MYO1D -0.55 -7.33 -0.55 2.65e-11 Schizophrenia; TGCT cis rs459571 0.959 rs456205 chr9:136911146 G/A cg13789015 chr9:136890014 NCRNA00094 0.4 7.15 0.54 6.64e-11 Platelet distribution width; TGCT cis rs9868809 0.505 rs9811027 chr3:48725014 G/C cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7582180 0.614 rs1530030 chr2:101009600 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 6.02e-6 Intelligence (multi-trait analysis); TGCT cis rs1997103 1.000 rs2177802 chr7:55410789 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs228437 0.586 rs7763955 chr6:134939628 C/A cg09872934 chr6:134495829 SGK1 -0.55 -4.65 -0.39 8.39e-6 Melanoma; TGCT cis rs72781680 0.898 rs17762651 chr2:24115922 A/G cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs9341808 0.718 rs9443735 chr6:80820474 G/T cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs7267979 1.000 rs2259837 chr20:25280205 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2702888 0.502 rs2702935 chr8:6751827 A/G cg26795848 chr8:6756730 NA -0.31 -6.13 -0.48 1.1e-8 Blood pressure; TGCT cis rs1005224 0.926 rs12892551 chr14:76159902 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.63 -5.61 -0.45 1.28e-7 Large artery stroke; TGCT cis rs55692411 0.537 rs62262118 chr3:50003586 G/A cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs2075371 1.000 rs2241334 chr7:133979225 C/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.36e-9 Mean platelet volume; TGCT cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1163251 0.837 rs839612 chr1:120247176 T/C cg19096424 chr1:120255104 PHGDH 0.6 5.93 0.47 2.76e-8 Blood metabolite levels; TGCT cis rs861020 0.630 rs616544 chr1:210007368 T/C cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT trans rs8073060 0.586 rs7208672 chr17:33989759 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg10108389 chr3:44770937 ZNF501 -0.48 -4.83 -0.4 4.02e-6 Depressive symptoms; TGCT cis rs9549367 0.774 rs2287246 chr13:113889127 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.49 -0.44 2.18e-7 Platelet distribution width; TGCT cis rs739496 0.579 rs3741998 chr12:112339843 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs1552244 0.882 rs7633769 chr3:10020622 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg21724239 chr8:58056113 NA 0.48 5.17 0.42 9.18e-7 Developmental language disorder (linguistic errors); TGCT cis rs71597109 0.957 rs13136796 chr4:102736743 A/T cg14855874 chr4:102712397 BANK1 0.42 4.47 0.37 1.77e-5 Chronic lymphocytic leukemia; TGCT cis rs7552404 0.883 rs2185436 chr1:76203783 A/G cg10523679 chr1:76189770 ACADM 0.89 9.88 0.66 2.42e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10435719 0.902 rs4840599 chr8:11805380 C/T cg02840367 chr8:11660030 FDFT1 0.54 4.54 0.38 1.31e-5 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs57221529 0.766 rs4081847 chr5:574072 C/T cg09021430 chr5:549028 NA -0.37 -5.29 -0.43 5.46e-7 Lung disease severity in cystic fibrosis; TGCT cis rs136211 0.577 rs9610498 chr22:36777739 C/T cg16924664 chr22:36878180 TXN2 0.51 4.83 0.4 3.99e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9326248 0.501 rs4938351 chr11:117022352 A/C cg01368799 chr11:117014884 PAFAH1B2 0.6 5.6 0.45 1.33e-7 Blood protein levels; TGCT cis rs2760061 0.583 rs708118 chr1:228201801 A/G cg18477163 chr1:228402036 OBSCN -0.32 -6.62 -0.51 9.85e-10 Diastolic blood pressure; TGCT cis rs12368653 0.641 rs11172300 chr12:58076515 C/T cg12615879 chr12:58013172 SLC26A10 0.48 5.76 0.46 6.37e-8 Multiple sclerosis; TGCT cis rs6460942 1.000 rs62448568 chr7:12407445 A/G cg06484146 chr7:12443880 VWDE -0.57 -5.34 -0.43 4.36e-7 Coronary artery disease; TGCT trans rs1005277 0.579 rs2021649 chr10:38392122 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs617219 0.710 rs16876598 chr5:78573970 T/C cg23514016 chr5:78407564 BHMT -0.32 -4.87 -0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg12667521 chr19:29218732 NA 0.51 6.21 0.49 7.46e-9 Methadone dose in opioid dependence; TGCT cis rs3771570 0.892 rs62186433 chr2:242257835 A/G cg21155796 chr2:242212141 HDLBP 0.96 6.36 0.5 3.5e-9 Prostate cancer; TGCT cis rs780096 0.587 rs6743819 chr2:27567407 G/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.36 4.58 0.38 1.12e-5 Total body bone mineral density; TGCT cis rs9303401 0.659 rs35103007 chr17:56900738 G/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs4664308 0.810 rs62175552 chr2:160937220 T/G cg03641300 chr2:160917029 PLA2R1 -0.28 -6.83 -0.52 3.43e-10 Idiopathic membranous nephropathy; TGCT cis rs2243480 0.711 rs2460426 chr7:65623129 A/G cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs739496 0.947 rs2301622 chr12:111895203 C/G cg10833066 chr12:111807467 FAM109A 0.36 5.51 0.44 2.01e-7 Platelet count; TGCT cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg08736216 chr1:53307985 ZYG11A -0.24 -4.74 -0.39 5.75e-6 Monocyte count; TGCT cis rs13256369 0.901 rs13251887 chr8:8568678 G/A cg18904891 chr8:8559673 CLDN23 0.59 5.54 0.45 1.73e-7 Obesity-related traits; TGCT trans rs6089829 0.851 rs6089827 chr20:61668845 C/T cg17470723 chr8:74884337 TCEB1 0.77 7.4 0.55 1.82e-11 Prostate cancer (SNP x SNP interaction); TGCT trans rs1075232 0.677 rs72714666 chr15:31492226 T/C cg18108818 chr7:102574475 FBXL13;LRRC17 0.83 6.81 0.52 3.83e-10 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs12220238 0.841 rs7919010 chr10:76111137 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.87 6.32 0.49 4.31e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9303401 0.659 rs62083436 chr17:57031742 G/A cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs319204 1.000 rs319231 chr5:146242245 C/T cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs929354 0.742 rs7806775 chr7:156947199 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg16325326 chr1:53192061 ZYG11B -0.7 -8.6 -0.61 2.87e-14 Monocyte count; TGCT cis rs6665290 0.901 rs3795453 chr1:227205331 A/G cg10327440 chr1:227177885 CDC42BPA -0.93 -16.65 -0.83 2.06e-33 Myeloid white cell count; TGCT cis rs5769707 0.706 rs763128 chr22:50018045 G/A cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 4.95e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs28594127 chr4:99001121 T/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7044106 0.762 rs3904197 chr9:123480378 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.53 0.51 1.52e-9 Hip circumference adjusted for BMI; TGCT cis rs651907 0.535 rs34648996 chr3:101511202 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs7772486 0.875 rs9390377 chr6:146386932 G/A cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg05785598 chr3:49045655 WDR6 -0.36 -4.68 -0.39 7.35e-6 Menarche (age at onset); TGCT cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg05665937 chr4:1216051 CTBP1 0.25 4.68 0.39 7.33e-6 Obesity-related traits; TGCT cis rs17376456 1.000 rs17376456 chr5:93557702 C/T cg21475434 chr5:93447410 FAM172A -0.63 -4.62 -0.38 9.66e-6 Diabetic retinopathy; TGCT cis rs6540559 0.673 rs11803382 chr1:209986426 G/A cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs4409675 0.597 rs1467464 chr1:28211650 T/C cg23691781 chr1:28212827 C1orf38 0.26 5.27 0.43 5.89e-7 Corneal astigmatism; TGCT cis rs9325144 0.647 rs11169189 chr12:39097078 A/T cg26384229 chr12:38710491 ALG10B -0.51 -4.89 -0.4 3.1e-6 Morning vs. evening chronotype; TGCT cis rs7429990 0.930 rs13072132 chr3:47866161 A/G cg11946769 chr3:48343235 NME6 0.59 4.45 0.37 1.87e-5 Educational attainment (years of education); TGCT cis rs10858047 0.883 rs1564824 chr1:115123747 A/G cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs3617 0.532 rs9836499 chr3:52904524 G/T cg11645453 chr3:52864694 ITIH4 -0.27 -5.16 -0.42 9.4e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2639990 1.000 rs655156 chr18:72898181 T/C cg02750262 chr18:72916776 ZADH2 0.88 6.67 0.51 7.46e-10 Vascular endothelial growth factor levels; TGCT cis rs704 0.739 rs2027993 chr17:26706946 G/T cg10342447 chr17:26645325 TMEM97 -0.48 -4.67 -0.39 7.82e-6 Osteoprotegerin levels; TGCT cis rs2652822 0.504 rs2134263 chr15:63365394 C/T cg12855773 chr15:63363890 TPM1 -0.17 -4.7 -0.39 6.82e-6 Metabolic traits; TGCT cis rs9549367 0.713 rs9577211 chr13:113830718 G/C cg09473364 chr13:112927190 NA -0.3 -4.64 -0.38 8.7e-6 Platelet distribution width; TGCT cis rs2070488 1.000 rs13072809 chr3:38468171 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs33794 0.935 rs33789 chr3:45296367 A/G cg18645101 chr3:44551900 NA 0.53 4.67 0.39 7.84e-6 Lung function (forced expiratory volume in 1 second); TGCT trans rs208520 1.000 rs12190187 chr6:66973207 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.86 7.83 0.58 1.85e-12 Exhaled nitric oxide output; TGCT cis rs2290402 0.572 rs3736087 chr4:876318 C/T cg23332689 chr4:987652 IDUA;SLC26A1 0.36 5.44 0.44 2.77e-7 Type 2 diabetes; TGCT cis rs78487399 0.908 rs12475503 chr2:43831319 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9611519 0.929 rs9611469 chr22:41433319 T/C cg03806693 chr22:41940476 POLR3H -0.7 -6.22 -0.49 6.88e-9 Neuroticism; TGCT trans rs208515 0.592 rs10944862 chr6:66674215 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs597539 0.652 rs636049 chr11:68667198 A/C cg04772025 chr11:68637568 NA 0.59 6.7 0.52 6.48e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12049351 0.675 rs754024 chr1:229637414 C/T cg12130225 chr1:229698885 NA 0.39 4.58 0.38 1.12e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs2677744 0.688 rs7183098 chr15:91452294 A/G cg23684204 chr15:91497937 RCCD1 0.33 4.82 0.4 4.1e-6 Attention deficit hyperactivity disorder; TGCT cis rs9291683 0.588 rs35866697 chr4:10018604 C/A cg11266682 chr4:10021025 SLC2A9 0.73 10.8 0.7 1.4e-19 Bone mineral density; TGCT cis rs7582180 0.675 rs4851313 chr2:101029002 A/G cg08017756 chr2:100939284 LONRF2 0.3 4.52 0.38 1.44e-5 Intelligence (multi-trait analysis); TGCT cis rs17767294 0.708 rs72845897 chr6:27699357 T/C cg08851530 chr6:28072375 NA 1.56 7.38 0.55 1.95e-11 Parkinson's disease; TGCT cis rs7267979 0.789 rs4815400 chr20:25292560 T/C cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7223966 1.000 rs11657306 chr17:61704822 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.17 0.42 9.12e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7528684 0.752 rs2050568 chr1:157770241 C/T cg17134153 chr1:157670328 FCRL3 -0.27 -4.86 -0.4 3.51e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs7267979 0.966 rs6037097 chr20:25347221 C/T cg03522245 chr20:25566470 NINL 0.59 6.21 0.49 7.19e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9296092 0.517 rs78978280 chr6:33520747 T/A cg13560919 chr6:33536144 NA -0.2 -4.64 -0.38 8.68e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs61990749 0.597 rs1048147 chr14:78139988 C/A cg02301378 chr14:78227641 SNW1;C14orf178 -0.61 -4.45 -0.37 1.89e-5 Fibroblast growth factor basic levels; TGCT cis rs896854 0.654 rs28591375 chr8:95973637 C/G cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs2880765 0.835 rs730372 chr15:86038193 G/T cg13263323 chr15:86062960 AKAP13 0.22 4.79 0.4 4.68e-6 Coronary artery disease; TGCT cis rs2299587 0.610 rs7001974 chr8:17773295 C/T cg01800426 chr8:17659068 MTUS1 -0.7 -6.03 -0.48 1.72e-8 Economic and political preferences; TGCT cis rs7809950 1.000 rs10258385 chr7:107243350 T/C cg23024343 chr7:107201750 COG5 0.33 5.29 0.43 5.36e-7 Coronary artery disease; TGCT cis rs7659604 0.539 rs7699776 chr4:122753885 A/G cg20573242 chr4:122745356 CCNA2 0.63 5.59 0.45 1.37e-7 Type 2 diabetes; TGCT cis rs9398235 0.929 rs4945860 chr6:110728383 A/G cg00083206 chr6:110721305 DDO 0.46 4.64 0.38 8.68e-6 Systemic lupus erythematosus; TGCT cis rs2806561 0.704 rs664301 chr1:23522522 C/T cg12483005 chr1:23474871 LUZP1 0.42 5.41 0.44 3.15e-7 Height; TGCT cis rs240764 0.658 rs12213201 chr6:101176285 C/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.46e-5 Neuroticism; TGCT cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg19729930 chr2:74357872 NA 0.65 9.55 0.65 1.56e-16 Gestational age at birth (maternal effect); TGCT cis rs9467773 1.000 rs2208331 chr6:26507319 A/G cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT cis rs910316 1.000 rs12588240 chr14:75612083 C/A cg11812906 chr14:75593930 NEK9 0.74 7.37 0.55 2.12e-11 Height; TGCT cis rs2439831 0.867 rs4583210 chr15:43660925 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs57590327 0.555 rs6767749 chr3:81725513 G/A cg07356753 chr3:81810745 GBE1 -0.77 -7.15 -0.54 6.47e-11 Extraversion; TGCT cis rs137603 0.623 rs470075 chr22:39686806 G/A cg17798944 chr22:39715225 SNORD43;RPL3 -0.68 -6.96 -0.53 1.75e-10 Primary biliary cholangitis; TGCT cis rs752010 0.714 rs2148635 chr1:42082452 C/T cg06885757 chr1:42089581 HIVEP3 -0.25 -4.45 -0.37 1.92e-5 Lupus nephritis in systemic lupus erythematosus; TGCT trans rs1499614 1.000 rs2707828 chr7:66171377 G/A cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg05738196 chr6:26577821 NA 0.88 11.4 0.72 5.07e-21 Intelligence (multi-trait analysis); TGCT cis rs11891 0.685 rs9891726 chr17:76992101 C/T cg25730791 chr17:76457213 DNAH17 0.42 4.76 0.39 5.4e-6 Magnesium levels; TGCT cis rs6582630 0.519 rs12368889 chr12:38315160 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.22 0.54 4.62e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7119038 0.818 rs10892294 chr11:118667357 C/G cg19308663 chr11:118741387 NA -0.29 -5.91 -0.47 3.12e-8 Sjögren's syndrome; TGCT cis rs2663905 0.611 rs2663924 chr15:81392903 T/G cg09236163 chr15:81426669 C15orf26 -0.46 -4.68 -0.39 7.42e-6 QT interval (drug interaction); TGCT trans rs916888 0.610 rs199536 chr17:44820425 T/C cg22433210 chr17:43662623 NA -0.94 -7.99 -0.58 7.87e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs875971 1.000 rs6958484 chr7:65599446 G/A cg11764359 chr7:65958608 NA -0.57 -4.99 -0.41 2.03e-6 Aortic root size; TGCT cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs9399137 0.507 rs13214669 chr6:135299959 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.76 0.39 5.27e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs12477438 0.520 rs11695379 chr2:99742161 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.12 17.33 0.84 6.27e-35 Chronic sinus infection; TGCT cis rs7726839 0.574 rs72705014 chr5:619815 C/G cg16624210 chr5:671434 TPPP 0.43 4.68 0.39 7.5e-6 Obesity-related traits; TGCT cis rs10492096 0.947 rs10849484 chr12:6637941 C/T cg00459232 chr12:6309025 CD9 0.36 4.46 0.37 1.84e-5 Hip geometry; TGCT cis rs28595532 0.920 rs56291421 chr4:119732294 G/A cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT trans rs2727020 0.615 rs35423199 chr11:49514914 T/C cg03929089 chr4:120376271 NA -0.77 -9.31 -0.64 5.82e-16 Coronary artery disease; TGCT cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.58e-9 Gut microbiome composition (summer); TGCT cis rs2066819 1.000 rs78149779 chr12:56694817 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs7833790 1.000 rs7834808 chr8:82704996 A/G cg27398817 chr8:82754497 SNX16 -0.89 -6.25 -0.49 5.89e-9 Diastolic blood pressure; TGCT cis rs7666738 0.830 rs4292341 chr4:98959724 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.1 0.42 1.25e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4845570 0.834 rs1196467 chr1:151710038 T/C cg07092448 chr1:151763213 TDRKH 1.05 8.06 0.59 5.43e-13 Coronary artery disease; TGCT cis rs12681288 0.792 rs12678495 chr8:1000858 C/G cg04851639 chr8:1020857 NA -0.36 -6.43 -0.5 2.55e-9 Schizophrenia; TGCT cis rs911555 0.755 rs12432803 chr14:103930032 C/T cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs1843834 0.716 rs6716600 chr2:225481991 A/T cg22455342 chr2:225449267 CUL3 0.8 8.03 0.58 6.56e-13 IgE levels in asthmatics (D.p. specific); TGCT cis rs6912958 0.781 rs13193380 chr6:88297057 G/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs7914558 0.966 rs7921574 chr10:104840970 T/C cg15744005 chr10:104629667 AS3MT -0.39 -4.69 -0.39 7.05e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3087591 1.000 rs2854322 chr17:29699416 C/T cg24425628 chr17:29625626 OMG;NF1 0.45 6.65 0.51 8.31e-10 Hip circumference; TGCT cis rs709400 0.663 rs72708893 chr14:103929535 G/A cg12935359 chr14:103987150 CKB -0.37 -5.61 -0.45 1.25e-7 Body mass index; TGCT cis rs6754311 0.509 rs13412397 chr2:136470714 G/A cg07169764 chr2:136633963 MCM6 -0.67 -6.08 -0.48 1.41e-8 Mosquito bite size; TGCT cis rs244731 0.959 rs11740250 chr5:176721272 G/C cg16006841 chr5:176797999 RGS14 0.55 7.12 0.54 7.52e-11 Urate levels in lean individuals; TGCT cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9486719 1.000 rs12212614 chr6:97036466 T/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT trans rs62264129 0.500 rs11923402 chr3:112050148 G/T cg13345683 chr7:154003305 DPP6 0.4 6.64 0.51 8.88e-10 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7772486 0.875 rs9322048 chr6:146400439 A/G cg05347473 chr6:146136440 FBXO30 0.53 5.03 0.41 1.71e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 0.673 rs17015330 chr1:210012795 T/G cg23283495 chr1:209979779 IRF6 0.6 4.5 0.37 1.54e-5 Cleft lip with or without cleft palate; TGCT cis rs4769475 0.629 rs55752743 chr13:26697104 T/C cg19000612 chr13:26506281 ATP8A2 0.33 4.52 0.38 1.44e-5 Response to Homoharringtonine (cytotoxicity); TGCT cis rs7824557 0.527 rs2736298 chr8:11235136 C/G cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.97e-9 Retinal vascular caliber; TGCT cis rs7248779 0.532 rs10153475 chr19:2413961 G/C cg22729335 chr19:2427816 TIMM13 1.13 13.48 0.77 4.71e-26 Cortisol levels (saliva); TGCT cis rs9972944 0.756 rs1421032 chr17:63766368 A/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs6087771 0.781 rs6089067 chr20:30358894 G/C cg13852791 chr20:30311386 BCL2L1 0.8 7.57 0.56 7.42e-12 Subcortical brain region volumes;Putamen volume; TGCT cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg10047753 chr17:41438598 NA 0.96 9.86 0.66 2.71e-17 Menopause (age at onset); TGCT cis rs7772486 0.776 rs4316025 chr6:146238032 C/T cg23711669 chr6:146136114 FBXO30 -0.8 -8.9 -0.62 5.72e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7617480 0.616 rs9873227 chr3:48773108 G/C cg07636037 chr3:49044803 WDR6 0.78 6.39 0.5 3.02e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7103648 1.000 rs10838705 chr11:47424931 G/A cg20307385 chr11:47447363 PSMC3 1.0 12.09 0.74 1.06e-22 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs9611565 0.592 rs4822040 chr22:41963553 C/G cg06481639 chr22:41940642 POLR3H -0.6 -5.14 -0.42 1.03e-6 Vitiligo; TGCT cis rs9611565 0.512 rs2050033 chr22:42159229 G/T cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs7772486 0.875 rs9403768 chr6:146406458 A/C cg23711669 chr6:146136114 FBXO30 0.89 9.73 0.66 5.56e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2070488 0.804 rs13063978 chr3:38476538 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.96 0.58 9.56e-13 Electrocardiographic conduction measures; TGCT cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs2070433 0.752 rs60290737 chr21:47837630 C/A cg12379764 chr21:47803548 PCNT 0.57 4.86 0.4 3.52e-6 Lymphocyte counts; TGCT cis rs4975709 0.610 rs4975705 chr5:1860359 T/C cg07747251 chr5:1868357 NA 0.38 5.43 0.44 2.84e-7 Cardiovascular disease risk factors; TGCT cis rs6089829 0.962 rs7267951 chr20:61665979 A/G cg02380750 chr20:61661411 NA 0.35 6.1 0.48 1.25e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.9e-26 Menopause (age at onset); TGCT cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs4285028 0.580 rs12496036 chr3:121640362 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.61 -5.22 -0.42 7.38e-7 Multiple sclerosis; TGCT cis rs7223966 1.000 rs9899491 chr17:61934384 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9549260 0.599 rs12870023 chr13:41244222 T/A cg21288729 chr13:41239152 FOXO1 1.01 10.56 0.69 5.52e-19 Red blood cell count; TGCT cis rs9473924 0.580 rs60100577 chr6:50816134 C/T cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs35264875 1.000 rs1542334 chr11:68850773 G/C cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs2718812 0.607 rs12497433 chr3:133388584 C/G cg08048268 chr3:133502702 NA -0.38 -4.81 -0.4 4.21e-6 Iron status biomarkers; TGCT cis rs9914544 0.545 rs4924940 chr17:18800092 T/C cg26378065 chr17:18585709 ZNF286B 0.51 4.59 0.38 1.09e-5 Educational attainment (years of education); TGCT cis rs10875746 0.903 rs61918806 chr12:48484433 G/A cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs13242816 1.000 rs35515812 chr7:116156032 C/G cg16553024 chr7:116138462 CAV2 -0.45 -5.27 -0.43 5.81e-7 P wave duration; TGCT cis rs8084125 0.832 rs62105182 chr18:74951407 T/C cg07390210 chr18:74961196 GALR1 0.37 4.51 0.38 1.49e-5 Obesity-related traits; TGCT cis rs76954792 0.826 rs11080166 chr17:30028469 C/A cg18427091 chr17:30115417 NA -0.36 -4.67 -0.39 7.61e-6 Coronary artery disease; TGCT cis rs7432375 0.610 rs28458819 chr3:136522314 A/G cg15507776 chr3:136538369 TMEM22 0.55 5.63 0.45 1.15e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT trans rs56011263 0.687 rs4690293 chr4:706101 A/G cg12575136 chr18:32820987 ZNF397 0.75 8.86 0.62 6.89e-15 White blood cell count; TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg08736216 chr1:53307985 ZYG11A -0.3 -5.99 -0.47 2.09e-8 Monocyte count; TGCT cis rs4819052 0.851 rs13047104 chr21:46673562 T/G cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs56339712 0.802 rs4495524 chr9:92025336 C/G ch.9.1233470F chr9:91626629 NA 0.25 4.78 0.39 4.93e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs9611565 0.592 rs4481089 chr22:41980892 T/C cg06634786 chr22:41940651 POLR3H -0.83 -7.66 -0.57 4.6e-12 Vitiligo; TGCT cis rs6500602 0.592 rs4785966 chr16:4518754 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.39 -5.29 -0.43 5.27e-7 Schizophrenia; TGCT cis rs651907 0.535 rs17412601 chr3:101499275 T/C cg12386194 chr3:101231763 SENP7 0.47 4.7 0.39 6.87e-6 Colorectal cancer; TGCT cis rs7927771 0.800 rs11039200 chr11:47379646 A/C cg21462715 chr11:47870315 NUP160 0.55 4.46 0.37 1.84e-5 Subjective well-being; TGCT cis rs3820068 0.608 rs7514858 chr1:16035246 G/A cg05660106 chr1:15850417 CASP9 0.69 6.45 0.5 2.28e-9 Systolic blood pressure; TGCT cis rs9467603 1.000 rs9461216 chr6:25808743 A/T cg16898833 chr6:26189333 HIST1H4D 1.16 5.5 0.44 2.08e-7 Intelligence (multi-trait analysis); TGCT cis rs875971 0.895 rs12531677 chr7:65769086 G/A cg11764359 chr7:65958608 NA -0.55 -5.0 -0.41 1.94e-6 Aortic root size; TGCT cis rs17376456 0.877 rs10476601 chr5:93402522 G/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs8072100 0.967 rs8078880 chr17:45676526 G/C cg08085267 chr17:45401833 C17orf57 0.43 4.64 0.38 8.8e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs208520 0.690 rs10455194 chr6:66743356 A/G cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg09060608 chr5:178986726 RUFY1 -0.62 -7.62 -0.56 5.63e-12 Lung cancer; TGCT cis rs7547997 0.685 rs1575172 chr1:158345279 A/G cg07950803 chr1:158223934 CD1A 0.32 4.78 0.39 4.95e-6 QRS duration; TGCT cis rs4730250 0.708 rs3801965 chr7:106825628 G/T cg02696742 chr7:106810147 HBP1 -0.7 -6.05 -0.48 1.59e-8 Osteoarthritis; TGCT cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg06640241 chr16:89574553 SPG7 0.66 6.3 0.49 4.82e-9 Multiple myeloma (IgH translocation); TGCT cis rs7044106 0.762 rs10760110 chr9:123412563 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.43 -4.56 -0.38 1.22e-5 Hip circumference adjusted for BMI; TGCT cis rs9399137 0.507 rs4895437 chr6:135317354 G/A cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs6570726 0.791 rs392612 chr6:145881586 C/G cg13319975 chr6:146136371 FBXO30 0.51 4.6 0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4919694 0.572 rs12262258 chr10:104900272 G/A cg04362960 chr10:104952993 NT5C2 0.98 6.88 0.53 2.66e-10 Arsenic metabolism; TGCT cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs17030434 1.000 rs1456391 chr4:154720485 A/G cg14289246 chr4:154710475 SFRP2 -0.91 -7.2 -0.54 5.18e-11 Electrocardiographic conduction measures; TGCT cis rs9677476 0.515 rs13430145 chr2:231931133 T/C cg07929768 chr2:232055508 NA 0.34 5.34 0.43 4.37e-7 Food antigen IgG levels; TGCT cis rs4478037 0.822 rs59834381 chr3:33116313 G/A cg19404215 chr3:33155277 CRTAP 1.25 6.05 0.48 1.59e-8 Major depressive disorder; TGCT cis rs453301 0.624 rs7014430 chr8:8827737 T/G cg11995313 chr8:8860691 ERI1 -0.58 -5.21 -0.42 7.59e-7 Joint mobility (Beighton score); TGCT cis rs7258465 1.000 rs7252707 chr19:18612257 G/A cg22489759 chr19:18572700 ELL 0.21 4.63 0.38 9e-6 Breast cancer; TGCT cis rs7829975 0.840 rs572366 chr8:8578794 A/T cg15556689 chr8:8085844 FLJ10661 0.67 5.67 0.45 9.6e-8 Mood instability; TGCT cis rs7714584 1.000 rs1000113 chr5:150240076 C/T cg22134413 chr5:150180641 NA 1.11 7.97 0.58 8.78e-13 Crohn's disease; TGCT cis rs67311347 1.000 rs2168111 chr3:40395325 T/G cg17264618 chr3:40429014 ENTPD3 0.31 4.65 0.39 8.38e-6 Renal cell carcinoma; TGCT cis rs1691799 0.899 rs1168358 chr12:66748664 A/G cg16791601 chr12:66731901 HELB -0.27 -5.8 -0.46 5.22e-8 White blood cell count (basophil); TGCT cis rs7614311 0.731 rs56263032 chr3:63863022 G/A cg22134162 chr3:63841271 THOC7 -0.4 -5.27 -0.43 5.98e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs16958440 0.867 rs77615793 chr18:44684464 C/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg03452623 chr4:187889614 NA -0.37 -5.65 -0.45 1.06e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs477895 0.713 rs2282490 chr11:63962152 T/C cg04317338 chr11:64019027 PLCB3 0.79 6.5 0.5 1.77e-9 Mean platelet volume; TGCT cis rs28374715 0.662 rs28587487 chr15:41495460 C/T cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.6 -0.72 1.65e-21 Ulcerative colitis; TGCT cis rs8077889 1.000 rs2880329 chr17:41866168 T/A cg26893861 chr17:41843967 DUSP3 1.08 13.1 0.76 3.73e-25 Triglycerides; TGCT cis rs16958440 0.867 rs12326221 chr18:44682893 G/T cg17192377 chr18:44677553 HDHD2 0.64 4.57 0.38 1.15e-5 Sitting height ratio; TGCT cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg11890956 chr21:40555474 PSMG1 -0.75 -6.99 -0.53 1.51e-10 Cognitive function; TGCT cis rs7542091 0.704 rs7537294 chr1:210043777 A/G cg00989853 chr1:209979345 IRF6 0.43 4.58 0.38 1.12e-5 Monobrow; TGCT cis rs4654899 0.965 rs61779124 chr1:21513306 C/T cg01072550 chr1:21505969 NA -0.5 -8.03 -0.59 6.27e-13 Superior frontal gyrus grey matter volume; TGCT cis rs3812831 0.669 rs7327370 chr13:114946858 A/G cg06611532 chr13:114900021 NA 0.34 6.0 0.47 2.02e-8 Schizophrenia; TGCT cis rs4746818 0.901 rs7914719 chr10:70903832 T/C cg04149295 chr10:70884716 VPS26A 0.79 5.39 0.44 3.47e-7 Left atrial antero-posterior diameter; TGCT cis rs875971 0.862 rs10950043 chr7:65988610 T/C cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs7666738 0.753 rs35194639 chr4:99053819 G/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT trans rs1908814 0.516 rs4367597 chr8:11793529 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg11235426 chr6:292522 DUSP22 -0.72 -7.3 -0.55 2.98e-11 Menopause (age at onset); TGCT cis rs1865760 0.827 rs9461227 chr6:25960815 C/T cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs9926296 0.605 rs12448860 chr16:89849629 T/A cg27121462 chr16:89883253 FANCA 0.79 8.46 0.6 6.35e-14 Vitiligo; TGCT cis rs208520 0.565 rs1385222 chr6:66753013 C/T cg07460842 chr6:66804631 NA 1.03 13.89 0.78 4.83e-27 Exhaled nitric oxide output; TGCT cis rs6598955 0.724 rs12726972 chr1:26639634 A/G cg04990556 chr1:26633338 UBXN11 0.9 11.83 0.73 4.36e-22 Obesity-related traits; TGCT cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg16414030 chr3:133502952 NA -0.52 -7.29 -0.55 3.17e-11 Iron status biomarkers; TGCT cis rs3733585 0.673 rs4627861 chr4:9954238 T/G cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs295140 1.000 rs1367857 chr2:201160765 T/C cg04283868 chr2:201171347 SPATS2L 0.63 6.36 0.5 3.56e-9 QT interval; TGCT cis rs9807989 0.501 rs11903946 chr2:103005330 A/G cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs5750830 0.594 rs9611165 chr22:39775250 A/G cg01416388 chr22:39784598 NA -0.59 -5.8 -0.46 5.09e-8 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.581 rs72645879 chr1:15928199 A/G cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg05985448 chr10:134359359 INPP5A 0.24 5.13 0.42 1.1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11874712 1.000 rs8089150 chr18:43674300 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg06942814 chr7:27170819 HOXA4 -0.39 -4.46 -0.37 1.8e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs3902035 0.964 rs62423995 chr6:119011836 G/A cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs2153904 0.793 rs12118655 chr1:205663478 A/G cg23034840 chr1:205782522 SLC41A1 -0.72 -4.76 -0.39 5.23e-6 Prostate-specific antigen levels; TGCT cis rs17001868 0.568 rs9611318 chr22:40739414 C/G cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs6570726 0.791 rs436498 chr6:145876347 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs6839277 chr4:99015563 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs7618501 0.519 rs3774749 chr3:50207227 C/T cg21659725 chr3:3221576 CRBN -0.7 -7.99 -0.58 8.03e-13 Intelligence (multi-trait analysis); TGCT cis rs7178572 0.633 rs4886876 chr15:77838491 C/T cg22256960 chr15:77711686 NA -0.78 -7.45 -0.56 1.42e-11 Type 2 diabetes; TGCT cis rs9303401 0.614 rs7215900 chr17:56654850 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.61 5.86 0.47 3.87e-8 Cognitive test performance; TGCT cis rs9787249 0.957 rs2274949 chr1:40221067 G/A cg24920358 chr1:40204285 PPIE 0.57 10.63 0.69 3.68e-19 Blood protein levels; TGCT cis rs875971 0.862 rs1695820 chr7:65844563 G/A cg11764359 chr7:65958608 NA 0.57 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs2456568 0.867 rs1395384 chr11:93663250 C/T cg26875233 chr11:93583750 C11orf90 0.46 5.75 0.46 6.47e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs832540 0.656 rs702689 chr5:56177443 G/A cg12311346 chr5:56204834 C5orf35 -0.5 -5.11 -0.42 1.2e-6 Coronary artery disease; TGCT cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg22105103 chr4:187893119 NA 0.35 4.89 0.4 3.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7659604 0.689 rs59131059 chr4:122666357 C/T cg19748678 chr4:122722346 EXOSC9 0.55 5.31 0.43 4.92e-7 Type 2 diabetes; TGCT trans rs1814175 0.817 rs1851858 chr11:49855638 G/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs9443645 0.901 rs10455356 chr6:79664748 T/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg17971929 chr21:40555470 PSMG1 0.98 9.51 0.65 1.95e-16 Cognitive function; TGCT cis rs9419702 0.639 rs4367873 chr10:133533485 C/T cg04492858 chr10:133558786 NA 0.55 5.71 0.46 7.96e-8 Survival in rectal cancer; TGCT cis rs9993613 0.875 rs12639746 chr4:73513026 C/T cg15102770 chr4:73434591 ADAMTS3 0.5 4.6 0.38 1.03e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg13732083 chr21:47605072 C21orf56 0.35 4.75 0.39 5.51e-6 Testicular germ cell tumor; TGCT cis rs7809950 0.678 rs2301801 chr7:106870746 T/C cg23024343 chr7:107201750 COG5 -0.44 -6.17 -0.48 8.73e-9 Coronary artery disease; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg23156509 chr2:114033830 PAX8;LOC440839 -0.32 -4.93 -0.4 2.58e-6 Lymphocyte counts; TGCT cis rs2404602 0.583 rs12913096 chr15:76551852 C/T cg26408565 chr15:76604113 ETFA -0.45 -6.36 -0.5 3.6e-9 Blood metabolite levels; TGCT cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.86 5.42 0.44 3.05e-7 Alzheimer's disease; TGCT cis rs7020830 0.928 rs11544336 chr9:37089150 A/G cg14294708 chr9:37120828 ZCCHC7 1.28 20.28 0.88 3.46e-41 Schizophrenia; TGCT cis rs2277425 0.755 rs2277424 chr13:111522420 A/G cg13698168 chr13:111522651 C13orf29 -0.33 -4.62 -0.38 9.53e-6 Sitting height ratio; TGCT cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs10256972 0.524 rs6945202 chr7:1116558 T/C cg18765753 chr7:1198926 ZFAND2A -0.44 -4.57 -0.38 1.18e-5 Longevity;Endometriosis; TGCT cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg03806693 chr22:41940476 POLR3H -1.11 -11.64 -0.72 1.26e-21 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1153858 1.000 rs4395020 chr15:45652889 A/C cg26924012 chr15:45694286 SPATA5L1 1.1 14.88 0.8 2.26e-29 Homoarginine levels; TGCT cis rs8141529 0.748 rs5762882 chr22:29290680 C/A cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs2456568 0.802 rs1395387 chr11:93639307 A/T cg26875233 chr11:93583750 C11orf90 -0.47 -6.1 -0.48 1.27e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6546537 1.000 rs6546537 chr2:69839633 T/C cg10773587 chr2:69614142 GFPT1 -0.62 -5.21 -0.42 7.66e-7 Serum thyroid-stimulating hormone levels; TGCT cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg19774624 chr17:42201019 HDAC5 -0.84 -10.39 -0.68 1.44e-18 Total body bone mineral density; TGCT cis rs17102423 0.755 rs4902358 chr14:65542477 A/G cg11161011 chr14:65562177 MAX -0.55 -7.71 -0.57 3.47e-12 Obesity-related traits; TGCT cis rs933688 1.000 rs10073935 chr5:90742188 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.43 0.6 7.52e-14 Smoking behavior; TGCT cis rs6938 0.618 rs11857695 chr15:75165751 G/T cg10253484 chr15:75165896 SCAMP2 -0.53 -4.88 -0.4 3.15e-6 Breast cancer; TGCT cis rs2204008 0.782 rs117824012 chr12:38215517 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs9296092 0.538 rs9461875 chr6:33516644 C/T cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.08e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6087771 0.662 rs6058298 chr20:30247916 C/T cg13852791 chr20:30311386 BCL2L1 0.8 7.16 0.54 6.39e-11 Subcortical brain region volumes;Putamen volume; TGCT cis rs4711350 0.862 rs570749 chr6:33710229 C/T cg18005901 chr6:33739558 LEMD2 0.57 5.9 0.47 3.23e-8 Schizophrenia; TGCT cis rs7267979 1.000 rs4813563 chr20:25365340 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6732795 0.854 rs6546486 chr2:69413892 A/T cg10773587 chr2:69614142 GFPT1 -0.52 -4.82 -0.4 4.05e-6 Intraocular pressure; TGCT cis rs11105298 0.786 rs10777186 chr12:89921277 G/A cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs41271951 0.512 rs116666233 chr1:151056058 C/T cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs9549367 0.789 rs12584813 chr13:113895443 C/G cg18105134 chr13:113819100 PROZ -0.37 -5.0 -0.41 1.89e-6 Platelet distribution width; TGCT cis rs9818758 0.607 rs67831908 chr3:49313513 T/G cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs854572 0.600 rs705382 chr7:94955221 C/G cg07404485 chr7:94953653 PON1 -0.27 -4.78 -0.39 4.92e-6 Paraoxonase activity; TGCT cis rs909674 0.818 rs5757680 chr22:39844793 C/T cg24399712 chr22:39784796 NA 1.01 10.46 0.68 9.83e-19 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT trans rs1814175 0.676 rs1851859 chr11:49860405 A/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs950027 0.620 rs1145076 chr15:45684508 G/T cg26924012 chr15:45694286 SPATA5L1 0.78 8.83 0.62 8.22e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg08736216 chr1:53307985 ZYG11A 0.29 5.89 0.47 3.41e-8 Monocyte count; TGCT cis rs10197940 0.686 rs12616688 chr2:152242099 C/G cg19508488 chr2:152266495 RIF1 0.73 6.58 0.51 1.2e-9 Lung cancer; TGCT cis rs4936891 0.601 rs7929503 chr11:123916160 A/G cg22125253 chr11:123886957 OR10G4 0.21 4.82 0.4 4.13e-6 Male fertility; TGCT cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs35934224 0.843 rs1139795 chr22:19867771 C/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.37 -0.43 3.79e-7 Glaucoma (primary open-angle); TGCT cis rs9788682 0.747 rs8042374 chr15:78908032 A/G cg24631222 chr15:78858424 CHRNA5 0.78 5.71 0.46 8.03e-8 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs4253772 0.591 rs6008545 chr22:46686375 C/T cg26492175 chr22:47022658 GRAMD4 0.2 4.57 0.38 1.15e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs35306767 0.903 rs34847097 chr10:902252 A/T cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs2031577 1.000 rs4881271 chr10:4047125 G/T cg19231290 chr10:3827321 KLF6 0.41 4.47 0.37 1.71e-5 Longevity; TGCT cis rs6089584 1.000 rs6089581 chr20:60562394 G/A cg06108461 chr20:60628389 TAF4 -0.57 -8.01 -0.58 7.25e-13 Body mass index; TGCT cis rs265548 0.586 rs265542 chr19:17904388 T/G cg04517722 chr19:17905589 B3GNT3 0.46 5.96 0.47 2.42e-8 Tumor biomarkers; TGCT cis rs597539 0.617 rs672853 chr11:68636362 G/A cg06112835 chr11:68658793 MRPL21 0.47 8.18 0.59 2.86e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs5769765 0.865 rs3788730 chr22:50244695 C/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.35 -5.41 -0.44 3.05e-7 Schizophrenia; TGCT cis rs9467711 0.606 rs34104395 chr6:26478252 C/T cg16898833 chr6:26189333 HIST1H4D 1.13 5.05 0.41 1.56e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6840360 0.571 rs6811676 chr4:152562726 T/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs3749237 1.000 rs2307021 chr3:49765483 C/G cg07636037 chr3:49044803 WDR6 0.61 5.32 0.43 4.68e-7 Resting heart rate; TGCT cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs6460942 0.915 rs1595802 chr7:12439672 C/T cg06484146 chr7:12443880 VWDE -0.57 -5.46 -0.44 2.47e-7 Coronary artery disease; TGCT cis rs611744 0.967 rs612265 chr8:109188650 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs853679 0.517 rs9368553 chr6:28082265 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs7829975 0.617 rs4841071 chr8:8791144 G/T cg15556689 chr8:8085844 FLJ10661 0.63 5.94 0.47 2.69e-8 Mood instability; TGCT cis rs240764 0.658 rs7740783 chr6:101263516 C/T cg21058520 chr6:100914733 NA -0.35 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs11971779 0.793 rs4732366 chr7:139027845 G/C cg07862535 chr7:139043722 LUC7L2 0.75 6.01 0.47 1.95e-8 Diisocyanate-induced asthma; TGCT trans rs208520 0.779 rs208446 chr6:66903515 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.93 -9.78 -0.66 4.3e-17 Exhaled nitric oxide output; TGCT cis rs7666738 0.830 rs6819047 chr4:98866902 G/A cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17534004 1.000 rs17534004 chr13:31469665 C/T cg13251181 chr13:31481184 C13orf33 0.37 4.6 0.38 1.04e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs11148252 0.538 rs2408611 chr13:52709742 C/T cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.84e-8 Lewy body disease; TGCT cis rs1949733 1.000 rs6837429 chr4:8502374 A/G cg13073564 chr4:8508604 NA -0.47 -5.05 -0.41 1.55e-6 Response to antineoplastic agents; TGCT cis rs13064447 0.967 rs113886525 chr3:12762356 A/G cg20675869 chr3:12750130 NA -0.18 -4.6 -0.38 1.01e-5 Major depression and alcohol dependence; TGCT cis rs473651 0.935 rs540636 chr2:239358341 T/C cg21699342 chr2:239360505 ASB1 0.17 4.65 0.39 8.49e-6 Multiple system atrophy; TGCT cis rs4148883 0.651 rs4147547 chr4:100127311 G/T cg12011299 chr4:100065546 ADH4 0.36 5.39 0.44 3.38e-7 Alcohol dependence; TGCT cis rs12579753 0.789 rs1343933 chr12:82123301 A/C cg07988820 chr12:82153109 PPFIA2 -0.67 -7.13 -0.54 7.42e-11 Resting heart rate; TGCT cis rs7949030 0.504 rs2516633 chr11:62371773 A/C cg22862634 chr11:62369728 EML3;MTA2 -0.59 -6.11 -0.48 1.17e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9914544 0.545 rs8078993 chr17:18797126 A/G cg26378065 chr17:18585709 ZNF286B 0.51 4.59 0.38 1.09e-5 Educational attainment (years of education); TGCT cis rs2721195 0.967 rs1985022 chr8:145684031 C/T cg13257436 chr8:145726034 PPP1R16A -0.34 -5.16 -0.42 9.7e-7 Age at first birth; TGCT cis rs7267979 0.844 rs6083851 chr20:25401235 G/A cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10114408 0.959 rs10761298 chr9:96648815 G/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7429990 0.965 rs5016900 chr3:47822877 G/C cg11946769 chr3:48343235 NME6 0.59 4.45 0.37 1.87e-5 Educational attainment (years of education); TGCT cis rs2932538 0.922 rs6673930 chr1:113104887 A/G cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs4722166 0.508 rs1474347 chr7:22768124 A/C cg26061582 chr7:22766209 IL6 -0.52 -6.5 -0.5 1.77e-9 Lung cancer; TGCT cis rs208520 1.000 rs12189683 chr6:66977716 A/C cg07460842 chr6:66804631 NA -0.78 -6.82 -0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs10744422 0.764 rs11060152 chr12:123298932 G/A cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs9527 0.544 rs1572578 chr10:104822431 C/G cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT cis rs6570726 0.935 rs447247 chr6:145812678 G/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.16e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6545883 0.826 rs777593 chr2:61419103 C/A cg15711740 chr2:61764176 XPO1 -0.58 -5.09 -0.42 1.3e-6 Tuberculosis; TGCT cis rs7914558 1.000 rs11191577 chr10:104902165 A/G cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.66e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs71435601 0.574 rs522963 chr2:21386957 T/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs9653442 0.564 rs7593261 chr2:100789907 A/G cg22139774 chr2:100720529 AFF3 -0.34 -5.21 -0.42 7.55e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs734999 0.967 rs10752745 chr1:2507938 A/G cg18854424 chr1:2615690 NA 0.44 5.37 0.43 3.77e-7 Ulcerative colitis; TGCT cis rs7772486 0.790 rs2265472 chr6:146220758 G/C cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.89e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs1814175 0.817 rs11493756 chr11:50017885 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs634534 0.622 rs1308733 chr11:65720841 T/C cg04055107 chr11:65626734 MUS81;CFL1 -0.47 -4.68 -0.39 7.38e-6 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7829975 0.714 rs11777085 chr8:8672429 G/C cg08975724 chr8:8085496 FLJ10661 0.5 4.52 0.38 1.45e-5 Mood instability; TGCT trans rs941408 1.000 rs1736183 chr19:2809672 A/G cg19676328 chr12:49525230 TUBA1B -0.72 -7.19 -0.54 5.31e-11 Total cholesterol levels; TGCT cis rs988712 0.705 rs11030099 chr11:27677583 C/A cg10635145 chr11:27742435 BDNF -0.4 -5.55 -0.45 1.65e-7 Obesity; TGCT cis rs2013441 0.965 rs6587063 chr17:20193940 T/C cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs589448 0.872 rs315111 chr12:69784695 G/A cg14784868 chr12:69753453 YEATS4 0.9 10.6 0.69 4.47e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs8180040 0.764 rs6794193 chr3:47114904 T/C cg27129171 chr3:47204927 SETD2 0.74 9.79 0.66 4.15e-17 Colorectal cancer; TGCT cis rs9733 0.650 rs12125672 chr1:150554470 A/T cg13175981 chr1:150552382 MCL1 0.51 5.66 0.45 9.73e-8 Tonsillectomy; TGCT trans rs7698623 0.850 rs1477604 chr4:88771060 C/T cg01186725 chr1:53905612 FLJ40434 -0.47 -6.65 -0.51 8.29e-10 Cardiovascular disease risk factors; TGCT cis rs7647973 0.626 rs1078341 chr3:49685592 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs600231 0.706 rs4244811 chr11:65320780 G/A cg21890820 chr11:65308645 LTBP3 -0.36 -4.64 -0.38 8.63e-6 Bone mineral density; TGCT cis rs854765 0.647 rs854817 chr17:18021882 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.51 0.56 1.01e-11 Total body bone mineral density; TGCT cis rs2235642 0.826 rs8048410 chr16:1614097 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.32 -5.2 -0.42 8.15e-7 Coronary artery disease; TGCT cis rs941873 0.868 rs2233718 chr10:81108956 A/G cg09469691 chr10:81107165 PPIF 0.56 5.43 0.44 2.9e-7 Height; TGCT cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg09436375 chr6:42928200 GNMT -0.41 -5.39 -0.44 3.46e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg21433313 chr16:3507492 NAT15 0.38 5.06 0.41 1.5e-6 Tuberculosis; TGCT cis rs71435601 0.699 rs515135 chr2:21286057 T/C cg16306978 chr2:21266953 APOB 0.59 4.63 0.38 9.24e-6 Cholesterol, total; TGCT cis rs601339 1.000 rs2454722 chr12:123171218 A/G cg11919336 chr12:123188078 GPR109A 0.66 7.7 0.57 3.69e-12 Adiponectin levels; TGCT cis rs7119038 0.818 rs6589684 chr11:118610957 A/G cg19308663 chr11:118741387 NA -0.23 -4.78 -0.39 4.83e-6 Sjögren's syndrome; TGCT cis rs5769707 0.935 rs739239 chr22:50050468 G/A cg10356904 chr22:49881777 NA -0.23 -4.66 -0.39 7.88e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg09060608 chr5:178986726 RUFY1 0.5 5.64 0.45 1.12e-7 Lung cancer; TGCT cis rs4819052 0.851 rs1056100 chr21:46678711 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 6.87 0.53 2.77e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg14820908 chr5:178986412 RUFY1 0.6 6.71 0.52 6.31e-10 Lung cancer; TGCT cis rs8072100 0.905 rs11651766 chr17:45574931 G/T cg08085267 chr17:45401833 C17orf57 -0.44 -4.72 -0.39 6.17e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1153858 1.000 rs12593370 chr15:45617417 C/T cg26924012 chr15:45694286 SPATA5L1 1.05 13.95 0.78 3.56e-27 Homoarginine levels; TGCT cis rs9611565 0.879 rs5758307 chr22:41750219 A/G cg13695892 chr22:41940480 POLR3H -0.84 -8.22 -0.59 2.28e-13 Vitiligo; TGCT cis rs9611519 0.603 rs9607764 chr22:41411804 G/C cg06634786 chr22:41940651 POLR3H -0.49 -4.53 -0.38 1.38e-5 Neuroticism; TGCT cis rs17376456 0.877 rs67066109 chr5:93494101 G/C cg21475434 chr5:93447410 FAM172A 0.63 4.63 0.38 8.98e-6 Diabetic retinopathy; TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.54 4.78 0.39 4.86e-6 Prudent dietary pattern; TGCT cis rs17152411 0.947 rs733400 chr10:126594340 G/A cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs11190604 1.000 rs7100386 chr10:102301417 C/T cg16342193 chr10:102329863 NA -0.4 -4.97 -0.41 2.14e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs909674 0.734 rs5757675 chr22:39838892 G/T cg24399712 chr22:39784796 NA -1.05 -11.41 -0.72 4.79e-21 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1670533 0.932 rs3796620 chr4:1095079 A/G cg20887711 chr4:1340912 KIAA1530 -0.68 -5.47 -0.44 2.33e-7 Recombination rate (females); TGCT cis rs9926296 0.609 rs4785714 chr16:89798404 G/T cg08627397 chr16:89984028 MC1R 0.29 4.5 0.37 1.52e-5 Vitiligo; TGCT cis rs986417 1.000 rs1254298 chr14:60883842 C/T cg27398547 chr14:60952738 C14orf39 -1.58 -8.33 -0.6 1.24e-13 Gut microbiota (bacterial taxa); TGCT cis rs858239 0.863 rs274058 chr7:23391509 C/G cg05602783 chr7:23145260 KLHL7 -0.56 -4.58 -0.38 1.13e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs8014252 0.803 rs12587714 chr14:71004376 G/C cg11204974 chr14:71022665 NA -0.53 -4.46 -0.37 1.79e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs4803468 1.000 rs284658 chr19:41929988 G/A cg09537434 chr19:41945824 ATP5SL -0.93 -10.96 -0.7 5.8e-20 Height; TGCT cis rs4700695 0.841 rs706679 chr5:65317181 A/G cg21114390 chr5:65439923 SFRS12 -0.59 -4.44 -0.37 1.99e-5 Facial morphology (factor 19); TGCT cis rs9916302 0.706 rs7503081 chr17:37482673 A/G cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs2067615 0.579 rs10861663 chr12:107183589 G/A cg15890332 chr12:107067104 RFX4 0.3 6.06 0.48 1.54e-8 Heart rate; TGCT cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg15659132 chr6:26577336 NA 0.85 10.93 0.7 7e-20 Intelligence (multi-trait analysis); TGCT cis rs7000551 0.689 rs2122878 chr8:22311916 T/C cg12081754 chr8:22256438 SLC39A14 0.31 5.17 0.42 8.96e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg02353165 chr6:42928485 GNMT 0.94 9.24 0.64 8.85e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7824557 0.603 rs2249804 chr8:11215617 C/G cg21775007 chr8:11205619 TDH 0.63 5.85 0.47 4.03e-8 Retinal vascular caliber; TGCT cis rs10479542 0.683 rs7380706 chr5:178961872 C/T cg21226059 chr5:178986404 RUFY1 0.41 4.49 0.37 1.61e-5 Lung cancer; TGCT cis rs10782582 0.609 rs1630587 chr1:76399787 T/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.46 0.37 1.83e-5 Daytime sleep phenotypes; TGCT cis rs514406 0.763 rs7535088 chr1:53215042 A/G cg25767906 chr1:53392781 SCP2 0.48 5.36 0.43 3.95e-7 Monocyte count; TGCT cis rs3617 0.573 rs12492391 chr3:52912296 C/A cg10802521 chr3:52805072 NEK4 -0.54 -5.99 -0.47 2.09e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7267979 1.000 rs884613 chr20:25288505 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs992157 0.835 rs10932769 chr2:219147245 T/G cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT trans rs7726839 0.540 rs56325086 chr5:640728 G/A cg11887960 chr12:57824829 NA 1.09 8.89 0.62 6.07e-15 Obesity-related traits; TGCT cis rs7726839 0.507 rs111707179 chr5:593308 T/A cg20362242 chr5:692897 TPPP 0.53 4.62 0.38 9.42e-6 Obesity-related traits; TGCT cis rs1577917 0.545 rs1335443 chr6:86478737 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.57 -4.66 -0.39 7.89e-6 Response to antipsychotic treatment; TGCT cis rs1375194 0.606 rs17657783 chr2:33814590 A/G cg04131969 chr2:33951647 MYADML -0.58 -5.07 -0.41 1.41e-6 Response to antidepressants in depression; TGCT cis rs10089 0.953 rs6879970 chr5:127387178 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs2204008 0.811 rs2139752 chr12:38370398 C/T cg13010199 chr12:38710504 ALG10B 0.6 4.68 0.39 7.36e-6 Bladder cancer; TGCT cis rs1372520 0.684 rs2583978 chr4:90750326 A/C cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs9640161 0.750 rs1983440 chr7:150023941 G/C cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 8.94e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs7027203 0.663 rs4428726 chr9:96623559 T/G cg13679303 chr9:96623674 NA -0.69 -11.4 -0.72 4.94e-21 DNA methylation (variation); TGCT cis rs798766 0.779 rs3134866 chr4:1723265 A/G cg05874882 chr4:1763078 NA -0.36 -4.87 -0.4 3.27e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs7591446 0.517 rs7596942 chr2:45839700 G/T cg15146906 chr2:45838581 SRBD1 0.7 5.2 0.42 7.98e-7 Squamous cell lung carcinoma; TGCT cis rs617219 0.684 rs2896766 chr5:78586493 A/G cg09550809 chr5:78407562 BHMT -0.37 -5.25 -0.43 6.49e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9796 0.870 rs4244584 chr15:41259523 A/G cg18705301 chr15:41695430 NDUFAF1 0.4 5.24 0.43 6.58e-7 Menopause (age at onset); TGCT cis rs12653946 0.846 rs10866528 chr5:1891821 A/G cg22472608 chr5:1891194 NA -0.67 -8.59 -0.61 3.06e-14 Prostate cancer; TGCT cis rs9443645 0.901 rs1354831 chr6:79613576 T/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs6586111 0.967 rs6586106 chr10:82372300 A/C cg03086067 chr10:82368399 SH2D4B -0.24 -4.72 -0.39 6.14e-6 Capecitabine sensitivity; TGCT cis rs9549260 0.564 rs9549279 chr13:41315582 C/G cg21288729 chr13:41239152 FOXO1 -0.94 -9.29 -0.64 6.57e-16 Red blood cell count; TGCT cis rs7666738 0.830 rs13125930 chr4:98654695 G/A cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.41e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7829975 0.777 rs560544 chr8:8637429 G/A cg15556689 chr8:8085844 FLJ10661 -0.69 -6.15 -0.48 9.85e-9 Mood instability; TGCT cis rs7647973 1.000 rs3870339 chr3:49536863 T/A cg07690219 chr3:49449608 TCTA;RHOA -0.53 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs7772486 0.686 rs4896833 chr6:145965673 T/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2050392 0.590 rs303433 chr10:30714963 A/T cg13289132 chr10:30722225 MAP3K8 -0.45 -5.48 -0.44 2.25e-7 Inflammatory bowel disease; TGCT cis rs801193 0.636 rs2659895 chr7:66196471 C/A cg11764359 chr7:65958608 NA 0.59 5.09 0.42 1.28e-6 Aortic root size; TGCT cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs13256369 0.851 rs13271698 chr8:8567539 C/A cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs28735056 0.620 rs12456484 chr18:77677315 C/G cg20368463 chr18:77673604 PQLC1 0.48 5.73 0.46 7.27e-8 Schizophrenia; TGCT trans rs4332037 1.000 rs6947019 chr7:1950337 G/A cg25206134 chr2:45395956 NA 1.11 9.39 0.64 3.79e-16 Bipolar disorder; TGCT cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs12791968 0.765 rs12794751 chr11:44998769 C/G cg11846598 chr11:44996168 LOC221122 -0.31 -4.8 -0.4 4.4e-6 Inhibitory control; TGCT cis rs1008375 0.966 rs28750296 chr4:17685826 A/T cg10189774 chr4:17578691 LAP3 0.52 4.74 0.39 5.82e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7618501 0.633 rs6792892 chr3:49995518 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.92 0.67 1.95e-17 Intelligence (multi-trait analysis); TGCT cis rs6938 0.534 rs12907898 chr15:75207872 C/T cg10253484 chr15:75165896 SCAMP2 -0.57 -5.28 -0.43 5.69e-7 Breast cancer; TGCT cis rs13191362 1.000 rs35754151 chr6:163074867 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.89 6.36 0.5 3.55e-9 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9926296 0.568 rs417323 chr16:89746277 T/G cg04287289 chr16:89883240 FANCA -0.54 -5.09 -0.42 1.32e-6 Vitiligo; TGCT cis rs17376456 0.825 rs17372057 chr5:93071916 C/A cg21475434 chr5:93447410 FAM172A 0.64 5.05 0.41 1.52e-6 Diabetic retinopathy; TGCT cis rs79349575 0.749 rs58838744 chr17:46998902 A/G cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs1371867 0.846 rs1788167 chr8:101319996 C/T cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs6892003 0.857 rs58936790 chr5:174179520 T/C cg06056415 chr5:174162510 NA 0.44 4.6 0.38 1.04e-5 Clopidogrel active metabolite levels; TGCT trans rs7618501 1.000 rs2271960 chr3:49878078 A/G cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs10876993 0.855 rs1678520 chr12:58049319 C/G cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7943191 0.810 rs7942991 chr11:62337203 A/G cg13298116 chr11:62369859 EML3;MTA2 -0.57 -6.84 -0.52 3.19e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg05985448 chr10:134359359 INPP5A 0.23 5.11 0.42 1.2e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17601876 0.814 rs8029537 chr15:51557698 A/G cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs4951018 0.853 rs1573104 chr1:205636907 A/C cg14893161 chr1:205819251 PM20D1 -0.36 -4.76 -0.39 5.39e-6 Prostate-specific antigen levels; TGCT cis rs60154123 0.505 rs2206043 chr1:210042983 G/A cg21951975 chr1:209979733 IRF6 0.69 5.18 0.42 8.74e-7 Coronary artery disease; TGCT cis rs713587 0.571 rs2917916 chr2:25316336 A/C cg01884057 chr2:25150051 NA -0.26 -4.88 -0.4 3.16e-6 Body mass index in non-asthmatics; TGCT cis rs7937612 1.000 rs7117063 chr11:120238824 T/C cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.7 -0.39 6.76e-6 Intraocular pressure; TGCT cis rs17739794 0.557 rs7823711 chr8:814529 A/G cg01971667 chr8:817044 NA -0.29 -4.44 -0.37 1.97e-5 Clozapine-induced cytotoxicity; TGCT cis rs17741873 0.836 rs12221230 chr10:75604972 T/C cg07699608 chr10:75541558 CHCHD1 0.71 4.81 0.4 4.26e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs2964802 0.505 rs7729989 chr5:10822246 A/G cg14521931 chr5:10832172 NA -0.28 -4.74 -0.39 5.78e-6 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs12049351 0.774 rs3767327 chr1:229659310 C/G cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7192750 0.539 rs12599192 chr16:71979097 G/A cg06353428 chr16:71660113 MARVELD3 0.75 6.74 0.52 5.43e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs6964587 1.000 rs10488510 chr7:91660225 G/T cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs875971 0.964 rs6945019 chr7:65922458 C/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs35306767 0.903 rs12764024 chr10:922861 A/G cg20503657 chr10:835505 NA 0.73 9.79 0.66 4.03e-17 Eosinophil percentage of granulocytes; TGCT cis rs2050392 1.000 rs2250714 chr10:30697396 G/C cg18806716 chr10:30721971 MAP3K8 -0.46 -5.35 -0.43 4.06e-7 Inflammatory bowel disease; TGCT cis rs7914558 0.966 rs10786745 chr10:104956827 A/G cg05855489 chr10:104503620 C10orf26 0.52 4.58 0.38 1.1e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1903068 0.819 rs17711320 chr4:56000053 A/C cg16572876 chr4:56024045 NA 0.43 4.94 0.41 2.43e-6 Endometriosis; TGCT cis rs4523957 0.651 rs7223390 chr17:2085653 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg10560079 chr2:191398806 TMEM194B 0.37 5.35 0.43 4.14e-7 Pulse pressure; TGCT cis rs8070740 0.836 rs4444392 chr17:5324588 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs9291683 0.588 rs17247314 chr4:10004743 C/G cg00071950 chr4:10020882 SLC2A9 0.67 9.01 0.63 3.02e-15 Bone mineral density; TGCT cis rs2073300 1.000 rs6114098 chr20:23444276 G/A cg09953122 chr20:23471693 CST8 -0.61 -4.45 -0.37 1.9e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs11148252 0.574 rs9536247 chr13:53279542 T/C cg00495681 chr13:53174319 NA 0.71 7.41 0.55 1.69e-11 Lewy body disease; TGCT cis rs9549260 0.755 rs7985364 chr13:41179580 C/G cg21288729 chr13:41239152 FOXO1 1.0 10.06 0.67 9.29e-18 Red blood cell count; TGCT cis rs3820068 0.705 rs11577225 chr1:15864242 T/C cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs734999 0.588 rs10910099 chr1:2533552 G/T cg18854424 chr1:2615690 NA -0.46 -5.33 -0.43 4.38e-7 Ulcerative colitis; TGCT cis rs1218582 0.740 rs1977879 chr1:154879743 G/A cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs2153535 0.580 rs9406161 chr6:8466144 G/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1062177 0.756 rs2915817 chr5:151115517 T/C cg00977110 chr5:151150581 G3BP1 -0.4 -4.6 -0.38 1.03e-5 Preschool internalizing problems; TGCT cis rs2303745 0.544 rs6512181 chr19:17399213 T/G cg02221750 chr19:17393354 ANKLE1 -0.46 -5.87 -0.47 3.73e-8 Systemic lupus erythematosus; TGCT cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg23982607 chr1:1823379 GNB1 -0.55 -8.35 -0.6 1.15e-13 Body mass index; TGCT cis rs881375 0.967 rs1930781 chr9:123687834 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.99 0.41 2.03e-6 Rheumatoid arthritis; TGCT cis rs7833790 0.724 rs1054078 chr8:82712153 A/G cg06027949 chr8:82754900 SNX16 -0.65 -5.03 -0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs2777491 1.000 rs2777491 chr15:41735710 T/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.01 -0.7 4.47e-20 Ulcerative colitis; TGCT cis rs6570726 0.689 rs411785 chr6:145888398 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6669919 0.510 rs4951758 chr1:211690631 A/G cg26515805 chr1:211431828 RCOR3 -0.43 -4.63 -0.38 8.96e-6 Intelligence (multi-trait analysis); TGCT cis rs11677370 0.561 rs4849990 chr2:3819558 A/G cg17052675 chr2:3827356 NA -0.45 -7.33 -0.55 2.63e-11 Type 2 diabetes; TGCT cis rs9372253 1.000 rs9372253 chr6:110716136 C/T cg19196401 chr6:110721138 DDO -0.5 -7.33 -0.55 2.59e-11 Platelet distribution width; TGCT cis rs514406 0.505 rs374662 chr1:53164549 C/A cg16325326 chr1:53192061 ZYG11B 0.85 11.53 0.72 2.38e-21 Monocyte count; TGCT cis rs1008375 1.000 rs11947857 chr4:17691047 T/C cg10189774 chr4:17578691 LAP3 -0.58 -4.94 -0.41 2.52e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7772486 0.692 rs1577916 chr6:146069789 G/A cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4888262 0.526 rs12921903 chr16:74625575 C/T cg01733217 chr16:74700730 RFWD3 0.74 7.48 0.56 1.16e-11 Testicular germ cell tumor; TGCT cis rs1577917 0.958 rs12209668 chr6:86566517 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs589448 0.538 rs683790 chr12:69751434 T/G cg20891283 chr12:69753455 YEATS4 0.66 5.73 0.46 7.22e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs1046896 0.594 rs4075209 chr17:80800027 G/T cg03160526 chr17:80928410 B3GNTL1 0.33 4.61 0.38 9.86e-6 Glycated hemoglobin levels; TGCT cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs2811893 1.000 rs232861 chr1:59120399 T/G cg26196860 chr1:59745563 NA 0.24 4.44 0.37 1.96e-5 Diabetic retinopathy; TGCT cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg17554472 chr22:41940697 POLR3H -0.52 -5.37 -0.43 3.79e-7 Vitiligo; TGCT cis rs3617 0.652 rs7630552 chr3:52891570 G/C cg11645453 chr3:52864694 ITIH4 -0.29 -5.68 -0.45 9.09e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2204008 0.806 rs11520229 chr12:38246448 C/A cg26384229 chr12:38710491 ALG10B 0.86 7.42 0.55 1.6e-11 Bladder cancer; TGCT cis rs12220898 0.833 rs3996895 chr10:50484365 G/A cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs739496 0.947 rs2301621 chr12:111895272 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs9534288 0.762 rs1571053 chr13:46554854 G/A cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs782590 0.935 rs10460508 chr2:55882565 A/C cg18811423 chr2:55921094 PNPT1 0.63 6.49 0.5 1.84e-9 Metabolic syndrome; TGCT cis rs9911578 0.741 rs2611776 chr17:56819636 G/T cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.841 rs114465037 chr4:119778165 A/G cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs4319547 0.656 rs2173582 chr12:122824694 A/G cg08088222 chr12:122070432 ORAI1 0.26 4.64 0.38 8.63e-6 Body mass index; TGCT cis rs3096299 0.685 rs8050512 chr16:89552320 C/G cg02187348 chr16:89574699 SPG7 0.62 6.66 0.51 7.77e-10 Multiple myeloma (IgH translocation); TGCT cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.97 0.47 2.36e-8 Bipolar disorder; TGCT cis rs1357245 0.503 rs9816609 chr3:27100459 A/G cg02860705 chr3:27208620 NA 0.32 5.09 0.42 1.3e-6 Breast cancer; TGCT cis rs4919694 1.000 rs3740394 chr10:104634474 A/G cg04362960 chr10:104952993 NT5C2 1.03 6.98 0.53 1.61e-10 Arsenic metabolism; TGCT cis rs6088580 0.634 rs945673 chr20:32964265 C/A cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.98e-7 Glomerular filtration rate (creatinine); TGCT trans rs877282 0.853 rs7092652 chr10:756109 G/A cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs875971 0.862 rs778734 chr7:65814849 C/G cg11764359 chr7:65958608 NA 0.58 5.27 0.43 5.77e-7 Aortic root size; TGCT cis rs4819052 1.000 rs9984901 chr21:46663952 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.86 7.29 0.55 3.13e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs832540 0.931 rs331499 chr5:56210923 C/T cg17801930 chr5:56009405 NA -0.21 -4.43 -0.37 2.01e-5 Coronary artery disease; TGCT cis rs1008375 1.000 rs12507142 chr4:17656103 A/G cg16339924 chr4:17578868 LAP3 0.63 5.26 0.43 6.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs782590 0.967 rs1084522 chr2:55843294 A/G cg03859395 chr2:55845619 SMEK2 0.88 10.82 0.7 1.31e-19 Metabolic syndrome; TGCT trans rs1973993 0.691 rs6658131 chr1:96889314 C/T cg10631902 chr5:14652156 NA 0.39 10.65 0.69 3.39e-19 Weight; TGCT cis rs210152 0.588 rs1755040 chr6:33495175 A/C cg07735790 chr6:34101545 GRM4 -0.52 -4.79 -0.4 4.68e-6 Schizophrenia; TGCT cis rs6969780 0.722 rs4722666 chr7:27197601 C/G cg22997113 chr7:27170241 HOXA4 -0.44 -4.46 -0.37 1.79e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs752010 0.574 rs2148636 chr1:42119844 C/T cg06885757 chr1:42089581 HIVEP3 -0.25 -4.89 -0.4 3.08e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs1801251 1.000 rs6717841 chr2:233590255 C/T cg08000102 chr2:233561755 GIGYF2 0.63 6.53 0.51 1.51e-9 Coronary artery disease; TGCT cis rs7772486 0.790 rs6917135 chr6:146152426 T/C cg23711669 chr6:146136114 FBXO30 0.89 10.12 0.67 6.38e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 1.000 rs10939746 chr4:17684951 A/G cg18681998 chr4:17616180 MED28 -0.96 -10.78 -0.7 1.61e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.530 rs2865992 chr4:99067181 A/T cg17366294 chr4:99064904 C4orf37 0.58 6.15 0.48 9.93e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7246657 0.712 rs4803263 chr19:38066782 G/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs2404602 0.692 rs35999717 chr15:77193367 G/C cg26408565 chr15:76604113 ETFA -0.36 -4.68 -0.39 7.39e-6 Blood metabolite levels; TGCT cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg17747265 chr1:1875780 NA -0.39 -7.32 -0.55 2.73e-11 Body mass index; TGCT cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg27454412 chr7:1067447 C7orf50 0.57 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17270561 0.541 rs17586946 chr6:25939053 C/T cg16482183 chr6:26056742 HIST1H1C 0.95 7.23 0.54 4.29e-11 Iron status biomarkers; TGCT cis rs7615952 0.736 rs11921945 chr3:125643719 A/G cg05084668 chr3:125655381 ALG1L -0.7 -5.64 -0.45 1.08e-7 Blood pressure (smoking interaction); TGCT cis rs55940216 0.615 rs2027924 chr8:17983723 C/T cg24613644 chr8:18387969 PSD3 0.3 4.77 0.39 5.16e-6 Facial morphology (factor 14, intercanthal width); TGCT cis rs28595532 0.841 rs114175487 chr4:119733580 C/G cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg05896524 chr21:47604654 C21orf56 0.43 4.58 0.38 1.13e-5 Testicular germ cell tumor; TGCT cis rs597539 0.652 rs602364 chr11:68662167 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.04 0.59 5.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs1005277 0.522 rs1208681 chr10:38092975 C/T cg17830980 chr10:43048298 ZNF37B -0.65 -7.49 -0.56 1.11e-11 Extrinsic epigenetic age acceleration; TGCT cis rs3749237 0.595 rs10865955 chr3:49499829 G/A cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs3821902 0.606 rs73119095 chr3:64018177 G/T cg22134162 chr3:63841271 THOC7 -0.32 -4.77 -0.39 5.15e-6 Breast cancer; TGCT cis rs854765 0.686 rs8065497 chr17:17782649 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.65 -6.47 -0.5 2.03e-9 Total body bone mineral density; TGCT cis rs10504229 0.683 rs58438731 chr8:58134790 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT trans rs7613875 0.580 rs2624819 chr3:50010571 G/T cg21659725 chr3:3221576 CRBN 0.7 7.96 0.58 9.35e-13 Body mass index; TGCT cis rs60843830 1.000 rs56167434 chr2:282137 G/C cg25945732 chr2:264204 ACP1;SH3YL1 0.72 6.95 0.53 1.86e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9733 0.543 rs72702558 chr1:150683251 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs9383153 0.590 rs2072736 chr6:16328068 T/C cg20052079 chr6:15504923 JARID2 0.92 5.01 0.41 1.82e-6 Gambling; TGCT cis rs1552244 0.882 rs55840655 chr3:10042690 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs4631830 0.683 rs10763193 chr10:51504938 G/A cg10326726 chr10:51549505 MSMB 0.23 4.54 0.38 1.33e-5 Prostate-specific antigen levels; TGCT cis rs7824557 0.564 rs2736301 chr8:11236413 C/T cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs7833790 1.000 rs28696138 chr8:82770794 G/A cg27398817 chr8:82754497 SNX16 0.84 5.98 0.47 2.18e-8 Diastolic blood pressure; TGCT cis rs12291225 0.679 rs4757245 chr11:14297872 A/C cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs1062177 1.000 rs41494545 chr5:151235094 A/G cg00977110 chr5:151150581 G3BP1 -0.4 -4.5 -0.38 1.51e-5 Preschool internalizing problems; TGCT cis rs7175404 0.591 rs17708628 chr15:94060378 T/C cg18324227 chr15:93584571 NA 0.49 4.56 0.38 1.2e-5 Attention deficit hyperactivity disorder; TGCT cis rs8031584 0.652 rs2691683 chr15:31135060 A/G cg08704250 chr15:31115839 NA 0.43 6.31 0.49 4.47e-9 Huntington's disease progression; TGCT cis rs372883 0.613 rs1153289 chr21:30686212 G/T cg24692254 chr21:30365293 RNF160 -0.5 -4.55 -0.38 1.25e-5 Pancreatic cancer; TGCT cis rs7698623 0.850 rs4693896 chr4:88797897 T/C cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs6722750 0.933 rs1370390 chr2:64410193 G/T cg22352474 chr2:64371530 PELI1 0.58 5.18 0.42 8.78e-7 Neuroticism; TGCT cis rs12477438 0.798 rs6704766 chr2:99642818 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs1475911 1.000 rs34421316 chr21:43513989 C/T cg14562523 chr21:43528734 C21orf128;UMODL1 -0.26 -5.08 -0.42 1.32e-6 IgG glycosylation; TGCT cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs7267979 0.966 rs6083817 chr20:25343998 G/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7937682 0.632 rs4441050 chr11:111772506 C/T cg09085632 chr11:111637200 PPP2R1B 0.84 7.34 0.55 2.4e-11 Primary sclerosing cholangitis; TGCT cis rs4132699 0.683 rs9410474 chr9:92012720 C/T cg00420568 chr9:91794904 SHC3 0.41 4.68 0.39 7.41e-6 Orofacial clefts;Nonsyndromic cleft lip with or without cleft palate; TGCT cis rs1975974 1.000 rs4889732 chr17:21721443 T/C cg18423549 chr17:21743878 NA -0.49 -4.65 -0.39 8.23e-6 Psoriasis; TGCT cis rs7666738 0.861 rs5014702 chr4:99052102 C/A cg05340658 chr4:99064831 C4orf37 0.51 5.67 0.45 9.57e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7412746 0.658 rs6677420 chr1:150946490 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.72 0.39 6.28e-6 Melanoma; TGCT cis rs4819052 0.851 rs7275870 chr21:46671214 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8017423 0.647 rs11623736 chr14:90746471 G/T cg04374321 chr14:90722782 PSMC1 -0.73 -6.99 -0.53 1.53e-10 Mortality in heart failure; TGCT cis rs7178424 0.516 rs12917535 chr15:62325518 A/T cg00456672 chr15:62358751 C2CD4A -0.29 -4.5 -0.37 1.52e-5 Height; TGCT cis rs12049351 0.613 rs10799535 chr1:229657794 T/C cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs11098499 0.863 rs3775849 chr4:120450908 G/C cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg02353165 chr6:42928485 GNMT 0.99 10.14 0.67 5.65e-18 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2075371 0.863 rs12672691 chr7:133954431 C/T cg11752832 chr7:134001865 SLC35B4 0.66 5.52 0.44 1.93e-7 Mean platelet volume; TGCT cis rs57590327 0.503 rs9866374 chr3:81615311 T/C cg07356753 chr3:81810745 GBE1 -0.61 -5.1 -0.42 1.24e-6 Extraversion; TGCT cis rs6912958 0.515 rs381782 chr6:88040649 C/T cg10393598 chr6:87862264 NA -0.31 -4.5 -0.37 1.54e-5 Monocyte percentage of white cells; TGCT trans rs210152 0.531 rs4713634 chr6:33514708 T/C cg22108809 chr5:56777663 ACTBL2 -0.54 -6.67 -0.51 7.5e-10 Schizophrenia; TGCT cis rs4689388 0.926 rs4689394 chr4:6291003 C/G cg25554036 chr4:6271136 WFS1 -0.54 -7.55 -0.56 8.15e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg00149659 chr3:10157352 C3orf10 0.94 6.0 0.47 2e-8 Alzheimer's disease; TGCT cis rs3125734 0.633 rs1864836 chr10:64028538 C/G cg09941381 chr10:64027924 RTKN2 -0.37 -5.64 -0.45 1.1e-7 Rheumatoid arthritis; TGCT cis rs2839186 0.770 rs2280956 chr21:47642323 C/G cg13732083 chr21:47605072 C21orf56 -0.36 -4.72 -0.39 6.26e-6 Testicular germ cell tumor; TGCT cis rs7647973 1.000 rs62259933 chr3:49469703 G/A cg06212747 chr3:49208901 KLHDC8B -0.57 -4.56 -0.38 1.21e-5 Menarche (age at onset); TGCT cis rs3849570 0.643 rs9870954 chr3:81978850 A/G cg07356753 chr3:81810745 GBE1 -0.64 -5.59 -0.45 1.4e-7 Waist circumference;Body mass index; TGCT cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg06481639 chr22:41940642 POLR3H -0.73 -6.64 -0.51 8.91e-10 Vitiligo; TGCT cis rs1008375 1.000 rs6846238 chr4:17629939 A/G cg16339924 chr4:17578868 LAP3 0.62 5.11 0.42 1.17e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13242816 1.000 rs6968230 chr7:116137049 G/T cg16553024 chr7:116138462 CAV2 -0.44 -5.31 -0.43 4.81e-7 P wave duration; TGCT cis rs2637266 0.935 rs7921790 chr10:78368253 T/C cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs57221529 0.766 rs4957053 chr5:575927 T/C cg20362242 chr5:692897 TPPP 0.48 4.51 0.38 1.47e-5 Lung disease severity in cystic fibrosis; TGCT cis rs6725041 0.522 rs10172782 chr2:213089415 C/G cg16329650 chr2:213403929 ERBB4 -0.55 -4.78 -0.39 4.82e-6 QT interval (ambient particulate matter interaction); TGCT cis rs42648 0.869 rs42614 chr7:89950363 C/G cg25739043 chr7:89950458 NA -0.74 -7.3 -0.55 2.98e-11 Homocysteine levels; TGCT cis rs3806843 0.933 rs2240696 chr5:140168070 A/G cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg03806693 chr22:41940476 POLR3H 1.02 11.39 0.72 5.21e-21 Vitiligo; TGCT cis rs7267979 1.000 rs2257985 chr20:25269743 G/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9818758 0.607 rs9847839 chr3:49289003 T/C cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9911578 0.934 rs8081967 chr17:57072701 T/C cg05425664 chr17:57184151 TRIM37 -0.68 -6.89 -0.53 2.55e-10 Intelligence (multi-trait analysis); TGCT cis rs4808199 0.947 rs10401193 chr19:19591066 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.69 4.99 0.41 1.96e-6 Nonalcoholic fatty liver disease; TGCT cis rs9790314 0.846 rs13083229 chr3:161008125 G/A cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg02187348 chr16:89574699 SPG7 0.63 6.99 0.53 1.47e-10 Multiple myeloma (IgH translocation); TGCT cis rs10504229 0.683 rs7820302 chr8:58142502 C/T cg02725872 chr8:58115012 NA -0.35 -4.67 -0.39 7.82e-6 Developmental language disorder (linguistic errors); TGCT cis rs7614311 0.681 rs73117083 chr3:63948455 G/C cg22134162 chr3:63841271 THOC7 -0.46 -5.87 -0.47 3.73e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs56399783 0.901 rs17300022 chr7:2808517 C/T cg19731401 chr7:2775893 GNA12 -0.37 -5.15 -0.42 1.01e-6 Childhood ear infection; TGCT cis rs2486012 1.000 rs2485989 chr1:44408454 T/C cg12908607 chr1:44402522 ARTN 0.77 6.02 0.48 1.79e-8 Intelligence (multi-trait analysis); TGCT cis rs3935685 0.934 rs11630598 chr15:78006095 C/T cg25212270 chr15:78015279 NA 0.3 6.08 0.48 1.38e-8 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.754 rs1051131 chr6:88221546 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg22963979 chr7:1858916 MAD1L1 -0.34 -5.39 -0.44 3.43e-7 Bipolar disorder and schizophrenia; TGCT cis rs6540559 0.551 rs17389436 chr1:209972297 A/T cg21951975 chr1:209979733 IRF6 0.73 4.68 0.39 7.53e-6 Cleft lip with or without cleft palate; TGCT cis rs7829975 0.688 rs6601703 chr8:8380224 A/G cg08975724 chr8:8085496 FLJ10661 0.64 6.03 0.48 1.77e-8 Mood instability; TGCT cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs76096589 0.557 rs59230713 chr14:50995729 A/C cg04730355 chr14:51134070 SAV1 1.05 4.49 0.37 1.58e-5 Diisocyanate-induced asthma; TGCT cis rs1372520 0.577 rs748849 chr4:90734961 G/A cg20003494 chr4:90757398 SNCA -0.65 -5.2 -0.42 8.15e-7 Neuroticism; TGCT cis rs72781680 0.898 rs72782113 chr2:24024952 G/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg03060546 chr3:49711283 APEH -0.51 -4.92 -0.4 2.75e-6 Menarche (age at onset); TGCT cis rs3774830 0.743 rs6810392 chr4:5459932 C/T cg26943120 chr4:5472116 STK32B 0.22 4.78 0.39 4.95e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1949733 0.701 rs871768 chr4:8454938 G/A cg11789530 chr4:8429930 ACOX3 0.54 5.13 0.42 1.08e-6 Response to antineoplastic agents; TGCT cis rs7208859 0.673 rs216411 chr17:28903493 T/C cg13385521 chr17:29058706 SUZ12P -0.76 -4.71 -0.39 6.4e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg10295955 chr4:187884368 NA -0.99 -14.5 -0.79 1.78e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs8077889 0.956 rs4793026 chr17:41850508 A/G cg26893861 chr17:41843967 DUSP3 1.09 13.68 0.78 1.57e-26 Triglycerides; TGCT cis rs13256369 0.901 rs12681327 chr8:8566414 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs7267979 1.000 rs6050542 chr20:25318879 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9457247 1.000 rs393558 chr6:167397750 A/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs12142240 0.698 rs72677594 chr1:46824371 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7542091 0.748 rs2357231 chr1:210028454 A/C cg22029157 chr1:209979665 IRF6 -0.48 -4.83 -0.4 4.03e-6 Monobrow; TGCT cis rs826838 0.935 rs3886109 chr12:39189243 C/T cg26384229 chr12:38710491 ALG10B 0.98 8.78 0.62 1.07e-14 Heart rate; TGCT trans rs6089829 0.888 rs6011559 chr20:61675620 C/T cg13615516 chr5:77269221 NA -0.73 -8.16 -0.59 3.24e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs908922 0.676 rs1856119 chr1:152512483 A/G cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs4822044 0.568 rs1883370 chr22:42143740 C/A cg06481639 chr22:41940642 POLR3H 0.67 5.81 0.46 5.06e-8 Cannabis dependence symptom count; TGCT trans rs57221529 0.766 rs72703064 chr5:587825 T/C cg11887960 chr12:57824829 NA 1.14 9.3 0.64 6.29e-16 Lung disease severity in cystic fibrosis; TGCT cis rs9527 0.590 rs12415388 chr10:104796345 T/C cg15744005 chr10:104629667 AS3MT -0.4 -4.63 -0.38 9.04e-6 Arsenic metabolism; TGCT cis rs1150668 0.799 rs7206 chr6:28201138 A/G cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.61 -0.38 9.84e-6 Pubertal anthropometrics; TGCT cis rs8002180 0.918 rs7322318 chr13:95923688 T/C cg24476569 chr13:95954382 ABCC4 0.41 5.09 0.42 1.31e-6 Blood metabolite levels; TGCT cis rs11648796 0.879 rs12448432 chr16:778820 G/A cg00908189 chr16:619842 PIGQ 0.68 5.44 0.44 2.68e-7 Height; TGCT cis rs78456975 1.000 rs10189336 chr2:1558015 G/A cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg00024416 chr22:24240387 NA 0.3 5.49 0.44 2.2e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17376456 0.741 rs7718842 chr5:93480568 G/A cg21475434 chr5:93447410 FAM172A 0.62 4.57 0.38 1.16e-5 Diabetic retinopathy; TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg10819733 chr22:24237672 NA -0.3 -5.01 -0.41 1.87e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10057188 0.545 rs13162495 chr5:77929230 C/T cg17456851 chr5:78090622 ARSB -0.28 -4.51 -0.38 1.49e-5 Pulse pressure; TGCT cis rs1355223 0.583 rs1828298 chr11:34870439 A/G cg11058730 chr11:34937778 PDHX;APIP 0.78 8.67 0.61 2.03e-14 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs7666738 0.830 rs4699588 chr4:98973789 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs57920188 0.535 rs4295856 chr1:4094842 C/T cg20703997 chr1:4087676 NA 0.48 5.7 0.46 8.27e-8 Interleukin-17 levels; TGCT cis rs61931739 0.517 rs7139189 chr12:34319757 T/C cg06521331 chr12:34319734 NA -0.35 -5.74 -0.46 6.71e-8 Morning vs. evening chronotype; TGCT cis rs769267 0.930 rs3794990 chr19:19610030 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs9486715 0.790 rs2971602 chr6:97022468 C/T cg06623918 chr6:96969491 KIAA0776 -1.1 -14.44 -0.79 2.5e-28 Headache; TGCT cis rs11785400 0.793 rs6996760 chr8:143722386 G/A cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.7e-7 Schizophrenia; TGCT cis rs4938534 0.683 rs1944930 chr11:111290238 G/A cg24049888 chr11:111250129 POU2AF1 -0.25 -4.44 -0.37 1.98e-5 Primary biliary cholangitis; TGCT cis rs1008375 0.966 rs2302393 chr4:17654341 G/A cg10189774 chr4:17578691 LAP3 0.55 4.91 0.4 2.81e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2120019 0.935 rs12591119 chr15:75355944 A/G cg09165964 chr15:75287851 SCAMP5 -1.18 -9.83 -0.66 3.33e-17 Blood trace element (Zn levels); TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg08859206 chr1:53392774 SCP2 -0.48 -7.66 -0.57 4.69e-12 Monocyte count; TGCT cis rs2243480 1.000 rs2420170 chr7:65656053 T/C cg20637647 chr7:64974828 NA -0.92 -5.09 -0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg15691649 chr6:25882328 NA -0.41 -4.77 -0.39 4.99e-6 Intelligence (multi-trait analysis); TGCT trans rs6762477 0.748 rs2073726 chr3:50223593 T/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.78 -8.11 -0.59 4.24e-13 Menarche (age at onset); TGCT cis rs1568889 1.000 rs1464897 chr11:28034844 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.87 8.85 0.62 7.64e-15 Bipolar disorder; TGCT cis rs28493229 0.708 rs10407431 chr19:41160870 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.94e-7 Kawasaki disease; TGCT trans rs1814175 0.935 rs10839317 chr11:49657228 A/C cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs2663905 0.611 rs2663924 chr15:81392903 T/G cg27045999 chr15:81426544 C15orf26 -0.51 -5.02 -0.41 1.78e-6 QT interval (drug interaction); TGCT cis rs3806843 0.766 rs801176 chr5:140087010 A/G cg19875535 chr5:140030758 IK 0.36 6.02 0.48 1.85e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs1505368 0.781 rs10197836 chr2:213274278 T/C cg16329650 chr2:213403929 ERBB4 0.61 5.92 0.47 2.88e-8 Symmetrical dimethylarginine levels; TGCT cis rs7980687 0.527 rs1727295 chr12:123616861 G/A cg00376283 chr12:123451042 ABCB9 0.76 6.75 0.52 5.13e-10 Height;Educational attainment;Head circumference (infant); TGCT cis rs17473412 0.677 rs6887967 chr5:122884414 A/G cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs28595532 0.920 rs28837152 chr4:119782868 G/A cg21605333 chr4:119757512 SEC24D 1.44 8.24 0.6 2.03e-13 Cannabis dependence symptom count; TGCT cis rs2456568 0.867 rs1827931 chr11:93663170 T/C cg26875233 chr11:93583750 C11orf90 -0.46 -5.74 -0.46 7.02e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs8077889 0.956 rs58242860 chr17:41847300 T/C cg26893861 chr17:41843967 DUSP3 1.09 13.68 0.78 1.57e-26 Triglycerides; TGCT cis rs3806843 0.545 rs251375 chr5:140252960 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.43 5.17 0.42 8.91e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs2242116 1.000 rs2242116 chr3:46941116 A/G cg23352942 chr3:46931381 PTH1R -0.36 -5.48 -0.44 2.27e-7 Birth weight; TGCT cis rs8017423 0.967 rs11623275 chr14:90721335 C/T cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.49e-12 Mortality in heart failure; TGCT cis rs7772486 0.748 rs2748484 chr6:146333653 C/T cg23711669 chr6:146136114 FBXO30 0.84 9.12 0.63 1.72e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs11098499 0.954 rs10006877 chr4:120242793 C/T cg09307838 chr4:120376055 NA 0.63 5.89 0.47 3.41e-8 Corneal astigmatism; TGCT cis rs875971 0.638 rs6960778 chr7:66071597 C/T cg00343986 chr7:65444356 GUSB -0.24 -5.3 -0.43 5.16e-7 Aortic root size; TGCT cis rs12477438 0.765 rs6750876 chr2:99679673 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs10791323 0.569 rs2282602 chr11:133714522 G/A cg03690763 chr11:133734501 NA -0.31 -4.82 -0.4 4.08e-6 Childhood ear infection; TGCT cis rs644799 0.544 rs687559 chr11:95598629 C/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.49 -4.98 -0.41 2.09e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2354432 0.556 rs34602039 chr1:146850972 G/A cg25205988 chr1:146714368 CHD1L -1.34 -5.79 -0.46 5.52e-8 Mitochondrial DNA levels; TGCT cis rs2243480 0.901 rs778693 chr7:65872345 T/G cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs7605378 0.528 rs281787 chr2:200784238 C/T cg23649088 chr2:200775458 C2orf69 -0.47 -9.83 -0.66 3.23e-17 Osteoporosis; TGCT cis rs13108904 0.517 rs4974551 chr4:1336410 C/A cg13395646 chr4:1353034 KIAA1530 -0.55 -7.57 -0.56 7.56e-12 Obesity-related traits; TGCT cis rs4478858 0.684 rs4949202 chr1:31736800 T/C cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs67311347 0.577 rs2887951 chr3:40282104 C/G cg13683864 chr3:40499215 RPL14 -0.8 -7.63 -0.57 5.39e-12 Renal cell carcinoma; TGCT cis rs6740322 0.895 rs10166994 chr2:43557977 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.54 -0.51 1.45e-9 Coronary artery disease; TGCT cis rs644148 0.781 rs630469 chr19:44970167 T/C cg15540054 chr19:45004280 ZNF180 -0.59 -5.21 -0.42 7.8e-7 Personality dimensions; TGCT cis rs12497850 0.797 rs61583136 chr3:49189195 C/T cg07636037 chr3:49044803 WDR6 0.94 10.1 0.67 7.08e-18 Parkinson's disease; TGCT cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg22166914 chr1:53195759 ZYG11B -0.36 -5.96 -0.47 2.44e-8 Monocyte count; TGCT cis rs6121246 0.567 rs6087700 chr20:30217560 A/G cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs13064411 0.735 rs7636128 chr3:113133701 A/T cg18753928 chr3:113234510 CCDC52 -0.67 -5.12 -0.42 1.14e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs1552244 0.554 rs59465469 chr3:9990800 G/C cg00149659 chr3:10157352 C3orf10 0.67 4.96 0.41 2.28e-6 Alzheimer's disease; TGCT cis rs1372520 0.684 rs2197120 chr4:90729602 A/G cg14346243 chr4:90757452 SNCA -0.68 -5.64 -0.45 1.12e-7 Neuroticism; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg14820908 chr5:178986412 RUFY1 0.61 6.78 0.52 4.37e-10 Lung cancer; TGCT cis rs909002 0.830 rs1356803 chr1:32131163 C/G cg11573219 chr1:32083031 HCRTR1 -0.42 -5.36 -0.43 3.92e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs921522 chr4:98841608 C/T cg17366294 chr4:99064904 C4orf37 0.66 6.12 0.48 1.11e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10791323 0.572 rs1114367 chr11:133737304 G/T cg15485101 chr11:133734466 NA 0.43 6.26 0.49 5.61e-9 Childhood ear infection; TGCT cis rs60871478 0.947 rs62432255 chr7:804219 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.48 4.88 0.4 3.21e-6 Cerebrospinal P-tau181p levels; TGCT cis rs4972806 0.849 rs2857535 chr2:177036211 G/A cg13092806 chr2:177043255 NA 0.54 4.66 0.39 7.93e-6 IgG glycosylation; TGCT cis rs9914988 0.943 rs9890155 chr17:27125467 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs35306767 0.953 rs12259801 chr10:959306 C/G cg26597838 chr10:835615 NA 0.66 9.01 0.63 3.04e-15 Eosinophil percentage of granulocytes; TGCT cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg10802521 chr3:52805072 NEK4 0.72 9.04 0.63 2.63e-15 Bipolar disorder; TGCT cis rs7666738 0.791 rs1426661 chr4:98874303 C/G cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 1.000 rs6925703 chr6:26521589 G/A cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs6540559 0.673 rs7525951 chr1:210018306 C/T cg21951975 chr1:209979733 IRF6 -0.63 -4.76 -0.39 5.36e-6 Cleft lip with or without cleft palate; TGCT cis rs7119 0.604 rs907383 chr15:77870646 A/G cg27398640 chr15:77910606 LINGO1 0.27 4.93 0.4 2.57e-6 Type 2 diabetes; TGCT cis rs7949030 0.725 rs12808829 chr11:62378660 G/A cg13298116 chr11:62369859 EML3;MTA2 0.66 9.9 0.66 2.21e-17 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9330316 0.632 rs56364682 chr2:110321230 A/G cg25199208 chr2:109402912 CCDC138 -0.42 -4.56 -0.38 1.19e-5 Schizophrenia; TGCT cis rs7085104 0.660 rs7902804 chr10:104585405 A/T cg05855489 chr10:104503620 C10orf26 0.52 4.64 0.38 8.83e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs2658782 1.000 rs2658779 chr11:93163137 G/T cg15737290 chr11:93063684 CCDC67 -0.77 -5.41 -0.44 3.09e-7 Pulmonary function decline; TGCT cis rs9467711 0.659 rs66941101 chr6:26530376 C/T cg16898833 chr6:26189333 HIST1H4D 1.25 5.86 0.47 3.88e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs6570726 0.935 rs452552 chr6:145820781 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4689388 0.750 rs12642481 chr4:6301058 G/A cg25554036 chr4:6271136 WFS1 0.57 7.14 0.54 6.76e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12893668 0.572 rs4906350 chr14:104111794 C/T cg26031613 chr14:104095156 KLC1 -0.59 -5.08 -0.42 1.34e-6 Reticulocyte count; TGCT cis rs10089 0.904 rs2228112 chr5:127469859 A/G cg19767477 chr5:127420684 SLC12A2 -0.43 -4.56 -0.38 1.21e-5 Ileal carcinoids; TGCT cis rs6460942 0.915 rs62448623 chr7:12464122 A/G cg06484146 chr7:12443880 VWDE -0.57 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT trans rs797680 0.856 rs7553465 chr1:93644410 C/T cg27528825 chr2:159282178 CCDC148 -0.35 -6.85 -0.52 3.08e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs4478858 0.684 rs4949202 chr1:31736800 T/C cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs2180341 1.000 rs6569482 chr6:127631371 C/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs4568518 0.530 rs6967917 chr7:17984297 A/G cg03009463 chr7:17980271 SNX13 0.57 4.61 0.38 9.88e-6 Measles; TGCT cis rs11031096 0.803 rs2099875 chr11:4173173 A/C cg18678763 chr11:4115507 RRM1 0.39 5.29 0.43 5.36e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs34779708 0.931 rs12771399 chr10:35452377 C/T cg04310649 chr10:35416472 CREM -0.53 -4.8 -0.4 4.46e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs28595532 0.920 rs17257039 chr4:119603703 G/A cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.12e-11 Cannabis dependence symptom count; TGCT cis rs17102423 0.788 rs11158575 chr14:65581665 T/C cg11161011 chr14:65562177 MAX -0.54 -7.62 -0.56 5.58e-12 Obesity-related traits; TGCT cis rs7027203 0.557 rs2487015 chr9:96521240 T/G cg14598338 chr9:96623480 NA -0.49 -7.04 -0.53 1.18e-10 DNA methylation (variation); TGCT cis rs782590 0.967 rs6545506 chr2:55798108 A/G cg03859395 chr2:55845619 SMEK2 -0.88 -10.87 -0.7 9.74e-20 Metabolic syndrome; TGCT cis rs1862618 0.671 rs173763 chr5:56225418 G/A cg24531977 chr5:56204891 C5orf35 -0.68 -7.22 -0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs10883723 0.738 rs3781290 chr10:104244948 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 8.62 0.61 2.63e-14 Allergic disease (asthma, hay fever or eczema); TGCT trans rs1814175 0.715 rs1722007 chr11:49897319 T/C cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.86e-13 Height; TGCT cis rs1552244 0.744 rs6763366 chr3:10033544 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs12681287 0.608 rs13272148 chr8:87481853 T/C cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs7267979 0.966 rs2257233 chr20:25265984 A/C cg16686733 chr20:25566563 NINL -0.56 -5.53 -0.44 1.84e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9796 0.653 rs28516683 chr15:41446645 A/G cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.83 -0.52 3.38e-10 Menopause (age at onset); TGCT cis rs9733 0.650 rs6698495 chr1:150564476 T/C cg13175981 chr1:150552382 MCL1 0.53 5.93 0.47 2.8e-8 Tonsillectomy; TGCT cis rs2836950 0.565 rs7279497 chr21:40531306 A/G cg06238570 chr21:40685208 BRWD1 0.56 5.77 0.46 5.85e-8 Menarche (age at onset); TGCT cis rs2216164 0.966 rs7137814 chr12:68571378 A/G cg17065850 chr12:67807625 NA -0.23 -4.48 -0.37 1.69e-5 Alopecia areata; TGCT cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.6 5.75 0.46 6.48e-8 Prudent dietary pattern; TGCT cis rs7772486 0.743 rs9390344 chr6:146012755 C/G cg23711669 chr6:146136114 FBXO30 -0.81 -8.65 -0.61 2.25e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs67311347 0.866 rs9826419 chr3:40352051 G/A cg13683864 chr3:40499215 RPL14 -0.91 -8.78 -0.62 1.08e-14 Renal cell carcinoma; TGCT cis rs11792861 0.926 rs72607174 chr9:111899132 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.47 0.37 1.73e-5 Menarche (age at onset); TGCT cis rs11098499 0.662 rs13108589 chr4:120268102 G/C cg09307838 chr4:120376055 NA 0.62 6.26 0.49 5.61e-9 Corneal astigmatism; TGCT cis rs2948294 0.588 rs4840913 chr8:8116906 A/C cg15556689 chr8:8085844 FLJ10661 0.69 6.05 0.48 1.56e-8 Red cell distribution width; TGCT cis rs6088580 0.634 rs4911422 chr20:32999345 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs28595532 0.920 rs56162974 chr4:119742333 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs986417 1.000 rs1254303 chr14:60886301 A/G cg27398547 chr14:60952738 C14orf39 -1.42 -8.68 -0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs9393777 0.557 rs7759741 chr6:27241043 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.58 -5.0 -0.41 1.95e-6 Intelligence (multi-trait analysis); TGCT cis rs9308731 0.623 rs2241841 chr2:111879467 G/A cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.18e-9 Chronic lymphocytic leukemia; TGCT cis rs3820928 0.874 rs116652884 chr2:227902285 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs590121 0.876 rs6704 chr11:75283653 C/A cg26104986 chr11:75275303 SERPINH1 -0.24 -4.53 -0.38 1.35e-5 Coronary artery disease; TGCT cis rs28595532 0.920 rs114051506 chr4:119772893 A/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs6964587 1.000 rs12537846 chr7:91721581 C/T cg22709100 chr7:91322751 NA -0.29 -4.82 -0.4 4.04e-6 Breast cancer; TGCT cis rs42648 0.792 rs4236517 chr7:89963465 A/T cg25739043 chr7:89950458 NA -0.67 -6.52 -0.51 1.63e-9 Homocysteine levels; TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg24675658 chr1:53192096 ZYG11B -0.73 -8.62 -0.61 2.59e-14 Monocyte count; TGCT cis rs3806843 0.931 rs13168670 chr5:140146899 T/C cg19875535 chr5:140030758 IK 0.37 6.23 0.49 6.53e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs597539 0.652 rs584108 chr11:68630282 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.82 -7.67 -0.57 4.3e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9467711 0.606 rs9357006 chr6:26364628 A/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs10858047 0.883 rs7539721 chr1:115171649 C/T cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs473651 0.901 rs563282 chr2:239329736 T/C cg18131467 chr2:239335373 ASB1 1.01 13.17 0.76 2.51e-25 Multiple system atrophy; TGCT cis rs10791323 0.572 rs10791334 chr11:133735810 A/C cg03690763 chr11:133734501 NA -0.28 -4.69 -0.39 7.17e-6 Childhood ear infection; TGCT cis rs57590327 0.716 rs4352391 chr3:81802318 T/C cg07356753 chr3:81810745 GBE1 -0.75 -6.83 -0.52 3.4e-10 Extraversion; TGCT cis rs10197940 0.571 rs13393021 chr2:152413258 A/C cg06191203 chr2:152266755 RIF1 -0.75 -7.03 -0.53 1.21e-10 Lung cancer; TGCT cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.529 rs6060144 chr20:30178624 A/G cg13852791 chr20:30311386 BCL2L1 0.71 4.54 0.38 1.31e-5 Mean corpuscular hemoglobin; TGCT cis rs9486719 0.857 rs6568392 chr6:96861476 G/T cg06623918 chr6:96969491 KIAA0776 1.0 11.25 0.71 1.12e-20 Migraine;Coronary artery disease; TGCT cis rs2657888 0.628 rs3809122 chr12:56882710 A/T cg23002907 chr12:56915593 RBMS2 -0.4 -5.24 -0.43 6.7e-7 Adiponectin levels; TGCT trans rs10435719 0.899 rs9693925 chr8:11789963 A/G cg15556689 chr8:8085844 FLJ10661 0.74 7.04 0.53 1.17e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT trans rs7618501 0.521 rs3796386 chr3:49899795 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.85 8.84 0.62 7.83e-15 Intelligence (multi-trait analysis); TGCT cis rs9682041 0.736 rs34237232 chr3:170063753 C/T cg11886554 chr3:170076028 SKIL -0.79 -5.52 -0.44 1.92e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs8180040 0.966 rs6800271 chr3:47470787 A/T cg27129171 chr3:47204927 SETD2 -0.68 -8.11 -0.59 4.16e-13 Colorectal cancer; TGCT cis rs9926296 0.712 rs447735 chr16:89734349 T/C cg27121462 chr16:89883253 FANCA -0.55 -5.11 -0.42 1.2e-6 Vitiligo; TGCT cis rs1552244 0.882 rs3732967 chr3:10015437 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs6964587 0.933 rs28671255 chr7:91770705 A/G cg17063962 chr7:91808500 NA 0.91 9.8 0.66 3.89e-17 Breast cancer; TGCT cis rs9926296 0.568 rs4420527 chr16:89814188 C/T cg03388025 chr16:89894329 SPIRE2 -0.49 -8.45 -0.6 6.47e-14 Vitiligo; TGCT cis rs854765 0.724 rs62072049 chr17:17906520 T/C cg04398451 chr17:18023971 MYO15A -0.29 -4.54 -0.38 1.33e-5 Total body bone mineral density; TGCT cis rs9894429 1.000 rs7222241 chr17:79574714 C/G cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT trans rs4650994 0.544 rs2811306 chr1:178599248 C/G cg05059571 chr16:84539110 KIAA1609 0.52 10.37 0.68 1.56e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7822232 1.000 rs6558296 chr8:145143802 G/A cg06495924 chr8:145149574 CYC1 -1.04 -4.49 -0.37 1.6e-5 Blood metabolite levels; TGCT cis rs769267 0.965 rs4808200 chr19:19554803 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.63 5.19 0.42 8.51e-7 Tonsillectomy; TGCT cis rs1008375 1.000 rs6854733 chr4:17640526 C/T cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs453301 0.686 rs11785819 chr8:8870378 T/G cg15556689 chr8:8085844 FLJ10661 -0.64 -5.29 -0.43 5.37e-7 Joint mobility (Beighton score); TGCT cis rs13188771 0.651 rs12520498 chr5:100881358 G/A cg18665594 chr5:101119420 NA 0.45 4.5 0.37 1.55e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs4862750 0.914 rs9995391 chr4:187873749 A/T cg03452623 chr4:187889614 NA 0.34 4.58 0.38 1.11e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg13683864 chr3:40499215 RPL14 1.14 12.22 0.74 4.89e-23 Renal cell carcinoma; TGCT cis rs2046867 0.818 rs34582798 chr3:72882778 A/C cg25664220 chr3:72788482 NA -0.57 -6.33 -0.49 4.08e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6570726 0.791 rs9403729 chr6:145907007 C/T cg05347473 chr6:146136440 FBXO30 0.54 5.12 0.42 1.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6681544 0.760 rs2172285 chr1:82411874 C/T cg04226724 chr1:82268649 LPHN2 -0.48 -4.95 -0.41 2.42e-6 Metabolite levels (X-11787); TGCT cis rs17331151 0.505 rs79993196 chr3:52697566 T/C cg07884673 chr3:53033167 SFMBT1 0.75 5.59 0.45 1.35e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10256972 0.567 rs2960850 chr7:1211649 A/G cg07092213 chr7:1199455 ZFAND2A -0.46 -4.74 -0.39 5.68e-6 Longevity;Endometriosis; TGCT cis rs8056742 0.730 rs71386886 chr16:85065488 G/C cg00229868 chr16:85520891 NA 0.42 5.17 0.42 9.14e-7 Amyotrophic lateral sclerosis; TGCT cis rs28595532 0.920 rs55726697 chr4:119742863 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg03806693 chr22:41940476 POLR3H -1.15 -12.98 -0.76 7.24e-25 Vitiligo; TGCT cis rs10892173 0.846 rs7943887 chr11:117670282 C/G cg21640587 chr11:117668038 DSCAML1 0.41 4.58 0.38 1.13e-5 Myopia; TGCT cis rs4654899 0.785 rs9426656 chr1:21505932 T/G cg01072550 chr1:21505969 NA -0.57 -9.4 -0.64 3.62e-16 Superior frontal gyrus grey matter volume; TGCT cis rs7666738 1.000 rs13106934 chr4:99028685 C/T cg05340658 chr4:99064831 C4orf37 0.46 4.57 0.38 1.18e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs6460942 0.915 rs62448596 chr7:12446869 C/T cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs7582180 0.625 rs11892034 chr2:100938952 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs4072705 0.616 rs915033 chr9:127245558 C/G cg13476313 chr9:127244764 NR5A1 0.31 5.09 0.42 1.29e-6 Menarche (age at onset); TGCT cis rs854765 0.583 rs9912895 chr17:17826020 C/T cg09796270 chr17:17721594 SREBF1 -0.24 -4.86 -0.4 3.44e-6 Total body bone mineral density; TGCT cis rs12472274 0.817 rs12621791 chr2:239104061 G/A cg17459225 chr2:239074497 NA 0.33 4.84 0.4 3.79e-6 Phospholipid levels (plasma); TGCT cis rs2456568 0.802 rs7101791 chr11:93638998 A/G cg14065697 chr11:93583672 C11orf90 -0.38 -4.74 -0.39 5.65e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9399135 0.967 rs9389251 chr6:135325717 A/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs727505 1.000 rs10241173 chr7:124453258 A/G cg23710748 chr7:124431027 NA -0.26 -4.5 -0.37 1.54e-5 Lewy body disease; TGCT cis rs644799 1.000 rs516551 chr11:95588626 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.55 0.61 3.94e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9549367 1.000 rs9549367 chr13:113911532 C/G cg18105134 chr13:113819100 PROZ -0.32 -5.2 -0.42 7.84e-7 Platelet distribution width; TGCT cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.94 9.46 0.65 2.58e-16 Intelligence (multi-trait analysis); TGCT cis rs897984 0.806 rs1046276 chr16:30914626 A/G cg02466173 chr16:30829666 NA 0.27 4.51 0.38 1.47e-5 Dementia with Lewy bodies; TGCT trans rs941408 1.000 rs1076448 chr19:2792343 G/A cg22153745 chr1:153894579 GATAD2B -0.64 -7.26 -0.55 3.67e-11 Total cholesterol levels; TGCT cis rs473651 0.935 rs472357 chr2:239355454 A/G cg18131467 chr2:239335373 ASB1 -1.01 -14.84 -0.8 2.9e-29 Multiple system atrophy; TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs12477438 0.765 rs12468807 chr2:99691994 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs17376456 0.569 rs1349711 chr5:93179032 C/T cg21475434 chr5:93447410 FAM172A -0.64 -4.75 -0.39 5.47e-6 Diabetic retinopathy; TGCT cis rs28374715 0.681 rs7163989 chr15:41614621 A/G cg18705301 chr15:41695430 NDUFAF1 -0.87 -13.41 -0.77 7e-26 Ulcerative colitis; TGCT cis rs6089829 0.889 rs6062773 chr20:61663262 G/C cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs66561647 0.719 rs4733582 chr8:128947967 C/T cg11792826 chr8:129160931 MIR1208 0.21 4.73 0.39 6.13e-6 Hemoglobin concentration; TGCT cis rs7044106 0.648 rs2031369 chr9:123360294 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.55 5.59 0.45 1.36e-7 Hip circumference adjusted for BMI; TGCT cis rs9303401 0.659 rs34426768 chr17:56683385 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs10782582 0.609 rs6656501 chr1:76266126 A/C cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Vitiligo; TGCT cis rs1903068 0.853 rs9312657 chr4:56003502 G/A cg16572876 chr4:56024045 NA 0.42 4.79 0.39 4.75e-6 Endometriosis; TGCT cis rs7666738 0.830 rs4699584 chr4:98952019 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10193935 0.786 rs72796504 chr2:42406728 T/C cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg17554472 chr22:41940697 POLR3H 0.49 5.06 0.41 1.44e-6 Vitiligo; TGCT cis rs5769707 0.605 rs6009791 chr22:50025265 T/C cg05373962 chr22:49881684 NA -0.31 -5.37 -0.43 3.8e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1552244 1.000 rs113522867 chr3:10154503 T/C cg00149659 chr3:10157352 C3orf10 0.94 6.0 0.47 2e-8 Alzheimer's disease; TGCT cis rs6940638 0.662 rs7759694 chr6:27240956 C/T cg15659132 chr6:26577336 NA -0.61 -5.84 -0.46 4.2e-8 Intelligence (multi-trait analysis); TGCT cis rs853679 0.550 rs6901017 chr6:28152583 T/C cg12963246 chr6:28129442 ZNF389 0.49 4.8 0.4 4.53e-6 Depression; TGCT cis rs62064224 0.530 rs8073708 chr17:30680493 T/C cg18200150 chr17:30822561 MYO1D 0.39 4.69 0.39 7.12e-6 Schizophrenia; TGCT cis rs7565124 1.000 rs12472043 chr2:20256838 G/A cg00462460 chr2:20212509 MATN3 -0.43 -4.67 -0.39 7.65e-6 Major depressive disorder; TGCT cis rs4821897 0.514 rs739141 chr22:39824450 A/G cg01416388 chr22:39784598 NA 0.64 6.62 0.51 9.94e-10 IgG glycosylation; TGCT cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg16405210 chr4:1374714 KIAA1530 -0.24 -4.44 -0.37 1.98e-5 Longevity; TGCT cis rs1775715 0.737 rs11008695 chr10:32216887 T/G cg14930904 chr10:32216787 ARHGAP12 0.53 5.05 0.41 1.51e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs7772486 0.790 rs6926657 chr6:146255794 G/A cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg21672276 chr3:44754072 ZNF502 -0.44 -4.89 -0.4 3.02e-6 Depressive symptoms; TGCT trans rs28735056 0.609 rs4799099 chr18:77639585 A/G cg05926928 chr17:57297772 GDPD1 0.83 9.68 0.66 7.66e-17 Schizophrenia; TGCT cis rs909002 0.800 rs2176807 chr1:32092735 T/G cg11573219 chr1:32083031 HCRTR1 -0.43 -5.6 -0.45 1.33e-7 Intelligence (multi-trait analysis); TGCT cis rs7804356 0.954 rs4722641 chr7:26838677 C/G cg03456212 chr7:26904342 SKAP2 -0.61 -4.7 -0.39 6.82e-6 Type 1 diabetes; TGCT cis rs35306767 0.714 rs12783621 chr10:1083304 C/T cg20503657 chr10:835505 NA 0.44 4.99 0.41 1.96e-6 Eosinophil percentage of granulocytes; TGCT cis rs79349575 0.749 rs2270574 chr17:47022270 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs4925386 0.625 rs3810550 chr20:60912117 C/T cg06026331 chr20:60912101 LAMA5 0.35 5.55 0.45 1.65e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs2458413 0.771 rs7010076 chr8:105342827 C/G cg04554929 chr8:105342491 NA -0.52 -7.4 -0.55 1.82e-11 Paget's disease; TGCT cis rs2594989 0.779 rs13353407 chr3:11585299 C/T cg00170343 chr3:11313890 ATG7 -0.68 -5.04 -0.41 1.64e-6 Circulating chemerin levels; TGCT trans rs6446298 1.000 rs6446298 chr3:49860854 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.77 6.88 0.53 2.69e-10 Intelligence (multi-trait analysis); TGCT cis rs5769765 0.908 rs9616217 chr22:50318946 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.21 -8.49 -0.61 5.29e-14 Schizophrenia; TGCT cis rs902774 0.585 rs7399070 chr12:53355678 G/T cg16329197 chr12:53359506 NA -0.56 -4.71 -0.39 6.44e-6 Prostate cancer; TGCT cis rs45509595 0.841 rs9368531 chr6:27781872 G/C cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.24e-6 Breast cancer; TGCT cis rs1865760 0.566 rs1800702 chr6:26086463 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs9467773 0.869 rs1796520 chr6:26410800 C/T cg24010402 chr6:26660753 ZNF322A 0.23 4.46 0.37 1.8e-5 Intelligence (multi-trait analysis); TGCT cis rs5769707 0.967 rs9616333 chr22:50050847 G/A cg10356904 chr22:49881777 NA -0.23 -4.53 -0.38 1.35e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10206020 0.921 rs72776302 chr2:1571383 G/A cg01028140 chr2:1542097 TPO -0.32 -4.99 -0.41 1.97e-6 IgG glycosylation; TGCT cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg03188948 chr7:1209495 NA 0.62 5.66 0.45 9.97e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7937682 0.924 rs564601 chr11:111594077 T/C cg09085632 chr11:111637200 PPP2R1B -1.17 -13.93 -0.78 3.92e-27 Primary sclerosing cholangitis; TGCT cis rs7267979 1.000 rs2482927 chr20:25327151 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7618501 0.633 rs12485600 chr3:50025530 A/G cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.85e-16 Intelligence (multi-trait analysis); TGCT cis rs2013441 1.000 rs11871945 chr17:20206883 A/G cg18979559 chr17:20280153 CCDC144C -0.49 -4.99 -0.41 1.97e-6 Obesity-related traits; TGCT cis rs62064224 0.614 rs11656445 chr17:30694164 T/C cg18200150 chr17:30822561 MYO1D 0.39 4.65 0.39 8.31e-6 Schizophrenia; TGCT cis rs72781680 0.821 rs17038360 chr2:24095798 A/G cg08917208 chr2:24149416 ATAD2B 0.77 4.89 0.4 3e-6 Lymphocyte counts; TGCT cis rs796364 0.587 rs7588746 chr2:200986345 A/G cg17644776 chr2:200775616 C2orf69 0.3 4.88 0.4 3.22e-6 Schizophrenia; TGCT cis rs79349575 0.783 rs4399576 chr17:47009835 G/A cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs12701220 0.894 rs10263252 chr7:1049949 G/A cg07217954 chr7:1067459 C7orf50 -0.49 -4.9 -0.4 2.95e-6 Bronchopulmonary dysplasia; TGCT cis rs9457247 0.967 rs2769346 chr6:167370999 A/G cg23791538 chr6:167370224 RNASET2 0.51 4.98 0.41 2.05e-6 Crohn's disease; TGCT cis rs62103177 0.789 rs7242289 chr18:77603291 C/T cg12964065 chr18:77638022 KCNG2 0.41 5.48 0.44 2.31e-7 Opioid sensitivity; TGCT cis rs11122272 0.735 rs2790889 chr1:231520240 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs6519955 0.897 rs4073601 chr22:46434686 A/G cg05468064 chr22:46423449 NA 0.58 6.22 0.49 6.97e-9 Dupuytren's disease; TGCT cis rs7267979 1.000 rs4815417 chr20:25379526 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2204008 0.571 rs1117803 chr12:38281007 C/G cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs6725041 0.792 rs1533768 chr2:213089875 T/A cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs904251 0.504 rs12202664 chr6:37481198 A/G cg25019722 chr6:37503610 NA -0.53 -7.98 -0.58 8.46e-13 Cognitive performance; TGCT cis rs7914558 0.901 rs1926034 chr10:104829102 G/A cg15744005 chr10:104629667 AS3MT -0.38 -4.66 -0.39 7.94e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6500602 0.893 rs6500596 chr16:4470027 G/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 5.29 0.43 5.42e-7 Schizophrenia; TGCT cis rs1887596 0.705 rs498498 chr13:27221206 G/A cg01312412 chr13:27282625 NA 0.28 4.91 0.4 2.87e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs919433 0.617 rs4850436 chr2:198541398 C/T cg00792783 chr2:198669748 PLCL1 -0.55 -5.04 -0.41 1.62e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs17539620 0.519 rs12665532 chr6:154835182 C/G cg20019720 chr6:154832845 CNKSR3 0.63 5.77 0.46 6.02e-8 Lipoprotein (a) levels; TGCT cis rs9486719 0.843 rs2499797 chr6:96848669 C/T cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT trans rs7618501 0.633 rs9866695 chr3:50069452 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.87 -9.71 -0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.76 -7.36 -0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs931608 0.640 rs2957824 chr19:22579316 T/C cg15554505 chr19:22123728 NA 0.63 4.89 0.4 3.06e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs11098499 0.697 rs10020027 chr4:120381879 G/C cg09307838 chr4:120376055 NA 0.71 6.98 0.53 1.57e-10 Corneal astigmatism; TGCT cis rs7681440 0.874 rs1372524 chr4:90776045 A/G cg14346243 chr4:90757452 SNCA -0.56 -5.47 -0.44 2.41e-7 Dementia with Lewy bodies; TGCT cis rs1218582 0.772 rs10908448 chr1:154882544 A/G cg06221963 chr1:154839813 KCNN3 0.73 11.91 0.73 2.91e-22 Prostate cancer; TGCT cis rs57221529 0.709 rs72703090 chr5:598314 C/T cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Lung disease severity in cystic fibrosis; TGCT cis rs1218582 0.741 rs7544528 chr1:154844585 C/T cg24250549 chr1:154909240 PMVK 0.53 4.89 0.4 3.05e-6 Prostate cancer; TGCT cis rs12681287 0.547 rs13260345 chr8:87483721 T/C cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs4733781 0.765 rs62524625 chr8:131084728 C/T cg16277922 chr8:131349729 ASAP1 0.39 4.94 0.41 2.42e-6 Tuberculosis; TGCT cis rs10114408 0.959 rs7853178 chr9:96648007 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2249625 0.526 rs17781511 chr6:72845455 C/T cg08500200 chr6:72892038 RIMS1 0.45 4.84 0.4 3.79e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs858239 0.539 rs10225608 chr7:23188908 A/G cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs1799949 0.965 rs8071278 chr17:41193910 A/T cg23758822 chr17:41437982 NA 0.66 6.44 0.5 2.36e-9 Menopause (age at onset); TGCT cis rs4455778 0.600 rs4282517 chr7:49115450 C/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs11098499 0.826 rs12511640 chr4:120251248 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs12510870 0.634 rs13120998 chr4:74378422 C/T cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs514406 0.861 rs4926932 chr1:53247495 C/T cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs881375 0.967 rs2239658 chr9:123671837 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.28 0.43 5.56e-7 Rheumatoid arthritis; TGCT cis rs2506155 0.585 rs72790215 chr10:33521398 G/C cg25928881 chr10:32632685 EPC1 0.3 4.98 0.41 2.05e-6 Migraine; TGCT cis rs763121 0.853 rs1065201 chr22:39069510 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs72781680 0.950 rs72796343 chr2:24147631 G/A cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs3916 0.955 rs2066938 chr12:121160615 A/G cg21892295 chr12:121157589 UNC119B -0.22 -4.51 -0.38 1.46e-5 Urinary metabolites (H-NMR features); TGCT cis rs1055129 0.682 rs7217432 chr17:73834604 A/G cg08125733 chr17:73851984 WBP2 0.51 4.65 0.39 8.21e-6 White matter hyperintensity burden; TGCT cis rs4927850 1.000 rs4927850 chr3:195751630 C/T cg22891161 chr3:195456627 MUC20 0.23 5.35 0.43 4.12e-7 Pancreatic cancer; TGCT cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs595982 0.559 rs17272680 chr19:49364511 A/G cg17863274 chr19:49399704 TULP2 0.46 6.54 0.51 1.46e-9 Red cell distribution width; TGCT cis rs4273100 0.688 rs4924967 chr17:19172196 T/G cg01534423 chr17:18965556 NA 0.79 7.13 0.54 7.34e-11 Schizophrenia; TGCT cis rs308403 0.532 rs309386 chr4:123665991 C/G cg10495464 chr4:123653540 BBS12;LOC729338 0.83 12.16 0.74 6.83e-23 Blood protein levels; TGCT cis rs17108533 0.588 rs12878094 chr14:71303542 A/G cg23900759 chr14:71108106 TTC9 -1.15 -4.79 -0.39 4.73e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs7208859 0.524 rs8069400 chr17:29075967 G/T cg13385521 chr17:29058706 SUZ12P 0.8 4.66 0.39 8.04e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17001868 0.568 rs12484697 chr22:40736472 A/G cg07138101 chr22:40742427 ADSL -0.73 -5.38 -0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs10504229 1.000 rs67096506 chr8:58195655 G/A cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs8177253 0.828 rs8177259 chr3:133480388 T/C cg11941060 chr3:133502564 NA -0.29 -6.16 -0.48 9.45e-9 Iron status biomarkers; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg26354017 chr1:205819088 PM20D1 0.56 6.86 0.52 2.9e-10 Menarche (age at onset); TGCT cis rs2456568 0.835 rs8181533 chr11:93638614 C/T cg16099599 chr11:93583650 C11orf90 -0.4 -5.12 -0.42 1.13e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6964587 0.967 rs6970743 chr7:91744311 C/G cg17063962 chr7:91808500 NA 0.89 9.53 0.65 1.78e-16 Breast cancer; TGCT cis rs2439831 1.000 rs7173487 chr15:43750239 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.98 7.06 0.54 1.07e-10 Lung cancer in ever smokers; TGCT cis rs3820928 0.934 rs16822890 chr2:227761477 G/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.68 -0.39 7.31e-6 Pulmonary function; TGCT cis rs12620999 0.555 rs4078064 chr2:238110296 C/T cg23555395 chr2:238036564 NA -0.27 -4.75 -0.39 5.57e-6 Systemic lupus erythematosus; TGCT cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Vitiligo; TGCT cis rs259991 0.661 rs236711 chr20:57694059 C/G cg01712452 chr20:56736072 C20orf85 -0.53 -4.61 -0.38 9.71e-6 Attention function in attention deficit hyperactive disorder; TGCT cis rs1008375 1.000 rs28545485 chr4:17645376 C/T cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11920354 0.642 rs9812878 chr3:47182787 T/C cg27129171 chr3:47204927 SETD2 0.67 7.67 0.57 4.3e-12 Granulocyte count;Sum neutrophil eosinophil counts; TGCT cis rs4918072 0.667 rs1342212 chr10:105708813 A/C cg11005552 chr10:105648138 OBFC1 0.34 4.74 0.39 5.86e-6 Coronary artery disease; TGCT cis rs7818688 0.697 rs76815619 chr8:95981330 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7119 0.717 rs12916515 chr15:77818518 G/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.59 -0.38 1.08e-5 Type 2 diabetes; TGCT cis rs13102973 0.965 rs13108037 chr4:135885643 A/G cg14419869 chr4:135874104 NA -0.25 -4.79 -0.39 4.71e-6 Subjective well-being; TGCT cis rs9467773 1.000 rs2393670 chr6:26535541 A/G cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs950169 0.845 rs4502182 chr15:84923520 A/G cg11189052 chr15:85197271 WDR73 0.83 6.67 0.51 7.71e-10 Schizophrenia; TGCT cis rs17102423 1.000 rs17102423 chr14:65604728 G/T cg11161011 chr14:65562177 MAX -0.49 -6.72 -0.52 5.81e-10 Obesity-related traits; TGCT trans rs1814175 0.645 rs11040702 chr11:50024827 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs11148252 0.538 rs9526842 chr13:52727723 T/G cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.85e-8 Lewy body disease; TGCT cis rs2046867 0.818 rs1502754 chr3:72895345 G/T cg25664220 chr3:72788482 NA -0.54 -5.82 -0.46 4.76e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs933688 1.000 rs332529 chr5:90789470 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 8.83 0.62 8.11e-15 Smoking behavior; TGCT cis rs763014 0.932 rs34498660 chr16:666149 A/G cg09263875 chr16:632152 PIGQ 0.31 6.88 0.53 2.65e-10 Height; TGCT cis rs651907 0.557 rs13077925 chr3:101488181 T/A cg12386194 chr3:101231763 SENP7 0.47 4.63 0.38 8.99e-6 Colorectal cancer; TGCT cis rs4888262 0.526 rs7193423 chr16:74626340 A/C cg05423758 chr16:74752063 FA2H 0.18 4.79 0.39 4.72e-6 Testicular germ cell tumor; TGCT cis rs9486715 1.000 rs9398148 chr6:97063555 A/G cg06623918 chr6:96969491 KIAA0776 -1.08 -13.52 -0.77 3.67e-26 Headache; TGCT cis rs68170813 0.559 rs17427123 chr7:106823661 G/A cg02696742 chr7:106810147 HBP1 -0.72 -6.28 -0.49 5.29e-9 Coronary artery disease; TGCT cis rs2663905 0.706 rs7162859 chr15:81360038 C/T cg09236163 chr15:81426669 C15orf26 0.6 5.61 0.45 1.27e-7 QT interval (drug interaction); TGCT cis rs7822232 0.908 rs1127096 chr8:145140472 A/G cg06495924 chr8:145149574 CYC1 -1.04 -4.49 -0.37 1.6e-5 Blood metabolite levels; TGCT cis rs7666738 0.791 rs2865958 chr4:99040732 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1635 0.826 rs3800327 chr6:28264928 G/C cg15743358 chr6:28303923 ZNF323 -1.36 -5.89 -0.47 3.47e-8 Schizophrenia; TGCT cis rs1975974 0.935 rs41361749 chr17:21732693 A/G cg18423549 chr17:21743878 NA 0.5 4.65 0.39 8.52e-6 Psoriasis; TGCT cis rs3784262 0.967 rs12148907 chr15:58296450 T/A cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.82 -0.57 1.98e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs919433 0.647 rs2045242 chr2:198507649 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.03 0.41 1.68e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs10206020 0.921 rs72778009 chr2:1573322 G/T cg12573674 chr2:1569213 NA -0.49 -5.3 -0.43 5.1e-7 IgG glycosylation; TGCT cis rs826838 0.967 rs2069211 chr12:39128892 C/T cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg05665937 chr4:1216051 CTBP1 0.24 4.63 0.38 8.9e-6 Obesity-related traits; TGCT cis rs1008375 0.966 rs4698621 chr4:17587565 C/T cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs259282 0.605 rs8100423 chr19:33109003 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.51 4.66 0.39 7.93e-6 Schizophrenia; TGCT cis rs2404602 0.735 rs2436996 chr15:76817420 C/T cg22467129 chr15:76604101 ETFA 0.47 4.88 0.4 3.19e-6 Blood metabolite levels; TGCT cis rs6426558 0.572 rs2670471 chr1:227454328 T/C cg10327440 chr1:227177885 CDC42BPA 0.58 6.76 0.52 4.75e-10 Neutrophil percentage of white cells; TGCT cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg13012494 chr21:47604986 C21orf56 0.36 4.5 0.37 1.54e-5 Testicular germ cell tumor; TGCT cis rs7980687 0.628 rs1609520 chr12:123735937 A/G cg00376283 chr12:123451042 ABCB9 -0.66 -5.35 -0.43 4.08e-7 Height;Educational attainment;Head circumference (infant); TGCT cis rs7572733 0.555 rs1435569 chr2:198718667 G/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg06481639 chr22:41940642 POLR3H 0.74 6.55 0.51 1.41e-9 Vitiligo; TGCT cis rs611744 0.967 rs695028 chr8:109239324 T/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs2836974 0.568 rs11910906 chr21:40685662 T/C cg11890956 chr21:40555474 PSMG1 -0.76 -7.08 -0.54 9.53e-11 Cognitive function; TGCT cis rs9346649 0.967 rs6920748 chr6:168490047 T/G cg02770688 chr6:168491649 NA -0.27 -5.08 -0.41 1.36e-6 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs950169 0.922 rs62021167 chr15:85118051 T/A cg11189052 chr15:85197271 WDR73 0.78 6.5 0.5 1.77e-9 Schizophrenia; TGCT cis rs12497850 0.865 rs13072911 chr3:48962128 T/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs13191362 1.000 rs35593345 chr6:163174981 G/C cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.77 0.52 4.6e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs7618501 1.000 rs1491986 chr3:49739086 C/T cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs854765 0.583 rs4077198 chr17:17834563 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs6121246 0.567 rs2889488 chr20:30185758 G/A cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.42e-6 Mean corpuscular hemoglobin; TGCT cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs8017423 0.967 rs11159957 chr14:90715972 A/G cg04374321 chr14:90722782 PSMC1 -0.72 -7.54 -0.56 8.86e-12 Mortality in heart failure; TGCT cis rs75686122 0.892 rs75117899 chr8:104582618 A/G cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg14159672 chr1:205819179 PM20D1 -0.57 -7.12 -0.54 7.6e-11 Menarche (age at onset); TGCT cis rs2204008 0.805 rs10881112 chr12:37956611 G/A cg26384229 chr12:38710491 ALG10B -0.73 -6.26 -0.49 5.88e-9 Bladder cancer; TGCT cis rs9467711 0.651 rs35378061 chr6:26059157 C/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.6 -4.67 -0.39 7.83e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1534166 0.647 rs13321680 chr3:133507119 G/T cg08048268 chr3:133502702 NA 0.45 5.54 0.45 1.7e-7 Alcohol consumption (transferrin glycosylation); TGCT cis rs72615157 0.634 rs11762932 chr7:99792666 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 -0.64 -5.12 -0.42 1.15e-6 Lung function (FEV1/FVC); TGCT cis rs736408 0.736 rs4687550 chr3:52823430 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.94 -0.41 2.52e-6 Bipolar disorder; TGCT cis rs2404602 0.647 rs11072625 chr15:77084984 A/G cg22467129 chr15:76604101 ETFA -0.49 -5.08 -0.42 1.32e-6 Blood metabolite levels; TGCT cis rs6840360 1.000 rs6535810 chr4:152592953 C/T cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.33e-7 Intelligence (multi-trait analysis); TGCT cis rs1198872 0.526 rs57282335 chr2:10928207 G/A cg15705551 chr2:10952987 PDIA6 0.55 4.81 0.4 4.38e-6 Cardiac Troponin-T levels; TGCT cis rs4819052 0.851 rs9974891 chr21:46680767 T/A cg06618935 chr21:46677482 NA -0.36 -5.5 -0.44 2.06e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.861 rs13139309 chr4:99020916 A/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3796352 1.000 rs34121720 chr3:53072167 C/T cg27565382 chr3:53032988 SFMBT1 0.43 4.62 0.38 9.64e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7949030 0.626 rs71490390 chr11:62329185 A/G cg22862634 chr11:62369728 EML3;MTA2 0.71 9.07 0.63 2.23e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2153535 0.526 rs7748404 chr6:8472500 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs250677 0.687 rs36043 chr5:148440983 G/A cg18129178 chr5:148520854 ABLIM3 -0.44 -6.57 -0.51 1.27e-9 Breast cancer; TGCT cis rs9308731 0.644 rs7577824 chr2:111876763 G/A cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.1e-9 Chronic lymphocytic leukemia; TGCT cis rs9534288 0.797 rs7990238 chr13:46578379 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg22963979 chr7:1858916 MAD1L1 -0.46 -7.65 -0.57 4.73e-12 Bipolar disorder and schizophrenia; TGCT cis rs854572 1.000 rs854572 chr7:94954696 C/G cg01874867 chr7:94954059 PON1 -0.4 -5.85 -0.47 4.06e-8 Paraoxonase activity; TGCT cis rs929596 0.755 rs3771341 chr2:234673239 G/A cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.35 -5.68 -0.45 9.25e-8 Total bilirubin levels in HIV-1 infection; TGCT cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg22168489 chr12:122356033 WDR66 0.2 4.74 0.39 5.87e-6 Mean corpuscular volume; TGCT cis rs9527 0.590 rs12415199 chr10:104895536 T/C cg04362960 chr10:104952993 NT5C2 0.69 5.82 0.46 4.78e-8 Arsenic metabolism; TGCT cis rs9581857 0.547 rs4612914 chr13:28049128 A/G cg22138327 chr13:27999177 GTF3A 0.77 5.12 0.42 1.16e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs67385638 0.792 rs16912979 chr11:5309695 T/C cg12559170 chr11:5275217 HBG2 0.42 7.33 0.55 2.57e-11 Hemoglobin levels; TGCT cis rs17102423 0.685 rs7156617 chr14:65541381 G/A cg11161011 chr14:65562177 MAX -0.51 -7.28 -0.55 3.3e-11 Obesity-related traits; TGCT cis rs5750830 0.649 rs4384886 chr22:39793766 C/T cg01416388 chr22:39784598 NA -0.73 -7.54 -0.56 8.5e-12 Intelligence (multi-trait analysis); TGCT trans rs1005277 0.579 rs1780139 chr10:38503018 C/T cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs6815814 0.950 rs66922907 chr4:38812537 A/G cg02016764 chr4:38805732 TLR1 -0.36 -5.67 -0.45 9.33e-8 Breast cancer; TGCT cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs11578119 0.689 rs1591148 chr1:170386703 G/T cg09767346 chr1:170501363 GORAB -0.6 -4.97 -0.41 2.2e-6 Male-pattern baldness; TGCT cis rs7917772 0.636 rs2253709 chr10:104542745 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.58 4.73 0.39 6.1e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs71435601 0.628 rs533211 chr2:21381702 G/A cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs7208859 0.623 rs58908911 chr17:29244558 C/T cg14008862 chr17:28927542 LRRC37B2 0.73 4.8 0.4 4.43e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs514406 0.505 rs437954 chr1:53173321 C/G cg08859206 chr1:53392774 SCP2 -0.35 -4.98 -0.41 2.12e-6 Monocyte count; TGCT cis rs2404602 0.647 rs10851892 chr15:77176491 T/C cg22467129 chr15:76604101 ETFA 0.47 4.79 0.4 4.69e-6 Blood metabolite levels; TGCT cis rs9926296 0.618 rs8058179 chr16:89846987 C/T cg27121462 chr16:89883253 FANCA -0.55 -5.05 -0.41 1.52e-6 Vitiligo; TGCT cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.17 -0.42 9.08e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs514406 0.861 rs6588443 chr1:53250650 G/A cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs2594989 1.000 rs2606747 chr3:11374955 T/C cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs73198271 0.740 rs28521727 chr8:8647217 T/C cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs881375 0.967 rs2109895 chr9:123677827 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 5.02 0.41 1.74e-6 Rheumatoid arthritis; TGCT cis rs877282 0.733 rs7092976 chr10:756358 G/A cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs116095464 0.614 rs10067482 chr5:219328 T/G cg22857025 chr5:266934 NA -0.31 -6.36 -0.5 3.45e-9 Breast cancer; TGCT cis rs861020 0.630 rs9308411 chr1:210005713 C/T cg05527609 chr1:210001259 C1orf107 0.86 7.9 0.58 1.28e-12 Orofacial clefts; TGCT cis rs13272623 0.502 rs268599 chr8:71517401 G/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.58 -5.1 -0.42 1.23e-6 IgG glycosylation; TGCT cis rs589448 0.902 rs2603089 chr12:69776800 C/T cg14784868 chr12:69753453 YEATS4 -0.9 -10.6 -0.69 4.47e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs916888 0.647 rs199524 chr17:44848438 G/T cg01570182 chr17:44337453 NA -0.84 -8.15 -0.59 3.41e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7666738 0.830 rs114722517 chr4:99042061 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg17345569 chr6:42928274 GNMT -0.47 -4.86 -0.4 3.48e-6 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs12599106 0.839 rs3853177 chr16:34498532 A/G cg01516881 chr6:292596 DUSP22 -0.71 -7.6 -0.56 6.19e-12 Menopause (age at onset); TGCT cis rs6671200 0.607 rs1927043 chr1:95667251 G/A cg20701556 chr1:95698924 RWDD3 -0.54 -5.36 -0.43 3.98e-7 Stearic acid (18:0) levels; TGCT cis rs61990749 0.597 rs1006039 chr14:78263196 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.63 -4.46 -0.37 1.8e-5 Fibroblast growth factor basic levels; TGCT cis rs9467711 0.606 rs12173854 chr6:26371679 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.679 rs960570 chr1:53237763 A/G cg01802117 chr1:53393560 SCP2 0.49 6.02 0.48 1.86e-8 Monocyte count; TGCT cis rs9393692 0.902 rs6456711 chr6:26302572 A/C cg05868516 chr6:26286170 HIST1H4H 0.62 5.85 0.46 4.17e-8 Educational attainment; TGCT cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT trans rs2727020 0.729 rs1164685 chr11:49293660 G/A cg03929089 chr4:120376271 NA 0.73 8.5 0.61 4.94e-14 Coronary artery disease; TGCT cis rs9435341 0.826 rs17496332 chr1:107546375 C/T cg09367891 chr1:107599246 PRMT6 -0.63 -5.47 -0.44 2.35e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs10464366 0.560 rs11763728 chr7:39145862 C/T cg15212455 chr7:39170539 POU6F2 0.23 5.24 0.43 6.54e-7 IgG glycosylation; TGCT cis rs7659604 0.676 rs4516739 chr4:122699741 G/T cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.63 -0.45 1.15e-7 Type 2 diabetes; TGCT cis rs10782582 0.609 rs1770889 chr1:76401166 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.46 0.37 1.83e-5 Daytime sleep phenotypes; TGCT cis rs7647973 1.000 rs6446275 chr3:49466871 A/G cg06212747 chr3:49208901 KLHDC8B -0.57 -4.56 -0.38 1.21e-5 Menarche (age at onset); TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg25767906 chr1:53392781 SCP2 -0.58 -7.3 -0.55 3.08e-11 Monocyte count; TGCT cis rs26868 0.816 rs26873 chr16:2247362 C/T cg02248941 chr16:2239361 CASKIN1 0.17 4.48 0.37 1.69e-5 Height; TGCT cis rs3741151 1.000 rs78433080 chr11:73067565 G/A cg17517138 chr11:73019481 ARHGEF17 0.91 4.63 0.38 9e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs6540559 0.673 rs6540561 chr1:209982255 C/T cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs6459680 0.583 rs6957065 chr7:156268046 G/A cg02321112 chr7:156810523 NA -0.31 -4.65 -0.39 8.2e-6 Glomerular filtration rate (creatinine); TGCT cis rs151997 1.000 rs152817 chr5:50230879 T/A cg06027927 chr5:50259733 NA -0.47 -4.86 -0.4 3.47e-6 Callous-unemotional behaviour; TGCT cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs7582180 0.629 rs7597615 chr2:100954828 T/C cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs854765 0.547 rs4368210 chr17:17896090 A/G cg04398451 chr17:18023971 MYO15A 0.32 5.15 0.42 1.01e-6 Total body bone mineral density; TGCT cis rs4742903 1.000 rs3780535 chr9:106894211 A/C cg21169611 chr9:106856078 SMC2 0.51 4.84 0.4 3.81e-6 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs12788102 0.522 rs1865282 chr11:4830652 A/C cg17625643 chr11:3845204 PGAP2 0.22 4.45 0.37 1.9e-5 Malaria; TGCT cis rs7772486 0.754 rs4896832 chr6:145964151 G/A cg13319975 chr6:146136371 FBXO30 -0.53 -4.85 -0.4 3.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT trans rs7726839 0.540 rs58599998 chr5:596087 A/G cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs3796352 1.000 rs10510761 chr3:52965255 A/G cg07884673 chr3:53033167 SFMBT1 -0.63 -6.1 -0.48 1.23e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs76878669 0.561 rs905770 chr11:66156765 A/G cg18002602 chr11:66138449 SLC29A2 0.53 6.54 0.51 1.43e-9 Educational attainment (years of education); TGCT cis rs2456568 0.835 rs7936182 chr11:93665532 T/A cg17595323 chr11:93583763 C11orf90 -0.46 -5.86 -0.47 3.97e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs8033133 0.581 rs8042796 chr15:25327396 A/C cg14481604 chr15:25334117 SNORD116-22 -0.21 -4.64 -0.38 8.82e-6 Blood osmolality (transformed sodium); TGCT cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg18252515 chr7:66147081 NA -1.26 -7.23 -0.54 4.43e-11 Diabetic kidney disease; TGCT cis rs75686122 0.892 rs117473860 chr8:104710816 C/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7659604 0.643 rs6839375 chr4:122663610 G/C cg06713675 chr4:122721982 EXOSC9 -0.45 -5.24 -0.43 6.75e-7 Type 2 diabetes; TGCT cis rs7312933 0.558 rs11181467 chr12:42765250 C/T cg19980929 chr12:42632907 YAF2 0.43 6.03 0.48 1.79e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs35306767 0.903 rs11253485 chr10:919362 C/T cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs7552404 0.731 rs931507 chr1:76401577 G/A cg03433033 chr1:76189801 ACADM -0.74 -7.49 -0.56 1.14e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg08048268 chr3:133502702 NA -0.54 -7.2 -0.54 5.06e-11 Iron status biomarkers; TGCT cis rs36051895 0.622 rs12335546 chr9:5072182 C/T cg02405213 chr9:5042618 JAK2 -0.85 -12.71 -0.75 3.36e-24 Pediatric autoimmune diseases; TGCT cis rs6684514 1.000 rs12038203 chr1:156248265 C/T cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs631288 0.557 rs7546434 chr1:146676339 A/G cg25205988 chr1:146714368 CHD1L 1.33 5.42 0.44 2.97e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs7659604 0.521 rs4833235 chr4:122695136 C/A cg06713675 chr4:122721982 EXOSC9 0.35 4.48 0.37 1.64e-5 Type 2 diabetes; TGCT trans rs6089829 0.926 rs6011552 chr20:61667894 T/C cg23505145 chr19:12996616 KLF1 0.8 8.37 0.6 1.05e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs9858542 1.000 rs9882740 chr3:49702484 T/C cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs11098499 0.954 rs11940028 chr4:120411907 T/C cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs6089829 0.962 rs6089825 chr20:61668447 C/T cg18188782 chr20:61659543 NA 0.46 5.61 0.45 1.23e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs1005277 0.579 rs2474571 chr10:38384639 T/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.22 -0.59 2.3e-13 Extrinsic epigenetic age acceleration; TGCT cis rs317689 0.819 rs317660 chr12:69686203 G/A cg14784868 chr12:69753453 YEATS4 0.57 4.9 0.4 2.96e-6 Response to diuretic therapy; TGCT cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.03 -0.76 5.66e-25 Vitiligo; TGCT cis rs7511006 0.893 rs2038049 chr22:50654888 G/C cg08875078 chr22:50639485 SELO 0.53 5.05 0.41 1.51e-6 Obesity-related traits; TGCT cis rs6570726 0.791 rs7765687 chr6:145915100 A/C cg05347473 chr6:146136440 FBXO30 0.51 4.74 0.39 5.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6429082 0.818 rs704706 chr1:235614378 G/A cg26050004 chr1:235667680 B3GALNT2 0.58 4.98 0.41 2.08e-6 Adiposity; TGCT cis rs4700695 0.614 rs40194 chr5:65219842 G/A cg21114390 chr5:65439923 SFRS12 0.65 4.54 0.38 1.3e-5 Facial morphology (factor 19); TGCT cis rs17102423 0.559 rs11624169 chr14:65481710 C/G cg11161011 chr14:65562177 MAX -0.46 -5.33 -0.43 4.45e-7 Obesity-related traits; TGCT cis rs3733585 0.638 rs17185835 chr4:9958180 T/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.71e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2637266 1.000 rs12260379 chr10:78365036 C/T cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs2032447 0.898 rs807205 chr6:26075035 C/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.6 -5.9 -0.47 3.28e-8 Intelligence (multi-trait analysis); TGCT cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg08439880 chr3:133502540 NA -0.26 -4.69 -0.39 7.05e-6 Iron status biomarkers; TGCT cis rs7666738 0.830 rs1115616 chr4:99006603 A/C cg18180107 chr4:99064573 C4orf37 0.54 4.98 0.41 2.1e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs7618501 0.633 rs6446189 chr3:50008566 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.9 0.66 2.18e-17 Intelligence (multi-trait analysis); TGCT cis rs1451375 0.698 rs11489734 chr7:50635730 A/T cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg12751644 chr20:60527061 NA -0.4 -4.63 -0.38 9.23e-6 Body mass index; TGCT cis rs77972916 0.561 rs4372955 chr2:43566146 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -5.03 -0.41 1.66e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4727027 0.901 rs12671341 chr7:148805282 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.6 0.38 1.04e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg02953382 chr22:24373134 LOC391322 -0.81 -8.91 -0.62 5.26e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4455778 0.580 rs6583501 chr7:49077636 A/T cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.07e-9 Lung cancer in never smokers; TGCT cis rs7264396 0.528 rs7273880 chr20:34551507 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs17401966 0.540 rs3748581 chr1:10441664 T/C cg19773385 chr1:10388646 KIF1B -0.22 -5.27 -0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg10263370 chr3:44754102 ZNF502 -0.44 -5.23 -0.42 7.06e-7 Depressive symptoms; TGCT cis rs7267979 0.966 rs7270835 chr20:25435067 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9457247 0.534 rs933243 chr6:167403873 A/C cg23791538 chr6:167370224 RNASET2 -0.58 -5.76 -0.46 6.13e-8 Crohn's disease; TGCT cis rs68092024 0.731 rs792841 chr3:99471308 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 6.19 0.49 8.23e-9 Cleft lip with or without cleft palate; TGCT cis rs7726839 0.574 rs11134149 chr5:637277 A/G cg20362242 chr5:692897 TPPP 0.49 4.81 0.4 4.21e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs13145011 chr4:98993410 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7027203 0.576 rs7855940 chr9:96535966 C/G cg14598338 chr9:96623480 NA -0.48 -6.99 -0.53 1.54e-10 DNA methylation (variation); TGCT cis rs492146 0.729 rs316130 chr6:52848200 G/A cg06706454 chr6:52930286 FBXO9 -0.53 -4.95 -0.41 2.37e-6 Epilepsy (remission after treatment); TGCT cis rs826838 0.935 rs1684407 chr12:39127270 C/T cg26384229 chr12:38710491 ALG10B -0.86 -7.72 -0.57 3.37e-12 Heart rate; TGCT cis rs4889911 0.544 rs1285273 chr17:77830885 A/G cg00646381 chr17:77835854 NA 0.44 6.6 0.51 1.06e-9 Electroencephalogram traits; TGCT cis rs910316 1.000 rs4903289 chr14:75623988 C/T cg23033748 chr14:75592666 NEK9 -0.29 -4.84 -0.4 3.86e-6 Height; TGCT cis rs6089829 0.889 rs6062773 chr20:61663262 G/C cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs2742234 0.759 rs12241923 chr10:43713047 T/C cg02780029 chr10:43622663 RET 0.26 5.04 0.41 1.58e-6 Hirschsprung disease; TGCT cis rs7666738 0.830 rs35644814 chr4:98886111 G/C cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.81e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs114916728 chr4:119776886 G/A cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs7267979 1.000 rs448396 chr20:25440269 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611519 1.000 rs5758267 chr22:41619350 A/T cg03806693 chr22:41940476 POLR3H 0.67 6.4 0.5 2.94e-9 Neuroticism; TGCT cis rs6860806 0.507 rs635619 chr5:131720265 G/A cg24060327 chr5:131705240 SLC22A5 0.77 8.48 0.61 5.57e-14 Breast cancer; TGCT trans rs9859260 0.744 rs406271 chr3:195776976 T/C cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs7829975 0.774 rs35039922 chr8:8675325 A/T cg06636001 chr8:8085503 FLJ10661 0.66 5.78 0.46 5.66e-8 Mood instability; TGCT cis rs2204008 0.594 rs11531211 chr12:37998007 T/G cg26384229 chr12:38710491 ALG10B -0.7 -6.1 -0.48 1.27e-8 Bladder cancer; TGCT cis rs11874712 0.932 rs8092674 chr18:43665982 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs7043114 0.525 rs710162 chr9:95059790 A/T cg14631576 chr9:95140430 CENPP 0.29 4.7 0.39 6.71e-6 Height; TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs597539 0.615 rs583182 chr11:68678634 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 7.99 0.58 8.01e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10466239 0.730 rs2243492 chr10:43849358 C/T cg12891252 chr10:43902500 HNRNPF -0.69 -4.55 -0.38 1.28e-5 Telomere length; TGCT cis rs1008375 1.000 rs28497813 chr4:17685503 A/G cg18681998 chr4:17616180 MED28 0.92 10.51 0.69 7.15e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10791097 0.694 rs2236711 chr11:130739284 G/A cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9372253 0.818 rs2207360 chr6:110706337 G/C cg00083206 chr6:110721305 DDO -0.36 -5.22 -0.42 7.19e-7 Platelet distribution width; TGCT cis rs17376456 0.877 rs13156865 chr5:93390908 C/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT trans rs941408 1.000 rs1640274 chr19:2807375 G/A cg19676328 chr12:49525230 TUBA1B -0.87 -7.92 -0.58 1.13e-12 Total cholesterol levels; TGCT cis rs34638657 0.500 rs12446210 chr16:82185762 G/A cg09439754 chr16:82129088 HSD17B2 -0.23 -4.8 -0.4 4.55e-6 Lung adenocarcinoma; TGCT cis rs2562456 0.682 rs11085464 chr19:21751778 C/G cg25650185 chr19:21324782 ZNF431 -0.66 -5.85 -0.46 4.18e-8 Pain; TGCT cis rs597539 0.652 rs553875 chr11:68695144 T/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.79 7.22 0.54 4.57e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs875971 0.660 rs28698552 chr7:66005018 A/G cg18876405 chr7:65276391 NA 0.37 5.58 0.45 1.47e-7 Aortic root size; TGCT cis rs9810089 0.814 rs1279424 chr3:136007333 A/G cg12473912 chr3:136751656 NA 0.35 4.91 0.4 2.77e-6 Gestational age at birth (child effect); TGCT cis rs7666738 0.830 rs17027058 chr4:98864671 G/A cg05340658 chr4:99064831 C4orf37 0.52 6.03 0.48 1.78e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs694739 0.657 rs11231770 chr11:64140625 G/A cg02228329 chr11:64053129 BAD;GPR137 0.7 6.8 0.52 4.02e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs6426558 0.502 rs2813965 chr1:227445733 A/G cg10327440 chr1:227177885 CDC42BPA 0.58 6.76 0.52 4.75e-10 Neutrophil percentage of white cells; TGCT cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.501 rs11692336 chr2:99740606 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs1008375 0.863 rs10003291 chr4:17600728 A/C cg10189774 chr4:17578691 LAP3 0.62 4.99 0.41 2e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6121246 0.821 rs6121209 chr20:30311258 G/C cg10886678 chr20:30946050 ASXL1 -0.62 -4.5 -0.37 1.54e-5 Mean corpuscular hemoglobin; TGCT cis rs11264213 0.901 rs72661646 chr1:36454954 A/T cg27506609 chr1:36549197 TEKT2 0.41 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs1580019 0.587 rs2392069 chr7:32547154 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.96 0.41 2.25e-6 Cognitive ability; TGCT cis rs79349575 0.783 rs12453374 chr17:46994846 G/C cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs6840360 0.515 rs11099811 chr4:152320532 C/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.68e-9 Intelligence (multi-trait analysis); TGCT cis rs12049351 0.719 rs6587338 chr1:229632638 G/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs265548 0.586 rs265542 chr19:17904388 T/G cg16744531 chr19:17905626 B3GNT3 0.41 5.03 0.41 1.69e-6 Tumor biomarkers; TGCT cis rs11085466 0.948 rs76881507 chr19:21762189 A/T cg23026602 chr19:21646605 NA -0.57 -4.59 -0.38 1.05e-5 Colorectal or endometrial cancer; TGCT cis rs11249608 0.548 rs7709054 chr5:178462757 C/T cg01312482 chr5:178451176 ZNF879 -0.49 -4.83 -0.4 3.96e-6 Pubertal anthropometrics; TGCT cis rs453301 0.658 rs6983877 chr8:8904639 T/C cg08975724 chr8:8085496 FLJ10661 -0.54 -4.46 -0.37 1.8e-5 Joint mobility (Beighton score); TGCT cis rs40363 1.000 rs1690444 chr16:3518350 G/A cg22508957 chr16:3507546 NAT15 0.57 5.29 0.43 5.31e-7 Tuberculosis; TGCT cis rs2115630 0.641 rs11073613 chr15:85185893 G/A cg17173187 chr15:85201210 NMB -0.38 -4.69 -0.39 7.04e-6 P wave terminal force; TGCT cis rs3125734 0.572 rs3864794 chr10:64041956 A/C cg09941381 chr10:64027924 RTKN2 -0.33 -4.91 -0.4 2.76e-6 Rheumatoid arthritis; TGCT cis rs7523050 0.730 rs12079547 chr1:109469314 A/C cg08274380 chr1:109419600 GPSM2 1.29 6.93 0.53 2.02e-10 Fat distribution (HIV); TGCT cis rs9611565 0.500 rs10775759 chr22:42088158 T/C cg06634786 chr22:41940651 POLR3H 0.9 9.03 0.63 2.7e-15 Vitiligo; TGCT cis rs11190604 0.747 rs11190516 chr10:102173525 G/A cg16005271 chr10:102321736 NA 0.45 4.57 0.38 1.15e-5 Palmitoleic acid (16:1n-7) levels; TGCT trans rs7819412 0.715 rs2409727 chr8:11043236 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.66 -0.51 7.84e-10 Triglycerides; TGCT cis rs10507380 0.824 rs80030408 chr13:27919648 C/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs7824557 0.564 rs2736300 chr8:11235579 T/G cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.95e-9 Retinal vascular caliber; TGCT cis rs9911578 1.000 rs7216680 chr17:56988243 G/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs4820539 0.933 rs2267004 chr22:23459863 G/A cg21100191 chr22:23484243 RTDR1 0.93 10.72 0.69 2.21e-19 Bone mineral density; TGCT cis rs11190604 1.000 rs7078799 chr10:102301447 G/A cg23241863 chr10:102295624 HIF1AN 0.69 5.1 0.42 1.26e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs853679 0.517 rs2273564 chr6:28057594 A/T cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs35160687 0.901 rs35762338 chr2:86513553 G/A cg03171300 chr2:86307199 POLR1A 0.32 5.54 0.45 1.73e-7 Night sleep phenotypes; TGCT cis rs4786125 0.542 rs2345826 chr16:6916235 G/T cg03623568 chr16:6915990 A2BP1 -0.44 -6.55 -0.51 1.38e-9 Heart rate variability traits (SDNN); TGCT cis rs6125597 0.935 rs6067034 chr20:47900164 G/A cg11220565 chr20:47934802 NA -0.3 -4.61 -0.38 9.77e-6 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs12295885 chr11:50036762 T/G cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs6076065 0.748 rs2253834 chr20:23387816 C/T cg11657817 chr20:23433608 CST11 -0.29 -5.15 -0.42 1.01e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg27286337 chr10:134555280 INPP5A 0.37 4.52 0.38 1.4e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4654899 1.000 rs7537072 chr1:21434533 T/C cg01072550 chr1:21505969 NA -0.51 -8.27 -0.6 1.76e-13 Superior frontal gyrus grey matter volume; TGCT cis rs9911578 1.000 rs4636974 chr17:56965373 C/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.754 rs4707374 chr6:88255438 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs2688608 0.592 rs3933085 chr10:75483331 C/T cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg13395646 chr4:1353034 KIAA1530 -0.39 -4.96 -0.41 2.3e-6 Obesity-related traits; TGCT cis rs2456568 0.802 rs1574515 chr11:93629643 T/C cg14065697 chr11:93583672 C11orf90 -0.37 -4.64 -0.38 8.58e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7208859 0.573 rs11656278 chr17:29075188 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6912958 0.712 rs6930600 chr6:88349787 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs7664169 chr4:99037859 C/T cg05340658 chr4:99064831 C4orf37 -0.49 -5.52 -0.44 1.93e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3902035 0.964 rs62422254 chr6:119004249 A/T cg07617317 chr6:118971624 C6orf204 0.43 5.08 0.41 1.37e-6 QT interval; TGCT cis rs9399135 1.000 rs6569988 chr6:135352303 C/A cg24558204 chr6:135376177 HBS1L 0.48 4.83 0.4 3.88e-6 Red blood cell count; TGCT cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs1008375 1.000 rs3815413 chr4:17654648 T/C cg10189774 chr4:17578691 LAP3 0.6 5.29 0.43 5.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2721195 0.845 rs3816732 chr8:145724275 T/C cg15320075 chr8:145703422 NA 0.69 6.73 0.52 5.6e-10 Age at first birth; TGCT cis rs1801239 1.000 rs78625146 chr10:16933839 T/A cg00939682 chr10:16933505 CUBN 0.48 4.49 0.37 1.59e-5 Urinary albumin-to-creatinine ratio in non-diabetics;Urinary albumin excretion; TGCT cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg09323728 chr8:95962352 TP53INP1 -0.49 -6.29 -0.49 4.86e-9 Type 2 diabetes; TGCT cis rs7617773 0.778 rs11707997 chr3:48377875 A/G cg11946769 chr3:48343235 NME6 0.82 6.99 0.53 1.49e-10 Coronary artery disease; TGCT cis rs1971762 0.545 rs10783586 chr12:53980821 C/T cg16917193 chr12:54089295 NA 0.93 9.72 0.66 5.91e-17 Height; TGCT cis rs2115630 0.691 rs2292462 chr15:85200754 G/T cg17173187 chr15:85201210 NMB -0.47 -5.72 -0.46 7.45e-8 P wave terminal force; TGCT cis rs4730250 0.669 rs6466160 chr7:106793175 T/A cg02696742 chr7:106810147 HBP1 0.72 5.89 0.47 3.44e-8 Osteoarthritis; TGCT trans rs208520 0.770 rs2153941 chr6:66885521 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -10.37 -0.68 1.58e-18 Exhaled nitric oxide output; TGCT cis rs7666738 0.611 rs34982650 chr4:98819530 T/A cg05340658 chr4:99064831 C4orf37 0.51 6.03 0.48 1.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs735396 0.770 rs1169314 chr12:121443116 A/G cg02403541 chr12:121454288 C12orf43 0.76 7.38 0.55 2.05e-11 N-glycan levels; TGCT cis rs4665809 1.000 rs4665306 chr2:26319124 C/T cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs7635838 0.892 rs9870881 chr3:11447082 A/G cg00170343 chr3:11313890 ATG7 0.65 6.15 0.48 9.98e-9 HDL cholesterol; TGCT trans rs931812 1.000 rs4734495 chr8:101917817 C/A cg20993868 chr7:22813445 NA 0.36 8.02 0.58 6.78e-13 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs514406 0.679 rs960570 chr1:53237763 A/G cg22166914 chr1:53195759 ZYG11B -0.36 -5.93 -0.47 2.78e-8 Monocyte count; TGCT cis rs60843830 1.000 rs2126129 chr2:212548 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.71 6.4 0.5 2.83e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs514406 0.505 rs416968 chr1:53183513 A/G cg22166914 chr1:53195759 ZYG11B 0.44 7.85 0.58 1.67e-12 Monocyte count; TGCT cis rs4595586 0.545 rs7976609 chr12:39394317 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs11250098 0.583 rs7001456 chr8:10804865 C/G cg21775007 chr8:11205619 TDH -0.56 -5.09 -0.42 1.3e-6 Morning vs. evening chronotype; TGCT trans rs4957048 0.891 rs11960196 chr5:568857 C/A cg11887960 chr12:57824829 NA 1.02 7.74 0.57 3.07e-12 Ulcerative colitis; TGCT cis rs6674176 1.000 rs6674176 chr1:44379957 G/A cg13606994 chr1:44402422 ARTN -0.46 -4.71 -0.39 6.45e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg08219700 chr8:58056026 NA 0.38 4.61 0.38 1e-5 Developmental language disorder (linguistic errors); TGCT cis rs1406084 0.541 rs1822208 chr2:154630981 C/G cg25703346 chr2:154729189 GALNT13 0.91 4.49 0.37 1.59e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs473651 0.935 rs541128 chr2:239336449 A/G cg18131467 chr2:239335373 ASB1 1.02 15.09 0.8 7.51e-30 Multiple system atrophy; TGCT cis rs7192750 0.539 rs7193731 chr16:71897399 T/C cg06353428 chr16:71660113 MARVELD3 0.83 7.37 0.55 2.07e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7226408 0.857 rs11664715 chr18:34435068 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6570726 0.791 rs405206 chr6:145836873 C/A cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9388451 0.839 rs11154331 chr6:126111429 A/T cg05901451 chr6:126070800 HEY2 -1.0 -14.26 -0.79 6.67e-28 Brugada syndrome; TGCT cis rs34014631 0.892 rs7919455 chr10:103689176 T/C cg22630918 chr10:102748988 C10orf2 0.42 4.78 0.39 4.86e-6 Coronary artery calcification; TGCT cis rs78487399 0.710 rs75514072 chr2:43750224 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg06969265 chr17:73775802 H3F3B 0.65 4.6 0.38 1.03e-5 Psoriasis; TGCT cis rs28595532 0.925 rs28627331 chr4:119665345 T/C cg11846333 chr4:119757529 SEC24D 0.95 4.9 0.4 2.97e-6 Cannabis dependence symptom count; TGCT cis rs926938 1.000 rs926938 chr1:115239816 A/G cg12756093 chr1:115239321 AMPD1 -0.48 -6.78 -0.52 4.36e-10 Autism; TGCT cis rs2153535 0.580 rs6912193 chr6:8456306 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7666738 0.830 rs3846443 chr4:99032666 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2842992 0.789 rs4235925 chr6:160202860 C/T cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs7666738 0.830 rs1426670 chr4:98923572 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6543140 0.855 rs4851591 chr2:103077423 T/C cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs1153858 1.000 rs56806728 chr15:45637814 A/G cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT trans rs7819412 0.875 rs6981523 chr8:11061792 C/T cg15556689 chr8:8085844 FLJ10661 -0.78 -7.71 -0.57 3.6e-12 Triglycerides; TGCT cis rs9910055 0.529 rs190144 chr17:42164584 A/G cg19774624 chr17:42201019 HDAC5 0.69 6.13 0.48 1.05e-8 Total body bone mineral density; TGCT cis rs2797160 1.000 rs1954361 chr6:126001423 C/G cg05901451 chr6:126070800 HEY2 -0.73 -6.27 -0.49 5.51e-9 Endometrial cancer; TGCT cis rs10858047 0.883 rs72698008 chr1:115086264 A/G cg12756093 chr1:115239321 AMPD1 0.45 4.63 0.38 9.24e-6 Autism; TGCT cis rs2839186 0.786 rs7409792 chr21:47691729 C/A cg13732083 chr21:47605072 C21orf56 0.35 4.64 0.38 8.64e-6 Testicular germ cell tumor; TGCT cis rs422249 0.819 rs174611 chr11:61627881 T/C cg19610905 chr11:61596333 FADS2 -0.63 -4.84 -0.4 3.71e-6 Trans fatty acid levels; TGCT cis rs6964587 1.000 rs17164263 chr7:91581566 T/A cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs9443645 0.901 rs56057971 chr6:79607182 G/A cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT trans rs2610739 0.554 rs9353573 chr6:89223517 G/C cg05764691 chr16:22927585 HS3ST2 0.4 6.62 0.51 9.76e-10 IgG glycosylation; TGCT cis rs9911578 1.000 rs7207693 chr17:57016525 C/T cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs586238 chr11:95560371 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.99 0.63 3.53e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7617773 0.963 rs12494304 chr3:48178029 C/T cg11946769 chr3:48343235 NME6 -0.59 -5.27 -0.43 5.75e-7 Coronary artery disease; TGCT cis rs1670533 0.932 rs3796620 chr4:1095079 A/G cg20518497 chr4:1046821 NA 0.27 4.46 0.37 1.84e-5 Recombination rate (females); TGCT cis rs514406 0.825 rs3863643 chr1:53224577 C/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.82 -0.62 8.9e-15 Monocyte count; TGCT cis rs4819052 0.851 rs2838855 chr21:46680566 C/G cg06618935 chr21:46677482 NA 0.37 5.56 0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8014252 0.803 rs1959477 chr14:71034216 A/G cg11204974 chr14:71022665 NA -0.55 -4.66 -0.39 7.98e-6 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs12681288 0.676 rs2701927 chr8:995886 G/A cg04851639 chr8:1020857 NA -0.32 -5.37 -0.43 3.81e-7 Schizophrenia; TGCT cis rs600231 0.665 rs1784858 chr11:65222952 T/C cg17120908 chr11:65337727 SSSCA1 -0.51 -4.71 -0.39 6.59e-6 Bone mineral density; TGCT cis rs1218582 0.774 rs4845681 chr1:154868055 G/T cg24250549 chr1:154909240 PMVK 0.56 5.27 0.43 5.95e-7 Prostate cancer; TGCT cis rs4988958 0.565 rs1420100 chr2:103037002 C/A cg03938978 chr2:103052716 IL18RAP 0.27 5.4 0.44 3.31e-7 Asthma (childhood onset); TGCT cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg08280861 chr8:58055591 NA 0.48 5.11 0.42 1.21e-6 Developmental language disorder (linguistic errors); TGCT cis rs1857353 0.803 rs2040082 chr1:75906874 A/G cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7524258 0.900 rs1476047 chr1:7312172 C/T cg04342483 chr1:7259290 CAMTA1 -0.31 -4.51 -0.38 1.47e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9650657 0.655 rs10093774 chr8:10703293 C/T cg27411982 chr8:10470053 RP1L1 0.23 4.67 0.39 7.71e-6 Neuroticism; TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg15242686 chr22:24348715 GSTTP1 0.43 5.95 0.47 2.54e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1971762 0.545 rs10747676 chr12:54049930 T/C cg16917193 chr12:54089295 NA 1.05 10.91 0.7 7.89e-20 Height; TGCT cis rs2404602 0.967 rs2083762 chr15:76907376 T/C cg22467129 chr15:76604101 ETFA -0.45 -4.95 -0.41 2.35e-6 Blood metabolite levels; TGCT cis rs10114408 0.959 rs1933672 chr9:96654908 A/C cg13679303 chr9:96623674 NA -0.35 -4.45 -0.37 1.86e-5 Colorectal cancer (SNP x SNP interaction); TGCT trans rs916888 0.610 rs199530 chr17:44836653 C/T cg01341218 chr17:43662625 NA -0.79 -7.11 -0.54 7.91e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1008375 1.000 rs9291659 chr4:17662360 A/C cg10189774 chr4:17578691 LAP3 0.54 4.97 0.41 2.21e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6951245 0.507 rs11976805 chr7:1138716 C/T cg18402987 chr7:1209562 NA 0.45 4.56 0.38 1.23e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2066819 1.000 rs11575229 chr12:56750737 C/T cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs9486719 1.000 rs9486719 chr6:97060124 G/A cg06623918 chr6:96969491 KIAA0776 -0.97 -8.46 -0.61 6.24e-14 Migraine;Coronary artery disease; TGCT cis rs939574 0.799 rs1109867 chr2:220083453 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.04 -6.24 -0.49 6.22e-9 Platelet distribution width; TGCT cis rs12477438 0.798 rs1580068 chr2:99649969 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2013441 0.786 rs4003797 chr17:20288900 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.52 -0.38 1.4e-5 Obesity-related traits; TGCT cis rs35306767 0.714 rs28512382 chr10:1092195 G/C cg18964960 chr10:1102726 WDR37 0.66 4.57 0.38 1.14e-5 Eosinophil percentage of granulocytes; TGCT cis rs7909074 0.798 rs914699 chr10:45377066 A/C cg05187965 chr10:45406764 TMEM72 -0.28 -5.9 -0.47 3.3e-8 Mean corpuscular volume; TGCT cis rs79349575 0.749 rs2270574 chr17:47022270 C/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs36051895 0.664 rs62543877 chr9:5093465 C/A cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs7220401 0.512 rs2289629 chr17:27959903 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 6.77 0.52 4.6e-10 Coronary artery disease; TGCT cis rs13242816 1.000 rs56309428 chr7:116150137 G/T cg02799643 chr7:116139180 CAV2 -0.42 -5.46 -0.44 2.45e-7 P wave duration; TGCT cis rs7226408 0.739 rs115893729 chr18:34343144 C/T cg06757138 chr18:34340585 FHOD3 0.3 5.09 0.42 1.3e-6 Obesity-related traits; TGCT cis rs902774 0.554 rs4503623 chr12:53353759 T/C cg14581129 chr12:53358946 NA -0.56 -6.08 -0.48 1.34e-8 Prostate cancer; TGCT cis rs926938 0.527 rs360684 chr1:115499001 A/G cg12756093 chr1:115239321 AMPD1 0.35 5.1 0.42 1.25e-6 Autism; TGCT cis rs2178146 0.535 rs4843370 chr16:86450509 G/A cg11165158 chr16:86613094 FOXL1 0.35 4.69 0.39 7.09e-6 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT trans rs7618501 0.602 rs2526743 chr3:50115245 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.5 -0.65 2.02e-16 Intelligence (multi-trait analysis); TGCT cis rs3796352 0.892 rs11718388 chr3:53076415 G/A cg27565382 chr3:53032988 SFMBT1 0.43 4.62 0.38 9.64e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs62103177 0.608 rs551643 chr18:77838970 C/G cg07235805 chr18:78004237 PARD6G -0.51 -4.98 -0.41 2.11e-6 Opioid sensitivity; TGCT cis rs6558530 0.836 rs11136424 chr8:1717036 C/T cg09410841 chr8:1729607 CLN8 0.89 10.54 0.69 6.17e-19 Systolic blood pressure; TGCT cis rs2836950 0.509 rs11088466 chr21:40580017 T/A cg11890956 chr21:40555474 PSMG1 -0.68 -6.58 -0.51 1.21e-9 Menarche (age at onset); TGCT cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs813218 0.523 rs10935917 chr3:99441241 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.13 0.42 1.07e-6 Orofacial clefts; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs1552244 0.882 rs13088350 chr3:10044626 T/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs60843830 1.000 rs79716074 chr2:277003 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.73 7.33 0.55 2.65e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg21724239 chr8:58056113 NA -0.39 -4.96 -0.41 2.29e-6 Developmental language disorder (linguistic errors); TGCT cis rs7923609 0.967 rs7076310 chr10:65135672 C/A cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.15e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs7226408 0.857 rs72887034 chr18:34474187 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg11062466 chr8:58055876 NA 0.37 4.63 0.38 9.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs7580717 0.540 rs62197320 chr2:232060366 T/G cg07929768 chr2:232055508 NA 0.31 4.93 0.41 2.55e-6 Multiple myeloma; TGCT cis rs854765 0.583 rs9908832 chr17:17871068 C/T cg09796270 chr17:17721594 SREBF1 0.23 4.56 0.38 1.22e-5 Total body bone mineral density; TGCT cis rs6461049 0.608 rs3800923 chr7:2184673 A/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.74 -0.52 5.43e-10 Schizophrenia; TGCT trans rs1814175 0.817 rs11493756 chr11:50017885 T/C cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs11690935 1.000 rs312918 chr2:172569587 C/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg13695892 chr22:41940480 POLR3H -0.92 -9.23 -0.64 9.18e-16 Vitiligo; TGCT cis rs12681287 0.577 rs11992955 chr8:87530485 A/G cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs2016266 0.855 rs6580941 chr12:53662199 T/C cg16917193 chr12:54089295 NA 0.69 5.24 0.43 6.71e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs6540559 0.673 rs114467813 chr1:210017785 G/A cg22029157 chr1:209979665 IRF6 0.7 4.96 0.41 2.26e-6 Cleft lip with or without cleft palate; TGCT cis rs736408 0.812 rs2071508 chr3:52826846 A/G cg07507251 chr3:52567010 NT5DC2 -0.43 -5.82 -0.46 4.67e-8 Bipolar disorder; TGCT cis rs2762353 0.574 rs4419666 chr6:25693274 C/T cg15691649 chr6:25882328 NA 0.48 5.64 0.45 1.11e-7 Blood metabolite levels; TGCT cis rs7772486 0.790 rs2814880 chr6:146208937 T/G cg23711669 chr6:146136114 FBXO30 0.89 10.18 0.67 4.61e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs10540 0.730 rs12789735 chr11:518509 G/A cg03934478 chr11:495069 RNH1 0.32 4.82 0.4 4.16e-6 Body mass index; TGCT cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg06634786 chr22:41940651 POLR3H 0.87 8.2 0.59 2.56e-13 Vitiligo; TGCT cis rs3617 0.573 rs2336667 chr3:52916363 C/T cg10802521 chr3:52805072 NEK4 0.57 6.57 0.51 1.27e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs12220898 0.749 rs6537520 chr10:50484107 T/C cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9787249 0.957 rs12086750 chr1:40210468 G/C cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs2439831 1.000 rs2467743 chr15:43750346 T/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.18 0.59 2.83e-13 Lung cancer in ever smokers; TGCT cis rs9807989 0.839 rs1420099 chr2:102980543 C/G cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs9300255 0.507 rs1727302 chr12:123632930 G/A cg00376283 chr12:123451042 ABCB9 0.78 6.66 0.51 8.08e-10 Neutrophil percentage of white cells; TGCT cis rs6912958 0.781 rs9444519 chr6:88290398 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs10479542 0.766 rs6894980 chr5:178974592 C/T cg00080972 chr5:178986291 RUFY1 0.46 5.39 0.44 3.46e-7 Lung cancer; TGCT cis rs6845621 0.901 rs7697728 chr4:18922514 C/T cg12196642 chr4:18937545 NA -0.25 -4.5 -0.38 1.52e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs9905704 0.647 rs12940492 chr17:56954655 C/G cg12560992 chr17:57184187 TRIM37 0.57 4.9 0.4 2.87e-6 Testicular germ cell tumor; TGCT cis rs9638182 0.945 rs13247874 chr7:73010442 C/T cg14087351 chr7:73037990 MLXIPL -0.55 -4.6 -0.38 1.01e-5 Triglycerides; TGCT cis rs11247915 1.000 rs11247915 chr1:26650550 G/T cg23732845 chr1:26663426 AIM1L 0.31 4.46 0.37 1.82e-5 Obesity-related traits; TGCT cis rs7666738 0.830 rs35235971 chr4:98999833 G/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.817 rs12277258 chr11:49940216 T/C cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs13191362 0.935 rs34063386 chr6:163041271 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.5 0.61 5.17e-14 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6061231 0.571 rs482010 chr20:60927551 A/G cg24112000 chr20:60950667 NA 0.34 4.76 0.39 5.24e-6 Colorectal cancer; TGCT cis rs1334894 0.901 rs56353810 chr6:35521086 G/T cg24281267 chr6:35479648 TULP1 -0.43 -4.47 -0.37 1.78e-5 Coronary artery disease; TGCT cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg03264133 chr6:25882463 NA -0.62 -5.72 -0.46 7.56e-8 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.605 rs12709094 chr16:89853017 A/G cg04287289 chr16:89883240 FANCA 0.93 11.83 0.73 4.42e-22 Vitiligo; TGCT cis rs11626933 0.885 rs28517514 chr14:90788709 G/A cg14092571 chr14:90743983 NA -0.27 -5.49 -0.44 2.14e-7 Gut microbiota (bacterial taxa); TGCT cis rs2637266 0.905 rs10824428 chr10:78346041 G/A cg18941641 chr10:78392320 NA 0.42 5.45 0.44 2.62e-7 Pulmonary function; TGCT cis rs6088580 0.634 rs4911151 chr20:32932273 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.9 -0.4 2.97e-6 Glomerular filtration rate (creatinine); TGCT cis rs877282 0.945 rs11253391 chr10:788752 G/A cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs263156 1.000 rs263158 chr6:142909049 G/T cg18419694 chr6:143832440 FUCA2 0.4 4.65 0.39 8.22e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs6500602 0.527 rs13338333 chr16:4443250 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 5.05 0.41 1.53e-6 Schizophrenia; TGCT cis rs67311347 0.544 rs9821440 chr3:40342347 T/C cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs12477438 0.520 rs4851187 chr2:99745860 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -1.05 -12.95 -0.76 8.61e-25 Chronic sinus infection; TGCT cis rs1355223 0.552 rs2421743 chr11:34882840 C/T cg11058730 chr11:34937778 PDHX;APIP 0.8 8.94 0.63 4.49e-15 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs7010267 0.740 rs1872426 chr8:119949756 A/C cg17171407 chr8:119960777 TNFRSF11B -0.25 -4.44 -0.37 2e-5 Total body bone mineral density (age 45-60); TGCT cis rs2795502 1.000 rs2795497 chr10:43339475 C/A cg20628663 chr10:43360327 NA -0.44 -6.37 -0.5 3.4e-9 Blood protein levels; TGCT cis rs473651 0.935 rs1103770 chr2:239339281 G/C cg08773314 chr2:239334832 ASB1 0.45 6.39 0.5 3.05e-9 Multiple system atrophy; TGCT cis rs7937682 0.881 rs4936678 chr11:111625085 C/T cg03242880 chr11:111382915 BTG4;MIR34C;MIR34B -0.25 -4.49 -0.37 1.58e-5 Primary sclerosing cholangitis; TGCT cis rs700651 0.624 rs12105927 chr2:198937258 G/A cg00792783 chr2:198669748 PLCL1 0.58 5.16 0.42 9.47e-7 Intracranial aneurysm; TGCT cis rs7666738 0.791 rs6853608 chr4:99047916 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4383453 0.539 rs2332509 chr3:123100177 T/C cg04890266 chr3:123102914 ADCY5 -0.5 -8.19 -0.59 2.68e-13 Gestational age at birth (maternal effect); TGCT cis rs12220898 0.749 rs4497321 chr10:50475018 C/T cg06072769 chr10:50146962 WDFY4 0.36 4.67 0.39 7.64e-6 Inflammatory biomarkers; TGCT trans rs1005277 0.540 rs2224248 chr10:38451886 A/G cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.5e-21 Extrinsic epigenetic age acceleration; TGCT trans rs11088226 0.681 rs11700670 chr21:33938615 T/C cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT cis rs8037137 0.915 rs112770790 chr15:91507495 G/A cg22570213 chr15:91497863 RCCD1 0.52 4.84 0.4 3.85e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs9467773 0.869 rs9295689 chr6:26455811 T/C cg09904177 chr6:26538194 HMGN4 0.56 5.43 0.44 2.8e-7 Intelligence (multi-trait analysis); TGCT cis rs290268 0.838 rs290993 chr9:93559572 G/A cg02608019 chr9:93564028 SYK 0.46 4.69 0.39 7.07e-6 Platelet count; TGCT cis rs7582180 0.676 rs4264577 chr2:100930662 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs7578597 chr2:43732823 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.5 0.37 1.57e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7226408 0.857 rs55992510 chr18:34519130 G/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs4805272 0.512 rs66830923 chr19:29321277 C/T cg14983838 chr19:29218262 NA 0.69 4.7 0.39 6.67e-6 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs986417 0.901 rs1955698 chr14:61029936 C/T cg27398547 chr14:60952738 C14orf39 1.33 10.37 0.68 1.56e-18 Gut microbiota (bacterial taxa); TGCT cis rs2235642 0.750 rs763152 chr16:1658056 T/C cg08296037 chr16:1584118 IFT140;TMEM204 -0.29 -5.01 -0.41 1.8e-6 Coronary artery disease; TGCT cis rs10540 1.000 rs79440439 chr11:478147 A/C cg03934478 chr11:495069 RNH1 0.33 5.08 0.42 1.33e-6 Body mass index; TGCT trans rs3780486 0.846 rs3780487 chr9:33139237 T/C cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT cis rs12477438 0.520 rs13018891 chr2:99755099 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs1878931 0.501 rs37800 chr16:3423648 T/G cg22508957 chr16:3507546 NAT15 0.4 5.24 0.43 6.71e-7 Body mass index (adult); TGCT cis rs6964587 1.000 rs2188154 chr7:91595138 T/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs10479542 0.892 rs7723230 chr5:178980474 T/C cg19723775 chr5:179050963 HNRNPH1 0.53 5.29 0.43 5.29e-7 Lung cancer; TGCT cis rs10791323 0.604 rs2723607 chr11:133711018 C/G cg03690763 chr11:133734501 NA -0.31 -4.79 -0.39 4.72e-6 Childhood ear infection; TGCT cis rs4851266 1.000 rs4583487 chr2:100837126 G/T cg22139774 chr2:100720529 AFF3 -0.34 -5.09 -0.42 1.28e-6 Educational attainment; TGCT cis rs3617 0.625 rs2239548 chr3:52854186 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.6 -0.38 1.02e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs1005277 0.579 rs2983343 chr10:38383332 A/G cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.13e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2469997 0.925 rs2470011 chr8:120359937 G/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs79121401 0.744 rs6592813 chr11:78696828 A/G cg25632648 chr11:77899776 KCTD21;USP35 1.14 4.69 0.39 7.22e-6 Interleukin-12p70 levels; TGCT cis rs713587 0.967 rs10865320 chr2:25159780 A/G cg15423357 chr2:25149977 NA 0.58 5.85 0.46 4.18e-8 Body mass index in non-asthmatics; TGCT cis rs11190604 1.000 rs12219158 chr10:102302923 T/C cg23241863 chr10:102295624 HIF1AN 0.7 5.14 0.42 1.02e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg11905131 chr22:24372483 LOC391322 -1.03 -13.34 -0.77 9.82e-26 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9914544 1.000 rs1634409 chr17:18836177 C/T cg26306683 chr17:18585705 ZNF286B 0.59 5.26 0.43 5.99e-7 Educational attainment (years of education); TGCT cis rs473651 0.935 rs483166 chr2:239346641 C/T cg08773314 chr2:239334832 ASB1 -0.45 -7.5 -0.56 1.07e-11 Multiple system atrophy; TGCT cis rs1577917 1.000 rs6914463 chr6:86653415 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs67311347 0.911 rs9863737 chr3:40439836 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs116095464 0.558 rs61492827 chr5:225774 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs1801251 0.963 rs13424351 chr2:233573629 A/G cg25237894 chr2:233734115 C2orf82 0.3 5.3 0.43 5.08e-7 Coronary artery disease; TGCT cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.67 -6.89 -0.53 2.53e-10 Prostate cancer; TGCT cis rs12049351 0.774 rs1053513 chr1:229652587 T/C cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7666738 0.830 rs13134819 chr4:98919885 G/C cg17366294 chr4:99064904 C4orf37 0.73 7.51 0.56 1e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs13102973 0.646 rs4428339 chr4:135886187 C/T cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs13082711 0.648 rs13085782 chr3:27404390 C/G cg02860705 chr3:27208620 NA 0.51 7.37 0.55 2.09e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs12780845 0.540 rs10795451 chr10:17179195 T/C cg01003015 chr10:17271136 VIM -0.59 -5.5 -0.44 2.11e-7 Homocysteine levels; TGCT cis rs6964587 0.935 rs9770444 chr7:91783162 T/G cg17063962 chr7:91808500 NA 0.93 10.08 0.67 8.03e-18 Breast cancer; TGCT cis rs7945705 0.967 rs34842234 chr11:8891894 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.86 0.4 3.42e-6 Hemoglobin concentration; TGCT cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.932 rs56306759 chr21:40608106 G/A cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.67e-16 Cognitive function; TGCT cis rs28595532 0.920 rs10025640 chr4:119787451 G/A cg14228332 chr4:119757509 SEC24D 1.19 6.66 0.51 8.07e-10 Cannabis dependence symptom count; TGCT cis rs12188164 0.965 rs72717430 chr5:444502 T/C cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs1997103 0.954 rs9649780 chr7:55411741 A/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9916302 0.904 rs11869109 chr17:37518205 G/T cg15445000 chr17:37608096 MED1 -0.33 -4.74 -0.39 5.87e-6 Glomerular filtration rate (creatinine); TGCT cis rs295140 0.605 rs3769471 chr2:201195403 G/A cg04283868 chr2:201171347 SPATS2L 0.48 4.59 0.38 1.07e-5 QT interval; TGCT cis rs2859741 0.935 rs2782410 chr1:37509489 G/C cg09363841 chr1:37513479 NA -0.19 -4.48 -0.37 1.65e-5 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs7100689 0.784 rs17678947 chr10:82136333 T/C cg01528321 chr10:82214614 TSPAN14 0.87 8.35 0.6 1.14e-13 Post bronchodilator FEV1; TGCT cis rs6089584 0.507 rs28545731 chr20:60634102 C/T cg13665807 chr20:60559372 TAF4 -0.48 -5.08 -0.42 1.35e-6 Body mass index; TGCT cis rs6964587 1.000 rs7785971 chr7:91736794 T/A cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.21e-5 Breast cancer; TGCT trans rs75565482 0.546 rs12090359 chr1:168458546 G/A cg15721615 chr1:100771427 NA 0.49 6.84 0.52 3.23e-10 Emphysema imaging phenotypes; TGCT cis rs12681287 0.547 rs9942823 chr8:87509177 A/G cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -4.96 -0.41 2.27e-6 Coronary artery disease; TGCT cis rs8017423 0.935 rs2104704 chr14:90696609 A/G cg04374321 chr14:90722782 PSMC1 -0.76 -7.85 -0.58 1.64e-12 Mortality in heart failure; TGCT cis rs9357506 1.000 rs9369611 chr6:46313249 G/A cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9393692 0.676 rs1543681 chr6:26187783 G/T cg05868516 chr6:26286170 HIST1H4H 0.53 5.13 0.42 1.06e-6 Educational attainment; TGCT cis rs3099143 0.908 rs6495222 chr15:77180015 A/C cg21673338 chr15:77095150 SCAPER 0.52 5.05 0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs748404 0.660 rs2467741 chr15:43742626 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.77 0.39 5.17e-6 Lung cancer; TGCT cis rs28595532 0.920 rs115681185 chr4:119757700 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg16145915 chr7:1198662 ZFAND2A -0.45 -5.43 -0.44 2.85e-7 Longevity;Endometriosis; TGCT trans rs2688608 0.617 rs6480709 chr10:75479125 T/C cg13918328 chr10:52500089 ASAH2B 0.68 6.73 0.52 5.68e-10 Inflammatory bowel disease; TGCT cis rs7949030 0.626 rs7943191 chr11:62328551 A/G cg22862634 chr11:62369728 EML3;MTA2 0.71 9.07 0.63 2.23e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4268898 0.560 rs78711174 chr2:24496531 G/A cg06627628 chr2:24431161 ITSN2 -0.2 -4.46 -0.37 1.82e-5 Asthma; TGCT cis rs3749237 0.537 rs4459909 chr3:49469217 T/C cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs6089829 0.888 rs4809465 chr20:61671156 G/C cg08045932 chr20:61659980 NA 0.5 8.69 0.62 1.75e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg10802521 chr3:52805072 NEK4 -0.7 -8.64 -0.61 2.37e-14 Bipolar disorder; TGCT cis rs9467711 0.790 rs45527431 chr6:26599509 A/G cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs611744 0.967 rs608115 chr8:109231948 T/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7833790 0.660 rs1451995 chr8:82746123 G/C cg27398817 chr8:82754497 SNX16 0.67 5.34 0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs6540559 0.546 rs735694 chr1:210034029 T/C cg12034118 chr1:209979487 IRF6 0.65 4.56 0.38 1.2e-5 Cleft lip with or without cleft palate; TGCT cis rs3902035 0.964 rs62423960 chr6:119008133 T/C cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs597539 0.689 rs596874 chr11:68630874 C/T cg21862992 chr11:68658383 NA -0.45 -6.19 -0.49 7.89e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg04546413 chr19:29218101 NA 0.86 7.0 0.53 1.45e-10 Methadone dose in opioid dependence; TGCT cis rs6782228 1.000 rs35871360 chr3:128336129 G/A cg15113803 chr3:129247119 RHO 0.17 4.47 0.37 1.72e-5 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; TGCT cis rs1799949 0.602 rs8176235 chr17:41219560 C/T cg05368731 chr17:41323189 NBR1 1.01 9.03 0.63 2.83e-15 Menopause (age at onset); TGCT cis rs597539 0.652 rs544370 chr11:68653232 C/T cg06028808 chr11:68637592 NA 0.51 6.55 0.51 1.38e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.515 rs10015315 chr4:98700137 A/G cg17366294 chr4:99064904 C4orf37 0.59 5.57 0.45 1.48e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.632 rs1581927 chr9:5177462 C/T cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.2e-20 Pediatric autoimmune diseases; TGCT cis rs9916302 0.851 rs11078906 chr17:37662767 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs4072705 1.000 rs10760372 chr9:127468816 T/C cg13476313 chr9:127244764 NR5A1 0.29 4.65 0.39 8.5e-6 Menarche (age at onset); TGCT cis rs589448 0.902 rs642786 chr12:69758462 T/C cg14784868 chr12:69753453 YEATS4 0.89 10.48 0.69 8.4e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs4862750 0.914 rs1991256 chr4:187875330 A/G cg11301795 chr4:187892539 NA -0.36 -5.55 -0.45 1.66e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg24531977 chr5:56204891 C5orf35 -0.72 -7.31 -0.55 2.9e-11 Initial pursuit acceleration; TGCT cis rs7246657 0.639 rs12459015 chr19:38083189 T/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs28374715 0.532 rs28584379 chr15:41670408 C/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -16.21 -0.82 2.08e-32 Ulcerative colitis; TGCT cis rs763014 0.931 rs710925 chr16:633354 G/A cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs3812049 0.667 rs6888037 chr5:127406259 G/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.6 5.57 0.45 1.47e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs3796352 1.000 rs34121720 chr3:53072167 C/T cg15956490 chr3:53032818 SFMBT1 0.59 6.75 0.52 5.19e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2996428 0.667 rs111640545 chr1:3752792 G/A cg17848003 chr1:3704513 LRRC47 0.19 5.14 0.42 1.04e-6 Red cell distribution width; TGCT trans rs7618501 0.669 rs3774758 chr3:49938227 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.89 9.83 0.66 3.36e-17 Intelligence (multi-trait analysis); TGCT cis rs9291683 0.588 rs4697705 chr4:10108127 G/A cg00071950 chr4:10020882 SLC2A9 -0.42 -4.6 -0.38 1.01e-5 Bone mineral density; TGCT cis rs1048238 0.506 rs1262788 chr1:16215608 G/C cg21385522 chr1:16154831 NA -0.61 -6.88 -0.53 2.64e-10 Systolic blood pressure; TGCT cis rs7246657 0.882 rs59224125 chr19:37963205 T/C cg18154014 chr19:37997991 ZNF793 0.73 5.33 0.43 4.4e-7 Coronary artery calcification; TGCT cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg06697600 chr4:7070879 GRPEL1 0.43 4.55 0.38 1.24e-5 Monocyte percentage of white cells; TGCT cis rs2153535 0.580 rs969421 chr6:8451949 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs7772486 0.590 rs1890170 chr6:146071839 G/C cg05347473 chr6:146136440 FBXO30 -0.68 -6.22 -0.49 7.01e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs13315871 1.000 rs9869576 chr3:58401262 G/A cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs3733585 0.725 rs6449201 chr4:9973894 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.72 -0.52 5.74e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11690935 0.798 rs13018768 chr2:172598592 A/G cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.41 -0.74 1.75e-23 Schizophrenia; TGCT cis rs6964587 1.000 rs2285333 chr7:91667692 T/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs7584330 0.910 rs66509917 chr2:238395394 T/G cg08992911 chr2:238395768 MLPH 0.63 5.2 0.42 8.03e-7 Prostate cancer; TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg03404566 chr17:6899310 ALOX12 0.47 5.26 0.43 6.17e-7 Tonsillectomy; TGCT cis rs875971 0.660 rs3857686 chr7:66036191 C/T cg18876405 chr7:65276391 NA -0.37 -5.58 -0.45 1.47e-7 Aortic root size; TGCT cis rs12681287 0.752 rs4288357 chr8:87251833 C/T cg27223183 chr8:87520930 FAM82B -0.8 -5.67 -0.45 9.58e-8 Caudate activity during reward; TGCT cis rs6547741 1.000 rs6547734 chr2:27830990 G/T cg27432699 chr2:27873401 GPN1 0.18 4.65 0.38 8.53e-6 Oral cavity cancer; TGCT cis rs782590 0.967 rs11125581 chr2:55796527 C/G cg18811423 chr2:55921094 PNPT1 0.65 6.92 0.53 2.12e-10 Metabolic syndrome; TGCT cis rs12410462 0.502 rs114121935 chr1:227959336 A/G cg23173402 chr1:227635558 NA 0.7 4.81 0.4 4.31e-6 Major depressive disorder; TGCT cis rs11690935 0.589 rs2271758 chr2:172701157 T/G cg13550731 chr2:172543902 DYNC1I2 0.72 6.32 0.49 4.2e-9 Schizophrenia; TGCT cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg17971929 chr21:40555470 PSMG1 -0.68 -5.96 -0.47 2.42e-8 Cognitive function; TGCT cis rs6598955 0.671 rs12354062 chr1:26608761 C/T cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs713587 0.520 rs493090 chr2:25303772 G/A cg01884057 chr2:25150051 NA -0.25 -4.64 -0.38 8.56e-6 Body mass index in non-asthmatics; TGCT cis rs7681440 0.904 rs6816736 chr4:90765746 G/A cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs7666738 0.716 rs28792413 chr4:99083707 G/A cg17366294 chr4:99064904 C4orf37 0.68 6.69 0.51 6.92e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs13108705 chr4:99044438 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs988712 0.705 rs4074134 chr11:27647285 C/T cg10635145 chr11:27742435 BDNF -0.38 -5.23 -0.43 7e-7 Obesity; TGCT cis rs67311347 1.000 rs1454497 chr3:40496326 C/T cg13683864 chr3:40499215 RPL14 1.16 12.09 0.74 1.04e-22 Renal cell carcinoma; TGCT cis rs78487399 0.808 rs6731980 chr2:43703183 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4730250 0.708 rs4730242 chr7:107057373 G/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Osteoarthritis; TGCT cis rs7917772 0.502 rs4919670 chr10:104515799 C/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.57 -4.73 -0.39 6.01e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9467773 0.804 rs2073526 chr6:26374658 C/T cg26531700 chr6:26746687 NA -0.54 -5.2 -0.42 8.06e-7 Intelligence (multi-trait analysis); TGCT cis rs9894429 1.000 rs7213129 chr17:79581573 C/T cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs1577917 1.000 rs12199784 chr6:86726808 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs904251 0.525 rs12200378 chr6:37425304 A/G cg01843034 chr6:37503916 NA -0.48 -6.04 -0.48 1.65e-8 Cognitive performance; TGCT cis rs9653442 1.000 rs6712515 chr2:100806514 T/C cg22139774 chr2:100720529 AFF3 -0.48 -8.71 -0.62 1.57e-14 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs34424131 chr7:116119002 G/A cg02799643 chr7:116139180 CAV2 -0.49 -5.61 -0.45 1.27e-7 P wave duration; TGCT cis rs9905704 0.647 rs11079367 chr17:57009024 A/G cg05425664 chr17:57184151 TRIM37 -0.57 -4.44 -0.37 1.97e-5 Testicular germ cell tumor; TGCT cis rs9486719 0.857 rs11759769 chr6:97065212 G/A cg06623918 chr6:96969491 KIAA0776 -1.06 -9.8 -0.66 3.95e-17 Migraine;Coronary artery disease; TGCT cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT trans rs7726839 0.540 rs72703092 chr5:599269 G/A cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs9303401 0.659 rs61291849 chr17:56909867 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs1801251 0.778 rs812383 chr2:233737132 C/A cg25237894 chr2:233734115 C2orf82 -0.31 -5.98 -0.47 2.2e-8 Coronary artery disease; TGCT cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg09177884 chr7:1199841 ZFAND2A -0.53 -5.01 -0.41 1.81e-6 Longevity;Endometriosis; TGCT cis rs3617 0.572 rs2245538 chr3:52852060 T/C cg11645453 chr3:52864694 ITIH4 0.28 5.45 0.44 2.63e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1129187 0.935 rs9462859 chr6:42946943 G/A cg02353165 chr6:42928485 GNMT 0.98 10.18 0.67 4.7e-18 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6540559 0.673 rs11805830 chr1:209984969 C/T cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs2692947 0.537 rs4907274 chr2:96363682 G/A cg23100626 chr2:96804247 ASTL 0.46 5.53 0.44 1.79e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs875971 0.825 rs1129531 chr7:65619104 C/T cg11764359 chr7:65958608 NA -0.58 -5.27 -0.43 5.83e-7 Aortic root size; TGCT cis rs916888 0.610 rs199536 chr17:44820425 T/C cg15921436 chr17:44337874 NA -0.41 -6.27 -0.49 5.47e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2013441 1.000 rs2526475 chr17:20136216 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs2060793 0.741 rs10741653 chr11:14704840 C/A cg00085434 chr11:14927489 NA 0.34 4.78 0.39 4.8e-6 Vitamin D levels; TGCT cis rs40363 0.645 rs250633 chr16:3523002 C/T cg00484396 chr16:3507460 NAT15 0.42 6.36 0.5 3.59e-9 Tuberculosis; TGCT cis rs17376456 0.877 rs34184666 chr5:93444584 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg08859206 chr1:53392774 SCP2 -0.46 -7.42 -0.55 1.64e-11 Monocyte count; TGCT cis rs7267979 1.000 rs2387884 chr20:25379069 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg21724239 chr8:58056113 NA 0.44 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs6671200 0.541 rs7555339 chr1:95691579 G/A cg20701556 chr1:95698924 RWDD3 -0.53 -5.37 -0.43 3.7e-7 Stearic acid (18:0) levels; TGCT cis rs7681440 0.835 rs6532198 chr4:90798870 C/T cg26578617 chr4:90757533 SNCA -0.45 -4.63 -0.38 9.12e-6 Dementia with Lewy bodies; TGCT cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg11279151 chr3:101281821 RG9MTD1 0.45 9.64 0.65 9.35e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs4919044 0.735 rs835245 chr10:94759873 A/T cg05127821 chr10:94822908 CYP26C1 -0.57 -4.44 -0.37 1.95e-5 Coronary artery disease; TGCT cis rs7937682 0.924 rs7938360 chr11:111539875 A/G cg09085632 chr11:111637200 PPP2R1B -1.14 -12.06 -0.73 1.22e-22 Primary sclerosing cholangitis; TGCT cis rs7698623 0.850 rs4693896 chr4:88797897 T/C cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs72781680 0.821 rs2176265 chr2:24158638 C/G cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs7772486 0.875 rs2814874 chr6:146305895 C/T cg05347473 chr6:146136440 FBXO30 0.55 5.11 0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089584 1.000 rs3787425 chr20:60559256 C/T cg06108461 chr20:60628389 TAF4 -0.57 -8.01 -0.58 7.25e-13 Body mass index; TGCT cis rs7659604 0.539 rs72680779 chr4:122797263 C/T cg20573242 chr4:122745356 CCNA2 0.6 5.22 0.42 7.17e-7 Type 2 diabetes; TGCT cis rs9905704 0.624 rs8080071 chr17:57093825 C/T cg12560992 chr17:57184187 TRIM37 -0.62 -5.52 -0.44 1.9e-7 Testicular germ cell tumor; TGCT cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg26116260 chr4:7069785 GRPEL1 1.12 10.96 0.7 5.83e-20 Monocyte percentage of white cells; TGCT cis rs425277 0.958 rs262660 chr1:2086757 A/G cg03732007 chr1:2071316 PRKCZ 0.26 5.52 0.44 1.89e-7 Height; TGCT cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg03264133 chr6:25882463 NA -0.5 -5.2 -0.42 8.12e-7 Height; TGCT cis rs7666738 0.535 rs6850010 chr4:98971601 A/T cg05340658 chr4:99064831 C4orf37 0.5 5.55 0.45 1.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1971762 0.583 rs12810378 chr12:54091838 G/T cg16917193 chr12:54089295 NA 1.32 17.62 0.85 1.5e-35 Height; TGCT cis rs524023 0.874 rs518053 chr11:64456099 C/T cg19395706 chr11:64412079 NRXN2 -0.36 -4.44 -0.37 1.96e-5 Urate levels in obese individuals; TGCT cis rs9894429 0.816 rs7406040 chr17:79597583 A/C cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs9399135 0.967 rs9376085 chr6:135371224 T/C cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs13242816 1.000 rs67982517 chr7:116075363 A/G cg16553024 chr7:116138462 CAV2 -0.47 -5.25 -0.43 6.52e-7 P wave duration; TGCT cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs854765 0.583 rs11650649 chr17:17790319 C/A cg09796270 chr17:17721594 SREBF1 -0.27 -5.5 -0.44 2.04e-7 Total body bone mineral density; TGCT cis rs2458413 0.522 rs2514657 chr8:105331215 T/C cg23108931 chr8:105342351 NA -0.34 -5.74 -0.46 6.76e-8 Paget's disease; TGCT cis rs9322193 0.923 rs10782310 chr6:149943594 A/G cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs17401966 0.540 rs4846219 chr1:10463888 C/A cg19773385 chr1:10388646 KIF1B -0.23 -5.46 -0.44 2.52e-7 Hepatocellular carcinoma; TGCT cis rs1903068 0.785 rs28584303 chr4:55997622 C/T cg09978860 chr4:56023921 NA 0.56 6.24 0.49 6.22e-9 Endometriosis; TGCT cis rs11785400 0.612 rs10110864 chr8:143750072 A/G cg24634471 chr8:143751801 JRK 0.57 5.96 0.47 2.38e-8 Schizophrenia; TGCT cis rs6840360 0.638 rs6816002 chr4:152589439 C/T cg17479576 chr4:152424074 FAM160A1 -0.61 -6.29 -0.49 4.94e-9 Intelligence (multi-trait analysis); TGCT cis rs7044106 0.762 rs10984974 chr9:123421556 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.6 6.29 0.49 4.98e-9 Hip circumference adjusted for BMI; TGCT cis rs7542091 0.666 rs7537070 chr1:210043565 A/G cg00989853 chr1:209979345 IRF6 0.43 4.58 0.38 1.12e-5 Monobrow; TGCT trans rs7618501 0.966 rs9882639 chr3:49799475 A/C cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs12421382 0.511 rs2212430 chr11:109289538 C/T cg27471124 chr11:109292789 C11orf87 0.48 5.73 0.46 7.32e-8 Schizophrenia; TGCT cis rs10901296 0.660 rs11789055 chr9:133766295 T/C cg01000188 chr9:133769184 QRFP 0.33 4.46 0.37 1.84e-5 Bilirubin levels; TGCT cis rs7726839 0.540 rs11739847 chr5:609661 G/A cg09021430 chr5:549028 NA -0.46 -6.09 -0.48 1.3e-8 Obesity-related traits; TGCT cis rs9291683 1.000 rs9291683 chr4:10324160 C/T cg00071950 chr4:10020882 SLC2A9 0.46 4.85 0.4 3.6e-6 Bone mineral density; TGCT cis rs155076 0.666 rs2015241 chr13:21888254 A/G cg25811766 chr13:21894605 NA 0.32 4.53 0.38 1.36e-5 White matter hyperintensity burden; TGCT cis rs735396 0.770 rs2259820 chr12:121435342 C/T cg15155738 chr12:121454335 C12orf43 0.52 4.56 0.38 1.19e-5 N-glycan levels; TGCT cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 6.08 0.48 1.36e-8 Menarche (age at onset); TGCT cis rs2688608 0.620 rs7080350 chr10:75577843 A/G cg19442545 chr10:75533431 FUT11 0.36 5.87 0.47 3.69e-8 Inflammatory bowel disease; TGCT cis rs67072384 0.892 rs67034709 chr11:72451004 T/C cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs1395 0.778 rs1439767 chr2:27389634 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.66 8.95 0.63 4.24e-15 Blood metabolite levels; TGCT cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg05738196 chr6:26577821 NA 0.49 4.71 0.39 6.47e-6 Schizophrenia; TGCT cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.807 rs28715237 chr21:46673768 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4803468 1.000 rs2241708 chr19:41912270 C/T cg09537434 chr19:41945824 ATP5SL -0.92 -10.83 -0.7 1.18e-19 Height; TGCT cis rs514406 0.683 rs6588440 chr1:53209587 C/T cg16325326 chr1:53192061 ZYG11B -0.9 -13.17 -0.76 2.58e-25 Monocyte count; TGCT cis rs7044106 0.791 rs10818473 chr9:123484155 A/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.96 0.41 2.28e-6 Hip circumference adjusted for BMI; TGCT cis rs9790314 0.934 rs455386 chr3:161102495 A/T cg03342759 chr3:160939853 NMD3 -0.44 -4.59 -0.38 1.06e-5 Morning vs. evening chronotype; TGCT cis rs78487399 0.908 rs6725688 chr2:43846553 G/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.58 0.38 1.12e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7611238 0.560 rs10439946 chr3:195080101 T/C cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs72781680 0.898 rs718139 chr2:23975911 G/A cg08917208 chr2:24149416 ATAD2B 0.95 6.09 0.48 1.28e-8 Lymphocyte counts; TGCT cis rs12477438 0.798 rs13409996 chr2:99575497 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs210152 0.588 rs210131 chr6:33535466 T/C cg16739976 chr6:34101401 GRM4 -0.61 -4.95 -0.41 2.4e-6 Schizophrenia; TGCT cis rs9653442 0.545 rs11900482 chr2:100758709 G/C cg22139774 chr2:100720529 AFF3 -0.36 -5.63 -0.45 1.16e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2458413 0.500 rs2514665 chr8:105351531 C/T cg04554929 chr8:105342491 NA 0.5 6.07 0.48 1.42e-8 Paget's disease; TGCT cis rs7617773 0.780 rs79089926 chr3:48348564 A/C cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs10892173 0.566 rs10892174 chr11:117672565 A/C cg21640587 chr11:117668038 DSCAML1 0.71 8.27 0.6 1.73e-13 Myopia; TGCT cis rs7085104 0.700 rs10786712 chr10:104596396 A/G cg05855489 chr10:104503620 C10orf26 -0.54 -4.94 -0.41 2.47e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs12220238 0.915 rs61045754 chr10:76153125 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.88 5.86 0.47 3.87e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs35883536 0.566 rs4908086 chr1:101088124 C/T cg06223162 chr1:101003688 GPR88 0.33 5.33 0.43 4.55e-7 Monocyte count; TGCT cis rs7216064 1.000 rs11079706 chr17:65835470 G/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7086627 0.515 rs12245180 chr10:82211897 C/G cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs2486012 0.649 rs1354261 chr1:44256682 A/C cg12908607 chr1:44402522 ARTN -0.69 -5.74 -0.46 7.02e-8 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.554 rs11789744 chr9:5134213 G/A cg02405213 chr9:5042618 JAK2 -0.71 -9.55 -0.65 1.57e-16 Pediatric autoimmune diseases; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg18538332 chr22:24372958 LOC391322 -1.01 -12.84 -0.76 1.6e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg06634786 chr22:41940651 POLR3H -0.86 -8.01 -0.58 7.16e-13 Vitiligo; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg16325326 chr1:53192061 ZYG11B 0.64 7.11 0.54 8.1e-11 Monocyte count; TGCT cis rs7647973 0.588 rs4855848 chr3:49653457 C/T cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs6582630 0.555 rs2004152 chr12:38478951 C/T cg13010199 chr12:38710504 ALG10B 0.64 5.09 0.42 1.27e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs654950 0.901 rs594656 chr1:41999873 C/T cg06885757 chr1:42089581 HIVEP3 -0.26 -4.46 -0.37 1.83e-5 Airway imaging phenotypes; TGCT cis rs12477438 0.798 rs1580068 chr2:99649969 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs2657888 0.628 rs2638335 chr12:56880672 C/T cg23002907 chr12:56915593 RBMS2 -0.41 -5.41 -0.44 3.15e-7 Adiponectin levels; TGCT cis rs3820068 0.608 rs12734937 chr1:16047726 T/C cg17385448 chr1:15911702 AGMAT 0.35 4.66 0.39 8.1e-6 Systolic blood pressure; TGCT cis rs6121246 0.529 rs6060145 chr20:30178631 T/C cg21427119 chr20:30132790 HM13 -0.44 -6.39 -0.5 3.11e-9 Mean corpuscular hemoglobin; TGCT cis rs7681440 0.967 rs920624 chr4:90748195 T/A cg14346243 chr4:90757452 SNCA -0.57 -5.55 -0.45 1.64e-7 Dementia with Lewy bodies; TGCT cis rs35306767 0.903 rs12249634 chr10:872744 G/A cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs1552244 0.882 rs7633769 chr3:10020622 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs6831352 0.879 rs7434491 chr4:100069847 G/C cg12011299 chr4:100065546 ADH4 -0.46 -5.22 -0.42 7.38e-7 Alcohol dependence; TGCT cis rs11874712 1.000 rs9783887 chr18:43651272 C/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.52 5.0 0.41 1.94e-6 Migraine - clinic-based; TGCT cis rs12908161 0.959 rs34028043 chr15:85231585 G/A cg17173187 chr15:85201210 NMB 0.59 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs9467711 0.606 rs9358930 chr6:26357011 C/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2228479 0.850 rs62056103 chr16:89942781 G/A cg06558623 chr16:89946397 TCF25 0.59 6.73 0.52 5.69e-10 Skin colour saturation; TGCT cis rs2456568 0.900 rs2511373 chr11:93671414 T/C cg26875233 chr11:93583750 C11orf90 -0.45 -5.61 -0.45 1.28e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs11031096 0.655 rs10835736 chr11:4212013 G/A cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1552244 0.882 rs13088350 chr3:10044626 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs1008375 0.966 rs6833808 chr4:17652526 T/A cg18681998 chr4:17616180 MED28 1.06 12.42 0.74 1.62e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs526231 0.543 rs183752 chr5:102507812 T/C cg23492399 chr5:102201601 PAM -0.51 -4.49 -0.37 1.6e-5 Primary biliary cholangitis; TGCT cis rs7917772 0.503 rs1536308 chr10:104288777 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6500602 0.701 rs8053770 chr16:4539030 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.39 6.9 0.53 2.38e-10 Schizophrenia; TGCT cis rs2486288 0.656 rs11632777 chr15:45551045 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs9611519 1.000 rs5751069 chr22:41627775 C/G cg03806693 chr22:41940476 POLR3H -0.68 -6.51 -0.5 1.65e-9 Neuroticism; TGCT cis rs3796352 0.667 rs11720228 chr3:52877270 G/A cg07884673 chr3:53033167 SFMBT1 0.62 5.35 0.43 4.16e-7 Immune reponse to smallpox (secreted IL-2); TGCT trans rs2624839 0.704 rs13064381 chr3:50233317 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.82 7.15 0.54 6.61e-11 Intelligence (multi-trait analysis); TGCT cis rs2299587 0.554 rs2073565 chr8:17743649 T/C cg01800426 chr8:17659068 MTUS1 -0.55 -4.96 -0.41 2.25e-6 Economic and political preferences; TGCT cis rs6840360 0.642 rs56301462 chr4:152452128 T/G cg17479576 chr4:152424074 FAM160A1 -0.65 -7.11 -0.54 8.02e-11 Intelligence (multi-trait analysis); TGCT cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.36 -0.55 2.23e-11 Colorectal cancer; TGCT cis rs2046867 0.862 rs9827405 chr3:72827115 C/T cg25664220 chr3:72788482 NA -0.54 -6.72 -0.52 5.99e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs3733585 0.781 rs4292328 chr4:9970962 C/T cg11266682 chr4:10021025 SLC2A9 -0.62 -8.62 -0.61 2.56e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1050631 1.000 rs3110564 chr18:33701589 C/T cg25426722 chr18:33708991 SLC39A6;ELP2 -0.49 -4.78 -0.39 4.85e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs245880 0.740 rs245897 chr7:29193940 C/T cg17163760 chr7:29186267 CPVL 0.41 5.18 0.42 8.89e-7 Warfarin maintenance dose; TGCT cis rs11696501 0.688 rs6130897 chr20:44330004 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs2688608 0.967 rs2675663 chr10:75660270 T/G cg23231163 chr10:75533350 FUT11 -0.27 -4.82 -0.4 4.04e-6 Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs11122272 0.732 rs999010 chr1:231495316 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.74 -7.08 -0.54 9.42e-11 Hemoglobin concentration; TGCT cis rs9611565 0.512 rs132784 chr22:42052363 G/A cg06634786 chr22:41940651 POLR3H 0.86 7.82 0.57 1.92e-12 Vitiligo; TGCT cis rs4654899 0.865 rs12130841 chr1:21067051 C/T cg01072550 chr1:21505969 NA -0.49 -7.85 -0.58 1.67e-12 Superior frontal gyrus grey matter volume; TGCT cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg13695892 chr22:41940480 POLR3H -0.92 -9.33 -0.64 5.22e-16 Vitiligo; TGCT cis rs35160687 0.901 rs12478653 chr2:86535394 A/C cg12542933 chr2:85804724 VAMP8 -0.39 -4.76 -0.39 5.26e-6 Night sleep phenotypes; TGCT cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs941408 1.000 rs1736177 chr19:2791624 C/T cg06609049 chr19:2785107 THOP1 0.77 7.55 0.56 8.09e-12 Total cholesterol levels; TGCT cis rs1062177 1.000 rs2915878 chr5:151149662 A/G cg12924095 chr5:151150029 G3BP1 0.35 5.07 0.41 1.41e-6 Preschool internalizing problems; TGCT cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg21951975 chr1:209979733 IRF6 0.71 6.04 0.48 1.7e-8 Cleft lip with or without cleft palate; TGCT cis rs9473924 0.542 rs9463650 chr6:50822081 C/T cg14470998 chr6:50812995 TFAP2B 1.38 8.58 0.61 3.33e-14 Body mass index; TGCT cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Vitiligo; TGCT cis rs7772486 0.875 rs1331644 chr6:146398660 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs796364 0.664 rs3106089 chr2:200884615 A/C cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT cis rs2404602 0.716 rs12438077 chr15:76863601 T/C cg22467129 chr15:76604101 ETFA -0.44 -5.05 -0.41 1.51e-6 Blood metabolite levels; TGCT cis rs35306767 0.855 rs34251037 chr10:867884 C/T cg26597838 chr10:835615 NA 0.8 12.0 0.73 1.67e-22 Eosinophil percentage of granulocytes; TGCT cis rs28595532 0.920 rs114168088 chr4:119772666 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs10949834 0.793 rs810534 chr7:73505045 A/G cg07137043 chr7:73588983 EIF4H 0.63 4.61 0.38 1.01e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs9911578 1.000 rs9897326 chr17:56902297 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs2797160 1.000 rs78602343 chr6:126019768 T/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 4.85e-9 Endometrial cancer; TGCT cis rs66731853 0.769 rs477679 chr1:20894618 A/G cg04087271 chr1:20915334 CDA 0.57 6.89 0.53 2.46e-10 Mean corpuscular volume; TGCT cis rs66561647 0.661 rs890442 chr8:128931207 G/T cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.55 0.38 1.27e-5 Hemoglobin concentration; TGCT cis rs7772486 0.875 rs9390372 chr6:146363638 G/C cg23711669 chr6:146136114 FBXO30 0.87 9.53 0.65 1.75e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs35146811 0.961 rs1880949 chr7:99722266 A/C cg13334819 chr7:99746414 C7orf59 0.82 7.34 0.55 2.49e-11 Coronary artery disease; TGCT cis rs7829975 0.688 rs6601703 chr8:8380224 A/G cg06636001 chr8:8085503 FLJ10661 0.77 7.37 0.55 2.12e-11 Mood instability; TGCT cis rs12210905 0.688 rs10456051 chr6:27463436 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.53 4.96 0.41 2.3e-6 Electroencephalogram traits; TGCT cis rs12579753 0.869 rs12366921 chr12:82223024 G/A cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs3784262 0.669 rs4646597 chr15:58300768 G/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.19 -0.49 8.05e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg02458000 chr6:26745757 NA -0.52 -4.85 -0.4 3.62e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.515 rs13142498 chr4:98792443 G/T cg18180107 chr4:99064573 C4orf37 0.54 4.74 0.39 5.8e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6500602 0.627 rs860891 chr16:4586529 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.41 -7.45 -0.56 1.42e-11 Schizophrenia; TGCT cis rs7528684 0.816 rs1977710 chr1:157693722 A/G cg17134153 chr1:157670328 FCRL3 -0.26 -4.68 -0.39 7.53e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs7731657 0.537 rs10073197 chr5:130373090 C/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs478304 0.754 rs2004649 chr11:65380916 G/A cg27068330 chr11:65405492 SIPA1 -0.81 -8.01 -0.58 7.19e-13 Acne (severe); TGCT cis rs6988636 1.000 rs16898097 chr8:124195034 G/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs806215 0.526 rs62481416 chr7:127478125 C/T cg11539674 chr7:127291444 SND1 -0.37 -4.73 -0.39 6.02e-6 Type 2 diabetes; TGCT cis rs4268898 0.686 rs2042468 chr2:24398446 A/T cg02683114 chr2:24398427 C2orf84 0.2 4.91 0.4 2.83e-6 Asthma; TGCT cis rs4319547 0.915 rs7316734 chr12:123117425 A/G cg23029597 chr12:123009494 RSRC2 -0.3 -4.92 -0.4 2.74e-6 Body mass index; TGCT cis rs16966142 0.786 rs2238533 chr16:89871344 T/C cg04287289 chr16:89883240 FANCA 0.8 5.03 0.41 1.71e-6 Caffeine consumption; TGCT cis rs74233809 1.000 rs3740390 chr10:104638480 C/T cg05855489 chr10:104503620 C10orf26 0.86 4.99 0.41 2.02e-6 Birth weight; TGCT cis rs1865760 0.827 rs9295681 chr6:25944117 T/G cg16482183 chr6:26056742 HIST1H1C 0.53 4.93 0.4 2.57e-6 Height; TGCT cis rs3749237 0.964 rs11717463 chr3:49808981 C/T cg00174179 chr3:49450293 RHOA;TCTA 0.19 4.6 0.38 1.04e-5 Resting heart rate; TGCT cis rs2204008 0.837 rs7974888 chr12:37945215 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.91 0.4 2.77e-6 Bladder cancer; TGCT cis rs4819052 0.851 rs9979545 chr21:46679805 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2469997 0.623 rs2470023 chr8:120362995 T/A cg00681363 chr8:120844660 TAF2 0.69 4.49 0.37 1.63e-5 Hypertension (SNP x SNP interaction); TGCT cis rs10927875 0.632 rs1122068 chr1:16127480 G/C cg21385522 chr1:16154831 NA -0.96 -15.62 -0.81 4.59e-31 Dilated cardiomyopathy; TGCT cis rs854765 0.693 rs8080061 chr17:17776389 C/T cg04398451 chr17:18023971 MYO15A 0.28 4.51 0.38 1.49e-5 Total body bone mineral density; TGCT cis rs11085466 1.000 rs11085466 chr19:21751811 G/C cg02997983 chr19:21646781 NA -0.62 -4.45 -0.37 1.92e-5 Colorectal or endometrial cancer; TGCT cis rs56235845 0.694 rs9313758 chr5:176773091 T/G cg17509989 chr5:176798049 RGS14 0.57 7.96 0.58 9.47e-13 Hemoglobin concentration;Hematocrit; TGCT cis rs35146811 0.961 rs11771139 chr7:99736059 C/T cg13334819 chr7:99746414 C7orf59 -0.83 -7.62 -0.56 5.61e-12 Coronary artery disease; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg10108389 chr3:44770937 ZNF501 -0.47 -4.69 -0.39 7.03e-6 Depressive symptoms; TGCT cis rs6912958 0.712 rs4498321 chr6:88339251 G/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs2204008 0.837 rs11168341 chr12:37961951 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg26818010 chr10:134567672 INPP5A -0.36 -4.69 -0.39 7.12e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11107903 1.000 rs12817989 chr12:95512389 T/A cg10621809 chr12:95840313 NA 0.7 4.61 0.38 9.89e-6 Coronary artery disease; TGCT cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.51e-14 Type 2 diabetes; TGCT cis rs55910451 0.779 rs55837307 chr10:5799144 A/G cg09234995 chr10:5726438 C10orf18 0.48 4.43 0.37 2.01e-5 Breast cancer; TGCT cis rs2204008 0.777 rs2387813 chr12:38382091 A/C cg26384229 chr12:38710491 ALG10B 0.81 7.13 0.54 7.23e-11 Bladder cancer; TGCT cis rs7017914 0.967 rs7018381 chr8:71670117 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs12497850 0.931 rs7626445 chr3:49114544 C/T cg07636037 chr3:49044803 WDR6 0.96 10.9 0.7 8.39e-20 Parkinson's disease; TGCT cis rs765787 0.530 rs12905246 chr15:45500841 C/T cg24006582 chr15:45444508 DUOX1 0.25 5.31 0.43 4.79e-7 Uric acid levels; TGCT cis rs853679 0.546 rs200950 chr6:27835772 A/G cg01031101 chr6:28227091 NKAPL -0.49 -4.66 -0.39 8.09e-6 Depression; TGCT cis rs3181245 0.641 rs3756821 chr6:24646821 C/T cg18428180 chr6:24646492 KIAA0319 0.76 7.07 0.54 1.02e-10 Colorectal or endometrial cancer; TGCT cis rs6546537 0.840 rs34743816 chr2:69813345 A/C cg10773587 chr2:69614142 GFPT1 -0.75 -6.92 -0.53 2.19e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg18252515 chr7:66147081 NA -1.24 -8.1 -0.59 4.35e-13 Diabetic kidney disease; TGCT cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.79e-5 Obesity-related traits; TGCT cis rs185694 1.000 rs202099 chr13:30896874 C/T cg07600127 chr13:30881527 KATNAL1 -0.81 -6.53 -0.51 1.53e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs2862064 1.000 rs1948760 chr5:156442784 T/A cg12943317 chr5:156479607 HAVCR1 -0.39 -5.25 -0.43 6.27e-7 Platelet count; TGCT cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg15687855 chr3:44754131 ZNF502 -0.43 -5.27 -0.43 5.98e-7 Depressive symptoms; TGCT cis rs7267979 1.000 rs2297496 chr20:25295787 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1215050 0.791 rs1215055 chr4:98865454 C/T cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.18e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9911578 1.000 rs12449365 chr17:56600660 C/G cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7617480 0.648 rs10865953 chr3:48759562 C/T cg07636037 chr3:49044803 WDR6 0.75 6.03 0.48 1.76e-8 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9928842 0.712 rs10871304 chr16:75223491 G/T cg09066997 chr16:75300724 BCAR1 0.24 4.56 0.38 1.22e-5 Alcoholic chronic pancreatitis; TGCT cis rs6665290 0.935 rs6693535 chr1:227197685 G/A cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs12048904 0.647 rs7528268 chr1:101329295 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.84 8.12 0.59 3.9e-13 Multiple sclerosis; TGCT cis rs17345786 0.861 rs79181492 chr3:101216021 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs12286929 0.607 rs10891808 chr11:115071301 T/C cg04017736 chr11:115827165 NA 0.18 4.48 0.37 1.7e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs916888 0.773 rs199447 chr17:44812188 C/T cg22968622 chr17:43663579 NA 1.3 11.87 0.73 3.46e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs34638657 0.732 rs12597534 chr16:82200276 G/T cg09439754 chr16:82129088 HSD17B2 -0.25 -4.75 -0.39 5.63e-6 Lung adenocarcinoma; TGCT cis rs524281 0.861 rs2177053 chr11:65966145 A/C cg00563793 chr11:65837595 PACS1 0.53 4.67 0.39 7.6e-6 Electroencephalogram traits; TGCT cis rs7666738 0.830 rs28615340 chr4:98896922 T/C cg05340658 chr4:99064831 C4orf37 0.51 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg04632378 chr13:21900426 NA 0.4 4.92 0.4 2.68e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs114540395 0.925 rs76197608 chr10:103392896 T/C cg03300883 chr10:102748874 C10orf2 0.42 4.63 0.38 9.24e-6 Schizophrenia; TGCT cis rs1023500 0.505 rs134899 chr22:42683030 T/G cg15557168 chr22:42548783 NA -0.2 -4.79 -0.4 4.6e-6 Schizophrenia; TGCT cis rs57590327 0.583 rs13062245 chr3:81833718 G/T cg07356753 chr3:81810745 GBE1 -0.73 -6.73 -0.52 5.57e-10 Extraversion; TGCT cis rs11148252 0.574 rs7139495 chr13:53283318 A/G cg00495681 chr13:53174319 NA 0.62 6.27 0.49 5.35e-9 Lewy body disease; TGCT cis rs10883723 0.810 rs2281879 chr10:104268877 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.85 9.06 0.63 2.36e-15 Allergic disease (asthma, hay fever or eczema); TGCT cis rs17152411 0.793 rs12569669 chr10:126592671 A/G cg07906193 chr10:126599966 NA 0.42 5.16 0.42 9.36e-7 Height; TGCT cis rs7267979 0.932 rs6037125 chr20:25463382 G/A cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2486012 1.000 rs61770291 chr1:44383123 A/G cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.816 rs6037158 chr20:25595466 C/A cg14121845 chr20:25566513 NINL 0.45 4.69 0.39 7.14e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6840360 0.967 rs6535812 chr4:152599374 C/A cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs9348796 chr6:28126202 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs3892630 0.588 rs8106748 chr19:33282797 G/A cg22980127 chr19:33182716 NUDT19 0.74 6.09 0.48 1.3e-8 Red blood cell traits; TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg02073558 chr3:44770973 ZNF501 0.58 5.68 0.45 8.89e-8 Depressive symptoms; TGCT cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg11644478 chr21:40555479 PSMG1 1.03 11.12 0.71 2.32e-20 Cognitive function; TGCT cis rs2354432 0.882 rs11576360 chr1:146740576 G/A cg25205988 chr1:146714368 CHD1L 1.34 10.54 0.69 6.14e-19 Mitochondrial DNA levels; TGCT cis rs1372520 0.684 rs2737010 chr4:90746466 G/A cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg06753367 chr22:24256600 NA -0.24 -4.54 -0.38 1.31e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4975616 0.839 rs2447853 chr5:1333077 A/G cg06550200 chr5:1325588 CLPTM1L -0.32 -4.77 -0.39 5.09e-6 Lung cancer; TGCT cis rs7267979 0.873 rs7453 chr20:25207074 A/G cg14121845 chr20:25566513 NINL 0.47 5.15 0.42 1e-6 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1496653 0.602 rs13090335 chr3:23463722 A/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2070488 1.000 rs17733640 chr3:38446742 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 9.06e-17 Electrocardiographic conduction measures; TGCT cis rs8031584 0.663 rs1917421 chr15:31187663 C/T cg08109568 chr15:31115862 NA -0.35 -4.79 -0.4 4.66e-6 Huntington's disease progression; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg24675658 chr1:53192096 ZYG11B 0.7 8.03 0.58 6.54e-13 Monocyte count; TGCT cis rs651907 0.557 rs7629753 chr3:101371922 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.89 -11.14 -0.71 2.09e-20 Colorectal cancer; TGCT cis rs4973397 0.883 rs4973392 chr2:232286552 G/A cg09339159 chr2:232260559 B3GNT7 0.55 4.54 0.38 1.3e-5 Anti-saccade response; TGCT cis rs7191700 0.511 rs8043625 chr16:11361895 C/G cg00044050 chr16:11439710 C16orf75 -0.81 -8.38 -0.6 9.95e-14 Multiple sclerosis; TGCT cis rs72615157 0.645 rs76281814 chr7:99846414 T/C cg00814883 chr7:100076585 TSC22D4 -0.59 -5.7 -0.46 8.45e-8 Lung function (FEV1/FVC); TGCT cis rs7666738 0.830 rs9884501 chr4:98893721 A/C cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.81e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs73001065 0.818 rs58847337 chr19:19726022 G/A cg03709012 chr19:19516395 GATAD2A 1.08 5.32 0.43 4.76e-7 LDL cholesterol; TGCT cis rs10479542 0.766 rs7733389 chr5:178974997 C/T cg00080972 chr5:178986291 RUFY1 0.46 5.59 0.45 1.36e-7 Lung cancer; TGCT cis rs7267979 0.586 rs6050439 chr20:25192331 T/C cg14121845 chr20:25566513 NINL 0.45 4.86 0.4 3.51e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11123170 0.529 rs1015755 chr2:113968307 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.58 4.69 0.39 7.01e-6 Renal function-related traits (BUN); TGCT cis rs2404602 0.716 rs12441247 chr15:76812316 T/C cg22467129 chr15:76604101 ETFA -0.56 -6.65 -0.51 8.35e-10 Blood metabolite levels; TGCT cis rs149866169 1 rs149866169 chr6:27441723 T/A cg08798685 chr6:27730294 NA -0.38 -4.57 -0.38 1.15e-5 Neuroticism (multi-trait analysis);Lung cancer in ever smokers;Subjective well-being (multi-trait analysis);Lung cancer;Squamous cell lung carcinoma; TGCT trans rs208520 0.690 rs12213581 chr6:66735818 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs9549367 0.756 rs3861723 chr13:113910926 A/G cg18105134 chr13:113819100 PROZ -0.31 -5.42 -0.44 3.01e-7 Platelet distribution width; TGCT cis rs763121 0.853 rs7289577 chr22:39042214 C/G cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs72945132 0.882 rs7116059 chr11:70159690 G/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs950776 0.790 rs2067808 chr15:78911780 G/A cg06917634 chr15:78832804 PSMA4 0.65 5.03 0.41 1.68e-6 Sudden cardiac arrest; TGCT cis rs2274459 0.500 rs34517899 chr6:33635309 C/G cg00898486 chr6:34006557 GRM4 0.32 4.96 0.41 2.31e-6 Obesity (extreme); TGCT cis rs6089829 0.925 rs13041507 chr20:61666180 T/C cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs2239547 0.657 rs4687672 chr3:52880543 G/A cg10802521 chr3:52805072 NEK4 -0.65 -6.12 -0.48 1.16e-8 Schizophrenia; TGCT cis rs763014 0.966 rs35642938 chr16:642249 T/C cg00908189 chr16:619842 PIGQ 0.86 10.29 0.68 2.54e-18 Height; TGCT cis rs7267979 0.528 rs34485039 chr20:25583763 G/T cg03522245 chr20:25566470 NINL -0.44 -4.57 -0.38 1.18e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg15659132 chr6:26577336 NA 0.86 11.69 0.72 9.65e-22 Intelligence (multi-trait analysis); TGCT cis rs7027203 1.000 rs7856374 chr9:96529791 G/A cg14396892 chr9:96623032 NA 0.23 4.54 0.38 1.33e-5 DNA methylation (variation); TGCT cis rs10744422 0.920 rs10773657 chr12:123327900 C/A cg25930673 chr12:123319894 HIP1R -0.85 -5.01 -0.41 1.86e-6 Schizophrenia; TGCT cis rs546131 0.642 rs2915186 chr11:34851183 C/T cg06937548 chr11:34938143 PDHX;APIP 0.52 4.5 0.37 1.52e-5 Lung disease severity in cystic fibrosis; TGCT cis rs950027 0.620 rs1145077 chr15:45683795 A/C cg14582100 chr15:45693742 SPATA5L1 -0.48 -5.86 -0.47 3.88e-8 Response to fenofibrate (adiponectin levels); TGCT trans rs208515 0.556 rs1872309 chr6:66660432 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.77 7.97 0.58 9.03e-13 Exhaled nitric oxide levels; TGCT cis rs7666738 0.680 rs11726233 chr4:99079773 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.37 0.43 3.81e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7954584 0.567 rs11043251 chr12:122373279 C/T cg13699009 chr12:122356056 WDR66 0.29 5.72 0.46 7.44e-8 Mean corpuscular volume; TGCT trans rs751984 0.706 rs3802951 chr11:61273700 T/C cg03305746 chr2:106927199 NA -0.58 -6.8 -0.52 3.93e-10 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs9650657 0.513 rs4841459 chr8:10782442 A/C cg27411982 chr8:10470053 RP1L1 -0.23 -4.86 -0.4 3.47e-6 Neuroticism; TGCT cis rs1862618 0.525 rs2662016 chr5:56269047 A/G cg18230493 chr5:56204884 C5orf35 0.72 5.56 0.45 1.59e-7 Initial pursuit acceleration; TGCT cis rs2777491 0.574 rs2730056 chr15:41735785 A/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -17.17 -0.84 1.44e-34 Ulcerative colitis; TGCT cis rs2239547 0.522 rs9846976 chr3:53007995 T/C cg10802521 chr3:52805072 NEK4 -0.6 -5.43 -0.44 2.88e-7 Schizophrenia; TGCT cis rs9534288 0.577 rs2897029 chr13:46682821 T/C cg15192986 chr13:46630673 CPB2 -0.51 -6.11 -0.48 1.17e-8 Blood protein levels; TGCT cis rs853679 0.517 rs9393888 chr6:28059217 G/C cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs9911578 1.000 rs2531729 chr17:56539890 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.28 0.64 7.12e-16 Intelligence (multi-trait analysis); TGCT cis rs1784581 0.674 rs1784592 chr6:162387365 T/A cg17173639 chr6:162384350 PARK2 -0.47 -8.16 -0.59 3.15e-13 Itch intensity from mosquito bite; TGCT cis rs245880 0.740 rs245885 chr7:29188554 A/G cg17163760 chr7:29186267 CPVL -0.44 -5.54 -0.45 1.73e-7 Warfarin maintenance dose; TGCT cis rs6669919 0.570 rs34293509 chr1:211690673 C/A cg25617285 chr1:211431773 RCOR3 -0.39 -4.44 -0.37 1.93e-5 Intelligence (multi-trait analysis); TGCT cis rs11644362 1.000 rs12918494 chr16:12988455 C/T cg06890432 chr16:12997467 SHISA9 -0.61 -6.7 -0.52 6.46e-10 Positive affect;Subjective well-being; TGCT cis rs10504229 0.683 rs903706 chr8:58128134 T/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs782590 0.537 rs12619903 chr2:55884106 T/A cg18811423 chr2:55921094 PNPT1 -0.62 -5.23 -0.43 6.84e-7 Metabolic syndrome; TGCT cis rs6748734 1.000 rs6748734 chr2:241837452 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -6.27 -0.49 5.35e-9 Urinary metabolites; TGCT cis rs35883536 0.588 rs72977389 chr1:101107053 A/C cg06223162 chr1:101003688 GPR88 0.34 5.67 0.45 9.44e-8 Monocyte count; TGCT cis rs12615966 0.651 rs58796108 chr2:105408088 T/A cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs56036086 0.887 rs73187244 chr22:50625271 T/C cg01548456 chr22:50352384 NA 0.36 5.16 0.42 9.67e-7 Platelet count;Plateletcrit; TGCT cis rs6969780 1.000 rs6969780 chr7:27159136 G/C cg04321618 chr7:27170880 HOXA4 0.55 4.9 0.4 2.97e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs5769707 0.609 rs2007024 chr22:49988815 C/T cg05373962 chr22:49881684 NA -0.29 -5.12 -0.42 1.13e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1218582 0.772 rs4845400 chr1:154872523 C/T cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg03351412 chr1:154909251 PMVK 0.52 4.92 0.4 2.66e-6 Prostate cancer; TGCT cis rs6089584 1.000 rs6089581 chr20:60562394 G/A cg16423285 chr20:60520624 NA -0.52 -5.45 -0.44 2.6e-7 Body mass index; TGCT cis rs6424115 1.000 rs6424115 chr1:24153231 A/G cg15997130 chr1:24165203 NA -0.9 -10.23 -0.68 3.51e-18 Immature fraction of reticulocytes; TGCT cis rs9486715 0.867 rs9373887 chr6:96957004 C/T cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg13393036 chr8:95962371 TP53INP1 0.6 7.7 0.57 3.67e-12 Type 2 diabetes; TGCT cis rs7312933 0.618 rs12366848 chr12:42682215 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.57 5.4 0.44 3.2e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10493773 1.000 rs3767163 chr1:86121895 T/G cg17807903 chr1:86174739 ZNHIT6 -0.37 -4.69 -0.39 7.01e-6 Urate levels in overweight individuals; TGCT cis rs2070488 0.804 rs7372452 chr3:38444298 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.77 7.49 0.56 1.12e-11 Electrocardiographic conduction measures; TGCT cis rs514406 0.505 rs387436 chr1:53179376 C/T cg16325326 chr1:53192061 ZYG11B -0.85 -12.13 -0.74 8.13e-23 Monocyte count; TGCT cis rs13242816 1.000 rs35538349 chr7:116117896 C/T cg02799643 chr7:116139180 CAV2 -0.49 -5.61 -0.45 1.27e-7 P wave duration; TGCT cis rs7772486 0.806 rs7740785 chr6:146171299 C/A cg05347473 chr6:146136440 FBXO30 0.54 5.09 0.42 1.27e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7769051 1.000 rs12204027 chr6:133122831 A/G cg07930552 chr6:133119739 C6orf192 0.94 5.04 0.41 1.6e-6 Type 2 diabetes nephropathy; TGCT cis rs910316 1.000 rs12589376 chr14:75561152 C/T cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs6558530 0.799 rs62477060 chr8:1706498 A/T cg09410841 chr8:1729607 CLN8 0.9 10.08 0.67 8.29e-18 Systolic blood pressure; TGCT cis rs6570726 0.935 rs407721 chr6:145871354 A/C cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg13397359 chr6:42928475 GNMT 0.73 6.54 0.51 1.45e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2180341 0.782 rs6912750 chr6:127723081 A/T cg27446573 chr6:127587934 RNF146 0.8 7.08 0.54 9.53e-11 Breast cancer; TGCT cis rs2204008 0.630 rs12306932 chr12:38242029 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs3782123 1.000 rs3782123 chr11:205198 C/A cg18336825 chr11:236787 PSMD13;SIRT3 -0.51 -4.65 -0.39 8.41e-6 Glycated hemoglobin levels;Red cell distribution width; TGCT cis rs1023500 0.573 rs2269524 chr22:42475703 T/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Schizophrenia; TGCT cis rs9303542 0.559 rs1042818 chr17:46620111 T/C cg25032089 chr17:46643351 HOXB3 0.56 5.27 0.43 5.97e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs9291683 0.546 rs13120348 chr4:10053155 C/G cg00071950 chr4:10020882 SLC2A9 -0.58 -6.53 -0.51 1.52e-9 Bone mineral density; TGCT cis rs826838 1.000 rs860400 chr12:39081279 A/G cg13010199 chr12:38710504 ALG10B -0.59 -4.89 -0.4 3e-6 Heart rate; TGCT cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg02458000 chr6:26745757 NA 0.51 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs11209002 0.614 rs6670381 chr1:67562106 G/T cg02640540 chr1:67518911 SLC35D1 0.61 5.09 0.42 1.29e-6 Crohn's disease; TGCT trans rs7726839 0.540 rs72705097 chr5:655067 G/A cg11887960 chr12:57824829 NA 1.16 9.4 0.65 3.51e-16 Obesity-related traits; TGCT cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs7412746 0.611 rs4970931 chr1:150910727 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs2204008 0.657 rs8186888 chr12:38334260 T/G cg26384229 chr12:38710491 ALG10B 0.61 5.63 0.45 1.15e-7 Bladder cancer; TGCT cis rs1372520 0.684 rs1811442 chr4:90747751 C/T cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs58722170 0.659 rs12023270 chr1:38086578 A/G cg17933807 chr1:38061675 GNL2 0.85 8.73 0.62 1.42e-14 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6500602 0.702 rs1051308 chr16:4560301 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.31 -5.71 -0.46 7.88e-8 Schizophrenia; TGCT cis rs854765 0.565 rs854768 chr17:18018806 T/C cg04398451 chr17:18023971 MYO15A -0.39 -6.75 -0.52 5e-10 Total body bone mineral density; TGCT cis rs1801251 1.000 rs1867778 chr2:233679644 C/T cg25237894 chr2:233734115 C2orf82 -0.3 -5.44 -0.44 2.74e-7 Coronary artery disease; TGCT cis rs6674176 0.660 rs6801 chr1:44396646 C/G cg12908607 chr1:44402522 ARTN 0.72 9.08 0.63 2.12e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs4563143 0.704 rs16961809 chr19:29226299 C/T cg14983838 chr19:29218262 NA 0.81 7.62 0.56 5.68e-12 Methadone dose in opioid dependence; TGCT cis rs7267979 0.528 rs6076366 chr20:25564626 G/T cg03522245 chr20:25566470 NINL -0.44 -4.59 -0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3749237 0.576 rs4241406 chr3:49600426 C/T cg02487422 chr3:49467188 NICN1 0.56 5.53 0.44 1.81e-7 Resting heart rate; TGCT trans rs1005277 0.579 rs2474594 chr10:38426661 G/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs950776 0.620 rs7181405 chr15:78948152 A/G cg21242079 chr15:79101063 ADAMTS7 -0.3 -4.91 -0.4 2.77e-6 Sudden cardiac arrest; TGCT cis rs79349575 0.756 rs2291726 chr17:47039254 T/C cg07967210 chr17:47022446 SNF8 -0.44 -5.94 -0.47 2.68e-8 Type 2 diabetes; TGCT cis rs8032315 0.965 rs1894400 chr15:91428955 C/T cg05211768 chr15:91427848 FES 0.51 5.11 0.42 1.2e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs11648796 0.757 rs6600231 chr16:766485 A/G cg00908189 chr16:619842 PIGQ -0.66 -5.41 -0.44 3.14e-7 Height; TGCT cis rs2130392 0.962 rs35613786 chr4:185625657 A/G cg14471096 chr4:185570637 CCDC111;CASP3 -0.56 -5.06 -0.41 1.49e-6 Kawasaki disease; TGCT trans rs2727020 0.930 rs1164686 chr11:49291822 C/T cg03929089 chr4:120376271 NA 0.71 7.73 0.57 3.16e-12 Coronary artery disease; TGCT cis rs6988636 0.901 rs16898076 chr8:124187721 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1997103 1.000 rs12532070 chr7:55407698 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1371867 0.846 rs1660330 chr8:101305015 T/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs41271951 0.512 rs79122717 chr1:151093526 G/A cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs9611565 0.649 rs5758442 chr22:42133060 T/C cg17554472 chr22:41940697 POLR3H 0.43 4.54 0.38 1.31e-5 Vitiligo; TGCT cis rs1971762 0.762 rs7976793 chr12:54073069 G/T cg22997177 chr12:54070527 ATP5G2 -0.33 -4.47 -0.37 1.76e-5 Height; TGCT cis rs1541995 0.964 rs12917406 chr15:96298442 A/G cg00882281 chr15:96346592 NA 0.29 4.77 0.39 5.12e-6 Photic sneeze reflex; TGCT cis rs174601 0.861 rs174580 chr11:61606642 A/G cg01500311 chr11:61656094 FADS3 -0.33 -5.8 -0.46 5.23e-8 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs597539 0.615 rs583182 chr11:68678634 C/T cg06028808 chr11:68637592 NA 0.53 6.87 0.53 2.75e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.72 -0.39 6.33e-6 Prudent dietary pattern; TGCT cis rs11247915 0.540 rs11582416 chr1:26677721 A/G cg23732845 chr1:26663426 AIM1L 0.35 4.68 0.39 7.43e-6 Obesity-related traits; TGCT cis rs2486288 0.656 rs11632778 chr15:45551056 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs7020830 0.867 rs7852593 chr9:37332380 A/T cg14294708 chr9:37120828 ZCCHC7 1.24 16.92 0.84 5.14e-34 Schizophrenia; TGCT cis rs62244186 0.627 rs3935212 chr3:44460954 G/A cg10263370 chr3:44754102 ZNF502 -0.38 -4.58 -0.38 1.1e-5 Depressive symptoms; TGCT cis rs3803170 0.513 rs7299142 chr12:111829513 G/A cg10833066 chr12:111807467 FAM109A 0.36 5.41 0.44 3.09e-7 Mean corpuscular hemoglobin; TGCT cis rs344364 0.602 rs12719796 chr16:1921197 A/G cg01422476 chr16:1922425 C16orf73 -0.46 -4.45 -0.37 1.92e-5 Glomerular filtration rate in chronic kidney disease; TGCT cis rs751728 1.000 rs751728 chr6:33764033 C/T cg13859433 chr6:33739653 LEMD2 -0.39 -7.1 -0.54 8.43e-11 Crohn's disease; TGCT cis rs3820068 0.705 rs57440988 chr1:15879034 T/C cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 15.79 0.82 1.81e-31 Prudent dietary pattern; TGCT cis rs10028773 0.700 rs7671797 chr4:120248157 A/G cg09307838 chr4:120376055 NA 0.61 5.92 0.47 3.01e-8 Educational attainment; TGCT cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg13695892 chr22:41940480 POLR3H 0.93 9.17 0.64 1.31e-15 Vitiligo; TGCT cis rs56399783 0.708 rs56208415 chr7:2813806 G/A cg19731401 chr7:2775893 GNA12 0.35 4.9 0.4 2.97e-6 Childhood ear infection; TGCT cis rs7226408 0.857 rs56308574 chr18:34586293 C/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6964587 0.692 rs10271430 chr7:91710466 G/C cg17063962 chr7:91808500 NA 0.74 6.96 0.53 1.75e-10 Breast cancer; TGCT cis rs8031584 0.958 rs7176569 chr15:31244495 G/T cg08704250 chr15:31115839 NA 0.36 4.96 0.41 2.29e-6 Huntington's disease progression; TGCT cis rs2549003 0.674 rs960757 chr5:131826310 G/A cg02551604 chr5:131831745 NA -0.85 -10.74 -0.69 1.98e-19 Asthma (sex interaction); TGCT cis rs986417 0.901 rs12883305 chr14:61006690 A/G cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs9916302 0.861 rs9903363 chr17:37499604 C/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs8038465 0.874 rs2291011 chr15:74000839 G/A cg15420318 chr15:73925796 NPTN 0.57 5.11 0.42 1.17e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs478304 0.654 rs6591187 chr11:65460086 C/G cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.79e-13 Acne (severe); TGCT cis rs11170631 0.504 rs12817180 chr12:54035448 A/G cg16917193 chr12:54089295 NA 1.04 11.51 0.72 2.68e-21 Height; TGCT cis rs79387448 0.810 rs76229479 chr2:103123912 A/C cg09003973 chr2:102972529 NA 1.02 6.11 0.48 1.19e-8 Gut microbiota (bacterial taxa); TGCT cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs739496 0.653 rs10744773 chr12:112086810 C/A cg10833066 chr12:111807467 FAM109A 0.36 5.22 0.42 7.28e-7 Platelet count; TGCT cis rs739496 0.947 rs7299849 chr12:111855461 A/T cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs7666738 0.791 rs2865953 chr4:99040319 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6701037 0.566 rs729675 chr1:175136946 T/C cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs16867321 0.671 rs10189871 chr2:181515623 G/T cg23363182 chr2:181467187 NA -0.44 -4.59 -0.38 1.09e-5 Obesity; TGCT cis rs7914558 0.933 rs10786729 chr10:104719378 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.99 -0.41 1.97e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4253772 0.530 rs11704350 chr22:46671507 C/T cg24881330 chr22:46731750 TRMU 0.92 4.55 0.38 1.27e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs42648 0.748 rs6972119 chr7:89894008 T/C cg25739043 chr7:89950458 NA -0.63 -6.12 -0.48 1.16e-8 Homocysteine levels; TGCT cis rs4237845 0.537 rs11172367 chr12:58272486 T/G cg23860436 chr12:58378763 NA 0.33 4.45 0.37 1.86e-5 Intelligence (multi-trait analysis); TGCT cis rs7760949 0.548 rs280151 chr6:13942831 C/G cg27413430 chr6:13925136 RNF182 -0.56 -4.56 -0.38 1.21e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs7582180 0.715 rs1866198 chr2:100917739 C/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.89e-7 Intelligence (multi-trait analysis); TGCT cis rs1403694 0.695 rs67173199 chr3:186432858 G/A cg12454167 chr3:186435060 KNG1 0.5 8.56 0.61 3.65e-14 Blood protein levels; TGCT cis rs597539 0.652 rs516425 chr11:68715675 G/A cg06028808 chr11:68637592 NA 0.55 7.3 0.55 3.1e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4665809 0.941 rs3177055 chr2:26359315 G/A cg22920501 chr2:26401640 FAM59B -0.71 -5.88 -0.47 3.63e-8 Gut microbiome composition (summer); TGCT cis rs3829109 0.504 rs11145890 chr9:139293851 C/G cg13741927 chr9:139327495 INPP5E -0.24 -5.18 -0.42 8.84e-7 Peak insulin response;Acute insulin response; TGCT cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.45 0.44 2.66e-7 Height; TGCT cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg24675658 chr1:53192096 ZYG11B 0.74 8.65 0.61 2.2e-14 Monocyte count; TGCT cis rs12477438 0.798 rs2084987 chr2:99587885 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs71435601 0.628 rs312979 chr2:21377705 A/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs11098499 0.644 rs7676296 chr4:120555687 A/G cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs8031584 0.578 rs1088473 chr15:31139298 A/G cg08704250 chr15:31115839 NA 0.43 6.31 0.49 4.47e-9 Huntington's disease progression; TGCT cis rs7119038 0.774 rs11217038 chr11:118677355 G/A cg19308663 chr11:118741387 NA 0.31 6.42 0.5 2.65e-9 Sjögren's syndrome; TGCT cis rs614226 0.935 rs3887875 chr12:120895749 A/G cg10072921 chr12:121022843 NA 0.45 4.69 0.39 7.09e-6 Type 1 diabetes nephropathy; TGCT trans rs6089829 0.962 rs1060490 chr20:61665871 A/G cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT trans rs62103177 0.810 rs62096746 chr18:77619556 T/A cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs80262450 1 rs80262450 chr18:12818922 G/A cg23598886 chr18:12777645 NA -0.61 -4.5 -0.37 1.52e-5 Inflammatory bowel disease;Crohn's disease; TGCT trans rs2727020 0.658 rs1851992 chr11:49438110 C/T cg03929089 chr4:120376271 NA -0.74 -8.55 -0.61 3.78e-14 Coronary artery disease; TGCT cis rs2836950 0.565 rs4816617 chr21:40540690 T/C cg06238570 chr21:40685208 BRWD1 -0.6 -6.22 -0.49 6.89e-9 Menarche (age at onset); TGCT cis rs2204008 0.818 rs1589389 chr12:38416041 G/A cg13010199 chr12:38710504 ALG10B -0.55 -4.47 -0.37 1.76e-5 Bladder cancer; TGCT cis rs2229238 0.868 rs12408461 chr1:154512710 T/C cg13067139 chr1:155221277 FAM189B 0.2 4.46 0.37 1.85e-5 Coronary heart disease; TGCT cis rs12681287 0.640 rs13253515 chr8:87458596 T/A cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs4077468 1.000 rs11801695 chr1:205916175 A/C cg14982357 chr1:205744203 RAB7L1 0.44 4.45 0.37 1.91e-5 Cystic fibrosis-related diabetes; TGCT cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg08219700 chr8:58056026 NA 0.39 4.73 0.39 5.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs6545883 0.831 rs2592356 chr2:61810428 G/C cg15711740 chr2:61764176 XPO1 -0.6 -5.76 -0.46 6.27e-8 Tuberculosis; TGCT cis rs9467711 0.524 rs13216484 chr6:26762087 C/T cg16898833 chr6:26189333 HIST1H4D 1.27 6.03 0.48 1.76e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs453301 0.506 rs686189 chr8:8623637 A/G cg06636001 chr8:8085503 FLJ10661 -0.52 -4.51 -0.38 1.46e-5 Joint mobility (Beighton score); TGCT cis rs137603 0.901 rs137612 chr22:39698010 A/G cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -5.1 -0.42 1.26e-6 Primary biliary cholangitis; TGCT cis rs11098499 0.863 rs13134665 chr4:120426430 T/C cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.28e-9 Corneal astigmatism; TGCT cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg11644478 chr21:40555479 PSMG1 -0.63 -5.92 -0.47 2.93e-8 Cognitive function; TGCT cis rs11785400 0.793 rs4301430 chr8:143737416 A/G cg24634471 chr8:143751801 JRK 0.54 5.44 0.44 2.77e-7 Schizophrenia; TGCT cis rs8180040 0.701 rs62248439 chr3:46996448 A/G cg27129171 chr3:47204927 SETD2 -0.71 -8.9 -0.62 5.58e-15 Colorectal cancer; TGCT cis rs4629710 0.568 rs67021539 chr6:131552900 A/G cg12606694 chr6:131520996 AKAP7 0.39 4.57 0.38 1.17e-5 Multiple myeloma (IgH translocation); TGCT cis rs9291683 1.000 rs9291683 chr4:10324160 C/T cg11266682 chr4:10021025 SLC2A9 0.48 5.65 0.45 1.04e-7 Bone mineral density; TGCT cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg09904177 chr6:26538194 HMGN4 0.68 6.27 0.49 5.41e-9 Intelligence (multi-trait analysis); TGCT cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg27286337 chr10:134555280 INPP5A 0.46 5.55 0.45 1.62e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9910055 0.529 rs228767 chr17:42188311 C/G cg13607699 chr17:42295918 UBTF -0.66 -5.46 -0.44 2.51e-7 Total body bone mineral density; TGCT cis rs7474896 0.583 rs10740950 chr10:38003496 C/T cg13720705 chr10:37990370 NA 0.34 4.9 0.4 2.9e-6 Obesity (extreme); TGCT cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs6840360 0.642 rs28666858 chr4:152416382 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs425277 0.585 rs3107157 chr1:2061969 A/G cg03732007 chr1:2071316 PRKCZ -0.25 -5.73 -0.46 7.25e-8 Height; TGCT cis rs350251 0.868 rs350232 chr16:12190947 G/C cg02910054 chr16:12241554 SNX29 0.37 4.74 0.39 5.66e-6 Intelligence (multi-trait analysis); TGCT cis rs3784262 0.904 rs4646616 chr15:58261349 G/A cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.78 -0.57 2.39e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6088580 0.634 rs6120642 chr20:33012531 A/G cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs6835098 1.000 rs10031414 chr4:174084953 A/C cg08422745 chr4:174089978 GALNT7 -0.94 -11.2 -0.71 1.48e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs597539 0.617 rs669659 chr11:68635623 G/C cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs3780486 0.846 rs7864705 chr9:33140352 A/C cg20290983 chr6:43655470 MRPS18A 1.19 14.6 0.8 1.02e-28 IgG glycosylation; TGCT cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg06221963 chr1:154839813 KCNN3 0.48 5.97 0.47 2.33e-8 Schizophrenia; TGCT cis rs1008375 1.000 rs55939327 chr4:17642937 T/A cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2120019 0.938 rs59094290 chr15:75308561 G/T cg09165964 chr15:75287851 SCAMP5 -1.17 -10.03 -0.67 1.05e-17 Blood trace element (Zn levels); TGCT cis rs9303542 0.625 rs7222242 chr17:46565486 C/A cg25032089 chr17:46643351 HOXB3 0.58 5.96 0.47 2.45e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs3027009 0.881 rs56184975 chr1:159149253 G/T cg27303699 chr1:158224869 CD1A -0.4 -4.59 -0.38 1.07e-5 Lean body mass and age at menarche (combined); TGCT cis rs586688 0.625 rs601757 chr1:201657508 A/G cg07139329 chr1:201708558 NAV1 -0.48 -5.18 -0.42 8.83e-7 Obesity-related traits; TGCT cis rs58788809 1 rs58788809 chr9:5038596 ATTT/A cg02405213 chr9:5042618 JAK2 -0.57 -7.2 -0.54 5.12e-11 Platelet count; TGCT cis rs7727544 0.684 rs274561 chr5:131719228 A/C cg24060327 chr5:131705240 SLC22A5 -0.61 -6.68 -0.51 7.09e-10 Blood metabolite levels; TGCT cis rs7027203 0.759 rs10761282 chr9:96586175 G/A cg14396892 chr9:96623032 NA -0.29 -5.97 -0.47 2.3e-8 DNA methylation (variation); TGCT cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg00343986 chr7:65444356 GUSB 0.26 5.95 0.47 2.56e-8 Calcium levels; TGCT cis rs7752195 0.643 rs116090114 chr6:25257785 C/T cg16898833 chr6:26189333 HIST1H4D 0.99 4.81 0.4 4.21e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs77669868 0.929 rs3782004 chr11:114070250 T/C cg01914181 chr11:114070210 ZBTB16 0.33 5.73 0.46 7.25e-8 Monocyte percentage of white cells; TGCT cis rs854765 0.624 rs9891957 chr17:17744439 G/A cg09796270 chr17:17721594 SREBF1 -0.24 -4.49 -0.37 1.59e-5 Total body bone mineral density; TGCT cis rs4076764 0.958 rs6688997 chr1:163411562 G/A cg24596788 chr1:163392923 NA -0.17 -4.83 -0.4 3.96e-6 Motion sickness; TGCT cis rs4891159 0.548 rs2554830 chr18:74127702 A/G cg24786174 chr18:74118243 ZNF516 0.67 13.58 0.77 2.65e-26 Longevity; TGCT cis rs9634489 0.560 rs601674 chr13:97081460 T/G cg11411106 chr13:97107445 HS6ST3 -0.27 -5.07 -0.41 1.42e-6 Body mass index; TGCT cis rs9902453 0.791 rs2729451 chr17:28131334 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -7.18 -0.54 5.76e-11 Coffee consumption (cups per day); TGCT cis rs2760061 0.819 rs3094913 chr1:228206980 T/C cg02753203 chr1:228287806 NA 0.3 5.71 0.46 8.06e-8 Diastolic blood pressure; TGCT trans rs208520 0.690 rs207081 chr6:66773742 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -11.08 -0.71 3.01e-20 Exhaled nitric oxide output; TGCT cis rs75686122 0.892 rs1895899 chr8:104602625 G/T cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs7100689 0.784 rs7081903 chr10:82162509 T/C cg01528321 chr10:82214614 TSPAN14 0.87 8.71 0.62 1.62e-14 Post bronchodilator FEV1; TGCT cis rs7412746 0.634 rs72704658 chr1:150833010 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 4.83 0.4 3.97e-6 Melanoma; TGCT cis rs3820068 0.581 rs56128111 chr1:15928948 T/G cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs2153535 0.580 rs1414345 chr6:8471537 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1062177 0.950 rs892005 chr5:151180621 A/G cg00977110 chr5:151150581 G3BP1 0.4 4.5 0.38 1.51e-5 Preschool internalizing problems; TGCT cis rs7769051 1.000 rs3813347 chr6:133119778 G/A cg22852734 chr6:133119734 C6orf192 1.22 6.9 0.53 2.34e-10 Type 2 diabetes nephropathy; TGCT cis rs1580019 0.563 rs34319173 chr7:32585904 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.6 4.97 0.41 2.17e-6 Cognitive ability; TGCT cis rs4722166 0.573 rs35436671 chr7:22775508 G/A cg26061582 chr7:22766209 IL6 0.59 7.61 0.56 5.85e-12 Lung cancer; TGCT cis rs3808502 0.585 rs4549730 chr8:11239078 T/G cg21775007 chr8:11205619 TDH -0.68 -6.6 -0.51 1.08e-9 Neuroticism; TGCT cis rs2153535 0.601 rs9393030 chr6:8516489 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs8077577 1.000 rs62073605 chr17:18066791 C/T cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs9560113 0.960 rs4773378 chr13:112174154 G/A cg14154082 chr13:112174009 NA 0.34 4.67 0.39 7.79e-6 Menarche (age at onset); TGCT cis rs2115630 1.000 rs2879828 chr15:85361977 G/T cg11189052 chr15:85197271 WDR73 -0.63 -6.03 -0.48 1.71e-8 P wave terminal force; TGCT cis rs6582630 0.555 rs11180986 chr12:38264486 G/A cg26384229 chr12:38710491 ALG10B -0.52 -4.52 -0.38 1.44e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs2795502 1.000 rs3121279 chr10:43378449 T/A cg20628663 chr10:43360327 NA 0.43 6.2 0.49 7.57e-9 Blood protein levels; TGCT cis rs6545883 0.929 rs2593626 chr2:61665184 C/A cg15711740 chr2:61764176 XPO1 -0.56 -5.07 -0.41 1.42e-6 Tuberculosis; TGCT cis rs7666738 0.830 rs7679299 chr4:99057620 C/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1799949 0.931 rs34474989 chr17:41445410 A/T cg05368731 chr17:41323189 NBR1 1.16 14.14 0.79 1.28e-27 Menopause (age at onset); TGCT cis rs2762353 0.935 rs11754288 chr6:25776949 G/A cg03517284 chr6:25882590 NA 0.5 5.19 0.42 8.42e-7 Blood metabolite levels; TGCT cis rs533581 0.873 rs579740 chr16:88973937 A/G cg16701003 chr16:89028210 CBFA2T3 -0.39 -5.61 -0.45 1.26e-7 Social autistic-like traits; TGCT cis rs7914558 0.902 rs7092200 chr10:104844872 T/C cg15744005 chr10:104629667 AS3MT -0.39 -4.75 -0.39 5.57e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7617773 0.780 rs4511916 chr3:48350366 G/A cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs1348850 0.789 rs13027959 chr2:178275887 G/A cg22681709 chr2:178499509 PDE11A -0.35 -4.73 -0.39 6.08e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs981844 0.714 rs6822142 chr4:154683524 C/T cg14289246 chr4:154710475 SFRP2 -0.89 -8.19 -0.59 2.73e-13 Response to statins (LDL cholesterol change); TGCT cis rs7511006 1.000 rs7290710 chr22:50677454 C/T cg16473166 chr22:50639996 SELO 0.61 5.95 0.47 2.51e-8 Obesity-related traits; TGCT cis rs10504229 0.906 rs2270608 chr8:58194688 T/C cg22535103 chr8:58192502 C8orf71 -0.39 -4.5 -0.37 1.54e-5 Developmental language disorder (linguistic errors); TGCT cis rs950169 0.840 rs2896002 chr15:84945121 A/G cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs6426558 0.559 rs7549520 chr1:227258858 G/C cg10327440 chr1:227177885 CDC42BPA 0.61 7.41 0.55 1.72e-11 Neutrophil percentage of white cells; TGCT cis rs35306767 0.903 rs11253492 chr10:936873 T/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.57 -5.67 -0.45 9.59e-8 Electroencephalogram traits; TGCT cis rs7017914 0.905 rs3098879 chr8:71938460 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs2455799 0.613 rs2345736 chr3:15824860 T/G cg16303742 chr3:15540471 COLQ -0.24 -4.56 -0.38 1.21e-5 Mean platelet volume; TGCT cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg03806693 chr22:41940476 POLR3H -1.01 -10.3 -0.68 2.33e-18 Vitiligo; TGCT cis rs986417 0.901 rs4640083 chr14:61097779 G/A cg27398547 chr14:60952738 C14orf39 1.56 8.73 0.62 1.45e-14 Gut microbiota (bacterial taxa); TGCT cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3087591 1.000 rs2905870 chr17:29521833 G/A cg24425628 chr17:29625626 OMG;NF1 0.46 7.04 0.53 1.17e-10 Hip circumference; TGCT cis rs9913156 0.515 rs11658808 chr17:4577112 C/T cg19197139 chr17:4613644 ARRB2 -0.68 -6.7 -0.52 6.62e-10 Lymphocyte counts; TGCT cis rs7809950 0.834 rs2712199 chr7:107140239 A/G cg23024343 chr7:107201750 COG5 -0.36 -5.51 -0.44 1.97e-7 Coronary artery disease; TGCT cis rs6988636 1.000 rs58741168 chr8:124191852 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1577917 1.000 rs1337850 chr6:86729103 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs6835098 0.923 rs9997477 chr4:174112543 C/T cg08422745 chr4:174089978 GALNT7 -0.93 -10.96 -0.7 5.82e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7567389 0.704 rs4662714 chr2:127995213 A/G cg09760422 chr2:128146352 NA -0.35 -4.43 -0.37 2.01e-5 Self-rated health; TGCT cis rs7769051 1.000 rs58832890 chr6:133127139 C/T cg22852734 chr6:133119734 C6orf192 1.23 6.98 0.53 1.58e-10 Type 2 diabetes nephropathy; TGCT cis rs6598955 0.670 rs12733645 chr1:26540356 G/T cg01614726 chr1:26633154 UBXN11 0.49 4.69 0.39 7.09e-6 Obesity-related traits; TGCT cis rs9640161 0.789 rs1047207 chr7:150037660 A/G cg17279839 chr7:150038598 RARRES2 0.45 4.84 0.4 3.81e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs6071524 0.508 rs2247983 chr20:37397909 C/T cg09937324 chr20:37376998 ACTR5 -0.58 -4.56 -0.38 1.19e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.520 rs11123764 chr2:99750677 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs12477438 0.735 rs12474477 chr2:99690408 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.09 -0.48 1.32e-8 Chronic sinus infection; TGCT cis rs7611238 0.538 rs6806763 chr3:195109760 A/C cg27323046 chr3:195102265 ACAP2 0.37 4.93 0.4 2.56e-6 Body mass index; TGCT cis rs9517320 0.534 rs3858776 chr13:99161457 C/T cg07423050 chr13:99094983 FARP1 -0.29 -5.83 -0.46 4.43e-8 Longevity; TGCT cis rs4285028 0.747 rs9820511 chr3:121361345 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs4689592 0.503 rs2292461 chr4:7058473 C/T cg02503808 chr4:7069936 GRPEL1 0.88 7.48 0.56 1.2e-11 Monocyte percentage of white cells; TGCT cis rs6666258 0.924 rs12754189 chr1:154812630 T/C cg06418219 chr1:154948305 SHC1;CKS1B 0.65 5.22 0.42 7.23e-7 Atrial fibrillation; TGCT trans rs57221529 0.766 rs56216231 chr5:581193 G/A cg25482853 chr8:67687455 SGK3 1.17 11.24 0.71 1.19e-20 Lung disease severity in cystic fibrosis; TGCT cis rs9611519 0.808 rs5751074 chr22:41665722 G/A cg03806693 chr22:41940476 POLR3H -0.77 -7.46 -0.56 1.3e-11 Neuroticism; TGCT cis rs7085104 0.684 rs7092690 chr10:104609365 T/C cg04362960 chr10:104952993 NT5C2 0.58 5.14 0.42 1.04e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7824557 0.736 rs6601578 chr8:11136604 A/G cg21775007 chr8:11205619 TDH -0.59 -5.57 -0.45 1.54e-7 Retinal vascular caliber; TGCT cis rs9443645 0.868 rs9443643 chr6:79798838 A/G cg09184832 chr6:79620586 NA -0.48 -5.23 -0.43 6.99e-7 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT trans rs797680 0.856 rs535760 chr1:93728758 T/A cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7829975 0.626 rs332040 chr8:8730488 G/A cg06636001 chr8:8085503 FLJ10661 0.71 6.57 0.51 1.26e-9 Mood instability; TGCT cis rs8070128 0.637 rs4925133 chr17:17884801 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.5 0.56 1.05e-11 Total body bone mineral density; TGCT cis rs9788721 0.836 rs11858836 chr15:78783277 G/A cg18825076 chr15:78729989 IREB2 -0.35 -5.19 -0.42 8.3e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs4665809 0.887 rs4665825 chr2:26333100 A/G cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs3784262 0.679 rs11071366 chr15:58334244 A/T cg12031962 chr15:58353849 ALDH1A2 -0.55 -8.46 -0.6 6.31e-14 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs10088262 0.629 rs7833650 chr8:124822969 C/T cg20713898 chr8:124780851 FAM91A1 -0.89 -7.32 -0.55 2.8e-11 Pancreatic cancer; TGCT cis rs7959452 0.640 rs11177599 chr12:69721970 G/A cg14784868 chr12:69753453 YEATS4 0.67 6.93 0.53 2.07e-10 Blood protein levels; TGCT cis rs1018836 0.851 rs7014073 chr8:91618548 T/C cg16814680 chr8:91681699 NA -0.83 -8.65 -0.61 2.22e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9467711 0.606 rs9393711 chr6:26370659 C/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs79976124 0.837 rs10455591 chr6:66650584 A/G cg07460842 chr6:66804631 NA 0.58 5.29 0.43 5.33e-7 Type 2 diabetes; TGCT cis rs11230394 0.916 rs17627788 chr11:60384540 C/T cg24026212 chr11:59952134 MS4A6A 0.29 4.64 0.38 8.85e-6 Gestational age at birth in premature rupture of membrane-initiated deliveries (child effect); TGCT cis rs854765 0.583 rs67253360 chr17:17828973 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs35146811 0.735 rs1727139 chr7:99815367 C/T cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs6570726 0.791 rs401331 chr6:145831408 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs2469997 1.000 rs2470009 chr8:120359377 T/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs13256369 0.755 rs11776987 chr8:8559401 C/G cg17143192 chr8:8559678 CLDN23 0.53 4.82 0.4 4.03e-6 Obesity-related traits; TGCT cis rs68170813 0.559 rs17350182 chr7:106909637 T/A cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs9611519 1.000 rs9611519 chr22:41613188 C/T cg13695892 chr22:41940480 POLR3H -0.5 -4.5 -0.37 1.56e-5 Neuroticism; TGCT cis rs1475911 0.947 rs67055914 chr21:43510427 T/C cg14562523 chr21:43528734 C21orf128;UMODL1 -0.23 -4.69 -0.39 7.13e-6 IgG glycosylation; TGCT cis rs7659604 0.840 rs6821305 chr4:122713863 A/C cg19748678 chr4:122722346 EXOSC9 0.73 7.4 0.55 1.82e-11 Type 2 diabetes; TGCT cis rs1903068 0.962 rs17773813 chr4:56008969 G/A cg09978860 chr4:56023921 NA 0.58 6.61 0.51 1.02e-9 Endometriosis; TGCT cis rs2180341 0.920 rs9401951 chr6:127671632 A/C cg24812749 chr6:127587940 RNF146 1.02 7.59 0.56 6.71e-12 Breast cancer; TGCT cis rs240764 0.853 rs17303769 chr6:100967531 G/A cg21058520 chr6:100914733 NA 0.35 4.63 0.38 9.07e-6 Neuroticism; TGCT cis rs1976403 0.659 rs10799700 chr1:21820968 G/C cg17800788 chr1:21766015 NBPF3 0.24 4.51 0.38 1.46e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7582180 0.614 rs2241809 chr2:101014363 C/T cg08017756 chr2:100939284 LONRF2 -0.29 -4.67 -0.39 7.68e-6 Intelligence (multi-trait analysis); TGCT cis rs950776 0.518 rs11636131 chr15:78821606 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs7666738 0.830 rs10028692 chr4:98962585 C/T cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7681440 0.904 rs6816736 chr4:90765746 G/A cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT trans rs11088226 0.681 rs4547609 chr21:33953542 G/A cg09050820 chr6:167586206 TCP10L2 0.76 7.31 0.55 2.88e-11 Gastritis; TGCT cis rs7572733 0.534 rs6760891 chr2:198768166 T/G cg00792783 chr2:198669748 PLCL1 0.56 5.11 0.42 1.21e-6 Dermatomyositis; TGCT cis rs7833790 0.963 rs28823280 chr8:82777716 G/A cg17211192 chr8:82754475 SNX16 1.01 8.69 0.62 1.77e-14 Diastolic blood pressure; TGCT cis rs9807989 0.507 rs2110659 chr2:103043867 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs7681440 0.904 rs1822217 chr4:90765052 C/T cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs17376456 0.825 rs28534784 chr5:93063332 C/A cg25358565 chr5:93447407 FAM172A 0.9 7.98 0.58 8.23e-13 Diabetic retinopathy; TGCT cis rs6671200 0.607 rs3767315 chr1:95705972 A/G cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs2717559 0.522 rs2572925 chr8:143867905 C/T cg07661805 chr8:143867942 LY6D 0.23 4.47 0.37 1.77e-5 Urinary tract infection frequency; TGCT cis rs7226408 0.790 rs55935783 chr18:34346120 A/C cg06757138 chr18:34340585 FHOD3 0.29 4.97 0.41 2.14e-6 Obesity-related traits; TGCT cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs11711311 0.822 rs9850256 chr3:113408382 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.67 -5.9 -0.47 3.26e-8 IgG glycosylation; TGCT cis rs921968 0.541 rs17462853 chr2:219345637 T/G cg02176678 chr2:219576539 TTLL4 -0.48 -6.84 -0.52 3.21e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs8064299 0.967 rs878906 chr17:72769334 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.79 8.01 0.58 7.17e-13 Monocyte count; TGCT cis rs6912958 0.781 rs9444524 chr6:88311260 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.55 -5.04 -0.41 1.62e-6 Monocyte percentage of white cells; TGCT cis rs7027203 0.797 rs3996254 chr9:96591239 A/G cg13679303 chr9:96623674 NA -0.66 -10.78 -0.7 1.64e-19 DNA methylation (variation); TGCT cis rs2730245 0.550 rs2709860 chr7:158651156 A/T cg24397884 chr7:158709396 WDR60 0.39 5.24 0.43 6.56e-7 Height; TGCT cis rs4478858 0.735 rs4949384 chr1:31792141 A/G cg00250761 chr1:31883323 NA -0.27 -4.78 -0.39 4.86e-6 Alcohol dependence; TGCT cis rs4478858 0.746 rs12136121 chr1:31689743 G/C cg00250761 chr1:31883323 NA 0.29 4.88 0.4 3.25e-6 Alcohol dependence; TGCT cis rs7949030 0.626 rs72927213 chr11:62351198 G/C cg13298116 chr11:62369859 EML3;MTA2 0.63 9.39 0.64 3.71e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9926296 0.712 rs459920 chr16:89730827 T/C cg01097406 chr16:89675127 NA 0.34 5.88 0.47 3.54e-8 Vitiligo; TGCT cis rs11190604 0.767 rs10883481 chr10:102165021 G/A cg16005271 chr10:102321736 NA 0.45 4.57 0.38 1.15e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6433895 1.000 rs11893821 chr2:182017148 A/G cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT trans rs459571 1.000 rs459571 chr9:136912626 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.77 -8.3 -0.6 1.47e-13 Platelet distribution width; TGCT cis rs12681287 0.570 rs10956830 chr8:87430483 T/A cg27223183 chr8:87520930 FAM82B 0.89 6.43 0.5 2.54e-9 Caudate activity during reward; TGCT cis rs2816062 0.775 rs2816046 chr1:18893708 A/G cg18795169 chr1:18902165 NA -0.59 -13.32 -0.77 1.12e-25 Urate levels in lean individuals; TGCT cis rs909674 0.818 rs5750833 chr22:39843091 C/A cg02038168 chr22:39784481 NA -0.71 -5.56 -0.45 1.54e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg06618935 chr21:46677482 NA -0.37 -5.68 -0.45 9.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7017914 0.967 rs1493198 chr8:71851957 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.07 -0.41 1.39e-6 Bone mineral density; TGCT cis rs79724016 1.000 rs1105414 chr1:42144764 C/T cg07578001 chr1:42501544 NA -0.99 -4.45 -0.37 1.91e-5 Breast cancer; TGCT cis rs9486719 0.843 rs2499789 chr6:96844510 T/C cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg00814883 chr7:100076585 TSC22D4 -0.82 -8.23 -0.59 2.14e-13 Platelet count; TGCT cis rs4665809 1.000 rs12469163 chr2:26283587 T/C cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs1008375 0.932 rs6814465 chr4:17659034 C/T cg16339924 chr4:17578868 LAP3 0.66 5.52 0.44 1.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7727544 0.684 rs611084 chr5:131709739 A/C cg24060327 chr5:131705240 SLC22A5 0.62 6.77 0.52 4.69e-10 Blood metabolite levels; TGCT cis rs2742417 1.000 rs2673058 chr3:45735618 A/C cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2777491 0.915 rs16971767 chr15:41623308 T/C cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.44 -0.68 1.07e-18 Ulcerative colitis; TGCT cis rs8031584 0.678 rs798125 chr15:31116800 C/T cg08704250 chr15:31115839 NA 0.44 6.43 0.5 2.47e-9 Huntington's disease progression; TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg11965913 chr1:205819406 PM20D1 0.53 7.4 0.55 1.82e-11 Menarche (age at onset); TGCT trans rs208520 0.837 rs208509 chr6:66941706 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.85 -0.66 3e-17 Exhaled nitric oxide output; TGCT cis rs796364 0.906 rs281766 chr2:200820505 T/G cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs2288884 1.000 rs76768215 chr19:52572623 C/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg11965913 chr1:205819406 PM20D1 -0.47 -6.5 -0.5 1.8e-9 Monocyte percentage of white cells; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg01802117 chr1:53393560 SCP2 -0.42 -4.85 -0.4 3.63e-6 Monocyte count; TGCT cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg05368731 chr17:41323189 NBR1 1.1 11.12 0.71 2.38e-20 Menopause (age at onset); TGCT cis rs736408 0.648 rs3774354 chr3:52817675 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.53 0.51 1.55e-9 Bipolar disorder; TGCT cis rs9611565 0.572 rs139569 chr22:42211141 A/G cg03806693 chr22:41940476 POLR3H -0.88 -8.45 -0.6 6.8e-14 Vitiligo; TGCT cis rs35146811 0.624 rs1727134 chr7:99813672 T/C cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs6540559 0.611 rs6540563 chr1:210019858 C/G cg23283495 chr1:209979779 IRF6 0.6 4.5 0.37 1.54e-5 Cleft lip with or without cleft palate; TGCT trans rs1814175 0.645 rs1851845 chr11:49982396 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs76878669 0.561 rs12416747 chr11:66135614 A/G cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.89e-9 Educational attainment (years of education); TGCT cis rs12681288 0.748 rs7000148 chr8:1016383 G/C cg04851639 chr8:1020857 NA -0.37 -6.84 -0.52 3.24e-10 Schizophrenia; TGCT cis rs939658 0.805 rs11634679 chr15:79432475 T/C cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs8179 1.000 rs42033 chr7:92237533 A/T cg15732164 chr7:92237376 CDK6 -0.33 -4.9 -0.4 2.99e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs1532993 0.518 rs12512518 chr4:98633283 G/C cg05340658 chr4:99064831 C4orf37 -0.4 -4.91 -0.4 2.77e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs8056742 0.643 rs12926648 chr16:85092970 T/C cg00229868 chr16:85520891 NA 0.34 4.8 0.4 4.39e-6 Amyotrophic lateral sclerosis; TGCT cis rs10510102 0.745 rs7076882 chr10:123706554 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs4455778 0.580 rs4917197 chr7:49075894 C/T cg26309511 chr7:48887640 NA 0.5 6.36 0.5 3.57e-9 Lung cancer in never smokers; TGCT cis rs1348850 0.632 rs12471621 chr2:178502353 T/C cg22681709 chr2:178499509 PDE11A -0.53 -6.64 -0.51 8.93e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs12908161 1.000 rs35524990 chr15:85258203 T/C cg11189052 chr15:85197271 WDR73 0.75 6.29 0.49 5.02e-9 Schizophrenia; TGCT cis rs1008375 0.931 rs10939733 chr4:17570658 T/C cg16339924 chr4:17578868 LAP3 0.82 7.13 0.54 7.32e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9296092 0.538 rs112113649 chr6:33524529 A/G cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs76878669 0.561 rs7948058 chr11:66148111 T/A cg18002602 chr11:66138449 SLC29A2 -0.54 -6.59 -0.51 1.15e-9 Educational attainment (years of education); TGCT cis rs981844 0.816 rs56413502 chr4:154721784 T/A cg14289246 chr4:154710475 SFRP2 1.03 9.03 0.63 2.72e-15 Response to statins (LDL cholesterol change); TGCT cis rs61990749 0.597 rs17106157 chr14:78146878 C/T cg02301378 chr14:78227641 SNW1;C14orf178 -0.63 -4.62 -0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs4689388 0.926 rs4688987 chr4:6287329 C/T cg14416269 chr4:6271139 WFS1 0.39 5.22 0.42 7.41e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4509693 0.943 rs4917907 chr10:102498140 A/G cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs4704846 1.000 rs4704851 chr5:156533174 C/T cg12943317 chr5:156479607 HAVCR1 -0.34 -4.7 -0.39 6.82e-6 Blood protein levels; TGCT cis rs670523 0.532 rs6427297 chr1:155975493 C/T cg13795986 chr1:155880507 RIT1 0.37 4.61 0.38 9.72e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs78707713 0.560 rs61848398 chr10:71226103 G/A cg12610070 chr10:71211762 TSPAN15 -0.62 -7.37 -0.55 2.14e-11 Venous thromboembolism; TGCT cis rs10883723 0.810 rs7090034 chr10:104281155 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4319547 0.626 rs11057882 chr12:122875046 A/G cg05707623 chr12:122985044 ZCCHC8 -0.62 -4.87 -0.4 3.32e-6 Body mass index; TGCT cis rs2721195 0.816 rs4925826 chr8:145706276 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 0.88 9.59 0.65 1.22e-16 Age at first birth; TGCT cis rs9583531 0.891 rs9521911 chr13:111370615 A/G cg24331049 chr13:111365604 ING1 -0.74 -5.05 -0.41 1.54e-6 Coronary artery disease; TGCT cis rs4851266 1.000 rs1160543 chr2:100832182 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs12971120 0.891 rs11151960 chr18:72177232 G/A cg26446133 chr18:72167187 CNDP2 -0.35 -5.89 -0.47 3.42e-8 Refractive error; TGCT cis rs6450176 0.909 rs80213371 chr5:53300874 T/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs4653663 0.785 rs4653662 chr1:225921655 A/G cg06802365 chr1:225117676 DNAH14 -0.51 -4.46 -0.37 1.82e-5 Neuroticism; TGCT cis rs9916302 0.851 rs12936996 chr17:37665554 A/G cg07936489 chr17:37558343 FBXL20 0.61 4.81 0.4 4.25e-6 Glomerular filtration rate (creatinine); TGCT cis rs4819052 1.000 rs3746980 chr21:46711580 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.76 5.6 0.45 1.28e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9916302 0.706 rs649180 chr17:37464959 A/C cg03321784 chr17:37729644 NA -0.43 -4.46 -0.37 1.84e-5 Glomerular filtration rate (creatinine); TGCT cis rs7772486 0.743 rs111332144 chr6:146056681 C/T cg23711669 chr6:146136114 FBXO30 -0.77 -7.33 -0.55 2.65e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs11864453 0.826 rs12448315 chr16:72147242 G/T cg14768367 chr16:72042858 DHODH 0.48 4.47 0.37 1.77e-5 Fibrinogen levels; TGCT cis rs4662750 0.674 rs777437 chr2:128357647 C/T cg20053821 chr2:127529534 NA 0.23 4.47 0.37 1.74e-5 Renal cell carcinoma; TGCT cis rs7647973 0.626 rs9835157 chr3:49797769 G/A cg05785598 chr3:49045655 WDR6 -0.42 -5.24 -0.43 6.67e-7 Menarche (age at onset); TGCT cis rs9534288 0.797 rs7982998 chr13:46601535 C/T cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs6121246 0.779 rs6060763 chr20:30282223 A/G cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs2153535 0.580 rs7742689 chr6:8452433 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs1348850 0.567 rs4893838 chr2:178531436 T/C cg22681709 chr2:178499509 PDE11A -0.46 -5.95 -0.47 2.58e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1218582 0.600 rs72702224 chr1:154911689 G/A cg09359103 chr1:154839909 KCNN3 -0.65 -12.35 -0.74 2.43e-23 Prostate cancer; TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg21672276 chr3:44754072 ZNF502 -0.55 -6.31 -0.49 4.58e-9 Depressive symptoms; TGCT cis rs288326 0.561 rs78745965 chr2:183848475 T/C cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs2455799 0.613 rs2470542 chr3:15724133 A/C cg16303742 chr3:15540471 COLQ -0.24 -4.52 -0.38 1.4e-5 Mean platelet volume; TGCT cis rs7568458 0.870 rs2366639 chr2:85809955 A/G cg17127132 chr2:85788382 GGCX 0.68 6.2 0.49 7.54e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7226408 0.857 rs72885294 chr18:34450941 T/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6867032 0.917 rs10474734 chr5:2004208 A/G cg26168224 chr5:2018326 NA 0.33 5.04 0.41 1.64e-6 Gut microbiome composition (winter); TGCT cis rs2153535 0.601 rs9328487 chr6:8529378 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs939658 1.000 rs8027411 chr15:79461029 G/T cg17916960 chr15:79447300 NA 0.52 8.38 0.6 9.77e-14 Refractive error; TGCT cis rs11785400 0.793 rs4736366 chr8:143742413 C/T cg24634471 chr8:143751801 JRK 0.55 5.45 0.44 2.6e-7 Schizophrenia; TGCT cis rs7772486 0.875 rs863820 chr6:146347402 C/T cg05347473 chr6:146136440 FBXO30 -0.57 -5.51 -0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4595586 0.545 rs12819061 chr12:39386976 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs9993613 0.875 rs6812147 chr4:73475839 T/G cg15102770 chr4:73434591 ADAMTS3 0.54 4.96 0.41 2.26e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs4901869 0.902 rs10149194 chr14:59308198 A/G cg02291164 chr14:59296302 NA -0.25 -4.69 -0.39 7.15e-6 Panic disorder; TGCT cis rs3820928 0.874 rs10183633 chr2:227887828 A/G cg11843606 chr2:227700838 RHBDD1 -0.57 -5.23 -0.42 7.12e-7 Pulmonary function; TGCT cis rs709400 0.659 rs7160366 chr14:103944137 C/T cg12935359 chr14:103987150 CKB -0.36 -5.55 -0.45 1.67e-7 Body mass index; TGCT cis rs6951245 0.529 rs10262070 chr7:1141738 C/T cg03188948 chr7:1209495 NA 0.48 5.12 0.42 1.11e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg11644478 chr21:40555479 PSMG1 -0.62 -5.88 -0.47 3.5e-8 Cognitive function; TGCT cis rs7208859 0.623 rs7220999 chr17:29149298 C/T cg13385521 chr17:29058706 SUZ12P 0.81 4.85 0.4 3.68e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs735396 0.770 rs2264782 chr12:121432603 C/T cg02403541 chr12:121454288 C12orf43 0.64 5.88 0.47 3.6e-8 N-glycan levels; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg15242686 chr22:24348715 GSTTP1 -0.5 -7.57 -0.56 7.42e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7647973 0.710 rs6797299 chr3:49609794 G/T cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs2239547 0.522 rs4519686 chr3:52997871 C/T cg10802521 chr3:52805072 NEK4 -0.63 -6.05 -0.48 1.59e-8 Schizophrenia; TGCT trans rs1005277 0.541 rs2505193 chr10:38394638 G/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs4819052 0.851 rs2255766 chr21:46683777 C/T cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9972944 0.756 rs7221131 chr17:63764848 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs10751667 0.666 rs6597958 chr11:978087 C/T cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs5769707 0.681 rs4622843 chr22:50036916 T/G cg06623630 chr22:50017776 C22orf34 -0.26 -4.52 -0.38 1.42e-5 Monocyte count;Monocyte percentage of white cells; TGCT trans rs7819412 0.805 rs2409710 chr8:10979821 A/G cg15556689 chr8:8085844 FLJ10661 -0.82 -8.29 -0.6 1.61e-13 Triglycerides; TGCT cis rs10984561 0.881 rs73540255 chr9:122255508 T/C cg14242995 chr9:122249943 NA 0.72 5.82 0.46 4.75e-8 Pulmonary function decline; TGCT cis rs6728642 0.908 rs10207116 chr2:98018281 G/A cg26665480 chr2:98280029 ACTR1B -0.95 -5.3 -0.43 5.14e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs7216169 1 rs7216169 chr17:5219511 C/T cg02842197 chr17:5389625 DERL2;MIS12 0.8 4.56 0.38 1.21e-5 Red blood cell density in sickle cell anemia; TGCT cis rs4665809 1.000 rs6546728 chr2:26276531 G/C cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs12477438 0.501 rs34272114 chr2:99737443 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs2854160 0.581 rs2727319 chr17:61960215 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.5 0.44 2.06e-7 Height; TGCT cis rs6951245 0.554 rs78999139 chr7:1138525 G/A cg18402987 chr7:1209562 NA 0.48 4.79 0.39 4.72e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7611238 0.560 rs9879305 chr3:195074094 T/C cg27323046 chr3:195102265 ACAP2 0.35 4.82 0.4 4.11e-6 Body mass index; TGCT cis rs6674176 0.597 rs4031031 chr1:44393533 C/T cg13606994 chr1:44402422 ARTN -0.52 -5.47 -0.44 2.33e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs853679 0.517 rs4713146 chr6:28111536 A/T cg12963246 chr6:28129442 ZNF389 0.52 5.04 0.41 1.61e-6 Depression; TGCT cis rs78707713 0.560 rs2394563 chr10:71238618 G/A cg14388049 chr10:71211838 TSPAN15 -0.39 -4.64 -0.38 8.84e-6 Venous thromboembolism; TGCT cis rs7267979 1.000 rs3761117 chr20:25388070 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7617773 0.780 rs6782166 chr3:48351683 A/G cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs7267979 0.932 rs6115215 chr20:25562500 C/T cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1552244 0.572 rs59074548 chr3:10164347 G/C cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs7666738 0.830 rs11935588 chr4:98979862 A/G cg05340658 chr4:99064831 C4orf37 -0.53 -6.01 -0.47 1.93e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.54 -0.51 1.42e-9 Alzheimer's disease; TGCT cis rs7547997 0.649 rs7543890 chr1:158342937 A/G cg07950803 chr1:158223934 CD1A 0.32 4.78 0.39 4.95e-6 QRS duration; TGCT cis rs7772486 0.805 rs4896831 chr6:145959481 T/C cg23711669 chr6:146136114 FBXO30 0.79 8.38 0.6 9.86e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs11578119 0.872 rs17350312 chr1:170377400 T/C cg09767346 chr1:170501363 GORAB 0.74 5.92 0.47 2.94e-8 Male-pattern baldness; TGCT cis rs7100689 0.622 rs1340383 chr10:82095968 T/G cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs7666738 0.830 rs7678250 chr4:98922109 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9527 0.590 rs3861984 chr10:104916980 T/C cg15744005 chr10:104629667 AS3MT -0.41 -4.73 -0.39 6.06e-6 Arsenic metabolism; TGCT cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT trans rs7618501 0.699 rs2681780 chr3:49897830 C/T cg21659725 chr3:3221576 CRBN 0.79 9.28 0.64 6.9e-16 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.851 rs6089827 chr20:61668845 C/T cg18188782 chr20:61659543 NA 0.47 5.63 0.45 1.15e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs67311347 1.000 rs6795475 chr3:40489281 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.73 0.39 5.9e-6 Renal cell carcinoma; TGCT cis rs7829975 0.593 rs2921051 chr8:8320104 C/A cg08975724 chr8:8085496 FLJ10661 0.62 6.02 0.48 1.87e-8 Mood instability; TGCT cis rs9393777 0.844 rs35909544 chr6:27163456 G/A cg16898833 chr6:26189333 HIST1H4D 0.87 4.89 0.4 3.06e-6 Intelligence (multi-trait analysis); TGCT cis rs7100689 0.646 rs7077854 chr10:82124070 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs427394 0.582 rs274665 chr5:6707981 C/T cg10857441 chr5:6722123 POLS -0.3 -6.4 -0.5 2.95e-9 Menopause (age at onset); TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg11494091 chr17:61959527 GH2 0.61 14.78 0.8 4.02e-29 Prudent dietary pattern; TGCT cis rs6500602 0.826 rs11076831 chr16:4460133 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.44 -5.71 -0.46 7.83e-8 Schizophrenia; TGCT cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs8013055 0.796 rs28733392 chr14:105993258 G/A cg23356831 chr14:105996513 TMEM121 0.35 5.1 0.42 1.22e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs4812048 0.793 rs7266693 chr20:57593158 T/C cg24457521 chr20:57607420 ATP5E -0.69 -4.56 -0.38 1.22e-5 Mean platelet volume; TGCT cis rs7726839 0.540 rs72705097 chr5:655067 G/A cg16624210 chr5:671434 TPPP 0.41 4.6 0.38 1.02e-5 Obesity-related traits; TGCT cis rs72781680 0.716 rs2712050 chr2:24059408 A/C cg08917208 chr2:24149416 ATAD2B 0.77 4.8 0.4 4.46e-6 Lymphocyte counts; TGCT cis rs7119038 0.629 rs11216994 chr11:118603520 C/T cg19308663 chr11:118741387 NA 0.23 4.49 0.37 1.62e-5 Sjögren's syndrome; TGCT cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg22166914 chr1:53195759 ZYG11B -0.47 -8.62 -0.61 2.66e-14 Monocyte count; TGCT cis rs611744 0.901 rs673981 chr8:109191917 G/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs9611565 0.512 rs5751153 chr22:42156561 T/C cg06481639 chr22:41940642 POLR3H 0.69 6.02 0.48 1.83e-8 Vitiligo; TGCT cis rs832540 0.695 rs702686 chr5:56201350 A/G cg24531977 chr5:56204891 C5orf35 -0.66 -6.67 -0.51 7.66e-10 Coronary artery disease; TGCT cis rs2075371 1.000 rs1421484 chr7:133979795 T/C cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.64 0.38 8.8e-6 Renal cell carcinoma; TGCT cis rs10782582 0.545 rs12138018 chr1:76186794 T/C cg10523679 chr1:76189770 ACADM -0.67 -6.62 -0.51 9.61e-10 Daytime sleep phenotypes; TGCT cis rs4654899 0.895 rs10916866 chr1:21137768 C/A cg01072550 chr1:21505969 NA 0.55 8.83 0.62 8.24e-15 Superior frontal gyrus grey matter volume; TGCT cis rs12693043 0.817 rs10930673 chr2:175375315 G/A cg11778734 chr2:175439522 WIPF1 -0.35 -4.48 -0.37 1.68e-5 Urate levels (BMI interaction); TGCT cis rs17076896 0.786 rs74038129 chr13:19932807 A/T cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.57 -5.67 -0.45 9.34e-8 Electroencephalogram traits; TGCT cis rs11577318 0.853 rs3795684 chr1:26632781 C/T cg12733254 chr1:26682999 NA -0.2 -4.49 -0.37 1.62e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs9527 0.567 rs6584539 chr10:104879402 G/C cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs7267979 0.738 rs2892409 chr20:25638138 C/T cg16686733 chr20:25566563 NINL 0.48 4.62 0.38 9.4e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12776158 0.901 rs12413873 chr10:71212091 C/G cg12610070 chr10:71211762 TSPAN15 -0.56 -4.73 -0.39 6.07e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs6693567 0.586 rs9661040 chr1:150483236 A/C cg07843065 chr1:150265600 MRPS21 -0.17 -4.47 -0.37 1.72e-5 Migraine; TGCT trans rs7618501 0.633 rs2008877 chr3:50162291 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.75 -0.66 5.11e-17 Intelligence (multi-trait analysis); TGCT cis rs155076 1.000 rs564685 chr13:21846879 A/G cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs12142240 0.698 rs72677600 chr1:46834449 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.87 -0.4 3.31e-6 Menopause (age at onset); TGCT cis rs6952808 1.000 rs4256490 chr7:1890764 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.63 -0.45 1.13e-7 Bipolar disorder and schizophrenia; TGCT cis rs7729723 0.568 rs6885225 chr5:137824837 T/C cg19169342 chr5:137827400 NA 0.32 4.47 0.37 1.74e-5 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT trans rs1005277 0.579 rs1780138 chr10:38501654 A/G cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs12368653 0.557 rs903067 chr12:58011857 G/A cg00700412 chr12:58011837 NA -0.24 -4.73 -0.39 5.97e-6 Multiple sclerosis; TGCT cis rs1801251 0.778 rs2250654 chr2:233752376 A/T cg25237894 chr2:233734115 C2orf82 -0.31 -5.84 -0.46 4.25e-8 Coronary artery disease; TGCT cis rs4478858 0.735 rs12563669 chr1:31858067 A/G cg07478791 chr1:31886160 SERINC2 -0.52 -5.29 -0.43 5.27e-7 Alcohol dependence; TGCT cis rs9457247 0.555 rs2247325 chr6:167369992 A/G cg23791538 chr6:167370224 RNASET2 0.64 6.0 0.47 2.04e-8 Crohn's disease; TGCT cis rs6089584 0.888 rs6587283 chr20:60613727 A/C cg13665807 chr20:60559372 TAF4 -0.46 -4.94 -0.41 2.48e-6 Body mass index; TGCT cis rs10883723 0.810 rs7072351 chr10:104265047 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs72720396 0.803 rs114328297 chr1:91190854 T/G cg13456504 chr1:91191583 NA 0.74 5.83 0.46 4.57e-8 Morning vs. evening chronotype;Chronotype; TGCT cis rs585510 1 rs585510 chr12:121000133 A/G cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 Reticulocyte fraction of red cells; TGCT cis rs933688 0.938 rs1477348 chr5:90707823 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 8.03 0.58 6.35e-13 Smoking behavior; TGCT cis rs7208859 0.614 rs216412 chr17:28903394 A/G cg04154034 chr17:28927549 LRRC37B2 -0.87 -5.53 -0.44 1.81e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6087990 0.835 rs4911106 chr20:31331330 A/G cg13636640 chr20:31349939 DNMT3B 1.03 14.85 0.8 2.67e-29 Ulcerative colitis; TGCT cis rs4665809 0.818 rs35413760 chr2:26267137 C/A cg25036284 chr2:26402008 FAM59B 0.57 4.49 0.37 1.59e-5 Gut microbiome composition (summer); TGCT cis rs35883536 0.647 rs10875312 chr1:101042320 G/C cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.1e-12 Monocyte count; TGCT cis rs7312933 0.584 rs6582391 chr12:42634686 G/A cg19980929 chr12:42632907 YAF2 0.41 5.86 0.47 3.85e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT trans rs66573146 0.634 rs55633489 chr4:6988745 C/A cg07817883 chr1:32538562 TMEM39B 1.3 6.83 0.52 3.41e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs35306767 0.715 rs17221463 chr10:1038040 T/C cg20503657 chr10:835505 NA 0.63 6.98 0.53 1.57e-10 Eosinophil percentage of granulocytes; TGCT cis rs10504229 0.871 rs10504226 chr8:58159283 A/G cg22535103 chr8:58192502 C8orf71 -0.39 -4.73 -0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs6681544 0.760 rs2026597 chr1:82425956 T/A cg04226724 chr1:82268649 LPHN2 -0.48 -4.95 -0.41 2.42e-6 Metabolite levels (X-11787); TGCT cis rs2996428 0.667 rs61768933 chr1:3766587 G/A cg17848003 chr1:3704513 LRRC47 0.18 5.15 0.42 9.99e-7 Red cell distribution width; TGCT cis rs9325144 0.600 rs1817648 chr12:38733424 C/T cg13010199 chr12:38710504 ALG10B -0.51 -4.47 -0.37 1.76e-5 Morning vs. evening chronotype; TGCT cis rs2594989 1.000 rs346077 chr3:11326102 A/C cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs651907 0.535 rs34161138 chr3:101510388 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs2637266 1.000 rs2130798 chr10:78329563 C/T cg18941641 chr10:78392320 NA 0.41 4.97 0.41 2.17e-6 Pulmonary function; TGCT cis rs7714584 1.000 rs7732643 chr5:150261436 A/T cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs13242816 1.000 rs13242816 chr7:116189376 C/T cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs40363 0.620 rs1137454 chr16:3533577 C/G cg21433313 chr16:3507492 NAT15 -0.35 -4.53 -0.38 1.36e-5 Tuberculosis; TGCT cis rs7582180 0.614 rs4851309 chr2:100975390 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.38e-6 Intelligence (multi-trait analysis); TGCT cis rs10779751 1.000 rs2253213 chr1:11265785 A/G cg08854313 chr1:11322531 MTOR 1.0 9.07 0.63 2.26e-15 Body mass index; TGCT cis rs6964587 1.000 rs13245393 chr7:91641928 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs3806843 0.868 rs2531352 chr5:140119534 A/G cg19875535 chr5:140030758 IK -0.35 -5.94 -0.47 2.67e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2019216 0.500 rs7359613 chr17:21944028 T/C cg22648282 chr17:21454238 C17orf51 -0.58 -4.95 -0.41 2.37e-6 Pelvic organ prolapse; TGCT cis rs4765905 0.610 rs2238053 chr12:2317096 C/T cg07807026 chr12:2041581 NA 0.24 4.51 0.38 1.47e-5 Schizophrenia; TGCT cis rs6570726 0.935 rs409121 chr6:145839793 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs11785400 1.000 rs7459630 chr8:143738585 A/C cg24634471 chr8:143751801 JRK 0.57 6.18 0.49 8.56e-9 Schizophrenia; TGCT cis rs10782582 0.609 rs1630587 chr1:76399787 T/C cg10523679 chr1:76189770 ACADM -0.58 -5.21 -0.42 7.7e-7 Daytime sleep phenotypes; TGCT cis rs2404602 0.716 rs67920045 chr15:76800084 G/A cg22467129 chr15:76604101 ETFA -0.48 -5.7 -0.46 8.38e-8 Blood metabolite levels; TGCT cis rs4273100 1.000 rs4924986 chr17:19242467 C/T cg01534423 chr17:18965556 NA -0.9 -6.22 -0.49 7.01e-9 Schizophrenia; TGCT cis rs10256972 0.616 rs6463001 chr7:1108272 A/C cg03188948 chr7:1209495 NA 0.43 5.33 0.43 4.54e-7 Longevity;Endometriosis; TGCT cis rs3772130 0.962 rs6768621 chr3:121530274 C/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg10295955 chr4:187884368 NA 0.96 14.31 0.79 5.09e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg05590025 chr7:65112418 INTS4L2 -0.76 -4.56 -0.38 1.21e-5 Diabetic kidney disease; TGCT cis rs10089 1.000 rs7713877 chr5:127428825 G/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.7e-13 Ileal carcinoids; TGCT cis rs11043280 0.703 rs11043275 chr12:122402723 T/C cg22168489 chr12:122356033 WDR66 0.21 4.63 0.38 9.2e-6 Mean platelet volume; TGCT cis rs34526934 0.608 rs13017511 chr2:177035395 A/G cg26754761 chr2:177040938 NA -0.29 -5.43 -0.44 2.86e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs4253772 0.550 rs6007830 chr22:46711323 C/T cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs7044106 0.791 rs4837793 chr9:123483621 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 7.01 0.53 1.37e-10 Hip circumference adjusted for BMI; TGCT cis rs4478858 0.735 rs68008576 chr1:31805905 T/C cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg11301795 chr4:187892539 NA -0.35 -5.41 -0.44 3.11e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs734999 0.588 rs745368 chr1:2524205 C/T cg18854424 chr1:2615690 NA 0.46 5.23 0.43 6.92e-7 Ulcerative colitis; TGCT cis rs826838 1.000 rs10880785 chr12:38655405 T/G cg13010199 chr12:38710504 ALG10B 0.77 6.31 0.49 4.59e-9 Heart rate; TGCT cis rs13191362 0.688 rs73035006 chr6:162997083 G/T cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9527 0.590 rs3740386 chr10:104931051 C/T cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.07e-7 Arsenic metabolism; TGCT cis rs16854884 0.770 rs1530477 chr3:143819506 A/G cg06585982 chr3:143692056 C3orf58 -0.59 -4.64 -0.38 8.56e-6 Economic and political preferences (feminism/equality); TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs4566357 1.000 rs10933167 chr2:227925969 T/C cg11843606 chr2:227700838 RHBDD1 -0.5 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs11696501 0.688 rs6094192 chr20:44297796 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs7267979 1.000 rs4815405 chr20:25317492 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 0.966 rs2500417 chr20:25383287 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7726839 0.540 rs72703078 chr5:594987 A/C cg25482853 chr8:67687455 SGK3 1.26 10.61 0.69 4.22e-19 Obesity-related traits; TGCT cis rs6570726 0.935 rs388394 chr6:145852689 C/T cg05347473 chr6:146136440 FBXO30 0.48 4.5 0.37 1.55e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs12579753 1.000 rs11115030 chr12:82203021 A/T cg07988820 chr12:82153109 PPFIA2 -0.65 -6.87 -0.52 2.82e-10 Resting heart rate; TGCT trans rs73411413 0.608 rs7126170 chr11:1539387 C/A cg13381631 chr10:46776799 NA -0.38 -6.68 -0.51 7.16e-10 Myringotomy; TGCT cis rs2072499 0.966 rs2244144 chr1:156184598 G/A cg24450063 chr1:156163899 SLC25A44 1.18 13.56 0.77 2.93e-26 Testicular germ cell tumor; TGCT cis rs5769707 0.681 rs2319346 chr22:50029640 A/G cg06623630 chr22:50017776 C22orf34 -0.27 -4.6 -0.38 1.04e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6089584 0.888 rs6142927 chr20:60605848 A/G cg06108461 chr20:60628389 TAF4 -0.64 -9.17 -0.64 1.27e-15 Body mass index; TGCT cis rs9650657 0.707 rs2005309 chr8:10652170 T/C cg27411982 chr8:10470053 RP1L1 -0.23 -4.99 -0.41 2.03e-6 Neuroticism; TGCT cis rs6459788 0.685 rs13226469 chr7:157235777 G/A cg06271696 chr7:157225062 NA -0.31 -5.45 -0.44 2.56e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs2721195 0.845 rs1063739 chr8:145729727 C/A cg11211951 chr8:145729740 GPT 0.28 6.65 0.51 8.38e-10 Age at first birth; TGCT cis rs79349575 0.783 rs4793995 chr17:47019399 A/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs910316 1.000 rs7156105 chr14:75541954 C/A cg11812906 chr14:75593930 NEK9 0.74 7.31 0.55 2.88e-11 Height; TGCT cis rs12791968 1.000 rs10838397 chr11:45009133 A/G cg11846598 chr11:44996168 LOC221122 0.31 5.97 0.47 2.33e-8 Inhibitory control; TGCT cis rs2404602 0.716 rs12917430 chr15:76674360 T/C cg22467129 chr15:76604101 ETFA -0.57 -6.7 -0.52 6.39e-10 Blood metabolite levels; TGCT cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.72 -6.26 -0.49 5.89e-9 Mean platelet volume; TGCT cis rs9911578 0.935 rs420878 chr17:56709077 A/G cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.607 rs7965392 chr12:42540280 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.56 5.14 0.42 1.03e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg00684032 chr4:1343700 KIAA1530 -0.22 -4.72 -0.39 6.18e-6 Obesity-related traits; TGCT cis rs2230307 0.536 rs11166409 chr1:100641411 T/C cg24955406 chr1:100503596 HIAT1 -0.73 -4.94 -0.41 2.5e-6 Carotid intima media thickness; TGCT cis rs4819052 1.000 rs3746980 chr21:46711580 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 1.0 8.27 0.6 1.74e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs597539 0.652 rs557625 chr11:68634722 G/A cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs8074700 0.539 rs3096649 chr17:46751157 A/T cg24803719 chr17:45855879 NA 0.39 4.5 0.38 1.51e-5 Body mass index in non-asthmatics; TGCT cis rs6933660 0.745 rs3800272 chr6:151744283 A/G cg14416726 chr6:151773293 C6orf211;RMND1 0.83 8.97 0.63 3.86e-15 Menarche (age at onset); TGCT cis rs734999 0.549 rs2764845 chr1:2528999 G/T cg18854424 chr1:2615690 NA -0.5 -5.78 -0.46 5.64e-8 Ulcerative colitis; TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg09060608 chr5:178986726 RUFY1 -0.62 -7.68 -0.57 4.22e-12 Lung cancer; TGCT cis rs73001065 0.901 rs73004967 chr19:19717056 A/G cg03709012 chr19:19516395 GATAD2A 1.19 5.43 0.44 2.88e-7 LDL cholesterol; TGCT cis rs9372498 0.536 rs62422229 chr6:118959288 T/C cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs4073582 0.595 rs801736 chr11:65928430 A/T cg16950941 chr11:66035639 RAB1B 0.55 5.42 0.44 2.94e-7 Gout; TGCT cis rs17384381 1.000 rs12140457 chr1:85860170 G/A cg16011679 chr1:85725395 C1orf52 0.8 6.44 0.5 2.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs8180040 0.966 rs12636851 chr3:47463567 C/T cg27129171 chr3:47204927 SETD2 0.64 7.39 0.55 1.89e-11 Colorectal cancer; TGCT cis rs11190604 1.000 rs11190552 chr10:102206607 G/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7924176 0.564 rs34868542 chr10:75986157 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.46 -4.52 -0.38 1.44e-5 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs270601 0.710 rs371709 chr5:131583240 A/G cg24060327 chr5:131705240 SLC22A5 -0.61 -6.32 -0.49 4.29e-9 Acylcarnitine levels; TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg08736216 chr1:53307985 ZYG11A -0.23 -4.56 -0.38 1.19e-5 Monocyte count; TGCT cis rs7937612 1.000 rs11601535 chr11:120333801 A/G cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.48 -0.37 1.66e-5 Intraocular pressure; TGCT cis rs911186 0.891 rs6914824 chr6:27139048 C/T cg16898833 chr6:26189333 HIST1H4D 0.74 4.48 0.37 1.71e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6087990 0.568 rs853854 chr20:31420757 T/A cg13636640 chr20:31349939 DNMT3B 0.85 9.01 0.63 3.16e-15 Ulcerative colitis; TGCT cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg03517284 chr6:25882590 NA -0.58 -5.3 -0.43 5.05e-7 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.933 rs2424708 chr20:25281398 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6586163 0.872 rs1926200 chr10:90746533 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.38 -4.78 -0.39 4.79e-6 Chronic lymphocytic leukemia; TGCT cis rs12497850 0.931 rs7628719 chr3:48995487 C/T cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.98e-6 Parkinson's disease; TGCT cis rs933688 1.000 rs12188467 chr5:90765632 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.48 0.69 8.43e-19 Smoking behavior; TGCT cis rs5769765 1.000 rs2295408 chr22:50261051 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.09 11.03 0.7 4e-20 Schizophrenia; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg08859206 chr1:53392774 SCP2 -0.45 -6.66 -0.51 7.99e-10 Monocyte count; TGCT cis rs2239547 0.657 rs6445538 chr3:52874288 T/C cg10802521 chr3:52805072 NEK4 -0.65 -6.12 -0.48 1.16e-8 Schizophrenia; TGCT cis rs2070488 0.662 rs7372545 chr3:38507570 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.65 5.11 0.42 1.19e-6 Electrocardiographic conduction measures; TGCT cis rs6964587 1.000 rs1063243 chr7:91726927 A/C cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs939658 0.935 rs2204069 chr15:79449335 A/G cg17916960 chr15:79447300 NA 0.55 8.82 0.62 8.87e-15 Refractive error; TGCT cis rs6570726 0.935 rs416987 chr6:145847005 G/C cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2562456 0.652 rs62110214 chr19:21775208 G/A cg13978929 chr19:21580086 ZNF493 -0.56 -4.72 -0.39 6.29e-6 Pain; TGCT cis rs3862435 0.610 rs2589942 chr15:90935181 T/C cg14166756 chr15:90894880 ZNF774 -0.28 -4.64 -0.38 8.87e-6 Response to exercise (triglyceride level interaction); TGCT cis rs1843834 0.755 rs10197382 chr2:225574650 T/C cg22455342 chr2:225449267 CUL3 0.66 6.28 0.49 5.25e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs6701037 0.681 rs34370567 chr1:175131340 C/T cg00321850 chr1:175162397 KIAA0040 -0.4 -5.71 -0.46 7.97e-8 Alcohol dependence; TGCT cis rs7582180 0.764 rs7425449 chr2:100928393 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.91 -0.4 2.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.891 rs2281231 chr16:1601879 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.29 -5.33 -0.43 4.51e-7 Coronary artery disease; TGCT cis rs2692947 0.740 rs11695514 chr2:96548068 C/T cg23100626 chr2:96804247 ASTL 0.37 4.44 0.37 1.93e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10892173 0.703 rs1014034 chr11:117661734 G/C cg07621104 chr11:117668040 DSCAML1 0.5 5.06 0.41 1.46e-6 Myopia; TGCT cis rs72945132 0.882 rs56770826 chr11:70128874 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs2075371 0.830 rs1421478 chr7:133922793 T/A cg11752832 chr7:134001865 SLC35B4 0.67 5.53 0.44 1.78e-7 Mean platelet volume; TGCT cis rs2243480 0.803 rs423187 chr7:65509499 G/C cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs13256369 0.950 rs13248096 chr8:8577476 C/T cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs7208859 0.623 rs73267858 chr17:29059737 A/G cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10892173 0.566 rs10892175 chr11:117674355 G/A cg21014159 chr11:117668035 DSCAML1 0.61 5.86 0.47 3.95e-8 Myopia; TGCT cis rs4665809 0.941 rs1434079 chr2:26284670 C/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs35883536 0.584 rs56112014 chr1:101037431 A/G cg10298815 chr1:101004474 GPR88 -0.25 -4.49 -0.37 1.63e-5 Monocyte count; TGCT cis rs459571 0.959 rs2073818 chr9:136918662 C/A cg14405625 chr9:136855902 VAV2 -0.32 -4.79 -0.39 4.71e-6 Platelet distribution width; TGCT cis rs1371867 0.846 rs1788182 chr8:101334620 C/T cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT trans rs986417 0.818 rs761557 chr14:61077484 C/T cg04611801 chr17:56402029 BZRAP1 0.88 7.29 0.55 3.2e-11 Gut microbiota (bacterial taxa); TGCT cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg25660036 chr4:7070649 GRPEL1 -0.64 -5.55 -0.45 1.68e-7 Monocyte percentage of white cells; TGCT cis rs7772486 0.686 rs9390349 chr6:146054430 T/G cg23711669 chr6:146136114 FBXO30 -0.87 -9.51 -0.65 1.94e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs5750830 0.621 rs5757665 chr22:39821641 A/G cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs2816062 0.721 rs2816047 chr1:18893728 A/C cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.01e-27 Urate levels in lean individuals; TGCT cis rs11948739 0.501 rs79115810 chr5:130374516 A/G cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Pediatric bone mineral content (hip); TGCT cis rs11997175 0.716 rs7460818 chr8:33816362 A/G ch.8.33884649F chr8:33765107 NA 0.34 5.28 0.43 5.56e-7 Body mass index; TGCT cis rs950027 0.620 rs1153862 chr15:45631868 A/G cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs10514758 0.744 rs1521564 chr3:114853163 A/G cg05943254 chr3:114009756 NA -0.85 -5.06 -0.41 1.48e-6 Urate levels in obese individuals; TGCT cis rs1865760 0.566 rs3752419 chr6:26027433 C/T cg17042849 chr6:26104293 HIST1H4C -0.6 -5.28 -0.43 5.54e-7 Height; TGCT cis rs4975709 0.589 rs4975747 chr5:1862836 G/A cg12288994 chr5:1860383 NA 0.23 4.57 0.38 1.18e-5 Cardiovascular disease risk factors; TGCT cis rs2276314 0.857 rs59649576 chr18:33616075 G/T cg19628046 chr18:33552617 C18orf21 0.52 4.56 0.38 1.2e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs459571 1.000 rs467387 chr9:136907005 G/A cg14405625 chr9:136855902 VAV2 -0.31 -4.72 -0.39 6.32e-6 Platelet distribution width; TGCT cis rs6912958 0.754 rs4587143 chr6:88292291 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.14e-6 Blood metabolite levels; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg15242686 chr22:24348715 GSTTP1 -0.5 -5.91 -0.47 3.07e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1552244 0.554 rs2272120 chr3:10046703 C/T cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs8062405 1.000 rs3888190 chr16:28889486 C/A cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.9e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs79057730 0.599 rs6951032 chr7:794092 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.7 6.6 0.51 1.1e-9 Initial pursuit acceleration; TGCT cis rs514406 0.644 rs928451 chr1:53195800 A/G cg22166914 chr1:53195759 ZYG11B -0.5 -9.42 -0.65 3.19e-16 Monocyte count; TGCT cis rs933688 1.000 rs7715402 chr5:90679504 T/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.95 8.76 0.62 1.19e-14 Smoking behavior; TGCT cis rs7714584 1.000 rs6874560 chr5:150182713 A/C cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs10504229 1.000 rs76270388 chr8:58195605 T/A cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs7681440 0.904 rs6816469 chr4:90772885 G/C cg26578617 chr4:90757533 SNCA -0.46 -4.73 -0.39 6.01e-6 Dementia with Lewy bodies; TGCT cis rs17331151 0.541 rs11709430 chr3:52862055 G/A cg07884673 chr3:53033167 SFMBT1 0.5 5.97 0.47 2.3e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9910055 0.529 rs368328 chr17:42170289 G/A cg13607699 chr17:42295918 UBTF -0.62 -4.87 -0.4 3.38e-6 Total body bone mineral density; TGCT cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg12667521 chr19:29218732 NA 0.55 5.9 0.47 3.29e-8 Methadone dose in opioid dependence; TGCT cis rs4824093 0.610 rs73441787 chr22:50269646 A/G cg20569369 chr22:51173646 NA 0.28 4.69 0.39 7.23e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1375194 0.582 rs4670735 chr2:33801456 C/T cg04131969 chr2:33951647 MYADML -0.57 -5.03 -0.41 1.65e-6 Response to antidepressants in depression; TGCT cis rs2982552 0.773 rs62442016 chr6:152056053 C/A cg22157087 chr6:152012887 ESR1 0.21 5.17 0.42 8.93e-7 Bone properties (heel); TGCT cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg26531700 chr6:26746687 NA -0.57 -5.21 -0.42 7.62e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11167764 0.895 rs9324865 chr5:141488792 T/C cg08523384 chr5:141488047 NDFIP1 -0.25 -5.37 -0.43 3.72e-7 Crohn's disease; TGCT cis rs7666738 0.830 rs1534318 chr4:98965058 C/T cg05340658 chr4:99064831 C4orf37 0.53 6.04 0.48 1.64e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9291683 0.507 rs6827754 chr4:10018153 A/C cg00071950 chr4:10020882 SLC2A9 -0.59 -4.88 -0.4 3.24e-6 Bone mineral density; TGCT cis rs13191362 1.000 rs35044651 chr6:163004142 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2153535 0.580 rs9328488 chr6:8529411 G/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs12497850 0.931 rs4974085 chr3:48924900 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs3096299 0.967 rs3102341 chr16:89450744 G/A cg02187348 chr16:89574699 SPG7 0.49 4.6 0.38 1.04e-5 Multiple myeloma (IgH translocation); TGCT cis rs9649213 0.614 rs4236537 chr7:97996593 T/C cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.73 -0.62 1.45e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs1903068 0.925 rs1551642 chr4:55994210 T/C cg09978860 chr4:56023921 NA 0.58 6.38 0.5 3.16e-9 Endometriosis; TGCT cis rs11677370 1.000 rs11677370 chr2:3841420 T/A cg17052675 chr2:3827356 NA -0.28 -4.73 -0.39 5.9e-6 Type 2 diabetes; TGCT cis rs875971 0.895 rs6460300 chr7:65952924 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs2050392 0.624 rs303450 chr10:30725337 C/A cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs2562456 0.561 rs12610883 chr19:21750059 A/G cg01304269 chr19:21688519 ZNF429 0.58 4.73 0.39 5.93e-6 Pain; TGCT cis rs9549260 0.564 rs9549270 chr13:41284193 G/T cg21288729 chr13:41239152 FOXO1 0.86 7.76 0.57 2.68e-12 Red blood cell count; TGCT cis rs4654899 0.931 rs4654730 chr1:21229286 A/T cg01072550 chr1:21505969 NA -0.49 -7.94 -0.58 1.03e-12 Superior frontal gyrus grey matter volume; TGCT trans rs7864133 1.000 rs11139251 chr9:84063141 A/G cg23451063 chr7:1059876 C7orf50 0.55 6.93 0.53 2.02e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs28714278 0.609 rs12899936 chr15:40298068 G/A cg21830797 chr15:40226279 EIF2AK4 -0.52 -4.66 -0.39 7.94e-6 Mean corpuscular hemoglobin; TGCT cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.09 13.7 0.78 1.38e-26 Height; TGCT cis rs3821902 0.597 rs73119079 chr3:64015399 G/A cg22134162 chr3:63841271 THOC7 -0.32 -4.73 -0.39 6.09e-6 Breast cancer; TGCT cis rs4819052 0.684 rs914216 chr21:46698298 T/G cg06618935 chr21:46677482 NA -0.37 -5.64 -0.45 1.1e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13102973 0.682 rs11938038 chr4:135894258 T/C cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs4642101 0.686 rs9822382 chr3:12828828 T/G cg05775895 chr3:12838266 CAND2 0.78 8.9 0.62 5.77e-15 QRS complex (12-leadsum); TGCT trans rs7618501 0.699 rs9862795 chr3:49915506 A/T cg21659725 chr3:3221576 CRBN 0.78 9.34 0.64 4.99e-16 Intelligence (multi-trait analysis); TGCT cis rs11190604 1.000 rs10883503 chr10:102275504 C/A cg16342193 chr10:102329863 NA -0.44 -5.65 -0.45 1.06e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.830 rs6819177 chr4:99040907 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs155076 0.938 rs9509630 chr13:21844314 G/A cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs9611519 0.780 rs9611542 chr22:41677317 C/T cg06634786 chr22:41940651 POLR3H -0.63 -5.84 -0.46 4.26e-8 Neuroticism; TGCT cis rs6570726 0.846 rs6914304 chr6:145921017 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.59 0.38 1.07e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10744422 0.764 rs6489241 chr12:123288739 C/G cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs651907 0.557 rs13077925 chr3:101488181 T/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.51 0.69 7.46e-19 Colorectal cancer; TGCT cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs6121246 0.529 rs6060145 chr20:30178631 T/C cg13852791 chr20:30311386 BCL2L1 0.71 4.54 0.38 1.31e-5 Mean corpuscular hemoglobin; TGCT cis rs13108904 0.517 rs7671242 chr4:1339875 G/A cg03303774 chr4:1407052 NA 0.35 5.41 0.44 3.17e-7 Obesity-related traits; TGCT cis rs9581857 0.685 rs9319373 chr13:28042835 A/G cg22138327 chr13:27999177 GTF3A 0.68 4.57 0.38 1.14e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9814567 1.000 rs62271514 chr3:134298554 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.92 8.42 0.6 7.71e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6952808 0.895 rs12669518 chr7:1921429 G/C cg22963979 chr7:1858916 MAD1L1 -0.35 -5.51 -0.44 2.01e-7 Bipolar disorder and schizophrenia; TGCT cis rs17608059 0.679 rs9898056 chr17:13951966 C/G cg11395062 chr17:14139857 CDRT15 0.39 5.08 0.41 1.36e-6 Temperament; TGCT cis rs9733 0.596 rs72702556 chr1:150680115 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs739496 0.579 rs12423041 chr12:112324846 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.44 0.44 2.7e-7 Platelet count; TGCT cis rs782590 1.000 rs782594 chr2:55844445 T/C cg03859395 chr2:55845619 SMEK2 0.92 11.37 0.71 5.88e-21 Metabolic syndrome; TGCT cis rs10504229 1.000 rs59275611 chr8:58195191 G/A cg24829409 chr8:58192753 C8orf71 -0.55 -4.79 -0.39 4.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs7681440 1.000 rs1471483 chr4:90754292 A/G cg14346243 chr4:90757452 SNCA -0.57 -5.37 -0.43 3.77e-7 Dementia with Lewy bodies; TGCT cis rs1371867 0.817 rs1788208 chr8:101312515 T/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs10791097 0.694 rs4457753 chr11:130755575 A/G cg12179176 chr11:130786555 SNX19 0.83 10.36 0.68 1.73e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7666738 0.544 rs35160902 chr4:98974690 A/T cg05340658 chr4:99064831 C4orf37 0.51 5.83 0.46 4.56e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs35306767 0.807 rs34885925 chr10:919032 G/C cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs7829975 0.714 rs4841042 chr8:8664622 A/G cg15556689 chr8:8085844 FLJ10661 -0.67 -6.23 -0.49 6.75e-9 Mood instability; TGCT cis rs7681440 0.904 rs58864428 chr4:90766986 T/C cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs9921222 1.000 rs9921222 chr16:375782 A/G cg00101154 chr16:420108 MRPL28 0.57 6.84 0.52 3.28e-10 Bone mineral density (spine);Bone mineral density; TGCT cis rs7524258 0.868 rs8179413 chr1:7267729 T/G cg07173049 chr1:7289937 CAMTA1 0.31 5.29 0.43 5.39e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7727544 0.735 rs272867 chr5:131681057 G/A cg24060327 chr5:131705240 SLC22A5 -0.56 -6.26 -0.49 5.61e-9 Blood metabolite levels; TGCT cis rs9381040 0.674 rs3747742 chr6:41162518 C/T cg03526776 chr6:41159608 TREML2 -0.28 -5.68 -0.45 9.15e-8 Alzheimer's disease (late onset); TGCT cis rs17473412 0.677 rs9327298 chr5:122850321 G/A cg15125798 chr5:122621645 NA -0.57 -5.2 -0.42 8.05e-7 Total body bone mineral density; TGCT cis rs11190604 1.000 rs10786598 chr10:102291579 G/A cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.5 5.34 0.43 4.3e-7 Lymphocyte counts; TGCT cis rs4434138 0.568 rs6414569 chr3:52708075 A/T cg07507251 chr3:52567010 NT5DC2 0.48 6.59 0.51 1.11e-9 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.933 rs2879087 chr5:140188575 G/C cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7824557 0.614 rs2736286 chr8:11227104 A/G cg21775007 chr8:11205619 TDH -0.69 -6.92 -0.53 2.1e-10 Retinal vascular caliber; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg12419862 chr22:24373484 LOC391322 -0.8 -8.67 -0.61 1.97e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3784262 1.000 rs4646622 chr15:58257199 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.7 -0.57 3.78e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7586879 0.593 rs11689546 chr2:25130451 A/G cg15423357 chr2:25149977 NA 0.5 4.88 0.4 3.13e-6 Body mass index; TGCT cis rs10782582 0.609 rs1796827 chr1:76391536 A/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.53 4.66 0.39 7.96e-6 Daytime sleep phenotypes; TGCT cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.536 rs7165025 chr15:76766434 G/A cg26408565 chr15:76604113 ETFA -0.37 -4.99 -0.41 2.03e-6 Blood metabolite levels; TGCT cis rs6089584 0.888 rs6061405 chr20:60617033 A/G cg13770153 chr20:60521292 NA -0.54 -7.13 -0.54 7.45e-11 Body mass index; TGCT cis rs7666738 0.546 rs62320963 chr4:98839297 A/G cg05340658 chr4:99064831 C4orf37 0.55 6.01 0.48 1.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1371867 0.875 rs1612773 chr8:101337818 G/C cg00191853 chr8:101177733 SPAG1 -0.23 -4.68 -0.39 7.34e-6 Atrioventricular conduction; TGCT cis rs727563 0.565 rs132774 chr22:42031953 C/G cg17554472 chr22:41940697 POLR3H -0.47 -5.04 -0.41 1.61e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg11941060 chr3:133502564 NA -0.27 -5.42 -0.44 2.94e-7 Iron status biomarkers; TGCT cis rs35264875 1.000 rs35264875 chr11:68846399 A/T cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs2153535 0.580 rs4365970 chr6:8453813 C/T cg07606381 chr6:8435919 SLC35B3 -0.51 -4.86 -0.4 3.45e-6 Motion sickness; TGCT cis rs1799949 0.859 rs11657004 chr17:41442751 A/G cg05368731 chr17:41323189 NBR1 1.16 14.14 0.79 1.28e-27 Menopause (age at onset); TGCT cis rs12142240 0.659 rs17361873 chr1:46832686 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.8 -0.4 4.46e-6 Menopause (age at onset); TGCT cis rs9303401 0.659 rs17822735 chr17:56620167 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.85 0.47 4.05e-8 Height; TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg08280861 chr8:58055591 NA 0.55 6.23 0.49 6.59e-9 Developmental language disorder (linguistic errors); TGCT cis rs3935685 0.874 rs28406214 chr15:77996537 G/A cg25212270 chr15:78015279 NA 0.26 5.61 0.45 1.23e-7 Intelligence (multi-trait analysis); TGCT cis rs13394619 1.000 rs2884374 chr2:11731846 C/T cg07314298 chr2:11723111 GREB1 0.29 5.12 0.42 1.14e-6 Endometriosis; TGCT cis rs7666738 0.830 rs6825211 chr4:98807698 A/T cg05340658 chr4:99064831 C4orf37 0.49 5.75 0.46 6.46e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4713118 0.955 rs9368528 chr6:27683798 G/A cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT trans rs551517 0.541 rs1751242 chr9:113641783 T/A cg18410444 chr5:89825535 LYSMD3 0.66 6.73 0.52 5.51e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs6969780 1.000 rs6461985 chr7:27150634 T/C cg04317399 chr7:27170313 HOXA4 0.45 4.47 0.37 1.77e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7772486 0.714 rs1883365 chr6:146076749 C/T cg23711669 chr6:146136114 FBXO30 -0.88 -9.63 -0.65 1.01e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.614 rs34550282 chr17:57092788 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.87 0.47 3.77e-8 Cognitive test performance; TGCT cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg06028808 chr11:68637592 NA 0.53 6.86 0.52 2.9e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs67478160 0.595 rs12879501 chr14:104272634 G/T cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs6500602 0.963 rs7201012 chr16:4480682 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.19 0.42 8.2e-7 Schizophrenia; TGCT cis rs7772486 0.521 rs9485017 chr6:146023326 C/T cg05347473 chr6:146136440 FBXO30 0.61 5.76 0.46 6.18e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs4699592 chr4:98974202 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9467603 1.000 rs1892250 chr6:25769024 T/C cg16898833 chr6:26189333 HIST1H4D -0.99 -4.75 -0.39 5.62e-6 Intelligence (multi-trait analysis); TGCT cis rs79057730 0.599 rs4721086 chr7:821123 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.73 5.59 0.45 1.36e-7 Initial pursuit acceleration; TGCT cis rs9467773 1.000 rs1056667 chr6:26510564 T/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs13185784 0.667 rs4700924 chr5:179645870 A/C cg04734276 chr5:178882605 NA 0.29 4.46 0.37 1.79e-5 TRAIL levels; TGCT cis rs910187 0.605 rs6063079 chr20:45804275 C/G cg27589058 chr20:45804311 EYA2 -0.36 -8.65 -0.61 2.2e-14 Migraine; TGCT cis rs2439831 0.867 rs28461955 chr15:43661459 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs7829975 0.688 rs7826660 chr8:8379107 C/A cg08975724 chr8:8085496 FLJ10661 0.64 6.03 0.48 1.77e-8 Mood instability; TGCT cis rs10791323 0.604 rs2851116 chr11:133705759 G/A cg15485101 chr11:133734466 NA 0.41 5.18 0.42 8.59e-7 Childhood ear infection; TGCT cis rs12541335 0.639 rs11135995 chr8:22200148 C/T cg02788857 chr8:22132959 PIWIL2 -0.26 -4.87 -0.4 3.26e-6 Hypertriglyceridemia; TGCT cis rs7666738 0.830 rs13133355 chr4:98919415 A/G cg05340658 chr4:99064831 C4orf37 0.53 6.12 0.48 1.13e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2456568 0.771 rs8181530 chr11:93638678 G/A cg16099599 chr11:93583650 C11orf90 -0.4 -5.12 -0.42 1.13e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4819052 0.851 rs3673 chr21:46681775 C/T cg06618935 chr21:46677482 NA -0.36 -5.39 -0.44 3.38e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs36051895 0.623 rs7043634 chr9:5263146 G/A cg02405213 chr9:5042618 JAK2 -0.72 -9.47 -0.65 2.37e-16 Pediatric autoimmune diseases; TGCT cis rs7000551 0.556 rs13258367 chr8:22235759 C/A cg12081754 chr8:22256438 SLC39A14 0.32 4.96 0.41 2.23e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs377070 0.934 rs309407 chr4:123619335 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.48 5.32 0.43 4.61e-7 Mosquito bite size; TGCT cis rs9393692 0.645 rs2179152 chr6:26325888 T/C cg00631329 chr6:26305371 NA -0.46 -6.91 -0.53 2.23e-10 Educational attainment; TGCT cis rs1395 1.000 rs1275501 chr2:27419282 A/C cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.5 -6.65 -0.51 8.47e-10 Blood metabolite levels; TGCT cis rs71435601 0.628 rs563696 chr2:21389430 T/A cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.33e-9 Electroencephalogram traits; TGCT cis rs12477438 0.520 rs11123763 chr2:99750673 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg23758822 chr17:41437982 NA 0.72 6.77 0.52 4.51e-10 Menopause (age at onset); TGCT cis rs12579753 0.917 rs10129029 chr12:82180324 G/A cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs9549367 0.713 rs3024776 chr13:113827075 A/G cg00898013 chr13:113819073 PROZ 0.57 7.24 0.55 4.08e-11 Platelet distribution width; TGCT cis rs6088580 0.634 rs2184836 chr20:32963369 A/G cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs2576037 0.583 rs1970668 chr18:44523220 A/G cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.68 -0.39 7.26e-6 Personality dimensions; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg02953382 chr22:24373134 LOC391322 -0.82 -9.12 -0.63 1.73e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9902453 0.904 rs7213076 chr17:28419428 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -7.31 -0.55 2.88e-11 Coffee consumption (cups per day); TGCT cis rs9611565 0.921 rs2281332 chr22:41746212 T/C cg03806693 chr22:41940476 POLR3H -0.87 -9.3 -0.64 6.07e-16 Vitiligo; TGCT cis rs17331151 0.573 rs28552648 chr3:52865593 G/A cg11137980 chr3:52469226 SEMA3G 0.29 5.14 0.42 1.04e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6951245 0.542 rs28460147 chr7:1217192 G/A cg03188948 chr7:1209495 NA 0.71 6.11 0.48 1.18e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg11494091 chr17:61959527 GH2 -0.53 -11.85 -0.73 4e-22 Prudent dietary pattern; TGCT cis rs7829975 0.508 rs1594437 chr8:8825875 T/C cg11995313 chr8:8860691 ERI1 -0.56 -4.95 -0.41 2.35e-6 Mood instability; TGCT cis rs11098499 1.000 rs7659194 chr4:120207147 T/G cg09307838 chr4:120376055 NA 0.49 4.47 0.37 1.78e-5 Corneal astigmatism; TGCT cis rs2404602 0.669 rs12916324 chr15:77179603 G/A cg26408565 chr15:76604113 ETFA -0.36 -4.52 -0.38 1.41e-5 Blood metabolite levels; TGCT cis rs4862750 0.915 rs6835681 chr4:187903476 A/G cg10295955 chr4:187884368 NA -0.97 -14.89 -0.8 2.14e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs1215050 0.740 rs1084784 chr4:98961711 T/G cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.12e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs4285028 0.747 rs9852845 chr3:121390618 A/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs3617 0.573 rs12638968 chr3:52919447 T/A cg10802521 chr3:52805072 NEK4 0.57 6.57 0.51 1.27e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg20637647 chr7:64974828 NA 0.91 5.09 0.42 1.29e-6 Diabetic kidney disease; TGCT cis rs4253772 0.513 rs6008700 chr22:46722560 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.69 5.31 0.43 4.82e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs7945705 0.902 rs1560569 chr11:8939887 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.48 -5.44 -0.44 2.75e-7 Hemoglobin concentration; TGCT cis rs2242116 0.796 rs4683297 chr3:46973673 T/C cg27129171 chr3:47204927 SETD2 -0.64 -6.32 -0.49 4.39e-9 Birth weight; TGCT trans rs6951245 0.554 rs76243429 chr7:1152543 C/T cg13565492 chr6:43139072 SRF -0.81 -7.66 -0.57 4.5e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2050392 0.557 rs306588 chr10:30723593 G/A cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT cis rs4936891 0.563 rs78158860 chr11:123890220 A/G cg22125253 chr11:123886957 OR10G4 0.21 4.74 0.39 5.66e-6 Male fertility; TGCT cis rs7666738 0.830 rs13137808 chr4:99047095 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs938554 0.513 rs3775946 chr4:9995256 A/G cg02734326 chr4:10020555 SLC2A9 0.52 4.8 0.4 4.41e-6 Blood metabolite levels; TGCT cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg15659132 chr6:26577336 NA 0.87 11.0 0.7 4.77e-20 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.870 rs12369578 chr12:38444227 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.59 0.56 6.74e-12 Bladder cancer; TGCT cis rs362272 0.545 rs3129308 chr4:3309272 C/T cg18352616 chr4:3374830 RGS12 0.27 5.49 0.44 2.19e-7 Serum sulfate level; TGCT cis rs1812835 1 rs1812835 chr15:73507504 C/A cg25046953 chr15:73611614 NA 0.25 4.6 0.38 1.03e-5 Heart rate variability traits (RMSSD);Heart rate variability traits (pvRSA/HF);Heart rate variability traits (SDNN); TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs28728124 chr4:99001116 G/T cg18180107 chr4:99064573 C4orf37 0.51 4.53 0.38 1.38e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs68170813 0.559 rs12532967 chr7:106937418 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs1371867 0.875 rs962451 chr8:101331010 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs3820068 0.532 rs72645862 chr1:15920366 A/G cg05660106 chr1:15850417 CASP9 0.84 8.27 0.6 1.8e-13 Systolic blood pressure; TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.51 -4.48 -0.37 1.66e-5 Prudent dietary pattern; TGCT cis rs10080237 0.564 rs2490224 chr6:80809833 G/A cg08355045 chr6:80787529 NA 0.33 5.52 0.44 1.91e-7 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals; TGCT cis rs10927875 0.691 rs1048302 chr1:16340879 T/G cg21385522 chr1:16154831 NA 0.6 6.34 0.49 3.95e-9 Dilated cardiomyopathy; TGCT cis rs12477438 0.520 rs6741773 chr2:99738962 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.85 8.41 0.6 8.43e-14 Chronic sinus infection; TGCT cis rs1532993 0.518 rs2865936 chr4:98553780 C/T cg05340658 chr4:99064831 C4orf37 -0.38 -4.53 -0.38 1.36e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9660992 0.710 rs7367930 chr1:205235512 A/G cg00857998 chr1:205179979 DSTYK 0.51 4.47 0.37 1.73e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs11874712 0.966 rs8094902 chr18:43666774 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs28595532 0.841 rs114966236 chr4:119733437 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs9393692 0.905 rs6931391 chr6:26279235 G/C cg13736514 chr6:26305472 NA -0.41 -5.77 -0.46 6.09e-8 Educational attainment; TGCT cis rs4820539 1.000 rs4822362 chr22:23482744 C/A cg14186256 chr22:23484241 RTDR1 0.98 12.77 0.75 2.31e-24 Bone mineral density; TGCT cis rs11264213 0.901 rs72661636 chr1:36426483 T/C cg27506609 chr1:36549197 TEKT2 0.41 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs7824557 0.651 rs6601582 chr8:11207367 C/A cg21775007 chr8:11205619 TDH 0.73 7.14 0.54 7.09e-11 Retinal vascular caliber; TGCT cis rs853679 0.517 rs9393895 chr6:28127621 T/C cg12963246 chr6:28129442 ZNF389 0.53 5.19 0.42 8.46e-7 Depression; TGCT cis rs10992471 0.676 rs13286566 chr9:95473178 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.48 -0.44 2.27e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2354432 0.607 rs9782976 chr1:146825049 A/G cg25205988 chr1:146714368 CHD1L 1.21 7.2 0.54 5.05e-11 Mitochondrial DNA levels; TGCT cis rs6840360 0.550 rs6836343 chr4:152497564 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs7216064 1.000 rs9897982 chr17:65879592 G/T cg12091567 chr17:66097778 LOC651250 -0.84 -6.8 -0.52 4.01e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7917772 0.582 rs4917976 chr10:104360518 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.36 -0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs478304 0.654 rs7947604 chr11:65442059 G/C cg17480646 chr11:65405466 SIPA1 -0.62 -8.13 -0.59 3.73e-13 Acne (severe); TGCT cis rs7267979 0.789 rs1983974 chr20:25530619 A/C cg03522245 chr20:25566470 NINL -0.56 -5.74 -0.46 6.76e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9357506 1.000 rs935106 chr6:46304657 G/A cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.37e-7 Body mass index; TGCT cis rs28374715 0.662 rs72737792 chr15:41515589 G/C cg18705301 chr15:41695430 NDUFAF1 -0.78 -10.91 -0.7 7.59e-20 Ulcerative colitis; TGCT cis rs12458462 0.892 rs58675823 chr18:77463672 G/A cg11879182 chr18:77439856 CTDP1 0.71 7.86 0.58 1.61e-12 Monocyte count; TGCT cis rs1865760 0.532 rs2006736 chr6:26086017 C/T cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs1005277 0.540 rs289638 chr10:37923731 G/A cg25427524 chr10:38739819 LOC399744 -0.36 -7.13 -0.54 7.28e-11 Extrinsic epigenetic age acceleration; TGCT trans rs916888 0.821 rs199513 chr17:44856932 A/G cg22968622 chr17:43663579 NA -1.09 -9.69 -0.66 7.23e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs67311347 1.000 rs4973993 chr3:40452960 T/C cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs7926906 0.631 rs6483075 chr11:90520310 C/T cg26138821 chr11:89956704 CHORDC1 -0.48 -4.91 -0.4 2.76e-6 Intelligence (multi-trait analysis); TGCT cis rs2197308 0.740 rs11182967 chr12:37935140 A/C cg13010199 chr12:38710504 ALG10B 0.66 5.33 0.43 4.41e-7 Morning vs. evening chronotype; TGCT cis rs9486719 1.000 rs12193732 chr6:96942609 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs68170813 0.559 rs76299183 chr7:106904859 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs7119 0.604 rs2458035 chr15:77862806 G/A cg27398640 chr15:77910606 LINGO1 0.27 4.78 0.39 4.84e-6 Type 2 diabetes; TGCT cis rs13242816 1.000 rs987791 chr7:116134701 A/G cg16553024 chr7:116138462 CAV2 -0.45 -5.06 -0.41 1.49e-6 P wave duration; TGCT cis rs10804591 1.000 rs2625984 chr3:129339101 A/G cg07730360 chr3:128845626 NA 0.2 4.62 0.38 9.34e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6725041 0.819 rs1546718 chr2:213088329 A/G cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs7617773 0.780 rs13079728 chr3:48339360 A/G cg11946769 chr3:48343235 NME6 0.82 7.06 0.54 1.03e-10 Coronary artery disease; TGCT cis rs1862618 0.525 rs2662019 chr5:56263104 A/G cg24531977 chr5:56204891 C5orf35 0.77 6.8 0.52 3.94e-10 Initial pursuit acceleration; TGCT cis rs62064224 0.593 rs916663 chr17:30835833 A/C cg24550644 chr17:30846204 MYO1D 0.43 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg27535305 chr1:53392650 SCP2 0.28 5.71 0.46 8.04e-8 Monocyte count; TGCT cis rs10791097 0.609 rs3751039 chr11:130773076 A/G cg12179176 chr11:130786555 SNX19 -0.92 -11.98 -0.73 1.88e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs931812 0.895 rs4236763 chr8:101913022 G/A cg20993868 chr7:22813445 NA 0.4 8.7 0.62 1.66e-14 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs9291683 0.595 rs35250962 chr4:10048271 C/T cg11266682 chr4:10021025 SLC2A9 0.65 8.87 0.62 6.58e-15 Bone mineral density; TGCT trans rs17685 0.664 rs9801113 chr7:75792031 C/T cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT trans rs877282 0.898 rs11253340 chr10:764786 G/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg08736216 chr1:53307985 ZYG11A -0.3 -5.99 -0.47 2.09e-8 Monocyte count; TGCT cis rs9303401 0.659 rs16943176 chr17:56769887 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs2658782 1.000 rs2658781 chr11:93166368 C/T cg18152523 chr11:93063302 CCDC67 0.55 4.8 0.4 4.49e-6 Pulmonary function decline; TGCT cis rs9549367 0.774 rs9549364 chr13:113903745 T/C cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs713587 0.571 rs564667 chr2:25310860 A/T cg01884057 chr2:25150051 NA -0.25 -4.81 -0.4 4.36e-6 Body mass index in non-asthmatics; TGCT trans rs62103177 0.564 rs2115996 chr18:77701007 C/G cg05926928 chr17:57297772 GDPD1 0.98 8.96 0.63 4.08e-15 Opioid sensitivity; TGCT trans rs1814175 0.817 rs7924619 chr11:49620632 G/A cg15704280 chr7:45808275 SEPT13 -0.73 -8.64 -0.61 2.32e-14 Height; TGCT cis rs9611565 0.592 rs5758427 chr22:42099688 A/G cg03806693 chr22:41940476 POLR3H 1.06 11.92 0.73 2.7e-22 Vitiligo; TGCT trans rs9388451 0.839 rs4897157 chr6:126102981 A/T cg05039488 chr6:79577232 IRAK1BP1 -0.72 -8.04 -0.59 6.03e-13 Brugada syndrome; TGCT cis rs2288884 0.806 rs11084141 chr19:52587907 G/A cg13540795 chr19:52551618 ZNF432 -0.64 -5.42 -0.44 2.98e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs7843479 0.898 rs13282562 chr8:21869727 G/A cg17168535 chr8:21777572 XPO7 0.62 5.62 0.45 1.18e-7 Mean corpuscular volume; TGCT cis rs244731 1.000 rs244730 chr5:176539212 A/G cg16006841 chr5:176797999 RGS14 -0.48 -6.3 -0.49 4.7e-9 Urate levels in lean individuals; TGCT cis rs13256369 0.901 rs12679831 chr8:8566411 T/G cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs73252553 0.513 rs315684 chr4:25374197 A/G cg04009456 chr4:25379436 ANAPC4 0.42 4.72 0.39 6.24e-6 Cannabis dependence symptom count; TGCT cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs4665630 0.522 rs1862902 chr2:23886622 A/C cg08063864 chr2:24346004 PFN4;LOC375190 -1.13 -5.45 -0.44 2.64e-7 Hypertension; TGCT cis rs3125734 0.660 rs10733769 chr10:63974255 G/T cg05499367 chr10:63213510 TMEM26 -0.35 -4.73 -0.39 6.06e-6 Rheumatoid arthritis; TGCT cis rs3751972 0.911 rs11657699 chr17:26242726 C/G cg02948944 chr17:26242737 NA 0.48 6.79 0.52 4.09e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs56309584 0.596 rs117854193 chr17:8178467 G/A cg08322244 chr17:8066669 VAMP2 -0.57 -5.31 -0.43 4.89e-7 Initial pursuit acceleration; TGCT cis rs7267979 0.899 rs442834 chr20:25458096 A/G cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8064299 0.967 rs880827 chr17:72767435 C/T cg25054828 chr17:72772726 NAT9;TMEM104 -0.76 -7.6 -0.56 6.16e-12 Monocyte count; TGCT cis rs7843479 0.582 rs7818254 chr8:21798316 C/T cg17168535 chr8:21777572 XPO7 0.81 8.33 0.6 1.25e-13 Mean corpuscular volume; TGCT cis rs259282 0.584 rs10416758 chr19:33107716 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.53 4.82 0.4 4.09e-6 Schizophrenia; TGCT cis rs76878669 0.538 rs4930360 chr11:66143247 T/A cg18002602 chr11:66138449 SLC29A2 0.54 6.62 0.51 9.7e-10 Educational attainment (years of education); TGCT trans rs17471911 0.708 rs9633708 chr10:100807933 G/A cg03484267 chr2:207988651 KLF7 -0.52 -6.67 -0.51 7.53e-10 Neuroticism; TGCT cis rs10751667 1.000 rs7396366 chr11:986185 C/A cg06064525 chr11:970664 AP2A2 -0.32 -6.43 -0.5 2.45e-9 Alzheimer's disease (late onset); TGCT cis rs3806843 0.576 rs246029 chr5:140333226 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg13012494 chr21:47604986 C21orf56 0.39 4.77 0.39 5.19e-6 Testicular germ cell tumor; TGCT cis rs6688613 0.685 rs61815130 chr1:166910465 T/C cg07049167 chr1:166818506 POGK 0.25 5.15 0.42 9.73e-7 Refractive astigmatism; TGCT cis rs1801251 1.000 rs36007169 chr2:233621834 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs1372520 0.684 rs2619341 chr4:90741773 A/G cg01966878 chr4:90757139 SNCA -0.3 -4.69 -0.39 7.05e-6 Neuroticism; TGCT cis rs35146811 0.731 rs2257213 chr7:99810113 T/C cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs7809950 0.861 rs2701682 chr7:107295835 G/A cg23024343 chr7:107201750 COG5 0.43 5.98 0.47 2.23e-8 Coronary artery disease; TGCT cis rs10876993 0.928 rs1689596 chr12:58053029 T/C cg15848620 chr12:58087721 OS9 -0.72 -5.86 -0.47 3.95e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs10934753 0.632 rs2001273 chr3:125926110 C/T cg01346077 chr3:125931526 NA 0.37 6.11 0.48 1.21e-8 Plasma homocysteine levels (post-methionine load test); TGCT cis rs56104184 0.723 rs116909499 chr19:49407733 C/T cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2816062 0.813 rs2745323 chr1:18882385 C/T cg18795169 chr1:18902165 NA -0.59 -13.16 -0.76 2.73e-25 Urate levels in lean individuals; TGCT cis rs6191 0.838 rs6877893 chr5:142727193 C/T cg17617527 chr5:142782415 NR3C1 -0.48 -4.6 -0.38 1.03e-5 Night sleep phenotypes; TGCT cis rs7193541 0.965 rs7199068 chr16:74698263 C/G cg01733217 chr16:74700730 RFWD3 0.83 7.92 0.58 1.13e-12 Multiple myeloma; TGCT cis rs4077468 0.963 rs1342064 chr1:205913073 T/C cg24503407 chr1:205819492 PM20D1 -0.39 -4.57 -0.38 1.14e-5 Cystic fibrosis-related diabetes; TGCT cis rs6448317 1.000 rs11934149 chr4:24938953 T/C cg21108841 chr4:24914750 CCDC149 -0.65 -4.95 -0.41 2.33e-6 Heschl's gyrus morphology; TGCT cis rs7020830 0.931 rs7851239 chr9:37138672 A/G cg14294708 chr9:37120828 ZCCHC7 -1.26 -13.54 -0.77 3.27e-26 Schizophrenia; TGCT cis rs2456568 0.570 rs1827932 chr11:93663319 A/T cg17595323 chr11:93583763 C11orf90 -0.43 -5.34 -0.43 4.33e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs875971 1.000 rs1981798 chr7:65954903 G/T cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs4455778 0.538 rs9642332 chr7:49113177 T/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7226408 0.857 rs55752284 chr18:34447175 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs4253772 0.530 rs9615349 chr22:46732418 T/G cg24881330 chr22:46731750 TRMU 0.96 4.7 0.39 6.75e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs782590 0.935 rs2586954 chr2:55892261 A/C cg03859395 chr2:55845619 SMEK2 0.89 10.38 0.68 1.49e-18 Metabolic syndrome; TGCT cis rs763014 0.898 rs1045277 chr16:633125 T/C cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs2839186 0.814 rs13052376 chr21:47707403 G/C cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs9814567 0.806 rs4955534 chr3:134319723 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs904251 0.600 rs9380673 chr6:37415125 T/C cg25019722 chr6:37503610 NA -0.46 -6.86 -0.52 2.94e-10 Cognitive performance; TGCT cis rs6089829 0.962 rs6011548 chr20:61666063 C/T cg18188782 chr20:61659543 NA 0.46 5.55 0.45 1.61e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs6495122 0.699 rs2168518 chr15:75081078 G/A cg10253484 chr15:75165896 SCAMP2 -0.68 -6.01 -0.48 1.87e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs4742903 0.904 rs7028408 chr9:106859811 G/A cg21169611 chr9:106856078 SMC2 0.49 4.6 0.38 1.03e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs250677 0.687 rs250666 chr5:148454622 A/G cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs4713675 0.553 rs943465 chr6:33731663 G/A cg13859433 chr6:33739653 LEMD2 -0.3 -4.65 -0.39 8.23e-6 Plateletcrit; TGCT cis rs116095464 0.558 rs6869925 chr5:264036 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs314370 0.951 rs3757868 chr7:100482720 G/A cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs7208859 0.673 rs8077116 chr17:29140162 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9486715 1.000 rs9373985 chr6:97063522 C/G cg18709589 chr6:96969512 KIAA0776 -0.77 -7.12 -0.54 7.74e-11 Headache; TGCT cis rs1218582 0.772 rs6683557 chr1:154852307 C/G cg24250549 chr1:154909240 PMVK 0.65 6.46 0.5 2.11e-9 Prostate cancer; TGCT cis rs2842992 0.747 rs1547093 chr6:160205991 C/A cg11366901 chr6:160182831 ACAT2 1.07 7.21 0.54 4.75e-11 Age-related macular degeneration (geographic atrophy); TGCT cis rs10883723 0.810 rs10786669 chr10:104256094 C/G cg05855489 chr10:104503620 C10orf26 -0.57 -4.96 -0.41 2.29e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs61931739 0.500 rs7137392 chr12:34447074 T/C cg06521331 chr12:34319734 NA -0.28 -4.51 -0.38 1.47e-5 Morning vs. evening chronotype; TGCT cis rs6767049 0.528 rs17006724 chr3:20231788 A/G cg00235661 chr3:20228976 SGOL1 0.32 4.93 0.4 2.58e-6 Temperament (bipolar disorder); TGCT cis rs2562456 0.958 rs2562508 chr19:21726281 G/A cg25650185 chr19:21324782 ZNF431 0.64 5.7 0.46 8.3e-8 Pain; TGCT cis rs2204008 0.653 rs11182569 chr12:38572452 G/A cg26384229 chr12:38710491 ALG10B 0.89 8.1 0.59 4.28e-13 Bladder cancer; TGCT cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg03806693 chr22:41940476 POLR3H -1.01 -11.18 -0.71 1.71e-20 Vitiligo; TGCT cis rs427394 0.632 rs169285 chr5:6736587 G/C cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs11690935 0.885 rs6752812 chr2:172851502 C/A cg13550731 chr2:172543902 DYNC1I2 -0.89 -7.89 -0.58 1.33e-12 Schizophrenia; TGCT cis rs5757676 1.000 rs5757676 chr22:39841700 T/C cg11247378 chr22:39784982 NA -0.73 -7.55 -0.56 8.36e-12 IgG glycosylation; TGCT cis rs4273100 0.605 rs28591622 chr17:19175317 A/G cg03910582 chr17:19030146 GRAPL 0.51 6.15 0.48 9.7e-9 Schizophrenia; TGCT cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs13191362 1.000 rs13220048 chr6:163004325 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.86 -10.09 -0.67 7.49e-18 Prudent dietary pattern; TGCT cis rs11190604 1.000 rs11190557 chr10:102209369 G/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7552404 1.000 rs437298 chr1:76113770 T/C cg03433033 chr1:76189801 ACADM -0.84 -10.0 -0.67 1.28e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs523522 0.962 rs10849753 chr12:120910813 C/T cg12219531 chr12:120966889 COQ5 0.83 7.25 0.55 4.02e-11 High light scatter reticulocyte count; TGCT cis rs6831352 0.879 rs2602879 chr4:100040652 G/A cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Alcohol dependence; TGCT cis rs208520 0.874 rs208470 chr6:66916402 G/A cg07460842 chr6:66804631 NA -0.9 -9.16 -0.64 1.34e-15 Exhaled nitric oxide output; TGCT cis rs11252926 0.574 rs7068976 chr10:453112 A/G cg13477178 chr10:375248 DIP2C -0.25 -4.72 -0.39 6.33e-6 Psychosis in Alzheimer's disease; TGCT cis rs7973719 0.868 rs12825629 chr12:7355583 T/C cg07052231 chr12:7363540 PEX5 0.36 5.6 0.45 1.34e-7 IgG glycosylation; TGCT cis rs9467711 0.560 rs6900665 chr6:26487169 C/T cg16898833 chr6:26189333 HIST1H4D 0.94 4.58 0.38 1.12e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs1538970 1.000 rs4660853 chr1:45849090 C/T cg05343316 chr1:45956843 TESK2 0.66 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs13191362 1.000 rs13207671 chr6:162979056 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2180341 0.814 rs9321085 chr6:127735361 T/C cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs7726839 0.540 rs7434 chr5:660804 A/G cg20362242 chr5:692897 TPPP -0.52 -4.92 -0.4 2.7e-6 Obesity-related traits; TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg04025307 chr7:1156635 C7orf50 0.22 5.23 0.43 6.97e-7 Longevity;Endometriosis; TGCT cis rs1949733 1.000 rs1949733 chr4:8503359 C/T cg11789530 chr4:8429930 ACOX3 -0.63 -5.8 -0.46 5.2e-8 Response to antineoplastic agents; TGCT cis rs9611565 0.592 rs9611612 chr22:41961189 T/C cg03806693 chr22:41940476 POLR3H -1.07 -11.34 -0.71 7.07e-21 Vitiligo; TGCT cis rs9467773 0.935 rs4573 chr6:26546808 A/G cg15659132 chr6:26577336 NA 0.81 10.65 0.69 3.23e-19 Intelligence (multi-trait analysis); TGCT cis rs7822232 0.908 rs6558295 chr8:145139522 C/G cg06495924 chr8:145149574 CYC1 -1.04 -4.49 -0.37 1.6e-5 Blood metabolite levels; TGCT cis rs1371867 0.846 rs1692007 chr8:101268343 T/C cg00191853 chr8:101177733 SPAG1 0.23 4.8 0.4 4.44e-6 Atrioventricular conduction; TGCT cis rs6088580 0.634 rs6058051 chr20:33044862 G/A cg08999081 chr20:33150536 PIGU 0.29 5.6 0.45 1.31e-7 Glomerular filtration rate (creatinine); TGCT cis rs10791097 0.720 rs4936121 chr11:130733878 A/G cg12179176 chr11:130786555 SNX19 0.83 9.45 0.65 2.77e-16 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs910187 0.678 rs7352690 chr20:45815352 C/G cg27589058 chr20:45804311 EYA2 -0.34 -7.21 -0.54 4.78e-11 Migraine; TGCT cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs9486715 0.659 rs9399930 chr6:96854444 G/T cg06623918 chr6:96969491 KIAA0776 1.02 12.09 0.74 1.01e-22 Headache; TGCT cis rs4631830 1.000 rs4631830 chr10:51543344 C/T cg10326726 chr10:51549505 MSMB -0.24 -4.64 -0.38 8.63e-6 Prostate-specific antigen levels; TGCT cis rs62344088 0.590 rs73016637 chr5:172462 G/A cg10601043 chr5:1076365 SLC12A7 0.58 4.74 0.39 5.71e-6 Asthma (childhood onset); TGCT cis rs4285028 1.000 rs4285028 chr3:121660664 A/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.78 -6.63 -0.51 9.43e-10 Multiple sclerosis; TGCT cis rs4906332 0.966 rs12885786 chr14:103972503 C/T cg26031613 chr14:104095156 KLC1 -0.54 -4.66 -0.39 8.15e-6 Coronary artery disease; TGCT cis rs12681287 0.570 rs4961188 chr8:87383033 T/C cg27223183 chr8:87520930 FAM82B 0.89 6.61 0.51 1.04e-9 Caudate activity during reward; TGCT cis rs12257961 0.521 rs7899540 chr10:15382782 G/A cg10616319 chr10:15468812 NA 0.25 4.71 0.39 6.49e-6 Selective IgA deficiency; TGCT cis rs17030434 0.911 rs75822357 chr4:154738258 T/C cg14289246 chr4:154710475 SFRP2 -0.88 -7.02 -0.53 1.3100000000000001e-10 Electrocardiographic conduction measures; TGCT cis rs2956278 0.717 rs7973519 chr12:84684752 A/G cg25678815 chr12:85673915 ALX1 -0.51 -4.64 -0.38 8.9e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs7824557 0.527 rs2572376 chr8:11237756 C/A cg21775007 chr8:11205619 TDH -0.7 -6.8 -0.52 3.92e-10 Retinal vascular caliber; TGCT trans rs28735056 0.904 rs9967107 chr18:77633343 C/T cg05926928 chr17:57297772 GDPD1 0.65 6.81 0.52 3.65e-10 Schizophrenia; TGCT cis rs2070488 0.804 rs6764551 chr3:38460305 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.8 7.95 0.58 1e-12 Electrocardiographic conduction measures; TGCT cis rs7264396 0.561 rs66483315 chr20:34573575 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.27 -4.76 -0.39 5.19e-6 Total cholesterol levels; TGCT cis rs8002180 0.959 rs9590228 chr13:95923390 C/T cg24476569 chr13:95954382 ABCC4 0.41 5.07 0.41 1.42e-6 Blood metabolite levels; TGCT cis rs1008375 0.902 rs6844984 chr4:17651304 C/G cg10189774 chr4:17578691 LAP3 0.55 4.9 0.4 2.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg00684032 chr4:1343700 KIAA1530 0.22 4.88 0.4 3.21e-6 Obesity-related traits; TGCT cis rs5769707 0.967 rs739248 chr22:50025205 T/C cg20744362 chr22:50050164 C22orf34 0.27 4.57 0.38 1.18e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs651907 0.535 rs61396602 chr3:101509046 T/C cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg07424592 chr7:64974309 NA 1.27 7.86 0.58 1.61e-12 Diabetic kidney disease; TGCT cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12580194 0.593 rs60230359 chr12:55736550 T/C cg10672482 chr12:55725839 OR6C3 -0.51 -4.46 -0.37 1.79e-5 Cancer; TGCT cis rs7208859 0.673 rs11650305 chr17:29229361 A/C cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6701037 0.566 rs1883102 chr1:175136793 T/A cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs17152411 0.895 rs11245422 chr10:126588143 T/C cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs453301 0.686 rs4840389 chr8:8884503 G/C cg06636001 chr8:8085503 FLJ10661 -0.69 -5.67 -0.45 9.36e-8 Joint mobility (Beighton score); TGCT cis rs853679 0.517 rs9295759 chr6:28124469 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs59698941 0.527 rs1910075 chr5:132180089 A/T cg27099455 chr5:132201840 GDF9;UQCRQ 0.28 4.76 0.39 5.3e-6 Apolipoprotein A-IV levels; TGCT cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.88 8.56 0.61 3.63e-14 Intelligence (multi-trait analysis); TGCT cis rs9911578 1.000 rs1971659 chr17:57004787 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.967 rs4723338 chr7:1036241 A/G cg00431813 chr7:1051703 C7orf50 -0.2 -4.43 -0.37 2.01e-5 Longevity;Endometriosis; TGCT cis rs6752107 1.000 rs2289472 chr2:234182240 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.81 0.4 4.36e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs782590 0.837 rs782573 chr2:55912961 T/C cg18811423 chr2:55921094 PNPT1 0.7 7.83 0.58 1.88e-12 Metabolic syndrome; TGCT cis rs4919044 0.545 rs9420603 chr10:94777490 T/C cg05127821 chr10:94822908 CYP26C1 -0.77 -5.03 -0.41 1.71e-6 Coronary artery disease; TGCT cis rs231513 0.681 rs8079623 chr17:42027330 C/G cg26893861 chr17:41843967 DUSP3 -0.69 -4.59 -0.38 1.08e-5 Cognitive function; TGCT cis rs9916302 0.706 rs8075737 chr17:37727316 C/T cg03321784 chr17:37729644 NA -0.44 -4.95 -0.41 2.4e-6 Glomerular filtration rate (creatinine); TGCT cis rs6688613 1.000 rs7533688 chr1:166944123 G/A cg07049167 chr1:166818506 POGK 0.22 4.55 0.38 1.25e-5 Refractive astigmatism; TGCT cis rs7193541 0.684 rs7201320 chr16:74694058 T/G cg01733217 chr16:74700730 RFWD3 0.99 13.35 0.77 9.31e-26 Multiple myeloma; TGCT cis rs79349575 0.783 rs4794000 chr17:47022755 C/G cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs829883 0.664 rs829864 chr12:98850195 C/T cg25150519 chr12:98850993 NA 0.64 7.54 0.56 8.56e-12 Colorectal adenoma (advanced); TGCT cis rs896854 0.818 rs13262110 chr8:95926890 C/T cg09323728 chr8:95962352 TP53INP1 -0.5 -6.36 -0.5 3.51e-9 Type 2 diabetes; TGCT cis rs7843479 1.000 rs7843479 chr8:21820813 G/T cg17168535 chr8:21777572 XPO7 0.62 5.49 0.44 2.13e-7 Mean corpuscular volume; TGCT cis rs9388451 0.591 rs1268792 chr6:126042124 G/A cg05901451 chr6:126070800 HEY2 0.89 8.8 0.62 9.88e-15 Brugada syndrome; TGCT cis rs12681288 0.676 rs17740799 chr8:1014327 C/T cg04851639 chr8:1020857 NA 0.36 6.82 0.52 3.62e-10 Schizophrenia; TGCT cis rs17221829 0.932 rs4753236 chr11:89448147 C/T cg02982614 chr11:89391479 FOLH1B -0.29 -5.09 -0.42 1.3e-6 Anxiety in major depressive disorder; TGCT cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs1153858 0.943 rs67045941 chr15:45677011 A/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7654585 0.782 rs2309288 chr4:25947097 C/A cg10409131 chr4:25915609 C4orf52 0.75 7.81 0.57 2.06e-12 Obesity-related traits; TGCT cis rs35160687 0.901 rs12620833 chr2:86472870 T/C cg04877910 chr2:85804641 VAMP8 0.35 4.6 0.38 1.04e-5 Night sleep phenotypes; TGCT cis rs28595532 0.920 rs115103359 chr4:119739608 A/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2072499 0.966 rs2842864 chr1:156159217 G/A cg24450063 chr1:156163899 SLC25A44 1.19 17.21 0.84 1.15e-34 Testicular germ cell tumor; TGCT cis rs9858542 0.953 rs6997 chr3:49453834 C/T cg03060546 chr3:49711283 APEH -0.64 -5.55 -0.45 1.64e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs10197940 0.638 rs2288193 chr2:152348842 T/A cg19508488 chr2:152266495 RIF1 0.73 6.69 0.51 6.91e-10 Lung cancer; TGCT cis rs3749237 0.964 rs2234385 chr3:49846041 G/A cg10152585 chr3:50297680 NA 0.51 4.84 0.4 3.79e-6 Resting heart rate; TGCT cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT trans rs4332037 0.575 rs55952733 chr7:2070680 G/A cg10840412 chr1:235813424 GNG4 0.95 6.94 0.53 1.97e-10 Bipolar disorder; TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT trans rs3107575 0.572 rs73169365 chr3:165319778 T/C cg20820622 chr15:70354647 TLE3 0.97 6.63 0.51 9.3e-10 Morning vs. evening chronotype; TGCT cis rs12681288 0.862 rs7015529 chr8:1020249 A/G cg21347738 chr8:1310380 NA -0.22 -4.57 -0.38 1.14e-5 Schizophrenia; TGCT cis rs910316 0.934 rs7141705 chr14:75655352 G/C cg08847533 chr14:75593920 NEK9 -0.91 -9.71 -0.66 6.33e-17 Height; TGCT cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.91 0.4 2.83e-6 Height; TGCT cis rs875971 0.660 rs6460308 chr7:66084740 T/C cg00343986 chr7:65444356 GUSB -0.23 -5.15 -0.42 9.77e-7 Aortic root size; TGCT cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg03806693 chr22:41940476 POLR3H -1.11 -12.05 -0.73 1.3e-22 Vitiligo; TGCT cis rs7772486 0.875 rs1331637 chr6:146337087 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.56 -0.38 1.23e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs11874712 0.932 rs34907121 chr18:43677793 G/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.04e-7 Migraine - clinic-based; TGCT cis rs9814567 1.000 rs9829092 chr3:134229866 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.12 16.7 0.83 1.62e-33 Prudent dietary pattern; TGCT cis rs4851254 0.618 rs4851243 chr2:100639482 G/A cg07810366 chr2:100720526 AFF3 -0.46 -4.64 -0.38 8.78e-6 Intelligence (multi-trait analysis); TGCT cis rs8078723 0.714 rs3859187 chr17:38150613 C/A cg17467752 chr17:38218738 THRA -0.53 -5.36 -0.43 3.83e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs11195062 0.693 rs11195033 chr10:111980235 A/G cg00817464 chr10:111662876 XPNPEP1 -0.26 -4.44 -0.37 2e-5 Multiple myeloma; TGCT cis rs12142240 0.698 rs13374893 chr1:46843800 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.51e-8 Menopause (age at onset); TGCT cis rs78487399 0.808 rs72865297 chr2:43743248 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.2 -0.42 8.11e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs797680 0.930 rs622608 chr1:93715219 G/A cg27528825 chr2:159282178 CCDC148 0.34 6.7 0.52 6.63e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10540 1.000 rs35231079 chr11:515224 G/A cg03934478 chr11:495069 RNH1 0.32 4.82 0.4 4.16e-6 Body mass index; TGCT cis rs9916302 0.904 rs34363096 chr17:37594294 G/A cg15445000 chr17:37608096 MED1 0.33 4.78 0.39 4.93e-6 Glomerular filtration rate (creatinine); TGCT cis rs514406 0.505 rs405208 chr1:53176674 C/T cg01802117 chr1:53393560 SCP2 -0.42 -4.88 -0.4 3.24e-6 Monocyte count; TGCT cis rs2016266 0.787 rs61928080 chr12:53752204 G/A cg16917193 chr12:54089295 NA -0.71 -4.6 -0.38 1.04e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs2797160 0.935 rs6940748 chr6:125994080 C/T cg05901451 chr6:126070800 HEY2 -0.74 -6.49 -0.5 1.84e-9 Endometrial cancer; TGCT cis rs11098499 1.000 rs12506395 chr4:120185094 C/T cg09307838 chr4:120376055 NA 0.49 4.52 0.38 1.43e-5 Corneal astigmatism; TGCT cis rs11711311 1.000 rs9865435 chr3:113450046 G/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs1865760 0.865 rs2164485 chr6:25952106 G/A cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs9303401 0.659 rs9303399 chr17:56672309 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.49 0.37 1.6e-5 Cognitive test performance; TGCT cis rs6570726 0.791 rs9403729 chr6:145907007 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.58 -0.38 1.13e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs113577745 0.725 rs73913928 chr2:10093003 G/A cg17603321 chr2:9696605 ADAM17 -1.15 -5.09 -0.42 1.31e-6 Breast cancer; TGCT cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs9303401 0.625 rs10515159 chr17:56802693 G/C cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg01341218 chr17:43662625 NA 1.11 9.15 0.63 1.43e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10791097 0.667 rs1893019 chr11:130756664 C/G cg14779329 chr11:130786720 SNX19 0.29 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2439831 0.867 rs2260160 chr15:43895643 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.57 0.45 1.49e-7 Lung cancer in ever smokers; TGCT cis rs2836974 0.932 rs8129416 chr21:40617145 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.65 0.65 9.11e-17 Cognitive function; TGCT cis rs10782582 0.586 rs1856791 chr1:76308942 C/T cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs35883536 0.647 rs945329 chr1:101084273 C/T cg06223162 chr1:101003688 GPR88 -0.42 -7.66 -0.57 4.51e-12 Monocyte count; TGCT cis rs7010267 0.602 rs4313185 chr8:120052549 G/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.62 0.38 9.52e-6 Total body bone mineral density (age 45-60); TGCT cis rs4851266 1.000 rs11686280 chr2:100827718 C/A cg22139774 chr2:100720529 AFF3 -0.36 -5.34 -0.43 4.23e-7 Educational attainment; TGCT trans rs1005277 0.579 rs2103938 chr10:38493998 T/G cg27523141 chr10:43048294 ZNF37B 0.71 8.17 0.59 3.03e-13 Extrinsic epigenetic age acceleration; TGCT trans rs11722228 0.549 rs56146302 chr4:10081052 C/T cg26043149 chr18:55253948 FECH 1.15 11.34 0.71 6.89e-21 Gout;Urate levels;Serum uric acid levels; TGCT cis rs12188164 0.762 rs11745923 chr5:475408 T/G cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.58 -0.38 1.13e-5 Cystic fibrosis severity; TGCT cis rs769267 0.930 rs1063966 chr19:19616742 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs9486719 0.522 rs4839683 chr6:96851933 A/G cg06623918 chr6:96969491 KIAA0776 0.87 6.99 0.53 1.52e-10 Migraine;Coronary artery disease; TGCT trans rs10504390 0.656 rs78310018 chr8:66486522 T/C cg18118147 chr19:51128640 SYT3 -0.77 -6.81 -0.52 3.71e-10 IgG glycosylation; TGCT cis rs6940638 0.956 rs12190473 chr6:27024687 C/T cg16898833 chr6:26189333 HIST1H4D 0.7 5.34 0.43 4.27e-7 Intelligence (multi-trait analysis); TGCT cis rs916888 0.773 rs199445 chr17:44817408 C/T cg16228356 chr17:43848958 NA -0.26 -4.53 -0.38 1.37e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7944584 0.545 rs7118178 chr11:47659135 G/A cg20307385 chr11:47447363 PSMC3 0.92 8.52 0.61 4.56e-14 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg13683864 chr3:40499215 RPL14 -1.14 -12.15 -0.74 7.25e-23 Renal cell carcinoma; TGCT cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg17054783 chr10:134559939 INPP5A 0.26 5.13 0.42 1.06e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.91 9.82 0.66 3.52e-17 Intelligence (multi-trait analysis); TGCT cis rs4234284 0.556 rs34147515 chr3:126965137 G/C cg26312807 chr3:127057048 NA -0.5 -4.57 -0.38 1.17e-5 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs4851254 0.584 rs56935201 chr2:100637788 G/A cg07810366 chr2:100720526 AFF3 -0.46 -4.64 -0.38 8.78e-6 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs613128 chr11:68638058 G/T cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7193541 0.585 rs3851729 chr16:74485529 A/G cg01733217 chr16:74700730 RFWD3 -0.82 -9.48 -0.65 2.24e-16 Multiple myeloma; TGCT cis rs1552244 0.554 rs6443275 chr3:10008819 G/A cg00149659 chr3:10157352 C3orf10 0.63 4.65 0.39 8.35e-6 Alzheimer's disease; TGCT cis rs62209 0.752 rs11256935 chr10:11004177 C/T cg26901096 chr10:10994189 LOC254312 0.4 6.3 0.49 4.64e-9 Alzheimer's disease (late onset); TGCT cis rs589448 0.967 rs2617835 chr12:69753420 C/A cg11871910 chr12:69753446 YEATS4 0.87 10.07 0.67 8.72e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs7267979 0.932 rs13040655 chr20:25582197 C/T cg03522245 chr20:25566470 NINL 0.6 6.12 0.48 1.11e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs4638749 1.000 rs2123694 chr2:108857505 A/G cg06795125 chr2:108905320 SULT1C2 -0.39 -4.81 -0.4 4.26e-6 Blood pressure; TGCT cis rs6988636 1.000 rs9987357 chr8:124187620 T/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg11905131 chr22:24372483 LOC391322 0.7 5.63 0.45 1.14e-7 S-phenylmercapturic acid levels in smokers; TGCT cis rs2153535 0.580 rs1119689 chr6:8460754 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9303401 0.659 rs1864754 chr17:56688789 G/T cg25039879 chr17:56429692 SUPT4H1 -0.51 -4.5 -0.37 1.54e-5 Cognitive test performance; TGCT cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs950027 0.584 rs1145086 chr15:45654327 A/G cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs17221829 0.965 rs1967075 chr11:89447256 A/G cg02982614 chr11:89391479 FOLH1B -0.29 -5.09 -0.42 1.3e-6 Anxiety in major depressive disorder; TGCT cis rs11249608 0.510 rs6861539 chr5:178452307 A/G cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs2235642 0.750 rs763152 chr16:1658056 T/C cg11375102 chr16:1583810 IFT140;TMEM204 -0.27 -4.66 -0.39 7.88e-6 Coronary artery disease; TGCT cis rs4727027 0.899 rs4727025 chr7:148862863 A/G cg23583168 chr7:148888333 NA -0.76 -10.09 -0.67 7.46e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs9354352 0.935 rs9354354 chr6:66699333 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.72 -7.84 -0.58 1.77e-12 Initial pursuit acceleration in psychotic disorders; TGCT cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg16049864 chr8:95962084 TP53INP1 -0.75 -10.47 -0.69 9.05e-19 Type 2 diabetes; TGCT cis rs4595586 0.615 rs11169838 chr12:39253108 C/T cg10518543 chr12:38710700 ALG10B -0.52 -4.48 -0.37 1.68e-5 Morning vs. evening chronotype; TGCT cis rs1915146 0.546 rs2454055 chr10:126859832 T/C cg23000734 chr10:126850823 CTBP2 0.48 5.21 0.42 7.76e-7 Menarche (age at onset); TGCT cis rs12579753 0.789 rs35448307 chr12:82165817 A/G cg21231944 chr12:82153410 PPFIA2 -0.34 -4.62 -0.38 9.52e-6 Resting heart rate; TGCT cis rs7258465 0.965 rs271628 chr19:18624333 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs10501293 0.662 rs7929773 chr11:42999551 C/G cg03447554 chr11:43094025 NA -0.44 -6.34 -0.49 3.9e-9 Cognitive performance; TGCT cis rs7678296 0.649 rs60691639 chr4:37239925 T/C cg18431856 chr4:37245254 KIAA1239 0.68 4.49 0.37 1.64e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs8038465 0.622 rs60696711 chr15:73873005 C/A cg15420318 chr15:73925796 NPTN 0.64 6.8 0.52 3.87e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2404602 0.716 rs1874944 chr15:76863928 A/G cg22467129 chr15:76604101 ETFA -0.44 -5.05 -0.41 1.51e-6 Blood metabolite levels; TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.77 -7.46 -0.56 1.33e-11 Prudent dietary pattern; TGCT cis rs2737273 1.000 rs2737273 chr9:35716066 T/C cg12717594 chr9:36037454 RECK 0.53 4.54 0.38 1.3e-5 Platelet distribution width; TGCT cis rs3734905 1.000 rs79846353 chr6:169894834 C/T cg20469989 chr6:170102314 C6orf120;WDR27 -0.88 -4.67 -0.39 7.59e-6 HIV-1 control; TGCT cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs12681287 0.640 rs13264364 chr8:87466385 G/T cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs7829975 0.510 rs332037 chr8:8722675 C/T cg15556689 chr8:8085844 FLJ10661 0.64 5.81 0.46 5.01e-8 Mood instability; TGCT cis rs6665290 0.669 rs3768419 chr1:227173477 C/G cg10327440 chr1:227177885 CDC42BPA -0.88 -14.6 -0.8 1.04e-28 Myeloid white cell count; TGCT cis rs909341 0.678 rs2738778 chr20:62291830 C/T cg14758556 chr20:62440591 NA 0.37 5.05 0.41 1.57e-6 Atopic dermatitis; TGCT trans rs4332037 0.851 rs1403175 chr7:1964357 A/T cg10840412 chr1:235813424 GNG4 -1.05 -8.44 -0.6 7.18e-14 Bipolar disorder; TGCT cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg06634786 chr22:41940651 POLR3H -0.72 -6.8 -0.52 3.99e-10 Vitiligo; TGCT cis rs6121246 0.647 rs6088855 chr20:30225792 C/T cg18721089 chr20:30220636 NA -0.57 -5.73 -0.46 7.05e-8 Mean corpuscular hemoglobin; TGCT cis rs875971 0.660 rs79009421 chr7:66068509 G/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs1975974 0.539 rs58796614 chr17:21733767 C/T cg18423549 chr17:21743878 NA -0.61 -5.99 -0.47 2.14e-8 Psoriasis; TGCT cis rs1903068 0.925 rs1551642 chr4:55994210 T/C cg16572876 chr4:56024045 NA 0.45 5.08 0.42 1.34e-6 Endometriosis; TGCT cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs9868809 0.505 rs73080312 chr3:48737847 C/T cg00383909 chr3:49044727 WDR6 1.54 5.91 0.47 3.14e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs4499344 0.730 rs2903755 chr19:33098870 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs10465746 0.967 rs12759527 chr1:84434425 T/C cg10977910 chr1:84465055 TTLL7 0.63 6.23 0.49 6.49e-9 Obesity-related traits; TGCT cis rs7100689 0.646 rs10736345 chr10:82134140 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs2455799 0.613 rs2470548 chr3:15737689 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.62 -0.38 9.34e-6 Mean platelet volume; TGCT cis rs4975709 0.589 rs931508 chr5:1861224 C/G cg14773178 chr5:1868261 NA 0.34 5.57 0.45 1.54e-7 Cardiovascular disease risk factors; TGCT cis rs2404602 0.583 rs35707798 chr15:76565026 G/C cg26408565 chr15:76604113 ETFA -0.45 -6.35 -0.5 3.66e-9 Blood metabolite levels; TGCT cis rs10479542 0.929 rs7718673 chr5:178980009 C/T cg19723775 chr5:179050963 HNRNPH1 -0.52 -5.13 -0.42 1.08e-6 Lung cancer; TGCT cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg09222892 chr1:25734099 RHCE 0.42 7.16 0.54 6.34e-11 Erythrocyte sedimentation rate; TGCT cis rs7772486 0.840 rs2814867 chr6:146334030 C/A cg23711669 chr6:146136114 FBXO30 0.87 9.3 0.64 6.21e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4076764 1.000 rs6683181 chr1:163417077 C/T cg24596788 chr1:163392923 NA -0.17 -4.81 -0.4 4.22e-6 Motion sickness; TGCT cis rs5769765 0.773 rs9616208 chr22:50313359 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -13.17 -0.76 2.52e-25 Schizophrenia; TGCT cis rs12188164 0.965 rs11743639 chr5:450710 C/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg03517284 chr6:25882590 NA -0.58 -6.03 -0.48 1.76e-8 Blood metabolite levels; TGCT cis rs7909074 1.000 rs1408814 chr10:45399088 A/G cg05187965 chr10:45406764 TMEM72 -0.25 -5.3 -0.43 5.07e-7 Mean corpuscular volume; TGCT cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg07507251 chr3:52567010 NT5DC2 0.49 7.07 0.54 1e-10 Bipolar disorder; TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs3947 0.789 rs6990033 chr8:11693378 G/T cg02840367 chr8:11660030 FDFT1 -0.94 -6.9 -0.53 2.43e-10 Blood protein levels; TGCT cis rs3849570 0.643 rs10779986 chr3:81970818 C/G cg07356753 chr3:81810745 GBE1 0.72 6.76 0.52 4.82e-10 Waist circumference;Body mass index; TGCT cis rs7246657 0.943 rs9917081 chr19:37876616 T/C cg18154014 chr19:37997991 ZNF793 1.0 6.69 0.52 6.81e-10 Coronary artery calcification; TGCT cis rs832540 0.898 rs331497 chr5:56251660 G/T cg24531977 chr5:56204891 C5orf35 0.49 5.21 0.42 7.8e-7 Coronary artery disease; TGCT cis rs727505 0.821 rs73225498 chr7:124704197 C/T cg23710748 chr7:124431027 NA -0.27 -4.59 -0.38 1.07e-5 Lewy body disease; TGCT cis rs2224391 0.628 rs2753234 chr6:5251050 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs920590 0.500 rs7819535 chr8:19689058 A/G cg03894339 chr8:19674705 INTS10 0.99 6.24 0.49 6.4e-9 Acute lymphoblastic leukemia (childhood); TGCT cis rs7829975 0.511 rs2921028 chr8:8340477 T/C cg15556689 chr8:8085844 FLJ10661 0.66 6.39 0.5 2.98e-9 Mood instability; TGCT cis rs13188771 0.690 rs164622 chr5:100874123 C/G cg18665594 chr5:101119420 NA 0.44 4.46 0.37 1.83e-5 Conduct disorder (maternal expressed emotions interaction); TGCT trans rs7618501 0.602 rs9311446 chr3:50092226 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs3087591 0.960 rs2905872 chr17:29525027 C/A cg24425628 chr17:29625626 OMG;NF1 0.48 7.29 0.55 3.25e-11 Hip circumference; TGCT cis rs765787 0.530 rs4775837 chr15:45537684 G/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7772486 0.764 rs2265471 chr6:146220250 G/A cg23711669 chr6:146136114 FBXO30 0.89 10.16 0.67 5.28e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.962 rs1527515 chr4:99025733 C/A cg05340658 chr4:99064831 C4orf37 0.46 4.57 0.38 1.18e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs10114408 0.959 rs11792740 chr9:96653951 C/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs763014 0.966 rs4247097 chr16:654224 G/A cg27436995 chr16:743998 FBXL16 -0.47 -5.13 -0.42 1.07e-6 Height; TGCT cis rs9911578 1.000 rs304292 chr17:56824123 G/A cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.623 rs11652358 chr17:29205480 T/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9381040 0.610 rs2235678 chr6:41020510 G/T cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT trans rs7618501 0.602 rs6780731 chr3:50017478 A/G cg21659725 chr3:3221576 CRBN 0.77 9.27 0.64 7.26e-16 Intelligence (multi-trait analysis); TGCT cis rs6460942 0.915 rs75732743 chr7:12454095 C/T cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT trans rs114540395 0.858 rs74415794 chr10:103238858 A/G cg10198749 chr1:39920707 MACF1 0.55 7.12 0.54 7.73e-11 Schizophrenia; TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg05215272 chr17:6899095 ALOX12 0.54 6.63 0.51 9.29e-10 Tonsillectomy; TGCT cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg12310025 chr6:25882481 NA -0.59 -6.04 -0.48 1.65e-8 Blood metabolite levels; TGCT cis rs1941184 0.500 rs7234091 chr18:29019829 C/T cg14871544 chr18:29027885 DSG3 0.44 4.63 0.38 9.18e-6 Parkinson's disease (age of onset); TGCT cis rs910316 1.000 rs12889309 chr14:75593902 C/T cg23033748 chr14:75592666 NEK9 0.28 4.79 0.39 4.73e-6 Height; TGCT cis rs4951018 0.821 rs11240547 chr1:205632932 A/G cg24503407 chr1:205819492 PM20D1 0.38 4.82 0.4 4.05e-6 Prostate-specific antigen levels; TGCT cis rs17473412 0.677 rs7703751 chr5:122831981 A/T cg15125798 chr5:122621645 NA -0.57 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT cis rs2239785 0.883 rs136157 chr22:36656443 C/A cg15716373 chr22:36655542 APOL1 -0.41 -4.94 -0.41 2.44e-6 Glomerulosclerosis; TGCT cis rs62380364 0.626 rs618741 chr5:88064012 C/T cg22951263 chr5:87985283 NA -0.59 -6.27 -0.49 5.5e-9 Intelligence (multi-trait analysis); TGCT cis rs988712 0.705 rs35051342 chr11:27634373 G/C cg10635145 chr11:27742435 BDNF -0.38 -5.25 -0.43 6.38e-7 Obesity; TGCT cis rs2147959 0.824 rs10799479 chr1:228678510 G/A cg22700015 chr1:228743131 NA -0.63 -4.82 -0.4 4.2e-6 Adult asthma; TGCT cis rs6901004 0.803 rs9320360 chr6:111462272 G/T cg15721981 chr6:111408429 SLC16A10 -0.53 -4.64 -0.38 8.82e-6 Blood metabolite levels; TGCT cis rs60843830 0.928 rs2306060 chr2:230912 A/C cg25945732 chr2:264204 ACP1;SH3YL1 0.79 8.04 0.59 5.94e-13 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs73252553 0.547 rs315683 chr4:25375455 C/G cg04009456 chr4:25379436 ANAPC4 0.4 4.46 0.37 1.84e-5 Cannabis dependence symptom count; TGCT cis rs4927850 1.000 rs7630875 chr3:195753766 A/G cg12923728 chr3:195709715 SDHAP1 -0.36 -7.43 -0.55 1.56e-11 Pancreatic cancer; TGCT cis rs7666738 0.830 rs732299 chr4:98995389 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.6 0.45 1.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.777 rs114096617 chr12:38342557 A/C cg26384229 chr12:38710491 ALG10B 0.82 7.22 0.54 4.5e-11 Bladder cancer; TGCT cis rs826838 1.000 rs11610522 chr12:38687575 C/T cg13010199 chr12:38710504 ALG10B 0.82 6.65 0.51 8.46e-10 Heart rate; TGCT cis rs2658782 1.000 rs2658781 chr11:93166368 C/T cg15737290 chr11:93063684 CCDC67 -0.74 -5.71 -0.46 7.94e-8 Pulmonary function decline; TGCT cis rs6540559 1.000 rs1044516 chr1:209959614 G/T cg23283495 chr1:209979779 IRF6 0.67 5.64 0.45 1.08e-7 Cleft lip with or without cleft palate; TGCT cis rs17376456 0.877 rs34673483 chr5:93315079 C/A cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs3960554 0.529 rs7800970 chr7:75880198 C/T cg19105122 chr7:75896889 SRRM3 -0.58 -4.91 -0.4 2.85e-6 Eotaxin levels; TGCT cis rs28595532 0.764 rs116788606 chr4:119748849 G/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7914558 0.966 rs12569617 chr10:104729996 T/C cg05855489 chr10:104503620 C10orf26 0.51 4.53 0.38 1.37e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1552244 0.554 rs34391585 chr3:9999208 G/C cg00149659 chr3:10157352 C3orf10 0.65 4.8 0.4 4.49e-6 Alzheimer's disease; TGCT cis rs651907 0.535 rs2290859 chr3:101525625 C/T cg12386194 chr3:101231763 SENP7 0.48 4.65 0.39 8.26e-6 Colorectal cancer; TGCT cis rs4927850 0.723 rs7630825 chr3:195753740 T/C cg22891161 chr3:195456627 MUC20 -0.21 -4.48 -0.37 1.7e-5 Pancreatic cancer; TGCT cis rs4727027 0.804 rs13231262 chr7:148886058 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.75 0.39 5.54e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4851266 1.000 rs11693324 chr2:100827753 T/C cg22139774 chr2:100720529 AFF3 -0.35 -5.31 -0.43 4.92e-7 Educational attainment; TGCT trans rs4332037 0.851 rs73050128 chr7:1961882 C/A cg25206134 chr2:45395956 NA 1.1 9.53 0.65 1.75e-16 Bipolar disorder; TGCT cis rs992157 0.710 rs6752254 chr2:219058743 C/T cg00012203 chr2:219082015 ARPC2 0.83 10.62 0.69 4.01e-19 Colorectal cancer; TGCT cis rs11585357 0.793 rs112597506 chr1:17628832 A/G cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 7.0 0.53 1.44e-10 Platelet count; TGCT cis rs367943 0.966 rs364738 chr5:112808329 A/G cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs10791323 0.572 rs4353292 chr11:133742656 A/G cg03690763 chr11:133734501 NA -0.29 -4.98 -0.41 2.09e-6 Childhood ear infection; TGCT cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs524281 1.000 rs547087 chr11:65846264 A/G cg00563793 chr11:65837595 PACS1 -0.52 -4.46 -0.37 1.82e-5 Electroencephalogram traits; TGCT cis rs1981331 1.000 rs77587985 chr21:47993897 A/G cg23283320 chr21:48055893 PRMT2 1.29 6.09 0.48 1.31e-8 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT trans rs10435719 0.809 rs77601743 chr8:11790569 G/A cg15556689 chr8:8085844 FLJ10661 0.76 7.18 0.54 5.62e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs7267979 1.000 rs2259928 chr20:25281834 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs35306767 0.953 rs1539174 chr10:974870 C/G cg26597838 chr10:835615 NA 0.56 7.7 0.57 3.77e-12 Eosinophil percentage of granulocytes; TGCT cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg03806693 chr22:41940476 POLR3H 1.08 11.99 0.73 1.84e-22 Vitiligo; TGCT cis rs10992471 0.603 rs10992349 chr9:95233887 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.79 -0.46 5.39e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6684514 0.845 rs12138564 chr1:156291600 G/T cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs289997 0.920 rs2999569 chr7:25582362 A/G cg14064488 chr7:26331273 SNX10 0.34 4.93 0.4 2.57e-6 Breast cancer; TGCT trans rs77457752 0.690 rs12349345 chr9:13912075 T/C cg18948646 chr4:83674694 SCD5;MIR575 0.55 6.62 0.51 9.75e-10 Breast cancer; TGCT cis rs13191362 1.000 rs35449999 chr6:163023465 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg09222892 chr1:25734099 RHCE -0.45 -7.33 -0.55 2.63e-11 Erythrocyte sedimentation rate; TGCT cis rs60843830 1.000 rs3828165 chr2:220889 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.74 6.76 0.52 4.93e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7296418 0.885 rs1716184 chr12:123637509 G/C cg05973401 chr12:123451056 ABCB9 0.54 4.47 0.37 1.71e-5 Platelet count; TGCT cis rs939658 0.805 rs34478496 chr15:79440997 C/A cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs8038465 0.874 rs11574495 chr15:74003936 C/T cg15420318 chr15:73925796 NPTN 0.53 4.89 0.4 3.1e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7226408 0.948 rs11662148 chr18:34408423 A/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs9916302 0.904 rs8065879 chr17:37515978 G/A cg07936489 chr17:37558343 FBXL20 0.65 5.09 0.42 1.3e-6 Glomerular filtration rate (creatinine); TGCT cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg03264133 chr6:25882463 NA -0.57 -6.07 -0.48 1.45e-8 Blood metabolite levels; TGCT cis rs8013055 0.846 rs10152050 chr14:105984145 C/G cg23356831 chr14:105996513 TMEM121 0.33 4.83 0.4 3.86e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7220711 0.934 rs7217502 chr17:41801246 A/C cg26893861 chr17:41843967 DUSP3 0.55 4.98 0.41 2.09e-6 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs986417 0.892 rs11628559 chr14:61038153 G/C cg27398547 chr14:60952738 C14orf39 1.55 8.76 0.62 1.22e-14 Gut microbiota (bacterial taxa); TGCT cis rs478304 0.654 rs12289836 chr11:65436888 C/T cg17480646 chr11:65405466 SIPA1 0.62 8.19 0.59 2.69e-13 Acne (severe); TGCT cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg13683864 chr3:40499215 RPL14 -1.17 -13.15 -0.76 2.93e-25 Renal cell carcinoma; TGCT cis rs6912958 0.754 rs6918909 chr6:88247251 A/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.92 -0.4 2.7e-6 Monocyte percentage of white cells; TGCT cis rs968451 0.619 rs2267407 chr22:39747050 G/A cg17798944 chr22:39715225 SNORD43;RPL3 0.76 6.89 0.53 2.47e-10 Primary biliary cholangitis; TGCT cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Vitiligo; TGCT cis rs7949030 0.591 rs11231156 chr11:62366454 G/A cg11742103 chr11:62369870 EML3;MTA2 0.61 8.75 0.62 1.29e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1336900 0.513 rs56253522 chr1:150614869 C/A cg04414720 chr1:150670196 GOLPH3L 0.39 4.84 0.4 3.74e-6 Blood protein levels; TGCT cis rs137603 0.644 rs137636 chr22:39722477 C/A cg01093212 chr22:39715156 SNORD43;RPL3 -0.53 -5.16 -0.42 9.64e-7 Primary biliary cholangitis; TGCT cis rs7523273 0.565 rs2761422 chr1:207893266 A/T cg22525895 chr1:207977042 MIR29B2 0.34 5.76 0.46 6.15e-8 Schizophrenia; TGCT trans rs7618501 0.633 rs11130228 chr3:50003246 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.87 9.66 0.66 8.25e-17 Intelligence (multi-trait analysis); TGCT cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg23205692 chr1:25664452 TMEM50A 0.5 5.21 0.42 7.72e-7 Erythrocyte sedimentation rate; TGCT cis rs9467711 0.790 rs35162296 chr6:26318262 C/T cg16898833 chr6:26189333 HIST1H4D 1.2 5.52 0.44 1.87e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.546 rs10010088 chr4:98655945 C/T cg17366294 chr4:99064904 C4orf37 0.58 5.36 0.43 3.87e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9486715 0.867 rs9486444 chr6:96963619 A/G cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs8077577 0.895 rs16960990 chr17:18108601 A/G cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs62064224 0.658 rs62065460 chr17:30715007 A/G cg18200150 chr17:30822561 MYO1D 0.58 7.69 0.57 3.92e-12 Schizophrenia; TGCT cis rs9372498 0.536 rs9489458 chr6:118920503 G/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.13 -0.42 1.07e-6 Diastolic blood pressure; TGCT cis rs9972944 0.756 rs7207587 chr17:63766307 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs7208859 0.623 rs11657391 chr17:29194287 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12049351 0.774 rs4925457 chr1:229633571 C/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs17331151 0.505 rs13086936 chr3:52659079 T/C cg07884673 chr3:53033167 SFMBT1 0.75 5.59 0.45 1.35e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8084125 0.832 rs2156646 chr18:74946660 C/T cg05528293 chr18:74961138 GALR1 0.5 4.88 0.4 3.17e-6 Obesity-related traits; TGCT cis rs13177918 0.626 rs13175436 chr5:149830537 A/T cg14059543 chr5:149831962 NA -0.68 -9.13 -0.63 1.6e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12681287 0.547 rs7461366 chr8:87511685 C/T cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs1163251 0.837 rs2764886 chr1:120241771 C/T cg19096424 chr1:120255104 PHGDH 0.6 5.94 0.47 2.66e-8 Blood metabolite levels; TGCT cis rs6570726 0.791 rs447992 chr6:145817184 C/T cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11696501 0.688 rs11696685 chr20:44295134 A/G cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs12579753 0.956 rs11115038 chr12:82214660 T/G cg07988820 chr12:82153109 PPFIA2 -0.64 -6.68 -0.51 7.15e-10 Resting heart rate; TGCT cis rs116095464 0.558 rs7725227 chr5:233517 G/A cg22857025 chr5:266934 NA -0.34 -6.64 -0.51 8.6e-10 Breast cancer; TGCT cis rs7666738 0.830 rs2019163 chr4:99022747 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.54 0.45 1.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.966 rs2482948 chr20:25296499 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 0.528 rs2387976 chr20:25599560 C/T cg03522245 chr20:25566470 NINL -0.45 -4.69 -0.39 6.99e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6490294 0.561 rs10744777 chr12:112233018 C/T cg10833066 chr12:111807467 FAM109A -0.29 -4.84 -0.4 3.85e-6 Mean platelet volume; TGCT cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg09323728 chr8:95962352 TP53INP1 -0.42 -5.01 -0.41 1.83e-6 Type 2 diabetes; TGCT cis rs35306767 0.807 rs61831436 chr10:837882 G/A cg20503657 chr10:835505 NA 0.78 11.16 0.71 1.88e-20 Eosinophil percentage of granulocytes; TGCT cis rs2153535 0.580 rs6941670 chr6:8446346 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.65 0.45 1.02e-7 Motion sickness; TGCT cis rs8177253 1.000 rs1525892 chr3:133484712 C/T cg20276088 chr3:133502917 NA -0.24 -5.17 -0.42 9.11e-7 Iron status biomarkers; TGCT cis rs3020333 0.653 rs851984 chr6:152023191 G/A cg22157087 chr6:152012887 ESR1 0.25 6.03 0.48 1.76e-8 Total body bone mineral density; TGCT cis rs6700896 0.522 rs12042379 chr1:66158464 G/T cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4665809 1.000 rs17040322 chr2:26351274 G/C cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs2228479 0.867 rs2270459 chr16:89979851 A/C cg06558623 chr16:89946397 TCF25 -0.55 -7.35 -0.55 2.28e-11 Skin colour saturation; TGCT cis rs3734729 1.000 rs3734730 chr6:150570940 T/C cg16439130 chr6:149658548 MAP3K7IP2 0.52 4.96 0.41 2.25e-6 Pulmonary function;Pulmonary function (smoking interaction); TGCT cis rs2836950 0.545 rs1888489 chr21:40533164 T/C cg11890956 chr21:40555474 PSMG1 -0.7 -6.8 -0.52 3.87e-10 Menarche (age at onset); TGCT cis rs2688608 0.592 rs11000757 chr10:75486815 T/C cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs2742417 0.967 rs9877499 chr3:45734404 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.07e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7666738 0.830 rs1349757 chr4:99058763 C/G cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.9e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.515 rs28853661 chr3:10177659 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.35 -4.75 -0.39 5.62e-6 Alzheimer's disease; TGCT cis rs7824557 0.518 rs11777007 chr8:10801857 C/T cg27411982 chr8:10470053 RP1L1 -0.24 -5.04 -0.41 1.62e-6 Retinal vascular caliber; TGCT cis rs11190604 0.767 rs10786590 chr10:102164604 T/C cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7824557 0.767 rs2060463 chr8:11161610 T/G cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs4494114 0.875 rs7518432 chr1:39363522 G/C cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.18e-9 Blood protein levels; TGCT cis rs4242434 0.892 rs34269854 chr8:22465160 G/C cg03733263 chr8:22462867 KIAA1967 1.14 20.09 0.87 8.18e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs10838634 1.000 rs12287376 chr11:46857059 C/T cg18332754 chr11:46939436 LRP4 0.9 4.58 0.38 1.11e-5 Schizophrenia; TGCT trans rs6089829 0.962 rs6089826 chr20:61668595 G/A cg13615516 chr5:77269221 NA 0.72 9.08 0.63 2.05e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs11122272 0.668 rs2790874 chr1:231537988 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs908922 0.676 rs7545336 chr1:152527863 A/G cg20991723 chr1:152506922 NA 0.45 6.06 0.48 1.55e-8 Hair morphology; TGCT cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg06634786 chr22:41940651 POLR3H 0.89 8.81 0.62 9.46e-15 Vitiligo; TGCT cis rs55962025 1.000 rs2285087 chr4:3088211 A/G cg06533319 chr4:3265114 C4orf44 0.22 4.66 0.39 8.19e-6 Parental longevity (mother's age at death); TGCT cis rs7666738 0.645 rs10013290 chr4:99082799 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.64 0.45 1.08e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs1115079 chr6:8449615 G/C cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg12667521 chr19:29218732 NA 0.51 6.05 0.48 1.57e-8 Methadone dose in opioid dependence; TGCT cis rs3902035 0.964 rs28710027 chr6:119009295 G/A cg07617317 chr6:118971624 C6orf204 0.42 5.08 0.42 1.35e-6 QT interval; TGCT cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs7647973 0.677 rs11130211 chr3:49645209 C/T cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs6964587 0.869 rs11769294 chr7:91549937 C/T cg17063962 chr7:91808500 NA 0.73 5.62 0.45 1.19e-7 Breast cancer; TGCT cis rs11650494 0.901 rs117087923 chr17:47364913 G/A cg08112188 chr17:47440006 ZNF652 1.05 5.4 0.44 3.32e-7 Prostate cancer; TGCT cis rs4654899 0.931 rs4654880 chr1:21186608 C/A cg01072550 chr1:21505969 NA 0.5 7.93 0.58 1.08e-12 Superior frontal gyrus grey matter volume; TGCT cis rs62244186 0.516 rs11922470 chr3:44777795 C/T cg15687855 chr3:44754131 ZNF502 -0.42 -4.68 -0.39 7.42e-6 Depressive symptoms; TGCT cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg22121687 chr7:65037720 NA -0.76 -4.45 -0.37 1.87e-5 Diabetic kidney disease; TGCT cis rs4727027 0.933 rs2158633 chr7:148832652 C/T cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6939532 0.544 rs10946816 chr6:26361946 C/G cg05738196 chr6:26577821 NA -0.53 -5.03 -0.41 1.68e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9796 0.870 rs7169375 chr15:41311046 A/G cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.41 -0.44 3.06e-7 Menopause (age at onset); TGCT cis rs7809950 1.000 rs2520249 chr7:107146748 A/G cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs72949976 0.864 rs10176806 chr2:214022596 T/G cg08319019 chr2:214017104 IKZF2 -0.76 -7.04 -0.53 1.14e-10 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs7010267 0.596 rs1905778 chr8:120021848 A/C cg17171407 chr8:119960777 TNFRSF11B 0.25 4.45 0.37 1.87e-5 Total body bone mineral density (age 45-60); TGCT cis rs7617773 0.563 rs62263035 chr3:48391569 C/T cg11946769 chr3:48343235 NME6 0.57 4.89 0.4 3.05e-6 Coronary artery disease; TGCT cis rs7568458 0.837 rs3731827 chr2:85806068 T/C cg02493740 chr2:85810744 VAMP5 -0.27 -4.85 -0.4 3.63e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs422249 0.512 rs174578 chr11:61605499 T/A cg19610905 chr11:61596333 FADS2 -0.95 -9.31 -0.64 6.01e-16 Trans fatty acid levels; TGCT cis rs72781680 0.821 rs2339887 chr2:24198376 G/A cg08917208 chr2:24149416 ATAD2B 0.72 4.5 0.37 1.56e-5 Lymphocyte counts; TGCT cis rs1005277 0.522 rs1208681 chr10:38092975 C/T cg25427524 chr10:38739819 LOC399744 -0.32 -6.45 -0.5 2.22e-9 Extrinsic epigenetic age acceleration; TGCT cis rs35146811 0.735 rs6948729 chr7:99787372 A/G cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs9911578 1.000 rs12947785 chr17:57045160 A/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs362272 0.505 rs3129310 chr4:3301388 T/G cg18352616 chr4:3374830 RGS12 0.24 4.7 0.39 6.93e-6 Serum sulfate level; TGCT cis rs939658 0.875 rs2177057 chr15:79441441 G/C cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs9911578 1.000 rs304299 chr17:56838472 C/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs13147768 chr4:98833675 A/T cg05340658 chr4:99064831 C4orf37 0.53 6.18 0.49 8.5e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs739496 0.615 rs56884502 chr12:112207300 T/A cg10833066 chr12:111807467 FAM109A 0.36 4.67 0.39 7.74e-6 Platelet count; TGCT cis rs3796352 1.000 rs11714876 chr3:53101640 C/G cg15956490 chr3:53032818 SFMBT1 -0.59 -6.67 -0.51 7.64e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3749237 0.615 rs55957735 chr3:49438158 G/A cg02487422 chr3:49467188 NICN1 0.59 6.01 0.47 1.92e-8 Resting heart rate; TGCT cis rs644799 1.000 rs494829 chr11:95571750 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 9.73 0.66 5.62e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9527 0.615 rs4917991 chr10:104783833 T/C cg15744005 chr10:104629667 AS3MT -0.42 -4.92 -0.4 2.74e-6 Arsenic metabolism; TGCT cis rs13064411 0.696 rs6798938 chr3:113218206 C/T cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9393692 0.840 rs9358915 chr6:26277268 G/A cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT trans rs57221529 0.766 rs72706608 chr5:559203 C/T cg11887960 chr12:57824829 NA 1.15 9.35 0.64 4.71e-16 Lung disease severity in cystic fibrosis; TGCT cis rs12477438 0.798 rs7606635 chr2:99644782 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs6430585 0.528 rs56064699 chr2:136595706 G/A cg07169764 chr2:136633963 MCM6 1.21 11.6 0.72 1.59e-21 Corneal structure; TGCT cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg22105103 chr4:187893119 NA 0.35 4.89 0.4 3.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6460942 0.915 rs17324858 chr7:12305792 G/T cg06484146 chr7:12443880 VWDE -0.43 -4.58 -0.38 1.12e-5 Coronary artery disease; TGCT cis rs9640161 0.789 rs60283368 chr7:150023258 G/A cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 9.08e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs12210905 0.688 rs12212389 chr6:27326397 T/C cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs7617773 0.539 rs35460860 chr3:48392085 A/T cg11946769 chr3:48343235 NME6 0.59 4.91 0.4 2.83e-6 Coronary artery disease; TGCT cis rs2657888 0.529 rs34287864 chr12:56858317 G/A cg23002907 chr12:56915593 RBMS2 -0.45 -5.72 -0.46 7.37e-8 Adiponectin levels; TGCT cis rs9372498 0.536 rs62663261 chr6:118900553 T/C cg21191810 chr6:118973309 C6orf204 -0.39 -5.06 -0.41 1.5e-6 Diastolic blood pressure; TGCT cis rs2204008 0.837 rs11169157 chr12:37980047 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.56e-12 Bladder cancer; TGCT cis rs1577917 1.000 rs2816821 chr6:86657084 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs941873 0.900 rs4979862 chr10:81131599 G/A cg09469691 chr10:81107165 PPIF 0.66 6.87 0.53 2.75e-10 Height; TGCT cis rs6500602 0.627 rs860891 chr16:4586529 C/T cg08645402 chr16:4508243 NA -0.21 -5.47 -0.44 2.4e-7 Schizophrenia; TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg01802117 chr1:53393560 SCP2 -0.39 -4.61 -0.38 1e-5 Monocyte count; TGCT cis rs9457247 1.000 rs439553 chr6:167391212 A/G cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs3858526 0.916 rs11039551 chr11:5930773 C/T cg05234568 chr11:5960015 NA -0.44 -4.6 -0.38 1.03e-5 DNA methylation (variation); TGCT cis rs6087990 0.765 rs6058900 chr20:31400673 T/C cg13636640 chr20:31349939 DNMT3B 0.96 11.62 0.72 1.4e-21 Ulcerative colitis; TGCT cis rs2839186 0.588 rs2839140 chr21:47616080 G/A cg05896524 chr21:47604654 C21orf56 -0.43 -4.54 -0.38 1.31e-5 Testicular germ cell tumor; TGCT cis rs7781977 0.575 rs7782210 chr7:50348745 A/G cg14216940 chr7:50343131 IKZF1 0.37 4.65 0.39 8.31e-6 IgG glycosylation; TGCT cis rs9894429 0.671 rs6565616 chr17:79612161 C/T cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs16867321 0.507 rs2013577 chr2:181370505 C/T cg23363182 chr2:181467187 NA -0.33 -4.98 -0.41 2.05e-6 Obesity; TGCT cis rs7819412 0.838 rs3021494 chr8:10983534 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.6 -0.38 1.02e-5 Triglycerides; TGCT cis rs7208859 0.623 rs216436 chr17:28922900 G/A cg14008862 chr17:28927542 LRRC37B2 0.93 5.64 0.45 1.11e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg23719950 chr11:63933701 MACROD1 -0.71 -5.91 -0.47 3.06e-8 Mean platelet volume; TGCT cis rs3748682 0.861 rs72661832 chr1:38260733 C/T cg04496824 chr1:38276835 MTF1 0.21 4.63 0.38 9.22e-6 Hypothyroidism; TGCT cis rs2463822 1.000 rs2463822 chr11:62103420 T/C cg06239285 chr11:62104954 ASRGL1 0.95 6.56 0.51 1.33e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9399135 0.967 rs6923827 chr6:135335382 C/T cg24558204 chr6:135376177 HBS1L 0.46 4.59 0.38 1.09e-5 Red blood cell count; TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg02073558 chr3:44770973 ZNF501 0.58 5.57 0.45 1.5e-7 Depressive symptoms; TGCT cis rs1670533 1.000 rs3816474 chr4:1050653 G/A cg27284194 chr4:1044797 NA 0.63 4.9 0.4 2.87e-6 Recombination rate (females); TGCT cis rs1059312 1.000 rs7136092 chr12:129280164 G/C cg09035930 chr12:129282057 SLC15A4 0.59 11.76 0.73 6.45e-22 Systemic lupus erythematosus; TGCT cis rs11711311 1.000 rs9811353 chr3:113483979 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs7772486 0.817 rs12198065 chr6:146385286 G/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs28493229 0.708 rs10408309 chr19:41161189 T/G cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs288326 0.561 rs77184695 chr2:183802573 G/A cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs11648796 0.721 rs743987 chr16:769566 C/G cg27144592 chr16:783916 NARFL 0.43 5.82 0.46 4.73e-8 Height; TGCT cis rs72781680 0.950 rs72798404 chr2:24180125 C/T cg08917208 chr2:24149416 ATAD2B 0.9 5.45 0.44 2.62e-7 Lymphocyte counts; TGCT cis rs7786877 0.521 rs4729606 chr7:100321790 T/C cg20848291 chr7:100343083 ZAN -0.52 -4.49 -0.37 1.63e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4850410 0.559 rs13013812 chr2:197908178 C/G cg19149314 chr2:197065128 HECW2 0.23 4.51 0.38 1.46e-5 Interferon alpha levels in systemic lupus erythematosus; TGCT cis rs870825 0.615 rs2696038 chr4:185610903 C/T cg14471096 chr4:185570637 CCDC111;CASP3 -0.67 -4.62 -0.38 9.41e-6 Blood protein levels; TGCT cis rs7829975 0.514 rs2920983 chr8:8268063 G/C cg15556689 chr8:8085844 FLJ10661 0.75 6.8 0.52 4e-10 Mood instability; TGCT cis rs1451375 0.712 rs11974297 chr7:50618260 A/G cg18232548 chr7:50535776 DDC 0.44 7.05 0.53 1.13e-10 Malaria; TGCT cis rs7953249 0.564 rs11065385 chr12:121423386 A/G cg02403541 chr12:121454288 C12orf43 -0.7 -6.33 -0.49 4.11e-9 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs4285028 0.699 rs2689290 chr3:121585146 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.75 -6.71 -0.52 6.29e-10 Multiple sclerosis; TGCT cis rs35306767 0.903 rs61833260 chr10:975148 T/G cg26597838 chr10:835615 NA 0.69 9.59 0.65 1.25e-16 Eosinophil percentage of granulocytes; TGCT cis rs9926296 0.572 rs8047581 chr16:89884502 C/T cg04287289 chr16:89883240 FANCA 0.71 7.57 0.56 7.42e-12 Vitiligo; TGCT cis rs7917772 0.512 rs11594073 chr10:104308193 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.54 -5.31 -0.43 4.96e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs910316 1.000 rs10138183 chr14:75615227 T/C cg08847533 chr14:75593920 NEK9 0.94 10.16 0.67 5.21e-18 Height; TGCT cis rs8072100 0.967 rs8075411 chr17:45676760 C/T cg08085267 chr17:45401833 C17orf57 0.43 4.63 0.38 9.02e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs11122272 0.735 rs2491403 chr1:231511185 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs3008870 0.883 rs2755249 chr1:67493662 A/G cg03991309 chr1:68237761 GNG12 0.27 4.5 0.37 1.56e-5 Lymphocyte percentage of white cells; TGCT cis rs1059312 0.808 rs2170989 chr12:129291317 T/C cg09035930 chr12:129282057 SLC15A4 -0.55 -10.73 -0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs4727027 0.680 rs6464941 chr7:148826352 A/G cg15662616 chr7:148823355 ZNF425;ZNF398 0.57 4.72 0.39 6.24e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3806843 1.000 rs1476768 chr5:140173597 G/A cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs17108533 0.588 rs12882665 chr14:71300599 C/T cg23900759 chr14:71108106 TTC9 1.13 4.56 0.38 1.19e-5 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs1580019 0.844 rs1584615 chr7:32503258 G/C cg06627557 chr7:32535165 LSM5;AVL9 0.88 8.63 0.61 2.55e-14 Cognitive ability; TGCT cis rs919433 0.679 rs10931788 chr2:198531084 A/G cg00792783 chr2:198669748 PLCL1 0.55 4.93 0.4 2.56e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs6088590 1.000 rs2076668 chr20:33437621 G/A cg24642439 chr20:33292090 TP53INP2 0.72 6.38 0.5 3.18e-9 Coronary artery disease; TGCT cis rs9517320 0.515 rs4772101 chr13:99207554 G/A cg07423050 chr13:99094983 FARP1 -0.22 -4.46 -0.37 1.79e-5 Longevity; TGCT cis rs922182 0.617 rs55694045 chr15:64245943 T/C cg02919090 chr15:64263738 DAPK2 0.37 6.84 0.52 3.28e-10 Blood protein levels; TGCT cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg23248424 chr5:179741104 GFPT2 -0.37 -7.04 -0.53 1.17e-10 Height; TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg26354017 chr1:205819088 PM20D1 0.56 6.79 0.52 4.16e-10 Menarche (age at onset); TGCT cis rs12477438 0.765 rs13406288 chr2:99589585 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs3862030 0.503 rs10786673 chr10:104280537 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs112591243 0.685 rs2839366 chr21:48026443 A/T cg10657630 chr21:48055338 PRMT2 -1.08 -6.4 -0.5 2.96e-9 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs350251 0.899 rs350277 chr16:12232547 C/T cg02910054 chr16:12241554 SNX29 0.33 4.57 0.38 1.18e-5 Intelligence (multi-trait analysis); TGCT cis rs753778 0.628 rs1045248 chr8:142204326 C/G cg18755752 chr8:142205143 DENND3 -0.28 -5.02 -0.41 1.78e-6 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9393777 0.841 rs67092078 chr6:27054772 G/A cg16898833 chr6:26189333 HIST1H4D 1.3 5.86 0.47 3.92e-8 Intelligence (multi-trait analysis); TGCT cis rs12479064 0.724 rs4851203 chr2:99986932 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.62 -4.96 -0.41 2.29e-6 Chronic sinus infection; TGCT cis rs7674212 0.570 rs6810571 chr4:104086787 G/T cg16532752 chr4:104119610 CENPE -0.61 -5.67 -0.45 9.45e-8 Type 2 diabetes; TGCT cis rs12477438 0.765 rs12470471 chr2:99689141 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.52 4.45 0.37 1.85e-5 Chronic sinus infection; TGCT cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 -1.08 -9.05 -0.63 2.43e-15 Platelet count; TGCT cis rs6922617 0.892 rs6922692 chr6:41336319 C/G cg07798131 chr6:41471673 NA -0.81 -4.46 -0.37 1.8e-5 Alzheimer's disease biomarkers; TGCT cis rs3935685 0.874 rs4886898 chr15:78004743 T/C cg03457338 chr15:78040120 NA -0.21 -5.54 -0.45 1.72e-7 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs1621090 chr11:49895868 C/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.86e-13 Height; TGCT cis rs9677476 0.657 rs9679430 chr2:232122482 C/T cg27665808 chr2:232055229 NA -0.34 -4.45 -0.37 1.89e-5 Food antigen IgG levels; TGCT cis rs11098499 0.697 rs35280960 chr4:120257059 G/A cg09307838 chr4:120376055 NA 0.66 6.21 0.49 7.37e-9 Corneal astigmatism; TGCT cis rs1635 0.655 rs60568488 chr6:28309511 T/C cg15743358 chr6:28303923 ZNF323 -1.29 -6.5 -0.5 1.73e-9 Schizophrenia; TGCT trans rs12599106 0.792 rs76039834 chr16:34598453 G/A cg01516881 chr6:292596 DUSP22 -0.72 -7.61 -0.56 5.89e-12 Menopause (age at onset); TGCT cis rs12464483 0.591 rs4952170 chr2:30885429 G/A cg17749961 chr2:30669863 LCLAT1 0.69 5.18 0.42 8.66e-7 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT trans rs3780486 0.505 rs7868663 chr9:33141229 A/G cg04842962 chr6:43655489 MRPS18A 0.8 8.6 0.61 2.9e-14 IgG glycosylation; TGCT cis rs72945132 0.882 rs12279046 chr11:70130388 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs3617 0.522 rs6773650 chr3:52897095 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.92 -0.4 2.74e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs28595532 0.764 rs116158926 chr4:119730572 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT trans rs208520 0.690 rs7739253 chr6:66861052 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs7267979 1.000 rs761025 chr20:25426968 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs57590327 0.644 rs7624045 chr3:81510799 A/G cg07356753 chr3:81810745 GBE1 -0.53 -4.44 -0.37 1.97e-5 Extraversion; TGCT cis rs523522 0.885 rs524735 chr12:121022099 T/C cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs910316 0.935 rs11159119 chr14:75636967 C/T cg11812906 chr14:75593930 NEK9 -0.75 -7.44 -0.56 1.43e-11 Height; TGCT cis rs7772486 0.875 rs10457794 chr6:146415608 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs8017423 0.791 rs7146250 chr14:90711703 A/G cg04374321 chr14:90722782 PSMC1 0.75 7.71 0.57 3.51e-12 Mortality in heart failure; TGCT cis rs1801251 1.000 rs7592717 chr2:233577038 G/A cg25237894 chr2:233734115 C2orf82 0.32 5.78 0.46 5.59e-8 Coronary artery disease; TGCT cis rs9443645 0.901 rs10943605 chr6:79655477 G/A cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT trans rs57221529 0.766 rs12522303 chr5:555564 A/C cg25482853 chr8:67687455 SGK3 1.2 10.16 0.67 5.25e-18 Lung disease severity in cystic fibrosis; TGCT cis rs9905704 0.647 rs2286299 chr17:57043367 T/G cg12560992 chr17:57184187 TRIM37 0.59 5.24 0.43 6.8e-7 Testicular germ cell tumor; TGCT cis rs8031584 0.706 rs798084 chr15:31126935 C/T cg08704250 chr15:31115839 NA -0.46 -6.85 -0.52 3.08e-10 Huntington's disease progression; TGCT cis rs10779751 1.000 rs2300093 chr1:11266392 G/C cg08854313 chr1:11322531 MTOR 0.92 10.28 0.68 2.6e-18 Body mass index; TGCT cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs13393800 0.536 rs2741292 chr2:233380999 T/A cg26635044 chr2:233757626 NGEF 0.18 5.0 0.41 1.92e-6 Height; TGCT cis rs4478858 0.735 rs1566964 chr1:31792794 C/A cg00250761 chr1:31883323 NA -0.27 -4.84 -0.4 3.76e-6 Alcohol dependence; TGCT cis rs8084125 0.832 rs62105173 chr18:74947147 A/G cg05528293 chr18:74961138 GALR1 0.48 4.8 0.4 4.45e-6 Obesity-related traits; TGCT cis rs17401966 0.931 rs11587854 chr1:10447622 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.49 -0.44 2.16e-7 Hepatocellular carcinoma; TGCT cis rs933688 1.000 rs332529 chr5:90789470 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.93 7.33 0.55 2.63e-11 Smoking behavior; TGCT cis rs6762 0.550 rs8672 chr11:838634 C/G cg16425592 chr11:842748 TSPAN4;POLR2L -0.45 -4.55 -0.38 1.27e-5 Mean platelet volume; TGCT cis rs2832191 0.729 rs2832201 chr21:30499841 A/G cg24692254 chr21:30365293 RNF160 -0.99 -10.91 -0.7 7.71e-20 Dental caries; TGCT cis rs7666738 0.830 rs13148324 chr4:98833616 G/A cg17366294 chr4:99064904 C4orf37 0.72 7.47 0.56 1.23e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2836633 0.929 rs11701577 chr21:40028906 C/T cg12884169 chr21:40033163 ERG 0.42 4.54 0.38 1.34e-5 Coronary artery disease; TGCT cis rs6967414 0.685 rs6944332 chr7:6758018 G/A cg00387323 chr7:6746715 ZNF12 0.76 4.65 0.39 8.23e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs1008375 0.933 rs6847966 chr4:17634255 G/A cg10189774 chr4:17578691 LAP3 0.65 5.64 0.45 1.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3733585 0.699 rs1122142 chr4:9947548 G/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.45 -0.5 2.22e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7975161 0.572 rs7132418 chr12:104603591 C/A cg25273343 chr12:104657179 TXNRD1 -0.35 -5.13 -0.42 1.07e-6 Toenail selenium levels; TGCT cis rs7523273 0.586 rs2796264 chr1:207919968 A/G cg22525895 chr1:207977042 MIR29B2 0.54 8.81 0.62 9.48e-15 Schizophrenia; TGCT cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg25036284 chr2:26402008 FAM59B -0.61 -4.9 -0.4 2.92e-6 Gut microbiome composition (summer); TGCT cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg18252515 chr7:66147081 NA 1.22 7.98 0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs1453308 0.938 rs2084953 chr2:237178578 T/A cg19324714 chr2:237145437 ASB18 0.58 5.08 0.41 1.36e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs10820904 1.000 rs4743852 chr9:94558126 C/T cg26478992 chr9:95245965 CENPP;ASPN -0.32 -4.47 -0.37 1.77e-5 Body mass index; TGCT cis rs3125734 0.633 rs7100297 chr10:63985100 T/C cg09941381 chr10:64027924 RTKN2 -0.36 -5.53 -0.44 1.83e-7 Rheumatoid arthritis; TGCT cis rs2997447 0.706 rs61776574 chr1:26429492 C/T cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs60843830 0.517 rs58416198 chr2:175580 T/C cg25945732 chr2:264204 ACP1;SH3YL1 0.66 5.12 0.42 1.13e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2456568 0.867 rs4753111 chr11:93658410 A/G cg17595323 chr11:93583763 C11orf90 -0.47 -5.96 -0.47 2.49e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg17554472 chr22:41940697 POLR3H 0.46 4.69 0.39 7.09e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7542091 0.704 rs1108628 chr1:210041150 A/G cg23283495 chr1:209979779 IRF6 0.56 5.59 0.45 1.36e-7 Monobrow; TGCT cis rs933688 1.000 rs1035476 chr5:90745976 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.93 7.95 0.58 1.01e-12 Smoking behavior; TGCT cis rs3741151 1.000 rs74776668 chr11:73065909 G/A cg17517138 chr11:73019481 ARHGEF17 1.08 5.32 0.43 4.75e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT trans rs12599106 0.792 rs76039834 chr16:34598453 G/A cg03395511 chr6:291903 DUSP22 -0.65 -6.76 -0.52 4.71e-10 Menopause (age at onset); TGCT cis rs7267979 1.000 rs398036 chr20:25439850 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7613875 0.620 rs17657664 chr3:50032008 T/G cg21659725 chr3:3221576 CRBN 0.7 7.95 0.58 9.9e-13 Body mass index; TGCT cis rs769267 0.930 rs2099334 chr19:19578450 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.2 0.49 7.59e-9 Tonsillectomy; TGCT cis rs4074961 0.565 rs4415526 chr1:38071728 T/C cg11397548 chr1:38022522 DNALI1 0.41 4.67 0.39 7.69e-6 Axial length; TGCT cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs2019216 0.500 rs4325621 chr17:21926257 T/G cg22648282 chr17:21454238 C17orf51 -0.59 -5.39 -0.44 3.41e-7 Pelvic organ prolapse; TGCT cis rs881375 0.967 rs1008381 chr9:123681116 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.38 4.5 0.37 1.57e-5 Rheumatoid arthritis; TGCT cis rs259282 0.605 rs8101007 chr19:33109557 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.53 4.84 0.4 3.8e-6 Schizophrenia; TGCT cis rs9341808 0.718 rs2322631 chr6:80843956 A/C cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs644799 1.000 rs505220 chr11:95563228 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10465746 0.967 rs12120160 chr1:84342835 T/G cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs918629 0.679 rs57471342 chr5:95272429 A/C cg16656078 chr5:95278638 ELL2 -0.32 -5.06 -0.41 1.49e-6 IgG glycosylation; TGCT cis rs9311474 0.607 rs34005367 chr3:52558904 A/T cg10802521 chr3:52805072 NEK4 -0.73 -8.95 -0.63 4.39e-15 Electroencephalogram traits; TGCT cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Intelligence (multi-trait analysis); TGCT cis rs9517320 0.515 rs72646416 chr13:99232916 C/G cg07423050 chr13:99094983 FARP1 -0.23 -4.54 -0.38 1.31e-5 Longevity; TGCT trans rs561341 1.000 rs55736640 chr17:30333848 G/A cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs4727027 0.870 rs11525060 chr7:148801091 G/A cg23583168 chr7:148888333 NA -0.72 -9.11 -0.63 1.8e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3812831 0.662 rs407531 chr13:114929218 G/A cg15513719 chr13:114904418 NA 0.38 4.65 0.39 8.37e-6 Schizophrenia; TGCT cis rs138857 0.515 rs9616373 chr22:50308597 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.21 -7.42 -0.55 1.6e-11 Mean platelet volume; TGCT trans rs7819412 0.505 rs34031674 chr8:10809490 G/C cg06636001 chr8:8085503 FLJ10661 -0.79 -6.87 -0.53 2.69e-10 Triglycerides; TGCT cis rs4268898 0.795 rs12470303 chr2:24619883 C/T cg02683114 chr2:24398427 C2orf84 -0.19 -4.46 -0.37 1.79e-5 Asthma; TGCT cis rs2180341 1.000 rs9398837 chr6:127635217 G/A cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg13393036 chr8:95962371 TP53INP1 -0.61 -8.31 -0.6 1.42e-13 Type 2 diabetes; TGCT cis rs2948294 0.566 rs13274039 chr8:8111659 A/G cg15462221 chr8:8086144 FLJ10661 -0.58 -4.75 -0.39 5.5e-6 Red cell distribution width; TGCT cis rs1797885 0.546 rs2450855 chr3:12602494 G/A cg05775895 chr3:12838266 CAND2 0.49 4.75 0.39 5.53e-6 Immature fraction of reticulocytes; TGCT cis rs7617480 0.648 rs9864243 chr3:48982732 G/A cg07636037 chr3:49044803 WDR6 0.81 6.68 0.51 7.37e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs244731 0.959 rs9313752 chr5:176645435 G/T cg16006841 chr5:176797999 RGS14 -0.56 -7.2 -0.54 5e-11 Urate levels in lean individuals; TGCT cis rs911263 0.603 rs11626138 chr14:68786993 A/G cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs1609391 0.543 rs6761993 chr3:136625902 C/T cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs17345786 0.906 rs72946021 chr3:101250008 T/G cg12386194 chr3:101231763 SENP7 0.6 5.52 0.44 1.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3008870 1.000 rs3008870 chr1:67418027 C/T cg11518657 chr1:67396239 MIER1 0.54 4.65 0.39 8.44e-6 Lymphocyte percentage of white cells; TGCT cis rs4924935 0.781 rs2472694 chr17:18848498 A/G cg26378065 chr17:18585709 ZNF286B 0.61 4.96 0.41 2.29e-6 Pancreatic cancer; TGCT cis rs4711350 0.954 rs1536501 chr6:33727885 C/T cg00334056 chr6:33755658 LEMD2 0.31 4.82 0.4 4.18e-6 Schizophrenia; TGCT cis rs2594989 0.943 rs2454504 chr3:11498423 G/A cg00170343 chr3:11313890 ATG7 0.67 5.03 0.41 1.69e-6 Circulating chemerin levels; TGCT cis rs79149102 0.579 rs6495135 chr15:75295030 T/C cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs1322512 1.000 rs9371620 chr6:152949230 T/G cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs6671200 0.541 rs7555339 chr1:95691579 G/A cg26537280 chr1:95699037 RWDD3 -0.52 -4.93 -0.4 2.62e-6 Stearic acid (18:0) levels; TGCT cis rs9300255 0.508 rs1716176 chr12:123655467 T/G cg00376283 chr12:123451042 ABCB9 0.66 4.85 0.4 3.59e-6 Neutrophil percentage of white cells; TGCT cis rs76473307 1.000 rs80031754 chr20:57376626 A/G cg06163629 chr20:57414884 GNASAS;GNAS -0.7 -4.61 -0.38 1.01e-5 Chronic lymphocytic leukemia; TGCT cis rs826838 0.935 rs1684406 chr12:39127265 A/G cg13010199 chr12:38710504 ALG10B -0.63 -5.04 -0.41 1.6e-6 Heart rate; TGCT cis rs61931739 0.517 rs10844830 chr12:34308133 C/T cg06521331 chr12:34319734 NA -0.28 -4.7 -0.39 6.74e-6 Morning vs. evening chronotype; TGCT trans rs8073060 0.586 rs6505487 chr17:33996850 A/G cg19694781 chr19:47549865 TMEM160 -0.58 -12.73 -0.75 2.87e-24 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs986417 0.688 rs6573321 chr14:61101710 A/G cg27398547 chr14:60952738 C14orf39 1.57 10.0 0.67 1.28e-17 Gut microbiota (bacterial taxa); TGCT cis rs12908161 0.683 rs12903256 chr15:85308141 G/T cg11189052 chr15:85197271 WDR73 0.62 5.67 0.45 9.56e-8 Schizophrenia; TGCT cis rs7617773 0.643 rs78159520 chr3:48349023 T/C cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs1401999 0.690 rs1402001 chr3:183642751 A/G cg01324343 chr3:183735012 ABCC5 0.69 8.34 0.6 1.23e-13 Anterior chamber depth; TGCT cis rs3008870 0.958 rs12131222 chr1:67438535 A/T cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg05368731 chr17:41323189 NBR1 1.1 11.08 0.71 2.94e-20 Menopause (age at onset); TGCT cis rs9467773 0.967 rs9295694 chr6:26512994 A/T cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs554111 0.656 rs964466 chr1:21375163 T/G cg01072550 chr1:21505969 NA 0.36 5.46 0.44 2.51e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs909674 0.775 rs4821896 chr22:39833437 T/C cg01416388 chr22:39784598 NA -0.74 -6.74 -0.52 5.2e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs3902035 0.964 rs1891713 chr6:119009564 A/G cg07617317 chr6:118971624 C6orf204 -0.43 -5.01 -0.41 1.79e-6 QT interval; TGCT cis rs2046867 0.908 rs11928067 chr3:72796340 T/C cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4930561 0.677 rs7946212 chr11:67982187 T/A cg04465784 chr11:67976953 SUV420H1 -0.38 -5.5 -0.44 2.07e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg10047753 chr17:41438598 NA 0.96 9.49 0.65 2.15e-16 Menopause (age at onset); TGCT cis rs4680 0.737 rs2239393 chr22:19950428 A/G cg23601416 chr22:19950040 COMT -0.39 -5.02 -0.41 1.75e-6 Blood metabolite levels; TGCT cis rs2404602 0.735 rs4886805 chr15:76739384 A/G cg22467129 chr15:76604101 ETFA -0.47 -4.87 -0.4 3.26e-6 Blood metabolite levels; TGCT cis rs782590 0.556 rs782579 chr2:55917604 A/G cg18811423 chr2:55921094 PNPT1 0.56 5.63 0.45 1.13e-7 Metabolic syndrome; TGCT cis rs3806843 0.606 rs251377 chr5:140255792 C/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.43 5.17 0.42 8.91e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs2180341 0.532 rs6933893 chr6:127707250 A/G cg27446573 chr6:127587934 RNF146 0.67 6.07 0.48 1.41e-8 Breast cancer; TGCT cis rs2862064 0.932 rs1995378 chr5:156421132 G/A cg12943317 chr5:156479607 HAVCR1 -0.44 -5.8 -0.46 5.28e-8 Platelet count; TGCT cis rs1218582 0.710 rs4845687 chr1:154878911 A/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.12 -0.54 7.57e-11 Prostate cancer; TGCT cis rs6460942 0.915 rs62447641 chr7:12488764 G/A cg06484146 chr7:12443880 VWDE -0.61 -5.43 -0.44 2.87e-7 Coronary artery disease; TGCT cis rs9915657 0.715 rs34624256 chr17:70105848 C/T cg06234051 chr17:70120541 SOX9 -0.24 -5.14 -0.42 1.03e-6 Thyroid hormone levels; TGCT cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg05738196 chr6:26577821 NA -0.51 -4.92 -0.4 2.71e-6 Schizophrenia; TGCT cis rs9906944 0.603 rs10853104 chr17:47092076 C/T cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.11 -0.42 1.17e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg10150615 chr22:24372951 LOC391322 -1.01 -13.22 -0.76 1.94e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6906287 0.647 rs13217710 chr6:118843601 A/G cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs12532214 1.000 rs12532214 chr7:3169890 C/G cg19214707 chr7:3157722 NA -0.45 -6.11 -0.48 1.19e-8 Itch intensity from mosquito bite; TGCT cis rs4766566 0.501 rs3742004 chr12:111798553 A/G cg10833066 chr12:111807467 FAM109A 0.45 7.72 0.57 3.32e-12 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs7666738 0.606 rs7663216 chr4:99088385 A/C cg17366294 chr4:99064904 C4orf37 0.57 5.31 0.43 4.89e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3796352 0.892 rs2581807 chr3:53088844 G/A cg15956490 chr3:53032818 SFMBT1 -0.54 -6.44 -0.5 2.33e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1322512 1.000 rs1322512 chr6:152947953 C/A cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs57221529 0.766 rs72703042 chr5:579269 C/T cg20362242 chr5:692897 TPPP 0.48 4.51 0.38 1.47e-5 Lung disease severity in cystic fibrosis; TGCT cis rs4822044 0.561 rs132781 chr22:42046122 T/G cg06481639 chr22:41940642 POLR3H 0.73 6.26 0.49 5.81e-9 Cannabis dependence symptom count; TGCT cis rs2832191 0.791 rs2832182 chr21:30481612 G/A cg24692254 chr21:30365293 RNF160 -0.95 -10.52 -0.69 7.06e-19 Dental caries; TGCT cis rs1153858 1.000 rs1346266 chr15:45694516 G/T cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs12682352 0.535 rs12677550 chr8:8644322 A/G cg06636001 chr8:8085503 FLJ10661 -0.6 -5.11 -0.42 1.2e-6 Neuroticism; TGCT cis rs716804 0.740 rs7115944 chr11:10279712 T/C cg17061862 chr11:9590431 NA -0.35 -4.52 -0.38 1.4e-5 Neuroticism; TGCT cis rs7647973 0.667 rs6446286 chr3:49681704 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs853679 0.569 rs9348798 chr6:28143011 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs921968 0.643 rs485765 chr2:219480804 C/G cg02176678 chr2:219576539 TTLL4 0.41 6.14 0.48 1.04e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs7614311 0.509 rs73119034 chr3:63993025 G/A cg22134162 chr3:63841271 THOC7 -0.48 -5.14 -0.42 1.05e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs769267 0.896 rs2315610 chr19:19597240 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.73 0.46 7.3e-8 Tonsillectomy; TGCT cis rs9467711 0.606 rs9393713 chr6:26373678 C/T cg10795676 chr6:26370623 BTN3A2 -0.48 -4.91 -0.4 2.83e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2836974 0.799 rs13047550 chr21:40515495 T/C cg11644478 chr21:40555479 PSMG1 1.0 9.88 0.66 2.54e-17 Cognitive function; TGCT cis rs12142240 1.000 rs12142240 chr1:46747301 T/C cg00530320 chr1:46809349 NSUN4 0.25 4.81 0.4 4.3e-6 Menopause (age at onset); TGCT cis rs7666738 1.000 rs2865983 chr4:99033352 C/T cg17366294 chr4:99064904 C4orf37 0.7 6.56 0.51 1.29e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs10779751 1.000 rs4845987 chr1:11306279 G/C cg08854313 chr1:11322531 MTOR 0.94 10.5 0.69 7.65e-19 Body mass index; TGCT cis rs9527 0.590 rs3740386 chr10:104931051 C/T cg15744005 chr10:104629667 AS3MT -0.4 -4.59 -0.38 1.08e-5 Arsenic metabolism; TGCT cis rs79349575 0.756 rs3848460 chr17:47047114 A/G cg07967210 chr17:47022446 SNF8 -0.44 -5.94 -0.47 2.68e-8 Type 2 diabetes; TGCT cis rs270601 0.739 rs3900945 chr5:131592870 T/C cg12564285 chr5:131593104 PDLIM4 0.4 4.75 0.39 5.41e-6 Acylcarnitine levels; TGCT cis rs6860806 0.507 rs273901 chr5:131694360 G/T cg24060327 chr5:131705240 SLC22A5 -0.77 -8.46 -0.6 6.27e-14 Breast cancer; TGCT cis rs3008870 0.755 rs1024229 chr1:67512903 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.79 7.31 0.55 2.83e-11 Lymphocyte percentage of white cells; TGCT cis rs968451 1.000 rs5750784 chr22:39664180 C/A cg17798944 chr22:39715225 SNORD43;RPL3 0.78 6.76 0.52 4.85e-10 Primary biliary cholangitis; TGCT trans rs12339966 0.550 rs73644521 chr9:11283648 G/T cg03488587 chr11:64876988 C11orf2 0.29 6.64 0.51 8.59e-10 Systolic blood pressure; TGCT cis rs6964587 1.000 rs6950470 chr7:91680641 G/A cg17063962 chr7:91808500 NA 0.88 9.63 0.65 9.8e-17 Breast cancer; TGCT cis rs12477438 0.798 rs6712338 chr2:99585457 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs67311347 1.000 rs28536038 chr3:40496382 A/C cg13683864 chr3:40499215 RPL14 -1.2 -13.25 -0.77 1.68e-25 Renal cell carcinoma; TGCT cis rs826838 0.967 rs7970069 chr12:38810631 T/C cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg13695892 chr22:41940480 POLR3H 0.88 8.63 0.61 2.45e-14 Vitiligo; TGCT cis rs78487399 0.808 rs6732766 chr2:43712785 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.14 -0.42 1.04e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10057188 0.967 rs13181597 chr5:77862388 C/G cg06873401 chr5:77792105 LHFPL2 -0.22 -4.46 -0.37 1.79e-5 Pulse pressure; TGCT cis rs2153535 0.580 rs2225766 chr6:8481833 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.61 0.45 1.24e-7 Motion sickness; TGCT cis rs9467773 1.000 rs4871 chr6:26545632 G/A cg05738196 chr6:26577821 NA 0.88 12.31 0.74 3.11e-23 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs114611353 chr4:119736607 C/T cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs9443645 0.901 rs2174743 chr6:79591805 G/A cg09184832 chr6:79620586 NA -0.51 -5.52 -0.44 1.9e-7 Intelligence (multi-trait analysis); TGCT cis rs2769264 0.546 rs12047617 chr1:151392597 G/A cg18801370 chr1:151430492 POGZ 0.64 6.17 0.48 8.77e-9 Blood trace element (Cu levels); TGCT cis rs2439831 0.867 rs935901 chr15:43651256 G/C cg02155558 chr15:43621948 ADAL;LCMT2 1.1 7.37 0.55 2.1e-11 Lung cancer in ever smokers; TGCT cis rs4862750 0.914 rs6814259 chr4:187872337 T/C cg03452623 chr4:187889614 NA -0.36 -5.24 -0.43 6.6e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4654899 1.000 rs6659152 chr1:21355841 C/G cg01072550 chr1:21505969 NA -0.48 -7.68 -0.57 4.11e-12 Superior frontal gyrus grey matter volume; TGCT cis rs263156 0.874 rs263131 chr6:142943747 G/T cg18419694 chr6:143832440 FUCA2 0.4 4.69 0.39 7.21e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs748404 0.604 rs2278857 chr15:43632549 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.48 5.0 0.41 1.93e-6 Lung cancer; TGCT cis rs9325144 0.560 rs10506125 chr12:39120287 C/T cg26384229 chr12:38710491 ALG10B 0.67 6.47 0.5 2.05e-9 Morning vs. evening chronotype; TGCT cis rs4819052 0.851 rs28676615 chr21:46676576 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9549367 0.713 rs2480949 chr13:113853149 T/C cg09473364 chr13:112927190 NA 0.29 4.64 0.38 8.73e-6 Platelet distribution width; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs782590 0.935 rs782568 chr2:55881538 T/C cg18811423 chr2:55921094 PNPT1 0.64 6.61 0.51 1.04e-9 Metabolic syndrome; TGCT cis rs6582630 0.519 rs8189461 chr12:38374870 G/T cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Drug-induced liver injury (flucloxacillin); TGCT trans rs2688608 0.620 rs12253408 chr10:75495956 G/T cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs769267 0.930 rs4808208 chr19:19650096 A/G cg03709012 chr19:19516395 GATAD2A 0.74 6.04 0.48 1.65e-8 Tonsillectomy; TGCT cis rs2235649 0.592 rs2429186 chr16:1969939 C/T cg02432467 chr16:1963432 HS3ST6 -0.3 -4.5 -0.37 1.53e-5 Blood metabolite levels; TGCT cis rs4372836 0.928 rs55836936 chr2:28922833 T/C cg09522027 chr2:28974177 PPP1CB 0.55 4.48 0.37 1.66e-5 Body mass index; TGCT cis rs6981523 0.553 rs2409730 chr8:11060638 C/A cg21775007 chr8:11205619 TDH -0.51 -4.64 -0.38 8.68e-6 Neuroticism; TGCT trans rs8073060 0.586 rs3859284 chr17:34012792 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2594989 0.733 rs9811482 chr3:11578591 C/T cg00170343 chr3:11313890 ATG7 -0.62 -4.64 -0.38 8.66e-6 Circulating chemerin levels; TGCT cis rs262147 0.610 rs2657363 chr7:158684273 C/T cg11984989 chr7:158649758 WDR60 0.91 5.09 0.42 1.32e-6 Hippocampal volume; TGCT cis rs992157 0.730 rs2382828 chr2:219184492 A/G cg00012203 chr2:219082015 ARPC2 0.69 6.51 0.5 1.7e-9 Colorectal cancer; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg08736216 chr1:53307985 ZYG11A 0.25 4.84 0.4 3.82e-6 Monocyte count; TGCT cis rs10276381 0.786 rs10255700 chr7:28220228 C/T cg23620719 chr7:28220237 JAZF1 0.95 5.75 0.46 6.52e-8 Crohn's disease; TGCT cis rs798554 0.679 rs1614791 chr7:2888057 G/T cg13628971 chr7:2884303 GNA12 0.56 4.71 0.39 6.49e-6 Height; TGCT cis rs453301 0.682 rs2929451 chr8:9085295 A/T cg08975724 chr8:8085496 FLJ10661 0.52 4.69 0.39 7.08e-6 Joint mobility (Beighton score); TGCT cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg21672276 chr3:44754072 ZNF502 -0.41 -4.68 -0.39 7.51e-6 Depressive symptoms; TGCT cis rs9653442 0.712 rs6714788 chr2:100686173 A/G cg07810366 chr2:100720526 AFF3 0.43 7.3 0.55 3.03e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1023500 0.573 rs6002592 chr22:42476754 A/C cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Schizophrenia; TGCT cis rs317689 0.819 rs317685 chr12:69715457 A/G cg20891283 chr12:69753455 YEATS4 -0.55 -4.58 -0.38 1.13e-5 Response to diuretic therapy; TGCT cis rs644799 1.000 rs473148 chr11:95628606 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.75 7.67 0.57 4.37e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs35306767 0.761 rs11253540 chr10:1011958 C/T cg18964960 chr10:1102726 WDR37 -0.67 -4.86 -0.4 3.5e-6 Eosinophil percentage of granulocytes; TGCT cis rs7647973 0.626 rs11130217 chr3:49737323 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs7937682 0.632 rs11214028 chr11:111761149 T/C cg09085632 chr11:111637200 PPP2R1B 0.84 7.26 0.55 3.75e-11 Primary sclerosing cholangitis; TGCT cis rs8077889 0.917 rs72836547 chr17:41902799 G/T cg26893861 chr17:41843967 DUSP3 1.08 12.97 0.76 7.86e-25 Triglycerides; TGCT cis rs2721195 0.967 rs748195 chr8:145682514 T/C cg15857475 chr8:145742913 RECQL4;LRRC14 0.8 8.47 0.61 6.05e-14 Age at first birth; TGCT cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg13695892 chr22:41940480 POLR3H -0.9 -9.01 -0.63 3.17e-15 Vitiligo; TGCT cis rs7100689 0.542 rs10887869 chr10:82194689 A/G cg01528321 chr10:82214614 TSPAN14 0.64 5.35 0.43 4.09e-7 Post bronchodilator FEV1; TGCT cis rs7524258 0.900 rs12035586 chr1:7273020 C/T cg07173049 chr1:7289937 CAMTA1 -0.27 -4.57 -0.38 1.16e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs2153904 0.793 rs12132270 chr1:205660940 C/T cg23034840 chr1:205782522 SLC41A1 -0.72 -4.64 -0.38 8.68e-6 Prostate-specific antigen levels; TGCT cis rs526231 0.543 rs27698 chr5:102526175 C/T cg23492399 chr5:102201601 PAM 0.52 4.49 0.37 1.59e-5 Primary biliary cholangitis; TGCT cis rs5750830 0.649 rs5757663 chr22:39821319 T/C cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.694 rs10791103 chr11:130757161 G/A cg14779329 chr11:130786720 SNX19 0.29 5.02 0.41 1.74e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9807989 0.839 rs4988956 chr2:102968007 G/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs514406 0.505 rs835609 chr1:53170494 T/C cg16325326 chr1:53192061 ZYG11B 0.86 11.87 0.73 3.45e-22 Monocyte count; TGCT cis rs7267979 0.966 rs2257705 chr20:25264664 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1372520 0.627 rs2737025 chr4:90719192 A/G cg26578617 chr4:90757533 SNCA -0.52 -4.44 -0.37 1.99e-5 Neuroticism; TGCT cis rs514406 0.861 rs4926932 chr1:53247495 C/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs3733585 0.699 rs2018643 chr4:9947121 C/T cg00071950 chr4:10020882 SLC2A9 0.54 6.25 0.49 5.99e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9811920 0.570 rs1021102 chr3:99603780 T/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.82 -0.52 3.63e-10 Axial length; TGCT cis rs9790314 0.905 rs4856739 chr3:160986710 A/C cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs2282802 0.685 rs11750229 chr5:139559014 T/G cg01081189 chr5:139537190 NA -0.3 -5.37 -0.43 3.82e-7 Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg03404566 chr17:6899310 ALOX12 0.45 5.1 0.42 1.25e-6 Tonsillectomy; TGCT cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg00684032 chr4:1343700 KIAA1530 0.22 4.9 0.4 2.93e-6 Obesity-related traits; TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg10862848 chr6:42927986 GNMT -0.38 -4.67 -0.39 7.6e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7666738 0.830 rs4699577 chr4:98846513 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.34 0.43 4.23e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg23708337 chr7:1209742 NA 0.31 4.47 0.37 1.77e-5 Longevity;Endometriosis; TGCT cis rs17030434 1.000 rs12646124 chr4:154718084 G/T cg14289246 chr4:154710475 SFRP2 -0.93 -7.08 -0.54 9.34e-11 Electrocardiographic conduction measures; TGCT cis rs346785 0.965 rs164009 chr17:74283669 C/T cg09812376 chr17:74270190 QRICH2 0.39 6.06 0.48 1.51e-8 White matter hyperintensities in ischemic stroke; TGCT cis rs34172651 0.517 rs2303084 chr16:24834581 G/C cg06028605 chr16:24865363 SLC5A11 0.41 4.47 0.37 1.76e-5 Intelligence (multi-trait analysis); TGCT cis rs6938 0.514 rs56338926 chr15:75259335 C/A cg09165964 chr15:75287851 SCAMP5 0.51 4.57 0.38 1.16e-5 Breast cancer; TGCT cis rs11741688 0.557 rs2004503 chr5:178337122 C/T cg08270223 chr5:178322770 ZFP2 -0.37 -5.54 -0.45 1.74e-7 Sleep duration; TGCT cis rs6558530 0.863 rs4595147 chr8:1703569 G/T cg09410841 chr8:1729607 CLN8 0.9 10.36 0.68 1.65e-18 Systolic blood pressure; TGCT cis rs1062177 1.000 rs62394155 chr5:151248069 G/A cg12924095 chr5:151150029 G3BP1 0.34 4.6 0.38 1.04e-5 Preschool internalizing problems; TGCT cis rs12477438 0.798 rs6705821 chr2:99602832 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs2766692 1.000 rs2766692 chr14:100684192 C/T cg14866419 chr14:100704911 YY1 0.57 4.56 0.38 1.21e-5 Electroencephalographic traits in alcoholism; TGCT cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg03806693 chr22:41940476 POLR3H -1.12 -13.03 -0.76 5.66e-25 Vitiligo; TGCT cis rs7909074 0.651 rs10900127 chr10:45390103 C/A cg04218760 chr10:45406644 TMEM72 -0.25 -4.69 -0.39 7.03e-6 Mean corpuscular volume; TGCT cis rs2637266 1.000 rs1907314 chr10:78337948 G/A cg18941641 chr10:78392320 NA 0.4 4.89 0.4 3.07e-6 Pulmonary function; TGCT cis rs2153535 0.580 rs1414340 chr6:8491139 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1372520 0.873 rs2583990 chr4:90771499 A/G cg14346243 chr4:90757452 SNCA -0.63 -5.4 -0.44 3.23e-7 Neuroticism; TGCT cis rs11673344 0.523 rs10420330 chr19:37602171 G/A cg08039142 chr19:36980659 ZNF566 0.52 4.78 0.39 4.96e-6 Obesity-related traits; TGCT cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.31 -0.55 2.86e-11 Colorectal cancer; TGCT cis rs7772486 0.875 rs2814872 chr6:146310234 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.0 0.41 1.91e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1670533 1.000 rs935971 chr4:1045265 G/A cg27284194 chr4:1044797 NA 0.68 5.45 0.44 2.57e-7 Recombination rate (females); TGCT cis rs7586879 0.639 rs2033654 chr2:25103108 C/A cg15423357 chr2:25149977 NA 0.5 4.75 0.39 5.43e-6 Body mass index; TGCT cis rs12188164 0.965 rs72717430 chr5:444502 T/C cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg11905131 chr22:24372483 LOC391322 -0.88 -9.98 -0.67 1.38e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17376456 0.825 rs10075217 chr5:93176774 C/G cg21475434 chr5:93447410 FAM172A 0.73 4.92 0.4 2.66e-6 Diabetic retinopathy; TGCT cis rs911555 0.723 rs4906324 chr14:103923099 A/G cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs7909074 1.000 rs10736831 chr10:45402311 G/A cg05187965 chr10:45406764 TMEM72 -0.24 -5.01 -0.41 1.82e-6 Mean corpuscular volume; TGCT trans rs1814175 0.645 rs7123448 chr11:49764865 T/G cg11707556 chr5:10655725 ANKRD33B -0.45 -11.14 -0.71 2.17e-20 Height; TGCT cis rs704 0.523 rs11080054 chr17:26645991 G/A cg10494684 chr17:26645200 TMEM97 -0.46 -4.96 -0.41 2.32e-6 Osteoprotegerin levels; TGCT cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg02891314 chr5:179741120 GFPT2 -0.41 -7.09 -0.54 8.78e-11 Height; TGCT cis rs8050907 0.744 rs56235717 chr16:4524374 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs7772486 0.875 rs2748485 chr6:146332421 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.98 0.41 2.12e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7613051 0.947 rs13093698 chr3:33063050 A/G cg19000631 chr3:33138515 GLB1;TMPPE 0.64 4.64 0.38 8.56e-6 Atopic dermatitis; TGCT cis rs853679 0.567 rs2232427 chr6:28359709 T/G cg18815343 chr6:28367644 ZSCAN12 -0.52 -4.74 -0.39 5.68e-6 Depression; TGCT cis rs7829975 0.577 rs17684466 chr8:8545233 G/A cg08975724 chr8:8085496 FLJ10661 -0.51 -4.44 -0.37 1.96e-5 Mood instability; TGCT cis rs11190604 1.000 rs4604805 chr10:102261409 C/G cg23241863 chr10:102295624 HIF1AN 0.7 5.33 0.43 4.46e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9611565 0.729 rs505533 chr22:41864216 A/C cg06634786 chr22:41940651 POLR3H 0.81 7.71 0.57 3.43e-12 Vitiligo; TGCT cis rs9814567 0.865 rs9834981 chr3:134282279 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.53 -0.65 1.7e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11264213 0.901 rs10796876 chr1:36424985 A/G cg07093915 chr1:36184400 C1orf216 0.66 4.61 0.38 9.71e-6 Schizophrenia; TGCT cis rs9457247 1.000 rs385863 chr6:167386615 C/G cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs11644362 1.000 rs35325771 chr16:12985138 A/C cg06890432 chr16:12997467 SHISA9 -0.61 -6.72 -0.52 5.93e-10 Positive affect;Subjective well-being; TGCT cis rs9443645 0.869 rs9343848 chr6:79621101 C/T cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.686 rs9373473 chr6:146082282 A/G cg23711669 chr6:146136114 FBXO30 0.8 8.56 0.61 3.71e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.671 rs173763 chr5:56225418 G/A cg12311346 chr5:56204834 C5orf35 -0.57 -6.13 -0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs2806561 0.765 rs605367 chr1:23518524 T/C cg12483005 chr1:23474871 LUZP1 0.38 4.82 0.4 4.09e-6 Height; TGCT cis rs10510102 0.872 rs12240306 chr10:123722906 C/T cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs981844 0.666 rs7691303 chr4:154684198 T/C cg14289246 chr4:154710475 SFRP2 -0.89 -8.19 -0.59 2.73e-13 Response to statins (LDL cholesterol change); TGCT cis rs7937682 0.847 rs11213948 chr11:111464401 G/A cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs6746896 0.843 rs72809827 chr2:97390953 C/T cg26085987 chr2:97230376 NA 0.19 4.72 0.39 6.2e-6 Bipolar disorder; TGCT cis rs11190604 1.000 rs7085439 chr10:102210100 C/T cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs904251 0.523 rs1776454 chr6:37482099 C/T cg08126542 chr6:37504118 NA -0.44 -6.51 -0.5 1.71e-9 Cognitive performance; TGCT cis rs72781680 0.898 rs72796154 chr2:23933839 G/A cg08917208 chr2:24149416 ATAD2B 0.89 5.41 0.44 3.11e-7 Lymphocyte counts; TGCT cis rs875971 1.000 rs6460295 chr7:65882728 T/C cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs9911578 0.803 rs8069033 chr17:57131581 T/A cg05425664 chr17:57184151 TRIM37 0.66 6.66 0.51 7.78e-10 Intelligence (multi-trait analysis); TGCT cis rs3617 0.573 rs13072537 chr3:52896032 C/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.89 -0.4 3e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1372520 0.684 rs2583963 chr4:90727088 C/T cg20003494 chr4:90757398 SNCA -0.66 -5.21 -0.42 7.59e-7 Neuroticism; TGCT cis rs10507380 0.824 rs117209028 chr13:27921999 A/G cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs4242434 0.857 rs11777808 chr8:22462755 A/C cg03733263 chr8:22462867 KIAA1967 1.14 20.09 0.87 8.14e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs17490626 0.568 rs12416520 chr10:71211945 A/G cg14388049 chr10:71211838 TSPAN15 -0.38 -4.48 -0.37 1.7e-5 Thrombosis; TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs611744 0.647 rs13280487 chr8:109270263 G/C cg21045802 chr8:109455806 TTC35 0.7 7.13 0.54 7.42e-11 Dupuytren's disease; TGCT trans rs4332037 0.906 rs6461009 chr7:1952139 T/C cg25206134 chr2:45395956 NA -1.13 -9.64 -0.65 9.5e-17 Bipolar disorder; TGCT cis rs9309473 0.660 rs79370894 chr2:73683515 C/A cg07208825 chr2:73871855 ALMS1P 0.25 4.53 0.38 1.34e-5 Metabolite levels; TGCT cis rs933688 1.000 rs12654787 chr5:90713259 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 8.03 0.58 6.35e-13 Smoking behavior; TGCT cis rs12701220 0.847 rs10272002 chr7:1047615 A/G cg07217954 chr7:1067459 C7orf50 -0.49 -4.76 -0.39 5.27e-6 Bronchopulmonary dysplasia; TGCT cis rs7833790 0.700 rs28390260 chr8:82769175 A/T cg23324259 chr8:82754387 SNX16 0.62 4.71 0.39 6.47e-6 Diastolic blood pressure; TGCT cis rs7617773 1.000 rs6771889 chr3:48194326 C/T cg11946769 chr3:48343235 NME6 -0.6 -5.37 -0.43 3.69e-7 Coronary artery disease; TGCT cis rs7226408 0.857 rs72888908 chr18:34517789 G/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9467711 0.651 rs67554133 chr6:25866232 T/A cg16898833 chr6:26189333 HIST1H4D 1.19 5.48 0.44 2.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7714584 1.000 rs57001853 chr5:150272452 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs7834745 0.578 rs1032128 chr8:119951773 G/A cg17171407 chr8:119960777 TNFRSF11B 0.27 4.45 0.37 1.91e-5 Eosinophil counts;Sum eosinophil basophil counts; TGCT cis rs7666738 0.830 rs11941961 chr4:99065654 G/T cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.652 rs6727974 chr2:26524639 A/G cg04944784 chr2:26401820 FAM59B 0.69 5.68 0.45 8.93e-8 Gut microbiome composition (summer); TGCT cis rs78487399 0.710 rs7561114 chr2:43701951 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs72843506 0.656 rs9913018 chr17:20064072 T/C cg18979559 chr17:20280153 CCDC144C -0.65 -4.87 -0.4 3.33e-6 Schizophrenia; TGCT cis rs2296887 0.673 rs60154233 chr10:104075217 A/G cg26089160 chr10:104170217 PSD -0.56 -5.66 -0.45 9.94e-8 Parkinson's disease; TGCT cis rs17345786 0.906 rs72946021 chr3:101250008 T/G cg11279151 chr3:101281821 RG9MTD1 -0.42 -8.72 -0.62 1.48e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs12220238 0.908 rs10824077 chr10:75887038 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.91 -7.77 -0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT trans rs72913475 0.579 rs112094677 chr18:44180253 T/C cg11874627 chr6:46703554 PLA2G7 0.61 6.7 0.52 6.51e-10 Midgestational circulating levels of PBDEs (fetal genetic effect); TGCT cis rs2153535 0.580 rs6421949 chr6:8531769 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs1691799 0.899 rs1168315 chr12:66746694 A/G cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.87e-9 White blood cell count (basophil); TGCT cis rs5769765 0.773 rs9616378 chr22:50311973 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.44 6.12 0.48 1.13e-8 Schizophrenia; TGCT cis rs9467711 0.675 rs58825580 chr6:26365679 T/G cg16898833 chr6:26189333 HIST1H4D 1.0 5.22 0.42 7.46e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7267979 0.586 rs1007708 chr20:25190959 C/T cg03522245 chr20:25566470 NINL 0.51 5.23 0.43 6.97e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17539620 0.519 rs4077066 chr6:154838448 C/G cg20019720 chr6:154832845 CNKSR3 0.63 5.69 0.45 8.68e-8 Lipoprotein (a) levels; TGCT cis rs7829975 0.777 rs486781 chr8:8639740 A/G cg06636001 chr8:8085503 FLJ10661 -0.68 -5.85 -0.46 4.19e-8 Mood instability; TGCT cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg13012494 chr21:47604986 C21orf56 0.35 4.5 0.37 1.57e-5 Testicular germ cell tumor; TGCT cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.79e-5 Obesity-related traits; TGCT cis rs6912958 0.712 rs7772561 chr6:88331299 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs826838 1.000 rs55828987 chr12:39056421 A/C cg13010199 chr12:38710504 ALG10B 0.77 6.3 0.49 4.68e-9 Heart rate; TGCT cis rs1903068 0.657 rs10026340 chr4:55998136 G/A cg16572876 chr4:56024045 NA 0.44 4.71 0.39 6.48e-6 Endometriosis; TGCT cis rs7666738 0.830 rs34916200 chr4:98851593 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs66573146 1.000 rs28384174 chr4:6961107 G/T cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs7666738 0.830 rs28522896 chr4:99008243 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs78456975 0.506 rs10206900 chr2:1552841 T/C cg12573674 chr2:1569213 NA -0.48 -4.83 -0.4 3.96e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg25036284 chr2:26402008 FAM59B -0.58 -4.61 -0.38 1.01e-5 Gut microbiome composition (summer); TGCT cis rs2549003 1.000 rs2070726 chr5:131821738 C/A cg21138405 chr5:131827807 IRF1 0.19 4.79 0.39 4.76e-6 Asthma (sex interaction); TGCT cis rs910316 1.000 rs1047418 chr14:75605792 A/G cg23033748 chr14:75592666 NEK9 0.29 4.9 0.4 2.95e-6 Height; TGCT cis rs9916302 0.904 rs2024073 chr17:37471330 T/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT trans rs10802346 0.545 rs2362253 chr1:246371676 G/A cg13514129 chr1:39547527 MACF1 0.86 7.71 0.57 3.54e-12 Fractional exhaled nitric oxide (childhood); TGCT cis rs6570726 0.791 rs414297 chr6:145887556 C/T cg05347473 chr6:146136440 FBXO30 0.5 4.63 0.38 9.22e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7224685 0.569 rs12950310 chr17:4001980 T/C cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs11122272 0.735 rs2250704 chr1:231486647 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.88 -0.53 2.66e-10 Hemoglobin concentration; TGCT cis rs6088580 0.602 rs6059840 chr20:33030405 G/A cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs9400467 0.537 rs12202411 chr6:111488518 G/A cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs4919694 0.611 rs75182663 chr10:105058104 A/G cg04362960 chr10:104952993 NT5C2 0.91 6.05 0.48 1.59e-8 Arsenic metabolism; TGCT cis rs4499344 0.730 rs259286 chr19:33164759 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.89 9.69 0.66 7.28e-17 Mean platelet volume; TGCT cis rs12701220 0.894 rs12701406 chr7:1050283 G/A cg07217954 chr7:1067459 C7orf50 -0.49 -4.76 -0.39 5.27e-6 Bronchopulmonary dysplasia; TGCT cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs208520 0.802 rs1342959 chr6:66883329 A/G cg07460842 chr6:66804631 NA -0.9 -9.33 -0.64 5.29e-16 Exhaled nitric oxide output; TGCT cis rs62244186 0.659 rs6441844 chr3:44503579 C/T cg04389838 chr3:44770851 ZNF501 -0.38 -4.94 -0.41 2.42e-6 Depressive symptoms; TGCT cis rs4654899 0.629 rs7515279 chr1:21172774 C/T cg01072550 chr1:21505969 NA 0.53 8.28 0.6 1.66e-13 Superior frontal gyrus grey matter volume; TGCT trans rs66573146 0.831 rs56320732 chr4:6974319 G/A cg07817883 chr1:32538562 TMEM39B 1.42 7.53 0.56 8.92e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs12989701 0.877 rs34854727 chr2:127855392 C/T cg08168897 chr2:127865431 BIN1 0.52 5.53 0.45 1.78e-7 Alzheimer's disease (late onset); TGCT cis rs2811893 1.000 rs232781 chr1:59127637 T/G cg26196860 chr1:59745563 NA 0.25 4.68 0.39 7.49e-6 Diabetic retinopathy; TGCT cis rs10927875 0.662 rs848309 chr1:16308447 T/C cg21385522 chr1:16154831 NA 0.47 5.07 0.41 1.4e-6 Dilated cardiomyopathy; TGCT cis rs13096760 1 rs13096760 chr3:49476806 T/C cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Intelligence (multi-trait analysis); TGCT cis rs6586163 0.872 rs1800682 chr10:90749963 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.38 -4.75 -0.39 5.61e-6 Chronic lymphocytic leukemia; TGCT cis rs9291683 0.609 rs13149985 chr4:10028390 G/A cg11266682 chr4:10021025 SLC2A9 0.66 9.54 0.65 1.61e-16 Bone mineral density; TGCT cis rs554111 0.660 rs667687 chr1:21072577 A/G cg01072550 chr1:21505969 NA -0.31 -4.62 -0.38 9.39e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg04317338 chr11:64019027 PLCB3 0.72 5.52 0.44 1.85e-7 Mean platelet volume; TGCT cis rs9733 0.596 rs6685702 chr1:150656307 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.92 0.4 2.65e-6 Tonsillectomy; TGCT cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg06481639 chr22:41940642 POLR3H 0.69 6.02 0.48 1.83e-8 Vitiligo; TGCT cis rs6882046 0.513 rs34318 chr5:88027149 G/A cg24804195 chr5:87968844 LOC645323 -0.61 -6.24 -0.49 6.2e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs12497850 0.897 rs6795025 chr3:49081247 T/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.51 0.44 2e-7 Parkinson's disease; TGCT cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg12310025 chr6:25882481 NA 0.79 8.09 0.59 4.59e-13 Blood metabolite levels; TGCT cis rs8028182 0.636 rs12708519 chr15:75803200 T/C cg20655648 chr15:75932815 IMP3 0.6 4.65 0.38 8.54e-6 Sudden cardiac arrest; TGCT cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs838147 0.537 rs503279 chr19:49209010 C/T cg05248581 chr19:49925731 PTH2 -0.42 -4.62 -0.38 9.55e-6 Dietary macronutrient intake; TGCT cis rs9653442 0.866 rs12712065 chr2:100761105 C/G cg22139774 chr2:100720529 AFF3 -0.45 -8.11 -0.59 4.08e-13 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs13326165 0.715 rs34355561 chr3:52383120 G/A cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.36e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs295140 0.546 rs295119 chr2:201117944 C/T cg23649088 chr2:200775458 C2orf69 0.33 5.62 0.45 1.21e-7 QT interval; TGCT cis rs7027203 0.828 rs3957506 chr9:96588133 C/T cg14396892 chr9:96623032 NA -0.29 -5.97 -0.47 2.29e-8 DNA methylation (variation); TGCT cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg23708337 chr7:1209742 NA 0.59 5.37 0.43 3.71e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6088580 0.634 rs11700221 chr20:32940320 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.8 -0.4 4.5e-6 Glomerular filtration rate (creatinine); TGCT cis rs881375 0.967 rs7864019 chr9:123692868 A/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.99 0.41 2.03e-6 Rheumatoid arthritis; TGCT cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.59 -0.38 1.06e-5 Bipolar disorder; TGCT cis rs36051895 0.695 rs10974915 chr9:5016818 A/G cg02405213 chr9:5042618 JAK2 -0.75 -9.96 -0.67 1.62e-17 Pediatric autoimmune diseases; TGCT cis rs2274273 0.592 rs2878174 chr14:55470624 T/C cg01923255 chr14:55878535 KIAA0831 0.58 5.14 0.42 1.06e-6 Protein biomarker; TGCT cis rs797680 0.964 rs1932314 chr1:93638400 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.31 -0.43 4.87e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9653442 0.712 rs7582731 chr2:100686486 T/C cg07810366 chr2:100720526 AFF3 -0.43 -7.27 -0.55 3.53e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs6544669 chr2:43736171 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.5 0.37 1.57e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1045714 0.848 rs73033686 chr7:2635085 C/G cg17215154 chr7:2644645 IQCE 0.29 5.12 0.42 1.12e-6 Urate levels in lean individuals; TGCT cis rs7659604 0.539 rs11098648 chr4:122759872 C/T cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.3 -0.43 5.06e-7 Type 2 diabetes; TGCT cis rs4319547 0.661 rs10773172 chr12:122939655 G/A cg05707623 chr12:122985044 ZCCHC8 -0.62 -5.02 -0.41 1.72e-6 Body mass index; TGCT cis rs11971779 0.680 rs2355787 chr7:139089928 G/T cg07862535 chr7:139043722 LUC7L2 -0.58 -4.69 -0.39 6.97e-6 Diisocyanate-induced asthma; TGCT cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg00475322 chr7:917719 C7orf20 0.52 6.95 0.53 1.8e-10 Perceived unattractiveness to mosquitoes; TGCT cis rs7949030 0.590 rs12225213 chr11:62350248 T/A cg22862634 chr11:62369728 EML3;MTA2 0.7 8.83 0.62 8.36e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg12310025 chr6:25882481 NA -0.63 -5.8 -0.46 5.23e-8 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.788 rs4819051 chr21:46693128 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2204008 0.811 rs11520277 chr12:38359611 G/A cg26384229 chr12:38710491 ALG10B 0.78 6.94 0.53 1.91e-10 Bladder cancer; TGCT cis rs9653442 0.564 rs10175599 chr2:100787635 C/T cg07810366 chr2:100720526 AFF3 -0.35 -5.18 -0.42 8.69e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs12893668 0.603 rs61637848 chr14:104096031 C/T cg26031613 chr14:104095156 KLC1 -0.58 -4.86 -0.4 3.5e-6 Reticulocyte count; TGCT cis rs9911578 0.967 rs11079354 chr17:56594460 G/A cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs680134 chr11:95559517 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg23205692 chr1:25664452 TMEM50A 0.51 5.32 0.43 4.69e-7 Erythrocyte sedimentation rate; TGCT cis rs2153535 0.541 rs9328471 chr6:8468842 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs877282 0.838 rs11253373 chr10:774857 A/G cg17470449 chr10:769945 NA 0.3 4.73 0.39 6e-6 Uric acid levels; TGCT cis rs6920965 0.527 rs7763515 chr6:126174714 C/G cg05901451 chr6:126070800 HEY2 -0.58 -5.11 -0.42 1.16e-6 High light scatter reticulocyte count; TGCT cis rs11098499 0.954 rs35091806 chr4:120325529 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs13118159 0.872 rs3903127 chr4:1348806 A/C cg22683308 chr4:1340831 KIAA1530 -0.61 -5.7 -0.46 8.14e-8 Longevity; TGCT cis rs6840360 0.901 rs1443094 chr4:152456724 C/T cg17479576 chr4:152424074 FAM160A1 -0.57 -6.34 -0.49 3.96e-9 Intelligence (multi-trait analysis); TGCT cis rs9393777 0.547 rs2893910 chr6:27283254 A/T cg11262757 chr6:27280423 POM121L2 0.62 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs7172809 0.573 rs1446313 chr15:77475380 G/T cg22256960 chr15:77711686 NA -0.49 -4.63 -0.38 9.01e-6 Glucose homeostasis traits; TGCT cis rs11711311 1.000 rs9854504 chr3:113532381 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.72 -0.52 5.98e-10 IgG glycosylation; TGCT cis rs7666738 0.830 rs4401456 chr4:98959902 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs698813 0.604 rs10865200 chr2:44482884 G/C cg00619915 chr2:44497795 NA -0.24 -5.63 -0.45 1.14e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs6121246 0.909 rs6060821 chr20:30294034 C/T cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs6933660 0.646 rs6915598 chr6:151778664 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.8 -6.59 -0.51 1.11e-9 Menarche (age at onset); TGCT cis rs4478037 0.558 rs73826343 chr3:33067676 C/A cg19404215 chr3:33155277 CRTAP 0.97 4.91 0.4 2.82e-6 Major depressive disorder; TGCT cis rs7769051 1.000 rs7761365 chr6:133101561 T/A cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs3784262 0.669 rs12912093 chr15:58332583 A/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.19 -0.49 8.07e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1801251 1.000 rs1446311 chr2:233705071 G/A cg08000102 chr2:233561755 GIGYF2 -0.63 -6.46 -0.5 2.2e-9 Coronary artery disease; TGCT cis rs13064411 0.696 rs1486897 chr3:113215818 G/A cg18753928 chr3:113234510 CCDC52 -0.69 -5.57 -0.45 1.47e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9303401 0.527 rs7224468 chr17:56749943 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.53 5.05 0.41 1.55e-6 Cognitive test performance; TGCT cis rs34526934 0.608 rs13017511 chr2:177035395 A/G cg14324370 chr2:177042789 NA -0.89 -8.46 -0.61 6.16e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs7267979 0.966 rs454723 chr20:25438928 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9322193 0.923 rs9767309 chr6:150037943 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2361718 0.500 rs4889818 chr17:78085228 A/G cg21238619 chr17:78079768 GAA -0.35 -4.47 -0.37 1.73e-5 Yeast infection; TGCT cis rs25422 0.938 rs114309775 chr6:118838782 G/A cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Renal cell carcinoma; TGCT cis rs10751667 0.666 rs10902241 chr11:949129 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs2658782 1.000 rs2605583 chr11:93164957 T/A cg15737290 chr11:93063684 CCDC67 0.78 5.51 0.44 1.94e-7 Pulmonary function decline; TGCT trans rs7618501 0.521 rs868891 chr3:49949071 A/G cg21659725 chr3:3221576 CRBN 0.68 7.55 0.56 8.1e-12 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.509 rs60698301 chr11:49877672 G/A cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs2066819 1.000 rs2695789 chr12:56694261 C/A cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT trans rs561341 0.556 rs542244 chr17:30307242 T/C cg20587970 chr11:113659929 NA -1.03 -12.39 -0.74 1.92e-23 Hip circumference adjusted for BMI; TGCT cis rs10540 0.908 rs12792111 chr11:520921 G/C cg03934478 chr11:495069 RNH1 0.32 4.82 0.4 4.08e-6 Body mass index; TGCT cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg00786635 chr1:25594202 NA -0.52 -5.56 -0.45 1.59e-7 Erythrocyte sedimentation rate; TGCT cis rs11674184 0.743 rs12470971 chr2:11725241 A/G cg07314298 chr2:11723111 GREB1 0.4 7.58 0.56 7.09e-12 Endometriosis; TGCT cis rs4253772 0.591 rs9627324 chr22:46656511 A/G cg09491104 chr22:46646882 C22orf40 -0.63 -6.39 -0.5 3.05e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg18230493 chr5:56204884 C5orf35 -0.67 -5.75 -0.46 6.54e-8 Initial pursuit acceleration; TGCT cis rs3820068 0.705 rs4646096 chr1:15820758 A/G cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs10744422 0.858 rs7980541 chr12:123379477 C/T cg25930673 chr12:123319894 HIP1R -0.85 -5.03 -0.41 1.69e-6 Schizophrenia; TGCT cis rs1532993 0.518 rs11097571 chr4:98623861 C/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs10791097 0.694 rs11222369 chr11:130744670 A/G cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9330316 0.632 rs919941 chr2:110357351 C/T cg25199208 chr2:109402912 CCDC138 -0.41 -4.44 -0.37 1.99e-5 Schizophrenia; TGCT cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg06238570 chr21:40685208 BRWD1 -0.65 -5.73 -0.46 7.14e-8 Cognitive function; TGCT cis rs7017914 0.905 rs2732113 chr8:71928549 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs644799 1.000 rs627568 chr11:95569253 A/C cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.16 0.59 3.25e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs559928 0.606 rs56311067 chr11:63931607 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.56 0.38 1.22e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs9733 0.818 rs12130363 chr1:150688596 T/C cg13175981 chr1:150552382 MCL1 0.43 4.78 0.39 4.88e-6 Tonsillectomy; TGCT cis rs709400 0.832 rs10145755 chr14:104121984 C/T cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs151997 0.538 rs1345777 chr5:50263788 A/G cg06027927 chr5:50259733 NA -0.57 -5.66 -0.45 9.98e-8 Callous-unemotional behaviour; TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs12477438 0.765 rs1453564 chr2:99564428 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs4409675 0.576 rs6700473 chr1:28236682 C/T cg23691781 chr1:28212827 C1orf38 0.26 5.32 0.43 4.67e-7 Corneal astigmatism; TGCT trans rs2727020 0.702 rs609054 chr11:49219725 C/G cg15704280 chr7:45808275 SEPT13 0.7 7.71 0.57 3.59e-12 Coronary artery disease; TGCT cis rs6088580 0.634 rs6059897 chr20:33113224 A/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs10791097 0.694 rs1893017 chr11:130756253 C/T cg05962950 chr11:130786565 SNX19 0.9 11.06 0.7 3.32e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6714710 0.603 rs2044458 chr2:98377512 A/T cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg26531700 chr6:26746687 NA -0.57 -5.21 -0.42 7.62e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7072216 0.727 rs942809 chr10:100168001 G/A cg26618903 chr10:100175079 PYROXD2 -0.41 -4.5 -0.38 1.51e-5 Metabolite levels; TGCT cis rs875971 0.964 rs2161065 chr7:65932905 A/G cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs1868673 0.623 rs9844184 chr3:150132039 G/A cg24290546 chr3:150134309 TSC22D2 -0.25 -4.67 -0.39 7.66e-6 Waist circumference; TGCT cis rs10984561 0.881 rs10984559 chr9:122256836 G/A cg14242995 chr9:122249943 NA 0.77 6.19 0.49 7.92e-9 Pulmonary function decline; TGCT cis rs13102973 0.646 rs7670551 chr4:135895130 C/T cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs11190604 0.767 rs10883479 chr10:102162860 A/G cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs908922 0.676 rs4845441 chr1:152485421 C/T cg20991723 chr1:152506922 NA 0.47 6.64 0.51 8.74e-10 Hair morphology; TGCT cis rs77633900 0.614 rs1443110 chr15:76928322 C/T cg21673338 chr15:77095150 SCAPER 0.5 4.82 0.4 4.07e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs7917772 0.503 rs7093285 chr10:104374815 G/C cg05855489 chr10:104503620 C10orf26 -0.6 -5.28 -0.43 5.49e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg22520471 chr17:61851767 DDX42;CCDC47 -0.49 -4.58 -0.38 1.09e-5 Prudent dietary pattern; TGCT cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg10295955 chr4:187884368 NA -0.98 -15.16 -0.81 5.3e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs208520 0.661 rs1776361 chr6:66822270 G/A cg07460842 chr6:66804631 NA -0.93 -9.63 -0.65 1e-16 Exhaled nitric oxide output; TGCT cis rs6461049 0.765 rs10224497 chr7:2149967 A/G cg22963979 chr7:1858916 MAD1L1 -0.45 -7.61 -0.56 5.9e-12 Schizophrenia; TGCT cis rs116095464 0.558 rs10080225 chr5:232175 A/G cg22857025 chr5:266934 NA -0.33 -6.57 -0.51 1.22e-9 Breast cancer; TGCT cis rs2303745 0.544 rs6512180 chr19:17399153 C/T cg02221750 chr19:17393354 ANKLE1 -0.46 -5.8 -0.46 5.09e-8 Systemic lupus erythematosus; TGCT cis rs1552244 0.808 rs7615088 chr3:10035896 A/T cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs11122272 0.735 rs2486746 chr1:231497324 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.68 -0.51 7.25e-10 Hemoglobin concentration; TGCT cis rs4836694 0.574 rs4837476 chr9:132937533 T/C cg05251000 chr9:132935664 FREQ 0.55 6.08 0.48 1.36e-8 Alzheimer's disease (cognitive decline); TGCT cis rs854765 0.663 rs4925120 chr17:17754633 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.26 -0.55 3.78e-11 Total body bone mineral density; TGCT cis rs11711311 1.000 rs9811746 chr3:113515060 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs1005277 0.529 rs1780125 chr10:38531376 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6500602 0.739 rs4786502 chr16:4537104 T/C cg08645402 chr16:4508243 NA 0.18 4.88 0.4 3.23e-6 Schizophrenia; TGCT cis rs67072384 0.786 rs58424437 chr11:72448256 C/T cg03713592 chr11:72463424 ARAP1 -0.94 -4.8 -0.4 4.41e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs12210905 0.688 rs72839474 chr6:27324757 T/C cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs9611519 0.780 rs2284079 chr22:41658632 C/T cg06634786 chr22:41940651 POLR3H -0.54 -4.92 -0.4 2.7e-6 Neuroticism; TGCT cis rs1218582 0.774 rs12036859 chr1:154859940 A/C cg24250549 chr1:154909240 PMVK -0.57 -5.55 -0.45 1.67e-7 Prostate cancer; TGCT cis rs12142240 0.698 rs17361833 chr1:46828700 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs61776719 0.875 rs10890238 chr1:38445654 A/T cg12658694 chr1:38397304 INPP5B 0.55 5.78 0.46 5.71e-8 Coronary artery disease; TGCT cis rs1885364 0.574 rs134086 chr22:28067235 A/G cg17187762 chr22:28070120 NA -0.25 -4.57 -0.38 1.15e-5 Facial morphology (factor 8, orbital inclination due to vertical and horizontal position of exocanthion); TGCT cis rs116095464 0.558 rs7356561 chr5:284381 G/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs2692947 0.537 rs12468117 chr2:96194583 C/G cg23100626 chr2:96804247 ASTL 0.45 5.34 0.43 4.21e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs736801 0.538 rs2548998 chr5:131832514 G/A cg02551604 chr5:131831745 NA 0.77 8.55 0.61 3.85e-14 Breast cancer;Mosquito bite size; TGCT cis rs2456568 0.548 rs10765647 chr11:93662459 T/C cg26875233 chr11:93583750 C11orf90 -0.41 -4.94 -0.41 2.43e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs13040088 1.000 rs6090159 chr20:61531351 C/G cg23096297 chr20:61557774 DIDO1 1.17 9.71 0.66 6.25e-17 Menopause (age at onset); TGCT cis rs6089829 0.962 rs9680064 chr20:61666168 G/A cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs12478296 0.681 rs56357900 chr2:243033966 A/C cg06360820 chr2:242988706 NA -0.61 -4.75 -0.39 5.52e-6 Obesity-related traits; TGCT cis rs950027 0.620 rs1145080 chr15:45681338 C/T cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs9814567 0.752 rs4955547 chr3:134334975 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.75 -6.75 -0.52 4.98e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg13397359 chr6:42928475 GNMT 0.71 7.16 0.54 6.35e-11 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs9650657 0.524 rs10088408 chr8:10817197 C/T cg15556689 chr8:8085844 FLJ10661 -0.95 -10.16 -0.67 5.22e-18 Neuroticism; TGCT cis rs9611565 0.592 rs1811113 chr22:42073134 C/T cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Vitiligo; TGCT cis rs3784262 0.527 rs4646557 chr15:58354697 T/C cg12031962 chr15:58353849 ALDH1A2 -0.38 -5.57 -0.45 1.53e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs7647973 0.626 rs35129566 chr3:49866584 T/G cg03060546 chr3:49711283 APEH -0.62 -5.56 -0.45 1.59e-7 Menarche (age at onset); TGCT cis rs12549902 0.800 rs7825337 chr8:41507237 C/T cg21772509 chr8:41503840 NKX6-3 0.8 8.97 0.63 3.91e-15 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs1799949 0.965 rs8176310 chr17:41199913 T/C cg05368731 chr17:41323189 NBR1 0.9 8.95 0.63 4.4e-15 Menopause (age at onset); TGCT cis rs7104764 1.000 rs7481993 chr11:237875 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs3820928 0.845 rs2177596 chr2:227890283 A/T cg11843606 chr2:227700838 RHBDD1 -0.55 -4.97 -0.41 2.19e-6 Pulmonary function; TGCT cis rs9733 0.596 rs6692960 chr1:150695965 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs7617773 0.780 rs7632297 chr3:48348163 A/C cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs9911578 1.000 rs4793950 chr17:56593111 T/C cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs709400 0.628 rs2273700 chr14:103923414 A/G cg12935359 chr14:103987150 CKB -0.36 -5.47 -0.44 2.42e-7 Body mass index; TGCT cis rs7677751 0.806 rs4864857 chr4:55089814 T/C cg17187183 chr4:55093834 PDGFRA 0.55 6.99 0.53 1.48e-10 Corneal astigmatism; TGCT cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg01802117 chr1:53393560 SCP2 0.47 5.77 0.46 5.88e-8 Monocyte count; TGCT cis rs9393777 0.513 rs7759969 chr6:26663096 T/A cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs853679 0.546 rs200954 chr6:27838764 C/G cg08798685 chr6:27730294 NA -0.35 -5.18 -0.42 8.64e-7 Depression; TGCT cis rs2242194 0.816 rs11264296 chr1:154994750 T/C cg06221963 chr1:154839813 KCNN3 -0.49 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs3858526 0.959 rs61876223 chr11:5943393 G/A cg13902645 chr11:5959945 NA -0.46 -4.8 -0.4 4.44e-6 DNA methylation (variation); TGCT cis rs7264396 0.676 rs6058383 chr20:34556005 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs1371867 0.875 rs1371868 chr8:101330267 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs7147624 1.000 rs2411821 chr14:65896914 G/T cg03016385 chr14:66212404 NA -0.5 -7.18 -0.54 5.64e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs12983728 0.831 rs79222418 chr19:58664418 T/C cg07378217 chr19:58662286 ZNF329 -0.82 -4.65 -0.39 8.47e-6 Cholesterol, total; TGCT cis rs4494114 1.000 rs9438984 chr1:39361615 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.18e-9 Blood protein levels; TGCT cis rs4886920 0.722 rs3935182 chr15:78094807 G/C cg25212270 chr15:78015279 NA -0.24 -4.83 -0.4 3.99e-6 Neuroticism; TGCT cis rs854765 0.583 rs4925129 chr17:17807186 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.71 7.76 0.57 2.7e-12 Total body bone mineral density; TGCT cis rs775227 0.574 rs13083453 chr3:113096943 G/A cg18753928 chr3:113234510 CCDC52 -0.65 -4.77 -0.39 5.12e-6 Dental caries; TGCT cis rs71435601 0.628 rs548506 chr2:21385541 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs11148252 0.634 rs1571189 chr13:52731004 A/T cg00495681 chr13:53174319 NA 0.5 4.51 0.38 1.45e-5 Lewy body disease; TGCT cis rs637571 0.565 rs633800 chr11:65638719 G/A cg26695010 chr11:65641043 EFEMP2 0.58 5.85 0.46 4.15e-8 Eosinophil percentage of white cells; TGCT cis rs7267979 0.903 rs2500423 chr20:25374882 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs2727020 0.734 rs1164664 chr11:49295542 T/G cg03929089 chr4:120376271 NA 0.67 6.89 0.53 2.44e-10 Coronary artery disease; TGCT cis rs11098499 0.954 rs12506546 chr4:120301618 T/C cg09307838 chr4:120376055 NA 0.62 5.88 0.47 3.64e-8 Corneal astigmatism; TGCT cis rs4072705 0.562 rs7855918 chr9:127239939 T/C cg13476313 chr9:127244764 NR5A1 0.3 4.81 0.4 4.29e-6 Menarche (age at onset); TGCT cis rs992157 0.717 rs11692780 chr2:219149163 A/G cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT cis rs73058052 0.531 rs3745475 chr19:50100295 A/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.62 0.45 1.19e-7 Fibrinogen levels; TGCT cis rs7178572 0.625 rs12905285 chr15:77845812 T/C cg22256960 chr15:77711686 NA -0.79 -9.06 -0.63 2.33e-15 Type 2 diabetes; TGCT cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs7829975 0.688 rs7826654 chr8:8379106 C/T cg08975724 chr8:8085496 FLJ10661 0.64 6.03 0.48 1.77e-8 Mood instability; TGCT cis rs151997 0.925 rs27260 chr5:50166696 C/T cg06027927 chr5:50259733 NA 0.47 4.77 0.39 5e-6 Callous-unemotional behaviour; TGCT cis rs8014204 0.720 rs34752362 chr14:75232306 G/A cg06637938 chr14:75390232 RPS6KL1 0.71 6.72 0.52 5.98e-10 Caffeine consumption; TGCT cis rs1552244 0.832 rs3732968 chr3:10013273 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.5 -0.5 1.76e-9 Alzheimer's disease; TGCT cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg23205692 chr1:25664452 TMEM50A -0.47 -5.0 -0.41 1.88e-6 Erythrocyte sedimentation rate; TGCT cis rs172166 0.516 rs1225618 chr6:28129713 A/C cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.68 -0.39 7.36e-6 Cardiac Troponin-T levels; TGCT cis rs7439150 0.779 rs80170133 chr4:155476251 C/T cg22130008 chr4:155548532 NA -0.43 -5.43 -0.44 2.87e-7 Fibrinogen levels; TGCT cis rs6933660 0.745 rs6912830 chr6:151743629 A/C cg14262678 chr6:151773367 RMND1;C6orf211 0.49 4.64 0.38 8.89e-6 Menarche (age at onset); TGCT cis rs7914558 1.000 rs10786740 chr10:104935593 G/C cg05855489 chr10:104503620 C10orf26 0.5 4.47 0.37 1.71e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg25767906 chr1:53392781 SCP2 -0.59 -7.49 -0.56 1.12e-11 Monocyte count; TGCT cis rs7666738 0.830 rs28456179 chr4:98991439 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs629535 0.814 rs652483 chr8:70055083 G/A cg21567404 chr3:27674614 NA 0.57 8.67 0.61 2.01e-14 Dupuytren's disease; TGCT cis rs6540559 1.000 rs1044516 chr1:209959614 G/T cg04352962 chr1:209979756 IRF6 0.63 4.74 0.39 5.76e-6 Cleft lip with or without cleft palate; TGCT cis rs116095464 0.558 rs1541822 chr5:269234 A/C cg22857025 chr5:266934 NA 0.34 6.7 0.52 6.46e-10 Breast cancer; TGCT cis rs10927875 0.578 rs10927859 chr1:16141862 C/T cg21385522 chr1:16154831 NA -0.98 -16.54 -0.83 3.72e-33 Dilated cardiomyopathy; TGCT cis rs1799949 1.000 rs11659028 chr17:41195025 T/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 4.84 0.4 3.8e-6 Menopause (age at onset); TGCT trans rs11722228 0.508 rs3822246 chr4:10094698 G/A cg26043149 chr18:55253948 FECH 1.16 11.23 0.71 1.26e-20 Gout;Urate levels;Serum uric acid levels; TGCT trans rs1005277 0.565 rs2474565 chr10:38380828 A/G cg27523141 chr10:43048294 ZNF37B 0.73 8.39 0.6 9.23e-14 Extrinsic epigenetic age acceleration; TGCT cis rs6570726 0.599 rs9403725 chr6:145897622 A/T cg23711669 chr6:146136114 FBXO30 -0.74 -6.97 -0.53 1.62e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10811516 0.501 rs10757193 chr9:21157373 A/G cg23029519 chr9:21187344 IFNA4 -0.29 -4.56 -0.38 1.22e-5 Response to mepolizumab in severe asthma; TGCT cis rs910316 0.763 rs175016 chr14:75459633 C/T cg11812906 chr14:75593930 NEK9 -0.59 -5.69 -0.45 8.84e-8 Height; TGCT cis rs2797160 0.967 rs1578793 chr6:126015057 A/G cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs17376456 0.569 rs7721668 chr5:93290995 G/A cg21475434 chr5:93447410 FAM172A -0.62 -5.97 -0.47 2.3e-8 Diabetic retinopathy; TGCT cis rs7552404 0.727 rs5745433 chr1:76333163 T/G cg10523679 chr1:76189770 ACADM 0.68 6.27 0.49 5.37e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs597539 0.652 rs611046 chr11:68631704 A/G cg06112835 chr11:68658793 MRPL21 0.47 8.01 0.58 7.09e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2980439 0.807 rs2980438 chr8:8094825 T/C cg06636001 chr8:8085503 FLJ10661 0.83 8.25 0.6 1.99e-13 Neuroticism; TGCT cis rs4730250 0.707 rs10253291 chr7:106786550 C/A cg02696742 chr7:106810147 HBP1 0.72 5.93 0.47 2.86e-8 Osteoarthritis; TGCT cis rs1949733 0.701 rs2688222 chr4:8473735 C/A cg13073564 chr4:8508604 NA -0.46 -4.84 -0.4 3.82e-6 Response to antineoplastic agents; TGCT trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg26668828 chr6:292823 DUSP22 -0.76 -7.94 -0.58 1.05e-12 Menopause (age at onset); TGCT cis rs9894429 1.000 rs11652797 chr17:79574124 A/G cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs7917772 0.503 rs7904955 chr10:104367092 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.78 7.97 0.58 9.02e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11690462 0.963 rs12471849 chr2:26559825 C/G cg04726446 chr2:26624865 C2orf39 -0.45 -4.87 -0.4 3.3e-6 Coronary artery disease; TGCT cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.41 2.55e-6 Obesity-related traits; TGCT cis rs1670533 1.000 rs13119276 chr4:1051574 T/C cg20887711 chr4:1340912 KIAA1530 0.72 5.73 0.46 7.16e-8 Recombination rate (females); TGCT cis rs9291683 0.645 rs11557743 chr4:10118377 C/G cg00071950 chr4:10020882 SLC2A9 -0.44 -4.77 -0.39 5.07e-6 Bone mineral density; TGCT cis rs6089829 0.925 rs13041507 chr20:61666180 T/C cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7267979 0.932 rs431579 chr20:25470056 T/C cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9811920 0.638 rs2452321 chr3:99638836 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -7.02 -0.53 1.32e-10 Axial length; TGCT trans rs3780486 0.846 rs7850878 chr9:33126570 A/G cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs7829975 0.606 rs891570 chr8:8794454 G/A cg06636001 chr8:8085503 FLJ10661 -0.73 -6.47 -0.5 2.01e-9 Mood instability; TGCT cis rs7772486 0.902 rs2144476 chr6:146322484 G/A cg23711669 chr6:146136114 FBXO30 0.76 7.98 0.58 8.6e-13 Lobe attachment (rater-scored or self-reported); TGCT cis rs2338224 1.000 rs6452474 chr5:71742179 C/T cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs4237845 0.844 rs7306124 chr12:58303349 A/T cg02175503 chr12:58329896 NA 0.61 6.16 0.48 9.31e-9 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg20637647 chr7:64974828 NA 0.99 5.38 0.44 3.53e-7 Diabetic kidney disease; TGCT cis rs7017914 0.870 rs2639953 chr8:71925660 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs77972916 0.611 rs10495899 chr2:43602304 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.04 -0.48 1.69e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs2456568 0.802 rs11020586 chr11:93638547 G/A cg16099599 chr11:93583650 C11orf90 -0.4 -5.12 -0.42 1.13e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6545883 0.929 rs1900572 chr2:61650715 T/G cg15711740 chr2:61764176 XPO1 0.52 4.62 0.38 9.55e-6 Tuberculosis; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg04234412 chr22:24373322 LOC391322 -0.92 -10.83 -0.7 1.2e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs986417 0.901 rs1061108 chr14:60978071 C/G cg27398547 chr14:60952738 C14orf39 1.48 11.21 0.71 1.46e-20 Gut microbiota (bacterial taxa); TGCT cis rs3749237 1.000 rs2307021 chr3:49765483 C/G cg03060546 chr3:49711283 APEH 0.73 7.58 0.56 7.07e-12 Resting heart rate; TGCT cis rs5750830 0.594 rs5757647 chr22:39775047 C/A cg11247378 chr22:39784982 NA -0.64 -8.48 -0.61 5.71e-14 Intelligence (multi-trait analysis); TGCT cis rs7635838 0.654 rs4684766 chr3:11285474 G/A cg00170343 chr3:11313890 ATG7 0.68 6.58 0.51 1.19e-9 HDL cholesterol; TGCT cis rs7611238 0.538 rs6800221 chr3:195157490 C/G cg27323046 chr3:195102265 ACAP2 0.37 4.97 0.41 2.19e-6 Body mass index; TGCT cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg12756686 chr19:29218302 NA 0.76 6.45 0.5 2.29e-9 Methadone dose in opioid dependence; TGCT cis rs3125734 0.633 rs10761616 chr10:64009076 G/A cg19640130 chr10:64028056 RTKN2 -0.39 -5.02 -0.41 1.78e-6 Rheumatoid arthritis; TGCT cis rs4273100 0.605 rs28591622 chr17:19175317 A/G cg01534423 chr17:18965556 NA 0.79 7.13 0.54 7.34e-11 Schizophrenia; TGCT cis rs7119 0.667 rs2867312 chr15:77902293 A/G cg27398640 chr15:77910606 LINGO1 -0.32 -6.82 -0.52 3.54e-10 Type 2 diabetes; TGCT cis rs11779988 0.543 rs379066 chr8:17881835 T/C cg08627089 chr8:17753878 FGL1 -0.29 -4.57 -0.38 1.18e-5 Breast cancer; TGCT cis rs9811920 0.609 rs4928232 chr3:99694217 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.56 0.51 1.34e-9 Axial length; TGCT cis rs57920188 0.585 rs6703103 chr1:4068320 C/T cg20703997 chr1:4087676 NA 0.48 5.91 0.47 3.14e-8 Interleukin-17 levels; TGCT cis rs17376456 0.877 rs10476526 chr5:93461916 G/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs6424115 1.000 rs2256179 chr1:24132305 A/G cg15997130 chr1:24165203 NA -0.91 -10.39 -0.68 1.4e-18 Immature fraction of reticulocytes; TGCT cis rs13188771 0.690 rs67093064 chr5:100893715 A/T cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7635838 0.892 rs9852530 chr3:11466469 C/T cg00170343 chr3:11313890 ATG7 0.66 6.25 0.49 6.1e-9 HDL cholesterol; TGCT cis rs7914558 0.966 rs3902934 chr10:104746649 A/G cg04362960 chr10:104952993 NT5C2 0.62 5.51 0.44 2.03e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs514406 0.548 rs6670871 chr1:53212082 A/C cg25767906 chr1:53392781 SCP2 0.46 5.11 0.42 1.17e-6 Monocyte count; TGCT cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs9581857 0.547 rs9579096 chr13:28084069 T/C cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT trans rs1814175 0.817 rs7932683 chr11:49983640 G/A cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs4665809 1.000 rs13030858 chr2:26315451 G/A cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs1008375 1.000 rs2058337 chr4:17678649 C/T cg10189774 chr4:17578691 LAP3 0.58 5.3 0.43 5.12e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4819052 0.851 rs2236443 chr21:46678174 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 6.45 0.5 2.32e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg13395646 chr4:1353034 KIAA1530 -0.35 -4.44 -0.37 1.95e-5 Obesity-related traits; TGCT cis rs6545883 0.895 rs6545871 chr2:61692203 G/T cg15711740 chr2:61764176 XPO1 -0.59 -5.43 -0.44 2.79e-7 Tuberculosis; TGCT cis rs13102973 0.720 rs13129730 chr4:135888329 G/A cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs346785 0.692 rs4789274 chr17:74286106 C/T cg09812376 chr17:74270190 QRICH2 -0.37 -5.62 -0.45 1.2e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs6089584 0.566 rs7274240 chr20:60622004 C/T cg06108461 chr20:60628389 TAF4 -0.49 -6.13 -0.48 1.1e-8 Body mass index; TGCT cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg17554472 chr22:41940697 POLR3H 0.53 5.28 0.43 5.58e-7 Vitiligo; TGCT cis rs1570884 0.516 rs2146144 chr13:50170245 C/T cg03651054 chr13:50194643 NA 0.32 5.26 0.43 6.06e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs56235845 0.694 rs4976643 chr5:176760227 A/C cg17509989 chr5:176798049 RGS14 0.55 7.58 0.56 6.89e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs1729951 0.575 rs75976 chr3:136700455 G/A cg21827317 chr3:136751795 NA 0.41 5.78 0.46 5.58e-8 Neuroticism; TGCT cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg27588902 chr6:42928151 GNMT -0.56 -6.87 -0.53 2.77e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9354352 0.784 rs2062327 chr6:66689923 C/G cg07460842 chr6:66804631 NA -0.54 -5.52 -0.44 1.93e-7 Initial pursuit acceleration in psychotic disorders; TGCT cis rs1008375 1.000 rs3733579 chr4:17694943 A/G cg18681998 chr4:17616180 MED28 0.75 7.12 0.54 7.64e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9902453 0.715 rs2628176 chr17:28139292 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.75 -0.52 5.16e-10 Coffee consumption (cups per day); TGCT cis rs3617 0.572 rs2245538 chr3:52852060 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.59 0.38 1.08e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs5769765 0.526 rs5770722 chr22:50253220 G/C cg22709217 chr22:50311962 ALG12;CRELD2 0.97 6.35 0.5 3.69e-9 Schizophrenia; TGCT cis rs28493229 0.522 rs2287692 chr19:41289756 G/A cg11601297 chr19:41224147 ITPKC;ADCK4 0.58 5.1 0.42 1.25e-6 Kawasaki disease; TGCT cis rs1048238 0.818 rs945421 chr1:16345393 T/C cg22431228 chr1:16359049 CLCNKA -0.3 -6.25 -0.49 6.09e-9 Systolic blood pressure; TGCT cis rs6969780 1.000 rs73071550 chr7:27149099 T/C cg04321618 chr7:27170880 HOXA4 0.62 5.21 0.42 7.48e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs514406 0.861 rs2448792 chr1:53268313 T/C cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs4631830 0.965 rs7070301 chr10:51543070 T/G cg10326726 chr10:51549505 MSMB -0.25 -4.89 -0.4 3e-6 Prostate-specific antigen levels; TGCT cis rs4776059 0.761 rs61731670 chr15:52901283 T/C cg25063058 chr15:52860530 ARPP19 -0.56 -4.44 -0.37 1.98e-5 Schizophrenia; TGCT cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs7647973 1.000 rs940045 chr3:49449638 G/A cg07636037 chr3:49044803 WDR6 0.64 5.26 0.43 6.12e-7 Menarche (age at onset); TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg21672276 chr3:44754072 ZNF502 -0.53 -6.25 -0.49 5.98e-9 Depressive symptoms; TGCT cis rs4819052 0.851 rs2838840 chr21:46668494 A/G cg06618935 chr21:46677482 NA -0.37 -5.58 -0.45 1.41e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs57221529 0.664 rs72704802 chr5:554211 C/T cg25482853 chr8:67687455 SGK3 1.21 10.12 0.67 6.64e-18 Lung disease severity in cystic fibrosis; TGCT trans rs561341 1.000 rs55962687 chr17:30260369 C/T cg20587970 chr11:113659929 NA -0.9 -7.84 -0.58 1.78e-12 Hip circumference adjusted for BMI; TGCT cis rs28595532 0.920 rs114019902 chr4:119755564 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6906287 0.647 rs973944 chr6:118850956 T/G cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.73 6.64 0.51 8.93e-10 Prudent dietary pattern; TGCT trans rs931812 0.691 rs884488 chr8:101898523 C/G cg20993868 chr7:22813445 NA 0.34 7.01 0.53 1.37e-10 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs208520 0.954 rs12190073 chr6:66983740 T/C cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT trans rs17685 0.775 rs11761172 chr7:75761547 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1801251 1.000 rs56777991 chr2:233635388 A/C cg08000102 chr2:233561755 GIGYF2 0.64 6.45 0.5 2.22e-9 Coronary artery disease; TGCT trans rs61931739 0.500 rs28692887 chr12:34457075 G/A cg26384229 chr12:38710491 ALG10B 0.73 6.92 0.53 2.09e-10 Morning vs. evening chronotype; TGCT cis rs1949733 0.701 rs940134 chr4:8454870 C/T cg11789530 chr4:8429930 ACOX3 0.54 5.13 0.42 1.08e-6 Response to antineoplastic agents; TGCT cis rs3806843 0.520 rs265312 chr5:140296272 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.43 -5.31 -0.43 4.89e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 0.683 rs62621195 chr8:58133964 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.966 rs2151144 chr20:25414924 G/C cg03522245 chr20:25566470 NINL -0.63 -6.77 -0.52 4.62e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1775715 0.737 rs2808078 chr10:32172552 C/T cg14930904 chr10:32216787 ARHGAP12 0.54 5.3 0.43 5.12e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs1448094 0.556 rs11610627 chr12:86167752 C/T cg02569458 chr12:86230093 RASSF9 0.38 4.49 0.37 1.61e-5 Major depressive disorder; TGCT cis rs67311347 0.544 rs2278929 chr3:40351008 C/G cg13683864 chr3:40499215 RPL14 0.82 7.63 0.57 5.42e-12 Renal cell carcinoma; TGCT cis rs910316 0.967 rs175451 chr14:75589729 C/T cg11812906 chr14:75593930 NEK9 -0.73 -7.13 -0.54 7.35e-11 Height; TGCT cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.83 5.72 0.46 7.43e-8 Alzheimer's disease; TGCT cis rs7666738 0.830 rs6843777 chr4:98866635 T/A cg17366294 chr4:99064904 C4orf37 0.7 7.26 0.55 3.74e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12541335 0.639 rs4565458 chr8:22154133 T/C cg02463440 chr8:22132932 PIWIL2 0.25 4.88 0.4 3.22e-6 Hypertriglyceridemia; TGCT cis rs2067615 0.524 rs4964187 chr12:107080313 C/A cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs6570726 0.846 rs371186 chr6:145886971 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg13699009 chr12:122356056 WDR66 0.23 4.52 0.38 1.43e-5 Mean corpuscular volume; TGCT cis rs13256369 0.851 rs11249889 chr8:8564992 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs208520 0.526 rs9363522 chr6:66816642 C/T cg07460842 chr6:66804631 NA -1.07 -15.41 -0.81 1.34e-30 Exhaled nitric oxide output; TGCT cis rs12681287 0.640 rs13258126 chr8:87453378 G/T cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs6087990 0.806 rs4911108 chr20:31375311 A/G cg13636640 chr20:31349939 DNMT3B 1.05 12.8 0.75 1.94e-24 Ulcerative colitis; TGCT cis rs28595532 0.720 rs72670233 chr4:119316237 C/G cg21605333 chr4:119757512 SEC24D 0.78 4.48 0.37 1.68e-5 Cannabis dependence symptom count; TGCT cis rs476633 0.691 rs28409265 chr15:41539404 G/A cg18705301 chr15:41695430 NDUFAF1 -0.57 -7.34 -0.55 2.47e-11 Glomerular filtration rate (creatinine); TGCT cis rs7267979 0.565 rs3752273 chr20:25594783 A/T cg03522245 chr20:25566470 NINL -0.45 -4.66 -0.39 8.06e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11209002 0.592 rs6672126 chr1:67558063 C/G cg02640540 chr1:67518911 SLC35D1 0.61 5.09 0.42 1.29e-6 Crohn's disease; TGCT cis rs4925386 0.921 rs11204472 chr20:60920887 G/A cg06026331 chr20:60912101 LAMA5 -0.29 -5.38 -0.43 3.61e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs2865977 chr4:99017916 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.06 0.54 1.06e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 1.000 rs10048648 chr2:26320315 T/C cg22920501 chr2:26401640 FAM59B -0.73 -6.28 -0.49 5.18e-9 Gut microbiome composition (summer); TGCT cis rs7267979 0.844 rs2474780 chr20:25285835 G/A cg16686733 chr20:25566563 NINL 0.52 4.93 0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9916302 0.851 rs11078907 chr17:37662954 C/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs514406 0.861 rs1749907 chr1:53259658 C/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT trans rs1866967 0.811 rs4949268 chr1:30186956 C/T cg02311534 chr13:41345535 MRPS31 0.61 6.79 0.52 4.22e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2120019 1.000 rs12910644 chr15:75358388 A/G cg17294928 chr15:75287854 SCAMP5 -0.84 -6.3 -0.49 4.75e-9 Blood trace element (Zn levels); TGCT cis rs12220898 0.703 rs2377977 chr10:50478947 C/T cg06072769 chr10:50146962 WDFY4 0.35 4.5 0.37 1.56e-5 Inflammatory biomarkers; TGCT cis rs259282 0.562 rs28505804 chr19:33110047 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.54 4.91 0.4 2.76e-6 Schizophrenia; TGCT cis rs1865760 0.865 rs9467652 chr6:25959127 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs1372520 0.684 rs2583963 chr4:90727088 C/T cg14346243 chr4:90757452 SNCA -0.68 -5.64 -0.45 1.12e-7 Neuroticism; TGCT cis rs62244186 0.715 rs10212378 chr3:44667286 C/G cg04389838 chr3:44770851 ZNF501 -0.39 -5.15 -0.42 1e-6 Depressive symptoms; TGCT cis rs12950390 1.000 rs8068453 chr17:45852354 A/G cg24803719 chr17:45855879 NA 0.54 4.96 0.41 2.24e-6 IgG glycosylation; TGCT cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs10493773 0.928 rs12741600 chr1:86191172 A/C cg17807903 chr1:86174739 ZNHIT6 -0.42 -5.6 -0.45 1.29e-7 Urate levels in overweight individuals; TGCT cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.9 -6.54 -0.51 1.47e-9 Gut microbiome composition (summer); TGCT cis rs770189 0.628 rs244749 chr5:88140962 T/C cg24804195 chr5:87968844 LOC645323 0.68 4.71 0.39 6.5e-6 Tonometry; TGCT cis rs11098499 0.866 rs7677068 chr4:120291704 C/T cg09307838 chr4:120376055 NA 0.58 5.75 0.46 6.63e-8 Corneal astigmatism; TGCT cis rs6582630 0.519 rs80226845 chr12:38528231 C/A cg13010199 chr12:38710504 ALG10B 0.62 4.95 0.41 2.37e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6840360 0.642 rs11735957 chr4:152427506 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT trans rs208520 1.000 rs72884025 chr6:66994185 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.47 0.56 1.27e-11 Exhaled nitric oxide output; TGCT cis rs1953600 1.000 rs2573346 chr10:81918041 G/A cg04850286 chr10:81895943 PLAC9 -0.39 -4.65 -0.39 8.44e-6 Sarcoidosis; TGCT cis rs7267979 0.808 rs84816 chr20:25459919 G/A cg16686733 chr20:25566563 NINL 0.56 5.57 0.45 1.48e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4253772 0.530 rs715518 chr22:46754177 C/G cg24881330 chr22:46731750 TRMU 1.05 5.39 0.44 3.36e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs473651 1.000 rs473651 chr2:239335401 A/C cg21699342 chr2:239360505 ASB1 0.18 5.01 0.41 1.8e-6 Multiple system atrophy; TGCT cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg12386194 chr3:101231763 SENP7 0.51 4.8 0.4 4.45e-6 Colorectal cancer; TGCT cis rs8103278 1.000 rs7258283 chr19:46335511 C/T cg11657440 chr19:46296263 DMWD -0.6 -5.75 -0.46 6.51e-8 Coronary artery disease; TGCT cis rs295140 0.546 rs295137 chr2:201150040 C/T cg23649088 chr2:200775458 C2orf69 0.27 4.5 0.37 1.53e-5 QT interval; TGCT cis rs7621025 0.500 rs16844241 chr3:136635171 A/G cg15507776 chr3:136538369 TMEM22 -0.68 -6.39 -0.5 3.11e-9 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs28595532 0.920 rs56252481 chr4:119754023 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg01411255 chr17:61851458 DDX42;CCDC47 1.13 14.74 0.8 4.88e-29 Height; TGCT trans rs66573146 1.000 rs6838250 chr4:6973184 C/G cg07817883 chr1:32538562 TMEM39B 1.66 8.29 0.6 1.56e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs9910055 0.708 rs2631298 chr17:42219832 T/C cg19774624 chr17:42201019 HDAC5 -0.87 -10.74 -0.69 1.99e-19 Total body bone mineral density; TGCT trans rs2624839 0.704 rs11919418 chr3:50233215 T/G cg21665057 chr3:196295764 WDR53;FBXO45 0.84 8.12 0.59 3.98e-13 Intelligence (multi-trait analysis); TGCT cis rs6430585 0.583 rs9636213 chr2:136589278 G/A cg07169764 chr2:136633963 MCM6 -1.05 -9.58 -0.65 1.28e-16 Corneal structure; TGCT cis rs1857353 1.000 rs114865780 chr1:75871055 T/C cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs8141529 0.719 rs5762880 chr22:29287816 T/G cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs2439831 1.000 rs101094 chr15:43787322 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.19 0.59 2.67e-13 Lung cancer in ever smokers; TGCT cis rs7178572 0.568 rs12901739 chr15:77395491 C/T cg22256960 chr15:77711686 NA -0.86 -8.84 -0.62 8.05e-15 Type 2 diabetes; TGCT cis rs12477438 0.559 rs6733285 chr2:99725575 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs6500602 0.627 rs860891 chr16:4586529 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.39 -5.68 -0.45 9.26e-8 Schizophrenia; TGCT trans rs1814175 0.935 rs11040463 chr11:49685574 C/T cg03929089 chr4:120376271 NA -0.63 -7.04 -0.53 1.14e-10 Height; TGCT cis rs6815814 0.851 rs73235002 chr4:38769018 A/G cg02016764 chr4:38805732 TLR1 -0.33 -5.25 -0.43 6.31e-7 Breast cancer; TGCT cis rs1497406 0.773 rs7538833 chr1:16504381 T/C cg20430773 chr1:16534157 ARHGEF19 0.51 5.65 0.45 1.04e-7 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7662987 0.540 rs2851278 chr4:100021253 G/C cg12011299 chr4:100065546 ADH4 0.42 4.92 0.4 2.64e-6 Smoking initiation; TGCT cis rs610932 0.517 rs676309 chr11:60001573 A/G cg18570331 chr11:60101691 MS4A6E 0.51 4.6 0.38 1.04e-5 Alzheimer's disease; TGCT cis rs4713118 0.621 rs9295755 chr6:28033174 C/T cg12963246 chr6:28129442 ZNF389 -0.48 -4.89 -0.4 3.01e-6 Parkinson's disease; TGCT cis rs7714584 1.000 rs2004711 chr5:150225068 C/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs6674176 0.628 rs7556565 chr1:44416090 C/T cg13606994 chr1:44402422 ARTN -0.46 -4.98 -0.41 2.12e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs74181299 0.571 rs12990465 chr2:65281401 C/T cg05010058 chr2:65284262 CEP68 0.49 5.01 0.41 1.79e-6 Pulse pressure; TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg17345569 chr6:42928274 GNMT -0.47 -4.92 -0.4 2.65e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4851266 1.000 rs11123817 chr2:100835032 C/T cg07810366 chr2:100720526 AFF3 -0.39 -5.73 -0.46 7.19e-8 Educational attainment; TGCT cis rs4478858 0.698 rs4949385 chr1:31793256 C/T cg00250761 chr1:31883323 NA -0.27 -4.84 -0.4 3.76e-6 Alcohol dependence; TGCT cis rs2658782 0.789 rs56091149 chr11:93073640 A/C cg18152523 chr11:93063302 CCDC67 0.71 5.2 0.42 8.11e-7 Pulmonary function decline; TGCT cis rs11671005 0.735 rs34873624 chr19:58943402 G/A cg13877915 chr19:58951672 ZNF132 0.63 5.0 0.41 1.95e-6 Mean platelet volume; TGCT cis rs72634258 0.503 rs71637401 chr1:7837012 G/A cg26816564 chr1:7831052 VAMP3 0.97 6.95 0.53 1.88e-10 Inflammatory bowel disease; TGCT cis rs933688 0.938 rs7720235 chr5:90659329 A/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.13 10.03 0.67 1.06e-17 Smoking behavior; TGCT cis rs1372520 0.766 rs2583961 chr4:90779758 A/G cg01966878 chr4:90757139 SNCA -0.3 -4.77 -0.39 5.1e-6 Neuroticism; TGCT cis rs2832191 0.791 rs2832196 chr21:30497412 G/A cg08807101 chr21:30365312 RNF160 -0.62 -5.8 -0.46 5.14e-8 Dental caries; TGCT cis rs17001868 0.568 rs9607702 chr22:40739177 A/G cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg09904177 chr6:26538194 HMGN4 0.6 5.15 0.42 1.01e-6 Intelligence (multi-trait analysis); TGCT cis rs7647973 1.000 rs13088309 chr3:49368317 A/G cg07636037 chr3:49044803 WDR6 0.72 5.84 0.46 4.25e-8 Menarche (age at onset); TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg01802117 chr1:53393560 SCP2 -0.44 -5.45 -0.44 2.6e-7 Monocyte count; TGCT cis rs7246657 0.765 rs7247259 chr19:37851090 T/C cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.3e-7 Coronary artery calcification; TGCT cis rs9972944 0.589 rs11870559 chr17:63772633 G/A cg07283582 chr17:63770753 CCDC46 0.25 4.57 0.38 1.14e-5 Total body bone mineral density; TGCT cis rs7647973 0.710 rs11130207 chr3:49611666 T/G cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs7412746 0.634 rs3754212 chr1:150738200 A/G cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs7731657 0.537 rs13355768 chr5:130360245 C/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs4888262 0.545 rs7193959 chr16:74664969 T/A cg01733217 chr16:74700730 RFWD3 0.74 7.38 0.55 1.99e-11 Testicular germ cell tumor; TGCT cis rs9527 0.615 rs7899622 chr10:104727333 C/T cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs319204 0.885 rs575571 chr5:146287354 A/C cg25021259 chr5:146258546 PPP2R2B 0.35 4.45 0.37 1.89e-5 Schizophrenia; TGCT cis rs6089829 1.000 rs6089828 chr20:61668998 C/T cg03213289 chr20:61660250 NA 0.68 9.59 0.65 1.23e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs295140 1.000 rs11696001 chr2:201162433 G/A cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs801193 0.660 rs10950049 chr7:66230860 T/C cg11764359 chr7:65958608 NA 0.56 4.7 0.39 6.69e-6 Aortic root size; TGCT cis rs6912958 0.515 rs381782 chr6:88040649 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.7 7.17 0.54 5.95e-11 Monocyte percentage of white cells; TGCT cis rs7927771 0.832 rs10838699 chr11:47386073 T/C cg21462715 chr11:47870315 NUP160 -0.56 -4.52 -0.38 1.4e-5 Subjective well-being; TGCT cis rs7014346 0.767 rs11778075 chr8:128421128 G/T cg04263511 chr8:128962092 PVT1 -0.31 -4.55 -0.38 1.25e-5 Colorectal cancer; TGCT cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs8042680 0.592 rs11073960 chr15:91483257 C/G cg23684204 chr15:91497937 RCCD1 0.29 4.44 0.37 1.98e-5 Type 2 diabetes; TGCT cis rs2078087 0.790 rs12035803 chr1:183466305 T/C cg16263152 chr1:183287819 NMNAT2 0.41 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs72781680 1.000 rs72798408 chr2:24181845 G/C cg08917208 chr2:24149416 ATAD2B 0.84 5.13 0.42 1.1e-6 Lymphocyte counts; TGCT cis rs2032447 0.867 rs9295683 chr6:26069495 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.95 9.63 0.65 9.9900000000000006e-17 Intelligence (multi-trait analysis); TGCT cis rs13191362 0.935 rs13215748 chr6:163010710 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9527 0.590 rs3781282 chr10:104852419 C/T cg15744005 chr10:104629667 AS3MT 0.45 5.29 0.43 5.44e-7 Arsenic metabolism; TGCT cis rs12145833 0.538 rs4658547 chr1:243391131 T/G cg02356786 chr1:243265016 LOC731275 -0.59 -5.11 -0.42 1.18e-6 Obesity (early onset extreme); TGCT cis rs875971 0.862 rs28491091 chr7:65669064 G/T cg11764359 chr7:65958608 NA -0.53 -4.7 -0.39 6.81e-6 Aortic root size; TGCT cis rs13188771 0.690 rs67093064 chr5:100893715 A/T cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs13242816 1.000 rs34234085 chr7:116114066 G/A cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs2072499 0.931 rs1052053 chr1:156202173 A/G cg06970220 chr1:156163860 SLC25A44 0.65 5.95 0.47 2.51e-8 Testicular germ cell tumor; TGCT cis rs4434138 0.594 rs7653028 chr3:52763000 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.21 0.49 7.27e-9 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg11502198 chr6:26597334 ABT1 -0.54 -4.96 -0.41 2.25e-6 Intelligence (multi-trait analysis); TGCT cis rs6964587 0.708 rs38800 chr7:92046191 C/G cg17063962 chr7:91808500 NA -0.59 -4.99 -0.41 2.03e-6 Breast cancer; TGCT cis rs9611565 0.649 rs5751144 chr22:42128097 A/G cg06634786 chr22:41940651 POLR3H -0.82 -7.9 -0.58 1.3e-12 Vitiligo; TGCT cis rs13217239 0.646 rs4403259 chr6:26997617 C/T cg02458000 chr6:26745757 NA 0.5 4.61 0.38 1e-5 Schizophrenia; TGCT cis rs2455799 0.559 rs11128768 chr3:15923990 A/G cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs13191362 1.000 rs13214516 chr6:163121583 A/T cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.17 0.59 3.08e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.96 7.96 0.58 9.51e-13 Platelet count; TGCT cis rs4664308 0.710 rs13001911 chr2:161020703 G/C cg03641300 chr2:160917029 PLA2R1 -0.21 -4.84 -0.4 3.83e-6 Idiopathic membranous nephropathy; TGCT cis rs6684514 1.000 rs7522948 chr1:156275308 C/T cg20302342 chr1:156215951 PAQR6 0.33 4.54 0.38 1.34e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1215050 0.682 rs6839343 chr4:98839732 G/A cg05340658 chr4:99064831 C4orf37 0.47 4.9 0.4 2.94e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3772130 0.962 rs9812137 chr3:121539103 T/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs10465746 0.780 rs12145258 chr1:84401211 G/A cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT cis rs7666738 0.830 rs11731478 chr4:99001686 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs2239815 0.515 rs6005917 chr22:29233486 A/G cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs933688 1.000 rs1541674 chr5:90660447 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.99 9.32 0.64 5.44e-16 Smoking behavior; TGCT cis rs3617 0.591 rs11918800 chr3:52868145 G/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs12142240 0.698 rs72677596 chr1:46833930 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.87 -0.4 3.31e-6 Menopause (age at onset); TGCT cis rs7193541 0.684 rs4888262 chr16:74670458 C/T cg01733217 chr16:74700730 RFWD3 1.02 14.05 0.78 2.05e-27 Multiple myeloma; TGCT cis rs832540 0.931 rs832529 chr5:56229288 C/T cg24531977 chr5:56204891 C5orf35 -0.49 -5.03 -0.41 1.66e-6 Coronary artery disease; TGCT cis rs617219 0.710 rs10474578 chr5:78542290 T/C cg05890484 chr5:78407552 BHMT 0.34 4.63 0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs12421382 0.659 rs56410856 chr11:109382455 T/G cg16359550 chr11:109292809 C11orf87 0.4 4.5 0.37 1.54e-5 Schizophrenia; TGCT cis rs6095298 0.595 rs34280360 chr20:47454171 G/A cg12307787 chr20:48099359 KCNB1 0.42 4.51 0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs981844 0.775 rs62323977 chr4:154746141 G/A cg14289246 chr4:154710475 SFRP2 1.0 8.63 0.61 2.53e-14 Response to statins (LDL cholesterol change); TGCT cis rs7617773 0.778 rs11715776 chr3:48377611 G/C cg11946769 chr3:48343235 NME6 0.82 6.99 0.53 1.49e-10 Coronary artery disease; TGCT cis rs4595586 0.545 rs11609541 chr12:39378331 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2688608 1.000 rs2688608 chr10:75658349 G/T cg04320760 chr10:75533139 FUT11 -0.3 -4.63 -0.38 9.21e-6 Inflammatory bowel disease; TGCT cis rs7267979 0.816 rs422148 chr20:25512604 G/C cg16686733 chr20:25566563 NINL 0.52 5.05 0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs909674 0.524 rs5757670 chr22:39829736 G/A cg24399712 chr22:39784796 NA -1.04 -12.23 -0.74 4.8e-23 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9914544 0.545 rs1037037 chr17:18765021 A/G cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.55e-5 Educational attainment (years of education); TGCT cis rs9868809 0.772 rs9877501 chr3:48718390 C/G cg00383909 chr3:49044727 WDR6 0.88 5.29 0.43 5.32e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7769051 0.522 rs60631157 chr6:133094817 G/A cg22852734 chr6:133119734 C6orf192 1.16 4.48 0.37 1.67e-5 Type 2 diabetes nephropathy; TGCT cis rs875971 1.000 rs3735148 chr7:65971009 T/G cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs10883723 0.669 rs2001595 chr10:104395085 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 7.62 0.56 5.71e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs986417 1.000 rs1956557 chr14:60972569 G/A cg27398547 chr14:60952738 C14orf39 1.49 10.81 0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs13191362 1.000 rs13213408 chr6:162998049 A/T cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6598955 0.585 rs6659822 chr1:26626408 C/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs13118159 0.836 rs2293630 chr4:1342521 G/A cg13395646 chr4:1353034 KIAA1530 -0.4 -4.66 -0.39 7.96e-6 Longevity; TGCT cis rs1519814 0.696 rs7386139 chr8:121027419 C/T cg22335954 chr8:121166405 COL14A1 -0.36 -4.56 -0.38 1.21e-5 Breast cancer; TGCT cis rs1372520 1.000 rs1372520 chr4:90757505 T/C cg20003494 chr4:90757398 SNCA -0.67 -5.31 -0.43 4.84e-7 Neuroticism; TGCT cis rs12478296 0.681 rs73007114 chr2:242984903 T/C cg06360820 chr2:242988706 NA -0.91 -5.53 -0.44 1.83e-7 Obesity-related traits; TGCT cis rs1008375 1.000 rs11722037 chr4:17683811 G/A cg10189774 chr4:17578691 LAP3 0.51 4.77 0.39 5.04e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4803468 1.000 rs10409485 chr19:41920765 C/T cg09537434 chr19:41945824 ATP5SL 0.88 10.19 0.68 4.28e-18 Height; TGCT cis rs61990749 0.597 rs759808 chr14:78250845 T/G cg23188588 chr14:78226832 SNW1;C14orf178 0.64 4.5 0.37 1.54e-5 Fibroblast growth factor basic levels; TGCT cis rs35883536 1.000 rs1577508 chr1:101089289 T/C cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.22e-5 Monocyte count; TGCT trans rs2727020 0.729 rs2204366 chr11:49349367 A/C cg15704280 chr7:45808275 SEPT13 0.72 7.95 0.58 9.78e-13 Coronary artery disease; TGCT cis rs72720396 0.803 rs115552537 chr1:91190856 C/A cg13456504 chr1:91191583 NA 0.74 5.83 0.46 4.57e-8 Morning vs. evening chronotype;Chronotype; TGCT cis rs501916 1.000 rs599111 chr15:48053334 G/T cg16110827 chr15:48056943 SEMA6D -0.17 -5.15 -0.42 9.79e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT trans rs2727020 0.576 rs12293522 chr11:49558425 T/A cg03929089 chr4:120376271 NA -0.77 -9.31 -0.64 5.96e-16 Coronary artery disease; TGCT cis rs4455778 0.659 rs7796932 chr7:49057745 C/T cg26309511 chr7:48887640 NA 0.44 5.12 0.42 1.13e-6 Lung cancer in never smokers; TGCT cis rs1171582 0.526 rs1913507 chr10:61518989 C/T cg23572703 chr10:62241191 NA -0.26 -4.46 -0.37 1.84e-5 Alopecia areata; TGCT trans rs208520 0.955 rs17644076 chr6:67004973 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.73 -6.63 -0.51 9.12e-10 Exhaled nitric oxide output; TGCT cis rs651907 0.557 rs7612283 chr3:101434919 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 10.45 0.68 1.02e-18 Colorectal cancer; TGCT cis rs7213347 0.610 rs8077194 chr17:2119475 A/G cg13315690 chr17:1944831 OVCA2;DPH1 -0.39 -4.97 -0.41 2.16e-6 Total body bone mineral density; TGCT cis rs308403 0.568 rs13138426 chr4:123652580 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.7 6.41 0.5 2.8e-9 Blood protein levels; TGCT cis rs79996792 0.736 rs79299044 chr2:162494182 T/A cg22496339 chr2:162101262 NA 0.54 4.54 0.38 1.3e-5 Neuroticism; TGCT cis rs9611565 1.000 rs1109151 chr22:41752944 A/G cg06634786 chr22:41940651 POLR3H -0.78 -7.47 -0.56 1.23e-11 Vitiligo; TGCT cis rs66782572 1 rs66782572 chr3:52567617 A/G cg10802521 chr3:52805072 NEK4 -0.65 -7.63 -0.57 5.37e-12 Hemoglobin concentration; TGCT cis rs2594989 0.943 rs2454501 chr3:11500089 A/G cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.58e-5 Circulating chemerin levels; TGCT cis rs61867294 0.794 rs7901022 chr10:106656680 A/G cg08000847 chr10:105880925 C10orf78 -0.57 -4.6 -0.38 1.04e-5 Schizophrenia; TGCT cis rs7772486 0.686 rs702305 chr6:145973840 A/G cg23711669 chr6:146136114 FBXO30 -0.83 -9.29 -0.64 6.68e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7829975 0.572 rs28730413 chr8:8795447 A/C cg06636001 chr8:8085503 FLJ10661 -0.76 -7.17 -0.54 5.83e-11 Mood instability; TGCT cis rs112591243 0.685 rs73379602 chr21:48027317 G/A cg10657630 chr21:48055338 PRMT2 0.95 6.19 0.49 8.21e-9 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs936229 0.668 rs67411922 chr15:75187612 A/G cg10253484 chr15:75165896 SCAMP2 -0.77 -6.49 -0.5 1.85e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs595982 0.527 rs12151238 chr19:49368613 T/C cg21252483 chr19:49399788 TULP2 -0.42 -6.39 -0.5 3.02e-9 Red cell distribution width; TGCT cis rs826838 1.000 rs1684416 chr12:39130301 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs4455778 0.508 rs38776 chr7:48938570 G/C cg26309511 chr7:48887640 NA 0.54 6.06 0.48 1.54e-8 Lung cancer in never smokers; TGCT cis rs6901250 0.819 rs9374623 chr6:117127312 C/A cg12892004 chr6:117198278 RFX6 0.54 6.6 0.51 1.05e-9 C-reactive protein levels; TGCT cis rs6933660 0.683 rs8180642 chr6:151756612 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.6 5.71 0.46 7.95e-8 Menarche (age at onset); TGCT cis rs1799949 0.894 rs71367985 chr17:41374463 G/A cg23758822 chr17:41437982 NA 0.69 6.71 0.52 6.07e-10 Menopause (age at onset); TGCT cis rs1205863 1.000 rs1205866 chr6:11943775 C/A cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg11965913 chr1:205819406 PM20D1 0.47 6.39 0.5 3.09e-9 Menarche (age at onset); TGCT cis rs6088580 0.634 rs6119497 chr20:33012529 T/A cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs7584330 0.554 rs6706729 chr2:238398580 T/C cg14458575 chr2:238380390 NA 0.67 5.5 0.44 2.09e-7 Prostate cancer; TGCT cis rs11955175 1.000 rs75929994 chr5:40821816 T/C cg17351974 chr5:40835760 RPL37 0.87 5.92 0.47 2.98e-8 Bipolar disorder and schizophrenia; TGCT cis rs2120019 0.938 rs1867150 chr15:75321139 T/C cg11632617 chr15:75315747 PPCDC -0.3 -4.44 -0.37 1.95e-5 Blood trace element (Zn levels); TGCT cis rs62012628 0.527 rs12437868 chr15:79088460 T/C cg04896959 chr15:78267971 NA -0.33 -5.73 -0.46 7.28e-8 Diastolic blood pressure; TGCT cis rs6430585 0.583 rs2839740 chr2:136648883 G/T cg07169764 chr2:136633963 MCM6 1.22 11.92 0.73 2.63e-22 Corneal structure; TGCT cis rs4713118 0.621 rs4713132 chr6:28034035 A/G cg12963246 chr6:28129442 ZNF389 0.48 4.79 0.4 4.58e-6 Parkinson's disease; TGCT cis rs926938 0.765 rs12407408 chr1:115234275 A/G cg12756093 chr1:115239321 AMPD1 0.42 6.23 0.49 6.61e-9 Autism; TGCT cis rs9611565 0.592 rs80477 chr22:42001183 C/T cg03806693 chr22:41940476 POLR3H 1.02 10.38 0.68 1.54e-18 Vitiligo; TGCT cis rs9354352 0.967 rs6455062 chr6:66694131 T/A cg07460842 chr6:66804631 NA 0.65 6.68 0.51 7.29e-10 Initial pursuit acceleration in psychotic disorders; TGCT cis rs9902453 0.845 rs62068583 chr17:28001482 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.76e-11 Coffee consumption (cups per day); TGCT cis rs9653442 0.900 rs2309837 chr2:100837567 T/C cg07810366 chr2:100720526 AFF3 -0.4 -6.06 -0.48 1.49e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs477895 1.000 rs2286614 chr11:64068310 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.65 4.95 0.41 2.36e-6 Mean platelet volume; TGCT cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg15691649 chr6:25882328 NA 0.49 5.98 0.47 2.17e-8 Blood metabolite levels; TGCT cis rs17711722 0.565 rs4275112 chr7:65198619 T/G cg07424592 chr7:64974309 NA 0.65 6.41 0.5 2.8e-9 Calcium levels; TGCT cis rs6076065 0.630 rs6083127 chr20:23424886 T/C cg11657817 chr20:23433608 CST11 0.35 6.59 0.51 1.14e-9 Facial morphology (factor 15, philtrum width); TGCT cis rs2692947 0.673 rs2917662 chr2:96794957 G/A cg23100626 chr2:96804247 ASTL 0.47 5.61 0.45 1.28e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs78545713 1.000 rs3734534 chr6:26240649 A/G cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI 0.61 4.61 0.38 9.8200000000000008e-06 Iron status biomarkers (total iron binding capacity); TGCT cis rs10832169 0.933 rs1406356 chr11:14077511 A/T cg04547675 chr11:13986162 SPON1 -0.5 -4.5 -0.37 1.57e-5 Blood protein levels; TGCT cis rs2898681 0.511 rs881743 chr4:53727450 A/G cg00791764 chr4:53727839 RASL11B 0.45 4.45 0.37 1.91e-5 Optic nerve measurement (cup area); TGCT cis rs2862064 1.000 rs9313400 chr5:156433341 A/G cg12943317 chr5:156479607 HAVCR1 -0.45 -5.77 -0.46 5.83e-8 Platelet count; TGCT cis rs13082711 0.640 rs66941564 chr3:27259702 C/A cg02860705 chr3:27208620 NA 0.46 7.22 0.54 4.63e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2439831 0.850 rs2228368 chr15:44102010 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.69 4.53 0.38 1.38e-5 Lung cancer in ever smokers; TGCT trans rs10435719 0.902 rs7459545 chr8:11804389 G/T cg15556689 chr8:8085844 FLJ10661 0.76 7.28 0.55 3.36e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs10170846 0.861 rs6740452 chr2:223518452 C/T cg25565276 chr2:223520875 FARSB 0.55 4.58 0.38 1.11e-5 Schizophrenia (inflammation and infection response interaction); TGCT trans rs1499614 1.000 rs1882655 chr7:66147057 T/C cg07424592 chr7:64974309 NA -1.35 -8.11 -0.59 4.14e-13 Gout; TGCT cis rs2204008 0.748 rs11514352 chr12:38246954 C/T cg13010199 chr12:38710504 ALG10B 0.64 5.01 0.41 1.85e-6 Bladder cancer; TGCT cis rs2204008 0.527 rs1315367 chr12:38177487 G/T cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs912057 0.965 rs1294415 chr6:6740633 G/A cg06612196 chr6:6737390 NA 0.38 4.81 0.4 4.25e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs4711336 0.967 rs4711338 chr6:33660188 T/C cg14003231 chr6:33640908 ITPR3 0.28 4.52 0.38 1.41e-5 Height; TGCT cis rs13191362 1.000 rs67094146 chr6:163145412 G/C cg21926612 chr6:163149169 PACRG;PARK2 1.18 9.34 0.64 5.08e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2836950 0.565 rs7278297 chr21:40625752 A/C cg17971929 chr21:40555470 PSMG1 -0.54 -4.92 -0.4 2.71e-6 Menarche (age at onset); TGCT cis rs2832191 0.655 rs2247110 chr21:30323888 G/A cg24692254 chr21:30365293 RNF160 -0.95 -10.73 -0.69 2.09e-19 Dental caries; TGCT cis rs9916302 0.808 rs12947281 chr17:37652210 G/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg10862848 chr6:42927986 GNMT -0.4 -4.98 -0.41 2.11e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs11696501 0.591 rs6065854 chr20:44288816 T/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs58688157 0.960 rs702966 chr11:611919 C/G cg16486109 chr11:613632 IRF7 0.35 5.18 0.42 8.82e-7 Systemic lupus erythematosus; TGCT cis rs78456975 0.527 rs11886696 chr2:1567841 A/G cg12573674 chr2:1569213 NA -0.48 -5.1 -0.42 1.25e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs813218 0.523 rs1711554 chr3:99428998 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.12 0.42 1.13e-6 Orofacial clefts; TGCT cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs36051895 0.664 rs3780370 chr9:5095167 A/C cg02405213 chr9:5042618 JAK2 -0.72 -9.4 -0.65 3.59e-16 Pediatric autoimmune diseases; TGCT cis rs4499344 0.633 rs259256 chr19:33151802 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs7246657 0.722 rs1975937 chr19:38091932 A/T cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.71e-6 Coronary artery calcification; TGCT cis rs7191439 0.584 rs8048897 chr16:88744470 T/G cg27087555 chr16:88793112 FAM38A -0.47 -4.72 -0.39 6.27e-6 Plateletcrit; TGCT cis rs1150668 0.768 rs1233713 chr6:28198281 A/G cg11262757 chr6:27280423 POM121L2 0.45 4.44 0.37 1.94e-5 Pubertal anthropometrics; TGCT cis rs6570726 0.764 rs367065 chr6:145882309 T/G cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7584330 0.697 rs9287620 chr2:238368730 C/T cg08992911 chr2:238395768 MLPH 0.61 4.7 0.39 6.79e-6 Prostate cancer; TGCT cis rs9858542 1.000 rs9823546 chr3:49705512 T/A cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg05985448 chr10:134359359 INPP5A 0.21 4.74 0.39 5.74e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs185694 1.000 rs202082 chr13:30881026 G/A cg07600127 chr13:30881527 KATNAL1 -0.87 -6.77 -0.52 4.55e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs12765878 0.812 rs10786776 chr10:105662994 A/G cg11005552 chr10:105648138 OBFC1 -0.44 -7.29 -0.55 3.12e-11 Coronary artery disease; TGCT cis rs3784262 0.739 rs1530293 chr15:58210398 G/A cg12031962 chr15:58353849 ALDH1A2 -0.53 -7.68 -0.57 4.11e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7681440 0.835 rs6839608 chr4:90805493 T/C cg20003494 chr4:90757398 SNCA -0.62 -5.94 -0.47 2.7e-8 Dementia with Lewy bodies; TGCT cis rs7584330 0.868 rs13386290 chr2:238393136 G/C cg14458575 chr2:238380390 NA 0.56 8.29 0.6 1.61e-13 Prostate cancer; TGCT cis rs9362426 1.000 rs9450662 chr6:88088593 A/C cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.19 0.42 8.5e-7 Depressive episodes in bipolar disorder; TGCT cis rs6500602 0.855 rs1139652 chr16:4476089 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.44 0.5 2.4e-9 Schizophrenia; TGCT cis rs2153535 0.601 rs9406160 chr6:8464907 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.42e-8 Motion sickness; TGCT cis rs72781680 1.000 rs72781632 chr2:24198342 A/C cg08917208 chr2:24149416 ATAD2B 0.84 5.13 0.42 1.1e-6 Lymphocyte counts; TGCT cis rs9527 0.518 rs11191487 chr10:104734623 A/G cg15744005 chr10:104629667 AS3MT -0.61 -4.76 -0.39 5.37e-6 Arsenic metabolism; TGCT cis rs7246657 0.722 rs11083432 chr19:38182633 A/G cg03611452 chr19:38183253 ZNF781 -0.6 -5.16 -0.42 9.49e-7 Coronary artery calcification; TGCT cis rs9372253 1.000 rs9372253 chr6:110716136 C/T cg01119278 chr6:110721349 DDO -0.35 -5.68 -0.45 9e-8 Platelet distribution width; TGCT cis rs7249142 0.562 rs2314035 chr19:19284920 T/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.33 -4.51 -0.38 1.48e-5 IgG glycosylation; TGCT cis rs12682352 0.652 rs3827806 chr8:8724276 C/T cg17143192 chr8:8559678 CLDN23 0.46 4.66 0.39 7.92e-6 Neuroticism; TGCT cis rs7572733 0.534 rs1436131 chr2:198731230 A/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.32e-6 Dermatomyositis; TGCT cis rs61931739 0.500 rs11053194 chr12:34440841 A/G cg06521331 chr12:34319734 NA -0.28 -4.51 -0.38 1.47e-5 Morning vs. evening chronotype; TGCT cis rs7172809 0.599 rs74026918 chr15:77762851 G/C cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs4689388 0.926 rs3821940 chr4:6286711 C/A cg14416269 chr4:6271139 WFS1 0.39 5.19 0.42 8.22e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4803468 1.000 rs4803469 chr19:41922775 A/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.71 -0.69 2.31e-19 Height; TGCT cis rs10114408 0.921 rs1890376 chr9:96661535 A/C cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg12310025 chr6:25882481 NA 0.54 4.65 0.39 8.23e-6 Intelligence (multi-trait analysis); TGCT cis rs67311347 0.605 rs1880762 chr3:40283215 A/G cg13683864 chr3:40499215 RPL14 -0.85 -7.24 -0.55 4.08e-11 Renal cell carcinoma; TGCT cis rs651907 0.935 rs2929922 chr3:101587934 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.46 4.79 0.4 4.6e-6 Colorectal cancer; TGCT cis rs6840360 0.571 rs2406976 chr4:152541056 G/C cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs4730430 0.537 rs6960599 chr7:110157254 T/C cg14239618 chr7:110281356 NA 0.26 5.45 0.44 2.63e-7 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3008870 0.785 rs10889651 chr1:67463513 A/T cg08660285 chr1:67390436 MIER1;WDR78 -0.83 -8.65 -0.61 2.21e-14 Lymphocyte percentage of white cells; TGCT cis rs11673344 0.523 rs2082010 chr19:37530776 A/G cg08039142 chr19:36980659 ZNF566 0.49 4.5 0.37 1.57e-5 Obesity-related traits; TGCT cis rs7523050 0.643 rs17621922 chr1:109404454 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.55 0.51 1.4e-9 Fat distribution (HIV); TGCT cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg05738196 chr6:26577821 NA 0.87 11.3 0.71 8.47e-21 Intelligence (multi-trait analysis); TGCT cis rs4730430 0.557 rs10953661 chr7:110135479 T/C cg14239618 chr7:110281356 NA 0.24 4.65 0.39 8.25e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6952808 0.531 rs3778998 chr7:2180753 C/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.31 -0.49 4.57e-9 Bipolar disorder and schizophrenia; TGCT cis rs9486719 1.000 rs2472884 chr6:96863965 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs899997 0.954 rs4887091 chr15:79043580 T/C cg00061860 chr15:78953028 NA -0.27 -4.67 -0.39 7.62e-6 Coronary artery disease or large artery stroke; TGCT cis rs9400467 0.506 rs12214933 chr6:111558006 A/G cg15721981 chr6:111408429 SLC16A10 0.72 4.66 0.39 8.09e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs12210905 0.688 rs12202956 chr6:27356476 T/C cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs3749237 1.000 rs11130214 chr3:49735746 C/G cg07636037 chr3:49044803 WDR6 -0.63 -5.61 -0.45 1.24e-7 Resting heart rate; TGCT cis rs11785400 0.701 rs9297967 chr8:143723002 A/C cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.7e-7 Schizophrenia; TGCT cis rs17376456 0.569 rs6556839 chr5:93206292 T/C cg25358565 chr5:93447407 FAM172A -0.8 -6.09 -0.48 1.31e-8 Diabetic retinopathy; TGCT cis rs2688608 0.592 rs11000758 chr10:75493610 A/T cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs7582180 0.629 rs4851298 chr2:100949827 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs6752107 1.000 rs6738490 chr2:234161583 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.86 0.4 3.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg24330042 chr22:24384159 GSTT1 -0.46 -4.56 -0.38 1.21e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9733 0.596 rs6661872 chr1:150628357 C/G cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs17253792 0.822 rs11546 chr14:56146357 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs7726839 0.540 rs11750321 chr5:599196 C/T cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs4654899 0.802 rs2167811 chr1:21194510 A/G cg01072550 chr1:21505969 NA 0.46 6.86 0.52 2.89e-10 Superior frontal gyrus grey matter volume; TGCT cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg06481639 chr22:41940642 POLR3H -0.76 -6.97 -0.53 1.65e-10 Vitiligo; TGCT cis rs6714710 0.603 rs12988571 chr2:98405695 C/T cg26665480 chr2:98280029 ACTR1B 0.66 6.31 0.49 4.56e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7091068 0.754 rs6583903 chr10:95422174 T/C cg20715218 chr10:95462985 C10orf4 0.55 5.16 0.42 9.49e-7 Urinary tract infection frequency; TGCT cis rs11785400 0.793 rs4336593 chr8:143739647 A/C cg10596483 chr8:143751796 JRK -0.56 -5.64 -0.45 1.11e-7 Schizophrenia; TGCT cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg13665807 chr20:60559372 TAF4 -0.54 -5.47 -0.44 2.39e-7 Body mass index; TGCT trans rs12599106 0.839 rs3853177 chr16:34498532 A/G cg07332563 chr6:291687 DUSP22 -0.66 -6.76 -0.52 4.88e-10 Menopause (age at onset); TGCT cis rs11190604 1.000 rs4919466 chr10:102241213 T/C cg23241863 chr10:102295624 HIF1AN 0.64 5.04 0.41 1.59e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.1 14.26 0.79 6.49e-28 Height; TGCT cis rs13191362 0.935 rs34009353 chr6:163007668 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9644630 0.804 rs11783263 chr8:19371674 C/G cg06699216 chr8:19333253 CSGALNACT1 -0.27 -4.72 -0.39 6.21e-6 Oropharynx cancer; TGCT cis rs7681440 0.904 rs7671549 chr4:90771147 T/A cg14346243 chr4:90757452 SNCA -0.57 -5.5 -0.44 2.04e-7 Dementia with Lewy bodies; TGCT cis rs7614311 0.681 rs3774708 chr3:63881549 A/C cg22134162 chr3:63841271 THOC7 -0.39 -5.15 -0.42 1e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs4654899 0.758 rs9426652 chr1:21458151 G/A cg01072550 chr1:21505969 NA -0.58 -9.57 -0.65 1.41e-16 Superior frontal gyrus grey matter volume; TGCT cis rs4319547 0.656 rs1553179 chr12:122831073 A/G cg08088222 chr12:122070432 ORAI1 0.26 4.66 0.39 8.01e-6 Body mass index; TGCT cis rs35306767 0.714 rs12762955 chr10:1078782 A/C cg26597838 chr10:835615 NA 0.52 5.98 0.47 2.22e-8 Eosinophil percentage of granulocytes; TGCT cis rs3782455 0.793 rs77365057 chr12:114404294 G/A cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs854765 0.718 rs12943500 chr17:17790588 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.45 -0.44 2.66e-7 Total body bone mineral density; TGCT cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.55 -6.53 -0.51 1.5e-9 Alzheimer's disease; TGCT cis rs6426558 0.537 rs498020 chr1:227304180 G/A cg10327440 chr1:227177885 CDC42BPA 0.58 6.91 0.53 2.21e-10 Neutrophil percentage of white cells; TGCT cis rs10875746 0.951 rs10875747 chr12:48525861 A/G cg20731937 chr12:48336164 NA 0.61 4.82 0.4 4.14e-6 Longevity (90 years and older); TGCT trans rs7615952 0.932 rs13325495 chr3:125637416 T/G cg07211511 chr3:129823064 LOC729375 -0.46 -6.73 -0.52 5.49e-10 Blood pressure (smoking interaction); TGCT cis rs7937612 1.000 rs7924963 chr11:120233536 G/A cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.62 -0.38 9.5e-6 Intraocular pressure; TGCT cis rs4891159 0.790 rs17059325 chr18:74119567 A/C cg24786174 chr18:74118243 ZNF516 -0.57 -7.72 -0.57 3.3e-12 Longevity; TGCT cis rs4925386 0.681 rs2427295 chr20:60927431 G/A cg24112000 chr20:60950667 NA -0.37 -4.45 -0.37 1.9e-5 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs6964587 0.692 rs6953256 chr7:91575417 C/T cg17063962 chr7:91808500 NA -0.75 -7.1 -0.54 8.63e-11 Breast cancer; TGCT cis rs16966142 1.000 rs16966142 chr16:89851033 C/T cg04287289 chr16:89883240 FANCA 0.95 5.33 0.43 4.49e-7 Caffeine consumption; TGCT cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg10295955 chr4:187884368 NA -1.02 -15.6 -0.81 5.02e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs2258769 chr20:25276680 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9527 0.545 rs7915816 chr10:104881750 A/G cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs7666738 0.830 rs13148913 chr4:99009732 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg27535305 chr1:53392650 SCP2 -0.25 -5.06 -0.41 1.47e-6 Monocyte count; TGCT cis rs4808199 0.948 rs757001 chr19:19448808 G/A cg03709012 chr19:19516395 GATAD2A 0.81 6.32 0.49 4.32e-9 Nonalcoholic fatty liver disease; TGCT cis rs7267979 0.714 rs6132825 chr20:25238309 A/T cg14121845 chr20:25566513 NINL 0.46 4.57 0.38 1.17e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs60843830 1.000 rs62114548 chr2:274672 C/G cg00108164 chr2:264199 ACP1;SH3YL1 0.7 6.56 0.51 1.33e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs16958440 0.867 rs80064497 chr18:44669653 A/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs1018836 0.608 rs1033348 chr8:91464169 C/G cg16814680 chr8:91681699 NA -0.71 -7.27 -0.55 3.49e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9325144 0.555 rs4550281 chr12:38689937 A/G cg26384229 chr12:38710491 ALG10B 0.66 6.13 0.48 1.09e-8 Morning vs. evening chronotype; TGCT cis rs3793683 0.965 rs3829131 chr10:134564627 A/G cg27286337 chr10:134555280 INPP5A -0.46 -7.05 -0.53 1.1e-10 Migraine; TGCT trans rs7819412 0.749 rs11991118 chr8:10939273 A/C cg15556689 chr8:8085844 FLJ10661 0.69 6.63 0.51 9.08e-10 Triglycerides; TGCT cis rs12615966 1.000 rs72830442 chr2:105375329 G/C cg16465502 chr2:105461796 NA 0.81 4.47 0.37 1.76e-5 Pancreatic cancer; TGCT cis rs2239815 0.576 rs10427628 chr22:29239766 T/C cg02153584 chr22:29168773 CCDC117 0.6 4.53 0.38 1.38e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs7666738 0.830 rs17484966 chr4:99014432 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.28 0.43 5.54e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg10802521 chr3:52805072 NEK4 -0.74 -9.02 -0.63 2.87e-15 Bipolar disorder; TGCT trans rs7618501 1.000 rs7431106 chr3:49808374 G/A cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs9322193 0.923 rs9800736 chr6:149982417 A/G cg13206674 chr6:150067644 NUP43 0.53 4.56 0.38 1.23e-5 Lung cancer; TGCT cis rs72781680 0.898 rs79023848 chr2:24038174 C/A cg08917208 chr2:24149416 ATAD2B 0.92 5.75 0.46 6.55e-8 Lymphocyte counts; TGCT cis rs2153535 0.580 rs9392223 chr6:8468650 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.12 0.42 1.12e-6 Motion sickness; TGCT cis rs1981331 0.609 rs59121565 chr21:48043023 A/G cg23283320 chr21:48055893 PRMT2 1.35 6.43 0.5 2.51e-9 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs7929679 0.875 rs2217480 chr11:34811928 G/A cg18414381 chr11:34642885 EHF -0.23 -4.51 -0.38 1.47e-5 Chronic obstructive pulmonary disease-related biomarkers;Lung disease severity in cystic fibrosis; TGCT cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs7681440 0.904 rs35424815 chr4:90767877 C/T cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs7809950 1.000 rs2057837 chr7:107222725 C/G cg23024343 chr7:107201750 COG5 0.33 5.07 0.41 1.42e-6 Coronary artery disease; TGCT cis rs9372498 0.536 rs62422228 chr6:118957276 T/C cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs6951245 0.554 rs4724294 chr7:1139695 G/A cg03188948 chr7:1209495 NA 0.52 5.4 0.44 3.29e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs904251 0.600 rs2270687 chr6:37418263 A/G cg25019722 chr6:37503610 NA -0.48 -6.98 -0.53 1.57e-10 Cognitive performance; TGCT cis rs57994353 0.865 rs13290734 chr9:139330701 G/A cg13741927 chr9:139327495 INPP5E -0.27 -6.41 -0.5 2.72e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2594989 0.721 rs9860504 chr3:11573615 G/T cg26283222 chr3:11613257 VGLL4 0.2 4.45 0.37 1.89e-5 Circulating chemerin levels; TGCT cis rs7726839 0.540 rs61731455 chr5:665295 A/G cg20362242 chr5:692897 TPPP 0.51 4.66 0.39 8.11e-6 Obesity-related traits; TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg01802117 chr1:53393560 SCP2 -0.39 -4.61 -0.38 1e-5 Monocyte count; TGCT cis rs7666738 0.830 rs1426662 chr4:98990319 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.816 rs6138593 chr20:25504492 A/G cg03522245 chr20:25566470 NINL 0.56 5.79 0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs933688 1.000 rs60513756 chr5:90727692 A/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 8.73 0.62 1.47e-14 Smoking behavior; TGCT cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg06035815 chr6:26189597 HIST1H4D 0.44 4.52 0.38 1.41e-5 Schizophrenia; TGCT cis rs7267979 0.866 rs2424698 chr20:25256106 C/T cg14121845 chr20:25566513 NINL 0.53 5.88 0.47 3.57e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6089584 0.706 rs6089625 chr20:60620622 T/C cg06108461 chr20:60628389 TAF4 -0.69 -10.64 -0.69 3.59e-19 Body mass index; TGCT cis rs4074961 0.527 rs10908355 chr1:38035286 G/T cg11397548 chr1:38022522 DNALI1 0.42 4.95 0.41 2.39e-6 Axial length; TGCT cis rs7698623 0.850 rs4147244 chr4:88779168 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs514406 0.505 rs269287 chr1:53168842 T/C cg16325326 chr1:53192061 ZYG11B 0.85 11.49 0.72 2.95e-21 Monocyte count; TGCT cis rs7267979 1.000 rs6050599 chr20:25400240 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs938554 0.513 rs10939650 chr4:9998440 C/T cg02734326 chr4:10020555 SLC2A9 0.48 4.85 0.4 3.6e-6 Blood metabolite levels; TGCT cis rs9300255 0.639 rs1716171 chr12:123716376 C/T cg00376283 chr12:123451042 ABCB9 0.67 5.26 0.43 6.13e-7 Neutrophil percentage of white cells; TGCT cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg04025307 chr7:1156635 C7orf50 0.24 5.78 0.46 5.71e-8 Longevity;Endometriosis; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg12419862 chr22:24373484 LOC391322 -0.84 -9.57 -0.65 1.36e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1153858 0.621 rs2413769 chr15:45561868 A/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.09 0.42 1.32e-6 Homoarginine levels; TGCT cis rs6089829 0.888 rs4809465 chr20:61671156 G/C cg02380750 chr20:61661411 NA 0.35 5.68 0.45 9.19e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg24503407 chr1:205819492 PM20D1 0.57 7.77 0.57 2.53e-12 Menarche (age at onset); TGCT cis rs34891900 0.507 rs2535707 chr22:18181869 C/T cg19898043 chr22:18121309 BCL2L13 -0.56 -4.76 -0.39 5.31e-6 Sum neutrophil eosinophil counts; TGCT cis rs208520 0.874 rs208518 chr6:66948501 C/G cg07460842 chr6:66804631 NA 0.91 9.18 0.64 1.21e-15 Exhaled nitric oxide output; TGCT cis rs9650657 0.529 rs10108618 chr8:10953092 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.56 -0.38 1.21e-5 Neuroticism; TGCT cis rs7959452 0.535 rs1350166 chr12:69636314 G/T cg20891283 chr12:69753455 YEATS4 0.65 6.32 0.49 4.36e-9 Blood protein levels; TGCT cis rs4253772 0.591 rs9615935 chr22:46686115 T/G cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs4727027 0.745 rs10952801 chr7:148864757 T/C cg23583168 chr7:148888333 NA -0.76 -10.09 -0.67 7.46e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs116095464 0.558 rs9312978 chr5:221930 C/G cg12570787 chr5:219185 SDHA;CCDC127 0.71 4.75 0.39 5.44e-6 Breast cancer; TGCT cis rs854765 0.647 rs6502637 chr17:17986098 A/G cg04398451 chr17:18023971 MYO15A -0.37 -6.51 -0.5 1.71e-9 Total body bone mineral density; TGCT cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs7582180 0.764 rs11691684 chr2:100921776 T/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs2180341 1.000 rs2144742 chr6:127595786 C/A cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs7208859 0.623 rs56812022 chr17:29068733 A/G cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7085104 0.513 rs192569 chr10:104577915 T/C cg05855489 chr10:104503620 C10orf26 -0.59 -5.61 -0.45 1.24e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs6088590 1.000 rs2295354 chr20:33356541 T/C cg24642439 chr20:33292090 TP53INP2 0.7 6.22 0.49 7.12e-9 Coronary artery disease; TGCT cis rs11031096 0.803 rs11031142 chr11:4174375 C/T cg18678763 chr11:4115507 RRM1 0.39 5.24 0.43 6.69e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs3791556 1.000 rs3791562 chr2:240113436 C/T cg03281426 chr2:240109471 HDAC4 0.28 4.46 0.37 1.82e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT trans rs916888 0.779 rs430685 chr17:44859148 T/C cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11030122 0.702 rs10835311 chr11:3949027 G/T cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs9467773 0.836 rs1624440 chr6:26433329 G/A cg15659132 chr6:26577336 NA -0.55 -5.77 -0.46 5.89e-8 Intelligence (multi-trait analysis); TGCT cis rs1372520 0.684 rs2619368 chr4:90729747 T/G cg14346243 chr4:90757452 SNCA -0.68 -5.64 -0.45 1.12e-7 Neuroticism; TGCT cis rs6088580 0.634 rs6120644 chr20:33023810 G/A cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs7772486 0.754 rs9399561 chr6:145955687 C/G cg23711669 chr6:146136114 FBXO30 0.92 10.45 0.68 1.03e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs11030122 0.673 rs11030639 chr11:4039056 A/G cg18678763 chr11:4115507 RRM1 -0.48 -5.96 -0.47 2.39e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs734999 0.524 rs4648448 chr1:2695687 C/T cg18854424 chr1:2615690 NA 0.45 5.01 0.41 1.82e-6 Ulcerative colitis; TGCT cis rs9534288 0.731 rs7981685 chr13:46605495 G/A cg15192986 chr13:46630673 CPB2 -0.52 -7.5 -0.56 1.06e-11 Blood protein levels; TGCT cis rs6426558 0.537 rs7523167 chr1:227365304 G/A cg10327440 chr1:227177885 CDC42BPA -0.6 -6.95 -0.53 1.84e-10 Neutrophil percentage of white cells; TGCT cis rs473651 0.692 rs579511 chr2:239334914 C/G cg18131467 chr2:239335373 ASB1 0.99 13.74 0.78 1.09e-26 Multiple system atrophy; TGCT cis rs10504229 0.638 rs7826839 chr8:58132075 G/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs12497850 0.931 rs9867373 chr3:48960938 A/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs7267979 1.000 rs6050564 chr20:25344231 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2180341 1.000 rs3798852 chr6:127636733 A/G cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7605378 1.000 rs769954 chr2:200692159 C/G cg23649088 chr2:200775458 C2orf69 -0.34 -5.63 -0.45 1.12e-7 Osteoporosis; TGCT cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -8.51 -0.61 4.86e-14 Platelet count; TGCT cis rs9389248 0.728 rs1022491 chr6:135259366 C/T cg24558204 chr6:135376177 HBS1L -0.51 -5.11 -0.42 1.21e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs9788682 0.747 rs3743078 chr15:78894759 C/G cg24631222 chr15:78858424 CHRNA5 -0.79 -5.84 -0.46 4.39e-8 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7959452 0.719 rs57954211 chr12:69748397 C/A cg14784868 chr12:69753453 YEATS4 0.85 9.43 0.65 3.01e-16 Blood protein levels; TGCT cis rs3824867 0.920 rs7948705 chr11:47447955 C/G cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs2721173 0.619 rs997258 chr8:145903077 C/A cg17328964 chr8:145687451 CYHR1 0.44 5.83 0.46 4.54e-8 Educational attainment;Cognitive ability (multi-trait analysis);Intelligence (multi-trait analysis); TGCT cis rs651907 0.535 rs17347156 chr3:101504674 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.15 0.67 5.47e-18 Colorectal cancer; TGCT cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.53 0.56 9.26e-12 Platelet count; TGCT cis rs7523273 0.927 rs2796275 chr1:207950490 C/T cg22525895 chr1:207977042 MIR29B2 0.48 8.31 0.6 1.42e-13 Schizophrenia; TGCT cis rs3733585 0.673 rs4560411 chr4:9953361 A/G cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg21724239 chr8:58056113 NA 0.46 5.0 0.41 1.89e-6 Developmental language disorder (linguistic errors); TGCT cis rs1185460 0.967 rs11217133 chr11:118928249 G/A cg01677386 chr11:118938358 VPS11 -0.55 -4.61 -0.38 9.95e-6 Coronary artery disease; TGCT cis rs6570726 0.935 rs380883 chr6:145822992 A/G cg23711669 chr6:146136114 FBXO30 0.71 6.77 0.52 4.64e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 0.727 rs11161626 chr1:76260837 C/T cg03433033 chr1:76189801 ACADM 0.64 6.5 0.5 1.75e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs8180040 0.726 rs11130112 chr3:47024495 G/T cg27129171 chr3:47204927 SETD2 0.75 9.49 0.65 2.15e-16 Colorectal cancer; TGCT cis rs904251 0.504 rs2797795 chr6:37480683 T/C cg08126542 chr6:37504118 NA -0.44 -6.51 -0.5 1.71e-9 Cognitive performance; TGCT cis rs5769765 0.913 rs8135071 chr22:50299587 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.21 0.42 7.51e-7 Schizophrenia; TGCT cis rs11792861 0.926 rs56899598 chr9:111867271 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.48 0.37 1.66e-5 Menarche (age at onset); TGCT cis rs6910741 0.641 rs1892247 chr6:25887657 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.76 5.22 0.42 7.19e-7 Blood pressure; TGCT trans rs9929218 0.529 rs11075694 chr16:68730366 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.54 6.75 0.52 4.98e-10 Colorectal cancer; TGCT cis rs9549260 0.564 rs9315784 chr13:41289166 G/A cg21288729 chr13:41239152 FOXO1 0.87 7.86 0.58 1.59e-12 Red blood cell count; TGCT cis rs5769707 0.632 rs1476037 chr22:49991377 G/A cg05373962 chr22:49881684 NA -0.3 -5.14 -0.42 1.04e-6 Monocyte count;Monocyte percentage of white cells; TGCT trans rs916888 0.821 rs70602 chr17:44859715 T/C cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg07157834 chr1:205819609 PM20D1 0.51 8.84 0.62 7.96e-15 Menarche (age at onset); TGCT cis rs983545 0.573 rs9872060 chr3:16920117 A/G cg21767191 chr3:17082105 PLCL2 0.22 4.5 0.37 1.52e-5 Blood protein levels; TGCT cis rs6450176 0.625 rs3776725 chr5:53290138 C/A ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.58 -0.45 1.45e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7954584 0.567 rs11043233 chr12:122330733 C/T cg21171335 chr12:122356390 WDR66 0.66 6.65 0.51 8.56e-10 Mean corpuscular volume; TGCT cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.7e-7 Developmental language disorder (linguistic errors); TGCT cis rs6519955 0.866 rs9626920 chr22:46428993 A/G cg05468064 chr22:46423449 NA -0.56 -5.87 -0.47 3.67e-8 Dupuytren's disease; TGCT cis rs1862618 0.525 rs2662016 chr5:56269047 A/G cg20203395 chr5:56204925 C5orf35 0.59 4.5 0.37 1.57e-5 Initial pursuit acceleration; TGCT cis rs17376456 0.877 rs9314099 chr5:93447375 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs589448 0.933 rs2249093 chr12:69753512 G/C cg14784868 chr12:69753453 YEATS4 0.9 10.55 0.69 5.67e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs7829975 0.653 rs13259070 chr8:8690787 C/T cg15556689 chr8:8085844 FLJ10661 0.69 6.15 0.48 9.66e-9 Mood instability; TGCT cis rs854765 0.583 rs7222480 chr17:17818817 G/T cg09796270 chr17:17721594 SREBF1 0.27 5.55 0.45 1.69e-7 Total body bone mineral density; TGCT cis rs6450176 1.000 rs7735253 chr5:53297611 G/A ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.12 -0.42 1.15e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT trans rs2727020 0.521 rs7126835 chr11:49594658 T/C cg11707556 chr5:10655725 ANKRD33B -0.4 -7.69 -0.57 3.92e-12 Coronary artery disease; TGCT cis rs6722750 0.782 rs7608530 chr2:64412043 T/A cg22352474 chr2:64371530 PELI1 -0.57 -4.94 -0.41 2.52e-6 Neuroticism; TGCT cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg08392591 chr16:89556376 ANKRD11 0.58 5.26 0.43 6.25e-7 Multiple myeloma (IgH translocation); TGCT cis rs1635 0.655 rs16893973 chr6:28302113 C/T cg15743358 chr6:28303923 ZNF323 -1.27 -6.2 -0.49 7.86e-9 Schizophrenia; TGCT cis rs7772486 0.790 rs2485632 chr6:146193228 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.46 -0.37 1.83e-5 Lobe attachment (rater-scored or self-reported); TGCT trans rs4650994 0.507 rs12141152 chr1:178514165 C/T cg05059571 chr16:84539110 KIAA1609 -0.54 -11.05 -0.7 3.43e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs933688 1.000 rs10045280 chr5:90717675 T/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 9.38 0.64 4.06e-16 Smoking behavior; TGCT cis rs7923609 1.000 rs12355784 chr10:65121565 G/T cg08743896 chr10:65200160 JMJD1C -0.34 -4.61 -0.38 9.73e-6 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs12142240 0.583 rs5013330 chr1:46815154 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7172809 0.599 rs116981387 chr15:77753231 G/A cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT trans rs4650994 0.544 rs2811314 chr1:178619183 C/T cg05059571 chr16:84539110 KIAA1609 0.51 9.71 0.66 6.42e-17 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6088590 0.561 rs3891369 chr20:33161127 C/T cg06115741 chr20:33292138 TP53INP2 0.54 4.72 0.39 6.32e-6 Coronary artery disease; TGCT cis rs1153858 1.000 rs2467863 chr15:45641880 G/A cg26924012 chr15:45694286 SPATA5L1 1.05 13.63 0.77 2.04e-26 Homoarginine levels; TGCT trans rs6089829 1.000 rs62207535 chr20:61669187 A/G cg23505145 chr19:12996616 KLF1 0.89 9.92 0.67 1.94e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs12477438 0.520 rs36071868 chr2:99737120 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.26 0.77 1.59e-25 Chronic sinus infection; TGCT cis rs28595532 0.920 rs116047800 chr4:119773569 G/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs4919669 0.777 rs10883766 chr10:104464763 G/A cg05855489 chr10:104503620 C10orf26 0.73 4.45 0.37 1.91e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs4332037 0.539 rs11764780 chr7:2020904 G/C cg25834613 chr7:1915315 MAD1L1 -0.47 -4.51 -0.38 1.48e-5 Bipolar disorder; TGCT cis rs57221529 0.766 rs12519469 chr5:581772 A/G cg20362242 chr5:692897 TPPP 0.49 4.7 0.39 6.76e-6 Lung disease severity in cystic fibrosis; TGCT trans rs941408 1.000 rs1624295 chr19:2792034 G/A cg22153745 chr1:153894579 GATAD2B -0.65 -7.5 -0.56 1.08e-11 Total cholesterol levels; TGCT cis rs7412746 0.611 rs12410869 chr1:150856153 G/T cg09365446 chr1:150670422 GOLPH3L 0.35 5.0 0.41 1.87e-6 Melanoma; TGCT cis rs77686669 1 rs77686669 chr7:99744572 T/C cg13334819 chr7:99746414 C7orf59 0.54 4.57 0.38 1.16e-5 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs1367858 0.661 rs3856513 chr2:201234216 G/A cg04283868 chr2:201171347 SPATS2L 0.52 4.96 0.41 2.32e-6 Schizophrenia; TGCT cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.23e-17 Electroencephalogram traits; TGCT cis rs9682041 0.696 rs9872796 chr3:170099393 T/G cg07589077 chr3:170072950 NA 0.31 4.7 0.39 6.94e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT trans rs62103177 0.733 rs62096748 chr18:77619699 T/C cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs7833790 0.963 rs72686466 chr8:82758928 G/T cg17211192 chr8:82754475 SNX16 1.06 8.51 0.61 4.89e-14 Diastolic blood pressure; TGCT cis rs9911578 1.000 rs9892795 chr17:57023054 G/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs4237845 0.837 rs7971877 chr12:58287630 T/G cg02175503 chr12:58329896 NA 0.49 5.01 0.41 1.85e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.546 rs10018080 chr4:98758436 C/A cg18180107 chr4:99064573 C4orf37 0.54 4.78 0.39 4.93e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg25703541 chr22:24373054 LOC391322 -0.85 -9.07 -0.63 2.28e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1857353 1.000 rs74089238 chr1:75888220 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs1448094 0.556 rs61930626 chr12:86167445 A/G cg02569458 chr12:86230093 RASSF9 0.38 4.49 0.37 1.61e-5 Major depressive disorder; TGCT cis rs928736 0.599 rs1000005 chr21:34433051 C/G cg04836472 chr21:34405997 NA 0.48 5.96 0.47 2.46e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7043114 0.525 rs2274966 chr9:95155563 C/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.59 -0.45 1.36e-7 Height; TGCT cis rs4925386 1.000 rs6089351 chr20:60916153 G/A cg06026331 chr20:60912101 LAMA5 -0.29 -5.44 -0.44 2.74e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs5769765 0.773 rs9616208 chr22:50313359 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.42 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs10504229 0.636 rs72649123 chr8:58045789 A/T cg20607798 chr8:58055168 NA 0.45 4.68 0.39 7.52e-6 Developmental language disorder (linguistic errors); TGCT cis rs1008375 0.932 rs1008894 chr4:17704667 C/T cg18681998 chr4:17616180 MED28 -0.8 -7.85 -0.58 1.68e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg26531700 chr6:26746687 NA 0.51 4.71 0.39 6.4e-6 Intelligence (multi-trait analysis); TGCT trans rs804280 0.535 rs10435719 chr8:11776904 C/T cg15556689 chr8:8085844 FLJ10661 0.8 7.46 0.56 1.34e-11 Myopia (pathological); TGCT cis rs4665809 0.618 rs7579199 chr2:26266496 G/A cg04944784 chr2:26401820 FAM59B -0.68 -6.07 -0.48 1.45e-8 Gut microbiome composition (summer); TGCT cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28595532 0.920 rs115118317 chr4:119736613 C/T cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.53 4.55 0.38 1.26e-5 Cerebrospinal P-tau181p levels; TGCT cis rs9818758 0.607 rs11710247 chr3:49249800 G/T cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs57221529 0.600 rs11750269 chr5:666270 G/A cg16624210 chr5:671434 TPPP 0.43 4.98 0.41 2.11e-6 Lung disease severity in cystic fibrosis; TGCT cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs10114408 0.959 rs10761299 chr9:96649537 T/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs344364 0.511 rs62040569 chr16:1948137 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs12477438 0.715 rs6724476 chr2:99627316 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs10782582 0.586 rs5745383 chr1:76288590 G/C cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs3540 0.533 rs12708585 chr15:91052285 C/T cg22089800 chr15:90895588 ZNF774 -0.76 -7.83 -0.58 1.83e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg23205692 chr1:25664452 TMEM50A 0.5 5.21 0.42 7.56e-7 Erythrocyte sedimentation rate; TGCT cis rs10871290 0.881 rs7498574 chr16:74472661 A/G cg01733217 chr16:74700730 RFWD3 -0.6 -5.66 -0.45 1.02e-7 Breast cancer; TGCT cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg11502198 chr6:26597334 ABT1 0.53 4.9 0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.606 rs11776838 chr8:8794801 C/T cg15556689 chr8:8085844 FLJ10661 -0.67 -6.02 -0.48 1.84e-8 Mood instability; TGCT cis rs6570726 1.000 rs441477 chr6:145848243 C/T cg23711669 chr6:146136114 FBXO30 0.69 6.5 0.5 1.78e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg23172400 chr8:95962367 TP53INP1 -0.37 -6.1 -0.48 1.27e-8 Type 2 diabetes; TGCT cis rs9611565 0.729 rs137831 chr22:41903813 A/C cg02107564 chr22:41488750 EP300 -0.56 -4.55 -0.38 1.28e-5 Vitiligo; TGCT cis rs7937682 0.632 rs4935811 chr11:111679262 C/T cg09085632 chr11:111637200 PPP2R1B 0.81 7.16 0.54 6.29e-11 Primary sclerosing cholangitis; TGCT cis rs10744422 0.764 rs4307760 chr12:123293048 C/G cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs1670533 1.000 rs6852558 chr4:1059944 C/T cg20887711 chr4:1340912 KIAA1530 0.65 5.14 0.42 1.05e-6 Recombination rate (females); TGCT cis rs4845570 1.000 rs11585294 chr1:151769887 A/C cg07092448 chr1:151763213 TDRKH -1.12 -8.62 -0.61 2.64e-14 Coronary artery disease; TGCT trans rs1005277 0.579 rs2472174 chr10:38375382 A/G cg17830980 chr10:43048298 ZNF37B -0.87 -11.04 -0.7 3.63e-20 Extrinsic epigenetic age acceleration; TGCT cis rs2120019 0.638 rs12050628 chr15:75333494 G/A cg09165964 chr15:75287851 SCAMP5 1.13 11.66 0.72 1.13e-21 Blood trace element (Zn levels); TGCT cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg21171335 chr12:122356390 WDR66 0.48 4.86 0.4 3.55e-6 Mean corpuscular volume; TGCT cis rs78487399 0.908 rs12474102 chr2:43835570 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.68 4.85 0.4 3.7e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs28735056 0.584 rs11664834 chr18:77644876 G/T cg20368463 chr18:77673604 PQLC1 0.47 5.4 0.44 3.26e-7 Schizophrenia; TGCT cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg02458000 chr6:26745757 NA 0.52 4.8 0.4 4.48e-6 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.900 rs6740838 chr2:100813499 T/G cg07810366 chr2:100720526 AFF3 -0.4 -6.09 -0.48 1.3e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs1794164 chr11:49899610 T/C cg03929089 chr4:120376271 NA -0.71 -8.06 -0.59 5.34e-13 Height; TGCT cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg06238570 chr21:40685208 BRWD1 0.81 8.67 0.61 2e-14 Cognitive function; TGCT cis rs4699052 0.662 rs6848091 chr4:104250101 A/G cg16532752 chr4:104119610 CENPE -0.49 -4.89 -0.4 3.07e-6 Testicular germ cell tumor; TGCT cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg06896619 chr17:61851486 DDX42;CCDC47 0.49 4.83 0.4 4e-6 Prudent dietary pattern; TGCT cis rs4851266 1.000 rs11689201 chr2:100820431 A/G cg22139774 chr2:100720529 AFF3 -0.35 -5.23 -0.43 6.83e-7 Educational attainment; TGCT cis rs7267979 0.966 rs2482923 chr20:25308981 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg15659132 chr6:26577336 NA 0.86 10.81 0.7 1.36e-19 Intelligence (multi-trait analysis); TGCT trans rs8073060 0.614 rs225275 chr17:33972567 G/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs595982 0.559 rs17272680 chr19:49364511 A/G cg15549821 chr19:49342101 PLEKHA4 0.69 9.3 0.64 6.08e-16 Red cell distribution width; TGCT cis rs7659604 1.000 rs6814995 chr4:122664963 A/T cg19748678 chr4:122722346 EXOSC9 -0.55 -5.3 -0.43 5.2e-7 Type 2 diabetes; TGCT cis rs2204008 0.623 rs4882302 chr12:38415608 T/A cg26384229 chr12:38710491 ALG10B -0.53 -4.64 -0.38 8.67e-6 Bladder cancer; TGCT cis rs2721195 0.967 rs11777703 chr8:145703508 G/A cg15320075 chr8:145703422 NA -0.72 -7.46 -0.56 1.32e-11 Age at first birth; TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg10108389 chr3:44770937 ZNF501 -0.47 -4.87 -0.4 3.34e-6 Depressive symptoms; TGCT cis rs4953076 0.573 rs67537903 chr2:44422111 G/A cg00619915 chr2:44497795 NA -0.23 -5.14 -0.42 1.02e-6 Height; TGCT cis rs2204008 0.641 rs66876045 chr12:38205713 G/A cg13010199 chr12:38710504 ALG10B 0.62 4.89 0.4 3.09e-6 Bladder cancer; TGCT cis rs11098499 0.604 rs2389886 chr4:120570422 C/T cg09307838 chr4:120376055 NA 0.65 6.32 0.49 4.22e-9 Corneal astigmatism; TGCT cis rs2692947 0.726 rs13019188 chr2:96774199 A/G cg23100626 chr2:96804247 ASTL -0.39 -4.67 -0.39 7.56e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs921968 0.643 rs2243911 chr2:219529348 C/T cg02176678 chr2:219576539 TTLL4 -0.38 -5.47 -0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT trans rs561341 1.000 rs7216102 chr17:30259450 A/G cg20587970 chr11:113659929 NA -0.93 -10.95 -0.7 6.29e-20 Hip circumference adjusted for BMI; TGCT cis rs922182 0.557 rs8039736 chr15:64188251 G/A cg02919090 chr15:64263738 DAPK2 0.31 5.6 0.45 1.33e-7 Blood protein levels; TGCT cis rs561341 0.769 rs9899093 chr17:30191954 C/G cg08728848 chr17:30437958 NA 0.3 4.79 0.4 4.68e-6 Hip circumference adjusted for BMI; TGCT cis rs7258465 0.965 rs7254249 chr19:18591745 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs1775715 0.966 rs1251386 chr10:32319114 C/T cg14930904 chr10:32216787 ARHGAP12 -0.5 -4.63 -0.38 8.96e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.19 0.42 8.48e-7 Menopause (age at onset); TGCT cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg07061783 chr6:25882402 NA 0.51 5.57 0.45 1.51e-7 Blood metabolite levels; TGCT cis rs17221829 0.965 rs28614109 chr11:89460943 A/G cg02982614 chr11:89391479 FOLH1B -0.3 -5.15 -0.42 9.89e-7 Anxiety in major depressive disorder; TGCT cis rs1371867 0.846 rs1660317 chr8:101333252 G/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs7193541 0.684 rs8062783 chr16:74691264 C/T cg01733217 chr16:74700730 RFWD3 -1.0 -13.57 -0.77 2.84e-26 Multiple myeloma; TGCT cis rs1577917 0.740 rs2842604 chr6:86336300 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs826838 0.616 rs10880751 chr12:38627485 C/T cg26384229 chr12:38710491 ALG10B 0.51 4.54 0.38 1.3e-5 Heart rate; TGCT cis rs28595532 0.920 rs116697254 chr4:119733603 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs10504229 0.679 rs12675340 chr8:58035501 T/A cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT trans rs9388451 0.874 rs1159974 chr6:126090277 C/T cg05039488 chr6:79577232 IRAK1BP1 0.74 8.31 0.6 1.4e-13 Brugada syndrome; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs7586879 0.616 rs11900505 chr2:25131986 A/C cg15423357 chr2:25149977 NA 0.52 5.03 0.41 1.65e-6 Body mass index; TGCT cis rs12893668 0.667 rs71417869 chr14:104077434 A/G cg26031613 chr14:104095156 KLC1 -0.55 -4.54 -0.38 1.3e-5 Reticulocyte count; TGCT cis rs9295536 0.651 rs6921113 chr6:22136879 G/T cg25792714 chr6:21666554 FLJ22536 -0.52 -4.55 -0.38 1.27e-5 Neuroblastoma; TGCT cis rs9611565 1.000 rs9611565 chr22:41767486 T/C cg13695892 chr22:41940480 POLR3H -0.72 -6.9 -0.53 2.32e-10 Vitiligo; TGCT cis rs2120019 1.000 rs7168680 chr15:75369212 G/A cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs9513593 0.901 rs7330165 chr13:99889427 C/T cg21788972 chr13:99853209 UBAC2 -0.55 -4.46 -0.37 1.79e-5 Psoriasis; TGCT cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg00684032 chr4:1343700 KIAA1530 0.25 5.28 0.43 5.47e-7 Obesity-related traits; TGCT cis rs5750830 0.594 rs1010170 chr22:39778327 C/T cg02038168 chr22:39784481 NA 0.7 5.75 0.46 6.64e-8 Intelligence (multi-trait analysis); TGCT cis rs425277 0.959 rs77665022 chr1:2065958 C/T cg03732007 chr1:2071316 PRKCZ 0.25 5.01 0.41 1.81e-6 Height; TGCT cis rs9926296 0.632 rs7184315 chr16:89799373 C/G cg03388025 chr16:89894329 SPIRE2 -0.32 -4.77 -0.39 5.09e-6 Vitiligo; TGCT trans rs10802346 0.545 rs2362252 chr1:246371574 A/C cg13514129 chr1:39547527 MACF1 0.86 7.71 0.57 3.54e-12 Fractional exhaled nitric oxide (childhood); TGCT cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg00814883 chr7:100076585 TSC22D4 -0.89 -9.03 -0.63 2.76e-15 Platelet count; TGCT cis rs1008375 0.898 rs61047804 chr4:17593965 G/A cg10189774 chr4:17578691 LAP3 0.71 6.05 0.48 1.59e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7312933 0.531 rs2406674 chr12:42720150 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.7 -0.46 8.16e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10501293 0.917 rs10838003 chr11:43071988 T/A cg03447554 chr11:43094025 NA 0.44 6.52 0.51 1.61e-9 Cognitive performance; TGCT cis rs7091068 0.536 rs6583901 chr10:95409998 C/T cg20715218 chr10:95462985 C10orf4 -0.51 -5.52 -0.44 1.9e-7 Urinary tract infection frequency; TGCT cis rs950027 0.620 rs1426932 chr15:45687256 T/C cg14582100 chr15:45693742 SPATA5L1 0.43 5.38 0.44 3.52e-7 Response to fenofibrate (adiponectin levels); TGCT cis rs11098499 0.863 rs11098531 chr4:120465001 G/A cg09307838 chr4:120376055 NA 0.72 6.87 0.52 2.81e-10 Corneal astigmatism; TGCT cis rs12519773 0.597 rs4308464 chr5:92468867 G/C cg18783429 chr5:92414398 NA 0.31 4.65 0.39 8.41e-6 Migraine; TGCT cis rs4654899 0.812 rs7539512 chr1:21410791 A/G cg01072550 chr1:21505969 NA -0.56 -9.08 -0.63 2.14e-15 Superior frontal gyrus grey matter volume; TGCT cis rs7829975 0.846 rs11779061 chr8:8549432 G/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.1 -0.42 1.22e-6 Mood instability; TGCT cis rs986417 0.818 rs2057135 chr14:61077022 G/A cg27398547 chr14:60952738 C14orf39 1.33 9.79 0.66 4e-17 Gut microbiota (bacterial taxa); TGCT cis rs3087591 0.708 rs2854307 chr17:29652147 G/A cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT cis rs72615157 0.595 rs112241539 chr7:99847237 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.82 0.4 4.1e-6 Lung function (FEV1/FVC); TGCT cis rs4148883 0.629 rs2602899 chr4:100010128 C/T cg12011299 chr4:100065546 ADH4 0.38 5.72 0.46 7.41e-8 Alcohol dependence; TGCT cis rs9457247 1.000 rs2769354 chr6:167379771 G/T cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.08e-6 Crohn's disease; TGCT cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.7 0.39 6.81e-6 Prudent dietary pattern; TGCT cis rs9467773 1.000 rs9295695 chr6:26528250 C/T cg05738196 chr6:26577821 NA -0.89 -12.7 -0.75 3.46e-24 Intelligence (multi-trait analysis); TGCT cis rs17539620 0.624 rs871069 chr6:154837578 A/C cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs748404 0.631 rs1133395 chr15:43650384 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs28595532 0.841 rs10019311 chr4:119785458 G/A cg21605333 chr4:119757512 SEC24D 1.44 8.24 0.6 2.03e-13 Cannabis dependence symptom count; TGCT cis rs992157 0.764 rs10193189 chr2:219187603 C/A cg00012203 chr2:219082015 ARPC2 0.71 6.44 0.5 2.41e-9 Colorectal cancer; TGCT cis rs739496 0.579 rs7959619 chr12:112376597 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs694739 0.654 rs10897488 chr11:64140806 T/C cg23796481 chr11:64053134 BAD;GPR137 0.63 6.54 0.51 1.44e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9942416 0.601 rs114547168 chr5:74991903 A/G cg19683494 chr5:74908142 NA 0.57 5.96 0.47 2.39e-8 Age-related disease endophenotypes; TGCT cis rs7659604 0.517 rs56311153 chr4:122729685 T/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.31 -0.43 4.82e-7 Type 2 diabetes; TGCT cis rs7552404 1.000 rs7552404 chr1:76135946 A/G cg10523679 chr1:76189770 ACADM 0.92 10.14 0.67 5.73e-18 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs9951602 0.512 rs8089108 chr18:76651361 C/T cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs3733585 0.806 rs11723382 chr4:9954660 T/C cg11266682 chr4:10021025 SLC2A9 -0.61 -8.42 -0.6 7.65e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6964587 1.000 rs2188155 chr7:91599825 A/C cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs11098499 0.863 rs2291185 chr4:120434833 C/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs12681287 0.547 rs35871312 chr8:87543219 T/C cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT cis rs4478037 0.558 rs59482503 chr3:33077163 G/A cg19404215 chr3:33155277 CRTAP 1.04 4.99 0.41 2e-6 Major depressive disorder; TGCT cis rs6674176 0.696 rs4448553 chr1:44411589 A/G cg13606994 chr1:44402422 ARTN -0.49 -5.38 -0.44 3.51e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg09359103 chr1:154839909 KCNN3 -0.67 -12.42 -0.74 1.61e-23 Prostate cancer; TGCT cis rs4713118 0.527 rs35949862 chr6:28115367 A/T cg06395469 chr6:27635558 NA 0.37 4.62 0.38 9.33e-6 Parkinson's disease; TGCT cis rs4906332 1.000 rs35344594 chr14:103955792 A/G cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg01802117 chr1:53393560 SCP2 -0.41 -4.87 -0.4 3.32e-6 Monocyte count; TGCT cis rs7213347 0.780 rs9892016 chr17:2146422 A/G cg22033759 chr17:1182267 TUSC5 -0.22 -4.62 -0.38 9.53e-6 Total body bone mineral density; TGCT cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs5769765 0.819 rs9616377 chr22:50310880 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs28595532 0.764 rs56071514 chr4:119761833 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs72781680 0.898 rs7589440 chr2:24038595 G/A cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs9486719 1.000 rs12214469 chr6:97019471 G/T cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs9486715 0.867 rs211159 chr6:97023026 G/A cg18709589 chr6:96969512 KIAA0776 -0.85 -8.16 -0.59 3.2e-13 Headache; TGCT cis rs7095607 0.538 rs2673796 chr10:69917242 A/G cg18986048 chr10:69913749 MYPN 0.53 5.12 0.42 1.12e-6 Lung function (FVC); TGCT cis rs11792861 0.816 rs28361111 chr9:111761012 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.69 0.39 6.99e-6 Menarche (age at onset); TGCT cis rs769267 0.965 rs4808938 chr19:19401218 G/A cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT trans rs1814175 0.702 rs4881644 chr11:49786367 C/T cg15704280 chr7:45808275 SEPT13 -0.69 -8.05 -0.59 5.61e-13 Height; TGCT cis rs7312933 0.670 rs2406568 chr12:42552297 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7819412 0.511 rs2409799 chr8:11435927 G/C cg21775007 chr8:11205619 TDH -0.53 -5.01 -0.41 1.8e-6 Triglycerides; TGCT cis rs17767294 0.708 rs72849204 chr6:28170943 G/A cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs587847 0.558 rs614443 chr15:37683804 G/A cg16890051 chr15:37175029 LOC145845 -0.38 -4.52 -0.38 1.43e-5 Intraocular pressure; TGCT cis rs7568458 0.837 rs6547624 chr2:85802134 A/T cg17127132 chr2:85788382 GGCX 0.72 6.68 0.51 7.16e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6964587 1.000 rs2299232 chr7:91626699 A/C cg17063962 chr7:91808500 NA 0.88 9.54 0.65 1.69e-16 Breast cancer; TGCT cis rs10493773 0.928 rs12751296 chr1:86176968 G/A cg17807903 chr1:86174739 ZNHIT6 -0.38 -4.61 -0.38 9.67e-6 Urate levels in overweight individuals; TGCT cis rs10256972 0.616 rs6957733 chr7:1106327 T/G cg03188948 chr7:1209495 NA 0.47 5.81 0.46 4.9e-8 Longevity;Endometriosis; TGCT cis rs10927875 0.864 rs12744578 chr1:16173110 A/T cg14742211 chr1:16348397 CLCNKA -0.2 -4.46 -0.37 1.82e-5 Dilated cardiomyopathy; TGCT cis rs12134133 1.000 rs2802235 chr1:207471799 G/A cg02152968 chr1:207494213 CD55 0.57 4.51 0.38 1.48e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs2456568 0.564 rs4608039 chr11:93624799 C/G cg26875233 chr11:93583750 C11orf90 0.44 5.83 0.46 4.55e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9467711 0.606 rs9348726 chr6:26605206 G/A cg16898833 chr6:26189333 HIST1H4D 1.02 5.25 0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.830 rs28594127 chr4:99001121 T/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs1005277 0.579 rs2474588 chr10:38420870 A/G cg17830980 chr10:43048298 ZNF37B -0.85 -11.06 -0.7 3.31e-20 Extrinsic epigenetic age acceleration; TGCT cis rs13064411 0.735 rs6778800 chr3:113149236 A/G cg18753928 chr3:113234510 CCDC52 -0.67 -5.12 -0.42 1.14e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7666738 0.648 rs33988750 chr4:98985386 T/C cg17366294 chr4:99064904 C4orf37 0.65 4.68 0.39 7.36e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs72945132 0.882 rs67093918 chr11:70198999 C/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs8030485 0.728 rs13379886 chr15:79394894 A/G cg17916960 chr15:79447300 NA -0.32 -4.52 -0.38 1.41e-5 Left ventricle wall thickness; TGCT cis rs595982 0.527 rs35023389 chr19:49377873 G/A cg21252483 chr19:49399788 TULP2 -0.48 -7.32 -0.55 2.8e-11 Red cell distribution width; TGCT cis rs8017423 0.967 rs11159958 chr14:90716051 T/C cg04374321 chr14:90722782 PSMC1 0.72 7.54 0.56 8.86e-12 Mortality in heart failure; TGCT cis rs2836974 0.897 rs2776308 chr21:40715175 A/G cg17971929 chr21:40555470 PSMG1 0.91 7.93 0.58 1.07e-12 Cognitive function; TGCT cis rs1008375 0.618 rs13129002 chr4:17567513 A/G cg18681998 chr4:17616180 MED28 0.73 6.58 0.51 1.16e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17741873 0.779 rs3812635 chr10:75594302 T/G cg07699608 chr10:75541558 CHCHD1 0.72 5.15 0.42 1.02e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs2996428 0.601 rs59414187 chr1:3762815 T/C cg17848003 chr1:3704513 LRRC47 0.19 5.21 0.42 7.56e-7 Red cell distribution width; TGCT cis rs7666738 0.791 rs10005118 chr4:99038196 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs950776 0.612 rs8038920 chr15:78974545 A/G cg21242079 chr15:79101063 ADAMTS7 0.3 5.04 0.41 1.64e-6 Sudden cardiac arrest; TGCT cis rs1541995 0.931 rs12437634 chr15:96322790 T/A cg00882281 chr15:96346592 NA 0.28 4.56 0.38 1.2e-5 Photic sneeze reflex; TGCT trans rs561341 1.000 rs72821952 chr17:30248133 T/A cg20587970 chr11:113659929 NA -0.9 -8.59 -0.61 3.08e-14 Hip circumference adjusted for BMI; TGCT cis rs2346177 0.638 rs34186951 chr2:46657659 A/G cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.62 -0.38 9.52e-6 HDL cholesterol; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg24846343 chr22:24311635 DDTL 0.23 5.86 0.47 3.94e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg18252515 chr7:66147081 NA -1.2 -7.16 -0.54 6.16e-11 Diabetic kidney disease; TGCT cis rs116095464 0.558 rs7356696 chr5:284251 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs6582630 0.519 rs1607868 chr12:38385512 G/T cg26384229 chr12:38710491 ALG10B 0.85 7.58 0.56 7.17e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs909674 0.818 rs8137426 chr22:39844350 T/G cg01416388 chr22:39784598 NA -0.69 -6.32 -0.49 4.37e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs17601876 0.814 rs28674681 chr15:51559917 A/C cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2479724 0.935 rs7753507 chr6:41784094 C/T cg08135965 chr6:41755394 TOMM6 -0.48 -4.74 -0.39 5.77e-6 Menarche (age at onset); TGCT cis rs2455799 0.634 rs13085226 chr3:15923750 C/T cg16303742 chr3:15540471 COLQ -0.23 -4.52 -0.38 1.42e-5 Mean platelet volume; TGCT cis rs9814567 1.000 rs62271513 chr3:134298412 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.92 8.42 0.6 7.71e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg22166914 chr1:53195759 ZYG11B 0.35 5.78 0.46 5.7e-8 Monocyte count; TGCT trans rs1005277 0.522 rs7072977 chr10:37940440 C/A cg17830980 chr10:43048298 ZNF37B -0.67 -7.46 -0.56 1.32e-11 Extrinsic epigenetic age acceleration; TGCT cis rs6976053 0.875 rs7783543 chr7:100468398 T/C cg05669210 chr7:100450634 SLC12A9 0.51 4.5 0.37 1.56e-5 Plasminogen activator inhibitor type 1 levels (PAI-1); TGCT cis rs7542091 0.704 rs1883331 chr1:210043483 A/G cg21951975 chr1:209979733 IRF6 0.6 6.1 0.48 1.24e-8 Monobrow; TGCT cis rs11191270 0.554 rs77616533 chr10:104055983 A/G cg15320455 chr10:103880129 LDB1 0.85 5.35 0.43 4.09e-7 Intelligence (multi-trait analysis); TGCT cis rs394563 0.591 rs237018 chr6:149743930 A/G cg03678062 chr6:149772716 ZC3H12D -0.37 -4.79 -0.39 4.75e-6 Dupuytren's disease; TGCT cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg07507251 chr3:52567010 NT5DC2 0.48 6.67 0.51 7.55e-10 Bipolar disorder; TGCT cis rs36051895 0.659 rs10815150 chr9:5067301 C/A cg02405213 chr9:5042618 JAK2 -0.82 -12.07 -0.74 1.15e-22 Pediatric autoimmune diseases; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg10819733 chr22:24237672 NA 0.32 5.55 0.45 1.62e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg18252515 chr7:66147081 NA -1.3 -7.93 -0.58 1.1e-12 Diabetic kidney disease; TGCT cis rs2887571 0.821 rs11613567 chr12:1637740 G/C cg01940102 chr12:1095972 NA 0.25 4.67 0.39 7.69e-6 Bone mineral density; TGCT cis rs1401999 0.668 rs6806313 chr3:183642152 G/C cg01324343 chr3:183735012 ABCC5 0.73 8.92 0.63 5.17e-15 Anterior chamber depth; TGCT cis rs4730250 0.707 rs257387 chr7:106808480 G/A cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.6e-8 Osteoarthritis; TGCT cis rs6448317 0.954 rs11946846 chr4:24922703 G/A cg21108841 chr4:24914750 CCDC149 -0.63 -4.81 -0.4 4.29e-6 Heschl's gyrus morphology; TGCT cis rs858239 0.539 rs6975852 chr7:23186654 T/C cg05602783 chr7:23145260 KLHL7 -0.69 -5.71 -0.46 7.93e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs2836974 0.563 rs997147 chr21:40695325 A/G cg11644478 chr21:40555479 PSMG1 -0.54 -4.7 -0.39 6.69e-6 Cognitive function; TGCT cis rs7666738 0.830 rs17550610 chr4:99008273 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.647 rs4365346 chr17:17989373 G/T cg04398451 chr17:18023971 MYO15A -0.37 -6.51 -0.5 1.71e-9 Total body bone mineral density; TGCT cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.9 10.42 0.68 1.23e-18 Colorectal cancer; TGCT cis rs7666738 0.830 rs13144564 chr4:98939276 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs921968 0.643 rs559722 chr2:219398159 A/G cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs9914544 1.000 rs1037036 chr17:18764077 C/T cg26306683 chr17:18585705 ZNF286B 0.56 5.03 0.41 1.67e-6 Educational attainment (years of education); TGCT cis rs17125944 0.686 rs6572868 chr14:53325090 C/T cg00686598 chr14:53173677 PSMC6 -0.89 -4.62 -0.38 9.56e-6 Alzheimer's disease (late onset); TGCT cis rs514406 0.505 rs436363 chr1:53172163 T/C cg16325326 chr1:53192061 ZYG11B 0.86 12.09 0.74 1.05e-22 Monocyte count; TGCT cis rs11098499 0.818 rs7688802 chr4:120451668 G/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs11671005 0.735 rs45617039 chr19:58951096 G/A cg13877915 chr19:58951672 ZNF132 0.63 5.0 0.41 1.95e-6 Mean platelet volume; TGCT cis rs6088590 0.965 rs6120730 chr20:33385102 G/C cg06115741 chr20:33292138 TP53INP2 0.65 5.45 0.44 2.66e-7 Coronary artery disease; TGCT cis rs17473412 0.926 rs114335122 chr5:122652820 A/G cg15125798 chr5:122621645 NA -0.66 -5.93 -0.47 2.84e-8 Total body bone mineral density; TGCT cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg12751644 chr20:60527061 NA -0.49 -6.43 -0.5 2.5e-9 Obesity-related traits; TGCT cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4713118 0.513 rs149955 chr6:28036225 G/C cg10876282 chr6:28092338 ZSCAN16 0.49 4.54 0.38 1.33e-5 Parkinson's disease; TGCT cis rs9393777 0.513 rs7740197 chr6:26663478 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 0.58 4.63 0.38 9.02e-6 Intelligence (multi-trait analysis); TGCT cis rs4595586 0.545 rs2388175 chr12:39389217 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs6089584 0.526 rs6089619 chr20:60610916 C/T cg13770153 chr20:60521292 NA -0.41 -5.09 -0.42 1.28e-6 Body mass index; TGCT cis rs11118844 0.739 rs12070192 chr1:221945870 A/T cg04222084 chr1:221915650 DUSP10 -0.71 -5.03 -0.41 1.67e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs7772486 0.875 rs1960885 chr6:146325930 G/T cg05347473 chr6:146136440 FBXO30 0.52 4.9 0.4 2.93e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4654899 0.758 rs6693055 chr1:21421813 C/T cg01072550 chr1:21505969 NA -0.56 -9.08 -0.63 2.14e-15 Superior frontal gyrus grey matter volume; TGCT cis rs68170813 0.559 rs79978998 chr7:106845482 C/T cg02696742 chr7:106810147 HBP1 -0.67 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs7017914 0.905 rs1353058 chr8:71922018 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.06e-6 Bone mineral density; TGCT cis rs2742417 0.967 rs6800556 chr3:45752229 G/T cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs317689 0.819 rs317667 chr12:69703754 G/T cg14784868 chr12:69753453 YEATS4 0.57 4.9 0.4 2.96e-6 Response to diuretic therapy; TGCT cis rs12893668 0.572 rs4900591 chr14:104154878 G/A cg26031613 chr14:104095156 KLC1 -0.59 -5.05 -0.41 1.53e-6 Reticulocyte count; TGCT cis rs7773004 0.601 rs13210340 chr6:26326314 G/C cg16898833 chr6:26189333 HIST1H4D 1.34 5.61 0.45 1.23e-7 Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour); TGCT cis rs7589728 0.563 rs78685993 chr2:88447026 T/C cg04511125 chr2:88470314 THNSL2 0.79 6.55 0.51 1.37e-9 Plasma clusterin levels; TGCT cis rs17001868 0.568 rs9611311 chr22:40733951 T/C cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs2120019 0.938 rs13056 chr15:75312187 A/G cg11632617 chr15:75315747 PPCDC -0.3 -4.44 -0.37 1.95e-5 Blood trace element (Zn levels); TGCT cis rs7914558 0.752 rs7896519 chr10:104866863 C/T cg04362960 chr10:104952993 NT5C2 0.64 5.54 0.45 1.71e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7267979 0.966 rs416745 chr20:25438868 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6121246 0.697 rs6060446 chr20:30231637 T/C cg18721089 chr20:30220636 NA -0.53 -5.43 -0.44 2.86e-7 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg21724239 chr8:58056113 NA 0.39 4.59 0.38 1.07e-5 Developmental language disorder (linguistic errors); TGCT cis rs295137 0.798 rs1900706 chr2:201214071 A/C cg23649088 chr2:200775458 C2orf69 0.28 4.73 0.39 6.03e-6 Asthma (bronchodilator response); TGCT cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs4820539 1.000 rs3788347 chr22:23467804 G/A cg21100191 chr22:23484243 RTDR1 0.88 9.99 0.67 1.36e-17 Bone mineral density; TGCT cis rs7267979 0.549 rs11698185 chr20:25181998 T/C cg03522245 chr20:25566470 NINL 0.52 5.46 0.44 2.52e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1729951 0.546 rs12054219 chr3:136677472 G/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs4689388 0.926 rs4688987 chr4:6287329 C/T cg25554036 chr4:6271136 WFS1 0.57 8.21 0.59 2.47e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10791097 1.000 rs10791097 chr11:130718630 G/T cg12179176 chr11:130786555 SNX19 -0.6 -5.63 -0.45 1.15e-7 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11931598 0.511 rs4689576 chr4:7025523 T/C cg02503808 chr4:7069936 GRPEL1 0.54 5.13 0.42 1.07e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs1670533 1.000 rs6850784 chr4:1059809 G/A cg20887711 chr4:1340912 KIAA1530 0.65 5.14 0.42 1.05e-6 Recombination rate (females); TGCT cis rs10949834 0.730 rs2237503 chr7:73509326 G/C cg07137043 chr7:73588983 EIF4H -0.63 -4.64 -0.38 8.73e-6 Verbal memory performance (residualized delayed recall change); TGCT cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg18876405 chr7:65276391 NA 0.35 5.66 0.45 1.01e-7 Aortic root size; TGCT trans rs561341 0.941 rs72825746 chr17:30364610 G/A cg20587970 chr11:113659929 NA -1.09 -13.5 -0.77 4.23e-26 Hip circumference adjusted for BMI; TGCT cis rs523522 0.962 rs4766966 chr12:120942911 G/C cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs11098499 0.863 rs7664986 chr4:120429952 A/C cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.28e-9 Corneal astigmatism; TGCT cis rs4555082 0.794 rs2735827 chr14:105710600 T/A cg01266790 chr14:105781312 PACS2 0.54 4.44 0.37 1.95e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs854765 0.547 rs2955377 chr17:17932818 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.1 0.59 4.3e-13 Total body bone mineral density; TGCT cis rs2652822 0.550 rs72747098 chr15:63525249 G/A cg12855773 chr15:63363890 TPM1 -0.17 -5.09 -0.42 1.29e-6 Metabolic traits; TGCT cis rs68170813 0.617 rs2283041 chr7:107190415 A/G cg02696742 chr7:106810147 HBP1 -0.6 -4.66 -0.39 8.15e-6 Coronary artery disease; TGCT cis rs72949976 1.000 rs72949976 chr2:214034104 C/T cg08319019 chr2:214017104 IKZF2 -0.79 -7.3 -0.55 2.97e-11 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs7647973 1.000 rs56127630 chr3:49438036 C/G cg05785598 chr3:49045655 WDR6 -0.4 -4.67 -0.39 7.57e-6 Menarche (age at onset); TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs12200560 0.505 rs211162 chr6:97067344 G/A cg06623918 chr6:96969491 KIAA0776 0.61 5.19 0.42 8.52e-7 Coronary heart disease; TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg06873352 chr17:61820015 STRADA -0.5 -5.61 -0.45 1.23e-7 Prudent dietary pattern; TGCT trans rs4332037 0.539 rs11764780 chr7:2020904 G/C cg10840412 chr1:235813424 GNG4 0.93 6.69 0.51 6.97e-10 Bipolar disorder; TGCT cis rs36093844 0.898 rs11512932 chr11:85591130 T/G cg25872744 chr11:85566296 CCDC83 -0.52 -4.73 -0.39 6.09e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs4704846 1.000 rs4704846 chr5:156513344 G/A cg12943317 chr5:156479607 HAVCR1 -0.29 -4.44 -0.37 1.96e-5 Blood protein levels; TGCT cis rs7312933 0.607 rs7965392 chr12:42540280 G/A cg19980929 chr12:42632907 YAF2 0.47 6.43 0.5 2.47e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs3733585 0.566 rs35955619 chr4:9918986 T/A cg11266682 chr4:10021025 SLC2A9 -0.49 -5.86 -0.47 3.86e-8 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs617219 0.591 rs1840805 chr5:78565563 T/A cg23514016 chr5:78407564 BHMT -0.32 -4.88 -0.4 3.26e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs11031096 0.782 rs4910889 chr11:4153231 T/C cg18678763 chr11:4115507 RRM1 -0.46 -5.79 -0.46 5.36e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2204008 0.640 rs2320744 chr12:38162389 A/G cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs4819052 0.851 rs28616694 chr21:46674786 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.83 7.45 0.56 1.41e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs933688 1.000 rs12655973 chr5:90736537 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 8.92 0.63 4.99e-15 Smoking behavior; TGCT cis rs35146811 0.700 rs4729579 chr7:99780282 C/G cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs9677476 0.516 rs2175147 chr2:232008473 A/G cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs10114408 0.918 rs10992954 chr9:96647025 T/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs2956278 0.747 rs2929751 chr12:84677765 T/C cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2230307 0.536 rs684519 chr1:100604715 T/G cg24955406 chr1:100503596 HIAT1 -0.73 -4.96 -0.41 2.27e-6 Carotid intima media thickness; TGCT cis rs849210 0.517 rs3845806 chr2:206198319 A/G cg11793701 chr2:206547163 NRP2 -0.56 -4.51 -0.38 1.47e-5 Tonsillectomy; TGCT cis rs2153535 0.580 rs1577470 chr6:8462426 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs10892173 0.935 rs7108548 chr11:117674072 A/T cg21640587 chr11:117668038 DSCAML1 0.43 4.56 0.38 1.21e-5 Myopia; TGCT cis rs9811920 0.809 rs793475 chr3:99543764 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.03 0.41 1.7e-6 Axial length; TGCT cis rs7772486 0.875 rs2814863 chr6:146347299 C/T cg05347473 chr6:146136440 FBXO30 -0.56 -5.42 -0.44 2.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs991169 chr4:98928567 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11958404 0.789 rs72800604 chr5:157502940 C/T cg05962755 chr5:157440814 NA 0.36 4.66 0.39 7.94e-6 IgG glycosylation; TGCT cis rs2188554 0.740 rs213948 chr7:117194470 G/A cg08576598 chr7:116962626 WNT2 -0.35 -4.48 -0.37 1.68e-5 Esophageal adenocarcinoma; TGCT cis rs875971 1.000 rs1968225 chr7:65874773 T/C cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs2067615 0.507 rs10746063 chr12:107086240 G/T cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs2204008 0.775 rs8186812 chr12:38305055 C/T cg26384229 chr12:38710491 ALG10B 0.78 6.9 0.53 2.33e-10 Bladder cancer; TGCT cis rs9435341 0.860 rs12406721 chr1:107563243 G/T cg09367891 chr1:107599246 PRMT6 0.66 5.79 0.46 5.32e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs4820539 0.966 rs2283803 chr22:23454881 G/A cg21100191 chr22:23484243 RTDR1 0.9 10.8 0.7 1.43e-19 Bone mineral density; TGCT cis rs797680 0.822 rs2297707 chr1:93646207 T/C cg17826107 chr1:92977322 EVI5 -0.24 -5.24 -0.43 6.59e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2115630 1.000 rs4633690 chr15:85361960 C/T cg12501888 chr15:85177176 SCAND2 -0.53 -4.92 -0.4 2.69e-6 P wave terminal force; TGCT cis rs7681440 0.904 rs7680761 chr4:90763510 A/T cg20003494 chr4:90757398 SNCA -0.63 -6.09 -0.48 1.3e-8 Dementia with Lewy bodies; TGCT cis rs6121246 0.909 rs6060979 chr20:30417522 C/T cg13852791 chr20:30311386 BCL2L1 0.77 5.69 0.46 8.57e-8 Mean corpuscular hemoglobin; TGCT cis rs28735056 1.000 rs4798922 chr18:77628953 G/C cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs797680 0.856 rs1535701 chr1:93805201 T/G cg17826107 chr1:92977322 EVI5 -0.23 -5.16 -0.42 9.63e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7208859 0.673 rs9915963 chr17:29019643 C/T cg04154034 chr17:28927549 LRRC37B2 0.75 4.47 0.37 1.73e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12477438 0.520 rs11883676 chr2:99800814 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs3027234 0.727 rs79107119 chr17:8208481 G/C cg08322244 chr17:8066669 VAMP2 -0.57 -5.33 -0.43 4.55e-7 Telomere length; TGCT cis rs1982963 1.000 rs3818187 chr14:52509788 A/G cg10843707 chr14:52510701 NID2 0.43 6.57 0.51 1.22e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg12310025 chr6:25882481 NA 0.52 5.34 0.43 4.19e-7 Blood metabolite levels; TGCT cis rs9902453 0.933 rs7221154 chr17:28505024 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.62 -5.47 -0.44 2.42e-7 Coffee consumption (cups per day); TGCT cis rs6121246 0.697 rs6088856 chr20:30226543 C/G cg18721089 chr20:30220636 NA -0.55 -5.72 -0.46 7.56e-8 Mean corpuscular hemoglobin; TGCT cis rs11098499 0.909 rs1809406 chr4:120377122 G/A cg09307838 chr4:120376055 NA 0.71 6.98 0.53 1.57e-10 Corneal astigmatism; TGCT trans rs916888 0.773 rs199447 chr17:44812188 C/T cg22433210 chr17:43662623 NA 1.04 7.37 0.55 2.07e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs909674 0.731 rs6001594 chr22:39837472 C/T cg01416388 chr22:39784598 NA -0.74 -6.73 -0.52 5.61e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg08439880 chr3:133502540 NA -0.37 -7.01 -0.53 1.39e-10 Iron status biomarkers; TGCT cis rs7216064 1.000 rs59950564 chr17:65860859 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2730260 0.537 rs73169239 chr7:158884305 C/A cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs6933660 0.800 rs13201167 chr6:151773504 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.96 -11.08 -0.71 3.04e-20 Menarche (age at onset); TGCT cis rs11864453 0.749 rs7192730 chr16:72124219 T/C cg14768367 chr16:72042858 DHODH 0.5 4.8 0.4 4.5e-6 Fibrinogen levels; TGCT cis rs12478296 1.000 rs73007140 chr2:243010756 T/C cg06360820 chr2:242988706 NA -0.6 -4.96 -0.41 2.23e-6 Obesity-related traits; TGCT cis rs9467773 1.000 rs9467778 chr6:26534743 T/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs611744 0.967 rs645070 chr8:109216345 A/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs4699052 0.963 rs6533066 chr4:104163607 C/G cg16532752 chr4:104119610 CENPE -0.62 -5.78 -0.46 5.79e-8 Testicular germ cell tumor; TGCT cis rs9796 0.621 rs690733 chr15:41476465 G/A cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.17 -0.54 5.94e-11 Menopause (age at onset); TGCT cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg06481639 chr22:41940642 POLR3H 0.68 6.01 0.48 1.9e-8 Vitiligo; TGCT cis rs916888 0.773 rs538628 chr17:44787313 G/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.76 5.05 0.41 1.51e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1124769 0.525 rs11070812 chr15:51062492 G/T cg23028286 chr15:51614521 CYP19A1 0.19 4.47 0.37 1.75e-5 Cognitive performance; TGCT cis rs6088580 0.634 rs6087579 chr20:32985155 A/G cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs586688 1.000 rs647130 chr1:201637982 A/G cg07139329 chr1:201708558 NAV1 -0.41 -4.52 -0.38 1.41e-5 Obesity-related traits; TGCT cis rs6977955 1.000 rs67250450 chr7:28174986 T/C cg23620719 chr7:28220237 JAZF1 0.65 4.9 0.4 2.94e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs16958440 0.867 rs78854354 chr18:44666924 C/G cg17192377 chr18:44677553 HDHD2 0.65 4.67 0.39 7.78e-6 Sitting height ratio; TGCT cis rs2404602 0.716 rs12594577 chr15:76828793 A/C cg22467129 chr15:76604101 ETFA -0.56 -6.65 -0.51 8.35e-10 Blood metabolite levels; TGCT cis rs910316 1.000 rs4903279 chr14:75546583 C/T cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs9467711 1.000 rs6939978 chr6:26328462 G/C cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs644799 0.965 rs3789960 chr11:95509037 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.82 0.7 1.31e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12210905 1.000 rs12198077 chr6:27169307 A/C cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs11718455 0.653 rs28533958 chr3:43974179 C/A cg08738300 chr3:44038990 NA 0.75 5.71 0.46 7.9e-8 Coronary artery disease; TGCT cis rs6840360 0.615 rs4696267 chr4:152464500 A/G cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg09222892 chr1:25734099 RHCE -0.44 -7.17 -0.54 5.87e-11 Erythrocyte sedimentation rate; TGCT cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4555082 1.000 rs7146012 chr14:105757566 G/A cg10792982 chr14:105748885 BRF1 0.22 4.48 0.37 1.7e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs10465746 0.780 rs2147392 chr1:84404154 C/A cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT cis rs7429990 0.813 rs7627568 chr3:48093052 A/T cg11946769 chr3:48343235 NME6 -0.52 -4.51 -0.38 1.48e-5 Educational attainment (years of education); TGCT cis rs12220238 0.915 rs7922519 chr10:75976573 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1865760 1.000 rs9358895 chr6:25924655 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.21 0.49 7.42e-9 Height; TGCT cis rs587847 0.737 rs28672197 chr15:37628310 G/C cg00216138 chr15:37171175 LOC145845 0.31 4.52 0.38 1.41e-5 Intraocular pressure; TGCT cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg23758822 chr17:41437982 NA 0.72 6.85 0.52 3.09e-10 Menopause (age at onset); TGCT cis rs1799949 0.628 rs4474733 chr17:41433660 G/T cg23758822 chr17:41437982 NA 0.54 4.45 0.37 1.92e-5 Menopause (age at onset); TGCT trans rs1814175 0.817 rs11040474 chr11:49708441 G/A cg03929089 chr4:120376271 NA -0.71 -8.36 -0.6 1.09e-13 Height; TGCT cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg17971929 chr21:40555470 PSMG1 0.96 9.05 0.63 2.44e-15 Cognitive function; TGCT cis rs4601821 0.858 rs2298489 chr11:113235419 C/T cg14159747 chr11:113255604 NA -0.43 -4.86 -0.4 3.53e-6 Alcoholic chronic pancreatitis; TGCT cis rs78456975 1.000 rs11883965 chr2:1560062 T/C cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2708977 1.000 rs2708977 chr2:97230074 G/A cg01950434 chr2:97203154 ARID5A -0.66 -6.09 -0.48 1.34e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs6835098 1.000 rs2332654 chr4:174088399 C/T cg08422745 chr4:174089978 GALNT7 -0.95 -11.46 -0.72 3.51e-21 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs2688608 0.620 rs7076525 chr10:75512797 C/T cg23231163 chr10:75533350 FUT11 -0.28 -4.86 -0.4 3.51e-6 Inflammatory bowel disease; TGCT cis rs7017914 0.967 rs7000647 chr8:71688408 C/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs7208859 0.623 rs216439 chr17:28927884 T/C cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7091068 0.616 rs7920366 chr10:95497178 A/T cg20715218 chr10:95462985 C10orf4 0.52 4.62 0.38 9.33e-6 Urinary tract infection frequency; TGCT cis rs10479542 0.766 rs7733389 chr5:178974997 C/T cg22764044 chr5:178986830 RUFY1 0.43 4.87 0.4 3.38e-6 Lung cancer; TGCT cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs12541335 0.639 rs7834182 chr8:22163112 G/A cg02463440 chr8:22132932 PIWIL2 0.26 5.14 0.42 1.05e-6 Hypertriglyceridemia; TGCT cis rs6952808 0.689 rs79950306 chr7:2022063 C/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.43 -0.5 2.5e-9 Bipolar disorder and schizophrenia; TGCT cis rs7100689 0.784 rs7895042 chr10:82095276 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.92 0.58 1.15e-12 Post bronchodilator FEV1; TGCT cis rs2797160 1.000 rs6569435 chr6:125998186 T/C cg05901451 chr6:126070800 HEY2 -0.74 -6.58 -0.51 1.18e-9 Endometrial cancer; TGCT cis rs7746199 0.736 rs6904596 chr6:27491299 G/A cg01031101 chr6:28227091 NKAPL -0.53 -4.53 -0.38 1.39e-5 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs7829975 0.577 rs7816329 chr8:8543843 G/A cg15556689 chr8:8085844 FLJ10661 -0.53 -4.5 -0.37 1.53e-5 Mood instability; TGCT cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg18252515 chr7:66147081 NA 1.13 6.81 0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg05665937 chr4:1216051 CTBP1 0.25 4.68 0.39 7.33e-6 Obesity-related traits; TGCT cis rs4689388 0.926 rs4689394 chr4:6291003 C/G cg00701064 chr4:6280414 WFS1 -0.38 -4.86 -0.4 3.47e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.62 -6.05 -0.48 1.62e-8 Intelligence (multi-trait analysis); TGCT cis rs9400467 0.537 rs55643604 chr6:111490648 T/G cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs4689388 0.824 rs6446482 chr4:6295693 C/G cg00701064 chr4:6280414 WFS1 0.4 5.09 0.42 1.28e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2070488 1.000 rs3792528 chr3:38493303 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 9.84 0.66 3.06e-17 Electrocardiographic conduction measures; TGCT cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg22442454 chr1:209979470 IRF6 0.63 4.65 0.39 8.22e-6 Cleft lip with or without cleft palate; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg01516881 chr6:292596 DUSP22 -0.81 -8.52 -0.61 4.63e-14 Menopause (age at onset); TGCT cis rs514406 0.547 rs377808 chr1:53190359 T/G cg08859206 chr1:53392774 SCP2 -0.34 -4.9 -0.4 2.93e-6 Monocyte count; TGCT cis rs11190604 1.000 rs2489040 chr10:102331298 G/A cg23241863 chr10:102295624 HIF1AN 0.67 5.1 0.42 1.23e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2692947 0.644 rs2969491 chr2:96794982 C/T cg22654517 chr2:96458247 NA 0.22 4.58 0.38 1.11e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2204008 0.560 rs4129033 chr12:38301897 A/T cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs6840360 0.539 rs1443087 chr4:152450095 C/A cg17479576 chr4:152424074 FAM160A1 -0.57 -6.02 -0.48 1.85e-8 Intelligence (multi-trait analysis); TGCT cis rs6964587 1.000 rs2282970 chr7:91584281 A/G cg17063962 chr7:91808500 NA 0.9 9.92 0.67 2e-17 Breast cancer; TGCT cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg10117171 chr1:25599238 RHD -0.35 -5.72 -0.46 7.6e-8 Erythrocyte sedimentation rate; TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs9807989 0.524 rs7591246 chr2:102999403 C/A cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs13242816 1.000 rs56275709 chr7:116108489 A/G cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs6912958 0.712 rs6454640 chr6:88370352 G/T cg08069147 chr6:88032118 GJB7;C6orf162 0.49 4.76 0.39 5.4e-6 Monocyte percentage of white cells; TGCT cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg27588902 chr6:42928151 GNMT -0.5 -5.96 -0.47 2.49e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12136530 0.577 rs4481878 chr1:19791086 C/A cg18923740 chr1:19971790 NBL1 -0.45 -4.9 -0.4 2.91e-6 Lead levels in blood; TGCT cis rs1971256 0.563 rs76363440 chr6:151767483 A/G cg03627880 chr6:151815985 C6orf97 0.47 4.76 0.39 5.36e-6 Endometriosis; TGCT cis rs28595532 0.920 rs56124677 chr4:119772213 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs72945132 0.882 rs72949076 chr11:70217695 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.21 0.54 4.95e-11 Coronary artery disease; TGCT cis rs13064411 0.735 rs13098166 chr3:113210038 A/G cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7829975 0.501 rs2980769 chr8:8320291 G/A cg08975724 chr8:8085496 FLJ10661 0.6 5.44 0.44 2.72e-7 Mood instability; TGCT cis rs1215050 0.791 rs968854 chr4:98837863 T/C cg17366294 chr4:99064904 C4orf37 0.57 6.13 0.48 1.08e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4805272 0.512 rs11879141 chr19:29320335 G/A cg14983838 chr19:29218262 NA 0.69 4.7 0.39 6.67e-6 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs11190604 1.000 rs2489040 chr10:102331298 G/A cg16342193 chr10:102329863 NA -0.42 -5.39 -0.44 3.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10782582 0.609 rs2029680 chr1:76363505 A/C cg03433033 chr1:76189801 ACADM -0.5 -4.92 -0.4 2.7e-6 Daytime sleep phenotypes; TGCT cis rs425277 0.606 rs12082939 chr1:2078922 C/T cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.54 -0.38 1.34e-5 Height; TGCT cis rs9329289 0.510 rs12356215 chr10:2545390 C/G cg07014206 chr10:2547000 NA -0.28 -4.53 -0.38 1.36e-5 Age-related hearing impairment; TGCT cis rs896854 0.573 rs11996455 chr8:95853708 G/A cg13393036 chr8:95962371 TP53INP1 -0.51 -6.26 -0.49 5.79e-9 Type 2 diabetes; TGCT cis rs35883536 0.588 rs955337 chr1:101108834 A/T cg06223162 chr1:101003688 GPR88 0.33 5.61 0.45 1.27e-7 Monocyte count; TGCT cis rs116095464 0.558 rs61689490 chr5:224904 T/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs7091068 0.536 rs7893369 chr10:95410147 A/G cg20715218 chr10:95462985 C10orf4 0.51 5.79 0.46 5.52e-8 Urinary tract infection frequency; TGCT cis rs1799949 0.965 rs4792989 chr17:41437552 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.17 0.42 9.27e-7 Menopause (age at onset); TGCT trans rs1974653 0.672 rs28610569 chr22:20071351 A/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs10504229 0.679 rs72649107 chr8:58030453 C/A cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.587 rs7036761 chr9:5198781 A/C cg02405213 chr9:5042618 JAK2 0.7 8.48 0.61 5.5e-14 Pediatric autoimmune diseases; TGCT cis rs969413 0.624 rs9914093 chr17:79260653 C/G cg27412613 chr17:79183705 AZI1 -0.23 -4.57 -0.38 1.16e-5 Frontotemporal dementia; TGCT cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs6450176 0.857 rs1541680 chr5:53304725 G/A ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs910316 1.000 rs10146482 chr14:75574087 C/T cg23033748 chr14:75592666 NEK9 0.27 4.66 0.39 8.07e-6 Height; TGCT cis rs875971 0.862 rs778705 chr7:65861115 G/A cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs6500602 0.819 rs3747580 chr16:4455675 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 5.65 0.45 1.05e-7 Schizophrenia; TGCT cis rs9916302 0.706 rs2302073 chr17:37457342 A/G cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT trans rs1415174 0.958 rs10873836 chr1:87844420 A/G cg23065576 chr20:25207247 ENTPD6 -0.27 -6.8 -0.52 3.88e-10 Breast cancer; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs62103177 0.733 rs62096747 chr18:77619568 A/G cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs7172809 0.573 rs1374201 chr15:77477873 G/A cg22256960 chr15:77711686 NA -0.49 -4.63 -0.38 9.01e-6 Glucose homeostasis traits; TGCT cis rs8180040 1.000 rs807936 chr3:47322496 C/T cg27129171 chr3:47204927 SETD2 0.7 8.89 0.62 5.88e-15 Colorectal cancer; TGCT cis rs9733 0.596 rs6587518 chr1:150661787 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.84 0.4 3.83e-6 Tonsillectomy; TGCT cis rs727563 0.593 rs5758461 chr22:42162189 G/C cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9913156 0.707 rs9902000 chr17:4582426 A/C cg00122941 chr17:4613640 ARRB2 -0.84 -7.41 -0.55 1.72e-11 Lymphocyte counts; TGCT cis rs6912958 0.781 rs3757368 chr6:88224495 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg24531977 chr5:56204891 C5orf35 -0.78 -7.67 -0.57 4.41e-12 Initial pursuit acceleration; TGCT cis rs67311347 1.000 rs6599102 chr3:40468406 G/A cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs360798 0.532 rs360797 chr2:62942840 C/T cg17519650 chr2:63277830 OTX1 -0.55 -4.73 -0.39 5.96e-6 Coronary artery disease; TGCT cis rs9494142 0.592 rs1547247 chr6:135390836 C/T cg22676075 chr6:135203613 NA 0.49 4.53 0.38 1.38e-5 Lymphocyte counts;Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9926296 0.605 rs8046243 chr16:89852133 A/G cg21285383 chr16:89894308 SPIRE2 0.46 7.16 0.54 6.15e-11 Vitiligo; TGCT cis rs7172809 0.897 rs16968895 chr15:77825121 A/G cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs1497406 0.744 rs7538216 chr1:16509671 T/C cg20430773 chr1:16534157 ARHGEF19 0.55 6.11 0.48 1.18e-8 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs35306767 0.623 rs34034003 chr10:1143435 G/A cg20503657 chr10:835505 NA 0.51 5.41 0.44 3.18e-7 Eosinophil percentage of granulocytes; TGCT cis rs41271951 0.512 rs12068365 chr1:151015868 G/A cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs7829975 0.560 rs6994131 chr8:8550958 G/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.31 -0.43 4.81e-7 Mood instability; TGCT cis rs2594989 0.943 rs2454502 chr3:11499331 T/C cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.58e-5 Circulating chemerin levels; TGCT cis rs7666738 0.830 rs7662596 chr4:99019962 G/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9811920 0.770 rs4928237 chr3:99731330 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.18 0.42 8.58e-7 Axial length; TGCT cis rs13191362 1.000 rs73035025 chr6:163000988 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4455778 0.600 rs4244233 chr7:49130572 T/A cg26309511 chr7:48887640 NA 0.51 6.59 0.51 1.12e-9 Lung cancer in never smokers; TGCT cis rs12477438 0.501 rs7349217 chr2:99815146 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.06 0.84 2.55e-34 Chronic sinus infection; TGCT cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg18252515 chr7:66147081 NA 1.17 7.17 0.54 5.94e-11 Diabetic kidney disease; TGCT cis rs1372520 0.935 rs2245801 chr4:90757840 T/C cg20003494 chr4:90757398 SNCA -0.65 -4.89 -0.4 3.12e-6 Neuroticism; TGCT cis rs2072499 0.966 rs2842869 chr1:156160696 A/G cg24450063 chr1:156163899 SLC25A44 1.19 17.21 0.84 1.15e-34 Testicular germ cell tumor; TGCT cis rs933688 1.000 rs6452951 chr5:90653868 T/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.03 9.42 0.65 3.21e-16 Smoking behavior; TGCT cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.88 9.32 0.64 5.46e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs2235642 0.717 rs2236269 chr16:1652614 T/A cg00463982 chr16:1583984 IFT140;TMEM204 -0.26 -4.46 -0.37 1.79e-5 Coronary artery disease; TGCT cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg10802521 chr3:52805072 NEK4 -0.7 -8.75 -0.62 1.28e-14 Bipolar disorder; TGCT cis rs7085104 0.700 rs3740397 chr10:104592675 G/C cg15744005 chr10:104629667 AS3MT -0.42 -5.22 -0.42 7.24e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7113874 0.524 rs9300090 chr11:8585384 G/A cg14521421 chr11:8862019 ST5 0.3 4.6 0.38 1.01e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg20007245 chr22:24372913 LOC391322 0.82 7.03 0.53 1.2e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs78487399 0.614 rs10166376 chr2:43622472 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.8 -0.4 4.39e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11098499 0.954 rs10006525 chr4:120408931 T/G cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs16854884 0.683 rs2053211 chr3:143774592 C/T cg06585982 chr3:143692056 C3orf58 -0.53 -4.47 -0.37 1.72e-5 Economic and political preferences (feminism/equality); TGCT cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg11062466 chr8:58055876 NA 0.43 4.52 0.38 1.45e-5 Developmental language disorder (linguistic errors); TGCT cis rs709400 0.663 rs7145113 chr14:103945414 A/G cg26031613 chr14:104095156 KLC1 0.84 9.64 0.65 9.34e-17 Body mass index; TGCT trans rs7726839 0.540 rs4957083 chr5:659343 T/C cg25482853 chr8:67687455 SGK3 1.2 10.13 0.67 6.02e-18 Obesity-related traits; TGCT cis rs7267979 1.000 rs2259956 chr20:25282433 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs9951602 0.512 rs8085719 chr18:76649111 A/G cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs17345786 0.798 rs4257518 chr3:101281709 C/T cg12386194 chr3:101231763 SENP7 -0.56 -5.39 -0.44 3.41e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg05665937 chr4:1216051 CTBP1 0.24 4.63 0.38 8.9e-6 Obesity-related traits; TGCT cis rs9296092 0.517 rs9461877 chr6:33516667 C/T cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.08e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs13315871 1.000 rs71311870 chr3:58399283 T/C cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs2777491 0.957 rs6493002 chr15:41709195 C/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.01 -0.7 4.47e-20 Ulcerative colitis; TGCT cis rs73001065 0.901 rs73004933 chr19:19675696 C/T cg03709012 chr19:19516395 GATAD2A 1.03 5.03 0.41 1.65e-6 LDL cholesterol; TGCT cis rs7772486 0.692 rs2265915 chr6:146194332 A/T cg23711669 chr6:146136114 FBXO30 0.97 11.36 0.71 6.35e-21 Lobe attachment (rater-scored or self-reported); TGCT cis rs9527 0.590 rs34104646 chr10:104896078 T/A cg04362960 chr10:104952993 NT5C2 0.69 5.82 0.46 4.78e-8 Arsenic metabolism; TGCT cis rs61990749 0.597 rs1048147 chr14:78139988 C/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.68 -4.76 -0.39 5.29e-6 Fibroblast growth factor basic levels; TGCT cis rs4648739 0.613 rs13303201 chr1:1903712 G/T cg14196676 chr1:1911069 KIAA1751 -0.48 -7.47 -0.56 1.26e-11 Severe influenza A (H1N1) infection; TGCT cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg11890956 chr21:40555474 PSMG1 1.12 12.45 0.75 1.39e-23 Cognitive function; TGCT cis rs4663866 0.908 rs35093813 chr2:239153765 T/A cg17283117 chr2:239148619 HES6 0.98 4.5 0.37 1.55e-5 Irritable bowel syndrome; TGCT cis rs11644362 1.000 rs12934970 chr16:12988077 G/C cg06890432 chr16:12997467 SHISA9 -0.59 -6.47 -0.5 2.04e-9 Positive affect;Subjective well-being; TGCT cis rs4886920 0.563 rs8037968 chr15:78077762 C/T cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs9534288 0.797 rs7998854 chr13:46592174 C/A cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs12479064 0.724 rs112900993 chr2:99948805 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -6.33 -0.49 4.06e-9 Chronic sinus infection; TGCT cis rs1552244 0.882 rs17050699 chr3:10037167 G/A cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs17376456 0.741 rs12374432 chr5:93481348 C/A cg21475434 chr5:93447410 FAM172A 0.64 4.76 0.39 5.35e-6 Diabetic retinopathy; TGCT trans rs2469997 1.000 rs2469999 chr8:120354695 G/A cg01792902 chr3:178864926 PIK3CA 0.78 6.66 0.51 7.93e-10 Hypertension (SNP x SNP interaction); TGCT cis rs78487399 0.908 rs80144434 chr2:43844640 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.58 0.38 1.12e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3733585 0.699 rs6856127 chr4:9965443 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2115630 1.000 rs4633690 chr15:85361960 C/T cg11189052 chr15:85197271 WDR73 -0.64 -5.97 -0.47 2.31e-8 P wave terminal force; TGCT cis rs2710642 0.888 rs2539985 chr2:63134507 T/A cg17519650 chr2:63277830 OTX1 0.58 5.07 0.41 1.4e-6 LDL cholesterol levels;LDL cholesterol; TGCT cis rs7809950 0.678 rs3801966 chr7:106824580 G/A cg23024343 chr7:107201750 COG5 -0.44 -5.82 -0.46 4.67e-8 Coronary artery disease; TGCT cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs13242816 1.000 rs4292624 chr7:116102724 A/C cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs7917772 0.582 rs10786680 chr10:104317192 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2153535 0.563 rs7739249 chr6:8534590 C/G cg23788917 chr6:8435910 SLC35B3 0.64 5.8 0.46 5.23e-8 Motion sickness; TGCT cis rs1552244 0.882 rs56224841 chr3:10044014 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2974760 0.606 rs6600143 chr16:201389 A/C cg08400316 chr16:204221 HBZ -0.71 -7.56 -0.56 7.85e-12 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9549367 0.789 rs9549695 chr13:113874814 A/G cg18105134 chr13:113819100 PROZ 0.29 5.09 0.42 1.31e-6 Platelet distribution width; TGCT cis rs9653442 0.593 rs7597861 chr2:100853187 G/A cg07810366 chr2:100720526 AFF3 -0.41 -6.21 -0.49 7.19e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2932538 0.922 rs12136781 chr1:113090655 C/T cg22162597 chr1:113214053 CAPZA1 0.27 5.89 0.47 3.46e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs3774830 0.714 rs12509727 chr4:5470800 T/G cg26943120 chr4:5472116 STK32B 0.29 7.0 0.53 1.39e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9902453 0.791 rs57719820 chr17:28335088 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs2688608 0.560 rs10128354 chr10:75470045 T/C cg23231163 chr10:75533350 FUT11 -0.27 -4.56 -0.38 1.19e-5 Inflammatory bowel disease; TGCT cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg17264618 chr3:40429014 ENTPD3 0.31 4.59 0.38 1.09e-5 Renal cell carcinoma; TGCT cis rs7552404 0.731 rs7523573 chr1:76372020 G/T cg10523679 chr1:76189770 ACADM 0.82 7.13 0.54 7.21e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2249625 0.545 rs2496495 chr6:72882414 G/A cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT trans rs7618501 0.602 rs7642934 chr3:50174848 G/A cg21659725 chr3:3221576 CRBN -0.76 -9.11 -0.63 1.8e-15 Intelligence (multi-trait analysis); TGCT cis rs587847 0.737 rs56383924 chr15:37604790 C/T cg00216138 chr15:37171175 LOC145845 0.3 4.52 0.38 1.43e-5 Intraocular pressure; TGCT cis rs1483890 0.723 rs6419767 chr3:69412505 G/A cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg02953382 chr22:24373134 LOC391322 0.82 7.01 0.53 1.37e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs854765 0.619 rs1101727 chr17:18016148 T/C cg04398451 chr17:18023971 MYO15A -0.38 -6.51 -0.5 1.65e-9 Total body bone mineral density; TGCT cis rs11098499 0.866 rs9991221 chr4:120292107 G/C cg09307838 chr4:120376055 NA 0.58 5.75 0.46 6.63e-8 Corneal astigmatism; TGCT cis rs228437 0.507 rs440170 chr6:134904442 C/T cg09872934 chr6:134495829 SGK1 0.51 4.63 0.38 9e-6 Melanoma; TGCT cis rs6831352 0.851 rs1230164 chr4:99986023 C/G cg12011299 chr4:100065546 ADH4 0.4 4.57 0.38 1.18e-5 Alcohol dependence; TGCT cis rs3858526 0.796 rs9645652 chr11:5944264 C/T cg05234568 chr11:5960015 NA -0.45 -4.46 -0.37 1.84e-5 DNA methylation (variation); TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg11141652 chr22:24348549 GSTTP1 0.33 4.53 0.38 1.39e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs986417 0.818 rs8005621 chr14:61106699 G/A cg18240143 chr14:60952599 C14orf39 0.88 4.57 0.38 1.15e-5 Gut microbiota (bacterial taxa); TGCT cis rs7666738 0.830 rs9998682 chr4:98939009 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2932538 0.961 rs12126494 chr1:113228623 G/A cg22162597 chr1:113214053 CAPZA1 0.24 4.97 0.41 2.21e-6 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT trans rs8073060 0.505 rs225276 chr17:33973034 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs11148252 0.774 rs7334583 chr13:52930352 G/T cg00495681 chr13:53174319 NA -0.57 -5.51 -0.44 1.96e-7 Lewy body disease; TGCT cis rs807669 0.505 rs8142503 chr22:19166717 G/T cg02655711 chr22:19163373 SLC25A1 0.25 4.67 0.39 7.78e-6 Metabolite levels; TGCT trans rs1814175 0.817 rs10839318 chr11:49657511 G/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.64 -0.61 2.33e-14 Height; TGCT cis rs2242116 0.932 rs4683301 chr3:46931478 A/T cg02527881 chr3:46936655 PTH1R 0.31 6.27 0.49 5.55e-9 Birth weight; TGCT cis rs2070433 0.948 rs2839304 chr21:47952650 C/G cg12379764 chr21:47803548 PCNT -0.51 -4.56 -0.38 1.22e-5 Lymphocyte counts; TGCT cis rs1371867 0.846 rs1660351 chr8:101275034 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.5 -0.37 1.53e-5 Atrioventricular conduction; TGCT cis rs240764 0.687 rs1336245 chr6:101197640 A/T cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs7043114 0.525 rs10283572 chr9:95133074 G/A cg14311495 chr9:95764742 FGD3 -0.22 -4.47 -0.37 1.75e-5 Height; TGCT cis rs9296092 0.538 rs7761464 chr6:33519417 C/A cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7943191 0.768 rs34065644 chr11:62371938 C/T cg13298116 chr11:62369859 EML3;MTA2 0.6 7.25 0.55 3.98e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs35146811 0.696 rs1727124 chr7:99804104 T/G cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.62 -0.38 9.32e-6 Coronary artery disease; TGCT cis rs796364 0.762 rs13030712 chr2:200973569 G/A cg23649088 chr2:200775458 C2orf69 0.43 6.93 0.53 1.98e-10 Schizophrenia; TGCT cis rs3020736 0.500 rs11090076 chr22:42514190 T/C cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12049351 0.774 rs6678721 chr1:229623131 G/C cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg03806693 chr22:41940476 POLR3H -1.03 -10.47 -0.68 9.18e-19 Vitiligo; TGCT cis rs79976124 0.876 rs17511913 chr6:66644361 C/T cg07460842 chr6:66804631 NA 0.57 5.22 0.42 7.44e-7 Type 2 diabetes; TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg05215272 chr17:6899095 ALOX12 0.57 6.79 0.52 4.04e-10 Tonsillectomy; TGCT cis rs9549367 0.826 rs35306827 chr13:113869045 G/A cg00898013 chr13:113819073 PROZ -0.42 -5.19 -0.42 8.26e-7 Platelet distribution width; TGCT cis rs950027 0.620 rs1145084 chr15:45675440 G/A cg26924012 chr15:45694286 SPATA5L1 0.8 8.85 0.62 7.53e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs910316 0.967 rs35446981 chr14:75637351 A/T cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.84e-6 Height; TGCT cis rs10464366 0.746 rs17171537 chr7:39145647 C/T cg18850127 chr7:39170497 POU6F2 0.3 6.61 0.51 1e-9 IgG glycosylation; TGCT cis rs208520 0.586 rs208442 chr6:66900618 T/A cg07460842 chr6:66804631 NA -0.67 -6.69 -0.52 6.82e-10 Exhaled nitric oxide output; TGCT cis rs56104184 0.723 rs73063522 chr19:49408358 C/G cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs1218582 0.772 rs4240874 chr1:154885779 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs7507204 0.680 rs12975645 chr19:3419132 A/G cg08380311 chr19:3435252 NFIC 0.96 8.22 0.59 2.32e-13 Height; TGCT cis rs73001065 0.591 rs56273306 chr19:19621004 T/C cg03709012 chr19:19516395 GATAD2A 0.93 4.98 0.41 2.1e-6 LDL cholesterol; TGCT cis rs11098499 0.863 rs3775854 chr4:120471971 C/T cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg13695892 chr22:41940480 POLR3H -0.89 -8.88 -0.62 6.27e-15 Vitiligo; TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg19318889 chr4:1322082 MAEA 0.27 6.66 0.51 8.13e-10 Longevity; TGCT cis rs4665809 0.938 rs4665822 chr2:26312555 C/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs17601876 0.843 rs28490942 chr15:51559845 G/C cg19946085 chr15:51559439 CYP19A1 -0.33 -4.98 -0.41 2.04e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs6671200 1.000 rs34037437 chr1:95660921 C/G cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs2832191 1.000 rs6516891 chr21:30483070 C/T cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs7617480 0.587 rs9311431 chr3:48848787 T/A cg07636037 chr3:49044803 WDR6 0.79 6.43 0.5 2.54e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7267979 0.873 rs6115093 chr20:25210730 C/T cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.52e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5769707 0.846 rs5770610 chr22:50036897 A/C cg05373962 chr22:49881684 NA -0.31 -6.42 -0.5 2.6e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs910316 0.874 rs61980828 chr14:75630378 G/A cg11812906 chr14:75593930 NEK9 -0.75 -7.44 -0.56 1.43e-11 Height; TGCT cis rs2439831 0.867 rs2242068 chr15:43699304 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.06 7.75 0.57 2.79e-12 Lung cancer in ever smokers; TGCT cis rs6964587 1.000 rs2282975 chr7:91761638 A/G cg22709100 chr7:91322751 NA 0.28 4.52 0.38 1.44e-5 Breast cancer; TGCT cis rs6589563 0.609 rs56224630 chr11:116627097 G/A cg20660624 chr11:117307972 DSCAML1 -0.38 -4.99 -0.41 2.02e-6 Eosinophil counts; TGCT cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg18230493 chr5:56204884 C5orf35 0.85 6.61 0.51 1.05e-9 Initial pursuit acceleration; TGCT cis rs4888262 0.508 rs7189123 chr16:74540097 C/A cg01733217 chr16:74700730 RFWD3 0.68 6.88 0.53 2.6200000000000003e-10 Testicular germ cell tumor; TGCT cis rs9467711 0.538 rs35942482 chr6:26444938 T/A cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs1891498 0.602 rs10793706 chr1:147243753 C/G cg17941330 chr1:147245494 GJA5 0.36 4.81 0.4 4.36e-6 Cognitive performance; TGCT cis rs2594989 0.836 rs1546231 chr3:11513678 T/G cg00170343 chr3:11313890 ATG7 0.7 5.22 0.42 7.17e-7 Circulating chemerin levels; TGCT cis rs7666738 0.830 rs10470894 chr4:99039107 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.568 rs2413656 chr22:42129357 G/T cg06481639 chr22:41940642 POLR3H 0.55 4.62 0.38 9.38e-6 Vitiligo; TGCT cis rs4689388 0.889 rs13128674 chr4:6294517 C/T cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1865760 0.865 rs9467641 chr6:25947236 T/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs9341808 0.718 rs9352806 chr6:80980057 G/T cg08355045 chr6:80787529 NA 0.28 4.75 0.39 5.41e-6 Sitting height ratio; TGCT cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg03517284 chr6:25882590 NA 0.53 5.48 0.44 2.3e-7 Blood metabolite levels; TGCT cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg17971929 chr21:40555470 PSMG1 -0.67 -6.27 -0.49 5.46e-9 Cognitive function; TGCT cis rs2075671 0.903 rs11983334 chr7:100302434 C/T cg20848291 chr7:100343083 ZAN -0.52 -4.56 -0.38 1.21e-5 Other erythrocyte phenotypes; TGCT cis rs11190604 1.000 rs2489037 chr10:102319918 A/G cg16342193 chr10:102329863 NA 0.43 5.39 0.44 3.43e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs59107033 0.563 rs6802207 chr3:123124811 A/C cg04890266 chr3:123102914 ADCY5 -0.37 -5.59 -0.45 1.39e-7 Lymphocyte counts; TGCT cis rs9549260 0.651 rs57735994 chr13:41226561 C/G cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs9911578 0.935 rs34523895 chr17:57034095 T/C cg12560992 chr17:57184187 TRIM37 0.73 8.7 0.62 1.69e-14 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.517 rs603072 chr10:30755778 C/T cg18806716 chr10:30721971 MAP3K8 0.56 6.76 0.52 4.92e-10 Inflammatory bowel disease; TGCT cis rs56104184 0.725 rs1466896 chr19:49385253 C/G cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2074585 0.647 rs2601178 chr15:90919333 T/C cg22089800 chr15:90895588 ZNF774 0.82 9.04 0.63 2.61e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs35306767 0.903 rs10508208 chr10:910983 C/T cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs2075371 0.796 rs1978504 chr7:134006933 C/T cg11752832 chr7:134001865 SLC35B4 -0.69 -6.15 -0.48 9.86e-9 Mean platelet volume; TGCT cis rs13256369 0.802 rs11249885 chr8:8562008 C/T cg06671706 chr8:8559999 CLDN23 0.33 4.48 0.37 1.65e-5 Obesity-related traits; TGCT cis rs1799949 0.536 rs4793227 chr17:41412250 A/C cg23758822 chr17:41437982 NA 0.68 6.6 0.51 1.06e-9 Menopause (age at onset); TGCT cis rs7267979 1.000 rs401166 chr20:25446308 C/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2832191 0.692 rs2245517 chr21:30357968 C/T cg24692254 chr21:30365293 RNF160 1.01 11.79 0.73 5.45e-22 Dental caries; TGCT cis rs3087591 1.000 rs4541129 chr17:29442878 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 7.29 0.55 3.12e-11 Hip circumference; TGCT cis rs9467773 0.967 rs6456732 chr6:26514445 T/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9379850 0.730 rs9393738 chr6:26620658 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.55 -5.08 -0.42 1.35e-6 Intelligence (multi-trait analysis); TGCT cis rs4713118 0.513 rs149950 chr6:28033039 T/G cg10876282 chr6:28092338 ZSCAN16 0.5 4.6 0.38 1.01e-5 Parkinson's disease; TGCT cis rs9915657 0.773 rs9900977 chr17:70110438 A/G cg06234051 chr17:70120541 SOX9 -0.26 -5.23 -0.43 6.84e-7 Thyroid hormone levels; TGCT cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg05985448 chr10:134359359 INPP5A 0.21 4.5 0.37 1.52e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1344694 0.548 rs12468812 chr2:216905867 C/T cg12620499 chr2:216877984 MREG 0.82 8.57 0.61 3.44e-14 Alcohol dependence; TGCT cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs778371 0.871 rs2675954 chr2:233750627 C/G cg25237894 chr2:233734115 C2orf82 -0.25 -4.53 -0.38 1.37e-5 Schizophrenia; TGCT cis rs2075371 1.000 rs378358 chr7:133970628 A/G cg11752832 chr7:134001865 SLC35B4 0.66 6.11 0.48 1.19e-8 Mean platelet volume; TGCT cis rs939658 0.567 rs11631829 chr15:79446529 C/T cg17916960 chr15:79447300 NA -0.4 -5.65 -0.45 1.03e-7 Refractive error; TGCT cis rs868036 0.681 rs28670272 chr15:68109907 C/T cg05925327 chr15:68127851 NA 0.5 4.85 0.4 3.57e-6 Restless legs syndrome; TGCT cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs5769765 0.865 rs4824108 chr22:50271428 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs7552404 0.691 rs61770550 chr1:76366966 C/T cg10523679 chr1:76189770 ACADM 0.85 7.54 0.56 8.71e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4665809 1.000 rs4665304 chr2:26313406 C/T cg04944784 chr2:26401820 FAM59B -0.68 -6.04 -0.48 1.7e-8 Gut microbiome composition (summer); TGCT cis rs56104184 0.779 rs17272666 chr19:49356294 T/C cg17863274 chr19:49399704 TULP2 -0.45 -5.4 -0.44 3.22e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9611565 0.592 rs5751101 chr22:41828111 C/T cg06481639 chr22:41940642 POLR3H 0.73 6.61 0.51 1.03e-9 Vitiligo; TGCT cis rs2013441 1.000 rs2703794 chr17:20073338 T/C cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs4819852 1.000 rs4819852 chr22:19988167 G/A cg07821417 chr22:19972146 ARVCF 0.2 5.14 0.42 1.04e-6 Pulse pressure; TGCT cis rs524281 0.637 rs7126075 chr11:65940563 T/G cg00563793 chr11:65837595 PACS1 0.56 4.72 0.39 6.28e-6 Electroencephalogram traits; TGCT cis rs3924048 0.574 rs11121925 chr1:12613130 A/C cg00291366 chr1:12616550 NA 0.33 4.95 0.41 2.41e-6 Optic cup area; TGCT cis rs3820068 0.603 rs6429767 chr1:15963334 G/A cg05660106 chr1:15850417 CASP9 0.83 8.19 0.59 2.78e-13 Systolic blood pressure; TGCT cis rs12681288 0.862 rs2600487 chr8:1016903 C/T cg04851639 chr8:1020857 NA -0.4 -7.51 -0.56 9.9e-12 Schizophrenia; TGCT cis rs11931598 0.514 rs10937779 chr4:7039326 G/A cg02503808 chr4:7069936 GRPEL1 0.65 6.65 0.51 8.57e-10 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs68170813 0.559 rs2189501 chr7:106942766 A/T cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs10744422 1.000 rs937766 chr12:123331094 G/T cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs9653442 0.704 rs10211595 chr2:100726476 G/C cg22139774 chr2:100720529 AFF3 -0.42 -7.49 -0.56 1.1e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7208859 0.673 rs216411 chr17:28903493 T/C cg14008862 chr17:28927542 LRRC37B2 -0.76 -4.71 -0.39 6.61e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg21280719 chr6:42927975 GNMT 0.37 4.59 0.38 1.07e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs13082711 0.522 rs515402 chr3:27331022 G/T cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7312774 0.618 rs61061573 chr12:107372758 T/C cg16260113 chr12:107380972 MTERFD3 1.0 5.13 0.42 1.07e-6 Severe influenza A (H1N1) infection; TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg14820908 chr5:178986412 RUFY1 0.61 6.78 0.52 4.37e-10 Lung cancer; TGCT cis rs4819052 0.620 rs421619 chr21:46546115 C/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.53 0.38 1.39e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6570726 1.000 rs405622 chr6:145871897 G/T cg05347473 chr6:146136440 FBXO30 0.5 4.46 0.37 1.82e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7681440 0.904 rs28734152 chr4:90767359 C/T cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs889312 0.500 rs832585 chr5:56125904 T/C cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs1799949 0.965 rs6503726 chr17:41284742 T/C cg10047753 chr17:41438598 NA 0.71 6.47 0.5 2.02e-9 Menopause (age at onset); TGCT cis rs2290416 0.688 rs62522171 chr8:144690832 C/A cg08017634 chr8:144659831 NAPRT1 0.51 4.68 0.39 7.36e-6 Attention deficit hyperactivity disorder; TGCT cis rs1008375 0.966 rs2286773 chr4:17616214 C/A cg10189774 chr4:17578691 LAP3 0.61 5.34 0.43 4.35e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs938554 0.501 rs7671266 chr4:10056376 C/T cg11266682 chr4:10021025 SLC2A9 -0.54 -5.17 -0.42 8.92e-7 Blood metabolite levels; TGCT cis rs227917 1.000 rs10253843 chr7:23684965 C/T cg12601843 chr7:23510954 IGF2BP3 0.59 4.67 0.39 7.83e-6 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs11190604 1.000 rs3750720 chr10:102248884 C/T cg16342193 chr10:102329863 NA -0.42 -5.46 -0.44 2.49e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs911555 0.723 rs6575986 chr14:103886671 G/A cg23461800 chr14:103021989 NA 0.33 4.46 0.37 1.83e-5 Intelligence (multi-trait analysis); TGCT cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg11494091 chr17:61959527 GH2 0.42 7.02 0.53 1.3e-10 Height; TGCT cis rs910316 0.664 rs2098252 chr14:75492732 T/C cg11812906 chr14:75593930 NEK9 0.59 5.59 0.45 1.36e-7 Height; TGCT cis rs1801251 1.000 rs2100053 chr2:233719516 G/T cg25237894 chr2:233734115 C2orf82 -0.33 -5.91 -0.47 3.13e-8 Coronary artery disease; TGCT cis rs7917772 0.502 rs2296583 chr10:104244322 T/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg24675658 chr1:53192096 ZYG11B 0.76 8.75 0.62 1.3e-14 Monocyte count; TGCT cis rs734999 0.588 rs867435 chr1:2523706 C/T cg18854424 chr1:2615690 NA 0.45 5.17 0.42 9.18e-7 Ulcerative colitis; TGCT cis rs3796352 1.000 rs13072395 chr3:52980573 T/C cg07884673 chr3:53033167 SFMBT1 0.63 5.74 0.46 6.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg11644478 chr21:40555479 PSMG1 1.0 10.04 0.67 9.98e-18 Cognitive function; TGCT cis rs6545883 0.929 rs2264100 chr2:61670829 G/A cg15711740 chr2:61764176 XPO1 -0.56 -5.07 -0.41 1.42e-6 Tuberculosis; TGCT cis rs2455799 0.594 rs11128769 chr3:15926230 C/T cg16303742 chr3:15540471 COLQ -0.24 -4.51 -0.38 1.51e-5 Mean platelet volume; TGCT cis rs477895 0.652 rs72920332 chr11:63947071 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 6.5 0.5 1.75e-9 Mean platelet volume; TGCT cis rs7666738 0.822 rs6815312 chr4:99058220 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg03806693 chr22:41940476 POLR3H 1.08 11.99 0.73 1.84e-22 Crohn's disease;Inflammatory bowel disease; TGCT cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.41 2.55e-6 Obesity-related traits; TGCT trans rs629535 0.590 rs62513427 chr8:70138891 A/T cg21567404 chr3:27674614 NA -0.52 -7.76 -0.57 2.74e-12 Dupuytren's disease; TGCT cis rs60871478 0.636 rs55663559 chr7:884057 G/A cg00475322 chr7:917719 C7orf20 0.49 4.79 0.39 4.72e-6 Cerebrospinal P-tau181p levels; TGCT cis rs362272 0.545 rs2236052 chr4:3318413 C/T cg06533319 chr4:3265114 C4orf44 0.26 5.32 0.43 4.74e-7 Serum sulfate level; TGCT cis rs35306767 0.855 rs61830931 chr10:932497 T/C cg26597838 chr10:835615 NA 0.81 12.42 0.74 1.61e-23 Eosinophil percentage of granulocytes; TGCT cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg20607798 chr8:58055168 NA 0.66 5.58 0.45 1.46e-7 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.808 rs7599799 chr2:43685493 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.19 -0.42 8.37e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7553864 0.614 rs4559475 chr1:87614236 T/C cg17420885 chr1:87600446 LOC339524 -0.37 -4.89 -0.4 3.04e-6 Smoking behavior; TGCT cis rs3008870 1.000 rs3008854 chr1:67385951 T/C cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs79976124 0.800 rs10944857 chr6:66637078 C/T cg07460842 chr6:66804631 NA 0.58 5.12 0.42 1.14e-6 Type 2 diabetes; TGCT cis rs12711979 0.509 rs13000873 chr2:3823705 T/C cg17052675 chr2:3827356 NA -0.55 -12.73 -0.75 2.94e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs3772130 0.545 rs7340674 chr3:121574215 T/C cg20356878 chr3:121714668 ILDR1 0.38 4.84 0.4 3.71e-6 Cognitive performance; TGCT trans rs941408 1.000 rs1736180 chr19:2796021 C/T cg19676328 chr12:49525230 TUBA1B -0.74 -7.25 -0.55 3.98e-11 Total cholesterol levels; TGCT cis rs2677744 0.657 rs11073961 chr15:91483392 A/G cg23684204 chr15:91497937 RCCD1 0.32 4.71 0.39 6.47e-6 Attention deficit hyperactivity disorder; TGCT cis rs1475911 1.000 rs2839466 chr21:43512324 A/G cg14562523 chr21:43528734 C21orf128;UMODL1 0.24 4.73 0.39 5.99e-6 IgG glycosylation; TGCT cis rs2997457 1.000 rs2997457 chr1:26343112 A/G cg07766612 chr1:26372887 SLC30A2 -0.64 -4.78 -0.39 4.93e-6 Facial morphology (factor 16); TGCT cis rs1801251 0.964 rs10933411 chr2:233706847 A/G cg25237894 chr2:233734115 C2orf82 -0.33 -5.94 -0.47 2.71e-8 Coronary artery disease; TGCT cis rs2820315 1.000 rs2820312 chr1:201869257 G/A cg12730843 chr1:201915899 LMOD1 -0.27 -4.73 -0.39 6.07e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs78487399 0.808 rs13405776 chr2:43739121 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7635838 0.617 rs347590 chr3:11289561 G/A cg00170343 chr3:11313890 ATG7 0.65 6.44 0.5 2.4e-9 HDL cholesterol; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg24846343 chr22:24311635 DDTL 0.19 4.47 0.37 1.77e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6840360 0.692 rs1838043 chr4:152411462 T/C cg17479576 chr4:152424074 FAM160A1 -0.5 -5.03 -0.41 1.65e-6 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.897 rs67455495 chr4:17665238 A/T cg18681998 chr4:17616180 MED28 -0.94 -9.83 -0.66 3.2e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2276314 1.000 rs58054756 chr18:33554053 G/C cg05985134 chr18:33552581 C18orf21 0.54 4.82 0.4 4.12e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs78487399 0.808 rs17030845 chr2:43687879 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.77 0.39 5.16e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs854765 0.647 rs741782 chr17:18019712 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.71 7.37 0.55 2.15e-11 Total body bone mineral density; TGCT cis rs7647973 0.925 rs6446256 chr3:49224210 A/G cg05785598 chr3:49045655 WDR6 0.38 4.68 0.39 7.48e-6 Menarche (age at onset); TGCT cis rs7647973 1.000 rs9871024 chr3:49554241 T/C cg07636037 chr3:49044803 WDR6 -0.65 -5.35 -0.43 4.01e-7 Menarche (age at onset); TGCT cis rs4455778 0.580 rs7808082 chr7:49124973 T/C cg26309511 chr7:48887640 NA 0.51 6.62 0.51 9.97e-10 Lung cancer in never smokers; TGCT cis rs7586879 0.575 rs6706316 chr2:25128351 C/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs861020 0.771 rs1962735 chr1:210012102 A/G cg05527609 chr1:210001259 C1orf107 0.99 9.24 0.64 8.92e-16 Orofacial clefts; TGCT cis rs6725041 0.792 rs4638732 chr2:213090070 A/C cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs9910055 0.529 rs228767 chr17:42188311 C/G cg19774624 chr17:42201019 HDAC5 0.75 7.13 0.54 7.4e-11 Total body bone mineral density; TGCT cis rs644799 0.526 rs542509 chr11:95641602 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.47 5.01 0.41 1.87e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1552244 0.554 rs13079240 chr3:10047246 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs6815814 0.898 rs2174284 chr4:38859339 C/T cg02016764 chr4:38805732 TLR1 -0.36 -5.4 -0.44 3.33e-7 Breast cancer; TGCT cis rs1534166 0.647 rs9853615 chr3:133519981 C/T cg16414030 chr3:133502952 NA -0.46 -6.0 -0.47 2.01e-8 Alcohol consumption (transferrin glycosylation); TGCT cis rs9611565 0.765 rs727563 chr22:41867377 C/T cg02107564 chr22:41488750 EP300 0.56 4.61 0.38 9.88e-6 Vitiligo; TGCT cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg20607798 chr8:58055168 NA 0.65 5.43 0.44 2.86e-7 Developmental language disorder (linguistic errors); TGCT cis rs7264396 0.635 rs6121073 chr20:34457513 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs11122272 0.766 rs2790872 chr1:231540543 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -6.09 -0.48 1.32e-8 Hemoglobin concentration; TGCT cis rs6438424 0.521 rs12634615 chr3:117748947 A/G cg15509235 chr3:117715573 NA 0.54 5.37 0.43 3.79e-7 Menarche (age at onset); TGCT cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg12310025 chr6:25882481 NA -0.65 -5.67 -0.45 9.54e-8 Intelligence (multi-trait analysis); TGCT cis rs11030122 0.661 rs12290747 chr11:3939650 T/C cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs17376456 0.542 rs10061069 chr5:93071630 G/C cg21475434 chr5:93447410 FAM172A 0.64 6.04 0.48 1.69e-8 Diabetic retinopathy; TGCT cis rs7674212 0.570 rs2711899 chr4:104062414 T/C cg16532752 chr4:104119610 CENPE -0.66 -6.02 -0.48 1.86e-8 Type 2 diabetes; TGCT cis rs3784262 1.000 rs11855259 chr15:58249377 C/G cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.76 -0.57 2.71e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4332037 0.552 rs11773627 chr7:2002733 A/G cg25834613 chr7:1915315 MAD1L1 -0.46 -4.73 -0.39 6.06e-6 Bipolar disorder; TGCT cis rs2046867 0.862 rs6766747 chr3:72856551 T/C cg25664220 chr3:72788482 NA -0.56 -7.05 -0.53 1.1e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs11644362 0.966 rs1433747 chr16:12992147 C/A cg06890432 chr16:12997467 SHISA9 -0.6 -6.35 -0.5 3.77e-9 Positive affect;Subjective well-being; TGCT cis rs6977660 0.714 rs17141882 chr7:19790217 C/T cg07541023 chr7:19748670 TWISTNB 0.85 4.84 0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs12580194 0.593 rs58254871 chr12:55750281 G/A cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs2708977 0.965 rs13019986 chr2:97243058 C/T cg01950434 chr2:97203154 ARID5A 0.64 5.85 0.47 4.09e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7772486 0.875 rs9373485 chr6:146401429 A/T cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg06558623 chr16:89946397 TCF25 0.57 6.89 0.53 2.56e-10 Skin colour saturation; TGCT cis rs506338 0.517 rs530775 chr11:64426933 A/G cg19395706 chr11:64412079 NRXN2 0.49 5.98 0.47 2.2e-8 Body mass index;Urate levels; TGCT cis rs6450176 0.909 rs11742688 chr5:53291081 C/T ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.09e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs35160687 0.901 rs12999029 chr2:86502913 G/A cg03171300 chr2:86307199 POLR1A 0.32 5.49 0.44 2.18e-7 Night sleep phenotypes; TGCT cis rs3213545 0.700 rs2260399 chr12:121469653 C/T cg15155738 chr12:121454335 C12orf43 0.47 4.61 0.38 9.85e-6 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs1475911 0.708 rs66994219 chr21:43521647 G/A cg19766460 chr21:43528205 UMODL1;C21orf128 0.65 9.36 0.64 4.41e-16 IgG glycosylation; TGCT cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg23708337 chr7:1209742 NA 0.61 5.52 0.44 1.89e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1005224 0.853 rs9323616 chr14:76151697 T/C cg25116370 chr14:76127843 TTLL5;C14orf1 -0.54 -4.72 -0.39 6.23e-6 Large artery stroke; TGCT cis rs40363 1.000 rs1690444 chr16:3518350 G/A cg00484396 chr16:3507460 NAT15 0.43 5.04 0.41 1.57e-6 Tuberculosis; TGCT cis rs28493229 0.708 rs10407650 chr19:41160970 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg27535305 chr1:53392650 SCP2 -0.24 -4.69 -0.39 6.96e-6 Monocyte count; TGCT cis rs428668 0.681 rs428064 chr5:150696498 G/A cg11125805 chr5:150678162 SLC36A3 0.27 6.12 0.48 1.12e-8 Skin aging (microtopography measurement); TGCT cis rs7044106 0.791 rs4837792 chr9:123483559 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.55 0.51 1.37e-9 Hip circumference adjusted for BMI; TGCT cis rs12780845 0.505 rs10795460 chr10:17244253 A/G cg01003015 chr10:17271136 VIM -0.59 -5.45 -0.44 2.65e-7 Homocysteine levels; TGCT cis rs8032315 0.895 rs4932370 chr15:91404705 A/G cg05211768 chr15:91427848 FES -0.52 -5.22 -0.42 7.17e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12134245 0.742 rs17501381 chr1:92003919 A/G cg25838465 chr1:92012736 NA -0.41 -6.57 -0.51 1.23e-9 Breast cancer; TGCT cis rs7714584 1.000 rs11746560 chr5:150185925 T/G cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs6570726 0.935 rs453609 chr6:145812332 T/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.16e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs11578119 0.772 rs1333142 chr1:170466454 A/G cg09767346 chr1:170501363 GORAB -0.67 -5.36 -0.43 3.85e-7 Male-pattern baldness; TGCT cis rs2013441 1.000 rs2703782 chr17:20144799 A/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs12681287 1.000 rs12681287 chr8:87269536 A/C cg27223183 chr8:87520930 FAM82B 0.78 5.7 0.46 8.18e-8 Caudate activity during reward; TGCT cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg04546413 chr19:29218101 NA 0.82 7.84 0.58 1.72e-12 Methadone dose in opioid dependence; TGCT cis rs1629083 0.875 rs11216819 chr11:118084980 G/A cg16594165 chr11:118135105 MPZL2 -0.33 -4.52 -0.38 1.4e-5 Lung cancer; TGCT cis rs2346177 0.844 rs34791442 chr2:46655169 T/C cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.63 -0.38 9.01e-6 HDL cholesterol; TGCT cis rs1475911 1.000 rs2839466 chr21:43512324 A/G cg24372256 chr21:43528868 UMODL1;C21orf128 0.25 4.55 0.38 1.25e-5 IgG glycosylation; TGCT cis rs28785552 0.769 rs7253672 chr19:53243212 G/C cg04754360 chr19:53238445 ZNF611 -0.64 -5.24 -0.43 6.75e-7 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.47 -0.37 1.72e-5 Bipolar disorder; TGCT cis rs911555 0.755 rs2403192 chr14:103974235 C/T cg12935359 chr14:103987150 CKB -0.33 -4.66 -0.39 7.91e-6 Intelligence (multi-trait analysis); TGCT cis rs10114408 0.760 rs35590214 chr9:96643844 A/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs981844 0.816 rs56109239 chr4:154726500 A/G cg14289246 chr4:154710475 SFRP2 1.02 8.96 0.63 4.15e-15 Response to statins (LDL cholesterol change); TGCT cis rs8180040 0.620 rs11709660 chr3:47074927 G/A cg27129171 chr3:47204927 SETD2 -0.71 -8.51 -0.61 4.8e-14 Colorectal cancer; TGCT cis rs739496 0.615 rs12427276 chr12:112113508 G/A cg10833066 chr12:111807467 FAM109A 0.37 4.79 0.39 4.76e-6 Platelet count; TGCT cis rs7647973 1.000 rs62259947 chr3:49439924 T/C cg06212747 chr3:49208901 KLHDC8B -0.59 -4.68 -0.39 7.32e-6 Menarche (age at onset); TGCT cis rs10883723 0.810 rs10786669 chr10:104256094 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.74 0.62 1.4e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7267979 1.000 rs453329 chr20:25440593 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7647973 0.587 rs10452032 chr3:49680973 G/A cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs68170813 0.559 rs58663672 chr7:106949444 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs9905704 0.647 rs8077332 chr17:57105223 A/G cg05425664 chr17:57184151 TRIM37 -0.68 -5.65 -0.45 1.06e-7 Testicular germ cell tumor; TGCT trans rs1496653 0.602 rs35928592 chr3:23389659 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs11676855 1.000 rs11676855 chr2:235900171 C/T cg14917874 chr2:235941519 SH3BP4 -0.22 -4.82 -0.4 4.19e-6 Dialysis-related mortality; TGCT cis rs4319547 0.619 rs7973869 chr12:122874284 G/C cg08088222 chr12:122070432 ORAI1 0.25 4.49 0.37 1.58e-5 Body mass index; TGCT cis rs9911578 1.000 rs8067571 chr17:56868856 C/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.567 rs6120815 chr20:30184866 T/C cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs12477438 0.520 rs6542864 chr2:99725223 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs2562456 0.755 rs2914646 chr19:21637161 A/C cg01304269 chr19:21688519 ZNF429 -0.58 -4.61 -0.38 1e-5 Pain; TGCT cis rs1519814 0.592 rs4870969 chr8:121006548 G/A cg22335954 chr8:121166405 COL14A1 -0.36 -4.48 -0.37 1.67e-5 Breast cancer; TGCT cis rs2594989 0.943 rs9830784 chr3:11434605 A/G cg00170343 chr3:11313890 ATG7 0.78 5.36 0.43 3.92e-7 Circulating chemerin levels; TGCT cis rs7412746 0.658 rs59024312 chr1:150909005 T/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs4478037 0.822 rs9817393 chr3:33117069 A/G cg19404215 chr3:33155277 CRTAP 1.27 6.16 0.48 9.36e-9 Major depressive disorder; TGCT cis rs9902453 0.967 rs12602065 chr17:28482488 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg10074409 chr1:209979377 IRF6 0.51 5.89 0.47 3.45e-8 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs9517313 0.591 rs17574543 chr13:99172893 G/A cg20487152 chr13:99095054 FARP1 -0.29 -5.39 -0.44 3.39e-7 Neuroticism; TGCT cis rs6912958 0.712 rs4587138 chr6:88356915 G/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs7103411 0.592 rs11030087 chr11:27646246 T/C cg10635145 chr11:27742435 BDNF 0.32 4.47 0.37 1.72e-5 Menarche (age at onset);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; TGCT cis rs2070488 1.000 rs1002675 chr3:38445226 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 9.76 0.66 4.77e-17 Electrocardiographic conduction measures; TGCT cis rs7523273 0.606 rs2488254 chr1:207941539 A/G cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT trans rs916888 0.610 rs199446 chr17:44813169 G/A cg22433210 chr17:43662623 NA -0.94 -7.99 -0.58 7.87e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9811920 0.695 rs793497 chr3:99505610 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 4.73 0.39 6.09e-6 Axial length; TGCT cis rs10256972 0.669 rs10229964 chr7:1051776 A/G cg16145915 chr7:1198662 ZFAND2A -0.47 -5.47 -0.44 2.35e-7 Longevity;Endometriosis; TGCT cis rs7819412 0.522 rs4642600 chr8:11013025 C/A cg21775007 chr8:11205619 TDH -0.52 -4.63 -0.38 8.99e-6 Triglycerides; TGCT cis rs2075671 0.810 rs12531792 chr7:100280624 G/A cg20848291 chr7:100343083 ZAN -0.52 -4.56 -0.38 1.21e-5 Other erythrocyte phenotypes; TGCT cis rs1018836 0.739 rs4734247 chr8:91569144 A/G cg16814680 chr8:91681699 NA -0.8 -8.57 -0.61 3.46e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10197940 0.578 rs2432957 chr2:152287897 A/C cg06191203 chr2:152266755 RIF1 -0.58 -4.92 -0.4 2.7e-6 Lung cancer; TGCT cis rs68190844 1 rs68190844 chr17:4568953 CTA/C cg23387401 chr17:4582204 PELP1 -0.31 -4.63 -0.38 8.97e-6 Eosinophil percentage of white cells; TGCT cis rs1372520 0.684 rs356162 chr4:90697157 T/C cg14346243 chr4:90757452 SNCA 0.62 5.29 0.43 5.26e-7 Neuroticism; TGCT cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg10047753 chr17:41438598 NA 0.96 9.86 0.66 2.71e-17 Menopause (age at onset); TGCT cis rs4319547 1.000 rs10998 chr12:122989412 G/A cg23029597 chr12:123009494 RSRC2 -0.31 -4.99 -0.41 1.96e-6 Body mass index; TGCT cis rs9467773 1.000 rs3736781 chr6:26505362 G/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg15687855 chr3:44754131 ZNF502 -0.55 -6.8 -0.52 3.9e-10 Depressive symptoms; TGCT cis rs12497850 0.931 rs9840684 chr3:48893780 T/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs853679 0.517 rs4713145 chr6:28106827 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs1113500 0.787 rs11185266 chr1:108642664 G/A cg22161131 chr1:109420278 GPSM2 0.49 4.45 0.37 1.88e-5 Growth-regulated protein alpha levels; TGCT cis rs3741151 0.892 rs76854106 chr11:73027110 G/A cg17517138 chr11:73019481 ARHGEF17 0.9 4.51 0.38 1.45e-5 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT trans rs6951245 0.580 rs78894484 chr7:1138721 T/G cg13565492 chr6:43139072 SRF -0.82 -7.72 -0.57 3.43e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9910055 0.529 rs2523161 chr17:42179405 C/T cg13607699 chr17:42295918 UBTF -0.61 -5.09 -0.42 1.32e-6 Total body bone mineral density; TGCT cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg06481639 chr22:41940642 POLR3H -0.75 -6.47 -0.5 2.1e-9 Vitiligo; TGCT cis rs13177918 0.677 rs13183077 chr5:149826572 G/A cg14059543 chr5:149831962 NA -0.71 -9.35 -0.64 4.68e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9486715 0.867 rs2223238 chr6:96871855 G/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs1552244 0.816 rs17050701 chr3:10041554 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs2549003 0.966 rs2070730 chr5:131819800 G/A cg21138405 chr5:131827807 IRF1 0.19 4.79 0.4 4.64e-6 Asthma (sex interaction); TGCT cis rs7772486 0.654 rs6906402 chr6:146089307 C/G cg23711669 chr6:146136114 FBXO30 -0.92 -10.41 -0.68 1.3e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs74233809 1.000 rs112390216 chr10:104741031 C/T cg05855489 chr10:104503620 C10orf26 0.74 4.44 0.37 1.96e-5 Birth weight; TGCT cis rs17376456 0.504 rs6898507 chr5:93082343 C/T cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT cis rs6460942 0.908 rs78682952 chr7:12284886 C/A cg06484146 chr7:12443880 VWDE -0.57 -4.9 -0.4 2.91e-6 Coronary artery disease; TGCT cis rs610932 0.517 rs688460 chr11:59986710 C/T cg18570331 chr11:60101691 MS4A6E 0.53 4.86 0.4 3.5e-6 Alzheimer's disease; TGCT cis rs6088580 0.634 rs6059860 chr20:33063830 A/C cg06115741 chr20:33292138 TP53INP2 0.55 4.68 0.39 7.39e-6 Glomerular filtration rate (creatinine); TGCT cis rs12042938 0.507 rs1765778 chr1:231732356 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.62 -6.16 -0.48 9.54e-9 Neuranatomic and neurocognitive phenotypes; TGCT cis rs10992471 0.756 rs10992319 chr9:95127895 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.26 -0.49 5.73e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7647973 0.506 rs11920251 chr3:49356671 C/T cg06212747 chr3:49208901 KLHDC8B 0.53 4.58 0.38 1.13e-5 Menarche (age at onset); TGCT cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg10047753 chr17:41438598 NA 0.96 9.62 0.65 1.04e-16 Menopause (age at onset); TGCT cis rs4478037 0.642 rs77202692 chr3:33115776 A/C cg19404215 chr3:33155277 CRTAP 1.2 6.68 0.51 7.34e-10 Major depressive disorder; TGCT cis rs7647973 0.626 rs1491985 chr3:49739507 G/C cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs7666738 0.830 rs62321597 chr4:99014221 C/A cg17366294 chr4:99064904 C4orf37 0.66 6.75 0.52 5.04e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.545 rs5758432 chr22:42111693 T/C cg06634786 chr22:41940651 POLR3H 0.89 8.68 0.61 1.88e-14 Vitiligo; TGCT cis rs8031584 0.651 rs28664821 chr15:31172323 G/A cg08109568 chr15:31115862 NA 0.37 4.91 0.4 2.8e-6 Huntington's disease progression; TGCT cis rs1401999 0.565 rs4912515 chr3:183653718 A/G cg01324343 chr3:183735012 ABCC5 0.49 5.58 0.45 1.46e-7 Anterior chamber depth; TGCT cis rs7681440 0.838 rs1348224 chr4:90761946 G/A cg26578617 chr4:90757533 SNCA -0.49 -5.12 -0.42 1.15e-6 Dementia with Lewy bodies; TGCT cis rs10927875 0.541 rs1048334 chr1:16340761 T/C cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg06481639 chr22:41940642 POLR3H 0.75 6.86 0.52 2.84e-10 Vitiligo; TGCT cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg06481639 chr22:41940642 POLR3H -0.61 -5.49 -0.44 2.17e-7 Vitiligo; TGCT cis rs9611565 0.525 rs9611549 chr22:41705909 C/G cg13695892 chr22:41940480 POLR3H -0.67 -6.28 -0.49 5.18e-9 Vitiligo; TGCT cis rs7086627 0.515 rs10887895 chr10:82210011 A/G cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs17376456 0.569 rs7701114 chr5:93096028 T/C cg25358565 chr5:93447407 FAM172A 0.76 6.68 0.51 7.23e-10 Diabetic retinopathy; TGCT cis rs3749237 1.000 rs6804655 chr3:49738945 C/T cg03060546 chr3:49711283 APEH 0.74 7.6 0.56 6.37e-12 Resting heart rate; TGCT cis rs514406 0.505 rs447581 chr1:53177098 T/C cg16325326 chr1:53192061 ZYG11B 0.86 12.25 0.74 4.3e-23 Monocyte count; TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg06374610 chr10:50328992 NA -0.83 -6.79 -0.52 4.09e-10 Follicular lymphoma; TGCT cis rs807669 0.504 rs8141941 chr22:19166263 G/A cg02655711 chr22:19163373 SLC25A1 0.27 5.16 0.42 9.53e-7 Metabolite levels; TGCT cis rs1729951 0.575 rs10935213 chr3:136693459 A/G cg12473912 chr3:136751656 NA 0.39 6.16 0.48 9.31e-9 Neuroticism; TGCT cis rs853679 0.546 rs34295134 chr6:27828151 T/A cg10876282 chr6:28092338 ZSCAN16 0.75 4.45 0.37 1.88e-5 Depression; TGCT cis rs1348850 0.872 rs2084233 chr2:178331206 G/A cg22681709 chr2:178499509 PDE11A -0.36 -4.71 -0.39 6.46e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1915146 0.967 rs7086481 chr10:126844523 A/T cg10402121 chr10:126487101 NA -0.25 -4.63 -0.38 9.07e-6 Menarche (age at onset); TGCT cis rs6582630 0.519 rs11520262 chr12:38333051 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.19 0.54 5.37e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7659604 0.521 rs4833773 chr4:122689245 C/T cg06713675 chr4:122721982 EXOSC9 0.36 4.57 0.38 1.16e-5 Type 2 diabetes; TGCT cis rs9467711 0.722 rs35825164 chr6:26117404 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.57 -4.54 -0.38 1.33e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2404602 0.563 rs12914005 chr15:76765667 A/G cg26408565 chr15:76604113 ETFA -0.37 -5.1 -0.42 1.21e-6 Blood metabolite levels; TGCT cis rs10197940 0.662 rs10173699 chr2:152281561 C/G cg06191203 chr2:152266755 RIF1 0.79 7.27 0.55 3.55e-11 Lung cancer; TGCT cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs5769707 0.967 rs1018812 chr22:50010073 C/T cg20744362 chr22:50050164 C22orf34 0.29 4.74 0.39 5.83e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs12477438 0.520 rs11883676 chr2:99800814 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs6952809 0.532 rs2057840 chr7:2432797 C/G cg23289794 chr7:2394357 EIF3B -0.8 -6.81 -0.52 3.79e-10 Multiple sclerosis; TGCT cis rs9796 0.636 rs1983400 chr15:41373029 T/C cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.77 -0.52 4.58e-10 Menopause (age at onset); TGCT cis rs5750830 0.594 rs9611166 chr22:39775268 T/C cg02038168 chr22:39784481 NA -0.64 -5.48 -0.44 2.32e-7 Intelligence (multi-trait analysis); TGCT cis rs72700829 0.518 rs34755378 chr1:150242340 G/A cg18798344 chr1:149336151 NA 0.56 4.5 0.37 1.52e-5 Schizophrenia; TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg05457628 chr5:178986728 RUFY1 0.44 4.67 0.39 7.56e-6 Lung cancer; TGCT cis rs17102423 0.896 rs8004805 chr14:65579720 T/C cg11161011 chr14:65562177 MAX -0.49 -6.47 -0.5 2.02e-9 Obesity-related traits; TGCT cis rs798554 0.679 rs2527681 chr7:2892384 A/T cg13628971 chr7:2884303 GNA12 0.62 5.24 0.43 6.8e-7 Height; TGCT cis rs1348850 0.846 rs4893962 chr2:178421106 A/G cg22681709 chr2:178499509 PDE11A -0.38 -5.24 -0.43 6.57e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2153535 0.580 rs9328488 chr6:8529411 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg23205692 chr1:25664452 TMEM50A 0.53 5.48 0.44 2.32e-7 Erythrocyte sedimentation rate; TGCT cis rs3812831 0.543 rs389108 chr13:114925389 A/G cg06611532 chr13:114900021 NA 0.34 6.16 0.48 9.55e-9 Schizophrenia; TGCT cis rs13191362 0.872 rs13213421 chr6:163203805 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.76 0.52 4.71e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.791 rs10033994 chr4:98969582 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs2143355 chr6:8517856 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs758117 0.744 rs7312107 chr12:2523370 C/T cg07128330 chr12:2921958 ITFG2 -0.44 -4.45 -0.37 1.91e-5 Schizophrenia; TGCT cis rs10875595 0.836 rs1363453 chr5:140657864 G/A cg20560182 chr5:140700478 TAF7 -0.66 -5.06 -0.41 1.49e-6 Pulmonary function decline; TGCT cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.56 -5.57 -0.45 1.52e-7 Electroencephalogram traits; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg21548813 chr6:291882 DUSP22 -0.71 -7.45 -0.56 1.36e-11 Menopause (age at onset); TGCT cis rs2070488 1.000 rs13074160 chr3:38455650 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 9.06e-17 Electrocardiographic conduction measures; TGCT cis rs910316 0.967 rs10142770 chr14:75525449 G/A cg11812906 chr14:75593930 NEK9 0.73 7.08 0.54 9.26e-11 Height; TGCT cis rs28595532 0.920 rs114564223 chr4:119729953 A/G cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs9653442 0.564 rs4851261 chr2:100786717 A/G cg22139774 chr2:100720529 AFF3 -0.36 -5.69 -0.46 8.67e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs875971 0.929 rs6970860 chr7:65976634 A/G cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs514406 0.861 rs1749907 chr1:53259658 C/T cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs60871478 0.636 rs4276575 chr7:900035 C/T cg00475322 chr7:917719 C7orf20 0.49 4.87 0.4 3.3e-6 Cerebrospinal P-tau181p levels; TGCT cis rs67311347 1.000 rs2887995 chr3:40409029 C/G cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs7829975 0.742 rs1533059 chr8:8684953 A/G cg08975724 chr8:8085496 FLJ10661 -0.54 -5.03 -0.41 1.71e-6 Mood instability; TGCT cis rs9291683 0.588 rs13121211 chr4:9999539 A/G cg00071950 chr4:10020882 SLC2A9 0.71 9.08 0.63 2.11e-15 Bone mineral density; TGCT cis rs12142240 0.731 rs12385693 chr1:46818921 A/C cg00530320 chr1:46809349 NSUN4 0.25 4.7 0.39 6.79e-6 Menopause (age at onset); TGCT cis rs7659604 0.540 rs11098643 chr4:122701507 C/A cg19748678 chr4:122722346 EXOSC9 -0.59 -5.86 -0.47 3.97e-8 Type 2 diabetes; TGCT cis rs2486012 1.000 rs1766964 chr1:44381847 T/C cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs864643 0.773 rs13064980 chr3:39545464 A/G cg14968361 chr3:39543547 MOBP 0.43 4.54 0.38 1.3e-5 Attention deficit hyperactivity disorder; TGCT cis rs11711311 0.955 rs12634241 chr3:113397685 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -6.88 -0.53 2.6200000000000003e-10 IgG glycosylation; TGCT cis rs17345786 0.861 rs11711808 chr3:101235101 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.43 0.6 7.33e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.918 rs6002351 chr22:41757223 C/T cg17554472 chr22:41940697 POLR3H -0.45 -4.91 -0.4 2.84e-6 Vitiligo; TGCT cis rs6570726 0.791 rs414600 chr6:145879606 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.671 rs252897 chr5:56223000 G/A cg12311346 chr5:56204834 C5orf35 -0.64 -6.98 -0.53 1.57e-10 Initial pursuit acceleration; TGCT cis rs2404602 0.716 rs4886817 chr15:76877702 C/T cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.08e-6 Blood metabolite levels; TGCT cis rs7772486 0.625 rs2050027 chr6:146116113 C/G cg13319975 chr6:146136371 FBXO30 0.5 4.62 0.38 9.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9318086 0.935 rs2025701 chr13:24440581 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.67 6.78 0.52 4.27e-10 Myopia (pathological); TGCT cis rs11190604 0.767 rs3750723 chr10:102172989 T/C cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.5e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10186029 0.676 rs4673720 chr2:213941581 G/A cg08319019 chr2:214017104 IKZF2 0.63 5.94 0.47 2.67e-8 Systemic sclerosis; TGCT cis rs17155006 0.702 rs399290 chr7:107725977 T/C cg05962710 chr7:107745446 LAMB4 -0.18 -4.52 -0.38 1.4e-5 Pneumococcal bacteremia; TGCT cis rs4642101 0.793 rs3889513 chr3:12844070 G/A cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs17331151 0.573 rs11718060 chr3:52875546 G/A cg27565382 chr3:53032988 SFMBT1 0.47 5.82 0.46 4.71e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs5769765 1.000 rs34774661 chr22:50267508 C/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs3617 0.625 rs11922961 chr3:52868610 T/C cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs910316 1.000 rs12590452 chr14:75548756 T/C cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.61 0.51 1.05e-9 Bipolar disorder; TGCT cis rs4595586 0.545 rs4411311 chr12:39363612 C/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT trans rs9329221 0.617 rs615632 chr8:9796321 C/T cg15556689 chr8:8085844 FLJ10661 -0.81 -8.45 -0.6 6.76e-14 Neuroticism; TGCT cis rs7267979 1.000 rs2257808 chr20:25266450 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62064224 0.509 rs2302276 chr17:30791503 C/T cg18200150 chr17:30822561 MYO1D 0.42 5.02 0.41 1.77e-6 Schizophrenia; TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg27535305 chr1:53392650 SCP2 -0.28 -5.93 -0.47 2.85e-8 Monocyte count; TGCT cis rs514406 0.861 rs505444 chr1:53251860 C/T cg01802117 chr1:53393560 SCP2 -0.41 -4.98 -0.41 2.12e-6 Monocyte count; TGCT cis rs4930561 1.000 rs10896298 chr11:67931459 C/T cg04465784 chr11:67976953 SUV420H1 -0.34 -4.49 -0.37 1.62e-5 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg23172400 chr8:95962367 TP53INP1 -0.4 -6.56 -0.51 1.33e-9 Type 2 diabetes; TGCT cis rs1005277 0.579 rs2472176 chr10:38382921 T/C cg25427524 chr10:38739819 LOC399744 -0.4 -8.2 -0.59 2.5e-13 Extrinsic epigenetic age acceleration; TGCT cis rs10791097 0.694 rs4436551 chr11:130755739 A/G cg05962950 chr11:130786565 SNX19 -0.89 -11.41 -0.72 4.79e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9362426 0.708 rs7753821 chr6:88100010 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.45 4.98 0.41 2.07e-6 Depressive episodes in bipolar disorder; TGCT cis rs12780845 0.540 rs2273736 chr10:17195428 G/C cg01003015 chr10:17271136 VIM -0.51 -4.65 -0.39 8.46e-6 Homocysteine levels; TGCT cis rs13108904 0.539 rs13145722 chr4:1338422 T/A cg03303774 chr4:1407052 NA 0.38 6.07 0.48 1.45e-8 Obesity-related traits; TGCT cis rs9653442 0.609 rs2576678 chr2:100704810 T/C cg22139774 chr2:100720529 AFF3 -0.43 -7.75 -0.57 2.79e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs7611238 0.583 rs13317782 chr3:195153635 C/T cg27323046 chr3:195102265 ACAP2 0.33 4.44 0.37 1.96e-5 Body mass index; TGCT cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg06481639 chr22:41940642 POLR3H -0.68 -5.87 -0.47 3.77e-8 Vitiligo; TGCT cis rs1348850 0.567 rs3770012 chr2:178538023 A/G cg22681709 chr2:178499509 PDE11A 0.48 6.24 0.49 6.25e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs274567 0.501 rs581968 chr5:131710202 G/A cg24060327 chr5:131705240 SLC22A5 0.78 8.46 0.61 6.22e-14 Blood metabolite levels; TGCT cis rs11673344 0.504 rs1667377 chr19:37491868 G/A cg08039142 chr19:36980659 ZNF566 0.59 5.58 0.45 1.41e-7 Obesity-related traits; TGCT cis rs10088262 0.629 rs7827665 chr8:124804190 G/A cg20713898 chr8:124780851 FAM91A1 -0.84 -7.19 -0.54 5.3e-11 Pancreatic cancer; TGCT cis rs7246657 0.639 rs12459015 chr19:38083189 T/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs782590 0.967 rs35504023 chr2:55806503 C/T cg18811423 chr2:55921094 PNPT1 -0.65 -6.93 -0.53 2.02e-10 Metabolic syndrome; TGCT cis rs8177253 1.000 rs3811647 chr3:133484029 G/A cg20276088 chr3:133502917 NA -0.24 -5.02 -0.41 1.74e-6 Iron status biomarkers; TGCT cis rs4664308 1.000 rs17341301 chr2:160902420 G/A cg03641300 chr2:160917029 PLA2R1 -0.27 -6.54 -0.51 1.46e-9 Idiopathic membranous nephropathy; TGCT cis rs2932538 0.883 rs6537740 chr1:113080084 T/G cg22162597 chr1:113214053 CAPZA1 0.28 5.93 0.47 2.84e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.42 5.78 0.46 5.68e-8 Lymphocyte counts; TGCT cis rs736408 0.812 rs746694 chr3:52826620 C/T cg10802521 chr3:52805072 NEK4 -0.68 -7.79 -0.57 2.28e-12 Bipolar disorder; TGCT cis rs9467711 0.516 rs501220 chr6:25873025 C/A cg03264133 chr6:25882463 NA -0.7 -4.71 -0.39 6.45e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12220238 1.000 rs10824112 chr10:75969003 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs6570726 0.818 rs952405 chr6:145925952 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.5 -0.37 1.53e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs57994353 0.568 rs10870151 chr9:139309584 G/A cg13741927 chr9:139327495 INPP5E -0.24 -5.42 -0.44 2.99e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs801193 0.839 rs6968619 chr7:66068867 T/C cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs7818688 0.697 rs75349998 chr8:95990918 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs60871478 0.636 rs7792072 chr7:886239 C/T cg00475322 chr7:917719 C7orf20 0.5 4.87 0.4 3.37e-6 Cerebrospinal P-tau181p levels; TGCT cis rs734999 0.870 rs2985858 chr1:2483298 C/G cg18854424 chr1:2615690 NA 0.49 5.88 0.47 3.6e-8 Ulcerative colitis; TGCT cis rs2836950 0.545 rs2836956 chr21:40623018 C/G cg11890956 chr21:40555474 PSMG1 0.68 6.58 0.51 1.17e-9 Menarche (age at onset); TGCT cis rs62244186 0.627 rs3935212 chr3:44460954 G/A cg10108389 chr3:44770937 ZNF501 -0.46 -4.7 -0.39 6.86e-6 Depressive symptoms; TGCT cis rs7666738 0.830 rs11725652 chr4:98878362 G/A cg17366294 chr4:99064904 C4orf37 0.71 7.28 0.55 3.33e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6088580 0.602 rs6059840 chr20:33030405 G/A cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs2288073 0.965 rs6545335 chr2:24422011 G/A cg02683114 chr2:24398427 C2orf84 -0.25 -5.67 -0.45 9.72e-8 Venous thromboembolism (SNP x SNP interaction); TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg03885119 chr10:117885028 GFRA1 -0.86 -6.85 -0.52 3.06e-10 Follicular lymphoma; TGCT cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg10935138 chr17:73851978 WBP2 1.05 9.62 0.65 1.08e-16 Psoriasis; TGCT cis rs826838 0.868 rs12322306 chr12:39130021 A/G cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs2288884 0.767 rs3752119 chr19:52551498 C/T cg15405931 chr19:52693188 PPP2R1A -0.64 -4.5 -0.38 1.51e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs6988636 1.000 rs59601467 chr8:124193488 C/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs1061377 0.501 rs62308278 chr4:39162658 G/T cg20847110 chr4:39482781 LOC401127 0.17 4.86 0.4 3.49e-6 Uric acid levels; TGCT cis rs1008375 1.000 rs6449319 chr4:17640283 T/A cg18681998 chr4:17616180 MED28 1.07 12.28 0.74 3.52e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6693567 0.565 rs834238 chr1:150366469 G/T cg09579323 chr1:150459698 TARS2 0.53 4.71 0.39 6.56e-6 Migraine; TGCT cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs137603 0.602 rs137654 chr22:39732413 C/T cg01093212 chr22:39715156 SNORD43;RPL3 -0.52 -5.09 -0.42 1.29e-6 Primary biliary cholangitis; TGCT cis rs2204008 0.684 rs11514164 chr12:38036494 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.89 0.4 3.05e-6 Bladder cancer; TGCT cis rs11122272 0.735 rs2749717 chr1:231489353 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.6 -0.51 1.09e-9 Hemoglobin concentration; TGCT cis rs6121246 0.865 rs6058421 chr20:30295013 G/C cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs6088580 0.634 rs6088484 chr20:32985961 T/C cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs7833790 0.700 rs28390260 chr8:82769175 A/T cg06027949 chr8:82754900 SNX16 0.67 5.14 0.42 1.06e-6 Diastolic blood pressure; TGCT cis rs2153535 0.580 rs6597337 chr6:8531652 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs75059851 0.756 rs11223651 chr11:133841034 A/G cg14047540 chr11:133829660 NA 0.53 5.47 0.44 2.33e-7 Schizophrenia; TGCT cis rs12615966 0.651 rs72830473 chr2:105411202 C/A cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs9560113 0.959 rs4771756 chr13:112176083 T/G cg14154082 chr13:112174009 NA 0.34 4.65 0.39 8.49e-6 Menarche (age at onset); TGCT cis rs78545713 1.000 rs78661760 chr6:26250033 A/T cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.71 -4.68 -0.39 7.39e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs2456568 0.805 rs55649862 chr11:93682888 G/T cg26875233 chr11:93583750 C11orf90 -0.45 -5.65 -0.45 1.04e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6500602 0.647 rs1659497 chr16:4594635 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.31 -5.9 -0.47 3.25e-8 Schizophrenia; TGCT cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg08280861 chr8:58055591 NA 0.37 5.03 0.41 1.66e-6 Developmental language disorder (linguistic errors); TGCT cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.69 4.91 0.4 2.75e-6 Platelet count; TGCT cis rs2836950 0.545 rs4818001 chr21:40575088 T/C cg06238570 chr21:40685208 BRWD1 -0.62 -6.42 -0.5 2.58e-9 Menarche (age at onset); TGCT cis rs6964587 0.967 rs7781221 chr7:91664645 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs11098499 0.604 rs2389887 chr4:120570644 T/C cg09307838 chr4:120376055 NA 0.64 6.23 0.49 6.81e-9 Corneal astigmatism; TGCT cis rs950027 0.595 rs2486288 chr15:45712339 T/C cg26924012 chr15:45694286 SPATA5L1 0.8 9.1 0.63 1.83e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs6582630 0.555 rs12372536 chr12:38400864 C/G cg13010199 chr12:38710504 ALG10B 0.59 4.68 0.39 7.35e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs78545713 0.881 rs74608402 chr6:26240474 C/T cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.79 -4.45 -0.37 1.87e-5 Iron status biomarkers (total iron binding capacity); TGCT cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9660180 0.836 rs72634845 chr1:1704899 G/A cg17747265 chr1:1875780 NA -0.38 -7.18 -0.54 5.67e-11 Body mass index; TGCT cis rs295140 0.668 rs3769482 chr2:201173100 C/G cg04283868 chr2:201171347 SPATS2L 0.6 5.68 0.45 9.27e-8 QT interval; TGCT cis rs1372520 0.684 rs1442148 chr4:90748846 T/A cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs3780378 0.875 rs4587378 chr9:5002011 C/T cg02405213 chr9:5042618 JAK2 -0.54 -6.42 -0.5 2.57e-9 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs875971 0.895 rs1974769 chr7:65950614 G/A cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg20849893 chr7:64541193 NA 0.49 5.1 0.42 1.24e-6 Calcium levels; TGCT cis rs7677751 0.747 rs1800809 chr4:55093914 A/G cg17187183 chr4:55093834 PDGFRA 0.55 7.06 0.54 1.05e-10 Corneal astigmatism; TGCT cis rs7666738 0.649 rs28865589 chr4:98954279 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.3 0.55 2.96e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs317689 0.581 rs160829 chr12:69769538 G/C cg11871910 chr12:69753446 YEATS4 0.58 5.18 0.42 8.72e-7 Response to diuretic therapy; TGCT cis rs8177253 0.965 rs7638018 chr3:133495461 C/T cg11941060 chr3:133502564 NA 0.29 6.43 0.5 2.51e-9 Iron status biomarkers; TGCT cis rs4665809 0.887 rs28699126 chr2:26357294 C/T cg04944784 chr2:26401820 FAM59B -0.68 -6.09 -0.48 1.28e-8 Gut microbiome composition (summer); TGCT cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9457247 1.000 rs444988 chr6:167389674 A/T cg23791538 chr6:167370224 RNASET2 -0.53 -5.18 -0.42 8.72e-7 Crohn's disease; TGCT cis rs727563 0.635 rs5751141 chr22:42107745 A/G cg03806693 chr22:41940476 POLR3H 1.07 11.53 0.72 2.33e-21 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2153535 0.580 rs1034272 chr6:8469335 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs3960554 0.673 rs112680895 chr7:75623520 G/A cg17325771 chr7:75508891 RHBDD2 -0.59 -4.68 -0.39 7.44e-6 Eotaxin levels; TGCT cis rs4654899 0.758 rs35913932 chr1:21423025 G/T cg01072550 chr1:21505969 NA -0.57 -9.35 -0.64 4.68e-16 Superior frontal gyrus grey matter volume; TGCT cis rs6964587 0.869 rs406 chr7:91546526 C/A cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs11122272 0.614 rs78172021 chr1:231525160 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg10108389 chr3:44770937 ZNF501 -0.47 -4.67 -0.39 7.6e-6 Depressive symptoms; TGCT cis rs7829975 0.514 rs2979139 chr8:8268313 A/G cg08975724 chr8:8085496 FLJ10661 0.59 5.21 0.42 7.78e-7 Mood instability; TGCT cis rs4953076 0.574 rs4953074 chr2:44464629 C/T cg00619915 chr2:44497795 NA -0.23 -5.07 -0.41 1.41e-6 Height; TGCT cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs826838 0.616 rs10880738 chr12:38617762 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs66573146 0.634 rs55633489 chr4:6988745 C/A cg05069807 chr4:6945702 TBC1D14 0.31 4.83 0.4 3.91e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4087296 0.671 rs3859076 chr16:82379801 G/A cg05453434 chr16:83371223 CDH13 0.31 4.44 0.37 1.93e-5 Bone mineral density; TGCT cis rs6500602 0.727 rs2160567 chr16:4535557 C/T cg08645402 chr16:4508243 NA 0.18 4.92 0.4 2.74e-6 Schizophrenia; TGCT cis rs17376456 0.877 rs10044066 chr5:93437580 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs7219021 0.705 rs2270576 chr17:47007963 C/T cg26022315 chr17:47021804 SNF8 -0.54 -4.65 -0.39 8.2e-6 Schizophrenia or bipolar disorder; TGCT cis rs7246657 0.722 rs2972430 chr19:38182111 C/T cg03611452 chr19:38183253 ZNF781 -0.59 -4.69 -0.39 7.15e-6 Coronary artery calcification; TGCT cis rs10832963 0.961 rs10832954 chr11:18643559 G/A cg09201001 chr11:18656081 SPTY2D1 1.03 11.22 0.71 1.32e-20 Breast cancer; TGCT cis rs1670533 0.872 rs11727136 chr4:1051804 G/A cg20887711 chr4:1340912 KIAA1530 0.63 5.03 0.41 1.65e-6 Recombination rate (females); TGCT cis rs1453308 0.507 rs2219062 chr2:237149375 C/T cg19324714 chr2:237145437 ASB18 0.44 4.46 0.37 1.84e-5 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs7208859 0.623 rs9906957 chr17:29157755 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs5769765 0.862 rs9616381 chr22:50312382 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs7726839 0.540 rs28364691 chr5:664084 G/A cg20362242 chr5:692897 TPPP 0.51 4.66 0.39 8.11e-6 Obesity-related traits; TGCT cis rs10992471 0.603 rs11792019 chr9:95195229 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.94 -0.47 2.62e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7681440 0.904 rs7672979 chr4:90767873 A/G cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs3087591 0.960 rs8067021 chr17:29555078 T/A cg24425628 chr17:29625626 OMG;NF1 -0.46 -7.15 -0.54 6.46e-11 Hip circumference; TGCT cis rs6964587 1.000 rs7800582 chr7:91701346 G/A cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs10779751 0.922 rs4845985 chr1:11288618 G/A cg08854313 chr1:11322531 MTOR 0.96 10.11 0.67 6.65e-18 Body mass index; TGCT cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg13695892 chr22:41940480 POLR3H -0.87 -8.01 -0.58 6.94e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs116095464 0.558 rs28729548 chr5:229025 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs6089829 0.962 rs11086151 chr20:61664644 C/T cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs727479 0.523 rs8034835 chr15:51512664 A/G cg19946085 chr15:51559439 CYP19A1 -0.31 -4.48 -0.37 1.7e-5 Estradiol levels; TGCT cis rs7674212 0.570 rs1031804 chr4:104066049 C/T cg16532752 chr4:104119610 CENPE -0.6 -5.47 -0.44 2.34e-7 Type 2 diabetes; TGCT cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg00786635 chr1:25594202 NA 0.58 6.07 0.48 1.43e-8 Erythrocyte sedimentation rate; TGCT cis rs271674 1.000 rs271674 chr17:47978986 A/G cg05310240 chr17:47979069 NA -0.37 -5.99 -0.47 2.07e-8 White matter hyperintensity volume in cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy; TGCT cis rs172166 0.694 rs1770131 chr6:28086413 C/T cg10876282 chr6:28092338 ZSCAN16 0.51 4.69 0.39 6.99e-6 Cardiac Troponin-T levels; TGCT cis rs2153535 0.580 rs9393019 chr6:8462091 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9902453 0.765 rs3115087 chr17:28030267 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 6.84 0.52 3.17e-10 Coffee consumption (cups per day); TGCT cis rs8077577 0.895 rs11871491 chr17:18105656 T/C cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs5750830 0.649 rs4821893 chr22:39797779 G/A cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs1568889 1.000 rs9783281 chr11:28033786 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.87 8.12 0.59 3.93e-13 Bipolar disorder; TGCT cis rs11696501 0.688 rs4812955 chr20:44324638 G/C cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs2204008 0.713 rs12366709 chr12:38210179 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs9653442 0.527 rs13003982 chr2:100759078 T/C cg07810366 chr2:100720526 AFF3 -0.35 -5.03 -0.41 1.69e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs67460515 0.892 rs11718905 chr3:161051793 G/A cg03342759 chr3:160939853 NMD3 -0.48 -5.16 -0.42 9.65e-7 Parkinson's disease; TGCT cis rs1801251 0.896 rs6719061 chr2:233695885 C/T cg08000102 chr2:233561755 GIGYF2 -0.59 -6.22 -0.49 6.86e-9 Coronary artery disease; TGCT cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.664 rs7847141 chr9:5097171 A/T cg02405213 chr9:5042618 JAK2 -0.76 -10.67 -0.69 3.05e-19 Pediatric autoimmune diseases; TGCT cis rs7211079 0.581 rs66994322 chr17:78131240 G/T cg09238746 chr17:78121135 EIF4A3 -0.74 -5.11 -0.42 1.16e-6 Myocardial infarction; TGCT cis rs3809566 0.534 rs4775609 chr15:63332009 A/C cg08198488 chr15:63333792 TPM1 -0.32 -4.63 -0.38 9.22e-6 Platelet count; TGCT cis rs62244186 0.659 rs4431151 chr3:44510906 G/C cg15687855 chr3:44754131 ZNF502 -0.44 -5.11 -0.42 1.18e-6 Depressive symptoms; TGCT cis rs10114408 0.959 rs7852292 chr9:96648085 C/T cg13679303 chr9:96623674 NA -0.36 -4.6 -0.38 1.04e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2445762 1.000 rs2445762 chr15:51617708 T/C cg00184732 chr15:51633821 GLDN 0.41 4.59 0.38 1.08e-5 Hormone measurements; TGCT cis rs7666738 0.791 rs12233867 chr4:98950233 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs868036 0.609 rs2127163 chr15:68090842 C/T cg27219399 chr15:67835830 MAP2K5 0.34 4.49 0.37 1.6e-5 Restless legs syndrome; TGCT cis rs1023500 0.505 rs134889 chr22:42674350 A/T cg15557168 chr22:42548783 NA -0.21 -4.99 -0.41 2.03e-6 Schizophrenia; TGCT cis rs611744 0.905 rs610891 chr8:109161003 C/T cg21045802 chr8:109455806 TTC35 -0.49 -4.5 -0.37 1.53e-5 Dupuytren's disease; TGCT cis rs514406 0.505 rs146750 chr1:53183447 C/G cg08859206 chr1:53392774 SCP2 -0.35 -5.18 -0.42 8.58e-7 Monocyte count; TGCT cis rs71191701 1.000 rs71191701 chr9:139322257 G/C cg13741927 chr9:139327495 INPP5E -0.29 -6.75 -0.52 4.99e-10 Myeloid white cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts;Sum neutrophil eosinophil counts; TGCT cis rs10751667 0.643 rs10751671 chr11:944479 T/G cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs8017423 0.647 rs12882575 chr14:90820454 C/G cg04374321 chr14:90722782 PSMC1 -0.56 -5.62 -0.45 1.19e-7 Mortality in heart failure; TGCT cis rs992157 0.560 rs6738394 chr2:219110625 G/A cg00012203 chr2:219082015 ARPC2 -0.81 -9.21 -0.64 1.03e-15 Colorectal cancer; TGCT cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg13395646 chr4:1353034 KIAA1530 -0.47 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs11696501 0.694 rs2171371 chr20:44273482 T/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg02187348 chr16:89574699 SPG7 0.6 6.26 0.49 5.79e-9 Multiple myeloma (IgH translocation); TGCT cis rs2067615 0.579 rs10746066 chr12:107129108 G/A cg15890332 chr12:107067104 RFX4 0.28 5.55 0.45 1.68e-7 Heart rate; TGCT cis rs1062177 1.000 rs2964584 chr5:151142878 T/C cg00977110 chr5:151150581 G3BP1 0.4 4.55 0.38 1.26e-5 Preschool internalizing problems; TGCT cis rs5750830 0.649 rs5757663 chr22:39821319 T/C cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs12477438 1.000 rs12466388 chr2:99916538 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -6.3 -0.49 4.62e-9 Chronic sinus infection; TGCT cis rs10256972 0.616 rs6957733 chr7:1106327 T/G cg18402987 chr7:1209562 NA 0.39 4.48 0.37 1.68e-5 Longevity;Endometriosis; TGCT cis rs6684514 1.000 rs10752615 chr1:156248609 T/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6665290 0.901 rs61834004 chr1:227202782 G/A cg10327440 chr1:227177885 CDC42BPA -0.99 -20.19 -0.88 5.19e-41 Myeloid white cell count; TGCT cis rs3770081 1.000 rs60479377 chr2:86283948 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs2370759 1.000 rs75984055 chr10:32591276 T/C cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs6570726 0.791 rs6915094 chr6:145883540 C/G cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs116095464 0.558 rs10059907 chr5:205360 G/C cg22857025 chr5:266934 NA -0.34 -6.42 -0.5 2.63e-9 Breast cancer; TGCT cis rs911555 1.000 rs754287 chr14:103997525 T/A cg12935359 chr14:103987150 CKB 0.35 4.96 0.41 2.23e-6 Intelligence (multi-trait analysis); TGCT cis rs2760061 0.583 rs1774757 chr1:228211135 C/G cg18477163 chr1:228402036 OBSCN 0.36 7.28 0.55 3.39e-11 Diastolic blood pressure; TGCT cis rs1218582 0.772 rs2102423 chr1:154916068 A/G cg06221963 chr1:154839813 KCNN3 -0.71 -11.68 -0.72 1.06e-21 Prostate cancer; TGCT cis rs9811920 0.809 rs796976 chr3:99621002 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.46 -5.2 -0.42 7.88e-7 Axial length; TGCT cis rs11098499 0.754 rs12507565 chr4:120251121 G/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs394563 0.591 rs6570964 chr6:149691859 G/A cg16235748 chr6:149772707 ZC3H12D 0.44 5.03 0.41 1.66e-6 Dupuytren's disease; TGCT cis rs6089829 0.855 rs6062781 chr20:61667128 G/A cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.562 rs2955381 chr17:17945500 G/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs6840360 0.615 rs7669761 chr4:152609304 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.15 -0.48 9.82e-9 Intelligence (multi-trait analysis); TGCT cis rs4285028 0.699 rs4676758 chr3:121583415 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.79 6.75 0.52 5.11e-10 Multiple sclerosis; TGCT cis rs9611565 0.694 rs4822032 chr22:41925535 T/C cg06481639 chr22:41940642 POLR3H -0.58 -5.26 -0.43 6.02e-7 Vitiligo; TGCT cis rs425277 1.000 rs262641 chr1:2104981 C/T cg03732007 chr1:2071316 PRKCZ -0.23 -4.85 -0.4 3.56e-6 Height; TGCT cis rs875971 0.830 rs6976714 chr7:65891461 G/A cg11764359 chr7:65958608 NA 0.58 5.32 0.43 4.62e-7 Aortic root size; TGCT cis rs9527 0.590 rs7894959 chr10:104756182 C/T cg15744005 chr10:104629667 AS3MT -0.42 -5.0 -0.41 1.93e-6 Arsenic metabolism; TGCT cis rs9611519 1.000 rs5758268 chr22:41622419 A/T cg03806693 chr22:41940476 POLR3H -0.67 -6.4 -0.5 2.9e-9 Neuroticism; TGCT cis rs9913156 0.748 rs72835619 chr17:4557285 G/A cg23387401 chr17:4582204 PELP1 0.31 4.57 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs655029 0.837 rs632964 chr2:31463866 G/C cg14018959 chr2:31480232 EHD3 -0.36 -4.88 -0.4 3.25e-6 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs514406 0.861 rs7526275 chr1:53245849 C/T cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs9926296 0.607 rs2079672 chr16:89884917 A/G cg27121462 chr16:89883253 FANCA -0.54 -5.07 -0.41 1.41e-6 Vitiligo; TGCT cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.962 rs6089824 chr20:61659207 A/G cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs1059312 0.808 rs10847693 chr12:129292006 G/A cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs1865760 0.865 rs9467652 chr6:25959127 A/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs4819052 0.851 rs2838858 chr21:46681093 T/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.82 7.39 0.55 1.85e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3796352 1.000 rs35849389 chr3:53005235 A/G cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2153535 0.580 rs9406167 chr6:8502852 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 4.92 0.4 2.73e-6 Schizophrenia; TGCT cis rs950027 0.620 rs1153855 chr15:45660758 C/G cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs7727544 0.684 rs272869 chr5:131677997 A/G cg24060327 chr5:131705240 SLC22A5 -0.59 -6.53 -0.51 1.54e-9 Blood metabolite levels; TGCT cis rs45509595 0.822 rs200484 chr6:27775674 A/G cg10876282 chr6:28092338 ZSCAN16 0.76 4.53 0.38 1.38e-5 Breast cancer; TGCT cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs1635 0.655 rs75885713 chr6:28312356 G/A cg15743358 chr6:28303923 ZNF323 -1.3 -4.94 -0.41 2.45e-6 Schizophrenia; TGCT cis rs9811920 0.695 rs1287284 chr3:99516962 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.44 4.98 0.41 2.08e-6 Axial length; TGCT cis rs9611565 0.592 rs8779 chr22:42070276 T/C cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Vitiligo; TGCT cis rs7829975 0.564 rs2921057 chr8:8318667 C/T cg08975724 chr8:8085496 FLJ10661 0.64 6.16 0.48 9.49e-9 Mood instability; TGCT cis rs3796352 1.000 rs11718752 chr3:53130745 T/C cg15956490 chr3:53032818 SFMBT1 0.49 5.58 0.45 1.41e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9611565 0.649 rs738422 chr22:42123399 C/T cg06634786 chr22:41940651 POLR3H 0.82 7.9 0.58 1.3e-12 Vitiligo; TGCT cis rs7027203 0.964 rs6479512 chr9:96556985 G/A cg13679303 chr9:96623674 NA 0.66 9.82 0.66 3.55e-17 DNA methylation (variation); TGCT cis rs2067615 0.579 rs10778509 chr12:107162918 G/A cg15890332 chr12:107067104 RFX4 0.29 5.89 0.47 3.34e-8 Heart rate; TGCT cis rs908922 0.676 rs4845782 chr1:152492225 A/G cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.16e-9 Hair morphology; TGCT cis rs2230307 0.536 rs522696 chr1:100476662 G/A cg24955406 chr1:100503596 HIAT1 0.75 4.88 0.4 3.2e-6 Carotid intima media thickness; TGCT cis rs2688608 0.588 rs10128205 chr10:75469648 C/G cg19442545 chr10:75533431 FUT11 -0.38 -5.91 -0.47 3.03e-8 Inflammatory bowel disease; TGCT cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg13395646 chr4:1353034 KIAA1530 0.4 4.98 0.41 2.1e-6 Obesity-related traits; TGCT cis rs7843479 0.965 rs13269198 chr8:21823025 G/A cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs7714584 1.000 rs10058821 chr5:150226385 A/G cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT trans rs621559 0.535 rs665462 chr1:43672011 T/C cg19324027 chr2:74699582 MRPL53 0.87 6.75 0.52 5.12e-10 Telomere length; TGCT cis rs7666738 0.515 rs13131874 chr4:98779183 A/G cg17366294 chr4:99064904 C4orf37 0.62 5.78 0.46 5.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17711722 0.701 rs4467826 chr7:65368708 A/G cg00343986 chr7:65444356 GUSB 0.26 6.12 0.48 1.15e-8 Calcium levels; TGCT cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg13866156 chr1:1669148 SLC35E2 -0.23 -5.53 -0.44 1.8e-7 Body mass index; TGCT cis rs801193 1.000 rs1553610 chr7:66197233 T/C cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs13256369 0.851 rs13266562 chr8:8564065 T/C cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg18230493 chr5:56204884 C5orf35 -0.84 -6.45 -0.5 2.23e-9 Initial pursuit acceleration; TGCT cis rs7772486 0.846 rs2748499 chr6:146315002 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.55 -0.38 1.28e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6569992 0.500 rs12660713 chr6:135517996 G/A cg22676075 chr6:135203613 NA 0.77 4.86 0.4 3.51e-6 Red blood cell traits; TGCT trans rs6089829 0.962 rs3746749 chr20:61667333 T/C cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs200895692 1 rs200895692 chr1:43421956 CGCCTGTAATCCCAG/C cg00102166 chr1:43425337 SLC2A1 -0.73 -6.36 -0.5 3.58e-9 Monocyte count; TGCT cis rs6969780 0.722 rs4722666 chr7:27197601 C/G cg04321618 chr7:27170880 HOXA4 -0.52 -5.18 -0.42 8.67e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs1532993 0.518 rs11097566 chr4:98587459 C/T cg05340658 chr4:99064831 C4orf37 0.41 4.84 0.4 3.8e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs875971 0.830 rs809025 chr7:65849819 C/G cg11764359 chr7:65958608 NA 0.57 5.28 0.43 5.64e-7 Aortic root size; TGCT trans rs7698623 0.850 rs7678318 chr4:88768888 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT trans rs17685 0.743 rs10277259 chr7:75802674 A/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1348850 0.651 rs1901826 chr2:178225266 G/A cg22681709 chr2:178499509 PDE11A -0.35 -4.51 -0.38 1.5e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs526231 0.578 rs10463553 chr5:102249207 T/C cg23492399 chr5:102201601 PAM -0.51 -4.49 -0.37 1.62e-5 Primary biliary cholangitis; TGCT cis rs614226 0.872 rs787827 chr12:120937794 A/G cg10072921 chr12:121022843 NA -0.45 -4.76 -0.39 5.27e-6 Type 1 diabetes nephropathy; TGCT cis rs2228479 0.850 rs62054610 chr16:89816920 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs2180341 0.814 rs6569488 chr6:127726256 C/T cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs9549260 0.755 rs7324319 chr13:41233505 G/C cg21288729 chr13:41239152 FOXO1 0.98 10.14 0.67 5.74e-18 Red blood cell count; TGCT cis rs12681288 0.782 rs2600497 chr8:1026220 A/G cg04851639 chr8:1020857 NA -0.33 -5.71 -0.46 7.82e-8 Schizophrenia; TGCT cis rs3091242 0.933 rs7541095 chr1:25761291 T/C cg00786635 chr1:25594202 NA 0.54 5.7 0.46 8.3e-8 Erythrocyte sedimentation rate; TGCT cis rs9467773 1.000 rs6456733 chr6:26566804 C/T cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs4891159 0.790 rs9950025 chr18:74113596 C/G cg24786174 chr18:74118243 ZNF516 0.63 9.98 0.67 1.38e-17 Longevity; TGCT cis rs11098499 0.865 rs28753180 chr4:120405367 A/T cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs2228479 0.717 rs9282682 chr16:89805794 A/G cg26513180 chr16:89883248 FANCA 0.78 4.56 0.38 1.23e-5 Skin colour saturation; TGCT cis rs7336332 0.628 rs9581855 chr13:28018014 G/A cg22138327 chr13:27999177 GTF3A 0.83 6.64 0.51 9e-10 Weight; TGCT cis rs832540 0.864 rs832576 chr5:56163255 C/A cg24531977 chr5:56204891 C5orf35 -0.51 -5.21 -0.42 7.61e-7 Coronary artery disease; TGCT cis rs10833905 0.680 rs10833894 chr11:23027476 A/G cg06387204 chr11:22647648 FANCF -0.52 -4.69 -0.39 7.07e-6 Sudden cardiac arrest; TGCT cis rs12530845 1.000 rs12540325 chr7:135334111 T/C cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs950169 0.840 rs62029595 chr15:84955301 C/T cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs10197940 0.578 rs6718653 chr2:152346118 C/A cg19508488 chr2:152266495 RIF1 0.59 4.98 0.41 2.11e-6 Lung cancer; TGCT cis rs7772486 0.681 rs9390343 chr6:146010527 A/T cg05347473 chr6:146136440 FBXO30 -0.49 -4.67 -0.39 7.63e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs17539620 0.624 rs62432735 chr6:154834055 T/C cg20019720 chr6:154832845 CNKSR3 0.56 4.75 0.39 5.5e-6 Lipoprotein (a) levels; TGCT cis rs28493229 0.708 rs73546845 chr19:41158717 C/T cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs2841277 0.708 rs10083490 chr14:105402418 A/G cg21017887 chr14:105400489 NA -0.38 -5.42 -0.44 3.03e-7 Rheumatoid arthritis; TGCT cis rs7246657 0.943 rs10405407 chr19:37839164 C/T cg03233940 chr19:37894644 NA -0.34 -4.49 -0.37 1.59e-5 Coronary artery calcification; TGCT cis rs806215 1.000 rs806196 chr7:127248414 A/G cg25922125 chr7:127225783 GCC1 0.59 5.98 0.47 2.21e-8 Type 2 diabetes; TGCT cis rs732765 0.734 rs10133860 chr14:75186425 G/A cg06637938 chr14:75390232 RPS6KL1 -0.55 -4.48 -0.37 1.71e-5 Non-small cell lung cancer; TGCT cis rs7829975 0.533 rs35900578 chr8:8719513 G/A cg06636001 chr8:8085503 FLJ10661 0.77 6.9 0.53 2.4e-10 Mood instability; TGCT cis rs11264213 0.901 rs645123 chr1:36458075 T/C cg27506609 chr1:36549197 TEKT2 0.39 4.64 0.38 8.67e-6 Schizophrenia; TGCT cis rs71435601 0.657 rs490757 chr2:21388224 C/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs6988636 0.534 rs62521770 chr8:124104070 G/A cg27053337 chr8:124217698 FAM83A 0.56 4.82 0.4 4.1e-6 Urinary uromodulin levels; TGCT cis rs7267979 1.000 rs2257496 chr20:25279315 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28595532 0.920 rs114678295 chr4:119756281 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT trans rs7618501 0.574 rs6765484 chr3:50041313 C/T cg21659725 chr3:3221576 CRBN -0.75 -8.83 -0.62 8.16e-15 Intelligence (multi-trait analysis); TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg24675658 chr1:53192096 ZYG11B -0.84 -10.27 -0.68 2.8e-18 Monocyte count; TGCT cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg16423285 chr20:60520624 NA -0.63 -7.09 -0.54 8.93e-11 Body mass index; TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.52 4.48 0.37 1.69e-5 Prudent dietary pattern; TGCT cis rs11264213 0.901 rs688833 chr1:36455600 C/T cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs3733585 0.637 rs6850684 chr4:9964380 G/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.58 -0.51 1.2e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11098499 0.954 rs59866101 chr4:120296591 T/G cg09307838 chr4:120376055 NA 0.66 6.48 0.5 1.98e-9 Corneal astigmatism; TGCT cis rs7666738 0.830 rs10440379 chr4:98902822 G/T cg05340658 chr4:99064831 C4orf37 0.51 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs68170813 0.559 rs76145119 chr7:107052368 C/T cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs1008375 1.000 rs10939742 chr4:17659936 G/T cg18681998 chr4:17616180 MED28 1.01 11.93 0.73 2.52e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7178572 1.000 rs2055901 chr15:77759295 G/A cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs4285028 0.796 rs12638492 chr3:121711763 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.75 -6.28 -0.49 5.3300000000000004e-09 Multiple sclerosis; TGCT cis rs12541335 0.639 rs68063696 chr8:22153236 A/G cg02463440 chr8:22132932 PIWIL2 0.25 4.85 0.4 3.6e-6 Hypertriglyceridemia; TGCT cis rs6540559 0.611 rs61747285 chr1:210004332 G/A cg21951975 chr1:209979733 IRF6 0.64 4.82 0.4 4.12e-6 Cleft lip with or without cleft palate; TGCT cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6815814 0.861 rs10004195 chr4:38784724 T/A cg02016764 chr4:38805732 TLR1 -0.28 -4.52 -0.38 1.41e-5 Breast cancer; TGCT cis rs7605378 1.000 rs7605378 chr2:200676926 A/C cg17644776 chr2:200775616 C2orf69 0.26 5.1 0.42 1.25e-6 Osteoporosis; TGCT cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs6921919 0.609 rs67211468 chr6:28391987 T/C cg18815343 chr6:28367644 ZSCAN12 -0.53 -5.16 -0.42 9.45e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10791097 0.720 rs7119425 chr11:130733185 C/T cg14779329 chr11:130786720 SNX19 0.28 4.81 0.4 4.27e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1799949 0.965 rs2236762 chr17:41226675 A/T cg10047753 chr17:41438598 NA 0.79 7.48 0.56 1.19e-11 Menopause (age at onset); TGCT cis rs10791097 0.677 rs11222359 chr11:130730648 A/G cg05962950 chr11:130786565 SNX19 0.82 9.91 0.66 2.06e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg13866156 chr1:1669148 SLC35E2 -0.21 -5.01 -0.41 1.81e-6 Body mass index; TGCT cis rs7659604 0.676 rs4516739 chr4:122699741 G/T cg20573242 chr4:122745356 CCNA2 0.51 4.69 0.39 7.21e-6 Type 2 diabetes; TGCT cis rs7179456 0.544 rs2555357 chr15:59087115 A/G cg05156742 chr15:59063176 FAM63B 0.56 5.26 0.43 6.22e-7 Asperger disorder; TGCT cis rs7655841 0.704 rs7671508 chr4:129977667 G/T cg26347359 chr4:129759716 PHF17 -0.43 -4.98 -0.41 2.07e-6 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs2492301 0.506 rs11264049 chr1:37902135 A/G cg17933807 chr1:38061675 GNL2 -0.56 -5.57 -0.45 1.52e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs16854884 0.837 rs4380409 chr3:143800896 A/G cg06585982 chr3:143692056 C3orf58 0.61 4.72 0.39 6.19e-6 Economic and political preferences (feminism/equality); TGCT cis rs4886920 0.563 rs55726435 chr15:78071083 C/T cg03457338 chr15:78040120 NA 0.19 4.76 0.39 5.22e-6 Neuroticism; TGCT cis rs6089829 0.962 rs4586690 chr20:61658595 G/T cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs533581 0.866 rs2968474 chr16:88970566 A/G cg16701003 chr16:89028210 CBFA2T3 -0.39 -5.1 -0.42 1.25e-6 Social autistic-like traits; TGCT cis rs35146811 0.660 rs3779045 chr7:99779259 T/C cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT trans rs7618501 1.000 rs2271961 chr3:49878113 C/T cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.741 rs4339857 chr1:154888962 A/G cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg08736216 chr1:53307985 ZYG11A -0.25 -4.83 -0.4 4.01e-6 Monocyte count; TGCT cis rs56399783 0.901 rs73051415 chr7:2850643 C/T cg19731401 chr7:2775893 GNA12 0.37 4.97 0.41 2.14e-6 Childhood ear infection; TGCT cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.94 -0.41 2.52e-6 Bipolar disorder; TGCT cis rs7043114 0.525 rs2516567 chr9:95187418 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.59 -0.45 1.36e-7 Height; TGCT cis rs9394841 0.692 rs9357371 chr6:41885319 A/C cg08135965 chr6:41755394 TOMM6 0.57 5.11 0.42 1.21e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs11098499 0.818 rs12498599 chr4:120468503 C/T cg09307838 chr4:120376055 NA 0.72 6.87 0.52 2.81e-10 Corneal astigmatism; TGCT cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg05985448 chr10:134359359 INPP5A 0.22 5.1 0.42 1.26e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs642803 0.591 rs620088 chr11:65508986 G/A cg27068330 chr11:65405492 SIPA1 0.64 5.68 0.45 8.87e-8 Urate levels; TGCT cis rs8031584 0.663 rs1917421 chr15:31187663 C/T cg08704250 chr15:31115839 NA -0.42 -6.28 -0.49 5.27e-9 Huntington's disease progression; TGCT cis rs4654899 0.802 rs12401413 chr1:21236503 T/C cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs2997447 0.761 rs17257093 chr1:26436231 C/A cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg13409248 chr3:40428643 ENTPD3 0.57 4.6 0.38 1.03e-5 Renal cell carcinoma; TGCT trans rs561341 0.882 rs2521594 chr17:30302087 C/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs7804356 0.954 rs10225924 chr7:26839954 C/T cg03456212 chr7:26904342 SKAP2 -0.61 -4.7 -0.39 6.82e-6 Type 1 diabetes; TGCT cis rs12681288 0.676 rs34435811 chr8:990630 T/A cg04851639 chr8:1020857 NA -0.29 -4.68 -0.39 7.51e-6 Schizophrenia; TGCT cis rs858239 0.570 rs10271613 chr7:23162586 G/A cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg20607798 chr8:58055168 NA 0.67 5.62 0.45 1.22e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs11942114 chr4:99066261 C/G cg05340658 chr4:99064831 C4orf37 0.52 5.92 0.47 2.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.966 rs2261784 chr20:25262396 G/C cg14121845 chr20:25566513 NINL 0.51 5.5 0.44 2.04e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg10108389 chr3:44770937 ZNF501 -0.48 -4.94 -0.41 2.48e-6 Depressive symptoms; TGCT cis rs7772486 0.776 rs2265467 chr6:146218339 T/A cg23711669 chr6:146136114 FBXO30 0.83 9.16 0.64 1.32e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs9372498 0.536 rs1319988 chr6:118782379 G/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs10089 1.000 rs72794401 chr5:127517626 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.82 7.66 0.57 4.61e-12 Ileal carcinoids; TGCT cis rs9787249 0.957 rs11206754 chr1:40216234 A/G cg24920358 chr1:40204285 PPIE 0.58 10.58 0.69 4.85e-19 Blood protein levels; TGCT cis rs12477438 0.520 rs6542866 chr2:99764592 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs7542091 0.704 rs7550330 chr1:210044587 G/A cg23283495 chr1:209979779 IRF6 0.55 5.47 0.44 2.34e-7 Monobrow; TGCT cis rs6121246 0.609 rs6087783 chr20:30421224 T/G cg18721089 chr20:30220636 NA -0.37 -4.46 -0.37 1.79e-5 Mean corpuscular hemoglobin; TGCT cis rs1891275 0.509 rs76313529 chr10:93443076 T/C cg07889827 chr10:93443413 NA -0.33 -6.88 -0.53 2.59e-10 Intelligence (multi-trait analysis); TGCT cis rs6032067 0.673 rs13042474 chr20:43893068 G/T cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -6.37 -0.5 3.36e-9 Blood protein levels; TGCT cis rs1472147 0.518 rs1565629 chr7:128445370 G/A cg00260937 chr7:128520193 KCP 0.46 5.12 0.42 1.15e-6 Calcium levels; TGCT cis rs4665809 1.000 rs2891490 chr2:26325927 T/C cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs6074578 0.679 rs1434789 chr20:137900 T/G cg16931068 chr20:139680 DEFB127 0.28 4.82 0.4 4.11e-6 Hirschsprung disease; TGCT cis rs2836950 0.501 rs2836984 chr21:40700949 A/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.48 -0.37 1.7e-5 Menarche (age at onset); TGCT cis rs11203032 0.710 rs10887923 chr10:90930404 C/T cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs7552167 0.925 rs11249020 chr1:24512804 A/G cg01960748 chr1:24522592 NA -0.49 -5.49 -0.44 2.13e-7 Psoriasis vulgaris; TGCT cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg17054783 chr10:134559939 INPP5A 0.26 4.91 0.4 2.78e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2228479 0.850 rs2283565 chr16:89827556 G/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs3733585 0.673 rs4580649 chr4:9948461 G/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.37 -0.5 3.33e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9467773 1.000 rs9467774 chr6:26505036 C/A cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT cis rs3213545 0.700 rs2260399 chr12:121469653 C/T cg02403541 chr12:121454288 C12orf43 0.71 8.0 0.58 7.62e-13 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs981844 0.775 rs17299246 chr4:154743504 C/T cg14289246 chr4:154710475 SFRP2 0.88 6.17 0.48 9.07e-9 Response to statins (LDL cholesterol change); TGCT cis rs3820928 1.000 rs4675119 chr2:227774635 A/C cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs3008870 0.727 rs4582760 chr1:67464394 G/A cg02640540 chr1:67518911 SLC35D1 -0.49 -4.44 -0.37 1.94e-5 Lymphocyte percentage of white cells; TGCT cis rs950027 0.595 rs2486288 chr15:45712339 T/C cg14582100 chr15:45693742 SPATA5L1 0.43 5.38 0.44 3.52e-7 Response to fenofibrate (adiponectin levels); TGCT cis rs9611565 0.649 rs139553 chr22:42187199 A/G cg13695892 chr22:41940480 POLR3H 0.86 8.19 0.59 2.67e-13 Vitiligo; TGCT cis rs11671005 0.735 rs11881000 chr19:58932788 C/T cg13877915 chr19:58951672 ZNF132 0.65 5.14 0.42 1.04e-6 Mean platelet volume; TGCT cis rs7547997 0.685 rs11264963 chr1:158335533 A/G cg07950803 chr1:158223934 CD1A 0.32 4.98 0.41 2.04e-6 QRS duration; TGCT cis rs7927771 0.832 rs10838698 chr11:47385923 G/A cg21462715 chr11:47870315 NUP160 -0.56 -4.52 -0.38 1.4e-5 Subjective well-being; TGCT trans rs561341 0.700 rs886223 chr17:30229877 G/T cg20587970 chr11:113659929 NA -0.6 -9.12 -0.63 1.65e-15 Hip circumference adjusted for BMI; TGCT cis rs10791323 0.604 rs2257010 chr11:133712348 G/A cg15485101 chr11:133734466 NA 0.42 5.45 0.44 2.62e-7 Childhood ear infection; TGCT cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg23283495 chr1:209979779 IRF6 0.67 5.7 0.46 8.12e-8 Cleft lip with or without cleft palate; TGCT cis rs10170846 0.924 rs3768973 chr2:223436402 C/T cg25565276 chr2:223520875 FARSB 0.75 5.73 0.46 7.09e-8 Schizophrenia (inflammation and infection response interaction); TGCT cis rs3862260 0.509 rs1045827 chr1:120162442 C/T cg11530693 chr1:120165357 ZNF697 -0.2 -4.48 -0.37 1.67e-5 Systemic lupus erythematosus; TGCT cis rs36051895 0.664 rs10115518 chr9:5094559 T/C cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT trans rs114540395 0.858 rs116357148 chr10:103352082 T/A cg10198749 chr1:39920707 MACF1 0.55 7.03 0.53 1.2e-10 Schizophrenia; TGCT cis rs11190604 1.000 rs10883508 chr10:102294413 G/A cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.76e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1887596 0.554 rs547756 chr13:27114904 G/C cg01312412 chr13:27282625 NA -0.28 -4.96 -0.41 2.26e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs7829975 0.711 rs4481596 chr8:8704330 G/C cg06636001 chr8:8085503 FLJ10661 0.75 6.95 0.53 1.82e-10 Mood instability; TGCT cis rs6089829 0.962 rs57684920 chr20:61662639 G/A cg03213289 chr20:61660250 NA -0.63 -8.36 -0.6 1.06e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs10056811 0.556 rs55810502 chr5:74380959 A/G cg00601450 chr5:74908170 NA 0.42 4.44 0.37 1.97e-5 Coronary artery disease; TGCT cis rs763121 0.814 rs5757212 chr22:39053757 G/C cg06022373 chr22:39101656 GTPBP1 0.8 8.25 0.6 1.95e-13 Menopause (age at onset); TGCT cis rs13177918 0.677 rs13177970 chr5:149826010 A/G cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT trans rs459571 0.839 rs10993895 chr9:136887726 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 0.72 7.87 0.58 1.48e-12 Platelet distribution width; TGCT cis rs12681287 0.640 rs4961193 chr8:87486168 C/T cg27223183 chr8:87520930 FAM82B 0.87 6.33 0.49 4.05e-9 Caudate activity during reward; TGCT cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg11494091 chr17:61959527 GH2 0.43 7.51 0.56 9.88e-12 Height; TGCT cis rs2688608 0.592 rs11000760 chr10:75493734 G/A cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs7829975 0.623 rs7010753 chr8:8373956 A/G cg06636001 chr8:8085503 FLJ10661 0.81 7.9 0.58 1.27e-12 Mood instability; TGCT cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs17401966 0.558 rs17402762 chr1:10414470 T/C cg19773385 chr1:10388646 KIF1B -0.22 -5.27 -0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg07636037 chr3:49044803 WDR6 0.88 9.28 0.64 6.89e-16 Menarche (age at onset); TGCT cis rs908922 0.676 rs6658925 chr1:152482801 C/T cg20991723 chr1:152506922 NA -0.49 -6.89 -0.53 2.43e-10 Hair morphology; TGCT cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg12310025 chr6:25882481 NA 0.5 5.17 0.42 8.96e-7 Blood metabolite levels; TGCT cis rs7010267 0.902 rs7006553 chr8:119970779 C/T cg17171407 chr8:119960777 TNFRSF11B 0.33 6.26 0.49 5.67e-9 Total body bone mineral density (age 45-60); TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg25767906 chr1:53392781 SCP2 -0.55 -6.58 -0.51 1.21e-9 Monocyte count; TGCT cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg03188948 chr7:1209495 NA 0.71 6.3 0.49 4.79e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6882046 0.513 rs625970 chr5:88042296 A/G cg22951263 chr5:87985283 NA -0.57 -6.02 -0.48 1.79e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs67311347 1.000 rs11706148 chr3:40407243 A/C cg17264618 chr3:40429014 ENTPD3 0.33 4.73 0.39 6.1e-6 Renal cell carcinoma; TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg19723775 chr5:179050963 HNRNPH1 0.48 4.57 0.38 1.16e-5 Lung cancer; TGCT cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs5769707 0.605 rs6009791 chr22:50025265 T/C cg06623630 chr22:50017776 C22orf34 -0.27 -4.7 -0.39 6.81e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs8078723 0.763 rs4433838 chr17:38143532 C/T cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.69e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs4332037 0.539 rs4470910 chr7:2071723 C/T cg25834613 chr7:1915315 MAD1L1 -0.53 -5.2 -0.42 7.98e-7 Bipolar disorder; TGCT cis rs6840360 0.615 rs66852535 chr4:152472227 C/A cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs3540 0.618 rs2301832 chr15:91040725 A/T cg22089800 chr15:90895588 ZNF774 -0.75 -7.58 -0.56 7.16e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs4665809 0.525 rs10865402 chr2:26535383 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.85 -5.86 -0.47 3.97e-8 Gut microbiome composition (summer); TGCT cis rs7917772 0.636 rs7079231 chr10:104527341 A/G cg05855489 chr10:104503620 C10orf26 -0.63 -5.04 -0.41 1.59e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs478304 0.651 rs4930319 chr11:65555458 G/C cg17480646 chr11:65405466 SIPA1 -0.55 -6.49 -0.5 1.88e-9 Acne (severe); TGCT cis rs12477438 0.798 rs10202452 chr2:99569409 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.87 -8.69 -0.62 1.75e-14 Chronic sinus infection; TGCT cis rs11030122 0.702 rs7950153 chr11:3951337 T/C cg18678763 chr11:4115507 RRM1 -0.48 -5.99 -0.47 2.15e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs10782582 0.609 rs1628063 chr1:76391646 A/G cg10523679 chr1:76189770 ACADM -0.52 -4.73 -0.39 5.94e-6 Daytime sleep phenotypes; TGCT cis rs926938 0.527 rs360679 chr1:115494121 G/T cg12756093 chr1:115239321 AMPD1 0.34 4.96 0.41 2.28e-6 Autism; TGCT cis rs35306767 0.761 rs11253559 chr10:1044809 T/C cg20503657 chr10:835505 NA 0.61 6.71 0.52 6.11e-10 Eosinophil percentage of granulocytes; TGCT cis rs1008375 0.863 rs4590022 chr4:17614434 T/C cg16339924 chr4:17578868 LAP3 0.74 5.88 0.47 3.64e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9534288 0.956 rs2094244 chr13:46605803 T/C cg15192986 chr13:46630673 CPB2 -0.51 -6.62 -0.51 9.95e-10 Blood protein levels; TGCT cis rs7208859 0.623 rs55811708 chr17:29104731 G/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6840360 1.000 rs4696104 chr4:152600451 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.66 -0.45 9.86e-8 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.614 rs2007993 chr17:56590643 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs11676348 0.818 rs7426289 chr2:218966315 C/T cg00012203 chr2:219082015 ARPC2 -0.52 -4.82 -0.4 4.13e-6 Ulcerative colitis; TGCT cis rs9739682 0.636 rs1920101 chr12:62522638 G/A cg10589851 chr12:62653931 USP15 -0.59 -4.49 -0.37 1.62e-5 Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs35000415 0.688 rs34350562 chr7:128718708 A/G cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs9926296 0.568 rs417323 chr16:89746277 T/G cg27121462 chr16:89883253 FANCA -0.56 -5.18 -0.42 8.56e-7 Vitiligo; TGCT cis rs7584330 0.518 rs74003104 chr2:238446823 C/T cg14458575 chr2:238380390 NA 0.43 4.51 0.38 1.48e-5 Prostate cancer; TGCT cis rs10089 0.953 rs4836359 chr5:127385518 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs7246657 0.722 rs16958863 chr19:38124235 A/G cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.7e-6 Coronary artery calcification; TGCT cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg07424592 chr7:64974309 NA -1.28 -7.3 -0.55 2.98e-11 Diabetic kidney disease; TGCT cis rs2180341 1.000 rs2144743 chr6:127633810 A/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs7568458 0.905 rs10172544 chr2:85788270 C/A cg17127132 chr2:85788382 GGCX 0.68 6.1 0.48 1.27e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9549367 0.713 rs2480949 chr13:113853149 T/C cg00898013 chr13:113819073 PROZ 0.53 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs11785400 0.793 rs13248524 chr8:143739343 T/C cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs7267979 1.000 rs2258719 chr20:25275843 C/T cg16686733 chr20:25566563 NINL 0.6 5.97 0.47 2.29e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7824557 0.679 rs4840554 chr8:11134105 T/C cg21775007 chr8:11205619 TDH -0.56 -5.13 -0.42 1.07e-6 Retinal vascular caliber; TGCT trans rs9951602 0.512 rs12607938 chr18:76651887 A/C cg02800362 chr5:177631904 HNRNPAB 1.12 12.75 0.75 2.64e-24 Obesity-related traits; TGCT cis rs2637266 1.000 rs7900616 chr10:78367075 C/T cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs457287 0.772 rs438405 chr9:4824607 G/T cg21184111 chr9:4792285 RCL1 0.48 4.8 0.4 4.55e-6 Platelet count; TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs10256972 0.591 rs11766651 chr7:1161646 A/G cg07092213 chr7:1199455 ZFAND2A -0.46 -4.98 -0.41 2.1e-6 Longevity;Endometriosis; TGCT cis rs8077577 0.943 rs62073603 chr17:18064316 C/T cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs3733606 0.775 rs66514314 chr4:6827238 C/T cg26167625 chr4:7770639 AFAP1;LOC84740 0.37 5.25 0.43 6.5e-7 Platelet count; TGCT cis rs10488029 0.646 rs34699952 chr7:37045543 G/A cg06458904 chr7:36312573 EEPD1 0.39 4.48 0.37 1.64e-5 IgG glycosylation; TGCT cis rs2816062 0.760 rs2745319 chr1:18895078 G/A cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg02073558 chr3:44770973 ZNF501 0.57 5.5 0.44 2.05e-7 Depressive symptoms; TGCT cis rs6725041 0.819 rs10048796 chr2:213083326 C/G cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT cis rs6460942 0.915 rs10267801 chr7:12451931 G/A cg06484146 chr7:12443880 VWDE -0.59 -5.88 -0.47 3.51e-8 Coronary artery disease; TGCT cis rs7178572 0.849 rs1005752 chr15:77818128 C/A cg22256960 chr15:77711686 NA -0.97 -11.03 -0.7 3.83e-20 Type 2 diabetes; TGCT cis rs910187 0.678 rs6122562 chr20:45813847 A/G cg27589058 chr20:45804311 EYA2 -0.34 -7.21 -0.54 4.78e-11 Migraine; TGCT cis rs10875595 0.775 rs66998469 chr5:140659960 T/C cg20560182 chr5:140700478 TAF7 -0.66 -5.06 -0.41 1.49e-6 Pulmonary function decline; TGCT cis rs1401999 1.000 rs6443926 chr3:183706630 A/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs6901004 0.803 rs4947107 chr6:111442505 C/T cg15721981 chr6:111408429 SLC16A10 -0.51 -4.49 -0.37 1.6e-5 Blood metabolite levels; TGCT cis rs9302065 1.000 rs7490267 chr13:95970258 T/C cg26751094 chr13:95954534 ABCC4 -0.32 -5.27 -0.43 5.79e-7 Blood metabolite levels; TGCT cis rs2562456 0.792 rs2562398 chr19:21722949 A/G cg01304269 chr19:21688519 ZNF429 -0.57 -4.77 -0.39 5.02e-6 Pain; TGCT cis rs35883536 0.647 rs10875315 chr1:101044062 G/A cg06223162 chr1:101003688 GPR88 -0.41 -7.55 -0.56 7.99e-12 Monocyte count; TGCT cis rs2836974 0.899 rs34433511 chr21:40618883 A/C cg17971929 chr21:40555470 PSMG1 0.98 9.65 0.65 9.11e-17 Cognitive function; TGCT cis rs10791323 0.569 rs1944734 chr11:133720077 G/A cg03690763 chr11:133734501 NA -0.32 -4.76 -0.39 5.35e-6 Childhood ear infection; TGCT cis rs2072499 0.966 rs6427304 chr1:156156789 A/G cg06970220 chr1:156163860 SLC25A44 0.6 5.1 0.42 1.22e-6 Testicular germ cell tumor; TGCT cis rs9913156 0.793 rs55677157 chr17:4576620 C/T cg19197139 chr17:4613644 ARRB2 0.9 7.7 0.57 3.76e-12 Lymphocyte counts; TGCT cis rs4499344 0.881 rs35447302 chr19:33068499 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.7 -6.08 -0.48 1.4e-8 Mean platelet volume; TGCT cis rs79149102 0.579 rs12593542 chr15:75282147 C/G cg09165964 chr15:75287851 SCAMP5 -1.08 -6.26 -0.49 5.66e-9 Lung cancer; TGCT cis rs9611565 0.571 rs2050032 chr22:42152429 C/T cg13695892 chr22:41940480 POLR3H 0.81 7.4 0.55 1.77e-11 Vitiligo; TGCT cis rs617791 0.508 rs10896074 chr11:65776304 C/T cg09783858 chr11:65769428 EIF1AD;BANF1 0.49 4.49 0.37 1.64e-5 Breast cancer; TGCT trans rs829418 0.582 rs747662 chr1:21947218 C/G cg26917367 chr19:57352807 PEG3;ZIM2;MIMT1 -0.87 -6.68 -0.51 7.11e-10 Neurocognitive impairment in HIV-1 infection (continuous); TGCT cis rs4148883 0.629 rs2602899 chr4:100010128 C/T cg13256891 chr4:100009986 ADH5 0.42 4.49 0.37 1.64e-5 Alcohol dependence; TGCT cis rs2404602 0.647 rs11631394 chr15:76973209 G/T cg23625390 chr15:77176239 SCAPER -0.37 -4.73 -0.39 5.88e-6 Blood metabolite levels; TGCT cis rs16866061 1.000 rs72974205 chr2:225408468 C/T cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs11731606 0.508 rs28497379 chr4:95283789 G/T cg00507259 chr4:95128692 SMARCAD1 0.66 4.93 0.41 2.55e-6 Mean platelet volume; TGCT cis rs10875595 0.779 rs4912746 chr5:140673969 T/C cg20560182 chr5:140700478 TAF7 -0.64 -4.91 -0.4 2.76e-6 Pulmonary function decline; TGCT cis rs6484504 0.576 rs2065208 chr11:31239457 C/T cg14844989 chr11:31128820 NA -0.24 -4.58 -0.38 1.13e-5 Red blood cell count; TGCT cis rs7599312 0.553 rs6710653 chr2:213404893 A/G cg16329650 chr2:213403929 ERBB4 1.06 16.47 0.83 5.13e-33 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs56309584 0.673 rs7219471 chr17:8121594 G/T cg08322244 chr17:8066669 VAMP2 -0.56 -5.2 -0.42 7.95e-7 Initial pursuit acceleration; TGCT trans rs561341 1.000 rs757009 chr17:30243937 A/G cg20587970 chr11:113659929 NA -0.93 -11.69 -0.72 9.7e-22 Hip circumference adjusted for BMI; TGCT cis rs7614311 0.636 rs56165216 chr3:63916620 C/T cg22134162 chr3:63841271 THOC7 -0.42 -5.58 -0.45 1.44e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs7226408 0.857 rs72887014 chr18:34463771 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7752195 0.558 rs77914161 chr6:25233485 T/C cg16898833 chr6:26189333 HIST1H4D 1.27 5.88 0.47 3.55e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg09060608 chr5:178986726 RUFY1 0.53 5.87 0.47 3.66e-8 Lung cancer; TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs9486719 0.843 rs3860229 chr6:97036559 T/C cg06623918 chr6:96969491 KIAA0776 -1.04 -10.25 -0.68 3.11e-18 Migraine;Coronary artery disease; TGCT cis rs6484504 0.532 rs11031330 chr11:31275073 G/A cg14844989 chr11:31128820 NA -0.25 -4.84 -0.4 3.76e-6 Red blood cell count; TGCT cis rs7666738 0.830 rs2903154 chr4:99048151 A/G cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7599312 0.534 rs7355673 chr2:213404389 T/C cg16329650 chr2:213403929 ERBB4 1.06 16.47 0.83 5.13e-33 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs950169 0.845 rs4106951 chr15:84833394 C/G cg11189052 chr15:85197271 WDR73 0.81 6.5 0.5 1.78e-9 Schizophrenia; TGCT cis rs2239547 0.657 rs4687554 chr3:52864135 T/C cg10802521 chr3:52805072 NEK4 -0.63 -5.95 -0.47 2.6e-8 Schizophrenia; TGCT cis rs2404602 0.716 rs67418609 chr15:76627089 C/A cg22467129 chr15:76604101 ETFA -0.6 -7.44 -0.56 1.45e-11 Blood metabolite levels; TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs939658 0.805 rs35832166 chr15:79417994 G/T cg17916960 chr15:79447300 NA -0.5 -7.7 -0.57 3.74e-12 Refractive error; TGCT cis rs2012796 0.785 rs61986597 chr14:81853107 T/C cg02996355 chr14:81879375 NA 0.54 5.35 0.43 4.07e-7 Night sleep phenotypes; TGCT cis rs9486715 0.867 rs9373833 chr6:96904998 A/G cg06623918 chr6:96969491 KIAA0776 -1.1 -16.66 -0.83 1.99e-33 Headache; TGCT cis rs9926296 0.643 rs12596429 chr16:89841374 T/C cg27121462 chr16:89883253 FANCA 0.57 5.32 0.43 4.76e-7 Vitiligo; TGCT cis rs7726839 0.794 rs6883536 chr5:599274 G/A cg09021430 chr5:549028 NA -0.42 -6.04 -0.48 1.66e-8 Obesity-related traits; TGCT cis rs12497850 0.866 rs6791234 chr3:48996137 A/G cg07636037 chr3:49044803 WDR6 0.96 10.52 0.69 6.9e-19 Parkinson's disease; TGCT cis rs910187 0.901 rs6124969 chr20:45816277 C/T cg27589058 chr20:45804311 EYA2 -0.34 -6.27 -0.49 5.61e-9 Migraine; TGCT cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg17554472 chr22:41940697 POLR3H -0.42 -4.58 -0.38 1.13e-5 Vitiligo; TGCT cis rs2549003 0.966 rs2706385 chr5:131831766 T/G cg00255919 chr5:131827918 IRF1 -0.21 -4.9 -0.4 2.89e-6 Asthma (sex interaction); TGCT cis rs6663390 0.510 rs2267896 chr1:208080972 C/T cg03990033 chr1:208084030 CD34 -0.73 -6.41 -0.5 2.77e-9 Facial morphology (factor 18); TGCT cis rs9650657 0.740 rs11250077 chr8:10656437 T/C cg27411982 chr8:10470053 RP1L1 -0.24 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs66573146 0.831 rs1048009 chr4:6988677 G/A cg00086871 chr4:6988644 TBC1D14 0.95 4.78 0.39 4.89e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6722750 0.933 rs4671554 chr2:64411122 T/A cg22352474 chr2:64371530 PELI1 -0.58 -5.16 -0.42 9.64e-7 Neuroticism; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.03 13.57 0.77 2.91e-26 Prudent dietary pattern; TGCT cis rs6831352 1.000 rs6532798 chr4:100054827 C/T cg12011299 chr4:100065546 ADH4 0.41 5.16 0.42 9.55e-7 Alcohol dependence; TGCT cis rs240764 0.853 rs12374612 chr6:100955752 C/T cg21058520 chr6:100914733 NA 0.35 4.56 0.38 1.19e-5 Neuroticism; TGCT cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.08e-7 Lymphocyte counts; TGCT cis rs9400467 0.506 rs12192718 chr6:111569151 T/A cg15721981 chr6:111408429 SLC16A10 0.7 4.46 0.37 1.83e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs1127311 0.901 rs11264223 chr1:154565519 G/A cg17218026 chr1:154582156 ADAR 0.31 7.75 0.57 2.86e-12 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs80282103 0.618 rs59377495 chr10:1157019 C/T cg08668510 chr10:1095578 IDI1 0.98 4.51 0.38 1.46e-5 Glomerular filtration rate (creatinine); TGCT cis rs769267 0.930 rs751856 chr19:19602945 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs2204008 0.776 rs8186824 chr12:38316537 A/C cg26384229 chr12:38710491 ALG10B 0.77 6.88 0.53 2.6200000000000003e-10 Bladder cancer; TGCT cis rs9952991 0.883 rs2542148 chr18:12777573 C/G cg09945482 chr18:12777974 NA 0.5 4.75 0.39 5.61e-6 Inflammatory skin disease; TGCT cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs3782455 1.000 rs16943528 chr12:114403582 A/C cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs3617 0.652 rs60332615 chr3:52867595 C/A cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7647973 1.000 rs2177268 chr3:49439725 A/T cg06212747 chr3:49208901 KLHDC8B -0.59 -4.72 -0.39 6.19e-6 Menarche (age at onset); TGCT cis rs1843834 0.734 rs1908251 chr2:225487865 T/C cg22455342 chr2:225449267 CUL3 0.79 7.98 0.58 8.35e-13 IgE levels in asthmatics (D.p. specific); TGCT cis rs2153535 0.580 rs9392220 chr6:8457946 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs8103278 0.864 rs2070737 chr19:46282890 A/T cg11657440 chr19:46296263 DMWD -0.58 -5.73 -0.46 7.03e-8 Coronary artery disease; TGCT cis rs67460515 0.859 rs7610800 chr3:161002582 C/T cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT cis rs9972944 0.756 rs6416948 chr17:63767131 T/G cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs986417 0.901 rs1010052 chr14:61003071 G/A cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg06634786 chr22:41940651 POLR3H -0.72 -6.68 -0.51 7.15e-10 Vitiligo; TGCT cis rs7552404 1.000 rs441109 chr1:76120430 T/G cg10523679 chr1:76189770 ACADM -0.93 -10.18 -0.67 4.69e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3820928 0.904 rs2396432 chr2:227765891 C/T cg11843606 chr2:227700838 RHBDD1 -0.51 -4.49 -0.37 1.59e-5 Pulmonary function; TGCT cis rs35934224 0.657 rs9606169 chr22:19856472 G/A cg11182965 chr22:19864308 TXNRD2 -0.36 -4.53 -0.38 1.34e-5 Glaucoma (primary open-angle); TGCT cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT trans rs1974653 0.672 rs112629076 chr22:20079688 T/C cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs981844 0.736 rs1036614 chr4:154639105 G/A cg14289246 chr4:154710475 SFRP2 0.98 7.59 0.56 6.55e-12 Response to statins (LDL cholesterol change); TGCT cis rs12541335 0.639 rs3923439 chr8:22170079 G/A cg02788857 chr8:22132959 PIWIL2 0.27 4.96 0.41 2.25e-6 Hypertriglyceridemia; TGCT cis rs1975974 0.511 rs17052375 chr17:21743877 G/A cg18423549 chr17:21743878 NA -0.69 -6.64 -0.51 8.59e-10 Psoriasis; TGCT cis rs7926906 0.846 rs10830578 chr11:90539319 A/G cg26138821 chr11:89956704 CHORDC1 -0.48 -5.07 -0.41 1.38e-6 Intelligence (multi-trait analysis); TGCT cis rs4727027 0.835 rs6959224 chr7:148784495 A/G cg23583168 chr7:148888333 NA -0.65 -8.05 -0.59 5.66e-13 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs453301 0.652 rs2043129 chr8:8825504 C/G cg06636001 chr8:8085503 FLJ10661 0.68 5.58 0.45 1.46e-7 Joint mobility (Beighton score); TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs1887596 0.630 rs1276045 chr13:27246216 T/C cg01312412 chr13:27282625 NA 0.28 5.01 0.41 1.79e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs9217 0.841 rs7225954 chr17:7397274 G/A cg17892169 chr17:7452644 TNFSF12;TNFSF12-TNFSF13 -0.23 -4.44 -0.37 1.99e-5 Height; TGCT cis rs6570726 0.577 rs867056 chr6:145784805 A/C cg13319975 chr6:146136371 FBXO30 0.65 5.75 0.46 6.54e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs1527517 chr4:98931907 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13118159 0.934 rs4974553 chr4:1356911 G/A cg22683308 chr4:1340831 KIAA1530 -0.66 -6.2 -0.49 7.68e-9 Longevity; TGCT cis rs3741151 0.892 rs3741152 chr11:73008914 G/A cg17517138 chr11:73019481 ARHGEF17 0.93 5.04 0.41 1.59e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs36051895 0.587 rs16922785 chr9:5200409 C/G cg02405213 chr9:5042618 JAK2 -0.72 -8.77 -0.62 1.14e-14 Pediatric autoimmune diseases; TGCT cis rs6860806 0.507 rs635620 chr5:131720263 A/G cg24060327 chr5:131705240 SLC22A5 0.77 8.48 0.61 5.57e-14 Breast cancer; TGCT cis rs7213347 0.780 rs170041 chr17:2170216 C/T cg20777128 chr17:1945076 DPH1;OVCA2 0.5 4.46 0.37 1.84e-5 Total body bone mineral density; TGCT cis rs7824557 0.602 rs7820895 chr8:11206262 T/C cg21775007 chr8:11205619 TDH 0.73 7.01 0.53 1.32e-10 Retinal vascular caliber; TGCT cis rs2463822 1.000 rs2513076 chr11:62103711 A/G cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9911578 1.000 rs12449365 chr17:56600660 C/G cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs2228479 0.867 rs12919804 chr16:89945369 G/A cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs3749237 0.595 rs4855873 chr3:49459114 A/C cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.47 -0.5 2.01e-9 Alzheimer's disease; TGCT cis rs611744 0.967 rs686251 chr8:109198907 C/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs9372498 0.505 rs62424202 chr6:118851027 T/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.8 -0.4 4.4e-6 Diastolic blood pressure; TGCT cis rs3812831 0.695 rs8000778 chr13:114944310 T/C cg08824895 chr13:115047677 UPF3A 0.51 4.99 0.41 1.98e-6 Schizophrenia; TGCT cis rs1801251 1.000 rs1446308 chr2:233639309 T/C cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs3020736 0.500 rs6002616 chr22:42504679 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7681440 0.904 rs28734152 chr4:90767359 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs782590 0.574 rs12991445 chr2:55675939 C/T cg03859395 chr2:55845619 SMEK2 0.61 5.35 0.43 4.07e-7 Metabolic syndrome; TGCT cis rs13256369 0.802 rs13256404 chr8:8562974 T/C cg18904891 chr8:8559673 CLDN23 0.58 5.4 0.44 3.23e-7 Obesity-related traits; TGCT cis rs2832191 0.755 rs2832193 chr21:30493589 T/C cg24692254 chr21:30365293 RNF160 -0.91 -9.65 -0.65 8.88e-17 Dental caries; TGCT cis rs950776 0.518 rs12906284 chr15:78825105 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs3617 0.625 rs7612624 chr3:52893426 T/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.49 -4.58 -0.38 1.09e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs789852 1.000 rs711980 chr3:194324558 G/C cg18000598 chr3:194342907 TMEM44 -0.81 -5.31 -0.43 4.83e-7 QT interval; TGCT cis rs1670533 1.000 rs10026482 chr4:1051128 C/G cg27284194 chr4:1044797 NA 0.68 5.87 0.47 3.76e-8 Recombination rate (females); TGCT cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg11644478 chr21:40555479 PSMG1 -0.6 -5.65 -0.45 1.03e-7 Cognitive function; TGCT cis rs72634258 0.945 rs12727642 chr1:8046672 C/A cg23986158 chr1:8847014 RERE 0.28 4.51 0.38 1.47e-5 Inflammatory bowel disease; TGCT cis rs9467773 1.000 rs10214634 chr6:26564582 T/A cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.803 rs10831140 chr11:93640689 G/A cg16099599 chr11:93583650 C11orf90 -0.39 -4.78 -0.39 4.94e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs114540395 0.858 rs3730467 chr10:103342783 G/T cg10198749 chr1:39920707 MACF1 0.55 7.06 0.54 1.06e-10 Schizophrenia; TGCT cis rs28374715 0.783 rs1866399 chr15:41571139 G/A cg18705301 chr15:41695430 NDUFAF1 -0.83 -11.36 -0.71 6.08e-21 Ulcerative colitis; TGCT cis rs735396 0.627 rs2264778 chr12:121450354 C/A cg15155738 chr12:121454335 C12orf43 0.62 5.59 0.45 1.39e-7 N-glycan levels; TGCT cis rs4665809 1.000 rs4665305 chr2:26313524 C/T cg04944784 chr2:26401820 FAM59B -0.68 -6.04 -0.48 1.7e-8 Gut microbiome composition (summer); TGCT cis rs1008375 0.900 rs13144986 chr4:17675019 C/A cg18681998 chr4:17616180 MED28 -0.86 -8.72 -0.62 1.53e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs57506017 0.585 rs5011437 chr7:12268792 A/T cg07541786 chr7:12610355 SCIN 0.45 4.58 0.38 1.12e-5 Neuroticism; TGCT cis rs9611519 0.929 rs9611466 chr22:41426299 A/T cg13695892 chr22:41940480 POLR3H -0.53 -4.62 -0.38 9.54e-6 Neuroticism; TGCT cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg10047753 chr17:41438598 NA 0.91 8.44 0.6 6.86e-14 Menopause (age at onset); TGCT cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg08280861 chr8:58055591 NA 0.37 5.03 0.41 1.66e-6 Developmental language disorder (linguistic errors); TGCT cis rs10507380 0.824 rs9512633 chr13:27919246 C/T cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs9611565 0.921 rs4822021 chr22:41726053 G/A cg13695892 chr22:41940480 POLR3H -0.76 -7.25 -0.55 3.83e-11 Vitiligo; TGCT cis rs7568458 0.709 rs2592551 chr2:85780131 G/A cg02493740 chr2:85810744 VAMP5 -0.28 -5.37 -0.43 3.67e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs651907 0.514 rs34301719 chr3:101417993 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 9.87 0.66 2.65e-17 Colorectal cancer; TGCT cis rs727505 0.954 rs1383748 chr7:124638201 A/T cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs9394169 0.709 rs6919321 chr6:33724004 G/A cg13859433 chr6:33739653 LEMD2 -0.33 -5.52 -0.44 1.93e-7 Essential tremor; TGCT cis rs60871478 0.636 rs10245785 chr7:894422 T/C cg15782153 chr7:917662 C7orf20 0.54 4.92 0.4 2.74e-6 Cerebrospinal P-tau181p levels; TGCT cis rs9952991 0.883 rs2847260 chr18:12775591 C/T cg23544223 chr18:12777786 NA 0.63 6.02 0.48 1.85e-8 Inflammatory skin disease; TGCT cis rs4794202 0.629 rs7214694 chr17:45895353 C/T cg02219949 chr17:45927392 SP6 0.39 4.45 0.37 1.93e-5 Alzheimer's disease (cognitive decline); TGCT cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg13395646 chr4:1353034 KIAA1530 -0.38 -4.72 -0.39 6.28e-6 Obesity-related traits; TGCT cis rs34526934 0.566 rs34028621 chr2:177042779 C/T cg00278547 chr2:177037212 HOXD3 -0.36 -4.45 -0.37 1.85e-5 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs7714584 1.000 rs10053750 chr5:150270051 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs775227 0.528 rs775231 chr3:113027214 A/C cg18753928 chr3:113234510 CCDC52 0.64 4.91 0.4 2.77e-6 Dental caries; TGCT cis rs2486012 1.000 rs2428963 chr1:44373439 C/T cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs10431058 0.930 rs7948142 chr11:107478703 T/G cg18204760 chr11:107461044 ELMOD1;LOC643923 0.72 6.9 0.53 2.36e-10 Common traits (Other); TGCT cis rs77372450 0.515 rs2277948 chr5:157098233 T/C cg19063654 chr5:156516798 HAVCR2 -0.37 -4.6 -0.38 1.02e-5 Bipolar disorder (body mass index interaction); TGCT cis rs36051895 0.623 rs11506292 chr9:5257048 C/A cg02405213 chr9:5042618 JAK2 -0.71 -8.41 -0.6 8.29e-14 Pediatric autoimmune diseases; TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg22166914 chr1:53195759 ZYG11B 0.36 5.71 0.46 8.05e-8 Monocyte count; TGCT cis rs7095607 0.654 rs7081017 chr10:69954451 A/G cg18986048 chr10:69913749 MYPN 0.56 6.0 0.47 2e-8 Lung function (FVC); TGCT cis rs2658782 0.901 rs11604909 chr11:93218355 C/G cg18152523 chr11:93063302 CCDC67 -0.67 -5.6 -0.45 1.3e-7 Pulmonary function decline; TGCT cis rs7845219 0.544 rs34293080 chr8:95908078 G/T cg16049864 chr8:95962084 TP53INP1 -0.5 -5.39 -0.44 3.35e-7 Type 2 diabetes; TGCT cis rs12210905 0.688 rs72843177 chr6:27367414 A/G cg08851530 chr6:28072375 NA 1.33 5.85 0.47 4.08e-8 Hip circumference adjusted for BMI; TGCT cis rs2677744 0.626 rs11857545 chr15:91489705 G/A cg23684204 chr15:91497937 RCCD1 0.36 5.37 0.43 3.79e-7 Attention deficit hyperactivity disorder; TGCT cis rs7547997 0.615 rs73029766 chr1:158320989 G/A cg03528325 chr1:158223921 CD1A 0.34 4.71 0.39 6.65e-6 QRS duration; TGCT cis rs9549367 0.789 rs12584008 chr13:113881228 C/T cg00898013 chr13:113819073 PROZ -0.4 -4.88 -0.4 3.18e-6 Platelet distribution width; TGCT cis rs4389656 0.857 rs416847 chr5:6739567 A/G cg10857441 chr5:6722123 POLS -0.22 -4.76 -0.39 5.28e-6 Coronary artery disease; TGCT cis rs9419702 0.568 rs9419635 chr10:133546164 C/T cg04492858 chr10:133558786 NA 0.57 6.06 0.48 1.52e-8 Survival in rectal cancer; TGCT cis rs6570726 0.846 rs441575 chr6:145849205 A/C cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3015497 0.934 rs2934691 chr14:51121333 C/A cg04730355 chr14:51134070 SAV1 -0.52 -4.6 -0.38 1.01e-5 Mean platelet volume; TGCT cis rs9894429 1.000 rs7223613 chr17:79574803 C/T cg18240062 chr17:79603768 NPLOC4 -0.67 -6.84 -0.52 3.23e-10 Eye color traits; TGCT cis rs17221829 0.673 rs10830324 chr11:89388845 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg24549020 chr5:56110836 MAP3K1 0.63 5.5 0.44 2.05e-7 Initial pursuit acceleration; TGCT cis rs1775715 0.737 rs1419171 chr10:32214831 C/A cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs10875746 0.625 rs2898065 chr12:48644619 C/A cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT cis rs7267979 1.000 rs4815408 chr20:25346678 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg12311346 chr5:56204834 C5orf35 -0.68 -6.87 -0.52 2.83e-10 Type 2 diabetes; TGCT cis rs7617773 0.539 rs6779517 chr3:48384388 C/T cg11946769 chr3:48343235 NME6 0.6 5.09 0.42 1.28e-6 Coronary artery disease; TGCT cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs36051895 0.659 rs7859390 chr9:5062473 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.42 -0.65 3.29e-16 Pediatric autoimmune diseases; TGCT cis rs7017914 0.967 rs34409123 chr8:71662116 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs13223928 0.651 rs4722435 chr7:3152962 C/T cg19214707 chr7:3157722 NA 0.49 7.05 0.53 1.09e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs1008375 1.000 rs1860596 chr4:17660082 C/T cg10189774 chr4:17578691 LAP3 0.56 4.95 0.41 2.39e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2836633 0.895 rs2836597 chr21:40024424 A/G cg12884169 chr21:40033163 ERG 0.44 4.64 0.38 8.68e-6 Coronary artery disease; TGCT cis rs4319547 0.737 rs10773176 chr12:122944713 A/G cg05707623 chr12:122985044 ZCCHC8 -0.63 -4.94 -0.41 2.49e-6 Body mass index; TGCT cis rs16966142 0.786 rs2238533 chr16:89871344 T/C cg03388025 chr16:89894329 SPIRE2 0.46 4.46 0.37 1.81e-5 Caffeine consumption; TGCT cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg10207240 chr12:122356781 WDR66 -0.37 -5.31 -0.43 4.95e-7 Mean corpuscular volume; TGCT cis rs17102423 0.588 rs7150646 chr14:65540463 G/T cg11161011 chr14:65562177 MAX -0.46 -6.54 -0.51 1.45e-9 Obesity-related traits; TGCT cis rs3540 0.960 rs1505936 chr15:91010776 T/C cg22089800 chr15:90895588 ZNF774 0.74 6.74 0.52 5.32e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs916888 0.773 rs199533 chr17:44828931 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.81 5.6 0.45 1.32e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7772486 0.754 rs4896839 chr6:146019689 T/G cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2228479 0.867 rs12930606 chr16:89946682 A/G cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT trans rs797680 0.822 rs7541304 chr1:93757838 T/A cg27528825 chr2:159282178 CCDC148 0.34 6.71 0.52 6.32e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs79724016 0.744 rs7539225 chr1:42113523 A/G cg14093106 chr1:42503579 NA -0.63 -4.51 -0.38 1.47e-5 Breast cancer; TGCT cis rs3849570 1.000 rs3860595 chr3:81811784 A/G cg07356753 chr3:81810745 GBE1 -0.68 -5.75 -0.46 6.51e-8 Waist circumference;Body mass index; TGCT cis rs2075371 1.000 rs2598296 chr7:133992985 C/T cg11752832 chr7:134001865 SLC35B4 0.69 6.26 0.49 5.87e-9 Mean platelet volume; TGCT cis rs4654899 0.802 rs57351360 chr1:21229538 T/A cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs9549260 0.564 rs7997896 chr13:41268823 T/A cg21288729 chr13:41239152 FOXO1 0.92 8.97 0.63 3.82e-15 Red blood cell count; TGCT cis rs265548 0.538 rs36688 chr19:17911212 A/C cg04517722 chr19:17905589 B3GNT3 0.47 6.31 0.49 4.46e-9 Tumor biomarkers; TGCT cis rs2120019 0.938 rs8036573 chr15:75308690 C/T cg09165964 chr15:75287851 SCAMP5 -1.18 -10.31 -0.68 2.22e-18 Blood trace element (Zn levels); TGCT cis rs2204008 0.774 rs11180977 chr12:38263094 G/T cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs10876993 0.928 rs2169988 chr12:58071165 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.83 -0.46 4.52e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs6540234 0.701 rs9933690 chr16:85993295 T/C cg01145317 chr16:86542838 FOXF1 0.48 4.44 0.37 1.96e-5 Granulocyte percentage of myeloid white cells;Monocyte count; TGCT cis rs587847 0.540 rs668644 chr15:37669606 G/A cg16890051 chr15:37175029 LOC145845 -0.38 -4.49 -0.37 1.6e-5 Intraocular pressure; TGCT cis rs7264396 0.779 rs2425162 chr20:34429974 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.74 -0.39 5.7e-6 Total cholesterol levels; TGCT cis rs12497850 0.931 rs9311433 chr3:48863835 T/C cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs79976124 0.842 rs1548154 chr6:66624910 G/A cg07460842 chr6:66804631 NA 0.6 5.3 0.43 5.2e-7 Type 2 diabetes; TGCT cis rs6845621 0.600 rs35850168 chr4:18913277 T/A cg12196642 chr4:18937545 NA -0.25 -4.48 -0.37 1.69e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs6556937 0.562 rs31248 chr5:96014683 A/G cg01741836 chr5:95996644 CAST 0.33 4.52 0.38 1.45e-5 Blood protein levels; TGCT cis rs1008375 0.966 rs2302393 chr4:17654341 G/A cg18681998 chr4:17616180 MED28 1.0 11.67 0.72 1.11e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7927592 0.513 rs901823 chr11:68205578 T/C cg16797656 chr11:68205561 LRP5 0.32 5.62 0.45 1.22e-7 Total body bone mineral density; TGCT cis rs17270561 0.562 rs12199626 chr6:26013604 G/A cg17691542 chr6:26056736 HIST1H1C 0.99 6.89 0.53 2.55e-10 Iron status biomarkers; TGCT cis rs6940638 0.662 rs6915678 chr6:27235866 T/G cg05738196 chr6:26577821 NA -0.53 -4.74 -0.39 5.81e-6 Intelligence (multi-trait analysis); TGCT cis rs8033133 1.000 rs8033133 chr15:25350474 A/G cg14481604 chr15:25334117 SNORD116-22 -0.31 -6.42 -0.5 2.67e-9 Blood osmolality (transformed sodium); TGCT cis rs7666738 0.830 rs28622458 chr4:98916651 A/G cg05340658 chr4:99064831 C4orf37 0.54 6.51 0.5 1.7e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg14893161 chr1:205819251 PM20D1 0.57 8.22 0.59 2.36e-13 Menarche (age at onset); TGCT cis rs9906944 0.545 rs2088140 chr17:47094599 T/C cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.51 -0.38 1.47e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7264396 0.690 rs2425171 chr20:34443173 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs2816062 0.786 rs742486 chr1:18900829 G/A cg18795169 chr1:18902165 NA -0.6 -13.92 -0.78 4.23e-27 Urate levels in lean individuals; TGCT cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg13695892 chr22:41940480 POLR3H 0.78 7.62 0.56 5.73e-12 Vitiligo; TGCT cis rs4824093 0.545 rs58876234 chr22:50258868 G/A cg20569369 chr22:51173646 NA 0.28 4.69 0.39 7.23e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs554111 0.656 rs12021529 chr1:21306161 C/T cg01072550 chr1:21505969 NA -0.32 -4.99 -0.41 2.03e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg23205692 chr1:25664452 TMEM50A 0.45 4.78 0.39 4.77e-6 Erythrocyte sedimentation rate; TGCT cis rs9291683 0.525 rs12506455 chr4:10031569 T/A cg00071950 chr4:10020882 SLC2A9 0.68 8.84 0.62 7.71e-15 Bone mineral density; TGCT cis rs10782582 0.609 rs56159153 chr1:76353498 T/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs875971 1.000 rs4717300 chr7:65947380 T/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs11992186 0.597 rs77717027 chr8:8591632 T/C cg15556689 chr8:8085844 FLJ10661 -0.55 -4.67 -0.39 7.8e-6 Neuroticism; TGCT cis rs10465746 0.780 rs1324486 chr1:84384825 A/G cg10977910 chr1:84465055 TTLL7 -0.71 -7.16 -0.54 6.15e-11 Obesity-related traits; TGCT cis rs73001065 0.901 rs10401969 chr19:19407718 A/G cg03709012 chr19:19516395 GATAD2A 1.01 5.04 0.41 1.6e-6 LDL cholesterol; TGCT cis rs6460942 0.915 rs62448598 chr7:12453762 T/C cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs1577917 0.771 rs7762321 chr6:86412146 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 4.63 0.38 9.12e-6 Response to antipsychotic treatment; TGCT cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg11644478 chr21:40555479 PSMG1 -0.56 -5.23 -0.42 7.09e-7 Menarche (age at onset); TGCT cis rs6695640 0.854 rs1555660 chr1:17731117 T/C cg25979543 chr1:17888104 ARHGEF10L -0.25 -4.57 -0.38 1.14e-5 Mean platelet volume; TGCT cis rs9677476 0.516 rs7607338 chr2:231987955 C/A cg27665808 chr2:232055229 NA 0.36 4.5 0.37 1.52e-5 Food antigen IgG levels; TGCT cis rs1887596 0.639 rs581728 chr13:27202054 T/A cg01312412 chr13:27282625 NA 0.29 5.13 0.42 1.1e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg18654377 chr3:49208889 KLHDC8B -0.39 -5.04 -0.41 1.6e-6 Menarche (age at onset); TGCT cis rs1552244 0.882 rs68080705 chr3:10025743 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg06238570 chr21:40685208 BRWD1 0.72 6.58 0.51 1.16e-9 Cognitive function; TGCT cis rs1568889 1.000 rs12796293 chr11:28177723 C/T cg06544937 chr11:28130018 METT5D1;KIF18A -0.83 -8.75 -0.62 1.26e-14 Bipolar disorder; TGCT cis rs13191362 1.000 rs13213408 chr6:162998049 A/T cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9557207 1.000 rs9557192 chr13:99944165 C/T cg24509225 chr13:100037070 UBAC2 -0.23 -4.55 -0.38 1.26e-5 Peripheral arterial disease (traffic-related air pollution interaction);Inflammatory bowel disease; TGCT cis rs11148252 0.904 rs9568732 chr13:52993412 A/G cg00495681 chr13:53174319 NA -0.57 -5.97 -0.47 2.37e-8 Lewy body disease; TGCT cis rs9357506 0.905 rs4714928 chr6:46309843 T/C cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs1023500 0.552 rs133368 chr22:42463689 T/C cg15557168 chr22:42548783 NA -0.22 -5.6 -0.45 1.33e-7 Schizophrenia; TGCT cis rs514406 0.861 rs35581164 chr1:53271373 C/G cg24675658 chr1:53192096 ZYG11B -0.7 -7.96 -0.58 9.19e-13 Monocyte count; TGCT cis rs28374715 0.662 rs28493087 chr15:41486504 G/A cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.6 -0.72 1.65e-21 Ulcerative colitis; TGCT cis rs2836950 0.565 rs8134214 chr21:40542367 A/C cg11890956 chr21:40555474 PSMG1 -0.69 -6.59 -0.51 1.13e-9 Menarche (age at onset); TGCT cis rs71435601 0.600 rs544450 chr2:21384358 T/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs7208859 0.673 rs55658077 chr17:29156519 A/G cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs35883536 0.647 rs10875315 chr1:101044062 G/A cg10298815 chr1:101004474 GPR88 -0.24 -4.44 -0.37 1.95e-5 Monocyte count; TGCT cis rs2303745 0.589 rs1465576 chr19:17398487 G/A cg02221750 chr19:17393354 ANKLE1 -0.46 -5.81 -0.46 5.05e-8 Systemic lupus erythematosus; TGCT cis rs7772486 0.641 rs9390374 chr6:146368175 A/T cg23711669 chr6:146136114 FBXO30 0.71 6.86 0.52 2.89e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7809950 0.678 rs12672451 chr7:106853817 C/G cg23024343 chr7:107201750 COG5 -0.43 -5.84 -0.46 4.2e-8 Coronary artery disease; TGCT cis rs4733781 0.509 rs6470811 chr8:131338933 G/T cg16277922 chr8:131349729 ASAP1 -0.53 -8.76 -0.62 1.24e-14 Tuberculosis; TGCT cis rs6570726 0.764 rs366673 chr6:145814628 T/A cg23711669 chr6:146136114 FBXO30 0.89 9.73 0.66 5.62e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9892942 1 rs9892942 chr17:27178761 C/T cg06745955 chr17:27038470 PROCA1 -0.58 -4.55 -0.38 1.27e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs10089 0.680 rs3805616 chr5:127520897 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.86 7.0 0.53 1.41e-10 Ileal carcinoids; TGCT cis rs11098499 0.954 rs3733523 chr4:120423719 C/T cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs9611565 0.559 rs5751160 chr22:42175695 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs1799949 0.930 rs33968979 chr17:41297992 G/T cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs13326165 0.760 rs2016575 chr3:52477080 T/C cg07884673 chr3:53033167 SFMBT1 -0.39 -4.69 -0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs4711350 0.765 rs943473 chr6:33743651 G/C cg13859433 chr6:33739653 LEMD2 -0.33 -4.98 -0.41 2.12e-6 Schizophrenia; TGCT cis rs13067306 1.000 rs13087299 chr3:94229344 T/C cg16274205 chr3:94243571 NA 0.32 4.68 0.39 7.38e-6 Blood pressure measurement (high sodium intervention); TGCT cis rs2777491 0.915 rs8032838 chr15:41605632 G/A cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.44 -0.68 1.07e-18 Ulcerative colitis; TGCT cis rs9467711 0.516 rs555460 chr6:25870655 C/T cg03264133 chr6:25882463 NA -0.71 -4.82 -0.4 4.07e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1357245 0.534 rs6766181 chr3:27100290 A/G cg02860705 chr3:27208620 NA -0.31 -5.02 -0.41 1.73e-6 Breast cancer; TGCT cis rs7043114 0.525 rs7863406 chr9:95053381 T/C cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.95e-5 Height; TGCT cis rs793571 0.590 rs442495 chr15:59022615 T/C cg05156742 chr15:59063176 FAM63B 0.47 4.48 0.37 1.7e-5 Schizophrenia; TGCT cis rs2836974 0.583 rs2735307 chr21:40713358 C/T cg11644478 chr21:40555479 PSMG1 0.65 6.27 0.49 5.38e-9 Cognitive function; TGCT cis rs7772486 0.790 rs9485024 chr6:146142487 A/G cg05347473 chr6:146136440 FBXO30 -0.49 -4.78 -0.39 4.92e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1215050 0.791 rs165239 chr4:98682549 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.51 0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12971120 0.891 rs2278158 chr18:72178300 G/T cg26446133 chr18:72167187 CNDP2 -0.35 -5.89 -0.47 3.42e-8 Refractive error; TGCT cis rs12681287 0.604 rs34227066 chr8:87449366 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs72627509 0.680 rs73165962 chr4:57740533 G/A cg26694713 chr4:57773883 REST 0.82 6.68 0.51 7.07e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6598955 0.627 rs6684875 chr1:26567044 A/G cg04990556 chr1:26633338 UBXN11 0.64 5.11 0.42 1.19e-6 Obesity-related traits; TGCT cis rs11734570 0.581 rs73811716 chr4:38590773 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.65 4.96 0.41 2.24e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs11718455 0.767 rs9861276 chr3:43989595 C/T cg08738300 chr3:44038990 NA 0.74 5.62 0.45 1.22e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs1025204 chr4:99023441 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.51 0.44 2.01e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.39 5.24 0.43 6.78e-7 Lymphocyte counts; TGCT cis rs4478858 0.735 rs6681286 chr1:31799384 G/C cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs9611519 0.780 rs2235852 chr22:41661154 G/T cg13695892 chr22:41940480 POLR3H -0.68 -4.8 -0.4 4.55e-6 Neuroticism; TGCT cis rs1048238 0.506 rs10927867 chr1:16177285 A/G cg21385522 chr1:16154831 NA 0.58 6.5 0.5 1.72e-9 Systolic blood pressure; TGCT cis rs9364220 0.623 rs6940507 chr6:168493719 T/C cg02770688 chr6:168491649 NA -0.3 -5.51 -0.44 2.02e-7 Attention deficit hyperactivity disorder (inattention symptoms);Attention deficit hyperactivity disorder (combined symptoms); TGCT cis rs10779751 0.734 rs6701726 chr1:11126941 C/T cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs1008375 0.618 rs13129002 chr4:17567513 A/G cg16339924 chr4:17578868 LAP3 0.7 5.82 0.46 4.63e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6840360 0.638 rs2406974 chr4:152601841 G/A cg22705602 chr4:152727874 NA -0.33 -5.5 -0.44 2.11e-7 Intelligence (multi-trait analysis); TGCT cis rs933688 1.000 rs9293568 chr5:90737845 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.49 0.61 5.31e-14 Smoking behavior; TGCT cis rs6840360 0.642 rs1899550 chr4:152407236 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs546131 0.928 rs558967 chr11:34827168 T/A cg06937548 chr11:34938143 PDHX;APIP 0.65 5.91 0.47 3.14e-8 Lung disease severity in cystic fibrosis; TGCT cis rs45509595 0.822 rs200484 chr6:27775674 A/G cg08798685 chr6:27730294 NA -0.33 -4.53 -0.38 1.34e-5 Breast cancer; TGCT cis rs12188164 0.965 rs77101200 chr5:443059 G/T cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.61e-6 Cystic fibrosis severity; TGCT cis rs7523273 0.606 rs2796283 chr1:207978732 C/T cg22525895 chr1:207977042 MIR29B2 -0.55 -9.57 -0.65 1.36e-16 Schizophrenia; TGCT cis rs9467711 0.790 rs13195402 chr6:26463575 G/T cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs79387448 0.745 rs723292 chr2:103166804 A/G cg09003973 chr2:102972529 NA 0.95 6.15 0.48 9.95e-9 Gut microbiota (bacterial taxa); TGCT cis rs236907 0.812 rs17596025 chr1:171746247 T/C cg20598894 chr1:171756153 METTL13 -0.19 -4.52 -0.38 1.42e-5 Mean platelet volume; TGCT cis rs12950390 0.814 rs4794099 chr17:45838358 T/C cg06532163 chr17:45867833 NA 0.34 5.31 0.43 4.82e-7 IgG glycosylation; TGCT cis rs79349575 0.811 rs60708039 chr17:46999373 C/G cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs875971 0.564 rs313804 chr7:65514622 A/G cg11764359 chr7:65958608 NA 0.54 4.66 0.39 7.88e-6 Aortic root size; TGCT cis rs9650657 0.589 rs6985109 chr8:10761585 A/G cg27411982 chr8:10470053 RP1L1 0.21 4.51 0.38 1.51e-5 Neuroticism; TGCT cis rs1372520 0.748 rs990085 chr4:90754771 A/G cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs7264396 0.561 rs6060750 chr20:34596371 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -5.02 -0.41 1.79e-6 Total cholesterol levels; TGCT cis rs67311347 1.000 rs1047855 chr3:40468896 A/G cg13409248 chr3:40428643 ENTPD3 -0.55 -4.47 -0.37 1.74e-5 Renal cell carcinoma; TGCT cis rs7611238 0.583 rs11706218 chr3:195055790 A/T cg27323046 chr3:195102265 ACAP2 0.37 4.9 0.4 2.9e-6 Body mass index; TGCT cis rs2243480 1.000 rs1267820 chr7:66050295 C/G cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs10986311 0.713 rs10986292 chr9:127016876 T/G cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.57 -0.38 1.15e-5 Vitiligo; TGCT trans rs2727020 0.595 rs10466496 chr11:49501514 C/T cg15704280 chr7:45808275 SEPT13 -0.74 -8.49 -0.61 5.28e-14 Coronary artery disease; TGCT cis rs921968 0.648 rs538483 chr2:219458656 T/C cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs6500602 0.702 rs17761816 chr16:4548832 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.65 0.45 1.06e-7 Schizophrenia; TGCT cis rs10170846 0.572 rs12620873 chr2:223419528 A/C cg25565276 chr2:223520875 FARSB 0.86 5.92 0.47 2.93e-8 Schizophrenia (inflammation and infection response interaction); TGCT cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg20637647 chr7:64974828 NA 0.88 5.34 0.43 4.19e-7 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs17550610 chr4:99008273 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4788570 0.584 rs7204608 chr16:71678679 C/G cg06353428 chr16:71660113 MARVELD3 -1.51 -11.87 -0.73 3.6e-22 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg03517284 chr6:25882590 NA -0.65 -5.87 -0.47 3.78e-8 Intelligence (multi-trait analysis); TGCT cis rs12541335 0.639 rs6993855 chr8:22163797 A/G cg18135555 chr8:22132992 PIWIL2 0.29 5.69 0.45 8.74e-8 Hypertriglyceridemia; TGCT cis rs344364 0.511 rs62040569 chr16:1948137 C/T cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs1215050 0.791 rs11729826 chr4:98657190 G/T cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9868809 0.772 rs12107418 chr3:48689787 A/G cg00383909 chr3:49044727 WDR6 0.9 5.42 0.44 3.05e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9926296 0.632 rs2011925 chr16:89814064 T/G cg26513180 chr16:89883248 FANCA 0.73 6.92 0.53 2.1e-10 Vitiligo; TGCT cis rs9300255 0.739 rs4759371 chr12:123742563 T/C cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs1153858 0.621 rs2687512 chr15:45581495 T/C cg14582100 chr15:45693742 SPATA5L1 -0.48 -5.28 -0.43 5.67e-7 Homoarginine levels; TGCT cis rs12497850 0.897 rs6781790 chr3:49044767 C/T cg05785598 chr3:49045655 WDR6 0.36 4.77 0.39 5.17e-6 Parkinson's disease; TGCT cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg15659132 chr6:26577336 NA 0.84 10.91 0.7 7.83e-20 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.615 rs7669761 chr4:152609304 G/A cg22705602 chr4:152727874 NA -0.32 -5.44 -0.44 2.76e-7 Intelligence (multi-trait analysis); TGCT cis rs595982 0.702 rs609985 chr19:49370648 A/G cg21252483 chr19:49399788 TULP2 -0.26 -4.48 -0.37 1.67e-5 Red cell distribution width; TGCT cis rs4233949 0.832 rs6734097 chr2:54651933 C/T cg14634210 chr2:54682758 SPTBN1 0.58 4.83 0.4 3.97e-6 Bone mineral density; TGCT cis rs9902453 0.967 rs56326816 chr17:28492805 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs1153858 1.000 rs12440038 chr15:45706739 A/G cg26924012 chr15:45694286 SPATA5L1 1.1 15.34 0.81 2.01e-30 Homoarginine levels; TGCT trans rs2469997 1.000 rs2447168 chr8:120365613 A/T cg01792902 chr3:178864926 PIK3CA 0.78 6.64 0.51 8.85e-10 Hypertension (SNP x SNP interaction); TGCT cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.55 -5.41 -0.44 3.15e-7 Intelligence (multi-trait analysis); TGCT cis rs362296 0.661 rs3095078 chr4:3265479 C/T cg06533319 chr4:3265114 C4orf44 0.23 4.52 0.38 1.43e-5 Parental longevity (mother's age at death); TGCT cis rs4285028 0.747 rs7647351 chr3:121422109 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs7617773 0.817 rs13100815 chr3:48287449 A/C cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.64e-10 Coronary artery disease; TGCT cis rs611744 0.647 rs2298603 chr8:109271426 C/T cg21045802 chr8:109455806 TTC35 0.67 6.99 0.53 1.53e-10 Dupuytren's disease; TGCT cis rs9929218 1.000 rs13333528 chr16:68790502 C/T cg01251360 chr16:68772225 CDH1 0.29 4.89 0.4 3.01e-6 Colorectal cancer; TGCT cis rs4975709 0.589 rs4975707 chr5:1864028 C/T cg14773178 chr5:1868261 NA 0.35 6.17 0.48 9.08e-9 Cardiovascular disease risk factors; TGCT cis rs7698623 0.850 rs4693894 chr4:88797798 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs2836974 0.897 rs13339986 chr21:40605982 T/C cg06238570 chr21:40685208 BRWD1 0.61 5.44 0.44 2.79e-7 Cognitive function; TGCT cis rs12950390 0.853 rs11655336 chr17:45858836 A/G cg03474202 chr17:45855739 NA 0.44 4.64 0.38 8.66e-6 IgG glycosylation; TGCT cis rs514406 0.547 rs377808 chr1:53190359 T/G cg04995860 chr1:53192072 ZYG11B -0.41 -4.61 -0.38 1e-5 Monocyte count; TGCT cis rs8180040 0.627 rs6442059 chr3:47187075 C/G cg27129171 chr3:47204927 SETD2 0.71 8.5 0.61 5.06e-14 Colorectal cancer; TGCT cis rs9503598 1.000 rs9503598 chr6:3446263 A/G cg00476032 chr6:3446245 SLC22A23 -0.18 -5.37 -0.43 3.79e-7 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); TGCT cis rs2836974 0.831 rs34592564 chr21:40516288 G/C cg17971929 chr21:40555470 PSMG1 0.95 9.06 0.63 2.31e-15 Cognitive function; TGCT cis rs514406 0.825 rs6693210 chr1:53223398 A/G cg01802117 chr1:53393560 SCP2 0.43 5.14 0.42 1.02e-6 Monocyte count; TGCT cis rs9914988 0.943 rs2874253 chr17:27157863 A/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2070856 0.655 rs6049057 chr20:23725528 A/G cg07394064 chr20:23346232 GZF1 0.44 4.58 0.38 1.09e-5 Blood protein levels; TGCT cis rs763121 0.853 rs4821808 chr22:39065739 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs35146811 0.735 rs11764176 chr7:99786964 G/T cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs11190604 1.000 rs11292 chr10:102313607 A/G cg23241863 chr10:102295624 HIF1AN 0.66 4.99 0.41 2.01e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4722166 0.568 rs1880241 chr7:22759469 A/G cg26061582 chr7:22766209 IL6 0.37 4.93 0.41 2.54e-6 Lung cancer; TGCT cis rs9653442 0.564 rs4850924 chr2:100782273 A/G cg07810366 chr2:100720526 AFF3 -0.35 -5.1 -0.42 1.26e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2948294 0.566 rs13274039 chr8:8111659 A/G cg06636001 chr8:8085503 FLJ10661 0.82 6.7 0.52 6.46e-10 Red cell distribution width; TGCT cis rs854572 0.600 rs854570 chr7:94952692 C/A cg21856205 chr7:94953877 PON1 0.62 7.12 0.54 7.72e-11 Paraoxonase activity; TGCT cis rs6570726 0.837 rs636894 chr6:145864122 T/C cg05347473 chr6:146136440 FBXO30 0.49 4.51 0.38 1.46e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9682041 0.932 rs1525362 chr3:170070702 C/T cg11886554 chr3:170076028 SKIL 0.71 5.62 0.45 1.2e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs7412746 0.658 rs12405726 chr1:150956128 G/A cg04414720 chr1:150670196 GOLPH3L 0.4 4.85 0.4 3.66e-6 Melanoma; TGCT cis rs12477438 0.765 rs7591794 chr2:99567514 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.6 -5.24 -0.43 6.6e-7 Chronic sinus infection; TGCT cis rs73058052 0.709 rs10416310 chr19:50079846 G/A cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.85 0.46 4.13e-8 Fibrinogen levels; TGCT cis rs10791097 0.694 rs7942621 chr11:130751308 C/G cg14779329 chr11:130786720 SNX19 0.29 5.01 0.41 1.85e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7586879 0.616 rs6545809 chr2:25126715 C/T cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs9303401 0.659 rs62081316 chr17:56781499 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs8044995 0.501 rs73613999 chr16:68390099 C/A cg05110241 chr16:68378359 PRMT7 -0.36 -4.45 -0.37 1.89e-5 Schizophrenia; TGCT cis rs2147959 0.882 rs4653552 chr1:228628138 A/G cg22700015 chr1:228743131 NA -0.57 -4.53 -0.38 1.35e-5 Adult asthma; TGCT cis rs6089584 0.507 rs28545731 chr20:60634102 C/T cg13770153 chr20:60521292 NA -0.43 -5.24 -0.43 6.83e-7 Body mass index; TGCT cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg18876405 chr7:65276391 NA 0.38 5.89 0.47 3.4e-8 Calcium levels; TGCT cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7552167 1.000 rs7552167 chr1:24518643 A/G cg01960748 chr1:24522592 NA -0.53 -5.83 -0.46 4.54e-8 Psoriasis vulgaris; TGCT cis rs981844 0.714 rs6853529 chr4:154706267 C/T cg14289246 chr4:154710475 SFRP2 0.77 5.87 0.47 3.77e-8 Response to statins (LDL cholesterol change); TGCT cis rs12188164 1.000 rs55842567 chr5:437586 G/A cg26850624 chr5:429559 AHRR -0.2 -4.82 -0.4 4.05e-6 Cystic fibrosis severity; TGCT cis rs9899728 0.539 rs113775187 chr17:73047290 A/G cg27626185 chr17:73056755 KCTD2 -0.92 -8.01 -0.58 7.17e-13 Alzheimer's disease or small vessel stroke; TGCT cis rs1153858 1.000 rs7171577 chr15:45627979 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs11031096 0.711 rs61899755 chr11:4201317 G/T cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6500602 0.826 rs7205189 chr16:4460114 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.39 0.5 3.09e-9 Schizophrenia; TGCT cis rs7917772 0.536 rs3961456 chr10:104425304 A/T cg05855489 chr10:104503620 C10orf26 0.57 4.74 0.39 5.82e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs3780486 0.757 rs10813949 chr9:33123464 G/A cg20290983 chr6:43655470 MRPS18A 1.17 14.54 0.79 1.43e-28 IgG glycosylation; TGCT cis rs2153535 0.580 rs9405391 chr6:8466548 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4986172 0.690 rs11657325 chr17:43242694 C/T cg10701640 chr17:43249399 NA 0.51 6.13 0.48 1.07e-8 Height; TGCT cis rs9486719 1.000 rs12201449 chr6:96959382 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs9527 0.545 rs7100369 chr10:104956218 C/A cg15744005 chr10:104629667 AS3MT -0.41 -4.78 -0.39 4.88e-6 Arsenic metabolism; TGCT cis rs12477438 0.798 rs2084987 chr2:99587885 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs950027 0.620 rs872192 chr15:45614502 A/G cg26924012 chr15:45694286 SPATA5L1 0.82 9.11 0.63 1.78e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs11874712 0.899 rs56075249 chr18:43670863 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.04e-7 Migraine - clinic-based; TGCT cis rs10875746 0.951 rs2286021 chr12:48528220 C/T cg20731937 chr12:48336164 NA 0.61 4.82 0.4 4.14e-6 Longevity (90 years and older); TGCT cis rs586688 0.625 rs654631 chr1:201658449 C/T cg07139329 chr1:201708558 NAV1 0.42 4.58 0.38 1.13e-5 Obesity-related traits; TGCT cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs7829975 0.514 rs2920983 chr8:8268063 G/C cg08975724 chr8:8085496 FLJ10661 0.58 5.14 0.42 1.04e-6 Mood instability; TGCT cis rs9818758 0.607 rs12715434 chr3:49295025 G/C cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs11122272 0.733 rs2749700 chr1:231522734 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.73 -7.29 -0.55 3.25e-11 Hemoglobin concentration; TGCT cis rs9894429 0.646 rs7406522 chr17:79615396 G/T cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs7829975 0.755 rs3789849 chr8:8687054 G/C cg06636001 chr8:8085503 FLJ10661 0.68 6.09 0.48 1.29e-8 Mood instability; TGCT cis rs8180040 1.000 rs811115 chr3:47322133 C/T cg27129171 chr3:47204927 SETD2 0.7 8.89 0.62 5.88e-15 Colorectal cancer; TGCT cis rs4862307 0.754 rs6846208 chr4:184991703 C/T cg06737308 chr4:185021514 ENPP6 0.41 5.9 0.47 3.31e-8 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg05665937 chr4:1216051 CTBP1 0.24 4.54 0.38 1.32e-5 Obesity-related traits; TGCT cis rs78487399 0.710 rs76857293 chr2:43591676 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1552244 0.938 rs56274701 chr3:10167790 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.61 -0.51 1.02e-9 Alzheimer's disease; TGCT trans rs62103177 0.810 rs62103188 chr18:77627661 G/A cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs11031096 0.727 rs2056853 chr11:4142172 C/T cg18678763 chr11:4115507 RRM1 -0.46 -5.73 -0.46 7.29e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9921222 0.585 rs7195617 chr16:376781 A/G cg10349874 chr16:420996 TMEM8A;MRPL28 0.29 5.16 0.42 9.56e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs6964587 0.967 rs7801058 chr7:91784381 C/T cg17063962 chr7:91808500 NA 0.95 8.85 0.62 7.26e-15 Breast cancer; TGCT cis rs8078723 0.966 rs57065891 chr17:38168227 C/T cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs9916302 0.706 rs439537 chr17:37734482 T/C cg03321784 chr17:37729644 NA 0.44 4.58 0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs2075371 0.637 rs13245165 chr7:133951492 A/T cg11752832 chr7:134001865 SLC35B4 0.66 5.52 0.44 1.93e-7 Mean platelet volume; TGCT cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs28386778 0.765 rs1974435 chr17:61994096 G/A cg06896619 chr17:61851486 DDX42;CCDC47 0.55 5.81 0.46 4.84e-8 Prudent dietary pattern; TGCT cis rs6938 0.534 rs11072512 chr15:75204026 C/T cg09165964 chr15:75287851 SCAMP5 0.54 5.07 0.41 1.39e-6 Breast cancer; TGCT cis rs17270561 1.000 rs79867288 chr6:25828416 A/G cg16482183 chr6:26056742 HIST1H1C 0.79 5.25 0.43 6.49e-7 Iron status biomarkers; TGCT cis rs317689 0.918 rs610192 chr12:69739941 T/C cg14784868 chr12:69753453 YEATS4 0.57 4.79 0.39 4.73e-6 Response to diuretic therapy; TGCT cis rs9926296 0.585 rs6500450 chr16:89858024 A/G cg21285383 chr16:89894308 SPIRE2 0.43 6.69 0.52 6.81e-10 Vitiligo; TGCT cis rs7208859 0.623 rs79607958 chr17:28934548 T/G cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3008870 0.583 rs11208985 chr1:67464666 G/A cg11518657 chr1:67396239 MIER1 -0.6 -4.76 -0.39 5.32e-6 Lymphocyte percentage of white cells; TGCT cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4246215 1 rs4246215 chr11:61564299 G/T cg01500311 chr11:61656094 FADS3 -0.3 -5.04 -0.41 1.64e-6 Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid);Platelet count;Inflammatory bowel disease;Trans fatty acid levels;Crohn's disease;Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid);Red blood cell fatty acid levels;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid); TGCT cis rs10892173 0.566 rs12364667 chr11:117675286 A/C cg21014159 chr11:117668035 DSCAML1 0.62 5.98 0.47 2.21e-8 Myopia; TGCT cis rs1538970 0.961 rs884962 chr1:45847981 G/A cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs4478858 0.735 rs6425737 chr1:31790288 T/C cg07478791 chr1:31886160 SERINC2 -0.51 -4.94 -0.41 2.47e-6 Alcohol dependence; TGCT cis rs12477438 0.798 rs6704766 chr2:99642818 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg08280861 chr8:58055591 NA 0.54 6.15 0.48 9.82e-9 Developmental language disorder (linguistic errors); TGCT cis rs1994135 0.715 rs11052742 chr12:33692290 A/C cg06521331 chr12:34319734 NA -0.31 -4.7 -0.39 6.83e-6 Resting heart rate; TGCT cis rs838147 0.537 rs503279 chr19:49209010 C/T cg13540341 chr19:49222985 MAMSTR 0.36 4.85 0.4 3.68e-6 Dietary macronutrient intake; TGCT cis rs12580194 0.593 rs55898514 chr12:55736238 G/A cg10672482 chr12:55725839 OR6C3 -0.51 -4.57 -0.38 1.17e-5 Cancer; TGCT cis rs832540 0.931 rs331499 chr5:56210923 C/T cg24531977 chr5:56204891 C5orf35 -0.5 -4.86 -0.4 3.48e-6 Coronary artery disease; TGCT cis rs7652177 1.000 rs7652177 chr3:171969077 C/G cg03587978 chr3:172165696 GHSR -0.28 -4.61 -0.38 9.77e-6 Height; TGCT cis rs595982 0.527 rs35087747 chr19:49377918 G/T cg15549821 chr19:49342101 PLEKHA4 -0.66 -7.99 -0.58 7.91e-13 Red cell distribution width; TGCT cis rs739496 0.579 rs7314870 chr12:112276464 T/C cg10833066 chr12:111807467 FAM109A 0.39 5.25 0.43 6.47e-7 Platelet count; TGCT cis rs9419702 0.568 rs9419635 chr10:133546164 C/T cg20568497 chr10:133558893 NA 0.47 5.21 0.42 7.48e-7 Survival in rectal cancer; TGCT cis rs514406 0.505 rs447581 chr1:53177098 T/C cg24675658 chr1:53192096 ZYG11B -0.78 -9.29 -0.64 6.63e-16 Monocyte count; TGCT cis rs1150668 0.796 rs213236 chr6:28324397 T/C cg19488431 chr6:28601329 NA 0.2 4.44 0.37 1.99e-5 Pubertal anthropometrics; TGCT cis rs453301 0.624 rs7014430 chr8:8827737 T/G cg06636001 chr8:8085503 FLJ10661 0.68 5.61 0.45 1.23e-7 Joint mobility (Beighton score); TGCT cis rs6456156 0.792 rs4710183 chr6:167514083 A/G cg07741184 chr6:167504864 NA -0.23 -4.66 -0.39 8.06e-6 Primary biliary cholangitis; TGCT cis rs6969780 0.915 rs10085570 chr7:27151188 C/T cg04321618 chr7:27170880 HOXA4 -0.5 -4.81 -0.4 4.35e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6089584 0.566 rs55881457 chr20:60608424 G/A cg06108461 chr20:60628389 TAF4 -0.44 -5.58 -0.45 1.44e-7 Body mass index; TGCT cis rs17681684 0.541 rs17810219 chr17:9764998 A/G cg15743799 chr17:9805578 RCVRN -0.27 -5.83 -0.46 4.61e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg02187348 chr16:89574699 SPG7 0.47 4.45 0.37 1.93e-5 Multiple myeloma (IgH translocation); TGCT cis rs66561647 0.929 rs67423398 chr8:128972220 C/T cg05480350 chr8:128972681 MIR1205;PVT1 0.21 4.5 0.37 1.52e-5 Hemoglobin concentration; TGCT cis rs314370 0.621 rs314312 chr7:100422642 G/C cg10426581 chr7:100472382 SRRT 0.72 7.41 0.55 1.69e-11 Resting heart rate; TGCT cis rs7432375 0.610 rs7621932 chr3:136517016 C/T cg15507776 chr3:136538369 TMEM22 0.55 5.64 0.45 1.1e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9534288 0.702 rs7331472 chr13:46644173 C/T cg15192986 chr13:46630673 CPB2 -0.53 -6.57 -0.51 1.28e-9 Blood protein levels; TGCT cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg18305652 chr10:134549665 INPP5A -0.33 -5.67 -0.45 9.3e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs10953454 1.000 rs10953454 chr7:104503813 G/A cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs4285028 0.747 rs9817818 chr3:121466826 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs2836633 0.929 rs2836610 chr21:40044502 C/T cg05519781 chr21:40033154 ERG 0.68 6.68 0.51 7.2e-10 Coronary artery disease; TGCT cis rs62169186 0.655 rs13383608 chr2:145093066 G/A cg15345847 chr2:145146928 ZEB2 -0.67 -4.54 -0.38 1.33e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9467711 0.591 rs3752417 chr6:26045905 G/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.6 -4.66 -0.39 7.95e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12220238 1.000 rs11000902 chr10:75920483 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.83 5.66 0.45 9.98e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs317689 0.684 rs315125 chr12:69758884 C/T cg11871910 chr12:69753446 YEATS4 0.55 4.72 0.39 6.38e-6 Response to diuretic therapy; TGCT cis rs875971 1.000 rs2077593 chr7:65892530 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs2486288 0.656 rs2413768 chr15:45561984 A/G cg26924012 chr15:45694286 SPATA5L1 -0.74 -7.37 -0.55 2.13e-11 Glomerular filtration rate; TGCT cis rs2439831 0.850 rs694985 chr15:43813387 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.58 0.45 1.46e-7 Lung cancer in ever smokers; TGCT cis rs4727027 0.901 rs1137432 chr7:148801658 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.68 0.39 7.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2204008 0.604 rs2320521 chr12:38253789 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.67 0.39 7.69e-6 Bladder cancer; TGCT cis rs1062177 0.774 rs2964574 chr5:151155711 G/A cg00977110 chr5:151150581 G3BP1 0.4 4.62 0.38 9.33e-6 Preschool internalizing problems; TGCT cis rs35883536 0.740 rs4604711 chr1:101089492 A/C cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.22e-5 Monocyte count; TGCT cis rs28595532 0.920 rs114333298 chr4:119765305 C/A cg14228332 chr4:119757509 SEC24D 1.28 6.65 0.51 8.36e-10 Cannabis dependence symptom count; TGCT cis rs6952808 1.000 rs59248873 chr7:1888185 A/G cg22963979 chr7:1858916 MAD1L1 -0.32 -4.95 -0.41 2.39e-6 Bipolar disorder and schizophrenia; TGCT cis rs2718812 0.607 rs12497433 chr3:133388584 C/G cg16414030 chr3:133502952 NA -0.4 -5.3 -0.43 5.16e-7 Iron status biomarkers; TGCT cis rs6964587 1.000 rs6951972 chr7:91689446 T/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs7659604 0.539 rs7699776 chr4:122753885 A/G cg06713675 chr4:122721982 EXOSC9 -0.68 -9.21 -0.64 1.05e-15 Type 2 diabetes; TGCT cis rs2836974 0.644 rs4818017 chr21:40690561 G/T cg11890956 chr21:40555474 PSMG1 -0.75 -6.81 -0.52 3.82e-10 Cognitive function; TGCT cis rs4727027 0.754 rs11764892 chr7:148858916 G/A cg23583168 chr7:148888333 NA -0.72 -8.22 -0.59 2.36e-13 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6714710 0.603 rs58546246 chr2:98521823 C/A cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs17102423 0.826 rs10873182 chr14:65605408 C/T cg11161011 chr14:65562177 MAX -0.47 -6.33 -0.49 4.15e-9 Obesity-related traits; TGCT cis rs131777 0.575 rs963980 chr22:51022117 C/A cg25309564 chr22:51001381 C22orf41 0.55 5.22 0.42 7.17e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs12142240 0.698 rs112068407 chr1:46822291 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs59197085 0.636 rs754920 chr7:128468412 A/G cg00260937 chr7:128520193 KCP -0.45 -4.66 -0.39 8.04e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs875971 0.895 rs12698520 chr7:65918707 C/A cg18876405 chr7:65276391 NA 0.31 4.79 0.39 4.74e-6 Aortic root size; TGCT cis rs10986311 0.802 rs7045589 chr9:127110354 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.97 0.41 2.19e-6 Vitiligo; TGCT cis rs2013441 1.000 rs2703792 chr17:20166950 G/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.56 -0.38 1.22e-5 Obesity-related traits; TGCT cis rs2251381 0.750 rs2776250 chr21:30528094 T/G cg24692254 chr21:30365293 RNF160 0.74 7.03 0.53 1.23e-10 Selective IgA deficiency; TGCT cis rs7552404 0.961 rs1767458 chr1:76219155 A/G cg22875332 chr1:76189707 ACADM 0.69 8.32 0.6 1.32e-13 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9467773 0.526 rs12199613 chr6:26367218 C/T cg05738196 chr6:26577821 NA -0.63 -6.61 -0.51 1.01e-9 Intelligence (multi-trait analysis); TGCT cis rs644799 0.965 rs3016295 chr11:95554311 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs17331151 0.573 rs11718060 chr3:52875546 G/A cg15956490 chr3:53032818 SFMBT1 0.46 5.51 0.44 2.02e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg10047753 chr17:41438598 NA 0.91 8.44 0.6 6.86e-14 Menopause (age at onset); TGCT cis rs12472274 0.941 rs4663861 chr2:239105203 C/T cg17459225 chr2:239074497 NA 0.33 4.84 0.4 3.79e-6 Phospholipid levels (plasma); TGCT cis rs2370759 1.000 rs11008865 chr10:32574842 C/T cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs6918586 0.658 rs13161 chr6:26114702 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.09e-9 Schizophrenia; TGCT cis rs7666738 0.752 rs62318905 chr4:99036103 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9325144 0.647 rs4616077 chr12:39092364 T/C cg26384229 chr12:38710491 ALG10B -0.55 -5.16 -0.42 9.52e-7 Morning vs. evening chronotype; TGCT cis rs6733011 0.628 rs6542838 chr2:99452458 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -4.81 -0.4 4.31e-6 Bipolar disorder; TGCT cis rs7674212 0.556 rs223401 chr4:103738972 T/C cg16532752 chr4:104119610 CENPE -0.61 -5.39 -0.44 3.41e-7 Type 2 diabetes; TGCT cis rs12200560 0.505 rs2387378 chr6:97077504 C/A cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg11494091 chr17:61959527 GH2 0.43 7.44 0.56 1.49e-11 Height; TGCT cis rs13242816 1.000 rs4292624 chr7:116102724 A/C cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT cis rs6570726 0.935 rs451349 chr6:145820894 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs62064224 0.533 rs11657826 chr17:30790386 T/A cg25809561 chr17:30822961 MYO1D 0.28 4.96 0.41 2.29e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs17484966 chr4:99014432 T/C cg05340658 chr4:99064831 C4orf37 0.47 5.33 0.43 4.51e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2562456 0.833 rs2562507 chr19:21726337 C/T cg25650185 chr19:21324782 ZNF431 0.59 5.28 0.43 5.71e-7 Pain; TGCT cis rs28374715 0.662 rs691906 chr15:41474636 T/A cg18705301 chr15:41695430 NDUFAF1 0.74 11.02 0.7 4.25e-20 Ulcerative colitis; TGCT cis rs2456568 0.803 rs10831141 chr11:93640728 C/T cg26875233 chr11:93583750 C11orf90 -0.49 -6.36 -0.5 3.47e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs12711979 0.729 rs6714956 chr2:3820454 T/C cg17052675 chr2:3827356 NA -0.4 -7.79 -0.57 2.27e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs9926296 0.632 rs1800286 chr16:89869761 T/C cg26513180 chr16:89883248 FANCA 0.76 7.1 0.54 8.68e-11 Vitiligo; TGCT cis rs1055129 0.560 rs2666003 chr17:73942976 G/A cg10935138 chr17:73851978 WBP2 0.55 4.87 0.4 3.35e-6 White matter hyperintensity burden; TGCT cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.54 -0.51 1.42e-9 Alzheimer's disease; TGCT cis rs12983728 0.831 rs34503352 chr19:58651296 G/A cg07378217 chr19:58662286 ZNF329 -0.82 -4.65 -0.39 8.28e-6 Cholesterol, total; TGCT cis rs2066819 1.000 rs2020854 chr12:56743367 T/C cg26714650 chr12:56694279 CS -1.44 -7.53 -0.56 8.91e-12 Psoriasis vulgaris; TGCT cis rs644799 1.000 rs644799 chr11:95564259 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.3 0.6 1.51e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9811920 0.715 rs1017967 chr3:99905803 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.38 -4.47 -0.37 1.71e-5 Axial length; TGCT cis rs7617773 0.963 rs6800730 chr3:48174210 C/T cg11946769 chr3:48343235 NME6 0.58 5.21 0.42 7.54e-7 Coronary artery disease; TGCT cis rs6840360 0.615 rs1561916 chr4:152479234 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs1865760 1.000 rs3752421 chr6:25918688 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.11 0.48 1.17e-8 Height; TGCT cis rs2197308 0.565 rs4123923 chr12:37857684 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.64 0.57 5e-12 Morning vs. evening chronotype; TGCT cis rs938554 0.657 rs7660895 chr4:9985445 A/G cg11266682 chr4:10021025 SLC2A9 0.45 4.46 0.37 1.81e-5 Blood metabolite levels; TGCT cis rs11098499 0.780 rs7692994 chr4:120427489 C/A cg09307838 chr4:120376055 NA 0.62 6.07 0.48 1.46e-8 Corneal astigmatism; TGCT cis rs7824557 0.628 rs7841394 chr8:11185671 G/T cg21775007 chr8:11205619 TDH 0.63 6.14 0.48 1.02e-8 Retinal vascular caliber; TGCT cis rs12048904 0.541 rs6699536 chr1:101276544 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.71 5.7 0.46 8.15e-8 Multiple sclerosis; TGCT cis rs71017072 1 rs71017072 chr7:19794295 G/GA cg05791153 chr7:19748676 TWISTNB 0.72 4.56 0.38 1.21e-5 Rubella; TGCT cis rs7072216 0.763 rs7923729 chr10:100169465 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs6964587 1.000 rs12533199 chr7:91757393 C/T cg17063962 chr7:91808500 NA 0.89 9.51 0.65 1.95e-16 Breast cancer; TGCT cis rs2404602 0.598 rs11634019 chr15:76634680 A/G cg22467129 chr15:76604101 ETFA 0.47 4.71 0.39 6.44e-6 Blood metabolite levels; TGCT cis rs6840360 0.615 rs4696266 chr4:152463421 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs7833790 0.724 rs1054078 chr8:82712153 A/G cg23324259 chr8:82754387 SNX16 -0.61 -4.71 -0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs250677 0.958 rs43147 chr5:148417103 C/G cg18129178 chr5:148520854 ABLIM3 0.4 5.57 0.45 1.5e-7 Breast cancer; TGCT cis rs6138458 1.000 rs7268095 chr20:24972333 C/T cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs4819052 0.580 rs419322 chr21:46551702 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.59 4.49 0.37 1.63e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT trans rs797680 0.856 rs6682670 chr1:93649732 A/G cg27528825 chr2:159282178 CCDC148 -0.35 -6.82 -0.52 3.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg20849893 chr7:64541193 NA -0.44 -4.62 -0.38 9.47e-6 Calcium levels; TGCT trans rs877282 0.947 rs4133015 chr10:774131 T/C cg22713356 chr15:30763199 NA 1.11 9.86 0.66 2.79e-17 Uric acid levels; TGCT cis rs13242816 1.000 rs66985071 chr7:116130433 C/T cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT cis rs4665809 1.000 rs6704930 chr2:26325705 G/A cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs2562456 0.917 rs10420016 chr19:21688602 C/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg00684032 chr4:1343700 KIAA1530 0.23 5.01 0.41 1.79e-6 Obesity-related traits; TGCT cis rs9534288 0.797 rs4294711 chr13:46575557 C/T cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg08736216 chr1:53307985 ZYG11A -0.28 -5.73 -0.46 7.33e-8 Monocyte count; TGCT cis rs904251 0.772 rs2776906 chr6:37431757 A/G cg25019722 chr6:37503610 NA -0.45 -5.33 -0.43 4.42e-7 Cognitive performance; TGCT cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs2535633 0.631 rs2336670 chr3:52998504 T/G cg10802521 chr3:52805072 NEK4 0.56 5.92 0.47 2.9e-8 Body mass index; TGCT cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg01448562 chr3:133502909 NA -0.28 -5.27 -0.43 5.8e-7 Iron status biomarkers; TGCT cis rs11696501 0.637 rs3746596 chr20:44312028 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.66 -0.39 7.97e-6 Brain structure; TGCT cis rs7412746 0.658 rs10305704 chr1:150804429 A/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.13 0.42 1.1e-6 Melanoma; TGCT cis rs2836950 0.545 rs2836922 chr21:40516308 C/T cg11890956 chr21:40555474 PSMG1 -0.72 -7.21 -0.54 4.91e-11 Menarche (age at onset); TGCT cis rs3087591 1.000 rs3087591 chr17:29630970 A/G cg24425628 chr17:29625626 OMG;NF1 -0.43 -6.35 -0.5 3.73e-9 Hip circumference; TGCT cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg20637647 chr7:64974828 NA 0.93 5.2 0.42 8.11e-7 Diabetic kidney disease; TGCT cis rs9581857 0.547 rs9579094 chr13:28081495 G/A cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2204008 0.744 rs12099650 chr12:38317140 C/G cg26384229 chr12:38710491 ALG10B 0.79 6.97 0.53 1.67e-10 Bladder cancer; TGCT cis rs2948294 0.566 rs13261997 chr8:8112295 C/T cg06636001 chr8:8085503 FLJ10661 0.84 7.05 0.53 1.13e-10 Red cell distribution width; TGCT cis rs72945132 0.882 rs7114200 chr11:70186099 C/A cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs1862618 0.671 rs2591955 chr5:56244948 C/T cg20203395 chr5:56204925 C5orf35 0.53 4.89 0.4 3.03e-6 Initial pursuit acceleration; TGCT cis rs1023500 0.505 rs134888 chr22:42674281 C/T cg15557168 chr22:42548783 NA -0.21 -4.84 -0.4 3.82e-6 Schizophrenia; TGCT cis rs7635838 1.000 rs7635838 chr3:11412604 A/G cg00170343 chr3:11313890 ATG7 0.57 5.5 0.44 2.07e-7 HDL cholesterol; TGCT cis rs9649213 0.533 rs1541409 chr7:98027580 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.95 -8.89 -0.62 5.83e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs6141600 0.627 rs2746100 chr20:34686075 A/C cg09179691 chr20:35094251 DLGAP4 0.19 4.58 0.38 1.1e-5 Height;Hip circumference; TGCT cis rs7666738 0.830 rs13147195 chr4:98893334 G/T cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.81e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7917772 0.619 rs2251772 chr10:104470918 T/C cg05855489 chr10:104503620 C10orf26 -0.63 -4.94 -0.41 2.52e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3772130 0.583 rs6767409 chr3:121564989 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.58 5.35 0.43 4.05e-7 Cognitive performance; TGCT cis rs6750047 0.691 rs336032 chr2:38264788 T/C cg07380506 chr2:38303506 CYP1B1 -0.55 -4.86 -0.4 3.5e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9486719 0.948 rs11152953 chr6:96894305 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7666738 0.791 rs11097601 chr4:98960103 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2594989 1.000 rs346081 chr3:11329085 A/G cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.47 0.56 1.26e-11 Platelet count; TGCT cis rs2050392 0.931 rs2265187 chr10:30690844 C/T cg18806716 chr10:30721971 MAP3K8 -0.44 -5.17 -0.42 9.28e-7 Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs7657497 chr4:99044028 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2688608 0.592 rs10824032 chr10:75528130 G/A cg15838173 chr10:75533400 FUT11 -0.3 -4.9 -0.4 2.89e-6 Inflammatory bowel disease; TGCT cis rs12541335 0.615 rs4872464 chr8:22153381 G/A cg26039829 chr8:22132926 PIWIL2 0.26 4.73 0.39 5.97e-6 Hypertriglyceridemia; TGCT cis rs17376456 0.877 rs12153788 chr5:93405437 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs12188164 1.000 rs72717412 chr5:429381 C/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.76 -0.39 5.27e-6 Cystic fibrosis severity; TGCT cis rs3845702 0.736 rs9288045 chr2:180814194 G/A cg01881094 chr2:180872142 CWC22 -1.05 -6.78 -0.52 4.27e-10 Schizophrenia; TGCT cis rs2439831 1.000 rs9920763 chr15:43760508 T/G cg02155558 chr15:43621948 ADAL;LCMT2 1.03 6.79 0.52 4.19e-10 Lung cancer in ever smokers; TGCT cis rs858239 0.932 rs1728313 chr7:23271031 A/C cg05602783 chr7:23145260 KLHL7 -0.64 -5.41 -0.44 3.17e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs11874712 0.527 rs9965812 chr18:43702733 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 -0.48 -4.68 -0.39 7.33e-6 Migraine - clinic-based; TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs12681287 0.640 rs13280468 chr8:87338452 C/T cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs8072100 1.000 rs8065669 chr17:45724996 G/A cg08085267 chr17:45401833 C17orf57 -0.47 -5.13 -0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs597539 0.652 rs478647 chr11:68700424 C/T cg04772025 chr11:68637568 NA 0.6 6.75 0.52 5.08e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs763121 0.853 rs4820345 chr22:39091151 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.45 0.56 1.41e-11 Menopause (age at onset); TGCT cis rs7666738 0.515 rs13142498 chr4:98792443 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.73 0.46 7.24e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7926906 0.875 rs2213084 chr11:90518158 G/A cg26138821 chr11:89956704 CHORDC1 -0.51 -5.52 -0.44 1.9e-7 Intelligence (multi-trait analysis); TGCT cis rs9393692 0.645 rs4145910 chr6:26313305 T/C cg00631329 chr6:26305371 NA -0.46 -6.91 -0.53 2.23e-10 Educational attainment; TGCT cis rs12142240 0.698 rs45517837 chr1:46859225 A/G cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT trans rs2727020 0.576 rs1814175 chr11:49559172 T/C cg03929089 chr4:120376271 NA -0.66 -7.6 -0.56 6.24e-12 Coronary artery disease; TGCT trans rs1814175 0.817 rs10769613 chr11:49769692 G/A cg15704280 chr7:45808275 SEPT13 -0.69 -8.05 -0.59 5.61e-13 Height; TGCT cis rs9486719 0.843 rs2472876 chr6:96845723 A/G cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs1371867 0.846 rs1613453 chr8:101244215 G/T cg00191853 chr8:101177733 SPAG1 0.22 4.51 0.38 1.48e-5 Atrioventricular conduction; TGCT cis rs425277 1.000 rs436045 chr1:2071556 A/G cg03732007 chr1:2071316 PRKCZ -0.26 -5.25 -0.43 6.29e-7 Height; TGCT trans rs11722228 0.522 rs12503195 chr4:10082772 T/C cg26043149 chr18:55253948 FECH 0.82 8.42 0.6 7.82e-14 Gout;Urate levels;Serum uric acid levels; TGCT cis rs7772486 0.875 rs2474356 chr6:146296798 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.66 0.66 8.33e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769707 0.604 rs1018814 chr22:50036900 T/C cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 4.99e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs12042938 0.600 rs823163 chr1:231771108 A/G cg04892437 chr1:231737901 TSNAX-DISC1 0.46 4.81 0.4 4.38e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs617219 0.698 rs7379187 chr5:78521354 T/C cg23514016 chr5:78407564 BHMT 0.34 5.25 0.43 6.28e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6952808 0.825 rs4236277 chr7:1942270 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.53 -0.45 1.78e-7 Bipolar disorder and schizophrenia; TGCT cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg22920501 chr2:26401640 FAM59B -0.78 -6.28 -0.49 5.18e-9 Gut microbiome composition (summer); TGCT cis rs4680 0.737 rs6269 chr22:19949952 A/G cg23601416 chr22:19950040 COMT -0.39 -5.07 -0.41 1.44e-6 Blood metabolite levels; TGCT cis rs295140 0.605 rs159321 chr2:201184713 C/T cg23649088 chr2:200775458 C2orf69 -0.27 -4.5 -0.37 1.55e-5 QT interval; TGCT cis rs9911578 0.902 rs12948746 chr17:57071892 A/G cg05425664 chr17:57184151 TRIM37 -0.67 -6.86 -0.52 2.88e-10 Intelligence (multi-trait analysis); TGCT cis rs7809950 0.678 rs79902674 chr7:106866498 A/C cg23024343 chr7:107201750 COG5 -0.43 -5.91 -0.47 3.13e-8 Coronary artery disease; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg12419862 chr22:24373484 LOC391322 -0.83 -9.3 -0.64 6.27e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs72945132 0.825 rs947811 chr11:70209142 A/T cg00319359 chr11:70116639 PPFIA1 0.98 7.13 0.54 7.33e-11 Coronary artery disease; TGCT cis rs6964587 0.967 rs2299235 chr7:91627500 C/T cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6540559 0.673 rs1073150 chr1:210017083 G/A cg22029157 chr1:209979665 IRF6 0.68 4.88 0.4 3.22e-6 Cleft lip with or without cleft palate; TGCT cis rs12540874 0.895 rs4245556 chr7:50661661 C/T cg18232548 chr7:50535776 DDC -0.31 -5.27 -0.43 5.96e-7 Systemic sclerosis; TGCT cis rs7917772 0.582 rs10786698 chr10:104378750 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg13695892 chr22:41940480 POLR3H 0.78 7.58 0.56 7.01e-12 Vitiligo; TGCT cis rs739496 0.579 rs11066051 chr12:112301760 G/C cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs13191362 1.000 rs36107456 chr6:162997399 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11190604 1.000 rs2495732 chr10:102357780 T/C cg23241863 chr10:102295624 HIF1AN 0.69 4.93 0.4 2.58e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9674544 0.757 rs9896443 chr17:47125982 A/G cg20966754 chr17:47091339 IGF2BP1 -0.44 -5.43 -0.44 2.91e-7 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs13082711 0.522 rs480646 chr3:27327143 C/T cg02860705 chr3:27208620 NA 0.34 5.66 0.45 9.82e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs1371867 0.875 rs1788168 chr8:101324960 G/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs6671200 0.573 rs3738171 chr1:95699594 A/G cg26537280 chr1:95699037 RWDD3 -0.54 -4.94 -0.41 2.42e-6 Stearic acid (18:0) levels; TGCT cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg12310025 chr6:25882481 NA -0.69 -7.5 -0.56 1.08e-11 Blood metabolite levels; TGCT cis rs3733585 0.699 rs6449171 chr4:9965998 C/T cg00071950 chr4:10020882 SLC2A9 0.54 6.48 0.5 1.97e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9486715 0.867 rs9384628 chr6:96960232 T/C cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs2456568 0.741 rs10831137 chr11:93636912 C/T cg14065697 chr11:93583672 C11orf90 -0.38 -4.74 -0.39 5.69e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs12532214 0.690 rs6971710 chr7:3140173 G/A cg19214707 chr7:3157722 NA -0.38 -4.57 -0.38 1.17e-5 Itch intensity from mosquito bite; TGCT cis rs427394 0.659 rs274674 chr5:6755460 C/T cg10857441 chr5:6722123 POLS -0.29 -6.12 -0.48 1.16e-8 Menopause (age at onset); TGCT cis rs7666738 0.830 rs3846445 chr4:99032939 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10927875 0.722 rs6696912 chr1:16338474 T/C cg21385522 chr1:16154831 NA 0.6 6.38 0.5 3.14e-9 Dilated cardiomyopathy; TGCT cis rs3806843 0.576 rs246030 chr5:140333154 C/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9291683 0.588 rs3756237 chr4:10013378 G/A cg00071950 chr4:10020882 SLC2A9 0.76 10.38 0.68 1.55e-18 Bone mineral density; TGCT cis rs2840044 1.000 rs11656138 chr17:33910218 T/C cg05299278 chr17:33885742 SLFN14 -0.23 -5.05 -0.41 1.53e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs68170813 0.559 rs78553765 chr7:106930787 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs644799 0.526 rs542509 chr11:95641602 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.49 4.97 0.41 2.19e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7949030 0.523 rs12223627 chr11:62368557 G/C cg13298116 chr11:62369859 EML3;MTA2 0.6 7.25 0.55 3.98e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT trans rs1496653 0.557 rs13087563 chr3:23322626 A/G cg02770683 chr12:57597238 LRP1 0.36 6.66 0.51 8.06e-10 Type 2 diabetes; TGCT cis rs8017423 0.647 rs12882973 chr14:90820502 G/A cg04374321 chr14:90722782 PSMC1 -0.56 -5.62 -0.45 1.19e-7 Mortality in heart failure; TGCT cis rs875971 1.000 rs4717292 chr7:65895598 G/A cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs3784262 0.935 rs4646563 chr15:58353335 T/C cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.84 -0.58 1.81e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs35883536 0.647 rs10875312 chr1:101042320 G/C cg10298815 chr1:101004474 GPR88 -0.25 -4.73 -0.39 6.03e-6 Monocyte count; TGCT cis rs7584330 0.910 rs6757376 chr2:238400036 G/C cg08992911 chr2:238395768 MLPH 0.58 4.51 0.38 1.49e-5 Prostate cancer; TGCT cis rs116095464 0.558 rs56043030 chr5:220917 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs2549003 1.000 rs7701588 chr5:131819970 T/C cg21138405 chr5:131827807 IRF1 0.19 4.79 0.4 4.64e-6 Asthma (sex interaction); TGCT cis rs4824093 0.541 rs8142132 chr22:50211294 C/T cg03660710 chr22:50631079 TRABD 0.36 4.49 0.37 1.59e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9302065 0.565 rs2993584 chr13:95961678 C/A cg24476569 chr13:95954382 ABCC4 -0.54 -8.26 -0.6 1.9e-13 Blood metabolite levels; TGCT cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg10295955 chr4:187884368 NA -1.0 -14.26 -0.79 6.69e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs6964587 0.900 rs7783674 chr7:91784212 T/A cg17063962 chr7:91808500 NA 0.91 9.83 0.66 3.33e-17 Breast cancer; TGCT cis rs10791097 0.678 rs10894272 chr11:130731081 A/G cg14779329 chr11:130786720 SNX19 0.27 4.64 0.38 8.6e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs634534 0.561 rs655744 chr11:65776585 G/T cg02427764 chr11:65769310 BANF1;EIF1AD -0.62 -6.11 -0.48 1.2e-8 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs4654899 1.000 rs6683542 chr1:21369610 T/C cg01072550 chr1:21505969 NA -0.49 -7.87 -0.58 1.47e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2180341 0.618 rs6683 chr6:127610021 G/A cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs34526934 0.608 rs7591820 chr2:177028144 G/T cg00278547 chr2:177037212 HOXD3 -0.4 -4.98 -0.41 2.09e-6 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs35306767 0.715 rs17293580 chr10:1034895 T/C cg20503657 chr10:835505 NA 0.64 7.06 0.54 1.04e-10 Eosinophil percentage of granulocytes; TGCT cis rs17473412 1.000 rs17473342 chr5:122697009 C/T cg15125798 chr5:122621645 NA 0.55 5.09 0.42 1.28e-6 Total body bone mineral density; TGCT cis rs12142240 0.698 rs17361791 chr1:46812519 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.79 -0.4 4.68e-6 Menopause (age at onset); TGCT cis rs1460583 0.961 rs1460582 chr8:106108281 C/T cg13963735 chr8:106810858 ZFPM2 0.27 4.44 0.37 1.98e-5 Schizophrenia; TGCT cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg09222892 chr1:25734099 RHCE -0.44 -7.09 -0.54 9.15e-11 Erythrocyte sedimentation rate; TGCT cis rs6426551 1.000 rs6426551 chr1:226542049 A/G cg18564989 chr1:226411057 MIXL1 -0.49 -4.95 -0.41 2.4e-6 Coronary artery disease; TGCT cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg10047753 chr17:41438598 NA 0.94 9.11 0.63 1.81e-15 Menopause (age at onset); TGCT cis rs7095607 0.538 rs2255027 chr10:69920911 T/C cg18986048 chr10:69913749 MYPN 0.61 5.85 0.46 4.16e-8 Lung function (FVC); TGCT cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg17328964 chr8:145687451 CYHR1 0.48 6.95 0.53 1.84e-10 Age at first birth; TGCT cis rs4689592 0.523 rs6446565 chr4:7074027 A/G cg25660036 chr4:7070649 GRPEL1 -0.67 -5.89 -0.47 3.39e-8 Monocyte percentage of white cells; TGCT cis rs2130392 0.924 rs873687 chr4:185638853 G/A cg14471096 chr4:185570637 CCDC111;CASP3 -0.52 -4.91 -0.4 2.85e-6 Kawasaki disease; TGCT cis rs12497850 0.931 rs9311430 chr3:48845251 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs1371867 0.775 rs3020183 chr8:101233297 A/T cg06636551 chr8:101224915 SPAG1 0.53 7.24 0.54 4.19e-11 Atrioventricular conduction; TGCT cis rs11249608 0.548 rs7707587 chr5:178462590 G/C cg21905437 chr5:178450457 ZNF879 0.44 4.55 0.38 1.25e-5 Pubertal anthropometrics; TGCT cis rs854765 0.693 rs11657074 chr17:17770355 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.76 -7.95 -0.58 9.74e-13 Total body bone mineral density; TGCT trans rs1814175 0.803 rs11040451 chr11:49650639 C/T cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs7172809 0.573 rs1015813 chr15:77533274 C/T cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT cis rs7089973 0.584 rs4752322 chr10:116613258 A/C cg03647239 chr10:116582469 FAM160B1 0.59 5.61 0.45 1.26e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs704 0.790 rs708100 chr17:26688663 G/A cg10342447 chr17:26645325 TMEM97 -0.56 -5.44 -0.44 2.73e-7 Osteoprotegerin levels; TGCT cis rs7267979 0.932 rs6115200 chr20:25487377 G/T cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10858047 0.831 rs10776787 chr1:115210161 A/T cg12756093 chr1:115239321 AMPD1 0.46 5.05 0.41 1.55e-6 Autism; TGCT cis rs55883249 0.957 rs17362839 chr2:9754439 T/C cg23886495 chr2:9695866 ADAM17 0.79 4.66 0.39 8.09e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1670533 1.000 rs7660779 chr4:1075940 A/G cg20887711 chr4:1340912 KIAA1530 0.72 5.8 0.46 5.25e-8 Recombination rate (females); TGCT cis rs7772486 0.625 rs2050027 chr6:146116113 C/G cg23711669 chr6:146136114 FBXO30 -0.86 -9.74 -0.66 5.4e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10206020 0.885 rs6746052 chr2:1576811 T/C cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs769267 0.930 rs3752151 chr19:19616026 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.65 5.44 0.44 2.74e-7 Tonsillectomy; TGCT cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg10560079 chr2:191398806 TMEM194B 0.37 5.33 0.43 4.5e-7 Pulse pressure; TGCT cis rs17376456 0.825 rs10038831 chr5:93124115 C/T cg25358565 chr5:93447407 FAM172A 0.91 8.22 0.59 2.27e-13 Diabetic retinopathy; TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg03188948 chr7:1209495 NA 0.46 6.3 0.49 4.7e-9 Longevity;Endometriosis; TGCT cis rs9913156 0.576 rs2036656 chr17:4622071 C/G cg19197139 chr17:4613644 ARRB2 -0.59 -5.37 -0.43 3.82e-7 Lymphocyte counts; TGCT cis rs7731657 0.537 rs12332151 chr5:130344771 T/C cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg15659132 chr6:26577336 NA -0.56 -5.55 -0.45 1.62e-7 Schizophrenia; TGCT cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs7582180 0.638 rs7581011 chr2:100954659 A/G cg08017756 chr2:100939284 LONRF2 0.3 4.92 0.4 2.7e-6 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.798 rs6542848 chr2:99573732 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.58 -0.61 3.24e-14 Chronic sinus infection; TGCT cis rs1857353 1.000 rs116436237 chr1:75931742 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.7 -0.39 6.94e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs77633900 0.614 rs2468116 chr15:76870998 G/A cg21673338 chr15:77095150 SCAPER -0.5 -4.71 -0.39 6.49e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs3784262 0.967 rs11630835 chr15:58269462 C/T cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.74 -0.57 3.01e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9467711 0.606 rs34622023 chr6:26362119 A/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7726839 0.540 rs55929359 chr5:595956 C/G cg16624210 chr5:671434 TPPP 0.43 4.66 0.39 8.1e-6 Obesity-related traits; TGCT cis rs67478160 0.643 rs6575999 chr14:104250609 C/G cg26031613 chr14:104095156 KLC1 -0.63 -6.36 -0.5 3.46e-9 Schizophrenia; TGCT cis rs36051895 0.589 rs62543573 chr9:5201675 A/G cg02405213 chr9:5042618 JAK2 -0.72 -9.21 -0.64 1.05e-15 Pediatric autoimmune diseases; TGCT cis rs854572 0.600 rs705382 chr7:94955221 C/G cg21856205 chr7:94953877 PON1 -0.63 -7.31 -0.55 2.86e-11 Paraoxonase activity; TGCT cis rs7412746 0.611 rs4970984 chr1:150887377 T/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs10089 0.953 rs1432614 chr5:127416919 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.81 7.51 0.56 1e-11 Ileal carcinoids; TGCT trans rs61931739 0.500 rs11524949 chr12:34435551 C/T cg26384229 chr12:38710491 ALG10B 0.73 6.92 0.53 2.11e-10 Morning vs. evening chronotype; TGCT cis rs2455799 0.517 rs6442553 chr3:15927193 A/G cg12172478 chr3:16357591 RFTN1 -0.34 -4.98 -0.41 2.09e-6 Mean platelet volume; TGCT cis rs79349575 0.651 rs4378658 chr17:46993370 G/A cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg09904177 chr6:26538194 HMGN4 0.63 5.65 0.45 1.05e-7 Intelligence (multi-trait analysis); TGCT cis rs12421382 0.659 rs60143378 chr11:109385513 T/C cg16359550 chr11:109292809 C11orf87 0.43 4.79 0.39 4.73e-6 Schizophrenia; TGCT cis rs7100689 0.622 rs10736344 chr10:82133955 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg17554472 chr22:41940697 POLR3H -0.46 -4.72 -0.39 6.27e-6 Vitiligo; TGCT cis rs2019216 0.542 rs7217513 chr17:21933536 C/A cg22648282 chr17:21454238 C17orf51 -0.59 -5.89 -0.47 3.46e-8 Pelvic organ prolapse; TGCT cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg09436375 chr6:42928200 GNMT -0.4 -5.23 -0.42 7.13e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2486288 0.656 rs11632778 chr15:45551056 C/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg11890956 chr21:40555474 PSMG1 0.8 7.6 0.56 6.2e-12 Cognitive function; TGCT cis rs651907 0.514 rs12636046 chr3:101434448 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 10.45 0.68 1.02e-18 Colorectal cancer; TGCT cis rs28595532 0.920 rs116717907 chr4:119762568 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs1059312 0.772 rs11609637 chr12:129300202 T/G cg09035930 chr12:129282057 SLC15A4 0.56 10.49 0.69 8.05e-19 Systemic lupus erythematosus; TGCT cis rs589448 0.902 rs315131 chr12:69761839 T/G cg20891283 chr12:69753455 YEATS4 0.9 10.36 0.68 1.69e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs3087591 0.960 rs2953009 chr17:29498387 A/C cg24425628 chr17:29625626 OMG;NF1 0.45 6.95 0.53 1.84e-10 Hip circumference; TGCT cis rs10504229 0.871 rs10504227 chr8:58162005 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.19e-7 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs56389935 chr4:119683571 G/A cg21605333 chr4:119757512 SEC24D 1.4 7.38 0.55 1.97e-11 Cannabis dependence symptom count; TGCT cis rs2242116 0.900 rs4683300 chr3:46934292 C/A cg27129171 chr3:47204927 SETD2 0.61 6.15 0.48 9.79e-9 Birth weight; TGCT cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg11301795 chr4:187892539 NA -0.33 -5.11 -0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12497850 0.931 rs4072859 chr3:49032205 G/C cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.97e-6 Parkinson's disease; TGCT trans rs2727020 0.576 rs12293522 chr11:49558425 T/A cg15704280 chr7:45808275 SEPT13 -0.75 -8.8 -0.62 9.9e-15 Coronary artery disease; TGCT cis rs3806843 0.801 rs2531358 chr5:140117437 A/G cg19875535 chr5:140030758 IK -0.35 -5.92 -0.47 2.9e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs72945132 0.882 rs7123602 chr11:70181489 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg06640241 chr16:89574553 SPG7 0.77 8.65 0.61 2.25e-14 Multiple myeloma (IgH translocation); TGCT cis rs7412746 0.611 rs11204726 chr1:150743492 T/C cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs782590 0.967 rs1975484 chr2:55803167 T/A cg18811423 chr2:55921094 PNPT1 0.65 6.93 0.53 2.04e-10 Metabolic syndrome; TGCT cis rs2153535 0.580 rs2327056 chr6:8443305 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg02953382 chr22:24373134 LOC391322 -0.77 -7.98 -0.58 8.41e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9911578 0.839 rs7208505 chr17:57187729 C/T cg05425664 chr17:57184151 TRIM37 -0.65 -6.6 -0.51 1.09e-9 Intelligence (multi-trait analysis); TGCT cis rs66561647 0.518 rs4733806 chr8:128909539 C/T cg11792826 chr8:129160931 MIR1208 0.23 5.04 0.41 1.62e-6 Hemoglobin concentration; TGCT cis rs11252926 0.537 rs6560836 chr10:444997 C/T cg13477178 chr10:375248 DIP2C -0.24 -4.52 -0.38 1.45e-5 Psychosis in Alzheimer's disease; TGCT cis rs637571 0.522 rs28578718 chr11:65748400 C/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.67 6.57 0.51 1.27e-9 Eosinophil percentage of white cells; TGCT cis rs6748734 1.000 rs7604393 chr2:241825034 T/G cg04034577 chr2:241836375 C2orf54 -0.4 -6.32 -0.49 4.22e-9 Urinary metabolites; TGCT cis rs7552404 0.924 rs1313071 chr1:76195542 C/G cg10523679 chr1:76189770 ACADM 0.85 9.41 0.65 3.37e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs8064299 0.597 rs6501737 chr17:72780830 C/T cg25054828 chr17:72772726 NAT9;TMEM104 -0.83 -9.62 -0.65 1.08e-16 Monocyte count; TGCT cis rs1691799 0.867 rs1168333 chr12:66761377 G/A cg16791601 chr12:66731901 HELB -0.27 -5.66 -0.45 9.92e-8 White blood cell count (basophil); TGCT cis rs12681287 0.547 rs10087788 chr8:87544174 G/A cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT cis rs6671200 0.915 rs259334 chr1:95739701 C/T cg03123541 chr1:95699097 RWDD3 -1.0 -6.44 -0.5 2.43e-9 Stearic acid (18:0) levels; TGCT cis rs6565180 0.962 rs35480350 chr16:30366039 G/A cg17640201 chr16:30407289 ZNF48 -0.87 -8.21 -0.59 2.4e-13 Tonsillectomy; TGCT trans rs3790455 0.804 rs1109751 chr1:156439000 C/T cg16443977 chr5:115884994 SEMA6A -0.36 -6.65 -0.51 8.53e-10 Migraine; TGCT cis rs7772486 0.754 rs697055 chr6:146003790 C/G cg13319975 chr6:146136371 FBXO30 -0.55 -5.14 -0.42 1.03e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1062177 1.000 rs2964578 chr5:151147198 T/A cg12924095 chr5:151150029 G3BP1 0.35 5.04 0.41 1.6e-6 Preschool internalizing problems; TGCT cis rs765787 0.530 rs11636404 chr15:45535861 C/G cg24006582 chr15:45444508 DUOX1 -0.24 -5.29 -0.43 5.34e-7 Uric acid levels; TGCT cis rs453301 0.509 rs7000323 chr8:8792273 G/A cg06636001 chr8:8085503 FLJ10661 -0.6 -4.85 -0.4 3.56e-6 Joint mobility (Beighton score); TGCT cis rs61774743 0.714 rs2364543 chr1:41833089 T/G cg01193554 chr1:41846683 NA 0.41 4.91 0.4 2.84e-6 Intelligence (multi-trait analysis); TGCT cis rs12220238 0.915 rs10824164 chr10:76137032 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.88 5.86 0.47 3.87e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9611565 0.614 rs4822053 chr22:42212936 C/A cg06481639 chr22:41940642 POLR3H -0.55 -4.69 -0.39 6.98e-6 Vitiligo; TGCT cis rs7552404 0.921 rs10873685 chr1:76218818 A/C cg10523679 chr1:76189770 ACADM 0.92 9.67 0.66 8.16e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3751972 0.668 rs9903233 chr17:26216356 G/A cg02948944 chr17:26242737 NA 0.33 4.8 0.4 4.48e-6 Fractional exhaled nitric oxide (childhood); TGCT cis rs12497850 0.644 rs11928552 chr3:48739883 T/C cg06212747 chr3:49208901 KLHDC8B 0.62 5.7 0.46 8.17e-8 Parkinson's disease; TGCT cis rs12971120 0.947 rs4891559 chr18:72170397 C/T cg26446133 chr18:72167187 CNDP2 -0.4 -7.73 -0.57 3.15e-12 Refractive error; TGCT cis rs3806843 0.520 rs265312 chr5:140296272 T/G cg09824255 chr5:140014002 CD14 0.25 4.48 0.37 1.69e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs763121 0.853 rs1569716 chr22:38998519 C/A cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs3008870 1.000 rs2985821 chr1:67403787 G/A cg03991309 chr1:68237761 GNG12 0.27 4.55 0.38 1.26e-5 Lymphocyte percentage of white cells; TGCT cis rs6977940 0.818 rs73033466 chr7:2902617 G/C cg19731401 chr7:2775893 GNA12 0.37 4.44 0.37 1.94e-5 White matter integrity; TGCT cis rs1799949 0.929 rs799906 chr17:41278116 T/C cg05368731 chr17:41323189 NBR1 1.07 12.07 0.73 1.17e-22 Menopause (age at onset); TGCT cis rs1577917 0.958 rs1816937 chr6:86557251 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs3733585 0.648 rs7376155 chr4:9952588 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.65 -0.57 4.78e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs202629 1 rs202629 chr22:41849975 C/T cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Cannabis dependence symptom count; TGCT cis rs6921919 0.609 rs1005127 chr6:28367658 G/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg07167872 chr1:205819463 PM20D1 0.67 9.56 0.65 1.49e-16 Menarche (age at onset); TGCT cis rs28595532 0.841 rs116587722 chr4:119790517 T/C cg14228332 chr4:119757509 SEC24D 1.31 6.68 0.51 7.27e-10 Cannabis dependence symptom count; TGCT cis rs6754311 0.773 rs4988226 chr2:136610598 A/G cg07169764 chr2:136633963 MCM6 -0.62 -5.74 -0.46 7e-8 Mosquito bite size; TGCT cis rs7103648 0.669 rs12577383 chr11:47774238 C/T cg20307385 chr11:47447363 PSMC3 0.77 7.25 0.55 3.99e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg06481639 chr22:41940642 POLR3H 0.86 6.43 0.5 2.5e-9 Vitiligo; TGCT cis rs9677476 0.516 rs10169827 chr2:232049722 A/G cg07929768 chr2:232055508 NA 0.32 5.05 0.41 1.53e-6 Food antigen IgG levels; TGCT cis rs3096299 0.935 rs3102387 chr16:89432276 A/C cg02187348 chr16:89574699 SPG7 0.48 4.69 0.39 7.11e-6 Multiple myeloma (IgH translocation); TGCT cis rs4478858 0.735 rs7526095 chr1:31797581 C/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs9913156 0.789 rs72824966 chr17:4596679 T/C cg23387401 chr17:4582204 PELP1 0.31 4.68 0.39 7.44e-6 Lymphocyte counts; TGCT cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.41 2.55e-6 Obesity-related traits; TGCT cis rs13256369 1.000 rs4841016 chr8:8572561 C/T cg06671706 chr8:8559999 CLDN23 0.34 4.44 0.37 1.99e-5 Obesity-related traits; TGCT cis rs7248779 1.000 rs7248779 chr19:2403564 G/T cg22729335 chr19:2427816 TIMM13 -0.67 -6.83 -0.52 3.4e-10 Cortisol levels (saliva); TGCT cis rs1403694 1.000 rs2304451 chr3:186437661 G/C cg12454167 chr3:186435060 KNG1 0.43 7.53 0.56 9.3e-12 Blood protein levels; TGCT cis rs6700896 0.500 rs4655566 chr1:66088951 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7659604 0.539 rs72680779 chr4:122797263 C/T cg19748678 chr4:122722346 EXOSC9 0.85 8.39 0.6 9.24e-14 Type 2 diabetes; TGCT cis rs7666738 0.791 rs1559860 chr4:99024422 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7524258 0.868 rs6577428 chr1:7314655 C/T cg07173049 chr1:7289937 CAMTA1 -0.29 -4.83 -0.4 3.96e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg00149659 chr3:10157352 C3orf10 -0.89 -5.76 -0.46 6.17e-8 Alzheimer's disease; TGCT cis rs7937682 0.632 rs57414412 chr11:111769431 G/A cg09085632 chr11:111637200 PPP2R1B 0.83 7.15 0.54 6.45e-11 Primary sclerosing cholangitis; TGCT cis rs7246657 0.722 rs12974225 chr19:38240098 G/T cg03611452 chr19:38183253 ZNF781 -0.59 -4.94 -0.41 2.45e-6 Coronary artery calcification; TGCT cis rs2235642 0.928 rs2076435 chr16:1607574 C/T cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.74 -0.39 5.81e-6 Coronary artery disease; TGCT cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7949030 0.626 rs7124057 chr11:62334096 A/G cg11742103 chr11:62369870 EML3;MTA2 0.61 8.71 0.62 1.65e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7552404 0.765 rs211717 chr1:76106969 G/A cg22875332 chr1:76189707 ACADM -0.79 -9.72 -0.66 6.2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1046896 0.514 rs67735447 chr17:80823042 G/T cg03160526 chr17:80928410 B3GNTL1 0.33 4.46 0.37 1.8e-5 Glycated hemoglobin levels; TGCT cis rs854765 0.583 rs6502625 chr17:17848286 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.69 6.93 0.53 1.99e-10 Total body bone mineral density; TGCT cis rs6430585 0.640 rs6716070 chr2:136544651 G/T cg07169764 chr2:136633963 MCM6 -1.19 -11.11 -0.71 2.49e-20 Corneal structure; TGCT cis rs12762955 0.529 rs2387213 chr10:1051420 C/T cg20503657 chr10:835505 NA 0.41 5.24 0.43 6.54e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs9372253 0.678 rs6568644 chr6:110707820 C/T cg01119278 chr6:110721349 DDO -0.3 -4.54 -0.38 1.32e-5 Platelet distribution width; TGCT cis rs2046867 0.818 rs62249866 chr3:72878632 T/C cg25664220 chr3:72788482 NA -0.57 -6.33 -0.49 4.08e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1008375 1.000 rs4698634 chr4:17630192 A/C cg10189774 chr4:17578691 LAP3 -0.59 -5.13 -0.42 1.06e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2734839 0.537 rs11214603 chr11:113279922 G/A cg14159747 chr11:113255604 NA 0.37 4.75 0.39 5.46e-6 Information processing speed; TGCT cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg11301795 chr4:187892539 NA -0.33 -4.82 -0.4 4.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3213545 0.700 rs2260445 chr12:121468863 C/A cg15155738 chr12:121454335 C12orf43 0.47 4.64 0.38 8.71e-6 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs2836950 0.527 rs2836958 chr21:40623526 T/C cg11644478 chr21:40555479 PSMG1 -0.51 -4.77 -0.39 5.15e-6 Menarche (age at onset); TGCT cis rs8020441 0.541 rs72681652 chr14:51156155 C/T cg04730355 chr14:51134070 SAV1 1.23 9.65 0.66 8.78e-17 Cognitive performance; TGCT cis rs7439150 0.954 rs72679193 chr4:155470398 A/G cg22130008 chr4:155548532 NA -0.45 -5.5 -0.44 2.03e-7 Fibrinogen levels; TGCT cis rs72945132 0.638 rs627079 chr11:70165505 G/T cg00319359 chr11:70116639 PPFIA1 0.84 6.75 0.52 5.05e-10 Coronary artery disease; TGCT cis rs6545883 0.929 rs3732170 chr2:61749716 C/T cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs17376456 0.542 rs1453003 chr5:93151611 T/C cg25358565 chr5:93447407 FAM172A -0.76 -6.72 -0.52 5.94e-10 Diabetic retinopathy; TGCT cis rs13191362 1.000 rs28360546 chr6:163210973 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.93 5.86 0.47 3.91e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg09222892 chr1:25734099 RHCE -0.43 -7.0 -0.53 1.43e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs6674176 0.628 rs3791119 chr1:44431362 C/G cg13606994 chr1:44402422 ARTN -0.46 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9308731 1.000 rs6750599 chr2:111893869 A/T cg04202892 chr2:111875749 ACOXL -0.42 -4.45 -0.37 1.9e-5 Chronic lymphocytic leukemia; TGCT cis rs7959452 0.590 rs28778648 chr12:69771911 C/A cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs4478858 0.735 rs11583123 chr1:31751772 T/C cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs28735056 0.935 rs11662267 chr18:77641902 C/G cg20368463 chr18:77673604 PQLC1 -0.45 -5.58 -0.45 1.43e-7 Schizophrenia; TGCT cis rs1348850 0.567 rs1527401 chr2:178522104 C/T cg22681709 chr2:178499509 PDE11A -0.5 -6.33 -0.49 4.17e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9796 0.689 rs13329537 chr15:41449211 C/G cg18705301 chr15:41695430 NDUFAF1 0.54 7.13 0.54 7.14e-11 Menopause (age at onset); TGCT cis rs6674970 0.966 rs10788800 chr1:151104950 G/A cg00003202 chr1:151319512 RFX5 -0.51 -4.46 -0.37 1.84e-5 Childhood ear infection; TGCT cis rs514406 0.861 rs6588443 chr1:53250650 G/A cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs2832191 0.597 rs8127842 chr21:30516461 G/A cg24692254 chr21:30365293 RNF160 -0.62 -5.46 -0.44 2.44e-7 Dental caries; TGCT cis rs114540395 1.000 rs114540395 chr10:103479062 C/T cg03300883 chr10:102748874 C10orf2 0.44 4.87 0.4 3.32e-6 Schizophrenia; TGCT cis rs55704346 1.000 rs1032684 chr4:25198523 C/T cg26487582 chr4:25322200 ZCCHC4 0.18 4.57 0.38 1.18e-5 Tonsillectomy; TGCT cis rs780096 0.565 rs10169261 chr2:27727314 C/T cg12000995 chr2:27665139 KRTCAP3 -0.37 -4.5 -0.37 1.52e-5 Total body bone mineral density; TGCT cis rs11122272 0.525 rs61835222 chr1:231537917 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs10256972 0.647 rs10233430 chr7:1051664 T/C cg00431813 chr7:1051703 C7orf50 -0.26 -5.59 -0.45 1.35e-7 Longevity;Endometriosis; TGCT cis rs7917772 0.503 rs6584510 chr10:104299868 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4819052 0.851 rs7275468 chr21:46656499 C/A cg06618935 chr21:46677482 NA -0.34 -5.35 -0.43 4.13e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9443645 0.901 rs4706077 chr6:79548845 G/A cg05283184 chr6:79620031 NA -0.21 -4.77 -0.39 5.11e-6 Intelligence (multi-trait analysis); TGCT cis rs11690935 0.959 rs6738445 chr2:172599615 T/C cg13550731 chr2:172543902 DYNC1I2 1.21 13.23 0.77 1.87e-25 Schizophrenia; TGCT cis rs7211079 0.833 rs7220523 chr17:78127695 G/A cg09238746 chr17:78121135 EIF4A3 -0.73 -5.86 -0.47 3.98e-8 Myocardial infarction; TGCT cis rs79387448 0.638 rs7600961 chr2:103035455 G/A cg09003973 chr2:102972529 NA 1.27 9.82 0.66 3.37e-17 Gut microbiota (bacterial taxa); TGCT cis rs35146811 0.695 rs1618851 chr7:99810643 T/G cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs6840360 1.000 rs6823194 chr4:152604543 T/C cg17479576 chr4:152424074 FAM160A1 -0.44 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis); TGCT cis rs789859 1.000 rs789860 chr3:194405630 A/T cg21106136 chr3:194405973 FAM43A -0.36 -5.11 -0.42 1.21e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs11578119 1.000 rs10919426 chr1:170501746 C/G cg09767346 chr1:170501363 GORAB 0.65 5.17 0.42 9.21e-7 Male-pattern baldness; TGCT cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg26818010 chr10:134567672 INPP5A -0.37 -5.17 -0.42 9.23e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs4851251 1.000 rs4851251 chr2:100753490 C/T cg22139774 chr2:100720529 AFF3 0.4 5.42 0.44 2.98e-7 Educational attainment (years of education); TGCT cis rs7772486 0.764 rs7762562 chr6:146158994 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.99 0.41 2.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs34526934 0.608 rs34720456 chr2:177027292 G/A cg14324370 chr2:177042789 NA -0.9 -8.57 -0.61 3.41e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg09904177 chr6:26538194 HMGN4 0.68 6.36 0.5 3.55e-9 Intelligence (multi-trait analysis); TGCT cis rs5769707 0.568 rs2011097 chr22:50018069 A/G cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 4.95e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs66573146 0.803 rs59742225 chr4:6969942 C/T cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg12386194 chr3:101231763 SENP7 0.49 4.81 0.4 4.29e-6 Colorectal cancer; TGCT cis rs981844 0.712 rs3925717 chr4:154750917 C/G cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs1467026 0.719 rs17037220 chr3:12818103 A/G cg05775895 chr3:12838266 CAND2 0.79 7.85 0.58 1.67e-12 P wave duration; TGCT cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT cis rs877282 1.000 rs12763443 chr10:771941 G/A cg17470449 chr10:769945 NA 0.31 4.89 0.4 3.03e-6 Uric acid levels; TGCT cis rs12458462 0.851 rs2169249 chr18:77489649 G/A cg11879182 chr18:77439856 CTDP1 0.71 8.07 0.59 5.19e-13 Monocyte count; TGCT cis rs9393692 1.000 rs9393692 chr6:26276650 A/G cg13736514 chr6:26305472 NA -0.43 -6.32 -0.49 4.38e-9 Educational attainment; TGCT cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs8180040 0.726 rs7610636 chr3:47064436 A/C cg27129171 chr3:47204927 SETD2 -0.77 -10.59 -0.69 4.55e-19 Colorectal cancer; TGCT cis rs6964587 0.933 rs10271174 chr7:91785970 A/G cg22709100 chr7:91322751 NA 0.29 4.71 0.39 6.62e-6 Breast cancer; TGCT cis rs9326248 0.581 rs7120515 chr11:116991926 A/G cg01368799 chr11:117014884 PAFAH1B2 0.58 5.34 0.43 4.35e-7 Blood protein levels; TGCT cis rs926938 0.563 rs360661 chr1:115455280 G/A cg12756093 chr1:115239321 AMPD1 0.4 6.33 0.49 4.02e-9 Autism; TGCT cis rs919433 0.617 rs10931791 chr2:198573612 A/C cg00792783 chr2:198669748 PLCL1 -0.51 -4.83 -0.4 3.87e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs9910055 0.530 rs2269906 chr17:42294337 G/T cg19774624 chr17:42201019 HDAC5 0.68 7.51 0.56 1.02e-11 Total body bone mineral density; TGCT cis rs11676348 0.846 rs4674259 chr2:218991005 C/T cg00012203 chr2:219082015 ARPC2 -0.52 -4.94 -0.41 2.5e-6 Ulcerative colitis; TGCT cis rs617219 0.710 rs2166344 chr5:78534134 T/G cg09550809 chr5:78407562 BHMT 0.37 5.24 0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6840360 0.653 rs13136369 chr4:152731283 T/G cg22705602 chr4:152727874 NA 0.27 5.06 0.41 1.46e-6 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs2013441 0.965 rs7207611 chr17:20204516 C/T cg23224458 chr17:20280056 CCDC144C 0.41 4.88 0.4 3.25e-6 Obesity-related traits; TGCT cis rs2282802 0.685 rs10077671 chr5:139689505 C/T cg01081189 chr5:139537190 NA 0.27 4.93 0.4 2.55e-6 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs2327060 chr6:8447111 G/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs79387448 0.638 rs78123896 chr2:103075417 T/C cg09003973 chr2:102972529 NA 1.28 9.8 0.66 3.95e-17 Gut microbiota (bacterial taxa); TGCT cis rs986417 1.000 rs11158293 chr14:61109020 G/C cg27398547 chr14:60952738 C14orf39 1.56 8.73 0.62 1.45e-14 Gut microbiota (bacterial taxa); TGCT cis rs704 0.764 rs3093692 chr17:26670627 G/A cg10342447 chr17:26645325 TMEM97 -0.55 -5.2 -0.42 7.94e-7 Osteoprotegerin levels; TGCT cis rs8072100 0.905 rs9901869 chr17:45575206 G/A cg10024583 chr17:45772800 TBKBP1 0.43 4.47 0.37 1.74e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2469997 1.000 rs2470012 chr8:120360488 T/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs3093024 1.000 rs3093024 chr6:167532793 C/T cg07741184 chr6:167504864 NA 0.23 4.66 0.39 7.98e-6 Rheumatoid arthritis; TGCT cis rs11190604 0.767 rs4559620 chr10:102199935 C/T cg16005271 chr10:102321736 NA 0.47 4.66 0.39 8.14e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs933688 0.759 rs1423593 chr5:90752351 T/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 9.29 0.64 6.55e-16 Smoking behavior; TGCT cis rs12753569 0.934 rs10430051 chr1:76491628 T/G cg00791851 chr1:76518896 NA -0.4 -5.49 -0.44 2.2e-7 Personality dimensions; TGCT cis rs1891275 0.515 rs4244930 chr10:93466849 T/C cg07889827 chr10:93443413 NA -0.32 -6.75 -0.52 5.12e-10 Intelligence (multi-trait analysis); TGCT cis rs6831352 0.918 rs1042364 chr4:100045574 T/C cg12011299 chr4:100065546 ADH4 0.41 4.92 0.4 2.72e-6 Alcohol dependence; TGCT cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg22618164 chr12:122356400 WDR66 0.53 5.18 0.42 8.83e-7 Mean corpuscular volume; TGCT cis rs73058052 0.709 rs10416310 chr19:50079846 G/A cg14048834 chr19:49990801 RPL13AP5;RPL13A -0.52 -4.48 -0.37 1.66e-5 Fibrinogen levels; TGCT cis rs9611519 0.780 rs9611542 chr22:41677317 C/T cg03806693 chr22:41940476 POLR3H -0.81 -8.15 -0.59 3.41e-13 Neuroticism; TGCT cis rs3617 0.573 rs2336668 chr3:52919096 G/T cg11645453 chr3:52864694 ITIH4 -0.27 -5.17 -0.42 9.18e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1008375 1.000 rs1860597 chr4:17657650 C/T cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12220898 0.749 rs2377976 chr10:50479493 A/G cg12697796 chr10:49954016 WDFY4 0.52 4.81 0.4 4.3e-6 Inflammatory biomarkers; TGCT cis rs6866344 0.697 rs17184344 chr5:178129281 A/G cg10224037 chr5:178157518 ZNF354A 0.93 8.22 0.59 2.25e-13 Neutrophil percentage of white cells; TGCT cis rs8177253 0.511 rs9830001 chr3:133433470 A/G cg11941060 chr3:133502564 NA 0.23 4.66 0.39 7.97e-6 Iron status biomarkers; TGCT cis rs250677 0.652 rs36042 chr5:148439782 G/T cg23229984 chr5:148520753 ABLIM3 0.22 4.98 0.41 2.05e-6 Breast cancer; TGCT cis rs372883 0.648 rs368322 chr21:30717151 C/T cg24692254 chr21:30365293 RNF160 -0.52 -4.64 -0.38 8.89e-6 Pancreatic cancer; TGCT cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs751728 0.638 rs4713686 chr6:33787506 C/T cg13859433 chr6:33739653 LEMD2 -0.33 -5.53 -0.44 1.83e-7 Crohn's disease; TGCT cis rs6860806 0.507 rs2631364 chr5:131706914 C/G cg24060327 chr5:131705240 SLC22A5 0.78 8.46 0.61 6.22e-14 Breast cancer; TGCT cis rs950027 0.620 rs1145093 chr15:45649813 C/A cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs7572733 0.534 rs13026569 chr2:198783330 C/G cg00792783 chr2:198669748 PLCL1 -0.57 -5.14 -0.42 1.03e-6 Dermatomyositis; TGCT cis rs11673344 0.504 rs10402907 chr19:37603776 G/T cg08039142 chr19:36980659 ZNF566 0.51 4.72 0.39 6.29e-6 Obesity-related traits; TGCT cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg03806693 chr22:41940476 POLR3H 1.08 11.99 0.73 1.84e-22 Vitiligo; TGCT cis rs9814567 0.806 rs2293293 chr3:134322742 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.74 -6.86 -0.52 2.97e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6545883 0.929 rs778155 chr2:61647901 A/G cg15711740 chr2:61764176 XPO1 0.58 5.2 0.42 7.96e-7 Tuberculosis; TGCT cis rs9581857 0.547 rs9581876 chr13:28101113 T/C cg22138327 chr13:27999177 GTF3A 0.72 4.75 0.39 5.45e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6893807 1.000 rs3814424 chr5:87968953 C/T cg24804195 chr5:87968844 LOC645323 0.73 5.29 0.43 5.39e-7 Body mass index; TGCT cis rs8179 0.645 rs11764331 chr7:92282624 C/T cg15732164 chr7:92237376 CDK6 -0.29 -5.06 -0.41 1.46e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT trans rs208520 0.955 rs208532 chr6:66961280 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.88 -8.21 -0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs950169 0.840 rs4842853 chr15:84942304 G/T cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -5.04 -0.41 1.61e-6 Bipolar disorder; TGCT cis rs4727027 0.704 rs7784122 chr7:148904624 A/G cg23583168 chr7:148888333 NA 0.8 10.65 0.69 3.31e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7917772 0.636 rs4919674 chr10:104522226 T/C cg05855489 chr10:104503620 C10orf26 0.67 5.32 0.43 4.77e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6977660 0.607 rs12113916 chr7:19781424 G/T cg05791153 chr7:19748676 TWISTNB 0.84 4.86 0.4 3.49e-6 Thyroid stimulating hormone; TGCT cis rs8111998 0.826 rs7245719 chr19:22768952 A/T cg19914732 chr19:22715077 NA -0.56 -4.53 -0.38 1.36e-5 Corneal structure; TGCT cis rs425277 0.585 rs2222217 chr1:2063164 G/A cg24578937 chr1:2090814 PRKCZ -0.26 -6.24 -0.49 6.22e-9 Height; TGCT cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs13242816 1.000 rs62471198 chr7:116107963 T/C cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs7524258 0.903 rs4908449 chr1:7292700 T/C cg04342483 chr1:7259290 CAMTA1 -0.31 -4.49 -0.37 1.6e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs2506155 0.715 rs2474712 chr10:33497709 T/C cg25928881 chr10:32632685 EPC1 0.28 4.89 0.4 3.04e-6 Migraine; TGCT cis rs2535633 0.631 rs9823697 chr3:53002150 A/G cg10802521 chr3:52805072 NEK4 -0.53 -5.74 -0.46 6.85e-8 Body mass index; TGCT cis rs9611565 0.592 rs4481089 chr22:41980892 T/C cg03806693 chr22:41940476 POLR3H -1.01 -10.2 -0.68 4.07e-18 Vitiligo; TGCT cis rs523522 0.962 rs10849757 chr12:120964014 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs28595532 1.000 rs115004746 chr4:119642137 C/T cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.78e-7 Cannabis dependence symptom count; TGCT cis rs28374715 0.662 rs28382348 chr15:41487934 G/C cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.6 -0.72 1.65e-21 Ulcerative colitis; TGCT cis rs7923452 0.938 rs67812762 chr10:30759479 G/T cg18806716 chr10:30721971 MAP3K8 0.66 6.06 0.48 1.48e-8 Itch intensity from mosquito bite; TGCT cis rs3820068 0.608 rs6668919 chr1:16049893 A/G cg17385448 chr1:15911702 AGMAT -0.35 -4.64 -0.38 8.6e-6 Systolic blood pressure; TGCT cis rs2997447 0.792 rs61775432 chr1:26416376 A/G cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.16e-5 QRS complex (12-leadsum); TGCT cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg00149659 chr3:10157352 C3orf10 0.93 5.98 0.47 2.25e-8 Alzheimer's disease; TGCT cis rs2180341 0.842 rs6569476 chr6:127553539 G/A cg24812749 chr6:127587940 RNF146 0.92 6.46 0.5 2.18e-9 Breast cancer; TGCT cis rs28595532 0.920 rs116791817 chr4:119763303 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs72781680 1.000 rs72781671 chr2:24231123 A/G cg08917208 chr2:24149416 ATAD2B 0.82 4.92 0.4 2.68e-6 Lymphocyte counts; TGCT cis rs6893807 1.000 rs16903275 chr5:87950543 A/C cg24804195 chr5:87968844 LOC645323 -0.76 -5.82 -0.46 4.69e-8 Body mass index; TGCT cis rs1568657 1.000 rs1568657 chr15:83726179 A/G cg10025586 chr15:83501699 WHAMM -0.24 -4.57 -0.38 1.15e-5 Kawasaki disease; TGCT cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg08439880 chr3:133502540 NA -0.29 -5.42 -0.44 2.93e-7 Iron status biomarkers; TGCT cis rs1862618 0.671 rs72644088 chr5:56241019 G/A cg20203395 chr5:56204925 C5orf35 0.54 5.04 0.41 1.58e-6 Initial pursuit acceleration; TGCT cis rs4372836 1.000 rs7562170 chr2:28943516 T/C cg09522027 chr2:28974177 PPP1CB 0.6 5.06 0.41 1.46e-6 Body mass index; TGCT cis rs55883249 1.000 rs17453724 chr2:9764001 A/G cg23886495 chr2:9695866 ADAM17 0.74 4.45 0.37 1.9e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs8179 0.645 rs11767704 chr7:92256375 C/T cg15732164 chr7:92237376 CDK6 -0.29 -5.05 -0.41 1.57e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs13427251 0.903 rs6746402 chr2:100150443 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.58 -5.51 -0.44 1.97e-7 Chronic sinus infection; TGCT cis rs5769707 0.874 rs9616714 chr22:50050859 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.62 0.38 9.53e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9549367 0.789 rs2287251 chr13:113889499 A/G cg00898013 chr13:113819073 PROZ -0.4 -4.92 -0.4 2.7e-6 Platelet distribution width; TGCT cis rs9341808 0.718 rs12208016 chr6:80823563 G/A cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT trans rs114540395 0.858 rs77325250 chr10:103320638 G/A cg10198749 chr1:39920707 MACF1 0.55 7.05 0.53 1.11e-10 Schizophrenia; TGCT cis rs1215050 0.740 rs1214994 chr4:99035577 C/T cg05340658 chr4:99064831 C4orf37 0.42 5.2 0.42 7.82e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs2727020 0.681 rs2866362 chr11:49379316 A/G cg15704280 chr7:45808275 SEPT13 -0.73 -8.33 -0.6 1.3e-13 Coronary artery disease; TGCT cis rs595982 0.559 rs73061643 chr19:49368151 A/G cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.25 -0.64 8.09e-16 Red cell distribution width; TGCT cis rs9894429 0.634 rs11655346 chr17:79572399 A/G cg18240062 chr17:79603768 NPLOC4 -0.56 -4.92 -0.4 2.67e-6 Eye color traits; TGCT cis rs7584330 0.868 rs13408361 chr2:238382899 A/G cg08992911 chr2:238395768 MLPH 0.64 5.13 0.42 1.07e-6 Prostate cancer; TGCT cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg06481639 chr22:41940642 POLR3H -0.68 -5.81 -0.46 4.87e-8 Vitiligo; TGCT cis rs500492 0.618 rs2473158 chr16:1075241 G/A cg01366354 chr16:1075121 NA 0.35 5.12 0.42 1.11e-6 Polycystic ovary syndrome; TGCT cis rs12681288 0.832 rs2123060 chr8:1009313 T/C cg04851639 chr8:1020857 NA -0.36 -6.29 -0.49 5.07e-9 Schizophrenia; TGCT cis rs10782582 0.593 rs17647178 chr1:76210524 A/G cg03433033 chr1:76189801 ACADM -0.6 -6.63 -0.51 9.16e-10 Daytime sleep phenotypes; TGCT cis rs8072100 0.934 rs6504872 chr17:45438952 C/T cg08085267 chr17:45401833 C17orf57 -0.46 -5.1 -0.42 1.25e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2180341 1.000 rs6569478 chr6:127598619 G/A cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs73099903 0.611 rs7957445 chr12:53408580 A/G cg24505307 chr12:53448429 TENC1 0.39 5.14 0.42 1.06e-6 Systolic blood pressure; TGCT cis rs13256369 0.950 rs13255655 chr8:8577736 C/T cg17143192 chr8:8559678 CLDN23 0.63 5.6 0.45 1.33e-7 Obesity-related traits; TGCT cis rs13188771 0.527 rs365366 chr5:100877873 A/T cg18665594 chr5:101119420 NA 0.44 4.49 0.37 1.62e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs2197308 0.692 rs67352173 chr12:37906912 A/T cg13010199 chr12:38710504 ALG10B 0.61 4.93 0.4 2.57e-6 Morning vs. evening chronotype; TGCT cis rs7225537 0.559 rs11870483 chr17:17016012 G/A cg26176665 chr17:16994978 MPRIP 0.25 5.81 0.46 4.93e-8 Mean platelet volume; TGCT cis rs13242816 1.000 rs987791 chr7:116134701 A/G cg02799643 chr7:116139180 CAV2 -0.46 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs6933660 0.800 rs963193 chr6:151789355 G/T cg10883421 chr6:151773342 RMND1;C6orf211 -0.65 -6.37 -0.5 3.3e-9 Menarche (age at onset); TGCT cis rs17376456 0.877 rs2290937 chr5:93356515 A/T cg21475434 chr5:93447410 FAM172A 0.69 4.79 0.39 4.76e-6 Diabetic retinopathy; TGCT cis rs951366 0.870 rs3747973 chr1:205677148 A/G cg07167872 chr1:205819463 PM20D1 0.41 4.53 0.38 1.39e-5 Menarche (age at onset); TGCT cis rs3749237 0.595 rs11720264 chr3:49580347 C/T cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Cannabis dependence symptom count; TGCT cis rs9790314 0.818 rs6797066 chr3:161008725 T/A cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs7647973 0.961 rs10154992 chr3:49276077 C/T cg05785598 chr3:49045655 WDR6 0.39 4.61 0.38 9.91e-6 Menarche (age at onset); TGCT cis rs3784262 0.528 rs34556514 chr15:58333769 A/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.39 -0.5 3.11e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9733 0.519 rs11587444 chr1:150722844 A/G cg04414720 chr1:150670196 GOLPH3L 0.4 5.21 0.42 7.77e-7 Tonsillectomy; TGCT cis rs7312933 0.558 rs11181422 chr12:42718552 G/A cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.3e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs8141529 0.764 rs5762824 chr22:29222930 C/T cg02153584 chr22:29168773 CCDC117 0.66 5.64 0.45 1.08e-7 Lymphocyte counts; TGCT cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.36 -0.77 8.87e-26 Vitiligo; TGCT cis rs9291683 0.595 rs13150928 chr4:10052961 G/T cg11266682 chr4:10021025 SLC2A9 0.65 8.81 0.62 9.38e-15 Bone mineral density; TGCT cis rs73198271 0.628 rs11783944 chr8:8597801 A/G cg06671706 chr8:8559999 CLDN23 -0.41 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1865760 1.000 rs6905887 chr6:25912103 T/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs926938 0.527 rs360685 chr1:115499795 G/C cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs2354432 0.607 rs3766524 chr1:146729093 A/G cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs7914558 1.000 rs7081075 chr10:104929191 C/T cg05855489 chr10:104503620 C10orf26 0.5 4.47 0.37 1.71e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs539096 0.872 rs674725 chr1:44061795 C/T cg12908607 chr1:44402522 ARTN -0.52 -5.43 -0.44 2.84e-7 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.932 rs6845288 chr4:17665498 A/T cg18681998 chr4:17616180 MED28 -0.94 -9.83 -0.66 3.2e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3008870 1.000 rs2755245 chr1:67487964 C/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.13 0.71 2.26e-20 Lymphocyte percentage of white cells; TGCT cis rs6693567 0.545 rs11205382 chr1:150442466 G/A cg09579323 chr1:150459698 TARS2 -0.52 -4.62 -0.38 9.55e-6 Migraine; TGCT cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs7772486 0.720 rs1890171 chr6:146072114 T/C cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs202629 1 rs202629 chr22:41849975 C/T cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Cannabis dependence symptom count; TGCT cis rs11644362 0.631 rs8054655 chr16:12965215 T/A cg06890432 chr16:12997467 SHISA9 -0.46 -4.64 -0.38 8.64e-6 Positive affect;Subjective well-being; TGCT cis rs597539 0.580 rs7935851 chr11:68731122 A/G cg06028808 chr11:68637592 NA 0.56 7.3 0.55 2.99e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs11097606 chr4:99011486 C/T cg18180107 chr4:99064573 C4orf37 0.51 4.64 0.38 8.77e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs858239 0.601 rs11982002 chr7:23163270 C/T cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1401999 0.724 rs1016752 chr3:183665062 C/G cg01324343 chr3:183735012 ABCC5 -0.68 -8.24 -0.59 2.08e-13 Anterior chamber depth; TGCT cis rs782590 0.967 rs1975484 chr2:55803167 T/A cg03859395 chr2:55845619 SMEK2 0.92 11.39 0.72 5.08e-21 Metabolic syndrome; TGCT cis rs11112613 0.713 rs11112589 chr12:105951226 C/G cg03607813 chr12:105948248 NA -0.49 -5.87 -0.47 3.8e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.56 5.09 0.42 1.3e-6 Prudent dietary pattern; TGCT cis rs7267979 0.873 rs6115093 chr20:25210730 C/T cg14121845 chr20:25566513 NINL 0.5 5.52 0.44 1.9e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17253792 0.822 rs80085988 chr14:56096173 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs709400 0.633 rs1136165 chr14:103988180 G/T cg12935359 chr14:103987150 CKB 0.4 5.86 0.47 3.96e-8 Body mass index; TGCT cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg15659132 chr6:26577336 NA -0.56 -5.55 -0.45 1.62e-7 Schizophrenia; TGCT cis rs16854884 0.770 rs1445417 chr3:143808972 A/T cg06585982 chr3:143692056 C3orf58 0.57 4.49 0.37 1.63e-5 Economic and political preferences (feminism/equality); TGCT cis rs2688608 0.592 rs2306328 chr10:75579510 C/T cg19442545 chr10:75533431 FUT11 -0.36 -5.67 -0.45 9.61e-8 Inflammatory bowel disease; TGCT cis rs7552404 0.924 rs7544117 chr1:76158246 A/G cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2239547 0.563 rs9839035 chr3:52909877 C/T cg11645453 chr3:52864694 ITIH4 0.34 5.72 0.46 7.68e-8 Schizophrenia; TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg01802117 chr1:53393560 SCP2 0.38 4.6 0.38 1.04e-5 Monocyte count; TGCT cis rs12477438 0.520 rs8179690 chr2:99795300 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.88 -8.77 -0.62 1.17e-14 Chronic sinus infection; TGCT cis rs9549367 0.713 rs3024744 chr13:113821477 A/C cg00898013 chr13:113819073 PROZ -0.53 -6.77 -0.52 4.62e-10 Platelet distribution width; TGCT trans rs73411413 0.661 rs11599981 chr11:1520063 C/T cg13381631 chr10:46776799 NA -0.39 -6.85 -0.52 3.08e-10 Myringotomy; TGCT cis rs13242816 1.000 rs987790 chr7:116134633 T/A cg16553024 chr7:116138462 CAV2 -0.45 -5.06 -0.41 1.49e-6 P wave duration; TGCT cis rs10782582 0.593 rs6704444 chr1:76205108 T/C cg03433033 chr1:76189801 ACADM -0.61 -6.63 -0.51 9.47e-10 Daytime sleep phenotypes; TGCT cis rs3812831 0.695 rs3118895 chr13:114931742 G/A cg08824895 chr13:115047677 UPF3A 0.51 4.98 0.41 2.07e-6 Schizophrenia; TGCT cis rs4372836 0.615 rs61407258 chr2:29046909 A/G cg09522027 chr2:28974177 PPP1CB -0.67 -6.97 -0.53 1.66e-10 Body mass index; TGCT cis rs6733011 0.578 rs6714243 chr2:99510039 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.78 -0.39 4.87e-6 Bipolar disorder; TGCT cis rs10791097 0.694 rs11222370 chr11:130744767 T/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs765787 0.530 rs4775831 chr15:45534722 A/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs138249 0.527 rs138251 chr22:50570852 A/G cg16473166 chr22:50639996 SELO 0.64 4.51 0.38 1.48e-5 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs7100689 0.646 rs1340380 chr10:82115619 T/C cg01528321 chr10:82214614 TSPAN14 0.81 7.83 0.58 1.9e-12 Post bronchodilator FEV1; TGCT cis rs7552404 0.727 rs5745427 chr1:76332637 C/A cg22875332 chr1:76189707 ACADM -0.57 -6.14 -0.48 1.05e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10791097 0.694 rs4370948 chr11:130755700 A/C cg12179176 chr11:130786555 SNX19 0.83 10.34 0.68 1.85e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg19318889 chr4:1322082 MAEA 0.28 6.71 0.52 6.05e-10 Longevity; TGCT cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 8.4 0.6 8.57e-14 Platelet count; TGCT cis rs9902453 0.612 rs2617868 chr17:28073247 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.4 -0.6 8.88e-14 Coffee consumption (cups per day); TGCT cis rs9486715 0.838 rs7770889 chr6:96858453 C/T cg18709589 chr6:96969512 KIAA0776 -0.73 -6.59 -0.51 1.13e-9 Headache; TGCT cis rs4851254 0.961 rs11677607 chr2:100751150 C/T cg04109781 chr2:100722022 AFF3 0.45 4.8 0.4 4.51e-6 Intelligence (multi-trait analysis); TGCT cis rs7100689 0.646 rs1934696 chr10:82124966 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs8017423 0.967 rs12896540 chr14:90729392 T/C cg04374321 chr14:90722782 PSMC1 -0.75 -7.37 -0.55 2.14e-11 Mortality in heart failure; TGCT cis rs7714584 1.000 rs10057988 chr5:150272062 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs611744 0.647 rs702808 chr8:109252554 T/C cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs6121246 0.567 rs7266471 chr20:30220599 T/A cg21427119 chr20:30132790 HM13 -0.43 -6.02 -0.48 1.86e-8 Mean corpuscular hemoglobin; TGCT cis rs7666738 0.800 rs2839836 chr4:98970512 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.683 rs7459925 chr8:58111771 G/A cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs763014 0.966 rs35642938 chr16:642249 T/C cg27436995 chr16:743998 FBXL16 -0.45 -4.86 -0.4 3.48e-6 Height; TGCT cis rs7833790 0.632 rs6473308 chr8:82707708 G/A cg17211192 chr8:82754475 SNX16 -0.95 -8.69 -0.62 1.78e-14 Diastolic blood pressure; TGCT cis rs11673344 0.504 rs8111285 chr19:37623649 A/G cg08039142 chr19:36980659 ZNF566 0.51 4.68 0.39 7.31e-6 Obesity-related traits; TGCT cis rs6460942 0.908 rs59410610 chr7:12282847 A/G cg06484146 chr7:12443880 VWDE -0.54 -4.71 -0.39 6.5e-6 Coronary artery disease; TGCT cis rs17345786 0.906 rs12638137 chr3:101150964 C/T cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT trans rs8073060 0.671 rs9894813 chr17:33873848 C/T cg19694781 chr19:47549865 TMEM160 0.48 9.37 0.64 4.24e-16 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg08859206 chr1:53392774 SCP2 0.41 5.98 0.47 2.19e-8 Monocyte count; TGCT cis rs6484504 0.600 rs12796587 chr11:31266443 T/C cg26647111 chr11:31128758 NA -0.35 -4.85 -0.4 3.58e-6 Red blood cell count; TGCT cis rs6087771 0.781 rs6089067 chr20:30358894 G/C cg18721089 chr20:30220636 NA -0.35 -4.52 -0.38 1.4e-5 Subcortical brain region volumes;Putamen volume; TGCT cis rs9303401 0.659 rs7223708 chr17:56896398 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs11098499 0.754 rs2036860 chr4:120248934 A/G cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs13242816 1.000 rs35364754 chr7:116109716 T/G cg16553024 chr7:116138462 CAV2 -0.44 -4.53 -0.38 1.34e-5 P wave duration; TGCT cis rs35146811 0.624 rs1727134 chr7:99813672 T/C cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs1008375 1.000 rs4235388 chr4:17682030 G/A cg18681998 chr4:17616180 MED28 0.91 10.3 0.68 2.41e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 4.9 0.4 2.9e-6 Menopause (age at onset); TGCT cis rs5771225 0.563 rs5771281 chr22:50693479 A/G cg16473166 chr22:50639996 SELO 0.69 5.69 0.45 8.74e-8 Late-onset Alzheimer's disease; TGCT cis rs10791097 0.703 rs11222360 chr11:130730871 C/T cg14779329 chr11:130786720 SNX19 0.26 4.61 0.38 9.93e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9952991 0.566 rs534911 chr18:12857335 G/A cg23544223 chr18:12777786 NA 0.54 4.71 0.39 6.43e-6 Inflammatory skin disease; TGCT cis rs75686122 0.772 rs79344235 chr8:104509998 G/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs1891275 0.515 rs10881957 chr10:93501876 C/T cg07889827 chr10:93443413 NA -0.32 -6.85 -0.52 3.03e-10 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg06238570 chr21:40685208 BRWD1 -0.76 -6.96 -0.53 1.74e-10 Cognitive function; TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs4862750 0.914 rs1991255 chr4:187875340 G/A cg10295955 chr4:187884368 NA -0.97 -14.69 -0.8 6.27e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs9583531 0.689 rs6492308 chr13:111377829 T/C cg24331049 chr13:111365604 ING1 0.88 8.89 0.62 6e-15 Coronary artery disease; TGCT cis rs9435341 0.965 rs1730862 chr1:107614003 G/A cg09367891 chr1:107599246 PRMT6 -0.62 -5.17 -0.42 8.93e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs9443189 0.570 rs775072 chr6:76377998 G/A cg01950844 chr6:76311363 SENP6 -1.0 -6.24 -0.49 6.35e-9 Prostate cancer; TGCT cis rs250677 0.958 rs17109282 chr5:148416677 A/G cg23229984 chr5:148520753 ABLIM3 -0.2 -4.66 -0.39 8.06e-6 Breast cancer; TGCT cis rs71435601 0.657 rs67599264 chr2:21418083 G/A cg25035485 chr2:21266500 APOB -0.52 -4.45 -0.37 1.92e-5 Cholesterol, total; TGCT cis rs2239547 0.522 rs2581797 chr3:52972468 C/T cg11645453 chr3:52864694 ITIH4 -0.33 -5.34 -0.43 4.35e-7 Schizophrenia; TGCT cis rs2180341 1.000 rs9385419 chr6:127597591 A/G cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs12497850 0.931 rs13064911 chr3:48952385 A/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs6582630 0.555 rs10880624 chr12:38526316 C/T cg13010199 chr12:38710504 ALG10B 0.62 4.95 0.41 2.37e-6 Drug-induced liver injury (flucloxacillin); TGCT trans rs1814175 0.781 rs2866734 chr11:49886338 A/G cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs4730250 0.595 rs7789500 chr7:106915723 A/C cg02696742 chr7:106810147 HBP1 -0.68 -5.2 -0.42 8.03e-7 Osteoarthritis; TGCT cis rs6666258 1.000 rs6426986 chr1:154814045 G/A cg06418219 chr1:154948305 SHC1;CKS1B 0.62 5.04 0.41 1.59e-6 Atrial fibrillation; TGCT cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.9 -0.4 2.9e-6 Bipolar disorder; TGCT cis rs12291225 0.679 rs11023172 chr11:14295367 C/G cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.56 4.76 0.39 5.25e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2180341 0.814 rs7768435 chr6:127737038 A/C cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs12451471 0.667 rs12942002 chr17:78101629 C/G cg06718696 chr17:78121285 EIF4A3 0.77 6.43 0.5 2.47e-9 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs11018874 0.532 rs11018867 chr11:89862345 C/T cg05041596 chr11:89867385 NAALAD2 0.52 5.21 0.42 7.6e-7 White blood cell types; TGCT trans rs6089829 0.925 rs6122086 chr20:61664528 T/C cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs12950390 0.893 rs4239165 chr17:45847272 A/T cg06532163 chr17:45867833 NA 0.34 5.31 0.43 4.82e-7 IgG glycosylation; TGCT cis rs12049351 0.774 rs4925456 chr1:229623896 A/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7095607 0.813 rs7895737 chr10:69924146 A/G cg18986048 chr10:69913749 MYPN 0.48 5.57 0.45 1.54e-7 Lung function (FVC); TGCT cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg09323728 chr8:95962352 TP53INP1 -0.54 -6.91 -0.53 2.26e-10 Type 2 diabetes; TGCT cis rs1371867 0.875 rs1788174 chr8:101330957 C/G cg06002616 chr8:101225028 SPAG1 0.54 6.37 0.5 3.31e-9 Atrioventricular conduction; TGCT cis rs892961 1.000 rs1075457 chr17:75400737 A/G cg05865280 chr17:75406074 SEPT9 -0.28 -6.6 -0.51 1.06e-9 Airflow obstruction; TGCT cis rs13191362 1.000 rs67094146 chr6:163145412 G/C cg06582575 chr6:163149167 PACRG;PARK2 1.0 7.64 0.57 5.11e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12477438 0.520 rs4347885 chr2:99804007 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs2760061 0.626 rs2527614 chr1:228126470 A/G cg18477163 chr1:228402036 OBSCN -0.32 -6.38 -0.5 3.25e-9 Diastolic blood pressure; TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg19626725 chr5:178986131 RUFY1 -0.51 -6.84 -0.52 3.22e-10 Lung cancer; TGCT cis rs7666738 0.830 rs1813642 chr4:98852225 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.38 0.43 3.58e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2721195 0.654 rs4610795 chr8:145881333 C/T cg11211951 chr8:145729740 GPT -0.21 -4.71 -0.39 6.53e-6 Age at first birth; TGCT cis rs875971 0.619 rs12533585 chr7:65984605 G/C cg00343986 chr7:65444356 GUSB 0.24 5.29 0.43 5.43e-7 Aortic root size; TGCT cis rs7666738 0.546 rs1863602 chr4:98909304 T/C cg17366294 chr4:99064904 C4orf37 0.66 6.02 0.48 1.83e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6500602 0.627 rs841231 chr16:4583147 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.39 -5.69 -0.45 8.79e-8 Schizophrenia; TGCT cis rs12210905 1.000 rs3800310 chr6:27206843 C/G cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT cis rs3806843 0.966 rs7737424 chr5:140146345 C/T cg19875535 chr5:140030758 IK 0.36 6.17 0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7586879 0.789 rs36029941 chr2:25127801 C/T cg01884057 chr2:25150051 NA 0.27 4.72 0.39 6.29e-6 Body mass index; TGCT cis rs12762955 0.561 rs7918118 chr10:1042823 C/A cg18964960 chr10:1102726 WDR37 -0.69 -6.08 -0.48 1.35e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs8135665 0.600 rs8139025 chr22:38450881 G/C cg13116946 chr22:38479732 SLC16A8 0.28 5.55 0.45 1.63e-7 Advanced age-related macular degeneration;Age-related macular degeneration; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg15242686 chr22:24348715 GSTTP1 0.48 6.96 0.53 1.77e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs904251 0.504 rs2797795 chr6:37480683 T/C cg25019722 chr6:37503610 NA -0.53 -8.19 -0.59 2.75e-13 Cognitive performance; TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.89 0.4 3.01e-6 Prudent dietary pattern; TGCT cis rs8077577 0.895 rs62072468 chr17:18118179 A/G cg09161412 chr17:18057145 MYO15A -0.6 -4.79 -0.4 4.61e-6 Obesity-related traits; TGCT cis rs2742417 0.603 rs2742374 chr3:45784082 T/C cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7226408 0.948 rs4368229 chr18:34395243 A/G cg06757138 chr18:34340585 FHOD3 -0.25 -4.57 -0.38 1.17e-5 Obesity-related traits; TGCT cis rs78487399 0.808 rs6544668 chr2:43732488 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.5 0.37 1.57e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10782582 0.609 rs78776851 chr1:76424845 T/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.56 4.95 0.41 2.4e-6 Daytime sleep phenotypes; TGCT cis rs1129187 0.702 rs2395943 chr6:42940673 A/G cg13397359 chr6:42928475 GNMT 0.58 4.89 0.4 3.02e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs36051895 0.589 rs11790596 chr9:5198335 T/C cg02405213 chr9:5042618 JAK2 -0.76 -9.91 -0.66 2.13e-17 Pediatric autoimmune diseases; TGCT cis rs9467711 0.606 rs28362606 chr6:26365586 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2075371 0.796 rs1646644 chr7:134011817 A/T cg11752832 chr7:134001865 SLC35B4 0.72 6.22 0.49 7.09e-9 Mean platelet volume; TGCT cis rs10489202 0.632 rs202268 chr1:167927339 T/C cg24449463 chr1:168025552 DCAF6 -0.59 -7.02 -0.53 1.29e-10 Schizophrenia; TGCT cis rs9372498 0.536 rs62424199 chr6:118827252 G/A cg07617317 chr6:118971624 C6orf204 0.47 5.1 0.42 1.23e-6 Diastolic blood pressure; TGCT cis rs2404618 0.557 rs2906578 chr8:1508963 T/C cg13402656 chr8:1511478 DLGAP2 -0.45 -8.95 -0.63 4.26e-15 Lung cancer; TGCT cis rs4851266 0.966 rs4851270 chr2:100832656 T/C cg22139774 chr2:100720529 AFF3 -0.34 -5.09 -0.42 1.28e-6 Educational attainment; TGCT cis rs13242816 1.000 rs6979182 chr7:116119345 T/G cg02799643 chr7:116139180 CAV2 -0.49 -5.55 -0.45 1.66e-7 P wave duration; TGCT cis rs9811920 0.638 rs1688782 chr3:99630527 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.57 6.77 0.52 4.59e-10 Axial length; TGCT cis rs6424115 0.737 rs10917430 chr1:24170458 C/T cg15997130 chr1:24165203 NA -0.71 -7.19 -0.54 5.43e-11 Immature fraction of reticulocytes; TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg27535305 chr1:53392650 SCP2 -0.28 -5.36 -0.43 3.92e-7 Monocyte count; TGCT cis rs77633900 0.614 rs280005 chr15:77009185 G/C cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs6696846 0.765 rs2836 chr1:205111761 G/T cg03948781 chr1:205179583 DSTYK -0.34 -4.51 -0.38 1.51e-5 Red blood cell count; TGCT cis rs6121246 0.909 rs6060644 chr20:30265652 G/A cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs8180040 0.593 rs12715421 chr3:47084859 A/G cg27129171 chr3:47204927 SETD2 0.71 8.51 0.61 4.8e-14 Colorectal cancer; TGCT cis rs72781680 0.898 rs72782106 chr2:24022009 A/G cg08917208 chr2:24149416 ATAD2B 0.93 5.84 0.46 4.22e-8 Lymphocyte counts; TGCT cis rs4916646 0.668 rs13117158 chr4:11516839 A/G cg16957523 chr4:11431359 HS3ST1 -0.47 -4.66 -0.39 8.08e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs35306767 0.855 rs12761180 chr10:872086 C/T cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT trans rs1864729 0.688 rs1540434 chr8:98305351 A/G cg08679828 chr8:102218111 ZNF706 -1.02 -6.67 -0.51 7.5e-10 Estradiol plasma levels (breast cancer); TGCT cis rs231513 1.000 rs231519 chr17:41961051 C/T cg26893861 chr17:41843967 DUSP3 0.73 5.35 0.43 4.16e-7 Cognitive function; TGCT cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg24531977 chr5:56204891 C5orf35 -0.76 -7.66 -0.57 4.53e-12 Initial pursuit acceleration; TGCT cis rs72634258 0.554 rs12061787 chr1:7888730 G/C cg26816564 chr1:7831052 VAMP3 0.87 6.44 0.5 2.34e-9 Inflammatory bowel disease; TGCT cis rs151997 0.671 rs152926 chr5:50201787 G/A cg06027927 chr5:50259733 NA -0.54 -5.49 -0.44 2.14e-7 Callous-unemotional behaviour; TGCT cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg03264133 chr6:25882463 NA -0.65 -5.98 -0.47 2.26e-8 Intelligence (multi-trait analysis); TGCT cis rs2932538 0.922 rs6537745 chr1:113154080 T/C cg22162597 chr1:113214053 CAPZA1 0.25 5.6 0.45 1.34e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2013441 0.804 rs1811453 chr17:20232193 A/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.64 -6.63 -0.51 9.03e-10 Intelligence (multi-trait analysis); TGCT cis rs6964587 1.000 rs6942649 chr7:91594510 A/G cg17063962 chr7:91808500 NA 0.83 8.16 0.59 3.1e-13 Breast cancer; TGCT cis rs3749237 0.964 rs2234385 chr3:49846041 G/A cg03060546 chr3:49711283 APEH 0.69 7.12 0.54 7.8e-11 Resting heart rate; TGCT cis rs7954584 0.583 rs10770186 chr12:122361412 A/G cg21171335 chr12:122356390 WDR66 0.59 6.19 0.49 8.15e-9 Mean corpuscular volume; TGCT cis rs6952808 0.723 rs11766575 chr7:2005747 T/C cg04267008 chr7:1944627 MAD1L1 -0.36 -4.72 -0.39 6.26e-6 Bipolar disorder and schizophrenia; TGCT cis rs6831352 0.918 rs35784540 chr4:100061692 T/A cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs10791097 0.694 rs10791100 chr11:130738946 T/A cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2153535 0.580 rs9406172 chr6:8515464 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs7829975 0.714 rs4841040 chr8:8654527 T/C cg08975724 chr8:8085496 FLJ10661 0.57 4.96 0.41 2.22e-6 Mood instability; TGCT cis rs74544699 1.000 rs353029 chr4:74776804 C/T cg16072462 chr4:74847758 PF4 0.99 4.52 0.38 1.4e-5 Growth-regulated protein alpha levels; TGCT cis rs2594989 0.943 rs2454508 chr3:11493232 T/C cg26283222 chr3:11613257 VGLL4 -0.21 -4.46 -0.37 1.84e-5 Circulating chemerin levels; TGCT cis rs6977955 1.000 rs917117 chr7:28176305 G/A cg23620719 chr7:28220237 JAZF1 0.67 5.05 0.41 1.52e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12900413 0.603 rs2351494 chr15:90299541 C/T cg24249390 chr15:90295951 MESP1 -0.29 -5.03 -0.41 1.7e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7429990 0.895 rs35790549 chr3:48071488 A/T cg11946769 chr3:48343235 NME6 0.64 5.12 0.42 1.13e-6 Educational attainment (years of education); TGCT cis rs9985766 1.000 rs9992748 chr4:151037795 C/A cg05926478 chr4:151174724 DCLK2 -0.27 -4.81 -0.4 4.35e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs289997 0.920 rs905385 chr7:25576737 G/C cg14064488 chr7:26331273 SNX10 0.36 5.19 0.42 8.28e-7 Breast cancer; TGCT cis rs11098499 0.575 rs907205 chr4:120238664 G/C cg09307838 chr4:120376055 NA 0.61 5.84 0.46 4.35e-8 Corneal astigmatism; TGCT cis rs9611565 0.512 rs2050033 chr22:42159229 G/T cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs4888262 0.545 rs4588013 chr16:74703388 C/T cg01733217 chr16:74700730 RFWD3 0.77 7.77 0.57 2.57e-12 Testicular germ cell tumor; TGCT cis rs4727027 0.870 rs13237714 chr7:148884083 A/G cg23583168 chr7:148888333 NA -0.74 -9.81 -0.66 3.64e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9399135 0.622 rs3817776 chr6:135256756 C/T cg24558204 chr6:135376177 HBS1L -0.46 -5.0 -0.41 1.92e-6 Red blood cell count; TGCT cis rs7226408 0.948 rs11664088 chr18:34380417 C/A cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs2486288 0.656 rs8039138 chr15:45551592 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs10875746 0.951 rs7485355 chr12:48548342 G/A cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs807669 0.565 rs5746682 chr22:19185526 C/T cg02655711 chr22:19163373 SLC25A1 0.33 6.81 0.52 3.82e-10 Metabolite levels; TGCT cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs13119995 chr4:99026790 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4253772 0.638 rs6007845 chr22:46718417 A/T cg26492175 chr22:47022658 GRAMD4 -0.19 -4.5 -0.37 1.54e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs7666738 0.830 rs13138063 chr4:99050438 A/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7824557 0.606 rs2736273 chr8:11199938 C/A cg21775007 chr8:11205619 TDH 0.73 6.81 0.52 3.72e-10 Retinal vascular caliber; TGCT cis rs367943 0.966 rs451425 chr5:112808637 A/G cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs11599315 0.507 rs12218307 chr10:1341914 G/A cg27336068 chr10:1336103 ADARB2 -0.34 -5.47 -0.44 2.41e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs10791323 0.569 rs1944734 chr11:133720077 G/A cg15485101 chr11:133734466 NA 0.43 5.39 0.44 3.41e-7 Childhood ear infection; TGCT cis rs4727027 0.782 rs10245343 chr7:148796333 T/C cg15662616 chr7:148823355 ZNF425;ZNF398 0.57 4.74 0.39 5.72e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9393777 0.546 rs9366673 chr6:26893329 C/G cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.54 -5.03 -0.41 1.7e-6 Intelligence (multi-trait analysis); TGCT cis rs13256369 0.851 rs13254997 chr8:8563753 G/C cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs7586879 0.681 rs6545790 chr2:25109302 A/G cg01884057 chr2:25150051 NA 0.35 6.55 0.51 1.39e-9 Body mass index; TGCT cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs13122456 chr4:98936011 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs477895 0.838 rs2070765 chr11:64010085 A/G cg04317338 chr11:64019027 PLCB3 0.8 6.81 0.52 3.73e-10 Mean platelet volume; TGCT cis rs3772130 0.962 rs28660600 chr3:121482637 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs377070 0.844 rs309415 chr4:123621228 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.44 4.94 0.41 2.49e-6 Mosquito bite size; TGCT cis rs9322193 0.923 rs10782315 chr6:150064229 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs7833790 0.632 rs6473308 chr8:82707708 G/A cg27398817 chr8:82754497 SNX16 -0.66 -5.22 -0.42 7.25e-7 Diastolic blood pressure; TGCT cis rs1403694 1.000 rs1624230 chr3:186438935 A/C cg12454167 chr3:186435060 KNG1 -0.42 -7.26 -0.55 3.73e-11 Blood protein levels; TGCT cis rs9921338 0.961 rs17605444 chr16:11413589 A/C cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs12048904 0.512 rs932798 chr1:101249355 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.8 -7.06 -0.54 1.06e-10 Multiple sclerosis; TGCT cis rs7412746 0.611 rs6660084 chr1:150748803 T/C cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs2839186 0.504 rs11702278 chr21:47936295 T/G cg10657630 chr21:48055338 PRMT2 0.49 4.73 0.39 5.91e-6 Testicular germ cell tumor; TGCT cis rs62380364 0.565 rs617944 chr5:88057915 T/C cg22951263 chr5:87985283 NA -0.59 -6.27 -0.49 5.5e-9 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg23131131 chr22:24373011 LOC391322 0.62 6.24 0.49 6.18e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2594989 0.943 rs2442780 chr3:11510568 A/G cg00170343 chr3:11313890 ATG7 0.69 5.1 0.42 1.21e-6 Circulating chemerin levels; TGCT cis rs7226408 0.857 rs72890574 chr18:34623479 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs11969893 0.649 rs9485415 chr6:101279459 C/T cg12253828 chr6:101329408 ASCC3 1.08 5.24 0.43 6.59e-7 Economic and political preferences (immigration/crime); TGCT cis rs9810089 0.843 rs11717954 chr3:136112109 A/G cg12473912 chr3:136751656 NA 0.37 5.15 0.42 9.8e-7 Gestational age at birth (child effect); TGCT cis rs3617 0.573 rs12638968 chr3:52919447 T/A cg11645453 chr3:52864694 ITIH4 -0.27 -5.17 -0.42 9.18e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg17775962 chr7:1200435 ZFAND2A 0.28 4.86 0.4 3.46e-6 Longevity;Endometriosis; TGCT cis rs425277 0.565 rs2480711 chr1:2111376 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.48 -0.37 1.7e-5 Height; TGCT cis rs6762 0.748 rs28735718 chr11:839629 A/G cg16425592 chr11:842748 TSPAN4;POLR2L -0.45 -4.5 -0.37 1.53e-5 Mean platelet volume; TGCT cis rs10089 0.904 rs2195921 chr5:127489754 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.64e-13 Ileal carcinoids; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg06753367 chr22:24256600 NA 0.24 4.51 0.38 1.5e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3733585 0.673 rs6843873 chr4:9958788 A/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10197940 0.662 rs72860233 chr2:152289767 G/A cg06191203 chr2:152266755 RIF1 -0.78 -7.31 -0.55 2.89e-11 Lung cancer; TGCT cis rs6545883 0.895 rs2442029 chr2:61679552 G/T cg15711740 chr2:61764176 XPO1 -0.56 -5.1 -0.42 1.23e-6 Tuberculosis; TGCT cis rs909674 0.541 rs5757655 chr22:39797178 C/G cg05872129 chr22:39784769 NA 0.99 11.49 0.72 2.91e-21 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4654899 0.865 rs6693020 chr1:21378057 A/G cg01072550 chr1:21505969 NA -0.47 -6.96 -0.53 1.72e-10 Superior frontal gyrus grey matter volume; TGCT trans rs551517 0.560 rs547116 chr9:113640132 T/A cg18410444 chr5:89825535 LYSMD3 0.67 6.83 0.52 3.39e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs9929218 0.953 rs3118227 chr16:68734855 G/A cg01251360 chr16:68772225 CDH1 0.3 4.8 0.4 4.45e-6 Colorectal cancer; TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg04389838 chr3:44770851 ZNF501 -0.4 -5.36 -0.43 3.92e-7 Depressive symptoms; TGCT cis rs7133214 0.510 rs4931479 chr12:27948615 A/G cg16706260 chr12:27849370 REP15 0.28 5.18 0.42 8.76e-7 Gut microbiota (functional units); TGCT cis rs634534 0.591 rs688862 chr11:65733393 A/G cg17985854 chr11:65770987 BANF1;EIF1AD 0.24 5.23 0.43 6.85e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7614311 0.731 rs1053338 chr3:63967900 A/G cg22134162 chr3:63841271 THOC7 -0.45 -5.73 -0.46 7.3e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs7666738 0.830 rs17558193 chr4:99049593 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 1.000 rs6460292 chr7:65810075 G/A cg18876405 chr7:65276391 NA -0.32 -4.93 -0.4 2.63e-6 Aortic root size; TGCT cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs11785400 0.963 rs6990126 chr8:143728387 T/C cg24634471 chr8:143751801 JRK 0.55 5.92 0.47 2.93e-8 Schizophrenia; TGCT trans rs4650994 0.544 rs2476561 chr1:178619900 C/T cg05059571 chr16:84539110 KIAA1609 -0.5 -9.61 -0.65 1.14e-16 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4975709 0.609 rs2232373 chr5:1882280 C/G cg14773178 chr5:1868261 NA 0.36 4.88 0.4 3.16e-6 Cardiovascular disease risk factors; TGCT cis rs12477438 0.520 rs6708576 chr2:99801308 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg08736216 chr1:53307985 ZYG11A -0.29 -6.09 -0.48 1.32e-8 Monocyte count; TGCT cis rs6570726 0.902 rs373321 chr6:145854150 T/A cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6722750 0.846 rs34923691 chr2:64395183 C/T cg22352474 chr2:64371530 PELI1 0.7 6.63 0.51 9.46e-10 Neuroticism; TGCT cis rs12477438 0.748 rs10200974 chr2:99675227 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs2463822 0.748 rs2513038 chr11:62081329 A/C cg06239285 chr11:62104954 ASRGL1 0.92 6.16 0.48 9.2e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs1171582 0.545 rs10821585 chr10:61516587 G/A cg23572703 chr10:62241191 NA -0.28 -4.58 -0.38 1.1e-5 Alopecia areata; TGCT cis rs4494114 1.000 rs9439084 chr1:39345017 A/C cg25970120 chr1:39325951 RRAGC -0.6 -6.23 -0.49 6.58e-9 Blood protein levels; TGCT cis rs6430585 0.702 rs3213890 chr2:136552188 G/A cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs1218582 0.682 rs12046459 chr1:154912017 A/C cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.09 -0.54 8.92e-11 Prostate cancer; TGCT cis rs7666738 0.830 rs6853266 chr4:99047528 G/T cg17366294 chr4:99064904 C4orf37 0.78 8.09 0.59 4.52e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs62064224 0.614 rs9916114 chr17:30766950 T/C cg18200150 chr17:30822561 MYO1D 0.44 5.28 0.43 5.61e-7 Schizophrenia; TGCT cis rs9549260 0.564 rs9549280 chr13:41322660 T/C cg21288729 chr13:41239152 FOXO1 0.91 8.25 0.6 2.01e-13 Red blood cell count; TGCT cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 6.19 0.49 7.91e-9 Schizophrenia; TGCT cis rs11112613 0.713 rs73184084 chr12:105952615 T/A cg03607813 chr12:105948248 NA 0.47 5.72 0.46 7.49e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs950169 0.541 rs10795 chr15:85177297 G/A cg17173187 chr15:85201210 NMB 0.62 7.09 0.54 8.99e-11 Schizophrenia; TGCT cis rs524023 0.957 rs552307 chr11:64357539 G/A cg07733098 chr11:64478343 NRXN2 -0.31 -4.64 -0.38 8.56e-6 Urate levels in obese individuals; TGCT cis rs12776158 0.901 rs61848384 chr10:71215225 T/G cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg10117171 chr1:25599238 RHD -0.36 -5.86 -0.47 3.99e-8 Erythrocyte sedimentation rate; TGCT cis rs245880 0.702 rs245884 chr7:29188475 T/G cg17163760 chr7:29186267 CPVL -0.44 -5.54 -0.45 1.73e-7 Warfarin maintenance dose; TGCT cis rs593982 1.000 rs1941746 chr11:65502413 A/G cg08755490 chr11:65554678 OVOL1 1.42 12.09 0.74 1.03e-22 Atopic dermatitis; TGCT cis rs3892630 0.824 rs35654350 chr19:33223766 T/C cg22980127 chr19:33182716 NUDT19 0.71 5.15 0.42 9.79e-7 Red blood cell traits; TGCT cis rs10193935 0.901 rs10490552 chr2:42559947 C/T cg27598129 chr2:42591480 NA 0.36 5.22 0.42 7.19e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs911263 0.603 rs11628954 chr14:68782604 C/T cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs9788682 1.000 rs57064725 chr15:78833036 C/A cg24631222 chr15:78858424 CHRNA5 0.92 7.57 0.56 7.51e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7246657 0.663 rs4803276 chr19:38072330 C/A cg03611452 chr19:38183253 ZNF781 0.6 4.83 0.4 3.97e-6 Coronary artery calcification; TGCT cis rs2280018 0.538 rs7404526 chr16:15129162 A/G cg07549590 chr16:15018862 NA -0.31 -4.57 -0.38 1.15e-5 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs8077889 0.871 rs7212648 chr17:41917962 A/C cg26893861 chr17:41843967 DUSP3 1.11 12.84 0.76 1.62e-24 Triglycerides; TGCT cis rs896854 0.846 rs13254283 chr8:95914103 G/T cg23172400 chr8:95962367 TP53INP1 -0.34 -5.61 -0.45 1.27e-7 Type 2 diabetes; TGCT cis rs12135062 0.901 rs2651928 chr1:3101722 C/T cg21609526 chr1:3105151 PRDM16 -0.38 -6.34 -0.5 3.79e-9 Migraine; TGCT cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg17345569 chr6:42928274 GNMT -0.48 -4.97 -0.41 2.22e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7666738 0.791 rs34790496 chr4:98930516 C/T cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs137699 1.000 rs5757632 chr22:39756097 A/C cg05872129 chr22:39784769 NA -0.56 -4.85 -0.4 3.64e-6 IgG glycosylation; TGCT cis rs492146 0.935 rs316135 chr6:52846777 C/T cg06706454 chr6:52930286 FBXO9 -0.47 -4.54 -0.38 1.32e-5 Epilepsy (remission after treatment); TGCT cis rs1969363 0.509 rs8189633 chr12:38065155 C/G cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Morning vs. evening chronotype; TGCT cis rs7027203 0.828 rs3996239 chr9:96611290 T/A cg14598338 chr9:96623480 NA -0.61 -9.56 -0.65 1.44e-16 DNA methylation (variation); TGCT cis rs9527 0.637 rs7085104 chr10:104628873 A/G cg15744005 chr10:104629667 AS3MT -0.51 -6.54 -0.51 1.47e-9 Arsenic metabolism; TGCT cis rs826838 0.586 rs1843903 chr12:38627524 C/T cg26384229 chr12:38710491 ALG10B 0.62 5.71 0.46 8e-8 Heart rate; TGCT cis rs71435601 0.689 rs10169543 chr2:21423989 T/C cg25035485 chr2:21266500 APOB -0.55 -4.68 -0.39 7.46e-6 Cholesterol, total; TGCT cis rs78707713 0.524 rs10823377 chr10:71213327 G/A cg12610070 chr10:71211762 TSPAN15 -0.58 -7.0 -0.53 1.41e-10 Venous thromboembolism; TGCT cis rs6921919 0.583 rs13201726 chr6:28385551 T/A cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9372498 0.831 rs62421532 chr6:118705454 A/T cg21191810 chr6:118973309 C6orf204 -0.5 -4.57 -0.38 1.14e-5 Diastolic blood pressure; TGCT cis rs8111998 0.826 rs4932775 chr19:22766651 A/G cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs3733585 0.781 rs6449183 chr4:9970691 C/A cg00071950 chr4:10020882 SLC2A9 -0.63 -7.92 -0.58 1.15e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2115630 0.936 rs8033459 chr15:85253258 C/T cg17173187 chr15:85201210 NMB -0.4 -5.02 -0.41 1.78e-6 P wave terminal force; TGCT cis rs1218582 0.741 rs705094 chr1:154917314 G/A cg24250549 chr1:154909240 PMVK 0.61 6.04 0.48 1.63e-8 Prostate cancer; TGCT cis rs950169 0.724 rs11632668 chr15:84948687 T/C cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs10949662 1.000 rs10949662 chr7:157534105 A/G cg14168080 chr7:157504135 PTPRN2 0.39 4.75 0.39 5.6e-6 Intelligence (multi-trait analysis); TGCT cis rs826838 1.000 rs826892 chr12:39100790 T/C cg26384229 chr12:38710491 ALG10B -0.85 -8.1 -0.59 4.39e-13 Heart rate; TGCT cis rs9372253 0.678 rs9372251 chr6:110700656 A/G cg00083206 chr6:110721305 DDO -0.38 -5.56 -0.45 1.59e-7 Platelet distribution width; TGCT cis rs10256972 0.504 rs3735687 chr7:1066297 A/G cg00431813 chr7:1051703 C7orf50 -0.29 -6.33 -0.49 4.13e-9 Longevity;Endometriosis; TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg05457628 chr5:178986728 RUFY1 0.54 6.29 0.49 4.98e-9 Lung cancer; TGCT cis rs7681440 0.835 rs6831847 chr4:90785341 A/G cg10208370 chr4:90758469 SNCA 0.49 4.61 0.38 9.7e-6 Dementia with Lewy bodies; TGCT cis rs2404602 0.672 rs35374222 chr15:77071394 G/T cg22467129 chr15:76604101 ETFA 0.47 4.62 0.38 9.31e-6 Blood metabolite levels; TGCT cis rs116095464 0.558 rs62347683 chr5:230331 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs2798269 0.604 rs2798275 chr13:22159035 T/A cg18095732 chr13:22033692 ZDHHC20 -0.5 -4.45 -0.37 1.88e-5 PR segment; TGCT cis rs6952808 0.531 rs4721441 chr7:2184060 A/G cg22963979 chr7:1858916 MAD1L1 -0.4 -6.23 -0.49 6.81e-9 Bipolar disorder and schizophrenia; TGCT cis rs929354 0.651 rs6951298 chr7:156949149 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs4642101 0.512 rs12629892 chr3:12818920 A/G cg05775895 chr3:12838266 CAND2 0.78 7.72 0.57 3.34e-12 QRS complex (12-leadsum); TGCT cis rs12477438 0.520 rs6743355 chr2:99732360 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs1008375 1.000 rs1860597 chr4:17657650 C/T cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs858239 0.600 rs61292332 chr7:23131862 C/T cg05602783 chr7:23145260 KLHL7 -0.58 -4.85 -0.4 3.68e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs17767294 0.708 rs41269275 chr6:27833315 C/G cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg04234412 chr22:24373322 LOC391322 -0.94 -11.92 -0.73 2.73e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.962 rs4699596 chr4:99012924 C/T cg05340658 chr4:99064831 C4orf37 0.44 4.48 0.37 1.65e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.47 -0.37 1.72e-5 Bipolar disorder; TGCT cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs116095464 0.558 rs10057299 chr5:242135 C/T cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs9549260 0.755 rs2151785 chr13:41243660 G/A cg21288729 chr13:41239152 FOXO1 1.0 10.25 0.68 3.06e-18 Red blood cell count; TGCT cis rs8103278 0.860 rs11669073 chr19:46324880 C/T cg11657440 chr19:46296263 DMWD -0.6 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.5 5.41 0.44 3.18e-7 Lymphocyte counts; TGCT cis rs9467711 0.516 rs523383 chr6:25869848 A/G cg03517284 chr6:25882590 NA -0.76 -5.17 -0.42 9.19e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2982552 0.805 rs2982557 chr6:152056369 G/A cg22157087 chr6:152012887 ESR1 0.21 5.25 0.43 6.29e-7 Bone properties (heel); TGCT cis rs6076065 0.775 rs6083114 chr20:23379528 G/T cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg05785598 chr3:49045655 WDR6 0.36 4.78 0.39 4.78e-6 Menarche (age at onset); TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg22166914 chr1:53195759 ZYG11B 0.36 5.71 0.46 8.05e-8 Monocyte count; TGCT trans rs7726839 0.574 rs12517345 chr5:628294 G/A cg25482853 chr8:67687455 SGK3 1.22 10.53 0.69 6.33e-19 Obesity-related traits; TGCT cis rs4808199 1.000 rs60003758 chr19:19557353 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.7 5.07 0.41 1.41e-6 Nonalcoholic fatty liver disease; TGCT cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs7666738 0.830 rs1426665 chr4:99027764 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.13 0.42 1.1e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs66573146 0.831 rs56300156 chr4:6990813 G/C cg00086871 chr4:6988644 TBC1D14 0.95 4.69 0.39 7.15e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs8017423 0.967 rs11621364 chr14:90709115 A/G cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs2836950 0.509 rs4816618 chr21:40599529 G/A cg06238570 chr21:40685208 BRWD1 -0.6 -6.21 -0.49 7.27e-9 Menarche (age at onset); TGCT cis rs7412746 0.611 rs3768018 chr1:150723747 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.47 0.37 1.77e-5 Melanoma; TGCT cis rs9916302 0.752 rs9901219 chr17:37558369 T/G cg15445000 chr17:37608096 MED1 -0.33 -4.64 -0.38 8.86e-6 Glomerular filtration rate (creatinine); TGCT cis rs7267979 1.000 rs6037086 chr20:25306338 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12500482 1.000 rs12500482 chr4:2430235 A/G cg08330972 chr4:2403930 ZFYVE28 -0.33 -4.54 -0.38 1.34e-5 Cognitive function; TGCT cis rs7246657 0.722 rs2909098 chr19:38204248 G/A cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs4713118 0.955 rs9393847 chr6:27687973 G/A cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT cis rs1215050 0.740 rs13134479 chr4:99067723 G/A cg05340658 chr4:99064831 C4orf37 0.44 5.3 0.43 5.03e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs881375 0.967 rs1548783 chr9:123658639 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.4 4.49 0.37 1.63e-5 Rheumatoid arthritis; TGCT cis rs13401104 0.587 rs62190972 chr2:237145164 T/C cg26422059 chr2:237146110 ASB18 0.57 4.56 0.38 1.19e-5 Educational attainment; TGCT cis rs7119 0.931 rs12901998 chr15:77833524 G/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.7 -0.39 6.77e-6 Type 2 diabetes; TGCT trans rs7613875 0.641 rs6446194 chr3:50067298 T/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs151997 0.569 rs62367393 chr5:50270360 C/A cg06027927 chr5:50259733 NA 0.54 5.44 0.44 2.76e-7 Callous-unemotional behaviour; TGCT cis rs2073300 1.000 rs6048835 chr20:23462343 G/C cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs12579753 1.000 rs12830268 chr12:82233627 A/C cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg22105103 chr4:187893119 NA -0.35 -4.98 -0.41 2.07e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2304069 0.550 rs216144 chr5:149445480 T/C cg05650999 chr5:148883763 CSNK1A1 -0.22 -4.52 -0.38 1.44e-5 HIV-1 control; TGCT cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg06618935 chr21:46677482 NA 0.37 5.59 0.45 1.37e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10514758 0.744 rs72491128 chr3:114910078 G/C cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs7119 0.700 rs7497168 chr15:77886231 A/C cg27398640 chr15:77910606 LINGO1 0.33 6.85 0.52 2.99e-10 Type 2 diabetes; TGCT cis rs514406 0.861 rs35517489 chr1:53304062 G/C cg08859206 chr1:53392774 SCP2 -0.41 -6.13 -0.48 1.05e-8 Monocyte count; TGCT cis rs6429082 0.811 rs291348 chr1:235667690 A/G cg26050004 chr1:235667680 B3GALNT2 0.82 8.69 0.62 1.84e-14 Adiposity; TGCT cis rs7772486 0.774 rs6930181 chr6:146180974 A/T cg23711669 chr6:146136114 FBXO30 -0.77 -7.5 -0.56 1.08e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.659 rs7210700 chr17:56668186 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs7246657 0.943 rs8109632 chr19:37931125 A/T cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs6939532 0.522 rs4712980 chr6:26355758 G/T cg05738196 chr6:26577821 NA 0.5 4.77 0.39 4.98e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2224391 0.784 rs67285271 chr6:5279267 T/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -4.8 -0.4 4.54e-6 Height; TGCT cis rs12142240 0.698 rs67941619 chr1:46838219 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7666738 0.830 rs10009943 chr4:99021475 G/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs911555 0.755 rs8016676 chr14:103904842 C/A cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT trans rs208515 0.525 rs10944870 chr6:66687757 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs7647973 1.000 rs3870339 chr3:49536863 T/A cg07636037 chr3:49044803 WDR6 0.64 5.26 0.43 6.12e-7 Menarche (age at onset); TGCT cis rs2295359 0.892 rs12029362 chr1:67624231 G/A cg12940439 chr1:67600707 NA 0.58 5.9 0.47 3.2e-8 Psoriasis; TGCT cis rs9549367 0.789 rs9577220 chr13:113908294 T/A cg18105134 chr13:113819100 PROZ -0.35 -5.94 -0.47 2.68e-8 Platelet distribution width; TGCT cis rs66573146 1.000 rs56350643 chr4:7017591 G/A cg05069807 chr4:6945702 TBC1D14 0.37 5.2 0.42 8.07e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs2455799 0.634 rs11128765 chr3:15903331 G/T cg16303742 chr3:15540471 COLQ -0.24 -4.59 -0.38 1.07e-5 Mean platelet volume; TGCT cis rs1552244 0.554 rs3846167 chr3:9996426 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.32 -4.84 -0.4 3.76e-6 Alzheimer's disease; TGCT cis rs1577917 0.958 rs6454487 chr6:86446868 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 5.09 0.42 1.32e-6 Response to antipsychotic treatment; TGCT cis rs7674212 0.531 rs4698876 chr4:103933567 T/G cg16532752 chr4:104119610 CENPE -0.6 -5.29 -0.43 5.33e-7 Type 2 diabetes; TGCT cis rs5769765 0.908 rs9616370 chr22:50306316 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.15 11.32 0.71 7.79e-21 Schizophrenia; TGCT cis rs8072100 0.713 rs57427906 chr17:45494014 G/A cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs368755101 1 rs368755101 chr2:100762215 AG/A cg07810366 chr2:100720526 AFF3 -0.37 -5.28 -0.43 5.54e-7 Plateletcrit;Red blood cell count; TGCT cis rs72627509 0.857 rs56155140 chr4:57824451 G/A cg26694713 chr4:57773883 REST 0.72 6.38 0.5 3.21e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7312933 0.558 rs1669886 chr12:42838240 A/G cg19980929 chr12:42632907 YAF2 -0.41 -5.8 -0.46 5.14e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg15691649 chr6:25882328 NA -0.58 -7.44 -0.56 1.43e-11 Urate levels; TGCT cis rs698813 0.572 rs6544749 chr2:44478077 G/A cg00619915 chr2:44497795 NA -0.25 -5.7 -0.46 8.13e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs9788721 0.806 rs951985 chr15:78720923 T/G cg18825076 chr15:78729989 IREB2 -0.33 -5.05 -0.41 1.55e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs7552404 1.000 rs7518038 chr1:76154430 G/A cg10523679 chr1:76189770 ACADM 0.9 9.82 0.66 3.52e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7772486 0.806 rs4075695 chr6:146250959 A/G cg23711669 chr6:146136114 FBXO30 -0.8 -8.9 -0.62 5.72e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs62380364 0.542 rs2457979 chr5:88039660 T/A cg24804195 chr5:87968844 LOC645323 -0.6 -6.05 -0.48 1.59e-8 Intelligence (multi-trait analysis); TGCT cis rs1483890 0.723 rs1483888 chr3:69413329 G/T cg22125112 chr3:69402811 FRMD4B 0.29 4.8 0.4 4.57e-6 Resting heart rate; TGCT cis rs2204008 0.837 rs8189467 chr12:38241956 T/C cg13010199 chr12:38710504 ALG10B 0.6 4.64 0.38 8.72e-6 Bladder cancer; TGCT cis rs7666738 0.830 rs4699590 chr4:98974030 A/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6074578 0.648 rs12624954 chr20:139456 G/A cg16931068 chr20:139680 DEFB127 0.27 4.52 0.38 1.4e-5 Hirschsprung disease; TGCT cis rs7681440 0.845 rs6843084 chr4:90766230 T/C cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs4689388 0.824 rs6446482 chr4:6295693 C/G cg25554036 chr4:6271136 WFS1 0.57 7.87 0.58 1.54e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9733 0.526 rs6587542 chr1:150907701 G/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Tonsillectomy; TGCT cis rs732765 1.000 rs709888 chr14:75369346 T/C cg06637938 chr14:75390232 RPS6KL1 -0.65 -5.51 -0.44 1.99e-7 Non-small cell lung cancer; TGCT trans rs3780486 0.846 rs10113903 chr9:33122645 C/G cg20290983 chr6:43655470 MRPS18A -1.2 -15.17 -0.81 4.92e-30 IgG glycosylation; TGCT cis rs7945705 1.000 rs10840134 chr11:8865363 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.4 4.47 0.37 1.72e-5 Hemoglobin concentration; TGCT cis rs931127 0.624 rs2306364 chr11:65412467 G/A cg27068330 chr11:65405492 SIPA1 -0.96 -10.8 -0.7 1.42e-19 Systemic lupus erythematosus; TGCT cis rs9911578 0.967 rs12938821 chr17:56959422 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs2839186 0.872 rs13052495 chr21:47707474 G/A cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs7224685 0.569 rs12940782 chr17:3992712 T/C cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs7267979 1.000 rs6050547 chr20:25326012 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg11301795 chr4:187892539 NA 0.33 4.79 0.39 4.75e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7655841 0.524 rs189236 chr4:130028412 C/T cg26347359 chr4:129759716 PHF17 -0.45 -6.09 -0.48 1.3e-8 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs367943 0.965 rs463249 chr5:112797430 A/C cg12552261 chr5:112820674 MCC -0.24 -4.89 -0.4 3.04e-6 Type 2 diabetes; TGCT cis rs4494114 1.000 rs9439082 chr1:39344055 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.23 -0.49 6.58e-9 Blood protein levels; TGCT cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg13012494 chr21:47604986 C21orf56 0.37 4.68 0.39 7.49e-6 Testicular germ cell tumor; TGCT cis rs61990749 0.597 rs1008988 chr14:78260795 A/G cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT trans rs10435719 0.764 rs10103485 chr8:11787563 C/T cg15556689 chr8:8085844 FLJ10661 0.78 7.33 0.55 2.63e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs6500602 0.727 rs7193136 chr16:4580034 C/T cg08645402 chr16:4508243 NA 0.19 5.3 0.43 5.14e-7 Schizophrenia; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg10150615 chr22:24372951 LOC391322 -1.0 -12.91 -0.76 1.1e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs16867321 0.671 rs4666665 chr2:181463705 A/G cg23363182 chr2:181467187 NA -0.42 -4.46 -0.37 1.8e-5 Obesity; TGCT cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg18305652 chr10:134549665 INPP5A 0.33 5.86 0.47 3.93e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11190604 1.000 rs3750626 chr10:102266316 C/T cg16342193 chr10:102329863 NA -0.38 -4.89 -0.4 3.06e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs8016982 0.651 rs9806027 chr14:81668707 G/C cg01989461 chr14:81687754 GTF2A1 0.71 6.46 0.5 2.2e-9 Schizophrenia; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg14159672 chr1:205819179 PM20D1 0.61 7.57 0.56 7.33e-12 Menarche (age at onset); TGCT cis rs7819412 0.618 rs34772085 chr8:10964906 C/T cg03192020 chr8:11204681 TDH -0.56 -5.22 -0.42 7.31e-7 Triglycerides; TGCT cis rs7267979 1.000 rs6050626 chr20:25428261 T/C cg16686733 chr20:25566563 NINL 0.58 5.84 0.46 4.39e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs666930 0.967 rs637868 chr1:120257110 A/G cg19096424 chr1:120255104 PHGDH 0.55 5.18 0.42 8.78e-7 Breast cancer; TGCT cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg13683864 chr3:40499215 RPL14 -1.1 -11.83 -0.73 4.49e-22 Renal cell carcinoma; TGCT cis rs6589563 0.609 rs12280724 chr11:116613423 A/C cg15855170 chr11:116574279 NA 0.34 4.54 0.38 1.3e-5 Eosinophil counts; TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs9467711 0.606 rs9379851 chr6:26354780 A/C cg10795676 chr6:26370623 BTN3A2 -0.45 -4.93 -0.4 2.6e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7103648 0.864 rs12801188 chr11:47388214 G/A cg20307385 chr11:47447363 PSMC3 0.99 11.74 0.73 7.18e-22 Diastolic blood pressure;Systolic blood pressure; TGCT trans rs9929218 0.551 rs2274239 chr16:68725783 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.61 7.96 0.58 9.54e-13 Colorectal cancer; TGCT cis rs7666738 0.830 rs6839277 chr4:99015563 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4786125 0.516 rs7203888 chr16:6915483 T/C cg03623568 chr16:6915990 A2BP1 -0.44 -6.63 -0.51 9.34e-10 Heart rate variability traits (SDNN); TGCT trans rs4332037 0.950 rs11767515 chr7:1941051 C/T cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT cis rs11105298 0.891 rs3741898 chr12:89933763 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.85 -0.4 3.63e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2243480 0.901 rs778687 chr7:65835819 G/A cg18252515 chr7:66147081 NA -1.22 -7.33 -0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs2300747 0.932 rs2300746 chr1:117082183 C/G cg26677431 chr1:117075710 CD58 -0.23 -4.56 -0.38 1.23e-5 Primary biliary cholangitis;Multiple sclerosis; TGCT cis rs3796352 1.000 rs9874517 chr3:53128371 A/G cg15956490 chr3:53032818 SFMBT1 0.49 5.58 0.45 1.41e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10883723 0.810 rs7090034 chr10:104281155 C/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4918072 0.637 rs61861138 chr10:105613417 G/A cg11005552 chr10:105648138 OBFC1 0.41 5.16 0.42 9.36e-7 Coronary artery disease; TGCT cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.57 -5.67 -0.45 9.59e-8 Electroencephalogram traits; TGCT cis rs12210905 0.688 rs72841400 chr6:27489911 T/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs1218582 0.803 rs7531728 chr1:154840516 C/A cg06221963 chr1:154839813 KCNN3 -0.78 -14.77 -0.8 4.24e-29 Prostate cancer; TGCT cis rs9372498 0.505 rs17427284 chr6:118991953 A/T cg07617317 chr6:118971624 C6orf204 0.47 4.65 0.39 8.43e-6 Diastolic blood pressure; TGCT cis rs1008375 1.000 rs4235388 chr4:17682030 G/A cg10189774 chr4:17578691 LAP3 0.54 4.97 0.41 2.14e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg00684032 chr4:1343700 KIAA1530 0.21 4.52 0.38 1.44e-5 Obesity-related traits; TGCT cis rs7752195 0.643 rs77006546 chr6:25219582 T/C cg16898833 chr6:26189333 HIST1H4D 1.21 4.7 0.39 6.82e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.800 rs4926930 chr1:53217335 A/G cg01802117 chr1:53393560 SCP2 0.44 5.26 0.43 6.2e-7 Monocyte count; TGCT trans rs2727020 0.729 rs10742932 chr11:49173234 T/C cg03929089 chr4:120376271 NA -0.71 -8.05 -0.59 5.64e-13 Coronary artery disease; TGCT cis rs72615157 0.634 rs74774557 chr7:99810425 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.73 5.55 0.45 1.68e-7 Lung function (FEV1/FVC); TGCT cis rs3772130 0.962 rs11715951 chr3:121522968 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT trans rs8073060 0.586 rs225300 chr17:33922428 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.04 -0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs28386778 0.897 rs894413 chr17:61916347 A/G cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs11030122 0.673 rs10767767 chr11:4003678 C/T cg18678763 chr11:4115507 RRM1 -0.47 -5.68 -0.45 8.88e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs4319547 0.698 rs10773178 chr12:122944752 T/C cg05707623 chr12:122985044 ZCCHC8 -0.63 -4.94 -0.41 2.49e-6 Body mass index; TGCT cis rs8002180 0.959 rs2027445 chr13:95921388 C/T cg24476569 chr13:95954382 ABCC4 0.39 4.97 0.41 2.2e-6 Blood metabolite levels; TGCT cis rs644799 0.582 rs473157 chr11:95596874 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.56 5.96 0.47 2.44e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11098499 0.775 rs10021601 chr4:120282563 G/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs2180341 0.618 rs12210968 chr6:127596985 A/G cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs6951245 0.935 rs118132455 chr7:1068232 C/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT trans rs208520 1.000 rs12192261 chr6:66985268 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs1023500 0.505 rs134874 chr22:42661144 A/G cg05082376 chr22:42548792 NA -0.21 -4.61 -0.38 9.93e-6 Schizophrenia; TGCT cis rs477895 0.713 rs882146 chr11:63976699 G/A cg04317338 chr11:64019027 PLCB3 0.81 6.89 0.53 2.49e-10 Mean platelet volume; TGCT cis rs7000551 0.581 rs11136030 chr8:22254235 C/T cg12081754 chr8:22256438 SLC39A14 0.33 4.77 0.39 5.04e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6684514 1.000 rs10908495 chr1:156263940 T/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs3806843 0.576 rs246017 chr5:140335060 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg16145915 chr7:1198662 ZFAND2A -0.52 -6.44 -0.5 2.34e-9 Longevity;Endometriosis; TGCT cis rs2245008 0.671 rs907036 chr16:83989850 A/T cg27171569 chr16:83987465 OSGIN1 0.56 7.89 0.58 1.35e-12 Pursuit maintenance gain; TGCT cis rs7547997 0.654 rs10158210 chr1:158311985 A/G cg07950803 chr1:158223934 CD1A 0.32 5.08 0.42 1.35e-6 QRS duration; TGCT cis rs7027203 0.576 rs7855940 chr9:96535966 C/G cg13679303 chr9:96623674 NA -0.52 -7.52 -0.56 9.69e-12 DNA methylation (variation); TGCT cis rs4975616 0.804 rs457130 chr5:1336178 A/T cg06550200 chr5:1325588 CLPTM1L -0.31 -4.86 -0.4 3.44e-6 Lung cancer; TGCT cis rs4851266 1.000 rs1122231 chr2:100834546 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.41 -0.44 3.1e-7 Educational attainment; TGCT cis rs1451375 0.698 rs11238226 chr7:50645827 A/G cg18232548 chr7:50535776 DDC 0.46 7.1 0.54 8.31e-11 Malaria; TGCT cis rs76419734 0.558 rs72669984 chr4:106544702 C/T cg24545054 chr4:106630052 GSTCD;INTS12 0.83 4.67 0.39 7.6e-6 Post bronchodilator FEV1; TGCT cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.21 0.49 7.27e-9 Bipolar disorder; TGCT cis rs2692947 0.727 rs1657502 chr2:96795608 A/C cg22654517 chr2:96458247 NA 0.22 5.07 0.41 1.41e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7666738 0.830 rs4440224 chr4:99044924 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs11264213 0.591 rs274755 chr1:36544237 T/C cg27506609 chr1:36549197 TEKT2 -0.49 -5.82 -0.46 4.73e-8 Schizophrenia; TGCT cis rs6964587 0.967 rs1978061 chr7:91779242 G/A cg17063962 chr7:91808500 NA 0.93 10.08 0.67 8.03e-18 Breast cancer; TGCT cis rs1348850 0.874 rs12996447 chr2:178283592 C/T cg22681709 chr2:178499509 PDE11A -0.35 -4.73 -0.39 5.89e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9926296 0.682 rs645019 chr16:89716883 C/T cg21285383 chr16:89894308 SPIRE2 -0.33 -4.64 -0.38 8.56e-6 Vitiligo; TGCT cis rs9818758 0.607 rs34580506 chr3:49113713 C/A cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9443645 0.869 rs4706080 chr6:79760997 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs3924048 0.559 rs4075303 chr1:12626593 C/G cg00291366 chr1:12616550 NA 0.32 5.03 0.41 1.66e-6 Optic cup area; TGCT cis rs9611565 0.512 rs2899347 chr22:42158204 T/C cg03806693 chr22:41940476 POLR3H 1.04 10.57 0.69 5.2e-19 Vitiligo; TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.1 0.42 1.24e-6 Menopause (age at onset); TGCT cis rs11122272 0.735 rs973254 chr1:231521149 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.73 -7.29 -0.55 3.25e-11 Hemoglobin concentration; TGCT cis rs1008375 1.000 rs4698635 chr4:17630242 C/A cg18681998 chr4:17616180 MED28 1.02 11.4 0.72 4.89e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1461503 0.966 rs10790547 chr11:122842110 T/A cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs3803170 0.513 rs10849942 chr12:111818637 T/C cg10833066 chr12:111807467 FAM109A 0.35 5.51 0.44 1.94e-7 Mean corpuscular hemoglobin; TGCT cis rs2439831 0.867 rs2447208 chr15:43933895 C/T cg19166733 chr15:44192098 FRMD5 -0.24 -4.89 -0.4 3.08e-6 Lung cancer in ever smokers; TGCT cis rs9926296 0.712 rs258330 chr16:89729574 T/G cg26513180 chr16:89883248 FANCA -0.67 -6.37 -0.5 3.32e-9 Vitiligo; TGCT cis rs28595532 0.920 rs114057512 chr4:119750179 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg10263370 chr3:44754102 ZNF502 -0.41 -4.94 -0.41 2.47e-6 Depressive symptoms; TGCT cis rs10751667 0.621 rs7396107 chr11:970029 C/T cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs12479064 0.724 rs3792150 chr2:100041849 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.7 -6.28 -0.49 5.1e-9 Chronic sinus infection; TGCT cis rs6840360 0.607 rs1561918 chr4:152446832 T/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.791 rs446362 chr6:145878716 G/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12477438 1.000 rs6542873 chr2:99824965 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -5.73 -0.46 7.13e-8 Chronic sinus infection; TGCT cis rs6089829 0.962 rs4809456 chr20:61660849 C/A cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs9787249 0.874 rs7520588 chr1:40214525 T/A cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs7666738 0.716 rs6814353 chr4:99074202 A/G cg05340658 chr4:99064831 C4orf37 0.51 5.62 0.45 1.18e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9399137 0.507 rs28384513 chr6:135376209 T/G cg24558204 chr6:135376177 HBS1L 0.47 4.73 0.39 5.98e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs204693 0.623 rs204687 chr20:541855 A/G cg15180867 chr20:591076 TCF15 0.65 4.48 0.37 1.69e-5 Pursuit maintenance gain; TGCT cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg10108389 chr3:44770937 ZNF501 -0.48 -4.96 -0.41 2.31e-6 Depressive symptoms; TGCT cis rs669446 0.533 rs2158956 chr1:44211697 T/C cg12908607 chr1:44402522 ARTN -0.63 -7.43 -0.56 1.52e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs362272 0.545 rs3135146 chr4:3307638 C/G cg22655196 chr4:3374909 RGS12 -0.25 -5.02 -0.41 1.73e-6 Serum sulfate level; TGCT cis rs910316 1.000 rs13099 chr14:75599155 G/A cg23033748 chr14:75592666 NEK9 -0.28 -4.76 -0.39 5.33e-6 Height; TGCT cis rs6912958 0.712 rs6454638 chr6:88329427 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.5 4.73 0.39 6.12e-6 Monocyte percentage of white cells; TGCT cis rs916888 0.773 rs538628 chr17:44787313 G/C cg01570182 chr17:44337453 NA 1.08 9.48 0.65 2.25e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4563143 0.704 rs16961809 chr19:29226299 C/T cg03161606 chr19:29218774 NA 0.59 6.5 0.5 1.75e-9 Methadone dose in opioid dependence; TGCT cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.67 -6.86 -0.52 2.92e-10 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs12287396 chr11:49819798 G/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.77 -7.97 -0.58 8.65e-13 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT cis rs4711350 0.862 rs487835 chr6:33710933 G/A cg18005901 chr6:33739558 LEMD2 0.57 5.9 0.47 3.23e-8 Schizophrenia; TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg11494091 chr17:61959527 GH2 0.61 14.9 0.8 2.04e-29 Prudent dietary pattern; TGCT cis rs9436747 0.641 rs11208675 chr1:66045424 T/G cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.65 0.39 8.37e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg00149659 chr3:10157352 C3orf10 0.92 5.57 0.45 1.5e-7 Alzheimer's disease; TGCT cis rs7681440 0.715 rs17016305 chr4:90791381 A/G cg20003494 chr4:90757398 SNCA -0.53 -4.74 -0.39 5.65e-6 Dementia with Lewy bodies; TGCT cis rs875971 1.000 rs6961717 chr7:65587537 C/T cg11764359 chr7:65958608 NA -0.57 -4.99 -0.41 2.02e-6 Aortic root size; TGCT cis rs114540395 0.858 rs78446856 chr10:103119815 T/A cg18276125 chr10:102749041 C10orf2 0.36 4.44 0.37 1.98e-5 Schizophrenia; TGCT cis rs7681440 0.835 rs1899389 chr4:90802998 G/A cg14346243 chr4:90757452 SNCA -0.5 -4.75 -0.39 5.46e-6 Dementia with Lewy bodies; TGCT cis rs7010267 0.669 rs2073617 chr8:119964283 G/A cg17171407 chr8:119960777 TNFRSF11B 0.28 5.16 0.42 9.44e-7 Total body bone mineral density (age 45-60); TGCT cis rs9359856 0.510 rs6937244 chr6:90468465 C/A cg13799429 chr6:90582589 CASP8AP2 0.46 4.78 0.39 4.95e-6 Bipolar disorder; TGCT cis rs694739 1.000 rs694739 chr11:64097233 A/G cg23796481 chr11:64053134 BAD;GPR137 0.68 6.95 0.53 1.88e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs73198271 0.653 rs3827811 chr8:8659038 C/T cg06636001 chr8:8085503 FLJ10661 -0.61 -4.62 -0.38 9.61e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs6938 0.534 rs12913293 chr15:75184458 G/C cg09165964 chr15:75287851 SCAMP5 0.56 5.29 0.43 5.38e-7 Breast cancer; TGCT cis rs12765878 0.627 rs1265166 chr10:105671248 C/A cg11005552 chr10:105648138 OBFC1 -0.4 -6.2 -0.49 7.61e-9 Coronary artery disease; TGCT cis rs9911578 1.000 rs6503887 chr17:56993320 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs17539620 0.624 rs4566892 chr6:154837346 C/T cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs6674176 0.569 rs11210935 chr1:44369444 G/A cg12908607 chr1:44402522 ARTN -0.68 -7.81 -0.57 2.09e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9527 0.590 rs7067663 chr10:104883650 A/G cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs4478037 0.558 rs72854780 chr3:33072557 C/T cg19404215 chr3:33155277 CRTAP 0.99 4.98 0.41 2.08e-6 Major depressive disorder; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg08736216 chr1:53307985 ZYG11A -0.29 -5.9 -0.47 3.29e-8 Monocyte count; TGCT trans rs3780486 0.505 rs10813958 chr9:33165985 A/G cg20290983 chr6:43655470 MRPS18A 0.78 8.52 0.61 4.46e-14 IgG glycosylation; TGCT cis rs4237845 0.780 rs3751331 chr12:58290278 G/A cg23860436 chr12:58378763 NA 0.35 4.92 0.4 2.7e-6 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.510 rs4841524 chr8:11243126 C/G cg21775007 chr8:11205619 TDH -0.67 -6.58 -0.51 1.17e-9 Retinal vascular caliber; TGCT cis rs7674212 0.570 rs2251634 chr4:104082349 C/T cg16532752 chr4:104119610 CENPE -0.61 -5.67 -0.45 9.45e-8 Type 2 diabetes; TGCT cis rs9942416 0.660 rs34905687 chr5:74997736 A/G cg02573091 chr5:74908125 NA 0.39 4.6 0.38 1.03e-5 Age-related disease endophenotypes; TGCT cis rs17376456 0.569 rs10076965 chr5:93094972 G/A cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT cis rs2997447 0.761 rs55960411 chr1:26437741 G/C cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs6693567 0.545 rs1566225 chr1:150415990 G/C cg09579323 chr1:150459698 TARS2 0.52 4.62 0.38 9.56e-6 Migraine; TGCT cis rs6582630 0.555 rs56228141 chr12:38518652 T/G cg13010199 chr12:38710504 ALG10B 0.59 4.77 0.39 5.14e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7655441 1.000 rs11098965 chr4:80888040 C/T cg02241357 chr4:80885279 ANTXR2 -0.23 -4.52 -0.38 1.45e-5 Neutrophil percentage of white cells; TGCT cis rs6840360 0.642 rs2709831 chr4:152379651 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs763014 0.966 rs4144003 chr16:645968 C/T cg27436995 chr16:743998 FBXL16 -0.46 -4.97 -0.41 2.17e-6 Height; TGCT cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs2288073 1.000 rs2288073 chr2:24413298 C/T cg02683114 chr2:24398427 C2orf84 0.26 5.98 0.47 2.2e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs2836950 0.565 rs2836942 chr21:40591381 A/G cg17971929 chr21:40555470 PSMG1 -0.51 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg09177884 chr7:1199841 ZFAND2A -0.6 -6.31 -0.49 4.58e-9 Longevity;Endometriosis; TGCT cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg07424592 chr7:64974309 NA 1.35 7.66 0.57 4.49e-12 Diabetic kidney disease; TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg05457628 chr5:178986728 RUFY1 -0.53 -6.09 -0.48 1.34e-8 Lung cancer; TGCT cis rs59107033 0.607 rs56156664 chr3:123118720 T/C cg04890266 chr3:123102914 ADCY5 -0.37 -5.12 -0.42 1.13e-6 Lymphocyte counts; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs7586879 0.593 rs11689546 chr2:25130451 A/G cg01884057 chr2:25150051 NA 0.35 6.87 0.53 2.76e-10 Body mass index; TGCT cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs7714584 1.000 rs4958848 chr5:150271122 G/C cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs4727027 0.800 rs12530946 chr7:148887942 A/G cg23583168 chr7:148888333 NA -0.82 -11.32 -0.71 7.58e-21 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs751984 0.636 rs11607904 chr11:61263029 A/C cg03305746 chr2:106927199 NA -0.58 -7.01 -0.53 1.32e-10 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs1008375 0.966 rs10939736 chr4:17581617 T/A cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.638 rs7793569 chr7:66116633 T/G cg00343986 chr7:65444356 GUSB -0.23 -5.13 -0.42 1.07e-6 Aortic root size; TGCT cis rs9393692 0.846 rs7771202 chr6:26279907 A/G cg13736514 chr6:26305472 NA -0.41 -5.77 -0.46 6.09e-8 Educational attainment; TGCT cis rs1801251 0.963 rs66549961 chr2:233602293 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.5 0.5 1.78e-9 Coronary artery disease; TGCT cis rs5762813 0.524 rs5752815 chr22:29230733 C/A cg02153584 chr22:29168773 CCDC117 0.78 5.31 0.43 4.91e-7 Hematocrit;Hemoglobin concentration; TGCT cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs655029 0.714 rs649729 chr2:31464385 A/T cg14018959 chr2:31480232 EHD3 0.32 4.51 0.38 1.5e-5 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs6125597 0.904 rs2273146 chr20:47839653 C/T cg11220565 chr20:47934802 NA -0.3 -4.58 -0.38 1.13e-5 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs12173015 chr5:269967 A/C cg22857025 chr5:266934 NA 0.3 6.35 0.5 3.76e-9 Breast cancer; TGCT cis rs1532993 0.518 rs9993179 chr4:98634314 A/G cg05340658 chr4:99064831 C4orf37 0.41 4.94 0.41 2.49e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9372498 0.536 rs9489394 chr6:118758234 T/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs1580019 0.961 rs2392056 chr7:32498953 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.66 0.57 4.58e-12 Cognitive ability; TGCT cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg13409248 chr3:40428643 ENTPD3 -0.61 -4.99 -0.41 2.01e-6 Renal cell carcinoma; TGCT cis rs7120118 0.517 rs56825896 chr11:47326184 A/G cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.26e-7 HDL cholesterol; TGCT trans rs7248779 0.512 rs7250002 chr19:2413188 A/G cg25835954 chr13:50160062 RCBTB1 0.76 6.88 0.53 2.6200000000000003e-10 Cortisol levels (saliva); TGCT cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg06238570 chr21:40685208 BRWD1 -0.82 -8.78 -0.62 1.11e-14 Cognitive function; TGCT cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg05738196 chr6:26577821 NA -0.83 -10.61 -0.69 4.07e-19 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.765 rs1722003 chr11:49895896 G/A cg11707556 chr5:10655725 ANKRD33B -0.39 -7.59 -0.56 6.59e-12 Height; TGCT cis rs6121246 0.567 rs6060262 chr20:30193071 A/C cg18721089 chr20:30220636 NA -0.57 -6.22 -0.49 6.83e-9 Mean corpuscular hemoglobin; TGCT cis rs763121 0.853 rs4821810 chr22:39072098 C/G cg06022373 chr22:39101656 GTPBP1 0.8 8.25 0.6 1.95e-13 Menopause (age at onset); TGCT cis rs7267979 0.727 rs2474765 chr20:25245950 G/T cg03522245 chr20:25566470 NINL 0.52 5.4 0.44 3.22e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.68 -7.06 -0.54 1.03e-10 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.554 rs35126802 chr7:1134842 C/T cg09177884 chr7:1199841 ZFAND2A -0.72 -5.71 -0.46 7.86e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7439150 0.954 rs72679195 chr4:155473386 A/G cg22130008 chr4:155548532 NA -0.43 -5.38 -0.44 3.5e-7 Fibrinogen levels; TGCT cis rs6121246 0.567 rs6087700 chr20:30217560 A/G cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs904251 0.523 rs9366935 chr6:37480404 C/T cg08126542 chr6:37504118 NA -0.46 -6.46 -0.5 2.11e-9 Cognitive performance; TGCT cis rs797680 0.822 rs7541304 chr1:93757838 T/A cg17826107 chr1:92977322 EVI5 0.23 5.11 0.42 1.2e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2997447 0.601 rs61776580 chr1:26432719 C/T cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT cis rs2120019 1.000 rs8036197 chr15:75370232 T/C cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT cis rs9611519 0.780 rs5751072 chr22:41656509 C/T cg03806693 chr22:41940476 POLR3H -0.76 -7.37 -0.55 2.05e-11 Neuroticism; TGCT cis rs3540 0.513 rs2589957 chr15:90903311 A/G cg22089800 chr15:90895588 ZNF774 0.82 9.06 0.63 2.29e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs854765 0.547 rs2955372 chr17:17970229 T/C cg04398451 chr17:18023971 MYO15A 0.34 5.46 0.44 2.48e-7 Total body bone mineral density; TGCT cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg18252515 chr7:66147081 NA -1.24 -8.13 -0.59 3.76e-13 Diabetic kidney disease; TGCT cis rs61332075 0.531 rs11885695 chr2:239338632 G/A cg18131467 chr2:239335373 ASB1 -0.84 -5.8 -0.46 5.07e-8 Lung function (FEV1/FVC); TGCT cis rs3847687 1.000 rs3847687 chr12:131525053 C/T cg25772418 chr12:131519998 GPR133 -0.33 -6.1 -0.48 1.26e-8 Longevity; TGCT cis rs1008375 0.932 rs9291660 chr4:17663414 A/G cg10189774 chr4:17578691 LAP3 0.53 4.62 0.38 9.31e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7100689 0.646 rs10736346 chr10:82134281 A/C cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs896854 0.517 rs896851 chr8:95950251 T/C cg09323728 chr8:95962352 TP53INP1 -0.43 -4.9 -0.4 2.98e-6 Type 2 diabetes; TGCT cis rs7582180 0.627 rs2241811 chr2:101011724 C/T cg08017756 chr2:100939284 LONRF2 -0.31 -5.01 -0.41 1.86e-6 Intelligence (multi-trait analysis); TGCT cis rs4294134 0.608 rs12707239 chr7:135247183 C/T cg08396481 chr7:135194601 CNOT4 -0.58 -4.68 -0.39 7.53e-6 Paget's disease; TGCT cis rs13256369 0.802 rs34762800 chr8:8559294 G/A cg17143192 chr8:8559678 CLDN23 0.54 4.86 0.4 3.53e-6 Obesity-related traits; TGCT cis rs12134245 0.747 rs35654098 chr1:92001452 T/A cg07090678 chr1:91966139 CDC7 0.35 4.75 0.39 5.58e-6 Breast cancer; TGCT cis rs4622507 0.773 rs62034614 chr16:55046548 A/G cg04853843 chr16:55358461 IRX6 -0.57 -4.95 -0.41 2.4e-6 Social communication problems; TGCT cis rs3733585 0.631 rs4697707 chr4:10119787 G/T cg00071950 chr4:10020882 SLC2A9 -0.51 -5.28 -0.43 5.7e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7647973 0.626 rs9824435 chr3:49674343 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 -0.39 -5.13 -0.42 1.1e-6 Menarche (age at onset); TGCT cis rs7178572 0.633 rs12900004 chr15:77844904 A/G cg22256960 chr15:77711686 NA -0.82 -7.48 -0.56 1.19e-11 Type 2 diabetes; TGCT cis rs4819052 0.807 rs28715237 chr21:46673768 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs478304 0.651 rs11604451 chr11:65551710 C/T cg27068330 chr11:65405492 SIPA1 -0.95 -9.42 -0.65 3.19e-16 Acne (severe); TGCT cis rs8072100 0.934 rs8067286 chr17:45594590 A/G cg08085267 chr17:45401833 C17orf57 0.48 5.3 0.43 5.03e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs6504663 1.000 rs6504661 chr17:48580126 A/T cg03168497 chr17:48586147 MYCBPAP -0.62 -7.07 -0.54 9.84e-11 Visceral fat; TGCT cis rs2067615 0.524 rs1922436 chr12:107065258 A/G cg15890332 chr12:107067104 RFX4 0.3 5.88 0.47 3.6e-8 Heart rate; TGCT cis rs2204008 0.748 rs7312204 chr12:38334909 T/C cg26384229 chr12:38710491 ALG10B 0.76 6.89 0.53 2.46e-10 Bladder cancer; TGCT cis rs1008375 0.932 rs6449317 chr4:17631253 T/C cg10189774 chr4:17578691 LAP3 0.6 5.08 0.42 1.33e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17197710 0.673 rs41301449 chr11:47303821 C/T cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17374749 0.916 rs9855601 chr3:136768482 T/C cg21827317 chr3:136751795 NA -0.52 -7.56 -0.56 7.86e-12 Anxiety in major depressive disorder; TGCT cis rs7681440 0.904 rs1372521 chr4:90765223 G/A cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs793571 0.543 rs11854073 chr15:58972995 G/A cg05156742 chr15:59063176 FAM63B 0.48 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs2576037 0.623 rs2576042 chr18:44577461 T/C cg23302884 chr18:44338147 ST8SIA5 0.39 4.55 0.38 1.28e-5 Personality dimensions; TGCT cis rs9322193 0.923 rs10747276 chr6:150079875 G/A cg13206674 chr6:150067644 NUP43 0.53 4.65 0.39 8.3e-6 Lung cancer; TGCT cis rs9926296 0.712 rs459920 chr16:89730827 T/C cg03388025 chr16:89894329 SPIRE2 -0.36 -5.33 -0.43 4.49e-7 Vitiligo; TGCT cis rs2580764 0.565 rs7562292 chr2:55230219 C/T cg09592903 chr2:55203963 RTN4 -0.25 -5.45 -0.44 2.58e-7 Mean platelet volume; TGCT cis rs9532580 0.620 rs2755210 chr13:41141282 C/G cg21288729 chr13:41239152 FOXO1 0.92 7.73 0.57 3.14e-12 Mean corpuscular hemoglobin; TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg24675658 chr1:53192096 ZYG11B -0.7 -7.91 -0.58 1.22e-12 Monocyte count; TGCT cis rs4665809 1.000 rs12475854 chr2:26267375 G/A cg04944784 chr2:26401820 FAM59B -0.67 -5.98 -0.47 2.23e-8 Gut microbiome composition (summer); TGCT cis rs2456568 0.900 rs2511399 chr11:93682156 C/T cg14065697 chr11:93583672 C11orf90 0.37 4.62 0.38 9.53e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg14827481 chr10:134361889 INPP5A 0.31 5.03 0.41 1.71e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs66573146 0.831 rs66645969 chr4:6985614 G/A cg05069807 chr4:6945702 TBC1D14 0.32 5.01 0.41 1.83e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7647973 1.000 rs4241407 chr3:49600319 C/T cg06212747 chr3:49208901 KLHDC8B 0.54 4.45 0.37 1.87e-5 Menarche (age at onset); TGCT cis rs6752107 1.000 rs3792112 chr2:234176609 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.8 0.4 4.57e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4478858 0.647 rs1007013 chr1:31710270 C/T cg00250761 chr1:31883323 NA -0.28 -4.92 -0.4 2.66e-6 Alcohol dependence; TGCT cis rs3008870 1.000 rs2755256 chr1:67471692 A/T cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2629540 0.765 rs11245387 chr10:126537825 C/T cg08799069 chr10:126477246 METTL10 -0.28 -4.6 -0.38 1.04e-5 Cocaine dependence; TGCT cis rs12900413 0.562 rs28557101 chr15:90298149 C/T cg24249390 chr15:90295951 MESP1 -0.29 -5.11 -0.42 1.19e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg25703541 chr22:24373054 LOC391322 0.81 6.9 0.53 2.34e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs910316 0.967 rs4899545 chr14:75568138 A/G cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs6964587 0.839 rs2049314 chr7:91464134 C/T cg17063962 chr7:91808500 NA 0.81 8.39 0.6 9.37e-14 Breast cancer; TGCT cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs9787249 0.957 rs12086750 chr1:40210468 G/C cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs61990749 0.597 rs2267758 chr14:78147429 T/C cg02301378 chr14:78227641 SNW1;C14orf178 -0.6 -4.45 -0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg06634786 chr22:41940651 POLR3H -0.84 -7.98 -0.58 8.5e-13 Vitiligo; TGCT cis rs1059312 0.808 rs12831705 chr12:129294905 G/A cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs2834081 0.536 rs11702285 chr21:34474294 G/A cg00274965 chr21:34405681 NA 0.49 4.51 0.38 1.5e-5 Sum eosinophil basophil counts; TGCT cis rs2594989 0.943 rs2442769 chr3:11491086 A/G cg26283222 chr3:11613257 VGLL4 0.22 4.48 0.37 1.68e-5 Circulating chemerin levels; TGCT cis rs6089584 1.000 rs3787424 chr20:60559219 G/A cg13770153 chr20:60521292 NA -0.44 -5.62 -0.45 1.21e-7 Body mass index; TGCT cis rs7666738 0.791 rs6840669 chr4:99016020 G/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 1.000 rs4919471 chr10:102299239 A/G cg16342193 chr10:102329863 NA -0.44 -5.04 -0.41 1.58e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28595532 0.920 rs116834347 chr4:119774155 C/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs1476679 0.830 rs6971558 chr7:100079857 A/T cg13334819 chr7:99746414 C7orf59 0.56 4.53 0.38 1.35e-5 Alzheimer's disease (late onset); TGCT trans rs7615952 0.800 rs12489350 chr3:125644116 T/C cg07211511 chr3:129823064 LOC729375 -0.48 -7.98 -0.58 8.36e-13 Blood pressure (smoking interaction); TGCT cis rs6121246 0.697 rs45557936 chr20:30226690 G/A cg21427119 chr20:30132790 HM13 -0.37 -5.19 -0.42 8.51e-7 Mean corpuscular hemoglobin; TGCT cis rs7000551 0.715 rs1530874 chr8:22347777 G/C cg12081754 chr8:22256438 SLC39A14 0.28 4.69 0.39 7.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6430585 0.583 rs4988163 chr2:136628121 G/T cg07169764 chr2:136633963 MCM6 1.22 10.62 0.69 3.95e-19 Corneal structure; TGCT cis rs28595532 1.000 rs114039398 chr4:119631627 T/C cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs4906332 1.000 rs3783400 chr14:103967045 G/A cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs12477438 0.765 rs4851183 chr2:99629149 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs7192750 0.586 rs4788449 chr16:71931219 G/A cg06353428 chr16:71660113 MARVELD3 0.8 7.2 0.54 5.05e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg06212747 chr3:49208901 KLHDC8B 0.71 6.56 0.51 1.32e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs1008375 1.000 rs2159584 chr4:17620568 G/A cg16339924 chr4:17578868 LAP3 0.63 5.13 0.42 1.07e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs5769707 0.568 rs2011097 chr22:50018069 A/G cg06623630 chr22:50017776 C22orf34 -0.27 -4.64 -0.38 8.67e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs11098499 0.532 rs12512646 chr4:120585733 G/A cg09307838 chr4:120376055 NA 0.59 5.6 0.45 1.31e-7 Corneal astigmatism; TGCT cis rs10791097 0.694 rs2155750 chr11:130751261 A/C cg14779329 chr11:130786720 SNX19 0.29 5.01 0.41 1.85e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs17221829 0.733 rs1844199 chr11:89376368 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg13393036 chr8:95962371 TP53INP1 -0.52 -6.58 -0.51 1.21e-9 Type 2 diabetes; TGCT cis rs4851266 1.000 rs13013169 chr2:100814087 A/C cg07810366 chr2:100720526 AFF3 -0.41 -5.79 -0.46 5.35e-8 Educational attainment; TGCT cis rs9611565 0.729 rs203320 chr22:41913477 T/C cg06481639 chr22:41940642 POLR3H -0.57 -5.17 -0.42 9.14e-7 Vitiligo; TGCT cis rs589448 0.902 rs315124 chr12:69771727 G/A cg11871910 chr12:69753446 YEATS4 0.89 10.53 0.69 6.39e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs9653442 0.545 rs12987209 chr2:100761148 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.31 -0.43 4.89e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9650657 0.524 rs11787278 chr8:10492611 G/C cg27411982 chr8:10470053 RP1L1 0.21 4.69 0.39 7.21e-6 Neuroticism; TGCT cis rs7666738 0.830 rs34892904 chr4:98938097 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10193935 0.786 rs13399052 chr2:42385151 G/A cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.513 rs1596446 chr12:38282160 C/T cg26384229 chr12:38710491 ALG10B -0.84 -7.33 -0.55 2.58e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs11719291 0.833 rs13074318 chr3:48816725 C/T cg00383909 chr3:49044727 WDR6 1.3 6.72 0.52 5.98e-10 Cognitive function; TGCT cis rs7666738 0.606 rs6839946 chr4:99076132 A/C cg05340658 chr4:99064831 C4orf37 0.46 4.99 0.41 2.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10392 0.516 rs4141892 chr20:37590758 T/C cg27552599 chr20:37590471 DHX35 0.38 4.79 0.39 4.77e-6 Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis; TGCT cis rs854765 0.575 rs2955357 chr17:17946401 T/C cg09796270 chr17:17721594 SREBF1 -0.26 -5.17 -0.42 8.95e-7 Total body bone mineral density; TGCT cis rs9303401 0.659 rs12944971 chr17:56988801 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.68 6.48 0.5 1.94e-9 Cognitive test performance; TGCT cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs2120019 1.000 rs8036197 chr15:75370232 T/C cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs9467711 0.651 rs34043431 chr6:25875084 T/C cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs2797160 1.000 rs1777194 chr6:126004883 G/A cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs9527 0.590 rs7912517 chr10:104905529 G/A cg15744005 chr10:104629667 AS3MT -0.4 -4.63 -0.38 9.04e-6 Arsenic metabolism; TGCT cis rs7927592 0.546 rs638076 chr11:68202580 A/G cg16797656 chr11:68205561 LRP5 0.28 5.11 0.42 1.16e-6 Total body bone mineral density; TGCT cis rs3892630 0.878 rs66788054 chr19:33190146 G/T cg22980127 chr19:33182716 NUDT19 0.7 5.18 0.42 8.9e-7 Red blood cell traits; TGCT cis rs12291225 0.679 rs4756786 chr11:14285900 C/A cg19336497 chr11:14380999 RRAS2 -0.39 -6.09 -0.48 1.31e-8 Sense of smell; TGCT cis rs1865760 0.534 rs2032444 chr6:26046744 T/G cg16482183 chr6:26056742 HIST1H1C 0.68 5.61 0.45 1.24e-7 Height; TGCT cis rs4455778 0.536 rs887451 chr7:48943352 T/C cg26309511 chr7:48887640 NA -0.46 -5.51 -0.44 1.98e-7 Lung cancer in never smokers; TGCT cis rs7226408 0.857 rs56822468 chr18:34448917 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7582180 0.629 rs12621892 chr2:100947124 G/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.29e-6 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.04 6.35 0.5 3.65e-9 Gut microbiome composition (summer); TGCT cis rs7095607 1.000 rs12415303 chr10:69964141 C/T cg18986048 chr10:69913749 MYPN 0.45 4.89 0.4 3.07e-6 Lung function (FVC); TGCT cis rs3008870 1.000 rs1925411 chr1:67370292 C/T cg11518657 chr1:67396239 MIER1 0.53 4.72 0.39 6.16e-6 Lymphocyte percentage of white cells; TGCT cis rs9467711 0.790 rs34107459 chr6:26328353 T/C cg05948654 chr6:25930507 SLC17A2 0.36 4.68 0.39 7.48e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs826838 0.967 rs1719856 chr12:39127201 C/T cg13010199 chr12:38710504 ALG10B -0.63 -5.04 -0.41 1.6e-6 Heart rate; TGCT cis rs4665809 1.000 rs1550382 chr2:26266877 T/G cg04944784 chr2:26401820 FAM59B -0.68 -6.07 -0.48 1.45e-8 Gut microbiome composition (summer); TGCT cis rs9911578 1.000 rs11079365 chr17:56945430 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs6089584 0.889 rs6142923 chr20:60596617 C/T cg13770153 chr20:60521292 NA 0.52 6.68 0.51 7.32e-10 Body mass index; TGCT cis rs250677 0.652 rs168751 chr5:148438264 C/T cg18129178 chr5:148520854 ABLIM3 -0.42 -5.74 -0.46 6.77e-8 Breast cancer; TGCT cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg13257436 chr8:145726034 PPP1R16A 0.34 5.47 0.44 2.43e-7 Age at first birth; TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs9486715 0.867 rs1127175 chr6:96999725 C/T cg18709589 chr6:96969512 KIAA0776 -0.8 -7.35 -0.55 2.35e-11 Headache; TGCT cis rs7666738 0.830 rs1120708 chr4:98931260 G/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs11874712 0.899 rs11872954 chr18:43686450 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.15 0.42 1.01e-6 Migraine - clinic-based; TGCT cis rs12681287 0.927 rs7003059 chr8:87330713 C/T cg27223183 chr8:87520930 FAM82B -0.88 -6.82 -0.52 3.62e-10 Caudate activity during reward; TGCT cis rs933688 1.000 rs10474353 chr5:90732285 A/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 9.6 0.65 1.2e-16 Smoking behavior; TGCT cis rs7772486 0.875 rs969694 chr6:146394655 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.97 0.41 2.21e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg13342137 chr4:2252803 MXD4 0.17 4.47 0.37 1.71e-5 Obesity-related traits; TGCT cis rs265548 0.646 rs36689 chr19:17910639 A/G cg16744531 chr19:17905626 B3GNT3 0.42 5.34 0.43 4.26e-7 Tumor biomarkers; TGCT cis rs2439831 0.764 rs12324584 chr15:43683446 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.88 6.11 0.48 1.19e-8 Lung cancer in ever smokers; TGCT cis rs921968 0.643 rs832799 chr2:219490111 C/A cg02176678 chr2:219576539 TTLL4 0.43 6.11 0.48 1.19e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg06035815 chr6:26189597 HIST1H4D 0.44 4.53 0.38 1.39e-5 Schizophrenia; TGCT cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg03806693 chr22:41940476 POLR3H 1.14 12.91 0.76 1.07e-24 Vitiligo; TGCT cis rs7809950 1.000 rs2712189 chr7:107195747 G/A cg23024343 chr7:107201750 COG5 -0.34 -5.16 -0.42 9.35e-7 Coronary artery disease; TGCT cis rs4665809 1.000 rs6729080 chr2:26301282 G/A cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs17030434 0.784 rs72617459 chr4:154661686 T/C cg14289246 chr4:154710475 SFRP2 -0.85 -7.27 -0.55 3.6e-11 Electrocardiographic conduction measures; TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg21237687 chr17:6899380 ALOX12 -0.52 -5.88 -0.47 3.54e-8 Tonsillectomy; TGCT trans rs1814175 0.650 rs6486000 chr11:49659090 T/A cg11707556 chr5:10655725 ANKRD33B -0.43 -10.19 -0.68 4.28e-18 Height; TGCT cis rs6089829 0.962 rs6089825 chr20:61668447 C/T cg08045932 chr20:61659980 NA 0.48 9.01 0.63 3.09e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs7095607 0.560 rs2673794 chr10:69926097 T/C cg18986048 chr10:69913749 MYPN 0.54 5.83 0.46 4.48e-8 Lung function (FVC); TGCT trans rs7819412 0.806 rs2409689 chr8:10932868 A/G cg15556689 chr8:8085844 FLJ10661 -0.84 -8.16 -0.59 3.19e-13 Triglycerides; TGCT trans rs1496653 0.602 rs13060251 chr3:23337221 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs28595532 0.920 rs115994609 chr4:119777273 G/A cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs62318504 chr4:98935558 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs751728 0.931 rs2296746 chr6:33744711 C/T cg00334056 chr6:33755658 LEMD2 -0.25 -4.59 -0.38 1.08e-5 Crohn's disease; TGCT cis rs265548 0.586 rs265542 chr19:17904388 T/G cg21960279 chr19:17905606 B3GNT3 0.49 5.48 0.44 2.3e-7 Tumor biomarkers; TGCT cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg06634786 chr22:41940651 POLR3H -0.7 -6.54 -0.51 1.42e-9 Vitiligo; TGCT cis rs910316 0.967 rs4384542 chr14:75658013 A/C cg08847533 chr14:75593920 NEK9 -0.94 -10.1 -0.67 7.14e-18 Height; TGCT cis rs735396 0.731 rs1182933 chr12:121454622 C/T cg02403541 chr12:121454288 C12orf43 0.77 7.58 0.56 6.97e-12 N-glycan levels; TGCT cis rs7267979 1.000 rs2297497 chr20:25297909 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467603 1.000 rs9467609 chr6:25809751 A/G cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs589448 0.902 rs315131 chr12:69761839 T/G cg11871910 chr12:69753446 YEATS4 0.88 10.41 0.68 1.28e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs9467773 1.000 rs9393729 chr6:26514166 C/T cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.67 0.66 8.18e-17 Cognitive function; TGCT cis rs477895 0.639 rs35858916 chr11:63950529 T/G cg23719950 chr11:63933701 MACROD1 -0.71 -5.87 -0.47 3.72e-8 Mean platelet volume; TGCT cis rs597539 0.652 rs513615 chr11:68705504 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.82 7.31 0.55 2.82e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2980439 0.870 rs2945230 chr8:8109936 A/G cg08975724 chr8:8085496 FLJ10661 0.66 5.99 0.47 2.09e-8 Neuroticism; TGCT cis rs2675662 0.525 rs12264025 chr10:75494450 A/G cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Psoriasis vulgaris;Psoriasis; TGCT cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg00080972 chr5:178986291 RUFY1 0.47 5.51 0.44 2.02e-7 Lung cancer; TGCT trans rs941408 1.000 rs2260416 chr19:2796355 G/A cg19676328 chr12:49525230 TUBA1B -0.74 -7.15 -0.54 6.67e-11 Total cholesterol levels; TGCT cis rs3820068 0.581 rs58567918 chr1:15925823 A/G cg05660106 chr1:15850417 CASP9 0.76 7.33 0.55 2.56e-11 Systolic blood pressure; TGCT cis rs1421811 0.606 rs981001 chr5:32721545 G/A cg16267343 chr5:32710456 NPR3 0.82 6.98 0.53 1.61e-10 Blood pressure; TGCT cis rs10411936 0.924 rs8110761 chr19:16501005 A/G cg19006008 chr19:16999768 F2RL3 0.27 4.84 0.4 3.85e-6 White blood cell count;Multiple sclerosis; TGCT cis rs950880 0.560 rs1558622 chr2:102930147 G/A cg09003973 chr2:102972529 NA -0.51 -4.49 -0.37 1.59e-5 Serum protein levels (sST2); TGCT cis rs9291683 0.609 rs3796836 chr4:10011345 A/G cg11266682 chr4:10021025 SLC2A9 0.69 9.99 0.67 1.34e-17 Bone mineral density; TGCT cis rs8056742 0.730 rs11644038 chr16:85097945 T/G cg00229868 chr16:85520891 NA 0.38 4.77 0.39 5.03e-6 Amyotrophic lateral sclerosis; TGCT cis rs9393777 0.513 rs61240102 chr6:27124904 G/C cg16898833 chr6:26189333 HIST1H4D 0.74 4.48 0.37 1.71e-5 Intelligence (multi-trait analysis); TGCT trans rs2688482 0.512 rs3103953 chr3:195520597 G/A cg17952111 chr19:54960355 LENG8 -0.81 -6.68 -0.51 7.14e-10 Lung disease severity in cystic fibrosis; TGCT cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.6e-6 Menopause (age at onset); TGCT cis rs7666738 0.785 rs11097614 chr4:99092175 G/C cg17366294 chr4:99064904 C4orf37 0.71 5.48 0.44 2.27e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1971762 0.762 rs7976793 chr12:54073069 G/T cg16917193 chr12:54089295 NA 0.6 4.81 0.4 4.22e-6 Height; TGCT cis rs208520 0.690 rs12202913 chr6:66734198 C/T cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs7216064 0.906 rs8074644 chr17:65878217 G/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7439150 1.000 rs72681211 chr4:155479261 T/A cg22130008 chr4:155548532 NA -0.44 -5.59 -0.45 1.36e-7 Fibrinogen levels; TGCT cis rs6901250 0.655 rs636252 chr6:117157774 A/G cg12892004 chr6:117198278 RFX6 -0.41 -5.11 -0.42 1.2e-6 C-reactive protein levels; TGCT cis rs7267979 1.000 rs3002702 chr20:25268920 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11971779 0.680 rs4077889 chr7:139033914 A/G cg07862535 chr7:139043722 LUC7L2 0.56 4.46 0.37 1.82e-5 Diisocyanate-induced asthma; TGCT cis rs12510870 0.599 rs28612539 chr4:74450728 A/G cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg03303774 chr4:1407052 NA 0.34 5.43 0.44 2.91e-7 Obesity-related traits; TGCT cis rs10858047 0.941 rs116185978 chr1:115118982 C/T cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs1838472 0.607 rs9880957 chr3:123979651 C/T cg19008133 chr3:123124015 ADCY5 0.18 4.58 0.38 1.12e-5 Schizophrenia; TGCT cis rs7666738 0.830 rs4699597 chr4:99019031 G/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2797780 1.000 rs2797780 chr6:37506415 T/C cg00985040 chr6:37553208 NA 0.24 4.77 0.39 5.04e-6 Systemic lupus erythematosus; TGCT cis rs7399018 0.643 rs6580810 chr12:51610478 C/T cg25754956 chr12:51612065 POU6F1 0.94 8.81 0.62 9.47e-15 Cisplatin-induced ototoxicity; TGCT cis rs875971 1.000 rs6946143 chr7:65579722 A/C cg11764359 chr7:65958608 NA 0.58 5.49 0.44 2.2e-7 Aortic root size; TGCT trans rs2727020 0.729 rs2299650 chr11:49174007 A/C cg03929089 chr4:120376271 NA -0.7 -8.1 -0.59 4.3e-13 Coronary artery disease; TGCT cis rs7267979 0.844 rs2257649 chr20:25263457 T/G cg14121845 chr20:25566513 NINL 0.45 4.6 0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2115536 0.967 rs934137 chr15:80211768 T/C cg00225070 chr15:80189496 MTHFS 0.58 5.01 0.41 1.8e-6 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs968567 0.539 rs174556 chr11:61580635 C/T cg19610905 chr11:61596333 FADS2 -1.05 -11.51 -0.72 2.6e-21 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs12497850 0.931 rs3774628 chr3:48801840 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.52 -0.44 1.89e-7 Parkinson's disease; TGCT cis rs6674176 0.628 rs3791119 chr1:44431362 C/G cg12908607 chr1:44402522 ARTN -0.67 -8.15 -0.59 3.4e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs453301 0.522 rs1964356 chr8:8853270 G/T cg15556689 chr8:8085844 FLJ10661 0.69 6.25 0.49 6.13e-9 Joint mobility (Beighton score); TGCT cis rs10501293 1.000 rs10768913 chr11:43060750 T/C cg03447554 chr11:43094025 NA 0.46 6.64 0.51 8.85e-10 Cognitive performance; TGCT cis rs4665809 1.000 rs4665809 chr2:26251361 C/T cg25036284 chr2:26402008 FAM59B 0.54 4.7 0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg02953382 chr22:24373134 LOC391322 -0.78 -8.09 -0.59 4.76e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12935418 0.616 rs7184568 chr16:80964848 G/C cg07676361 chr16:80966860 NA -0.36 -4.73 -0.39 6.04e-6 Mean corpuscular volume; TGCT cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -8.51 -0.61 4.86e-14 Platelet count; TGCT cis rs4478037 0.558 rs72854778 chr3:33071945 G/T cg19404215 chr3:33155277 CRTAP 1.05 5.04 0.41 1.58e-6 Major depressive disorder; TGCT cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg08439880 chr3:133502540 NA -0.34 -6.61 -0.51 1e-9 Iron status biomarkers; TGCT cis rs346785 0.610 rs347674 chr17:74278548 C/G cg09812376 chr17:74270190 QRICH2 -0.48 -7.35 -0.55 2.35e-11 White matter hyperintensities in ischemic stroke; TGCT cis rs4689388 0.890 rs13130845 chr4:6297646 A/C cg25554036 chr4:6271136 WFS1 0.54 7.32 0.55 2.66e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1401999 0.606 rs7644687 chr3:183753353 A/G cg20387954 chr3:183756860 HTR3D 0.22 4.67 0.39 7.69e-6 Anterior chamber depth; TGCT cis rs6087771 0.651 rs6060775 chr20:30286191 A/G cg13852791 chr20:30311386 BCL2L1 0.54 4.74 0.39 5.76e-6 Subcortical brain region volumes;Putamen volume; TGCT cis rs11105298 0.891 rs10506972 chr12:89861529 T/C cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6089829 0.962 rs3746749 chr20:61667333 T/C cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs10411936 0.962 rs2607278 chr19:16568197 C/T cg14704714 chr19:15740395 CYP4F8 -0.27 -4.7 -0.39 6.86e-6 White blood cell count;Multiple sclerosis; TGCT cis rs12479064 0.724 rs62153852 chr2:99934713 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.75 -6.37 -0.5 3.43e-9 Chronic sinus infection; TGCT cis rs708686 0.553 rs778805 chr19:5832209 G/A cg25387410 chr19:5844109 FUT3 -0.19 -4.44 -0.37 1.99e-5 Vitamin B12 levels; TGCT cis rs6570726 0.791 rs9373466 chr6:145912016 T/C cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg02487422 chr3:49467188 NICN1 0.55 5.32 0.43 4.77e-7 Menarche (age at onset); TGCT cis rs9611565 0.592 rs28750375 chr22:41990644 A/C cg13695892 chr22:41940480 POLR3H -0.83 -7.82 -0.57 1.94e-12 Vitiligo; TGCT trans rs57221529 0.766 rs72703026 chr5:572383 G/A cg11887960 chr12:57824829 NA 1.13 9.15 0.63 1.44e-15 Lung disease severity in cystic fibrosis; TGCT cis rs6089584 0.586 rs1079755 chr20:60615262 G/A cg13770153 chr20:60521292 NA -0.41 -5.09 -0.42 1.28e-6 Body mass index; TGCT cis rs611744 0.967 rs702801 chr8:109211802 T/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs2153535 0.580 rs9393033 chr6:8521446 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs3020333 1.000 rs3020333 chr6:152010254 A/G cg22157087 chr6:152012887 ESR1 0.19 4.64 0.38 8.67e-6 Total body bone mineral density; TGCT cis rs858239 0.632 rs13438452 chr7:23174182 A/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.28 -0.43 5.64e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1729951 0.546 rs835632 chr3:136676525 A/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs9926296 0.529 rs7195906 chr16:89806347 A/T cg03388025 chr16:89894329 SPIRE2 0.49 8.27 0.6 1.71e-13 Vitiligo; TGCT cis rs7590720 1.000 rs4674048 chr2:216900023 G/A cg12620499 chr2:216877984 MREG 0.89 9.07 0.63 2.27e-15 Alcohol dependence; TGCT cis rs3770752 0.654 rs3770754 chr2:37575381 C/G cg20091297 chr2:37572423 QPCT -0.36 -4.46 -0.37 1.82e-5 Schizophrenia; TGCT cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg05025164 chr4:1340916 KIAA1530 0.78 6.44 0.5 2.36e-9 Longevity; TGCT cis rs7731657 0.509 rs2250348 chr5:130243531 T/A cg08523029 chr5:130500466 HINT1 -0.58 -4.84 -0.4 3.8e-6 Fasting plasma glucose; TGCT cis rs597539 0.652 rs478647 chr11:68700424 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 7.43 0.55 1.56e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1538970 0.962 rs9429077 chr1:45820667 C/A cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs6430585 0.528 rs614193 chr2:136653925 A/T cg07169764 chr2:136633963 MCM6 1.17 10.98 0.7 5.18e-20 Corneal structure; TGCT cis rs12142240 0.698 rs72677592 chr1:46818288 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7267979 0.789 rs62213729 chr20:25363426 C/T cg16686733 chr20:25566563 NINL -0.49 -4.62 -0.38 9.44e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6961102 0.548 rs2402968 chr7:129321647 T/C cg02041484 chr7:129266958 NRF1 -0.28 -5.1 -0.42 1.26e-6 Platelet distribution width; TGCT cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg18876405 chr7:65276391 NA 0.35 5.66 0.45 1.01e-7 Calcium levels; TGCT cis rs425277 1.000 rs262676 chr1:2078482 T/A cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs4253772 0.515 rs7287164 chr22:46781008 T/C cg26008785 chr22:46428396 NA 0.43 4.44 0.37 1.99e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs3885907 0.542 rs4147064 chr13:31320118 A/G cg22282089 chr13:30686841 NA -0.22 -4.55 -0.38 1.25e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT cis rs9400467 0.506 rs12196873 chr6:111598058 G/T cg15721981 chr6:111408429 SLC16A10 -0.68 -4.45 -0.37 1.92e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs4851254 0.920 rs11686599 chr2:100753475 A/G cg23118464 chr2:100721844 AFF3 0.74 5.52 0.44 1.86e-7 Intelligence (multi-trait analysis); TGCT trans rs17685 0.816 rs11763076 chr7:75765963 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs9300255 0.699 rs11057204 chr12:123725827 T/C cg00376283 chr12:123451042 ABCB9 0.72 5.52 0.44 1.88e-7 Neutrophil percentage of white cells; TGCT cis rs1218582 0.772 rs6686873 chr1:154913404 C/G cg09359103 chr1:154839909 KCNN3 -0.62 -11.25 -0.71 1.15e-20 Prostate cancer; TGCT cis rs514406 0.536 rs878957 chr1:53197559 C/T cg24675658 chr1:53192096 ZYG11B 0.94 13.04 0.76 5.2e-25 Monocyte count; TGCT cis rs908922 0.584 rs71626721 chr1:152532745 A/G cg20991723 chr1:152506922 NA 0.44 5.89 0.47 3.34e-8 Hair morphology; TGCT cis rs7772486 0.790 rs1062067 chr6:146207563 A/G cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.774 rs1007170 chr1:154881461 G/A cg06221963 chr1:154839813 KCNN3 -0.79 -15.15 -0.81 5.4e-30 Prostate cancer; TGCT cis rs6460942 0.687 rs74753576 chr7:12463926 G/A cg06484146 chr7:12443880 VWDE -0.53 -5.59 -0.45 1.36e-7 Coronary artery disease; TGCT cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg17054783 chr10:134559939 INPP5A 0.26 5.0 0.41 1.94e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs11088226 0.598 rs79634586 chr21:33959363 A/G cg09050820 chr6:167586206 TCP10L2 0.76 7.31 0.55 2.88e-11 Gastritis; TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg19723775 chr5:179050963 HNRNPH1 -0.52 -5.2 -0.42 8.05e-7 Lung cancer; TGCT cis rs7267979 1.000 rs1046073 chr20:25281333 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg23205692 chr1:25664452 TMEM50A 0.47 4.97 0.41 2.22e-6 Erythrocyte sedimentation rate; TGCT cis rs6988636 1.000 rs17323510 chr8:124186089 A/G cg27053337 chr8:124217698 FAM83A -0.58 -4.82 -0.4 4.13e-6 Urinary uromodulin levels; TGCT cis rs873917 0.577 rs784611 chr1:40125988 T/A cg18438793 chr1:40149837 HPCAL4 0.53 4.72 0.39 6.17e-6 Amyotrophic lateral sclerosis; TGCT cis rs2290416 0.688 rs62522171 chr8:144690832 C/A cg17524265 chr8:144659883 NAPRT1 0.71 5.5 0.44 2.05e-7 Attention deficit hyperactivity disorder; TGCT cis rs12541335 0.639 rs3923433 chr8:22169798 A/T cg07298985 chr8:22133076 PIWIL2 0.33 5.32 0.43 4.73e-7 Hypertriglyceridemia; TGCT cis rs13256369 1.000 rs9329166 chr8:8576655 C/T cg06671706 chr8:8559999 CLDN23 0.34 4.83 0.4 3.92e-6 Obesity-related traits; TGCT cis rs477895 0.713 rs12787852 chr11:63954648 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 6.47 0.5 2.06e-9 Mean platelet volume; TGCT cis rs367943 1.000 rs348948 chr5:112822452 A/C cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT trans rs1496653 0.602 rs34134134 chr3:23441604 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1691799 0.899 rs1168310 chr12:66726355 A/G cg16791601 chr12:66731901 HELB 0.28 5.96 0.47 2.39e-8 White blood cell count (basophil); TGCT cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg08280861 chr8:58055591 NA 0.53 5.96 0.47 2.44e-8 Developmental language disorder (linguistic errors); TGCT cis rs1577917 0.876 rs1582127 chr6:86697204 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.19 -0.42 8.51e-7 Response to antipsychotic treatment; TGCT cis rs5769765 0.740 rs2103932 chr22:50272515 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs7027203 0.576 rs7848045 chr9:96551824 G/A cg13679303 chr9:96623674 NA 0.53 7.66 0.57 4.68e-12 DNA methylation (variation); TGCT cis rs7523273 0.526 rs12132176 chr1:207884287 A/T cg22525895 chr1:207977042 MIR29B2 0.35 5.73 0.46 7.22e-8 Schizophrenia; TGCT cis rs6430585 0.528 rs309159 chr2:136684940 C/T cg07169764 chr2:136633963 MCM6 1.18 11.35 0.71 6.37e-21 Corneal structure; TGCT cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg04546413 chr19:29218101 NA 0.86 7.0 0.53 1.45e-10 Methadone dose in opioid dependence; TGCT cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg03303774 chr4:1407052 NA 0.28 4.64 0.38 8.56e-6 Obesity-related traits; TGCT cis rs796364 0.806 rs11688168 chr2:200916004 G/A cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT trans rs797680 0.789 rs531514 chr1:93700212 C/T cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1048238 0.506 rs848212 chr1:16263452 A/G cg22431228 chr1:16359049 CLCNKA 0.23 4.49 0.37 1.61e-5 Systolic blood pressure; TGCT cis rs10051787 0.754 rs890928 chr5:122696367 A/C cg15125798 chr5:122621645 NA -0.55 -5.01 -0.41 1.84e-6 Waist circumference; TGCT cis rs9457247 1.000 rs389956 chr6:167407254 T/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs2354432 0.607 rs1530336 chr1:146685121 G/A cg25205988 chr1:146714368 CHD1L 1.33 6.31 0.49 4.44e-9 Mitochondrial DNA levels; TGCT cis rs56339712 0.802 rs11265838 chr9:92029453 T/G ch.9.1233470F chr9:91626629 NA 0.25 4.74 0.39 5.82e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs11190604 1.000 rs7099965 chr10:102301165 A/G cg23241863 chr10:102295624 HIF1AN 0.69 5.1 0.42 1.26e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12134133 0.962 rs11120512 chr1:207413715 C/G cg02152968 chr1:207494213 CD55 -0.6 -4.67 -0.39 7.74e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs2836974 0.644 rs4818017 chr21:40690561 G/T cg11644478 chr21:40555479 PSMG1 -0.55 -4.77 -0.39 5.12e-6 Cognitive function; TGCT cis rs12530134 0.519 rs3920484 chr6:170746081 A/G cg18217622 chr6:170732253 NA 0.72 4.58 0.38 1.1e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2019137 0.868 rs6755639 chr2:113981810 A/G cg27425262 chr2:113953981 PSD4;LOC440839 0.46 6.66 0.51 7.82e-10 Lymphocyte counts; TGCT cis rs769267 0.965 rs2916068 chr19:19516433 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.25 0.43 6.3e-7 Tonsillectomy; TGCT cis rs2239547 0.563 rs4302374 chr3:52905802 T/C cg11645453 chr3:52864694 ITIH4 0.34 5.72 0.46 7.68e-8 Schizophrenia; TGCT cis rs6752107 0.967 rs11694081 chr2:234148586 A/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.91 0.4 2.8e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11648796 0.765 rs61112891 chr16:783156 G/C cg27144592 chr16:783916 NARFL 0.46 6.19 0.49 8.14e-9 Height; TGCT cis rs7208859 0.573 rs28779471 chr17:29084369 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6693567 0.565 rs1260408 chr1:150307270 T/G cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs1023500 0.596 rs133350 chr22:42429049 A/G cg15557168 chr22:42548783 NA -0.19 -4.91 -0.4 2.78e-6 Schizophrenia; TGCT cis rs17030434 0.728 rs16998891 chr4:154646419 T/G cg14289246 chr4:154710475 SFRP2 -0.81 -6.12 -0.48 1.14e-8 Electrocardiographic conduction measures; TGCT cis rs1153858 1.000 rs61365925 chr15:45650311 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs4919669 0.843 rs11191379 chr10:104482330 C/T cg05855489 chr10:104503620 C10orf26 0.71 4.5 0.37 1.57e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs9393777 0.513 rs13195210 chr6:26646521 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.872 rs57068908 chr7:1060084 A/C cg18402987 chr7:1209562 NA 0.64 5.2 0.42 8.07e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs911555 0.570 rs11625397 chr14:104027557 A/G cg26031613 chr14:104095156 KLC1 -0.57 -5.42 -0.44 3e-7 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs11719685 chr3:52676065 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.84 0.46 4.38e-8 Bipolar disorder; TGCT cis rs68170813 0.559 rs7803290 chr7:106907353 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.26 0.43 6.08e-7 Menopause (age at onset); TGCT cis rs644799 0.932 rs480079 chr11:95643777 A/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.69 -7.64 -0.57 5.09e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs644799 0.965 rs607039 chr11:95547086 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7666738 0.791 rs2903151 chr4:99027218 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.8 -7.22 -0.54 4.49e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2239547 0.522 rs2564947 chr3:53046216 C/T cg11645453 chr3:52864694 ITIH4 -0.34 -5.7 -0.46 8.3e-8 Schizophrenia; TGCT cis rs9527 0.641 rs4919684 chr10:104587024 A/G cg15744005 chr10:104629667 AS3MT -0.48 -5.82 -0.46 4.72e-8 Arsenic metabolism; TGCT cis rs6582630 0.538 rs12304844 chr12:38335870 C/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs1552244 0.882 rs3755783 chr3:10029289 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 5.74 0.46 6.73e-8 Alzheimer's disease; TGCT cis rs9368481 0.761 rs7775041 chr6:27009512 T/A cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.51 -5.56 -0.45 1.61e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11785400 0.731 rs4294163 chr8:143730830 G/T cg10596483 chr8:143751796 JRK 0.53 5.21 0.42 7.5e-7 Schizophrenia; TGCT cis rs919433 0.679 rs6741314 chr2:198526088 G/A cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs3858526 1.000 rs11039787 chr11:5965611 C/T cg13902645 chr11:5959945 NA -0.42 -4.6 -0.38 1.02e-5 DNA methylation (variation); TGCT cis rs826838 1.000 rs11183941 chr12:38851692 G/C cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs4455778 0.659 rs2058267 chr7:49015951 C/T cg26309511 chr7:48887640 NA 0.43 5.07 0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs597539 0.652 rs673821 chr11:68678718 G/T cg21862992 chr11:68658383 NA 0.44 6.12 0.48 1.14e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17376456 0.877 rs66696214 chr5:93424533 G/A cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs2692947 0.589 rs810057 chr2:97015073 T/C cg22654517 chr2:96458247 NA 0.22 5.01 0.41 1.87e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg13409248 chr3:40428643 ENTPD3 0.54 4.52 0.38 1.41e-5 Renal cell carcinoma; TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs2066819 1.000 rs2066808 chr12:56737973 A/G cg26714650 chr12:56694279 CS -1.55 -8.12 -0.59 4e-13 Psoriasis vulgaris; TGCT cis rs3733585 0.673 rs9994937 chr4:9964799 G/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.6 -0.51 1.07e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8177253 1.000 rs3811647 chr3:133484029 G/A cg08439880 chr3:133502540 NA -0.31 -5.88 -0.47 3.57e-8 Iron status biomarkers; TGCT cis rs3617 0.573 rs9850563 chr3:52912214 G/A cg10802521 chr3:52805072 NEK4 0.57 6.45 0.5 2.29e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1218582 0.772 rs1109815 chr1:154909268 A/G cg03351412 chr1:154909251 PMVK 0.52 4.89 0.4 3.05e-6 Prostate cancer; TGCT cis rs2562456 0.793 rs2562474 chr19:21646282 A/C cg01304269 chr19:21688519 ZNF429 -0.57 -4.76 -0.39 5.22e-6 Pain; TGCT cis rs6089829 0.962 rs2314130 chr20:61665129 G/T cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs9397585 0.626 rs13215045 chr6:153447516 C/T cg24028809 chr6:153414101 RGS17 0.22 4.66 0.39 8.15e-6 Body mass index; TGCT cis rs4073582 0.595 rs708472 chr11:65930990 A/G cg16950941 chr11:66035639 RAB1B 0.55 5.42 0.44 2.94e-7 Gout; TGCT cis rs1799949 0.930 rs34210004 chr17:41370337 A/T cg05368731 chr17:41323189 NBR1 1.0 11.08 0.71 2.91e-20 Menopause (age at onset); TGCT cis rs79149102 0.579 rs7167415 chr15:75302570 C/T cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs1784581 0.721 rs9365356 chr6:162414789 A/G cg17173639 chr6:162384350 PARK2 0.42 7.3 0.55 3.02e-11 Itch intensity from mosquito bite; TGCT cis rs2282802 0.685 rs7717563 chr5:139689968 A/G cg01081189 chr5:139537190 NA -0.27 -5.04 -0.41 1.6e-6 Intelligence (multi-trait analysis); TGCT cis rs12899618 0.915 rs7170506 chr15:71676235 C/T cg15179472 chr15:70736858 NA 0.31 5.22 0.42 7.29e-7 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7615952 0.932 rs3811679 chr3:125648283 A/G cg05084668 chr3:125655381 ALG1L -0.76 -6.08 -0.48 1.39e-8 Blood pressure (smoking interaction); TGCT cis rs9341808 0.690 rs9448909 chr6:80909031 G/A cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs10782582 0.593 rs11801414 chr1:76124517 G/A cg03433033 chr1:76189801 ACADM -0.63 -7.27 -0.55 3.6e-11 Daytime sleep phenotypes; TGCT cis rs2721195 0.614 rs12719778 chr8:145879883 T/C cg17328964 chr8:145687451 CYHR1 -0.44 -5.83 -0.46 4.54e-8 Age at first birth; TGCT cis rs9443645 0.901 rs9361451 chr6:79555055 T/C cg09184832 chr6:79620586 NA -0.48 -5.35 -0.43 4.01e-7 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.783 rs4793992 chr17:47008207 A/G cg00947319 chr17:47005597 UBE2Z -0.2 -4.74 -0.39 5.83e-6 Type 2 diabetes; TGCT cis rs447735 0.565 rs10852626 chr16:89914633 T/G cg26513180 chr16:89883248 FANCA 0.7 6.45 0.5 2.27e-9 Hemoglobin concentration; TGCT cis rs12497850 0.931 rs7623023 chr3:48914238 G/A cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs2439831 1.000 rs2251538 chr15:43767209 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs853679 0.517 rs9357065 chr6:28129580 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs1891275 0.515 rs7475294 chr10:93508199 T/C cg07889827 chr10:93443413 NA -0.32 -6.8 -0.52 3.95e-10 Intelligence (multi-trait analysis); TGCT cis rs2073300 1.000 rs6114137 chr20:23457264 G/A cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs10838634 0.803 rs61898529 chr11:46905731 G/A cg18332754 chr11:46939436 LRP4 0.87 4.48 0.37 1.68e-5 Schizophrenia; TGCT cis rs7611238 0.583 rs59004692 chr3:195151174 G/A cg27323046 chr3:195102265 ACAP2 0.37 4.97 0.41 2.17e-6 Body mass index; TGCT cis rs2836974 0.545 rs8128901 chr21:40710419 G/A cg11644478 chr21:40555479 PSMG1 0.65 6.26 0.49 5.75e-9 Cognitive function; TGCT cis rs9814567 0.929 rs1534027 chr3:134284662 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.18 -0.64 1.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9611565 0.506 rs4822020 chr22:41700203 C/T cg03806693 chr22:41940476 POLR3H -0.82 -7.85 -0.58 1.7e-12 Vitiligo; TGCT cis rs7647973 1.000 rs3448 chr3:49396751 T/C cg05785598 chr3:49045655 WDR6 0.39 4.66 0.39 7.89e-6 Menarche (age at onset); TGCT cis rs12477438 0.520 rs13035311 chr2:99717322 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs9302001 0.920 rs9516478 chr13:95459696 T/C cg07483244 chr13:95358924 NA 0.37 4.81 0.4 4.22e-6 Panic disorder; TGCT cis rs2354432 0.556 rs2275249 chr1:146759320 C/G cg25205988 chr1:146714368 CHD1L 1.19 6.06 0.48 1.51e-8 Mitochondrial DNA levels; TGCT cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg21724239 chr8:58056113 NA 0.41 4.87 0.4 3.33e-6 Developmental language disorder (linguistic errors); TGCT cis rs4654899 0.897 rs10799668 chr1:21169385 T/C cg01072550 chr1:21505969 NA 0.48 7.58 0.56 7.09e-12 Superior frontal gyrus grey matter volume; TGCT cis rs9611565 0.649 rs9623450 chr22:42175231 G/A cg13695892 chr22:41940480 POLR3H 0.8 7.65 0.57 4.87e-12 Vitiligo; TGCT cis rs11969893 0.737 rs1358758 chr6:101411891 T/C cg12253828 chr6:101329408 ASCC3 1.08 5.14 0.42 1.06e-6 Economic and political preferences (immigration/crime); TGCT cis rs35160687 0.865 rs10189492 chr2:86478902 G/A cg03171300 chr2:86307199 POLR1A 0.32 5.53 0.44 1.83e-7 Night sleep phenotypes; TGCT cis rs7772486 0.754 rs1055212 chr6:146058315 A/T cg13319975 chr6:146136371 FBXO30 0.56 5.0 0.41 1.9e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9787249 0.957 rs56064244 chr1:40213890 C/T cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs10501293 1.000 rs4755695 chr11:43108344 C/A cg03447554 chr11:43094025 NA -0.5 -6.92 -0.53 2.09e-10 Cognitive performance; TGCT trans rs916888 0.610 rs199444 chr17:44818276 T/C cg22968622 chr17:43663579 NA 1.06 10.16 0.67 5.09e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9348721 0.673 rs9358934 chr6:26363755 G/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Intelligence (multi-trait analysis); TGCT cis rs12188164 0.714 rs11741954 chr5:421455 G/T cg22025206 chr5:502436 SLC9A3 -0.25 -4.44 -0.37 1.94e-5 Cystic fibrosis severity; TGCT cis rs28595532 0.920 rs114094671 chr4:119753540 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7666738 0.962 rs2865985 chr4:99068009 T/C cg18180107 chr4:99064573 C4orf37 0.56 4.54 0.38 1.33e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs4730250 0.634 rs11767623 chr7:106792332 C/T cg02696742 chr7:106810147 HBP1 0.72 5.89 0.47 3.44e-8 Osteoarthritis; TGCT cis rs826838 0.935 rs11183940 chr12:38851642 A/G cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs7666738 0.830 rs1025203 chr4:99023073 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.56 0.45 1.59e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7819412 0.643 rs7829396 chr8:10999583 C/T cg03192020 chr8:11204681 TDH -0.52 -4.5 -0.37 1.53e-5 Triglycerides; TGCT cis rs9660180 0.967 rs12040325 chr1:1702436 G/A cg03396347 chr1:1875803 NA -0.36 -6.58 -0.51 1.17e-9 Body mass index; TGCT cis rs137603 0.644 rs137619 chr22:39706360 A/C cg17798944 chr22:39715225 SNORD43;RPL3 -0.69 -7.04 -0.53 1.16e-10 Primary biliary cholangitis; TGCT cis rs8017423 0.630 rs12589687 chr14:90819570 C/G cg04374321 chr14:90722782 PSMC1 -0.56 -5.59 -0.45 1.38e-7 Mortality in heart failure; TGCT cis rs644799 0.526 rs506180 chr11:95623109 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.49 5.08 0.41 1.38e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg11494091 chr17:61959527 GH2 0.44 7.33 0.55 2.58e-11 Height; TGCT cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg20276088 chr3:133502917 NA -0.27 -5.59 -0.45 1.38e-7 Iron status biomarkers; TGCT cis rs7937682 0.575 rs7107213 chr11:111750430 A/G cg09085632 chr11:111637200 PPP2R1B 0.88 8.5 0.61 5.19e-14 Primary sclerosing cholangitis; TGCT cis rs5750830 0.649 rs5750813 chr22:39795228 G/C cg05872129 chr22:39784769 NA -1.01 -11.01 -0.7 4.35e-20 Intelligence (multi-trait analysis); TGCT trans rs1499614 1.000 rs1267817 chr7:66110040 G/T cg07424592 chr7:64974309 NA 1.31 7.65 0.57 4.73e-12 Gout; TGCT cis rs56309584 0.715 rs11651199 chr17:8142644 G/A cg08322244 chr17:8066669 VAMP2 -0.55 -4.98 -0.41 2.08e-6 Initial pursuit acceleration; TGCT cis rs7255045 0.752 rs10404876 chr19:12987605 T/C cg23899408 chr19:12877188 HOOK2 -0.61 -5.01 -0.41 1.79e-6 Mean corpuscular volume; TGCT cis rs6430585 0.583 rs111837148 chr2:136612036 G/A cg07169764 chr2:136633963 MCM6 1.23 11.92 0.73 2.66e-22 Corneal structure; TGCT cis rs1215050 0.765 rs644839 chr4:98716357 C/A cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 1.95e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12188164 0.965 rs77101200 chr5:443059 G/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.73 -0.39 6.02e-6 Cystic fibrosis severity; TGCT cis rs33794 0.934 rs33796 chr3:45302287 C/T cg18645101 chr3:44551900 NA 0.53 4.64 0.38 8.89e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs28595532 0.920 rs116091383 chr4:119635518 A/G cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT cis rs986417 0.818 rs7156317 chr14:61087740 G/A cg18240143 chr14:60952599 C14orf39 0.88 4.57 0.38 1.15e-5 Gut microbiota (bacterial taxa); TGCT cis rs6540559 0.546 rs74991018 chr1:210033790 T/G cg23283495 chr1:209979779 IRF6 0.67 4.99 0.41 1.96e-6 Cleft lip with or without cleft palate; TGCT cis rs453301 0.606 rs6601279 chr8:8908231 G/A cg15556689 chr8:8085844 FLJ10661 -0.68 -5.58 -0.45 1.44e-7 Joint mobility (Beighton score); TGCT cis rs1008375 0.932 rs6844593 chr4:17659039 T/C cg10189774 chr4:17578691 LAP3 0.55 4.83 0.4 3.89e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.525 rs9611548 chr22:41704143 G/T cg03806693 chr22:41940476 POLR3H -0.82 -8.35 -0.6 1.13e-13 Vitiligo; TGCT cis rs7208859 0.614 rs28758251 chr17:29223312 A/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9677476 0.516 rs6746156 chr2:231967210 A/G cg07929768 chr2:232055508 NA 0.34 5.31 0.43 4.92e-7 Food antigen IgG levels; TGCT cis rs1577917 0.958 rs13201730 chr6:86556647 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -5.02 -0.41 1.74e-6 Response to antipsychotic treatment; TGCT cis rs709400 0.663 rs62007681 chr14:103884651 G/A cg12935359 chr14:103987150 CKB -0.36 -5.47 -0.44 2.42e-7 Body mass index; TGCT cis rs4767364 0.961 rs10850031 chr12:112771063 T/G cg10833066 chr12:111807467 FAM109A 0.33 5.1 0.42 1.23e-6 Oral cavity and pharyngeal cancer; TGCT cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg13395646 chr4:1353034 KIAA1530 -0.39 -4.96 -0.41 2.3e-6 Obesity-related traits; TGCT cis rs208520 1.000 rs9453663 chr6:66976077 A/G cg07460842 chr6:66804631 NA 0.77 6.83 0.52 3.34e-10 Exhaled nitric oxide output; TGCT cis rs651907 0.557 rs17347644 chr3:101547733 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.37 0.68 1.61e-18 Colorectal cancer; TGCT cis rs4689592 0.503 rs59640165 chr4:7051661 G/A cg25660036 chr4:7070649 GRPEL1 0.59 4.49 0.37 1.62e-5 Monocyte percentage of white cells; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg10150615 chr22:24372951 LOC391322 -0.77 -6.8 -0.52 3.96e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1062177 0.826 rs1549920 chr5:151140844 A/T cg12924095 chr5:151150029 G3BP1 0.35 5.02 0.41 1.75e-6 Preschool internalizing problems; TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.78 -0.39 4.77e-6 Prudent dietary pattern; TGCT cis rs1403694 1.000 rs1648716 chr3:186439529 C/T cg12454167 chr3:186435060 KNG1 0.42 7.32 0.55 2.77e-11 Blood protein levels; TGCT cis rs3020736 0.500 rs4147640 chr22:42485292 T/C cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2816062 0.813 rs2745325 chr1:18880442 C/A cg18795169 chr1:18902165 NA -0.59 -13.16 -0.76 2.73e-25 Urate levels in lean individuals; TGCT cis rs7914558 1.000 rs2275271 chr10:104814162 T/C cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.67e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs782590 0.748 rs782634 chr2:55897700 T/C cg03859395 chr2:55845619 SMEK2 0.76 7.72 0.57 3.36e-12 Metabolic syndrome; TGCT cis rs11031096 0.536 rs894459 chr11:4213590 A/G cg18678763 chr11:4115507 RRM1 -0.39 -5.0 -0.41 1.92e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg23221052 chr5:179740743 GFPT2 -0.35 -5.54 -0.45 1.74e-7 Height; TGCT cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg16145915 chr7:1198662 ZFAND2A -0.51 -6.55 -0.51 1.37e-9 Longevity;Endometriosis; TGCT cis rs1453308 0.766 rs1470861 chr2:237176942 A/G cg19324714 chr2:237145437 ASB18 0.59 5.22 0.42 7.18e-7 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs910187 0.678 rs3818006 chr20:45816328 A/G cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs8016982 0.633 rs8019108 chr14:81716781 A/T cg01989461 chr14:81687754 GTF2A1 0.76 7.5 0.56 1.09e-11 Schizophrenia; TGCT cis rs12220898 0.679 rs12254955 chr10:50480763 T/G cg09603381 chr10:49954066 WDFY4 0.39 4.48 0.37 1.68e-5 Inflammatory biomarkers; TGCT cis rs9325144 0.723 rs1586373 chr12:39181582 G/A cg26384229 chr12:38710491 ALG10B -0.61 -5.67 -0.45 9.5e-8 Morning vs. evening chronotype; TGCT cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.45 -4.89 -0.4 3.04e-6 Blood metabolite levels; TGCT cis rs4285028 0.747 rs7610298 chr3:121419100 T/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg10047753 chr17:41438598 NA 0.96 9.86 0.66 2.71e-17 Menopause (age at onset); TGCT cis rs28595532 0.920 rs116548907 chr4:119735285 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.4 0.5 2.94e-9 Cannabis dependence symptom count; TGCT cis rs6570726 0.935 rs12663204 chr6:145818373 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9853921 0.674 rs9843209 chr3:117966601 C/T cg15509235 chr3:117715573 NA -0.53 -4.51 -0.38 1.46e-5 JT interval (sulfonylurea treatment interaction); TGCT cis rs4269383 0.692 rs4513805 chr6:156224697 G/A cg15940508 chr6:156885744 NA -0.29 -4.47 -0.37 1.73e-5 Pancreatic cancer; TGCT cis rs7267979 0.816 rs6076358 chr20:25519403 G/T cg03522245 chr20:25566470 NINL -0.56 -5.79 -0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Vitiligo; TGCT cis rs79349575 0.783 rs4793995 chr17:47019399 A/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs78487399 0.808 rs6746610 chr2:43677253 T/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs28595532 0.920 rs114724233 chr4:119754918 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2243480 1.000 rs4149468 chr7:65825690 T/C cg20637647 chr7:64974828 NA 0.92 5.09 0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs7523273 0.606 rs2761433 chr1:207917361 G/A cg22525895 chr1:207977042 MIR29B2 0.54 8.77 0.62 1.16e-14 Schizophrenia; TGCT cis rs1865760 0.532 rs1061482 chr6:26086699 G/T cg17042849 chr6:26104293 HIST1H4C -0.63 -5.46 -0.44 2.52e-7 Height; TGCT cis rs4253772 0.550 rs738444 chr22:46721088 C/T cg26492175 chr22:47022658 GRAMD4 0.19 4.5 0.37 1.54e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs1371867 0.875 rs7830342 chr8:101327738 T/A cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs1799949 1.000 rs915945 chr17:41179864 C/T cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs10779751 0.686 rs2791656 chr1:11128329 A/G cg08854313 chr1:11322531 MTOR 0.85 6.96 0.53 1.74e-10 Body mass index; TGCT cis rs1215050 0.740 rs783924 chr4:98969234 C/T cg05340658 chr4:99064831 C4orf37 -0.43 -5.27 -0.43 5.8e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg03388025 chr16:89894329 SPIRE2 -0.32 -4.76 -0.39 5.26e-6 Vitiligo; TGCT cis rs6964587 0.934 rs6973792 chr7:91749798 C/A cg22709100 chr7:91322751 NA 0.29 4.66 0.39 8e-6 Breast cancer; TGCT cis rs11098499 0.775 rs2002049 chr4:120257417 A/G cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Corneal astigmatism; TGCT cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT cis rs5750830 0.620 rs1007337 chr22:39781585 C/T cg24399712 chr22:39784796 NA -1.03 -11.98 -0.73 1.92e-22 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.22 0.42 7.44e-7 Platelet count; TGCT cis rs1215050 0.904 rs890469 chr4:98923293 T/C cg17366294 chr4:99064904 C4orf37 -0.49 -4.91 -0.4 2.87e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13256369 0.774 rs13248423 chr8:8577602 C/G cg18904891 chr8:8559673 CLDN23 0.56 4.95 0.41 2.38e-6 Obesity-related traits; TGCT cis rs2233152 0.520 rs56101381 chr19:41272902 T/C cg23743927 chr19:41304969 EGLN2 -0.7 -4.69 -0.39 7.06e-6 Kawasaki disease; TGCT cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg05890377 chr2:74357713 NA 0.5 6.63 0.51 9.26e-10 Gestational age at birth (maternal effect); TGCT cis rs35306767 0.714 rs28512382 chr10:1092195 G/C cg26597838 chr10:835615 NA 0.61 7.02 0.53 1.3100000000000001e-10 Eosinophil percentage of granulocytes; TGCT cis rs9341808 0.935 rs2322633 chr6:80845989 C/T cg08355045 chr6:80787529 NA -0.34 -5.67 -0.45 9.48e-8 Sitting height ratio; TGCT cis rs2188554 0.740 rs213948 chr7:117194470 G/A cg09181792 chr7:117119393 CFTR 0.48 4.44 0.37 1.99e-5 Esophageal adenocarcinoma; TGCT cis rs4808199 0.895 rs10419672 chr19:19471241 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.66 4.91 0.4 2.86e-6 Nonalcoholic fatty liver disease; TGCT cis rs7635838 0.654 rs347585 chr3:11286220 C/T cg00170343 chr3:11313890 ATG7 0.69 6.8 0.52 4.01e-10 HDL cholesterol; TGCT cis rs7666738 0.830 rs58367603 chr4:99015350 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg22920501 chr2:26401640 FAM59B -0.78 -6.16 -0.48 9.43e-9 Gut microbiome composition (summer); TGCT cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.62 -5.07 -0.41 1.42e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12681287 0.547 rs60982560 chr8:87515046 C/T cg19078186 chr8:87526527 CPNE3 -0.36 -4.49 -0.37 1.59e-5 Caudate activity during reward; TGCT cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg08645402 chr16:4508243 NA 0.21 5.05 0.41 1.57e-6 Schizophrenia; TGCT cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs9291683 0.530 rs73227883 chr4:9979279 T/C cg00071950 chr4:10020882 SLC2A9 0.65 8.35 0.6 1.17e-13 Bone mineral density; TGCT cis rs6866344 0.697 rs61247551 chr5:178133503 G/A cg10224037 chr5:178157518 ZNF354A 0.95 8.47 0.61 6.06e-14 Neutrophil percentage of white cells; TGCT cis rs13191362 1.000 rs36113695 chr6:163004733 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs8016982 0.633 rs9944085 chr14:81717620 A/T cg01989461 chr14:81687754 GTF2A1 -0.76 -7.5 -0.56 1.09e-11 Schizophrenia; TGCT cis rs7542091 0.813 rs2049999 chr1:210031331 A/G cg22029157 chr1:209979665 IRF6 0.55 5.35 0.43 4e-7 Monobrow; TGCT cis rs739496 0.793 rs1557685 chr12:111901204 C/A cg10833066 chr12:111807467 FAM109A 0.37 5.65 0.45 1.05e-7 Platelet count; TGCT cis rs1784581 0.674 rs1789989 chr6:162408138 C/T cg17173639 chr6:162384350 PARK2 0.42 7.17 0.54 6e-11 Itch intensity from mosquito bite; TGCT cis rs2072499 0.695 rs112223391 chr1:156156094 G/A cg25208724 chr1:156163844 SLC25A44 1.0 9.0 0.63 3.2e-15 Testicular germ cell tumor; TGCT cis rs4409675 0.576 rs2749110 chr1:28235010 T/C cg23691781 chr1:28212827 C1orf38 0.26 5.52 0.44 1.9e-7 Corneal astigmatism; TGCT cis rs4273100 0.688 rs28582509 chr17:19165179 T/C cg03910582 chr17:19030146 GRAPL 0.51 6.18 0.49 8.57e-9 Schizophrenia; TGCT cis rs13191362 1.000 rs67840803 chr6:163049048 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.5 0.61 5.17e-14 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1008375 1.000 rs13148861 chr4:17688338 G/A cg18681998 chr4:17616180 MED28 -0.91 -8.93 -0.63 4.82e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs501916 0.743 rs3743281 chr15:48056958 C/T cg16110827 chr15:48056943 SEMA6D -0.16 -4.49 -0.37 1.63e-5 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs9926296 0.528 rs4785721 chr16:89839997 G/A cg27121462 chr16:89883253 FANCA 0.76 7.93 0.58 1.07e-12 Vitiligo; TGCT cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg05025164 chr4:1340916 KIAA1530 0.79 6.65 0.51 8.3e-10 Longevity; TGCT cis rs4699052 0.963 rs7679365 chr4:104212980 G/C cg16532752 chr4:104119610 CENPE -0.56 -5.1 -0.42 1.26e-6 Testicular germ cell tumor; TGCT trans rs57221529 0.713 rs12522724 chr5:590742 T/C cg25482853 chr8:67687455 SGK3 1.22 10.56 0.69 5.48e-19 Lung disease severity in cystic fibrosis; TGCT cis rs11030122 0.702 rs67300156 chr11:3953949 C/T cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs12712073 0.845 rs6729966 chr2:100781566 A/G cg22139774 chr2:100720529 AFF3 -0.35 -5.55 -0.45 1.63e-7 Intelligence (multi-trait analysis); TGCT cis rs1005224 0.963 rs2303345 chr14:76156609 A/G cg04684003 chr14:76127793 TTLL5;C14orf1 0.61 5.57 0.45 1.51e-7 Large artery stroke; TGCT cis rs9911578 1.000 rs11079365 chr17:56945430 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.521 rs6939827 chr6:8461360 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10986311 0.962 rs10818943 chr9:127087740 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.44 -0.37 1.97e-5 Vitiligo; TGCT cis rs11098499 1.000 rs11098499 chr4:120187611 C/T cg09307838 chr4:120376055 NA 0.49 4.48 0.37 1.67e-5 Corneal astigmatism; TGCT cis rs7917772 0.503 rs746552 chr10:104342501 A/G cg05855489 chr10:104503620 C10orf26 -0.61 -5.41 -0.44 3.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs365060 0.818 rs154998 chr2:109577205 C/T cg13735819 chr19:2253850 JSRP1 0.7 6.65 0.51 8.52e-10 Beard thickness; TGCT cis rs453301 0.592 rs4841084 chr8:8883905 C/T cg06636001 chr8:8085503 FLJ10661 0.81 7.06 0.54 1.06e-10 Joint mobility (Beighton score); TGCT cis rs4654899 0.827 rs12564330 chr1:21207495 A/C cg01072550 chr1:21505969 NA 0.49 7.75 0.57 2.82e-12 Superior frontal gyrus grey matter volume; TGCT cis rs750134 0.901 rs1549087 chr12:109201326 T/C cg14311481 chr12:108920534 SART3 0.57 4.48 0.37 1.7e-5 Low high density lipoprotein cholesterol levels; TGCT cis rs6860806 0.507 rs582490 chr5:131710095 G/A cg24060327 chr5:131705240 SLC22A5 0.78 8.46 0.61 6.22e-14 Breast cancer; TGCT cis rs4783244 0.862 rs7198176 chr16:82647971 C/T cg09415485 chr16:82663111 CDH13 -0.26 -4.82 -0.4 4.05e-6 Adiponectin levels; TGCT cis rs3087591 0.659 rs757377 chr17:29720426 G/A cg24425628 chr17:29625626 OMG;NF1 0.41 6.03 0.48 1.73e-8 Hip circumference; TGCT cis rs73198271 0.813 rs56007835 chr8:8610026 G/A cg06671706 chr8:8559999 CLDN23 -0.37 -4.75 -0.39 5.45e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs4665809 0.938 rs35844686 chr2:26304949 A/G cg25036284 chr2:26402008 FAM59B 0.58 4.58 0.38 1.12e-5 Gut microbiome composition (summer); TGCT trans rs1814175 0.519 rs10839291 chr11:49514321 G/A cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Height; TGCT cis rs7394190 0.748 rs11000766 chr10:75512952 C/T cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.48e-6 Incident atrial fibrillation; TGCT cis rs910316 1.000 rs8017642 chr14:75590822 G/A cg11812906 chr14:75593930 NEK9 0.73 7.23 0.54 4.36e-11 Height; TGCT cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs3885907 0.520 rs9671182 chr13:31321138 C/G cg22282089 chr13:30686841 NA 0.22 4.54 0.38 1.33e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT cis rs3772130 0.885 rs9816844 chr3:121496324 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs76878669 0.561 rs1892940 chr11:66111251 A/G cg18002602 chr11:66138449 SLC29A2 -0.51 -6.25 -0.49 6.06e-9 Educational attainment (years of education); TGCT cis rs597539 0.654 rs655816 chr11:68626405 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 7.76 0.57 2.67e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT trans rs2727020 0.553 rs4103567 chr11:49255389 C/T cg15704280 chr7:45808275 SEPT13 -0.6 -6.71 -0.52 6.07e-10 Coronary artery disease; TGCT cis rs2836974 0.644 rs2836982 chr21:40689171 C/A cg06238570 chr21:40685208 BRWD1 -0.81 -8.52 -0.61 4.45e-14 Cognitive function; TGCT cis rs3781684 1.000 rs2233551 chr11:76814471 A/G cg17957640 chr11:76839205 MYO7A -0.48 -4.75 -0.39 5.46e-6 Cognitive performance; TGCT cis rs734999 0.967 rs10797434 chr1:2511280 C/T cg18854424 chr1:2615690 NA 0.46 5.84 0.46 4.22e-8 Ulcerative colitis; TGCT cis rs10782582 0.586 rs112368938 chr1:76336339 C/T cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs7647973 0.626 rs1352889 chr3:49652148 T/C cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs7937682 0.602 rs11214036 chr11:111773169 C/T cg09085632 chr11:111637200 PPP2R1B -0.98 -9.59 -0.65 1.21e-16 Primary sclerosing cholangitis; TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.48 0.56 1.17e-11 Prudent dietary pattern; TGCT cis rs3796352 1.000 rs71301809 chr3:53090312 C/T cg15956490 chr3:53032818 SFMBT1 0.6 6.78 0.52 4.31e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7617480 0.558 rs12715430 chr3:48942855 A/C cg07636037 chr3:49044803 WDR6 0.78 6.5 0.5 1.73e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9436747 0.641 rs7413467 chr1:66047893 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.03 0.41 1.69e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7666738 0.800 rs28427190 chr4:98989106 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg04267008 chr7:1944627 MAD1L1 -0.37 -4.85 -0.4 3.56e-6 Bipolar disorder and schizophrenia; TGCT cis rs2404602 0.583 rs2176623 chr15:76568579 C/T cg26408565 chr15:76604113 ETFA -0.44 -5.88 -0.47 3.6e-8 Blood metabolite levels; TGCT cis rs2857078 0.720 rs9901595 chr17:42305699 G/A cg19774624 chr17:42201019 HDAC5 -0.69 -7.14 -0.54 6.91e-11 Red cell distribution width;Reticulocyte count; TGCT cis rs854765 0.547 rs9912096 chr17:17896673 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.27 0.6 1.72e-13 Total body bone mineral density; TGCT cis rs79349575 0.716 rs46522 chr17:46988597 C/T cg26022315 chr17:47021804 SNF8 0.49 4.97 0.41 2.22e-6 Type 2 diabetes; TGCT cis rs7666738 0.581 rs34205844 chr4:98887494 C/A cg18180107 chr4:99064573 C4orf37 0.51 4.51 0.38 1.47e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.867 rs3213990 chr15:43670226 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs7267979 1.000 rs2297496 chr20:25295787 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2777491 1.000 rs316609 chr15:41743828 T/A cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.07 -0.71 3.15e-20 Ulcerative colitis; TGCT cis rs67311347 0.956 rs6771527 chr3:40506548 T/C cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs2439831 0.850 rs67541383 chr15:44172548 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.86 5.54 0.45 1.72e-7 Lung cancer in ever smokers; TGCT cis rs473651 0.904 rs501333 chr2:239336045 G/A cg21699342 chr2:239360505 ASB1 0.17 4.78 0.39 4.78e-6 Multiple system atrophy; TGCT cis rs13256369 1.000 rs13282915 chr8:8570891 T/G cg17143192 chr8:8559678 CLDN23 0.58 5.56 0.45 1.56e-7 Obesity-related traits; TGCT cis rs600231 0.708 rs682845 chr11:65254201 A/G cg21890820 chr11:65308645 LTBP3 0.35 4.44 0.37 1.93e-5 Bone mineral density; TGCT cis rs7213347 0.581 rs2873195 chr17:2064702 A/T cg22033759 chr17:1182267 TUSC5 -0.23 -4.65 -0.39 8.44e-6 Total body bone mineral density; TGCT cis rs6952808 0.595 rs3800917 chr7:2167939 A/G cg22963979 chr7:1858916 MAD1L1 0.41 6.66 0.51 7.94e-10 Bipolar disorder and schizophrenia; TGCT cis rs2050392 0.829 rs306589 chr10:30723831 A/G cg18806716 chr10:30721971 MAP3K8 -0.49 -5.65 -0.45 1.04e-7 Inflammatory bowel disease; TGCT cis rs8017423 0.647 rs1958346 chr14:90824011 G/T cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs3008870 0.755 rs2815366 chr1:67499930 C/T cg11518657 chr1:67396239 MIER1 0.47 4.61 0.38 9.68e-6 Lymphocyte percentage of white cells; TGCT cis rs4849845 0.678 rs3896632 chr2:121023496 C/T cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs3820928 0.933 rs1429267 chr2:227767593 G/C cg11843606 chr2:227700838 RHBDD1 -0.51 -4.49 -0.37 1.6e-5 Pulmonary function; TGCT cis rs13242816 1.000 rs3807988 chr7:116180735 A/C cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs1799949 0.965 rs7223952 chr17:41194885 T/C cg23758822 chr17:41437982 NA 0.67 6.5 0.5 1.8e-9 Menopause (age at onset); TGCT cis rs28374715 0.609 rs8043237 chr15:41514298 G/A cg18705301 chr15:41695430 NDUFAF1 -0.78 -10.91 -0.7 7.59e-20 Ulcerative colitis; TGCT cis rs67311347 1.000 rs56303661 chr3:40520778 C/G cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg12310025 chr6:25882481 NA -0.68 -6.01 -0.47 1.96e-8 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.918 rs9538 chr22:41755857 G/T cg06634786 chr22:41940651 POLR3H -0.91 -8.79 -0.62 1.02e-14 Vitiligo; TGCT trans rs7824557 0.564 rs2736300 chr8:11235579 T/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.48e-10 Retinal vascular caliber; TGCT cis rs7617773 0.707 rs13061269 chr3:48373343 C/T cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs12210905 0.688 rs12205044 chr6:27478990 A/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs56309584 0.560 rs3027160 chr17:8057572 T/C cg08322244 chr17:8066669 VAMP2 -0.52 -4.88 -0.4 3.14e-6 Initial pursuit acceleration; TGCT cis rs66573146 1.000 rs7686168 chr4:6986057 C/A cg01220768 chr4:7056774 TADA2B 0.39 4.91 0.4 2.77e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs13102973 0.720 rs7687463 chr4:135885773 G/T cg14419869 chr4:135874104 NA 0.26 4.79 0.39 4.72e-6 Subjective well-being; TGCT cis rs12478296 0.901 rs7603560 chr2:243043256 C/T cg06360820 chr2:242988706 NA -0.81 -5.39 -0.44 3.36e-7 Obesity-related traits; TGCT cis rs7681440 0.904 rs6532193 chr4:90764188 G/A cg26578617 chr4:90757533 SNCA -0.49 -5.1 -0.42 1.26e-6 Dementia with Lewy bodies; TGCT cis rs10927875 0.541 rs1763599 chr1:16342602 C/T cg21385522 chr1:16154831 NA 0.46 4.75 0.39 5.5e-6 Dilated cardiomyopathy; TGCT cis rs4906332 0.868 rs4900578 chr14:103926010 A/T cg26031613 chr14:104095156 KLC1 -0.53 -4.71 -0.39 6.62e-6 Coronary artery disease; TGCT cis rs651907 0.535 rs34063583 chr3:101509948 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs3796352 1.000 rs35163227 chr3:53127876 A/G cg07884673 chr3:53033167 SFMBT1 0.53 5.23 0.43 6.94e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2841277 0.708 rs11623422 chr14:105407031 A/G cg21017887 chr14:105400489 NA 0.37 5.19 0.42 8.23e-7 Rheumatoid arthritis; TGCT cis rs4803468 0.935 rs12602 chr19:41889748 T/C cg09537434 chr19:41945824 ATP5SL -0.89 -9.97 -0.67 1.47e-17 Height; TGCT cis rs3796619 1.000 rs4974601 chr4:1095410 G/A cg27284194 chr4:1044797 NA 0.47 4.57 0.38 1.17e-5 Recombination rate (males); TGCT cis rs7172809 0.573 rs2292594 chr15:77515140 T/C cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT cis rs912057 0.833 rs1294418 chr6:6742185 A/G cg06612196 chr6:6737390 NA 0.37 4.88 0.4 3.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9549367 0.756 rs2316463 chr13:113901406 C/T cg18105134 chr13:113819100 PROZ -0.34 -5.61 -0.45 1.28e-7 Platelet distribution width; TGCT cis rs34172651 0.517 rs7204288 chr16:24784531 A/G cg06028605 chr16:24865363 SLC5A11 0.41 4.58 0.38 1.13e-5 Intelligence (multi-trait analysis); TGCT cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg18735214 chr6:43276756 CRIP3 -0.56 -4.88 -0.4 3.24e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9467711 0.538 rs35934643 chr6:26355094 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7552404 1.000 rs4949879 chr1:76237143 G/A cg03433033 chr1:76189801 ACADM 0.82 9.39 0.64 3.73e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs597539 0.690 rs647661 chr11:68625875 T/C cg21862992 chr11:68658383 NA 0.49 6.65 0.51 8.18e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg13699009 chr12:122356056 WDR66 0.26 5.44 0.44 2.72e-7 Mean corpuscular volume; TGCT cis rs4654899 0.567 rs9426735 chr1:21505472 A/T cg01072550 chr1:21505969 NA -0.53 -8.49 -0.61 5.22e-14 Superior frontal gyrus grey matter volume; TGCT cis rs782590 0.764 rs2054728 chr2:55818419 C/T cg18811423 chr2:55921094 PNPT1 0.55 5.65 0.45 1.03e-7 Metabolic syndrome; TGCT cis rs6594499 0.500 rs12514810 chr5:110455357 T/A cg04022379 chr5:110408740 TSLP 0.56 5.89 0.47 3.43e-8 Allergic disease (asthma, hay fever or eczema); TGCT cis rs950169 0.922 rs2033284 chr15:84946273 C/T cg17173187 chr15:85201210 NMB 0.57 5.74 0.46 6.94e-8 Schizophrenia; TGCT cis rs2243480 1.000 rs73142166 chr7:65375832 A/G cg20637647 chr7:64974828 NA 0.96 5.29 0.43 5.33e-7 Diabetic kidney disease; TGCT cis rs860554 0.640 rs2268153 chr1:201262184 A/G cg01022117 chr1:201258280 PKP1 -0.35 -6.72 -0.52 5.78e-10 Panic disorder; TGCT cis rs9303401 0.614 rs8081058 chr17:57160513 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs597539 0.652 rs584108 chr11:68630282 A/T cg06112835 chr11:68658793 MRPL21 -0.45 -7.67 -0.57 4.3e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 1.000 rs73591706 chr8:58195633 C/T cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs12042938 0.579 rs980394 chr1:231779507 A/G cg04892437 chr1:231737901 TSNAX-DISC1 -0.43 -4.6 -0.38 1.01e-5 Neuranatomic and neurocognitive phenotypes; TGCT cis rs7769051 0.521 rs9321367 chr6:133084359 G/T cg22852734 chr6:133119734 C6orf192 1.26 5.6 0.45 1.33e-7 Type 2 diabetes nephropathy; TGCT cis rs2019137 0.936 rs2305133 chr2:113956821 C/G cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs7267979 0.833 rs6138556 chr20:25243310 C/T cg16686733 chr20:25566563 NINL 0.56 5.76 0.46 6.24e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1908814 0.516 rs11996277 chr8:11800031 G/A cg15556689 chr8:8085844 FLJ10661 0.79 7.38 0.55 1.96e-11 Neuroticism; TGCT cis rs6594499 0.542 rs4530809 chr5:110462230 A/G cg04022379 chr5:110408740 TSLP 0.61 5.64 0.45 1.11e-7 Allergic disease (asthma, hay fever or eczema); TGCT cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg07507251 chr3:52567010 NT5DC2 0.48 6.67 0.51 7.55e-10 Bipolar disorder; TGCT cis rs13343954 0.778 rs10425798 chr19:33541539 C/G cg07624008 chr19:33672378 NA -0.27 -4.61 -0.38 9.73e-6 Colorectal cancer; TGCT cis rs3027009 0.881 rs61828178 chr1:159159041 G/T cg17025555 chr1:158724362 OR6K6 -0.46 -4.46 -0.37 1.81e-5 Lean body mass and age at menarche (combined); TGCT cis rs2797160 1.000 rs1612249 chr6:126014916 C/A cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs2730260 0.537 rs3793223 chr7:158863574 C/A cg12144100 chr7:157890277 PTPRN2 0.35 4.45 0.37 1.87e-5 Myopia (pathological); TGCT cis rs35146811 0.735 rs858505 chr7:99819577 G/A cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs1843834 0.539 rs12694643 chr2:225446603 A/G cg12698349 chr2:225449008 CUL3 0.82 6.88 0.53 2.68e-10 IgE levels in asthmatics (D.p. specific); TGCT cis rs9486715 0.867 rs9480700 chr6:96965056 A/G cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs2996428 0.601 rs10909804 chr1:3770929 A/G cg17848003 chr1:3704513 LRRC47 -0.18 -5.15 -0.42 9.99e-7 Red cell distribution width; TGCT cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.67 -0.39 7.79e-6 Bipolar disorder; TGCT cis rs6570726 0.791 rs9376953 chr6:145912226 G/T cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7523050 0.554 rs34086470 chr1:109485991 C/A cg08274380 chr1:109419600 GPSM2 1.12 6.19 0.49 8.06e-9 Fat distribution (HIV); TGCT cis rs6977940 0.818 rs73033460 chr7:2900662 C/T cg19731401 chr7:2775893 GNA12 0.38 4.61 0.38 9.91e-6 White matter integrity; TGCT cis rs17401966 0.931 rs11584023 chr1:10302596 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.6 -0.38 1.02e-5 Hepatocellular carcinoma; TGCT cis rs9325144 0.752 rs12300353 chr12:39154492 G/C cg13010199 chr12:38710504 ALG10B -0.52 -4.63 -0.38 9.18e-6 Morning vs. evening chronotype; TGCT cis rs4478037 0.822 rs9875140 chr3:33117068 T/A cg19404215 chr3:33155277 CRTAP 1.27 6.16 0.48 9.36e-9 Major depressive disorder; TGCT cis rs13191362 1.000 rs35820211 chr6:163046252 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.5 0.61 5.17e-14 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9611565 0.608 rs2003816 chr22:42095140 T/G cg17554472 chr22:41940697 POLR3H 0.46 4.91 0.4 2.82e-6 Vitiligo; TGCT cis rs2180341 0.640 rs11154395 chr6:127629138 T/C cg24812749 chr6:127587940 RNF146 0.64 5.4 0.44 3.31e-7 Breast cancer; TGCT cis rs826838 1.000 rs1684395 chr12:39083161 T/G cg26384229 chr12:38710491 ALG10B -0.85 -8.09 -0.59 4.68e-13 Heart rate; TGCT cis rs7605378 0.528 rs281791 chr2:200850402 A/G cg23649088 chr2:200775458 C2orf69 -0.46 -9.85 -0.66 2.88e-17 Osteoporosis; TGCT cis rs6604026 0.656 rs2255723 chr1:93368309 A/C cg17283838 chr1:93427260 FAM69A 0.56 4.44 0.37 1.96e-5 Multiple sclerosis; TGCT cis rs7017914 0.905 rs2956610 chr8:71929533 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs7829975 0.533 rs1039917 chr8:8718850 C/T cg08975724 chr8:8085496 FLJ10661 0.53 4.76 0.39 5.28e-6 Mood instability; TGCT cis rs61774743 0.754 rs11578963 chr1:41834183 A/G cg01193554 chr1:41846683 NA 0.43 5.36 0.43 3.91e-7 Intelligence (multi-trait analysis); TGCT cis rs425277 1.000 rs55826501 chr1:2059143 G/A cg03732007 chr1:2071316 PRKCZ 0.25 5.0 0.41 1.92e-6 Height; TGCT cis rs478304 0.651 rs11537193 chr11:65500003 A/C cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.05e-10 Acne (severe); TGCT cis rs2404602 0.716 rs17461634 chr15:76764107 G/A cg22467129 chr15:76604101 ETFA -0.55 -6.71 -0.52 6.26e-10 Blood metabolite levels; TGCT cis rs748404 0.660 rs2444251 chr15:43788595 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.71 0.39 6.47e-6 Lung cancer; TGCT cis rs2050392 0.789 rs303438 chr10:30733493 C/T cg13289132 chr10:30722225 MAP3K8 0.4 4.97 0.41 2.21e-6 Inflammatory bowel disease; TGCT cis rs13082711 0.863 rs66743193 chr3:27471958 G/A cg02860705 chr3:27208620 NA 0.35 4.83 0.4 3.9e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2404602 0.622 rs9635380 chr15:77103479 A/G cg22467129 chr15:76604101 ETFA 0.47 4.65 0.39 8.39e-6 Blood metabolite levels; TGCT trans rs1496653 0.602 rs13085173 chr3:23605263 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs6988636 1.000 rs11993411 chr8:124180537 T/C cg23067535 chr8:124195133 FAM83A -0.34 -5.13 -0.42 1.09e-6 Urinary uromodulin levels; TGCT trans rs4650994 0.507 rs56229230 chr1:178526563 G/A cg05059571 chr16:84539110 KIAA1609 -0.54 -11.05 -0.7 3.58e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs36051895 0.664 rs11788834 chr9:5092466 G/A cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs7528419 1.000 rs646776 chr1:109818530 C/T cg00908766 chr1:109817496 CELSR2 0.52 5.36 0.43 4e-7 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs7666738 1.000 rs880473 chr4:98922596 C/T cg17366294 chr4:99064904 C4orf37 0.8 7.2 0.54 5.04e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10779751 0.690 rs2791646 chr1:11133242 C/T cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs6121246 0.559 rs6060919 chr20:30331922 A/T cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs9311474 0.607 rs28661185 chr3:52567188 G/T cg10802521 chr3:52805072 NEK4 -0.73 -9.09 -0.63 2.03e-15 Electroencephalogram traits; TGCT cis rs2153535 0.526 rs1796689 chr6:8536433 A/C cg07606381 chr6:8435919 SLC35B3 0.54 4.83 0.4 3.9e-6 Motion sickness; TGCT cis rs72615157 0.561 rs113844570 chr7:99873778 A/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.69 5.32 0.43 4.67e-7 Lung function (FEV1/FVC); TGCT cis rs9902453 0.933 rs4470197 chr17:28464474 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.08e-7 Coffee consumption (cups per day); TGCT cis rs2204008 0.744 rs11514358 chr12:38255526 G/A cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs7586879 0.662 rs2384059 chr2:25100338 C/T cg15423357 chr2:25149977 NA 0.5 4.75 0.39 5.43e-6 Body mass index; TGCT cis rs137603 0.644 rs94852 chr22:39712334 T/C cg01093212 chr22:39715156 SNORD43;RPL3 -0.51 -4.98 -0.41 2.09e-6 Primary biliary cholangitis; TGCT cis rs11190604 1.000 rs7078799 chr10:102301447 G/A cg16342193 chr10:102329863 NA -0.4 -4.97 -0.41 2.14e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs782590 0.837 rs809732 chr2:55914621 T/C cg18811423 chr2:55921094 PNPT1 0.7 7.83 0.58 1.88e-12 Metabolic syndrome; TGCT cis rs7666738 0.753 rs13111199 chr4:98953705 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs739401 0.572 rs739400 chr11:3016520 G/A cg05729581 chr11:3078854 CARS -0.59 -5.39 -0.44 3.47e-7 Longevity; TGCT cis rs11122272 0.705 rs2486742 chr1:231507254 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs3784262 0.565 rs12914414 chr15:58318757 T/C cg12031962 chr15:58353849 ALDH1A2 -0.39 -5.63 -0.45 1.16e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg15687855 chr3:44754131 ZNF502 -0.43 -5.23 -0.42 7.08e-7 Depressive symptoms; TGCT cis rs12188164 0.515 rs11744936 chr5:412112 C/T cg26850624 chr5:429559 AHRR -0.2 -4.45 -0.37 1.9e-5 Cystic fibrosis severity; TGCT cis rs1215050 0.791 rs1215054 chr4:98863009 T/G cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1371867 0.846 rs924057 chr8:101266157 A/G cg00191853 chr8:101177733 SPAG1 0.23 4.8 0.4 4.44e-6 Atrioventricular conduction; TGCT cis rs9902453 1.000 rs7223786 chr17:28332107 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs7267979 0.834 rs6115100 chr20:25225938 C/A cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7635838 0.539 rs430353 chr3:11254071 G/A cg00170343 chr3:11313890 ATG7 0.58 5.5 0.44 2.11e-7 HDL cholesterol; TGCT cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.56 4.9 0.4 2.92e-6 Height; TGCT trans rs1814175 0.566 rs1811673 chr11:49602134 A/G cg11707556 chr5:10655725 ANKRD33B -0.4 -7.77 -0.57 2.55e-12 Height; TGCT cis rs2075371 0.501 rs1646654 chr7:134027547 G/C cg11752832 chr7:134001865 SLC35B4 0.59 5.09 0.42 1.31e-6 Mean platelet volume; TGCT cis rs7267979 0.932 rs1985737 chr20:25591468 T/A cg03522245 chr20:25566470 NINL 0.6 6.47 0.5 2.1e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs797680 0.930 rs12128131 chr1:93546299 T/G cg17826107 chr1:92977322 EVI5 -0.21 -4.78 -0.39 4.89e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs4975709 0.569 rs2077269 chr5:1863506 C/T cg12288994 chr5:1860383 NA 0.24 4.65 0.39 8.32e-6 Cardiovascular disease risk factors; TGCT cis rs911263 0.540 rs7158493 chr14:68812330 C/G cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs7808935 0.768 rs757138 chr7:27989403 T/G cg00453374 chr7:27701825 HIBADH -0.45 -4.47 -0.37 1.72e-5 Prostate cancer; TGCT cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg17264618 chr3:40429014 ENTPD3 0.33 4.71 0.39 6.47e-6 Renal cell carcinoma; TGCT cis rs2964802 0.505 rs13180011 chr5:10824615 T/C cg14521931 chr5:10832172 NA -0.28 -4.71 -0.39 6.44e-6 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg17546649 chr3:44802566 KIF15;KIAA1143 -0.36 -4.44 -0.37 1.99e-5 Depressive symptoms; TGCT cis rs7605378 0.752 rs769960 chr2:200710706 G/T cg19045956 chr2:200819837 C2orf60;C2orf47 -0.48 -4.65 -0.39 8.51e-6 Osteoporosis; TGCT cis rs3812831 0.669 rs382913 chr13:114928255 G/T cg06611532 chr13:114900021 NA 0.35 6.26 0.49 5.63e-9 Schizophrenia; TGCT cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs483180 0.532 rs561931 chr1:120254506 A/G cg19096424 chr1:120255104 PHGDH 0.62 5.66 0.45 9.8e-8 Macular telangiectasia type 2; TGCT cis rs854765 0.693 rs4924822 chr17:17748013 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.46 -0.5 2.17e-9 Total body bone mineral density; TGCT cis rs3824867 0.920 rs7105122 chr11:47449544 A/G cg20307385 chr11:47447363 PSMC3 0.66 5.68 0.45 9.16e-8 Mean corpuscular hemoglobin; TGCT cis rs1552244 1.000 rs7652935 chr3:10151138 T/C cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs40363 0.645 rs250629 chr16:3525431 C/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.62 -4.57 -0.38 1.14e-5 Tuberculosis; TGCT cis rs1805008 0.561 rs8046635 chr16:90123493 C/T cg08547343 chr16:90038815 CENPBD1;AFG3L1 -0.77 -4.45 -0.37 1.89e-5 Skin colour saturation; TGCT cis rs4077468 0.927 rs1342063 chr1:205912859 C/T cg24503407 chr1:205819492 PM20D1 -0.39 -4.61 -0.38 1e-5 Cystic fibrosis-related diabetes; TGCT cis rs2404602 0.735 rs11638767 chr15:76655938 T/C cg22467129 chr15:76604101 ETFA 0.45 4.57 0.38 1.14e-5 Blood metabolite levels; TGCT cis rs6754311 0.593 rs313518 chr2:136439090 C/T cg07169764 chr2:136633963 MCM6 0.63 5.62 0.45 1.19e-7 Mosquito bite size; TGCT cis rs916888 0.773 rs199535 chr17:44822662 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.8 5.54 0.45 1.72e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2153535 0.580 rs7767926 chr6:8453557 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs854765 0.693 rs35451946 chr17:17764061 C/G cg04398451 chr17:18023971 MYO15A 0.28 4.51 0.38 1.49e-5 Total body bone mineral density; TGCT cis rs7647973 0.922 rs57273516 chr3:49483074 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.53 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs9303401 0.659 rs72828726 chr17:56951217 C/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7727544 0.647 rs72793280 chr5:131562900 C/T cg24060327 chr5:131705240 SLC22A5 -0.55 -5.12 -0.42 1.14e-6 Blood metabolite levels; TGCT cis rs12142240 0.920 rs6697623 chr1:46757542 G/A cg00530320 chr1:46809349 NSUN4 0.25 4.81 0.4 4.3e-6 Menopause (age at onset); TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs2456568 1.000 rs2456568 chr11:93691332 A/T cg17595323 chr11:93583763 C11orf90 -0.46 -6.1 -0.48 1.25e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4730250 0.581 rs3779500 chr7:106792704 T/C cg02696742 chr7:106810147 HBP1 0.72 5.89 0.47 3.44e-8 Osteoarthritis; TGCT cis rs12210905 0.925 rs12193820 chr6:27113811 A/G cg08851530 chr6:28072375 NA 1.08 5.25 0.43 6.28e-7 Hip circumference adjusted for BMI; TGCT cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg11644478 chr21:40555479 PSMG1 1.03 11.12 0.71 2.32e-20 Cognitive function; TGCT cis rs78487399 0.808 rs75126888 chr2:43664007 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7617773 0.743 rs11716371 chr3:48362750 C/T cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs3820928 0.839 rs12470666 chr2:227876525 G/A cg11843606 chr2:227700838 RHBDD1 -0.55 -4.83 -0.4 3.97e-6 Pulmonary function; TGCT cis rs2075371 0.932 rs2598290 chr7:133987736 C/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs302668 0.651 rs12295227 chr11:87870556 C/A cg01568784 chr11:87908783 RAB38 0.34 4.52 0.38 1.4e-5 Frontotemporal dementia; TGCT cis rs7208859 0.623 rs9912440 chr17:29148772 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs875971 1.000 rs4718357 chr7:65960878 A/G cg11764359 chr7:65958608 NA 0.63 5.68 0.45 8.88e-8 Aortic root size; TGCT cis rs9916302 0.904 rs2061338 chr17:37421767 T/C cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT trans rs7618501 0.699 rs11713193 chr3:49924424 G/A cg21659725 chr3:3221576 CRBN 0.76 8.86 0.62 6.99e-15 Intelligence (multi-trait analysis); TGCT cis rs12765878 0.967 rs11598018 chr10:105661315 C/A cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs6121246 0.909 rs6060679 chr20:30270772 C/G cg18721089 chr20:30220636 NA 0.42 4.65 0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs769267 0.930 rs4808957 chr19:19567248 A/G cg08509172 chr19:19383838 TM6SF2 -0.35 -4.6 -0.38 1.02e-5 Tonsillectomy; TGCT cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg13770153 chr20:60521292 NA 0.6 8.67 0.61 2.02e-14 Obesity-related traits; TGCT cis rs7647973 0.925 rs7429661 chr3:49228800 G/A cg05785598 chr3:49045655 WDR6 0.39 4.69 0.39 7.2e-6 Menarche (age at onset); TGCT trans rs66573146 1.000 rs56178503 chr4:6961748 C/T cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs5769765 0.874 rs4624 chr22:50281917 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.07 -0.48 1.46e-8 Schizophrenia; TGCT cis rs7824557 0.545 rs34482136 chr8:11227885 C/T cg21775007 chr8:11205619 TDH -0.59 -5.48 -0.44 2.29e-7 Retinal vascular caliber; TGCT cis rs9682041 0.877 rs10755126 chr3:170071694 C/G cg07589077 chr3:170072950 NA -0.29 -5.06 -0.41 1.48e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs947211 0.898 rs10900524 chr1:205748309 G/A cg14893161 chr1:205819251 PM20D1 0.43 4.44 0.37 1.96e-5 Parkinson's disease; TGCT cis rs9810089 0.903 rs7432375 chr3:136288405 G/A cg12473912 chr3:136751656 NA 0.34 4.83 0.4 3.9e-6 Gestational age at birth (child effect); TGCT cis rs6964587 1.000 rs28927678 chr7:91715662 C/T cg22709100 chr7:91322751 NA 0.28 4.69 0.39 6.96e-6 Breast cancer; TGCT cis rs10465746 0.682 rs55693838 chr1:84359081 G/A cg10977910 chr1:84465055 TTLL7 0.65 6.37 0.5 3.39e-9 Obesity-related traits; TGCT cis rs9894429 0.505 rs35570626 chr17:79611084 A/G cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs7086627 0.515 rs2125040 chr10:82208422 G/C cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs79387448 0.614 rs6719130 chr2:102958236 C/T cg09003973 chr2:102972529 NA 1.34 10.63 0.69 3.78e-19 Gut microbiota (bacterial taxa); TGCT cis rs1348850 0.567 rs880899 chr2:178532416 A/G cg22681709 chr2:178499509 PDE11A -0.47 -5.94 -0.47 2.69e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs295140 0.605 rs159320 chr2:201187775 A/G cg04283868 chr2:201171347 SPATS2L -0.47 -4.45 -0.37 1.87e-5 QT interval; TGCT cis rs4819052 0.765 rs2838854 chr21:46680364 A/G cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg11494091 chr17:61959527 GH2 0.6 14.37 0.79 3.65e-28 Prudent dietary pattern; TGCT cis rs1215050 0.904 rs165246 chr4:98688541 C/T cg05340658 chr4:99064831 C4orf37 0.44 4.67 0.39 7.64e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4689388 0.926 rs10937719 chr4:6295322 C/G cg14416269 chr4:6271139 WFS1 0.42 5.43 0.44 2.91e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs826838 1.000 rs11168505 chr12:38939057 A/T cg26384229 chr12:38710491 ALG10B -0.81 -7.45 -0.56 1.38e-11 Heart rate; TGCT cis rs6429082 0.667 rs10802800 chr1:235706283 A/G cg26050004 chr1:235667680 B3GALNT2 -0.55 -4.63 -0.38 9.13e-6 Adiposity; TGCT cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg27211696 chr2:191398769 TMEM194B 0.28 5.2 0.42 8.06e-7 Pulse pressure; TGCT cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg03303774 chr4:1407052 NA 0.32 4.73 0.39 6.03e-6 Obesity-related traits; TGCT cis rs950169 0.580 rs35516100 chr15:85195430 C/T cg17173187 chr15:85201210 NMB 0.59 6.75 0.52 5.05e-10 Schizophrenia; TGCT cis rs1406084 0.636 rs6750165 chr2:154727830 T/C cg25703346 chr2:154729189 GALNT13 0.79 4.63 0.38 9.04e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2427308 0.643 rs477859 chr20:60937597 A/G cg06026331 chr20:60912101 LAMA5 -0.29 -4.65 -0.39 8.25e-6 Colorectal cancer; TGCT cis rs68170813 0.523 rs3757713 chr7:107042750 A/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs263156 1.000 rs839554 chr6:142907051 T/C cg18419694 chr6:143832440 FUCA2 -0.4 -4.65 -0.39 8.22e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs7104764 1.000 rs6598074 chr11:219398 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 10.47 0.69 8.98e-19 Menarche (age at onset); TGCT cis rs13191362 0.507 rs2846536 chr6:163033492 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.61 5.87 0.47 3.79e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7178424 0.606 rs1000598 chr15:62141611 G/C cg00456672 chr15:62358751 C2CD4A -0.29 -4.51 -0.38 1.51e-5 Height; TGCT cis rs4733781 0.865 rs17284725 chr8:131282724 A/T cg16277922 chr8:131349729 ASAP1 0.38 4.82 0.4 4.05e-6 Tuberculosis; TGCT cis rs6570726 0.935 rs1883406 chr6:145823205 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs4650994 1.000 rs17361251 chr1:178520577 C/A cg05059571 chr16:84539110 KIAA1609 -0.41 -7.6 -0.56 6.42e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7474896 0.583 rs10740950 chr10:38003496 C/T cg25427524 chr10:38739819 LOC399744 -0.34 -5.47 -0.44 2.43e-7 Obesity (extreme); TGCT cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg07061783 chr6:25882402 NA -0.47 -4.95 -0.41 2.37e-6 Blood metabolite levels; TGCT cis rs1577917 0.958 rs2660576 chr6:86651603 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs7539409 0.651 rs979757 chr1:84296605 T/C cg10977910 chr1:84465055 TTLL7 0.9 5.47 0.44 2.39e-7 Alzheimer's disease; TGCT cis rs9457247 0.967 rs2149083 chr6:167370971 G/C cg23791538 chr6:167370224 RNASET2 0.51 4.98 0.41 2.09e-6 Crohn's disease; TGCT cis rs2836974 0.932 rs56306759 chr21:40608106 G/A cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.3e-9 Cognitive function; TGCT cis rs1949733 0.523 rs55977448 chr4:8542918 G/T cg13073564 chr4:8508604 NA 0.5 4.9 0.4 2.96e-6 Response to antineoplastic agents; TGCT cis rs2594989 0.943 rs2454512 chr3:11487506 A/G cg00170343 chr3:11313890 ATG7 0.69 5.1 0.42 1.26e-6 Circulating chemerin levels; TGCT cis rs9894429 0.809 rs9889642 chr17:79591762 T/C cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs12142240 0.698 rs56358525 chr1:46849520 C/T cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs7666738 0.962 rs17027204 chr4:98997049 G/A cg17366294 chr4:99064904 C4orf37 0.69 6.39 0.5 3.1e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs62064224 0.703 rs62065493 chr17:30822620 C/G cg18200150 chr17:30822561 MYO1D 0.57 8.04 0.59 6.08e-13 Schizophrenia; TGCT cis rs12220898 0.679 rs10857458 chr10:50477906 A/G cg06072769 chr10:50146962 WDFY4 0.35 4.5 0.37 1.56e-5 Inflammatory biomarkers; TGCT cis rs1401999 1.000 rs2176824 chr3:183654029 C/G cg01324343 chr3:183735012 ABCC5 0.85 11.33 0.71 7.12e-21 Anterior chamber depth; TGCT cis rs3820068 0.608 rs6668919 chr1:16049893 A/G cg05660106 chr1:15850417 CASP9 -0.72 -6.7 -0.52 6.62e-10 Systolic blood pressure; TGCT cis rs1008375 0.932 rs2302394 chr4:17641188 A/G cg16339924 chr4:17578868 LAP3 0.66 5.52 0.44 1.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.830 rs2114426 chr4:98933130 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28735056 0.609 rs4799099 chr18:77639585 A/G cg20368463 chr18:77673604 PQLC1 0.45 5.5 0.44 2.04e-7 Schizophrenia; TGCT cis rs73384572 1.000 rs2123421 chr10:130931444 G/T cg00886512 chr10:131637291 EBF3 0.4 4.57 0.38 1.15e-5 Neuroticism; TGCT cis rs10782582 0.586 rs11161902 chr1:76392498 C/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.56 4.84 0.4 3.71e-6 Daytime sleep phenotypes; TGCT cis rs7666738 0.546 rs13105521 chr4:98734419 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.57 0.45 1.5e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2832191 0.935 rs11910475 chr21:30519702 T/C cg08807101 chr21:30365312 RNF160 -0.54 -5.02 -0.41 1.78e-6 Dental caries; TGCT cis rs6089584 0.888 rs6061982 chr20:60620673 C/T cg13770153 chr20:60521292 NA -0.54 -7.12 -0.54 7.73e-11 Body mass index; TGCT cis rs1862618 0.671 rs2591968 chr5:56233541 A/G cg20203395 chr5:56204925 C5orf35 -0.51 -4.65 -0.39 8.42e-6 Initial pursuit acceleration; TGCT cis rs7017914 0.905 rs2732094 chr8:71919918 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs526231 0.578 rs59323174 chr5:102267869 T/C cg23492399 chr5:102201601 PAM -0.51 -4.51 -0.38 1.47e-5 Primary biliary cholangitis; TGCT cis rs2404602 0.598 rs11855999 chr15:76627333 A/C cg22467129 chr15:76604101 ETFA 0.51 4.97 0.41 2.16e-6 Blood metabolite levels; TGCT cis rs2594989 0.831 rs7651790 chr3:11572610 C/T cg26283222 chr3:11613257 VGLL4 0.2 4.45 0.37 1.89e-5 Circulating chemerin levels; TGCT cis rs265548 0.646 rs36692 chr19:17906839 C/T cg21960279 chr19:17905606 B3GNT3 0.48 5.41 0.44 3.15e-7 Tumor biomarkers; TGCT cis rs28595532 0.844 rs116721336 chr4:119536538 A/G cg21605333 chr4:119757512 SEC24D 1.33 8.01 0.58 7.07e-13 Cannabis dependence symptom count; TGCT cis rs1062177 0.547 rs2915818 chr5:151115290 T/A cg12924095 chr5:151150029 G3BP1 -0.33 -4.82 -0.4 4.07e-6 Preschool internalizing problems; TGCT cis rs3733585 0.673 rs7375587 chr4:9954758 A/T cg00071950 chr4:10020882 SLC2A9 0.54 6.36 0.5 3.54e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7208859 0.623 rs8080882 chr17:29081146 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs763014 0.932 rs2384975 chr16:651115 G/T cg27436995 chr16:743998 FBXL16 -0.46 -5.08 -0.42 1.35e-6 Height; TGCT cis rs9549367 0.789 rs3850451 chr13:113905812 C/G cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs13191362 0.507 rs6936804 chr6:163069424 A/T cg21926612 chr6:163149169 PACRG;PARK2 -0.6 -5.24 -0.43 6.77e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1153858 1.000 rs16942568 chr15:45677390 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs2338224 1.000 rs12697710 chr5:71747245 T/A cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs1215050 0.740 rs700740 chr4:98976003 A/C cg05340658 chr4:99064831 C4orf37 -0.43 -5.27 -0.43 5.8e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3809566 1.000 rs4775610 chr15:63332057 C/T cg05507819 chr15:63340323 TPM1 -0.49 -4.57 -0.38 1.16e-5 Platelet count; TGCT cis rs7937682 0.889 rs493810 chr11:111491888 G/T cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs7647973 0.696 rs7100 chr3:49053219 A/G cg07636037 chr3:49044803 WDR6 0.81 6.68 0.51 7.37e-10 Menarche (age at onset); TGCT cis rs597539 0.652 rs584108 chr11:68630282 A/T cg04772025 chr11:68637568 NA -0.61 -6.86 -0.52 2.95e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9926296 0.509 rs2159113 chr16:89832083 C/T cg21285383 chr16:89894308 SPIRE2 0.43 6.48 0.5 1.93e-9 Vitiligo; TGCT cis rs1153858 0.943 rs8038342 chr15:45651537 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs11696501 0.739 rs6073843 chr20:44293956 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs4886920 0.573 rs11854573 chr15:78108112 C/A cg25212270 chr15:78015279 NA 0.24 4.62 0.38 9.48e-6 Neuroticism; TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg25703541 chr22:24373054 LOC391322 -0.81 -8.7 -0.62 1.68e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6089829 0.925 rs6062396 chr20:61667949 T/C cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467773 1.000 rs1535277 chr6:26567802 G/T cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs6728302 0.557 rs73001973 chr2:233241575 G/A cg06555452 chr2:233241558 NA 0.37 4.99 0.41 2.01e-6 Height; TGCT cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.69e-9 Blood metabolite levels; TGCT cis rs9325144 0.624 rs10506126 chr12:39123244 G/A cg10518543 chr12:38710700 ALG10B -0.48 -4.44 -0.37 1.94e-5 Morning vs. evening chronotype; TGCT cis rs11690935 1.000 rs34542126 chr2:172542705 C/T cg13550731 chr2:172543902 DYNC1I2 1.2 12.95 0.76 8.62e-25 Schizophrenia; TGCT cis rs10972341 1.000 rs7856842 chr9:35145157 C/T cg00812861 chr9:35114699 KIAA1539 0.33 5.0 0.41 1.88e-6 Weight; TGCT cis rs2228479 0.850 rs2238527 chr16:89840708 C/A cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs4808199 0.842 rs11085259 chr19:19445856 C/T cg03709012 chr19:19516395 GATAD2A 0.81 6.32 0.49 4.32e-9 Nonalcoholic fatty liver disease; TGCT cis rs7552404 0.883 rs7513363 chr1:76143443 A/G cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.830 rs6851253 chr4:99029980 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9322193 0.923 rs9766886 chr6:149958184 T/C cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs9302065 0.681 rs59108692 chr13:95962424 C/A cg26751094 chr13:95954534 ABCC4 -0.33 -5.31 -0.43 4.91e-7 Blood metabolite levels; TGCT cis rs7192750 0.517 rs9932922 chr16:71918178 T/C cg06353428 chr16:71660113 MARVELD3 0.82 7.26 0.55 3.82e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs5769765 0.954 rs5770709 chr22:50245196 G/T cg22709217 chr22:50311962 ALG12;CRELD2 1.08 11.84 0.73 4.29e-22 Schizophrenia; TGCT cis rs11118844 0.696 rs11118859 chr1:221953193 A/T cg04222084 chr1:221915650 DUSP10 -0.78 -4.66 -0.39 8.03e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs79387448 0.745 rs9677607 chr2:103149520 A/T cg09003973 chr2:102972529 NA 0.97 6.32 0.49 4.33e-9 Gut microbiota (bacterial taxa); TGCT cis rs2073300 1.000 rs6137984 chr20:23469864 T/A cg09953122 chr20:23471693 CST8 -0.7 -4.76 -0.39 5.31e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT trans rs28735056 0.967 rs11660941 chr18:77630600 G/C cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT cis rs7208859 0.623 rs11652533 chr17:29060601 A/C cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4242434 0.597 rs1877675 chr8:22533947 C/T cg21658235 chr8:22456391 C8orf58 -0.45 -4.74 -0.39 5.8e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7044106 0.791 rs7036196 chr9:123479457 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.85 0.4 3.57e-6 Hip circumference adjusted for BMI; TGCT cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg10117171 chr1:25599238 RHD 0.35 5.71 0.46 7.87e-8 Erythrocyte sedimentation rate; TGCT cis rs7666738 0.791 rs11729596 chr4:99045461 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7582180 0.606 rs11684004 chr2:100954783 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs9649213 0.614 rs4729432 chr7:97947055 G/C cg09267113 chr7:98030324 BAIAP2L1 -0.94 -8.69 -0.62 1.83e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs9291683 0.530 rs11723970 chr4:9980462 T/C cg00071950 chr4:10020882 SLC2A9 0.65 8.23 0.59 2.21e-13 Bone mineral density; TGCT cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs259282 0.563 rs596394 chr19:33111162 T/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.73 7.36 0.55 2.2e-11 Schizophrenia; TGCT cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.76e-15 Bipolar disorder; TGCT cis rs4665809 0.525 rs4665324 chr2:26447147 A/C cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs2836974 0.897 rs35123057 chr21:40711689 C/T cg11644478 chr21:40555479 PSMG1 0.88 8.03 0.59 6.26e-13 Cognitive function; TGCT cis rs6665290 0.835 rs7549465 chr1:227214399 A/C cg10327440 chr1:227177885 CDC42BPA -0.92 -16.53 -0.83 3.84e-33 Myeloid white cell count; TGCT cis rs4970988 0.501 rs11204713 chr1:150694623 T/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Urate levels; TGCT cis rs17030434 1.000 rs10026531 chr4:154727070 C/T cg14289246 chr4:154710475 SFRP2 -0.88 -6.96 -0.53 1.78e-10 Electrocardiographic conduction measures; TGCT cis rs1570884 0.890 rs6561541 chr13:50127280 C/T cg08779649 chr13:50194554 NA 0.32 4.78 0.39 4.77e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs9581857 0.685 rs9319369 chr13:28042323 A/T cg22138327 chr13:27999177 GTF3A 0.72 4.6 0.38 1.03e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7552404 0.628 rs5745442 chr1:76342858 T/G cg22875332 chr1:76189707 ACADM 0.68 6.91 0.53 2.23e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17376456 1.000 rs6867042 chr5:93555761 C/T cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.72e-12 Diabetic retinopathy; TGCT cis rs4642101 0.534 rs13316229 chr3:12807371 C/T cg05775895 chr3:12838266 CAND2 0.51 5.11 0.42 1.16e-6 QRS complex (12-leadsum); TGCT cis rs892961 0.836 rs35077273 chr17:75412415 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs1218582 0.772 rs2335408 chr1:154915977 G/A cg09359103 chr1:154839909 KCNN3 -0.63 -11.36 -0.71 6.16e-21 Prostate cancer; TGCT cis rs394563 0.591 rs237035 chr6:149710848 C/T cg03678062 chr6:149772716 ZC3H12D -0.38 -4.74 -0.39 5.87e-6 Dupuytren's disease; TGCT cis rs2658782 0.724 rs2658769 chr11:93252030 T/C cg15737290 chr11:93063684 CCDC67 0.63 4.72 0.39 6.22e-6 Pulmonary function decline; TGCT cis rs6952808 0.929 rs12667688 chr7:1931030 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.77 -0.46 6.08e-8 Bipolar disorder and schizophrenia; TGCT cis rs875971 1.000 rs12532998 chr7:65967459 A/C cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs682748 0.846 rs13178413 chr5:17151456 G/A cg23987134 chr5:17158319 LOC285696 -0.22 -5.4 -0.44 3.21e-7 Hippocampal atrophy; TGCT cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg13395646 chr4:1353034 KIAA1530 -0.36 -4.45 -0.37 1.91e-5 Obesity-related traits; TGCT cis rs1371867 0.839 rs1788186 chr8:101335686 T/C cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs524281 0.684 rs7946447 chr11:65864338 T/C cg00563793 chr11:65837595 PACS1 0.55 4.64 0.38 8.89e-6 Electroencephalogram traits; TGCT cis rs7267979 0.966 rs6050567 chr20:25354561 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12142240 0.698 rs6697123 chr1:46811310 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs7746199 0.736 rs6904596 chr6:27491299 G/A cg10876282 chr6:28092338 ZSCAN16 0.87 4.72 0.39 6.19e-6 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs9388451 0.537 rs1739383 chr6:126098915 G/T cg05901451 chr6:126070800 HEY2 -0.94 -11.89 -0.73 3.1e-22 Brugada syndrome; TGCT cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg13695892 chr22:41940480 POLR3H 0.79 7.51 0.56 9.92e-12 Vitiligo; TGCT trans rs561341 0.883 rs4450460 chr17:30201309 C/T cg20587970 chr11:113659929 NA 0.8 9.3 0.64 6.34e-16 Hip circumference adjusted for BMI; TGCT cis rs2549003 0.811 rs10035166 chr5:131823927 C/T cg02551604 chr5:131831745 NA 0.66 7.02 0.53 1.27e-10 Asthma (sex interaction); TGCT cis rs7772486 0.713 rs1986729 chr6:146194831 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.06 0.41 1.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.875 rs2748497 chr6:146319417 C/T cg23711669 chr6:146136114 FBXO30 0.8 8.06 0.59 5.4e-13 Lobe attachment (rater-scored or self-reported); TGCT cis rs769267 1.000 rs3764567 chr19:19440066 C/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.55 -4.56 -0.38 1.22e-5 Tonsillectomy; TGCT cis rs13242816 1.000 rs1049334 chr7:116200380 A/G cg02799643 chr7:116139180 CAV2 0.45 5.67 0.45 9.71e-8 P wave duration; TGCT cis rs2458413 0.500 rs2458418 chr8:105350851 A/G cg04554929 chr8:105342491 NA 0.52 6.13 0.48 1.1e-8 Paget's disease; TGCT cis rs4689388 0.890 rs6446481 chr4:6295583 C/A cg00701064 chr4:6280414 WFS1 0.39 4.78 0.39 4.97e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7264396 0.616 rs6060744 chr20:34581555 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.96 -0.41 2.25e-6 Total cholesterol levels; TGCT cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg11494091 chr17:61959527 GH2 0.6 13.05 0.76 5.09e-25 Prudent dietary pattern; TGCT cis rs9549260 0.712 rs1334241 chr13:41223110 C/T cg21288729 chr13:41239152 FOXO1 0.69 4.87 0.4 3.31e-6 Red blood cell count; TGCT cis rs2549003 1.000 rs7701588 chr5:131819970 T/C cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.92e-6 Asthma (sex interaction); TGCT cis rs6570726 0.791 rs6570693 chr6:145910841 C/T cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.846 rs2492856 chr6:146323928 A/G cg23711669 chr6:146136114 FBXO30 0.82 8.92 0.63 5.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs9900497 0.504 rs2228100 chr17:19642952 C/G cg15323506 chr17:19619410 SLC47A2 0.19 4.91 0.4 2.86e-6 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg26513180 chr16:89883248 FANCA 0.74 7.25 0.55 3.87e-11 Vitiligo; TGCT cis rs7926906 1.000 rs10734138 chr11:90538063 A/C cg26138821 chr11:89956704 CHORDC1 -0.51 -5.39 -0.44 3.46e-7 Intelligence (multi-trait analysis); TGCT trans rs9650657 0.501 rs3021500 chr8:11023997 G/C cg06636001 chr8:8085503 FLJ10661 -0.83 -7.83 -0.58 1.84e-12 Neuroticism; TGCT cis rs12497850 0.931 rs13316620 chr3:49045355 T/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.51 0.44 2e-7 Parkinson's disease; TGCT cis rs9383153 0.625 rs1886349 chr6:16320320 G/A cg14009473 chr6:15502099 JARID2 0.68 5.14 0.42 1.03e-6 Gambling; TGCT cis rs12497850 0.931 rs9755490 chr3:48871664 A/C cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs7000551 0.689 rs6984908 chr8:22316901 A/G cg12081754 chr8:22256438 SLC39A14 -0.29 -4.89 -0.4 3.01e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1372520 0.684 rs184810 chr4:90697979 T/C cg20003494 chr4:90757398 SNCA 0.56 4.46 0.37 1.83e-5 Neuroticism; TGCT cis rs1997103 0.911 rs9642575 chr7:55399090 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7940866 0.774 rs12420126 chr11:130834811 C/T cg12179176 chr11:130786555 SNX19 0.61 5.72 0.46 7.47e-8 Schizophrenia; TGCT cis rs9926296 0.572 rs8047581 chr16:89884502 C/T cg26513180 chr16:89883248 FANCA 0.75 7.67 0.57 4.42e-12 Vitiligo; TGCT cis rs12477438 0.798 rs4851179 chr2:99568774 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.73 -6.46 -0.5 2.2e-9 Chronic sinus infection; TGCT cis rs13256369 1.000 rs4840351 chr8:8573148 A/G cg18904891 chr8:8559673 CLDN23 0.62 5.67 0.45 9.47e-8 Obesity-related traits; TGCT cis rs9611565 0.879 rs5758311 chr22:41759375 G/T cg06481639 chr22:41940642 POLR3H -0.58 -5.01 -0.41 1.81e-6 Vitiligo; TGCT trans rs2727020 0.521 rs10839285 chr11:49496852 T/G cg03929089 chr4:120376271 NA 0.63 6.88 0.53 2.59e-10 Coronary artery disease; TGCT cis rs2046867 0.862 rs6788139 chr3:72835630 A/G cg25664220 chr3:72788482 NA 0.49 6.52 0.51 1.57e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4803468 0.935 rs13346603 chr19:41945837 T/A cg09537434 chr19:41945824 ATP5SL 0.91 10.11 0.67 6.81e-18 Height; TGCT cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg10263370 chr3:44754102 ZNF502 0.45 5.35 0.43 4.08e-7 Depressive symptoms; TGCT cis rs12142240 0.731 rs6681857 chr1:46850124 T/C cg14993813 chr1:46806288 NSUN4 -0.59 -4.9 -0.4 2.94e-6 Menopause (age at onset); TGCT cis rs265548 0.608 rs36690 chr19:17910483 C/T cg03316864 chr19:17906309 B3GNT3 0.46 5.55 0.45 1.62e-7 Tumor biomarkers; TGCT cis rs6912958 0.514 rs7767449 chr6:87887985 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.66 -6.67 -0.51 7.5e-10 Monocyte percentage of white cells; TGCT cis rs5769765 0.862 rs9616385 chr22:50313124 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs2486012 0.737 rs37457 chr1:44291191 G/A cg12908607 chr1:44402522 ARTN -0.69 -5.35 -0.43 4.16e-7 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs72809688 chr2:26516579 G/A cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.4 -4.76 -0.39 5.24e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs10782582 0.609 rs5745469 chr1:76347394 G/A cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs4506170 1.000 rs60163266 chr8:128323157 G/A cg07795030 chr8:128802207 NA -0.21 -4.61 -0.38 9.75e-6 Prostate cancer; TGCT cis rs986417 0.748 rs12436632 chr14:61034416 T/C cg27398547 chr14:60952738 C14orf39 1.33 10.37 0.68 1.56e-18 Gut microbiota (bacterial taxa); TGCT cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.83 -8.54 -0.61 4.12e-14 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.524 rs77498725 chr17:29063986 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs425277 0.917 rs262656 chr1:2088754 A/C cg03732007 chr1:2071316 PRKCZ 0.26 5.41 0.44 3.07e-7 Height; TGCT cis rs17767294 0.708 rs113741085 chr6:27849982 C/A cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.78 0.46 5.58e-8 Schizophrenia; TGCT cis rs1799949 0.965 rs6503726 chr17:41284742 T/C cg05368731 chr17:41323189 NBR1 1.04 11.28 0.71 9.71e-21 Menopause (age at onset); TGCT cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg02458000 chr6:26745757 NA 0.51 4.77 0.39 5.08e-6 Intelligence (multi-trait analysis); TGCT cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg11941060 chr3:133502564 NA -0.26 -5.32 -0.43 4.74e-7 Iron status biomarkers; TGCT cis rs10771431 0.597 rs10843142 chr12:9357502 A/G cg08997352 chr12:9597637 DDX12 -0.25 -5.04 -0.41 1.63e-6 Breast size; TGCT cis rs6688613 0.694 rs1476347 chr1:166815587 G/T cg07049167 chr1:166818506 POGK 0.24 5.08 0.42 1.34e-6 Refractive astigmatism; TGCT cis rs9467711 0.606 rs2073531 chr6:26375256 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6430585 1.000 rs73958618 chr2:136500475 A/G cg07169764 chr2:136633963 MCM6 0.88 7.84 0.58 1.78e-12 Corneal structure; TGCT cis rs11098499 0.954 rs11734241 chr4:120416872 A/G cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg07424592 chr7:64974309 NA -0.56 -5.36 -0.43 3.83e-7 Calcium levels; TGCT cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg19774624 chr17:42201019 HDAC5 -0.87 -10.86 -0.7 1.02e-19 Total body bone mineral density; TGCT cis rs10791097 0.582 rs2282578 chr11:130735691 A/T cg12179176 chr11:130786555 SNX19 0.81 9.76 0.66 4.74e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10876993 0.890 rs12302350 chr12:58062589 T/G cg15848620 chr12:58087721 OS9 -0.71 -5.63 -0.45 1.13e-7 Celiac disease or Rheumatoid arthritis; TGCT cis rs6582630 0.519 rs4002440 chr12:38485012 A/G cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT trans rs6762477 0.748 rs3755831 chr3:50228767 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.78 -7.85 -0.58 1.68e-12 Menarche (age at onset); TGCT cis rs17443541 0.507 rs6435020 chr2:200448356 C/T cg00055341 chr2:200446845 NA -0.34 -4.63 -0.38 9.15e-6 Intelligence (multi-trait analysis); TGCT cis rs8072100 0.764 rs2644349 chr17:45641743 G/A cg08085267 chr17:45401833 C17orf57 0.42 4.62 0.38 9.57e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9611519 0.929 rs4820423 chr22:41430338 A/T cg03806693 chr22:41940476 POLR3H -0.7 -6.22 -0.49 6.88e-9 Neuroticism; TGCT cis rs17711722 0.727 rs781151 chr7:65479878 T/C cg18876405 chr7:65276391 NA 0.4 6.37 0.5 3.34e-9 Calcium levels; TGCT cis rs131805 1.000 rs3091397 chr22:50957520 C/T cg25309564 chr22:51001381 C22orf41 0.5 4.67 0.39 7.67e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs77972916 0.611 rs61552842 chr2:43584036 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.37 -5.45 -0.44 2.61e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs8141529 0.748 rs5762881 chr22:29289346 C/A cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs11651000 0.761 rs11657388 chr17:45820707 C/G cg06532163 chr17:45867833 NA 0.33 4.82 0.4 4.05e-6 IgG glycosylation; TGCT cis rs79057730 0.527 rs35316052 chr7:802954 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.76 5.84 0.46 4.31e-8 Initial pursuit acceleration; TGCT cis rs3796352 1.000 rs13074524 chr3:52974184 A/G cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7208859 0.524 rs73263982 chr17:28920624 T/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg04389838 chr3:44770851 ZNF501 -0.42 -5.69 -0.45 8.77e-8 Depressive symptoms; TGCT cis rs274567 0.602 rs272853 chr5:131688561 A/G cg16647868 chr5:131706066 SLC22A5 0.32 4.77 0.39 4.97e-6 Blood metabolite levels; TGCT cis rs1008375 0.932 rs6449317 chr4:17631253 T/C cg18681998 chr4:17616180 MED28 0.97 9.68 0.66 7.47e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs75686122 0.892 rs17807953 chr8:104638505 A/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7829975 0.902 rs485107 chr8:8581408 C/G cg08975724 chr8:8085496 FLJ10661 -0.52 -4.53 -0.38 1.39e-5 Mood instability; TGCT cis rs9467773 1.000 rs4713006 chr6:26519872 A/G cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9357506 1.000 rs6940825 chr6:46304945 C/T cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.37e-7 Body mass index; TGCT cis rs35306767 1.000 rs35306767 chr10:989437 A/T cg20503657 chr10:835505 NA 0.62 8.19 0.59 2.64e-13 Eosinophil percentage of granulocytes; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg08736216 chr1:53307985 ZYG11A -0.28 -5.58 -0.45 1.44e-7 Monocyte count; TGCT cis rs2227564 0.620 rs3812637 chr10:75568846 C/T cg04320760 chr10:75533139 FUT11 -0.32 -4.53 -0.38 1.35e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11809207 0.719 rs4659415 chr1:26580790 C/T cg03844060 chr1:26490628 NA 0.27 5.22 0.42 7.22e-7 Height; TGCT cis rs394563 0.775 rs399673 chr6:149783221 T/C cg03678062 chr6:149772716 ZC3H12D -0.36 -4.45 -0.37 1.87e-5 Dupuytren's disease; TGCT cis rs526231 0.819 rs2288788 chr5:102600569 A/C cg05225461 chr5:102596755 C5orf30 0.24 4.79 0.4 4.7e-6 Primary biliary cholangitis; TGCT cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.68 0.45 9.24e-8 Height; TGCT trans rs4332037 0.552 rs11773627 chr7:2002733 A/G cg10840412 chr1:235813424 GNG4 0.87 6.66 0.51 7.87e-10 Bipolar disorder; TGCT cis rs9915657 1.000 rs9910864 chr17:70123028 T/A cg06234051 chr17:70120541 SOX9 -0.29 -5.62 -0.45 1.17e-7 Thyroid hormone levels; TGCT cis rs4975616 0.773 rs414965 chr5:1324121 G/A cg07493874 chr5:1342172 CLPTM1L -0.28 -6.77 -0.52 4.62e-10 Lung cancer; TGCT cis rs9611565 0.649 rs9623450 chr22:42175231 G/A cg03806693 chr22:41940476 POLR3H 0.9 8.76 0.62 1.2e-14 Vitiligo; TGCT cis rs7715806 0.500 rs17649332 chr5:75003878 T/C cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7044106 0.791 rs10984997 chr9:123481206 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 7.21 0.54 4.88e-11 Hip circumference adjusted for BMI; TGCT cis rs61776719 0.875 rs10890238 chr1:38445654 A/T cg26398791 chr1:38455867 SF3A3 -0.62 -6.23 -0.49 6.65e-9 Coronary artery disease; TGCT cis rs4689388 0.727 rs1801213 chr4:6293696 C/G cg14416269 chr4:6271139 WFS1 0.46 5.77 0.46 5.93e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1218582 0.772 rs6699043 chr1:154913021 T/C cg09359103 chr1:154839909 KCNN3 -0.62 -11.25 -0.71 1.15e-20 Prostate cancer; TGCT cis rs1577917 0.874 rs1838954 chr6:86565478 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs6831352 0.918 rs29001216 chr4:100051556 A/T cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs12049351 0.774 rs12030128 chr1:229622863 A/G cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs4319547 0.695 rs4758643 chr12:122924819 A/T cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.38 -0.44 3.58e-7 Body mass index; TGCT cis rs9399135 0.933 rs28384512 chr6:135376232 C/T cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs752010 0.574 rs10890157 chr1:42117689 C/G cg06885757 chr1:42089581 HIVEP3 0.24 4.48 0.37 1.69e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs899997 1.000 rs11632672 chr15:79044330 A/G cg00061860 chr15:78953028 NA -0.27 -4.67 -0.39 7.62e-6 Coronary artery disease or large artery stroke; TGCT cis rs9549260 0.755 rs9549255 chr13:41235213 C/T cg21288729 chr13:41239152 FOXO1 1.01 10.71 0.69 2.36e-19 Red blood cell count; TGCT cis rs2580764 0.632 rs2588510 chr2:55199248 A/G cg09592903 chr2:55203963 RTN4 -0.24 -5.53 -0.44 1.84e-7 Mean platelet volume; TGCT cis rs7666738 0.830 rs10017557 chr4:98983969 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.850 rs12441127 chr15:44021175 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs9814567 1.000 rs9809619 chr3:134280948 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.34 -0.64 4.93e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2486288 0.586 rs12909883 chr15:45572054 G/C cg26924012 chr15:45694286 SPATA5L1 -0.79 -7.73 -0.57 3.24e-12 Glomerular filtration rate; TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg20064778 chr22:24384315 GSTT1 -0.49 -4.58 -0.38 1.12e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg13665807 chr20:60559372 TAF4 -0.5 -5.21 -0.42 7.51e-7 Body mass index; TGCT cis rs9443645 0.808 rs2050661 chr6:79661125 T/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs4700695 0.668 rs253214 chr5:65499401 A/G cg21114390 chr5:65439923 SFRS12 -0.81 -7.63 -0.57 5.36e-12 Facial morphology (factor 19); TGCT cis rs10791323 0.511 rs4937837 chr11:133731134 T/C cg15485101 chr11:133734466 NA 0.42 5.26 0.43 6.25e-7 Childhood ear infection; TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg11062466 chr8:58055876 NA 0.44 5.02 0.41 1.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs769267 0.965 rs2074296 chr19:19373689 A/G cg03709012 chr19:19516395 GATAD2A 0.64 5.38 0.43 3.65e-7 Tonsillectomy; TGCT cis rs17376456 1.000 rs61132622 chr5:93539684 G/A cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs7103648 0.630 rs7120548 chr11:47662932 A/G cg20307385 chr11:47447363 PSMC3 0.9 8.62 0.61 2.58e-14 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs7666738 0.830 rs11947027 chr4:99005941 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs981844 0.775 rs1037656 chr4:154750786 A/G cg14289246 chr4:154710475 SFRP2 -0.96 -8.42 -0.6 7.72e-14 Response to statins (LDL cholesterol change); TGCT cis rs9372498 0.536 rs9481808 chr6:118784571 G/A cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs3008870 1.000 rs2985822 chr1:67404910 T/G cg03991309 chr1:68237761 GNG12 0.27 4.55 0.38 1.26e-5 Lymphocyte percentage of white cells; TGCT cis rs7598759 0.548 rs1584462 chr2:232369798 A/G cg19187155 chr2:232395269 NMUR1 0.52 6.2 0.49 7.61e-9 Noise-induced hearing loss; TGCT cis rs12148488 0.816 rs4886655 chr15:75385568 C/T cg10253484 chr15:75165896 SCAMP2 -0.52 -4.5 -0.37 1.56e-5 Caffeine consumption; TGCT cis rs4654899 0.865 rs12130664 chr1:21332812 G/T cg01072550 chr1:21505969 NA -0.46 -6.77 -0.52 4.63e-10 Superior frontal gyrus grey matter volume; TGCT cis rs7614311 0.689 rs73122704 chr3:63841228 C/T cg22134162 chr3:63841271 THOC7 -0.41 -4.58 -0.38 1.1e-5 Lung function (FVC);Lung function (FEV1); TGCT cis rs2742417 0.935 rs1468543 chr3:45776900 A/G cg04837898 chr3:45731254 SACM1L -0.53 -5.52 -0.44 1.92e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs3806843 1.000 rs7732179 chr5:140199039 G/A cg19875535 chr5:140030758 IK 0.36 5.82 0.46 4.74e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9291683 0.546 rs6829727 chr4:10051672 A/C cg00071950 chr4:10020882 SLC2A9 0.56 6.29 0.49 4.98e-9 Bone mineral density; TGCT cis rs4319547 0.695 rs7301515 chr12:122949673 T/C cg05707623 chr12:122985044 ZCCHC8 -0.64 -4.94 -0.41 2.45e-6 Body mass index; TGCT cis rs739496 0.579 rs3213628 chr12:112280773 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs1011108 0.622 rs744539 chr2:26804122 T/G cg18742855 chr2:26800399 C2orf70 -0.25 -5.7 -0.46 8.12e-8 Periodontal microbiota; TGCT cis rs6964587 1.000 rs6942649 chr7:91594510 A/G cg22709100 chr7:91322751 NA 0.3 4.77 0.39 5.15e-6 Breast cancer; TGCT cis rs67072384 0.901 rs72964856 chr11:72473299 T/G cg03713592 chr11:72463424 ARAP1 -0.88 -4.49 -0.37 1.62e-5 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs4665809 0.838 rs6546749 chr2:26306288 T/C cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs473651 0.904 rs10929275 chr2:239323169 A/G cg21699342 chr2:239360505 ASB1 0.18 4.81 0.4 4.28e-6 Multiple system atrophy; TGCT cis rs9916302 0.904 rs4794814 chr17:37696852 G/A cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs116095464 0.558 rs10055354 chr5:243794 G/A cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs17268829 0.927 rs10234392 chr7:94082994 T/C cg06439941 chr7:93550756 GNG11 -0.24 -4.47 -0.37 1.74e-5 Breast cancer; TGCT cis rs2980439 0.517 rs712253 chr8:8103782 C/T cg06636001 chr8:8085503 FLJ10661 -0.61 -5.33 -0.43 4.51e-7 Neuroticism; TGCT cis rs4654899 0.865 rs10916951 chr1:21528835 A/G cg01072550 chr1:21505969 NA 0.47 7.02 0.53 1.27e-10 Superior frontal gyrus grey matter volume; TGCT cis rs10744422 0.686 rs967281 chr12:123292179 A/G cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs10791097 0.702 rs10894267 chr11:130714861 C/T cg12179176 chr11:130786555 SNX19 -0.61 -6.34 -0.49 3.95e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs1814175 0.935 rs11040438 chr11:49622521 G/A cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs2404602 0.647 rs920712 chr15:77033934 G/A cg23625390 chr15:77176239 SCAPER -0.36 -4.52 -0.38 1.42e-5 Blood metabolite levels; TGCT cis rs9486719 1.000 rs2179126 chr6:96871350 A/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs2576037 0.583 rs2571028 chr18:44561100 C/G cg23302884 chr18:44338147 ST8SIA5 0.39 4.62 0.38 9.65e-6 Personality dimensions; TGCT cis rs3760776 0.522 rs78060698 chr19:5832773 G/A cg25387410 chr19:5844109 FUT3 -0.56 -6.47 -0.5 2.08e-9 N-glycan levels;Tumor biomarkers;Vitamin B12 levels; TGCT cis rs1799949 0.965 rs2236762 chr17:41226675 A/T cg23758822 chr17:41437982 NA 0.69 6.82 0.52 3.55e-10 Menopause (age at onset); TGCT cis rs8056742 0.643 rs12932104 chr16:85090182 C/G cg00229868 chr16:85520891 NA 0.36 4.83 0.4 3.96e-6 Amyotrophic lateral sclerosis; TGCT cis rs6867032 0.687 rs4998338 chr5:2015910 A/G cg26168224 chr5:2018326 NA 0.43 7.96 0.58 9.31e-13 Gut microbiome composition (winter); TGCT cis rs6089829 0.962 rs3746749 chr20:61667333 T/C cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs11676348 0.729 rs13013361 chr2:218947515 A/T cg00012203 chr2:219082015 ARPC2 -0.48 -4.51 -0.38 1.46e-5 Ulcerative colitis; TGCT cis rs2243480 0.522 rs73150635 chr7:65972490 C/T cg07424592 chr7:64974309 NA 1.44 8.81 0.62 9.18e-15 Diabetic kidney disease; TGCT cis rs2486288 0.656 rs6493144 chr15:45573489 C/G cg26924012 chr15:45694286 SPATA5L1 0.77 8.0 0.58 7.59e-13 Glomerular filtration rate; TGCT trans rs7618501 0.966 rs7372966 chr3:49788969 T/C cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs1385374 0.858 rs10847692 chr12:129289679 A/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs4242434 0.672 rs10113779 chr8:22485934 G/C cg03733263 chr8:22462867 KIAA1967 0.98 13.14 0.76 2.97e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7772486 0.686 rs9497380 chr6:145955305 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs739496 0.579 rs57046217 chr12:112285116 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT trans rs3780486 0.505 rs1411609 chr9:33137303 C/T cg04842962 chr6:43655489 MRPS18A 0.82 8.79 0.62 1.03e-14 IgG glycosylation; TGCT cis rs116095464 0.558 rs55833259 chr5:286728 G/A cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT trans rs2727020 0.930 rs1164688 chr11:49290604 C/G cg15704280 chr7:45808275 SEPT13 0.72 7.71 0.57 3.47e-12 Coronary artery disease; TGCT cis rs9486719 1.000 rs4078038 chr6:96904366 A/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.35 -0.43 4.14e-7 Migraine;Coronary artery disease; TGCT cis rs7647973 0.961 rs11130186 chr3:49275828 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.55 -4.48 -0.37 1.68e-5 Menarche (age at onset); TGCT cis rs2050392 0.517 rs656600 chr10:30765654 G/A cg18806716 chr10:30721971 MAP3K8 -0.47 -5.42 -0.44 3.04e-7 Inflammatory bowel disease; TGCT cis rs910316 0.967 rs119076 chr14:75572419 G/T cg23033748 chr14:75592666 NEK9 -0.29 -4.83 -0.4 3.97e-6 Height; TGCT cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg03609598 chr5:56110824 MAP3K1 -0.6 -4.48 -0.37 1.69e-5 Initial pursuit acceleration; TGCT cis rs9393692 0.645 rs6939048 chr6:26327953 G/A cg13736514 chr6:26305472 NA -0.45 -6.65 -0.51 8.17e-10 Educational attainment; TGCT cis rs854765 0.647 rs6826 chr17:18011140 C/T cg04398451 chr17:18023971 MYO15A -0.38 -6.48 -0.5 1.91e-9 Total body bone mineral density; TGCT cis rs9894429 0.546 rs9906979 chr17:79608765 A/G cg18240062 chr17:79603768 NPLOC4 0.75 7.08 0.54 9.3e-11 Eye color traits; TGCT cis rs854765 0.693 rs12936037 chr17:17777245 A/G cg09796270 chr17:17721594 SREBF1 -0.27 -5.52 -0.44 1.94e-7 Total body bone mineral density; TGCT cis rs1903068 0.819 rs17711320 chr4:56000053 A/C cg09978860 chr4:56023921 NA 0.57 6.47 0.5 2.1e-9 Endometriosis; TGCT cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg17747265 chr1:1875780 NA -0.42 -7.92 -0.58 1.16e-12 Body mass index; TGCT cis rs10149470 0.549 rs9652403 chr14:104036024 G/C cg26031613 chr14:104095156 KLC1 0.56 4.99 0.41 2.02e-6 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); TGCT cis rs12477438 0.953 rs3851334 chr2:99794704 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.77 -5.89 -0.47 3.32e-8 Chronic sinus infection; TGCT cis rs782590 0.902 rs782595 chr2:55845596 C/G cg18811423 chr2:55921094 PNPT1 0.64 6.52 0.51 1.6e-9 Metabolic syndrome; TGCT cis rs9486719 0.843 rs2472875 chr6:96844691 G/A cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs7017914 0.934 rs62530826 chr8:71641643 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs6582630 0.555 rs34145279 chr12:38405588 T/C cg13010199 chr12:38710504 ALG10B 0.61 4.82 0.4 4.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs514406 0.861 rs4926576 chr1:53226775 C/T cg01802117 chr1:53393560 SCP2 0.43 5.13 0.42 1.1e-6 Monocyte count; TGCT cis rs12049351 0.665 rs1838464 chr1:229616693 T/C cg12130225 chr1:229698885 NA 0.39 4.5 0.37 1.55e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs28595532 0.920 rs17323877 chr4:119671188 A/G cg14228332 chr4:119757509 SEC24D 1.06 5.67 0.45 9.69e-8 Cannabis dependence symptom count; TGCT cis rs7937682 0.889 rs7948236 chr11:111499933 C/A cg09085632 chr11:111637200 PPP2R1B -1.09 -11.56 -0.72 2.06e-21 Primary sclerosing cholangitis; TGCT cis rs9467711 0.606 rs72836482 chr6:26359241 A/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12620999 0.838 rs7589198 chr2:237967615 C/T cg23555395 chr2:238036564 NA 0.27 4.81 0.4 4.35e-6 Systemic lupus erythematosus; TGCT cis rs4819052 0.808 rs2246697 chr21:46689999 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs798766 1.000 rs2166580 chr4:1743169 G/A cg05874882 chr4:1763078 NA -0.36 -4.83 -0.4 3.87e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs6138458 1.000 rs6114984 chr20:24976610 A/G cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT trans rs2688608 0.839 rs2675662 chr10:75599127 A/G cg13918328 chr10:52500089 ASAH2B -0.69 -6.72 -0.52 5.91e-10 Inflammatory bowel disease; TGCT cis rs4819052 0.851 rs7276828 chr21:46695039 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs35849525 0.776 rs7615318 chr3:49987475 C/T cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs9486719 1.000 rs34236778 chr6:96884556 C/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs13336428 0.730 rs28653458 chr16:1525850 T/C cg08008072 chr16:1524255 CLCN7 -0.61 -9.03 -0.63 2.77e-15 Bone mineral density; TGCT cis rs2012796 0.743 rs61986598 chr14:81856865 G/A cg02996355 chr14:81879375 NA 0.56 5.45 0.44 2.66e-7 Night sleep phenotypes; TGCT cis rs4819052 1.000 rs2838830 chr21:46664227 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.77 6.05 0.48 1.56e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6570726 0.935 rs424263 chr6:145840073 A/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.560 rs1889033 chr1:53211887 A/G cg08859206 chr1:53392774 SCP2 0.36 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs7043114 0.525 rs6479417 chr9:95064562 G/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.57 -0.45 1.53e-7 Height; TGCT cis rs916888 0.821 rs415430 chr17:44859144 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9611565 0.694 rs5758324 chr22:41787950 G/T cg06634786 chr22:41940651 POLR3H -0.8 -7.61 -0.56 6.1e-12 Vitiligo; TGCT cis rs9527 0.615 rs17725614 chr10:104685493 G/C cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs9486715 0.867 rs9373829 chr6:96897201 A/C cg18709589 chr6:96969512 KIAA0776 -0.69 -6.69 -0.51 7.02e-10 Headache; TGCT cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs344364 0.511 rs12596510 chr16:1949480 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT trans rs1814175 0.645 rs4598671 chr11:50003191 C/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs459571 0.839 rs2519831 chr9:136886257 T/A cg14405625 chr9:136855902 VAV2 -0.3 -4.5 -0.37 1.52e-5 Platelet distribution width; TGCT cis rs228437 0.657 rs6902569 chr6:134947804 G/C cg09872934 chr6:134495829 SGK1 -0.57 -4.54 -0.38 1.33e-5 Melanoma; TGCT cis rs2637266 0.739 rs2583041 chr10:78439219 C/T cg18941641 chr10:78392320 NA -0.41 -4.91 -0.4 2.86e-6 Pulmonary function; TGCT cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 6.24 0.49 6.24e-9 Menarche (age at onset); TGCT cis rs2361718 0.631 rs12601637 chr17:78142455 T/C cg21238619 chr17:78079768 GAA -0.31 -4.57 -0.38 1.16e-5 Yeast infection; TGCT cis rs9549367 0.713 rs4907598 chr13:113861385 C/T cg18105134 chr13:113819100 PROZ 0.47 8.38 0.6 9.82e-14 Platelet distribution width; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg22166914 chr1:53195759 ZYG11B 0.29 4.89 0.4 3.09e-6 Monocyte count; TGCT cis rs514406 0.825 rs28817407 chr1:53226116 G/A cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.29e-11 Monocyte count; TGCT cis rs7714584 1.000 rs3857422 chr5:150268609 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg03806693 chr22:41940476 POLR3H -1.12 -12.12 -0.74 8.54e-23 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs13112131 chr4:98976784 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs924607 1.000 rs924607 chr5:610093 C/T cg18765565 chr5:669397 TPPP -0.62 -6.97 -0.53 1.66e-10 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.88 9.32 0.64 5.46e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs7192750 0.539 rs12926300 chr16:71978997 C/T cg06353428 chr16:71660113 MARVELD3 0.77 6.82 0.52 3.61e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs6684514 1.000 rs3806408 chr1:156252137 C/A cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2439831 0.867 rs496584 chr15:43831923 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.94 7.22 0.54 4.65e-11 Lung cancer in ever smokers; TGCT cis rs875971 1.000 rs10244498 chr7:66116056 A/G cg18876405 chr7:65276391 NA 0.33 4.96 0.41 2.24e-6 Aortic root size; TGCT cis rs13102973 0.617 rs11734991 chr4:135885411 T/G cg14419869 chr4:135874104 NA 0.26 4.55 0.38 1.28e-5 Subjective well-being; TGCT cis rs514406 0.861 rs7526275 chr1:53245849 C/T cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.47 0.5 2.08e-9 Cognitive function; TGCT cis rs7267979 1.000 rs4813562 chr20:25352588 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11971779 0.688 rs1862880 chr7:139020100 T/C cg07862535 chr7:139043722 LUC7L2 0.71 5.69 0.46 8.6e-8 Diisocyanate-induced asthma; TGCT cis rs9814567 0.896 rs7653880 chr3:134345788 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.8 -7.29 -0.55 3.14e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2404602 0.716 rs8030411 chr15:76699855 A/G cg22467129 chr15:76604101 ETFA -0.59 -7.38 -0.55 2.02e-11 Blood metabolite levels; TGCT cis rs6582630 0.584 rs12832156 chr12:38419435 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs651907 0.535 rs13084113 chr3:101534039 C/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.87 0.4 3.32e-6 Colorectal cancer; TGCT cis rs7945705 0.935 rs11042102 chr11:8882164 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.94 0.41 2.5e-6 Hemoglobin concentration; TGCT cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg12310025 chr6:25882481 NA -0.54 -5.7 -0.46 8.31e-8 Height; TGCT cis rs2688608 0.933 rs2688614 chr10:75652876 G/A cg04320760 chr10:75533139 FUT11 -0.29 -4.55 -0.38 1.27e-5 Inflammatory bowel disease; TGCT cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg19774624 chr17:42201019 HDAC5 -0.87 -10.86 -0.7 1.02e-19 Total body bone mineral density; TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs7474896 0.583 rs10827818 chr10:38000856 T/C cg25427524 chr10:38739819 LOC399744 -0.34 -5.47 -0.44 2.43e-7 Obesity (extreme); TGCT cis rs826838 1.000 rs1963562 chr12:38662896 C/T cg13010199 chr12:38710504 ALG10B 0.77 6.31 0.49 4.59e-9 Heart rate; TGCT cis rs79057730 0.528 rs4719313 chr7:822501 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.65 6.04 0.48 1.67e-8 Initial pursuit acceleration; TGCT cis rs10540 1.000 rs12786555 chr11:506229 C/T cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs6087990 0.735 rs1040555 chr20:31380201 A/T cg13636640 chr20:31349939 DNMT3B -0.97 -13.01 -0.76 6.33e-25 Ulcerative colitis; TGCT cis rs939574 0.512 rs55908154 chr2:220145960 G/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.78 5.54 0.45 1.71e-7 Platelet distribution width; TGCT cis rs8070740 0.786 rs34856659 chr17:5327572 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.55 0.38 1.27e-5 Menopause (age at onset); TGCT cis rs10461617 0.541 rs832575 chr5:56161787 C/T cg20203395 chr5:56204925 C5orf35 -0.67 -4.62 -0.38 9.56e-6 Type 2 diabetes; TGCT cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg24675658 chr1:53192096 ZYG11B 0.87 11.29 0.71 9.39e-21 Monocyte count; TGCT cis rs4417704 0.551 rs10169006 chr2:241898824 A/G cg04034577 chr2:241836375 C2orf54 -0.31 -4.45 -0.37 1.86e-5 Joint mobility (Beighton score); TGCT cis rs1062177 1.000 rs2016409 chr5:151126324 G/T cg12924095 chr5:151150029 G3BP1 -0.35 -5.04 -0.41 1.6e-6 Preschool internalizing problems; TGCT cis rs17513268 0.808 rs112823227 chr17:59333956 C/T cg12597983 chr17:59531696 NA -0.4 -4.52 -0.38 1.45e-5 Obesity-related traits; TGCT cis rs854765 0.663 rs16960744 chr17:17755259 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.26 -0.55 3.78e-11 Total body bone mineral density; TGCT cis rs4780401 0.546 rs3743588 chr16:11836508 G/A cg01061890 chr16:11836724 TXNDC11 0.6 4.95 0.41 2.36e-6 Rheumatoid arthritis; TGCT cis rs7617773 0.780 rs34749846 chr3:48347168 T/G cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs769267 0.792 rs4808961 chr19:19577215 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.72 6.06 0.48 1.53e-8 Tonsillectomy; TGCT cis rs2235642 0.821 rs2281236 chr16:1603576 G/A cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.64 -0.45 1.08e-7 Coronary artery disease; TGCT cis rs782590 0.683 rs782633 chr2:55898203 A/G cg18811423 chr2:55921094 PNPT1 0.65 6.76 0.52 4.79e-10 Metabolic syndrome; TGCT cis rs7216064 1.000 rs7208663 chr17:65885171 T/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.07e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1371867 0.846 rs1788189 chr8:101249762 G/T cg00191853 chr8:101177733 SPAG1 0.23 4.67 0.39 7.55e-6 Atrioventricular conduction; TGCT cis rs950027 0.620 rs2467862 chr15:45643843 T/G cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs758129 0.501 rs2856268 chr15:89878391 T/C cg24365117 chr15:89879190 POLG 0.34 4.63 0.38 9.16e-6 Schizophrenia; TGCT cis rs667920 0.512 rs13071085 chr3:136014923 G/A cg15507776 chr3:136538369 TMEM22 -0.62 -4.6 -0.38 1.01e-5 Coronary artery disease; TGCT cis rs317689 0.581 rs315132 chr12:69761996 G/C cg14784868 chr12:69753453 YEATS4 0.64 5.72 0.46 7.3900000000000007e-08 Response to diuretic therapy; TGCT cis rs7674212 0.541 rs2623064 chr4:104030792 C/A cg16532752 chr4:104119610 CENPE -0.62 -5.36 -0.43 3.83e-7 Type 2 diabetes; TGCT cis rs2730260 0.537 rs73169234 chr7:158882366 C/T cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs981844 1.000 rs62325093 chr4:154669733 G/A cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT trans rs1814175 0.645 rs28478790 chr11:50054322 C/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs6987853 0.966 rs2974342 chr8:42436651 A/C cg20539142 chr8:42623718 CHRNA6 -0.2 -4.84 -0.4 3.76e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs7647973 0.626 rs7637711 chr3:49829653 A/G cg05785598 chr3:49045655 WDR6 -0.42 -5.24 -0.43 6.67e-7 Menarche (age at onset); TGCT cis rs11578119 0.933 rs1928716 chr1:170482301 T/C cg09767346 chr1:170501363 GORAB -0.67 -5.36 -0.43 3.85e-7 Male-pattern baldness; TGCT cis rs9926296 0.546 rs9935541 chr16:89905925 G/C cg21285383 chr16:89894308 SPIRE2 0.34 4.73 0.39 6.11e-6 Vitiligo; TGCT cis rs8062405 0.792 rs12446550 chr16:28543381 G/A cg09754948 chr16:28834200 ATXN2L 0.59 4.59 0.38 1.05e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg22963979 chr7:1858916 MAD1L1 -0.45 -7.41 -0.55 1.74e-11 Bipolar disorder and schizophrenia; TGCT cis rs2290402 0.536 rs60492656 chr4:875008 C/T cg23332689 chr4:987652 IDUA;SLC26A1 0.29 4.52 0.38 1.41e-5 Type 2 diabetes; TGCT cis rs68170813 0.559 rs4730239 chr7:107056960 A/T cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs6663390 0.831 rs2267894 chr1:208085735 G/A cg03990033 chr1:208084030 CD34 0.54 5.61 0.45 1.26e-7 Facial morphology (factor 18); TGCT cis rs7666738 0.830 rs13149404 chr4:99070236 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg06634786 chr22:41940651 POLR3H 0.86 8.27 0.6 1.76e-13 Vitiligo; TGCT cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg11301795 chr4:187892539 NA -0.35 -5.28 -0.43 5.6e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 0.656 rs4522419 chr16:89853307 T/C cg21285383 chr16:89894308 SPIRE2 0.33 4.57 0.38 1.14e-5 Vitiligo; TGCT cis rs4595586 1.000 rs1523118 chr12:39229699 C/T cg10518543 chr12:38710700 ALG10B -0.51 -5.09 -0.42 1.32e-6 Morning vs. evening chronotype; TGCT cis rs71435601 0.628 rs1652418 chr2:21388456 T/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs11671005 0.735 rs11668814 chr19:58946833 T/C cg13877915 chr19:58951672 ZNF132 0.63 5.0 0.41 1.95e-6 Mean platelet volume; TGCT cis rs6785206 0.554 rs12054283 chr3:128505829 A/G cg25356066 chr3:128598488 ACAD9 -0.78 -4.45 -0.37 1.91e-5 Lymphocyte percentage of white cells; TGCT cis rs6121246 0.542 rs2376990 chr20:30238744 G/A cg18721089 chr20:30220636 NA -0.5 -5.05 -0.41 1.57e-6 Mean corpuscular hemoglobin; TGCT cis rs5769765 1.000 rs768618 chr22:50286827 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs9291683 0.632 rs13101785 chr4:10042915 T/A cg00071950 chr4:10020882 SLC2A9 0.68 8.74 0.62 1.38e-14 Bone mineral density; TGCT cis rs2180341 0.961 rs9375501 chr6:127652539 C/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs7412746 0.658 rs4970987 chr1:150949682 T/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.7 0.39 6.78e-6 Melanoma; TGCT cis rs9796 0.558 rs11855102 chr15:41513257 T/C cg18705301 chr15:41695430 NDUFAF1 -0.53 -7.11 -0.54 8.15e-11 Menopause (age at onset); TGCT cis rs11209185 0.545 rs1926284 chr1:68446291 T/C cg22082780 chr1:68452167 NA 0.32 4.81 0.4 4.35e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs508618 0.731 rs576462 chr1:231544607 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.6 -4.92 -0.4 2.64e-6 Red blood cell count; TGCT cis rs7249142 0.549 rs2239369 chr19:19292405 A/T cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B -0.54 -5.44 -0.44 2.73e-7 IgG glycosylation; TGCT cis rs17376456 0.569 rs10057664 chr5:93182274 C/T cg25358565 chr5:93447407 FAM172A -0.81 -6.54 -0.51 1.47e-9 Diabetic retinopathy; TGCT cis rs9532580 0.619 rs2755211 chr13:41142223 C/T cg21288729 chr13:41239152 FOXO1 0.89 7.47 0.56 1.24e-11 Mean corpuscular hemoglobin; TGCT cis rs4409675 0.576 rs2295367 chr1:28224312 C/T cg23691781 chr1:28212827 C1orf38 0.25 5.26 0.43 6.19e-7 Corneal astigmatism; TGCT cis rs4851254 0.579 rs78633727 chr2:100669457 T/C cg07810366 chr2:100720526 AFF3 -0.49 -5.04 -0.41 1.61e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT trans rs208520 0.690 rs12213575 chr6:66735989 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs9534288 0.797 rs9526132 chr13:46609364 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs7216064 1.000 rs58551145 chr17:65837235 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs988712 0.622 rs2030323 chr11:27728539 A/C cg10635145 chr11:27742435 BDNF 0.44 6.37 0.5 3.35e-9 Obesity; TGCT cis rs6695640 0.854 rs942458 chr1:17739313 A/C cg25979543 chr1:17888104 ARHGEF10L -0.26 -4.62 -0.38 9.41e-6 Mean platelet volume; TGCT cis rs7824557 0.602 rs7817658 chr8:11206543 A/G cg21775007 chr8:11205619 TDH 0.73 7.01 0.53 1.32e-10 Retinal vascular caliber; TGCT cis rs7267979 0.966 rs2257461 chr20:25265554 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs763121 0.853 rs5757253 chr22:39104320 C/T cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT cis rs13064411 0.696 rs6786974 chr3:113190149 T/A cg18753928 chr3:113234510 CCDC52 -0.71 -5.59 -0.45 1.35e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs1799949 1.000 rs8070085 chr17:41341984 C/T cg23758822 chr17:41437982 NA -0.59 -5.89 -0.47 3.41e-8 Menopause (age at onset); TGCT cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg26116260 chr4:7069785 GRPEL1 1.12 11.07 0.7 3.2e-20 Monocyte percentage of white cells; TGCT cis rs427394 0.659 rs274695 chr5:6732252 G/C cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs9906944 0.678 rs56015440 chr17:47136631 C/G cg20966754 chr17:47091339 IGF2BP1 -0.46 -5.12 -0.42 1.12e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs4654899 0.865 rs6658526 chr1:21391314 A/G cg01072550 chr1:21505969 NA 0.44 6.12 0.48 1.12e-8 Superior frontal gyrus grey matter volume; TGCT cis rs28493229 0.522 rs17713068 chr19:41270055 A/C cg00475131 chr19:41117096 LTBP4 0.29 4.49 0.37 1.61e-5 Kawasaki disease; TGCT cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg06634786 chr22:41940651 POLR3H -0.88 -8.27 -0.6 1.75e-13 Vitiligo; TGCT cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg08048268 chr3:133502702 NA -0.56 -7.47 -0.56 1.27e-11 Iron status biomarkers; TGCT trans rs17471911 0.708 rs9633709 chr10:100807955 C/T cg03484267 chr2:207988651 KLF7 -0.52 -6.67 -0.51 7.53e-10 Neuroticism; TGCT cis rs9916302 0.904 rs650106 chr17:37451559 A/G cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs694739 0.628 rs617051 chr11:64133638 C/A cg02228329 chr11:64053129 BAD;GPR137 0.69 6.71 0.52 6.1e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9393777 0.513 rs13210025 chr6:26654817 A/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs6088580 0.634 rs4911422 chr20:32999345 T/C cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs9430161 0.579 rs7542164 chr1:11040223 G/A cg27631724 chr1:11040367 C1orf127 0.55 6.58 0.51 1.2e-9 Ewing sarcoma; TGCT cis rs10927875 0.691 rs1048302 chr1:16340879 T/G cg14742211 chr1:16348397 CLCNKA 0.19 4.48 0.37 1.7e-5 Dilated cardiomyopathy; TGCT cis rs7659604 0.537 rs6823818 chr4:122731699 G/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.31 -0.43 4.82e-7 Type 2 diabetes; TGCT cis rs601339 1.000 rs35683065 chr12:123164062 G/C cg11919336 chr12:123188078 GPR109A 0.64 7.49 0.56 1.1e-11 Adiponectin levels; TGCT cis rs4455778 0.557 rs4289754 chr7:49116730 C/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs9634489 0.502 rs7336870 chr13:97084677 G/A cg11411106 chr13:97107445 HS6ST3 -0.27 -5.05 -0.41 1.56e-6 Body mass index; TGCT cis rs10992471 0.756 rs10992319 chr9:95127895 G/A cg14631576 chr9:95140430 CENPP -0.29 -4.82 -0.4 4.17e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs476633 0.708 rs28547298 chr15:41446951 C/T cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.77 -0.62 1.18e-14 Glomerular filtration rate (creatinine); TGCT cis rs6570726 0.764 rs9403726 chr6:145901686 G/T cg23711669 chr6:146136114 FBXO30 0.85 9.24 0.64 8.9e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs6115153 chr20:25325567 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs889312 0.500 rs252920 chr5:56148741 C/A cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs28595532 0.920 rs115690307 chr4:119768289 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs1799949 0.965 rs8176130 chr17:41258043 C/T cg05368731 chr17:41323189 NBR1 1.2 14.59 0.79 1.08e-28 Menopause (age at onset); TGCT cis rs2777491 0.522 rs7169278 chr15:41696932 A/G cg18705301 chr15:41695430 NDUFAF1 -0.49 -6.8 -0.52 3.93e-10 Ulcerative colitis; TGCT cis rs4253772 0.513 rs6008612 chr22:46707907 G/A cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 5.14 0.42 1.02e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs9811920 0.898 rs7636776 chr3:99840446 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.41 -4.55 -0.38 1.27e-5 Axial length; TGCT cis rs12286929 0.687 rs6589487 chr11:115089927 T/C cg04580443 chr11:115547056 NA 0.24 4.51 0.38 1.47e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg25767906 chr1:53392781 SCP2 0.47 5.26 0.43 6.03e-7 Monocyte count; TGCT cis rs4653767 0.573 rs708772 chr1:226912891 A/G cg10327440 chr1:227177885 CDC42BPA -0.43 -4.85 -0.4 3.59e-6 Parkinson's disease; TGCT cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg02353165 chr6:42928485 GNMT 0.97 9.95 0.67 1.66e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7072216 0.690 rs113195335 chr10:100175532 A/C cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs597480 0.853 rs580459 chr11:85436500 T/C cg11817631 chr11:85522609 SYTL2 -0.47 -4.66 -0.39 8.18e-6 Drug-induced liver injury (nonsteroidal anti-inflammatory drugs); TGCT cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg00484396 chr16:3507460 NAT15 0.44 6.53 0.51 1.51e-9 Tuberculosis; TGCT cis rs1129187 0.702 rs2395943 chr6:42940673 A/G cg17345569 chr6:42928274 GNMT -0.49 -5.05 -0.41 1.55e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2836974 0.932 rs35571600 chr21:40590624 A/C cg11644478 chr21:40555479 PSMG1 1.0 10.6 0.69 4.32e-19 Cognitive function; TGCT trans rs9859260 0.710 rs419068 chr3:195782176 C/T cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs7568458 0.837 rs35565292 chr2:85790316 T/A cg02493740 chr2:85810744 VAMP5 -0.27 -4.89 -0.4 3.04e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs11719291 0.833 rs11713694 chr3:48833615 G/T cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 Cognitive function; TGCT cis rs7226408 0.802 rs117913067 chr18:34454822 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs11098499 0.821 rs3775852 chr4:120454556 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg24549020 chr5:56110836 MAP3K1 0.66 5.79 0.46 5.56e-8 Initial pursuit acceleration; TGCT cis rs4665630 0.803 rs1007195 chr2:23889614 A/G cg08063864 chr2:24346004 PFN4;LOC375190 -0.88 -4.55 -0.38 1.25e-5 Hypertension; TGCT cis rs6866344 0.697 rs56159071 chr5:178127246 T/A cg10224037 chr5:178157518 ZNF354A 0.94 7.97 0.58 8.92e-13 Neutrophil percentage of white cells; TGCT cis rs7568458 0.811 rs10175792 chr2:85761654 A/G cg17127132 chr2:85788382 GGCX 0.62 5.92 0.47 2.97e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2692947 0.800 rs2692936 chr2:96745729 G/A cg23100626 chr2:96804247 ASTL 0.4 4.75 0.39 5.55e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.14 0.42 1.06e-6 Platelet count; TGCT cis rs2188554 0.785 rs213952 chr7:117203417 A/G cg08576598 chr7:116962626 WNT2 -0.35 -4.52 -0.38 1.43e-5 Esophageal adenocarcinoma; TGCT cis rs601339 1.000 rs645491 chr12:123181661 T/C cg11919336 chr12:123188078 GPR109A 0.64 7.74 0.57 3.07e-12 Adiponectin levels; TGCT cis rs7666738 0.830 rs9307218 chr4:99024885 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.13 0.42 1.1e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2013441 0.932 rs3850782 chr17:20181940 A/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs6448317 1.000 rs7698504 chr4:24939386 A/T cg21108841 chr4:24914750 CCDC149 -0.65 -4.94 -0.41 2.51e-6 Heschl's gyrus morphology; TGCT cis rs11167764 0.945 rs4912619 chr5:141471847 G/A cg08523384 chr5:141488047 NDFIP1 -0.25 -4.96 -0.41 2.24e-6 Crohn's disease; TGCT cis rs9393777 0.778 rs35741362 chr6:27007687 T/C cg16898833 chr6:26189333 HIST1H4D 1.0 5.82 0.46 4.65e-8 Intelligence (multi-trait analysis); TGCT cis rs12681288 0.862 rs7814070 chr8:1020991 A/G cg04851639 chr8:1020857 NA -0.37 -6.84 -0.52 3.27e-10 Schizophrenia; TGCT cis rs9811920 0.625 rs9847283 chr3:99910320 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.4 4.7 0.39 6.7e-6 Axial length; TGCT cis rs682748 1.000 rs297180 chr5:17157291 A/C cg23987134 chr5:17158319 LOC285696 0.23 5.51 0.44 2e-7 Hippocampal atrophy; TGCT cis rs17030434 1.000 rs78249279 chr4:154718783 C/T cg14289246 chr4:154710475 SFRP2 -0.92 -7.14 -0.54 6.89e-11 Electrocardiographic conduction measures; TGCT cis rs548181 0.536 rs503288 chr11:125461787 C/T cg03464685 chr11:125439445 EI24 -1.18 -9.15 -0.63 1.43e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs910316 1.000 rs10142865 chr14:75555624 G/A cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs7833790 0.963 rs10958046 chr8:82729210 A/G cg17211192 chr8:82754475 SNX16 -1.06 -8.51 -0.61 4.89e-14 Diastolic blood pressure; TGCT cis rs9311474 1.000 rs7614727 chr3:52295895 C/T cg07507251 chr3:52567010 NT5DC2 0.43 5.84 0.46 4.21e-8 Electroencephalogram traits; TGCT cis rs185694 1.000 rs200505 chr13:30900868 G/T cg07600127 chr13:30881527 KATNAL1 -0.81 -6.53 -0.51 1.53e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg19318889 chr4:1322082 MAEA 0.27 6.55 0.51 1.38e-9 Longevity; TGCT cis rs9486715 0.825 rs211158 chr6:97022938 C/G cg06623918 chr6:96969491 KIAA0776 -1.08 -13.6 -0.77 2.39e-26 Headache; TGCT cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs6545883 0.860 rs13023037 chr2:61620989 C/T cg15711740 chr2:61764176 XPO1 0.56 5.04 0.41 1.59e-6 Tuberculosis; TGCT cis rs1205863 1.000 rs1205863 chr6:11943526 T/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs9486719 1.000 rs12213426 chr6:96896035 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs2153535 0.580 rs7769020 chr6:8457724 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs3820068 0.608 rs2057304 chr1:16017710 A/G cg05660106 chr1:15850417 CASP9 0.64 5.96 0.47 2.41e-8 Systolic blood pressure; TGCT cis rs28595532 0.920 rs116668854 chr4:119707642 A/G cg21605333 chr4:119757512 SEC24D 1.37 6.56 0.51 1.3e-9 Cannabis dependence symptom count; TGCT cis rs9914544 0.545 rs8071458 chr17:18790840 C/A cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs60843830 0.661 rs62116681 chr2:104197 A/T cg00108164 chr2:264199 ACP1;SH3YL1 0.54 4.51 0.38 1.45e-5 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10501293 0.746 rs7944338 chr11:43015799 A/G cg03447554 chr11:43094025 NA 0.44 6.32 0.49 4.2e-9 Cognitive performance; TGCT cis rs6484504 0.532 rs2774403 chr11:31320530 A/T cg14844989 chr11:31128820 NA 0.22 4.51 0.38 1.49e-5 Red blood cell count; TGCT cis rs4629710 0.592 rs13205441 chr6:131575069 G/A cg12606694 chr6:131520996 AKAP7 0.41 4.86 0.4 3.55e-6 Multiple myeloma (IgH translocation); TGCT cis rs4808199 0.948 rs2301668 chr19:19452249 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.63 4.56 0.38 1.23e-5 Nonalcoholic fatty liver disease; TGCT cis rs2404602 0.669 rs1875884 chr15:76638161 C/T cg26408565 chr15:76604113 ETFA -0.41 -5.3 -0.43 5.1e-7 Blood metabolite levels; TGCT cis rs6674176 0.561 rs4660263 chr1:44421433 A/C cg13606994 chr1:44402422 ARTN -0.46 -4.98 -0.41 2.12e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1568079 0.516 rs1571424 chr10:125220311 G/A cg02936953 chr10:124639892 FAM24B;LOC399815 -0.35 -5.29 -0.43 5.31e-7 Body mass index; TGCT cis rs11098499 0.863 rs7678400 chr4:120461957 G/A cg09307838 chr4:120376055 NA 0.7 6.6 0.51 1.06e-9 Corneal astigmatism; TGCT cis rs7819412 0.745 rs2898260 chr8:10939490 G/T cg27411982 chr8:10470053 RP1L1 -0.22 -4.87 -0.4 3.39e-6 Triglycerides; TGCT cis rs7172809 0.573 rs75657134 chr15:77532885 C/G cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT cis rs72843506 0.722 rs78041331 chr17:20208846 G/T cg18979559 chr17:20280153 CCDC144C -0.64 -4.8 -0.4 4.49e-6 Schizophrenia; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.11e-7 Lymphocyte counts; TGCT cis rs7666738 0.962 rs11932892 chr4:99072967 C/T cg05340658 chr4:99064831 C4orf37 0.52 4.85 0.4 3.68e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs56036086 0.877 rs73187247 chr22:50629872 C/T cg01548456 chr22:50352384 NA 0.37 4.82 0.4 4.15e-6 Platelet count;Plateletcrit; TGCT cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.77 -6.99 -0.53 1.54e-10 Prudent dietary pattern; TGCT trans rs7615952 0.800 rs11914298 chr3:125643772 G/A cg07211511 chr3:129823064 LOC729375 -0.48 -8.05 -0.59 5.62e-13 Blood pressure (smoking interaction); TGCT cis rs7714584 1.000 rs12659118 chr5:150324622 T/C cg22134413 chr5:150180641 NA 0.9 5.5 0.44 2.05e-7 Crohn's disease; TGCT cis rs2153535 0.580 rs6597322 chr6:8449952 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT trans rs1864729 1.000 rs2583504 chr8:98283404 G/C cg08679828 chr8:102218111 ZNF706 -1.08 -7.52 -0.56 9.47e-12 Estradiol plasma levels (breast cancer); TGCT cis rs2562456 0.793 rs2650819 chr19:21638873 C/T cg01304269 chr19:21688519 ZNF429 -0.6 -4.89 -0.4 3.07e-6 Pain; TGCT cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg09222892 chr1:25734099 RHCE -0.42 -7.15 -0.54 6.72e-11 Erythrocyte sedimentation rate; TGCT cis rs9787249 0.957 rs7518431 chr1:40214944 C/T cg24920358 chr1:40204285 PPIE -0.54 -10.0 -0.67 1.24e-17 Blood protein levels; TGCT cis rs10832169 0.967 rs2403709 chr11:14072538 C/T cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs986417 0.818 rs7156317 chr14:61087740 G/A cg27398547 chr14:60952738 C14orf39 1.45 9.82 0.66 3.5e-17 Gut microbiota (bacterial taxa); TGCT cis rs4713118 0.955 rs9468201 chr6:27687035 C/T cg10876282 chr6:28092338 ZSCAN16 0.5 4.68 0.39 7.42e-6 Parkinson's disease; TGCT cis rs2115630 0.645 rs4842978 chr15:85197253 T/C cg12863693 chr15:85201151 NMB -0.4 -5.31 -0.43 4.92e-7 P wave terminal force; TGCT cis rs17376456 0.825 rs10079708 chr5:93261796 G/C cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs11578119 0.933 rs1888173 chr1:170530657 A/G cg09767346 chr1:170501363 GORAB 0.58 4.56 0.38 1.19e-5 Male-pattern baldness; TGCT trans rs7824557 0.564 rs2572394 chr8:11235393 A/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.48e-10 Retinal vascular caliber; TGCT cis rs7618915 0.547 rs11719685 chr3:52676065 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.51 -0.61 4.8e-14 Bipolar disorder; TGCT cis rs2982552 0.775 rs2982562 chr6:152052601 C/T cg22157087 chr6:152012887 ESR1 0.21 5.19 0.42 8.32e-7 Bone properties (heel); TGCT cis rs2033711 0.840 rs10423138 chr19:58928302 T/C cg04608855 chr19:58913158 NA 0.58 5.76 0.46 6.36e-8 Uric acid clearance; TGCT cis rs7582180 0.591 rs11674569 chr2:101010860 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.69 0.39 6.95e-6 Intelligence (multi-trait analysis); TGCT cis rs3008870 1.000 rs2985818 chr1:67398916 G/A cg11518657 chr1:67396239 MIER1 0.54 4.68 0.39 7.24e-6 Lymphocyte percentage of white cells; TGCT cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg11941060 chr3:133502564 NA -0.26 -5.43 -0.44 2.88e-7 Iron status biomarkers; TGCT cis rs7714584 1.000 rs7736873 chr5:150258482 T/C cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs6750047 0.771 rs1056836 chr2:38298203 C/G cg07380506 chr2:38303506 CYP1B1 -0.71 -6.51 -0.5 1.71e-9 Cutaneous malignant melanoma;Melanoma; TGCT cis rs319204 1.000 rs2082405 chr5:146258596 C/T cg13983063 chr5:146258615 PPP2R2B 0.32 4.55 0.38 1.25e-5 Schizophrenia; TGCT cis rs858239 0.665 rs858306 chr7:23242754 A/T cg05407003 chr7:23246146 NA -0.29 -4.59 -0.38 1.05e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs9467773 1.000 rs9467796 chr6:26568411 A/G cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs9527 0.545 rs10883847 chr10:104958284 C/T cg15744005 chr10:104629667 AS3MT -0.41 -4.78 -0.39 4.88e-6 Arsenic metabolism; TGCT cis rs7772486 0.754 rs4896838 chr6:146015451 T/C cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7172809 0.573 rs60863150 chr15:77515940 C/A cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT trans rs1496653 0.602 rs35121170 chr3:23516614 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs10504229 0.639 rs56066782 chr8:58105857 A/G cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.875 rs2814875 chr6:146305810 G/A cg05347473 chr6:146136440 FBXO30 0.55 5.11 0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7017914 0.905 rs2732103 chr8:71923496 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.2e-6 Bone mineral density; TGCT cis rs12478296 0.818 rs57194240 chr2:243011545 A/G cg06360820 chr2:242988706 NA -0.62 -5.23 -0.43 6.93e-7 Obesity-related traits; TGCT cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg16145915 chr7:1198662 ZFAND2A -0.51 -6.37 -0.5 3.42e-9 Longevity;Endometriosis; TGCT trans rs7726839 0.507 rs111707179 chr5:593308 T/A cg25482853 chr8:67687455 SGK3 1.26 10.61 0.69 4.22e-19 Obesity-related traits; TGCT cis rs17473412 0.765 rs10044880 chr5:122663671 G/A cg15125798 chr5:122621645 NA -0.6 -5.34 -0.43 4.24e-7 Total body bone mineral density; TGCT cis rs769267 0.965 rs2315025 chr19:19426609 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs2742417 0.603 rs2742395 chr3:45758595 A/G cg04837898 chr3:45731254 SACM1L -0.65 -7.06 -0.54 1.03e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs79387448 0.655 rs79144324 chr2:102932814 G/A cg09003973 chr2:102972529 NA 1.4 9.4 0.64 3.64e-16 Gut microbiota (bacterial taxa); TGCT cis rs1215050 0.791 rs7688942 chr4:98832048 T/C cg17366294 chr4:99064904 C4orf37 0.57 6.14 0.48 1.04e-8 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs17685 0.753 rs2302438 chr7:75677065 C/A cg19862616 chr7:65841803 NCRNA00174 0.52 8.84 0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs3820068 0.603 rs41270279 chr1:15988878 A/G cg05660106 chr1:15850417 CASP9 0.81 7.67 0.57 4.28e-12 Systolic blood pressure; TGCT cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg11644478 chr21:40555479 PSMG1 1.04 10.72 0.69 2.25e-19 Cognitive function; TGCT cis rs35306767 0.715 rs17221463 chr10:1038040 T/C cg18964960 chr10:1102726 WDR37 0.78 5.4 0.44 3.21e-7 Eosinophil percentage of granulocytes; TGCT cis rs56309584 0.599 rs117347460 chr17:8097171 C/T cg08322244 chr17:8066669 VAMP2 -0.55 -5.19 -0.42 8.23e-7 Initial pursuit acceleration; TGCT cis rs12497850 0.931 rs7616815 chr3:48779715 C/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.64 -0.45 1.1e-7 Parkinson's disease; TGCT cis rs61990749 0.597 rs13379065 chr14:78141295 C/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.65 -0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs12510870 0.599 rs7695946 chr4:74453111 T/A cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs4906332 1.000 rs2065018 chr14:103879187 C/T cg26031613 chr14:104095156 KLC1 0.5 4.57 0.38 1.16e-5 Coronary artery disease; TGCT cis rs6879260 0.963 rs11738924 chr5:179727308 A/G cg13944838 chr5:179740914 GFPT2 -0.38 -5.87 -0.47 3.7e-8 Height; TGCT cis rs8031584 0.958 rs3512 chr15:31235005 G/C cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.28e-6 Huntington's disease progression; TGCT cis rs2692947 0.727 rs749459 chr2:96795714 G/A cg23100626 chr2:96804247 ASTL 0.41 4.9 0.4 2.91e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs3749237 1.000 rs11130216 chr3:49736172 C/A cg03060546 chr3:49711283 APEH 0.74 7.6 0.56 6.37e-12 Resting heart rate; TGCT cis rs5769765 0.865 rs3788730 chr22:50244695 C/T cg22709217 chr22:50311962 ALG12;CRELD2 1.06 11.57 0.72 1.91e-21 Schizophrenia; TGCT cis rs12950390 0.853 rs11079790 chr17:45853626 G/A cg24803719 chr17:45855879 NA -0.48 -4.82 -0.4 4.11e-6 IgG glycosylation; TGCT cis rs67311347 0.544 rs9864664 chr3:40336226 T/C cg13683864 chr3:40499215 RPL14 -0.79 -7.55 -0.56 8.28e-12 Renal cell carcinoma; TGCT cis rs6490294 0.799 rs12426566 chr12:112315172 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg16325326 chr1:53192061 ZYG11B -0.72 -8.65 -0.61 2.28e-14 Monocyte count; TGCT cis rs2046867 0.908 rs62251640 chr3:72801605 T/C cg25664220 chr3:72788482 NA -0.56 -7.03 -0.53 1.25e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.830 rs11722272 chr4:99000839 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.04 0.41 1.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs6686873 chr1:154913404 C/G cg16680214 chr1:154839983 KCNN3 -0.35 -7.11 -0.54 8.04e-11 Prostate cancer; TGCT cis rs9677476 0.516 rs2175147 chr2:232008473 A/G cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs7715806 0.500 rs34355 chr5:74959970 G/A cg19683494 chr5:74908142 NA -0.52 -4.8 -0.4 4.49e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs4253772 0.591 rs11703848 chr22:46685131 A/G cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs735396 1.000 rs1169309 chr12:121439192 G/T cg02403541 chr12:121454288 C12orf43 0.66 6.27 0.49 5.35e-9 N-glycan levels; TGCT cis rs7917772 0.536 rs4919667 chr10:104426011 A/G cg05855489 chr10:104503620 C10orf26 0.59 4.97 0.41 2.18e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9302065 0.681 rs9524902 chr13:95963518 C/T cg26751094 chr13:95954534 ABCC4 -0.34 -5.44 -0.44 2.78e-7 Blood metabolite levels; TGCT cis rs4654899 0.897 rs7548649 chr1:21090081 A/G cg01072550 chr1:21505969 NA -0.49 -7.89 -0.58 1.37e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2617583 0.530 rs905201 chr5:1457986 C/T cg13982541 chr5:1466431 LPCAT1 0.2 4.78 0.39 4.96e-6 Breast cancer; TGCT trans rs77457752 0.525 rs1923350 chr9:13898880 T/A cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.21e-10 Breast cancer; TGCT cis rs12042938 0.507 rs1655299 chr1:231732161 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.62 -6.16 -0.48 9.54e-9 Neuranatomic and neurocognitive phenotypes; TGCT cis rs4478858 0.775 rs6685868 chr1:31706956 C/T cg00250761 chr1:31883323 NA -0.3 -5.52 -0.44 1.88e-7 Alcohol dependence; TGCT cis rs2130392 1.000 rs4862406 chr4:185629339 G/A cg14471096 chr4:185570637 CCDC111;CASP3 -0.57 -5.25 -0.43 6.46e-7 Kawasaki disease; TGCT cis rs9399137 0.507 rs13209780 chr6:135344795 G/C cg24558204 chr6:135376177 HBS1L 0.48 4.97 0.41 2.22e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs1670533 0.932 rs935968 chr4:1063187 G/T cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.55e-8 Recombination rate (females); TGCT cis rs17331151 0.573 rs76029595 chr3:52868523 C/T cg15956490 chr3:53032818 SFMBT1 0.46 5.75 0.46 6.57e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7296418 0.922 rs12425009 chr12:123502044 C/T cg00376283 chr12:123451042 ABCB9 0.86 8.06 0.59 5.57e-13 Platelet count; TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg17775962 chr7:1200435 ZFAND2A 0.27 4.56 0.38 1.21e-5 Longevity;Endometriosis; TGCT cis rs10883723 0.773 rs1326193 chr10:104271674 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7715806 0.500 rs17563610 chr5:74981322 A/T cg19683494 chr5:74908142 NA 0.57 4.95 0.41 2.35e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs2594989 0.733 rs9861286 chr3:11568144 C/T cg00170343 chr3:11313890 ATG7 -0.66 -5.3 -0.43 5.19e-7 Circulating chemerin levels; TGCT cis rs7246657 0.943 rs12709813 chr19:37844983 G/A cg03233940 chr19:37894644 NA -0.34 -4.49 -0.37 1.59e-5 Coronary artery calcification; TGCT cis rs10761750 1 rs10761750 chr10:65128619 G/A cg08743896 chr10:65200160 JMJD1C -0.34 -4.51 -0.38 1.48e-5 Vascular endothelial growth factor levels; TGCT cis rs586688 0.929 rs587180 chr1:201631088 G/A cg05779441 chr1:201574716 NA 0.29 4.7 0.39 6.78e-6 Obesity-related traits; TGCT cis rs2658782 0.951 rs72972364 chr11:93122128 C/T cg18152523 chr11:93063302 CCDC67 0.76 6.25 0.49 6.04e-9 Pulmonary function decline; TGCT trans rs1908814 0.516 rs7825529 chr8:11794444 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs3617 0.625 rs2240917 chr3:52851137 T/C cg11645453 chr3:52864694 ITIH4 0.28 5.45 0.44 2.63e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs77441887 0.636 rs17043283 chr12:77690281 A/T cg12013332 chr12:76741916 BBS10 0.84 4.46 0.37 1.85e-5 Fibroblast growth factor basic levels; TGCT cis rs8180040 0.966 rs60369822 chr3:47479735 A/C cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs1552244 1.000 rs4269070 chr3:10126083 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs6088580 0.634 rs2184836 chr20:32963369 A/G cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs16866061 1.000 rs34345163 chr2:225459080 A/G cg12698349 chr2:225449008 CUL3 1.0 9.4 0.64 3.62e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs6095298 0.557 rs6012538 chr20:47441883 G/A cg12307787 chr20:48099359 KCNB1 0.44 4.67 0.39 7.75e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.932 rs1541061 chr20:25521057 G/A cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3008870 0.755 rs2815349 chr1:67472280 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.81 8.43 0.6 7.53e-14 Lymphocyte percentage of white cells; TGCT cis rs4925386 0.959 rs6121989 chr20:60916713 A/T cg24112000 chr20:60950667 NA 0.35 4.84 0.4 3.85e-6 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs7017914 0.902 rs13269513 chr8:71578079 A/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT trans rs1814175 0.781 rs28681334 chr11:50051177 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs9393692 0.905 rs9393694 chr6:26279296 T/C cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT cis rs7714584 1.000 rs77698001 chr5:150250367 C/T cg22134413 chr5:150180641 NA 0.89 6.87 0.53 2.72e-10 Crohn's disease; TGCT cis rs7246657 0.663 rs9304568 chr19:38054508 C/A cg03611452 chr19:38183253 ZNF781 0.56 4.68 0.39 7.54e-6 Coronary artery calcification; TGCT cis rs875971 0.767 rs1695815 chr7:65831344 A/G cg11764359 chr7:65958608 NA 0.62 5.57 0.45 1.51e-7 Aortic root size; TGCT cis rs9611565 0.694 rs9611591 chr22:41830212 G/A cg13695892 chr22:41940480 POLR3H 0.85 8.53 0.61 4.33e-14 Vitiligo; TGCT cis rs7772486 0.811 rs2777475 chr6:146304603 G/A cg23711669 chr6:146136114 FBXO30 0.7 6.38 0.5 3.2e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7829975 0.514 rs2976926 chr8:8261624 T/C cg15556689 chr8:8085844 FLJ10661 0.75 6.78 0.52 4.26e-10 Mood instability; TGCT cis rs7829975 0.522 rs6601689 chr8:8172283 C/T cg06636001 chr8:8085503 FLJ10661 0.54 4.87 0.4 3.37e-6 Mood instability; TGCT cis rs4722166 0.541 rs1800795 chr7:22766645 C/G cg13104385 chr7:22767384 IL6 0.21 4.88 0.4 3.19e-6 Lung cancer; TGCT cis rs2721195 0.626 rs59464125 chr8:145857786 G/A cg11211951 chr8:145729740 GPT -0.21 -4.72 -0.39 6.28e-6 Age at first birth; TGCT cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg03517284 chr6:25882590 NA -1.08 -13.96 -0.78 3.4e-27 Urate levels; TGCT cis rs2075371 1.000 rs2244700 chr7:133987374 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.39e-9 Mean platelet volume; TGCT cis rs10256972 0.567 rs2960850 chr7:1211649 A/G cg03188948 chr7:1209495 NA 0.45 5.7 0.46 8.09e-8 Longevity;Endometriosis; TGCT cis rs7659604 0.539 rs3217753 chr4:122746325 A/G cg19748678 chr4:122722346 EXOSC9 0.88 8.89 0.62 5.97e-15 Type 2 diabetes; TGCT cis rs11671005 0.737 rs11671033 chr19:58963669 G/T cg18639983 chr19:58920768 ZNF584 0.33 4.54 0.38 1.34e-5 Mean platelet volume; TGCT cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs950169 0.919 rs12915589 chr15:84734464 T/C cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.14e-8 Schizophrenia; TGCT cis rs9926296 0.512 rs11076626 chr16:89865103 T/A cg27121462 chr16:89883253 FANCA 0.79 8.71 0.62 1.62e-14 Vitiligo; TGCT cis rs12579753 0.917 rs7954438 chr12:82184419 T/C cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT trans rs8073060 0.544 rs225244 chr17:33946581 A/G cg19694781 chr19:47549865 TMEM160 0.6 13.04 0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg16590910 chr6:42928470 GNMT -0.49 -4.52 -0.38 1.41e-5 Plasma homocysteine levels (post-methionine load test); TGCT cis rs1371867 0.846 rs1660328 chr8:101303450 A/G cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs7582180 0.629 rs12612809 chr2:100951616 G/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs769267 0.965 rs12977937 chr19:19429975 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.72 6.45 0.5 2.28e-9 Tonsillectomy; TGCT trans rs28735056 1.000 rs4798922 chr18:77628953 G/C cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT cis rs3617 0.573 rs2336668 chr3:52919096 G/T cg10802521 chr3:52805072 NEK4 0.57 6.57 0.51 1.27e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9653442 0.675 rs12995420 chr2:100652578 T/C cg22139774 chr2:100720529 AFF3 -0.41 -7.3 -0.55 3.02e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9549367 0.865 rs3861721 chr13:113906308 C/T cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs727563 0.594 rs132807 chr22:42071584 T/C cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1511802 0.591 rs6810892 chr4:187123941 C/T cg19358738 chr4:186734530 SORBS2 0.17 4.43 0.37 2.01e-5 Blood protein levels; TGCT cis rs769267 0.929 rs2905421 chr19:19457908 G/T cg03709012 chr19:19516395 GATAD2A 0.66 5.68 0.45 9.28e-8 Tonsillectomy; TGCT cis rs9611565 0.592 rs9611612 chr22:41961189 T/C cg06481639 chr22:41940642 POLR3H -0.67 -5.8 -0.46 5.24e-8 Vitiligo; TGCT cis rs11764561 0.503 rs1922086 chr7:156016226 C/T cg13324311 chr7:156111445 NA -0.26 -4.49 -0.37 1.62e-5 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg13683864 chr3:40499215 RPL14 -1.1 -11.83 -0.73 4.49e-22 Renal cell carcinoma; TGCT cis rs12643440 0.538 rs62296684 chr4:17137455 A/T cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT trans rs1814175 0.588 rs10466497 chr11:49864381 A/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs2921036 0.529 rs2979192 chr8:8338147 C/T cg06636001 chr8:8085503 FLJ10661 0.64 5.66 0.45 1.01e-7 Neuroticism; TGCT cis rs447735 0.537 rs7190341 chr16:89917537 T/C cg26513180 chr16:89883248 FANCA 0.7 6.13 0.48 1.09e-8 Hemoglobin concentration; TGCT cis rs7940866 0.874 rs7111478 chr11:130819628 A/G cg05962950 chr11:130786565 SNX19 0.68 6.93 0.53 2.03e-10 Schizophrenia; TGCT cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg15857475 chr8:145742913 RECQL4;LRRC14 -0.85 -9.23 -0.64 9.23e-16 Age at first birth; TGCT cis rs2932538 0.922 rs12402929 chr1:113072293 G/C cg22162597 chr1:113214053 CAPZA1 0.28 6.0 0.47 1.99e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9788682 0.948 rs905739 chr15:78845110 A/G cg06917634 chr15:78832804 PSMA4 -0.69 -4.69 -0.39 7.24e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2361718 0.500 rs4889818 chr17:78085228 A/G cg17882374 chr17:78041429 CCDC40 0.29 4.64 0.38 8.71e-6 Yeast infection; TGCT cis rs4478858 0.735 rs6425737 chr1:31790288 T/C cg00250761 chr1:31883323 NA -0.27 -4.84 -0.4 3.76e-6 Alcohol dependence; TGCT trans rs62103177 0.673 rs36087369 chr18:77589596 C/G cg05926928 chr17:57297772 GDPD1 1.03 9.74 0.66 5.52e-17 Opioid sensitivity; TGCT cis rs2702888 0.501 rs2702936 chr8:6751434 T/C cg26795848 chr8:6756730 NA -0.31 -6.21 -0.49 7.26e-9 Blood pressure; TGCT cis rs76866386 1.000 rs4953023 chr2:44074000 C/T cg18957751 chr2:43448938 NA -0.65 -4.67 -0.39 7.8e-6 Cholesterol, total; TGCT cis rs1153858 1.000 rs4775909 chr15:45643042 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.03 0.8 1.02e-29 Homoarginine levels; TGCT cis rs11098499 0.562 rs2389879 chr4:120557684 G/A cg09307838 chr4:120376055 NA -0.57 -5.3 -0.43 5.13e-7 Corneal astigmatism; TGCT cis rs6598955 0.543 rs881578 chr1:26536141 G/A cg24519413 chr1:26490540 NA -0.25 -4.61 -0.38 9.99e-6 Obesity-related traits; TGCT cis rs67311347 0.568 rs9864544 chr3:40336204 T/C cg13683864 chr3:40499215 RPL14 -0.79 -7.55 -0.56 8.28e-12 Renal cell carcinoma; TGCT cis rs9309473 0.539 rs7574268 chr2:73904872 C/T cg20560298 chr2:73613845 ALMS1 0.43 4.66 0.39 7.98e-6 Metabolite levels; TGCT cis rs589249 0.825 rs4653213 chr1:37179503 C/A cg04012535 chr1:37176647 NA 0.36 5.65 0.45 1.03e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs909674 0.541 rs5750812 chr22:39793079 G/A cg02038168 chr22:39784481 NA -0.74 -6.44 -0.5 2.36e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs739496 0.579 rs10849984 chr12:112347728 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs514406 0.861 rs35581164 chr1:53271373 C/G cg08859206 chr1:53392774 SCP2 -0.38 -5.72 -0.46 7.61e-8 Monocyte count; TGCT cis rs1215050 0.740 rs700739 chr4:99022546 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.99 -0.41 1.95e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2835872 0.869 rs73203821 chr21:39046744 C/T cg20424643 chr21:39039972 KCNJ6 0.23 4.64 0.38 8.75e-6 Electroencephalographic traits in alcoholism; TGCT cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg03161606 chr19:29218774 NA 0.56 6.06 0.48 1.51e-8 Methadone dose in opioid dependence; TGCT cis rs427394 1.000 rs182135 chr5:6747453 G/A cg10857441 chr5:6722123 POLS -0.27 -6.63 -0.51 9.35e-10 Menopause (age at onset); TGCT cis rs4144743 1.000 rs4144745 chr17:45323349 T/C cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs707040 0.810 rs6435165 chr2:155218550 T/G cg18104148 chr2:154337490 NA 0.19 4.79 0.4 4.63e-6 Sudden cardiac arrest; TGCT cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.5 -4.75 -0.39 5.6e-6 Prudent dietary pattern; TGCT trans rs10506458 0.915 rs12426017 chr12:63396272 T/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs1541995 0.754 rs71396826 chr15:96236968 T/G cg00882281 chr15:96346592 NA 0.3 4.63 0.38 9.12e-6 Photic sneeze reflex; TGCT cis rs9928842 0.679 rs4888361 chr16:75267676 A/G cg09066997 chr16:75300724 BCAR1 0.28 5.09 0.42 1.31e-6 Alcoholic chronic pancreatitis; TGCT cis rs410644 0.717 rs436064 chr5:81069494 C/T cg09496599 chr5:80383224 RASGRF2 -0.16 -4.65 -0.39 8.39e-6 Anorexia nervosa; TGCT cis rs41271951 0.542 rs11584761 chr1:150250991 G/A cg18798344 chr1:149336151 NA 0.56 4.5 0.37 1.52e-5 Blood protein levels; TGCT cis rs3782455 0.793 rs2290801 chr12:114404424 C/G cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10927875 0.632 rs4661666 chr1:16162471 C/A cg14742211 chr1:16348397 CLCNKA -0.2 -4.79 -0.39 4.75e-6 Dilated cardiomyopathy; TGCT cis rs2404602 0.716 rs8030411 chr15:76699855 A/G cg26408565 chr15:76604113 ETFA -0.43 -5.76 -0.46 6.17e-8 Blood metabolite levels; TGCT cis rs2458413 0.542 rs2514669 chr8:105362842 A/C cg04554929 chr8:105342491 NA 0.49 5.88 0.47 3.59e-8 Paget's disease; TGCT cis rs2650000 0.536 rs1169286 chr12:121419056 T/C cg02403541 chr12:121454288 C12orf43 0.58 5.55 0.45 1.65e-7 Metabolic traits;LDL cholesterol; TGCT cis rs911555 0.755 rs2756132 chr14:103967820 C/G cg12935359 chr14:103987150 CKB 0.33 4.59 0.38 1.05e-5 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs6872854 chr5:209038 G/T cg22857025 chr5:266934 NA -0.32 -6.4 -0.5 2.83e-9 Breast cancer; TGCT cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg11644478 chr21:40555479 PSMG1 -1.05 -10.79 -0.7 1.53e-19 Cognitive function; TGCT cis rs10088262 0.629 rs7015861 chr8:124795613 C/T cg20713898 chr8:124780851 FAM91A1 -0.83 -7.14 -0.54 6.79e-11 Pancreatic cancer; TGCT cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 8.56 0.61 3.72e-14 Platelet count; TGCT cis rs1843834 0.721 rs6436507 chr2:225598242 T/A cg22455342 chr2:225449267 CUL3 0.65 6.26 0.49 5.64e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs6880778 0.505 rs10072596 chr5:40407033 A/G cg01087697 chr5:40835557 RPL37 0.55 4.96 0.41 2.22e-6 Inflammatory bowel disease; TGCT cis rs6901004 0.803 rs168522 chr6:111506628 A/G cg15721981 chr6:111408429 SLC16A10 -0.53 -4.64 -0.38 8.82e-6 Blood metabolite levels; TGCT cis rs9926296 0.609 rs4785714 chr16:89798404 G/T cg26513180 chr16:89883248 FANCA -0.68 -6.56 -0.51 1.29e-9 Vitiligo; TGCT cis rs6951245 0.935 rs11763765 chr7:1060510 C/T cg18402987 chr7:1209562 NA 0.65 5.32 0.43 4.65e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4566357 1.000 rs2396444 chr2:227921314 T/G cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs568617 0.716 rs77779142 chr11:65599656 C/T cg04055107 chr11:65626734 MUS81;CFL1 0.64 5.1 0.42 1.22e-6 Crohn's disease; TGCT trans rs62103177 0.608 rs4799115 chr18:77736365 A/T cg05926928 chr17:57297772 GDPD1 -0.77 -6.81 -0.52 3.73e-10 Opioid sensitivity; TGCT cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs2562456 0.516 rs56072098 chr19:21651960 G/T cg25650185 chr19:21324782 ZNF431 0.54 4.68 0.39 7.27e-6 Pain; TGCT cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg06481639 chr22:41940642 POLR3H 0.71 6.43 0.5 2.56e-9 Vitiligo; TGCT cis rs875971 0.862 rs10276077 chr7:65728411 A/G cg11764359 chr7:65958608 NA -0.57 -5.12 -0.42 1.12e-6 Aortic root size; TGCT cis rs6582630 0.502 rs1115515 chr12:38279830 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.67 0.39 7.69e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs922182 0.607 rs8030264 chr15:64271496 C/T cg02919090 chr15:64263738 DAPK2 -0.29 -5.21 -0.42 7.69e-7 Blood protein levels; TGCT cis rs7975161 0.630 rs4964732 chr12:104652705 A/T cg25273343 chr12:104657179 TXNRD1 -0.47 -5.85 -0.46 4.13e-8 Toenail selenium levels; TGCT cis rs2637266 0.875 rs115333453 chr10:78369011 G/A cg18941641 chr10:78392320 NA 0.43 5.57 0.45 1.49e-7 Pulmonary function; TGCT cis rs950169 0.763 rs35372971 chr15:84941795 G/A cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT trans rs7613875 0.600 rs1138536 chr3:50153356 C/T cg21659725 chr3:3221576 CRBN 0.67 7.24 0.55 4.07e-11 Body mass index; TGCT cis rs8177253 1.000 rs8177248 chr3:133479626 C/T cg08048268 chr3:133502702 NA -0.63 -8.65 -0.61 2.25e-14 Iron status biomarkers; TGCT cis rs2880765 0.805 rs11858817 chr15:86031260 C/T cg13263323 chr15:86062960 AKAP13 -0.22 -4.79 -0.4 4.68e-6 Coronary artery disease; TGCT cis rs10986311 0.802 rs3780201 chr9:127104775 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.65 -0.39 8.24e-6 Vitiligo; TGCT cis rs10927875 0.632 rs10927864 chr1:16165661 C/G cg21385522 chr1:16154831 NA -1.01 -18.14 -0.85 1.06e-36 Dilated cardiomyopathy; TGCT cis rs9902453 0.904 rs9900112 chr17:28282910 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.82 7.62 0.56 5.54e-12 Coffee consumption (cups per day); TGCT cis rs9905704 0.647 rs2286299 chr17:57043367 T/G cg05425664 chr17:57184151 TRIM37 -0.58 -4.68 -0.39 7.49e-6 Testicular germ cell tumor; TGCT cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg21433313 chr16:3507492 NAT15 0.37 4.74 0.39 5.76e-6 Tuberculosis; TGCT cis rs12477438 0.520 rs6717729 chr2:99756941 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.85 8.52 0.61 4.53e-14 Chronic sinus infection; TGCT cis rs1153858 1.000 rs7402650 chr15:45701895 C/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.67 0.45 9.65e-8 Homoarginine levels; TGCT cis rs11105298 0.891 rs3741898 chr12:89933763 G/C cg00757033 chr12:89920650 WDR51B 0.29 4.6 0.38 1.01e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9443645 0.901 rs10455356 chr6:79664748 T/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs1005277 0.579 rs2505240 chr10:38442419 G/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.23 -0.59 2.17e-13 Extrinsic epigenetic age acceleration; TGCT trans rs1496653 0.602 rs36082634 chr3:23554688 G/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs10901296 0.702 rs11244178 chr9:133766008 C/T cg01000188 chr9:133769184 QRFP -0.33 -4.5 -0.37 1.55e-5 Bilirubin levels; TGCT cis rs7647973 0.925 rs6446257 chr3:49253492 A/G cg06212747 chr3:49208901 KLHDC8B -0.61 -5.14 -0.42 1.06e-6 Menarche (age at onset); TGCT cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.62 0.56 5.6e-12 Schizophrenia; TGCT cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg18305652 chr10:134549665 INPP5A 0.35 5.93 0.47 2.87e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs564343 0.545 rs2241303 chr11:65819661 C/A cg26701943 chr11:108369231 KDELC2 -0.74 -6.87 -0.53 2.81e-10 Obesity (early onset extreme); TGCT cis rs7267979 1.000 rs6083844 chr20:25386832 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1729951 0.575 rs1654904 chr3:136681149 T/C cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs3791556 0.853 rs35245395 chr2:240107661 C/T cg03281426 chr2:240109471 HDAC4 0.28 4.79 0.39 4.76e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.648 rs3774354 chr3:52817675 G/A cg10802521 chr3:52805072 NEK4 -0.71 -8.43 -0.6 7.23e-14 Bipolar disorder; TGCT cis rs3617 0.625 rs3774364 chr3:52863605 G/A cg11645453 chr3:52864694 ITIH4 0.26 4.86 0.4 3.42e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs11585357 0.843 rs113593167 chr1:17613355 G/A cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs1371867 0.846 rs1788180 chr8:101333368 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs7914558 1.000 rs10786740 chr10:104935593 G/C cg04362960 chr10:104952993 NT5C2 0.61 5.45 0.44 2.6e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3020333 0.875 rs3020331 chr6:152008780 C/T cg22157087 chr6:152012887 ESR1 0.2 4.83 0.4 4.01e-6 Total body bone mineral density; TGCT cis rs60733400 0.667 rs4385650 chr1:2499898 G/A cg18854424 chr1:2615690 NA 0.43 4.81 0.4 4.3e-6 Multiple sclerosis; TGCT cis rs13191362 0.938 rs13213746 chr6:163167777 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.88 7.89 0.58 1.34e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6831352 0.918 rs34876213 chr4:100062216 G/A cg12011299 chr4:100065546 ADH4 -0.42 -5.05 -0.41 1.56e-6 Alcohol dependence; TGCT cis rs4901869 0.864 rs12891575 chr14:59334342 T/A cg02291164 chr14:59296302 NA 0.24 4.62 0.38 9.4e-6 Panic disorder; TGCT cis rs12681288 0.823 rs2701906 chr8:1003316 T/C cg04851639 chr8:1020857 NA -0.36 -6.47 -0.5 2.01e-9 Schizophrenia; TGCT trans rs6089829 0.962 rs6122352 chr20:61668284 T/C cg13615516 chr5:77269221 NA 0.67 8.38 0.6 9.45e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg10802521 chr3:52805072 NEK4 -0.78 -9.99 -0.67 1.3e-17 Bipolar disorder; TGCT cis rs6049375 1.000 rs6036631 chr20:24046423 A/G cg14741141 chr20:24973699 C20orf3 0.84 4.92 0.4 2.68e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs2832191 0.791 rs9983651 chr21:30491227 T/A cg08807101 chr21:30365312 RNF160 -0.62 -5.74 -0.46 6.74e-8 Dental caries; TGCT cis rs801193 0.636 rs10233806 chr7:66118248 G/C cg11764359 chr7:65958608 NA -0.57 -4.86 -0.4 3.5e-6 Aortic root size; TGCT cis rs9381040 0.655 rs2268194 chr6:41024447 T/C cg03526776 chr6:41159608 TREML2 0.27 5.29 0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs9790314 0.586 rs11710916 chr3:161130070 A/G cg03342759 chr3:160939853 NMD3 -0.55 -5.7 -0.46 8.15e-8 Morning vs. evening chronotype; TGCT cis rs1372520 0.684 rs184810 chr4:90697979 T/C cg14346243 chr4:90757452 SNCA 0.62 5.29 0.43 5.26e-7 Neuroticism; TGCT cis rs892961 0.899 rs312911 chr17:75414585 A/C cg05865280 chr17:75406074 SEPT9 0.28 6.73 0.52 5.56e-10 Airflow obstruction; TGCT cis rs6952808 0.595 rs3800916 chr7:2166072 C/T cg04267008 chr7:1944627 MAD1L1 -0.37 -5.03 -0.41 1.71e-6 Bipolar disorder and schizophrenia; TGCT cis rs10540 1.000 rs12419766 chr11:503710 C/T cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT trans rs6561151 0.957 rs1932990 chr13:44460242 C/T cg12856521 chr11:46389249 DGKZ 0.63 6.88 0.53 2.6200000000000003e-10 Crohn's disease; TGCT cis rs6088580 0.713 rs1884669 chr20:33171287 G/A cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Glomerular filtration rate (creatinine); TGCT cis rs72781680 0.898 rs72782136 chr2:24047344 A/G cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs7552404 0.696 rs10518521 chr1:76461214 G/A cg10523679 chr1:76189770 ACADM 0.81 6.84 0.52 3.19e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2749592 0.550 rs7917262 chr10:37874602 A/C cg25427524 chr10:38739819 LOC399744 0.3 5.53 0.44 1.79e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs1555895 0.566 rs11253451 chr10:852885 C/T cg02193355 chr10:851439 NA 0.2 4.51 0.38 1.47e-5 Survival in rectal cancer; TGCT cis rs62064224 0.791 rs11656289 chr17:30761160 T/C cg25809561 chr17:30822961 MYO1D 0.28 4.71 0.39 6.66e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs6854919 chr4:98947326 C/T cg05340658 chr4:99064831 C4orf37 0.47 5.19 0.42 8.24e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7043114 0.525 rs10992374 chr9:95336327 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.19 -0.42 8.23e-7 Height; TGCT cis rs7226408 0.857 rs72894323 chr18:34710125 A/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs611744 0.517 rs62537573 chr8:109269281 C/T cg21045802 chr8:109455806 TTC35 0.82 8.65 0.61 2.19e-14 Dupuytren's disease; TGCT cis rs12595025 1 rs12595025 chr15:91520131 C/T cg22570213 chr15:91497863 RCCD1 0.49 4.77 0.39 5e-6 Mean platelet volume; TGCT cis rs3793917 0.948 rs3750846 chr10:124215565 T/C cg09507567 chr10:124027408 NA 0.38 4.71 0.39 6.62e-6 Age-related macular degeneration; TGCT cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg15687855 chr3:44754131 ZNF502 -0.44 -5.27 -0.43 5.87e-7 Depressive symptoms; TGCT cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.563 rs1796688 chr6:8536423 A/T cg07606381 chr6:8435919 SLC35B3 0.54 4.83 0.4 3.9e-6 Motion sickness; TGCT cis rs2692947 0.599 rs7561198 chr2:96774981 C/G cg05933789 chr2:97190408 NA -0.16 -4.74 -0.39 5.75e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2354432 0.660 rs10751415 chr1:146830785 T/A cg25205988 chr1:146714368 CHD1L 1.36 6.23 0.49 6.77e-9 Mitochondrial DNA levels; TGCT cis rs2014572 0.967 rs10413671 chr19:57763489 G/A cg24459738 chr19:57751996 ZNF805 -0.58 -5.7 -0.46 8.38e-8 Hyperactive-impulsive symptoms; TGCT cis rs2013441 1.000 rs2703817 chr17:20119677 A/C cg18979559 chr17:20280153 CCDC144C -0.42 -4.48 -0.37 1.67e-5 Obesity-related traits; TGCT cis rs826838 0.967 rs1719853 chr12:39128515 A/G cg13010199 chr12:38710504 ALG10B -0.59 -4.66 -0.39 8.16e-6 Heart rate; TGCT cis rs9325144 0.647 rs17518186 chr12:38883665 T/C cg10518543 chr12:38710700 ALG10B -0.49 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs7666738 0.830 rs9307218 chr4:99024885 T/C cg05340658 chr4:99064831 C4orf37 0.51 5.82 0.46 4.75e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1577917 1.000 rs7766645 chr6:86622238 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs644799 0.610 rs1255179 chr11:95472097 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.51 5.17 0.42 9.05e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9534288 0.700 rs7331032 chr13:46609040 C/T cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT trans rs629535 0.859 rs55803226 chr8:70108965 T/C cg21567404 chr3:27674614 NA -0.55 -8.44 -0.6 6.92e-14 Dupuytren's disease; TGCT cis rs11098499 0.663 rs28369503 chr4:120238925 G/A cg09307838 chr4:120376055 NA 0.63 6.22 0.49 7.01e-9 Corneal astigmatism; TGCT cis rs263156 0.903 rs263116 chr6:142885834 G/A cg18419694 chr6:143832440 FUCA2 -0.4 -4.71 -0.39 6.56e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs6671200 0.850 rs259345 chr1:95729649 A/G cg03123541 chr1:95699097 RWDD3 -0.91 -6.4 -0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs6759518 0.655 rs1659700 chr2:27414134 T/C cg26210250 chr2:26863503 CIB4 -0.78 -4.46 -0.37 1.79e-5 Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs950169 1.000 rs11638297 chr15:84782417 A/C cg11189052 chr15:85197271 WDR73 0.64 5.3 0.43 5.13e-7 Schizophrenia; TGCT cis rs72945132 0.714 rs66542029 chr11:70196302 A/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs394563 0.591 rs237019 chr6:149727064 G/A cg16235748 chr6:149772707 ZC3H12D -0.44 -4.92 -0.4 2.74e-6 Dupuytren's disease; TGCT cis rs2147959 0.941 rs4653960 chr1:228631719 T/C cg22700015 chr1:228743131 NA -0.56 -4.61 -0.38 9.67e-6 Adult asthma; TGCT cis rs11688237 0.601 rs12613801 chr2:144548368 G/A cg07409629 chr2:144282743 ARHGAP15 -0.38 -4.71 -0.39 6.43e-6 Chin dimples; TGCT cis rs1048466 0.664 rs2041298 chr12:539038 C/G cg26458557 chr12:285704 IQSEC3 -0.24 -4.5 -0.37 1.56e-5 Obesity (early onset extreme); TGCT cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg05665937 chr4:1216051 CTBP1 0.25 4.7 0.39 6.84e-6 Obesity-related traits; TGCT cis rs7267979 0.966 rs2261720 chr20:25260641 T/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg20607798 chr8:58055168 NA 0.49 4.52 0.38 1.43e-5 Developmental language disorder (linguistic errors); TGCT cis rs2204008 0.744 rs1115514 chr12:38280140 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.33 0.55 2.58e-11 Bladder cancer; TGCT cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6558530 0.666 rs4242538 chr8:1694010 G/C cg09410841 chr8:1729607 CLN8 0.64 5.7 0.46 8.43e-8 Systolic blood pressure; TGCT cis rs910316 0.726 rs61979167 chr14:75663610 C/T cg11812906 chr14:75593930 NEK9 -0.61 -5.5 -0.44 2.04e-7 Height; TGCT cis rs478304 0.934 rs506853 chr11:65521247 C/T cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.01e-7 Acne (severe); TGCT cis rs2456568 0.802 rs1108910 chr11:93629677 C/T cg14065697 chr11:93583672 C11orf90 0.39 4.79 0.4 4.69e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6088580 0.634 rs2424992 chr20:33012060 C/T cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs854765 0.647 rs6826 chr17:18011140 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.72 7.52 0.56 9.79e-12 Total body bone mineral density; TGCT cis rs78456975 0.941 rs6755875 chr2:1557109 T/C cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs3862435 0.764 rs28545005 chr15:90954131 A/G cg14166756 chr15:90894880 ZNF774 -0.29 -4.68 -0.39 7.31e-6 Response to exercise (triglyceride level interaction); TGCT cis rs6430585 0.793 rs11684545 chr2:136539122 G/T cg07169764 chr2:136633963 MCM6 -0.68 -6.21 -0.49 7.42e-9 Corneal structure; TGCT cis rs13191362 1.000 rs34066731 chr6:163011047 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7943203 0.524 rs227060 chr11:108204881 C/T cg04873221 chr11:107992290 ACAT1 -0.61 -5.18 -0.42 8.85e-7 Red blood cell count;Mean corpuscular volume; TGCT cis rs7914558 1.000 rs12780843 chr10:104769335 G/C cg04362960 chr10:104952993 NT5C2 0.6 5.36 0.43 3.97e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12477438 0.539 rs12999417 chr2:99865548 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -1.0 -12.33 -0.74 2.72e-23 Chronic sinus infection; TGCT cis rs2832191 0.791 rs2065270 chr21:30485420 T/C cg24692254 chr21:30365293 RNF160 -0.95 -10.52 -0.69 7.01e-19 Dental caries; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg16325326 chr1:53192061 ZYG11B 0.52 5.95 0.47 2.6e-8 Monocyte count; TGCT cis rs933688 1.000 rs1363839 chr5:90671274 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 9.41 0.65 3.47e-16 Smoking behavior; TGCT cis rs801193 0.569 rs2707824 chr7:66189243 A/G cg11764359 chr7:65958608 NA 0.54 4.85 0.4 3.67e-6 Aortic root size; TGCT cis rs9818758 0.607 rs34326553 chr3:49134429 A/G cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs769267 0.864 rs7245983 chr19:19657632 A/C cg03709012 chr19:19516395 GATAD2A 0.69 5.65 0.45 1.06e-7 Tonsillectomy; TGCT cis rs3796352 0.881 rs34238610 chr3:53026480 A/T cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg13395646 chr4:1353034 KIAA1530 -0.36 -4.75 -0.39 5.64e-6 Obesity-related traits; TGCT cis rs5750830 0.621 rs743838 chr22:39824707 T/G cg01416388 chr22:39784598 NA -0.7 -6.92 -0.53 2.11e-10 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.545 rs12987212 chr2:100761156 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.31 -0.43 4.89e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.79e-5 Obesity-related traits; TGCT cis rs2115630 1.000 rs4633690 chr15:85361960 C/T cg17173187 chr15:85201210 NMB -0.41 -4.93 -0.4 2.61e-6 P wave terminal force; TGCT cis rs7246657 0.882 rs6508719 chr19:37877419 A/G cg18154014 chr19:37997991 ZNF793 0.74 5.33 0.43 4.48e-7 Coronary artery calcification; TGCT cis rs9567349 1.000 rs9567352 chr13:44637493 C/T cg12694124 chr13:45013657 TSC22D1 -0.46 -4.65 -0.39 8.2e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 0.679 rs12679920 chr8:58051710 G/T cg20607798 chr8:58055168 NA 0.44 4.6 0.38 1.01e-5 Developmental language disorder (linguistic errors); TGCT cis rs6964587 0.633 rs13231620 chr7:91507859 G/A cg17063962 chr7:91808500 NA -0.84 -8.62 -0.61 2.6e-14 Breast cancer; TGCT cis rs1790761 0.501 rs4930210 chr11:67404726 G/T cg23188684 chr11:67383651 NA -0.33 -5.12 -0.42 1.16e-6 Mean corpuscular volume; TGCT cis rs7727544 0.606 rs10060615 chr5:131708877 T/C cg14196790 chr5:131705035 SLC22A5 0.34 4.67 0.39 7.69e-6 Blood metabolite levels; TGCT cis rs9325144 0.624 rs7312879 chr12:39150752 G/A cg26384229 chr12:38710491 ALG10B -0.61 -5.69 -0.46 8.63e-8 Morning vs. evening chronotype; TGCT cis rs1568889 0.592 rs17652117 chr11:28483645 C/T cg06544937 chr11:28130018 METT5D1;KIF18A -0.7 -5.65 -0.45 1.06e-7 Bipolar disorder; TGCT cis rs7267979 1.000 rs4813566 chr20:25386465 G/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7829975 0.533 rs35900578 chr8:8719513 G/A cg15556689 chr8:8085844 FLJ10661 0.74 6.66 0.51 8.04e-10 Mood instability; TGCT cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg00343986 chr7:65444356 GUSB 0.22 5.38 0.44 3.53e-7 Calcium levels; TGCT cis rs7826238 0.543 rs2976908 chr8:8345774 T/G cg06636001 chr8:8085503 FLJ10661 0.59 5.04 0.41 1.59e-6 Systolic blood pressure; TGCT cis rs3126085 0.867 rs11204948 chr1:152218473 A/G cg03465714 chr1:152285911 FLG -0.41 -4.79 -0.39 4.75e-6 Atopic dermatitis; TGCT cis rs8050907 0.744 rs17879291 chr16:4526104 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs2282802 0.660 rs2436390 chr5:139586501 G/A cg01081189 chr5:139537190 NA -0.29 -5.41 -0.44 3.19e-7 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs796364 1.000 rs1658807 chr2:200767512 C/T cg17644776 chr2:200775616 C2orf69 0.31 4.76 0.39 5.39e-6 Schizophrenia; TGCT cis rs933688 1.000 rs12656350 chr5:90751343 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.03 8.55 0.61 3.8e-14 Smoking behavior; TGCT cis rs4851254 0.660 rs74340261 chr2:100696827 C/T cg04109781 chr2:100722022 AFF3 0.46 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg11211951 chr8:145729740 GPT -0.24 -5.7 -0.46 8.4e-8 Age at first birth; TGCT cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs933688 0.532 rs997737 chr5:90567031 C/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.56 -4.73 -0.39 5.91e-6 Smoking behavior; TGCT cis rs7666738 0.830 rs1593569 chr4:99017485 C/G cg05340658 chr4:99064831 C4orf37 0.49 5.62 0.45 1.18e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs929354 0.742 rs3808317 chr7:156944460 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs9473924 0.542 rs2245173 chr6:50810540 T/C cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs7107174 0.892 rs4291702 chr11:78001248 C/T cg12700464 chr11:78128424 GAB2 -0.63 -4.49 -0.37 1.62e-5 Testicular germ cell tumor; TGCT cis rs5769765 1.000 rs4824106 chr22:50267822 T/C cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs12615966 0.932 rs4013898 chr2:105369671 C/T cg16465502 chr2:105461796 NA 0.78 4.54 0.38 1.29e-5 Pancreatic cancer; TGCT cis rs12286929 0.610 rs12807135 chr11:115053508 G/C cg04017736 chr11:115827165 NA -0.21 -4.7 -0.39 6.78e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg07167872 chr1:205819463 PM20D1 0.66 9.2 0.64 1.07e-15 Menarche (age at onset); TGCT cis rs78456975 1.000 rs72776251 chr2:1525097 G/A cg01028140 chr2:1542097 TPO -0.35 -4.67 -0.39 7.82e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs67478160 0.584 rs2295148 chr14:104195610 T/C cg01849466 chr14:104193079 ZFYVE21 -0.19 -4.61 -0.38 9.97e-6 Schizophrenia; TGCT cis rs597539 0.654 rs619727 chr11:68627535 A/G cg04772025 chr11:68637568 NA 0.6 6.78 0.52 4.36e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7208859 0.623 rs7219361 chr17:29080393 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10986311 0.775 rs10760359 chr9:127174353 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -4.87 -0.4 3.37e-6 Vitiligo; TGCT cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 9.05e-28 Menopause (age at onset); TGCT cis rs17376456 0.569 rs35878747 chr5:93094070 C/A cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT cis rs5769765 0.908 rs4074304 chr22:50309446 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.44 6.24 0.49 6.27e-9 Schizophrenia; TGCT trans rs1005277 0.603 rs1998062 chr10:38457652 G/C cg27523141 chr10:43048294 ZNF37B 0.74 8.61 0.61 2.7e-14 Extrinsic epigenetic age acceleration; TGCT cis rs782590 0.517 rs13013133 chr2:55889466 G/A cg18811423 chr2:55921094 PNPT1 -0.6 -5.19 -0.42 8.37e-7 Metabolic syndrome; TGCT cis rs8031584 0.752 rs2001686 chr15:31185772 G/A cg08704250 chr15:31115839 NA -0.42 -6.28 -0.49 5.27e-9 Huntington's disease progression; TGCT cis rs4665809 0.590 rs2289019 chr2:26420809 G/C cg26119090 chr2:26468346 HADHA;HADHB -0.93 -6.89 -0.53 2.52e-10 Gut microbiome composition (summer); TGCT cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg11644478 chr21:40555479 PSMG1 0.65 6.04 0.48 1.65e-8 Cognitive function; TGCT cis rs597539 0.615 rs629426 chr11:68671104 A/G cg04772025 chr11:68637568 NA 0.6 6.77 0.52 4.48e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs600231 0.706 rs3782091 chr11:65336483 G/T cg17120908 chr11:65337727 SSSCA1 0.57 5.78 0.46 5.72e-8 Bone mineral density; TGCT cis rs2762353 0.574 rs4409177 chr6:25694491 T/G cg15691649 chr6:25882328 NA 0.52 6.06 0.48 1.51e-8 Blood metabolite levels; TGCT cis rs6728642 0.572 rs60621865 chr2:97598001 T/C cg26665480 chr2:98280029 ACTR1B -0.94 -6.74 -0.52 5.4e-10 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs782590 0.783 rs7594279 chr2:55812073 T/G cg18811423 chr2:55921094 PNPT1 0.64 6.67 0.51 7.52e-10 Metabolic syndrome; TGCT cis rs10743315 0.599 rs11044451 chr12:19365798 C/T cg02471346 chr12:19282374 PLEKHA5 -0.61 -4.59 -0.38 1.06e-5 Gut microbiota (bacterial taxa); TGCT cis rs4845570 0.920 rs10788809 chr1:151760792 A/G cg07092448 chr1:151763213 TDRKH 1.19 9.81 0.66 3.59e-17 Coronary artery disease; TGCT cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.920 rs2905881 chr17:29547862 T/C cg24425628 chr17:29625626 OMG;NF1 0.47 7.45 0.56 1.37e-11 Hip circumference; TGCT cis rs7953249 0.791 rs10774579 chr12:121405210 T/C cg00044289 chr12:121019603 POP5 -0.4 -4.44 -0.37 1.97e-5 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs12497850 0.931 rs9846123 chr3:49088112 C/T cg06212747 chr3:49208901 KLHDC8B -0.61 -5.66 -0.45 9.84e-8 Parkinson's disease; TGCT cis rs9325144 0.678 rs7315271 chr12:39164731 A/G cg13010199 chr12:38710504 ALG10B -0.52 -4.58 -0.38 1.12e-5 Morning vs. evening chronotype; TGCT cis rs611744 0.934 rs2848619 chr8:109198185 T/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs9486715 0.867 rs4839834 chr6:96882109 C/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs4919044 0.808 rs1238178 chr10:94804043 G/A cg05127821 chr10:94822908 CYP26C1 -0.75 -4.85 -0.4 3.67e-6 Coronary artery disease; TGCT cis rs7607369 0.648 rs17470271 chr2:219651995 A/T cg02176678 chr2:219576539 TTLL4 0.46 6.07 0.48 1.43e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs79149102 0.579 rs58068887 chr15:75286140 G/A cg09165964 chr15:75287851 SCAMP5 -1.07 -5.89 -0.47 3.42e-8 Lung cancer; TGCT cis rs6121246 0.609 rs6089054 chr20:30323141 A/G cg13852791 chr20:30311386 BCL2L1 0.84 8.15 0.59 3.38e-13 Mean corpuscular hemoglobin; TGCT cis rs7568458 0.684 rs1048740 chr2:85764966 A/T cg02493740 chr2:85810744 VAMP5 -0.28 -5.26 -0.43 6.1e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4820539 1.000 rs4822360 chr22:23482460 A/G cg14186256 chr22:23484241 RTDR1 0.99 12.69 0.75 3.59e-24 Bone mineral density; TGCT cis rs10504229 0.683 rs34859456 chr8:58117722 A/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs6845621 0.901 rs1452554 chr4:18920164 A/G cg12196642 chr4:18937545 NA 0.25 4.48 0.37 1.7e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs7617773 0.780 rs34523942 chr3:48342669 C/T cg11946769 chr3:48343235 NME6 0.81 7.01 0.53 1.35e-10 Coronary artery disease; TGCT cis rs4689388 0.581 rs4476672 chr4:6281496 A/G cg14416269 chr4:6271139 WFS1 0.47 5.6 0.45 1.32e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9894429 1.000 rs11651264 chr17:79576394 A/G cg21028142 chr17:79581711 NPLOC4 -0.29 -6.81 -0.52 3.83e-10 Eye color traits; TGCT cis rs9993613 0.778 rs7689931 chr4:73423124 C/T cg15102770 chr4:73434591 ADAMTS3 -0.5 -4.65 -0.39 8.51e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg11890956 chr21:40555474 PSMG1 1.04 11.03 0.7 3.96e-20 Cognitive function; TGCT trans rs1814175 0.645 rs11040661 chr11:49952146 G/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.49 -0.69 7.94e-19 Height; TGCT cis rs3091242 0.900 rs35345536 chr1:25766488 A/G cg23205692 chr1:25664452 TMEM50A 0.47 4.87 0.4 3.27e-6 Erythrocyte sedimentation rate; TGCT cis rs12477438 0.765 rs7591794 chr2:99567514 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.83 -8.29 -0.6 1.56e-13 Chronic sinus infection; TGCT cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg03264133 chr6:25882463 NA 0.74 7.71 0.57 3.43e-12 Blood metabolite levels; TGCT cis rs6490294 0.500 rs4767284 chr12:112440731 G/A cg10833066 chr12:111807467 FAM109A 0.34 5.32 0.43 4.69e-7 Mean platelet volume; TGCT cis rs10088262 0.629 rs12549683 chr8:124798276 G/C cg02993010 chr8:124780839 FAM91A1 -0.63 -5.13 -0.42 1.08e-6 Pancreatic cancer; TGCT cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2295359 1.000 rs4655684 chr1:67611772 A/G cg12940439 chr1:67600707 NA -0.58 -6.01 -0.47 1.95e-8 Psoriasis; TGCT cis rs6725041 0.792 rs1533769 chr2:213089956 A/C cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs17102423 0.755 rs942627 chr14:65550025 A/G cg11161011 chr14:65562177 MAX -0.55 -7.7 -0.57 3.74e-12 Obesity-related traits; TGCT cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg07636037 chr3:49044803 WDR6 0.88 9.05 0.63 2.49e-15 Menarche (age at onset); TGCT trans rs208520 0.754 rs1100989 chr6:66880532 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.31 -0.68 2.29e-18 Exhaled nitric oxide output; TGCT cis rs11671005 0.693 rs11668821 chr19:58955813 G/A cg07777224 chr19:58919807 ZNF584 -0.63 -4.47 -0.37 1.77e-5 Mean platelet volume; TGCT cis rs9733 0.596 rs72702536 chr1:150662574 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.56 0.38 1.23e-5 Tonsillectomy; TGCT cis rs9436747 0.714 rs1186403 chr1:66000533 C/T cg14976592 chr1:65886160 LEPROT;LEPR -0.49 -4.54 -0.38 1.32e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs12477438 0.798 rs6542849 chr2:99578493 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs854765 0.547 rs7223696 chr17:17915791 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.41 0.6 8.09e-14 Total body bone mineral density; TGCT cis rs7677751 0.943 rs9991165 chr4:55124591 A/G cg17187183 chr4:55093834 PDGFRA 0.5 5.18 0.42 8.8e-7 Corneal astigmatism; TGCT cis rs778371 0.522 rs10205801 chr2:233597196 G/A cg08000102 chr2:233561755 GIGYF2 0.61 6.92 0.53 2.12e-10 Schizophrenia; TGCT cis rs9611565 0.921 rs5751077 chr22:41720728 G/C cg03806693 chr22:41940476 POLR3H -0.86 -9.19 -0.64 1.16e-15 Vitiligo; TGCT cis rs782590 1.000 rs782594 chr2:55844445 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.88 0.53 2.6e-10 Metabolic syndrome; TGCT cis rs6121246 0.697 rs6087716 chr20:30229040 C/T cg13852791 chr20:30311386 BCL2L1 0.74 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin; TGCT cis rs2069837 0.515 rs12535219 chr7:22806159 C/G cg00365470 chr7:22893924 NA -0.64 -4.71 -0.39 6.64e-6 Longevity; TGCT cis rs12477438 0.520 rs4340581 chr2:99725025 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.26 0.77 1.59e-25 Chronic sinus infection; TGCT cis rs28595532 0.920 rs113034745 chr4:119750044 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs3125734 0.633 rs4979754 chr10:64048959 G/A cg19640130 chr10:64028056 RTKN2 -0.38 -4.79 -0.39 4.75e-6 Rheumatoid arthritis; TGCT cis rs9534288 0.797 rs7996875 chr13:46612836 C/T cg15192986 chr13:46630673 CPB2 0.5 6.97 0.53 1.7e-10 Blood protein levels; TGCT cis rs7681440 0.835 rs6831847 chr4:90785341 A/G cg20003494 chr4:90757398 SNCA 0.59 5.55 0.45 1.64e-7 Dementia with Lewy bodies; TGCT cis rs9814567 1.000 rs9841212 chr3:134191938 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.38 -0.64 3.97e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs12908161 0.959 rs35557864 chr15:85331629 A/G cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.1e-8 Schizophrenia; TGCT cis rs2180341 0.618 rs11154398 chr6:127654281 C/A cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs9914988 0.943 rs7215310 chr17:27088626 G/T cg20469991 chr17:27169893 C17orf63 -0.69 -5.04 -0.41 1.61e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2243480 1.000 rs316315 chr7:65591205 C/T cg20637647 chr7:64974828 NA -0.77 -4.78 -0.39 4.87e-6 Diabetic kidney disease; TGCT cis rs587847 0.558 rs619235 chr15:37664924 A/G cg16890051 chr15:37175029 LOC145845 -0.38 -4.49 -0.37 1.6e-5 Intraocular pressure; TGCT cis rs597539 0.652 rs592697 chr11:68650064 G/A cg21862992 chr11:68658383 NA 0.47 6.54 0.51 1.42e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13256369 0.950 rs12548792 chr8:8568031 T/C cg06671706 chr8:8559999 CLDN23 0.34 4.57 0.38 1.18e-5 Obesity-related traits; TGCT cis rs7731657 0.537 rs10076495 chr5:130362953 A/C cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs10791097 0.506 rs10750446 chr11:130706918 T/C cg12179176 chr11:130786555 SNX19 -0.48 -4.76 -0.39 5.2e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1448094 0.511 rs59858864 chr12:86166404 G/A cg02569458 chr12:86230093 RASSF9 0.38 4.5 0.37 1.57e-5 Major depressive disorder; TGCT cis rs7914558 0.966 rs4532960 chr10:104667406 C/T cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9611565 0.592 rs57102627 chr22:41987627 T/C cg17554472 chr22:41940697 POLR3H -0.49 -5.15 -0.42 9.88e-7 Vitiligo; TGCT cis rs981844 0.775 rs17299561 chr4:154765480 C/T cg14289246 chr4:154710475 SFRP2 0.95 8.45 0.6 6.67e-14 Response to statins (LDL cholesterol change); TGCT cis rs514406 0.861 rs6588443 chr1:53250650 G/A cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs6089829 0.962 rs4586690 chr20:61658595 G/T cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs1801251 1.000 rs1022330 chr2:233577330 G/A cg25237894 chr2:233734115 C2orf82 0.31 5.45 0.44 2.63e-7 Coronary artery disease; TGCT cis rs6429082 0.585 rs7524848 chr1:235711688 G/C cg26050004 chr1:235667680 B3GALNT2 -0.56 -4.9 -0.4 2.98e-6 Adiposity; TGCT cis rs916888 0.821 rs199512 chr17:44857352 T/C cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7043114 0.525 rs7847929 chr9:95154244 C/T cg14311495 chr9:95764742 FGD3 -0.22 -4.52 -0.38 1.41e-5 Height; TGCT cis rs6684514 0.961 rs12048077 chr1:156299916 T/A cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7246657 0.722 rs2972437 chr19:38210511 G/T cg03611452 chr19:38183253 ZNF781 0.56 4.63 0.38 8.97e-6 Coronary artery calcification; TGCT cis rs11190604 1.000 rs7100386 chr10:102301417 C/T cg23241863 chr10:102295624 HIF1AN 0.69 5.1 0.42 1.26e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2836974 0.932 rs11910151 chr21:40560262 T/C cg06238570 chr21:40685208 BRWD1 0.72 6.84 0.52 3.16e-10 Cognitive function; TGCT cis rs9291683 0.609 rs12500810 chr4:10031068 G/A cg11266682 chr4:10021025 SLC2A9 0.63 8.67 0.61 2.04e-14 Bone mineral density; TGCT cis rs4663866 1.000 rs6741269 chr2:239179418 A/G cg17283117 chr2:239148619 HES6 0.98 4.52 0.38 1.42e-5 Irritable bowel syndrome; TGCT cis rs1775715 0.737 rs2799015 chr10:32107712 C/T cg14930904 chr10:32216787 ARHGAP12 0.5 4.85 0.4 3.62e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2153535 0.547 rs9505475 chr6:8542890 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.63 0.45 1.14e-7 Motion sickness; TGCT cis rs1933488 0.931 rs3870364 chr6:153426679 G/A cg24028809 chr6:153414101 RGS17 0.21 4.69 0.39 7.12e-6 Prostate cancer; TGCT cis rs4664308 0.967 rs17241973 chr2:160918601 A/G cg03641300 chr2:160917029 PLA2R1 -0.27 -6.66 -0.51 7.81e-10 Idiopathic membranous nephropathy; TGCT cis rs7726839 0.794 rs10053310 chr5:595661 C/G cg09021430 chr5:549028 NA -0.41 -5.83 -0.46 4.48e-8 Obesity-related traits; TGCT cis rs7552404 0.731 rs1770887 chr1:76401812 A/G cg10523679 chr1:76189770 ACADM -0.85 -7.88 -0.58 1.42e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7647973 0.626 rs7637711 chr3:49829653 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.75 -0.39 5.61e-6 Menarche (age at onset); TGCT trans rs2749592 0.550 rs9733309 chr10:37882405 G/A cg17830980 chr10:43048298 ZNF37B 0.65 6.85 0.52 2.99e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9527 0.590 rs10786738 chr10:104869451 C/T cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs2836974 0.549 rs34160989 chr21:40554118 C/G cg17971929 chr21:40555470 PSMG1 0.68 4.67 0.39 7.78e-6 Cognitive function; TGCT cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg26531700 chr6:26746687 NA 0.54 5.28 0.43 5.71e-7 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 15.74 0.82 2.39e-31 Prudent dietary pattern; TGCT cis rs4906332 1.000 rs8004501 chr14:103981662 G/A cg26031613 chr14:104095156 KLC1 -0.54 -4.67 -0.39 7.66e-6 Coronary artery disease; TGCT cis rs3733585 0.664 rs17245436 chr4:9958169 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.68 -0.51 7.16e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1018836 0.608 rs1033347 chr8:91464137 G/A cg16814680 chr8:91681699 NA -0.77 -7.8 -0.57 2.21e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg11494091 chr17:61959527 GH2 0.6 14.36 0.79 3.83e-28 Prudent dietary pattern; TGCT cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Vitiligo; TGCT cis rs1538970 0.962 rs2185549 chr1:45814103 C/T cg05343316 chr1:45956843 TESK2 -0.67 -5.02 -0.41 1.77e-6 Platelet count; TGCT cis rs7659604 0.539 rs7686084 chr4:122764725 A/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.3 -0.43 5.06e-7 Type 2 diabetes; TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg03760483 chr17:6899297 ALOX12 -0.46 -5.22 -0.42 7.34e-7 Tonsillectomy; TGCT cis rs769267 1.000 rs7246748 chr19:19433105 C/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg08125733 chr17:73851984 WBP2 1.09 12.95 0.76 8.9e-25 Psoriasis; TGCT cis rs7727544 0.716 rs7720230 chr5:131592405 T/G cg22598563 chr5:131563921 P4HA2 -0.29 -4.67 -0.39 7.72e-6 Blood metabolite levels; TGCT cis rs2224391 0.628 rs2753244 chr6:5257610 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.14 -0.48 1.01e-8 Height; TGCT cis rs2839186 0.934 rs17176520 chr21:47682081 T/C cg13732083 chr21:47605072 C21orf56 0.35 4.5 0.37 1.55e-5 Testicular germ cell tumor; TGCT cis rs3821902 0.646 rs17344653 chr3:64015989 C/T cg22134162 chr3:63841271 THOC7 -0.32 -4.85 -0.4 3.7e-6 Breast cancer; TGCT cis rs9311474 0.713 rs181274 chr3:52233861 T/A cg07507251 chr3:52567010 NT5DC2 0.39 5.12 0.42 1.14e-6 Electroencephalogram traits; TGCT cis rs2153535 0.580 rs7763190 chr6:8484197 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs290268 0.874 rs290997 chr9:93559351 G/A cg02608019 chr9:93564028 SYK 0.46 4.65 0.39 8.23e-6 Platelet count; TGCT cis rs3892630 0.824 rs7247264 chr19:33239846 T/G cg22980127 chr19:33182716 NUDT19 0.7 5.07 0.41 1.44e-6 Red blood cell traits; TGCT cis rs919433 0.617 rs4850809 chr2:198583403 C/T cg00792783 chr2:198669748 PLCL1 -0.54 -4.96 -0.41 2.25e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs7829975 0.606 rs7833171 chr8:8699761 C/T cg08975724 chr8:8085496 FLJ10661 0.55 4.86 0.4 3.5e-6 Mood instability; TGCT cis rs4072705 0.967 rs4836986 chr9:127408059 C/T cg13476313 chr9:127244764 NR5A1 0.28 4.62 0.38 9.66e-6 Menarche (age at onset); TGCT cis rs1891498 0.602 rs10900396 chr1:147242596 C/T cg17941330 chr1:147245494 GJA5 0.33 4.51 0.38 1.48e-5 Cognitive performance; TGCT cis rs78487399 0.908 rs10186441 chr2:43840048 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.67 4.8 0.4 4.52e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11969893 0.850 rs9404058 chr6:101323078 T/C cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs763014 0.932 rs35067229 chr16:649638 T/C cg09263875 chr16:632152 PIGQ 0.31 6.88 0.53 2.65e-10 Height; TGCT cis rs10751667 0.961 rs7395928 chr11:952605 T/G cg06064525 chr11:970664 AP2A2 -0.33 -6.49 -0.5 1.83e-9 Alzheimer's disease (late onset); TGCT cis rs7267979 0.899 rs2179459 chr20:25456141 C/A cg14121845 chr20:25566513 NINL 0.46 5.05 0.41 1.56e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg16049864 chr8:95962084 TP53INP1 -0.63 -7.75 -0.57 2.82e-12 Type 2 diabetes; TGCT cis rs9894429 0.646 rs8080391 chr17:79566319 A/T cg21028142 chr17:79581711 NPLOC4 -0.3 -7.03 -0.53 1.2e-10 Eye color traits; TGCT cis rs11148252 0.595 rs9526968 chr13:53240183 T/C cg00495681 chr13:53174319 NA 0.62 6.27 0.49 5.35e-9 Lewy body disease; TGCT cis rs9677476 0.516 rs10199752 chr2:231969554 A/C cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs7296418 0.961 rs1790121 chr12:123604492 G/A cg13010344 chr12:123464640 ARL6IP4 -0.31 -4.44 -0.37 2e-5 Platelet count; TGCT cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg15691649 chr6:25882328 NA -0.41 -4.71 -0.39 6.41e-6 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.851 rs7275870 chr21:46671214 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2204008 0.774 rs11514062 chr12:38332297 A/C cg26384229 chr12:38710491 ALG10B 0.76 6.89 0.53 2.46e-10 Bladder cancer; TGCT cis rs11249608 0.548 rs62393074 chr5:178450476 G/C cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg20007245 chr22:24372913 LOC391322 -0.71 -7.04 -0.53 1.16e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7178572 0.889 rs869301 chr15:77830633 T/C cg22256960 chr15:77711686 NA -0.95 -10.69 -0.69 2.58e-19 Type 2 diabetes; TGCT cis rs6496667 0.642 rs12148876 chr15:91065208 G/A cg22089800 chr15:90895588 ZNF774 0.64 4.46 0.37 1.81e-5 Rheumatoid arthritis; TGCT cis rs7909074 1.000 rs4948926 chr10:45392604 G/C cg05187965 chr10:45406764 TMEM72 -0.25 -5.34 -0.43 4.2e-7 Mean corpuscular volume; TGCT cis rs3027009 0.881 rs56184975 chr1:159149253 G/T cg11719576 chr1:158153771 CD1D -0.39 -4.52 -0.38 1.41e-5 Lean body mass and age at menarche (combined); TGCT cis rs7772486 0.875 rs10457793 chr6:146415403 A/G cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.546 rs132793 chr22:42063681 A/G cg06634786 chr22:41940651 POLR3H 0.87 8.3 0.6 1.49e-13 Vitiligo; TGCT cis rs7772486 0.754 rs4360151 chr6:146255079 A/C cg23711669 chr6:146136114 FBXO30 -0.85 -9.7 -0.66 6.73e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7020830 0.516 rs36047049 chr9:37375472 G/T cg14294708 chr9:37120828 ZCCHC7 0.97 9.42 0.65 3.14e-16 Schizophrenia; TGCT cis rs4455778 0.580 rs4304291 chr7:49116983 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs1218582 0.741 rs10908447 chr1:154869742 C/T cg09359103 chr1:154839909 KCNN3 -0.71 -15.31 -0.81 2.37e-30 Prostate cancer; TGCT cis rs3820928 0.904 rs2195487 chr2:227759720 G/C cg11843606 chr2:227700838 RHBDD1 -0.58 -5.15 -0.42 9.93e-7 Pulmonary function; TGCT cis rs2075371 0.933 rs2244548 chr7:133986234 A/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs950169 1.000 rs1911155 chr15:84787635 A/G cg12863693 chr15:85201151 NMB 0.39 4.65 0.38 8.54e-6 Schizophrenia; TGCT cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg11062466 chr8:58055876 NA 0.38 4.5 0.37 1.56e-5 Developmental language disorder (linguistic errors); TGCT cis rs9921338 0.961 rs8056282 chr16:11407236 T/C cg00044050 chr16:11439710 C16orf75 -0.93 -6.89 -0.53 2.5e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs875971 0.964 rs6978721 chr7:65883204 A/G cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs4713675 0.624 rs482786 chr6:33707599 T/C cg18005901 chr6:33739558 LEMD2 0.54 6.37 0.5 3.33e-9 Plateletcrit; TGCT cis rs2594989 0.943 rs7646500 chr3:11478000 A/G cg00170343 chr3:11313890 ATG7 0.67 5.12 0.42 1.13e-6 Circulating chemerin levels; TGCT cis rs778371 1.000 rs778370 chr2:233743363 C/T cg08000102 chr2:233561755 GIGYF2 -0.59 -6.56 -0.51 1.29e-9 Schizophrenia; TGCT cis rs1218582 0.741 rs2335407 chr1:154843347 A/G cg06221963 chr1:154839813 KCNN3 0.82 15.81 0.82 1.62e-31 Prostate cancer; TGCT cis rs9308731 0.623 rs6708784 chr2:111927379 A/G cg04202892 chr2:111875749 ACOXL 0.55 6.42 0.5 2.64e-9 Chronic lymphocytic leukemia; TGCT cis rs6754311 0.589 rs2011724 chr2:136818006 A/G cg07169764 chr2:136633963 MCM6 -0.56 -5.48 -0.44 2.29e-7 Mosquito bite size; TGCT cis rs896854 0.517 rs1011796 chr8:95951273 A/G cg13393036 chr8:95962371 TP53INP1 0.5 5.8 0.46 5.2100000000000003e-08 Type 2 diabetes; TGCT cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9467711 0.606 rs9379875 chr6:26444732 C/T cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs319204 0.918 rs2963080 chr5:146261089 C/T cg13983063 chr5:146258615 PPP2R2B 0.32 4.59 0.38 1.06e-5 Schizophrenia; TGCT cis rs11098499 0.863 rs3822195 chr4:120471660 C/T cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 -0.51 -5.81 -0.46 4.97e-8 Lymphocyte counts; TGCT cis rs7267979 1.000 rs2424710 chr20:25283886 C/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6500596 0.506 rs1530088 chr16:4439131 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 4.61 0.38 9.75e-6 Schizophrenia; TGCT cis rs2204008 0.837 rs4432085 chr12:38181146 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT cis rs7224685 0.569 rs67533014 chr17:3993910 C/T cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs1475911 1.000 rs2839467 chr21:43513200 A/G cg14562523 chr21:43528734 C21orf128;UMODL1 0.25 4.95 0.41 2.35e-6 IgG glycosylation; TGCT cis rs6952809 0.516 rs6952959 chr7:2440722 C/T cg23289794 chr7:2394357 EIF3B -0.84 -7.21 -0.54 4.72e-11 Multiple sclerosis; TGCT cis rs2637266 0.703 rs7920374 chr10:78455861 T/C cg18941641 chr10:78392320 NA 0.41 4.9 0.4 2.95e-6 Pulmonary function; TGCT cis rs11864453 0.647 rs3764314 chr16:72127078 T/C cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs873946 0.586 rs3793685 chr10:134569316 G/A cg26818010 chr10:134567672 INPP5A -0.38 -5.19 -0.42 8.5e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9583531 0.629 rs7991766 chr13:111380684 A/G cg24331049 chr13:111365604 ING1 0.85 8.25 0.6 1.97e-13 Coronary artery disease; TGCT cis rs796364 0.616 rs6710393 chr2:200697246 G/A cg17644776 chr2:200775616 C2orf69 0.35 4.99 0.41 1.97e-6 Schizophrenia; TGCT cis rs7937682 0.883 rs1611989 chr11:111456299 A/G cg09085632 chr11:111637200 PPP2R1B -0.97 -9.75 -0.66 5.24e-17 Primary sclerosing cholangitis; TGCT cis rs950169 0.922 rs12915832 chr15:85111457 C/T cg11189052 chr15:85197271 WDR73 0.77 6.42 0.5 2.68e-9 Schizophrenia; TGCT trans rs9567307 1 rs9567307 chr13:44471877 A/G cg12856521 chr11:46389249 DGKZ 0.66 7.29 0.55 3.14e-11 Leprosy; TGCT cis rs1670533 1.000 rs629261 chr4:1086763 A/C cg20887711 chr4:1340912 KIAA1530 0.66 5.33 0.43 4.49e-7 Recombination rate (females); TGCT cis rs28595532 0.920 rs73842253 chr4:119721856 G/A cg21605333 chr4:119757512 SEC24D 1.53 7.83 0.58 1.83e-12 Cannabis dependence symptom count; TGCT cis rs11971779 0.752 rs4732371 chr7:139077317 T/A cg07862535 chr7:139043722 LUC7L2 0.72 5.61 0.45 1.24e-7 Diisocyanate-induced asthma; TGCT cis rs46522 0.585 rs79049364 chr17:47014991 T/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.5 -0.37 1.53e-5 Coronary heart disease; TGCT cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg22168489 chr12:122356033 WDR66 0.2 4.74 0.39 5.87e-6 Mean corpuscular volume; TGCT cis rs751728 0.965 rs4713681 chr6:33754817 T/C cg13859433 chr6:33739653 LEMD2 -0.4 -7.16 -0.54 6.32e-11 Crohn's disease; TGCT cis rs151997 0.925 rs26090 chr5:50170071 C/T cg06027927 chr5:50259733 NA -0.45 -4.59 -0.38 1.08e-5 Callous-unemotional behaviour; TGCT cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg07061783 chr6:25882402 NA -0.43 -4.76 -0.39 5.23e-6 Height; TGCT cis rs17221829 0.645 rs4002142 chr11:89374013 G/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs7666738 0.830 rs9995370 chr4:98732145 T/G cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2885056 0.830 rs2018810 chr19:10669172 A/G cg04833646 chr19:10679720 CDKN2D 0.95 9.16 0.64 1.36e-15 Red cell distribution width; TGCT cis rs8070740 0.617 rs1058117 chr17:5323206 T/G cg25236894 chr17:5323110 RPAIN;NUP88 0.64 6.3 0.49 4.68e-9 Menopause (age at onset); TGCT cis rs2777491 0.574 rs316611 chr15:41751678 A/G cg18705301 chr15:41695430 NDUFAF1 0.95 16.29 0.83 1.36e-32 Ulcerative colitis; TGCT cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs4705962 0.878 rs2023823 chr5:132032806 A/G cg13566430 chr5:131992455 IL13 -0.28 -4.44 -0.37 1.97e-5 Atopic dermatitis; TGCT cis rs9326248 0.954 rs8521 chr11:117067699 C/T cg11861562 chr11:117069780 TAGLN 0.27 4.46 0.37 1.78e-5 Blood protein levels; TGCT cis rs7043114 0.525 rs7869742 chr9:95256174 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.41 -0.44 3.1e-7 Height; TGCT cis rs10984561 0.881 rs80242897 chr9:122248625 A/G cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs7809950 1.000 rs4727680 chr7:107087407 T/G cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT cis rs2227564 0.620 rs11000765 chr10:75512452 G/C cg19442545 chr10:75533431 FUT11 -0.31 -4.55 -0.38 1.26e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4654899 0.802 rs10916906 chr1:21255675 C/A cg01072550 chr1:21505969 NA -0.47 -7.02 -0.53 1.3100000000000001e-10 Superior frontal gyrus grey matter volume; TGCT cis rs911186 0.786 rs3800307 chr6:27185792 A/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.55 -4.81 -0.4 4.35e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9326248 1.000 rs4938354 chr11:117051165 A/G cg16524733 chr11:117070046 TAGLN 0.32 4.54 0.38 1.3e-5 Blood protein levels; TGCT cis rs1150668 0.835 rs203869 chr6:28040819 T/A cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.67 -0.39 7.63e-6 Pubertal anthropometrics; TGCT cis rs9926296 0.656 rs2376884 chr16:89826922 C/T cg08627397 chr16:89984028 MC1R -0.29 -4.55 -0.38 1.26e-5 Vitiligo; TGCT cis rs2242116 0.896 rs724448 chr3:46935734 A/C cg27129171 chr3:47204927 SETD2 0.61 6.15 0.48 9.79e-9 Birth weight; TGCT cis rs7829975 0.600 rs1719381 chr8:8602344 T/C cg06636001 chr8:8085503 FLJ10661 -0.58 -4.79 -0.39 4.72e-6 Mood instability; TGCT cis rs16854884 0.690 rs35885310 chr3:143771333 A/G cg06585982 chr3:143692056 C3orf58 0.64 5.17 0.42 9.12e-7 Economic and political preferences (feminism/equality); TGCT cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7917772 0.636 rs2482499 chr10:104516246 G/A cg05855489 chr10:104503620 C10orf26 -0.65 -5.17 -0.42 9.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.75 -0.39 5.44e-6 Prudent dietary pattern; TGCT cis rs2486012 1.000 rs1766966 chr1:44382515 A/G cg12908607 chr1:44402522 ARTN 0.68 5.76 0.46 6.14e-8 Intelligence (multi-trait analysis); TGCT cis rs854765 0.583 rs8070722 chr17:17813562 C/T cg09796270 chr17:17721594 SREBF1 0.24 4.72 0.39 6.36e-6 Total body bone mineral density; TGCT cis rs4253772 0.591 rs9615934 chr22:46682310 C/G cg24881330 chr22:46731750 TRMU 1.02 5.07 0.41 1.4e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs7647973 0.922 rs6809851 chr3:49309787 C/A cg06212747 chr3:49208901 KLHDC8B 0.56 4.46 0.37 1.78e-5 Menarche (age at onset); TGCT cis rs7666738 0.830 rs1559859 chr4:99024325 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg07157834 chr1:205819609 PM20D1 0.36 5.55 0.45 1.63e-7 Monocyte percentage of white cells; TGCT cis rs8013055 0.796 rs4075104 chr14:106000214 C/A cg19700328 chr14:106028568 NA -0.46 -5.14 -0.42 1.05e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9291683 0.526 rs12506122 chr4:10033538 C/A cg11266682 chr4:10021025 SLC2A9 0.61 7.76 0.57 2.67e-12 Bone mineral density; TGCT cis rs3008870 0.958 rs12143044 chr1:67460054 A/T cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs7927997 0.757 rs2212434 chr11:76281593 C/T cg17647271 chr11:76299819 NA 0.54 6.47 0.5 2.01e-9 Gut microbiota (functional units);Crohn's disease; TGCT cis rs12220238 1.000 rs12358614 chr10:75906173 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7020830 0.898 rs7038219 chr9:37182892 C/A cg14294708 chr9:37120828 ZCCHC7 1.17 16.15 0.82 2.76e-32 Schizophrenia; TGCT cis rs3733631 0.895 rs28592258 chr4:104621036 C/A cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT cis rs6460942 1.000 rs6944134 chr7:12418036 T/C cg06484146 chr7:12443880 VWDE -0.59 -5.6 -0.45 1.28e-7 Coronary artery disease; TGCT cis rs6952809 0.561 rs1548598 chr7:2438912 T/C cg23289794 chr7:2394357 EIF3B -0.84 -7.17 -0.54 5.84e-11 Multiple sclerosis; TGCT cis rs10507380 0.824 rs9512641 chr13:27922574 C/T cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs7291412 0.600 rs7511013 chr22:46447132 C/G cg05468064 chr22:46423449 NA 0.51 4.64 0.38 8.68e-6 Dupuytren's disease;Subjective well-being; TGCT cis rs782590 0.537 rs7575170 chr2:55886780 C/T cg18811423 chr2:55921094 PNPT1 -0.63 -5.34 -0.43 4.26e-7 Metabolic syndrome; TGCT cis rs10838634 1.000 rs7102474 chr11:46833092 T/C cg18332754 chr11:46939436 LRP4 0.89 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.53 4.72 0.39 6.34e-6 Prudent dietary pattern; TGCT cis rs2153535 0.580 rs962590 chr6:8450899 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs7584330 0.737 rs1390985 chr2:238367420 G/A cg14458575 chr2:238380390 NA 0.51 8.25 0.6 1.91e-13 Prostate cancer; TGCT trans rs2832077 0.527 rs9981922 chr21:30212718 A/G cg14791747 chr16:20752902 THUMPD1 1.07 12.57 0.75 7.04e-24 Cognitive test performance; TGCT cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg11062466 chr8:58055876 NA 0.43 4.52 0.38 1.45e-5 Developmental language disorder (linguistic errors); TGCT cis rs2235642 0.785 rs1057983 chr16:1660274 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.28 -4.96 -0.41 2.28e-6 Coronary artery disease; TGCT cis rs6964587 0.935 rs9770444 chr7:91783162 T/G cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.33e-6 Breast cancer; TGCT cis rs7119 0.667 rs1058129 chr15:77905661 A/G cg27398640 chr15:77910606 LINGO1 0.31 6.62 0.51 9.78e-10 Type 2 diabetes; TGCT cis rs2692947 0.726 rs13019188 chr2:96774199 A/G cg05933789 chr2:97190408 NA -0.15 -4.53 -0.38 1.35e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4713118 0.513 rs149951 chr6:28033087 T/C cg10876282 chr6:28092338 ZSCAN16 0.5 4.6 0.38 1.01e-5 Parkinson's disease; TGCT cis rs12681288 0.748 rs2123054 chr8:1028227 C/G cg04851639 chr8:1020857 NA -0.34 -6.11 -0.48 1.18e-8 Schizophrenia; TGCT cis rs60871478 0.636 rs12534606 chr7:895928 A/G cg15782153 chr7:917662 C7orf20 0.54 4.92 0.4 2.74e-6 Cerebrospinal P-tau181p levels; TGCT cis rs4478858 0.684 rs2050816 chr1:31721708 G/T cg00250761 chr1:31883323 NA -0.27 -4.79 -0.4 4.59e-6 Alcohol dependence; TGCT cis rs3820928 0.605 rs4675124 chr2:227802354 G/A cg11843606 chr2:227700838 RHBDD1 -0.51 -4.82 -0.4 4.1e-6 Pulmonary function; TGCT cis rs2997447 0.761 rs61776596 chr1:26454968 T/C cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs5769765 0.908 rs4824109 chr22:50271460 T/C cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs2204008 0.729 rs2892365 chr12:38446760 G/C cg26384229 chr12:38710491 ALG10B -0.8 -7.45 -0.56 1.42e-11 Bladder cancer; TGCT cis rs11098499 0.863 rs34308924 chr4:120481431 T/C cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs875971 0.660 rs801217 chr7:66010577 C/T cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs9303401 0.659 rs12946397 chr17:56769979 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs4499344 0.622 rs73573371 chr19:33047095 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.7 -6.14 -0.48 1.01e-8 Mean platelet volume; TGCT cis rs586688 0.582 rs550365 chr1:201665278 A/G cg07139329 chr1:201708558 NAV1 -0.55 -5.47 -0.44 2.37e-7 Obesity-related traits; TGCT cis rs644799 0.687 rs3748252 chr11:95519195 A/T cg03916912 chr11:95522834 CEP57;FAM76B -0.81 -9.5 -0.65 2.06e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7659604 1.000 rs73844281 chr4:122664688 A/G cg19748678 chr4:122722346 EXOSC9 0.57 5.5 0.44 2.07e-7 Type 2 diabetes; TGCT cis rs763014 0.966 rs4984675 chr16:670117 T/C cg00908189 chr16:619842 PIGQ 0.87 10.61 0.69 4.21e-19 Height; TGCT cis rs7727544 0.618 rs2631367 chr5:131705458 C/G cg24060327 chr5:131705240 SLC22A5 0.52 5.38 0.44 3.55e-7 Blood metabolite levels; TGCT cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg07507251 chr3:52567010 NT5DC2 0.47 6.63 0.51 9.08e-10 Electroencephalogram traits; TGCT cis rs7772486 0.686 rs702314 chr6:146003510 G/A cg13319975 chr6:146136371 FBXO30 0.49 4.44 0.37 1.99e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6582630 0.502 rs11520261 chr12:38332019 T/G cg26384229 chr12:38710491 ALG10B 0.76 6.89 0.53 2.46e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs17102423 1.000 rs4902365 chr14:65602064 T/C cg11161011 chr14:65562177 MAX -0.48 -6.46 -0.5 2.18e-9 Obesity-related traits; TGCT cis rs7246657 0.722 rs1531549 chr19:38088009 T/C cg03611452 chr19:38183253 ZNF781 0.59 4.72 0.39 6.14e-6 Coronary artery calcification; TGCT cis rs4794202 0.629 rs59111282 chr17:45902414 G/T cg02219949 chr17:45927392 SP6 0.42 4.52 0.38 1.4e-5 Alzheimer's disease (cognitive decline); TGCT cis rs1008375 0.900 rs6812675 chr4:17597549 A/G cg18681998 chr4:17616180 MED28 0.87 7.67 0.57 4.29e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7909074 0.899 rs2026428 chr10:45389452 T/C cg04218760 chr10:45406644 TMEM72 -0.28 -5.66 -0.45 1.01e-7 Mean corpuscular volume; TGCT cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs2486012 0.737 rs6691988 chr1:44254402 A/G cg12908607 chr1:44402522 ARTN 0.59 5.17 0.42 9.14e-7 Intelligence (multi-trait analysis); TGCT cis rs950169 0.810 rs62029594 chr15:84955252 T/C cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs4631830 0.812 rs11593361 chr10:51539156 A/G cg10326726 chr10:51549505 MSMB -0.26 -5.29 -0.43 5.44e-7 Prostate-specific antigen levels; TGCT cis rs6586163 0.527 rs3824730 chr10:90752128 A/T cg03111039 chr10:90751583 FAS;ACTA2 0.6 7.77 0.57 2.59e-12 Chronic lymphocytic leukemia; TGCT cis rs7428 0.527 rs1061782 chr2:85546615 A/G cg24342717 chr2:85555507 TGOLN2 0.48 8.12 0.59 3.89e-13 Ear protrusion; TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg10263370 chr3:44754102 ZNF502 -0.47 -5.67 -0.45 9.54e-8 Depressive symptoms; TGCT cis rs4727027 0.933 rs34578816 chr7:148847606 G/A cg23583168 chr7:148888333 NA -0.76 -9.83 -0.66 3.29e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs138024639 1 rs138024639 chr6:28436014 TAAACATA/T cg10876282 chr6:28092338 ZSCAN16 0.86 4.46 0.37 1.8e-5 Breast cancer; TGCT cis rs17384381 0.861 rs12736004 chr1:85901367 G/A cg16011679 chr1:85725395 C1orf52 0.82 6.56 0.51 1.28e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs3749237 0.595 rs3870337 chr3:49557095 G/T cg03060546 chr3:49711283 APEH 0.75 8.62 0.61 2.66e-14 Resting heart rate; TGCT cis rs2439831 0.571 rs689883 chr15:43812596 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.97 7.38 0.55 1.96e-11 Lung cancer in ever smokers; TGCT cis rs7833790 1.000 rs7460277 chr8:82709777 T/C cg27398817 chr8:82754497 SNX16 -0.82 -5.86 -0.47 3.96e-8 Diastolic blood pressure; TGCT cis rs7267979 1.000 rs4815406 chr20:25341316 C/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg12310025 chr6:25882481 NA 0.51 4.62 0.38 9.56e-6 Intelligence (multi-trait analysis); TGCT cis rs10782582 0.593 rs6664254 chr1:76235084 G/T cg22875332 chr1:76189707 ACADM -0.45 -4.93 -0.4 2.55e-6 Daytime sleep phenotypes; TGCT cis rs1568889 1.000 rs7112860 chr11:28151609 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.68 0.61 1.88e-14 Bipolar disorder; TGCT trans rs1814175 0.669 rs11040473 chr11:49703813 C/T cg15704280 chr7:45808275 SEPT13 -0.6 -6.94 -0.53 1.92e-10 Height; TGCT cis rs10992471 0.603 rs12342019 chr9:95192508 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.94 -0.47 2.62e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7568458 0.870 rs1972297 chr2:85808573 T/C cg02493740 chr2:85810744 VAMP5 -0.26 -4.75 -0.39 5.51e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1497406 0.590 rs6676143 chr1:16528218 G/T cg20430773 chr1:16534157 ARHGEF19 0.48 5.55 0.45 1.68e-7 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7845219 0.525 rs3019175 chr8:95949013 G/A cg13393036 chr8:95962371 TP53INP1 -0.46 -5.28 -0.43 5.52e-7 Type 2 diabetes; TGCT cis rs3008870 0.755 rs2208577 chr1:67513574 A/C cg02640540 chr1:67518911 SLC35D1 0.65 5.88 0.47 3.62e-8 Lymphocyte percentage of white cells; TGCT cis rs9926296 0.605 rs12709094 chr16:89853017 A/G cg21285383 chr16:89894308 SPIRE2 0.46 7.19 0.54 5.44e-11 Vitiligo; TGCT cis rs11779988 0.516 rs426498 chr8:17897158 T/C cg01800426 chr8:17659068 MTUS1 -0.6 -4.63 -0.38 9.07e-6 Breast cancer; TGCT cis rs5769765 1.000 rs2295409 chr22:50261060 G/C cg22709217 chr22:50311962 ALG12;CRELD2 1.09 11.03 0.7 4e-20 Schizophrenia; TGCT cis rs765787 0.530 rs2899381 chr15:45529630 C/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.75e-7 Uric acid levels; TGCT cis rs73110464 0.505 rs2638503 chr12:53307369 C/G cg25025879 chr12:53359317 NA -0.37 -4.78 -0.39 4.78e-6 Cancer (pleiotropy); TGCT cis rs7945705 0.870 rs1109305 chr11:8955272 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.18 0.42 8.66e-7 Hemoglobin concentration; TGCT cis rs10193935 0.901 rs92303 chr2:42656337 A/G cg27598129 chr2:42591480 NA 0.33 4.97 0.41 2.13e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7681440 0.835 rs7656954 chr4:90784670 G/A cg20003494 chr4:90757398 SNCA -0.6 -5.54 -0.45 1.71e-7 Dementia with Lewy bodies; TGCT cis rs2180341 1.000 rs6937287 chr6:127645719 T/A cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs425277 1.000 rs421992 chr1:2077260 C/T cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs3780378 0.967 rs7043371 chr9:5040203 T/A cg02405213 chr9:5042618 JAK2 -0.59 -7.69 -0.57 3.87e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1570884 0.684 rs7326825 chr13:50113450 G/A cg08779649 chr13:50194554 NA 0.3 4.72 0.39 6.29e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs9473924 0.505 rs34793301 chr6:50859462 G/T cg14470998 chr6:50812995 TFAP2B 1.34 7.08 0.54 9.62e-11 Body mass index; TGCT cis rs9549367 0.713 rs3024745 chr13:113821598 A/G cg18105134 chr13:113819100 PROZ -0.46 -7.76 -0.57 2.75e-12 Platelet distribution width; TGCT cis rs1670533 1.000 rs2045068 chr4:1052212 G/A cg27284194 chr4:1044797 NA 0.7 5.88 0.47 3.62e-8 Recombination rate (females); TGCT cis rs2997447 0.761 rs17356867 chr1:26448849 C/T cg03844060 chr1:26490628 NA -0.28 -4.57 -0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs861020 0.677 rs2049998 chr1:210031154 C/T cg05527609 chr1:210001259 C1orf107 -0.95 -8.13 -0.59 3.74e-13 Orofacial clefts; TGCT cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.56 0.45 1.56e-7 Height; TGCT cis rs2180341 0.960 rs9398839 chr6:127665863 G/A cg27446573 chr6:127587934 RNF146 1.2 10.61 0.69 4.11e-19 Breast cancer; TGCT cis rs1903068 0.785 rs10013228 chr4:55997340 A/G cg01777861 chr4:56023843 NA 0.53 6.16 0.48 9.28e-9 Endometriosis; TGCT cis rs734999 0.588 rs4648562 chr1:2535613 C/A cg18854424 chr1:2615690 NA 0.43 4.96 0.41 2.31e-6 Ulcerative colitis; TGCT cis rs2066819 1.000 rs77120931 chr12:56646213 A/C cg26714650 chr12:56694279 CS -1.33 -6.24 -0.49 6.46e-9 Psoriasis vulgaris; TGCT cis rs12602172 1 rs12602172 chr17:38163567 G/A cg17467752 chr17:38218738 THRA 0.54 5.22 0.42 7.25e-7 Neutrophil percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg20203395 chr5:56204925 C5orf35 -0.57 -4.84 -0.4 3.85e-6 Initial pursuit acceleration; TGCT cis rs9952991 0.941 rs2014857 chr18:12774326 C/T cg23598886 chr18:12777645 NA 0.62 5.78 0.46 5.63e-8 Inflammatory skin disease; TGCT cis rs10791097 0.694 rs7942621 chr11:130751308 C/G cg05962950 chr11:130786565 SNX19 0.91 11.68 0.72 1.01e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs644799 0.965 rs607039 chr11:95547086 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7714584 1.000 rs11955172 chr5:150254378 T/C cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs875971 0.929 rs12673810 chr7:65923853 T/A cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs6543140 0.964 rs4851592 chr2:103087641 C/T cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs597539 0.652 rs602805 chr11:68662076 A/T cg21963583 chr11:68658836 MRPL21 0.36 6.01 0.47 1.94e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg10047753 chr17:41438598 NA 0.95 9.5 0.65 2.09e-16 Menopause (age at onset); TGCT cis rs113352275 1 rs113352275 chr15:78840567 C/T cg24631222 chr15:78858424 CHRNA5 0.93 7.58 0.56 7.12e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg02073558 chr3:44770973 ZNF501 0.69 6.94 0.53 1.92e-10 Depressive symptoms; TGCT cis rs4862750 0.872 rs7664463 chr4:187876686 A/C cg22105103 chr4:187893119 NA 0.35 4.94 0.41 2.49e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4819052 0.918 rs2330013 chr21:46658662 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.88 7.28 0.55 3.36e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7027203 0.828 rs7037960 chr9:96584028 G/A cg13679303 chr9:96623674 NA -0.66 -10.64 -0.69 3.54e-19 DNA methylation (variation); TGCT cis rs7027203 0.557 rs2487015 chr9:96521240 T/G cg13679303 chr9:96623674 NA -0.53 -7.48 -0.56 1.18e-11 DNA methylation (variation); TGCT cis rs4924935 0.851 rs17743944 chr17:18809268 A/G cg26378065 chr17:18585709 ZNF286B -0.56 -4.64 -0.38 8.86e-6 Pancreatic cancer; TGCT cis rs76878669 0.793 rs10791867 chr11:66081211 C/G cg18002602 chr11:66138449 SLC29A2 -0.53 -6.05 -0.48 1.62e-8 Educational attainment (years of education); TGCT cis rs6570726 0.791 rs379040 chr6:145889035 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs72949976 0.966 rs6752061 chr2:214027818 C/T cg08319019 chr2:214017104 IKZF2 -0.83 -7.74 -0.57 2.99e-12 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs67311347 0.577 rs1317217 chr3:40271697 T/G cg13683864 chr3:40499215 RPL14 -0.79 -7.58 -0.56 7.16e-12 Renal cell carcinoma; TGCT cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs7769051 0.522 rs7775241 chr6:133109022 T/C cg22852734 chr6:133119734 C6orf192 1.22 4.65 0.39 8.32e-6 Type 2 diabetes nephropathy; TGCT cis rs909002 0.849 rs10914456 chr1:32088171 T/C cg11573219 chr1:32083031 HCRTR1 -0.49 -6.39 -0.5 3.06e-9 Intelligence (multi-trait analysis); TGCT cis rs116161686 0.500 rs76610459 chr1:210050756 T/G cg21951975 chr1:209979733 IRF6 0.63 4.96 0.41 2.23e-6 Coronary artery disease; TGCT cis rs208515 0.525 rs4145045 chr6:66678949 T/C cg07460842 chr6:66804631 NA 0.87 9.16 0.64 1.32e-15 Exhaled nitric oxide levels; TGCT cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs2458413 0.903 rs2669448 chr8:105372324 T/G cg13045555 chr8:105342365 NA 0.34 5.04 0.41 1.6e-6 Paget's disease; TGCT cis rs36051895 0.659 rs57299248 chr9:5062932 C/G cg02405213 chr9:5042618 JAK2 -0.79 -11.54 -0.72 2.28e-21 Pediatric autoimmune diseases; TGCT cis rs35306767 0.668 rs12356612 chr10:1055055 C/T cg18964960 chr10:1102726 WDR37 0.75 5.48 0.44 2.23e-7 Eosinophil percentage of granulocytes; TGCT cis rs9928842 0.771 rs2870471 chr16:75274282 A/G cg09066997 chr16:75300724 BCAR1 -0.23 -4.44 -0.37 2e-5 Alcoholic chronic pancreatitis; TGCT cis rs9291683 0.588 rs11732054 chr4:9999877 C/T cg11266682 chr4:10021025 SLC2A9 0.66 9.23 0.64 9.39e-16 Bone mineral density; TGCT cis rs1050631 0.960 rs1789503 chr18:33696865 T/G cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.95 0.41 2.33e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs9473924 0.542 rs4294001 chr6:50850065 G/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs853679 0.517 rs868987 chr6:28110148 A/G cg12963246 chr6:28129442 ZNF389 -0.53 -5.09 -0.42 1.27e-6 Depression; TGCT cis rs61990749 0.597 rs176943 chr14:78175797 T/G cg02301378 chr14:78227641 SNW1;C14orf178 -0.6 -4.45 -0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs7542091 0.704 rs7537294 chr1:210043777 A/G cg22029157 chr1:209979665 IRF6 0.64 6.1 0.48 1.23e-8 Monobrow; TGCT cis rs3793917 0.901 rs36212732 chr10:124215198 A/G cg09507567 chr10:124027408 NA 0.4 4.89 0.4 3.12e-6 Age-related macular degeneration; TGCT cis rs3820068 0.580 rs36100011 chr1:16046920 C/T cg17385448 chr1:15911702 AGMAT 0.35 4.63 0.38 8.97e-6 Systolic blood pressure; TGCT cis rs3820928 0.874 rs11685983 chr2:227799853 A/G cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.9e-6 Pulmonary function; TGCT cis rs2455601 0.529 rs2653569 chr11:8986978 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -4.73 -0.39 6.02e-6 Schizophrenia; TGCT cis rs2637266 0.654 rs846576 chr10:78500388 T/A cg18941641 chr10:78392320 NA 0.42 5.03 0.41 1.7e-6 Pulmonary function; TGCT cis rs12477438 0.798 rs4850894 chr2:99629396 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs1371867 0.875 rs1788173 chr8:101330939 A/G cg06002616 chr8:101225028 SPAG1 0.53 6.34 0.49 3.9e-9 Atrioventricular conduction; TGCT cis rs7635838 0.859 rs6786166 chr3:11511424 T/C cg00170343 chr3:11313890 ATG7 0.65 5.97 0.47 2.33e-8 HDL cholesterol; TGCT cis rs12478296 0.792 rs6755390 chr2:243012998 C/T cg06360820 chr2:242988706 NA -0.64 -5.02 -0.41 1.73e-6 Obesity-related traits; TGCT cis rs1215050 0.791 rs6813619 chr4:98830768 C/T cg17366294 chr4:99064904 C4orf37 -0.55 -5.92 -0.47 2.97e-8 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs8073060 0.821 rs11080355 chr17:33872694 T/A cg19694781 chr19:47549865 TMEM160 0.43 7.9 0.58 1.27e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1008375 0.931 rs6449309 chr4:17573208 C/T cg10189774 chr4:17578691 LAP3 0.61 5.35 0.43 4.06e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs319204 0.959 rs525418 chr5:146285437 G/A cg25021259 chr5:146258546 PPP2R2B 0.35 4.51 0.38 1.5e-5 Schizophrenia; TGCT cis rs2404602 0.692 rs12910382 chr15:77053442 A/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs2594989 1.000 rs2594990 chr3:11317897 G/T cg00170343 chr3:11313890 ATG7 0.66 4.99 0.41 2.02e-6 Circulating chemerin levels; TGCT cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs8051431 0.876 rs4788452 chr16:72012847 C/A cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs7917772 0.502 rs2296583 chr10:104244322 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg03517284 chr6:25882590 NA 0.55 4.81 0.4 4.33e-6 Intelligence (multi-trait analysis); TGCT cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg27588902 chr6:42928151 GNMT -0.49 -5.94 -0.47 2.69e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4988958 0.565 rs1035125 chr2:103033839 C/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs6570726 0.846 rs9399559 chr6:145945778 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs8177253 0.965 rs7638018 chr3:133495461 C/T cg01448562 chr3:133502909 NA 0.34 7.06 0.54 1.07e-10 Iron status biomarkers; TGCT trans rs561341 0.941 rs72825736 chr17:30330286 G/A cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs9916302 0.904 rs801420 chr17:37466103 C/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT trans rs1814175 0.817 rs10769648 chr11:50013992 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs6840360 0.642 rs4696092 chr4:152412603 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs7953249 0.656 rs2178463 chr12:121389721 A/G cg02403541 chr12:121454288 C12orf43 -0.62 -5.3 -0.43 5.11e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs78487399 0.614 rs13422551 chr2:43724682 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.49 0.37 1.59e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg20637647 chr7:64974828 NA -0.84 -5.5 -0.44 2.07e-7 Diabetic kidney disease; TGCT cis rs4975709 0.589 rs931508 chr5:1861224 C/G cg15595755 chr5:1867978 NA 0.45 5.09 0.42 1.3e-6 Cardiovascular disease risk factors; TGCT cis rs7666738 0.830 rs13119913 chr4:98977983 G/T cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs2204008 0.744 rs66474616 chr12:38461564 G/A cg26384229 chr12:38710491 ALG10B 0.88 8.04 0.59 5.98e-13 Bladder cancer; TGCT cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg00684032 chr4:1343700 KIAA1530 -0.22 -4.73 -0.39 6.06e-6 Obesity-related traits; TGCT cis rs6088590 0.687 rs8115656 chr20:33282780 G/C cg08999081 chr20:33150536 PIGU 0.26 4.88 0.4 3.17e-6 Coronary artery disease; TGCT cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2216164 1.000 rs7304531 chr12:68521687 C/T cg17065850 chr12:67807625 NA 0.25 4.61 0.38 9.76e-6 Alopecia areata; TGCT trans rs7824557 0.564 rs4631424 chr8:11236809 T/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs9611565 0.546 rs5758430 chr22:42109844 G/T cg13695892 chr22:41940480 POLR3H 0.89 9.04 0.63 2.55e-15 Vitiligo; TGCT cis rs35934224 0.891 rs73148965 chr22:19872935 G/A cg11182965 chr22:19864308 TXNRD2 -0.35 -4.68 -0.39 7.54e-6 Glaucoma (primary open-angle); TGCT cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg00684032 chr4:1343700 KIAA1530 0.22 4.73 0.39 6.04e-6 Obesity-related traits; TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.85 0.4 3.59e-6 Prudent dietary pattern; TGCT cis rs11874712 0.899 rs11664764 chr18:43675364 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs6088590 1.000 rs2076668 chr20:33437621 G/A cg06115741 chr20:33292138 TP53INP2 0.63 5.08 0.42 1.32e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs7663661 chr4:99014761 A/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1488864 1.000 rs1552515 chr11:6354524 G/A cg12755421 chr11:6342214 PRKCDBP -0.65 -4.66 -0.39 8.1e-6 Smooth-surface caries; TGCT cis rs8084125 0.832 rs62105182 chr18:74951407 T/C cg05528293 chr18:74961138 GALR1 0.52 5.18 0.42 8.65e-7 Obesity-related traits; TGCT cis rs3125734 0.608 rs7905731 chr10:64018472 T/C cg19640130 chr10:64028056 RTKN2 -0.4 -5.14 -0.42 1.02e-6 Rheumatoid arthritis; TGCT cis rs7772486 0.875 rs2777479 chr6:146309178 C/A cg23711669 chr6:146136114 FBXO30 0.86 9.13 0.63 1.59e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2841277 0.708 rs11851053 chr14:105407208 T/C cg21017887 chr14:105400489 NA 0.37 5.19 0.42 8.23e-7 Rheumatoid arthritis; TGCT cis rs1568889 0.712 rs10835306 chr11:28302410 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 10.99 0.7 4.8e-20 Bipolar disorder; TGCT cis rs2070488 1.000 rs13058903 chr3:38513365 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.88 -9.49 -0.65 2.13e-16 Electrocardiographic conduction measures; TGCT cis rs2228479 0.764 rs7186976 chr16:89961593 A/G cg06558623 chr16:89946397 TCF25 0.5 5.99 0.47 2.14e-8 Skin colour saturation; TGCT cis rs478304 0.654 rs6591187 chr11:65460086 C/G cg27068330 chr11:65405492 SIPA1 -0.99 -11.36 -0.71 6.13e-21 Acne (severe); TGCT cis rs1153858 1.000 rs4774579 chr15:45651803 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs3101457 0.515 rs4658632 chr1:244516949 G/T cg09033006 chr1:244517177 C1orf100 -0.42 -4.59 -0.38 1.06e-5 Smoking behavior; TGCT cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs829661 0.947 rs829665 chr2:30724701 T/A cg07150166 chr2:30669952 LCLAT1 0.9 5.7 0.46 8.09e-8 Midgestational circulating levels of PBDEs (fetal genetic effect); TGCT cis rs6088580 0.634 rs1205338 chr20:32925625 C/G cg06115741 chr20:33292138 TP53INP2 -0.55 -4.84 -0.4 3.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs9894429 0.646 rs7220310 chr17:79606056 C/A cg18240062 chr17:79603768 NPLOC4 0.56 4.92 0.4 2.67e-6 Eye color traits; TGCT cis rs1371867 0.846 rs1788167 chr8:101319996 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs4730250 0.707 rs257386 chr7:106807783 C/G cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.6e-8 Osteoarthritis; TGCT trans rs17685 0.725 rs6467993 chr7:75719350 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs9902453 0.765 rs2874505 chr17:28037923 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 8.49 0.61 5.34e-14 Coffee consumption (cups per day); TGCT cis rs7617773 0.780 rs2541 chr3:48339618 A/G cg11946769 chr3:48343235 NME6 0.82 7.06 0.54 1.03e-10 Coronary artery disease; TGCT cis rs11190604 1.000 rs11190602 chr10:102297256 T/C cg23241863 chr10:102295624 HIF1AN 0.69 5.1 0.42 1.24e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4455778 0.580 rs7808248 chr7:49125067 T/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7824557 0.527 rs4634600 chr8:11239017 T/A cg21775007 chr8:11205619 TDH -0.68 -6.6 -0.51 1.08e-9 Retinal vascular caliber; TGCT cis rs4975709 1.000 rs4975709 chr5:1877280 A/C cg14773178 chr5:1868261 NA 0.35 5.12 0.42 1.14e-6 Cardiovascular disease risk factors; TGCT cis rs12142240 0.698 rs17361915 chr1:46847321 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs2153535 0.580 rs2184584 chr6:8468407 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs10782582 0.593 rs6675076 chr1:76118503 A/C cg03433033 chr1:76189801 ACADM -0.63 -7.39 -0.55 1.89e-11 Daytime sleep phenotypes; TGCT cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.84 -0.4 3.85e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2073300 1.000 rs6036422 chr20:23456962 A/T cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs6558174 0.965 rs1564595 chr8:22488939 A/G cg03733263 chr8:22462867 KIAA1967 0.67 5.4 0.44 3.33e-7 Breast cancer; TGCT cis rs8031584 1.000 rs35607976 chr15:31277788 T/C cg08704250 chr15:31115839 NA -0.35 -4.53 -0.38 1.38e-5 Huntington's disease progression; TGCT cis rs12220898 0.679 rs7082585 chr10:50486747 G/T cg12697796 chr10:49954016 WDFY4 0.51 4.58 0.38 1.1e-5 Inflammatory biomarkers; TGCT cis rs611744 0.870 rs634216 chr8:109174803 A/G cg21045802 chr8:109455806 TTC35 0.7 6.19 0.49 8.14e-9 Dupuytren's disease; TGCT cis rs2050392 0.792 rs684395 chr10:30719112 C/G cg13289132 chr10:30722225 MAP3K8 -0.39 -4.65 -0.39 8.2e-6 Inflammatory bowel disease; TGCT cis rs1878931 0.580 rs3848355 chr16:3407489 A/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.91 10.22 0.68 3.6e-18 Body mass index (adult); TGCT cis rs7267979 1.000 rs6115168 chr20:25372891 C/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4819052 0.851 rs2838826 chr21:46655785 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.53 4.54 0.38 1.34e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.830 rs34164616 chr4:99015251 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs595982 0.559 rs117227130 chr19:49367959 A/G cg17863274 chr19:49399704 TULP2 -0.47 -6.78 -0.52 4.43e-10 Red cell distribution width; TGCT cis rs7296418 0.961 rs7957096 chr12:123544878 A/G cg00376283 chr12:123451042 ABCB9 0.78 7.16 0.54 6.27e-11 Platelet count; TGCT cis rs1245541 0.681 rs1245579 chr10:73883550 C/T cg09661010 chr10:73848153 SPOCK2 -0.37 -4.53 -0.38 1.39e-5 Insulin-like growth factors; TGCT cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs3849570 0.961 rs3772896 chr3:81751968 C/T cg07356753 chr3:81810745 GBE1 -0.85 -8.16 -0.59 3.13e-13 Waist circumference;Body mass index; TGCT cis rs17401966 1.000 rs17401966 chr1:10385471 C/T cg19773385 chr1:10388646 KIF1B 0.21 4.54 0.38 1.31e-5 Hepatocellular carcinoma; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg23131131 chr22:24373011 LOC391322 -0.79 -8.48 -0.61 5.68e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12210905 1.000 rs6931711 chr6:27145586 C/T cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs9314614 0.865 rs2978898 chr8:6692378 T/C cg27319216 chr8:6693540 XKR5 -0.31 -5.13 -0.42 1.07e-6 IgA nephropathy;White blood cell count (basophil); TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg19626725 chr5:178986131 RUFY1 -0.54 -7.3 -0.55 3.09e-11 Lung cancer; TGCT cis rs9443645 0.901 rs10943605 chr6:79655477 G/A cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs950169 0.919 rs17300292 chr15:84762568 G/C cg17173187 chr15:85201210 NMB 0.47 5.23 0.43 7.01e-7 Schizophrenia; TGCT cis rs2456568 0.741 rs2102332 chr11:93635281 G/T cg16099599 chr11:93583650 C11orf90 -0.4 -4.98 -0.41 2.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10876993 0.789 rs1689600 chr12:58049645 A/T cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs4975616 0.869 rs380286 chr5:1320247 G/A cg07493874 chr5:1342172 CLPTM1L -0.28 -6.52 -0.51 1.59e-9 Lung cancer; TGCT cis rs6582630 0.555 rs7301250 chr12:38596244 G/T cg26384229 chr12:38710491 ALG10B 0.89 7.82 0.57 2e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT trans rs57221529 0.766 rs28563961 chr5:554498 C/G cg11887960 chr12:57824829 NA 1.14 9.17 0.64 1.26e-15 Lung disease severity in cystic fibrosis; TGCT cis rs7833790 0.724 rs72603871 chr8:82754460 C/G cg06027949 chr8:82754900 SNX16 0.67 5.14 0.42 1.06e-6 Diastolic blood pressure; TGCT cis rs11203032 0.831 rs10887920 chr10:90924415 C/T cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs2281845 0.965 rs3738263 chr1:201083506 A/G cg22815214 chr1:201083145 CACNA1S 0.25 4.65 0.39 8.33e-6 Permanent tooth development; TGCT cis rs655029 0.816 rs711229 chr2:31460932 G/A cg14018959 chr2:31480232 EHD3 -0.34 -4.58 -0.38 1.11e-5 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs7402982 0.934 rs8028620 chr15:99202875 C/T cg03437748 chr15:99193247 IGF1R 0.57 6.08 0.48 1.35e-8 Birth weight; TGCT cis rs6732795 0.896 rs6546485 chr2:69413745 A/G cg10773587 chr2:69614142 GFPT1 -0.51 -4.74 -0.39 5.77e-6 Intraocular pressure; TGCT cis rs10744422 1.000 rs1532835 chr12:123330665 G/A cg25930673 chr12:123319894 HIP1R -0.85 -4.94 -0.41 2.45e-6 Schizophrenia; TGCT cis rs910316 0.763 rs6574205 chr14:75453039 G/C cg08847533 chr14:75593920 NEK9 0.82 8.81 0.62 9.21e-15 Height; TGCT cis rs2387326 1.000 rs2387328 chr10:129925986 C/T cg03458096 chr10:129105057 DOCK1 -0.3 -4.67 -0.39 7.78e-6 Select biomarker traits; TGCT cis rs9291683 0.507 rs6827754 chr4:10018153 A/C cg11266682 chr4:10021025 SLC2A9 -0.68 -6.44 -0.5 2.41e-9 Bone mineral density; TGCT cis rs427394 0.772 rs274689 chr5:6736215 G/C cg10857441 chr5:6722123 POLS -0.32 -7.93 -0.58 1.08e-12 Menopause (age at onset); TGCT cis rs950169 0.920 rs12915390 chr15:84792069 T/C cg12863693 chr15:85201151 NMB 0.38 4.45 0.37 1.9e-5 Schizophrenia; TGCT cis rs4506170 0.887 rs56736364 chr8:128323724 C/T cg07795030 chr8:128802207 NA -0.21 -4.61 -0.38 9.75e-6 Prostate cancer; TGCT cis rs4635969 1.000 rs4635969 chr5:1308552 C/T cg00059399 chr5:2008272 NA -0.33 -4.6 -0.38 1.01e-5 Testicular germ cell tumor;Testicular germ cell cancer; TGCT cis rs7267979 0.934 rs4815423 chr20:25387521 A/G cg14121845 chr20:25566513 NINL -0.5 -5.4 -0.44 3.23e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs78366141 0.536 rs76432068 chr4:89624219 G/A cg01026744 chr4:89619053 NAP1L5;HERC3 1.28 5.48 0.44 2.32e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs9467773 1.000 rs28558133 chr6:26531433 G/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.51e-14 Type 2 diabetes; TGCT cis rs7104764 1.000 rs6598065 chr11:243211 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs6940638 0.715 rs9348751 chr6:27067190 T/A cg26531700 chr6:26746687 NA -0.56 -4.88 -0.4 3.25e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.844 rs2474780 chr20:25285835 G/A cg03522245 chr20:25566470 NINL 0.55 5.55 0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs595982 0.517 rs4801779 chr19:49406651 T/G cg17863274 chr19:49399704 TULP2 -0.28 -4.49 -0.37 1.64e-5 Red cell distribution width; TGCT cis rs9393777 0.778 rs35526527 chr6:27042287 C/A cg16898833 chr6:26189333 HIST1H4D 1.0 5.74 0.46 6.81e-8 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.807 rs11253513 chr10:968450 C/T cg20503657 chr10:835505 NA 0.65 9.44 0.65 2.93e-16 Eosinophil percentage of granulocytes; TGCT cis rs9300255 0.739 rs1533703 chr12:123742093 T/G cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs7085104 0.700 rs10786712 chr10:104596396 A/G cg04362960 chr10:104952993 NT5C2 -0.55 -4.92 -0.4 2.7e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg12311346 chr5:56204834 C5orf35 -0.65 -6.48 -0.5 1.99e-9 Initial pursuit acceleration; TGCT cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs910316 0.737 rs175080 chr14:75513828 G/A cg11812906 chr14:75593930 NEK9 -0.63 -5.74 -0.46 6.72e-8 Height; TGCT cis rs12497850 0.864 rs12493001 chr3:49181885 A/G cg18654377 chr3:49208889 KLHDC8B -0.38 -4.81 -0.4 4.25e-6 Parkinson's disease; TGCT cis rs597539 0.652 rs660614 chr11:68659488 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.22 0.59 2.28e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3806843 0.576 rs246009 chr5:140338069 A/G cg07102913 chr5:140593443 PCDHB13 0.47 4.7 0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs597539 0.616 rs631001 chr11:68642974 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.83 7.86 0.58 1.55e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3935685 0.967 rs62009151 chr15:77999264 C/A cg25212270 chr15:78015279 NA 0.3 6.03 0.48 1.71e-8 Intelligence (multi-trait analysis); TGCT cis rs7178424 0.516 rs8023668 chr15:62334705 T/A cg00456672 chr15:62358751 C2CD4A -0.29 -4.5 -0.37 1.57e-5 Height; TGCT trans rs1005277 0.579 rs1740742 chr10:38518860 C/T cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg25703541 chr22:24373054 LOC391322 0.82 6.94 0.53 1.89e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7826238 0.594 rs2948285 chr8:8130538 A/T cg15556689 chr8:8085844 FLJ10661 0.83 7.78 0.57 2.46e-12 Systolic blood pressure; TGCT trans rs2727020 0.729 rs34647977 chr11:49195543 G/A cg03929089 chr4:120376271 NA -0.69 -7.78 -0.57 2.48e-12 Coronary artery disease; TGCT cis rs2455799 0.613 rs6772879 chr3:15741793 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.57 -0.38 1.15e-5 Mean platelet volume; TGCT cis rs875971 1.000 rs11974219 chr7:65647410 C/T cg18876405 chr7:65276391 NA -0.33 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs7511006 0.893 rs2038049 chr22:50654888 G/C cg16473166 chr22:50639996 SELO 0.63 6.1 0.48 1.24e-8 Obesity-related traits; TGCT cis rs9914544 0.545 rs8066636 chr17:18761109 G/A cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs11577318 0.812 rs3795683 chr1:26632831 C/A cg12733254 chr1:26682999 NA -0.2 -4.49 -0.37 1.62e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2120019 1.000 rs7167285 chr15:75368769 A/G cg09165964 chr15:75287851 SCAMP5 -1.09 -8.86 -0.62 7.08e-15 Blood trace element (Zn levels); TGCT trans rs561341 0.843 rs4795666 chr17:30241409 A/G cg20587970 chr11:113659929 NA -0.86 -11.09 -0.71 2.74e-20 Hip circumference adjusted for BMI; TGCT cis rs2204008 0.547 rs12318267 chr12:38250905 T/G cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs933688 0.877 rs1477349 chr5:90707773 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.35 0.6 1.17e-13 Smoking behavior; TGCT cis rs3125734 0.633 rs4979772 chr10:63967600 C/T cg09941381 chr10:64027924 RTKN2 0.37 5.61 0.45 1.24e-7 Rheumatoid arthritis; TGCT cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs9916302 0.706 rs7503377 chr17:37708841 A/G cg07936489 chr17:37558343 FBXL20 -0.74 -5.76 -0.46 6.13e-8 Glomerular filtration rate (creatinine); TGCT trans rs114540395 0.858 rs79010936 chr10:103300909 T/C cg10198749 chr1:39920707 MACF1 0.55 7.05 0.53 1.11e-10 Schizophrenia; TGCT cis rs7666738 0.830 rs17550630 chr4:99008332 G/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 0.866 rs2371183 chr3:40334247 C/T cg13683864 chr3:40499215 RPL14 0.87 8.55 0.61 3.92e-14 Renal cell carcinoma; TGCT cis rs2742234 0.868 rs2505512 chr10:43633596 G/A cg02780029 chr10:43622663 RET -0.26 -5.03 -0.41 1.67e-6 Hirschsprung disease; TGCT cis rs1062177 0.855 rs6896664 chr5:151265274 A/G cg12924095 chr5:151150029 G3BP1 0.32 4.48 0.37 1.67e-5 Preschool internalizing problems; TGCT cis rs4845570 1.000 rs3790514 chr1:151744168 T/C cg07092448 chr1:151763213 TDRKH -1.14 -8.5 -0.61 5.08e-14 Coronary artery disease; TGCT cis rs778371 0.630 rs13007579 chr2:233725364 G/A cg08000102 chr2:233561755 GIGYF2 -0.68 -7.7 -0.57 3.81e-12 Schizophrenia; TGCT cis rs2469997 1.000 rs2469998 chr8:120354022 G/A cg00681363 chr8:120844660 TAF2 0.65 4.52 0.38 1.45e-5 Hypertension (SNP x SNP interaction); TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg25767906 chr1:53392781 SCP2 -0.62 -7.65 -0.57 4.78e-12 Monocyte count; TGCT trans rs225245 0.541 rs321612 chr17:33881631 T/C cg19694781 chr19:47549865 TMEM160 -0.36 -6.69 -0.51 6.94e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs12477438 0.501 rs2632284 chr2:99775865 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.9 9.33 0.64 5.15e-16 Chronic sinus infection; TGCT cis rs17345786 1.000 rs17345528 chr3:101294830 A/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.55 -4.69 -0.39 7.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.934 rs35201724 chr4:1310717 C/G cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.4 2.56e-6 Obesity-related traits; TGCT cis rs7267979 0.789 rs62213729 chr20:25363426 C/T cg03522245 chr20:25566470 NINL -0.52 -5.23 -0.43 6.85e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs9388451 0.869 rs7764016 chr6:126070789 T/G cg05039488 chr6:79577232 IRAK1BP1 -0.75 -8.53 -0.61 4.37e-14 Brugada syndrome; TGCT cis rs7959452 0.562 rs10878975 chr12:69782044 G/C cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs2243480 1.000 rs709607 chr7:65449541 C/G cg07424592 chr7:64974309 NA -1.41 -8.37 -0.6 1.03e-13 Diabetic kidney disease; TGCT cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.42e-9 Bipolar disorder; TGCT cis rs13188771 0.614 rs66592082 chr5:100914515 T/C cg18665594 chr5:101119420 NA 0.44 4.57 0.38 1.17e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs6684514 1.000 rs11264462 chr1:156241728 G/A cg16558208 chr1:156270281 VHLL 0.48 9.46 0.65 2.55e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2404602 0.716 rs67418609 chr15:76627089 C/A cg26408565 chr15:76604113 ETFA -0.45 -6.09 -0.48 1.28e-8 Blood metabolite levels; TGCT cis rs7714584 1.000 rs17800886 chr5:150309539 C/G cg22134413 chr5:150180641 NA 1.04 7.44 0.56 1.48e-11 Crohn's disease; TGCT cis rs344364 0.511 rs2982452 chr16:1949511 G/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs938554 0.513 rs11943372 chr4:9999346 T/A cg11266682 chr4:10021025 SLC2A9 0.5 4.88 0.4 3.23e-6 Blood metabolite levels; TGCT cis rs2832191 0.692 rs8134627 chr21:30349069 C/T cg08807101 chr21:30365312 RNF160 -0.65 -6.01 -0.47 1.96e-8 Dental caries; TGCT cis rs17376456 0.877 rs9314093 chr5:93333347 G/A cg09848695 chr5:92956644 FAM172A;MIR2277 0.62 4.44 0.37 1.98e-5 Diabetic retinopathy; TGCT cis rs12541335 0.692 rs2290274 chr8:22214374 C/T cg07298985 chr8:22133076 PIWIL2 0.34 5.22 0.42 7.46e-7 Hypertriglyceridemia; TGCT cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg16049864 chr8:95962084 TP53INP1 -0.75 -10.73 -0.69 2.15e-19 Type 2 diabetes; TGCT cis rs9814567 0.727 rs7430034 chr3:134342127 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.29 -0.49 4.95e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs17152411 0.895 rs7914206 chr10:126585397 G/A cg07906193 chr10:126599966 NA 0.41 5.06 0.41 1.46e-6 Height; TGCT cis rs3733585 0.648 rs13125029 chr4:9982029 A/G cg00071950 chr4:10020882 SLC2A9 0.57 6.62 0.51 9.8e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs57994353 0.826 rs34619169 chr9:139327277 G/A cg13741927 chr9:139327495 INPP5E -0.27 -6.3 -0.49 4.64e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs6450176 0.953 rs3776724 chr5:53292270 A/G ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs8084125 0.832 rs56301307 chr18:74942711 A/G cg05528293 chr18:74961138 GALR1 0.5 4.75 0.39 5.61e-6 Obesity-related traits; TGCT cis rs3784262 1.000 rs4646629 chr15:58255215 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.7 -0.57 3.78e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs986417 1.000 rs1313243 chr14:60876398 C/T cg27398547 chr14:60952738 C14orf39 -1.42 -8.68 -0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs11650494 0.908 rs111834333 chr17:47411814 C/T cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs12643440 0.538 rs12641321 chr4:17141393 G/C cg22650099 chr4:17144496 NA -0.45 -4.65 -0.39 8.28e-6 Metabolite levels (Pyroglutamine); TGCT cis rs6671200 0.510 rs35556400 chr1:95916885 G/A cg20701556 chr1:95698924 RWDD3 0.72 5.36 0.43 3.95e-7 Stearic acid (18:0) levels; TGCT cis rs394563 0.591 rs237026 chr6:149720681 G/A cg03678062 chr6:149772716 ZC3H12D -0.38 -4.82 -0.4 4.12e-6 Dupuytren's disease; TGCT cis rs6088580 0.634 rs13041646 chr20:33082881 T/A cg08999081 chr20:33150536 PIGU 0.28 5.56 0.45 1.6e-7 Glomerular filtration rate (creatinine); TGCT cis rs1862618 0.671 rs2591958 chr5:56239369 C/G cg12311346 chr5:56204834 C5orf35 0.57 6.13 0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs9479482 1.000 rs9479482 chr6:150358012 T/C cg03788504 chr6:150331562 NA -0.24 -4.58 -0.38 1.12e-5 Alopecia areata; TGCT cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs1005224 0.520 rs6574249 chr14:76087152 A/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.61 -4.63 -0.38 9.26e-6 Large artery stroke; TGCT cis rs7959452 0.640 rs4274230 chr12:69700772 T/G cg20891283 chr12:69753455 YEATS4 0.66 6.57 0.51 1.26e-9 Blood protein levels; TGCT cis rs2153904 0.793 rs1891091 chr1:205661418 A/G cg23034840 chr1:205782522 SLC41A1 0.82 5.08 0.41 1.36e-6 Prostate-specific antigen levels; TGCT cis rs586688 0.543 rs1267115 chr1:201676312 A/G cg07139329 chr1:201708558 NAV1 -0.44 -4.76 -0.39 5.2e-6 Obesity-related traits; TGCT cis rs10089 1.000 rs1962291 chr5:127445373 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.84 -8.19 -0.59 2.7e-13 Ileal carcinoids; TGCT cis rs7412746 0.658 rs4537557 chr1:150734436 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.63 0.38 9.12e-6 Melanoma; TGCT cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg13395646 chr4:1353034 KIAA1530 0.38 4.58 0.38 1.1e-5 Obesity-related traits; TGCT cis rs916888 0.773 rs199439 chr17:44793503 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 -0.61 -5.07 -0.41 1.42e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.09 -15.68 -0.82 3.31e-31 Prudent dietary pattern; TGCT cis rs7584330 0.554 rs6739456 chr2:238385092 G/C cg14458575 chr2:238380390 NA 0.48 4.47 0.37 1.73e-5 Prostate cancer; TGCT cis rs11650494 0.908 rs57390430 chr17:47374886 G/A cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs36051895 0.658 rs10815145 chr9:5013309 G/A cg02405213 chr9:5042618 JAK2 -0.78 -10.83 -0.7 1.2e-19 Pediatric autoimmune diseases; TGCT cis rs2242116 1.000 rs2242116 chr3:46941116 A/G cg02527881 chr3:46936655 PTH1R -0.31 -5.84 -0.46 4.36e-8 Birth weight; TGCT cis rs7208859 0.673 rs216424 chr17:28943064 T/G cg19761014 chr17:28927070 LRRC37B2 0.55 4.7 0.39 6.92e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2412819 0.597 rs78282429 chr15:43922003 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.68 0.39 7.31e-6 Lung cancer; TGCT cis rs4819052 1.000 rs13053002 chr21:46677854 C/T cg06618935 chr21:46677482 NA -0.39 -5.08 -0.42 1.34e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1008375 0.897 rs1006723 chr4:17618524 G/A cg10189774 chr4:17578691 LAP3 0.62 5.24 0.43 6.72e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2535633 0.602 rs2581816 chr3:53014657 C/T cg11645453 chr3:52864694 ITIH4 0.27 5.08 0.41 1.37e-6 Body mass index; TGCT cis rs4819052 0.851 rs2838850 chr21:46671445 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs35306767 0.761 rs34480046 chr10:1027440 A/G cg26597838 chr10:835615 NA 0.58 6.55 0.51 1.35e-9 Eosinophil percentage of granulocytes; TGCT cis rs1670533 1.000 rs2290410 chr4:1052078 A/T cg27284194 chr4:1044797 NA 0.63 5.03 0.41 1.68e-6 Recombination rate (females); TGCT cis rs78487399 0.908 rs77613902 chr2:43843991 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.58 0.38 1.12e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10791097 0.694 rs2155752 chr11:130755998 C/T cg05962950 chr11:130786565 SNX19 0.9 11.06 0.7 3.32e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7296418 0.580 rs78455769 chr12:123856443 G/A cg00376283 chr12:123451042 ABCB9 0.64 5.49 0.44 2.18e-7 Platelet count; TGCT cis rs3924048 0.559 rs6541037 chr1:12626155 A/G cg00291366 chr1:12616550 NA 0.31 4.88 0.4 3.17e-6 Optic cup area; TGCT cis rs2404602 1.000 rs2056544 chr15:76826003 G/A cg26408565 chr15:76604113 ETFA -0.41 -5.18 -0.42 8.71e-7 Blood metabolite levels; TGCT cis rs854765 0.647 rs7406744 chr17:17981938 C/G cg09796270 chr17:17721594 SREBF1 0.23 4.71 0.39 6.6e-6 Total body bone mineral density; TGCT cis rs17221829 0.764 rs7945447 chr11:89386070 A/G cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs10207060 0.778 rs6543581 chr2:240702308 C/T cg20800816 chr2:241070422 MYEOV2 -0.18 -4.46 -0.37 1.81e-5 Obesity-related traits; TGCT cis rs1505368 0.567 rs2054617 chr2:213355890 T/C cg16329650 chr2:213403929 ERBB4 0.83 9.72 0.66 6.19e-17 Symmetrical dimethylarginine levels; TGCT cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg06634786 chr22:41940651 POLR3H -0.9 -8.98 -0.63 3.59e-15 Vitiligo; TGCT cis rs727505 0.954 rs67870530 chr7:124591878 A/G cg23710748 chr7:124431027 NA -0.26 -4.52 -0.38 1.41e-5 Lewy body disease; TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg08736216 chr1:53307985 ZYG11A -0.25 -4.82 -0.4 4.11e-6 Monocyte count; TGCT cis rs9399137 0.507 rs12664898 chr6:135288663 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs769267 0.895 rs2916069 chr19:19520358 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.51 0.5 1.71e-9 Tonsillectomy; TGCT cis rs6964587 0.869 rs6964050 chr7:91482418 C/T cg17063962 chr7:91808500 NA -0.85 -9.05 -0.63 2.54e-15 Breast cancer; TGCT trans rs2727020 0.612 rs603672 chr11:49234566 T/A cg15704280 chr7:45808275 SEPT13 0.7 7.64 0.57 5e-12 Coronary artery disease; TGCT cis rs67340775 0.541 rs200975 chr6:27855625 G/T cg26587870 chr6:27730563 NA -0.34 -4.62 -0.38 9.28e-6 Lung cancer in ever smokers; TGCT cis rs11190604 0.943 rs3750632 chr10:102279295 G/C cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs589448 0.538 rs622656 chr12:69753595 C/T cg14784868 chr12:69753453 YEATS4 0.66 5.92 0.47 2.97e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg06481639 chr22:41940642 POLR3H -0.69 -6.02 -0.48 1.83e-8 Vitiligo; TGCT cis rs1048238 0.525 rs848214 chr1:16265422 A/G cg22431228 chr1:16359049 CLCNKA 0.23 4.48 0.37 1.67e-5 Systolic blood pressure; TGCT cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg13395646 chr4:1353034 KIAA1530 -0.4 -5.0 -0.41 1.93e-6 Obesity-related traits; TGCT cis rs11874712 0.933 rs8097521 chr18:43666952 C/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs9581857 0.579 rs75326986 chr13:27997758 C/T cg22138327 chr13:27999177 GTF3A 0.79 5.51 0.44 1.99e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6088580 0.634 rs6088478 chr20:32971719 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs17384381 0.859 rs12130591 chr1:85904985 C/T cg16011679 chr1:85725395 C1orf52 0.83 6.77 0.52 4.61e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 1.000 rs17040322 chr2:26351274 G/C cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT trans rs208515 0.556 rs12214562 chr6:66681011 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs7043114 0.525 rs4744134 chr9:95246833 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.53 5.14 0.42 1.03e-6 Height; TGCT cis rs5769765 0.778 rs8137331 chr22:50313358 G/C cg15316289 chr22:50310904 ALG12;CRELD2 0.4 5.67 0.45 9.72e-8 Schizophrenia; TGCT cis rs7264396 0.561 rs6142474 chr20:34574914 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.28 4.83 0.4 3.95e-6 Total cholesterol levels; TGCT cis rs9858542 0.953 rs6446272 chr3:49463287 G/A cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7666738 0.830 rs62318503 chr4:98935479 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7829975 0.600 rs1719381 chr8:8602344 T/C cg15556689 chr8:8085844 FLJ10661 -0.65 -5.67 -0.45 9.37e-8 Mood instability; TGCT cis rs7666738 0.800 rs11941885 chr4:99072921 A/C cg17366294 chr4:99064904 C4orf37 0.76 7.61 0.56 6.06e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.811 rs12368410 chr12:38305705 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.81 0.4 4.2e-6 Bladder cancer; TGCT cis rs8062405 1.000 rs1987472 chr16:28825777 C/T cg09754948 chr16:28834200 ATXN2L 0.62 4.69 0.39 6.95e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg10047753 chr17:41438598 NA 0.9 8.32 0.6 1.37e-13 Menopause (age at onset); TGCT cis rs17534004 1.000 rs71436418 chr13:31455888 G/A cg13251181 chr13:31481184 C13orf33 0.35 4.71 0.39 6.65e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs17221829 0.733 rs11600976 chr11:89360842 A/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs61990749 0.597 rs176946 chr14:78178439 C/T cg23188588 chr14:78226832 SNW1;C14orf178 0.69 5.02 0.41 1.72e-6 Fibroblast growth factor basic levels; TGCT cis rs12497850 1.000 rs4858798 chr3:48727112 C/T cg18654377 chr3:49208889 KLHDC8B -0.43 -5.94 -0.47 2.74e-8 Parkinson's disease; TGCT cis rs9291683 0.585 rs12648479 chr4:10104571 G/A cg00071950 chr4:10020882 SLC2A9 -0.49 -5.27 -0.43 5.88e-7 Bone mineral density; TGCT cis rs910316 0.967 rs8013444 chr14:75661981 A/G cg11812906 chr14:75593930 NEK9 -0.71 -6.8 -0.52 3.94e-10 Height; TGCT trans rs7618501 1.000 rs60205400 chr3:49800272 C/T cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs11690935 0.595 rs788171 chr2:172921832 A/G cg13550731 chr2:172543902 DYNC1I2 0.69 6.36 0.5 3.49e-9 Schizophrenia; TGCT cis rs826838 0.559 rs1843891 chr12:38617018 T/C cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Heart rate; TGCT cis rs877282 0.891 rs34383514 chr10:800181 T/C cg17470449 chr10:769945 NA 0.31 4.64 0.38 8.88e-6 Uric acid levels; TGCT cis rs12681288 0.782 rs2600498 chr8:1026520 A/G cg04851639 chr8:1020857 NA -0.32 -5.75 -0.46 6.63e-8 Schizophrenia; TGCT cis rs11105298 0.786 rs10858897 chr12:89922032 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2836633 0.895 rs2836598 chr21:40024758 C/G cg12884169 chr21:40033163 ERG 0.42 4.44 0.37 1.95e-5 Coronary artery disease; TGCT trans rs916888 0.773 rs199451 chr17:44801784 G/A cg22968622 chr17:43663579 NA 1.29 11.46 0.72 3.61e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9341808 0.718 rs9352801 chr6:80817468 G/T cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs797680 0.786 rs1593512 chr1:93858374 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.47 -0.44 2.34e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2562456 0.876 rs11668606 chr19:21737420 T/G cg01304269 chr19:21688519 ZNF429 0.57 4.74 0.39 5.86e-6 Pain; TGCT trans rs2624839 0.704 rs12637671 chr3:50224562 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.77 -6.89 -0.53 2.47e-10 Intelligence (multi-trait analysis); TGCT cis rs7044106 0.762 rs1470307 chr9:123433039 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.43 0.5 2.55e-9 Hip circumference adjusted for BMI; TGCT cis rs12220238 0.722 rs7921187 chr10:76377501 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.59 4.54 0.38 1.29e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7980687 0.628 rs2851443 chr12:123694250 C/T cg00376283 chr12:123451042 ABCB9 0.79 6.8 0.52 3.88e-10 Height;Educational attainment;Head circumference (infant); TGCT cis rs2742417 0.935 rs2742393 chr3:45757417 T/A cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg13395646 chr4:1353034 KIAA1530 0.4 4.95 0.41 2.34e-6 Obesity-related traits; TGCT cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs1552244 1.000 rs6764168 chr3:10123805 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.0 0.47 1.98e-8 Alzheimer's disease; TGCT cis rs6088590 0.930 rs6120723 chr20:33364655 C/T cg24642439 chr20:33292090 TP53INP2 0.7 6.22 0.49 7.12e-9 Coronary artery disease; TGCT cis rs478304 0.934 rs570954 chr11:65498261 A/G cg27068330 chr11:65405492 SIPA1 0.75 7.39 0.55 1.93e-11 Acne (severe); TGCT cis rs7000551 0.556 rs12674913 chr8:22263617 G/C cg12081754 chr8:22256438 SLC39A14 0.37 5.38 0.44 3.57e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10206020 0.842 rs7609325 chr2:1574718 G/A cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs933688 1.000 rs6867219 chr5:90718008 T/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.98 8.36 0.6 1.11e-13 Smoking behavior; TGCT cis rs813218 0.523 rs497868 chr3:99450187 G/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.04 0.41 1.59e-6 Orofacial clefts; TGCT cis rs28595532 0.920 rs55671478 chr4:119753811 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg05457628 chr5:178986728 RUFY1 -0.53 -6.0 -0.47 1.99e-8 Lung cancer; TGCT cis rs4689388 0.929 rs1046320 chr4:6304344 C/T cg14416269 chr4:6271139 WFS1 0.36 4.73 0.39 6.02e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs478607 1.000 rs60159753 chr11:64479112 G/T cg19395706 chr11:64412079 NRXN2 0.52 5.43 0.44 2.79e-7 Urate levels; TGCT cis rs6725041 0.547 rs61696052 chr2:213201295 G/C cg20637307 chr2:213403960 ERBB4 -0.53 -4.49 -0.37 1.63e-5 QT interval (ambient particulate matter interaction); TGCT cis rs208520 0.690 rs1318604 chr6:66825278 A/C cg07460842 chr6:66804631 NA -0.95 -9.88 -0.66 2.43e-17 Exhaled nitric oxide output; TGCT trans rs7248779 0.512 rs3848635 chr19:2410332 T/C cg25835954 chr13:50160062 RCBTB1 0.75 6.89 0.53 2.52e-10 Cortisol levels (saliva); TGCT cis rs7570971 1.000 rs6730157 chr2:135907088 C/T cg07169764 chr2:136633963 MCM6 -0.55 -4.9 -0.4 2.94e-6 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs899997 1.000 rs4887078 chr15:79011073 C/T cg00061860 chr15:78953028 NA -0.25 -4.67 -0.39 7.76e-6 Coronary artery disease or large artery stroke; TGCT cis rs66573146 0.831 rs6832482 chr4:7023433 A/T cg00086871 chr4:6988644 TBC1D14 0.93 4.53 0.38 1.35e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs11096990 0.634 rs2062229 chr4:39286766 A/C cg20847110 chr4:39482781 LOC401127 0.16 4.46 0.37 1.81e-5 Cognitive function; TGCT cis rs9303401 0.659 rs12600349 chr17:57054245 A/G cg10487724 chr17:56770010 TEX14;RAD51C -0.66 -6.09 -0.48 1.32e-8 Cognitive test performance; TGCT cis rs9303401 0.614 rs56284918 chr17:57178838 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs7914558 0.966 rs1971589 chr10:104744406 A/G cg04362960 chr10:104952993 NT5C2 0.6 5.42 0.44 2.99e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3770081 1.000 rs2278086 chr2:86281905 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs9430161 0.644 rs34365965 chr1:11034442 G/A cg27631724 chr1:11040367 C1orf127 0.52 5.95 0.47 2.57e-8 Ewing sarcoma; TGCT cis rs175714 0.845 rs175702 chr14:75971133 G/T cg01624173 chr14:75981868 NA -0.38 -7.07 -0.54 9.92e-11 Lymphocyte counts; TGCT cis rs6570726 0.599 rs426371 chr6:145886469 A/G cg13319975 chr6:146136371 FBXO30 0.69 6.27 0.49 5.34e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs17253792 0.822 rs77315200 chr14:56072643 C/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6912958 0.559 rs242280 chr6:88048714 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.72 7.53 0.56 9.05e-12 Monocyte percentage of white cells; TGCT cis rs11030122 0.702 rs17081 chr11:3987830 A/G cg18678763 chr11:4115507 RRM1 0.49 6.13 0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs13242816 0.881 rs13235183 chr7:116140149 G/T cg02799643 chr7:116139180 CAV2 -0.42 -5.45 -0.44 2.55e-7 P wave duration; TGCT cis rs899997 1.000 rs7182694 chr15:79045030 C/T cg00061860 chr15:78953028 NA -0.27 -4.67 -0.39 7.62e-6 Coronary artery disease or large artery stroke; TGCT cis rs4727027 0.870 rs62507485 chr7:148764182 C/T cg23583168 chr7:148888333 NA -0.69 -8.72 -0.62 1.5e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6088580 0.634 rs6058052 chr20:33047084 A/G cg08999081 chr20:33150536 PIGU 0.28 5.6 0.45 1.3e-7 Glomerular filtration rate (creatinine); TGCT cis rs7772486 0.754 rs702324 chr6:146008793 A/G cg23711669 chr6:146136114 FBXO30 -0.93 -10.4 -0.68 1.33e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs559928 0.606 rs7941773 chr11:63952759 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.57 0.38 1.18e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs875971 0.666 rs13242072 chr7:65765988 A/G cg00343986 chr7:65444356 GUSB -0.21 -4.57 -0.38 1.15e-5 Aortic root size; TGCT cis rs7666738 0.830 rs28416660 chr4:98899525 C/G cg18180107 chr4:99064573 C4orf37 0.53 4.81 0.4 4.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7572733 0.534 rs700674 chr2:198693703 C/T cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT trans rs3107575 0.572 rs73169366 chr3:165320307 C/T cg03961853 chr1:230384989 GALNT2 0.64 6.9 0.53 2.41e-10 Morning vs. evening chronotype; TGCT cis rs6964587 0.967 rs34344935 chr7:91835436 G/A cg22709100 chr7:91322751 NA 0.29 4.49 0.37 1.59e-5 Breast cancer; TGCT cis rs2153535 0.580 rs2327051 chr6:8441150 A/G cg23788917 chr6:8435910 SLC35B3 -0.54 -4.61 -0.38 9.84e-6 Motion sickness; TGCT cis rs6964587 1.000 rs10225885 chr7:91671007 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs9296661 0.522 rs9474070 chr6:51647813 C/T cg20180370 chr6:50691003 TFAP2D -0.48 -4.68 -0.39 7.35e-6 Weight loss (gastric bypass surgery); TGCT cis rs7666738 0.925 rs34423396 chr4:99049031 T/A cg17366294 chr4:99064904 C4orf37 0.71 6.53 0.51 1.55e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs1018836 0.851 rs7007129 chr8:91629790 T/G cg16814680 chr8:91681699 NA -0.82 -8.6 -0.61 2.86e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs137603 0.644 rs137620 chr22:39709776 T/C cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.75 -0.39 5.59e-6 Primary biliary cholangitis; TGCT cis rs11586313 0.507 rs6658967 chr1:152870372 C/G cg07796016 chr1:152779584 LCE1C -0.44 -5.0 -0.41 1.91e-6 Vitamin D levels; TGCT cis rs2692947 0.550 rs4613327 chr2:96583823 G/A cg23100626 chr2:96804247 ASTL 0.38 4.61 0.38 9.79e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6424115 0.708 rs11803575 chr1:24182348 A/T cg15997130 chr1:24165203 NA -0.69 -6.99 -0.53 1.51e-10 Immature fraction of reticulocytes; TGCT cis rs6933660 0.745 rs9397405 chr6:151736084 G/T cg10883421 chr6:151773342 RMND1;C6orf211 0.65 6.4 0.5 2.88e-9 Menarche (age at onset); TGCT cis rs4665809 1.000 rs1030730 chr2:26284143 T/C cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs4074961 0.692 rs11264075 chr1:38083941 C/G cg11397548 chr1:38022522 DNALI1 0.45 5.01 0.41 1.84e-6 Axial length; TGCT trans rs4650994 0.524 rs2209170 chr1:178607388 C/A cg05059571 chr16:84539110 KIAA1609 0.52 10.36 0.68 1.73e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs17221829 0.702 rs12360859 chr11:89359887 A/G cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs13217239 0.646 rs7768407 chr6:27016795 G/A cg15659132 chr6:26577336 NA 0.59 6.0 0.47 1.97e-8 Schizophrenia; TGCT cis rs12142240 0.698 rs1475389 chr1:46816429 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs10504229 0.906 rs2270607 chr8:58194699 A/G cg24829409 chr8:58192753 C8orf71 -0.5 -4.64 -0.38 8.89e-6 Developmental language disorder (linguistic errors); TGCT cis rs6933660 0.745 rs9397405 chr6:151736084 G/T cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.66 0.39 7.87e-6 Menarche (age at onset); TGCT cis rs2806561 0.734 rs7548692 chr1:23354877 T/A cg12483005 chr1:23474871 LUZP1 0.38 4.76 0.39 5.3e-6 Height; TGCT cis rs797680 0.964 rs797668 chr1:93694789 C/G cg17826107 chr1:92977322 EVI5 0.24 5.3 0.43 5.16e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg27286337 chr10:134555280 INPP5A 0.41 4.98 0.41 2.05e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17122693 0.748 rs72679596 chr14:51103595 C/T cg04730355 chr14:51134070 SAV1 1.34 11.9 0.73 2.97e-22 Cognitive performance; TGCT cis rs922182 0.633 rs4776698 chr15:64267534 C/A cg02919090 chr15:64263738 DAPK2 -0.29 -5.08 -0.42 1.33e-6 Blood protein levels; TGCT cis rs9400467 0.537 rs17606672 chr6:111546833 G/C cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs2688608 0.592 rs12253482 chr10:75496130 G/A cg04320760 chr10:75533139 FUT11 -0.39 -5.94 -0.47 2.64e-8 Inflammatory bowel disease; TGCT cis rs2204008 0.805 rs4882575 chr12:37940573 G/A cg26384229 chr12:38710491 ALG10B -0.73 -6.33 -0.49 4.02e-9 Bladder cancer; TGCT cis rs10493389 0.673 rs4310419 chr1:66286459 A/G cg08716655 chr1:66257732 PDE4B -0.42 -4.59 -0.38 1.06e-5 Echocardiographic traits; TGCT cis rs977747 0.843 rs4134058 chr1:47670911 T/C cg03885399 chr1:47691550 TAL1 -0.43 -5.42 -0.44 2.97e-7 Body mass index; TGCT cis rs1577917 0.958 rs6454488 chr6:86450842 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.17 -0.42 9.02e-7 Response to antipsychotic treatment; TGCT cis rs7917772 0.582 rs10786683 chr10:104320476 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7772486 0.686 rs2328708 chr6:146095739 G/A cg23711669 chr6:146136114 FBXO30 -0.84 -9.35 -0.64 4.84e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1371867 0.875 rs1612773 chr8:101337818 G/C cg06002616 chr8:101225028 SPAG1 -0.54 -6.21 -0.49 7.43e-9 Atrioventricular conduction; TGCT cis rs6940638 0.956 rs12190473 chr6:27024687 C/T cg26531700 chr6:26746687 NA -0.6 -4.58 -0.38 1.1e-5 Intelligence (multi-trait analysis); TGCT cis rs6988636 1.000 rs57322232 chr8:124193532 A/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs4824093 0.545 rs58876234 chr22:50258868 G/A cg14114931 chr22:50943910 LMF2 0.37 4.58 0.38 1.11e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6089829 0.926 rs1060491 chr20:61665817 C/A cg18188782 chr20:61659543 NA -0.43 -5.11 -0.42 1.17e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs7678911 chr4:99057430 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7178572 0.568 rs11072653 chr15:77693934 C/T cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs6840360 0.571 rs7685697 chr4:152558849 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs9549367 0.664 rs9549689 chr13:113848387 G/A cg09473364 chr13:112927190 NA -0.3 -4.6 -0.38 1.01e-5 Platelet distribution width; TGCT cis rs11696501 0.789 rs1487319 chr20:44295943 A/G cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs853679 0.546 rs200989 chr6:27816442 A/G cg08798685 chr6:27730294 NA -0.34 -4.77 -0.39 5.13e-6 Depression; TGCT cis rs3617 0.559 rs11915546 chr3:52866845 A/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs16986825 0.664 rs5997409 chr22:29222096 T/C cg02153584 chr22:29168773 CCDC117 0.78 5.37 0.43 3.81e-7 Pancreatic cancer; TGCT cis rs8180040 0.966 rs11130129 chr3:47489885 G/C cg27129171 chr3:47204927 SETD2 -0.66 -7.84 -0.58 1.75e-12 Colorectal cancer; TGCT cis rs2070488 1.000 rs2070488 chr3:38442490 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.9 -9.65 -0.66 8.79e-17 Electrocardiographic conduction measures; TGCT cis rs10883723 0.962 rs1056741 chr10:104236640 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 7.52 0.56 9.74e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs8031584 0.958 rs34909055 chr15:31284170 C/T cg19680485 chr15:31195859 MTMR15 -0.51 -4.54 -0.38 1.31e-5 Huntington's disease progression; TGCT cis rs6952808 0.729 rs35797753 chr7:1954914 G/A cg04267008 chr7:1944627 MAD1L1 -0.35 -4.53 -0.38 1.35e-5 Bipolar disorder and schizophrenia; TGCT cis rs8177179 0.967 rs9820225 chr3:133449189 A/G cg16262614 chr3:133464971 TF 0.35 4.72 0.39 6.28e-6 Iron status biomarkers (transferrin levels); TGCT cis rs6121246 0.529 rs6120862 chr20:30199459 T/C cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs13191362 1.000 rs13210756 chr6:163009030 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg22764044 chr5:178986830 RUFY1 0.44 4.76 0.39 5.36e-6 Lung cancer; TGCT cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4601821 1.000 rs6589375 chr11:113255111 C/A cg14159747 chr11:113255604 NA 0.38 4.43 0.37 2.01e-5 Alcoholic chronic pancreatitis; TGCT cis rs6669384 0.774 rs7551724 chr1:208030856 C/T cg22525895 chr1:207977042 MIR29B2 -0.38 -5.31 -0.43 4.83e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs344364 0.511 rs1742467 chr16:1950187 G/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs739401 0.572 rs7111857 chr11:3068106 A/G cg25174290 chr11:3078921 CARS -0.49 -4.87 -0.4 3.34e-6 Longevity; TGCT cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs4517514 0.509 rs4385851 chr11:89870750 C/T cg14505434 chr11:89522851 NA 0.45 4.45 0.37 1.87e-5 Trans fatty acid levels; TGCT cis rs12135062 0.755 rs1553287 chr1:3101277 G/A cg25382214 chr1:3105252 PRDM16 -0.27 -4.58 -0.38 1.12e-5 Migraine; TGCT cis rs12510870 0.599 rs7682201 chr4:74450830 C/T cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs112591243 0.685 rs78443123 chr21:47953331 G/T cg10657630 chr21:48055338 PRMT2 1.06 5.21 0.42 7.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs2230307 0.536 rs640030 chr1:100574992 C/T cg24955406 chr1:100503596 HIAT1 -0.75 -5.11 -0.42 1.19e-6 Carotid intima media thickness; TGCT cis rs4711350 0.862 rs487835 chr6:33710933 G/A cg00334056 chr6:33755658 LEMD2 0.31 4.81 0.4 4.31e-6 Schizophrenia; TGCT cis rs7528419 1.000 rs12740374 chr1:109817590 G/T cg00908766 chr1:109817496 CELSR2 -0.52 -5.38 -0.43 3.62e-7 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs765787 0.530 rs1706837 chr15:45519036 A/G cg24006582 chr15:45444508 DUOX1 -0.26 -5.75 -0.46 6.51e-8 Uric acid levels; TGCT cis rs3733585 0.699 rs6449177 chr4:9968050 T/C cg11266682 chr4:10021025 SLC2A9 -0.57 -7.38 -0.55 2.03e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1775715 0.677 rs2808105 chr10:32110907 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.38e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs7727544 0.735 rs274566 chr5:131715011 A/G cg24060327 chr5:131705240 SLC22A5 0.59 6.62 0.51 9.73e-10 Blood metabolite levels; TGCT cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg05368731 chr17:41323189 NBR1 1.04 11.64 0.72 1.25e-21 Menopause (age at onset); TGCT cis rs7909074 1.000 rs7909074 chr10:45395839 G/A cg05187965 chr10:45406764 TMEM72 -0.24 -5.23 -0.42 7.12e-7 Mean corpuscular volume; TGCT trans rs1496653 0.602 rs35902312 chr3:23387013 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs3796352 1.000 rs2564926 chr3:53094730 G/A cg27565382 chr3:53032988 SFMBT1 -0.42 -4.48 -0.37 1.68e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7428 0.545 rs2366404 chr2:85551779 G/A cg24342717 chr2:85555507 TGOLN2 -0.48 -8.09 -0.59 4.64e-13 Ear protrusion; TGCT trans rs916888 0.738 rs199515 chr17:44856641 C/G cg22968622 chr17:43663579 NA -1.19 -10.3 -0.68 2.4e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs4332037 0.539 rs55988458 chr7:2059761 G/A cg25206134 chr2:45395956 NA 0.96 7.31 0.55 2.89e-11 Bipolar disorder; TGCT cis rs9811920 0.732 rs7613864 chr3:99602470 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.46 -5.2 -0.42 7.88e-7 Axial length; TGCT cis rs9831754 0.865 rs9842838 chr3:78387904 A/C cg06138941 chr3:78371609 NA -0.49 -5.4 -0.44 3.25e-7 Calcium levels; TGCT cis rs35883536 0.588 rs955338 chr1:101108794 G/C cg06223162 chr1:101003688 GPR88 0.34 5.67 0.45 9.44e-8 Monocyte count; TGCT cis rs2012796 1.000 rs10450939 chr14:81825202 A/T cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs4851266 1.000 rs4851267 chr2:100824104 G/A cg22139774 chr2:100720529 AFF3 -0.36 -5.4 -0.44 3.26e-7 Educational attainment; TGCT cis rs73001065 0.901 rs73002956 chr19:19578743 A/G cg03709012 chr19:19516395 GATAD2A 1.04 5.02 0.41 1.74e-6 LDL cholesterol; TGCT cis rs10744422 1.000 rs3852536 chr12:123333824 C/T cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs6903823 0.508 rs1150726 chr6:28243042 C/T cg18815343 chr6:28367644 ZSCAN12 -0.44 -4.58 -0.38 1.13e-5 Pulmonary function; TGCT cis rs2836974 1.000 rs12710454 chr21:40656919 A/G cg11890956 chr21:40555474 PSMG1 1.05 11.11 0.71 2.44e-20 Cognitive function; TGCT cis rs1371867 0.875 rs1788173 chr8:101330939 A/G cg06636551 chr8:101224915 SPAG1 0.42 5.63 0.45 1.15e-7 Atrioventricular conduction; TGCT cis rs7119 0.717 rs12902912 chr15:77809170 A/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.59 -0.38 1.06e-5 Type 2 diabetes; TGCT cis rs12681287 0.640 rs12541793 chr8:87462558 G/A cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs13088645 0.652 rs13074557 chr3:134153526 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.64 6.02 0.48 1.83e-8 Coronary artery disease; TGCT cis rs3849570 0.961 rs11710970 chr3:81693489 T/C cg07356753 chr3:81810745 GBE1 -0.84 -7.74 -0.57 3.01e-12 Waist circumference;Body mass index; TGCT cis rs1568889 0.838 rs6484359 chr11:28262328 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.91 9.93 0.67 1.82e-17 Bipolar disorder; TGCT cis rs1005277 0.579 rs1780136 chr10:38501453 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7829975 0.539 rs4841012 chr8:8551710 C/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.31 -0.43 4.81e-7 Mood instability; TGCT cis rs9611519 0.894 rs4821998 chr22:41468273 C/G cg13695892 chr22:41940480 POLR3H -0.54 -4.78 -0.39 4.93e-6 Neuroticism; TGCT cis rs7666738 0.830 rs28867388 chr4:98962794 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.12 15.17 0.81 4.81e-30 Height; TGCT cis rs6988636 1.000 rs28624331 chr8:124190768 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs7432375 0.610 rs56695781 chr3:136510601 G/T cg15507776 chr3:136538369 TMEM22 0.55 5.64 0.45 1.1e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9486715 0.838 rs7452350 chr6:96883326 C/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg17264618 chr3:40429014 ENTPD3 -0.3 -4.48 -0.37 1.65e-5 Renal cell carcinoma; TGCT cis rs1670533 0.932 rs9992925 chr4:1050909 A/T cg27284194 chr4:1044797 NA 0.68 5.87 0.47 3.76e-8 Recombination rate (females); TGCT cis rs11971779 0.648 rs66463279 chr7:139118661 A/G cg07862535 chr7:139043722 LUC7L2 0.66 5.07 0.41 1.42e-6 Diisocyanate-induced asthma; TGCT cis rs4820792 0.725 rs1884816 chr22:29106733 T/C cg03733026 chr22:29445468 ZNRF3 0.25 4.85 0.4 3.67e-6 Breast size; TGCT cis rs4563143 0.675 rs34113156 chr19:29270822 G/A cg04546413 chr19:29218101 NA 0.84 6.76 0.52 4.71e-10 Methadone dose in opioid dependence; TGCT cis rs877282 0.898 rs11253348 chr10:765852 C/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs7822232 0.908 rs6558297 chr8:145143934 C/T cg06239191 chr8:145163136 KIAA1875 -0.88 -6.45 -0.5 2.26e-9 Blood metabolite levels; TGCT cis rs35306767 0.623 rs12354710 chr10:1114020 C/T cg26597838 chr10:835615 NA 0.49 5.12 0.42 1.15e-6 Eosinophil percentage of granulocytes; TGCT cis rs4460629 0.712 rs11264313 chr1:155076505 A/G cg23973274 chr1:155060172 NA -0.26 -4.66 -0.39 8.1e-6 Serum magnesium levels; TGCT cis rs509477 1.000 rs505763 chr18:32558879 G/A cg23791764 chr18:32556832 MAPRE2 0.59 4.83 0.4 3.9e-6 Cerebrospinal fluid AB1-42 levels; TGCT cis rs4808199 0.948 rs7250368 chr19:19452763 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.64 4.75 0.39 5.58e-6 Nonalcoholic fatty liver disease; TGCT cis rs12681288 0.550 rs4272405 chr8:959014 C/G cg04851639 chr8:1020857 NA -0.27 -4.44 -0.37 1.94e-5 Schizophrenia; TGCT cis rs1401999 1.000 rs1402003 chr3:183642879 C/T cg01324343 chr3:183735012 ABCC5 0.82 10.35 0.68 1.81e-18 Anterior chamber depth; TGCT cis rs11577318 0.626 rs11806568 chr1:26686837 C/A cg15090202 chr1:26687087 NA 0.59 4.58 0.38 1.1e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs826838 0.967 rs11169142 chr12:39085773 A/T cg26384229 chr12:38710491 ALG10B -0.85 -8.09 -0.59 4.68e-13 Heart rate; TGCT cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.695 rs10815147 chr9:5016145 C/T cg02405213 chr9:5042618 JAK2 -0.72 -9.2 -0.64 1.06e-15 Pediatric autoimmune diseases; TGCT cis rs2241685 0.850 rs7591787 chr2:1942841 C/T cg21862353 chr2:1801628 MYT1L -0.52 -4.77 -0.39 5.05e-6 Attention deficit hyperactivity disorder; TGCT cis rs9393692 1.000 rs2393593 chr6:26285683 T/C cg00631329 chr6:26305371 NA -0.46 -6.82 -0.52 3.51e-10 Educational attainment; TGCT cis rs1215050 0.791 rs2658477 chr4:98850993 G/A cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.861 rs2065477 chr1:53250213 C/T cg24675658 chr1:53192096 ZYG11B -0.71 -7.99 -0.58 8e-13 Monocyte count; TGCT cis rs9303542 0.571 rs2202895 chr17:46584657 T/C cg25032089 chr17:46643351 HOXB3 -0.52 -5.82 -0.46 4.61e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs4372836 0.897 rs6707130 chr2:28973276 A/G cg09522027 chr2:28974177 PPP1CB -0.6 -5.18 -0.42 8.74e-7 Body mass index; TGCT cis rs12210905 1.000 rs3531 chr6:27095313 T/C cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs4665809 0.590 rs4665840 chr2:26444962 C/T cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs6433857 0.536 rs1971135 chr2:181351508 G/A cg23363182 chr2:181467187 NA -0.32 -4.85 -0.4 3.59e-6 Body mass index; TGCT cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs9818758 0.545 rs9853352 chr3:49813258 C/T cg08550065 chr3:50336684 HYAL3;NAT6 -1.08 -5.44 -0.44 2.72e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg18252515 chr7:66147081 NA -1.2 -7.16 -0.54 6.16e-11 Diabetic kidney disease; TGCT cis rs2153535 0.580 rs1335636 chr6:8465047 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs61990749 0.544 rs1477259 chr14:78256138 C/G cg23188588 chr14:78226832 SNW1;C14orf178 0.64 4.5 0.37 1.54e-5 Fibroblast growth factor basic levels; TGCT cis rs6988636 1.000 rs28624331 chr8:124190768 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT trans rs877282 0.898 rs12357016 chr10:765675 C/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs2233152 0.656 rs10405633 chr19:41291703 G/A cg11601297 chr19:41224147 ITPKC;ADCK4 0.53 4.86 0.4 3.46e-6 Kawasaki disease; TGCT cis rs13394619 0.562 rs34532804 chr2:11746003 G/A cg07314298 chr2:11723111 GREB1 0.29 4.93 0.4 2.59e-6 Endometriosis; TGCT cis rs11673344 0.563 rs4805199 chr19:37606429 A/G cg08039142 chr19:36980659 ZNF566 0.51 4.76 0.39 5.26e-6 Obesity-related traits; TGCT cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg20607798 chr8:58055168 NA 0.45 4.68 0.39 7.47e-6 Developmental language disorder (linguistic errors); TGCT cis rs6460942 0.915 rs2216051 chr7:12304054 G/A cg20607287 chr7:12443886 VWDE -0.47 -4.51 -0.38 1.5e-5 Coronary artery disease; TGCT cis rs6540559 0.673 rs6540564 chr1:210019910 T/C cg22029157 chr1:209979665 IRF6 0.71 5.09 0.42 1.3e-6 Cleft lip with or without cleft palate; TGCT cis rs6901004 0.716 rs35312643 chr6:111574536 C/A cg15721981 chr6:111408429 SLC16A10 0.53 4.61 0.38 9.85e-6 Blood metabolite levels; TGCT cis rs7020830 0.898 rs7038219 chr9:37182892 C/A cg14235030 chr9:37121269 ZCCHC7 0.39 4.47 0.37 1.75e-5 Schizophrenia; TGCT cis rs2153535 0.580 rs9406170 chr6:8514153 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs926938 0.765 rs2268701 chr1:115233046 C/T cg12756093 chr1:115239321 AMPD1 -0.42 -6.03 -0.48 1.72e-8 Autism; TGCT cis rs992157 1.000 rs11554825 chr2:219125809 C/T cg00012203 chr2:219082015 ARPC2 0.77 8.2 0.59 2.56e-13 Colorectal cancer; TGCT cis rs7698623 0.850 rs7678318 chr4:88768888 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs858239 0.600 rs7784929 chr7:23124277 T/C cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT trans rs11722228 0.549 rs55848383 chr4:10081117 C/A cg26043149 chr18:55253948 FECH 1.15 11.34 0.71 6.89e-21 Gout;Urate levels;Serum uric acid levels; TGCT cis rs7666738 0.830 rs11932887 chr4:99072965 C/G cg05340658 chr4:99064831 C4orf37 0.55 6.22 0.49 7.09e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.69 4.91 0.4 2.75e-6 Platelet count; TGCT cis rs9611565 0.512 rs45500192 chr22:42177899 A/G cg03806693 chr22:41940476 POLR3H -1.01 -10.3 -0.68 2.33e-18 Vitiligo; TGCT cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg26531700 chr6:26746687 NA -0.54 -4.87 -0.4 3.36e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs346785 0.692 rs2279052 chr17:74287204 C/G cg09812376 chr17:74270190 QRICH2 -0.37 -5.63 -0.45 1.17e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs7674212 0.570 rs6841136 chr4:104103509 A/C cg16532752 chr4:104119610 CENPE -0.55 -5.09 -0.42 1.32e-6 Type 2 diabetes; TGCT cis rs4494114 0.967 rs9438978 chr1:39355058 G/T cg25970120 chr1:39325951 RRAGC -0.6 -6.31 -0.49 4.61e-9 Blood protein levels; TGCT cis rs7666738 0.830 rs7679299 chr4:99057620 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1215050 0.626 rs1010190 chr4:98585818 A/G cg05340658 chr4:99064831 C4orf37 -0.42 -5.02 -0.41 1.75e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1997103 1.000 rs4948012 chr7:55412578 A/C cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9796 0.870 rs2412574 chr15:41259707 G/C cg18705301 chr15:41695430 NDUFAF1 -0.44 -5.84 -0.46 4.27e-8 Menopause (age at onset); TGCT cis rs861020 0.527 rs614662 chr1:209962419 C/T cg21951975 chr1:209979733 IRF6 -0.45 -4.83 -0.4 3.98e-6 Orofacial clefts; TGCT cis rs61884328 0.777 rs17790420 chr11:47169555 G/A cg13308137 chr11:47528955 CUGBP1 0.38 4.48 0.37 1.65e-5 Total body bone mineral density (age over 60); TGCT cis rs60843830 1.000 rs3791224 chr2:221981 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.77 7.47 0.56 1.22e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1878931 0.501 rs9921169 chr16:3421261 A/T cg22508957 chr16:3507546 NAT15 -0.38 -4.98 -0.41 2.1e-6 Body mass index (adult); TGCT cis rs1008375 1.000 rs6854733 chr4:17640526 C/T cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11190604 1.000 rs57025426 chr10:102205868 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7100689 0.826 rs7098414 chr10:82214586 A/C cg01528321 chr10:82214614 TSPAN14 1.12 12.32 0.74 2.82e-23 Post bronchodilator FEV1; TGCT cis rs9868809 0.505 rs9882549 chr3:48749358 C/T cg00383909 chr3:49044727 WDR6 0.98 5.67 0.45 9.63e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs17102423 0.731 rs7145112 chr14:65534084 A/C cg11161011 chr14:65562177 MAX -0.47 -6.24 -0.49 6.38e-9 Obesity-related traits; TGCT cis rs2718798 1 rs2718798 chr3:133492088 A/C cg16414030 chr3:133502952 NA -0.45 -6.27 -0.49 5.39e-9 Ankle injury; TGCT cis rs2354432 1.000 rs6680778 chr1:146747153 T/C cg25205988 chr1:146714368 CHD1L 1.4 12.0 0.73 1.76e-22 Mitochondrial DNA levels; TGCT cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg06481639 chr22:41940642 POLR3H -0.75 -6.47 -0.5 2.1e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs55665837 0.524 rs61884009 chr11:14426462 C/T cg19336497 chr11:14380999 RRAS2 -0.31 -4.85 -0.4 3.57e-6 Vitamin D levels; TGCT cis rs72627509 0.857 rs2227901 chr4:57798189 A/G cg26694713 chr4:57773883 REST -0.72 -6.33 -0.49 4.07e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2404618 0.561 rs4242536 chr8:1477225 A/G cg13402656 chr8:1511478 DLGAP2 -0.34 -5.68 -0.45 9.12e-8 Lung cancer; TGCT cis rs7523050 0.643 rs35924015 chr1:109404626 T/C cg08274380 chr1:109419600 GPSM2 1.15 5.85 0.47 4.11e-8 Fat distribution (HIV); TGCT cis rs3820068 0.524 rs34094056 chr1:15824154 G/T cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs3733585 0.673 rs4311316 chr4:9955971 A/C cg00071950 chr4:10020882 SLC2A9 0.56 6.73 0.52 5.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9291683 0.620 rs4383618 chr4:10125151 T/C cg11266682 chr4:10021025 SLC2A9 -0.45 -5.32 -0.43 4.65e-7 Bone mineral density; TGCT cis rs4803468 0.967 rs284661 chr19:41932120 C/T cg09537434 chr19:41945824 ATP5SL -0.92 -10.44 -0.68 1.1e-18 Height; TGCT cis rs1218582 0.772 rs6699043 chr1:154913021 T/C cg24250549 chr1:154909240 PMVK 0.62 6.28 0.49 5.29e-9 Prostate cancer; TGCT cis rs2303745 0.544 rs12710308 chr19:17395879 T/A cg02221750 chr19:17393354 ANKLE1 -0.48 -6.28 -0.49 5.17e-9 Systemic lupus erythematosus; TGCT trans rs656319 0.591 rs17734690 chr8:9713196 T/C cg15556689 chr8:8085844 FLJ10661 -0.71 -6.99 -0.53 1.51e-10 Myopia (pathological); TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg08859206 chr1:53392774 SCP2 -0.43 -6.56 -0.51 1.31e-9 Monocyte count; TGCT cis rs4285028 0.699 rs2689285 chr3:121586486 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.78 6.72 0.52 5.95e-10 Multiple sclerosis; TGCT cis rs11190604 1.000 rs2489046 chr10:102346282 A/C cg23241863 chr10:102295624 HIF1AN 0.71 5.43 0.44 2.82e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7605378 0.528 rs281767 chr2:200823281 C/A cg19045956 chr2:200819837 C2orf60;C2orf47 0.54 5.82 0.46 4.81e-8 Osteoporosis; TGCT cis rs9303401 0.573 rs34097494 chr17:57171917 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs17681684 0.565 rs62066034 chr17:9758829 A/G cg15743799 chr17:9805578 RCVRN -0.27 -5.9 -0.47 3.19e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs7726839 0.540 rs72703080 chr5:595238 A/G cg16624210 chr5:671434 TPPP 0.45 4.92 0.4 2.71e-6 Obesity-related traits; TGCT cis rs10875746 0.669 rs11168516 chr12:48702065 C/T cg20731937 chr12:48336164 NA 0.61 4.63 0.38 9.26e-6 Longevity (90 years and older); TGCT cis rs11711311 0.747 rs11928590 chr3:113343478 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -5.88 -0.47 3.5e-8 IgG glycosylation; TGCT cis rs35771425 0.619 rs7529900 chr1:211442661 C/T cg25617285 chr1:211431773 RCOR3 -0.48 -5.48 -0.44 2.27e-7 Educational attainment (years of education); TGCT cis rs6835098 1.000 rs6826412 chr4:174109622 C/T cg08422745 chr4:174089978 GALNT7 -0.9 -10.08 -0.67 7.91e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7172809 0.573 rs8035526 chr15:77683247 T/G cg22256960 chr15:77711686 NA -0.5 -4.74 -0.39 5.82e-6 Glucose homeostasis traits; TGCT cis rs875971 0.666 rs13242072 chr7:65765988 A/G cg18876405 chr7:65276391 NA -0.4 -6.11 -0.48 1.2e-8 Aortic root size; TGCT cis rs68170813 0.559 rs78079372 chr7:106934548 T/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT trans rs986417 0.818 rs761557 chr14:61077484 C/T cg06338710 chr1:92946187 GFI1 0.73 7.02 0.53 1.3100000000000001e-10 Gut microbiota (bacterial taxa); TGCT cis rs17221829 0.610 rs1844195 chr11:89389332 G/A cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT trans rs28595532 0.516 rs28552458 chr4:119288363 T/C cg26518628 chr1:97050305 NA -0.6 -7.07 -0.54 1.01e-10 Cannabis dependence symptom count; TGCT cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg08645402 chr16:4508243 NA 0.2 5.01 0.41 1.86e-6 Schizophrenia; TGCT cis rs35306767 0.579 rs7091502 chr10:1154979 C/T cg20503657 chr10:835505 NA 0.54 5.8 0.46 5.25e-8 Eosinophil percentage of granulocytes; TGCT cis rs9814567 0.752 rs6779294 chr3:134329821 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg04317338 chr11:64019027 PLCB3 0.74 6.01 0.48 1.89e-8 Mean platelet volume; TGCT cis rs2836950 0.545 rs8132424 chr21:40584412 A/T cg17971929 chr21:40555470 PSMG1 0.52 4.74 0.39 5.74e-6 Menarche (age at onset); TGCT cis rs7523050 0.643 rs7551313 chr1:109399881 G/A cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs514406 0.505 rs425520 chr1:53179805 C/G cg16325326 chr1:53192061 ZYG11B 0.85 12.13 0.74 8.13e-23 Monocyte count; TGCT cis rs10193935 0.582 rs13394853 chr2:42630900 T/C cg27598129 chr2:42591480 NA -0.37 -5.23 -0.42 7.1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4888262 0.508 rs12598701 chr16:74539904 G/A cg01733217 chr16:74700730 RFWD3 0.68 6.88 0.53 2.6200000000000003e-10 Testicular germ cell tumor; TGCT cis rs752092 0.802 rs2412005 chr15:101767591 T/A cg19997662 chr15:101784653 CHSY1 -0.27 -5.0 -0.41 1.9e-6 Corneal structure; TGCT cis rs1862618 0.853 rs832568 chr5:56153776 G/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs35883536 1.000 rs2297712 chr1:101092813 C/T cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.19e-5 Monocyte count; TGCT cis rs8031584 0.678 rs4779497 chr15:31151365 T/A cg14829155 chr15:31115871 NA -0.36 -4.72 -0.39 6.14e-6 Huntington's disease progression; TGCT cis rs763014 0.898 rs916416 chr16:632198 T/A cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs7655441 1.000 rs7686031 chr4:80908268 T/C cg02241357 chr4:80885279 ANTXR2 -0.24 -4.59 -0.38 1.07e-5 Neutrophil percentage of white cells; TGCT cis rs1799949 0.930 rs34210004 chr17:41370337 A/T cg10047753 chr17:41438598 NA 0.7 6.5 0.5 1.75e-9 Menopause (age at onset); TGCT cis rs2197308 0.765 rs117216293 chr12:37882982 T/C cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs9325144 0.505 rs7138977 chr12:38642109 G/A cg13010199 chr12:38710504 ALG10B 0.62 5.54 0.45 1.71e-7 Morning vs. evening chronotype; TGCT cis rs2730245 0.527 rs62476462 chr7:158686619 A/G cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs11148252 0.574 rs61958118 chr13:53170226 C/T cg00495681 chr13:53174319 NA 0.7 7.09 0.54 9.05e-11 Lewy body disease; TGCT cis rs10876993 0.928 rs1689594 chr12:58057156 T/C cg15848620 chr12:58087721 OS9 -0.72 -5.86 -0.47 3.95e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs2956278 0.717 rs2956285 chr12:84690194 C/T cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg12667521 chr19:29218732 NA 0.54 5.72 0.46 7.65e-8 Methadone dose in opioid dependence; TGCT cis rs6988636 0.818 rs1713733 chr8:124199458 A/G cg23067535 chr8:124195133 FAM83A 0.32 4.82 0.4 4.11e-6 Urinary uromodulin levels; TGCT cis rs6460942 1.000 rs112996286 chr7:12315741 G/C cg06484146 chr7:12443880 VWDE -0.55 -4.56 -0.38 1.22e-5 Coronary artery disease; TGCT cis rs12540874 0.728 rs3807563 chr7:50566390 C/T cg18232548 chr7:50535776 DDC -0.37 -6.48 -0.5 1.97e-9 Systemic sclerosis; TGCT cis rs796364 0.760 rs2202922 chr2:200882610 C/T cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT cis rs2153535 0.580 rs1577466 chr6:8444192 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs4455778 0.538 rs7795732 chr7:49127493 T/C cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs57920188 0.584 rs12068729 chr1:4091650 A/G cg20703997 chr1:4087676 NA 0.49 6.2 0.49 7.57e-9 Interleukin-17 levels; TGCT cis rs7586879 0.575 rs6712981 chr2:25126230 A/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs9549367 0.756 rs9549702 chr13:113881944 T/G cg18105134 chr13:113819100 PROZ -0.34 -5.67 -0.45 9.36e-8 Platelet distribution width; TGCT cis rs7618915 0.501 rs3733041 chr3:52731598 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.09 -0.42 1.27e-6 Bipolar disorder; TGCT cis rs12477438 1.000 rs12477438 chr2:99841085 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -6.39 -0.5 2.97e-9 Chronic sinus infection; TGCT cis rs4688759 0.719 rs73079018 chr3:49875327 T/C cg08550065 chr3:50336684 HYAL3;NAT6 1.04 5.12 0.42 1.13e-6 Blood protein levels; TGCT cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg08280861 chr8:58055591 NA 0.39 4.76 0.39 5.35e-6 Developmental language disorder (linguistic errors); TGCT cis rs9348739 1 rs9348739 chr6:26923099 G/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.57 -4.71 -0.39 6.52e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9467711 0.606 rs9358930 chr6:26357011 C/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs10479542 0.896 rs10078712 chr5:178978805 C/T cg00080972 chr5:178986291 RUFY1 -0.44 -5.03 -0.41 1.65e-6 Lung cancer; TGCT trans rs8073060 0.586 rs17638867 chr17:34052513 C/T cg19694781 chr19:47549865 TMEM160 0.6 13.38 0.77 8.17e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2229238 0.911 rs59239860 chr1:154492107 G/T cg13067139 chr1:155221277 FAM189B 0.2 4.49 0.37 1.63e-5 Coronary heart disease; TGCT cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg13732083 chr21:47605072 C21orf56 0.34 4.59 0.38 1.05e-5 Testicular germ cell tumor; TGCT cis rs116095464 0.558 rs9312956 chr5:201812 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.73 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs7226408 0.790 rs58099133 chr18:34332333 C/T cg06757138 chr18:34340585 FHOD3 0.29 4.95 0.41 2.4e-6 Obesity-related traits; TGCT cis rs377070 1.000 rs377070 chr4:123629002 G/C cg10495464 chr4:123653540 BBS12;LOC729338 0.47 5.1 0.42 1.23e-6 Mosquito bite size; TGCT cis rs10927875 0.562 rs10803401 chr1:16147377 G/A cg21385522 chr1:16154831 NA -1.0 -17.61 -0.85 1.57e-35 Dilated cardiomyopathy; TGCT cis rs317689 0.690 rs317656 chr12:69681101 T/A cg14784868 chr12:69753453 YEATS4 0.55 4.76 0.39 5.2e-6 Response to diuretic therapy; TGCT cis rs8051431 0.876 rs8053841 chr16:72012072 C/T cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs909002 0.759 rs10914454 chr1:32078940 G/A cg11573219 chr1:32083031 HCRTR1 -0.44 -5.58 -0.45 1.46e-7 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.572 rs3846846 chr6:26445039 A/G cg15659132 chr6:26577336 NA -0.43 -4.51 -0.38 1.47e-5 Intelligence (multi-trait analysis); TGCT cis rs5769765 0.908 rs138891 chr22:50227741 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.04 -10.95 -0.7 6.06e-20 Schizophrenia; TGCT cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg17054783 chr10:134559939 INPP5A 0.23 4.69 0.39 7.22e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs67072384 1.000 rs67075228 chr11:72450775 C/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs7000551 0.556 rs35359294 chr8:22249755 G/A cg12081754 chr8:22256438 SLC39A14 0.33 4.77 0.39 5.06e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4654899 0.931 rs12723255 chr1:21233570 C/T cg01072550 chr1:21505969 NA 0.51 8.18 0.59 2.84e-13 Superior frontal gyrus grey matter volume; TGCT cis rs9300255 0.544 rs1716174 chr12:123660717 T/C cg00376283 chr12:123451042 ABCB9 0.74 5.1 0.42 1.22e-6 Neutrophil percentage of white cells; TGCT cis rs2455799 0.613 rs1976479 chr3:15729714 C/G cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.65e-6 Mean platelet volume; TGCT cis rs593982 0.920 rs1108922 chr11:65423930 C/T cg08755490 chr11:65554678 OVOL1 -1.15 -6.32 -0.49 4.28e-9 Atopic dermatitis; TGCT cis rs7666738 0.830 rs34671152 chr4:98978177 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs1577917 0.771 rs12205013 chr6:86333029 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs314370 0.904 rs13244629 chr7:100509253 A/C cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs6089584 1.000 rs6142910 chr20:60562181 C/A cg06108461 chr20:60628389 TAF4 -0.57 -8.01 -0.58 7.25e-13 Body mass index; TGCT cis rs1334894 0.892 rs72911394 chr6:35525164 T/C cg24281267 chr6:35479648 TULP1 -0.43 -4.54 -0.38 1.34e-5 Coronary artery disease; TGCT cis rs9311474 0.597 rs6778735 chr3:52565100 T/C cg10802521 chr3:52805072 NEK4 -0.64 -7.66 -0.57 4.56e-12 Electroencephalogram traits; TGCT cis rs3741151 1.000 rs76887714 chr11:73045500 C/T cg17517138 chr11:73019481 ARHGEF17 1.01 5.08 0.42 1.34e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs72781680 0.679 rs718138 chr2:23976324 G/A cg08917208 chr2:24149416 ATAD2B 0.75 5.04 0.41 1.59e-6 Lymphocyte counts; TGCT cis rs12477438 0.501 rs12995473 chr2:99764884 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.13 0.63 1.6e-15 Cognitive function; TGCT cis rs9296092 0.517 rs56206922 chr6:33522567 C/T cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs508618 0.697 rs7534248 chr1:231554531 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.62 5.11 0.42 1.18e-6 Red blood cell count; TGCT cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg17554472 chr22:41940697 POLR3H -0.48 -4.95 -0.41 2.39e-6 Vitiligo; TGCT cis rs12142240 0.698 rs6696777 chr1:46810970 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs651907 0.535 rs13094911 chr3:101519021 T/C cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs1401999 1.000 rs1401999 chr3:183678342 C/G cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs9427116 0.702 rs9427108 chr1:154607914 G/A cg17218026 chr1:154582156 ADAR 0.28 7.02 0.53 1.3e-10 Blood protein levels; TGCT cis rs1448094 0.511 rs10863083 chr12:86226739 C/A cg02569458 chr12:86230093 RASSF9 0.36 4.53 0.38 1.36e-5 Major depressive disorder; TGCT cis rs6893807 0.778 rs13173305 chr5:87945377 A/G cg24804195 chr5:87968844 LOC645323 0.78 4.57 0.38 1.14e-5 Body mass index; TGCT cis rs4478858 0.735 rs1566963 chr1:31772206 G/A cg00250761 chr1:31883323 NA -0.28 -5.01 -0.41 1.86e-6 Alcohol dependence; TGCT cis rs524281 0.817 rs7115081 chr11:65853541 A/G cg00563793 chr11:65837595 PACS1 0.55 4.62 0.38 9.44e-6 Electroencephalogram traits; TGCT cis rs6912958 0.559 rs445434 chr6:88041849 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.45 5.88 0.47 3.49e-8 Monocyte percentage of white cells; TGCT cis rs208520 0.802 rs208499 chr6:66932146 C/T cg07460842 chr6:66804631 NA -0.9 -9.15 -0.63 1.45e-15 Exhaled nitric oxide output; TGCT cis rs644799 1.000 rs580255 chr11:95577929 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.11 0.59 4.26e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3784262 0.669 rs3204690 chr15:58246768 A/C cg12031962 chr15:58353849 ALDH1A2 -0.43 -5.97 -0.47 2.3e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg12310025 chr6:25882481 NA -0.83 -8.49 -0.61 5.24e-14 Blood metabolite levels; TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.68e-6 Prudent dietary pattern; TGCT cis rs2016266 0.826 rs61928079 chr12:53741468 T/C cg16917193 chr12:54089295 NA -0.7 -4.68 -0.39 7.49e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs9914544 0.545 rs7222748 chr17:18787976 T/C cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs12477438 0.520 rs4340581 chr2:99725025 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.0 0.63 3.26e-15 Chronic sinus infection; TGCT cis rs2338224 1.000 rs4703887 chr5:71746038 C/T cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs3617 0.573 rs9880978 chr3:52923251 C/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.86 -0.4 3.44e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs12681287 0.640 rs10086340 chr8:87446789 G/T cg19078186 chr8:87526527 CPNE3 -0.34 -4.55 -0.38 1.26e-5 Caudate activity during reward; TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg01802117 chr1:53393560 SCP2 -0.42 -5.25 -0.43 6.33e-7 Monocyte count; TGCT cis rs17387100 0.901 rs73230220 chr4:15982382 G/A cg14577840 chr4:16257979 FLJ39653 0.5 4.85 0.4 3.56e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs3809566 0.676 rs9806544 chr15:63328360 G/A cg00520135 chr15:63333846 TPM1 -0.4 -4.92 -0.4 2.68e-6 Platelet count; TGCT cis rs12142240 0.698 rs77185326 chr1:46818417 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs79387448 0.745 rs75644281 chr2:103151316 A/T cg09003973 chr2:102972529 NA 0.97 6.32 0.49 4.33e-9 Gut microbiota (bacterial taxa); TGCT cis rs147649347 1 rs147649347 chr2:24210076 GATAA/G cg08917208 chr2:24149416 ATAD2B 0.79 4.78 0.39 4.83e-6 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs453301 0.653 rs7853 chr8:8890814 A/G cg00184457 chr8:8946301 NA 0.24 4.49 0.37 1.64e-5 Joint mobility (Beighton score); TGCT cis rs13191362 0.935 rs66962088 chr6:162963891 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.17e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs5769765 0.913 rs2319462 chr22:50263370 C/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs727563 0.565 rs132774 chr22:42031953 C/G cg06481639 chr22:41940642 POLR3H -0.6 -5.25 -0.43 6.35e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs4443295 chr4:99044935 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2172802 0.693 rs7660566 chr4:62481231 G/T cg04118610 chr4:62707027 LPHN3 0.46 4.96 0.41 2.3e-6 Partial epilepsies; TGCT cis rs778371 0.723 rs6710294 chr2:233579634 T/C cg08000102 chr2:233561755 GIGYF2 0.75 8.99 0.63 3.42e-15 Schizophrenia; TGCT cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg07507251 chr3:52567010 NT5DC2 0.42 5.92 0.47 2.94e-8 Bipolar disorder; TGCT cis rs877282 1.000 rs11253362 chr10:770979 G/T cg17470449 chr10:769945 NA 0.34 5.4 0.44 3.34e-7 Uric acid levels; TGCT cis rs17030434 0.871 rs78151744 chr4:154730266 C/T cg14289246 chr4:154710475 SFRP2 -0.9 -7.58 -0.56 7.16e-12 Electrocardiographic conduction measures; TGCT trans rs629535 0.821 rs660144 chr8:70035629 T/C cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs10791323 0.511 rs4937837 chr11:133731134 T/C cg03690763 chr11:133734501 NA -0.3 -4.53 -0.38 1.38e-5 Childhood ear infection; TGCT cis rs559928 0.553 rs1320628 chr11:64175986 C/T cg12453748 chr11:64085041 PRDX5;TRMT112 0.56 4.85 0.4 3.6e-6 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs801193 0.805 rs12532355 chr7:66070584 C/G cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs10197940 0.510 rs7602715 chr2:152421937 A/G cg19508488 chr2:152266495 RIF1 0.62 5.48 0.44 2.27e-7 Lung cancer; TGCT cis rs8072100 0.840 rs9893901 chr17:45506682 T/G cg08085267 chr17:45401833 C17orf57 -0.5 -5.51 -0.44 2.02e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1218582 0.682 rs12046459 chr1:154912017 A/C cg06221963 chr1:154839813 KCNN3 -0.74 -12.65 -0.75 4.56e-24 Prostate cancer; TGCT cis rs8038465 0.874 rs11574488 chr15:73999379 T/A cg15420318 chr15:73925796 NPTN 0.57 5.12 0.42 1.12e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9926296 0.715 rs467035 chr16:89740285 C/G cg27121462 chr16:89883253 FANCA 0.52 4.96 0.41 2.25e-6 Vitiligo; TGCT cis rs7246657 0.882 rs8112610 chr19:37928730 C/A cg18154014 chr19:37997991 ZNF793 0.73 5.4 0.44 3.23e-7 Coronary artery calcification; TGCT cis rs17076896 0.786 rs74038130 chr13:19933634 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs9926296 0.744 rs164748 chr16:89708292 C/G cg04287289 chr16:89883240 FANCA -0.5 -4.79 -0.39 4.73e-6 Vitiligo; TGCT cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -1.0 -10.76 -0.69 1.79e-19 Height; TGCT cis rs860554 0.546 rs2239845 chr1:201292488 C/T cg01022117 chr1:201258280 PKP1 -0.28 -4.96 -0.41 2.28e-6 Panic disorder; TGCT cis rs72634258 0.554 rs34020118 chr1:7895015 C/T cg26816564 chr1:7831052 VAMP3 0.88 6.53 0.51 1.52e-9 Inflammatory bowel disease; TGCT cis rs10479542 0.642 rs6879665 chr5:178974581 T/A cg14851468 chr5:179071604 C5orf60 0.25 4.86 0.4 3.46e-6 Lung cancer; TGCT cis rs7666738 0.800 rs12163918 chr4:98835794 T/C cg17366294 chr4:99064904 C4orf37 0.72 7.47 0.56 1.23e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12413816 0.963 rs12359348 chr10:13765950 C/T cg16485048 chr10:13749193 FRMD4A -0.25 -5.03 -0.41 1.64e-6 Red cell distribution width; TGCT cis rs12765878 1.000 rs11191848 chr10:105650837 T/C cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs950776 0.647 rs495956 chr15:78869930 C/T cg06917634 chr15:78832804 PSMA4 -0.66 -5.29 -0.43 5.47e-7 Sudden cardiac arrest; TGCT cis rs2458413 0.500 rs2251930 chr8:105357764 G/A cg04554929 chr8:105342491 NA 0.49 5.84 0.46 4.26e-8 Paget's disease; TGCT cis rs10876993 0.784 rs1871417 chr12:58018979 C/T cg15848620 chr12:58087721 OS9 0.72 5.38 0.44 3.52e-7 Celiac disease or Rheumatoid arthritis; TGCT cis rs748404 0.578 rs478028 chr15:43610772 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.46e-6 Lung cancer; TGCT cis rs11122272 0.735 rs11122280 chr1:231519816 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs2637266 1.000 rs7475638 chr10:78358586 G/T cg18941641 chr10:78392320 NA -0.37 -4.67 -0.39 7.71e-6 Pulmonary function; TGCT cis rs9291683 0.595 rs3733585 chr4:10036339 A/G cg11266682 chr4:10021025 SLC2A9 0.64 8.92 0.63 5e-15 Bone mineral density; TGCT cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg19318889 chr4:1322082 MAEA -0.16 -4.46 -0.37 1.84e-5 Obesity-related traits; TGCT cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs797680 0.820 rs10874773 chr1:93798496 T/G cg17826107 chr1:92977322 EVI5 -0.23 -5.14 -0.42 1.05e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs713587 0.607 rs6725517 chr2:25129473 A/G cg01884057 chr2:25150051 NA 0.34 6.57 0.51 1.24e-9 Body mass index in non-asthmatics; TGCT cis rs9467711 0.606 rs9379855 chr6:26364930 C/T cg10795676 chr6:26370623 BTN3A2 0.46 4.75 0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7104764 0.957 rs6598071 chr11:219800 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.05 10.74 0.69 2e-19 Menarche (age at onset); TGCT cis rs6570726 0.791 rs9403730 chr6:145907233 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs875971 1.000 rs6460296 chr7:65895139 C/T cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.12e-6 Aortic root size; TGCT cis rs950169 1.000 rs11638394 chr15:84778928 G/A cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.07e-8 Schizophrenia; TGCT cis rs11874712 1.000 rs9944637 chr18:43655239 G/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.04e-7 Migraine - clinic-based; TGCT cis rs151997 0.777 rs6870880 chr5:50256207 G/A cg06027927 chr5:50259733 NA 0.56 5.92 0.47 2.88e-8 Callous-unemotional behaviour; TGCT cis rs9926296 0.605 rs12599180 chr16:89839306 C/T cg03388025 chr16:89894329 SPIRE2 -0.46 -7.98 -0.58 8.26e-13 Vitiligo; TGCT cis rs459571 0.959 rs465724 chr9:136910097 C/T cg13789015 chr9:136890014 NCRNA00094 0.4 7.28 0.55 3.41e-11 Platelet distribution width; TGCT cis rs7359276 1 rs7359276 chr15:78892661 C/T cg24631222 chr15:78858424 CHRNA5 -0.8 -5.84 -0.46 4.29e-8 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7044106 0.762 rs7044226 chr9:123466328 G/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.7 0.39 6.66e-6 Hip circumference adjusted for BMI; TGCT trans rs77457752 0.525 rs10120720 chr9:13897929 G/C cg23609682 chr1:3070786 PRDM16 0.5 6.79 0.52 4.09e-10 Breast cancer; TGCT cis rs7666738 0.830 rs11944855 chr4:99068258 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs8067545 1.000 rs4925066 chr17:19915292 A/G cg13482628 chr17:19912719 NA 0.55 4.83 0.4 3.98e-6 Schizophrenia; TGCT cis rs651907 1.000 rs665211 chr3:101600028 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.47 4.8 0.4 4.46e-6 Colorectal cancer; TGCT cis rs9372498 0.536 rs62422227 chr6:118957200 C/G cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.69 0.62 1.83e-14 Platelet count; TGCT cis rs9534288 0.762 rs9534292 chr13:46611340 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs79149102 0.579 rs61166993 chr15:75306644 C/A cg09165964 chr15:75287851 SCAMP5 -1.04 -5.73 -0.46 7.2e-8 Lung cancer; TGCT cis rs4629710 0.592 rs67399092 chr6:131582936 G/A cg12606694 chr6:131520996 AKAP7 0.4 4.77 0.39 5.05e-6 Multiple myeloma (IgH translocation); TGCT cis rs187455071 1 rs187455071 chr4:106805884 A/G cg24545054 chr4:106630052 GSTCD;INTS12 1.01 4.61 0.38 9.71e-6 Post bronchodilator FEV1; TGCT cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9549367 0.713 rs2146750 chr13:113822530 A/G cg00898013 chr13:113819073 PROZ 0.4 4.58 0.38 1.12e-5 Platelet distribution width; TGCT cis rs6671200 0.573 rs6666528 chr1:95697490 C/A cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs12615966 0.651 rs72830470 chr2:105406694 C/T cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg10108389 chr3:44770937 ZNF501 -0.47 -4.87 -0.4 3.34e-6 Depressive symptoms; TGCT cis rs7647973 0.769 rs7434187 chr3:49032967 C/T cg07636037 chr3:49044803 WDR6 0.82 6.59 0.51 1.12e-9 Menarche (age at onset); TGCT cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg17554472 chr22:41940697 POLR3H -0.51 -5.5 -0.44 2.09e-7 Vitiligo; TGCT cis rs2067615 0.579 rs10861667 chr12:107194776 T/G cg15890332 chr12:107067104 RFX4 0.28 5.53 0.44 1.8e-7 Heart rate; TGCT cis rs6582630 0.533 rs2120464 chr12:38280289 A/C cg26384229 chr12:38710491 ALG10B 0.53 4.67 0.39 7.65e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7523050 0.643 rs71655970 chr1:109403895 A/G cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs780096 0.526 rs1406295 chr2:27689700 A/G cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT cis rs9500256 0.934 rs1343391 chr6:58344154 C/G cg16251399 chr6:58287822 GUSBL2 0.63 5.75 0.46 6.49e-8 Eosinophilic esophagitis (pediatric); TGCT cis rs11031096 0.769 rs12803541 chr11:4208906 G/A cg18678763 chr11:4115507 RRM1 0.4 5.19 0.42 8.27e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT trans rs1814175 0.715 rs10839409 chr11:49884647 G/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs933688 1.000 rs12188467 chr5:90765632 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.87 8.03 0.58 6.54e-13 Smoking behavior; TGCT trans rs7726839 0.540 rs4957081 chr5:646418 G/C cg25482853 chr8:67687455 SGK3 1.19 10.3 0.68 2.4e-18 Obesity-related traits; TGCT cis rs67478160 0.634 rs7141928 chr14:104219949 C/T cg26031613 chr14:104095156 KLC1 -0.64 -6.49 -0.5 1.89e-9 Schizophrenia; TGCT cis rs975739 0.669 rs7986312 chr13:78584793 T/G cg07847733 chr13:78271382 SLAIN1 0.5 4.44 0.37 1.96e-5 Hair color; TGCT cis rs1997103 1.000 rs6949244 chr7:55411301 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2677744 0.626 rs11207 chr15:91497239 C/T cg22570213 chr15:91497863 RCCD1 0.41 4.96 0.41 2.24e-6 Attention deficit hyperactivity disorder; TGCT cis rs77633900 0.614 rs280029 chr15:77031235 A/G cg21673338 chr15:77095150 SCAPER -0.53 -5.22 -0.42 7.33e-7 Non-glioblastoma glioma;Glioma; TGCT cis rs7412746 0.611 rs7532045 chr1:150821847 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.69 0.39 7.24e-6 Melanoma; TGCT cis rs2456568 0.900 rs1518571 chr11:93667420 C/A cg26875233 chr11:93583750 C11orf90 -0.45 -5.61 -0.45 1.27e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7267979 0.816 rs376742 chr20:25487417 A/C cg14121845 chr20:25566513 NINL 0.45 4.69 0.39 7.14e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9381040 1.000 rs2093395 chr6:41155026 C/G cg03526776 chr6:41159608 TREML2 -0.34 -6.94 -0.53 1.92e-10 Alzheimer's disease (late onset); TGCT cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.84 0.4 3.86e-6 Platelet count; TGCT cis rs7845219 0.597 rs7002058 chr8:95873993 G/C cg16049864 chr8:95962084 TP53INP1 -0.55 -6.29 -0.49 4.98e-9 Type 2 diabetes; TGCT cis rs7666738 0.791 rs6833691 chr4:98951508 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7714584 1.000 rs4958842 chr5:150224877 G/A cg22134413 chr5:150180641 NA 1.12 8.12 0.59 3.99e-13 Crohn's disease; TGCT cis rs595982 0.501 rs112370206 chr19:49396623 C/T cg11637076 chr19:49575188 KCNA7 -0.44 -5.23 -0.43 6.99e-7 Red cell distribution width; TGCT cis rs6121246 0.821 rs6121209 chr20:30311258 G/C cg13852791 chr20:30311386 BCL2L1 0.81 6.27 0.49 5.38e-9 Mean corpuscular hemoglobin; TGCT cis rs587847 0.737 rs28373878 chr15:37664826 G/A cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs11096990 0.656 rs6531709 chr4:39302249 T/G cg20847110 chr4:39482781 LOC401127 -0.16 -4.52 -0.38 1.43e-5 Cognitive function; TGCT cis rs1994135 0.565 rs11052767 chr12:33731194 A/G cg06521331 chr12:34319734 NA -0.31 -4.79 -0.4 4.71e-6 Resting heart rate; TGCT cis rs7726839 0.540 rs4957083 chr5:659343 T/C cg16624210 chr5:671434 TPPP 0.41 4.6 0.38 1.02e-5 Obesity-related traits; TGCT cis rs600231 0.708 rs682845 chr11:65254201 A/G cg17120908 chr11:65337727 SSSCA1 -0.57 -5.39 -0.44 3.46e-7 Bone mineral density; TGCT cis rs2070488 1.000 rs6772046 chr3:38479660 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.92 9.68 0.66 7.36e-17 Electrocardiographic conduction measures; TGCT cis rs7208859 0.673 rs17826219 chr17:29161845 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs1814175 0.727 rs2140597 chr11:49873946 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs1669338 0.588 rs3749360 chr3:3213775 G/A cg16797762 chr3:3221439 CRBN -0.92 -5.82 -0.46 4.76e-8 White matter integrity; TGCT cis rs7208859 0.673 rs73277967 chr17:29184166 T/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9611519 0.780 rs1983631 chr22:41644074 C/T cg06634786 chr22:41940651 POLR3H -0.54 -4.83 -0.4 3.87e-6 Neuroticism; TGCT cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs4776059 0.958 rs35505902 chr15:52888493 A/G cg25063058 chr15:52860530 ARPP19 0.52 4.71 0.39 6.66e-6 Schizophrenia; TGCT cis rs7659604 0.502 rs10212738 chr4:122675724 G/A cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs1218582 0.741 rs11264291 chr1:154914797 C/T cg06221963 chr1:154839813 KCNN3 -0.71 -11.94 -0.73 2.43e-22 Prostate cancer; TGCT cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg13607699 chr17:42295918 UBTF -0.73 -7.05 -0.53 1.1e-10 Total body bone mineral density; TGCT cis rs2242116 0.796 rs4683296 chr3:46973820 G/C cg27129171 chr3:47204927 SETD2 -0.65 -6.37 -0.5 3.28e-9 Birth weight; TGCT cis rs6141769 0.518 rs6057631 chr20:31319149 A/G cg13636640 chr20:31349939 DNMT3B -0.52 -4.55 -0.38 1.26e-5 Subjective well-being; TGCT cis rs9303401 0.659 rs12935851 chr17:56600244 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs11578119 0.898 rs6427253 chr1:170433401 C/T cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs17331151 0.505 rs35225119 chr3:52623465 A/T cg24616795 chr3:53032891 SFMBT1 0.6 4.9 0.4 2.97e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9796 0.621 rs9972349 chr15:41491656 A/G cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.18 -0.54 5.68e-11 Menopause (age at onset); TGCT cis rs2180341 1.000 rs2038378 chr6:127590400 C/T cg24812749 chr6:127587940 RNF146 0.97 7.52 0.56 9.68e-12 Breast cancer; TGCT cis rs7772486 0.754 rs6906258 chr6:146089356 A/G cg05347473 chr6:146136440 FBXO30 -0.53 -5.01 -0.41 1.84e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2562456 0.917 rs2650793 chr19:21676115 C/G cg01304269 chr19:21688519 ZNF429 -0.59 -5.04 -0.41 1.64e-6 Pain; TGCT cis rs13064411 0.696 rs6773497 chr3:113186514 T/C cg18753928 chr3:113234510 CCDC52 -0.69 -5.57 -0.45 1.47e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2073300 1.000 rs6048827 chr20:23458080 T/C cg09953122 chr20:23471693 CST8 -0.6 -4.72 -0.39 6.22e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs4689388 0.853 rs13114527 chr4:6294655 T/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9302001 0.920 rs6492751 chr13:95460383 C/T cg07483244 chr13:95358924 NA 0.37 4.79 0.4 4.65e-6 Panic disorder; TGCT cis rs1475911 0.708 rs56109792 chr21:43520060 A/G cg24372256 chr21:43528868 UMODL1;C21orf128 -0.31 -5.88 -0.47 3.64e-8 IgG glycosylation; TGCT cis rs9952991 0.709 rs71353225 chr18:12759183 T/C cg23598886 chr18:12777645 NA -0.65 -4.66 -0.39 8.08e-6 Inflammatory skin disease; TGCT cis rs79057730 0.527 rs34519158 chr7:811114 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.65 6.07 0.48 1.41e-8 Initial pursuit acceleration; TGCT cis rs1480597 0.518 rs1480603 chr10:45197977 G/T cg12063947 chr10:45878068 ALOX5 0.26 4.44 0.37 2e-5 Parkinson's disease; TGCT cis rs6964587 1.000 rs4644173 chr7:91759597 A/G cg22709100 chr7:91322751 NA 0.28 4.46 0.37 1.81e-5 Breast cancer; TGCT cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg19635926 chr16:89946313 TCF25 0.25 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs1023500 0.573 rs13057094 chr22:42470317 T/C cg15557168 chr22:42548783 NA -0.21 -5.27 -0.43 5.81e-7 Schizophrenia; TGCT cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg18230493 chr5:56204884 C5orf35 -0.67 -5.71 -0.46 8e-8 Initial pursuit acceleration; TGCT cis rs9443645 0.901 rs1542977 chr6:79550307 G/T cg09184832 chr6:79620586 NA -0.48 -5.3 -0.43 5.19e-7 Intelligence (multi-trait analysis); TGCT cis rs4851266 0.933 rs6709656 chr2:100806719 A/G cg22139774 chr2:100720529 AFF3 -0.35 -5.29 -0.43 5.24e-7 Educational attainment; TGCT cis rs2115630 1.000 rs2115630 chr15:85364516 C/T cg09876464 chr15:85330779 ZNF592 0.19 4.47 0.37 1.76e-5 P wave terminal force; TGCT cis rs9926296 0.609 rs4785714 chr16:89798404 G/T cg27121462 chr16:89883253 FANCA -0.53 -4.95 -0.41 2.38e-6 Vitiligo; TGCT cis rs875971 0.964 rs778708 chr7:65856319 T/C cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs9354352 0.935 rs7766730 chr6:66697003 C/A cg07460842 chr6:66804631 NA 0.65 6.68 0.51 7.29e-10 Initial pursuit acceleration in psychotic disorders; TGCT cis rs2708977 0.933 rs6576972 chr2:97152446 C/T cg01950434 chr2:97203154 ARID5A -0.72 -6.77 -0.52 4.6e-10 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1215050 0.791 rs1727278 chr4:98853576 A/G cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.18e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg03517284 chr6:25882590 NA 0.78 8.11 0.59 4.26e-13 Blood metabolite levels; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg01577475 chr2:114033581 PAX8;LOC440839 -0.44 -4.75 -0.39 5.42e-6 Lymphocyte counts; TGCT cis rs2228479 0.717 rs11644967 chr16:89806614 T/A cg27121462 chr16:89883253 FANCA 0.78 4.65 0.39 8.51e-6 Skin colour saturation; TGCT cis rs9640161 0.830 rs17173681 chr7:150059414 A/G cg10018233 chr7:150070692 REPIN1 -0.31 -4.62 -0.38 9.57e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs3125734 0.653 rs1007976 chr10:63970144 C/T cg05499367 chr10:63213510 TMEM26 0.34 4.54 0.38 1.32e-5 Rheumatoid arthritis; TGCT cis rs10782582 0.532 rs12132503 chr1:76137762 C/G cg22875332 chr1:76189707 ACADM -0.55 -6.28 -0.49 5.25e-9 Daytime sleep phenotypes; TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg11235426 chr6:292522 DUSP22 -0.68 -6.94 -0.53 1.92e-10 Menopause (age at onset); TGCT cis rs2677744 0.626 rs11207 chr15:91497239 C/T cg23684204 chr15:91497937 RCCD1 0.4 6.12 0.48 1.15e-8 Attention deficit hyperactivity disorder; TGCT cis rs9467773 1.000 rs6933176 chr6:26540178 G/A cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs2980439 0.525 rs1850511 chr8:8170329 T/A cg15556689 chr8:8085844 FLJ10661 0.67 5.79 0.46 5.4e-8 Neuroticism; TGCT cis rs7524258 0.868 rs4908607 chr1:7269323 A/G cg04342483 chr1:7259290 CAMTA1 -0.3 -4.45 -0.37 1.89e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7655841 0.504 rs10028974 chr4:129871442 C/A cg26347359 chr4:129759716 PHF17 0.46 6.16 0.48 9.24e-9 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs9894429 1.000 rs9894429 chr17:79596811 C/T cg18240062 chr17:79603768 NPLOC4 0.69 7.22 0.54 4.67e-11 Eye color traits; TGCT cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg12310025 chr6:25882481 NA -0.59 -6.04 -0.48 1.65e-8 Blood metabolite levels; TGCT cis rs8141529 0.719 rs9625619 chr22:29272328 T/A cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs2806561 0.695 rs67238799 chr1:23335012 G/A cg12483005 chr1:23474871 LUZP1 0.37 4.72 0.39 6.21e-6 Height; TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs71718386 1 rs71718386 chr13:41224287 CTATA/C cg21288729 chr13:41239152 FOXO1 1.01 10.71 0.69 2.36e-19 Eosinophil counts; TGCT cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -6.22 -0.49 6.97e-9 Type 2 diabetes; TGCT cis rs7772486 0.686 rs9497380 chr6:145955305 T/C cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.35e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs11122272 0.603 rs2998427 chr1:231528112 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -6.12 -0.48 1.12e-8 Hemoglobin concentration; TGCT cis rs17767294 0.708 rs17693877 chr6:27707046 G/A cg08851530 chr6:28072375 NA 0.95 4.64 0.38 8.79e-6 Parkinson's disease; TGCT cis rs31872 0.520 rs246053 chr5:140326290 T/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs57590327 0.679 rs13071810 chr3:81618478 T/C cg07356753 chr3:81810745 GBE1 -0.57 -4.72 -0.39 6.37e-6 Extraversion; TGCT cis rs9814567 0.752 rs13075253 chr3:134329600 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.75 6.83 0.52 3.43e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs644799 0.930 rs631099 chr11:95563482 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1005277 0.579 rs1740747 chr10:38520465 G/A cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6582630 0.537 rs35336822 chr12:38346251 T/C cg26384229 chr12:38710491 ALG10B 0.78 6.94 0.53 1.94e-10 Drug-induced liver injury (flucloxacillin); TGCT trans rs751984 0.706 rs11605791 chr11:61263116 C/G cg03305746 chr2:106927199 NA -0.58 -7.01 -0.53 1.32e-10 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs1018836 0.923 rs6986689 chr8:91626709 A/C cg16814680 chr8:91681699 NA -0.85 -9.22 -0.64 9.9e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9372498 0.536 rs1319987 chr6:118782236 A/G cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs7258465 1.000 rs10409483 chr19:18590223 C/G cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs11948739 0.501 rs971699 chr5:130361558 A/G cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Pediatric bone mineral content (hip); TGCT cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg03188948 chr7:1209495 NA 0.65 5.39 0.44 3.36e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1800682 0.528 rs11202918 chr10:90742008 A/G cg03111039 chr10:90751583 FAS;ACTA2 0.62 8.71 0.62 1.58e-14 Chronic lymphocytic leukemia; TGCT cis rs35306767 0.903 rs35567307 chr10:915804 G/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs13326165 0.760 rs56357549 chr3:52374516 T/G cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs8078723 0.714 rs12940405 chr17:38143768 C/T cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.69e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs11105298 0.891 rs10858881 chr12:89891474 T/G cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs9513593 0.892 rs7320298 chr13:99875666 G/T cg21788972 chr13:99853209 UBAC2 0.59 4.7 0.39 6.68e-6 Psoriasis; TGCT cis rs78487399 0.710 rs7607777 chr2:43629931 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -4.87 -0.4 3.39e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs5769707 0.933 rs2157444 chr22:49994292 A/G cg05373962 chr22:49881684 NA -0.3 -6.13 -0.48 1.06e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2404602 0.735 rs11632222 chr15:76712927 C/G cg26408565 chr15:76604113 ETFA 0.38 4.49 0.37 1.58e-5 Blood metabolite levels; TGCT cis rs9650657 0.801 rs7018334 chr8:10612075 G/A cg27411982 chr8:10470053 RP1L1 -0.22 -4.51 -0.38 1.49e-5 Neuroticism; TGCT cis rs3008870 1.000 rs35365746 chr1:67438900 G/A cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs2882877 0.648 rs13018571 chr2:190395126 A/T cg10752008 chr2:190445175 SLC40A1 0.63 4.67 0.39 7.72e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg24675658 chr1:53192096 ZYG11B -0.75 -9.11 -0.63 1.78e-15 Monocyte count; TGCT cis rs4566357 0.615 rs4675140 chr2:227908665 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -5.09 -0.42 1.28e-6 Coronary artery disease; TGCT cis rs9910055 0.530 rs8072954 chr17:42294722 G/A cg13607699 chr17:42295918 UBTF 0.97 11.16 0.71 1.87e-20 Total body bone mineral density; TGCT trans rs7726839 0.574 rs72705014 chr5:619815 C/G cg11887960 chr12:57824829 NA 1.19 9.29 0.64 6.45e-16 Obesity-related traits; TGCT cis rs2033711 0.870 rs11669741 chr19:58960481 C/T cg12042659 chr19:58951599 ZNF132 -0.5 -4.5 -0.37 1.57e-5 Uric acid clearance; TGCT cis rs9611565 0.729 rs202654 chr22:41841034 G/A cg03806693 chr22:41940476 POLR3H 1.03 11.32 0.71 7.58e-21 Vitiligo; TGCT cis rs6964587 0.610 rs10953056 chr7:91466700 C/T cg17063962 chr7:91808500 NA 0.73 6.7 0.52 6.48e-10 Breast cancer; TGCT cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs2066819 0.901 rs773665 chr12:56717466 C/T cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT trans rs4576506 0.536 rs35433184 chr9:31502795 A/G cg11445191 chr5:140227765 PCDHA6;PCDHA2;PCDHA1;PCDHA7;PCDHA5;PCDHA9;PCDHA3;PCDHA4;PCDHA8 0.98 6.69 0.51 6.76e-10 Psychosis and Alzheimer's disease; TGCT cis rs10206020 0.921 rs72776302 chr2:1571383 G/A cg12573674 chr2:1569213 NA -0.49 -5.3 -0.43 5.1e-7 IgG glycosylation; TGCT cis rs1005277 0.522 rs289649 chr10:37975384 T/C cg25427524 chr10:38739819 LOC399744 -0.33 -6.48 -0.5 1.99e-9 Extrinsic epigenetic age acceleration; TGCT cis rs2637266 1.000 rs2637266 chr10:78331318 C/T cg18941641 chr10:78392320 NA -0.39 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg15687855 chr3:44754131 ZNF502 -0.54 -6.78 -0.52 4.27e-10 Depressive symptoms; TGCT cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 4.89 0.4 3.05e-6 Schizophrenia; TGCT cis rs11098499 0.909 rs7681214 chr4:120385320 C/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs10782582 0.532 rs12132503 chr1:76137762 C/G cg03433033 chr1:76189801 ACADM -0.64 -7.35 -0.55 2.29e-11 Daytime sleep phenotypes; TGCT cis rs6684514 1.000 rs12130361 chr1:156260301 C/T cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg18402987 chr7:1209562 NA 0.4 5.17 0.42 9.07e-7 Longevity;Endometriosis; TGCT cis rs6570726 0.935 rs406343 chr6:145874388 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs17401966 1.000 rs17401924 chr1:10384439 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.5 -0.37 1.57e-5 Hepatocellular carcinoma; TGCT cis rs769267 0.895 rs2965183 chr19:19545696 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.25 0.43 6.3e-7 Tonsillectomy; TGCT cis rs1729951 0.575 rs10935214 chr3:136693485 G/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs6582630 0.519 rs8189623 chr12:38351436 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.33e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs2839186 0.732 rs8131458 chr21:47694712 G/A cg12516959 chr21:47718080 NA -0.3 -4.46 -0.37 1.85e-5 Testicular germ cell tumor; TGCT cis rs1218582 0.682 rs12144978 chr1:154850445 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.66 -6.43 -0.5 2.47e-9 Prostate cancer; TGCT cis rs7226408 0.857 rs74682538 chr18:34473572 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6534347 0.573 rs7676741 chr4:123523441 G/A cg10583651 chr4:123538969 IL21 -0.36 -5.27 -0.43 5.97e-7 Type 1 diabetes; TGCT cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg27121462 chr16:89883253 FANCA 0.64 6.14 0.48 1.05e-8 Vitiligo; TGCT cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs5769765 0.913 rs8135071 chr22:50299587 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -10.56 -0.69 5.6e-19 Schizophrenia; TGCT cis rs17345786 1.000 rs11715368 chr3:101336380 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 4.72 0.39 6.29e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs5758659 0.714 rs2284087 chr22:42485671 T/C cg15557168 chr22:42548783 NA 0.18 4.56 0.38 1.23e-5 Cognitive function; TGCT cis rs7833790 0.724 rs6473299 chr8:82676936 A/G cg17211192 chr8:82754475 SNX16 -1.03 -8.39 -0.6 9.37e-14 Diastolic blood pressure; TGCT cis rs1218582 0.774 rs2335409 chr1:154916106 G/A cg06221963 chr1:154839813 KCNN3 -0.8 -14.79 -0.8 3.73e-29 Prostate cancer; TGCT cis rs2301573 1.000 rs2301573 chr3:129305919 A/G cg07730360 chr3:128845626 NA 0.32 5.04 0.41 1.63e-6 Hip circumference; TGCT cis rs1878931 0.535 rs7188903 chr16:3412861 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.73 6.0 0.47 2.01e-8 Body mass index (adult); TGCT cis rs7843479 0.601 rs4872209 chr8:21848832 A/T cg17168535 chr8:21777572 XPO7 0.79 7.79 0.57 2.32e-12 Mean corpuscular volume; TGCT cis rs7412746 0.658 rs1027699 chr1:150811712 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.13 0.42 1.1e-6 Melanoma; TGCT cis rs17221829 0.626 rs10830305 chr11:89366794 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs3733585 0.578 rs6837224 chr4:9955255 G/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2486288 0.656 rs8024620 chr15:45574329 C/T cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.33 -0.43 4.53e-7 Glomerular filtration rate; TGCT cis rs7909074 0.691 rs11239274 chr10:45393219 A/C cg05187965 chr10:45406764 TMEM72 0.23 4.8 0.4 4.46e-6 Mean corpuscular volume; TGCT cis rs2235642 0.821 rs2281236 chr16:1603576 G/A cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -5.06 -0.41 1.46e-6 Coronary artery disease; TGCT cis rs12472274 1.000 rs12472274 chr2:239095422 G/A cg17459225 chr2:239074497 NA 0.33 4.84 0.4 3.79e-6 Phospholipid levels (plasma); TGCT cis rs2836974 0.897 rs2026267 chr21:40711477 C/A cg06238570 chr21:40685208 BRWD1 0.67 5.95 0.47 2.5e-8 Cognitive function; TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg14159672 chr1:205819179 PM20D1 0.6 7.24 0.55 4.04e-11 Menarche (age at onset); TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg24846343 chr22:24311635 DDTL 0.23 5.96 0.47 2.47e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs2303759 0.918 rs8107548 chr19:49870643 T/C cg22307029 chr19:49891270 CCDC155 0.56 5.28 0.43 5.56e-7 Multiple sclerosis; TGCT cis rs6987853 0.931 rs3099936 chr8:42384331 C/T cg20539142 chr8:42623718 CHRNA6 0.21 5.03 0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs13118159 0.872 rs3903127 chr4:1348806 A/C cg13395646 chr4:1353034 KIAA1530 -0.41 -5.04 -0.41 1.58e-6 Longevity; TGCT cis rs6665290 0.904 rs1186 chr1:227177731 A/T cg10327440 chr1:227177885 CDC42BPA -1.01 -20.94 -0.88 1.57e-42 Myeloid white cell count; TGCT cis rs12579753 1.000 rs11115017 chr12:82176914 C/A cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs6840360 1.000 rs2840130 chr4:152600699 T/C cg17479576 chr4:152424074 FAM160A1 -0.52 -5.59 -0.45 1.37e-7 Intelligence (multi-trait analysis); TGCT cis rs36093844 0.898 rs12361645 chr11:85595106 C/G cg25872744 chr11:85566296 CCDC83 -0.51 -4.98 -0.41 2.11e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs473651 0.935 rs540636 chr2:239358341 T/C cg08773314 chr2:239334832 ASB1 0.44 7.18 0.54 5.53e-11 Multiple system atrophy; TGCT cis rs1150668 0.799 rs9301 chr6:28292706 T/C cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.65 -0.39 8.37e-6 Pubertal anthropometrics; TGCT cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg03264133 chr6:25882463 NA 0.48 4.97 0.41 2.19e-6 Blood metabolite levels; TGCT cis rs7772486 0.790 rs9403749 chr6:146162239 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.87 0.4 3.39e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs1932285 chr6:8477719 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2836974 0.831 rs4375956 chr21:40521788 G/A cg11644478 chr21:40555479 PSMG1 1.05 11.19 0.71 1.6e-20 Cognitive function; TGCT cis rs72945132 1.000 rs72945127 chr11:70107650 A/G cg00319359 chr11:70116639 PPFIA1 0.98 7.06 0.54 1.04e-10 Coronary artery disease; TGCT cis rs2180341 0.924 rs877661 chr6:127587915 T/G cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs7267979 1.000 rs13038834 chr20:25441433 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs801193 1.000 rs62466794 chr7:66191579 G/A cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs4808199 0.895 rs2285628 chr19:19467996 T/A cg02546618 chr19:19431379 KIAA0892;SF4 0.65 4.79 0.39 4.73e-6 Nonalcoholic fatty liver disease; TGCT cis rs9911578 0.765 rs66954617 chr17:56999427 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs854572 1.000 rs854572 chr7:94954696 C/G cg04155289 chr7:94953770 PON1 -0.37 -5.97 -0.47 2.28e-8 Paraoxonase activity; TGCT cis rs6547741 1.000 rs6750943 chr2:27777904 T/G cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs6840360 1.000 rs10019048 chr4:152603615 A/G cg17479576 chr4:152424074 FAM160A1 -0.45 -4.72 -0.39 6.36e-6 Intelligence (multi-trait analysis); TGCT cis rs12286929 0.576 rs2275997 chr11:115100186 A/G cg04580443 chr11:115547056 NA -0.24 -4.67 -0.39 7.86e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10927875 0.894 rs34957618 chr1:16320499 G/C cg21385522 chr1:16154831 NA -0.63 -7.07 -0.54 9.8e-11 Dilated cardiomyopathy; TGCT cis rs8038465 0.638 rs12594175 chr15:73973186 C/T cg15420318 chr15:73925796 NPTN 0.72 7.93 0.58 1.09e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs2075371 1.000 rs2544218 chr7:133992315 C/A cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT trans rs797680 0.856 rs11164880 chr1:93658096 A/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.81 -0.52 3.79e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs5769765 0.837 rs8142737 chr22:50291889 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.92 0.47 2.96e-8 Schizophrenia; TGCT cis rs12142240 0.698 rs6703374 chr1:46862332 C/G cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs76878669 0.561 rs4930179 chr11:66157432 C/T cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.87e-9 Educational attainment (years of education); TGCT cis rs6430585 0.697 rs115944351 chr2:136515458 G/A cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs35146811 0.735 rs1727133 chr7:99812870 C/T cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs13191362 0.507 rs2849518 chr6:163134248 T/C cg21926612 chr6:163149169 PACRG;PARK2 -0.58 -5.27 -0.43 5.86e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs116095464 0.558 rs13357299 chr5:242211 T/C cg22857025 chr5:266934 NA -0.34 -6.67 -0.51 7.72e-10 Breast cancer; TGCT cis rs62388641 0.539 rs56016631 chr6:1542575 T/G cg01806741 chr6:1527072 NA -0.31 -4.72 -0.39 6.14e-6 Daytime sleep phenotypes; TGCT cis rs6964587 0.626 rs35849169 chr7:91507313 A/G cg17063962 chr7:91808500 NA 0.72 6.92 0.53 2.16e-10 Breast cancer; TGCT cis rs16867321 0.639 rs12466770 chr2:181441312 C/G cg23363182 chr2:181467187 NA 0.41 6.04 0.48 1.69e-8 Obesity; TGCT cis rs938554 0.513 rs10939650 chr4:9998440 C/T cg11266682 chr4:10021025 SLC2A9 0.51 5.09 0.42 1.28e-6 Blood metabolite levels; TGCT cis rs7267979 0.966 rs6083817 chr20:25343998 G/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4819052 1.000 rs733739 chr21:46666210 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.79 6.02 0.48 1.83e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg25151919 chr3:44754333 ZNF502 -0.47 -5.44 -0.44 2.77e-7 Depressive symptoms; TGCT cis rs1371867 0.846 rs1788205 chr8:101306546 G/C cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT trans rs10504390 0.656 rs76479008 chr8:66486620 G/T cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.26e-10 IgG glycosylation; TGCT cis rs11190604 0.673 rs10883498 chr10:102228709 T/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs8072100 0.667 rs1912485 chr17:45515678 T/G cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2933343 1.000 rs6785869 chr3:128643144 G/A cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs707040 1.000 rs10175148 chr2:155215213 T/C cg18104148 chr2:154337490 NA 0.19 4.76 0.39 5.21e-6 Sudden cardiac arrest; TGCT cis rs1153858 1.000 rs12101539 chr15:45650666 C/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs3862030 0.503 rs10786673 chr10:104280537 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs6988636 0.901 rs16898076 chr8:124187721 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg14893161 chr1:205819251 PM20D1 0.55 7.8 0.57 2.23e-12 Menarche (age at onset); TGCT cis rs1865760 0.516 rs9358903 chr6:26061949 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.45 0.56 1.42e-11 Height; TGCT cis rs7312933 0.703 rs11181380 chr12:42616040 A/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 4.62 0.38 9.51e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2880765 0.835 rs11633604 chr15:86031579 T/G cg13263323 chr15:86062960 AKAP13 -0.22 -4.79 -0.4 4.68e-6 Coronary artery disease; TGCT cis rs4566357 1.000 rs7567789 chr2:227922104 T/C cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs3008870 0.727 rs11208971 chr1:67383901 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.47 0.61 5.86e-14 Lymphocyte percentage of white cells; TGCT cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2486012 0.649 rs39722 chr1:44285663 G/C cg12908607 chr1:44402522 ARTN -0.73 -5.32 -0.43 4.64e-7 Intelligence (multi-trait analysis); TGCT cis rs7100689 0.646 rs1340384 chr10:82088702 T/A cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs17767294 0.708 rs72851138 chr6:28042654 C/T cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs11031096 0.542 rs7924984 chr11:3974588 C/T cg18678763 chr11:4115507 RRM1 -0.43 -5.24 -0.43 6.8e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs11122272 0.735 rs2749699 chr1:231520279 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs7777754 0.512 rs7785224 chr7:50562361 T/C cg18232548 chr7:50535776 DDC -0.4 -6.23 -0.49 6.7e-9 Response to zileuton treatment in asthma (FEV1 change interaction); TGCT cis rs881375 0.867 rs6478487 chr9:123672777 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.97 0.41 2.19e-6 Rheumatoid arthritis; TGCT cis rs4242434 0.672 rs3758041 chr8:22486987 A/G cg03733263 chr8:22462867 KIAA1967 0.98 13.14 0.76 2.97e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2921073 0.510 rs2976945 chr8:8270871 G/T cg15556689 chr8:8085844 FLJ10661 0.71 6.24 0.49 6.43e-9 Parkinson's disease; TGCT cis rs1801251 1.000 rs6717841 chr2:233590255 C/T cg25237894 chr2:233734115 C2orf82 0.32 5.81 0.46 4.94e-8 Coronary artery disease; TGCT cis rs68170813 0.652 rs763386 chr7:107196723 T/C cg02696742 chr7:106810147 HBP1 -0.59 -4.71 -0.39 6.61e-6 Coronary artery disease; TGCT cis rs1215050 0.791 rs548892 chr4:98724701 C/T cg05340658 chr4:99064831 C4orf37 0.44 5.63 0.45 1.15e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2404602 0.647 rs11072620 chr15:77048770 T/A cg23625390 chr15:77176239 SCAPER -0.38 -4.79 -0.39 4.75e-6 Blood metabolite levels; TGCT cis rs986417 0.818 rs10142842 chr14:61085205 C/T cg27398547 chr14:60952738 C14orf39 -1.33 -9.93 -0.67 1.82e-17 Gut microbiota (bacterial taxa); TGCT cis rs40363 0.723 rs2379831 chr16:3538927 T/C cg22508957 chr16:3507546 NAT15 -0.54 -4.89 -0.4 3.04e-6 Tuberculosis; TGCT cis rs10493773 0.748 rs6576784 chr1:86149476 G/A cg17807903 chr1:86174739 ZNHIT6 -0.43 -6.18 -0.49 8.29e-9 Urate levels in overweight individuals; TGCT cis rs8020441 0.588 rs45558232 chr14:51188754 C/T cg04730355 chr14:51134070 SAV1 1.04 7.27 0.55 3.55e-11 Cognitive performance; TGCT cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs6817645 chr4:99016054 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4803455 0.565 rs1025497 chr19:41871254 A/G cg09537434 chr19:41945824 ATP5SL -0.55 -5.44 -0.44 2.76e-7 Migraine;Coronary artery disease; TGCT cis rs244731 1.000 rs244731 chr5:176539679 C/T cg16006841 chr5:176797999 RGS14 0.49 6.28 0.49 5.12e-9 Urate levels in lean individuals; TGCT cis rs2836974 0.568 rs414850 chr21:40543337 A/C cg11644478 chr21:40555479 PSMG1 0.64 5.85 0.47 4.05e-8 Cognitive function; TGCT cis rs2688608 0.617 rs6480709 chr10:75479125 T/C cg15838173 chr10:75533400 FUT11 -0.31 -5.16 -0.42 9.66e-7 Inflammatory bowel disease; TGCT cis rs12497850 0.897 rs6446252 chr3:48911125 C/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs9611565 0.546 rs739134 chr22:42089623 T/C cg06634786 chr22:41940651 POLR3H 0.9 9.03 0.63 2.7e-15 Vitiligo; TGCT cis rs514406 0.683 rs10157120 chr1:53210888 A/G cg24675658 chr1:53192096 ZYG11B -0.81 -9.87 -0.66 2.57e-17 Monocyte count; TGCT cis rs514406 0.727 rs61768342 chr1:53217028 G/A cg25767906 chr1:53392781 SCP2 0.49 5.52 0.44 1.87e-7 Monocyte count; TGCT cis rs12188164 0.965 rs72717435 chr5:448202 G/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.6 -0.38 1.01e-5 Cystic fibrosis severity; TGCT cis rs9549367 0.826 rs35306827 chr13:113869045 G/A cg18105134 chr13:113819100 PROZ -0.36 -5.81 -0.46 4.84e-8 Platelet distribution width; TGCT cis rs6430585 0.702 rs2015532 chr2:136555525 G/T cg07169764 chr2:136633963 MCM6 -1.2 -11.43 -0.72 4.14e-21 Corneal structure; TGCT cis rs7959452 0.640 rs4761154 chr12:69705362 A/G cg20891283 chr12:69753455 YEATS4 -0.66 -6.57 -0.51 1.26e-9 Blood protein levels; TGCT cis rs968451 1.000 rs57078777 chr22:39697458 A/T cg17798944 chr22:39715225 SNORD43;RPL3 0.87 7.73 0.57 3.17e-12 Primary biliary cholangitis; TGCT cis rs752590 0.806 rs4849174 chr2:113973467 T/C cg27425262 chr2:113953981 PSD4;LOC440839 0.39 4.6 0.38 1.01e-5 Mucinous ovarian carcinoma; TGCT cis rs9467773 0.836 rs1977198 chr6:26466225 A/C cg05738196 chr6:26577821 NA 0.66 7.01 0.53 1.35e-10 Intelligence (multi-trait analysis); TGCT cis rs4689592 0.503 rs10516184 chr4:7060959 C/T cg26116260 chr4:7069785 GRPEL1 0.83 6.2 0.49 7.55e-9 Monocyte percentage of white cells; TGCT cis rs9952991 0.566 rs7241016 chr18:12880206 A/G cg23544223 chr18:12777786 NA -0.5 -4.51 -0.38 1.51e-5 Inflammatory skin disease; TGCT cis rs60871478 0.545 rs35400476 chr7:795686 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.44 4.44 0.37 1.96e-5 Cerebrospinal P-tau181p levels; TGCT cis rs3796352 1.000 rs11707780 chr3:53084326 A/G cg07884673 chr3:53033167 SFMBT1 -0.54 -5.95 -0.47 2.57e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4689388 0.609 rs4234729 chr4:6286087 T/C cg25554036 chr4:6271136 WFS1 0.56 6.72 0.52 5.99e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1903068 0.785 rs10020668 chr4:55996903 C/T cg09978860 chr4:56023921 NA 0.55 6.11 0.48 1.17e-8 Endometriosis; TGCT cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg18305652 chr10:134549665 INPP5A 0.31 4.98 0.41 2.09e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11018874 0.597 rs4393275 chr11:89886397 C/T cg14505434 chr11:89522851 NA 0.39 4.5 0.37 1.52e-5 White blood cell types; TGCT cis rs9467773 0.869 rs1796520 chr6:26410800 C/T cg15659132 chr6:26577336 NA -0.53 -5.59 -0.45 1.35e-7 Intelligence (multi-trait analysis); TGCT cis rs732765 0.774 rs67212334 chr14:75317699 A/G cg06637938 chr14:75390232 RPS6KL1 -0.61 -5.19 -0.42 8.27e-7 Non-small cell lung cancer; TGCT cis rs9660180 0.967 rs6603803 chr1:1812688 A/G cg17747265 chr1:1875780 NA -0.42 -8.11 -0.59 4.18e-13 Body mass index; TGCT cis rs4972806 0.814 rs6710370 chr2:177045969 T/C cg13092806 chr2:177043255 NA 0.54 4.88 0.4 3.23e-6 IgG glycosylation; TGCT cis rs11172134 0.508 rs7398426 chr12:57576370 A/C cg19258868 chr12:57585184 LRP1 -0.31 -5.93 -0.47 2.76e-8 Urate levels in overweight individuals; TGCT cis rs2637266 0.905 rs60809084 chr10:78374431 A/C cg18941641 chr10:78392320 NA 0.43 5.37 0.43 3.74e-7 Pulmonary function; TGCT cis rs9814567 1.000 rs6801596 chr3:134252114 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -9.2 -0.64 1.11e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2708977 0.665 rs772173 chr2:97000396 C/T cg14837825 chr2:96917567 TMEM127 -0.28 -4.46 -0.37 1.81e-5 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs854765 0.929 rs854766 chr17:18012775 A/G cg04398451 chr17:18023971 MYO15A -0.3 -4.72 -0.39 6.32e-6 Total body bone mineral density; TGCT cis rs4319547 0.956 rs10744275 chr12:123048618 A/G cg23029597 chr12:123009494 RSRC2 -0.31 -5.1 -0.42 1.24e-6 Body mass index; TGCT cis rs17761864 1.000 rs1555569 chr17:2149425 A/C cg02171503 chr17:1588363 PRPF8 -0.47 -4.48 -0.37 1.64e-5 Esophageal cancer (squamous cell); TGCT cis rs11971779 0.941 rs4732368 chr7:139034207 A/C cg07862535 chr7:139043722 LUC7L2 0.79 5.97 0.47 2.38e-8 Diisocyanate-induced asthma; TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg11494091 chr17:61959527 GH2 -0.61 -14.81 -0.8 3.39e-29 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs13129479 chr4:98987860 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3099143 1.000 rs1913001 chr15:77179408 A/C cg21673338 chr15:77095150 SCAPER 0.54 5.15 0.42 1.01e-6 Recalcitrant atopic dermatitis; TGCT cis rs12477438 0.798 rs12468419 chr2:99579680 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -5.43 -0.44 2.89e-7 Chronic sinus infection; TGCT cis rs12971120 0.947 rs34676212 chr18:72170006 A/G cg26446133 chr18:72167187 CNDP2 -0.4 -7.74 -0.57 3.07e-12 Refractive error; TGCT cis rs9393692 0.676 rs806977 chr6:26189615 A/G cg00631329 chr6:26305371 NA -0.32 -4.65 -0.39 8.31e-6 Educational attainment; TGCT cis rs9611565 1.000 rs5758314 chr22:41762523 T/G cg13695892 chr22:41940480 POLR3H -0.71 -6.96 -0.53 1.71e-10 Vitiligo; TGCT cis rs2303745 0.589 rs7246262 chr19:17392483 C/G cg04248312 chr19:17393744 ANKLE1 -0.33 -5.55 -0.45 1.62e-7 Systemic lupus erythematosus; TGCT cis rs17102423 0.533 rs3783715 chr14:65490018 C/G cg11161011 chr14:65562177 MAX -0.46 -5.33 -0.43 4.45e-7 Obesity-related traits; TGCT cis rs2153535 0.580 rs1119688 chr6:8460850 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg17054783 chr10:134559939 INPP5A 0.25 4.74 0.39 5.75e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1843834 0.539 rs3912999 chr2:225390089 C/T cg22455342 chr2:225449267 CUL3 1.01 10.41 0.68 1.25e-18 IgE levels in asthmatics (D.p. specific); TGCT cis rs9611565 0.512 rs1983576 chr22:42166486 G/A cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs1348850 0.872 rs12991272 chr2:178457339 T/C cg22681709 chr2:178499509 PDE11A -0.45 -5.28 -0.43 5.7e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2692947 0.726 rs13009727 chr2:96769883 C/G cg23100626 chr2:96804247 ASTL -0.39 -4.59 -0.38 1.05e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs698813 0.674 rs6544753 chr2:44501895 A/T cg00619915 chr2:44497795 NA -0.22 -5.06 -0.41 1.48e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs200810 0.694 rs13211103 chr6:98022156 T/A cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.64 -4.45 -0.37 1.91e-5 Body mass index; TGCT cis rs35306767 0.715 rs11253550 chr10:1028288 C/G cg20503657 chr10:835505 NA 0.59 6.67 0.51 7.75e-10 Eosinophil percentage of granulocytes; TGCT cis rs74233809 1.000 rs11191472 chr10:104707016 A/T cg05855489 chr10:104503620 C10orf26 0.75 4.47 0.37 1.72e-5 Birth weight; TGCT cis rs11098499 0.865 rs28845498 chr4:120405186 G/A cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs7312933 0.703 rs11181378 chr12:42600658 T/C cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs425277 1.000 rs262665 chr1:2083173 A/G cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs3749237 1.000 rs11130216 chr3:49736172 C/A cg07636037 chr3:49044803 WDR6 0.65 5.75 0.46 6.7e-8 Resting heart rate; TGCT cis rs10504229 0.871 rs56372514 chr8:58157166 A/G cg20607798 chr8:58055168 NA 0.44 4.45 0.37 1.9e-5 Developmental language disorder (linguistic errors); TGCT cis rs9443645 0.808 rs9361484 chr6:79758218 C/A cg09184832 chr6:79620586 NA -0.47 -5.11 -0.42 1.19e-6 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs16891727 chr6:26488860 C/A cg16898833 chr6:26189333 HIST1H4D 0.94 4.58 0.38 1.12e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs79349575 0.811 rs12601072 chr17:46997998 T/C cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs9394438 0.529 rs10947681 chr6:37547073 C/A cg00985040 chr6:37553208 NA -0.28 -5.67 -0.45 9.41e-8 IgG glycosylation; TGCT cis rs6665290 0.669 rs3768423 chr1:227177293 G/A cg10327440 chr1:227177885 CDC42BPA -0.9 -14.92 -0.8 1.84e-29 Myeloid white cell count; TGCT cis rs7267979 1.000 rs4815408 chr20:25346678 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs877282 0.786 rs10904558 chr10:797509 C/T cg17470449 chr10:769945 NA 0.29 4.64 0.38 8.77e-6 Uric acid levels; TGCT cis rs9733 0.596 rs7529998 chr1:150662531 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs13088281 1.000 rs13088281 chr3:53147576 A/C cg27565382 chr3:53032988 SFMBT1 -0.49 -5.82 -0.46 4.68e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.791 rs1115615 chr4:99006614 G/A cg17366294 chr4:99064904 C4orf37 0.71 7.3 0.55 3.08e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7208859 0.623 rs73269988 chr17:29118145 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs939574 1.000 rs9989854 chr2:220086280 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.03 -6.63 -0.51 9.19e-10 Platelet distribution width; TGCT cis rs2439831 1.000 rs2264239 chr15:43765533 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs12548874 0.618 rs10100651 chr8:95887225 G/C cg13393036 chr8:95962371 TP53INP1 -0.53 -6.28 -0.49 5.19e-9 Hemoglobin concentration; TGCT cis rs860554 0.960 rs832143 chr1:201262755 G/T cg01022117 chr1:201258280 PKP1 0.31 4.85 0.4 3.6e-6 Panic disorder; TGCT cis rs12048904 0.505 rs10493936 chr1:101213335 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.63 -5.4 -0.44 3.27e-7 Multiple sclerosis; TGCT cis rs4731207 0.561 rs12706631 chr7:124586580 G/A cg10503827 chr7:124401702 GPR37 -0.21 -4.53 -0.38 1.37e-5 Cutaneous malignant melanoma; TGCT cis rs11190604 1.000 rs7073586 chr10:102307671 A/G cg16342193 chr10:102329863 NA -0.43 -4.94 -0.41 2.47e-6 Palmitoleic acid (16:1n-7) levels; TGCT trans rs12001652 0.579 rs7029792 chr9:14018144 C/G cg16456503 chr16:67943052 PSKH1 -0.44 -6.75 -0.52 5.03e-10 Carotid plaque burden; TGCT cis rs1865760 0.534 rs2032444 chr6:26046744 T/G cg17042849 chr6:26104293 HIST1H4C -0.82 -7.09 -0.54 8.83e-11 Height; TGCT cis rs546131 0.642 rs523246 chr11:34845011 C/G cg06937548 chr11:34938143 PDHX;APIP 0.54 4.76 0.39 5.38e-6 Lung disease severity in cystic fibrosis; TGCT cis rs2673604 0.513 rs2673606 chr8:133409932 C/T cg05740582 chr8:133573933 HPYR1 -0.31 -4.48 -0.37 1.65e-5 Interleukin-8 levels; TGCT cis rs877282 0.945 rs10904555 chr10:787740 C/A cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs2014572 0.967 rs10426174 chr19:57756055 G/A cg24459738 chr19:57751996 ZNF805 -0.54 -5.4 -0.44 3.21e-7 Hyperactive-impulsive symptoms; TGCT cis rs57994353 0.793 rs35531907 chr9:139327143 C/T cg13741927 chr9:139327495 INPP5E -0.27 -6.26 -0.49 5.81e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9916302 0.904 rs4795359 chr17:37573146 C/T cg15445000 chr17:37608096 MED1 0.34 4.8 0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs77808099 0.590 rs74654914 chr1:15936119 T/C cg05660106 chr1:15850417 CASP9 0.86 4.47 0.37 1.71e-5 Alcoholic chronic pancreatitis; TGCT cis rs7208859 0.673 rs11080135 chr17:29176481 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7655841 0.504 rs337279 chr4:130028426 G/T cg26347359 chr4:129759716 PHF17 -0.45 -6.09 -0.48 1.3e-8 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs10782582 0.569 rs1770892 chr1:76389359 T/C cg03433033 chr1:76189801 ACADM -0.46 -4.56 -0.38 1.19e-5 Daytime sleep phenotypes; TGCT cis rs16957091 0.647 rs4274403 chr15:43345047 T/C cg17935677 chr15:44119062 WDR76 0.56 4.9 0.4 2.93e-6 MGMT methylation in smokers; TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg17178900 chr1:205818956 PM20D1 0.67 8.98 0.63 3.58e-15 Menarche (age at onset); TGCT cis rs4506170 1.000 rs16902102 chr8:128340221 C/A cg07795030 chr8:128802207 NA -0.21 -4.61 -0.38 9.7e-6 Prostate cancer; TGCT cis rs1552244 0.608 rs6764807 chr3:9998803 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.31 -4.82 -0.4 4.12e-6 Alzheimer's disease; TGCT cis rs2075371 1.000 rs2075373 chr7:133984683 A/C cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs4919694 1.000 rs112809537 chr10:104670346 C/T cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs7666738 0.830 rs2865951 chr4:99040191 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.02 0.41 1.79e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs617219 0.737 rs12659709 chr5:78458257 C/G cg23987322 chr5:78407566 BHMT 0.37 4.95 0.41 2.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7681440 0.775 rs6848181 chr4:90807252 T/C cg20003494 chr4:90757398 SNCA -0.62 -5.94 -0.47 2.7e-8 Dementia with Lewy bodies; TGCT cis rs7937682 0.889 rs516263 chr11:111484719 A/C cg09085632 chr11:111637200 PPP2R1B -1.06 -11.52 -0.72 2.48e-21 Primary sclerosing cholangitis; TGCT cis rs9303401 0.659 rs17822837 chr17:56737838 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.83 0.46 4.6e-8 Cognitive test performance; TGCT cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg06481639 chr22:41940642 POLR3H 0.62 5.59 0.45 1.4e-7 Vitiligo; TGCT cis rs651907 0.514 rs12636047 chr3:101434449 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 10.45 0.68 1.02e-18 Colorectal cancer; TGCT cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs1805008 0.568 rs76888998 chr16:89884310 G/T cg08547343 chr16:90038815 CENPBD1;AFG3L1 -0.95 -4.75 -0.39 5.61e-6 Skin colour saturation; TGCT cis rs9325144 0.556 rs34565156 chr12:39028239 G/A cg13010199 chr12:38710504 ALG10B -0.51 -4.63 -0.38 9.17e-6 Morning vs. evening chronotype; TGCT cis rs6938 0.534 rs11636892 chr15:75266049 G/C cg10253484 chr15:75165896 SCAMP2 -0.6 -5.51 -0.44 2.02e-7 Breast cancer; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg20007245 chr22:24372913 LOC391322 0.8 6.8 0.52 3.87e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6430585 0.528 rs3098102 chr2:136654833 C/T cg07169764 chr2:136633963 MCM6 1.16 10.95 0.7 6.06e-20 Corneal structure; TGCT cis rs903263 0.520 rs12756327 chr1:84664640 T/G cg09664975 chr1:84543551 PRKACB 0.68 5.77 0.46 6.07e-8 Breast cancer (male); TGCT cis rs11098499 0.789 rs12498994 chr4:120250818 A/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs7666738 0.830 rs7663438 chr4:99014582 C/T cg17366294 chr4:99064904 C4orf37 0.66 6.55 0.51 1.41e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9436747 0.641 rs3790428 chr1:66042078 G/T cg14976592 chr1:65886160 LEPROT;LEPR 0.55 4.96 0.41 2.32e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs60843830 1.000 rs17713729 chr2:249092 A/C cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.76 0.52 4.84e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7772486 0.738 rs9485039 chr6:146319387 C/T cg05347473 chr6:146136440 FBXO30 0.55 4.92 0.4 2.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs2500424 chr20:25391969 C/T cg14121845 chr20:25566513 NINL -0.5 -5.43 -0.44 2.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1218582 0.772 rs7528532 chr1:154874440 C/T cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs116095464 0.558 rs2288457 chr5:231270 C/T cg22857025 chr5:266934 NA -0.33 -6.6 -0.51 1.1e-9 Breast cancer; TGCT cis rs28374715 0.578 rs7169543 chr15:41620405 T/C cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.93 -0.8 1.76e-29 Ulcerative colitis; TGCT cis rs6933660 0.745 rs6912830 chr6:151743629 A/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.5 -4.63 -0.38 8.93e-6 Menarche (age at onset); TGCT cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs17376456 1.000 rs13185608 chr5:93509688 T/G cg21475434 chr5:93447410 FAM172A 0.62 4.5 0.37 1.54e-5 Diabetic retinopathy; TGCT cis rs11190604 0.806 rs11190510 chr10:102157175 G/A cg16005271 chr10:102321736 NA 0.46 4.72 0.39 6.25e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg25660036 chr4:7070649 GRPEL1 -0.67 -5.81 -0.46 4.85e-8 Monocyte percentage of white cells; TGCT cis rs926938 0.527 rs360672 chr1:115483836 C/T cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs6565180 0.783 rs9888967 chr16:30407979 G/C cg17640201 chr16:30407289 ZNF48 1.02 10.01 0.67 1.19e-17 Tonsillectomy; TGCT cis rs9291683 0.632 rs11734786 chr4:10041499 A/C cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.31e-14 Bone mineral density; TGCT cis rs1577917 0.958 rs13213899 chr6:86473140 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.48 -0.44 2.28e-7 Response to antipsychotic treatment; TGCT cis rs9311474 0.629 rs13081028 chr3:52555316 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.88 0.53 2.59e-10 Electroencephalogram traits; TGCT cis rs9372253 0.645 rs7753212 chr6:110700229 T/C cg00083206 chr6:110721305 DDO -0.37 -5.33 -0.43 4.43e-7 Platelet distribution width; TGCT cis rs909674 0.731 rs6001594 chr22:39837472 C/T cg05872129 chr22:39784769 NA -0.99 -9.43 -0.65 3.04e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs35934224 0.891 rs12158214 chr22:19871691 C/T cg11182965 chr22:19864308 TXNRD2 -0.31 -4.62 -0.38 9.29e-6 Glaucoma (primary open-angle); TGCT cis rs7208859 0.673 rs11656462 chr17:29160700 G/A cg18442181 chr17:29233375 C17orf42 -0.8 -4.78 -0.39 4.92e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.57 -5.01 -0.41 1.79e-6 Prudent dietary pattern; TGCT cis rs864643 0.947 rs704962 chr3:39557120 C/T cg14968361 chr3:39543547 MOBP 0.46 4.49 0.37 1.62e-5 Attention deficit hyperactivity disorder; TGCT cis rs1153858 0.943 rs28605551 chr15:45641720 C/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs9952991 0.941 rs2847278 chr18:12778715 C/T cg23544223 chr18:12777786 NA 0.64 6.12 0.48 1.15e-8 Inflammatory skin disease; TGCT cis rs9291683 0.546 rs10939672 chr4:10052136 A/G cg11266682 chr4:10021025 SLC2A9 0.59 7.25 0.55 3.92e-11 Bone mineral density; TGCT cis rs9549367 0.789 rs9549698 chr13:113877701 A/G cg18105134 chr13:113819100 PROZ -0.36 -5.85 -0.46 4.16e-8 Platelet distribution width; TGCT cis rs9807989 0.507 rs10204757 chr2:102998974 A/C cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg10047753 chr17:41438598 NA 0.95 9.5 0.65 2.09e-16 Menopause (age at onset); TGCT cis rs4727027 0.901 rs66800495 chr7:148763702 T/C cg23583168 chr7:148888333 NA -0.69 -8.72 -0.62 1.5e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7714584 1.000 rs10051804 chr5:150226424 T/C cg22134413 chr5:150180641 NA 0.87 6.89 0.53 2.52e-10 Crohn's disease; TGCT cis rs11696845 0.666 rs6103849 chr20:43365687 C/T cg25301532 chr20:43378953 KCNK15 -0.48 -5.03 -0.41 1.68e-6 Obesity-related traits; TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs9325144 0.560 rs10506127 chr12:39126686 C/G cg26384229 chr12:38710491 ALG10B -0.62 -5.99 -0.47 2.14e-8 Morning vs. evening chronotype; TGCT cis rs11577318 0.579 rs11247936 chr1:26698884 A/G cg15090202 chr1:26687087 NA 0.57 4.49 0.37 1.64e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs6490294 0.904 rs9971871 chr12:112408376 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs7027203 0.964 rs7854075 chr9:96571211 G/A cg14598338 chr9:96623480 NA 0.62 8.9 0.62 5.79e-15 DNA methylation (variation); TGCT cis rs28595532 0.844 rs55845920 chr4:119490085 C/T cg21605333 chr4:119757512 SEC24D 1.33 8.01 0.58 7.07e-13 Cannabis dependence symptom count; TGCT cis rs954108 0.584 rs9314922 chr13:29379229 A/G cg11788234 chr13:29393811 NA 0.5 7.13 0.54 7.46e-11 Obesity-related traits; TGCT cis rs8177253 1.000 rs1358023 chr3:133484393 T/C cg08048268 chr3:133502702 NA -0.65 -9.79 -0.66 3.99e-17 Iron status biomarkers; TGCT cis rs9916302 0.904 rs755500 chr17:37409865 C/T cg07936489 chr17:37558343 FBXL20 -0.56 -4.51 -0.38 1.47e-5 Glomerular filtration rate (creatinine); TGCT cis rs1552244 0.515 rs67626468 chr3:10161518 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.44 -5.51 -0.44 2e-7 Alzheimer's disease; TGCT cis rs681343 0.746 rs633372 chr19:49209226 G/A cg13540341 chr19:49222985 MAMSTR -0.36 -4.9 -0.4 2.92e-6 Lung adenocarcinoma;Primary sclerosing cholangitis;Childhood ear infection; TGCT cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs2842992 0.747 rs733319 chr6:160221475 A/G cg11366901 chr6:160182831 ACAT2 1.03 6.98 0.53 1.59e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs916888 0.821 rs199506 chr17:44859031 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6988636 0.710 rs73339623 chr8:124140288 A/G cg23067535 chr8:124195133 FAM83A -0.38 -4.8 -0.4 4.53e-6 Urinary uromodulin levels; TGCT cis rs7267979 0.903 rs1118963 chr20:25247449 G/A cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8020441 1.000 rs72681677 chr14:51173590 T/G cg04730355 chr14:51134070 SAV1 0.68 5.42 0.44 2.96e-7 Cognitive performance; TGCT cis rs7945705 0.869 rs2742471 chr11:9003953 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.52 -6.01 -0.47 1.93e-8 Hemoglobin concentration; TGCT trans rs1814175 0.817 rs1615305 chr11:49895222 T/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.34 -0.55 2.4e-11 Height; TGCT cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg03264133 chr6:25882463 NA -0.57 -6.08 -0.48 1.37e-8 Blood metabolite levels; TGCT cis rs896854 0.573 rs11996455 chr8:95853708 G/A cg23172400 chr8:95962367 TP53INP1 -0.29 -4.44 -0.37 1.97e-5 Type 2 diabetes; TGCT cis rs12135062 1.000 rs12135062 chr1:3103312 A/C cg21609526 chr1:3105151 PRDM16 0.39 6.62 0.51 9.78e-10 Migraine; TGCT cis rs17384381 0.953 rs11161597 chr1:85784936 G/A cg16011679 chr1:85725395 C1orf52 0.87 6.73 0.52 5.65e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs6089829 0.925 rs2277767 chr20:61666937 G/A cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs9549367 0.789 rs12584008 chr13:113881228 C/T cg18105134 chr13:113819100 PROZ -0.34 -5.45 -0.44 2.63e-7 Platelet distribution width; TGCT cis rs17331151 0.541 rs11709430 chr3:52862055 G/A cg11137980 chr3:52469226 SEMA3G 0.27 4.83 0.4 3.98e-6 Immune reponse to smallpox (secreted IL-2); TGCT trans rs629535 0.767 rs62513418 chr8:70114376 G/T cg21567404 chr3:27674614 NA -0.56 -9.04 -0.63 2.69e-15 Dupuytren's disease; TGCT cis rs644799 0.544 rs499637 chr11:95569183 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.56 5.43 0.44 2.83e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1062177 1.000 rs2915869 chr5:151171509 C/T cg00977110 chr5:151150581 G3BP1 0.4 4.57 0.38 1.16e-5 Preschool internalizing problems; TGCT cis rs35934224 0.783 rs9754418 chr22:19854733 A/G cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT cis rs911555 0.755 rs4906329 chr14:103942669 A/G cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs12216125 0.537 rs12207059 chr6:25922385 C/T cg16482183 chr6:26056742 HIST1H1C 0.94 7.28 0.55 3.36e-11 Iron status biomarkers; TGCT cis rs610932 0.517 rs599862 chr11:59972888 G/A cg18570331 chr11:60101691 MS4A6E 0.52 4.79 0.4 4.6e-6 Alzheimer's disease; TGCT cis rs6121246 0.542 rs6059761 chr20:30110522 G/C cg13852791 chr20:30311386 BCL2L1 0.68 4.5 0.37 1.52e-5 Mean corpuscular hemoglobin; TGCT cis rs5750830 0.649 rs5757663 chr22:39821319 T/C cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs7714584 1.000 rs1863998 chr5:150271753 A/T cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs7246657 0.663 rs9304568 chr19:38054508 C/A cg18154014 chr19:37997991 ZNF793 0.67 4.65 0.39 8.34e-6 Coronary artery calcification; TGCT cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs875971 0.929 rs778692 chr7:65872449 A/G cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg03188948 chr7:1209495 NA 0.65 5.4 0.44 3.26e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1075232 1.000 rs12440544 chr15:32096504 C/T cg01030201 chr15:31746330 NA -0.99 -4.98 -0.41 2.11e-6 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs1538970 1.000 rs2492840 chr1:45849792 C/A cg05343316 chr1:45956843 TESK2 0.66 5.2 0.42 8.13e-7 Platelet count; TGCT trans rs877282 0.891 rs11253355 chr10:768367 C/G cg22713356 chr15:30763199 NA 1.19 9.81 0.66 3.75e-17 Uric acid levels; TGCT cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs11190604 0.767 rs872290 chr10:102198879 G/A cg16005271 chr10:102321736 NA 0.46 4.68 0.39 7.39e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg10047753 chr17:41438598 NA 0.96 9.49 0.65 2.15e-16 Menopause (age at onset); TGCT cis rs854765 0.547 rs2955383 chr17:17941364 A/G cg04398451 chr17:18023971 MYO15A -0.32 -5.15 -0.42 9.85e-7 Total body bone mineral density; TGCT cis rs9467773 0.565 rs4343916 chr6:26522675 A/T cg05738196 chr6:26577821 NA 0.75 9.2 0.64 1.09e-15 Intelligence (multi-trait analysis); TGCT cis rs2836633 0.929 rs58120977 chr21:40037346 C/T cg05519781 chr21:40033154 ERG 0.69 6.81 0.52 3.81e-10 Coronary artery disease; TGCT cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs131777 0.575 rs131760 chr22:51011936 T/C cg25309564 chr22:51001381 C22orf41 0.57 5.45 0.44 2.58e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4819052 0.724 rs1304487 chr21:46657283 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.59 -4.9 -0.4 2.88e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs611744 0.573 rs629996 chr8:109255206 C/T cg21045802 chr8:109455806 TTC35 0.83 8.71 0.62 1.57e-14 Dupuytren's disease; TGCT cis rs7119 0.634 rs2667782 chr15:77862296 A/C cg27398640 chr15:77910606 LINGO1 0.27 4.78 0.39 4.84e-6 Type 2 diabetes; TGCT cis rs9916302 0.808 rs12948906 chr17:37644854 C/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs700651 0.675 rs1371665 chr2:198942568 C/T cg00792783 chr2:198669748 PLCL1 0.54 4.55 0.38 1.28e-5 Intracranial aneurysm; TGCT trans rs208515 0.525 rs10944871 chr6:66690306 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs6460942 1.000 rs77010200 chr7:12290724 G/A cg06484146 chr7:12443880 VWDE -0.54 -4.81 -0.4 4.36e-6 Coronary artery disease; TGCT cis rs6570726 0.791 rs436498 chr6:145876347 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7635838 0.929 rs7638724 chr3:11413387 T/G cg00170343 chr3:11313890 ATG7 0.61 5.78 0.46 5.68e-8 HDL cholesterol; TGCT cis rs6815814 0.904 rs3924113 chr4:38796255 G/T cg02016764 chr4:38805732 TLR1 -0.35 -5.27 -0.43 5.82e-7 Breast cancer; TGCT cis rs507506 0.771 rs929229 chr17:7105399 C/T cg25256661 chr17:7137939 DVL2 0.53 5.1 0.42 1.22e-6 Adiponectin levels; TGCT cis rs7659604 0.540 rs11934307 chr4:122677514 G/A cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs1018836 0.892 rs4140680 chr8:91584157 G/A cg16814680 chr8:91681699 NA -0.73 -7.41 -0.55 1.67e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs12422267 0.536 rs12303484 chr12:132609558 G/A cg09764611 chr12:132620959 NA -0.38 -5.71 -0.46 7.88e-8 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs11585357 0.895 rs72646797 chr1:17613838 C/G cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs2243480 0.708 rs13242216 chr7:65898277 T/C cg07424592 chr7:64974309 NA 1.29 8.01 0.58 7.16e-13 Diabetic kidney disease; TGCT cis rs1018836 0.886 rs10112242 chr8:91642631 G/C cg16814680 chr8:91681699 NA -0.8 -8.6 -0.61 2.89e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs769267 0.930 rs10414830 chr19:19562332 C/T cg08509172 chr19:19383838 TM6SF2 -0.35 -4.63 -0.38 9.18e-6 Tonsillectomy; TGCT cis rs1008375 0.932 rs4698627 chr4:17605959 T/C cg16339924 chr4:17578868 LAP3 0.68 5.4 0.44 3.24e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28437878 1 rs28437878 chr15:78807872 C/T cg06917634 chr15:78832804 PSMA4 -0.69 -5.08 -0.42 1.34e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs782590 0.967 rs17798852 chr2:55805172 A/C cg18811423 chr2:55921094 PNPT1 0.65 6.93 0.53 2.04e-10 Metabolic syndrome; TGCT cis rs2016266 0.684 rs4759021 chr12:53714868 G/A cg16917193 chr12:54089295 NA -0.72 -5.33 -0.43 4.41e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs7524258 0.903 rs6577424 chr1:7292417 C/T cg04342483 chr1:7259290 CAMTA1 0.31 4.49 0.37 1.6e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs6088580 0.634 rs4911419 chr20:32995873 G/A cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs6840360 1.000 rs7439465 chr4:152594814 C/T cg17479576 chr4:152424074 FAM160A1 0.5 5.19 0.42 8.24e-7 Intelligence (multi-trait analysis); TGCT cis rs786425 0.585 rs10773034 chr12:124234253 A/G cg10461218 chr12:124144432 GTF2H3 0.22 4.67 0.39 7.73e-6 Pubertal anthropometrics; TGCT cis rs8111998 0.793 rs10411767 chr19:22757883 A/G cg19914732 chr19:22715077 NA -0.61 -4.66 -0.39 7.87e-6 Corneal structure; TGCT cis rs11122272 0.735 rs2808600 chr1:231534723 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.64 -0.51 8.59e-10 Hemoglobin concentration; TGCT cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg17554472 chr22:41940697 POLR3H -0.43 -4.59 -0.38 1.05e-5 Vitiligo; TGCT trans rs1814175 0.817 rs10839358 chr11:49770972 G/A cg15704280 chr7:45808275 SEPT13 -0.69 -8.05 -0.59 5.61e-13 Height; TGCT cis rs9611565 0.592 rs8779 chr22:42070276 T/C cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Vitiligo; TGCT cis rs9486719 0.741 rs2049927 chr6:96848958 C/G cg18709589 chr6:96969512 KIAA0776 -0.68 -4.67 -0.39 7.79e-6 Migraine;Coronary artery disease; TGCT cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg03161606 chr19:29218774 NA 0.6 5.79 0.46 5.33e-8 Methadone dose in opioid dependence; TGCT cis rs10782582 0.564 rs17647711 chr1:76241710 C/G cg10523679 chr1:76189770 ACADM -0.53 -4.98 -0.41 2.04e-6 Daytime sleep phenotypes; TGCT cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs34526934 0.566 rs62624470 chr2:177040907 C/T cg14324370 chr2:177042789 NA -0.92 -8.73 -0.62 1.45e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs1670533 1.000 rs6857085 chr4:1095920 C/A cg20887711 chr4:1340912 KIAA1530 -0.7 -5.53 -0.45 1.77e-7 Recombination rate (females); TGCT cis rs6750047 0.546 rs2082255 chr2:38273758 C/A cg07380506 chr2:38303506 CYP1B1 0.6 5.41 0.44 3.07e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs7552404 0.961 rs211710 chr1:76109038 G/A cg22875332 chr1:76189707 ACADM -0.79 -9.64 -0.65 9.57e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1008375 1.000 rs28693609 chr4:17645233 C/T cg16339924 chr4:17578868 LAP3 0.61 5.19 0.42 8.41e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11971779 0.680 rs4728465 chr7:139069061 G/A cg07862535 chr7:139043722 LUC7L2 0.71 5.55 0.45 1.63e-7 Diisocyanate-induced asthma; TGCT cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg13695892 chr22:41940480 POLR3H 0.93 9.06 0.63 2.34e-15 Vitiligo; TGCT cis rs2204008 0.837 rs11169157 chr12:37980047 T/C cg13010199 chr12:38710504 ALG10B 0.61 4.89 0.4 3.05e-6 Bladder cancer; TGCT cis rs16837677 0.826 rs3795737 chr1:156697056 A/G cg17331738 chr1:156647236 NES 0.73 5.0 0.41 1.9e-6 Sjögren's syndrome; TGCT cis rs2228479 0.702 rs12600151 chr16:89831558 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7809950 0.953 rs2253271 chr7:107201252 G/C cg23024343 chr7:107201750 COG5 -0.34 -5.26 -0.43 6.08e-7 Coronary artery disease; TGCT cis rs2933343 0.951 rs9871612 chr3:128570402 C/T cg11901034 chr3:128598214 ACAD9 -0.6 -4.74 -0.39 5.76e-6 IgG glycosylation; TGCT cis rs533581 0.866 rs865102 chr16:88969969 A/G cg05579598 chr16:88989069 CBFA2T3 0.34 4.44 0.37 1.94e-5 Social autistic-like traits; TGCT cis rs4746818 0.892 rs2394505 chr10:70871598 A/G cg11621586 chr10:70884670 VPS26A -1.07 -8.75 -0.62 1.32e-14 Left atrial antero-posterior diameter; TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg05064044 chr6:292385 DUSP22 -0.7 -7.29 -0.55 3.15e-11 Menopause (age at onset); TGCT cis rs3780378 0.967 rs62543876 chr9:5085859 G/C cg02405213 chr9:5042618 JAK2 -0.58 -7.4 -0.55 1.78e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs10791323 0.627 rs2723614 chr11:133705871 T/G cg03690763 chr11:133734501 NA -0.35 -5.32 -0.43 4.6e-7 Childhood ear infection; TGCT cis rs7267979 1.000 rs6037095 chr20:25335687 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs3780486 0.505 rs10217267 chr9:33146528 T/C cg20290983 chr6:43655470 MRPS18A 0.77 8.33 0.6 1.28e-13 IgG glycosylation; TGCT cis rs2721195 0.549 rs2620666 chr8:145703413 T/C cg17328964 chr8:145687451 CYHR1 -0.44 -6.66 -0.51 7.97e-10 Age at first birth; TGCT cis rs1156327 0.655 rs4441251 chr16:19325239 C/T cg02978544 chr16:19716338 NA -0.42 -4.46 -0.37 1.82e-5 Periodontal disease-related phenotypes; TGCT cis rs28595532 0.920 rs115154263 chr4:119765307 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.64 0.51 8.6e-10 Cannabis dependence symptom count; TGCT cis rs2302045 1.000 rs55938551 chr2:242033593 G/A cg04553960 chr2:241721320 KIF1A -0.68 -4.61 -0.38 9.94e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs2806561 0.828 rs604030 chr1:23518227 T/C cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs11650494 0.908 rs75092916 chr17:47412578 T/C cg08112188 chr17:47440006 ZNF652 1.04 5.3 0.43 5.13e-7 Prostate cancer; TGCT cis rs2562456 0.876 rs11085467 chr19:21751843 A/G cg01304269 chr19:21688519 ZNF429 0.58 4.74 0.39 5.78e-6 Pain; TGCT cis rs3754214 0.857 rs9126 chr1:150259400 A/C cg09579323 chr1:150459698 TARS2 -0.53 -4.8 -0.4 4.48e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4566357 0.615 rs2272202 chr2:227914625 C/T cg11843606 chr2:227700838 RHBDD1 0.54 5.09 0.42 1.27e-6 Coronary artery disease; TGCT cis rs1799899 0.826 rs1800276 chr3:133461551 C/T cg18342939 chr3:134203408 ANAPC13;CEP63 0.43 4.45 0.37 1.86e-5 Alcohol consumption (transferrin glycosylation); TGCT cis rs8016982 0.674 rs3815953 chr14:81685482 G/A cg01989461 chr14:81687754 GTF2A1 0.81 8.55 0.61 3.82e-14 Schizophrenia; TGCT cis rs9653442 0.835 rs11885529 chr2:100746935 A/G cg22139774 chr2:100720529 AFF3 -0.43 -7.47 -0.56 1.27e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11190604 1.000 rs11190604 chr10:102302457 A/G cg23241863 chr10:102295624 HIF1AN 0.69 5.06 0.41 1.46e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs8177253 1.000 rs8177252 chr3:133480174 C/A cg08048268 chr3:133502702 NA -0.65 -9.83 -0.66 3.21e-17 Iron status biomarkers; TGCT cis rs682748 1.000 rs682748 chr5:17148911 A/G cg23987134 chr5:17158319 LOC285696 -0.23 -5.42 -0.44 2.93e-7 Hippocampal atrophy; TGCT cis rs76419734 1.000 rs111248783 chr4:106770998 C/T cg24545054 chr4:106630052 GSTCD;INTS12 1.09 4.45 0.37 1.9e-5 Post bronchodilator FEV1; TGCT cis rs3796352 1.000 rs7645611 chr3:53125297 G/C cg15956490 chr3:53032818 SFMBT1 0.53 6.22 0.49 6.92e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7809950 1.000 rs7809950 chr7:107237807 T/C cg23024343 chr7:107201750 COG5 0.33 5.23 0.42 7.06e-7 Coronary artery disease; TGCT cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs4689388 0.926 rs4689391 chr4:6280449 G/A cg14416269 chr4:6271139 WFS1 0.38 5.23 0.42 7.12e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2963155 0.518 rs72801090 chr5:142774692 C/T cg17617527 chr5:142782415 NR3C1 0.86 5.51 0.44 2.02e-7 Breast cancer; TGCT cis rs4788570 0.538 rs72797728 chr16:71552789 C/T cg06353428 chr16:71660113 MARVELD3 -1.32 -7.58 -0.56 6.9e-12 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.783 rs58591767 chr17:47026076 G/A cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT trans rs6089829 0.962 rs6062780 chr20:61666648 T/C cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2070488 0.775 rs2186457 chr3:38553965 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.65 6.21 0.49 7.21e-9 Electrocardiographic conduction measures; TGCT cis rs60871478 0.636 rs56393680 chr7:885696 A/G cg00475322 chr7:917719 C7orf20 0.5 4.97 0.41 2.2e-6 Cerebrospinal P-tau181p levels; TGCT cis rs28595532 0.920 rs115226628 chr4:119639818 A/G cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs2836974 0.644 rs1882779 chr21:40690938 T/C cg06238570 chr21:40685208 BRWD1 -0.81 -8.52 -0.61 4.6e-14 Cognitive function; TGCT cis rs7474896 0.559 rs10740949 chr10:37978435 A/G cg25427524 chr10:38739819 LOC399744 -0.31 -4.83 -0.4 3.98e-6 Obesity (extreme); TGCT cis rs16854884 0.837 rs13083068 chr3:143801642 G/T cg06585982 chr3:143692056 C3orf58 0.62 4.82 0.4 4.11e-6 Economic and political preferences (feminism/equality); TGCT cis rs6714710 0.663 rs71429376 chr2:98534412 T/C cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7267979 1.000 rs7343481 chr20:25300113 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13256369 0.802 rs13256404 chr8:8562974 T/C cg17143192 chr8:8559678 CLDN23 0.56 5.31 0.43 4.9e-7 Obesity-related traits; TGCT cis rs6879260 1.000 rs1035411 chr5:179729519 A/G cg23248424 chr5:179741104 GFPT2 -0.37 -7.04 -0.53 1.16e-10 Height; TGCT cis rs10088262 0.629 rs6990565 chr8:124785645 C/A cg20713898 chr8:124780851 FAM91A1 -0.83 -6.7 -0.52 6.41e-10 Pancreatic cancer; TGCT cis rs7552404 0.727 rs2172508 chr1:76320215 A/G cg22875332 chr1:76189707 ACADM 0.58 6.04 0.48 1.7e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6558530 0.666 rs6558518 chr8:1697309 G/T cg09410841 chr8:1729607 CLN8 0.69 6.2 0.49 7.73e-9 Systolic blood pressure; TGCT cis rs2228479 0.541 rs62052173 chr16:89950739 T/C cg06558623 chr16:89946397 TCF25 0.4 4.73 0.39 5.89e-6 Skin colour saturation; TGCT cis rs2956278 0.717 rs2947128 chr12:84689866 C/T cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2721195 0.967 rs1985022 chr8:145684031 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.79 8.23 0.59 2.13e-13 Age at first birth; TGCT cis rs6088580 0.634 rs6059875 chr20:33086090 T/G cg08999081 chr20:33150536 PIGU 0.28 5.56 0.45 1.61e-7 Glomerular filtration rate (creatinine); TGCT cis rs9611565 0.512 rs4820446 chr22:42215684 C/T cg06634786 chr22:41940651 POLR3H -0.84 -7.87 -0.58 1.51e-12 Vitiligo; TGCT cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg18230493 chr5:56204884 C5orf35 0.8 5.92 0.47 2.95e-8 Initial pursuit acceleration; TGCT cis rs6964587 0.967 rs4626516 chr7:91807153 G/C cg17063962 chr7:91808500 NA 0.88 8.95 0.63 4.42e-15 Breast cancer; TGCT cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs12458462 0.851 rs3859317 chr18:77443093 A/C cg11879182 chr18:77439856 CTDP1 0.67 7.67 0.57 4.39e-12 Monocyte count; TGCT cis rs12048904 0.964 rs3188491 chr1:101338482 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.55 5.14 0.42 1.04e-6 Multiple sclerosis; TGCT cis rs78487399 0.710 rs11899863 chr2:43618819 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -4.46 -0.37 1.78e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg25703541 chr22:24373054 LOC391322 -0.91 -11.18 -0.71 1.69e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg05368731 chr17:41323189 NBR1 1.16 13.45 0.77 5.44e-26 Menopause (age at onset); TGCT trans rs1496653 0.602 rs35273607 chr3:23460017 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs425277 1.000 rs262665 chr1:2083173 A/G cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs904251 0.802 rs2646933 chr6:37402070 C/G cg08126542 chr6:37504118 NA -0.42 -4.74 -0.39 5.8e-6 Cognitive performance; TGCT cis rs9309473 0.607 rs6546826 chr2:73599808 A/G cg20560298 chr2:73613845 ALMS1 0.41 4.54 0.38 1.31e-5 Metabolite levels; TGCT cis rs11874712 1.000 rs7244950 chr18:43676523 G/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs12643440 0.538 rs1522081 chr4:17135357 T/C cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs1008375 0.966 rs2098152 chr4:17684392 G/T cg18681998 chr4:17616180 MED28 0.92 10.46 0.68 9.72e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2688608 0.592 rs13013 chr10:75562161 C/A cg04320760 chr10:75533139 FUT11 -0.38 -5.82 -0.46 4.8e-8 Inflammatory bowel disease; TGCT cis rs2797160 0.967 rs2747715 chr6:126007719 A/T cg05901451 chr6:126070800 HEY2 0.75 6.33 0.49 4.14e-9 Endometrial cancer; TGCT cis rs59197085 0.515 rs73238147 chr7:128469917 T/C cg00260937 chr7:128520193 KCP 0.48 5.22 0.42 7.33e-7 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6840360 0.615 rs2406973 chr4:152608339 G/T cg22705602 chr4:152727874 NA 0.34 5.7 0.46 8.09e-8 Intelligence (multi-trait analysis); TGCT cis rs1075232 1.000 rs34959140 chr15:31725223 G/A cg01030201 chr15:31746330 NA -1.01 -5.26 -0.43 6.07e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs8141529 0.504 rs6005915 chr22:29233262 A/G cg02153584 chr22:29168773 CCDC117 0.61 4.46 0.37 1.81e-5 Lymphocyte counts; TGCT cis rs7010267 0.596 rs1485285 chr8:120036138 T/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs7666738 0.830 rs2865978 chr4:99017946 G/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3087591 1.000 rs2057769 chr17:29691368 C/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.08 -0.54 9.25e-11 Hip circumference; TGCT cis rs6840360 0.615 rs55932132 chr4:152463897 G/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs854765 0.547 rs2955383 chr17:17941364 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.46 0.6 6.36e-14 Total body bone mineral density; TGCT cis rs9534288 0.659 rs7996394 chr13:46653503 A/C cg15192986 chr13:46630673 CPB2 -0.53 -6.39 -0.5 3.01e-9 Blood protein levels; TGCT cis rs208520 0.690 rs207077 chr6:66769855 A/C cg07460842 chr6:66804631 NA -0.96 -10.26 -0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs4517514 0.509 rs10765252 chr11:89875664 C/T cg05041596 chr11:89867385 NAALAD2 0.52 4.61 0.38 9.86e-6 Trans fatty acid levels; TGCT cis rs2721195 0.549 rs2620666 chr8:145703413 T/C cg15857475 chr8:145742913 RECQL4;LRRC14 0.86 10.01 0.67 1.17e-17 Age at first birth; TGCT cis rs9733 0.596 rs12063547 chr1:150674053 G/T cg04414720 chr1:150670196 GOLPH3L -0.37 -4.99 -0.41 1.95e-6 Tonsillectomy; TGCT cis rs9487051 0.714 rs9487058 chr6:109631060 A/C cg01475377 chr6:109611718 NA -0.31 -4.73 -0.39 6.12e-6 Reticulocyte fraction of red cells; TGCT cis rs9325144 0.513 rs7977596 chr12:38649067 C/A cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs2456568 0.867 rs7114457 chr11:93657817 C/T cg26875233 chr11:93583750 C11orf90 -0.46 -5.63 -0.45 1.16e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9814567 0.896 rs1357764 chr3:134344928 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.85 7.73 0.57 3.19e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs2727020 0.729 rs2866328 chr11:49282421 A/G cg03929089 chr4:120376271 NA 0.73 8.48 0.61 5.75e-14 Coronary artery disease; TGCT cis rs6582630 0.555 rs10880602 chr12:38505660 T/C cg13010199 chr12:38710504 ALG10B 0.56 4.55 0.38 1.25e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs2299587 0.585 rs2285304 chr8:17797931 T/A cg01800426 chr8:17659068 MTUS1 -0.65 -5.66 -0.45 9.98e-8 Economic and political preferences; TGCT cis rs806215 0.951 rs327521 chr7:127249143 G/A cg25922125 chr7:127225783 GCC1 0.46 4.74 0.39 5.85e-6 Type 2 diabetes; TGCT cis rs3796352 1.000 rs35737577 chr3:53002557 G/C cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9443189 0.570 rs276687 chr6:76429995 G/T cg01950844 chr6:76311363 SENP6 -0.94 -6.03 -0.48 1.78e-8 Prostate cancer; TGCT cis rs854765 0.647 rs854809 chr17:18006539 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.72 7.52 0.56 9.79e-12 Total body bone mineral density; TGCT cis rs1053338 0.529 rs17654237 chr3:63735585 C/A cg22134162 chr3:63841271 THOC7 -0.31 -4.78 -0.39 4.89e-6 Breast cancer; TGCT cis rs3733631 0.947 rs2189220 chr4:104598099 T/A cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT cis rs12210905 1.000 rs9379970 chr6:27255231 T/C cg08851530 chr6:28072375 NA 1.29 5.49 0.44 2.19e-7 Hip circumference adjusted for BMI; TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg26338869 chr17:61819248 STRADA -0.55 -4.95 -0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1372520 0.684 rs2619356 chr4:90750844 C/T cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs10089 1.000 rs4835944 chr5:127490870 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.83 -7.68 -0.57 4.19e-12 Ileal carcinoids; TGCT cis rs7824557 0.527 rs2572447 chr8:11239510 G/A cg21775007 chr8:11205619 TDH -0.68 -6.6 -0.51 1.08e-9 Retinal vascular caliber; TGCT cis rs1113500 0.787 rs12047429 chr1:108633239 C/T cg22161131 chr1:109420278 GPSM2 0.49 4.54 0.38 1.34e-5 Growth-regulated protein alpha levels; TGCT cis rs28595532 0.920 rs115242199 chr4:119728652 A/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs6088590 0.965 rs6087619 chr20:33288511 C/G cg24642439 chr20:33292090 TP53INP2 0.69 6.31 0.49 4.55e-9 Coronary artery disease; TGCT cis rs12887734 0.546 rs66676135 chr14:104271504 G/A cg26031613 chr14:104095156 KLC1 -0.71 -6.13 -0.48 1.06e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg23131131 chr22:24373011 LOC391322 -0.69 -7.06 -0.54 1.07e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7309 0.622 rs4664396 chr2:161901650 C/T cg22496339 chr2:162101262 NA -0.59 -5.59 -0.45 1.36e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Educational attainment; TGCT cis rs9517313 0.770 rs9517301 chr13:99095088 A/G cg07423050 chr13:99094983 FARP1 -0.33 -6.88 -0.53 2.6e-10 Neuroticism; TGCT trans rs7819412 0.775 rs34094119 chr8:10935898 A/G cg06636001 chr8:8085503 FLJ10661 -0.77 -7.07 -0.54 1.01e-10 Triglycerides; TGCT cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs11105298 0.891 rs3741899 chr12:89933931 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.85 -0.4 3.63e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg20637647 chr7:64974828 NA 0.99 5.12 0.42 1.14e-6 Diabetic kidney disease; TGCT cis rs2153535 0.563 rs7739249 chr6:8534590 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.03 0.41 1.71e-6 Motion sickness; TGCT cis rs11190604 1.000 rs10883512 chr10:102308516 A/G cg16342193 chr10:102329863 NA -0.39 -4.95 -0.41 2.36e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg24531977 chr5:56204891 C5orf35 -0.76 -7.56 -0.56 7.68e-12 Initial pursuit acceleration; TGCT cis rs854765 0.505 rs4924832 chr17:17897739 A/G cg09796270 chr17:17721594 SREBF1 0.24 4.67 0.39 7.85e-6 Total body bone mineral density; TGCT cis rs2072499 0.966 rs2842865 chr1:156159532 G/A cg25208724 chr1:156163844 SLC25A44 1.14 16.72 0.83 1.43e-33 Testicular germ cell tumor; TGCT cis rs514406 0.861 rs554760 chr1:53266749 G/A cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT trans rs13064411 0.542 rs9846539 chr3:113228688 A/G cg00307254 chr3:126706825 PLXNA1 0.34 6.78 0.52 4.36e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2933343 0.700 rs789238 chr3:128636715 A/G cg11901034 chr3:128598214 ACAD9 -0.63 -6.04 -0.48 1.68e-8 IgG glycosylation; TGCT cis rs2455799 0.593 rs2047852 chr3:15732539 T/G cg16303742 chr3:15540471 COLQ -0.25 -4.67 -0.39 7.72e-6 Mean platelet volume; TGCT cis rs7666738 0.687 rs6839454 chr4:99073914 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.16 0.54 6.13e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs801193 0.548 rs7805152 chr7:66209253 C/T cg11764359 chr7:65958608 NA 0.54 4.79 0.4 4.68e-6 Aortic root size; TGCT cis rs13256369 0.851 rs12541477 chr8:8563895 G/A cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs2070488 0.965 rs7433277 chr3:38529818 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 8.99 0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs11025559 0.812 rs10766678 chr11:20507180 A/G cg19653624 chr11:20408972 PRMT3 -0.62 -4.86 -0.4 3.47e-6 Pursuit maintenance gain; TGCT cis rs12477438 0.520 rs6542865 chr2:99764521 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs4927850 1.000 rs7630875 chr3:195753766 A/G cg02975922 chr3:195473998 MUC4 -0.25 -5.65 -0.45 1.03e-7 Pancreatic cancer; TGCT cis rs7666738 0.830 rs10000573 chr4:99048785 G/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9399135 0.967 rs7741515 chr6:135374368 C/G cg24558204 chr6:135376177 HBS1L -0.49 -4.97 -0.41 2.15e-6 Red blood cell count; TGCT trans rs10504390 0.585 rs80151640 chr8:66537841 C/T cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.29e-10 IgG glycosylation; TGCT cis rs9527 0.571 rs12765337 chr10:104635344 G/C cg15744005 chr10:104629667 AS3MT -0.47 -5.86 -0.47 3.9e-8 Arsenic metabolism; TGCT cis rs35146811 0.660 rs3779045 chr7:99779259 T/C cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT trans rs916888 0.610 rs199529 chr17:44837217 A/C cg01341218 chr17:43662625 NA 1.08 9.0 0.63 3.23e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10875746 0.669 rs11168499 chr12:48662670 A/G cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs9611565 0.644 rs2413652 chr22:42097238 C/T cg13695892 chr22:41940480 POLR3H 0.84 8.14 0.59 3.45e-13 Vitiligo; TGCT cis rs12477438 0.501 rs13000731 chr2:99795231 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs1218582 0.772 rs2335408 chr1:154915977 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.68 -6.98 -0.53 1.62e-10 Prostate cancer; TGCT cis rs854765 0.583 rs2350977 chr17:17802779 A/G cg09796270 chr17:17721594 SREBF1 0.24 4.71 0.39 6.54e-6 Total body bone mineral density; TGCT cis rs1215050 0.740 rs783941 chr4:99008235 T/C cg17366294 chr4:99064904 C4orf37 -0.54 -5.81 -0.46 4.85e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10540 1.000 rs61876323 chr11:462855 G/A cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs6740322 0.748 rs13402621 chr2:43458611 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -5.65 -0.45 1.03e-7 Coronary artery disease; TGCT cis rs9811920 0.609 rs793467 chr3:99539664 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.91 -0.53 2.21e-10 Axial length; TGCT cis rs2075371 0.611 rs35428392 chr7:134019645 G/A cg11752832 chr7:134001865 SLC35B4 0.69 5.52 0.44 1.86e-7 Mean platelet volume; TGCT cis rs3026101 0.624 rs1065483 chr17:5284770 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.5 4.88 0.4 3.14e-6 Body mass index; TGCT cis rs7104764 1.000 rs10902112 chr11:244106 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs2147959 0.766 rs728964 chr1:228731895 T/A cg22700015 chr1:228743131 NA -0.61 -5.15 -0.42 9.77e-7 Adult asthma; TGCT cis rs11190604 0.767 rs7090150 chr10:102173446 G/T cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT trans rs797680 0.856 rs6680107 chr1:93770880 G/A cg27528825 chr2:159282178 CCDC148 -0.34 -6.71 -0.52 6.19e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs12039431 0.746 rs61776184 chr1:38008523 C/T cg17933807 chr1:38061675 GNL2 -0.8 -7.64 -0.57 5.24e-12 Epithelial ovarian cancer; TGCT cis rs6882076 1.000 rs4704825 chr5:156382308 A/G cg12943317 chr5:156479607 HAVCR1 -0.31 -5.63 -0.45 1.17e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs700590 0.515 rs62380364 chr5:88107337 C/A cg22951263 chr5:87985283 NA -0.54 -5.35 -0.43 4.16e-7 Educational attainment (years of education); TGCT cis rs1799949 0.773 rs2137990 chr17:41317896 T/A cg10047753 chr17:41438598 NA -0.77 -7.28 -0.55 3.43e-11 Menopause (age at onset); TGCT cis rs3812049 0.784 rs6889311 chr5:127431285 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.64 5.87 0.47 3.81e-8 Lymphocyte counts;Red cell distribution width; TGCT trans rs77457752 0.690 rs75036580 chr9:13912781 C/T cg23609682 chr1:3070786 PRDM16 0.48 6.96 0.53 1.78e-10 Breast cancer; TGCT cis rs7216064 0.636 rs4638 chr17:66039350 A/G cg12091567 chr17:66097778 LOC651250 1.08 8.86 0.62 7.21e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9303401 0.538 rs2240259 chr17:56458129 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.56 5.24 0.43 6.54e-7 Cognitive test performance; TGCT cis rs7666738 0.830 rs11932887 chr4:99072965 C/G cg17366294 chr4:99064904 C4orf37 0.76 7.61 0.56 6.06e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1867631 0.958 rs7536188 chr1:67087926 A/T cg13052034 chr1:66999238 SGIP1 -0.58 -4.88 -0.4 3.23e-6 Menopause (age at onset); TGCT cis rs7312933 0.703 rs10880268 chr12:42599122 C/T cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7017914 0.967 rs1471114 chr8:71675547 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs950169 0.920 rs12915390 chr15:84792069 T/C cg17173187 chr15:85201210 NMB 0.5 5.56 0.45 1.61e-7 Schizophrenia; TGCT cis rs1033284 0.666 rs7424161 chr2:141942235 C/T cg20443778 chr2:142887886 LRP1B -0.44 -4.47 -0.37 1.74e-5 Blood pressure (smoking interaction); TGCT cis rs10804591 0.524 rs2811462 chr3:129303436 T/G cg07730360 chr3:128845626 NA 0.21 4.63 0.38 9.19e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7043114 0.525 rs7847929 chr9:95154244 C/T cg14631576 chr9:95140430 CENPP -0.29 -4.79 -0.39 4.76e-6 Height; TGCT cis rs9912789 0.807 rs9896850 chr17:79191726 C/T cg14413466 chr17:79170920 AZI1 -0.25 -4.55 -0.38 1.25e-5 Frontotemporal dementia; TGCT cis rs3087591 0.683 rs2040792 chr17:29628549 G/T cg24425628 chr17:29625626 OMG;NF1 0.42 6.2 0.49 7.68e-9 Hip circumference; TGCT cis rs10089 1.000 rs7703634 chr5:127509223 A/C cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.25e-5 Ileal carcinoids; TGCT cis rs7954584 0.546 rs10840630 chr12:122352445 C/T cg22168489 chr12:122356033 WDR66 0.22 4.79 0.4 4.59e-6 Mean corpuscular volume; TGCT trans rs17685 0.671 rs60303271 chr7:75760008 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6589563 0.609 rs59455853 chr11:116607874 A/T cg01124546 chr11:117515332 DSCAML1 -0.43 -4.54 -0.38 1.31e-5 Eosinophil counts; TGCT cis rs514406 0.861 rs505444 chr1:53251860 C/T cg22166914 chr1:53195759 ZYG11B 0.42 7.35 0.55 2.33e-11 Monocyte count; TGCT cis rs10992471 0.756 rs1121979 chr9:95140218 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.31 -0.49 4.46e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6952808 0.595 rs3800916 chr7:2166072 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -6.17 -0.48 8.78e-9 Bipolar disorder and schizophrenia; TGCT cis rs7246657 0.722 rs28512414 chr19:38056574 T/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs4499344 0.730 rs34270210 chr19:33103945 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.63 0.61 2.53e-14 Mean platelet volume; TGCT cis rs17253792 0.822 rs10083303 chr14:56068521 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs7666738 0.830 rs13122054 chr4:98972974 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 1.000 rs2489034 chr10:102319192 C/T cg23241863 chr10:102295624 HIF1AN 0.69 5.21 0.42 7.75e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs17401966 0.838 rs12120191 chr1:10345772 A/G cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs11711311 1.000 rs9811200 chr3:113531180 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg16049864 chr8:95962084 TP53INP1 -0.75 -10.47 -0.69 9.05e-19 Type 2 diabetes; TGCT cis rs2762353 0.603 rs4145221 chr6:25763192 A/G cg12310025 chr6:25882481 NA 0.49 4.78 0.39 4.77e-6 Blood metabolite levels; TGCT cis rs12701220 0.948 rs10275712 chr7:1082918 G/A cg07217954 chr7:1067459 C7orf50 -0.48 -4.7 -0.39 6.84e-6 Bronchopulmonary dysplasia; TGCT cis rs1467026 0.563 rs58674721 chr3:12811233 G/A cg05775895 chr3:12838266 CAND2 0.72 7.41 0.55 1.73e-11 P wave duration; TGCT cis rs7666738 0.830 rs13149779 chr4:99010145 G/T cg05340658 chr4:99064831 C4orf37 0.5 5.58 0.45 1.42e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs916888 0.821 rs199513 chr17:44856932 A/G cg01341218 chr17:43662625 NA -1.05 -9.43 -0.65 3.03e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11874712 0.623 rs3753069 chr18:43678035 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.49 4.9 0.4 2.91e-6 Migraine - clinic-based; TGCT cis rs9916302 0.851 rs12947620 chr17:37605364 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs17826219 0.706 rs61643715 chr17:29057762 A/G cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs1153858 1.000 rs7181167 chr15:45686236 C/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs2236918 0.664 rs1776158 chr1:242017658 C/T cg04158730 chr1:242011433 EXO1 0.49 4.55 0.38 1.25e-5 Menopause (age at onset); TGCT cis rs2692947 0.537 rs11682182 chr2:96378210 A/G cg23100626 chr2:96804247 ASTL 0.4 4.7 0.39 6.69e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg07424592 chr7:64974309 NA 1.27 7.86 0.58 1.61e-12 Diabetic kidney disease; TGCT cis rs4788570 0.615 rs6499531 chr16:71731485 T/C cg06353428 chr16:71660113 MARVELD3 1.55 12.69 0.75 3.63e-24 Intelligence (multi-trait analysis); TGCT cis rs28374715 0.528 rs28492932 chr15:41624397 G/C cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.93 -0.8 1.76e-29 Ulcerative colitis; TGCT cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs860554 0.546 rs1543806 chr1:201292844 C/T cg01022117 chr1:201258280 PKP1 -0.27 -4.93 -0.4 2.57e-6 Panic disorder; TGCT cis rs35306767 0.761 rs11253557 chr10:1043667 C/T cg26597838 chr10:835615 NA 0.61 6.72 0.52 5.82e-10 Eosinophil percentage of granulocytes; TGCT cis rs8072100 0.840 rs1912482 chr17:45454883 G/A cg08085267 chr17:45401833 C17orf57 -0.46 -5.08 -0.42 1.33e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6964587 1.000 rs3753109 chr7:91630001 G/C cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs72949976 0.606 rs1922797 chr2:214027642 G/A cg08319019 chr2:214017104 IKZF2 0.84 8.21 0.59 2.46e-13 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs2502731 1.000 rs2502731 chr9:130976557 A/G cg13642260 chr9:130955380 CIZ1 -0.47 -5.37 -0.43 3.72e-7 Attention deficit hyperactivity disorder; TGCT cis rs9911578 1.000 rs12952832 chr17:56906254 T/C cg12560992 chr17:57184187 TRIM37 0.75 9.07 0.63 2.26e-15 Intelligence (multi-trait analysis); TGCT cis rs8077889 1.000 rs113919636 chr17:41877740 A/C cg26893861 chr17:41843967 DUSP3 1.1 13.31 0.77 1.17e-25 Triglycerides; TGCT cis rs910316 0.934 rs8016330 chr14:75657507 G/T cg11812906 chr14:75593930 NEK9 -0.72 -6.79 -0.52 4.14e-10 Height; TGCT cis rs9910055 0.747 rs2905981 chr17:42238625 C/T cg13607699 chr17:42295918 UBTF 0.84 7.76 0.57 2.72e-12 Total body bone mineral density; TGCT cis rs5750830 0.649 rs4337572 chr22:39800704 C/G cg11247378 chr22:39784982 NA -0.68 -7.44 -0.56 1.44e-11 Intelligence (multi-trait analysis); TGCT cis rs6429082 0.683 rs2131920 chr1:235579912 T/A cg26050004 chr1:235667680 B3GALNT2 -0.57 -5.03 -0.41 1.7e-6 Adiposity; TGCT cis rs7666738 0.581 rs34205844 chr4:98887494 C/A cg17366294 chr4:99064904 C4orf37 0.67 6.66 0.51 7.79e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs477895 1.000 rs7939107 chr11:64034773 C/T cg04317338 chr11:64019027 PLCB3 0.71 5.75 0.46 6.48e-8 Mean platelet volume; TGCT cis rs145445141 1 rs145445141 chr1:67489169 ATT/A cg08660285 chr1:67390436 MIER1;WDR78 1.1 10.32 0.68 2.06e-18 Neutrophil percentage of white cells; TGCT cis rs9928842 0.770 rs4888364 chr16:75279510 A/G cg09066997 chr16:75300724 BCAR1 0.25 4.63 0.38 9.24e-6 Alcoholic chronic pancreatitis; TGCT cis rs3087591 0.922 rs2905806 chr17:29502507 A/G cg24425628 chr17:29625626 OMG;NF1 0.45 7.23 0.54 4.41e-11 Hip circumference; TGCT cis rs2455799 0.505 rs2028989 chr3:15934874 C/T cg12172478 chr3:16357591 RFTN1 -0.33 -4.81 -0.4 4.31e-6 Mean platelet volume; TGCT cis rs1865760 0.516 rs10807007 chr6:26048931 A/C cg17042849 chr6:26104293 HIST1H4C -0.65 -5.76 -0.46 6.19e-8 Height; TGCT cis rs826838 0.616 rs1601746 chr12:38626195 G/T cg26384229 chr12:38710491 ALG10B -0.54 -4.88 -0.4 3.24e-6 Heart rate; TGCT cis rs4819052 0.918 rs2330013 chr21:46658662 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.78 6.11 0.48 1.2e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8062405 1.000 rs8055138 chr16:28891465 C/T cg09754948 chr16:28834200 ATXN2L 0.6 4.46 0.37 1.79e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7552404 0.731 rs1689275 chr1:76409655 T/C cg03433033 chr1:76189801 ACADM -0.76 -7.81 -0.57 2.07e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13102973 0.710 rs4428340 chr4:135886451 C/T cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs919433 0.679 rs6757632 chr2:198530266 C/T cg00792783 chr2:198669748 PLCL1 0.55 4.93 0.4 2.56e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs10782582 0.569 rs74090722 chr1:76197262 A/G cg10523679 chr1:76189770 ACADM -0.67 -6.67 -0.51 7.54e-10 Daytime sleep phenotypes; TGCT cis rs2115630 0.875 rs8039472 chr15:85361644 A/G cg12863693 chr15:85201151 NMB -0.37 -4.78 -0.39 4.77e-6 P wave terminal force; TGCT cis rs1371867 0.846 rs1660347 chr8:101314980 G/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs4478037 0.749 rs9311003 chr3:33131070 A/G cg19404215 chr3:33155277 CRTAP -0.94 -5.93 -0.47 2.84e-8 Major depressive disorder; TGCT cis rs10875595 0.836 rs758346 chr5:140674734 C/A cg20560182 chr5:140700478 TAF7 -0.64 -4.91 -0.4 2.76e-6 Pulmonary function decline; TGCT cis rs478304 0.903 rs1151502 chr11:65503485 G/C cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.18e-7 Acne (severe); TGCT cis rs12477438 0.798 rs12468419 chr2:99579680 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -4.86 -0.4 3.51e-6 Chronic sinus infection; TGCT cis rs7937682 0.855 rs571462 chr11:111487106 C/G cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs35849525 0.814 rs35491931 chr3:49993462 T/A cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs1048238 0.506 rs698889 chr1:16267040 A/C cg21385522 chr1:16154831 NA -0.57 -6.33 -0.49 4.18e-9 Systolic blood pressure; TGCT cis rs12118280 0.531 rs12402496 chr1:108732781 G/A cg11967332 chr1:108735228 SLC25A24 0.3 4.45 0.37 1.87e-5 Myeloid white cell count; TGCT cis rs6674176 0.660 rs2108202 chr1:44395786 A/G cg13606994 chr1:44402422 ARTN 0.5 5.48 0.44 2.3e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg23758822 chr17:41437982 NA 0.72 6.85 0.52 3.09e-10 Menopause (age at onset); TGCT cis rs9303401 0.704 rs740605 chr17:56604811 C/T cg12560992 chr17:57184187 TRIM37 0.58 6.34 0.49 3.93e-9 Cognitive test performance; TGCT cis rs7223966 1.000 rs11657081 chr17:61792339 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.92 0.4 2.74e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7618915 0.547 rs11130317 chr3:52731483 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.75 -0.39 5.6e-6 Bipolar disorder; TGCT cis rs854765 0.520 rs7219324 chr17:17909775 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.71 -6.93 -0.53 2e-10 Total body bone mineral density; TGCT cis rs9911578 0.967 rs302843 chr17:56727986 C/T cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs9325144 0.560 rs1601745 chr12:38647828 G/A cg26384229 chr12:38710491 ALG10B -0.63 -5.92 -0.47 2.9e-8 Morning vs. evening chronotype; TGCT cis rs7027203 0.828 rs4743934 chr9:96581893 A/G cg13679303 chr9:96623674 NA -0.66 -10.64 -0.69 3.54e-19 DNA methylation (variation); TGCT cis rs2455799 0.517 rs3843387 chr3:15938909 A/C cg12172478 chr3:16357591 RFTN1 0.33 4.82 0.4 4.09e-6 Mean platelet volume; TGCT cis rs1532993 0.518 rs28566098 chr4:98569438 C/T cg05340658 chr4:99064831 C4orf37 -0.38 -4.53 -0.38 1.36e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs2228479 0.850 rs62052711 chr16:89855100 C/A cg06558623 chr16:89946397 TCF25 0.47 4.58 0.38 1.14e-5 Skin colour saturation; TGCT cis rs1403694 0.695 rs13095338 chr3:186435583 T/C cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs739496 0.579 rs9971942 chr12:112256042 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs17001868 0.568 rs742140 chr22:40781586 G/A cg07138101 chr22:40742427 ADSL 0.73 5.47 0.44 2.38e-7 Mammographic density (dense area); TGCT cis rs9400467 0.537 rs354533 chr6:111487104 T/G cg15721981 chr6:111408429 SLC16A10 0.68 4.48 0.37 1.69e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg00343986 chr7:65444356 GUSB 0.26 6.14 0.48 1.02e-8 Aortic root size; TGCT cis rs28595532 0.688 rs116580819 chr4:119767362 T/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs931608 1.000 rs10408585 chr19:22613247 A/G cg23859931 chr19:22123797 NA 0.6 4.66 0.39 7.99e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT trans rs11722228 0.539 rs62287552 chr4:10153197 C/T cg26043149 chr18:55253948 FECH 1.1 12.23 0.74 4.63e-23 Gout;Urate levels;Serum uric acid levels; TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg08736216 chr1:53307985 ZYG11A -0.3 -6.06 -0.48 1.48e-8 Monocyte count; TGCT cis rs2153535 0.580 rs9505467 chr6:8520219 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs17473412 1.000 rs7713551 chr5:122721253 G/T cg15125798 chr5:122621645 NA -0.57 -5.15 -0.42 9.93e-7 Total body bone mineral density; TGCT cis rs1448094 0.511 rs59668915 chr12:86197170 C/T cg02569458 chr12:86230093 RASSF9 0.39 4.97 0.41 2.16e-6 Major depressive disorder; TGCT cis rs2050392 0.517 rs2771242 chr10:30762973 C/T cg13289132 chr10:30722225 MAP3K8 -0.42 -5.02 -0.41 1.79e-6 Inflammatory bowel disease; TGCT cis rs2395909 1 rs2395909 chr7:107292663 G/A cg23024343 chr7:107201750 COG5 0.3 4.75 0.39 5.42e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9308731 0.644 rs7602904 chr2:111880600 C/T cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.18e-9 Chronic lymphocytic leukemia; TGCT cis rs3806843 0.576 rs246049 chr5:140327590 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs6964587 0.933 rs13230837 chr7:91779017 A/G cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.32e-6 Breast cancer; TGCT cis rs7552404 0.731 rs12090849 chr1:76400261 A/G cg22875332 chr1:76189707 ACADM 0.65 6.36 0.5 3.56e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs736408 1.000 rs4687552 chr3:52838402 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.54 4.7 0.39 6.76e-6 Bipolar disorder; TGCT cis rs9952991 0.941 rs1893217 chr18:12809340 A/G cg23598886 chr18:12777645 NA -0.61 -5.47 -0.44 2.35e-7 Inflammatory skin disease; TGCT cis rs8103278 0.507 rs10404220 chr19:46248407 G/A cg14061069 chr19:46274453 DMPK 0.62 10.19 0.68 4.35e-18 Coronary artery disease; TGCT cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg08219700 chr8:58056026 NA 0.3 4.57 0.38 1.14e-5 Developmental language disorder (linguistic errors); TGCT cis rs9322193 0.923 rs2297928 chr6:150039720 G/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2274273 0.774 rs9323278 chr14:55541574 C/G cg01923255 chr14:55878535 KIAA0831 0.57 4.89 0.4 3.03e-6 Protein biomarker; TGCT trans rs7618501 0.699 rs1317154 chr3:49910084 T/C cg21659725 chr3:3221576 CRBN 0.78 9.37 0.64 4.19e-16 Intelligence (multi-trait analysis); TGCT cis rs11105298 0.891 rs1054807 chr12:89913419 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.75e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4906332 0.933 rs35999760 chr14:103924481 A/C cg26031613 chr14:104095156 KLC1 -0.53 -4.71 -0.39 6.62e-6 Coronary artery disease; TGCT cis rs2562456 0.793 rs2562420 chr19:21631305 T/A cg01304269 chr19:21688519 ZNF429 -0.61 -4.81 -0.4 4.22e-6 Pain; TGCT cis rs2236918 1.000 rs735943 chr1:242030151 C/T cg04158730 chr1:242011433 EXO1 -0.53 -4.62 -0.38 9.28e-6 Menopause (age at onset); TGCT cis rs1348850 0.874 rs4893822 chr2:178285727 G/T cg22681709 chr2:178499509 PDE11A -0.36 -4.59 -0.38 1.06e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg27454412 chr7:1067447 C7orf50 0.57 4.43 0.37 2.01e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6582630 0.585 rs12422588 chr12:38478675 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2463822 0.920 rs7924998 chr11:62073980 C/G cg06239285 chr11:62104954 ASRGL1 -0.89 -5.52 -0.44 1.89e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7552404 0.961 rs1767458 chr1:76219155 A/G cg03433033 chr1:76189801 ACADM 0.75 8.76 0.62 1.19e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.645 rs847627 chr11:49927177 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs9486719 1.000 rs34209750 chr6:96882215 G/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs5750830 0.649 rs5750813 chr22:39795228 G/C cg01416388 chr22:39784598 NA -0.72 -7.11 -0.54 8.03e-11 Intelligence (multi-trait analysis); TGCT cis rs3181245 0.641 rs3756821 chr6:24646821 C/T cg16906346 chr6:24646782 KIAA0319 -0.51 -5.78 -0.46 5.63e-8 Colorectal or endometrial cancer; TGCT cis rs7666738 0.830 rs7686456 chr4:99019695 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7178572 0.889 rs7177055 chr15:77832762 A/G cg22256960 chr15:77711686 NA 0.92 10.82 0.7 1.27e-19 Type 2 diabetes; TGCT cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs832540 0.629 rs6888317 chr5:56093307 A/G cg24531977 chr5:56204891 C5orf35 0.51 5.0 0.41 1.89e-6 Coronary artery disease; TGCT trans rs114540395 0.777 rs9420863 chr10:103362726 C/T cg10198749 chr1:39920707 MACF1 0.55 7.03 0.53 1.2e-10 Schizophrenia; TGCT cis rs1171582 0.564 rs6479648 chr10:61510559 G/A cg23572703 chr10:62241191 NA -0.29 -4.8 -0.4 4.55e-6 Alopecia areata; TGCT cis rs9427116 0.502 rs6699825 chr1:154582970 A/G cg17218026 chr1:154582156 ADAR 0.31 7.7 0.57 3.72e-12 Blood protein levels; TGCT cis rs7666738 0.791 rs1115615 chr4:99006614 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.98 0.41 2.1e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs904251 0.772 rs1812186 chr6:37465916 T/C cg08126542 chr6:37504118 NA -0.39 -4.55 -0.38 1.28e-5 Cognitive performance; TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs11585357 1.000 rs11203346 chr1:17600822 A/G cg08277548 chr1:17600880 PADI3 -0.97 -9.78 -0.66 4.23e-17 Hair shape; TGCT cis rs4665809 0.680 rs3955310 chr2:26290828 T/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs2354432 0.556 rs4295925 chr1:146857335 T/C cg25205988 chr1:146714368 CHD1L 1.32 5.88 0.47 3.62e-8 Mitochondrial DNA levels; TGCT cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg24549020 chr5:56110836 MAP3K1 0.71 6.15 0.48 9.56e-9 Initial pursuit acceleration; TGCT cis rs7192750 0.586 rs4788584 chr16:71993386 A/T cg06353428 chr16:71660113 MARVELD3 0.76 6.52 0.51 1.6e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2072499 0.966 rs2244144 chr1:156184598 G/A cg06970220 chr1:156163860 SLC25A44 0.74 5.91 0.47 3.05e-8 Testicular germ cell tumor; TGCT cis rs7666738 0.830 rs10049985 chr4:99023517 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12220238 1.000 rs10824090 chr10:75923446 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs6089584 0.888 rs6061982 chr20:60620673 C/T cg06108461 chr20:60628389 TAF4 -0.69 -10.64 -0.69 3.59e-19 Body mass index; TGCT cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg15659132 chr6:26577336 NA 0.84 10.28 0.68 2.58e-18 Intelligence (multi-trait analysis); TGCT cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs7267979 0.789 rs1983974 chr20:25530619 A/C cg16686733 chr20:25566563 NINL -0.51 -4.91 -0.4 2.82e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17221829 0.733 rs11018686 chr11:89365241 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs7511006 0.859 rs7292228 chr22:50649560 C/G cg08875078 chr22:50639485 SELO 0.56 5.41 0.44 3.12e-7 Obesity-related traits; TGCT cis rs7772486 0.701 rs7772717 chr6:145954854 T/C cg13319975 chr6:146136371 FBXO30 -0.56 -5.06 -0.41 1.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1215050 0.791 rs700738 chr4:98907909 C/A cg05340658 chr4:99064831 C4orf37 -0.46 -5.82 -0.46 4.74e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg03396347 chr1:1875803 NA -0.3 -5.08 -0.42 1.32e-6 Body mass index; TGCT cis rs9915657 0.966 rs8071717 chr17:70128705 C/T cg06234051 chr17:70120541 SOX9 -0.28 -5.54 -0.45 1.72e-7 Thyroid hormone levels; TGCT cis rs10507380 0.843 rs74615458 chr13:27859246 C/T cg25543773 chr13:27185723 WASF3 0.29 4.45 0.37 1.86e-5 Electrocardiographic traits; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/CA cg23034840 chr1:205782522 SLC41A1 -0.76 -4.92 -0.4 2.7e-6 Menarche (age at onset); TGCT cis rs9611565 0.559 rs5758397 chr22:42019251 C/T cg17554472 chr22:41940697 POLR3H 0.5 5.26 0.43 6.02e-7 Vitiligo; TGCT cis rs875971 1.000 rs778710 chr7:65854834 T/C cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs7223966 0.691 rs9893518 chr17:62006997 A/G cg18032289 chr17:61959525 GH2 -0.31 -4.69 -0.39 7.12e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7172971 0.808 rs55905344 chr15:42340178 C/T cg05886115 chr15:42349113 NA 0.32 4.92 0.4 2.71e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs597539 0.652 rs478647 chr11:68700424 C/T cg06112835 chr11:68658793 MRPL21 0.45 7.64 0.57 5.19e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs877282 0.945 rs877280 chr10:771599 C/T cg22713356 chr15:30763199 NA 1.2 10.36 0.68 1.66e-18 Uric acid levels; TGCT cis rs568617 0.953 rs583887 chr11:65644027 T/C cg04055107 chr11:65626734 MUS81;CFL1 -0.57 -5.22 -0.42 7.39e-7 Crohn's disease; TGCT cis rs4819052 0.655 rs2330102 chr21:46690968 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.64 6.19 0.49 8.26e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7267979 0.932 rs449703 chr20:25458559 C/T cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg21548813 chr6:291882 DUSP22 -0.72 -7.59 -0.56 6.53e-12 Menopause (age at onset); TGCT cis rs35306767 0.953 rs34405399 chr10:981015 G/A cg26597838 chr10:835615 NA 0.56 7.7 0.57 3.66e-12 Eosinophil percentage of granulocytes; TGCT cis rs12765878 1.000 rs2273698 chr10:105649158 G/A cg11005552 chr10:105648138 OBFC1 0.44 7.69 0.57 4.01e-12 Coronary artery disease; TGCT cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg05665937 chr4:1216051 CTBP1 0.24 4.47 0.37 1.72e-5 Obesity-related traits; TGCT cis rs7412746 0.621 rs72704656 chr1:150828307 A/G cg04414720 chr1:150670196 GOLPH3L 0.39 4.75 0.39 5.55e-6 Melanoma; TGCT cis rs2295359 0.892 rs4655687 chr1:67649946 C/T cg08029281 chr1:67600428 NA 0.4 4.68 0.39 7.42e-6 Psoriasis; TGCT cis rs7255045 0.752 rs2418568 chr19:12987881 A/G cg23899408 chr19:12877188 HOOK2 -0.61 -5.01 -0.41 1.79e-6 Mean corpuscular volume; TGCT cis rs9443645 0.901 rs9443622 chr6:79582790 C/T cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs9473924 0.542 rs2857482 chr6:50790642 C/T cg14470998 chr6:50812995 TFAP2B 1.34 7.28 0.55 3.38e-11 Body mass index; TGCT cis rs5769765 0.542 rs1535189 chr22:50249131 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.97 6.35 0.5 3.69e-9 Schizophrenia; TGCT cis rs793108 0.869 rs1624116 chr10:31435153 G/A cg24861272 chr10:31607153 ZEB1;LOC220930 0.29 4.46 0.37 1.84e-5 Multiple sclerosis;Rheumatoid arthritis; TGCT cis rs4144743 1.000 rs34182248 chr17:45321359 T/C cg18085866 chr17:45331354 ITGB3 -0.72 -4.85 -0.4 3.61e-6 Body mass index; TGCT cis rs367615 0.659 rs13435970 chr5:108884660 C/T cg17395555 chr5:108820864 NA 0.3 4.92 0.4 2.73e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg07806771 chr7:64541737 NA 0.45 4.59 0.38 1.06e-5 Calcium levels; TGCT cis rs6893300 0.524 rs6601073 chr5:179177271 A/G cg14593053 chr5:179126677 CANX -0.49 -5.63 -0.45 1.16e-7 Resting heart rate; TGCT cis rs7178572 0.568 rs28524916 chr15:77599002 T/A cg15453836 chr15:77711506 NA 0.42 4.79 0.4 4.68e-6 Type 2 diabetes; TGCT cis rs9649213 0.614 rs3801258 chr7:97988428 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.73 -0.62 1.45e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs2404602 0.692 rs34272342 chr15:77012276 A/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs4761974 1.000 rs74583309 chr12:51880093 A/G cg09925572 chr12:51518419 TFCP2 0.5 4.53 0.38 1.35e-5 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs2153535 0.601 rs9406160 chr6:8464907 A/C cg07606381 chr6:8435919 SLC35B3 0.55 5.16 0.42 9.35e-7 Motion sickness; TGCT cis rs514406 0.861 rs4926576 chr1:53226775 C/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.29e-11 Monocyte count; TGCT cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg22963979 chr7:1858916 MAD1L1 -0.45 -7.41 -0.55 1.74e-11 Bipolar disorder and schizophrenia; TGCT cis rs1891275 0.515 rs1986941 chr10:93444343 C/T cg07889827 chr10:93443413 NA -0.33 -6.99 -0.53 1.53e-10 Intelligence (multi-trait analysis); TGCT cis rs10489202 0.612 rs3820401 chr1:168074753 T/C cg24449463 chr1:168025552 DCAF6 -0.53 -5.49 -0.44 2.16e-7 Schizophrenia; TGCT trans rs7819412 0.838 rs3021494 chr8:10983534 A/G cg15556689 chr8:8085844 FLJ10661 -0.8 -7.94 -0.58 1.03e-12 Triglycerides; TGCT cis rs7666738 0.791 rs6532725 chr4:99061479 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.720 rs7752286 chr6:146072662 C/T cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6840360 0.617 rs2724563 chr4:152349959 G/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.764 rs2247211 chr6:146216379 G/A cg23711669 chr6:146136114 FBXO30 0.87 9.97 0.67 1.48e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs151997 0.925 rs27847 chr5:50176197 G/T cg06027927 chr5:50259733 NA 0.46 4.63 0.38 9.01e-6 Callous-unemotional behaviour; TGCT cis rs6450176 0.625 rs16881958 chr5:53288201 C/G ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.53 -0.44 1.8e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.98 10.79 0.7 1.55e-19 Intelligence (multi-trait analysis); TGCT cis rs4642101 0.535 rs55692304 chr3:12840057 C/T cg05775895 chr3:12838266 CAND2 0.84 9.56 0.65 1.45e-16 QRS complex (12-leadsum); TGCT cis rs344364 0.511 rs1657134 chr16:1953127 A/G cg26617929 chr16:1858877 NA -0.26 -4.66 -0.39 8.04e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs12477438 1.000 rs1922624 chr2:99909958 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.8 -6.4 -0.5 2.92e-9 Chronic sinus infection; TGCT trans rs57221529 0.713 rs56328416 chr5:591138 G/A cg11887960 chr12:57824829 NA 1.17 9.69 0.66 6.98e-17 Lung disease severity in cystic fibrosis; TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg06873352 chr17:61820015 STRADA 0.58 6.36 0.5 3.51e-9 Prudent dietary pattern; TGCT cis rs7119038 0.818 rs3889239 chr11:118619960 C/T cg19308663 chr11:118741387 NA 0.29 5.39 0.44 3.41e-7 Sjögren's syndrome; TGCT cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg00343986 chr7:65444356 GUSB -0.25 -5.8 -0.46 5.09e-8 Aortic root size; TGCT cis rs7246657 0.722 rs8100646 chr19:38107943 T/C cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs10504229 1.000 rs68114352 chr8:58196081 C/T cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs9517313 0.523 rs4772104 chr13:99235677 G/A cg07423050 chr13:99094983 FARP1 -0.23 -4.53 -0.38 1.39e-5 Neuroticism; TGCT cis rs4700695 0.511 rs29443 chr5:65504927 G/A cg21114390 chr5:65439923 SFRS12 -0.79 -7.28 -0.55 3.36e-11 Facial morphology (factor 19); TGCT cis rs7208859 0.673 rs78799101 chr17:29215160 A/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2235642 1.000 rs2076438 chr16:1584618 T/C cg07341220 chr16:1583899 IFT140;TMEM204 -0.29 -4.64 -0.38 8.66e-6 Coronary artery disease; TGCT cis rs6121246 0.954 rs6060989 chr20:30429763 C/T cg13852791 chr20:30311386 BCL2L1 0.76 5.67 0.45 9.7e-8 Mean corpuscular hemoglobin; TGCT cis rs2070488 0.689 rs6809352 chr3:38544349 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.55 -0.51 1.4e-9 Electrocardiographic conduction measures; TGCT cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg02725872 chr8:58115012 NA -0.4 -4.83 -0.4 3.92e-6 Developmental language disorder (linguistic errors); TGCT cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg18765753 chr7:1198926 ZFAND2A -0.5 -5.96 -0.47 2.45e-8 Longevity;Endometriosis; TGCT cis rs1048238 0.846 rs945417 chr1:16344625 C/G cg22431228 chr1:16359049 CLCNKA -0.29 -6.2 -0.49 7.76e-9 Systolic blood pressure; TGCT cis rs7954584 0.583 rs6486782 chr12:122359172 T/C cg10207240 chr12:122356781 WDR66 0.34 4.68 0.39 7.53e-6 Mean corpuscular volume; TGCT cis rs9926296 0.581 rs2108838 chr16:89904426 A/G cg26513180 chr16:89883248 FANCA 0.76 7.62 0.56 5.81e-12 Vitiligo; TGCT cis rs79976124 0.797 rs78317899 chr6:66652896 C/A cg07460842 chr6:66804631 NA 0.58 5.29 0.43 5.33e-7 Type 2 diabetes; TGCT cis rs6831352 0.879 rs56295995 chr4:100060899 C/T cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs9914544 1.000 rs9914544 chr17:18787828 A/C cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.41 1.36e-6 Educational attainment (years of education); TGCT cis rs10875595 0.836 rs6889723 chr5:140676524 C/T cg24830062 chr5:140700576 TAF7 -0.75 -6.26 -0.49 5.78e-9 Pulmonary function decline; TGCT cis rs7017914 0.934 rs7009297 chr8:71672366 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg00786635 chr1:25594202 NA 0.59 6.21 0.49 7.4e-9 Erythrocyte sedimentation rate; TGCT cis rs1568889 0.548 rs34906813 chr11:28508819 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.66 4.62 0.38 9.62e-6 Bipolar disorder; TGCT trans rs7613875 0.600 rs2856238 chr3:50158191 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.85 8.89 0.62 6.01e-15 Body mass index; TGCT cis rs6754311 0.861 rs12475139 chr2:136786651 A/T cg07169764 chr2:136633963 MCM6 0.51 4.54 0.38 1.3e-5 Mosquito bite size; TGCT cis rs853679 0.598 rs9380054 chr6:28067537 G/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs877282 0.947 rs7904978 chr10:768078 C/T cg17470449 chr10:769945 NA 0.34 5.13 0.42 1.1e-6 Uric acid levels; TGCT cis rs11190604 1.000 rs2489036 chr10:102319581 A/G cg16342193 chr10:102329863 NA -0.39 -5.0 -0.41 1.92e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs9393777 0.513 rs6904071 chr6:27047256 G/A cg16898833 chr6:26189333 HIST1H4D 0.8 4.85 0.4 3.57e-6 Intelligence (multi-trait analysis); TGCT cis rs9914988 0.832 rs4795462 chr17:27130991 C/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs16866061 0.816 rs115900205 chr2:225467840 G/C cg12698349 chr2:225449008 CUL3 1.0 9.08 0.63 2.11e-15 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs2404602 0.536 rs7163946 chr15:76766049 C/G cg26408565 chr15:76604113 ETFA -0.37 -4.99 -0.41 2.03e-6 Blood metabolite levels; TGCT cis rs7666738 0.830 rs2865949 chr4:99039967 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2742417 0.967 rs1969625 chr3:45734975 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6723226 0.806 rs2249109 chr2:32750879 G/A cg02381751 chr2:32503542 YIPF4 0.55 5.05 0.41 1.56e-6 Intelligence (multi-trait analysis); TGCT cis rs9816226 0.590 rs869401 chr3:185826546 G/A cg00760338 chr3:185826511 ETV5 0.69 6.17 0.48 8.7e-9 Obesity;Body mass index; TGCT cis rs77741769 0.507 rs11065264 chr12:121218380 T/G cg02419362 chr12:121203948 SPPL3 0.19 4.47 0.37 1.74e-5 Mean corpuscular volume; TGCT cis rs67311347 1.000 rs1466236 chr3:40462162 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs6714788 0.503 rs2309748 chr2:100681449 A/T cg22139774 chr2:100720529 AFF3 -0.4 -6.15 -0.48 9.58e-9 Intelligence (multi-trait analysis); TGCT cis rs875971 0.638 rs10249404 chr7:66046724 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs4242434 0.927 rs7843828 chr8:22463623 C/T cg03733263 chr8:22462867 KIAA1967 1.14 20.27 0.88 3.6e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs651907 0.535 rs35799195 chr3:101521927 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs981844 0.775 rs62323976 chr4:154739032 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.8 0.62 9.72e-15 Response to statins (LDL cholesterol change); TGCT cis rs950169 0.519 rs7237 chr15:85186577 C/T cg11189052 chr15:85197271 WDR73 0.68 5.82 0.46 4.72e-8 Schizophrenia; TGCT cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg16414030 chr3:133502952 NA -0.65 -10.6 -0.69 4.35e-19 Iron status biomarkers; TGCT cis rs12142240 0.698 rs17361819 chr1:46828109 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs11677416 1.000 rs2856836 chr2:113532083 A/G cg27083787 chr2:113543245 IL1A 0.18 4.5 0.37 1.53e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs13256369 1.000 rs873063 chr8:8572447 A/G cg17143192 chr8:8559678 CLDN23 0.62 5.83 0.46 4.57e-8 Obesity-related traits; TGCT cis rs2730245 0.583 rs2788473 chr7:158649280 T/C cg11984989 chr7:158649758 WDR60 1.04 9.33 0.64 5.3e-16 Height; TGCT cis rs6088590 1.000 rs11696546 chr20:33452999 C/G cg06115741 chr20:33292138 TP53INP2 0.64 5.1 0.42 1.25e-6 Coronary artery disease; TGCT cis rs12510870 0.599 rs34773614 chr4:74452245 A/G cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs9921222 1.000 rs9921222 chr16:375782 A/G cg08923669 chr16:420230 MRPL28 0.48 5.03 0.41 1.71e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg07424592 chr7:64974309 NA -1.17 -8.11 -0.59 4.19e-13 Diabetic kidney disease; TGCT cis rs13256369 1.000 rs10088439 chr8:8576699 T/G cg18904891 chr8:8559673 CLDN23 0.63 5.82 0.46 4.83e-8 Obesity-related traits; TGCT cis rs72781680 0.660 rs72780104 chr2:23983715 A/G cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs17253792 0.822 rs17253723 chr14:56154015 A/G cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs7666738 0.791 rs7658177 chr4:99035192 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7809950 0.773 rs62483722 chr7:107186349 C/T cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs2688608 0.592 rs7923045 chr10:75487498 A/T cg23231163 chr10:75533350 FUT11 -0.27 -4.67 -0.39 7.62e-6 Inflammatory bowel disease; TGCT cis rs889312 0.500 rs252905 chr5:56118875 C/T cg24531977 chr5:56204891 C5orf35 -0.53 -5.43 -0.44 2.89e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs1150668 0.796 rs1005125 chr6:28367355 G/A cg19488431 chr6:28601329 NA 0.2 4.54 0.38 1.33e-5 Pubertal anthropometrics; TGCT cis rs4660261 0.526 rs3011228 chr1:44325995 A/G cg12908607 chr1:44402522 ARTN -0.64 -7.74 -0.57 3e-12 Intelligence (multi-trait analysis); TGCT cis rs9733 0.519 rs1336900 chr1:150679033 C/T cg04414720 chr1:150670196 GOLPH3L 0.34 4.56 0.38 1.23e-5 Tonsillectomy; TGCT cis rs2204008 0.694 rs1672436 chr12:38132547 G/T cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs7523050 0.730 rs67312582 chr1:109423976 A/G cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs7213347 1.000 rs7213347 chr17:2153257 G/C cg20777128 chr17:1945076 DPH1;OVCA2 -0.49 -4.48 -0.37 1.67e-5 Total body bone mineral density; TGCT cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg03517284 chr6:25882590 NA 0.52 5.29 0.43 5.39e-7 Blood metabolite levels; TGCT cis rs3020736 0.500 rs2413672 chr22:42513261 C/T cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs113084984 0.718 rs1865574 chr2:11681438 A/G cg25804072 chr2:10829725 NOL10 0.56 4.69 0.39 7.01e-6 Breast cancer; TGCT cis rs78487399 0.808 rs7587268 chr2:43673892 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.04 -0.41 1.62e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7829975 0.511 rs2980426 chr8:8145609 T/C cg06636001 chr8:8085503 FLJ10661 0.78 6.9 0.53 2.37e-10 Mood instability; TGCT cis rs9372498 0.536 rs17424234 chr6:118808521 A/G cg21191810 chr6:118973309 C6orf204 -0.37 -4.76 -0.39 5.36e-6 Diastolic blood pressure; TGCT cis rs7614311 0.639 rs111234932 chr3:63842449 C/T cg22134162 chr3:63841271 THOC7 -0.42 -4.68 -0.39 7.4e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs11650494 0.908 rs79768864 chr17:47446968 C/A cg08112188 chr17:47440006 ZNF652 1.04 5.31 0.43 4.85e-7 Prostate cancer; TGCT cis rs9811920 0.928 rs2130369 chr3:99873317 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.41 -4.58 -0.38 1.14e-5 Axial length; TGCT cis rs910316 1.000 rs876402 chr14:75601862 C/T cg23033748 chr14:75592666 NEK9 -0.26 -4.52 -0.38 1.44e-5 Height; TGCT cis rs9527 0.590 rs7920868 chr10:104795409 C/T cg15744005 chr10:104629667 AS3MT -0.41 -4.8 -0.4 4.43e-6 Arsenic metabolism; TGCT cis rs7666738 0.830 rs1426666 chr4:99030887 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1005277 0.579 rs2504148 chr10:38400788 A/G cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs3806843 0.900 rs2563254 chr5:140142701 T/C cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs73198271 0.563 rs11783487 chr8:8541247 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.34 -5.51 -0.44 1.94e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12780845 0.505 rs973307 chr10:17246333 C/T cg01003015 chr10:17271136 VIM -0.51 -4.54 -0.38 1.3e-5 Homocysteine levels; TGCT cis rs7826238 0.653 rs2979202 chr8:8344127 T/C cg15556689 chr8:8085844 FLJ10661 0.59 5.53 0.44 1.79e-7 Systolic blood pressure; TGCT cis rs941408 1.000 rs1736176 chr19:2790394 G/A cg06609049 chr19:2785107 THOP1 0.78 7.74 0.57 3.06e-12 Total cholesterol levels; TGCT cis rs3845624 0.531 rs59012264 chr1:159251511 A/G cg12277145 chr1:160232707 DCAF8 -0.36 -4.44 -0.37 1.97e-5 Inflammatory biomarkers; TGCT cis rs1568889 1.000 rs12803716 chr11:28055111 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs2153535 0.580 rs9406163 chr6:8466642 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs12497850 0.865 rs7649458 chr3:48920127 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg16325326 chr1:53192061 ZYG11B 0.62 6.85 0.52 3.05e-10 Monocyte count; TGCT cis rs9914988 0.943 rs7217547 chr17:27106872 C/G cg20469991 chr17:27169893 C17orf63 -0.66 -5.03 -0.41 1.65e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7927592 0.731 rs11228288 chr11:68353550 A/G cg16797656 chr11:68205561 LRP5 0.25 4.5 0.37 1.53e-5 Total body bone mineral density; TGCT trans rs1005277 0.602 rs2504142 chr10:38383793 C/T cg17830980 chr10:43048298 ZNF37B -0.85 -10.98 -0.7 5.08e-20 Extrinsic epigenetic age acceleration; TGCT trans rs148330122 1 rs148330122 chr19:38520324 C/T cg12224730 chr15:35384648 NA 0.67 6.81 0.52 3.8e-10 Gut microbiota (bacterial taxa); TGCT cis rs9549367 0.789 rs71446682 chr13:113894908 A/G cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs1218582 0.772 rs10796935 chr1:154891363 G/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs3806843 0.868 rs2563281 chr5:140131219 T/A cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT trans rs561341 1.000 rs68140514 chr17:30335781 T/C cg20587970 chr11:113659929 NA -1.05 -13.14 -0.76 3.03e-25 Hip circumference adjusted for BMI; TGCT cis rs11098499 0.774 rs73842616 chr4:120290683 G/A cg09307838 chr4:120376055 NA 0.58 5.75 0.46 6.63e-8 Corneal astigmatism; TGCT cis rs7568458 0.870 rs1562323 chr2:85809711 T/C cg02493740 chr2:85810744 VAMP5 -0.29 -5.06 -0.41 1.49e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7666738 0.830 rs79075162 chr4:98960674 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg18252515 chr7:66147081 NA -1.13 -7.39 -0.55 1.94e-11 Diabetic kidney disease; TGCT cis rs2153535 0.580 rs7767780 chr6:8453462 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs2153535 0.601 rs2327091 chr6:8540369 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs7635838 0.819 rs12714866 chr3:11539058 C/T cg00170343 chr3:11313890 ATG7 0.68 6.36 0.5 3.46e-9 HDL cholesterol; TGCT cis rs6089584 0.888 rs2146853 chr20:60617908 A/T cg13665807 chr20:60559372 TAF4 -0.46 -5.0 -0.41 1.92e-6 Body mass index; TGCT cis rs35934224 0.783 rs34143881 chr22:19860093 A/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.04e-7 Glaucoma (primary open-angle); TGCT cis rs6684514 1.000 rs6684514 chr1:156255456 G/A cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1475911 0.744 rs12481958 chr21:43517269 A/G cg24372256 chr21:43528868 UMODL1;C21orf128 -0.27 -5.43 -0.44 2.89e-7 IgG glycosylation; TGCT cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg09177884 chr7:1199841 ZFAND2A -0.66 -6.91 -0.53 2.3e-10 Longevity;Endometriosis; TGCT cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs6701037 0.566 rs1883102 chr1:175136793 T/A cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs7647973 0.593 rs9870755 chr3:49809841 A/G cg05785598 chr3:49045655 WDR6 0.43 5.23 0.43 6.99e-7 Menarche (age at onset); TGCT cis rs9807841 0.670 rs2569512 chr19:10790162 A/G cg17848348 chr19:10766748 ILF3 -0.4 -4.58 -0.38 1.12e-5 Inflammatory skin disease; TGCT cis rs6688613 1.000 rs12130629 chr1:166953284 C/T cg07049167 chr1:166818506 POGK 0.21 4.52 0.38 1.43e-5 Refractive astigmatism; TGCT cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg07806771 chr7:64541737 NA 0.44 4.55 0.38 1.26e-5 Calcium levels; TGCT cis rs2404602 0.692 rs12902452 chr15:76921465 T/C cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.07e-6 Blood metabolite levels; TGCT cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg07061783 chr6:25882402 NA -0.55 -5.34 -0.43 4.34e-7 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs7677751 0.806 rs4864861 chr4:55097685 C/T cg17187183 chr4:55093834 PDGFRA 0.55 7.05 0.54 1.08e-10 Corneal astigmatism; TGCT cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4803468 0.901 rs3745292 chr19:41888506 A/G cg09537434 chr19:41945824 ATP5SL -0.88 -9.98 -0.67 1.4e-17 Height; TGCT cis rs7611238 0.538 rs4677833 chr3:195091449 G/T cg27323046 chr3:195102265 ACAP2 0.39 5.09 0.42 1.29e-6 Body mass index; TGCT cis rs67478160 0.643 rs6576005 chr14:104292369 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.35 -0.5 3.78e-9 Schizophrenia; TGCT cis rs9478217 1 rs9478217 chr6:151874122 A/G cg14416726 chr6:151773293 C6orf211;RMND1 0.52 4.48 0.37 1.68e-5 Total body bone mineral density (age 30-45); TGCT cis rs9911578 1.000 rs12947785 chr17:57045160 A/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs12908161 1.000 rs56864281 chr15:85357649 C/A cg11189052 chr15:85197271 WDR73 0.71 5.9 0.47 3.2e-8 Schizophrenia; TGCT cis rs751728 0.965 rs756137 chr6:33755890 T/C cg13859433 chr6:33739653 LEMD2 -0.43 -7.94 -0.58 1.04e-12 Crohn's disease; TGCT trans rs980000 0.557 rs3784611 chr15:60910223 C/G cg17159698 chr8:142842030 NA -0.81 -6.63 -0.51 9.42e-10 Menarche (age at onset); TGCT cis rs9611565 0.649 rs5758466 chr22:42176059 G/A cg17554472 chr22:41940697 POLR3H 0.43 4.61 0.38 9.67e-6 Vitiligo; TGCT cis rs7647973 0.626 rs2131108 chr3:49665390 C/T cg05785598 chr3:49045655 WDR6 0.43 5.34 0.43 4.37e-7 Menarche (age at onset); TGCT cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg16049864 chr8:95962084 TP53INP1 -0.73 -10.23 -0.68 3.4e-18 Type 2 diabetes; TGCT cis rs8180040 0.701 rs11130111 chr3:47009805 C/T cg27129171 chr3:47204927 SETD2 0.73 9.4 0.65 3.57e-16 Colorectal cancer; TGCT cis rs12477438 0.520 rs2516835 chr2:99779131 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs9894429 0.527 rs7405469 chr17:79566596 G/C cg21028142 chr17:79581711 NPLOC4 -0.27 -4.79 -0.39 4.75e-6 Eye color traits; TGCT cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg10047753 chr17:41438598 NA 0.95 9.5 0.65 2.09e-16 Menopause (age at onset); TGCT cis rs3806843 0.735 rs778596 chr5:140037272 G/A cg19875535 chr5:140030758 IK -0.36 -6.15 -0.48 9.57e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4891159 1.000 rs4891159 chr18:74101941 A/G cg24786174 chr18:74118243 ZNF516 0.52 7.21 0.54 4.72e-11 Longevity; TGCT cis rs6121246 0.567 rs6060262 chr20:30193071 A/C cg21427119 chr20:30132790 HM13 -0.38 -5.63 -0.45 1.14e-7 Mean corpuscular hemoglobin; TGCT cis rs10488031 0.557 rs13232698 chr7:37119973 G/A cg06458904 chr7:36312573 EEPD1 0.58 4.8 0.4 4.49e-6 QT interval; TGCT cis rs55692411 0.537 rs35375092 chr3:50065274 G/A cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs12044355 0.516 rs2356383 chr1:231742973 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.6 -4.76 -0.39 5.25e-6 Alzheimer's disease; TGCT cis rs7044106 0.537 rs10818474 chr9:123489964 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.52 0.51 1.59e-9 Hip circumference adjusted for BMI; TGCT cis rs6121246 0.567 rs6120890 chr20:30207659 T/G cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.39e-6 Mean corpuscular hemoglobin; TGCT cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg13695892 chr22:41940480 POLR3H -0.87 -8.08 -0.59 4.83e-13 Crohn's disease;Inflammatory bowel disease; TGCT trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg01516881 chr6:292596 DUSP22 -0.7 -7.47 -0.56 1.27e-11 Menopause (age at onset); TGCT cis rs3820928 0.874 rs3769646 chr2:227896330 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs12048904 0.619 rs10875346 chr1:101328083 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.91 8.36 0.6 1.07e-13 Multiple sclerosis; TGCT cis rs4319547 0.695 rs11058034 chr12:122894936 G/T cg08088222 chr12:122070432 ORAI1 -0.27 -4.62 -0.38 9.48e-6 Body mass index; TGCT cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg16145915 chr7:1198662 ZFAND2A -0.5 -6.19 -0.49 8.15e-9 Longevity;Endometriosis; TGCT cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg18305652 chr10:134549665 INPP5A 0.34 5.75 0.46 6.52e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs797680 0.856 rs7535628 chr1:93648728 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.81 -0.52 3.79e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs4072980 0.527 rs11210825 chr1:38446986 G/A cg26398791 chr1:38455867 SF3A3 -0.47 -4.56 -0.38 1.19e-5 Coronary artery disease; TGCT cis rs7085104 0.591 rs4919683 chr10:104585125 G/T cg15744005 chr10:104629667 AS3MT -0.45 -5.66 -0.45 9.88e-8 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs12477438 0.501 rs34272114 chr2:99737443 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs6940638 0.531 rs12211984 chr6:26986054 G/C cg02458000 chr6:26745757 NA 0.5 4.61 0.38 9.84e-6 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 6.94 0.53 1.91e-10 Prudent dietary pattern; TGCT cis rs6582630 0.555 rs11181053 chr12:38271364 T/C cg26384229 chr12:38710491 ALG10B -0.52 -4.6 -0.38 1.02e-5 Drug-induced liver injury (flucloxacillin); TGCT trans rs1814175 0.647 rs1404157 chr11:49917301 G/C cg15704280 chr7:45808275 SEPT13 -0.59 -6.82 -0.52 3.49e-10 Height; TGCT cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs10789491 1.000 rs1258061 chr1:47105000 G/A cg15501359 chr1:47185051 KIAA0494 -0.84 -8.4 -0.6 8.53e-14 Response to hepatitis C treatment; TGCT cis rs9916302 0.706 rs1877030 chr17:37740161 T/C cg07936489 chr17:37558343 FBXL20 -0.82 -5.57 -0.45 1.48e-7 Glomerular filtration rate (creatinine); TGCT cis rs1577917 0.958 rs2225754 chr6:86449698 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.35 -0.43 4.17e-7 Response to antipsychotic treatment; TGCT cis rs832540 0.866 rs832579 chr5:56164943 A/G cg24531977 chr5:56204891 C5orf35 -0.5 -5.09 -0.42 1.28e-6 Coronary artery disease; TGCT cis rs9733 0.503 rs7556451 chr1:150913142 A/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Tonsillectomy; TGCT cis rs853679 0.585 rs201000 chr6:27809159 C/T cg10876282 chr6:28092338 ZSCAN16 0.58 4.79 0.39 4.76e-6 Depression; TGCT cis rs7714584 1.000 rs73282234 chr5:150195924 G/C cg22134413 chr5:150180641 NA 1.17 8.69 0.62 1.76e-14 Crohn's disease; TGCT cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs950169 0.840 rs4842853 chr15:84942304 G/T cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs6671200 1.000 rs71654418 chr1:95662658 G/T cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg11644478 chr21:40555479 PSMG1 0.64 5.85 0.47 4.05e-8 Cognitive function; TGCT cis rs1609391 0.543 rs6800690 chr3:136623026 G/A cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs7264396 0.635 rs6058358 chr20:34492560 A/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.06 -0.41 1.47e-6 Total cholesterol levels; TGCT cis rs9549260 0.816 rs7337995 chr13:41249040 A/G cg21288729 chr13:41239152 FOXO1 0.97 10.0 0.67 1.24e-17 Red blood cell count; TGCT cis rs1580019 0.587 rs1597555 chr7:32546118 T/G cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.96 0.41 2.25e-6 Cognitive ability; TGCT cis rs2228479 0.850 rs57267516 chr16:89903552 G/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs4665809 0.652 rs7585891 chr2:26403766 G/A cg25036284 chr2:26402008 FAM59B -0.58 -4.61 -0.38 1.01e-5 Gut microbiome composition (summer); TGCT cis rs2549003 0.966 rs10072571 chr5:131816711 A/C cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs11190604 1.000 rs4919470 chr10:102298920 C/T cg16342193 chr10:102329863 NA -0.43 -5.3 -0.43 5.03e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7772486 0.875 rs2492855 chr6:146296926 A/G cg05347473 chr6:146136440 FBXO30 0.53 5.02 0.41 1.72e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs911555 0.855 rs2071408 chr14:103987078 G/A cg12935359 chr14:103987150 CKB 0.38 5.39 0.44 3.44e-7 Intelligence (multi-trait analysis); TGCT cis rs789859 0.897 rs1675923 chr3:194393208 A/G cg21106136 chr3:194405973 FAM43A -0.39 -5.16 -0.42 9.56e-7 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs35160687 0.901 rs7571424 chr2:86539160 A/G cg12542933 chr2:85804724 VAMP8 0.37 4.46 0.37 1.8e-5 Night sleep phenotypes; TGCT cis rs524281 0.817 rs10896092 chr11:65958046 A/C cg00563793 chr11:65837595 PACS1 0.52 4.57 0.38 1.18e-5 Electroencephalogram traits; TGCT cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg02073558 chr3:44770973 ZNF501 0.73 7.31 0.55 2.82e-11 Depressive symptoms; TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg01802117 chr1:53393560 SCP2 -0.43 -5.2 -0.42 7.91e-7 Monocyte count; TGCT cis rs10501293 0.746 rs7944392 chr11:43006672 T/G cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.2e-9 Cognitive performance; TGCT cis rs78456975 1.000 rs55761535 chr2:1561450 A/G cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs72949976 0.864 rs13389834 chr2:214025112 G/A cg08319019 chr2:214017104 IKZF2 -0.8 -7.47 -0.56 1.22e-11 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs56104184 0.615 rs73061693 chr19:49399941 C/A cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs8177253 0.896 rs34252038 chr3:133490621 G/T cg20276088 chr3:133502917 NA -0.24 -5.12 -0.42 1.15e-6 Iron status biomarkers; TGCT cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs8017423 0.845 rs80167706 chr14:90727629 G/C cg04374321 chr14:90722782 PSMC1 0.76 7.63 0.57 5.3e-12 Mortality in heart failure; TGCT cis rs7914558 1.000 rs7094843 chr10:104806654 A/C cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.67e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17376456 0.877 rs10059230 chr5:93450347 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs3771570 1.000 rs62193205 chr2:242316512 C/T cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs2243480 1.000 rs160652 chr7:65538431 A/G cg18252515 chr7:66147081 NA -1.13 -7.39 -0.55 1.94e-11 Diabetic kidney disease; TGCT cis rs10493773 0.532 rs1889919 chr1:86180034 A/G cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.2 -0.59 2.63e-13 Urate levels in overweight individuals; TGCT cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg23708337 chr7:1209742 NA 0.59 5.37 0.43 3.71e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.830 rs13124689 chr4:98961182 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs858239 0.601 rs1981665 chr7:23167969 T/C cg05602783 chr7:23145260 KLHL7 -0.65 -5.48 -0.44 2.32e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs185694 0.817 rs12874839 chr13:30891541 G/C cg07600127 chr13:30881527 KATNAL1 0.63 5.49 0.44 2.21e-7 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs7267979 0.844 rs6083824 chr20:25363057 G/A cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7731657 0.537 rs2097797 chr5:130355151 C/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs2629540 0.847 rs10901811 chr10:126417914 G/A cg08799069 chr10:126477246 METTL10 0.29 4.45 0.37 1.9e-5 Cocaine dependence; TGCT cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg24549020 chr5:56110836 MAP3K1 0.68 5.8 0.46 5.22e-8 Initial pursuit acceleration; TGCT cis rs2455799 0.533 rs2470513 chr3:15750056 G/A cg16303742 chr3:15540471 COLQ -0.26 -4.86 -0.4 3.48e-6 Mean platelet volume; TGCT cis rs9796 0.870 rs3101436 chr15:41287689 A/G cg18705301 chr15:41695430 NDUFAF1 0.41 5.3 0.43 5.07e-7 Menopause (age at onset); TGCT trans rs57221529 0.766 rs72706606 chr5:558609 T/C cg25482853 chr8:67687455 SGK3 1.2 10.16 0.67 5.25e-18 Lung disease severity in cystic fibrosis; TGCT cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs4664308 0.840 rs17218566 chr2:161054748 C/T cg03641300 chr2:160917029 PLA2R1 -0.27 -6.81 -0.52 3.82e-10 Idiopathic membranous nephropathy; TGCT cis rs7100689 0.577 rs873395 chr10:82037215 C/T cg01528321 chr10:82214614 TSPAN14 -0.71 -6.88 -0.53 2.56e-10 Post bronchodilator FEV1; TGCT cis rs28595532 0.920 rs116062544 chr4:119735548 G/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs1371867 0.846 rs2439458 chr8:101297984 T/C cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs12477438 0.520 rs11695751 chr2:99708247 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.26 0.77 1.59e-25 Chronic sinus infection; TGCT cis rs425277 0.583 rs3107151 chr1:2051513 T/G cg03732007 chr1:2071316 PRKCZ -0.26 -5.85 -0.46 4.16e-8 Height; TGCT cis rs9814567 1.000 rs2177601 chr3:134245434 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6964587 1.000 rs2269727 chr7:91752690 C/A cg17063962 chr7:91808500 NA 0.89 9.51 0.65 1.95e-16 Breast cancer; TGCT cis rs2836974 0.897 rs13052882 chr21:40555351 G/C cg11890956 chr21:40555474 PSMG1 1.15 12.32 0.74 2.88e-23 Cognitive function; TGCT cis rs7192750 0.586 rs12444829 chr16:71959727 A/G cg06353428 chr16:71660113 MARVELD3 0.82 7.38 0.55 2.03e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7267979 0.933 rs1130694 chr20:25276297 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1018836 0.923 rs12680211 chr8:91633434 C/T cg16814680 chr8:91681699 NA -0.84 -8.94 -0.63 4.67e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7149242 0.697 rs12882815 chr14:101183142 C/G cg11193865 chr14:101193038 DLK1 -0.49 -5.44 -0.44 2.74e-7 Platelet count; TGCT cis rs7439150 1.000 rs2227402 chr4:155486470 T/A cg22130008 chr4:155548532 NA -0.47 -5.8 -0.46 5.25e-8 Fibrinogen levels; TGCT cis rs669446 0.561 rs641351 chr1:44083519 G/A cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT trans rs877282 1.000 rs11253366 chr10:773386 C/T cg22713356 chr15:30763199 NA 1.15 10.1 0.67 7.07e-18 Uric acid levels; TGCT cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.84 0.46 4.3e-8 Bipolar disorder; TGCT cis rs7429990 0.932 rs11720151 chr3:48140634 G/A cg11946769 chr3:48343235 NME6 -0.55 -4.46 -0.37 1.81e-5 Educational attainment (years of education); TGCT cis rs2404602 0.716 rs1125932 chr15:76820540 C/T cg26408565 chr15:76604113 ETFA -0.37 -4.74 -0.39 5.83e-6 Blood metabolite levels; TGCT cis rs10791323 0.569 rs11223609 chr11:133741766 C/T cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs1775715 0.737 rs12256714 chr10:32216262 A/G cg14930904 chr10:32216787 ARHGAP12 -0.55 -5.31 -0.43 4.79e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6429082 0.749 rs3819974 chr1:235601958 G/T cg26050004 chr1:235667680 B3GALNT2 -0.56 -4.81 -0.4 4.22e-6 Adiposity; TGCT cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7044106 0.762 rs1158554 chr9:123400898 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.56 0.51 1.33e-9 Hip circumference adjusted for BMI; TGCT cis rs7552404 0.727 rs7547056 chr1:76279267 C/T cg10523679 chr1:76189770 ACADM 0.75 7.21 0.54 4.89e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs308403 0.506 rs309365 chr4:123659343 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.73 6.85 0.52 3e-10 Blood protein levels; TGCT cis rs9914988 0.943 rs4794836 chr17:27082710 C/G cg20469991 chr17:27169893 C17orf63 0.62 4.7 0.39 6.77e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7666738 0.830 rs13133355 chr4:98919415 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.02 0.41 1.78e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.967 rs373704 chr6:145860618 C/A cg23711669 chr6:146136114 FBXO30 0.71 6.66 0.51 7.78e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg03609598 chr5:56110824 MAP3K1 -0.62 -4.46 -0.37 1.82e-5 Type 2 diabetes; TGCT cis rs151997 1.000 rs27284 chr5:50198086 A/G cg06027927 chr5:50259733 NA 0.49 5.03 0.41 1.68e-6 Callous-unemotional behaviour; TGCT cis rs6088590 1.000 rs6119530 chr20:33403930 A/G cg24642439 chr20:33292090 TP53INP2 0.68 6.06 0.48 1.48e-8 Coronary artery disease; TGCT cis rs28595532 0.841 rs114155681 chr4:119736427 A/G cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg16558208 chr1:156270281 VHLL 0.27 4.83 0.4 3.87e-6 Tonsillectomy; TGCT cis rs1005224 0.853 rs61980778 chr14:76151532 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 0.67 5.96 0.47 2.45e-8 Large artery stroke; TGCT cis rs709400 0.663 rs62007683 chr14:103894071 G/T cg12935359 chr14:103987150 CKB -0.34 -4.9 -0.4 2.95e-6 Body mass index; TGCT cis rs7666738 0.830 rs4492007 chr4:98959848 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1580019 0.563 rs2392071 chr7:32572536 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.59 5.06 0.41 1.47e-6 Cognitive ability; TGCT cis rs137699 0.958 rs137705 chr22:39751394 T/C cg11247378 chr22:39784982 NA -0.44 -4.69 -0.39 7.08e-6 IgG glycosylation; TGCT cis rs3091242 0.806 rs35189848 chr1:25788422 A/G cg09222892 chr1:25734099 RHCE 0.4 6.43 0.5 2.46e-9 Erythrocyte sedimentation rate; TGCT cis rs208520 0.634 rs3909071 chr6:66836947 T/C cg07460842 chr6:66804631 NA -0.92 -9.51 -0.65 1.97e-16 Exhaled nitric oxide output; TGCT cis rs929354 0.772 rs6954050 chr7:156978554 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs2016266 0.859 rs10783575 chr12:53742885 C/T cg16917193 chr12:54089295 NA -0.6 -4.53 -0.38 1.34e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs7584330 0.554 rs3751110 chr2:238427142 T/C cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs2692947 0.683 rs1813381 chr2:96422939 C/T cg22654517 chr2:96458247 NA -0.23 -4.8 -0.4 4.44e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10791097 0.668 rs10791102 chr11:130744977 G/A cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3008870 0.959 rs2815353 chr1:67483372 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.08 11.47 0.72 3.32e-21 Lymphocyte percentage of white cells; TGCT cis rs11585357 0.895 rs112208664 chr1:17632010 G/A cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs12579753 0.879 rs7131927 chr12:82166313 T/C cg07988820 chr12:82153109 PPFIA2 -0.69 -7.77 -0.57 2.56e-12 Resting heart rate; TGCT cis rs854765 0.583 rs6502627 chr17:17849671 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.85 0.58 1.65e-12 Total body bone mineral density; TGCT cis rs12220238 1.000 rs10824085 chr10:75911984 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs17345786 0.906 rs58835747 chr3:101243634 T/C cg11279151 chr3:101281821 RG9MTD1 -0.42 -8.88 -0.62 6.33e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs2880765 0.545 rs17553734 chr15:86013059 C/G cg13263323 chr15:86062960 AKAP13 0.22 4.8 0.4 4.41e-6 Coronary artery disease; TGCT cis rs707040 1.000 rs2177672 chr2:155232079 C/G cg18104148 chr2:154337490 NA 0.19 4.57 0.38 1.17e-5 Sudden cardiac arrest; TGCT cis rs8078723 0.714 rs2241244 chr17:38153554 G/C cg17467752 chr17:38218738 THRA -0.55 -5.52 -0.44 1.93e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs2072499 0.966 rs887953 chr1:156191149 T/C cg06970220 chr1:156163860 SLC25A44 0.74 5.94 0.47 2.71e-8 Testicular germ cell tumor; TGCT cis rs7772486 0.654 rs6906402 chr6:146089307 C/G cg13319975 chr6:146136371 FBXO30 0.58 5.29 0.43 5.27e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs916888 0.773 rs199445 chr17:44817408 C/T cg07870213 chr5:140052090 DND1 0.65 7.75 0.57 2.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6840360 1.000 rs6535811 chr4:152598992 C/T cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg11502198 chr6:26597334 ABT1 0.54 4.95 0.41 2.42e-6 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg10150615 chr22:24372951 LOC391322 -0.71 -7.34 -0.55 2.5e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467773 0.933 rs2024970 chr6:26497520 T/A cg26531700 chr6:26746687 NA 0.58 5.5 0.44 2.07e-7 Intelligence (multi-trait analysis); TGCT trans rs7618501 1.000 rs6802890 chr3:49832261 A/G cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs7394190 0.748 rs11000775 chr10:75539010 T/C cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs526231 0.819 rs2288787 chr5:102600706 A/G cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs9650657 0.615 rs12541110 chr8:10695125 A/T cg16664915 chr8:10907788 XKR6 -0.29 -4.71 -0.39 6.47e-6 Neuroticism; TGCT trans rs7613875 0.600 rs1138536 chr3:50153356 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.82 8.44 0.6 6.82e-14 Body mass index; TGCT cis rs2729354 0.817 rs2467327 chr11:57279228 A/G cg24343310 chr11:57249947 NA 0.28 4.69 0.39 7.03e-6 Blood protein levels; TGCT cis rs12103 0.749 rs2649599 chr1:1305493 A/G cg16590012 chr1:1265354 TAS1R3 0.41 5.79 0.46 5.41e-8 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; TGCT cis rs539096 0.500 rs2527776 chr1:44345292 G/A cg13606994 chr1:44402422 ARTN -0.42 -4.52 -0.38 1.44e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.679 rs12679941 chr8:58051812 G/T cg08280861 chr8:58055591 NA 0.39 5.61 0.45 1.26e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs28761309 chr4:98867393 C/T cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs999943 0.846 rs1570760 chr6:33622933 C/T cg14003231 chr6:33640908 ITPR3 0.4 4.86 0.4 3.48e-6 Obesity (extreme); TGCT cis rs3096299 0.967 rs3102341 chr16:89450744 G/A cg06640241 chr16:89574553 SPG7 0.69 6.77 0.52 4.56e-10 Multiple myeloma (IgH translocation); TGCT cis rs853679 0.527 rs853690 chr6:28285482 G/A cg18815343 chr6:28367644 ZSCAN12 -0.47 -4.87 -0.4 3.32e-6 Depression; TGCT cis rs2067615 0.579 rs3910854 chr12:107165669 T/C cg15890332 chr12:107067104 RFX4 0.29 5.63 0.45 1.15e-7 Heart rate; TGCT cis rs9653442 0.527 rs2164712 chr2:100745404 C/G cg22139774 chr2:100720529 AFF3 -0.38 -5.61 -0.45 1.23e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs77106637 0.769 rs11603313 chr11:72588177 G/A cg03713592 chr11:72463424 ARAP1 0.9 6.14 0.48 1.05e-8 Type 2 diabetes; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg12419862 chr22:24373484 LOC391322 -0.79 -8.14 -0.59 3.55e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg11301795 chr4:187892539 NA -0.34 -5.26 -0.43 6.21e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.861 rs57314710 chr8:58196051 T/C cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs6952808 0.760 rs11764960 chr7:1950532 G/A cg04267008 chr7:1944627 MAD1L1 -0.37 -4.87 -0.4 3.39e-6 Bipolar disorder and schizophrenia; TGCT cis rs1997103 1.000 rs9649857 chr7:55411777 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6977660 0.714 rs10260866 chr7:19793151 T/C cg05791153 chr7:19748676 TWISTNB 0.88 5.05 0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs6570726 0.791 rs6913727 chr6:145899826 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4851266 0.898 rs13026143 chr2:100865406 A/G cg22139774 chr2:100720529 AFF3 0.3 4.54 0.38 1.31e-5 Educational attainment; TGCT cis rs8028182 0.636 rs4886715 chr15:75831449 C/T cg20655648 chr15:75932815 IMP3 0.58 4.61 0.38 1e-5 Sudden cardiac arrest; TGCT trans rs2469997 1.000 rs2469997 chr8:120353267 C/G cg01792902 chr3:178864926 PIK3CA -0.8 -6.64 -0.51 8.76e-10 Hypertension (SNP x SNP interaction); TGCT cis rs9462846 0.691 rs67059212 chr6:42913269 T/G cg13397359 chr6:42928475 GNMT 0.6 4.59 0.38 1.06e-5 Blood protein levels; TGCT cis rs17376456 0.597 rs7733142 chr5:93322795 C/A cg09848695 chr5:92956644 FAM172A;MIR2277 -0.53 -4.48 -0.37 1.68e-5 Diabetic retinopathy; TGCT cis rs2303745 0.589 rs1465576 chr19:17398487 G/A cg04248312 chr19:17393744 ANKLE1 -0.34 -5.54 -0.45 1.72e-7 Systemic lupus erythematosus; TGCT cis rs78456975 0.527 rs72778003 chr2:1571487 G/A cg12573674 chr2:1569213 NA -0.48 -5.0 -0.41 1.91e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs1218582 0.741 rs10908447 chr1:154869742 C/T cg16680214 chr1:154839983 KCNN3 -0.42 -9.25 -0.64 8.37e-16 Prostate cancer; TGCT cis rs2354432 0.607 rs4950385 chr1:146656292 A/G cg25205988 chr1:146714368 CHD1L 1.34 6.29 0.49 4.92e-9 Mitochondrial DNA levels; TGCT cis rs1577917 1.000 rs10455158 chr6:86672825 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.48 -0.44 2.27e-7 Response to antipsychotic treatment; TGCT cis rs9372498 0.536 rs9481825 chr6:118876092 C/T cg07617317 chr6:118971624 C6orf204 0.5 5.42 0.44 3.03e-7 Diastolic blood pressure; TGCT cis rs1801251 1.000 rs11555646 chr2:233599904 A/C cg08000102 chr2:233561755 GIGYF2 0.63 6.35 0.5 3.77e-9 Coronary artery disease; TGCT cis rs9611519 0.603 rs9607764 chr22:41411804 G/C cg03806693 chr22:41940476 POLR3H -0.64 -6.08 -0.48 1.36e-8 Neuroticism; TGCT cis rs1577917 1.000 rs12212733 chr6:86726013 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg02953382 chr22:24373134 LOC391322 0.82 7.01 0.53 1.37e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2172802 0.924 rs10018746 chr4:62445246 T/C cg04118610 chr4:62707027 LPHN3 -0.39 -4.53 -0.38 1.39e-5 Partial epilepsies; TGCT cis rs769267 1.000 rs2301669 chr19:19453560 C/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs6866344 0.697 rs62392833 chr5:178135452 T/A cg10224037 chr5:178157518 ZNF354A 0.92 8.04 0.59 6.16e-13 Neutrophil percentage of white cells; TGCT cis rs6752107 0.935 rs10929326 chr2:234151045 T/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.88 0.4 3.13e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1401999 1.000 rs869417 chr3:183689138 T/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs4638749 0.953 rs4676033 chr2:108869368 G/A cg06795125 chr2:108905320 SULT1C2 -0.36 -4.55 -0.38 1.25e-5 Blood pressure; TGCT cis rs7412746 0.611 rs16827671 chr1:150738759 T/C cg09365446 chr1:150670422 GOLPH3L 0.33 4.75 0.39 5.64e-6 Melanoma; TGCT cis rs7267979 0.966 rs6083855 chr20:25405118 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7209700 0.889 rs11079769 chr17:45349731 A/T cg17185639 chr17:45330862 ITGB3 0.19 4.83 0.4 3.98e-6 IgG glycosylation; TGCT cis rs9467711 0.606 rs9379858 chr6:26367689 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs28735056 1.000 rs56376220 chr18:77609462 C/T cg05926928 chr17:57297772 GDPD1 -0.7 -7.71 -0.57 3.52e-12 Schizophrenia; TGCT cis rs2797160 0.651 rs1343121 chr6:126036184 C/T cg05901451 chr6:126070800 HEY2 0.77 6.91 0.53 2.27e-10 Endometrial cancer; TGCT cis rs514406 0.825 rs6695819 chr1:53223366 T/C cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.29e-11 Monocyte count; TGCT cis rs981844 0.890 rs55917677 chr4:154701051 C/T cg14289246 chr4:154710475 SFRP2 1.05 9.32 0.64 5.44e-16 Response to statins (LDL cholesterol change); TGCT cis rs7043114 0.525 rs9299404 chr9:95170338 A/G cg14631576 chr9:95140430 CENPP 0.28 4.64 0.38 8.9e-6 Height; TGCT cis rs7584330 0.697 rs60278044 chr2:238357118 A/G cg14458575 chr2:238380390 NA 0.52 7.84 0.58 1.79e-12 Prostate cancer; TGCT cis rs6684514 1.000 rs10494304 chr1:156285764 C/G cg20302342 chr1:156215951 PAQR6 -0.35 -4.74 -0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg06238570 chr21:40685208 BRWD1 -0.83 -8.83 -0.62 8.44e-15 Cognitive function; TGCT cis rs12220238 0.722 rs12360087 chr10:76373904 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.67 5.11 0.42 1.17e-6 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg12667521 chr19:29218732 NA 0.54 5.72 0.46 7.65e-8 Methadone dose in opioid dependence; TGCT cis rs10504229 0.679 rs12375285 chr8:58040084 G/A cg11062466 chr8:58055876 NA 0.34 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs758747 0.531 rs13332500 chr16:3575270 A/C cg07396092 chr16:3662230 BTBD12 0.53 4.75 0.39 5.6e-6 Body mass index; TGCT cis rs12497850 0.931 rs4974080 chr3:49030828 A/C cg07636037 chr3:49044803 WDR6 0.96 10.59 0.69 4.61e-19 Parkinson's disease; TGCT cis rs2046867 0.818 rs17690720 chr3:72866030 T/C cg25664220 chr3:72788482 NA -0.56 -7.04 -0.53 1.16e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9473924 1.000 rs9473932 chr6:50857995 G/A cg14470998 chr6:50812995 TFAP2B 0.61 4.48 0.37 1.7e-5 Body mass index; TGCT cis rs854765 0.663 rs1108648 chr17:17750558 G/A cg04398451 chr17:18023971 MYO15A 0.3 4.59 0.38 1.09e-5 Total body bone mineral density; TGCT cis rs9818758 0.556 rs9835439 chr3:49220330 G/C cg00383909 chr3:49044727 WDR6 1.26 6.33 0.49 4.1e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7017914 0.967 rs13261712 chr8:71732264 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs40363 0.645 rs250630 chr16:3524242 C/T cg00484396 chr16:3507460 NAT15 0.43 6.52 0.51 1.62e-9 Tuberculosis; TGCT cis rs36051895 0.658 rs62541531 chr9:5011795 C/T cg02405213 chr9:5042618 JAK2 -0.8 -11.07 -0.7 3.18e-20 Pediatric autoimmune diseases; TGCT cis rs6089584 0.566 rs11699442 chr20:60623268 A/G cg13770153 chr20:60521292 NA -0.4 -4.85 -0.4 3.65e-6 Body mass index; TGCT cis rs9653442 0.527 rs2118280 chr2:100746395 G/A cg07810366 chr2:100720526 AFF3 -0.37 -5.2 -0.42 8.01e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs360798 0.532 rs2136737 chr2:62969310 G/C cg17519650 chr2:63277830 OTX1 -0.55 -4.66 -0.39 8.12e-6 Coronary artery disease; TGCT cis rs10791323 0.604 rs2723615 chr11:133704567 C/T cg15485101 chr11:133734466 NA 0.42 5.29 0.43 5.28e-7 Childhood ear infection; TGCT trans rs208520 0.690 rs1738970 chr6:66809491 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.61 -0.69 4.11e-19 Exhaled nitric oxide output; TGCT cis rs6740322 0.841 rs10211126 chr2:43551416 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.77 -0.52 4.47e-10 Coronary artery disease; TGCT cis rs925228 0.504 rs7568272 chr2:24313785 T/C cg01493198 chr2:24299560 SF3B14 0.73 4.75 0.39 5.43e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs6964587 0.934 rs6973792 chr7:91749798 C/A cg17063962 chr7:91808500 NA 0.88 9.42 0.65 3.2e-16 Breast cancer; TGCT cis rs910316 0.737 rs175072 chr14:75502827 T/C cg11812906 chr14:75593930 NEK9 -0.58 -5.52 -0.44 1.92e-7 Height; TGCT cis rs11626933 1.000 rs3825661 chr14:90767607 C/T cg14092571 chr14:90743983 NA 0.32 6.73 0.52 5.73e-10 Gut microbiota (bacterial taxa); TGCT cis rs1153858 1.000 rs12593370 chr15:45617417 C/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.66 0.45 9.96e-8 Homoarginine levels; TGCT cis rs2060793 0.712 rs11023310 chr11:14725263 T/G cg00085434 chr11:14927489 NA 0.34 4.68 0.39 7.45e-6 Vitamin D levels; TGCT cis rs637571 0.522 rs566590 chr11:65754062 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.65 6.38 0.5 3.14e-9 Eosinophil percentage of white cells; TGCT cis rs826838 0.967 rs826855 chr12:39114888 T/C cg13010199 chr12:38710504 ALG10B -0.64 -5.07 -0.41 1.39e-6 Heart rate; TGCT cis rs42648 0.837 rs42615 chr7:89950501 G/T cg25739043 chr7:89950458 NA -0.73 -7.29 -0.55 3.2e-11 Homocysteine levels; TGCT cis rs2115630 0.967 rs12595786 chr15:85336670 T/C cg11189052 chr15:85197271 WDR73 -0.59 -5.56 -0.45 1.59e-7 P wave terminal force; TGCT cis rs6940638 0.688 rs9393790 chr6:27114052 A/C cg15659132 chr6:26577336 NA 0.52 4.6 0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg08280861 chr8:58055591 NA 0.47 5.28 0.43 5.6e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467711 0.606 rs9379856 chr6:26366836 A/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12142240 0.698 rs6684274 chr1:46810842 A/G cg00530320 chr1:46809349 NSUN4 -0.3 -6.32 -0.49 4.24e-9 Menopause (age at onset); TGCT cis rs7119038 0.818 rs11826521 chr11:118610549 G/T cg19308663 chr11:118741387 NA 0.28 5.25 0.43 6.5e-7 Sjögren's syndrome; TGCT cis rs5750830 0.649 rs5757657 chr22:39798429 G/T cg24399712 chr22:39784796 NA -1.07 -13.49 -0.77 4.49e-26 Intelligence (multi-trait analysis); TGCT cis rs13118159 0.872 rs4974604 chr4:1345798 T/C cg22683308 chr4:1340831 KIAA1530 -0.65 -6.14 -0.48 1.02e-8 Longevity; TGCT cis rs4253772 0.550 rs738444 chr22:46721088 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.69 5.31 0.43 4.82e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9325144 0.650 rs6582631 chr12:38744135 T/C cg26384229 chr12:38710491 ALG10B 0.61 5.61 0.45 1.26e-7 Morning vs. evening chronotype; TGCT cis rs6089829 0.888 rs4809268 chr20:61675249 C/G cg03213289 chr20:61660250 NA 0.72 9.45 0.65 2.69e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7568458 0.846 rs2028900 chr2:85767735 A/G cg17127132 chr2:85788382 GGCX -0.67 -6.29 -0.49 5.04e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs11785400 0.793 rs4336593 chr8:143739647 A/C cg24634471 chr8:143751801 JRK -0.56 -5.7 -0.46 8.27e-8 Schizophrenia; TGCT cis rs6912958 0.559 rs376633 chr6:88042785 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.48 6.35 0.5 3.65e-9 Monocyte percentage of white cells; TGCT cis rs12681287 0.927 rs2953517 chr8:87332013 C/T cg27223183 chr8:87520930 FAM82B -0.88 -6.82 -0.52 3.62e-10 Caudate activity during reward; TGCT cis rs6860806 0.507 rs183898 chr5:131716902 C/G cg24060327 chr5:131705240 SLC22A5 0.78 8.53 0.61 4.27e-14 Breast cancer; TGCT cis rs4851266 1.000 rs7566527 chr2:100811970 C/T cg07810366 chr2:100720526 AFF3 -0.37 -5.3 -0.43 5.04e-7 Educational attainment; TGCT cis rs10504229 0.871 rs56372514 chr8:58157166 A/G cg22535103 chr8:58192502 C8orf71 -0.39 -4.73 -0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs11673344 0.504 rs35162188 chr19:37579810 G/A cg08039142 chr19:36980659 ZNF566 0.5 4.6 0.38 1.02e-5 Obesity-related traits; TGCT cis rs26868 0.742 rs26848 chr16:2263516 A/G cg07762234 chr16:2261099 C16orf79 -0.29 -5.19 -0.42 8.36e-7 Height; TGCT cis rs12368653 0.591 rs1552842 chr12:58012163 A/G cg12615879 chr12:58013172 SLC26A10 -0.52 -6.24 -0.49 6.47e-9 Multiple sclerosis; TGCT cis rs76878669 0.561 rs2279861 chr11:66133336 A/G cg18002602 chr11:66138449 SLC29A2 0.54 6.62 0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.59 5.79 0.46 5.36e-8 Bipolar disorder; TGCT cis rs9308731 0.583 rs2165107 chr2:111931350 C/G cg04202892 chr2:111875749 ACOXL 0.46 5.14 0.42 1.02e-6 Chronic lymphocytic leukemia; TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs1670533 1.000 rs13135215 chr4:1054364 A/G cg27284194 chr4:1044797 NA 0.69 5.71 0.46 7.76e-8 Recombination rate (females); TGCT cis rs6500550 0.597 rs2285814 chr16:3565123 G/T cg07396092 chr16:3662230 BTBD12 0.53 4.72 0.39 6.24e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;White blood cell count;Neutrophil count; TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs3806843 0.735 rs702394 chr5:140086786 A/G cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs17253792 0.822 rs17685102 chr14:56129214 A/G cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs476633 0.691 rs28568756 chr15:41539371 G/A cg18705301 chr15:41695430 NDUFAF1 -0.55 -7.43 -0.56 1.54e-11 Glomerular filtration rate (creatinine); TGCT cis rs9486719 1.000 rs12191653 chr6:96903898 T/C cg18709589 chr6:96969512 KIAA0776 -0.68 -5.05 -0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs295137 0.836 rs10804097 chr2:201104924 A/T cg23649088 chr2:200775458 C2orf69 0.34 5.82 0.46 4.79e-8 Asthma (bronchodilator response); TGCT cis rs752092 0.925 rs8032007 chr15:101790817 C/T cg25114630 chr15:101792522 CHSY1 -0.53 -5.1 -0.42 1.22e-6 Corneal structure; TGCT cis rs3806843 0.576 rs155361 chr5:140307284 G/A cg09824255 chr5:140014002 CD14 0.25 4.59 0.38 1.09e-5 Depressive symptoms (multi-trait analysis); TGCT trans rs797680 0.786 rs555161 chr1:93676314 A/G cg27528825 chr2:159282178 CCDC148 -0.35 -6.88 -0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs16910800 0.731 rs59845980 chr11:23191511 T/G cg20040320 chr11:23191996 NA -0.51 -4.47 -0.37 1.71e-5 Cancer; TGCT cis rs17401966 0.838 rs4846207 chr1:10313811 T/C cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg00080972 chr5:178986291 RUFY1 -0.57 -7.22 -0.54 4.63e-11 Lung cancer; TGCT cis rs950169 0.920 rs2135551 chr15:84707851 A/G cg11189052 chr15:85197271 WDR73 0.7 5.94 0.47 2.64e-8 Schizophrenia; TGCT trans rs877282 0.853 rs12777155 chr10:754731 G/C cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg10263370 chr3:44754102 ZNF502 -0.45 -5.35 -0.43 4.08e-7 Depressive symptoms; TGCT cis rs734999 0.545 rs10910105 chr1:2538209 G/A cg18854424 chr1:2615690 NA 0.41 4.58 0.38 1.13e-5 Ulcerative colitis; TGCT cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg03303774 chr4:1407052 NA 0.31 4.96 0.41 2.25e-6 Obesity-related traits; TGCT cis rs12541335 0.639 rs35068739 chr8:22201719 T/C cg18135555 chr8:22132992 PIWIL2 0.3 6.09 0.48 1.29e-8 Hypertriglyceridemia; TGCT cis rs1552244 1.000 rs12152515 chr3:10143976 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.87 -0.53 2.72e-10 Alzheimer's disease; TGCT trans rs2727020 0.658 rs10839269 chr11:49385596 A/G cg15704280 chr7:45808275 SEPT13 -0.74 -8.25 -0.6 1.97e-13 Coronary artery disease; TGCT cis rs7829975 0.688 rs6995407 chr8:8384647 C/G cg08975724 chr8:8085496 FLJ10661 0.64 5.92 0.47 2.89e-8 Mood instability; TGCT cis rs4319547 0.585 rs7953007 chr12:122816977 A/C cg08088222 chr12:122070432 ORAI1 0.26 4.69 0.39 7.14e-6 Body mass index; TGCT cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs2033711 0.905 rs1077420 chr19:58968875 A/C cg12042659 chr19:58951599 ZNF132 0.56 4.99 0.41 2.03e-6 Uric acid clearance; TGCT cis rs2228479 0.850 rs17226980 chr16:89825065 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs6121246 0.529 rs6060134 chr20:30176794 A/G cg18721089 chr20:30220636 NA -0.63 -6.86 -0.52 2.95e-10 Mean corpuscular hemoglobin; TGCT cis rs3020736 0.500 rs6002616 chr22:42504679 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs933688 1.000 rs1541674 chr5:90660447 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 10.13 0.67 6.16e-18 Smoking behavior; TGCT cis rs7949030 0.596 rs11231138 chr11:62316195 C/G cg11742103 chr11:62369870 EML3;MTA2 0.6 8.45 0.6 6.5e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9811920 0.715 rs6810262 chr3:99906342 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.39 -4.57 -0.38 1.17e-5 Axial length; TGCT cis rs7208859 0.562 rs216408 chr17:28907757 C/G cg19761014 chr17:28927070 LRRC37B2 -0.54 -4.67 -0.39 7.61e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs796364 0.694 rs1653299 chr2:201075611 A/G cg23649088 chr2:200775458 C2orf69 0.33 4.77 0.39 5.01e-6 Schizophrenia; TGCT cis rs986417 0.901 rs1007152 chr14:60999493 C/T cg27398547 chr14:60952738 C14orf39 1.49 10.78 0.7 1.64e-19 Gut microbiota (bacterial taxa); TGCT cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs10540 0.908 rs35608427 chr11:498976 T/C cg03934478 chr11:495069 RNH1 0.35 5.82 0.46 4.66e-8 Body mass index; TGCT trans rs629535 0.862 rs662725 chr8:70029616 C/T cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs72843506 0.722 rs9897168 chr17:20034274 T/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.87 -0.4 3.33e-6 Schizophrenia; TGCT cis rs9913156 0.793 rs55677157 chr17:4576620 C/T cg00122941 chr17:4613640 ARRB2 0.88 6.88 0.53 2.6200000000000003e-10 Lymphocyte counts; TGCT cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs72843506 0.652 rs28550747 chr17:20178312 A/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.93 -0.4 2.61e-6 Schizophrenia; TGCT cis rs77669868 0.929 rs76761091 chr11:114067058 A/G cg01914181 chr11:114070210 ZBTB16 0.34 5.72 0.46 7.53e-8 Monocyte percentage of white cells; TGCT cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg23758822 chr17:41437982 NA 0.72 6.99 0.53 1.51e-10 Menopause (age at onset); TGCT cis rs826838 0.616 rs4418873 chr12:38625473 C/A cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Heart rate; TGCT cis rs797680 0.822 rs1057257 chr1:93621483 A/G cg17826107 chr1:92977322 EVI5 -0.24 -5.19 -0.42 8.19e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7674212 0.507 rs223361 chr4:103769304 T/C cg16532752 chr4:104119610 CENPE -0.62 -5.59 -0.45 1.41e-7 Type 2 diabetes; TGCT cis rs950169 0.922 rs17531523 chr15:85132449 C/G cg12863693 chr15:85201151 NMB 0.39 4.44 0.37 1.98e-5 Schizophrenia; TGCT cis rs769267 0.930 rs4808965 chr19:19631655 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs9682041 0.696 rs6774380 chr3:170091644 T/A cg11886554 chr3:170076028 SKIL 0.61 4.78 0.39 4.77e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs910316 1.000 rs175426 chr14:75624134 C/T cg11812906 chr14:75593930 NEK9 -0.74 -7.23 -0.54 4.25e-11 Height; TGCT cis rs875971 0.642 rs35526611 chr7:66094008 C/T cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs3809566 0.963 rs4775608 chr15:63331940 A/G cg00520135 chr15:63333846 TPM1 -0.44 -5.46 -0.44 2.44e-7 Platelet count; TGCT cis rs2637266 0.935 rs12259550 chr10:78352843 A/G cg18941641 chr10:78392320 NA 0.42 5.2 0.42 8.09e-7 Pulmonary function; TGCT cis rs79057730 0.599 rs6951032 chr7:794092 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.68 5.55 0.45 1.67e-7 Initial pursuit acceleration; TGCT cis rs912057 0.833 rs1294424 chr6:6744135 G/A cg06612196 chr6:6737390 NA 0.37 4.88 0.4 3.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.99 0.47 2.09e-8 Bipolar disorder; TGCT cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg12516959 chr21:47718080 NA 0.33 4.89 0.4 3.07e-6 Testicular germ cell tumor; TGCT cis rs727563 0.580 rs202626 chr22:41847190 C/A cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs13191362 1.000 rs35126854 chr6:163012443 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11031096 0.516 rs7113845 chr11:3989226 C/G cg18678763 chr11:4115507 RRM1 -0.42 -5.14 -0.42 1.04e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4819052 0.851 rs914214 chr21:46697820 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.830 rs10856936 chr4:99011319 T/C cg18180107 chr4:99064573 C4orf37 0.52 4.85 0.4 3.57e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3806843 0.548 rs246038 chr5:140331699 A/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs911555 0.713 rs1107070 chr14:103970508 G/T cg12935359 chr14:103987150 CKB 0.33 4.47 0.37 1.73e-5 Intelligence (multi-trait analysis); TGCT cis rs514406 0.505 rs387436 chr1:53179376 C/T cg08859206 chr1:53392774 SCP2 0.36 5.23 0.42 7.05e-7 Monocyte count; TGCT cis rs6762 0.642 rs28692469 chr11:839675 T/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.45 -4.5 -0.37 1.53e-5 Mean platelet volume; TGCT cis rs172166 0.560 rs203878 chr6:28048996 T/G cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.71 -0.39 6.43e-6 Cardiac Troponin-T levels; TGCT cis rs11096990 0.656 rs2066788 chr4:39301605 G/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.52 -0.38 1.43e-5 Cognitive function; TGCT cis rs9467711 0.790 rs1979 chr6:26377591 G/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs13315871 1.000 rs71311869 chr3:58398922 C/T cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs3796352 1.000 rs11713859 chr3:53042080 C/A cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs933688 1.000 rs10058025 chr5:90689052 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.15 0.59 3.39e-13 Smoking behavior; TGCT cis rs7565124 1.000 rs60676431 chr2:20263863 G/A cg00462460 chr2:20212509 MATN3 -0.43 -4.64 -0.38 8.68e-6 Major depressive disorder; TGCT cis rs10791097 0.694 rs4936123 chr11:130740967 G/A cg05962950 chr11:130786565 SNX19 0.9 11.18 0.71 1.72e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12477438 0.520 rs7572660 chr2:99788582 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.02 11.79 0.73 5.47e-22 Chronic sinus infection; TGCT cis rs4273100 0.646 rs4924987 chr17:19247075 G/A cg03910582 chr17:19030146 GRAPL -0.51 -6.21 -0.49 7.47e-9 Schizophrenia; TGCT trans rs797680 0.821 rs7551485 chr1:93751280 G/A cg27528825 chr2:159282178 CCDC148 0.34 6.71 0.52 6.32e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs10510102 0.872 rs7916008 chr10:123703093 A/G cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs2224391 0.628 rs2753231 chr6:5248915 C/A cg09085698 chr6:5261316 LYRM4;FARS2 -0.98 -6.21 -0.49 7.43e-9 Height; TGCT cis rs35306767 0.903 rs12769002 chr10:927666 C/G cg20503657 chr10:835505 NA -0.8 -11.26 -0.71 1.05e-20 Eosinophil percentage of granulocytes; TGCT cis rs734999 0.505 rs4648659 chr1:2560903 T/G cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs6582630 0.555 rs10785443 chr12:38463792 A/C cg26384229 chr12:38710491 ALG10B 0.82 7.5 0.56 1.09e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs6089584 0.507 rs6061990 chr20:60628429 T/G cg06108461 chr20:60628389 TAF4 -0.41 -5.11 -0.42 1.2e-6 Body mass index; TGCT cis rs7772486 0.754 rs857881 chr6:145970793 C/A cg13319975 chr6:146136371 FBXO30 0.56 4.97 0.41 2.22e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs910316 1.000 rs3742780 chr14:75505008 G/C cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.97e-11 Height; TGCT cis rs7172809 0.573 rs11854466 chr15:77584733 T/C cg22256960 chr15:77711686 NA -0.47 -4.61 -0.38 9.99e-6 Glucose homeostasis traits; TGCT cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg06238570 chr21:40685208 BRWD1 0.79 8.66 0.61 2.14e-14 Cognitive function; TGCT cis rs6964587 0.839 rs13229273 chr7:91444472 G/A cg17063962 chr7:91808500 NA 0.83 8.41 0.6 8.35e-14 Breast cancer; TGCT cis rs986417 1.000 rs713336 chr14:60974958 T/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs1163251 0.869 rs487884 chr1:120217330 C/T cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.55 5.08 0.42 1.34e-6 Bipolar disorder; TGCT cis rs11578119 0.933 rs12124515 chr1:170452501 C/T cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs7727544 0.716 rs10058655 chr5:131570896 A/T cg24060327 chr5:131705240 SLC22A5 -0.55 -5.23 -0.42 7.13e-7 Blood metabolite levels; TGCT cis rs765787 0.530 rs1648286 chr15:45517386 G/C cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs11096990 0.634 rs7564 chr4:39287322 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.46e-5 Cognitive function; TGCT cis rs6998277 1.000 rs62523306 chr8:103640752 C/A cg10187029 chr8:103597600 NA 0.47 5.91 0.47 3.05e-8 Migraine; TGCT cis rs8177253 0.931 rs8177256 chr3:133480276 G/T cg01448562 chr3:133502909 NA -0.33 -6.71 -0.52 6.3e-10 Iron status biomarkers; TGCT cis rs17076896 0.609 rs77801871 chr13:19929336 A/G cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs9322193 0.923 rs9800614 chr6:149965740 G/A cg13206674 chr6:150067644 NUP43 0.51 4.45 0.37 1.91e-5 Lung cancer; TGCT cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg18867708 chr6:26865862 GUSBL1 -0.39 -5.16 -0.42 9.66e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs734999 0.967 rs2495365 chr1:2498027 A/G cg18854424 chr1:2615690 NA 0.47 5.78 0.46 5.71e-8 Ulcerative colitis; TGCT cis rs4808199 1.000 rs4808199 chr19:19545099 C/T cg03709012 chr19:19516395 GATAD2A 0.97 7.64 0.57 5.05e-12 Nonalcoholic fatty liver disease; TGCT cis rs916888 0.821 rs199525 chr17:44847834 T/G cg16520312 chr17:43971471 MAPT;LOC100128977 -0.6 -5.38 -0.43 3.65e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9976767 0.637 rs11909930 chr21:43822200 C/A cg23042151 chr21:43824109 UBASH3A -0.22 -4.75 -0.39 5.46e-6 Type 1 diabetes; TGCT cis rs7267979 1.000 rs6107047 chr20:25442097 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4595586 0.545 rs12816546 chr12:39398913 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7937682 0.632 rs11823089 chr11:111673539 A/G cg09085632 chr11:111637200 PPP2R1B 0.81 7.16 0.54 6.29e-11 Primary sclerosing cholangitis; TGCT cis rs6138458 0.626 rs6050259 chr20:25011423 A/G cg26195577 chr20:24973756 C20orf3 0.99 9.24 0.64 8.46e-16 Blood protein levels; TGCT cis rs72843506 0.591 rs117720402 chr17:20347611 C/T cg18052601 chr17:19850474 AKAP10 0.28 4.6 0.38 1.02e-5 Schizophrenia; TGCT cis rs7412746 0.611 rs72704679 chr1:150897477 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs11971779 0.818 rs12056045 chr7:139025430 C/G cg07862535 chr7:139043722 LUC7L2 0.76 5.74 0.46 6.98e-8 Diisocyanate-induced asthma; TGCT cis rs600231 0.708 rs3132767 chr11:65234860 C/T cg17120908 chr11:65337727 SSSCA1 -0.55 -5.16 -0.42 9.53e-7 Bone mineral density; TGCT cis rs2302045 1.000 rs2240539 chr2:242035544 G/C cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs853679 0.546 rs200949 chr6:27835435 A/G cg08798685 chr6:27730294 NA -0.34 -4.69 -0.39 7.2e-6 Depression; TGCT cis rs7829975 0.714 rs6994038 chr8:8660538 C/A cg06636001 chr8:8085503 FLJ10661 0.68 6.01 0.47 1.94e-8 Mood instability; TGCT cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg24531977 chr5:56204891 C5orf35 -0.74 -7.14 -0.54 7.06e-11 Initial pursuit acceleration; TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg22166914 chr1:53195759 ZYG11B 0.38 6.18 0.49 8.32e-9 Monocyte count; TGCT cis rs12549025 0.536 rs9644077 chr8:23360332 C/T cg00472375 chr8:23315376 ENTPD4 0.67 5.23 0.42 7.07e-7 Reticulocyte fraction of red cells; TGCT cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3771570 0.901 rs10190033 chr2:242412358 A/C cg21155796 chr2:242212141 HDLBP 0.89 6.86 0.52 2.88e-10 Prostate cancer; TGCT cis rs4689388 0.926 rs11725500 chr4:6293919 C/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs1814175 0.754 rs10219245 chr11:49645052 C/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.64 -0.61 2.33e-14 Height; TGCT cis rs7811142 1.000 rs11559117 chr7:100076614 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs9952991 0.883 rs2542147 chr18:12775851 G/T cg09945482 chr18:12777974 NA 0.5 4.75 0.39 5.61e-6 Inflammatory skin disease; TGCT cis rs10875595 0.836 rs758346 chr5:140674734 C/A cg24830062 chr5:140700576 TAF7 -0.61 -5.14 -0.42 1.04e-6 Pulmonary function decline; TGCT cis rs6663390 0.510 rs6540445 chr1:208081467 A/G cg03990033 chr1:208084030 CD34 -0.7 -6.08 -0.48 1.36e-8 Facial morphology (factor 18); TGCT cis rs8013055 0.796 rs4075104 chr14:106000214 C/A cg23356831 chr14:105996513 TMEM121 0.34 5.31 0.43 4.91e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs2760061 0.598 rs1774755 chr1:228115282 T/G cg18477163 chr1:228402036 OBSCN -0.31 -6.27 -0.49 5.55e-9 Diastolic blood pressure; TGCT cis rs2708977 0.965 rs12717781 chr2:97249142 G/A cg01950434 chr2:97203154 ARID5A 0.64 5.84 0.46 4.38e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs666930 0.519 rs477992 chr1:120257576 A/G cg19096424 chr1:120255104 PHGDH 0.64 5.88 0.47 3.62e-8 Breast cancer; TGCT trans rs6740731 0.518 rs35766785 chr2:145295628 C/T cg19463199 chr3:197401858 MIR922;KIAA0226 0.38 6.77 0.52 4.64e-10 Coronary artery disease; TGCT trans rs1974653 0.672 rs9606231 chr22:20065276 T/C cg08822737 chr17:71088851 SLC39A11 -0.9 -7.22 -0.54 4.57e-11 Schizophrenia; TGCT cis rs2629540 0.765 rs12221075 chr10:126534855 G/A cg08799069 chr10:126477246 METTL10 -0.28 -4.58 -0.38 1.12e-5 Cocaine dependence; TGCT cis rs4808199 1.000 rs17288409 chr19:19504167 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.7 5.07 0.41 1.41e-6 Nonalcoholic fatty liver disease; TGCT cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs10782582 0.609 rs10873797 chr1:76377191 G/T cg03433033 chr1:76189801 ACADM -0.5 -4.88 -0.4 3.15e-6 Daytime sleep phenotypes; TGCT cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs4455778 0.501 rs10250970 chr7:49052491 T/C cg26309511 chr7:48887640 NA 0.51 6.67 0.51 7.54e-10 Lung cancer in never smokers; TGCT cis rs968567 0.559 rs174544 chr11:61567753 C/A cg01500311 chr11:61656094 FADS3 -0.32 -5.34 -0.43 4.25e-7 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs2153535 0.580 rs7767756 chr6:8453428 A/C cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs13326165 0.760 rs1077142 chr3:52403526 A/G cg07884673 chr3:53033167 SFMBT1 0.4 4.86 0.4 3.45e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs11208691 0.513 rs72480644 chr1:66159417 C/G cg14976592 chr1:65886160 LEPROT;LEPR 0.63 4.85 0.4 3.63e-6 Lymphocyte percentage of white cells; TGCT cis rs2688608 0.592 rs11000758 chr10:75493610 A/T cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs7103648 0.695 rs11039290 chr11:47572279 G/A cg20307385 chr11:47447363 PSMC3 0.88 8.56 0.61 3.56e-14 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs4268898 0.697 rs10445892 chr2:24406958 T/C cg05570707 chr2:24270316 C2orf44 0.49 4.84 0.4 3.73e-6 Asthma; TGCT cis rs611744 0.967 rs655707 chr8:109197530 T/C cg21045802 chr8:109455806 TTC35 0.5 4.5 0.37 1.53e-5 Dupuytren's disease; TGCT cis rs13202913 0.837 rs9397054 chr6:151789912 C/T cg03627880 chr6:151815985 C6orf97 -0.76 -5.84 -0.46 4.24e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7267979 0.899 rs442834 chr20:25458096 A/G cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg17345569 chr6:42928274 GNMT -0.47 -4.81 -0.4 4.25e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2050392 0.799 rs2907 chr10:30728250 A/G cg18806716 chr10:30721971 MAP3K8 -0.51 -6.0 -0.47 2.05e-8 Inflammatory bowel disease; TGCT cis rs7267979 0.932 rs367666 chr20:25449818 T/C cg14121845 chr20:25566513 NINL 0.5 5.42 0.44 3.01e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6426558 0.537 rs488104 chr1:227300277 G/A cg10327440 chr1:227177885 CDC42BPA 0.58 6.91 0.53 2.21e-10 Neutrophil percentage of white cells; TGCT trans rs561341 0.609 rs2051810 chr17:30195841 C/T cg20587970 chr11:113659929 NA 0.67 8.22 0.59 2.35e-13 Hip circumference adjusted for BMI; TGCT cis rs7147624 0.572 rs2411813 chr14:66023906 G/A cg03016385 chr14:66212404 NA -0.49 -6.56 -0.51 1.32e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs10089 0.953 rs72794400 chr5:127516028 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.06 0.59 5.58e-13 Ileal carcinoids; TGCT cis rs4654899 0.785 rs7531381 chr1:21403348 A/G cg01072550 chr1:21505969 NA -0.56 -9.15 -0.63 1.42e-15 Superior frontal gyrus grey matter volume; TGCT cis rs7503807 0.967 rs4889867 chr17:78593058 C/T cg06872548 chr17:78716983 RPTOR 0.25 4.56 0.38 1.2e-5 Obesity; TGCT cis rs769267 0.965 rs8103496 chr19:19386015 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs4689388 0.926 rs4343789 chr4:6285228 C/G cg00701064 chr4:6280414 WFS1 0.46 6.31 0.49 4.55e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs11644362 0.966 rs12933348 chr16:12991081 C/T cg06890432 chr16:12997467 SHISA9 -0.61 -6.87 -0.52 2.78e-10 Positive affect;Subjective well-being; TGCT cis rs10744422 0.858 rs4759389 chr12:123308615 A/G cg25930673 chr12:123319894 HIP1R -0.85 -4.97 -0.41 2.13e-6 Schizophrenia; TGCT cis rs7209700 0.547 rs10514919 chr17:45342129 G/T cg21624342 chr17:45890973 OSBPL7 0.19 4.77 0.39 5.02e-6 IgG glycosylation; TGCT cis rs4478858 0.735 rs4949393 chr1:31851875 G/A cg00250761 chr1:31883323 NA -0.25 -4.46 -0.37 1.83e-5 Alcohol dependence; TGCT cis rs35883536 0.647 rs2783702 chr1:101040836 G/A cg06223162 chr1:101003688 GPR88 0.42 8.0 0.58 7.5e-13 Monocyte count; TGCT cis rs8180040 0.966 rs3816779 chr3:47543389 C/T cg27129171 chr3:47204927 SETD2 0.64 7.68 0.57 4.17e-12 Colorectal cancer; TGCT cis rs3796352 1.000 rs3796352 chr3:52913279 C/T cg15956490 chr3:53032818 SFMBT1 0.56 4.94 0.41 2.52e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3099143 0.908 rs3102716 chr15:77051003 T/G cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Recalcitrant atopic dermatitis; TGCT cis rs1050631 1.000 rs1050631 chr18:33694120 A/G cg25426722 chr18:33708991 SLC39A6;ELP2 -0.49 -4.86 -0.4 3.43e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs916888 0.610 rs199452 chr17:44801340 C/T cg15921436 chr17:44337874 NA 0.41 6.25 0.49 5.98e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11190604 0.767 rs11190519 chr10:102175133 C/T cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7178572 0.688 rs12591335 chr15:77774894 A/G cg22256960 chr15:77711686 NA 0.83 6.95 0.53 1.88e-10 Type 2 diabetes; TGCT cis rs28595532 0.920 rs116108618 chr4:119763585 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs3008870 1.000 rs2985811 chr1:67377722 G/T cg03991309 chr1:68237761 GNG12 0.27 4.68 0.39 7.28e-6 Lymphocyte percentage of white cells; TGCT cis rs7777754 0.734 rs4947709 chr7:50672907 A/G cg18232548 chr7:50535776 DDC -0.31 -4.96 -0.41 2.29e-6 Response to zileuton treatment in asthma (FEV1 change interaction); TGCT cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1008375 0.966 rs3733576 chr4:17586703 T/C cg18681998 chr4:17616180 MED28 0.85 8.18 0.59 2.86e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg13683864 chr3:40499215 RPL14 1.01 10.44 0.68 1.1e-18 Renal cell carcinoma; TGCT cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs62380364 0.602 rs665324 chr5:88055517 T/C cg22951263 chr5:87985283 NA -0.59 -6.32 -0.49 4.3e-9 Intelligence (multi-trait analysis); TGCT cis rs4919044 0.866 rs835265 chr10:94786259 A/G cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs853679 0.585 rs201004 chr6:27804934 T/C cg10876282 chr6:28092338 ZSCAN16 0.58 4.79 0.39 4.76e-6 Depression; TGCT cis rs4711350 0.953 rs942496 chr6:33788055 A/G cg18005901 chr6:33739558 LEMD2 -0.59 -6.08 -0.48 1.36e-8 Schizophrenia; TGCT cis rs2236918 0.710 rs1776138 chr1:242027075 G/A cg04158730 chr1:242011433 EXO1 0.56 5.36 0.43 3.88e-7 Menopause (age at onset); TGCT cis rs8077577 0.945 rs34474249 chr17:18074525 T/C cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs9611565 0.649 rs5751144 chr22:42128097 A/G cg13695892 chr22:41940480 POLR3H -0.83 -8.18 -0.59 2.79e-13 Vitiligo; TGCT cis rs75059851 0.756 rs7127156 chr11:133839857 T/C cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs7017914 0.967 rs12680166 chr8:71678638 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs9467773 0.935 rs9461270 chr6:26544110 A/G cg15659132 chr6:26577336 NA 0.86 12.17 0.74 6.67e-23 Intelligence (multi-trait analysis); TGCT cis rs4689388 0.890 rs6838400 chr4:6295427 C/G cg25554036 chr4:6271136 WFS1 0.53 7.33 0.55 2.58e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs17376456 0.569 rs6879620 chr5:93119893 G/A cg25358565 chr5:93447407 FAM172A -0.76 -6.68 -0.51 7.23e-10 Diabetic retinopathy; TGCT cis rs854765 0.718 rs6502629 chr17:17869642 A/G cg09796270 chr17:17721594 SREBF1 0.26 5.13 0.42 1.09e-6 Total body bone mineral density; TGCT cis rs9527 0.637 rs12219247 chr10:104613361 A/G cg04362960 chr10:104952993 NT5C2 0.55 4.74 0.39 5.7e-6 Arsenic metabolism; TGCT cis rs3749237 0.595 rs1464566 chr3:49459376 T/C cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs7523050 0.730 rs41279678 chr1:109440215 G/A cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs7208859 0.673 rs9913782 chr17:29237384 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7760949 0.889 rs9475806 chr6:13934527 A/G cg27413430 chr6:13925136 RNF182 0.73 6.79 0.52 4.22e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs35146811 0.735 rs1727130 chr7:99811464 C/G cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs2688608 0.592 rs11814282 chr10:75490217 T/C cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs2243480 1.000 rs10807702 chr7:65767843 C/T cg07424592 chr7:64974309 NA 1.35 7.47 0.56 1.27e-11 Diabetic kidney disease; TGCT cis rs35306767 0.903 rs12761424 chr10:967295 C/T cg20503657 chr10:835505 NA 0.65 9.44 0.65 2.93e-16 Eosinophil percentage of granulocytes; TGCT cis rs10782582 0.609 rs79835994 chr1:76287508 G/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs1372520 0.684 rs2619356 chr4:90750844 C/T cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs6089829 0.890 rs6062775 chr20:61663650 T/C cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7809950 0.817 rs4727678 chr7:107083635 C/G cg23024343 chr7:107201750 COG5 -0.48 -7.05 -0.54 1.08e-10 Coronary artery disease; TGCT cis rs72781680 0.898 rs56179550 chr2:23934867 C/T cg08917208 chr2:24149416 ATAD2B 0.89 5.41 0.44 3.11e-7 Lymphocyte counts; TGCT cis rs11167764 0.945 rs7720832 chr5:141473097 T/G cg08523384 chr5:141488047 NDFIP1 -0.24 -4.91 -0.4 2.85e-6 Crohn's disease; TGCT cis rs2692947 0.567 rs4907276 chr2:96391109 G/T cg00336220 chr2:96940284 SNRNP200 -0.16 -4.44 -0.37 1.96e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs500492 0.542 rs2744148 chr16:1073552 A/G cg01366354 chr16:1075121 NA 0.34 5.02 0.41 1.77e-6 Polycystic ovary syndrome; TGCT cis rs7267979 0.966 rs2500433 chr20:25296335 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1061377 1.000 rs7676008 chr4:39121774 G/C cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs4689388 0.890 rs4342257 chr4:6290037 G/C cg25554036 chr4:6271136 WFS1 0.54 7.54 0.56 8.85e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6964587 1.000 rs10234434 chr7:91673308 A/T cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs7937682 0.889 rs551825 chr11:111480116 C/G cg09085632 chr11:111637200 PPP2R1B -1.05 -11.39 -0.72 5.21e-21 Primary sclerosing cholangitis; TGCT cis rs7666738 0.830 rs13139078 chr4:99020774 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg11965913 chr1:205819406 PM20D1 0.63 9.98 0.67 1.38e-17 Menarche (age at onset); TGCT cis rs7726839 0.574 rs72705014 chr5:619815 C/G cg20362242 chr5:692897 TPPP 0.52 4.48 0.37 1.68e-5 Obesity-related traits; TGCT cis rs10791097 0.694 rs4459316 chr11:130756176 T/C cg05962950 chr11:130786565 SNX19 0.9 11.06 0.7 3.32e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg07424592 chr7:64974309 NA 0.54 5.29 0.43 5.44e-7 Calcium levels; TGCT cis rs9942416 0.601 rs40059 chr5:74964582 A/G cg02573091 chr5:74908125 NA -0.39 -4.56 -0.38 1.22e-5 Age-related disease endophenotypes; TGCT cis rs9457247 1.000 rs376551 chr6:167384923 G/A cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs1577917 0.958 rs4707229 chr6:86546237 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs9911578 1.000 rs8071916 chr17:56660279 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.28 -0.49 5.09e-9 Intelligence (multi-trait analysis); TGCT cis rs12580194 0.593 rs55637917 chr12:55747565 T/C cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs2204008 0.749 rs4579984 chr12:38166266 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.68 0.57 4.21e-12 Bladder cancer; TGCT cis rs17030434 0.682 rs1339 chr4:154631563 T/C cg14289246 chr4:154710475 SFRP2 -0.73 -5.39 -0.44 3.41e-7 Electrocardiographic conduction measures; TGCT cis rs4746818 0.793 rs2008553 chr10:70860475 C/G cg11621586 chr10:70884670 VPS26A 1.07 8.98 0.63 3.62e-15 Left atrial antero-posterior diameter; TGCT cis rs7674212 0.570 rs6813563 chr4:104099110 G/A cg16532752 chr4:104119610 CENPE -0.59 -5.37 -0.43 3.76e-7 Type 2 diabetes; TGCT cis rs7772486 0.875 rs9390371 chr6:146363180 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.784 rs4795361 chr17:37573446 G/A cg07936489 chr17:37558343 FBXL20 -0.65 -4.98 -0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs9381040 0.655 rs7775972 chr6:41038116 A/C cg03526776 chr6:41159608 TREML2 0.27 5.37 0.43 3.78e-7 Alzheimer's disease (late onset); TGCT cis rs1348850 0.626 rs1901825 chr2:178225331 A/T cg22681709 chr2:178499509 PDE11A -0.35 -4.54 -0.38 1.3e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs6920364 1 rs6920364 chr6:167376466 G/C cg23791538 chr6:167370224 RNASET2 0.53 5.19 0.42 8.41e-7 Lung cancer; TGCT cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs11098499 0.691 rs9995716 chr4:120264996 T/C cg09307838 chr4:120376055 NA 0.55 5.41 0.44 3.16e-7 Corneal astigmatism; TGCT cis rs1150668 0.796 rs1124132 chr6:28380321 T/G cg13525197 chr6:28411240 ZSCAN23 -0.51 -5.0 -0.41 1.93e-6 Pubertal anthropometrics; TGCT cis rs6964587 1.000 rs2282971 chr7:91584356 A/G cg17063962 chr7:91808500 NA 0.85 9.43 0.65 2.97e-16 Breast cancer; TGCT cis rs12291225 0.585 rs10832242 chr11:14340504 C/T cg19336497 chr11:14380999 RRAS2 0.45 7.25 0.55 3.87e-11 Sense of smell; TGCT cis rs10465746 0.780 rs11163872 chr1:84421969 G/T cg10977910 chr1:84465055 TTLL7 0.66 6.73 0.52 5.71e-10 Obesity-related traits; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg23131131 chr22:24373011 LOC391322 0.57 4.52 0.38 1.41e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT trans rs11722228 0.522 rs7681250 chr4:10133013 G/T cg26043149 chr18:55253948 FECH 1.23 14.06 0.78 1.97e-27 Gout;Urate levels;Serum uric acid levels; TGCT cis rs941408 0.515 rs7253128 chr19:2776982 C/T cg26465405 chr19:3039745 TLE2 -0.22 -4.52 -0.38 1.44e-5 Total cholesterol levels; TGCT cis rs7772486 0.790 rs6917135 chr6:146152426 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.72 0.39 6.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs739401 0.611 rs3782069 chr11:3033275 G/A cg25174290 chr11:3078921 CARS 0.49 4.81 0.4 4.28e-6 Longevity; TGCT cis rs10779751 0.770 rs2486922 chr1:11124885 T/C cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs7726839 0.540 rs3792720 chr5:643028 T/G cg16624210 chr5:671434 TPPP 0.4 4.52 0.38 1.44e-5 Obesity-related traits; TGCT cis rs10927875 0.722 rs945425 chr1:16348412 T/C cg21385522 chr1:16154831 NA 0.62 6.41 0.5 2.76e-9 Dilated cardiomyopathy; TGCT cis rs11249608 0.636 rs6888567 chr5:178449074 C/T cg21905437 chr5:178450457 ZNF879 -0.46 -4.63 -0.38 9.21e-6 Pubertal anthropometrics; TGCT cis rs68170813 0.559 rs17427849 chr7:106864237 A/G cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.43e-8 Coronary artery disease; TGCT cis rs5750830 0.649 rs5757657 chr22:39798429 G/T cg11247378 chr22:39784982 NA -0.74 -10.33 -0.68 1.98e-18 Intelligence (multi-trait analysis); TGCT cis rs950169 0.922 rs62029585 chr15:84951874 C/G cg12863693 chr15:85201151 NMB 0.45 4.7 0.39 6.73e-6 Schizophrenia; TGCT cis rs9926296 0.535 rs36022917 chr16:89893238 A/G cg04287289 chr16:89883240 FANCA 0.67 6.82 0.52 3.63e-10 Vitiligo; TGCT cis rs9926296 0.508 rs1558184 chr16:89842374 T/G cg21285383 chr16:89894308 SPIRE2 0.46 7.23 0.54 4.35e-11 Vitiligo; TGCT cis rs7474896 0.515 rs688608 chr10:38331624 G/A cg25427524 chr10:38739819 LOC399744 0.34 4.52 0.38 1.4e-5 Obesity (extreme); TGCT trans rs4824093 0.610 rs73443923 chr22:50285348 C/T cg09872104 chr7:134855509 C7orf49 -1.07 -8.89 -0.62 5.98e-15 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2010099 0.759 rs116358073 chr3:124299095 G/A cg04915618 chr3:124304960 KALRN 0.52 4.73 0.39 6.01e-6 Thyroid peroxidase antibody levels; TGCT cis rs858239 0.600 rs9691762 chr7:23125922 G/C cg05602783 chr7:23145260 KLHL7 -0.64 -5.4 -0.44 3.21e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2956278 0.717 rs2956286 chr12:84689964 T/C cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs7727544 0.716 rs3844312 chr5:131582356 C/T cg24060327 chr5:131705240 SLC22A5 -0.56 -5.5 -0.44 2.06e-7 Blood metabolite levels; TGCT cis rs3820928 1.000 rs3820928 chr2:227773466 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.78 -0.39 4.77e-6 Pulmonary function; TGCT cis rs1903068 0.853 rs10012701 chr4:56002776 A/G cg09978860 chr4:56023921 NA 0.56 6.34 0.49 3.88e-9 Endometriosis; TGCT cis rs72945132 0.678 rs35733235 chr11:70235595 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.17 0.54 5.79e-11 Coronary artery disease; TGCT cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 7.77 0.57 2.61e-12 Platelet count; TGCT trans rs4332037 0.707 rs56070303 chr7:1891015 C/T cg25206134 chr2:45395956 NA 0.96 8.1 0.59 4.34e-13 Bipolar disorder; TGCT cis rs2274273 0.522 rs2251366 chr14:55518156 A/G cg01923255 chr14:55878535 KIAA0831 0.56 4.76 0.39 5.24e-6 Protein biomarker; TGCT cis rs838147 0.537 rs485073 chr19:49207255 A/G cg13540341 chr19:49222985 MAMSTR -0.37 -4.79 -0.4 4.69e-6 Dietary macronutrient intake; TGCT cis rs477895 1.000 rs477895 chr11:64048912 C/T cg04317338 chr11:64019027 PLCB3 -0.73 -5.88 -0.47 3.49e-8 Mean platelet volume; TGCT cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg03517284 chr6:25882590 NA 0.51 5.32 0.43 4.74e-7 Blood metabolite levels; TGCT cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs2836974 0.644 rs2836986 chr21:40702136 A/C cg17971929 chr21:40555470 PSMG1 -0.68 -5.96 -0.47 2.47e-8 Cognitive function; TGCT cis rs2816062 0.786 rs2816055 chr1:18898248 A/G cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg08280861 chr8:58055591 NA 0.54 6.0 0.47 2.05e-8 Developmental language disorder (linguistic errors); TGCT cis rs10782582 0.609 rs5745543 chr1:76365111 A/T cg10523679 chr1:76189770 ACADM -0.58 -5.31 -0.43 4.92e-7 Daytime sleep phenotypes; TGCT cis rs9926296 0.605 rs886952 chr16:89836781 G/A cg21285383 chr16:89894308 SPIRE2 0.44 6.97 0.53 1.69e-10 Vitiligo; TGCT cis rs6964587 0.967 rs9656003 chr7:91766322 A/C cg22709100 chr7:91322751 NA 0.28 4.44 0.37 1.96e-5 Breast cancer; TGCT cis rs9467773 0.506 rs9393709 chr6:26365147 C/T cg05738196 chr6:26577821 NA -0.63 -6.61 -0.51 1.01e-9 Intelligence (multi-trait analysis); TGCT cis rs11711311 0.955 rs11715350 chr3:113418376 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -6.69 -0.52 6.78e-10 IgG glycosylation; TGCT cis rs10782582 0.593 rs11589276 chr1:76105545 G/A cg10523679 chr1:76189770 ACADM -0.68 -7.45 -0.56 1.4e-11 Daytime sleep phenotypes; TGCT cis rs797680 0.786 rs10874772 chr1:93787770 G/A cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11190604 1.000 rs2295773 chr10:102265815 A/G cg16342193 chr10:102329863 NA -0.38 -4.89 -0.4 3.06e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6424115 1.000 rs6697805 chr1:24151996 C/A cg15997130 chr1:24165203 NA -0.92 -10.57 -0.69 5.26e-19 Immature fraction of reticulocytes; TGCT cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg06634786 chr22:41940651 POLR3H -0.86 -8.32 -0.6 1.34e-13 Vitiligo; TGCT cis rs7582180 0.663 rs2309800 chr2:100992086 C/T cg14675211 chr2:100938903 LONRF2 0.46 4.44 0.37 1.97e-5 Intelligence (multi-trait analysis); TGCT cis rs478304 0.651 rs10896037 chr11:65503424 A/G cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.05e-10 Acne (severe); TGCT trans rs10953454 1.000 rs35324592 chr7:104480715 A/G cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs1857353 1.000 rs60194830 chr1:75888706 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs11792861 0.591 rs10979613 chr9:111687584 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.66 7.51 0.56 1.01e-11 Menarche (age at onset); TGCT cis rs9303401 0.659 rs34878689 chr17:56694330 G/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg24829409 chr8:58192753 C8orf71 -0.55 -5.2 -0.42 8.06e-7 Developmental language disorder (linguistic errors); TGCT cis rs9527 0.569 rs78193706 chr10:104780564 T/C cg15744005 chr10:104629667 AS3MT -0.42 -4.92 -0.4 2.74e-6 Arsenic metabolism; TGCT cis rs11043280 0.703 rs11043275 chr12:122402723 T/C cg22618164 chr12:122356400 WDR66 0.6 5.71 0.46 7.75e-8 Mean platelet volume; TGCT cis rs7819412 0.775 rs6601564 chr8:10982051 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.62 -0.38 9.44e-6 Triglycerides; TGCT cis rs72627509 0.723 rs67043033 chr4:57739233 A/G cg26694713 chr4:57773883 REST 0.81 6.35 0.5 3.7e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs4654899 0.680 rs4233274 chr1:21121678 C/T cg01072550 chr1:21505969 NA -0.53 -8.53 -0.61 4.4e-14 Superior frontal gyrus grey matter volume; TGCT cis rs67311347 0.506 rs55962832 chr3:40244451 T/C cg13683864 chr3:40499215 RPL14 -0.79 -7.4 -0.55 1.83e-11 Renal cell carcinoma; TGCT cis rs10779751 0.632 rs2748876 chr1:11134157 T/G cg08854313 chr1:11322531 MTOR 0.85 6.96 0.53 1.74e-10 Body mass index; TGCT cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg13665807 chr20:60559372 TAF4 -0.51 -5.28 -0.43 5.63e-7 Body mass index; TGCT cis rs7772486 0.875 rs12194437 chr6:146411440 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7590720 0.819 rs1344694 chr2:216893637 T/G cg12620499 chr2:216877984 MREG 0.91 10.87 0.7 9.89e-20 Alcohol dependence; TGCT cis rs600231 0.706 rs3782091 chr11:65336483 G/T cg13974409 chr11:65292307 SCYL1 -0.45 -4.53 -0.38 1.35e-5 Bone mineral density; TGCT cis rs9913156 0.789 rs55999196 chr17:4600655 A/G cg23387401 chr17:4582204 PELP1 0.31 4.68 0.39 7.44e-6 Lymphocyte counts; TGCT cis rs7572733 0.555 rs1837495 chr2:198921201 A/G cg00792783 chr2:198669748 PLCL1 -0.56 -4.83 -0.4 3.97e-6 Dermatomyositis; TGCT cis rs4319547 0.774 rs7307233 chr12:123124301 C/G cg23029597 chr12:123009494 RSRC2 -0.27 -4.73 -0.39 6.11e-6 Body mass index; TGCT cis rs2933343 0.649 rs789214 chr3:128594995 A/G cg11901034 chr3:128598214 ACAD9 -0.65 -6.04 -0.48 1.65e-8 IgG glycosylation; TGCT cis rs17401966 0.540 rs4846216 chr1:10447792 A/T cg19773385 chr1:10388646 KIF1B 0.22 5.27 0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs6921919 0.525 rs16894095 chr6:28390230 C/T cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.29 -0.43 5.35e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs492146 0.935 rs316128 chr6:52849146 G/T cg06706454 chr6:52930286 FBXO9 -0.47 -4.54 -0.38 1.29e-5 Epilepsy (remission after treatment); TGCT cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1395 0.813 rs11685326 chr2:27453679 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.47 0.65 2.4e-16 Blood metabolite levels; TGCT cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs13256369 1.000 rs885000 chr8:8568875 G/T cg18904891 chr8:8559673 CLDN23 0.59 5.54 0.45 1.73e-7 Obesity-related traits; TGCT cis rs4654899 0.865 rs7532667 chr1:21438239 A/G cg01072550 chr1:21505969 NA -0.47 -7.02 -0.53 1.27e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6681544 0.760 rs3790895 chr1:82401515 T/C cg04226724 chr1:82268649 LPHN2 0.48 4.97 0.41 2.19e-6 Metabolite levels (X-11787); TGCT cis rs920590 0.527 rs79929516 chr8:19650050 G/C cg03894339 chr8:19674705 INTS10 0.82 5.29 0.43 5.28e-7 Acute lymphoblastic leukemia (childhood); TGCT cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.98 10.7 0.69 2.47e-19 Intelligence (multi-trait analysis); TGCT cis rs4788570 0.624 rs9929985 chr16:71838458 A/G cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs9788682 0.747 rs6495308 chr15:78907656 A/G cg24631222 chr15:78858424 CHRNA5 0.78 5.84 0.46 4.22e-8 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs40363 0.645 rs1690450 chr16:3521051 G/A cg22508957 chr16:3507546 NAT15 0.48 5.42 0.44 3.04e-7 Tuberculosis; TGCT cis rs763121 0.819 rs5750658 chr22:39060917 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.9e-12 Menopause (age at onset); TGCT cis rs4665809 1.000 rs11126375 chr2:26344787 G/A cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs9910055 0.530 rs11656758 chr17:42301541 A/G cg19774624 chr17:42201019 HDAC5 -0.7 -7.46 -0.56 1.29e-11 Total body bone mineral density; TGCT cis rs2230307 0.536 rs687513 chr1:100598867 C/T cg24955406 chr1:100503596 HIAT1 -0.74 -5.03 -0.41 1.68e-6 Carotid intima media thickness; TGCT cis rs9527 0.590 rs7901197 chr10:104840433 C/T cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs8031584 0.752 rs7174744 chr15:31183747 G/A cg08109568 chr15:31115862 NA 0.33 4.45 0.37 1.89e-5 Huntington's disease progression; TGCT cis rs11190604 0.767 rs11190534 chr10:102190930 G/A cg16342193 chr10:102329863 NA -0.38 -5.0 -0.41 1.93e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3774830 0.846 rs11731730 chr4:5454545 C/T cg26943120 chr4:5472116 STK32B 0.21 4.68 0.39 7.48e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.542 rs630858 chr2:219409689 C/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs9467773 1.000 rs11756120 chr6:26529808 G/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.846 rs446031 chr6:145885592 C/T cg23711669 chr6:146136114 FBXO30 0.85 9.23 0.64 9.21e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs3806843 0.576 rs155361 chr5:140307284 G/A cg07102913 chr5:140593443 PCDHB13 -0.46 -4.6 -0.38 1.01e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7017914 0.967 rs6993115 chr8:71699183 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs9916302 0.706 rs4795385 chr17:37733148 A/G cg03321784 chr17:37729644 NA -0.44 -4.58 -0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs9790314 0.740 rs4856767 chr3:161004379 C/T cg03342759 chr3:160939853 NMD3 -0.5 -5.53 -0.44 1.79e-7 Morning vs. evening chronotype; TGCT cis rs861020 0.606 rs2184919 chr1:210000015 C/T cg05527609 chr1:210001259 C1orf107 -0.88 -8.37 -0.6 1.05e-13 Orofacial clefts; TGCT cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.1 14.26 0.79 6.49e-28 Height; TGCT cis rs10193935 0.892 rs12622152 chr2:42482929 C/A cg27598129 chr2:42591480 NA -0.39 -5.41 -0.44 3.06e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6964587 1.000 rs2282972 chr7:91666369 C/T cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs2832191 0.903 rs11700687 chr21:30486767 A/G cg24692254 chr21:30365293 RNF160 -0.83 -8.71 -0.62 1.58e-14 Dental caries; TGCT cis rs10791323 0.628 rs10750543 chr11:133718467 G/A cg15485101 chr11:133734466 NA 0.42 5.28 0.43 5.54e-7 Childhood ear infection; TGCT cis rs9303401 0.614 rs3803753 chr17:56540110 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.77 0.52 4.6e-10 Cognitive test performance; TGCT cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg13395646 chr4:1353034 KIAA1530 -0.48 -6.12 -0.48 1.16e-8 Obesity-related traits; TGCT cis rs7010267 0.935 rs10955915 chr8:119963547 A/G cg17171407 chr8:119960777 TNFRSF11B 0.33 6.18 0.49 8.29e-9 Total body bone mineral density (age 45-60); TGCT cis rs13191362 0.810 rs28360533 chr6:162996742 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2050392 0.792 rs9338188 chr10:30721963 G/C cg18806716 chr10:30721971 MAP3K8 -0.48 -5.53 -0.44 1.85e-7 Inflammatory bowel disease; TGCT cis rs10089 0.953 rs10463839 chr5:127519675 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 7.83 0.58 1.83e-12 Ileal carcinoids; TGCT cis rs8070740 0.617 rs1058119 chr17:5323125 C/A cg25236894 chr17:5323110 RPAIN;NUP88 0.64 6.3 0.49 4.68e-9 Menopause (age at onset); TGCT cis rs7542091 0.704 rs7550330 chr1:210044587 G/A cg22029157 chr1:209979665 IRF6 0.64 6.1 0.48 1.23e-8 Monobrow; TGCT cis rs3820068 0.580 rs36100011 chr1:16046920 C/T cg05660106 chr1:15850417 CASP9 0.73 6.75 0.52 5.18e-10 Systolic blood pressure; TGCT cis rs3947 0.738 rs1293328 chr8:11695060 C/T cg02840367 chr8:11660030 FDFT1 0.89 6.56 0.51 1.3e-9 Blood protein levels; TGCT cis rs3809566 0.654 rs6494384 chr15:63325607 C/G cg08198488 chr15:63333792 TPM1 -0.35 -5.25 -0.43 6.5e-7 Platelet count; TGCT cis rs7926906 1.000 rs7926906 chr11:90524290 C/A cg26138821 chr11:89956704 CHORDC1 -0.51 -5.52 -0.44 1.92e-7 Intelligence (multi-trait analysis); TGCT cis rs4886920 0.518 rs12902224 chr15:78076272 T/C cg25212270 chr15:78015279 NA -0.29 -5.17 -0.42 8.99e-7 Neuroticism; TGCT cis rs2836974 0.644 rs11088472 chr21:40699376 A/C cg11890956 chr21:40555474 PSMG1 -0.72 -6.44 -0.5 2.33e-9 Cognitive function; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg04234412 chr22:24373322 LOC391322 -0.91 -10.67 -0.69 2.98e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs250677 0.522 rs10038913 chr5:148354224 A/G cg18129178 chr5:148520854 ABLIM3 0.36 4.62 0.38 9.43e-6 Breast cancer; TGCT cis rs8077577 0.895 rs1563371 chr17:18111793 C/T cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg04546413 chr19:29218101 NA 0.83 6.68 0.51 7.35e-10 Methadone dose in opioid dependence; TGCT cis rs78487399 0.808 rs7581586 chr2:43668176 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11031096 0.542 rs10835337 chr11:3958828 A/G cg08557956 chr11:4115526 RRM1 0.49 4.44 0.37 1.97e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs42648 0.905 rs42641 chr7:89972764 T/C cg25739043 chr7:89950458 NA -0.77 -7.82 -0.57 1.96e-12 Homocysteine levels; TGCT cis rs9549367 0.713 rs3024761 chr13:113824090 C/G cg00898013 chr13:113819073 PROZ 0.52 6.5 0.5 1.75e-9 Platelet distribution width; TGCT cis rs60843830 1.000 rs3791224 chr2:221981 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.75 6.86 0.52 2.9e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs3849570 0.643 rs1969433 chr3:81968869 T/C cg07356753 chr3:81810745 GBE1 -0.64 -5.62 -0.45 1.19e-7 Waist circumference;Body mass index; TGCT cis rs7909074 0.899 rs2026428 chr10:45389452 T/C cg05187965 chr10:45406764 TMEM72 -0.25 -5.31 -0.43 4.96e-7 Mean corpuscular volume; TGCT cis rs6088580 0.624 rs6120645 chr20:33025171 C/T cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs1371867 0.846 rs2439458 chr8:101297984 T/C cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg17554472 chr22:41940697 POLR3H 0.51 5.52 0.44 1.9e-7 Vitiligo; TGCT cis rs35934224 0.783 rs5993849 chr22:19866194 G/C cg11182965 chr22:19864308 TXNRD2 -0.38 -5.4 -0.44 3.27e-7 Glaucoma (primary open-angle); TGCT cis rs1691799 0.899 rs1168308 chr12:66742183 A/G cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs2084898 0.891 rs2511023 chr11:120009145 A/G cg00437969 chr11:120009135 TRIM29 0.34 4.47 0.37 1.77e-5 Stroke (pediatric); TGCT cis rs2836974 0.897 rs1571709 chr21:40553980 T/C cg06238570 chr21:40685208 BRWD1 0.75 7.06 0.54 1.07e-10 Cognitive function; TGCT cis rs7681440 0.874 rs1372522 chr4:90765280 A/G cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs367615 0.679 rs10070786 chr5:108815081 T/G cg17395555 chr5:108820864 NA 0.31 5.85 0.47 4.07e-8 Colorectal cancer (SNP x SNP interaction); TGCT trans rs2257129 1.000 rs7904102 chr10:122916891 C/G cg11273493 chr8:10928985 XKR6 -0.81 -7.69 -0.57 3.88e-12 Coronary artery disease;Body mass index; TGCT cis rs769267 0.930 rs2099334 chr19:19578450 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.73 0.46 7.3e-8 Tonsillectomy; TGCT cis rs425277 0.583 rs1467217 chr1:2045165 G/A cg24578937 chr1:2090814 PRKCZ -0.23 -5.42 -0.44 3e-7 Height; TGCT trans rs629535 0.734 rs542288 chr8:70057149 G/T cg21567404 chr3:27674614 NA -0.56 -8.82 -0.62 8.75e-15 Dupuytren's disease; TGCT cis rs9473924 0.542 rs66834257 chr6:50809141 G/A cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs9581857 0.685 rs79699519 chr13:28023241 C/T cg22138327 chr13:27999177 GTF3A 0.7 5.01 0.41 1.85e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7439150 0.954 rs2227399 chr4:155485853 T/G cg22130008 chr4:155548532 NA -0.48 -5.93 -0.47 2.8e-8 Fibrinogen levels; TGCT cis rs4889855 0.530 rs11654265 chr17:78602697 G/A cg16591659 chr17:78472290 NA 0.28 4.45 0.37 1.89e-5 Fractional excretion of uric acid; TGCT cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.61 -0.51 9.98e-10 Alzheimer's disease; TGCT trans rs9388451 0.903 rs7758115 chr6:126061502 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.26 -0.6 1.87e-13 Brugada syndrome; TGCT cis rs875971 1.000 rs4717300 chr7:65947380 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs4786125 0.581 rs7193000 chr16:6918270 G/C cg03623568 chr16:6915990 A2BP1 -0.44 -6.57 -0.51 1.27e-9 Heart rate variability traits (SDNN); TGCT cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs68170813 0.652 rs17481621 chr7:107113852 G/C cg02696742 chr7:106810147 HBP1 -0.65 -4.93 -0.4 2.55e-6 Coronary artery disease; TGCT cis rs9341808 0.667 rs2490239 chr6:80826289 G/A cg08355045 chr6:80787529 NA 0.32 5.31 0.43 4.88e-7 Sitting height ratio; TGCT cis rs1322512 0.959 rs2758798 chr6:152943980 A/G cg03415253 chr6:152958462 SYNE1 -0.57 -4.98 -0.41 2.05e-6 Tonometry; TGCT cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg00149659 chr3:10157352 C3orf10 0.97 5.98 0.47 2.19e-8 Alzheimer's disease; TGCT cis rs55910451 0.723 rs3736461 chr10:5855403 G/C cg09234995 chr10:5726438 C10orf18 0.49 4.65 0.39 8.26e-6 Breast cancer; TGCT cis rs9399135 0.935 rs9376086 chr6:135371329 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs3796352 0.686 rs1560333 chr3:53138254 T/C cg07884673 chr3:53033167 SFMBT1 -0.51 -5.82 -0.46 4.73e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1878931 0.501 rs9635547 chr16:3416664 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.12 0.54 7.61e-11 Body mass index (adult); TGCT cis rs2479724 0.870 rs6902650 chr6:41764080 G/A cg08135965 chr6:41755394 TOMM6 -0.49 -4.82 -0.4 4.06e-6 Menarche (age at onset); TGCT cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs2463822 0.925 rs1528730 chr11:62081181 A/C cg06239285 chr11:62104954 ASRGL1 0.92 6.16 0.48 9.2e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2439831 0.867 rs45585139 chr15:43700427 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.05 6.66 0.51 8.08e-10 Lung cancer in ever smokers; TGCT cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg06238570 chr21:40685208 BRWD1 0.69 6.39 0.5 3.07e-9 Cognitive function; TGCT cis rs5769765 1.000 rs2092982 chr22:50282204 C/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.81 0.73 5.03e-22 Schizophrenia; TGCT cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg08439880 chr3:133502540 NA -0.29 -5.42 -0.44 2.93e-7 Iron status biomarkers; TGCT trans rs1005277 0.557 rs2983338 chr10:38550734 C/T cg17830980 chr10:43048298 ZNF37B -0.82 -10.29 -0.68 2.47e-18 Extrinsic epigenetic age acceleration; TGCT cis rs4699052 0.626 rs10017383 chr4:104249957 G/A cg16532752 chr4:104119610 CENPE -0.49 -4.89 -0.4 3.07e-6 Testicular germ cell tumor; TGCT cis rs7829975 0.560 rs17154599 chr8:8551418 C/T cg15556689 chr8:8085844 FLJ10661 -0.54 -4.72 -0.39 6.39e-6 Mood instability; TGCT cis rs7937682 0.961 rs7119563 chr11:111543916 T/A cg09085632 chr11:111637200 PPP2R1B 1.04 9.57 0.65 1.36e-16 Primary sclerosing cholangitis; TGCT cis rs7666738 0.830 rs1813972 chr4:98886828 C/A cg18180107 chr4:99064573 C4orf37 0.53 4.84 0.4 3.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs904251 0.772 rs1224127 chr6:37417556 G/A cg25019722 chr6:37503610 NA -0.46 -5.32 -0.43 4.71e-7 Cognitive performance; TGCT cis rs244731 0.959 rs7724098 chr5:176659570 G/A cg06060754 chr5:176797920 RGS14 -0.45 -6.34 -0.49 3.93e-9 Urate levels in lean individuals; TGCT cis rs9430161 0.644 rs6685766 chr1:11037051 T/C cg02454025 chr1:11042201 C1orf127 0.92 11.24 0.71 1.21e-20 Ewing sarcoma; TGCT cis rs7954584 0.583 rs6486782 chr12:122359172 T/C cg13699009 chr12:122356056 WDR66 0.32 7.33 0.55 2.6e-11 Mean corpuscular volume; TGCT cis rs9393777 0.513 rs1104871 chr6:26665235 T/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.61 -4.95 -0.41 2.33e-6 Intelligence (multi-trait analysis); TGCT cis rs7523050 0.643 rs34801874 chr1:109404382 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs9303401 0.614 rs12947982 chr17:57140301 A/G cg25039879 chr17:56429692 SUPT4H1 0.54 4.84 0.4 3.85e-6 Cognitive test performance; TGCT cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs10186029 0.676 rs1025820 chr2:213933778 T/G cg08319019 chr2:214017104 IKZF2 0.63 5.94 0.47 2.67e-8 Systemic sclerosis; TGCT cis rs921968 0.541 rs687747 chr2:219399627 T/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs3824662 0.592 rs9746 chr10:8116503 A/G cg20314737 chr10:8096579 FLJ45983;GATA3 0.66 4.61 0.38 9.73e-6 Acute lymphoblastic leukemia (B-cell precursor);Acute lymphoblastic leukemia (adolescents and young adults); TGCT cis rs7662987 0.517 rs2602882 chr4:100040765 C/T cg12011299 chr4:100065546 ADH4 0.4 4.77 0.39 5.18e-6 Smoking initiation; TGCT cis rs34734847 1.000 rs3021338 chr12:121162989 A/G cg21892295 chr12:121157589 UNC119B -0.23 -5.59 -0.45 1.4e-7 Mean corpuscular volume; TGCT trans rs4824093 0.610 rs56810176 chr22:50303149 G/C cg09872104 chr7:134855509 C7orf49 -0.93 -6.91 -0.53 2.29e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs3806843 1.000 rs3756340 chr5:140180451 T/G cg19875535 chr5:140030758 IK 0.36 6.11 0.48 1.21e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7523050 0.730 rs72984628 chr1:109460808 G/A cg08274380 chr1:109419600 GPSM2 1.27 6.86 0.52 2.9e-10 Fat distribution (HIV); TGCT cis rs11098499 0.644 rs10009566 chr4:120558608 A/G cg09307838 chr4:120376055 NA 0.66 6.09 0.48 1.31e-8 Corneal astigmatism; TGCT cis rs10504229 1.000 rs72650887 chr8:58177343 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs208520 0.909 rs9354411 chr6:67019930 A/G cg07460842 chr6:66804631 NA 0.73 5.91 0.47 3.07e-8 Exhaled nitric oxide output; TGCT cis rs3771570 0.579 rs62190373 chr2:242388685 G/A cg21155796 chr2:242212141 HDLBP 0.93 6.65 0.51 8.25e-10 Prostate cancer; TGCT cis rs7666738 0.830 rs1349757 chr4:99058763 C/G cg05340658 chr4:99064831 C4orf37 0.52 5.92 0.47 2.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13242816 1.000 rs2191498 chr7:116138569 C/T cg02799643 chr7:116139180 CAV2 -0.45 -5.85 -0.47 4.03e-8 P wave duration; TGCT cis rs9733 0.596 rs11204704 chr1:150671630 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.81 0.4 4.38e-6 Tonsillectomy; TGCT cis rs9381040 0.655 rs2294696 chr6:41036988 A/G cg03526776 chr6:41159608 TREML2 -0.27 -5.28 -0.43 5.66e-7 Alzheimer's disease (late onset); TGCT cis rs2239547 0.603 rs6805298 chr3:53096552 A/G cg11645453 chr3:52864694 ITIH4 -0.29 -4.59 -0.38 1.08e-5 Schizophrenia; TGCT cis rs6701037 0.681 rs6664840 chr1:175128726 A/G cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT cis rs881375 0.678 rs2269060 chr9:123683569 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.52 5.86 0.47 3.95e-8 Rheumatoid arthritis; TGCT cis rs1371867 0.775 rs6511 chr8:101252680 T/C cg00191853 chr8:101177733 SPAG1 0.24 4.83 0.4 3.87e-6 Atrioventricular conduction; TGCT cis rs4713118 0.669 rs200997 chr6:27811815 G/A cg10876282 chr6:28092338 ZSCAN16 0.5 4.78 0.39 4.84e-6 Parkinson's disease; TGCT cis rs7267979 0.966 rs2263204 chr20:25377688 A/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs151997 0.962 rs27844 chr5:50190680 T/G cg06027927 chr5:50259733 NA 0.47 4.83 0.4 4e-6 Callous-unemotional behaviour; TGCT cis rs12791968 1.000 rs12791968 chr11:45001490 C/T cg11846598 chr11:44996168 LOC221122 0.34 6.74 0.52 5.25e-10 Inhibitory control; TGCT cis rs7949030 0.688 rs11231155 chr11:62365619 A/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.52 0.65 1.88e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2657888 0.628 rs2638285 chr12:56886361 A/G cg23002907 chr12:56915593 RBMS2 0.4 5.26 0.43 6.06e-7 Adiponectin levels; TGCT cis rs727563 0.593 rs5758461 chr22:42162189 G/C cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs35146811 0.735 rs1727139 chr7:99815367 C/T cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs2463822 0.925 rs17157227 chr11:62169772 A/G cg06239285 chr11:62104954 ASRGL1 0.75 4.91 0.4 2.8e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs742614 0.935 rs6057930 chr20:32477972 C/T cg03217337 chr20:32447030 NA -0.22 -4.64 -0.38 8.88e-6 Stearic acid (18:0) levels; TGCT cis rs3784262 0.715 rs1994927 chr15:58347949 C/A cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.34 -0.49 3.96e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7119 0.717 rs12910513 chr15:77817258 C/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs4975709 0.610 rs4975706 chr5:1860365 G/T cg07747251 chr5:1868357 NA 0.38 5.43 0.44 2.84e-7 Cardiovascular disease risk factors; TGCT cis rs10882165 0.636 rs12357018 chr10:94903515 C/T cg15980076 chr10:94822747 CYP26C1 -0.43 -4.83 -0.4 3.94e-6 Refractive error; TGCT cis rs4730250 0.707 rs3729877 chr7:106787065 T/G cg02696742 chr7:106810147 HBP1 0.73 5.99 0.47 2.09e-8 Osteoarthritis; TGCT cis rs10504229 1.000 rs68114352 chr8:58196081 C/T cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs8017423 0.935 rs11159959 chr14:90733656 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -7.36 -0.55 2.2e-11 Mortality in heart failure; TGCT cis rs1865760 0.566 rs2858993 chr6:26087856 T/A cg16482183 chr6:26056742 HIST1H1C 0.57 4.79 0.39 4.76e-6 Height; TGCT cis rs317689 0.718 rs160827 chr12:69770147 G/A cg14784868 chr12:69753453 YEATS4 0.55 4.68 0.39 7.24e-6 Response to diuretic therapy; TGCT cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg09904177 chr6:26538194 HMGN4 0.61 5.89 0.47 3.42e-8 Intelligence (multi-trait analysis); TGCT cis rs4517514 0.509 rs11018870 chr11:89871409 T/G cg05041596 chr11:89867385 NAALAD2 0.53 4.7 0.39 6.89e-6 Trans fatty acid levels; TGCT cis rs6598955 0.627 rs7550127 chr1:26592871 C/T cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs3749237 1.000 rs4768 chr3:49758764 A/G cg07636037 chr3:49044803 WDR6 0.65 5.75 0.46 6.7e-8 Resting heart rate; TGCT cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 -0.93 -7.4 -0.55 1.79e-11 Platelet count; TGCT cis rs4253772 0.832 rs6008259 chr22:46633782 G/A cg09491104 chr22:46646882 C22orf40 -0.49 -4.77 -0.39 5.1e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs6964587 0.755 rs13229505 chr7:91444679 G/T cg17063962 chr7:91808500 NA 0.82 8.31 0.6 1.43e-13 Breast cancer; TGCT cis rs611744 0.604 rs6469170 chr8:109305277 T/C cg21045802 chr8:109455806 TTC35 0.75 7.99 0.58 8.06e-13 Dupuytren's disease; TGCT cis rs7772486 0.738 rs2246334 chr6:146183635 G/A cg13319975 chr6:146136371 FBXO30 -0.52 -4.64 -0.38 8.61e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 1.000 rs115915387 chr4:119640854 C/T cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT cis rs2115630 0.645 rs3825878 chr15:85174755 C/T cg17173187 chr15:85201210 NMB -0.48 -5.78 -0.46 5.69e-8 P wave terminal force; TGCT cis rs2239785 0.959 rs136163 chr22:36657628 T/G cg15716373 chr22:36655542 APOL1 -0.43 -4.92 -0.4 2.64e-6 Glomerulosclerosis; TGCT cis rs11578119 0.836 rs12130105 chr1:170357956 T/A cg09767346 chr1:170501363 GORAB 0.61 4.58 0.38 1.1e-5 Male-pattern baldness; TGCT cis rs7666738 0.830 rs13119995 chr4:99026790 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6545883 0.965 rs1992765 chr2:61751333 A/G cg15711740 chr2:61764176 XPO1 -0.57 -5.31 -0.43 4.99e-7 Tuberculosis; TGCT cis rs7216064 0.817 rs28609796 chr17:65855104 T/A cg12091567 chr17:66097778 LOC651250 -0.84 -6.56 -0.51 1.29e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1865760 0.865 rs9467650 chr6:25958235 A/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs7027203 1.000 rs7864114 chr9:96551954 A/G cg14396892 chr9:96623032 NA 0.24 4.81 0.4 4.27e-6 DNA methylation (variation); TGCT cis rs1971762 0.583 rs3852561 chr12:54085842 C/T cg16917193 chr12:54089295 NA 1.38 18.38 0.86 3.23e-37 Height; TGCT cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg07061783 chr6:25882402 NA -0.5 -5.47 -0.44 2.33e-7 Blood metabolite levels; TGCT cis rs7772486 0.790 rs4075694 chr6:146251108 G/C cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs8014204 0.762 rs12889665 chr14:75234830 T/G cg06637938 chr14:75390232 RPS6KL1 0.58 5.13 0.42 1.11e-6 Caffeine consumption; TGCT cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg12311346 chr5:56204834 C5orf35 -0.65 -6.44 -0.5 2.37e-9 Initial pursuit acceleration; TGCT cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg23205692 chr1:25664452 TMEM50A -0.53 -5.67 -0.45 9.31e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs317689 0.690 rs10878946 chr12:69642315 C/T cg11871910 chr12:69753446 YEATS4 0.53 4.47 0.37 1.77e-5 Response to diuretic therapy; TGCT cis rs231513 0.822 rs231520 chr17:41956983 T/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs4824093 0.535 rs73443931 chr22:50291603 G/A cg20569369 chr22:51173646 NA 0.28 4.58 0.38 1.13e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs4455778 0.519 rs6583488 chr7:49039939 A/G cg26309511 chr7:48887640 NA 0.51 6.66 0.51 7.85e-10 Lung cancer in never smokers; TGCT cis rs7726839 0.540 rs7558 chr5:660491 C/T cg16624210 chr5:671434 TPPP 0.41 4.54 0.38 1.31e-5 Obesity-related traits; TGCT cis rs854765 0.693 rs8079418 chr17:17924060 C/T cg09796270 chr17:17721594 SREBF1 0.26 5.19 0.42 8.52e-7 Total body bone mineral density; TGCT cis rs317689 0.718 rs160827 chr12:69770147 G/A cg20891283 chr12:69753455 YEATS4 0.56 4.71 0.39 6.52e-6 Response to diuretic therapy; TGCT trans rs4650994 1.000 rs4650999 chr1:178532188 A/C cg05059571 chr16:84539110 KIAA1609 0.41 7.7 0.57 3.78e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg20637647 chr7:64974828 NA 0.92 5.38 0.44 3.53e-7 Diabetic kidney disease; TGCT cis rs1371867 0.846 rs1660353 chr8:101250907 C/T cg06636551 chr8:101224915 SPAG1 0.44 6.11 0.48 1.19e-8 Atrioventricular conduction; TGCT cis rs7677751 0.848 rs7673625 chr4:55088586 C/T cg17187183 chr4:55093834 PDGFRA 0.53 6.87 0.52 2.83e-10 Corneal astigmatism; TGCT cis rs2153535 0.580 rs2327053 chr6:8443127 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs769267 0.930 rs4808208 chr19:19650096 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.66 5.42 0.44 3.01e-7 Tonsillectomy; TGCT cis rs7617480 0.648 rs6796790 chr3:48780317 G/A cg07636037 chr3:49044803 WDR6 0.76 6.36 0.5 3.6e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs17767294 0.614 rs72854506 chr6:28252497 T/C cg08851530 chr6:28072375 NA 1.54 6.89 0.53 2.51e-10 Parkinson's disease; TGCT cis rs4819052 0.851 rs10470245 chr21:46658912 A/G cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2204008 0.728 rs12369538 chr12:38443942 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.59 0.56 6.74e-12 Bladder cancer; TGCT cis rs12142240 0.698 rs17357621 chr1:46807697 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT trans rs10506458 0.915 rs17763441 chr12:63418335 T/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.48 -0.56 1.18e-11 Hemostatic factors and hematological phenotypes; TGCT cis rs904251 0.504 rs1757188 chr6:37483808 A/G cg01843034 chr6:37503916 NA -0.54 -7.33 -0.55 2.57e-11 Cognitive performance; TGCT cis rs4988958 0.565 rs3771154 chr2:103039360 C/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg14893161 chr1:205819251 PM20D1 0.66 10.84 0.7 1.13e-19 Menarche (age at onset); TGCT cis rs9291683 0.554 rs7668175 chr4:10125782 T/C cg11266682 chr4:10021025 SLC2A9 -0.45 -5.32 -0.43 4.65e-7 Bone mineral density; TGCT cis rs1008375 1.000 rs4698635 chr4:17630242 C/A cg16339924 chr4:17578868 LAP3 0.62 5.11 0.42 1.17e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11252926 0.599 rs11252213 chr10:454694 C/T cg18196295 chr10:418757 DIP2C 0.28 4.45 0.37 1.92e-5 Psychosis in Alzheimer's disease; TGCT cis rs6089829 0.962 rs6062778 chr20:61663959 A/G cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs916888 0.610 rs199530 chr17:44836653 C/T cg17911788 chr17:44343683 NA 0.45 5.4 0.44 3.3e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs208515 0.518 rs12209790 chr6:66662965 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.87 9.38 0.64 4.06e-16 Exhaled nitric oxide levels; TGCT cis rs28595532 0.920 rs17324821 chr4:119770716 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg03806693 chr22:41940476 POLR3H -1.07 -11.33 -0.71 7.31e-21 Vitiligo; TGCT cis rs2836974 0.897 rs68090597 chr21:40535633 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.51 0.65 1.92e-16 Cognitive function; TGCT cis rs1801251 1.000 rs895430 chr2:233725483 C/A cg25237894 chr2:233734115 C2orf82 -0.31 -5.52 -0.44 1.89e-7 Coronary artery disease; TGCT cis rs6121246 0.529 rs6058196 chr20:30194714 A/T cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs7552404 0.924 rs1146580 chr1:76209935 T/C cg10523679 chr1:76189770 ACADM 0.84 9.32 0.64 5.67e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7100689 0.646 rs10749579 chr10:82140959 C/T cg01528321 chr10:82214614 TSPAN14 0.81 8.21 0.59 2.4e-13 Post bronchodilator FEV1; TGCT cis rs7772486 0.754 rs697053 chr6:145989807 T/C cg23711669 chr6:146136114 FBXO30 -0.93 -10.56 -0.69 5.5e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs7312933 0.558 rs11181466 chr12:42765181 A/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.14 0.42 1.03e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs13242816 1.000 rs34228114 chr7:116106986 C/T cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs2243480 1.000 rs160652 chr7:65538431 A/G cg20637647 chr7:64974828 NA 0.95 5.8 0.46 5.3e-8 Diabetic kidney disease; TGCT cis rs9357506 1.000 rs12055411 chr6:46306565 A/C cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg11141652 chr22:24348549 GSTTP1 0.34 4.76 0.39 5.37e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs308447 0.516 rs13127908 chr4:123720933 G/C cg10495464 chr4:123653540 BBS12;LOC729338 0.63 5.77 0.46 5.98e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs9611565 0.592 rs8779 chr22:42070276 T/C cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Vitiligo; TGCT cis rs6671200 0.607 rs3753872 chr1:95699184 T/G cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs13191362 0.935 rs34063386 chr6:163041271 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.92 7.24 0.55 4.11e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs523522 0.962 rs603574 chr12:120998443 A/G cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs9303401 0.659 rs35828828 chr17:56718205 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.69 6.6 0.51 1.07e-9 Cognitive test performance; TGCT cis rs6988636 0.710 rs17316158 chr8:124157607 A/C cg27053337 chr8:124217698 FAM83A 0.67 5.12 0.42 1.11e-6 Urinary uromodulin levels; TGCT trans rs629535 0.773 rs489206 chr8:70064883 T/C cg21567404 chr3:27674614 NA 0.56 8.82 0.62 8.75e-15 Dupuytren's disease; TGCT cis rs9611565 0.506 rs2024566 chr22:41697338 A/G cg06634786 chr22:41940651 POLR3H -0.63 -5.66 -0.45 1.01e-7 Vitiligo; TGCT cis rs17767294 0.708 rs72848766 chr6:27908756 T/C cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs6540559 0.673 rs2357230 chr1:210019498 G/A cg23283495 chr1:209979779 IRF6 0.6 4.5 0.37 1.54e-5 Cleft lip with or without cleft palate; TGCT cis rs9911578 1.000 rs654778 chr17:56736473 A/C cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.806 rs7375599 chr4:9954918 C/T cg11266682 chr4:10021025 SLC2A9 0.63 8.61 0.61 2.71e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg00149659 chr3:10157352 C3orf10 0.84 5.52 0.44 1.86e-7 Alzheimer's disease; TGCT cis rs1577917 1.000 rs12190604 chr6:86716215 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs11098499 0.697 rs11941899 chr4:120382758 C/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs28595532 0.841 rs115852209 chr4:119753465 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7681440 0.904 rs7698219 chr4:90771351 C/A cg14346243 chr4:90757452 SNCA -0.57 -5.5 -0.44 2.04e-7 Dementia with Lewy bodies; TGCT cis rs9443645 0.901 rs1572584 chr6:79690290 A/G cg05283184 chr6:79620031 NA 0.2 4.44 0.37 1.96e-5 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs137699 0.959 rs5757633 chr22:39756270 A/G cg24399712 chr22:39784796 NA -0.63 -5.54 -0.45 1.73e-7 IgG glycosylation; TGCT cis rs7829975 0.606 rs6601274 chr8:8799059 T/G cg06636001 chr8:8085503 FLJ10661 -0.79 -6.94 -0.53 1.96e-10 Mood instability; TGCT cis rs2836974 0.799 rs13047550 chr21:40515495 T/C cg17971929 chr21:40555470 PSMG1 0.95 8.67 0.61 2.01e-14 Cognitive function; TGCT cis rs6542838 0.671 rs6752025 chr2:99505699 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.55 -5.2 -0.42 7.88e-7 Fear of minor pain; TGCT cis rs12145833 0.596 rs3926866 chr1:243437632 G/C cg02356786 chr1:243265016 LOC731275 0.65 4.49 0.37 1.59e-5 Obesity (early onset extreme); TGCT cis rs2742234 0.955 rs2503841 chr10:43675721 C/T cg02780029 chr10:43622663 RET -0.26 -4.97 -0.41 2.19e-6 Hirschsprung disease; TGCT cis rs12142240 0.692 rs7529674 chr1:46818508 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs13217239 0.621 rs12527231 chr6:27001288 G/A cg05738196 chr6:26577821 NA 0.49 4.75 0.39 5.45e-6 Schizophrenia; TGCT cis rs9921222 0.565 rs10903014 chr16:377623 A/G cg12437481 chr16:420112 MRPL28 -0.48 -4.63 -0.38 9.17e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs35306767 0.903 rs12761424 chr10:967295 C/T cg26597838 chr10:835615 NA 0.63 9.0 0.63 3.31e-15 Eosinophil percentage of granulocytes; TGCT cis rs709400 0.663 rs62007687 chr14:103903763 G/T cg12935359 chr14:103987150 CKB -0.36 -5.47 -0.44 2.42e-7 Body mass index; TGCT cis rs2439831 1.000 rs689647 chr15:43762196 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs9653442 0.564 rs11123809 chr2:100758137 C/T cg07810366 chr2:100720526 AFF3 -0.35 -5.09 -0.42 1.31e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7208859 0.524 rs73263982 chr17:28920624 T/C cg04154034 chr17:28927549 LRRC37B2 0.79 4.8 0.4 4.54e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12477438 0.871 rs62156364 chr2:99695097 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -6.64 -0.51 8.63e-10 Chronic sinus infection; TGCT cis rs262150 0.579 rs4909110 chr7:158787332 C/T cg01219135 chr7:158766336 NA -0.46 -4.82 -0.4 4.09e-6 Facial morphology (factor 20); TGCT cis rs35883536 0.647 rs17411209 chr1:101046734 A/G cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs7226408 0.857 rs72890514 chr18:34588028 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2153535 0.541 rs5026687 chr6:8473957 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.7 0.46 8.28e-8 Motion sickness; TGCT cis rs9303401 0.659 rs34818467 chr17:56643109 C/T cg10487724 chr17:56770010 TEX14;RAD51C -0.65 -6.22 -0.49 7.12e-9 Cognitive test performance; TGCT cis rs10540 1.000 rs78520676 chr11:517173 G/A cg03934478 chr11:495069 RNH1 0.32 4.82 0.4 4.16e-6 Body mass index; TGCT cis rs7296418 0.699 rs1109559 chr12:123757861 C/T cg00376283 chr12:123451042 ABCB9 0.66 5.89 0.47 3.37e-8 Platelet count; TGCT cis rs10465746 0.935 rs6692233 chr1:84327214 A/G cg10977910 chr1:84465055 TTLL7 -0.64 -6.24 -0.49 6.39e-9 Obesity-related traits; TGCT cis rs10876993 0.855 rs1689601 chr12:58049557 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg05215272 chr17:6899095 ALOX12 0.56 6.71 0.52 6.18e-10 Tonsillectomy; TGCT cis rs6964587 1.000 rs13239875 chr7:91716104 G/A cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs200895692 1 rs200895692 chr1:43421956 CGCCTGTAATCCCAG/C cg09824328 chr1:43425412 SLC2A1 -0.57 -4.9 -0.4 2.91e-6 Monocyte count; TGCT cis rs589249 0.963 rs218985 chr1:37169665 A/G cg04012535 chr1:37176647 NA 0.33 5.5 0.44 2.07e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs12048904 0.505 rs11166508 chr1:101233511 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.81 -6.96 -0.53 1.78e-10 Multiple sclerosis; TGCT trans rs8073060 0.614 rs72829932 chr17:34055935 A/G cg19694781 chr19:47549865 TMEM160 0.6 12.13 0.74 8.13e-23 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs4654899 0.865 rs61779120 chr1:21481230 T/C cg01072550 chr1:21505969 NA -0.48 -7.21 -0.54 4.91e-11 Superior frontal gyrus grey matter volume; TGCT trans rs1005277 0.579 rs2749612 chr10:38488610 G/A cg27523141 chr10:43048294 ZNF37B 0.73 8.51 0.61 4.68e-14 Extrinsic epigenetic age acceleration; TGCT cis rs6570726 0.902 rs373321 chr6:145854150 T/A cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.790 rs2265917 chr6:146212285 A/G cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.89e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.565 rs958075 chr20:25595123 C/T cg03522245 chr20:25566470 NINL -0.45 -4.66 -0.39 8.06e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2075371 0.966 rs1619682 chr7:133996703 T/G cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs9902453 0.933 rs7225462 chr17:28321226 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.61 0.56 5.93e-12 Coffee consumption (cups per day); TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs9972944 0.902 rs9972883 chr17:63771316 C/A cg07283582 chr17:63770753 CCDC46 0.28 5.89 0.47 3.34e-8 Total body bone mineral density; TGCT cis rs933688 1.000 rs2059207 chr5:90731931 C/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.07 10.69 0.69 2.68e-19 Smoking behavior; TGCT cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs6951245 0.744 rs10265758 chr7:1172518 C/T cg18402987 chr7:1209562 NA 0.63 6.04 0.48 1.67e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2180341 1.000 rs6904520 chr6:127629802 T/C cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs11098499 0.955 rs56386062 chr4:120155135 T/C cg24670566 chr4:120433619 PDE5A 0.22 4.44 0.37 1.96e-5 Corneal astigmatism; TGCT cis rs6964587 1.000 rs7785095 chr7:91640773 A/T cg17063962 chr7:91808500 NA -0.83 -8.66 -0.61 2.14e-14 Breast cancer; TGCT cis rs4455778 0.580 rs4541847 chr7:49109824 C/G cg26309511 chr7:48887640 NA -0.49 -6.17 -0.48 9.08e-9 Lung cancer in never smokers; TGCT cis rs4788570 0.615 rs1423983 chr16:71701248 G/A cg06353428 chr16:71660113 MARVELD3 1.56 12.54 0.75 8.54e-24 Intelligence (multi-trait analysis); TGCT cis rs425277 0.606 rs424079 chr1:2071340 C/A cg03732007 chr1:2071316 PRKCZ -0.27 -6.37 -0.5 3.37e-9 Height; TGCT cis rs8141529 0.748 rs1318025 chr22:29283757 C/T cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs73001065 0.818 rs73004966 chr19:19716558 C/T cg03709012 chr19:19516395 GATAD2A 1.04 5.1 0.42 1.26e-6 LDL cholesterol; TGCT cis rs1163251 0.902 rs511059 chr1:120217081 G/T cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs10782582 0.593 rs77733234 chr1:76101655 A/T cg22875332 chr1:76189707 ACADM -0.52 -6.26 -0.49 5.72e-9 Daytime sleep phenotypes; TGCT cis rs2204008 0.683 rs7305703 chr12:38138381 T/C cg13010199 chr12:38710504 ALG10B 0.6 4.8 0.4 4.57e-6 Bladder cancer; TGCT cis rs6920965 0.503 rs2475851 chr6:126174215 T/C cg05901451 chr6:126070800 HEY2 -0.58 -5.12 -0.42 1.12e-6 High light scatter reticulocyte count; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.76 -7.13 -0.54 7.43e-11 Prudent dietary pattern; TGCT cis rs7681440 0.845 rs6843084 chr4:90766230 T/C cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs7224685 0.530 rs36019144 chr17:3987499 T/C cg09580393 chr17:4869866 SPAG7 -0.39 -4.5 -0.37 1.53e-5 Type 2 diabetes; TGCT cis rs377070 0.873 rs309399 chr4:123614839 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.46 5.08 0.42 1.35e-6 Mosquito bite size; TGCT cis rs1005277 0.505 rs13503 chr10:38239843 C/A cg25427524 chr10:38739819 LOC399744 0.38 7.67 0.57 4.25e-12 Extrinsic epigenetic age acceleration; TGCT cis rs4654899 1.000 rs6426660 chr1:21361640 A/G cg01072550 chr1:21505969 NA -0.49 -7.87 -0.58 1.47e-12 Superior frontal gyrus grey matter volume; TGCT cis rs6598955 0.670 rs4659366 chr1:26542572 G/A cg01614726 chr1:26633154 UBXN11 0.49 4.67 0.39 7.59e-6 Obesity-related traits; TGCT cis rs8038465 0.624 rs2127015 chr15:73985223 T/C cg15420318 chr15:73925796 NPTN 0.59 5.62 0.45 1.21e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28595532 0.920 rs115797971 chr4:119779620 A/G cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs2204008 0.627 rs10878486 chr12:38148601 T/G cg26384229 chr12:38710491 ALG10B 0.85 7.47 0.56 1.27e-11 Bladder cancer; TGCT cis rs17108533 0.588 rs12886230 chr14:71301207 A/T cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs7312933 0.558 rs11181507 chr12:42844763 T/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 5.02 0.41 1.73e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs35934224 0.891 rs33997573 chr22:19868951 C/T cg11182965 chr22:19864308 TXNRD2 -0.36 -5.11 -0.42 1.21e-6 Glaucoma (primary open-angle); TGCT cis rs739496 0.527 rs12319165 chr12:112340734 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9911578 1.000 rs9902994 chr17:56948722 T/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT trans rs2727020 0.930 rs1164688 chr11:49290604 C/G cg03929089 chr4:120376271 NA 0.71 7.73 0.57 3.16e-12 Coronary artery disease; TGCT cis rs5769707 0.967 rs2051626 chr22:50008973 G/A cg20744362 chr22:50050164 C22orf34 0.29 4.74 0.39 5.83e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg13695892 chr22:41940480 POLR3H 0.9 8.87 0.62 6.78e-15 Vitiligo; TGCT cis rs9549260 0.755 rs1923249 chr13:41143881 C/A cg21288729 chr13:41239152 FOXO1 0.98 10.08 0.67 8.21e-18 Red blood cell count; TGCT cis rs2439831 0.717 rs9806227 chr15:43680115 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.88 6.11 0.48 1.19e-8 Lung cancer in ever smokers; TGCT cis rs2639990 1.000 rs609303 chr18:72895242 C/T cg18449964 chr18:72917101 ZADH2 0.91 6.22 0.49 7e-9 Vascular endothelial growth factor levels; TGCT cis rs12497850 0.931 rs4974079 chr3:48906469 T/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs11779988 0.545 rs10095395 chr8:17750589 T/A cg01800426 chr8:17659068 MTUS1 -0.57 -5.13 -0.42 1.09e-6 Breast cancer; TGCT trans rs931812 0.895 rs4734016 chr8:101910071 C/T cg20993868 chr7:22813445 NA 0.4 8.97 0.63 3.87e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs1371867 0.846 rs1788189 chr8:101249762 G/T cg06002616 chr8:101225028 SPAG1 0.54 6.4 0.5 2.87e-9 Atrioventricular conduction; TGCT cis rs1887596 0.672 rs1854815 chr13:27173485 A/C cg01312412 chr13:27282625 NA 0.31 5.56 0.45 1.61e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs9611565 0.559 rs132765 chr22:42008068 A/G cg06481639 chr22:41940642 POLR3H 0.74 6.64 0.51 8.88e-10 Vitiligo; TGCT trans rs7618501 0.633 rs4688689 chr3:50035542 C/T cg21659725 chr3:3221576 CRBN 0.72 8.69 0.62 1.81e-14 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7829975 0.846 rs1879957 chr8:8544808 T/C cg06636001 chr8:8085503 FLJ10661 -0.6 -5.0 -0.41 1.92e-6 Mood instability; TGCT cis rs7937682 0.961 rs491937 chr11:111494947 A/T cg09085632 chr11:111637200 PPP2R1B -1.0 -9.76 -0.66 4.88e-17 Primary sclerosing cholangitis; TGCT cis rs9549367 0.789 rs3794422 chr13:113893729 G/A cg18105134 chr13:113819100 PROZ -0.34 -5.49 -0.44 2.14e-7 Platelet distribution width; TGCT cis rs916888 0.773 rs199533 chr17:44828931 G/A cg01570182 chr17:44337453 NA 1.07 9.72 0.66 6.04e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs13191362 1.000 rs35449999 chr6:163023465 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7772486 0.790 rs2247206 chr6:146216184 C/T cg23711669 chr6:146136114 FBXO30 0.87 9.97 0.67 1.48e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs55881798 chr8:58106406 T/C cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs2538470 0.869 rs2538475 chr7:148213611 T/C cg20325032 chr7:149129312 ZNF777 0.24 4.63 0.38 8.98e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs8067545 0.750 rs4267380 chr17:19971564 A/G cg13482628 chr17:19912719 NA 0.51 4.43 0.37 2.01e-5 Schizophrenia; TGCT cis rs12135062 0.851 rs2651927 chr1:3101762 A/C cg21609526 chr1:3105151 PRDM16 -0.4 -6.44 -0.5 2.41e-9 Migraine; TGCT cis rs5751150 1 rs5751150 chr22:42153292 T/G cg06634786 chr22:41940651 POLR3H 0.86 8.01 0.58 7.16e-13 Cannabis dependence symptom count; TGCT cis rs6088580 0.634 rs6058052 chr20:33047084 A/G cg06115741 chr20:33292138 TP53INP2 0.54 4.71 0.39 6.47e-6 Glomerular filtration rate (creatinine); TGCT cis rs9650657 0.504 rs2409724 chr8:11041642 A/T cg21775007 chr8:11205619 TDH -0.49 -4.55 -0.38 1.25e-5 Neuroticism; TGCT cis rs6988636 1.000 rs13260798 chr8:124190192 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs61990749 0.544 rs176962 chr14:78185510 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs12497850 0.931 rs9755490 chr3:48871664 A/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs2067615 0.542 rs11113120 chr12:107203460 T/C cg15890332 chr12:107067104 RFX4 0.28 5.57 0.45 1.52e-7 Heart rate; TGCT trans rs1814175 0.646 rs1722010 chr11:49897958 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.58 -0.69 4.9e-19 Height; TGCT cis rs4566357 0.615 rs4350744 chr2:227918146 A/T cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs4663866 0.901 rs35390666 chr2:239193578 C/T cg17283117 chr2:239148619 HES6 1.01 4.66 0.39 8.09e-6 Irritable bowel syndrome; TGCT cis rs9942416 0.660 rs66493518 chr5:74990125 G/C cg19683494 chr5:74908142 NA 0.59 6.26 0.49 5.62e-9 Age-related disease endophenotypes; TGCT cis rs12048904 0.647 rs7528268 chr1:101329295 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.89 8.36 0.6 1.06e-13 Multiple sclerosis; TGCT cis rs28830936 0.510 rs7175346 chr15:42100674 G/A cg17847044 chr15:42102381 MAPKBP1 -0.19 -5.23 -0.43 7e-7 Diastolic blood pressure; TGCT cis rs7824557 0.836 rs765731 chr8:11121498 T/A cg21775007 chr8:11205619 TDH -0.6 -5.88 -0.47 3.63e-8 Retinal vascular caliber; TGCT cis rs116095464 0.558 rs13354585 chr5:242263 G/C cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs12765878 1.000 rs4918067 chr10:105644636 A/C cg11005552 chr10:105648138 OBFC1 0.45 7.89 0.58 1.36e-12 Coronary artery disease; TGCT cis rs12510870 0.599 rs10020054 chr4:74448638 G/A cg05868023 chr4:75230803 EREG -0.54 -4.71 -0.39 6.6e-6 Iris color (b* coordinate); TGCT cis rs1018836 0.851 rs12548741 chr8:91628878 G/A cg16814680 chr8:91681699 NA -0.86 -9.19 -0.64 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6089829 0.925 rs2277767 chr20:61666937 G/A cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs911555 0.519 rs8014069 chr14:104004311 A/C cg12935359 chr14:103987150 CKB -0.35 -4.54 -0.38 1.3e-5 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs7599781 chr2:43678726 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4455778 0.580 rs6974104 chr7:49126777 C/G cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Vitiligo; TGCT cis rs28595532 0.920 rs17325192 chr4:119780345 A/G cg21997857 chr4:120227080 C4orf3 -0.46 -4.55 -0.38 1.25e-5 Cannabis dependence symptom count; TGCT cis rs10992471 0.580 rs12341093 chr9:95234182 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.79 -0.46 5.39e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4665809 0.877 rs35224700 chr2:26298037 T/C cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 3e-8 Gut microbiome composition (summer); TGCT cis rs13108904 0.539 rs11247997 chr4:1361057 T/C cg03303774 chr4:1407052 NA 0.35 5.52 0.44 1.94e-7 Obesity-related traits; TGCT cis rs3820928 0.648 rs1997484 chr2:227898962 T/A cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs7523273 0.606 rs1970530 chr1:207924066 G/A cg22525895 chr1:207977042 MIR29B2 0.51 8.18 0.59 2.87e-13 Schizophrenia; TGCT cis rs9914988 0.943 rs9907178 chr17:27124307 G/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7617773 0.743 rs4632568 chr3:48367819 C/T cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs4699052 0.963 rs11733615 chr4:104157164 C/T cg16532752 chr4:104119610 CENPE -0.56 -5.27 -0.43 5.78e-7 Testicular germ cell tumor; TGCT cis rs6840360 0.571 rs62327277 chr4:152555905 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT trans rs8073060 0.544 rs225252 chr17:33952401 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.3 -0.77 1.24e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs616402 0.527 rs589151 chr1:10567711 C/T cg17425144 chr1:10567563 PEX14 0.57 8.21 0.59 2.43e-13 Breast size; TGCT cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg13695892 chr22:41940480 POLR3H -0.87 -8.24 -0.59 2.06e-13 Vitiligo; TGCT cis rs3617 0.539 rs11922975 chr3:52936763 C/T cg10802521 chr3:52805072 NEK4 0.58 6.45 0.5 2.27e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg13397359 chr6:42928475 GNMT 0.69 6.1 0.48 1.27e-8 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs4332037 0.851 rs34040190 chr7:1920356 G/A cg25206134 chr2:45395956 NA 1.13 9.57 0.65 1.42e-16 Bipolar disorder; TGCT cis rs66561647 0.634 rs7387606 chr8:128929371 A/G cg11792826 chr8:129160931 MIR1208 0.22 5.11 0.42 1.21e-6 Hemoglobin concentration; TGCT cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg26531700 chr6:26746687 NA 0.51 4.71 0.39 6.4e-6 Intelligence (multi-trait analysis); TGCT cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 6.09 0.48 1.32e-8 Mean platelet volume; TGCT cis rs2050392 0.517 rs593400 chr10:30762088 A/G cg18806716 chr10:30721971 MAP3K8 0.45 5.35 0.43 4.02e-7 Inflammatory bowel disease; TGCT cis rs3125734 0.633 rs10761616 chr10:64009076 G/A cg09941381 chr10:64027924 RTKN2 -0.37 -5.59 -0.45 1.41e-7 Rheumatoid arthritis; TGCT cis rs2933343 0.700 rs789240 chr3:128630635 T/C cg11901034 chr3:128598214 ACAD9 -0.63 -6.05 -0.48 1.61e-8 IgG glycosylation; TGCT cis rs6733011 0.578 rs1581250 chr2:99500750 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.76 -0.39 5.3e-6 Bipolar disorder; TGCT cis rs700590 0.683 rs304152 chr5:88124123 A/C cg22951263 chr5:87985283 NA 0.56 5.38 0.43 3.64e-7 Educational attainment (years of education); TGCT cis rs892961 0.932 rs9646396 chr17:75416755 G/A cg05865280 chr17:75406074 SEPT9 0.28 6.42 0.5 2.62e-9 Airflow obstruction; TGCT trans rs1814175 0.502 rs12365889 chr11:49623034 G/A cg11707556 chr5:10655725 ANKRD33B -0.42 -8.47 -0.61 6.09e-14 Height; TGCT cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg22105103 chr4:187893119 NA 0.33 4.62 0.38 9.41e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2594989 0.887 rs2442799 chr3:11488640 A/G cg26283222 chr3:11613257 VGLL4 -0.21 -4.56 -0.38 1.21e-5 Circulating chemerin levels; TGCT cis rs2302464 1.000 rs73123615 chr4:15728176 G/A cg18497811 chr4:14860861 NA -0.49 -4.5 -0.37 1.57e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs13256369 1.000 rs13266699 chr8:8570313 A/T cg17143192 chr8:8559678 CLDN23 -0.58 -5.56 -0.45 1.56e-7 Obesity-related traits; TGCT cis rs13082711 0.522 rs9310842 chr3:27369765 A/T cg02860705 chr3:27208620 NA -0.29 -4.57 -0.38 1.15e-5 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs860295 0.529 rs17381047 chr1:155983648 G/A cg05700447 chr1:155978627 NA -0.19 -4.68 -0.39 7.49e-6 Body mass index; TGCT cis rs1059312 0.808 rs11059921 chr12:129289919 C/T cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs9787249 0.957 rs41267029 chr1:40214367 A/G cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs2153535 0.580 rs7742689 chr6:8452433 C/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs9296092 0.538 rs56199698 chr6:33534505 G/C cg13560919 chr6:33536144 NA -0.23 -4.95 -0.41 2.4e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs16958440 0.867 rs75287977 chr18:44686823 G/A cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs137699 1.000 rs5757630 chr22:39754433 G/T cg11247378 chr22:39784982 NA -0.45 -4.79 -0.39 4.77e-6 IgG glycosylation; TGCT cis rs4366490 0.687 rs4963249 chr11:62905159 C/G cg21002970 chr11:62369079 MTA2 0.74 5.2 0.42 7.81e-7 Conotruncal heart defects; TGCT cis rs10832963 1.000 rs10832963 chr11:18664241 T/G cg20219074 chr11:18656078 SPTY2D1 0.98 9.82 0.66 3.4e-17 Breast cancer; TGCT cis rs9818758 0.607 rs11706189 chr3:49210833 C/A cg00383909 chr3:49044727 WDR6 1.28 6.68 0.51 7.04e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs11098499 0.779 rs10011097 chr4:120310359 T/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs45509595 0.841 rs200501 chr6:27788942 C/T cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.24e-6 Breast cancer; TGCT cis rs854765 0.623 rs9893690 chr17:17753846 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.71 -6.8 -0.52 3.97e-10 Total body bone mineral density; TGCT cis rs10504229 0.817 rs10504230 chr8:58197150 A/G cg22535103 chr8:58192502 C8orf71 0.43 5.26 0.43 6e-7 Developmental language disorder (linguistic errors); TGCT cis rs7940866 0.801 rs10894288 chr11:130808679 T/C cg12179176 chr11:130786555 SNX19 0.59 5.89 0.47 3.41e-8 Schizophrenia; TGCT cis rs12478296 1.000 rs66466023 chr2:243046151 T/G cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs3749237 0.615 rs55957735 chr3:49438158 G/A cg03060546 chr3:49711283 APEH 0.77 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs6490294 0.583 rs4767364 chr12:112521448 G/A cg10833066 chr12:111807467 FAM109A 0.34 5.22 0.42 7.39e-7 Mean platelet volume; TGCT cis rs2153535 0.580 rs2143357 chr6:8497196 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs6545883 0.895 rs796597 chr2:61681060 A/G cg15711740 chr2:61764176 XPO1 -0.56 -5.1 -0.42 1.23e-6 Tuberculosis; TGCT cis rs8064299 0.967 rs878905 chr17:72769411 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.79 8.01 0.58 7.17e-13 Monocyte count; TGCT cis rs2288073 0.896 rs13404513 chr2:24410780 G/A cg05570707 chr2:24270316 C2orf44 -0.5 -4.49 -0.37 1.58e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs4700695 1.000 rs3846481 chr5:65417803 T/C cg21114390 chr5:65439923 SFRS12 -0.58 -4.45 -0.37 1.93e-5 Facial morphology (factor 19); TGCT cis rs7412746 0.658 rs6656535 chr1:150940357 G/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.72 0.39 6.28e-6 Melanoma; TGCT cis rs523522 0.892 rs4767916 chr12:121024032 T/C cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs988712 0.705 rs4923463 chr11:27672500 A/G cg10635145 chr11:27742435 BDNF -0.38 -5.25 -0.43 6.38e-7 Obesity; TGCT cis rs2806561 0.704 rs667330 chr1:23515257 A/G cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs12497850 0.897 rs7373778 chr3:48836392 C/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs9911578 0.900 rs4793593 chr17:56892699 C/G cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg00149659 chr3:10157352 C3orf10 -0.91 -5.89 -0.47 3.32e-8 Alzheimer's disease; TGCT cis rs78487399 0.908 rs17031095 chr2:43819139 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs765787 0.530 rs11634794 chr15:45534492 A/C cg24006582 chr15:45444508 DUOX1 -0.24 -5.28 -0.43 5.51e-7 Uric acid levels; TGCT cis rs3785574 0.927 rs2727313 chr17:61961914 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.07 11.85 0.73 4.07e-22 Height; TGCT cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.38 -6.37 -0.5 3.4e-9 Schizophrenia; TGCT cis rs13191362 1.000 rs7764785 chr6:163009967 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7582180 0.627 rs2099611 chr2:101021090 A/G cg08017756 chr2:100939284 LONRF2 -0.31 -5.02 -0.41 1.72e-6 Intelligence (multi-trait analysis); TGCT cis rs17401966 0.838 rs7553935 chr1:10375179 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.38 -0.44 3.56e-7 Hepatocellular carcinoma; TGCT cis rs1552244 1.000 rs112509186 chr3:10156533 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.94 -0.53 1.89e-10 Alzheimer's disease; TGCT cis rs6582630 0.555 rs2090785 chr12:38424342 G/A cg13010199 chr12:38710504 ALG10B 0.59 4.79 0.4 4.67e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg03396347 chr1:1875803 NA -0.36 -6.58 -0.51 1.19e-9 Body mass index; TGCT cis rs6831352 0.505 rs11722561 chr4:100088737 T/A cg12011299 chr4:100065546 ADH4 0.35 5.14 0.42 1.03e-6 Alcohol dependence; TGCT cis rs11690935 0.918 rs11757 chr2:172641045 C/G cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.83 -0.76 1.7e-24 Schizophrenia; TGCT cis rs9911578 0.967 rs2333410 chr17:57137129 G/A cg05425664 chr17:57184151 TRIM37 0.68 6.9 0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs763014 0.966 rs7198877 chr16:661439 A/G cg07343612 chr16:622815 PIGQ -0.42 -8.44 -0.6 7.14e-14 Height; TGCT cis rs2458413 0.500 rs2458415 chr8:105351998 A/C cg04554929 chr8:105342491 NA 0.5 6.07 0.48 1.42e-8 Paget's disease; TGCT cis rs6952808 0.965 rs4719318 chr7:1887930 G/A cg22963979 chr7:1858916 MAD1L1 -0.32 -4.95 -0.41 2.39e-6 Bipolar disorder and schizophrenia; TGCT cis rs12615966 0.651 rs72830471 chr2:105407062 A/C cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs9549367 0.789 rs6577034 chr13:113879900 T/C cg00898013 chr13:113819073 PROZ -0.41 -5.21 -0.42 7.7300000000000005e-07 Platelet distribution width; TGCT cis rs78545713 0.892 rs113432940 chr6:26256324 T/A cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.66 -4.77 -0.39 5.17e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs9467711 0.651 rs34197618 chr6:26083519 T/C cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs7824557 0.603 rs2246606 chr8:11219334 G/A cg21775007 chr8:11205619 TDH 0.64 5.92 0.47 2.97e-8 Retinal vascular caliber; TGCT cis rs6785206 0.504 rs34992870 chr3:128503052 A/G cg25356066 chr3:128598488 ACAD9 -0.78 -4.45 -0.37 1.91e-5 Lymphocyte percentage of white cells; TGCT cis rs2204008 0.775 rs2387809 chr12:38363338 T/A cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.44e-11 Bladder cancer; TGCT cis rs9894429 0.646 rs7217415 chr17:79618252 G/A cg21028142 chr17:79581711 NPLOC4 0.29 5.85 0.46 4.18e-8 Eye color traits; TGCT cis rs7587476 0.531 rs35933323 chr2:215674090 T/G cg04004882 chr2:215674386 BARD1 -0.65 -5.13 -0.42 1.09e-6 Neuroblastoma; TGCT cis rs35146811 0.695 rs1623264 chr7:99811204 G/C cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs3087591 0.919 rs2072131 chr17:29559588 G/C cg24425628 chr17:29625626 OMG;NF1 -0.46 -7.32 -0.55 2.68e-11 Hip circumference; TGCT cis rs10779751 0.734 rs2259886 chr1:11137778 C/T cg08854313 chr1:11322531 MTOR 0.84 8.3 0.6 1.47e-13 Body mass index; TGCT cis rs17125944 0.505 rs77690283 chr14:53233320 C/G cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs610932 0.517 rs670854 chr11:59981769 T/C cg18570331 chr11:60101691 MS4A6E 0.52 4.84 0.4 3.79e-6 Alzheimer's disease; TGCT cis rs9388451 0.839 rs9401845 chr6:126104118 A/G cg10911889 chr6:126070802 HEY2 0.51 5.33 0.43 4.47e-7 Brugada syndrome; TGCT cis rs453301 0.686 rs3895823 chr8:8873646 T/C cg06636001 chr8:8085503 FLJ10661 -0.68 -5.63 -0.45 1.13e-7 Joint mobility (Beighton score); TGCT cis rs595982 0.527 rs73061656 chr19:49372355 G/A cg21252483 chr19:49399788 TULP2 -0.42 -6.36 -0.5 3.58e-9 Red cell distribution width; TGCT cis rs8179 1.000 rs8179 chr7:92236164 T/C cg15732164 chr7:92237376 CDK6 0.33 4.9 0.4 2.99e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs7666738 0.830 rs4699595 chr4:99012827 A/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11167764 1.000 rs6887599 chr5:141484349 G/A cg23435118 chr5:141488016 NDFIP1 -0.3 -5.04 -0.41 1.61e-6 Crohn's disease; TGCT cis rs826838 0.967 rs826856 chr12:39115434 G/A cg13010199 chr12:38710504 ALG10B -0.64 -5.07 -0.41 1.39e-6 Heart rate; TGCT cis rs9473924 0.505 rs7738924 chr6:50850600 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs769267 0.965 rs13964 chr19:19468710 C/G cg19010396 chr19:19431384 KIAA0892;SF4 -0.56 -4.58 -0.38 1.13e-5 Tonsillectomy; TGCT cis rs7246657 0.943 rs10414904 chr19:37830088 G/A cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.31e-7 Coronary artery calcification; TGCT cis rs7826238 0.509 rs2948288 chr8:8115304 A/G cg08975724 chr8:8085496 FLJ10661 0.64 6.07 0.48 1.44e-8 Systolic blood pressure; TGCT cis rs9300255 0.510 rs1790109 chr12:123637752 C/G cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs2072499 0.966 rs2984615 chr1:156165317 G/C cg25208724 chr1:156163844 SLC25A44 1.14 17.15 0.84 1.56e-34 Testicular germ cell tumor; TGCT cis rs1372520 0.935 rs1442152 chr4:90775649 C/A cg15133208 chr4:90757351 SNCA -0.5 -5.9 -0.47 3.18e-8 Neuroticism; TGCT cis rs473651 0.935 rs541013 chr2:239336492 G/A cg08773314 chr2:239334832 ASB1 0.47 7.87 0.58 1.54e-12 Multiple system atrophy; TGCT cis rs3015497 0.616 rs1389650 chr14:51081449 C/T cg04730355 chr14:51134070 SAV1 -0.64 -6.14 -0.48 1.01e-8 Mean platelet volume; TGCT cis rs7674212 0.556 rs13151569 chr4:103942790 A/G cg16532752 chr4:104119610 CENPE -0.56 -4.92 -0.4 2.64e-6 Type 2 diabetes; TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg11003573 chr3:44754125 ZNF502 -0.47 -5.44 -0.44 2.76e-7 Depressive symptoms; TGCT cis rs7949030 0.591 rs12049914 chr11:62369436 C/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.48 0.65 2.35e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg02353165 chr6:42928485 GNMT 0.99 10.14 0.67 5.89e-18 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2708977 0.933 rs2579502 chr2:97198800 A/G cg01950434 chr2:97203154 ARID5A -0.7 -6.42 -0.5 2.68e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT trans rs561341 0.941 rs4795664 chr17:30233467 C/T cg20587970 chr11:113659929 NA -0.82 -9.73 -0.66 5.87e-17 Hip circumference adjusted for BMI; TGCT cis rs7119 0.651 rs8025968 chr15:77839616 C/T cg27398640 chr15:77910606 LINGO1 -0.28 -5.12 -0.42 1.13e-6 Type 2 diabetes; TGCT cis rs2932538 0.922 rs6691917 chr1:113137043 G/C cg22162597 chr1:113214053 CAPZA1 0.25 5.6 0.45 1.34e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs12477438 0.520 rs13030961 chr2:99799520 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.31 0.77 1.16e-25 Chronic sinus infection; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg26668828 chr6:292823 DUSP22 0.79 8.26 0.6 1.83e-13 Menopause (age at onset); TGCT cis rs7147624 1.000 rs61987807 chr14:66207050 G/T cg03016385 chr14:66212404 NA -0.5 -7.11 -0.54 8.15e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg11062466 chr8:58055876 NA 0.43 4.64 0.38 8.85e-6 Developmental language disorder (linguistic errors); TGCT cis rs9790314 0.936 rs336572 chr3:161068014 G/A cg03342759 chr3:160939853 NMD3 -0.47 -4.8 -0.4 4.55e-6 Morning vs. evening chronotype; TGCT cis rs9972944 0.756 rs9894298 chr17:63769225 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs8031584 0.678 rs798127 chr15:31117403 T/C cg08704250 chr15:31115839 NA 0.44 6.43 0.5 2.47e-9 Huntington's disease progression; TGCT cis rs10193935 0.901 rs13375 chr2:42559288 A/G cg27598129 chr2:42591480 NA -0.38 -5.22 -0.42 7.42e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs60154123 0.505 rs2206043 chr1:210042983 G/A cg12034118 chr1:209979487 IRF6 0.65 4.56 0.38 1.2e-5 Coronary artery disease; TGCT cis rs7666738 0.830 rs17027090 chr4:98897923 G/T cg17366294 chr4:99064904 C4orf37 0.67 6.83 0.52 3.3e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7829975 0.624 rs7823056 chr8:8382705 A/G cg08975724 chr8:8085496 FLJ10661 0.64 6.07 0.48 1.45e-8 Mood instability; TGCT cis rs17681684 0.541 rs12150176 chr17:9764547 C/T cg15743799 chr17:9805578 RCVRN -0.27 -5.8 -0.46 5.29e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs9522267 0.737 rs7330902 chr13:112227599 C/T cg10483660 chr13:112241077 NA -0.29 -4.7 -0.39 6.81e-6 Hepatitis; TGCT cis rs6964587 0.692 rs4729025 chr7:91847504 C/T cg17063962 chr7:91808500 NA 0.77 7.17 0.54 6.08e-11 Breast cancer; TGCT cis rs908922 0.676 rs7530609 chr1:152526812 C/A cg20991723 chr1:152506922 NA 0.45 6.06 0.48 1.55e-8 Hair morphology; TGCT cis rs72634258 0.503 rs697674 chr1:7837878 C/G cg26816564 chr1:7831052 VAMP3 0.98 7.19 0.54 5.47e-11 Inflammatory bowel disease; TGCT cis rs10927875 0.541 rs1048237 chr1:16341733 T/C cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs3020736 0.500 rs6519306 chr22:42501217 T/C cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs35883536 0.588 rs12568329 chr1:101104588 A/G cg06223162 chr1:101003688 GPR88 -0.32 -5.34 -0.43 4.31e-7 Monocyte count; TGCT cis rs1008375 1.000 rs1006722 chr4:17618713 A/G cg16339924 chr4:17578868 LAP3 -0.61 -5.03 -0.41 1.65e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7246657 0.638 rs7246461 chr19:38196581 C/G cg18154014 chr19:37997991 ZNF793 -0.63 -4.55 -0.38 1.24e-5 Coronary artery calcification; TGCT cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg15691649 chr6:25882328 NA 0.43 5.34 0.43 4.27e-7 Blood metabolite levels; TGCT cis rs12765878 1.000 rs4918068 chr10:105644736 T/G cg11005552 chr10:105648138 OBFC1 0.45 7.89 0.58 1.36e-12 Coronary artery disease; TGCT cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg17971929 chr21:40555470 PSMG1 0.97 9.4 0.65 3.57e-16 Cognitive function; TGCT cis rs7917772 0.636 rs7911747 chr10:104528890 A/G cg05855489 chr10:104503620 C10orf26 0.64 5.11 0.42 1.19e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8014204 0.836 rs7153700 chr14:75268544 C/T cg06637938 chr14:75390232 RPS6KL1 0.67 6.53 0.51 1.55e-9 Caffeine consumption; TGCT cis rs1403694 0.655 rs3806688 chr3:186434819 T/C cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs704 0.752 rs6505079 chr17:26718177 T/A cg10342447 chr17:26645325 TMEM97 -0.51 -4.91 -0.4 2.82e-6 Osteoprotegerin levels; TGCT cis rs1552244 0.572 rs66514627 chr3:10166632 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs950776 0.722 rs471889 chr15:78870235 T/C cg06917634 chr15:78832804 PSMA4 -0.66 -5.29 -0.43 5.47e-7 Sudden cardiac arrest; TGCT cis rs11719291 0.667 rs9877542 chr3:48748545 C/T cg00383909 chr3:49044727 WDR6 0.98 5.67 0.45 9.63e-8 Cognitive function; TGCT cis rs2153535 0.580 rs1577472 chr6:8486215 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9814567 0.929 rs9855013 chr3:134240414 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs12579753 0.879 rs7971664 chr12:82264101 T/C cg07988820 chr12:82153109 PPFIA2 -0.52 -5.44 -0.44 2.69e-7 Resting heart rate; TGCT cis rs10426930 0.547 rs2054519 chr19:5059360 T/C cg09001777 chr19:5851504 FUT3 -0.2 -4.5 -0.37 1.57e-5 Monocyte percentage of white cells; TGCT cis rs11190604 1.000 rs10883492 chr10:102206089 G/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1532993 0.518 rs6825353 chr4:98604203 G/A cg05340658 chr4:99064831 C4orf37 -0.37 -4.44 -0.37 1.98e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs4642101 0.561 rs7641959 chr3:12810755 G/C cg05775895 chr3:12838266 CAND2 0.51 5.11 0.42 1.16e-6 QRS complex (12-leadsum); TGCT cis rs72781680 1.000 rs72796316 chr2:24132272 T/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs4319547 0.656 rs10161534 chr12:122873864 T/C cg05707623 chr12:122985044 ZCCHC8 -0.61 -4.74 -0.39 5.7e-6 Body mass index; TGCT cis rs4372836 0.543 rs10204329 chr2:28998077 C/G cg09522027 chr2:28974177 PPP1CB -0.75 -7.46 -0.56 1.28e-11 Body mass index; TGCT cis rs11122272 0.735 rs1416916 chr1:231533027 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.53 -0.51 1.55e-9 Hemoglobin concentration; TGCT cis rs6912958 0.712 rs4498321 chr6:88339251 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs67311347 0.544 rs12635762 chr3:40332759 C/T cg13683864 chr3:40499215 RPL14 0.78 7.24 0.54 4.19e-11 Renal cell carcinoma; TGCT cis rs3087591 0.960 rs10512433 chr17:29600564 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 7.28 0.55 3.41e-11 Hip circumference; TGCT cis rs7172809 0.643 rs75334741 chr15:77841492 T/C cg22256960 chr15:77711686 NA -0.47 -4.62 -0.38 9.37e-6 Glucose homeostasis traits; TGCT cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs2404602 0.608 rs17361504 chr15:76601871 A/G cg26408565 chr15:76604113 ETFA -0.47 -6.5 -0.5 1.73e-9 Blood metabolite levels; TGCT cis rs4975709 0.610 rs1531994 chr5:1859297 T/C cg12288994 chr5:1860383 NA 0.24 4.52 0.38 1.42e-5 Cardiovascular disease risk factors; TGCT cis rs860295 0.580 rs867549 chr1:155880159 T/C cg13795986 chr1:155880507 RIT1 0.38 4.59 0.38 1.05e-5 Body mass index; TGCT cis rs7027203 0.828 rs10761288 chr9:96609363 C/T cg14598338 chr9:96623480 NA -0.58 -8.53 -0.61 4.27e-14 DNA methylation (variation); TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg13397359 chr6:42928475 GNMT 0.69 6.21 0.49 7.39e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6815814 0.861 rs17616434 chr4:38812876 T/C cg02016764 chr4:38805732 TLR1 -0.28 -4.84 -0.4 3.73e-6 Breast cancer; TGCT cis rs2404602 0.608 rs12911035 chr15:76606591 T/C cg22467129 chr15:76604101 ETFA -0.61 -7.93 -0.58 1.1e-12 Blood metabolite levels; TGCT cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.65 0.39 8.4e-6 Renal cell carcinoma; TGCT cis rs7267979 1.000 rs7343481 chr20:25300113 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg20007245 chr22:24372913 LOC391322 -0.69 -6.27 -0.49 5.45e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs765787 0.556 rs10851422 chr15:45513738 T/C cg24006582 chr15:45444508 DUOX1 0.25 5.37 0.43 3.76e-7 Uric acid levels; TGCT cis rs57221529 0.709 rs72707023 chr5:667620 G/A cg09021430 chr5:549028 NA -0.4 -5.49 -0.44 2.14e-7 Lung disease severity in cystic fibrosis; TGCT cis rs526231 0.543 rs6881225 chr5:102307592 T/C cg23492399 chr5:102201601 PAM -0.53 -4.56 -0.38 1.23e-5 Primary biliary cholangitis; TGCT cis rs5417 0.610 rs222843 chr17:7145981 T/C cg25256661 chr17:7137939 DVL2 0.76 7.17 0.54 5.96e-11 Diastolic blood pressure; TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs6952808 0.600 rs2895202 chr7:2131829 T/C cg04267008 chr7:1944627 MAD1L1 -0.35 -4.65 -0.39 8.28e-6 Bipolar disorder and schizophrenia; TGCT cis rs924607 1.000 rs2455331 chr5:643593 T/C cg18765565 chr5:669397 TPPP 0.59 6.33 0.49 4.16e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs6912958 0.535 rs1753154 chr6:88032843 G/C cg08069147 chr6:88032118 GJB7;C6orf162 0.72 7.32 0.55 2.77e-11 Monocyte percentage of white cells; TGCT cis rs2288278 0.646 rs10514953 chr17:46589258 C/G cg25032089 chr17:46643351 HOXB3 -0.41 -4.8 -0.4 4.55e-6 Hand grip strength; TGCT cis rs12468226 1.000 rs77435512 chr2:203198888 G/C cg26506821 chr2:202639771 ALS2 0.33 4.57 0.38 1.17e-5 Urate levels; TGCT cis rs3125734 0.633 rs1873685 chr10:64032126 C/T cg05499367 chr10:63213510 TMEM26 -0.33 -4.49 -0.37 1.62e-5 Rheumatoid arthritis; TGCT cis rs425277 0.606 rs424079 chr1:2071340 C/A cg24578937 chr1:2090814 PRKCZ -0.25 -6.39 -0.5 2.97e-9 Height; TGCT cis rs7804356 0.520 rs10255249 chr7:26809963 A/G cg03456212 chr7:26904342 SKAP2 -0.5 -4.44 -0.37 2e-5 Type 1 diabetes; TGCT cis rs8038465 0.622 rs62004587 chr15:73859016 A/C cg15420318 chr15:73925796 NPTN 0.63 6.65 0.51 8.32e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9611519 1.000 rs2057070 chr22:41564287 T/C cg03806693 chr22:41940476 POLR3H -0.67 -6.19 -0.49 7.94e-9 Neuroticism; TGCT cis rs7904368 0.754 rs7076779 chr10:16852667 C/T cg23933602 chr10:16859644 RSU1 0.63 4.83 0.4 3.91e-6 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs9341808 0.667 rs2322632 chr6:80845608 G/A cg08355045 chr6:80787529 NA 0.31 5.31 0.43 4.96e-7 Sitting height ratio; TGCT cis rs2842992 0.915 rs2758335 chr6:160111011 G/A cg11366901 chr6:160182831 ACAT2 0.94 6.18 0.49 8.48e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg01585852 chr22:24235823 MIF -0.21 -4.56 -0.38 1.23e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg11644478 chr21:40555479 PSMG1 1.02 10.93 0.7 6.95e-20 Cognitive function; TGCT cis rs9393692 0.905 rs9358919 chr6:26287862 C/T cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.11e-7 Educational attainment; TGCT cis rs7926906 1.000 rs10741377 chr11:90539430 T/A cg26138821 chr11:89956704 CHORDC1 -0.47 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis); TGCT cis rs8042680 0.554 rs59902579 chr15:91515489 C/T cg22570213 chr15:91497863 RCCD1 0.44 4.69 0.39 7.23e-6 Type 2 diabetes; TGCT cis rs7666738 0.830 rs10012271 chr4:99065154 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3796352 1.000 rs11718752 chr3:53130745 T/C cg07884673 chr3:53033167 SFMBT1 0.49 5.11 0.42 1.16e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs801193 1.000 rs2707854 chr7:66212597 G/A cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.97e-7 Aortic root size; TGCT cis rs8078723 0.714 rs9915252 chr17:38145088 C/G cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.69e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7267979 0.844 rs6083845 chr20:25388090 G/C cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11716531 0.574 rs62256311 chr3:27271505 G/A cg02860705 chr3:27208620 NA 0.45 7.0 0.53 1.45e-10 Diastolic blood pressure; TGCT cis rs17376456 0.877 rs7702521 chr5:93484579 G/T cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.21e-14 Diabetic retinopathy; TGCT cis rs78456975 0.568 rs115482599 chr2:1571960 A/G cg01028140 chr2:1542097 TPO -0.31 -4.67 -0.39 7.59e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs17197710 0.673 rs3816724 chr11:47312045 C/G cg13308137 chr11:47528955 CUGBP1 -0.41 -5.82 -0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9303401 0.614 rs28651036 chr17:57080471 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.95 0.47 2.59e-8 Cognitive test performance; TGCT cis rs7681440 0.835 rs1899389 chr4:90802998 G/A cg26578617 chr4:90757533 SNCA -0.45 -4.63 -0.38 9.12e-6 Dementia with Lewy bodies; TGCT cis rs13191362 1.000 rs34918316 chr6:163005386 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs921968 0.643 rs613539 chr2:219455967 G/T cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT trans rs57221529 0.766 rs72706608 chr5:559203 C/T cg25482853 chr8:67687455 SGK3 1.2 10.16 0.67 5.25e-18 Lung disease severity in cystic fibrosis; TGCT cis rs10479542 0.766 rs6894980 chr5:178974592 C/T cg14820908 chr5:178986412 RUFY1 0.45 4.63 0.38 9.19e-6 Lung cancer; TGCT cis rs1355223 0.583 rs2915178 chr11:34878051 C/T cg11058730 chr11:34937778 PDHX;APIP 0.77 8.26 0.6 1.87e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg08280861 chr8:58055591 NA -0.52 -5.89 -0.47 3.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs11148252 0.774 rs9596649 chr13:52934610 A/G cg02158880 chr13:53174818 NA -0.38 -4.57 -0.38 1.17e-5 Lewy body disease; TGCT cis rs9868809 0.772 rs73078349 chr3:48688114 G/A cg00383909 chr3:49044727 WDR6 1.29 6.0 0.47 2.04e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7258465 1.000 rs10164319 chr19:18569833 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.51 0.38 1.5e-5 Breast cancer; TGCT cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg19635926 chr16:89946313 TCF25 0.29 4.84 0.4 3.84e-6 Skin colour saturation; TGCT cis rs7336332 0.527 rs1475219 chr13:28037415 A/G cg22138327 chr13:27999177 GTF3A 0.68 5.26 0.43 6.25e-7 Weight; TGCT cis rs17376456 0.825 rs6898842 chr5:93213221 T/C cg21475434 chr5:93447410 FAM172A 0.7 4.86 0.4 3.51e-6 Diabetic retinopathy; TGCT cis rs739496 0.579 rs12307365 chr12:112290651 G/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs36051895 0.659 rs58345215 chr9:5043767 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.64 -0.65 9.46e-17 Pediatric autoimmune diseases; TGCT cis rs9560113 0.508 rs2774425 chr13:112235077 A/G cg10483660 chr13:112241077 NA -0.32 -5.13 -0.42 1.09e-6 Menarche (age at onset); TGCT cis rs916888 0.779 rs430685 chr17:44859148 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4455778 0.580 rs10261034 chr7:49092554 C/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7582180 0.764 rs7425797 chr2:100928337 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.91 -0.4 2.81e-6 Intelligence (multi-trait analysis); TGCT cis rs909002 1.000 rs1474182 chr1:32136398 C/T cg11573219 chr1:32083031 HCRTR1 -0.37 -4.71 -0.39 6.42e-6 Intelligence (multi-trait analysis); TGCT cis rs7914558 0.966 rs12569617 chr10:104729996 T/C cg15744005 chr10:104629667 AS3MT -0.4 -4.93 -0.41 2.55e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs854624 0.892 rs1734959 chr17:34336510 A/G cg02022384 chr17:34097390 MMP28 0.49 4.55 0.38 1.28e-5 Blood protein levels; TGCT cis rs79349575 0.749 rs8182364 chr17:47018025 A/G cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs12477438 0.765 rs2309520 chr2:99570477 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.53 4.68 0.39 7.41e-6 Chronic sinus infection; TGCT cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg05552183 chr6:42928497 GNMT 0.57 5.54 0.45 1.72e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs546131 0.642 rs561477 chr11:34852152 G/A cg06937548 chr11:34938143 PDHX;APIP 0.52 4.55 0.38 1.24e-5 Lung disease severity in cystic fibrosis; TGCT cis rs2073300 1.000 rs79169006 chr20:23443535 A/T cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs10504229 0.769 rs17215649 chr8:58152791 A/G cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs78456975 1.000 rs11899027 chr2:1560414 G/C cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2798269 0.544 rs1200030 chr13:22160604 C/T cg18095732 chr13:22033692 ZDHHC20 -0.5 -4.46 -0.37 1.83e-5 PR segment; TGCT cis rs6840360 0.593 rs4696107 chr4:152606823 G/A cg17479576 chr4:152424074 FAM160A1 -0.62 -6.23 -0.49 6.69e-9 Intelligence (multi-trait analysis); TGCT cis rs4563143 0.514 rs112540771 chr19:29316100 C/T cg04546413 chr19:29218101 NA 0.7 5.05 0.41 1.54e-6 Methadone dose in opioid dependence; TGCT cis rs6062496 0.631 rs2297436 chr20:62304178 G/C cg27236539 chr20:62289627 RTEL1 0.69 6.52 0.51 1.59e-9 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg12310025 chr6:25882481 NA -0.91 -8.67 -0.61 2.01e-14 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.798 rs1530996 chr2:99584079 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.87 -8.79 -0.62 1.04e-14 Chronic sinus infection; TGCT cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4906332 0.966 rs17679729 chr14:103924312 A/G cg26031613 chr14:104095156 KLC1 -0.53 -4.71 -0.39 6.62e-6 Coronary artery disease; TGCT cis rs3806843 1.000 rs9686540 chr5:140174622 G/A cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7267979 0.816 rs390123 chr20:25480105 C/G cg03522245 chr20:25566470 NINL 0.56 5.79 0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7926906 0.817 rs7941948 chr11:90527549 C/T cg22332266 chr11:89956777 CHORDC1 -0.42 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis); TGCT cis rs4654899 0.772 rs951805 chr1:21060356 A/G cg01072550 chr1:21505969 NA 0.47 7.19 0.54 5.38e-11 Superior frontal gyrus grey matter volume; TGCT cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg16524733 chr11:117070046 TAGLN 0.33 4.9 0.4 2.87e-6 Blood protein levels; TGCT cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs9926296 0.632 rs7184315 chr16:89799373 C/G cg27121462 chr16:89883253 FANCA -0.54 -5.11 -0.42 1.2e-6 Vitiligo; TGCT cis rs12188164 1.000 rs12188164 chr5:428236 C/A cg21144161 chr5:423903 AHRR 0.24 4.5 0.37 1.53e-5 Cystic fibrosis severity; TGCT cis rs950169 0.519 rs7237 chr15:85186577 C/T cg12863693 chr15:85201151 NMB 0.42 5.19 0.42 8.48e-7 Schizophrenia; TGCT cis rs1552244 0.515 rs67342818 chr3:10166406 G/A cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs12711979 0.740 rs6711963 chr2:3820915 A/T cg17052675 chr2:3827356 NA -0.4 -7.82 -0.57 2.02e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs709400 0.827 rs2274269 chr14:104029246 G/A cg26031613 chr14:104095156 KLC1 1.15 14.5 0.79 1.83e-28 Body mass index; TGCT cis rs9611565 0.559 rs5758397 chr22:42019251 C/T cg06481639 chr22:41940642 POLR3H 0.73 6.47 0.5 2.04e-9 Vitiligo; TGCT cis rs7805747 0.523 rs13239239 chr7:151423196 C/T cg17611936 chr7:151411526 PRKAG2 -0.39 -4.53 -0.38 1.37e-5 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs12421382 0.659 rs12417251 chr11:109386273 G/T cg16359550 chr11:109292809 C11orf87 0.4 4.49 0.37 1.61e-5 Schizophrenia; TGCT cis rs11098499 0.954 rs17005535 chr4:120411562 C/T cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs4919044 0.808 rs835274 chr10:94796534 A/G cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs2153535 0.540 rs9378557 chr6:8517381 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs903263 1.000 rs12128892 chr1:84624893 G/A cg09664975 chr1:84543551 PRKACB 0.47 4.5 0.37 1.54e-5 Breast cancer (male); TGCT cis rs10479542 0.806 rs4700836 chr5:178976393 A/G cg21226059 chr5:178986404 RUFY1 0.44 4.74 0.39 5.79e-6 Lung cancer; TGCT cis rs6951245 0.872 rs77569514 chr7:1085508 G/A cg27454412 chr7:1067447 C7orf50 0.57 4.48 0.37 1.71e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10501293 0.666 rs7118471 chr11:43005512 T/C cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.2e-9 Cognitive performance; TGCT cis rs9311474 0.581 rs13621 chr3:52558133 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.91 0.4 2.75e-6 Electroencephalogram traits; TGCT cis rs9443645 0.901 rs1960542 chr6:79566643 C/T cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.31e-7 Intelligence (multi-trait analysis); TGCT cis rs854765 0.927 rs4925138 chr17:17992793 T/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.63 -5.95 -0.47 2.54e-8 Total body bone mineral density; TGCT cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg18230493 chr5:56204884 C5orf35 -0.66 -5.65 -0.45 1.05e-7 Initial pursuit acceleration; TGCT cis rs9916302 0.904 rs8081338 chr17:37406139 C/T cg07936489 chr17:37558343 FBXL20 -0.65 -5.24 -0.43 6.62e-7 Glomerular filtration rate (creatinine); TGCT cis rs7647973 1.000 rs3905330 chr3:49550774 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.76 -0.39 5.24e-6 Menarche (age at onset); TGCT cis rs7727544 0.507 rs10051679 chr5:131570931 T/A cg24060327 chr5:131705240 SLC22A5 -0.58 -6.06 -0.48 1.51e-8 Blood metabolite levels; TGCT trans rs1814175 0.645 rs1874969 chr11:49826700 G/A cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs9611519 1.000 rs3818003 chr22:41609690 C/T cg03806693 chr22:41940476 POLR3H -0.66 -6.3 -0.49 4.65e-9 Neuroticism; TGCT cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg10802521 chr3:52805072 NEK4 -0.74 -9.61 -0.65 1.14e-16 Bipolar disorder; TGCT cis rs12549902 1.000 rs12549902 chr8:41509259 C/T cg21772509 chr8:41503840 NKX6-3 0.87 10.06 0.67 9.27e-18 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs6674176 0.593 rs3791120 chr1:44431715 T/C cg12908607 chr1:44402522 ARTN -0.67 -8.15 -0.59 3.4e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg00149659 chr3:10157352 C3orf10 0.93 6.0 0.47 2.05e-8 Alzheimer's disease; TGCT cis rs290268 1.000 rs290271 chr9:93551619 G/A cg02608019 chr9:93564028 SYK 0.48 4.82 0.4 4.19e-6 Platelet count; TGCT cis rs7726839 0.540 rs28364691 chr5:664084 G/A cg16624210 chr5:671434 TPPP 0.42 4.89 0.4 3.06e-6 Obesity-related traits; TGCT cis rs2832191 0.791 rs9983651 chr21:30491227 T/A cg24692254 chr21:30365293 RNF160 -0.92 -9.97 -0.67 1.45e-17 Dental caries; TGCT cis rs9512730 0.553 rs1007701 chr13:28049143 C/G cg04070771 chr13:27998621 GTF3A -0.53 -4.64 -0.38 8.87e-6 Schizophrenia; TGCT cis rs2880765 0.545 rs11631739 chr15:86012578 T/C cg13263323 chr15:86062960 AKAP13 -0.22 -4.93 -0.41 2.53e-6 Coronary artery disease; TGCT cis rs7119 0.651 rs35577135 chr15:77840074 C/T cg27398640 chr15:77910606 LINGO1 -0.28 -5.16 -0.42 9.63e-7 Type 2 diabetes; TGCT cis rs4654899 0.772 rs7548269 chr1:21089472 T/C cg01072550 chr1:21505969 NA -0.47 -7.01 -0.53 1.32e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4849845 0.598 rs3933620 chr2:121034936 A/T cg24070213 chr2:121070622 NA 0.35 4.77 0.39 5.13e-6 Mean platelet volume; TGCT cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg05890377 chr2:74357713 NA 0.48 6.58 0.51 1.2e-9 Gestational age at birth (maternal effect); TGCT cis rs1799949 1.000 rs4793215 chr17:41318932 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.91 0.4 2.78e-6 Menopause (age at onset); TGCT cis rs7659604 0.539 rs7660548 chr4:122730821 G/C cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.23e-7 Type 2 diabetes; TGCT cis rs1008375 1.000 rs11722037 chr4:17683811 G/A cg18681998 chr4:17616180 MED28 0.9 10.45 0.68 1e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs752010 0.746 rs10749837 chr1:42089471 T/C cg06885757 chr1:42089581 HIVEP3 0.25 4.56 0.38 1.23e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg11494091 chr17:61959527 GH2 0.43 7.3 0.55 3.05e-11 Height; TGCT cis rs10206020 0.759 rs11903889 chr2:1576601 C/T cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs12579753 0.879 rs11615729 chr12:82128318 T/A cg07988820 chr12:82153109 PPFIA2 -0.68 -7.32 -0.55 2.7e-11 Resting heart rate; TGCT cis rs4849845 0.637 rs62168279 chr2:121026771 T/C cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs10504229 0.775 rs17216236 chr8:58159352 G/A cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs12541335 0.639 rs7834182 chr8:22163112 G/A cg02788857 chr8:22132959 PIWIL2 0.28 5.11 0.42 1.2e-6 Hypertriglyceridemia; TGCT trans rs12001652 0.579 rs7025739 chr9:14017640 A/G cg16456503 chr16:67943052 PSKH1 0.43 6.71 0.52 6.27e-10 Carotid plaque burden; TGCT cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs9560113 1.000 rs9560113 chr13:112183348 A/G cg14154082 chr13:112174009 NA 0.36 4.8 0.4 4.52e-6 Menarche (age at onset); TGCT cis rs1971762 0.563 rs4759284 chr12:54079491 G/A cg16917193 chr12:54089295 NA 1.37 17.65 0.85 1.25e-35 Height; TGCT cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg03452623 chr4:187889614 NA -0.37 -5.7 -0.46 8.2e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs11018874 0.597 rs4268468 chr11:89886284 C/T cg05041596 chr11:89867385 NAALAD2 0.53 5.33 0.43 4.56e-7 White blood cell types; TGCT cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg20607798 chr8:58055168 NA 0.66 5.58 0.45 1.46e-7 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg03806693 chr22:41940476 POLR3H -1.14 -12.51 -0.75 9.93e-24 Vitiligo; TGCT cis rs7611238 0.583 rs12630009 chr3:195046618 G/A cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.94e-6 Body mass index; TGCT cis rs7772486 0.875 rs56181683 chr6:146286620 A/G cg05347473 chr6:146136440 FBXO30 -0.54 -5.18 -0.42 8.61e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4711350 1.000 rs943472 chr6:33738442 T/C cg18005901 chr6:33739558 LEMD2 -0.55 -5.91 -0.47 3.13e-8 Schizophrenia; TGCT trans rs941408 1.000 rs1736184 chr19:2810248 G/A cg22153745 chr1:153894579 GATAD2B -0.67 -7.24 -0.55 4.11e-11 Total cholesterol levels; TGCT cis rs1670533 1.000 rs6837145 chr4:1071067 T/C cg20887711 chr4:1340912 KIAA1530 0.64 5.02 0.41 1.74e-6 Recombination rate (females); TGCT cis rs11098499 0.675 rs11098534 chr4:120556772 T/G cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs6964587 0.934 rs7793861 chr7:91742728 C/G cg22709100 chr7:91322751 NA 0.28 4.61 0.38 9.79e-6 Breast cancer; TGCT cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs6722750 0.870 rs35899183 chr2:64408776 C/G cg22352474 chr2:64371530 PELI1 0.58 5.23 0.43 6.84e-7 Neuroticism; TGCT cis rs7666738 0.830 rs7662218 chr4:98983126 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.683 rs10157120 chr1:53210888 A/G cg08859206 chr1:53392774 SCP2 -0.35 -5.04 -0.41 1.6e-6 Monocyte count; TGCT cis rs4803455 0.565 rs2241713 chr19:41869468 C/G cg09537434 chr19:41945824 ATP5SL 0.56 5.69 0.45 8.78e-8 Migraine;Coronary artery disease; TGCT cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg23283495 chr1:209979779 IRF6 0.65 5.53 0.44 1.81e-7 Cleft lip with or without cleft palate; TGCT cis rs9291683 0.552 rs10939656 chr4:10014646 A/C cg11266682 chr4:10021025 SLC2A9 0.73 10.86 0.7 1.03e-19 Bone mineral density; TGCT cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs2302045 1.000 rs2270044 chr2:242056924 A/G cg03756522 chr2:242788804 NA -0.42 -4.69 -0.39 7.05e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs7618915 0.501 rs10865974 chr3:52718280 A/C cg10802521 chr3:52805072 NEK4 0.79 10.1 0.67 7.29e-18 Bipolar disorder; TGCT cis rs79349575 0.749 rs318093 chr17:46989354 A/G cg07967210 chr17:47022446 SNF8 0.43 6.04 0.48 1.68e-8 Type 2 diabetes; TGCT cis rs597539 0.652 rs569777 chr11:68706848 G/A cg06028808 chr11:68637592 NA 0.54 6.94 0.53 1.93e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10789491 1.000 rs2083485 chr1:47170091 G/C cg15501359 chr1:47185051 KIAA0494 0.82 8.26 0.6 1.82e-13 Response to hepatitis C treatment; TGCT cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs854765 0.647 rs1008135 chr17:18027143 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.71 0.57 3.61e-12 Total body bone mineral density; TGCT cis rs6089829 0.889 rs6090206 chr20:61668363 G/A cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs7584330 0.737 rs1497127 chr2:238369282 A/G cg08992911 chr2:238395768 MLPH 0.57 4.63 0.38 8.96e-6 Prostate cancer; TGCT cis rs858239 0.670 rs3807452 chr7:23162081 C/T cg05602783 chr7:23145260 KLHL7 0.56 4.67 0.39 7.66e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs1577917 1.000 rs1911552 chr6:86638024 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs2836974 0.666 rs4624474 chr21:40686327 T/C cg11890956 chr21:40555474 PSMG1 -0.76 -7.08 -0.54 9.53e-11 Cognitive function; TGCT cis rs7267979 1.000 rs6115140 chr20:25285507 C/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2760061 0.545 rs1636196 chr1:228204030 A/G cg02753203 chr1:228287806 NA 0.39 7.75 0.57 2.79e-12 Diastolic blood pressure; TGCT cis rs4665809 0.878 rs6748745 chr2:26364190 C/T cg22920501 chr2:26401640 FAM59B -0.73 -6.12 -0.48 1.12e-8 Gut microbiome composition (summer); TGCT cis rs6138458 1.000 rs227658 chr20:24932028 A/G cg26195577 chr20:24973756 C20orf3 1.2 12.06 0.73 1.2e-22 Blood protein levels; TGCT trans rs35934224 1.000 rs35934224 chr22:19872645 C/T cg07537964 chr19:3722604 NA 0.76 6.75 0.52 5.17e-10 Glaucoma (primary open-angle); TGCT cis rs4733781 0.965 rs17285138 chr8:131297696 T/A cg16277922 chr8:131349729 ASAP1 0.44 5.71 0.46 7.95e-8 Tuberculosis; TGCT cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs73001065 0.901 rs73004967 chr19:19717056 A/G cg20644253 chr19:19431407 KIAA0892;SF4 1.01 4.57 0.38 1.18e-5 LDL cholesterol; TGCT cis rs875971 0.862 rs11769079 chr7:65842128 G/A cg11764359 chr7:65958608 NA 0.58 5.31 0.43 4.91e-7 Aortic root size; TGCT cis rs7681440 0.904 rs12331318 chr4:90770255 A/G cg01966878 chr4:90757139 SNCA -0.25 -4.5 -0.37 1.57e-5 Dementia with Lewy bodies; TGCT cis rs9926296 0.586 rs1800359 chr16:89805261 A/G cg08627397 chr16:89984028 MC1R -0.32 -5.11 -0.42 1.16e-6 Vitiligo; TGCT cis rs6570726 0.533 rs1832374 chr6:145717752 A/G cg23711669 chr6:146136114 FBXO30 0.6 5.53 0.44 1.82e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg25036284 chr2:26402008 FAM59B 0.6 4.64 0.38 8.63e-6 Gut microbiome composition (summer); TGCT cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg07061783 chr6:25882402 NA -0.67 -6.58 -0.51 1.18e-9 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.61 0.65 1.14e-16 Cognitive function; TGCT cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg02073558 chr3:44770973 ZNF501 0.73 7.31 0.55 2.81e-11 Depressive symptoms; TGCT cis rs7524258 0.903 rs4908609 chr1:7292910 G/A cg07173049 chr1:7289937 CAMTA1 0.32 5.31 0.43 4.88e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs2303745 0.589 rs11882562 chr19:17395055 C/G cg04248312 chr19:17393744 ANKLE1 0.34 5.94 0.47 2.69e-8 Systemic lupus erythematosus; TGCT cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg03264133 chr6:25882463 NA -0.53 -5.53 -0.44 1.81e-7 Blood metabolite levels; TGCT cis rs12681287 0.511 rs4129535 chr8:87524094 G/T cg27223183 chr8:87520930 FAM82B -0.96 -7.03 -0.53 1.21e-10 Caudate activity during reward; TGCT cis rs9659323 1.000 rs9659323 chr1:119504361 A/G cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.4e-6 Body mass index; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg19626725 chr5:178986131 RUFY1 0.55 7.55 0.56 8.39e-12 Lung cancer; TGCT cis rs62380364 0.727 rs797419 chr5:88168955 C/A cg22951263 chr5:87985283 NA 0.5 5.02 0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs854765 0.623 rs9893690 chr17:17753846 A/T cg09796270 chr17:17721594 SREBF1 -0.26 -4.91 -0.4 2.84e-6 Total body bone mineral density; TGCT cis rs9916302 0.861 rs593480 chr17:37453780 A/C cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.566 rs17051356 chr4:120585308 C/T cg09307838 chr4:120376055 NA 0.59 5.42 0.44 3.01e-7 Corneal astigmatism; TGCT cis rs589448 0.538 rs683790 chr12:69751434 T/G cg14784868 chr12:69753453 YEATS4 0.66 5.84 0.46 4.33e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs7193541 0.684 rs9923145 chr16:74686166 G/A cg01733217 chr16:74700730 RFWD3 1.0 13.51 0.77 3.91e-26 Multiple myeloma; TGCT cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT cis rs12681288 0.748 rs7000148 chr8:1016383 G/C cg06709756 chr8:1339049 NA -0.23 -4.57 -0.38 1.17e-5 Schizophrenia; TGCT cis rs1153858 1.000 rs66714503 chr15:45648038 G/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs77633900 0.614 rs7162982 chr15:76961559 G/A cg21673338 chr15:77095150 SCAPER 0.52 5.17 0.42 9.04e-7 Non-glioblastoma glioma;Glioma; TGCT cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg10117171 chr1:25599238 RHD -0.3 -4.92 -0.4 2.69e-6 Erythrocyte sedimentation rate; TGCT cis rs801193 0.548 rs6975044 chr7:66227482 C/T cg11764359 chr7:65958608 NA 0.53 4.64 0.38 8.62e-6 Aortic root size; TGCT cis rs2289681 0.525 rs34637106 chr17:42985772 C/T cg15193461 chr17:42977049 CCDC103;EFTUD2 -0.72 -6.25 -0.49 5.95e-9 Cognitive function; TGCT cis rs854765 0.583 rs8078138 chr17:17811251 C/T cg09796270 chr17:17721594 SREBF1 0.27 5.55 0.45 1.69e-7 Total body bone mineral density; TGCT cis rs9921338 0.961 rs4781055 chr16:11369428 C/T cg00044050 chr16:11439710 C16orf75 -0.9 -6.15 -0.48 9.88e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs5769765 0.773 rs9616378 chr22:50311973 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.23 -12.66 -0.75 4.45e-24 Schizophrenia; TGCT cis rs10892173 0.566 rs111578166 chr11:117666714 G/T cg07621104 chr11:117668040 DSCAML1 0.69 7.61 0.56 5.84e-12 Myopia; TGCT cis rs711245 0.573 rs7570763 chr2:36800589 A/C cg10546459 chr2:36825355 FEZ2 -0.6 -5.58 -0.45 1.42e-7 Height; TGCT cis rs3796352 1.000 rs11710707 chr3:52975916 A/G cg07884673 chr3:53033167 SFMBT1 0.63 5.74 0.46 6.83e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2299433 0.627 rs62469056 chr7:116336013 G/A cg18325389 chr7:116450458 NA -0.2 -4.52 -0.38 1.42e-5 Hematocrit; TGCT cis rs6459788 0.605 rs887628 chr7:157237589 G/A cg03453431 chr7:157225567 NA -0.4 -5.8 -0.46 5.3e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs10193935 0.892 rs6744964 chr2:42441088 A/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9929218 0.551 rs1886697 chr16:68716179 T/C cg01251360 chr16:68772225 CDH1 -0.27 -4.92 -0.4 2.75e-6 Colorectal cancer; TGCT cis rs8038465 1.000 rs8038465 chr15:73978337 A/G cg15420318 chr15:73925796 NPTN -0.74 -6.98 -0.53 1.55e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6089829 0.925 rs4809270 chr20:61676709 C/A cg08564027 chr20:61660810 NA 0.37 6.0 0.47 2e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7296418 0.630 rs11057238 chr12:123767971 C/A cg00376283 chr12:123451042 ABCB9 0.66 5.64 0.45 1.09e-7 Platelet count; TGCT cis rs6860806 0.507 rs270606 chr5:131650867 A/G cg24060327 chr5:131705240 SLC22A5 -0.73 -7.77 -0.57 2.59e-12 Breast cancer; TGCT cis rs2637266 1.000 rs12260492 chr10:78365242 C/A cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs6438424 0.521 rs10934427 chr3:117721983 T/C cg15509235 chr3:117715573 NA 0.53 5.27 0.43 5.83e-7 Menarche (age at onset); TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg07157834 chr1:205819609 PM20D1 0.44 7.12 0.54 7.56e-11 Menarche (age at onset); TGCT cis rs1448094 0.717 rs7298614 chr12:86296513 C/T cg02569458 chr12:86230093 RASSF9 0.36 4.61 0.38 1e-5 Major depressive disorder; TGCT cis rs28595532 0.748 rs17594978 chr4:119336398 T/C cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs8179 0.542 rs3731326 chr7:92327026 A/G cg15732164 chr7:92237376 CDK6 -0.3 -5.17 -0.42 8.94e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT trans rs17685 0.753 rs7788763 chr7:75651665 T/C cg19862616 chr7:65841803 NCRNA00174 -0.51 -8.53 -0.61 4.32e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs8031584 0.678 rs8028173 chr15:31155749 A/G cg14829155 chr15:31115871 NA -0.36 -4.72 -0.39 6.14e-6 Huntington's disease progression; TGCT cis rs769267 0.929 rs34538000 chr19:19481379 G/T cg03709012 chr19:19516395 GATAD2A -0.79 -6.75 -0.52 4.97e-10 Tonsillectomy; TGCT cis rs11264213 0.591 rs684594 chr1:36489977 G/A cg27506609 chr1:36549197 TEKT2 -0.31 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT cis rs74233809 1.000 rs12411886 chr10:104685299 C/A cg05855489 chr10:104503620 C10orf26 0.75 4.47 0.37 1.72e-5 Birth weight; TGCT cis rs1355223 0.583 rs2941060 chr11:34879154 G/A cg11058730 chr11:34937778 PDHX;APIP 0.8 8.77 0.62 1.16e-14 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs2072499 0.750 rs909269 chr1:156192028 C/T cg24450063 chr1:156163899 SLC25A44 1.03 9.7 0.66 6.62e-17 Testicular germ cell tumor; TGCT cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs8050907 0.744 rs7191458 chr16:4511752 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs2153535 0.526 rs9406179 chr6:8538224 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs7666738 0.606 rs3846446 chr4:99099768 C/A cg05340658 chr4:99064831 C4orf37 0.42 4.49 0.37 1.62e-5 Colonoscopy-negative controls vs population controls; TGCT trans rs4332037 0.539 rs34809719 chr7:2028968 G/T cg10840412 chr1:235813424 GNG4 0.93 6.69 0.51 6.97e-10 Bipolar disorder; TGCT cis rs1348850 0.914 rs12616443 chr2:178315751 A/G cg22681709 chr2:178499509 PDE11A -0.37 -4.85 -0.4 3.66e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs10028773 0.515 rs9994651 chr4:120587803 C/T cg09307838 chr4:120376055 NA 0.56 5.33 0.43 4.39e-7 Educational attainment; TGCT cis rs6582630 0.502 rs4309219 chr12:38293584 A/G cg26384229 chr12:38710491 ALG10B 0.78 7.01 0.53 1.36e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs10876993 0.890 rs810204 chr12:58075733 T/C cg15848620 chr12:58087721 OS9 -0.72 -5.83 -0.46 4.52e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs6582630 0.537 rs1851124 chr12:38516404 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.68 0.57 4.16e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs4851254 0.660 rs60697219 chr2:100699507 G/A cg07810366 chr2:100720526 AFF3 -0.47 -4.92 -0.4 2.66e-6 Intelligence (multi-trait analysis); TGCT cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs4595586 0.505 rs12826314 chr12:39379435 A/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs17376456 0.569 rs10050364 chr5:93064127 T/C cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT cis rs6570726 0.935 rs368848 chr6:145855281 A/T cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs73001065 0.636 rs8182472 chr19:19539891 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.83 4.59 0.38 1.08e-5 LDL cholesterol; TGCT cis rs7681440 0.775 rs6848181 chr4:90807252 T/C cg14346243 chr4:90757452 SNCA -0.5 -4.75 -0.39 5.46e-6 Dementia with Lewy bodies; TGCT cis rs1113500 0.787 rs10881502 chr1:108641819 C/T cg22161131 chr1:109420278 GPSM2 -0.5 -4.64 -0.38 8.69e-6 Growth-regulated protein alpha levels; TGCT cis rs7017914 0.870 rs3098874 chr8:71934338 G/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs7264396 0.690 rs17093156 chr20:34438583 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs35306767 0.855 rs61830931 chr10:932497 T/C cg20503657 chr10:835505 NA 0.8 11.88 0.73 3.41e-22 Eosinophil percentage of granulocytes; TGCT cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg08392591 chr16:89556376 ANKRD11 0.55 5.06 0.41 1.49e-6 Multiple myeloma (IgH translocation); TGCT cis rs763121 0.853 rs4821811 chr22:39075145 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.47 0.56 1.24e-11 Menopause (age at onset); TGCT cis rs9581857 0.615 rs79793528 chr13:28007823 G/A cg22138327 chr13:27999177 GTF3A 0.8 5.52 0.44 1.9e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs3796352 0.881 rs11710394 chr3:53015839 A/G cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg24531977 chr5:56204891 C5orf35 -0.79 -7.18 -0.54 5.77e-11 Initial pursuit acceleration; TGCT trans rs4650994 0.544 rs4652301 chr1:178499799 T/C cg05059571 chr16:84539110 KIAA1609 -0.54 -11.12 -0.71 2.39e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg18252515 chr7:66147081 NA -1.14 -6.81 -0.52 3.76e-10 Diabetic kidney disease; TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg11494091 chr17:61959527 GH2 0.61 14.48 0.79 2.05e-28 Prudent dietary pattern; TGCT cis rs4788439 0.901 rs11864339 chr16:24993436 T/C cg07626409 chr16:25250191 ZKSCAN2 0.33 4.6 0.38 1.03e-5 Blood metabolite levels; TGCT cis rs28595532 0.920 rs114165587 chr4:119779525 C/T cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs12220898 0.749 rs4478905 chr10:50479539 G/A cg06072769 chr10:50146962 WDFY4 0.35 4.5 0.37 1.56e-5 Inflammatory biomarkers; TGCT cis rs2300747 0.872 rs6677309 chr1:117080166 A/C cg26677431 chr1:117075710 CD58 -0.22 -4.67 -0.39 7.55e-6 Primary biliary cholangitis;Multiple sclerosis; TGCT trans rs4332037 0.624 rs11766944 chr7:1888051 G/A cg25206134 chr2:45395956 NA 0.96 8.2 0.59 2.59e-13 Bipolar disorder; TGCT cis rs9653442 0.900 rs6740838 chr2:100813499 T/G cg22139774 chr2:100720529 AFF3 -0.39 -6.26 -0.49 5.75e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7119038 0.818 rs1048024 chr11:118618776 A/T cg19308663 chr11:118741387 NA 0.29 5.39 0.44 3.41e-7 Sjögren's syndrome; TGCT cis rs1348850 0.632 rs13008833 chr2:178514439 G/C cg22681709 chr2:178499509 PDE11A -0.51 -6.37 -0.5 3.35e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs950169 0.922 rs6603022 chr15:84830170 T/C cg11189052 chr15:85197271 WDR73 -0.81 -6.52 -0.51 1.61e-9 Schizophrenia; TGCT cis rs17345786 0.906 rs59359251 chr3:101146362 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs763121 0.813 rs4821807 chr22:39065582 A/G cg06022373 chr22:39101656 GTPBP1 0.78 7.56 0.56 7.78e-12 Menopause (age at onset); TGCT trans rs1814175 0.692 rs1851873 chr11:49937767 A/G cg15704280 chr7:45808275 SEPT13 -0.59 -6.82 -0.52 3.54e-10 Height; TGCT cis rs853679 0.546 rs200490 chr6:27796935 G/T cg10876282 chr6:28092338 ZSCAN16 0.76 4.47 0.37 1.73e-5 Depression; TGCT trans rs6089829 0.925 rs3746748 chr20:61667526 C/T cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.861 rs35581164 chr1:53271373 C/G cg01802117 chr1:53393560 SCP2 -0.43 -5.15 -0.42 9.84e-7 Monocyte count; TGCT cis rs9393692 0.645 rs9467703 chr6:26318903 A/G cg13736514 chr6:26305472 NA -0.46 -6.7 -0.52 6.47e-10 Educational attainment; TGCT cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6542838 0.611 rs7423519 chr2:99518319 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.65 -0.39 8.34e-6 Fear of minor pain; TGCT cis rs6430585 0.528 rs2278682 chr2:136743143 G/C cg07169764 chr2:136633963 MCM6 1.2 11.66 0.72 1.18e-21 Corneal structure; TGCT cis rs11711311 0.668 rs11718061 chr3:113341826 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.7 5.81 0.46 4.86e-8 IgG glycosylation; TGCT cis rs2404602 0.692 rs4360890 chr15:77173295 G/A cg26408565 chr15:76604113 ETFA -0.36 -4.52 -0.38 1.41e-5 Blood metabolite levels; TGCT cis rs682748 1.000 rs683580 chr5:17155359 G/A cg23987134 chr5:17158319 LOC285696 -0.23 -5.42 -0.44 2.93e-7 Hippocampal atrophy; TGCT cis rs9303401 0.659 rs2072316 chr17:56604813 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs10791323 0.559 rs10750548 chr11:133729469 A/G cg15485101 chr11:133734466 NA 0.42 5.26 0.43 6.25e-7 Childhood ear infection; TGCT cis rs7824557 0.527 rs57629785 chr8:11235150 C/A cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.97e-9 Retinal vascular caliber; TGCT cis rs28785552 0.897 rs34244888 chr19:53242228 T/A cg10871876 chr19:53194124 ZNF83 0.56 7.99 0.58 7.74e-13 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs877282 0.898 rs11253352 chr10:766598 C/A cg17470449 chr10:769945 NA 0.34 5.24 0.43 6.59e-7 Uric acid levels; TGCT cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs8111998 0.826 rs8108776 chr19:22765384 C/T cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs926938 0.527 rs360670 chr1:115482386 G/A cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs1372520 0.627 rs2583964 chr4:90727218 A/G cg14346243 chr4:90757452 SNCA -0.68 -5.64 -0.45 1.12e-7 Neuroticism; TGCT cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg06634786 chr22:41940651 POLR3H -0.86 -8.01 -0.58 7.16e-13 Vitiligo; TGCT cis rs7647973 0.925 rs4955423 chr3:49220448 G/A cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.79 -0.4 4.63e-6 Menarche (age at onset); TGCT cis rs9674544 0.757 rs2289636 chr17:47120776 T/C cg20966754 chr17:47091339 IGF2BP1 -0.4 -4.45 -0.37 1.89e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs13118159 0.801 rs7664474 chr4:1329116 T/A cg13395646 chr4:1353034 KIAA1530 -0.41 -4.6 -0.38 1.01e-5 Longevity; TGCT trans rs10506458 0.834 rs73127067 chr12:63390333 G/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.5 -0.61 5.08e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs910316 1.000 rs8003506 chr14:75586288 A/C cg23033748 chr14:75592666 NEK9 -0.26 -4.56 -0.38 1.22e-5 Height; TGCT cis rs72781680 0.799 rs17508218 chr2:23976536 C/T cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs6912958 1.000 rs9450701 chr6:88173167 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.6 -5.71 -0.46 8.03e-8 Monocyte percentage of white cells; TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg04025307 chr7:1156635 C7orf50 0.22 5.3 0.43 5.13e-7 Longevity;Endometriosis; TGCT cis rs2299587 0.554 rs13253029 chr8:17749622 C/T cg01800426 chr8:17659068 MTUS1 -0.55 -4.74 -0.39 5.65e-6 Economic and political preferences; TGCT cis rs12477438 0.765 rs10181344 chr2:99692829 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs6088590 1.000 rs2378256 chr20:33292127 G/C cg06115741 chr20:33292138 TP53INP2 0.67 5.77 0.46 5.93e-8 Coronary artery disease; TGCT cis rs7095607 0.538 rs2634708 chr10:69920013 C/A cg18986048 chr10:69913749 MYPN 0.61 5.85 0.46 4.16e-8 Lung function (FVC); TGCT cis rs8180040 0.967 rs807935 chr3:47321669 A/G cg27129171 chr3:47204927 SETD2 0.7 8.89 0.62 5.88e-15 Colorectal cancer; TGCT cis rs6977955 1.000 rs2893312 chr7:28170403 C/T cg23620719 chr7:28220237 JAZF1 -0.66 -5.01 -0.41 1.8e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs752010 0.619 rs10736421 chr1:42106230 G/A cg06885757 chr1:42089581 HIVEP3 0.29 5.02 0.41 1.72e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs17001868 0.568 rs909669 chr22:40742417 C/T cg07138101 chr22:40742427 ADSL 0.75 5.49 0.44 2.14e-7 Mammographic density (dense area); TGCT cis rs17221829 0.703 rs1962258 chr11:89380687 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs1215050 0.791 rs1585088 chr4:98675071 C/A cg05340658 chr4:99064831 C4orf37 -0.43 -5.19 -0.42 8.34e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13256369 1.000 rs4840352 chr8:8573508 A/G cg17143192 chr8:8559678 CLDN23 0.62 5.82 0.46 4.82e-8 Obesity-related traits; TGCT cis rs17270561 1.000 rs12200962 chr6:25828986 T/C cg17691542 chr6:26056736 HIST1H1C 0.78 4.78 0.39 4.87e-6 Iron status biomarkers; TGCT cis rs951366 0.870 rs3747973 chr1:205677148 A/G cg14893161 chr1:205819251 PM20D1 0.4 4.82 0.4 4.07e-6 Menarche (age at onset); TGCT cis rs586688 0.929 rs678092 chr1:201640266 G/A cg05779441 chr1:201574716 NA 0.29 4.8 0.4 4.54e-6 Obesity-related traits; TGCT cis rs13326165 0.715 rs11707864 chr3:52392877 G/A cg27565382 chr3:53032988 SFMBT1 0.36 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6901004 0.803 rs9387000 chr6:111459941 A/C cg15721981 chr6:111408429 SLC16A10 -0.53 -4.67 -0.39 7.84e-6 Blood metabolite levels; TGCT cis rs6593803 0.547 rs7528262 chr1:147248817 C/T cg17941330 chr1:147245494 GJA5 0.34 4.5 0.37 1.52e-5 Methotrexate-induced interstitial lung disease in rheumatoid arthritis; TGCT cis rs62103177 0.564 rs7228971 chr18:77738025 C/T cg07235805 chr18:78004237 PARD6G -0.51 -4.87 -0.4 3.38e-6 Opioid sensitivity; TGCT cis rs950169 0.541 rs10795 chr15:85177297 G/A cg12863693 chr15:85201151 NMB 0.46 5.56 0.45 1.6e-7 Schizophrenia; TGCT cis rs4242434 0.927 rs13271626 chr8:22467760 C/G cg21658235 chr8:22456391 C8orf58 0.43 4.5 0.37 1.54e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs1018836 0.828 rs4735236 chr8:91583909 A/G cg16814680 chr8:91681699 NA -0.72 -7.28 -0.55 3.32e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6095298 0.595 rs4810881 chr20:47437212 T/G cg12307787 chr20:48099359 KCNB1 0.43 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs7809950 0.648 rs114452520 chr7:107176780 C/T cg23024343 chr7:107201750 COG5 -0.35 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs1552244 1.000 rs7637888 chr3:10080722 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs6733011 0.508 rs4851173 chr2:99520608 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.44 -0.44 2.74e-7 Bipolar disorder; TGCT cis rs7249142 0.549 rs2283623 chr19:19283027 G/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.34 -4.61 -0.38 9.98e-6 IgG glycosylation; TGCT cis rs881375 0.678 rs1014530 chr9:123685092 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.47 5.19 0.42 8.48e-7 Rheumatoid arthritis; TGCT cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg00343986 chr7:65444356 GUSB -0.26 -6.14 -0.48 1.05e-8 Calcium levels; TGCT cis rs6087990 0.769 rs17123658 chr20:31390840 C/A cg13636640 chr20:31349939 DNMT3B 1.05 14.11 0.78 1.48e-27 Ulcerative colitis; TGCT cis rs9638182 0.623 rs71556715 chr7:72881807 C/T cg14087351 chr7:73037990 MLXIPL -0.57 -4.52 -0.38 1.4e-5 Triglycerides; TGCT cis rs7824557 0.843 rs2572418 chr8:11113089 G/A cg21775007 chr8:11205619 TDH -0.51 -4.63 -0.38 8.95e-6 Retinal vascular caliber; TGCT cis rs765787 0.530 rs11858988 chr15:45522114 T/C cg24006582 chr15:45444508 DUOX1 -0.26 -5.64 -0.45 1.12e-7 Uric acid levels; TGCT cis rs13256369 1.000 rs9329166 chr8:8576655 C/T cg17143192 chr8:8559678 CLDN23 0.59 5.9 0.47 3.27e-8 Obesity-related traits; TGCT trans rs2688608 0.725 rs2633314 chr10:75683590 C/T cg13918328 chr10:52500089 ASAH2B 0.68 6.93 0.53 1.99e-10 Inflammatory bowel disease; TGCT cis rs7681440 0.904 rs6816305 chr4:90772902 C/G cg14346243 chr4:90757452 SNCA -0.57 -5.5 -0.44 2.04e-7 Dementia with Lewy bodies; TGCT cis rs4841097 0.876 rs6601288 chr8:8943430 A/T cg06636001 chr8:8085503 FLJ10661 0.61 5.03 0.41 1.71e-6 Platelet distribution width; TGCT cis rs35883536 0.967 rs1577509 chr1:101089253 C/T cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.22e-5 Monocyte count; TGCT cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg01017244 chr2:74357527 NA 0.5 8.29 0.6 1.58e-13 Gestational age at birth (maternal effect); TGCT cis rs2299587 0.607 rs2237848 chr8:17874604 A/C cg01800426 chr8:17659068 MTUS1 -0.67 -5.95 -0.47 2.59e-8 Economic and political preferences; TGCT cis rs950169 0.922 rs4338765 chr15:84916836 G/T cg11189052 chr15:85197271 WDR73 0.83 6.67 0.51 7.71e-10 Schizophrenia; TGCT cis rs832540 0.618 rs41106 chr5:56145057 G/T cg12311346 chr5:56204834 C5orf35 -0.49 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs769267 0.965 rs8101938 chr19:19390497 G/A cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg01802117 chr1:53393560 SCP2 -0.48 -5.77 -0.46 6.09e-8 Monocyte count; TGCT cis rs9788682 0.948 rs28498264 chr15:78837673 C/T cg06917634 chr15:78832804 PSMA4 -0.69 -4.71 -0.39 6.49e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs763014 0.865 rs2018789 chr16:632051 T/C cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs17826219 0.561 rs11655876 chr17:29017150 G/A cg13385521 chr17:29058706 SUZ12P 0.74 4.59 0.38 1.07e-5 Body mass index; TGCT cis rs10191773 0.589 rs72833410 chr2:113054119 G/A cg07905836 chr2:113190072 RGPD8;RGPD5 0.47 5.03 0.41 1.67e-6 Yeast infection; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg00024416 chr22:24240387 NA -0.27 -5.3 -0.43 5.03e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2072499 0.966 rs2853641 chr1:156181770 A/G cg06970220 chr1:156163860 SLC25A44 0.66 5.79 0.46 5.4e-8 Testicular germ cell tumor; TGCT cis rs2204008 0.837 rs11495548 chr12:38076756 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.72 0.57 3.39e-12 Bladder cancer; TGCT cis rs4851254 0.961 rs6713524 chr2:100747357 A/G cg23118464 chr2:100721844 AFF3 0.71 5.28 0.43 5.62e-7 Intelligence (multi-trait analysis); TGCT cis rs8180040 0.966 rs7651762 chr3:47470484 G/A cg27129171 chr3:47204927 SETD2 -0.65 -7.56 -0.56 7.97e-12 Colorectal cancer; TGCT cis rs9611565 0.559 rs7290991 chr22:41964361 C/G cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs5769707 0.749 rs7286706 chr22:50058346 G/C cg20744362 chr22:50050164 C22orf34 0.29 4.69 0.39 7.19e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10791097 0.694 rs1893017 chr11:130756253 C/T cg12179176 chr11:130786555 SNX19 0.83 9.92 0.67 1.94e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1372520 1.000 rs1372520 chr4:90757505 T/C cg01966878 chr4:90757139 SNCA -0.31 -4.74 -0.39 5.73e-6 Neuroticism; TGCT cis rs2997447 0.655 rs12094933 chr1:26374779 T/C cg19633962 chr1:26362018 EXTL1 -0.66 -4.81 -0.4 4.33e-6 QRS complex (12-leadsum); TGCT cis rs6669919 0.647 rs1578838 chr1:211671118 T/G cg26515805 chr1:211431828 RCOR3 -0.45 -4.56 -0.38 1.2e-5 Intelligence (multi-trait analysis); TGCT cis rs7017914 0.967 rs62508819 chr8:71718106 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs853679 0.550 rs34477097 chr6:28197186 C/T cg12963246 chr6:28129442 ZNF389 0.45 4.44 0.37 1.96e-5 Depression; TGCT cis rs259282 0.583 rs12981373 chr19:33108189 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.59 5.29 0.43 5.27e-7 Schizophrenia; TGCT cis rs7085104 0.700 rs7096183 chr10:104609466 T/C cg05855489 chr10:104503620 C10orf26 0.51 4.54 0.38 1.34e-5 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7172809 0.599 rs12324795 chr15:77739786 T/C cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs6671200 0.688 rs4950024 chr1:95713499 A/G cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs6674176 0.628 rs4660758 chr1:44424879 A/C cg12908607 chr1:44402522 ARTN -0.66 -7.71 -0.57 3.51e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs3806843 0.576 rs246049 chr5:140327590 T/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs35306767 0.714 rs17293608 chr10:1056252 C/T cg20503657 chr10:835505 NA 0.58 6.68 0.51 7.2e-10 Eosinophil percentage of granulocytes; TGCT cis rs1150668 0.830 rs213240 chr6:28315875 T/C cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.57 -0.38 1.14e-5 Pubertal anthropometrics; TGCT cis rs950776 0.518 rs12906951 chr15:78825562 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs524281 0.861 rs10750778 chr11:65948648 T/C cg00563793 chr11:65837595 PACS1 0.57 4.97 0.41 2.13e-6 Electroencephalogram traits; TGCT cis rs11167764 1.000 rs13354528 chr5:141476769 C/T cg08523384 chr5:141488047 NDFIP1 -0.23 -4.7 -0.39 6.78e-6 Crohn's disease; TGCT cis rs67133203 0.607 rs706801 chr12:51366092 A/G cg01517968 chr12:52348879 ACVR1B 0.35 4.52 0.38 1.44e-5 Urinary tract infection frequency; TGCT cis rs7829975 0.846 rs6601724 chr8:8544872 C/T cg06636001 chr8:8085503 FLJ10661 -0.61 -5.26 -0.43 6.15e-7 Mood instability; TGCT cis rs2463822 1.000 rs2463821 chr11:62111662 T/C cg06239285 chr11:62104954 ASRGL1 0.89 5.91 0.47 3.04e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs3020333 0.703 rs862346 chr6:152016369 A/T cg22157087 chr6:152012887 ESR1 0.22 5.46 0.44 2.54e-7 Total body bone mineral density; TGCT cis rs9467711 0.606 rs9379873 chr6:26402717 T/C cg16898833 chr6:26189333 HIST1H4D 1.15 5.55 0.45 1.62e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6809651 0.524 rs1356291 chr3:185824644 C/T cg00760338 chr3:185826511 ETV5 0.78 6.52 0.51 1.56e-9 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs13242816 1.000 rs36011826 chr7:116118336 G/A cg02799643 chr7:116139180 CAV2 -0.49 -5.61 -0.45 1.27e-7 P wave duration; TGCT cis rs7267979 0.780 rs6050679 chr20:25537827 A/T cg14121845 chr20:25566513 NINL 0.47 4.93 0.4 2.6e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28735056 0.967 rs498541 chr18:77589655 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.53 -0.44 1.84e-7 Schizophrenia; TGCT cis rs7226408 1.000 rs72883551 chr18:34362836 C/T cg06757138 chr18:34340585 FHOD3 0.28 4.81 0.4 4.35e-6 Obesity-related traits; TGCT cis rs7208859 0.673 rs2433 chr17:29226228 T/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3780378 0.967 rs7039518 chr9:5046881 T/C cg02405213 chr9:5042618 JAK2 -0.6 -7.68 -0.57 4.04e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9322193 0.923 rs9968911 chr6:149978555 A/T cg13206674 chr6:150067644 NUP43 0.51 4.47 0.37 1.75e-5 Lung cancer; TGCT cis rs916888 0.773 rs199535 chr17:44822662 A/G cg17911788 chr17:44343683 NA -0.65 -6.93 -0.53 2.02e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs629535 0.862 rs598548 chr8:70032438 C/T cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs8077889 0.672 rs2074143 chr17:41856622 A/G cg26893861 chr17:41843967 DUSP3 1.14 20.46 0.88 1.46e-41 Triglycerides; TGCT cis rs10540 1.000 rs61876342 chr11:496193 T/G cg03352830 chr11:487213 PTDSS2 0.26 4.55 0.38 1.27e-5 Body mass index; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs6121246 0.821 rs7265413 chr20:30317923 G/A cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs17001868 0.614 rs5995849 chr22:40777072 C/G cg07138101 chr22:40742427 ADSL -0.76 -5.91 -0.47 3.07e-8 Mammographic density (dense area); TGCT cis rs2702888 0.512 rs2738153 chr8:6751900 T/G cg26795848 chr8:6756730 NA -0.32 -6.55 -0.51 1.41e-9 Blood pressure; TGCT cis rs12681287 0.517 rs34596274 chr8:87517679 C/T cg27223183 chr8:87520930 FAM82B -0.96 -7.08 -0.54 9.31e-11 Caudate activity during reward; TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg07157834 chr1:205819609 PM20D1 0.45 6.94 0.53 1.96e-10 Menarche (age at onset); TGCT cis rs1372520 0.684 rs1442144 chr4:90736113 T/C cg20003494 chr4:90757398 SNCA -0.65 -5.2 -0.42 8.15e-7 Neuroticism; TGCT cis rs2013441 1.000 rs2703821 chr17:20121526 C/T cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs208520 1.000 rs72884025 chr6:66994185 T/C cg07460842 chr6:66804631 NA 0.79 6.85 0.52 3.05e-10 Exhaled nitric oxide output; TGCT cis rs9291683 0.588 rs3796842 chr4:9995851 A/T cg00071950 chr4:10020882 SLC2A9 0.73 8.9 0.62 5.69e-15 Bone mineral density; TGCT cis rs7584330 0.554 rs77956735 chr2:238399130 C/T cg14458575 chr2:238380390 NA 0.59 5.08 0.42 1.34e-6 Prostate cancer; TGCT cis rs4819052 0.807 rs7283915 chr21:46671288 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9303542 0.559 rs1042822 chr17:46620095 G/T cg25032089 chr17:46643351 HOXB3 0.56 5.27 0.43 5.97e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6688613 1.000 rs6699520 chr1:166955405 G/C cg07049167 chr1:166818506 POGK 0.21 4.52 0.38 1.43e-5 Refractive astigmatism; TGCT cis rs939658 1.000 rs8033963 chr15:79455350 C/T cg17916960 chr15:79447300 NA 0.54 8.64 0.61 2.42e-14 Refractive error; TGCT cis rs8017423 0.933 rs7150378 chr14:90724566 G/A cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs7584330 0.868 rs58057291 chr2:238395479 T/A cg08992911 chr2:238395768 MLPH 0.63 4.61 0.38 9.83e-6 Prostate cancer; TGCT cis rs2050392 0.624 rs303435 chr10:30731491 T/C cg18806716 chr10:30721971 MAP3K8 -0.69 -9.45 -0.65 2.71e-16 Inflammatory bowel disease; TGCT cis rs10461617 0.541 rs832575 chr5:56161787 C/T cg18230493 chr5:56204884 C5orf35 -0.72 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs4689388 0.581 rs11727100 chr4:6281458 A/C cg25554036 chr4:6271136 WFS1 0.56 6.58 0.51 1.21e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9640161 0.742 rs2159235 chr7:150017228 T/C cg10018233 chr7:150070692 REPIN1 0.33 4.68 0.39 7.25e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs933688 1.000 rs61612071 chr5:90741470 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.25 0.6 1.91e-13 Smoking behavior; TGCT cis rs2361718 0.568 rs1042397 chr17:78092063 G/A cg09238746 chr17:78121135 EIF4A3 -0.66 -5.88 -0.47 3.48e-8 Yeast infection; TGCT cis rs9372498 0.536 rs9489395 chr6:118758884 T/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs11030122 0.733 rs10835331 chr11:3957365 C/T cg18678763 chr11:4115507 RRM1 -0.48 -5.99 -0.47 2.15e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs1056107 0.931 rs2274519 chr9:114997288 C/T cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg10295955 chr4:187884368 NA -0.99 -15.24 -0.81 3.38e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs3008870 1.000 rs2985795 chr1:67426223 A/G cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs8013055 0.846 rs12893999 chr14:105970842 C/G cg19700328 chr14:106028568 NA -0.53 -5.87 -0.47 3.76e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs17102884 0.506 rs10873274 chr14:75407372 G/T cg08847533 chr14:75593920 NEK9 -0.61 -5.22 -0.42 7.28e-7 Neuroticism; TGCT cis rs7267979 0.934 rs2500399 chr20:25354694 T/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10089 0.951 rs56066100 chr5:127460571 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs11578119 0.933 rs1591147 chr1:170445224 T/C cg09767346 chr1:170501363 GORAB -0.72 -5.74 -0.46 6.97e-8 Male-pattern baldness; TGCT cis rs904251 0.772 rs756202 chr6:37460350 C/A cg08126542 chr6:37504118 NA -0.39 -4.6 -0.38 1.04e-5 Cognitive performance; TGCT cis rs2204008 0.774 rs11616004 chr12:38278822 G/A cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs854765 0.562 rs2955381 chr17:17945500 G/C cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs9467773 1.000 rs9461271 chr6:26554968 G/A cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT trans rs7618501 0.602 rs2526743 chr3:50115245 G/A cg21659725 chr3:3221576 CRBN -0.73 -8.48 -0.61 5.64e-14 Intelligence (multi-trait analysis); TGCT cis rs4372836 0.729 rs11127190 chr2:29043212 G/C cg09522027 chr2:28974177 PPP1CB 0.66 6.76 0.52 4.88e-10 Body mass index; TGCT cis rs1023500 0.551 rs4822076 chr22:42364057 C/T cg15557168 chr22:42548783 NA -0.2 -4.55 -0.38 1.29e-5 Schizophrenia; TGCT cis rs3793683 0.825 rs3793674 chr10:134555773 C/T cg27286337 chr10:134555280 INPP5A -0.48 -7.48 -0.56 1.16e-11 Migraine; TGCT cis rs7772486 0.875 rs6930975 chr6:146387111 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.86 0.4 3.48e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1153858 1.000 rs4395020 chr15:45652889 A/C cg14582100 chr15:45693742 SPATA5L1 0.51 5.99 0.47 2.12e-8 Homoarginine levels; TGCT cis rs78456975 0.527 rs4073862 chr2:1563433 A/G cg01028140 chr2:1542097 TPO -0.33 -5.14 -0.42 1.02e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs4851266 0.833 rs11685491 chr2:100858122 A/G cg07810366 chr2:100720526 AFF3 -0.36 -5.21 -0.42 7.59e-7 Educational attainment; TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg14159672 chr1:205819179 PM20D1 0.61 7.43 0.55 1.57e-11 Menarche (age at onset); TGCT cis rs12136530 0.774 rs12563442 chr1:19786695 T/C cg18923740 chr1:19971790 NBL1 0.38 4.68 0.39 7.51e-6 Lead levels in blood; TGCT cis rs7567389 0.600 rs72845979 chr2:128095754 C/A cg09760422 chr2:128146352 NA 0.39 5.18 0.42 8.76e-7 Self-rated health; TGCT cis rs4566357 0.615 rs3769642 chr2:227917323 T/C cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs6840360 0.509 rs62327273 chr4:152547594 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs6456156 0.692 rs9457270 chr6:167512928 A/G cg07741184 chr6:167504864 NA 0.3 5.95 0.47 2.54e-8 Primary biliary cholangitis; TGCT cis rs1008375 1.000 rs11727312 chr4:17669185 C/T cg16339924 chr4:17578868 LAP3 0.57 4.75 0.39 5.43e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs992157 0.866 rs2292554 chr2:219146868 T/C cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg18402987 chr7:1209562 NA 0.91 7.67 0.57 4.43e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2295359 1.000 rs4655683 chr1:67611613 C/T cg03340356 chr1:67600835 NA 0.37 4.6 0.38 1.03e-5 Psoriasis; TGCT cis rs10782582 0.586 rs1856791 chr1:76308942 C/T cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs2458413 0.543 rs2514658 chr8:105337871 G/A cg23108931 chr8:105342351 NA -0.35 -6.15 -0.48 9.76e-9 Paget's disease; TGCT cis rs10114408 0.959 rs10761297 chr9:96647433 A/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs597539 0.617 rs686348 chr11:68636996 A/G cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs77457752 0.532 rs77481510 chr9:13902347 G/A cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.04e-10 Breast cancer; TGCT cis rs9814567 1.000 rs4535272 chr3:134299916 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.91 8.45 0.6 6.55e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs303386 0.501 rs6698436 chr1:99588903 A/G cg03593336 chr1:99471295 LPPR5 -0.25 -5.06 -0.41 1.49e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors);Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin); TGCT cis rs80282103 0.618 rs11250252 chr10:1124939 G/C cg08668510 chr10:1095578 IDI1 1.09 5.31 0.43 4.98e-7 Glomerular filtration rate (creatinine); TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg22764044 chr5:178986830 RUFY1 0.52 6.1 0.48 1.22e-8 Lung cancer; TGCT cis rs1580019 0.539 rs11769109 chr7:32571352 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.95 0.41 2.34e-6 Cognitive ability; TGCT cis rs4665809 1.000 rs4665823 chr2:26312723 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs11031096 0.678 rs970329 chr11:4189803 G/T cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs8084125 0.832 rs62105178 chr18:74950635 C/T cg07390210 chr18:74961196 GALR1 0.37 4.51 0.38 1.49e-5 Obesity-related traits; TGCT cis rs75059851 0.756 rs11223656 chr11:133842973 T/A cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs2239785 0.958 rs136160 chr22:36657119 C/G cg15716373 chr22:36655542 APOL1 -0.42 -4.84 -0.4 3.79e-6 Glomerulosclerosis; TGCT trans rs7618501 0.635 rs7635002 chr3:49989155 T/G cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.8e-16 Intelligence (multi-trait analysis); TGCT cis rs10242455 0.702 rs917152 chr7:99004497 T/C cg13560068 chr7:99070416 ZNF789 1.06 4.5 0.37 1.56e-5 Blood metabolite levels; TGCT cis rs9291683 0.935 rs1860911 chr4:10275057 C/T cg11266682 chr4:10021025 SLC2A9 0.45 5.41 0.44 3.13e-7 Bone mineral density; TGCT cis rs7552404 0.924 rs114752222 chr1:76180878 C/T cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11098499 0.697 rs28655325 chr4:120372999 A/G cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7178572 0.568 rs8030074 chr15:77654232 C/T cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs13102973 0.965 rs4864244 chr4:135866959 A/G cg14419869 chr4:135874104 NA 0.27 4.85 0.4 3.62e-6 Subjective well-being; TGCT cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7824557 0.836 rs1435278 chr8:11123029 G/T cg21775007 chr8:11205619 TDH -0.59 -5.7 -0.46 8.28e-8 Retinal vascular caliber; TGCT cis rs7552404 0.924 rs1146581 chr1:76213024 T/G cg22875332 chr1:76189707 ACADM 0.72 8.9 0.62 5.76e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2013441 1.000 rs3850781 chr17:20181939 T/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs829883 0.664 rs829876 chr12:98842138 A/G cg25150519 chr12:98850993 NA 0.62 7.36 0.55 2.2e-11 Colorectal adenoma (advanced); TGCT cis rs907683 0.584 rs12991025 chr2:220284779 C/T cg15015639 chr2:220282977 DES 0.4 5.04 0.41 1.6e-6 Resting heart rate; TGCT cis rs2688608 0.587 rs2894040 chr10:75478159 A/C cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs13424612 0.860 rs34277046 chr2:240897331 G/A cg26363272 chr2:240904871 NDUFA10 0.3 5.13 0.42 1.07e-6 Odorant perception (isobutyraldehyde); TGCT cis rs10782582 0.586 rs12130324 chr1:76370012 A/G cg03433033 chr1:76189801 ACADM -0.5 -4.91 -0.4 2.81e-6 Daytime sleep phenotypes; TGCT cis rs11190604 1.000 rs2489047 chr10:102347028 A/G cg16342193 chr10:102329863 NA -0.4 -5.12 -0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3087591 1.000 rs2905800 chr17:29531980 A/G cg24425628 chr17:29625626 OMG;NF1 0.48 7.29 0.55 3.25e-11 Hip circumference; TGCT cis rs28595532 0.841 rs116521340 chr4:119757415 C/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs35883536 0.647 rs12023028 chr1:101042717 C/T cg10298815 chr1:101004474 GPR88 -0.25 -4.73 -0.39 6.03e-6 Monocyte count; TGCT cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg07507251 chr3:52567010 NT5DC2 -0.49 -6.82 -0.52 3.62e-10 Bipolar disorder; TGCT cis rs10876993 0.784 rs10083154 chr12:58020933 G/A cg15848620 chr12:58087721 OS9 0.71 5.28 0.43 5.5e-7 Celiac disease or Rheumatoid arthritis; TGCT cis rs4319547 0.619 rs7973869 chr12:122874284 G/C cg05707623 chr12:122985044 ZCCHC8 -0.62 -4.87 -0.4 3.32e-6 Body mass index; TGCT cis rs72781680 0.898 rs72796171 chr2:23942667 G/C cg08917208 chr2:24149416 ATAD2B 0.77 4.71 0.39 6.52e-6 Lymphocyte counts; TGCT cis rs4722166 0.630 rs7808457 chr7:22798265 A/T cg13104385 chr7:22767384 IL6 -0.19 -4.48 -0.37 1.66e-5 Lung cancer; TGCT cis rs2239547 0.522 rs2710345 chr3:52976075 T/C cg11645453 chr3:52864694 ITIH4 -0.32 -5.23 -0.42 7.06e-7 Schizophrenia; TGCT cis rs7178572 0.633 rs11855188 chr15:77840714 A/G cg22256960 chr15:77711686 NA -0.77 -7.15 -0.54 6.45e-11 Type 2 diabetes; TGCT cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT trans rs1005277 0.579 rs2749616 chr10:38510993 A/T cg27523141 chr10:43048294 ZNF37B 0.71 8.26 0.6 1.84e-13 Extrinsic epigenetic age acceleration; TGCT cis rs11107903 1.000 rs11107896 chr12:95502303 G/A cg10621809 chr12:95840313 NA 0.7 4.61 0.38 9.89e-6 Coronary artery disease; TGCT cis rs6740322 0.895 rs6760797 chr2:43559612 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.58 -0.51 1.17e-9 Coronary artery disease; TGCT cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg05025164 chr4:1340916 KIAA1530 0.79 6.92 0.53 2.17e-10 Longevity; TGCT cis rs11648796 0.757 rs3809665 chr16:764520 G/C cg27144592 chr16:783916 NARFL 0.37 5.15 0.42 9.94e-7 Height; TGCT cis rs10490913 1.000 rs7916161 chr10:120145648 A/G cg23160142 chr10:120154512 NA -0.3 -4.74 -0.39 5.71e-6 Cancer; TGCT cis rs7731657 0.537 rs7725020 chr5:130285115 C/G cg08523029 chr5:130500466 HINT1 0.58 4.84 0.4 3.8e-6 Fasting plasma glucose; TGCT cis rs56399783 0.901 rs6964740 chr7:2819656 C/G cg19731401 chr7:2775893 GNA12 0.36 5.07 0.41 1.41e-6 Childhood ear infection; TGCT cis rs6733011 0.578 rs12468024 chr2:99495980 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.5 -4.79 -0.4 4.63e-6 Bipolar disorder; TGCT cis rs12477438 0.822 rs6727170 chr2:99588042 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.64 -4.93 -0.41 2.53e-6 Chronic sinus infection; TGCT cis rs4819052 0.851 rs2236445 chr21:46678453 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.8 6.98 0.53 1.55e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg10465839 chr16:1584050 IFT140;TMEM204 -0.31 -5.04 -0.41 1.61e-6 Coronary artery disease; TGCT cis rs28595532 0.920 rs10001115 chr4:119781867 A/C cg14228332 chr4:119757509 SEC24D 1.19 6.66 0.51 8.07e-10 Cannabis dependence symptom count; TGCT cis rs60843830 1.000 rs55753056 chr2:243929 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.74 7.5 0.56 1.05e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2637266 0.967 rs7477607 chr10:78358768 G/T cg18941641 chr10:78392320 NA 0.39 4.87 0.4 3.29e-6 Pulmonary function; TGCT cis rs2721195 0.874 rs2721173 chr8:145744429 C/T cg11211951 chr8:145729740 GPT 0.27 6.56 0.51 1.34e-9 Age at first birth; TGCT cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9302065 0.565 rs2993586 chr13:95962578 T/C cg26751094 chr13:95954534 ABCC4 -0.4 -6.74 -0.52 5.33e-10 Blood metabolite levels; TGCT cis rs28595532 0.920 rs56027489 chr4:119780882 A/G cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs259282 0.605 rs55687317 chr19:33109191 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.34 0.43 4.25e-7 Schizophrenia; TGCT cis rs67478160 0.643 rs12891175 chr14:104274166 T/C cg26031613 chr14:104095156 KLC1 -0.64 -6.57 -0.51 1.23e-9 Schizophrenia; TGCT cis rs4383453 0.539 rs12631960 chr3:123097568 A/G cg04890266 chr3:123102914 ADCY5 -0.5 -8.34 -0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs7523273 0.546 rs2796261 chr1:207888760 C/T cg22525895 chr1:207977042 MIR29B2 -0.35 -5.72 -0.46 7.49e-8 Schizophrenia; TGCT cis rs9486719 1.000 rs11152969 chr6:96908712 A/C cg18709589 chr6:96969512 KIAA0776 -0.68 -5.05 -0.41 1.55e-6 Migraine;Coronary artery disease; TGCT trans rs1005277 0.579 rs1780145 chr10:38537070 A/G cg17830980 chr10:43048298 ZNF37B -0.83 -10.39 -0.68 1.4e-18 Extrinsic epigenetic age acceleration; TGCT trans rs7613875 0.578 rs4688753 chr3:50074773 A/G cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT cis rs7666738 0.687 rs6839454 chr4:99073914 T/C cg05340658 chr4:99064831 C4orf37 0.51 5.62 0.45 1.18e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs829883 0.738 rs249854 chr12:98862772 G/A cg25150519 chr12:98850993 NA 0.63 7.57 0.56 7.21e-12 Colorectal adenoma (advanced); TGCT cis rs12142240 0.659 rs72677591 chr1:46818219 T/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs10746514 0.833 rs2356925 chr1:232261769 G/A cg09506761 chr1:232265262 NA -0.49 -4.99 -0.41 2.01e-6 Response to statin therapy; TGCT cis rs28595532 0.920 rs114333298 chr4:119765305 C/A cg21605333 chr4:119757512 SEC24D 1.57 8.38 0.6 9.59e-14 Cannabis dependence symptom count; TGCT cis rs936229 0.690 rs2472299 chr15:75033400 C/T cg10253484 chr15:75165896 SCAMP2 0.56 4.79 0.4 4.69e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs1729951 0.575 rs168635 chr3:136699078 A/G cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs13326165 0.760 rs67834575 chr3:52411929 T/A cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs514406 0.800 rs4926930 chr1:53217335 A/G cg08736216 chr1:53307985 ZYG11A 0.25 4.77 0.39 4.98e-6 Monocyte count; TGCT cis rs1729951 0.546 rs12054408 chr3:136677645 T/C cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs7666738 0.606 rs28481322 chr4:99086638 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.67 0.39 7.61e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs629535 0.735 rs525610 chr8:70074535 A/G cg21567404 chr3:27674614 NA 0.57 9.09 0.63 1.94e-15 Dupuytren's disease; TGCT cis rs4654899 0.758 rs3820326 chr1:21277141 G/A cg01072550 chr1:21505969 NA -0.56 -9.15 -0.63 1.47e-15 Superior frontal gyrus grey matter volume; TGCT cis rs7647973 0.710 rs11130207 chr3:49611666 T/G cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs9467773 1.000 rs9467796 chr6:26568411 A/G cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.900 rs4698625 chr4:17599500 G/T cg10189774 chr4:17578691 LAP3 0.65 5.28 0.43 5.54e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.830 rs1365458 chr4:98950961 C/T cg05340658 chr4:99064831 C4orf37 0.55 6.13 0.48 1.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9296092 0.500 rs9469504 chr6:33527243 G/A cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg17554472 chr22:41940697 POLR3H 0.48 4.95 0.41 2.39e-6 Vitiligo; TGCT cis rs7216064 1.000 rs4318247 chr17:65882172 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6840360 0.593 rs4696287 chr4:152606723 C/T cg17479576 chr4:152424074 FAM160A1 -0.61 -6.29 -0.49 4.86e-9 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.811 rs60708039 chr17:46999373 C/G cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs17253792 0.822 rs10136155 chr14:56049129 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3749237 0.576 rs3877784 chr3:49539417 C/T cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.29e-9 Cognitive function; TGCT cis rs28595532 0.920 rs116094766 chr4:119729291 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs9329289 0.510 rs35854428 chr10:2554280 T/C cg07014206 chr10:2547000 NA -0.28 -4.64 -0.38 8.6e-6 Age-related hearing impairment; TGCT cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs1372520 0.684 rs356188 chr4:90691537 T/C cg14346243 chr4:90757452 SNCA 0.62 5.29 0.43 5.26e-7 Neuroticism; TGCT cis rs35306767 0.761 rs11253558 chr10:1043983 T/C cg26597838 chr10:835615 NA 0.6 6.63 0.51 9.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg07061783 chr6:25882402 NA 0.64 6.7 0.52 6.57e-10 Blood metabolite levels; TGCT cis rs9443645 0.869 rs10943585 chr6:79502409 G/C cg09184832 chr6:79620586 NA -0.45 -4.82 -0.4 4.16e-6 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.774 rs3910796 chr12:38230660 G/T cg26384229 chr12:38710491 ALG10B 0.85 7.52 0.56 9.65e-12 Bladder cancer; TGCT cis rs2243480 1.000 rs186378 chr7:65582058 A/C cg18252515 chr7:66147081 NA -1.24 -8.1 -0.59 4.35e-13 Diabetic kidney disease; TGCT cis rs2885056 0.783 rs12459941 chr19:10666112 A/G cg04833646 chr19:10679720 CDKN2D -0.95 -9.26 -0.64 7.75e-16 Red cell distribution width; TGCT cis rs1568889 1.000 rs16917687 chr11:28062614 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs10858047 0.883 rs79867 chr1:115165110 A/C cg12756093 chr1:115239321 AMPD1 -0.48 -4.68 -0.39 7.27e-6 Autism; TGCT cis rs9926296 0.744 rs164748 chr16:89708292 C/G cg01097406 chr16:89675127 NA 0.35 6.31 0.49 4.55e-9 Vitiligo; TGCT cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg10802521 chr3:52805072 NEK4 -0.65 -7.82 -0.57 1.98e-12 Electroencephalogram traits; TGCT cis rs453301 0.686 rs28665409 chr8:8869277 G/A cg06636001 chr8:8085503 FLJ10661 -0.68 -5.62 -0.45 1.21e-7 Joint mobility (Beighton score); TGCT cis rs2905347 0.895 rs2905308 chr7:22648194 G/A cg26061582 chr7:22766209 IL6 -0.4 -4.53 -0.38 1.38e-5 Major depression and alcohol dependence; TGCT cis rs4727027 0.866 rs12666477 chr7:148812322 A/G cg23583168 chr7:148888333 NA -0.72 -9.16 -0.64 1.34e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6951245 0.554 rs78999139 chr7:1138525 G/A cg09177884 chr7:1199841 ZFAND2A -0.72 -5.71 -0.46 7.86e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs854765 0.533 rs2955354 chr17:17948716 G/C cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs3764400 0.567 rs16953941 chr17:46296204 C/A cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs34245846 0.769 rs12089941 chr1:154827520 T/C cg06418219 chr1:154948305 SHC1;CKS1B 0.73 5.83 0.46 4.53e-8 Atrial fibrillation; TGCT cis rs7246657 0.722 rs28512414 chr19:38056574 T/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs3096299 0.869 rs748941 chr16:89440754 T/A cg06640241 chr16:89574553 SPG7 0.64 5.88 0.47 3.55e-8 Multiple myeloma (IgH translocation); TGCT cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg08280861 chr8:58055591 NA 0.52 5.78 0.46 5.78e-8 Developmental language disorder (linguistic errors); TGCT cis rs12620999 0.555 rs10199274 chr2:238111864 G/C cg23555395 chr2:238036564 NA -0.29 -4.94 -0.41 2.43e-6 Systemic lupus erythematosus; TGCT cis rs7949030 0.596 rs11231137 chr11:62315699 G/A cg22862634 chr11:62369728 EML3;MTA2 0.62 6.25 0.49 5.9e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7226408 0.857 rs59065432 chr18:34419345 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.83 0.4 4.02e-6 Obesity-related traits; TGCT cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs6963495 0.818 rs6977748 chr7:105167462 T/G cg20976433 chr7:105162600 PUS7 -0.62 -4.45 -0.37 1.88e-5 Bipolar disorder (body mass index interaction); TGCT cis rs11098499 0.820 rs6829903 chr4:120506884 C/T cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs11098499 0.605 rs6833140 chr4:120266822 G/A cg09307838 chr4:120376055 NA 0.56 5.49 0.44 2.18e-7 Corneal astigmatism; TGCT cis rs854572 1.000 rs854572 chr7:94954696 C/G cg17330251 chr7:94953956 PON1 -0.61 -8.09 -0.59 4.58e-13 Paraoxonase activity; TGCT cis rs7267979 1.000 rs1047171 chr20:25428786 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs853679 0.517 rs9357061 chr6:28051772 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs4455778 0.727 rs10279104 chr7:49071187 A/G cg26309511 chr7:48887640 NA 0.47 5.33 0.43 4.56e-7 Lung cancer in never smokers; TGCT cis rs12478296 1.000 rs56323081 chr2:243040807 A/G cg06360820 chr2:242988706 NA -0.81 -5.39 -0.44 3.36e-7 Obesity-related traits; TGCT cis rs3924048 0.559 rs4075304 chr1:12626803 C/T cg00291366 chr1:12616550 NA 0.32 5.03 0.41 1.66e-6 Optic cup area; TGCT cis rs568617 0.953 rs658938 chr11:65651830 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.57 -5.22 -0.42 7.39e-7 Crohn's disease; TGCT cis rs7752195 0.643 rs75672316 chr6:25250050 A/G cg16898833 chr6:26189333 HIST1H4D 1.17 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6964587 1.000 rs6974607 chr7:91750116 G/A cg17063962 chr7:91808500 NA 0.88 9.3 0.64 6.22e-16 Breast cancer; TGCT cis rs7027203 0.576 rs7851269 chr9:96540530 C/T cg13679303 chr9:96623674 NA 0.53 7.64 0.57 5.06e-12 DNA methylation (variation); TGCT cis rs1018836 0.828 rs12547016 chr8:91563847 T/C cg16814680 chr8:91681699 NA -0.75 -7.85 -0.58 1.71e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg11941060 chr3:133502564 NA -0.31 -6.62 -0.51 9.53e-10 Iron status biomarkers; TGCT cis rs7959452 0.590 rs56054057 chr12:69775972 C/T cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs1997103 0.954 rs6593222 chr7:55372932 A/C cg17469321 chr7:55412551 NA 0.64 6.6 0.51 1.1e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs3796352 1.000 rs11707575 chr3:53113762 G/T cg15956490 chr3:53032818 SFMBT1 0.48 5.39 0.44 3.4e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7809950 1.000 rs4730245 chr7:107087294 C/T cg23024343 chr7:107201750 COG5 -0.35 -5.48 -0.44 2.28e-7 Coronary artery disease; TGCT cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg18252515 chr7:66147081 NA -0.9 -6.4 -0.5 2.83e-9 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs78803505 chr7:65382572 A/T cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg15242686 chr22:24348715 GSTTP1 -0.5 -7.53 -0.56 9.28e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3617 0.539 rs4687689 chr3:52948674 A/C cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.88 0.4 3.18e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6570726 0.967 rs441364 chr6:145853662 G/C cg23711669 chr6:146136114 FBXO30 0.7 6.52 0.51 1.63e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs11696501 0.688 rs4810461 chr20:44278445 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 8.98e-6 Brain structure; TGCT cis rs10883723 0.810 rs7917525 chr10:104246755 C/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs798554 0.704 rs798512 chr7:2782592 C/G cg25467336 chr7:2757616 NA -0.24 -4.62 -0.38 9.58e-6 Height; TGCT cis rs76419734 0.614 rs72669979 chr4:106523289 T/C cg24545054 chr4:106630052 GSTCD;INTS12 0.81 4.47 0.37 1.74e-5 Post bronchodilator FEV1; TGCT cis rs9814567 0.793 rs55940445 chr3:134306064 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.91 8.28 0.6 1.66e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4478858 0.746 rs10798832 chr1:31688630 C/G cg00250761 chr1:31883323 NA 0.29 4.78 0.39 4.9e-6 Alcohol dependence; TGCT cis rs7819412 0.595 rs2409712 chr8:10986837 A/C cg21775007 chr8:11205619 TDH -0.53 -5.34 -0.43 4.21e-7 Triglycerides; TGCT cis rs11098499 0.697 rs4560394 chr4:120313435 T/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs2115630 0.645 rs1107179 chr15:85198362 A/C cg11189052 chr15:85197271 WDR73 0.79 7.8 0.57 2.21e-12 P wave terminal force; TGCT cis rs11190604 1.000 rs2495737 chr10:102338344 T/C cg16342193 chr10:102329863 NA -0.41 -5.08 -0.41 1.37e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7296418 0.663 rs4553407 chr12:123750748 G/C cg00376283 chr12:123451042 ABCB9 0.73 6.44 0.5 2.36e-9 Platelet count; TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg23131131 chr22:24373011 LOC391322 -0.62 -6.23 -0.49 6.81e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg26116260 chr4:7069785 GRPEL1 1.13 11.1 0.71 2.59e-20 Monocyte percentage of white cells; TGCT cis rs7949030 1.000 rs7949030 chr11:62394881 A/G cg22862634 chr11:62369728 EML3;MTA2 0.57 6.73 0.52 5.53e-10 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2243480 1.000 rs35396113 chr7:65495461 C/T cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs2153535 0.541 rs9405386 chr6:8458067 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.3e-6 Motion sickness; TGCT cis rs7523273 0.554 rs2761434 chr1:207917499 C/T cg22525895 chr1:207977042 MIR29B2 -0.42 -6.09 -0.48 1.32e-8 Schizophrenia; TGCT cis rs78461346 1.000 rs76974730 chr17:80533261 C/T cg15014069 chr17:80540666 FOXK2 0.4 4.99 0.41 1.97e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs9811920 0.965 rs6767441 chr3:99863183 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.41 -4.59 -0.38 1.08e-5 Axial length; TGCT cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7552404 1.000 rs211723 chr1:76103030 C/T cg22875332 chr1:76189707 ACADM -0.79 -9.61 -0.65 1.12e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.24e-9 Blood metabolite levels; TGCT cis rs7246657 0.943 rs10404920 chr19:37881556 T/C cg18154014 chr19:37997991 ZNF793 1.0 6.69 0.52 6.81e-10 Coronary artery calcification; TGCT cis rs1218582 0.772 rs6686873 chr1:154913404 C/G cg03351412 chr1:154909251 PMVK 0.52 4.92 0.4 2.66e-6 Prostate cancer; TGCT cis rs9303401 0.659 rs35828828 chr17:56718205 C/T cg25039879 chr17:56429692 SUPT4H1 0.5 4.45 0.37 1.87e-5 Cognitive test performance; TGCT cis rs6725041 0.819 rs939225 chr2:213089002 T/C cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs4478037 0.822 rs9883177 chr3:33123354 T/C cg19404215 chr3:33155277 CRTAP 0.98 5.13 0.42 1.1e-6 Major depressive disorder; TGCT cis rs933688 1.000 rs1541674 chr5:90660447 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.03 9.42 0.65 3.21e-16 Smoking behavior; TGCT cis rs875971 1.000 rs4718344 chr7:65874381 C/A cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs36051895 0.632 rs10974987 chr9:5169302 G/T cg02405213 chr9:5042618 JAK2 -0.75 -9.77 -0.66 4.53e-17 Pediatric autoimmune diseases; TGCT cis rs612683 0.694 rs6688166 chr1:101000717 G/C cg06223162 chr1:101003688 GPR88 0.34 5.72 0.46 7.52e-8 Breast cancer; TGCT cis rs7267979 0.844 rs8184820 chr20:25250577 C/T cg03522245 chr20:25566470 NINL -0.57 -5.67 -0.45 9.54e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg05738196 chr6:26577821 NA 0.88 10.63 0.69 3.68e-19 Intelligence (multi-trait analysis); TGCT cis rs1577917 1.000 rs10455449 chr6:86592226 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.42 -0.44 3.02e-7 Response to antipsychotic treatment; TGCT cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs2486288 0.586 rs12909883 chr15:45572054 G/C cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.38 -0.44 3.57e-7 Glomerular filtration rate; TGCT cis rs523522 0.926 rs10849766 chr12:121025894 G/A cg12219531 chr12:120966889 COQ5 0.81 7.11 0.54 7.9e-11 High light scatter reticulocyte count; TGCT cis rs4730250 0.654 rs6947857 chr7:106787266 T/G cg02696742 chr7:106810147 HBP1 0.74 6.15 0.48 9.79e-9 Osteoarthritis; TGCT cis rs4788815 0.533 rs12102548 chr16:71929763 C/G cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 Metabolite levels; TGCT cis rs4888262 0.508 rs7193583 chr16:74649589 C/G cg01733217 chr16:74700730 RFWD3 0.74 7.47 0.56 1.23e-11 Testicular germ cell tumor; TGCT cis rs6427499 0.740 rs7551141 chr1:159892780 A/G cg15641364 chr1:159892206 TAGLN2 0.3 5.21 0.42 7.49e-7 Platelet distribution width; TGCT cis rs4149423 1.000 rs4149420 chr2:108913090 G/T cg06795125 chr2:108905320 SULT1C2 -0.46 -6.96 -0.53 1.75e-10 Lobe size; TGCT cis rs4746818 1.000 rs6480385 chr10:70904785 A/T cg11621586 chr10:70884670 VPS26A 1.23 11.01 0.7 4.3e-20 Left atrial antero-posterior diameter; TGCT cis rs1348850 0.958 rs12471741 chr2:178448196 A/G cg22681709 chr2:178499509 PDE11A -0.36 -4.46 -0.37 1.83e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs17331151 0.573 rs13080929 chr3:52885112 A/C cg07884673 chr3:53033167 SFMBT1 0.49 5.5 0.44 2.12e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7666738 0.791 rs12233867 chr4:98950233 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3820068 0.581 rs72645889 chr1:15930251 T/G cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs9291683 0.554 rs7668175 chr4:10125782 T/C cg00071950 chr4:10020882 SLC2A9 -0.43 -4.7 -0.39 6.69e-6 Bone mineral density; TGCT cis rs8180040 0.932 rs1038394 chr3:47464122 A/G cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs11190604 0.806 rs11190510 chr10:102157175 G/A cg23241863 chr10:102295624 HIF1AN 0.61 4.58 0.38 1.12e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3733585 0.638 rs7377625 chr4:9953099 T/C cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3015497 0.763 rs2934689 chr14:51118327 A/C cg04730355 chr14:51134070 SAV1 -0.65 -6.29 -0.49 4.85e-9 Mean platelet volume; TGCT cis rs8180040 0.967 rs4858856 chr3:47565424 G/A cg27129171 chr3:47204927 SETD2 0.61 7.13 0.54 7.45e-11 Colorectal cancer; TGCT cis rs868036 0.681 rs13329567 chr15:68104367 C/T cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs12042938 0.600 rs823165 chr1:231769446 T/A cg04892437 chr1:231737901 TSNAX-DISC1 0.48 4.86 0.4 3.4e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs7511006 0.798 rs11703673 chr22:50652427 A/G cg19026356 chr22:50624276 TRABD 0.63 5.61 0.45 1.26e-7 Obesity-related traits; TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs3008870 1.000 rs35365746 chr1:67438900 G/A cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs9368481 0.761 rs9357028 chr6:26967224 T/G cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.36 -4.58 -0.38 1.11e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs6484504 0.516 rs1999250 chr11:31287455 C/T cg14844989 chr11:31128820 NA -0.23 -4.49 -0.37 1.63e-5 Red blood cell count; TGCT cis rs11696501 0.688 rs6073788 chr20:44213773 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.79 -0.4 4.67e-6 Brain structure; TGCT cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs13118159 0.778 rs12640984 chr4:1338834 G/A cg22683308 chr4:1340831 KIAA1530 -0.64 -5.88 -0.47 3.53e-8 Longevity; TGCT cis rs3845702 0.736 rs72960660 chr2:180832482 A/G cg01881094 chr2:180872142 CWC22 1.04 6.58 0.51 1.21e-9 Schizophrenia; TGCT cis rs754133 0.964 rs894738 chr12:54417525 C/T cg16264616 chr12:54390824 NA 0.33 4.96 0.41 2.27e-6 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs13191362 0.938 rs35760705 chr6:163020637 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.76 0.46 6.37e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1443512 0.704 rs4759308 chr12:54329031 A/T cg17708016 chr12:54321992 NA 0.57 4.67 0.39 7.84e-6 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg04234412 chr22:24373322 LOC391322 -0.87 -10.25 -0.68 3.1e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9296661 0.798 rs1326574 chr6:51667219 A/G cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg08048268 chr3:133502702 NA -0.53 -7.22 -0.54 4.6e-11 Iron status biomarkers; TGCT cis rs67478160 0.572 rs8016014 chr14:104293798 G/C cg26031613 chr14:104095156 KLC1 -0.63 -6.37 -0.5 3.33e-9 Schizophrenia; TGCT cis rs4713118 0.597 rs172166 chr6:28020820 C/G cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs6665290 0.904 rs1045290 chr1:227178700 A/G cg10327440 chr1:227177885 CDC42BPA -1.01 -20.94 -0.88 1.57e-42 Myeloid white cell count; TGCT trans rs7221878 1.000 rs7220682 chr17:36188471 A/G cg03614664 chr22:41346948 RBX1 -1.39 -6.64 -0.51 8.97e-10 Macrophage inflammatory protein 1b levels; TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.76 -0.39 5.41e-6 Prudent dietary pattern; TGCT cis rs12477438 0.765 rs1115757 chr2:99660146 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs11585357 0.501 rs4262593 chr1:17594263 T/C cg08277548 chr1:17600880 PADI3 -0.81 -5.64 -0.45 1.08e-7 Hair shape; TGCT cis rs2486012 0.737 rs3791055 chr1:44265655 T/C cg12908607 chr1:44402522 ARTN -0.71 -5.54 -0.45 1.75e-7 Intelligence (multi-trait analysis); TGCT cis rs524281 0.861 rs10896091 chr11:65950825 T/C cg00563793 chr11:65837595 PACS1 0.57 4.91 0.4 2.8e-6 Electroencephalogram traits; TGCT cis rs9457247 0.935 rs1794697 chr6:167395410 C/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.06e-6 Crohn's disease; TGCT cis rs3096299 0.967 rs11648663 chr16:89466307 C/T cg02187348 chr16:89574699 SPG7 0.47 4.45 0.37 1.9e-5 Multiple myeloma (IgH translocation); TGCT cis rs4665809 0.878 rs4143538 chr2:26290178 A/C cg27170947 chr2:26402098 FAM59B -0.41 -4.67 -0.39 7.59e-6 Gut microbiome composition (summer); TGCT cis rs4506170 1.000 rs72712338 chr8:128340537 A/T cg07795030 chr8:128802207 NA -0.19 -4.46 -0.37 1.84e-5 Prostate cancer; TGCT cis rs3818285 0.556 rs941864 chr10:111656948 T/C cg00817464 chr10:111662876 XPNPEP1 -0.3 -5.04 -0.41 1.62e-6 Superior crus of antihelix expression; TGCT cis rs3784262 0.669 rs12909423 chr15:58292433 C/G cg12031962 chr15:58353849 ALDH1A2 0.43 6.21 0.49 7.49e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7027203 1.000 rs7027203 chr9:96562563 A/C cg14598338 chr9:96623480 NA 0.59 8.65 0.61 2.17e-14 DNA methylation (variation); TGCT trans rs8073060 0.586 rs4796100 chr17:33997657 G/T cg19694781 chr19:47549865 TMEM160 0.6 13.52 0.77 3.75e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9611565 0.525 rs1883827 chr22:41703579 A/G cg03806693 chr22:41940476 POLR3H -0.75 -7.26 -0.55 3.78e-11 Vitiligo; TGCT cis rs7940866 0.838 rs1991898 chr11:130801786 C/G cg05962950 chr11:130786565 SNX19 -0.74 -7.56 -0.56 7.91e-12 Schizophrenia; TGCT cis rs9638182 0.725 rs17145738 chr7:72982874 C/T cg14087351 chr7:73037990 MLXIPL -0.65 -5.18 -0.42 8.75e-7 Triglycerides; TGCT cis rs12497850 0.931 rs9311433 chr3:48863835 T/C cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.15e-6 Blood metabolite levels; TGCT cis rs8077889 0.917 rs72836545 chr17:41892602 A/G cg26893861 chr17:41843967 DUSP3 1.07 12.67 0.75 4.21e-24 Triglycerides; TGCT trans rs916888 0.779 rs430685 chr17:44859148 T/C cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2469997 1.000 rs1599476 chr8:120351800 C/T cg00681363 chr8:120844660 TAF2 0.65 4.45 0.37 1.9e-5 Hypertension (SNP x SNP interaction); TGCT cis rs61990749 0.597 rs2112136 chr14:78248952 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg22166914 chr1:53195759 ZYG11B 0.38 6.46 0.5 2.15e-9 Monocyte count; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg12419862 chr22:24373484 LOC391322 -0.86 -9.98 -0.67 1.4e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9394438 0.593 rs10947679 chr6:37543524 C/G cg00985040 chr6:37553208 NA 0.24 4.85 0.4 3.63e-6 IgG glycosylation; TGCT cis rs896854 0.573 rs11996455 chr8:95853708 G/A cg09323728 chr8:95962352 TP53INP1 -0.41 -4.79 -0.39 4.72e-6 Type 2 diabetes; TGCT cis rs12765878 0.557 rs2984133 chr10:105670848 T/A cg11005552 chr10:105648138 OBFC1 -0.39 -6.12 -0.48 1.15e-8 Coronary artery disease; TGCT cis rs295140 1.000 rs7559005 chr2:201161371 C/T cg04283868 chr2:201171347 SPATS2L 0.63 6.39 0.5 3.03e-9 QT interval; TGCT cis rs514406 0.505 rs427319 chr1:53178807 T/G cg25767906 chr1:53392781 SCP2 -0.47 -5.35 -0.43 4.15e-7 Monocyte count; TGCT cis rs7660520 0.524 rs6839881 chr4:183729137 A/T cg04181038 chr4:183730758 NA 0.61 5.76 0.46 6.22e-8 Pediatric autoimmune diseases; TGCT cis rs9733 0.566 rs72702554 chr1:150678234 A/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.49 0.37 1.63e-5 Tonsillectomy; TGCT cis rs9303401 0.659 rs16943176 chr17:56769887 G/A cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT trans rs10506458 0.915 rs17763441 chr12:63418335 T/C cg22491629 chr6:157744540 C6orf35 -0.98 -8.47 -0.61 6.02e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg05368731 chr17:41323189 NBR1 -0.92 -10.85 -0.7 1.07e-19 Menopause (age at onset); TGCT cis rs12477438 0.520 rs11123763 chr2:99750673 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs10751667 0.666 rs10902242 chr11:949700 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg11279151 chr3:101281821 RG9MTD1 -0.45 -9.64 -0.65 9.35e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Vitiligo; TGCT cis rs10744422 1.000 rs897386 chr12:123341289 A/C cg25930673 chr12:123319894 HIP1R -0.86 -5.09 -0.42 1.29e-6 Schizophrenia; TGCT cis rs9549260 0.564 rs9646110 chr13:41308301 A/T cg21288729 chr13:41239152 FOXO1 -0.87 -7.87 -0.58 1.5e-12 Red blood cell count; TGCT cis rs7959452 0.640 rs4761154 chr12:69705362 A/G cg11871910 chr12:69753446 YEATS4 -0.63 -6.37 -0.5 3.34e-9 Blood protein levels; TGCT cis rs1799949 0.683 rs55737636 chr17:41264739 C/T cg10047753 chr17:41438598 NA 0.78 7.25 0.55 3.96e-11 Menopause (age at onset); TGCT cis rs3741404 0.583 rs640999 chr11:63869425 C/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.72 7.32 0.55 2.78e-11 Platelet count; TGCT cis rs2456568 0.695 rs877341 chr11:93689293 C/T cg26875233 chr11:93583750 C11orf90 0.39 4.76 0.39 5.28e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2859741 0.967 rs534131 chr1:37484237 T/C cg09363841 chr1:37513479 NA -0.21 -4.89 -0.4 3.09e-6 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg10108389 chr3:44770937 ZNF501 -0.49 -4.9 -0.4 2.92e-6 Depressive symptoms; TGCT cis rs1843834 0.539 rs10177898 chr2:225437552 C/T cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs9916302 0.861 rs632202 chr17:37453294 C/A cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs6952808 0.609 rs4721185 chr7:1951109 T/C cg22963979 chr7:1858916 MAD1L1 -0.38 -5.63 -0.45 1.15e-7 Bipolar disorder and schizophrenia; TGCT cis rs3793683 0.858 rs1571145 chr10:134583672 C/G cg27286337 chr10:134555280 INPP5A -0.45 -6.76 -0.52 4.76e-10 Migraine; TGCT cis rs1042058 0.565 rs2480297 chr10:30754512 A/G cg18806716 chr10:30721971 MAP3K8 -0.57 -6.88 -0.53 2.69e-10 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg03609598 chr5:56110824 MAP3K1 0.66 4.54 0.38 1.3e-5 Initial pursuit acceleration; TGCT cis rs35306767 0.951 rs12777021 chr10:967270 T/C cg20503657 chr10:835505 NA 0.71 10.32 0.68 2.12e-18 Eosinophil percentage of granulocytes; TGCT trans rs1814175 0.791 rs10839395 chr11:49846274 G/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.37e-11 Height; TGCT cis rs1451375 1.000 rs4452748 chr7:50625056 A/C cg18232548 chr7:50535776 DDC -0.4 -6.3 -0.49 4.72e-9 Malaria; TGCT cis rs11190604 1.000 rs10883500 chr10:102238324 T/G cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2658782 1.000 rs2605583 chr11:93164957 T/A cg18152523 chr11:93063302 CCDC67 -0.65 -5.27 -0.43 5.74e-7 Pulmonary function decline; TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg24675658 chr1:53192096 ZYG11B -0.71 -8.23 -0.59 2.14e-13 Monocyte count; TGCT cis rs10992471 0.603 rs968040 chr9:95279985 C/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.68 -0.45 9.23e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4906332 0.901 rs4900575 chr14:103899169 G/C cg26031613 chr14:104095156 KLC1 -0.52 -4.59 -0.38 1.08e-5 Coronary artery disease; TGCT trans rs3824451 1.000 rs10985839 chr9:101075752 T/C cg11574975 chr1:112058304 ADORA3 -0.44 -6.71 -0.52 6.34e-10 Schizophrenia; TGCT cis rs595982 0.559 rs73061643 chr19:49368151 A/G cg17863274 chr19:49399704 TULP2 -0.47 -6.78 -0.52 4.43e-10 Red cell distribution width; TGCT cis rs7829975 0.502 rs7820738 chr8:8702607 C/G cg15556689 chr8:8085844 FLJ10661 -0.68 -6.41 -0.5 2.79e-9 Mood instability; TGCT cis rs2797160 0.905 rs1418640 chr6:125999866 G/A cg05901451 chr6:126070800 HEY2 -0.74 -6.48 -0.5 1.96e-9 Endometrial cancer; TGCT cis rs9303401 0.659 rs62083362 chr17:56846464 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs17376456 0.877 rs10476598 chr5:93367281 C/T cg25358565 chr5:93447407 FAM172A -1.0 -8.91 -0.62 5.42e-15 Diabetic retinopathy; TGCT cis rs7236492 0.577 rs7236190 chr18:77198217 T/C cg15644404 chr18:77186268 NFATC1 -0.27 -4.51 -0.38 1.49e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs1865760 1.000 rs12209482 chr6:25909229 T/G cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs10779751 0.734 rs2261317 chr1:11124979 A/G cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs7917772 0.582 rs4408249 chr10:104374653 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.24 0.43 6.78e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg08280861 chr8:58055591 NA -0.41 -5.0 -0.41 1.94e-6 Developmental language disorder (linguistic errors); TGCT cis rs6964587 1.000 rs6964587 chr7:91630620 G/T cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs589448 1.000 rs589448 chr12:69752200 A/G cg11871910 chr12:69753446 YEATS4 0.88 10.21 0.68 3.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs4689592 0.619 rs2359011 chr4:7066052 T/G cg06697600 chr4:7070879 GRPEL1 -0.47 -4.94 -0.41 2.42e-6 Monocyte percentage of white cells; TGCT cis rs4750440 0.637 rs2447010 chr10:14032115 T/C cg05755354 chr10:14372596 FRMD4A 0.3 4.77 0.39 5.1e-6 Adiponectin levels; TGCT cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg26818010 chr10:134567672 INPP5A -0.38 -5.39 -0.44 3.37e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9467711 0.585 rs3884025 chr6:25930088 G/A cg16898833 chr6:26189333 HIST1H4D 1.32 5.63 0.45 1.16e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6598955 0.724 rs12068388 chr1:26621596 G/A cg04990556 chr1:26633338 UBXN11 -0.9 -11.73 -0.73 7.95e-22 Obesity-related traits; TGCT cis rs3751972 0.696 rs7220473 chr17:26194116 T/C cg02948944 chr17:26242737 NA 0.38 5.1 0.42 1.21e-6 Fractional exhaled nitric oxide (childhood); TGCT cis rs2836633 0.929 rs11701577 chr21:40028906 C/T cg05519781 chr21:40033154 ERG 0.69 6.83 0.52 3.34e-10 Coronary artery disease; TGCT cis rs922182 0.557 rs7161764 chr15:64202744 C/T cg02919090 chr15:64263738 DAPK2 -0.38 -7.0 -0.53 1.4e-10 Blood protein levels; TGCT cis rs7927592 0.513 rs653056 chr11:68203625 T/C cg16797656 chr11:68205561 LRP5 0.28 5.13 0.42 1.08e-6 Total body bone mineral density; TGCT cis rs12549902 0.933 rs17659428 chr8:41513809 T/C cg00088007 chr8:41504566 NKX6-3 0.34 5.31 0.43 4.93e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs611744 0.647 rs10106246 chr8:109268710 T/C cg21045802 chr8:109455806 TTC35 0.71 7.25 0.55 4.03e-11 Dupuytren's disease; TGCT cis rs1005277 0.603 rs1998062 chr10:38457652 G/C cg13531842 chr10:38383804 ZNF37A -0.39 -4.64 -0.38 8.78e-6 Extrinsic epigenetic age acceleration; TGCT cis rs1505368 0.781 rs10197836 chr2:213274278 T/C cg20637307 chr2:213403960 ERBB4 0.47 4.47 0.37 1.71e-5 Symmetrical dimethylarginine levels; TGCT cis rs875971 0.862 rs10261398 chr7:65750164 A/G cg11764359 chr7:65958608 NA -0.57 -5.07 -0.41 1.4e-6 Aortic root size; TGCT cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg19318889 chr4:1322082 MAEA -0.21 -5.21 -0.42 7.67e-7 Obesity-related traits; TGCT trans rs1814175 0.618 rs1851843 chr11:50021846 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs9611565 0.649 rs738422 chr22:42123399 C/T cg03806693 chr22:41940476 POLR3H 0.96 9.91 0.66 2.06e-17 Vitiligo; TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg22166914 chr1:53195759 ZYG11B 0.37 5.95 0.47 2.49e-8 Monocyte count; TGCT cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs1061377 1.000 rs3796511 chr4:39122206 G/A cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs17665859 0.925 rs13258819 chr8:479636 G/A cg17960703 chr8:356704 FBXO25 1.2 4.7 0.39 6.74e-6 Bilirubin levels; TGCT cis rs2933343 0.700 rs876754 chr3:128627753 T/C cg11901034 chr3:128598214 ACAD9 -0.64 -6.1 -0.48 1.22e-8 IgG glycosylation; TGCT cis rs12681287 0.640 rs10095498 chr8:87425651 C/T cg27223183 chr8:87520930 FAM82B 0.89 6.36 0.5 3.45e-9 Caudate activity during reward; TGCT cis rs3125734 0.660 rs4979780 chr10:63992740 A/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.45 -0.37 1.91e-5 Rheumatoid arthritis; TGCT cis rs9393777 0.528 rs9467989 chr6:27064275 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.57 -5.64 -0.45 1.08e-7 Intelligence (multi-trait analysis); TGCT cis rs2742417 1.000 rs2742369 chr3:45754487 C/A cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs72945132 0.882 rs72947078 chr11:70197542 G/T cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs7940866 0.803 rs1865296 chr11:130882944 C/T cg05962950 chr11:130786565 SNX19 -0.68 -6.77 -0.52 4.64e-10 Schizophrenia; TGCT cis rs13256369 1.000 rs7820159 chr8:8576215 T/C cg18904891 chr8:8559673 CLDN23 0.63 5.84 0.46 4.38e-8 Obesity-related traits; TGCT cis rs35306767 0.761 rs12770910 chr10:1050318 A/G cg20503657 chr10:835505 NA 0.61 6.71 0.52 6.11e-10 Eosinophil percentage of granulocytes; TGCT cis rs11577318 0.853 rs2276712 chr1:26627478 T/C cg12733254 chr1:26682999 NA -0.2 -4.45 -0.37 1.89e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs35934224 0.783 rs16984299 chr22:19863593 C/T cg11182965 chr22:19864308 TXNRD2 0.33 4.94 0.41 2.49e-6 Glaucoma (primary open-angle); TGCT cis rs2836950 0.565 rs7278297 chr21:40625752 A/C cg06238570 chr21:40685208 BRWD1 -0.61 -6.34 -0.49 3.97e-9 Menarche (age at onset); TGCT cis rs17376456 0.597 rs10866760 chr5:93338335 G/A cg25358565 chr5:93447407 FAM172A -0.63 -5.95 -0.47 2.56e-8 Diabetic retinopathy; TGCT cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg03264133 chr6:25882463 NA 0.49 4.54 0.38 1.31e-5 Intelligence (multi-trait analysis); TGCT cis rs8016982 0.589 rs4640110 chr14:81692191 A/G cg01989461 chr14:81687754 GTF2A1 -0.67 -5.33 -0.43 4.54e-7 Schizophrenia; TGCT cis rs61008539 0.893 rs11765528 chr7:861952 C/T cg15782153 chr7:917662 C7orf20 0.52 6.26 0.49 5.66e-9 Perceived unattractiveness to mosquitoes; TGCT cis rs2439831 1.000 rs2584725 chr15:43793135 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.51 0.44 1.95e-7 Lung cancer in ever smokers; TGCT trans rs7824557 0.518 rs11777007 chr8:10801857 C/T cg15556689 chr8:8085844 FLJ10661 -0.82 -7.42 -0.55 1.62e-11 Retinal vascular caliber; TGCT cis rs968451 1.000 rs12628705 chr22:39693518 C/G cg17798944 chr22:39715225 SNORD43;RPL3 0.88 7.97 0.58 9.04e-13 Primary biliary cholangitis; TGCT cis rs10501293 0.585 rs4237639 chr11:42969584 A/G cg03447554 chr11:43094025 NA -0.43 -6.33 -0.49 4.12e-9 Cognitive performance; TGCT cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg07061783 chr6:25882402 NA -0.69 -6.81 -0.52 3.7e-10 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.903 rs12249828 chr10:894838 C/T cg26597838 chr10:835615 NA 0.74 10.28 0.68 2.64e-18 Eosinophil percentage of granulocytes; TGCT cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs1997103 1.000 rs6958022 chr7:55397389 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs3809566 0.676 rs9806544 chr15:63328360 G/A cg08198488 chr15:63333792 TPM1 -0.34 -5.0 -0.41 1.93e-6 Platelet count; TGCT cis rs2677744 0.719 rs877285 chr15:91452204 A/G cg23684204 chr15:91497937 RCCD1 0.36 5.17 0.42 9.11e-7 Attention deficit hyperactivity disorder; TGCT cis rs2204008 0.715 rs12815986 chr12:38343869 G/A cg13010199 chr12:38710504 ALG10B 0.61 4.84 0.4 3.79e-6 Bladder cancer; TGCT cis rs6952808 0.578 rs6949478 chr7:1841342 A/G cg03103944 chr7:1601985 NA 0.25 4.64 0.38 8.7e-6 Bipolar disorder and schizophrenia; TGCT trans rs4650994 0.525 rs4316329 chr1:178509333 C/T cg05059571 chr16:84539110 KIAA1609 -0.55 -11.44 -0.72 3.86e-21 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7246657 0.891 rs7257495 chr19:37823876 C/G cg18154014 chr19:37997991 ZNF793 0.74 5.08 0.42 1.34e-6 Coronary artery calcification; TGCT cis rs4253772 0.720 rs4253778 chr22:46630634 C/G cg09491104 chr22:46646882 C22orf40 -0.48 -4.92 -0.4 2.64e-6 LDL cholesterol;Cholesterol, total; TGCT trans rs7824557 0.547 rs2409745 chr8:11076635 G/T cg15556689 chr8:8085844 FLJ10661 0.82 8.18 0.59 2.8e-13 Retinal vascular caliber; TGCT cis rs2933343 0.672 rs1872545 chr3:128645039 G/C cg11901034 chr3:128598214 ACAD9 -0.65 -6.05 -0.48 1.55e-8 IgG glycosylation; TGCT cis rs3849570 0.925 rs2873054 chr3:81888255 A/C cg07356753 chr3:81810745 GBE1 -0.72 -6.65 -0.51 8.21e-10 Waist circumference;Body mass index; TGCT cis rs6088580 0.660 rs6059893 chr20:33105897 T/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs7312774 0.618 rs2888892 chr12:107328071 C/T cg16260113 chr12:107380972 MTERFD3 1.03 5.3 0.43 5.07e-7 Severe influenza A (H1N1) infection; TGCT cis rs6964587 0.541 rs6947170 chr7:91451471 A/G cg17063962 chr7:91808500 NA 0.73 6.69 0.52 6.75e-10 Breast cancer; TGCT trans rs1814175 0.904 rs7924371 chr11:49620595 C/T cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs7635838 0.859 rs9812885 chr3:11508326 G/C cg00170343 chr3:11313890 ATG7 0.67 6.21 0.49 7.42e-9 HDL cholesterol; TGCT cis rs13082711 0.595 rs7615321 chr3:27368010 A/G cg02860705 chr3:27208620 NA 0.46 6.65 0.51 8.25e-10 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2050392 1.000 rs2489864 chr10:30693744 C/G cg18806716 chr10:30721971 MAP3K8 -0.44 -5.17 -0.42 9.28e-7 Inflammatory bowel disease; TGCT cis rs1552244 1.000 rs7631678 chr3:10078816 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs739496 0.793 rs628825 chr12:111951850 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.59 0.45 1.4e-7 Platelet count; TGCT cis rs6815814 0.731 rs4504265 chr4:38773865 G/T cg02016764 chr4:38805732 TLR1 -0.28 -4.79 -0.4 4.63e-6 Breast cancer; TGCT cis rs539096 0.781 rs2970609 chr1:44097514 C/G cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Intelligence (multi-trait analysis); TGCT cis rs9457247 0.602 rs17615336 chr6:167506734 A/G cg07741184 chr6:167504864 NA 0.28 5.45 0.44 2.64e-7 Crohn's disease; TGCT cis rs7523273 0.597 rs4844619 chr1:207960708 C/T cg22525895 chr1:207977042 MIR29B2 -0.46 -6.74 -0.52 5.2400000000000005e-10 Schizophrenia; TGCT cis rs7781977 0.554 rs6421315 chr7:50355207 C/G cg01139861 chr7:50343298 IKZF1 0.49 5.8 0.46 5.19e-8 IgG glycosylation; TGCT cis rs333332 0.504 rs72962889 chr3:124329748 A/G cg04915618 chr3:124304960 KALRN 0.39 4.57 0.38 1.14e-5 Heschl's gyrus morphology; TGCT cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -6.31 -0.49 4.6e-9 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs13118159 0.836 rs2276903 chr4:1343405 A/G cg13395646 chr4:1353034 KIAA1530 -0.39 -4.47 -0.37 1.76e-5 Longevity; TGCT cis rs11971779 0.729 rs10464730 chr7:139002227 A/T cg07862535 chr7:139043722 LUC7L2 0.67 5.29 0.43 5.39e-7 Diisocyanate-induced asthma; TGCT cis rs514406 0.758 rs532242 chr1:53308665 C/G cg08736216 chr1:53307985 ZYG11A -0.28 -5.46 -0.44 2.49e-7 Monocyte count; TGCT cis rs1218582 0.628 rs12130132 chr1:154880386 C/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.53 -0.56 9.29e-12 Prostate cancer; TGCT cis rs11578119 0.933 rs12066718 chr1:170385570 C/A cg09767346 chr1:170501363 GORAB -0.72 -5.72 -0.46 7.52e-8 Male-pattern baldness; TGCT cis rs6938 0.534 rs8025447 chr15:75192222 T/G cg09165964 chr15:75287851 SCAMP5 0.56 5.29 0.43 5.31e-7 Breast cancer; TGCT cis rs7267979 0.586 rs6050439 chr20:25192331 T/C cg16686733 chr20:25566563 NINL 0.53 5.41 0.44 3.06e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611519 0.894 rs9611486 chr22:41458784 C/G cg03806693 chr22:41940476 POLR3H -0.67 -6.05 -0.48 1.57e-8 Neuroticism; TGCT cis rs7524258 0.900 rs2412151 chr1:7303216 G/C cg07173049 chr1:7289937 CAMTA1 0.28 4.56 0.38 1.21e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7666738 0.830 rs7679961 chr4:99000202 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7258465 1.000 rs8109573 chr19:18617151 G/T cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs909674 0.775 rs4821896 chr22:39833437 T/C cg24399712 chr22:39784796 NA -1.07 -11.12 -0.71 2.43e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs35000415 0.938 rs13236009 chr7:128663173 T/G cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 5.15 0.42 9.95e-7 Electroencephalogram traits; TGCT cis rs1153858 1.000 rs66528868 chr15:45668547 A/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs713587 0.934 rs6728219 chr2:25159172 T/C cg15423357 chr2:25149977 NA 0.59 5.96 0.47 2.49e-8 Body mass index in non-asthmatics; TGCT cis rs10131894 0.611 rs175002 chr14:75436466 C/G cg08847533 chr14:75593920 NEK9 0.68 7.05 0.53 1.12e-10 Coronary artery disease; TGCT cis rs9926296 0.656 rs2376881 chr16:89827011 C/G cg08627397 chr16:89984028 MC1R -0.29 -4.47 -0.37 1.77e-5 Vitiligo; TGCT cis rs9443645 0.869 rs4706747 chr6:79722639 A/G cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs968451 0.951 rs5750789 chr22:39725280 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.91 8.88 0.62 6.32e-15 Primary biliary cholangitis; TGCT cis rs7666738 0.830 rs34890015 chr4:99023769 A/T cg05340658 chr4:99064831 C4orf37 0.5 5.64 0.45 1.09e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.808 rs12105786 chr2:43676433 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9311474 0.713 rs352170 chr3:52236077 A/G cg10802521 chr3:52805072 NEK4 -0.56 -6.08 -0.48 1.35e-8 Electroencephalogram traits; TGCT cis rs116095464 0.510 rs7723883 chr5:270798 T/C cg22857025 chr5:266934 NA -0.34 -6.64 -0.51 8.6e-10 Breast cancer; TGCT cis rs4319547 0.737 rs7964138 chr12:122950375 A/G cg05707623 chr12:122985044 ZCCHC8 -0.64 -5.26 -0.43 6.1e-7 Body mass index; TGCT cis rs3820068 0.871 rs2861484 chr1:15812665 G/T cg05660106 chr1:15850417 CASP9 1.13 10.99 0.7 4.88e-20 Systolic blood pressure; TGCT cis rs1008375 1.000 rs62295634 chr4:17685346 C/A cg10189774 chr4:17578691 LAP3 0.54 4.95 0.41 2.37e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2456568 0.564 rs6483270 chr11:93624380 C/T cg26875233 chr11:93583750 C11orf90 -0.49 -6.13 -0.48 1.07e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs67311347 1.000 rs9968170 chr3:40494274 A/G cg13683864 chr3:40499215 RPL14 1.03 9.92 0.67 1.95e-17 Renal cell carcinoma; TGCT cis rs13191362 1.000 rs13199223 chr6:163001083 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs910316 0.712 rs175015 chr14:75457075 A/C cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.37e-7 Height; TGCT trans rs797680 0.822 rs2297707 chr1:93646207 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.89 -0.53 2.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9534288 0.797 rs4142548 chr13:46535350 A/G cg15192986 chr13:46630673 CPB2 -0.51 -7.21 -0.54 4.75e-11 Blood protein levels; TGCT cis rs6964587 1.000 rs28584017 chr7:91719168 G/A cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs4389656 0.826 rs395939 chr5:6734245 T/C cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs2070488 0.775 rs2268762 chr3:38516075 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.77 7.53 0.56 9.03e-12 Electrocardiographic conduction measures; TGCT cis rs7819412 0.594 rs60921132 chr8:10964969 T/A cg21775007 chr8:11205619 TDH -0.52 -5.16 -0.42 9.47e-7 Triglycerides; TGCT cis rs8072100 0.713 rs9807106 chr17:45457102 G/T cg08085267 chr17:45401833 C17orf57 -0.51 -5.58 -0.45 1.47e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2637266 0.667 rs2395406 chr10:78380519 G/A cg18941641 chr10:78392320 NA 0.43 5.53 0.44 1.81e-7 Pulmonary function; TGCT cis rs2067615 0.524 rs1922433 chr12:107077172 A/G cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs9303401 0.614 rs34900851 chr17:56566399 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.17 0.48 8.95e-9 Cognitive test performance; TGCT cis rs5769765 1.000 rs1033665 chr22:50252127 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.38 5.77 0.46 5.83e-8 Schizophrenia; TGCT cis rs7264396 0.790 rs6058294 chr20:34259396 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs7666738 0.830 rs1426662 chr4:98990319 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2738048 0.545 rs2738168 chr8:6824577 G/T cg24860332 chr8:6827800 DEFA10P -0.46 -6.8 -0.52 3.88e-10 IgA nephropathy; TGCT cis rs2153535 0.580 rs1932284 chr6:8477694 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs6500602 0.701 rs6500614 chr16:4573938 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 5.07 0.41 1.43e-6 Schizophrenia; TGCT cis rs1008375 0.966 rs4698636 chr4:17632834 T/C cg18681998 chr4:17616180 MED28 1.02 11.81 0.73 4.83e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg08280861 chr8:58055591 NA 0.48 5.17 0.42 9.03e-7 Developmental language disorder (linguistic errors); TGCT cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg22105103 chr4:187893119 NA 0.35 4.89 0.4 3.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2067615 0.599 rs10778508 chr12:107159405 A/G cg15890332 chr12:107067104 RFX4 -0.28 -5.64 -0.45 1.11e-7 Heart rate; TGCT cis rs1799949 0.965 rs9911630 chr17:41188342 A/G cg10047753 chr17:41438598 NA 0.6 5.49 0.44 2.13e-7 Menopause (age at onset); TGCT cis rs2797160 1.000 rs1739357 chr6:126019655 T/G cg05901451 chr6:126070800 HEY2 0.71 6.28 0.49 5.26e-9 Endometrial cancer; TGCT cis rs1577917 0.740 rs7752502 chr6:86410651 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.57 5.26 0.43 6.07e-7 Response to antipsychotic treatment; TGCT cis rs7659604 0.605 rs1396080 chr4:122740454 T/G cg06713675 chr4:122721982 EXOSC9 -0.63 -8.74 -0.62 1.39e-14 Type 2 diabetes; TGCT cis rs807669 0.524 rs11089258 chr22:19162276 C/T cg02655711 chr22:19163373 SLC25A1 0.26 5.06 0.41 1.45e-6 Metabolite levels; TGCT cis rs79996792 1.000 rs79996792 chr2:162443934 A/C cg22496339 chr2:162101262 NA 0.55 4.53 0.38 1.37e-5 Neuroticism; TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg07167872 chr1:205819463 PM20D1 0.57 6.98 0.53 1.59e-10 Menarche (age at onset); TGCT cis rs17125944 0.686 rs7141335 chr14:53336934 C/T cg00686598 chr14:53173677 PSMC6 -0.87 -4.5 -0.37 1.53e-5 Alzheimer's disease (late onset); TGCT cis rs9902453 0.838 rs7217638 chr17:28336772 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs9913156 0.639 rs72824971 chr17:4604270 A/G cg00122941 chr17:4613640 ARRB2 0.89 7.59 0.56 6.61e-12 Lymphocyte counts; TGCT cis rs7824557 0.591 rs2572452 chr8:11228254 C/T cg21775007 chr8:11205619 TDH -0.72 -7.46 -0.56 1.32e-11 Retinal vascular caliber; TGCT cis rs9296092 0.538 rs115770720 chr6:33517032 A/T cg13560919 chr6:33536144 NA -0.21 -4.74 -0.39 5.87e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7666738 0.830 rs10470951 chr4:99037051 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs929354 0.772 rs1182444 chr7:157024510 A/G cg05182265 chr7:156933206 UBE3C 0.4 9.05 0.63 2.54e-15 Body mass index; TGCT trans rs931812 0.825 rs34153562 chr8:101893441 T/C cg20993868 chr7:22813445 NA 0.42 9.03 0.63 2.75e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs7528684 0.872 rs6681271 chr1:157666644 A/G cg17134153 chr1:157670328 FCRL3 -0.25 -4.68 -0.39 7.31e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.73 7.52 0.56 9.57e-12 Blood metabolite levels; TGCT cis rs10791323 0.572 rs4353292 chr11:133742656 A/G cg15485101 chr11:133734466 NA 0.42 6.13 0.48 1.09e-8 Childhood ear infection; TGCT cis rs4268898 0.722 rs12185638 chr2:24382030 C/G cg02683114 chr2:24398427 C2orf84 0.19 4.57 0.38 1.14e-5 Asthma; TGCT cis rs79349575 0.715 rs9894220 chr17:46989154 C/T cg26022315 chr17:47021804 SNF8 0.54 5.31 0.43 4.96e-7 Type 2 diabetes; TGCT cis rs72615157 0.645 rs11771660 chr7:99851269 T/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.65 5.01 0.41 1.84e-6 Lung function (FEV1/FVC); TGCT cis rs12497850 0.931 rs4974085 chr3:48924900 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg13395646 chr4:1353034 KIAA1530 -0.38 -4.72 -0.39 6.28e-6 Obesity-related traits; TGCT cis rs10984561 0.881 rs12235956 chr9:122227703 G/A cg14242995 chr9:122249943 NA 0.73 6.32 0.49 4.34e-9 Pulmonary function decline; TGCT cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg18402987 chr7:1209562 NA 0.74 6.21 0.49 7.23e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1043515 0.607 rs4795318 chr17:36949053 C/T cg20826740 chr17:37024042 NA 0.43 4.45 0.37 1.87e-5 Height; TGCT cis rs7586879 0.616 rs12713422 chr2:25134497 A/C cg01884057 chr2:25150051 NA 0.36 7.1 0.54 8.63e-11 Body mass index; TGCT cis rs909674 0.524 rs5757670 chr22:39829736 G/A cg11247378 chr22:39784982 NA -0.73 -9.62 -0.65 1.05e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9303401 0.614 rs12948536 chr17:56580413 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.71 6.78 0.52 4.45e-10 Cognitive test performance; TGCT cis rs13118159 0.509 rs4974554 chr4:1356967 A/C cg05025164 chr4:1340916 KIAA1530 0.78 6.86 0.52 2.86e-10 Longevity; TGCT cis rs9913156 0.793 rs56020376 chr17:4560909 A/G cg23387401 chr17:4582204 PELP1 0.31 4.57 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg10411590 chr13:21900810 NA 0.34 4.75 0.39 5.46e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9473924 0.542 rs6901576 chr6:50926064 G/T cg14470998 chr6:50812995 TFAP2B -1.26 -7.3 -0.55 3.1e-11 Body mass index; TGCT cis rs137603 0.966 rs137585 chr22:39683444 G/A cg17798944 chr22:39715225 SNORD43;RPL3 -0.56 -5.14 -0.42 1.05e-6 Primary biliary cholangitis; TGCT trans rs9383153 1.000 rs2073518 chr6:16332730 T/C cg16722931 chr17:75312494 SEPT9 1.11 6.67 0.51 7.75e-10 Gambling; TGCT cis rs1062177 1.000 rs2964612 chr5:151198750 G/A cg00977110 chr5:151150581 G3BP1 0.4 4.5 0.38 1.51e-5 Preschool internalizing problems; TGCT cis rs4689388 0.926 rs10937717 chr4:6295087 T/A cg14416269 chr4:6271139 WFS1 0.39 5.05 0.41 1.56e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3771570 1.000 rs73018141 chr2:242221570 G/A cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs61524473 1 rs61524473 chr15:45646283 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Metabolite levels (small molecules and protein measures); TGCT cis rs3087591 0.960 rs2952976 chr17:29486152 G/A cg24425628 chr17:29625626 OMG;NF1 0.48 7.48 0.56 1.16e-11 Hip circumference; TGCT cis rs801193 0.904 rs4718403 chr7:66242729 C/G cg18876405 chr7:65276391 NA 0.35 5.2 0.42 8.09e-7 Aortic root size; TGCT cis rs7824557 0.564 rs2736302 chr8:11236419 T/C cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs2456568 0.805 rs2032400 chr11:93676937 G/A cg16099599 chr11:93583650 C11orf90 -0.38 -4.56 -0.38 1.2e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1552244 0.882 rs9812006 chr3:10022658 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.62 -0.51 9.94e-10 Alzheimer's disease; TGCT cis rs12497850 0.931 rs7621015 chr3:49016056 A/G cg07636037 chr3:49044803 WDR6 0.96 10.39 0.68 1.45e-18 Parkinson's disease; TGCT cis rs3806843 0.576 rs246009 chr5:140338069 A/G cg09824255 chr5:140014002 CD14 -0.25 -4.58 -0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs916888 0.821 rs70602 chr17:44859715 T/C cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12210905 0.688 rs72839479 chr6:27332910 G/A cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg16049864 chr8:95962084 TP53INP1 -0.7 -9.94 -0.67 1.76e-17 Type 2 diabetes; TGCT cis rs7312933 0.533 rs3747557 chr12:42717961 G/T cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.3e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs6163 0.508 rs11191381 chr10:104493444 C/T cg05855489 chr10:104503620 C10orf26 0.56 4.46 0.37 1.78e-5 Waist circumference;Hip circumference; TGCT cis rs10031466 1.000 rs2279550 chr4:189012728 G/C cg04086012 chr4:189060900 TRIML1 -0.2 -4.54 -0.38 1.31e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs28595532 0.920 rs115430947 chr4:119737149 C/A cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs78487399 0.808 rs77527404 chr2:43678387 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9928842 0.882 rs1107593 chr16:75261329 G/C cg09066997 chr16:75300724 BCAR1 0.28 5.01 0.41 1.85e-6 Alcoholic chronic pancreatitis; TGCT cis rs2120019 1.000 rs7175720 chr15:75348962 C/G cg17294928 chr15:75287854 SCAMP5 0.77 5.82 0.46 4.78e-8 Blood trace element (Zn levels); TGCT trans rs6089829 1.000 rs62207535 chr20:61669187 A/G cg17470723 chr8:74884337 TCEB1 0.75 7.11 0.54 8.2e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs7246657 0.722 rs1291 chr19:38229378 G/A cg03611452 chr19:38183253 ZNF781 -0.6 -5.03 -0.41 1.69e-6 Coronary artery calcification; TGCT cis rs6669919 0.647 rs894985 chr1:211673760 A/G cg26515805 chr1:211431828 RCOR3 -0.48 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs7014346 0.736 rs3847136 chr8:128407190 A/G cg04263511 chr8:128962092 PVT1 -0.38 -4.86 -0.4 3.42e-6 Colorectal cancer; TGCT cis rs11105298 0.891 rs11105302 chr12:89891366 A/G cg00757033 chr12:89920650 WDR51B -0.32 -4.97 -0.41 2.17e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10540 0.908 rs1044707 chr11:491334 G/T cg03352830 chr11:487213 PTDSS2 -0.26 -4.65 -0.39 8.4e-6 Body mass index; TGCT cis rs17767294 0.541 rs72845042 chr6:27568734 A/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Parkinson's disease; TGCT cis rs10992471 0.528 rs10992347 chr9:95220633 C/A cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9581857 0.685 rs10467687 chr13:28036516 G/A cg22138327 chr13:27999177 GTF3A 0.72 5.0 0.41 1.94e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs950776 0.613 rs12915539 chr15:78940795 T/A cg03762349 chr15:79060523 ADAMTS7 0.28 5.5 0.44 2.11e-7 Sudden cardiac arrest; TGCT cis rs910187 0.678 rs1046659 chr20:45817068 G/A cg27589058 chr20:45804311 EYA2 -0.32 -6.89 -0.53 2.51e-10 Migraine; TGCT cis rs853679 0.546 rs200989 chr6:27816442 A/G cg10876282 chr6:28092338 ZSCAN16 0.74 4.44 0.37 1.98e-5 Depression; TGCT trans rs11088226 0.645 rs7281844 chr21:33932435 T/C cg09050820 chr6:167586206 TCP10L2 0.76 6.79 0.52 4.22e-10 Gastritis; TGCT cis rs72781680 0.752 rs55859418 chr2:23904231 C/A cg08917208 chr2:24149416 ATAD2B 1.0 5.56 0.45 1.59e-7 Lymphocyte counts; TGCT cis rs3008870 0.536 rs2208576 chr1:67513401 C/G cg02640540 chr1:67518911 SLC35D1 -0.58 -5.57 -0.45 1.53e-7 Lymphocyte percentage of white cells; TGCT cis rs9303401 0.659 rs34275691 chr17:56736640 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs12541335 0.639 rs11135995 chr8:22200148 C/T cg26039829 chr8:22132926 PIWIL2 -0.26 -5.05 -0.41 1.56e-6 Hypertriglyceridemia; TGCT cis rs11711311 1.000 rs12637066 chr3:113527574 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs9914988 0.832 rs35033748 chr17:27179590 T/C cg20469991 chr17:27169893 C17orf63 -0.68 -5.0 -0.41 1.92e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT trans rs11088226 0.681 rs2833899 chr21:33933263 T/C cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT cis rs2228479 0.850 rs117880578 chr16:89910230 C/G cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs12477438 0.561 rs2084988 chr2:99655755 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT trans rs2727020 0.587 rs1164658 chr11:49298551 C/A cg15704280 chr7:45808275 SEPT13 0.72 8.25 0.6 1.92e-13 Coronary artery disease; TGCT cis rs7312933 0.670 rs2406568 chr12:42552297 G/C cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4319547 0.915 rs11058402 chr12:122981053 A/G cg23029597 chr12:123009494 RSRC2 -0.29 -4.87 -0.4 3.34e-6 Body mass index; TGCT cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg09222892 chr1:25734099 RHCE -0.41 -6.56 -0.51 1.31e-9 Plateletcrit;Mean corpuscular volume; TGCT cis rs8177253 1.000 rs8177262 chr3:133480652 A/G cg11941060 chr3:133502564 NA 0.26 5.34 0.43 4.19e-7 Iron status biomarkers; TGCT cis rs3806843 1.000 rs3733707 chr5:140181892 T/C cg19875535 chr5:140030758 IK 0.36 6.09 0.48 1.33e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs950169 0.922 rs12906983 chr15:84931022 G/A cg17173187 chr15:85201210 NMB 0.6 6.05 0.48 1.62e-8 Schizophrenia; TGCT cis rs9818758 0.607 rs12185979 chr3:49651970 C/G cg08550065 chr3:50336684 HYAL3;NAT6 1.15 4.5 0.37 1.53e-5 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7180079 0.514 rs6494488 chr15:65024204 G/A cg03791955 chr15:65024147 NA 0.28 5.52 0.44 1.93e-7 Monocyte count; TGCT cis rs10782582 0.593 rs74090712 chr1:76189098 A/G cg10523679 chr1:76189770 ACADM -0.65 -6.58 -0.51 1.2e-9 Daytime sleep phenotypes; TGCT cis rs7267979 1.000 rs2258719 chr20:25275843 C/T cg03522245 chr20:25566470 NINL 0.63 6.79 0.52 4.05e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs875971 1.000 rs4718344 chr7:65874381 C/A cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs12887734 0.524 rs17791722 chr14:104286210 C/T cg26031613 chr14:104095156 KLC1 -0.7 -6.04 -0.48 1.67e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg06634786 chr22:41940651 POLR3H -0.96 -8.69 -0.62 1.83e-14 Vitiligo; TGCT cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg24549020 chr5:56110836 MAP3K1 0.67 5.89 0.47 3.33e-8 Initial pursuit acceleration; TGCT cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs7727544 0.582 rs3805683 chr5:131535125 T/G cg24060327 chr5:131705240 SLC22A5 -0.44 -4.5 -0.37 1.56e-5 Blood metabolite levels; TGCT trans rs35851103 0.600 rs4841662 chr8:11843758 A/G cg15556689 chr8:8085844 FLJ10661 -0.81 -8.46 -0.6 6.38e-14 Neuroticism; TGCT cis rs28595532 0.668 rs58467651 chr4:119349011 T/G cg21605333 chr4:119757512 SEC24D 0.95 5.81 0.46 4.92e-8 Cannabis dependence symptom count; TGCT cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs3820068 0.608 rs12091750 chr1:16042766 T/C cg05660106 chr1:15850417 CASP9 0.69 6.45 0.5 2.28e-9 Systolic blood pressure; TGCT cis rs7666738 0.791 rs11729596 chr4:99045461 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.745 rs7483456 chr11:49774613 C/T cg15704280 chr7:45808275 SEPT13 -0.69 -8.05 -0.59 5.61e-13 Height; TGCT cis rs16866061 0.517 rs7580488 chr2:225473263 C/T cg22455342 chr2:225449267 CUL3 0.56 4.88 0.4 3.17e-6 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg03517284 chr6:25882590 NA -0.72 -6.58 -0.51 1.19e-9 Intelligence (multi-trait analysis); TGCT cis rs12478296 1.000 rs66612947 chr2:243035962 A/T cg06360820 chr2:242988706 NA -0.61 -4.75 -0.39 5.52e-6 Obesity-related traits; TGCT cis rs2066819 1.000 rs75754909 chr12:56726349 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs250677 0.687 rs1422581 chr5:148437386 C/T cg18129178 chr5:148520854 ABLIM3 0.42 6.16 0.48 9.34e-9 Breast cancer; TGCT cis rs9467711 0.559 rs12176129 chr6:26514940 C/T cg16898833 chr6:26189333 HIST1H4D 1.04 5.4 0.44 3.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg18876405 chr7:65276391 NA -0.38 -5.88 -0.47 3.53e-8 Aortic root size; TGCT cis rs875971 0.628 rs6974355 chr7:65841981 A/G cg00343986 chr7:65444356 GUSB 0.22 4.69 0.39 7.21e-6 Aortic root size; TGCT cis rs875971 0.508 rs10950045 chr7:66066373 T/C cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs370915 0.564 rs10027461 chr4:187837608 T/C cg19519643 chr4:187840862 NA -0.23 -4.62 -0.38 9.63e-6 Gout; TGCT cis rs11924390 0.749 rs822364 chr3:186452716 A/G cg12454167 chr3:186435060 KNG1 0.44 6.91 0.53 2.24e-10 Adiponectin levels; TGCT cis rs7666738 0.830 rs1115616 chr4:99006603 A/C cg17366294 chr4:99064904 C4orf37 0.71 7.3 0.55 3.08e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs11651000 0.857 rs57171311 chr17:45826168 A/G cg06532163 chr17:45867833 NA 0.37 5.23 0.43 6.97e-7 IgG glycosylation; TGCT trans rs2760061 0.659 rs708107 chr1:228189495 C/T cg16006296 chr10:38738647 LOC399744 -0.31 -6.97 -0.53 1.67e-10 Diastolic blood pressure; TGCT cis rs9457247 0.508 rs6941355 chr6:167506238 A/G cg07741184 chr6:167504864 NA 0.26 5.12 0.42 1.16e-6 Crohn's disease; TGCT cis rs10782582 0.593 rs4646960 chr1:76211103 C/A cg03433033 chr1:76189801 ACADM -0.6 -6.63 -0.51 9.16e-10 Daytime sleep phenotypes; TGCT cis rs6951245 0.507 rs11763865 chr7:1194274 G/A cg03188948 chr7:1209495 NA 0.49 4.68 0.39 7.33e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7582180 0.629 rs11693471 chr2:100948062 G/A cg08017756 chr2:100939284 LONRF2 -0.29 -4.63 -0.38 9.13e-6 Intelligence (multi-trait analysis); TGCT cis rs6933660 0.646 rs6911456 chr6:151778934 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.49 4.68 0.39 7.39e-6 Menarche (age at onset); TGCT trans rs12599106 0.629 rs1391904 chr16:34548934 C/T cg26668828 chr6:292823 DUSP22 -0.78 -8.15 -0.59 3.38e-13 Menopause (age at onset); TGCT cis rs7914558 1.000 rs6584540 chr10:104927634 A/G cg05855489 chr10:104503620 C10orf26 0.5 4.47 0.37 1.71e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6061231 0.597 rs624313 chr20:60927412 G/A cg06026331 chr20:60912101 LAMA5 -0.26 -4.69 -0.39 7.23e-6 Colorectal cancer; TGCT cis rs7582180 0.591 rs62148360 chr2:101006319 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs11098499 0.874 rs6826823 chr4:120112098 G/C cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs597539 0.552 rs10792006 chr11:68722306 T/C cg21862992 chr11:68658383 NA -0.34 -5.14 -0.42 1.03e-6 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs875971 0.825 rs801202 chr7:66023929 C/T cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs7666738 0.791 rs7660866 chr4:98961335 G/A cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6121246 0.909 rs6119725 chr20:30385557 G/T cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs9311474 0.632 rs6445528 chr3:52572447 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.51 -4.74 -0.39 5.85e-6 Electroencephalogram traits; TGCT cis rs7085104 0.700 rs10883785 chr10:104603588 A/G cg15744005 chr10:104629667 AS3MT -0.42 -5.28 -0.43 5.69e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg05368731 chr17:41323189 NBR1 1.1 11.12 0.71 2.38e-20 Menopause (age at onset); TGCT cis rs3617 0.625 rs7612624 chr3:52893426 T/C cg11645453 chr3:52864694 ITIH4 -0.29 -5.68 -0.45 9.09e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1801251 1.000 rs6746294 chr2:233583050 C/G cg08000102 chr2:233561755 GIGYF2 -0.57 -5.56 -0.45 1.58e-7 Coronary artery disease; TGCT cis rs858239 0.600 rs10233039 chr7:23143113 G/A cg05602783 chr7:23145260 KLHL7 -0.66 -5.45 -0.44 2.57e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10883723 0.810 rs7917525 chr10:104246755 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs597539 0.652 rs668576 chr11:68668208 A/G cg04772025 chr11:68637568 NA 0.6 6.78 0.52 4.26e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1865760 0.964 rs6932113 chr6:25913098 C/T cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs651907 0.535 rs34063583 chr3:101509948 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs28595532 0.582 rs71608361 chr4:119224081 T/C cg21605333 chr4:119757512 SEC24D 0.75 4.58 0.38 1.1e-5 Cannabis dependence symptom count; TGCT cis rs2204008 0.744 rs67889662 chr12:38327042 T/A cg26384229 chr12:38710491 ALG10B 0.83 7.29 0.55 3.15e-11 Bladder cancer; TGCT cis rs2019137 0.589 rs7560701 chr2:114026882 C/G cg27425262 chr2:113953981 PSD4;LOC440839 0.4 5.17 0.42 9.05e-7 Lymphocyte counts; TGCT cis rs9913156 0.793 rs11655166 chr17:4559302 T/A cg00122941 chr17:4613640 ARRB2 -0.88 -7.44 -0.56 1.46e-11 Lymphocyte counts; TGCT cis rs8050907 0.744 rs12446765 chr16:4569625 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.58 4.74 0.39 5.67e-6 Obesity-related traits; TGCT cis rs875971 0.660 rs801211 chr7:66015689 T/G cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs778371 0.676 rs7560115 chr2:233709465 T/G cg08000102 chr2:233561755 GIGYF2 -0.67 -7.64 -0.57 5.21e-12 Schizophrenia; TGCT cis rs698813 0.573 rs6544750 chr2:44490780 T/C cg00619915 chr2:44497795 NA -0.24 -5.5 -0.44 2.05e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg25767906 chr1:53392781 SCP2 0.49 5.77 0.46 5.88e-8 Monocyte count; TGCT cis rs7267979 1.000 rs6050573 chr20:25366065 C/G cg16686733 chr20:25566563 NINL 0.6 6.07 0.48 1.45e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9372498 0.536 rs9489460 chr6:118925754 C/T cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs11578119 0.933 rs12140161 chr1:170444010 A/G cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs4654899 0.965 rs6692081 chr1:21296363 T/C cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -8.31 -0.6 1.43e-13 Platelet count; TGCT cis rs2439831 0.702 rs2788 chr15:44064886 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs682748 0.810 rs6893113 chr5:17112370 A/G cg23987134 chr5:17158319 LOC285696 -0.21 -4.91 -0.4 2.78e-6 Hippocampal atrophy; TGCT cis rs10782582 0.593 rs12126155 chr1:76131555 C/G cg22875332 chr1:76189707 ACADM -0.55 -6.27 -0.49 5.53e-9 Daytime sleep phenotypes; TGCT cis rs986417 1.000 rs1018531 chr14:60970844 C/T cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs6880778 0.505 rs13186168 chr5:40376047 T/A cg01087697 chr5:40835557 RPL37 0.53 4.67 0.39 7.65e-6 Inflammatory bowel disease; TGCT cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg00786635 chr1:25594202 NA -0.58 -6.19 -0.49 8.24e-9 Plateletcrit;Mean corpuscular volume; TGCT cis rs473651 0.935 rs477041 chr2:239355995 C/G cg18131467 chr2:239335373 ASB1 -1.03 -15.58 -0.81 5.46e-31 Multiple system atrophy; TGCT cis rs6733011 0.578 rs4851170 chr2:99504323 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.49 4.67 0.39 7.81e-6 Bipolar disorder; TGCT cis rs12477438 0.520 rs6756650 chr2:99801800 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs11874712 1.000 rs9962458 chr18:43678625 G/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.12 0.42 1.11e-6 Migraine - clinic-based; TGCT cis rs9549260 0.755 rs7328677 chr13:41229905 A/G cg21288729 chr13:41239152 FOXO1 1.01 10.71 0.69 2.36e-19 Red blood cell count; TGCT cis rs4242434 0.597 rs11985023 chr8:22531463 C/T cg03733263 chr8:22462867 KIAA1967 -1.03 -14.0 -0.78 2.7e-27 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs5769707 0.967 rs1018812 chr22:50010073 C/T cg05373962 chr22:49881684 NA -0.3 -6.1 -0.48 1.22e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg06212747 chr3:49208901 KLHDC8B -0.66 -6.41 -0.5 2.71e-9 Menarche (age at onset); TGCT cis rs769267 0.896 rs11882123 chr19:19386339 A/G cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs9611565 1.000 rs5751086 chr22:41768862 C/T cg03806693 chr22:41940476 POLR3H -0.88 -9.56 -0.65 1.5e-16 Vitiligo; TGCT cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs2832191 1.000 rs6516891 chr21:30483070 C/T cg24692254 chr21:30365293 RNF160 -0.83 -8.72 -0.62 1.56e-14 Dental caries; TGCT cis rs7666738 0.830 rs10000573 chr4:99048785 G/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs12935418 0.616 rs8045512 chr16:80986307 A/G cg07676361 chr16:80966860 NA -0.35 -4.7 -0.39 6.87e-6 Mean corpuscular volume; TGCT cis rs931608 0.585 rs55851405 chr19:22541686 T/C cg23859931 chr19:22123797 NA -0.65 -4.81 -0.4 4.37e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs933688 1.000 rs11950530 chr5:90688740 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.15 0.59 3.39e-13 Smoking behavior; TGCT cis rs9467711 0.606 rs2072803 chr6:26392515 G/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.69 -0.39 7.03e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2439831 1.000 rs689754 chr15:43775895 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.26 0.43 6.09e-7 Lung cancer in ever smokers; TGCT cis rs4372836 0.704 rs966250 chr2:28974139 G/T cg09522027 chr2:28974177 PPP1CB -0.63 -6.25 -0.49 6.12e-9 Body mass index; TGCT cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs539096 0.781 rs2916568 chr1:44091274 A/G cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Intelligence (multi-trait analysis); TGCT cis rs7223966 1.000 rs2854219 chr17:61942682 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs6809651 0.524 rs10937240 chr3:185802823 C/T cg00760338 chr3:185826511 ETV5 -0.79 -6.45 -0.5 2.23e-9 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs17102884 0.506 rs887746 chr14:75403817 C/T cg08847533 chr14:75593920 NEK9 -0.61 -5.39 -0.44 3.49e-7 Neuroticism; TGCT cis rs9929218 1.000 rs12921546 chr16:68780069 G/A cg01251360 chr16:68772225 CDH1 0.29 4.87 0.4 3.27e-6 Colorectal cancer; TGCT cis rs9910055 0.593 rs2905983 chr17:42212429 T/G cg19774624 chr17:42201019 HDAC5 0.88 10.92 0.7 7.5e-20 Total body bone mineral density; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg25703541 chr22:24373054 LOC391322 -0.96 -12.23 -0.74 4.64e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.83 -0.52 3.35e-10 Colorectal cancer; TGCT cis rs13191362 0.872 rs13215538 chr6:163037975 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.5 0.61 5.17e-14 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9467711 0.516 rs548987 chr6:25869371 C/G cg03517284 chr6:25882590 NA -0.69 -4.6 -0.38 1.02e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs3820928 0.874 rs10199655 chr2:227892428 T/C cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs9467711 0.606 rs13203358 chr6:26590578 A/T cg16898833 chr6:26189333 HIST1H4D 1.02 5.25 0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11696501 0.739 rs4812933 chr20:44230792 C/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.79 -0.4 4.67e-6 Brain structure; TGCT cis rs950169 0.922 rs12911223 chr15:84831671 G/A cg17173187 chr15:85201210 NMB -0.54 -5.52 -0.44 1.87e-7 Schizophrenia; TGCT cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs548987 0.529 rs1165165 chr6:25862466 C/T cg03264133 chr6:25882463 NA -0.58 -4.84 -0.4 3.79e-6 Homocysteine levels; TGCT cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg19318889 chr4:1322082 MAEA -0.2 -5.12 -0.42 1.13e-6 Obesity-related traits; TGCT cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg25767906 chr1:53392781 SCP2 0.5 5.85 0.46 4.15e-8 Monocyte count; TGCT cis rs12701220 0.894 rs34712249 chr7:1036634 C/T cg27454412 chr7:1067447 C7orf50 -0.48 -4.47 -0.37 1.75e-5 Bronchopulmonary dysplasia; TGCT cis rs13102973 0.720 rs67429820 chr4:135888003 G/A cg14419869 chr4:135874104 NA 0.26 4.67 0.39 7.77e-6 Subjective well-being; TGCT cis rs2013441 1.000 rs2703791 chr17:20163529 A/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs1062177 0.756 rs2915826 chr5:151119963 G/A cg12924095 chr5:151150029 G3BP1 -0.34 -4.97 -0.41 2.17e-6 Preschool internalizing problems; TGCT cis rs11190604 1.000 rs2489049 chr10:102350732 G/A cg23241863 chr10:102295624 HIF1AN 0.71 5.36 0.43 3.84e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2204008 0.693 rs12372025 chr12:38202028 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.14 0.42 1.03e-6 Bladder cancer; TGCT cis rs2236918 0.710 rs2526698 chr1:242029101 T/C cg04158730 chr1:242011433 EXO1 0.56 5.2 0.42 8.05e-7 Menopause (age at onset); TGCT cis rs8028182 0.636 rs6495182 chr15:75814388 C/T cg20655648 chr15:75932815 IMP3 0.6 4.66 0.39 7.91e-6 Sudden cardiac arrest; TGCT cis rs950027 0.620 rs1153862 chr15:45631868 A/G cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT trans rs1814175 0.817 rs10769641 chr11:49960141 A/G cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs950169 0.544 rs12913702 chr15:85153184 G/A cg17173187 chr15:85201210 NMB 0.53 5.88 0.47 3.53e-8 Schizophrenia; TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg09436375 chr6:42928200 GNMT -0.42 -5.53 -0.44 1.78e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6061231 0.546 rs482220 chr20:60927482 G/A cg06026331 chr20:60912101 LAMA5 -0.26 -4.69 -0.39 7.23e-6 Colorectal cancer; TGCT cis rs6688613 1.000 rs10918606 chr1:166957249 A/G cg07049167 chr1:166818506 POGK 0.21 4.52 0.38 1.43e-5 Refractive astigmatism; TGCT cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg03806693 chr22:41940476 POLR3H 0.99 11.15 0.71 2.05e-20 Vitiligo; TGCT cis rs9926296 0.607 rs11076629 chr16:89875259 T/C cg04287289 chr16:89883240 FANCA 0.72 6.98 0.53 1.61e-10 Vitiligo; TGCT cis rs6558530 0.836 rs7461159 chr8:1716616 A/T cg09410841 chr8:1729607 CLN8 0.93 10.34 0.68 1.93e-18 Systolic blood pressure; TGCT cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.79 0.46 5.43e-8 Bipolar disorder; TGCT cis rs3820068 0.705 rs4646085 chr1:15825411 A/T cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT trans rs2727020 0.615 rs4980435 chr11:49591576 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.11e-10 Coronary artery disease; TGCT cis rs17102884 0.506 rs4899541 chr14:75403437 T/G cg08847533 chr14:75593920 NEK9 -0.62 -5.5 -0.44 2.09e-7 Neuroticism; TGCT cis rs11748684 1.000 rs72754917 chr5:42531009 G/C cg01169772 chr5:41904236 C5orf51 -0.9 -4.48 -0.37 1.67e-5 Response to taxane treatment (docetaxel); TGCT cis rs1218582 0.774 rs12036859 chr1:154859940 A/C cg16680214 chr1:154839983 KCNN3 0.42 9.26 0.64 7.57e-16 Prostate cancer; TGCT cis rs8033133 0.881 rs4344720 chr15:25324141 C/T cg14481604 chr15:25334117 SNORD116-22 -0.31 -6.77 -0.52 4.54e-10 Blood osmolality (transformed sodium); TGCT cis rs2836974 0.867 rs77959119 chr21:40542768 G/A cg06238570 chr21:40685208 BRWD1 0.74 6.6 0.51 1.1e-9 Cognitive function; TGCT trans rs1814175 0.527 rs7110797 chr11:49644096 T/C cg11707556 chr5:10655725 ANKRD33B -0.42 -8.27 -0.6 1.72e-13 Height; TGCT trans rs7726839 0.561 rs3915384 chr5:573395 G/T cg25482853 chr8:67687455 SGK3 1.06 9.11 0.63 1.81e-15 Obesity-related traits; TGCT cis rs2735413 0.564 rs79006334 chr16:78124954 A/G cg09132178 chr16:78079569 NA 0.35 4.47 0.37 1.77e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs3796352 1.000 rs13091844 chr3:53010271 C/T cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4819052 0.851 rs2838834 chr21:46665208 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 6.85 0.52 3.11e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs76954792 0.826 rs4795637 chr17:30027452 T/C cg18427091 chr17:30115417 NA -0.36 -4.67 -0.39 7.61e-6 Coronary artery disease; TGCT cis rs12477438 0.520 rs11692699 chr2:99730657 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs4665630 0.522 rs2551350 chr2:23913985 T/C cg08063864 chr2:24346004 PFN4;LOC375190 -1.22 -5.82 -0.46 4.81e-8 Hypertension; TGCT cis rs10193935 0.901 rs6752455 chr2:42543577 A/C cg27598129 chr2:42591480 NA -0.41 -5.59 -0.45 1.4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7100689 0.622 rs10749569 chr10:82129892 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg05785598 chr3:49045655 WDR6 0.36 4.86 0.4 3.51e-6 Menarche (age at onset); TGCT cis rs2562456 0.833 rs62110428 chr19:21613656 C/T cg25650185 chr19:21324782 ZNF431 -0.56 -4.45 -0.37 1.88e-5 Pain; TGCT cis rs6969780 0.630 rs3735530 chr7:27189982 C/T cg11410718 chr7:27170412 HOXA4 -0.46 -4.57 -0.38 1.18e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg12419862 chr22:24373484 LOC391322 0.86 9.94 0.67 1.77e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs936229 0.813 rs4886619 chr15:75106138 C/T cg10253484 chr15:75165896 SCAMP2 -0.66 -5.34 -0.43 4.28e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.47 -0.37 1.71e-5 Bipolar disorder; TGCT cis rs10771431 0.713 rs17794353 chr12:9361783 C/T cg08997352 chr12:9597637 DDX12 0.27 5.45 0.44 2.59e-7 Breast size; TGCT cis rs7809950 0.954 rs62482543 chr7:107080656 G/A cg23024343 chr7:107201750 COG5 -0.35 -5.56 -0.45 1.59e-7 Coronary artery disease; TGCT cis rs610932 0.517 rs673996 chr11:59994152 C/A cg18570331 chr11:60101691 MS4A6E 0.5 4.55 0.38 1.28e-5 Alzheimer's disease; TGCT cis rs950169 0.881 rs4081123 chr15:84956235 A/G cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs11098499 0.738 rs28408407 chr4:120376030 C/G cg09307838 chr4:120376055 NA 0.71 6.98 0.53 1.57e-10 Corneal astigmatism; TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs2836974 0.644 rs7281853 chr21:40693490 A/G cg17971929 chr21:40555470 PSMG1 -0.64 -5.81 -0.46 4.88e-8 Cognitive function; TGCT cis rs72627509 0.523 rs9637714 chr4:57731446 C/T cg26694713 chr4:57773883 REST -0.53 -5.5 -0.44 2.1e-7 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs769267 1.000 rs7246748 chr19:19433105 C/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs6912958 0.781 rs9450712 chr6:88193175 C/T cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10510102 0.872 rs11814703 chr10:123724289 T/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs459571 0.920 rs460154 chr9:136909309 C/T cg13789015 chr9:136890014 NCRNA00094 0.38 6.91 0.53 2.21e-10 Platelet distribution width; TGCT cis rs17102423 0.594 rs8010213 chr14:65552182 C/T cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.57e-9 Obesity-related traits; TGCT cis rs9359856 0.636 rs1980878 chr6:90314749 A/C cg13799429 chr6:90582589 CASP8AP2 0.45 4.61 0.38 9.8e-6 Bipolar disorder; TGCT cis rs8056742 0.730 rs35993081 chr16:85098003 G/C cg00229868 chr16:85520891 NA 0.38 4.77 0.39 5.03e-6 Amyotrophic lateral sclerosis; TGCT cis rs3812831 0.635 rs6560937 chr13:114945991 C/G cg06611532 chr13:114900021 NA 0.35 6.41 0.5 2.76e-9 Schizophrenia; TGCT cis rs7772486 0.875 rs2814869 chr6:146315509 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.55 -0.38 1.28e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.603 rs4506967 chr17:17990474 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.68 7.01 0.53 1.33e-10 Total body bone mineral density; TGCT cis rs2439831 0.681 rs3742969 chr15:43621947 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.69 0.62 1.84e-14 Lung cancer in ever smokers; TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg03807737 chr6:44242160 TMEM151B 0.31 7.24 0.55 4.22e-11 Phosphorus levels; TGCT cis rs4851266 0.966 rs12987662 chr2:100821548 C/A cg07810366 chr2:100720526 AFF3 -0.41 -5.82 -0.46 4.72e-8 Educational attainment; TGCT cis rs9611565 0.559 rs8139993 chr22:41995335 T/C cg03806693 chr22:41940476 POLR3H -1.01 -10.2 -0.68 4.07e-18 Vitiligo; TGCT cis rs12477438 0.834 rs6757019 chr2:99676936 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs3771570 0.901 rs3821285 chr2:242421314 A/G cg21155796 chr2:242212141 HDLBP -0.89 -6.82 -0.52 3.55e-10 Prostate cancer; TGCT cis rs1129187 0.720 rs9471972 chr6:42915021 G/A cg27588902 chr6:42928151 GNMT -0.5 -5.79 -0.46 5.54e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7833790 0.553 rs9693128 chr8:82706128 A/G cg27398817 chr8:82754497 SNX16 -0.71 -6.08 -0.48 1.34e-8 Diastolic blood pressure; TGCT cis rs9733 0.596 rs72702557 chr1:150680130 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs6967414 0.786 rs9639026 chr7:6746736 A/G cg00387323 chr7:6746715 ZNF12 0.79 4.8 0.4 4.49e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs6684514 1.000 rs2270291 chr1:156244992 G/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs16957091 0.647 rs9920182 chr15:43202550 G/A cg17935677 chr15:44119062 WDR76 0.52 4.71 0.39 6.44e-6 MGMT methylation in smokers; TGCT cis rs6964587 1.000 rs10228334 chr7:91713972 C/T cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs9527 0.590 rs7920868 chr10:104795409 C/T cg04362960 chr10:104952993 NT5C2 0.66 5.57 0.45 1.48e-7 Arsenic metabolism; TGCT cis rs600231 0.598 rs2508712 chr11:65232261 C/G cg17120908 chr11:65337727 SSSCA1 -0.55 -5.11 -0.42 1.17e-6 Bone mineral density; TGCT cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.791 rs6902410 chr6:145905261 G/A cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12497850 0.931 rs9311430 chr3:48845251 C/T cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs2050392 0.624 rs303444 chr10:30729347 C/T cg18806716 chr10:30721971 MAP3K8 -0.72 -9.67 -0.66 8.12e-17 Inflammatory bowel disease; TGCT cis rs13256369 1.000 rs12545771 chr8:8567977 C/G cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs524281 0.861 rs7943911 chr11:65943054 G/A cg00563793 chr11:65837595 PACS1 0.57 4.97 0.41 2.13e-6 Electroencephalogram traits; TGCT cis rs7474896 0.583 rs4934898 chr10:37990395 G/C cg13720705 chr10:37990370 NA 0.35 5.03 0.41 1.71e-6 Obesity (extreme); TGCT cis rs2153535 0.580 rs7767780 chr6:8453462 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs7772486 0.875 rs6938972 chr6:146410608 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.844 rs6132824 chr20:25238173 T/C cg14121845 chr20:25566513 NINL 0.49 4.96 0.41 2.24e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs617219 0.765 rs10053349 chr5:78475423 T/C cg23987322 chr5:78407566 BHMT 0.37 4.97 0.41 2.18e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7255045 0.742 rs2305796 chr19:12954141 C/T cg23899408 chr19:12877188 HOOK2 -0.6 -4.83 -0.4 3.96e-6 Mean corpuscular volume; TGCT cis rs2228479 0.681 rs2270461 chr16:89972345 C/T cg06558623 chr16:89946397 TCF25 -0.39 -4.98 -0.41 2.07e-6 Skin colour saturation; TGCT cis rs6582630 0.519 rs11181526 chr12:38360230 A/G cg26384229 chr12:38710491 ALG10B 0.79 6.98 0.53 1.61e-10 Drug-induced liver injury (flucloxacillin); TGCT trans rs7618501 0.633 rs2526751 chr3:50064867 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs2742417 0.967 rs9825559 chr3:45740278 T/C cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1480597 0.518 rs7893447 chr10:45203776 C/T cg12063947 chr10:45878068 ALOX5 0.26 4.44 0.37 2e-5 Parkinson's disease; TGCT cis rs12220238 0.722 rs6480743 chr10:76398765 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.64 5.19 0.42 8.46e-7 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs12681288 0.550 rs12549204 chr8:959085 G/T cg04851639 chr8:1020857 NA -0.27 -4.44 -0.37 1.94e-5 Schizophrenia; TGCT cis rs4665809 0.590 rs13022190 chr2:26515055 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs769267 0.965 rs4808200 chr19:19554803 C/T cg08509172 chr19:19383838 TM6SF2 -0.36 -4.76 -0.39 5.28e-6 Tonsillectomy; TGCT cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg22920501 chr2:26401640 FAM59B -0.78 -6.26 -0.49 5.88e-9 Gut microbiome composition (summer); TGCT cis rs7819412 0.505 rs34031674 chr8:10809490 G/C cg21775007 chr8:11205619 TDH -0.62 -5.65 -0.45 1.04e-7 Triglycerides; TGCT cis rs9372498 0.572 rs56082110 chr6:118909480 A/G cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs116095464 0.558 rs1971229 chr5:268187 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs2730245 0.645 rs4909282 chr7:158699797 T/C cg24397884 chr7:158709396 WDR60 0.35 4.48 0.37 1.65e-5 Height; TGCT cis rs9467603 0.800 rs28360585 chr6:25790356 A/T cg03517284 chr6:25882590 NA -0.66 -4.5 -0.37 1.53e-5 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.654 rs1011597 chr6:146075672 A/C cg13319975 chr6:146136371 FBXO30 0.52 4.66 0.39 8.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs748404 0.660 rs690367 chr15:43748304 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.47 -4.74 -0.39 5.81e-6 Lung cancer; TGCT cis rs17102423 0.755 rs35769504 chr14:65576857 G/A cg11161011 chr14:65562177 MAX -0.54 -7.49 -0.56 1.15e-11 Obesity-related traits; TGCT cis rs7954584 0.567 rs11612028 chr12:122387872 C/G cg22618164 chr12:122356400 WDR66 0.69 6.48 0.5 1.93e-9 Mean corpuscular volume; TGCT cis rs7611238 0.560 rs2000051 chr3:194997552 C/G cg27323046 chr3:195102265 ACAP2 -0.34 -4.51 -0.38 1.46e-5 Body mass index; TGCT cis rs3008870 1.000 rs3008888 chr1:67368965 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.84 0.73 4.25e-22 Lymphocyte percentage of white cells; TGCT cis rs1371867 0.810 rs2860518 chr8:101238120 G/T cg00191853 chr8:101177733 SPAG1 0.23 4.73 0.39 5.97e-6 Atrioventricular conduction; TGCT cis rs9916302 0.706 rs1054488 chr17:37687968 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -6.23 -0.49 6.8e-9 Glomerular filtration rate (creatinine); TGCT cis rs7246657 0.722 rs2291002 chr19:38033926 G/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT trans rs1864982 0.685 rs13358456 chr5:146209546 C/T cg07017998 chr4:733617 PCGF3 -0.29 -7.14 -0.54 6.83e-11 Alcohol dependence; TGCT cis rs6570726 0.791 rs9497357 chr6:145912888 G/A cg05347473 chr6:146136440 FBXO30 0.53 4.91 0.4 2.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg13395646 chr4:1353034 KIAA1530 -0.37 -4.63 -0.38 9.18e-6 Obesity-related traits; TGCT trans rs2727020 0.553 rs11040400 chr11:49518296 C/A cg15704280 chr7:45808275 SEPT13 -0.61 -6.81 -0.52 3.77e-10 Coronary artery disease; TGCT cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2288884 0.943 rs1433089 chr19:52506985 T/C cg13540795 chr19:52551618 ZNF432 -0.56 -4.99 -0.41 1.97e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs1008375 0.931 rs2098151 chr4:17577490 T/C cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 0.966 rs7270835 chr20:25435067 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs112591243 0.685 rs80124066 chr21:47912913 A/G cg10657630 chr21:48055338 PRMT2 1.06 5.21 0.42 7.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs7043114 0.525 rs1053441 chr9:95147840 T/A cg14311495 chr9:95764742 FGD3 -0.22 -4.52 -0.38 1.41e-5 Height; TGCT cis rs10089 1.000 rs2054444 chr5:127493206 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.81 -7.79 -0.57 2.27e-12 Ileal carcinoids; TGCT cis rs2816062 0.775 rs2816048 chr1:18893763 T/C cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs12210905 0.688 rs12215878 chr6:27336844 G/C cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs7258465 0.965 rs271622 chr19:18629277 A/G cg06462663 chr19:18546047 ISYNA1 0.21 4.96 0.41 2.24e-6 Breast cancer; TGCT cis rs910316 1.000 rs10873275 chr14:75531460 A/T cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs651907 0.557 rs11720745 chr3:101441690 G/A cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.78 -0.52 4.35e-10 Colorectal cancer; TGCT cis rs9457247 0.934 rs2345571 chr6:167403400 T/G cg23791538 chr6:167370224 RNASET2 -0.47 -4.63 -0.38 9.21e-6 Crohn's disease; TGCT cis rs597539 0.652 rs559032 chr11:68710847 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.82 7.64 0.57 5.01e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs72781680 0.799 rs2551332 chr2:23988950 T/C cg08917208 chr2:24149416 ATAD2B 0.75 4.62 0.38 9.32e-6 Lymphocyte counts; TGCT cis rs644799 0.544 rs1254935 chr11:95631470 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.54 5.15 0.42 9.81e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs797680 0.754 rs4847419 chr1:93845655 T/A cg17826107 chr1:92977322 EVI5 -0.23 -5.48 -0.44 2.25e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs8180040 0.966 rs1872164 chr3:47415100 G/A cg27129171 chr3:47204927 SETD2 -0.64 -7.39 -0.55 1.89e-11 Colorectal cancer; TGCT cis rs1997103 0.705 rs56301138 chr7:55396555 G/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs17401966 0.838 rs1556917 chr1:10400990 G/T cg19773385 chr1:10388646 KIF1B -0.24 -5.58 -0.45 1.46e-7 Hepatocellular carcinoma; TGCT cis rs10504229 0.906 rs2270609 chr8:58194684 G/A cg21724239 chr8:58056113 NA 0.38 4.7 0.39 6.91e-6 Developmental language disorder (linguistic errors); TGCT cis rs12220238 0.841 rs12098284 chr10:76047464 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.82 5.69 0.46 8.63e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9486719 1.000 rs2472890 chr6:96867646 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT trans rs212016 0.636 rs2630189 chr3:59968059 G/T cg05053403 chr12:133120676 FBRSL1 0.48 6.83 0.52 3.31e-10 Orofacial clefts; TGCT cis rs9393692 0.905 rs2393592 chr6:26285560 A/G cg13736514 chr6:26305472 NA -0.41 -5.77 -0.46 6.09e-8 Educational attainment; TGCT cis rs80282103 0.764 rs12247818 chr10:1110464 G/A cg08668510 chr10:1095578 IDI1 1.07 5.31 0.43 5e-7 Glomerular filtration rate (creatinine); TGCT cis rs11711311 0.955 rs10934247 chr3:113534941 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.72 -0.52 5.98e-10 IgG glycosylation; TGCT cis rs7937682 0.921 rs10789841 chr11:111469582 T/C cg09085632 chr11:111637200 PPP2R1B 0.87 7.32 0.55 2.71e-11 Primary sclerosing cholangitis; TGCT cis rs2034088 0.632 rs8067311 chr17:405603 T/G cg01214346 chr17:406501 NA -0.36 -5.48 -0.44 2.25e-7 Hip circumference adjusted for BMI; TGCT trans rs10953454 1.000 rs10259925 chr7:104491405 A/T cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs548987 0.529 rs651578 chr6:25873883 T/C cg03264133 chr6:25882463 NA -0.63 -5.41 -0.44 3.06e-7 Homocysteine levels; TGCT cis rs7044106 0.791 rs4836829 chr9:123482747 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 6.98 0.53 1.59e-10 Hip circumference adjusted for BMI; TGCT cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg06108461 chr20:60628389 TAF4 -0.7 -10.14 -0.67 5.74e-18 Body mass index; TGCT cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg05368731 chr17:41323189 NBR1 1.16 13.76 0.78 1.03e-26 Menopause (age at onset); TGCT cis rs265548 0.608 rs265545 chr19:17903465 C/T cg04517722 chr19:17905589 B3GNT3 0.46 5.88 0.47 3.63e-8 Tumor biomarkers; TGCT cis rs644799 0.735 rs10831432 chr11:95516040 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.28 0.6 1.63e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4889855 0.530 rs12451459 chr17:78589668 G/A cg16591659 chr17:78472290 NA 0.28 4.46 0.37 1.84e-5 Fractional excretion of uric acid; TGCT cis rs77633900 0.614 rs279999 chr15:76945466 C/T cg21673338 chr15:77095150 SCAPER -0.52 -4.92 -0.4 2.72e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs700651 0.821 rs700666 chr2:198673544 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial aneurysm; TGCT cis rs7224685 0.569 rs34540447 chr17:3994413 T/C cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs66573146 1.000 rs56350643 chr4:7017591 G/A cg01220768 chr4:7056774 TADA2B 0.41 5.11 0.42 1.2e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7267979 1.000 rs6107046 chr20:25442049 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12422267 0.536 rs7976530 chr12:132609140 C/T cg09764611 chr12:132620959 NA -0.37 -5.68 -0.45 9e-8 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs12497850 0.931 rs7431710 chr3:48935583 G/A cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs12579753 0.917 rs7313521 chr12:82205656 G/A cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs875971 0.522 rs7784623 chr7:65395034 T/G cg18876405 chr7:65276391 NA 0.37 5.89 0.47 3.34e-8 Aortic root size; TGCT cis rs899997 0.954 rs4887091 chr15:79043580 T/C cg04896959 chr15:78267971 NA 0.35 5.07 0.41 1.4e-6 Coronary artery disease or large artery stroke; TGCT cis rs36093844 0.948 rs11234451 chr11:85573702 T/A cg25872744 chr11:85566296 CCDC83 -0.5 -4.61 -0.38 9.71e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs483180 0.512 rs594400 chr1:120214275 G/T cg19096424 chr1:120255104 PHGDH -0.57 -5.43 -0.44 2.79e-7 Macular telangiectasia type 2; TGCT cis rs11719291 0.833 rs11715835 chr3:48770732 C/T cg00383909 chr3:49044727 WDR6 1.18 6.28 0.49 5.23e-9 Cognitive function; TGCT cis rs7246657 0.891 rs7253114 chr19:37988725 G/A cg18154014 chr19:37997991 ZNF793 0.71 5.05 0.41 1.51e-6 Coronary artery calcification; TGCT cis rs10883723 0.810 rs2296589 chr10:104248106 T/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg02353165 chr6:42928485 GNMT 0.97 9.93 0.67 1.83e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs589448 0.538 rs683790 chr12:69751434 T/G cg19645103 chr12:69753606 YEATS4 -0.63 -5.23 -0.42 7.11e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2228479 0.850 rs11076624 chr16:89855749 T/C cg06558623 chr16:89946397 TCF25 0.47 4.58 0.38 1.14e-5 Skin colour saturation; TGCT cis rs7666738 0.830 rs4699584 chr4:98952019 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.881 rs62029596 chr15:84955434 A/G cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs137603 0.644 rs94852 chr22:39712334 T/C cg17798944 chr22:39715225 SNORD43;RPL3 -0.66 -7.12 -0.54 7.74e-11 Primary biliary cholangitis; TGCT cis rs12477438 0.798 rs7606635 chr2:99644782 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12210905 0.687 rs12191649 chr6:27421208 A/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs727479 0.502 rs4774583 chr15:51505993 A/G cg19946085 chr15:51559439 CYP19A1 -0.31 -4.54 -0.38 1.3e-5 Estradiol levels; TGCT cis rs1372520 0.684 rs10008964 chr4:90744721 G/A cg01966878 chr4:90757139 SNCA -0.3 -4.69 -0.39 7.05e-6 Neuroticism; TGCT cis rs9650657 0.589 rs12542037 chr8:10758496 G/A cg27411982 chr8:10470053 RP1L1 0.22 4.72 0.39 6.18e-6 Neuroticism; TGCT cis rs10875746 0.951 rs58865997 chr12:48566873 G/A cg20731937 chr12:48336164 NA 0.63 4.99 0.41 2.02e-6 Longevity (90 years and older); TGCT cis rs1005277 0.579 rs2474575 chr10:38387901 C/T cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs12477438 0.520 rs6756650 chr2:99801800 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs4886238 0.539 rs4886241 chr13:61157717 T/C cg23734418 chr13:61221316 NA -0.25 -4.46 -0.37 1.81e-5 Menopause (age at onset); TGCT cis rs7439150 1.000 rs1800789 chr4:155482743 G/A cg22130008 chr4:155548532 NA -0.47 -5.8 -0.46 5.25e-8 Fibrinogen levels; TGCT cis rs8002180 0.959 rs9584288 chr13:95920458 A/G cg24476569 chr13:95954382 ABCC4 0.39 4.82 0.4 4.04e-6 Blood metabolite levels; TGCT cis rs4455778 0.559 rs6583511 chr7:49122876 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs854765 0.693 rs8079321 chr17:17760789 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.65 0.57 4.87e-12 Total body bone mineral density; TGCT trans rs7726839 0.574 rs11134149 chr5:637277 A/G cg11887960 chr12:57824829 NA 1.05 9.27 0.64 7.22e-16 Obesity-related traits; TGCT cis rs210152 0.531 rs4713634 chr6:33514708 T/C cg07735790 chr6:34101545 GRM4 -0.52 -4.75 -0.39 5.46e-6 Schizophrenia; TGCT cis rs9926296 0.568 rs886950 chr16:89836872 T/C cg03388025 chr16:89894329 SPIRE2 0.5 8.67 0.61 2.03e-14 Vitiligo; TGCT cis rs829880 1.000 rs829880 chr12:98845331 G/T cg25150519 chr12:98850993 NA 0.63 6.32 0.49 4.29e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.549 rs7577896 chr2:26524493 C/T cg04944784 chr2:26401820 FAM59B 0.73 4.68 0.39 7.31e-6 Gut microbiome composition (summer); TGCT cis rs1156327 0.655 rs4238672 chr16:19325519 T/C cg02978544 chr16:19716338 NA -0.42 -4.44 -0.37 1.93e-5 Periodontal disease-related phenotypes; TGCT cis rs2130392 1.000 rs2130392 chr4:185639169 A/G cg14471096 chr4:185570637 CCDC111;CASP3 0.55 5.46 0.44 2.54e-7 Kawasaki disease; TGCT cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg03517284 chr6:25882590 NA -0.52 -5.28 -0.43 5.67e-7 Blood metabolite levels; TGCT cis rs4555082 0.834 rs2816623 chr14:105733295 G/A cg01266790 chr14:105781312 PACS2 0.56 4.6 0.38 1.04e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs1887596 0.624 rs9553856 chr13:27136058 A/G cg01312412 chr13:27282625 NA 0.27 4.74 0.39 5.72e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs9916302 0.555 rs12940193 chr17:37652178 T/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg21724239 chr8:58056113 NA 0.48 5.17 0.42 9.18e-7 Developmental language disorder (linguistic errors); TGCT cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs2945232 1 rs2945232 chr8:8098038 T/C cg15462221 chr8:8086144 FLJ10661 -0.53 -4.85 -0.4 3.61e-6 Schizophrenia; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.52 5.76 0.46 6.2e-8 Lymphocyte counts; TGCT cis rs9291683 0.632 rs10939669 chr4:10045827 A/G cg00071950 chr4:10020882 SLC2A9 0.68 8.74 0.62 1.38e-14 Bone mineral density; TGCT cis rs9291683 0.566 rs13115776 chr4:10040189 C/G cg00071950 chr4:10020882 SLC2A9 0.6 6.89 0.53 2.49e-10 Bone mineral density; TGCT cis rs2486288 0.656 rs1719232 chr15:45572072 A/G cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.17 -0.42 9.1e-7 Glomerular filtration rate; TGCT cis rs926938 0.541 rs360623 chr1:115407268 G/C cg12756093 chr1:115239321 AMPD1 0.42 6.39 0.5 2.99e-9 Autism; TGCT cis rs9916302 0.904 rs3964723 chr17:37403979 C/T cg15445000 chr17:37608096 MED1 0.3 4.44 0.37 1.97e-5 Glomerular filtration rate (creatinine); TGCT trans rs1005277 0.579 rs1740745 chr10:38520056 T/C cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg09436375 chr6:42928200 GNMT -0.42 -5.41 -0.44 3.16e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6909279 0.933 rs7761420 chr6:151872567 C/T cg14416726 chr6:151773293 C6orf211;RMND1 0.51 4.47 0.37 1.75e-5 Bone mineral density; TGCT cis rs12681288 0.645 rs35040046 chr8:989973 C/T cg04851639 chr8:1020857 NA -0.29 -4.67 -0.39 7.76e-6 Schizophrenia; TGCT trans rs7726839 0.526 rs11960159 chr5:568685 C/T cg25482853 chr8:67687455 SGK3 1.14 9.45 0.65 2.78e-16 Obesity-related traits; TGCT cis rs6952808 0.609 rs10230383 chr7:1950113 T/C cg22963979 chr7:1858916 MAD1L1 -0.37 -5.58 -0.45 1.42e-7 Bipolar disorder and schizophrenia; TGCT cis rs66573146 1.000 rs6812771 chr4:6964048 G/A cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs11578119 0.933 rs1537390 chr1:170473659 C/G cg09767346 chr1:170501363 GORAB -0.67 -5.36 -0.43 3.85e-7 Male-pattern baldness; TGCT cis rs4273100 0.512 rs2233072 chr17:19281828 T/G cg03910582 chr17:19030146 GRAPL -0.45 -6.21 -0.49 7.38e-9 Schizophrenia; TGCT trans rs7726839 0.540 rs74553517 chr5:665671 C/T cg25482853 chr8:67687455 SGK3 1.19 10.53 0.69 6.56e-19 Obesity-related traits; TGCT cis rs13256369 0.802 rs12680019 chr8:8561698 A/G cg17143192 chr8:8559678 CLDN23 0.54 5.03 0.41 1.64e-6 Obesity-related traits; TGCT cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg17554472 chr22:41940697 POLR3H -0.46 -4.69 -0.39 7.09e-6 Vitiligo; TGCT cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg08923669 chr16:420230 MRPL28 -0.54 -5.21 -0.42 7.56e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs524281 0.861 rs10896085 chr11:65913832 A/T cg00563793 chr11:65837595 PACS1 0.58 4.94 0.41 2.44e-6 Electroencephalogram traits; TGCT cis rs778371 1.000 rs778371 chr2:233743109 A/G cg08000102 chr2:233561755 GIGYF2 -0.57 -6.12 -0.48 1.12e-8 Schizophrenia; TGCT cis rs2980439 0.818 rs2948300 chr8:8106508 C/T cg06636001 chr8:8085503 FLJ10661 0.88 8.69 0.62 1.79e-14 Neuroticism; TGCT cis rs394563 0.591 rs237018 chr6:149743930 A/G cg16235748 chr6:149772707 ZC3H12D -0.42 -4.89 -0.4 3.06e-6 Dupuytren's disease; TGCT cis rs854765 0.647 rs62073573 chr17:17976354 G/A cg04398451 chr17:18023971 MYO15A -0.35 -5.83 -0.46 4.6e-8 Total body bone mineral density; TGCT cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg09222892 chr1:25734099 RHCE 0.42 6.95 0.53 1.85e-10 Erythrocyte sedimentation rate; TGCT cis rs6598955 0.671 rs58038522 chr1:26582713 C/T cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs13256369 0.851 rs13255061 chr8:8563834 G/A cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs56104184 0.775 rs56349331 chr19:49403009 T/A cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2013441 1.000 rs2526475 chr17:20136216 T/C cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs7439150 1.000 rs7439150 chr4:155481541 G/A cg22130008 chr4:155548532 NA -0.44 -5.57 -0.45 1.49e-7 Fibrinogen levels; TGCT cis rs12497850 0.931 rs7628719 chr3:48995487 C/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.41 -0.44 3.09e-7 Parkinson's disease; TGCT cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7822232 0.908 rs6558297 chr8:145143934 C/T cg14631276 chr8:145163102 KIAA1875 -0.56 -5.05 -0.41 1.55e-6 Blood metabolite levels; TGCT cis rs1023500 0.552 rs5758566 chr22:42454354 G/A cg15557168 chr22:42548783 NA -0.21 -5.3 -0.43 5.2e-7 Schizophrenia; TGCT cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs908922 0.523 rs4845786 chr1:152510144 A/G cg20991723 chr1:152506922 NA 0.45 5.98 0.47 2.27e-8 Hair morphology; TGCT cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg24690094 chr11:67383802 NA 0.31 4.69 0.39 7.04e-6 Mean corpuscular volume; TGCT cis rs4654899 0.865 rs9426730 chr1:21452255 A/T cg01072550 chr1:21505969 NA -0.5 -7.77 -0.57 2.56e-12 Superior frontal gyrus grey matter volume; TGCT trans rs916888 0.610 rs142167 chr17:44795234 C/T cg22968622 chr17:43663579 NA -1.03 -10.02 -0.67 1.12e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1153858 0.848 rs9806699 chr15:45740392 G/A cg26924012 chr15:45694286 SPATA5L1 0.97 11.57 0.72 1.92e-21 Homoarginine levels; TGCT cis rs9291683 0.588 rs2240724 chr4:10021290 G/C cg11266682 chr4:10021025 SLC2A9 0.68 9.96 0.67 1.58e-17 Bone mineral density; TGCT cis rs2721195 0.654 rs4610795 chr8:145881333 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 -0.89 -9.49 -0.65 2.18e-16 Age at first birth; TGCT cis rs2235642 0.750 rs1894649 chr16:1657284 C/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.27 -4.64 -0.38 8.77e-6 Coronary artery disease; TGCT cis rs10751667 0.643 rs11246362 chr11:969818 C/T cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.66e-13 Alzheimer's disease (late onset); TGCT cis rs889312 0.500 rs1867731 chr5:56132115 C/G cg12311346 chr5:56204834 C5orf35 -0.49 -5.44 -0.44 2.77e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs7666738 0.761 rs28758886 chr4:99059704 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3740393 0.562 rs1339919 chr10:104534448 A/G cg05855489 chr10:104503620 C10orf26 0.8 6.47 0.5 2.07e-9 Microalbuminuria; TGCT cis rs9303401 0.659 rs7224276 chr17:56897827 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs9325144 0.647 rs12231313 chr12:39101929 C/T cg10518543 chr12:38710700 ALG10B -0.49 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs1044826 0.597 rs6772199 chr3:139178133 C/T cg00490450 chr3:139108681 COPB2 0.52 4.53 0.38 1.39e-5 Obesity-related traits; TGCT cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg06221963 chr1:154839813 KCNN3 0.68 11.66 0.72 1.12e-21 Prostate cancer; TGCT cis rs6665290 0.582 rs72764213 chr1:227207391 C/T cg11404489 chr1:228071452 NA -0.19 -4.57 -0.38 1.18e-5 Myeloid white cell count; TGCT cis rs711245 0.573 rs11899523 chr2:36800918 T/C cg15105969 chr2:36825350 FEZ2 0.58 5.27 0.43 5.88e-7 Height; TGCT cis rs7824557 0.592 rs2572371 chr8:11223793 G/T cg21775007 chr8:11205619 TDH 0.63 5.9 0.47 3.29e-8 Retinal vascular caliber; TGCT cis rs6964587 1.000 rs7455444 chr7:91639313 C/T cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs1461503 0.838 rs7126962 chr11:122830551 T/C cg27398637 chr11:122830231 C11orf63 -0.41 -4.77 -0.39 5.14e-6 Menarche (age at onset); TGCT cis rs3885907 0.520 rs4584668 chr13:31319553 A/T cg22282089 chr13:30686841 NA -0.22 -4.54 -0.38 1.33e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT cis rs734999 0.545 rs41300092 chr1:2537838 C/T cg18854424 chr1:2615690 NA 0.41 4.58 0.38 1.13e-5 Ulcerative colitis; TGCT cis rs13188771 0.634 rs10043001 chr5:100894557 T/G cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7659604 0.676 rs7691955 chr4:122700462 A/T cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.72 -0.46 7.66e-8 Type 2 diabetes; TGCT cis rs72945132 0.882 rs7950916 chr11:70210001 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs2456568 0.548 rs1607402 chr11:93660732 T/G cg26875233 chr11:93583750 C11orf90 -0.41 -4.9 -0.4 2.96e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs10802346 0.545 rs1770003 chr1:246408356 A/G cg22732515 chr19:44031385 ETHE1 0.84 6.78 0.52 4.34e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg10802521 chr3:52805072 NEK4 -0.71 -8.85 -0.62 7.46e-15 Bipolar disorder; TGCT cis rs1975974 0.511 rs66461325 chr17:21755430 A/G cg18423549 chr17:21743878 NA -0.63 -5.67 -0.45 9.38e-8 Psoriasis; TGCT cis rs17433780 0.892 rs72726528 chr1:89455980 C/A cg09516651 chr1:89888402 LOC400759 0.32 5.89 0.47 3.35e-8 Carotid intima media thickness; TGCT cis rs4665809 1.000 rs4233710 chr2:26291565 G/A cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs2836974 0.932 rs2836953 chr21:40617483 G/A cg11890956 chr21:40555474 PSMG1 1.11 12.48 0.75 1.21e-23 Cognitive function; TGCT cis rs11874712 1.000 rs9961065 chr18:43653327 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.11 0.42 1.19e-6 Migraine - clinic-based; TGCT cis rs7945705 0.782 rs2742545 chr11:8884308 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.41 -4.5 -0.37 1.56e-5 Hemoglobin concentration; TGCT cis rs9291683 0.552 rs10939655 chr4:10014642 A/T cg11266682 chr4:10021025 SLC2A9 0.73 11.04 0.7 3.63e-20 Bone mineral density; TGCT cis rs1429606 1.000 rs1881546 chr5:87246567 A/T cg09451457 chr5:87440246 NA 0.72 4.72 0.39 6.19e-6 Number of children (6+ vs. 0 or 1); TGCT cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg17747265 chr1:1875780 NA -0.42 -7.88 -0.58 1.42e-12 Body mass index; TGCT cis rs3772130 0.923 rs13434284 chr3:121482842 C/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs2836633 0.929 rs4143428 chr21:40030582 G/T cg05519781 chr21:40033154 ERG 0.69 6.83 0.52 3.34e-10 Coronary artery disease; TGCT cis rs477895 0.713 rs12787852 chr11:63954648 G/A cg23719950 chr11:63933701 MACROD1 -0.71 -5.87 -0.47 3.82e-8 Mean platelet volume; TGCT cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg07061783 chr6:25882402 NA -0.5 -5.47 -0.44 2.33e-7 Blood metabolite levels; TGCT cis rs4699052 0.662 rs6828151 chr4:104284756 C/G cg16532752 chr4:104119610 CENPE -0.5 -4.75 -0.39 5.48e-6 Testicular germ cell tumor; TGCT cis rs2730260 0.537 rs56260213 chr7:158875921 C/T cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs904251 0.580 rs62408367 chr6:37444813 G/A cg01843034 chr6:37503916 NA -0.46 -5.61 -0.45 1.27e-7 Cognitive performance; TGCT cis rs1008375 0.932 rs4698627 chr4:17605959 T/C cg10189774 chr4:17578691 LAP3 0.63 5.38 0.43 3.58e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs4808199 0.649 rs12983940 chr19:19516431 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 4.98 0.41 2.12e-6 Nonalcoholic fatty liver disease; TGCT cis rs6598955 0.543 rs79778574 chr1:26538482 A/G cg24519413 chr1:26490540 NA -0.25 -4.61 -0.38 9.99e-6 Obesity-related traits; TGCT cis rs4665809 1.000 rs11126364 chr2:26314515 A/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg15691649 chr6:25882328 NA 0.4 4.65 0.39 8.27e-6 Intelligence (multi-trait analysis); TGCT cis rs2455799 0.559 rs1900614 chr3:15912127 G/A cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs2898681 0.519 rs76606067 chr4:53728221 G/T cg00791764 chr4:53727839 RASL11B 0.54 4.58 0.38 1.1e-5 Optic nerve measurement (cup area); TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg10802521 chr3:52805072 NEK4 -0.78 -9.89 -0.66 2.32e-17 Bipolar disorder; TGCT trans rs1005277 0.528 rs2057228 chr10:38515766 T/C cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs2180341 0.924 rs9285459 chr6:127631113 T/C cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs2839186 0.708 rs17183123 chr21:47671961 G/C cg05896524 chr21:47604654 C21orf56 0.43 4.76 0.39 5.35e-6 Testicular germ cell tumor; TGCT cis rs7567389 0.677 rs72848616 chr2:128135097 T/C cg09760422 chr2:128146352 NA 0.34 4.52 0.38 1.41e-5 Self-rated health; TGCT cis rs12681287 0.752 rs6985427 chr8:87302745 C/T cg27223183 chr8:87520930 FAM82B -0.83 -5.97 -0.47 2.36e-8 Caudate activity during reward; TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs9906944 0.933 rs9906710 chr17:47091283 C/A cg20966754 chr17:47091339 IGF2BP1 -0.43 -4.96 -0.41 2.27e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs62244186 0.659 rs12108134 chr3:44543030 A/G cg15687855 chr3:44754131 ZNF502 0.44 5.16 0.42 9.48e-7 Depressive symptoms; TGCT cis rs2013441 1.000 rs2058971 chr17:20219508 T/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs12908161 1.000 rs12905057 chr15:85210765 A/G cg17173187 chr15:85201210 NMB 0.59 6.49 0.5 1.81e-9 Schizophrenia; TGCT cis rs9911578 1.000 rs9911578 chr17:56953147 C/T cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs5769707 0.681 rs4824068 chr22:50024801 G/A cg05373962 chr22:49881684 NA -0.31 -5.37 -0.43 3.8e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2486288 0.656 rs11629858 chr15:45547114 T/C cg26924012 chr15:45694286 SPATA5L1 -0.7 -6.77 -0.52 4.55e-10 Glomerular filtration rate; TGCT cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs9443645 0.901 rs1567167 chr6:79553827 C/T cg09184832 chr6:79620586 NA -0.47 -5.23 -0.43 6.94e-7 Intelligence (multi-trait analysis); TGCT cis rs9952991 0.566 rs7241016 chr18:12880206 A/G cg23598886 chr18:12777645 NA -0.5 -4.47 -0.37 1.73e-5 Inflammatory skin disease; TGCT cis rs11098499 0.754 rs7672372 chr4:120248406 A/G cg09307838 chr4:120376055 NA 0.61 5.92 0.47 3e-8 Corneal astigmatism; TGCT cis rs9388451 1.000 rs9388451 chr6:126090377 A/G cg10911889 chr6:126070802 HEY2 0.52 5.25 0.43 6.27e-7 Brugada syndrome; TGCT cis rs9457247 0.565 rs12178491 chr6:167512474 C/T cg07741184 chr6:167504864 NA 0.28 5.6 0.45 1.33e-7 Crohn's disease; TGCT cis rs6754311 0.513 rs1438304 chr2:136503157 A/G cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Mosquito bite size; TGCT cis rs909674 0.690 rs1972280 chr22:39831986 T/A cg02038168 chr22:39784481 NA -0.74 -5.67 -0.45 9.63e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9457247 0.508 rs6918286 chr6:167505829 C/T cg07741184 chr6:167504864 NA 0.27 5.25 0.43 6.4e-7 Crohn's disease; TGCT cis rs1467026 0.584 rs9865381 chr3:12801685 C/T cg05775895 chr3:12838266 CAND2 0.7 7.16 0.54 6.26e-11 P wave duration; TGCT cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg03517284 chr6:25882590 NA -0.52 -5.27 -0.43 5.77e-7 Blood metabolite levels; TGCT cis rs9388451 0.807 rs1269175 chr6:126040435 A/G cg10911889 chr6:126070802 HEY2 -0.53 -5.03 -0.41 1.68e-6 Brugada syndrome; TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg22166914 chr1:53195759 ZYG11B -0.39 -6.42 -0.5 2.6e-9 Monocyte count; TGCT cis rs11190604 0.607 rs12220970 chr10:102175269 G/A cg16342193 chr10:102329863 NA -0.41 -5.14 -0.42 1.04e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs72945132 0.882 rs12099016 chr11:70195161 C/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs11098499 0.863 rs6534141 chr4:120485223 A/T cg09307838 chr4:120376055 NA 0.74 7.34 0.55 2.49e-11 Corneal astigmatism; TGCT cis rs1005277 0.505 rs13503 chr10:38239843 C/A cg13531842 chr10:38383804 ZNF37A 0.39 4.58 0.38 1.12e-5 Extrinsic epigenetic age acceleration; TGCT cis rs3806843 0.966 rs7710380 chr5:140156264 T/C cg19875535 chr5:140030758 IK 0.37 6.23 0.49 6.53e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs910187 0.678 rs6122561 chr20:45813809 A/G cg27589058 chr20:45804311 EYA2 -0.36 -7.95 -0.58 9.85e-13 Migraine; TGCT cis rs1023500 0.551 rs61665536 chr22:42512613 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Schizophrenia; TGCT cis rs854765 0.583 rs8073001 chr17:17831716 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.74 -0.57 2.94e-12 Total body bone mineral density; TGCT cis rs3849570 1.000 rs7638516 chr3:81826249 A/C cg07356753 chr3:81810745 GBE1 -0.7 -5.94 -0.47 2.67e-8 Waist circumference;Body mass index; TGCT cis rs492146 0.691 rs316138 chr6:52846419 T/C cg06706454 chr6:52930286 FBXO9 -0.53 -4.95 -0.41 2.36e-6 Epilepsy (remission after treatment); TGCT cis rs3858526 0.676 rs10838752 chr11:5887243 A/G cg13902645 chr11:5959945 NA -0.43 -4.61 -0.38 9.96e-6 DNA methylation (variation); TGCT cis rs2639990 0.744 rs640261 chr18:72905808 C/T cg18449964 chr18:72917101 ZADH2 0.92 6.07 0.48 1.46e-8 Vascular endothelial growth factor levels; TGCT cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg04632378 chr13:21900426 NA 0.4 4.92 0.4 2.68e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs17376456 0.597 rs7708175 chr5:93381182 A/G cg25358565 chr5:93447407 FAM172A -0.62 -5.79 -0.46 5.34e-8 Diabetic retinopathy; TGCT cis rs2439831 0.867 rs3809481 chr15:43662829 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.91 5.92 0.47 3e-8 Lung cancer in ever smokers; TGCT cis rs67311347 1.000 rs34762643 chr3:40475433 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs4460629 0.521 rs12039316 chr1:155073221 C/T cg23973274 chr1:155060172 NA -0.25 -4.5 -0.38 1.51e-5 Serum magnesium levels; TGCT cis rs854765 0.647 rs854790 chr17:18028318 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.34 0.55 2.42e-11 Total body bone mineral density; TGCT cis rs7618915 0.798 rs353547 chr3:52268866 A/G cg07507251 chr3:52567010 NT5DC2 -0.42 -5.74 -0.46 6.75e-8 Bipolar disorder; TGCT cis rs612683 0.602 rs2030048 chr1:101006577 C/T cg06223162 chr1:101003688 GPR88 -0.34 -6.06 -0.48 1.5e-8 Breast cancer; TGCT cis rs11585357 0.895 rs34324150 chr1:17632464 C/G cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs514406 0.505 rs6703127 chr1:53180565 C/T cg16325326 chr1:53192061 ZYG11B 0.86 12.38 0.74 2.09e-23 Monocyte count; TGCT cis rs317865 0.737 rs73234629 chr4:16169776 G/A cg04764131 chr4:16228633 TAPT1;FLJ39653 0.78 4.98 0.41 2.08e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs826838 1.000 rs826888 chr12:39104719 C/G cg26384229 chr12:38710491 ALG10B -0.88 -8.27 -0.6 1.77e-13 Heart rate; TGCT cis rs7819412 0.805 rs4333549 chr8:10979561 C/G cg21775007 chr8:11205619 TDH -0.52 -5.03 -0.41 1.66e-6 Triglycerides; TGCT cis rs317689 0.690 rs595348 chr12:69638610 T/C cg14784868 chr12:69753453 YEATS4 0.54 4.5 0.37 1.56e-5 Response to diuretic therapy; TGCT cis rs921968 0.643 rs471846 chr2:219432237 C/T cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs12530845 1.000 rs6979391 chr7:135328873 C/T cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg06634786 chr22:41940651 POLR3H -0.72 -6.61 -0.51 1.02e-9 Vitiligo; TGCT cis rs734999 0.545 rs10910106 chr1:2538886 G/T cg18854424 chr1:2615690 NA 0.41 4.58 0.38 1.13e-5 Ulcerative colitis; TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs922182 0.579 rs13329518 chr15:64241080 T/C cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.33e-10 Blood protein levels; TGCT cis rs939658 0.805 rs11638625 chr15:79434787 T/G cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs350251 0.868 rs350231 chr16:12186376 T/G cg01574788 chr16:12184133 SNX29 0.4 5.24 0.43 6.58e-7 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs11707673 chr3:40450604 C/A cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs1062177 0.906 rs2964573 chr5:151160122 A/T cg00977110 chr5:151150581 G3BP1 0.4 4.57 0.38 1.16e-5 Preschool internalizing problems; TGCT trans rs11088226 0.681 rs2833897 chr21:33931792 T/C cg09050820 chr6:167586206 TCP10L2 0.78 6.96 0.53 1.71e-10 Gastritis; TGCT cis rs7662987 0.517 rs1154406 chr4:100008494 T/C cg12011299 chr4:100065546 ADH4 0.42 4.87 0.4 3.38e-6 Smoking initiation; TGCT cis rs763121 0.853 rs138702 chr22:39132601 A/T cg06022373 chr22:39101656 GTPBP1 -0.81 -7.64 -0.57 5.08e-12 Menopause (age at onset); TGCT cis rs3820068 0.603 rs6696286 chr1:15968770 C/T cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.25e-13 Systolic blood pressure; TGCT cis rs6426558 0.537 rs7512409 chr1:227484038 A/G cg10327440 chr1:227177885 CDC42BPA -0.56 -6.62 -0.51 9.6e-10 Neutrophil percentage of white cells; TGCT cis rs13256369 0.950 rs13248096 chr8:8577476 C/T cg17143192 chr8:8559678 CLDN23 0.61 5.74 0.46 6.82e-8 Obesity-related traits; TGCT cis rs7726839 0.507 rs56282020 chr5:596701 T/C cg20362242 chr5:692897 TPPP 0.53 4.62 0.38 9.56e-6 Obesity-related traits; TGCT cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg15659132 chr6:26577336 NA 0.87 10.72 0.69 2.19e-19 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs114584210 chr4:119773363 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs2180341 0.961 rs910720 chr6:127619070 T/C cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg04234412 chr22:24373322 LOC391322 -0.92 -11.06 -0.7 3.33e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11190604 0.767 rs10883485 chr10:102174805 G/C cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.5e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9611519 0.590 rs4821980 chr22:41415479 C/G cg13695892 chr22:41940480 POLR3H -0.54 -5.1 -0.42 1.21e-6 Neuroticism; TGCT cis rs1570884 0.767 rs7996207 chr13:50122681 G/A cg08779649 chr13:50194554 NA 0.3 4.75 0.39 5.58e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs2594989 0.943 rs2454504 chr3:11498423 G/A cg26283222 chr3:11613257 VGLL4 -0.21 -4.6 -0.38 1.01e-5 Circulating chemerin levels; TGCT cis rs7805747 0.961 rs10253736 chr7:151415256 C/T cg17611936 chr7:151411526 PRKAG2 0.54 6.72 0.52 5.9e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs6952808 0.609 rs10274300 chr7:1950405 C/G cg04267008 chr7:1944627 MAD1L1 -0.35 -4.44 -0.37 1.95e-5 Bipolar disorder and schizophrenia; TGCT cis rs7586879 0.639 rs6545776 chr2:25099357 A/C cg15423357 chr2:25149977 NA 0.5 4.75 0.39 5.63e-6 Body mass index; TGCT cis rs10206020 0.885 rs6720923 chr2:1574197 T/C cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs2243480 1.000 rs34815098 chr7:65292254 A/C cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs11792861 0.926 rs11788904 chr9:111865052 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.48 0.37 1.66e-5 Menarche (age at onset); TGCT cis rs924607 1.000 rs4045344 chr5:595870 G/T cg18765565 chr5:669397 TPPP -0.58 -6.23 -0.49 6.51e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg16325326 chr1:53192061 ZYG11B 0.6 6.77 0.52 4.62e-10 Monocyte count; TGCT cis rs1018836 0.828 rs9297870 chr8:91570691 C/G cg16814680 chr8:91681699 NA -0.8 -8.26 -0.6 1.85e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2760061 0.626 rs672977 chr1:228120288 A/C cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT trans rs77457752 0.525 rs10121526 chr9:13898615 G/A cg23609682 chr1:3070786 PRDM16 0.5 6.79 0.52 4.09e-10 Breast cancer; TGCT cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs986417 1.000 rs10143118 chr14:61066043 G/A cg27398547 chr14:60952738 C14orf39 1.48 10.51 0.69 7.42e-19 Gut microbiota (bacterial taxa); TGCT cis rs3806843 0.612 rs246075 chr5:140300557 T/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.42 -5.21 -0.42 7.71e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs4824093 0.610 rs58671506 chr22:50288983 G/A cg09872104 chr7:134855509 C7orf49 -0.96 -7.87 -0.58 1.49e-12 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs2439831 0.850 rs8023458 chr15:44080939 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.01 0.47 1.91e-8 Lung cancer in ever smokers; TGCT cis rs4631830 0.832 rs1585378 chr10:51523213 A/T cg10326726 chr10:51549505 MSMB -0.27 -5.42 -0.44 3.01e-7 Prostate-specific antigen levels; TGCT cis rs2072499 0.750 rs2241109 chr1:156173082 C/T cg25208724 chr1:156163844 SLC25A44 1.02 9.51 0.65 2e-16 Testicular germ cell tumor; TGCT cis rs1372520 0.684 rs1811442 chr4:90747751 C/T cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs8141529 0.509 rs6005927 chr22:29255884 A/G cg02153584 chr22:29168773 CCDC117 0.6 4.77 0.39 4.98e-6 Lymphocyte counts; TGCT cis rs769267 0.930 rs1047361 chr19:19606634 G/A cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs7296418 0.961 rs11613937 chr12:123520071 C/T cg00376283 chr12:123451042 ABCB9 0.87 8.22 0.59 2.34e-13 Platelet count; TGCT cis rs7772486 0.875 rs9403763 chr6:146357655 A/G cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs28465658 chr4:99035866 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.623 rs11506668 chr9:5252789 C/T cg02405213 chr9:5042618 JAK2 -0.7 -8.27 -0.6 1.78e-13 Pediatric autoimmune diseases; TGCT trans rs7618501 0.699 rs11130224 chr3:49936910 T/A cg21659725 chr3:3221576 CRBN 0.77 9.15 0.63 1.42e-15 Intelligence (multi-trait analysis); TGCT cis rs7914558 0.966 rs10883817 chr10:104755431 C/T cg15744005 chr10:104629667 AS3MT -0.4 -4.89 -0.4 3.06e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2880765 0.835 rs900573 chr15:86037993 G/T cg13263323 chr15:86062960 AKAP13 0.21 4.52 0.38 1.44e-5 Coronary artery disease; TGCT cis rs3924048 0.574 rs12096486 chr1:12616911 T/C cg00291366 chr1:12616550 NA 0.33 5.14 0.42 1.05e-6 Optic cup area; TGCT cis rs1862618 0.853 rs2113078 chr5:56087190 C/T cg18230493 chr5:56204884 C5orf35 -0.74 -5.18 -0.42 8.84e-7 Initial pursuit acceleration; TGCT cis rs2840044 1.000 rs225251 chr17:33951228 A/C cg05299278 chr17:33885742 SLFN14 0.22 4.93 0.4 2.63e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs4654899 0.582 rs4654729 chr1:21224253 T/C cg01072550 chr1:21505969 NA 0.55 8.92 0.62 5.21e-15 Superior frontal gyrus grey matter volume; TGCT cis rs6815814 0.861 rs7658651 chr4:38786002 A/C cg02016764 chr4:38805732 TLR1 -0.27 -4.46 -0.37 1.78e-5 Breast cancer; TGCT cis rs9357506 0.967 rs4714923 chr6:46304002 A/T cg21115430 chr6:46460003 NA -0.26 -5.04 -0.41 1.58e-6 Body mass index; TGCT cis rs308403 0.568 rs13120869 chr4:123646152 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.7 6.41 0.5 2.8e-9 Blood protein levels; TGCT cis rs9457247 1.000 rs2149085 chr6:167371110 T/C cg23791538 chr6:167370224 RNASET2 0.51 4.98 0.41 2.06e-6 Crohn's disease; TGCT cis rs13242816 1.000 rs55803834 chr7:116103141 C/T cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT trans rs208520 0.690 rs4710564 chr6:66823478 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.94 7.71 0.57 3.49e-12 Exhaled nitric oxide output; TGCT cis rs4665809 1.000 rs1371553 chr2:26262948 G/A cg25036284 chr2:26402008 FAM59B -0.56 -4.85 -0.4 3.62e-6 Gut microbiome composition (summer); TGCT cis rs7666738 0.546 rs1456207 chr4:98676911 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.29 0.43 5.45e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.59 -5.89 -0.47 3.47e-8 Bipolar disorder; TGCT cis rs3617 0.652 rs7630552 chr3:52891570 G/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.49 -4.58 -0.38 1.09e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7726839 0.540 rs56325086 chr5:640728 G/A cg20362242 chr5:692897 TPPP 0.49 4.45 0.37 1.89e-5 Obesity-related traits; TGCT cis rs362272 0.505 rs10155132 chr4:3369500 A/G cg22655196 chr4:3374909 RGS12 0.22 4.56 0.38 1.23e-5 Serum sulfate level; TGCT cis rs9467773 1.000 rs10946834 chr6:26533664 G/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg16145915 chr7:1198662 ZFAND2A 0.56 7.23 0.54 4.47e-11 Longevity;Endometriosis; TGCT cis rs6570726 0.935 rs390252 chr6:145856896 A/G cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2115630 0.691 rs61322921 chr15:85163638 T/C cg12501888 chr15:85177176 SCAND2 -0.51 -4.74 -0.39 5.88e-6 P wave terminal force; TGCT cis rs1008375 0.931 rs10008337 chr4:17593849 G/C cg16339924 chr4:17578868 LAP3 0.81 6.69 0.52 6.75e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2120019 0.786 rs12911421 chr15:75287822 C/A cg17294928 chr15:75287854 SCAMP5 0.98 9.45 0.65 2.65e-16 Blood trace element (Zn levels); TGCT cis rs2115630 1.000 rs2879828 chr15:85361977 G/T cg17173187 chr15:85201210 NMB -0.4 -4.9 -0.4 2.89e-6 P wave terminal force; TGCT cis rs593982 0.920 rs4930298 chr11:65448108 T/A cg08755490 chr11:65554678 OVOL1 -1.21 -6.67 -0.51 7.71e-10 Atopic dermatitis; TGCT cis rs11690935 0.851 rs9808259 chr2:172648974 C/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT trans rs1814175 0.715 rs11040586 chr11:49858432 T/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT trans rs7613875 0.537 rs6446195 chr3:50070853 A/G cg21659725 chr3:3221576 CRBN -0.67 -7.53 -0.56 9.05e-12 Body mass index; TGCT cis rs12682352 0.652 rs1567398 chr8:8726804 A/C cg06636001 chr8:8085503 FLJ10661 -0.7 -6.63 -0.51 9.32e-10 Neuroticism; TGCT cis rs11948739 0.539 rs10045319 chr5:130250710 G/A cg08523029 chr5:130500466 HINT1 0.57 4.62 0.38 9.66e-6 Pediatric bone mineral content (hip); TGCT cis rs12682352 0.602 rs6988939 chr8:8666916 C/T cg15556689 chr8:8085844 FLJ10661 0.59 5.03 0.41 1.69e-6 Neuroticism; TGCT cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg25767906 chr1:53392781 SCP2 0.61 7.44 0.56 1.48e-11 Monocyte count; TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs1635 0.826 rs4711167 chr6:28294888 C/T cg15743358 chr6:28303923 ZNF323 1.32 6.0 0.47 2.05e-8 Schizophrenia; TGCT cis rs7647973 1.000 rs10865956 chr3:49581559 C/A cg07636037 chr3:49044803 WDR6 0.65 5.35 0.43 4.01e-7 Menarche (age at onset); TGCT cis rs2637266 0.935 rs6480822 chr10:78354092 A/C cg18941641 chr10:78392320 NA 0.41 4.86 0.4 3.51e-6 Pulmonary function; TGCT cis rs9296092 0.517 rs3912041 chr6:33521271 T/C cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.89 0.4 3e-6 Platelet count; TGCT cis rs11098499 0.754 rs10213554 chr4:120260785 A/G cg09307838 chr4:120376055 NA -0.61 -5.95 -0.47 2.56e-8 Corneal astigmatism; TGCT cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs10479542 0.929 rs10074573 chr5:178976966 C/T cg14820908 chr5:178986412 RUFY1 -0.44 -4.44 -0.37 1.96e-5 Lung cancer; TGCT cis rs6693567 0.545 rs9436009 chr1:150459426 T/A cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Migraine; TGCT cis rs3026101 0.671 rs1071705 chr17:5290033 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.57 0.38 1.16e-5 Body mass index; TGCT cis rs7772486 0.875 rs865913 chr6:146308874 C/T cg13319975 chr6:146136371 FBXO30 -0.53 -4.68 -0.39 7.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11719291 0.504 rs71324924 chr3:48865444 G/A cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 Cognitive function; TGCT cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs42648 0.748 rs10227385 chr7:89890368 C/A cg25739043 chr7:89950458 NA -0.63 -6.12 -0.48 1.15e-8 Homocysteine levels; TGCT cis rs7439150 0.954 rs2227424 chr4:155492720 C/G cg22130008 chr4:155548532 NA -0.51 -6.87 -0.52 2.79e-10 Fibrinogen levels; TGCT cis rs939574 0.512 rs6730612 chr2:220146196 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.78 5.54 0.45 1.71e-7 Platelet distribution width; TGCT cis rs2032447 0.613 rs6456708 chr6:26032847 G/C cg03264133 chr6:25882463 NA -0.46 -4.59 -0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT trans rs561341 0.739 rs4795663 chr17:30214542 T/C cg20587970 chr11:113659929 NA 0.59 8.85 0.62 7.64e-15 Hip circumference adjusted for BMI; TGCT cis rs7698623 0.717 rs4693893 chr4:88797765 A/G cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs854765 0.693 rs9907246 chr17:17770965 T/C cg09796270 chr17:17721594 SREBF1 -0.28 -5.62 -0.45 1.17e-7 Total body bone mineral density; TGCT cis rs6582630 0.537 rs1949611 chr12:38373092 C/T cg26384229 chr12:38710491 ALG10B -0.77 -6.93 -0.53 2.05e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs9389248 0.500 rs116273677 chr6:135339135 A/C cg24558204 chr6:135376177 HBS1L 0.48 4.77 0.39 5.14e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs736408 0.812 rs2071507 chr3:52826707 G/A cg10802521 chr3:52805072 NEK4 -0.64 -7.42 -0.55 1.65e-11 Bipolar disorder; TGCT cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs6840360 0.904 rs6813516 chr4:152594407 C/G cg22705602 chr4:152727874 NA -0.26 -4.46 -0.37 1.81e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg08280861 chr8:58055591 NA 0.36 4.98 0.41 2.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs9296661 0.832 rs6458787 chr6:51667058 A/G cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs11648796 0.765 rs2003832 chr16:769538 G/A cg27144592 chr16:783916 NARFL 0.42 5.76 0.46 6.37e-8 Height; TGCT cis rs9926296 0.585 rs4785595 chr16:89835521 C/T cg26513180 chr16:89883248 FANCA -1.01 -13.53 -0.77 3.53e-26 Vitiligo; TGCT cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.43 -0.44 2.89e-7 Coronary artery disease; TGCT cis rs7582180 0.663 rs6542944 chr2:100988038 T/C cg08017756 chr2:100939284 LONRF2 -0.31 -5.14 -0.42 1.06e-6 Intelligence (multi-trait analysis); TGCT cis rs7216064 1.000 rs7223813 chr17:65945840 A/G cg12091567 chr17:66097778 LOC651250 -0.82 -6.2 -0.49 7.54e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2688608 0.592 rs3849967 chr10:75483366 C/T cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs2243480 1.000 rs67536397 chr7:65947917 G/A cg07424592 chr7:64974309 NA 1.29 8.01 0.58 7.16e-13 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs3885839 chr7:65290403 G/T cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT trans rs2727020 0.724 rs4109837 chr11:49372051 A/T cg03929089 chr4:120376271 NA -0.67 -6.99 -0.53 1.52e-10 Coronary artery disease; TGCT cis rs904251 0.864 rs2797801 chr6:37487161 A/G cg01843034 chr6:37503916 NA -0.52 -6.28 -0.49 5.17e-9 Cognitive performance; TGCT cis rs7572733 0.555 rs6434953 chr2:198929693 A/G cg00792783 chr2:198669748 PLCL1 0.58 5.11 0.42 1.21e-6 Dermatomyositis; TGCT cis rs1933488 1.000 rs6927516 chr6:153441831 G/A cg24028809 chr6:153414101 RGS17 0.2 4.5 0.38 1.51e-5 Prostate cancer; TGCT trans rs7726839 0.540 rs72703087 chr5:598029 C/T cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs17376456 1.000 rs34854140 chr5:93538169 G/A cg25358565 chr5:93447407 FAM172A 0.93 7.91 0.58 1.22e-12 Diabetic retinopathy; TGCT cis rs2153535 0.580 rs7743418 chr6:8438128 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg23982607 chr1:1823379 GNB1 -0.54 -8.17 -0.59 3.1e-13 Body mass index; TGCT cis rs782590 0.967 rs35504023 chr2:55806503 C/T cg03859395 chr2:55845619 SMEK2 -0.92 -11.39 -0.72 5.08e-21 Metabolic syndrome; TGCT cis rs9611565 0.512 rs5758450 chr22:42141640 G/A cg03806693 chr22:41940476 POLR3H 1.02 10.5 0.69 7.8e-19 Vitiligo; TGCT cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg26118208 chr10:134322334 NA 0.25 4.65 0.39 8.37e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs1005277 0.579 rs176886 chr10:38403974 C/T cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.33 0.43 4.52e-7 Platelet count; TGCT cis rs610932 0.517 rs474123 chr11:59901422 C/A cg18570331 chr11:60101691 MS4A6E -0.51 -4.58 -0.38 1.1e-5 Alzheimer's disease; TGCT cis rs7937682 0.632 rs7128862 chr11:111755435 C/T cg09085632 chr11:111637200 PPP2R1B 0.84 7.27 0.55 3.45e-11 Primary sclerosing cholangitis; TGCT cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg05738196 chr6:26577821 NA -0.86 -10.85 -0.7 1.11e-19 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.641 rs6979368 chr7:107089009 C/G cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs7677751 0.806 rs7689569 chr4:55096398 G/A cg17187183 chr4:55093834 PDGFRA 0.55 7.05 0.54 1.08e-10 Corneal astigmatism; TGCT cis rs9916302 0.706 rs9899069 chr17:37540772 A/G cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs1570884 0.857 rs9535263 chr13:50137363 T/A cg08779649 chr13:50194554 NA 0.3 4.45 0.37 1.92e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs9549367 0.713 rs3024769 chr13:113825601 A/C cg18105134 chr13:113819100 PROZ 0.47 8.34 0.6 1.23e-13 Platelet distribution width; TGCT cis rs2236918 0.710 rs1635510 chr1:242027500 G/T cg04158730 chr1:242011433 EXO1 0.56 5.2 0.42 8.05e-7 Menopause (age at onset); TGCT cis rs6967414 0.786 rs9639026 chr7:6746736 A/G cg09896999 chr7:6746977 ZNF12 -0.59 -6.48 -0.5 1.96e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs2921036 0.503 rs7817832 chr8:8380821 T/C cg06636001 chr8:8085503 FLJ10661 0.82 6.36 0.5 3.49e-9 Neuroticism; TGCT cis rs4654899 0.865 rs6673455 chr1:21361048 T/C cg01072550 chr1:21505969 NA -0.47 -7.02 -0.53 1.28e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4466137 0.794 rs6869296 chr5:83007333 C/G cg16102102 chr5:83017553 HAPLN1 0.8 8.59 0.61 3.08e-14 Prostate cancer; TGCT cis rs1505368 0.789 rs13419353 chr2:213271459 A/T cg16329650 chr2:213403929 ERBB4 -0.59 -5.79 -0.46 5.49e-8 Symmetrical dimethylarginine levels; TGCT cis rs4722166 0.630 rs10950916 chr7:22799667 C/T cg23864514 chr7:22882512 NA 0.21 4.46 0.37 1.83e-5 Lung cancer; TGCT cis rs7845219 0.544 rs10956932 chr8:95948202 C/T cg09323728 chr8:95962352 TP53INP1 0.39 4.6 0.38 1.02e-5 Type 2 diabetes; TGCT cis rs4294134 0.545 rs11534080 chr7:135247528 C/T cg08396481 chr7:135194601 CNOT4 -0.58 -4.68 -0.39 7.53e-6 Paget's disease; TGCT cis rs9926296 0.682 rs258328 chr16:89730314 C/T cg26513180 chr16:89883248 FANCA -0.67 -6.37 -0.5 3.32e-9 Vitiligo; TGCT cis rs875971 0.964 rs12668936 chr7:65914404 C/T cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs4746818 0.901 rs4746816 chr10:70874866 G/T cg11621586 chr10:70884670 VPS26A 1.14 7.94 0.58 1.03e-12 Left atrial antero-posterior diameter; TGCT cis rs7614311 0.681 rs6796317 chr3:63927739 A/G cg22134162 chr3:63841271 THOC7 -0.49 -6.18 -0.49 8.42e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs7552404 0.731 rs17650138 chr1:76398887 C/T cg03433033 chr1:76189801 ACADM -0.84 -7.75 -0.57 2.91e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2115630 0.936 rs11073663 chr15:85260268 A/G cg12863693 chr15:85201151 NMB -0.33 -4.52 -0.38 1.41e-5 P wave terminal force; TGCT cis rs2180341 0.920 rs9398836 chr6:127576497 T/G cg27446573 chr6:127587934 RNF146 1.07 9.73 0.66 5.7e-17 Breast cancer; TGCT cis rs1577917 0.958 rs34622605 chr6:86456519 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.53 -0.44 1.8e-7 Response to antipsychotic treatment; TGCT cis rs10504229 1.000 rs58608483 chr8:58195269 T/G cg24829409 chr8:58192753 C8orf71 -0.49 -4.58 -0.38 1.11e-5 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.966 rs2227890 chr20:25260931 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg17054783 chr10:134559939 INPP5A 0.23 4.48 0.37 1.66e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17102423 0.723 rs55658675 chr14:65554638 C/T cg11161011 chr14:65562177 MAX -0.55 -7.7 -0.57 3.74e-12 Obesity-related traits; TGCT cis rs7829975 0.593 rs2921077 chr8:8304502 C/T cg15556689 chr8:8085844 FLJ10661 0.72 7.19 0.54 5.32e-11 Mood instability; TGCT cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg21724239 chr8:58056113 NA 0.39 5.28 0.43 5.67e-7 Developmental language disorder (linguistic errors); TGCT cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs3733585 0.699 rs7686538 chr4:9948077 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.45 -0.5 2.22e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs1568079 0.516 rs2361382 chr10:125220299 C/G cg02936953 chr10:124639892 FAM24B;LOC399815 -0.35 -5.29 -0.43 5.31e-7 Body mass index; TGCT cis rs9921222 0.500 rs8046256 chr16:393948 C/T cg00101154 chr16:420108 MRPL28 -0.52 -5.01 -0.41 1.85e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs7824557 0.579 rs10098322 chr8:11196295 C/G cg21775007 chr8:11205619 TDH 0.7 6.85 0.52 3.08e-10 Retinal vascular caliber; TGCT cis rs514406 0.505 rs431427 chr1:53179094 C/A cg24675658 chr1:53192096 ZYG11B -0.79 -9.71 -0.66 6.32e-17 Monocyte count; TGCT trans rs2727020 0.729 rs6485965 chr11:49166730 C/T cg03929089 chr4:120376271 NA 0.69 7.69 0.57 3.93e-12 Coronary artery disease; TGCT cis rs11971779 0.793 rs11764426 chr7:139024050 C/G cg07862535 chr7:139043722 LUC7L2 0.74 5.9 0.47 3.21e-8 Diisocyanate-induced asthma; TGCT cis rs17030434 0.834 rs11734251 chr4:154732218 C/T cg14289246 chr4:154710475 SFRP2 -0.91 -7.57 -0.56 7.44e-12 Electrocardiographic conduction measures; TGCT cis rs1483890 0.723 rs13061189 chr3:69411453 T/C cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs9814567 1.000 rs62269547 chr3:134214042 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3796352 1.000 rs61172708 chr3:52996052 T/G cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs727505 1.000 rs1541418 chr7:124448672 A/G cg23710748 chr7:124431027 NA -0.28 -4.9 -0.4 2.92e-6 Lewy body disease; TGCT cis rs6964587 0.626 rs4422709 chr7:91510968 A/G cg17063962 chr7:91808500 NA -0.75 -7.02 -0.53 1.25e-10 Breast cancer; TGCT cis rs4665809 1.000 rs2384323 chr2:26306473 C/T cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg13770153 chr20:60521292 NA -0.54 -7.57 -0.56 7.23e-12 Body mass index; TGCT cis rs7979473 1 rs7979473 chr12:121420260 A/G cg02403541 chr12:121454288 C12orf43 -0.52 -4.48 -0.37 1.68e-5 C-reactive protein; TGCT cis rs6540559 0.546 rs735694 chr1:210034029 T/C cg22029157 chr1:209979665 IRF6 0.79 5.78 0.46 5.6e-8 Cleft lip with or without cleft palate; TGCT cis rs1005277 0.541 rs1740741 chr10:38515334 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs35160687 0.829 rs13017143 chr2:86466549 C/T cg03171300 chr2:86307199 POLR1A -0.32 -5.28 -0.43 5.56e-7 Night sleep phenotypes; TGCT cis rs2153535 0.563 rs1796688 chr6:8536423 A/T cg23788917 chr6:8435910 SLC35B3 0.67 5.94 0.47 2.69e-8 Motion sickness; TGCT cis rs763014 0.966 rs35642938 chr16:642249 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.25 -0.6 2.01e-13 Height; TGCT cis rs8180040 0.620 rs749511 chr3:47035735 A/C cg27129171 chr3:47204927 SETD2 -0.7 -8.34 -0.6 1.21e-13 Colorectal cancer; TGCT cis rs6089829 0.962 rs4809456 chr20:61660849 C/A cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs12497850 0.931 rs62262517 chr3:49134914 T/G cg05785598 chr3:49045655 WDR6 0.36 4.8 0.4 4.48e-6 Parkinson's disease; TGCT cis rs12519773 0.501 rs4321736 chr5:92533363 C/T cg04854328 chr5:92914828 FLJ42709 -0.3 -4.58 -0.38 1.12e-5 Migraine; TGCT cis rs763121 0.819 rs5757169 chr22:39003495 G/A cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT trans rs7618501 0.573 rs2624824 chr3:50088266 T/C cg21659725 chr3:3221576 CRBN -0.73 -8.48 -0.61 5.64e-14 Intelligence (multi-trait analysis); TGCT cis rs554111 0.637 rs604659 chr1:21043913 T/C cg08890418 chr1:21044141 KIF17 0.51 5.57 0.45 1.51e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs868036 0.681 rs13329582 chr15:68104608 G/C cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs17376456 0.825 rs34592268 chr5:93232751 G/C cg25358565 chr5:93447407 FAM172A 1.01 8.13 0.59 3.77e-13 Diabetic retinopathy; TGCT cis rs950169 0.840 rs4842854 chr15:84942339 T/G cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs5750830 0.594 rs5757648 chr22:39775156 G/A cg02038168 chr22:39784481 NA -0.64 -5.48 -0.44 2.32e-7 Intelligence (multi-trait analysis); TGCT trans rs561341 1.000 rs535151 chr17:30317405 C/T cg20587970 chr11:113659929 NA -0.96 -12.16 -0.74 6.93e-23 Hip circumference adjusted for BMI; TGCT cis rs769267 0.899 rs67720221 chr19:19440864 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.69 -6.21 -0.49 7.3e-9 Tonsillectomy; TGCT cis rs2880765 0.835 rs7163958 chr15:86045215 G/A cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs34461023 chr4:99023751 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.64 0.45 1.09e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs904251 1.000 rs10947673 chr6:37445079 C/T cg25019722 chr6:37503610 NA -0.47 -6.26 -0.49 5.69e-9 Cognitive performance; TGCT cis rs2692947 0.795 rs2252697 chr2:96778190 G/C cg23100626 chr2:96804247 ASTL -0.39 -4.68 -0.39 7.5e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7552404 0.727 rs1146653 chr1:76280438 A/G cg10523679 chr1:76189770 ACADM 0.74 7.2 0.54 5.04e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3772130 1.000 rs33988592 chr3:121415610 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.85 0.4 3.66e-6 Cognitive performance; TGCT cis rs617219 0.597 rs10474581 chr5:78578884 G/A cg23514016 chr5:78407564 BHMT -0.34 -5.09 -0.42 1.29e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4919694 0.572 rs12255989 chr10:104867206 C/T cg04362960 chr10:104952993 NT5C2 0.99 7.01 0.53 1.36e-10 Arsenic metabolism; TGCT cis rs1008375 1.000 rs4698641 chr4:17642630 C/T cg10189774 chr4:17578691 LAP3 0.55 4.9 0.4 2.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6912958 0.535 rs242283 chr6:88030931 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.71 7.21 0.54 4.9e-11 Monocyte percentage of white cells; TGCT cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.97e-9 Intelligence (multi-trait analysis); TGCT cis rs2842992 0.958 rs2758318 chr6:160069637 C/G cg11366901 chr6:160182831 ACAT2 0.92 6.27 0.49 5.5e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg02353165 chr6:42928485 GNMT 0.94 9.36 0.64 4.5e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7639513 0.737 rs13070228 chr3:12706914 G/A cg23032965 chr3:12705835 RAF1 0.77 8.55 0.61 3.81e-14 Itch intensity from mosquito bite; TGCT cis rs9653442 0.564 rs2309756 chr2:100780269 G/C cg07810366 chr2:100720526 AFF3 -0.36 -5.26 -0.43 6.14e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs769267 0.965 rs10419245 chr19:19383755 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.01 0.41 1.86e-6 Tonsillectomy; TGCT trans rs1814175 0.511 rs61905634 chr11:49819736 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs453301 0.598 rs2921383 chr8:8892221 C/T cg15556689 chr8:8085844 FLJ10661 0.76 6.87 0.52 2.8e-10 Joint mobility (Beighton score); TGCT cis rs7175404 0.591 rs57685087 chr15:94060306 G/A cg18324227 chr15:93584571 NA 0.5 4.88 0.4 3.15e-6 Attention deficit hyperactivity disorder; TGCT cis rs8177179 0.560 rs8177237 chr3:133476421 C/G cg08048268 chr3:133502702 NA -0.44 -5.22 -0.42 7.37e-7 Iron status biomarkers (transferrin levels); TGCT cis rs1799949 0.965 rs9897425 chr17:41430179 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.42 4.51 0.38 1.48e-5 Menopause (age at onset); TGCT cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg11301795 chr4:187892539 NA -0.3 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg18654377 chr3:49208889 KLHDC8B -0.37 -4.91 -0.4 2.81e-6 Menarche (age at onset); TGCT cis rs7666738 0.830 rs11725652 chr4:98878362 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.94 0.41 2.42e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9436747 0.641 rs3828039 chr1:66053556 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.68 0.39 7.45e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg10819733 chr22:24237672 NA -0.31 -4.95 -0.41 2.37e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4767364 1.000 rs7979545 chr12:112790648 T/C cg10833066 chr12:111807467 FAM109A 0.33 5.1 0.42 1.23e-6 Oral cavity and pharyngeal cancer; TGCT cis rs2197308 0.765 rs11182900 chr12:37934009 C/T cg13010199 chr12:38710504 ALG10B 0.66 5.33 0.43 4.41e-7 Morning vs. evening chronotype; TGCT cis rs11190604 1.000 rs11190578 chr10:102238953 C/T cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs62103177 0.673 rs7242867 chr18:77603270 A/T cg05926928 chr17:57297772 GDPD1 1.05 10.15 0.67 5.52e-18 Opioid sensitivity; TGCT trans rs8073060 0.586 rs72829923 chr17:34045089 T/A cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7647973 0.592 rs6774202 chr3:49687779 T/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs11578119 0.898 rs10919391 chr1:170381360 T/C cg09767346 chr1:170501363 GORAB 0.71 5.64 0.45 1.07e-7 Male-pattern baldness; TGCT cis rs9911578 0.805 rs1811202 chr17:56454435 T/G cg12560992 chr17:57184187 TRIM37 -0.71 -7.41 -0.55 1.69e-11 Intelligence (multi-trait analysis); TGCT cis rs6089584 1.000 rs6089587 chr20:60564829 C/T cg06108461 chr20:60628389 TAF4 -0.53 -7.39 -0.55 1.9e-11 Body mass index; TGCT cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.45 6.77 0.52 4.52e-10 Schizophrenia; TGCT cis rs8180040 0.739 rs4683320 chr3:47152992 C/T cg27129171 chr3:47204927 SETD2 0.76 9.9 0.66 2.25e-17 Colorectal cancer; TGCT cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs231513 0.769 rs537169 chr17:41976740 G/A cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg05896524 chr21:47604654 C21orf56 0.4 4.53 0.38 1.37e-5 Testicular germ cell tumor; TGCT cis rs9902453 1.000 rs4328498 chr17:28344276 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.55 -0.51 1.36e-9 Coffee consumption (cups per day); TGCT cis rs9926296 0.632 rs4785716 chr16:89801127 T/C cg27121462 chr16:89883253 FANCA 0.55 5.06 0.41 1.45e-6 Vitiligo; TGCT cis rs6750047 0.932 rs11124631 chr2:38274908 A/G cg07380506 chr2:38303506 CYP1B1 -0.6 -5.31 -0.43 4.92e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs875971 0.862 rs2024192 chr7:66041447 G/T cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs7666738 0.800 rs10028921 chr4:98962630 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.83e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg17345569 chr6:42928274 GNMT -0.48 -4.97 -0.41 2.22e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1153858 1.000 rs1980288 chr15:45620612 T/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.65 0.45 1.05e-7 Homoarginine levels; TGCT cis rs6569992 0.500 rs3752383 chr6:135522755 A/G cg22676075 chr6:135203613 NA 0.77 4.86 0.4 3.51e-6 Red blood cell traits; TGCT cis rs6840360 0.571 rs72728182 chr4:152487027 T/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs4919669 0.668 rs10786700 chr10:104387735 C/T cg05855489 chr10:104503620 C10orf26 0.73 4.67 0.39 7.6e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs9914988 0.943 rs11656256 chr17:27153553 G/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT trans rs66573146 0.831 rs6851488 chr4:6987412 C/T cg07817883 chr1:32538562 TMEM39B 1.33 7.25 0.55 4.02e-11 Granulocyte percentage of myeloid white cells; TGCT trans rs11764590 0.585 rs11772463 chr7:2078132 A/C cg25206134 chr2:45395956 NA 0.97 6.73 0.52 5.68e-10 Neuroticism; TGCT cis rs7267979 1.000 rs6037105 chr20:25374199 C/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10751667 0.666 rs10902247 chr11:953686 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs6545883 0.929 rs12713436 chr2:61691260 T/C cg15711740 chr2:61764176 XPO1 -0.6 -5.5 -0.44 2.09e-7 Tuberculosis; TGCT cis rs6545883 0.929 rs12612982 chr2:61747355 G/A cg15711740 chr2:61764176 XPO1 -0.57 -5.29 -0.43 5.32e-7 Tuberculosis; TGCT cis rs75686122 0.892 rs17806378 chr8:104544502 T/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7833790 0.777 rs1005850 chr8:82692255 G/A cg06027949 chr8:82754900 SNX16 -0.67 -4.47 -0.37 1.75e-5 Diastolic blood pressure; TGCT cis rs10465746 0.967 rs6576956 chr1:84343885 T/G cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs5750830 0.594 rs1010169 chr22:39778167 C/T cg05872129 chr22:39784769 NA 0.87 9.27 0.64 7.32e-16 Intelligence (multi-trait analysis); TGCT cis rs514406 0.861 rs11206026 chr1:53281708 G/A cg25767906 chr1:53392781 SCP2 -0.47 -5.31 -0.43 4.84e-7 Monocyte count; TGCT cis rs231513 0.954 rs231479 chr17:41983616 A/G cg26893861 chr17:41843967 DUSP3 -0.76 -5.44 -0.44 2.67e-7 Cognitive function; TGCT cis rs1801251 0.727 rs6437071 chr2:233568793 G/A cg08000102 chr2:233561755 GIGYF2 0.62 7.0 0.53 1.43e-10 Coronary artery disease; TGCT cis rs2439831 1.000 rs550239 chr15:43720197 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg19318889 chr4:1322082 MAEA 0.27 6.62 0.51 9.72e-10 Longevity; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg18722847 chr3:44754129 ZNF502 -0.4 -4.49 -0.37 1.59e-5 Depressive symptoms; TGCT cis rs11249608 0.548 rs34054398 chr5:178458371 A/G cg21905437 chr5:178450457 ZNF879 0.44 4.62 0.38 9.35e-6 Pubertal anthropometrics; TGCT cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg03188948 chr7:1209495 NA 0.64 5.38 0.43 3.61e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8070740 0.898 rs4442872 chr17:5324236 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.77 0.39 5.14e-6 Menopause (age at onset); TGCT cis rs9467711 0.720 rs1417998 chr6:26162019 T/A cg16898833 chr6:26189333 HIST1H4D 1.02 5.17 0.42 9.02e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs75686122 0.892 rs12681640 chr8:104669409 C/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs208520 0.874 rs208456 chr6:66907942 A/G cg07460842 chr6:66804631 NA -0.9 -9.14 -0.63 1.54e-15 Exhaled nitric oxide output; TGCT cis rs73198271 0.960 rs10503392 chr8:8609555 G/C ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.62 -0.38 9.34e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs13256369 1.000 rs12547721 chr8:8570671 C/T cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs1371867 0.846 rs2439460 chr8:101312665 C/T cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs17125944 0.505 rs2295826 chr14:53174923 C/T cg00686598 chr14:53173677 PSMC6 -1.18 -7.11 -0.54 8.02e-11 Alzheimer's disease (late onset); TGCT cis rs10089 1.000 rs62373701 chr5:127416294 C/T cg19767477 chr5:127420684 SLC12A2 -0.46 -4.84 -0.4 3.74e-6 Ileal carcinoids; TGCT cis rs1153858 1.000 rs4774578 chr15:45646051 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs9430161 0.611 rs34032547 chr1:11034374 C/G cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs6728642 1.000 rs6728642 chr2:97607071 A/G cg26665480 chr2:98280029 ACTR1B -0.92 -5.54 -0.45 1.74e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs6121246 0.909 rs6060679 chr20:30270772 C/G cg13852791 chr20:30311386 BCL2L1 -0.78 -5.8 -0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg03264133 chr6:25882463 NA 0.52 5.51 0.44 2.01e-7 Blood metabolite levels; TGCT cis rs8014252 0.803 rs74062726 chr14:70986179 A/G cg11204974 chr14:71022665 NA -0.53 -4.46 -0.37 1.79e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs112217694 1.000 rs78594675 chr4:104642796 C/A cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs9322193 0.923 rs56397000 chr6:150060483 C/T cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT trans rs564343 0.563 rs574335 chr11:65833266 C/T cg26701943 chr11:108369231 KDELC2 0.72 6.73 0.52 5.71e-10 Obesity (early onset extreme); TGCT cis rs3087591 0.960 rs1124918 chr17:29492423 A/G cg24425628 chr17:29625626 OMG;NF1 -0.46 -7.55 -0.56 8.04e-12 Hip circumference; TGCT cis rs4767364 1.000 rs7977534 chr12:112717920 T/C cg10833066 chr12:111807467 FAM109A 0.33 5.1 0.42 1.23e-6 Oral cavity and pharyngeal cancer; TGCT cis rs225245 0.755 rs7217565 chr17:34024707 C/A cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs9394841 0.692 rs13193235 chr6:41792659 T/C cg08135965 chr6:41755394 TOMM6 0.55 5.17 0.42 9.29e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs877282 0.898 rs11253346 chr10:765313 A/G cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg04013166 chr16:89971882 TCF25 0.32 4.76 0.39 5.31e-6 Skin colour saturation; TGCT cis rs10751667 0.666 rs7395182 chr11:927553 A/C cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs10504229 0.871 rs10504226 chr8:58159283 A/G cg21724239 chr8:58056113 NA 0.39 5.14 0.42 1.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.875 rs11155452 chr6:146424631 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9359856 0.510 rs3736984 chr6:90408589 C/T cg13799429 chr6:90582589 CASP8AP2 0.45 4.66 0.39 7.9e-6 Bipolar disorder; TGCT cis rs1552244 0.688 rs113940455 chr3:10014165 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.85 5.55 0.45 1.66e-7 Alzheimer's disease; TGCT cis rs7635838 0.819 rs4684782 chr3:11518755 C/T cg00170343 chr3:11313890 ATG7 -0.69 -6.67 -0.51 7.44e-10 HDL cholesterol; TGCT cis rs473651 0.777 rs550890 chr2:239332555 G/A cg08773314 chr2:239334832 ASB1 0.49 7.08 0.54 9.56e-11 Multiple system atrophy; TGCT cis rs67072384 1.000 rs55957377 chr11:72445476 A/G cg03713592 chr11:72463424 ARAP1 -0.9 -4.63 -0.38 9.26e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs6988636 1.000 rs16898088 chr8:124190501 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs17270561 0.562 rs74293932 chr6:26014811 C/A cg16482183 chr6:26056742 HIST1H1C 0.97 7.36 0.55 2.21e-11 Iron status biomarkers; TGCT cis rs7666738 0.830 rs9995386 chr4:98907826 T/C cg17366294 chr4:99064904 C4orf37 0.67 6.94 0.53 1.91e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.817 rs7924619 chr11:49620632 G/A cg11707556 chr5:10655725 ANKRD33B -0.38 -7.79 -0.57 2.3e-12 Height; TGCT cis rs3806843 0.676 rs1583005 chr5:140031537 G/A cg19875535 chr5:140030758 IK -0.36 -6.26 -0.49 5.68e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs651907 0.557 rs7629753 chr3:101371922 C/T cg11279151 chr3:101281821 RG9MTD1 0.33 6.92 0.53 2.1e-10 Colorectal cancer; TGCT cis rs8077889 0.672 rs15359 chr17:41843979 C/G cg26893861 chr17:41843967 DUSP3 -1.15 -21.87 -0.89 2.21e-44 Triglycerides; TGCT cis rs10782582 0.609 rs112431348 chr1:76275571 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs6901250 0.851 rs339361 chr6:117162515 C/T cg12892004 chr6:117198278 RFX6 0.58 7.17 0.54 6.08e-11 C-reactive protein levels; TGCT cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.6 6.38 0.5 3.26e-9 Height; TGCT cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg10295955 chr4:187884368 NA -0.97 -14.51 -0.79 1.72e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs9534288 0.762 rs9534264 chr13:46541673 T/A cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs6912958 0.712 rs9444526 chr6:88326402 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs208520 0.821 rs9363572 chr6:67012231 C/T cg07460842 chr6:66804631 NA 0.69 5.72 0.46 7.53e-8 Exhaled nitric oxide output; TGCT cis rs910316 1.000 rs3742773 chr14:75579643 A/G cg11812906 chr14:75593930 NEK9 0.75 7.4 0.55 1.77e-11 Height; TGCT cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg02458000 chr6:26745757 NA 0.56 5.47 0.44 2.41e-7 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.591 rs62148360 chr2:101006319 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.77 0.39 5.1e-6 Intelligence (multi-trait analysis); TGCT cis rs2458413 1.000 rs2458414 chr8:105355840 A/G cg04554929 chr8:105342491 NA 0.52 7.14 0.54 6.76e-11 Paget's disease; TGCT cis rs10782582 0.545 rs111927462 chr1:76195422 A/G cg03433033 chr1:76189801 ACADM -0.59 -6.57 -0.51 1.24e-9 Daytime sleep phenotypes; TGCT cis rs975752 0.717 rs7916126 chr10:102007373 T/C cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs1561288 0.553 rs12988548 chr2:25323083 A/T cg15423357 chr2:25149977 NA -0.5 -4.53 -0.38 1.36e-5 Body mass index; TGCT cis rs2288884 1.000 rs72483951 chr19:52573682 G/C cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs28595532 0.920 rs56302493 chr4:119772382 A/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9916302 0.571 rs28799952 chr17:37533056 C/T cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs1580019 0.883 rs6945294 chr7:32472099 G/A cg06627557 chr7:32535165 LSM5;AVL9 0.83 7.82 0.57 1.98e-12 Cognitive ability; TGCT cis rs6750047 0.625 rs59363818 chr2:38261973 A/C cg07380506 chr2:38303506 CYP1B1 -0.58 -5.2 -0.42 8.09e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs9818758 0.607 rs9837625 chr3:49215966 C/T cg07636037 chr3:49044803 WDR6 -1.04 -5.15 -0.42 1.01e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg06212747 chr3:49208901 KLHDC8B 0.66 6.19 0.49 7.94e-9 Menarche (age at onset); TGCT cis rs1215050 0.740 rs1214997 chr4:99041533 A/T cg05340658 chr4:99064831 C4orf37 0.43 5.27 0.43 5.73e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9894429 1.000 rs7503679 chr17:79583843 G/C cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs7772486 0.875 rs1331640 chr6:146427250 G/A cg05347473 chr6:146136440 FBXO30 0.56 5.21 0.42 7.7e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs763014 0.966 rs4984675 chr16:670117 T/C cg27436995 chr16:743998 FBXL16 -0.47 -5.13 -0.42 1.07e-6 Height; TGCT cis rs910316 0.687 rs175059 chr14:75490667 T/C cg08847533 chr14:75593920 NEK9 -0.84 -8.77 -0.62 1.16e-14 Height; TGCT cis rs835154 0.845 rs835156 chr5:14875813 C/A cg14843632 chr5:14870594 ANKH 0.33 4.6 0.38 1.02e-5 Blood metabolite levels; TGCT cis rs16866061 1.000 rs72974263 chr2:225447371 C/T cg12698349 chr2:225449008 CUL3 1.01 9.99 0.67 1.31e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs7824557 0.547 rs4512344 chr8:11078781 A/C cg21775007 chr8:11205619 TDH -0.51 -4.7 -0.39 6.83e-6 Retinal vascular caliber; TGCT cis rs7044106 0.791 rs10985004 chr9:123484937 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.67 0.51 7.39e-10 Hip circumference adjusted for BMI; TGCT cis rs35146811 0.844 rs12705071 chr7:99682026 T/C cg13334819 chr7:99746414 C7orf59 -0.78 -6.52 -0.51 1.61e-9 Coronary artery disease; TGCT cis rs734999 0.588 rs876938 chr1:2523212 G/C cg18854424 chr1:2615690 NA 0.46 5.23 0.43 6.92e-7 Ulcerative colitis; TGCT cis rs1903068 0.719 rs9284955 chr4:56003117 A/G cg16572876 chr4:56024045 NA -0.43 -4.59 -0.38 1.05e-5 Endometriosis; TGCT cis rs11148252 0.538 rs9535880 chr13:52706143 G/A cg00495681 chr13:53174319 NA 0.57 5.87 0.47 3.78e-8 Lewy body disease; TGCT cis rs6087990 0.806 rs6088008 chr20:31382860 A/G cg13636640 chr20:31349939 DNMT3B 1.06 14.04 0.78 2.21e-27 Ulcerative colitis; TGCT cis rs62103177 0.810 rs62103197 chr18:77632923 G/A cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs56309584 0.560 rs7223859 chr17:8080853 C/T cg08322244 chr17:8066669 VAMP2 0.51 4.83 0.4 3.91e-6 Initial pursuit acceleration; TGCT cis rs4478858 0.735 rs12734617 chr1:31823446 G/T cg07478791 chr1:31886160 SERINC2 -0.47 -4.55 -0.38 1.29e-5 Alcohol dependence; TGCT cis rs12220238 0.908 rs4746179 chr10:75940169 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4713118 0.616 rs9348789 chr6:28025486 C/T cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs12762955 0.561 rs2620942 chr10:1048398 C/T cg18964960 chr10:1102726 WDR37 0.67 5.88 0.47 3.53e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs79976124 0.760 rs74295030 chr6:66654441 T/C cg07460842 chr6:66804631 NA 0.58 5.29 0.43 5.33e-7 Type 2 diabetes; TGCT cis rs2710642 0.886 rs10153716 chr2:63007059 A/G cg17519650 chr2:63277830 OTX1 -0.64 -5.9 -0.47 3.29e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs11748023 0.531 rs155947 chr5:139520556 C/T cg01081189 chr5:139537190 NA 0.26 4.62 0.38 9.35e-6 Intelligence (multi-trait analysis); TGCT cis rs9858542 0.953 rs1873625 chr3:49666964 C/A cg03060546 chr3:49711283 APEH -0.64 -5.7 -0.46 8.18e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7647973 0.961 rs4955417 chr3:49298205 T/C cg05785598 chr3:49045655 WDR6 0.39 4.61 0.38 9.91e-6 Menarche (age at onset); TGCT cis rs3806843 0.676 rs753280 chr5:140024042 C/T cg19875535 chr5:140030758 IK 0.35 6.27 0.49 5.41e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2288884 0.943 rs1433089 chr19:52506985 T/C cg15405931 chr19:52693188 PPP2R1A -0.75 -5.19 -0.42 8.38e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs12477438 0.871 rs13396584 chr2:99611768 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.64 4.86 0.4 3.42e-6 Chronic sinus infection; TGCT cis rs12477438 0.520 rs13022329 chr2:99731189 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs17376456 0.877 rs114256265 chr5:93473130 T/A cg21475434 chr5:93447410 FAM172A 0.61 4.73 0.39 5.98e-6 Diabetic retinopathy; TGCT cis rs9837602 0.507 rs793448 chr3:99532949 G/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.71 0.52 6.1e-10 Breast cancer; TGCT cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg24829409 chr8:58192753 C8orf71 -0.57 -5.38 -0.43 3.63e-7 Developmental language disorder (linguistic errors); TGCT cis rs7705042 0.659 rs11743029 chr5:141509282 G/A cg07392085 chr5:141489673 NDFIP1 -0.34 -4.54 -0.38 1.34e-5 Asthma; TGCT cis rs7412746 0.658 rs4970988 chr1:150950062 A/G cg04414720 chr1:150670196 GOLPH3L -0.39 -4.72 -0.39 6.38e-6 Melanoma; TGCT cis rs11031096 0.754 rs4910886 chr11:4143721 G/T cg18678763 chr11:4115507 RRM1 -0.46 -5.78 -0.46 5.76e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs903263 0.870 rs955492 chr1:84657539 A/T cg09664975 chr1:84543551 PRKACB 0.47 4.48 0.37 1.65e-5 Breast cancer (male); TGCT cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.11 13.91 0.78 4.47e-27 Height; TGCT cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg15659132 chr6:26577336 NA 0.87 10.72 0.69 2.19e-19 Intelligence (multi-trait analysis); TGCT cis rs9393777 0.513 rs9348728 chr6:26634436 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.59 -5.33 -0.43 4.44e-7 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.642 rs2709842 chr4:152370637 C/T cg17479576 chr4:152424074 FAM160A1 0.56 6.0 0.47 2.02e-8 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.704 rs2628179 chr17:28071796 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.95 -0.53 1.82e-10 Coffee consumption (cups per day); TGCT cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg05738196 chr6:26577821 NA 0.88 11.13 0.71 2.26e-20 Intelligence (multi-trait analysis); TGCT cis rs2072499 0.966 rs11587860 chr1:156156951 G/C cg24450063 chr1:156163899 SLC25A44 1.15 15.99 0.82 6.37e-32 Testicular germ cell tumor; TGCT cis rs10832963 1.000 rs10832962 chr11:18656271 C/T cg20219074 chr11:18656078 SPTY2D1 0.98 9.9 0.66 2.19e-17 Breast cancer; TGCT cis rs6831352 0.918 rs2851248 chr4:100045974 A/G cg12011299 chr4:100065546 ADH4 0.39 4.76 0.39 5.29e-6 Alcohol dependence; TGCT cis rs7666738 0.570 rs1869351 chr4:99077286 T/C cg17366294 chr4:99064904 C4orf37 0.58 5.46 0.44 2.55e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9796 0.835 rs11856848 chr15:41370961 C/T cg18705301 chr15:41695430 NDUFAF1 -0.47 -6.09 -0.48 1.34e-8 Menopause (age at onset); TGCT cis rs7647973 0.560 rs77473999 chr3:49777660 T/C cg05785598 chr3:49045655 WDR6 -0.43 -5.13 -0.42 1.07e-6 Menarche (age at onset); TGCT cis rs3849570 0.925 rs6799080 chr3:81905591 G/A cg07356753 chr3:81810745 GBE1 -0.74 -6.77 -0.52 4.57e-10 Waist circumference;Body mass index; TGCT cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.649 rs5758466 chr22:42176059 G/A cg03806693 chr22:41940476 POLR3H 0.9 8.76 0.62 1.2e-14 Vitiligo; TGCT cis rs12048904 0.505 rs6577209 chr1:101255080 A/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.8 6.85 0.52 2.99e-10 Multiple sclerosis; TGCT cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs9291683 0.609 rs7678012 chr4:9993772 T/C cg00071950 chr4:10020882 SLC2A9 0.71 9.25 0.64 8.04e-16 Bone mineral density; TGCT cis rs7017914 0.967 rs13264669 chr8:71626772 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs523522 0.962 rs4766966 chr12:120942911 G/C cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs9913156 0.707 rs72835625 chr17:4560274 G/A cg00122941 chr17:4613640 ARRB2 0.87 7.38 0.55 1.95e-11 Lymphocyte counts; TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg22166914 chr1:53195759 ZYG11B 0.35 5.78 0.46 5.7e-8 Monocyte count; TGCT cis rs12367572 0.965 rs7979717 chr12:45242272 A/T cg04608330 chr12:45269318 NELL2 -0.65 -6.96 -0.53 1.74e-10 Gut microbiome composition (summer); TGCT cis rs116095464 0.558 rs6881920 chr5:222411 T/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs929354 0.772 rs1182448 chr7:157021415 G/A cg05182265 chr7:156933206 UBE3C 0.4 9.05 0.63 2.54e-15 Body mass index; TGCT cis rs2204008 0.837 rs11172728 chr12:38070042 C/A cg26384229 chr12:38710491 ALG10B 0.85 7.76 0.57 2.71e-12 Bladder cancer; TGCT cis rs734999 0.505 rs10797437 chr1:2539006 T/C cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs9303401 0.659 rs7210700 chr17:56668186 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs9467711 0.606 rs34781270 chr6:26593037 A/G cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs57994353 0.568 rs3812581 chr9:139311471 C/T cg13741927 chr9:139327495 INPP5E -0.24 -5.42 -0.44 2.99e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs10276381 0.685 rs56398224 chr7:28205748 A/AT cg23620719 chr7:28220237 JAZF1 0.95 5.05 0.41 1.54e-6 Crohn's disease; TGCT cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg02018176 chr4:1364513 KIAA1530 0.29 4.81 0.4 4.34e-6 Longevity; TGCT cis rs7666738 0.830 rs1534318 chr4:98965058 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.0 0.41 1.9e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.56 -5.32 -0.43 4.76e-7 Prudent dietary pattern; TGCT cis rs3820928 1.000 rs3820927 chr2:227779191 C/A cg11843606 chr2:227700838 RHBDD1 -0.54 -4.92 -0.4 2.75e-6 Pulmonary function; TGCT cis rs13064411 0.696 rs13325046 chr3:113104444 C/T cg10517650 chr3:113235015 CCDC52 -0.35 -4.65 -0.38 8.54e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs514406 0.505 rs856721 chr1:53162156 C/A cg25767906 chr1:53392781 SCP2 -0.45 -4.85 -0.4 3.64e-6 Monocyte count; TGCT cis rs1580019 0.961 rs4255041 chr7:32496383 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg00024416 chr22:24240387 NA -0.25 -4.79 -0.39 4.74e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9810089 0.814 rs864437 chr3:136119909 C/G cg12473912 chr3:136751656 NA 0.36 5.04 0.41 1.58e-6 Gestational age at birth (child effect); TGCT cis rs9818758 0.607 rs113186424 chr3:49272726 T/C cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs10986311 0.832 rs10119911 chr9:127127172 A/G cg14243010 chr9:127117328 LOC100129034;PSMB7 0.21 4.97 0.41 2.13e-6 Vitiligo; TGCT cis rs587847 0.737 rs4924154 chr15:37666384 C/T cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs7666738 0.791 rs13146909 chr4:98934198 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs16924631 0.518 rs7033570 chr9:6440123 G/A cg13560576 chr9:5833327 ERMP1 0.78 4.63 0.38 9.23e-6 Periodontal microbiota; TGCT cis rs10984561 0.881 rs7032085 chr9:122253740 G/T cg14242995 chr9:122249943 NA 0.74 6.01 0.47 1.96e-8 Pulmonary function decline; TGCT cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.62e-9 Blood metabolite levels; TGCT cis rs7772486 0.754 rs9386132 chr6:146140751 T/C cg13319975 chr6:146136371 FBXO30 -0.57 -5.1 -0.42 1.22e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9527 0.590 rs1926029 chr10:104855670 C/T cg04362960 chr10:104952993 NT5C2 0.65 5.38 0.43 3.64e-7 Arsenic metabolism; TGCT cis rs11096990 0.593 rs7662880 chr4:39285224 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.46e-5 Cognitive function; TGCT cis rs7666738 0.830 rs3857217 chr4:99034347 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4455778 0.664 rs12718313 chr7:49024855 G/A cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs2361718 0.500 rs4889818 chr17:78085228 A/G cg22255288 chr17:78854418 RPTOR -0.25 -4.55 -0.38 1.27e-5 Yeast infection; TGCT cis rs801193 1.000 rs2707845 chr7:66198798 C/T cg00343986 chr7:65444356 GUSB 0.24 5.25 0.43 6.3e-7 Aortic root size; TGCT cis rs6089829 0.888 rs4809467 chr20:61671688 A/G cg03213289 chr20:61660250 NA 0.72 9.45 0.65 2.69e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7647973 0.593 rs9870755 chr3:49809841 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.8 0.4 4.49e-6 Menarche (age at onset); TGCT cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4862750 0.872 rs7664463 chr4:187876686 A/C cg10295955 chr4:187884368 NA -0.96 -14.31 -0.79 5.02e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg25703541 chr22:24373054 LOC391322 -0.81 -8.7 -0.62 1.68e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg16145915 chr7:1198662 ZFAND2A -0.61 -8.65 -0.61 2.24e-14 Longevity;Endometriosis; TGCT cis rs7666738 0.830 rs6831925 chr4:98947401 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8077577 0.945 rs8069094 chr17:18096528 C/T cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT trans rs1005277 0.579 rs2472182 chr10:38388865 T/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs7772486 0.806 rs2265477 chr6:146212338 T/C cg23711669 chr6:146136114 FBXO30 0.83 9.16 0.64 1.32e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs13256369 0.826 rs12678414 chr8:8586016 G/T cg17143192 chr8:8559678 CLDN23 0.58 5.25 0.43 6.26e-7 Obesity-related traits; TGCT trans rs7824557 0.564 rs2572392 chr8:11235605 T/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.48e-10 Retinal vascular caliber; TGCT cis rs12541335 0.603 rs9792127 chr8:22180334 G/A cg18135555 chr8:22132992 PIWIL2 0.3 6.14 0.48 1.02e-8 Hypertriglyceridemia; TGCT cis rs7568458 0.846 rs6705971 chr2:85761417 G/T cg17127132 chr2:85788382 GGCX -0.55 -5.38 -0.43 3.63e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs12681287 0.547 rs9297921 chr8:87542286 C/T cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT cis rs2932538 0.922 rs61818800 chr1:113148571 A/G cg22162597 chr1:113214053 CAPZA1 0.23 4.71 0.39 6.44e-6 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT trans rs797680 0.822 rs1572343 chr1:93616202 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.77 -0.52 4.54e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9911578 0.817 rs304264 chr17:56749628 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.29 -0.49 5.01e-9 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.520 rs59916147 chr21:40634702 T/G cg11644478 chr21:40555479 PSMG1 -0.52 -4.79 -0.4 4.64e-6 Menarche (age at onset); TGCT cis rs11190604 1.000 rs2273694 chr10:102256496 G/T cg23241863 chr10:102295624 HIF1AN 0.69 5.31 0.43 4.99e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7647973 1.000 rs3448 chr3:49396751 T/C cg06212747 chr3:49208901 KLHDC8B 0.59 4.7 0.39 6.94e-6 Menarche (age at onset); TGCT cis rs4455778 0.539 rs7780870 chr7:49014630 A/G cg26309511 chr7:48887640 NA -0.44 -5.68 -0.45 9.03e-8 Lung cancer in never smokers; TGCT cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs8078723 0.901 rs709591 chr17:38175561 T/A cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg25767906 chr1:53392781 SCP2 -0.57 -6.81 -0.52 3.8e-10 Monocyte count; TGCT cis rs1865760 0.663 rs9348704 chr6:26000393 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.7 6.81 0.52 3.72e-10 Height; TGCT cis rs7666738 0.830 rs28867087 chr4:98880349 T/A cg05340658 chr4:99064831 C4orf37 0.54 6.13 0.48 1.06e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13242816 1.000 rs3807995 chr7:116197976 C/T cg16553024 chr7:116138462 CAV2 -0.44 -5.23 -0.43 7e-7 P wave duration; TGCT cis rs6964587 1.000 rs2299238 chr7:91654517 G/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs7937682 0.883 rs659529 chr11:111436896 T/A cg09085632 chr11:111637200 PPP2R1B -0.98 -10.12 -0.67 6.37e-18 Primary sclerosing cholangitis; TGCT cis rs9914544 1.000 rs1634409 chr17:18836177 C/T cg26378065 chr17:18585709 ZNF286B 0.54 4.85 0.4 3.67e-6 Educational attainment (years of education); TGCT cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg26531700 chr6:26746687 NA 0.51 4.77 0.39 5.07e-6 Intelligence (multi-trait analysis); TGCT cis rs9486715 1.000 rs6899647 chr6:97065661 A/G cg06623918 chr6:96969491 KIAA0776 -1.08 -13.52 -0.77 3.67e-26 Headache; TGCT cis rs597539 0.652 rs602364 chr11:68662167 C/T cg21862992 chr11:68658383 NA 0.47 6.58 0.51 1.19e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6866344 0.697 rs62392823 chr5:178126968 T/C cg03877680 chr5:178157825 ZNF354A 0.73 5.72 0.46 7.46e-8 Neutrophil percentage of white cells; TGCT cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg19729930 chr2:74357872 NA 0.57 7.78 0.57 2.42e-12 Gestational age at birth (maternal effect); TGCT cis rs6671200 0.607 rs3753872 chr1:95699184 T/G cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs34014631 1.000 rs3758557 chr10:103572925 A/G cg22630918 chr10:102748988 C10orf2 0.43 4.8 0.4 4.57e-6 Coronary artery calcification; TGCT cis rs9894429 1.000 rs9748176 chr17:79584043 C/G cg18240062 chr17:79603768 NPLOC4 0.7 7.23 0.54 4.45e-11 Eye color traits; TGCT cis rs1062177 0.901 rs1549622 chr5:151266049 A/G cg12924095 chr5:151150029 G3BP1 0.35 4.81 0.4 4.36e-6 Preschool internalizing problems; TGCT cis rs6121246 0.559 rs6060932 chr20:30350545 A/G cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs35306767 0.903 rs12244355 chr10:944465 T/C cg26597838 chr10:835615 NA 0.76 10.69 0.69 2.61e-19 Eosinophil percentage of granulocytes; TGCT cis rs6598955 0.671 rs17257169 chr1:26570009 C/T cg04990556 chr1:26633338 UBXN11 0.61 5.26 0.43 6.13e-7 Obesity-related traits; TGCT cis rs2486288 0.656 rs12899058 chr15:45547324 G/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg06873352 chr17:61820015 STRADA 0.55 5.69 0.46 8.57e-8 Prudent dietary pattern; TGCT cis rs3749237 0.964 rs34522271 chr3:49808517 A/G cg03060546 chr3:49711283 APEH 0.72 7.36 0.55 2.17e-11 Resting heart rate; TGCT cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg16558208 chr1:156270281 VHLL -0.27 -4.83 -0.4 3.87e-6 Tonsillectomy; TGCT cis rs9633740 0.945 rs6586030 chr10:82254047 C/T cg01528321 chr10:82214614 TSPAN14 -0.9 -7.09 -0.54 9.14e-11 Post bronchodilator FEV1; TGCT cis rs4819052 1.000 rs4819052 chr21:46699777 A/G cg06618935 chr21:46677482 NA -0.38 -4.98 -0.41 2.08e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs2204008 0.594 rs2711545 chr12:38061039 C/T cg26384229 chr12:38710491 ALG10B 0.58 4.96 0.41 2.24e-6 Bladder cancer; TGCT cis rs7312933 0.669 rs7974476 chr12:42542484 C/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.57 5.24 0.43 6.8e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2439831 0.681 rs28578454 chr15:43603032 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.94 6.23 0.49 6.7e-9 Lung cancer in ever smokers; TGCT cis rs9611519 0.761 rs35445172 chr22:41660301 G/A cg13695892 chr22:41940480 POLR3H -0.64 -6.05 -0.48 1.58e-8 Neuroticism; TGCT cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg11890956 chr21:40555474 PSMG1 -0.76 -7.39 -0.55 1.87e-11 Cognitive function; TGCT cis rs2836974 0.830 rs2735309 chr21:40715313 C/T cg11890956 chr21:40555474 PSMG1 0.99 9.11 0.63 1.78e-15 Cognitive function; TGCT cis rs13064411 0.696 rs9839921 chr3:113199093 G/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs2439831 0.618 rs8023508 chr15:44176103 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.66 -4.64 -0.38 8.61e-6 Lung cancer in ever smokers; TGCT cis rs13191362 1.000 rs36107456 chr6:162997399 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7843479 0.601 rs2002941 chr8:21834366 A/C cg17168535 chr8:21777572 XPO7 0.8 8.11 0.59 4.09e-13 Mean corpuscular volume; TGCT cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg17554472 chr22:41940697 POLR3H 0.48 5.14 0.42 1.05e-6 Vitiligo; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg01577475 chr2:114033581 PAX8;LOC440839 -0.44 -4.75 -0.39 5.42e-6 Lymphocyte counts; TGCT trans rs17685 0.753 rs6465000 chr7:75787417 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg04025307 chr7:1156635 C7orf50 0.24 5.59 0.45 1.39e-7 Longevity;Endometriosis; TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg17178900 chr1:205818956 PM20D1 0.66 9.32 0.64 5.66e-16 Menarche (age at onset); TGCT cis rs1801251 1.000 rs283484 chr2:233646505 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.52 0.51 1.58e-9 Coronary artery disease; TGCT cis rs75686122 0.655 rs4472479 chr8:104624760 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.82e-10 Electroencephalogram traits; TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg03407747 chr17:6899364 ALOX12 -0.48 -5.37 -0.43 3.8e-7 Tonsillectomy; TGCT cis rs17384381 1.000 rs79695640 chr1:85836073 T/C cg16011679 chr1:85725395 C1orf52 0.84 6.52 0.51 1.6e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs734999 0.572 rs2985857 chr1:2532624 C/T cg18854424 chr1:2615690 NA -0.44 -5.1 -0.42 1.22e-6 Ulcerative colitis; TGCT cis rs6882046 0.513 rs1081158 chr5:88004616 C/T cg22951263 chr5:87985283 NA -0.59 -6.28 -0.49 5.21e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs514406 0.505 rs387436 chr1:53179376 C/T cg25767906 chr1:53392781 SCP2 0.47 5.35 0.43 4.15e-7 Monocyte count; TGCT cis rs11203032 0.831 rs7477966 chr10:90924258 A/G cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs12971120 0.891 rs12968731 chr18:72169708 G/T cg26446133 chr18:72167187 CNDP2 -0.37 -6.33 -0.49 4.13e-9 Refractive error; TGCT cis rs9818758 0.556 rs9814987 chr3:49207849 T/C cg07636037 chr3:49044803 WDR6 -1.02 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6835098 0.692 rs10520252 chr4:174070959 T/C cg08422745 chr4:174089978 GALNT7 -0.77 -8.6 -0.61 2.87e-14 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs9419702 0.538 rs9322837 chr10:133539229 G/A cg23460707 chr10:133558971 NA 0.43 4.85 0.4 3.57e-6 Survival in rectal cancer; TGCT cis rs12579753 0.913 rs12579018 chr12:82231943 T/C cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs928736 0.557 rs2834083 chr21:34436973 A/G cg00274965 chr21:34405681 NA 0.52 5.93 0.47 2.81e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs10464366 0.746 rs4723821 chr7:39141532 A/G cg15212455 chr7:39170539 POU6F2 0.26 5.62 0.45 1.19e-7 IgG glycosylation; TGCT cis rs7937682 0.737 rs542275 chr11:111431614 C/T cg09085632 chr11:111637200 PPP2R1B -0.79 -8.12 -0.59 4e-13 Primary sclerosing cholangitis; TGCT cis rs6840360 0.571 rs72730104 chr4:152543857 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs929354 0.772 rs1182360 chr7:157020550 C/G cg05182265 chr7:156933206 UBE3C -0.4 -9.08 -0.63 2.11e-15 Body mass index; TGCT cis rs8017423 0.935 rs7144335 chr14:90732280 A/G cg04374321 chr14:90722782 PSMC1 -0.79 -7.85 -0.58 1.66e-12 Mortality in heart failure; TGCT cis rs12971120 1.000 rs3829640 chr18:72174980 A/G cg26446133 chr18:72167187 CNDP2 -0.34 -6.31 -0.49 4.51e-9 Refractive error; TGCT cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg16049864 chr8:95962084 TP53INP1 -0.76 -11.14 -0.71 2.13e-20 Type 2 diabetes; TGCT cis rs9811920 0.638 rs796977 chr3:99549723 T/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 6.82 0.52 3.63e-10 Axial length; TGCT cis rs1218582 0.710 rs4845685 chr1:154878300 C/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs7208859 0.673 rs60020217 chr17:29185054 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7017914 0.967 rs6999739 chr8:71637212 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs929354 0.772 rs2301914 chr7:157000176 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.77 -0.62 1.19e-14 Body mass index; TGCT cis rs7552404 1.000 rs1498315 chr1:76159225 G/A cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2070488 0.730 rs2268759 chr3:38514327 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.8 8.08 0.59 4.79e-13 Electrocardiographic conduction measures; TGCT cis rs13202913 0.709 rs11965449 chr6:151830598 C/T cg03627880 chr6:151815985 C6orf97 0.56 5.88 0.47 3.48e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs35146811 0.700 rs2950520 chr7:99827148 T/C cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -5.09 -0.42 1.31e-6 Coronary artery disease; TGCT cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs3008870 1.000 rs58680688 chr1:67443751 C/G cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs2718812 0.766 rs12497513 chr3:133388670 C/G cg16414030 chr3:133502952 NA 0.4 5.32 0.43 4.76e-7 Iron status biomarkers; TGCT cis rs9486715 1.000 rs2273621 chr6:97058553 A/G cg18709589 chr6:96969512 KIAA0776 -0.78 -7.29 -0.55 3.22e-11 Headache; TGCT cis rs921968 0.541 rs41461846 chr2:219313354 A/G cg02176678 chr2:219576539 TTLL4 -0.51 -7.35 -0.55 2.31e-11 Mean corpuscular hemoglobin concentration; TGCT cis rs1670533 1.000 rs4690213 chr4:1054868 C/T cg27284194 chr4:1044797 NA 0.68 5.88 0.47 3.56e-8 Recombination rate (females); TGCT cis rs3809566 0.632 rs9806533 chr15:63328298 A/G cg08198488 chr15:63333792 TPM1 -0.33 -4.97 -0.41 2.15e-6 Platelet count; TGCT cis rs6460942 1.000 rs6460938 chr7:12406808 T/G cg06484146 chr7:12443880 VWDE -0.57 -5.34 -0.43 4.36e-7 Coronary artery disease; TGCT cis rs981844 0.712 rs1037652 chr4:154746565 C/T cg14289246 chr4:154710475 SFRP2 0.99 9.12 0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs7552404 0.960 rs12085123 chr1:76149749 G/A cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17253792 0.822 rs74609892 chr14:56053002 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg18765753 chr7:1198926 ZFAND2A -0.53 -6.22 -0.49 7.09e-9 Longevity;Endometriosis; TGCT cis rs2933343 0.729 rs789231 chr3:128602847 A/G cg11901034 chr3:128598214 ACAD9 -0.68 -6.63 -0.51 9.16e-10 IgG glycosylation; TGCT cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg23649088 chr2:200775458 C2orf69 0.47 9.78 0.66 4.27e-17 Osteoporosis; TGCT cis rs11785400 0.793 rs750530 chr8:143744931 G/A cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs597539 0.652 rs1249474 chr11:68654774 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.05 0.59 5.82e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg21672276 chr3:44754072 ZNF502 -0.41 -4.62 -0.38 9.62e-6 Depressive symptoms; TGCT cis rs80282103 0.618 rs74117850 chr10:1165777 T/C cg08668510 chr10:1095578 IDI1 1.07 5.04 0.41 1.59e-6 Glomerular filtration rate (creatinine); TGCT cis rs9372498 0.572 rs62422230 chr6:118959436 T/C cg21191810 chr6:118973309 C6orf204 -0.38 -4.98 -0.41 2.04e-6 Diastolic blood pressure; TGCT cis rs739496 0.615 rs4646777 chr12:112230036 G/A cg10833066 chr12:111807467 FAM109A 0.36 4.67 0.39 7.74e-6 Platelet count; TGCT cis rs8070128 0.534 rs2955350 chr17:17953548 G/A cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT trans rs4332037 0.539 rs55988458 chr7:2059761 G/A cg10840412 chr1:235813424 GNG4 0.94 6.84 0.52 3.21e-10 Bipolar disorder; TGCT cis rs9467773 0.587 rs9467722 chr6:26352566 T/C cg05738196 chr6:26577821 NA -0.62 -6.72 -0.52 5.8e-10 Intelligence (multi-trait analysis); TGCT cis rs9388451 0.772 rs1268064 chr6:126042578 G/A cg05901451 chr6:126070800 HEY2 0.98 12.62 0.75 5.47e-24 Brugada syndrome; TGCT cis rs9291683 0.609 rs55959894 chr4:10026580 G/A cg11266682 chr4:10021025 SLC2A9 0.66 9.53 0.65 1.78e-16 Bone mineral density; TGCT cis rs12995491 0.569 rs6724281 chr2:88529531 T/G cg04511125 chr2:88470314 THNSL2 -0.47 -4.44 -0.37 1.96e-5 Response to metformin (IC50); TGCT cis rs631288 0.557 rs4534444 chr1:146679283 T/C cg25205988 chr1:146714368 CHD1L 1.33 5.42 0.44 2.97e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs752092 1.000 rs7182945 chr15:101784223 C/T cg25114630 chr15:101792522 CHSY1 0.57 5.54 0.45 1.71e-7 Corneal structure; TGCT trans rs1908814 0.516 rs4840597 chr8:11796068 A/C cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs11208691 0.520 rs4655795 chr1:66159368 G/T cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 Lymphocyte percentage of white cells; TGCT cis rs1868673 0.545 rs10804747 chr3:150094926 A/C cg24290546 chr3:150134309 TSC22D2 -0.3 -4.75 -0.39 5.42e-6 Waist circumference; TGCT cis rs17030434 0.953 rs6535953 chr4:154728186 G/A cg14289246 chr4:154710475 SFRP2 -0.89 -7.01 -0.53 1.33e-10 Electrocardiographic conduction measures; TGCT cis rs12711979 0.509 rs1031478 chr2:3827425 G/A cg17052675 chr2:3827356 NA -0.56 -13.37 -0.77 8.42e-26 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs1552244 1.000 rs17032414 chr3:10158302 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.94 -0.53 1.89e-10 Alzheimer's disease; TGCT cis rs75059851 0.756 rs7122746 chr11:133838808 A/G cg14047540 chr11:133829660 NA -0.5 -5.04 -0.41 1.61e-6 Schizophrenia; TGCT cis rs1218582 0.772 rs4845688 chr1:154884142 T/C cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs739496 0.947 rs55851737 chr12:111936838 T/C cg10833066 chr12:111807467 FAM109A 0.37 5.16 0.42 9.31e-7 Platelet count; TGCT cis rs7659604 0.521 rs10001697 chr4:122677737 G/T cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs12497850 1.000 rs1352420 chr3:48757291 A/G cg06212747 chr3:49208901 KLHDC8B 0.62 5.72 0.46 7.46e-8 Parkinson's disease; TGCT cis rs9581857 0.547 rs9581877 chr13:28104321 T/A cg22138327 chr13:27999177 GTF3A 0.72 4.75 0.39 5.45e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs11098499 0.863 rs12502389 chr4:120454191 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs1372520 0.684 rs356191 chr4:90688120 G/A cg20003494 chr4:90757398 SNCA 0.56 4.46 0.37 1.83e-5 Neuroticism; TGCT cis rs2562456 0.958 rs2562508 chr19:21726281 G/A cg01304269 chr19:21688519 ZNF429 -0.57 -4.77 -0.39 5.02e-6 Pain; TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs72781680 0.716 rs2551326 chr2:23982378 T/C cg08917208 chr2:24149416 ATAD2B 0.75 5.04 0.41 1.59e-6 Lymphocyte counts; TGCT cis rs9733 0.596 rs72700897 chr1:150626038 C/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs10791097 0.690 rs12284487 chr11:130729705 T/C cg12179176 chr11:130786555 SNX19 0.73 8.69 0.62 1.75e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7772486 0.597 rs1970306 chr6:146154543 A/G cg13319975 chr6:146136371 FBXO30 -0.67 -6.06 -0.48 1.53e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 0.967 rs12148805 chr15:76800659 G/A cg26408565 chr15:76604113 ETFA -0.41 -5.28 -0.43 5.48e-7 Blood metabolite levels; TGCT cis rs12145833 0.596 rs12043646 chr1:243281992 G/A cg02356786 chr1:243265016 LOC731275 0.52 4.53 0.38 1.36e-5 Obesity (early onset extreme); TGCT cis rs6088580 0.634 rs2378134 chr20:32938085 C/T cg06115741 chr20:33292138 TP53INP2 -0.56 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs9341808 0.718 rs910266 chr6:80921170 A/T cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs12497850 0.931 rs6446196 chr3:49004723 A/G cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.94e-6 Parkinson's disease; TGCT cis rs950169 0.526 rs698620 chr15:85177208 G/A cg17173187 chr15:85201210 NMB -0.47 -5.88 -0.47 3.59e-8 Schizophrenia; TGCT cis rs9611565 0.607 rs132792 chr22:42062822 C/T cg13695892 chr22:41940480 POLR3H 0.83 8.01 0.58 7.22e-13 Vitiligo; TGCT cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8077889 0.917 rs4793037 chr17:41914826 C/T cg26893861 chr17:41843967 DUSP3 1.11 13.36 0.77 8.83e-26 Triglycerides; TGCT cis rs807669 0.934 rs762523 chr22:19180589 A/G cg02655711 chr22:19163373 SLC25A1 0.42 9.94 0.67 1.76e-17 Metabolite levels; TGCT cis rs10501293 0.912 rs4755694 chr11:43088582 A/G cg03447554 chr11:43094025 NA -0.47 -6.61 -0.51 1.04e-9 Cognitive performance; TGCT cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg15687855 chr3:44754131 ZNF502 -0.52 -6.31 -0.49 4.59e-9 Depressive symptoms; TGCT cis rs9302065 0.565 rs2993584 chr13:95961678 C/A cg26751094 chr13:95954534 ABCC4 -0.4 -6.74 -0.52 5.33e-10 Blood metabolite levels; TGCT cis rs28735056 0.904 rs72980087 chr18:77632194 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs10949662 0.961 rs75323120 chr7:157529590 C/A cg14168080 chr7:157504135 PTPRN2 -0.39 -4.6 -0.38 1.05e-5 Intelligence (multi-trait analysis); TGCT trans rs77457752 0.525 rs1923351 chr9:13898902 G/A cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.21e-10 Breast cancer; TGCT cis rs9486719 1.000 rs3798296 chr6:97052286 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs75229567 0.717 rs77874289 chr12:70234203 A/G cg10114359 chr12:70132523 RAB3IP 1.55 7.66 0.57 4.5e-12 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs17767294 0.708 rs72848767 chr6:27909287 C/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs9902453 0.836 rs62070337 chr17:28466257 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs10193935 1.000 rs10193935 chr2:42419829 C/T cg27598129 chr2:42591480 NA -0.4 -5.44 -0.44 2.73e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7714584 1.000 rs11739677 chr5:150294883 A/G cg22134413 chr5:150180641 NA 1.01 7.24 0.55 4.17e-11 Crohn's disease; TGCT cis rs12477438 0.765 rs2309454 chr2:99595418 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs79057730 0.639 rs6463933 chr7:793954 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.69 6.59 0.51 1.11e-9 Initial pursuit acceleration; TGCT cis rs7582180 0.629 rs2164847 chr2:100958715 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs12510870 0.599 rs28838047 chr4:74410925 C/T cg05868023 chr4:75230803 EREG 0.56 5.14 0.42 1.06e-6 Iris color (b* coordinate); TGCT cis rs42648 0.869 rs1015403 chr7:89913702 A/G cg25739043 chr7:89950458 NA -0.73 -7.31 -0.55 2.87e-11 Homocysteine levels; TGCT cis rs7975161 0.624 rs11111943 chr12:104632418 T/C cg25273343 chr12:104657179 TXNRD1 -0.35 -4.83 -0.4 3.87e-6 Toenail selenium levels; TGCT cis rs7959452 0.535 rs4761228 chr12:69682327 G/A cg20891283 chr12:69753455 YEATS4 0.65 6.39 0.5 3.1e-9 Blood protein levels; TGCT trans rs1864729 1.000 rs2567773 chr8:98279182 G/A cg08679828 chr8:102218111 ZNF706 -1.1 -7.71 -0.57 3.56e-12 Estradiol plasma levels (breast cancer); TGCT trans rs34421088 0.560 rs2248325 chr8:11396874 A/G cg15556689 chr8:8085844 FLJ10661 -0.75 -7.08 -0.54 9.46e-11 Neuroticism; TGCT cis rs514406 0.584 rs7548832 chr1:53193576 A/T cg08736216 chr1:53307985 ZYG11A -0.24 -4.48 -0.37 1.68e-5 Monocyte count; TGCT cis rs6714788 0.565 rs12712063 chr2:100663281 C/T cg07810366 chr2:100720526 AFF3 -0.37 -5.53 -0.44 1.82e-7 Intelligence (multi-trait analysis); TGCT cis rs711245 0.637 rs6729495 chr2:36834192 T/A cg10546459 chr2:36825355 FEZ2 0.57 5.39 0.44 3.48e-7 Height; TGCT cis rs6671200 0.607 rs3767315 chr1:95705972 A/G cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT trans rs11082490 1.000 rs61104666 chr18:43420177 G/A cg05654096 chr12:106477691 NUAK1 0.55 6.66 0.51 8.03e-10 Response to paliperidone in schizophrenia (positive Marder score);Response to paliperidone in schizophrenia (PANSS score); TGCT trans rs1974653 0.672 rs9606243 chr22:20080927 A/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs7945705 0.692 rs11042149 chr11:9010737 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -4.82 -0.4 4.11e-6 Hemoglobin concentration; TGCT cis rs12049351 0.774 rs12024146 chr1:229660891 C/T cg12130225 chr1:229698885 NA 0.38 4.63 0.38 8.95e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs9300255 0.602 rs1790095 chr12:123681222 G/A cg00376283 chr12:123451042 ABCB9 0.72 5.61 0.45 1.27e-7 Neutrophil percentage of white cells; TGCT cis rs10836699 0.586 rs2662199 chr11:37200795 A/C cg18520238 chr11:36422557 PRR5L 0.18 4.52 0.38 1.41e-5 Low high density lipoprotein cholesterol levels; TGCT cis rs9611565 0.546 rs5758426 chr22:42098763 T/G cg17554472 chr22:41940697 POLR3H 0.47 5.06 0.41 1.46e-6 Vitiligo; TGCT cis rs301043 0.500 rs2596765 chr12:95896810 G/A cg07805603 chr12:95869602 METAP2 0.41 5.19 0.42 8.35e-7 Immature fraction of reticulocytes; TGCT cis rs12145833 0.538 rs9803701 chr1:243391634 T/C cg02356786 chr1:243265016 LOC731275 -0.59 -5.11 -0.42 1.18e-6 Obesity (early onset extreme); TGCT cis rs28595532 0.925 rs116785973 chr4:119611350 G/A cg14228332 chr4:119757509 SEC24D 1.0 5.76 0.46 6.22e-8 Cannabis dependence symptom count; TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg09737314 chr17:6899359 ALOX12 -0.44 -4.82 -0.4 4.08e-6 Tonsillectomy; TGCT cis rs2658782 0.547 rs3020064 chr11:93060851 A/G cg15737290 chr11:93063684 CCDC67 1.04 11.37 0.71 5.74e-21 Pulmonary function decline; TGCT cis rs13108904 0.901 rs4493484 chr4:1279944 G/A cg03303774 chr4:1407052 NA 0.31 4.96 0.41 2.25e-6 Obesity-related traits; TGCT cis rs9814567 0.762 rs13071852 chr3:134223217 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.83 6.53 0.51 1.51e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4950928 0.823 rs2486065 chr1:203167871 A/G cg17014757 chr1:203156097 CHI3L1 -0.37 -4.76 -0.39 5.19e-6 YKL-40 levels; TGCT cis rs6570726 0.875 rs12524077 chr6:145866333 G/C cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2439831 0.850 rs11070408 chr15:44034788 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs7552404 0.924 rs1146580 chr1:76209935 T/C cg03433033 chr1:76189801 ACADM 0.77 9.25 0.64 8.26e-16 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs877282 0.842 rs7092986 chr10:756373 G/A cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs6589563 0.737 rs73588403 chr11:116628271 C/T cg01124546 chr11:117515332 DSCAML1 -0.45 -4.85 -0.4 3.69e-6 Eosinophil counts; TGCT cis rs1062177 0.951 rs2915876 chr5:151150745 C/A cg00977110 chr5:151150581 G3BP1 0.4 4.57 0.38 1.18e-5 Preschool internalizing problems; TGCT cis rs7086627 0.515 rs7078254 chr10:82212193 C/T cg00277334 chr10:82204260 NA -0.56 -8.71 -0.62 1.61e-14 Post bronchodilator FEV1; TGCT cis rs478304 0.651 rs11227299 chr11:65549570 C/G cg17480646 chr11:65405466 SIPA1 -0.55 -6.43 -0.5 2.55e-9 Acne (severe); TGCT cis rs12497850 1.000 rs4858828 chr3:48724811 C/T cg07636037 chr3:49044803 WDR6 0.92 10.34 0.68 1.91e-18 Parkinson's disease; TGCT cis rs6088590 1.000 rs6087625 chr20:33342477 A/G cg06115741 chr20:33292138 TP53INP2 -0.68 -5.7 -0.46 8.23e-8 Coronary artery disease; TGCT cis rs7267979 1.000 rs2482940 chr20:25349830 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3757318 0.540 rs6916386 chr6:151853773 G/C cg18745416 chr6:152011399 ESR1 0.54 4.89 0.4 3.06e-6 Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative);Breast cancer; TGCT cis rs514406 0.584 rs7548832 chr1:53193576 A/T cg01802117 chr1:53393560 SCP2 -0.4 -4.63 -0.38 9.22e-6 Monocyte count; TGCT cis rs10992471 0.756 rs2761681 chr9:95186937 A/G cg14631576 chr9:95140430 CENPP -0.3 -4.97 -0.41 2.21e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs637571 0.584 rs594689 chr11:65635559 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.63 -6.57 -0.51 1.24e-9 Eosinophil percentage of white cells; TGCT cis rs263156 1.000 rs263157 chr6:142908618 A/G cg18419694 chr6:143832440 FUCA2 0.4 4.65 0.39 8.22e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs1568889 1.000 rs7949057 chr11:28255053 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.82 8.44 0.6 6.97e-14 Bipolar disorder; TGCT cis rs9296092 0.560 rs9469511 chr6:33530930 T/G cg13560919 chr6:33536144 NA -0.22 -4.95 -0.41 2.33e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT trans rs7726839 0.561 rs11955068 chr5:582324 C/T cg11887960 chr12:57824829 NA 0.98 7.81 0.57 2.09e-12 Obesity-related traits; TGCT cis rs2836974 0.545 rs8128901 chr21:40710419 G/A cg17971929 chr21:40555470 PSMG1 0.6 5.52 0.44 1.92e-7 Cognitive function; TGCT cis rs7666738 0.830 rs4292342 chr4:98959870 A/T cg18180107 chr4:99064573 C4orf37 0.58 5.39 0.44 3.4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs9406165 chr6:8488837 C/T cg23788917 chr6:8435910 SLC35B3 0.62 5.64 0.45 1.11e-7 Motion sickness; TGCT cis rs4819052 0.851 rs2838840 chr21:46668494 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 6.95 0.53 1.86e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7769051 1.000 rs12203977 chr6:133122760 A/G cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs6845621 0.716 rs13142105 chr4:18882307 A/T cg12196642 chr4:18937545 NA -0.24 -4.49 -0.37 1.62e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs2456568 0.802 rs10765638 chr11:93636171 A/T cg17595323 chr11:93583763 C11orf90 -0.47 -6.44 -0.5 2.38e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4849845 0.637 rs13022486 chr2:121038611 C/T cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs9381040 0.655 rs7738684 chr6:41038552 G/A cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs769267 0.899 rs3934667 chr19:19431423 T/G cg19010396 chr19:19431384 KIAA0892;SF4 -0.55 -4.6 -0.38 1.02e-5 Tonsillectomy; TGCT cis rs4148883 0.504 rs28720150 chr4:100132790 T/G cg12011299 chr4:100065546 ADH4 -0.36 -5.17 -0.42 9.13e-7 Alcohol dependence; TGCT cis rs9611519 0.929 rs73174657 chr22:41434158 G/A cg13695892 chr22:41940480 POLR3H -0.53 -4.62 -0.38 9.54e-6 Neuroticism; TGCT cis rs1552244 0.554 rs13081079 chr3:10056348 A/G cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs4273100 0.790 rs60166680 chr17:19277544 C/G cg01534423 chr17:18965556 NA 0.9 6.05 0.48 1.62e-8 Schizophrenia; TGCT cis rs546131 0.928 rs546521 chr11:34824773 G/C cg11058730 chr11:34937778 PDHX;APIP 0.54 4.81 0.4 4.36e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7618915 0.501 rs2164885 chr3:52731269 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.93e-10 Bipolar disorder; TGCT cis rs35000415 0.688 rs13237546 chr7:128720433 G/A cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs6095298 0.553 rs112601802 chr20:47453884 T/C cg12307787 chr20:48099359 KCNB1 0.42 4.51 0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs4975709 0.589 rs1466607 chr5:1864856 A/G cg12288994 chr5:1860383 NA 0.25 5.02 0.41 1.78e-6 Cardiovascular disease risk factors; TGCT cis rs2836974 0.932 rs35571600 chr21:40590624 A/C cg11890956 chr21:40555474 PSMG1 1.1 12.31 0.74 2.99e-23 Cognitive function; TGCT cis rs367943 1.000 rs348954 chr5:112821716 A/G cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg09737314 chr17:6899359 ALOX12 0.47 5.19 0.42 8.17e-7 Tonsillectomy; TGCT cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2486288 0.656 rs11632419 chr15:45557456 C/A cg26924012 chr15:45694286 SPATA5L1 -0.75 -7.78 -0.57 2.39e-12 Glomerular filtration rate; TGCT cis rs4851254 0.961 rs13019618 chr2:100753963 G/T cg23118464 chr2:100721844 AFF3 0.66 5.08 0.42 1.35e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs10049627 chr4:99025272 A/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.715 rs116787789 chr4:98718720 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.99 0.41 2.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2760061 0.626 rs634106 chr1:228121548 C/T cg18477163 chr1:228402036 OBSCN -0.31 -6.24 -0.49 6.26e-9 Diastolic blood pressure; TGCT cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.87 0.47 3.78e-8 Alzheimer's disease; TGCT cis rs877282 0.838 rs11253408 chr10:796374 T/C cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs3617 0.625 rs2535633 chr3:52859630 C/G cg05573699 chr3:52720067 GNL3;PBRM1 0.47 4.6 0.38 1.02e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9985766 1.000 rs4356899 chr4:151002618 C/A cg05926478 chr4:151174724 DCLK2 -0.24 -4.72 -0.39 6.32e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg26354017 chr1:205819088 PM20D1 0.71 9.98 0.67 1.39e-17 Menarche (age at onset); TGCT cis rs367943 1.000 rs348955 chr5:112821643 C/T cg12552261 chr5:112820674 MCC -0.24 -5.01 -0.41 1.82e-6 Type 2 diabetes; TGCT cis rs7772486 0.774 rs2748503 chr6:146295042 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.56 0.38 1.2e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs208520 0.690 rs10455594 chr6:66737894 C/G cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs7666738 0.887 rs34509663 chr4:98982531 C/T cg17366294 chr4:99064904 C4orf37 0.77 7.0 0.53 1.4e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.867 rs6493085 chr15:43654182 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs10504229 0.815 rs16921955 chr8:58164553 C/T cg08280861 chr8:58055591 NA 0.36 4.58 0.38 1.11e-5 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg05785598 chr3:49045655 WDR6 0.36 4.86 0.4 3.41e-6 Menarche (age at onset); TGCT cis rs4919044 0.808 rs2478238 chr10:94805531 A/G cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT trans rs17685 0.753 rs9691174 chr7:75790405 T/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4654899 0.865 rs6426658 chr1:21361176 G/A cg01072550 chr1:21505969 NA -0.46 -6.71 -0.52 6.27e-10 Superior frontal gyrus grey matter volume; TGCT cis rs7119 0.700 rs60701760 chr15:77888152 G/A cg27398640 chr15:77910606 LINGO1 0.33 6.85 0.52 3.09e-10 Type 2 diabetes; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg22166914 chr1:53195759 ZYG11B 0.35 6.09 0.48 1.32e-8 Monocyte count; TGCT cis rs10186029 0.676 rs10497991 chr2:213968775 G/A cg08319019 chr2:214017104 IKZF2 0.63 5.79 0.46 5.4e-8 Systemic sclerosis; TGCT cis rs6722750 0.783 rs4671550 chr2:64389314 T/A cg22352474 chr2:64371530 PELI1 0.67 6.33 0.49 4.07e-9 Neuroticism; TGCT cis rs13631 0.965 rs9411307 chr9:139994947 C/T cg14289826 chr9:140003911 NA 0.26 6.07 0.48 1.44e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs758747 0.514 rs8054140 chr16:3572694 G/T cg07396092 chr16:3662230 BTBD12 0.57 4.8 0.4 4.54e-6 Body mass index; TGCT cis rs7255045 0.788 rs2290688 chr19:12958697 T/C cg11738485 chr19:12877000 HOOK2 -0.57 -4.55 -0.38 1.24e-5 Mean corpuscular volume; TGCT cis rs10504229 0.683 rs11786043 chr8:58133174 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9858542 1.000 rs11718165 chr3:49696797 A/G cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2197308 0.703 rs10880251 chr12:37903297 G/A cg26384229 chr12:38710491 ALG10B 0.89 7.98 0.58 8.43e-13 Morning vs. evening chronotype; TGCT cis rs826838 0.904 rs11612004 chr12:39204282 G/A cg13010199 chr12:38710504 ALG10B 0.77 6.09 0.48 1.31e-8 Heart rate; TGCT cis rs7010267 0.570 rs7004539 chr8:120040499 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs6540559 0.673 rs7550857 chr1:209956542 C/A cg21951975 chr1:209979733 IRF6 0.71 5.47 0.44 2.43e-7 Cleft lip with or without cleft palate; TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg04389838 chr3:44770851 ZNF501 -0.41 -5.7 -0.46 8.13e-8 Depressive symptoms; TGCT cis rs11696501 0.539 rs6073849 chr20:44299385 A/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs875971 0.660 rs10229345 chr7:65982168 G/C cg00343986 chr7:65444356 GUSB 0.22 4.71 0.39 6.59e-6 Aortic root size; TGCT cis rs6831352 0.819 rs896992 chr4:100002372 C/T cg12011299 chr4:100065546 ADH4 0.42 5.76 0.46 6.11e-8 Alcohol dependence; TGCT cis rs2147959 0.941 rs1007686 chr1:228651457 A/G cg22700015 chr1:228743131 NA -0.57 -4.48 -0.37 1.66e-5 Adult asthma; TGCT cis rs4642101 1.000 rs4642101 chr3:12842223 T/G cg05775895 chr3:12838266 CAND2 0.55 5.21 0.42 7.75e-7 QRS complex (12-leadsum); TGCT cis rs72945132 0.882 rs12278125 chr11:70134016 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs3087591 0.887 rs2905875 chr17:29541339 A/T cg24425628 chr17:29625626 OMG;NF1 0.47 7.05 0.54 1.08e-10 Hip circumference; TGCT cis rs4555082 0.957 rs2975216 chr14:105713134 T/C cg01266790 chr14:105781312 PACS2 0.52 4.49 0.37 1.61e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs78461346 1.000 rs76195156 chr17:80488094 C/T cg15014069 chr17:80540666 FOXK2 0.4 5.04 0.41 1.62e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg03806693 chr22:41940476 POLR3H -1.13 -13.24 -0.77 1.73e-25 Vitiligo; TGCT cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT trans rs7618501 0.633 rs6446193 chr3:50059758 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs909674 0.731 rs4821897 chr22:39835587 A/G cg24399712 chr22:39784796 NA -1.08 -11.12 -0.71 2.43e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7727544 0.606 rs72795121 chr5:131638324 T/A cg24060327 chr5:131705240 SLC22A5 -0.52 -5.43 -0.44 2.8e-7 Blood metabolite levels; TGCT cis rs9513627 0.512 rs9517759 chr13:100180108 T/G cg25919922 chr13:100150906 NA 0.84 6.12 0.48 1.13e-8 Obesity-related traits; TGCT cis rs6598955 0.572 rs12089219 chr1:26638751 C/T cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs3739821 1.000 rs3739821 chr9:130702477 A/G cg17308606 chr9:130706144 FAM102A 0.29 4.82 0.4 4.1e-6 Glaucoma (primary angle closure); TGCT cis rs66731853 0.769 rs477679 chr1:20894618 A/G cg01468656 chr1:19991678 HTR6 -0.43 -4.49 -0.37 1.61e-5 Mean corpuscular volume; TGCT cis rs806215 0.526 rs3808086 chr7:127539245 G/C cg11539674 chr7:127291444 SND1 -0.37 -4.74 -0.39 5.81e-6 Type 2 diabetes; TGCT cis rs9926296 0.632 rs72807526 chr16:89775946 A/G cg27121462 chr16:89883253 FANCA -0.54 -4.7 -0.39 6.86e-6 Vitiligo; TGCT cis rs6121246 0.567 rs6088796 chr20:30213229 C/T cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs881375 0.678 rs10739581 chr9:123696871 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.77 0.39 5.11e-6 Rheumatoid arthritis; TGCT cis rs765787 0.505 rs11630884 chr15:45532246 C/T cg24006582 chr15:45444508 DUOX1 -0.24 -5.28 -0.43 5.51e-7 Uric acid levels; TGCT cis rs9902453 0.934 rs11080120 chr17:28507021 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs981844 0.712 rs4632640 chr4:154742389 G/C cg14289246 chr4:154710475 SFRP2 -1.0 -9.26 -0.64 7.7e-16 Response to statins (LDL cholesterol change); TGCT cis rs1784581 0.588 rs6455790 chr6:162418447 C/T cg17173639 chr6:162384350 PARK2 -0.4 -6.6 -0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs3806843 0.576 rs246011 chr5:140336405 G/C cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs2404602 0.610 rs28823285 chr15:77050395 T/C cg23625390 chr15:77176239 SCAPER -0.38 -4.79 -0.39 4.75e-6 Blood metabolite levels; TGCT cis rs651907 0.557 rs7612283 chr3:101434919 C/T cg12386194 chr3:101231763 SENP7 0.51 4.9 0.4 2.89e-6 Colorectal cancer; TGCT cis rs2832191 0.791 rs2832198 chr21:30498240 C/T cg24692254 chr21:30365293 RNF160 0.84 8.58 0.61 3.24e-14 Dental caries; TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.72e-6 Prudent dietary pattern; TGCT cis rs4443100 0.670 rs8139280 chr22:23405957 G/A cg14186256 chr22:23484241 RTDR1 0.57 4.47 0.37 1.75e-5 Serum parathyroid hormone levels; TGCT cis rs763121 0.888 rs2235229 chr22:39124912 A/G cg06022373 chr22:39101656 GTPBP1 0.67 6.1 0.48 1.24e-8 Menopause (age at onset); TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg24503407 chr1:205819492 PM20D1 -0.53 -7.16 -0.54 6.37e-11 Monocyte percentage of white cells; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg00024416 chr22:24240387 NA -0.25 -4.74 -0.39 5.74e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2657888 0.529 rs11171863 chr12:56879548 C/T cg23002907 chr12:56915593 RBMS2 -0.38 -4.77 -0.39 5.13e-6 Adiponectin levels; TGCT cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs910187 0.678 rs1046667 chr20:45817255 A/C cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs9362426 1.000 rs6930076 chr6:88088654 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.19 0.42 8.5e-7 Depressive episodes in bipolar disorder; TGCT cis rs6840360 0.533 rs13119490 chr4:152713412 A/G cg17479576 chr4:152424074 FAM160A1 0.49 4.94 0.41 2.51e-6 Intelligence (multi-trait analysis); TGCT cis rs67311347 0.911 rs6775936 chr3:40377399 T/G cg13683864 chr3:40499215 RPL14 -1.03 -10.51 -0.69 7.36e-19 Renal cell carcinoma; TGCT cis rs2455799 0.613 rs4685260 chr3:15832417 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.75 -0.39 5.41e-6 Mean platelet volume; TGCT trans rs6089829 0.962 rs2277768 chr20:61666823 T/C cg17470723 chr8:74884337 TCEB1 0.73 7.11 0.54 8.13e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs7829975 0.774 rs1703982 chr8:8598388 A/T cg06636001 chr8:8085503 FLJ10661 -0.61 -5.29 -0.43 5.27e-7 Mood instability; TGCT cis rs12682352 0.652 rs3827806 chr8:8724276 C/T cg06636001 chr8:8085503 FLJ10661 0.68 6.25 0.49 5.99e-9 Neuroticism; TGCT cis rs9296092 0.517 rs55963187 chr6:33523778 G/C cg13560919 chr6:33536144 NA -0.2 -4.64 -0.38 8.68e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT trans rs7726839 0.794 rs11739663 chr5:594083 A/G cg11887960 chr12:57824829 NA 0.95 7.43 0.56 1.52e-11 Obesity-related traits; TGCT cis rs9583531 0.891 rs9521906 chr13:111358000 T/G cg24331049 chr13:111365604 ING1 -0.73 -4.97 -0.41 2.17e-6 Coronary artery disease; TGCT cis rs4580814 0.869 rs4535497 chr5:1107428 G/T cg13592947 chr5:1111049 SLC12A7 0.3 5.87 0.47 3.74e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs10883723 0.810 rs913025 chr10:104276043 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs909674 0.818 rs5757681 chr22:39845547 A/G cg11247378 chr22:39784982 NA -0.73 -8.79 -0.62 1.04e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6598955 0.670 rs7522905 chr1:26609259 C/T cg04990556 chr1:26633338 UBXN11 -0.9 -11.45 -0.72 3.7e-21 Obesity-related traits; TGCT cis rs9814567 1.000 rs6793487 chr3:134299426 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.91 8.83 0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1532993 0.518 rs1508464 chr4:98572205 A/C cg05340658 chr4:99064831 C4orf37 -0.42 -5.05 -0.41 1.57e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg08280861 chr8:58055591 NA 0.4 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs11105298 0.891 rs10858909 chr12:89935387 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6089829 0.962 rs6122344 chr20:61661738 C/T cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT trans rs1974653 0.672 rs1558495 chr22:20071652 T/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs67311347 1.000 rs9841335 chr3:40475858 G/A cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7264396 0.635 rs7263302 chr20:34545858 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs2836974 0.931 rs2735306 chr21:40713134 A/G cg11890956 chr21:40555474 PSMG1 -1.03 -10.04 -0.67 1.03e-17 Cognitive function; TGCT cis rs4072705 0.646 rs4838187 chr9:127242076 G/C cg13476313 chr9:127244764 NR5A1 0.29 4.75 0.39 5.54e-6 Menarche (age at onset); TGCT cis rs2019216 0.524 rs1518049 chr17:21922055 C/T cg22648282 chr17:21454238 C17orf51 -0.56 -5.45 -0.44 2.57e-7 Pelvic organ prolapse; TGCT trans rs1814175 0.754 rs10839453 chr11:49955815 A/T cg15704280 chr7:45808275 SEPT13 -0.74 -8.5 -0.61 5.05e-14 Height; TGCT cis rs9372498 0.536 rs2356501 chr6:118942371 C/A cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs589448 0.900 rs588493 chr12:69751986 G/A cg11871910 chr12:69753446 YEATS4 0.88 10.21 0.68 3.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs7208859 0.673 rs9889755 chr17:29234505 A/G cg14008862 chr17:28927542 LRRC37B2 -0.66 -4.46 -0.37 1.79e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs8038465 0.594 rs55816897 chr15:73869767 G/T cg15420318 chr15:73925796 NPTN 0.66 7.26 0.55 3.69e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17221829 0.703 rs75183199 chr11:89356987 A/G cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs1801251 0.963 rs283481 chr2:233648091 A/G cg08000102 chr2:233561755 GIGYF2 0.63 6.35 0.5 3.67e-9 Coronary artery disease; TGCT cis rs10083777 0.551 rs111889995 chr16:81033771 A/C cg07676361 chr16:80966860 NA -0.61 -4.87 -0.4 3.27e-6 Metabolite levels (small molecules and protein measures); TGCT cis rs7769051 0.711 rs7758531 chr6:133085302 T/C cg22852734 chr6:133119734 C6orf192 1.22 6.68 0.51 7.22e-10 Type 2 diabetes nephropathy; TGCT cis rs6582630 0.503 rs4882293 chr12:38388200 G/C cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.46e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.830 rs13124127 chr4:98990729 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.6 0.45 1.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg09904177 chr6:26538194 HMGN4 0.63 5.85 0.46 4.16e-8 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.545 rs2836956 chr21:40623018 C/G cg06238570 chr21:40685208 BRWD1 0.6 6.21 0.49 7.28e-9 Menarche (age at onset); TGCT cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg00343986 chr7:65444356 GUSB 0.22 5.31 0.43 4.99e-7 Calcium levels; TGCT cis rs12776158 0.901 rs61086796 chr10:71216848 T/C cg12610070 chr10:71211762 TSPAN15 -0.59 -5.17 -0.42 9.16e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs12497850 0.931 rs12493289 chr3:48905161 G/A cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs7843479 0.965 rs17616085 chr8:21857267 C/T cg17168535 chr8:21777572 XPO7 0.64 5.79 0.46 5.31e-8 Mean corpuscular volume; TGCT cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg05025164 chr4:1340916 KIAA1530 0.79 6.92 0.53 2.17e-10 Longevity; TGCT trans rs4346053 0.702 rs4347471 chr12:33116181 A/C cg06490627 chr16:50344198 ADCY7 0.44 6.82 0.52 3.61e-10 Body mass index (change over time) in lung cancer; TGCT cis rs7224685 0.569 rs67815988 chr17:3998312 A/C cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.35 0.83 9.56e-33 Prudent dietary pattern; TGCT cis rs896854 0.818 rs896855 chr8:95959808 A/G cg16049864 chr8:95962084 TP53INP1 -0.74 -10.49 -0.69 8.05e-19 Type 2 diabetes; TGCT cis rs12049351 0.719 rs10916492 chr1:229634396 G/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs265548 0.608 rs36690 chr19:17910483 C/T cg16744531 chr19:17905626 B3GNT3 0.43 5.45 0.44 2.61e-7 Tumor biomarkers; TGCT cis rs370915 0.542 rs7687552 chr4:187837862 G/C cg19519643 chr4:187840862 NA -0.23 -4.65 -0.39 8.5e-6 Gout; TGCT cis rs35306767 0.761 rs1871621 chr10:1049596 C/T cg26597838 chr10:835615 NA 0.6 6.63 0.51 9.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs3796352 1.000 rs71301809 chr3:53090312 C/T cg27565382 chr3:53032988 SFMBT1 0.43 4.6 0.38 1.01e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9796 0.870 rs10851402 chr15:41263438 C/T cg18705301 chr15:41695430 NDUFAF1 0.43 5.48 0.44 2.23e-7 Menopause (age at onset); TGCT cis rs28374715 0.617 rs28626792 chr15:41562218 A/G cg18705301 chr15:41695430 NDUFAF1 -0.65 -8.7 -0.62 1.71e-14 Ulcerative colitis; TGCT cis rs2204008 0.713 rs12366709 chr12:38210179 G/A cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg27588902 chr6:42928151 GNMT -0.57 -7.0 -0.53 1.39e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12893668 0.543 rs12147645 chr14:104100208 T/A cg26031613 chr14:104095156 KLC1 -0.59 -5.1 -0.42 1.25e-6 Reticulocyte count; TGCT cis rs7666738 0.830 rs28795113 chr4:98951331 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs58722170 0.659 rs72659423 chr1:38083472 C/T cg17933807 chr1:38061675 GNL2 -0.84 -8.42 -0.6 7.9e-14 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7267979 1.000 rs6076336 chr20:25319212 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2188554 0.740 rs6957018 chr7:117210368 C/T cg09181792 chr7:117119393 CFTR 0.52 4.68 0.39 7.3e-6 Esophageal adenocarcinoma; TGCT cis rs758129 0.501 rs3176202 chr15:89866286 G/A cg24365117 chr15:89879190 POLG 0.35 4.56 0.38 1.23e-5 Schizophrenia; TGCT cis rs79149102 0.579 rs12592477 chr15:75292699 C/T cg09165964 chr15:75287851 SCAMP5 -1.07 -5.81 -0.46 4.89e-8 Lung cancer; TGCT cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg08280861 chr8:58055591 NA 0.48 5.11 0.42 1.21e-6 Developmental language disorder (linguistic errors); TGCT cis rs950776 0.678 rs12910237 chr15:78956338 C/T cg03762349 chr15:79060523 ADAMTS7 0.25 4.87 0.4 3.35e-6 Sudden cardiac arrest; TGCT cis rs6663390 0.510 rs6693798 chr1:208090018 A/G cg03990033 chr1:208084030 CD34 0.57 4.89 0.4 3.07e-6 Facial morphology (factor 18); TGCT cis rs35000415 0.566 rs34644138 chr7:128720967 A/G cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs473651 0.935 rs482775 chr2:239335403 G/C cg18131467 chr2:239335373 ASB1 1.0 14.33 0.79 4.58e-28 Multiple system atrophy; TGCT cis rs7192750 0.652 rs152828 chr16:72123886 T/C cg14768367 chr16:72042858 DHODH 0.88 4.57 0.38 1.17e-5 LDL cholesterol levels;Total cholesterol levels; TGCT trans rs7726839 0.561 rs4957048 chr5:583442 G/A cg25482853 chr8:67687455 SGK3 1.07 8.9 0.62 5.55e-15 Obesity-related traits; TGCT cis rs9467711 0.606 rs68112369 chr6:26365759 T/C cg10795676 chr6:26370623 BTN3A2 -0.47 -4.82 -0.4 4.1e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs727505 0.954 rs2054586 chr7:124708414 C/T cg23710748 chr7:124431027 NA -0.27 -4.7 -0.39 6.77e-6 Lewy body disease; TGCT cis rs61931739 0.500 rs11053177 chr12:34412829 G/A cg06521331 chr12:34319734 NA -0.29 -4.49 -0.37 1.59e-5 Morning vs. evening chronotype; TGCT cis rs7267979 0.873 rs6115093 chr20:25210730 C/T cg03522245 chr20:25566470 NINL 0.61 6.59 0.51 1.13e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2338224 1.000 rs9293307 chr5:71746767 A/C cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs7095607 0.813 rs7894981 chr10:69927518 T/C cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.72e-6 Lung function (FVC); TGCT cis rs611744 0.967 rs677330 chr8:109177572 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs7726839 0.574 rs72705017 chr5:623733 G/A cg20362242 chr5:692897 TPPP 0.52 4.48 0.37 1.68e-5 Obesity-related traits; TGCT cis rs4713118 0.868 rs35069907 chr6:27746692 T/C cg20933634 chr6:27740509 NA 0.35 4.82 0.4 4.13e-6 Parkinson's disease; TGCT cis rs7940866 0.774 rs2162059 chr11:130831224 C/T cg12179176 chr11:130786555 SNX19 0.63 6.15 0.48 9.91e-9 Schizophrenia; TGCT cis rs12681288 0.645 rs2600509 chr8:989022 C/G cg04851639 chr8:1020857 NA 0.3 4.88 0.4 3.22e-6 Schizophrenia; TGCT trans rs8073060 0.586 rs226084 chr17:34019582 T/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg23205692 chr1:25664452 TMEM50A 0.5 5.14 0.42 1.05e-6 Erythrocyte sedimentation rate; TGCT cis rs2012796 0.956 rs56223983 chr14:81814754 G/T cg02996355 chr14:81879375 NA 0.5 4.82 0.4 4.2e-6 Night sleep phenotypes; TGCT cis rs2455799 0.533 rs924754 chr3:15756215 A/T cg16303742 chr3:15540471 COLQ -0.26 -4.84 -0.4 3.75e-6 Mean platelet volume; TGCT cis rs66573146 0.831 rs67702333 chr4:6983040 C/G cg05069807 chr4:6945702 TBC1D14 0.32 5.01 0.41 1.83e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs611744 0.647 rs615233 chr8:109254262 C/T cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs3784262 0.654 rs4646568 chr15:58344290 A/G cg12031962 chr15:58353849 ALDH1A2 0.52 8.25 0.6 1.98e-13 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9291683 0.935 rs1860910 chr4:10275470 T/G cg00071950 chr4:10020882 SLC2A9 0.42 4.58 0.38 1.13e-5 Bone mineral density; TGCT cis rs9322193 0.923 rs9478291 chr6:150050570 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg20607798 chr8:58055168 NA 0.53 4.54 0.38 1.3e-5 Developmental language disorder (linguistic errors); TGCT cis rs4499344 0.633 rs259246 chr19:33146154 G/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 9.01 0.63 3.11e-15 Mean platelet volume; TGCT cis rs4988958 0.525 rs3771159 chr2:103004958 T/C cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma (childhood onset); TGCT trans rs941408 0.963 rs1640268 chr19:2791469 T/C cg22153745 chr1:153894579 GATAD2B -0.65 -7.35 -0.55 2.39e-11 Total cholesterol levels; TGCT cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg18252515 chr7:66147081 NA -1.24 -8.1 -0.59 4.35e-13 Diabetic kidney disease; TGCT cis rs611744 0.967 rs662591 chr8:109211358 C/T cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7666738 0.830 rs2019163 chr4:99022747 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.06 0.54 1.04e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg07507251 chr3:52567010 NT5DC2 0.46 6.47 0.5 2.04e-9 Bipolar disorder; TGCT cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs548987 0.507 rs3757132 chr6:25832691 C/T cg03517284 chr6:25882590 NA -0.56 -4.56 -0.38 1.22e-5 Homocysteine levels; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs476633 0.573 rs2099652 chr15:41528745 C/G cg18705301 chr15:41695430 NDUFAF1 -0.68 -8.54 -0.61 3.98e-14 Glomerular filtration rate (creatinine); TGCT cis rs875971 0.862 rs11760844 chr7:65739883 C/G cg11764359 chr7:65958608 NA -0.57 -5.12 -0.42 1.12e-6 Aortic root size; TGCT cis rs9811920 0.625 rs9290003 chr3:99906993 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.41 -4.83 -0.4 3.89e-6 Axial length; TGCT cis rs12477438 0.765 rs7607578 chr2:99669771 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs2576037 0.583 rs11659693 chr18:44458733 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT trans rs2469997 1.000 rs2447174 chr8:120358571 G/A cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs12620999 0.555 rs4663242 chr2:238102905 C/T cg23555395 chr2:238036564 NA -0.26 -4.45 -0.37 1.88e-5 Systemic lupus erythematosus; TGCT trans rs804280 0.509 rs12719915 chr8:11786255 A/G cg15556689 chr8:8085844 FLJ10661 -0.76 -7.27 -0.55 3.59e-11 Myopia (pathological); TGCT cis rs916888 0.779 rs199528 chr17:44843136 C/T cg01570182 chr17:44337453 NA 1.01 9.34 0.64 4.88e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7399018 0.739 rs6580811 chr12:51612501 T/C cg25754956 chr12:51612065 POU6F1 0.94 8.81 0.62 9.47e-15 Cisplatin-induced ototoxicity; TGCT cis rs67311347 0.521 rs2887963 chr3:40243466 C/T cg13683864 chr3:40499215 RPL14 0.64 5.92 0.47 2.94e-8 Renal cell carcinoma; TGCT cis rs617219 0.698 rs13177470 chr5:78495899 T/C cg23987322 chr5:78407566 BHMT 0.38 5.07 0.41 1.39e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4803468 1.000 rs284651 chr19:41928336 T/C cg09537434 chr19:41945824 ATP5SL -0.91 -10.16 -0.67 5.26e-18 Height; TGCT cis rs9964724 0.559 rs7243439 chr18:35156196 A/G cg27332583 chr18:35150602 NA 0.3 4.63 0.38 9.19e-6 Educational attainment (years of education); TGCT cis rs3772130 0.962 rs9883467 chr3:121517833 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs7647973 0.626 rs1463728 chr3:49647404 T/A cg03060546 chr3:49711283 APEH 0.65 5.26 0.43 6.07e-7 Menarche (age at onset); TGCT cis rs2242194 0.844 rs11264295 chr1:154987526 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.55 -5.05 -0.41 1.53e-6 Schizophrenia; TGCT cis rs7659604 0.539 rs11098648 chr4:122759872 C/T cg06713675 chr4:122721982 EXOSC9 -0.68 -9.18 -0.64 1.23e-15 Type 2 diabetes; TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg21548813 chr6:291882 DUSP22 -0.72 -7.59 -0.56 6.53e-12 Menopause (age at onset); TGCT cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg23205692 chr1:25664452 TMEM50A 0.47 4.88 0.4 3.15e-6 Erythrocyte sedimentation rate; TGCT cis rs9419702 0.568 rs7075233 chr10:133545170 A/G cg20568497 chr10:133558893 NA -0.47 -5.36 -0.43 3.87e-7 Survival in rectal cancer; TGCT cis rs1395 0.710 rs11674947 chr2:27471996 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT trans rs2610739 0.554 rs9353574 chr6:89223576 G/A cg05764691 chr16:22927585 HS3ST2 0.4 6.62 0.51 9.76e-10 IgG glycosylation; TGCT cis rs7336332 0.891 rs927578 chr13:28075022 G/T cg22138327 chr13:27999177 GTF3A 0.83 5.89 0.47 3.34e-8 Weight; TGCT cis rs12497850 0.805 rs11130176 chr3:48844077 A/G cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs1401999 0.510 rs12634398 chr3:183708405 A/G cg01324343 chr3:183735012 ABCC5 0.52 5.66 0.45 9.97e-8 Anterior chamber depth; TGCT cis rs4819052 0.851 rs28622522 chr21:46676599 G/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg08048268 chr3:133502702 NA -0.53 -7.17 -0.54 5.89e-11 Iron status biomarkers; TGCT cis rs7617773 0.744 rs2125482 chr3:48323133 T/G cg11946769 chr3:48343235 NME6 0.72 6.12 0.48 1.14e-8 Coronary artery disease; TGCT cis rs6988636 0.710 rs73339621 chr8:124138936 C/T cg23067535 chr8:124195133 FAM83A -0.38 -4.8 -0.4 4.53e-6 Urinary uromodulin levels; TGCT cis rs7666738 0.791 rs13149968 chr4:99070262 G/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs35306767 0.903 rs12240651 chr10:943656 A/G cg26597838 chr10:835615 NA 0.76 10.69 0.69 2.61e-19 Eosinophil percentage of granulocytes; TGCT cis rs7246657 0.943 rs9304566 chr19:37845504 T/C cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs868036 0.609 rs2278076 chr15:68099600 C/T cg27219399 chr15:67835830 MAP2K5 0.34 4.49 0.37 1.6e-5 Restless legs syndrome; TGCT cis rs11997175 0.599 rs66474258 chr8:33640225 A/T ch.8.33884649F chr8:33765107 NA 0.28 4.45 0.37 1.87e-5 Body mass index; TGCT cis rs1008375 0.800 rs62296338 chr4:17613425 G/T cg18681998 chr4:17616180 MED28 1.05 10.97 0.7 5.56e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs561341 1.000 rs8069199 chr17:30281845 A/G cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs9790314 0.871 rs336551 chr3:161109720 T/C cg03342759 chr3:160939853 NMD3 -0.49 -5.13 -0.42 1.08e-6 Morning vs. evening chronotype; TGCT cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.55 -6.53 -0.51 1.5e-9 Alzheimer's disease; TGCT cis rs1461503 0.966 rs10892937 chr11:122841904 T/C cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs7267979 1.000 rs6050631 chr20:25431749 C/T cg14121845 chr20:25566513 NINL 0.51 5.47 0.44 2.35e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6460942 0.915 rs62447639 chr7:12486803 T/C cg06484146 chr7:12443880 VWDE -0.61 -5.43 -0.44 2.87e-7 Coronary artery disease; TGCT cis rs4689388 0.890 rs4689398 chr4:6302199 C/T cg25554036 chr4:6271136 WFS1 0.56 7.96 0.58 9.38e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7914558 0.966 rs1591915 chr10:104646849 C/T cg15744005 chr10:104629667 AS3MT -0.41 -5.09 -0.42 1.29e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6582630 0.559 rs12318620 chr12:38522340 T/C cg26384229 chr12:38710491 ALG10B -0.55 -4.89 -0.4 3.05e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9357506 0.935 rs11963572 chr6:46302448 T/C cg21115430 chr6:46460003 NA -0.25 -5.16 -0.42 9.35e-7 Body mass index; TGCT cis rs2115630 1.000 rs6496441 chr15:85363348 A/G cg11189052 chr15:85197271 WDR73 -0.61 -5.7 -0.46 8.1e-8 P wave terminal force; TGCT cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg21016266 chr12:122356598 WDR66 0.43 5.67 0.45 9.63e-8 Mean corpuscular volume; TGCT cis rs2692947 0.537 rs12478605 chr2:96377078 C/T cg23100626 chr2:96804247 ASTL 0.47 5.57 0.45 1.48e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9399135 0.904 rs4895438 chr6:135317665 G/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs12134133 1.000 rs4844590 chr1:207496129 C/T cg02152968 chr1:207494213 CD55 0.6 4.47 0.37 1.74e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT trans rs8073060 0.544 rs225287 chr17:33929487 G/T cg19694781 chr19:47549865 TMEM160 -0.59 -12.83 -0.76 1.67e-24 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2637266 1.000 rs10824431 chr10:78356622 C/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs6433857 0.505 rs7561255 chr2:181369216 A/G cg23363182 chr2:181467187 NA -0.33 -4.98 -0.41 2.05e-6 Body mass index; TGCT cis rs7542091 0.637 rs9429826 chr1:210052146 G/A cg21951975 chr1:209979733 IRF6 0.58 5.87 0.47 3.81e-8 Monobrow; TGCT cis rs6459788 0.693 rs35146559 chr7:157238557 G/A cg06271696 chr7:157225062 NA -0.29 -5.13 -0.42 1.07e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs4622507 0.728 rs34585830 chr16:55054891 G/T cg04853843 chr16:55358461 IRX6 -0.52 -4.71 -0.39 6.42e-6 Social communication problems; TGCT cis rs25422 0.938 rs62421538 chr6:118729703 A/T cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Renal cell carcinoma; TGCT cis rs670523 0.596 rs72708239 chr1:155985899 A/G cg13795986 chr1:155880507 RIT1 0.37 4.48 0.37 1.66e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg24846343 chr22:24311635 DDTL 0.25 6.34 0.49 3.97e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2243480 1.000 rs34136756 chr7:65381256 A/G cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg10819733 chr22:24237672 NA -0.32 -5.59 -0.45 1.39e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6740322 0.901 rs2163228 chr2:43549246 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.35 -5.21 -0.42 7.74e-7 Coronary artery disease; TGCT cis rs6547741 1.000 rs7604798 chr2:27824940 T/C cg27432699 chr2:27873401 GPN1 0.18 4.65 0.38 8.53e-6 Oral cavity cancer; TGCT cis rs73001065 0.591 rs2285626 chr19:19467545 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.71 4.49 0.37 1.62e-5 LDL cholesterol; TGCT cis rs7714584 1.000 rs6579803 chr5:150255559 C/T cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs13064411 0.696 rs11921931 chr3:113015091 G/A cg18753928 chr3:113234510 CCDC52 -0.7 -5.01 -0.41 1.8e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs240764 0.658 rs35967345 chr6:101187858 T/G cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs42648 0.869 rs42613 chr7:89950303 C/T cg25739043 chr7:89950458 NA -0.73 -7.29 -0.55 3.2e-11 Homocysteine levels; TGCT cis rs6684514 1.000 rs11264467 chr1:156273061 A/G cg20302342 chr1:156215951 PAQR6 -0.36 -4.73 -0.39 6.11e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs8067545 1.000 rs8065337 chr17:19941879 C/A cg13482628 chr17:19912719 NA 0.54 4.73 0.39 5.94e-6 Schizophrenia; TGCT cis rs4494114 0.967 rs6696437 chr1:39348165 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.23 -0.49 6.58e-9 Blood protein levels; TGCT cis rs7618915 1.000 rs3852064 chr3:52349412 G/T cg10802521 chr3:52805072 NEK4 -0.54 -5.74 -0.46 6.9e-8 Bipolar disorder; TGCT cis rs2721195 0.654 rs4610795 chr8:145881333 C/T cg15320075 chr8:145703422 NA -0.61 -5.66 -0.45 1.01e-7 Age at first birth; TGCT cis rs9300255 0.679 rs10772998 chr12:123721177 T/G cg00376283 chr12:123451042 ABCB9 0.72 5.59 0.45 1.35e-7 Neutrophil percentage of white cells; TGCT cis rs6964587 0.626 rs2269810 chr7:91508837 T/C cg17063962 chr7:91808500 NA -0.75 -7.02 -0.53 1.25e-10 Breast cancer; TGCT cis rs5769765 0.542 rs5769751 chr22:50242733 T/G cg22709217 chr22:50311962 ALG12;CRELD2 1.07 5.7 0.46 8.46e-8 Schizophrenia; TGCT cis rs80033912 0.626 rs71324982 chr3:49669948 G/A cg12257692 chr3:49977190 RBM6 0.27 4.8 0.4 4.4e-6 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.697 rs6120970 chr20:30232452 C/T cg18721089 chr20:30220636 NA -0.53 -5.43 -0.44 2.86e-7 Mean corpuscular hemoglobin; TGCT cis rs28595532 0.920 rs10001115 chr4:119781867 A/C cg00700008 chr4:120138107 USP53 0.49 4.48 0.37 1.71e-5 Cannabis dependence symptom count; TGCT cis rs977747 0.872 rs10890471 chr1:47676525 C/A cg03885399 chr1:47691550 TAL1 -0.42 -5.48 -0.44 2.27e-7 Body mass index; TGCT cis rs7513165 0.736 rs4889 chr1:204159787 G/C cg12731349 chr1:204159619 KISS1 0.49 5.62 0.45 1.19e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs7014346 0.767 rs10956367 chr8:128423544 T/C cg04263511 chr8:128962092 PVT1 -0.31 -4.55 -0.38 1.25e-5 Colorectal cancer; TGCT cis rs6563842 0.528 rs56340348 chr13:41296371 C/T cg21288729 chr13:41239152 FOXO1 0.94 9.1 0.63 1.87e-15 Eosinophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs7043114 0.525 rs7045409 chr9:95201540 A/T cg14631576 chr9:95140430 CENPP -0.28 -4.67 -0.39 7.71e-6 Height; TGCT cis rs11711311 1.000 rs62268169 chr3:113493860 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.38 -0.55 2e-11 IgG glycosylation; TGCT trans rs9388451 0.874 rs9398787 chr6:126090608 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.38 -0.6 9.81e-14 Brugada syndrome; TGCT cis rs2274471 0.645 rs12237834 chr9:5093646 C/T cg03390472 chr9:5043263 JAK2 -0.29 -4.68 -0.39 7.53e-6 Crohn's disease; TGCT cis rs11252926 0.598 rs4881256 chr10:453831 T/A cg18196295 chr10:418757 DIP2C 0.3 4.78 0.39 4.82e-6 Psychosis in Alzheimer's disease; TGCT cis rs875971 1.000 rs778722 chr7:65844828 T/C cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT trans rs7726839 0.526 rs11960158 chr5:568665 C/T cg11887960 chr12:57824829 NA 1.02 7.74 0.57 3.07e-12 Obesity-related traits; TGCT cis rs8017423 0.935 rs4904661 chr14:90729332 T/C cg04374321 chr14:90722782 PSMC1 0.76 7.46 0.56 1.35e-11 Mortality in heart failure; TGCT cis rs6740322 0.644 rs11690918 chr2:43474112 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.01 -0.48 1.87e-8 Coronary artery disease; TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg08736216 chr1:53307985 ZYG11A -0.23 -4.55 -0.38 1.24e-5 Monocyte count; TGCT cis rs9303401 0.659 rs62083525 chr17:56658088 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs9926296 0.593 rs6500456 chr16:89888341 T/C cg04287289 chr16:89883240 FANCA 0.7 7.06 0.54 1.05e-10 Vitiligo; TGCT cis rs9486719 1.000 rs12205655 chr6:96891733 T/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs12682352 0.602 rs4841044 chr8:8664940 A/G cg06636001 chr8:8085503 FLJ10661 -0.62 -5.42 -0.44 3.03e-7 Neuroticism; TGCT cis rs6665290 0.669 rs3738725 chr1:227174210 T/C cg10327440 chr1:227177885 CDC42BPA -0.91 -15.21 -0.81 4.04e-30 Myeloid white cell count; TGCT cis rs9303401 0.614 rs34678056 chr17:57177549 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs7772486 0.875 rs2814874 chr6:146305895 C/T cg23711669 chr6:146136114 FBXO30 0.88 9.48 0.65 2.31e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs3749237 0.964 rs2352967 chr3:49871641 C/T cg10152585 chr3:50297680 NA 0.52 4.97 0.41 2.17e-6 Resting heart rate; TGCT cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg12310025 chr6:25882481 NA -0.67 -6.09 -0.48 1.32e-8 Intelligence (multi-trait analysis); TGCT cis rs4523957 0.690 rs11078855 chr17:2091308 A/G cg16513277 chr17:2031491 SMG6 0.2 4.6 0.38 1.05e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11650494 0.908 rs78208413 chr17:47398282 G/A cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs3617 0.539 rs11922975 chr3:52936763 C/T cg11645453 chr3:52864694 ITIH4 -0.28 -5.37 -0.43 3.77e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7980687 0.628 rs1727332 chr12:123718301 C/T cg00376283 chr12:123451042 ABCB9 0.75 6.4 0.5 2.89e-9 Height;Educational attainment;Head circumference (infant); TGCT cis rs72781680 0.752 rs72796110 chr2:23905658 T/A cg08917208 chr2:24149416 ATAD2B 1.0 5.56 0.45 1.59e-7 Lymphocyte counts; TGCT cis rs5769765 0.773 rs58375955 chr22:50312630 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs6061231 0.546 rs482220 chr20:60927482 G/A cg24112000 chr20:60950667 NA 0.34 4.76 0.39 5.24e-6 Colorectal cancer; TGCT cis rs3784262 0.564 rs12148652 chr15:58198091 A/G cg12031962 chr15:58353849 ALDH1A2 0.51 6.72 0.52 5.9e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg16414030 chr3:133502952 NA 0.49 6.95 0.53 1.8e-10 Iron status biomarkers; TGCT cis rs1903068 0.719 rs17711225 chr4:55999185 G/A cg16572876 chr4:56024045 NA 0.44 4.74 0.39 5.7e-6 Endometriosis; TGCT cis rs950776 0.518 rs4887063 chr15:78839715 C/T cg21242079 chr15:79101063 ADAMTS7 0.27 4.46 0.37 1.79e-5 Sudden cardiac arrest; TGCT cis rs1691799 0.899 rs1168300 chr12:66736467 C/A cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg26531700 chr6:26746687 NA 0.51 4.61 0.38 9.86e-6 Intelligence (multi-trait analysis); TGCT cis rs1158570 0.778 rs7817803 chr8:131319822 A/C cg16277922 chr8:131349729 ASAP1 0.47 7.12 0.54 7.62e-11 Platelet count; TGCT cis rs4595586 0.545 rs9669705 chr12:39374459 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7772486 0.719 rs702307 chr6:145993454 C/G cg13319975 chr6:146136371 FBXO30 0.56 5.03 0.41 1.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6665290 0.566 rs1513617 chr1:227447213 C/T cg10327440 chr1:227177885 CDC42BPA 0.56 5.83 0.46 4.5e-8 Myeloid white cell count; TGCT cis rs3087591 1.000 rs7214792 chr17:29460673 G/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.3 0.55 3.03e-11 Hip circumference; TGCT cis rs12791968 0.917 rs11038238 chr11:45002010 A/G cg11846598 chr11:44996168 LOC221122 -0.35 -6.45 -0.5 2.29e-9 Inhibitory control; TGCT trans rs7618501 0.521 rs55692411 chr3:49911155 G/A cg21659725 chr3:3221576 CRBN 0.73 8.19 0.59 2.76e-13 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs10504229 chr8:58196495 A/G cg24829409 chr8:58192753 C8orf71 -0.55 -4.74 -0.39 5.83e-6 Developmental language disorder (linguistic errors); TGCT cis rs1865760 1.000 rs6938233 chr6:25914077 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.19 0.49 8.16e-9 Height; TGCT cis rs12477438 0.520 rs2516830 chr2:99773702 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs11534004 0.514 rs10500037 chr7:113707787 T/C cg21852992 chr7:112726869 GPR85 0.36 4.95 0.41 2.33e-6 Schizophrenia; TGCT cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.62 -0.38 9.52e-6 Obesity-related traits; TGCT trans rs9388451 0.657 rs4895799 chr6:126052729 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.74 -7.27 -0.55 3.49e-11 Brugada syndrome; TGCT cis rs2576037 0.583 rs646128 chr18:44397691 A/C cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.68 -0.39 7.48e-6 Personality dimensions; TGCT cis rs853679 0.517 rs7755442 chr6:28039015 T/C cg12963246 chr6:28129442 ZNF389 0.51 4.97 0.41 2.19e-6 Depression; TGCT cis rs67460515 0.892 rs6780536 chr3:161058726 T/C cg03342759 chr3:160939853 NMD3 -0.53 -5.88 -0.47 3.6e-8 Parkinson's disease; TGCT cis rs4727027 0.933 rs1058059 chr7:148879134 A/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.77 0.39 5.16e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs75686122 0.892 rs12156411 chr8:104716477 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs2637266 0.967 rs12246605 chr10:78352994 G/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs9457247 1.000 rs932644 chr6:167404187 A/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs17221829 0.932 rs10830358 chr11:89452943 T/A cg02982614 chr11:89391479 FOLH1B -0.29 -4.97 -0.41 2.16e-6 Anxiety in major depressive disorder; TGCT cis rs7412746 0.658 rs7521719 chr1:150913134 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs7611238 0.560 rs2275519 chr3:195022534 G/T cg27323046 chr3:195102265 ACAP2 0.35 4.68 0.39 7.5e-6 Body mass index; TGCT cis rs9611565 0.512 rs2050033 chr22:42159229 G/T cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs9894429 0.646 rs9905639 chr17:79614154 A/G cg21028142 chr17:79581711 NPLOC4 0.31 6.7 0.52 6.63e-10 Eye color traits; TGCT cis rs8180040 0.966 rs3736177 chr3:47451411 C/T cg27129171 chr3:47204927 SETD2 -0.64 -7.35 -0.55 2.39e-11 Colorectal cancer; TGCT cis rs4747241 1.000 rs12768834 chr10:74043874 A/G cg09661010 chr10:73848153 SPOCK2 0.4 4.46 0.37 1.8e-5 Heschl's gyrus morphology; TGCT cis rs6570726 0.738 rs7746330 chr6:145899257 A/C cg23711669 chr6:146136114 FBXO30 0.89 9.85 0.66 2.95e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2013441 1.000 rs2526464 chr17:20075052 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs72627509 0.767 rs6853156 chr4:57774843 C/T cg26694713 chr4:57773883 REST 0.72 6.46 0.5 2.14e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6687430 0.543 rs7512495 chr1:10631237 C/T cg17425144 chr1:10567563 PEX14 0.48 5.2 0.42 7.84e-7 Hand grip strength; TGCT cis rs28595532 0.920 rs116791817 chr4:119763303 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs115056730 0.520 rs113247402 chr2:98168573 T/C cg26665480 chr2:98280029 ACTR1B -0.96 -4.48 -0.37 1.67e-5 Monocyte chemoattractant protein-3 levels; TGCT cis rs2836974 0.965 rs34578707 chr21:40675167 G/A cg11890956 chr21:40555474 PSMG1 1.03 10.71 0.69 2.36e-19 Cognitive function; TGCT cis rs61990749 0.597 rs10142722 chr14:78275549 A/T cg02301378 chr14:78227641 SNW1;C14orf178 0.65 4.74 0.39 5.79e-6 Fibroblast growth factor basic levels; TGCT cis rs13315871 1.000 rs9869276 chr3:58401076 G/A cg12435725 chr3:58293450 RPP14 -0.44 -4.5 -0.37 1.57e-5 Cholesterol, total; TGCT cis rs2832191 0.791 rs7282843 chr21:30475226 A/G cg24692254 chr21:30365293 RNF160 0.94 10.58 0.69 4.82e-19 Dental caries; TGCT cis rs1847202 0.859 rs13090900 chr3:72946560 C/A cg25664220 chr3:72788482 NA -0.36 -4.48 -0.37 1.69e-5 Motion sickness; TGCT cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs6543140 0.964 rs13390895 chr2:103075499 G/A cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs639012 0.503 rs7114401 chr11:85839935 C/T cg07180834 chr11:85838833 NA -0.31 -4.57 -0.38 1.17e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs951366 0.903 rs708723 chr1:205739266 C/T cg24503407 chr1:205819492 PM20D1 0.43 5.25 0.43 6.31e-7 Menarche (age at onset); TGCT cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.53 4.45 0.37 1.91e-5 Height; TGCT cis rs858239 0.699 rs1881200 chr7:23201637 T/C cg05602783 chr7:23145260 KLHL7 0.68 5.64 0.45 1.1e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9457247 0.967 rs428805 chr6:167403132 C/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs9952991 0.608 rs9960807 chr18:12770851 A/G cg23598886 chr18:12777645 NA -0.71 -5.52 -0.44 1.86e-7 Inflammatory skin disease; TGCT cis rs56011263 0.687 rs11734460 chr4:705074 C/T cg20735989 chr4:730612 PCGF3 -0.24 -5.43 -0.44 2.86e-7 White blood cell count; TGCT cis rs2576037 0.562 rs13381557 chr18:44513371 A/G cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.63 -0.38 9.02e-6 Personality dimensions; TGCT cis rs514406 0.505 rs440871 chr1:53173052 C/T cg22166914 chr1:53195759 ZYG11B 0.44 7.81 0.57 2.06e-12 Monocyte count; TGCT cis rs6570726 0.791 rs13202312 chr6:145913093 T/G cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7312933 0.558 rs11181501 chr12:42822671 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.14 0.42 1.06e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7267979 0.903 rs6115109 chr20:25239667 G/A cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7208859 0.673 rs9899349 chr17:29200122 C/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg08048268 chr3:133502702 NA -0.68 -10.61 -0.69 4.08e-19 Iron status biomarkers; TGCT cis rs4711350 0.834 rs9461905 chr6:33721933 T/C cg18005901 chr6:33739558 LEMD2 -0.46 -5.04 -0.41 1.62e-6 Schizophrenia; TGCT trans rs28735056 0.584 rs11664834 chr18:77644876 G/T cg05926928 chr17:57297772 GDPD1 0.88 9.52 0.65 1.86e-16 Schizophrenia; TGCT cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg03264133 chr6:25882463 NA -0.51 -5.36 -0.43 3.84e-7 Blood metabolite levels; TGCT cis rs733175 0.857 rs3796838 chr4:10011030 C/T cg11266682 chr4:10021025 SLC2A9 0.52 4.68 0.39 7.48e-6 Psychosis and Alzheimer's disease; TGCT cis rs2742417 0.603 rs7631818 chr3:45775931 A/T cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg25767906 chr1:53392781 SCP2 -0.61 -7.43 -0.56 1.51e-11 Monocyte count; TGCT cis rs6912958 0.516 rs242278 chr6:88047059 C/T cg04972856 chr6:88032051 C6orf162;GJB7 0.4 4.71 0.39 6.65e-6 Monocyte percentage of white cells; TGCT cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs2858942 0.602 rs1211375 chr16:240280 G/T cg00126636 chr16:237282 NA 0.18 4.57 0.38 1.16e-5 Mean corpuscular hemoglobin; TGCT cis rs79349575 0.811 rs60708039 chr17:46999373 C/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs6545883 0.894 rs1186703 chr2:61672965 A/C cg15711740 chr2:61764176 XPO1 -0.57 -5.1 -0.42 1.25e-6 Tuberculosis; TGCT cis rs908922 0.676 rs11205014 chr1:152483634 C/T cg20991723 chr1:152506922 NA 0.47 6.63 0.51 9.06e-10 Hair morphology; TGCT cis rs7819412 0.522 rs11776603 chr8:11020313 G/T cg21775007 chr8:11205619 TDH -0.53 -4.65 -0.39 8.31e-6 Triglycerides; TGCT cis rs4478858 0.735 rs6679393 chr1:31770944 T/C cg00250761 chr1:31883323 NA -0.28 -5.01 -0.41 1.86e-6 Alcohol dependence; TGCT cis rs9534288 0.797 rs1319712 chr13:46591707 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs3733585 0.725 rs6449201 chr4:9973894 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.68 -0.57 4.13e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6426551 1.000 rs6668851 chr1:226545866 C/A cg18564989 chr1:226411057 MIXL1 -0.48 -4.75 -0.39 5.42e-6 Coronary artery disease; TGCT cis rs826838 0.510 rs17523988 chr12:39222785 A/C cg13010199 chr12:38710504 ALG10B 0.6 4.7 0.39 6.75e-6 Heart rate; TGCT cis rs7586879 0.638 rs10203482 chr2:25136916 T/C cg15423357 chr2:25149977 NA 0.5 4.84 0.4 3.71e-6 Body mass index; TGCT cis rs6088590 1.000 rs6119512 chr20:33306904 T/C cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs11148252 0.553 rs2147692 chr13:53287023 C/G cg02158880 chr13:53174818 NA 0.43 5.1 0.42 1.26e-6 Lewy body disease; TGCT trans rs17685 0.753 rs1104878 chr7:75685593 G/T cg19862616 chr7:65841803 NCRNA00174 0.52 8.84 0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7582180 0.764 rs11689439 chr2:100925399 T/C cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs8051431 0.806 rs7205297 chr16:72025531 C/T cg06353428 chr16:71660113 MARVELD3 0.59 4.91 0.4 2.84e-6 LDL cholesterol levels; TGCT cis rs1034435 0.755 rs5767171 chr22:48891881 A/G cg05992904 chr22:48892994 FAM19A5 -0.33 -4.52 -0.38 1.41e-5 Late-onset Alzheimer's disease; TGCT cis rs7666738 0.830 rs10031292 chr4:99056877 A/G cg17366294 chr4:99064904 C4orf37 0.72 7.25 0.55 3.95e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs838147 0.508 rs507766 chr19:49208543 T/C cg04599840 chr19:48886497 KDELR1 0.23 4.74 0.39 5.83e-6 Dietary macronutrient intake; TGCT cis rs67478160 0.609 rs1547604 chr14:104270659 A/T cg26031613 chr14:104095156 KLC1 -0.64 -6.42 -0.5 2.64e-9 Schizophrenia; TGCT cis rs4727443 0.866 rs12531809 chr7:99620473 G/T cg13334819 chr7:99746414 C7orf59 0.56 4.71 0.39 6.63e-6 Interstitial lung disease; TGCT cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg06238570 chr21:40685208 BRWD1 0.69 6.39 0.5 3.07e-9 Cognitive function; TGCT cis rs7727544 0.735 rs272875 chr5:131674888 T/C cg24060327 chr5:131705240 SLC22A5 -0.56 -6.34 -0.5 3.8e-9 Blood metabolite levels; TGCT cis rs950169 0.959 rs12911210 chr15:84792083 A/C cg17173187 chr15:85201210 NMB 0.52 5.86 0.47 3.98e-8 Schizophrenia; TGCT cis rs2816958 0.803 rs2821335 chr1:200094786 T/C cg07971716 chr1:199773294 NA 0.46 4.52 0.38 1.45e-5 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs2404602 0.655 rs8028294 chr15:77084877 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs57221529 0.766 rs72706606 chr5:558609 T/C cg09021430 chr5:549028 NA -0.4 -5.46 -0.44 2.44e-7 Lung disease severity in cystic fibrosis; TGCT cis rs9467711 0.606 rs9379871 chr6:26375854 C/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4689592 0.622 rs2276968 chr4:7070118 T/G cg02503808 chr4:7069936 GRPEL1 1.05 10.21 0.68 3.94e-18 Monocyte percentage of white cells; TGCT cis rs7412746 0.658 rs1546376 chr1:150937661 A/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.7 0.39 6.76e-6 Melanoma; TGCT cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg13409248 chr3:40428643 ENTPD3 0.55 4.49 0.37 1.61e-5 Renal cell carcinoma; TGCT cis rs7524258 0.868 rs11120885 chr1:7306755 C/G cg07173049 chr1:7289937 CAMTA1 0.29 4.74 0.39 5.72e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs1865760 0.566 rs2032443 chr6:26046802 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.31 0.55 2.87e-11 Height; TGCT cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7727544 0.816 rs274555 chr5:131722951 C/T cg00255919 chr5:131827918 IRF1 0.2 4.85 0.4 3.7e-6 Blood metabolite levels; TGCT cis rs17345786 0.906 rs72940399 chr3:101122575 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs6699043 chr1:154913021 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.19 -0.54 5.48e-11 Prostate cancer; TGCT cis rs25422 0.938 rs62422193 chr6:118912285 G/A cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Renal cell carcinoma; TGCT cis rs12479064 0.724 rs28369945 chr2:100080928 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.7 -5.87 -0.47 3.79e-8 Chronic sinus infection; TGCT cis rs1355023 0.547 rs9399943 chr6:106228922 C/T cg17356964 chr6:106582638 NA 0.26 4.92 0.4 2.7e-6 Age-related macular degeneration; TGCT cis rs2455799 0.559 rs2166761 chr3:15914838 G/A cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs2153535 0.580 rs9405390 chr6:8466209 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs35306767 0.714 rs67205460 chr10:1090366 C/T cg26597838 chr10:835615 NA 0.61 7.09 0.54 8.8e-11 Eosinophil percentage of granulocytes; TGCT cis rs2637266 0.935 rs1907299 chr10:78325316 T/C cg18941641 chr10:78392320 NA 0.42 5.38 0.43 3.6e-7 Pulmonary function; TGCT cis rs6840360 0.642 rs6843639 chr4:152416015 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs4822044 0.560 rs7284839 chr22:42010902 C/T cg06634786 chr22:41940651 POLR3H 0.89 8.56 0.61 3.56e-14 Cannabis dependence symptom count; TGCT cis rs11122272 0.701 rs743120 chr1:231531232 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -6.35 -0.5 3.66e-9 Hemoglobin concentration; TGCT cis rs73198271 0.729 rs67653033 chr8:8605044 G/C ch.8.214553F chr8:8189620 PRAGMIN -0.28 -4.79 -0.4 4.63e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2075371 0.611 rs11762920 chr7:134018514 C/T cg11752832 chr7:134001865 SLC35B4 0.63 5.1 0.42 1.23e-6 Mean platelet volume; TGCT cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg09177884 chr7:1199841 ZFAND2A -0.5 -4.84 -0.4 3.82e-6 Longevity;Endometriosis; TGCT cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg05985448 chr10:134359359 INPP5A 0.23 4.99 0.41 2.01e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs9902453 0.904 rs12939344 chr17:28328819 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -7.56 -0.56 7.78e-12 Coffee consumption (cups per day); TGCT cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.63 0.51 9.08e-10 Electroencephalogram traits; TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.45 0.56 1.42e-11 Prudent dietary pattern; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg27535305 chr1:53392650 SCP2 -0.26 -4.97 -0.41 2.16e-6 Monocyte count; TGCT cis rs2070488 1.000 rs7433707 chr3:38443180 G/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.66 0.66 8.43e-17 Electrocardiographic conduction measures; TGCT cis rs9329221 0.905 rs13252982 chr8:10255105 C/G cg21775007 chr8:11205619 TDH -0.53 -4.8 -0.4 4.5e-6 Neuroticism; TGCT cis rs2463822 1.000 rs951677 chr11:62107249 G/C cg06239285 chr11:62104954 ASRGL1 0.95 6.56 0.51 1.33e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs6545883 0.894 rs6545867 chr2:61651027 C/T cg15711740 chr2:61764176 XPO1 0.52 4.62 0.38 9.55e-6 Tuberculosis; TGCT cis rs941408 0.963 rs2537855 chr19:2806574 A/G cg06609049 chr19:2785107 THOP1 0.86 7.27 0.55 3.49e-11 Total cholesterol levels; TGCT cis rs11785400 0.928 rs10100287 chr8:143734836 C/T cg24634471 chr8:143751801 JRK 0.56 6.12 0.48 1.12e-8 Schizophrenia; TGCT cis rs60843830 1.000 rs9213 chr2:218386 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.69 6.11 0.48 1.17e-8 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9926296 0.605 rs8047486 chr16:89854025 A/T cg27121462 chr16:89883253 FANCA 0.81 8.95 0.63 4.42e-15 Vitiligo; TGCT cis rs6540559 0.543 rs672819 chr1:210436404 T/A cg22029157 chr1:209979665 IRF6 0.62 4.45 0.37 1.92e-5 Cleft lip with or without cleft palate; TGCT cis rs7267979 1.000 rs6138572 chr20:25435934 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6746896 0.959 rs2314398 chr2:97413488 C/G cg26085987 chr2:97230376 NA 0.19 4.63 0.38 9.18e-6 Bipolar disorder; TGCT cis rs35306767 0.903 rs34270014 chr10:904666 T/C cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs13082711 0.522 rs608374 chr3:27345397 G/A cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs1536827 0.541 rs11592587 chr10:135363653 G/A cg12448312 chr10:135032219 KNDC1 -0.53 -5.09 -0.42 1.27e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg03264133 chr6:25882463 NA -0.61 -5.68 -0.45 9.01e-8 Intelligence (multi-trait analysis); TGCT cis rs8013055 0.796 rs4074453 chr14:105998544 T/C cg19700328 chr14:106028568 NA -0.49 -5.2 -0.42 8.1e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs1635 0.655 rs73742541 chr6:28310615 T/C cg15743358 chr6:28303923 ZNF323 -1.29 -6.5 -0.5 1.73e-9 Schizophrenia; TGCT cis rs7267979 1.000 rs6083856 chr20:25407585 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4767364 1.000 rs2285810 chr12:112699540 T/C cg10833066 chr12:111807467 FAM109A 0.34 5.17 0.42 8.98e-7 Oral cavity and pharyngeal cancer; TGCT cis rs6693567 0.565 rs3754217 chr1:150480373 G/T cg09579323 chr1:150459698 TARS2 0.52 4.63 0.38 9.26e-6 Migraine; TGCT cis rs10540 1.000 rs79808876 chr11:465763 C/A cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs4820539 0.934 rs3788348 chr22:23467946 G/C cg14186256 chr22:23484241 RTDR1 0.98 11.82 0.73 4.6e-22 Bone mineral density; TGCT cis rs7698623 0.850 rs4147244 chr4:88779168 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs7216064 1.000 rs55896768 chr17:65913358 T/C cg12091567 chr17:66097778 LOC651250 -0.85 -6.33 -0.49 4.03e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs55882075 0.967 rs12656648 chr5:179152106 C/A cg14593053 chr5:179126677 CANX 0.47 5.04 0.41 1.57e-6 Monocyte percentage of white cells; TGCT cis rs9303401 0.614 rs28651036 chr17:57080471 G/A cg25039879 chr17:56429692 SUPT4H1 0.54 4.88 0.4 3.25e-6 Cognitive test performance; TGCT cis rs7017914 0.967 rs35115527 chr8:71643009 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs1472147 0.868 rs13227216 chr7:128490553 T/C cg00260937 chr7:128520193 KCP 0.42 5.96 0.47 2.38e-8 Calcium levels; TGCT cis rs60871478 0.636 rs4721600 chr7:871728 C/T cg15782153 chr7:917662 C7orf20 0.51 4.69 0.39 7.23e-6 Cerebrospinal P-tau181p levels; TGCT cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg21171335 chr12:122356390 WDR66 0.63 7.03 0.53 1.24e-10 Mean corpuscular volume; TGCT cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg10295955 chr4:187884368 NA -0.99 -15.24 -0.81 3.38e-30 Lobe attachment (rater-scored or self-reported); TGCT trans rs877282 0.945 rs11253397 chr10:789774 A/G cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs6964587 1.000 rs10281556 chr7:91660053 C/T cg17063962 chr7:91808500 NA -0.91 -10.53 -0.69 6.54e-19 Breast cancer; TGCT cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg17054783 chr10:134559939 INPP5A 0.24 4.61 0.38 9.88e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs617219 0.710 rs10054122 chr5:78581371 A/T cg23514016 chr5:78407564 BHMT -0.33 -5.04 -0.41 1.6e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6430585 0.583 rs12475516 chr2:136560761 C/G cg07169764 chr2:136633963 MCM6 1.05 10.03 0.67 1.09e-17 Corneal structure; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg02073558 chr3:44770973 ZNF501 0.69 6.87 0.52 2.8e-10 Depressive symptoms; TGCT cis rs13191362 0.507 rs1954810 chr6:163061749 C/T cg06582575 chr6:163149167 PACRG;PARK2 -0.6 -5.74 -0.46 6.71e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs116095464 0.558 rs10079760 chr5:230778 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs1008375 1.000 rs28545485 chr4:17645376 C/T cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7178572 0.524 rs12904088 chr15:77399397 C/G cg22256960 chr15:77711686 NA -0.85 -8.71 -0.62 1.61e-14 Type 2 diabetes; TGCT cis rs4808199 0.842 rs11085259 chr19:19445856 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.63 4.56 0.38 1.23e-5 Nonalcoholic fatty liver disease; TGCT cis rs9527 0.590 rs11191547 chr10:104843148 C/T cg15744005 chr10:104629667 AS3MT -0.43 -4.92 -0.4 2.69e-6 Arsenic metabolism; TGCT cis rs593531 0.571 rs35170680 chr11:74085420 T/G cg25592907 chr11:73676012 DNAJB13 0.33 4.81 0.4 4.23e-6 Neuroticism; TGCT cis rs9611565 0.592 rs4822040 chr22:41963553 C/G cg03806693 chr22:41940476 POLR3H -1.01 -10.42 -0.68 1.19e-18 Vitiligo; TGCT cis rs2295359 0.892 rs72676069 chr1:67658954 T/C cg12940439 chr1:67600707 NA 0.6 6.2 0.49 7.79e-9 Psoriasis; TGCT cis rs597480 0.510 rs11607789 chr11:85526151 C/T cg11817631 chr11:85522609 SYTL2 0.52 4.87 0.4 3.31e-6 Drug-induced liver injury (nonsteroidal anti-inflammatory drugs); TGCT cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs929354 0.739 rs12533082 chr7:157014172 T/A cg05182265 chr7:156933206 UBE3C -0.4 -9.08 -0.63 2.11e-15 Body mass index; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg06873352 chr17:61820015 STRADA 0.57 6.22 0.49 6.85e-9 Prudent dietary pattern; TGCT cis rs909674 0.818 rs8137426 chr22:39844350 T/G cg11247378 chr22:39784982 NA -0.72 -8.56 -0.61 3.55e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg26531700 chr6:26746687 NA 0.66 6.56 0.51 1.32e-9 Intelligence (multi-trait analysis); TGCT cis rs17030434 0.654 rs28640133 chr4:154645926 T/A cg14289246 chr4:154710475 SFRP2 -0.76 -5.72 -0.46 7.51e-8 Electrocardiographic conduction measures; TGCT cis rs9527 0.637 rs11191424 chr10:104625886 G/A cg04362960 chr10:104952993 NT5C2 0.57 4.9 0.4 2.89e-6 Arsenic metabolism; TGCT cis rs7635838 0.722 rs6773963 chr3:11511975 G/A cg00170343 chr3:11313890 ATG7 0.69 6.64 0.51 8.86e-10 HDL cholesterol; TGCT cis rs2404602 0.716 rs67204011 chr15:76846555 C/T cg22467129 chr15:76604101 ETFA -0.47 -5.4 -0.44 3.21e-7 Blood metabolite levels; TGCT cis rs853679 0.517 rs9380065 chr6:28144751 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs1692580 0.807 rs60635488 chr1:2202572 C/T cg21194808 chr1:2205498 SKI 0.29 5.52 0.44 1.88e-7 Coronary artery disease; TGCT cis rs9467773 1.000 rs2224380 chr6:26553943 G/A cg05738196 chr6:26577821 NA 0.91 13.14 0.76 2.99e-25 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg03517284 chr6:25882590 NA -0.77 -8.05 -0.59 5.9e-13 Blood metabolite levels; TGCT cis rs9303401 0.580 rs2013166 chr17:56637630 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs6430585 0.527 rs60966546 chr2:136401843 C/T cg07169764 chr2:136633963 MCM6 0.98 8.44 0.6 7.04e-14 Corneal structure; TGCT cis rs9972944 0.729 rs7211481 chr17:63766434 A/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.16 -0.42 9.6e-7 Total body bone mineral density; TGCT cis rs7845219 0.544 rs9643351 chr8:95917290 C/T cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs7439150 0.954 rs2059503 chr4:155493419 A/T cg22130008 chr4:155548532 NA -0.49 -6.41 -0.5 2.74e-9 Fibrinogen levels; TGCT cis rs7819412 0.560 rs13265553 chr8:10989057 G/A cg21775007 chr8:11205619 TDH -0.6 -5.3 -0.43 5.03e-7 Triglycerides; TGCT cis rs782590 1.000 rs782590 chr2:55843413 C/T cg03859395 chr2:55845619 SMEK2 0.93 11.31 0.71 8.26e-21 Metabolic syndrome; TGCT cis rs17221829 0.549 rs1844196 chr11:89389256 A/G cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs425277 1.000 rs262654 chr1:2089526 G/A cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs4072705 0.967 rs4838195 chr9:127351217 G/A cg13476313 chr9:127244764 NR5A1 0.28 4.5 0.37 1.54e-5 Menarche (age at onset); TGCT cis rs35306767 0.903 rs765867 chr10:869901 G/T cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs344364 0.511 rs911392 chr16:1947259 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg12311346 chr5:56204834 C5orf35 -0.66 -6.63 -0.51 9.22e-10 Initial pursuit acceleration; TGCT cis rs514406 0.547 rs377808 chr1:53190359 T/G cg16325326 chr1:53192061 ZYG11B 0.89 13.01 0.76 6.31e-25 Monocyte count; TGCT cis rs7698623 0.850 rs1982623 chr4:88790777 C/G cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg17264618 chr3:40429014 ENTPD3 0.33 4.72 0.39 6.27e-6 Renal cell carcinoma; TGCT cis rs9788682 0.747 rs938682 chr15:78896547 A/G cg24631222 chr15:78858424 CHRNA5 0.89 7.01 0.53 1.35e-10 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs35883536 0.626 rs7536054 chr1:101047849 A/G cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs13108904 0.539 rs13141992 chr4:1340765 C/T cg13395646 chr4:1353034 KIAA1530 -0.6 -8.06 -0.59 5.55e-13 Obesity-related traits; TGCT cis rs36051895 0.632 rs7022901 chr9:5177680 C/G cg02405213 chr9:5042618 JAK2 -0.74 -10.54 -0.69 6.17e-19 Pediatric autoimmune diseases; TGCT cis rs7582180 0.715 rs920270 chr2:100917961 T/C cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.89e-7 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs61580655 chr5:597564 A/G cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs6670062 0.536 rs1778538 chr1:247412899 G/A cg01868367 chr1:247372405 NA 0.27 4.57 0.38 1.15e-5 Trans fatty acid levels; TGCT cis rs3796352 1.000 rs17052727 chr3:53070914 T/C cg27565382 chr3:53032988 SFMBT1 0.42 4.56 0.38 1.21e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1008375 1.000 rs10805357 chr4:17652352 G/A cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs644799 0.930 rs587123 chr11:95560539 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg20999797 chr1:1681921 NA 0.19 4.87 0.4 3.28e-6 Body mass index; TGCT cis rs4720575 1.000 rs1859522 chr7:47096901 G/A cg00036614 chr7:47093842 NA -0.21 -5.35 -0.43 4.1e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs7552404 0.961 rs1061337 chr1:76227022 A/G cg03433033 chr1:76189801 ACADM 0.83 9.53 0.65 1.69e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7582180 0.585 rs13031711 chr2:100939433 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs4319547 0.695 rs4758645 chr12:122946487 G/A cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.33 -0.43 4.48e-7 Body mass index; TGCT cis rs11105298 0.891 rs10858864 chr12:89846230 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2439831 0.850 rs28578398 chr15:44075046 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs77633900 0.614 rs280012 chr15:76974854 G/T cg21673338 chr15:77095150 SCAPER -0.5 -4.92 -0.4 2.68e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs3741404 0.672 rs4980524 chr11:63959259 A/C cg00022866 chr11:64108440 CCDC88B 0.24 4.55 0.38 1.25e-5 Platelet count; TGCT cis rs7582180 0.629 rs4850926 chr2:100954117 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.559 rs6920256 chr6:26537801 G/A cg16898833 chr6:26189333 HIST1H4D 1.02 5.22 0.42 7.42e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs7824557 0.689 rs10481454 chr8:11109303 C/G cg15556689 chr8:8085844 FLJ10661 -0.8 -6.72 -0.52 5.94e-10 Retinal vascular caliber; TGCT cis rs597539 0.617 rs672853 chr11:68636362 G/A cg21862992 chr11:68658383 NA 0.46 6.37 0.5 3.37e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9527 0.518 rs12771834 chr10:104655419 G/A cg15744005 chr10:104629667 AS3MT -0.61 -4.96 -0.41 2.3e-6 Arsenic metabolism; TGCT trans rs608114 1.000 rs608114 chr6:96376698 A/T cg04008557 chr11:2826328 KCNQ1 -0.65 -6.82 -0.52 3.51e-10 Response to abacavir-containing treatment in HIV-1 infection (virologic failure);Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg05665937 chr4:1216051 CTBP1 0.22 4.47 0.37 1.75e-5 Obesity-related traits; TGCT trans rs13064411 0.542 rs1463643 chr3:113215447 A/G cg00307254 chr3:126706825 PLXNA1 0.34 6.72 0.52 5.79e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs116161686 0.500 rs55871867 chr1:210051029 A/G cg22029157 chr1:209979665 IRF6 0.74 5.6 0.45 1.31e-7 Coronary artery disease; TGCT cis rs4665809 1.000 rs12469163 chr2:26283587 T/C cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs7264396 0.790 rs6121018 chr20:34249060 C/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs4072705 0.933 rs10760376 chr9:127554070 A/G cg13476313 chr9:127244764 NR5A1 -0.29 -4.62 -0.38 9.39e-6 Menarche (age at onset); TGCT cis rs11711311 1.000 rs12632983 chr3:113481913 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs11098499 0.954 rs6848389 chr4:120402622 A/G cg09307838 chr4:120376055 NA 0.73 6.95 0.53 1.84e-10 Corneal astigmatism; TGCT cis rs9399135 0.935 rs987690 chr6:135350379 A/G cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs10858047 0.883 rs12040800 chr1:115108577 T/C cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs6598955 0.724 rs884533 chr1:26585657 G/T cg04990556 chr1:26633338 UBXN11 -0.91 -11.45 -0.72 3.65e-21 Obesity-related traits; TGCT cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg11062466 chr8:58055876 NA 0.44 4.68 0.39 7.38e-6 Developmental language disorder (linguistic errors); TGCT cis rs9443645 0.869 rs6926537 chr6:79554193 T/A cg09184832 chr6:79620586 NA -0.48 -5.35 -0.43 4.01e-7 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs11130315 chr3:52697163 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg11502198 chr6:26597334 ABT1 0.53 4.9 0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT cis rs877282 1.000 rs12775643 chr10:773242 G/A cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs11792861 0.781 rs838835 chr9:111758590 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.51 -4.83 -0.4 3.89e-6 Menarche (age at onset); TGCT cis rs11190604 0.767 rs10883490 chr10:102194775 C/T cg16005271 chr10:102321736 NA 0.47 4.66 0.39 8.14e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4689388 0.926 rs4308429 chr4:6294001 A/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1903068 0.719 rs1350545 chr4:56004454 C/T cg01777861 chr4:56023843 NA 0.51 5.61 0.45 1.26e-7 Endometriosis; TGCT cis rs1008375 1.000 rs10027755 chr4:17615954 G/C cg10189774 chr4:17578691 LAP3 0.54 4.78 0.39 4.9100000000000004e-06 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs78456975 0.527 rs7590742 chr2:1575049 A/T cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs853679 0.546 rs493161 chr6:27850714 A/T cg08798685 chr6:27730294 NA -0.36 -5.06 -0.41 1.45e-6 Depression; TGCT cis rs4689388 0.890 rs6446481 chr4:6295583 C/A cg14416269 chr4:6271139 WFS1 0.39 4.99 0.41 2.01e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3749237 0.595 rs1568661 chr3:49520958 A/G cg02487422 chr3:49467188 NICN1 0.58 5.89 0.47 3.43e-8 Resting heart rate; TGCT cis rs2361718 0.521 rs2361724 chr17:78099114 G/A cg09238746 chr17:78121135 EIF4A3 -1.07 -9.91 -0.66 2.06e-17 Yeast infection; TGCT cis rs3091242 0.933 rs3093584 chr1:25668714 T/C cg10117171 chr1:25599238 RHD 0.35 5.67 0.45 9.51e-8 Erythrocyte sedimentation rate; TGCT cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs9399401 0.667 rs1329707 chr6:142724439 T/C cg03128060 chr6:142623767 GPR126 0.37 4.47 0.37 1.77e-5 Chronic obstructive pulmonary disease; TGCT cis rs2404602 0.692 rs55864032 chr15:77122548 A/G cg22467129 chr15:76604101 ETFA -0.45 -5.04 -0.41 1.63e-6 Blood metabolite levels; TGCT cis rs148734725 1 rs148734725 chr3:49406708 G/A cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Educational attainment (college completion); TGCT cis rs1023500 0.573 rs133381 chr22:42470608 C/G cg05082376 chr22:42548792 NA -0.23 -5.38 -0.43 3.61e-7 Schizophrenia; TGCT cis rs6088590 1.000 rs11698977 chr20:33449691 C/T cg06115741 chr20:33292138 TP53INP2 0.66 5.26 0.43 5.99e-7 Coronary artery disease; TGCT cis rs7246657 0.606 rs2972439 chr19:38212581 T/C cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs644799 1.000 rs3748256 chr11:95521953 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 11.08 0.71 2.9e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11711311 0.712 rs2271498 chr3:113334752 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.6 -5.1 -0.42 1.24e-6 IgG glycosylation; TGCT cis rs9911578 1.000 rs999431 chr17:56854441 A/G cg12560992 chr17:57184187 TRIM37 0.77 9.32 0.64 5.7e-16 Intelligence (multi-trait analysis); TGCT cis rs77633900 0.614 rs2469242 chr15:76876710 A/G cg21673338 chr15:77095150 SCAPER -0.51 -4.7 -0.39 6.69e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs1499614 0.522 rs13247442 chr7:66188858 T/C cg18252515 chr7:66147081 NA -1.11 -5.89 -0.47 3.32e-8 Gout; TGCT cis rs346785 0.692 rs3803737 chr17:74289500 G/A cg09812376 chr17:74270190 QRICH2 -0.36 -5.33 -0.43 4.43e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg14159672 chr1:205819179 PM20D1 0.62 7.71 0.57 3.56e-12 Menarche (age at onset); TGCT cis rs17826219 0.706 rs9905827 chr17:29192168 C/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.6 -0.38 1.03e-5 Body mass index; TGCT cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg24250549 chr1:154909240 PMVK -0.6 -6.27 -0.49 5.39e-9 Prostate cancer; TGCT cis rs955333 0.543 rs6557365 chr6:154924457 A/G cg22719623 chr6:154360732 OPRM1 0.35 4.67 0.39 7.75e-6 Diabetic kidney disease; TGCT cis rs6088590 0.523 rs6058084 chr20:33183804 C/T cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs941408 1.000 rs1640266 chr19:2787832 T/G cg06609049 chr19:2785107 THOP1 0.81 7.81 0.57 2.05e-12 Total cholesterol levels; TGCT cis rs7119038 0.509 rs10892256 chr11:118578705 G/A cg19308663 chr11:118741387 NA 0.24 4.5 0.37 1.54e-5 Sjögren's syndrome; TGCT cis rs10782582 0.609 rs5745331 chr1:76273313 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs2289681 0.525 rs2277617 chr17:42977073 T/G cg15193461 chr17:42977049 CCDC103;EFTUD2 -0.7 -6.23 -0.49 6.57e-9 Cognitive function; TGCT cis rs7614311 0.636 rs3821902 chr3:63941697 T/G cg22134162 chr3:63841271 THOC7 -0.46 -5.83 -0.46 4.5e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs17102423 0.929 rs4902363 chr14:65601689 T/G cg11161011 chr14:65562177 MAX -0.47 -6.26 -0.49 5.62e-9 Obesity-related traits; TGCT cis rs7959452 0.503 rs7300266 chr12:69654187 A/G cg20891283 chr12:69753455 YEATS4 0.63 6.09 0.48 1.32e-8 Blood protein levels; TGCT cis rs10838634 1.000 rs7118097 chr11:46820899 A/G cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs6831352 1.000 rs6837685 chr4:100049145 G/A cg12011299 chr4:100065546 ADH4 0.41 5.2 0.42 8.11e-7 Alcohol dependence; TGCT cis rs10927875 0.557 rs1572381 chr1:16344494 G/A cg22431228 chr1:16359049 CLCNKA -0.29 -5.94 -0.47 2.68e-8 Dilated cardiomyopathy; TGCT cis rs12134133 1.000 rs1429904 chr1:207461884 A/C cg02152968 chr1:207494213 CD55 0.57 4.47 0.37 1.74e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs11785400 0.793 rs9774627 chr8:143731267 G/A cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.79e-7 Schizophrenia; TGCT trans rs4919669 0.668 rs7094614 chr10:104334874 G/C cg24066601 chr6:26271455 HIST1H3G 0.66 6.81 0.52 3.7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs9467773 1.000 rs9467783 chr6:26542894 C/T cg26531700 chr6:26746687 NA 0.46 4.54 0.38 1.33e-5 Intelligence (multi-trait analysis); TGCT cis rs806215 0.526 rs3808088 chr7:127526038 C/T cg11539674 chr7:127291444 SND1 -0.36 -4.53 -0.38 1.39e-5 Type 2 diabetes; TGCT cis rs9486719 1.000 rs10457159 chr6:96993139 G/A cg06623918 chr6:96969491 KIAA0776 -0.99 -7.99 -0.58 7.78e-13 Migraine;Coronary artery disease; TGCT cis rs7226408 0.842 rs1609425 chr18:34345684 A/G cg06757138 chr18:34340585 FHOD3 -0.3 -5.12 -0.42 1.16e-6 Obesity-related traits; TGCT cis rs424971 0.933 rs8047999 chr16:85947527 G/C cg04599946 chr16:85936480 IRF8 0.25 4.48 0.37 1.64e-5 Monocyte count; TGCT cis rs12136530 0.593 rs2314145 chr1:19736843 C/G cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs904251 0.861 rs2776877 chr6:37487135 G/A cg25019722 chr6:37503610 NA -0.51 -7.03 -0.53 1.24e-10 Cognitive performance; TGCT cis rs12136530 0.577 rs12066114 chr1:19792527 A/G cg00755546 chr1:19971792 NBL1 0.37 4.64 0.38 8.74e-6 Lead levels in blood; TGCT cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs2406342 0.511 rs472676 chr18:74607924 C/T cg16472389 chr18:74514291 NA 0.46 4.63 0.38 9.19e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin); TGCT cis rs17384381 0.734 rs12129013 chr1:85891709 A/C cg16011679 chr1:85725395 C1orf52 0.7 6.32 0.49 4.33e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.764 rs9403726 chr6:145901686 G/T cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12142240 0.698 rs932816 chr1:46859749 G/A cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs2445762 0.642 rs72729210 chr15:51633629 G/A cg00184732 chr15:51633821 GLDN 0.53 5.37 0.43 3.72e-7 Hormone measurements; TGCT cis rs2063714 0.658 rs12196864 chr6:157212862 C/T cg23222435 chr6:157204239 ARID1B -0.31 -5.12 -0.42 1.11e-6 Sitting height ratio; TGCT cis rs7246657 0.722 rs3101746 chr19:38146400 T/A cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs2188554 0.740 rs213933 chr7:117211054 A/G cg09181792 chr7:117119393 CFTR 0.52 4.68 0.39 7.3e-6 Esophageal adenocarcinoma; TGCT cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs12541335 0.579 rs59283125 chr8:22212311 G/A cg26039829 chr8:22132926 PIWIL2 0.28 5.23 0.42 7.05e-7 Hypertriglyceridemia; TGCT cis rs1729951 0.546 rs12054218 chr3:136677496 C/G cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs1801251 1.000 rs13013142 chr2:233600606 A/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs2486012 1.000 rs3011221 chr1:44312109 A/G cg12908607 chr1:44402522 ARTN -0.69 -5.57 -0.45 1.49e-7 Intelligence (multi-trait analysis); TGCT trans rs2727020 0.930 rs1164686 chr11:49291822 C/T cg15704280 chr7:45808275 SEPT13 0.72 7.71 0.57 3.47e-12 Coronary artery disease; TGCT cis rs35883536 0.513 rs4907910 chr1:101013277 T/A cg10298815 chr1:101004474 GPR88 0.24 4.6 0.38 1.01e-5 Monocyte count; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg00024416 chr22:24240387 NA -0.25 -4.76 -0.39 5.27e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7267979 1.000 rs2257985 chr20:25269743 G/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4819052 1.000 rs28628220 chr21:46663741 G/C cg06618935 chr21:46677482 NA -0.37 -5.04 -0.41 1.64e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10465746 0.935 rs11580836 chr1:84333310 C/T cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs7954584 0.567 rs11043233 chr12:122330733 C/T cg13699009 chr12:122356056 WDR66 0.27 5.34 0.43 4.24e-7 Mean corpuscular volume; TGCT cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg00149659 chr3:10157352 C3orf10 1.05 5.81 0.46 4.95e-8 Alzheimer's disease; TGCT cis rs1018836 0.828 rs4734250 chr8:91591239 C/G cg16814680 chr8:91681699 NA 0.68 6.72 0.52 5.82e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg06035815 chr6:26189597 HIST1H4D -0.44 -4.58 -0.38 1.12e-5 Schizophrenia; TGCT cis rs1865760 0.865 rs1436306 chr6:25948421 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT trans rs6089829 0.855 rs6062781 chr20:61667128 G/A cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs3741151 1.000 rs112840535 chr11:73066771 G/A cg17517138 chr11:73019481 ARHGEF17 0.91 4.63 0.38 9e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs4819052 0.851 rs4819042 chr21:46660072 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs10802346 0.545 rs10924568 chr1:246385482 C/A cg13514129 chr1:39547527 MACF1 0.96 8.52 0.61 4.45e-14 Fractional exhaled nitric oxide (childhood); TGCT cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.76 5.5 0.44 2.07e-7 Platelet count; TGCT cis rs4851266 0.898 rs2309812 chr2:100869702 C/T cg22139774 chr2:100720529 AFF3 -0.32 -4.66 -0.39 7.89e-6 Educational attainment; TGCT cis rs2880765 0.566 rs17553790 chr15:86013665 C/T cg13263323 chr15:86062960 AKAP13 0.22 5.04 0.41 1.64e-6 Coronary artery disease; TGCT cis rs7666738 0.716 rs6827474 chr4:99089683 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.51 0.44 2.02e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs3125734 0.633 rs6479791 chr10:63980341 T/C cg09941381 chr10:64027924 RTKN2 -0.36 -5.53 -0.44 1.83e-7 Rheumatoid arthritis; TGCT cis rs853679 0.527 rs853683 chr6:28295039 A/G cg18815343 chr6:28367644 ZSCAN12 -0.46 -4.81 -0.4 4.24e-6 Depression; TGCT cis rs1005277 0.579 rs2472183 chr10:38392495 T/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1005277 0.522 rs289650 chr10:37975505 G/T cg25427524 chr10:38739819 LOC399744 -0.33 -6.54 -0.51 1.47e-9 Extrinsic epigenetic age acceleration; TGCT cis rs12950390 0.548 rs7215477 chr17:45858117 A/C cg06532163 chr17:45867833 NA 0.26 4.7 0.39 6.7e-6 IgG glycosylation; TGCT cis rs2730245 0.569 rs842692 chr7:158657228 T/C cg24397884 chr7:158709396 WDR60 0.38 4.88 0.4 3.13e-6 Height; TGCT cis rs7394190 0.748 rs4082339 chr10:75539812 C/T cg07699608 chr10:75541558 CHCHD1 -0.73 -5.16 -0.42 9.35e-7 Incident atrial fibrillation; TGCT cis rs3733585 0.806 rs11723382 chr4:9954660 T/C cg00071950 chr4:10020882 SLC2A9 -0.63 -8.02 -0.58 6.93e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1534166 0.602 rs3817524 chr3:133526403 C/T cg08048268 chr3:133502702 NA 0.39 4.63 0.38 9e-6 Alcohol consumption (transferrin glycosylation); TGCT cis rs2404602 0.583 rs11072580 chr15:76540231 G/A cg26408565 chr15:76604113 ETFA -0.48 -6.75 -0.52 4.94e-10 Blood metabolite levels; TGCT cis rs7590720 0.759 rs6737781 chr2:216914920 A/G cg12620499 chr2:216877984 MREG 0.79 7.33 0.55 2.61e-11 Alcohol dependence; TGCT cis rs3812831 0.654 rs6560933 chr13:114937294 A/G cg06611532 chr13:114900021 NA -0.29 -5.45 -0.44 2.6e-7 Schizophrenia; TGCT cis rs610932 0.517 rs650943 chr11:60006765 G/T cg18570331 chr11:60101691 MS4A6E -0.65 -5.34 -0.43 4.31e-7 Alzheimer's disease; TGCT cis rs67073037 0.592 rs4558548 chr2:28985674 C/G cg09522027 chr2:28974177 PPP1CB -0.56 -4.67 -0.39 7.57e-6 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs6089829 0.855 rs6062781 chr20:61667128 G/A cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7213347 0.780 rs216224 chr17:2156285 T/C cg13315690 chr17:1944831 OVCA2;DPH1 0.4 5.11 0.42 1.2e-6 Total body bone mineral density; TGCT cis rs1008375 0.931 rs1860592 chr4:17577028 C/G cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1048238 0.506 rs7547314 chr1:16186722 G/A cg21385522 chr1:16154831 NA 0.61 7.01 0.53 1.34e-10 Systolic blood pressure; TGCT cis rs62103177 0.810 rs62103189 chr18:77627815 G/A cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT trans rs916888 0.821 rs415430 chr17:44859144 C/T cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2832077 0.527 rs59730679 chr21:30226244 T/C cg24692254 chr21:30365293 RNF160 -0.59 -5.05 -0.41 1.53e-6 Cognitive test performance; TGCT cis rs6448317 0.863 rs2695228 chr4:24901985 C/T cg21108841 chr4:24914750 CCDC149 0.68 5.63 0.45 1.13e-7 Heschl's gyrus morphology; TGCT cis rs9611565 0.649 rs139559 chr22:42191636 A/G cg03806693 chr22:41940476 POLR3H -0.88 -8.52 -0.61 4.43e-14 Vitiligo; TGCT cis rs6490294 0.904 rs112426410 chr12:112407438 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs3784262 0.740 rs8032572 chr15:58311280 A/G cg12031962 chr15:58353849 ALDH1A2 0.45 6.69 0.51 6.94e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs66573146 0.808 rs55942328 chr4:6990960 T/G cg00086871 chr4:6988644 TBC1D14 0.95 4.69 0.39 7.15e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7666738 0.830 rs28516388 chr4:98987449 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9399135 0.967 rs4376365 chr6:135307740 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.75 0.39 5.5e-6 Red blood cell count; TGCT cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg13395646 chr4:1353034 KIAA1530 -0.38 -4.72 -0.39 6.28e-6 Obesity-related traits; TGCT cis rs1801251 1.000 rs778166 chr2:233664097 A/T cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.28e-9 Coronary artery disease; TGCT cis rs3008870 1.000 rs1925408 chr1:67365034 C/T cg11518657 chr1:67396239 MIER1 0.53 4.72 0.39 6.16e-6 Lymphocyte percentage of white cells; TGCT cis rs2242116 0.796 rs4587 chr3:46963502 T/C cg27129171 chr3:47204927 SETD2 0.66 6.34 0.49 3.88e-9 Birth weight; TGCT cis rs11955175 1.000 rs111310950 chr5:40641951 G/T cg17351974 chr5:40835760 RPL37 0.76 4.75 0.39 5.46e-6 Bipolar disorder and schizophrenia; TGCT cis rs9291683 0.597 rs11722989 chr4:10126139 A/G cg11266682 chr4:10021025 SLC2A9 -0.46 -5.5 -0.44 2.12e-7 Bone mineral density; TGCT cis rs4862750 0.914 rs11945845 chr4:187874136 T/C cg03452623 chr4:187889614 NA -0.38 -5.67 -0.45 9.41e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs3733585 0.673 rs7376505 chr4:9952744 C/A cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs9951602 1.000 rs1903723 chr18:76646571 A/G cg02800362 chr5:177631904 HNRNPAB 0.98 7.2 0.54 5.03e-11 Obesity-related traits; TGCT cis rs7917772 0.536 rs11191361 chr10:104411958 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 7.97 0.58 8.86e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10851411 0.908 rs10454039 chr15:42832534 C/T cg23803468 chr15:43513504 EPB42 -0.23 -4.44 -0.37 1.93e-5 Glucose homeostasis traits; TGCT cis rs2729354 0.909 rs2729374 chr11:57326927 C/T cg24343310 chr11:57249947 NA 0.29 4.92 0.4 2.73e-6 Blood protein levels; TGCT cis rs801193 0.967 rs2707849 chr7:66152712 T/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs13326165 0.760 rs11711934 chr3:52358117 T/C cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7.1e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1865760 1.000 rs7757666 chr6:25902626 T/C cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs6977660 0.652 rs10486362 chr7:19755224 A/G cg05791153 chr7:19748676 TWISTNB -1.21 -7.93 -0.58 1.07e-12 Thyroid stimulating hormone; TGCT cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs12530845 1.000 rs12530845 chr7:135329978 T/C cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs9894429 0.546 rs55917554 chr17:79608776 T/C cg18240062 chr17:79603768 NPLOC4 0.75 7.11 0.54 8.06e-11 Eye color traits; TGCT cis rs9894429 0.789 rs7213849 chr17:79567610 C/T cg21984481 chr17:79567631 NPLOC4 0.26 4.9 0.4 2.91e-6 Eye color traits; TGCT cis rs826838 0.874 rs11183816 chr12:38834656 T/G cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs11785400 1.000 rs6988393 chr8:143740596 A/G cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs12478296 1.000 rs12469535 chr2:243044147 G/A cg06360820 chr2:242988706 NA -0.59 -4.52 -0.38 1.45e-5 Obesity-related traits; TGCT cis rs28595532 0.764 rs55704595 chr4:119780607 G/A cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs9807989 0.773 rs72823661 chr2:102968716 G/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs7818382 0.967 rs7812465 chr8:96050557 C/T cg13393036 chr8:95962371 TP53INP1 0.48 5.95 0.47 2.55e-8 Alzheimer's disease (late onset); TGCT cis rs6484504 0.576 rs11031320 chr11:31242545 C/T cg14844989 chr11:31128820 NA -0.23 -4.51 -0.38 1.47e-5 Red blood cell count; TGCT cis rs910187 0.537 rs2154035 chr20:45760083 T/G cg27589058 chr20:45804311 EYA2 -0.35 -6.72 -0.52 5.88e-10 Migraine; TGCT cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs4776059 1.000 rs2288271 chr15:52886466 A/G cg25063058 chr15:52860530 ARPP19 0.53 4.79 0.4 4.59e-6 Schizophrenia; TGCT cis rs6087990 0.735 rs6087420 chr20:31359391 G/A cg13636640 chr20:31349939 DNMT3B 0.97 12.92 0.76 1e-24 Ulcerative colitis; TGCT cis rs700651 0.789 rs1147169 chr2:198901395 C/T cg00792783 chr2:198669748 PLCL1 -0.57 -4.99 -0.41 2.03e-6 Intracranial aneurysm; TGCT cis rs939574 0.929 rs10190834 chr2:220070301 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.06 -6.52 -0.51 1.6e-9 Platelet distribution width; TGCT cis rs2486012 0.737 rs2906470 chr1:44306559 T/C cg12908607 chr1:44402522 ARTN -0.72 -5.68 -0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg00149659 chr3:10157352 C3orf10 0.77 5.14 0.42 1.03e-6 Alzheimer's disease; TGCT cis rs7666738 0.830 rs13121766 chr4:98935766 A/C cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.8e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.966 rs6050567 chr20:25354561 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs910187 0.678 rs3818012 chr20:45816594 G/A cg27589058 chr20:45804311 EYA2 -0.35 -7.58 -0.56 7.14e-12 Migraine; TGCT cis rs2153535 0.580 rs1335636 chr6:8465047 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4242434 0.757 rs4872531 chr8:22529695 A/G cg21658235 chr8:22456391 C8orf58 -0.46 -5.04 -0.41 1.6e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT trans rs1814175 0.817 rs7946556 chr11:49944874 G/A cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs708547 0.874 rs7674167 chr4:57721477 A/G cg25525207 chr4:57843836 C4orf14;POLR2B 0.5 4.47 0.37 1.71e-5 Response to bleomycin (chromatid breaks); TGCT cis rs6669919 0.901 rs7527396 chr1:211667857 C/T cg26515805 chr1:211431828 RCOR3 -0.4 -4.69 -0.39 7.22e-6 Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs34295495 chr7:116068266 C/A cg16553024 chr7:116138462 CAV2 -0.48 -5.31 -0.43 4.89e-7 P wave duration; TGCT cis rs9916302 0.904 rs9898773 chr17:37532507 C/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs2410601 0.503 rs7843667 chr8:18925228 G/A cg19414122 chr8:18896631 NA -0.28 -4.64 -0.38 8.68e-6 Urinary albumin excretion rate in type 1 diabetes; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg11905131 chr22:24372483 LOC391322 -0.71 -7.19 -0.54 5.46e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12579753 0.879 rs1986537 chr12:82156475 G/C cg21231944 chr12:82153410 PPFIA2 -0.34 -4.52 -0.38 1.4e-5 Resting heart rate; TGCT cis rs72781680 0.898 rs72798049 chr2:23958002 C/G cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs4824093 0.610 rs7410534 chr22:50289925 C/T cg14114931 chr22:50943910 LMF2 0.37 4.53 0.38 1.35e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg06238570 chr21:40685208 BRWD1 -0.85 -8.62 -0.61 2.68e-14 Cognitive function; TGCT cis rs9796 0.870 rs7181816 chr15:41358720 T/A cg18705301 chr15:41695430 NDUFAF1 -0.43 -5.62 -0.45 1.22e-7 Menopause (age at onset); TGCT cis rs6424115 0.830 rs2503002 chr1:24196957 C/G cg15997130 chr1:24165203 NA 0.87 10.12 0.67 6.32e-18 Immature fraction of reticulocytes; TGCT cis rs57602752 1.000 rs1961317 chr10:120654022 A/G cg18286127 chr10:120070743 C10orf84 0.55 4.48 0.37 1.69e-5 Cannabis dependence; TGCT cis rs13256369 0.802 rs12681925 chr8:8561649 G/A cg17143192 chr8:8559678 CLDN23 0.54 5.03 0.41 1.64e-6 Obesity-related traits; TGCT cis rs4720575 1.000 rs4720574 chr7:47085597 A/C cg00036614 chr7:47093842 NA -0.2 -4.99 -0.41 1.95e-6 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs7781977 0.669 rs7791218 chr7:50353627 G/A cg14216940 chr7:50343131 IKZF1 0.36 4.55 0.38 1.26e-5 IgG glycosylation; TGCT cis rs7772486 0.686 rs857882 chr6:145969716 T/G cg23711669 chr6:146136114 FBXO30 -0.86 -9.6 -0.65 1.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs939574 0.722 rs115402093 chr2:220096128 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.0 4.56 0.38 1.2e-5 Platelet distribution width; TGCT cis rs514406 0.505 rs146750 chr1:53183447 C/G cg16325326 chr1:53192061 ZYG11B 0.84 12.01 0.73 1.59e-22 Monocyte count; TGCT cis rs2073300 1.000 rs6106655 chr20:23441982 C/G cg09953122 chr20:23471693 CST8 -0.61 -4.45 -0.37 1.9e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7552404 0.924 rs1146574 chr1:76202671 A/G cg22875332 chr1:76189707 ACADM 0.72 8.9 0.62 5.76e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg00684032 chr4:1343700 KIAA1530 -0.23 -4.98 -0.41 2.08e-6 Obesity-related traits; TGCT cis rs743757 1.000 rs734767 chr3:50431410 C/G cg07344955 chr3:50374863 RASSF1 0.79 5.24 0.43 6.66e-7 Diastolic blood pressure; TGCT cis rs3751972 0.748 rs4796172 chr17:26198381 C/T cg02948944 chr17:26242737 NA -0.45 -6.38 -0.5 3.26e-9 Fractional exhaled nitric oxide (childhood); TGCT cis rs727505 0.954 rs17327014 chr7:124709349 C/T cg23710748 chr7:124431027 NA -0.27 -4.7 -0.39 6.77e-6 Lewy body disease; TGCT cis rs40363 1.000 rs37769 chr16:3514580 C/G cg00484396 chr16:3507460 NAT15 0.44 5.08 0.41 1.36e-6 Tuberculosis; TGCT cis rs6430585 0.528 rs75524146 chr2:136725459 C/T cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs6754311 0.773 rs309130 chr2:136631031 C/A cg07169764 chr2:136633963 MCM6 -0.65 -6.06 -0.48 1.5e-8 Mosquito bite size; TGCT cis rs6545883 0.929 rs3821222 chr2:61713526 C/G cg15711740 chr2:61764176 XPO1 -0.56 -5.3 -0.43 5.03e-7 Tuberculosis; TGCT cis rs9486719 0.948 rs2472906 chr6:96875318 G/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs3806843 0.966 rs2563255 chr5:140142547 T/C cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2204008 0.837 rs12369089 chr12:38060263 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs5769765 0.874 rs4624 chr22:50281917 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.81 0.73 5.03e-22 Schizophrenia; TGCT cis rs546131 0.642 rs836950 chr11:34852020 C/G cg06937548 chr11:34938143 PDHX;APIP -0.52 -4.56 -0.38 1.21e-5 Lung disease severity in cystic fibrosis; TGCT cis rs2228479 0.702 rs17233253 chr16:89828437 A/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs12497850 0.931 rs11924597 chr3:48937790 T/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs12360000 0.864 rs9919410 chr10:1902486 A/G cg26364871 chr10:1889757 NA -0.41 -4.6 -0.38 1.04e-5 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs896854 0.818 rs896855 chr8:95959808 A/G cg09323728 chr8:95962352 TP53INP1 -0.53 -6.84 -0.52 3.27e-10 Type 2 diabetes; TGCT cis rs2836974 0.644 rs9978775 chr21:40694526 A/G cg17971929 chr21:40555470 PSMG1 -0.65 -5.71 -0.46 8.04e-8 Cognitive function; TGCT cis rs12477438 0.520 rs6542869 chr2:99783403 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs2594989 0.708 rs2594997 chr3:11365739 A/T cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs769267 0.501 rs2074295 chr19:19369435 A/G cg21559469 chr19:19431446 KIAA0892;SF4 0.61 4.52 0.38 1.43e-5 Tonsillectomy; TGCT cis rs4975709 0.959 rs9312959 chr5:1877008 G/A cg14773178 chr5:1868261 NA 0.37 5.32 0.43 4.58e-7 Cardiovascular disease risk factors; TGCT cis rs7044106 0.791 rs10985008 chr9:123492960 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 5.38 0.43 3.65e-7 Hip circumference adjusted for BMI; TGCT cis rs17376456 0.877 rs17083462 chr5:93462401 T/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs600231 0.706 rs11227221 chr11:65319265 T/C cg13974409 chr11:65292307 SCYL1 -0.47 -4.46 -0.37 1.84e-5 Bone mineral density; TGCT cis rs6089584 1.000 rs6089584 chr20:60564086 G/C cg06108461 chr20:60628389 TAF4 -0.53 -7.39 -0.55 1.9e-11 Body mass index; TGCT cis rs597539 0.652 rs513359 chr11:68669496 A/T cg04772025 chr11:68637568 NA -0.6 -6.78 -0.52 4.28e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9443189 0.526 rs9359132 chr6:76289553 G/A cg01950844 chr6:76311363 SENP6 0.97 6.1 0.48 1.27e-8 Prostate cancer; TGCT cis rs12142240 0.698 rs7525309 chr1:46809025 G/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs7208859 0.573 rs58920731 chr17:29191746 G/T cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg03264133 chr6:25882463 NA -0.53 -5.65 -0.45 1.06e-7 Height; TGCT cis rs4972806 0.814 rs1446575 chr2:177047801 A/C cg13092806 chr2:177043255 NA 0.54 4.92 0.4 2.71e-6 IgG glycosylation; TGCT cis rs9297145 0.565 rs941001 chr7:98735185 A/T cg05967295 chr7:98741636 SMURF1 -0.68 -8.74 -0.62 1.36e-14 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs9896933 0.775 rs79299098 chr17:80830944 G/A cg20578329 chr17:80767326 TBCD -0.33 -4.67 -0.39 7.66e-6 Bone mineral accretion in asthma (oral corticosteroid dose interaction); TGCT cis rs921968 0.548 rs13427522 chr2:219438359 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg05368731 chr17:41323189 NBR1 1.2 14.59 0.79 1.08e-28 Menopause (age at onset); TGCT trans rs1005277 0.579 rs2505194 chr10:38393881 C/T cg17830980 chr10:43048298 ZNF37B -0.85 -11.24 -0.71 1.2e-20 Extrinsic epigenetic age acceleration; TGCT cis rs9926296 0.687 rs258317 chr16:89732238 C/T cg27121462 chr16:89883253 FANCA -0.54 -4.93 -0.4 2.63e-6 Vitiligo; TGCT cis rs780096 0.587 rs10205219 chr2:27568565 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.36 4.58 0.38 1.12e-5 Total body bone mineral density; TGCT cis rs782590 0.643 rs13009906 chr2:55739434 A/G cg03859395 chr2:55845619 SMEK2 -0.69 -7.05 -0.53 1.09e-10 Metabolic syndrome; TGCT cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg18230493 chr5:56204884 C5orf35 -0.8 -6.33 -0.49 4.08e-9 Type 2 diabetes; TGCT cis rs17387100 0.551 rs2531156 chr4:16017531 C/G cg13480465 chr4:16795757 LDB2 0.41 5.18 0.42 8.53e-7 Suicide attempts in depression or bipolar disorder; TGCT cis rs7246657 0.943 rs4803347 chr19:37848017 G/A cg03233940 chr19:37894644 NA -0.36 -4.68 -0.39 7.53e-6 Coronary artery calcification; TGCT cis rs1371867 0.846 rs1660316 chr8:101333049 T/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs3796352 1.000 rs13072457 chr3:53102389 G/A cg15956490 chr3:53032818 SFMBT1 0.59 6.64 0.51 8.89e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11112613 0.713 rs11112590 chr12:105951376 C/G cg03607813 chr12:105948248 NA -0.46 -5.56 -0.45 1.59e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs4455778 0.580 rs4292637 chr7:49121114 C/T cg26309511 chr7:48887640 NA -0.5 -6.51 -0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs62103177 0.564 rs2115996 chr18:77701007 C/G cg12964065 chr18:77638022 KCNG2 0.32 4.53 0.38 1.36e-5 Opioid sensitivity; TGCT cis rs62064224 0.748 rs72813015 chr17:30693331 T/C cg18200150 chr17:30822561 MYO1D 0.54 7.06 0.54 1.05e-10 Schizophrenia; TGCT cis rs9911578 0.805 rs12601867 chr17:56455260 C/G cg12560992 chr17:57184187 TRIM37 -0.65 -7.32 -0.55 2.77e-11 Intelligence (multi-trait analysis); TGCT cis rs6424115 1.000 rs7515969 chr1:24158398 G/A cg15997130 chr1:24165203 NA -0.92 -10.61 -0.69 4.13e-19 Immature fraction of reticulocytes; TGCT cis rs1371867 0.875 rs1660311 chr8:101330579 C/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs9300255 0.537 rs1619561 chr12:123620268 G/C cg00376283 chr12:123451042 ABCB9 0.73 5.54 0.45 1.71e-7 Neutrophil percentage of white cells; TGCT cis rs6671200 1.000 rs6678964 chr1:95694268 C/T cg03123541 chr1:95699097 RWDD3 0.9 6.7 0.52 6.67e-10 Stearic acid (18:0) levels; TGCT cis rs78456975 0.527 rs11885279 chr2:1560633 T/C cg12573674 chr2:1569213 NA -0.45 -4.76 -0.39 5.37e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs360798 0.532 rs1553832 chr2:63013515 C/G cg17519650 chr2:63277830 OTX1 -0.6 -5.24 -0.43 6.64e-7 Coronary artery disease; TGCT cis rs9534288 0.797 rs2896951 chr13:46581185 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.6 -0.65 1.15e-16 Platelet count; TGCT cis rs137699 0.652 rs2413589 chr22:39755689 C/T cg01416388 chr22:39784598 NA 0.54 4.88 0.4 3.26e-6 IgG glycosylation; TGCT cis rs4455778 0.659 rs10249340 chr7:49036690 T/C cg26309511 chr7:48887640 NA 0.44 5.22 0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs2456568 0.803 rs10831138 chr11:93640468 T/C cg17595323 chr11:93583763 C11orf90 -0.46 -6.24 -0.49 6.46e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7666738 0.830 rs28456179 chr4:98991439 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1982963 1.000 rs4901186 chr14:52509484 G/A cg10843707 chr14:52510701 NID2 -0.43 -6.52 -0.51 1.62e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9916302 0.861 rs644173 chr17:37430519 T/C cg07936489 chr17:37558343 FBXL20 -0.61 -4.7 -0.39 6.9e-6 Glomerular filtration rate (creatinine); TGCT cis rs2708977 0.901 rs3731938 chr2:97166204 A/G cg01950434 chr2:97203154 ARID5A -0.69 -6.27 -0.49 5.43e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9303401 0.659 rs17822908 chr17:56801778 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs739496 0.895 rs2283357 chr12:111897379 G/C cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg04352962 chr1:209979756 IRF6 0.61 4.67 0.39 7.72e-6 Cleft lip with or without cleft palate; TGCT cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg03264133 chr6:25882463 NA -0.51 -5.27 -0.43 5.81e-7 Height; TGCT cis rs1062177 1.000 rs41494545 chr5:151235094 A/G cg12924095 chr5:151150029 G3BP1 -0.35 -5.05 -0.41 1.53e-6 Preschool internalizing problems; TGCT cis rs72781680 0.664 rs2712076 chr2:23993366 T/C cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs36051895 0.664 rs7857081 chr9:5096728 G/A cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.16e-20 Pediatric autoimmune diseases; TGCT cis rs6912958 0.754 rs10755484 chr6:88244648 C/T cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.92 -0.4 2.7e-6 Monocyte percentage of white cells; TGCT cis rs79387448 0.745 rs76720903 chr2:103162826 G/A cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs295137 0.836 rs1217429 chr2:201094151 G/T cg23649088 chr2:200775458 C2orf69 0.34 5.98 0.47 2.18e-8 Asthma (bronchodilator response); TGCT trans rs1814175 0.817 rs10839401 chr11:49876144 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs709400 0.593 rs12898029 chr14:103877884 T/C cg26031613 chr14:104095156 KLC1 -0.82 -8.95 -0.63 4.19e-15 Body mass index; TGCT trans rs1005277 0.579 rs2023351 chr10:38378814 A/G cg27523141 chr10:43048294 ZNF37B 0.73 8.39 0.6 9.23e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg11644478 chr21:40555479 PSMG1 1.03 11.15 0.71 2.01e-20 Cognitive function; TGCT cis rs6540559 0.673 rs17015330 chr1:210012795 T/G cg21951975 chr1:209979733 IRF6 0.64 4.82 0.4 4.12e-6 Cleft lip with or without cleft palate; TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg16325326 chr1:53192061 ZYG11B 0.5 5.56 0.45 1.56e-7 Monocyte count; TGCT cis rs2663905 0.611 rs1509560 chr15:81391713 T/G cg09236163 chr15:81426669 C15orf26 -0.52 -5.58 -0.45 1.47e-7 QT interval (drug interaction); TGCT cis rs1670533 1.000 rs6821725 chr4:1060360 C/G cg27284194 chr4:1044797 NA 0.7 6.04 0.48 1.63e-8 Recombination rate (females); TGCT cis rs9467773 0.649 rs2145318 chr6:26496603 T/A cg02458000 chr6:26745757 NA 0.48 4.49 0.37 1.59e-5 Intelligence (multi-trait analysis); TGCT cis rs10089 0.953 rs1012851 chr5:127360241 T/C cg19767477 chr5:127420684 SLC12A2 -0.42 -4.46 -0.37 1.85e-5 Ileal carcinoids; TGCT cis rs908922 0.676 rs12059256 chr1:152515431 G/A cg20991723 chr1:152506922 NA 0.46 6.17 0.48 8.79e-9 Hair morphology; TGCT cis rs8031584 0.678 rs4779496 chr15:31151054 A/G cg08109568 chr15:31115862 NA -0.38 -5.03 -0.41 1.67e-6 Huntington's disease progression; TGCT cis rs11690935 1.000 rs12053003 chr2:172537350 A/C cg13550731 chr2:172543902 DYNC1I2 1.2 12.91 0.76 1.08e-24 Schizophrenia; TGCT cis rs11239930 0.538 rs59064267 chr1:146560693 G/A cg00044796 chr1:146552390 NA -0.35 -4.5 -0.37 1.54e-5 AIDS progression; TGCT cis rs13188771 0.690 rs164620 chr5:100873498 C/T cg18665594 chr5:101119420 NA 0.44 4.46 0.37 1.83e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs2456568 0.802 rs1395386 chr11:93639331 A/G cg26875233 chr11:93583750 C11orf90 0.48 6.34 0.5 3.8e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7809950 0.678 rs2395869 chr7:106940098 C/A cg23024343 chr7:107201750 COG5 -0.44 -5.93 -0.47 2.83e-8 Coronary artery disease; TGCT cis rs7568458 0.660 rs55692129 chr2:85792404 A/T cg17127132 chr2:85788382 GGCX 0.53 4.69 0.39 7.22e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7568458 0.684 rs3731828 chr2:85806266 C/T cg02493740 chr2:85810744 VAMP5 -0.29 -5.57 -0.45 1.52e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs75686122 0.772 rs117466837 chr8:104612512 T/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs59197085 0.636 rs62479621 chr7:128465246 C/A cg00260937 chr7:128520193 KCP 0.47 5.01 0.41 1.82e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs1403694 1.000 rs1656911 chr3:186439373 T/C cg12454167 chr3:186435060 KNG1 0.42 7.32 0.55 2.77e-11 Blood protein levels; TGCT cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg05025164 chr4:1340916 KIAA1530 0.75 6.26 0.49 5.69e-9 Longevity; TGCT cis rs1499614 1.000 rs2659913 chr7:66157336 T/A cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg22920501 chr2:26401640 FAM59B 0.71 5.59 0.45 1.36e-7 Gut microbiome composition (summer); TGCT cis rs909674 0.818 rs5757681 chr22:39845547 A/G cg02038168 chr22:39784481 NA -0.71 -5.49 -0.44 2.21e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs694739 0.541 rs61886926 chr11:64133552 C/T cg02228329 chr11:64053129 BAD;GPR137 0.69 6.71 0.52 6.1e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs11785693 0.862 rs17351027 chr8:4987098 A/G cg26367366 chr8:4980734 NA -0.57 -4.49 -0.37 1.61e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs9467773 0.935 rs4573 chr6:26546808 A/G cg26531700 chr6:26746687 NA 0.63 6.59 0.51 1.15e-9 Intelligence (multi-trait analysis); TGCT cis rs904251 0.861 rs1757171 chr6:37487044 T/C cg01843034 chr6:37503916 NA -0.51 -6.1 -0.48 1.22e-8 Cognitive performance; TGCT cis rs79057730 0.599 rs34411410 chr7:811721 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.64 5.23 0.43 6.91e-7 Initial pursuit acceleration; TGCT cis rs6089829 0.962 rs9680064 chr20:61666168 G/A cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs2404602 0.692 rs12913810 chr15:77166675 T/C cg26408565 chr15:76604113 ETFA -0.36 -4.52 -0.38 1.41e-5 Blood metabolite levels; TGCT cis rs2115630 0.645 rs3825877 chr15:85174631 G/A cg11189052 chr15:85197271 WDR73 -0.76 -7.38 -0.55 1.99e-11 P wave terminal force; TGCT cis rs2404602 0.709 rs11072591 chr15:76649562 A/G cg22467129 chr15:76604101 ETFA -0.5 -5.41 -0.44 3.15e-7 Blood metabolite levels; TGCT cis rs2458413 0.542 rs2458430 chr8:105367785 C/T cg04554929 chr8:105342491 NA -0.49 -5.79 -0.46 5.35e-8 Paget's disease; TGCT cis rs7824557 0.564 rs2572404 chr8:11199584 A/G cg21775007 chr8:11205619 TDH 0.73 6.81 0.52 3.72e-10 Retinal vascular caliber; TGCT cis rs6456156 0.792 rs7775443 chr6:167513252 A/C cg07741184 chr6:167504864 NA -0.22 -4.51 -0.38 1.48e-5 Primary biliary cholangitis; TGCT cis rs11671005 0.616 rs12980907 chr19:58956326 C/T cg07777224 chr19:58919807 ZNF584 -0.63 -4.47 -0.37 1.77e-5 Mean platelet volume; TGCT cis rs709400 0.628 rs11622356 chr14:103912195 C/T cg12935359 chr14:103987150 CKB -0.34 -4.95 -0.41 2.34e-6 Body mass index; TGCT cis rs9952991 0.883 rs11663253 chr18:12789556 A/G cg24737193 chr18:12778029 NA -0.51 -5.39 -0.44 3.45e-7 Inflammatory skin disease; TGCT cis rs7940866 0.845 rs2324314 chr11:130834589 A/C cg05962950 chr11:130786565 SNX19 0.69 7.0 0.53 1.42e-10 Schizophrenia; TGCT cis rs1153858 1.000 rs1618874 chr15:45622786 A/G cg14582100 chr15:45693742 SPATA5L1 0.47 5.59 0.45 1.39e-7 Homoarginine levels; TGCT cis rs9914544 0.966 rs7210746 chr17:18798593 T/C cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.41 1.36e-6 Educational attainment (years of education); TGCT cis rs7226408 0.857 rs72885302 chr18:34453491 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2777491 0.872 rs61037359 chr15:41585926 T/C cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.86 -0.7 9.98e-20 Ulcerative colitis; TGCT cis rs7086627 0.507 rs7077907 chr10:82017082 A/G cg01528321 chr10:82214614 TSPAN14 0.62 5.68 0.45 9.18e-8 Post bronchodilator FEV1; TGCT cis rs1894292 0.527 rs10938079 chr4:74375473 C/T cg05868023 chr4:75230803 EREG 0.53 4.67 0.39 7.56e-6 Prostate cancer; TGCT cis rs920590 0.510 rs4922101 chr8:19648895 A/G cg03894339 chr8:19674705 INTS10 0.82 5.29 0.43 5.28e-7 Acute lymphoblastic leukemia (childhood); TGCT cis rs6912958 0.754 rs2268994 chr6:88185386 A/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.08 -0.41 1.36e-6 Monocyte percentage of white cells; TGCT cis rs4076764 1.000 rs7528020 chr1:163426537 G/A cg24596788 chr1:163392923 NA -0.17 -4.75 -0.39 5.46e-6 Motion sickness; TGCT cis rs7829975 0.774 rs11775523 chr8:8679176 A/G cg06636001 chr8:8085503 FLJ10661 0.68 5.98 0.47 2.17e-8 Mood instability; TGCT cis rs4253772 0.591 rs6007747 chr22:46657261 A/G cg09491104 chr22:46646882 C22orf40 -0.63 -6.39 -0.5 3.05e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs3796352 1.000 rs11707575 chr3:53113762 G/T cg07884673 chr3:53033167 SFMBT1 0.48 4.97 0.41 2.13e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10782582 0.609 rs5745394 chr1:76311731 G/A cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs4629710 0.568 rs9492883 chr6:131573872 A/T cg12606694 chr6:131520996 AKAP7 0.41 4.82 0.4 4.09e-6 Multiple myeloma (IgH translocation); TGCT cis rs908922 0.676 rs486283 chr1:152525957 A/G cg20991723 chr1:152506922 NA 0.45 6.06 0.48 1.55e-8 Hair morphology; TGCT cis rs1371867 0.875 rs1660311 chr8:101330579 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs9357506 0.846 rs2396640 chr6:46309620 A/G cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs12765878 0.580 rs55983834 chr10:105601210 C/T cg11005552 chr10:105648138 OBFC1 -0.39 -6.05 -0.48 1.6e-8 Coronary artery disease; TGCT cis rs2455799 0.613 rs2455813 chr3:15735051 C/G cg16303742 chr3:15540471 COLQ -0.24 -4.51 -0.38 1.47e-5 Mean platelet volume; TGCT cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs12136530 0.593 rs12121189 chr1:19740421 G/A cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs483180 0.512 rs598685 chr1:120215269 G/A cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Macular telangiectasia type 2; TGCT cis rs4242434 0.927 rs3736147 chr8:22471824 A/G cg03733263 chr8:22462867 KIAA1967 -1.15 -20.1 -0.87 7.99e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs916888 0.773 rs199439 chr17:44793503 A/G cg01570182 chr17:44337453 NA 1.08 9.48 0.65 2.25e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs112591243 0.504 rs73381504 chr21:48027668 G/T cg23283320 chr21:48055893 PRMT2 0.7 4.99 0.41 1.99e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs986417 1.000 rs7160408 chr14:60977471 A/G cg27398547 chr14:60952738 C14orf39 1.42 9.26 0.64 7.81e-16 Gut microbiota (bacterial taxa); TGCT cis rs6121246 0.697 rs6087716 chr20:30229040 C/T cg21427119 chr20:30132790 HM13 -0.37 -5.19 -0.42 8.51e-7 Mean corpuscular hemoglobin; TGCT cis rs10992471 0.528 rs10117627 chr9:95203953 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7666738 0.546 rs13105521 chr4:98734419 C/T cg18180107 chr4:99064573 C4orf37 0.51 4.55 0.38 1.28e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2730245 0.959 rs2527201 chr7:158738611 G/T cg11984989 chr7:158649758 WDR60 -0.97 -8.97 -0.63 3.94e-15 Height; TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs11190604 0.943 rs11190574 chr10:102234331 T/C cg23241863 chr10:102295624 HIF1AN 0.64 4.85 0.4 3.56e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7582180 0.629 rs4851308 chr2:100971865 C/A cg14675211 chr2:100938903 LONRF2 0.5 4.79 0.4 4.66e-6 Intelligence (multi-trait analysis); TGCT cis rs6040399 1.000 rs6040398 chr20:11156550 C/T cg07941953 chr20:10508668 C20orf94 -0.31 -4.58 -0.38 1.13e-5 Response to citalopram treatment; TGCT cis rs2562456 0.837 rs62110205 chr19:21760071 A/G cg01304269 chr19:21688519 ZNF429 0.58 4.46 0.37 1.84e-5 Pain; TGCT cis rs9928842 0.664 rs9921632 chr16:75220263 C/T cg09066997 chr16:75300724 BCAR1 0.22 4.44 0.37 1.98e-5 Alcoholic chronic pancreatitis; TGCT cis rs2463822 0.920 rs11828383 chr11:62067818 C/T cg23876832 chr11:62092739 NA -0.74 -4.85 -0.4 3.59e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs422249 0.512 rs174546 chr11:61569830 C/T cg19610905 chr11:61596333 FADS2 -1.09 -11.84 -0.73 4.21e-22 Trans fatty acid levels; TGCT cis rs12497850 0.966 rs6792510 chr3:48723302 G/C cg18654377 chr3:49208889 KLHDC8B -0.41 -5.43 -0.44 2.84e-7 Parkinson's disease; TGCT cis rs904251 0.797 rs1757181 chr6:37485728 A/G cg25019722 chr6:37503610 NA 0.48 6.62 0.51 9.78e-10 Cognitive performance; TGCT cis rs4631830 0.863 rs4486572 chr10:51531805 A/G cg10326726 chr10:51549505 MSMB -0.25 -4.9 -0.4 2.88e-6 Prostate-specific antigen levels; TGCT trans rs1814175 0.817 rs11040651 chr11:49938395 G/A cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs302972 0.826 rs9461103 chr6:25099116 C/T cg18428180 chr6:24646492 KIAA0319 0.98 4.45 0.37 1.91e-5 Creatinine levels in ischemic stroke; TGCT cis rs2180341 0.883 rs9388568 chr6:127690694 C/A cg27446573 chr6:127587934 RNF146 1.1 10.61 0.69 4.22e-19 Breast cancer; TGCT cis rs9926296 0.682 rs645019 chr16:89716883 C/T cg04287289 chr16:89883240 FANCA -0.53 -4.96 -0.41 2.24e-6 Vitiligo; TGCT cis rs2458413 1.000 rs2458413 chr8:105359432 C/T cg04554929 chr8:105342491 NA 0.52 7.14 0.54 6.76e-11 Paget's disease; TGCT cis rs6163 0.727 rs284854 chr10:104574562 T/G cg04362960 chr10:104952993 NT5C2 -0.53 -4.66 -0.39 8.04e-6 Waist circumference;Hip circumference; TGCT cis rs597480 0.963 rs589327 chr11:85446226 A/G cg11817631 chr11:85522609 SYTL2 -0.44 -4.45 -0.37 1.89e-5 Drug-induced liver injury (nonsteroidal anti-inflammatory drugs); TGCT cis rs10484885 0.878 rs111664889 chr6:90566427 G/T cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2820315 0.931 rs2644114 chr1:201864830 A/G cg12730843 chr1:201915899 LMOD1 0.27 4.81 0.4 4.25e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs7923609 0.967 rs7095571 chr10:65150959 T/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.16e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2073300 1.000 rs6137966 chr20:23444359 A/T cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs155076 1.000 rs598754 chr13:21845010 C/A cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg06481639 chr22:41940642 POLR3H -0.6 -5.43 -0.44 2.89e-7 Vitiligo; TGCT cis rs2302045 1.000 rs3815292 chr2:242032762 A/G cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs12908161 0.960 rs17599989 chr15:85285536 A/G cg12863693 chr15:85201151 NMB 0.43 5.15 0.42 9.84e-7 Schizophrenia; TGCT cis rs2742417 1.000 rs2742452 chr3:45765708 C/T cg04837898 chr3:45731254 SACM1L -0.52 -5.28 -0.43 5.58e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9297145 0.958 rs11975761 chr7:98766688 G/A cg05967295 chr7:98741636 SMURF1 -1.03 -16.21 -0.82 1.99e-32 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs875971 0.862 rs801194 chr7:66028495 T/C cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs9467711 1.000 rs6903015 chr6:26322526 A/G cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs79149102 0.579 rs6495146 chr15:75367630 A/T cg09165964 chr15:75287851 SCAMP5 -1.03 -5.69 -0.45 8.73e-8 Lung cancer; TGCT cis rs9517313 0.592 rs61969458 chr13:99177633 A/G cg07423050 chr13:99094983 FARP1 -0.29 -5.49 -0.44 2.22e-7 Neuroticism; TGCT cis rs617219 0.698 rs7379187 chr5:78521354 T/C cg23987322 chr5:78407566 BHMT 0.37 5.12 0.42 1.14e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs698813 0.604 rs768006 chr2:44487612 C/G cg00619915 chr2:44497795 NA -0.25 -5.7 -0.46 8.4e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs12134133 1.000 rs2782850 chr1:207465437 A/T cg02152968 chr1:207494213 CD55 0.57 4.47 0.37 1.74e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs11935103 0.569 rs10022988 chr4:187291021 T/C cg16785698 chr4:186456103 PDLIM3 0.45 4.58 0.38 1.14e-5 Response to citalopram treatment; TGCT trans rs7618501 0.966 rs2246832 chr3:49881134 A/T cg21659725 chr3:3221576 CRBN 0.98 15.34 0.81 2.02e-30 Intelligence (multi-trait analysis); TGCT cis rs2307449 0.929 rs9788714 chr15:89781855 G/A cg24365117 chr15:89879190 POLG 0.35 4.46 0.37 1.81e-5 Menopause (age at onset); TGCT cis rs7100689 0.753 rs2185426 chr10:82120887 G/A cg01528321 chr10:82214614 TSPAN14 0.88 8.48 0.61 5.61e-14 Post bronchodilator FEV1; TGCT cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg09177884 chr7:1199841 ZFAND2A -0.51 -4.9 -0.4 2.98e-6 Longevity;Endometriosis; TGCT cis rs12579753 1.000 rs10862372 chr12:82249804 C/T cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs7959452 0.535 rs10878953 chr12:69674187 A/G cg20891283 chr12:69753455 YEATS4 0.62 5.94 0.47 2.74e-8 Blood protein levels; TGCT cis rs4689388 0.750 rs10001190 chr4:6284633 C/T cg14416269 chr4:6271139 WFS1 -0.38 -5.12 -0.42 1.13e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg03517284 chr6:25882590 NA 0.82 8.28 0.6 1.68e-13 Blood metabolite levels; TGCT cis rs4820539 1.000 rs885963 chr22:23460939 G/T cg21100191 chr22:23484243 RTDR1 0.94 11.14 0.71 2.17e-20 Bone mineral density; TGCT cis rs1532993 0.518 rs1545598 chr4:98633592 T/G cg05340658 chr4:99064831 C4orf37 -0.4 -4.91 -0.4 2.77e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs826838 1.000 rs11168505 chr12:38939057 A/T cg13010199 chr12:38710504 ALG10B -0.65 -5.46 -0.44 2.52e-7 Heart rate; TGCT cis rs3733585 0.673 rs6849729 chr4:9958732 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg19318889 chr4:1322082 MAEA 0.2 4.58 0.38 1.1e-5 Longevity; TGCT cis rs910316 0.967 rs4899550 chr14:75647666 C/T cg11812906 chr14:75593930 NEK9 -0.72 -7.1 -0.54 8.47e-11 Height; TGCT cis rs394563 0.591 rs237018 chr6:149743930 A/G cg11245181 chr6:149772854 ZC3H12D -0.28 -4.5 -0.37 1.54e-5 Dupuytren's disease; TGCT cis rs4555082 0.874 rs4677 chr14:105717279 T/C cg01266790 chr14:105781312 PACS2 0.54 4.5 0.37 1.53e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs1218582 0.804 rs4845678 chr1:154853295 A/G cg03351412 chr1:154909251 PMVK 0.52 4.83 0.4 3.96e-6 Prostate cancer; TGCT cis rs7666738 0.791 rs7678564 chr4:99057341 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8180040 0.966 rs13075233 chr3:47420627 T/C cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs826838 0.900 rs1403523 chr12:39130570 T/A cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs6840360 0.533 rs13119490 chr4:152713412 A/G cg22705602 chr4:152727874 NA 0.34 5.98 0.47 2.2e-8 Intelligence (multi-trait analysis); TGCT cis rs2288073 0.930 rs7604097 chr2:24401805 G/C cg02683114 chr2:24398427 C2orf84 -0.24 -5.72 -0.46 7.53e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs4975709 0.569 rs2353583 chr5:1858834 G/C cg15595755 chr5:1867978 NA 0.46 5.21 0.42 7.54e-7 Cardiovascular disease risk factors; TGCT cis rs7918232 1.000 rs6482595 chr10:27380261 A/G cg15469871 chr10:27541418 LOC387646 -0.51 -4.6 -0.38 1.02e-5 Breast cancer; TGCT cis rs875971 1.000 rs1565531 chr7:65663113 T/A cg11764359 chr7:65958608 NA -0.61 -5.35 -0.43 4.05e-7 Aortic root size; TGCT cis rs6831352 0.918 rs17817958 chr4:100061245 A/C cg12011299 chr4:100065546 ADH4 0.45 5.16 0.42 9.65e-7 Alcohol dependence; TGCT cis rs7937682 0.889 rs521155 chr11:111492563 G/A cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs208515 0.525 rs10755508 chr6:66675790 T/C cg07460842 chr6:66804631 NA 0.87 9.16 0.64 1.32e-15 Exhaled nitric oxide levels; TGCT cis rs7945705 0.747 rs2568020 chr11:8994715 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -4.97 -0.41 2.16e-6 Hemoglobin concentration; TGCT cis rs6952808 1.000 rs10260585 chr7:1889521 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.63 -0.45 1.13e-7 Bipolar disorder and schizophrenia; TGCT cis rs422249 0.511 rs102274 chr11:61557826 T/C cg01500311 chr11:61656094 FADS3 -0.34 -5.93 -0.47 2.8e-8 Trans fatty acid levels; TGCT cis rs7552404 0.731 rs931507 chr1:76401577 G/A cg10523679 chr1:76189770 ACADM -0.8 -7.4 -0.55 1.79e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12368653 0.789 rs2270777 chr12:58145156 C/T cg12615879 chr12:58013172 SLC26A10 0.53 6.58 0.51 1.17e-9 Multiple sclerosis; TGCT cis rs7226408 0.857 rs56364983 chr18:34430275 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2842992 0.872 rs9456440 chr6:160074463 G/T cg11366901 chr6:160182831 ACAT2 1.02 6.71 0.52 6.06e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs9486715 0.867 rs9480700 chr6:96965056 A/G cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs28595532 0.920 rs56342843 chr4:119765070 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs514406 0.584 rs7524702 chr1:53197830 G/A cg08859206 chr1:53392774 SCP2 0.34 4.83 0.4 4.01e-6 Monocyte count; TGCT cis rs4727027 0.901 rs6943937 chr7:148869915 A/G cg23583168 chr7:148888333 NA -0.75 -9.82 -0.66 3.48e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9436747 0.667 rs4370791 chr1:66052228 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.82 0.4 4.14e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs10779751 1.000 rs742824 chr1:11274022 G/A cg08854313 chr1:11322531 MTOR 0.91 9.86 0.66 2.71e-17 Body mass index; TGCT cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg12310025 chr6:25882481 NA 0.54 5.41 0.44 3.11e-7 Blood metabolite levels; TGCT cis rs7804356 1.000 rs10229837 chr7:26840652 G/A cg03456212 chr7:26904342 SKAP2 -0.61 -4.7 -0.39 6.82e-6 Type 1 diabetes; TGCT cis rs5758659 0.714 rs5751216 chr22:42508937 G/T cg15557168 chr22:42548783 NA 0.18 4.63 0.38 9.14e-6 Cognitive function; TGCT cis rs1347297 0.526 rs6757186 chr2:179259719 G/C cg03991736 chr2:179345203 MIR548N;PLEKHA3 -0.51 -5.01 -0.41 1.86e-6 Alzheimer disease and age of onset; TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg17546649 chr3:44802566 KIF15;KIAA1143 -0.36 -4.44 -0.37 1.99e-5 Depressive symptoms; TGCT cis rs7666738 0.830 rs35644814 chr4:98886111 G/C cg17366294 chr4:99064904 C4orf37 0.68 6.87 0.53 2.72e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1215050 0.791 rs548892 chr4:98724701 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.57 0.45 1.54e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611519 0.580 rs8138349 chr22:41412723 C/T cg06634786 chr22:41940651 POLR3H -0.49 -4.54 -0.38 1.33e-5 Neuroticism; TGCT cis rs7819412 0.805 rs4333549 chr8:10979561 C/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.68 -0.39 7.39e-6 Triglycerides; TGCT cis rs539096 1.000 rs539096 chr1:44072420 C/T cg12908607 chr1:44402522 ARTN 0.51 5.43 0.44 2.89e-7 Intelligence (multi-trait analysis); TGCT cis rs7106204 0.748 rs28656439 chr11:24207653 G/C ch.11.24196551F chr11:24239977 NA 0.47 4.45 0.37 1.91e-5 Response to Homoharringtonine (cytotoxicity); TGCT trans rs10506458 1.000 rs1495013 chr12:63428188 C/T cg22491629 chr6:157744540 C6orf35 -0.97 -8.42 -0.6 7.88e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs7843479 0.965 rs11135763 chr8:21813962 A/G cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs6534347 0.573 rs9992580 chr4:123526195 T/G cg10583651 chr4:123538969 IL21 -0.33 -4.9 -0.4 2.99e-6 Type 1 diabetes; TGCT cis rs903263 0.601 rs12132032 chr1:84566589 A/G cg09664975 chr1:84543551 PRKACB 0.5 4.86 0.4 3.47e-6 Breast cancer (male); TGCT cis rs1799949 0.965 rs9897425 chr17:41430179 C/G cg10047753 chr17:41438598 NA 0.81 7.71 0.57 3.5e-12 Menopause (age at onset); TGCT cis rs7178572 0.568 rs8030074 chr15:77654232 C/T cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs2120019 0.935 rs8042409 chr15:75350433 G/A cg09165964 chr15:75287851 SCAMP5 -1.18 -10.44 -0.68 1.07e-18 Blood trace element (Zn levels); TGCT cis rs3087591 0.960 rs2953012 chr17:29496486 A/G cg24425628 chr17:29625626 OMG;NF1 0.45 7.23 0.54 4.41e-11 Hip circumference; TGCT cis rs2839186 0.872 rs13046834 chr21:47701485 T/C cg13732083 chr21:47605072 C21orf56 0.34 4.52 0.38 1.44e-5 Testicular germ cell tumor; TGCT cis rs9303401 0.659 rs35797125 chr17:56736547 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs611744 0.538 rs59930666 chr8:109262296 T/C cg21045802 chr8:109455806 TTC35 0.8 8.25 0.6 1.98e-13 Dupuytren's disease; TGCT cis rs2404602 0.647 rs12914196 chr15:76941361 C/T cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs227917 1.000 rs10257096 chr7:23691283 C/G cg12601843 chr7:23510954 IGF2BP3 0.58 4.66 0.39 8.1e-6 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs75229567 0.717 rs17107156 chr12:70234066 A/G cg10114359 chr12:70132523 RAB3IP -1.55 -7.66 -0.57 4.5e-12 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs6840360 0.582 rs2709827 chr4:152331252 G/C cg17479576 chr4:152424074 FAM160A1 -0.56 -5.85 -0.46 4.13e-8 Intelligence (multi-trait analysis); TGCT cis rs4074961 0.509 rs4653300 chr1:38024054 A/G cg11397548 chr1:38022522 DNALI1 0.41 5.09 0.42 1.28e-6 Axial length; TGCT cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg04546413 chr19:29218101 NA 0.84 6.82 0.52 3.52e-10 Methadone dose in opioid dependence; TGCT cis rs9913156 0.793 rs11568061 chr17:4546445 G/A cg23387401 chr17:4582204 PELP1 0.32 4.73 0.39 5.96e-6 Lymphocyte counts; TGCT cis rs6964587 0.934 rs12531561 chr7:91707780 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs8062405 0.964 rs11860513 chr16:28825420 C/T cg09754948 chr16:28834200 ATXN2L 0.63 4.73 0.39 6.03e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9611565 0.559 rs132768 chr22:42013523 C/A cg13695892 chr22:41940480 POLR3H 0.88 8.46 0.6 6.38e-14 Vitiligo; TGCT cis rs1949733 0.655 rs2631736 chr4:8478421 C/G cg11789530 chr4:8429930 ACOX3 -0.57 -5.32 -0.43 4.68e-7 Response to antineoplastic agents; TGCT cis rs12908161 0.960 rs17599989 chr15:85285536 A/G cg11189052 chr15:85197271 WDR73 0.68 5.65 0.45 1.03e-7 Schizophrenia; TGCT cis rs6088590 1.000 rs6119535 chr20:33442138 A/C cg06115741 chr20:33292138 TP53INP2 0.62 5.09 0.42 1.28e-6 Coronary artery disease; TGCT cis rs6048205 0.764 rs1203905 chr20:22560689 A/G cg10773670 chr20:23331356 NXT1 -0.97 -4.66 -0.39 8.05e-6 Fasting blood glucose (BMI interaction);Fasting blood glucose; TGCT cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs1218582 0.774 rs12036859 chr1:154859940 A/C cg06418219 chr1:154948305 SHC1;CKS1B 0.64 6.44 0.5 2.41e-9 Prostate cancer; TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs4389656 0.857 rs274677 chr5:6754402 T/C cg10857441 chr5:6722123 POLS -0.21 -4.6 -0.38 1.03e-5 Coronary artery disease; TGCT cis rs11785400 0.793 rs1137521 chr8:143739162 C/T cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs4924935 1.000 rs4924935 chr17:18753870 C/T cg26378065 chr17:18585709 ZNF286B 0.57 4.8 0.4 4.44e-6 Pancreatic cancer; TGCT cis rs3784262 0.565 rs12595410 chr15:58293040 A/G cg12031962 chr15:58353849 ALDH1A2 0.39 5.56 0.45 1.57e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs12510870 0.634 rs2178292 chr4:74384761 T/C cg05868023 chr4:75230803 EREG 0.55 4.7 0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs28595532 0.920 rs116405053 chr4:119739352 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs9660992 0.762 rs1668871 chr1:205237137 T/C cg00857998 chr1:205179979 DSTYK 0.51 4.71 0.39 6.47e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs6688613 0.729 rs10918603 chr1:166936503 T/C cg07049167 chr1:166818506 POGK 0.27 5.16 0.42 9.39e-7 Refractive astigmatism; TGCT cis rs6723226 0.552 rs62136336 chr2:32804106 G/A cg02381751 chr2:32503542 YIPF4 0.5 4.53 0.38 1.34e-5 Intelligence (multi-trait analysis); TGCT cis rs765787 0.530 rs16941017 chr15:45543281 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.49 -0.44 2.16e-7 Uric acid levels; TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg03404566 chr17:6899310 ALOX12 0.45 5.11 0.42 1.17e-6 Tonsillectomy; TGCT cis rs1865760 0.865 rs9467645 chr6:25955176 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs1691799 0.867 rs1027401 chr12:66760892 C/G cg16791601 chr12:66731901 HELB -0.28 -6.03 -0.48 1.74e-8 White blood cell count (basophil); TGCT cis rs11098499 0.687 rs71610270 chr4:120287436 A/G cg09307838 chr4:120376055 NA 0.54 5.08 0.41 1.37e-6 Corneal astigmatism; TGCT cis rs1555895 0.576 rs10904571 chr10:850762 A/G cg02193355 chr10:851439 NA 0.22 4.86 0.4 3.54e-6 Survival in rectal cancer; TGCT cis rs3008870 0.536 rs2208576 chr1:67513401 C/G cg08660285 chr1:67390436 MIER1;WDR78 -0.67 -6.51 -0.5 1.72e-9 Lymphocyte percentage of white cells; TGCT cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs13191362 0.507 rs2846519 chr6:163045463 G/A cg06582575 chr6:163149167 PACRG;PARK2 -0.59 -5.79 -0.46 5.55e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs35306767 0.761 rs11253540 chr10:1011958 C/T cg26597838 chr10:835615 NA -0.57 -6.62 -0.51 9.89e-10 Eosinophil percentage of granulocytes; TGCT cis rs9811920 0.599 rs1688758 chr3:99539890 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 7.02 0.53 1.32e-10 Axial length; TGCT cis rs12210905 0.920 rs858995 chr6:27181701 T/C cg08851530 chr6:28072375 NA -0.96 -4.73 -0.39 5.89e-6 Hip circumference adjusted for BMI; TGCT cis rs7614311 0.636 rs73117059 chr3:63916028 A/G cg22134162 chr3:63841271 THOC7 -0.49 -6.17 -0.48 8.78e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs10464366 0.544 rs4355688 chr7:39158402 C/T cg18850127 chr7:39170497 POU6F2 0.33 7.16 0.54 6.13e-11 IgG glycosylation; TGCT cis rs2235642 0.821 rs8051895 chr16:1602811 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.64 -0.45 1.08e-7 Coronary artery disease; TGCT cis rs9325144 0.560 rs7980635 chr12:38668355 G/T cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs12048904 0.619 rs10875347 chr1:101333737 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.83 8.07 0.59 5.08e-13 Multiple sclerosis; TGCT cis rs7617773 0.780 rs13067450 chr3:48337206 C/T cg11946769 chr3:48343235 NME6 0.82 7.06 0.54 1.03e-10 Coronary artery disease; TGCT cis rs6921919 0.515 rs1339898 chr6:28395506 C/T cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.49 -0.37 1.63e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9894429 0.646 rs7210026 chr17:79612382 T/C cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs12210905 0.687 rs72843622 chr6:27161152 C/T cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg12751644 chr20:60527061 NA -0.52 -7.06 -0.54 1.07e-10 Obesity-related traits; TGCT cis rs612683 0.826 rs7556246 chr1:100828914 A/G cg06223162 chr1:101003688 GPR88 0.29 4.99 0.41 1.97e-6 Breast cancer; TGCT cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs116095464 0.558 rs56342538 chr5:225796 T/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs6089584 0.606 rs2296082 chr20:60573983 A/G cg06108461 chr20:60628389 TAF4 -0.4 -4.86 -0.4 3.46e-6 Body mass index; TGCT cis rs7312933 0.558 rs11181483 chr12:42798384 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 4.97 0.41 2.2e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7666738 0.830 rs113999196 chr4:99041961 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs425277 0.606 rs262663 chr1:2084598 T/C cg03732007 chr1:2071316 PRKCZ 0.28 6.63 0.51 9.05e-10 Height; TGCT cis rs2075371 0.674 rs11771785 chr7:134013249 A/G cg11752832 chr7:134001865 SLC35B4 -0.64 -5.22 -0.42 7.36e-7 Mean platelet volume; TGCT cis rs2839186 0.732 rs55904887 chr21:47707811 A/G cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs9611565 0.592 rs5758405 chr22:42076381 C/A cg06481639 chr22:41940642 POLR3H 0.73 6.62 0.51 9.76e-10 Vitiligo; TGCT cis rs769267 0.930 rs2288852 chr19:19605348 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs992157 0.932 rs56109829 chr2:219149740 G/A cg00012203 chr2:219082015 ARPC2 0.8 8.47 0.61 5.95e-14 Colorectal cancer; TGCT cis rs9527 0.590 rs3781281 chr10:104852648 A/G cg15744005 chr10:104629667 AS3MT 0.42 4.96 0.41 2.27e-6 Arsenic metabolism; TGCT cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg13683864 chr3:40499215 RPL14 -1.17 -13.09 -0.76 4.01e-25 Renal cell carcinoma; TGCT cis rs36051895 0.586 rs12342421 chr9:5065750 G/C cg02405213 chr9:5042618 JAK2 -0.74 -9.76 -0.66 4.79e-17 Pediatric autoimmune diseases; TGCT cis rs5750830 0.546 rs4821891 chr22:39785381 C/T cg01416388 chr22:39784598 NA -0.74 -7.49 -0.56 1.1e-11 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.790 rs66488313 chr6:26631568 G/T cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9611519 1.000 rs6002271 chr22:41566595 C/T cg03806693 chr22:41940476 POLR3H -0.67 -6.1 -0.48 1.23e-8 Neuroticism; TGCT cis rs13168506 0.538 rs12521857 chr5:135440364 G/A cg16684184 chr5:135415129 NA -0.25 -4.44 -0.37 1.99e-5 Stroke; TGCT cis rs617219 0.698 rs7445125 chr5:78507417 A/G cg23514016 chr5:78407564 BHMT 0.35 5.34 0.43 4.24e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs12681288 0.782 rs12549337 chr8:1030187 A/G cg04851639 chr8:1020857 NA -0.35 -6.24 -0.49 6.21e-9 Schizophrenia; TGCT cis rs12477438 0.700 rs12467679 chr2:99654449 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg14159672 chr1:205819179 PM20D1 0.63 7.96 0.58 9.34e-13 Menarche (age at onset); TGCT cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs763121 0.785 rs5750646 chr22:39013830 T/C cg06022373 chr22:39101656 GTPBP1 0.81 8.37 0.6 9.98e-14 Menopause (age at onset); TGCT cis rs4523957 0.615 rs59207721 chr17:2070479 C/A cg16513277 chr17:2031491 SMG6 -0.21 -4.69 -0.39 7e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs17826219 0.500 rs61685770 chr17:29085713 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.63e-9 Blood metabolite levels; TGCT cis rs78487399 0.808 rs74821293 chr2:43742923 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.61 -0.38 9.77e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12540874 0.529 rs732215 chr7:50544063 A/C cg18232548 chr7:50535776 DDC -0.36 -6.28 -0.49 5.26e-9 Systemic sclerosis; TGCT cis rs2204008 0.529 rs1315350 chr12:38164282 C/A cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs1865760 0.713 rs9461229 chr6:25992279 G/T cg16482183 chr6:26056742 HIST1H1C 0.54 4.77 0.39 5.15e-6 Height; TGCT cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.830 rs1426668 chr4:98945585 T/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1153858 0.895 rs12593402 chr15:45617392 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.66 0.45 9.96e-8 Homoarginine levels; TGCT cis rs1801251 0.835 rs1446310 chr2:233683245 G/C cg25237894 chr2:233734115 C2orf82 -0.3 -5.45 -0.44 2.63e-7 Coronary artery disease; TGCT cis rs514406 0.607 rs6696940 chr1:53203427 C/T cg01802117 chr1:53393560 SCP2 0.44 5.16 0.42 9.62e-7 Monocyte count; TGCT cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg13695892 chr22:41940480 POLR3H -0.83 -7.68 -0.57 4.15e-12 Vitiligo; TGCT cis rs17376456 0.877 rs9314100 chr5:93447394 T/C cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs2730245 0.636 rs2657382 chr7:158650941 G/A cg24397884 chr7:158709396 WDR60 0.35 4.55 0.38 1.26e-5 Height; TGCT cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs1691799 0.899 rs1168305 chr12:66738714 A/G cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs7267979 0.934 rs4815423 chr20:25387521 A/G cg03522245 chr20:25566470 NINL -0.63 -6.78 -0.52 4.39e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9916302 0.706 rs597069 chr17:37458512 G/T cg07936489 chr17:37558343 FBXL20 0.84 6.16 0.48 9.3e-9 Glomerular filtration rate (creatinine); TGCT cis rs9807989 0.507 rs10439410 chr2:102990788 A/C cg03938978 chr2:103052716 IL18RAP -0.26 -5.22 -0.42 7.15e-7 Asthma; TGCT cis rs10193935 0.901 rs3755304 chr2:42589921 A/G cg27598129 chr2:42591480 NA 0.37 5.13 0.42 1.09e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs473651 0.901 rs563282 chr2:239329736 T/C cg08773314 chr2:239334832 ASB1 0.49 7.84 0.58 1.72e-12 Multiple system atrophy; TGCT cis rs2730260 0.500 rs73169244 chr7:158887293 T/C cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs6582630 0.555 rs7133706 chr12:38475465 G/A cg13010199 chr12:38710504 ALG10B -0.54 -4.44 -0.37 1.95e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs11249608 0.548 rs62393076 chr5:178450646 C/G cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT trans rs6089829 0.962 rs57684920 chr20:61662639 G/A cg13615516 chr5:77269221 NA -0.67 -8.09 -0.59 4.7e-13 Prostate cancer (SNP x SNP interaction); TGCT trans rs6089829 0.962 rs9679865 chr20:61666132 C/G cg13615516 chr5:77269221 NA 0.69 8.57 0.61 3.51e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs922182 0.556 rs12443020 chr15:64215823 G/T cg02919090 chr15:64263738 DAPK2 0.37 6.77 0.52 4.69e-10 Blood protein levels; TGCT cis rs1451375 0.698 rs7797131 chr7:50647934 A/G cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs72615157 0.634 rs79986079 chr7:99802044 C/T cg00814883 chr7:100076585 TSC22D4 -0.52 -5.05 -0.41 1.54e-6 Lung function (FEV1/FVC); TGCT cis rs9921338 0.923 rs72771877 chr16:11368616 T/A cg00044050 chr16:11439710 C16orf75 -0.84 -5.42 -0.44 3.05e-7 Vein graft stenosis in coronary artery bypass grafting; TGCT trans rs1814175 0.817 rs10769598 chr11:49669326 C/G cg11707556 chr5:10655725 ANKRD33B -0.38 -7.7 -0.57 3.66e-12 Height; TGCT cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs7542091 0.635 rs7550733 chr1:210044968 G/A cg00989853 chr1:209979345 IRF6 0.43 4.56 0.38 1.21e-5 Monobrow; TGCT cis rs9733 0.596 rs2175615 chr1:150624101 A/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT trans rs62103177 0.810 rs62103197 chr18:77632923 G/A cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs6964587 1.000 rs10236397 chr7:91691601 C/T cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs68170813 0.559 rs2894459 chr7:106960166 C/T cg02696742 chr7:106810147 HBP1 -0.62 -4.47 -0.37 1.71e-5 Coronary artery disease; TGCT cis rs986417 0.901 rs1950310 chr14:60988526 T/A cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs9467773 1.000 rs6925895 chr6:26572165 G/T cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs854765 0.663 rs9915248 chr17:17747514 C/T cg09796270 chr17:17721594 SREBF1 -0.24 -4.52 -0.38 1.45e-5 Total body bone mineral density; TGCT cis rs9318086 0.712 rs66683041 chr13:24442090 T/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.99 11.2 0.71 1.51e-20 Myopia (pathological); TGCT cis rs2836950 0.501 rs11702505 chr21:40700614 G/T cg17971929 chr21:40555470 PSMG1 -0.51 -4.48 -0.37 1.7e-5 Menarche (age at onset); TGCT cis rs9457247 0.935 rs1187529 chr6:167376693 T/A cg23791538 chr6:167370224 RNASET2 0.49 4.63 0.38 8.93e-6 Crohn's disease; TGCT cis rs11648796 0.717 rs10682 chr16:767430 C/G cg27144592 chr16:783916 NARFL 0.39 5.56 0.45 1.56e-7 Height; TGCT cis rs7552404 1.000 rs1498315 chr1:76159225 G/A cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6582630 0.516 rs12814528 chr12:38296111 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4822044 0.617 rs13054514 chr22:42130383 A/G cg17554472 chr22:41940697 POLR3H 0.43 4.54 0.38 1.31e-5 Cannabis dependence symptom count; TGCT cis rs7552404 1.000 rs12091720 chr1:76186949 G/A cg22875332 chr1:76189707 ACADM 0.78 9.53 0.65 1.76e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9653442 0.510 rs12712068 chr2:100764439 A/G cg07810366 chr2:100720526 AFF3 -0.36 -5.29 -0.43 5.46e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg22985033 chr20:36975012 LBP 0.25 7.25 0.55 3.9e-11 Phosphorus levels; TGCT cis rs3733585 0.631 rs4697925 chr4:10124330 G/C cg11266682 chr4:10021025 SLC2A9 -0.53 -6.07 -0.48 1.43e-8 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9393777 0.778 rs13219354 chr6:27185664 T/C cg16898833 chr6:26189333 HIST1H4D 0.94 5.6 0.45 1.33e-7 Intelligence (multi-trait analysis); TGCT cis rs921968 0.541 rs4674314 chr2:219423520 A/G cg02176678 chr2:219576539 TTLL4 -0.49 -6.93 -0.53 1.99e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2688608 0.934 rs2675679 chr10:75658581 C/T cg23231163 chr10:75533350 FUT11 -0.26 -4.69 -0.39 7.01e-6 Inflammatory bowel disease; TGCT cis rs7772486 0.837 rs2474354 chr6:146323795 T/A cg05347473 chr6:146136440 FBXO30 0.5 4.83 0.4 3.94e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 1.000 rs9926296 chr16:89818089 A/G cg03388025 chr16:89894329 SPIRE2 0.4 6.27 0.49 5.45e-9 Vitiligo; TGCT cis rs7178572 1.000 rs11633054 chr15:77747276 A/G cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs3820928 1.000 rs4675120 chr2:227774888 C/T cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT trans rs6089829 0.962 rs7273930 chr20:61666017 G/A cg23505145 chr19:12996616 KLF1 0.76 7.75 0.57 2.92e-12 Prostate cancer (SNP x SNP interaction); TGCT trans rs561341 0.883 rs6505274 chr17:30344581 G/T cg20587970 chr11:113659929 NA -0.81 -9.74 -0.66 5.46e-17 Hip circumference adjusted for BMI; TGCT trans rs28735056 0.904 rs62103174 chr18:77621048 A/G cg05926928 chr17:57297772 GDPD1 0.64 6.76 0.52 4.85e-10 Schizophrenia; TGCT cis rs12950390 0.853 rs10445375 chr17:45864314 C/T cg06532163 chr17:45867833 NA -0.37 -5.96 -0.47 2.45e-8 IgG glycosylation; TGCT cis rs80264589 1 rs80264589 chr6:26927602 G/A cg16898833 chr6:26189333 HIST1H4D 1.28 6.15 0.48 9.89e-9 Lung cancer;Intelligence (multi-trait analysis); TGCT cis rs7647973 1.000 rs974495 chr3:49400482 T/C cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT cis rs61990749 0.544 rs12435761 chr14:78246077 C/G cg23188588 chr14:78226832 SNW1;C14orf178 0.64 4.5 0.37 1.54e-5 Fibroblast growth factor basic levels; TGCT cis rs9814567 1.000 rs2056603 chr3:134312749 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3733585 0.578 rs4466042 chr4:9955367 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1005277 0.505 rs200931 chr10:38128434 A/C cg25427524 chr10:38739819 LOC399744 -0.37 -7.13 -0.54 7.29e-11 Extrinsic epigenetic age acceleration; TGCT cis rs13223928 0.516 rs1872880 chr7:3148389 G/C cg19214707 chr7:3157722 NA -0.44 -6.15 -0.48 9.76e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs2997447 0.761 rs61776585 chr1:26438498 G/C cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs986417 0.818 rs8014133 chr14:61104738 A/G cg18240143 chr14:60952599 C14orf39 0.88 4.57 0.38 1.15e-5 Gut microbiota (bacterial taxa); TGCT cis rs7772486 0.536 rs9373467 chr6:145955605 C/T cg23711669 chr6:146136114 FBXO30 0.72 6.73 0.52 5.71e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs832540 0.669 rs832539 chr5:56199386 A/C cg20203395 chr5:56204925 C5orf35 -0.6 -5.43 -0.44 2.81e-7 Coronary artery disease; TGCT cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg09904177 chr6:26538194 HMGN4 0.67 6.15 0.48 9.93e-9 Intelligence (multi-trait analysis); TGCT cis rs2729354 0.768 rs2848640 chr11:57262680 A/G cg24343310 chr11:57249947 NA 0.29 4.74 0.39 5.69e-6 Blood protein levels; TGCT trans rs1814175 0.746 rs10839429 chr11:49906845 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs9393692 0.840 rs9358915 chr6:26277268 G/A cg00631329 chr6:26305371 NA -0.41 -6.09 -0.48 1.34e-8 Educational attainment; TGCT cis rs6918586 0.658 rs198838 chr6:26113340 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.69 6.43 0.5 2.44e-9 Schizophrenia; TGCT cis rs8072100 0.875 rs7208530 chr17:45544107 C/T cg08085267 chr17:45401833 C17orf57 -0.43 -4.68 -0.39 7.26e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT cis rs4819052 0.851 rs13050359 chr21:46672671 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1372520 0.577 rs1811443 chr4:90747883 G/C cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT trans rs12599106 0.839 rs3853177 chr16:34498532 A/G cg18110333 chr6:292329 DUSP22 -0.67 -7.41 -0.55 1.75e-11 Menopause (age at onset); TGCT cis rs4654899 1.000 rs7535895 chr1:21439239 T/A cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs17711722 0.528 rs73138179 chr7:65294482 G/T cg20849893 chr7:64541193 NA 0.49 5.16 0.42 9.32e-7 Calcium levels; TGCT cis rs80282103 0.867 rs13377037 chr10:1068639 C/T cg08668510 chr10:1095578 IDI1 1.08 5.21 0.42 7.5e-7 Glomerular filtration rate (creatinine); TGCT cis rs6840360 0.667 rs2709829 chr4:152355390 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs5769765 0.862 rs138870 chr22:50209737 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.36 5.5 0.44 2.1e-7 Schizophrenia; TGCT cis rs4601821 1.000 rs4601821 chr11:113250346 A/G cg14159747 chr11:113255604 NA 0.39 4.47 0.37 1.78e-5 Alcoholic chronic pancreatitis; TGCT cis rs7103648 1.000 rs2293579 chr11:47440758 G/A cg20307385 chr11:47447363 PSMC3 1.0 12.43 0.74 1.52e-23 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs11172134 0.508 rs7305179 chr12:57576567 G/C cg19258868 chr12:57585184 LRP1 -0.31 -5.93 -0.47 2.76e-8 Urate levels in overweight individuals; TGCT trans rs7819412 0.807 rs6991930 chr8:10963288 G/C cg15556689 chr8:8085844 FLJ10661 -0.73 -6.94 -0.53 1.98e-10 Triglycerides; TGCT cis rs875971 1.000 rs1182882 chr7:65562063 C/T cg11764359 chr7:65958608 NA -0.58 -4.99 -0.41 2.01e-6 Aortic root size; TGCT cis rs78487399 0.908 rs77994584 chr2:43817076 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1670533 0.872 rs10017931 chr4:1060747 G/A cg27284194 chr4:1044797 NA 0.67 5.74 0.46 6.78e-8 Recombination rate (females); TGCT cis rs11190604 1.000 rs2489035 chr10:102319395 C/T cg23241863 chr10:102295624 HIF1AN 0.69 5.21 0.42 7.75e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs10504390 0.527 rs4392943 chr8:66523799 C/A cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.29e-10 IgG glycosylation; TGCT cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg22920501 chr2:26401640 FAM59B -0.79 -6.28 -0.49 5.21e-9 Gut microbiome composition (summer); TGCT cis rs7819412 0.875 rs11250121 chr8:11060311 A/C cg27411982 chr8:10470053 RP1L1 -0.2 -4.47 -0.37 1.77e-5 Triglycerides; TGCT cis rs514406 0.621 rs1930306 chr1:53195686 C/G cg22166914 chr1:53195759 ZYG11B -0.5 -9.42 -0.65 3.19e-16 Monocyte count; TGCT cis rs74054849 0.717 rs80042126 chr1:15938108 C/A cg05660106 chr1:15850417 CASP9 0.86 4.47 0.37 1.71e-5 Alcoholic chronic pancreatitis; TGCT cis rs7772486 0.840 rs2814864 chr6:146345046 A/C cg23711669 chr6:146136114 FBXO30 0.72 6.64 0.51 8.98e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.754 rs9497401 chr6:146051271 T/C cg23711669 chr6:146136114 FBXO30 -0.95 -10.87 -0.7 9.46e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg06481639 chr22:41940642 POLR3H 0.75 6.66 0.51 8.03e-10 Vitiligo; TGCT cis rs2688608 0.592 rs10762563 chr10:75524802 C/A cg23231163 chr10:75533350 FUT11 -0.28 -4.67 -0.39 7.55e-6 Inflammatory bowel disease; TGCT cis rs752010 0.756 rs6600380 chr1:42054814 C/T cg06885757 chr1:42089581 HIVEP3 -0.24 -4.48 -0.37 1.68e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs875971 0.505 rs1167386 chr7:65513096 G/A cg00343986 chr7:65444356 GUSB -0.24 -5.53 -0.44 1.85e-7 Aortic root size; TGCT cis rs78487399 0.808 rs17039133 chr2:43694570 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg10862848 chr6:42927986 GNMT -0.38 -4.72 -0.39 6.35e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1691799 0.899 rs1168306 chr12:66738900 A/G cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs2458413 0.542 rs2514671 chr8:105364256 G/A cg04554929 chr8:105342491 NA 0.49 5.75 0.46 6.49e-8 Paget's disease; TGCT cis rs7267979 1.000 rs910997 chr20:25267301 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12291225 0.585 rs11023197 chr11:14380998 G/A cg19336497 chr11:14380999 RRAS2 -0.44 -7.14 -0.54 6.96e-11 Sense of smell; TGCT cis rs4733781 1.000 rs2114196 chr8:131225299 G/A cg16277922 chr8:131349729 ASAP1 0.45 5.65 0.45 1.03e-7 Tuberculosis; TGCT cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.59 5.24 0.43 6.7e-7 Height; TGCT cis rs7394190 0.748 rs2242254 chr10:75585307 G/A cg07699608 chr10:75541558 CHCHD1 0.8 5.52 0.44 1.86e-7 Incident atrial fibrillation; TGCT cis rs1577917 0.958 rs12193904 chr6:86452703 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.81e-7 Response to antipsychotic treatment; TGCT cis rs939658 0.626 rs11631406 chr15:79445789 C/T cg17916960 chr15:79447300 NA -0.41 -5.91 -0.47 3.1e-8 Refractive error; TGCT cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg23708337 chr7:1209742 NA 0.57 5.13 0.42 1.09e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1577917 0.771 rs2484355 chr6:86394403 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.8 -0.46 5.09e-8 Response to antipsychotic treatment; TGCT cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg00684032 chr4:1343700 KIAA1530 0.22 4.82 0.4 4.11e-6 Obesity-related traits; TGCT cis rs6426551 1.000 rs7517174 chr1:226540327 A/C cg18564989 chr1:226411057 MIXL1 -0.5 -5.04 -0.41 1.62e-6 Coronary artery disease; TGCT cis rs4733781 0.509 rs12550365 chr8:131136046 A/T cg16277922 chr8:131349729 ASAP1 0.45 6.66 0.51 7.99e-10 Tuberculosis; TGCT cis rs7772486 0.875 rs9322045 chr6:146384950 C/G cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9650657 0.645 rs56057779 chr8:10516880 G/C cg27411982 chr8:10470053 RP1L1 -0.22 -4.79 -0.4 4.62e-6 Neuroticism; TGCT cis rs11190604 0.731 rs10883480 chr10:102163821 G/T cg16005271 chr10:102321736 NA -0.43 -4.48 -0.37 1.66e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10791097 0.694 rs1893018 chr11:130756632 T/C cg12179176 chr11:130786555 SNX19 0.83 9.92 0.67 1.94e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9467773 1.000 rs9467779 chr6:26536687 A/T cg05738196 chr6:26577821 NA -0.85 -11.96 -0.73 2.09e-22 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs3820068 0.580 rs34426856 chr1:16006315 C/T cg05660106 chr1:15850417 CASP9 0.58 5.38 0.43 3.64e-7 Systolic blood pressure; TGCT cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg01448562 chr3:133502909 NA -0.26 -4.87 -0.4 3.28e-6 Iron status biomarkers; TGCT cis rs1018836 0.631 rs9987133 chr8:91470730 T/C cg16814680 chr8:91681699 NA -0.77 -7.57 -0.56 7.42e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7226408 0.847 rs115623155 chr18:34684712 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1150668 0.799 rs1736891 chr6:28187101 C/A cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.56 -0.38 1.22e-5 Pubertal anthropometrics; TGCT cis rs2370759 1.000 rs11599044 chr10:32615445 A/G cg01819863 chr10:32635814 EPC1 1.03 9.79 0.66 4.07e-17 Sexual dysfunction (female); TGCT cis rs1692580 0.807 rs4648818 chr1:2178999 C/T cg24578937 chr1:2090814 PRKCZ 0.2 4.48 0.37 1.7e-5 Coronary artery disease; TGCT cis rs1075232 1.000 rs56396205 chr15:31678385 G/A cg01030201 chr15:31746330 NA -1.1 -5.4 -0.44 3.27e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs10206020 0.921 rs72776300 chr2:1571152 A/G cg01028140 chr2:1542097 TPO -0.32 -4.99 -0.41 1.97e-6 IgG glycosylation; TGCT cis rs4808199 0.948 rs757000 chr19:19448301 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.63 4.56 0.38 1.23e-5 Nonalcoholic fatty liver disease; TGCT cis rs3849570 1.000 rs9817181 chr3:81827765 A/C cg07356753 chr3:81810745 GBE1 -0.81 -7.4 -0.55 1.81e-11 Waist circumference;Body mass index; TGCT cis rs12882406 0.602 rs4981470 chr14:23811264 C/G cg16420801 chr14:23816088 SLC22A17 -0.27 -4.47 -0.37 1.71e-5 Body mass index; TGCT cis rs6901004 0.803 rs354539 chr6:111517829 T/C cg15721981 chr6:111408429 SLC16A10 -0.51 -4.48 -0.37 1.66e-5 Blood metabolite levels; TGCT cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs11098499 0.863 rs3822192 chr4:120445720 A/C cg09307838 chr4:120376055 NA 0.68 6.47 0.5 2.02e-9 Corneal astigmatism; TGCT cis rs2017387 0.572 rs283518 chr19:50492564 C/T cg19230443 chr19:49950584 PIH1D1 -0.28 -4.62 -0.38 9.5e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs6088580 0.634 rs6088483 chr20:32984714 T/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg07061783 chr6:25882402 NA -0.58 -5.57 -0.45 1.48e-7 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg11905131 chr22:24372483 LOC391322 -0.98 -12.41 -0.74 1.79e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs5771242 0.769 rs4838865 chr22:50664612 A/G cg26607758 chr8:91997553 NA 0.78 7.88 0.58 1.42e-12 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs6076065 0.962 rs2424529 chr20:23369317 A/G cg11657817 chr20:23433608 CST11 0.28 4.62 0.38 9.4e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs1048238 0.506 rs7552077 chr1:16196759 A/G cg22431228 chr1:16359049 CLCNKA -0.22 -4.48 -0.37 1.69e-5 Systolic blood pressure; TGCT cis rs2404602 1.000 rs12594541 chr15:76834368 G/A cg22467129 chr15:76604101 ETFA -0.5 -5.63 -0.45 1.12e-7 Blood metabolite levels; TGCT cis rs4851254 0.961 rs13022707 chr2:100734946 C/A cg07810366 chr2:100720526 AFF3 -0.4 -4.48 -0.37 1.67e-5 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.731 rs1689275 chr1:76409655 T/C cg22875332 chr1:76189707 ACADM -0.67 -6.89 -0.53 2.5e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.39 -0.44 3.44e-7 Coronary artery disease; TGCT trans rs9951602 0.512 rs9946123 chr18:76654557 A/G cg02800362 chr5:177631904 HNRNPAB 1.14 12.55 0.75 7.84e-24 Obesity-related traits; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg10150615 chr22:24372951 LOC391322 0.81 9.1 0.63 1.9e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs66561647 0.634 rs7387606 chr8:128929371 A/G cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.54 0.38 1.29e-5 Hemoglobin concentration; TGCT cis rs8050907 0.744 rs9922933 chr16:4572602 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.58 4.74 0.39 5.67e-6 Obesity-related traits; TGCT cis rs11585357 0.843 rs12095095 chr1:17625832 C/G cg08277548 chr1:17600880 PADI3 -0.95 -9.58 -0.65 1.3e-16 Hair shape; TGCT cis rs933688 1.000 rs35712350 chr5:90679519 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.99 9.32 0.64 5.44e-16 Smoking behavior; TGCT cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg01448562 chr3:133502909 NA 0.35 7.38 0.55 2e-11 Iron status biomarkers; TGCT cis rs7524258 0.903 rs4908609 chr1:7292910 G/A cg04342483 chr1:7259290 CAMTA1 -0.31 -4.49 -0.37 1.6e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg25703541 chr22:24373054 LOC391322 -0.82 -8.62 -0.61 2.61e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4642101 0.824 rs3889515 chr3:12844112 G/C cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs7617773 0.780 rs71323396 chr3:48374734 T/G cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs2013441 1.000 rs2703799 chr17:20085768 G/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs6964587 0.967 rs10280620 chr7:91582183 C/G cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs295140 0.933 rs10931900 chr2:201177193 T/C cg04283868 chr2:201171347 SPATS2L 0.65 6.67 0.51 7.73e-10 QT interval; TGCT cis rs7208859 0.673 rs28588622 chr17:29245699 G/A cg18442181 chr17:29233375 C17orf42 -0.75 -4.49 -0.37 1.61e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg15659132 chr6:26577336 NA 0.84 10.39 0.68 1.39e-18 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs115317002 chr4:119722809 T/C cg21605333 chr4:119757512 SEC24D 1.72 8.99 0.63 3.52e-15 Cannabis dependence symptom count; TGCT cis rs931127 0.719 rs7949980 chr11:65445950 T/C cg17480646 chr11:65405466 SIPA1 -0.44 -5.8 -0.46 5.26e-8 Systemic lupus erythematosus; TGCT cis rs1008375 1.000 rs7659718 chr4:17638020 A/C cg10189774 chr4:17578691 LAP3 0.65 5.64 0.45 1.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4808199 0.895 rs8105094 chr19:19374061 C/T cg03709012 chr19:19516395 GATAD2A 0.8 6.04 0.48 1.66e-8 Nonalcoholic fatty liver disease; TGCT cis rs9549367 0.577 rs3024713 chr13:113813321 G/A cg18105134 chr13:113819100 PROZ -0.46 -7.31 -0.55 2.88e-11 Platelet distribution width; TGCT cis rs35306767 0.903 rs17159970 chr10:935601 T/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg20607798 chr8:58055168 NA 0.6 5.0 0.41 1.9e-6 Developmental language disorder (linguistic errors); TGCT cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg07507251 chr3:52567010 NT5DC2 0.46 6.38 0.5 3.24e-9 Bipolar disorder; TGCT cis rs9302065 1.000 rs2389236 chr13:95971477 G/A cg24476569 chr13:95954382 ABCC4 -0.44 -6.63 -0.51 9.28e-10 Blood metabolite levels; TGCT cis rs9611565 0.512 rs5996063 chr22:42168767 G/A cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs6089584 0.854 rs6061985 chr20:60622362 T/C cg06108461 chr20:60628389 TAF4 -0.69 -10.64 -0.69 3.59e-19 Body mass index; TGCT cis rs801193 1.000 rs2003301 chr7:66147656 G/C cg00343986 chr7:65444356 GUSB -0.22 -5.01 -0.41 1.84e-6 Aortic root size; TGCT cis rs7617773 0.780 rs11718350 chr3:48360992 T/G cg11946769 chr3:48343235 NME6 0.82 7.08 0.54 9.69e-11 Coronary artery disease; TGCT cis rs12136530 0.593 rs12125806 chr1:19734781 A/G cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs68170813 0.559 rs12538090 chr7:106974647 T/C cg02696742 chr7:106810147 HBP1 -0.66 -5.68 -0.45 9.27e-8 Coronary artery disease; TGCT cis rs1862618 0.671 rs2591968 chr5:56233541 A/G cg24531977 chr5:56204891 C5orf35 -0.66 -6.92 -0.53 2.12e-10 Initial pursuit acceleration; TGCT cis rs11190604 1.000 rs11190572 chr10:102232879 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4880487 0.505 rs4880778 chr10:1205810 C/G cg03183215 chr10:1252341 ADARB2 -0.24 -4.73 -0.39 5.99e-6 Migraine; TGCT cis rs3902035 0.964 rs62422258 chr6:119007427 T/G cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs2836974 0.799 rs8129303 chr21:40711959 G/A cg11644478 chr21:40555479 PSMG1 0.9 8.16 0.59 3.16e-13 Cognitive function; TGCT cis rs7917772 0.636 rs1475644 chr10:104491164 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.59 4.83 0.4 3.92e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1843834 0.539 rs2068244 chr2:225440011 A/G cg22455342 chr2:225449267 CUL3 -1.06 -10.84 -0.7 1.16e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs58235267 0.656 rs13410889 chr2:63087778 T/C cg17519650 chr2:63277830 OTX1 0.55 5.07 0.41 1.44e-6 Prostate-specific antigen levels (conditioned on lead SNPs); TGCT cis rs3733585 0.673 rs7377578 chr4:9952775 T/C cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs1814175 0.607 rs11493324 chr11:50011304 T/C cg03929089 chr4:120376271 NA -0.6 -6.94 -0.53 1.9e-10 Height; TGCT cis rs2153535 0.580 rs9379213 chr6:8474945 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6880778 0.505 rs11952844 chr5:40384295 G/C cg01087697 chr5:40835557 RPL37 0.55 4.91 0.4 2.86e-6 Inflammatory bowel disease; TGCT cis rs9549260 0.651 rs9549251 chr13:41228650 A/G cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs9473924 0.542 rs67538952 chr6:50894400 T/C cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.53 4.63 0.38 9.19e-6 Height; TGCT cis rs7089973 0.604 rs765173 chr10:116601675 C/T cg03647239 chr10:116582469 FAM160B1 0.61 5.86 0.47 3.87e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs2637266 0.967 rs2579760 chr10:78321768 A/C cg18941641 chr10:78392320 NA 0.39 4.84 0.4 3.73e-6 Pulmonary function; TGCT cis rs2075371 1.000 rs7486 chr7:133975183 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.68e-9 Mean platelet volume; TGCT cis rs4796354 0.676 rs12951137 chr17:6695697 A/G cg04115740 chr17:6690948 FBXO39 0.25 4.54 0.38 1.32e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs10089 1.000 rs6595800 chr5:127411647 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs80282103 0.867 rs7098169 chr10:1078601 G/A cg18964960 chr10:1102726 WDR37 1.13 4.43 0.37 2.01e-5 Glomerular filtration rate (creatinine); TGCT cis rs12541335 0.639 rs11779277 chr8:22200683 C/T cg26039829 chr8:22132926 PIWIL2 0.27 5.13 0.42 1.1e-6 Hypertriglyceridemia; TGCT cis rs6088580 0.567 rs6088520 chr20:33132364 A/G cg08999081 chr20:33150536 PIGU -0.27 -5.32 -0.43 4.72e-7 Glomerular filtration rate (creatinine); TGCT cis rs7698623 0.702 rs4693884 chr4:88770229 C/T cg02735620 chr4:88950514 PKD2 0.44 4.81 0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs7727544 0.740 rs419291 chr5:131633355 T/C cg24060327 chr5:131705240 SLC22A5 -0.56 -6.07 -0.48 1.45e-8 Blood metabolite levels; TGCT trans rs9990220 0.586 rs12106967 chr3:112060758 T/C cg23646235 chr19:36164513 UPK1A -0.48 -6.69 -0.51 6.93e-10 Eosinophil percentage of white cells; TGCT cis rs11098499 0.820 rs6534140 chr4:120455311 C/T cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs2228479 0.867 rs35542367 chr16:89965825 G/C cg04013166 chr16:89971882 TCF25 0.33 4.47 0.37 1.75e-5 Skin colour saturation; TGCT cis rs7617773 0.779 rs9833309 chr3:48327450 C/T cg11946769 chr3:48343235 NME6 0.74 6.34 0.49 3.97e-9 Coronary artery disease; TGCT cis rs5769765 0.624 rs2285187 chr22:50185432 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.95 -8.54 -0.61 4.11e-14 Schizophrenia; TGCT cis rs2458413 0.586 rs2669453 chr8:105368930 C/A cg04554929 chr8:105342491 NA 0.51 6.34 0.49 3.86e-9 Paget's disease; TGCT cis rs7659604 0.935 rs73844280 chr4:122664687 G/A cg19748678 chr4:122722346 EXOSC9 0.57 5.5 0.44 2.07e-7 Type 2 diabetes; TGCT cis rs7926906 0.577 rs1981424 chr11:90516272 C/T cg26138821 chr11:89956704 CHORDC1 -0.48 -4.85 -0.4 3.61e-6 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.592 rs5758427 chr22:42099688 A/G cg06634786 chr22:41940651 POLR3H 0.89 9.09 0.63 1.96e-15 Vitiligo; TGCT cis rs2692947 0.727 rs1657502 chr2:96795608 A/C cg23100626 chr2:96804247 ASTL 0.43 5.32 0.43 4.67e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT trans rs877282 0.945 rs10904555 chr10:787740 C/A cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs6089829 0.962 rs6089825 chr20:61668447 C/T cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.85e-8 Prostate cancer (SNP x SNP interaction); TGCT trans rs114540395 0.858 rs117998275 chr10:103183891 T/G cg10198749 chr1:39920707 MACF1 0.52 7.12 0.54 7.77e-11 Schizophrenia; TGCT cis rs6582630 0.537 rs11611326 chr12:38547958 C/A cg26384229 chr12:38710491 ALG10B 0.85 7.75 0.57 2.91e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs4845570 1.000 rs4845579 chr1:151770138 C/T cg07092448 chr1:151763213 TDRKH -1.13 -9.59 -0.65 1.26e-16 Coronary artery disease; TGCT cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg20607798 chr8:58055168 NA 0.49 5.76 0.46 6.31e-8 Developmental language disorder (linguistic errors); TGCT cis rs6951245 0.786 rs77943789 chr7:1140158 C/T cg18402987 chr7:1209562 NA 0.69 6.05 0.48 1.58e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12478296 0.901 rs59477854 chr2:243015490 T/C cg06360820 chr2:242988706 NA -0.59 -4.83 -0.4 3.89e-6 Obesity-related traits; TGCT cis rs3740393 0.562 rs72845847 chr10:104531606 A/G cg05855489 chr10:104503620 C10orf26 0.79 6.32 0.49 4.23e-9 Microalbuminuria; TGCT cis rs6952808 0.771 rs10275045 chr7:1920826 C/T cg22963979 chr7:1858916 MAD1L1 -0.38 -5.99 -0.47 2.13e-8 Bipolar disorder and schizophrenia; TGCT trans rs797680 0.856 rs11164876 chr1:93630510 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.78 -0.52 4.27e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9883204 1.000 rs2124500 chr3:123093530 T/C cg04890266 chr3:123102914 ADCY5 -0.36 -5.11 -0.42 1.17e-6 Birth weight; TGCT cis rs2549003 0.870 rs61175929 chr5:131821548 C/G cg21138405 chr5:131827807 IRF1 0.19 4.82 0.4 4.09e-6 Asthma (sex interaction); TGCT cis rs5750830 0.649 rs5750811 chr22:39793066 G/T cg01416388 chr22:39784598 NA 0.72 7.55 0.56 8.25e-12 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.800 rs1559858 chr4:99024075 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.55 0.56 8.37e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.867 rs4583210 chr15:43660925 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg04234412 chr22:24373322 LOC391322 -0.92 -11.41 -0.72 4.62e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs7618501 0.521 rs11712056 chr3:49914397 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.85 8.93 0.63 4.73e-15 Intelligence (multi-trait analysis); TGCT trans rs7726839 0.574 rs11134148 chr5:637107 C/T cg11887960 chr12:57824829 NA 1.14 9.28 0.64 6.87e-16 Obesity-related traits; TGCT cis rs4819052 0.765 rs2838827 chr21:46656146 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.69 6.07 0.48 1.41e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg03517284 chr6:25882590 NA -0.66 -5.8 -0.46 5.14e-8 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.818 rs437147 chr6:145875423 A/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs67311347 1.000 rs962847 chr3:40495156 A/G cg17264618 chr3:40429014 ENTPD3 -0.32 -4.45 -0.37 1.9e-5 Renal cell carcinoma; TGCT cis rs7542091 0.669 rs7540534 chr1:210044824 A/T cg21951975 chr1:209979733 IRF6 0.6 6.1 0.48 1.24e-8 Monobrow; TGCT cis rs4786125 0.665 rs6500857 chr16:6903364 C/T cg03623568 chr16:6915990 A2BP1 -0.42 -6.03 -0.48 1.72e-8 Heart rate variability traits (SDNN); TGCT cis rs11098499 0.954 rs59394118 chr4:120295551 A/G cg09307838 chr4:120376055 NA 0.66 6.46 0.5 2.15e-9 Corneal astigmatism; TGCT cis rs1215050 0.782 rs6532693 chr4:98655815 T/C cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2692947 0.644 rs1030864 chr2:96822373 A/G cg23100626 chr2:96804247 ASTL 0.47 5.57 0.45 1.52e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg11494091 chr17:61959527 GH2 0.61 14.35 0.79 4.1e-28 Prudent dietary pattern; TGCT trans rs2469997 1.000 rs2447171 chr8:120360953 C/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs7267979 1.000 rs2482931 chr20:25334445 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7714584 1.000 rs1896708 chr5:150245076 A/T cg22134413 chr5:150180641 NA 0.87 6.75 0.52 4.97e-10 Crohn's disease; TGCT cis rs9611519 0.507 rs12484525 chr22:41443877 G/C cg03806693 chr22:41940476 POLR3H -0.59 -5.48 -0.44 2.29e-7 Neuroticism; TGCT cis rs7267979 1.000 rs4815421 chr20:25386509 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9902453 0.904 rs4994353 chr17:28386280 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs950169 0.881 rs34117475 chr15:85108443 T/C cg17173187 chr15:85201210 NMB 0.48 5.02 0.41 1.75e-6 Schizophrenia; TGCT cis rs17376456 0.877 rs9314093 chr5:93333347 G/A cg25358565 chr5:93447407 FAM172A 0.97 8.5 0.61 5.11e-14 Diabetic retinopathy; TGCT cis rs7666738 0.530 rs2865992 chr4:99067181 A/T cg05340658 chr4:99064831 C4orf37 0.44 5.3 0.43 5.03e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs739496 0.579 rs9971746 chr12:112337362 A/G cg10833066 chr12:111807467 FAM109A -0.38 -5.41 -0.44 3.08e-7 Platelet count; TGCT cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg18402987 chr7:1209562 NA 0.76 6.6 0.51 1.08e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs564309 0.681 rs1150918 chr1:228608689 T/C cg22700015 chr1:228743131 NA -0.77 -4.57 -0.38 1.16e-5 Hip circumference (psychosocial stress interaction); TGCT cis rs13394619 0.775 rs10200851 chr2:11722082 C/T cg07314298 chr2:11723111 GREB1 -0.3 -5.05 -0.41 1.54e-6 Endometriosis; TGCT cis rs7666738 0.924 rs13124368 chr4:99039615 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs6913797 chr6:146413758 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6882046 0.513 rs2431391 chr5:88046590 C/T cg22951263 chr5:87985283 NA -0.55 -5.91 -0.47 3.09e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs1062177 1.000 rs2964576 chr5:151150602 T/G cg12924095 chr5:151150029 G3BP1 0.35 5.09 0.42 1.31e-6 Preschool internalizing problems; TGCT cis rs12765878 0.580 rs11191840 chr10:105634896 A/T cg11005552 chr10:105648138 OBFC1 -0.4 -6.28 -0.49 5.19e-9 Coronary artery disease; TGCT cis rs2463822 0.507 rs72919442 chr11:62028707 A/G cg06239285 chr11:62104954 ASRGL1 -0.91 -5.82 -0.46 4.64e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7312933 0.567 rs11181399 chr12:42666412 G/A cg19980929 chr12:42632907 YAF2 0.42 5.87 0.47 3.69e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6570726 0.791 rs378937 chr6:145834745 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.44 -0.37 2e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.48 -4.66 -0.39 8.07e-6 Prudent dietary pattern; TGCT cis rs7439150 1.000 rs1800787 chr4:155484015 C/T cg22130008 chr4:155548532 NA -0.47 -5.8 -0.46 5.25e-8 Fibrinogen levels; TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs9393777 0.668 rs3800318 chr6:27263641 A/T cg11262757 chr6:27280423 POM121L2 0.63 4.69 0.39 7.21e-6 Intelligence (multi-trait analysis); TGCT cis rs9400467 0.537 rs12202418 chr6:111451467 A/G cg15721981 chr6:111408429 SLC16A10 0.71 4.57 0.38 1.15e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs225245 0.755 rs226441 chr17:34033072 C/T cg05299278 chr17:33885742 SLFN14 0.21 4.53 0.38 1.37e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs7659604 1.000 rs35901586 chr4:122664757 T/A cg19748678 chr4:122722346 EXOSC9 0.57 5.5 0.44 2.07e-7 Type 2 diabetes; TGCT cis rs56235845 0.694 rs36102285 chr5:176774018 C/T cg17509989 chr5:176798049 RGS14 0.57 7.78 0.57 2.49e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg06640241 chr16:89574553 SPG7 0.77 8.86 0.62 7.12e-15 Multiple myeloma (IgH translocation); TGCT cis rs200986 1 rs200986 chr6:27824766 G/C cg18675097 chr6:28227127 NKAPL -0.35 -4.57 -0.38 1.18e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7582180 0.629 rs10202326 chr2:100950237 A/G cg14675211 chr2:100938903 LONRF2 0.53 5.16 0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.565 rs8055825 chr16:89832848 C/T cg04287289 chr16:89883240 FANCA 0.91 11.7 0.72 9.35e-22 Vitiligo; TGCT cis rs1371867 0.846 rs2919469 chr8:101233896 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.85 -0.4 3.62e-6 Atrioventricular conduction; TGCT cis rs1981331 0.609 rs59121565 chr21:48043023 A/G cg17243659 chr21:48055224 PRMT2 1.26 6.43 0.5 2.45e-9 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs73198271 0.694 rs73201840 chr8:8647067 G/T cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs77633900 0.614 rs2468120 chr15:76909975 G/A cg21673338 chr15:77095150 SCAPER -0.51 -4.82 -0.4 4.09e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs6938 0.618 rs11072514 chr15:75221865 T/A cg10253484 chr15:75165896 SCAMP2 -0.57 -5.05 -0.41 1.53e-6 Breast cancer; TGCT cis rs11785400 0.793 rs2976400 chr8:143743611 G/A cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs986417 0.818 rs761557 chr14:61077484 C/T cg07862488 chr14:60977054 SIX6 0.61 5.32 0.43 4.59e-7 Gut microbiota (bacterial taxa); TGCT cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.56 -0.51 1.33e-9 Alzheimer's disease; TGCT cis rs1903068 0.785 rs10013228 chr4:55997340 A/G cg16572876 chr4:56024045 NA 0.42 4.74 0.39 5.64e-6 Endometriosis; TGCT cis rs7267979 1.000 rs6050602 chr20:25401203 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2236918 0.622 rs1776177 chr1:242012149 C/T cg04158730 chr1:242011433 EXO1 0.49 4.5 0.37 1.54e-5 Menopause (age at onset); TGCT cis rs6484504 0.576 rs286653 chr11:31227824 C/T cg14844989 chr11:31128820 NA -0.23 -4.46 -0.37 1.83e-5 Red blood cell count; TGCT cis rs4727027 0.933 rs62505074 chr7:148834780 C/T cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs360798 0.857 rs2710636 chr2:63202997 T/C cg17519650 chr2:63277830 OTX1 0.63 4.54 0.38 1.29e-5 Coronary artery disease; TGCT cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10791323 0.604 rs2853116 chr11:133707063 A/G cg03690763 chr11:133734501 NA -0.35 -5.38 -0.43 3.58e-7 Childhood ear infection; TGCT cis rs7267979 0.740 rs2259961 chr20:25282626 T/G cg03522245 chr20:25566470 NINL 0.55 5.55 0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9916302 0.706 rs8073907 chr17:37424149 C/T cg07936489 chr17:37558343 FBXL20 -0.84 -6.23 -0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs55883249 0.957 rs16867083 chr2:9767441 C/T cg23886495 chr2:9695866 ADAM17 -0.73 -4.94 -0.41 2.52e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs915832 1.000 rs915832 chr21:43275495 C/T cg14897238 chr21:43198283 NA 0.39 4.53 0.38 1.36e-5 Response to taxane treatment (placlitaxel); TGCT cis rs3749237 0.595 rs17650792 chr3:49390250 A/G cg02487422 chr3:49467188 NICN1 0.63 6.42 0.5 2.62e-9 Resting heart rate; TGCT cis rs11249608 0.636 rs13359572 chr5:178449276 T/C cg21905437 chr5:178450457 ZNF879 0.45 4.48 0.37 1.67e-5 Pubertal anthropometrics; TGCT cis rs79419269 0.643 rs73169668 chr7:150930363 C/T cg03289901 chr7:150933506 CHPF2 0.32 4.45 0.37 1.85e-5 Immunoglobulin light chain (AL) amyloidosis; TGCT cis rs9811920 0.809 rs6806323 chr3:99722564 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.18 0.42 8.58e-7 Axial length; TGCT cis rs185694 1.000 rs846498 chr13:30900541 A/G cg07600127 chr13:30881527 KATNAL1 -0.81 -6.53 -0.51 1.53e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs6978712 0.685 rs7784284 chr7:127155188 G/A cg02908720 chr7:127292155 SND1 -0.7 -4.47 -0.37 1.71e-5 Medication adherence in chronic diseases; TGCT cis rs2228479 0.850 rs11640188 chr16:89807732 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7264396 0.676 rs6060723 chr20:34549947 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs7552404 0.731 rs1493367 chr1:76344011 C/A cg10523679 chr1:76189770 ACADM -0.83 -7.8 -0.57 2.24e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9325144 0.560 rs11183189 chr12:38683770 T/A cg26384229 chr12:38710491 ALG10B 0.64 5.77 0.46 5.98e-8 Morning vs. evening chronotype; TGCT cis rs3806843 0.576 rs246064 chr5:140324309 C/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9906944 0.933 rs12945020 chr17:47082775 G/A cg20966754 chr17:47091339 IGF2BP1 -0.43 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7833790 1.000 rs7833790 chr8:82731157 T/C cg23324259 chr8:82754387 SNX16 -0.65 -4.6 -0.38 1.04e-5 Diastolic blood pressure; TGCT cis rs11105298 0.891 rs10858906 chr12:89934474 C/T cg00757033 chr12:89920650 WDR51B 0.29 4.6 0.38 1.01e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6815814 0.950 rs114719937 chr4:38808585 G/C cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs796364 1.000 rs281785 chr2:200749566 A/G cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs7017914 0.905 rs1908033 chr8:71922799 C/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs7027203 0.576 rs4509402 chr9:96543377 C/T cg13679303 chr9:96623674 NA 0.53 7.61 0.56 6.13e-12 DNA methylation (variation); TGCT cis rs4237845 0.804 rs11172372 chr12:58286273 T/C cg02175503 chr12:58329896 NA 0.51 5.26 0.43 6.21e-7 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.710 rs4845685 chr1:154878300 C/A cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT trans rs4650994 1.000 rs12138561 chr1:178518784 G/T cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.54e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs71597109 0.957 rs2052445 chr4:102738722 A/G cg14855874 chr4:102712397 BANK1 0.42 4.43 0.37 2.01e-5 Chronic lymphocytic leukemia; TGCT cis rs4689388 0.853 rs13103357 chr4:6294544 A/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7552404 0.655 rs1146646 chr1:76265500 G/A cg03433033 chr1:76189801 ACADM 0.6 6.39 0.5 3.02e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1008375 0.966 rs2010053 chr4:17583806 A/C cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13326165 0.715 rs34908451 chr3:52385115 C/T cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs208520 0.690 rs207114 chr6:66791703 C/T cg07460842 chr6:66804631 NA -0.96 -10.02 -0.67 1.14e-17 Exhaled nitric oxide output; TGCT cis rs4819052 0.851 rs35871601 chr21:46675214 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs6089829 0.962 rs6011548 chr20:61666063 C/T cg17470723 chr8:74884337 TCEB1 0.74 6.92 0.53 2.19e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs539096 0.505 rs501861 chr1:44101440 T/A cg12908607 chr1:44402522 ARTN -0.56 -5.99 -0.47 2.08e-8 Intelligence (multi-trait analysis); TGCT cis rs9733 0.596 rs11586422 chr1:150679358 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs7100689 0.646 rs9804233 chr10:82134667 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs6570726 0.791 rs427128 chr6:145865917 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg08627397 chr16:89984028 MC1R -0.3 -4.68 -0.39 7.47e-6 Vitiligo; TGCT cis rs858239 0.570 rs6968242 chr7:23167411 T/G cg05602783 chr7:23145260 KLHL7 -0.65 -5.48 -0.44 2.32e-7 Cerebrospinal fluid biomarker levels; TGCT trans rs8073060 0.586 rs225303 chr17:33922149 A/G cg19694781 chr19:47549865 TMEM160 0.59 13.16 0.76 2.77e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs875971 1.000 rs10215948 chr7:65747786 G/A cg11764359 chr7:65958608 NA -0.61 -5.36 -0.43 3.96e-7 Aortic root size; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg01238044 chr22:24384105 GSTT1 -0.57 -5.54 -0.45 1.7e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13326165 0.760 rs13076890 chr3:52407933 T/C cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs924607 1.000 rs1697978 chr5:642829 A/G cg18765565 chr5:669397 TPPP 0.59 6.3 0.49 4.73e-9 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs12142240 0.698 rs1057534 chr1:46815880 A/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6570726 0.791 rs9390336 chr6:145896823 A/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2594989 0.565 rs7621843 chr3:11603229 T/G cg00170343 chr3:11313890 ATG7 -0.66 -5.03 -0.41 1.69e-6 Circulating chemerin levels; TGCT cis rs7772486 0.686 rs6570705 chr6:145961201 C/T cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs12477438 0.520 rs34766932 chr2:99737273 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg08280861 chr8:58055591 NA 0.39 4.56 0.38 1.2e-5 Developmental language disorder (linguistic errors); TGCT cis rs682748 0.846 rs12655526 chr5:17128613 A/G cg23987134 chr5:17158319 LOC285696 -0.21 -5.11 -0.42 1.21e-6 Hippocampal atrophy; TGCT cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg11890956 chr21:40555474 PSMG1 -0.69 -6.72 -0.52 5.77e-10 Menarche (age at onset); TGCT cis rs6988636 1.000 rs58741168 chr8:124191852 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs4919669 0.668 rs7086898 chr10:104386152 A/G cg05855489 chr10:104503620 C10orf26 0.71 4.69 0.39 7.18e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs7208859 0.673 rs9899525 chr17:29120296 T/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs797680 0.964 rs1856027 chr1:93544131 T/C cg17826107 chr1:92977322 EVI5 -0.21 -4.94 -0.41 2.51e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1949733 0.701 rs940136 chr4:8448992 G/A cg11789530 chr4:8429930 ACOX3 0.53 4.99 0.41 2e-6 Response to antineoplastic agents; TGCT cis rs9549367 1.000 rs9549367 chr13:113911532 C/G cg00898013 chr13:113819073 PROZ -0.38 -4.68 -0.39 7.39e-6 Platelet distribution width; TGCT cis rs478304 0.934 rs474483 chr11:65520060 T/G cg17480646 chr11:65405466 SIPA1 0.43 5.38 0.43 3.62e-7 Acne (severe); TGCT cis rs4803468 1.000 rs17318666 chr19:41940342 T/G cg09537434 chr19:41945824 ATP5SL 0.91 10.05 0.67 9.48e-18 Height; TGCT cis rs8177253 0.965 rs4854760 chr3:133498741 C/T cg08439880 chr3:133502540 NA 0.32 6.08 0.48 1.34e-8 Iron status biomarkers; TGCT cis rs3796352 1.000 rs13074524 chr3:52974184 A/G cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs35160687 0.901 rs34069316 chr2:86529792 T/C cg12542933 chr2:85804724 VAMP8 0.41 4.9 0.4 2.97e-6 Night sleep phenotypes; TGCT cis rs7647973 0.667 rs11721148 chr3:49646669 G/A cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs1403694 0.966 rs1656910 chr3:186438993 A/C cg12454167 chr3:186435060 KNG1 0.42 7.28 0.55 3.38e-11 Blood protein levels; TGCT cis rs2439831 1.000 rs550239 chr15:43720197 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs7223966 1.000 rs2854218 chr17:61942940 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7617773 0.817 rs6800492 chr3:48323890 G/A cg11946769 chr3:48343235 NME6 0.72 6.12 0.48 1.14e-8 Coronary artery disease; TGCT cis rs4455778 0.580 rs4529410 chr7:49125486 C/T cg26309511 chr7:48887640 NA 0.48 6.25 0.49 6.09e-9 Lung cancer in never smokers; TGCT cis rs916888 0.779 rs199528 chr17:44843136 C/T cg16228356 chr17:43848958 NA -0.26 -4.62 -0.38 9.47e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7666738 0.830 rs11931166 chr4:99054187 A/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1451375 1.000 rs1451374 chr7:50622653 G/A cg18232548 chr7:50535776 DDC 0.43 6.8 0.52 3.98e-10 Malaria; TGCT cis rs7103648 0.695 rs7933019 chr11:47509137 G/C cg20307385 chr11:47447363 PSMC3 0.87 8.49 0.61 5.4e-14 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs4665809 1.000 rs6720314 chr2:26334852 G/A cg22920501 chr2:26401640 FAM59B -0.71 -6.41 -0.5 2.81e-9 Gut microbiome composition (summer); TGCT cis rs73058052 0.597 rs11878568 chr19:50095961 T/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.93 0.47 2.83e-8 Fibrinogen levels; TGCT cis rs644799 1.000 rs474252 chr11:95619292 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.84 9.85 0.66 2.9e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12210905 1.000 rs12209393 chr6:27085073 C/T cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg03452623 chr4:187889614 NA -0.36 -5.46 -0.44 2.45e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs11118844 0.793 rs10218652 chr1:221947406 T/C cg04222084 chr1:221915650 DUSP10 -0.72 -5.05 -0.41 1.51e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs78487399 0.908 rs76765584 chr2:43808034 C/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1577917 0.958 rs16876530 chr6:86595641 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.71e-7 Response to antipsychotic treatment; TGCT cis rs1865760 0.566 rs4529296 chr6:26083135 C/G cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs2242116 0.761 rs6780601 chr3:46965856 A/G cg02527881 chr3:46936655 PTH1R -0.33 -6.09 -0.48 1.29e-8 Birth weight; TGCT cis rs908922 0.885 rs2181173 chr1:152474866 A/T cg20991723 chr1:152506922 NA -0.46 -6.3 -0.49 4.81e-9 Hair morphology; TGCT cis rs1532993 0.518 rs6822846 chr4:98636833 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.92 -0.4 2.72e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs12477438 0.520 rs4588238 chr2:99749350 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs137699 1.000 rs2049986 chr22:39756854 C/G cg05872129 chr22:39784769 NA 0.58 5.17 0.42 8.97e-7 IgG glycosylation; TGCT cis rs2933343 0.700 rs6787833 chr3:128656184 A/G cg11901034 chr3:128598214 ACAD9 -0.65 -6.08 -0.48 1.38e-8 IgG glycosylation; TGCT cis rs13177918 0.677 rs2073472 chr5:149824067 T/C cg14059543 chr5:149831962 NA -0.71 -9.34 -0.64 4.91e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1865760 0.622 rs10946807 chr6:26079638 T/C cg17042849 chr6:26104293 HIST1H4C -0.85 -7.46 -0.56 1.29e-11 Height; TGCT cis rs9549260 0.539 rs4943813 chr13:41338134 G/C cg21288729 chr13:41239152 FOXO1 0.95 9.2 0.64 1.08e-15 Red blood cell count; TGCT cis rs259282 0.605 rs66489063 chr19:33108959 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.34 0.43 4.25e-7 Schizophrenia; TGCT cis rs709400 0.663 rs10133035 chr14:103979127 C/T cg12935359 chr14:103987150 CKB -0.38 -5.7 -0.46 8.3e-8 Body mass index; TGCT cis rs7584330 0.780 rs12474519 chr2:238377012 G/A cg14458575 chr2:238380390 NA 0.5 8.08 0.59 4.96e-13 Prostate cancer; TGCT cis rs1218582 0.772 rs6656435 chr1:154876869 G/A cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs7635838 0.819 rs2454481 chr3:11535178 C/T cg00170343 chr3:11313890 ATG7 0.68 6.36 0.5 3.46e-9 HDL cholesterol; TGCT cis rs9322193 0.923 rs9800871 chr6:149965676 A/G cg13206674 chr6:150067644 NUP43 0.51 4.45 0.37 1.91e-5 Lung cancer; TGCT cis rs68170813 0.559 rs11769527 chr7:106912948 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs79349575 0.783 rs318095 chr17:46974734 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.47 -0.37 1.72e-5 Type 2 diabetes; TGCT cis rs11118844 0.793 rs12136350 chr1:221943347 C/T cg04222084 chr1:221915650 DUSP10 -0.89 -5.75 -0.46 6.42e-8 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs3008870 0.651 rs2815376 chr1:67508531 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.7 6.81 0.52 3.66e-10 Lymphocyte percentage of white cells; TGCT cis rs4722166 0.630 rs12700391 chr7:22777327 C/A cg26061582 chr7:22766209 IL6 0.57 7.36 0.55 2.27e-11 Lung cancer; TGCT cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg24829409 chr8:58192753 C8orf71 -0.58 -5.32 -0.43 4.67e-7 Developmental language disorder (linguistic errors); TGCT cis rs34034915 1 rs34034915 chr6:27720703 T/TG cg10876282 chr6:28092338 ZSCAN16 0.5 5.09 0.42 1.29e-6 Hepatitis A; TGCT cis rs5750830 0.594 rs9611166 chr22:39775268 T/C cg11247378 chr22:39784982 NA -0.64 -8.48 -0.61 5.71e-14 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg11890956 chr21:40555474 PSMG1 1.11 12.54 0.75 8.57e-24 Cognitive function; TGCT cis rs7208859 0.673 rs216409 chr17:28906269 C/T cg14008862 chr17:28927542 LRRC37B2 -0.72 -4.61 -0.38 9.83e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs473651 0.716 rs548179 chr2:239320505 G/A cg18131467 chr2:239335373 ASB1 0.97 12.97 0.76 7.62e-25 Multiple system atrophy; TGCT cis rs2204008 0.774 rs11495520 chr12:38060605 T/G cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg18402987 chr7:1209562 NA 0.78 6.54 0.51 1.46e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12497850 0.931 rs7430198 chr3:48988760 T/C cg07636037 chr3:49044803 WDR6 0.96 10.52 0.69 6.9e-19 Parkinson's disease; TGCT cis rs6674176 0.660 rs6801 chr1:44396646 C/G cg13606994 chr1:44402422 ARTN 0.49 5.4 0.44 3.22e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7615952 0.800 rs13086460 chr3:125646417 C/T cg05084668 chr3:125655381 ALG1L -0.75 -6.07 -0.48 1.41e-8 Blood pressure (smoking interaction); TGCT cis rs11190604 1.000 rs7099913 chr10:102314777 T/C cg16342193 chr10:102329863 NA -0.39 -4.95 -0.41 2.36e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg06753367 chr22:24256600 NA -0.25 -4.73 -0.39 5.98e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg10053473 chr17:62856997 LRRC37A3 -0.46 -6.76 -0.52 4.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs35934224 0.783 rs35554477 chr22:19856561 G/A cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT cis rs7267979 1.000 rs4815418 chr20:25382211 T/G cg03522245 chr20:25566470 NINL -0.64 -7.05 -0.53 1.12e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs739401 0.611 rs12284275 chr11:3024384 T/C cg25174290 chr11:3078921 CARS 0.5 4.83 0.4 4.01e-6 Longevity; TGCT cis rs9303401 0.659 rs34556735 chr17:56694447 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT trans rs62103177 0.636 rs9958792 chr18:77627876 T/C cg05926928 chr17:57297772 GDPD1 -0.93 -8.77 -0.62 1.15e-14 Opioid sensitivity; TGCT cis rs4851254 0.920 rs4850920 chr2:100757308 C/A cg23118464 chr2:100721844 AFF3 0.7 5.17 0.42 9.07e-7 Intelligence (multi-trait analysis); TGCT cis rs7412746 0.622 rs72704654 chr1:150826410 G/A cg09365446 chr1:150670422 GOLPH3L 0.35 4.98 0.41 2.11e-6 Melanoma; TGCT cis rs9650657 0.707 rs4841452 chr8:10687121 A/G cg27411982 chr8:10470053 RP1L1 -0.23 -5.08 -0.42 1.35e-6 Neuroticism; TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs3796352 1.000 rs2564926 chr3:53094730 G/A cg15956490 chr3:53032818 SFMBT1 -0.58 -6.57 -0.51 1.22e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs295140 0.535 rs6743157 chr2:201230076 C/T cg04283868 chr2:201171347 SPATS2L 0.52 4.99 0.41 2.02e-6 QT interval; TGCT cis rs9322193 0.923 rs66516768 chr6:149993135 C/T cg13206674 chr6:150067644 NUP43 0.53 4.56 0.38 1.23e-5 Lung cancer; TGCT cis rs1801251 0.778 rs778338 chr2:233740227 A/G cg25237894 chr2:233734115 C2orf82 -0.29 -5.61 -0.45 1.23e-7 Coronary artery disease; TGCT cis rs12579753 0.789 rs1343933 chr12:82123301 A/C cg21231944 chr12:82153410 PPFIA2 -0.36 -4.67 -0.39 7.86e-6 Resting heart rate; TGCT cis rs1691799 0.867 rs1027399 chr12:66760942 G/A cg16791601 chr12:66731901 HELB -0.29 -6.17 -0.48 8.9e-9 White blood cell count (basophil); TGCT cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg12311346 chr5:56204834 C5orf35 -0.66 -6.65 -0.51 8.41e-10 Initial pursuit acceleration; TGCT cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg02487422 chr3:49467188 NICN1 0.51 4.89 0.4 3.1e-6 Menarche (age at onset); TGCT cis rs9325144 0.647 rs35254764 chr12:39102928 T/C cg10518543 chr12:38710700 ALG10B -0.49 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs7681440 0.904 rs35424815 chr4:90767877 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs67385638 0.962 rs72872549 chr11:5290053 C/T cg12559170 chr11:5275217 HBG2 0.46 8.25 0.6 1.97e-13 Hemoglobin levels; TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg07092213 chr7:1199455 ZFAND2A -0.51 -5.85 -0.47 4.02e-8 Longevity;Endometriosis; TGCT cis rs228437 0.526 rs228434 chr6:134896214 A/G cg09872934 chr6:134495829 SGK1 -0.5 -4.62 -0.38 9.58e-6 Melanoma; TGCT cis rs6815814 0.851 rs11466617 chr4:38780471 T/C cg02016764 chr4:38805732 TLR1 -0.35 -5.51 -0.44 1.96e-7 Breast cancer; TGCT cis rs225245 0.755 rs8078905 chr17:34009029 T/C cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.56e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs9322193 0.923 rs9322207 chr6:149978321 G/A cg13206674 chr6:150067644 NUP43 0.51 4.47 0.37 1.75e-5 Lung cancer; TGCT cis rs9346649 0.802 rs1109191 chr6:168495750 G/A cg02770688 chr6:168491649 NA -0.31 -6.01 -0.47 1.94e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg06221963 chr1:154839813 KCNN3 -0.76 -13.39 -0.77 7.63e-26 Prostate cancer; TGCT cis rs4819052 0.851 rs10470246 chr21:46659017 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.78 0.52 4.27e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6570726 0.935 rs366308 chr6:145814532 T/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.16e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.552 rs6591361 chr11:68719284 T/C cg21862992 chr11:68658383 NA 0.46 6.24 0.49 6.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.74 -8.07 -0.59 5.16e-13 Uric acid levels; TGCT cis rs4906332 1.000 rs10459573 chr14:103925457 A/C cg26031613 chr14:104095156 KLC1 -0.53 -4.71 -0.39 6.62e-6 Coronary artery disease; TGCT cis rs6591182 0.503 rs11227241 chr11:65389890 G/C cg27068330 chr11:65405492 SIPA1 -0.81 -8.06 -0.59 5.51e-13 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs34014631 1.000 rs79515366 chr10:103582573 A/G cg22630918 chr10:102748988 C10orf2 0.43 4.83 0.4 3.98e-6 Coronary artery calcification; TGCT cis rs79057730 0.599 rs112891948 chr7:816059 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.74 5.64 0.45 1.08e-7 Initial pursuit acceleration; TGCT cis rs13191362 1.000 rs13191362 chr6:163033350 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.93 8.25 0.6 2e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1023500 0.506 rs6002625 chr22:42517689 A/G cg05082376 chr22:42548792 NA 0.22 5.42 0.44 2.99e-7 Schizophrenia; TGCT cis rs7552404 0.727 rs12093623 chr1:76256232 T/G cg22875332 chr1:76189707 ACADM 0.63 6.71 0.52 6.24e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs769267 0.930 rs10414830 chr19:19562332 C/T cg03709012 chr19:19516395 GATAD2A 0.76 6.42 0.5 2.64e-9 Tonsillectomy; TGCT cis rs9309473 0.687 rs6748040 chr2:73609928 A/G cg20560298 chr2:73613845 ALMS1 0.43 4.81 0.4 4.38e-6 Metabolite levels; TGCT trans rs9858542 0.953 rs9837341 chr3:49664767 A/G cg21659725 chr3:3221576 CRBN -0.69 -6.62 -0.51 9.63e-10 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2153535 0.580 rs4404802 chr6:8442052 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs9357506 0.935 rs4481428 chr6:46310647 A/G cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT trans rs57221529 0.709 rs72703090 chr5:598314 C/T cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Lung disease severity in cystic fibrosis; TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs4478858 0.735 rs4949384 chr1:31792141 A/G cg07478791 chr1:31886160 SERINC2 -0.47 -4.52 -0.38 1.43e-5 Alcohol dependence; TGCT trans rs3780486 0.846 rs10124479 chr9:33136233 T/G cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT trans rs8073060 0.586 rs225280 chr17:33976296 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT trans rs7618501 1.000 rs34614773 chr3:49753003 T/G cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs2236918 0.710 rs1776130 chr1:242023362 A/G cg04158730 chr1:242011433 EXO1 0.56 5.32 0.43 4.59e-7 Menopause (age at onset); TGCT cis rs9300255 0.568 rs1790090 chr12:123633424 G/A cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg22963979 chr7:1858916 MAD1L1 0.46 7.4 0.55 1.81e-11 Bipolar disorder and schizophrenia; TGCT cis rs854765 0.647 rs854769 chr17:18019011 A/G cg04398451 chr17:18023971 MYO15A 0.38 6.77 0.52 4.49e-10 Total body bone mineral density; TGCT cis rs11711311 0.826 rs13077644 chr3:113467777 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs2115630 0.875 rs8039472 chr15:85361644 A/G cg11189052 chr15:85197271 WDR73 -0.58 -5.18 -0.42 8.84e-7 P wave terminal force; TGCT cis rs588177 0.522 rs34358026 chr11:64015422 T/C cg04317338 chr11:64019027 PLCB3 0.79 6.73 0.52 5.67e-10 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2299587 0.500 rs7815785 chr8:17730338 T/C cg01800426 chr8:17659068 MTUS1 -0.53 -4.79 -0.4 4.62e-6 Economic and political preferences; TGCT cis rs7904368 0.754 rs11254231 chr10:16870246 A/G cg14835575 chr10:16859367 RSU1 0.58 5.81 0.46 4.9e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs317865 0.737 rs28516589 chr4:16234111 C/T cg04764131 chr4:16228633 TAPT1;FLJ39653 0.77 5.08 0.42 1.34e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs4727027 0.704 rs12535115 chr7:148895087 C/T cg23583168 chr7:148888333 NA -0.83 -11.12 -0.71 2.36e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1577917 0.917 rs1579886 chr6:86557191 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs2836950 0.545 rs11701805 chr21:40618683 T/C cg11644478 chr21:40555479 PSMG1 -0.55 -5.18 -0.42 8.6e-7 Menarche (age at onset); TGCT trans rs877282 0.583 rs11253424 chr10:813426 C/T cg22713356 chr15:30763199 NA 0.85 7.16 0.54 6.3e-11 Uric acid levels; TGCT cis rs7731657 0.537 rs4705850 chr5:130220358 A/G cg08523029 chr5:130500466 HINT1 -0.6 -4.96 -0.41 2.23e-6 Fasting plasma glucose; TGCT cis rs3812831 0.599 rs428636 chr13:114927133 T/C cg15513719 chr13:114904418 NA 0.38 4.69 0.39 7.03e-6 Schizophrenia; TGCT cis rs2688608 0.653 rs12775558 chr10:75570868 G/A cg04320760 chr10:75533139 FUT11 -0.36 -5.52 -0.44 1.89e-7 Inflammatory bowel disease; TGCT cis rs4654899 0.931 rs7520481 chr1:21140385 T/G cg01072550 chr1:21505969 NA 0.49 7.71 0.57 3.49e-12 Superior frontal gyrus grey matter volume; TGCT cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg05890377 chr2:74357713 NA 0.47 5.99 0.47 2.07e-8 Gestational age at birth (maternal effect); TGCT cis rs7681440 0.935 rs3756059 chr4:90757272 G/A cg14346243 chr4:90757452 SNCA -0.59 -5.73 -0.46 7.07e-8 Dementia with Lewy bodies; TGCT cis rs68170813 0.523 rs12154285 chr7:106993573 G/A cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs11722228 0.522 rs2241468 chr4:10113905 G/A cg26043149 chr18:55253948 FECH 1.17 12.23 0.74 4.71e-23 Gout;Urate levels;Serum uric acid levels; TGCT cis rs8014204 0.550 rs7152906 chr14:75125540 T/C cg06637938 chr14:75390232 RPS6KL1 0.66 5.99 0.47 2.12e-8 Caffeine consumption; TGCT cis rs2228479 0.681 rs62052184 chr16:89967217 T/C cg06558623 chr16:89946397 TCF25 0.41 4.99 0.41 1.97e-6 Skin colour saturation; TGCT cis rs7635838 0.963 rs7627171 chr3:11413429 G/C cg00170343 chr3:11313890 ATG7 0.61 5.78 0.46 5.68e-8 HDL cholesterol; TGCT cis rs7513165 0.551 rs12750834 chr1:204140784 G/A cg12731349 chr1:204159619 KISS1 0.49 4.84 0.4 3.74e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg17554472 chr22:41940697 POLR3H 0.49 5.06 0.41 1.44e-6 Vitiligo; TGCT cis rs2172802 0.570 rs2133009 chr4:62516026 T/C cg04118610 chr4:62707027 LPHN3 -0.41 -4.89 -0.4 3.07e-6 Partial epilepsies; TGCT cis rs2933343 0.700 rs1680778 chr3:128614185 A/C cg11901034 chr3:128598214 ACAD9 -0.64 -6.26 -0.49 5.85e-9 IgG glycosylation; TGCT cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg24250549 chr1:154909240 PMVK 0.62 6.28 0.49 5.29e-9 Prostate cancer; TGCT cis rs929354 0.772 rs3802123 chr7:156970641 G/A cg05182265 chr7:156933206 UBE3C -0.37 -8.2 -0.59 2.57e-13 Body mass index; TGCT cis rs2562456 0.876 rs62110163 chr19:21728822 G/A cg25650185 chr19:21324782 ZNF431 -0.64 -5.73 -0.46 7.12e-8 Pain; TGCT cis rs4253772 0.591 rs6519994 chr22:46656805 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.55 -4.46 -0.37 1.84e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs1018836 0.851 rs7004287 chr8:91620842 G/C cg16814680 chr8:91681699 NA -0.83 -8.71 -0.62 1.56e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4478858 0.735 rs11582342 chr1:31810681 A/G cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs9868809 0.505 rs56735597 chr3:48765168 A/G cg15315015 chr3:49131774 QRICH1 0.92 4.52 0.38 1.4e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7178572 0.524 rs2175941 chr15:77584498 T/C cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs3617 0.625 rs2245647 chr3:52862753 A/G cg10802521 chr3:52805072 NEK4 -0.6 -6.89 -0.53 2.46e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2439831 0.702 rs7175032 chr15:44060236 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs9297145 1.000 rs10953280 chr7:98763405 A/G cg05967295 chr7:98741636 SMURF1 -1.03 -16.21 -0.82 1.99e-32 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs904251 0.772 rs2252920 chr6:37418327 A/G cg25019722 chr6:37503610 NA -0.44 -4.99 -0.41 2.01e-6 Cognitive performance; TGCT cis rs62064224 0.554 rs9894877 chr17:30679517 T/A cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.66e-6 Schizophrenia; TGCT cis rs7044106 0.791 rs10985001 chr9:123484232 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.6 6.46 0.5 2.12e-9 Hip circumference adjusted for BMI; TGCT cis rs992157 0.687 rs10206984 chr2:219066980 C/T cg00012203 chr2:219082015 ARPC2 0.81 10.19 0.68 4.34e-18 Colorectal cancer; TGCT trans rs7615952 0.932 rs13321217 chr3:125631771 G/A cg07211511 chr3:129823064 LOC729375 -0.43 -7.22 -0.54 4.49e-11 Blood pressure (smoking interaction); TGCT cis rs1857353 1.000 rs4949851 chr1:75858519 A/G cg11838876 chr1:75668600 SLC44A5 -0.46 -4.52 -0.38 1.41e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs2228479 1.000 rs62052180 chr16:89963289 C/G cg19635926 chr16:89946313 TCF25 0.29 4.84 0.4 3.84e-6 Skin colour saturation; TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs7542091 0.704 rs9429825 chr1:210052133 C/G cg23283495 chr1:209979779 IRF6 0.55 5.42 0.44 3.02e-7 Monobrow; TGCT cis rs11249608 0.636 rs13359549 chr5:178449178 T/A cg01312482 chr5:178451176 ZNF879 -0.58 -5.77 -0.46 5.94e-8 Pubertal anthropometrics; TGCT cis rs2153535 0.580 rs1328862 chr6:8526681 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs9303401 0.659 rs34468504 chr17:56648277 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs2549003 1.000 rs17848418 chr5:131821188 C/T cg02551604 chr5:131831745 NA -0.89 -11.95 -0.73 2.33e-22 Asthma (sex interaction); TGCT cis rs17741873 0.779 rs17631000 chr10:75602500 C/T cg07699608 chr10:75541558 CHCHD1 -0.73 -5.05 -0.41 1.51e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs2153535 0.580 rs6941670 chr6:8446346 G/A cg07606381 chr6:8435919 SLC35B3 0.55 5.17 0.42 9.24e-7 Motion sickness; TGCT cis rs3784262 0.869 rs12903792 chr15:58261280 C/T cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.78 -0.57 2.39e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9653442 0.545 rs1821826 chr2:100764711 C/T cg07810366 chr2:100720526 AFF3 -0.37 -5.54 -0.45 1.75e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1008375 1.000 rs10939744 chr4:17664473 G/T cg18681998 chr4:17616180 MED28 0.94 11.11 0.71 2.49e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2456568 0.835 rs8181533 chr11:93638614 C/T cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.09e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7845219 0.506 rs12548999 chr8:95929843 C/T cg16049864 chr8:95962084 TP53INP1 -0.47 -5.12 -0.42 1.11e-6 Type 2 diabetes; TGCT cis rs7249142 0.562 rs1050544 chr19:19287901 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.34 -4.73 -0.39 5.96e-6 IgG glycosylation; TGCT cis rs12681287 0.752 rs12677470 chr8:87260559 G/A cg27223183 chr8:87520930 FAM82B -0.81 -5.66 -0.45 9.9e-8 Caudate activity during reward; TGCT cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.659 rs12351277 chr9:5061405 A/C cg02405213 chr9:5042618 JAK2 -0.73 -9.89 -0.66 2.38e-17 Pediatric autoimmune diseases; TGCT cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs58950470 0.849 rs7122657 chr11:65378028 C/T cg27068330 chr11:65405492 SIPA1 0.61 5.36 0.43 3.92e-7 Schizophrenia; TGCT cis rs3782455 1.000 rs117139141 chr12:114402939 T/G cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7044106 0.791 rs7043969 chr9:123493989 A/C cg14255062 chr9:123606675 PSMD5;LOC253039 0.2 4.74 0.39 5.66e-6 Hip circumference adjusted for BMI; TGCT cis rs1949733 1.000 rs2631758 chr4:8495304 G/A cg13073564 chr4:8508604 NA 0.5 5.52 0.44 1.91e-7 Response to antineoplastic agents; TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs7772486 0.790 rs4896852 chr6:146284621 T/C cg23711669 chr6:146136114 FBXO30 -0.88 -10.07 -0.67 8.66e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.58 5.84 0.46 4.25e-8 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.772 rs4845400 chr1:154872523 C/T cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs9527 0.615 rs3897401 chr10:104696379 T/C cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs7568458 0.870 rs6719046 chr2:85757371 G/A cg02493740 chr2:85810744 VAMP5 -0.27 -4.81 -0.4 4.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2549003 1.000 rs2070722 chr5:131824486 A/C cg02551604 chr5:131831745 NA -0.88 -12.37 -0.74 2.22e-23 Asthma (sex interaction); TGCT cis rs4372836 0.658 rs11127189 chr2:28992020 T/G cg09522027 chr2:28974177 PPP1CB -0.68 -6.93 -0.53 2e-10 Body mass index; TGCT cis rs9611565 0.625 rs2076199 chr22:41903743 G/T cg02107564 chr22:41488750 EP300 -0.55 -4.51 -0.38 1.49e-5 Vitiligo; TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg24675658 chr1:53192096 ZYG11B -0.74 -9.03 -0.63 2.84e-15 Monocyte count; TGCT cis rs7666738 0.830 rs3846445 chr4:99032939 T/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT trans rs2727020 0.796 rs7131672 chr11:49274421 A/C cg15704280 chr7:45808275 SEPT13 0.68 7.13 0.54 7.39e-11 Coronary artery disease; TGCT cis rs1215050 0.791 rs2658477 chr4:98850993 G/A cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.18e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7255045 0.742 rs10411443 chr19:12950948 C/G cg23899408 chr19:12877188 HOOK2 0.58 4.7 0.39 6.71e-6 Mean corpuscular volume; TGCT cis rs896854 0.967 rs896853 chr8:95960855 G/C cg23172400 chr8:95962367 TP53INP1 -0.4 -6.79 -0.52 4.22e-10 Type 2 diabetes; TGCT cis rs854765 0.663 rs6502618 chr17:17746741 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.7 -6.65 -0.51 8.42e-10 Total body bone mineral density; TGCT cis rs478304 0.654 rs7934036 chr11:65451020 G/T cg17480646 chr11:65405466 SIPA1 -0.63 -8.24 -0.59 2.09e-13 Acne (severe); TGCT cis rs6933660 0.745 rs6557138 chr6:151732017 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.87 -9.14 -0.63 1.48e-15 Menarche (age at onset); TGCT cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.720 rs4896837 chr6:146014168 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs611744 0.647 rs647907 chr8:109251374 T/C cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs2762353 0.808 rs1165151 chr6:25821616 T/G cg03517284 chr6:25882590 NA -0.58 -6.03 -0.48 1.76e-8 Blood metabolite levels; TGCT cis rs57221529 0.766 rs12519763 chr5:559145 C/T cg09021430 chr5:549028 NA -0.4 -5.46 -0.44 2.44e-7 Lung disease severity in cystic fibrosis; TGCT cis rs2836974 0.666 rs4818015 chr21:40675493 A/C cg17971929 chr21:40555470 PSMG1 0.73 7.23 0.54 4.31e-11 Cognitive function; TGCT cis rs17270561 0.887 rs12201170 chr6:25866247 A/G cg17042849 chr6:26104293 HIST1H4C -0.89 -5.78 -0.46 5.57e-8 Iron status biomarkers; TGCT cis rs2737273 0.849 rs2249250 chr9:35711806 G/T cg12717594 chr9:36037454 RECK 0.53 4.49 0.37 1.61e-5 Platelet distribution width; TGCT cis rs4803468 0.967 rs11083619 chr19:41913267 A/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.69 -0.69 2.72e-19 Height; TGCT cis rs7072216 0.727 rs3750603 chr10:100175536 A/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs4665809 0.549 rs72809635 chr2:26411674 G/A cg26119090 chr2:26468346 HADHA;HADHB 0.95 5.74 0.46 6.74e-8 Gut microbiome composition (summer); TGCT cis rs6429082 0.818 rs291340 chr1:235674379 C/T cg26050004 chr1:235667680 B3GALNT2 0.59 5.23 0.42 7.08e-7 Adiposity; TGCT cis rs2688608 0.592 rs10824031 chr10:75509273 C/T cg04320760 chr10:75533139 FUT11 -0.36 -5.66 -0.45 9.83e-8 Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs9905704 0.647 rs11079367 chr17:57009024 A/G cg12560992 chr17:57184187 TRIM37 0.58 4.93 0.4 2.57e-6 Testicular germ cell tumor; TGCT cis rs1552244 0.882 rs9757159 chr3:10039166 C/T cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs17376456 0.778 rs10440717 chr5:93424852 C/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs614226 0.935 rs7956998 chr12:120994932 G/A cg01236616 chr12:121019343 POP5 1.26 13.2 0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT cis rs909002 0.819 rs2292989 chr1:32135773 A/G cg11573219 chr1:32083031 HCRTR1 0.38 4.69 0.39 7.04e-6 Intelligence (multi-trait analysis); TGCT cis rs9549260 0.577 rs6563841 chr13:41239178 A/C cg21288729 chr13:41239152 FOXO1 1.01 10.63 0.69 3.76e-19 Red blood cell count; TGCT cis rs9549367 0.713 rs3024764 chr13:113824314 A/G cg09473364 chr13:112927190 NA -0.31 -4.74 -0.39 5.81e-6 Platelet distribution width; TGCT cis rs8180040 0.726 rs2061197 chr3:47001350 C/T cg27129171 chr3:47204927 SETD2 -0.73 -9.52 -0.65 1.86e-16 Colorectal cancer; TGCT cis rs11190604 1.000 rs11190597 chr10:102293676 A/T cg16342193 chr10:102329863 NA -0.41 -5.37 -0.43 3.78e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs858239 0.600 rs7341483 chr7:23127657 G/T cg05602783 chr7:23145260 KLHL7 0.6 4.99 0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9303401 0.659 rs714959 chr17:56628601 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs4455778 0.580 rs6583507 chr7:49122261 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs4906332 1.000 rs12896612 chr14:103877868 A/G cg26031613 chr14:104095156 KLC1 -0.5 -4.45 -0.37 1.89e-5 Coronary artery disease; TGCT cis rs10751667 0.666 rs7944815 chr11:959776 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT cis rs1903068 0.819 rs17711320 chr4:56000053 A/C cg01777861 chr4:56023843 NA 0.54 6.38 0.5 3.2e-9 Endometriosis; TGCT cis rs9733 0.650 rs4970923 chr1:150608300 A/G cg13175981 chr1:150552382 MCL1 0.51 5.75 0.46 6.61e-8 Tonsillectomy; TGCT cis rs2721195 0.845 rs756627 chr8:145737286 G/A cg13257436 chr8:145726034 PPP1R16A -0.32 -4.71 -0.39 6.54e-6 Age at first birth; TGCT cis rs12681288 0.862 rs34510005 chr8:1018943 T/C cg04851639 chr8:1020857 NA -0.4 -7.48 -0.56 1.21e-11 Schizophrenia; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg23034840 chr1:205782522 SLC41A1 0.55 5.02 0.41 1.73e-6 Menarche (age at onset); TGCT cis rs7809950 1.000 rs2107713 chr7:107232369 C/T cg23024343 chr7:107201750 COG5 -0.42 -6.24 -0.49 6.41e-9 Coronary artery disease; TGCT cis rs763014 0.833 rs916415 chr16:632115 G/A cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs7552404 0.727 rs2172507 chr1:76331320 A/G cg22875332 chr1:76189707 ACADM -0.59 -6.22 -0.49 6.97e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6121246 0.567 rs6058203 chr20:30198979 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs10894604 1.000 rs10894604 chr11:132641746 A/C cg16919708 chr11:133023150 OPCML -0.5 -4.6 -0.38 1.01e-5 Waist-hip ratio; TGCT cis rs56104184 0.775 rs3760785 chr19:49403178 G/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.04 -0.63 2.66e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7586879 0.796 rs36071142 chr2:25080570 C/T cg01884057 chr2:25150051 NA 0.26 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs11785400 0.963 rs9771845 chr8:143726577 C/G cg10596483 chr8:143751796 JRK 0.54 5.84 0.46 4.34e-8 Schizophrenia; TGCT cis rs13242816 1.000 rs36011826 chr7:116118336 G/A cg16553024 chr7:116138462 CAV2 -0.45 -4.81 -0.4 4.32e-6 P wave duration; TGCT cis rs1862618 0.671 rs832531 chr5:56228401 A/G cg20203395 chr5:56204925 C5orf35 -0.52 -4.8 -0.4 4.44e-6 Initial pursuit acceleration; TGCT cis rs2153535 0.580 rs9378552 chr6:8463748 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs910316 1.000 rs8017642 chr14:75590822 G/A cg23033748 chr14:75592666 NEK9 0.29 4.9 0.4 2.95e-6 Height; TGCT cis rs2455799 0.613 rs62241264 chr3:15943471 T/C cg16303742 chr3:15540471 COLQ -0.25 -4.59 -0.38 1.09e-5 Mean platelet volume; TGCT cis rs3020333 0.875 rs2982572 chr6:152010561 C/T cg22157087 chr6:152012887 ESR1 0.19 4.73 0.39 6.06e-6 Total body bone mineral density; TGCT cis rs73198271 0.628 rs11780486 chr8:8589494 C/T ch.8.214553F chr8:8189620 PRAGMIN 0.33 5.25 0.43 6.4e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7267979 0.816 rs404775 chr20:25481117 A/G cg03522245 chr20:25566470 NINL 0.56 5.79 0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs35883536 0.647 rs11166485 chr1:101048805 G/C cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs2180341 0.961 rs910720 chr6:127619070 T/C cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs763014 0.932 rs2384972 chr16:674424 G/A cg09263875 chr16:632152 PIGQ 0.31 6.91 0.53 2.25e-10 Height; TGCT cis rs7226408 0.948 rs11660227 chr18:34381823 C/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs4788570 0.538 rs16973260 chr16:71534853 A/G cg06353428 chr16:71660113 MARVELD3 1.22 7.91 0.58 1.21e-12 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs78108161 chr2:43663848 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.64 0.38 8.86e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11741688 0.557 rs10043579 chr5:178330174 C/T cg09339527 chr5:178322752 ZFP2 -0.29 -4.85 -0.4 3.57e-6 Sleep duration; TGCT cis rs61990749 0.597 rs1549119 chr14:78219812 A/T cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs6490294 0.904 rs10850003 chr12:112571169 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.52 0.44 1.93e-7 Mean platelet volume; TGCT cis rs308403 0.600 rs309367 chr4:123662211 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.73 6.85 0.52 3e-10 Blood protein levels; TGCT cis rs7572733 0.534 rs4550664 chr2:198691405 C/T cg00792783 chr2:198669748 PLCL1 0.56 5.14 0.42 1.06e-6 Dermatomyositis; TGCT cis rs7180079 0.514 rs7403751 chr15:64979291 G/C cg03791955 chr15:65024147 NA 0.29 5.58 0.45 1.41e-7 Monocyte count; TGCT cis rs10791097 0.694 rs2236717 chr11:130739887 G/T cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs736408 1.000 rs2710331 chr3:52837855 T/C cg10802521 chr3:52805072 NEK4 -0.68 -7.49 -0.56 1.11e-11 Bipolar disorder; TGCT cis rs713587 0.571 rs475868 chr2:25318059 A/G cg01884057 chr2:25150051 NA -0.26 -4.88 -0.4 3.16e-6 Body mass index in non-asthmatics; TGCT cis rs7666738 0.753 rs13120995 chr4:98972762 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs6840360 0.554 rs58751443 chr4:152709905 A/G cg22705602 chr4:152727874 NA -0.33 -5.9 -0.47 3.26e-8 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.566 rs1800702 chr6:26086463 C/G cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs6570726 0.791 rs12208812 chr6:145900924 T/G cg23711669 chr6:146136114 FBXO30 0.89 9.85 0.66 2.95e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs4144743 1.000 rs67080286 chr17:45322248 T/G cg18085866 chr17:45331354 ITGB3 -0.7 -4.67 -0.39 7.69e-6 Body mass index; TGCT cis rs910316 0.904 rs7156089 chr14:75645527 A/G cg08847533 chr14:75593920 NEK9 -0.93 -10.14 -0.67 5.65e-18 Height; TGCT cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg20637647 chr7:64974828 NA 0.93 5.2 0.42 8.11e-7 Diabetic kidney disease; TGCT cis rs1538970 0.924 rs6657284 chr1:45879088 T/C cg05343316 chr1:45956843 TESK2 0.73 5.6 0.45 1.31e-7 Platelet count; TGCT cis rs11711311 1.000 rs2712348 chr3:113460614 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.73 -6.83 -0.52 3.45e-10 IgG glycosylation; TGCT cis rs2836950 0.520 rs59916147 chr21:40634702 T/G cg11890956 chr21:40555474 PSMG1 -0.69 -6.63 -0.51 9.44e-10 Menarche (age at onset); TGCT cis rs514406 0.505 rs436363 chr1:53172163 T/C cg25767906 chr1:53392781 SCP2 -0.45 -4.98 -0.41 2.1e-6 Monocyte count; TGCT cis rs362272 0.524 rs10937924 chr4:3374898 T/C cg06533319 chr4:3265114 C4orf44 -0.27 -5.49 -0.44 2.16e-7 Serum sulfate level; TGCT cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg07061783 chr6:25882402 NA -0.45 -4.62 -0.38 9.65e-6 Blood metabolite levels; TGCT cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg25811766 chr13:21894605 NA 0.28 5.38 0.44 3.53e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs7760949 0.963 rs7761500 chr6:13917140 G/A cg27413430 chr6:13925136 RNF182 0.59 5.65 0.45 1.06e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs68170813 0.617 rs17481842 chr7:107121862 C/T cg02696742 chr7:106810147 HBP1 -0.68 -5.15 -0.42 9.83e-7 Coronary artery disease; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg23131131 chr22:24373011 LOC391322 -0.81 -8.78 -0.62 1.12e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7590720 1.000 rs7559031 chr2:216902583 A/G cg12620499 chr2:216877984 MREG 0.85 8.48 0.61 5.57e-14 Alcohol dependence; TGCT cis rs687432 0.774 rs7938062 chr11:57904766 C/T cg04811534 chr11:57115016 P2RX3 0.18 4.5 0.38 1.51e-5 Parkinson's disease; TGCT cis rs7954584 0.813 rs12827200 chr12:122451278 G/A cg21016266 chr12:122356598 WDR66 0.43 5.29 0.43 5.32e-7 Mean corpuscular volume; TGCT cis rs3741404 0.868 rs595880 chr11:64006466 T/G cg01727686 chr11:63997306 NUDT22;DNAJC4 -0.22 -4.6 -0.38 1.01e-5 Platelet count; TGCT cis rs2295359 1.000 rs736197 chr1:67607135 G/T cg03340356 chr1:67600835 NA 0.37 4.48 0.37 1.66e-5 Psoriasis; TGCT cis rs4819052 0.851 rs35871601 chr21:46675214 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9807989 0.765 rs6751977 chr2:102967430 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs10791097 0.694 rs4936123 chr11:130740967 G/A cg14779329 chr11:130786720 SNX19 0.26 4.45 0.37 1.85e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs875971 0.793 rs460678 chr7:65527200 C/G cg18876405 chr7:65276391 NA 0.32 4.86 0.4 3.49e-6 Aortic root size; TGCT cis rs2180341 0.618 rs12529077 chr6:127634244 G/T cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs2456568 0.548 rs10466335 chr11:93663820 G/C cg17595323 chr11:93583763 C11orf90 -0.42 -5.28 -0.43 5.63e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs8031584 0.678 rs4779496 chr15:31151054 A/G cg08704250 chr15:31115839 NA -0.43 -6.31 -0.49 4.47e-9 Huntington's disease progression; TGCT cis rs10940138 0.774 rs16897196 chr5:67228478 G/C ch.5.1281357F chr5:67228439 NA 0.43 5.02 0.41 1.74e-6 Menarche (age at onset); TGCT cis rs28595532 0.920 rs6818519 chr4:119787820 G/T cg21605333 chr4:119757512 SEC24D 1.44 8.24 0.6 2.03e-13 Cannabis dependence symptom count; TGCT cis rs4689388 0.750 rs10755148 chr4:6295064 A/G cg14416269 chr4:6271139 WFS1 0.37 4.72 0.39 6.17e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg02953382 chr22:24373134 LOC391322 -0.75 -7.83 -0.58 1.82e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12549025 0.559 rs721183 chr8:23385834 A/G cg00472375 chr8:23315376 ENTPD4 0.61 4.95 0.41 2.32e-6 Reticulocyte fraction of red cells; TGCT cis rs9906944 0.707 rs4794019 chr17:47107290 G/T cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.28 -0.43 5.55e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs6076065 0.963 rs6048777 chr20:23373302 C/T cg11657817 chr20:23433608 CST11 0.28 4.55 0.38 1.25e-5 Facial morphology (factor 15, philtrum width); TGCT cis rs28595532 1.000 rs115706377 chr4:119628481 G/A cg11846333 chr4:119757529 SEC24D 0.92 5.01 0.41 1.85e-6 Cannabis dependence symptom count; TGCT cis rs10507380 0.709 rs117603945 chr13:27922164 G/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs3820068 0.705 rs72643694 chr1:15860185 C/T cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs67478160 0.679 rs7156834 chr14:104211180 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.37 -0.5 3.33e-9 Schizophrenia; TGCT cis rs1953600 0.645 rs2819950 chr10:81935279 G/A cg00277334 chr10:82204260 NA 0.32 4.52 0.38 1.41e-5 Sarcoidosis; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg00024416 chr22:24240387 NA 0.37 6.42 0.5 2.58e-9 S-phenylmercapturic acid levels in smokers; TGCT cis rs7681440 0.804 rs1442135 chr4:90819093 C/T cg14346243 chr4:90757452 SNCA 0.49 4.95 0.41 2.33e-6 Dementia with Lewy bodies; TGCT cis rs644799 1.000 rs544119 chr11:95538624 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2239547 0.522 rs2581780 chr3:53058960 C/T cg11645453 chr3:52864694 ITIH4 -0.35 -5.6 -0.45 1.33e-7 Schizophrenia; TGCT cis rs2535633 0.631 rs2581819 chr3:53016552 C/A cg11645453 chr3:52864694 ITIH4 -0.27 -4.96 -0.41 2.25e-6 Body mass index; TGCT cis rs4970988 0.640 rs7524734 chr1:150655686 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Urate levels; TGCT cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6495122 0.699 rs4886410 chr15:75065644 G/C cg10253484 chr15:75165896 SCAMP2 -0.7 -6.04 -0.48 1.63e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs6867032 0.527 rs1017924 chr5:1976187 C/T cg05184729 chr5:1962311 NA -0.31 -5.25 -0.43 6.53e-7 Gut microbiome composition (winter); TGCT cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1008375 0.966 rs3775927 chr4:17599894 G/T cg16339924 chr4:17578868 LAP3 0.75 6.45 0.5 2.26e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3796352 1.000 rs3097417 chr3:53088601 C/G cg07884673 chr3:53033167 SFMBT1 -0.58 -6.29 -0.49 4.94e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7666738 0.800 rs13106995 chr4:99028790 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6088590 0.813 rs1884668 chr20:33285514 A/G cg06115741 chr20:33292138 TP53INP2 0.57 4.86 0.4 3.51e-6 Coronary artery disease; TGCT cis rs6693567 0.545 rs2133129 chr1:150355537 T/C cg09579323 chr1:150459698 TARS2 0.52 4.67 0.39 7.77e-6 Migraine; TGCT cis rs10858047 0.883 rs6681386 chr1:115183183 G/A cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs6088580 0.634 rs1205334 chr20:32930369 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.9 -0.4 2.97e-6 Glomerular filtration rate (creatinine); TGCT cis rs12220238 1.000 rs12357530 chr10:75928654 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9372498 0.536 rs9481821 chr6:118846022 A/C cg07617317 chr6:118971624 C6orf204 0.53 5.72 0.46 7.66e-8 Diastolic blood pressure; TGCT trans rs66573146 0.901 rs55659111 chr4:7012338 G/T cg07817883 chr1:32538562 TMEM39B 1.8 8.36 0.6 1.09e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs7843479 0.601 rs11780532 chr8:21838670 T/A cg17168535 chr8:21777572 XPO7 0.8 8.02 0.58 6.77e-13 Mean corpuscular volume; TGCT cis rs13191362 1.000 rs13192894 chr6:163052444 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.92 7.24 0.55 4.11e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6589563 0.737 rs56143464 chr11:116627056 G/A cg01124546 chr11:117515332 DSCAML1 -0.45 -4.85 -0.4 3.69e-6 Eosinophil counts; TGCT cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg06634786 chr22:41940651 POLR3H -0.91 -8.79 -0.62 1.02e-14 Vitiligo; TGCT cis rs11153730 0.503 rs188181 chr6:118620094 C/T cg21191810 chr6:118973309 C6orf204 0.27 4.53 0.38 1.36e-5 QT interval;Heart rate;QRS duration;QRS complex (Sokolow-Lyon); TGCT cis rs6840360 0.615 rs7669465 chr4:152609289 C/T cg17479576 chr4:152424074 FAM160A1 -0.58 -5.88 -0.47 3.63e-8 Intelligence (multi-trait analysis); TGCT cis rs12935418 0.616 rs718954 chr16:80987116 C/G cg07676361 chr16:80966860 NA -0.35 -4.7 -0.39 6.87e-6 Mean corpuscular volume; TGCT cis rs3087591 0.919 rs2953011 chr17:29412046 A/G cg24425628 chr17:29625626 OMG;NF1 0.47 7.01 0.53 1.36e-10 Hip circumference; TGCT cis rs1975974 0.511 rs56935892 chr17:21754089 A/G cg18423549 chr17:21743878 NA -0.67 -6.33 -0.49 4.06e-9 Psoriasis; TGCT cis rs3806843 0.608 rs155364 chr5:140346468 T/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.11 -0.42 1.17e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1208285 1.000 rs1208285 chr6:134158800 T/C cg01805282 chr6:133563764 EYA4 -0.44 -4.83 -0.4 4.02e-6 Infantile hypertrophic pyloric stenosis; TGCT trans rs7613875 0.580 rs6808044 chr3:50136165 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.85 -8.85 -0.62 7.57e-15 Body mass index; TGCT cis rs12693043 0.701 rs3815969 chr2:175432098 G/A cg11778734 chr2:175439522 WIPF1 -0.37 -4.67 -0.39 7.82e-6 Urate levels (BMI interaction); TGCT cis rs10931896 0.531 rs295118 chr2:201144004 C/T cg23649088 chr2:200775458 C2orf69 0.38 6.31 0.49 4.4e-9 Systolic blood pressure; TGCT cis rs709400 0.633 rs10141433 chr14:103962559 A/G cg12935359 chr14:103987150 CKB -0.36 -5.64 -0.45 1.11e-7 Body mass index; TGCT cis rs4523957 0.583 rs9907384 chr17:2045375 A/C cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1215050 0.716 rs356549 chr4:98699344 A/G cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17767294 0.708 rs79956881 chr6:28030150 T/C cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs11098499 0.863 rs10013305 chr4:120450424 G/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs2204008 0.505 rs11182550 chr12:38570061 A/T cg26384229 chr12:38710491 ALG10B 0.55 5.04 0.41 1.58e-6 Bladder cancer; TGCT cis rs67460515 0.892 rs34016896 chr3:160992864 C/T cg03342759 chr3:160939853 NMD3 -0.51 -5.42 -0.44 2.98e-7 Parkinson's disease; TGCT cis rs739496 0.527 rs12427012 chr12:112343374 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs1215050 0.740 rs783929 chr4:98972495 T/A cg05340658 chr4:99064831 C4orf37 -0.43 -5.27 -0.43 5.8e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4077515 0.935 rs3812565 chr9:139272502 T/C cg13741927 chr9:139327495 INPP5E -0.2 -4.51 -0.38 1.48e-5 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs7439150 1.000 rs2227403 chr4:155486646 T/C cg22130008 chr4:155548532 NA -0.46 -5.77 -0.46 6.08e-8 Fibrinogen levels; TGCT trans rs6089829 0.962 rs6122344 chr20:61661738 C/T cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs6977660 0.714 rs10231980 chr7:19789383 C/G cg07541023 chr7:19748670 TWISTNB 0.85 4.84 0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs9611565 0.512 rs6519289 chr22:42170432 A/C cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs4665809 1.000 rs6749855 chr2:26255263 A/G cg25036284 chr2:26402008 FAM59B -0.54 -4.68 -0.39 7.3e-6 Gut microbiome composition (summer); TGCT cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7565124 1.000 rs67305930 chr2:20258070 G/C cg00462460 chr2:20212509 MATN3 -0.43 -4.67 -0.39 7.65e-6 Major depressive disorder; TGCT cis rs950169 0.580 rs1061737 chr15:85183790 G/C cg12863693 chr15:85201151 NMB 0.46 5.56 0.45 1.6e-7 Schizophrenia; TGCT cis rs10507380 0.824 rs74918771 chr13:27921717 T/G cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg03264133 chr6:25882463 NA -0.64 -6.02 -0.48 1.86e-8 Intelligence (multi-trait analysis); TGCT cis rs111803315 1.000 rs112819780 chr14:60001564 A/G cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs8180040 1.000 rs295428 chr3:47359262 G/T cg27129171 chr3:47204927 SETD2 0.7 8.88 0.62 6.43e-15 Colorectal cancer; TGCT cis rs600231 0.706 rs3782091 chr11:65336483 G/T cg21890820 chr11:65308645 LTBP3 -0.37 -4.9 -0.4 2.91e-6 Bone mineral density; TGCT trans rs9329221 1.000 rs9329221 chr8:10240202 G/T cg15556689 chr8:8085844 FLJ10661 0.71 6.69 0.51 6.87e-10 Neuroticism; TGCT cis rs7523050 0.643 rs76218180 chr1:109404131 T/A cg08274380 chr1:109419600 GPSM2 1.31 6.12 0.48 1.15e-8 Fat distribution (HIV); TGCT cis rs3733585 0.683 rs6449140 chr4:9936437 G/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.61 -0.56 5.87e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10423674 0.526 rs34482977 chr19:18824038 C/G cg14292368 chr19:18793705 CRTC1 -0.53 -4.89 -0.4 3.1e-6 Menarche (age at onset); TGCT cis rs2832191 0.791 rs2832178 chr21:30479858 T/G cg24692254 chr21:30365293 RNF160 -0.94 -10.58 -0.69 4.82e-19 Dental caries; TGCT cis rs10256972 0.967 rs1881122 chr7:1040946 A/T cg00431813 chr7:1051703 C7orf50 -0.2 -4.44 -0.37 1.99e-5 Longevity;Endometriosis; TGCT cis rs17534004 1.000 rs17599764 chr13:31469580 G/A cg13251181 chr13:31481184 C13orf33 0.37 4.6 0.38 1.04e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs12711979 0.528 rs1823860 chr2:3867013 A/G cg17052675 chr2:3827356 NA -0.27 -4.44 -0.37 1.97e-5 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs4478858 0.746 rs7520468 chr1:31688812 G/A cg00250761 chr1:31883323 NA 0.29 4.78 0.39 4.9e-6 Alcohol dependence; TGCT cis rs2842992 0.872 rs1570318 chr6:160111473 C/T cg11366901 chr6:160182831 ACAT2 0.94 6.18 0.49 8.48e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs11190604 0.513 rs2495730 chr10:102361277 T/C cg16342193 chr10:102329863 NA -0.46 -5.15 -0.42 1.02e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11711311 0.911 rs3773681 chr3:113523901 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs67311347 1.000 rs7631893 chr3:40440869 C/T cg17264618 chr3:40429014 ENTPD3 0.3 4.44 0.37 1.97e-5 Renal cell carcinoma; TGCT cis rs13256369 0.853 rs13256216 chr8:8577883 C/T cg18904891 chr8:8559673 CLDN23 0.64 5.62 0.45 1.21e-7 Obesity-related traits; TGCT cis rs7267979 0.903 rs6115109 chr20:25239667 G/A cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs864745 0.902 rs12531540 chr7:28162674 C/T cg23620719 chr7:28220237 JAZF1 -0.5 -4.47 -0.37 1.77e-5 Crohn's disease;Type 2 diabetes; TGCT cis rs617219 0.737 rs1275103 chr5:78448105 C/G cg23514016 chr5:78407564 BHMT 0.34 5.26 0.43 6.16e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1942 0.837 rs12440045 chr15:41782684 A/C cg18705301 chr15:41695430 NDUFAF1 -0.49 -6.38 -0.5 3.2e-9 Eosinophil percentage of granulocytes; TGCT cis rs1215050 0.755 rs783958 chr4:98893836 A/T cg17366294 chr4:99064904 C4orf37 -0.53 -5.69 -0.45 8.67e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17345786 0.861 rs11707689 chr3:101086475 A/G cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 1.000 rs6804473 chr3:10060425 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs669446 0.561 rs628342 chr1:44090736 C/T cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs4699052 0.963 rs4698890 chr4:104181878 T/C cg16532752 chr4:104119610 CENPE -0.55 -4.97 -0.41 2.19e-6 Testicular germ cell tumor; TGCT cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg03188948 chr7:1209495 NA 0.47 6.37 0.5 3.42e-9 Longevity;Endometriosis; TGCT cis rs2549003 0.966 rs2706386 chr5:131832687 C/T cg00255919 chr5:131827918 IRF1 -0.22 -5.24 -0.43 6.67e-7 Asthma (sex interaction); TGCT cis rs886126 0.950 rs916682 chr12:111699146 A/G cg10833066 chr12:111807467 FAM109A 0.34 5.8 0.46 5.28e-8 Coronary heart disease; TGCT cis rs7917772 0.636 rs2863718 chr10:104519631 G/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.57 -4.62 -0.38 9.3e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7193541 0.595 rs4476202 chr16:74709940 T/C cg01733217 chr16:74700730 RFWD3 0.87 9.66 0.66 8.44e-17 Multiple myeloma; TGCT cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg13012494 chr21:47604986 C21orf56 -0.39 -4.66 -0.39 7.88e-6 Testicular germ cell tumor; TGCT cis rs1552244 0.572 rs113406084 chr3:10170190 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs9916302 0.904 rs4795384 chr17:37716771 C/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.72 -0.39 6.35e-6 Glomerular filtration rate (creatinine); TGCT cis rs6725041 0.792 rs4638732 chr2:213090070 A/C cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs79387448 0.626 rs80277428 chr2:103080056 G/A cg09003973 chr2:102972529 NA 1.36 9.34 0.64 4.94e-16 Gut microbiota (bacterial taxa); TGCT cis rs7027203 0.828 rs10122041 chr9:96615517 A/G cg14598338 chr9:96623480 NA -0.61 -9.54 -0.65 1.68e-16 DNA methylation (variation); TGCT cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs7949030 0.695 rs11231161 chr11:62378221 A/G cg13298116 chr11:62369859 EML3;MTA2 0.65 9.85 0.66 2.86e-17 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3902354 1 rs3902354 chr1:109819296 C/A cg00908766 chr1:109817496 CELSR2 0.46 4.56 0.38 1.23e-5 Cholesterol, total; TGCT trans rs4332037 0.539 rs11764780 chr7:2020904 G/C cg25206134 chr2:45395956 NA 0.97 7.33 0.55 2.6e-11 Bipolar disorder; TGCT cis rs6456156 0.846 rs7774396 chr6:167519786 G/A cg07741184 chr6:167504864 NA 0.22 4.44 0.37 2e-5 Primary biliary cholangitis; TGCT cis rs28595532 0.920 rs115994240 chr4:119744622 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg20607798 chr8:58055168 NA 0.61 5.06 0.41 1.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs17376456 0.877 rs10059230 chr5:93450347 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs10464366 0.544 rs34866559 chr7:39166071 G/A cg18850127 chr7:39170497 POU6F2 0.33 7.16 0.54 6.13e-11 IgG glycosylation; TGCT cis rs6964587 1.000 rs6944591 chr7:91642714 T/C cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs12142240 0.698 rs6684274 chr1:46810842 A/G cg14993813 chr1:46806288 NSUN4 0.58 4.78 0.39 4.79e-6 Menopause (age at onset); TGCT cis rs9467773 0.967 rs9467775 chr6:26513435 G/A cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs6558530 0.666 rs28376731 chr8:1696252 C/A cg09410841 chr8:1729607 CLN8 0.68 6.01 0.48 1.89e-8 Systolic blood pressure; TGCT trans rs7618501 0.699 rs11130224 chr3:49936910 T/A cg21665057 chr3:196295764 WDR53;FBXO45 0.87 9.3 0.64 6.15e-16 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg20203395 chr5:56204925 C5orf35 -0.58 -4.97 -0.41 2.19e-6 Initial pursuit acceleration; TGCT cis rs56235845 0.694 rs11738681 chr5:176761535 A/G cg17509989 chr5:176798049 RGS14 0.54 7.46 0.56 1.28e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs2153535 0.580 rs969421 chr6:8451949 A/C cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs1799949 0.929 rs799905 chr17:41277187 G/C cg05368731 chr17:41323189 NBR1 1.02 11.43 0.72 4.07e-21 Menopause (age at onset); TGCT cis rs7216064 1.000 rs7221651 chr17:65832390 A/G cg12091567 chr17:66097778 LOC651250 0.87 6.62 0.51 9.79e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs3803170 0.513 rs4572196 chr12:111831993 A/G cg10833066 chr12:111807467 FAM109A 0.33 5.17 0.42 9.22e-7 Mean corpuscular hemoglobin; TGCT cis rs6952808 0.636 rs6964522 chr7:1953523 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -5.94 -0.47 2.68e-8 Bipolar disorder and schizophrenia; TGCT cis rs644799 0.582 rs1727149 chr11:95497171 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.7 -7.7 -0.57 3.71e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12220238 1.000 rs11000925 chr10:75972601 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1153858 1.000 rs1145074 chr15:45703824 T/A cg14582100 chr15:45693742 SPATA5L1 0.49 6.0 0.47 2.04e-8 Homoarginine levels; TGCT cis rs780096 0.565 rs8179252 chr2:27746832 A/C cg02592271 chr2:27665507 KRTCAP3 -0.4 -4.53 -0.38 1.38e-5 Total body bone mineral density; TGCT cis rs9634489 0.502 rs2011392 chr13:97099975 T/C cg11411106 chr13:97107445 HS6ST3 -0.25 -4.44 -0.37 1.96e-5 Body mass index; TGCT cis rs12478296 0.792 rs6738361 chr2:243014257 C/T cg06360820 chr2:242988706 NA -0.83 -5.68 -0.45 9.2e-8 Obesity-related traits; TGCT cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs60843830 0.964 rs17713568 chr2:242132 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.69 6.48 0.5 1.96e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs16958440 0.867 rs76922914 chr18:44688454 T/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs7666738 0.830 rs2865979 chr4:99027137 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4809627 1 rs4809627 chr20:45757655 C/T cg27589058 chr20:45804311 EYA2 -0.3 -7.08 -0.54 9.38e-11 Type 2 diabetes; TGCT cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg15691649 chr6:25882328 NA -0.51 -6.33 -0.49 4.02e-9 Uric acid levels; TGCT cis rs9300255 0.537 rs1727334 chr12:123714236 A/G cg00376283 chr12:123451042 ABCB9 0.67 5.26 0.43 6.13e-7 Neutrophil percentage of white cells; TGCT cis rs25645 0.830 rs4072639 chr17:38189049 G/A cg17467752 chr17:38218738 THRA -0.56 -5.06 -0.41 1.46e-6 Myeloid white cell count; TGCT cis rs17152411 0.895 rs61872120 chr10:126583588 T/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs17197710 0.608 rs12573962 chr11:47305660 G/C cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2072499 0.750 rs55910626 chr1:156159909 C/G cg24450063 chr1:156163899 SLC25A44 1.11 10.16 0.67 5.03e-18 Testicular germ cell tumor; TGCT cis rs7397814 0.558 rs4764447 chr12:9579109 C/T cg27502298 chr12:9555721 NA 0.54 8.6 0.61 2.9e-14 IgG glycosylation; TGCT cis rs9916302 0.861 rs632202 chr17:37453294 C/A cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs644799 1.000 rs1944074 chr11:95511445 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.53 0.61 4.41e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs308403 0.568 rs1512975 chr4:123657342 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.71 6.62 0.51 9.74e-10 Blood protein levels; TGCT cis rs7020830 0.898 rs308492 chr9:37298020 C/T cg14294708 chr9:37120828 ZCCHC7 1.18 15.56 0.81 6.32e-31 Schizophrenia; TGCT cis rs9814567 1.000 rs1880377 chr3:134270468 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7937682 0.883 rs12366001 chr11:111433916 A/G cg09085632 chr11:111637200 PPP2R1B 0.99 9.52 0.65 1.82e-16 Primary sclerosing cholangitis; TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg24675658 chr1:53192096 ZYG11B -0.75 -8.92 -0.63 5.02e-15 Monocyte count; TGCT cis rs13191362 0.935 rs73023493 chr6:162952769 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.67 5.16 0.42 9.64e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10791323 0.569 rs10736608 chr11:133740048 C/T cg03690763 chr11:133734501 NA -0.28 -4.78 -0.39 4.96e-6 Childhood ear infection; TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg15383120 chr6:291909 DUSP22 -0.68 -7.03 -0.53 1.21e-10 Menopause (age at onset); TGCT cis rs9393692 0.905 rs9358919 chr6:26287862 C/T cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT cis rs1008375 0.966 rs11722132 chr4:17697217 T/C cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.836 rs8129355 chr21:40579869 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.51 0.65 1.95e-16 Cognitive function; TGCT cis rs4665809 0.590 rs13019536 chr2:26526978 C/A cg25036284 chr2:26402008 FAM59B -0.69 -4.95 -0.41 2.39e-6 Gut microbiome composition (summer); TGCT cis rs514406 0.584 rs12095247 chr1:53193796 A/C cg04995860 chr1:53192072 ZYG11B 0.4 4.49 0.37 1.6e-5 Monocyte count; TGCT cis rs12136530 0.714 rs34553579 chr1:19779378 A/C cg18923740 chr1:19971790 NBL1 0.37 4.53 0.38 1.34e-5 Lead levels in blood; TGCT cis rs921968 0.541 rs12617603 chr2:219369288 A/G cg02176678 chr2:219576539 TTLL4 -0.48 -6.84 -0.52 3.21e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs4665809 0.618 rs7579199 chr2:26266496 G/A cg25036284 chr2:26402008 FAM59B -0.56 -4.85 -0.4 3.62e-6 Gut microbiome composition (summer); TGCT cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg09222892 chr1:25734099 RHCE -0.43 -7.11 -0.54 7.99e-11 Erythrocyte sedimentation rate; TGCT cis rs7829975 0.846 rs6601724 chr8:8544872 C/T cg15556689 chr8:8085844 FLJ10661 -0.68 -6.14 -0.48 1e-8 Mood instability; TGCT cis rs73110464 0.609 rs6580923 chr12:53358352 A/G cg16329197 chr12:53359506 NA -0.56 -7.89 -0.58 1.32e-12 Cancer (pleiotropy); TGCT cis rs4285028 0.747 rs9850439 chr3:121393075 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs875971 0.929 rs4122249 chr7:65920936 T/C cg18876405 chr7:65276391 NA 0.31 4.67 0.39 7.78e-6 Aortic root size; TGCT cis rs66573146 0.808 rs56268690 chr4:6923887 C/T cg00135399 chr4:7783873 AFAP1 0.42 4.54 0.38 1.3e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs79349575 0.715 rs62075844 chr17:47002389 G/A cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs7959452 0.570 rs10878964 chr12:69720691 T/G cg14784868 chr12:69753453 YEATS4 0.67 6.96 0.53 1.77e-10 Blood protein levels; TGCT cis rs694739 0.628 rs11606081 chr11:64137875 T/C cg23796481 chr11:64053134 BAD;GPR137 0.64 6.62 0.51 9.49e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs8013055 0.846 rs8003942 chr14:105971670 A/G cg19700328 chr14:106028568 NA -0.53 -5.91 -0.47 3.03e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9787249 0.915 rs6664570 chr1:40206298 G/A cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs67311347 1.000 rs9835219 chr3:40424093 C/T cg13683864 chr3:40499215 RPL14 -1.11 -11.7 -0.72 9.11e-22 Renal cell carcinoma; TGCT cis rs72945132 0.769 rs3781644 chr11:70190375 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg17747265 chr1:1875780 NA -0.43 -8.09 -0.59 4.53e-13 Body mass index; TGCT cis rs40363 0.951 rs250632 chr16:3523047 C/T cg22508957 chr16:3507546 NAT15 0.56 5.41 0.44 3.11e-7 Tuberculosis; TGCT trans rs1973993 0.669 rs510552 chr1:96891671 A/G cg10631902 chr5:14652156 NA 0.4 10.92 0.7 7.19e-20 Weight; TGCT cis rs13191362 0.507 rs2849511 chr6:163139050 C/G cg06582575 chr6:163149167 PACRG;PARK2 -0.6 -5.69 -0.45 8.72e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs5750830 0.620 rs1007337 chr22:39781585 C/T cg11247378 chr22:39784982 NA -0.73 -9.73 -0.66 5.72e-17 Intelligence (multi-trait analysis); TGCT trans rs2727020 0.521 rs7107178 chr11:49526668 G/A cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Coronary artery disease; TGCT cis rs1218582 0.772 rs6686873 chr1:154913404 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.19 -0.54 5.48e-11 Prostate cancer; TGCT cis rs7100689 0.599 rs7077847 chr10:82134952 A/G cg01528321 chr10:82214614 TSPAN14 0.83 7.87 0.58 1.5e-12 Post bronchodilator FEV1; TGCT cis rs2224391 0.628 rs2753230 chr6:5248538 C/G cg09085698 chr6:5261316 LYRM4;FARS2 0.96 6.05 0.48 1.61e-8 Height; TGCT cis rs12477438 0.765 rs6749059 chr2:99591021 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -5.89 -0.47 3.39e-8 Chronic sinus infection; TGCT cis rs13217239 0.646 rs10946898 chr6:27003884 T/C cg02458000 chr6:26745757 NA 0.5 4.61 0.38 1e-5 Schizophrenia; TGCT cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -4.98 -0.41 2.11e-6 Coronary artery disease; TGCT cis rs854765 0.547 rs6502632 chr17:17913057 A/G cg04398451 chr17:18023971 MYO15A -0.32 -5.12 -0.42 1.15e-6 Total body bone mineral density; TGCT cis rs2072499 0.898 rs2736609 chr1:156202640 C/T cg06970220 chr1:156163860 SLC25A44 0.71 5.87 0.47 3.81e-8 Testicular germ cell tumor; TGCT cis rs9916302 0.904 rs620686 chr17:37453617 A/G cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs7818688 0.697 rs11783985 chr8:95979886 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg20607798 chr8:58055168 NA 0.56 4.7 0.39 6.67e-6 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.01 0.48 1.9e-8 Bipolar disorder; TGCT cis rs4478858 0.684 rs17440445 chr1:31722562 C/T cg07478791 chr1:31886160 SERINC2 0.47 4.51 0.38 1.47e-5 Alcohol dependence; TGCT cis rs2692947 0.537 rs11685849 chr2:96243804 C/A cg14612417 chr2:95688557 NA 0.37 4.68 0.39 7.34e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg17971929 chr21:40555470 PSMG1 0.98 9.47 0.65 2.42e-16 Cognitive function; TGCT cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg11502198 chr6:26597334 ABT1 0.55 4.89 0.4 3.05e-6 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.537 rs28680519 chr12:38502946 C/T cg26384229 chr12:38710491 ALG10B 0.78 7.47 0.56 1.27e-11 Bladder cancer; TGCT cis rs7226408 0.857 rs55804703 chr18:34452703 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT trans rs8073060 0.586 rs188959 chr17:34021307 C/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2836974 0.897 rs13047678 chr21:40708853 C/T cg11890956 chr21:40555474 PSMG1 1.06 9.91 0.66 2.1e-17 Cognitive function; TGCT cis rs9796 0.674 rs6492978 chr15:41317702 T/C cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.33 -0.43 4.57e-7 Menopause (age at onset); TGCT cis rs2692947 0.644 rs2969491 chr2:96794982 C/T cg23100626 chr2:96804247 ASTL 0.47 5.61 0.45 1.28e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs228437 0.526 rs228435 chr6:134896528 C/T cg09872934 chr6:134495829 SGK1 0.51 4.62 0.38 9.39e-6 Melanoma; TGCT cis rs2721195 0.816 rs4925826 chr8:145706276 G/A cg15320075 chr8:145703422 NA 0.73 7.48 0.56 1.18e-11 Age at first birth; TGCT cis rs4319547 1.000 rs6489071 chr12:123025576 C/G cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.47 -0.44 2.42e-7 Body mass index; TGCT cis rs1008375 1.000 rs3846357 chr4:17635887 A/T cg18681998 chr4:17616180 MED28 1.01 11.55 0.72 2.15e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10832963 0.594 rs1550869 chr11:18613498 G/T cg20219074 chr11:18656078 SPTY2D1 0.71 6.33 0.49 4.09e-9 Breast cancer; TGCT cis rs35306767 0.715 rs1250891 chr10:1040159 G/C cg26597838 chr10:835615 NA 0.62 6.86 0.52 2.84e-10 Eosinophil percentage of granulocytes; TGCT cis rs2742417 0.603 rs2742456 chr3:45767176 C/T cg04837898 chr3:45731254 SACM1L -0.66 -6.96 -0.53 1.77e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs916888 0.610 rs142167 chr17:44795234 C/T cg17911788 chr17:44343683 NA 0.48 5.64 0.45 1.11e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3749237 0.595 rs4855859 chr3:49526300 C/T cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs7044106 0.762 rs3903886 chr9:123383646 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.55 -6.06 -0.48 1.49e-8 Hip circumference adjusted for BMI; TGCT cis rs6570726 0.620 rs12201226 chr6:145913419 A/T cg23711669 chr6:146136114 FBXO30 0.7 6.45 0.5 2.23e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs367615 0.501 rs447849 chr5:108951190 A/C cg17395555 chr5:108820864 NA -0.25 -4.74 -0.39 5.86e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2153535 0.580 rs6929206 chr6:8447961 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs7647973 1.000 rs11719762 chr3:49409002 G/C cg05785598 chr3:49045655 WDR6 0.39 4.65 0.39 8.28e-6 Menarche (age at onset); TGCT cis rs6840360 0.870 rs1372978 chr4:152456180 A/G cg17479576 chr4:152424074 FAM160A1 -0.57 -6.34 -0.49 3.85e-9 Intelligence (multi-trait analysis); TGCT cis rs360798 0.553 rs7562734 chr2:63047973 G/C cg17519650 chr2:63277830 OTX1 -0.58 -4.83 -0.4 3.93e-6 Coronary artery disease; TGCT cis rs4372836 1.000 rs7598876 chr2:28974466 T/C cg09522027 chr2:28974177 PPP1CB -0.59 -5.15 -0.42 1e-6 Body mass index; TGCT cis rs9372253 1.000 rs2235989 chr6:110714584 A/T cg19196401 chr6:110721138 DDO -0.49 -7.08 -0.54 9.26e-11 Platelet distribution width; TGCT cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.42 4.54 0.38 1.3e-5 Menopause (age at onset); TGCT trans rs57221529 0.766 rs4245972 chr5:578572 A/G cg11887960 chr12:57824829 NA 1.1 9.44 0.65 2.89e-16 Lung disease severity in cystic fibrosis; TGCT cis rs801193 0.591 rs721717 chr7:66130292 G/T cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT trans rs4650994 0.623 rs35854525 chr1:178618604 C/T cg05059571 chr16:84539110 KIAA1609 0.41 7.11 0.54 8.28e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs1215050 0.765 rs471500 chr4:98714820 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs919433 0.713 rs6719483 chr2:198472886 A/G cg00792783 chr2:198669748 PLCL1 0.49 4.61 0.38 9.95e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs11203032 0.831 rs9651495 chr10:90932381 G/A cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs295140 0.605 rs296818 chr2:201176944 C/T cg04283868 chr2:201171347 SPATS2L -0.47 -4.47 -0.37 1.72e-5 QT interval; TGCT cis rs7296418 0.961 rs4148862 chr12:123568619 A/C cg00376283 chr12:123451042 ABCB9 0.82 7.08 0.54 9.57e-11 Platelet count; TGCT cis rs10504229 1.000 rs111915672 chr8:58191665 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -5.33 -0.43 4.56e-7 Developmental language disorder (linguistic errors); TGCT cis rs1218582 0.772 rs1109815 chr1:154909268 A/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.22 -0.54 4.53e-11 Prostate cancer; TGCT cis rs2797160 1.000 rs1739354 chr6:126017808 G/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT trans rs931812 1.000 rs4734494 chr8:101917721 T/C cg20993868 chr7:22813445 NA 0.36 8.02 0.58 6.78e-13 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs174601 0.864 rs174545 chr11:61569306 C/G cg01500311 chr11:61656094 FADS3 -0.33 -5.6 -0.45 1.3e-7 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs7937682 0.575 rs10789851 chr11:111750955 G/C cg09085632 chr11:111637200 PPP2R1B 0.88 8.5 0.61 5.19e-14 Primary sclerosing cholangitis; TGCT cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs739401 0.611 rs10833048 chr11:3020040 A/G cg05729581 chr11:3078854 CARS -0.54 -4.87 -0.4 3.33e-6 Longevity; TGCT cis rs9733 0.628 rs72700895 chr1:150626029 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs9322193 0.923 rs4354168 chr6:150017778 C/T cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs7017914 0.935 rs35564237 chr8:71600474 G/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs9914988 0.943 rs4262997 chr17:27129562 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs185694 0.779 rs628483 chr13:30895462 C/T cg07600127 chr13:30881527 KATNAL1 -0.75 -6.12 -0.48 1.11e-8 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs7633770 0.769 rs3796371 chr3:46667224 C/T cg11219411 chr3:46661640 NA 0.33 4.69 0.39 6.99e-6 Coronary artery disease; TGCT cis rs2688608 0.560 rs10128354 chr10:75470045 T/C cg15838173 chr10:75533400 FUT11 -0.31 -5.01 -0.41 1.81e-6 Inflammatory bowel disease; TGCT cis rs4665809 0.878 rs6720312 chr2:26364934 A/G cg22920501 chr2:26401640 FAM59B 0.73 6.12 0.48 1.12e-8 Gut microbiome composition (summer); TGCT cis rs77669868 0.929 rs3782007 chr11:114066438 A/G cg01914181 chr11:114070210 ZBTB16 -0.33 -6.31 -0.49 4.52e-9 Monocyte percentage of white cells; TGCT cis rs6866344 0.697 rs72812613 chr5:178135257 G/A cg10224037 chr5:178157518 ZNF354A 0.94 8.08 0.59 4.77e-13 Neutrophil percentage of white cells; TGCT cis rs35883536 0.525 rs2647321 chr1:101032006 T/G cg06223162 chr1:101003688 GPR88 0.42 7.85 0.58 1.67e-12 Monocyte count; TGCT cis rs8141529 0.732 rs6005881 chr22:29183133 A/G cg02153584 chr22:29168773 CCDC117 0.75 6.44 0.5 2.33e-9 Lymphocyte counts; TGCT cis rs6088590 0.965 rs13040449 chr20:33358901 T/A cg06115741 chr20:33292138 TP53INP2 0.67 5.6 0.45 1.34e-7 Coronary artery disease; TGCT cis rs7412746 0.658 rs72704682 chr1:150897677 A/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs617219 0.671 rs2591388 chr5:78557241 A/G cg05890484 chr5:78407552 BHMT 0.36 4.77 0.39 5.06e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9457247 0.967 rs1794694 chr6:167404751 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9325144 0.600 rs10880934 chr12:38730455 C/T cg10518543 chr12:38710700 ALG10B -0.49 -4.44 -0.37 1.99e-5 Morning vs. evening chronotype; TGCT cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg10047753 chr17:41438598 NA 0.96 9.65 0.65 9.13e-17 Menopause (age at onset); TGCT cis rs9399135 0.660 rs4646868 chr6:135271946 A/G cg24558204 chr6:135376177 HBS1L 0.5 5.39 0.44 3.37e-7 Red blood cell count; TGCT cis rs3026101 0.624 rs1058398 chr17:5288760 C/T cg25236894 chr17:5323110 RPAIN;NUP88 -0.48 -4.76 -0.39 5.33e-6 Body mass index; TGCT cis rs1403694 0.966 rs9869244 chr3:186437554 A/T cg12454167 chr3:186435060 KNG1 0.43 7.53 0.56 9.3e-12 Blood protein levels; TGCT cis rs2549003 1.000 rs2549002 chr5:131829578 C/A cg00255919 chr5:131827918 IRF1 -0.2 -4.76 -0.39 5.22e-6 Asthma (sex interaction); TGCT cis rs12682352 0.650 rs13265731 chr8:8673320 T/C cg15556689 chr8:8085844 FLJ10661 0.59 5.08 0.41 1.35e-6 Neuroticism; TGCT cis rs6840360 1.000 rs6833368 chr4:152603177 C/T cg17479576 chr4:152424074 FAM160A1 0.51 5.4 0.44 3.24e-7 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg06640241 chr16:89574553 SPG7 0.66 6.47 0.5 2.04e-9 Multiple myeloma (IgH translocation); TGCT cis rs6940638 0.688 rs2022272 chr6:27103580 A/G cg26531700 chr6:26746687 NA -0.62 -5.63 -0.45 1.15e-7 Intelligence (multi-trait analysis); TGCT cis rs4273100 0.688 rs4924980 chr17:19204863 T/C cg01534423 chr17:18965556 NA -0.79 -7.15 -0.54 6.62e-11 Schizophrenia; TGCT cis rs600231 0.665 rs12790095 chr11:65326086 T/G cg13974409 chr11:65292307 SCYL1 0.5 4.76 0.39 5.27e-6 Bone mineral density; TGCT cis rs6088580 0.634 rs6059824 chr20:33014543 T/C cg06115741 chr20:33292138 TP53INP2 0.53 4.67 0.39 7.67e-6 Glomerular filtration rate (creatinine); TGCT cis rs9993613 0.841 rs11731563 chr4:73489191 T/C cg15102770 chr4:73434591 ADAMTS3 0.5 4.62 0.38 9.46e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs8077889 0.871 rs7212648 chr17:41917962 A/C cg25876840 chr17:41920477 NA 0.24 4.53 0.38 1.36e-5 Triglycerides; TGCT cis rs350251 0.833 rs350272 chr16:12234773 A/C cg01574788 chr16:12184133 SNX29 -0.36 -4.79 -0.4 4.68e-6 Intelligence (multi-trait analysis); TGCT cis rs2485376 0.842 rs11191283 chr10:104163569 G/A cg26089160 chr10:104170217 PSD 0.51 5.03 0.41 1.68e-6 QT interval; TGCT cis rs611744 0.647 rs2859813 chr8:109263497 G/A cg21045802 chr8:109455806 TTC35 0.7 7.05 0.54 1.07e-10 Dupuytren's disease; TGCT cis rs60843830 1.000 rs2126129 chr2:212548 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.63 5.28 0.43 5.63e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9914544 0.564 rs4334348 chr17:18787004 G/T cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs3902035 0.964 rs62423961 chr6:119008401 T/C cg07617317 chr6:118971624 C6orf204 0.43 5.0 0.41 1.95e-6 QT interval; TGCT cis rs526231 0.819 rs26233 chr5:102596816 G/T cg05225461 chr5:102596755 C5orf30 0.22 4.49 0.37 1.64e-5 Primary biliary cholangitis; TGCT trans rs208520 1.000 rs12209225 chr6:66996443 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.84 7.59 0.56 6.69e-12 Exhaled nitric oxide output; TGCT cis rs12681287 0.604 rs13279589 chr8:87477723 C/T cg27223183 chr8:87520930 FAM82B -0.9 -6.49 -0.5 1.83e-9 Caudate activity during reward; TGCT cis rs3812049 0.737 rs790155 chr5:127498380 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.57 5.18 0.42 8.76e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs752010 0.523 rs943376 chr1:42122117 A/G cg06885757 chr1:42089581 HIVEP3 0.28 5.06 0.41 1.47e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs6540559 1.000 rs1044516 chr1:209959614 G/T cg21951975 chr1:209979733 IRF6 0.68 5.83 0.46 4.59e-8 Cleft lip with or without cleft palate; TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg27535305 chr1:53392650 SCP2 -0.24 -4.73 -0.39 5.98e-6 Monocyte count; TGCT cis rs36051895 0.658 rs7030260 chr9:5008070 C/A cg02405213 chr9:5042618 JAK2 -0.79 -11.27 -0.71 1.03e-20 Pediatric autoimmune diseases; TGCT cis rs7959452 0.868 rs12812860 chr12:69746671 T/C cg11871910 chr12:69753446 YEATS4 0.76 8.31 0.6 1.44e-13 Blood protein levels; TGCT cis rs12421382 0.507 rs2186673 chr11:109285519 G/A cg16359550 chr11:109292809 C11orf87 0.75 7.97 0.58 8.93e-13 Schizophrenia; TGCT cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs4455778 0.538 rs67216951 chr7:49088028 C/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs17102423 0.964 rs11623603 chr14:65602287 T/A cg11161011 chr14:65562177 MAX -0.47 -6.26 -0.49 5.62e-9 Obesity-related traits; TGCT cis rs76878669 0.561 rs1039594 chr11:66131149 C/T cg18002602 chr11:66138449 SLC29A2 0.54 6.71 0.52 6.1e-10 Educational attainment (years of education); TGCT cis rs12575642 0.660 rs58632573 chr11:63896299 C/T cg04317338 chr11:64019027 PLCB3 0.75 6.19 0.49 8.06e-9 Attention deficit hyperactivity disorder; TGCT cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg18305652 chr10:134549665 INPP5A 0.34 5.75 0.46 6.52e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg18252515 chr7:66147081 NA 1.2 7.33 0.55 2.56e-11 Diabetic kidney disease; TGCT cis rs6582630 0.638 rs10880620 chr12:38517467 A/G cg26384229 chr12:38710491 ALG10B -0.55 -4.89 -0.4 3.05e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6088590 0.561 rs6059934 chr20:33178324 G/T cg06115741 chr20:33292138 TP53INP2 0.54 4.72 0.39 6.32e-6 Coronary artery disease; TGCT cis rs10927875 0.557 rs1572381 chr1:16344494 G/A cg21385522 chr1:16154831 NA 0.47 4.85 0.4 3.57e-6 Dilated cardiomyopathy; TGCT cis rs9326248 0.813 rs588534 chr11:117068504 A/G cg16524733 chr11:117070046 TAGLN 0.34 4.5 0.37 1.52e-5 Blood protein levels; TGCT cis rs9527 0.571 rs12219246 chr10:104613355 A/G cg15744005 chr10:104629667 AS3MT -0.5 -6.39 -0.5 3.12e-9 Arsenic metabolism; TGCT cis rs10193935 0.901 rs10175378 chr2:42456267 A/C cg27598129 chr2:42591480 NA -0.39 -5.13 -0.42 1.07e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs244731 0.959 rs918459 chr5:176669030 C/T cg16006841 chr5:176797999 RGS14 -0.55 -7.36 -0.55 2.22e-11 Urate levels in lean individuals; TGCT cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg03303774 chr4:1407052 NA -0.31 -4.93 -0.4 2.6e-6 Obesity-related traits; TGCT cis rs13108904 0.934 rs13124383 chr4:1299986 C/T cg13395646 chr4:1353034 KIAA1530 -0.46 -5.84 -0.46 4.32e-8 Obesity-related traits; TGCT cis rs2191566 0.639 rs7257749 chr19:44548666 G/A cg03039196 chr19:44506973 ZNF230 0.53 4.47 0.37 1.78e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs55692411 0.517 rs13095697 chr3:50136463 G/A cg14019146 chr3:50243930 SLC38A3 -0.21 -4.58 -0.38 1.11e-5 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.779 rs6060763 chr20:30282223 A/G cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7666738 0.861 rs28829607 chr4:98964325 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg08439880 chr3:133502540 NA -0.28 -5.13 -0.42 1.11e-6 Iron status biomarkers; TGCT cis rs617219 0.574 rs3930426 chr5:78597535 C/T cg09550809 chr5:78407562 BHMT -0.34 -4.58 -0.38 1.11e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs600550 0.889 rs1365247 chr11:60027309 C/T cg18570331 chr11:60101691 MS4A6E 0.5 4.44 0.37 1.93e-5 Lipoprotein-associated phospholipase A2 activity and mass; TGCT cis rs11792861 0.816 rs2275637 chr9:111696043 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 5.0 0.41 1.88e-6 Menarche (age at onset); TGCT cis rs11585357 0.947 rs72646795 chr1:17612120 C/T cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs1075232 1.000 rs12439239 chr15:31651718 G/A cg01030201 chr15:31746330 NA -1.01 -5.25 -0.43 6.38e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs2387326 1.000 rs12252465 chr10:129932395 G/A cg03458096 chr10:129105057 DOCK1 -0.3 -4.67 -0.39 7.78e-6 Select biomarker traits; TGCT cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg20887711 chr4:1340912 KIAA1530 -0.99 -9.17 -0.64 1.27e-15 Longevity; TGCT cis rs7904368 0.806 rs6602161 chr10:16862280 A/G cg14835575 chr10:16859367 RSU1 0.68 7.26 0.55 3.79e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs13394619 0.622 rs7571803 chr2:11744573 G/A cg07314298 chr2:11723111 GREB1 0.28 4.82 0.4 4.04e-6 Endometriosis; TGCT cis rs11578119 1.000 rs66639118 chr1:170510613 G/T cg09767346 chr1:170501363 GORAB 0.65 5.17 0.42 9.21e-7 Male-pattern baldness; TGCT cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs1894292 0.527 rs11733262 chr4:74357851 A/G cg05868023 chr4:75230803 EREG 0.53 4.59 0.38 1.08e-5 Prostate cancer; TGCT cis rs3096299 0.967 rs28689480 chr16:89460093 T/C cg02187348 chr16:89574699 SPG7 0.48 4.61 0.38 9.87e-6 Multiple myeloma (IgH translocation); TGCT cis rs7043114 0.525 rs10116241 chr9:95240546 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.39 -0.44 3.36e-7 Height; TGCT cis rs17221829 0.965 rs10830365 chr11:89459065 G/A cg02982614 chr11:89391479 FOLH1B -0.27 -4.75 -0.39 5.63e-6 Anxiety in major depressive disorder; TGCT cis rs6484504 0.576 rs208088 chr11:31192686 T/C cg26647111 chr11:31128758 NA -0.34 -4.63 -0.38 9.09e-6 Red blood cell count; TGCT cis rs2288884 1.000 rs56808319 chr19:52577874 A/T cg13540795 chr19:52551618 ZNF432 -0.59 -5.0 -0.41 1.89e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs9486719 0.857 rs6568392 chr6:96861476 G/T cg18709589 chr6:96969512 KIAA0776 0.7 6.19 0.49 7.97e-9 Migraine;Coronary artery disease; TGCT cis rs7666738 0.753 rs11097607 chr4:99011640 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2486288 0.656 rs8039540 chr15:45551842 C/G cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs10788575 0.805 rs12569998 chr10:89674157 A/C cg15103050 chr10:90582504 ANKRD22 0.35 4.72 0.39 6.23e-6 Type 2 diabetes; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg23131131 chr22:24373011 LOC391322 -0.8 -8.69 -0.62 1.78e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs875971 0.895 rs778700 chr7:65866450 C/T cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs910187 0.596 rs12329631 chr20:45794427 C/T cg27589058 chr20:45804311 EYA2 -0.36 -6.84 -0.52 3.18e-10 Migraine; TGCT cis rs597539 0.652 rs668576 chr11:68668208 A/G cg06112835 chr11:68658793 MRPL21 0.47 8.3 0.6 1.48e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3791556 1.000 rs2411429 chr2:240113928 A/G cg03281426 chr2:240109471 HDAC4 0.28 4.46 0.37 1.82e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs67073037 0.955 rs11695230 chr2:29130140 G/C cg09522027 chr2:28974177 PPP1CB 0.63 4.97 0.41 2.17e-6 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs1153858 0.848 rs9806699 chr15:45740392 G/A cg14582100 chr15:45693742 SPATA5L1 0.41 4.69 0.39 7.18e-6 Homoarginine levels; TGCT cis rs7845219 0.555 rs1129152 chr8:95888307 C/T cg09323728 chr8:95962352 TP53INP1 -0.48 -5.55 -0.45 1.69e-7 Type 2 diabetes; TGCT cis rs78456975 0.574 rs13412980 chr2:1545231 C/A cg12573674 chr2:1569213 NA -0.5 -4.89 -0.4 3.04e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs739496 0.579 rs12307192 chr12:112290346 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9291683 0.588 rs2240724 chr4:10021290 G/C cg00071950 chr4:10020882 SLC2A9 0.7 9.52 0.65 1.86e-16 Bone mineral density; TGCT cis rs5769765 0.955 rs6520066 chr22:50294988 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.41 6.2 0.49 7.76e-9 Schizophrenia; TGCT cis rs9527 0.622 rs12779263 chr10:104886533 G/T cg15744005 chr10:104629667 AS3MT -0.44 -4.97 -0.41 2.21e-6 Arsenic metabolism; TGCT cis rs2486012 0.850 rs3124746 chr1:44320934 G/C cg12908607 chr1:44402522 ARTN -0.72 -5.68 -0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.712 rs7755167 chr6:88338752 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs8177253 1.000 rs6762719 chr3:133480817 A/G cg08439880 chr3:133502540 NA -0.31 -5.91 -0.47 3.08e-8 Iron status biomarkers; TGCT cis rs210138 1.000 rs210137 chr6:33542478 C/T cg24505687 chr6:33548425 BAK1 0.51 5.72 0.46 7.67e-8 Testicular germ cell tumor; TGCT cis rs2243480 1.000 rs35820085 chr7:65442758 C/T cg07424592 chr7:64974309 NA 1.36 7.93 0.58 1.1e-12 Diabetic kidney disease; TGCT cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg03264133 chr6:25882463 NA 0.51 4.71 0.39 6.45e-6 Intelligence (multi-trait analysis); TGCT cis rs9952991 1.000 rs9952991 chr18:12780464 G/A cg09945482 chr18:12777974 NA 0.48 4.52 0.38 1.43e-5 Inflammatory skin disease; TGCT cis rs911263 0.961 rs10131490 chr14:68743307 A/G cg18825221 chr14:68749962 RAD51L1 -0.27 -5.16 -0.42 9.38e-7 Primary biliary cholangitis; TGCT cis rs28595532 0.764 rs116302502 chr4:119748848 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7582180 0.764 rs11689439 chr2:100925399 T/C cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs853679 0.546 rs200950 chr6:27835772 A/G cg10876282 chr6:28092338 ZSCAN16 0.75 4.45 0.37 1.88e-5 Depression; TGCT cis rs77106637 0.929 rs1059000 chr11:72504972 G/C cg03713592 chr11:72463424 ARAP1 0.95 6.2 0.49 7.69e-9 Type 2 diabetes; TGCT cis rs7819412 0.838 rs4840544 chr8:10960572 C/T cg03192020 chr8:11204681 TDH -0.52 -4.69 -0.39 7.18e-6 Triglycerides; TGCT cis rs1552244 1.000 rs722509 chr3:10102377 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg24675658 chr1:53192096 ZYG11B 0.74 8.68 0.61 1.87e-14 Monocyte count; TGCT cis rs2204008 0.538 rs61931093 chr12:38242911 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs10779751 1.000 rs11121711 chr1:11317661 A/T cg08854313 chr1:11322531 MTOR 0.99 10.58 0.69 4.78e-19 Body mass index; TGCT cis rs739496 0.615 rs12579287 chr12:112090814 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.22 0.42 7.28e-7 Platelet count; TGCT cis rs138229 0.506 rs9628282 chr22:50534952 G/T cg08875078 chr22:50639485 SELO 0.56 4.73 0.39 6.03e-6 Behavioural disinhibition (generation interaction); TGCT cis rs2243480 1.000 rs1979823 chr7:65704613 G/A cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs7027203 0.576 rs4424329 chr9:96560806 G/C cg13679303 chr9:96623674 NA 0.53 7.61 0.56 6.13e-12 DNA methylation (variation); TGCT cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg01238044 chr22:24384105 GSTT1 -0.51 -4.9 -0.4 2.95e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2115630 0.645 rs2292463 chr15:85175750 A/G cg12863693 chr15:85201151 NMB -0.4 -5.23 -0.43 6.91e-7 P wave terminal force; TGCT cis rs2235642 0.717 rs9937922 chr16:1658154 C/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.27 -4.56 -0.38 1.22e-5 Coronary artery disease; TGCT cis rs3960554 0.709 rs73138006 chr7:75769990 T/C cg17325771 chr7:75508891 RHBDD2 -0.58 -4.83 -0.4 3.91e-6 Eotaxin levels; TGCT cis rs651907 0.535 rs13084113 chr3:101534039 C/G cg12386194 chr3:101231763 SENP7 0.45 4.45 0.37 1.87e-5 Colorectal cancer; TGCT cis rs9399135 0.967 rs9399129 chr6:135285148 C/A cg24558204 chr6:135376177 HBS1L 0.48 4.75 0.39 5.48e-6 Red blood cell count; TGCT cis rs7020830 0.898 rs308495 chr9:37277603 G/T cg14294708 chr9:37120828 ZCCHC7 1.16 15.74 0.82 2.4e-31 Schizophrenia; TGCT cis rs4862750 0.872 rs6830426 chr4:187897270 T/A cg10295955 chr4:187884368 NA -1.02 -15.6 -0.81 5.02e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs2114426 chr4:98933130 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs916888 0.531 rs183211 chr17:44788310 G/A cg10053473 chr17:62856997 LRRC37A3 -0.4 -6.81 -0.52 3.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs826838 1.000 rs11168676 chr12:38977304 A/G cg26384229 chr12:38710491 ALG10B 1.03 10.33 0.68 1.97e-18 Heart rate; TGCT cis rs7666738 0.606 rs28481322 chr4:99086638 T/C cg05340658 chr4:99064831 C4orf37 0.44 4.8 0.4 4.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs669446 0.527 rs72883034 chr1:44112379 T/C cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs476633 0.691 rs28735224 chr15:41537539 C/T cg18705301 chr15:41695430 NDUFAF1 -0.57 -7.34 -0.55 2.47e-11 Glomerular filtration rate (creatinine); TGCT cis rs60871478 0.898 rs35928069 chr7:823067 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.47 4.58 0.38 1.13e-5 Cerebrospinal P-tau181p levels; TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs6089829 0.962 rs2872543 chr20:61665017 G/A cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs6429082 0.689 rs10802803 chr1:235709610 A/G cg26050004 chr1:235667680 B3GALNT2 -0.54 -4.67 -0.39 7.62e-6 Adiposity; TGCT cis rs250677 0.524 rs250665 chr5:148454394 A/C cg18129178 chr5:148520854 ABLIM3 -0.36 -5.32 -0.43 4.66e-7 Breast cancer; TGCT cis rs2464469 0.654 rs4646570 chr15:58343146 G/C cg12031962 chr15:58353849 ALDH1A2 -0.4 -5.88 -0.47 3.57e-8 Barrett's esophagus or Esophageal adenocarcinoma; TGCT cis rs1552244 0.608 rs9837460 chr3:10049922 G/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg06374610 chr10:50328992 NA -0.83 -6.79 -0.52 4.09e-10 Follicular lymphoma; TGCT cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg05785598 chr3:49045655 WDR6 -0.37 -5.01 -0.41 1.87e-6 Menarche (age at onset); TGCT cis rs9486719 0.857 rs4346856 chr6:96880270 C/T cg18709589 chr6:96969512 KIAA0776 0.76 6.58 0.51 1.19e-9 Migraine;Coronary artery disease; TGCT cis rs9341808 0.754 rs10733162 chr6:81023389 G/A cg08355045 chr6:80787529 NA 0.26 4.46 0.37 1.79e-5 Sitting height ratio; TGCT cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg02353165 chr6:42928485 GNMT 0.97 9.86 0.66 2.8e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs3125734 0.633 rs6479792 chr10:63983264 T/G cg09941381 chr10:64027924 RTKN2 -0.36 -5.53 -0.44 1.83e-7 Rheumatoid arthritis; TGCT cis rs9902453 0.817 rs55974138 chr17:28215546 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 7.07 0.54 9.76e-11 Coffee consumption (cups per day); TGCT cis rs1018836 0.847 rs4735226 chr8:91569238 T/A cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs694419 0.602 rs7226431 chr18:60176204 A/C cg13506219 chr18:60193840 ZCCHC2 -0.55 -4.93 -0.4 2.58e-6 Serum albumin level; TGCT cis rs7267979 0.833 rs6138556 chr20:25243310 C/T cg14121845 chr20:25566513 NINL 0.49 5.44 0.44 2.73e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9517302 0.578 rs2274054 chr13:99098470 C/T cg22223119 chr13:99095684 FARP1 -0.55 -5.99 -0.47 2.16e-8 Obesity-related traits; TGCT cis rs17401966 0.627 rs35859381 chr1:10466040 G/A cg19773385 chr1:10388646 KIF1B -0.22 -5.17 -0.42 9.17e-7 Hepatocellular carcinoma; TGCT cis rs5769765 0.955 rs61136468 chr22:50312679 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.49 0.44 2.16e-7 Schizophrenia; TGCT cis rs4886920 0.563 rs4420498 chr15:78079425 T/C cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.36e-6 Neuroticism; TGCT cis rs7572733 0.515 rs1518368 chr2:198839145 G/A cg00792783 chr2:198669748 PLCL1 0.57 5.1 0.42 1.24e-6 Dermatomyositis; TGCT cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg16414030 chr3:133502952 NA -0.65 -10.6 -0.69 4.35e-19 Iron status biomarkers; TGCT cis rs317689 0.581 rs160829 chr12:69769538 G/C cg14784868 chr12:69753453 YEATS4 0.64 5.72 0.46 7.3900000000000007e-08 Response to diuretic therapy; TGCT cis rs36051895 0.623 rs2146040 chr9:5260039 C/G cg02405213 chr9:5042618 JAK2 0.72 9.78 0.66 4.22e-17 Pediatric autoimmune diseases; TGCT cis rs59107033 0.643 rs9841543 chr3:123118315 T/C cg04890266 chr3:123102914 ADCY5 -0.38 -5.96 -0.47 2.4e-8 Lymphocyte counts; TGCT trans rs3780486 0.801 rs56687083 chr9:33132134 A/G cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs185694 0.947 rs595451 chr13:30896848 T/C cg07600127 chr13:30881527 KATNAL1 -0.82 -6.64 -0.51 8.92e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs9486715 0.838 rs4839840 chr6:96941149 T/C cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg06697600 chr4:7070879 GRPEL1 -0.44 -4.51 -0.38 1.49e-5 Monocyte percentage of white cells; TGCT cis rs2657888 0.965 rs2694909 chr12:56934928 T/C cg23932658 chr12:57637574 STAC3 0.48 4.57 0.38 1.18e-5 Adiponectin levels; TGCT cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT cis rs6089829 0.855 rs6090205 chr20:61665269 A/G cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9457247 0.905 rs453184 chr6:167387404 A/C cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs7208859 0.623 rs77544470 chr17:28934550 C/A cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1887596 0.663 rs2776437 chr13:27245466 A/G cg01312412 chr13:27282625 NA 0.28 5.07 0.41 1.41e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs6430585 0.527 rs76622824 chr2:136411879 A/G cg07169764 chr2:136633963 MCM6 0.97 8.24 0.59 2.09e-13 Corneal structure; TGCT cis rs7255045 0.742 rs7251196 chr19:12950863 C/T cg23899408 chr19:12877188 HOOK2 -0.58 -4.73 -0.39 5.98e-6 Mean corpuscular volume; TGCT cis rs425277 0.916 rs414777 chr1:2101687 G/A cg03732007 chr1:2071316 PRKCZ 0.26 5.29 0.43 5.41e-7 Height; TGCT cis rs2980436 1 rs2980436 chr8:8092025 A/G cg15462221 chr8:8086144 FLJ10661 0.56 5.45 0.44 2.66e-7 Schizophrenia; TGCT cis rs1532993 0.518 rs3907814 chr4:98586758 C/A cg05340658 chr4:99064831 C4orf37 -0.42 -5.02 -0.41 1.75e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg27588902 chr6:42928151 GNMT -0.56 -6.93 -0.53 2.08e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs3806843 0.576 rs246062 chr5:140324580 T/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6570726 0.599 rs9376951 chr6:145898911 C/T cg05347473 chr6:146136440 FBXO30 0.62 5.7 0.46 8.22e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs4919694 0.901 rs79331374 chr10:104882913 G/A cg04362960 chr10:104952993 NT5C2 1.08 7.22 0.54 4.53e-11 Arsenic metabolism; TGCT cis rs6429082 0.791 rs61836205 chr1:235638753 C/G cg26050004 chr1:235667680 B3GALNT2 0.57 4.95 0.41 2.41e-6 Adiposity; TGCT cis rs62064224 0.614 rs4795700 chr17:30763794 A/G cg18200150 chr17:30822561 MYO1D 0.44 5.28 0.43 5.61e-7 Schizophrenia; TGCT cis rs8056742 0.642 rs11149705 chr16:85026261 T/G cg00229868 chr16:85520891 NA 0.37 4.67 0.39 7.7e-6 Amyotrophic lateral sclerosis; TGCT cis rs9300255 0.739 rs12824957 chr12:123750228 T/C cg00376283 chr12:123451042 ABCB9 -0.73 -5.04 -0.41 1.6e-6 Neutrophil percentage of white cells; TGCT cis rs72781680 0.716 rs2712065 chr2:23973603 C/T cg08917208 chr2:24149416 ATAD2B -0.79 -4.94 -0.41 2.51e-6 Lymphocyte counts; TGCT cis rs9818758 0.607 rs10049462 chr3:49309684 C/T cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1635 0.826 rs742107 chr6:28290714 A/C cg15743358 chr6:28303923 ZNF323 -1.27 -6.2 -0.49 7.86e-9 Schizophrenia; TGCT cis rs4242434 0.646 rs6988593 chr8:22527440 A/G cg03733263 chr8:22462867 KIAA1967 -1.02 -14.95 -0.8 1.55e-29 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg10802521 chr3:52805072 NEK4 -0.73 -9.23 -0.64 9.18e-16 Bipolar disorder; TGCT cis rs28785552 0.536 rs7246050 chr19:53248632 T/C cg22067481 chr19:53234126 ZNF611 -0.44 -5.92 -0.47 2.99e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7085104 0.700 rs743572 chr10:104597152 A/G cg04362960 chr10:104952993 NT5C2 0.57 5.05 0.41 1.54e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT trans rs931812 0.825 rs55818461 chr8:101899229 T/C cg20993868 chr7:22813445 NA 0.41 8.93 0.63 4.77e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs7666738 0.830 rs6855393 chr4:99056534 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg05665937 chr4:1216051 CTBP1 0.24 4.63 0.38 8.9e-6 Obesity-related traits; TGCT cis rs2836974 0.897 rs2026267 chr21:40711477 C/A cg11644478 chr21:40555479 PSMG1 0.88 8.03 0.59 6.26e-13 Cognitive function; TGCT cis rs11719291 0.833 rs11709246 chr3:48859498 G/A cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 Cognitive function; TGCT cis rs9467773 1.000 rs9467783 chr6:26542894 C/T cg09904177 chr6:26538194 HMGN4 0.64 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.525 rs2662016 chr5:56269047 A/G cg24549020 chr5:56110836 MAP3K1 -0.66 -4.97 -0.41 2.2e-6 Initial pursuit acceleration; TGCT cis rs769267 1.000 rs769267 chr19:19446936 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.68 5.69 0.46 8.51e-8 Tonsillectomy; TGCT trans rs2688608 0.653 rs12775558 chr10:75570868 G/A cg13918328 chr10:52500089 ASAH2B 0.7 6.95 0.53 1.83e-10 Inflammatory bowel disease; TGCT cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg12310025 chr6:25882481 NA 0.9 9.29 0.64 6.69e-16 Blood metabolite levels; TGCT cis rs57994353 0.578 rs10448340 chr9:139320069 A/C cg13741927 chr9:139327495 INPP5E -0.24 -6.06 -0.48 1.48e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9611565 0.921 rs5758297 chr22:41720697 A/G cg13695892 chr22:41940480 POLR3H -0.72 -7.33 -0.55 2.61e-11 Vitiligo; TGCT cis rs11264213 0.901 rs72661643 chr1:36451599 A/G cg27506609 chr1:36549197 TEKT2 0.41 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs17197710 0.673 rs12576461 chr11:47320772 T/C cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs589249 0.963 rs4652925 chr1:37179511 T/C cg04012535 chr1:37176647 NA 0.35 5.57 0.45 1.52e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs9512730 0.527 rs11619784 chr13:27999643 A/G cg04070771 chr13:27998621 GTF3A 0.61 5.33 0.43 4.55e-7 Schizophrenia; TGCT cis rs17376456 0.877 rs17374627 chr5:93296306 C/T cg25358565 chr5:93447407 FAM172A 0.95 8.01 0.58 7.25e-13 Diabetic retinopathy; TGCT cis rs1887596 0.624 rs9581701 chr13:27123670 T/C cg01312412 chr13:27282625 NA 0.26 4.59 0.38 1.09e-5 Facial morphology (factor 3, length of philtrum); TGCT cis rs1429606 1.000 rs9293493 chr5:87198583 C/T cg09451457 chr5:87440246 NA -0.69 -4.44 -0.37 2e-5 Number of children (6+ vs. 0 or 1); TGCT cis rs17253792 0.822 rs76205307 chr14:56166038 C/T cg01858014 chr14:56050164 KTN1 -0.35 -4.45 -0.37 1.9e-5 Putamen volume; TGCT cis rs7312933 0.558 rs4768399 chr12:42742696 G/A cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.18e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs17030434 0.784 rs11099896 chr4:154664697 T/G cg14289246 chr4:154710475 SFRP2 -0.87 -7.47 -0.56 1.24e-11 Electrocardiographic conduction measures; TGCT cis rs1801251 1.000 rs6714245 chr2:233580505 T/C cg08000102 chr2:233561755 GIGYF2 0.63 6.41 0.5 2.8e-9 Coronary artery disease; TGCT cis rs9611519 0.780 rs2235850 chr22:41657626 C/T cg03806693 chr22:41940476 POLR3H -0.74 -7.23 -0.54 4.46e-11 Neuroticism; TGCT cis rs28374715 0.662 rs28827035 chr15:41492290 G/A cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.53 -0.72 2.33e-21 Ulcerative colitis; TGCT cis rs9929218 0.581 rs7203337 chr16:68774800 C/G cg01251360 chr16:68772225 CDH1 -0.25 -4.55 -0.38 1.25e-5 Colorectal cancer; TGCT cis rs28595532 0.920 rs114796605 chr4:119744472 C/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg18252515 chr7:66147081 NA -1.22 -7.98 -0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs11673344 0.523 rs7248948 chr19:37547219 G/T cg08039142 chr19:36980659 ZNF566 0.51 4.69 0.39 7.03e-6 Obesity-related traits; TGCT cis rs1372520 0.748 rs1471484 chr4:90754313 C/T cg20003494 chr4:90757398 SNCA -0.6 -4.72 -0.39 6.34e-6 Neuroticism; TGCT cis rs732765 0.734 rs10130425 chr14:75185394 C/T cg06637938 chr14:75390232 RPS6KL1 -0.55 -4.48 -0.37 1.71e-5 Non-small cell lung cancer; TGCT cis rs875971 0.638 rs801216 chr7:66011667 T/C cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs1801251 0.778 rs2250665 chr2:233752639 A/T cg25237894 chr2:233734115 C2orf82 -0.31 -5.84 -0.46 4.25e-8 Coronary artery disease; TGCT cis rs7681440 0.967 rs1372517 chr4:90755909 G/A cg26578617 chr4:90757533 SNCA -0.48 -4.97 -0.41 2.15e-6 Dementia with Lewy bodies; TGCT cis rs1372520 0.623 rs2583975 chr4:90748488 T/C cg15133208 chr4:90757351 SNCA -0.5 -5.81 -0.46 4.96e-8 Neuroticism; TGCT cis rs6901250 0.522 rs693602 chr6:117085784 A/C cg12892004 chr6:117198278 RFX6 0.37 4.69 0.39 7.12e-6 C-reactive protein levels; TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg16325326 chr1:53192061 ZYG11B 0.63 7.34 0.55 2.51e-11 Monocyte count; TGCT cis rs896854 0.738 rs481887 chr8:95967838 A/G cg13393036 chr8:95962371 TP53INP1 0.56 6.67 0.51 7.41e-10 Type 2 diabetes; TGCT cis rs7666738 0.830 rs11941844 chr4:99042722 A/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7715806 0.500 rs3797581 chr5:75002895 G/T cg19683494 chr5:74908142 NA 0.53 4.63 0.38 9.15e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs4820539 0.902 rs4822359 chr22:23474972 A/G cg21100191 chr22:23484243 RTDR1 0.89 10.47 0.69 8.92e-19 Bone mineral density; TGCT cis rs2832191 1.000 rs2832190 chr21:30488226 G/A cg24692254 chr21:30365293 RNF160 -0.83 -8.71 -0.62 1.58e-14 Dental caries; TGCT cis rs990171 1.000 rs1420106 chr2:103035044 C/T cg04239558 chr2:103089729 SLC9A4 -0.33 -4.57 -0.38 1.16e-5 Lymphocyte counts; TGCT cis rs2859741 0.967 rs494157 chr1:37512995 C/T cg09363841 chr1:37513479 NA 0.19 4.68 0.39 7.42e-6 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs751728 1.000 rs2296748 chr6:33745071 C/T cg13859433 chr6:33739653 LEMD2 -0.39 -7.13 -0.54 7.29e-11 Crohn's disease; TGCT cis rs11514810 1.000 rs9648619 chr7:1427949 G/T cg24899294 chr7:1481343 MICALL2 -0.46 -6.22 -0.49 7.03e-9 Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder; TGCT cis rs2204008 0.715 rs11514282 chr12:38169056 G/T cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs9430161 0.611 rs72644043 chr1:11033051 T/A cg27631724 chr1:11040367 C1orf127 0.54 6.05 0.48 1.62e-8 Ewing sarcoma; TGCT cis rs2658782 1.000 rs2608216 chr11:93149172 G/A cg15737290 chr11:93063684 CCDC67 0.82 5.67 0.45 9.52e-8 Pulmonary function decline; TGCT cis rs2153535 0.580 rs9378554 chr6:8488468 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg26338869 chr17:61819248 STRADA -0.52 -4.73 -0.39 6e-6 Prudent dietary pattern; TGCT cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg03188948 chr7:1209495 NA 0.5 7.0 0.53 1.44e-10 Longevity;Endometriosis; TGCT cis rs7772486 0.875 rs10457795 chr6:146415665 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.618 rs8068820 chr17:17834119 A/G cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs13223928 0.651 rs4722426 chr7:3150697 C/T cg19214707 chr7:3157722 NA 0.49 7.19 0.54 5.38e-11 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs57920188 0.640 rs10915600 chr1:4082105 T/G cg20703997 chr1:4087676 NA 0.44 5.4 0.44 3.22e-7 Interleukin-17 levels; TGCT cis rs6964587 0.967 rs34863529 chr7:91644341 C/G cg17063962 chr7:91808500 NA 0.91 9.88 0.66 2.45e-17 Breast cancer; TGCT cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1729951 0.545 rs1097288 chr3:136693721 C/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs1670533 1.000 rs10026482 chr4:1051128 C/G cg20887711 chr4:1340912 KIAA1530 0.7 5.66 0.45 9.77e-8 Recombination rate (females); TGCT cis rs4730250 0.708 rs74983157 chr7:106823951 A/G cg02696742 chr7:106810147 HBP1 -0.7 -6.05 -0.48 1.59e-8 Osteoarthritis; TGCT cis rs752010 0.619 rs4393146 chr1:42118766 A/G cg06885757 chr1:42089581 HIVEP3 0.27 4.73 0.39 5.88e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs3749237 0.595 rs2878298 chr3:49406080 T/C cg02487422 chr3:49467188 NICN1 0.59 6.0 0.47 2.04e-8 Resting heart rate; TGCT cis rs1218582 0.772 rs906593 chr1:154885255 G/A cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs9467711 0.559 rs9348721 chr6:26485573 A/G cg16898833 chr6:26189333 HIST1H4D 0.94 4.58 0.38 1.12e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6671200 1.000 rs12749053 chr1:95660556 A/G cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs28374715 0.681 rs11629979 chr15:41626579 A/G cg18705301 chr15:41695430 NDUFAF1 -0.87 -13.45 -0.77 5.4e-26 Ulcerative colitis; TGCT cis rs9818758 0.607 rs35108630 chr3:49088356 T/A cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT trans rs9951602 0.512 rs4798995 chr18:76654344 T/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs2239547 0.562 rs6794389 chr3:53096394 A/G cg11645453 chr3:52864694 ITIH4 0.31 4.99 0.41 1.98e-6 Schizophrenia; TGCT cis rs3772130 0.564 rs35178434 chr3:121595936 G/A cg20356878 chr3:121714668 ILDR1 0.38 4.83 0.4 3.93e-6 Cognitive performance; TGCT cis rs6089829 1.000 rs62207535 chr20:61669187 A/G cg18188782 chr20:61659543 NA 0.47 5.68 0.45 9.19e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs8141529 0.673 rs132548 chr22:29317559 C/G cg02153584 chr22:29168773 CCDC117 -0.58 -4.6 -0.38 1.02e-5 Lymphocyte counts; TGCT cis rs5769707 0.609 rs135861 chr22:49998118 A/G cg06623630 chr22:50017776 C22orf34 -0.26 -4.44 -0.37 1.97e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4595586 0.545 rs11615638 chr12:39364766 A/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs11577318 0.853 rs4333841 chr1:26631927 T/C cg12733254 chr1:26682999 NA -0.2 -4.45 -0.37 1.89e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2180341 0.924 rs9285459 chr6:127631113 T/C cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs3617 0.573 rs9860296 chr3:52913781 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.5 4.76 0.39 5.23e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs7726839 0.507 rs56282020 chr5:596701 T/C cg25482853 chr8:67687455 SGK3 1.27 10.62 0.69 4.03e-19 Obesity-related traits; TGCT cis rs7726839 0.540 rs74553517 chr5:665671 C/T cg16624210 chr5:671434 TPPP 0.42 4.89 0.4 3.06e-6 Obesity-related traits; TGCT cis rs6933660 0.745 rs9322320 chr6:151751908 C/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.76 0.39 5.36e-6 Menarche (age at onset); TGCT cis rs854765 0.647 rs4426402 chr17:17977926 C/T cg04398451 chr17:18023971 MYO15A 0.36 6.16 0.48 9.27e-9 Total body bone mineral density; TGCT cis rs6748734 1.000 rs4675863 chr2:241830763 A/T cg04034577 chr2:241836375 C2orf54 -0.4 -6.32 -0.49 4.22e-9 Urinary metabolites; TGCT cis rs7208859 0.673 rs36056619 chr17:29172284 T/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs736408 0.522 rs998909 chr3:52805093 A/G cg07507251 chr3:52567010 NT5DC2 0.49 6.71 0.52 6.33e-10 Bipolar disorder; TGCT cis rs4727027 0.899 rs11768971 chr7:148825826 C/G cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3806843 0.576 rs246049 chr5:140327590 T/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs4664308 0.967 rs7563607 chr2:160910215 C/G cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs4319547 0.876 rs10846978 chr12:122964708 T/C cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.32 -0.43 4.71e-7 Body mass index; TGCT cis rs2562456 0.917 rs6511253 chr19:21678798 A/G cg25650185 chr19:21324782 ZNF431 0.57 5.08 0.42 1.35e-6 Pain; TGCT cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg22166914 chr1:53195759 ZYG11B -0.47 -8.65 -0.61 2.18e-14 Monocyte count; TGCT cis rs9611565 0.802 rs132916 chr22:41806768 C/G cg17554472 chr22:41940697 POLR3H 0.45 5.02 0.41 1.74e-6 Vitiligo; TGCT cis rs4924935 0.851 rs966811 chr17:18830287 G/A cg26378065 chr17:18585709 ZNF286B -0.55 -4.52 -0.38 1.44e-5 Pancreatic cancer; TGCT cis rs861020 1.000 rs680923 chr1:209986672 T/C cg05527609 chr1:210001259 C1orf107 0.91 7.4 0.55 1.84e-11 Orofacial clefts; TGCT cis rs9948 0.655 rs78424221 chr2:97410399 A/G cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7216064 1.000 rs6504548 chr17:65886048 T/C cg12091567 chr17:66097778 LOC651250 -0.84 -6.8 -0.52 4.01e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9649213 0.614 rs9640655 chr7:98017099 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.94 -8.9 -0.62 5.66e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs4975709 0.610 rs4975706 chr5:1860365 G/T cg12288994 chr5:1860383 NA 0.24 4.65 0.39 8.46e-6 Cardiovascular disease risk factors; TGCT cis rs9926296 0.715 rs467035 chr16:89740285 C/G cg26513180 chr16:89883248 FANCA 0.59 5.64 0.45 1.1e-7 Vitiligo; TGCT cis rs1801251 0.896 rs4973561 chr2:233687337 C/G cg08000102 chr2:233561755 GIGYF2 -0.53 -5.5 -0.44 2.04e-7 Coronary artery disease; TGCT cis rs7726839 0.540 rs72707016 chr5:665148 A/G cg20362242 chr5:692897 TPPP 0.51 4.66 0.39 8.11e-6 Obesity-related traits; TGCT cis rs1903068 0.853 rs12331597 chr4:55997914 T/C cg16572876 chr4:56024045 NA 0.47 5.29 0.43 5.35e-7 Endometriosis; TGCT cis rs3125734 0.633 rs12217669 chr10:63988456 A/G cg09941381 chr10:64027924 RTKN2 0.38 5.71 0.46 8.06e-8 Rheumatoid arthritis; TGCT cis rs7917772 0.508 rs2252147 chr10:104467774 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.67 5.76 0.46 6.18e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs981844 0.961 rs62325108 chr4:154679767 G/A cg14289246 chr4:154710475 SFRP2 1.04 8.89 0.62 6.07e-15 Response to statins (LDL cholesterol change); TGCT cis rs9647570 0.582 rs2973656 chr5:167280392 G/A cg11091196 chr5:167285540 ODZ2 0.32 5.0 0.41 1.88e-6 Menarche (age at onset); TGCT cis rs1218582 0.741 rs10908447 chr1:154869742 C/T cg24250549 chr1:154909240 PMVK 0.56 5.42 0.44 2.92e-7 Prostate cancer; TGCT cis rs2235642 0.826 rs8048410 chr16:1614097 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.34 -5.64 -0.45 1.1e-7 Coronary artery disease; TGCT cis rs7586879 0.551 rs7565460 chr2:25130073 C/T cg15423357 chr2:25149977 NA 0.5 4.87 0.4 3.29e-6 Body mass index; TGCT cis rs7937612 1.000 rs11217852 chr11:120261187 A/G cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.54 -0.38 1.32e-5 Intraocular pressure; TGCT trans rs10506458 1.000 rs12425932 chr12:63410497 C/A cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.48 -7.61 -0.56 5.87e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs2243480 1.000 rs316321 chr7:65611613 G/A cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs9814567 1.000 rs7427492 chr3:134261654 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.89 -0.66 2.32e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4589502 0.512 rs7183242 chr15:67096658 A/G cg12317470 chr15:67143691 NA 0.55 4.93 0.4 2.6e-6 Lung cancer (smoking interaction); TGCT cis rs2067615 0.579 rs7297592 chr12:107223969 G/T cg15890332 chr12:107067104 RFX4 0.29 5.79 0.46 5.36e-8 Heart rate; TGCT trans rs629535 0.814 rs549643 chr8:70062884 C/T cg21567404 chr3:27674614 NA 0.52 7.95 0.58 9.59e-13 Dupuytren's disease; TGCT cis rs763014 0.966 rs7198877 chr16:661439 A/G cg00908189 chr16:619842 PIGQ 0.86 10.25 0.68 3.12e-18 Height; TGCT cis rs317689 0.918 rs581911 chr12:69738293 C/T cg20891283 chr12:69753455 YEATS4 0.56 4.6 0.38 1.03e-5 Response to diuretic therapy; TGCT cis rs4660261 0.526 rs803680 chr1:44364370 G/C cg12908607 chr1:44402522 ARTN -0.67 -8.24 -0.59 2.07e-13 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.935 rs4573 chr6:26546808 A/G cg09904177 chr6:26538194 HMGN4 0.64 6.32 0.49 4.25e-9 Intelligence (multi-trait analysis); TGCT cis rs7611238 0.560 rs7653406 chr3:195040226 G/A cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.94e-6 Body mass index; TGCT cis rs7524258 0.868 rs916393 chr1:7272250 T/C cg07173049 chr1:7289937 CAMTA1 0.29 4.77 0.39 5.07e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7226408 0.948 rs72885222 chr18:34401184 G/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs2050392 0.861 rs1042058 chr10:30728101 T/C cg18806716 chr10:30721971 MAP3K8 -0.51 -6.0 -0.47 2.04e-8 Inflammatory bowel disease; TGCT cis rs9611565 0.694 rs5758389 chr22:41941749 T/C cg17554472 chr22:41940697 POLR3H -0.48 -5.46 -0.44 2.44e-7 Vitiligo; TGCT cis rs28595532 0.920 rs115154776 chr4:119774803 A/G cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs6565180 0.632 rs8050812 chr16:30385837 C/T cg17640201 chr16:30407289 ZNF48 -0.77 -6.12 -0.48 1.16e-8 Tonsillectomy; TGCT cis rs11030122 0.635 rs10835540 chr11:4071429 T/A cg08557956 chr11:4115526 RRM1 -0.56 -4.73 -0.39 5.93e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs9951602 0.607 rs3017651 chr18:76668622 T/C cg00806245 chr18:76673096 NA -0.3 -4.97 -0.41 2.18e-6 Obesity-related traits; TGCT cis rs244731 0.959 rs3105419 chr5:176551396 G/C cg16006841 chr5:176797999 RGS14 0.53 6.5 0.5 1.79e-9 Urate levels in lean individuals; TGCT cis rs2074585 0.618 rs2060854 chr15:90917827 C/T cg22089800 chr15:90895588 ZNF774 0.83 8.94 0.63 4.62e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs17102423 0.689 rs7158239 chr14:65520616 G/A cg11161011 chr14:65562177 MAX -0.47 -6.27 -0.49 5.52e-9 Obesity-related traits; TGCT cis rs7635838 0.617 rs346074 chr3:11294310 T/C cg00170343 chr3:11313890 ATG7 0.64 6.43 0.5 2.5e-9 HDL cholesterol; TGCT cis rs4700695 0.619 rs37230 chr5:65218264 A/C cg21114390 chr5:65439923 SFRS12 0.63 4.77 0.39 5.1e-6 Facial morphology (factor 19); TGCT cis rs7647973 0.961 rs6778080 chr3:49317338 C/T cg05785598 chr3:49045655 WDR6 -0.38 -4.59 -0.38 1.09e-5 Menarche (age at onset); TGCT cis rs1215050 0.791 rs983187 chr4:98816350 A/T cg05340658 chr4:99064831 C4orf37 0.45 5.78 0.46 5.8e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6921919 0.515 rs1339898 chr6:28395506 C/T cg18815343 chr6:28367644 ZSCAN12 -0.49 -4.9 -0.4 2.87e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1034435 0.755 rs5767172 chr22:48892314 A/C cg05992904 chr22:48892994 FAM19A5 -0.35 -4.77 -0.39 5.03e-6 Late-onset Alzheimer's disease; TGCT cis rs7584330 0.554 rs1343768 chr2:238444881 G/A cg08992911 chr2:238395768 MLPH 0.64 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs7552404 0.696 rs1417405 chr1:76457797 T/C cg03433033 chr1:76189801 ACADM 0.73 6.36 0.5 3.6e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10972341 0.900 rs4878605 chr9:35150720 C/T cg00812861 chr9:35114699 KIAA1539 0.33 4.92 0.4 2.64e-6 Weight; TGCT cis rs9611565 0.592 rs12484254 chr22:41962003 T/A cg06481639 chr22:41940642 POLR3H -0.67 -5.71 -0.46 7.87e-8 Vitiligo; TGCT cis rs6952808 0.723 rs55689856 chr7:2037215 G/A cg04267008 chr7:1944627 MAD1L1 -0.4 -5.28 -0.43 5.52e-7 Bipolar disorder and schizophrenia; TGCT cis rs61867294 0.794 rs6584633 chr10:106667382 C/T cg08000847 chr10:105880925 C10orf78 0.56 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs2486012 1.000 rs2248305 chr1:44379493 C/T cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.817 rs60646469 chr8:58195348 T/C cg08280861 chr8:58055591 NA 0.37 4.69 0.39 6.96e-6 Developmental language disorder (linguistic errors); TGCT cis rs9926296 0.533 rs12102297 chr16:89812762 C/A cg21285383 chr16:89894308 SPIRE2 0.42 6.41 0.5 2.82e-9 Vitiligo; TGCT cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs1552244 0.554 rs7638846 chr3:10048601 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.65 4.58 0.38 1.09e-5 Alzheimer's disease; TGCT cis rs651907 0.514 rs12636047 chr3:101434449 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.73 0.39 5.91e-6 Colorectal cancer; TGCT cis rs902774 0.554 rs4919749 chr12:53358034 C/T cg25025879 chr12:53359317 NA -0.46 -5.19 -0.42 8.37e-7 Prostate cancer; TGCT cis rs3862435 0.572 rs2601167 chr15:90912567 G/A cg14166756 chr15:90894880 ZNF774 -0.31 -4.88 -0.4 3.17e-6 Response to exercise (triglyceride level interaction); TGCT cis rs7909074 0.714 rs10900129 chr10:45398609 G/C cg04218760 chr10:45406644 TMEM72 -0.25 -4.62 -0.38 9.58e-6 Mean corpuscular volume; TGCT cis rs916888 0.773 rs199457 chr17:44795469 C/T cg15921436 chr17:44337874 NA 0.58 8.13 0.59 3.77e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7824557 0.628 rs34237267 chr8:11197301 G/C cg21775007 chr8:11205619 TDH 0.69 6.81 0.52 3.8e-10 Retinal vascular caliber; TGCT cis rs7772486 0.641 rs960385 chr6:146371074 G/A cg23711669 chr6:146136114 FBXO30 0.68 6.55 0.51 1.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 0.920 rs114670456 chr4:119771202 A/G cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs6586163 0.872 rs7069841 chr10:90741955 T/C cg03111039 chr10:90751583 FAS;ACTA2 -0.36 -4.47 -0.37 1.76e-5 Chronic lymphocytic leukemia; TGCT cis rs9467773 1.000 rs6925895 chr6:26572165 G/T cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs6684514 1.000 rs2241106 chr1:156218910 C/G cg20302342 chr1:156215951 PAQR6 0.37 4.73 0.39 6e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg10802521 chr3:52805072 NEK4 -0.74 -9.02 -0.63 2.87e-15 Bipolar disorder; TGCT cis rs9911578 1.000 rs9892795 chr17:57023054 G/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs4733781 0.829 rs4733770 chr8:131152665 G/A cg16277922 chr8:131349729 ASAP1 0.36 4.47 0.37 1.75e-5 Tuberculosis; TGCT cis rs116095464 0.558 rs57335027 chr5:262907 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs7552404 0.727 rs7547056 chr1:76279267 C/T cg03433033 chr1:76189801 ACADM 0.66 6.88 0.53 2.57e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9486719 1.000 rs2499809 chr6:96870110 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT trans rs7726839 0.561 rs6555357 chr5:560923 A/G cg11887960 chr12:57824829 NA 1.03 8.25 0.6 1.96e-13 Obesity-related traits; TGCT cis rs2295359 1.000 rs10889664 chr1:67635475 C/T cg12940439 chr1:67600707 NA 0.54 5.66 0.45 9.77e-8 Psoriasis; TGCT cis rs1568889 1.000 rs7949704 chr11:28373543 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.8 7.83 0.58 1.84e-12 Bipolar disorder; TGCT cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs35146811 0.657 rs36019559 chr7:99814586 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg14893161 chr1:205819251 PM20D1 0.53 7.12 0.54 7.78e-11 Menarche (age at onset); TGCT cis rs56235845 0.964 rs11746443 chr5:176798306 G/A cg17509989 chr5:176798049 RGS14 0.8 12.25 0.74 4.18e-23 Hemoglobin concentration;Hematocrit; TGCT cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg12756686 chr19:29218302 NA 0.78 6.69 0.51 6.93e-10 Methadone dose in opioid dependence; TGCT cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs10883723 0.810 rs10748823 chr10:104274465 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6725041 0.819 rs2049180 chr2:213081740 G/A cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT cis rs7647973 1.000 rs2312462 chr3:49601255 A/G cg06212747 chr3:49208901 KLHDC8B 0.55 4.5 0.37 1.55e-5 Menarche (age at onset); TGCT cis rs6977660 0.714 rs2390157 chr7:19786177 G/A cg05791153 chr7:19748676 TWISTNB 0.84 4.71 0.39 6.52e-6 Thyroid stimulating hormone; TGCT cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836974 0.897 rs2026265 chr21:40595517 G/A cg11644478 chr21:40555479 PSMG1 1.0 10.6 0.69 4.32e-19 Cognitive function; TGCT cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg20637647 chr7:64974828 NA 0.9 5.29 0.43 5.42e-7 Diabetic kidney disease; TGCT cis rs11098499 0.691 rs9307471 chr4:120261262 G/A cg09307838 chr4:120376055 NA 0.55 5.36 0.43 3.98e-7 Corneal astigmatism; TGCT cis rs2180341 0.538 rs11154402 chr6:127711932 C/A cg24812749 chr6:127587940 RNF146 0.61 5.39 0.44 3.45e-7 Breast cancer; TGCT cis rs9309473 0.660 rs62151564 chr2:73615449 A/G cg07208825 chr2:73871855 ALMS1P 0.25 4.54 0.38 1.33e-5 Metabolite levels; TGCT cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg10802521 chr3:52805072 NEK4 -0.74 -9.22 -0.64 9.87e-16 Bipolar disorder; TGCT cis rs1156327 0.655 rs179225 chr16:19317985 C/T cg27311092 chr16:19142612 NA 0.49 4.47 0.37 1.74e-5 Periodontal disease-related phenotypes; TGCT cis rs7666738 0.830 rs4441757 chr4:98927059 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2191566 1.000 rs369106 chr19:44506930 C/T cg03039196 chr19:44506973 ZNF230 -0.54 -4.76 -0.39 5.23e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs6088580 0.570 rs6058057 chr20:33065283 G/A cg06115741 chr20:33292138 TP53INP2 0.52 4.47 0.37 1.75e-5 Glomerular filtration rate (creatinine); TGCT cis rs9811920 0.638 rs793503 chr3:99588070 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.58 -6.76 -0.52 4.82e-10 Axial length; TGCT cis rs9633740 1.000 rs7910643 chr10:82251769 G/A cg01528321 chr10:82214614 TSPAN14 1.0 8.33 0.6 1.25e-13 Post bronchodilator FEV1; TGCT cis rs250677 0.687 rs250674 chr5:148438597 A/G cg18129178 chr5:148520854 ABLIM3 0.42 6.27 0.49 5.53e-9 Breast cancer; TGCT cis rs10782582 0.593 rs11164042 chr1:76178440 G/A cg10523679 chr1:76189770 ACADM -0.69 -7.19 -0.54 5.39e-11 Daytime sleep phenotypes; TGCT cis rs889312 0.500 rs865570 chr5:56161975 C/T cg12311346 chr5:56204834 C5orf35 -0.46 -5.0 -0.41 1.87e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs2180341 0.751 rs9388553 chr6:127574044 A/G cg24812749 chr6:127587940 RNF146 0.83 6.69 0.51 6.91e-10 Breast cancer; TGCT cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.13 9.74 0.66 5.47e-17 Platelet count; TGCT cis rs9914988 0.943 rs9913801 chr17:27132105 G/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2580764 0.566 rs2972075 chr2:55292322 T/G cg09592903 chr2:55203963 RTN4 0.23 5.06 0.41 1.47e-6 Mean platelet volume; TGCT cis rs12142240 0.698 rs56909107 chr1:46808224 A/C cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs975752 0.717 rs7082753 chr10:102008483 A/G cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs9341808 0.652 rs2505940 chr6:80851191 T/C cg08355045 chr6:80787529 NA 0.32 5.38 0.43 3.6e-7 Sitting height ratio; TGCT cis rs2241685 0.920 rs59907143 chr2:1934163 T/C cg21862353 chr2:1801628 MYT1L -0.53 -4.86 -0.4 3.47e-6 Attention deficit hyperactivity disorder; TGCT cis rs2228479 0.850 rs62056069 chr16:89912000 C/T cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs7681440 0.647 rs11941110 chr4:90819569 T/C cg20003494 chr4:90757398 SNCA -0.51 -4.54 -0.38 1.33e-5 Dementia with Lewy bodies; TGCT cis rs7772486 0.790 rs9403750 chr6:146167762 G/A cg23711669 chr6:146136114 FBXO30 0.92 10.44 0.68 1.06e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs10001701 chr4:98918871 G/C cg05340658 chr4:99064831 C4orf37 0.53 6.12 0.48 1.13e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs2862064 0.872 rs6555776 chr5:156403505 C/A cg12943317 chr5:156479607 HAVCR1 -0.39 -5.15 -0.42 1.01e-6 Platelet count; TGCT cis rs3796352 0.892 rs9756317 chr3:53088815 T/C cg15956490 chr3:53032818 SFMBT1 -0.54 -6.44 -0.5 2.33e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs933688 0.938 rs10942634 chr5:90658392 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 9.41 0.65 3.47e-16 Smoking behavior; TGCT cis rs1801251 0.896 rs2305141 chr2:233684402 A/G cg08000102 chr2:233561755 GIGYF2 -0.58 -5.97 -0.47 2.3e-8 Coronary artery disease; TGCT cis rs877282 0.898 rs11253349 chr10:765897 C/G cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs79349575 0.783 rs62075818 chr17:46982327 T/A cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs77372450 0.551 rs3749797 chr5:157078475 C/G cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.48e-6 Bipolar disorder (body mass index interaction); TGCT cis rs4478858 0.735 rs12563669 chr1:31858067 A/G cg00250761 chr1:31883323 NA -0.25 -4.56 -0.38 1.22e-5 Alcohol dependence; TGCT cis rs4788570 0.625 rs2434885 chr16:71583859 C/T cg06353428 chr16:71660113 MARVELD3 -0.96 -6.91 -0.53 2.2e-10 Intelligence (multi-trait analysis); TGCT cis rs11874712 1.000 rs11082509 chr18:43655010 G/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs35146811 0.735 rs2272345 chr7:99797031 C/G cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs2245008 0.950 rs824400 chr16:83989936 C/G cg27171569 chr16:83987465 OSGIN1 -0.56 -6.3 -0.49 4.65e-9 Pursuit maintenance gain; TGCT trans rs1005277 0.579 rs1780138 chr10:38501654 A/G cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs4149178 1.000 rs4149178 chr6:43272188 A/G cg08373528 chr6:42672105 PRPH2 0.47 4.59 0.38 1.08e-5 Urate levels; TGCT cis rs114540395 1.000 rs114540395 chr10:103479062 C/T cg24291461 chr10:102749544 C10orf2 0.35 4.65 0.39 8.4e-6 Schizophrenia; TGCT cis rs3617 0.625 rs2240917 chr3:52851137 T/C cg10802521 chr3:52805072 NEK4 -0.6 -6.89 -0.53 2.46e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6952808 1.000 rs6977733 chr7:1886725 A/T cg22963979 chr7:1858916 MAD1L1 0.36 5.56 0.45 1.58e-7 Bipolar disorder and schizophrenia; TGCT cis rs11247915 0.600 rs12059495 chr1:26655614 A/G cg01414934 chr1:26605969 SH3BGRL3 0.21 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs2235642 0.928 rs1057610 chr16:1605537 T/C cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.75 -0.46 6.52e-8 Coronary artery disease; TGCT cis rs854765 0.856 rs2955382 chr17:17947710 C/T cg04398451 chr17:18023971 MYO15A 0.29 4.51 0.38 1.48e-5 Total body bone mineral density; TGCT cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs7095607 0.630 rs10998012 chr10:69958690 A/G cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs7246657 0.722 rs10409605 chr19:38123137 T/G cg03611452 chr19:38183253 ZNF781 0.59 4.76 0.39 5.34e-6 Coronary artery calcification; TGCT cis rs28595532 0.841 rs115924581 chr4:119786333 T/C cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs7017914 0.967 rs6472539 chr8:71629810 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs637571 0.522 rs493899 chr11:65747952 A/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.65 6.4 0.5 2.96e-9 Eosinophil percentage of white cells; TGCT cis rs9914544 0.966 rs9906795 chr17:18816740 G/A cg26378065 chr17:18585709 ZNF286B 0.52 4.64 0.38 8.75e-6 Educational attainment (years of education); TGCT cis rs8141529 0.509 rs5762864 chr22:29253364 T/C cg02153584 chr22:29168773 CCDC117 0.59 4.65 0.39 8.49e-6 Lymphocyte counts; TGCT cis rs7666738 0.830 rs28761309 chr4:98867393 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2637266 0.703 rs4437973 chr10:78484971 G/A cg18941641 chr10:78392320 NA 0.41 4.98 0.41 2.11e-6 Pulmonary function; TGCT cis rs447735 0.537 rs7190341 chr16:89917537 T/C cg27121462 chr16:89883253 FANCA 0.57 4.95 0.41 2.36e-6 Hemoglobin concentration; TGCT cis rs72945132 0.882 rs7929271 chr11:70165749 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs4722166 0.630 rs13311155 chr7:22789789 A/C cg26061582 chr7:22766209 IL6 0.57 7.17 0.54 5.91e-11 Lung cancer; TGCT cis rs9527 0.590 rs1541213 chr10:104885330 A/G cg04362960 chr10:104952993 NT5C2 0.69 5.82 0.46 4.78e-8 Arsenic metabolism; TGCT cis rs17401966 0.838 rs4846206 chr1:10310258 G/C cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg10117171 chr1:25599238 RHD -0.3 -4.95 -0.41 2.37e-6 Erythrocyte sedimentation rate; TGCT cis rs11578119 0.713 rs10800520 chr1:170382131 G/A cg09767346 chr1:170501363 GORAB -0.59 -4.92 -0.4 2.72e-6 Male-pattern baldness; TGCT cis rs1018836 0.608 rs12679836 chr8:91465287 A/G cg16814680 chr8:91681699 NA -0.73 -7.61 -0.56 5.91e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs17401966 0.838 rs11580854 chr1:10293565 G/A cg19773385 chr1:10388646 KIF1B -0.23 -4.99 -0.41 1.97e-6 Hepatocellular carcinoma; TGCT cis rs7618915 1.000 rs34569561 chr3:52287293 T/C cg07507251 chr3:52567010 NT5DC2 0.43 5.83 0.46 4.46e-8 Bipolar disorder; TGCT cis rs62244186 0.659 rs9311358 chr3:44538748 C/G cg02073558 chr3:44770973 ZNF501 0.61 5.85 0.47 4.09e-8 Depressive symptoms; TGCT cis rs58688157 0.960 rs10902178 chr11:612843 T/G cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs10791097 0.935 rs4601795 chr11:130729430 T/C cg05962950 chr11:130786565 SNX19 0.74 8.51 0.61 4.71e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs8017423 0.605 rs8181930 chr14:90811289 A/G cg04374321 chr14:90722782 PSMC1 -0.58 -5.68 -0.45 9.14e-8 Mortality in heart failure; TGCT cis rs2070488 0.761 rs6807940 chr3:38460062 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.73 7.17 0.54 5.95e-11 Electrocardiographic conduction measures; TGCT cis rs854765 0.647 rs7406744 chr17:17981938 C/G cg04398451 chr17:18023971 MYO15A -0.36 -6.28 -0.49 5.29e-9 Total body bone mineral density; TGCT cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.41 2.55e-6 Obesity-related traits; TGCT cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.92 7.33 0.55 2.53e-11 Platelet count; TGCT cis rs13191362 1.000 rs60719662 chr6:163006643 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs854765 0.964 rs12950562 chr17:17995166 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.63 -5.96 -0.47 2.46e-8 Total body bone mineral density; TGCT cis rs9399135 0.967 rs6923765 chr6:135335176 C/G cg24558204 chr6:135376177 HBS1L -0.48 -4.81 -0.4 4.28e-6 Red blood cell count; TGCT cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs7552404 0.924 rs1611823 chr1:76221706 T/G cg22875332 chr1:76189707 ACADM 0.69 8.32 0.6 1.32e-13 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1451375 0.729 rs6593017 chr7:50644812 G/A cg18232548 chr7:50535776 DDC 0.44 6.83 0.52 3.36e-10 Malaria; TGCT cis rs7267979 1.000 rs6515651 chr20:25414539 T/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1056107 0.931 rs3908938 chr9:114991220 C/G cg02332936 chr9:115140584 NA -0.25 -4.45 -0.37 1.89e-5 Colorectal cancer; TGCT cis rs7599312 0.534 rs2128321 chr2:213405276 G/T cg16329650 chr2:213403929 ERBB4 1.01 15.21 0.81 3.96e-30 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs611744 0.967 rs689256 chr8:109186398 T/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs9467773 0.935 rs9461270 chr6:26544110 A/G cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.11e-23 Intelligence (multi-trait analysis); TGCT cis rs4713118 0.513 rs156734 chr6:28007357 A/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.56 0.38 1.19e-5 Parkinson's disease; TGCT cis rs11190604 0.767 rs7076606 chr10:102192267 T/C cg16005271 chr10:102321736 NA 0.45 4.7 0.39 6.81e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12776158 0.792 rs12413268 chr10:71205504 G/A cg12610070 chr10:71211762 TSPAN15 -0.58 -5.04 -0.41 1.64e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs4699588 chr4:98973789 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1215050 0.740 rs783963 chr4:98989070 A/G cg05340658 chr4:99064831 C4orf37 0.41 4.84 0.4 3.81e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9916302 0.904 rs9894500 chr17:37515735 G/C cg07936489 chr17:37558343 FBXL20 0.64 4.93 0.4 2.62e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.683 rs6984765 chr8:58127124 T/C cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs950776 0.613 rs12915539 chr15:78940795 T/A cg21242079 chr15:79101063 ADAMTS7 -0.31 -4.76 -0.39 5.21e-6 Sudden cardiac arrest; TGCT cis rs12257961 0.579 rs6602837 chr10:15370901 A/G cg10616319 chr10:15468812 NA -0.26 -4.72 -0.39 6.16e-6 Selective IgA deficiency; TGCT cis rs1580019 0.922 rs766658 chr7:32499391 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.7 0.57 3.71e-12 Cognitive ability; TGCT cis rs4938534 0.750 rs1944927 chr11:111287404 C/A cg01212326 chr11:111250286 POU2AF1 -0.23 -4.83 -0.4 3.94e-6 Primary biliary cholangitis; TGCT cis rs7772486 0.875 rs6570738 chr6:146412695 G/A cg23711669 chr6:146136114 FBXO30 0.86 9.3 0.64 6.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs7745043 chr6:8513507 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.9 -0.4 2.9e-6 Bipolar disorder; TGCT cis rs11779988 0.545 rs208762 chr8:17806734 G/A cg01800426 chr8:17659068 MTUS1 -0.64 -4.99 -0.41 2.02e-6 Breast cancer; TGCT cis rs7666738 0.784 rs4699602 chr4:99034903 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs67073037 0.955 rs12620770 chr2:29144892 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs9787249 1.000 rs9787249 chr1:40212878 G/A cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs854765 0.822 rs1889014 chr17:17767165 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.64 -6.37 -0.5 3.37e-9 Total body bone mineral density; TGCT cis rs68170813 0.559 rs997311 chr7:106953033 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs1218582 0.774 rs11264284 chr1:154875793 C/T cg24250549 chr1:154909240 PMVK 0.56 5.42 0.44 2.92e-7 Prostate cancer; TGCT cis rs2204008 0.775 rs11514369 chr12:38305411 C/T cg26384229 chr12:38710491 ALG10B 0.82 7.18 0.54 5.6e-11 Bladder cancer; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg11494091 chr17:61959527 GH2 0.61 14.4 0.79 3.14e-28 Prudent dietary pattern; TGCT cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT cis rs6121246 0.529 rs6060296 chr20:30198480 T/C cg18721089 chr20:30220636 NA -0.57 -6.19 -0.49 7.9e-9 Mean corpuscular hemoglobin; TGCT cis rs597539 0.652 rs496616 chr11:68672800 G/C cg06028808 chr11:68637592 NA 0.53 6.91 0.53 2.23e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9894429 0.671 rs6565616 chr17:79612161 C/T cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs2734839 0.537 rs1554929 chr11:113278764 C/T cg14159747 chr11:113255604 NA 0.38 4.97 0.41 2.22e-6 Information processing speed; TGCT cis rs9926296 0.605 rs6500449 chr16:89856393 T/C cg21285383 chr16:89894308 SPIRE2 0.46 7.19 0.54 5.44e-11 Vitiligo; TGCT cis rs853679 0.517 rs9380050 chr6:28048538 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs57590327 0.528 rs2229519 chr3:81698130 T/C cg07356753 chr3:81810745 GBE1 -0.77 -6.97 -0.53 1.63e-10 Extraversion; TGCT cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg10117171 chr1:25599238 RHD 0.3 4.92 0.4 2.69e-6 Erythrocyte sedimentation rate; TGCT cis rs372883 0.648 rs15092 chr21:30718201 G/A cg24692254 chr21:30365293 RNF160 -0.52 -4.7 -0.39 6.8e-6 Pancreatic cancer; TGCT cis rs7119 0.604 rs2682927 chr15:77859168 C/T cg27398640 chr15:77910606 LINGO1 0.27 4.82 0.4 4.2e-6 Type 2 diabetes; TGCT cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs10276381 0.892 rs7786444 chr7:28154384 C/T cg23620719 chr7:28220237 JAZF1 0.81 5.22 0.42 7.21e-7 Crohn's disease; TGCT cis rs11175492 0.528 rs7302505 chr12:65018121 T/G cg18624581 chr12:65153313 GNS -0.82 -4.69 -0.39 7.05e-6 Platelet count; TGCT trans rs797680 0.856 rs7547244 chr1:93781768 A/G cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs17221829 0.733 rs10830333 chr11:89399224 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 1.93e-5 Anxiety in major depressive disorder; TGCT cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg17264618 chr3:40429014 ENTPD3 0.35 4.87 0.4 3.3e-6 Renal cell carcinoma; TGCT cis rs7246657 0.722 rs10402671 chr19:38117086 C/T cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs7772486 0.754 rs9373475 chr6:146126419 C/T cg13319975 chr6:146136371 FBXO30 -0.57 -5.13 -0.42 1.07e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs2727020 0.638 rs1164668 chr11:49330627 A/C cg15704280 chr7:45808275 SEPT13 0.69 7.76 0.57 2.73e-12 Coronary artery disease; TGCT cis rs8141529 0.732 rs6005872 chr22:29172898 T/G cg02153584 chr22:29168773 CCDC117 0.69 5.96 0.47 2.47e-8 Lymphocyte counts; TGCT cis rs17826219 0.706 rs28469200 chr17:29133572 T/A cg13385521 chr17:29058706 SUZ12P 0.81 4.92 0.4 2.74e-6 Body mass index; TGCT trans rs6089829 0.962 rs2277769 chr20:61666805 C/T cg13615516 chr5:77269221 NA 0.7 8.83 0.62 8.34e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs875971 0.505 rs1167385 chr7:65513308 G/A cg18876405 chr7:65276391 NA -0.36 -5.71 -0.46 7.96e-8 Aortic root size; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg09509183 chr1:209979624 IRF6 0.52 5.12 0.42 1.16e-6 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs936229 0.871 rs2290574 chr15:75135447 T/C cg10253484 chr15:75165896 SCAMP2 -0.78 -6.51 -0.5 1.67e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs936229 1.000 rs936229 chr15:75132319 A/G cg10253484 chr15:75165896 SCAMP2 -0.79 -6.56 -0.51 1.31e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs2188554 1.000 rs2188554 chr7:117040117 A/G cg08576598 chr7:116962626 WNT2 -0.4 -5.07 -0.41 1.4e-6 Esophageal adenocarcinoma; TGCT cis rs4589502 0.925 rs57729347 chr15:67136438 G/A cg12317470 chr15:67143691 NA 0.66 5.43 0.44 2.9e-7 Lung cancer (smoking interaction); TGCT cis rs2836974 0.666 rs1888487 chr21:40683259 A/G cg11644478 chr21:40555479 PSMG1 -0.62 -5.52 -0.44 1.88e-7 Cognitive function; TGCT cis rs79057730 0.599 rs34411410 chr7:811721 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.65 6.07 0.48 1.41e-8 Initial pursuit acceleration; TGCT cis rs7588654 0.793 rs17608726 chr2:219947002 G/A cg19394737 chr2:219892361 CCDC108 -0.35 -4.55 -0.38 1.27e-5 Height; TGCT cis rs7833790 0.660 rs67666182 chr8:82772037 A/G cg23324259 chr8:82754387 SNX16 0.62 4.71 0.39 6.47e-6 Diastolic blood pressure; TGCT cis rs2742417 0.935 rs2248991 chr3:45754749 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2688608 0.620 rs7098444 chr10:75580042 C/T cg15838173 chr10:75533400 FUT11 -0.3 -4.83 -0.4 3.97e-6 Inflammatory bowel disease; TGCT cis rs1218582 0.596 rs906595 chr1:154822907 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.49 -4.67 -0.39 7.72e-6 Prostate cancer; TGCT cis rs7914558 1.000 rs3740387 chr10:104849468 G/A cg04362960 chr10:104952993 NT5C2 0.62 5.42 0.44 2.99e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs11190604 1.000 rs9420782 chr10:102235015 G/A cg16342193 chr10:102329863 NA -0.39 -5.14 -0.42 1.03e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7208859 0.623 rs7220289 chr17:29103762 G/T cg13385521 chr17:29058706 SUZ12P 0.81 4.84 0.4 3.86e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2836974 0.563 rs6517522 chr21:40553845 T/C cg11890956 chr21:40555474 PSMG1 0.88 9.47 0.65 2.49e-16 Cognitive function; TGCT cis rs2692947 0.644 rs1168974 chr2:96814928 G/A cg23100626 chr2:96804247 ASTL 0.46 5.42 0.44 3.03e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs28386778 0.799 rs2665802 chr17:61995030 A/T cg22520471 chr17:61851767 DDX42;CCDC47 -0.53 -5.12 -0.42 1.11e-6 Prudent dietary pattern; TGCT cis rs9549367 0.789 rs12584981 chr13:113881185 T/C cg00898013 chr13:113819073 PROZ -0.4 -4.88 -0.4 3.18e-6 Platelet distribution width; TGCT cis rs9486715 0.838 rs7452350 chr6:96883326 C/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs11148252 0.967 rs11618716 chr13:53046836 A/G cg00495681 chr13:53174319 NA -0.5 -5.08 -0.42 1.34e-6 Lewy body disease; TGCT cis rs10875595 0.779 rs2338532 chr5:140675264 G/A cg20560182 chr5:140700478 TAF7 -0.64 -4.91 -0.4 2.76e-6 Pulmonary function decline; TGCT trans rs797680 0.964 rs2152358 chr1:93634009 G/A cg27528825 chr2:159282178 CCDC148 -0.34 -6.63 -0.51 9.04e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9818758 0.607 rs9847839 chr3:49289003 T/C cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs17102423 0.573 rs7144259 chr14:65537559 T/A cg11161011 chr14:65562177 MAX -0.55 -6.8 -0.52 3.84e-10 Obesity-related traits; TGCT cis rs7731657 0.537 rs6867710 chr5:130201260 A/C cg08523029 chr5:130500466 HINT1 -0.55 -4.57 -0.38 1.15e-5 Fasting plasma glucose; TGCT cis rs4589502 0.925 rs4259997 chr15:67153310 A/G cg12317470 chr15:67143691 NA -0.57 -4.88 -0.4 3.2e-6 Lung cancer (smoking interaction); TGCT cis rs12580194 0.593 rs61556775 chr12:55745640 A/C cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs4665809 0.941 rs1434079 chr2:26284670 C/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs3806843 0.735 rs801185 chr5:140068869 A/G cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs1532993 0.518 rs13138073 chr4:98566397 G/A cg05340658 chr4:99064831 C4orf37 -0.38 -4.53 -0.38 1.36e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs950027 0.549 rs2899375 chr15:45598335 G/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.32e-11 Response to fenofibrate (adiponectin levels); TGCT cis rs2204008 0.536 rs12368354 chr12:38042798 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.23 0.42 7.11e-7 Bladder cancer; TGCT cis rs7474896 0.616 rs1985260 chr10:38434090 C/T cg25427524 chr10:38739819 LOC399744 -0.36 -4.55 -0.38 1.24e-5 Obesity (extreme); TGCT cis rs36051895 0.632 rs10974980 chr9:5140671 C/G cg02405213 chr9:5042618 JAK2 -0.7 -9.44 -0.65 2.91e-16 Pediatric autoimmune diseases; TGCT cis rs861020 0.771 rs126280 chr1:210019824 A/G cg05527609 chr1:210001259 C1orf107 1.05 10.03 0.67 1.07e-17 Orofacial clefts; TGCT cis rs2594989 0.943 rs2252601 chr3:11481234 A/G cg26283222 chr3:11613257 VGLL4 -0.21 -4.45 -0.37 1.92e-5 Circulating chemerin levels; TGCT cis rs6912958 0.525 rs59322 chr6:88020521 C/A cg08069147 chr6:88032118 GJB7;C6orf162 0.7 6.93 0.53 2.02e-10 Monocyte percentage of white cells; TGCT cis rs7772486 0.869 rs2777473 chr6:146301494 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 9.88e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs875971 0.929 rs778712 chr7:65849978 C/T cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs916888 0.773 rs199443 chr17:44819565 C/T cg17911788 chr17:44343683 NA -0.67 -7.15 -0.54 6.59e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2235642 1.000 rs2076438 chr16:1584618 T/C cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.35 -0.43 4.01e-7 Coronary artery disease; TGCT cis rs2439831 1.000 rs537115 chr15:43729948 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs4319547 0.656 rs3817011 chr12:122819566 C/T cg08088222 chr12:122070432 ORAI1 0.26 4.69 0.39 6.99e-6 Body mass index; TGCT cis rs7617773 0.780 rs4392440 chr3:48343920 C/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs597539 0.521 rs2060982 chr11:68612927 A/G cg06112835 chr11:68658793 MRPL21 0.32 5.31 0.43 4.95e-7 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs514475 0.526 rs12199435 chr6:137954339 G/A cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs854572 1.000 rs854572 chr7:94954696 C/G cg20119798 chr7:94954144 PON1 -0.28 -4.52 -0.38 1.45e-5 Paraoxonase activity; TGCT cis rs1059312 0.771 rs7974764 chr12:129296588 G/C cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs9916302 0.861 rs752314 chr17:37410700 C/T cg07936489 chr17:37558343 FBXL20 -0.63 -4.99 -0.41 2.03e-6 Glomerular filtration rate (creatinine); TGCT cis rs1023500 1.000 rs7293091 chr22:42341308 A/G cg04692870 chr22:42525206 CYP2D6 -0.33 -5.0 -0.41 1.9e-6 Schizophrenia; TGCT cis rs67614146 1 rs67614146 chr6:87821827 AC/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.65 -6.42 -0.5 2.63e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs796364 0.806 rs79333757 chr2:200915716 T/C cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs1865760 0.927 rs6915834 chr6:25935427 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.15 0.48 9.9e-9 Height; TGCT cis rs9611519 1.000 rs9611510 chr22:41569124 T/C cg03806693 chr22:41940476 POLR3H -0.67 -6.19 -0.49 7.94e-9 Neuroticism; TGCT cis rs7809950 0.817 rs2204833 chr7:107283069 T/C cg23024343 chr7:107201750 COG5 0.42 5.9 0.47 3.27e-8 Coronary artery disease; TGCT cis rs2230307 0.536 rs57637634 chr1:100447467 G/A cg24955406 chr1:100503596 HIAT1 0.72 4.68 0.39 7.51e-6 Carotid intima media thickness; TGCT cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg02187348 chr16:89574699 SPG7 0.61 6.52 0.51 1.61e-9 Multiple myeloma (IgH translocation); TGCT cis rs4253772 0.530 rs6008774 chr22:46755298 C/G cg24881330 chr22:46731750 TRMU 0.94 6.42 0.5 2.64e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs2898681 0.519 rs3811781 chr4:53729166 T/G cg00791764 chr4:53727839 RASL11B 0.54 4.58 0.38 1.1e-5 Optic nerve measurement (cup area); TGCT cis rs6456156 0.586 rs2285148 chr6:167490999 G/T cg07741184 chr6:167504864 NA 0.24 4.72 0.39 6.21e-6 Primary biliary cholangitis; TGCT cis rs2242116 0.796 rs4683297 chr3:46973673 T/C cg02527881 chr3:46936655 PTH1R 0.33 6.23 0.49 6.54e-9 Birth weight; TGCT cis rs2067615 0.542 rs7133161 chr12:107139540 A/G cg15890332 chr12:107067104 RFX4 0.3 5.93 0.47 2.85e-8 Heart rate; TGCT trans rs7698623 0.850 rs4693192 chr4:88797913 T/C cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs1505368 0.505 rs1394781 chr2:213248822 C/T cg16329650 chr2:213403929 ERBB4 -0.59 -5.15 -0.42 9.99e-7 Symmetrical dimethylarginine levels; TGCT cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.95 9.68 0.66 7.34e-17 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.791 rs10010438 chr4:99022177 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.6 6.44 0.5 2.39e-9 Height; TGCT cis rs7267979 0.934 rs2261115 chr20:25259807 G/A cg16686733 chr20:25566563 NINL 0.61 6.07 0.48 1.44e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1215050 0.547 rs6822735 chr4:98613915 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg04389838 chr3:44770851 ZNF501 -0.42 -5.54 -0.45 1.73e-7 Depressive symptoms; TGCT cis rs40363 1.000 rs37767 chr16:3514962 C/T cg22508957 chr16:3507546 NAT15 0.57 5.15 0.42 1.01e-6 Tuberculosis; TGCT trans rs208520 0.690 rs12198297 chr6:66714665 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg06035815 chr6:26189597 HIST1H4D 0.44 4.52 0.38 1.41e-5 Schizophrenia; TGCT cis rs2153535 0.580 rs2184583 chr6:8447808 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT trans rs7819412 0.511 rs7464263 chr8:11434176 A/T cg15556689 chr8:8085844 FLJ10661 -0.77 -7.2 -0.54 5.08e-11 Triglycerides; TGCT cis rs6831352 0.918 rs4699713 chr4:100060513 C/T cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs11785693 0.862 rs11782556 chr8:5002389 C/G cg26367366 chr8:4980734 NA 0.56 4.44 0.37 1.95e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs7666738 0.830 rs13102652 chr4:99006737 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.508 rs2516832 chr2:99771268 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs798766 1.000 rs798767 chr4:1734281 A/G cg05874882 chr4:1763078 NA -0.35 -4.45 -0.37 1.86e-5 Bladder cancer;Urinary bladder cancer; TGCT cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg27286337 chr10:134555280 INPP5A 0.46 5.5 0.44 2.08e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9534288 0.742 rs1977395 chr13:46638131 C/T cg15192986 chr13:46630673 CPB2 -0.54 -6.99 -0.53 1.48e-10 Blood protein levels; TGCT cis rs453301 0.658 rs13271797 chr8:8885954 G/A cg15556689 chr8:8085844 FLJ10661 -0.66 -5.4 -0.44 3.27e-7 Joint mobility (Beighton score); TGCT cis rs6121246 0.954 rs7266148 chr20:30431070 G/T cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs6901250 0.851 rs2175622 chr6:117149667 T/A cg12892004 chr6:117198278 RFX6 0.54 6.65 0.51 8.24e-10 C-reactive protein levels; TGCT cis rs6500602 0.647 rs4786514 chr16:4576798 A/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 5.16 0.42 9.66e-7 Schizophrenia; TGCT cis rs4372836 0.964 rs4665432 chr2:28952026 G/A cg09522027 chr2:28974177 PPP1CB 0.59 5.15 0.42 1e-6 Body mass index; TGCT trans rs10506458 0.915 rs17687426 chr12:63397900 G/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs875971 1.000 rs778696 chr7:65870813 C/G cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs72945132 0.882 rs11235967 chr11:70191691 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs17376456 0.877 rs10476601 chr5:93402522 G/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs12188164 0.965 rs56146525 chr5:442571 A/C cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs35306767 0.714 rs67696450 chr10:1090684 C/T cg18964960 chr10:1102726 WDR37 0.68 4.77 0.39 5.02e-6 Eosinophil percentage of granulocytes; TGCT cis rs7772486 0.875 rs2814874 chr6:146305895 C/T cg13319975 chr6:146136371 FBXO30 -0.52 -4.62 -0.38 9.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467711 0.606 rs2393667 chr6:26421345 T/C cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9457247 1.000 rs416131 chr6:167406544 A/C cg23791538 chr6:167370224 RNASET2 0.47 4.74 0.39 5.81e-6 Crohn's disease; TGCT cis rs1401999 0.546 rs56889301 chr3:183675315 T/C cg01324343 chr3:183735012 ABCC5 0.75 8.96 0.63 4.06e-15 Anterior chamber depth; TGCT cis rs35160687 0.901 rs10520415 chr2:86498738 C/T cg12542933 chr2:85804724 VAMP8 -0.4 -4.82 -0.4 4.16e-6 Night sleep phenotypes; TGCT cis rs155076 1.000 rs566364 chr13:21837583 T/C cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs12134133 1.000 rs10494890 chr1:207424386 C/G cg02152968 chr1:207494213 CD55 -0.62 -4.79 -0.4 4.64e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7552404 0.924 rs1313071 chr1:76195542 C/G cg03433033 chr1:76189801 ACADM 0.77 9.31 0.64 5.74e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28595532 0.841 rs114385163 chr4:119737058 C/T cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs739496 0.615 rs624716 chr12:112166696 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs7833790 0.777 rs7815272 chr8:82691809 T/G cg06027949 chr8:82754900 SNX16 -0.67 -4.47 -0.37 1.75e-5 Diastolic blood pressure; TGCT cis rs2050392 0.590 rs685319 chr10:30719331 G/A cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT cis rs10114408 0.959 rs10821247 chr9:96645864 G/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs8180040 0.654 rs11714373 chr3:47214817 G/A cg27129171 chr3:47204927 SETD2 -0.69 -8.12 -0.59 3.88e-13 Colorectal cancer; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg02953382 chr22:24373134 LOC391322 0.77 7.12 0.54 7.61e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg02073558 chr3:44770973 ZNF501 0.73 7.31 0.55 2.81e-11 Depressive symptoms; TGCT cis rs806215 0.547 rs1419967 chr7:127474435 G/C cg11539674 chr7:127291444 SND1 -0.36 -4.6 -0.38 1.02e-5 Type 2 diabetes; TGCT cis rs17102423 0.530 rs4902359 chr14:65542790 G/A cg11161011 chr14:65562177 MAX -0.47 -6.4 -0.5 2.92e-9 Obesity-related traits; TGCT cis rs7698623 0.717 rs1463094 chr4:88792584 G/A cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs151997 0.853 rs3846498 chr5:50253625 A/C cg06027927 chr5:50259733 NA -0.59 -6.38 -0.5 3.21e-9 Callous-unemotional behaviour; TGCT cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg17264618 chr3:40429014 ENTPD3 0.31 4.59 0.38 1.09e-5 Renal cell carcinoma; TGCT cis rs2243480 0.708 rs35825036 chr7:65986502 T/C cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs5750830 0.649 rs5750808 chr22:39790987 G/A cg02038168 chr22:39784481 NA -0.73 -6.0 -0.47 2.05e-8 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.507 rs10227709 chr7:1180515 T/G cg03188948 chr7:1209495 NA 0.48 4.65 0.39 8.44e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2243480 0.901 rs2456483 chr7:65461575 T/C cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs6424115 0.830 rs2501424 chr1:24199182 T/C cg15997130 chr1:24165203 NA 0.87 9.53 0.65 1.79e-16 Immature fraction of reticulocytes; TGCT cis rs523522 0.962 rs2235218 chr12:120888619 A/C cg27279351 chr12:120934652 DYNLL1 0.74 6.4 0.5 2.95e-9 High light scatter reticulocyte count; TGCT cis rs10464366 0.746 rs34792397 chr7:39146331 G/A cg15212455 chr7:39170539 POU6F2 0.26 5.63 0.45 1.15e-7 IgG glycosylation; TGCT cis rs6840360 0.593 rs6857073 chr4:152689274 A/G cg22705602 chr4:152727874 NA 0.35 5.89 0.47 3.36e-8 Intelligence (multi-trait analysis); TGCT cis rs9969804 0.818 rs10992439 chr9:95495134 T/A cg13940029 chr9:95239186 CENPP;ASPN -0.17 -4.51 -0.38 1.47e-5 Height; TGCT cis rs7178572 0.568 rs12910480 chr15:77664212 G/C cg22256960 chr15:77711686 NA -0.87 -9.0 -0.63 3.34e-15 Type 2 diabetes; TGCT cis rs79349575 0.691 rs28528789 chr17:46986616 C/T cg26022315 chr17:47021804 SNF8 -0.54 -5.37 -0.43 3.73e-7 Type 2 diabetes; TGCT cis rs303386 0.501 rs4908303 chr1:99583230 C/T cg03593336 chr1:99471295 LPPR5 -0.28 -6.01 -0.47 1.91e-8 Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors);Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin); TGCT cis rs362272 0.545 rs3135145 chr4:3299504 T/C cg06533319 chr4:3265114 C4orf44 -0.28 -5.52 -0.44 1.94e-7 Serum sulfate level; TGCT cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs4845570 0.831 rs11588258 chr1:151780728 A/T cg07092448 chr1:151763213 TDRKH -1.17 -8.37 -0.6 1e-13 Coronary artery disease; TGCT cis rs9894429 0.646 rs7405870 chr17:79617284 G/A cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs4642101 0.511 rs9809596 chr3:12840513 C/G cg05775895 chr3:12838266 CAND2 0.83 9.36 0.64 4.36e-16 QRS complex (12-leadsum); TGCT cis rs5750830 0.594 rs9611165 chr22:39775250 A/G cg24399712 chr22:39784796 NA -0.95 -11.01 -0.7 4.37e-20 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.844 rs13223792 chr7:99675659 T/G cg13334819 chr7:99746414 C7orf59 -0.79 -6.87 -0.53 2.73e-10 Coronary artery disease; TGCT cis rs35306767 0.904 rs10904584 chr10:983747 A/T cg26597838 chr10:835615 NA 0.56 7.61 0.56 5.93e-12 Eosinophil percentage of granulocytes; TGCT cis rs7918232 0.943 rs4747584 chr10:27373333 G/A cg14442939 chr10:27389572 ANKRD26 0.73 5.37 0.43 3.69e-7 Breast cancer; TGCT cis rs9611519 0.780 rs1983631 chr22:41644074 C/T cg03806693 chr22:41940476 POLR3H -0.73 -6.79 -0.52 4.19e-10 Neuroticism; TGCT cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg04944784 chr2:26401820 FAM59B -0.72 -5.92 -0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg17747265 chr1:1875780 NA -0.39 -7.23 -0.54 4.33e-11 Body mass index; TGCT cis rs7666738 0.888 rs13110683 chr4:98983368 G/C cg17366294 chr4:99064904 C4orf37 0.77 7.0 0.53 1.4e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7119 0.678 rs12914098 chr15:77823013 C/T cg27398640 chr15:77910606 LINGO1 -0.26 -4.66 -0.39 7.98e-6 Type 2 diabetes; TGCT cis rs7666738 0.830 rs13119913 chr4:98977983 G/T cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs7959452 0.535 rs10878953 chr12:69674187 A/G cg14784868 chr12:69753453 YEATS4 0.69 7.06 0.54 1.04e-10 Blood protein levels; TGCT cis rs910316 1.000 rs2268617 chr14:75608728 G/A cg08847533 chr14:75593920 NEK9 0.95 10.55 0.69 5.78e-19 Height; TGCT cis rs2115630 0.936 rs6496318 chr15:85215229 C/T cg11189052 chr15:85197271 WDR73 -0.67 -6.67 -0.51 7.74e-10 P wave terminal force; TGCT cis rs28595532 1.000 rs56000725 chr4:119637675 G/A cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg04944784 chr2:26401820 FAM59B -0.76 -6.45 -0.5 2.29e-9 Gut microbiome composition (summer); TGCT cis rs919433 0.713 rs1455653 chr2:198478320 G/A cg00792783 chr2:198669748 PLCL1 0.5 4.67 0.39 7.84e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT trans rs7819412 0.745 rs7017567 chr8:10933699 T/A cg06636001 chr8:8085503 FLJ10661 -0.77 -7.04 -0.53 1.16e-10 Triglycerides; TGCT cis rs9611565 0.572 rs139569 chr22:42211141 A/G cg06634786 chr22:41940651 POLR3H -0.78 -7.31 -0.55 2.93e-11 Vitiligo; TGCT cis rs7439150 1.000 rs72681206 chr4:155478278 A/G cg22130008 chr4:155548532 NA -0.44 -5.59 -0.45 1.36e-7 Fibrinogen levels; TGCT cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg03264133 chr6:25882463 NA -0.62 -5.71 -0.46 7.72e-8 Intelligence (multi-trait analysis); TGCT cis rs9948 0.521 rs61750875 chr2:97359364 A/G cg01990225 chr2:97406019 LMAN2L -0.94 -5.3 -0.43 5.2e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs11779988 0.545 rs439374 chr8:17786818 C/T cg01800426 chr8:17659068 MTUS1 -0.64 -5.17 -0.42 9.04e-7 Breast cancer; TGCT cis rs2836950 0.762 rs8134638 chr21:40644170 T/C cg11890956 chr21:40555474 PSMG1 -0.64 -6.02 -0.48 1.81e-8 Menarche (age at onset); TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg09333631 chr3:44802604 KIF15;KIAA1143 -0.42 -4.57 -0.38 1.17e-5 Depressive symptoms; TGCT cis rs60012524 1 rs60012524 chr2:99559117 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.74 -5.45 -0.44 2.57e-7 Chronic sinus infection; TGCT cis rs10479542 0.929 rs7718673 chr5:178980009 C/T cg09060608 chr5:178986726 RUFY1 -0.48 -5.29 -0.43 5.38e-7 Lung cancer; TGCT cis rs75686122 0.892 rs12676448 chr8:104479217 A/G cg04852977 chr8:104510831 NA -0.65 -4.8 -0.4 4.53e-6 Cocaine dependence; TGCT cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg13607699 chr17:42295918 UBTF 0.6 5.48 0.44 2.29e-7 Total body bone mineral density; TGCT cis rs793571 0.544 rs12912699 chr15:58917021 T/C cg05156742 chr15:59063176 FAM63B 0.56 5.34 0.43 4.21e-7 Schizophrenia; TGCT cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg08219700 chr8:58056026 NA 0.38 4.61 0.38 1e-5 Developmental language disorder (linguistic errors); TGCT cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg03709012 chr19:19516395 GATAD2A -0.66 -5.69 -0.46 8.62e-8 Tonsillectomy; TGCT cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg07061783 chr6:25882402 NA -0.63 -6.68 -0.51 7.27e-10 Blood metabolite levels; TGCT cis rs9650657 0.644 rs10091386 chr8:10696620 A/C cg16664915 chr8:10907788 XKR6 -0.29 -4.71 -0.39 6.47e-6 Neuroticism; TGCT cis rs7829975 0.564 rs2921057 chr8:8318667 C/T cg15556689 chr8:8085844 FLJ10661 0.65 6.02 0.48 1.87e-8 Mood instability; TGCT cis rs12220238 0.554 rs10824192 chr10:76251573 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 5.75 0.46 6.45e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT trans rs6089829 0.889 rs6122348 chr20:61663921 C/T cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs881375 0.967 rs2109896 chr9:123683106 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.38 4.52 0.38 1.45e-5 Rheumatoid arthritis; TGCT cis rs600550 0.963 rs657928 chr11:59988906 G/A cg18570331 chr11:60101691 MS4A6E 0.51 4.64 0.38 8.87e-6 Lipoprotein-associated phospholipase A2 activity and mass; TGCT cis rs250677 0.958 rs36068 chr5:148417512 C/T cg18129178 chr5:148520854 ABLIM3 -0.4 -5.63 -0.45 1.17e-7 Breast cancer; TGCT cis rs6931421 1.000 rs6931421 chr6:80880138 A/C cg08355045 chr6:80787529 NA 0.3 4.77 0.39 5.09e-6 Sitting height ratio; TGCT cis rs2288884 0.943 rs12611112 chr19:52574939 G/A cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs11190604 1.000 rs9419897 chr10:102246125 T/C cg23241863 chr10:102295624 HIF1AN 0.64 5.04 0.41 1.59e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6909279 0.933 rs7753676 chr6:151876815 G/A cg14416726 chr6:151773293 C6orf211;RMND1 0.51 4.47 0.37 1.75e-5 Bone mineral density; TGCT cis rs11105306 1 rs11105306 chr12:89897388 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 NT-proBNP levels in acute coronary syndrome; TGCT cis rs7246657 0.722 rs2909100 chr19:38212680 C/T cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs6754311 0.773 rs309180 chr2:136614255 A/G cg07169764 chr2:136633963 MCM6 0.63 5.91 0.47 3.13e-8 Mosquito bite size; TGCT cis rs2952156 0.684 rs881844 chr17:37810218 C/G cg00129232 chr17:37814104 STARD3 -0.22 -4.5 -0.37 1.56e-5 Asthma; TGCT trans rs1814175 0.817 rs28544182 chr11:50049577 G/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs425277 0.527 rs3107144 chr1:2045380 C/A cg24578937 chr1:2090814 PRKCZ -0.23 -5.54 -0.45 1.73e-7 Height; TGCT cis rs12497850 0.931 rs12493289 chr3:48905161 G/A cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs4824093 0.535 rs73443931 chr22:50291603 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.48 4.93 0.41 2.53e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs61990749 0.597 rs13379065 chr14:78141295 C/A cg02301378 chr14:78227641 SNW1;C14orf178 -0.63 -4.62 -0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg12419862 chr22:24373484 LOC391322 0.87 7.67 0.57 4.33e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs78487399 0.808 rs111783562 chr2:43759381 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.8 4.93 0.41 2.54e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs7552404 0.924 rs1498317 chr1:76171984 A/C cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs185694 0.948 rs200512 chr13:30906446 C/T cg07600127 chr13:30881527 KATNAL1 -0.81 -6.52 -0.51 1.6e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs2243480 1.000 rs4149468 chr7:65825690 T/C cg18252515 chr7:66147081 NA -1.22 -7.33 -0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs56104184 0.775 rs56146968 chr19:49398847 A/G cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs1878931 0.597 rs37816 chr16:3456371 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.71 -5.53 -0.44 1.83e-7 Body mass index (adult); TGCT trans rs7726839 0.574 rs11739866 chr5:636299 C/T cg11887960 chr12:57824829 NA 1.14 9.28 0.64 6.87e-16 Obesity-related traits; TGCT cis rs425277 0.958 rs262687 chr1:2117155 G/A cg24578937 chr1:2090814 PRKCZ 0.31 7.81 0.57 2.09e-12 Height; TGCT cis rs826838 0.868 rs864324 chr12:39122853 A/G cg26384229 chr12:38710491 ALG10B 0.82 7.52 0.56 9.37e-12 Heart rate; TGCT cis rs739401 0.572 rs389285 chr11:3062673 G/A cg05729581 chr11:3078854 CARS -0.57 -5.34 -0.43 4.35e-7 Longevity; TGCT cis rs11107903 1.000 rs4762172 chr12:95493912 T/C cg10621809 chr12:95840313 NA 0.68 4.54 0.38 1.3e-5 Coronary artery disease; TGCT cis rs79349575 0.783 rs9747646 chr17:47016882 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs2180341 0.960 rs9401953 chr6:127687574 G/A cg24812749 chr6:127587940 RNF146 0.92 7.43 0.55 1.55e-11 Breast cancer; TGCT trans rs561341 0.941 rs2428336 chr17:30290577 T/C cg20587970 chr11:113659929 NA -1.03 -10.74 -0.69 1.99e-19 Hip circumference adjusted for BMI; TGCT cis rs7208859 0.623 rs8079891 chr17:29058863 G/A cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2249625 0.545 rs55681410 chr6:72877859 G/A cg08500200 chr6:72892038 RIMS1 0.43 4.61 0.38 1e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs9467711 0.606 rs9393710 chr6:26367833 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9807989 0.507 rs4851571 chr2:103019000 C/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs3820068 0.608 rs12734937 chr1:16047726 T/C cg05660106 chr1:15850417 CASP9 0.73 6.78 0.52 4.44e-10 Systolic blood pressure; TGCT cis rs2980436 1 rs2980436 chr8:8092025 A/G cg08975724 chr8:8085496 FLJ10661 -0.61 -5.91 -0.47 3.07e-8 Schizophrenia; TGCT cis rs13223928 0.572 rs12538887 chr7:3134821 G/A cg19214707 chr7:3157722 NA -0.48 -6.9 -0.53 2.42e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs854765 0.647 rs854817 chr17:18021882 T/C cg04398451 chr17:18023971 MYO15A -0.39 -6.81 -0.52 3.78e-10 Total body bone mineral density; TGCT cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg00290607 chr11:67383545 NA 0.29 4.76 0.39 5.31e-6 Mean corpuscular volume; TGCT cis rs6089584 0.566 rs55881457 chr20:60608424 G/A cg13770153 chr20:60521292 NA -0.39 -4.77 -0.39 5.17e-6 Body mass index; TGCT trans rs28595532 0.702 rs72670256 chr4:119391043 G/A cg26518628 chr1:97050305 NA -0.54 -6.79 -0.52 4.14e-10 Cannabis dependence symptom count; TGCT cis rs9894429 0.646 rs6565612 chr17:79602820 C/T cg18240062 chr17:79603768 NPLOC4 -0.54 -4.7 -0.39 6.71e-6 Eye color traits; TGCT cis rs7772486 0.790 rs2254257 chr6:146203724 C/T cg05347473 chr6:146136440 FBXO30 0.53 5.08 0.42 1.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.759 rs62128394 chr2:26364026 T/G cg22920501 chr2:26401640 FAM59B 0.72 5.27 0.43 5.77e-7 Gut microbiome composition (summer); TGCT cis rs10875595 0.836 rs57396973 chr5:140659106 T/A cg20560182 chr5:140700478 TAF7 -0.66 -5.06 -0.41 1.49e-6 Pulmonary function decline; TGCT cis rs2239547 0.522 rs9831409 chr3:52985711 A/T cg11645453 chr3:52864694 ITIH4 -0.32 -5.32 -0.43 4.67e-7 Schizophrenia; TGCT cis rs568617 0.903 rs601863 chr11:65646557 C/A cg04055107 chr11:65626734 MUS81;CFL1 -0.57 -5.22 -0.42 7.39e-7 Crohn's disease; TGCT cis rs7666738 0.546 rs10461174 chr4:98698293 G/A cg17366294 chr4:99064904 C4orf37 0.62 5.77 0.46 6.03e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7945705 0.719 rs2012680 chr11:8996059 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -4.97 -0.41 2.16e-6 Hemoglobin concentration; TGCT cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg17054783 chr10:134559939 INPP5A 0.26 5.3 0.43 5.04e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs603424 0.554 rs10786586 chr10:102087962 A/G cg22671421 chr10:102507979 PAX2 0.54 4.78 0.39 4.95e-6 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs12048904 0.619 rs10875347 chr1:101333737 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.67 5.57 0.45 1.52e-7 Multiple sclerosis; TGCT cis rs459571 0.796 rs10993894 chr9:136884511 C/T cg13789015 chr9:136890014 NCRNA00094 0.4 7.22 0.54 4.48e-11 Platelet distribution width; TGCT cis rs7572733 0.534 rs2060488 chr2:198751637 T/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs854765 0.551 rs8070748 chr17:17859421 A/G cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs7666738 0.830 rs991169 chr4:98928567 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs8056742 0.818 rs870149 chr16:85096556 T/C cg00229868 chr16:85520891 NA 0.34 4.94 0.41 2.47e-6 Amyotrophic lateral sclerosis; TGCT cis rs1153858 1.000 rs9783731 chr15:45642884 C/T cg26924012 chr15:45694286 SPATA5L1 -1.07 -14.56 -0.79 1.32e-28 Homoarginine levels; TGCT cis rs4699052 0.662 rs6848593 chr4:104250113 G/T cg16532752 chr4:104119610 CENPE -0.49 -4.89 -0.4 3.07e-6 Testicular germ cell tumor; TGCT cis rs72781680 0.898 rs72782137 chr2:24047805 C/T cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs8077889 0.956 rs116979403 chr17:41849105 G/A cg26893861 chr17:41843967 DUSP3 1.08 13.16 0.76 2.76e-25 Triglycerides; TGCT cis rs7666738 0.791 rs10033994 chr4:98969582 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs782590 0.807 rs782642 chr2:55928444 G/T cg03859395 chr2:55845619 SMEK2 0.81 8.93 0.63 4.9e-15 Metabolic syndrome; TGCT cis rs1669338 0.588 rs62228620 chr3:3184913 C/T cg16797762 chr3:3221439 CRBN -0.83 -5.24 -0.43 6.58e-7 White matter integrity; TGCT cis rs4888262 0.508 rs6564153 chr16:74658723 A/C cg01733217 chr16:74700730 RFWD3 0.73 6.92 0.53 2.14e-10 Testicular germ cell tumor; TGCT cis rs1797081 0.542 rs2603796 chr10:16871456 C/T cg23933602 chr10:16859644 RSU1 0.73 7.55 0.56 8.37e-12 Platelet distribution width; TGCT cis rs2239547 0.563 rs6445547 chr3:52908577 T/C cg10802521 chr3:52805072 NEK4 -0.58 -5.46 -0.44 2.53e-7 Schizophrenia; TGCT cis rs4805272 0.539 rs1075733 chr19:29324460 C/T cg14983838 chr19:29218262 NA 0.69 4.7 0.39 6.67e-6 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs6923462 0.735 rs13216391 chr6:7789943 A/G cg16988958 chr6:7987739 MGC26597 0.24 4.55 0.38 1.28e-5 Lung function (forced vital capacity); TGCT cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg12042659 chr19:58951599 ZNF132 0.52 4.67 0.39 7.67e-6 Uric acid clearance; TGCT cis rs6540559 0.673 rs7550857 chr1:209956542 C/A cg04352962 chr1:209979756 IRF6 0.65 4.52 0.38 1.42e-5 Cleft lip with or without cleft palate; TGCT cis rs11642862 1.000 rs11642603 chr16:30886221 C/G cg02466173 chr16:30829666 NA -0.4 -4.64 -0.38 8.82e-6 Tonsillectomy; TGCT cis rs2688608 0.618 rs28718766 chr10:75489844 C/A cg04320760 chr10:75533139 FUT11 -0.39 -6.01 -0.48 1.89e-8 Inflammatory bowel disease; TGCT cis rs4819052 0.851 rs2330011 chr21:46658498 G/A cg06618935 chr21:46677482 NA -0.34 -5.29 -0.43 5.29e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12908161 0.959 rs62019472 chr15:85331493 A/G cg12863693 chr15:85201151 NMB 0.42 4.95 0.41 2.38e-6 Schizophrenia; TGCT cis rs6964587 0.869 rs55811257 chr7:91484799 T/A cg17063962 chr7:91808500 NA -0.85 -8.94 -0.63 4.52e-15 Breast cancer; TGCT cis rs17270561 0.666 rs4712976 chr6:25842203 C/T cg17042849 chr6:26104293 HIST1H4C -0.59 -4.52 -0.38 1.45e-5 Iron status biomarkers; TGCT cis rs4523957 0.583 rs8067895 chr17:2030234 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.57 -0.38 1.17e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2439831 0.850 rs28707214 chr15:44131623 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs12142240 0.959 rs12137934 chr1:46728913 A/G cg00530320 chr1:46809349 NSUN4 0.24 4.63 0.38 9.02e-6 Menopause (age at onset); TGCT trans rs17684571 1.000 rs5024547 chr6:56563093 G/A cg14229071 chr15:89282588 NA 0.52 6.82 0.52 3.54e-10 Schizophrenia; TGCT cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Cannabis dependence symptom count; TGCT cis rs4665809 0.652 rs6728090 chr2:26524726 C/T cg04944784 chr2:26401820 FAM59B -0.7 -5.66 -0.45 9.98e-8 Gut microbiome composition (summer); TGCT cis rs3749237 0.595 rs4855839 chr3:49507847 G/A cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs6964587 1.000 rs7791138 chr7:91686789 A/G cg17063962 chr7:91808500 NA 0.88 9.63 0.65 9.8e-17 Breast cancer; TGCT cis rs9611519 0.808 rs5751074 chr22:41665722 G/A cg13695892 chr22:41940480 POLR3H -0.64 -6.08 -0.48 1.39e-8 Neuroticism; TGCT cis rs6733301 0.529 rs2196792 chr2:25259953 A/G cg01884057 chr2:25150051 NA -0.27 -4.62 -0.38 9.61e-6 Height; TGCT cis rs7917772 0.545 rs3934960 chr10:104355275 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.46 -0.44 2.51e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs36051895 0.632 rs10974983 chr9:5149657 G/T cg02405213 chr9:5042618 JAK2 -0.7 -8.84 -0.62 8.02e-15 Pediatric autoimmune diseases; TGCT cis rs6547741 0.935 rs6761095 chr2:27778010 G/T cg27432699 chr2:27873401 GPN1 0.19 4.7 0.39 6.92e-6 Oral cavity cancer; TGCT cis rs9308731 0.644 rs1837368 chr2:111874508 T/C cg04202892 chr2:111875749 ACOXL 0.55 6.24 0.49 6.3e-9 Chronic lymphocytic leukemia; TGCT cis rs1215050 0.740 rs2695464 chr4:98980929 T/C cg17366294 chr4:99064904 C4orf37 -0.55 -5.8 -0.46 5.23e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs644799 0.622 rs1255167 chr11:95500213 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.6 6.23 0.49 6.59e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10504229 1.000 rs10504229 chr8:58196495 A/G cg22535103 chr8:58192502 C8orf71 -0.39 -4.55 -0.38 1.24e-5 Developmental language disorder (linguistic errors); TGCT cis rs7833790 0.654 rs6415652 chr8:82702257 G/A cg06027949 chr8:82754900 SNX16 -0.65 -4.92 -0.4 2.65e-6 Diastolic blood pressure; TGCT cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg20203395 chr5:56204925 C5orf35 0.78 6.15 0.48 9.89e-9 Initial pursuit acceleration; TGCT trans rs7864133 1.000 rs11139265 chr9:84073624 T/C cg23451063 chr7:1059876 C7orf50 0.53 6.71 0.52 6.31e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs6933660 0.760 rs6904364 chr6:151754273 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.83 -8.66 -0.61 2.09e-14 Menarche (age at onset); TGCT cis rs116095464 0.681 rs10060016 chr5:241100 T/C cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs17826219 0.500 rs2449749 chr17:29078298 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs1729951 0.575 rs361242 chr3:136698330 C/G cg21827317 chr3:136751795 NA 0.4 5.6 0.45 1.28e-7 Neuroticism; TGCT cis rs4665809 1.000 rs1550382 chr2:26266877 T/G cg22920501 chr2:26401640 FAM59B -0.72 -6.22 -0.49 7.14e-9 Gut microbiome composition (summer); TGCT cis rs7829975 0.659 rs4382480 chr8:8721473 C/T cg06636001 chr8:8085503 FLJ10661 0.7 6.68 0.51 7.11e-10 Mood instability; TGCT cis rs7635838 0.684 rs2594968 chr3:11352442 T/C cg00170343 chr3:11313890 ATG7 0.6 5.86 0.47 3.84e-8 HDL cholesterol; TGCT cis rs74181299 0.927 rs2723064 chr2:65279805 T/C cg05010058 chr2:65284262 CEP68 0.44 4.93 0.4 2.55e-6 Pulse pressure; TGCT cis rs78487399 0.731 rs6722104 chr2:43752346 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.78 4.84 0.4 3.8e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12579753 0.879 rs1922552 chr12:82158093 G/T cg07988820 chr12:82153109 PPFIA2 -0.67 -7.44 -0.56 1.46e-11 Resting heart rate; TGCT cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.83 -9.98 -0.67 1.38e-17 Urate levels; TGCT cis rs939658 0.935 rs12903747 chr15:79449627 A/C cg17916960 chr15:79447300 NA 0.56 8.87 0.62 6.75e-15 Refractive error; TGCT cis rs1008375 1.000 rs10027755 chr4:17615954 G/C cg16339924 chr4:17578868 LAP3 0.6 4.97 0.41 2.14e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs34526934 0.566 rs1374325 chr2:177043971 G/A cg14324370 chr2:177042789 NA -0.91 -8.69 -0.62 1.8e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs13217239 0.646 rs10456352 chr6:26990358 A/T cg02458000 chr6:26745757 NA 0.51 4.72 0.39 6.22e-6 Schizophrenia; TGCT cis rs9389248 0.690 rs6569982 chr6:135256495 C/G cg22676075 chr6:135203613 NA 0.49 4.81 0.4 4.31e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs7267979 1.000 rs7267979 chr20:25298087 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4820539 1.000 rs885963 chr22:23460939 G/T cg14186256 chr22:23484241 RTDR1 0.97 11.66 0.72 1.16e-21 Bone mineral density; TGCT cis rs4808199 1.000 rs12972397 chr19:19562349 G/A cg03709012 chr19:19516395 GATAD2A 0.97 7.52 0.56 9.52e-12 Nonalcoholic fatty liver disease; TGCT cis rs7949030 0.590 rs12225213 chr11:62350248 T/A cg11742103 chr11:62369870 EML3;MTA2 0.61 8.69 0.62 1.79e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6570726 0.738 rs6925594 chr6:145898454 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1729951 0.575 rs35289288 chr3:136680568 C/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs7216064 1.000 rs4271626 chr17:65930133 G/A cg12091567 chr17:66097778 LOC651250 -0.81 -6.15 -0.48 9.71e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6978712 1.000 rs7789737 chr7:127150683 A/G cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs2153535 0.580 rs6905242 chr6:8471799 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.73 0.46 7.1e-8 Motion sickness; TGCT cis rs3008870 1.000 rs2985818 chr1:67398916 G/A cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.97 0.73 2.07e-22 Lymphocyte percentage of white cells; TGCT cis rs919433 0.713 rs6719729 chr2:198480072 G/A cg00792783 chr2:198669748 PLCL1 0.49 4.56 0.38 1.19e-5 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs2486288 0.656 rs2271438 chr15:45557468 A/G cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.34 -0.43 4.26e-7 Glomerular filtration rate; TGCT cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg18230493 chr5:56204884 C5orf35 -0.67 -5.88 -0.47 3.5e-8 Initial pursuit acceleration; TGCT cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg17971929 chr21:40555470 PSMG1 -0.68 -5.96 -0.47 2.47e-8 Cognitive function; TGCT cis rs6940638 0.956 rs3922717 chr6:27030924 A/G cg26531700 chr6:26746687 NA -0.6 -4.63 -0.38 9.25e-6 Intelligence (multi-trait analysis); TGCT cis rs10193935 0.901 rs2374429 chr2:42677888 A/G cg27598129 chr2:42591480 NA -0.37 -5.14 -0.42 1.04e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9653442 0.545 rs13032454 chr2:100756009 T/C cg22139774 chr2:100720529 AFF3 -0.36 -5.56 -0.45 1.55e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6748734 0.739 rs10185785 chr2:241843752 A/G cg04034577 chr2:241836375 C2orf54 -0.39 -5.64 -0.45 1.09e-7 Urinary metabolites; TGCT cis rs4299518 0.504 rs2673052 chr3:45733827 A/T cg04837898 chr3:45731254 SACM1L -0.55 -5.55 -0.45 1.64e-7 Hirschsprung disease; TGCT cis rs6866344 0.601 rs4419608 chr5:178097049 C/T cg10224037 chr5:178157518 ZNF354A 0.58 5.07 0.41 1.4e-6 Neutrophil percentage of white cells; TGCT cis rs6586111 1.000 rs4933462 chr10:82372612 A/G cg03086067 chr10:82368399 SH2D4B -0.26 -5.17 -0.42 9.28e-7 Capecitabine sensitivity; TGCT cis rs7829975 0.807 rs519019 chr8:8595104 A/T cg06636001 chr8:8085503 FLJ10661 -0.57 -4.72 -0.39 6.16e-6 Mood instability; TGCT cis rs6543140 0.964 rs10193485 chr2:103089573 T/C cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs2361718 0.500 rs8068856 chr17:78100731 A/G cg17882374 chr17:78041429 CCDC40 0.29 4.49 0.37 1.6e-5 Yeast infection; TGCT cis rs12220238 0.659 rs10824208 chr10:76357634 A/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 5.75 0.46 6.45e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs11992186 0.597 rs77717027 chr8:8591632 T/C cg06636001 chr8:8085503 FLJ10661 -0.59 -4.9 -0.4 2.91e-6 Neuroticism; TGCT cis rs7666738 0.546 rs17546687 chr4:98769266 T/A cg18180107 chr4:99064573 C4orf37 0.53 4.62 0.38 9.51e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8049040 0.644 rs16973000 chr16:71493165 T/C cg06353428 chr16:71660113 MARVELD3 -0.66 -5.24 -0.43 6.71e-7 Blood protein levels; TGCT cis rs1635 0.655 rs58019071 chr6:28304016 T/C cg15743358 chr6:28303923 ZNF323 -1.28 -6.27 -0.49 5.57e-9 Schizophrenia; TGCT cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs7091068 0.518 rs913045 chr10:95431535 C/T cg20715218 chr10:95462985 C10orf4 0.52 5.56 0.45 1.59e-7 Urinary tract infection frequency; TGCT cis rs12544026 0.581 rs519197 chr8:102860675 C/A cg01952226 chr8:102507382 GRHL2 -0.27 -4.54 -0.38 1.31e-5 Major depression and alcohol dependence; TGCT trans rs916888 0.773 rs538628 chr17:44787313 G/C cg22968622 chr17:43663579 NA 1.29 11.02 0.7 4.06e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 0.679 rs60869047 chr8:58053221 G/A cg08280861 chr8:58055591 NA 0.35 4.88 0.4 3.2e-6 Developmental language disorder (linguistic errors); TGCT cis rs9926296 0.744 rs154657 chr16:89708096 A/G cg01097406 chr16:89675127 NA -0.35 -6.31 -0.49 4.55e-9 Vitiligo; TGCT trans rs783396 0.584 rs783414 chr6:106966701 A/G cg09013229 chr1:225332226 DNAH14 -0.53 -6.66 -0.51 8.13e-10 Stroke; TGCT cis rs68170813 0.570 rs7794915 chr7:106849393 C/T cg02696742 chr7:106810147 HBP1 -0.66 -4.7 -0.39 6.66e-6 Coronary artery disease; TGCT cis rs763014 0.931 rs7191939 chr16:630089 C/T cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs2439831 0.764 rs2447193 chr15:43929733 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.73 4.95 0.41 2.38e-6 Lung cancer in ever smokers; TGCT cis rs911555 0.928 rs911554 chr14:103999371 G/T cg12935359 chr14:103987150 CKB 0.35 4.94 0.41 2.49e-6 Intelligence (multi-trait analysis); TGCT cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs769267 0.965 rs1469712 chr19:19528821 C/A cg08509172 chr19:19383838 TM6SF2 -0.35 -4.63 -0.38 9.18e-6 Tonsillectomy; TGCT cis rs951366 0.873 rs823118 chr1:205723572 C/T cg07167872 chr1:205819463 PM20D1 0.41 4.77 0.39 5.15e-6 Menarche (age at onset); TGCT cis rs7267979 0.966 rs6083855 chr20:25405118 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6690583 0.562 rs12024977 chr1:85531051 A/C cg20280350 chr1:85513789 MCOLN3 -0.74 -4.66 -0.39 7.96e-6 Serum sulfate level; TGCT cis rs7552404 1.000 rs7516226 chr1:76234257 G/A cg10523679 chr1:76189770 ACADM 0.91 9.53 0.65 1.7e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs8180040 0.966 rs13059519 chr3:47539969 C/T cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs2228479 0.850 rs17226519 chr16:89839854 T/C cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg01802117 chr1:53393560 SCP2 -0.39 -4.7 -0.39 6.93e-6 Monocyte count; TGCT cis rs4409675 0.576 rs7535816 chr1:28234054 A/G cg23691781 chr1:28212827 C1orf38 0.26 5.51 0.44 2.01e-7 Corneal astigmatism; TGCT cis rs7666738 0.822 rs979946 chr4:98921235 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.5 0.56 1.09e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2346177 0.605 rs7556828 chr2:46663172 A/G cg26688816 chr2:46740690 ATP6V1E2 0.43 4.67 0.39 7.59e-6 HDL cholesterol; TGCT cis rs2562456 0.833 rs552800 chr19:21484642 G/A cg25650185 chr19:21324782 ZNF431 0.54 4.52 0.38 1.41e-5 Pain; TGCT cis rs1563304 1 rs1563304 chr17:44874453 C/T cg01570182 chr17:44337453 NA 0.72 4.87 0.4 3.37e-6 Neuroticism; TGCT cis rs13088645 0.683 rs9790169 chr3:134151959 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.63 -6.11 -0.48 1.17e-8 Coronary artery disease; TGCT cis rs28735056 0.903 rs56185453 chr18:77638297 A/G cg20368463 chr18:77673604 PQLC1 -0.44 -5.33 -0.43 4.38e-7 Schizophrenia; TGCT cis rs3824662 0.592 rs263418 chr10:8118191 A/G cg20314737 chr10:8096579 FLJ45983;GATA3 0.64 4.48 0.37 1.64e-5 Acute lymphoblastic leukemia (B-cell precursor);Acute lymphoblastic leukemia (adolescents and young adults); TGCT cis rs13168506 0.538 rs12515040 chr5:135441559 A/G cg00308130 chr5:135415190 NA -0.33 -4.59 -0.38 1.08e-5 Stroke; TGCT cis rs12188164 1.000 rs72717411 chr5:429124 C/G cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.76 -0.39 5.27e-6 Cystic fibrosis severity; TGCT cis rs2905347 0.895 rs2961283 chr7:22640498 A/G cg26061582 chr7:22766209 IL6 0.4 4.49 0.37 1.63e-5 Major depression and alcohol dependence; TGCT cis rs2204008 0.639 rs7311462 chr12:38278130 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs4494114 1.000 rs3790442 chr1:39357646 C/A cg25970120 chr1:39325951 RRAGC -0.6 -6.17 -0.48 8.89e-9 Blood protein levels; TGCT cis rs5769707 0.967 rs763127 chr22:50006078 C/T cg05373962 chr22:49881684 NA -0.31 -6.26 -0.49 5.71e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs174601 0.615 rs174534 chr11:61549458 C/T cg19610905 chr11:61596333 FADS2 0.8 7.91 0.58 1.19e-12 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT trans rs7698623 0.850 rs3886171 chr4:88800053 A/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.61 -0.51 1.01e-9 Cardiovascular disease risk factors; TGCT cis rs7651736 0.835 rs6439679 chr3:136757463 C/T cg21827317 chr3:136751795 NA -0.41 -5.85 -0.46 4.17e-8 Neuroticism; TGCT cis rs782590 0.902 rs7582278 chr2:55742924 C/G cg18811423 chr2:55921094 PNPT1 0.67 7.1 0.54 8.6e-11 Metabolic syndrome; TGCT cis rs548181 0.611 rs562599 chr11:125459951 A/C cg03464685 chr11:125439445 EI24 1.31 9.21 0.64 1.01e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7829975 0.591 rs12677543 chr8:8644274 G/C cg08975724 chr8:8085496 FLJ10661 0.56 4.91 0.4 2.85e-6 Mood instability; TGCT cis rs597539 0.652 rs622082 chr11:68703959 A/G cg21963583 chr11:68658836 MRPL21 0.37 6.08 0.48 1.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4863687 0.752 rs4863507 chr4:140643322 A/G cg10136560 chr4:140737518 MAML3 -0.32 -5.01 -0.41 1.82e-6 Chronic mucus hypersecretion; TGCT cis rs4665809 0.589 rs4665842 chr2:26448954 A/G cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.13 14.76 0.8 4.39e-29 Height; TGCT cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs17376456 0.877 rs10057814 chr5:93399092 C/G cg21475434 chr5:93447410 FAM172A 0.61 4.85 0.4 3.62e-6 Diabetic retinopathy; TGCT cis rs35306767 0.953 rs7908138 chr10:962978 C/T cg20503657 chr10:835505 NA 0.68 9.49 0.65 2.12e-16 Eosinophil percentage of granulocytes; TGCT cis rs4242434 0.672 rs6993302 chr8:22527457 T/C cg03733263 chr8:22462867 KIAA1967 -1.05 -15.55 -0.81 6.67e-31 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs56011263 0.687 rs4690293 chr4:706101 A/G cg17689763 chr4:710664 PCGF3 -0.24 -7.09 -0.54 8.75e-11 White blood cell count; TGCT cis rs2455799 0.573 rs2455834 chr3:15753641 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.77 -0.39 5.01e-6 Mean platelet volume; TGCT cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg00786635 chr1:25594202 NA 0.58 6.04 0.48 1.69e-8 Erythrocyte sedimentation rate; TGCT cis rs6840360 0.593 rs1429559 chr4:152681952 A/G cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.63e-8 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg06238570 chr21:40685208 BRWD1 0.68 6.36 0.5 3.5e-9 Cognitive function; TGCT cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg23205692 chr1:25664452 TMEM50A -0.47 -4.93 -0.4 2.63e-6 Erythrocyte sedimentation rate; TGCT cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg03609598 chr5:56110824 MAP3K1 -0.57 -4.74 -0.39 5.7e-6 Initial pursuit acceleration; TGCT cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs7666738 0.645 rs10013290 chr4:99082799 G/A cg17366294 chr4:99064904 C4orf37 0.71 6.87 0.53 2.73e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs727563 0.638 rs4820443 chr22:42193913 A/G cg03806693 chr22:41940476 POLR3H -0.97 -9.87 -0.66 2.66e-17 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4689388 0.926 rs1801214 chr4:6303022 C/T cg00701064 chr4:6280414 WFS1 0.38 4.85 0.4 3.61e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs921968 0.541 rs642520 chr2:219423605 A/G cg02176678 chr2:219576539 TTLL4 -0.47 -6.81 -0.52 3.72e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7258465 1.000 rs4808804 chr19:18585325 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.6 0.38 1.03e-5 Breast cancer; TGCT cis rs2033711 0.755 rs4801587 chr19:58936679 C/A cg04608855 chr19:58913158 NA 0.57 5.7 0.46 8.22e-8 Uric acid clearance; TGCT cis rs473651 0.935 rs515412 chr2:239345394 A/T cg08773314 chr2:239334832 ASB1 0.45 7.62 0.56 5.75e-12 Multiple system atrophy; TGCT trans rs2688608 0.725 rs2675666 chr10:75682651 G/T cg13918328 chr10:52500089 ASAH2B 0.68 6.93 0.53 1.99e-10 Inflammatory bowel disease; TGCT cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT trans rs208520 0.690 rs207118 chr6:66788948 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs10779751 1.000 rs1064261 chr1:11288758 C/T cg08854313 chr1:11322531 MTOR 1.0 8.95 0.63 4.4e-15 Body mass index; TGCT cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs7312933 0.670 rs10880269 chr12:42606135 C/T cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs10464366 0.614 rs62442213 chr7:39146933 C/T cg18850127 chr7:39170497 POU6F2 0.33 7.5 0.56 1.05e-11 IgG glycosylation; TGCT cis rs2933343 0.951 rs789218 chr3:128592670 G/A cg11901034 chr3:128598214 ACAD9 -0.65 -5.12 -0.42 1.15e-6 IgG glycosylation; TGCT cis rs9611519 0.857 rs4820434 chr22:41637119 G/T cg03806693 chr22:41940476 POLR3H -0.78 -7.71 -0.57 3.49e-12 Neuroticism; TGCT cis rs7666738 0.830 rs62321564 chr4:98976496 C/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2665796 chr17:61923716 G/C cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs6840360 1.000 rs4696283 chr4:152580516 A/G cg17479576 chr4:152424074 FAM160A1 -0.46 -4.81 -0.4 4.26e-6 Intelligence (multi-trait analysis); TGCT cis rs10464366 0.912 rs7785889 chr7:39106368 G/T cg18850127 chr7:39170497 POU6F2 0.21 4.5 0.37 1.55e-5 IgG glycosylation; TGCT cis rs910316 0.737 rs175077 chr14:75506875 G/A cg08847533 chr14:75593920 NEK9 -0.84 -8.43 -0.6 7.53e-14 Height; TGCT cis rs4819052 0.851 rs2838829 chr21:46664040 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10782582 0.593 rs74090712 chr1:76189098 A/G cg03433033 chr1:76189801 ACADM -0.61 -6.76 -0.52 4.85e-10 Daytime sleep phenotypes; TGCT cis rs2404602 0.647 rs12904149 chr15:77043652 A/C cg22467129 chr15:76604101 ETFA 0.47 4.58 0.38 1.13e-5 Blood metabolite levels; TGCT cis rs986417 0.711 rs2224409 chr14:60957216 C/T cg27398547 chr14:60952738 C14orf39 1.41 9.11 0.63 1.75e-15 Gut microbiota (bacterial taxa); TGCT cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs2721195 0.845 rs3816732 chr8:145724275 T/C cg13257436 chr8:145726034 PPP1R16A -0.31 -4.5 -0.37 1.53e-5 Age at first birth; TGCT cis rs1218582 0.772 rs4845682 chr1:154877105 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs7731657 0.510 rs2569257 chr5:130245468 A/G cg08523029 chr5:130500466 HINT1 -0.58 -4.75 -0.39 5.41e-6 Fasting plasma glucose; TGCT cis rs10504229 1.000 rs72652905 chr8:58188355 A/G cg21724239 chr8:58056113 NA 0.37 4.95 0.41 2.38e-6 Developmental language disorder (linguistic errors); TGCT cis rs9911578 1.000 rs8076121 chr17:57041699 G/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs1784581 0.588 rs9295179 chr6:162420546 G/A cg17173639 chr6:162384350 PARK2 0.39 6.5 0.5 1.73e-9 Itch intensity from mosquito bite; TGCT cis rs9457247 0.935 rs1187530 chr6:167376812 C/T cg25258033 chr6:167368657 RNASET2 -0.18 -4.48 -0.37 1.64e-5 Crohn's disease; TGCT cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT trans rs783396 0.584 rs9486400 chr6:107013846 A/C cg09256880 chr4:2791952 NA 0.49 6.77 0.52 4.5e-10 Stroke; TGCT cis rs548987 0.507 rs3757132 chr6:25832691 C/T cg03264133 chr6:25882463 NA -0.54 -4.47 -0.37 1.73e-5 Homocysteine levels; TGCT cis rs1008375 1.000 rs9991307 chr4:17662408 A/G cg10189774 chr4:17578691 LAP3 0.54 4.97 0.41 2.21e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4664308 1.000 rs6719686 chr2:160908292 T/G cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs17376456 0.877 rs10476599 chr5:93383423 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs4319547 0.656 rs28730465 chr12:122863864 A/C cg05707623 chr12:122985044 ZCCHC8 0.62 4.87 0.4 3.32e-6 Body mass index; TGCT cis rs4665809 0.838 rs6546780 chr2:26352857 T/C cg22920501 chr2:26401640 FAM59B -0.71 -6.2 -0.49 7.53e-9 Gut microbiome composition (summer); TGCT cis rs3617 0.573 rs12492391 chr3:52912296 C/A cg11645453 chr3:52864694 ITIH4 0.26 5.05 0.41 1.54e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.790 rs9403756 chr6:146257761 C/G cg13319975 chr6:146136371 FBXO30 0.48 4.5 0.37 1.52e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs669446 0.561 rs571862 chr1:44083110 C/T cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7216064 1.000 rs62084238 chr17:65856573 T/A cg12091567 chr17:66097778 LOC651250 -0.83 -6.52 -0.51 1.61e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2663905 0.706 rs7162859 chr15:81360038 C/T cg27045999 chr15:81426544 C15orf26 0.63 5.63 0.45 1.15e-7 QT interval (drug interaction); TGCT cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs9581857 0.547 rs76435345 chr13:28107638 G/A cg22138327 chr13:27999177 GTF3A 0.72 4.75 0.39 5.45e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7953249 0.618 rs7954039 chr12:121398654 A/C cg02403541 chr12:121454288 C12orf43 -0.65 -5.5 -0.44 2.07e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs2730245 0.527 rs2527197 chr7:158735260 G/A cg11984989 chr7:158649758 WDR60 -1.01 -7.88 -0.58 1.4e-12 Height; TGCT cis rs11098499 0.955 rs11944880 chr4:120159334 A/G cg24670566 chr4:120433619 PDE5A -0.23 -4.45 -0.37 1.89e-5 Corneal astigmatism; TGCT cis rs11650494 0.908 rs11656535 chr17:47425588 C/T cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs66573146 1.000 rs66573146 chr4:6984464 C/G cg01220768 chr4:7056774 TADA2B 0.39 4.91 0.4 2.77e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs76878669 0.561 rs10791876 chr11:66169646 C/T cg18002602 chr11:66138449 SLC29A2 -0.53 -6.5 -0.5 1.74e-9 Educational attainment (years of education); TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg11905131 chr22:24372483 LOC391322 -0.86 -9.98 -0.67 1.38e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs854765 0.583 rs9890341 chr17:17823175 G/C cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.83e-6 Total body bone mineral density; TGCT cis rs826838 0.967 rs4768330 chr12:39129399 T/C cg26384229 chr12:38710491 ALG10B -0.87 -7.78 -0.57 2.42e-12 Heart rate; TGCT trans rs8073060 0.544 rs17550716 chr17:33893208 A/G cg19694781 chr19:47549865 TMEM160 0.59 12.8 0.75 1.95e-24 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7582180 0.627 rs6542947 chr2:100999647 C/G cg08017756 chr2:100939284 LONRF2 0.3 5.0 0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs2228479 0.850 rs62056065 chr16:89905115 C/G cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs28595532 0.748 rs67928655 chr4:119336525 C/A cg21605333 chr4:119757512 SEC24D 0.85 5.43 0.44 2.84e-7 Cannabis dependence symptom count; TGCT trans rs2688608 0.592 rs3933085 chr10:75483331 C/T cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs4888262 0.526 rs8056718 chr16:74612030 G/C cg01733217 chr16:74700730 RFWD3 0.75 7.54 0.56 8.8e-12 Testicular germ cell tumor; TGCT cis rs2797160 0.967 rs4897151 chr6:125993202 T/G cg05901451 chr6:126070800 HEY2 -0.74 -6.49 -0.5 1.84e-9 Endometrial cancer; TGCT cis rs174601 0.668 rs174559 chr11:61581656 G/A cg19610905 chr11:61596333 FADS2 -0.96 -9.3 -0.64 6.26e-16 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs8050907 0.744 rs28629405 chr16:4525933 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs1982963 0.906 rs2029976 chr14:52505811 C/T cg10843707 chr14:52510701 NID2 -0.43 -6.6 -0.51 1.09e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs5750830 0.649 rs4337572 chr22:39800704 C/G cg24399712 chr22:39784796 NA -0.99 -9.19 -0.64 1.15e-15 Intelligence (multi-trait analysis); TGCT cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg05738196 chr6:26577821 NA -0.51 -4.92 -0.4 2.71e-6 Schizophrenia; TGCT cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.85 -9.09 -0.63 2.04e-15 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs115214765 chr4:119728167 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs712888 0.564 rs712902 chr1:99725473 A/G cg02083189 chr1:100503813 HIAT1 -0.54 -4.73 -0.39 5.95e-6 Bacterial meningitis; TGCT cis rs17152411 1.000 rs2241541 chr10:126671673 T/C cg07906193 chr10:126599966 NA 0.41 4.83 0.4 3.97e-6 Height; TGCT cis rs1799949 0.965 rs799917 chr17:41244936 G/A cg23758822 chr17:41437982 NA 0.67 6.74 0.52 5.2400000000000005e-10 Menopause (age at onset); TGCT cis rs6740322 0.895 rs28456986 chr2:43553321 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.72 -0.52 5.98e-10 Coronary artery disease; TGCT cis rs9486715 0.867 rs7451950 chr6:96879974 T/C cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs7698623 0.717 rs4147245 chr4:88779237 A/C cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs1023500 0.573 rs133370 chr22:42465260 T/C cg05082376 chr22:42548792 NA -0.22 -5.41 -0.44 3.18e-7 Schizophrenia; TGCT cis rs4919669 0.668 rs77630251 chr10:104338370 C/G cg05855489 chr10:104503620 C10orf26 0.73 4.71 0.39 6.65e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs1986116 0.773 rs4903538 chr14:77516821 C/T cg04913803 chr14:77510549 NA 0.39 4.62 0.38 9.48e-6 Sleep quality; TGCT cis rs5769765 0.955 rs8135963 chr22:50301476 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.21 0.42 7.51e-7 Schizophrenia; TGCT cis rs3772130 0.962 rs9856641 chr3:121566859 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs2180341 0.889 rs2000909 chr6:127711173 G/A cg27446573 chr6:127587934 RNF146 0.92 8.63 0.61 2.47e-14 Breast cancer; TGCT cis rs9650657 0.535 rs7011756 chr8:11019578 C/G cg21775007 chr8:11205619 TDH -0.53 -5.0 -0.41 1.88e-6 Neuroticism; TGCT cis rs6089584 0.888 rs2892060 chr20:60617955 G/T cg16423285 chr20:60520624 NA -0.61 -6.57 -0.51 1.23e-9 Body mass index; TGCT cis rs868036 0.645 rs4492996 chr15:68113240 A/G cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs7267979 0.966 rs2261795 chr20:25263136 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9409154 0.816 rs10116195 chr9:118212010 T/C cg14094498 chr9:119000864 PAPPA 0.23 4.59 0.38 1.05e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs9926296 0.607 rs11076629 chr16:89875259 T/C cg26513180 chr16:89883248 FANCA 0.74 7.0 0.53 1.4e-10 Vitiligo; TGCT cis rs6896969 0.510 rs1899982 chr5:40425045 C/T cg01087697 chr5:40835557 RPL37 0.56 5.03 0.41 1.69e-6 Multiple sclerosis; TGCT cis rs9948 0.708 rs116121826 chr2:97441914 A/G cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs826838 0.616 rs7977357 chr12:38626008 C/G cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs8111998 0.826 rs4932778 chr19:22766971 G/A cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs12549902 0.932 rs6981607 chr8:41508168 A/C cg00088007 chr8:41504566 NKX6-3 0.34 5.47 0.44 2.33e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs12477438 0.765 rs12468807 chr2:99691994 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs10256972 0.721 rs10435145 chr7:1065988 C/T cg00431813 chr7:1051703 C7orf50 -0.22 -4.9 -0.4 2.93e-6 Longevity;Endometriosis; TGCT cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs1552244 0.816 rs56387520 chr3:10042782 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs478304 0.651 rs11532071 chr11:65500198 C/A cg27068330 chr11:65405492 SIPA1 -0.95 -9.64 -0.65 9.63e-17 Acne (severe); TGCT cis rs7945705 0.791 rs4579928 chr11:8815704 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.44 4.88 0.4 3.17e-6 Hemoglobin concentration; TGCT cis rs9911578 0.935 rs7218105 chr17:57041119 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs35883536 0.647 rs17411209 chr1:101046734 A/G cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs600231 0.665 rs1616810 chr11:65220105 A/G cg17120908 chr11:65337727 SSSCA1 -0.51 -4.6 -0.38 1.02e-5 Bone mineral density; TGCT trans rs28595532 0.660 rs11933762 chr4:119307126 A/G cg26518628 chr1:97050305 NA -0.52 -7.66 -0.57 4.58e-12 Cannabis dependence symptom count; TGCT cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg11502198 chr6:26597334 ABT1 0.55 4.9 0.4 2.92e-6 Intelligence (multi-trait analysis); TGCT cis rs17030434 0.834 rs28658020 chr4:154759048 C/T cg14289246 chr4:154710475 SFRP2 -0.91 -7.82 -0.57 1.98e-12 Electrocardiographic conduction measures; TGCT cis rs1448094 0.717 rs60713909 chr12:86294469 C/G cg00310523 chr12:86230176 RASSF9 0.32 4.62 0.38 9.64e-6 Major depressive disorder; TGCT cis rs12136530 0.577 rs12066114 chr1:19792527 A/G cg18923740 chr1:19971790 NBL1 0.4 4.9 0.4 2.98e-6 Lead levels in blood; TGCT cis rs2486288 0.656 rs8041702 chr15:45547093 C/T cg26924012 chr15:45694286 SPATA5L1 -0.8 -7.91 -0.58 1.24e-12 Glomerular filtration rate; TGCT cis rs6582630 0.638 rs61931383 chr12:38513845 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4494114 0.967 rs7527128 chr1:39302993 C/T cg25970120 chr1:39325951 RRAGC -0.6 -6.28 -0.49 5.09e-9 Blood protein levels; TGCT cis rs4642101 0.793 rs56082700 chr3:12833833 T/C cg05775895 chr3:12838266 CAND2 0.78 8.75 0.62 1.3e-14 QRS complex (12-leadsum); TGCT cis rs4665630 0.522 rs889866 chr2:23885168 A/G cg08063864 chr2:24346004 PFN4;LOC375190 -1.13 -5.45 -0.44 2.64e-7 Hypertension; TGCT cis rs711245 0.574 rs1179494 chr2:36809496 C/G cg01206211 chr2:36825736 FEZ2 -0.32 -4.82 -0.4 4.09e-6 Height; TGCT cis rs3806843 0.735 rs2563333 chr5:140052271 A/G cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 8.95e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4713118 0.955 rs9380011 chr6:27683924 A/G cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT cis rs1577917 0.740 rs9344533 chr6:86236188 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.54 4.87 0.4 3.29e-6 Response to antipsychotic treatment; TGCT cis rs1670533 1.000 rs7685541 chr4:1058501 G/A cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs10992471 0.528 rs10514815 chr9:95256695 C/A cg13798575 chr9:95087839 CENPP;NOL8 -0.5 -4.62 -0.38 9.57e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs11969893 0.737 rs6930051 chr6:101406108 A/G cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs17826219 0.568 rs2626985 chr17:29077437 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs10504229 0.683 rs7000349 chr8:58114569 C/A cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs1878931 0.554 rs3207360 chr16:3498115 G/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.86 7.81 0.57 2.07e-12 Body mass index (adult); TGCT cis rs9611519 0.780 rs9611527 chr22:41644428 G/A cg03806693 chr22:41940476 POLR3H -0.77 -7.41 -0.55 1.72e-11 Neuroticism; TGCT cis rs5744897 0.581 rs35235926 chr12:133304126 G/A cg17341477 chr12:133246679 POLE 0.35 4.65 0.39 8.45e-6 Urate levels in overweight individuals; TGCT cis rs3806933 0.522 rs34962120 chr5:110446091 G/A cg04022379 chr5:110408740 TSLP 0.6 6.25 0.49 6.08e-9 Eosinophilic esophagitis; TGCT cis rs5769707 0.837 rs1573726 chr22:50032872 G/A cg05373962 chr22:49881684 NA -0.28 -5.44 -0.44 2.73e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4919044 0.733 rs12413378 chr10:94759305 A/G cg05127821 chr10:94822908 CYP26C1 -0.82 -4.97 -0.41 2.14e-6 Coronary artery disease; TGCT trans rs751984 0.706 rs10792315 chr11:61274790 T/G cg03305746 chr2:106927199 NA -0.58 -6.8 -0.52 3.93e-10 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs5750830 0.595 rs4821892 chr22:39795683 G/C cg05872129 chr22:39784769 NA -1.01 -11.06 -0.7 3.28e-20 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.800 rs9892675 chr17:37549200 C/T cg07936489 chr17:37558343 FBXL20 0.89 7.38 0.55 1.99e-11 Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.754 rs9991959 chr4:120253773 C/T cg09307838 chr4:120376055 NA -0.61 -5.86 -0.47 3.95e-8 Corneal astigmatism; TGCT cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg04267008 chr7:1944627 MAD1L1 -0.4 -5.35 -0.43 4.15e-7 Bipolar disorder and schizophrenia; TGCT cis rs644799 0.965 rs3789960 chr11:95509037 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.46 0.6 6.27e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7267979 1.000 rs422844 chr20:25445591 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9303542 0.625 rs8066613 chr17:46583520 T/A cg25032089 chr17:46643351 HOXB3 0.57 5.74 0.46 6.78e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6815814 0.950 rs56408159 chr4:38812116 T/A cg02016764 chr4:38805732 TLR1 -0.36 -5.67 -0.45 9.33e-8 Breast cancer; TGCT cis rs7246657 0.943 rs3803895 chr19:37898669 A/G cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg11890956 chr21:40555474 PSMG1 1.11 12.39 0.74 1.95e-23 Cognitive function; TGCT cis rs2458413 0.564 rs2458431 chr8:105367096 T/C cg04554929 chr8:105342491 NA 0.49 5.79 0.46 5.35e-8 Paget's disease; TGCT trans rs11722228 0.521 rs62288520 chr4:10099674 G/A cg26043149 chr18:55253948 FECH 1.16 11.2 0.71 1.55e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs7172809 0.897 rs17394448 chr15:77825149 C/A cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs17767294 0.708 rs72846777 chr6:28114810 C/T cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs422249 0.512 rs174562 chr11:61585144 A/G cg01500311 chr11:61656094 FADS3 -0.3 -5.25 -0.43 6.42e-7 Trans fatty acid levels; TGCT cis rs7095607 0.933 rs12785213 chr10:69964674 G/A cg18986048 chr10:69913749 MYPN 0.45 4.89 0.4 3.07e-6 Lung function (FVC); TGCT cis rs270601 0.739 rs1979981 chr5:131601720 G/A cg12564285 chr5:131593104 PDLIM4 0.4 4.78 0.39 4.79e-6 Acylcarnitine levels; TGCT cis rs1466788 1.000 rs1869596 chr1:110624104 G/A cg11787288 chr1:111506544 C1orf103 0.5 4.48 0.37 1.64e-5 Blood metabolite levels; TGCT cis rs35306767 0.855 rs12774985 chr10:904245 C/T cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs12135062 0.755 rs1553287 chr1:3101277 G/A cg21609526 chr1:3105151 PRDM16 -0.36 -5.73 -0.46 7.25e-8 Migraine; TGCT trans rs7698623 0.850 rs10011586 chr4:88798921 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.61 -0.51 1.01e-9 Cardiovascular disease risk factors; TGCT cis rs6087990 0.765 rs6058900 chr20:31400673 T/C cg09149842 chr20:31351091 DNMT3B -0.36 -4.89 -0.4 3.05e-6 Ulcerative colitis; TGCT cis rs4689388 0.890 rs1801206 chr4:6302707 C/T cg25554036 chr4:6271136 WFS1 0.57 8.25 0.6 1.99e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9303542 0.559 rs56038617 chr17:46612578 C/T cg25032089 chr17:46643351 HOXB3 0.58 5.47 0.44 2.38e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 3.03e-27 Menopause (age at onset); TGCT cis rs9916302 0.706 rs597069 chr17:37458512 G/T cg03321784 chr17:37729644 NA -0.43 -4.46 -0.37 1.84e-5 Glomerular filtration rate (creatinine); TGCT cis rs6546537 1.000 rs6712370 chr2:69855094 C/G cg10773587 chr2:69614142 GFPT1 0.73 6.34 0.49 3.98e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs2204008 0.555 rs7310307 chr12:38107497 G/T cg13010199 chr12:38710504 ALG10B 0.65 5.15 0.42 9.75e-7 Bladder cancer; TGCT cis rs16867321 0.618 rs13400340 chr2:181561429 A/G cg12875548 chr2:181044332 NA -0.38 -4.75 -0.39 5.44e-6 Obesity; TGCT cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg06212747 chr3:49208901 KLHDC8B 0.65 6.08 0.48 1.36e-8 Menarche (age at onset); TGCT cis rs10540 0.915 rs12419209 chr11:494510 T/C cg03352830 chr11:487213 PTDSS2 0.26 4.44 0.37 1.95e-5 Body mass index; TGCT cis rs7607369 0.500 rs6712856 chr2:219658617 A/T cg02176678 chr2:219576539 TTLL4 -0.48 -6.34 -0.49 3.89e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs9942416 0.660 rs17649055 chr5:74984269 C/T cg02573091 chr5:74908125 NA 0.39 4.45 0.37 1.88e-5 Age-related disease endophenotypes; TGCT cis rs1401999 1.000 rs6800217 chr3:183685893 T/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs3782455 1.000 rs16943528 chr12:114403582 A/C cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg09033563 chr22:24373618 LOC391322 0.51 4.98 0.41 2.11e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg08280861 chr8:58055591 NA 0.54 6.1 0.48 1.22e-8 Developmental language disorder (linguistic errors); TGCT cis rs2762353 0.935 rs3757130 chr6:25770866 C/T cg03517284 chr6:25882590 NA 0.49 5.07 0.41 1.42e-6 Blood metabolite levels; TGCT cis rs78487399 0.808 rs10203174 chr2:43690030 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.99 -0.47 2.13e-8 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4727027 0.933 rs1044358 chr7:148879951 C/A cg23583168 chr7:148888333 NA -0.74 -9.81 -0.66 3.64e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs8073060 0.518 rs225285 chr17:33931084 G/C cg19694781 chr19:47549865 TMEM160 -0.44 -8.53 -0.61 4.24e-14 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs4642101 0.793 rs6799179 chr3:12829095 A/C cg05775895 chr3:12838266 CAND2 0.78 8.9 0.62 5.77e-15 QRS complex (12-leadsum); TGCT cis rs7833790 0.963 rs1451997 chr8:82774053 A/T cg23324259 chr8:82754387 SNX16 0.66 4.6 0.38 1.02e-5 Diastolic blood pressure; TGCT cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs9300255 0.568 rs1047158 chr12:123644056 C/A cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg06634786 chr22:41940651 POLR3H -0.89 -8.16 -0.59 3.16e-13 Vitiligo; TGCT cis rs9549367 0.789 rs57747440 chr13:113894750 C/A cg18105134 chr13:113819100 PROZ -0.34 -5.52 -0.44 1.9e-7 Platelet distribution width; TGCT cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg19570321 chr11:63258214 HRASLS5 0.44 5.05 0.41 1.57e-6 Platelet count; TGCT cis rs1372520 0.684 rs1442148 chr4:90748846 T/A cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs854765 0.583 rs66531105 chr17:17809001 C/T cg09796270 chr17:17721594 SREBF1 0.23 4.68 0.39 7.36e-6 Total body bone mineral density; TGCT cis rs801193 1.000 rs3800812 chr7:66223461 T/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 8.09e-7 Aortic root size; TGCT cis rs11190604 0.943 rs3750632 chr10:102279295 G/C cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1048238 0.506 rs848194 chr1:16285342 G/A cg21385522 chr1:16154831 NA -0.57 -6.41 -0.5 2.78e-9 Systolic blood pressure; TGCT cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg07636037 chr3:49044803 WDR6 0.83 8.06 0.59 5.4e-13 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs80033912 0.640 rs6785832 chr3:49224316 C/T cg07636037 chr3:49044803 WDR6 0.63 6.15 0.48 9.82e-9 Intelligence (multi-trait analysis); TGCT cis rs911263 0.603 rs2180769 chr14:68799102 A/T cg18825221 chr14:68749962 RAD51L1 0.23 4.47 0.37 1.73e-5 Primary biliary cholangitis; TGCT cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg18230493 chr5:56204884 C5orf35 0.69 5.93 0.47 2.75e-8 Initial pursuit acceleration; TGCT cis rs875971 0.862 rs12698526 chr7:65969105 T/C cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs3774830 0.534 rs7687596 chr4:5472092 C/T cg26943120 chr4:5472116 STK32B -0.29 -7.44 -0.56 1.49e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs910187 0.678 rs1046664 chr20:45817223 G/A cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs8180040 0.764 rs13062022 chr3:47169375 G/A cg27129171 chr3:47204927 SETD2 0.74 9.88 0.66 2.48e-17 Colorectal cancer; TGCT cis rs9291683 0.620 rs7699512 chr4:10125808 C/T cg11266682 chr4:10021025 SLC2A9 -0.45 -5.32 -0.43 4.65e-7 Bone mineral density; TGCT cis rs931608 1.000 rs931608 chr19:22614122 A/C cg23859931 chr19:22123797 NA 0.6 4.66 0.39 7.99e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs698813 0.604 rs1988663 chr2:44492753 C/T cg00619915 chr2:44497795 NA -0.24 -5.5 -0.44 2.05e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs1023500 0.596 rs5751204 chr22:42433801 C/T cg15557168 chr22:42548783 NA -0.19 -4.91 -0.4 2.78e-6 Schizophrenia; TGCT cis rs1215050 0.765 rs783947 chr4:99012943 T/C cg17366294 chr4:99064904 C4orf37 -0.54 -5.86 -0.47 3.98e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4252435 0.614 rs28440780 chr7:142596824 G/T cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs11785693 0.862 rs62491202 chr8:5001470 C/A cg26367366 chr8:4980734 NA 0.58 4.59 0.38 1.06e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs7568458 0.660 rs6722691 chr2:85758352 C/T cg17127132 chr2:85788382 GGCX 0.51 4.73 0.39 5.89e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4665809 1.000 rs6546767 chr2:26328746 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs611744 0.967 rs594405 chr8:109193607 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs1670533 1.000 rs935971 chr4:1045265 G/A cg20887711 chr4:1340912 KIAA1530 0.74 5.57 0.45 1.51e-7 Recombination rate (females); TGCT cis rs7474896 0.537 rs1208591 chr10:38212502 A/T cg13720705 chr10:37990370 NA 0.35 4.44 0.37 1.97e-5 Obesity (extreme); TGCT cis rs79149102 0.579 rs12591994 chr15:75320306 A/G cg09165964 chr15:75287851 SCAMP5 -1.04 -5.48 -0.44 2.28e-7 Lung cancer; TGCT cis rs9911578 1.000 rs9901114 chr17:56575208 G/A cg12560992 chr17:57184187 TRIM37 -0.75 -9.1 -0.63 1.91e-15 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.501 rs4818019 chr21:40694456 T/A cg17971929 chr21:40555470 PSMG1 -0.51 -4.56 -0.38 1.19e-5 Menarche (age at onset); TGCT cis rs11696845 0.666 rs6073533 chr20:43361082 G/T cg25301532 chr20:43378953 KCNK15 -0.5 -5.35 -0.43 4.02e-7 Obesity-related traits; TGCT cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9814567 0.896 rs11915964 chr3:134348930 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.85 7.79 0.57 2.3e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs7819412 0.806 rs6980856 chr8:10938260 A/G cg06636001 chr8:8085503 FLJ10661 0.77 7.08 0.54 9.66e-11 Triglycerides; TGCT cis rs8014204 0.905 rs8014289 chr14:75377352 A/G cg06637938 chr14:75390232 RPS6KL1 -0.74 -6.97 -0.53 1.68e-10 Caffeine consumption; TGCT cis rs422249 0.547 rs174535 chr11:61551356 T/C cg19610905 chr11:61596333 FADS2 -1.08 -10.94 -0.7 6.47e-20 Trans fatty acid levels; TGCT cis rs9381040 0.610 rs2268191 chr6:41027653 G/C cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT cis rs2439831 0.850 rs28891769 chr15:44072860 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.99 10.88 0.7 8.97e-20 Intelligence (multi-trait analysis); TGCT cis rs483180 0.512 rs612430 chr1:120216025 A/G cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Macular telangiectasia type 2; TGCT cis rs79839061 0.667 rs73207777 chr4:836046 A/G cg07828340 chr4:882639 GAK 0.36 4.75 0.39 5.58e-6 Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs7809755 chr7:116110732 C/T cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs9372498 0.536 rs17080302 chr6:118854037 A/G cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT cis rs6486730 0.508 rs7133440 chr12:129269244 A/C cg09035930 chr12:129282057 SLC15A4 -0.43 -6.5 -0.5 1.76e-9 Systemic lupus erythematosus; TGCT cis rs2933343 0.729 rs1683780 chr3:128640239 C/T cg11901034 chr3:128598214 ACAD9 -0.69 -6.57 -0.51 1.24e-9 IgG glycosylation; TGCT cis rs319204 0.851 rs319189 chr5:146270355 A/T cg25021259 chr5:146258546 PPP2R2B 0.35 4.49 0.37 1.63e-5 Schizophrenia; TGCT cis rs2228479 0.850 rs11641147 chr16:89813589 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7726839 0.574 rs72705017 chr5:623733 G/A cg16624210 chr5:671434 TPPP 0.43 4.68 0.39 7.5e-6 Obesity-related traits; TGCT cis rs35146811 0.624 rs1727134 chr7:99813672 T/C cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs28493229 0.522 rs2233152 chr19:41281016 C/T cg11601297 chr19:41224147 ITPKC;ADCK4 0.58 5.1 0.42 1.25e-6 Kawasaki disease; TGCT cis rs2762353 0.574 rs4419666 chr6:25693274 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.73 7.49 0.56 1.11e-11 Blood metabolite levels; TGCT cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs74233809 1.000 rs75970938 chr10:104793648 T/C cg05855489 chr10:104503620 C10orf26 0.77 4.55 0.38 1.27e-5 Birth weight; TGCT trans rs1005277 0.579 rs2505197 chr10:38393310 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs797680 0.856 rs535760 chr1:93728758 T/A cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg02725872 chr8:58115012 NA -0.38 -4.73 -0.39 5.94e-6 Developmental language disorder (linguistic errors); TGCT cis rs1483890 0.723 rs12629224 chr3:69411188 T/C cg22125112 chr3:69402811 FRMD4B 0.29 4.71 0.39 6.53e-6 Resting heart rate; TGCT cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg23205692 chr1:25664452 TMEM50A 0.52 5.36 0.43 3.96e-7 Erythrocyte sedimentation rate; TGCT cis rs10465746 0.935 rs12410617 chr1:84379461 G/C cg10977910 chr1:84465055 TTLL7 0.63 6.16 0.48 9.32e-9 Obesity-related traits; TGCT cis rs875971 0.522 rs1617484 chr7:65463095 G/A cg00343986 chr7:65444356 GUSB 0.24 5.31 0.43 4.81e-7 Aortic root size; TGCT cis rs10940138 1.000 rs10940138 chr5:67194469 C/T ch.5.1281357F chr5:67228439 NA 0.41 4.73 0.39 6.13e-6 Menarche (age at onset); TGCT cis rs9911578 1.000 rs1494977 chr17:56863064 C/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs11190604 1.000 rs2495751 chr10:102327260 A/G cg16342193 chr10:102329863 NA -0.42 -5.39 -0.44 3.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6952808 0.608 rs58120505 chr7:2029867 T/C cg14004847 chr7:1930337 MAD1L1 -0.27 -4.54 -0.38 1.33e-5 Bipolar disorder and schizophrenia; TGCT cis rs12134133 1.000 rs11582249 chr1:207441608 G/A cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs57994353 0.897 rs11999532 chr9:139371405 G/C cg13741927 chr9:139327495 INPP5E -0.24 -5.42 -0.44 2.93e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs17331151 0.541 rs1139106 chr3:52871101 G/A cg12962167 chr3:53033115 SFMBT1 0.43 4.9 0.4 2.92e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6809651 0.524 rs12638263 chr3:185795855 A/C cg00760338 chr3:185826511 ETV5 -0.63 -4.81 -0.4 4.36e-6 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg16228356 chr17:43848958 NA -0.26 -4.53 -0.38 1.37e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7914558 1.000 rs10883826 chr10:104830819 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.85 -0.4 3.58e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6088580 0.609 rs6059845 chr20:33036500 G/A cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs918629 0.716 rs3756703 chr5:95276063 G/A cg16656078 chr5:95278638 ELL2 -0.27 -4.67 -0.39 7.55e-6 IgG glycosylation; TGCT cis rs3087591 1.000 rs2905877 chr17:29543269 A/C cg24425628 chr17:29625626 OMG;NF1 -0.5 -7.33 -0.55 2.63e-11 Hip circumference; TGCT trans rs7615952 0.800 rs13086460 chr3:125646417 C/T cg07211511 chr3:129823064 LOC729375 -0.48 -8.02 -0.58 6.91e-13 Blood pressure (smoking interaction); TGCT trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg07870213 chr5:140052090 DND1 0.65 7.75 0.57 2.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg13665807 chr20:60559372 TAF4 -0.53 -5.41 -0.44 3.06e-7 Body mass index; TGCT cis rs1499614 1.000 rs34250985 chr7:66161062 A/T cg18252515 chr7:66147081 NA -1.15 -6.48 -0.5 2e-9 Gout; TGCT cis rs881375 1.000 rs1609810 chr9:123642351 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.47 0.44 2.33e-7 Rheumatoid arthritis; TGCT cis rs2996428 0.709 rs6424052 chr1:3713746 A/G cg17848003 chr1:3704513 LRRC47 0.17 4.56 0.38 1.22e-5 Red cell distribution width; TGCT cis rs3749237 0.595 rs7643845 chr3:49530711 A/G cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs1669338 0.588 rs73009149 chr3:3220473 G/C cg16797762 chr3:3221439 CRBN -0.87 -5.5 -0.44 2.12e-7 White matter integrity; TGCT cis rs3008870 1.000 rs3008855 chr1:67386204 A/G cg08660285 chr1:67390436 MIER1;WDR78 -1.01 -10.62 -0.69 3.91e-19 Lymphocyte percentage of white cells; TGCT cis rs6088580 0.634 rs1205345 chr20:32914699 A/G cg06115741 chr20:33292138 TP53INP2 -0.53 -4.66 -0.39 7.94e-6 Glomerular filtration rate (creatinine); TGCT cis rs2463822 0.583 rs17709552 chr11:62040519 A/G cg06239285 chr11:62104954 ASRGL1 -0.89 -5.95 -0.47 2.57e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs10875595 0.779 rs2338532 chr5:140675264 G/A cg24830062 chr5:140700576 TAF7 -0.61 -5.14 -0.42 1.04e-6 Pulmonary function decline; TGCT cis rs1371867 0.846 rs1660345 chr8:101322762 C/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs2806561 0.765 rs652783 chr1:23514313 G/T cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs548181 0.621 rs2912098 chr11:125528569 C/T cg03464685 chr11:125439445 EI24 1.27 9.56 0.65 1.46e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs11030122 0.702 rs1452047 chr11:3991648 A/C cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs2204008 0.744 rs67889662 chr12:38327042 T/A cg13010199 chr12:38710504 ALG10B 0.61 4.77 0.39 5.11e-6 Bladder cancer; TGCT cis rs10883723 0.810 rs7069356 chr10:104254359 G/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7923609 0.811 rs4746204 chr10:65328518 C/T cg08743896 chr10:65200160 JMJD1C 0.32 4.46 0.37 1.82e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg24846343 chr22:24311635 DDTL 0.23 5.7 0.46 8.19e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs12477438 0.501 rs7349217 chr2:99815146 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.88 8.83 0.62 8.31e-15 Chronic sinus infection; TGCT cis rs314370 0.570 rs314313 chr7:100423365 C/T cg10426581 chr7:100472382 SRRT -0.7 -7.26 -0.55 3.8e-11 Resting heart rate; TGCT cis rs10131894 0.575 rs2159904 chr14:75432179 G/T cg08847533 chr14:75593920 NEK9 0.68 6.21 0.49 7.44e-9 Coronary artery disease; TGCT cis rs7216064 1.000 rs8074078 chr17:65838743 A/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg18305652 chr10:134549665 INPP5A 0.35 5.94 0.47 2.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6754311 0.906 rs4954387 chr2:136784344 A/G cg07169764 chr2:136633963 MCM6 0.54 5.07 0.41 1.4e-6 Mosquito bite size; TGCT cis rs941408 0.963 rs2537854 chr19:2786726 A/C cg06609049 chr19:2785107 THOP1 0.79 7.83 0.58 1.84e-12 Total cholesterol levels; TGCT cis rs614226 1.000 rs614226 chr12:120974510 C/T cg10072921 chr12:121022843 NA 0.44 4.74 0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs7020830 0.825 rs10973248 chr9:37197768 C/T cg14294708 chr9:37120828 ZCCHC7 1.19 15.69 0.82 3.1e-31 Schizophrenia; TGCT cis rs4332037 0.539 rs57148375 chr7:2025001 G/C cg25834613 chr7:1915315 MAD1L1 -0.47 -4.51 -0.38 1.48e-5 Bipolar disorder; TGCT cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs6657613 0.869 rs9435662 chr1:17314942 G/A cg21692666 chr1:17199302 NA -0.42 -4.52 -0.38 1.43e-5 Hip circumference adjusted for BMI; TGCT cis rs10751667 0.643 rs7396767 chr11:938808 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs908922 0.651 rs11205035 chr1:152532832 A/G cg20991723 chr1:152506922 NA 0.44 5.91 0.47 3.08e-8 Hair morphology; TGCT cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs651907 0.557 rs7651721 chr3:101393583 C/A cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs9926296 0.609 rs4785714 chr16:89798404 G/T cg03388025 chr16:89894329 SPIRE2 -0.32 -4.8 -0.4 4.41e-6 Vitiligo; TGCT cis rs2290402 0.536 rs45486093 chr4:875671 T/C cg23332689 chr4:987652 IDUA;SLC26A1 0.34 5.07 0.41 1.44e-6 Type 2 diabetes; TGCT cis rs936229 0.784 rs12906946 chr15:75153140 A/G cg10253484 chr15:75165896 SCAMP2 -0.78 -6.49 -0.5 1.9e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg12311346 chr5:56204834 C5orf35 -0.82 -7.96 -0.58 9.17e-13 Initial pursuit acceleration; TGCT cis rs11673344 0.523 rs36096221 chr19:37551740 G/A cg08039142 chr19:36980659 ZNF566 0.51 4.69 0.39 6.97e-6 Obesity-related traits; TGCT cis rs698833 0.518 rs7560807 chr2:44557089 C/T cg23552047 chr2:44669647 C2orf34 0.28 4.49 0.37 1.63e-5 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs9457247 1.000 rs365189 chr6:167384545 G/A cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs12477438 0.520 rs13018891 chr2:99755099 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs2180341 0.513 rs12196828 chr6:127696864 C/T cg24812749 chr6:127587940 RNF146 0.62 5.38 0.44 3.5e-7 Breast cancer; TGCT cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg20999797 chr1:1681921 NA 0.18 4.78 0.39 4.93e-6 Body mass index; TGCT cis rs3771570 1.000 rs17386555 chr2:242371825 G/A cg21155796 chr2:242212141 HDLBP 0.93 6.62 0.51 9.86e-10 Prostate cancer; TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs6912958 0.559 rs173333 chr6:88047754 T/G cg04972856 chr6:88032051 C6orf162;GJB7 0.4 4.71 0.39 6.65e-6 Monocyte percentage of white cells; TGCT cis rs4820539 1.000 rs4820539 chr22:23477970 C/T cg14186256 chr22:23484241 RTDR1 -1.01 -13.19 -0.76 2.34e-25 Bone mineral density; TGCT cis rs79149102 0.579 rs76518150 chr15:75292721 C/G cg09165964 chr15:75287851 SCAMP5 -1.07 -5.81 -0.46 4.89e-8 Lung cancer; TGCT cis rs7086627 0.515 rs11202960 chr10:82209807 G/A cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs4888262 0.526 rs7205258 chr16:74642539 C/T cg01733217 chr16:74700730 RFWD3 0.74 7.47 0.56 1.23e-11 Testicular germ cell tumor; TGCT cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg23205692 chr1:25664452 TMEM50A 0.53 5.48 0.44 2.32e-7 Erythrocyte sedimentation rate; TGCT cis rs6663390 0.510 rs1932818 chr1:208078257 C/T cg03990033 chr1:208084030 CD34 0.64 6.05 0.48 1.57e-8 Facial morphology (factor 18); TGCT cis rs4660261 0.526 rs2906466 chr1:44322220 A/G cg12908607 chr1:44402522 ARTN -0.64 -7.74 -0.57 3e-12 Intelligence (multi-trait analysis); TGCT cis rs1475911 1.000 rs12482477 chr21:43517233 T/A cg24372256 chr21:43528868 UMODL1;C21orf128 -0.25 -4.79 -0.4 4.59e-6 IgG glycosylation; TGCT cis rs35306767 0.903 rs13377166 chr10:886259 G/A cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs9467773 1.000 rs6924838 chr6:26571756 C/T cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs4663866 1.000 rs4663866 chr2:239150815 A/C cg17283117 chr2:239148619 HES6 0.98 4.5 0.37 1.55e-5 Irritable bowel syndrome; TGCT cis rs6597981 0.604 rs7945912 chr11:750849 A/T cg20225915 chr11:805726 LRDD -0.33 -4.7 -0.39 6.66e-6 Breast cancer; TGCT cis rs10791097 0.694 rs1893018 chr11:130756632 T/C cg05962950 chr11:130786565 SNX19 0.9 11.06 0.7 3.32e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs782590 0.967 rs4672054 chr2:55773093 C/A cg18811423 chr2:55921094 PNPT1 0.66 7.14 0.54 7.11e-11 Metabolic syndrome; TGCT cis rs3858526 1.000 rs3858527 chr11:5959848 G/A cg13902645 chr11:5959945 NA -0.43 -4.65 -0.39 8.43e-6 DNA methylation (variation); TGCT cis rs782590 0.607 rs2061032 chr2:55679490 T/C cg03859395 chr2:55845619 SMEK2 0.61 5.3 0.43 5.12e-7 Metabolic syndrome; TGCT cis rs3849570 0.533 rs6785385 chr3:81989850 A/G cg07356753 chr3:81810745 GBE1 -0.54 -4.51 -0.38 1.49e-5 Waist circumference;Body mass index; TGCT cis rs651907 0.557 rs7612283 chr3:101434919 C/T cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.02 -0.53 1.27e-10 Colorectal cancer; TGCT cis rs7940866 0.845 rs1433976 chr11:130875123 C/T cg12179176 chr11:130786555 SNX19 -0.49 -4.9 -0.4 2.99e-6 Schizophrenia; TGCT cis rs9902453 1.000 rs6505152 chr17:28331466 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs2224391 0.590 rs72815603 chr6:5278701 A/C cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -5.28 -0.43 5.56e-7 Height; TGCT cis rs3020736 0.500 rs5996109 chr22:42493098 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs13064447 0.753 rs9868500 chr3:12747690 A/G cg20675869 chr3:12750130 NA 0.18 4.46 0.37 1.81e-5 Major depression and alcohol dependence; TGCT cis rs9611519 0.964 rs20551 chr22:41548008 A/G cg13695892 chr22:41940480 POLR3H -0.52 -4.76 -0.39 5.23e-6 Neuroticism; TGCT cis rs7945705 0.967 rs10769973 chr11:8928615 C/G cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.1 0.42 1.24e-6 Hemoglobin concentration; TGCT cis rs6920965 0.507 rs12203025 chr6:126192034 C/T cg05901451 chr6:126070800 HEY2 -0.66 -6.5 -0.5 1.81e-9 High light scatter reticulocyte count; TGCT cis rs3125734 0.633 rs4561099 chr10:64041163 T/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.48 -0.37 1.69e-5 Rheumatoid arthritis; TGCT trans rs2624839 0.602 rs2526398 chr3:50187596 G/C cg21665057 chr3:196295764 WDR53;FBXO45 0.78 7.04 0.53 1.17e-10 Intelligence (multi-trait analysis); TGCT cis rs1406084 0.636 rs7591066 chr2:154718471 G/A cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9611519 1.000 rs6002271 chr22:41566595 C/T cg13695892 chr22:41940480 POLR3H -0.5 -4.48 -0.37 1.65e-5 Neuroticism; TGCT cis rs6893300 0.524 rs62404348 chr5:179146026 G/A cg14593053 chr5:179126677 CANX 0.48 5.4 0.44 3.23e-7 Resting heart rate; TGCT cis rs9911578 1.000 rs1631237 chr17:56734695 A/G cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg11062466 chr8:58055876 NA 0.43 4.52 0.38 1.45e-5 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.908 rs17031092 chr2:43809248 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.63 4.52 0.38 1.43e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1532993 0.518 rs28634627 chr4:98561934 C/T cg05340658 chr4:99064831 C4orf37 -0.38 -4.53 -0.38 1.36e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs2204008 0.743 rs11182052 chr12:38450421 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.78 0.57 2.41e-12 Bladder cancer; TGCT cis rs713587 0.521 rs35177510 chr2:25089594 C/A cg01884057 chr2:25150051 NA 0.3 5.65 0.45 1.03e-7 Body mass index in non-asthmatics; TGCT cis rs514406 0.505 rs448788 chr1:53161620 A/G cg24675658 chr1:53192096 ZYG11B 0.75 8.3 0.6 1.51e-13 Monocyte count; TGCT cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg10047753 chr17:41438598 NA -0.62 -6.22 -0.49 6.96e-9 Menopause (age at onset); TGCT cis rs7100689 0.646 rs4601708 chr10:82119583 G/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs9357506 0.967 rs9381441 chr6:46310411 C/T cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs12477438 0.501 rs11688004 chr2:99735052 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs7552404 0.924 rs2153126 chr1:76199345 C/G cg03433033 chr1:76189801 ACADM 0.82 9.91 0.66 2.05e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs769267 0.965 rs2074550 chr19:19387743 A/C cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs524281 0.954 rs549187 chr11:65898631 C/T cg00563793 chr11:65837595 PACS1 0.5 4.52 0.38 1.45e-5 Electroencephalogram traits; TGCT cis rs7909074 0.831 rs11239271 chr10:45376294 A/G cg05187965 chr10:45406764 TMEM72 -0.29 -6.04 -0.48 1.67e-8 Mean corpuscular volume; TGCT cis rs35146811 1.000 rs35146811 chr7:99720994 A/C cg22906224 chr7:99728672 NA 0.55 5.05 0.41 1.52e-6 Coronary artery disease; TGCT cis rs782590 0.902 rs782595 chr2:55845596 C/G cg03859395 chr2:55845619 SMEK2 0.96 12.0 0.73 1.71e-22 Metabolic syndrome; TGCT cis rs7267979 1.000 rs6115140 chr20:25285507 C/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9926296 0.529 rs7195906 chr16:89806347 A/T cg26513180 chr16:89883248 FANCA 1.06 14.79 0.8 3.77e-29 Vitiligo; TGCT cis rs3936340 1.000 rs2278237 chr19:48527902 G/C cg03707168 chr19:49379127 PPP1R15A 0.6 4.56 0.38 1.22e-5 Intelligence; TGCT cis rs1865760 0.566 rs1539183 chr6:26075051 G/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs77741769 0.571 rs989987 chr12:121274062 C/T cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.58e-5 Mean corpuscular volume; TGCT cis rs9611565 0.559 rs132771 chr22:42025350 A/G cg06634786 chr22:41940651 POLR3H 0.88 8.38 0.6 9.48e-14 Vitiligo; TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.72 -0.39 6.33e-6 Prudent dietary pattern; TGCT cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6424115 0.830 rs2229585 chr1:24200921 T/C cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs7100689 0.646 rs1340382 chr10:82096997 G/C cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs826838 0.935 rs11169547 chr12:39185625 C/A cg13010199 chr12:38710504 ALG10B 0.77 6.09 0.48 1.31e-8 Heart rate; TGCT cis rs10940138 0.830 rs6867554 chr5:67207725 A/G ch.5.1281357F chr5:67228439 NA 0.44 4.91 0.4 2.83e-6 Menarche (age at onset); TGCT cis rs877282 1.000 rs112522746 chr10:772288 T/C cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs72843506 0.586 rs59890010 chr17:19863673 C/T cg18979559 chr17:20280153 CCDC144C -0.59 -4.5 -0.37 1.53e-5 Schizophrenia; TGCT cis rs9972944 0.902 rs9972881 chr17:63771334 A/G cg07283582 chr17:63770753 CCDC46 0.28 5.89 0.47 3.34e-8 Total body bone mineral density; TGCT cis rs12458462 0.859 rs35493271 chr18:77448793 G/T cg11879182 chr18:77439856 CTDP1 0.7 7.83 0.58 1.88e-12 Monocyte count; TGCT cis rs2230307 0.536 rs834277 chr1:100510855 T/G cg24955406 chr1:100503596 HIAT1 0.74 4.86 0.4 3.41e-6 Carotid intima media thickness; TGCT cis rs56104184 0.723 rs1058483 chr19:49407660 G/A cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs951366 0.873 rs823118 chr1:205723572 C/T cg07157834 chr1:205819609 PM20D1 0.34 5.0 0.41 1.89e-6 Menarche (age at onset); TGCT cis rs6570726 0.791 rs401331 chr6:145831408 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7208859 0.673 rs60020217 chr17:29185054 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs929354 0.772 rs6967764 chr7:156994964 C/T cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs2708977 0.614 rs12477963 chr2:97261593 G/A cg01950434 chr2:97203154 ARID5A 0.54 4.49 0.37 1.62e-5 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7769051 1.000 rs9493446 chr6:133125643 C/T cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs7666738 0.830 rs1426672 chr4:98923984 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7432375 0.901 rs35874192 chr3:136470004 G/C cg12473912 chr3:136751656 NA -0.36 -5.03 -0.41 1.68e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs11971779 0.793 rs4728464 chr7:139017670 C/T cg07862535 chr7:139043722 LUC7L2 -0.74 -5.89 -0.47 3.32e-8 Diisocyanate-induced asthma; TGCT cis rs12200560 0.505 rs60879781 chr6:97075466 A/T cg06623918 chr6:96969491 KIAA0776 0.59 5.06 0.41 1.44e-6 Coronary heart disease; TGCT cis rs9467711 0.606 rs9358935 chr6:26369587 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.87 0.4 3.38e-6 Prudent dietary pattern; TGCT cis rs7824557 0.679 rs6601579 chr8:11138098 T/A cg21775007 chr8:11205619 TDH -0.6 -5.65 -0.45 1.03e-7 Retinal vascular caliber; TGCT cis rs950169 0.922 rs11630760 chr15:85113337 G/T cg17173187 chr15:85201210 NMB 0.47 4.93 0.4 2.62e-6 Schizophrenia; TGCT cis rs4750440 0.576 rs2447011 chr10:14032199 C/T cg25464840 chr10:14372910 FRMD4A 0.33 4.46 0.37 1.82e-5 Adiponectin levels; TGCT cis rs154659 0.961 rs164739 chr16:89667699 C/G cg01710450 chr16:89662404 CPNE7 -0.4 -7.12 -0.54 7.83e-11 Tanning; TGCT cis rs7246657 0.722 rs2972437 chr19:38210511 G/T cg18154014 chr19:37997991 ZNF793 0.72 5.06 0.41 1.48e-6 Coronary artery calcification; TGCT cis rs28595532 0.920 rs114390336 chr4:119771452 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs9443189 0.762 rs1321162 chr6:76456347 C/T cg01950844 chr6:76311363 SENP6 0.6 4.48 0.37 1.69e-5 Prostate cancer; TGCT cis rs174601 0.861 rs174581 chr11:61606683 G/A cg19610905 chr11:61596333 FADS2 -0.96 -9.43 -0.65 3.08e-16 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs76878669 0.561 rs3177514 chr11:66130358 T/G cg18002602 chr11:66138449 SLC29A2 0.53 6.58 0.51 1.18e-9 Educational attainment (years of education); TGCT cis rs8072100 0.967 rs4580230 chr17:45738861 G/A cg08085267 chr17:45401833 C17orf57 -0.47 -5.13 -0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4888262 0.508 rs4544266 chr16:74660993 C/A cg01733217 chr16:74700730 RFWD3 0.7 7.02 0.53 1.26e-10 Testicular germ cell tumor; TGCT cis rs514406 0.679 rs541852 chr1:53256834 A/G cg25767906 chr1:53392781 SCP2 0.6 7.15 0.54 6.42e-11 Monocyte count; TGCT cis rs28493229 0.582 rs78915350 chr19:41160609 A/G cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.16 0.42 9.45e-7 Kawasaki disease; TGCT cis rs1127311 0.905 rs6702449 chr1:154583210 A/C cg17218026 chr1:154582156 ADAR 0.31 7.7 0.57 3.72e-12 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs79349575 0.783 rs4255820 chr17:46996583 T/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs4812048 0.696 rs6070694 chr20:57591126 G/A cg14073986 chr20:57617431 SLMO2 0.63 4.67 0.39 7.71e-6 Mean platelet volume; TGCT cis rs10207060 0.500 rs7585903 chr2:240682481 A/C cg07506560 chr2:240697449 NA 0.48 5.27 0.43 5.96e-7 Obesity-related traits; TGCT cis rs4285028 0.948 rs73855480 chr3:121676646 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs17125944 0.505 rs77433996 chr14:53212263 G/A cg00686598 chr14:53173677 PSMC6 1.08 6.35 0.5 3.79e-9 Alzheimer's disease (late onset); TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg24675658 chr1:53192096 ZYG11B -0.71 -8.23 -0.59 2.14e-13 Monocyte count; TGCT cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg20887711 chr4:1340912 KIAA1530 0.85 7.32 0.55 2.75e-11 Longevity; TGCT cis rs2456568 0.571 rs12807496 chr11:93693064 A/G cg26875233 chr11:93583750 C11orf90 0.43 5.16 0.42 9.71e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10504229 0.817 rs10504230 chr8:58197150 A/G cg24829409 chr8:58192753 C8orf71 0.6 5.39 0.44 3.4e-7 Developmental language disorder (linguistic errors); TGCT cis rs265548 0.608 rs36690 chr19:17910483 C/T cg21960279 chr19:17905606 B3GNT3 0.5 5.81 0.46 4.94e-8 Tumor biomarkers; TGCT cis rs617219 0.710 rs2591386 chr5:78561373 C/T cg09550809 chr5:78407562 BHMT 0.38 5.26 0.43 6.2e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4919044 0.808 rs1750741 chr10:94804530 G/T cg05127821 chr10:94822908 CYP26C1 -0.75 -4.85 -0.4 3.67e-6 Coronary artery disease; TGCT cis rs7103648 0.932 rs7104036 chr11:47462140 A/G cg20307385 chr11:47447363 PSMC3 1.07 13.03 0.76 5.56e-25 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs2836974 0.931 rs2776309 chr21:40715791 A/G cg06238570 chr21:40685208 BRWD1 0.67 5.84 0.46 4.4e-8 Cognitive function; TGCT cis rs4851266 0.865 rs11123818 chr2:100867308 G/A cg07810366 chr2:100720526 AFF3 -0.36 -5.21 -0.42 7.59e-7 Educational attainment; TGCT cis rs7666738 0.752 rs35436270 chr4:99088280 G/A cg17366294 chr4:99064904 C4orf37 0.71 5.48 0.44 2.27e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4820539 1.000 rs2267002 chr22:23456702 T/C cg21100191 chr22:23484243 RTDR1 0.95 11.39 0.72 5.18e-21 Bone mineral density; TGCT cis rs6121246 0.512 rs6058384 chr20:30276409 A/T cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs975752 0.867 rs2270962 chr10:102016044 C/T cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs709400 0.663 rs1803283 chr14:103986255 C/T cg26031613 chr14:104095156 KLC1 -0.85 -8.91 -0.62 5.43e-15 Body mass index; TGCT cis rs892961 0.932 rs747481 chr17:75412143 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs736801 0.891 rs10900809 chr5:131826322 G/A cg02551604 chr5:131831745 NA 0.57 4.71 0.39 6.64e-6 Breast cancer;Mosquito bite size; TGCT cis rs611744 0.625 rs11991891 chr8:109294858 G/A cg21045802 chr8:109455806 TTC35 0.74 7.77 0.57 2.59e-12 Dupuytren's disease; TGCT cis rs12142240 0.698 rs72677599 chr1:46834251 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.8 -0.4 4.46e-6 Menopause (age at onset); TGCT cis rs7772486 0.875 rs9403765 chr6:146368041 C/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.71 -0.39 6.52e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4664308 0.810 rs59019419 chr2:161061287 G/A cg03641300 chr2:160917029 PLA2R1 -0.27 -6.72 -0.52 6e-10 Idiopathic membranous nephropathy; TGCT cis rs1997103 1.000 rs4947504 chr7:55409428 T/C cg17469321 chr7:55412551 NA 0.64 6.58 0.51 1.18e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs8072100 0.738 rs3736438 chr17:45486651 T/G cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1062177 1.000 rs12515762 chr5:151209922 G/T cg12924095 chr5:151150029 G3BP1 0.36 5.18 0.42 8.79e-7 Preschool internalizing problems; TGCT cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs317689 0.876 rs547332 chr12:69743639 C/G cg19645103 chr12:69753606 YEATS4 -0.56 -4.57 -0.38 1.14e-5 Response to diuretic therapy; TGCT cis rs1797081 0.504 rs2995476 chr10:16871358 C/A cg23933602 chr10:16859644 RSU1 0.79 8.05 0.59 5.83e-13 Platelet distribution width; TGCT cis rs28595532 0.920 rs17324807 chr4:119770638 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg04546413 chr19:29218101 NA 0.73 6.61 0.51 1.02e-9 Methadone dose in opioid dependence; TGCT cis rs9303401 0.659 rs17222691 chr17:56771096 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg08392591 chr16:89556376 ANKRD11 0.55 5.09 0.42 1.32e-6 Multiple myeloma (IgH translocation); TGCT cis rs709400 0.663 rs7152202 chr14:103886757 A/G cg26031613 chr14:104095156 KLC1 0.84 9.63 0.65 1.02e-16 Body mass index; TGCT cis rs6570726 0.720 rs412623 chr6:145883257 C/A cg23711669 chr6:146136114 FBXO30 0.83 8.66 0.61 2.09e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.789 rs6083820 chr20:25354178 G/A cg16686733 chr20:25566563 NINL -0.49 -4.62 -0.38 9.44e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11122272 0.735 rs2749705 chr1:231526696 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.3 -0.49 4.72e-9 Hemoglobin concentration; TGCT cis rs4478037 1.000 rs4074418 chr3:33161165 G/T cg19404215 chr3:33155277 CRTAP 1.28 8.55 0.61 3.75e-14 Major depressive disorder; TGCT cis rs9388451 0.874 rs1159974 chr6:126090277 C/T cg05901451 chr6:126070800 HEY2 1.02 14.91 0.8 1.92e-29 Brugada syndrome; TGCT cis rs2760061 0.626 rs2313118 chr1:228118084 T/C cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs28595532 0.920 rs116821181 chr4:119734892 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs763121 0.925 rs5750654 chr22:39051428 T/C cg06022373 chr22:39101656 GTPBP1 0.78 7.97 0.58 8.82e-13 Menopause (age at onset); TGCT cis rs13191362 0.938 rs13208970 chr6:163006368 G/T cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9814567 0.712 rs4245905 chr3:134328864 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9389248 0.690 rs1028314 chr6:135255710 A/C cg22676075 chr6:135203613 NA -0.5 -5.04 -0.41 1.59e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs35883536 0.528 rs1414414 chr1:101028907 T/C cg06223162 chr1:101003688 GPR88 0.42 8.22 0.59 2.25e-13 Monocyte count; TGCT trans rs8073060 0.516 rs2376177 chr17:33938089 T/G cg19694781 chr19:47549865 TMEM160 -0.61 -13.7 -0.78 1.39e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1552244 0.706 rs279545 chr3:9972493 A/G cg00149659 chr3:10157352 C3orf10 0.59 4.73 0.39 6.04e-6 Alzheimer's disease; TGCT cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.9 0.53 2.39e-10 Electroencephalogram traits; TGCT cis rs12950390 0.853 rs17700008 chr17:45863591 A/C cg06532163 chr17:45867833 NA -0.37 -5.96 -0.47 2.45e-8 IgG glycosylation; TGCT cis rs9653442 0.900 rs1160544 chr2:100832218 A/C cg22139774 chr2:100720529 AFF3 -0.38 -6.15 -0.48 9.83e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs782590 0.934 rs17369191 chr2:55757885 T/C cg03859395 chr2:55845619 SMEK2 0.91 11.32 0.71 7.6e-21 Metabolic syndrome; TGCT cis rs7809950 1.000 rs2808 chr7:107260856 A/G cg23024343 chr7:107201750 COG5 0.36 5.63 0.45 1.15e-7 Coronary artery disease; TGCT cis rs3947 0.951 rs1692817 chr8:11704719 C/A cg02840367 chr8:11660030 FDFT1 0.89 6.47 0.5 2e-9 Blood protein levels; TGCT cis rs9902453 0.619 rs2617866 chr17:28076217 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -7.91 -0.58 1.19e-12 Coffee consumption (cups per day); TGCT trans rs2727020 0.664 rs4929893 chr11:49196332 C/T cg15704280 chr7:45808275 SEPT13 -0.7 -7.67 -0.57 4.26e-12 Coronary artery disease; TGCT cis rs7940866 0.834 rs10791108 chr11:130849354 T/A cg05962950 chr11:130786565 SNX19 0.71 6.96 0.53 1.79e-10 Schizophrenia; TGCT cis rs763014 0.931 rs7192508 chr16:630367 C/T cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs9486715 0.830 rs1475748 chr6:97034143 T/C cg06623918 chr6:96969491 KIAA0776 -1.11 -15.34 -0.81 1.96e-30 Headache; TGCT cis rs637571 0.510 rs10750772 chr11:65577427 C/T cg04055107 chr11:65626734 MUS81;CFL1 -0.67 -6.01 -0.48 1.9e-8 Eosinophil percentage of white cells; TGCT cis rs6922269 0.859 rs4869954 chr6:151250567 A/G cg01013955 chr6:150918915 NA -0.29 -5.04 -0.41 1.59e-6 Coronary heart disease; TGCT cis rs9650657 0.801 rs4841437 chr8:10596795 T/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.55 -0.38 1.25e-5 Neuroticism; TGCT cis rs4713118 0.527 rs4713151 chr6:28136356 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Parkinson's disease; TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg17178900 chr1:205818956 PM20D1 0.56 6.87 0.53 2.72e-10 Menarche (age at onset); TGCT cis rs559928 0.593 rs112275221 chr11:63936994 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.56 0.38 1.22e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs11190604 1.000 rs2489046 chr10:102346282 A/C cg16342193 chr10:102329863 NA -0.39 -4.92 -0.4 2.72e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9300255 0.679 rs12829456 chr12:123725395 C/T cg00376283 chr12:123451042 ABCB9 -0.74 -5.03 -0.41 1.66e-6 Neutrophil percentage of white cells; TGCT cis rs72945132 0.619 rs34552378 chr11:70243208 C/T cg00319359 chr11:70116639 PPFIA1 1.01 7.03 0.53 1.21e-10 Coronary artery disease; TGCT cis rs7100689 0.577 rs10749560 chr10:82092801 G/T cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg03806693 chr22:41940476 POLR3H -1.04 -10.57 -0.69 5.2e-19 Vitiligo; TGCT cis rs9653442 0.522 rs4851274 chr2:100870862 T/C cg22139774 chr2:100720529 AFF3 -0.37 -5.81 -0.46 5.05e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10782582 0.546 rs79652169 chr1:76233882 G/A cg10523679 chr1:76189770 ACADM -0.61 -6.13 -0.48 1.09e-8 Daytime sleep phenotypes; TGCT trans rs4650994 0.816 rs2209169 chr1:178601492 C/T cg05059571 chr16:84539110 KIAA1609 0.42 7.57 0.56 7.21e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2404602 0.669 rs12595313 chr15:76978370 A/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs5750830 0.594 rs9611165 chr22:39775250 A/G cg05872129 chr22:39784769 NA -0.84 -8.83 -0.62 8.39e-15 Intelligence (multi-trait analysis); TGCT cis rs5769765 0.542 rs738707 chr22:50250827 G/A cg22709217 chr22:50311962 ALG12;CRELD2 0.97 6.35 0.5 3.69e-9 Schizophrenia; TGCT cis rs4665809 0.941 rs2289021 chr2:26362515 A/C cg22920501 chr2:26401640 FAM59B 0.65 5.36 0.43 3.85e-7 Gut microbiome composition (summer); TGCT cis rs7429990 0.932 rs11130155 chr3:48140428 A/C cg11946769 chr3:48343235 NME6 -0.57 -4.76 -0.39 5.39e-6 Educational attainment (years of education); TGCT cis rs561341 0.700 rs8079471 chr17:30218317 A/G cg13647721 chr17:30228624 UTP6 0.59 5.21 0.42 7.66e-7 Hip circumference adjusted for BMI; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg24675658 chr1:53192096 ZYG11B -0.71 -7.87 -0.58 1.5e-12 Monocyte count; TGCT cis rs2836974 0.644 rs719230 chr21:40676307 C/T cg06238570 chr21:40685208 BRWD1 -0.8 -9.17 -0.64 1.3e-15 Cognitive function; TGCT cis rs9467773 1.000 rs3736781 chr6:26505362 G/A cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs524281 0.814 rs1055615 chr11:65846922 C/G cg00563793 chr11:65837595 PACS1 0.57 4.84 0.4 3.73e-6 Electroencephalogram traits; TGCT trans rs7618501 1.000 rs9859153 chr3:49807085 G/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT trans rs4332037 0.707 rs62435132 chr7:1891315 C/T cg25206134 chr2:45395956 NA 0.96 8.1 0.59 4.34e-13 Bipolar disorder; TGCT cis rs2806561 0.765 rs9426692 chr1:23508426 C/T cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs7666738 0.830 rs7657490 chr4:99043973 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs7613875 0.600 rs2624826 chr3:50155468 T/G cg21659725 chr3:3221576 CRBN -0.65 -7.16 -0.54 6.39e-11 Body mass index; TGCT cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg03517284 chr6:25882590 NA -0.72 -6.6 -0.51 1.09e-9 Intelligence (multi-trait analysis); TGCT cis rs7192750 0.538 rs11075911 chr16:71988505 T/C cg06353428 chr16:71660113 MARVELD3 0.74 6.6 0.51 1.09e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9581857 0.556 rs9581864 chr13:28041567 T/C cg22138327 chr13:27999177 GTF3A 0.73 5.7 0.46 8.09e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs763014 0.966 rs15564 chr16:677854 G/T cg27436995 chr16:743998 FBXL16 -0.46 -5.02 -0.41 1.75e-6 Height; TGCT cis rs17125944 0.686 rs4450307 chr14:53334783 G/A cg00686598 chr14:53173677 PSMC6 -0.86 -4.47 -0.37 1.75e-5 Alzheimer's disease (late onset); TGCT cis rs10791097 0.694 rs1050071 chr11:130747231 C/G cg05962950 chr11:130786565 SNX19 0.96 11.49 0.72 3.05e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2224391 0.910 rs7752203 chr6:5260812 C/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -6.05 -0.48 1.61e-8 Height; TGCT cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs739496 0.579 rs12302040 chr12:112288179 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs17712049 0.908 rs62447156 chr7:48201198 A/G cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs9948 0.529 rs2139406 chr2:97366779 A/G cg01990225 chr2:97406019 LMAN2L -0.93 -5.29 -0.43 5.38e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs763121 0.853 rs9607566 chr22:39075434 C/G cg06022373 chr22:39101656 GTPBP1 0.75 7.52 0.56 9.53e-12 Menopause (age at onset); TGCT cis rs6671200 0.920 rs259350 chr1:95724831 G/C cg03123541 chr1:95699097 RWDD3 -0.91 -6.4 -0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs1887596 0.590 rs9581702 chr13:27131688 C/T cg01312412 chr13:27282625 NA 0.27 4.76 0.39 5.33e-6 Facial morphology (factor 3, length of philtrum); TGCT trans rs3780486 1.000 rs3780486 chr9:33139453 C/T cg20290983 chr6:43655470 MRPS18A 1.1 10.62 0.69 3.92e-19 IgG glycosylation; TGCT cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg13397359 chr6:42928475 GNMT 0.72 6.48 0.5 1.93e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg26338869 chr17:61819248 STRADA -0.55 -5.03 -0.41 1.65e-6 Prudent dietary pattern; TGCT cis rs7917772 0.503 rs10748825 chr10:104293609 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3096299 0.934 rs9927904 chr16:89462847 G/A cg06640241 chr16:89574553 SPG7 0.61 5.76 0.46 6.36e-8 Multiple myeloma (IgH translocation); TGCT cis rs3733585 0.605 rs4697710 chr4:10122649 T/C cg11266682 chr4:10021025 SLC2A9 -0.56 -6.45 -0.5 2.28e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7737716 0.500 rs17440213 chr5:118239756 A/G cg21035905 chr5:118964330 FAM170A 0.39 4.56 0.38 1.23e-5 Cerebrospinal P-tau181p levels;Cerebrospinal T-tau levels; TGCT cis rs4711350 1.000 rs943472 chr6:33738442 T/C cg00334056 chr6:33755658 LEMD2 -0.29 -4.63 -0.38 9.08e-6 Schizophrenia; TGCT cis rs72720396 0.789 rs10922910 chr1:91199862 G/T cg13456504 chr1:91191583 NA 0.63 5.43 0.44 2.84e-7 Morning vs. evening chronotype;Chronotype; TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs763014 0.932 rs2269559 chr16:682297 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.45 -0.6 6.8e-14 Height; TGCT cis rs425277 1.000 rs74877653 chr1:2065949 C/T cg24578937 chr1:2090814 PRKCZ 0.33 7.85 0.58 1.71e-12 Height; TGCT cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg06634786 chr22:41940651 POLR3H -0.86 -8.34 -0.6 1.18e-13 Vitiligo; TGCT cis rs6558174 0.965 rs2003908 chr8:22491518 T/C cg03733263 chr8:22462867 KIAA1967 0.67 5.37 0.43 3.72e-7 Breast cancer; TGCT cis rs2663905 0.706 rs2683260 chr15:81385552 A/C cg09888468 chr15:81410853 NA -0.73 -5.51 -0.44 1.96e-7 QT interval (drug interaction); TGCT cis rs7119 0.717 rs12902852 chr15:77809016 C/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg20302342 chr1:156215951 PAQR6 0.36 5.38 0.44 3.56e-7 Tonsillectomy; TGCT cis rs3847687 1.000 rs78233646 chr12:131520170 G/T cg13586425 chr12:131519906 GPR133 -0.33 -5.26 -0.43 6.17e-7 Longevity; TGCT cis rs12422267 0.536 rs11831679 chr12:132609960 C/T cg09764611 chr12:132620959 NA -0.37 -5.68 -0.45 9e-8 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs4824093 0.610 rs12106611 chr22:50242686 G/A cg20569369 chr22:51173646 NA 0.27 4.57 0.38 1.18e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7727544 0.735 rs272894 chr5:131662460 C/T cg24060327 chr5:131705240 SLC22A5 -0.56 -6.38 -0.5 3.2e-9 Blood metabolite levels; TGCT cis rs10791323 0.569 rs2298738 chr11:133715153 G/C cg03690763 chr11:133734501 NA -0.33 -5.07 -0.41 1.44e-6 Childhood ear infection; TGCT cis rs78487399 0.614 rs77389971 chr2:43718084 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -4.52 -0.38 1.41e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2652822 0.530 rs12595312 chr15:63494159 T/C cg12855773 chr15:63363890 TPM1 -0.17 -4.84 -0.4 3.79e-6 Metabolic traits; TGCT cis rs12497850 0.931 rs62262517 chr3:49134914 T/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 3e-7 Parkinson's disease; TGCT cis rs4595586 0.545 rs12828001 chr12:39392208 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs10255878 0.500 rs73398341 chr7:97046433 G/A cg01534613 chr7:96337050 SHFM1 0.31 4.7 0.39 6.9e-6 Adverse response to radiation therapy; TGCT cis rs9811920 0.609 rs7638900 chr3:99670773 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.62 7.25 0.55 3.85e-11 Axial length; TGCT cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg21724239 chr8:58056113 NA 0.33 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.684 rs6756880 chr2:99676991 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs12908161 1.000 rs35630683 chr15:85349231 T/C cg11189052 chr15:85197271 WDR73 0.71 5.87 0.47 3.68e-8 Schizophrenia; TGCT cis rs1878931 0.501 rs9302871 chr16:3415512 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.12 0.54 7.59e-11 Body mass index (adult); TGCT cis rs7103648 1.000 rs7947450 chr11:47429904 G/A cg20307385 chr11:47447363 PSMC3 1.01 12.36 0.74 2.3e-23 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs56104184 0.779 rs4802513 chr19:49357656 T/A cg21252483 chr19:49399788 TULP2 -0.36 -4.5 -0.37 1.53e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6503863 1 rs6503863 chr17:56517034 G/A cg05425664 chr17:57184151 TRIM37 -0.46 -4.45 -0.37 1.91e-5 Intelligence (multi-trait analysis); TGCT cis rs2468186 0.553 rs2465404 chr8:120090859 G/T cg02248809 chr8:120845432 TAF2 -0.44 -4.71 -0.39 6.49e-6 Osteoprotegerin levels; TGCT cis rs477895 1.000 rs1047206 chr11:64089216 C/G cg04317338 chr11:64019027 PLCB3 0.71 5.65 0.45 1.05e-7 Mean platelet volume; TGCT cis rs9467773 0.967 rs9358954 chr6:26531178 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs739496 0.579 rs73426314 chr12:112345056 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs703842 0.575 rs701006 chr12:58106836 C/T cg15848620 chr12:58087721 OS9 0.57 4.75 0.39 5.46e-6 Multiple sclerosis; TGCT cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg10802521 chr3:52805072 NEK4 -0.73 -9.02 -0.63 2.87e-15 Electroencephalogram traits; TGCT cis rs1059312 0.500 rs10734964 chr12:129286486 C/T cg09035930 chr12:129282057 SLC15A4 0.51 7.33 0.55 2.63e-11 Systemic lupus erythematosus; TGCT cis rs7772486 0.597 rs7746618 chr6:146281367 T/C cg23711669 chr6:146136114 FBXO30 -0.73 -6.87 -0.53 2.71e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs73198271 0.960 rs11776546 chr8:8609181 T/G ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.62 -0.38 9.34e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs7772486 0.701 rs2244308 chr6:146213706 C/T cg05347473 chr6:146136440 FBXO30 0.5 4.9 0.4 2.96e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1971762 0.527 rs7976398 chr12:54028862 T/C cg16917193 chr12:54089295 NA 1.06 11.82 0.73 4.57e-22 Height; TGCT cis rs789852 1.000 rs789852 chr3:194327098 T/C cg18000598 chr3:194342907 TMEM44 -0.81 -5.19 -0.42 8.35e-7 QT interval; TGCT cis rs2032447 0.867 rs9295683 chr6:26069495 C/T cg03264133 chr6:25882463 NA -0.62 -5.5 -0.44 2.07e-7 Intelligence (multi-trait analysis); TGCT cis rs7017914 0.967 rs7842851 chr8:71663805 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.49 -4.55 -0.38 1.28e-5 Bone mineral density; TGCT cis rs910316 0.935 rs175448 chr14:75591071 G/A cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.71e-6 Height; TGCT cis rs12615966 1.000 rs9941641 chr2:105384179 A/G cg16465502 chr2:105461796 NA 0.78 5.03 0.41 1.66e-6 Pancreatic cancer; TGCT cis rs1580019 0.961 rs4357201 chr7:32496333 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs12497850 0.864 rs4955410 chr3:49181218 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.55 0.45 1.66e-7 Parkinson's disease; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg01577475 chr2:114033581 PAX8;LOC440839 0.46 4.97 0.41 2.16e-6 Lymphocyte counts; TGCT cis rs1670533 1.000 rs3816474 chr4:1050653 G/A cg19318889 chr4:1322082 MAEA 0.22 4.57 0.38 1.16e-5 Recombination rate (females); TGCT cis rs2153535 0.580 rs6421948 chr6:8531020 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs6088580 0.609 rs2378205 chr20:33110803 C/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs9921192 0.967 rs251737 chr16:4318305 C/T cg00021532 chr16:4324280 TFAP4 0.84 9.87 0.66 2.57e-17 Prostate-specific antigen levels; TGCT cis rs597539 0.616 rs631001 chr11:68642974 C/T cg04772025 chr11:68637568 NA 0.6 6.78 0.52 4.32e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7552404 0.727 rs12093623 chr1:76256232 T/G cg03433033 chr1:76189801 ACADM 0.65 6.6 0.51 1.06e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs137699 0.687 rs4821887 chr22:39756985 C/T cg11247378 chr22:39784982 NA -0.61 -6.73 -0.52 5.53e-10 IgG glycosylation; TGCT cis rs7552404 0.731 rs1770887 chr1:76401812 A/G cg22875332 chr1:76189707 ACADM -0.67 -6.77 -0.52 4.54e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4851254 0.961 rs11692215 chr2:100746573 C/T cg23118464 chr2:100721844 AFF3 0.69 5.03 0.41 1.64e-6 Intelligence (multi-trait analysis); TGCT cis rs4820539 0.932 rs3788349 chr22:23467950 A/G cg14186256 chr22:23484241 RTDR1 0.98 11.82 0.73 4.6e-22 Bone mineral density; TGCT cis rs986417 0.818 rs10139251 chr14:60959958 A/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs71597109 0.681 rs4699261 chr4:102725474 A/G cg14855874 chr4:102712397 BANK1 -0.4 -4.74 -0.39 5.64e-6 Chronic lymphocytic leukemia; TGCT cis rs6484504 0.576 rs441975 chr11:31233351 C/T cg14844989 chr11:31128820 NA -0.23 -4.51 -0.38 1.47e-5 Red blood cell count; TGCT cis rs12579753 0.810 rs1343934 chr12:82123112 G/A cg21231944 chr12:82153410 PPFIA2 -0.35 -4.64 -0.38 8.74e-6 Resting heart rate; TGCT cis rs12575480 0.637 rs73398080 chr11:2094599 G/A cg15541987 chr11:2077307 NA -0.37 -4.47 -0.37 1.71e-5 Pursuit maintenance gain; TGCT trans rs4824093 0.610 rs7410534 chr22:50289925 C/T cg09872104 chr7:134855509 C7orf49 -1.02 -8.52 -0.61 4.42e-14 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9902453 0.845 rs3102558 chr17:28023142 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs9357506 1.000 rs4711849 chr6:46305739 C/T cg21115430 chr6:46460003 NA 0.23 4.67 0.39 7.56e-6 Body mass index; TGCT cis rs3818285 0.610 rs642938 chr10:111633025 A/C cg00817464 chr10:111662876 XPNPEP1 0.32 5.57 0.45 1.51e-7 Superior crus of antihelix expression; TGCT cis rs4975709 0.610 rs4975705 chr5:1860359 T/C cg04156016 chr5:1868137 NA 0.33 4.63 0.38 9.04e-6 Cardiovascular disease risk factors; TGCT cis rs9436747 0.714 rs1751492 chr1:65992625 C/T cg14976592 chr1:65886160 LEPROT;LEPR -0.49 -4.53 -0.38 1.37e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg26818010 chr10:134567672 INPP5A -0.35 -4.45 -0.37 1.86e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9916302 0.706 rs439537 chr17:37734482 T/C cg07936489 chr17:37558343 FBXL20 -0.84 -6.16 -0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs3749237 0.615 rs6792911 chr3:49429856 C/T cg03060546 chr3:49711283 APEH 0.75 8.68 0.61 1.86e-14 Resting heart rate; TGCT cis rs7666738 0.606 rs3846447 chr4:99099907 G/A cg05340658 chr4:99064831 C4orf37 0.43 4.62 0.38 9.29e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs8073060 0.544 rs2626626 chr17:34026717 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1887596 0.672 rs4297560 chr13:27264991 A/T cg01312412 chr13:27282625 NA 0.3 5.36 0.43 3.97e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs8077889 0.703 rs231532 chr17:41945769 C/T cg26893861 chr17:41843967 DUSP3 -1.07 -10.07 -0.67 8.39e-18 Triglycerides; TGCT cis rs7027203 0.576 rs11790754 chr9:96535709 T/G cg13679303 chr9:96623674 NA 0.52 7.49 0.56 1.11e-11 DNA methylation (variation); TGCT cis rs1005277 0.579 rs2749612 chr10:38488610 G/A cg25427524 chr10:38739819 LOC399744 -0.41 -8.54 -0.61 4.04e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2346177 0.967 rs4953374 chr2:46654401 T/C cg26688816 chr2:46740690 ATP6V1E2 -0.46 -5.18 -0.42 8.67e-7 HDL cholesterol; TGCT cis rs7666738 0.830 rs10007872 chr4:99001904 T/C cg18180107 chr4:99064573 C4orf37 0.51 4.68 0.39 7.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2361718 0.500 rs12451697 chr17:78100690 T/A cg09238746 chr17:78121135 EIF4A3 -0.91 -8.85 -0.62 7.48e-15 Yeast infection; TGCT cis rs259282 0.628 rs35946544 chr19:33109983 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.4 0.44 3.31e-7 Schizophrenia; TGCT cis rs7918232 0.782 rs7910168 chr10:27465296 G/A cg14442939 chr10:27389572 ANKRD26 0.82 5.74 0.46 6.98e-8 Breast cancer; TGCT cis rs9733 0.565 rs7524620 chr1:150616699 C/T cg09365446 chr1:150670422 GOLPH3L -0.3 -4.46 -0.37 1.82e-5 Tonsillectomy; TGCT cis rs3008870 1.000 rs12137403 chr1:67437043 C/T cg03991309 chr1:68237761 GNG12 -0.27 -4.66 -0.39 8.08e-6 Lymphocyte percentage of white cells; TGCT cis rs11085466 1.000 rs4399664 chr19:21778026 C/T cg01048962 chr19:21646470 NA -0.59 -4.61 -0.38 9.72e-6 Colorectal or endometrial cancer; TGCT cis rs4851254 0.660 rs17023468 chr2:100694091 A/G cg07810366 chr2:100720526 AFF3 -0.44 -4.63 -0.38 9.06e-6 Intelligence (multi-trait analysis); TGCT cis rs8013055 0.846 rs12893999 chr14:105970842 C/G cg23356831 chr14:105996513 TMEM121 0.41 6.39 0.5 3.04e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs1153858 1.000 rs16952714 chr15:45650358 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7091068 0.518 rs1409337 chr10:95439822 T/C cg20715218 chr10:95462985 C10orf4 0.52 5.46 0.44 2.46e-7 Urinary tract infection frequency; TGCT cis rs7010267 0.740 rs1905786 chr8:119951692 T/C cg17171407 chr8:119960777 TNFRSF11B 0.25 4.44 0.37 2e-5 Total body bone mineral density (age 45-60); TGCT cis rs6750047 0.573 rs162328 chr2:38318688 G/A cg07380506 chr2:38303506 CYP1B1 0.59 5.47 0.44 2.37e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs1670533 1.000 rs10902752 chr4:1056199 C/T cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs9926296 0.656 rs4522419 chr16:89853307 T/C cg03388025 chr16:89894329 SPIRE2 0.35 5.2 0.42 7.97e-7 Vitiligo; TGCT cis rs7178424 0.616 rs1346036 chr15:62137876 G/C cg00456672 chr15:62358751 C2CD4A -0.31 -4.67 -0.39 7.7e-6 Height; TGCT cis rs4803468 0.967 rs3745290 chr19:41890003 C/T cg09537434 chr19:41945824 ATP5SL -0.9 -10.06 -0.67 9.09e-18 Height; TGCT cis rs1005277 0.579 rs2505248 chr10:38459097 A/G cg13531842 chr10:38383804 ZNF37A -0.4 -4.63 -0.38 8.93e-6 Extrinsic epigenetic age acceleration; TGCT cis rs9814567 0.712 rs9838889 chr3:134332311 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg14983838 chr19:29218262 NA 0.83 6.85 0.52 3.07e-10 Methadone dose in opioid dependence; TGCT cis rs6088580 0.634 rs6058073 chr20:33116483 T/C cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs739496 0.527 rs11066079 chr12:112350403 G/T cg10833066 chr12:111807467 FAM109A 0.36 5.41 0.44 3.18e-7 Platelet count; TGCT cis rs904251 0.523 rs1776455 chr6:37482923 A/T cg25019722 chr6:37503610 NA -0.49 -7.47 -0.56 1.28e-11 Cognitive performance; TGCT cis rs7681440 0.647 rs6824979 chr4:90819407 C/G cg20003494 chr4:90757398 SNCA 0.53 4.73 0.39 6.11e-6 Dementia with Lewy bodies; TGCT cis rs9660992 0.710 rs1668867 chr1:205240251 C/T cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs3733585 0.699 rs6449179 chr4:9969117 G/A cg00071950 chr4:10020882 SLC2A9 -0.57 -6.83 -0.52 3.47e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs79387448 0.935 rs7567133 chr2:103253128 C/A cg09003973 chr2:102972529 NA 0.9 5.42 0.44 2.98e-7 Gut microbiota (bacterial taxa); TGCT cis rs9916302 0.555 rs12940193 chr17:37652178 T/G cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs4466137 0.909 rs4466136 chr5:82985576 T/G cg16102102 chr5:83017553 HAPLN1 -0.95 -11.71 -0.72 8.78e-22 Prostate cancer; TGCT cis rs6087990 0.806 rs992472 chr20:31385269 G/T cg13636640 chr20:31349939 DNMT3B 1.1 15.62 0.81 4.5e-31 Ulcerative colitis; TGCT cis rs4938534 0.559 rs1944919 chr11:111259876 A/C cg18316498 chr11:111250196 POU2AF1 0.28 4.86 0.4 3.53e-6 Primary biliary cholangitis; TGCT cis rs826838 1.000 rs1684416 chr12:39130301 G/A cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs3849570 0.961 rs3821548 chr3:81758728 C/G cg07356753 chr3:81810745 GBE1 -0.84 -8.06 -0.59 5.54e-13 Waist circumference;Body mass index; TGCT cis rs3617 0.625 rs2239548 chr3:52854186 A/C cg10802521 chr3:52805072 NEK4 -0.6 -6.89 -0.53 2.46e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4727027 0.901 rs1534197 chr7:148771970 T/C cg23583168 chr7:148888333 NA -0.69 -8.67 -0.61 2.04e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9467711 0.606 rs9358932 chr6:26362705 A/G cg10795676 chr6:26370623 BTN3A2 0.45 4.71 0.39 6.5e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2404602 1.000 rs12594212 chr15:76802014 T/A cg22467129 chr15:76604101 ETFA -0.51 -5.89 -0.47 3.45e-8 Blood metabolite levels; TGCT trans rs7618501 0.633 rs2353579 chr3:50027774 C/T cg21659725 chr3:3221576 CRBN 0.76 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis); TGCT cis rs950776 0.518 rs3813571 chr15:78832792 G/T cg06917634 chr15:78832804 PSMA4 0.96 9.72 0.66 6.01e-17 Sudden cardiac arrest; TGCT cis rs17376456 0.542 rs10476588 chr5:93208330 C/T cg25358565 chr5:93447407 FAM172A -0.81 -6.54 -0.51 1.47e-9 Diabetic retinopathy; TGCT cis rs589448 0.867 rs623853 chr12:69753830 G/A cg14784868 chr12:69753453 YEATS4 0.9 10.55 0.69 5.67e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs751728 0.597 rs767895 chr6:33791463 C/G cg13859433 chr6:33739653 LEMD2 -0.35 -5.78 -0.46 5.75e-8 Crohn's disease; TGCT cis rs769267 0.896 rs7250893 chr19:19625547 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs4891159 0.548 rs10782013 chr18:74128348 C/T cg24786174 chr18:74118243 ZNF516 0.67 13.58 0.77 2.65e-26 Longevity; TGCT cis rs11718455 0.960 rs35711021 chr3:44004791 G/A cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs6733011 0.508 rs6542843 chr2:99533729 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.55 -5.28 -0.43 5.71e-7 Bipolar disorder; TGCT cis rs3617 0.573 rs9880978 chr3:52923251 C/G cg07507251 chr3:52567010 NT5DC2 0.34 4.5 0.37 1.54e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1163251 0.623 rs493427 chr1:120207482 A/T cg19096424 chr1:120255104 PHGDH -0.58 -5.79 -0.46 5.48e-8 Blood metabolite levels; TGCT cis rs894734 0.535 rs7301643 chr12:54325796 G/T cg17708016 chr12:54321992 NA 0.77 6.43 0.5 2.54e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); TGCT cis rs10089 0.904 rs3087889 chr5:127524944 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.79 7.5 0.56 1.05e-11 Ileal carcinoids; TGCT cis rs6095298 0.595 rs720727 chr20:47447960 C/T cg12307787 chr20:48099359 KCNB1 0.44 4.67 0.39 7.75e-6 Intelligence (multi-trait analysis); TGCT cis rs8017423 0.967 rs11627528 chr14:90719697 C/A cg04374321 chr14:90722782 PSMC1 -0.75 -7.4 -0.55 1.79e-11 Mortality in heart failure; TGCT cis rs2455799 0.613 rs4684261 chr3:15796505 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs10484885 0.887 rs17764308 chr6:90602268 T/C cg13799429 chr6:90582589 CASP8AP2 -0.43 -4.46 -0.37 1.8e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9905704 0.647 rs33922512 chr17:57114148 C/G cg12560992 chr17:57184187 TRIM37 -0.62 -5.52 -0.44 1.9e-7 Testicular germ cell tumor; TGCT cis rs17030434 1.000 rs12646758 chr4:154731625 A/G cg14289246 chr4:154710475 SFRP2 -0.89 -6.94 -0.53 1.97e-10 Electrocardiographic conduction measures; TGCT cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.97 10.6 0.69 4.33e-19 Intelligence (multi-trait analysis); TGCT cis rs55883249 0.957 rs17453675 chr2:9754407 A/G cg23886495 chr2:9695866 ADAM17 0.79 4.66 0.39 8.09e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs7927592 0.763 rs596494 chr11:68251054 T/G cg16797656 chr11:68205561 LRP5 0.26 4.46 0.37 1.79e-5 Total body bone mineral density; TGCT cis rs7267979 0.932 rs372678 chr20:25465248 G/A cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7714584 1.000 rs59321715 chr5:150313480 C/A cg22134413 chr5:150180641 NA 1.13 7.97 0.58 8.75e-13 Crohn's disease; TGCT trans rs916888 0.610 rs199530 chr17:44836653 C/T cg22433210 chr17:43662623 NA -0.86 -7.23 -0.54 4.29e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12548874 0.607 rs12543492 chr8:95891843 C/A cg13393036 chr8:95962371 TP53INP1 -0.51 -6.24 -0.49 6.48e-9 Hemoglobin concentration; TGCT cis rs422249 0.512 rs99780 chr11:61596633 C/T cg20584555 chr11:61717780 BEST1 -0.23 -4.49 -0.37 1.6e-5 Trans fatty acid levels; TGCT cis rs2295359 1.000 rs11209006 chr1:67619259 T/G cg03340356 chr1:67600835 NA 0.36 4.55 0.38 1.24e-5 Psoriasis; TGCT cis rs6500602 0.702 rs4786493 chr16:4500122 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.28 5.23 0.43 6.91e-7 Schizophrenia; TGCT cis rs13256369 0.760 rs7839473 chr8:8575836 C/T cg06671706 chr8:8559999 CLDN23 0.35 4.62 0.38 9.35e-6 Obesity-related traits; TGCT trans rs7824557 0.527 rs57629785 chr8:11235150 C/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.42e-10 Retinal vascular caliber; TGCT cis rs992157 0.835 rs13031757 chr2:219151926 T/C cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT cis rs4888262 0.508 rs4887779 chr16:74647795 A/G cg01733217 chr16:74700730 RFWD3 -0.74 -7.46 -0.56 1.28e-11 Testicular germ cell tumor; TGCT cis rs4746822 0.539 rs10998646 chr10:70976702 G/T cg14418922 chr10:70824840 NA -0.27 -4.58 -0.38 1.1e-5 Glycemic traits (pregnancy); TGCT cis rs7666738 0.830 rs35685312 chr4:98858521 G/A cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7312933 0.645 rs11181404 chr12:42683840 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.57 5.27 0.43 5.87e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg13395646 chr4:1353034 KIAA1530 0.4 4.98 0.41 2.1e-6 Obesity-related traits; TGCT cis rs9303401 0.659 rs7224276 chr17:56897827 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs9291683 0.588 rs35866697 chr4:10018604 C/A cg00071950 chr4:10020882 SLC2A9 0.75 10.2 0.68 4.17e-18 Bone mineral density; TGCT cis rs7607369 0.580 rs17573724 chr2:219652141 T/A cg02176678 chr2:219576539 TTLL4 -0.45 -5.86 -0.47 3.89e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs4455778 0.665 rs7804817 chr7:49071509 C/T cg26309511 chr7:48887640 NA 0.47 5.33 0.43 4.56e-7 Lung cancer in never smokers; TGCT cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs3096299 0.967 rs2911255 chr16:89487137 C/T cg02187348 chr16:89574699 SPG7 0.47 4.56 0.38 1.2e-5 Multiple myeloma (IgH translocation); TGCT cis rs2282802 0.685 rs6580515 chr5:139698110 A/C cg01081189 chr5:139537190 NA -0.27 -4.9 -0.4 2.87e-6 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.609 rs6060948 chr20:30376393 C/G cg13852791 chr20:30311386 BCL2L1 0.83 8.16 0.59 3.22e-13 Mean corpuscular hemoglobin; TGCT trans rs877282 0.945 rs71489301 chr10:770191 A/G cg22713356 chr15:30763199 NA 1.26 10.48 0.69 8.73e-19 Uric acid levels; TGCT cis rs77972916 0.536 rs7562101 chr2:43592756 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.02 -0.48 1.8e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs896854 0.902 rs726816 chr8:95968413 T/G cg16049864 chr8:95962084 TP53INP1 -0.75 -10.57 -0.69 5.23e-19 Type 2 diabetes; TGCT cis rs151997 0.925 rs27270 chr5:50183712 A/G cg06027927 chr5:50259733 NA -0.45 -4.63 -0.38 9.02e-6 Callous-unemotional behaviour; TGCT cis rs4851266 1.000 rs13013169 chr2:100814087 A/C cg22139774 chr2:100720529 AFF3 -0.38 -5.53 -0.44 1.81e-7 Educational attainment; TGCT cis rs12682352 0.579 rs7006589 chr8:8668486 A/G cg08975724 chr8:8085496 FLJ10661 0.53 4.74 0.39 5.87e-6 Neuroticism; TGCT cis rs56104184 0.725 rs4347731 chr19:49385154 A/G cg17863274 chr19:49399704 TULP2 -0.54 -7.2 -0.54 5.19e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9902453 0.967 rs1042173 chr17:28525011 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs7666738 0.861 rs5010991 chr4:98972179 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4699052 0.963 rs6849319 chr4:104192742 G/C cg16532752 chr4:104119610 CENPE -0.55 -4.97 -0.41 2.19e-6 Testicular germ cell tumor; TGCT cis rs7226408 0.857 rs11081988 chr18:34697833 T/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6570726 0.577 rs399502 chr6:145805874 A/G cg13319975 chr6:146136371 FBXO30 -0.64 -5.69 -0.46 8.55e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7572733 0.555 rs2341778 chr2:198776546 G/A cg00792783 chr2:198669748 PLCL1 -0.56 -5.11 -0.42 1.21e-6 Dermatomyositis; TGCT cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg13397359 chr6:42928475 GNMT -0.72 -6.48 -0.5 1.93e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12048904 0.964 rs12027668 chr1:101330984 G/A cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 4.62 0.38 9.44e-6 Multiple sclerosis; TGCT cis rs7044106 0.791 rs10984998 chr9:123481516 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 7.05 0.53 1.11e-10 Hip circumference adjusted for BMI; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg01171360 chr6:293285 DUSP22 -0.78 -7.87 -0.58 1.47e-12 Menopause (age at onset); TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg18538332 chr22:24372958 LOC391322 -1.02 -13.18 -0.76 2.42e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7412746 0.611 rs2280627 chr1:150935872 A/G cg04414720 chr1:150670196 GOLPH3L 0.38 4.5 0.37 1.52e-5 Melanoma; TGCT cis rs4665809 0.680 rs3955310 chr2:26290828 T/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg22166914 chr1:53195759 ZYG11B -0.4 -6.94 -0.53 1.89e-10 Monocyte count; TGCT cis rs6750795 0.569 rs1667308 chr2:232406344 T/C cg19187155 chr2:232395269 NMUR1 0.41 4.68 0.39 7.29e-6 Height; TGCT cis rs752010 0.808 rs7529858 chr1:42086606 G/C cg06885757 chr1:42089581 HIVEP3 0.25 4.56 0.38 1.23e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs9916302 0.904 rs7503705 chr17:37669704 A/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.88 -0.4 3.2e-6 Glomerular filtration rate (creatinine); TGCT cis rs2456568 0.771 rs8181530 chr11:93638678 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.09e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3008870 0.917 rs12044492 chr1:67461667 T/C cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs6912958 0.754 rs4587143 chr6:88292291 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT trans rs7819412 0.806 rs10113808 chr8:10926892 C/A cg06636001 chr8:8085503 FLJ10661 -0.73 -6.72 -0.52 5.88e-10 Triglycerides; TGCT cis rs35883536 0.588 rs114540631 chr1:101101249 A/G cg06223162 chr1:101003688 GPR88 0.33 5.4 0.44 3.28e-7 Monocyte count; TGCT cis rs514406 0.621 rs2003250 chr1:53196666 T/C cg25767906 chr1:53392781 SCP2 0.44 4.79 0.4 4.68e-6 Monocyte count; TGCT cis rs514406 0.607 rs1930305 chr1:53195481 G/T cg25767906 chr1:53392781 SCP2 0.44 4.79 0.4 4.68e-6 Monocyte count; TGCT cis rs57221529 0.766 rs56216231 chr5:581193 G/A cg09021430 chr5:549028 NA -0.37 -5.35 -0.43 4.16e-7 Lung disease severity in cystic fibrosis; TGCT cis rs9733 0.596 rs12072339 chr1:150686099 A/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs11247915 0.600 rs61775118 chr1:26659692 C/T cg25392287 chr1:26333318 NA 0.22 4.69 0.39 7.01e-6 Obesity-related traits; TGCT cis rs7086627 0.515 rs10887899 chr10:82210214 G/A cg00277334 chr10:82204260 NA -0.54 -8.46 -0.6 6.41e-14 Post bronchodilator FEV1; TGCT cis rs3125734 0.633 rs6479792 chr10:63983264 T/G cg19640130 chr10:64028056 RTKN2 -0.39 -5.11 -0.42 1.19e-6 Rheumatoid arthritis; TGCT cis rs11642862 1.000 rs113454775 chr16:30809534 A/G cg02466173 chr16:30829666 NA -0.39 -4.64 -0.38 8.67e-6 Tonsillectomy; TGCT cis rs904251 0.523 rs2797796 chr6:37480886 T/C cg08126542 chr6:37504118 NA -0.44 -6.51 -0.5 1.71e-9 Cognitive performance; TGCT cis rs13242816 1.000 rs17138714 chr7:116114274 C/T cg16553024 chr7:116138462 CAV2 -0.44 -5.05 -0.41 1.54e-6 P wave duration; TGCT cis rs2404602 0.692 rs3816266 chr15:76993835 T/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs7336332 0.598 rs74183666 chr13:28007765 A/T cg22138327 chr13:27999177 GTF3A 0.83 6.51 0.5 1.67e-9 Weight; TGCT cis rs6912958 0.967 rs6914299 chr6:88149176 T/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.74 -0.39 5.79e-6 Monocyte percentage of white cells; TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg27535305 chr1:53392650 SCP2 -0.24 -4.73 -0.39 5.98e-6 Monocyte count; TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg11965913 chr1:205819406 PM20D1 0.51 7.19 0.54 5.34e-11 Menarche (age at onset); TGCT cis rs7809950 0.954 rs2712193 chr7:107125885 A/C cg23024343 chr7:107201750 COG5 -0.34 -5.45 -0.44 2.58e-7 Coronary artery disease; TGCT cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs2075371 0.796 rs35440439 chr7:134006094 C/T cg11752832 chr7:134001865 SLC35B4 0.72 6.55 0.51 1.35e-9 Mean platelet volume; TGCT cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.79e-6 Obesity-related traits; TGCT cis rs1670533 0.818 rs6835141 chr4:1070140 G/T cg27284194 chr4:1044797 NA 0.7 6.11 0.48 1.17e-8 Recombination rate (females); TGCT cis rs7296418 0.675 rs1879379 chr12:123727443 G/A cg00376283 chr12:123451042 ABCB9 0.73 6.5 0.5 1.75e-9 Platelet count; TGCT cis rs2468186 0.524 rs2450064 chr8:120097144 A/G cg02248809 chr8:120845432 TAF2 -0.45 -4.83 -0.4 3.99e-6 Osteoprotegerin levels; TGCT cis rs4595586 0.505 rs76485055 chr12:39358294 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs6988636 1.000 rs7002021 chr8:124185250 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs7772486 0.727 rs2235481 chr6:146056848 T/C cg23711669 chr6:146136114 FBXO30 -0.73 -6.61 -0.51 1.04e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4148883 0.675 rs116265877 chr4:100096896 G/A cg12011299 chr4:100065546 ADH4 0.39 5.85 0.47 4.03e-8 Alcohol dependence; TGCT cis rs2688608 0.592 rs7909544 chr10:75484004 G/C cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs8077889 0.917 rs1859048 chr17:41892039 A/C cg26893861 chr17:41843967 DUSP3 -1.1 -13.53 -0.77 3.52e-26 Triglycerides; TGCT cis rs9926296 0.605 rs12599180 chr16:89839306 C/T cg27121462 chr16:89883253 FANCA -0.73 -7.85 -0.58 1.63e-12 Vitiligo; TGCT cis rs2997447 0.706 rs17184898 chr1:26447870 A/T cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT cis rs7945705 0.902 rs10769979 chr11:9010659 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.15 0.42 9.85e-7 Hemoglobin concentration; TGCT cis rs4665809 1.000 rs1030730 chr2:26284143 T/C cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT trans rs797680 0.856 rs2031225 chr1:93786714 A/G cg27528825 chr2:159282178 CCDC148 0.33 6.67 0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs8017423 1.000 rs769044 chr14:90671138 A/G cg04374321 chr14:90722782 PSMC1 0.74 7.7 0.57 3.71e-12 Mortality in heart failure; TGCT cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg11644478 chr21:40555479 PSMG1 0.98 10.31 0.68 2.21e-18 Cognitive function; TGCT trans rs1005277 0.579 rs2505197 chr10:38393310 T/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT trans rs2688608 0.592 rs10762560 chr10:75495405 T/G cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs116161686 0.500 rs55871867 chr1:210051029 A/G cg23283495 chr1:209979779 IRF6 0.61 4.81 0.4 4.3e-6 Coronary artery disease; TGCT cis rs2380220 0.678 rs4308568 chr6:96009525 A/C cg04719120 chr6:96025338 MANEA -0.7 -5.35 -0.43 4.16e-7 Behavioural disinhibition (generation interaction); TGCT cis rs9393777 0.513 rs9393739 chr6:26646966 T/G cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs861020 1.000 rs861020 chr1:209977111 A/G cg05527609 chr1:210001259 C1orf107 0.89 7.18 0.54 5.65e-11 Orofacial clefts; TGCT cis rs4925325 1.000 rs4925325 chr20:60514224 G/A cg12751644 chr20:60527061 NA 0.49 6.32 0.49 4.26e-9 Obesity-related traits; TGCT cis rs4808199 0.948 rs2074301 chr19:19381715 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.22 0.42 7.2e-7 Nonalcoholic fatty liver disease; TGCT cis rs71636778 0.509 rs17162387 chr1:27293356 T/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT trans rs1814175 0.781 rs2866734 chr11:49886338 A/G cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs9814567 0.806 rs9841371 chr3:134320765 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs12188164 0.930 rs72717440 chr5:449701 A/T cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs9560113 0.960 rs9560101 chr13:112173798 G/A cg14154082 chr13:112174009 NA 0.34 4.67 0.39 7.79e-6 Menarche (age at onset); TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg01577475 chr2:114033581 PAX8;LOC440839 -0.45 -4.93 -0.41 2.54e-6 Lymphocyte counts; TGCT cis rs12216125 0.801 rs56107510 chr6:25987436 C/A cg17042849 chr6:26104293 HIST1H4C -0.74 -6.55 -0.51 1.41e-9 Iron status biomarkers; TGCT cis rs9807989 0.507 rs7584093 chr2:102997721 C/T cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs9659323 1.000 rs56897173 chr1:119515732 G/A cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.4e-6 Body mass index; TGCT trans rs9388451 0.559 rs1777210 chr6:126098916 T/G cg05039488 chr6:79577232 IRAK1BP1 -0.79 -9.13 -0.63 1.57e-15 Brugada syndrome; TGCT cis rs4665809 0.941 rs11126336 chr2:26245931 C/T cg22920501 chr2:26401640 FAM59B -0.71 -6.23 -0.49 6.65e-9 Gut microbiome composition (summer); TGCT cis rs2201841 0.960 rs114173254 chr1:67709650 G/A cg25131922 chr1:68698529 GPR177 0.46 4.95 0.41 2.34e-6 Ulcerative colitis;Psoriasis;Crohn's disease; TGCT cis rs7267979 0.933 rs2258728 chr20:25276343 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs2932538 0.885 rs6661642 chr1:113090109 T/C cg22162597 chr1:113214053 CAPZA1 0.27 5.89 0.47 3.46e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg13695892 chr22:41940480 POLR3H 0.79 7.83 0.58 1.85e-12 Vitiligo; TGCT cis rs25422 0.887 rs9320666 chr6:118989181 C/T cg21191810 chr6:118973309 C6orf204 -0.34 -4.65 -0.39 8.45e-6 Renal cell carcinoma; TGCT cis rs9486719 1.000 rs67996804 chr6:96884387 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT trans rs4332037 0.539 rs11762636 chr7:2061111 C/A cg10840412 chr1:235813424 GNG4 0.94 6.84 0.52 3.21e-10 Bipolar disorder; TGCT cis rs886126 1.000 rs876027 chr12:111678458 A/T cg10833066 chr12:111807467 FAM109A 0.32 5.08 0.41 1.37e-6 Coronary heart disease; TGCT cis rs46522 0.585 rs79049364 chr17:47014991 T/A cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.06e-8 Coronary heart disease; TGCT cis rs17711722 0.727 rs35850374 chr7:65357776 A/G cg00343986 chr7:65444356 GUSB 0.26 6.11 0.48 1.18e-8 Calcium levels; TGCT cis rs6089829 0.962 rs2314130 chr20:61665129 G/T cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs1218582 0.772 rs10908448 chr1:154882544 A/G cg24250549 chr1:154909240 PMVK -0.62 -6.09 -0.48 1.32e-8 Prostate cancer; TGCT cis rs1541995 1.000 rs4984458 chr15:96392021 A/T cg00882281 chr15:96346592 NA 0.29 4.68 0.39 7.42e-6 Photic sneeze reflex; TGCT cis rs4478037 0.749 rs72856153 chr3:33111182 T/G cg19404215 chr3:33155277 CRTAP 1.26 7.36 0.55 2.18e-11 Major depressive disorder; TGCT cis rs66573146 1.000 rs55688389 chr4:7030689 C/G cg01220768 chr4:7056774 TADA2B 0.43 5.04 0.41 1.6e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9303401 0.614 rs35308719 chr17:57163501 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs12220238 0.722 rs10740441 chr10:76410225 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.58 -4.51 -0.38 1.48e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3820928 0.605 rs4281898 chr2:227855493 A/C cg11843606 chr2:227700838 RHBDD1 -0.51 -4.71 -0.39 6.41e-6 Pulmonary function; TGCT cis rs1008375 1.000 rs3815414 chr4:17606659 A/G cg10189774 chr4:17578691 LAP3 -0.59 -5.27 -0.43 5.81e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs67478160 0.643 rs7147171 chr14:104264857 G/A cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs9329289 0.510 rs11251283 chr10:2555784 C/G cg07014206 chr10:2547000 NA -0.28 -4.64 -0.38 8.72e-6 Age-related hearing impairment; TGCT cis rs12477438 0.798 rs4622780 chr2:99631760 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.31 -0.6 1.43e-13 Chronic sinus infection; TGCT cis rs1372520 0.684 rs2737030 chr4:90710099 C/T cg15133208 chr4:90757351 SNCA -0.5 -5.92 -0.47 2.9e-8 Neuroticism; TGCT cis rs6977660 0.507 rs72591450 chr7:19775480 A/G cg07541023 chr7:19748670 TWISTNB 1.01 6.55 0.51 1.39e-9 Thyroid stimulating hormone; TGCT trans rs2727020 0.619 rs1164665 chr11:49295630 T/C cg03929089 chr4:120376271 NA 0.67 6.89 0.53 2.44e-10 Coronary artery disease; TGCT cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4372836 0.543 rs6747852 chr2:29009840 A/T cg09522027 chr2:28974177 PPP1CB -0.77 -7.46 -0.56 1.33e-11 Body mass index; TGCT cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1205863 0.607 rs9394412 chr6:11931887 A/C cg07106625 chr6:11870215 NA 0.47 4.77 0.39 5.17e-6 Disc degeneration (lumbar); TGCT cis rs7647973 0.848 rs4955426 chr3:49143438 C/A cg07636037 chr3:49044803 WDR6 0.81 6.17 0.48 8.81e-9 Menarche (age at onset); TGCT cis rs9379774 0.517 rs72840524 chr6:25651664 T/C cg11165035 chr6:26601993 NA 0.23 4.5 0.37 1.57e-5 Coronary artery disease; TGCT cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs6570726 0.791 rs1509213 chr6:145783360 G/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.67 -0.39 7.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg18402987 chr7:1209562 NA 0.67 5.94 0.47 2.72e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6674176 0.611 rs2486011 chr1:44381246 C/T cg12908607 chr1:44402522 ARTN -0.73 -4.61 -0.38 9.87e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs10504229 0.775 rs17805110 chr8:58161439 C/G cg24829409 chr8:58192753 C8orf71 0.6 5.3 0.43 5.2e-7 Developmental language disorder (linguistic errors); TGCT cis rs7917772 0.507 rs2778036 chr10:104485725 G/A cg05855489 chr10:104503620 C10orf26 -0.72 -5.92 -0.47 2.94e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4746059 0.545 rs7081273 chr10:72457038 C/G cg03087610 chr10:71892362 AIFM2 0.5 4.63 0.38 9.26e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6674970 1.000 rs6656450 chr1:151089602 A/T cg00003202 chr1:151319512 RFX5 -0.51 -4.46 -0.37 1.84e-5 Childhood ear infection; TGCT cis rs1729951 0.575 rs361242 chr3:136698330 C/G cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.62e-9 Neuroticism; TGCT cis rs7819412 0.545 rs11985603 chr8:10918393 G/A cg21775007 chr8:11205619 TDH -0.49 -4.87 -0.4 3.35e-6 Triglycerides; TGCT trans rs11088226 0.681 rs1015048 chr21:33949306 T/C cg09050820 chr6:167586206 TCP10L2 0.76 7.31 0.55 2.88e-11 Gastritis; TGCT cis rs17376456 0.877 rs17083455 chr5:93446380 A/C cg25358565 chr5:93447407 FAM172A 0.9 8.26 0.6 1.9e-13 Diabetic retinopathy; TGCT cis rs2777491 0.915 rs7178634 chr15:41634587 A/G cg18705301 chr15:41695430 NDUFAF1 -0.74 -10.4 -0.68 1.37e-18 Ulcerative colitis; TGCT cis rs1005277 0.540 rs2224248 chr10:38451886 A/G cg13531842 chr10:38383804 ZNF37A -0.39 -4.64 -0.38 8.78e-6 Extrinsic epigenetic age acceleration; TGCT cis rs651907 0.557 rs11712748 chr3:101383562 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.24 0.43 6.66e-7 Colorectal cancer; TGCT cis rs4862750 0.914 rs11943333 chr4:187872455 A/G cg03452623 chr4:187889614 NA -0.36 -5.19 -0.42 8.19e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9913156 0.789 rs55999196 chr17:4600655 A/G cg00122941 chr17:4613640 ARRB2 0.88 7.63 0.57 5.46e-12 Lymphocyte counts; TGCT trans rs9929218 0.529 rs8059194 chr16:68749663 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.57 7.25 0.55 3.99e-11 Colorectal cancer; TGCT cis rs10927875 0.615 rs10927886 chr1:16339313 C/G cg22431228 chr1:16359049 CLCNKA 0.28 5.99 0.47 2.09e-8 Dilated cardiomyopathy; TGCT cis rs6815814 0.950 rs66819621 chr4:38819403 A/G cg02016764 chr4:38805732 TLR1 -0.34 -5.4 -0.44 3.26e-7 Breast cancer; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.9 0.4 2.98e-6 Lymphocyte counts; TGCT cis rs10875746 0.768 rs10875724 chr12:48420253 C/A cg20731937 chr12:48336164 NA 0.72 6.1 0.48 1.23e-8 Longevity (90 years and older); TGCT cis rs7666738 0.830 rs115279324 chr4:99042114 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2180341 0.960 rs7753913 chr6:127671296 A/G cg27446573 chr6:127587934 RNF146 1.21 10.87 0.7 9.57e-20 Breast cancer; TGCT cis rs11190604 0.767 rs7078070 chr10:102166415 A/C cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4851254 0.618 rs13033732 chr2:100644797 A/G cg07810366 chr2:100720526 AFF3 -0.46 -4.64 -0.38 8.78e-6 Intelligence (multi-trait analysis); TGCT cis rs13118159 0.509 rs7681872 chr4:1376735 G/A cg05025164 chr4:1340916 KIAA1530 0.69 5.63 0.45 1.13e-7 Longevity; TGCT cis rs11031096 0.678 rs11031184 chr11:4186192 C/T cg18678763 chr11:4115507 RRM1 -0.38 -4.87 -0.4 3.35e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs8038465 0.904 rs12594627 chr15:73986264 G/T cg15420318 chr15:73925796 NPTN 0.52 4.59 0.38 1.08e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7726839 0.540 rs61580655 chr5:597564 A/G cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs17376456 0.877 rs10062711 chr5:93348659 G/A cg21475434 chr5:93447410 FAM172A 0.6 4.74 0.39 5.71e-6 Diabetic retinopathy; TGCT cis rs4862750 0.872 rs13101380 chr4:187894744 G/A cg11301795 chr4:187892539 NA -0.34 -5.02 -0.41 1.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10744422 0.925 rs2061098 chr12:123349410 T/C cg25930673 chr12:123319894 HIP1R -0.86 -4.86 -0.4 3.47e-6 Schizophrenia; TGCT cis rs7216064 1.000 rs7216064 chr17:65898809 G/A cg12091567 chr17:66097778 LOC651250 -0.81 -6.15 -0.48 9.71e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4566357 1.000 rs6705989 chr2:227923320 G/A cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs8017423 0.605 rs4904676 chr14:90819220 G/A cg04374321 chr14:90722782 PSMC1 -0.58 -5.75 -0.46 6.5e-8 Mortality in heart failure; TGCT cis rs9291683 0.526 rs7695555 chr4:10001656 T/C cg11266682 chr4:10021025 SLC2A9 0.62 7.88 0.58 1.41e-12 Bone mineral density; TGCT cis rs10501293 1.000 rs6485394 chr11:43080041 A/C cg03447554 chr11:43094025 NA -0.46 -6.6 -0.51 1.06e-9 Cognitive performance; TGCT cis rs9942416 0.617 rs72633979 chr5:74990178 A/T cg02573091 chr5:74908125 NA 0.41 4.62 0.38 9.62e-6 Age-related disease endophenotypes; TGCT cis rs9807989 0.708 rs6543124 chr2:102987459 T/A cg09003973 chr2:102972529 NA 0.63 5.48 0.44 2.26e-7 Asthma; TGCT cis rs733175 0.857 rs751092 chr4:10005897 C/T cg11266682 chr4:10021025 SLC2A9 0.52 4.5 0.37 1.55e-5 Psychosis and Alzheimer's disease; TGCT cis rs4780401 0.609 rs8047190 chr16:11807097 T/C cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs6088590 0.542 rs6059956 chr20:33220070 A/G cg08999081 chr20:33150536 PIGU 0.26 5.14 0.42 1.04e-6 Coronary artery disease; TGCT trans rs1814175 0.817 rs28502006 chr11:50049930 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs763121 0.853 rs2413545 chr22:39092524 C/T cg06022373 chr22:39101656 GTPBP1 0.78 7.67 0.57 4.44e-12 Menopause (age at onset); TGCT cis rs1215050 0.791 rs6532702 chr4:98766641 C/T cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1395 0.744 rs72817536 chr2:27497548 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.64 6.98 0.53 1.54e-10 Blood metabolite levels; TGCT cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg03806693 chr22:41940476 POLR3H 1.15 12.98 0.76 7.24e-25 Vitiligo; TGCT cis rs7044106 0.664 rs7861679 chr9:123375589 A/G cg14255062 chr9:123606675 PSMD5;LOC253039 -0.19 -4.52 -0.38 1.43e-5 Hip circumference adjusted for BMI; TGCT cis rs2963155 0.518 rs1438732 chr5:142756266 G/C cg17617527 chr5:142782415 NR3C1 0.84 5.51 0.44 1.99e-7 Breast cancer; TGCT cis rs6460942 0.915 rs79232243 chr7:12459494 G/A cg06484146 chr7:12443880 VWDE -0.57 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT cis rs4563143 0.663 rs10406794 chr19:29228056 C/T cg14983838 chr19:29218262 NA 0.79 7.44 0.56 1.48e-11 Methadone dose in opioid dependence; TGCT cis rs2282802 0.685 rs2116790 chr5:139654115 G/A cg01081189 chr5:139537190 NA 0.28 5.15 0.42 9.75e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs11935078 chr4:99010476 T/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7714584 1.000 rs11743488 chr5:150279218 A/G cg22134413 chr5:150180641 NA 1.14 8.32 0.6 1.33e-13 Crohn's disease; TGCT cis rs5750830 0.594 rs5757648 chr22:39775156 G/A cg01416388 chr22:39784598 NA -0.59 -5.8 -0.46 5.09e-8 Intelligence (multi-trait analysis); TGCT cis rs2677744 0.688 rs2238340 chr15:91447686 G/A cg23684204 chr15:91497937 RCCD1 0.33 4.61 0.38 1e-5 Attention deficit hyperactivity disorder; TGCT cis rs7172809 0.573 rs7496431 chr15:77452054 T/C cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs12579753 0.917 rs12822036 chr12:82183009 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs2334880 0.678 rs66778248 chr16:71451424 A/G cg06353428 chr16:71660113 MARVELD3 -1.22 -7.81 -0.57 2.05e-12 Malaria; TGCT cis rs2996428 0.709 rs7527973 chr1:3704041 C/T cg17848003 chr1:3704513 LRRC47 0.16 4.49 0.37 1.59e-5 Red cell distribution width; TGCT cis rs4927850 0.957 rs4927851 chr3:195751853 A/G cg02975922 chr3:195473998 MUC4 -0.24 -5.47 -0.44 2.4e-7 Pancreatic cancer; TGCT cis rs10504229 1.000 rs76270388 chr8:58195605 T/A cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs9527 0.568 rs12772775 chr10:104702999 C/A cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs2730245 0.569 rs1188955 chr7:158690866 A/G cg24397884 chr7:158709396 WDR60 0.36 4.57 0.38 1.17e-5 Height; TGCT cis rs13242816 1.000 rs34234085 chr7:116114066 G/A cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs35146811 0.735 rs1636978 chr7:99813912 G/A cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs13191362 0.935 rs35942036 chr6:163163297 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.14 9.38 0.64 4.1e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs637571 0.522 rs3016868 chr11:65764383 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.67 6.69 0.51 6.89e-10 Eosinophil percentage of white cells; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg15242686 chr22:24348715 GSTTP1 0.42 5.68 0.45 9.1e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7523273 0.526 rs2952 chr1:208049077 C/T cg22525895 chr1:207977042 MIR29B2 0.34 5.49 0.44 2.2e-7 Schizophrenia; TGCT cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg27286337 chr10:134555280 INPP5A 0.39 4.82 0.4 4.1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6714710 0.603 rs35255677 chr2:98567820 G/A cg26665480 chr2:98280029 ACTR1B 0.63 5.99 0.47 2.13e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs1997103 1.000 rs6593237 chr7:55411015 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs428668 0.523 rs10060607 chr5:150679304 A/C cg14086364 chr5:150678334 SLC36A3 0.17 4.55 0.38 1.28e-5 Skin aging (microtopography measurement); TGCT cis rs6088590 1.000 rs6119512 chr20:33306904 T/C cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT cis rs1635 0.655 rs59598126 chr6:28303600 A/C cg15743358 chr6:28303923 ZNF323 -1.28 -6.27 -0.49 5.57e-9 Schizophrenia; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg02953382 chr22:24373134 LOC391322 0.78 6.6 0.51 1.07e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7916697 0.626 rs3858144 chr10:70011354 A/G cg25926515 chr10:70321889 TET1 0.35 4.46 0.37 1.84e-5 Optic disc area; TGCT cis rs4820539 1.000 rs4822361 chr22:23482718 A/G cg21100191 chr22:23484243 RTDR1 -0.89 -10.78 -0.7 1.61e-19 Bone mineral density; TGCT cis rs9894429 0.789 rs6565611 chr17:79598319 T/C cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs644148 1.000 rs644148 chr19:44970935 T/G cg15540054 chr19:45004280 ZNF180 -0.59 -5.21 -0.42 7.8e-7 Personality dimensions; TGCT cis rs67311347 1.000 rs977652 chr3:40479169 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT trans rs9951602 0.512 rs12458828 chr18:76648522 C/T cg02800362 chr5:177631904 HNRNPAB -1.17 -12.42 -0.74 1.64e-23 Obesity-related traits; TGCT cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg06634786 chr22:41940651 POLR3H -0.87 -8.23 -0.59 2.17e-13 Vitiligo; TGCT cis rs11864453 0.514 rs2269918 chr16:72134831 C/A cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs4563143 0.514 rs112651366 chr19:29299704 A/T cg14983838 chr19:29218262 NA 0.71 5.18 0.42 8.75e-7 Methadone dose in opioid dependence; TGCT cis rs6570726 0.764 rs367065 chr6:145882309 T/G cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Vitiligo; TGCT cis rs2013441 1.000 rs34712254 chr17:20049308 C/T cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs4663866 1.000 rs4663300 chr2:239181491 T/C cg17283117 chr2:239148619 HES6 1.0 4.6 0.38 1.03e-5 Irritable bowel syndrome; TGCT trans rs8073060 0.586 rs2428464 chr17:34021994 C/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.0 8.22 0.59 2.32e-13 Platelet count; TGCT cis rs6684514 1.000 rs12027741 chr1:156248148 T/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs707040 1.000 rs10202750 chr2:155233823 T/C cg18104148 chr2:154337490 NA 0.19 4.57 0.38 1.17e-5 Sudden cardiac arrest; TGCT cis rs2228479 0.850 rs74251570 chr16:89910068 C/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs7017914 0.967 rs7001162 chr8:71587470 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs56104184 0.723 rs73063515 chr19:49407715 C/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs11690935 0.959 rs4668412 chr2:172619770 A/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs1372520 0.577 rs748849 chr4:90734961 G/A cg15133208 chr4:90757351 SNCA -0.53 -6.29 -0.49 4.94e-9 Neuroticism; TGCT cis rs2354432 0.556 rs4424557 chr1:146871119 A/G cg25205988 chr1:146714368 CHD1L 1.32 5.88 0.47 3.62e-8 Mitochondrial DNA levels; TGCT cis rs1862618 0.671 rs173763 chr5:56225418 G/A cg20203395 chr5:56204925 C5orf35 -0.53 -4.92 -0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs2797160 0.515 rs4897149 chr6:125980018 G/T cg05901451 chr6:126070800 HEY2 0.63 5.31 0.43 4.85e-7 Endometrial cancer; TGCT cis rs2549003 1.000 rs2070725 chr5:131821788 C/T cg21138405 chr5:131827807 IRF1 0.19 4.79 0.39 4.76e-6 Asthma (sex interaction); TGCT cis rs2439831 1.000 rs2245908 chr15:43731454 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs1461503 0.966 rs10892939 chr11:122841959 T/C cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs7727544 0.669 rs113823725 chr5:131563501 C/G cg24060327 chr5:131705240 SLC22A5 -0.55 -5.12 -0.42 1.15e-6 Blood metabolite levels; TGCT cis rs3780378 0.875 rs2031906 chr9:5087495 C/T cg02405213 chr9:5042618 JAK2 -0.64 -8.72 -0.62 1.51e-14 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs854765 0.693 rs8080061 chr17:17776389 C/T cg09796270 chr17:17721594 SREBF1 -0.24 -4.78 -0.39 4.77e-6 Total body bone mineral density; TGCT cis rs9527 0.615 rs9733635 chr10:104711940 G/A cg15744005 chr10:104629667 AS3MT -0.45 -5.24 -0.43 6.77e-7 Arsenic metabolism; TGCT cis rs9457247 0.967 rs1211447 chr6:167381979 C/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs1372520 0.684 rs356162 chr4:90697157 T/C cg01966878 chr4:90757139 SNCA 0.3 4.82 0.4 4.11e-6 Neuroticism; TGCT cis rs2840044 1.000 rs225304 chr17:33921857 G/T cg05299278 chr17:33885742 SLFN14 0.23 5.05 0.41 1.53e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs7926906 0.715 rs7111916 chr11:90525776 C/T cg26138821 chr11:89956704 CHORDC1 -0.48 -4.91 -0.4 2.76e-6 Intelligence (multi-trait analysis); TGCT cis rs1011108 0.561 rs1053807 chr2:26800422 G/A cg18742855 chr2:26800399 C2orf70 0.29 6.48 0.5 1.99e-9 Periodontal microbiota; TGCT cis rs60843830 1.000 rs62114497 chr2:214837 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.63 5.44 0.44 2.67e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs6138458 1.000 rs227616 chr20:24908811 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs7975161 0.882 rs4406890 chr12:104638773 A/C cg25273343 chr12:104657179 TXNRD1 -0.31 -4.82 -0.4 4.08e-6 Toenail selenium levels; TGCT cis rs2486288 0.656 rs11854325 chr15:45548959 T/C cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs57221529 0.766 rs4081847 chr5:574072 C/T cg20362242 chr5:692897 TPPP 0.5 4.71 0.39 6.66e-6 Lung disease severity in cystic fibrosis; TGCT trans rs2727020 0.658 rs7111215 chr11:49430552 T/C cg03929089 chr4:120376271 NA -0.74 -8.58 -0.61 3.35e-14 Coronary artery disease; TGCT cis rs6951245 0.935 rs79067319 chr7:1065548 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.56 -0.38 1.19e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.962 rs2865985 chr4:99068009 T/C cg17366294 chr4:99064904 C4orf37 0.73 6.51 0.5 1.72e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.964 rs854813 chr17:18003845 C/T cg04398451 chr17:18023971 MYO15A 0.3 4.79 0.39 4.75e-6 Total body bone mineral density; TGCT cis rs9905704 0.624 rs4932691 chr17:57094617 T/C cg05425664 chr17:57184151 TRIM37 0.68 5.7 0.46 8.23e-8 Testicular germ cell tumor; TGCT cis rs7926906 0.575 rs1981422 chr11:90517256 G/C cg26138821 chr11:89956704 CHORDC1 -0.48 -4.96 -0.41 2.22e-6 Intelligence (multi-trait analysis); TGCT cis rs8020441 0.541 rs67026579 chr14:51155207 A/G cg04730355 chr14:51134070 SAV1 1.23 9.65 0.66 8.78e-17 Cognitive performance; TGCT cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs2245008 0.950 rs824400 chr16:83989936 C/G cg05451527 chr16:83999617 OSGIN1 0.25 4.51 0.38 1.47e-5 Pursuit maintenance gain; TGCT cis rs2932538 0.922 rs7522110 chr1:113072914 A/C cg22162597 chr1:113214053 CAPZA1 0.27 5.92 0.47 2.95e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2243480 1.000 rs160643 chr7:65558222 C/T cg18252515 chr7:66147081 NA -1.09 -7.55 -0.56 8.39e-12 Diabetic kidney disease; TGCT cis rs7552404 1.000 rs942270 chr1:76177332 G/A cg10523679 chr1:76189770 ACADM 0.9 9.75 0.66 5.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11785400 1.000 rs3824208 chr8:143743653 C/G cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs7267979 1.000 rs11087521 chr20:25440648 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9527 0.590 rs7088200 chr10:104793235 G/A cg15744005 chr10:104629667 AS3MT -0.41 -4.8 -0.4 4.43e-6 Arsenic metabolism; TGCT cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs13256369 0.826 rs7846050 chr8:8575669 A/G cg17143192 chr8:8559678 CLDN23 0.63 6.01 0.47 1.96e-8 Obesity-related traits; TGCT cis rs2180341 0.855 rs9385422 chr6:127716457 C/T cg24812749 chr6:127587940 RNF146 0.79 6.49 0.5 1.9e-9 Breast cancer; TGCT cis rs12042938 0.902 rs1094658 chr1:231773397 G/C cg04892437 chr1:231737901 TSNAX-DISC1 0.45 4.69 0.39 7.15e-6 Neuranatomic and neurocognitive phenotypes; TGCT trans rs208520 0.690 rs9345764 chr6:66820597 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.01 -10.78 -0.7 1.6e-19 Exhaled nitric oxide output; TGCT cis rs1153858 1.000 rs2467858 chr15:45711492 A/G cg26924012 chr15:45694286 SPATA5L1 0.99 12.38 0.74 2.11e-23 Homoarginine levels; TGCT cis rs7178424 0.616 rs10851703 chr15:62137215 A/G cg00456672 chr15:62358751 C2CD4A -0.31 -4.71 -0.39 6.66e-6 Height; TGCT cis rs1538970 0.816 rs868351 chr1:46009818 G/T cg05343316 chr1:45956843 TESK2 0.66 5.42 0.44 2.98e-7 Platelet count; TGCT cis rs67385638 0.802 rs11036635 chr11:5308896 C/T cg12559170 chr11:5275217 HBG2 0.41 7.74 0.57 3.03e-12 Hemoglobin levels; TGCT cis rs1048238 0.846 rs945422 chr1:16345619 T/C cg21385522 chr1:16154831 NA 0.42 4.46 0.37 1.81e-5 Systolic blood pressure; TGCT cis rs7829975 0.628 rs1109618 chr8:8571364 A/T cg17143192 chr8:8559678 CLDN23 -0.49 -4.86 -0.4 3.49e-6 Mood instability; TGCT cis rs6845621 0.727 rs7676193 chr4:18889088 C/T cg12196642 chr4:18937545 NA -0.25 -4.54 -0.38 1.3e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs11696501 0.738 rs6104294 chr20:44326850 T/C cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs3087591 1.000 rs2952980 chr17:29473353 G/A cg24425628 chr17:29625626 OMG;NF1 0.46 7.23 0.54 4.3e-11 Hip circumference; TGCT cis rs514406 0.644 rs928451 chr1:53195800 A/G cg08859206 chr1:53392774 SCP2 0.34 4.82 0.4 4.1e-6 Monocyte count; TGCT cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.82e-10 Electroencephalogram traits; TGCT cis rs9467711 1.000 rs9467707 chr6:26327905 G/C cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2486012 1.000 rs2485995 chr1:44369600 G/A cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs2692947 0.537 rs11679899 chr2:96378162 A/G cg23100626 chr2:96804247 ASTL 0.39 4.55 0.38 1.26e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs1008375 1.000 rs11737138 chr4:17657986 G/A cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11190604 1.000 rs10883507 chr10:102291275 C/T cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs910316 0.737 rs175045 chr14:75475275 A/C cg08847533 chr14:75593920 NEK9 -0.82 -7.97 -0.58 8.73e-13 Height; TGCT cis rs11098499 0.542 rs7677836 chr4:120310638 T/A cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs3733585 0.673 rs116046986 chr4:9957794 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.58e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11696501 0.688 rs6104291 chr20:44323368 C/G cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs4478858 0.684 rs2062951 chr1:31762981 T/C cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs12477438 0.501 rs11683107 chr2:99759235 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.24 0.55 4.04e-11 Chronic sinus infection; TGCT cis rs763014 1.000 rs7205409 chr16:642610 A/G cg09263875 chr16:632152 PIGQ 0.32 6.9 0.53 2.34e-10 Height; TGCT cis rs4730250 0.707 rs6960148 chr7:106786142 A/G cg02696742 chr7:106810147 HBP1 0.74 6.15 0.48 9.79e-9 Osteoarthritis; TGCT cis rs9549367 0.673 rs3024735 chr13:113819513 G/A cg18105134 chr13:113819100 PROZ -0.47 -8.12 -0.59 3.97e-13 Platelet distribution width; TGCT cis rs7772486 0.875 rs9399573 chr6:146403255 A/T cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs12142240 0.698 rs7515598 chr1:46818479 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs651907 0.557 rs17347644 chr3:101547733 C/T cg12386194 chr3:101231763 SENP7 0.46 4.59 0.38 1.06e-5 Colorectal cancer; TGCT cis rs10028773 0.568 rs6838457 chr4:120267367 A/G cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.08e-7 Educational attainment; TGCT cis rs3749237 0.576 rs3877784 chr3:49539417 C/T cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs514406 0.679 rs11206006 chr1:53218380 A/G cg25767906 chr1:53392781 SCP2 0.59 6.95 0.53 1.87e-10 Monocyte count; TGCT cis rs9296092 0.538 rs9461881 chr6:33520041 C/T cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7103648 0.966 rs10838702 chr11:47410888 G/T cg20307385 chr11:47447363 PSMC3 0.98 11.33 0.71 7.39e-21 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs6490294 0.659 rs7133964 chr12:112198021 C/G cg10833066 chr12:111807467 FAM109A 0.31 4.85 0.4 3.56e-6 Mean platelet volume; TGCT cis rs9807989 0.507 rs4479442 chr2:103054074 A/T cg03938978 chr2:103052716 IL18RAP 0.28 5.52 0.44 1.86e-7 Asthma; TGCT cis rs9399135 0.660 rs9376072 chr6:135280519 G/C cg24558204 chr6:135376177 HBS1L 0.48 5.02 0.41 1.74e-6 Red blood cell count; TGCT cis rs2456568 0.803 rs10831138 chr11:93640468 T/C cg14065697 chr11:93583672 C11orf90 -0.36 -4.45 -0.37 1.85e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836950 0.565 rs2836942 chr21:40591381 A/G cg06238570 chr21:40685208 BRWD1 -0.6 -6.3 -0.49 4.8e-9 Menarche (age at onset); TGCT cis rs12681288 0.676 rs17668031 chr8:1007176 A/G cg04851639 chr8:1020857 NA -0.32 -5.22 -0.42 7.23e-7 Schizophrenia; TGCT cis rs7666738 0.924 rs13124368 chr4:99039615 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7542091 0.704 rs4133950 chr1:210044393 C/G cg22029157 chr1:209979665 IRF6 0.64 6.1 0.48 1.23e-8 Monobrow; TGCT cis rs2172802 0.629 rs1948616 chr4:62487688 A/G cg04118610 chr4:62707027 LPHN3 -0.47 -4.96 -0.41 2.27e-6 Partial epilepsies; TGCT cis rs4237845 0.586 rs4760174 chr12:58320436 G/A cg02175503 chr12:58329896 NA 0.67 7.26 0.55 3.64e-11 Intelligence (multi-trait analysis); TGCT cis rs682748 0.810 rs6888760 chr5:17112174 C/T cg23987134 chr5:17158319 LOC285696 -0.21 -4.96 -0.41 2.31e-6 Hippocampal atrophy; TGCT cis rs1218582 0.596 rs4845676 chr1:154827861 C/G cg16680214 chr1:154839983 KCNN3 -0.25 -4.8 -0.4 4.55e-6 Prostate cancer; TGCT cis rs447921 0.813 rs34234366 chr17:74398510 C/A cg09812376 chr17:74270190 QRICH2 -0.46 -4.6 -0.38 1.01e-5 Mitochondrial DNA levels; TGCT cis rs76025697 1 rs76025697 chr5:179184488 G/A cg14593053 chr5:179126677 CANX 0.48 5.25 0.43 6.37e-7 Granulocyte percentage of myeloid white cells;Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Granulocyte count; TGCT trans rs916888 0.610 rs199452 chr17:44801340 C/T cg22968622 chr17:43663579 NA 1.0 9.72 0.66 6.16e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8017423 0.967 rs61989980 chr14:90727635 C/T cg04374321 chr14:90722782 PSMC1 0.76 7.63 0.57 5.3e-12 Mortality in heart failure; TGCT cis rs2658782 0.654 rs2248531 chr11:93255363 G/T cg15737290 chr11:93063684 CCDC67 0.64 4.93 0.4 2.59e-6 Pulmonary function decline; TGCT cis rs17601876 0.814 rs7181429 chr15:51559496 G/A cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2204008 0.606 rs1581358 chr12:38391582 G/T cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.76e-6 Bladder cancer; TGCT cis rs6866344 0.697 rs11742808 chr5:178131658 G/A cg10224037 chr5:178157518 ZNF354A 0.95 8.47 0.61 6.06e-14 Neutrophil percentage of white cells; TGCT cis rs9300255 0.602 rs1727294 chr12:123616514 A/G cg00376283 chr12:123451042 ABCB9 0.71 5.58 0.45 1.42e-7 Neutrophil percentage of white cells; TGCT cis rs35146811 0.660 rs3779045 chr7:99779259 T/C cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs2013441 0.965 rs2386485 chr17:20095246 G/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs864745 1.000 rs849142 chr7:28185891 T/C cg23620719 chr7:28220237 JAZF1 -0.5 -4.55 -0.38 1.24e-5 Crohn's disease;Type 2 diabetes; TGCT cis rs3617 0.573 rs12492391 chr3:52912296 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.52 5.05 0.41 1.55e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7617773 0.963 rs6766754 chr3:48182589 T/C cg11946769 chr3:48343235 NME6 -0.59 -5.35 -0.43 4.07e-7 Coronary artery disease; TGCT cis rs7666738 0.791 rs4699329 chr4:99056212 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs79387448 0.592 rs6728945 chr2:102986471 T/C cg09003973 chr2:102972529 NA 1.39 11.41 0.72 4.54e-21 Gut microbiota (bacterial taxa); TGCT cis rs7208859 0.623 rs73271842 chr17:29137155 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs921968 0.608 rs658378 chr2:219483881 T/A cg02176678 chr2:219576539 TTLL4 0.38 5.5 0.44 2.07e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg08280861 chr8:58055591 NA 0.52 5.94 0.47 2.65e-8 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg24675658 chr1:53192096 ZYG11B -0.69 -8.17 -0.59 3.05e-13 Monocyte count; TGCT cis rs7267979 1.000 rs2856 chr20:25433536 T/C cg14121845 chr20:25566513 NINL 0.49 5.23 0.42 7.08e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs79149102 0.579 rs7182286 chr15:75293839 A/G cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg03407747 chr17:6899364 ALOX12 -0.51 -5.48 -0.44 2.29e-7 Tonsillectomy; TGCT cis rs9549260 0.755 rs2721045 chr13:41162632 T/A cg21288729 chr13:41239152 FOXO1 1.0 10.25 0.68 3.06e-18 Red blood cell count; TGCT cis rs9818758 0.607 rs12185979 chr3:49651970 C/G cg00383909 chr3:49044727 WDR6 1.47 5.86 0.47 3.83e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs3849570 0.643 rs1851928 chr3:81975395 C/T cg07356753 chr3:81810745 GBE1 -0.64 -5.63 -0.45 1.16e-7 Waist circumference;Body mass index; TGCT cis rs2742417 0.603 rs9826208 chr3:45773991 C/T cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7772486 0.790 rs3923579 chr6:146230232 C/G cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9952991 0.882 rs2847274 chr18:12777603 T/C cg09945482 chr18:12777974 NA 0.51 4.86 0.4 3.47e-6 Inflammatory skin disease; TGCT cis rs2836950 0.565 rs7279497 chr21:40531306 A/G cg11644478 chr21:40555479 PSMG1 0.53 5.04 0.41 1.63e-6 Menarche (age at onset); TGCT cis rs2836950 0.520 rs8133928 chr21:40689963 G/A cg11890956 chr21:40555474 PSMG1 -0.65 -5.97 -0.47 2.27e-8 Menarche (age at onset); TGCT cis rs7824557 0.564 rs11781637 chr8:11214972 C/T cg21775007 chr8:11205619 TDH -0.67 -6.7 -0.52 6.64e-10 Retinal vascular caliber; TGCT cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg18402987 chr7:1209562 NA 0.72 5.97 0.47 2.31e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7267979 1.000 rs2387884 chr20:25379069 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs45509595 0.659 rs390764 chr6:27782535 C/T cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.24e-6 Breast cancer; TGCT cis rs9383153 1.000 rs7749925 chr6:16340776 C/G cg14009473 chr6:15502099 JARID2 -0.67 -5.63 -0.45 1.13e-7 Gambling; TGCT cis rs6121246 0.529 rs750144 chr20:30179027 C/T cg21427119 chr20:30132790 HM13 0.43 6.28 0.49 5.3e-9 Mean corpuscular hemoglobin; TGCT cis rs9913156 0.793 rs4346260 chr17:4567215 A/G cg23387401 chr17:4582204 PELP1 -0.31 -4.63 -0.38 8.97e-6 Lymphocyte counts; TGCT cis rs9788682 1.000 rs7164594 chr15:78803057 C/T cg24631222 chr15:78858424 CHRNA5 0.88 7.63 0.57 5.35e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3862260 0.509 rs3862262 chr1:120161841 G/T cg16322792 chr1:120165303 ZNF697 0.35 8.4 0.6 8.93e-14 Systemic lupus erythematosus; TGCT cis rs7582180 0.614 rs2241809 chr2:101014363 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.74 0.39 5.68e-6 Intelligence (multi-trait analysis); TGCT cis rs2832191 0.716 rs2249028 chr21:30365322 G/A cg24692254 chr21:30365293 RNF160 0.96 11.23 0.71 1.29e-20 Dental caries; TGCT cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg09904177 chr6:26538194 HMGN4 0.68 6.31 0.49 4.52e-9 Intelligence (multi-trait analysis); TGCT cis rs4654899 0.664 rs10799665 chr1:21152640 C/T cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.92e-10 Superior frontal gyrus grey matter volume; TGCT cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs35160687 1.000 rs35160687 chr2:86472114 C/T cg04877910 chr2:85804641 VAMP8 0.35 4.6 0.38 1.04e-5 Night sleep phenotypes; TGCT cis rs78487399 0.908 rs12463527 chr2:43815945 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs76473307 0.661 rs61558260 chr20:57414867 C/G cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg17054783 chr10:134559939 INPP5A -0.25 -4.8 -0.4 4.56e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4285028 0.898 rs12491991 chr3:121706021 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.77 6.5 0.5 1.78e-9 Multiple sclerosis; TGCT cis rs4700695 0.614 rs437399 chr5:65208533 A/G cg21114390 chr5:65439923 SFRS12 0.67 5.02 0.41 1.73e-6 Facial morphology (factor 19); TGCT cis rs7772486 0.846 rs9376976 chr6:146355605 T/C cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs4820539 1.000 rs2267003 chr22:23457098 A/G cg21100191 chr22:23484243 RTDR1 0.95 11.36 0.71 6.23e-21 Bone mineral density; TGCT cis rs79057730 0.599 rs6944167 chr7:826274 G/C cg11064039 chr7:766100 PRKAR1B;HEATR2 0.73 5.56 0.45 1.6e-7 Initial pursuit acceleration; TGCT cis rs3617 0.625 rs2239548 chr3:52854186 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.59 0.38 1.08e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6964587 0.626 rs12704631 chr7:91523525 T/C cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs2455799 0.634 rs1345160 chr3:15862026 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.82 -0.4 4.06e-6 Mean platelet volume; TGCT cis rs2439831 0.867 rs11856184 chr15:43919162 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.61 0.51 1.03e-9 Lung cancer in ever smokers; TGCT cis rs9322193 0.923 rs3798761 chr6:150004779 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs1371867 0.846 rs1788205 chr8:101306546 G/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs1008375 0.900 rs3822235 chr4:17694916 C/T cg18681998 chr4:17616180 MED28 -0.72 -6.59 -0.51 1.11e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7043114 0.525 rs1133908 chr9:95068046 C/T cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.95e-5 Height; TGCT cis rs2278034 0.502 rs3747672 chr3:195612034 T/C cg16000393 chr3:195602323 TNK2 -0.16 -4.46 -0.37 1.8e-5 Bronchopulmonary dysplasia; TGCT cis rs2439831 0.702 rs495175 chr15:43798684 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.82 5.69 0.45 8.68e-8 Lung cancer in ever smokers; TGCT cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg20637647 chr7:64974828 NA -0.94 -5.27 -0.43 5.9e-7 Diabetic kidney disease; TGCT cis rs7917772 0.503 rs7087665 chr10:104282418 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1163251 0.902 rs487081 chr1:120217389 G/A cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs9634489 0.502 rs7320228 chr13:97085948 A/G cg11411106 chr13:97107445 HS6ST3 -0.28 -5.13 -0.42 1.09e-6 Body mass index; TGCT cis rs1215050 0.740 rs1648568 chr4:98957619 A/G cg05340658 chr4:99064831 C4orf37 -0.44 -5.35 -0.43 4.13e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3749237 1.000 rs1317140 chr3:49878652 G/A cg03060546 chr3:49711283 APEH 0.7 7.05 0.54 1.08e-10 Resting heart rate; TGCT cis rs804292 0.695 rs804279 chr8:11623889 A/T cg26752888 chr8:11627280 NEIL2 0.85 8.95 0.63 4.42e-15 Alcohol dependence;Nicotine use; TGCT cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs2302045 1.000 rs2302051 chr2:242062410 C/A cg04553960 chr2:241721320 KIF1A -0.69 -4.74 -0.39 5.8e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT trans rs62103177 0.714 rs7227962 chr18:77603283 T/G cg05926928 chr17:57297772 GDPD1 1.05 10.15 0.67 5.52e-18 Opioid sensitivity; TGCT cis rs7666738 0.716 rs1426660 chr4:98876792 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg16590910 chr6:42928470 GNMT -0.49 -4.58 -0.38 1.11e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg11965913 chr1:205819406 PM20D1 0.49 6.53 0.51 1.49e-9 Menarche (age at onset); TGCT cis rs79349575 0.783 rs4793991 chr17:47001801 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs8177253 1.000 rs3811647 chr3:133484029 G/A cg08048268 chr3:133502702 NA -0.65 -9.82 -0.66 3.44e-17 Iron status biomarkers; TGCT cis rs7666738 0.830 rs10010223 chr4:99021758 G/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2180341 0.711 rs4371861 chr6:127568447 G/T cg27446573 chr6:127587934 RNF146 0.7 6.97 0.53 1.66e-10 Breast cancer; TGCT cis rs58722170 0.610 rs61776206 chr1:38073048 C/T cg17933807 chr1:38061675 GNL2 -0.83 -7.42 -0.55 1.6e-11 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6988636 1.000 rs13260626 chr8:124190317 C/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9942416 0.617 rs72633979 chr5:74990178 A/T cg19683494 chr5:74908142 NA 0.61 6.4 0.5 2.94e-9 Age-related disease endophenotypes; TGCT cis rs3812831 0.695 rs6560936 chr13:114945972 C/T cg15513719 chr13:114904418 NA -0.36 -4.46 -0.37 1.78e-5 Schizophrenia; TGCT cis rs72634258 0.554 rs12723500 chr1:7857374 G/C cg26816564 chr1:7831052 VAMP3 0.88 6.53 0.51 1.52e-9 Inflammatory bowel disease; TGCT cis rs763014 0.898 rs4984897 chr16:632180 G/C cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs763121 0.853 rs5750669 chr22:39080638 T/A cg06022373 chr22:39101656 GTPBP1 0.74 7.29 0.55 3.22e-11 Menopause (age at onset); TGCT cis rs41464348 0.515 rs870858 chr2:33501320 G/C cg16572410 chr2:33467199 LTBP1 -0.27 -4.49 -0.37 1.64e-5 Height; TGCT cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg26531700 chr6:26746687 NA 0.64 6.56 0.51 1.34e-9 Intelligence (multi-trait analysis); TGCT cis rs4506170 1.000 rs34585331 chr8:128323731 T/G cg07795030 chr8:128802207 NA -0.21 -4.66 -0.39 7.91e-6 Prostate cancer; TGCT cis rs12477438 0.520 rs2632276 chr2:99779655 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.51 0.61 4.87e-14 Chronic sinus infection; TGCT cis rs1971762 0.527 rs7311902 chr12:54015236 A/G cg16917193 chr12:54089295 NA 1.05 10.86 0.7 1e-19 Height; TGCT cis rs7666738 0.753 rs1830230 chr4:99026186 G/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1697139 0.583 rs1428475 chr5:66543954 G/T cg11553311 chr5:66541588 NA 0.28 6.02 0.48 1.82e-8 Breast cancer; TGCT cis rs7226408 0.857 rs72885287 chr18:34446659 C/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg00684032 chr4:1343700 KIAA1530 0.23 5.01 0.41 1.79e-6 Obesity-related traits; TGCT cis rs4975709 0.589 rs4975745 chr5:1861058 G/C cg07747251 chr5:1868357 NA 0.38 5.46 0.44 2.45e-7 Cardiovascular disease risk factors; TGCT cis rs12142240 0.698 rs72677594 chr1:46824371 A/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT trans rs561341 0.830 rs2301765 chr17:30202056 T/A cg20587970 chr11:113659929 NA 0.8 9.3 0.64 6.34e-16 Hip circumference adjusted for BMI; TGCT cis rs7819412 0.505 rs17782554 chr8:11022106 C/G cg21775007 chr8:11205619 TDH -0.49 -4.49 -0.37 1.59e-5 Triglycerides; TGCT cis rs9787249 0.957 rs11809515 chr1:40205326 C/A cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs9303542 0.559 rs12938390 chr17:46614722 T/C cg25032089 chr17:46643351 HOXB3 0.58 5.48 0.44 2.23e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7666738 0.830 rs1967977 chr4:98966141 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.54 0.56 8.74e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs16866061 0.962 rs3845840 chr2:225359100 G/A cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs7113874 0.569 rs10444244 chr11:8534603 T/C cg14521421 chr11:8862019 ST5 0.28 4.48 0.37 1.64e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs858239 0.867 rs10250602 chr7:23303701 T/C cg05602783 chr7:23145260 KLHL7 -0.69 -5.46 -0.44 2.51e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs13394619 1.000 rs13394619 chr2:11727507 A/G cg07314298 chr2:11723111 GREB1 0.29 5.26 0.43 6.09e-7 Endometriosis; TGCT cis rs17376456 0.741 rs10036829 chr5:93309897 G/C cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs1577917 0.958 rs7747897 chr6:86647349 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT trans rs12599106 0.679 rs34584967 chr16:34475725 T/G cg26668828 chr6:292823 DUSP22 -0.76 -8.07 -0.59 5.15e-13 Menopause (age at onset); TGCT cis rs9560113 1.000 rs9560105 chr13:112175363 A/T cg14154082 chr13:112174009 NA -0.34 -4.65 -0.39 8.49e-6 Menarche (age at onset); TGCT cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -4.96 -0.41 2.27e-6 Coronary artery disease; TGCT cis rs6684514 1.000 rs12038481 chr1:156284815 T/C cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7959452 0.590 rs6581889 chr12:69757429 T/C cg14784868 chr12:69753453 YEATS4 0.83 8.85 0.62 7.59e-15 Blood protein levels; TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs732765 1.000 rs13391 chr14:75370123 C/T cg06637938 chr14:75390232 RPS6KL1 -0.65 -5.51 -0.44 1.99e-7 Non-small cell lung cancer; TGCT cis rs1799949 0.683 rs55737636 chr17:41264739 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.44 4.67 0.39 7.7e-6 Menopause (age at onset); TGCT cis rs2980439 0.517 rs17594093 chr8:8106406 G/T cg08975724 chr8:8085496 FLJ10661 -0.55 -4.75 -0.39 5.6e-6 Neuroticism; TGCT cis rs4911259 0.507 rs8118663 chr20:31398876 A/G cg13636640 chr20:31349939 DNMT3B 0.9 7.78 0.57 2.41e-12 Inflammatory bowel disease; TGCT cis rs7095607 0.967 rs10998018 chr10:69962954 G/A cg18986048 chr10:69913749 MYPN 0.45 4.89 0.4 3.07e-6 Lung function (FVC); TGCT cis rs35771425 0.536 rs6656860 chr1:211620805 A/G cg25617285 chr1:211431773 RCOR3 -0.5 -6.15 -0.48 9.9e-9 Educational attainment (years of education); TGCT cis rs10504229 0.636 rs10958525 chr8:58051528 C/A cg20607798 chr8:58055168 NA 0.45 4.57 0.38 1.15e-5 Developmental language disorder (linguistic errors); TGCT cis rs2115630 0.936 rs8033459 chr15:85253258 C/T cg12501888 chr15:85177176 SCAND2 -0.5 -4.83 -0.4 3.89e-6 P wave terminal force; TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg24675658 chr1:53192096 ZYG11B -0.74 -9.02 -0.63 2.95e-15 Monocyte count; TGCT cis rs600231 0.542 rs11227205 chr11:65256164 G/A cg17120908 chr11:65337727 SSSCA1 -0.6 -4.58 -0.38 1.09e-5 Bone mineral density; TGCT cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7668190 1.000 rs7668190 chr4:55096270 A/T cg17187183 chr4:55093834 PDGFRA 0.44 6.04 0.48 1.63e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs586688 0.625 rs602668 chr1:201657709 A/G cg14168733 chr1:201708718 NAV1 0.52 4.45 0.37 1.86e-5 Obesity-related traits; TGCT cis rs6074578 0.679 rs6086171 chr20:136374 G/A cg16931068 chr20:139680 DEFB127 0.29 4.94 0.41 2.48e-6 Hirschsprung disease; TGCT cis rs28595532 0.920 rs115688334 chr4:119770805 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg07317062 chr7:27170388 HOXA4 -0.45 -4.62 -0.38 9.36e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs6598955 0.614 rs1134584 chr1:26608828 G/A cg04990556 chr1:26633338 UBXN11 -0.86 -10.22 -0.68 3.7e-18 Obesity-related traits; TGCT cis rs981844 1.000 rs2579917 chr4:154652648 T/G cg14289246 chr4:154710475 SFRP2 1.01 8.56 0.61 3.55e-14 Response to statins (LDL cholesterol change); TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg08859206 chr1:53392774 SCP2 -0.42 -6.4 -0.5 2.95e-9 Monocyte count; TGCT cis rs4268898 0.722 rs4665253 chr2:24382546 G/A cg05570707 chr2:24270316 C2orf44 0.48 4.59 0.38 1.08e-5 Asthma; TGCT cis rs644799 1.000 rs11021319 chr11:95523123 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9913156 0.841 rs34230287 chr17:4613630 C/T cg00122941 chr17:4613640 ARRB2 0.94 8.09 0.59 4.57e-13 Lymphocyte counts; TGCT cis rs2243480 1.000 rs1723270 chr7:65469830 T/G cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs1801251 0.963 rs13021246 chr2:233623111 T/C cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs11734570 0.581 rs75356782 chr4:38600053 T/G cg18361445 chr4:38666374 KLF3;FLJ13197 0.69 5.66 0.45 9.9e-8 Inflammatory bowel disease;Crohn's disease; TGCT cis rs2115630 1.000 rs55646601 chr15:85323568 G/T cg17173187 chr15:85201210 NMB -0.39 -4.78 -0.39 4.83e-6 P wave terminal force; TGCT cis rs7224685 0.569 rs8066378 chr17:3996334 T/C cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs6674176 0.611 rs1636876 chr1:44387228 T/G cg12908607 chr1:44402522 ARTN -0.68 -4.45 -0.37 1.89e-5 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.28 0.43 5.68e-7 Prudent dietary pattern; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg11003573 chr3:44754125 ZNF502 -0.4 -4.44 -0.37 1.96e-5 Depressive symptoms; TGCT cis rs6570726 0.902 rs406979 chr6:145838983 G/T cg23711669 chr6:146136114 FBXO30 0.7 6.46 0.5 2.12e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs17376456 0.877 rs7736620 chr5:93305762 C/T cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs3784262 0.692 rs12907125 chr15:58282621 C/A cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.05 -0.48 1.56e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4665809 0.941 rs3177055 chr2:26359315 G/A cg04944784 chr2:26401820 FAM59B -0.71 -6.27 -0.49 5.4e-9 Gut microbiome composition (summer); TGCT cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2760061 0.583 rs708113 chr1:228192753 T/A cg02753203 chr1:228287806 NA 0.33 6.31 0.49 4.41e-9 Diastolic blood pressure; TGCT cis rs62244186 0.627 rs12386385 chr3:44457540 A/G cg15687855 chr3:44754131 ZNF502 -0.41 -4.91 -0.4 2.77e-6 Depressive symptoms; TGCT cis rs3617 0.625 rs3774364 chr3:52863605 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.49 4.73 0.39 5.98e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7809950 1.000 rs2712200 chr7:107142435 G/T cg23024343 chr7:107201750 COG5 -0.35 -5.3 -0.43 5.09e-7 Coronary artery disease; TGCT cis rs10540 1.000 rs67912009 chr11:495057 G/T cg03352830 chr11:487213 PTDSS2 0.26 4.51 0.38 1.48e-5 Body mass index; TGCT cis rs1215050 0.755 rs6851840 chr4:98776366 A/G cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7926906 1.000 rs12291122 chr11:90531578 A/C cg26138821 chr11:89956704 CHORDC1 -0.53 -5.6 -0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs4689388 0.890 rs13130845 chr4:6297646 A/C cg00701064 chr4:6280414 WFS1 0.38 4.78 0.39 4.96e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs477895 0.838 rs2070765 chr11:64010085 A/G cg23719950 chr11:63933701 MACROD1 -0.65 -5.36 -0.43 3.92e-7 Mean platelet volume; TGCT cis rs4148883 0.737 rs13148577 chr4:100060836 G/A cg12011299 chr4:100065546 ADH4 0.39 6.02 0.48 1.83e-8 Alcohol dependence; TGCT cis rs28595532 0.920 rs114547492 chr4:119773078 G/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs7178572 0.568 rs12913233 chr15:77543297 C/T cg15453836 chr15:77711506 NA -0.41 -4.58 -0.38 1.13e-5 Type 2 diabetes; TGCT cis rs909674 0.524 rs5757670 chr22:39829736 G/A cg02038168 chr22:39784481 NA -0.78 -6.68 -0.51 7.08e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg12386194 chr3:101231763 SENP7 0.61 5.66 0.45 9.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7681440 0.874 rs1372523 chr4:90775923 G/A cg14346243 chr4:90757452 SNCA -0.56 -5.47 -0.44 2.41e-7 Dementia with Lewy bodies; TGCT cis rs4660261 0.526 rs2906458 chr1:44336389 A/G cg12908607 chr1:44402522 ARTN 0.66 8.26 0.6 1.85e-13 Intelligence (multi-trait analysis); TGCT cis rs9309473 0.615 rs62149774 chr2:73787652 G/A cg07208825 chr2:73871855 ALMS1P 0.24 4.68 0.39 7.32e-6 Metabolite levels; TGCT cis rs13191362 0.935 rs13212137 chr6:163010261 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2468186 0.583 rs1485293 chr8:120091999 C/T cg02248809 chr8:120845432 TAF2 -0.44 -4.71 -0.39 6.49e-6 Osteoprotegerin levels; TGCT cis rs1153858 1.000 rs12441971 chr15:45671957 A/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs6951245 0.938 rs11764937 chr7:1092074 C/T cg18402987 chr7:1209562 NA 0.61 5.03 0.41 1.66e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1552244 0.608 rs3732962 chr3:10048951 T/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg08219700 chr8:58056026 NA 0.41 4.98 0.41 2.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs1372520 0.684 rs2619347 chr4:90745770 G/A cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg16497277 chr3:49208875 KLHDC8B -0.54 -5.17 -0.42 9.07e-7 Menarche (age at onset); TGCT cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.69 0.62 1.83e-14 Platelet count; TGCT cis rs9311474 0.713 rs352169 chr3:52236762 C/T cg07507251 chr3:52567010 NT5DC2 0.39 5.21 0.42 7.71e-7 Electroencephalogram traits; TGCT cis rs4654899 0.865 rs10493006 chr1:21375904 G/A cg01072550 chr1:21505969 NA -0.47 -7.03 -0.53 1.22e-10 Superior frontal gyrus grey matter volume; TGCT trans rs12191082 0.646 rs17470494 chr6:46883834 C/T cg15621338 chr7:128577916 IRF5 1.26 6.89 0.53 2.44e-10 Mean platelet volume; TGCT cis rs17767294 0.572 rs11965137 chr6:27624749 G/A cg08851530 chr6:28072375 NA 1.23 5.63 0.45 1.14e-7 Parkinson's disease; TGCT cis rs2153535 0.580 rs1414345 chr6:8471537 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs829418 0.582 rs747662 chr1:21947218 C/G cg09118749 chr1:21952566 RAP1GAP 0.4 5.02 0.41 1.72e-6 Neurocognitive impairment in HIV-1 infection (continuous); TGCT trans rs208520 0.690 rs74707865 chr6:66717352 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs7772486 0.720 rs9403757 chr6:146261271 C/T cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1080500 1.000 rs1080500 chr3:53175017 C/T cg10802521 chr3:52805072 NEK4 -0.46 -4.51 -0.38 1.48e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs765787 0.530 rs28815867 chr15:45526805 G/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.75e-7 Uric acid levels; TGCT cis rs9611565 0.649 rs5758466 chr22:42176059 G/A cg13695892 chr22:41940480 POLR3H 0.8 7.65 0.57 4.87e-12 Vitiligo; TGCT cis rs4689388 0.890 rs4689397 chr4:6299387 G/A cg14416269 chr4:6271139 WFS1 0.4 5.33 0.43 4.42e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9906944 0.678 rs56015440 chr17:47136631 C/G cg07075026 chr17:47091521 IGF2BP1 -0.44 -4.62 -0.38 9.52e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg27286337 chr10:134555280 INPP5A 0.44 5.23 0.42 7.1e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6424115 0.830 rs6672157 chr1:24198840 C/G cg15997130 chr1:24165203 NA 0.85 9.26 0.64 7.92e-16 Immature fraction of reticulocytes; TGCT cis rs1218582 0.741 rs705094 chr1:154917314 G/A cg03351412 chr1:154909251 PMVK 0.5 4.66 0.39 7.92e-6 Prostate cancer; TGCT cis rs6570726 0.791 rs385729 chr6:145855465 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9325144 0.600 rs6582634 chr12:38748041 G/A cg13010199 chr12:38710504 ALG10B 0.52 4.53 0.38 1.37e-5 Morning vs. evening chronotype; TGCT cis rs6582630 0.519 rs8186992 chr12:38325848 C/T cg26384229 chr12:38710491 ALG10B 0.79 6.98 0.53 1.61e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs68170813 0.559 rs2249043 chr7:106960515 C/T cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.43e-8 Coronary artery disease; TGCT cis rs7666738 0.830 rs17027225 chr4:99028564 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs7412746 0.634 rs72704658 chr1:150833010 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.04 0.41 1.62e-6 Melanoma; TGCT cis rs11971779 0.793 rs11772447 chr7:139033589 T/G cg07862535 chr7:139043722 LUC7L2 0.75 6.1 0.48 1.26e-8 Diisocyanate-induced asthma; TGCT cis rs36051895 0.623 rs1575283 chr9:5238588 C/T cg02405213 chr9:5042618 JAK2 -0.73 -9.55 -0.65 1.55e-16 Pediatric autoimmune diseases; TGCT cis rs7937682 0.564 rs1944114 chr11:111366460 T/C cg09085632 chr11:111637200 PPP2R1B 0.55 4.94 0.41 2.52e-6 Primary sclerosing cholangitis; TGCT cis rs28595532 0.920 rs115354352 chr4:119750358 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs4478858 0.647 rs7524117 chr1:31738416 A/G cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs6912958 0.516 rs242278 chr6:88047059 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.72 7.53 0.56 9.05e-12 Monocyte percentage of white cells; TGCT cis rs877529 0.605 rs139397 chr22:39543371 T/C cg18708252 chr22:39545030 CBX7 -0.35 -5.18 -0.42 8.84e-7 Multiple myeloma; TGCT cis rs10465746 0.780 rs4907190 chr1:84409168 T/C cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT cis rs6424115 0.692 rs573361 chr1:24053674 A/T cg15997130 chr1:24165203 NA 0.68 6.41 0.5 2.8e-9 Immature fraction of reticulocytes; TGCT cis rs34245846 0.705 rs56382016 chr1:154828683 A/C cg06418219 chr1:154948305 SHC1;CKS1B 0.76 6.04 0.48 1.7e-8 Atrial fibrillation; TGCT cis rs9811920 0.609 rs6809988 chr3:99656615 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.65 0.51 8.38e-10 Axial length; TGCT trans rs7618501 1.000 rs1049256 chr3:49763338 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs3806843 1.000 rs2337985 chr5:140157861 T/C cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs28386778 0.765 rs1974435 chr17:61994096 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.94 -12.61 -0.75 5.71e-24 Prudent dietary pattern; TGCT cis rs12971120 0.947 rs8083001 chr18:72165058 A/G cg26446133 chr18:72167187 CNDP2 -0.39 -7.57 -0.56 7.29e-12 Refractive error; TGCT cis rs1801251 1.000 rs895430 chr2:233725483 C/A cg08000102 chr2:233561755 GIGYF2 -0.64 -6.48 -0.5 1.97e-9 Coronary artery disease; TGCT cis rs9993613 1.000 rs6446849 chr4:73459446 G/A cg15102770 chr4:73434591 ADAMTS3 -0.5 -4.62 -0.38 9.39e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs2404602 0.669 rs1875885 chr15:76638081 G/A cg26408565 chr15:76604113 ETFA -0.41 -5.3 -0.43 5.1e-7 Blood metabolite levels; TGCT cis rs5750830 0.620 rs1007337 chr22:39781585 C/T cg05872129 chr22:39784769 NA -0.95 -10.16 -0.67 5.11e-18 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Vitiligo; TGCT cis rs1150668 0.830 rs2531831 chr6:28388765 C/G cg13525197 chr6:28411240 ZSCAN23 -0.51 -4.98 -0.41 2.1e-6 Pubertal anthropometrics; TGCT trans rs8073060 0.586 rs226087 chr17:34017652 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1371867 0.846 rs1788203 chr8:101303721 T/C cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs9556958 0.588 rs9556964 chr13:99159306 T/C cg15168958 chr13:99100528 FARP1 0.23 4.69 0.39 7.03e-6 Educational attainment (years of education); TGCT cis rs3749237 0.595 rs7621003 chr3:49411404 T/C cg03060546 chr3:49711283 APEH 0.77 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs7666738 0.830 rs957742 chr4:99029409 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12711979 0.765 rs6715805 chr2:3821117 T/C cg17052675 chr2:3827356 NA -0.4 -7.82 -0.57 2.02e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs10875746 0.859 rs4760622 chr12:48591960 C/A cg20731937 chr12:48336164 NA 0.63 5.05 0.41 1.51e-6 Longevity (90 years and older); TGCT cis rs11098499 0.909 rs11098530 chr4:120413154 C/T cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs2014572 0.510 rs8111661 chr19:57752326 C/G cg24459738 chr19:57751996 ZNF805 0.53 5.08 0.42 1.32e-6 Hyperactive-impulsive symptoms; TGCT cis rs10746514 0.931 rs11582890 chr1:232251218 C/T cg09506761 chr1:232265262 NA 0.53 5.31 0.43 4.79e-7 Response to statin therapy; TGCT cis rs2153535 0.580 rs6421948 chr6:8531020 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs6988636 0.892 rs58116120 chr8:124191776 T/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9303401 0.659 rs35797125 chr17:56736547 G/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs2469997 1.000 rs2470024 chr8:120363181 C/A cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs11122272 0.735 rs973252 chr1:231520802 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -7.0 -0.53 1.41e-10 Hemoglobin concentration; TGCT cis rs611744 0.647 rs1609472 chr8:109269232 T/G cg21045802 chr8:109455806 TTC35 0.71 7.25 0.55 4.03e-11 Dupuytren's disease; TGCT cis rs11687170 0.786 rs10211471 chr2:237081854 C/T cg19324714 chr2:237145437 ASB18 0.5 4.64 0.38 8.65e-6 Educational attainment;Educational attainment (years of education); TGCT cis rs58950470 0.927 rs1193851 chr11:65386206 C/G cg27068330 chr11:65405492 SIPA1 0.6 5.37 0.43 3.81e-7 Schizophrenia; TGCT trans rs208520 0.690 rs207091 chr6:66799847 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.83 -0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs7666738 0.830 rs7662389 chr4:99019892 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.42 0.55 1.6e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.861 rs1749907 chr1:53259658 C/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs7582180 0.627 rs4149523 chr2:101007039 T/C cg08017756 chr2:100939284 LONRF2 -0.31 -5.01 -0.41 1.85e-6 Intelligence (multi-trait analysis); TGCT cis rs6722750 0.716 rs2422115 chr2:64414815 A/G cg22352474 chr2:64371530 PELI1 -0.53 -4.46 -0.37 1.83e-5 Neuroticism; TGCT cis rs72781680 0.716 rs2551334 chr2:24000396 G/A cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs1062177 1.000 rs2016409 chr5:151126324 G/T cg00977110 chr5:151150581 G3BP1 -0.41 -4.62 -0.38 9.52e-6 Preschool internalizing problems; TGCT cis rs4742903 0.967 rs2417485 chr9:106867106 A/C cg21169611 chr9:106856078 SMC2 0.5 4.65 0.39 8.38e-6 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7552404 0.727 rs5745433 chr1:76333163 T/G cg22875332 chr1:76189707 ACADM 0.58 6.08 0.48 1.36e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs644799 0.544 rs1527450 chr11:95467777 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.56 5.62 0.45 1.18e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs77372450 0.551 rs60235007 chr5:157069349 G/C cg19063654 chr5:156516798 HAVCR2 -0.37 -4.43 -0.37 2.01e-5 Bipolar disorder (body mass index interaction); TGCT trans rs6762477 0.748 rs2073726 chr3:50223593 T/A cg21659725 chr3:3221576 CRBN -0.65 -7.35 -0.55 2.37e-11 Menarche (age at onset); TGCT cis rs7223966 0.883 rs2727317 chr17:61961302 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.68 5.32 0.43 4.68e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs12210905 0.920 rs72839451 chr6:27265437 G/C cg08851530 chr6:28072375 NA 1.29 5.45 0.44 2.65e-7 Hip circumference adjusted for BMI; TGCT cis rs13191362 1.000 rs55847707 chr6:163003414 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs727505 0.954 rs7789055 chr7:124677543 G/T cg23710748 chr7:124431027 NA -0.26 -4.51 -0.38 1.49e-5 Lewy body disease; TGCT cis rs79349575 0.783 rs903567 chr17:46980318 C/T cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT cis rs9517302 0.665 rs3752968 chr13:99097025 C/T cg22223119 chr13:99095684 FARP1 -0.54 -6.16 -0.48 9.37e-9 Obesity-related traits; TGCT cis rs9916302 0.904 rs8079355 chr17:37473018 G/A cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs921968 0.541 rs4674308 chr2:219310483 A/C cg02176678 chr2:219576539 TTLL4 0.47 6.72 0.52 5.75e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6964587 0.967 rs1978061 chr7:91779242 G/A cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.33e-6 Breast cancer; TGCT trans rs11088226 0.645 rs78172258 chr21:33936539 T/G cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT cis rs2455799 0.586 rs6805034 chr3:15856929 C/G cg12172478 chr3:16357591 RFTN1 -0.31 -4.62 -0.38 9.31e-6 Mean platelet volume; TGCT cis rs12477438 0.520 rs1044575 chr2:99812070 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT trans rs1005277 0.505 rs10827836 chr10:38215441 A/G cg17830980 chr10:43048298 ZNF37B 0.73 8.35 0.6 1.13e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.55 -5.58 -0.45 1.47e-7 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.802 rs10765639 chr11:93636194 G/A cg14065697 chr11:93583672 C11orf90 -0.37 -4.63 -0.38 9.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7666738 0.830 rs9996098 chr4:98867740 T/C cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 -0.82 -8.64 -0.61 2.39e-14 Age at first birth; TGCT cis rs4253772 0.591 rs6519993 chr22:46656479 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.55 4.46 0.37 1.84e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs3771570 1.000 rs73004382 chr2:242382192 C/T cg21155796 chr2:242212141 HDLBP 0.93 6.6 0.51 1.08e-9 Prostate cancer; TGCT cis rs4824093 0.545 rs58876234 chr22:50258868 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.48 4.97 0.41 2.17e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6701037 0.681 rs2285220 chr1:175130773 T/A cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg00814883 chr7:100076585 TSC22D4 -0.89 -9.26 -0.64 7.79e-16 Platelet count; TGCT cis rs4389656 0.740 rs274706 chr5:6726629 T/C cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs4810479 0.513 rs3746506 chr20:44586036 G/A cg23252815 chr20:44420276 WFDC3;DNTTIP1 0.31 5.35 0.43 4.06e-7 Metabolite levels; TGCT cis rs9926296 0.572 rs8046872 chr16:89841552 T/C cg03388025 chr16:89894329 SPIRE2 0.35 5.13 0.42 1.09e-6 Vitiligo; TGCT cis rs17433780 0.928 rs10922533 chr1:89456659 C/G cg09516651 chr1:89888402 LOC400759 0.32 5.89 0.47 3.35e-8 Carotid intima media thickness; TGCT cis rs875971 0.895 rs1833495 chr7:65921595 T/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs8017423 0.967 rs4904658 chr14:90721640 C/T cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs7568458 0.846 rs7605975 chr2:85772548 C/T cg02493740 chr2:85810744 VAMP5 -0.29 -5.47 -0.44 2.37e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7818688 0.697 rs11776186 chr8:95971968 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs992157 0.932 rs10203039 chr2:219187367 T/C cg00012203 chr2:219082015 ARPC2 0.69 6.96 0.53 1.78e-10 Colorectal cancer; TGCT cis rs644799 0.710 rs1852535 chr11:95501241 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.26 0.6 1.89e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10838634 1.000 rs11039015 chr11:46897865 C/T cg18332754 chr11:46939436 LRP4 -0.89 -4.77 -0.39 5.13e-6 Schizophrenia; TGCT cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg07061783 chr6:25882402 NA -0.62 -6.15 -0.48 9.71e-9 Intelligence (multi-trait analysis); TGCT cis rs769267 0.930 rs2301784 chr19:19390749 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs514406 0.763 rs6685599 chr1:53213172 G/A cg16325326 chr1:53192061 ZYG11B -0.74 -9.11 -0.63 1.79e-15 Monocyte count; TGCT cis rs1153858 1.000 rs12595087 chr15:45655232 A/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs6089584 0.606 rs6089599 chr20:60576992 A/G cg13770153 chr20:60521292 NA 0.4 4.99 0.41 2.03e-6 Body mass index; TGCT cis rs739496 0.947 rs10849948 chr12:111875410 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.51 0.44 2.01e-7 Platelet count; TGCT cis rs34734847 0.933 rs998727 chr12:121149064 T/G cg21892295 chr12:121157589 UNC119B -0.22 -5.32 -0.43 4.75e-7 Mean corpuscular volume; TGCT cis rs9457247 0.624 rs2239826 chr6:167504880 T/C cg07741184 chr6:167504864 NA 0.28 5.56 0.45 1.57e-7 Crohn's disease; TGCT cis rs28595532 0.920 rs115681185 chr4:119757700 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4704846 1.000 rs4704737 chr5:156533219 A/G cg12943317 chr5:156479607 HAVCR1 -0.34 -4.7 -0.39 6.82e-6 Blood protein levels; TGCT cis rs7655441 0.964 rs12647691 chr4:80905990 C/G cg02241357 chr4:80885279 ANTXR2 -0.24 -4.59 -0.38 1.07e-5 Neutrophil percentage of white cells; TGCT cis rs7267979 1.000 rs2424713 chr20:25418482 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.525 rs1535274 chr6:26520747 A/C cg09904177 chr6:26538194 HMGN4 0.5 4.76 0.39 5.25e-6 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.767 rs3808513 chr8:11157460 G/T cg21775007 chr8:11205619 TDH -0.52 -5.07 -0.41 1.39e-6 Retinal vascular caliber; TGCT cis rs11098499 0.909 rs28793658 chr4:120307214 A/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs9914988 0.778 rs4794837 chr17:27110024 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9814567 0.778 rs4955546 chr3:134334738 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.73 -6.66 -0.51 7.8e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9611565 0.573 rs9306355 chr22:42111896 A/T cg03806693 chr22:41940476 POLR3H 0.96 9.91 0.66 2.06e-17 Vitiligo; TGCT cis rs801193 1.000 rs13239306 chr7:66136017 T/G cg00343986 chr7:65444356 GUSB -0.22 -4.71 -0.39 6.63e-6 Aortic root size; TGCT cis rs12615966 1.000 rs9941579 chr2:105384506 C/T cg16465502 chr2:105461796 NA 0.78 5.01 0.41 1.83e-6 Pancreatic cancer; TGCT cis rs6815814 0.950 rs3924112 chr4:38795810 C/T cg02016764 chr4:38805732 TLR1 -0.34 -5.4 -0.44 3.2e-7 Breast cancer; TGCT cis rs7666738 0.830 rs10012167 chr4:99048579 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.505 rs447581 chr1:53177098 T/C cg01802117 chr1:53393560 SCP2 -0.42 -4.88 -0.4 3.24e-6 Monocyte count; TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg01802117 chr1:53393560 SCP2 0.41 4.93 0.4 2.56e-6 Monocyte count; TGCT cis rs12142240 0.698 rs17361950 chr1:46864150 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.72 0.46 7.49e-8 Menopause (age at onset); TGCT cis rs524281 0.861 rs2293121 chr11:65961347 T/G cg00563793 chr11:65837595 PACS1 0.53 4.67 0.39 7.6e-6 Electroencephalogram traits; TGCT cis rs17125944 0.505 rs10483618 chr14:53203590 T/C cg00686598 chr14:53173677 PSMC6 1.09 5.66 0.45 1e-7 Alzheimer's disease (late onset); TGCT cis rs6570726 0.846 rs7773939 chr6:145927384 C/T cg23711669 chr6:146136114 FBXO30 -0.79 -8.46 -0.6 6.26e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs10992471 0.603 rs4743873 chr9:95270781 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.61 5.55 0.45 1.62e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7677751 1.000 rs7677751 chr4:55124460 C/T cg17187183 chr4:55093834 PDGFRA 0.49 5.0 0.41 1.94e-6 Corneal astigmatism; TGCT cis rs796364 1.000 rs769950 chr2:200730028 A/G cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs11578119 0.836 rs12402306 chr1:170377418 C/T cg09767346 chr1:170501363 GORAB 0.74 5.94 0.47 2.67e-8 Male-pattern baldness; TGCT trans rs9929218 0.551 rs8051095 chr16:68722049 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.62 8.24 0.59 2.07e-13 Colorectal cancer; TGCT cis rs7772486 0.790 rs6917482 chr6:146243581 C/T cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg05785598 chr3:49045655 WDR6 0.36 4.87 0.4 3.27e-6 Menarche (age at onset); TGCT cis rs2777491 0.915 rs8036498 chr15:41603276 A/G cg18705301 chr15:41695430 NDUFAF1 -0.77 -10.8 -0.7 1.46e-19 Ulcerative colitis; TGCT cis rs2862064 1.000 rs4407618 chr5:156445875 A/C cg12943317 chr5:156479607 HAVCR1 -0.38 -5.14 -0.42 1.02e-6 Platelet count; TGCT cis rs644799 1.000 rs651445 chr11:95539122 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12908161 0.960 rs62019463 chr15:85288087 G/A cg12863693 chr15:85201151 NMB 0.42 4.99 0.41 2.03e-6 Schizophrenia; TGCT cis rs9914988 0.943 rs9908881 chr17:27100924 T/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg17054783 chr10:134559939 INPP5A 0.24 4.83 0.4 3.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1355223 0.583 rs2915179 chr11:34871943 C/T cg11058730 chr11:34937778 PDHX;APIP 0.79 8.68 0.61 1.94e-14 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs16854884 0.683 rs920968 chr3:143770698 C/G cg06585982 chr3:143692056 C3orf58 0.54 4.54 0.38 1.33e-5 Economic and political preferences (feminism/equality); TGCT cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg02018176 chr4:1364513 KIAA1530 0.29 4.81 0.4 4.22e-6 Longevity; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.11e-7 Lymphocyte counts; TGCT cis rs4654899 1.000 rs10799685 chr1:21465930 A/C cg01072550 chr1:21505969 NA 0.51 8.3 0.6 1.5e-13 Superior frontal gyrus grey matter volume; TGCT cis rs4478858 0.735 rs68008576 chr1:31805905 T/C cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs11792861 0.555 rs4978767 chr9:111762925 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.65 7.42 0.55 1.59e-11 Menarche (age at onset); TGCT cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs1843834 0.721 rs4674939 chr2:225613552 G/A cg22455342 chr2:225449267 CUL3 0.65 6.29 0.49 5.01e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs11601602 0.531 rs35031414 chr11:28545563 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.64 4.54 0.38 1.3e-5 Obesity-related traits; TGCT cis rs6964587 1.000 rs4265 chr7:91719608 A/G cg17063962 chr7:91808500 NA -0.9 -10.29 -0.68 2.43e-18 Breast cancer; TGCT cis rs3087591 0.664 rs2854308 chr17:29666539 A/G cg24425628 chr17:29625626 OMG;NF1 0.39 5.56 0.45 1.57e-7 Hip circumference; TGCT cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2762353 0.718 rs1184804 chr6:25868226 T/C cg03264133 chr6:25882463 NA -0.68 -7.58 -0.56 7e-12 Blood metabolite levels; TGCT cis rs6693567 0.565 rs1262432 chr1:150371839 C/A cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs7100689 0.646 rs7098045 chr10:82123856 G/C cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs7539409 0.915 rs1977119 chr1:84275509 A/G cg10977910 chr1:84465055 TTLL7 0.95 5.28 0.43 5.5e-7 Alzheimer's disease; TGCT cis rs933688 0.938 rs6869048 chr5:90664322 G/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.03 9.42 0.65 3.21e-16 Smoking behavior; TGCT cis rs244731 0.959 rs6556307 chr5:176641434 C/T cg16006841 chr5:176797999 RGS14 0.54 6.99 0.53 1.51e-10 Urate levels in lean individuals; TGCT trans rs561341 1.000 rs72823785 chr17:30273784 C/T cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs7809950 1.000 rs10267907 chr7:107184466 C/T cg23024343 chr7:107201750 COG5 -0.35 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs9911578 0.967 rs8075786 chr17:56819216 T/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs4665809 1.000 rs6750681 chr2:26329677 C/T cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs2235642 0.750 rs2755185 chr16:1645827 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.26 -4.55 -0.38 1.27e-5 Coronary artery disease; TGCT cis rs4664308 1.000 rs6759836 chr2:160912802 C/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs6964587 1.000 rs13231820 chr7:91663529 A/G cg17063962 chr7:91808500 NA 0.88 9.54 0.65 1.69e-16 Breast cancer; TGCT cis rs4242434 0.672 rs10099266 chr8:22484268 C/G cg03733263 chr8:22462867 KIAA1967 0.97 13.6 0.77 2.44e-26 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2836974 0.932 rs35571600 chr21:40590624 A/C cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.3e-9 Cognitive function; TGCT cis rs9381040 1.000 rs2093396 chr6:41155000 G/A cg03526776 chr6:41159608 TREML2 0.34 6.97 0.53 1.62e-10 Alzheimer's disease (late onset); TGCT cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs2361718 0.590 rs4527052 chr17:78140910 A/G cg21238619 chr17:78079768 GAA -0.31 -4.57 -0.38 1.16e-5 Yeast infection; TGCT cis rs2354432 0.607 rs7511989 chr1:146720160 A/G cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs1887596 0.624 rs2150472 chr13:27145012 G/A cg01312412 chr13:27282625 NA 0.27 4.87 0.4 3.37e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs11677370 0.574 rs12329183 chr2:3866943 G/A cg17052675 chr2:3827356 NA -0.43 -6.82 -0.52 3.48e-10 Type 2 diabetes; TGCT cis rs2658782 0.951 rs2608215 chr11:93148817 G/A cg18152523 chr11:93063302 CCDC67 -0.7 -5.73 -0.46 7.25e-8 Pulmonary function decline; TGCT cis rs9910055 0.530 rs11652651 chr17:42302907 A/G cg13607699 chr17:42295918 UBTF -0.96 -10.78 -0.7 1.58e-19 Total body bone mineral density; TGCT cis rs7973719 1.000 rs7973719 chr12:7334813 C/T cg07052231 chr12:7363540 PEX5 0.34 5.03 0.41 1.7e-6 IgG glycosylation; TGCT cis rs74233809 1.000 rs11191479 chr10:104723620 T/C cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs13118159 0.725 rs71614967 chr4:1341291 A/G cg22683308 chr4:1340831 KIAA1530 -0.64 -5.88 -0.47 3.6e-8 Longevity; TGCT cis rs2933343 1.000 rs789227 chr3:128600585 C/G cg11901034 chr3:128598214 ACAD9 -0.64 -5.05 -0.41 1.56e-6 IgG glycosylation; TGCT cis rs2153535 0.601 rs7738877 chr6:8542230 A/G cg23788917 chr6:8435910 SLC35B3 0.6 5.41 0.44 3.1e-7 Motion sickness; TGCT cis rs910316 0.789 rs175444 chr14:75601782 G/C cg11812906 chr14:75593930 NEK9 -0.63 -5.81 -0.46 4.98e-8 Height; TGCT cis rs992157 0.585 rs62182795 chr2:219100202 C/T cg00012203 chr2:219082015 ARPC2 -0.81 -9.41 -0.65 3.47e-16 Colorectal cancer; TGCT cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg10802521 chr3:52805072 NEK4 -0.72 -8.85 -0.62 7.34e-15 Bipolar disorder; TGCT cis rs4713118 0.512 rs2622319 chr6:28120401 G/C cg10876282 chr6:28092338 ZSCAN16 0.49 4.53 0.38 1.37e-5 Parkinson's disease; TGCT cis rs13108904 0.818 rs3775099 chr4:1232510 C/G cg13395646 chr4:1353034 KIAA1530 -0.35 -4.51 -0.38 1.51e-5 Obesity-related traits; TGCT cis rs1153858 1.000 rs1618874 chr15:45622786 A/G cg26924012 chr15:45694286 SPATA5L1 0.96 11.77 0.73 6.36e-22 Homoarginine levels; TGCT cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg04025307 chr7:1156635 C7orf50 0.23 5.23 0.43 6.91e-7 Longevity;Endometriosis; TGCT cis rs6977660 0.652 rs58559474 chr7:19751569 C/T cg07541023 chr7:19748670 TWISTNB 1.15 7.28 0.55 3.33e-11 Thyroid stimulating hormone; TGCT cis rs4665809 1.000 rs1371553 chr2:26262948 G/A cg04944784 chr2:26401820 FAM59B -0.68 -6.07 -0.48 1.45e-8 Gut microbiome composition (summer); TGCT cis rs854765 0.583 rs4925130 chr17:17807858 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.58 0.56 7.18e-12 Total body bone mineral density; TGCT cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg22168489 chr12:122356033 WDR66 0.19 4.57 0.38 1.18e-5 Mean corpuscular volume; TGCT cis rs4808199 0.948 rs7259434 chr19:19428805 A/T cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.48 0.44 2.24e-7 Nonalcoholic fatty liver disease; TGCT cis rs7226408 0.901 rs56360477 chr18:34456833 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs700585 0.769 rs244760 chr5:88111209 C/G cg02265379 chr5:87898506 LOC645323 0.4 4.91 0.4 2.8e-6 Platelet count; TGCT trans rs797680 0.856 rs637646 chr1:93716383 A/C cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs12497850 0.897 rs9884022 chr3:48956862 G/C cg07636037 chr3:49044803 WDR6 0.94 10.29 0.68 2.43e-18 Parkinson's disease; TGCT cis rs17401966 0.838 rs946502 chr1:10309279 G/C cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs11247915 0.622 rs34370465 chr1:26670609 C/T cg23732845 chr1:26663426 AIM1L -0.37 -4.63 -0.38 8.98e-6 Obesity-related traits; TGCT cis rs7818688 0.697 rs80217195 chr8:95986853 T/C cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs9467773 1.000 rs10484442 chr6:26555879 A/G cg05738196 chr6:26577821 NA 0.91 12.79 0.75 2.07e-24 Intelligence (multi-trait analysis); TGCT cis rs4727027 0.901 rs6944781 chr7:148829566 A/G cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12579753 0.871 rs1922540 chr12:82197496 A/G cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs60733400 0.818 rs10909839 chr1:2708430 G/A cg18854424 chr1:2615690 NA 0.45 4.99 0.41 1.99e-6 Multiple sclerosis; TGCT cis rs9611565 0.729 rs12165508 chr22:41819960 T/C cg03806693 chr22:41940476 POLR3H 1.03 11.32 0.71 7.58e-21 Vitiligo; TGCT cis rs67478160 0.575 rs8014294 chr14:104322983 A/G cg26031613 chr14:104095156 KLC1 -0.65 -6.52 -0.51 1.63e-9 Schizophrenia; TGCT cis rs7584330 0.744 rs58223447 chr2:238378644 G/C cg14458575 chr2:238380390 NA 0.61 9.25 0.64 8.25e-16 Prostate cancer; TGCT cis rs1005277 0.579 rs2472173 chr10:38374638 G/A cg25427524 chr10:38739819 LOC399744 -0.39 -7.88 -0.58 1.44e-12 Extrinsic epigenetic age acceleration; TGCT cis rs4722166 0.604 rs2390715 chr7:22783878 A/C cg26061582 chr7:22766209 IL6 0.57 7.31 0.55 2.85e-11 Lung cancer; TGCT cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg08219700 chr8:58056026 NA 0.3 4.55 0.38 1.27e-5 Developmental language disorder (linguistic errors); TGCT trans rs1005277 0.579 rs9299760 chr10:38377920 C/T cg17830980 chr10:43048298 ZNF37B -0.87 -11.11 -0.71 2.53e-20 Extrinsic epigenetic age acceleration; TGCT trans rs1814175 0.653 rs10839480 chr11:50034556 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs3091242 0.836 rs35346083 chr1:25788425 C/A cg23205692 chr1:25664452 TMEM50A -0.49 -5.1 -0.42 1.26e-6 Erythrocyte sedimentation rate; TGCT cis rs7432375 0.901 rs9836231 chr3:136414321 C/T cg12473912 chr3:136751656 NA -0.36 -5.06 -0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs858239 0.932 rs1637190 chr7:23269065 A/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.22 -0.42 7.35e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs7772486 0.754 rs9399567 chr6:146147295 C/T cg05347473 chr6:146136440 FBXO30 0.53 5.06 0.41 1.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3008870 0.959 rs4655658 chr1:67389608 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg08439880 chr3:133502540 NA -0.36 -7.05 -0.53 1.1e-10 Iron status biomarkers; TGCT cis rs6977955 1.000 rs2189965 chr7:28172014 C/T cg23620719 chr7:28220237 JAZF1 0.59 4.63 0.38 9.15e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2820315 1.000 rs2644122 chr1:201810407 A/G cg12730843 chr1:201915899 LMOD1 -0.27 -4.76 -0.39 5.2e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs3806843 0.966 rs2563267 chr5:140136913 C/T cg19875535 chr5:140030758 IK -0.37 -6.32 -0.49 4.29e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4601821 0.789 rs7123797 chr11:113262571 A/G cg14159747 chr11:113255604 NA 0.4 4.94 0.41 2.46e-6 Alcoholic chronic pancreatitis; TGCT cis rs6088580 0.634 rs6059897 chr20:33113224 A/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs1215050 0.874 rs2167893 chr4:99048464 A/T cg17366294 chr4:99064904 C4orf37 0.49 4.93 0.41 2.55e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3820068 0.532 rs6701009 chr1:15935614 T/C cg05660106 chr1:15850417 CASP9 0.75 7.3 0.55 3.1e-11 Systolic blood pressure; TGCT cis rs1885364 0.740 rs9608641 chr22:28093712 G/A cg17187762 chr22:28070120 NA 0.25 4.48 0.37 1.67e-5 Facial morphology (factor 8, orbital inclination due to vertical and horizontal position of exocanthion); TGCT cis rs727563 0.580 rs202626 chr22:41847190 C/A cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs35685312 chr4:98858521 G/A cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg26338869 chr17:61819248 STRADA 0.56 5.12 0.42 1.13e-6 Prudent dietary pattern; TGCT cis rs2288073 0.965 rs13395596 chr2:24410738 T/C cg05570707 chr2:24270316 C2orf44 -0.5 -4.49 -0.37 1.58e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs2469997 0.925 rs2470032 chr8:120371299 A/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg25703541 chr22:24373054 LOC391322 -0.94 -11.32 -0.71 7.74e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11673344 0.523 rs2562599 chr19:37516374 A/C cg08039142 chr19:36980659 ZNF566 -0.51 -4.8 -0.4 4.53e-6 Obesity-related traits; TGCT cis rs2180341 0.960 rs9398839 chr6:127665863 G/A cg24812749 chr6:127587940 RNF146 1.02 7.68 0.57 4.11e-12 Breast cancer; TGCT cis rs8072100 0.811 rs9889709 chr17:45445229 C/T cg08085267 chr17:45401833 C17orf57 -0.49 -5.6 -0.45 1.33e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs854765 0.506 rs7210400 chr17:17949957 C/T cg09796270 chr17:17721594 SREBF1 -0.26 -5.16 -0.42 9.37e-7 Total body bone mineral density; TGCT cis rs651907 0.535 rs11711903 chr3:101500748 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.82 9.98 0.67 1.4e-17 Colorectal cancer; TGCT cis rs7826238 0.601 rs2979206 chr8:8345581 G/C cg08975724 chr8:8085496 FLJ10661 0.61 5.93 0.47 2.78e-8 Systolic blood pressure; TGCT cis rs9926296 0.528 rs4785721 chr16:89839997 G/A cg03388025 chr16:89894329 SPIRE2 0.5 8.5 0.61 4.92e-14 Vitiligo; TGCT cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg23172400 chr8:95962367 TP53INP1 -0.4 -6.79 -0.52 4.23e-10 Type 2 diabetes; TGCT cis rs9858542 0.537 rs35869135 chr3:49359102 A/G cg00383909 chr3:49044727 WDR6 0.67 4.53 0.38 1.38e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg05754148 chr16:3507555 NAT15 -0.39 -4.59 -0.38 1.06e-5 Tuberculosis; TGCT cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg13695892 chr22:41940480 POLR3H 0.88 8.63 0.61 2.45e-14 Vitiligo; TGCT cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs4665809 chr2:26251361 C/T cg04944784 chr2:26401820 FAM59B 0.67 6.16 0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs2836974 0.583 rs9981884 chr21:40585633 G/A cg17971929 chr21:40555470 PSMG1 0.64 6.01 0.48 1.88e-8 Cognitive function; TGCT cis rs7208859 0.623 rs9916727 chr17:29107472 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11242417 0.786 rs11746476 chr5:137511540 T/C ch.5.2533205R chr5:137273929 FAM13B;PKD2L2 -0.54 -4.64 -0.38 8.86e-6 Immune reponse to smallpox (secreted IL-12p40); TGCT cis rs7959452 0.557 rs899224 chr12:69784774 A/G cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs2594989 0.943 rs2244617 chr3:11503097 T/C cg00170343 chr3:11313890 ATG7 0.69 5.12 0.42 1.16e-6 Circulating chemerin levels; TGCT cis rs394563 0.559 rs7752555 chr6:149671116 A/G cg11245181 chr6:149772854 ZC3H12D 0.28 4.5 0.37 1.57e-5 Dupuytren's disease; TGCT cis rs2075371 0.897 rs1646743 chr7:134003451 C/A cg11752832 chr7:134001865 SLC35B4 0.81 7.72 0.57 3.36e-12 Mean platelet volume; TGCT cis rs589448 0.902 rs642786 chr12:69758462 T/C cg11871910 chr12:69753446 YEATS4 0.88 10.41 0.68 1.28e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg03806693 chr22:41940476 POLR3H -1.14 -13.51 -0.77 4e-26 Vitiligo; TGCT cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg13397359 chr6:42928475 GNMT 0.73 6.51 0.5 1.65e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs3820068 0.603 rs1122387 chr1:15947282 T/C cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.26e-13 Systolic blood pressure; TGCT cis rs6750047 0.647 rs11124632 chr2:38276412 G/C cg07380506 chr2:38303506 CYP1B1 0.62 5.7 0.46 8.25e-8 Cutaneous malignant melanoma;Melanoma; TGCT cis rs155076 0.938 rs9509630 chr13:21844314 G/A cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs11030122 0.702 rs995498 chr11:3967791 A/G cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs1552244 0.882 rs2030564 chr3:10039044 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.87 5.88 0.47 3.64e-8 Alzheimer's disease; TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.74 -0.39 5.77e-6 Prudent dietary pattern; TGCT cis rs9796 0.553 rs2925343 chr15:41306493 T/C cg18705301 chr15:41695430 NDUFAF1 0.52 6.74 0.52 5.41e-10 Menopause (age at onset); TGCT cis rs7681440 0.904 rs2301135 chr4:90758389 G/C cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.87e-8 Dementia with Lewy bodies; TGCT cis rs11190604 1.000 rs2003284 chr10:102202338 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1153858 1.000 rs4775909 chr15:45643042 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.63e-8 Homoarginine levels; TGCT cis rs10883723 0.703 rs7898410 chr10:104245858 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg27535305 chr1:53392650 SCP2 0.26 5.05 0.41 1.53e-6 Monocyte count; TGCT cis rs7500321 1.000 rs7500321 chr16:28977020 G/A cg01117621 chr16:28073818 GSG1L -0.35 -4.47 -0.37 1.76e-5 Intelligence (multi-trait analysis); TGCT cis rs61990749 0.597 rs2364584 chr14:78152286 T/C cg02301378 chr14:78227641 SNW1;C14orf178 -0.62 -4.59 -0.38 1.09e-5 Fibroblast growth factor basic levels; TGCT cis rs7267979 0.932 rs2260997 chr20:25256266 A/C cg03522245 chr20:25566470 NINL -0.63 -7.09 -0.54 8.76e-11 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9914544 0.966 rs1737943 chr17:18841590 A/G cg26306683 chr17:18585705 ZNF286B -0.58 -5.2 -0.42 8.01e-7 Educational attainment (years of education); TGCT cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 4.96 0.41 2.26e-6 Colorectal cancer; TGCT cis rs9913156 0.894 rs28365158 chr17:4620928 T/C cg00122941 chr17:4613640 ARRB2 0.94 8.09 0.59 4.57e-13 Lymphocyte counts; TGCT cis rs4819052 1.000 rs2297285 chr21:46705621 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.67 -4.55 -0.38 1.28e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3096299 0.874 rs3102342 chr16:89451575 T/C cg06640241 chr16:89574553 SPG7 0.65 6.32 0.49 4.2e-9 Multiple myeloma (IgH translocation); TGCT cis rs6582630 0.502 rs8186661 chr12:38380781 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.3 0.55 2.97e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs988712 0.550 rs988748 chr11:27724745 C/G cg10635145 chr11:27742435 BDNF 0.44 6.3 0.49 4.71e-9 Obesity; TGCT cis rs7552404 1.000 rs4949674 chr1:76213715 C/A cg03433033 chr1:76189801 ACADM 0.81 9.52 0.65 1.84e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2303745 0.589 rs751599 chr19:17396549 A/G cg04248312 chr19:17393744 ANKLE1 -0.32 -5.35 -0.43 4.12e-7 Systemic lupus erythematosus; TGCT cis rs79349575 0.594 rs62078375 chr17:47034974 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.99e-5 Type 2 diabetes; TGCT cis rs4466137 1.000 rs1154888 chr5:82977410 C/A cg16102102 chr5:83017553 HAPLN1 -0.93 -10.85 -0.7 1.06e-19 Prostate cancer; TGCT trans rs1973993 0.567 rs2800433 chr1:96998126 T/A cg10631902 chr5:14652156 NA 0.37 9.49 0.65 2.22e-16 Weight; TGCT cis rs11577318 1.000 rs11577318 chr1:26601570 A/G cg04990556 chr1:26633338 UBXN11 0.66 5.01 0.41 1.85e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7542091 0.704 rs1883331 chr1:210043483 A/G cg23283495 chr1:209979779 IRF6 0.55 5.47 0.44 2.34e-7 Monobrow; TGCT cis rs6901250 0.851 rs7740481 chr6:117149307 G/C cg12892004 chr6:117198278 RFX6 0.54 6.65 0.51 8.24e-10 C-reactive protein levels; TGCT cis rs1552244 0.554 rs34883592 chr3:10046165 C/T cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs7666738 0.791 rs1830231 chr4:99026185 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs669446 0.591 rs649504 chr1:44105948 T/C cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs79057730 0.599 rs35928068 chr7:805363 G/C cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.41 0.44 3.16e-7 Initial pursuit acceleration; TGCT trans rs4332037 0.539 rs57148375 chr7:2025001 G/C cg25206134 chr2:45395956 NA 0.97 7.33 0.55 2.6e-11 Bipolar disorder; TGCT cis rs514406 0.644 rs928451 chr1:53195800 A/G cg24675658 chr1:53192096 ZYG11B 0.84 10.45 0.68 1.03e-18 Monocyte count; TGCT cis rs7267979 1.000 rs10966 chr20:25282944 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs28451001 chr4:98924544 T/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7860634 0.872 rs7847312 chr9:139089718 A/C cg04455058 chr9:139085579 NA 0.47 5.14 0.42 1.04e-6 Thyroid hormone levels; TGCT cis rs35146811 0.735 rs7811662 chr7:99792608 A/G cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs7824557 0.545 rs2572450 chr8:11229638 C/T cg21775007 chr8:11205619 TDH -0.66 -6.47 -0.5 2.01e-9 Retinal vascular caliber; TGCT cis rs763121 0.853 rs2072796 chr22:39064230 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.98e-12 Menopause (age at onset); TGCT cis rs6570726 0.935 rs414646 chr6:145831685 T/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.962 rs6122352 chr20:61668284 T/C cg02380750 chr20:61661411 NA 0.33 5.88 0.47 3.54e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1790761 0.504 rs61894496 chr11:67391907 C/T cg00864171 chr11:67383662 NA 0.33 5.06 0.41 1.47e-6 Mean corpuscular volume; TGCT cis rs9303401 0.659 rs62083368 chr17:56878062 G/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs6912958 0.935 rs6454629 chr6:88165515 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.74 -0.39 5.79e-6 Monocyte percentage of white cells; TGCT cis rs8180040 0.966 rs11719877 chr3:47425473 C/T cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs2228638 0.816 rs2269088 chr10:33530050 A/G cg08604594 chr10:33798231 NA -0.39 -4.82 -0.4 4.2e-6 Tetralogy of Fallot; TGCT cis rs9527 0.590 rs10509766 chr10:104926334 T/C cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.07e-7 Arsenic metabolism; TGCT cis rs806215 0.526 rs62481447 chr7:127563189 G/T cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.37e-6 Type 2 diabetes; TGCT cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs36051895 0.658 rs72699574 chr9:5020089 G/A cg02405213 chr9:5042618 JAK2 -0.71 -9.1 -0.63 1.89e-15 Pediatric autoimmune diseases; TGCT cis rs73198271 0.653 rs10087742 chr8:8660474 A/G cg06636001 chr8:8085503 FLJ10661 -0.6 -4.47 -0.37 1.78e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7772486 0.790 rs2253768 chr6:146199922 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.43 -0.37 2.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10193935 0.818 rs10221927 chr2:42546680 A/C cg27598129 chr2:42591480 NA -0.41 -5.59 -0.45 1.4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg16145915 chr7:1198662 ZFAND2A -0.62 -8.32 -0.6 1.37e-13 Longevity;Endometriosis; TGCT cis rs782590 0.934 rs17369191 chr2:55757885 T/C cg18811423 chr2:55921094 PNPT1 0.66 7.14 0.54 7.11e-11 Metabolic syndrome; TGCT cis rs6504950 0.720 rs7216138 chr17:52995664 G/A cg07707039 chr17:53042137 COX11 0.27 4.66 0.39 8.15e-6 Breast cancer; TGCT cis rs7819412 0.561 rs2001328 chr8:10987199 T/C cg21775007 chr8:11205619 TDH -0.55 -5.05 -0.41 1.53e-6 Triglycerides; TGCT cis rs7666738 0.830 rs11727235 chr4:98946331 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9457247 1.000 rs415842 chr6:167406681 G/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs6586111 1.000 rs7097564 chr10:82372188 T/C cg03086067 chr10:82368399 SH2D4B -0.24 -4.7 -0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs9902453 0.868 rs7212162 chr17:28321328 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.01 0.58 7.28e-13 Coffee consumption (cups per day); TGCT cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.73 7.52 0.56 9.57e-12 Blood metabolite levels; TGCT cis rs7267979 1.000 rs6050602 chr20:25401203 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17767294 0.614 rs41269291 chr6:28251539 A/G cg08851530 chr6:28072375 NA 1.54 6.89 0.53 2.51e-10 Parkinson's disease; TGCT cis rs9916302 0.904 rs57399933 chr17:37551189 A/G cg07936489 chr17:37558343 FBXL20 0.63 4.84 0.4 3.76e-6 Glomerular filtration rate (creatinine); TGCT cis rs2456568 0.548 rs1607402 chr11:93660732 T/G cg17595323 chr11:93583763 C11orf90 -0.42 -5.14 -0.42 1.03e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg16049864 chr8:95962084 TP53INP1 -0.58 -7.09 -0.54 9.12e-11 Type 2 diabetes; TGCT cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg07507251 chr3:52567010 NT5DC2 0.46 6.68 0.51 7.37e-10 Bipolar disorder; TGCT cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs4819052 0.851 rs1999335 chr21:46670613 A/G cg06618935 chr21:46677482 NA -0.38 -5.69 -0.45 8.75e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7147624 1.000 rs10083363 chr14:66200768 G/A cg03016385 chr14:66212404 NA -0.5 -7.04 -0.53 1.13e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2456568 0.802 rs8181567 chr11:93637209 C/T cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.09e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7833790 0.724 rs10958045 chr8:82722994 T/C cg23324259 chr8:82754387 SNX16 -0.61 -4.71 -0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs877282 0.786 rs11253392 chr10:788768 G/A cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg03407747 chr17:6899364 ALOX12 -0.49 -5.55 -0.45 1.61e-7 Tonsillectomy; TGCT cis rs2541522 0.600 rs8057438 chr16:10744907 G/C cg21839338 chr16:10912331 FAM18A 0.4 4.48 0.37 1.65e-5 Gut microbiome composition (summer); TGCT cis rs68170813 0.559 rs6967638 chr7:106929356 T/G cg02696742 chr7:106810147 HBP1 -0.68 -5.69 -0.46 8.53e-8 Coronary artery disease; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg11905131 chr22:24372483 LOC391322 0.66 5.2 0.42 7.88e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6545883 0.718 rs2694624 chr2:61672313 C/A cg15711740 chr2:61764176 XPO1 -0.54 -4.93 -0.4 2.62e-6 Tuberculosis; TGCT cis rs875971 1.000 rs4718307 chr7:65610988 A/G cg11764359 chr7:65958608 NA -0.59 -5.28 -0.43 5.5e-7 Aortic root size; TGCT cis rs11673344 0.523 rs2562607 chr19:37522260 A/G cg08039142 chr19:36980659 ZNF566 0.5 4.64 0.38 8.58e-6 Obesity-related traits; TGCT cis rs6867032 0.527 rs4246752 chr5:1975575 T/A cg05184729 chr5:1962311 NA 0.28 4.75 0.39 5.57e-6 Gut microbiome composition (winter); TGCT cis rs1775715 0.705 rs2778651 chr10:32106575 C/T cg14930904 chr10:32216787 ARHGAP12 0.5 4.85 0.4 3.62e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs7586879 0.828 rs12986610 chr2:25106265 A/G cg01884057 chr2:25150051 NA -0.25 -4.51 -0.38 1.5e-5 Body mass index; TGCT cis rs2115630 0.967 rs28595395 chr15:85334952 T/C cg11189052 chr15:85197271 WDR73 -0.63 -6.08 -0.48 1.34e-8 P wave terminal force; TGCT cis rs2046867 0.908 rs2322610 chr3:72793651 C/A cg25664220 chr3:72788482 NA -0.55 -6.95 -0.53 1.83e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs12210905 0.688 rs12213471 chr6:27406063 C/G cg08851530 chr6:28072375 NA 1.34 6.07 0.48 1.44e-8 Hip circumference adjusted for BMI; TGCT cis rs10504229 1.000 rs67096506 chr8:58195655 G/A cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT trans rs2727020 0.521 rs11040377 chr11:49474346 T/C cg15704280 chr7:45808275 SEPT13 -0.64 -7.11 -0.54 8.23e-11 Coronary artery disease; TGCT cis rs1018836 0.923 rs9694450 chr8:91618292 G/A cg16814680 chr8:91681699 NA -0.91 -9.64 -0.65 9.57e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs3125734 0.719 rs3852410 chr10:64037563 A/G cg19640130 chr10:64028056 RTKN2 0.37 4.48 0.37 1.67e-5 Rheumatoid arthritis; TGCT cis rs17376456 0.809 rs12152763 chr5:93405509 T/A cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs8177253 0.901 rs9843728 chr3:133501407 C/T cg08439880 chr3:133502540 NA -0.33 -6.28 -0.49 5.28e-9 Iron status biomarkers; TGCT cis rs1371867 0.875 rs1788184 chr8:101335106 A/G cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs2180341 0.538 rs3756993 chr6:127651551 A/C cg24812749 chr6:127587940 RNF146 0.63 5.32 0.43 4.67e-7 Breast cancer; TGCT cis rs3935685 0.874 rs11072665 chr15:78006256 T/C cg03457338 chr15:78040120 NA -0.22 -5.59 -0.45 1.37e-7 Intelligence (multi-trait analysis); TGCT cis rs2073300 1.000 rs6048833 chr20:23462185 G/A cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.28 0.49 5.19e-9 Schizophrenia; TGCT cis rs11785400 0.762 rs7017931 chr8:143726728 A/G cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs2688608 0.620 rs12253408 chr10:75495956 G/T cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs2204008 0.720 rs11180923 chr12:38255172 A/T cg13010199 chr12:38710504 ALG10B 0.61 4.67 0.39 7.69e-6 Bladder cancer; TGCT cis rs13242816 1.000 rs2052105 chr7:116187979 T/C cg16553024 chr7:116138462 CAV2 -0.45 -5.3 -0.43 5.1e-7 P wave duration; TGCT cis rs17401966 0.838 rs1556916 chr1:10403482 G/A cg19773385 chr1:10388646 KIF1B -0.23 -5.38 -0.44 3.57e-7 Hepatocellular carcinoma; TGCT cis rs3892630 0.878 rs2903759 chr19:33195947 A/G cg22980127 chr19:33182716 NUDT19 0.7 5.18 0.42 8.9e-7 Red blood cell traits; TGCT cis rs7843479 0.930 rs2054713 chr8:21840534 A/G cg17168535 chr8:21777572 XPO7 0.63 5.73 0.46 7.05e-8 Mean corpuscular volume; TGCT cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg07636037 chr3:49044803 WDR6 0.85 8.85 0.62 7.4e-15 Menarche (age at onset); TGCT cis rs2153535 0.580 rs763376 chr6:8492776 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6089584 0.893 rs6089306 chr20:60574868 G/A cg06108461 chr20:60628389 TAF4 -0.58 -8.21 -0.59 2.37e-13 Body mass index; TGCT cis rs2153535 0.580 rs9378552 chr6:8463748 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1008375 0.966 rs6839660 chr4:17667987 C/T cg16339924 chr4:17578868 LAP3 0.56 4.91 0.4 2.78e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11247915 0.644 rs11588739 chr1:26653319 G/A cg23732845 chr1:26663426 AIM1L -0.34 -4.44 -0.37 1.95e-5 Obesity-related traits; TGCT cis rs2361710 0.611 rs12451471 chr17:78102517 C/T cg09238746 chr17:78121135 EIF4A3 -0.59 -4.75 -0.39 5.6e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs7772486 0.754 rs1055212 chr6:146058315 A/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.66 -0.39 8.17e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs62380364 0.602 rs610217 chr5:88065263 G/A cg22951263 chr5:87985283 NA -0.6 -6.34 -0.49 3.84e-9 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.791 rs6570693 chr6:145910841 C/T cg05347473 chr6:146136440 FBXO30 0.51 4.75 0.39 5.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4812048 0.602 rs59637156 chr20:57619618 T/C cg14073986 chr20:57617431 SLMO2 0.54 4.48 0.37 1.66e-5 Mean platelet volume; TGCT cis rs11098499 0.954 rs2306455 chr4:120421969 G/A cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs612683 0.517 rs3767832 chr1:100943100 A/G cg06223162 chr1:101003688 GPR88 -0.31 -5.58 -0.45 1.41e-7 Breast cancer; TGCT cis rs3785574 0.962 rs35448669 chr17:61938923 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.52 0.44 1.86e-7 Height; TGCT cis rs4733781 0.863 rs6470805 chr8:131161571 A/G cg16277922 chr8:131349729 ASAP1 0.39 4.87 0.4 3.3e-6 Tuberculosis; TGCT cis rs9894429 0.966 rs6565601 chr17:79580173 C/T cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs2842992 0.724 rs15982 chr6:160199687 T/C cg11366901 chr6:160182831 ACAT2 0.74 5.59 0.45 1.36e-7 Age-related macular degeneration (geographic atrophy); TGCT cis rs9549367 0.789 rs71446679 chr13:113894821 C/T cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs1878931 0.507 rs34370895 chr16:3396319 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -5.09 -0.42 1.28e-6 Body mass index (adult); TGCT cis rs7945705 0.967 rs56316046 chr11:8876598 G/T cg21881798 chr11:8931708 C11orf17;ST5 0.44 5.04 0.41 1.59e-6 Hemoglobin concentration; TGCT cis rs4862750 0.914 rs11943333 chr4:187872455 A/G cg11301795 chr4:187892539 NA -0.34 -4.97 -0.41 2.17e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs595982 0.527 rs17272673 chr19:49362992 C/A cg21252483 chr19:49399788 TULP2 -0.43 -6.54 -0.51 1.48e-9 Red cell distribution width; TGCT cis rs8180040 0.620 rs4683322 chr3:47093189 T/C cg27129171 chr3:47204927 SETD2 0.71 8.55 0.61 3.9e-14 Colorectal cancer; TGCT cis rs7172809 0.897 rs74026930 chr15:77825253 G/A cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs6589563 0.609 rs57641217 chr11:116632956 C/T cg20660624 chr11:117307972 DSCAML1 -0.35 -4.65 -0.39 8.34e-6 Eosinophil counts; TGCT cis rs1362404 0.552 rs2192858 chr16:51992615 C/T cg03955530 chr16:52681474 NA 0.3 4.81 0.4 4.38e-6 Gut microbiota (bacterial taxa); TGCT cis rs9372498 0.536 rs9481833 chr6:118919631 G/A cg07617317 chr6:118971624 C6orf204 0.49 5.22 0.42 7.37e-7 Diastolic blood pressure; TGCT cis rs9443645 0.836 rs9352676 chr6:79629999 A/G cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs7845219 0.525 rs6471501 chr8:95922491 A/G cg16049864 chr8:95962084 TP53INP1 -0.51 -5.45 -0.44 2.56e-7 Type 2 diabetes; TGCT cis rs7586879 0.639 rs13407913 chr2:25097644 A/G cg01884057 chr2:25150051 NA 0.31 5.94 0.47 2.72e-8 Body mass index; TGCT cis rs6089584 0.854 rs8117075 chr20:60613766 T/C cg16423285 chr20:60520624 NA -0.61 -6.46 -0.5 2.12e-9 Body mass index; TGCT cis rs12541335 0.639 rs4872468 chr8:22179844 G/C cg02788857 chr8:22132959 PIWIL2 0.28 5.13 0.42 1.1e-6 Hypertriglyceridemia; TGCT cis rs4494114 1.000 rs9439081 chr1:39343012 A/G cg25970120 chr1:39325951 RRAGC -0.58 -5.93 -0.47 2.84e-8 Blood protein levels; TGCT cis rs7582180 0.764 rs4635546 chr2:100921125 G/A cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs1153858 1.000 rs67744121 chr15:45677237 C/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs62064224 0.638 rs9748130 chr17:30739113 A/G cg18200150 chr17:30822561 MYO1D 0.41 4.92 0.4 2.72e-6 Schizophrenia; TGCT cis rs875971 0.756 rs2901210 chr7:66017505 G/A cg11764359 chr7:65958608 NA -0.55 -5.12 -0.42 1.14e-6 Aortic root size; TGCT cis rs265548 0.608 rs36690 chr19:17910483 C/T cg04517722 chr19:17905589 B3GNT3 0.49 6.48 0.5 1.93e-9 Tumor biomarkers; TGCT cis rs999943 0.774 rs10947421 chr6:33611278 G/T cg14003231 chr6:33640908 ITPR3 0.39 4.9 0.4 2.97e-6 Obesity (extreme); TGCT cis rs7208859 0.623 rs28627615 chr17:29145817 G/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs644799 1.000 rs488246 chr11:95560473 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs7104764 0.917 rs1045288 chr11:237087 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs2637266 1.000 rs2395389 chr10:78357701 C/T cg18941641 chr10:78392320 NA 0.37 4.5 0.37 1.53e-5 Pulmonary function; TGCT cis rs60843830 1.000 rs55936726 chr2:258210 T/C cg00108164 chr2:264199 ACP1;SH3YL1 0.71 6.83 0.52 3.39e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs6582630 0.519 rs7305570 chr12:38349285 G/A cg13010199 chr12:38710504 ALG10B 0.58 4.52 0.38 1.41e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs763014 0.833 rs916415 chr16:632115 G/A cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs4901869 0.966 rs431343 chr14:59345530 C/T cg02291164 chr14:59296302 NA 0.25 4.82 0.4 4.11e-6 Panic disorder; TGCT cis rs6921919 0.583 rs7764722 chr6:28354533 C/T cg13525197 chr6:28411240 ZSCAN23 -0.5 -4.52 -0.38 1.42e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs61897795 0.628 rs174597 chr11:61621040 G/C cg19610905 chr11:61596333 FADS2 -0.62 -4.65 -0.39 8.27e-6 Neutrophil count;Sum basophil neutrophil counts; TGCT cis rs319204 1.000 rs319217 chr5:146253893 T/C cg13983063 chr5:146258615 PPP2R2B 0.32 4.6 0.38 1.04e-5 Schizophrenia; TGCT cis rs12711979 0.509 rs10187740 chr2:3823965 A/G cg17052675 chr2:3827356 NA 0.55 12.73 0.75 2.94e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs3845702 0.736 rs12465592 chr2:180862654 C/G cg01881094 chr2:180872142 CWC22 1.06 6.66 0.51 8.12e-10 Schizophrenia; TGCT cis rs155076 1.000 rs261430 chr13:21865242 C/T cg14456004 chr13:21872349 NA -1.23 -9.97 -0.67 1.49e-17 White matter hyperintensity burden; TGCT trans rs1005277 0.522 rs289648 chr10:37971837 T/C cg17830980 chr10:43048298 ZNF37B -0.66 -7.47 -0.56 1.22e-11 Extrinsic epigenetic age acceleration; TGCT cis rs2120019 1.000 rs1867146 chr15:75354971 C/G cg09165964 chr15:75287851 SCAMP5 -1.18 -9.83 -0.66 3.33e-17 Blood trace element (Zn levels); TGCT cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg24829409 chr8:58192753 C8orf71 -0.54 -5.17 -0.42 9.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.851 rs6089827 chr20:61668845 C/T cg08045932 chr20:61659980 NA 0.48 9.09 0.63 2.04e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs8177179 0.967 rs4287912 chr3:133437778 A/G cg24879335 chr3:133465180 TF 0.36 4.79 0.4 4.67e-6 Iron status biomarkers (transferrin levels); TGCT cis rs6429082 0.818 rs291383 chr1:235643100 G/A cg26050004 chr1:235667680 B3GALNT2 0.62 5.58 0.45 1.43e-7 Adiposity; TGCT trans rs7824557 0.547 rs6601570 chr8:11079367 G/A cg15556689 chr8:8085844 FLJ10661 -0.89 -8.62 -0.61 2.69e-14 Retinal vascular caliber; TGCT cis rs10510102 0.872 rs11200292 chr10:123726898 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg00786635 chr1:25594202 NA 0.54 5.72 0.46 7.45e-8 Erythrocyte sedimentation rate; TGCT cis rs7944584 0.611 rs10838696 chr11:47363285 A/G cg20307385 chr11:47447363 PSMC3 -0.82 -8.29 -0.6 1.55e-13 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs9302001 0.920 rs9516479 chr13:95459936 C/T cg07483244 chr13:95358924 NA 0.37 4.81 0.4 4.22e-6 Panic disorder; TGCT cis rs7845219 0.544 rs9643352 chr8:95918288 C/T cg13393036 chr8:95962371 TP53INP1 -0.45 -5.18 -0.42 8.66e-7 Type 2 diabetes; TGCT cis rs7523050 0.558 rs35926243 chr1:109407712 T/A cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs61990749 0.597 rs1477260 chr14:78256818 G/C cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs7511006 0.895 rs5771270 chr22:50682865 G/A cg08875078 chr22:50639485 SELO 0.51 4.73 0.39 5.99e-6 Obesity-related traits; TGCT trans rs6762477 0.715 rs12631337 chr3:50198537 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.49 -0.65 2.16e-16 Menarche (age at onset); TGCT cis rs2688608 0.592 rs10824032 chr10:75528130 G/A cg19442545 chr10:75533431 FUT11 -0.35 -5.66 -0.45 9.97e-8 Inflammatory bowel disease; TGCT cis rs7100689 0.622 rs4933378 chr10:82147057 T/C cg01528321 chr10:82214614 TSPAN14 0.79 7.93 0.58 1.11e-12 Post bronchodilator FEV1; TGCT cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg11644478 chr21:40555479 PSMG1 1.02 11.02 0.7 4.19e-20 Cognitive function; TGCT cis rs362272 0.545 rs2236052 chr4:3318413 C/T cg22655196 chr4:3374909 RGS12 -0.24 -4.98 -0.41 2.07e-6 Serum sulfate level; TGCT cis rs11578119 0.866 rs12140680 chr1:170353228 C/G cg09767346 chr1:170501363 GORAB 0.61 4.61 0.38 9.8e-6 Male-pattern baldness; TGCT cis rs4975709 0.589 rs4975707 chr5:1864028 C/T cg07747251 chr5:1868357 NA 0.39 5.66 0.45 9.96e-8 Cardiovascular disease risk factors; TGCT cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg19318889 chr4:1322082 MAEA 0.27 6.54 0.51 1.45e-9 Longevity; TGCT cis rs9916302 0.653 rs11654954 chr17:37745979 C/T cg07936489 chr17:37558343 FBXL20 0.68 5.35 0.43 4.11e-7 Glomerular filtration rate (creatinine); TGCT cis rs2153535 0.580 rs2327051 chr6:8441150 A/G cg07606381 chr6:8435919 SLC35B3 -0.51 -4.57 -0.38 1.18e-5 Motion sickness; TGCT cis rs4930103 0.619 rs739905 chr11:1980360 G/C cg18032502 chr11:1949113 TNNT3 0.25 4.72 0.39 6.27e-6 DNA methylation (parent-of-origin);DNA methylation (variation); TGCT cis rs854765 0.624 rs12952723 chr17:17731651 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.68 -6.35 -0.5 3.78e-9 Total body bone mineral density; TGCT cis rs11249608 0.548 rs13161528 chr5:178452958 C/G cg21905437 chr5:178450457 ZNF879 0.43 4.5 0.37 1.53e-5 Pubertal anthropometrics; TGCT cis rs7698623 0.850 rs2045834 chr4:88800642 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.78 -0.39 4.95e-6 Cardiovascular disease risk factors; TGCT cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg08219700 chr8:58056026 NA 0.38 4.61 0.38 1e-5 Developmental language disorder (linguistic errors); TGCT cis rs682748 0.810 rs62349987 chr5:17108579 T/C cg23987134 chr5:17158319 LOC285696 -0.2 -4.76 -0.39 5.33e-6 Hippocampal atrophy; TGCT cis rs9814567 0.752 rs7649910 chr3:134241310 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.89 -0.66 2.32e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs17384381 0.953 rs12122816 chr1:85792384 C/T cg16011679 chr1:85725395 C1orf52 0.81 6.34 0.49 3.82e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs903263 0.562 rs35452337 chr1:84534503 C/A cg09664975 chr1:84543551 PRKACB 0.48 4.75 0.39 5.42e-6 Breast cancer (male); TGCT trans rs4650994 0.525 rs4651000 chr1:178532223 A/G cg05059571 chr16:84539110 KIAA1609 -0.54 -11.05 -0.7 3.58e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs514406 0.505 rs427319 chr1:53178807 T/G cg01802117 chr1:53393560 SCP2 -0.4 -4.75 -0.39 5.55e-6 Monocyte count; TGCT cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg20999797 chr1:1681921 NA 0.18 4.69 0.39 7.02e-6 Body mass index; TGCT cis rs778371 0.697 rs6717048 chr2:233586427 T/C cg08000102 chr2:233561755 GIGYF2 0.75 9.07 0.63 2.27e-15 Schizophrenia; TGCT cis rs35934224 0.831 rs8141610 chr22:19870147 A/G cg11182965 chr22:19864308 TXNRD2 0.36 5.08 0.41 1.37e-6 Glaucoma (primary open-angle); TGCT cis rs2486288 0.539 rs2433601 chr15:45716425 T/C cg14582100 chr15:45693742 SPATA5L1 0.43 5.38 0.44 3.52e-7 Glomerular filtration rate; TGCT cis rs2180341 0.782 rs4897214 chr6:127723625 G/T cg24812749 chr6:127587940 RNF146 0.65 5.19 0.42 8.37e-7 Breast cancer; TGCT cis rs597539 0.652 rs604524 chr11:68629929 G/A cg06112835 chr11:68658793 MRPL21 0.48 8.42 0.6 7.63e-14 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs8141529 0.764 rs5762854 chr22:29246278 T/C cg02153584 chr22:29168773 CCDC117 0.65 5.49 0.44 2.2e-7 Lymphocyte counts; TGCT cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs6546537 0.550 rs4852272 chr2:69776730 C/T cg10773587 chr2:69614142 GFPT1 -0.76 -7.08 -0.54 9.55e-11 Serum thyroid-stimulating hormone levels; TGCT cis rs9916302 0.904 rs11078910 chr17:37671269 G/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.92 -0.4 2.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs17376456 0.877 rs10055340 chr5:93317644 T/C cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs10504229 0.679 rs12375445 chr8:58040082 A/G cg08280861 chr8:58055591 NA 0.35 4.92 0.4 2.72e-6 Developmental language disorder (linguistic errors); TGCT trans rs208520 0.690 rs1580430 chr6:66715162 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.13 0.71 2.27e-20 Exhaled nitric oxide output; TGCT cis rs7147624 1.000 rs8021889 chr14:66214811 A/G cg03016385 chr14:66212404 NA -0.5 -7.11 -0.54 8.15e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2239815 0.545 rs5762855 chr22:29246605 A/T cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs832540 1.000 rs252914 chr5:56198150 A/C cg12311346 chr5:56204834 C5orf35 -0.49 -5.15 -0.42 9.94e-7 Coronary artery disease; TGCT cis rs2180341 1.000 rs6569477 chr6:127589302 T/A cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs1552244 0.572 rs113406084 chr3:10170190 T/C cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs10875595 0.836 rs1363453 chr5:140657864 G/A cg24830062 chr5:140700576 TAF7 -0.6 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs9814567 1.000 rs13322305 chr3:134310791 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9902453 0.619 rs2244585 chr17:28072176 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -7.97 -0.58 8.91e-13 Coffee consumption (cups per day); TGCT cis rs7772486 0.624 rs9485018 chr6:146025731 T/C cg23711669 chr6:146136114 FBXO30 -0.88 -9.77 -0.66 4.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10771431 0.967 rs7137443 chr12:9372029 C/T cg09152401 chr12:9436616 LOC642846 -0.56 -5.68 -0.45 9.1e-8 Breast size; TGCT cis rs7833790 0.963 rs10958046 chr8:82729210 A/G cg27398817 chr8:82754497 SNX16 -0.84 -5.98 -0.47 2.18e-8 Diastolic blood pressure; TGCT cis rs12510870 0.565 rs10016403 chr4:74399407 C/T cg05868023 chr4:75230803 EREG 0.56 5.14 0.42 1.06e-6 Iris color (b* coordinate); TGCT cis rs68170813 0.559 rs79778437 chr7:107004972 T/A cg02696742 chr7:106810147 HBP1 -0.71 -5.96 -0.47 2.38e-8 Coronary artery disease; TGCT cis rs6545883 0.929 rs12617911 chr2:61740825 A/G cg15711740 chr2:61764176 XPO1 -0.56 -5.17 -0.42 9.02e-7 Tuberculosis; TGCT cis rs35306767 0.855 rs55697724 chr10:885622 T/C cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs6540559 0.673 rs17015218 chr1:209967915 A/G cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs7819412 1.000 rs7819412 chr8:11045161 A/G cg27411982 chr8:10470053 RP1L1 0.21 4.62 0.38 9.61e-6 Triglycerides; TGCT cis rs858239 0.665 rs858306 chr7:23242754 A/T cg05602783 chr7:23145260 KLHL7 -0.63 -5.21 -0.42 7.52e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs17293817 0.650 rs12778422 chr10:1413776 A/G cg02408697 chr10:1416920 ADARB2 0.39 4.52 0.38 1.42e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs548987 0.529 rs1165164 chr6:25863481 G/A cg03264133 chr6:25882463 NA -0.61 -5.16 -0.42 9.63e-7 Homocysteine levels; TGCT cis rs17331151 0.505 rs71299610 chr3:52641703 T/G cg15956490 chr3:53032818 SFMBT1 0.7 5.71 0.46 7.8e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2282802 0.585 rs2189659 chr5:139697220 C/A cg01081189 chr5:139537190 NA -0.27 -5.01 -0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs6967414 0.681 rs2881352 chr7:6753511 T/A cg00387323 chr7:6746715 ZNF12 0.77 4.73 0.39 6.05e-6 Hematocrit;Hemoglobin concentration; TGCT trans rs2727020 0.576 rs10839305 chr11:49598733 T/C cg15704280 chr7:45808275 SEPT13 -0.75 -8.9 -0.62 5.74e-15 Coronary artery disease; TGCT cis rs12458462 0.812 rs34583578 chr18:77491070 C/T cg11879182 chr18:77439856 CTDP1 0.7 7.99 0.58 7.93e-13 Monocyte count; TGCT cis rs1218582 0.772 rs4845400 chr1:154872523 C/T cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg12311346 chr5:56204834 C5orf35 -0.63 -6.36 -0.5 3.5e-9 Initial pursuit acceleration; TGCT cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.695 rs62541532 chr9:5017384 C/A cg02405213 chr9:5042618 JAK2 -0.71 -9.1 -0.63 1.89e-15 Pediatric autoimmune diseases; TGCT cis rs9325144 0.555 rs6582607 chr12:38717678 T/C cg26384229 chr12:38710491 ALG10B -0.63 -5.91 -0.47 3.03e-8 Morning vs. evening chronotype; TGCT cis rs9818758 0.607 rs35060561 chr3:49255503 T/C cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.831 rs2836921 chr21:40516070 C/T cg11644478 chr21:40555479 PSMG1 1.0 10.38 0.68 1.5e-18 Cognitive function; TGCT cis rs2677744 0.597 rs16945091 chr15:91499081 A/T cg23684204 chr15:91497937 RCCD1 0.39 6.08 0.48 1.39e-8 Attention deficit hyperactivity disorder; TGCT cis rs13082711 0.516 rs1492339 chr3:27371526 A/C cg02860705 chr3:27208620 NA -0.29 -4.44 -0.37 1.95e-5 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs4720575 0.839 rs10255464 chr7:47097043 A/G cg00036614 chr7:47093842 NA -0.21 -5.35 -0.43 4.1e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs7772486 0.875 rs10872583 chr6:146396699 G/T cg05347473 chr6:146136440 FBXO30 -0.54 -4.99 -0.41 2.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg06481639 chr22:41940642 POLR3H -0.63 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs3784262 0.528 rs8027964 chr15:58335272 C/T cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.47 -0.5 2.08e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9894429 0.646 rs12948797 chr17:79617384 G/A cg18240062 chr17:79603768 NPLOC4 0.56 4.89 0.4 3e-6 Eye color traits; TGCT cis rs62380364 0.701 rs304136 chr5:88170066 T/C cg22951263 chr5:87985283 NA 0.52 5.22 0.42 7.17e-7 Intelligence (multi-trait analysis); TGCT cis rs3733631 1.000 rs11943988 chr4:104654699 A/G cg24090629 chr4:104641072 TACR3 -0.77 -6.29 -0.49 4.9e-9 Menarche (age at onset); TGCT cis rs7542091 0.704 rs2142907 chr1:210039505 T/C cg23283495 chr1:209979779 IRF6 0.56 5.59 0.45 1.36e-7 Monobrow; TGCT cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12286929 0.639 rs4938180 chr11:115041012 C/T cg04017736 chr11:115827165 NA -0.2 -4.46 -0.37 1.78e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2404602 0.647 rs12904417 chr15:76964152 A/G cg23625390 chr15:77176239 SCAPER 0.36 4.56 0.38 1.21e-5 Blood metabolite levels; TGCT cis rs7772486 0.754 rs697055 chr6:146003790 C/G cg23711669 chr6:146136114 FBXO30 0.91 10.65 0.69 3.23e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs2235642 0.826 rs8048410 chr16:1614097 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.32 -4.95 -0.41 2.39e-6 Coronary artery disease; TGCT cis rs9467773 1.000 rs9461259 chr6:26504835 C/A cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.675 rs2736265 chr8:11186674 A/G cg21775007 chr8:11205619 TDH 0.7 6.77 0.52 4.48e-10 Retinal vascular caliber; TGCT cis rs7647973 0.588 rs9883000 chr3:49667691 A/G cg03060546 chr3:49711283 APEH 0.62 5.35 0.43 4.12e-7 Menarche (age at onset); TGCT cis rs7267979 0.966 rs6050532 chr20:25308793 A/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg13607699 chr17:42295918 UBTF -0.59 -5.39 -0.44 3.37e-7 Total body bone mineral density; TGCT cis rs2070488 0.965 rs6599206 chr3:38545349 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.85 -8.67 -0.61 2.01e-14 Electrocardiographic conduction measures; TGCT cis rs7666738 0.546 rs17546687 chr4:98769266 T/A cg17366294 chr4:99064904 C4orf37 0.61 5.7 0.46 8.38e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg22963979 chr7:1858916 MAD1L1 -0.35 -5.5 -0.44 2.08e-7 Bipolar disorder and schizophrenia; TGCT cis rs9894429 0.646 rs12603868 chr17:79618834 G/C cg21028142 chr17:79581711 NPLOC4 0.29 5.91 0.47 3.09e-8 Eye color traits; TGCT cis rs9910055 0.762 rs2526020 chr17:42216588 G/T cg13607699 chr17:42295918 UBTF 0.83 7.64 0.57 5.01e-12 Total body bone mineral density; TGCT cis rs4819052 0.851 rs28622522 chr21:46676599 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7119038 0.779 rs11217045 chr11:118697865 C/A cg19308663 chr11:118741387 NA 0.3 5.88 0.47 3.49e-8 Sjögren's syndrome; TGCT cis rs155076 1.000 rs2478824 chr13:21844144 G/C cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs9527 0.590 rs11191513 chr10:104772984 T/G cg15744005 chr10:104629667 AS3MT -0.42 -4.92 -0.4 2.74e-6 Arsenic metabolism; TGCT cis rs7100689 0.622 rs1417221 chr10:82100428 G/A cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs9611565 0.512 rs2050033 chr22:42159229 G/T cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs41271473 0.706 rs72763990 chr1:228719071 A/T cg04850211 chr1:228464232 OBSCN -0.7 -4.46 -0.37 1.79e-5 Chronic lymphocytic leukemia; TGCT cis rs7226408 0.857 rs11662905 chr18:34433270 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs11098499 0.554 rs2175381 chr4:120265967 T/C cg09307838 chr4:120376055 NA 0.56 5.49 0.44 2.18e-7 Corneal astigmatism; TGCT cis rs1048238 0.506 rs7552077 chr1:16196759 A/G cg21385522 chr1:16154831 NA 0.58 6.76 0.52 4.89e-10 Systolic blood pressure; TGCT cis rs7769051 0.711 rs7738071 chr6:133085116 G/A cg22852734 chr6:133119734 C6orf192 1.26 6.8 0.52 3.97e-10 Type 2 diabetes nephropathy; TGCT cis rs3617 0.573 rs3821873 chr3:52913006 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.79 -0.39 4.73e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg16325326 chr1:53192061 ZYG11B 0.63 7.34 0.55 2.51e-11 Monocyte count; TGCT cis rs1475911 0.947 rs67055914 chr21:43510427 T/C cg19766460 chr21:43528205 UMODL1;C21orf128 0.52 7.1 0.54 8.32e-11 IgG glycosylation; TGCT cis rs11627546 0.571 rs61980575 chr14:70363900 G/T cg10496350 chr14:71275911 MAP3K9 -0.88 -4.49 -0.37 1.59e-5 Red blood cell traits; TGCT cis rs10876993 0.928 rs2640636 chr12:58077544 A/G cg15848620 chr12:58087721 OS9 -0.71 -5.77 -0.46 5.92e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.56 4.97 0.41 2.19e-6 Height; TGCT cis rs698833 0.509 rs12987415 chr2:44530423 C/T cg23552047 chr2:44669647 C2orf34 0.28 4.53 0.38 1.36e-5 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs2486288 0.656 rs11629859 chr15:45547121 T/G cg26924012 chr15:45694286 SPATA5L1 -0.7 -6.77 -0.52 4.55e-10 Glomerular filtration rate; TGCT cis rs7178572 0.568 rs11636554 chr15:77608747 C/T cg22256960 chr15:77711686 NA -0.87 -9.11 -0.63 1.74e-15 Type 2 diabetes; TGCT cis rs950169 0.922 rs12906983 chr15:84931022 G/A cg12863693 chr15:85201151 NMB 0.46 4.97 0.41 2.13e-6 Schizophrenia; TGCT cis rs4851266 0.898 rs13026143 chr2:100865406 A/G cg07810366 chr2:100720526 AFF3 0.35 5.01 0.41 1.87e-6 Educational attainment; TGCT cis rs597539 0.652 rs592697 chr11:68650064 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.13 0.59 3.82e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7824557 0.679 rs6991074 chr8:11136046 T/C cg21775007 chr8:11205619 TDH -0.59 -5.38 -0.44 3.52e-7 Retinal vascular caliber; TGCT cis rs1448094 0.511 rs17345975 chr12:86202318 T/A cg02569458 chr12:86230093 RASSF9 0.4 5.08 0.42 1.32e-6 Major depressive disorder; TGCT cis rs2404602 0.716 rs17364076 chr15:76760891 C/T cg26408565 chr15:76604113 ETFA -0.39 -5.24 -0.43 6.74e-7 Blood metabolite levels; TGCT cis rs4699052 0.893 rs4699058 chr4:104171321 T/A cg16532752 chr4:104119610 CENPE -0.52 -4.76 -0.39 5.34e-6 Testicular germ cell tumor; TGCT cis rs11792861 0.962 rs11789624 chr9:111796231 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.47 0.37 1.77e-5 Menarche (age at onset); TGCT cis rs7666738 0.830 rs9995386 chr4:98907826 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.88 0.4 3.2e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs634534 0.622 rs1308733 chr11:65720841 T/C cg17985854 chr11:65770987 BANF1;EIF1AD -0.22 -4.71 -0.39 6.65e-6 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs12134133 1.000 rs55638602 chr1:207428942 C/T cg02152968 chr1:207494213 CD55 0.61 4.83 0.4 3.92e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs76878669 0.561 rs1784029 chr11:66099987 C/T cg18002602 chr11:66138449 SLC29A2 0.53 6.5 0.5 1.77e-9 Educational attainment (years of education); TGCT cis rs4237845 0.537 rs10747786 chr12:58260601 G/T cg23860436 chr12:58378763 NA 0.33 4.61 0.38 1e-5 Intelligence (multi-trait analysis); TGCT cis rs739401 0.611 rs572373 chr11:3055361 T/C cg05729581 chr11:3078854 CARS -0.55 -5.15 -0.42 9.85e-7 Longevity; TGCT cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg17264618 chr3:40429014 ENTPD3 0.33 4.71 0.39 6.52e-6 Renal cell carcinoma; TGCT cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg20637647 chr7:64974828 NA -0.88 -5.21 -0.42 7.77e-7 Diabetic kidney disease; TGCT cis rs7666738 0.515 rs28615369 chr4:98896858 C/T cg17366294 chr4:99064904 C4orf37 0.63 5.54 0.45 1.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9868809 0.505 rs28567949 chr3:48744560 G/A cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9341808 0.690 rs6930534 chr6:80896050 C/T cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs2075371 0.829 rs727202 chr7:133947942 A/G cg11752832 chr7:134001865 SLC35B4 0.66 5.51 0.44 1.95e-7 Mean platelet volume; TGCT cis rs9611565 0.649 rs202614 chr22:41822150 A/C cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs17376456 0.877 rs56373208 chr5:93491276 C/A cg25358565 chr5:93447407 FAM172A 0.97 8.32 0.6 1.34e-13 Diabetic retinopathy; TGCT cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg05738196 chr6:26577821 NA 0.88 11.09 0.71 2.86e-20 Intelligence (multi-trait analysis); TGCT cis rs137699 0.652 rs2413589 chr22:39755689 C/T cg24399712 chr22:39784796 NA 0.65 5.66 0.45 1.01e-7 IgG glycosylation; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg24846343 chr22:24311635 DDTL 0.23 5.79 0.46 5.54e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4975616 0.869 rs401681 chr5:1322087 C/T cg00059399 chr5:2008272 NA -0.27 -4.44 -0.37 2e-5 Lung cancer; TGCT cis rs4975709 0.610 rs4975706 chr5:1860365 G/T cg14773178 chr5:1868261 NA 0.34 5.77 0.46 6.08e-8 Cardiovascular disease risk factors; TGCT cis rs10279301 1 rs10279301 chr7:156261315 C/T cg02321112 chr7:156810523 NA -0.38 -4.64 -0.38 8.89e-6 Response to bronchodilator in chronic obstructive pulmonary disease (change in FEV1); TGCT trans rs2727020 0.553 rs4980447 chr11:49591662 T/C cg11707556 chr5:10655725 ANKRD33B -0.41 -8.21 -0.59 2.4e-13 Coronary artery disease; TGCT cis rs12142240 0.698 rs6703669 chr1:46862555 C/T cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs9467711 0.790 rs10484439 chr6:26309908 G/A cg16898833 chr6:26189333 HIST1H4D 1.2 5.52 0.44 1.87e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12762955 0.608 rs7922760 chr10:1156815 G/C cg18964960 chr10:1102726 WDR37 -0.78 -6.8 -0.52 3.92e-10 Response to angiotensin II receptor blocker therapy; TGCT cis rs17152411 0.895 rs66531168 chr10:126586908 T/A cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs7193541 0.965 rs8050262 chr16:74661159 T/C cg01733217 chr16:74700730 RFWD3 0.78 7.59 0.56 6.64e-12 Multiple myeloma; TGCT cis rs1799949 1.000 rs16941 chr17:41244435 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.6e-6 Menopause (age at onset); TGCT cis rs66573146 0.831 rs73088564 chr4:6984553 G/C cg05069807 chr4:6945702 TBC1D14 0.32 5.01 0.41 1.83e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9303401 0.538 rs10515155 chr17:56481944 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.58 0.45 1.43e-7 Cognitive test performance; TGCT cis rs9894429 0.716 rs7405578 chr17:79588306 C/A cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.1e-17 Eye color traits; TGCT cis rs72781680 1.000 rs72798411 chr2:24184343 A/G cg08917208 chr2:24149416 ATAD2B 0.84 5.13 0.42 1.1e-6 Lymphocyte counts; TGCT cis rs1982963 0.950 rs61973203 chr14:52510567 A/G cg10843707 chr14:52510701 NID2 0.43 6.57 0.51 1.22e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7845219 0.544 rs9643350 chr8:95917276 C/A cg13393036 chr8:95962371 TP53INP1 -0.43 -4.95 -0.41 2.33e-6 Type 2 diabetes; TGCT cis rs4886920 0.601 rs12901558 chr15:78076379 G/A cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.37e-6 Neuroticism; TGCT cis rs4845570 0.920 rs1521185 chr1:151764049 A/G cg07092448 chr1:151763213 TDRKH 1.05 9.0 0.63 3.3e-15 Coronary artery disease; TGCT cis rs12579753 0.879 rs7131927 chr12:82166313 T/C cg21231944 chr12:82153410 PPFIA2 -0.34 -4.62 -0.38 9.52e-6 Resting heart rate; TGCT cis rs9902453 0.679 rs2054847 chr17:28532013 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.66 5.98 0.47 2.22e-8 Coffee consumption (cups per day); TGCT cis rs6754311 0.597 rs2278544 chr2:136546110 A/G cg07169764 chr2:136633963 MCM6 -0.71 -6.37 -0.5 3.33e-9 Mosquito bite size; TGCT cis rs9733 0.650 rs11204668 chr1:150543686 G/A cg13175981 chr1:150552382 MCL1 0.52 5.6 0.45 1.32e-7 Tonsillectomy; TGCT cis rs4665809 1.000 rs2053367 chr2:26293413 T/C cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs10883723 0.810 rs6584504 chr10:104253507 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT trans rs1814175 0.791 rs10839468 chr11:49986288 A/G cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs36051895 0.658 rs72699568 chr9:5007138 C/T cg02405213 chr9:5042618 JAK2 -0.8 -11.07 -0.7 3.18e-20 Pediatric autoimmune diseases; TGCT cis rs2663905 0.664 rs2460855 chr15:81361729 G/T cg18837035 chr15:81426597 C15orf26 -0.57 -4.88 -0.4 3.14e-6 QT interval (drug interaction); TGCT cis rs644799 0.601 rs7902 chr11:95565288 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.6 5.59 0.45 1.36e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs13242816 1.000 rs6979182 chr7:116119345 T/G cg16553024 chr7:116138462 CAV2 -0.44 -4.59 -0.38 1.06e-5 P wave duration; TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg09737314 chr17:6899359 ALOX12 -0.45 -4.86 -0.4 3.49e-6 Tonsillectomy; TGCT cis rs9457247 0.935 rs2757050 chr6:167377165 G/T cg25258033 chr6:167368657 RNASET2 -0.18 -4.48 -0.37 1.64e-5 Crohn's disease; TGCT cis rs3820928 0.874 rs13393894 chr2:227880543 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -4.94 -0.41 2.51e-6 Pulmonary function; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg10150615 chr22:24372951 LOC391322 0.77 8.38 0.6 9.9e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10791097 0.609 rs3751039 chr11:130773076 A/G cg05962950 chr11:130786565 SNX19 -0.95 -12.2 -0.74 5.48e-23 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.83 -9.98 -0.67 1.38e-17 Urate levels; TGCT cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT trans rs1814175 0.935 rs11040462 chr11:49683158 G/A cg15704280 chr7:45808275 SEPT13 -0.61 -6.69 -0.51 6.72e-10 Height; TGCT cis rs9677476 0.542 rs6437009 chr2:232110483 C/T cg07929768 chr2:232055508 NA -0.29 -4.49 -0.37 1.61e-5 Food antigen IgG levels; TGCT cis rs1982963 1.000 rs2029975 chr14:52506070 C/T cg10843707 chr14:52510701 NID2 -0.43 -6.6 -0.51 1.09e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2486288 0.656 rs2413771 chr15:45553140 A/G cg26924012 chr15:45694286 SPATA5L1 -0.77 -8.01 -0.58 7.01e-13 Glomerular filtration rate; TGCT cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg17971929 chr21:40555470 PSMG1 -0.71 -6.61 -0.51 1.01e-9 Cognitive function; TGCT cis rs155076 0.938 rs536209 chr13:21847714 C/T cg11317459 chr13:21872234 NA -1.42 -12.26 -0.74 4.07e-23 White matter hyperintensity burden; TGCT cis rs3892630 0.824 rs34748593 chr19:33240447 T/C cg22980127 chr19:33182716 NUDT19 0.7 5.07 0.41 1.44e-6 Red blood cell traits; TGCT cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg13395646 chr4:1353034 KIAA1530 0.39 4.84 0.4 3.81e-6 Obesity-related traits; TGCT cis rs17197710 0.673 rs61897361 chr11:47346378 G/A cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4919694 0.611 rs2271750 chr10:105174869 A/G cg04362960 chr10:104952993 NT5C2 -0.86 -5.41 -0.44 3.09e-7 Arsenic metabolism; TGCT cis rs2204008 0.677 rs1581356 chr12:38391467 T/C cg26384229 chr12:38710491 ALG10B 0.81 7.13 0.54 7.19e-11 Bladder cancer; TGCT cis rs561341 0.700 rs79272796 chr17:30226974 T/C cg13647721 chr17:30228624 UTP6 0.6 5.32 0.43 4.64e-7 Hip circumference adjusted for BMI; TGCT cis rs2239547 0.522 rs6768844 chr3:53004620 A/G cg10802521 chr3:52805072 NEK4 0.59 5.34 0.43 4.26e-7 Schizophrenia; TGCT cis rs250677 0.641 rs2915807 chr5:148450950 A/G cg18129178 chr5:148520854 ABLIM3 -0.45 -6.06 -0.48 1.54e-8 Breast cancer; TGCT cis rs698833 0.509 rs4952709 chr2:44519142 A/G cg23552047 chr2:44669647 C2orf34 0.29 4.64 0.38 8.77e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs13064447 1.000 rs13064447 chr3:12753131 C/A cg20675869 chr3:12750130 NA 0.18 4.54 0.38 1.32e-5 Major depression and alcohol dependence; TGCT cis rs2050392 0.760 rs10826797 chr10:30690376 A/C cg18806716 chr10:30721971 MAP3K8 -0.62 -8.34 -0.6 1.18e-13 Inflammatory bowel disease; TGCT cis rs7103648 0.966 rs896817 chr11:47394305 A/G cg20307385 chr11:47447363 PSMC3 -0.99 -11.78 -0.73 5.92e-22 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs8014252 0.803 rs60860517 chr14:71029919 A/C cg11204974 chr14:71022665 NA -0.53 -4.49 -0.37 1.63e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs5750830 0.594 rs6001587 chr22:39819008 T/C cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs919433 0.713 rs11900232 chr2:198466273 T/C cg00792783 chr2:198669748 PLCL1 0.48 4.47 0.37 1.75e-5 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs8031584 0.958 rs34909055 chr15:31284170 C/T cg08704250 chr15:31115839 NA -0.33 -4.55 -0.38 1.28e-5 Huntington's disease progression; TGCT cis rs7975161 0.753 rs7972034 chr12:104640881 G/T cg25273343 chr12:104657179 TXNRD1 -0.35 -4.83 -0.4 3.87e-6 Toenail selenium levels; TGCT cis rs4794106 0.792 rs847682 chr17:48208274 C/T cg13127421 chr17:48202128 SAMD14 -0.25 -6.45 -0.5 2.3e-9 Temporomandibular joint disorder; TGCT cis rs7584330 0.657 rs10190310 chr2:238352282 C/T cg14458575 chr2:238380390 NA 0.5 7.44 0.56 1.45e-11 Prostate cancer; TGCT cis rs6952808 0.575 rs6950330 chr7:1953606 T/C cg22963979 chr7:1858916 MAD1L1 -0.38 -5.73 -0.46 7.15e-8 Bipolar disorder and schizophrenia; TGCT cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg03517284 chr6:25882590 NA 0.88 8.68 0.61 1.88e-14 Blood metabolite levels; TGCT cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg04744514 chr10:134541379 INPP5A 0.25 4.47 0.37 1.73e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs4820539 1.000 rs916585 chr22:23469438 G/A cg14186256 chr22:23484241 RTDR1 0.99 12.58 0.75 6.81e-24 Bone mineral density; TGCT cis rs514406 0.607 rs6696940 chr1:53203427 C/T cg24675658 chr1:53192096 ZYG11B 0.83 10.08 0.67 8.25e-18 Monocyte count; TGCT cis rs9291683 0.618 rs13137343 chr4:10043028 C/A cg00071950 chr4:10020882 SLC2A9 0.68 8.74 0.62 1.38e-14 Bone mineral density; TGCT cis rs9640161 0.750 rs11769348 chr7:150026753 C/T cg10018233 chr7:150070692 REPIN1 -0.32 -4.59 -0.38 1.08e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs904251 0.861 rs2776875 chr6:37486796 G/C cg01843034 chr6:37503916 NA -0.52 -6.29 -0.49 4.88e-9 Cognitive performance; TGCT cis rs1878931 0.535 rs55732163 chr16:3411518 A/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.73 -6.0 -0.47 2.01e-8 Body mass index (adult); TGCT cis rs6558530 0.587 rs6986102 chr8:1700640 C/G cg09410841 chr8:1729607 CLN8 0.72 6.49 0.5 1.87e-9 Systolic blood pressure; TGCT cis rs1505368 0.836 rs10201067 chr2:213284411 A/G cg16329650 chr2:213403929 ERBB4 -0.65 -6.62 -0.51 9.53e-10 Symmetrical dimethylarginine levels; TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg27535305 chr1:53392650 SCP2 0.24 4.76 0.39 5.22e-6 Monocyte count; TGCT cis rs5751150 1 rs5751150 chr22:42153292 T/G cg06481639 chr22:41940642 POLR3H 0.69 6.02 0.48 1.83e-8 Cannabis dependence symptom count; TGCT cis rs4295623 0.556 rs10903343 chr8:11695872 T/C cg21775007 chr8:11205619 TDH 0.53 4.69 0.39 6.99e-6 Morning vs. evening chronotype; TGCT cis rs2836974 0.568 rs8130795 chr21:40549983 T/A cg11644478 chr21:40555479 PSMG1 0.64 5.77 0.46 5.84e-8 Cognitive function; TGCT cis rs6570726 0.791 rs1280276 chr6:145892350 A/C cg05347473 chr6:146136440 FBXO30 0.54 5.11 0.42 1.16e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg13695892 chr22:41940480 POLR3H -0.91 -8.85 -0.62 7.39e-15 Vitiligo; TGCT cis rs986417 0.818 rs1254325 chr14:60909689 A/G cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs2836950 0.501 rs2056844 chr21:40670460 G/C cg11644478 chr21:40555479 PSMG1 -0.52 -4.87 -0.4 3.28e-6 Menarche (age at onset); TGCT cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs42648 0.837 rs12375075 chr7:89940331 G/A cg25739043 chr7:89950458 NA -0.74 -7.35 -0.55 2.29e-11 Homocysteine levels; TGCT cis rs9916302 0.861 rs11078896 chr17:37415544 C/T cg07936489 chr17:37558343 FBXL20 -0.63 -4.99 -0.41 2.03e-6 Glomerular filtration rate (creatinine); TGCT cis rs6163 0.727 rs284854 chr10:104574562 T/G cg05855489 chr10:104503620 C10orf26 -0.64 -6.16 -0.48 9.31e-9 Waist circumference;Hip circumference; TGCT cis rs17376456 0.757 rs10476591 chr5:93333723 G/C cg25358565 chr5:93447407 FAM172A 0.97 8.43 0.6 7.5e-14 Diabetic retinopathy; TGCT cis rs910316 1.000 rs175512 chr14:75523382 T/C cg23033748 chr14:75592666 NEK9 -0.27 -4.53 -0.38 1.34e-5 Height; TGCT cis rs9329221 0.905 rs10283145 chr8:10241411 C/T cg21775007 chr8:11205619 TDH -0.54 -5.06 -0.41 1.49e-6 Neuroticism; TGCT cis rs2964802 0.505 rs7717266 chr5:10832134 C/G cg14521931 chr5:10832172 NA -0.28 -4.65 -0.39 8.37e-6 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs4906332 1.000 rs2065015 chr14:103904061 G/T cg26031613 chr14:104095156 KLC1 0.51 4.61 0.38 1e-5 Coronary artery disease; TGCT cis rs2836974 0.897 rs1571709 chr21:40553980 T/C cg17971929 chr21:40555470 PSMG1 0.96 9.05 0.63 2.44e-15 Cognitive function; TGCT cis rs13256369 0.853 rs13256216 chr8:8577883 C/T cg17143192 chr8:8559678 CLDN23 0.64 5.72 0.46 7.58e-8 Obesity-related traits; TGCT cis rs2506155 1.000 rs2506155 chr10:33503179 C/A cg25928881 chr10:32632685 EPC1 0.31 4.6 0.38 1.04e-5 Migraine; TGCT cis rs9486719 1.000 rs2472882 chr6:96863474 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs9486719 0.857 rs11759769 chr6:97065212 G/A cg18709589 chr6:96969512 KIAA0776 -0.83 -6.46 -0.5 2.16e-9 Migraine;Coronary artery disease; TGCT cis rs7552404 1.000 rs7524467 chr1:76194054 C/G cg03433033 chr1:76189801 ACADM 0.82 9.66 0.66 8.48e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg10108389 chr3:44770937 ZNF501 -0.46 -4.57 -0.38 1.16e-5 Depressive symptoms; TGCT cis rs2153535 0.580 rs6937186 chr6:8494493 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs12908161 1.000 rs56864281 chr15:85357649 C/A cg12863693 chr15:85201151 NMB 0.42 5.01 0.41 1.81e-6 Schizophrenia; TGCT cis rs11098499 0.909 rs28714195 chr4:120316950 A/T cg09307838 chr4:120376055 NA 0.68 6.7 0.52 6.46e-10 Corneal astigmatism; TGCT cis rs1403694 0.515 rs5030058 chr3:186452415 T/G cg12454167 chr3:186435060 KNG1 0.44 6.91 0.53 2.24e-10 Blood protein levels; TGCT cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg09177884 chr7:1199841 ZFAND2A -0.49 -4.64 -0.38 8.8e-6 Longevity;Endometriosis; TGCT cis rs832540 1.000 rs832540 chr5:56199202 G/A cg12311346 chr5:56204834 C5orf35 -0.49 -5.31 -0.43 4.89e-7 Coronary artery disease; TGCT cis rs2243480 1.000 rs778679 chr7:65840911 A/G cg20637647 chr7:64974828 NA 0.92 5.09 0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs4665809 0.590 rs10495756 chr2:26485586 A/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs6993244 1 rs6993244 chr8:8863059 C/G cg15556689 chr8:8085844 FLJ10661 0.75 6.75 0.52 5.16e-10 Mean corpuscular hemoglobin; TGCT trans rs459571 1.000 rs456207 chr9:136911140 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.75 -8.02 -0.58 6.93e-13 Platelet distribution width; TGCT cis rs8177253 0.931 rs8177256 chr3:133480276 G/T cg08439880 chr3:133502540 NA -0.31 -5.91 -0.47 3.08e-8 Iron status biomarkers; TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg01411255 chr17:61851458 DDX42;CCDC47 0.74 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs1799949 0.965 rs799908 chr17:41278916 A/G cg10047753 chr17:41438598 NA 0.77 7.29 0.55 3.18e-11 Menopause (age at onset); TGCT cis rs568617 0.953 rs658524 chr11:65647260 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.57 -5.22 -0.42 7.39e-7 Crohn's disease; TGCT cis rs10504229 0.683 rs55660024 chr8:58128943 G/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs11690935 0.527 rs7586556 chr2:172901887 G/C cg13550731 chr2:172543902 DYNC1I2 0.64 5.83 0.46 4.45e-8 Schizophrenia; TGCT cis rs854765 0.647 rs2955366 chr17:18024013 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.57 0.56 7.33e-12 Total body bone mineral density; TGCT cis rs2486288 0.656 rs11637838 chr15:45550657 A/G cg26924012 chr15:45694286 SPATA5L1 -0.75 -7.78 -0.57 2.39e-12 Glomerular filtration rate; TGCT cis rs892961 0.932 rs55661113 chr17:75408386 A/C cg05865280 chr17:75406074 SEPT9 0.29 7.02 0.53 1.26e-10 Airflow obstruction; TGCT cis rs6735179 0.565 rs6726887 chr2:1749257 A/G cg08534653 chr2:1747700 PXDN 0.54 4.45 0.37 1.92e-5 Response to antipsychotic treatment; TGCT cis rs28785552 0.796 rs8112908 chr19:53248041 C/T cg22067481 chr19:53234126 ZNF611 -0.4 -5.81 -0.46 4.95e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs909674 0.690 rs5750823 chr22:39829973 C/T cg05872129 chr22:39784769 NA -0.99 -9.57 -0.65 1.36e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg21226059 chr5:178986404 RUFY1 0.62 7.13 0.54 7.36e-11 Lung cancer; TGCT cis rs6733011 0.508 rs12712041 chr2:99522059 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.44 -0.44 2.74e-7 Bipolar disorder; TGCT cis rs10504229 0.679 rs17804870 chr8:58158071 A/G cg21724239 chr8:58056113 NA 0.43 4.44 0.37 1.93e-5 Developmental language disorder (linguistic errors); TGCT cis rs13256369 1.000 rs883648 chr8:8569521 A/G cg18904891 chr8:8559673 CLDN23 0.59 5.54 0.45 1.73e-7 Obesity-related traits; TGCT cis rs6089829 0.962 rs3746749 chr20:61667333 T/C cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467773 1.000 rs4713008 chr6:26538268 T/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs7524258 0.835 rs2412150 chr1:7303343 A/C cg07173049 chr1:7289937 CAMTA1 0.29 4.82 0.4 4.2e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs6867032 1.000 rs10462750 chr5:2012963 A/G cg26168224 chr5:2018326 NA 0.45 8.03 0.58 6.44e-13 Gut microbiome composition (winter); TGCT cis rs2067615 0.579 rs12424114 chr12:107144328 A/G cg15890332 chr12:107067104 RFX4 0.29 5.63 0.45 1.14e-7 Heart rate; TGCT cis rs1008375 0.897 rs67455495 chr4:17665238 A/T cg16339924 chr4:17578868 LAP3 -0.62 -5.0 -0.41 1.91e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12971120 0.838 rs2241510 chr18:72180739 G/A cg25817165 chr18:72167213 CNDP2 -0.26 -4.58 -0.38 1.12e-5 Refractive error; TGCT cis rs6671200 1.000 rs35179427 chr1:95670888 G/A cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs644799 0.932 rs480079 chr11:95643777 A/T cg03916912 chr11:95522834 CEP57;FAM76B -0.77 -9.57 -0.65 1.4e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2777491 1.000 rs1757455 chr15:41761332 G/T cg18705301 chr15:41695430 NDUFAF1 -0.76 -11.32 -0.71 7.77e-21 Ulcerative colitis; TGCT cis rs1005277 0.540 rs2474598 chr10:38430296 C/T cg13531842 chr10:38383804 ZNF37A 0.39 4.53 0.38 1.39e-5 Extrinsic epigenetic age acceleration; TGCT cis rs28374715 0.510 rs8034073 chr15:41545613 A/C cg18705301 chr15:41695430 NDUFAF1 -0.69 -8.88 -0.62 6.37e-15 Ulcerative colitis; TGCT cis rs2836974 0.966 rs7283516 chr21:40690537 A/G cg06238570 chr21:40685208 BRWD1 0.7 6.11 0.48 1.2e-8 Cognitive function; TGCT cis rs12765878 1.000 rs11191846 chr10:105649813 A/G cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs713587 0.776 rs1172294 chr2:25169200 A/G cg15423357 chr2:25149977 NA 0.59 5.98 0.47 2.17e-8 Body mass index in non-asthmatics; TGCT cis rs986417 0.748 rs8019541 chr14:60929145 A/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs3741151 1.000 rs74346863 chr11:73054772 C/T cg17517138 chr11:73019481 ARHGEF17 1.06 5.6 0.45 1.3e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg03236948 chr11:63997492 DNAJC4 0.38 4.71 0.39 6.48e-6 Platelet count; TGCT cis rs1008375 0.932 rs4698626 chr4:17605821 G/C cg16339924 chr4:17578868 LAP3 0.64 5.22 0.42 7.4e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs57221529 0.713 rs12522724 chr5:590742 T/C cg11887960 chr12:57824829 NA 1.17 9.7 0.66 6.57e-17 Lung disease severity in cystic fibrosis; TGCT cis rs1215050 0.716 rs11940331 chr4:99054041 G/C cg05340658 chr4:99064831 C4orf37 0.43 5.27 0.43 5.73e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg22920501 chr2:26401640 FAM59B -0.84 -6.85 -0.52 3.02e-10 Gut microbiome composition (summer); TGCT cis rs10782582 0.609 rs112431348 chr1:76275571 A/G cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs736408 0.609 rs1029871 chr3:52797634 G/C cg07507251 chr3:52567010 NT5DC2 0.48 6.67 0.51 7.55e-10 Bipolar disorder; TGCT cis rs1691799 0.899 rs903590 chr12:66745777 C/G cg16791601 chr12:66731901 HELB -0.27 -5.8 -0.46 5.11e-8 White blood cell count (basophil); TGCT cis rs10484885 0.824 rs72919976 chr6:90526686 C/G cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7829975 0.606 rs6422352 chr8:8794193 A/G cg06636001 chr8:8085503 FLJ10661 -0.73 -6.47 -0.5 2.01e-9 Mood instability; TGCT cis rs3858526 0.959 rs4758219 chr11:5951846 G/C cg13902645 chr11:5959945 NA -0.48 -5.0 -0.41 1.95e-6 DNA methylation (variation); TGCT cis rs7027203 1.000 rs7027203 chr9:96562563 A/C cg14396892 chr9:96623032 NA 0.24 4.81 0.4 4.27e-6 DNA methylation (variation); TGCT cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs10510102 0.872 rs12248806 chr10:123718153 T/C cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs910187 0.678 rs6122563 chr20:45813885 C/T cg27589058 chr20:45804311 EYA2 -0.35 -7.74 -0.57 3.01e-12 Migraine; TGCT cis rs7666738 0.830 rs7661264 chr4:98961574 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7100689 0.725 rs10736340 chr10:82061071 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.9 0.58 1.29e-12 Post bronchodilator FEV1; TGCT cis rs17376456 0.877 rs10063045 chr5:93457584 A/T cg25358565 chr5:93447407 FAM172A 0.91 7.62 0.56 5.75e-12 Diabetic retinopathy; TGCT cis rs7513165 0.551 rs57406581 chr1:204141832 C/T cg12731349 chr1:204159619 KISS1 0.49 4.84 0.4 3.74e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs6840360 0.615 rs12641433 chr4:152607548 A/C cg22705602 chr4:152727874 NA -0.33 -5.42 -0.44 2.93e-7 Intelligence (multi-trait analysis); TGCT cis rs904251 0.523 rs1776454 chr6:37482099 C/T cg25019722 chr6:37503610 NA -0.53 -8.19 -0.59 2.75e-13 Cognitive performance; TGCT cis rs4072705 0.646 rs10120967 chr9:127244134 C/T cg13476313 chr9:127244764 NR5A1 0.29 4.86 0.4 3.4e-6 Menarche (age at onset); TGCT cis rs7829975 0.511 rs1401390 chr8:8136410 C/T cg06636001 chr8:8085503 FLJ10661 0.73 6.46 0.5 2.18e-9 Mood instability; TGCT cis rs174479 0.677 rs174456 chr11:61656182 G/T cg01500311 chr11:61656094 FADS3 0.29 5.19 0.42 8.31e-7 Sphingolipid levels; TGCT cis rs75686122 0.892 rs17806104 chr8:104535511 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7829975 0.523 rs9644774 chr8:8559832 G/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.18 -0.42 8.67e-7 Mood instability; TGCT cis rs6912958 0.781 rs6940150 chr6:88287114 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs3806843 0.576 rs155363 chr5:140301543 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.44 -5.45 -0.44 2.65e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs2786098 0.577 rs12043482 chr1:197817740 T/C cg00114966 chr1:197893920 LHX9 0.38 4.59 0.38 1.05e-5 Asthma; TGCT trans rs7618501 0.735 rs9876508 chr3:49780844 G/A cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs7959452 0.590 rs11177643 chr12:69785712 T/G cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg03264133 chr6:25882463 NA -0.57 -5.28 -0.43 5.51e-7 Intelligence (multi-trait analysis); TGCT trans rs4824093 0.535 rs73443931 chr22:50291603 G/A cg09872104 chr7:134855509 C7orf49 -0.96 -7.87 -0.58 1.49e-12 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs4839827 1 rs4839827 chr6:96853967 C/T cg06623918 chr6:96969491 KIAA0776 0.65 6.72 0.52 5.89e-10 Migraine; TGCT cis rs6951245 0.938 rs11764937 chr7:1092074 C/T cg03188948 chr7:1209495 NA 0.53 4.47 0.37 1.72e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs72781680 0.898 rs56216411 chr2:23934533 G/A cg08917208 chr2:24149416 ATAD2B 0.89 5.41 0.44 3.11e-7 Lymphocyte counts; TGCT cis rs9951602 0.651 rs2959408 chr18:76681702 T/C cg00806245 chr18:76673096 NA 0.31 4.47 0.37 1.72e-5 Obesity-related traits; TGCT cis rs6964587 1.000 rs2106171 chr7:91750450 A/G cg17063962 chr7:91808500 NA 0.88 9.42 0.65 3.2e-16 Breast cancer; TGCT cis rs7267979 1.000 rs1888997 chr20:25298988 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7662987 0.517 rs2602880 chr4:100040653 C/T cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg18230493 chr5:56204884 C5orf35 -0.83 -6.54 -0.51 1.47e-9 Initial pursuit acceleration; TGCT cis rs3784262 0.669 rs12915821 chr15:58315685 A/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.27 -0.49 5.58e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7072216 0.763 rs10748730 chr10:100171440 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs6430585 0.646 rs1057031 chr2:136633962 G/A cg07169764 chr2:136633963 MCM6 1.26 12.74 0.75 2.78e-24 Corneal structure; TGCT cis rs2242116 0.932 rs4683301 chr3:46931478 A/T cg23352942 chr3:46931381 PTH1R 0.36 5.86 0.47 3.84e-8 Birth weight; TGCT cis rs6088580 0.634 rs6059829 chr20:33017074 G/A cg06115741 chr20:33292138 TP53INP2 0.55 4.81 0.4 4.24e-6 Glomerular filtration rate (creatinine); TGCT cis rs950027 0.572 rs12910764 chr15:45609360 T/C cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.44 -0.56 1.48e-11 Response to fenofibrate (adiponectin levels); TGCT cis rs7147624 0.938 rs7147231 chr14:66212371 A/G cg03016385 chr14:66212404 NA -0.52 -7.29 -0.55 3.26e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2404602 0.716 rs7174953 chr15:76906847 A/C cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.07e-6 Blood metabolite levels; TGCT cis rs1005277 0.502 rs2800484 chr10:38542415 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6089829 0.926 rs6062395 chr20:61667904 A/G cg02380750 chr20:61661411 NA 0.34 6.09 0.48 1.29e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs6831352 1.000 rs6822348 chr4:100053894 A/T cg12011299 chr4:100065546 ADH4 0.41 5.16 0.42 9.55e-7 Alcohol dependence; TGCT cis rs7178424 0.875 rs17271193 chr15:62165168 A/G cg00456672 chr15:62358751 C2CD4A -0.31 -4.69 -0.39 7.14e-6 Height; TGCT cis rs9790314 0.905 rs1154701 chr3:161008025 T/A cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs10832963 0.961 rs10832954 chr11:18643559 G/A cg20219074 chr11:18656078 SPTY2D1 0.97 9.61 0.65 1.12e-16 Breast cancer; TGCT cis rs79387448 0.745 rs72995626 chr2:103162580 T/C cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs7586879 0.638 rs10203482 chr2:25136916 T/C cg01884057 chr2:25150051 NA 0.34 6.58 0.51 1.16e-9 Body mass index; TGCT cis rs9393777 0.513 rs9379895 chr6:26592707 A/G cg15659132 chr6:26577336 NA -0.65 -4.84 -0.4 3.82e-6 Intelligence (multi-trait analysis); TGCT cis rs35883536 0.626 rs80052576 chr1:101039229 A/G cg06223162 chr1:101003688 GPR88 -0.42 -8.0 -0.58 7.38e-13 Monocyte count; TGCT cis rs7586879 1.000 rs7603153 chr2:25116966 T/C cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs9796 0.689 rs576336 chr15:41452771 C/T cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.97 -0.53 1.68e-10 Menopause (age at onset); TGCT cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg22105103 chr4:187893119 NA 0.33 4.54 0.38 1.3e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs7684646 chr4:99071062 C/T cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.42 1.33e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2749592 0.725 rs9417245 chr10:37826322 C/T cg25427524 chr10:38739819 LOC399744 0.34 5.01 0.41 1.86e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs12971120 0.891 rs2303463 chr18:72168608 G/A cg25817165 chr18:72167213 CNDP2 -0.29 -4.98 -0.41 2.05e-6 Refractive error; TGCT cis rs9611565 0.592 rs5758406 chr22:42076641 A/G cg06481639 chr22:41940642 POLR3H 0.73 6.62 0.51 9.76e-10 Vitiligo; TGCT cis rs10465746 0.935 rs942848 chr1:84427707 G/C cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs7843479 1.000 rs2306641 chr8:21833965 A/G cg17168535 chr8:21777572 XPO7 -0.68 -6.39 -0.5 3.01e-9 Mean corpuscular volume; TGCT cis rs1552244 0.572 rs67227131 chr3:10172744 G/A cg00149659 chr3:10157352 C3orf10 1.22 7.58 0.56 7.14e-12 Alzheimer's disease; TGCT trans rs4650994 0.524 rs2761465 chr1:178579404 G/T cg05059571 chr16:84539110 KIAA1609 0.52 10.34 0.68 1.85e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4073582 1.000 rs4073582 chr11:66050712 G/A cg16950941 chr11:66035639 RAB1B 0.53 4.44 0.37 1.96e-5 Gout; TGCT cis rs877282 1.000 rs877282 chr10:771532 G/A cg17470449 chr10:769945 NA 0.31 4.77 0.39 5.04e-6 Uric acid levels; TGCT cis rs908922 0.676 rs7532535 chr1:152517597 T/A cg20991723 chr1:152506922 NA 0.46 6.17 0.48 8.79e-9 Hair morphology; TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg03760483 chr17:6899297 ALOX12 -0.44 -5.2 -0.42 7.81e-7 Tonsillectomy; TGCT cis rs8180040 1.000 rs2302278 chr3:47361082 G/T cg27129171 chr3:47204927 SETD2 -0.68 -8.58 -0.61 3.19e-14 Colorectal cancer; TGCT cis rs941873 0.869 rs7917610 chr10:81117237 T/C cg09469691 chr10:81107165 PPIF 0.64 6.53 0.51 1.5e-9 Height; TGCT cis rs151997 0.962 rs152687 chr5:50208563 A/G cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs736408 0.716 rs2300149 chr3:52822921 C/T cg07507251 chr3:52567010 NT5DC2 0.46 6.48 0.5 1.95e-9 Bipolar disorder; TGCT trans rs3780486 0.846 rs10124479 chr9:33136233 T/G cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT cis rs1497406 1.000 rs1497406 chr1:16505320 A/G cg20430773 chr1:16534157 ARHGEF19 0.43 4.74 0.39 5.71e-6 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs903263 0.813 rs10874429 chr1:84591649 T/C cg09664975 chr1:84543551 PRKACB 0.49 4.55 0.38 1.27e-5 Breast cancer (male); TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg02073558 chr3:44770973 ZNF501 0.61 5.87 0.47 3.78e-8 Depressive symptoms; TGCT cis rs10114408 0.959 rs7852957 chr9:96647881 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7267979 0.586 rs1473695 chr20:25186965 A/G cg16686733 chr20:25566563 NINL 0.53 5.41 0.44 3.06e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11190604 0.943 rs2495744 chr10:102329409 C/T cg23241863 chr10:102295624 HIF1AN 0.64 4.78 0.39 4.95e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg22535103 chr8:58192502 C8orf71 -0.46 -5.13 -0.42 1.09e-6 Developmental language disorder (linguistic errors); TGCT cis rs11190604 0.697 rs12355942 chr10:102201320 T/C cg23241863 chr10:102295624 HIF1AN -0.65 -5.05 -0.41 1.53e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6484504 0.516 rs1999250 chr11:31287455 C/T cg26647111 chr11:31128758 NA -0.34 -4.69 -0.39 7.02e-6 Red blood cell count; TGCT cis rs826838 0.935 rs980571 chr12:39127532 C/G cg26384229 chr12:38710491 ALG10B -0.87 -7.98 -0.58 8.39e-13 Heart rate; TGCT cis rs868036 0.718 rs28587941 chr15:68122509 T/C cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs7085104 0.572 rs284860 chr10:104572963 T/C cg05855489 chr10:104503620 C10orf26 -0.63 -6.21 -0.49 7.3e-9 Immature fraction of reticulocytes;Schizophrenia; TGCT trans rs10435719 0.702 rs77055881 chr8:11790581 T/C cg15556689 chr8:8085844 FLJ10661 0.76 7.18 0.54 5.62e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs28374715 0.580 rs8030228 chr15:41636867 A/G cg18705301 chr15:41695430 NDUFAF1 -0.91 -14.89 -0.8 2.14e-29 Ulcerative colitis; TGCT cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg03060546 chr3:49711283 APEH 0.51 4.91 0.4 2.8e-6 Menarche (age at onset); TGCT trans rs7618501 0.521 rs55692411 chr3:49911155 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.85 8.84 0.62 7.83e-15 Intelligence (multi-trait analysis); TGCT cis rs6893807 0.667 rs7733438 chr5:87986284 T/G cg24804195 chr5:87968844 LOC645323 0.73 4.9 0.4 2.94e-6 Body mass index; TGCT cis rs6095298 0.595 rs7267607 chr20:47447870 A/C cg12307787 chr20:48099359 KCNB1 0.44 4.67 0.39 7.75e-6 Intelligence (multi-trait analysis); TGCT cis rs7605378 0.752 rs769960 chr2:200710706 G/T cg17644776 chr2:200775616 C2orf69 -0.34 -7.08 -0.54 9.64e-11 Osteoporosis; TGCT cis rs7666738 0.830 rs7664169 chr4:99037859 C/T cg17366294 chr4:99064904 C4orf37 -0.71 -7.28 -0.55 3.38e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs644799 0.965 rs534488 chr11:95562327 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg25151919 chr3:44754333 ZNF502 -0.47 -5.45 -0.44 2.56e-7 Depressive symptoms; TGCT cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1669338 0.588 rs3804783 chr3:3184442 C/T cg16797762 chr3:3221439 CRBN -0.83 -5.24 -0.43 6.58e-7 White matter integrity; TGCT cis rs9796 0.689 rs28409432 chr15:41447454 G/A cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.83 -0.52 3.38e-10 Menopause (age at onset); TGCT cis rs854765 0.927 rs12943914 chr17:17980671 A/G cg09796270 chr17:17721594 SREBF1 0.26 5.05 0.41 1.54e-6 Total body bone mineral density; TGCT cis rs453301 0.686 rs28665409 chr8:8869277 G/A cg15556689 chr8:8085844 FLJ10661 -0.61 -4.98 -0.41 2.09e-6 Joint mobility (Beighton score); TGCT cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg01448562 chr3:133502909 NA -0.36 -7.37 -0.55 2.11e-11 Iron status biomarkers; TGCT cis rs727505 1.000 rs7791430 chr7:124429953 G/T cg23710748 chr7:124431027 NA -0.26 -4.56 -0.38 1.21e-5 Lewy body disease; TGCT cis rs10193935 0.901 rs13384885 chr2:42536646 G/C cg27598129 chr2:42591480 NA -0.4 -5.56 -0.45 1.57e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg27286337 chr10:134555280 INPP5A -0.38 -5.09 -0.42 1.3e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs11098499 0.909 rs9759478 chr4:120367998 G/A cg09307838 chr4:120376055 NA 0.68 6.52 0.51 1.59e-9 Corneal astigmatism; TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg17054783 chr10:134559939 INPP5A 0.26 4.92 0.4 2.68e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4788570 0.615 rs2032918 chr16:71703436 T/G cg06353428 chr16:71660113 MARVELD3 1.56 12.54 0.75 8.54e-24 Intelligence (multi-trait analysis); TGCT cis rs16854884 0.837 rs6804060 chr3:143804040 C/T cg06585982 chr3:143692056 C3orf58 0.63 4.72 0.39 6.18e-6 Economic and political preferences (feminism/equality); TGCT cis rs16867321 0.950 rs4667223 chr2:181498302 C/G cg23363182 chr2:181467187 NA -0.38 -5.55 -0.45 1.62e-7 Obesity; TGCT cis rs7267979 1.000 rs2500446 chr20:25339664 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3733585 0.588 rs6449154 chr4:9956404 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7681440 0.626 rs1372510 chr4:90817259 G/A cg20003494 chr4:90757398 SNCA -0.54 -4.88 -0.4 3.21e-6 Dementia with Lewy bodies; TGCT trans rs11722228 1.000 rs4697695 chr4:9915850 C/T cg26043149 chr18:55253948 FECH 0.76 7.26 0.55 3.68e-11 Gout;Urate levels;Serum uric acid levels; TGCT cis rs57994353 0.568 rs1130635 chr9:139317869 A/G cg13741927 chr9:139327495 INPP5E -0.24 -5.47 -0.44 2.42e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs3008870 0.755 rs4655661 chr1:67408828 A/C cg08660285 chr1:67390436 MIER1;WDR78 0.79 8.41 0.6 8.39e-14 Lymphocyte percentage of white cells; TGCT cis rs60843830 1.000 rs60843830 chr2:286756 C/G cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.54 0.51 1.42e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.4 -4.76 -0.39 5.24e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg04234412 chr22:24373322 LOC391322 0.9 10.66 0.69 3.1400000000000002e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3803170 0.513 rs11065888 chr12:111828663 G/C cg10833066 chr12:111807467 FAM109A 0.36 5.41 0.44 3.09e-7 Mean corpuscular hemoglobin; TGCT cis rs3771570 1.000 rs16843590 chr2:242298228 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs2836633 0.929 rs62217517 chr21:40033177 T/A cg05519781 chr21:40033154 ERG 0.7 6.95 0.53 1.86e-10 Coronary artery disease; TGCT cis rs7617773 0.746 rs4130995 chr3:48358255 C/T cg11946769 chr3:48343235 NME6 0.75 6.94 0.53 1.92e-10 Coronary artery disease; TGCT cis rs9341808 0.718 rs3805922 chr6:80891989 A/G cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs28595532 0.920 rs115090549 chr4:119753554 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7772486 0.875 rs2814871 chr6:146312274 G/T cg23711669 chr6:146136114 FBXO30 0.84 8.85 0.62 7.33e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1218582 0.772 rs2174507 chr1:154887949 C/T cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs12220238 0.841 rs11000993 chr10:76084111 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.87 6.44 0.5 2.37e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1552244 0.572 rs59074548 chr3:10164347 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs6500602 0.682 rs3761679 chr16:4457907 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.24 0.49 6.25e-9 Schizophrenia; TGCT cis rs13256369 0.851 rs11249890 chr8:8565245 G/T cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs2243480 1.000 rs316329 chr7:65608416 A/C cg07424592 chr7:64974309 NA 1.31 7.66 0.57 4.63e-12 Diabetic kidney disease; TGCT cis rs73198271 0.628 rs11783457 chr8:8588842 G/C ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs11578119 0.898 rs11577004 chr1:170440622 C/T cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs6964587 1.000 rs7811564 chr7:91663364 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT trans rs7698623 0.702 rs1599722 chr4:88782786 A/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs7586879 0.609 rs7608976 chr2:25075281 G/A cg01884057 chr2:25150051 NA 0.31 5.75 0.46 6.47e-8 Body mass index; TGCT cis rs3008870 0.920 rs2755253 chr1:67470843 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.01 10.3 0.68 2.3e-18 Lymphocyte percentage of white cells; TGCT trans rs459571 0.920 rs433402 chr9:136898627 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.71 -7.72 -0.57 3.39e-12 Platelet distribution width; TGCT cis rs1552244 1.000 rs111392584 chr3:10075991 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs4409675 0.576 rs6679432 chr1:28227665 T/C cg23691781 chr1:28212827 C1orf38 0.26 5.44 0.44 2.76e-7 Corneal astigmatism; TGCT cis rs6433857 0.536 rs7557023 chr2:181350474 G/A cg23363182 chr2:181467187 NA -0.32 -4.85 -0.4 3.59e-6 Body mass index; TGCT cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg12386194 chr3:101231763 SENP7 0.61 5.75 0.46 6.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs80282103 0.618 rs56004802 chr10:1159187 C/T cg08668510 chr10:1095578 IDI1 1.08 5.04 0.41 1.64e-6 Glomerular filtration rate (creatinine); TGCT cis rs6684514 1.000 rs10908502 chr1:156300082 A/G cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4665809 1.000 rs4233710 chr2:26291565 G/A cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs6438424 0.502 rs6792076 chr3:117724113 A/G cg15509235 chr3:117715573 NA 0.54 5.41 0.44 3.16e-7 Menarche (age at onset); TGCT cis rs854765 0.547 rs7212167 chr17:17913504 G/A cg04398451 chr17:18023971 MYO15A -0.32 -5.12 -0.42 1.15e-6 Total body bone mineral density; TGCT cis rs12142240 0.698 rs41294476 chr1:46818374 C/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs17152411 0.895 rs11245418 chr10:126586319 T/C cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs13242816 1.000 rs55977427 chr7:116110768 C/T cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs12530845 1.000 rs56060450 chr7:135331777 C/T cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs4919669 0.668 rs7094614 chr10:104334874 G/C cg05855489 chr10:104503620 C10orf26 0.71 4.69 0.39 7.18e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs9372253 1.000 rs11153232 chr6:110716252 G/T cg01119278 chr6:110721349 DDO 0.35 5.68 0.45 9e-8 Platelet distribution width; TGCT cis rs11031096 0.678 rs2044135 chr11:4187233 G/A cg18678763 chr11:4115507 RRM1 -0.46 -5.95 -0.47 2.5e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs889312 0.500 rs3099460 chr5:56133748 G/C cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs2486288 0.656 rs12910009 chr15:45572408 A/G cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.38 -0.44 3.57e-7 Glomerular filtration rate; TGCT cis rs769267 0.965 rs2074303 chr19:19381755 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs9486719 1.000 rs2142652 chr6:96868504 A/C cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs2762353 0.574 rs4409177 chr6:25694491 T/G cg12310025 chr6:25882481 NA 0.94 9.45 0.65 2.65e-16 Blood metabolite levels; TGCT cis rs7208859 0.510 rs216402 chr17:28917126 A/T cg13385521 chr17:29058706 SUZ12P 0.86 5.12 0.42 1.15e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs6570726 0.935 rs447818 chr6:145868996 C/T cg05347473 chr6:146136440 FBXO30 0.49 4.51 0.38 1.46e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs763014 0.966 rs4984677 chr16:671682 A/G cg07343612 chr16:622815 PIGQ -0.42 -8.4 -0.6 8.58e-14 Height; TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg10263370 chr3:44754102 ZNF502 -0.44 -5.19 -0.42 8.19e-7 Depressive symptoms; TGCT trans rs2832077 0.527 rs11088095 chr21:30223188 A/T cg14791747 chr16:20752902 THUMPD1 1.09 12.67 0.75 4.09e-24 Cognitive test performance; TGCT cis rs4711350 0.749 rs7752348 chr6:33718252 C/G cg13859433 chr6:33739653 LEMD2 -0.31 -4.55 -0.38 1.24e-5 Schizophrenia; TGCT cis rs7666738 0.830 rs2865980 chr4:99027422 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2469997 1.000 rs2447174 chr8:120358571 G/A cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs9682041 0.696 rs11917147 chr3:170088448 C/T cg11886554 chr3:170076028 SKIL 0.6 4.76 0.39 5.35e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs941408 0.515 rs1005556 chr19:2778543 G/T cg06609049 chr19:2785107 THOP1 1.12 13.05 0.76 5.1e-25 Total cholesterol levels; TGCT cis rs6840360 0.593 rs10013612 chr4:152693622 A/G cg17479576 chr4:152424074 FAM160A1 -0.53 -5.26 -0.43 5.99e-7 Intelligence (multi-trait analysis); TGCT cis rs929354 0.772 rs3802117 chr7:156987000 C/T cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT trans rs6089829 0.962 rs6062393 chr20:61663230 G/A cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs7786808 0.588 rs4909078 chr7:158183835 C/G cg01191920 chr7:158217561 PTPRN2 -0.36 -5.27 -0.43 5.82e-7 Obesity-related traits; TGCT cis rs950169 0.579 rs12913054 chr15:84664456 A/G cg11189052 chr15:85197271 WDR73 0.65 5.06 0.41 1.45e-6 Schizophrenia; TGCT cis rs7178572 0.625 rs907372 chr15:77844516 G/T cg22256960 chr15:77711686 NA -0.79 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs12908161 1.000 rs12899981 chr15:85302373 G/A cg17173187 chr15:85201210 NMB 0.57 6.41 0.5 2.81e-9 Schizophrenia; TGCT cis rs7833790 1.000 rs1463259 chr8:82737745 A/G cg27398817 chr8:82754497 SNX16 -0.87 -6.35 -0.5 3.66e-9 Diastolic blood pressure; TGCT cis rs4595586 0.545 rs6580893 chr12:39371885 G/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs3849570 0.643 rs6797240 chr3:81971856 T/C cg07356753 chr3:81810745 GBE1 -0.64 -5.62 -0.45 1.19e-7 Waist circumference;Body mass index; TGCT cis rs9788682 1.000 rs7163730 chr15:78814681 A/G cg06917634 chr15:78832804 PSMA4 -0.71 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs1990950 0.692 rs7723675 chr5:156830865 A/G cg25387487 chr5:157003181 ADAM19 0.3 4.66 0.39 7.98e-6 Lung function (FEV1/FVC); TGCT cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.07 13.43 0.77 6.22e-26 Height; TGCT cis rs2243480 0.615 rs34363376 chr7:65939536 T/C cg18252515 chr7:66147081 NA -1.18 -7.56 -0.56 7.99e-12 Diabetic kidney disease; TGCT cis rs7249142 0.597 rs7250650 chr19:19285989 A/T cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.55 0.45 1.64e-7 IgG glycosylation; TGCT cis rs7264396 0.747 rs2425158 chr20:34419664 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -4.89 -0.4 3.06e-6 Total cholesterol levels; TGCT cis rs1862618 0.671 rs2255726 chr5:56243128 T/C cg12311346 chr5:56204834 C5orf35 0.55 5.89 0.47 3.44e-8 Initial pursuit acceleration; TGCT cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg03806693 chr22:41940476 POLR3H -1.08 -11.99 -0.73 1.84e-22 Vitiligo; TGCT cis rs2191566 0.821 rs59756444 chr19:44513656 C/G cg03039196 chr19:44506973 ZNF230 0.54 4.67 0.39 7.62e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs9929218 0.551 rs2296409 chr16:68713730 G/A cg01251360 chr16:68772225 CDH1 -0.26 -4.69 -0.39 6.99e-6 Colorectal cancer; TGCT cis rs17826219 0.706 rs2322197 chr17:29105805 T/C cg13385521 chr17:29058706 SUZ12P 0.78 4.72 0.39 6.2e-6 Body mass index; TGCT cis rs7914558 1.000 rs7911789 chr10:104756374 T/C cg15744005 chr10:104629667 AS3MT -0.4 -4.89 -0.4 3.06e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4808199 1.000 rs60321073 chr19:19499598 A/G cg03709012 chr19:19516395 GATAD2A 0.99 7.7 0.57 3.74e-12 Nonalcoholic fatty liver disease; TGCT cis rs2072499 0.865 rs2758608 chr1:156202860 A/T cg24450063 chr1:156163899 SLC25A44 1.05 11.04 0.7 3.74e-20 Testicular germ cell tumor; TGCT cis rs7584330 0.554 rs2325838 chr2:238386515 C/A cg14458575 chr2:238380390 NA 0.58 5.05 0.41 1.53e-6 Prostate cancer; TGCT cis rs1552244 0.810 rs7612908 chr3:10089148 A/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs8177253 1.000 rs8177240 chr3:133477701 T/G cg16414030 chr3:133502952 NA -0.61 -9.4 -0.65 3.55e-16 Iron status biomarkers; TGCT cis rs245880 0.740 rs245898 chr7:29194143 G/A cg17163760 chr7:29186267 CPVL -0.41 -5.08 -0.42 1.35e-6 Warfarin maintenance dose; TGCT cis rs1005277 0.579 rs1740735 chr10:38497777 A/C cg25427524 chr10:38739819 LOC399744 -0.38 -8.01 -0.58 6.99e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9926296 0.546 rs7187436 chr16:89845110 A/T cg04287289 chr16:89883240 FANCA 0.93 11.53 0.72 2.36e-21 Vitiligo; TGCT cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg00684032 chr4:1343700 KIAA1530 0.23 5.01 0.41 1.79e-6 Obesity-related traits; TGCT cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs1577917 0.771 rs9362237 chr6:86409064 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 5.58 0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs155076 1.000 rs195570 chr13:21867580 T/G cg14456004 chr13:21872349 NA -1.17 -10.03 -0.67 1.09e-17 White matter hyperintensity burden; TGCT cis rs7044106 0.762 rs10760107 chr9:123383630 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.58 6.37 0.5 3.32e-9 Hip circumference adjusted for BMI; TGCT cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg20607798 chr8:58055168 NA 0.62 5.19 0.42 8.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs941408 0.515 rs1640265 chr19:2784405 C/T cg06609049 chr19:2785107 THOP1 1.14 13.14 0.76 2.97e-25 Total cholesterol levels; TGCT trans rs2801405 0.584 rs1596652 chr10:100644484 C/G cg04906546 chr1:208317836 PLXNA2 -0.29 -6.86 -0.52 2.94e-10 Obesity-related traits; TGCT cis rs2204008 0.743 rs2127952 chr12:37995364 G/T cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.56e-12 Bladder cancer; TGCT cis rs10510102 0.748 rs4589226 chr10:123710588 A/G cg23691251 chr10:123688108 ATE1 -0.6 -4.65 -0.39 8.51e-6 Breast cancer; TGCT cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.6 0.65 1.18e-16 Cognitive function; TGCT cis rs3733585 0.781 rs13103879 chr4:9972879 T/C cg11266682 chr4:10021025 SLC2A9 -0.62 -8.75 -0.62 1.28e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1008375 0.966 rs3733581 chr4:17695206 C/G cg18681998 chr4:17616180 MED28 -0.83 -7.63 -0.57 5.33e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11024102 1.000 rs11024102 chr11:17008605 T/C cg15378786 chr11:17036137 PLEKHA7 0.49 4.52 0.38 1.44e-5 Glaucoma (primary angle closure); TGCT cis rs2932538 0.922 rs6537744 chr1:113096746 C/G cg22162597 chr1:113214053 CAPZA1 0.27 5.89 0.47 3.46e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs3780378 0.875 rs7861599 chr9:5067298 C/T cg02405213 chr9:5042618 JAK2 -0.64 -8.86 -0.62 7.1e-15 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs2241685 0.540 rs4853827 chr2:1867400 A/C cg21862353 chr2:1801628 MYT1L -0.47 -4.71 -0.39 6.64e-6 Attention deficit hyperactivity disorder; TGCT cis rs56104184 0.725 rs4347731 chr19:49385154 A/G cg15549821 chr19:49342101 PLEKHA4 -0.73 -8.89 -0.62 5.96e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs35146811 0.695 rs1618851 chr7:99810643 T/G cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs921968 0.612 rs573555 chr2:219348888 A/C cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs422249 0.512 rs174566 chr11:61592362 A/G cg01500311 chr11:61656094 FADS3 -0.3 -5.22 -0.42 7.4e-7 Trans fatty acid levels; TGCT cis rs367615 0.704 rs7705399 chr5:108850351 G/C cg17395555 chr5:108820864 NA 0.32 6.04 0.48 1.67e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg07424592 chr7:64974309 NA 1.32 8.15 0.59 3.39e-13 Diabetic kidney disease; TGCT cis rs7246657 0.941 rs7259618 chr19:37750719 G/A cg18154014 chr19:37997991 ZNF793 0.8 5.14 0.42 1.02e-6 Coronary artery calcification; TGCT cis rs3806843 0.576 rs246066 chr5:140323147 T/G cg07102913 chr5:140593443 PCDHB13 -0.48 -4.81 -0.4 4.26e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs637571 0.522 rs503524 chr11:65751764 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.68 6.72 0.52 5.84e-10 Eosinophil percentage of white cells; TGCT cis rs67311347 1.000 rs11716675 chr3:40485280 G/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg18538332 chr22:24372958 LOC391322 -0.77 -7.27 -0.55 3.57e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs12701220 0.894 rs2141274 chr7:1034717 G/A cg27454412 chr7:1067447 C7orf50 -0.5 -4.78 -0.39 4.9e-6 Bronchopulmonary dysplasia; TGCT cis rs10779751 0.734 rs2791649 chr1:11132561 A/G cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs1334894 0.901 rs56062505 chr6:35521182 G/A cg24281267 chr6:35479648 TULP1 -0.43 -4.54 -0.38 1.34e-5 Coronary artery disease; TGCT cis rs9486719 1.000 rs12208124 chr6:97027942 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs7312933 0.566 rs11181454 chr12:42746486 T/C cg19980929 chr12:42632907 YAF2 -0.41 -5.72 -0.46 7.37e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs5769707 0.967 rs8141807 chr22:50043738 C/G cg20744362 chr22:50050164 C22orf34 0.27 4.57 0.38 1.18e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg23221052 chr5:179740743 GFPT2 -0.36 -5.72 -0.46 7.59e-8 Height; TGCT cis rs9467773 1.000 rs6456734 chr6:26566965 G/T cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg08859206 chr1:53392774 SCP2 -0.49 -7.71 -0.57 3.61e-12 Monocyte count; TGCT cis rs3806843 0.576 rs246043 chr5:140330924 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs1814175 0.791 rs1722011 chr11:49899340 G/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.04 -0.53 1.16e-10 Height; TGCT cis rs2439831 0.867 rs2278860 chr15:43659046 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.97 -8.19 -0.59 2.78e-13 Lung cancer in ever smokers; TGCT cis rs950027 0.620 rs1346267 chr15:45690989 A/G cg14582100 chr15:45693742 SPATA5L1 0.44 5.49 0.44 2.21e-7 Response to fenofibrate (adiponectin levels); TGCT cis rs7980687 0.628 rs2102949 chr12:123676763 G/A cg00376283 chr12:123451042 ABCB9 0.79 6.75 0.52 5e-10 Height;Educational attainment;Head circumference (infant); TGCT cis rs644799 0.710 rs11021309 chr11:95501898 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.81 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7000551 0.653 rs4872504 chr8:22326717 A/G cg12081754 chr8:22256438 SLC39A14 0.28 4.64 0.38 8.8e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7044106 0.791 rs10984997 chr9:123481206 T/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.47 5.09 0.42 1.31e-6 Hip circumference adjusted for BMI; TGCT cis rs2692947 0.683 rs1813381 chr2:96422939 C/T cg23100626 chr2:96804247 ASTL -0.49 -5.92 -0.47 3e-8 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs1729951 0.575 rs835642 chr3:136703365 A/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs7249142 0.562 rs10418053 chr19:19287164 A/G cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.34 -4.5 -0.37 1.56e-5 IgG glycosylation; TGCT cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs28493229 0.522 rs17713068 chr19:41270055 A/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.58 5.1 0.42 1.25e-6 Kawasaki disease; TGCT cis rs35113840 1 rs35113840 chr2:239101656 G/GA cg17459225 chr2:239074497 NA 0.31 4.59 0.38 1.08e-5 Red cell distribution width; TGCT cis rs3796352 1.000 rs11713290 chr3:52971579 G/A cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs72781680 0.898 rs10490752 chr2:24025132 C/T cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs854765 0.583 rs8065416 chr17:17851162 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.85 0.58 1.65e-12 Total body bone mineral density; TGCT cis rs6582630 0.519 rs10880629 chr12:38533611 T/G cg26384229 chr12:38710491 ALG10B 0.86 7.8 0.57 2.22e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs477895 0.713 rs2282490 chr11:63962152 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 6.47 0.5 2.06e-9 Mean platelet volume; TGCT cis rs700651 0.675 rs2033570 chr2:198952637 C/T cg00792783 chr2:198669748 PLCL1 0.54 4.56 0.38 1.23e-5 Intracranial aneurysm; TGCT cis rs11671005 0.695 rs8106061 chr19:58917990 G/C cg26874164 chr19:58962979 ZNF324B 0.91 8.18 0.59 2.88e-13 Mean platelet volume; TGCT cis rs9814567 1.000 rs13089966 chr3:134279197 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs7586879 0.575 rs6706316 chr2:25128351 C/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs2637266 0.905 rs2130796 chr10:78329712 C/G cg18941641 chr10:78392320 NA 0.43 5.48 0.44 2.29e-7 Pulmonary function; TGCT cis rs6938 0.534 rs1130741 chr15:75189930 A/G cg10253484 chr15:75165896 SCAMP2 -0.55 -5.07 -0.41 1.43e-6 Breast cancer; TGCT cis rs13256369 0.951 rs13260947 chr8:8565883 A/G cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs595982 0.559 rs4802516 chr19:49366170 T/C cg17863274 chr19:49399704 TULP2 -0.47 -6.78 -0.52 4.43e-10 Red cell distribution width; TGCT cis rs2688608 0.592 rs10762560 chr10:75495405 T/G cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs28595532 0.920 rs115354352 chr4:119750358 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4906332 1.000 rs8012623 chr14:103937086 G/A cg26031613 chr14:104095156 KLC1 -0.52 -4.72 -0.39 6.31e-6 Coronary artery disease; TGCT cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg02503808 chr4:7069936 GRPEL1 0.98 9.23 0.64 9.22e-16 Monocyte percentage of white cells; TGCT cis rs11098499 0.954 rs10017371 chr4:120293776 A/G cg09307838 chr4:120376055 NA 0.62 5.97 0.47 2.35e-8 Corneal astigmatism; TGCT cis rs12615966 1.000 rs12620555 chr2:105379115 T/C cg16465502 chr2:105461796 NA 0.78 5.01 0.41 1.83e-6 Pancreatic cancer; TGCT cis rs9952991 0.709 rs755390 chr18:12763706 T/C cg23598886 chr18:12777645 NA -0.68 -4.74 -0.39 5.74e-6 Inflammatory skin disease; TGCT cis rs9640161 0.830 rs6722 chr7:150068933 T/C cg10018233 chr7:150070692 REPIN1 0.42 6.84 0.52 3.24e-10 Blood protein levels;Circulating chemerin levels; TGCT cis rs7727544 0.570 rs7701237 chr5:131534381 C/T cg24060327 chr5:131705240 SLC22A5 -0.44 -4.5 -0.37 1.56e-5 Blood metabolite levels; TGCT cis rs6663390 0.510 rs2300055 chr1:208065380 C/T cg03990033 chr1:208084030 CD34 0.64 4.46 0.37 1.81e-5 Facial morphology (factor 18); TGCT cis rs12681287 0.547 rs7465511 chr8:87521481 C/T cg27223183 chr8:87520930 FAM82B -0.96 -7.03 -0.53 1.21e-10 Caudate activity during reward; TGCT cis rs7909074 0.966 rs879074 chr10:45400053 G/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.35 -0.43 4.05e-7 Mean corpuscular volume; TGCT cis rs74054849 0.850 rs75348249 chr1:15961264 C/T cg05660106 chr1:15850417 CASP9 0.86 4.48 0.37 1.68e-5 Alcoholic chronic pancreatitis; TGCT cis rs8177253 0.965 rs8177260 chr3:133480458 T/A cg08439880 chr3:133502540 NA -0.32 -6.09 -0.48 1.33e-8 Iron status biomarkers; TGCT cis rs9811920 0.660 rs11719468 chr3:99671848 G/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.45 0.44 2.55e-7 Axial length; TGCT cis rs7523050 0.643 rs36052234 chr1:109402943 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs9814567 1.000 rs9832785 chr3:134213070 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs892961 0.932 rs12453822 chr17:75416792 G/A cg05865280 chr17:75406074 SEPT9 0.28 6.45 0.5 2.27e-9 Airflow obstruction; TGCT cis rs11264213 0.901 rs584873 chr1:36431806 C/A cg27506609 chr1:36549197 TEKT2 0.4 4.54 0.38 1.32e-5 Schizophrenia; TGCT cis rs939574 0.720 rs6714820 chr2:220071803 C/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.06 -6.52 -0.51 1.6e-9 Platelet distribution width; TGCT cis rs4713675 0.709 rs542441 chr6:33675851 A/C cg06471254 chr6:33690276 IP6K3 0.24 4.7 0.39 6.71e-6 Plateletcrit; TGCT cis rs769267 0.931 rs2965193 chr19:19454828 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs2153535 0.623 rs2327055 chr6:8443145 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs7829975 0.593 rs2921051 chr8:8320104 C/A cg15556689 chr8:8085844 FLJ10661 0.67 6.38 0.5 3.15e-9 Mood instability; TGCT trans rs12339966 0.581 rs11794337 chr9:11333155 C/T cg03488587 chr11:64876988 C11orf2 0.32 7.03 0.53 1.19e-10 Systolic blood pressure; TGCT cis rs853679 0.517 rs36078605 chr6:28078032 A/C cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs9486715 0.867 rs2499775 chr6:97007340 C/T cg06623918 chr6:96969491 KIAA0776 -1.1 -14.37 -0.79 3.55e-28 Headache; TGCT cis rs11096990 0.552 rs7655170 chr4:39173604 T/G cg24403649 chr4:39172243 NA 0.2 4.48 0.37 1.7e-5 Cognitive function; TGCT cis rs1008375 1.000 rs6819132 chr4:17689752 G/T cg18681998 chr4:17616180 MED28 -0.91 -8.98 -0.63 3.58e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg18305652 chr10:134549665 INPP5A 0.34 5.52 0.44 1.87e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7615952 0.673 rs7632557 chr3:125634881 G/C cg05084668 chr3:125655381 ALG1L -0.63 -4.64 -0.38 8.78e-6 Blood pressure (smoking interaction); TGCT cis rs2243480 1.000 rs35432774 chr7:65393019 G/C cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs6121246 0.567 rs6087701 chr20:30217708 A/C cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs17102423 0.661 rs4468529 chr14:65611968 C/T cg11161011 chr14:65562177 MAX -0.45 -5.79 -0.46 5.53e-8 Obesity-related traits; TGCT trans rs1814175 0.781 rs28681334 chr11:50051177 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs9400467 0.537 rs1891387 chr6:111462290 A/G cg15721981 chr6:111408429 SLC16A10 0.68 4.48 0.37 1.69e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs6570726 0.935 rs395948 chr6:145820185 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10206020 0.921 rs2280127 chr2:1546531 C/T cg01028140 chr2:1542097 TPO -0.33 -4.72 -0.39 6.17e-6 IgG glycosylation; TGCT cis rs2075371 0.863 rs12707139 chr7:133954153 A/G cg11752832 chr7:134001865 SLC35B4 0.66 5.52 0.44 1.93e-7 Mean platelet volume; TGCT cis rs2300747 0.872 rs1034919 chr1:117075505 G/C cg26677431 chr1:117075710 CD58 -0.23 -4.56 -0.38 1.23e-5 Primary biliary cholangitis;Multiple sclerosis; TGCT cis rs7208859 0.623 rs73271872 chr17:29152228 C/G cg14008862 chr17:28927542 LRRC37B2 0.75 5.06 0.41 1.5e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1215050 0.765 rs1588018 chr4:98756324 G/C cg17366294 chr4:99064904 C4orf37 0.52 5.57 0.45 1.54e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.92 7.33 0.55 2.53e-11 Platelet count; TGCT cis rs875971 0.862 rs7803416 chr7:65954199 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs10934753 0.632 rs13070856 chr3:125909415 A/G cg01346077 chr3:125931526 NA -0.4 -6.48 -0.5 1.95e-9 Plasma homocysteine levels (post-methionine load test); TGCT cis rs7647973 0.587 rs10452032 chr3:49680973 G/A cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg21016266 chr12:122356598 WDR66 0.52 7.48 0.56 1.17e-11 Mean corpuscular volume; TGCT cis rs116095464 0.558 rs6555055 chr5:226160 A/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs6121246 0.529 rs6060171 chr20:30183269 C/T cg18721089 chr20:30220636 NA -0.63 -6.86 -0.52 2.95e-10 Mean corpuscular hemoglobin; TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 4.98 0.41 2.09e-6 Prudent dietary pattern; TGCT cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg18402987 chr7:1209562 NA 0.39 4.99 0.41 1.97e-6 Longevity;Endometriosis; TGCT cis rs933688 0.938 rs12110065 chr5:90718474 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.98 8.36 0.6 1.11e-13 Smoking behavior; TGCT cis rs11190604 1.000 rs10883504 chr10:102280687 G/A cg23241863 chr10:102295624 HIF1AN 0.67 5.11 0.42 1.21e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2836974 0.604 rs2854727 chr21:40713787 A/G cg11890956 chr21:40555474 PSMG1 0.75 7.44 0.56 1.47e-11 Cognitive function; TGCT trans rs877282 0.891 rs10904557 chr10:797490 C/T cg22713356 chr15:30763199 NA -1.19 -11.51 -0.72 2.73e-21 Uric acid levels; TGCT cis rs7524258 1.000 rs7524258 chr1:7292229 T/C cg07173049 chr1:7289937 CAMTA1 0.28 4.74 0.39 5.64e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs514406 0.825 rs487453 chr1:53271225 T/C cg22166914 chr1:53195759 ZYG11B -0.38 -6.45 -0.5 2.23e-9 Monocyte count; TGCT cis rs7617773 0.817 rs9819094 chr3:48319558 C/T cg11946769 chr3:48343235 NME6 0.68 5.94 0.47 2.62e-8 Coronary artery disease; TGCT cis rs4886920 0.519 rs75789686 chr15:78113577 A/G cg25212270 chr15:78015279 NA 0.36 5.39 0.44 3.38e-7 Neuroticism; TGCT cis rs2806561 0.796 rs1738467 chr1:23506521 C/T cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs10851411 0.862 rs11022 chr15:42824578 T/C cg23803468 chr15:43513504 EPB42 0.29 5.38 0.43 3.6e-7 Glucose homeostasis traits; TGCT trans rs2727020 0.595 rs10839281 chr11:49483373 A/C cg03929089 chr4:120376271 NA -0.78 -9.57 -0.65 1.37e-16 Coronary artery disease; TGCT cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg09222892 chr1:25734099 RHCE -0.43 -7.21 -0.54 4.72e-11 Erythrocyte sedimentation rate; TGCT cis rs7666738 0.753 rs10029372 chr4:98859002 T/C cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.764 rs6784111 chr3:49178846 T/C cg16497277 chr3:49208875 KLHDC8B -0.5 -4.55 -0.38 1.25e-5 Parkinson's disease; TGCT cis rs62064224 0.589 rs756785 chr17:30812845 T/C cg18200150 chr17:30822561 MYO1D 0.42 4.96 0.41 2.25e-6 Schizophrenia; TGCT cis rs769267 0.792 rs4808961 chr19:19577215 C/G cg03709012 chr19:19516395 GATAD2A 0.77 6.44 0.5 2.38e-9 Tonsillectomy; TGCT cis rs2708977 0.899 rs12992413 chr2:97277489 A/G cg01950434 chr2:97203154 ARID5A 0.63 5.73 0.46 7.35e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs5769707 0.632 rs6009782 chr22:50010812 C/G cg05373962 chr22:49881684 NA -0.29 -4.97 -0.41 2.16e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2742234 1.000 rs2742234 chr10:43612609 A/G cg02780029 chr10:43622663 RET 0.23 4.69 0.39 7.03e-6 Hirschsprung disease; TGCT cis rs10984561 0.881 rs1331595 chr9:122254605 T/C cg14242995 chr9:122249943 NA 0.72 5.82 0.46 4.75e-8 Pulmonary function decline; TGCT cis rs8020441 0.541 rs8012745 chr14:51160753 G/A cg04730355 chr14:51134070 SAV1 1.17 9.45 0.65 2.78e-16 Cognitive performance; TGCT cis rs473651 0.935 rs520765 chr2:239354712 C/T cg18131467 chr2:239335373 ASB1 1.03 15.56 0.81 6.07e-31 Multiple system atrophy; TGCT cis rs12188164 0.965 rs11743639 chr5:450710 C/T cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs3796352 0.571 rs11713926 chr3:53155072 C/T cg27565382 chr3:53032988 SFMBT1 0.44 5.06 0.41 1.48e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs425277 0.628 rs10797427 chr1:2060732 C/T cg03732007 chr1:2071316 PRKCZ -0.27 -6.21 -0.49 7.18e-9 Height; TGCT cis rs2404602 0.692 rs35138393 chr15:76977617 G/A cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs4144743 1.000 rs4541130 chr17:45321037 G/A cg18085866 chr17:45331354 ITGB3 -0.72 -4.85 -0.4 3.61e-6 Body mass index; TGCT cis rs1903068 0.719 rs73236106 chr4:55996712 C/T cg16572876 chr4:56024045 NA 0.42 4.74 0.39 5.64e-6 Endometriosis; TGCT cis rs12762955 0.561 rs4880744 chr10:1012026 A/G cg26597838 chr10:835615 NA -0.46 -6.19 -0.49 7.94e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs561341 0.528 rs11650908 chr17:30195425 T/C cg13647721 chr17:30228624 UTP6 -0.6 -4.66 -0.39 8.03e-6 Hip circumference adjusted for BMI; TGCT cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg15782153 chr7:917662 C7orf20 -0.44 -5.35 -0.43 4.07e-7 Perceived unattractiveness to mosquitoes; TGCT cis rs1801251 0.928 rs737028 chr2:233640750 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.52 0.51 1.58e-9 Coronary artery disease; TGCT cis rs7666738 0.830 rs6854902 chr4:99033416 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1205863 1.000 rs1205874 chr6:11945478 C/G cg07106625 chr6:11870215 NA 0.49 5.04 0.41 1.57e-6 Disc degeneration (lumbar); TGCT cis rs9393777 0.513 rs13210025 chr6:26654817 A/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.593 rs1877186 chr4:152692418 C/G cg22705602 chr4:152727874 NA -0.34 -5.9 -0.47 3.24e-8 Intelligence (multi-trait analysis); TGCT cis rs4073582 1.000 rs524859 chr11:66041079 G/A cg16950941 chr11:66035639 RAB1B 0.55 4.89 0.4 3.1e-6 Gout; TGCT cis rs4975616 0.710 rs27996 chr5:1345474 A/G cg26373071 chr5:1325741 CLPTM1L 0.16 4.66 0.39 8.14e-6 Lung cancer; TGCT cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.79e-6 Obesity-related traits; TGCT cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs7255045 0.700 rs11085818 chr19:12952271 G/A cg23899408 chr19:12877188 HOOK2 -0.61 -4.94 -0.41 2.48e-6 Mean corpuscular volume; TGCT cis rs3862260 0.509 rs10754416 chr1:120163531 A/G cg16322792 chr1:120165303 ZNF697 0.35 8.49 0.61 5.44e-14 Systemic lupus erythematosus; TGCT cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg23172400 chr8:95962367 TP53INP1 -0.4 -6.56 -0.51 1.33e-9 Type 2 diabetes; TGCT cis rs682748 0.846 rs13175997 chr5:17160258 A/G cg23987134 chr5:17158319 LOC285696 -0.22 -5.36 -0.43 3.85e-7 Hippocampal atrophy; TGCT cis rs732765 0.734 rs6574189 chr14:75166493 C/T cg06637938 chr14:75390232 RPS6KL1 0.6 5.14 0.42 1.06e-6 Non-small cell lung cancer; TGCT cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1018836 0.599 rs9643295 chr8:91492283 T/G cg16814680 chr8:91681699 NA -0.68 -6.83 -0.52 3.31e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10949834 0.504 rs150862 chr7:73524207 C/T cg07137043 chr7:73588983 EIF4H 0.7 5.44 0.44 2.71e-7 Verbal memory performance (residualized delayed recall change); TGCT cis rs10986311 0.802 rs1323761 chr9:127116942 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.75 0.39 5.63e-6 Vitiligo; TGCT cis rs76419734 0.510 rs2216515 chr4:106750214 C/T cg24545054 chr4:106630052 GSTCD;INTS12 -0.7 -4.52 -0.38 1.43e-5 Post bronchodilator FEV1; TGCT cis rs2982552 0.805 rs3020345 chr6:152056368 T/G cg22157087 chr6:152012887 ESR1 0.21 5.25 0.43 6.29e-7 Bone properties (heel); TGCT cis rs736408 0.608 rs2239547 chr3:52855229 T/C cg11645453 chr3:52864694 ITIH4 0.31 5.34 0.43 4.24e-7 Bipolar disorder; TGCT cis rs911186 0.730 rs2393911 chr6:27057079 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.57 -5.64 -0.45 1.08e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs4332037 0.539 rs55790766 chr7:2021248 C/T cg10840412 chr1:235813424 GNG4 0.93 6.69 0.51 6.97e-10 Bipolar disorder; TGCT cis rs9303401 0.614 rs34058624 chr17:57118121 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.56 5.59 0.45 1.4e-7 Cognitive test performance; TGCT cis rs909674 0.690 rs5750823 chr22:39829973 C/T cg24399712 chr22:39784796 NA -1.06 -10.99 -0.7 4.84e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs317689 0.918 rs610192 chr12:69739941 T/C cg20891283 chr12:69753455 YEATS4 0.58 4.72 0.39 6.28e-6 Response to diuretic therapy; TGCT cis rs228437 0.565 rs6569957 chr6:134939559 C/G cg09872934 chr6:134495829 SGK1 -0.53 -4.54 -0.38 1.32e-5 Melanoma; TGCT cis rs7412746 0.658 rs11589458 chr1:150792616 A/G cg09365446 chr1:150670422 GOLPH3L 0.37 5.5 0.44 2.12e-7 Melanoma; TGCT cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.6 -0.65 1.15e-16 Platelet count; TGCT cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.22 0.42 7.2e-7 Height; TGCT trans rs225245 0.531 rs321609 chr17:33880676 G/T cg19694781 chr19:47549865 TMEM160 -0.39 -7.18 -0.54 5.68e-11 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs12477438 0.520 rs2516829 chr2:99773201 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.84 8.1 0.59 4.42e-13 Chronic sinus infection; TGCT cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs597539 0.652 rs544370 chr11:68653232 C/T cg21963583 chr11:68658836 MRPL21 0.37 6.24 0.49 6.47e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7528684 0.752 rs2873413 chr1:157737504 G/A cg17134153 chr1:157670328 FCRL3 -0.27 -4.86 -0.4 3.48e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs9972944 0.756 rs6504353 chr17:63768013 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs7267979 1.000 rs453329 chr20:25440593 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs595982 0.546 rs12461075 chr19:49399821 G/A cg11637076 chr19:49575188 KCNA7 -0.44 -5.23 -0.43 6.99e-7 Red cell distribution width; TGCT cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg02458000 chr6:26745757 NA 0.53 5.07 0.41 1.41e-6 Intelligence (multi-trait analysis); TGCT cis rs4517514 0.509 rs4385851 chr11:89870750 C/T cg05041596 chr11:89867385 NAALAD2 0.52 4.61 0.38 9.86e-6 Trans fatty acid levels; TGCT cis rs2404618 0.624 rs7012381 chr8:1475357 C/T cg13402656 chr8:1511478 DLGAP2 -0.34 -5.64 -0.45 1.09e-7 Lung cancer; TGCT trans rs7698623 0.850 rs4693194 chr4:88798005 T/C cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs12681287 0.640 rs12544463 chr8:87481114 A/G cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs933688 1.000 rs10058025 chr5:90689052 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.91e-14 Smoking behavior; TGCT cis rs881375 0.934 rs2159778 chr9:123678129 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 5.02 0.41 1.74e-6 Rheumatoid arthritis; TGCT cis rs1371867 0.846 rs1788196 chr8:101290088 C/T cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs3812831 0.661 rs2987458 chr13:114919835 A/G cg15513719 chr13:114904418 NA 0.38 4.7 0.39 6.86e-6 Schizophrenia; TGCT cis rs919433 0.519 rs700658 chr2:198655007 A/T cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs514406 0.929 rs12410420 chr1:53323754 T/C cg01802117 chr1:53393560 SCP2 -0.39 -4.55 -0.38 1.27e-5 Monocyte count; TGCT cis rs377070 0.966 rs309419 chr4:123624001 C/G cg10495464 chr4:123653540 BBS12;LOC729338 0.46 5.03 0.41 1.67e-6 Mosquito bite size; TGCT cis rs13242816 1.000 rs67982517 chr7:116075363 A/G cg02799643 chr7:116139180 CAV2 -0.43 -5.08 -0.42 1.33e-6 P wave duration; TGCT cis rs2594989 0.779 rs7647622 chr3:11590871 G/A cg00170343 chr3:11313890 ATG7 -0.7 -5.24 -0.43 6.66e-7 Circulating chemerin levels; TGCT cis rs6952808 0.636 rs6461005 chr7:1947687 A/G cg04267008 chr7:1944627 MAD1L1 -0.36 -4.72 -0.39 6.34e-6 Bipolar disorder and schizophrenia; TGCT cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs7914558 0.966 rs10748837 chr10:104880236 T/C cg15744005 chr10:104629667 AS3MT -0.42 -5.21 -0.42 7.57e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17376456 0.877 rs10076052 chr5:93317762 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs9611519 0.964 rs5995992 chr22:41487218 T/C cg03806693 chr22:41940476 POLR3H -0.67 -6.21 -0.49 7.16e-9 Neuroticism; TGCT cis rs2594989 0.943 rs9877694 chr3:11418873 A/C cg00170343 chr3:11313890 ATG7 0.64 4.89 0.4 3.04e-6 Circulating chemerin levels; TGCT cis rs10509586 0.826 rs60623262 chr10:91899317 G/A cg25278353 chr10:91717815 NA 0.49 4.67 0.39 7.77e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs7523273 0.606 rs2724382 chr1:207928635 G/C cg22525895 chr1:207977042 MIR29B2 0.51 8.25 0.6 1.98e-13 Schizophrenia; TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs858239 0.899 rs2268747 chr7:23313462 A/G cg05602783 chr7:23145260 KLHL7 -0.66 -5.25 -0.43 6.38e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2204008 0.775 rs3900361 chr12:38238936 A/G cg26384229 chr12:38710491 ALG10B -0.83 -7.18 -0.54 5.51e-11 Bladder cancer; TGCT cis rs2292864 0.764 rs1969269 chr17:45335537 C/A cg17233517 chr17:45285328 MYL4 0.37 4.59 0.38 1.09e-5 Left atrial antero-posterior diameter; TGCT cis rs13064411 0.696 rs869342 chr3:113226330 C/T cg18753928 chr3:113234510 CCDC52 -0.71 -5.78 -0.46 5.63e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs8031584 0.706 rs798084 chr15:31126935 C/T cg14829155 chr15:31115871 NA -0.38 -5.03 -0.41 1.69e-6 Huntington's disease progression; TGCT cis rs372883 0.648 rs382732 chr21:30719010 A/G cg24692254 chr21:30365293 RNF160 0.53 4.86 0.4 3.53e-6 Pancreatic cancer; TGCT cis rs8078723 1.000 rs4795412 chr17:38150604 C/T cg17467752 chr17:38218738 THRA 0.55 5.34 0.43 4.37e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs9527 0.637 rs7096169 chr10:104618695 A/G cg04362960 chr10:104952993 NT5C2 0.56 4.89 0.4 3.06e-6 Arsenic metabolism; TGCT cis rs4819052 0.807 rs4819047 chr21:46665139 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.6 5.08 0.41 1.37e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4819052 0.851 rs28442024 chr21:46674475 C/A cg06618935 chr21:46677482 NA -0.36 -5.39 -0.44 3.4e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs7819412 0.511 rs2409797 chr8:11433780 T/C cg15556689 chr8:8085844 FLJ10661 -0.77 -7.09 -0.54 9.07e-11 Triglycerides; TGCT cis rs9325144 0.723 rs11169519 chr12:39177441 G/A cg26384229 chr12:38710491 ALG10B -0.62 -5.85 -0.46 4.15e-8 Morning vs. evening chronotype; TGCT cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.69 5.32 0.43 4.67e-7 Lung function (FEV1/FVC); TGCT cis rs1986116 0.773 rs12588022 chr14:77518576 G/C cg04913803 chr14:77510549 NA 0.39 4.51 0.38 1.46e-5 Sleep quality; TGCT cis rs6032067 0.602 rs2741523 chr20:43920446 C/T cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -7.0 -0.53 1.41e-10 Blood protein levels; TGCT cis rs7590720 0.731 rs1864253 chr2:216878008 C/G cg12620499 chr2:216877984 MREG 0.96 13.29 0.77 1.31e-25 Alcohol dependence; TGCT cis rs35306767 0.761 rs12770910 chr10:1050318 A/G cg26597838 chr10:835615 NA 0.6 6.63 0.51 9.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs9486719 1.000 rs926276 chr6:96868735 C/T cg18709589 chr6:96969512 KIAA0776 0.67 5.23 0.43 7e-7 Migraine;Coronary artery disease; TGCT cis rs2302045 1.000 rs2302048 chr2:242062117 G/A cg04553960 chr2:241721320 KIF1A -0.69 -4.74 -0.39 5.8e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs11585357 0.947 rs11585119 chr1:17605792 C/A cg08277548 chr1:17600880 PADI3 -0.97 -9.95 -0.67 1.7e-17 Hair shape; TGCT cis rs13191362 0.935 rs67337490 chr6:162953961 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.67 5.16 0.42 9.64e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs231513 0.954 rs231524 chr17:41953212 G/A cg26893861 chr17:41843967 DUSP3 -0.87 -6.27 -0.49 5.58e-9 Cognitive function; TGCT cis rs3733585 0.673 rs7378340 chr4:9955198 C/T cg00071950 chr4:10020882 SLC2A9 -0.58 -6.85 -0.52 3.02e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6951245 0.935 rs11763765 chr7:1060510 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.56 -0.38 1.19e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6725041 0.792 rs1546719 chr2:213088582 G/C cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs8077889 0.645 rs1230393 chr17:41842592 A/G cg26893861 chr17:41843967 DUSP3 -1.15 -21.87 -0.89 2.21e-44 Triglycerides; TGCT cis rs9303542 0.527 rs8074125 chr17:46610060 G/T cg25032089 chr17:46643351 HOXB3 0.58 5.47 0.44 2.38e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs853679 0.546 rs200490 chr6:27796935 G/T cg08798685 chr6:27730294 NA -0.36 -5.0 -0.41 1.91e-6 Depression; TGCT cis rs12477438 0.520 rs4850897 chr2:99768419 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs9942416 0.660 rs67054144 chr5:74991443 G/A cg19683494 chr5:74908142 NA 0.59 6.26 0.49 5.62e-9 Age-related disease endophenotypes; TGCT cis rs9486719 0.947 rs9386648 chr6:97035656 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs9911578 0.730 rs55759249 chr17:57027135 A/G cg05425664 chr17:57184151 TRIM37 0.57 4.62 0.38 9.42e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs2259928 chr20:25281834 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9911578 0.967 rs8072712 chr17:57162464 A/T cg05425664 chr17:57184151 TRIM37 -0.68 -6.9 -0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs6570726 1.000 rs444564 chr6:145859795 G/C cg23711669 chr6:146136114 FBXO30 0.71 6.66 0.51 7.78e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg14983838 chr19:29218262 NA 0.86 7.07 0.54 9.71e-11 Methadone dose in opioid dependence; TGCT cis rs10486607 0.789 rs12700934 chr7:29179168 A/C cg11251470 chr7:30008931 SCRN1 0.3 4.44 0.37 1.95e-5 Diabetes related insulin traits; TGCT cis rs7923609 0.967 rs7085018 chr10:65286667 T/C cg08743896 chr10:65200160 JMJD1C -0.33 -4.48 -0.37 1.69e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs7819412 0.527 rs7821914 chr8:10805015 A/G cg21775007 chr8:11205619 TDH -0.58 -5.5 -0.44 2.11e-7 Triglycerides; TGCT cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs7772486 0.774 rs2748503 chr6:146295042 T/C cg23711669 chr6:146136114 FBXO30 0.71 6.6 0.51 1.06e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6912958 0.558 rs9444530 chr6:88343318 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.5 4.51 0.38 1.48e-5 Monocyte percentage of white cells; TGCT cis rs7845219 0.525 rs3019175 chr8:95949013 G/A cg16049864 chr8:95962084 TP53INP1 -0.49 -5.34 -0.43 4.27e-7 Type 2 diabetes; TGCT cis rs904251 0.797 rs1757181 chr6:37485728 A/G cg08126542 chr6:37504118 NA 0.4 5.4 0.44 3.25e-7 Cognitive performance; TGCT trans rs1005277 0.579 rs176838 chr10:38371899 A/T cg27523141 chr10:43048294 ZNF37B -0.74 -7.98 -0.58 8.18e-13 Extrinsic epigenetic age acceleration; TGCT cis rs854765 0.624 rs12938501 chr17:17737258 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.52 -0.5 1.64e-9 Total body bone mineral density; TGCT cis rs2842992 0.830 rs2495279 chr6:160138796 C/T cg11366901 chr6:160182831 ACAT2 1.01 6.74 0.52 5.42e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs6840360 0.571 rs2407069 chr4:152533201 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.851 rs4390625 chr17:37620347 A/G cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT trans rs6089829 0.962 rs6062776 chr20:61663736 A/G cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.92 0.4 2.68e-6 Menopause (age at onset); TGCT cis rs9611565 0.918 rs2281333 chr22:41749630 T/C cg17554472 chr22:41940697 POLR3H -0.46 -4.98 -0.41 2.07e-6 Vitiligo; TGCT cis rs7119 0.717 rs62009070 chr15:77817884 G/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs950169 0.840 rs2896002 chr15:84945121 A/G cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs7666738 0.830 rs4699584 chr4:98952019 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11764590 0.950 rs55683212 chr7:2078855 G/C cg25834613 chr7:1915315 MAD1L1 -0.52 -5.11 -0.42 1.2e-6 Neuroticism; TGCT cis rs8072100 0.875 rs4794047 chr17:45763005 A/T cg08085267 chr17:45401833 C17orf57 0.49 5.19 0.42 8.18e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9814567 1.000 rs13081177 chr3:134289860 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs8103278 1.000 rs8109951 chr19:46289503 C/T cg11657440 chr19:46296263 DMWD -0.59 -5.72 -0.46 7.41e-8 Coronary artery disease; TGCT cis rs6840360 0.550 rs4696269 chr4:152481704 T/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs17331151 0.573 rs28552648 chr3:52865593 G/A cg07884673 chr3:53033167 SFMBT1 0.49 5.66 0.45 1.01e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs921968 0.643 rs3932856 chr2:219320207 C/A cg02176678 chr2:219576539 TTLL4 0.45 6.37 0.5 3.34e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs782590 0.764 rs2586970 chr2:55829967 A/G cg03859395 chr2:55845619 SMEK2 0.84 10.09 0.67 7.69e-18 Metabolic syndrome; TGCT cis rs2067615 0.507 rs10746064 chr12:107086245 G/T cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT trans rs3780486 0.813 rs3780488 chr9:33133812 T/C cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs6598955 0.671 rs12088858 chr1:26643708 C/A cg04990556 chr1:26633338 UBXN11 0.62 4.6 0.38 1.04e-5 Obesity-related traits; TGCT cis rs651907 0.557 rs34457525 chr3:101435225 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 10.45 0.68 1.02e-18 Colorectal cancer; TGCT cis rs7666738 1.000 rs7666738 chr4:98968077 C/T cg18180107 chr4:99064573 C4orf37 0.56 4.54 0.38 1.34e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs10254284 1.000 rs4722756 chr7:28154822 A/G cg23620719 chr7:28220237 JAZF1 -0.52 -4.58 -0.38 1.1e-5 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs9308731 0.623 rs11674517 chr2:111903832 C/T cg04202892 chr2:111875749 ACOXL 0.55 6.36 0.5 3.45e-9 Chronic lymphocytic leukemia; TGCT cis rs7191700 0.601 rs243329 chr16:11352313 A/T cg00044050 chr16:11439710 C16orf75 0.85 8.8 0.62 9.64e-15 Multiple sclerosis; TGCT cis rs344364 0.511 rs1742460 chr16:1945441 G/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg02503808 chr4:7069936 GRPEL1 0.98 9.23 0.64 9.22e-16 Monocyte percentage of white cells; TGCT cis rs7647973 1.000 rs11928090 chr3:49604904 G/A cg05785598 chr3:49045655 WDR6 0.37 4.59 0.38 1.05e-5 Menarche (age at onset); TGCT cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg11062466 chr8:58055876 NA 0.43 4.95 0.41 2.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs9660992 0.573 rs12125276 chr1:205199440 C/T cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs7824557 0.547 rs2736287 chr8:11228006 G/A cg21775007 chr8:11205619 TDH -0.75 -7.89 -0.58 1.32e-12 Retinal vascular caliber; TGCT cis rs2153535 0.580 rs6597334 chr6:8504779 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9921222 0.500 rs12917907 chr16:405866 C/T cg15001381 chr16:403314 AXIN1 0.31 4.79 0.4 4.66e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs7474896 0.537 rs2472149 chr10:38262196 A/C cg13720705 chr10:37990370 NA -0.34 -4.6 -0.38 1.04e-5 Obesity (extreme); TGCT cis rs9468199 0.523 rs9468152 chr6:27492906 A/C cg21504815 chr6:27791876 HIST1H4J -0.71 -4.93 -0.4 2.57e-6 Parkinson's disease; TGCT cis rs2224391 0.554 rs2224392 chr6:5261136 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.02 -6.38 -0.5 3.19e-9 Height; TGCT cis rs13088645 0.532 rs12695612 chr3:134161824 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.66 6.03 0.48 1.71e-8 Coronary artery disease; TGCT cis rs6754311 0.593 rs313528 chr2:136445869 G/A cg07169764 chr2:136633963 MCM6 0.69 6.28 0.49 5.13e-9 Mosquito bite size; TGCT cis rs7089973 0.604 rs3758603 chr10:116605368 T/C cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7208859 0.673 rs423151 chr17:28952286 A/G cg14008862 chr17:28927542 LRRC37B2 0.69 4.57 0.38 1.16e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs425277 0.538 rs169037 chr1:2095582 G/T cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.46 -0.37 1.81e-5 Height; TGCT cis rs7662987 0.517 rs2602866 chr4:100034997 A/G cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs4930561 1.000 rs4930561 chr11:67931761 C/T cg04465784 chr11:67976953 SUV420H1 -0.34 -4.44 -0.37 2e-5 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs3008870 0.755 rs1925409 chr1:67365089 C/T cg08660285 chr1:67390436 MIER1;WDR78 -0.76 -8.12 -0.59 3.89e-13 Lymphocyte percentage of white cells; TGCT cis rs11779988 0.545 rs4124900 chr8:17785266 A/G cg01800426 chr8:17659068 MTUS1 -0.7 -5.46 -0.44 2.5e-7 Breast cancer; TGCT cis rs921968 0.541 rs10205073 chr2:219412784 C/A cg02176678 chr2:219576539 TTLL4 -0.49 -6.94 -0.53 1.95e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs12134133 1.000 rs2490261 chr1:207477469 T/C cg02152968 chr1:207494213 CD55 0.56 4.59 0.38 1.08e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs854765 0.592 rs2955367 chr17:18024266 T/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.7 7.26 0.55 3.74e-11 Total body bone mineral density; TGCT cis rs7714584 1.000 rs34156253 chr5:150226230 A/G cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs2842992 0.724 rs9347340 chr6:160188891 C/T cg11366901 chr6:160182831 ACAT2 -0.73 -5.61 -0.45 1.25e-7 Age-related macular degeneration (geographic atrophy); TGCT cis rs17423910 1.000 rs17423910 chr1:66689109 C/T cg04880992 chr1:67434664 MIER1 0.33 4.69 0.39 7.13e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs10089 0.953 rs758180 chr5:127354423 T/A cg19767477 chr5:127420684 SLC12A2 -0.42 -4.44 -0.37 2e-5 Ileal carcinoids; TGCT cis rs7089973 0.668 rs7898347 chr10:116644324 G/A cg03647239 chr10:116582469 FAM160B1 0.58 5.42 0.44 2.94e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs2228479 0.618 rs17233623 chr16:89811209 C/T cg06558623 chr16:89946397 TCF25 0.45 4.54 0.38 1.31e-5 Skin colour saturation; TGCT cis rs4665809 1.000 rs6709595 chr2:26259885 A/G cg04944784 chr2:26401820 FAM59B -0.67 -5.98 -0.47 2.23e-8 Gut microbiome composition (summer); TGCT cis rs11671005 0.693 rs11084542 chr19:58932099 T/A cg13877915 chr19:58951672 ZNF132 0.65 5.08 0.41 1.37e-6 Mean platelet volume; TGCT cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg07341220 chr16:1583899 IFT140;TMEM204 -0.3 -4.72 -0.39 6.18e-6 Coronary artery disease; TGCT cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg00484396 chr16:3507460 NAT15 -0.44 -6.78 -0.52 4.36e-10 Tuberculosis; TGCT cis rs7698623 0.850 rs4693195 chr4:88798211 G/A cg02735620 chr4:88950514 PKD2 -0.44 -4.77 -0.39 5.18e-6 Cardiovascular disease risk factors; TGCT cis rs2274273 0.743 rs13379159 chr14:55540801 C/T cg01923255 chr14:55878535 KIAA0831 0.57 4.89 0.4 3.03e-6 Protein biomarker; TGCT cis rs7772486 0.902 rs2748500 chr6:146314852 C/A cg23711669 chr6:146136114 FBXO30 0.77 7.93 0.58 1.08e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs6835098 0.924 rs13138282 chr4:174120906 C/T cg08422745 chr4:174089978 GALNT7 0.89 10.03 0.67 1.05e-17 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs56235845 0.685 rs35630910 chr5:176757841 A/C cg06060754 chr5:176797920 RGS14 0.44 6.75 0.52 5.06e-10 Hemoglobin concentration;Hematocrit; TGCT cis rs12477438 0.798 rs6732579 chr2:99560239 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.67 -5.66 -0.45 1e-7 Chronic sinus infection; TGCT cis rs513349 0.964 rs210141 chr6:33546825 T/C cg24505687 chr6:33548425 BAK1 0.52 6.47 0.5 2.04e-9 Platelet count; TGCT cis rs9303401 0.573 rs62081879 chr17:57181524 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs7772486 0.754 rs9390356 chr6:146118983 A/T cg05347473 chr6:146136440 FBXO30 -0.53 -4.99 -0.41 2.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6570726 0.791 rs385729 chr6:145855465 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2050392 0.517 rs602966 chr10:30755853 C/T cg13289132 chr10:30722225 MAP3K8 -0.39 -4.6 -0.38 1.04e-5 Inflammatory bowel disease; TGCT cis rs2688608 0.901 rs2633312 chr10:75631755 T/A cg04320760 chr10:75533139 FUT11 -0.32 -4.93 -0.4 2.61e-6 Inflammatory bowel disease; TGCT cis rs10876993 0.821 rs1678522 chr12:58049923 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs1215050 0.904 rs9307215 chr4:98813965 A/G cg17366294 chr4:99064904 C4orf37 0.5 4.99 0.41 1.95e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3733585 0.604 rs73215003 chr4:10126317 C/G cg00071950 chr4:10020882 SLC2A9 -0.49 -5.15 -0.42 1.01e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12477438 0.520 rs2632277 chr2:99778985 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.3 0.64 6.31e-16 Chronic sinus infection; TGCT cis rs12477438 0.520 rs34766932 chr2:99737273 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs1865760 1.000 rs3799372 chr6:25922311 A/G cg16482183 chr6:26056742 HIST1H1C 0.51 4.59 0.38 1.06e-5 Height; TGCT cis rs2841277 0.708 rs11851053 chr14:105407208 T/C cg19901468 chr14:105411992 AHNAK2 -0.28 -6.09 -0.48 1.31e-8 Rheumatoid arthritis; TGCT cis rs4824093 0.610 rs4824113 chr22:50284974 C/T cg14114931 chr22:50943910 LMF2 0.37 4.56 0.38 1.22e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs3924048 0.574 rs12062307 chr1:12611852 C/T cg00291366 chr1:12616550 NA 0.32 4.87 0.4 3.34e-6 Optic cup area; TGCT cis rs7726839 0.540 rs12517638 chr5:645484 C/T cg09021430 chr5:549028 NA -0.39 -5.37 -0.43 3.77e-7 Obesity-related traits; TGCT cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1008375 0.800 rs62296338 chr4:17613425 G/T cg16339924 chr4:17578868 LAP3 0.7 5.5 0.44 2.12e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs16957091 0.647 rs28374998 chr15:43289177 C/G cg17935677 chr15:44119062 WDR76 0.54 4.87 0.4 3.38e-6 MGMT methylation in smokers; TGCT cis rs6840360 0.571 rs10026670 chr4:152539212 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.904 rs7218379 chr17:28402737 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.82 -7.84 -0.58 1.8e-12 Coffee consumption (cups per day); TGCT cis rs3733585 0.699 rs12498150 chr4:9950537 C/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.43 -0.5 2.49e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13326165 0.709 rs6796333 chr3:52359678 T/C cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs11209185 0.509 rs9436789 chr1:68441456 G/A cg22082780 chr1:68452167 NA 0.31 4.68 0.39 7.28e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs56235845 0.694 rs6875461 chr5:176754665 C/T cg17509989 chr5:176798049 RGS14 -0.54 -7.4 -0.55 1.78e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs7439150 0.909 rs2227426 chr4:155493171 A/G cg22130008 chr4:155548532 NA 0.39 4.84 0.4 3.8e-6 Fibrinogen levels; TGCT cis rs4240897 0.835 rs4845891 chr1:12042506 T/C cg13216073 chr1:12042593 MFN2 0.19 5.6 0.45 1.34e-7 Tuberculosis; TGCT cis rs9910055 0.529 rs400460 chr17:42182770 A/G cg13607699 chr17:42295918 UBTF -0.64 -5.52 -0.44 1.87e-7 Total body bone mineral density; TGCT cis rs854765 0.624 rs11657423 chr17:17728574 T/C cg09796270 chr17:17721594 SREBF1 -0.27 -5.21 -0.42 7.54e-7 Total body bone mineral density; TGCT cis rs8026198 0.568 rs58712247 chr15:42616288 C/CA cg23803468 chr15:43513504 EPB42 0.44 5.28 0.43 5.55e-7 Fibrinogen levels; TGCT cis rs78487399 0.908 rs17031088 chr2:43807090 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.65 0.39 8.32e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6545883 0.895 rs2421192 chr2:61643631 T/C cg15711740 chr2:61764176 XPO1 0.53 4.75 0.39 5.51e-6 Tuberculosis; TGCT cis rs2594989 0.780 rs2454477 chr3:11555842 G/A cg26283222 chr3:11613257 VGLL4 -0.25 -5.35 -0.43 4.07e-7 Circulating chemerin levels; TGCT cis rs2657888 0.593 rs2638318 chr12:56857422 C/T cg23002907 chr12:56915593 RBMS2 0.46 6.15 0.48 9.61e-9 Adiponectin levels; TGCT cis rs7904985 0.639 rs12778367 chr10:88116246 A/G cg02632490 chr10:88024529 MIR346;GRID1 -0.28 -4.54 -0.38 1.31e-5 Barrett's esophagus; TGCT cis rs9467773 1.000 rs1321480 chr6:26532742 A/G cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs1448094 0.512 rs7308229 chr12:86239849 A/T cg19622623 chr12:86230825 RASSF9 0.23 4.5 0.37 1.52e-5 Major depressive disorder; TGCT cis rs12478296 1.000 rs67535150 chr2:243046099 A/G cg06360820 chr2:242988706 NA -0.61 -4.64 -0.38 8.65e-6 Obesity-related traits; TGCT cis rs4699052 0.625 rs6822783 chr4:104284924 T/C cg16532752 chr4:104119610 CENPE -0.52 -4.96 -0.41 2.3e-6 Testicular germ cell tumor; TGCT cis rs8180040 0.783 rs11710121 chr3:47351501 T/G cg27129171 chr3:47204927 SETD2 -0.6 -6.53 -0.51 1.5e-9 Colorectal cancer; TGCT cis rs2164273 0.565 rs2736387 chr8:11157371 A/C cg27034466 chr8:11760342 NA 0.19 4.45 0.37 1.91e-5 Extraversion; TGCT cis rs1950500 0.565 rs3181248 chr14:24808168 G/A cg22990158 chr14:24802150 ADCY4 -0.56 -4.98 -0.41 2.07e-6 Height; TGCT cis rs6121246 0.647 rs6088855 chr20:30225792 C/T cg13852791 chr20:30311386 BCL2L1 0.75 4.76 0.39 5.24e-6 Mean corpuscular hemoglobin; TGCT cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg20203395 chr5:56204925 C5orf35 0.6 5.25 0.43 6.37e-7 Initial pursuit acceleration; TGCT cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.84 0.46 4.39e-8 Height; TGCT cis rs1801251 0.929 rs12694917 chr2:233707611 C/T cg08000102 chr2:233561755 GIGYF2 -0.63 -6.42 -0.5 2.58e-9 Coronary artery disease; TGCT cis rs6430585 0.640 rs58301703 chr2:136532225 G/A cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg04267008 chr7:1944627 MAD1L1 -0.38 -5.01 -0.41 1.84e-6 Bipolar disorder and schizophrenia; TGCT cis rs875971 0.522 rs6960048 chr7:65408039 A/G cg18876405 chr7:65276391 NA 0.37 5.89 0.47 3.33e-8 Aortic root size; TGCT cis rs2486012 1.000 rs1548634 chr1:44399608 T/C cg12908607 chr1:44402522 ARTN 0.72 5.74 0.46 6.94e-8 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.623 rs17426903 chr9:5203292 A/C cg02405213 chr9:5042618 JAK2 -0.72 -8.5 -0.61 5.12e-14 Pediatric autoimmune diseases; TGCT cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg07061783 chr6:25882402 NA -0.6 -5.59 -0.45 1.35e-7 Intelligence (multi-trait analysis); TGCT cis rs9969804 0.782 rs10761169 chr9:95515033 T/C cg13940029 chr9:95239186 CENPP;ASPN -0.17 -4.54 -0.38 1.32e-5 Height; TGCT cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.82e-6 Obesity-related traits; TGCT cis rs6429082 0.818 rs291386 chr1:235647050 C/T cg26050004 chr1:235667680 B3GALNT2 0.6 5.36 0.43 3.88e-7 Adiposity; TGCT cis rs854765 0.693 rs9907246 chr17:17770965 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.76 -7.96 -0.58 9.35e-13 Total body bone mineral density; TGCT cis rs7647973 0.626 rs12715437 chr3:49751856 T/C cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs1541995 1.000 rs16975700 chr15:96379923 A/G cg00882281 chr15:96346592 NA -0.28 -4.65 -0.39 8.22e-6 Photic sneeze reflex; TGCT cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs6459788 0.685 rs13226469 chr7:157235777 G/A cg03453431 chr7:157225567 NA -0.47 -7.09 -0.54 8.76e-11 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs60843830 1.000 rs17713396 chr2:227201 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.73 0.57 3.18e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2228479 0.850 rs62054257 chr16:89900195 G/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs1538970 0.884 rs61788261 chr1:45899114 G/A cg05343316 chr1:45956843 TESK2 0.76 6.18 0.49 8.53e-9 Platelet count; TGCT cis rs2692947 0.673 rs3111873 chr2:96781986 G/C cg05933789 chr2:97190408 NA -0.16 -4.56 -0.38 1.19e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7264396 0.570 rs6060717 chr20:34544647 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs7635838 0.819 rs6776159 chr3:11519324 A/G cg00170343 chr3:11313890 ATG7 0.69 6.67 0.51 7.44e-10 HDL cholesterol; TGCT cis rs28595532 1.000 rs28600971 chr4:119712728 G/T cg21605333 chr4:119757512 SEC24D 1.21 6.77 0.52 4.51e-10 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs1834647 chr4:98882915 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.94 0.41 2.42e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12188164 0.561 rs2251843 chr5:457955 C/T cg00049323 chr5:472564 LOC25845 -0.25 -4.45 -0.37 1.87e-5 Cystic fibrosis severity; TGCT cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg15691649 chr6:25882328 NA 0.43 5.34 0.43 4.27e-7 Blood metabolite levels; TGCT cis rs9677476 0.516 rs765458 chr2:231990667 G/A cg07929768 chr2:232055508 NA 0.34 5.26 0.43 6.11e-7 Food antigen IgG levels; TGCT cis rs6909279 0.522 rs7741872 chr6:151893946 C/G cg14416726 chr6:151773293 C6orf211;RMND1 0.56 4.67 0.39 7.84e-6 Bone mineral density; TGCT cis rs7666738 0.830 rs13134216 chr4:98919765 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.23 0.43 6.88e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1005277 0.683 rs7923868 chr10:37989766 T/C cg25427524 chr10:38739819 LOC399744 -0.33 -5.78 -0.46 5.82e-8 Extrinsic epigenetic age acceleration; TGCT cis rs4972806 0.668 rs2072588 chr2:177042930 G/C cg14324370 chr2:177042789 NA 0.74 6.83 0.52 3.32e-10 IgG glycosylation; TGCT cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg11062466 chr8:58055876 NA 0.37 4.53 0.38 1.38e-5 Developmental language disorder (linguistic errors); TGCT cis rs73198271 0.729 rs66564323 chr8:8604996 G/A ch.8.214553F chr8:8189620 PRAGMIN -0.28 -4.79 -0.4 4.63e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2836950 0.585 rs1029004 chr21:40615343 A/G cg11890956 chr21:40555474 PSMG1 -0.68 -6.67 -0.51 7.4e-10 Menarche (age at onset); TGCT cis rs7819412 0.522 rs3021495 chr8:10994743 C/G cg21775007 chr8:11205619 TDH -0.54 -4.87 -0.4 3.33e-6 Triglycerides; TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs17376456 1.000 rs56046246 chr5:93531545 T/G cg21475434 chr5:93447410 FAM172A 0.61 4.51 0.38 1.47e-5 Diabetic retinopathy; TGCT cis rs6061231 1.000 rs13043313 chr20:60958269 A/G cg24112000 chr20:60950667 NA -0.35 -5.07 -0.41 1.42e-6 Colorectal cancer; TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg22166914 chr1:53195759 ZYG11B 0.36 5.96 0.47 2.45e-8 Monocyte count; TGCT cis rs709400 0.597 rs1013650 chr14:103909203 G/A cg26031613 chr14:104095156 KLC1 0.87 9.75 0.66 5.07e-17 Body mass index; TGCT cis rs7666738 0.830 rs1111541 chr4:99033860 A/G cg05340658 chr4:99064831 C4orf37 -0.5 -5.55 -0.45 1.64e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2777491 0.915 rs28526381 chr15:41621842 A/C cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.44 -0.68 1.07e-18 Ulcerative colitis; TGCT cis rs6460942 0.732 rs73677575 chr7:12286532 A/G cg06484146 chr7:12443880 VWDE -0.54 -4.82 -0.4 4.13e-6 Coronary artery disease; TGCT cis rs225245 0.791 rs4796103 chr17:34025182 A/G cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs7937682 1.000 rs7128353 chr11:111538875 A/G cg09085632 chr11:111637200 PPP2R1B -1.02 -9.84 -0.66 3.17e-17 Primary sclerosing cholangitis; TGCT cis rs9611519 0.602 rs8138520 chr22:41412928 A/G cg13695892 chr22:41940480 POLR3H -0.54 -5.1 -0.42 1.21e-6 Neuroticism; TGCT cis rs9393777 0.920 rs66462181 chr6:27091661 T/C cg16898833 chr6:26189333 HIST1H4D 1.29 5.83 0.46 4.6e-8 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg03517284 chr6:25882590 NA -0.64 -5.88 -0.47 3.49e-8 Intelligence (multi-trait analysis); TGCT cis rs9486715 1.000 rs6905568 chr6:97066382 T/C cg18709589 chr6:96969512 KIAA0776 -0.77 -7.12 -0.54 7.74e-11 Headache; TGCT cis rs11696501 0.739 rs2281210 chr20:44243172 T/G cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs7582180 0.739 rs11123822 chr2:100911582 G/T cg14675211 chr2:100938903 LONRF2 0.45 4.49 0.37 1.63e-5 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs875971 0.862 rs778707 chr7:65857027 G/A cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs10057188 1.000 rs1978629 chr5:77862156 C/T cg06873401 chr5:77792105 LHFPL2 0.22 4.46 0.37 1.8e-5 Pulse pressure; TGCT cis rs6424115 1.000 rs12116511 chr1:24162662 A/G cg15997130 chr1:24165203 NA -0.9 -10.28 -0.68 2.61e-18 Immature fraction of reticulocytes; TGCT cis rs2235642 0.893 rs8051295 chr16:1588087 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -4.84 -0.4 3.84e-6 Coronary artery disease; TGCT cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg24531977 chr5:56204891 C5orf35 -0.74 -6.99 -0.53 1.51e-10 Initial pursuit acceleration; TGCT cis rs6831352 0.879 rs56222233 chr4:100069627 T/G cg12011299 chr4:100065546 ADH4 -0.46 -5.22 -0.42 7.38e-7 Alcohol dependence; TGCT cis rs6598955 0.543 rs3795689 chr1:26560366 C/G cg04990556 chr1:26633338 UBXN11 0.83 8.03 0.59 6.27e-13 Obesity-related traits; TGCT cis rs250677 0.522 rs10045726 chr5:148352990 C/T cg18129178 chr5:148520854 ABLIM3 0.38 4.88 0.4 3.23e-6 Breast cancer; TGCT cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg18252515 chr7:66147081 NA -1.08 -6.32 -0.49 4.33e-9 Diabetic kidney disease; TGCT cis rs2797160 0.904 rs1418637 chr6:125992553 A/G cg05901451 chr6:126070800 HEY2 -0.78 -6.85 -0.52 3.01e-10 Endometrial cancer; TGCT cis rs11711311 0.955 rs9866806 chr3:113379865 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.79 7.03 0.53 1.19e-10 IgG glycosylation; TGCT cis rs875971 0.706 rs1643374 chr7:65872682 T/A cg00343986 chr7:65444356 GUSB 0.22 4.69 0.39 7.08e-6 Aortic root size; TGCT cis rs7172809 0.573 rs60079927 chr15:77591614 T/C cg22256960 chr15:77711686 NA -0.47 -4.61 -0.38 9.99e-6 Glucose homeostasis traits; TGCT cis rs5750830 0.649 rs4337572 chr22:39800704 C/G cg02038168 chr22:39784481 NA -0.76 -5.64 -0.45 1.12e-7 Intelligence (multi-trait analysis); TGCT cis rs11098499 0.954 rs2389802 chr4:120325732 C/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.66 -0.39 8.11e-6 Initial pursuit acceleration; TGCT cis rs7553864 0.574 rs6576867 chr1:87615796 A/T cg17420885 chr1:87600446 LOC339524 -0.39 -4.86 -0.4 3.47e-6 Smoking behavior; TGCT cis rs2997447 0.655 rs55820521 chr1:26374286 C/T cg19759804 chr1:25889155 LDLRAP1 0.33 4.48 0.37 1.65e-5 QRS complex (12-leadsum); TGCT cis rs71335811 1 rs71335811 chr19:49130070 TC/T cg07996880 chr19:49339085 HSD17B14 -0.29 -5.05 -0.41 1.56e-6 Myeloid white cell count; TGCT cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg04772025 chr11:68637568 NA 0.62 6.97 0.53 1.69e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1552244 0.572 rs12107622 chr3:10171898 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.93 5.43 0.44 2.89e-7 Alzheimer's disease; TGCT cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg03806693 chr22:41940476 POLR3H 1.04 10.57 0.69 5.2e-19 Crohn's disease;Inflammatory bowel disease; TGCT cis rs904251 1.000 rs10947673 chr6:37445079 C/T cg01843034 chr6:37503916 NA -0.46 -5.44 -0.44 2.72e-7 Cognitive performance; TGCT cis rs9486715 0.838 rs9400034 chr6:96954566 C/T cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.16e-30 Headache; TGCT cis rs3806843 0.576 rs246034 chr5:140332064 A/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10789491 1.000 rs1371834 chr1:47176894 G/A cg15501359 chr1:47185051 KIAA0494 0.81 8.34 0.6 1.19e-13 Response to hepatitis C treatment; TGCT cis rs7914558 1.000 rs6584540 chr10:104927634 A/G cg15744005 chr10:104629667 AS3MT -0.39 -4.75 -0.39 5.53e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs986417 0.818 rs8005621 chr14:61106699 G/A cg27398547 chr14:60952738 C14orf39 1.45 9.82 0.66 3.5e-17 Gut microbiota (bacterial taxa); TGCT cis rs2075671 0.857 rs11772849 chr7:100308412 G/A cg20848291 chr7:100343083 ZAN -0.53 -4.59 -0.38 1.06e-5 Other erythrocyte phenotypes; TGCT cis rs4642101 0.639 rs9870433 chr3:12853566 T/C cg05775895 chr3:12838266 CAND2 0.6 5.97 0.47 2.33e-8 QRS complex (12-leadsum); TGCT cis rs57920188 0.537 rs4347180 chr1:4074985 C/T cg20703997 chr1:4087676 NA 0.47 5.84 0.46 4.38e-8 Interleukin-17 levels; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg08859206 chr1:53392774 SCP2 0.4 6.1 0.48 1.22e-8 Monocyte count; TGCT cis rs6088580 0.634 rs6059856 chr20:33057954 G/C cg08999081 chr20:33150536 PIGU 0.28 5.67 0.45 9.5e-8 Glomerular filtration rate (creatinine); TGCT cis rs2070433 0.800 rs11702190 chr21:47877367 C/T cg12379764 chr21:47803548 PCNT 0.56 4.79 0.4 4.6e-6 Lymphocyte counts; TGCT cis rs9611565 0.546 rs5758431 chr22:42109917 A/G cg06481639 chr22:41940642 POLR3H 0.71 6.48 0.5 1.95e-9 Vitiligo; TGCT cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg06418219 chr1:154948305 SHC1;CKS1B -0.67 -6.79 -0.52 4.13e-10 Prostate cancer; TGCT cis rs968451 0.526 rs5757617 chr22:39722714 G/C cg17798944 chr22:39715225 SNORD43;RPL3 0.84 9.76 0.66 4.82e-17 Primary biliary cholangitis; TGCT cis rs9325144 0.532 rs1352121 chr12:39130696 A/G cg10518543 chr12:38710700 ALG10B -0.48 -4.44 -0.37 1.97e-5 Morning vs. evening chronotype; TGCT cis rs62380364 0.602 rs606393 chr5:88058163 T/C cg24804195 chr5:87968844 LOC645323 -0.55 -5.34 -0.43 4.23e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg02725872 chr8:58115012 NA -0.39 -4.74 -0.39 5.77e-6 Developmental language disorder (linguistic errors); TGCT trans rs10435719 0.718 rs7813935 chr8:11795636 A/G cg15556689 chr8:8085844 FLJ10661 0.75 7.27 0.55 3.62e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs9611565 0.512 rs45500192 chr22:42177899 A/G cg06634786 chr22:41940651 POLR3H -0.84 -7.83 -0.57 1.91e-12 Vitiligo; TGCT cis rs4073582 0.595 rs474005 chr11:66033301 C/T cg16950941 chr11:66035639 RAB1B 0.58 5.44 0.44 2.67e-7 Gout; TGCT trans rs2727020 0.553 rs7479975 chr11:49581964 C/G cg15704280 chr7:45808275 SEPT13 -0.61 -6.72 -0.52 6.04e-10 Coronary artery disease; TGCT cis rs6840360 0.571 rs7692700 chr4:152552797 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs9381040 0.655 rs2294695 chr6:41036770 A/G cg03526776 chr6:41159608 TREML2 0.25 5.05 0.41 1.52e-6 Alzheimer's disease (late onset); TGCT cis rs7542091 0.669 rs11119357 chr1:210042382 C/T cg21951975 chr1:209979733 IRF6 0.61 6.21 0.49 7.35e-9 Monobrow; TGCT cis rs78456975 1.000 rs11903168 chr2:1560497 C/G cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs1045714 0.895 rs61729413 chr7:2646796 G/A cg17215154 chr7:2644645 IQCE 0.28 4.92 0.4 2.75e-6 Urate levels in lean individuals; TGCT cis rs116161686 0.500 rs76610459 chr1:210050756 T/G cg23283495 chr1:209979779 IRF6 0.61 4.81 0.4 4.3e-6 Coronary artery disease; TGCT cis rs9796 0.621 rs7170049 chr15:41484287 C/A cg18705301 chr15:41695430 NDUFAF1 -0.53 -7.06 -0.54 1.05e-10 Menopause (age at onset); TGCT cis rs2404602 0.716 rs7164813 chr15:76708066 T/C cg26408565 chr15:76604113 ETFA -0.42 -5.43 -0.44 2.8e-7 Blood metabolite levels; TGCT cis rs7829975 0.902 rs777707 chr8:8584344 A/G cg15556689 chr8:8085844 FLJ10661 0.64 5.74 0.46 6.95e-8 Mood instability; TGCT cis rs6582630 0.539 rs8189604 chr12:38308546 G/T cg26384229 chr12:38710491 ALG10B -0.54 -4.72 -0.39 6.38e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs208520 0.874 rs208473 chr6:66917265 G/C cg07460842 chr6:66804631 NA -0.9 -9.16 -0.64 1.34e-15 Exhaled nitric oxide output; TGCT cis rs9549260 0.564 rs4941990 chr13:41299857 A/C cg21288729 chr13:41239152 FOXO1 0.94 9.08 0.63 2.07e-15 Red blood cell count; TGCT cis rs950169 0.881 rs4842852 chr15:84941961 A/G cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT trans rs2760061 0.784 rs1745414 chr1:228212159 T/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.08 -0.54 9.5e-11 Diastolic blood pressure; TGCT cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg13393036 chr8:95962371 TP53INP1 -0.63 -8.66 -0.61 2.14e-14 Type 2 diabetes; TGCT cis rs17384381 0.634 rs11801146 chr1:85915374 C/T cg16011679 chr1:85725395 C1orf52 0.81 6.55 0.51 1.38e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.825 rs497535 chr1:53284677 A/G cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs752010 0.631 rs7515066 chr1:42076915 A/G cg06885757 chr1:42089581 HIVEP3 -0.3 -5.61 -0.45 1.28e-7 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg24675658 chr1:53192096 ZYG11B -0.72 -8.08 -0.59 4.93e-13 Monocyte count; TGCT cis rs10057188 0.868 rs35252676 chr5:77916444 C/T cg07379703 chr5:78279424 ARSB -0.2 -4.53 -0.38 1.34e-5 Pulse pressure; TGCT cis rs10504229 0.679 rs16921606 chr8:58034477 A/C cg25986105 chr8:57232688 SDR16C5 0.5 4.48 0.37 1.7e-5 Developmental language disorder (linguistic errors); TGCT cis rs9486719 0.802 rs2983896 chr6:97029871 G/A cg06623918 chr6:96969491 KIAA0776 -0.95 -8.68 -0.61 1.88e-14 Migraine;Coronary artery disease; TGCT cis rs7104764 1.000 rs2272563 chr11:236871 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs7772486 0.790 rs6924159 chr6:146267873 A/G cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs67072384 1.000 rs7128364 chr11:72451941 A/C cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT trans rs9951602 0.512 rs4798994 chr18:76654327 T/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs11971779 0.941 rs28395455 chr7:139035986 A/G cg07862535 chr7:139043722 LUC7L2 0.65 4.64 0.38 8.61e-6 Diisocyanate-induced asthma; TGCT trans rs6740731 0.518 rs16823846 chr2:145299944 C/T cg19463199 chr3:197401858 MIR922;KIAA0226 0.37 6.77 0.52 4.58e-10 Coronary artery disease; TGCT cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg20607798 chr8:58055168 NA 0.6 4.9 0.4 2.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.74 -0.39 5.77e-6 Prudent dietary pattern; TGCT cis rs523522 0.962 rs651627 chr12:121009198 C/T cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs2230307 0.536 rs575971 chr1:100546591 T/C cg24955406 chr1:100503596 HIAT1 0.72 4.63 0.38 9.24e-6 Carotid intima media thickness; TGCT cis rs13256369 1.000 rs4840351 chr8:8573148 A/G cg17143192 chr8:8559678 CLDN23 0.62 5.82 0.46 4.82e-8 Obesity-related traits; TGCT cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.58 -0.51 1.19e-9 Colorectal cancer; TGCT cis rs2242116 0.896 rs724449 chr3:46935681 C/T cg27129171 chr3:47204927 SETD2 0.61 6.22 0.49 7.1e-9 Birth weight; TGCT cis rs739401 0.572 rs404629 chr11:3077025 A/G cg25174290 chr11:3078921 CARS 0.53 5.06 0.41 1.48e-6 Longevity; TGCT cis rs9611565 0.546 rs132793 chr22:42063681 A/G cg06481639 chr22:41940642 POLR3H 0.73 6.45 0.5 2.21e-9 Vitiligo; TGCT cis rs2249625 0.523 rs2496554 chr6:72855840 A/T cg24401219 chr6:72892597 RIMS1 -0.54 -4.74 -0.39 5.75e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7336332 0.598 rs1885989 chr13:28010117 G/A cg22138327 chr13:27999177 GTF3A 0.81 6.18 0.49 8.63e-9 Weight; TGCT cis rs8064299 0.597 rs9944506 chr17:72782726 C/G cg25054828 chr17:72772726 NAT9;TMEM104 0.91 10.35 0.68 1.8e-18 Monocyte count; TGCT cis rs2188554 0.785 rs172507 chr7:117163047 A/T cg08576598 chr7:116962626 WNT2 0.39 5.23 0.43 7.02e-7 Esophageal adenocarcinoma; TGCT cis rs1797081 1.000 rs780634 chr10:16864327 T/G cg23933602 chr10:16859644 RSU1 1.07 13.89 0.78 5.05e-27 Platelet distribution width; TGCT cis rs8020441 1.000 rs8020441 chr14:51170879 T/G cg04730355 chr14:51134070 SAV1 0.71 5.79 0.46 5.51e-8 Cognitive performance; TGCT cis rs2153535 0.580 rs6912193 chr6:8456306 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs13040088 1.000 rs910831 chr20:61558775 T/C cg23096297 chr20:61557774 DIDO1 1.17 9.71 0.66 6.25e-17 Menopause (age at onset); TGCT cis rs73198271 0.653 rs10087742 chr8:8660474 A/G cg06671706 chr8:8559999 CLDN23 -0.36 -4.61 -0.38 9.98e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2455799 0.573 rs62243672 chr3:15937200 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.61 -0.38 9.69e-6 Mean platelet volume; TGCT cis rs2180341 0.640 rs11154395 chr6:127629138 T/C cg27446573 chr6:127587934 RNF146 0.66 5.85 0.46 4.12e-8 Breast cancer; TGCT cis rs9611565 0.649 rs4822050 chr22:42177453 C/G cg06634786 chr22:41940651 POLR3H -0.77 -7.27 -0.55 3.5e-11 Vitiligo; TGCT cis rs514406 0.621 rs881198 chr1:53196440 C/T cg22166914 chr1:53195759 ZYG11B -0.5 -9.25 -0.64 8.19e-16 Monocyte count; TGCT cis rs7178424 0.616 rs8025282 chr15:62137557 T/C cg00456672 chr15:62358751 C2CD4A -0.31 -4.67 -0.39 7.7e-6 Height; TGCT cis rs9914988 0.887 rs11650282 chr17:27090741 C/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs12449000 1 rs12449000 chr16:89872970 T/C cg21285383 chr16:89894308 SPIRE2 0.45 6.83 0.52 3.35e-10 Schizophrenia; TGCT cis rs617219 0.710 rs2607141 chr5:78558635 G/T cg05890484 chr5:78407552 BHMT 0.34 4.63 0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs739496 0.843 rs630512 chr12:111952167 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.59 0.45 1.4e-7 Platelet count; TGCT cis rs9341808 0.718 rs9361584 chr6:80819946 G/C cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs11098499 0.955 rs7685268 chr4:120162188 G/A cg24670566 chr4:120433619 PDE5A 0.23 4.45 0.37 1.89e-5 Corneal astigmatism; TGCT cis rs2997447 0.655 rs2275949 chr1:26385150 C/G cg19759804 chr1:25889155 LDLRAP1 0.32 4.52 0.38 1.45e-5 QRS complex (12-leadsum); TGCT cis rs6723226 0.721 rs3769600 chr2:32616879 G/A cg02381751 chr2:32503542 YIPF4 -0.45 -4.47 -0.37 1.77e-5 Intelligence (multi-trait analysis); TGCT cis rs896854 0.654 rs13281625 chr8:95972738 T/C cg16049864 chr8:95962084 TP53INP1 -0.75 -10.47 -0.69 9.05e-19 Type 2 diabetes; TGCT cis rs1448094 0.654 rs7133797 chr12:86294184 G/C cg00310523 chr12:86230176 RASSF9 0.31 4.5 0.37 1.56e-5 Major depressive disorder; TGCT cis rs17001868 0.568 rs9611315 chr22:40736900 A/T cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs9300255 0.596 rs1727331 chr12:123718879 C/G cg00376283 chr12:123451042 ABCB9 -0.75 -6.4 -0.5 2.89e-9 Neutrophil percentage of white cells; TGCT cis rs514406 0.505 rs856721 chr1:53162156 C/A cg22166914 chr1:53195759 ZYG11B 0.44 7.64 0.57 5.13e-12 Monocyte count; TGCT cis rs8180040 0.729 rs11720439 chr3:47347003 T/G cg27129171 chr3:47204927 SETD2 -0.6 -6.53 -0.51 1.5e-9 Colorectal cancer; TGCT cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg03303774 chr4:1407052 NA -0.3 -4.69 -0.39 7.16e-6 Obesity-related traits; TGCT cis rs1670533 0.697 rs658846 chr4:1084723 G/C cg20887711 chr4:1340912 KIAA1530 0.74 5.62 0.45 1.21e-7 Recombination rate (females); TGCT trans rs9329221 0.741 rs55975067 chr8:9806824 C/G cg15556689 chr8:8085844 FLJ10661 -0.81 -7.5 -0.56 1.07e-11 Neuroticism; TGCT cis rs2072499 0.966 rs2984615 chr1:156165317 G/C cg06970220 chr1:156163860 SLC25A44 0.73 6.46 0.5 2.13e-9 Testicular germ cell tumor; TGCT cis rs9916302 0.904 rs2338800 chr17:37498149 C/G cg15445000 chr17:37608096 MED1 -0.33 -4.88 -0.4 3.25e-6 Glomerular filtration rate (creatinine); TGCT trans rs7618501 0.540 rs11130241 chr3:50131459 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.89 -10.03 -0.67 1.1e-17 Intelligence (multi-trait analysis); TGCT cis rs9486719 0.948 rs11152970 chr6:96909077 A/G cg18709589 chr6:96969512 KIAA0776 -0.68 -5.05 -0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs7172809 0.897 rs74026933 chr15:77826969 A/C cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs9926296 0.744 rs6860 chr16:89711120 C/T cg04287289 chr16:89883240 FANCA -0.54 -4.91 -0.4 2.83e-6 Vitiligo; TGCT cis rs858239 0.601 rs3735228 chr7:23170427 T/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.28 -0.43 5.64e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2404602 0.692 rs55729975 chr15:76803226 G/A cg26408565 chr15:76604113 ETFA -0.36 -4.65 -0.39 8.27e-6 Blood metabolite levels; TGCT cis rs7216064 1.000 rs2052187 chr17:65834737 T/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.82 -0.52 3.54e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7027203 0.759 rs10761282 chr9:96586175 G/A cg14598338 chr9:96623480 NA -0.61 -9.21 -0.64 1.03e-15 DNA methylation (variation); TGCT cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.53 4.63 0.38 9.19e-6 Height; TGCT cis rs7552404 1.000 rs12123977 chr1:76209754 A/G cg03433033 chr1:76189801 ACADM -0.99 -8.26 -0.6 1.87e-13 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9818758 0.607 rs5030795 chr3:49141116 C/T cg07636037 chr3:49044803 WDR6 -0.94 -5.17 -0.42 9.04e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7104764 1.000 rs6598066 chr11:243185 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.1 10.98 0.7 5.33e-20 Menarche (age at onset); TGCT cis rs11098499 0.865 rs2389809 chr4:120377399 T/C cg09307838 chr4:120376055 NA 0.71 6.98 0.53 1.57e-10 Corneal astigmatism; TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs617219 0.659 rs13182512 chr5:78573790 A/T cg05890484 chr5:78407552 BHMT -0.34 -4.63 -0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9948 0.786 rs62152775 chr2:97448474 G/T cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs6450176 0.909 rs6866586 chr5:53295568 A/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7172809 0.573 rs7182221 chr15:77589535 C/T cg22256960 chr15:77711686 NA 0.47 4.63 0.38 9.08e-6 Glucose homeostasis traits; TGCT cis rs727563 0.555 rs5751136 chr22:42075581 T/A cg03806693 chr22:41940476 POLR3H 1.08 11.5 0.72 2.85e-21 Crohn's disease;Inflammatory bowel disease; TGCT cis rs514406 0.861 rs35517489 chr1:53304062 G/C cg01802117 chr1:53393560 SCP2 -0.42 -4.95 -0.41 2.36e-6 Monocyte count; TGCT cis rs6951245 1.000 rs2363286 chr7:1091625 A/G cg18402987 chr7:1209562 NA 0.61 5.52 0.44 1.88e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611519 0.964 rs2092563 chr22:41592677 G/A cg03806693 chr22:41940476 POLR3H -0.68 -6.28 -0.49 5.17e-9 Neuroticism; TGCT cis rs35934224 0.783 rs58714937 chr22:19856710 C/T cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT cis rs3749237 1.000 rs3749237 chr3:49770032 C/T cg10152585 chr3:50297680 NA 0.5 4.65 0.39 8.38e-6 Resting heart rate; TGCT cis rs593982 0.920 rs618456 chr11:65475620 C/T cg08755490 chr11:65554678 OVOL1 1.3 7.59 0.56 6.8e-12 Atopic dermatitis; TGCT cis rs3008870 1.000 rs2815361 chr1:67494591 G/T cg08660285 chr1:67390436 MIER1;WDR78 1.05 11.01 0.7 4.47e-20 Lymphocyte percentage of white cells; TGCT cis rs9916302 0.904 rs2338798 chr17:37547269 T/C cg15445000 chr17:37608096 MED1 -0.33 -4.7 -0.39 6.85e-6 Glomerular filtration rate (creatinine); TGCT trans rs7618501 0.602 rs2071206 chr3:50160109 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT trans rs208515 0.525 rs10498841 chr6:66663706 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.9 9.56 0.65 1.46e-16 Exhaled nitric oxide levels; TGCT cis rs1799949 1.000 rs2070834 chr17:41242285 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.79e-7 Menopause (age at onset); TGCT cis rs752092 1.000 rs752092 chr15:101781934 C/T cg25114630 chr15:101792522 CHSY1 -0.59 -5.76 -0.46 6.3e-8 Corneal structure; TGCT cis rs12497850 1.000 rs12497850 chr3:48748989 G/T cg07636037 chr3:49044803 WDR6 0.92 10.34 0.68 1.91e-18 Parkinson's disease; TGCT cis rs4517514 0.509 rs12417652 chr11:89905239 T/G cg05041596 chr11:89867385 NAALAD2 0.56 5.23 0.43 6.94e-7 Trans fatty acid levels; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg25767906 chr1:53392781 SCP2 -0.59 -7.58 -0.56 7.1e-12 Monocyte count; TGCT cis rs79349575 0.679 rs9894239 chr17:46997959 C/T cg07967210 chr17:47022446 SNF8 -0.41 -5.44 -0.44 2.69e-7 Type 2 diabetes; TGCT cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.6 5.09 0.42 1.29e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs6089829 0.962 rs6062393 chr20:61663230 G/A cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs7584330 0.744 rs10929235 chr2:238380272 A/G cg14458575 chr2:238380390 NA 0.6 9.0 0.63 3.2e-15 Prostate cancer; TGCT cis rs597539 0.654 rs619727 chr11:68627535 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs79057730 0.684 rs6955004 chr7:790792 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.69 6.62 0.51 9.78e-10 Initial pursuit acceleration; TGCT cis rs7208859 0.623 rs28556733 chr17:29083945 T/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs8177253 0.898 rs8177258 chr3:133480387 C/A cg08048268 chr3:133502702 NA -0.65 -9.84 -0.66 3.1e-17 Iron status biomarkers; TGCT cis rs7666738 0.822 rs17484018 chr4:98988960 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg22764044 chr5:178986830 RUFY1 0.44 4.75 0.39 5.42e-6 Lung cancer; TGCT cis rs9611565 0.580 rs5758449 chr22:42140160 C/T cg06481639 chr22:41940642 POLR3H 0.54 4.57 0.38 1.17e-5 Vitiligo; TGCT cis rs4689592 0.513 rs3857178 chr4:7066516 G/A cg06697600 chr4:7070879 GRPEL1 -0.47 -4.94 -0.41 2.42e-6 Monocyte percentage of white cells; TGCT trans rs7618501 0.573 rs2624824 chr3:50088266 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.5 -0.65 2.02e-16 Intelligence (multi-trait analysis); TGCT cis rs806215 0.526 rs2402871 chr7:127439519 G/A cg11539674 chr7:127291444 SND1 -0.37 -4.72 -0.39 6.35e-6 Type 2 diabetes; TGCT cis rs11105298 0.891 rs4842662 chr12:89933446 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.85 -0.4 3.63e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs916888 0.610 rs199454 chr17:44800110 G/A cg16520312 chr17:43971471 MAPT;LOC100128977 0.46 4.52 0.38 1.44e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12286929 0.933 rs11215381 chr11:115022233 T/C cg04017736 chr11:115827165 NA -0.2 -4.71 -0.39 6.44e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs72717009 0.825 rs7529425 chr1:161479599 G/A cg23840854 chr1:161414152 NA -1.02 -6.12 -0.48 1.12e-8 Rheumatoid arthritis; TGCT cis rs11190604 1.000 rs2495732 chr10:102357780 T/C cg16342193 chr10:102329863 NA -0.44 -5.38 -0.44 3.57e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12220238 0.915 rs75467340 chr10:75907318 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.91 6.77 0.52 4.61e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2576037 0.583 rs501882 chr18:44411066 A/T cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.68 -0.39 7.48e-6 Personality dimensions; TGCT cis rs2282802 0.685 rs6870103 chr5:139692515 G/T cg01081189 chr5:139537190 NA -0.27 -5.04 -0.41 1.6e-6 Intelligence (multi-trait analysis); TGCT cis rs1903068 0.853 rs9312655 chr4:56002665 T/C cg09978860 chr4:56023921 NA 0.56 6.34 0.49 3.88e-9 Endometriosis; TGCT cis rs12643440 0.538 rs66857912 chr4:17146347 T/C cg22650099 chr4:17144496 NA -0.49 -5.03 -0.41 1.66e-6 Metabolite levels (Pyroglutamine); TGCT cis rs1691799 0.867 rs961049 chr12:66762591 A/C cg16791601 chr12:66731901 HELB 0.27 5.82 0.46 4.7e-8 White blood cell count (basophil); TGCT cis rs4689388 0.926 rs4689394 chr4:6291003 C/G cg14416269 chr4:6271139 WFS1 -0.38 -5.11 -0.42 1.19e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9649213 0.614 rs10953254 chr7:97914305 A/G cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.7 -0.62 1.72e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs13242816 1.000 rs3807988 chr7:116180735 A/C cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs9611565 0.592 rs5996037 chr22:41965292 A/G cg13695892 chr22:41940480 POLR3H -0.87 -8.17 -0.59 2.95e-13 Vitiligo; TGCT cis rs2562456 0.876 rs62110163 chr19:21728822 G/A cg01304269 chr19:21688519 ZNF429 0.57 4.74 0.39 5.86e-6 Pain; TGCT cis rs6674176 1.000 rs6674176 chr1:44379957 G/A cg12908607 chr1:44402522 ARTN -0.74 -8.71 -0.62 1.58e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg16414030 chr3:133502952 NA -0.5 -7.01 -0.53 1.39e-10 Iron status biomarkers; TGCT cis rs11112613 0.762 rs73184078 chr12:105950017 A/G cg03607813 chr12:105948248 NA 0.52 6.0 0.47 2.03e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT trans rs1814175 0.534 rs1983448 chr11:49933856 C/A cg11707556 chr5:10655725 ANKRD33B -0.42 -9.87 -0.66 2.56e-17 Height; TGCT cis rs7586879 0.616 rs6545813 chr2:25131287 C/T cg01884057 chr2:25150051 NA 0.36 7.1 0.54 8.43e-11 Body mass index; TGCT cis rs853679 0.517 rs6932109 chr6:28078303 A/G cg12963246 chr6:28129442 ZNF389 -0.52 -5.1 -0.42 1.23e-6 Depression; TGCT cis rs1008375 1.000 rs10805359 chr4:17684886 A/G cg18681998 chr4:17616180 MED28 0.92 10.46 0.68 9.72e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs881375 0.678 rs10818488 chr9:123705087 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.09 0.42 1.27e-6 Rheumatoid arthritis; TGCT cis rs6952808 0.862 rs4721167 chr7:1933224 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.74 -0.46 6.77e-8 Bipolar disorder and schizophrenia; TGCT cis rs2371030 1.000 rs1019393 chr2:211593081 C/G cg18417063 chr2:211583084 NA -0.31 -4.45 -0.37 1.91e-5 Non-small cell lung cancer; TGCT cis rs7772486 0.754 rs702304 chr6:145990797 A/G cg05347473 chr6:146136440 FBXO30 -0.53 -4.97 -0.41 2.18e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs881375 1.000 rs6478484 chr9:123652380 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.44 0.37 1.95e-5 Rheumatoid arthritis; TGCT cis rs12220238 0.730 rs11000899 chr10:75913055 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs9929218 0.953 rs34909703 chr16:68740097 T/C cg01251360 chr16:68772225 CDH1 0.29 4.7 0.39 6.75e-6 Colorectal cancer; TGCT cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg03264133 chr6:25882463 NA -0.7 -6.47 -0.5 2.03e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.570 rs1921415 chr4:99093804 C/T cg17366294 chr4:99064904 C4orf37 0.58 5.38 0.43 3.6e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2820315 1.000 rs2644112 chr1:201806106 T/C cg12730843 chr1:201915899 LMOD1 -0.26 -4.72 -0.39 6.26e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2637266 1.000 rs11001830 chr10:78346396 G/A cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT cis rs4253772 0.550 rs6007779 chr22:46678615 A/C cg09491104 chr22:46646882 C22orf40 -0.56 -4.52 -0.38 1.44e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs7727544 0.716 rs2089855 chr5:131573529 A/G cg24060327 chr5:131705240 SLC22A5 -0.6 -5.67 -0.45 9.52e-8 Blood metabolite levels; TGCT cis rs433852 0.718 rs550455 chr19:49136515 A/G cg07996880 chr19:49339085 HSD17B14 -0.29 -4.88 -0.4 3.16e-6 Elevated serum carcinoembryonic antigen levels;Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs9810089 0.814 rs866758 chr3:136117870 G/C cg12473912 chr3:136751656 NA 0.36 5.04 0.41 1.58e-6 Gestational age at birth (child effect); TGCT cis rs6700896 0.522 rs6588156 chr1:66160433 A/G cg14976592 chr1:65886160 LEPROT;LEPR -0.54 -4.44 -0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2243480 1.000 rs13237037 chr7:65997882 T/C cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs6087771 0.642 rs6060411 chr20:30222139 T/C cg13852791 chr20:30311386 BCL2L1 0.77 6.53 0.51 1.51e-9 Subcortical brain region volumes;Putamen volume; TGCT cis rs2730245 0.505 rs2657360 chr7:158673604 A/G cg11984989 chr7:158649758 WDR60 1.02 9.51 0.65 1.95e-16 Height; TGCT cis rs7552404 0.691 rs1770890 chr1:76401117 A/G cg22875332 chr1:76189707 ACADM -0.66 -6.78 -0.52 4.38e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7943191 0.810 rs7942154 chr11:62337163 G/A cg13298116 chr11:62369859 EML3;MTA2 0.59 7.16 0.54 6.26e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs2742417 1.000 rs2742432 chr3:45737467 G/T cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs116095464 0.558 rs7713524 chr5:276200 C/T cg22857025 chr5:266934 NA 0.37 6.26 0.49 5.78e-9 Breast cancer; TGCT cis rs858239 0.600 rs7776649 chr7:23119317 C/T cg05602783 chr7:23145260 KLHL7 -0.64 -5.28 -0.43 5.69e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9291683 0.632 rs13137074 chr4:10042842 C/T cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.29e-14 Bone mineral density; TGCT cis rs4700695 0.719 rs27046 chr5:65439964 G/C cg21114390 chr5:65439923 SFRS12 -0.84 -7.36 -0.55 2.26e-11 Facial morphology (factor 19); TGCT cis rs2888674 1.000 rs717658 chr7:150503637 A/T cg10409299 chr7:150498843 TMEM176B;TMEM176A 0.28 4.76 0.39 5.29e-6 Forced expiratory volume in 1 second (occupational environmental exposures interaction); TGCT cis rs682748 0.810 rs62349989 chr5:17111970 A/T cg23987134 chr5:17158319 LOC285696 -0.21 -4.96 -0.41 2.31e-6 Hippocampal atrophy; TGCT cis rs2832191 0.791 rs2832181 chr21:30481371 G/T cg08807101 chr21:30365312 RNF160 -0.66 -6.19 -0.49 8.16e-9 Dental caries; TGCT cis rs138249 0.867 rs715616 chr22:50558505 G/A cg24864161 chr22:50528282 MOV10L1 0.47 5.02 0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs7646881 0.504 rs61080878 chr3:158462897 C/T cg18349298 chr3:158450550 RARRES1 0.42 4.44 0.37 1.97e-5 Tetralogy of Fallot; TGCT cis rs2895526 0.691 rs10752269 chr10:12692902 G/A cg18283737 chr10:12085149 UPF2 0.48 4.62 0.38 9.47e-6 Headache; TGCT cis rs7208859 0.623 rs7208441 chr17:29143863 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7191439 0.789 rs4433802 chr16:88784964 A/G cg27087555 chr16:88793112 FAM38A -0.55 -5.9 -0.47 3.18e-8 Plateletcrit; TGCT trans rs61931739 0.500 rs7977186 chr12:34431486 C/G cg26384229 chr12:38710491 ALG10B 0.72 6.8 0.52 4.02e-10 Morning vs. evening chronotype; TGCT cis rs9902453 0.838 rs8064689 chr17:28217053 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 7.07 0.54 9.76e-11 Coffee consumption (cups per day); TGCT cis rs308403 0.608 rs309362 chr4:123658154 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.72 6.85 0.52 3.1e-10 Blood protein levels; TGCT cis rs7666738 0.791 rs7377018 chr4:99034962 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs8077889 0.956 rs61608877 chr17:41848713 A/C cg26893861 chr17:41843967 DUSP3 1.09 13.68 0.78 1.57e-26 Triglycerides; TGCT cis rs185694 0.817 rs1952607 chr13:30888981 A/G cg07600127 chr13:30881527 KATNAL1 0.61 5.19 0.42 8.26e-7 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs6582630 0.555 rs35186318 chr12:38295822 C/T cg26384229 chr12:38710491 ALG10B -0.55 -4.75 -0.39 5.58e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4824093 0.610 rs12106611 chr22:50242686 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.45 4.65 0.39 8.43e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs35306767 0.715 rs1871622 chr10:1049309 T/G cg18964960 chr10:1102726 WDR37 0.78 5.46 0.44 2.45e-7 Eosinophil percentage of granulocytes; TGCT cis rs886126 0.950 rs2097658 chr12:111690466 C/T cg10833066 chr12:111807467 FAM109A 0.33 5.64 0.45 1.07e-7 Coronary heart disease; TGCT cis rs2842992 0.872 rs2758330 chr6:160104844 G/T cg11366901 chr6:160182831 ACAT2 0.94 6.18 0.49 8.48e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs9611565 0.512 rs6519289 chr22:42170432 A/C cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs11105298 0.685 rs117578503 chr12:89836672 G/C cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6121246 0.609 rs6089075 chr20:30392884 A/G cg13852791 chr20:30311386 BCL2L1 0.81 7.58 0.56 7.06e-12 Mean corpuscular hemoglobin; TGCT cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.78 -6.92 -0.53 2.16e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12971120 0.891 rs12608037 chr18:72169395 A/G cg25817165 chr18:72167213 CNDP2 -0.29 -5.11 -0.42 1.16e-6 Refractive error; TGCT cis rs8177253 0.965 rs8177245 chr3:133479230 A/G cg08439880 chr3:133502540 NA -0.31 -5.87 -0.47 3.69e-8 Iron status biomarkers; TGCT cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg25036284 chr2:26402008 FAM59B -0.66 -5.34 -0.43 4.22e-7 Gut microbiome composition (summer); TGCT cis rs12368653 0.545 rs2277324 chr12:58013175 G/A cg12615879 chr12:58013172 SLC26A10 0.63 7.5 0.56 1.05e-11 Multiple sclerosis; TGCT cis rs9787249 0.957 rs1046988 chr1:40219065 A/G cg24920358 chr1:40204285 PPIE -0.54 -9.82 -0.66 3.37e-17 Blood protein levels; TGCT cis rs10504229 1.000 rs72652906 chr8:58188360 C/A cg24829409 chr8:58192753 C8orf71 -0.57 -5.35 -0.43 4.03e-7 Developmental language disorder (linguistic errors); TGCT cis rs7833790 0.724 rs6473310 chr8:82707981 A/G cg23324259 chr8:82754387 SNX16 -0.62 -4.88 -0.4 3.19e-6 Diastolic blood pressure; TGCT cis rs7412746 0.611 rs11803940 chr1:150685835 A/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Melanoma; TGCT cis rs3733585 0.699 rs28837683 chr4:9959808 C/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.55 -0.51 1.41e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4285028 0.580 rs2293611 chr3:121643163 G/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.61 -5.22 -0.42 7.38e-7 Multiple sclerosis; TGCT cis rs2404602 0.716 rs12592171 chr15:76755133 G/C cg22467129 chr15:76604101 ETFA -0.57 -6.83 -0.52 3.31e-10 Blood metabolite levels; TGCT cis rs10851411 0.779 rs3742997 chr15:42729286 T/A cg23803468 chr15:43513504 EPB42 0.26 5.08 0.42 1.32e-6 Glucose homeostasis traits; TGCT trans rs1005277 0.579 rs116912400 chr10:38479207 G/T cg17830980 chr10:43048298 ZNF37B -0.84 -10.46 -0.68 9.38e-19 Extrinsic epigenetic age acceleration; TGCT cis rs2629540 0.889 rs10901815 chr10:126435598 G/A cg08799069 chr10:126477246 METTL10 -0.3 -4.5 -0.37 1.54e-5 Cocaine dependence; TGCT cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6074578 0.679 rs12480299 chr20:140171 A/G cg16931068 chr20:139680 DEFB127 0.27 4.64 0.38 8.57e-6 Hirschsprung disease; TGCT cis rs1483890 0.723 rs12631128 chr3:69411416 G/T cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.43 4.84 0.4 3.75e-6 Lymphocyte counts; TGCT cis rs9443645 0.838 rs946022 chr6:79672133 G/T cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs5750830 0.649 rs5750808 chr22:39790987 G/A cg24399712 chr22:39784796 NA -1.06 -12.55 -0.75 8.19e-24 Intelligence (multi-trait analysis); TGCT cis rs13401104 0.587 rs62190973 chr2:237145231 T/A cg26422059 chr2:237146110 ASB18 0.57 4.56 0.38 1.19e-5 Educational attainment; TGCT cis rs12220238 0.915 rs11001003 chr10:76099944 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.88 5.86 0.47 3.87e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs10782582 0.609 rs5745430 chr1:76332994 C/T cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs116095464 0.558 rs6866776 chr5:264495 C/T cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg22618164 chr12:122356400 WDR66 0.59 6.03 0.48 1.71e-8 Mean corpuscular volume; TGCT cis rs2456568 0.778 rs2456563 chr11:93678675 C/T cg26875233 chr11:93583750 C11orf90 -0.41 -5.18 -0.42 8.79e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2197308 0.610 rs10880837 chr12:37864924 C/T cg13010199 chr12:38710504 ALG10B 0.64 5.0 0.41 1.87e-6 Morning vs. evening chronotype; TGCT cis rs1862618 0.641 rs170733 chr5:56249251 A/G cg12311346 chr5:56204834 C5orf35 0.56 5.93 0.47 2.82e-8 Initial pursuit acceleration; TGCT cis rs7586879 0.520 rs6718511 chr2:25122324 A/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs13191362 1.000 rs34725898 chr6:163127302 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.17 0.59 3.08e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28386778 0.966 rs2854206 chr17:61947203 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.33 0.43 4.5e-7 Prudent dietary pattern; TGCT cis rs763121 0.706 rs3827356 chr22:39064806 G/T cg06022373 chr22:39101656 GTPBP1 -0.73 -7.29 -0.55 3.19e-11 Menopause (age at onset); TGCT cis rs7582180 0.629 rs11686799 chr2:100956055 C/G cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs12134245 0.874 rs35115044 chr1:92021650 A/G cg25838465 chr1:92012736 NA -0.34 -5.64 -0.45 1.08e-7 Breast cancer; TGCT cis rs3617 0.625 rs11719137 chr3:52876389 G/T cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6701037 0.566 rs10489326 chr1:175134677 A/G cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs7666738 0.606 rs6852813 chr4:99084671 G/A cg17366294 chr4:99064904 C4orf37 0.57 5.34 0.43 4.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11785400 0.963 rs4579507 chr8:143733663 C/G cg10596483 chr8:143751796 JRK 0.55 6.01 0.47 1.93e-8 Schizophrenia; TGCT cis rs2439831 0.867 rs8041132 chr15:43635136 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT trans rs1814175 0.746 rs10839429 chr11:49906845 G/A cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs1461503 0.934 rs7113330 chr11:122843358 C/T cg27398637 chr11:122830231 C11orf63 -0.39 -4.75 -0.39 5.58e-6 Menarche (age at onset); TGCT trans rs1005277 0.505 rs200931 chr10:38128434 A/C cg17830980 chr10:43048298 ZNF37B -0.73 -8.06 -0.59 5.35e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7267979 1.000 rs2482943 chr20:25380593 G/A cg16686733 chr20:25566563 NINL -0.59 -6.05 -0.48 1.57e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2836950 0.545 rs8132424 chr21:40584412 A/T cg06238570 chr21:40685208 BRWD1 0.62 6.6 0.51 1.07e-9 Menarche (age at onset); TGCT cis rs7474896 0.583 rs10827818 chr10:38000856 T/C cg13720705 chr10:37990370 NA 0.34 4.9 0.4 2.9e-6 Obesity (extreme); TGCT cis rs2201728 0.967 rs2173199 chr4:100171379 G/A cg07219303 chr4:100140905 ADH6 -0.35 -5.2 -0.42 8.15e-7 Cardiac Troponin-T levels; TGCT cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs910316 1.000 rs28626045 chr14:75589195 G/C cg08847533 chr14:75593920 NEK9 0.95 10.91 0.7 7.73e-20 Height; TGCT cis rs7267979 0.868 rs6138550 chr20:25223430 C/T cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6460942 0.915 rs10488158 chr7:12508894 C/T cg06484146 chr7:12443880 VWDE -0.6 -5.33 -0.43 4.49e-7 Coronary artery disease; TGCT cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg03517284 chr6:25882590 NA 0.52 5.14 0.42 1.05e-6 Blood metabolite levels; TGCT cis rs1371867 0.846 rs1788181 chr8:101334068 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs9660180 0.780 rs12038111 chr1:1703849 T/C cg23982607 chr1:1823379 GNB1 -0.55 -8.56 -0.61 3.69e-14 Body mass index; TGCT cis rs9913156 0.841 rs56239958 chr17:4600280 G/C cg00122941 chr17:4613640 ARRB2 0.88 7.63 0.57 5.46e-12 Lymphocyte counts; TGCT cis rs6089829 0.888 rs4809468 chr20:61673566 T/C cg02380750 chr20:61661411 NA 0.35 5.76 0.46 6.25e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs6750047 0.719 rs100489 chr2:38266478 T/C cg07380506 chr2:38303506 CYP1B1 -0.56 -5.04 -0.41 1.62e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs4953076 0.573 rs6738023 chr2:44405931 T/C cg04920474 chr2:44395004 PPM1B 0.58 5.75 0.46 6.43e-8 Height; TGCT cis rs7829975 0.572 rs28446104 chr8:8795901 C/G cg06636001 chr8:8085503 FLJ10661 -0.76 -6.67 -0.51 7.48e-10 Mood instability; TGCT cis rs3845702 1.000 rs3845702 chr2:180848488 A/C cg01881094 chr2:180872142 CWC22 0.65 5.97 0.47 2.31e-8 Schizophrenia; TGCT cis rs7772486 0.846 rs9373482 chr6:146363123 A/C cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg04267008 chr7:1944627 MAD1L1 -0.4 -5.24 -0.43 6.74e-7 Bipolar disorder and schizophrenia; TGCT cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6598955 0.671 rs7550997 chr1:26596080 G/A cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs6088580 0.634 rs6059905 chr20:33126946 T/C cg06115741 chr20:33292138 TP53INP2 0.55 4.83 0.4 3.91e-6 Glomerular filtration rate (creatinine); TGCT trans rs7613875 0.580 rs2624819 chr3:50010571 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.83 8.65 0.61 2.29e-14 Body mass index; TGCT cis rs4664308 0.967 rs56293836 chr2:160910958 T/C cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs9513593 1.000 rs9300540 chr13:100018225 T/A cg21788972 chr13:99853209 UBAC2 0.56 4.45 0.37 1.92e-5 Psoriasis; TGCT cis rs922182 0.617 rs13329183 chr15:64240809 A/G cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.33e-10 Blood protein levels; TGCT cis rs796364 0.865 rs769948 chr2:200728475 C/A cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs72627509 0.638 rs73165963 chr4:57740536 A/G cg26694713 chr4:57773883 REST 0.82 6.68 0.51 7.07e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs826838 0.651 rs12367384 chr12:38618460 G/T cg26384229 chr12:38710491 ALG10B 0.65 6.07 0.48 1.44e-8 Heart rate; TGCT cis rs12681288 0.862 rs4735981 chr8:1018437 A/C cg06709756 chr8:1339049 NA -0.23 -4.47 -0.37 1.75e-5 Schizophrenia; TGCT cis rs8129326 0.934 rs7279041 chr21:35804585 C/T cg27150370 chr21:34863940 DNAJC28 -0.46 -4.56 -0.38 1.2e-5 Cancer; TGCT cis rs4455778 0.580 rs59806378 chr7:49129934 T/A cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs7666738 0.830 rs17558193 chr4:99049593 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs4334758 chr4:98971875 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg16325326 chr1:53192061 ZYG11B 0.59 6.79 0.52 4.22e-10 Monocyte count; TGCT cis rs1005277 0.579 rs1780116 chr10:38526621 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.36 -0.6 1.05e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1799949 0.929 rs799906 chr17:41278116 T/C cg23758822 chr17:41437982 NA 0.68 6.78 0.52 4.4e-10 Menopause (age at onset); TGCT cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7267979 1.000 rs4815404 chr20:25301845 T/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9929218 0.501 rs12448999 chr16:68815549 T/A cg01251360 chr16:68772225 CDH1 -0.25 -4.51 -0.38 1.51e-5 Colorectal cancer; TGCT cis rs11642862 1.000 rs11645367 chr16:30770074 C/T cg02466173 chr16:30829666 NA -0.39 -4.68 -0.39 7.24e-6 Tonsillectomy; TGCT cis rs2072499 0.778 rs2842868 chr1:156196407 A/C cg25208724 chr1:156163844 SLC25A44 0.92 8.45 0.6 6.47e-14 Testicular germ cell tumor; TGCT cis rs10782582 0.609 rs5745410 chr1:76314356 C/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs2760061 0.819 rs1745417 chr1:228204279 C/T cg02753203 chr1:228287806 NA 0.32 6.14 0.48 1e-8 Diastolic blood pressure; TGCT cis rs1997103 1.000 rs6954474 chr7:55404847 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg11965913 chr1:205819406 PM20D1 0.6 9.21 0.64 1.03e-15 Menarche (age at onset); TGCT cis rs9322193 0.884 rs11155679 chr6:150080017 T/C cg13206674 chr6:150067644 NUP43 0.54 4.65 0.39 8.48e-6 Lung cancer; TGCT cis rs6089584 0.821 rs2273990 chr20:60579149 G/T cg13770153 chr20:60521292 NA -0.54 -7.29 -0.55 3.23e-11 Body mass index; TGCT cis rs881375 0.967 rs7034653 chr9:123687372 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.02 0.41 1.72e-6 Rheumatoid arthritis; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs514406 0.505 rs425520 chr1:53179805 C/G cg25767906 chr1:53392781 SCP2 -0.47 -5.35 -0.43 4.15e-7 Monocyte count; TGCT cis rs4383453 0.539 rs4678014 chr3:123100170 A/G cg04890266 chr3:123102914 ADCY5 -0.5 -8.19 -0.59 2.68e-13 Gestational age at birth (maternal effect); TGCT cis rs7678296 0.649 rs73128366 chr4:37241908 T/C cg06805348 chr4:37245195 KIAA1239 0.57 4.83 0.4 3.87e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs9291683 0.546 rs4529049 chr4:10045389 C/T cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Bone mineral density; TGCT cis rs4523957 0.552 rs923862 chr17:2031382 A/C cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11650494 0.803 rs117801358 chr17:47447950 C/A cg08112188 chr17:47440006 ZNF652 1.04 5.31 0.43 4.85e-7 Prostate cancer; TGCT cis rs986417 0.901 rs7160405 chr14:60970004 G/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs3020736 0.500 rs2413669 chr22:42507748 A/C cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs1496653 0.602 rs35975795 chr3:23417996 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs3008870 0.920 rs3008865 chr1:67402838 T/C cg03991309 chr1:68237761 GNG12 0.27 4.55 0.38 1.26e-5 Lymphocyte percentage of white cells; TGCT cis rs7178572 0.539 rs16968809 chr15:77672118 C/T cg15453836 chr15:77711506 NA 0.46 5.09 0.42 1.29e-6 Type 2 diabetes; TGCT cis rs17122693 0.681 rs72679587 chr14:51092686 A/G cg04730355 chr14:51134070 SAV1 1.24 8.74 0.62 1.38e-14 Cognitive performance; TGCT cis rs910316 1.000 rs910316 chr14:75626042 A/C cg08847533 chr14:75593920 NEK9 0.94 10.45 0.68 1.01e-18 Height; TGCT cis rs40363 1.000 rs37767 chr16:3514962 C/T cg00484396 chr16:3507460 NAT15 0.44 5.08 0.41 1.36e-6 Tuberculosis; TGCT cis rs78487399 0.808 rs6544669 chr2:43736171 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.84 -0.4 3.79e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1799949 0.929 rs4792988 chr17:41437547 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.17 0.42 9.27e-7 Menopause (age at onset); TGCT cis rs28374715 0.635 rs28557159 chr15:41657353 T/C cg18705301 chr15:41695430 NDUFAF1 -0.88 -14.1 -0.78 1.56e-27 Ulcerative colitis; TGCT cis rs7296418 0.885 rs1051434 chr12:123641200 C/T cg00376283 chr12:123451042 ABCB9 0.84 7.66 0.57 4.68e-12 Platelet count; TGCT cis rs853679 0.517 rs4713148 chr6:28115921 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs10929159 0.964 rs3754659 chr2:236950634 C/T cg16852440 chr2:237570117 NA -0.29 -4.64 -0.38 8.8e-6 Parkinson's disease; TGCT cis rs1784581 0.802 rs7768986 chr6:162427890 G/C cg17173639 chr6:162384350 PARK2 0.42 7.38 0.55 2.03e-11 Itch intensity from mosquito bite; TGCT cis rs9894429 0.538 rs9747080 chr17:79606704 A/G cg18240062 chr17:79603768 NPLOC4 0.75 7.08 0.54 9.3e-11 Eye color traits; TGCT cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs769267 0.930 rs892022 chr19:19613381 G/A cg03709012 chr19:19516395 GATAD2A 0.74 6.22 0.49 7.04e-9 Tonsillectomy; TGCT cis rs9916302 0.718 rs10445306 chr17:37591422 A/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.81 -0.4 4.27e-6 Glomerular filtration rate (creatinine); TGCT trans rs916888 0.610 rs199452 chr17:44801340 C/T cg01341218 chr17:43662625 NA 0.84 7.62 0.56 5.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2228479 0.867 rs57492102 chr16:89975572 A/G cg06558623 chr16:89946397 TCF25 0.53 6.48 0.5 1.99e-9 Skin colour saturation; TGCT cis rs6693567 0.507 rs4970964 chr1:150458029 A/G cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Migraine; TGCT cis rs12286929 0.637 rs7125361 chr11:115080042 C/G cg04017736 chr11:115827165 NA -0.19 -4.64 -0.38 8.84e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs478304 0.593 rs6591188 chr11:65467953 T/C cg17480646 chr11:65405466 SIPA1 -0.63 -8.43 -0.6 7.5e-14 Acne (severe); TGCT cis rs634534 0.622 rs531612 chr11:65705432 C/T cg17985854 chr11:65770987 BANF1;EIF1AD -0.22 -4.91 -0.4 2.75e-6 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7973719 0.966 rs7310539 chr12:7329996 C/G cg07052231 chr12:7363540 PEX5 0.34 5.16 0.42 9.34e-7 IgG glycosylation; TGCT cis rs2458413 0.542 rs2514668 chr8:105362656 A/C cg04554929 chr8:105342491 NA -0.49 -5.88 -0.47 3.59e-8 Paget's disease; TGCT cis rs11779988 0.545 rs436506 chr8:17798243 A/G cg01800426 chr8:17659068 MTUS1 0.68 5.61 0.45 1.28e-7 Breast cancer; TGCT cis rs9677476 0.517 rs60664562 chr2:232060843 T/A cg07929768 chr2:232055508 NA 0.3 4.83 0.4 4.01e-6 Food antigen IgG levels; TGCT cis rs5769707 0.632 rs135876 chr22:50013573 A/G cg05373962 chr22:49881684 NA -0.29 -4.86 -0.4 3.53e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7954584 0.616 rs10743186 chr12:122356436 C/T cg10207240 chr12:122356781 WDR66 0.34 4.68 0.39 7.53e-6 Mean corpuscular volume; TGCT cis rs904251 0.504 rs12202664 chr6:37481198 A/G cg08126542 chr6:37504118 NA -0.44 -6.39 -0.5 2.99e-9 Cognitive performance; TGCT cis rs1461503 0.900 rs7107502 chr11:122830214 G/A cg27398637 chr11:122830231 C11orf63 -0.41 -4.77 -0.39 5.14e-6 Menarche (age at onset); TGCT cis rs4242434 0.927 rs34027561 chr8:22465385 T/C cg03733263 chr8:22462867 KIAA1967 1.14 20.27 0.88 3.6e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs8179 0.645 rs12531820 chr7:92257392 A/G cg15732164 chr7:92237376 CDK6 -0.27 -4.64 -0.38 8.79e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs2268241 0.938 rs9808753 chr21:34787312 A/G cg14850771 chr21:34775459 IFNGR2 0.61 4.9 0.4 2.93e-6 Obesity-related traits; TGCT cis rs7833790 0.777 rs6473301 chr8:82691340 A/G cg17211192 chr8:82754475 SNX16 -1.04 -8.46 -0.6 6.42e-14 Diastolic blood pressure; TGCT cis rs5750830 0.649 rs5750820 chr22:39825322 T/G cg24399712 chr22:39784796 NA -1.05 -12.52 -0.75 9.61e-24 Intelligence (multi-trait analysis); TGCT cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg25811766 chr13:21894605 NA 0.28 5.38 0.44 3.53e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg02493798 chr17:6899577 ALOX12 0.43 4.79 0.39 4.74e-6 Tonsillectomy; TGCT cis rs2229238 0.911 rs12405637 chr1:154501285 C/T cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs7568458 0.905 rs10187424 chr2:85794297 T/C cg02493740 chr2:85810744 VAMP5 -0.27 -4.86 -0.4 3.53e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1799949 1.000 rs1135214 chr17:41292323 T/C cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT cis rs644799 0.625 rs1255177 chr11:95471495 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.48 4.78 0.39 4.88e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7731657 0.537 rs973900 chr5:130362467 G/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg08439880 chr3:133502540 NA -0.34 -6.61 -0.51 1e-9 Iron status biomarkers; TGCT cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg03517284 chr6:25882590 NA -0.58 -6.03 -0.48 1.76e-8 Blood metabolite levels; TGCT cis rs2871473 0.951 rs1030025 chr2:103105611 A/T cg09003973 chr2:102972529 NA 0.64 4.52 0.38 1.4e-5 Blood protein levels; TGCT cis rs4788439 0.901 rs72770496 chr16:24972913 G/A cg07626409 chr16:25250191 ZKSCAN2 0.32 4.45 0.37 1.87e-5 Blood metabolite levels; TGCT cis rs35883536 0.647 rs17402665 chr1:101046940 C/T cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs10858047 0.883 rs11102827 chr1:115181843 C/T cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs7666738 0.830 rs13113899 chr4:99050422 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs7618501 0.602 rs2624853 chr3:50128893 A/G cg21659725 chr3:3221576 CRBN -0.73 -8.46 -0.6 6.37e-14 Intelligence (multi-trait analysis); TGCT cis rs453301 0.598 rs1025395 chr8:8836603 G/C cg06636001 chr8:8085503 FLJ10661 0.83 7.46 0.56 1.33e-11 Joint mobility (Beighton score); TGCT cis rs3749237 0.595 rs7643845 chr3:49530711 A/G cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT trans rs2469997 0.748 rs2470019 chr8:120362558 T/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs597539 0.615 rs583182 chr11:68678634 C/T cg21963583 chr11:68658836 MRPL21 0.37 6.15 0.48 9.57e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs8064299 0.967 rs878907 chr17:72769694 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.79 8.01 0.58 7.08e-13 Monocyte count; TGCT trans rs17471911 0.708 rs12218280 chr10:100787262 G/C cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs9325144 0.647 rs3759139 chr12:39087609 G/A cg10518543 chr12:38710700 ALG10B -0.49 -4.59 -0.38 1.05e-5 Morning vs. evening chronotype; TGCT cis rs7659604 0.521 rs4833232 chr4:122684367 C/T cg19748678 chr4:122722346 EXOSC9 -0.52 -5.27 -0.43 5.91e-7 Type 2 diabetes; TGCT cis rs7027203 0.964 rs7854075 chr9:96571211 G/A cg13679303 chr9:96623674 NA 0.67 9.97 0.67 1.47e-17 DNA methylation (variation); TGCT cis rs6964587 1.000 rs13224513 chr7:91601465 G/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6840360 0.554 rs13108359 chr4:152727852 T/C cg22705602 chr4:152727874 NA 0.35 6.1 0.48 1.23e-8 Intelligence (multi-trait analysis); TGCT cis rs9993613 0.875 rs1818655 chr4:73483204 C/T cg15102770 chr4:73434591 ADAMTS3 0.52 4.89 0.4 3.12e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs10207060 0.500 rs10177457 chr2:240708067 G/A cg15726768 chr2:241314588 NA -0.32 -4.49 -0.37 1.63e-5 Obesity-related traits; TGCT cis rs9443645 0.901 rs2050659 chr6:79734369 A/C cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs2228479 0.850 rs11646766 chr16:89838578 A/T cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs2204008 0.745 rs12146863 chr12:38502346 G/A cg13010199 chr12:38710504 ALG10B 0.6 4.88 0.4 3.15e-6 Bladder cancer; TGCT cis rs8070740 0.841 rs4790771 chr17:5324966 G/T cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs6076065 0.748 rs6076055 chr20:23333917 G/C cg11657817 chr20:23433608 CST11 0.31 5.29 0.43 5.46e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs7089973 0.604 rs7914792 chr10:116591391 T/C cg03647239 chr10:116582469 FAM160B1 0.59 5.75 0.46 6.46e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs8077577 0.945 rs11871039 chr17:18078904 C/G cg09161412 chr17:18057145 MYO15A -0.66 -5.36 -0.43 3.94e-7 Obesity-related traits; TGCT cis rs2594989 0.943 rs2595004 chr3:11406721 C/T cg00170343 chr3:11313890 ATG7 0.67 5.08 0.42 1.35e-6 Circulating chemerin levels; TGCT cis rs9467773 1.000 rs28558133 chr6:26531433 G/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs9419702 0.526 rs9419637 chr10:133548059 T/C cg20568497 chr10:133558893 NA 0.47 5.18 0.42 8.78e-7 Survival in rectal cancer; TGCT cis rs12540874 0.794 rs1470750 chr7:50576648 C/G cg18232548 chr7:50535776 DDC -0.36 -6.11 -0.48 1.17e-8 Systemic sclerosis; TGCT cis rs11690462 0.963 rs12471804 chr2:26559717 C/G cg04726446 chr2:26624865 C2orf39 0.42 4.58 0.38 1.14e-5 Coronary artery disease; TGCT cis rs4665809 0.590 rs62130493 chr2:26516418 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs10927875 0.722 rs1763606 chr1:16338282 A/G cg22431228 chr1:16359049 CLCNKA -0.26 -4.91 -0.4 2.79e-6 Dilated cardiomyopathy; TGCT cis rs7829975 0.686 rs907180 chr8:8702827 A/G cg15556689 chr8:8085844 FLJ10661 0.66 6.23 0.49 6.79e-9 Mood instability; TGCT cis rs2180341 1.000 rs3798850 chr6:127613966 C/T cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs67478160 0.608 rs11160760 chr14:104248938 G/T cg26031613 chr14:104095156 KLC1 -0.64 -6.57 -0.51 1.23e-9 Schizophrenia; TGCT cis rs981844 0.735 rs17371573 chr4:154765216 G/A cg14289246 chr4:154710475 SFRP2 1.01 8.9 0.62 5.78e-15 Response to statins (LDL cholesterol change); TGCT cis rs17221829 0.733 rs12277139 chr11:89389606 G/A cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs904251 0.861 rs914349 chr6:37484715 A/C cg01843034 chr6:37503916 NA -0.5 -6.23 -0.49 6.73e-9 Cognitive performance; TGCT trans rs7824557 0.547 rs2409749 chr8:11078949 G/A cg15556689 chr8:8085844 FLJ10661 -0.85 -8.06 -0.59 5.56e-13 Retinal vascular caliber; TGCT trans rs2727020 0.731 rs10450572 chr11:49281073 T/C cg03929089 chr4:120376271 NA 0.73 8.48 0.61 5.75e-14 Coronary artery disease; TGCT cis rs7584330 0.554 rs6740722 chr2:238393288 T/C cg14458575 chr2:238380390 NA 0.58 5.05 0.41 1.53e-6 Prostate cancer; TGCT trans rs877282 0.628 rs11253435 chr10:824169 T/C cg22713356 chr15:30763199 NA 0.89 6.71 0.52 6.19e-10 Uric acid levels; TGCT cis rs1008375 0.863 rs2058336 chr4:17608299 T/C cg10189774 chr4:17578691 LAP3 0.57 4.9 0.4 2.93e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.679 rs72649114 chr8:58037491 G/T cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs2191566 0.664 rs62115477 chr19:44543027 T/G cg03039196 chr19:44506973 ZNF230 0.53 4.47 0.37 1.78e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs9467773 1.000 rs1884946 chr6:26545308 C/G cg15659132 chr6:26577336 NA 0.86 12.17 0.74 6.67e-23 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.593 rs6542920 chr2:100845088 A/G cg22139774 chr2:100720529 AFF3 -0.3 -4.52 -0.38 1.41e-5 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9534288 0.699 rs2897028 chr13:46656915 C/T cg15192986 chr13:46630673 CPB2 -0.53 -6.39 -0.5 3.01e-9 Blood protein levels; TGCT cis rs78487399 0.808 rs12104615 chr2:43676938 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs35306767 0.633 rs17221491 chr10:1065191 A/G cg20503657 chr10:835505 NA 0.59 6.61 0.51 1.03e-9 Eosinophil percentage of granulocytes; TGCT cis rs2180341 1.000 rs6569482 chr6:127631371 C/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs1729951 0.575 rs1654923 chr3:136692620 A/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs7973719 0.833 rs7970916 chr12:7357746 T/C cg07052231 chr12:7363540 PEX5 0.37 5.74 0.46 6.97e-8 IgG glycosylation; TGCT cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg17554472 chr22:41940697 POLR3H 0.47 5.04 0.41 1.63e-6 Vitiligo; TGCT cis rs2227564 0.620 rs11000765 chr10:75512452 G/C cg04320760 chr10:75533139 FUT11 -0.32 -4.55 -0.38 1.28e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs7833790 0.685 rs13255262 chr8:82728024 T/G cg23324259 chr8:82754387 SNX16 -0.61 -4.71 -0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.07 -13.45 -0.77 5.59e-26 Prudent dietary pattern; TGCT cis rs17001868 0.568 rs2294350 chr22:40784278 C/T cg07138101 chr22:40742427 ADSL 0.73 5.47 0.44 2.38e-7 Mammographic density (dense area); TGCT cis rs858239 0.539 rs6945510 chr7:23192240 C/T cg05602783 chr7:23145260 KLHL7 -0.62 -4.95 -0.41 2.37e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9534288 0.797 rs992631 chr13:46591989 A/G cg15192986 chr13:46630673 CPB2 0.5 7.16 0.54 6.27e-11 Blood protein levels; TGCT cis rs7666738 0.719 rs35184673 chr4:99050945 T/C cg05340658 chr4:99064831 C4orf37 0.53 4.57 0.38 1.16e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs77633900 0.614 rs280001 chr15:77003566 C/A cg21673338 chr15:77095150 SCAPER -0.53 -5.22 -0.42 7.33e-7 Non-glioblastoma glioma;Glioma; TGCT cis rs735396 0.595 rs2258287 chr12:121454313 G/T cg02403541 chr12:121454288 C12orf43 0.86 9.56 0.65 1.5e-16 N-glycan levels; TGCT cis rs8050907 0.744 rs8055559 chr16:4540227 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.58 4.73 0.39 6.09e-6 Obesity-related traits; TGCT cis rs4919694 1.000 rs17727391 chr10:104836101 C/A cg04362960 chr10:104952993 NT5C2 1.07 7.2 0.54 5.11e-11 Arsenic metabolism; TGCT cis rs8062405 1.000 rs62037367 chr16:28874547 C/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs11690935 0.959 rs12692974 chr2:172663256 T/C cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs7833790 0.724 rs6473299 chr8:82676936 A/G cg27398817 chr8:82754497 SNX16 -0.82 -5.97 -0.47 2.29e-8 Diastolic blood pressure; TGCT cis rs727505 1.000 rs28844358 chr7:124562695 A/C cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs10504229 0.683 rs77548248 chr8:58117542 G/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs3096299 0.509 rs4785691 chr16:89597221 A/G cg06640241 chr16:89574553 SPG7 0.88 11.32 0.71 7.77e-21 Multiple myeloma (IgH translocation); TGCT cis rs7216064 1.000 rs4791212 chr17:65975385 C/T cg12091567 chr17:66097778 LOC651250 -0.8 -6.14 -0.48 1.02e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9611565 0.918 rs9611561 chr22:41757234 C/G cg13695892 chr22:41940480 POLR3H -0.92 -9.08 -0.63 2.06e-15 Vitiligo; TGCT cis rs11190604 1.000 rs57025426 chr10:102205868 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9993613 0.778 rs962191 chr4:73419495 T/C cg15102770 chr4:73434591 ADAMTS3 0.58 5.29 0.43 5.27e-7 Hip circumference adjusted for BMI;Height; TGCT cis rs2070488 0.775 rs7374458 chr3:38531211 T/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.76 7.41 0.55 1.72e-11 Electrocardiographic conduction measures; TGCT cis rs3540 0.576 rs1974519 chr15:91036460 A/G cg22089800 chr15:90895588 ZNF774 0.76 7.77 0.57 2.62e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs72781680 0.848 rs55725028 chr2:23966447 A/G cg08917208 chr2:24149416 ATAD2B 0.95 6.09 0.48 1.28e-8 Lymphocyte counts; TGCT cis rs72615157 0.595 rs112241539 chr7:99847237 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.69 5.32 0.43 4.67e-7 Lung function (FEV1/FVC); TGCT cis rs2832077 0.506 rs2832088 chr21:30158620 G/A cg24692254 chr21:30365293 RNF160 -0.61 -5.35 -0.43 4.03e-7 Cognitive test performance; TGCT cis rs2075371 0.829 rs10954442 chr7:134007587 A/G cg11752832 chr7:134001865 SLC35B4 -0.75 -6.83 -0.52 3.45e-10 Mean platelet volume; TGCT cis rs3733585 0.699 rs4408959 chr4:9948868 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.48 -0.5 1.95e-9 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs1814175 0.645 rs847630 chr11:49926360 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT trans rs208520 0.690 rs1304672 chr6:66847973 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.94 9.45 0.65 2.74e-16 Exhaled nitric oxide output; TGCT cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg09904177 chr6:26538194 HMGN4 0.68 6.27 0.49 5.41e-9 Intelligence (multi-trait analysis); TGCT cis rs10089 0.904 rs2228112 chr5:127469859 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.53 0.56 9.3e-12 Ileal carcinoids; TGCT cis rs887807 0.764 rs200556 chr9:123071678 C/G cg14457452 chr9:123257038 CDK5RAP2 0.71 5.24 0.43 6.57e-7 Photic sneeze reflex; TGCT cis rs4455778 0.659 rs34031293 chr7:49027864 G/C cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT trans rs1814175 0.647 rs10839394 chr11:49844747 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.39e-11 Height; TGCT cis rs7660520 0.524 rs114404677 chr4:183733832 G/A cg04181038 chr4:183730758 NA 0.65 6.02 0.48 1.86e-8 Pediatric autoimmune diseases; TGCT cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg07061783 chr6:25882402 NA -0.56 -5.36 -0.43 3.95e-7 Intelligence (multi-trait analysis); TGCT cis rs314370 0.951 rs17881696 chr7:100493359 G/A cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs2342371 0.848 rs13092653 chr3:196200188 C/T cg15048948 chr3:196158458 UBXN7 -0.54 -4.66 -0.39 7.97e-6 Fat distribution (HIV); TGCT cis rs7572733 0.534 rs1464209 chr2:198814396 A/G cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs2075371 1.000 rs2544213 chr7:133982867 G/C cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs7267979 0.586 rs6050431 chr20:25183908 C/T cg14121845 chr20:25566513 NINL 0.45 4.88 0.4 3.23e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.754 rs6570708 chr6:145989428 C/T cg13319975 chr6:146136371 FBXO30 0.57 5.2 0.42 8.12e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10791097 0.694 rs1054869 chr11:130742630 G/A cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6978712 0.929 rs56036294 chr7:127152275 C/T cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs10851411 0.862 rs8033412 chr15:42822289 C/T cg23803468 chr15:43513504 EPB42 0.29 5.38 0.43 3.6e-7 Glucose homeostasis traits; TGCT cis rs4665809 0.793 rs6546715 chr2:26261520 G/A cg25036284 chr2:26402008 FAM59B -0.55 -4.76 -0.39 5.33e-6 Gut microbiome composition (summer); TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.61 -0.38 9.96e-6 Prudent dietary pattern; TGCT cis rs79057730 0.599 rs4333501 chr7:803244 C/T cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.41 0.44 3.16e-7 Initial pursuit acceleration; TGCT cis rs477895 1.000 rs7938380 chr11:64034866 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.32 0.43 4.6e-7 Mean platelet volume; TGCT cis rs9902453 0.765 rs2628167 chr17:28064498 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.39 -0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs1008375 0.966 rs6449313 chr4:17588320 A/G cg18681998 chr4:17616180 MED28 0.87 8.54 0.61 4.02e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7647973 1.000 rs7648995 chr3:49438803 C/T cg07636037 chr3:49044803 WDR6 -0.72 -5.79 -0.46 5.35e-8 Menarche (age at onset); TGCT cis rs10779751 0.762 rs3010222 chr1:11326922 T/C cg08854313 chr1:11322531 MTOR -0.84 -9.22 -0.64 9.84e-16 Body mass index; TGCT cis rs7120118 0.517 rs3758674 chr11:47278938 T/C cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.16e-7 HDL cholesterol; TGCT cis rs56104184 0.775 rs56317021 chr19:49395960 C/T cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs651907 0.557 rs34181125 chr3:101490278 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 11.22 0.71 1.34e-20 Colorectal cancer; TGCT cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT trans rs916888 0.610 rs199454 chr17:44800110 G/A cg01341218 chr17:43662625 NA -0.83 -7.46 -0.56 1.34e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9818758 0.607 rs11719220 chr3:49245201 A/G cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2404602 0.716 rs56216512 chr15:76686936 T/C cg22467129 chr15:76604101 ETFA -0.59 -7.11 -0.54 7.92e-11 Blood metabolite levels; TGCT cis rs853679 0.517 rs9366715 chr6:28064633 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs8016982 0.674 rs11159494 chr14:81667611 G/C cg01989461 chr14:81687754 GTF2A1 0.81 8.45 0.6 6.73e-14 Schizophrenia; TGCT cis rs4523957 0.590 rs9899427 chr17:2063550 A/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12477438 0.765 rs10193039 chr2:99692373 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.82 -8.08 -0.59 4.94e-13 Chronic sinus infection; TGCT cis rs10206020 0.885 rs11886082 chr2:1576683 T/C cg12573674 chr2:1569213 NA -0.46 -5.28 -0.43 5.66e-7 IgG glycosylation; TGCT cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg17971929 chr21:40555470 PSMG1 -0.67 -6.0 -0.47 1.99e-8 Cognitive function; TGCT cis rs8078723 0.714 rs8070444 chr17:38151960 A/G cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs12510870 0.599 rs1919469 chr4:74404245 G/A cg05868023 chr4:75230803 EREG 0.56 5.14 0.42 1.06e-6 Iris color (b* coordinate); TGCT cis rs921968 0.541 rs17572485 chr2:219296545 C/T cg02176678 chr2:219576539 TTLL4 -0.46 -6.75 -0.52 5.03e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2153535 0.580 rs9379222 chr6:8514788 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs3784262 0.669 rs4646645 chr15:58245151 A/G cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.3 -0.49 4.81e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs10984561 0.748 rs116158226 chr9:122248570 G/A cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs72781680 0.821 rs116583405 chr2:24208221 T/C cg08917208 chr2:24149416 ATAD2B 0.72 4.5 0.37 1.56e-5 Lymphocyte counts; TGCT cis rs12815613 0.539 rs7300883 chr12:121459440 C/G cg02403541 chr12:121454288 C12orf43 -0.58 -5.36 -0.43 3.94e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6582630 0.539 rs4882324 chr12:38499180 T/C cg26384229 chr12:38710491 ALG10B -0.55 -4.91 -0.4 2.86e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2204008 0.774 rs7959048 chr12:37948276 T/A cg13010199 chr12:38710504 ALG10B 0.63 5.0 0.41 1.93e-6 Bladder cancer; TGCT cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs3020736 0.500 rs7292241 chr22:42492063 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.85e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11690935 0.959 rs3770451 chr2:172668715 T/G cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs10789491 1.000 rs618505 chr1:47144532 T/C cg15501359 chr1:47185051 KIAA0494 0.81 8.17 0.59 2.99e-13 Response to hepatitis C treatment; TGCT cis rs10871290 0.650 rs3760055 chr16:74490529 G/A cg01733217 chr16:74700730 RFWD3 0.58 4.46 0.37 1.8e-5 Breast cancer; TGCT cis rs910187 0.572 rs6018325 chr20:45810335 A/G cg27589058 chr20:45804311 EYA2 -0.38 -8.34 -0.6 1.18e-13 Migraine; TGCT cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg23262073 chr20:60523788 NA 0.34 5.56 0.45 1.57e-7 Obesity-related traits; TGCT cis rs263156 0.903 rs2077836 chr6:142922061 T/C cg18419694 chr6:143832440 FUCA2 0.43 4.94 0.41 2.48e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs858239 0.600 rs10235786 chr7:23139940 T/C cg05602783 chr7:23145260 KLHL7 -0.66 -5.45 -0.44 2.57e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs896854 0.654 rs896847 chr8:95972551 G/A cg16049864 chr8:95962084 TP53INP1 -0.75 -10.47 -0.69 9.05e-19 Type 2 diabetes; TGCT cis rs595982 0.546 rs9941490 chr19:49396737 G/A cg21252483 chr19:49399788 TULP2 -0.3 -5.05 -0.41 1.54e-6 Red cell distribution width; TGCT cis rs933688 1.000 rs6452953 chr5:90723034 T/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 9.92 0.67 2e-17 Smoking behavior; TGCT cis rs986417 0.818 rs7153263 chr14:61099261 G/A cg27398547 chr14:60952738 C14orf39 1.44 10.1 0.67 7.17e-18 Gut microbiota (bacterial taxa); TGCT cis rs1843834 0.898 rs2015099 chr2:225519915 T/C cg22455342 chr2:225449267 CUL3 0.74 7.25 0.55 3.9e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs739401 0.572 rs7111857 chr11:3068106 A/G cg05729581 chr11:3078854 CARS 0.58 5.5 0.44 2.11e-7 Longevity; TGCT cis rs2932538 0.922 rs6671645 chr1:113129128 A/G cg22162597 chr1:113214053 CAPZA1 0.25 5.6 0.45 1.34e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs17376456 0.877 rs13173952 chr5:93307557 A/T cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs881375 0.967 rs7046108 chr9:123660339 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.47 -5.18 -0.42 8.9e-7 Rheumatoid arthritis; TGCT cis rs861020 0.563 rs61820640 chr1:210041297 G/T cg05527609 chr1:210001259 C1orf107 -0.99 -7.56 -0.56 7.95e-12 Orofacial clefts; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg04234412 chr22:24373322 LOC391322 -0.9 -10.36 -0.68 1.73e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9906944 0.933 rs35051752 chr17:47089908 G/A cg20966754 chr17:47091339 IGF2BP1 -0.43 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs4566357 0.615 rs12474622 chr2:227912793 A/G cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.9e-7 Coronary artery disease; TGCT cis rs3820928 0.874 rs7605032 chr2:227847630 T/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.59 -0.38 1.05e-5 Pulmonary function; TGCT cis rs7104764 0.879 rs6421986 chr11:221659 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.05 10.74 0.69 2e-19 Menarche (age at onset); TGCT trans rs8073060 0.586 rs225296 chr17:33924847 C/G cg19694781 chr19:47549865 TMEM160 -0.61 -13.7 -0.78 1.39e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs12620999 0.941 rs62183344 chr2:237979165 T/C cg23555395 chr2:238036564 NA 0.27 4.76 0.39 5.28e-6 Systemic lupus erythematosus; TGCT cis rs523522 0.962 rs12371550 chr12:120987643 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs3820068 0.581 rs16851848 chr1:15927698 G/A cg05660106 chr1:15850417 CASP9 0.84 8.28 0.6 1.63e-13 Systolic blood pressure; TGCT cis rs36051895 0.632 rs12115301 chr9:5180548 A/G cg02405213 chr9:5042618 JAK2 0.75 10.09 0.67 7.75e-18 Pediatric autoimmune diseases; TGCT cis rs7829975 0.514 rs2945873 chr8:8260445 C/T cg08975724 chr8:8085496 FLJ10661 0.58 5.03 0.41 1.65e-6 Mood instability; TGCT cis rs524281 0.814 rs10896093 chr11:65958411 C/G cg00563793 chr11:65837595 PACS1 0.52 4.5 0.37 1.55e-5 Electroencephalogram traits; TGCT cis rs644799 0.648 rs1255181 chr11:95472148 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.5 4.8 0.4 4.53e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs372883 0.648 rs1153288 chr21:30686091 A/G cg24692254 chr21:30365293 RNF160 0.53 5.16 0.42 9.57e-7 Pancreatic cancer; TGCT cis rs8072100 0.790 rs6505048 chr17:45674998 G/A cg10024583 chr17:45772800 TBKBP1 -0.43 -4.47 -0.37 1.76e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4722166 0.630 rs4722168 chr7:22779002 G/A cg26061582 chr7:22766209 IL6 0.58 7.41 0.55 1.66e-11 Lung cancer; TGCT trans rs901683 0.702 rs78034568 chr10:46149580 G/C cg03466342 chr12:52753899 KRT85 -0.58 -7.16 -0.54 6.39e-11 Red blood cell traits;Mean corpuscular volume; TGCT cis rs6060960 0.537 rs75351461 chr20:30458612 C/T cg06102403 chr20:30458708 TTLL9;DUSP15 0.43 5.12 0.42 1.16e-6 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs2742417 1.000 rs2742447 chr3:45763977 C/T cg04837898 chr3:45731254 SACM1L -0.51 -5.38 -0.43 3.6e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2997447 0.706 rs55657303 chr1:26421012 A/G cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg08439880 chr3:133502540 NA -0.28 -5.15 -0.42 9.73e-7 Iron status biomarkers; TGCT cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.519 rs72966020 chr2:219642620 C/G cg02176678 chr2:219576539 TTLL4 -0.48 -6.3 -0.49 4.75e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs769267 0.896 rs2315610 chr19:19597240 T/C cg08509172 chr19:19383838 TM6SF2 -0.35 -4.6 -0.38 1.02e-5 Tonsillectomy; TGCT cis rs11696501 0.739 rs6073784 chr20:44201931 T/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.79 -0.4 4.67e-6 Brain structure; TGCT cis rs7829975 0.511 rs2921028 chr8:8340477 T/C cg08975724 chr8:8085496 FLJ10661 0.56 5.41 0.44 3.1e-7 Mood instability; TGCT cis rs986417 0.606 rs7156375 chr14:61110627 G/A cg27398547 chr14:60952738 C14orf39 1.45 9.82 0.66 3.5e-17 Gut microbiota (bacterial taxa); TGCT cis rs7267979 0.816 rs443009 chr20:25499817 A/G cg16686733 chr20:25566563 NINL -0.47 -4.65 -0.39 8.28e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs739496 0.615 rs627308 chr12:112146555 A/C cg10833066 chr12:111807467 FAM109A -0.36 -5.06 -0.41 1.46e-6 Platelet count; TGCT cis rs1075232 0.826 rs16956738 chr15:31736231 C/T cg01030201 chr15:31746330 NA 1.0 5.29 0.43 5.44e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs4949448 1.000 rs4949448 chr1:32062066 A/C cg13919466 chr1:32135498 COL16A1 0.37 5.12 0.42 1.15e-6 Intelligence (multi-trait analysis); TGCT cis rs4713118 0.662 rs9468276 chr6:28027688 A/C cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs12220898 0.749 rs4838479 chr10:50476682 C/T cg06072769 chr10:50146962 WDFY4 0.35 4.5 0.37 1.56e-5 Inflammatory biomarkers; TGCT cis rs13064411 0.542 rs11537650 chr3:113222036 G/A cg18753928 chr3:113234510 CCDC52 -0.56 -4.72 -0.39 6.3e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2243480 1.000 rs4149468 chr7:65825690 T/C cg07424592 chr7:64974309 NA 1.27 7.28 0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs367615 0.918 rs10051855 chr5:108859958 G/A cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT trans rs10435719 0.834 rs11250176 chr8:11792816 A/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs6901250 0.632 rs688961 chr6:117089080 A/T cg12892004 chr6:117198278 RFX6 0.39 4.64 0.38 8.6e-6 C-reactive protein levels; TGCT cis rs611744 0.870 rs596703 chr8:109160146 A/G cg21045802 chr8:109455806 TTC35 -0.69 -6.06 -0.48 1.51e-8 Dupuytren's disease; TGCT cis rs7267979 0.873 rs6037062 chr20:25202892 G/A cg03522245 chr20:25566470 NINL 0.55 5.95 0.47 2.6e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1878931 0.535 rs10852706 chr16:3412582 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.73 6.0 0.47 2.01e-8 Body mass index (adult); TGCT cis rs854765 0.547 rs8069811 chr17:17922280 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.41 0.6 8.09e-14 Total body bone mineral density; TGCT cis rs7246657 0.943 rs10420754 chr19:37959372 C/G cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs12477438 0.501 rs12613624 chr2:99732741 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.75 -7.25 -0.55 3.92e-11 Chronic sinus infection; TGCT cis rs7772486 0.875 rs6934467 chr6:146410529 G/T cg05347473 chr6:146136440 FBXO30 0.54 5.11 0.42 1.18e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs793571 0.669 rs28864995 chr15:58945671 T/G cg05156742 chr15:59063176 FAM63B 0.51 4.77 0.39 5.04e-6 Schizophrenia; TGCT cis rs7975161 0.630 rs4129598 chr12:104620638 T/C cg25273343 chr12:104657179 TXNRD1 -0.42 -5.71 -0.46 7.85e-8 Toenail selenium levels; TGCT cis rs17473412 0.784 rs114334621 chr5:122702574 G/T cg15125798 chr5:122621645 NA -0.57 -4.83 -0.4 3.88e-6 Total body bone mineral density; TGCT cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg05896524 chr21:47604654 C21orf56 -0.43 -4.54 -0.38 1.31e-5 Testicular germ cell tumor; TGCT cis rs28595532 1.000 rs114778020 chr4:119662584 C/A cg14228332 chr4:119757509 SEC24D 1.06 5.75 0.46 6.55e-8 Cannabis dependence symptom count; TGCT cis rs4862750 0.914 rs6837117 chr4:187872379 C/T cg11301795 chr4:187892539 NA -0.34 -5.03 -0.41 1.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1034435 0.692 rs6008739 chr22:48892542 T/C cg05992904 chr22:48892994 FAM19A5 -0.34 -4.65 -0.39 8.44e-6 Late-onset Alzheimer's disease; TGCT cis rs597539 0.652 rs544370 chr11:68653232 C/T cg04772025 chr11:68637568 NA 0.59 6.61 0.51 1.04e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11648796 0.759 rs12597195 chr16:769026 G/C cg27144592 chr16:783916 NARFL 0.43 5.83 0.46 4.42e-8 Height; TGCT cis rs35306767 0.903 rs12264711 chr10:929525 T/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs3796352 1.000 rs34943350 chr3:53012888 C/T cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10927875 0.894 rs10927878 chr1:16319957 C/T cg22431228 chr1:16359049 CLCNKA 0.23 4.44 0.37 1.94e-5 Dilated cardiomyopathy; TGCT cis rs7617773 0.780 rs13084616 chr3:48339699 A/G cg11946769 chr3:48343235 NME6 -0.83 -7.23 -0.54 4.25e-11 Coronary artery disease; TGCT cis rs644799 0.965 rs11021305 chr11:95498269 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.45 0.6 6.69e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10782582 0.632 rs77099976 chr1:76240524 T/C cg10523679 chr1:76189770 ACADM -0.53 -4.98 -0.41 2.04e-6 Daytime sleep phenotypes; TGCT trans rs2688608 0.618 rs28718766 chr10:75489844 C/A cg13918328 chr10:52500089 ASAH2B 0.68 6.73 0.52 5.68e-10 Inflammatory bowel disease; TGCT cis rs35883536 0.626 rs11799819 chr1:101049382 G/A cg10298815 chr1:101004474 GPR88 -0.25 -4.57 -0.38 1.17e-5 Monocyte count; TGCT cis rs6964587 0.773 rs2097810 chr7:91977226 G/A cg17063962 chr7:91808500 NA 0.83 8.18 0.59 2.83e-13 Breast cancer; TGCT cis rs4689388 0.926 rs11725494 chr4:6293855 C/T cg00701064 chr4:6280414 WFS1 0.44 5.74 0.46 6.95e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs853679 0.546 rs200952 chr6:27836976 C/T cg08798685 chr6:27730294 NA -0.34 -4.69 -0.39 7.2e-6 Depression; TGCT trans rs77457752 0.690 rs12335400 chr9:13912195 A/G cg12973904 chr7:149457885 NA 0.46 7.07 0.54 9.92e-11 Breast cancer; TGCT cis rs9300255 0.568 rs3018098 chr12:123654812 T/C cg00376283 chr12:123451042 ABCB9 0.72 5.55 0.45 1.65e-7 Neutrophil percentage of white cells; TGCT cis rs4862307 1.000 rs4493587 chr4:185000525 C/T cg06737308 chr4:185021514 ENPP6 0.44 6.7 0.52 6.5e-10 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs12142240 0.698 rs56344958 chr1:46814518 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6545883 0.895 rs2256617 chr2:61679924 A/G cg15711740 chr2:61764176 XPO1 -0.52 -4.74 -0.39 5.8e-6 Tuberculosis; TGCT cis rs394563 0.559 rs7753269 chr6:149671360 G/A cg16235748 chr6:149772707 ZC3H12D 0.44 5.06 0.41 1.47e-6 Dupuytren's disease; TGCT cis rs10875746 0.556 rs4760619 chr12:48499931 A/T cg20731937 chr12:48336164 NA 0.68 4.8 0.4 4.4e-6 Longevity (90 years and older); TGCT cis rs12142240 0.698 rs56049453 chr1:46835468 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg22963979 chr7:1858916 MAD1L1 -0.41 -6.39 -0.5 3.02e-9 Bipolar disorder and schizophrenia; TGCT cis rs1420338 0.933 rs10228731 chr7:34150782 G/T cg01275685 chr7:34179230 BMPER -0.27 -4.84 -0.4 3.82e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs67340775 0.541 rs169287 chr6:27854760 C/A cg26587870 chr6:27730563 NA -0.34 -4.62 -0.38 9.28e-6 Lung cancer in ever smokers; TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.5 5.16 0.42 9.61e-7 Lymphocyte counts; TGCT cis rs4409675 0.527 rs1884469 chr1:28239434 G/A cg23691781 chr1:28212827 C1orf38 0.28 5.82 0.46 4.74e-8 Corneal astigmatism; TGCT cis rs514406 0.861 rs1412706 chr1:53237721 G/A cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs1008375 0.932 rs964012 chr4:17619184 A/G cg10189774 chr4:17578691 LAP3 0.64 5.47 0.44 2.42e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7017914 0.935 rs6472551 chr8:71781849 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.51 -4.68 -0.39 7.35e-6 Bone mineral density; TGCT cis rs9467773 1.000 rs3736781 chr6:26505362 G/A cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.882 rs56224841 chr3:10044014 A/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs2857078 0.627 rs1476512 chr17:42330122 C/T cg13607699 chr17:42295918 UBTF -0.6 -5.55 -0.45 1.68e-7 Red cell distribution width;Reticulocyte count; TGCT cis rs12220898 0.833 rs3996895 chr10:50484365 G/A cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT trans rs6089829 0.962 rs6062777 chr20:61663748 G/A cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs595982 0.546 rs10401443 chr19:49402059 C/A cg15549821 chr19:49342101 PLEKHA4 -0.39 -5.29 -0.43 5.24e-7 Red cell distribution width; TGCT cis rs227917 1.000 rs6959005 chr7:23696342 G/C cg12601843 chr7:23510954 IGF2BP3 0.56 4.49 0.37 1.6e-5 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs9393692 0.905 rs1125000 chr6:26287256 C/T cg00631329 chr6:26305371 NA -0.41 -6.14 -0.48 1.01e-8 Educational attainment; TGCT cis rs17376456 1.000 rs34756085 chr5:93556294 A/G cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.72e-12 Diabetic retinopathy; TGCT cis rs2688608 0.836 rs2675668 chr10:75636148 G/A cg04320760 chr10:75533139 FUT11 -0.31 -4.8 -0.4 4.49e-6 Inflammatory bowel disease; TGCT cis rs751728 0.664 rs2395402 chr6:33753673 G/A cg13859433 chr6:33739653 LEMD2 -0.32 -5.71 -0.46 7.84e-8 Crohn's disease; TGCT cis rs11239930 1.000 rs11239930 chr1:146560564 C/T cg00044796 chr1:146552390 NA -0.32 -4.51 -0.38 1.5e-5 AIDS progression; TGCT cis rs951366 0.789 rs823094 chr1:205689807 G/T cg11965913 chr1:205819406 PM20D1 -0.45 -4.44 -0.37 1.96e-5 Menarche (age at onset); TGCT trans rs7824557 0.564 rs2572386 chr8:11236975 A/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs7617480 0.648 rs7653408 chr3:48972351 A/C cg07636037 chr3:49044803 WDR6 0.8 6.66 0.51 8.03e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs10256972 0.642 rs6961424 chr7:1004113 T/C cg07930192 chr7:1003750 NA 0.3 4.66 0.39 8.07e-6 Longevity;Endometriosis; TGCT cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7312933 0.703 rs1059360 chr12:42554505 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2046867 0.862 rs67961837 chr3:72840877 T/G cg25664220 chr3:72788482 NA -0.56 -7.01 -0.53 1.34e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9611565 0.659 rs9611603 chr22:41912750 A/G cg13695892 chr22:41940480 POLR3H -0.9 -9.03 -0.63 2.7e-15 Vitiligo; TGCT cis rs6951245 1.000 rs11768761 chr7:1069807 A/G cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg25036284 chr2:26402008 FAM59B -0.61 -4.93 -0.4 2.59e-6 Gut microbiome composition (summer); TGCT cis rs2836974 0.583 rs2776306 chr21:40713754 A/G cg11644478 chr21:40555479 PSMG1 0.64 6.22 0.49 7.07e-9 Cognitive function; TGCT cis rs7659604 0.539 rs3217773 chr4:122739121 A/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.26 -0.43 6.07e-7 Type 2 diabetes; TGCT cis rs12368653 0.525 rs1564374 chr12:58010163 C/T cg00700412 chr12:58011837 NA 0.23 4.57 0.38 1.16e-5 Multiple sclerosis; TGCT cis rs67478160 0.643 rs876002 chr14:104239697 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.57 -0.51 1.25e-9 Schizophrenia; TGCT cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs9457247 0.534 rs2345568 chr6:167381804 A/G cg23791538 chr6:167370224 RNASET2 0.65 6.48 0.5 1.96e-9 Crohn's disease; TGCT cis rs6840360 0.642 rs6851814 chr4:152346437 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.41 -0.5 2.81e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs28728124 chr4:99001116 G/T cg05340658 chr4:99064831 C4orf37 0.46 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs56104184 0.723 rs73063522 chr19:49408358 C/G cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2769264 1.000 rs6684085 chr1:151357333 C/T cg18801370 chr1:151430492 POGZ -0.56 -5.84 -0.46 4.33e-8 Blood trace element (Cu levels); TGCT cis rs9560113 1.000 rs9555807 chr13:112179965 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg10862848 chr6:42927986 GNMT -0.38 -4.67 -0.39 7.65e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs270601 0.721 rs270621 chr5:131605821 C/A cg24060327 chr5:131705240 SLC22A5 -0.65 -6.57 -0.51 1.26e-9 Acylcarnitine levels; TGCT cis rs9467711 0.659 rs35304979 chr6:26356347 C/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs595982 0.510 rs3826817 chr19:49401444 C/T cg15549821 chr19:49342101 PLEKHA4 -0.39 -5.29 -0.43 5.24e-7 Red cell distribution width; TGCT cis rs453301 0.658 rs12114954 chr8:8904862 T/G cg15556689 chr8:8085844 FLJ10661 -0.67 -5.46 -0.44 2.51e-7 Joint mobility (Beighton score); TGCT cis rs1723838 0.826 rs17244671 chr11:73574422 A/C cg18195628 chr11:73498948 MRPL48 0.94 4.49 0.37 1.6e-5 Obesity-related traits; TGCT cis rs7611238 0.560 rs7616598 chr3:195110186 G/A cg27323046 chr3:195102265 ACAP2 0.37 4.93 0.4 2.56e-6 Body mass index; TGCT cis rs854572 0.600 rs705382 chr7:94955221 C/G cg04155289 chr7:94953770 PON1 -0.37 -6.34 -0.49 3.86e-9 Paraoxonase activity; TGCT cis rs42648 0.869 rs1015404 chr7:89913946 G/C cg25739043 chr7:89950458 NA -0.73 -7.31 -0.55 2.87e-11 Homocysteine levels; TGCT cis rs2974760 0.606 rs2858918 chr16:201183 T/C cg08400316 chr16:204221 HBZ 0.67 6.33 0.49 4.03e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7044106 0.762 rs1324473 chr9:123404610 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 -0.62 -6.69 -0.52 6.69e-10 Hip circumference adjusted for BMI; TGCT cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg22920501 chr2:26401640 FAM59B 0.83 5.42 0.44 3.04e-7 Gut microbiome composition (summer); TGCT cis rs782590 0.967 rs782586 chr2:55836165 A/C cg18811423 chr2:55921094 PNPT1 0.65 6.88 0.53 2.6e-10 Metabolic syndrome; TGCT cis rs79349575 0.783 rs12601955 chr17:47034420 C/T cg26022315 chr17:47021804 SNF8 0.47 4.61 0.38 9.94e-6 Type 2 diabetes; TGCT cis rs1577917 1.000 rs6940458 chr6:86644992 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs4819052 0.851 rs7279182 chr21:46656112 G/A cg06618935 chr21:46677482 NA -0.36 -5.48 -0.44 2.23e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.57 -5.67 -0.45 9.59e-8 Electroencephalogram traits; TGCT cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs2997447 0.761 rs61776575 chr1:26429844 G/A cg03844060 chr1:26490628 NA 0.28 4.6 0.38 1.02e-5 QRS complex (12-leadsum); TGCT cis rs7010267 0.596 rs7013203 chr8:120017159 C/T cg17171407 chr8:119960777 TNFRSF11B -0.26 -4.59 -0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs1997103 1.000 rs6593233 chr7:55406200 C/T cg17469321 chr7:55412551 NA -0.63 -6.39 -0.5 3.09e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg04944784 chr2:26401820 FAM59B -0.78 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT trans rs10506458 1.000 rs10506458 chr12:63445092 G/A cg22491629 chr6:157744540 C6orf35 -0.96 -8.34 -0.6 1.21e-13 Hemostatic factors and hematological phenotypes; TGCT cis rs17826219 0.706 rs57698184 chr17:29064918 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Body mass index; TGCT cis rs9926296 0.682 rs645019 chr16:89716883 C/T cg01097406 chr16:89675127 NA 0.36 6.24 0.49 6.21e-9 Vitiligo; TGCT cis rs7659604 0.592 rs56077950 chr4:122721412 C/T cg19748678 chr4:122722346 EXOSC9 0.94 9.89 0.66 2.3e-17 Type 2 diabetes; TGCT cis rs73198271 0.855 rs57301822 chr8:8608642 C/T cg06671706 chr8:8559999 CLDN23 -0.37 -4.67 -0.39 7.55e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2832191 0.550 rs66484040 chr21:30511691 G/A cg24692254 chr21:30365293 RNF160 -0.61 -5.41 -0.44 3.08e-7 Dental caries; TGCT cis rs10992471 0.533 rs331377 chr9:95243549 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.76 -0.46 6.34e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10504229 0.683 rs11785260 chr8:58132906 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs1525293 0.659 rs4719054 chr7:70517130 C/T cg21135135 chr7:70597687 WBSCR17 0.49 4.61 0.38 9.91e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs13191362 0.810 rs13200053 chr6:163011443 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9900497 0.504 rs2228100 chr17:19642952 C/G cg22552966 chr17:19620595 SLC47A2 0.2 5.21 0.42 7.56e-7 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs10131894 0.575 rs1860935 chr14:75432464 G/A cg06637938 chr14:75390232 RPS6KL1 0.56 4.9 0.4 2.96e-6 Coronary artery disease; TGCT cis rs651907 0.557 rs1031710 chr3:101463895 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.21 0.68 3.89e-18 Colorectal cancer; TGCT trans rs4819388 0.915 rs4818892 chr21:45650085 A/G cg17383793 chr5:52405638 MOCS2 0.67 6.74 0.52 5.21e-10 Celiac disease; TGCT cis rs8070624 0.549 rs60073596 chr17:17870974 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.28 0.55 3.28e-11 Total body bone mineral density; TGCT cis rs9394841 0.620 rs9462746 chr6:41816279 T/A cg08135965 chr6:41755394 TOMM6 0.51 4.71 0.39 6.65e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs8032315 0.965 rs7497304 chr15:91429176 G/T cg03209642 chr15:91427605 FES 0.52 4.96 0.41 2.23e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1005277 0.505 rs200931 chr10:38128434 A/C cg13531842 chr10:38383804 ZNF37A -0.39 -4.54 -0.38 1.3e-5 Extrinsic epigenetic age acceleration; TGCT trans rs6089829 0.926 rs1060489 chr20:61665921 C/T cg23505145 chr19:12996616 KLF1 0.79 8.07 0.59 5.16e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs12039431 0.666 rs215207 chr1:37952524 C/A cg17933807 chr1:38061675 GNL2 -0.76 -7.21 -0.54 4.81e-11 Epithelial ovarian cancer; TGCT cis rs9911578 1.000 rs1267545 chr17:56646909 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs174479 0.677 rs174456 chr11:61656182 G/T cg19610905 chr11:61596333 FADS2 0.55 4.7 0.39 6.94e-6 Sphingolipid levels; TGCT cis rs7666738 0.830 rs2865990 chr4:99067399 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6912958 0.559 rs499373 chr6:88042062 A/T cg08069147 chr6:88032118 GJB7;C6orf162 0.7 7.16 0.54 6.1e-11 Monocyte percentage of white cells; TGCT cis rs9486719 1.000 rs12207570 chr6:96987884 A/C cg06623918 chr6:96969491 KIAA0776 -0.96 -8.5 -0.61 5.01e-14 Migraine;Coronary artery disease; TGCT cis rs7818688 0.697 rs11781757 chr8:95987891 A/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs6456156 0.565 rs6921588 chr6:167494397 G/T cg07741184 chr6:167504864 NA 0.23 4.66 0.39 7.93e-6 Primary biliary cholangitis; TGCT cis rs4509693 0.943 rs6584395 chr10:102498008 G/C cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs2060793 0.741 rs7119073 chr11:14690962 G/A cg00085434 chr11:14927489 NA 0.34 4.67 0.39 7.64e-6 Vitamin D levels; TGCT cis rs1971762 0.730 rs7963016 chr12:54072819 T/A cg16917193 chr12:54089295 NA 0.6 4.81 0.4 4.22e-6 Height; TGCT cis rs7511006 0.895 rs5771270 chr22:50682865 G/A cg16473166 chr22:50639996 SELO 0.63 6.17 0.48 8.91e-9 Obesity-related traits; TGCT cis rs10256972 0.758 rs7799391 chr7:1082566 C/G cg03188948 chr7:1209495 NA 0.42 5.5 0.44 2.08e-7 Longevity;Endometriosis; TGCT cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs1577917 0.958 rs9647601 chr6:86449827 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.4 -0.44 3.28e-7 Response to antipsychotic treatment; TGCT cis rs1941023 0.584 rs2233253 chr11:60157166 C/T cg08716584 chr11:60157161 MS4A7 -0.35 -5.29 -0.43 5.3e-7 Congenital heart disease (maternal effect); TGCT cis rs3733631 1.000 rs1482582 chr4:104651553 A/C cg24090629 chr4:104641072 TACR3 -0.77 -6.29 -0.49 4.9e-9 Menarche (age at onset); TGCT cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg01719998 chr16:89642051 CPNE7 -0.47 -4.66 -0.39 7.91e-6 Vitiligo; TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg04389838 chr3:44770851 ZNF501 -0.41 -5.58 -0.45 1.42e-7 Depressive symptoms; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg24846343 chr22:24311635 DDTL -0.23 -5.85 -0.46 4.19e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs854765 0.547 rs4643387 chr17:17972973 C/T cg04398451 chr17:18023971 MYO15A -0.31 -4.91 -0.4 2.83e-6 Total body bone mineral density; TGCT cis rs858239 0.600 rs6967419 chr7:23136310 C/T cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7666738 0.830 rs13110903 chr4:98946373 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10056811 0.538 rs4703645 chr5:74361140 A/G cg19683494 chr5:74908142 NA 0.62 5.05 0.41 1.52e-6 Coronary artery disease; TGCT cis rs7917772 0.582 rs7922780 chr10:104401203 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.26 -0.43 6.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs921968 0.613 rs2303566 chr2:219557738 C/T cg02176678 chr2:219576539 TTLL4 -0.33 -4.46 -0.37 1.81e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs1783925 1.000 rs1615640 chr11:125308076 C/G cg03464685 chr11:125439445 EI24 0.64 5.38 0.44 3.5e-7 Formal thought disorder in schizophrenia; TGCT trans rs208515 0.525 rs10755508 chr6:66675790 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.92 10.09 0.67 7.45e-18 Exhaled nitric oxide levels; TGCT cis rs600231 0.665 rs2846861 chr11:65222305 A/G cg11802864 chr11:65308245 LTBP3 0.45 4.64 0.38 8.62e-6 Bone mineral density; TGCT trans rs1496653 0.557 rs34758087 chr3:23407872 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2688608 0.592 rs10762563 chr10:75524802 C/A cg04320760 chr10:75533139 FUT11 -0.38 -5.99 -0.47 2.06e-8 Inflammatory bowel disease; TGCT cis rs7523273 0.606 rs2796262 chr1:207915180 G/A cg22525895 chr1:207977042 MIR29B2 0.56 9.36 0.64 4.46e-16 Schizophrenia; TGCT cis rs433598 0.734 rs163276 chr16:20671546 C/T cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -5.05 -0.41 1.52e-6 Schizophrenia; TGCT cis rs17601876 0.807 rs10519299 chr15:51551346 C/G cg19946085 chr15:51559439 CYP19A1 -0.32 -4.81 -0.4 4.33e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs514406 0.825 rs9661082 chr1:53245472 A/T cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs1667284 0.967 rs895888 chr18:29228187 A/G cg15259973 chr18:29078565 DSG2 0.52 5.0 0.41 1.91e-6 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs11105298 0.891 rs11105309 chr12:89909850 T/C cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6570726 0.577 rs9497315 chr6:145791967 C/T cg05347473 chr6:146136440 FBXO30 -0.62 -5.75 -0.46 6.64e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs611744 0.647 rs864166 chr8:109249300 C/G cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs10782582 0.522 rs12125933 chr1:76130920 C/T cg03433033 chr1:76189801 ACADM -0.64 -7.32 -0.55 2.78e-11 Daytime sleep phenotypes; TGCT cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg05785598 chr3:49045655 WDR6 0.36 4.78 0.39 4.78e-6 Menarche (age at onset); TGCT cis rs2594989 0.790 rs2454491 chr3:11514290 A/G cg00170343 chr3:11313890 ATG7 0.66 5.16 0.42 9.52e-7 Circulating chemerin levels; TGCT cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg23205692 chr1:25664452 TMEM50A 0.53 5.46 0.44 2.5e-7 Erythrocyte sedimentation rate; TGCT cis rs910316 1.000 rs4903275 chr14:75512509 C/T cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.32e-6 Height; TGCT cis rs7809950 0.817 rs2712195 chr7:107127496 C/T cg23024343 chr7:107201750 COG5 -0.46 -6.9 -0.53 2.4e-10 Coronary artery disease; TGCT cis rs2762353 0.574 rs4409177 chr6:25694491 T/G cg03264133 chr6:25882463 NA 0.9 9.01 0.63 3.08e-15 Blood metabolite levels; TGCT cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg27286337 chr10:134555280 INPP5A 0.41 4.9 0.4 2.97e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7100689 0.646 rs7092237 chr10:82165640 A/G cg01528321 chr10:82214614 TSPAN14 0.72 7.8 0.57 2.13e-12 Post bronchodilator FEV1; TGCT cis rs950169 0.541 rs10795 chr15:85177297 G/A cg11189052 chr15:85197271 WDR73 0.73 6.01 0.47 1.96e-8 Schizophrenia; TGCT cis rs7666738 0.791 rs7678564 chr4:99057341 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 0.874 rs208512 chr6:66943869 C/G cg07460842 chr6:66804631 NA -0.9 -9.15 -0.63 1.45e-15 Exhaled nitric oxide output; TGCT cis rs1042058 0.565 rs2480297 chr10:30754512 A/G cg13289132 chr10:30722225 MAP3K8 -0.41 -4.86 -0.4 3.54e-6 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs7647973 0.588 rs62262675 chr3:49673662 A/G cg05785598 chr3:49045655 WDR6 -0.44 -5.19 -0.42 8.17e-7 Menarche (age at onset); TGCT cis rs9517320 0.515 rs4771307 chr13:99221879 A/G cg07423050 chr13:99094983 FARP1 -0.23 -4.5 -0.37 1.53e-5 Longevity; TGCT cis rs6835098 0.924 rs13125240 chr4:174151619 T/C cg08422745 chr4:174089978 GALNT7 0.9 10.24 0.68 3.33e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs2153535 0.580 rs4960412 chr6:8438261 G/C cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.44 4.95 0.41 2.33e-6 Lymphocyte counts; TGCT cis rs35306767 0.761 rs11253537 chr10:1010735 G/A cg26597838 chr10:835615 NA 0.57 6.42 0.5 2.6e-9 Eosinophil percentage of granulocytes; TGCT cis rs9653442 0.545 rs4850921 chr2:100762699 G/T cg07810366 chr2:100720526 AFF3 -0.38 -5.5 -0.44 2.04e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.99 -7.36 -0.55 2.25e-11 Gut microbiome composition (summer); TGCT cis rs2204008 0.605 rs4608149 chr12:38132057 G/C cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT cis rs12477438 0.501 rs13033012 chr2:99795149 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs796364 0.616 rs7574313 chr2:200681040 C/G cg17644776 chr2:200775616 C2orf69 0.35 4.96 0.41 2.29e-6 Schizophrenia; TGCT cis rs7412746 0.658 rs6677420 chr1:150946490 G/A cg04414720 chr1:150670196 GOLPH3L 0.38 4.54 0.38 1.3e-5 Melanoma; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg01802117 chr1:53393560 SCP2 0.44 5.43 0.44 2.87e-7 Monocyte count; TGCT cis rs2836974 0.931 rs13625 chr21:40669083 G/T cg11890956 chr21:40555474 PSMG1 1.1 12.28 0.74 3.66e-23 Cognitive function; TGCT cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg21171335 chr12:122356390 WDR66 0.6 6.57 0.51 1.22e-9 Mean corpuscular volume; TGCT cis rs7647973 0.925 rs6808036 chr3:49236439 T/G cg07636037 chr3:49044803 WDR6 0.63 5.09 0.42 1.27e-6 Menarche (age at onset); TGCT cis rs1971762 0.527 rs6580950 chr12:53926656 T/A cg16917193 chr12:54089295 NA 1.02 10.39 0.68 1.44e-18 Height; TGCT cis rs13102973 0.932 rs13112935 chr4:135829379 T/C cg14419869 chr4:135874104 NA 0.24 4.52 0.38 1.4e-5 Subjective well-being; TGCT cis rs6463523 0.898 rs66892628 chr7:759374 T/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.74 10.68 0.69 2.83e-19 Subjective well-being; TGCT cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg22105103 chr4:187893119 NA -0.35 -5.03 -0.41 1.66e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6725041 0.547 rs6753945 chr2:213204574 T/C cg20637307 chr2:213403960 ERBB4 -0.53 -4.5 -0.37 1.52e-5 QT interval (ambient particulate matter interaction); TGCT cis rs12142240 0.660 rs72885163 chr1:46807117 C/A cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs6940116 1 rs6940116 chr6:27708732 A/G cg10876282 chr6:28092338 ZSCAN16 0.65 4.92 0.4 2.71e-6 Intelligence (multi-trait analysis);Autism spectrum disorder or schizophrenia; TGCT cis rs17108533 0.588 rs12886355 chr14:71301165 C/T cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs1153858 1.000 rs11852800 chr15:45639131 A/G cg26924012 chr15:45694286 SPATA5L1 -1.08 -14.12 -0.79 1.39e-27 Homoarginine levels; TGCT cis rs1372520 0.684 rs2737030 chr4:90710099 C/T cg14346243 chr4:90757452 SNCA -0.65 -5.57 -0.45 1.48e-7 Neuroticism; TGCT cis rs12497850 0.931 rs28642807 chr3:48926816 A/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs7666738 0.830 rs13140676 chr4:98804978 C/T cg17366294 chr4:99064904 C4orf37 0.65 6.79 0.52 4.13e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4242434 0.597 rs11985023 chr8:22531463 C/T cg21658235 chr8:22456391 C8orf58 -0.46 -4.81 -0.4 4.37e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs13256369 0.951 rs13270852 chr8:8566853 A/G cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs67072384 1.000 rs2365441 chr11:72450226 T/C cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs7659604 0.676 rs6855269 chr4:122697418 T/G cg20573242 chr4:122745356 CCNA2 0.55 4.94 0.41 2.49e-6 Type 2 diabetes; TGCT cis rs6964587 1.000 rs6960867 chr7:91712698 A/G cg17063962 chr7:91808500 NA 0.86 9.13 0.63 1.62e-15 Breast cancer; TGCT cis rs1865760 0.713 rs6928951 chr6:25995554 C/T cg17042849 chr6:26104293 HIST1H4C -0.55 -4.8 -0.4 4.4e-6 Height; TGCT cis rs6690583 0.623 rs12033900 chr1:85478559 T/C cg20280350 chr1:85513789 MCOLN3 -0.71 -4.68 -0.39 7.31e-6 Serum sulfate level; TGCT cis rs11754661 1.000 rs11755145 chr6:151207249 G/A cg01354656 chr6:151411710 MTHFD1L 0.48 4.46 0.37 1.81e-5 Alzheimer's disease (late onset); TGCT cis rs2180341 0.597 rs3798859 chr6:127663116 C/T cg27446573 chr6:127587934 RNF146 0.66 5.9 0.47 3.23e-8 Breast cancer; TGCT cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 7.02 0.53 1.29e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12142240 0.621 rs66828173 chr1:46818166 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs3935685 0.845 rs7175083 chr15:78006842 T/C cg25212270 chr15:78015279 NA 0.26 5.45 0.44 2.63e-7 Intelligence (multi-trait analysis); TGCT cis rs12926788 0.542 rs11862971 chr16:24767574 C/A cg06028605 chr16:24865363 SLC5A11 0.41 4.58 0.38 1.13e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs172166 0.694 rs1225716 chr6:28113746 A/C cg10876282 chr6:28092338 ZSCAN16 0.49 4.53 0.38 1.37e-5 Cardiac Troponin-T levels; TGCT cis rs4455778 0.580 rs7796581 chr7:49124966 C/T cg26309511 chr7:48887640 NA 0.51 6.62 0.51 9.97e-10 Lung cancer in never smokers; TGCT cis rs7914558 0.966 rs7096269 chr10:104736721 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.97 -0.41 2.21e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7698623 0.850 rs4693194 chr4:88798005 T/C cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs9859260 0.555 rs9877493 chr3:195832147 T/C cg06252355 chr3:195477915 MUC4 -0.2 -4.53 -0.38 1.34e-5 Mean corpuscular volume; TGCT cis rs9467711 0.606 rs9379854 chr6:26362854 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs3770081 1.000 rs12328085 chr2:86262009 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -1.18 -4.81 -0.4 4.33e-6 Facial emotion recognition (sad faces); TGCT cis rs7959452 0.640 rs10878957 chr12:69699638 G/C cg20891283 chr12:69753455 YEATS4 0.66 6.57 0.51 1.24e-9 Blood protein levels; TGCT cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -8.31 -0.6 1.43e-13 Platelet count; TGCT cis rs1420338 0.967 rs1014581 chr7:34164677 T/G cg01275685 chr7:34179230 BMPER -0.26 -4.87 -0.4 3.28e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs6951245 0.935 rs11766669 chr7:1063593 C/T cg03188948 chr7:1209495 NA 0.55 4.56 0.38 1.2e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs595982 0.527 rs56021835 chr19:49369989 G/A cg17863274 chr19:49399704 TULP2 -0.47 -6.78 -0.52 4.43e-10 Red cell distribution width; TGCT cis rs651907 0.535 rs11714444 chr3:101513682 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs694739 0.536 rs11231740 chr11:64046641 C/T cg02228329 chr11:64053129 BAD;GPR137 -0.57 -5.11 -0.42 1.2e-6 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs36051895 0.697 rs11788790 chr9:5092263 G/T cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs3806843 0.551 rs184996 chr5:140323773 T/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9913156 0.793 rs72835644 chr17:4573667 G/A cg23387401 chr17:4582204 PELP1 0.32 4.7 0.39 6.8e-6 Lymphocyte counts; TGCT cis rs9325144 0.671 rs7486919 chr12:38767997 A/G cg26384229 chr12:38710491 ALG10B -0.62 -5.77 -0.46 5.9e-8 Morning vs. evening chronotype; TGCT cis rs7681440 0.746 rs6812192 chr4:90817848 A/G cg20003494 chr4:90757398 SNCA -0.48 -4.56 -0.38 1.22e-5 Dementia with Lewy bodies; TGCT cis rs79349575 0.783 rs62078370 chr17:47026836 G/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT trans rs1814175 0.817 rs12295885 chr11:50036762 T/G cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs801193 1.000 rs2420824 chr7:66131116 G/A cg00343986 chr7:65444356 GUSB -0.22 -4.87 -0.4 3.37e-6 Aortic root size; TGCT cis rs7095607 0.606 rs7913133 chr10:69961470 A/G cg18986048 chr10:69913749 MYPN 0.54 5.52 0.44 1.93e-7 Lung function (FVC); TGCT cis rs13256369 0.851 rs11786125 chr8:8564570 T/G cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT trans rs9295123 0.931 rs13212914 chr6:160570624 C/T cg22927510 chr22:50968328 TYMP -0.52 -6.96 -0.53 1.76e-10 Blood protein levels; TGCT cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg21724239 chr8:58056113 NA 0.48 5.18 0.42 8.86e-7 Developmental language disorder (linguistic errors); TGCT cis rs801193 1.000 rs1553610 chr7:66197233 T/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs7474896 0.583 rs12776092 chr10:38015795 G/C cg25427524 chr10:38739819 LOC399744 -0.34 -5.37 -0.43 3.8e-7 Obesity (extreme); TGCT cis rs7829975 0.714 rs60315134 chr8:8670599 A/G cg15556689 chr8:8085844 FLJ10661 0.66 6.07 0.48 1.47e-8 Mood instability; TGCT trans rs3774749 0.565 rs2188151 chr3:50201924 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.78 -7.58 -0.56 6.84e-12 Intelligence (multi-trait analysis); TGCT cis rs11758351 0.518 rs79922979 chr6:26224975 A/G cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.66 -4.75 -0.39 5.57e-6 Gout;Renal underexcretion gout; TGCT cis rs7246657 0.943 rs28373708 chr19:37976659 C/T cg18154014 chr19:37997991 ZNF793 0.69 4.74 0.39 5.82e-6 Coronary artery calcification; TGCT cis rs4478858 0.684 rs10753245 chr1:31731208 A/G cg07478791 chr1:31886160 SERINC2 -0.49 -4.84 -0.4 3.78e-6 Alcohol dependence; TGCT cis rs4700695 0.614 rs446618 chr5:65210062 G/A cg21114390 chr5:65439923 SFRS12 0.62 4.44 0.37 1.99e-5 Facial morphology (factor 19); TGCT cis rs45509595 0.841 rs2747054 chr6:27783359 A/G cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.24e-6 Breast cancer; TGCT cis rs9467773 0.901 rs1407045 chr6:26476155 A/G cg15659132 chr6:26577336 NA 0.64 7.01 0.53 1.33e-10 Intelligence (multi-trait analysis); TGCT trans rs916888 0.610 rs199453 chr17:44800946 C/T cg10053473 chr17:62856997 LRRC37A3 -0.4 -6.92 -0.53 2.12e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3008870 1.000 rs3008874 chr1:67431365 A/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs7267979 1.000 rs2482943 chr20:25380593 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.73e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9660992 0.542 rs17345153 chr1:205179997 A/G cg00857998 chr1:205179979 DSTYK 0.49 4.58 0.38 1.13e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs9811920 0.965 rs9849632 chr3:99867211 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.42 -4.79 -0.4 4.69e-6 Axial length; TGCT cis rs12541335 0.639 rs4871994 chr8:22206038 G/A cg09517075 chr8:22133004 PIWIL2 0.24 4.77 0.39 5.13e-6 Hypertriglyceridemia; TGCT cis rs1801239 1.000 rs77744173 chr10:16938271 T/G cg00939682 chr10:16933505 CUBN 0.48 4.49 0.37 1.59e-5 Urinary albumin-to-creatinine ratio in non-diabetics;Urinary albumin excretion; TGCT cis rs6750047 0.541 rs162330 chr2:38319496 C/A cg07380506 chr2:38303506 CYP1B1 0.57 5.34 0.43 4.34e-7 Cutaneous malignant melanoma;Melanoma; TGCT trans rs9929218 0.551 rs2296408 chr16:68713823 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.6 -7.92 -0.58 1.15e-12 Colorectal cancer; TGCT cis rs2067615 0.579 rs6539283 chr12:107222989 C/T cg15890332 chr12:107067104 RFX4 0.29 5.79 0.46 5.36e-8 Heart rate; TGCT cis rs9859260 0.710 rs34906439 chr3:195779706 A/G cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg08048268 chr3:133502702 NA -0.53 -7.17 -0.54 5.89e-11 Iron status biomarkers; TGCT cis rs13217239 0.646 rs6937880 chr6:27000236 C/T cg05738196 chr6:26577821 NA 0.49 4.75 0.39 5.45e-6 Schizophrenia; TGCT cis rs9300255 0.739 rs6633 chr12:123745809 G/T cg00376283 chr12:123451042 ABCB9 -0.72 -4.96 -0.41 2.22e-6 Neutrophil percentage of white cells; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg15242686 chr22:24348715 GSTTP1 0.44 5.98 0.47 2.23e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs751728 1.000 rs755496 chr6:33734376 C/G cg13859433 chr6:33739653 LEMD2 -0.4 -7.63 -0.57 5.49e-12 Crohn's disease; TGCT cis rs1050631 1.000 rs1789504 chr18:33696772 A/C cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.95 0.41 2.37e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs67311347 1.000 rs1123019 chr3:40488280 C/T cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs28595532 0.920 rs114051506 chr4:119772893 A/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT trans rs11088226 0.681 rs2833911 chr21:33949629 C/T cg09050820 chr6:167586206 TCP10L2 -0.76 -7.23 -0.54 4.36e-11 Gastritis; TGCT trans rs6089829 0.962 rs1116450 chr20:61658210 T/C cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2637266 0.703 rs4376842 chr10:78456250 C/T cg18941641 chr10:78392320 NA 0.4 4.94 0.41 2.52e-6 Pulmonary function; TGCT cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg07424592 chr7:64974309 NA 1.51 8.49 0.61 5.38e-14 Diabetic kidney disease; TGCT trans rs1496653 0.602 rs71322195 chr3:23558386 T/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs477895 0.938 rs28395875 chr11:64024048 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.32 0.43 4.6e-7 Mean platelet volume; TGCT cis rs9443645 0.901 rs1542977 chr6:79550307 G/T cg05283184 chr6:79620031 NA -0.21 -4.77 -0.39 5.1e-6 Intelligence (multi-trait analysis); TGCT cis rs9640161 0.789 rs3735174 chr7:150020489 T/C cg17279839 chr7:150038598 RARRES2 0.44 4.69 0.39 7.22e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg26531700 chr6:26746687 NA 0.51 4.61 0.38 9.86e-6 Intelligence (multi-trait analysis); TGCT cis rs12530845 0.561 rs73725182 chr7:135291001 C/T cg23117316 chr7:135346802 PL-5283 -0.6 -5.42 -0.44 2.93e-7 Red blood cell traits; TGCT cis rs853679 0.517 rs4713150 chr6:28136212 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs10791097 0.967 rs4366492 chr11:130717256 T/C cg12179176 chr11:130786555 SNX19 0.63 6.63 0.51 9.22e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs362272 0.545 rs2749782 chr4:3339761 A/G cg22655196 chr4:3374909 RGS12 0.23 4.69 0.39 7.14e-6 Serum sulfate level; TGCT cis rs4975709 0.589 rs1466607 chr5:1864856 A/G cg07747251 chr5:1868357 NA 0.39 5.78 0.46 5.58e-8 Cardiovascular disease risk factors; TGCT cis rs17270561 0.541 rs17586946 chr6:25939053 C/T cg17691542 chr6:26056736 HIST1H1C 0.87 5.92 0.47 2.89e-8 Iron status biomarkers; TGCT cis rs2295359 0.643 rs1569922 chr1:67664963 C/T cg12940439 chr1:67600707 NA 0.44 4.6 0.38 1.03e-5 Psoriasis; TGCT cis rs11190604 1.000 rs10883493 chr10:102208188 A/T cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7412746 0.658 rs6657388 chr1:150748786 A/G cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs66573146 1.000 rs66519732 chr4:6990569 C/G cg01220768 chr4:7056774 TADA2B 0.39 4.93 0.41 2.54e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1997103 0.906 rs6593232 chr7:55402916 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg01802117 chr1:53393560 SCP2 -0.43 -5.2 -0.42 8.03e-7 Monocyte count; TGCT cis rs861020 0.771 rs661849 chr1:210001233 C/T cg05527609 chr1:210001259 C1orf107 1.03 9.02 0.63 2.96e-15 Orofacial clefts; TGCT cis rs1670533 1.000 rs2290408 chr4:1067267 A/C cg27284194 chr4:1044797 NA -0.69 -6.02 -0.48 1.83e-8 Recombination rate (females); TGCT cis rs11971779 0.584 rs6962029 chr7:139034719 T/C cg07862535 chr7:139043722 LUC7L2 0.56 4.46 0.37 1.82e-5 Diisocyanate-induced asthma; TGCT cis rs2224391 0.955 rs2773322 chr6:5263065 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.75 -5.62 -0.45 1.2e-7 Height; TGCT cis rs9302065 1.000 rs7490267 chr13:95970258 T/C cg24476569 chr13:95954382 ABCC4 -0.44 -6.46 -0.5 2.15e-9 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs801193 1.000 rs17566701 chr7:66193183 T/C cg00343986 chr7:65444356 GUSB 0.21 4.58 0.38 1.12e-5 Aortic root size; TGCT cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg13342137 chr4:2252803 MXD4 0.17 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs1887596 0.624 rs9553858 chr13:27138472 A/G cg01312412 chr13:27282625 NA -0.29 -5.19 -0.42 8.24e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs807669 0.903 rs2800974 chr22:19168087 C/T cg02655711 chr22:19163373 SLC25A1 0.42 10.06 0.67 8.99e-18 Metabolite levels; TGCT cis rs11716531 0.573 rs642570 chr3:27342595 C/G cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Diastolic blood pressure; TGCT cis rs739401 0.572 rs12276060 chr11:3015572 A/T cg25174290 chr11:3078921 CARS 0.5 4.68 0.39 7.28e-6 Longevity; TGCT cis rs2469997 0.925 rs2470015 chr8:120360969 T/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs7674212 0.507 rs6843738 chr4:103936001 G/A cg16532752 chr4:104119610 CENPE -0.59 -5.26 -0.43 6.21e-7 Type 2 diabetes; TGCT cis rs2301573 1.000 rs10934888 chr3:129307191 C/T cg07730360 chr3:128845626 NA 0.33 4.61 0.38 9.84e-6 Hip circumference; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.57 -5.22 -0.42 7.14e-7 Prudent dietary pattern; TGCT cis rs2463822 0.614 rs117699706 chr11:62161659 T/C cg06239285 chr11:62104954 ASRGL1 -0.85 -5.54 -0.45 1.76e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2777491 0.874 rs28716108 chr15:41655523 G/C cg18705301 chr15:41695430 NDUFAF1 -0.72 -10.33 -0.68 1.94e-18 Ulcerative colitis; TGCT cis rs7255374 0.566 rs7255904 chr19:41529020 C/T cg20630647 chr19:41531805 NA 0.37 6.41 0.5 2.73e-9 DDT metabolite (p,p'-DDE levels); TGCT cis rs1150668 0.796 rs9468372 chr6:28379361 T/A cg19488431 chr6:28601329 NA 0.21 4.61 0.38 9.84e-6 Pubertal anthropometrics; TGCT cis rs7772486 0.534 rs34541797 chr6:146205304 A/G cg05347473 chr6:146136440 FBXO30 0.64 6.06 0.48 1.48e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2204008 0.660 rs2320745 chr12:38239101 T/C cg13010199 chr12:38710504 ALG10B 0.59 4.54 0.38 1.29e-5 Bladder cancer; TGCT cis rs6500550 0.605 rs2285813 chr16:3566102 C/A cg07396092 chr16:3662230 BTBD12 0.53 4.54 0.38 1.31e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;White blood cell count;Neutrophil count; TGCT cis rs11648796 0.765 rs2003832 chr16:769538 G/A cg00908189 chr16:619842 PIGQ 0.81 6.47 0.5 2.06e-9 Height; TGCT cis rs9926296 0.682 rs258328 chr16:89730314 C/T cg27121462 chr16:89883253 FANCA -0.54 -5.01 -0.41 1.83e-6 Vitiligo; TGCT cis rs9611565 0.592 rs6519270 chr22:42078666 A/G cg17554472 chr22:41940697 POLR3H 0.47 5.06 0.41 1.46e-6 Vitiligo; TGCT cis rs1971762 0.563 rs10747679 chr12:54077750 C/T cg16917193 chr12:54089295 NA 1.37 17.65 0.85 1.25e-35 Height; TGCT cis rs514406 0.861 rs12038438 chr1:53230581 A/T cg01802117 chr1:53393560 SCP2 0.42 5.11 0.42 1.2e-6 Monocyte count; TGCT cis rs7949030 0.626 rs7930896 chr11:62325272 A/G cg13298116 chr11:62369859 EML3;MTA2 0.63 9.2 0.64 1.08e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11172134 0.508 rs11837145 chr12:57570014 C/A cg19258868 chr12:57585184 LRP1 -0.31 -5.68 -0.45 9.21e-8 Urate levels in overweight individuals; TGCT cis rs951366 0.903 rs823114 chr1:205719532 G/A cg07157834 chr1:205819609 PM20D1 0.34 5.01 0.41 1.81e-6 Menarche (age at onset); TGCT cis rs7843479 0.965 rs1564305 chr8:21803816 A/C cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs826838 1.000 rs1095575 chr12:39110284 C/G cg26384229 chr12:38710491 ALG10B -0.87 -8.02 -0.58 6.78e-13 Heart rate; TGCT cis rs7635838 0.819 rs4684781 chr3:11516299 G/A cg00170343 chr3:11313890 ATG7 0.69 6.66 0.51 8.06e-10 HDL cholesterol; TGCT cis rs2842992 0.789 rs9355748 chr6:160194882 G/A cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs9486719 1.000 rs2145535 chr6:97034715 G/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs66573146 1.000 rs56074877 chr4:6990374 C/T cg00086871 chr4:6988644 TBC1D14 0.94 4.62 0.38 9.61e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7666738 0.791 rs10856934 chr4:99010844 A/G cg05340658 chr4:99064831 C4orf37 -0.47 -5.02 -0.41 1.77e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs769267 0.965 rs8101938 chr19:19390497 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs4665809 0.590 rs6716858 chr2:26423414 G/A cg26119090 chr2:26468346 HADHA;HADHB -0.93 -6.86 -0.52 2.86e-10 Gut microbiome composition (summer); TGCT cis rs644799 0.710 rs56384142 chr11:95502075 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.29 0.6 1.54e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs675209 0.525 rs4960296 chr6:7208840 A/T cg27097018 chr6:6320614 F13A1 0.37 5.35 0.43 4.04e-7 Urate levels; TGCT cis rs6964587 1.000 rs6976122 chr7:91610962 T/C cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs13118159 0.778 rs12650998 chr4:1338832 T/C cg22683308 chr4:1340831 KIAA1530 -0.66 -6.17 -0.48 8.75e-9 Longevity; TGCT cis rs4372836 0.729 rs10166861 chr2:29061111 A/G cg09522027 chr2:28974177 PPP1CB -0.7 -7.28 -0.55 3.39e-11 Body mass index; TGCT cis rs7267979 0.966 rs6050532 chr20:25308793 A/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9549367 0.789 rs12866090 chr13:113869410 G/A cg18105134 chr13:113819100 PROZ -0.35 -5.68 -0.45 8.89e-8 Platelet distribution width; TGCT cis rs2227564 0.574 rs3849969 chr10:75525999 C/T cg04320760 chr10:75533139 FUT11 0.33 4.67 0.39 7.82e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1150668 0.830 rs2023493 chr6:28400162 T/C cg13525197 chr6:28411240 ZSCAN23 -0.51 -4.93 -0.4 2.6e-6 Pubertal anthropometrics; TGCT cis rs270601 0.721 rs270621 chr5:131605821 C/A cg12564285 chr5:131593104 PDLIM4 0.41 4.71 0.39 6.61e-6 Acylcarnitine levels; TGCT cis rs10193935 0.901 rs9789740 chr2:42486799 A/G cg27598129 chr2:42591480 NA -0.39 -5.41 -0.44 3.06e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs12220238 0.915 rs11000945 chr10:76030739 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.87 5.85 0.46 4.15e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg12311346 chr5:56204834 C5orf35 0.83 7.78 0.57 2.41e-12 Initial pursuit acceleration; TGCT cis rs4325129 1.000 rs4325129 chr1:159462381 A/G cg07417683 chr1:159440267 NA -0.45 -4.63 -0.38 9.16e-6 Obesity-related traits; TGCT cis rs2842992 0.789 rs6908680 chr6:160218209 G/T cg11366901 chr6:160182831 ACAT2 1.06 7.18 0.54 5.54e-11 Age-related macular degeneration (geographic atrophy); TGCT cis rs3902035 0.964 rs62422259 chr6:119007732 T/C cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.68e-9 Blood metabolite levels; TGCT cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7937682 0.824 rs510866 chr11:111484113 A/C cg09085632 chr11:111637200 PPP2R1B -1.06 -11.52 -0.72 2.48e-21 Primary sclerosing cholangitis; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg07332563 chr6:291687 DUSP22 -0.75 -7.62 -0.56 5.67e-12 Menopause (age at onset); TGCT cis rs873946 0.586 rs61862838 chr10:134572282 C/T cg17054783 chr10:134559939 INPP5A 0.24 4.83 0.4 3.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs13108904 0.518 rs4974603 chr4:1343168 C/T cg03303774 chr4:1407052 NA 0.36 5.5 0.44 2.08e-7 Obesity-related traits; TGCT cis rs13217239 0.646 rs10946888 chr6:26951678 A/G cg26531700 chr6:26746687 NA 0.69 6.92 0.53 2.11e-10 Schizophrenia; TGCT cis rs9467711 0.584 rs34244947 chr6:26761745 T/C cg16898833 chr6:26189333 HIST1H4D 1.27 6.03 0.48 1.76e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg11502198 chr6:26597334 ABT1 0.52 4.57 0.38 1.17e-5 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.542 rs9378553 chr6:8472632 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs909674 0.541 rs5750816 chr22:39810379 A/G cg05872129 chr22:39784769 NA 0.99 10.97 0.7 5.41e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7552404 0.731 rs7523573 chr1:76372020 G/T cg03433033 chr1:76189801 ACADM 0.74 6.98 0.53 1.58e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9467711 0.606 rs35307327 chr6:26370474 C/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs5769765 0.955 rs5770750 chr22:50276828 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.81 0.73 5.03e-22 Schizophrenia; TGCT cis rs7681440 0.874 rs1442151 chr4:90775491 T/A cg14346243 chr4:90757452 SNCA -0.56 -5.47 -0.44 2.41e-7 Dementia with Lewy bodies; TGCT cis rs12413816 0.784 rs35537139 chr10:13768894 G/A cg16485048 chr10:13749193 FRMD4A 0.26 5.36 0.43 3.99e-7 Red cell distribution width; TGCT cis rs8038465 1.000 rs8041523 chr15:73982556 C/T cg15420318 chr15:73925796 NPTN 0.69 6.4 0.5 2.86e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1218582 0.710 rs7553195 chr1:154837796 T/C cg16680214 chr1:154839983 KCNN3 -0.41 -8.75 -0.62 1.29e-14 Prostate cancer; TGCT cis rs5758343 1 rs5758343 chr22:41816652 A/T cg03806693 chr22:41940476 POLR3H 1.19 13.5 0.77 4.07e-26 Allergic disease (asthma, hay fever or eczema); TGCT cis rs736408 0.716 rs2300149 chr3:52822921 C/T cg10802521 chr3:52805072 NEK4 -0.72 -8.9 -0.62 5.64e-15 Bipolar disorder; TGCT cis rs7809950 0.678 rs7788271 chr7:106985873 A/G cg23024343 chr7:107201750 COG5 -0.43 -5.85 -0.47 4.12e-8 Coronary artery disease; TGCT cis rs734999 0.588 rs2764842 chr1:2529192 A/G cg18854424 chr1:2615690 NA -0.46 -5.23 -0.43 6.92e-7 Ulcerative colitis; TGCT cis rs11096990 0.656 rs6531710 chr4:39302278 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs2204008 0.687 rs11181339 chr12:38322271 G/T cg26384229 chr12:38710491 ALG10B 0.77 6.85 0.52 3.04e-10 Bladder cancer; TGCT cis rs912057 0.671 rs1294434 chr6:6745377 G/A cg06612196 chr6:6737390 NA 0.46 6.71 0.52 6.07e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs7666738 0.830 rs2865951 chr4:99040191 C/T cg05340658 chr4:99064831 C4orf37 0.55 6.33 0.49 4.12e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs881375 0.967 rs2416806 chr9:123690292 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.99 0.41 2.03e-6 Rheumatoid arthritis; TGCT cis rs7584330 0.518 rs74003106 chr2:238447004 A/G cg14458575 chr2:238380390 NA 0.43 4.51 0.38 1.48e-5 Prostate cancer; TGCT cis rs12188164 0.686 rs72711367 chr5:418494 A/G cg26850624 chr5:429559 AHRR -0.21 -4.98 -0.41 2.06e-6 Cystic fibrosis severity; TGCT cis rs6969780 0.722 rs985652 chr7:27198083 A/C cg04317399 chr7:27170313 HOXA4 -0.43 -4.8 -0.4 4.49e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg16325326 chr1:53192061 ZYG11B -0.85 -11.97 -0.73 1.98e-22 Monocyte count; TGCT cis rs13256369 1.000 rs13271966 chr8:8575472 T/C cg06671706 chr8:8559999 CLDN23 0.35 4.62 0.38 9.35e-6 Obesity-related traits; TGCT cis rs8056742 0.908 rs9630655 chr16:85095080 A/G cg00229868 chr16:85520891 NA 0.33 4.82 0.4 4.04e-6 Amyotrophic lateral sclerosis; TGCT cis rs7917772 0.629 rs1475646 chr10:104522564 G/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.56 -4.59 -0.38 1.07e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12497850 0.931 rs1134591 chr3:48972892 C/T cg05785598 chr3:49045655 WDR6 0.39 4.91 0.4 2.77e-6 Parkinson's disease; TGCT trans rs17471911 0.708 rs7082050 chr10:100757488 C/T cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs2188554 1.000 rs10225824 chr7:117012023 G/A cg08576598 chr7:116962626 WNT2 -0.38 -4.57 -0.38 1.14e-5 Esophageal adenocarcinoma; TGCT cis rs35883536 0.513 rs6577180 chr1:101016939 G/A cg06223162 chr1:101003688 GPR88 0.42 8.38 0.6 9.73e-14 Monocyte count; TGCT cis rs250677 0.687 rs2915809 chr5:148452111 A/T cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.05 0.41 1.51e-6 Menopause (age at onset); TGCT cis rs9906944 0.657 rs4643373 chr17:47123423 T/C cg07075026 chr17:47091521 IGF2BP1 -0.5 -5.22 -0.42 7.17e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs1008375 0.902 rs12503164 chr4:17656107 C/T cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1153858 1.000 rs11070457 chr15:45686943 A/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs597539 0.615 rs629426 chr11:68671104 A/G cg21963583 chr11:68658836 MRPL21 0.36 6.03 0.48 1.74e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12477438 0.501 rs7349217 chr2:99815146 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.04 0.76 5.31e-25 Chronic sinus infection; TGCT cis rs10504229 0.871 rs56372514 chr8:58157166 A/G cg08280861 chr8:58055591 NA 0.36 4.77 0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.580 rs1932281 chr6:8473765 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs6918586 0.658 rs198843 chr6:26110314 A/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.07e-9 Schizophrenia; TGCT cis rs7582180 0.629 rs12617779 chr2:100937707 G/A cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs2795502 0.882 rs2744093 chr10:43339243 A/G cg20628663 chr10:43360327 NA -0.44 -6.37 -0.5 3.4e-9 Blood protein levels; TGCT trans rs208520 0.690 rs207107 chr6:66794385 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs514406 0.893 rs522287 chr1:53365493 C/T cg27535305 chr1:53392650 SCP2 -0.27 -5.47 -0.44 2.39e-7 Monocyte count; TGCT cis rs7103648 0.669 rs7927445 chr11:47780754 G/T cg20307385 chr11:47447363 PSMC3 0.77 7.25 0.55 3.99e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs7474896 0.583 rs11011346 chr10:38009483 C/T cg13720705 chr10:37990370 NA 0.33 4.93 0.41 2.53e-6 Obesity (extreme); TGCT cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.27 4.81 0.4 4.38e-6 Schizophrenia; TGCT cis rs6009824 1.000 rs6009824 chr22:50086373 C/T cg27029450 chr22:50098074 NA 0.34 4.44 0.37 1.96e-5 Natriuretic peptide levels; TGCT cis rs568617 0.626 rs78028320 chr11:65582015 G/A cg04055107 chr11:65626734 MUS81;CFL1 0.6 4.82 0.4 4.15e-6 Crohn's disease; TGCT cis rs910316 0.967 rs4903292 chr14:75656245 A/G cg08847533 chr14:75593920 NEK9 0.93 10.31 0.68 2.18e-18 Height; TGCT cis rs17270561 0.779 rs12209218 chr6:25887776 C/A cg16482183 chr6:26056742 HIST1H1C 0.9 6.76 0.52 4.9e-10 Iron status biomarkers; TGCT cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg19774624 chr17:42201019 HDAC5 0.75 9.44 0.65 2.89e-16 Total body bone mineral density; TGCT cis rs62064224 0.593 rs916663 chr17:30835833 A/C cg18200150 chr17:30822561 MYO1D -0.52 -6.9 -0.53 2.43e-10 Schizophrenia; TGCT cis rs6669384 0.774 rs61821318 chr1:208033706 C/T cg22525895 chr1:207977042 MIR29B2 -0.38 -5.35 -0.43 4.04e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs854765 0.547 rs8075189 chr17:17901946 C/G cg09796270 chr17:17721594 SREBF1 0.25 5.03 0.41 1.71e-6 Total body bone mineral density; TGCT cis rs78366141 0.649 rs78179026 chr4:89657456 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.16 5.16 0.42 9.33e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT trans rs2727020 0.638 rs1164668 chr11:49330627 A/C cg03929089 chr4:120376271 NA 0.7 7.93 0.58 1.1e-12 Coronary artery disease; TGCT cis rs17152411 1.000 rs10901837 chr10:126614618 G/A cg07906193 chr10:126599966 NA 0.41 5.11 0.42 1.17e-6 Height; TGCT cis rs6570726 0.967 rs374728 chr6:145854598 T/A cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs12477438 0.520 rs11689265 chr2:99799267 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.32 0.85 4.52e-37 Chronic sinus infection; TGCT cis rs2120019 0.938 rs2120020 chr15:75316845 T/C cg09165964 chr15:75287851 SCAMP5 -1.14 -10.33 -0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs2562456 0.917 rs2681377 chr19:21716520 T/C cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs1372520 0.935 rs2245801 chr4:90757840 T/C cg01966878 chr4:90757139 SNCA -0.31 -4.67 -0.39 7.58e-6 Neuroticism; TGCT cis rs916888 0.687 rs199456 chr17:44797919 C/T cg05721485 chr17:44071124 MAPT 0.26 4.58 0.38 1.1e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs225245 0.755 rs6505491 chr17:34026335 A/G cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs9467711 0.606 rs9379863 chr6:26372427 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg06634786 chr22:41940651 POLR3H -0.88 -8.72 -0.62 1.55e-14 Vitiligo; TGCT cis rs11098499 0.779 rs80242894 chr4:120375752 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT trans rs916888 0.610 rs199438 chr17:44791643 G/A cg10053473 chr17:62856997 LRRC37A3 -0.39 -6.63 -0.51 9.28e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg07424592 chr7:64974309 NA 1.4 8.41 0.6 8.17e-14 Diabetic kidney disease; TGCT cis rs7937612 1.000 rs10790380 chr11:120233158 G/A cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.62 -0.38 9.5e-6 Intraocular pressure; TGCT cis rs568617 1.000 rs656980 chr11:65656282 G/A cg04055107 chr11:65626734 MUS81;CFL1 0.57 5.22 0.42 7.39e-7 Crohn's disease; TGCT cis rs11674184 0.714 rs9789525 chr2:11724580 G/T cg07314298 chr2:11723111 GREB1 -0.42 -7.73 -0.57 3.21e-12 Endometriosis; TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.06 13.15 0.76 2.92e-25 Prudent dietary pattern; TGCT cis rs2980439 0.525 rs2980508 chr8:8171732 C/T cg06636001 chr8:8085503 FLJ10661 0.6 5.19 0.42 8.29e-7 Neuroticism; TGCT cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs2832191 0.933 rs2832236 chr21:30547602 C/T cg08807101 chr21:30365312 RNF160 -0.51 -4.72 -0.39 6.16e-6 Dental caries; TGCT cis rs2274273 0.712 rs1002054 chr14:55528913 A/C cg01923255 chr14:55878535 KIAA0831 0.56 4.76 0.39 5.32e-6 Protein biomarker; TGCT cis rs921968 0.541 rs490483 chr2:219429052 A/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6688613 0.729 rs2072742 chr1:166929673 A/G cg07049167 chr1:166818506 POGK 0.27 5.16 0.42 9.39e-7 Refractive astigmatism; TGCT cis rs6570726 1.000 rs441477 chr6:145848243 C/T cg05347473 chr6:146136440 FBXO30 0.49 4.44 0.37 1.96e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4409675 0.576 rs11247705 chr1:28212272 G/A cg23691781 chr1:28212827 C1orf38 0.25 5.28 0.43 5.66e-7 Corneal astigmatism; TGCT cis rs7666738 0.830 rs28587201 chr4:98991733 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11148252 0.774 rs9536066 chr13:52983981 A/G cg00495681 chr13:53174319 NA 0.54 5.39 0.44 3.38e-7 Lewy body disease; TGCT cis rs904251 0.561 rs1757189 chr6:37483727 G/C cg25019722 chr6:37503610 NA -0.52 -7.86 -0.58 1.62e-12 Cognitive performance; TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg18538332 chr22:24372958 LOC391322 -0.73 -7.63 -0.57 5.45e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs208520 0.690 rs3846808 chr6:66818604 A/G cg07460842 chr6:66804631 NA -0.94 -10.0 -0.67 1.23e-17 Exhaled nitric oxide output; TGCT cis rs8072100 0.656 rs2610367 chr17:45569815 A/G cg08085267 chr17:45401833 C17orf57 -0.44 -4.78 -0.39 4.96e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9611565 0.500 rs2011053 chr22:42121278 G/A cg06634786 chr22:41940651 POLR3H 0.82 7.9 0.58 1.3e-12 Vitiligo; TGCT cis rs796364 0.951 rs3098341 chr2:200792498 G/T cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs4891159 0.570 rs690132 chr18:74117261 T/C cg24786174 chr18:74118243 ZNF516 0.71 15.66 0.82 3.6e-31 Longevity; TGCT cis rs7208859 0.673 rs216424 chr17:28943064 T/G cg04154034 chr17:28927549 LRRC37B2 0.74 4.46 0.37 1.81e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2795502 0.938 rs3121281 chr10:43400753 A/G cg20628663 chr10:43360327 NA 0.36 5.45 0.44 2.66e-7 Blood protein levels; TGCT cis rs11577318 0.796 rs4625269 chr1:26626967 C/A cg12733254 chr1:26682999 NA -0.2 -4.46 -0.37 1.79e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs9364220 0.662 rs9295044 chr6:168494289 T/G cg02770688 chr6:168491649 NA -0.31 -5.72 -0.46 7.6e-8 Attention deficit hyperactivity disorder (inattention symptoms);Attention deficit hyperactivity disorder (combined symptoms); TGCT cis rs2777491 0.872 rs7163649 chr15:41586798 A/G cg18705301 chr15:41695430 NDUFAF1 -0.74 -10.63 -0.69 3.68e-19 Ulcerative colitis; TGCT cis rs12893668 0.572 rs11540512 chr14:104147377 C/T cg26031613 chr14:104095156 KLC1 -0.59 -5.08 -0.42 1.34e-6 Reticulocyte count; TGCT cis rs12681288 0.676 rs4565481 chr8:1001944 C/T cg04851639 chr8:1020857 NA -0.32 -5.37 -0.43 3.79e-7 Schizophrenia; TGCT cis rs2288884 1.000 rs56808319 chr19:52577874 A/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.47 -0.37 1.74e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs2180341 0.804 rs6902233 chr6:127555963 A/G cg24812749 chr6:127587940 RNF146 0.92 6.46 0.5 2.18e-9 Breast cancer; TGCT cis rs7611238 0.517 rs9814344 chr3:195136047 T/G cg27323046 chr3:195102265 ACAP2 0.38 5.13 0.42 1.09e-6 Body mass index; TGCT cis rs28735056 1.000 rs56197868 chr18:77636077 C/T cg20368463 chr18:77673604 PQLC1 -0.44 -5.46 -0.44 2.44e-7 Schizophrenia; TGCT cis rs28595532 0.800 rs111626798 chr4:119352517 C/T cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg26531700 chr6:26746687 NA 0.68 6.65 0.51 8.19e-10 Schizophrenia; TGCT cis rs79387448 0.638 rs6759588 chr2:103040159 A/G cg09003973 chr2:102972529 NA 1.35 9.34 0.64 4.96e-16 Gut microbiota (bacterial taxa); TGCT cis rs6061231 0.631 rs927133 chr20:60972109 C/T cg24112000 chr20:60950667 NA -0.35 -4.88 -0.4 3.24e-6 Colorectal cancer; TGCT cis rs11098499 0.738 rs34965784 chr4:120361586 G/C cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs11785400 0.963 rs4579507 chr8:143733663 C/G cg24634471 chr8:143751801 JRK 0.56 6.12 0.48 1.13e-8 Schizophrenia; TGCT cis rs514406 0.505 rs431459 chr1:53183230 T/G cg24675658 chr1:53192096 ZYG11B -0.79 -9.7 -0.66 6.86e-17 Monocyte count; TGCT cis rs12210905 1.000 rs72843613 chr6:27138467 G/A cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs6840360 0.593 rs10016160 chr4:152693998 A/G cg22705602 chr4:152727874 NA -0.34 -5.9 -0.47 3.24e-8 Intelligence (multi-trait analysis); TGCT cis rs56104184 0.830 rs28556985 chr19:49351149 C/T cg21252483 chr19:49399788 TULP2 -0.43 -5.49 -0.44 2.2e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs877282 0.838 rs11253374 chr10:774961 C/T cg22713356 chr15:30763199 NA 1.17 10.77 0.7 1.7e-19 Uric acid levels; TGCT cis rs2282802 0.685 rs13170475 chr5:139671062 C/T cg01081189 chr5:139537190 NA 0.29 5.31 0.43 5e-7 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.533 rs1397683 chr4:152715916 T/C cg22705602 chr4:152727874 NA 0.34 5.95 0.47 2.5e-8 Intelligence (multi-trait analysis); TGCT cis rs7568458 0.905 rs6739015 chr2:85755357 A/G cg17127132 chr2:85788382 GGCX 0.72 6.69 0.51 6.94e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs644799 0.540 rs10831422 chr11:95478968 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.58 5.7 0.46 8.21e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7296418 0.663 rs11057284 chr12:123830692 G/C cg00376283 chr12:123451042 ABCB9 0.63 5.42 0.44 3.02e-7 Platelet count; TGCT trans rs2688608 0.592 rs11000759 chr10:75493726 G/A cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs28595532 0.920 rs116405053 chr4:119739352 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2204008 0.715 rs3899385 chr12:38169880 C/G cg13010199 chr12:38710504 ALG10B 0.62 4.89 0.4 3.09e-6 Bladder cancer; TGCT cis rs7666738 0.830 rs60391193 chr4:98933912 T/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12257961 0.579 rs4748160 chr10:15360718 T/A cg10616319 chr10:15468812 NA -0.25 -4.56 -0.38 1.21e-5 Selective IgA deficiency; TGCT cis rs57590327 0.555 rs3772884 chr3:81802720 G/T cg07356753 chr3:81810745 GBE1 -0.77 -7.26 -0.55 3.75e-11 Extraversion; TGCT cis rs7959452 0.532 rs2291005 chr12:69764388 A/G cg11871910 chr12:69753446 YEATS4 0.82 8.82 0.62 8.61e-15 Blood protein levels; TGCT cis rs2456568 0.805 rs2032400 chr11:93676937 G/A cg26875233 chr11:93583750 C11orf90 -0.44 -5.5 -0.44 2.05e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7552404 0.731 rs12078299 chr1:76365764 T/A cg22875332 chr1:76189707 ACADM 0.67 6.42 0.5 2.57e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2204008 0.666 rs67792345 chr12:38204698 T/C cg26384229 chr12:38710491 ALG10B 0.78 6.56 0.51 1.32e-9 Bladder cancer; TGCT cis rs2663905 0.611 rs1509560 chr15:81391713 T/G cg27045999 chr15:81426544 C15orf26 -0.55 -5.52 -0.44 1.89e-7 QT interval (drug interaction); TGCT cis rs13326165 0.715 rs11718125 chr3:52379420 T/C cg27565382 chr3:53032988 SFMBT1 0.36 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1878931 0.559 rs11643501 chr16:3392752 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.27 0.55 3.55e-11 Body mass index (adult); TGCT cis rs2816062 0.786 rs2816038 chr1:18880525 C/T cg18795169 chr1:18902165 NA -0.59 -13.16 -0.76 2.73e-25 Urate levels in lean individuals; TGCT cis rs709400 0.550 rs942865 chr14:104015250 G/A cg26031613 chr14:104095156 KLC1 0.77 6.32 0.49 4.33e-9 Body mass index; TGCT cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs2013441 1.000 rs2243732 chr17:20088589 C/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs17122693 0.748 rs7159861 chr14:51144660 C/T cg04730355 chr14:51134070 SAV1 -1.23 -10.96 -0.7 5.87e-20 Cognitive performance; TGCT cis rs7267979 1.000 rs4815407 chr20:25341478 G/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4919694 0.808 rs77521106 chr10:104980726 G/T cg04362960 chr10:104952993 NT5C2 1.09 7.26 0.55 3.68e-11 Arsenic metabolism; TGCT cis rs3733585 0.664 rs17185870 chr4:9958214 C/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.68 -0.51 7.16e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7845219 0.525 rs7820818 chr8:95919231 G/A cg09323728 chr8:95962352 TP53INP1 -0.41 -4.57 -0.38 1.17e-5 Type 2 diabetes; TGCT cis rs2239547 0.522 rs9311485 chr3:52987645 T/G cg11645453 chr3:52864694 ITIH4 -0.32 -5.32 -0.43 4.67e-7 Schizophrenia; TGCT cis rs7412746 0.586 rs2864882 chr1:150883037 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs7582180 0.652 rs11694700 chr2:100936637 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs936229 0.768 rs12442901 chr15:75083912 A/G cg10253484 chr15:75165896 SCAMP2 -0.65 -5.12 -0.42 1.15e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs9303401 0.580 rs12603808 chr17:56578508 T/G cg10487724 chr17:56770010 TEX14;RAD51C 0.71 6.78 0.52 4.45e-10 Cognitive test performance; TGCT cis rs9362426 0.639 rs35332886 chr6:88141064 A/G cg10919329 chr6:88182879 SLC35A1 -0.61 -4.63 -0.38 9.03e-6 Depressive episodes in bipolar disorder; TGCT cis rs9399135 1.000 rs4475342 chr6:135283348 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.79 0.39 4.75e-6 Red blood cell count; TGCT cis rs9393777 0.513 rs9368450 chr6:26652489 A/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg11845111 chr2:191398756 TMEM194B 0.37 5.65 0.45 1.03e-7 Pulse pressure; TGCT cis rs4788570 0.578 rs4788553 chr16:71780277 T/G cg06353428 chr16:71660113 MARVELD3 1.56 12.67 0.75 4.05e-24 Intelligence (multi-trait analysis); TGCT cis rs1801251 0.963 rs7591176 chr2:233581803 C/A cg25237894 chr2:233734115 C2orf82 0.33 6.02 0.48 1.85e-8 Coronary artery disease; TGCT cis rs6882046 0.513 rs587490 chr5:88032522 C/T cg22951263 chr5:87985283 NA -0.55 -5.94 -0.47 2.74e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs12791968 0.917 rs11038239 chr11:45002012 A/G cg11846598 chr11:44996168 LOC221122 -0.35 -6.45 -0.5 2.29e-9 Inhibitory control; TGCT cis rs6088580 0.634 rs6120666 chr20:33090718 A/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs2486012 1.000 rs2428953 chr1:44443459 G/A cg12908607 chr1:44402522 ARTN 0.67 5.9 0.47 3.17e-8 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs73080165 chr3:40533062 G/T cg13683864 chr3:40499215 RPL14 -1.17 -11.19 -0.71 1.56e-20 Renal cell carcinoma; TGCT cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.63 6.65 0.51 8.58e-10 Height; TGCT cis rs514406 0.861 rs554760 chr1:53266749 G/A cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs17376456 0.877 rs17083462 chr5:93462401 T/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg13695892 chr22:41940480 POLR3H -0.91 -8.86 -0.62 6.93e-15 Vitiligo; TGCT cis rs477895 1.000 rs1047206 chr11:64089216 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.19 0.42 8.41e-7 Mean platelet volume; TGCT cis rs9527 0.641 rs10786732 chr10:104762535 T/C cg15744005 chr10:104629667 AS3MT -0.44 -5.11 -0.42 1.18e-6 Arsenic metabolism; TGCT cis rs6570726 0.870 rs370653 chr6:145823642 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.680 rs11777459 chr8:58044241 A/T cg21724239 chr8:58056113 NA 0.34 4.44 0.37 1.97e-5 Developmental language disorder (linguistic errors); TGCT cis rs1670533 0.932 rs6599276 chr4:1056827 T/C cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs7647973 0.593 rs55997059 chr3:49858661 A/T cg03060546 chr3:49711283 APEH -0.66 -6.02 -0.48 1.86e-8 Menarche (age at onset); TGCT cis rs13326165 0.760 rs56357549 chr3:52374516 T/G cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs17401966 0.800 rs2039778 chr1:10354601 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.63 -0.38 9.17e-6 Hepatocellular carcinoma; TGCT cis rs7178572 1.000 rs12910361 chr15:77782335 A/G cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs9467773 0.967 rs6924865 chr6:26521353 A/G cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs4727027 0.933 rs4727028 chr7:148874666 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 -0.51 -4.76 -0.39 5.36e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1670533 1.000 rs10007978 chr4:1060984 A/T cg27284194 chr4:1044797 NA 0.7 6.04 0.48 1.63e-8 Recombination rate (females); TGCT cis rs3862260 0.509 rs10923879 chr1:120163831 A/G cg11530693 chr1:120165357 ZNF697 0.21 4.75 0.39 5.48e-6 Systemic lupus erythematosus; TGCT cis rs9486719 1.000 rs2472886 chr6:96864876 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs796364 0.806 rs11688194 chr2:200916239 C/T cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs12497850 0.931 rs7636057 chr3:48992582 C/T cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.98e-6 Parkinson's disease; TGCT cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg15659132 chr6:26577336 NA 0.85 10.29 0.68 2.45e-18 Intelligence (multi-trait analysis); TGCT cis rs9296092 0.560 rs7765393 chr6:33525598 A/T cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7772486 0.701 rs7772717 chr6:145954854 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.97 0.41 2.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7542091 0.635 rs7550733 chr1:210044968 G/A cg22029157 chr1:209979665 IRF6 0.64 6.12 0.48 1.12e-8 Monobrow; TGCT cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg23205692 chr1:25664452 TMEM50A 0.53 5.48 0.44 2.3e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs9906944 0.603 rs10853104 chr17:47092076 C/T cg07075026 chr17:47091521 IGF2BP1 -0.48 -5.23 -0.43 7e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7666738 0.546 rs7699578 chr4:98838893 T/C cg05340658 chr4:99064831 C4orf37 0.58 5.35 0.43 4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg01802117 chr1:53393560 SCP2 0.51 6.25 0.49 5.91e-9 Monocyte count; TGCT cis rs6901004 0.772 rs191632 chr6:111544882 C/T cg15721981 chr6:111408429 SLC16A10 -0.52 -4.55 -0.38 1.27e-5 Blood metabolite levels; TGCT cis rs733175 0.855 rs6853437 chr4:10005435 A/G cg11266682 chr4:10021025 SLC2A9 -0.47 -4.63 -0.38 9.05e-6 Psychosis and Alzheimer's disease; TGCT cis rs881375 0.967 rs1008381 chr9:123681116 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.43 0.44 2.89e-7 Rheumatoid arthritis; TGCT cis rs12210905 1.000 rs10946906 chr6:27252780 G/A cg08851530 chr6:28072375 NA 1.29 5.49 0.44 2.19e-7 Hip circumference adjusted for BMI; TGCT trans rs208520 0.690 rs1563929 chr6:66702108 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.26 0.71 1.09e-20 Exhaled nitric oxide output; TGCT cis rs77861329 1.000 rs123681 chr3:52209320 A/G cg08692210 chr3:52188851 WDR51A 0.94 4.83 0.4 3.91e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg05665937 chr4:1216051 CTBP1 0.24 4.65 0.39 8.32e-6 Obesity-related traits; TGCT cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg00814883 chr7:100076585 TSC22D4 -0.82 -8.23 -0.59 2.14e-13 Platelet count; TGCT cis rs7191700 0.712 rs7187741 chr16:11433103 C/G cg00044050 chr16:11439710 C16orf75 -0.88 -10.74 -0.69 2.04e-19 Multiple sclerosis; TGCT cis rs12681287 0.608 rs2953511 chr8:87340870 G/A cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs7584330 0.518 rs77789507 chr2:238440972 C/T cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs7904368 0.806 rs1130684 chr10:16859335 C/G cg14835575 chr10:16859367 RSU1 0.71 8.0 0.58 7.39e-13 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs9611565 0.592 rs28750375 chr22:41990644 A/C cg17554472 chr22:41940697 POLR3H -0.49 -5.15 -0.42 9.88e-7 Vitiligo; TGCT cis rs2524005 1.000 rs2524005 chr6:29899677 C/T cg27642588 chr6:29709602 LOC285830 0.41 5.47 0.44 2.42e-7 Bipolar disorder and schizophrenia; TGCT cis rs2836950 0.565 rs7279497 chr21:40531306 A/G cg17971929 chr21:40555470 PSMG1 0.52 4.69 0.39 6.98e-6 Menarche (age at onset); TGCT cis rs60871478 1.000 rs4720917 chr7:806998 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.6 0.38 1.04e-5 Cerebrospinal P-tau181p levels; TGCT cis rs9653442 0.545 rs2009094 chr2:100765077 G/A cg07810366 chr2:100720526 AFF3 -0.36 -5.31 -0.43 4.95e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs394563 0.619 rs4895787 chr6:149646500 G/A cg11245181 chr6:149772854 ZC3H12D 0.27 4.44 0.37 1.94e-5 Dupuytren's disease; TGCT cis rs9457247 0.765 rs4710171 chr6:167430186 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.57 -0.38 1.18e-5 Crohn's disease; TGCT cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg03609598 chr5:56110824 MAP3K1 -0.63 -4.96 -0.41 2.22e-6 Initial pursuit acceleration; TGCT cis rs7582180 0.606 rs4851299 chr2:100954191 C/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs1205863 1.000 rs1205881 chr6:11947313 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs10464366 0.544 rs34866559 chr7:39166071 G/A cg15212455 chr7:39170539 POU6F2 0.3 6.63 0.51 9.08e-10 IgG glycosylation; TGCT cis rs433598 0.514 rs75599714 chr16:20677754 T/C cg08248577 chr16:19727447 IQCK;C16orf88 -0.25 -4.82 -0.4 4.07e-6 Schizophrenia; TGCT cis rs2239547 0.522 rs2581797 chr3:52972468 C/T cg10802521 chr3:52805072 NEK4 0.65 6.14 0.48 1.02e-8 Schizophrenia; TGCT cis rs2710642 0.925 rs72807578 chr2:63008044 G/A cg17519650 chr2:63277830 OTX1 -0.59 -4.82 -0.4 4.13e-6 LDL cholesterol levels;LDL cholesterol; TGCT cis rs6087771 0.642 rs6060411 chr20:30222139 T/C cg10886678 chr20:30946050 ASXL1 -0.57 -4.5 -0.37 1.55e-5 Subcortical brain region volumes;Putamen volume; TGCT cis rs7208859 0.573 rs8078656 chr17:29080971 A/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9291683 0.566 rs13115776 chr4:10040189 C/G cg11266682 chr4:10021025 SLC2A9 0.61 7.73 0.57 3.25e-12 Bone mineral density; TGCT cis rs3806843 0.576 rs246021 chr5:140334504 C/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs12579753 0.957 rs35001833 chr12:82188510 C/G cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs7666738 0.830 rs7664051 chr4:98766970 C/G cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2832191 0.716 rs2692625 chr21:30446360 C/G cg08807101 chr21:30365312 RNF160 0.65 6.14 0.48 1.03e-8 Dental caries; TGCT cis rs17376456 0.569 rs7702348 chr5:93065683 A/G cg21475434 chr5:93447410 FAM172A -0.64 -5.2 -0.42 7.86e-7 Diabetic retinopathy; TGCT cis rs6663390 1.000 rs6663390 chr1:208092269 G/T cg03990033 chr1:208084030 CD34 0.49 4.98 0.41 2.05e-6 Facial morphology (factor 18); TGCT cis rs4919669 0.668 rs4146429 chr10:104401632 T/C cg05855489 chr10:104503620 C10orf26 0.76 4.44 0.37 1.98e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs8177253 1.000 rs8177261 chr3:133480588 A/C cg08439880 chr3:133502540 NA -0.31 -5.91 -0.47 3.08e-8 Iron status biomarkers; TGCT cis rs10946940 0.897 rs6456801 chr6:27625532 T/C cg10876282 chr6:28092338 ZSCAN16 0.48 4.83 0.4 4e-6 Systemic lupus erythematosus; TGCT cis rs77633900 0.614 rs280033 chr15:77023099 G/A cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs4727027 0.933 rs10277119 chr7:148849942 T/C cg23583168 chr7:148888333 NA -0.77 -10.1 -0.67 7.35e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg02953382 chr22:24373134 LOC391322 -0.76 -7.81 -0.57 2.09e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12477438 1.000 rs12053372 chr2:99810055 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.94 -8.59 -0.61 3.06e-14 Chronic sinus infection; TGCT cis rs4663866 1.000 rs4663867 chr2:239159964 G/C cg17283117 chr2:239148619 HES6 0.98 4.52 0.38 1.42e-5 Irritable bowel syndrome; TGCT cis rs9910055 0.762 rs2526021 chr17:42213347 G/A cg19774624 chr17:42201019 HDAC5 -0.83 -8.49 -0.61 5.19e-14 Total body bone mineral density; TGCT cis rs7698623 0.850 rs7684659 chr4:88769571 G/A cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs3785574 0.962 rs2727331 chr17:61926990 G/T cg01411255 chr17:61851458 DDX42;CCDC47 1.13 14.46 0.79 2.27e-28 Height; TGCT cis rs6540559 1.000 rs2235373 chr1:209963803 G/A cg22029157 chr1:209979665 IRF6 0.76 6.32 0.49 4.37e-9 Cleft lip with or without cleft palate; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg06753367 chr22:24256600 NA -0.25 -4.73 -0.39 5.98e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg13665807 chr20:60559372 TAF4 -0.44 -4.93 -0.4 2.59e-6 Body mass index; TGCT cis rs12579753 0.879 rs7958657 chr12:82135067 G/A cg21231944 chr12:82153410 PPFIA2 -0.36 -4.7 -0.39 6.72e-6 Resting heart rate; TGCT cis rs16957091 0.647 rs28810091 chr15:43156253 G/A cg17935677 chr15:44119062 WDR76 0.53 4.69 0.39 7.11e-6 MGMT methylation in smokers; TGCT cis rs6543140 0.601 rs78178597 chr2:103023596 G/T cg09003973 chr2:102972529 NA 0.76 6.19 0.49 8.22e-9 Blood protein levels; TGCT cis rs13108904 0.901 rs12509700 chr4:1296321 A/G cg00684032 chr4:1343700 KIAA1530 0.25 5.09 0.42 1.31e-6 Obesity-related traits; TGCT cis rs8051431 0.840 rs35484594 chr16:72021985 C/A cg06353428 chr16:71660113 MARVELD3 0.59 4.58 0.38 1.1e-5 LDL cholesterol levels; TGCT cis rs4478037 0.558 rs80167648 chr3:33069317 A/G cg19404215 chr3:33155277 CRTAP 1.03 4.92 0.4 2.66e-6 Major depressive disorder; TGCT cis rs1018836 0.923 rs4734266 chr8:91628147 C/T cg16814680 chr8:91681699 NA -0.86 -9.19 -0.64 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7772486 0.754 rs2064185 chr6:146066814 G/A cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13064411 0.696 rs6787026 chr3:113162117 A/G cg18753928 chr3:113234510 CCDC52 -0.66 -4.53 -0.38 1.39e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs11122272 0.735 rs910822 chr1:231498721 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.63 -0.51 9.1e-10 Hemoglobin concentration; TGCT cis rs4372836 0.504 rs13382966 chr2:29068882 T/C cg09522027 chr2:28974177 PPP1CB -0.6 -5.91 -0.47 3.15e-8 Body mass index; TGCT cis rs4780355 1.000 rs1111186 chr16:11347048 T/C cg00044050 chr16:11439710 C16orf75 0.55 4.78 0.39 4.93e-6 Crohn's disease and psoriasis; TGCT cis rs7772486 0.875 rs1412081 chr6:146409733 A/G cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs80282103 0.618 rs2387299 chr10:1163427 A/G cg18964960 chr10:1102726 WDR37 1.03 4.53 0.38 1.35e-5 Glomerular filtration rate (creatinine); TGCT cis rs7043114 0.507 rs10820971 chr9:95161740 G/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.6 -0.45 1.32e-7 Height; TGCT cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs739496 0.843 rs616559 chr12:112003350 C/T cg10833066 chr12:111807467 FAM109A -0.34 -4.95 -0.41 2.4e-6 Platelet count; TGCT cis rs7945705 0.967 rs10769968 chr11:8907583 G/C cg21881798 chr11:8931708 C11orf17;ST5 0.42 4.7 0.39 6.86e-6 Hemoglobin concentration; TGCT cis rs950169 0.887 rs3860265 chr15:84945185 C/T cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs9788721 0.836 rs2009746 chr15:78754102 A/G cg18825076 chr15:78729989 IREB2 -0.32 -5.02 -0.41 1.76e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs826838 1.000 rs9795768 chr12:39012479 T/C cg13010199 chr12:38710504 ALG10B 0.83 6.91 0.53 2.21e-10 Heart rate; TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs1964356 0.524 rs7839585 chr8:8854235 C/G cg15556689 chr8:8085844 FLJ10661 -0.57 -4.69 -0.39 7.16e-6 Mean corpuscular volume; TGCT cis rs62380364 0.602 rs650702 chr5:88055313 G/A cg24804195 chr5:87968844 LOC645323 -0.57 -5.56 -0.45 1.59e-7 Intelligence (multi-trait analysis); TGCT cis rs9858542 0.953 rs9837027 chr3:49597013 C/T cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6456156 0.766 rs150112 chr6:167509878 C/T cg07741184 chr6:167504864 NA -0.24 -4.74 -0.39 5.7e-6 Primary biliary cholangitis; TGCT cis rs28595532 0.920 rs114639588 chr4:119736176 T/C cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs17767294 0.708 rs72847383 chr6:27875641 G/A cg08851530 chr6:28072375 NA 1.57 7.27 0.55 3.59e-11 Parkinson's disease; TGCT cis rs7432375 0.580 rs4678442 chr3:136532971 A/G cg15507776 chr3:136538369 TMEM22 0.55 5.63 0.45 1.15e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7809950 0.906 rs2253269 chr7:107201114 C/T cg23024343 chr7:107201750 COG5 -0.34 -5.26 -0.43 6.08e-7 Coronary artery disease; TGCT cis rs2066819 1.000 rs79436528 chr12:56686997 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs67073037 0.955 rs56289239 chr2:29137309 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs6683273 0.830 rs57342206 chr1:3227501 C/T cg17435683 chr1:3230609 PRDM16 -0.4 -4.53 -0.38 1.35e-5 QRS duration; TGCT cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs981844 0.767 rs6857738 chr4:154689140 A/C cg14289246 chr4:154710475 SFRP2 -0.91 -8.31 -0.6 1.38e-13 Response to statins (LDL cholesterol change); TGCT trans rs7613875 0.620 rs7430334 chr3:50078221 T/C cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT cis rs12049351 0.774 rs16849844 chr1:229620396 A/G cg12130225 chr1:229698885 NA -0.41 -4.79 -0.4 4.64e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs587847 0.737 rs28440992 chr15:37625116 A/G cg00216138 chr15:37171175 LOC145845 0.31 4.57 0.38 1.15e-5 Intraocular pressure; TGCT cis rs4077515 0.967 rs4567159 chr9:139277059 G/A cg13741927 chr9:139327495 INPP5E -0.2 -4.59 -0.38 1.06e-5 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs4900538 0.819 rs72700604 chr14:102882307 G/A cg18135206 chr14:102964638 TECPR2 -0.2 -4.53 -0.38 1.39e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs10464366 0.912 rs2030960 chr7:39106010 G/A cg18850127 chr7:39170497 POU6F2 0.21 4.5 0.37 1.55e-5 IgG glycosylation; TGCT cis rs2034088 0.833 rs4968120 chr17:431364 T/G cg06217071 chr17:408420 NA 0.36 5.35 0.43 4.18e-7 Hip circumference adjusted for BMI; TGCT cis rs17076896 0.786 rs7335968 chr13:19937189 C/A cg00777926 chr13:20807375 GJB6 -0.41 -4.82 -0.4 4.03e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs3125734 0.633 rs4979773 chr10:63967731 G/C cg09941381 chr10:64027924 RTKN2 -0.37 -5.7 -0.46 8.15e-8 Rheumatoid arthritis; TGCT cis rs1451375 0.794 rs11238133 chr7:50542914 A/C cg18232548 chr7:50535776 DDC -0.44 -6.52 -0.51 1.59e-9 Malaria; TGCT cis rs10791097 0.694 rs10894273 chr11:130742155 G/T cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs4262150 0.544 rs55802718 chr5:151916541 G/A cg26032021 chr14:54804413 NA 0.39 6.64 0.51 8.72e-10 Bipolar disorder and schizophrenia; TGCT cis rs903263 0.601 rs12405120 chr1:84556523 C/T cg09664975 chr1:84543551 PRKACB -0.49 -4.73 -0.39 6.05e-6 Breast cancer (male); TGCT cis rs790110 1.000 rs790110 chr3:122384020 T/G cg07366462 chr3:123162899 ADCY5 0.42 4.71 0.39 6.54e-6 Acoustic startle blink response; TGCT cis rs9952991 0.941 rs2542151 chr18:12779947 G/T cg23598886 chr18:12777645 NA 0.62 5.9 0.47 3.26e-8 Inflammatory skin disease; TGCT trans rs1814175 0.715 rs1722007 chr11:49897319 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.63e-13 Height; TGCT cis rs9322193 0.923 rs7767622 chr6:150002902 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2742417 1.000 rs2673039 chr3:45748435 A/G cg04837898 chr3:45731254 SACM1L -0.51 -5.23 -0.42 7.13e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg27211696 chr2:191398769 TMEM194B 0.29 5.3 0.43 5.19e-7 Pulse pressure; TGCT cis rs709400 0.691 rs12888077 chr14:103872553 G/T cg12935359 chr14:103987150 CKB 0.34 5.22 0.42 7.18e-7 Body mass index; TGCT cis rs7714584 1.000 rs3900064 chr5:150264414 C/G cg22134413 chr5:150180641 NA -0.85 -6.15 -0.48 9.74e-9 Crohn's disease; TGCT cis rs2046867 0.818 rs60228315 chr3:72805034 C/A cg25664220 chr3:72788482 NA -0.57 -7.05 -0.53 1.13e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs40363 0.645 rs250631 chr16:3523215 G/C cg22508957 chr16:3507546 NAT15 0.5 5.75 0.46 6.64e-8 Tuberculosis; TGCT cis rs2463822 0.583 rs7104825 chr11:62026833 C/T cg06239285 chr11:62104954 ASRGL1 -0.96 -6.11 -0.48 1.17e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2197308 0.692 rs1904964 chr12:37933241 T/A cg13010199 chr12:38710504 ALG10B 0.63 5.04 0.41 1.58e-6 Morning vs. evening chronotype; TGCT cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.82 7.61 0.56 5.98e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs739496 0.546 rs12426493 chr12:112344756 T/C cg10833066 chr12:111807467 FAM109A 0.39 5.65 0.45 1.03e-7 Platelet count; TGCT cis rs7833790 0.777 rs7815272 chr8:82691809 T/G cg17211192 chr8:82754475 SNX16 -1.04 -8.46 -0.6 6.42e-14 Diastolic blood pressure; TGCT cis rs116161686 0.500 rs76610459 chr1:210050756 T/G cg22029157 chr1:209979665 IRF6 0.74 5.6 0.45 1.31e-7 Coronary artery disease; TGCT cis rs7568458 0.870 rs6719046 chr2:85757371 G/A cg17127132 chr2:85788382 GGCX 0.72 6.69 0.51 6.94e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs28386778 0.704 rs1051688 chr17:62006433 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.86 -10.09 -0.67 7.49e-18 Prudent dietary pattern; TGCT cis rs7639513 0.520 rs79141906 chr3:12711977 A/C cg23032965 chr3:12705835 RAF1 0.75 7.85 0.58 1.69e-12 Itch intensity from mosquito bite; TGCT cis rs4237845 0.844 rs4630335 chr12:58302258 A/G cg23860436 chr12:58378763 NA 0.33 4.9 0.4 2.92e-6 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.559 rs10815172 chr9:5212254 T/A cg02405213 chr9:5042618 JAK2 -0.67 -8.3 -0.6 1.49e-13 Pediatric autoimmune diseases; TGCT cis rs28595532 0.920 rs114462478 chr4:119752656 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9467773 1.000 rs4871 chr6:26545632 G/A cg26531700 chr6:26746687 NA 0.46 4.46 0.37 1.82e-5 Intelligence (multi-trait analysis); TGCT cis rs3858526 0.959 rs11039699 chr11:5951091 G/A cg13902645 chr11:5959945 NA -0.48 -5.0 -0.41 1.95e-6 DNA methylation (variation); TGCT cis rs1008375 1.000 rs2159583 chr4:17658838 T/C cg16339924 chr4:17578868 LAP3 0.63 5.37 0.43 3.77e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1344694 0.566 rs13029765 chr2:216894976 A/T cg12620499 chr2:216877984 MREG 0.82 9.34 0.64 4.98e-16 Alcohol dependence; TGCT cis rs7592578 0.766 rs35818159 chr2:191409616 C/G cg11845111 chr2:191398756 TMEM194B -0.42 -4.48 -0.37 1.69e-5 Diastolic blood pressure; TGCT cis rs736408 0.812 rs2270197 chr3:52824095 T/G cg07507251 chr3:52567010 NT5DC2 0.42 5.8 0.46 5.29e-8 Bipolar disorder; TGCT cis rs10992471 0.603 rs987553 chr9:95298694 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.68 -0.45 9.01e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4234284 0.556 rs7650549 chr3:126968288 C/T cg25436886 chr3:127056972 NA -0.5 -4.9 -0.4 2.91e-6 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs7267979 1.000 rs2482911 chr20:25395528 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10461617 0.512 rs7715746 chr5:56048837 C/T cg24531977 chr5:56204891 C5orf35 -0.46 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs6543140 0.964 rs4851578 chr2:103028951 T/G cg09003973 chr2:102972529 NA 0.58 4.83 0.4 3.87e-6 Blood protein levels; TGCT cis rs4268898 0.722 rs11691212 chr2:24404733 A/G cg02683114 chr2:24398427 C2orf84 0.19 4.76 0.39 5.37e-6 Asthma; TGCT cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs881375 0.678 rs9886724 chr9:123665019 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.92e-7 Rheumatoid arthritis; TGCT cis rs6582630 0.502 rs11181230 chr12:38300085 A/G cg13010199 chr12:38710504 ALG10B 0.57 4.45 0.37 1.89e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs12410462 0.502 rs75429875 chr1:227957200 A/C cg23173402 chr1:227635558 NA 0.7 4.81 0.4 4.31e-6 Major depressive disorder; TGCT cis rs9467773 1.000 rs6922824 chr6:26553815 C/G cg26531700 chr6:26746687 NA -0.47 -4.55 -0.38 1.25e-5 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs4815405 chr20:25317492 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2067615 0.579 rs7975576 chr12:107132501 A/G cg15890332 chr12:107067104 RFX4 0.29 5.84 0.46 4.33e-8 Heart rate; TGCT cis rs10791097 0.694 rs4459316 chr11:130756176 T/C cg14779329 chr11:130786720 SNX19 0.29 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2663905 0.706 rs7162859 chr15:81360038 C/T cg18028999 chr15:81426610 C15orf26 0.73 6.54 0.51 1.44e-9 QT interval (drug interaction); TGCT cis rs9486719 1.000 rs4343922 chr6:96876903 C/T cg18709589 chr6:96969512 KIAA0776 0.67 5.23 0.43 7e-7 Migraine;Coronary artery disease; TGCT cis rs1150668 0.799 rs2142730 chr6:28266149 T/C cg11262757 chr6:27280423 POM121L2 0.46 4.62 0.38 9.52e-6 Pubertal anthropometrics; TGCT cis rs7226408 1.000 rs72883555 chr18:34364093 G/A cg06757138 chr18:34340585 FHOD3 0.28 4.76 0.39 5.23e-6 Obesity-related traits; TGCT cis rs4321325 1.000 rs4321325 chr2:127950997 C/T cg09760422 chr2:128146352 NA 0.39 4.88 0.4 3.23e-6 Protein C levels; TGCT cis rs4727027 0.899 rs11768971 chr7:148825826 C/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs17685 0.753 rs1637045 chr7:75703895 T/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.57 0.61 3.45e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs4862750 0.872 rs10027252 chr4:187873462 T/G cg10295955 chr4:187884368 NA -0.93 -12.59 -0.75 6.43e-24 Lobe attachment (rater-scored or self-reported); TGCT cis rs60871478 0.588 rs56205589 chr7:910419 G/A cg15782153 chr7:917662 C7orf20 0.57 5.12 0.42 1.14e-6 Cerebrospinal P-tau181p levels; TGCT trans rs208520 0.690 rs2126120 chr6:66742754 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs9527 0.545 rs7095304 chr10:104954795 G/A cg15744005 chr10:104629667 AS3MT -0.41 -4.78 -0.39 4.88e-6 Arsenic metabolism; TGCT cis rs7666738 0.791 rs34437628 chr4:99029232 C/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9372498 0.505 rs56406560 chr6:118991787 G/A cg07617317 chr6:118971624 C6orf204 0.45 4.83 0.4 3.93e-6 Diastolic blood pressure; TGCT cis rs9291683 0.655 rs3822242 chr4:10094904 T/C cg11266682 chr4:10021025 SLC2A9 -0.51 -6.15 -0.48 9.58e-9 Bone mineral density; TGCT cis rs4862750 0.872 rs10027252 chr4:187873462 T/G cg11301795 chr4:187892539 NA -0.34 -5.0 -0.41 1.94e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7914558 1.000 rs12255047 chr10:104760752 G/A cg04362960 chr10:104952993 NT5C2 0.6 5.42 0.44 2.99e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6089829 0.962 rs6089825 chr20:61668447 C/T cg03213289 chr20:61660250 NA 0.7 10.08 0.67 8.18e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs10782582 0.593 rs17585530 chr1:76134990 G/A cg10523679 chr1:76189770 ACADM -0.68 -7.1 -0.54 8.65e-11 Daytime sleep phenotypes; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg08859206 chr1:53392774 SCP2 -0.44 -6.62 -0.51 9.74e-10 Monocyte count; TGCT cis rs478304 0.593 rs4645933 chr11:65485120 C/T cg27068330 chr11:65405492 SIPA1 -1.07 -7.79 -0.57 2.29e-12 Acne (severe); TGCT cis rs7666738 0.611 rs34982650 chr4:98819530 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.25 0.43 6.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13102973 0.933 rs7656595 chr4:135875693 G/A cg14419869 chr4:135874104 NA 0.24 4.46 0.37 1.83e-5 Subjective well-being; TGCT cis rs6121246 0.567 rs6060344 chr20:30207316 A/G cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs7727544 0.582 rs3805683 chr5:131535125 T/G cg14196790 chr5:131705035 SLC22A5 0.33 4.49 0.37 1.59e-5 Blood metabolite levels; TGCT cis rs2549003 0.966 rs10065633 chr5:131816716 T/C cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs2836633 0.929 rs764482 chr21:40033661 C/G cg05519781 chr21:40033154 ERG 0.69 6.57 0.51 1.27e-9 Coronary artery disease; TGCT trans rs4332037 1.000 rs4332037 chr7:1950809 C/T cg10840412 chr1:235813424 GNG4 1.06 8.34 0.6 1.21e-13 Bipolar disorder; TGCT cis rs2640806 0.505 rs7818838 chr8:97359279 A/C cg04026948 chr8:97953330 PGCP -0.26 -4.64 -0.38 8.63e-6 Obesity-related traits; TGCT cis rs713587 0.713 rs11682135 chr2:25205377 G/A cg01884057 chr2:25150051 NA -0.38 -7.81 -0.57 2.04e-12 Body mass index in non-asthmatics; TGCT cis rs2072499 1.000 rs2072499 chr1:156169610 A/G cg06970220 chr1:156163860 SLC25A44 0.67 5.9 0.47 3.22e-8 Testicular germ cell tumor; TGCT cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs478304 0.651 rs78412025 chr11:65495696 T/C cg10518572 chr11:65560635 OVOL1 -0.24 -4.67 -0.39 7.83e-6 Acne (severe); TGCT cis rs79349575 0.783 rs318095 chr17:46974734 T/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.06e-8 Type 2 diabetes; TGCT cis rs9486719 1.000 rs2064947 chr6:97052754 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs1843834 0.517 rs1908252 chr2:225484736 G/A cg22455342 chr2:225449267 CUL3 0.62 5.63 0.45 1.12e-7 IgE levels in asthmatics (D.p. specific); TGCT cis rs9549260 0.664 rs9532575 chr13:41225361 G/C cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs617219 0.710 rs10054122 chr5:78581371 A/T cg05890484 chr5:78407552 BHMT -0.36 -4.88 -0.4 3.25e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7216064 0.953 rs4791046 chr17:65851973 G/A cg12091567 chr17:66097778 LOC651250 -0.89 -7.11 -0.54 8.05e-11 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs3771570 0.901 rs73006381 chr2:242406654 G/C cg21155796 chr2:242212141 HDLBP 0.93 6.69 0.52 6.74e-10 Prostate cancer; TGCT cis rs2180341 0.521 rs12203812 chr6:127617816 A/T cg27446573 chr6:127587934 RNF146 0.64 5.66 0.45 1.01e-7 Breast cancer; TGCT cis rs12579753 0.719 rs10862377 chr12:82270172 C/T cg07988820 chr12:82153109 PPFIA2 -0.42 -4.44 -0.37 1.97e-5 Resting heart rate; TGCT cis rs1670533 1.000 rs651017 chr4:1091062 A/G cg20887711 chr4:1340912 KIAA1530 0.6 4.53 0.38 1.38e-5 Recombination rate (females); TGCT cis rs5758659 0.714 rs5758578 chr22:42490292 A/C cg15557168 chr22:42548783 NA 0.18 4.56 0.38 1.23e-5 Cognitive function; TGCT cis rs2204008 0.624 rs2320449 chr12:38224190 T/C cg13010199 chr12:38710504 ALG10B 0.63 4.98 0.41 2.09e-6 Bladder cancer; TGCT cis rs7833790 0.724 rs10958045 chr8:82722994 T/C cg27398817 chr8:82754497 SNX16 -0.67 -5.34 -0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs7772486 0.790 rs6570724 chr6:146151283 T/C cg23711669 chr6:146136114 FBXO30 0.89 10.12 0.67 6.38e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs8013055 0.846 rs7160747 chr14:105983740 A/G cg23356831 chr14:105996513 TMEM121 0.33 4.83 0.4 3.86e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg18538332 chr22:24372958 LOC391322 -0.99 -12.8 -0.75 2e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs968451 0.865 rs5757609 chr22:39707845 G/C cg17798944 chr22:39715225 SNORD43;RPL3 0.83 8.1 0.59 4.48e-13 Primary biliary cholangitis; TGCT cis rs7666738 0.830 rs28795113 chr4:98951331 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg02953382 chr22:24373134 LOC391322 0.78 6.56 0.51 1.33e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs478304 0.654 rs7115734 chr11:65458964 G/A cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.79e-13 Acne (severe); TGCT cis rs6860806 0.507 rs270615 chr5:131641573 G/C cg24060327 chr5:131705240 SLC22A5 -0.73 -7.82 -0.57 1.94e-12 Breast cancer; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg09033563 chr22:24373618 LOC391322 -0.47 -4.52 -0.38 1.41e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -8.31 -0.6 1.43e-13 Platelet count; TGCT cis rs7666738 0.830 rs13124127 chr4:98990729 G/A cg18180107 chr4:99064573 C4orf37 0.51 4.68 0.39 7.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 0.862 rs10263690 chr7:65766453 G/C cg11764359 chr7:65958608 NA -0.55 -5.0 -0.41 1.94e-6 Aortic root size; TGCT cis rs1580019 0.563 rs13225132 chr7:32800975 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.83 0.4 3.88e-6 Cognitive ability; TGCT cis rs13242816 1.000 rs34424131 chr7:116119002 G/A cg16553024 chr7:116138462 CAV2 -0.45 -4.81 -0.4 4.32e-6 P wave duration; TGCT cis rs6461049 0.800 rs3778977 chr7:2159746 C/T cg22963979 chr7:1858916 MAD1L1 -0.41 -6.71 -0.52 6.13e-10 Schizophrenia; TGCT cis rs28595532 0.920 rs116108618 chr4:119763585 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs1865760 0.516 rs9379819 chr6:26049819 A/C cg16482183 chr6:26056742 HIST1H1C 0.57 5.0 0.41 1.93e-6 Height; TGCT cis rs3735485 0.638 rs10236356 chr7:45138465 C/T cg16731821 chr7:44153333 AEBP1 -0.25 -4.66 -0.39 8.17e-6 Granulocyte count;White blood cell count;Neutrophil count;Sum basophil neutrophil counts;Myeloid white cell count;Sum neutrophil eosinophil counts;Monocyte percentage of white cells;Lymphocyte counts;Granulocyte percentage of myeloid white cells; TGCT cis rs9381040 0.610 rs717883 chr6:41045270 T/C cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT trans rs208520 0.690 rs1885100 chr6:66871047 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs7169223 0.653 rs12905740 chr15:79082364 C/T cg03762349 chr15:79060523 ADAMTS7 0.24 4.96 0.41 2.24e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs9611519 0.780 rs2284079 chr22:41658632 C/T cg03806693 chr22:41940476 POLR3H -0.74 -7.15 -0.54 6.65e-11 Neuroticism; TGCT cis rs62380364 0.602 rs591228 chr5:88064809 G/A cg22951263 chr5:87985283 NA -0.58 -6.28 -0.49 5.32e-9 Intelligence (multi-trait analysis); TGCT cis rs875971 0.660 rs10281080 chr7:66042441 T/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs8013055 0.846 rs10139300 chr14:105974501 A/G cg19700328 chr14:106028568 NA -0.53 -5.91 -0.47 3.03e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs12142240 0.698 rs56358525 chr1:46849520 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs941408 0.515 rs1640262 chr19:2779134 C/T cg06609049 chr19:2785107 THOP1 -1.09 -12.69 -0.75 3.58e-24 Total cholesterol levels; TGCT cis rs854765 0.583 rs4925125 chr17:17794444 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.72 -7.63 -0.57 5.43e-12 Total body bone mineral density; TGCT cis rs4478858 0.647 rs6425720 chr1:31709555 A/G cg00250761 chr1:31883323 NA -0.27 -4.9 -0.4 2.89e-6 Alcohol dependence; TGCT cis rs9814567 0.752 rs6779326 chr3:134330027 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs700651 0.789 rs62277902 chr2:198879443 T/A cg00792783 chr2:198669748 PLCL1 -0.59 -5.27 -0.43 5.92e-7 Intracranial aneurysm; TGCT cis rs11148252 0.595 rs4885325 chr13:53171317 C/T cg00495681 chr13:53174319 NA 0.62 6.15 0.48 1e-8 Lewy body disease; TGCT cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg06238570 chr21:40685208 BRWD1 0.67 6.41 0.5 2.8e-9 Cognitive function; TGCT cis rs9807989 0.507 rs4851577 chr2:103028921 T/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.18e-7 Asthma; TGCT cis rs9640161 0.830 rs6722 chr7:150068933 T/C cg21361702 chr7:150065534 REPIN1 0.49 4.56 0.38 1.19e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2180341 0.960 rs9398842 chr6:127674662 T/C cg27446573 chr6:127587934 RNF146 1.14 10.91 0.7 7.51e-20 Breast cancer; TGCT cis rs10791323 0.569 rs1119852 chr11:133743022 C/A cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs4455778 0.580 rs4551289 chr7:49112437 G/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs6121246 0.559 rs6058462 chr20:30367674 C/T cg13852791 chr20:30311386 BCL2L1 0.83 8.16 0.59 3.22e-13 Mean corpuscular hemoglobin; TGCT cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg16145915 chr7:1198662 ZFAND2A -0.46 -5.47 -0.44 2.36e-7 Longevity;Endometriosis; TGCT cis rs1348850 0.915 rs10930798 chr2:178446141 G/A cg22681709 chr2:178499509 PDE11A -0.36 -4.47 -0.37 1.75e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7428 0.847 rs1969260 chr2:85568810 C/T cg24342717 chr2:85555507 TGOLN2 -0.4 -6.42 -0.5 2.6e-9 Ear protrusion; TGCT cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs4773330 0.660 rs1557247 chr13:111807648 C/T cg14154082 chr13:112174009 NA 0.4 4.46 0.37 1.83e-5 Bilirubin levels; TGCT cis rs12510870 0.599 rs10028196 chr4:74389073 A/T cg05868023 chr4:75230803 EREG 0.55 4.7 0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs5750830 0.649 rs4821894 chr22:39809820 G/C cg05872129 chr22:39784769 NA -1.01 -11.09 -0.71 2.82e-20 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.790 rs1832362 chr6:146179955 C/T cg23711669 chr6:146136114 FBXO30 0.92 10.44 0.68 1.06e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.552 rs10896384 chr11:68720011 A/G cg06028808 chr11:68637592 NA -0.51 -6.59 -0.51 1.1e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs597539 0.690 rs635529 chr11:68626294 C/T cg21862992 chr11:68658383 NA 0.48 6.47 0.5 2.03e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs564309 0.681 rs4581279 chr1:228622347 A/G cg22700015 chr1:228743131 NA -0.74 -4.46 -0.37 1.78e-5 Hip circumference (psychosocial stress interaction); TGCT cis rs4372836 0.504 rs10177006 chr2:29088256 A/G cg09522027 chr2:28974177 PPP1CB -0.57 -5.63 -0.45 1.14e-7 Body mass index; TGCT cis rs4253772 0.530 rs6008662 chr22:46713917 G/A cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.73 5.34 0.43 4.21e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs7786808 0.741 rs62479982 chr7:158227546 A/G cg01191920 chr7:158217561 PTPRN2 -0.44 -6.66 -0.51 7.85e-10 Obesity-related traits; TGCT cis rs765787 0.530 rs4774542 chr15:45526026 A/C cg24006582 chr15:45444508 DUOX1 0.26 5.75 0.46 6.64e-8 Uric acid levels; TGCT cis rs909002 0.849 rs6425777 chr1:32105447 G/C cg11573219 chr1:32083031 HCRTR1 -0.47 -6.09 -0.48 1.29e-8 Intelligence (multi-trait analysis); TGCT cis rs6586111 0.935 rs4933463 chr10:82372866 A/C cg03086067 chr10:82368399 SH2D4B -0.24 -4.7 -0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs9467773 0.967 rs9461267 chr6:26525455 T/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs7818688 0.674 rs74632106 chr8:95978032 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs524023 1.000 rs559946 chr11:64358605 T/C cg07733098 chr11:64478343 NRXN2 -0.31 -4.67 -0.39 7.59e-6 Urate levels in obese individuals; TGCT cis rs7267979 1.000 rs6107047 chr20:25442097 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7208859 0.623 rs56812022 chr17:29068733 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs12599106 0.792 rs11648801 chr16:34360980 C/T cg01516881 chr6:292596 DUSP22 -0.64 -6.72 -0.52 5.81e-10 Menopause (age at onset); TGCT cis rs7089973 0.872 rs34064819 chr10:116621154 C/A cg03647239 chr10:116582469 FAM160B1 0.53 4.73 0.39 6.08e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs10992471 0.513 rs710163 chr9:95059804 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.54 4.98 0.41 2.06e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs13191362 0.688 rs73025321 chr6:162974896 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.63 4.68 0.39 7.32e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs916888 0.647 rs199449 chr17:44808902 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.64 4.91 0.4 2.82e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3796352 0.568 rs11713376 chr3:52958927 A/G cg15956490 chr3:53032818 SFMBT1 0.42 4.53 0.38 1.39e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 4.98 0.41 2.08e-6 Prudent dietary pattern; TGCT cis rs473651 0.935 rs474478 chr2:239335473 C/T cg18131467 chr2:239335373 ASB1 1.01 14.5 0.79 1.78e-28 Multiple system atrophy; TGCT cis rs12110303 1 rs12110303 chr5:90662839 G/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.98 8.99 0.63 3.39e-15 Breast cancer; TGCT cis rs2836950 0.840 rs12482317 chr21:40588241 A/G cg06238570 chr21:40685208 BRWD1 -0.56 -5.63 -0.45 1.16e-7 Menarche (age at onset); TGCT cis rs3806843 0.966 rs1030163 chr5:140185132 G/A cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT trans rs6089829 0.962 rs11086151 chr20:61664644 C/T cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT trans rs72809171 0.661 rs57817267 chr17:12493228 T/C cg03074370 chr19:50352995 PTOV1 0.51 6.93 0.53 1.99e-10 Male-pattern baldness; TGCT cis rs10057188 0.786 rs28437030 chr5:77868354 T/C cg06873401 chr5:77792105 LHFPL2 -0.23 -4.58 -0.38 1.14e-5 Pulse pressure; TGCT cis rs12908161 1.000 rs62021219 chr15:85256159 C/T cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs8141529 0.719 rs132561 chr22:29351179 C/T cg02153584 chr22:29168773 CCDC117 -0.65 -4.76 -0.39 5.31e-6 Lymphocyte counts; TGCT cis rs7727544 0.618 rs2631367 chr5:131705458 C/G cg14196790 chr5:131705035 SLC22A5 -0.38 -5.23 -0.43 6.89e-7 Blood metabolite levels; TGCT cis rs3806843 0.576 rs550475 chr5:140273528 G/C cg07102913 chr5:140593443 PCDHB13 -0.47 -4.52 -0.38 1.42e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs769267 0.896 rs11882123 chr19:19386339 A/G cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg03351412 chr1:154909251 PMVK 0.51 4.73 0.39 5.9e-6 Prostate cancer; TGCT cis rs9303401 0.659 rs12948133 chr17:56673602 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs7584330 0.554 rs3751109 chr2:238427194 T/C cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs4727027 0.801 rs12666337 chr7:148796253 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.68 0.39 7.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs35146811 0.625 rs858514 chr7:99825748 A/G cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs6840360 1.000 rs6840678 chr4:152604331 C/G cg17479576 chr4:152424074 FAM160A1 0.55 5.87 0.47 3.79e-8 Intelligence (multi-trait analysis); TGCT cis rs2594989 1.000 rs2606752 chr3:11360170 A/G cg00170343 chr3:11313890 ATG7 0.66 4.83 0.4 3.92e-6 Circulating chemerin levels; TGCT cis rs4865875 0.681 rs4242044 chr5:54097130 A/G cg03861379 chr5:54128677 NA -0.56 -5.04 -0.41 1.62e-6 Sense of smell; TGCT cis rs7523273 0.526 rs677715 chr1:208047284 A/G cg22525895 chr1:207977042 MIR29B2 0.32 5.12 0.42 1.14e-6 Schizophrenia; TGCT cis rs6141769 0.542 rs6087976 chr20:31316287 G/A cg13636640 chr20:31349939 DNMT3B -0.52 -4.54 -0.38 1.34e-5 Subjective well-being; TGCT cis rs2361718 0.564 rs2304844 chr17:78084507 G/C cg21238619 chr17:78079768 GAA -0.34 -4.52 -0.38 1.44e-5 Yeast infection; TGCT cis rs7829975 0.626 rs907183 chr8:8729761 C/G cg06636001 chr8:8085503 FLJ10661 -0.73 -7.01 -0.53 1.37e-10 Mood instability; TGCT cis rs765787 0.530 rs4514617 chr15:45535439 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.55 -0.45 1.67e-7 Uric acid levels; TGCT cis rs36051895 0.659 rs59668095 chr9:5043688 C/G cg02405213 chr9:5042618 JAK2 -0.72 -9.64 -0.65 9.46e-17 Pediatric autoimmune diseases; TGCT cis rs7572733 0.534 rs696817 chr2:198722225 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs11785400 0.762 rs9694556 chr8:143727841 A/G cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs6831352 0.840 rs35073321 chr4:100053276 G/A cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs4819052 0.807 rs7283915 chr21:46671288 T/C cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs910187 0.605 rs8124918 chr20:45811860 A/G cg27589058 chr20:45804311 EYA2 -0.36 -7.81 -0.57 2.11e-12 Migraine; TGCT cis rs4722166 0.630 rs6461667 chr7:22796743 A/G cg13104385 chr7:22767384 IL6 0.22 5.03 0.41 1.65e-6 Lung cancer; TGCT cis rs4845570 0.764 rs12141652 chr1:151716711 A/T cg07092448 chr1:151763213 TDRKH -1.03 -7.53 -0.56 8.99e-12 Coronary artery disease; TGCT cis rs1008375 0.966 rs3775927 chr4:17599894 G/T cg18681998 chr4:17616180 MED28 0.92 9.41 0.65 3.31e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7582180 0.629 rs2309796 chr2:100954385 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.95 -0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs34035316 chr21:40594023 T/C cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.3e-9 Cognitive function; TGCT trans rs7618501 0.602 rs2526754 chr3:50125996 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.5 -0.65 2.02e-16 Intelligence (multi-trait analysis); TGCT cis rs9733 0.596 rs6587516 chr1:150623221 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs453301 0.682 rs2929451 chr8:9085295 A/T cg06636001 chr8:8085503 FLJ10661 0.66 6.04 0.48 1.65e-8 Joint mobility (Beighton score); TGCT cis rs3008870 1.000 rs11208979 chr1:67442275 C/T cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs6598955 0.671 rs11247884 chr1:26577338 C/T cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs67311347 1.000 rs17078813 chr3:40434162 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs3862260 0.509 rs3795663 chr1:120165187 G/A cg11530693 chr1:120165357 ZNF697 0.21 4.75 0.39 5.48e-6 Systemic lupus erythematosus; TGCT cis rs6964587 0.610 rs7788951 chr7:91468765 A/T cg17063962 chr7:91808500 NA 0.73 6.7 0.52 6.48e-10 Breast cancer; TGCT cis rs6964587 1.000 rs55745934 chr7:91670998 T/C cg22709100 chr7:91322751 NA 0.27 4.46 0.37 1.84e-5 Breast cancer; TGCT cis rs9913156 0.841 rs34230287 chr17:4613630 C/T cg19197139 chr17:4613644 ARRB2 0.86 7.84 0.58 1.73e-12 Lymphocyte counts; TGCT cis rs2201728 0.902 rs12498658 chr4:100237821 G/A cg07219303 chr4:100140905 ADH6 -0.36 -5.42 -0.44 2.98e-7 Cardiac Troponin-T levels; TGCT cis rs344364 0.511 rs1657144 chr16:1963989 C/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.48 -5.26 -0.43 6.1e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7647973 0.961 rs11130187 chr3:49307872 T/C cg07690219 chr3:49449608 TCTA;RHOA -0.55 -4.48 -0.37 1.68e-5 Menarche (age at onset); TGCT cis rs7568458 0.684 rs1048739 chr2:85764968 T/G cg17127132 chr2:85788382 GGCX 0.52 4.63 0.38 9.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3820068 0.581 rs61056912 chr1:15926296 A/G cg05660106 chr1:15850417 CASP9 0.74 7.27 0.55 3.53e-11 Systolic blood pressure; TGCT cis rs3540 0.512 rs3862433 chr15:91076028 G/A cg22089800 chr15:90895588 ZNF774 -0.76 -7.91 -0.58 1.22e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs8031584 0.781 rs4779498 chr15:31177476 C/T cg08704250 chr15:31115839 NA -0.46 -6.73 -0.52 5.7e-10 Huntington's disease progression; TGCT cis rs12477438 0.520 rs13010904 chr2:99754289 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 17.85 0.85 4.6e-36 Chronic sinus infection; TGCT cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg03452623 chr4:187889614 NA -0.35 -5.28 -0.43 5.49e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1801251 0.963 rs6739638 chr2:233576015 G/A cg08000102 chr2:233561755 GIGYF2 0.66 6.8 0.52 3.88e-10 Coronary artery disease; TGCT cis rs7027203 0.828 rs4344139 chr9:96600298 T/C cg14598338 chr9:96623480 NA -0.61 -9.54 -0.65 1.68e-16 DNA methylation (variation); TGCT cis rs7584330 0.554 rs9646716 chr2:238443784 C/T cg08992911 chr2:238395768 MLPH 0.64 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs8037137 0.915 rs8026714 chr15:91522253 G/A cg22570213 chr15:91497863 RCCD1 0.49 4.76 0.39 5.37e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs2243480 0.908 rs4718273 chr7:65216099 G/A cg18252515 chr7:66147081 NA 1.17 7.17 0.54 5.94e-11 Diabetic kidney disease; TGCT trans rs114540395 0.858 rs76114299 chr10:103219315 G/C cg10198749 chr1:39920707 MACF1 0.55 7.12 0.54 7.73e-11 Schizophrenia; TGCT cis rs1023500 0.573 rs6002592 chr22:42476754 A/C cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Schizophrenia; TGCT cis rs11969893 0.737 rs1856131 chr6:101407104 C/G cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs72781680 0.846 rs55770503 chr2:24030126 A/T cg08917208 chr2:24149416 ATAD2B 0.81 4.99 0.41 1.96e-6 Lymphocyte counts; TGCT cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs2963155 0.518 rs258748 chr5:142656454 C/G cg17617527 chr5:142782415 NR3C1 0.86 6.49 0.5 1.82e-9 Breast cancer; TGCT cis rs7916852 0.867 rs7923978 chr10:28389499 C/T cg15286905 chr10:27530250 ACBD5 -0.45 -4.48 -0.37 1.69e-5 Glaucoma (primary open-angle); TGCT cis rs8031584 0.781 rs4779498 chr15:31177476 C/T cg14829155 chr15:31115871 NA -0.38 -4.91 -0.4 2.78e-6 Huntington's disease progression; TGCT cis rs28595532 1.000 rs114039398 chr4:119631627 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs12477438 0.520 rs2309581 chr2:99784292 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.13 -17.67 -0.85 1.16e-35 Chronic sinus infection; TGCT trans rs62103177 0.713 rs62103186 chr18:77627574 G/C cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs2439831 0.681 rs1095386 chr15:43609509 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.69 0.62 1.84e-14 Lung cancer in ever smokers; TGCT cis rs7618915 0.547 rs34173654 chr3:52634605 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg21724239 chr8:58056113 NA 0.47 5.05 0.41 1.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs11247915 1.000 rs11247915 chr1:26650550 G/T cg12742826 chr1:26365331 SLC30A2 0.23 5.18 0.42 8.78e-7 Obesity-related traits; TGCT cis rs17401966 0.540 rs1467653 chr1:10413123 A/G cg19773385 chr1:10388646 KIF1B 0.22 5.19 0.42 8.33e-7 Hepatocellular carcinoma; TGCT cis rs1153858 1.000 rs2114501 chr15:45670316 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs950169 0.800 rs4842847 chr15:84931199 G/A cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs10744422 0.640 rs10847751 chr12:123291742 C/T cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT trans rs2727020 0.523 rs7948958 chr11:49506749 G/A cg11707556 chr5:10655725 ANKRD33B 0.42 8.54 0.61 4.17e-14 Coronary artery disease; TGCT cis rs11677370 0.603 rs11696104 chr2:3849512 C/G cg17052675 chr2:3827356 NA -0.41 -7.0 -0.53 1.39e-10 Type 2 diabetes; TGCT cis rs5769765 0.862 rs9616386 chr22:50313179 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg26531700 chr6:26746687 NA 0.5 4.64 0.38 8.54e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.825 rs9661082 chr1:53245472 A/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs5769707 0.935 rs1109320 chr22:49989106 G/A cg10356904 chr22:49881777 NA -0.23 -4.56 -0.38 1.22e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs12579753 0.869 rs17692407 chr12:82171369 G/C cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs1552244 0.816 rs13076197 chr3:10019773 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs12477438 0.734 rs4851184 chr2:99666434 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs10883723 0.810 rs10748824 chr10:104274466 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 15.75 0.82 2.24e-31 Prudent dietary pattern; TGCT cis rs7726839 0.540 rs12517638 chr5:645484 C/T cg16624210 chr5:671434 TPPP 0.4 4.52 0.38 1.44e-5 Obesity-related traits; TGCT cis rs514406 0.505 rs269286 chr1:53169018 C/T cg25767906 chr1:53392781 SCP2 0.49 5.51 0.44 2.03e-7 Monocyte count; TGCT cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg17554472 chr22:41940697 POLR3H 0.47 5.04 0.41 1.63e-6 Vitiligo; TGCT cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs13424612 0.965 rs34789127 chr2:240952002 C/T cg26363272 chr2:240904871 NDUFA10 0.28 4.77 0.39 5.18e-6 Odorant perception (isobutyraldehyde); TGCT cis rs9583531 0.600 rs754599 chr13:111354788 C/A cg24331049 chr13:111365604 ING1 0.82 8.02 0.58 6.64e-13 Coronary artery disease; TGCT cis rs6969780 0.915 rs3801320 chr7:27164364 C/A cg04321618 chr7:27170880 HOXA4 0.5 4.81 0.4 4.35e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs9646954 0.542 rs4149510 chr2:101023635 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 5.95e-6 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.966 rs28441502 chr4:17598384 G/A cg10189774 chr4:17578691 LAP3 0.62 5.4 0.44 3.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7208859 0.623 rs216433 chr17:28921860 T/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2050392 0.544 rs598672 chr10:30742388 C/T cg13289132 chr10:30722225 MAP3K8 -0.38 -4.69 -0.39 7.08e-6 Inflammatory bowel disease; TGCT cis rs34172651 0.517 rs2287783 chr16:24831727 C/T cg06028605 chr16:24865363 SLC5A11 0.41 4.6 0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg09323728 chr8:95962352 TP53INP1 -0.42 -4.97 -0.41 2.13e-6 Type 2 diabetes; TGCT cis rs9368481 0.729 rs9379948 chr6:26944783 T/G cg26531700 chr6:26746687 NA 0.58 5.45 0.44 2.66e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1008375 0.966 rs10006317 chr4:17702525 A/G cg18681998 chr4:17616180 MED28 0.78 7.37 0.55 2.06e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28595532 0.920 rs17259284 chr4:119779298 T/C cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs6879260 0.928 rs11739624 chr5:179727290 T/C cg23248424 chr5:179741104 GFPT2 -0.35 -6.32 -0.49 4.31e-9 Height; TGCT cis rs7086627 0.515 rs10887903 chr10:82210641 C/T cg01528321 chr10:82214614 TSPAN14 0.65 6.2 0.49 7.74e-9 Post bronchodilator FEV1; TGCT cis rs1532993 0.518 rs6532688 chr4:98604134 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6964587 0.967 rs7781221 chr7:91664645 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs9467773 0.967 rs6941022 chr6:26553531 T/C cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs17741873 0.779 rs10458656 chr10:75592662 A/G cg07699608 chr10:75541558 CHCHD1 0.71 5.02 0.41 1.77e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs7561149 0.580 rs36051007 chr2:179545859 C/T cg12089249 chr2:179345200 MIR548N;PLEKHA3 0.66 5.17 0.42 9.23e-7 QT interval; TGCT cis rs9584850 0.834 rs2031239 chr13:99111560 C/T cg15168958 chr13:99100528 FARP1 -0.24 -4.75 -0.39 5.48e-6 Neuroticism; TGCT cis rs12497850 0.931 rs11924597 chr3:48937790 T/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs3806843 0.766 rs2251860 chr5:140048209 T/C cg19875535 chr5:140030758 IK -0.35 -5.95 -0.47 2.61e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs682748 0.846 rs12656050 chr5:17142224 C/T cg23987134 chr5:17158319 LOC285696 -0.21 -5.19 -0.42 8.4e-7 Hippocampal atrophy; TGCT cis rs3091242 0.900 rs4649086 chr1:25778967 T/A cg00786635 chr1:25594202 NA 0.52 5.56 0.45 1.59e-7 Erythrocyte sedimentation rate; TGCT cis rs7552404 0.727 rs11161626 chr1:76260837 C/T cg22875332 chr1:76189707 ACADM 0.61 6.4 0.5 2.92e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1215050 0.791 rs7681599 chr4:98664109 C/T cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1395 0.710 rs11682913 chr2:27473649 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.65 8.48 0.61 5.54e-14 Blood metabolite levels; TGCT cis rs3753275 0.624 rs6577524 chr1:8856972 C/T cg17029193 chr1:8510607 RERE -0.31 -4.75 -0.39 5.51e-6 Educational attainment; TGCT cis rs34638657 0.732 rs62045963 chr16:82200661 A/G cg09439754 chr16:82129088 HSD17B2 -0.24 -4.63 -0.38 9.27e-6 Lung adenocarcinoma; TGCT cis rs1005277 0.579 rs2474586 chr10:38418882 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6061231 0.793 rs6061512 chr20:60976929 G/A cg24112000 chr20:60950667 NA -0.39 -5.06 -0.41 1.48e-6 Colorectal cancer; TGCT cis rs59107033 0.559 rs60088212 chr3:123105548 G/A cg04890266 chr3:123102914 ADCY5 -0.48 -7.84 -0.58 1.81e-12 Lymphocyte counts; TGCT cis rs9948 0.655 rs76653480 chr2:97375549 C/T cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs950169 0.959 rs12902070 chr15:84793558 T/C cg11189052 chr15:85197271 WDR73 0.73 6.13 0.48 1.06e-8 Schizophrenia; TGCT cis rs9443645 0.901 rs9443632 chr6:79664440 T/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7000551 0.689 rs6993341 chr8:22310933 T/C cg12081754 chr8:22256438 SLC39A14 0.31 5.17 0.42 8.96e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1865760 0.827 rs9461227 chr6:25960815 C/T cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs1215050 0.605 rs13140687 chr4:98640565 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.92 -0.4 2.72e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1372520 0.684 rs1837891 chr4:90736131 C/G cg20003494 chr4:90757398 SNCA 0.63 5.08 0.41 1.37e-6 Neuroticism; TGCT cis rs9486715 1.000 rs6905737 chr6:97066659 A/T cg18709589 chr6:96969512 KIAA0776 -0.78 -7.14 -0.54 6.99e-11 Headache; TGCT cis rs4727027 0.704 rs7787753 chr7:148901779 A/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.53 0.38 1.35e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs1005277 0.579 rs2474608 chr10:38457109 C/T cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.5e-21 Extrinsic epigenetic age acceleration; TGCT cis rs7267979 0.966 rs6050567 chr20:25354561 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg07061783 chr6:25882402 NA -0.46 -4.88 -0.4 3.2e-6 Blood metabolite levels; TGCT cis rs3806843 0.548 rs246038 chr5:140331699 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs910316 0.967 rs12147532 chr14:75651858 T/G cg11812906 chr14:75593930 NEK9 -0.71 -6.76 -0.52 4.84e-10 Height; TGCT cis rs910316 1.000 rs12589876 chr14:75544189 G/A cg23033748 chr14:75592666 NEK9 0.28 4.76 0.39 5.27e-6 Height; TGCT cis rs17221829 0.733 rs11018715 chr11:89394462 A/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT trans rs17685 0.712 rs1859794 chr7:75821544 G/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.78 0.62 1.1e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7681423 0.951 rs6050 chr4:155507590 C/T cg20735720 chr4:155535218 FGG 0.38 5.75 0.46 6.59e-8 Fibrinogen; TGCT cis rs4819852 0.752 rs917478 chr22:19972824 T/C cg07821417 chr22:19972146 ARVCF 0.19 4.56 0.38 1.2e-5 Pulse pressure; TGCT cis rs12477438 0.765 rs4851183 chr2:99629149 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs651907 0.535 rs12633089 chr3:101528763 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.47 0.68 9.24e-19 Colorectal cancer; TGCT cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg07424592 chr7:64974309 NA -0.64 -6.33 -0.49 4.07e-9 Calcium levels; TGCT cis rs208515 0.525 rs10944859 chr6:66665197 A/G cg07460842 chr6:66804631 NA 0.85 8.73 0.62 1.41e-14 Exhaled nitric oxide levels; TGCT cis rs1865760 1.000 rs6910174 chr6:25904414 C/T cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs35146811 0.735 rs6465766 chr7:99785671 A/G cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs28437878 1 rs28437878 chr15:78807872 C/T cg24631222 chr15:78858424 CHRNA5 0.91 7.89 0.58 1.38e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs6964587 0.933 rs6465350 chr7:91768615 G/A cg17063962 chr7:91808500 NA 0.91 9.84 0.66 3.11e-17 Breast cancer; TGCT cis rs7208859 0.623 rs35916850 chr17:29011173 G/A cg13385521 chr17:29058706 SUZ12P 0.75 4.51 0.38 1.5e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11577318 0.579 rs11247934 chr1:26695758 A/T cg14210634 chr1:25870291 LDLRAP1 0.53 4.61 0.38 9.8e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6831352 0.918 rs28987097 chr4:100049579 C/T cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.39 -4.9 -0.4 2.97e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs3820928 0.904 rs6735069 chr2:227893660 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.7 -0.39 6.74e-6 Pulmonary function; TGCT cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs2544527 0.819 rs2693018 chr2:15921554 A/G cg26669897 chr2:15909070 NA 0.42 4.98 0.41 2.09e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs7824557 0.602 rs1435273 chr8:11209499 T/C cg21775007 chr8:11205619 TDH 0.73 6.98 0.53 1.6e-10 Retinal vascular caliber; TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs1862618 0.671 rs2591956 chr5:56244604 G/A cg24531977 chr5:56204891 C5orf35 0.69 7.29 0.55 3.25e-11 Initial pursuit acceleration; TGCT cis rs10504229 0.728 rs17215676 chr8:58152915 G/T cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs2073300 1.000 rs6132631 chr20:23461848 T/C cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs2458413 0.563 rs2458422 chr8:105332817 C/T cg23108931 chr8:105342351 NA -0.35 -6.15 -0.48 9.76e-9 Paget's disease; TGCT cis rs4642101 0.628 rs1003080 chr3:12811628 C/T cg05775895 chr3:12838266 CAND2 -0.67 -6.76 -0.52 4.81e-10 QRS complex (12-leadsum); TGCT cis rs3770081 1.000 rs3770090 chr2:86263288 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.18 -4.81 -0.4 4.33e-6 Facial emotion recognition (sad faces); TGCT cis rs6582630 0.555 rs1906260 chr12:38601013 T/G cg26384229 chr12:38710491 ALG10B 0.9 8.1 0.59 4.36e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs853679 0.567 rs7774981 chr6:28346910 T/C cg18815343 chr6:28367644 ZSCAN12 -0.52 -4.72 -0.39 6.26e-6 Depression; TGCT cis rs10838634 1.000 rs7106323 chr11:46842841 C/A cg18332754 chr11:46939436 LRP4 0.89 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs797680 0.754 rs12044883 chr1:93820575 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.65 -0.45 1.05e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9926296 0.706 rs2159115 chr16:89831819 A/G cg04287289 chr16:89883240 FANCA 0.64 6.38 0.5 3.15e-9 Vitiligo; TGCT cis rs2153535 0.580 rs1410766 chr6:8525360 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs2832191 0.692 rs2245734 chr21:30359965 C/T cg08807101 chr21:30365312 RNF160 0.64 6.05 0.48 1.57e-8 Dental caries; TGCT cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg16680214 chr1:154839983 KCNN3 -0.35 -7.11 -0.54 8.04e-11 Prostate cancer; TGCT cis rs11098499 0.909 rs78332141 chr4:120375782 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg06634786 chr22:41940651 POLR3H 0.87 8.2 0.59 2.56e-13 Vitiligo; TGCT cis rs4077515 0.901 rs3812573 chr9:139276680 C/T cg13741927 chr9:139327495 INPP5E -0.2 -4.76 -0.39 5.37e-6 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs2115630 0.905 rs1975277 chr15:85329558 C/T cg17173187 chr15:85201210 NMB -0.4 -4.93 -0.4 2.56e-6 P wave terminal force; TGCT cis rs3820928 0.874 rs2177594 chr2:227836239 C/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.67 -0.39 7.8e-6 Pulmonary function; TGCT cis rs6912958 0.559 rs445434 chr6:88041849 A/G cg10393598 chr6:87862264 NA -0.31 -4.51 -0.38 1.5e-5 Monocyte percentage of white cells; TGCT cis rs6714710 0.603 rs6746768 chr2:98466647 C/T cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs4372836 0.729 rs4611608 chr2:29064536 A/G cg09522027 chr2:28974177 PPP1CB 0.71 7.46 0.56 1.33e-11 Body mass index; TGCT cis rs12579753 1.000 rs12821073 chr12:82183260 G/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs12950390 0.853 rs12450729 chr17:45855363 A/G cg24803719 chr17:45855879 NA -0.49 -5.01 -0.41 1.8e-6 IgG glycosylation; TGCT cis rs7119 0.667 rs4886889 chr15:77902347 T/C cg27398640 chr15:77910606 LINGO1 0.32 6.76 0.52 4.86e-10 Type 2 diabetes; TGCT cis rs769267 0.930 rs1054930 chr19:19648346 G/C cg08509172 chr19:19383838 TM6SF2 -0.35 -4.49 -0.37 1.62e-5 Tonsillectomy; TGCT cis rs9910055 0.960 rs9911991 chr17:42278916 G/C cg13607699 chr17:42295918 UBTF 0.88 7.82 0.57 1.96e-12 Total body bone mineral density; TGCT cis rs1552244 1.000 rs9875081 chr3:10083935 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs860554 0.705 rs1779301 chr1:201263330 C/G cg01022117 chr1:201258280 PKP1 0.34 5.05 0.41 1.54e-6 Panic disorder; TGCT cis rs3008870 1.000 rs3008853 chr1:67385488 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs12477438 0.501 rs17759607 chr2:99737005 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs7043114 0.525 rs6479416 chr9:95053871 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.57 -0.45 1.53e-7 Height; TGCT cis rs9814567 0.712 rs4955545 chr3:134332926 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.45 -0.5 2.3e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs3849570 0.925 rs13091492 chr3:81891476 A/G cg07356753 chr3:81810745 GBE1 -0.71 -6.2 -0.49 7.85e-9 Waist circumference;Body mass index; TGCT cis rs9296092 0.560 rs62407561 chr6:33528103 T/C cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs28595532 1.000 rs41455648 chr4:119718030 A/G cg14228332 chr4:119757509 SEC24D 1.08 6.04 0.48 1.65e-8 Cannabis dependence symptom count; TGCT cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg02018176 chr4:1364513 KIAA1530 0.29 4.81 0.4 4.34e-6 Longevity; TGCT cis rs6840360 0.571 rs17275536 chr4:152498625 C/T cg17479576 chr4:152424074 FAM160A1 -0.7 -7.47 -0.56 1.28e-11 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.543 rs6446218 chr3:49075513 A/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.3 -0.43 5.13e-7 Parkinson's disease; TGCT cis rs7017914 0.967 rs6472543 chr8:71664408 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs2464469 0.526 rs2899612 chr15:58335867 G/A cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.47 -0.5 2.08e-9 Barrett's esophagus or Esophageal adenocarcinoma; TGCT cis rs7809950 0.817 rs2701679 chr7:107283908 A/G cg23024343 chr7:107201750 COG5 0.44 6.2 0.49 7.8e-9 Coronary artery disease; TGCT cis rs4074961 0.585 rs10752600 chr1:38067552 G/T cg17933807 chr1:38061675 GNL2 1.06 14.95 0.8 1.55e-29 Axial length; TGCT cis rs4638749 0.906 rs34974921 chr2:108860253 A/G cg06795125 chr2:108905320 SULT1C2 -0.37 -4.69 -0.39 6.95e-6 Blood pressure; TGCT cis rs3617 0.625 rs7620690 chr3:52891707 A/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.49 -4.58 -0.38 1.09e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg11494091 chr17:61959527 GH2 -0.41 -7.04 -0.53 1.13e-10 Height; TGCT trans rs751984 0.706 rs7931683 chr11:61263581 T/C cg03305746 chr2:106927199 NA -0.58 -7.01 -0.53 1.32e-10 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs36051895 0.659 rs3780366 chr9:5068596 T/C cg02405213 chr9:5042618 JAK2 -0.77 -10.08 -0.67 8.31e-18 Pediatric autoimmune diseases; TGCT cis rs1775148 1 rs1775148 chr1:205757824 C/T cg24503407 chr1:205819492 PM20D1 0.37 4.44 0.37 2e-5 Prostate cancer; TGCT cis rs8180040 0.764 rs11130115 chr3:47181661 C/A cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT cis rs1375194 0.582 rs13391166 chr2:33805314 C/T cg04131969 chr2:33951647 MYADML 0.56 4.92 0.4 2.7e-6 Response to antidepressants in depression; TGCT cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs6840360 0.548 rs4254751 chr4:152322571 C/T cg17479576 chr4:152424074 FAM160A1 -0.63 -6.8 -0.52 3.99e-10 Intelligence (multi-trait analysis); TGCT cis rs12541335 0.590 rs11136002 chr8:22217082 C/T cg26039829 chr8:22132926 PIWIL2 0.28 5.12 0.42 1.13e-6 Hypertriglyceridemia; TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg01802117 chr1:53393560 SCP2 -0.45 -5.23 -0.43 7e-7 Monocyte count; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg13144432 chr15:100513968 ADAMTS17 -0.7 -6.69 -0.51 6.84e-10 Follicular lymphoma; TGCT cis rs6669284 1.000 rs11119355 chr1:206885839 T/G cg11153969 chr1:207277031 C4BPA -0.21 -4.47 -0.37 1.76e-5 Blood protein levels; TGCT cis rs3008870 1.000 rs912797 chr1:67413478 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.91 0.73 2.83e-22 Lymphocyte percentage of white cells; TGCT trans rs11722228 0.964 rs10939614 chr4:9926613 T/C cg26043149 chr18:55253948 FECH -0.74 -7.46 -0.56 1.33e-11 Gout;Urate levels;Serum uric acid levels; TGCT cis rs1371867 0.817 rs1788185 chr8:101335529 T/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs12142240 0.698 rs966907 chr1:46817125 C/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs9611565 0.546 rs5758430 chr22:42109844 G/T cg03806693 chr22:41940476 POLR3H 1.06 11.92 0.73 2.7e-22 Vitiligo; TGCT cis rs1205863 1.000 rs1205879 chr6:11946831 G/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs2070488 0.775 rs7644530 chr3:38558316 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.89 -0.53 2.46e-10 Electrocardiographic conduction measures; TGCT cis rs9372253 0.967 rs1055301 chr6:110713042 A/G cg01119278 chr6:110721349 DDO -0.34 -5.45 -0.44 2.55e-7 Platelet distribution width; TGCT cis rs13022357 1.000 rs2288111 chr2:160084534 A/G cg00168785 chr2:160142643 WDSUB1 0.46 4.6 0.38 1.04e-5 Sudden cardiac arrest; TGCT cis rs1008375 1.000 rs10440301 chr4:17663199 G/A cg16339924 chr4:17578868 LAP3 0.6 4.98 0.41 2.06e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs981844 0.740 rs6815202 chr4:154682440 A/G cg14289246 chr4:154710475 SFRP2 -0.89 -8.19 -0.59 2.73e-13 Response to statins (LDL cholesterol change); TGCT cis rs10779751 0.770 rs12097293 chr1:11197467 A/G cg08854313 chr1:11322531 MTOR -0.84 -6.81 -0.52 3.82e-10 Body mass index; TGCT cis rs17221829 0.733 rs4753223 chr11:89360653 A/C cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg00101154 chr16:420108 MRPL28 -0.65 -7.45 -0.56 1.36e-11 Bone mineral density (spine);Bone mineral density; TGCT cis rs28595532 0.925 rs28627331 chr4:119665345 T/C cg14228332 chr4:119757509 SEC24D 1.06 5.75 0.46 6.55e-8 Cannabis dependence symptom count; TGCT cis rs4689388 0.856 rs4308430 chr4:6294095 A/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2996428 0.667 rs11576900 chr1:3770914 A/G cg17848003 chr1:3704513 LRRC47 0.18 5.15 0.42 9.99e-7 Red cell distribution width; TGCT cis rs2153535 0.563 rs4428546 chr6:8490376 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg26338869 chr17:61819248 STRADA -0.58 -5.23 -0.43 6.97e-7 Prudent dietary pattern; TGCT cis rs1461503 0.900 rs7110039 chr11:122834001 C/T cg27398637 chr11:122830231 C11orf63 0.39 4.66 0.39 7.97e-6 Menarche (age at onset); TGCT cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT trans rs10768122 0.524 rs7116432 chr11:35244058 C/T cg26098768 chr20:2187533 NA 0.49 7.32 0.55 2.71e-11 Vitiligo; TGCT trans rs2288327 0.643 rs16866334 chr2:179336672 A/G cg18634211 chr1:26737262 LIN28 0.89 7.26 0.55 3.68e-11 Atrial fibrillation; TGCT cis rs2050392 0.590 rs694346 chr10:30711929 C/T cg18806716 chr10:30721971 MAP3K8 -0.71 -9.48 -0.65 2.35e-16 Inflammatory bowel disease; TGCT cis rs9902453 0.740 rs2617867 chr17:28049399 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.39 -0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs11122272 0.735 rs2808584 chr1:231512925 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs6484504 0.576 rs286649 chr11:31230468 C/T cg26647111 chr11:31128758 NA -0.34 -4.73 -0.39 5.88e-6 Red blood cell count; TGCT cis rs10791097 0.694 rs4937583 chr11:130741606 A/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs74910095 0.786 rs73117180 chr5:62939428 A/G cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4689592 0.587 rs6825954 chr4:7074226 T/C cg02503808 chr4:7069936 GRPEL1 1.03 9.64 0.65 9.63e-17 Monocyte percentage of white cells; TGCT cis rs2242116 0.727 rs10865943 chr3:46969970 T/C cg23352942 chr3:46931381 PTH1R -0.35 -5.26 -0.43 6.05e-7 Birth weight; TGCT cis rs11997175 0.574 rs4733456 chr8:33656359 C/T ch.8.33884649F chr8:33765107 NA 0.29 4.69 0.39 6.98e-6 Body mass index; TGCT cis rs7260538 0.808 rs1552219 chr19:41525374 A/G cg20630647 chr19:41531805 NA 0.3 4.82 0.4 4.18e-6 DDT metabolite (p,p'-DDE levels); TGCT cis rs9549367 0.713 rs4907598 chr13:113861385 C/T cg00898013 chr13:113819073 PROZ 0.52 6.6 0.51 1.07e-9 Platelet distribution width; TGCT cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg03264133 chr6:25882463 NA -0.63 -7.09 -0.54 8.95e-11 Blood metabolite levels; TGCT cis rs10875746 0.768 rs4760609 chr12:48415757 A/C cg20731937 chr12:48336164 NA -0.64 -5.7 -0.46 8.29e-8 Longevity (90 years and older); TGCT cis rs453301 0.624 rs2288673 chr8:8860276 G/T cg15556689 chr8:8085844 FLJ10661 0.79 7.14 0.54 6.99e-11 Joint mobility (Beighton score); TGCT cis rs60871478 1.000 rs67721251 chr7:825114 T/C cg15782153 chr7:917662 C7orf20 -0.5 -4.51 -0.38 1.48e-5 Cerebrospinal P-tau181p levels; TGCT trans rs10203711 1.000 rs10191070 chr2:239565413 A/G cg16021909 chr1:248021091 TRIM58 -0.66 -6.62 -0.51 9.76e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs13256369 0.951 rs13270852 chr8:8566853 A/G cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs7552404 0.920 rs1612097 chr1:76218875 C/T cg22875332 chr1:76189707 ACADM 0.71 8.52 0.61 4.59e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1215050 0.904 rs2903153 chr4:99057457 C/T cg17366294 chr4:99064904 C4orf37 0.49 4.89 0.4 3.05e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs950169 0.960 rs35159785 chr15:84804014 G/A cg11189052 chr15:85197271 WDR73 0.78 6.39 0.5 3.08e-9 Schizophrenia; TGCT trans rs7864133 1.000 rs11139254 chr9:84064100 G/A cg23451063 chr7:1059876 C7orf50 0.55 6.93 0.53 2.02e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs1372520 0.935 rs1442152 chr4:90775649 C/A cg20003494 chr4:90757398 SNCA -0.61 -4.88 -0.4 3.15e-6 Neuroticism; TGCT cis rs6747488 0.515 rs599300 chr2:31811306 G/A cg02381751 chr2:32503542 YIPF4 0.47 4.54 0.38 1.3e-5 Interleukin-18 levels; TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg10975897 chr6:15504844 JARID2 0.83 5.21 0.42 7.52e-7 Gambling; TGCT cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs9473924 0.505 rs6908879 chr6:50869856 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs4819052 0.851 rs4819041 chr21:46659955 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.86 0.4 3.49e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1395 0.778 rs6709602 chr2:27405497 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.64 9.02 0.63 2.9e-15 Blood metabolite levels; TGCT cis rs7772486 0.790 rs2254257 chr6:146203724 C/T cg23711669 chr6:146136114 FBXO30 0.91 10.68 0.69 2.77e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs1215050 0.904 rs1727285 chr4:98978821 G/A cg17366294 chr4:99064904 C4orf37 -0.47 -4.67 -0.39 7.61e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs915832 1.000 rs915832 chr21:43275495 C/T cg20533952 chr21:43198601 NA 0.31 4.78 0.39 4.95e-6 Response to taxane treatment (placlitaxel); TGCT cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg02487422 chr3:49467188 NICN1 0.49 4.53 0.38 1.38e-5 Menarche (age at onset); TGCT cis rs1062177 0.694 rs2915816 chr5:151115857 G/A cg12924095 chr5:151150029 G3BP1 -0.33 -4.73 -0.39 5.96e-6 Preschool internalizing problems; TGCT cis rs6088590 1.000 rs6088615 chr20:33400474 C/T cg24642439 chr20:33292090 TP53INP2 -0.62 -5.66 -0.45 1.01e-7 Coronary artery disease; TGCT cis rs7605378 0.688 rs769961 chr2:200712141 C/A cg23649088 chr2:200775458 C2orf69 0.44 7.65 0.57 4.82e-12 Osteoporosis; TGCT cis rs3784262 1.000 rs10851630 chr15:58242148 C/T cg12031962 chr15:58353849 ALDH1A2 -0.48 -7.31 -0.55 2.94e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7208859 0.573 rs7222803 chr17:29119897 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs9311474 0.575 rs4434138 chr3:52556890 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.55 5.08 0.42 1.35e-6 Electroencephalogram traits; TGCT cis rs2153904 0.793 rs71633563 chr1:205735854 C/T cg23034840 chr1:205782522 SLC41A1 -0.84 -5.07 -0.41 1.39e-6 Prostate-specific antigen levels; TGCT cis rs6840360 0.615 rs2406973 chr4:152608339 G/T cg17479576 chr4:152424074 FAM160A1 0.55 5.47 0.44 2.37e-7 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg03517284 chr6:25882590 NA -0.68 -7.27 -0.55 3.53e-11 Blood metabolite levels; TGCT cis rs896854 0.812 rs4582532 chr8:95969257 G/A cg09323728 chr8:95962352 TP53INP1 -0.54 -6.89 -0.53 2.54e-10 Type 2 diabetes; TGCT cis rs9910055 0.593 rs58392387 chr17:42297889 A/G cg19774624 chr17:42201019 HDAC5 -0.72 -6.64 -0.51 8.87e-10 Total body bone mineral density; TGCT cis rs35264875 1.000 rs7110274 chr11:68842704 A/G cg02660097 chr11:68866761 NA 0.32 4.77 0.39 5e-6 Blond vs. brown hair color; TGCT cis rs6089584 0.888 rs6061973 chr20:60610870 C/T cg13770153 chr20:60521292 NA -0.54 -6.99 -0.53 1.51e-10 Body mass index; TGCT cis rs67478160 0.584 rs12433009 chr14:104196405 C/G cg01849466 chr14:104193079 ZFYVE21 -0.19 -4.56 -0.38 1.22e-5 Schizophrenia; TGCT cis rs7666738 0.830 rs11735193 chr4:98761900 C/T cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9653442 0.547 rs1062143 chr2:100659796 A/G cg07810366 chr2:100720526 AFF3 -0.41 -6.86 -0.52 2.94e-10 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7119 0.717 rs12899390 chr15:77815238 A/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs1371867 0.817 rs1660314 chr8:101332953 C/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs7085104 0.572 rs284858 chr10:104573936 T/C cg05855489 chr10:104503620 C10orf26 -0.63 -6.21 -0.49 7.3e-9 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs1577917 0.958 rs12212480 chr6:86458777 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.53 -0.44 1.8e-7 Response to antipsychotic treatment; TGCT cis rs2933343 0.679 rs1091938 chr3:128637025 T/C cg11901034 chr3:128598214 ACAD9 -0.66 -6.54 -0.51 1.42e-9 IgG glycosylation; TGCT cis rs7412746 0.658 rs4970982 chr1:150865084 G/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs9419702 0.526 rs9419637 chr10:133548059 T/C cg04492858 chr10:133558786 NA 0.56 6.0 0.47 1.98e-8 Survival in rectal cancer; TGCT cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg16520312 chr17:43971471 MAPT;LOC100128977 -0.64 -5.6 -0.45 1.32e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2692947 0.644 rs1724125 chr2:96831355 G/A cg23100626 chr2:96804247 ASTL 0.46 5.24 0.43 6.79e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7781977 0.723 rs11765436 chr7:50344077 T/A cg01139861 chr7:50343298 IKZF1 0.51 5.37 0.43 3.72e-7 IgG glycosylation; TGCT cis rs10984561 0.881 rs7032141 chr9:122253998 A/G cg14242995 chr9:122249943 NA 0.76 5.51 0.44 2e-7 Pulmonary function decline; TGCT cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg05785598 chr3:49045655 WDR6 0.36 4.81 0.4 4.24e-6 Menarche (age at onset); TGCT cis rs35146811 0.695 rs858509 chr7:99821470 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs7659604 0.539 rs11098648 chr4:122759872 C/T cg20573242 chr4:122745356 CCNA2 0.64 5.62 0.45 1.22e-7 Type 2 diabetes; TGCT cis rs904251 0.523 rs2776874 chr6:37483197 C/T cg01843034 chr6:37503916 NA -0.5 -7.0 -0.53 1.42e-10 Cognitive performance; TGCT cis rs367943 0.901 rs463167 chr5:112799369 C/A cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs2180341 1.000 rs9375499 chr6:127618072 T/C cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs6665290 0.904 rs10916075 chr1:227184074 G/A cg10327440 chr1:227177885 CDC42BPA -0.98 -19.78 -0.87 3.72e-40 Myeloid white cell count; TGCT cis rs12893668 0.637 rs4525427 chr14:104072793 C/A cg26031613 chr14:104095156 KLC1 -0.55 -4.64 -0.38 8.81e-6 Reticulocyte count; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs13256369 1.000 rs7820159 chr8:8576215 T/C cg06671706 chr8:8559999 CLDN23 0.35 4.69 0.39 7e-6 Obesity-related traits; TGCT cis rs9517320 0.517 rs4772097 chr13:99194652 C/A cg07423050 chr13:99094983 FARP1 -0.29 -5.54 -0.45 1.69e-7 Longevity; TGCT cis rs9372498 0.908 rs56255677 chr6:118695402 A/G cg21191810 chr6:118973309 C6orf204 -0.5 -4.61 -0.38 9.92e-6 Diastolic blood pressure; TGCT cis rs79349575 0.783 rs2088139 chr17:47000110 C/T cg07967210 chr17:47022446 SNF8 0.42 5.86 0.47 3.86e-8 Type 2 diabetes; TGCT cis rs6542838 0.641 rs6724477 chr2:99537074 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 0.59 5.58 0.45 1.43e-7 Fear of minor pain; TGCT cis rs7845219 0.544 rs2945554 chr8:95939594 C/A cg13393036 chr8:95962371 TP53INP1 -0.46 -5.34 -0.43 4.29e-7 Type 2 diabetes; TGCT cis rs9393692 0.905 rs9357004 chr6:26303319 A/G cg05868516 chr6:26286170 HIST1H4H 0.62 5.69 0.46 8.66e-8 Educational attainment; TGCT cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs12468579 0.503 rs17748980 chr2:191830805 A/C cg21497043 chr2:191745649 GLS 0.51 4.66 0.39 8.05e-6 JT interval (sulfonylurea treatment interaction); TGCT cis rs7017914 0.967 rs13254908 chr8:71626098 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs17473412 0.784 rs114648199 chr5:122702577 A/T cg15125798 chr5:122621645 NA -0.57 -4.83 -0.4 3.88e-6 Total body bone mineral density; TGCT cis rs2721195 0.614 rs12719778 chr8:145879883 T/C cg11211951 chr8:145729740 GPT 0.23 5.11 0.42 1.2e-6 Age at first birth; TGCT cis rs56104184 0.775 rs55737338 chr19:49403141 A/G cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2075371 0.863 rs34231360 chr7:133944988 A/C cg11752832 chr7:134001865 SLC35B4 0.66 5.51 0.44 1.95e-7 Mean platelet volume; TGCT cis rs9393692 0.905 rs9366649 chr6:26329103 A/T cg13736514 chr6:26305472 NA 0.38 5.48 0.44 2.26e-7 Educational attainment; TGCT cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2688608 0.967 rs72814394 chr10:75656325 C/T cg04320760 chr10:75533139 FUT11 -0.3 -4.58 -0.38 1.1e-5 Inflammatory bowel disease; TGCT cis rs1580019 0.539 rs11769109 chr7:32571352 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.14 15.01 0.8 1.13e-29 Cognitive ability; TGCT cis rs9900497 0.604 rs12949049 chr17:19653310 A/G cg22552966 chr17:19620595 SLC47A2 0.23 5.52 0.44 1.93e-7 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs13217239 0.646 rs10456352 chr6:26990358 A/T cg26531700 chr6:26746687 NA 0.69 6.94 0.53 1.9e-10 Schizophrenia; TGCT cis rs3008870 1.000 rs2985825 chr1:67412822 T/G cg11518657 chr1:67396239 MIER1 0.54 4.65 0.39 8.44e-6 Lymphocyte percentage of white cells; TGCT cis rs514406 0.825 rs487453 chr1:53271225 T/C cg25767906 chr1:53392781 SCP2 0.5 5.77 0.46 5.99e-8 Monocyte count; TGCT cis rs7714584 0.793 rs35707106 chr5:150225377 G/A cg22134413 chr5:150180641 NA 0.89 7.04 0.53 1.14e-10 Crohn's disease; TGCT cis rs453301 0.653 rs1562211 chr8:8902424 A/G cg06636001 chr8:8085503 FLJ10661 -0.86 -7.91 -0.58 1.21e-12 Joint mobility (Beighton score); TGCT cis rs7959452 0.535 rs7135092 chr12:69658330 T/C cg11871910 chr12:69753446 YEATS4 0.63 6.24 0.49 6.36e-9 Blood protein levels; TGCT cis rs2456568 0.805 rs55649862 chr11:93682888 G/T cg14065697 chr11:93583672 C11orf90 -0.38 -4.58 -0.38 1.13e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6456156 0.792 rs9366089 chr6:167512896 A/G cg07741184 chr6:167504864 NA 0.23 4.58 0.38 1.09e-5 Primary biliary cholangitis; TGCT cis rs6912958 0.703 rs9359748 chr6:88095500 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.4 5.28 0.43 5.56e-7 Monocyte percentage of white cells; TGCT cis rs7119038 0.774 rs11217037 chr11:118677086 G/A cg19308663 chr11:118741387 NA 0.31 6.43 0.5 2.56e-9 Sjögren's syndrome; TGCT cis rs736408 0.812 rs2071506 chr3:52826276 T/C cg10802521 chr3:52805072 NEK4 -0.68 -7.79 -0.57 2.28e-12 Bipolar disorder; TGCT cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs12510870 0.634 rs13103378 chr4:74379585 A/T cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs7027203 0.576 rs11790754 chr9:96535709 T/G cg14598338 chr9:96623480 NA 0.49 7.07 0.54 9.96e-11 DNA methylation (variation); TGCT cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -5.0 -0.41 1.92e-6 Bipolar disorder; TGCT cis rs10540 1.000 rs12794284 chr11:477623 C/T cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs57590327 0.503 rs6800295 chr3:81593011 A/G cg07356753 chr3:81810745 GBE1 -0.61 -5.1 -0.42 1.24e-6 Extraversion; TGCT cis rs6964587 1.000 rs2269727 chr7:91752690 C/A cg22709100 chr7:91322751 NA 0.29 4.69 0.39 6.98e-6 Breast cancer; TGCT cis rs4927850 0.666 rs4927853 chr3:195752053 G/C cg02975922 chr3:195473998 MUC4 -0.24 -4.58 -0.38 1.11e-5 Pancreatic cancer; TGCT cis rs6598955 0.640 rs1577507 chr1:26547179 C/T cg04990556 chr1:26633338 UBXN11 -0.89 -11.55 -0.72 2.18e-21 Obesity-related traits; TGCT cis rs769267 0.930 rs10419912 chr19:19597055 A/G cg08509172 chr19:19383838 TM6SF2 0.35 4.6 0.38 1.02e-5 Tonsillectomy; TGCT cis rs4285028 0.696 rs3915060 chr3:121712980 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.76 6.39 0.5 3.09e-9 Multiple sclerosis; TGCT cis rs36051895 0.589 rs2224571 chr9:5196253 A/C cg02405213 chr9:5042618 JAK2 -0.75 -9.97 -0.67 1.53e-17 Pediatric autoimmune diseases; TGCT cis rs7568458 0.846 rs10179195 chr2:85762761 A/G cg17127132 chr2:85788382 GGCX 0.63 5.94 0.47 2.65e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2721195 0.967 rs11777703 chr8:145703508 G/A cg17328964 chr8:145687451 CYHR1 0.41 5.81 0.46 4.92e-8 Age at first birth; TGCT cis rs9549260 0.709 rs4581585 chr13:41203905 C/T cg21288729 chr13:41239152 FOXO1 0.97 10.16 0.67 5.23e-18 Red blood cell count; TGCT cis rs2404602 0.692 rs10444858 chr15:76962504 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs9291683 0.566 rs13144709 chr4:10044182 C/T cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Bone mineral density; TGCT cis rs6500602 0.702 rs11076835 chr16:4549618 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.65 0.45 1.06e-7 Schizophrenia; TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs829883 0.664 rs829874 chr12:98840615 G/A cg25150519 chr12:98850993 NA 0.62 7.36 0.55 2.2e-11 Colorectal adenoma (advanced); TGCT cis rs2486288 0.587 rs12899942 chr15:45547280 T/C cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs9527 0.535 rs4917999 chr10:104963051 C/G cg15744005 chr10:104629667 AS3MT 0.42 4.72 0.39 6.34e-6 Arsenic metabolism; TGCT cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs9357506 1.000 rs11758843 chr6:46303340 A/G cg21115430 chr6:46460003 NA -0.27 -5.47 -0.44 2.43e-7 Body mass index; TGCT cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs12540874 0.698 rs12718574 chr7:50573848 G/C cg18232548 chr7:50535776 DDC -0.37 -6.43 -0.5 2.46e-9 Systemic sclerosis; TGCT cis rs2932538 0.922 rs6668533 chr1:113064468 C/T cg22162597 chr1:113214053 CAPZA1 0.27 5.91 0.47 3.05e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1334894 1.000 rs747411 chr6:35586373 G/A cg24281267 chr6:35479648 TULP1 -0.43 -4.69 -0.39 7.09e-6 Coronary artery disease; TGCT cis rs7000551 0.751 rs2443505 chr8:22375341 G/A cg12081754 chr8:22256438 SLC39A14 0.31 5.0 0.41 1.9e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.57 5.14 0.42 1.03e-6 Height; TGCT cis rs7809950 0.678 rs2237660 chr7:106862963 T/A cg23024343 chr7:107201750 COG5 -0.44 -5.92 -0.47 2.97e-8 Coronary artery disease; TGCT cis rs6733011 0.578 rs10172158 chr2:99509605 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.78 -0.39 4.87e-6 Bipolar disorder; TGCT cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9926296 0.542 rs12599531 chr16:89909401 C/T cg26513180 chr16:89883248 FANCA -0.7 -6.41 -0.5 2.71e-9 Vitiligo; TGCT cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg06634786 chr22:41940651 POLR3H 0.89 8.81 0.62 9.46e-15 Vitiligo; TGCT cis rs875971 1.000 rs7781698 chr7:65896312 A/T cg11764359 chr7:65958608 NA 0.6 5.29 0.43 5.36e-7 Aortic root size; TGCT cis rs12762955 0.561 rs7918118 chr10:1042823 C/A cg20503657 chr10:835505 NA -0.4 -5.21 -0.42 7.61e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs9660992 0.626 rs1172113 chr1:205226288 T/C cg00857998 chr1:205179979 DSTYK 0.48 4.46 0.37 1.85e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg23131131 chr22:24373011 LOC391322 -0.81 -9.09 -0.63 1.99e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9457247 0.905 rs377232 chr6:167409638 C/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.3e-6 Crohn's disease; TGCT cis rs10089 1.000 rs4836369 chr5:127486462 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.64e-13 Ileal carcinoids; TGCT cis rs7959452 0.536 rs4761237 chr12:69776461 C/G cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs7760949 0.963 rs9475771 chr6:13914869 A/G cg27413430 chr6:13925136 RNF182 -0.57 -5.5 -0.44 2.09e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs514406 0.763 rs9988539 chr1:53213884 T/C cg01802117 chr1:53393560 SCP2 0.44 5.26 0.43 6.2e-7 Monocyte count; TGCT cis rs875971 0.862 rs1167390 chr7:65575893 G/A cg11764359 chr7:65958608 NA -0.53 -4.68 -0.39 7.26e-6 Aortic root size; TGCT cis rs28595532 0.920 rs17325129 chr4:119778284 T/C cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs4319547 0.695 rs4758643 chr12:122924819 A/T cg08088222 chr12:122070432 ORAI1 0.26 4.46 0.37 1.84e-5 Body mass index; TGCT cis rs7666738 0.830 rs4699595 chr4:99012827 A/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.592 rs2955367 chr17:18024266 T/G cg04398451 chr17:18023971 MYO15A -0.39 -6.89 -0.53 2.55e-10 Total body bone mineral density; TGCT cis rs807669 0.802 rs762528 chr22:19166680 A/G cg02655711 chr22:19163373 SLC25A1 0.42 10.1 0.67 7.26e-18 Metabolite levels; TGCT cis rs1903068 0.719 rs9284955 chr4:56003117 A/G cg09978860 chr4:56023921 NA -0.55 -5.76 -0.46 6.21e-8 Endometriosis; TGCT cis rs9311474 0.652 rs411457 chr3:52228150 A/T cg07507251 chr3:52567010 NT5DC2 -0.37 -4.91 -0.4 2.83e-6 Electroencephalogram traits; TGCT cis rs909674 0.515 rs9611170 chr22:39784845 G/C cg24399712 chr22:39784796 NA -1.07 -13.16 -0.76 2.73e-25 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs6490294 0.904 rs73426401 chr12:112423286 C/T cg10833066 chr12:111807467 FAM109A 0.35 5.13 0.42 1.09e-6 Mean platelet volume; TGCT cis rs62229266 0.654 rs62230787 chr21:37376480 A/G cg08632701 chr21:37451849 NA -0.16 -5.15 -0.42 1e-6 Mitral valve prolapse; TGCT cis rs250677 0.652 rs250670 chr5:148446646 G/T cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs7945705 0.902 rs7479407 chr11:9023421 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.08 0.41 1.38e-6 Hemoglobin concentration; TGCT cis rs7191439 0.789 rs4598894 chr16:88776141 G/A cg27087555 chr16:88793112 FAM38A -0.52 -6.0 -0.47 2.05e-8 Plateletcrit; TGCT cis rs12712073 0.512 rs6710355 chr2:100699994 T/C cg07810366 chr2:100720526 AFF3 -0.38 -5.46 -0.44 2.49e-7 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs12105399 chr2:43676939 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9430161 0.579 rs6696575 chr1:11037136 G/A cg02454025 chr1:11042201 C1orf127 0.92 11.24 0.71 1.21e-20 Ewing sarcoma; TGCT cis rs8180040 0.676 rs66564457 chr3:47020072 G/A cg27129171 chr3:47204927 SETD2 0.73 9.42 0.65 3.15e-16 Colorectal cancer; TGCT cis rs912057 0.671 rs1294428 chr6:6744623 A/G cg06612196 chr6:6737390 NA 0.47 6.77 0.52 4.57e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs6121246 0.567 rs6060344 chr20:30207316 A/G cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs17376456 0.877 rs10072592 chr5:93405989 C/G cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs4455778 0.580 rs5009336 chr7:49116299 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs694739 0.796 rs479777 chr11:64107477 A/G cg02228329 chr11:64053129 BAD;GPR137 0.65 6.11 0.48 1.16e-8 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs208520 1.000 rs12193164 chr6:66978962 C/T cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs7772486 0.743 rs9403742 chr6:146060193 A/C cg23711669 chr6:146136114 FBXO30 0.83 8.91 0.62 5.47e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg21724239 chr8:58056113 NA -0.5 -5.43 -0.44 2.9e-7 Developmental language disorder (linguistic errors); TGCT cis rs3125734 0.633 rs4561099 chr10:64041163 T/C cg19640130 chr10:64028056 RTKN2 -0.38 -4.87 -0.4 3.36e-6 Rheumatoid arthritis; TGCT cis rs7760949 0.889 rs9475816 chr6:13935425 T/C cg27413430 chr6:13925136 RNF182 0.73 6.79 0.52 4.22e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs10771431 0.967 rs7137443 chr12:9372029 C/T cg08997352 chr12:9597637 DDX12 -0.27 -5.55 -0.45 1.65e-7 Breast size; TGCT cis rs273218 0.573 rs16882051 chr5:53342979 T/C ch.5.1024479R chr5:53302184 ARL15 -0.71 -5.67 -0.45 9.67e-8 Migraine; TGCT cis rs1568889 0.938 rs7128045 chr11:28190180 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 8.17 0.59 3.04e-13 Bipolar disorder; TGCT cis rs7103648 0.630 rs7934481 chr11:47883337 C/T cg20307385 chr11:47447363 PSMC3 0.76 7.16 0.54 6.36e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs826838 0.967 rs11183622 chr12:38792849 T/C cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs7666738 0.783 rs10028584 chr4:98962404 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6940638 0.615 rs9393801 chr6:27242681 A/G cg15659132 chr6:26577336 NA -0.59 -5.57 -0.45 1.48e-7 Intelligence (multi-trait analysis); TGCT cis rs6095298 0.553 rs4810882 chr20:47437220 C/A cg12307787 chr20:48099359 KCNB1 0.43 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.613 rs6456708 chr6:26032847 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.75 8.23 0.59 2.21e-13 Intelligence (multi-trait analysis); TGCT cis rs17767294 0.614 rs72849210 chr6:28180459 C/T cg08851530 chr6:28072375 NA 1.46 6.76 0.52 4.79e-10 Parkinson's disease; TGCT cis rs12908161 0.959 rs34784022 chr15:85231906 T/C cg12863693 chr15:85201151 NMB 0.46 5.53 0.44 1.79e-7 Schizophrenia; TGCT cis rs10927875 0.541 rs1739843 chr1:16343254 T/C cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs2153535 0.580 rs6927589 chr6:8456632 A/G cg07606381 chr6:8435919 SLC35B3 -0.53 -4.94 -0.41 2.47e-6 Motion sickness; TGCT cis rs9486719 1.000 rs13202675 chr6:97028427 C/T cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg27286337 chr10:134555280 INPP5A 0.41 4.9 0.4 2.97e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3845702 0.736 rs6733426 chr2:180830958 A/G cg01881094 chr2:180872142 CWC22 -1.05 -6.78 -0.52 4.27e-10 Schizophrenia; TGCT cis rs6430585 0.528 rs309119 chr2:136710372 T/C cg07169764 chr2:136633963 MCM6 1.2 11.66 0.72 1.18e-21 Corneal structure; TGCT cis rs9914988 0.832 rs12946132 chr17:27157362 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs6163 0.588 rs10786706 chr10:104500659 C/T cg05855489 chr10:104503620 C10orf26 1.01 12.87 0.76 1.39e-24 Waist circumference;Hip circumference; TGCT cis rs28735056 0.563 rs55642704 chr18:77688124 C/T cg20368463 chr18:77673604 PQLC1 -0.44 -5.15 -0.42 9.9e-7 Schizophrenia; TGCT cis rs7843479 0.601 rs1058486 chr8:21862551 A/G cg17168535 chr8:21777572 XPO7 0.81 8.25 0.6 1.91e-13 Mean corpuscular volume; TGCT cis rs713587 0.967 rs6752378 chr2:25150116 C/A cg01884057 chr2:25150051 NA 0.4 8.24 0.59 2.05e-13 Body mass index in non-asthmatics; TGCT cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg10862848 chr6:42927986 GNMT -0.4 -4.95 -0.41 2.37e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT trans rs1005277 0.579 rs1740749 chr10:38521646 A/G cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs6582630 0.555 rs8189479 chr12:38308240 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4366490 0.848 rs7106537 chr11:62905841 G/A cg21002970 chr11:62369079 MTA2 0.87 4.67 0.39 7.78e-6 Conotruncal heart defects; TGCT cis rs78487399 0.808 rs13416978 chr2:43705265 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.41 5.64 0.45 1.1e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1903068 0.657 rs73236104 chr4:55990954 G/C cg01777861 chr4:56023843 NA 0.52 5.58 0.45 1.44e-7 Endometriosis; TGCT cis rs138249 0.934 rs138228 chr22:50557120 A/C cg24864161 chr22:50528282 MOV10L1 -0.47 -5.02 -0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs2288884 1.000 rs11669540 chr19:52549739 C/A cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs11644362 0.903 rs2014726 chr16:12992849 T/C cg06890432 chr16:12997467 SHISA9 -0.61 -6.77 -0.52 4.49e-10 Positive affect;Subjective well-being; TGCT cis rs2816062 0.813 rs2745321 chr1:18889198 G/C cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs2445762 0.559 rs4774585 chr15:51616480 G/A cg00184732 chr15:51633821 GLDN 0.52 5.28 0.43 5.54e-7 Hormone measurements; TGCT cis rs11098499 0.754 rs1980025 chr4:120252806 A/G cg09307838 chr4:120376055 NA -0.63 -5.86 -0.47 3.84e-8 Corneal astigmatism; TGCT cis rs797680 0.822 rs6541401 chr1:93738948 G/A cg17826107 chr1:92977322 EVI5 0.23 5.11 0.42 1.2e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs34172651 0.517 rs35560136 chr16:24788915 T/A cg06028605 chr16:24865363 SLC5A11 0.4 4.45 0.37 1.91e-5 Intelligence (multi-trait analysis); TGCT cis rs13394619 0.533 rs12615856 chr2:11746177 C/T cg07314298 chr2:11723111 GREB1 0.29 4.93 0.4 2.59e-6 Endometriosis; TGCT cis rs11098499 0.691 rs28396837 chr4:120271541 G/A cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.05e-7 Corneal astigmatism; TGCT cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs62103177 0.810 rs62103191 chr18:77628769 C/G cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs11785400 0.762 rs2280880 chr8:143721929 C/A cg10596483 chr8:143751796 JRK 0.53 5.03 0.41 1.68e-6 Schizophrenia; TGCT cis rs4631830 0.720 rs113082846 chr10:51502802 G/C cg10326726 chr10:51549505 MSMB -0.23 -4.68 -0.39 7.43e-6 Prostate-specific antigen levels; TGCT cis rs9911578 0.835 rs58647683 chr17:56483194 T/C cg12560992 chr17:57184187 TRIM37 -0.78 -9.12 -0.63 1.72e-15 Intelligence (multi-trait analysis); TGCT cis rs17711722 1.000 rs17711722 chr7:65271197 C/T cg18876405 chr7:65276391 NA -0.37 -5.88 -0.47 3.63e-8 Calcium levels; TGCT cis rs875971 1.000 rs7789768 chr7:65938980 A/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs3812831 0.654 rs9314900 chr13:114937618 A/C cg06611532 chr13:114900021 NA 0.29 5.45 0.44 2.6e-7 Schizophrenia; TGCT trans rs1005277 0.522 rs200943 chr10:38148730 A/G cg17830980 chr10:43048298 ZNF37B -0.74 -8.59 -0.61 3.11e-14 Extrinsic epigenetic age acceleration; TGCT cis rs7666738 0.830 rs7667796 chr4:99071415 G/T cg17366294 chr4:99064904 C4orf37 -0.74 -7.39 -0.55 1.93e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12210905 0.541 rs62617138 chr6:27463766 C/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs6988636 1.000 rs60827294 chr8:124187842 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs6669072 0.647 rs814547 chr1:91238821 T/C cg08895590 chr1:91227319 NA -0.33 -4.58 -0.38 1.14e-5 Cognitive function; TGCT cis rs1371867 0.775 rs3020183 chr8:101233297 A/T cg06002616 chr8:101225028 SPAG1 0.52 5.91 0.47 3.1e-8 Atrioventricular conduction; TGCT cis rs2115630 1.000 rs6496452 chr15:85372645 A/T cg11189052 chr15:85197271 WDR73 -0.66 -6.44 -0.5 2.42e-9 P wave terminal force; TGCT cis rs9467773 0.967 rs1056347 chr6:26527524 G/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs3020736 0.500 rs6002601 chr22:42489058 A/T cg15557168 chr22:42548783 NA 0.22 5.54 0.45 1.73e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11098499 0.863 rs3822194 chr4:120471648 A/G cg09307838 chr4:120376055 NA 0.72 6.87 0.52 2.81e-10 Corneal astigmatism; TGCT cis rs9303401 0.614 rs34843288 chr17:57103140 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.87 0.47 3.77e-8 Cognitive test performance; TGCT cis rs686320 1.000 rs72643572 chr11:65250967 A/G cg00206168 chr11:65308501 LTBP3 0.76 4.66 0.39 8.07e-6 Hip circumference adjusted for BMI; TGCT cis rs6430585 0.583 rs3769008 chr2:136586183 C/T cg07169764 chr2:136633963 MCM6 1.18 11.26 0.71 1.09e-20 Corneal structure; TGCT cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg17971929 chr21:40555470 PSMG1 -0.71 -6.26 -0.49 5.78e-9 Cognitive function; TGCT cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.710 rs80100685 chr2:43650413 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.46 -5.5 -0.44 2.07e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs5167 0.820 rs204468 chr19:45490636 T/C cg09555818 chr19:45449301 APOC2 -0.23 -4.77 -0.39 5.01e-6 Blood protein levels; TGCT cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs10771431 0.967 rs7137443 chr12:9372029 C/T cg21349645 chr12:9436242 LOC642846 -0.42 -4.44 -0.37 1.96e-5 Breast size; TGCT cis rs7727544 0.684 rs272889 chr5:131665378 A/G cg24060327 chr5:131705240 SLC22A5 -0.59 -6.48 -0.5 1.92e-9 Blood metabolite levels; TGCT cis rs11577318 0.626 rs11806568 chr1:26686837 C/A cg14210634 chr1:25870291 LDLRAP1 0.54 4.73 0.39 6.06e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7267979 0.868 rs6138553 chr20:25239233 G/A cg14121845 chr20:25566513 NINL 0.51 5.55 0.45 1.63e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6938 0.534 rs1130741 chr15:75189930 A/G cg09165964 chr15:75287851 SCAMP5 0.56 5.29 0.43 5.31e-7 Breast cancer; TGCT cis rs7246657 0.722 rs2909093 chr19:38199462 T/C cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs4862750 0.914 rs1991255 chr4:187875340 G/A cg11301795 chr4:187892539 NA -0.36 -5.57 -0.45 1.52e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs933688 1.000 rs10058025 chr5:90689052 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.05 0.59 5.84e-13 Smoking behavior; TGCT cis rs6740322 0.748 rs6732337 chr2:43462822 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.4 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.01 0.48 1.89e-8 Bipolar disorder; TGCT cis rs9818758 0.882 rs74926817 chr3:49378833 C/G cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.59 0.38 1.08e-5 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.11 14.83 0.8 3.1e-29 Height; TGCT cis rs76473307 1.000 rs117547698 chr20:57376104 A/G cg06163629 chr20:57414884 GNASAS;GNAS -0.7 -4.61 -0.38 1.01e-5 Chronic lymphocytic leukemia; TGCT cis rs10876993 0.928 rs813854 chr12:58071347 A/G cg15848620 chr12:58087721 OS9 -0.72 -5.83 -0.46 4.52e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs6495367 0.898 rs1443657 chr15:79386946 C/A cg17916960 chr15:79447300 NA 0.37 5.28 0.43 5.69e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.754 rs9399567 chr6:146147295 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.63 -0.38 9.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7208859 0.623 rs9890558 chr17:29110355 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6089584 0.924 rs6142906 chr20:60552554 G/C cg13770153 chr20:60521292 NA -0.46 -5.81 -0.46 4.88e-8 Body mass index; TGCT cis rs4919694 1.000 rs11191525 chr10:104793435 G/C cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs9393777 0.546 rs9366673 chr6:26893329 C/G cg10547057 chr6:26987810 LOC100270746;C6orf41 -0.64 -4.82 -0.4 4.11e-6 Intelligence (multi-trait analysis); TGCT cis rs3749237 0.595 rs4855877 chr3:49448527 T/C cg07636037 chr3:49044803 WDR6 0.63 5.97 0.47 2.36e-8 Resting heart rate; TGCT cis rs6688613 0.649 rs2294195 chr1:166838281 T/C cg07049167 chr1:166818506 POGK 0.25 5.23 0.43 6.88e-7 Refractive astigmatism; TGCT cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs57677839 1 rs57677839 chr11:17028189 G/A cg15378786 chr11:17036137 PLEKHA7 1.03 15.95 0.82 8.09e-32 Coronary artery disease; TGCT cis rs9952991 0.941 rs2847278 chr18:12778715 C/T cg23598886 chr18:12777645 NA 0.62 5.9 0.47 3.25e-8 Inflammatory skin disease; TGCT cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg11062466 chr8:58055876 NA 0.46 4.91 0.4 2.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.790 rs9376970 chr6:146241472 A/C cg23711669 chr6:146136114 FBXO30 -0.88 -10.27 -0.68 2.84e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs3806843 0.576 rs246034 chr5:140332064 A/C cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs3820068 0.705 rs7533125 chr1:15883744 T/C cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs9357506 0.935 rs11965941 chr6:46302727 A/G cg21115430 chr6:46460003 NA -0.27 -5.47 -0.44 2.43e-7 Body mass index; TGCT cis rs12477438 0.501 rs6751927 chr2:99740175 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.22 0.85 7.28e-37 Chronic sinus infection; TGCT cis rs9611519 0.929 rs9611474 chr22:41434858 G/A cg13695892 chr22:41940480 POLR3H -0.53 -4.62 -0.38 9.54e-6 Neuroticism; TGCT cis rs6500602 0.826 rs11076831 chr16:4460133 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.43 -6.72 -0.52 5.78e-10 Schizophrenia; TGCT cis rs11190604 0.767 rs11190509 chr10:102156208 G/A cg16005271 chr10:102321736 NA 0.46 4.72 0.39 6.25e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.683 rs11787247 chr8:58131528 G/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7833790 0.777 rs6473301 chr8:82691340 A/G cg27398817 chr8:82754497 SNX16 -0.83 -5.96 -0.47 2.43e-8 Diastolic blood pressure; TGCT cis rs11122272 0.735 rs2474630 chr1:231535335 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.64 -0.51 8.59e-10 Hemoglobin concentration; TGCT trans rs7698623 0.850 rs2045834 chr4:88800642 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.61 -0.51 1.01e-9 Cardiovascular disease risk factors; TGCT cis rs2046867 0.908 rs11927126 chr3:72806622 A/G cg25664220 chr3:72788482 NA -0.55 -6.96 -0.53 1.75e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs73110464 0.609 rs4919752 chr12:53359229 G/C cg14581129 chr12:53358946 NA -0.63 -6.81 -0.52 3.68e-10 Cancer (pleiotropy); TGCT cis rs116095464 0.558 rs7356535 chr5:284117 G/T cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT trans rs804280 0.542 rs35647515 chr8:11791629 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Myopia (pathological); TGCT cis rs138857 0.515 rs9616375 chr22:50310600 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.22 -7.53 -0.56 9.3e-12 Mean platelet volume; TGCT cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.87 0.4 3.31e-6 Electroencephalogram traits; TGCT cis rs1552244 0.808 rs7615088 chr3:10035896 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs1322512 0.876 rs1744372 chr6:152944926 C/G cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs1552244 0.572 rs17032426 chr3:10167112 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs6725041 0.819 rs13429136 chr2:213092176 T/C cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs1903068 0.853 rs12498317 chr4:56007093 G/A cg09978860 chr4:56023921 NA 0.58 6.22 0.49 7.14e-9 Endometriosis; TGCT cis rs1878931 0.580 rs8062722 chr16:3409161 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.92 10.32 0.68 2.14e-18 Body mass index (adult); TGCT cis rs9811920 0.638 rs793471 chr3:99546335 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 6.82 0.52 3.63e-10 Axial length; TGCT cis rs11718455 0.960 rs17076254 chr3:44000361 C/T cg08738300 chr3:44038990 NA 0.81 6.09 0.48 1.31e-8 Coronary artery disease; TGCT trans rs12038357 0.867 rs10914965 chr1:34977219 A/G cg06277588 chr6:13489246 GFOD1 0.52 7.05 0.53 1.1e-10 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs2996428 0.667 rs72640928 chr1:3768568 T/C cg13057898 chr1:3703894 LRRC47 0.21 4.64 0.38 8.81e-6 Red cell distribution width; TGCT cis rs6911131 0.614 rs12202625 chr6:143880787 T/G cg26846959 chr6:143998958 PHACTR2 0.9 4.79 0.4 4.64e-6 Response to paliperidone in schizophrenia (positive Marder score); TGCT cis rs57590327 0.679 rs13061830 chr3:81525696 A/G cg07356753 chr3:81810745 GBE1 -0.53 -4.44 -0.37 1.97e-5 Extraversion; TGCT cis rs4665809 1.000 rs10048683 chr2:26320519 C/T cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg05785598 chr3:49045655 WDR6 0.37 4.87 0.4 3.34e-6 Menarche (age at onset); TGCT cis rs7772486 0.790 rs2814879 chr6:146201743 T/C cg23711669 chr6:146136114 FBXO30 0.93 10.56 0.69 5.35e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs9646954 0.542 rs4149505 chr2:101033697 G/A cg14675211 chr2:100938903 LONRF2 0.49 4.64 0.38 8.65e-6 Intelligence (multi-trait analysis); TGCT cis rs2562456 0.724 rs58001930 chr19:21742863 C/T cg25650185 chr19:21324782 ZNF431 -0.64 -5.73 -0.46 7.09e-8 Pain; TGCT cis rs9467711 0.720 rs3857546 chr6:26157762 C/T cg16898833 chr6:26189333 HIST1H4D 0.98 4.97 0.41 2.21e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9611519 0.780 rs9611542 chr22:41677317 C/T cg13695892 chr22:41940480 POLR3H -0.67 -6.47 -0.5 2.07e-9 Neuroticism; TGCT cis rs34779708 0.931 rs4351760 chr10:35280254 A/G cg04310649 chr10:35416472 CREM -0.51 -4.55 -0.38 1.24e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs9302065 0.565 rs2993585 chr13:95961966 G/A cg26751094 chr13:95954534 ABCC4 -0.4 -6.74 -0.52 5.33e-10 Blood metabolite levels; TGCT cis rs1218582 0.774 rs12036859 chr1:154859940 A/C cg09359103 chr1:154839909 KCNN3 0.7 14.57 0.79 1.23e-28 Prostate cancer; TGCT cis rs9467773 1.000 rs3736782 chr6:26505403 C/A cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs896854 0.902 rs896852 chr8:95960886 G/T cg09323728 chr8:95962352 TP53INP1 -0.53 -6.88 -0.53 2.67e-10 Type 2 diabetes; TGCT cis rs116095464 0.558 rs55664502 chr5:270485 T/C cg22857025 chr5:266934 NA -0.34 -6.64 -0.51 8.6e-10 Breast cancer; TGCT cis rs910316 0.712 rs175074 chr14:75504454 G/A cg08847533 chr14:75593920 NEK9 -0.82 -8.66 -0.61 2.07e-14 Height; TGCT cis rs8077577 0.895 rs11658477 chr17:18044893 G/A cg09161412 chr17:18057145 MYO15A -0.68 -5.24 -0.43 6.8e-7 Obesity-related traits; TGCT cis rs9660992 0.789 rs1768584 chr1:205240145 A/G cg00857998 chr1:205179979 DSTYK 0.51 4.71 0.39 6.47e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs7666738 0.830 rs7659006 chr4:98934529 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.841 rs115918392 chr4:119610356 T/A cg11846333 chr4:119757529 SEC24D 0.95 4.68 0.39 7.54e-6 Cannabis dependence symptom count; TGCT cis rs60154123 0.505 rs76426571 chr1:210041634 C/T cg12034118 chr1:209979487 IRF6 0.65 4.56 0.38 1.2e-5 Coronary artery disease; TGCT cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs12753569 0.748 rs1013629 chr1:76513759 A/G cg00791851 chr1:76518896 NA 0.34 4.58 0.38 1.13e-5 Personality dimensions; TGCT cis rs7666738 0.830 rs10009943 chr4:99021475 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4237845 0.788 rs1962047 chr12:58292707 G/A cg02175503 chr12:58329896 NA 0.52 4.86 0.4 3.52e-6 Intelligence (multi-trait analysis); TGCT cis rs7833790 0.632 rs6473308 chr8:82707708 G/A cg23324259 chr8:82754387 SNX16 -0.65 -5.05 -0.41 1.56e-6 Diastolic blood pressure; TGCT trans rs208520 0.526 rs6455072 chr6:66797215 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.1 -16.96 -0.84 4.22e-34 Exhaled nitric oxide output; TGCT cis rs6952809 0.926 rs55970742 chr7:2441337 C/T cg23289794 chr7:2394357 EIF3B -0.59 -4.92 -0.4 2.74e-6 Multiple sclerosis; TGCT cis rs9858542 0.953 rs6446264 chr3:49417243 C/A cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs5769765 0.955 rs2319465 chr22:50265784 A/C cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs6121246 0.542 rs6059761 chr20:30110522 G/C cg18721089 chr20:30220636 NA -0.54 -5.7 -0.46 8.21e-8 Mean corpuscular hemoglobin; TGCT cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg15320075 chr8:145703422 NA -0.73 -8.0 -0.58 7.69e-13 Age at first birth; TGCT cis rs4455778 0.580 rs35333419 chr7:49120543 A/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs79349575 0.745 rs170319 chr17:46991531 T/C cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs17376456 0.877 rs34673483 chr5:93315079 C/A cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs8077889 0.957 rs17742929 chr17:41891437 C/T cg26893861 chr17:41843967 DUSP3 1.04 11.89 0.73 3.25e-22 Triglycerides; TGCT cis rs6693567 0.565 rs11205355 chr1:150252329 G/A cg09579323 chr1:150459698 TARS2 -0.55 -5.13 -0.42 1.09e-6 Migraine; TGCT cis rs2066819 1.000 rs75598973 chr12:56746558 C/T cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs4888262 0.526 rs6564145 chr16:74621129 G/A cg01733217 chr16:74700730 RFWD3 0.74 7.4 0.55 1.83e-11 Testicular germ cell tumor; TGCT cis rs3015497 0.616 rs10131107 chr14:51062455 G/A cg04730355 chr14:51134070 SAV1 -0.64 -6.14 -0.48 1.01e-8 Mean platelet volume; TGCT cis rs12210905 1.000 rs9348756 chr6:27228259 G/A cg08851530 chr6:28072375 NA 1.37 5.96 0.47 2.46e-8 Hip circumference adjusted for BMI; TGCT cis rs9787249 0.957 rs3738673 chr1:40204823 C/T cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs651907 0.557 rs36002990 chr3:101437862 G/A cg12386194 chr3:101231763 SENP7 0.48 4.63 0.38 9.23e-6 Colorectal cancer; TGCT cis rs7208859 0.623 rs216434 chr17:28922335 G/C cg14008862 chr17:28927542 LRRC37B2 0.93 5.64 0.45 1.11e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3784262 0.867 rs8036453 chr15:58371635 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -6.98 -0.53 1.61e-10 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6912958 0.967 rs9450688 chr6:88159276 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.22 -0.49 7.06e-9 Monocyte percentage of white cells; TGCT cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg02725872 chr8:58115012 NA -0.39 -4.74 -0.39 5.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs954108 0.966 rs9508155 chr13:29372016 C/T cg11788234 chr13:29393811 NA 0.38 5.01 0.41 1.86e-6 Obesity-related traits; TGCT cis rs2688608 0.592 rs7908825 chr10:75554541 C/G cg04320760 chr10:75533139 FUT11 0.38 5.89 0.47 3.38e-8 Inflammatory bowel disease; TGCT cis rs2204008 0.550 rs11495600 chr12:38126654 C/T cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs4919669 0.720 rs729025 chr10:104342206 C/T cg05855489 chr10:104503620 C10orf26 0.71 4.69 0.39 7.18e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs826838 1.000 rs10880826 chr12:38672787 G/C cg26384229 chr12:38710491 ALG10B 1.05 10.25 0.68 3.18e-18 Heart rate; TGCT trans rs3780486 0.834 rs75443249 chr9:33149207 A/G cg04842962 chr6:43655489 MRPS18A 1.14 10.97 0.7 5.51e-20 IgG glycosylation; TGCT cis rs7914558 0.966 rs12569617 chr10:104729996 T/C cg04362960 chr10:104952993 NT5C2 0.59 5.3 0.43 5.09e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3087591 1.000 rs2940183 chr17:29416499 T/C cg24425628 chr17:29625626 OMG;NF1 0.49 7.33 0.55 2.61e-11 Hip circumference; TGCT cis rs9393692 0.905 rs7450556 chr6:26299900 C/T cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.13e-9 Educational attainment; TGCT cis rs9733 0.650 rs61820165 chr1:150555987 C/T cg13175981 chr1:150552382 MCL1 0.51 5.66 0.45 9.73e-8 Tonsillectomy; TGCT cis rs6121246 0.529 rs56153385 chr20:30187609 C/T cg21427119 chr20:30132790 HM13 -0.38 -5.63 -0.45 1.14e-7 Mean corpuscular hemoglobin; TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg01802117 chr1:53393560 SCP2 -0.41 -4.9 -0.4 2.96e-6 Monocyte count; TGCT trans rs2727020 0.615 rs4980435 chr11:49591576 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.48 -0.61 5.52e-14 Coronary artery disease; TGCT cis rs7647973 0.593 rs4855885 chr3:49690199 G/A cg05785598 chr3:49045655 WDR6 0.43 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs2997447 0.846 rs61775431 chr1:26411275 T/G cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs9926296 0.618 rs8058179 chr16:89846987 C/T cg03388025 chr16:89894329 SPIRE2 -0.38 -5.57 -0.45 1.5e-7 Vitiligo; TGCT cis rs1950626 0.833 rs2400963 chr14:101395706 A/G cg13660701 chr14:101034812 BEGAIN -0.45 -4.59 -0.38 1.07e-5 Pelvic organ prolapse (moderate/severe); TGCT cis rs6582630 0.555 rs6582503 chr12:38557886 A/C cg13010199 chr12:38710504 ALG10B 0.64 5.15 0.42 9.97e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.830 rs6823718 chr4:99063202 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6121246 0.567 rs6060263 chr20:30193110 T/C cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs4713118 0.662 rs9468274 chr6:28026077 G/T cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs6570726 0.599 rs4398765 chr6:145935006 C/A cg23711669 chr6:146136114 FBXO30 0.7 6.45 0.5 2.23e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs611744 0.967 rs603889 chr8:109224232 C/T cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT trans rs6089829 0.962 rs4809456 chr20:61660849 C/A cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs17712049 0.908 rs61102497 chr7:48198434 T/C cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs3766606 0.505 rs72633047 chr1:7935440 G/A cg26816564 chr1:7831052 VAMP3 0.65 4.98 0.41 2.11e-6 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; TGCT cis rs7017914 0.905 rs2639958 chr8:71922150 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs10832963 1.000 rs7943121 chr11:18656062 G/C cg09201001 chr11:18656081 SPTY2D1 1.04 11.77 0.73 6.2e-22 Breast cancer; TGCT cis rs896854 0.684 rs10099059 chr8:95986972 G/C cg13393036 chr8:95962371 TP53INP1 -0.58 -7.97 -0.58 8.83e-13 Type 2 diabetes; TGCT cis rs1552244 0.808 rs7615088 chr3:10035896 A/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs3858526 0.628 rs4237762 chr11:5956626 A/C cg02574844 chr11:5959923 NA -0.37 -4.51 -0.38 1.48e-5 DNA methylation (variation); TGCT cis rs2688608 0.592 rs10762559 chr10:75486453 G/C cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.41e-6 Inflammatory bowel disease; TGCT trans rs1005277 0.540 rs2474598 chr10:38430296 C/T cg17830980 chr10:43048298 ZNF37B 0.88 11.37 0.71 5.69e-21 Extrinsic epigenetic age acceleration; TGCT cis rs5760092 0.572 rs738806 chr22:24234172 A/G cg04234412 chr22:24373322 LOC391322 -0.57 -4.66 -0.39 8.18e-6 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs13256369 0.755 rs11776987 chr8:8559401 C/G cg18904891 chr8:8559673 CLDN23 0.56 5.0 0.41 1.94e-6 Obesity-related traits; TGCT cis rs7216064 1.000 rs62084240 chr17:65859233 C/A cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7666738 0.830 rs1593570 chr4:99017058 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3796352 1.000 rs11707780 chr3:53084326 A/G cg15956490 chr3:53032818 SFMBT1 -0.52 -6.19 -0.49 7.89e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg03762994 chr17:6899332 ALOX12 0.38 4.46 0.37 1.84e-5 Tonsillectomy; TGCT cis rs6582630 0.502 rs1915395 chr12:38420726 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.76 0.57 2.69e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs11779988 0.630 rs7821469 chr8:17894388 G/C cg01800426 chr8:17659068 MTUS1 -0.53 -4.5 -0.37 1.54e-5 Breast cancer; TGCT cis rs77106637 0.858 rs117819392 chr11:72514503 C/T cg03713592 chr11:72463424 ARAP1 0.95 6.2 0.49 7.69e-9 Type 2 diabetes; TGCT cis rs9486719 0.857 rs4346856 chr6:96880270 C/T cg06623918 chr6:96969491 KIAA0776 1.04 11.3 0.71 8.72e-21 Migraine;Coronary artery disease; TGCT cis rs3806843 0.576 rs246032 chr5:140332547 C/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6089829 0.926 rs7273917 chr20:61665975 G/A cg02380750 chr20:61661411 NA 0.34 6.03 0.48 1.72e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs6770219 0.516 rs55864811 chr3:186140901 G/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.46 0.37 1.81e-5 Cerebrospinal T-tau levels; TGCT cis rs4665809 0.549 rs3828255 chr2:26413252 G/A cg22920501 chr2:26401640 FAM59B 0.81 5.36 0.43 3.89e-7 Gut microbiome composition (summer); TGCT cis rs11122272 0.735 rs2295420 chr1:231485640 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.46e-11 Hemoglobin concentration; TGCT cis rs4378999 0.800 rs7615703 chr3:50732402 A/G cg09687332 chr3:49977370 RBM6 0.72 4.62 0.38 9.47e-6 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); TGCT cis rs3796352 1.000 rs750474 chr3:53085280 A/C cg15956490 chr3:53032818 SFMBT1 0.52 6.26 0.49 5.79e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs651907 0.557 rs13099674 chr3:101489629 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 11.22 0.71 1.34e-20 Colorectal cancer; TGCT cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs11209002 0.567 rs2224501 chr1:67532526 G/T cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs13096357 0.520 rs17080319 chr3:48732480 T/C cg00383909 chr3:49044727 WDR6 0.98 5.67 0.45 9.63e-8 Cognitive ability (multi-trait analysis); TGCT cis rs826838 0.967 rs7970069 chr12:38810631 T/C cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs33794 0.836 rs33782 chr3:45290954 G/T cg18645101 chr3:44551900 NA 0.54 4.74 0.39 5.75e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs4665809 0.590 rs35746418 chr2:26455002 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs6840360 0.571 rs11736116 chr4:152531816 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs7584330 0.910 rs66509917 chr2:238395394 T/G cg16989719 chr2:238392110 NA -0.27 -4.63 -0.38 8.95e-6 Prostate cancer; TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs11864453 0.826 rs12708928 chr16:72137227 C/A cg14768367 chr16:72042858 DHODH 0.48 4.44 0.37 1.98e-5 Fibrinogen levels; TGCT cis rs1868673 0.679 rs6778948 chr3:150134304 G/A cg24290546 chr3:150134309 TSC22D2 -0.25 -4.67 -0.39 7.66e-6 Waist circumference; TGCT cis rs13082711 0.954 rs34348584 chr3:27532704 T/C cg02860705 chr3:27208620 NA 0.34 4.77 0.39 5.18e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.44 -4.75 -0.39 5.47e-6 Blood metabolite levels; TGCT cis rs2228479 0.867 rs12919804 chr16:89945369 G/A cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs17376456 0.597 rs7708175 chr5:93381182 A/G cg21475434 chr5:93447410 FAM172A -0.61 -5.66 -0.45 1.01e-7 Diabetic retinopathy; TGCT cis rs7169223 0.653 rs1976007 chr15:79085023 T/C cg21242079 chr15:79101063 ADAMTS7 0.32 5.28 0.43 5.68e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs8084125 0.832 rs62105171 chr18:74945663 G/A cg05528293 chr18:74961138 GALR1 0.5 4.94 0.41 2.48e-6 Obesity-related traits; TGCT cis rs4713675 0.709 rs626156 chr6:33670482 A/G cg06471254 chr6:33690276 IP6K3 0.24 4.7 0.39 6.71e-6 Plateletcrit; TGCT cis rs1552244 1.000 rs9827740 chr3:10120531 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs308403 0.640 rs13128246 chr4:123721306 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.66 5.7 0.46 8.18e-8 Blood protein levels; TGCT cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.2 -0.42 7.9e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836974 0.681 rs8128827 chr21:40710547 C/T cg17971929 chr21:40555470 PSMG1 0.91 8.16 0.59 3.18e-13 Cognitive function; TGCT cis rs3125734 0.671 rs3852406 chr10:64015162 T/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.54 -0.38 1.31e-5 Rheumatoid arthritis; TGCT cis rs7044106 0.762 rs4142158 chr9:123410819 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.75 0.39 5.55e-6 Hip circumference adjusted for BMI; TGCT cis rs763121 0.853 rs926299 chr22:39095698 C/G cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT cis rs12908161 1.000 rs35808647 chr15:85377441 G/A cg11189052 chr15:85197271 WDR73 0.72 5.75 0.46 6.43e-8 Schizophrenia; TGCT cis rs933688 1.000 rs11948075 chr5:90680579 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.15 0.59 3.39e-13 Smoking behavior; TGCT cis rs11190604 0.767 rs12360395 chr10:102194074 A/T cg23241863 chr10:102295624 HIF1AN 0.65 4.89 0.4 3e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9818758 0.607 rs11716445 chr3:49406095 C/T cg00383909 chr3:49044727 WDR6 1.52 6.53 0.51 1.55e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs929596 0.728 rs6744284 chr2:234625297 C/T cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.31 -4.89 -0.4 3.1e-6 Total bilirubin levels in HIV-1 infection; TGCT cis rs727505 0.954 rs55768077 chr7:124663216 A/G cg23710748 chr7:124431027 NA -0.26 -4.54 -0.38 1.33e-5 Lewy body disease; TGCT cis rs12477438 0.539 rs720228 chr2:99704547 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.88 8.95 0.63 4.36e-15 Chronic sinus infection; TGCT cis rs13191362 1.000 rs73035012 chr6:162997279 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2153535 0.580 rs9328484 chr6:8524843 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9291683 0.546 rs13129453 chr4:10044784 T/C cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Bone mineral density; TGCT cis rs9814567 1.000 rs9863786 chr3:134247203 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs734999 0.549 rs6670198 chr1:2520527 T/C cg18854424 chr1:2615690 NA 0.49 5.72 0.46 7.65e-8 Ulcerative colitis; TGCT cis rs8177253 0.696 rs4459901 chr3:133465699 T/C cg08048268 chr3:133502702 NA -0.53 -6.97 -0.53 1.67e-10 Iron status biomarkers; TGCT cis rs11690935 0.549 rs62183819 chr2:172904520 G/T cg13550731 chr2:172543902 DYNC1I2 0.64 5.83 0.46 4.45e-8 Schizophrenia; TGCT cis rs6752107 0.901 rs10206299 chr2:234146271 G/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.87 0.4 3.36e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11098499 0.618 rs35265692 chr4:120325135 T/C cg09307838 chr4:120376055 NA 0.7 6.75 0.52 5.18e-10 Corneal astigmatism; TGCT cis rs587847 0.737 rs1520951 chr15:37668534 C/A cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs6598955 0.543 rs4585968 chr1:26535146 G/A cg04990556 chr1:26633338 UBXN11 0.81 7.32 0.55 2.76e-11 Obesity-related traits; TGCT cis rs10883723 0.962 rs1056739 chr10:104236542 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 7.52 0.56 9.74e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs3784262 0.631 rs12903724 chr15:58310387 G/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.83e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs75059851 0.756 rs11223647 chr11:133839588 G/A cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs4711350 0.734 rs9380379 chr6:33766131 A/G cg18005901 chr6:33739558 LEMD2 -0.55 -6.19 -0.49 8.02e-9 Schizophrenia; TGCT cis rs7772486 0.790 rs2265469 chr6:146219049 T/C cg23711669 chr6:146136114 FBXO30 0.89 10.16 0.67 5.28e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs514406 0.861 rs2477741 chr1:53265278 A/G cg08736216 chr1:53307985 ZYG11A 0.25 4.86 0.4 3.55e-6 Monocyte count; TGCT cis rs10782582 0.593 rs77733234 chr1:76101655 A/T cg10523679 chr1:76189770 ACADM -0.68 -7.45 -0.56 1.4e-11 Daytime sleep phenotypes; TGCT cis rs6809651 0.524 rs1356292 chr3:185824903 C/T cg00760338 chr3:185826511 ETV5 0.78 6.52 0.51 1.56e-9 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs10489525 0.599 rs34710929 chr1:115606608 G/A cg12756093 chr1:115239321 AMPD1 -0.4 -5.49 -0.44 2.19e-7 Autism; TGCT cis rs7760949 0.963 rs9396248 chr6:13906360 A/G cg27413430 chr6:13925136 RNF182 0.52 4.78 0.39 4.9e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs4680 0.701 rs4646317 chr22:19952168 G/A cg22546130 chr22:19950026 COMT -0.32 -4.67 -0.39 7.58e-6 Blood metabolite levels; TGCT cis rs6723226 1.000 rs6723226 chr2:32849207 C/T cg02381751 chr2:32503542 YIPF4 0.49 4.7 0.39 6.86e-6 Intelligence (multi-trait analysis); TGCT cis rs11148252 0.532 rs9536190 chr13:53181044 T/C cg02158880 chr13:53174818 NA 0.5 5.91 0.47 3.07e-8 Lewy body disease; TGCT cis rs4654899 0.861 rs10916876 chr1:21169996 T/C cg01072550 chr1:21505969 NA 0.48 7.58 0.56 7.09e-12 Superior frontal gyrus grey matter volume; TGCT cis rs10242455 0.702 rs75156180 chr7:98964100 G/A cg13560068 chr7:99070416 ZNF789 1.09 4.66 0.39 8.13e-6 Blood metabolite levels; TGCT cis rs938554 0.571 rs4144 chr4:10016322 T/C cg00071950 chr4:10020882 SLC2A9 0.55 4.78 0.39 4.88e-6 Blood metabolite levels; TGCT cis rs1857353 1.000 rs17096888 chr1:75903999 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7119038 0.731 rs10892283 chr11:118636980 A/G cg19308663 chr11:118741387 NA 0.3 5.59 0.45 1.37e-7 Sjögren's syndrome; TGCT cis rs10791097 0.694 rs2155751 chr11:130755240 G/A cg05962950 chr11:130786565 SNX19 0.91 11.68 0.72 1.01e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1799949 1.000 rs11659028 chr17:41195025 T/A cg23758822 chr17:41437982 NA 0.74 6.78 0.52 4.27e-10 Menopause (age at onset); TGCT cis rs1372520 0.564 rs2737011 chr4:90746219 T/C cg15133208 chr4:90757351 SNCA -0.5 -5.81 -0.46 4.96e-8 Neuroticism; TGCT cis rs4319547 0.626 rs11057882 chr12:122875046 A/G cg08088222 chr12:122070432 ORAI1 0.25 4.49 0.37 1.58e-5 Body mass index; TGCT trans rs114540395 0.858 rs3730478 chr10:103339142 G/A cg10198749 chr1:39920707 MACF1 0.55 7.06 0.54 1.06e-10 Schizophrenia; TGCT cis rs6121246 0.909 rs6060812 chr20:30292803 C/T cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs12477438 0.501 rs11683107 chr2:99759235 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.28 0.68 2.66e-18 Chronic sinus infection; TGCT cis rs68170813 0.523 rs10253172 chr7:106786474 C/T cg02696742 chr7:106810147 HBP1 0.74 6.15 0.48 9.79e-9 Coronary artery disease; TGCT cis rs7666738 0.830 rs11735193 chr4:98761900 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.679 rs72649119 chr8:58040301 T/C cg08280861 chr8:58055591 NA 0.35 4.92 0.4 2.72e-6 Developmental language disorder (linguistic errors); TGCT cis rs10426930 0.639 rs1136405 chr19:5062814 T/C cg09001777 chr19:5851504 FUT3 -0.22 -4.77 -0.39 4.98e-6 Monocyte percentage of white cells; TGCT cis rs10488031 0.557 rs74336212 chr7:37082618 A/G cg06458904 chr7:36312573 EEPD1 0.56 4.7 0.39 6.79e-6 QT interval; TGCT trans rs2469997 1.000 rs2957356 chr8:120373995 T/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs35235971 chr4:98999833 G/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9467711 0.606 rs2076030 chr6:26426856 G/A cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg22920501 chr2:26401640 FAM59B -0.8 -6.34 -0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs9733 0.596 rs7418501 chr1:150711896 A/T cg09365446 chr1:150670422 GOLPH3L 0.29 4.45 0.37 1.86e-5 Tonsillectomy; TGCT cis rs17376456 0.877 rs114256265 chr5:93473130 T/A cg25358565 chr5:93447407 FAM172A 0.92 8.23 0.59 2.17e-13 Diabetic retinopathy; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg02073558 chr3:44770973 ZNF501 0.66 6.66 0.51 7.99e-10 Depressive symptoms; TGCT cis rs6429082 0.818 rs834198 chr1:235671987 A/G cg26050004 chr1:235667680 B3GALNT2 0.58 5.16 0.42 9.46e-7 Adiposity; TGCT cis rs6543140 0.929 rs7602207 chr2:103032366 C/G cg09003973 chr2:102972529 NA 0.59 4.95 0.41 2.39e-6 Blood protein levels; TGCT cis rs4704846 0.861 rs4704849 chr5:156532928 A/G cg12943317 chr5:156479607 HAVCR1 -0.34 -4.7 -0.39 6.82e-6 Blood protein levels; TGCT cis rs12725198 0.507 rs41393951 chr1:16053493 C/T cg02485345 chr1:16061554 SLC25A34 0.39 4.64 0.38 8.66e-6 Cardiac Troponin-T levels; TGCT cis rs9513593 1.000 rs4772181 chr13:99860966 C/G cg21788972 chr13:99853209 UBAC2 0.61 4.93 0.4 2.59e-6 Psoriasis; TGCT cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT trans rs9313296 0.661 rs10059799 chr5:165556009 A/G cg25743221 chr6:152501416 SYNE1 0.84 7.1 0.54 8.6e-11 Weight;Waist circumference; TGCT cis rs11148252 0.875 rs9526913 chr13:52975837 T/C cg00495681 chr13:53174319 NA 0.48 4.44 0.37 1.94e-5 Lewy body disease; TGCT cis rs36051895 0.658 rs10975029 chr9:5251068 T/C cg02405213 chr9:5042618 JAK2 -0.7 -8.61 -0.61 2.76e-14 Pediatric autoimmune diseases; TGCT cis rs12762955 0.561 rs7076107 chr10:1043647 T/C cg18964960 chr10:1102726 WDR37 -0.68 -5.99 -0.47 2.07e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs13177918 0.603 rs13175992 chr5:149830589 G/A cg14059543 chr5:149831962 NA -0.68 -9.13 -0.63 1.6e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg25767906 chr1:53392781 SCP2 -0.49 -5.73 -0.46 7.08e-8 Monocyte count; TGCT cis rs6089584 0.706 rs6089625 chr20:60620622 T/C cg13770153 chr20:60521292 NA -0.54 -7.12 -0.54 7.73e-11 Body mass index; TGCT cis rs2235642 1.000 rs2076438 chr16:1584618 T/C cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.81 -0.46 5.02e-8 Coronary artery disease; TGCT cis rs7568458 0.905 rs17026396 chr2:85759127 C/T cg17127132 chr2:85788382 GGCX -0.72 -6.7 -0.52 6.53e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs72781680 0.821 rs55948613 chr2:24094787 A/G cg08917208 chr2:24149416 ATAD2B 0.75 4.68 0.39 7.44e-6 Lymphocyte counts; TGCT cis rs8031584 0.958 rs34294266 chr15:31246840 A/G cg08704250 chr15:31115839 NA -0.36 -4.97 -0.41 2.2e-6 Huntington's disease progression; TGCT cis rs12510870 0.544 rs34238679 chr4:74387770 T/A cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs1018836 0.828 rs7008172 chr8:91551613 C/T cg16814680 chr8:91681699 NA -0.72 -7.53 -0.56 8.91e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT trans rs1814175 0.781 rs12286395 chr11:49954062 C/G cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs13256369 1.000 rs4840352 chr8:8573508 A/G cg06671706 chr8:8559999 CLDN23 0.34 4.44 0.37 1.99e-5 Obesity-related traits; TGCT cis rs7312933 0.558 rs4768402 chr12:42755576 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.72 -0.46 7.52e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6840360 0.571 rs718801 chr4:152549247 C/T cg17479576 chr4:152424074 FAM160A1 -0.72 -7.81 -0.57 2.05e-12 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.516 rs9379818 chr6:26023206 G/T cg17042849 chr6:26104293 HIST1H4C -0.66 -5.89 -0.47 3.32e-8 Height; TGCT cis rs1903068 0.657 rs41408948 chr4:55992025 G/A cg16572876 chr4:56024045 NA 0.42 4.43 0.37 2.01e-5 Endometriosis; TGCT cis rs611744 0.967 rs584555 chr8:109218612 C/G cg21045802 chr8:109455806 TTC35 0.5 4.56 0.38 1.23e-5 Dupuytren's disease; TGCT cis rs909674 0.818 rs5750830 chr22:39840828 C/A cg01416388 chr22:39784598 NA -0.69 -6.27 -0.49 5.6e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2836974 0.897 rs1984022 chr21:40596085 G/A cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.67e-16 Cognitive function; TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg17775962 chr7:1200435 ZFAND2A 0.27 4.61 0.38 9.85e-6 Longevity;Endometriosis; TGCT cis rs17345786 0.798 rs1609159 chr3:101275902 A/C cg12386194 chr3:101231763 SENP7 0.57 5.45 0.44 2.62e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 1.000 rs2424700 chr20:25266513 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17534004 1.000 rs35646895 chr13:31469604 C/T cg13251181 chr13:31481184 C13orf33 0.37 4.6 0.38 1.04e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg10802521 chr3:52805072 NEK4 -0.73 -9.23 -0.64 9.18e-16 Bipolar disorder; TGCT cis rs7918232 0.941 rs788210 chr10:27476948 T/C cg14442939 chr10:27389572 ANKRD26 -0.82 -5.75 -0.46 6.69e-8 Breast cancer; TGCT cis rs116095464 0.558 rs10057492 chr5:239503 T/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs9790314 0.846 rs7652267 chr3:160998497 A/G cg03342759 chr3:160939853 NMD3 -0.53 -6.02 -0.48 1.82e-8 Morning vs. evening chronotype; TGCT cis rs9467603 1.000 rs9467607 chr6:25809477 G/A cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs908922 0.573 rs7544564 chr1:152527007 A/C cg20991723 chr1:152506922 NA 0.44 5.96 0.47 2.44e-8 Hair morphology; TGCT cis rs2933343 0.953 rs2933344 chr3:128658715 A/G cg11901034 chr3:128598214 ACAD9 -0.59 -4.65 -0.39 8.49e-6 IgG glycosylation; TGCT trans rs17684571 0.938 rs4074102 chr6:56562295 C/T cg14229071 chr15:89282588 NA 0.52 6.82 0.52 3.54e-10 Schizophrenia; TGCT cis rs6700896 0.500 rs72641129 chr1:66075123 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.64 4.95 0.41 2.41e-6 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4319547 0.915 rs7314638 chr12:122983460 A/G cg23029597 chr12:123009494 RSRC2 -0.29 -4.87 -0.4 3.34e-6 Body mass index; TGCT cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs597539 0.652 rs513615 chr11:68705504 G/T cg04772025 chr11:68637568 NA 0.62 6.81 0.52 3.77e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2295359 1.000 rs4655682 chr1:67610967 C/T cg12940439 chr1:67600707 NA 0.58 6.1 0.48 1.24e-8 Psoriasis; TGCT cis rs9311474 0.508 rs11714565 chr3:52606292 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs2243480 0.666 rs1880311 chr7:65276752 G/C cg18252515 chr7:66147081 NA 1.1 5.88 0.47 3.55e-8 Diabetic kidney disease; TGCT cis rs2153535 0.601 rs4140585 chr6:8503298 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4711350 0.954 rs943464 chr6:33731469 A/G cg18005901 chr6:33739558 LEMD2 0.57 5.75 0.46 6.52e-8 Schizophrenia; TGCT cis rs853679 0.567 rs13196606 chr6:28370078 C/T cg18815343 chr6:28367644 ZSCAN12 -0.52 -4.67 -0.39 7.85e-6 Depression; TGCT cis rs13191362 1.000 rs13210412 chr6:163019478 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs13242816 1.000 rs3779513 chr7:116178992 T/C cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs2295359 0.892 rs10889657 chr1:67615487 A/G cg08029281 chr1:67600428 NA 0.4 4.55 0.38 1.28e-5 Psoriasis; TGCT cis rs2832191 0.935 rs11910475 chr21:30519702 T/C cg24692254 chr21:30365293 RNF160 -0.77 -7.9 -0.58 1.28e-12 Dental caries; TGCT cis rs9928842 0.771 rs4888363 chr16:75277344 A/T cg09066997 chr16:75300724 BCAR1 0.25 4.72 0.39 6.17e-6 Alcoholic chronic pancreatitis; TGCT cis rs8031584 0.678 rs8028173 chr15:31155749 A/G cg08704250 chr15:31115839 NA -0.43 -6.31 -0.49 4.47e-9 Huntington's disease progression; TGCT cis rs7843479 0.965 rs4636204 chr8:21823206 T/G cg17168535 chr8:21777572 XPO7 0.64 5.91 0.47 3.12e-8 Mean corpuscular volume; TGCT cis rs7169223 0.653 rs1994017 chr15:79080306 T/C cg03762349 chr15:79060523 ADAMTS7 -0.24 -5.02 -0.41 1.77e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs3096299 0.685 rs4785676 chr16:89553624 T/C cg08392591 chr16:89556376 ANKRD11 0.55 5.1 0.42 1.25e-6 Multiple myeloma (IgH translocation); TGCT cis rs1670533 1.000 rs2045068 chr4:1052212 G/A cg20887711 chr4:1340912 KIAA1530 0.73 5.74 0.46 6.77e-8 Recombination rate (females); TGCT cis rs12935418 0.616 rs12444054 chr16:80964217 T/G cg07676361 chr16:80966860 NA -0.35 -4.64 -0.38 8.56e-6 Mean corpuscular volume; TGCT cis rs4722166 1.000 rs4722166 chr7:22738762 G/T cg26061582 chr7:22766209 IL6 0.39 4.65 0.39 8.32e-6 Lung cancer; TGCT cis rs9914988 0.778 rs35398767 chr17:27122960 A/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs713587 0.691 rs754537 chr2:25176277 A/T cg15423357 chr2:25149977 NA -0.46 -4.52 -0.38 1.41e-5 Body mass index in non-asthmatics; TGCT cis rs2153535 0.601 rs330105 chr6:8543981 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.63 0.45 1.14e-7 Motion sickness; TGCT cis rs1451375 0.669 rs59086818 chr7:50653830 G/A cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs2046867 0.818 rs6792109 chr3:72867091 C/T cg25664220 chr3:72788482 NA -0.54 -7.03 -0.53 1.22e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs651907 0.535 rs13094753 chr3:101525082 A/G cg12386194 chr3:101231763 SENP7 0.47 4.7 0.39 6.87e-6 Colorectal cancer; TGCT cis rs2721195 0.845 rs2721150 chr8:145724973 C/G cg11211951 chr8:145729740 GPT 0.27 6.24 0.49 6.37e-9 Age at first birth; TGCT cis rs8038465 1.000 rs8032727 chr15:73977336 A/G cg15420318 chr15:73925796 NPTN 0.7 6.55 0.51 1.37e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1008375 0.931 rs3775926 chr4:17599837 G/A cg10189774 chr4:17578691 LAP3 0.69 6.07 0.48 1.47e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1005277 0.579 rs176880 chr10:38401417 C/G cg27523141 chr10:43048294 ZNF37B -0.74 -8.46 -0.6 6.33e-14 Extrinsic epigenetic age acceleration; TGCT cis rs7267979 0.966 rs6037097 chr20:25347221 C/T cg16686733 chr20:25566563 NINL 0.58 5.78 0.46 5.62e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4468007 0.505 rs4837905 chr9:124620796 C/T cg01549227 chr9:124980074 LHX6 -0.3 -4.55 -0.38 1.24e-5 Educational attainment; TGCT cis rs35146811 0.735 rs858506 chr7:99820050 T/C cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs911555 0.962 rs2765042 chr14:103990745 G/A cg12935359 chr14:103987150 CKB 0.38 5.37 0.43 3.7e-7 Intelligence (multi-trait analysis); TGCT cis rs597539 0.617 rs669659 chr11:68635623 G/C cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11627546 0.615 rs4528503 chr14:70366437 A/G cg10496350 chr14:71275911 MAP3K9 -0.89 -4.5 -0.37 1.52e-5 Red blood cell traits; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT trans rs2688608 0.725 rs2688623 chr10:75689615 C/T cg13918328 chr10:52500089 ASAH2B 0.66 6.71 0.52 6.1e-10 Inflammatory bowel disease; TGCT cis rs950776 0.518 rs4887062 chr15:78837801 G/A cg06917634 chr15:78832804 PSMA4 -0.93 -9.06 -0.63 2.33e-15 Sudden cardiac arrest; TGCT cis rs4601821 1.000 rs877138 chr11:113256508 A/G cg14159747 chr11:113255604 NA -0.37 -4.44 -0.37 1.97e-5 Alcoholic chronic pancreatitis; TGCT cis rs929596 0.697 rs17863787 chr2:234611094 T/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.29 -4.49 -0.37 1.63e-5 Total bilirubin levels in HIV-1 infection; TGCT cis rs5769765 0.908 rs2319464 chr22:50265777 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs9302065 0.565 rs2992908 chr13:95960600 G/A cg24476569 chr13:95954382 ABCC4 -0.54 -8.26 -0.6 1.9e-13 Blood metabolite levels; TGCT cis rs36051895 0.664 rs28378223 chr9:5113087 C/G cg02405213 chr9:5042618 JAK2 -0.75 -10.29 -0.68 2.5e-18 Pediatric autoimmune diseases; TGCT cis rs10910092 1 rs10910092 chr1:2501516 A/G cg18854424 chr1:2615690 NA 0.45 5.38 0.43 3.62e-7 Ulcerative colitis; TGCT cis rs910316 1.000 rs4903289 chr14:75623988 C/T cg11812906 chr14:75593930 NEK9 -0.74 -7.21 -0.54 4.75e-11 Height; TGCT cis rs801193 0.967 rs2707849 chr7:66152712 T/C cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs4654899 1.000 rs6700718 chr1:21299363 A/C cg01072550 chr1:21505969 NA 0.51 8.15 0.59 3.28e-13 Superior frontal gyrus grey matter volume; TGCT cis rs7216064 1.000 rs55939964 chr17:65869297 G/A cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7772486 0.790 rs2253880 chr6:146200774 T/C cg23711669 chr6:146136114 FBXO30 0.93 10.56 0.69 5.35e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg18252515 chr7:66147081 NA -1.1 -7.18 -0.54 5.77e-11 Diabetic kidney disease; TGCT cis rs6840360 0.615 rs4696290 chr4:152631472 A/G cg22705602 chr4:152727874 NA -0.34 -5.83 -0.46 4.4e-8 Intelligence (multi-trait analysis); TGCT trans rs1496653 0.602 rs36021750 chr3:23609741 C/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.57 5.14 0.42 1.03e-6 Height; TGCT cis rs13082711 0.911 rs11717669 chr3:27458484 C/T cg02860705 chr3:27208620 NA 0.35 4.83 0.4 3.9e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs734999 0.545 rs6698817 chr1:2564183 T/C cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs73110464 0.562 rs2363634 chr12:53354683 A/G cg16329197 chr12:53359506 NA -0.56 -7.66 -0.57 4.65e-12 Cancer (pleiotropy); TGCT cis rs7568458 0.837 rs3731827 chr2:85806068 T/C cg17127132 chr2:85788382 GGCX 0.72 6.68 0.51 7.18e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs17068510 0.572 rs11779756 chr8:3883321 C/T cg25338036 chr8:3047536 CSMD1 -0.44 -4.57 -0.38 1.18e-5 Cerebrospinal fluid clusterin levels; TGCT cis rs9583531 0.714 rs76166228 chr13:111343774 T/C cg15747390 chr13:111297551 CARS2 0.86 5.84 0.46 4.21e-8 Coronary artery disease; TGCT cis rs36051895 0.632 rs7047795 chr9:5181467 C/T cg02405213 chr9:5042618 JAK2 -0.74 -10.38 -0.68 1.47e-18 Pediatric autoimmune diseases; TGCT cis rs79349575 0.783 rs62075839 chr17:46996434 G/C cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs62064224 0.902 rs35830939 chr17:30627564 A/C cg09324608 chr17:30823087 MYO1D 0.21 4.47 0.37 1.73e-5 Schizophrenia; TGCT cis rs2153535 0.580 rs4451187 chr6:8473910 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.7 0.46 8.28e-8 Motion sickness; TGCT cis rs929354 0.772 rs6957939 chr7:156978485 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs1568889 0.775 rs35243076 chr11:28250618 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 10.85 0.7 1.1e-19 Bipolar disorder; TGCT cis rs7772486 0.692 rs2265915 chr6:146194332 A/T cg13319975 chr6:146136371 FBXO30 -0.54 -4.81 -0.4 4.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs72781680 1.000 rs12616899 chr2:24165235 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs1801251 0.964 rs13007783 chr2:233566679 G/A cg08000102 chr2:233561755 GIGYF2 0.64 6.44 0.5 2.36e-9 Coronary artery disease; TGCT cis rs7829975 0.628 rs1109618 chr8:8571364 A/T cg06636001 chr8:8085503 FLJ10661 -0.61 -5.26 -0.43 6e-7 Mood instability; TGCT cis rs2692947 0.644 rs772178 chr2:96963684 C/T cg23100626 chr2:96804247 ASTL -0.45 -5.64 -0.45 1.08e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7937682 0.889 rs490199 chr11:111487890 A/G cg09085632 chr11:111637200 PPP2R1B -1.1 -11.94 -0.73 2.41e-22 Primary sclerosing cholangitis; TGCT cis rs35146811 0.659 rs863450 chr7:99821685 C/T cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs3806843 0.576 rs246030 chr5:140333154 C/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs992157 0.644 rs6741757 chr2:219182748 T/C cg00012203 chr2:219082015 ARPC2 0.71 6.71 0.52 6.34e-10 Colorectal cancer; TGCT cis rs858239 0.539 rs4365988 chr7:23190871 T/C cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7617773 0.817 rs11720622 chr3:48246679 G/A cg11946769 chr3:48343235 NME6 0.74 7.01 0.53 1.38e-10 Coronary artery disease; TGCT cis rs425277 0.959 rs77665022 chr1:2065958 C/T cg24578937 chr1:2090814 PRKCZ 0.33 7.85 0.58 1.71e-12 Height; TGCT cis rs7312933 0.558 rs4768411 chr12:42855390 A/G cg19980929 chr12:42632907 YAF2 -0.4 -5.75 -0.46 6.7e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7959452 0.590 rs10878974 chr12:69781528 C/G cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs1865760 0.623 rs12216125 chr6:25997458 C/T cg16482183 chr6:26056742 HIST1H1C 0.63 5.49 0.44 2.15e-7 Height; TGCT cis rs7666738 0.791 rs13128640 chr4:99003918 A/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7246657 1.000 rs6508710 chr19:37749886 A/G cg18154014 chr19:37997991 ZNF793 0.68 4.69 0.39 6.97e-6 Coronary artery calcification; TGCT cis rs7104764 1.000 rs10400248 chr11:247029 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs9902453 0.967 rs9900911 chr17:28330280 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs1865760 0.566 rs2051544 chr6:26071093 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.79 7.55 0.56 8.02e-12 Height; TGCT cis rs72845660 0.550 rs6584499 chr10:104188259 A/C cg26089160 chr10:104170217 PSD 0.46 4.51 0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg08280861 chr8:58055591 NA 0.39 4.81 0.4 4.3e-6 Developmental language disorder (linguistic errors); TGCT cis rs9457247 1.000 rs402749 chr6:167386104 C/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs710216 0.917 rs900836 chr1:43412727 T/C cg03128534 chr1:43423976 SLC2A1 -0.56 -4.53 -0.38 1.35e-5 Red cell distribution width; TGCT cis rs7666738 0.830 rs6833312 chr4:98951356 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7611238 0.560 rs1994880 chr3:195140478 C/T cg27323046 chr3:195102265 ACAP2 0.38 5.13 0.42 1.09e-6 Body mass index; TGCT cis rs4132509 0.739 rs79367267 chr1:243689543 C/A cg21452805 chr1:244014465 NA 0.75 4.55 0.38 1.28e-5 RR interval (heart rate); TGCT cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg23708337 chr7:1209742 NA 0.56 5.08 0.42 1.34e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9921192 0.934 rs233948 chr16:4327174 C/T cg00021532 chr16:4324280 TFAP4 0.83 9.35 0.64 4.7e-16 Prostate-specific antigen levels; TGCT cis rs4299518 0.516 rs12490293 chr3:45788127 T/C cg04837898 chr3:45731254 SACM1L 0.48 4.86 0.4 3.41e-6 Hirschsprung disease; TGCT cis rs9814567 0.752 rs4456908 chr3:134340353 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.72 -6.5 -0.5 1.78e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2486288 0.656 rs8039352 chr15:45551790 A/G cg26924012 chr15:45694286 SPATA5L1 -0.79 -8.16 -0.59 3.27e-13 Glomerular filtration rate; TGCT cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs13191362 1.000 rs36042757 chr6:163004744 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs35883536 0.626 rs34752753 chr1:101045193 T/G cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs9486719 1.000 rs12190397 chr6:97036465 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs208520 0.608 rs3846803 chr6:66805743 C/A cg07460842 chr6:66804631 NA -0.94 -9.83 -0.66 3.3e-17 Exhaled nitric oxide output; TGCT cis rs1577917 0.740 rs2758843 chr6:86328431 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.54 -4.87 -0.4 3.28e-6 Response to antipsychotic treatment; TGCT cis rs1008375 0.966 rs6832387 chr4:17697546 G/T cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7552404 0.960 rs4949877 chr1:76201668 C/G cg22875332 chr1:76189707 ACADM 0.77 9.42 0.65 3.17e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs112591243 0.685 rs78463142 chr21:47964481 A/G cg10657630 chr21:48055338 PRMT2 1.03 4.64 0.38 8.57e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9393692 0.846 rs9366651 chr6:26336696 G/T cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.08e-7 Educational attainment; TGCT cis rs7178572 0.539 rs12594346 chr15:77671966 A/T cg22256960 chr15:77711686 NA 0.82 8.1 0.59 4.32e-13 Type 2 diabetes; TGCT cis rs3749237 0.615 rs6792911 chr3:49429856 C/T cg07636037 chr3:49044803 WDR6 0.64 6.12 0.48 1.11e-8 Resting heart rate; TGCT cis rs4273100 0.790 rs60606605 chr17:19277144 G/A cg01534423 chr17:18965556 NA 0.95 6.45 0.5 2.28e-9 Schizophrenia; TGCT cis rs12579753 0.879 rs11115007 chr12:82164673 A/T cg21231944 chr12:82153410 PPFIA2 -0.34 -4.61 -0.38 9.77e-6 Resting heart rate; TGCT cis rs6450176 0.625 rs35027270 chr5:53289068 T/C ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.58 -0.45 1.45e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs17030434 0.954 rs10000558 chr4:154766835 A/T cg14289246 chr4:154710475 SFRP2 -0.95 -7.71 -0.57 3.61e-12 Electrocardiographic conduction measures; TGCT cis rs3008870 1.000 rs2815371 chr1:67504313 A/G cg03991309 chr1:68237761 GNG12 0.27 4.6 0.38 1.02e-5 Lymphocyte percentage of white cells; TGCT cis rs12681288 0.823 rs2600518 chr8:1007214 A/T cg04851639 chr8:1020857 NA -0.36 -6.34 -0.49 3.93e-9 Schizophrenia; TGCT cis rs6500602 0.634 rs2270365 chr16:4526758 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.28 5.17 0.42 9.05e-7 Schizophrenia; TGCT cis rs2299587 0.554 rs2283106 chr8:17754330 G/A cg01800426 chr8:17659068 MTUS1 -0.57 -5.11 -0.42 1.21e-6 Economic and political preferences; TGCT cis rs7582180 0.663 rs2309800 chr2:100992086 C/T cg08017756 chr2:100939284 LONRF2 -0.31 -4.99 -0.41 2.01e-6 Intelligence (multi-trait analysis); TGCT cis rs7312774 0.618 rs4964513 chr12:107375758 T/C cg16260113 chr12:107380972 MTERFD3 1.04 5.25 0.43 6.37e-7 Severe influenza A (H1N1) infection; TGCT cis rs9372253 0.678 rs6568644 chr6:110707820 C/T cg19196401 chr6:110721138 DDO -0.42 -5.67 -0.45 9.33e-8 Platelet distribution width; TGCT cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg02725872 chr8:58115012 NA -0.39 -4.74 -0.39 5.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs7552404 0.883 rs77773255 chr1:76217193 G/A cg22875332 chr1:76189707 ACADM 0.77 9.42 0.65 3.17e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs9894429 1.000 rs9748176 chr17:79584043 C/G cg21984481 chr17:79567631 NPLOC4 -0.24 -4.5 -0.37 1.57e-5 Eye color traits; TGCT cis rs735396 0.595 rs1169279 chr12:121455873 C/T cg15155738 chr12:121454335 C12orf43 0.6 5.47 0.44 2.43e-7 N-glycan levels; TGCT cis rs7552404 1.000 rs11161511 chr1:76210477 A/G cg22875332 chr1:76189707 ACADM -0.73 -8.82 -0.62 8.63e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9341808 0.628 rs9294172 chr6:80918561 G/A cg08355045 chr6:80787529 NA 0.31 5.17 0.42 9e-7 Sitting height ratio; TGCT cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs2204008 0.774 rs9669565 chr12:38294428 C/A cg26384229 chr12:38710491 ALG10B 0.8 7.04 0.53 1.17e-10 Bladder cancer; TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg18402987 chr7:1209562 NA 0.4 5.07 0.41 1.42e-6 Longevity;Endometriosis; TGCT cis rs6032067 0.516 rs991049 chr20:43898139 C/T cg16667508 chr20:43936853 MATN4;RBPJL 0.37 6.01 0.47 1.92e-8 Blood protein levels; TGCT cis rs6547741 0.844 rs7382 chr2:27873415 G/A cg27432699 chr2:27873401 GPN1 -0.24 -6.05 -0.48 1.61e-8 Oral cavity cancer; TGCT cis rs77372450 0.551 rs73814843 chr5:157063058 A/C cg19063654 chr5:156516798 HAVCR2 -0.37 -4.43 -0.37 2.01e-5 Bipolar disorder (body mass index interaction); TGCT cis rs13191362 0.507 rs2849540 chr6:163094522 G/A cg21926612 chr6:163149169 PACRG;PARK2 -0.66 -5.88 -0.47 3.61e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3733585 0.673 rs7375587 chr4:9954758 A/T cg11266682 chr4:10021025 SLC2A9 0.55 7.09 0.54 8.77e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6089584 0.854 rs8117075 chr20:60613766 T/C cg06108461 chr20:60628389 TAF4 -0.69 -10.56 -0.69 5.46e-19 Body mass index; TGCT cis rs7267979 1.000 rs6050598 chr20:25397257 C/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs736408 0.812 rs2270197 chr3:52824095 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.51 4.9 0.4 2.89e-6 Bipolar disorder; TGCT cis rs7731657 0.537 rs10062336 chr5:130193668 T/A cg08523029 chr5:130500466 HINT1 -0.55 -4.57 -0.38 1.15e-5 Fasting plasma glucose; TGCT cis rs6921919 0.583 rs7749736 chr6:28346031 G/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1577917 0.771 rs10944133 chr6:86358984 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs3764400 0.567 rs12946143 chr17:46154943 C/T cg02340556 chr17:46797764 NA 0.41 4.47 0.37 1.72e-5 Body mass index; TGCT cis rs17253792 0.822 rs17832365 chr14:56153531 C/G cg01858014 chr14:56050164 KTN1 -0.37 -4.83 -0.4 4e-6 Putamen volume; TGCT cis rs877282 0.853 rs10904545 chr10:757100 G/A cg17470449 chr10:769945 NA 0.35 5.06 0.41 1.44e-6 Uric acid levels; TGCT cis rs11105298 0.891 rs4842661 chr12:89930399 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.08 -0.42 1.35e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4891159 0.730 rs7236220 chr18:74099350 A/G cg24786174 chr18:74118243 ZNF516 -0.59 -9.27 -0.64 7.37e-16 Longevity; TGCT cis rs875971 1.000 rs2420820 chr7:66091907 T/C cg18876405 chr7:65276391 NA -0.33 -5.05 -0.41 1.52e-6 Aortic root size; TGCT cis rs9916302 0.904 rs9904334 chr17:37468336 G/A cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs6088580 0.634 rs9789792 chr20:32957709 G/A cg08999081 chr20:33150536 PIGU -0.26 -4.98 -0.41 2.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs9303401 0.615 rs7502342 chr17:56922629 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs12048904 1.000 rs12048904 chr1:101331536 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.54 -5.07 -0.41 1.43e-6 Multiple sclerosis; TGCT cis rs10779751 1.000 rs1205592 chr1:11305663 C/T cg08854313 chr1:11322531 MTOR 1.0 9.28 0.64 7.14e-16 Body mass index; TGCT cis rs7804356 0.651 rs55649724 chr7:26804005 G/A cg03456212 chr7:26904342 SKAP2 -0.54 -4.6 -0.38 1.04e-5 Type 1 diabetes; TGCT cis rs7267979 1.000 rs6083825 chr20:25366424 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9790314 0.846 rs4470535 chr3:160974468 G/A cg03342759 chr3:160939853 NMD3 -0.48 -5.23 -0.43 6.93e-7 Morning vs. evening chronotype; TGCT cis rs1497406 0.744 rs1007887 chr1:16509029 C/T cg20430773 chr1:16534157 ARHGEF19 0.56 6.28 0.49 5.24e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10782582 0.593 rs79552201 chr1:76215497 A/T cg03433033 chr1:76189801 ACADM -0.6 -6.63 -0.51 9.16e-10 Daytime sleep phenotypes; TGCT cis rs910316 1.000 rs10140851 chr14:75512612 G/A cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.97e-11 Height; TGCT cis rs3862435 0.572 rs2601183 chr15:90925721 T/G cg14166756 chr15:90894880 ZNF774 -0.32 -5.12 -0.42 1.14e-6 Response to exercise (triglyceride level interaction); TGCT cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg08280861 chr8:58055591 NA -0.37 -4.56 -0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg09737314 chr17:6899359 ALOX12 0.51 5.31 0.43 4.82e-7 Tonsillectomy; TGCT cis rs9393777 0.513 rs3999471 chr6:26650306 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs11779988 0.545 rs411531 chr8:17795934 A/G cg01800426 chr8:17659068 MTUS1 -0.68 -5.41 -0.44 3.14e-7 Breast cancer; TGCT cis rs6125597 0.805 rs6063382 chr20:47889958 C/T cg11220565 chr20:47934802 NA -0.3 -4.61 -0.38 9.8e-6 Intelligence (multi-trait analysis); TGCT cis rs240764 0.658 rs12664626 chr6:101195720 A/G cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs6087990 0.842 rs4911253 chr20:31352585 A/G cg13636640 chr20:31349939 DNMT3B 0.99 12.99 0.76 6.87e-25 Ulcerative colitis; TGCT cis rs6484504 0.553 rs7113880 chr11:31279557 A/G cg26647111 chr11:31128758 NA -0.35 -4.85 -0.4 3.58e-6 Red blood cell count; TGCT trans rs7615952 0.932 rs7630077 chr3:125649676 T/C cg07211511 chr3:129823064 LOC729375 -0.47 -7.68 -0.57 4.13e-12 Blood pressure (smoking interaction); TGCT cis rs4319547 0.656 rs10846664 chr12:122823777 C/T cg05707623 chr12:122985044 ZCCHC8 0.61 4.7 0.39 6.77e-6 Body mass index; TGCT cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs4072705 0.904 rs721863 chr9:127536267 A/T cg13476313 chr9:127244764 NR5A1 0.29 4.47 0.37 1.72e-5 Menarche (age at onset); TGCT cis rs3771570 1.000 rs59536819 chr2:242272388 A/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs9650657 0.707 rs7814757 chr8:10675188 T/C cg27411982 chr8:10470053 RP1L1 -0.22 -4.69 -0.39 7.17e-6 Neuroticism; TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg10108389 chr3:44770937 ZNF501 -0.49 -5.03 -0.41 1.7e-6 Depressive symptoms; TGCT cis rs10875595 0.836 rs4912747 chr5:140676027 T/A cg24830062 chr5:140700576 TAF7 -0.61 -5.14 -0.42 1.04e-6 Pulmonary function decline; TGCT cis rs7447593 0.666 rs10866705 chr5:176801131 G/T cg06060754 chr5:176797920 RGS14 -0.56 -8.3 -0.6 1.46e-13 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg25767906 chr1:53392781 SCP2 -0.59 -7.49 -0.56 1.12e-11 Monocyte count; TGCT cis rs13118159 0.836 rs12647145 chr4:1338618 C/A cg13395646 chr4:1353034 KIAA1530 -0.38 -4.64 -0.38 8.78e-6 Longevity; TGCT cis rs7524258 0.868 rs4908610 chr1:7311260 C/A cg04342483 chr1:7259290 CAMTA1 -0.31 -4.59 -0.38 1.06e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT trans rs561341 0.556 rs2470269 chr17:30406949 T/C cg20587970 chr11:113659929 NA -0.99 -8.11 -0.59 4.23e-13 Hip circumference adjusted for BMI; TGCT trans rs1496653 0.602 rs75709953 chr3:23442537 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs5750830 0.645 rs4821890 chr22:39777523 G/A cg11247378 chr22:39784982 NA -0.68 -9.79 -0.66 4.06e-17 Intelligence (multi-trait analysis); TGCT cis rs796364 0.950 rs56155997 chr2:200768491 C/T cg17644776 chr2:200775616 C2orf69 -0.31 -4.83 -0.4 3.99e-6 Schizophrenia; TGCT cis rs7267979 0.789 rs6083820 chr20:25354178 G/A cg21995068 chr20:25989032 LOC100134868 0.43 5.19 0.42 8.41e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6032067 0.636 rs6032093 chr20:43912167 A/G cg16667508 chr20:43936853 MATN4;RBPJL -0.48 -7.2 -0.54 5.02e-11 Blood protein levels; TGCT cis rs7267979 0.745 rs6132845 chr20:25547767 A/G cg14121845 chr20:25566513 NINL 0.47 5.0 0.41 1.91e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4409675 0.576 rs10794507 chr1:28216072 T/C cg23691781 chr1:28212827 C1orf38 0.25 5.26 0.43 6.19e-7 Corneal astigmatism; TGCT cis rs28595532 0.841 rs17258907 chr4:119769905 A/G cg21605333 chr4:119757512 SEC24D 1.55 8.04 0.59 6.15e-13 Cannabis dependence symptom count; TGCT cis rs478304 0.627 rs1073602 chr11:65455386 G/C cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.79e-13 Acne (severe); TGCT cis rs12478296 0.792 rs57482298 chr2:243011148 C/A cg06360820 chr2:242988706 NA -0.83 -5.68 -0.45 9.26e-8 Obesity-related traits; TGCT cis rs9913156 0.793 rs55682338 chr17:4582183 G/A cg00122941 chr17:4613640 ARRB2 0.87 7.49 0.56 1.14e-11 Lymphocyte counts; TGCT trans rs2727020 0.612 rs603672 chr11:49234566 T/A cg03929089 chr4:120376271 NA 0.71 7.84 0.58 1.79e-12 Coronary artery disease; TGCT cis rs7843479 0.562 rs6988010 chr8:21859084 G/A cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.11e-12 Mean corpuscular volume; TGCT cis rs1218582 0.772 rs4240874 chr1:154885779 C/T cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs8051431 0.840 rs8048292 chr16:72010484 T/C cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs1609391 0.567 rs835633 chr3:136676496 T/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs6733011 0.578 rs1878585 chr2:99501698 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.76 -0.39 5.3e-6 Bipolar disorder; TGCT cis rs9443189 0.570 rs659807 chr6:76293435 C/A cg01950844 chr6:76311363 SENP6 0.97 6.1 0.48 1.27e-8 Prostate cancer; TGCT cis rs6489882 0.548 rs1732773 chr12:113465611 T/G cg04001726 chr12:112547043 NAA25 -0.45 -4.49 -0.37 1.58e-5 Chronic lymphocytic leukemia; TGCT trans rs7342694 0.965 rs7189106 chr16:81907731 T/C cg04928372 chr6:27720905 NA 0.69 6.72 0.52 5.86e-10 Coronary artery disease; TGCT cis rs597539 0.616 rs473997 chr11:68639481 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.83 7.86 0.58 1.55e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2832191 0.720 rs2832194 chr21:30494250 T/C cg08807101 chr21:30365312 RNF160 -0.62 -5.74 -0.46 6.74e-8 Dental caries; TGCT cis rs2688608 0.933 rs2633307 chr10:75653881 G/A cg02947784 chr10:75434997 AGAP5 0.17 4.61 0.38 9.79e-6 Inflammatory bowel disease; TGCT cis rs4629710 0.645 rs35561719 chr6:131551244 G/A cg12606694 chr6:131520996 AKAP7 0.39 4.63 0.38 9.14e-6 Multiple myeloma (IgH translocation); TGCT cis rs4665809 0.887 rs2384324 chr2:26354239 A/G cg04944784 chr2:26401820 FAM59B -0.69 -6.37 -0.5 3.31e-9 Gut microbiome composition (summer); TGCT cis rs7666738 0.800 rs10028921 chr4:98962630 G/T cg17366294 chr4:99064904 C4orf37 0.73 7.35 0.55 2.31e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7586879 0.639 rs7580081 chr2:25097072 G/C cg01884057 chr2:25150051 NA 0.32 6.08 0.48 1.34e-8 Body mass index; TGCT trans rs4650994 0.967 rs4650992 chr1:178515135 A/T cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.52e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7412746 0.621 rs72704656 chr1:150828307 A/G cg09365446 chr1:150670422 GOLPH3L 0.35 4.98 0.41 2.11e-6 Melanoma; TGCT cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9388451 0.839 rs4897155 chr6:126095144 C/A cg05901451 chr6:126070800 HEY2 -1.02 -15.06 -0.8 8.78e-30 Brugada syndrome; TGCT cis rs2832191 1.000 rs2832185 chr21:30483761 C/G cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs75686122 0.892 rs75775215 chr8:104538884 C/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs1348850 0.757 rs2166554 chr2:178455824 A/G cg22681709 chr2:178499509 PDE11A -0.39 -4.88 -0.4 3.22e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9393777 0.720 rs57713596 chr6:27004098 C/T cg16898833 chr6:26189333 HIST1H4D 0.97 5.95 0.47 2.6e-8 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.802 rs73176694 chr22:41786788 C/T cg13695892 chr22:41940480 POLR3H -0.77 -7.47 -0.56 1.24e-11 Vitiligo; TGCT cis rs4925386 0.840 rs6143035 chr20:60920700 C/T cg06026331 chr20:60912101 LAMA5 -0.37 -6.23 -0.49 6.59e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs4689388 0.889 rs13101355 chr4:6293446 T/C cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9399135 0.933 rs7755680 chr6:135294259 A/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs7542091 0.506 rs992976 chr1:210066658 A/T cg23283495 chr1:209979779 IRF6 -0.47 -4.58 -0.38 1.14e-5 Monobrow; TGCT cis rs727505 1.000 rs10281582 chr7:124423688 A/G cg23710748 chr7:124431027 NA -0.26 -4.59 -0.38 1.07e-5 Lewy body disease; TGCT cis rs698833 0.509 rs10198291 chr2:44539009 C/T cg23552047 chr2:44669647 C2orf34 0.29 4.68 0.39 7.32e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs6089829 0.962 rs2314131 chr20:61665225 A/G cg18188782 chr20:61659543 NA 0.41 4.45 0.37 1.85e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs13217239 0.585 rs114919438 chr6:26963792 T/C cg26531700 chr6:26746687 NA -0.68 -6.65 -0.51 8.39e-10 Schizophrenia; TGCT cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs1150668 0.796 rs2247002 chr6:28397951 G/C cg19488431 chr6:28601329 NA 0.2 4.43 0.37 2.02e-5 Pubertal anthropometrics; TGCT cis rs425277 0.583 rs10910046 chr1:2041155 C/T cg24578937 chr1:2090814 PRKCZ -0.22 -5.27 -0.43 5.94e-7 Height; TGCT cis rs11098499 0.731 rs9995026 chr4:120490499 T/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs78487399 0.808 rs6544666 chr2:43732234 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.49 0.37 1.59e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4975709 0.569 rs4975743 chr5:1859941 G/T cg12288994 chr5:1860383 NA 0.24 4.52 0.38 1.42e-5 Cardiovascular disease risk factors; TGCT cis rs4319547 0.620 rs12372756 chr12:122815130 A/G cg05707623 chr12:122985044 ZCCHC8 -0.59 -4.53 -0.38 1.35e-5 Body mass index; TGCT cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg18305652 chr10:134549665 INPP5A 0.33 5.67 0.45 9.71e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2898290 0.592 rs2736342 chr8:11347289 A/C cg21775007 chr8:11205619 TDH -0.48 -4.57 -0.38 1.18e-5 Systolic blood pressure; TGCT cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs6733011 0.600 rs1356424 chr2:99425838 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.52 -5.19 -0.42 8.42e-7 Bipolar disorder; TGCT cis rs1153858 0.887 rs7171163 chr15:45636395 A/C cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs2243480 1.000 rs2533288 chr7:66056711 C/G cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs981844 0.754 rs897608 chr4:154754960 C/T cg14289246 chr4:154710475 SFRP2 0.98 8.88 0.62 6.38e-15 Response to statins (LDL cholesterol change); TGCT cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg23758822 chr17:41437982 NA 0.72 6.89 0.53 2.46e-10 Menopause (age at onset); TGCT cis rs6952808 0.792 rs35582663 chr7:1948756 G/A cg04267008 chr7:1944627 MAD1L1 -0.4 -5.44 -0.44 2.71e-7 Bipolar disorder and schizophrenia; TGCT cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs1982963 0.951 rs2516592 chr14:52503545 A/G cg10843707 chr14:52510701 NID2 -0.4 -6.41 -0.5 2.76e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2249625 0.523 rs2463702 chr6:72853778 A/G cg24401219 chr6:72892597 RIMS1 0.55 4.84 0.4 3.74e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs763014 0.931 rs2071982 chr16:630405 T/G cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs514406 0.505 rs269290 chr1:53167027 A/T cg08859206 chr1:53392774 SCP2 -0.34 -4.74 -0.39 5.65e-6 Monocyte count; TGCT cis rs7666738 0.649 rs28865589 chr4:98954279 C/A cg05340658 chr4:99064831 C4orf37 0.51 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs617219 0.710 rs10474578 chr5:78542290 T/C cg23514016 chr5:78407564 BHMT 0.32 4.87 0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6460942 1.000 rs6460942 chr7:12420989 T/C cg06484146 chr7:12443880 VWDE -0.58 -5.57 -0.45 1.5e-7 Coronary artery disease; TGCT cis rs9902453 0.709 rs6505162 chr17:28444183 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 7.53 0.56 9.27e-12 Coffee consumption (cups per day); TGCT cis rs7264396 0.790 rs8125090 chr20:34360015 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.31 -5.49 -0.44 2.17e-7 Total cholesterol levels; TGCT cis rs1008375 0.932 rs10029173 chr4:17659598 C/T cg10189774 chr4:17578691 LAP3 -0.58 -4.99 -0.41 1.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs73001065 0.591 rs57009615 chr19:19613622 A/G cg03709012 chr19:19516395 GATAD2A 0.9 5.58 0.45 1.46e-7 LDL cholesterol; TGCT cis rs6912958 0.559 rs107689 chr6:88069333 G/T cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.68 0.45 8.95e-8 Monocyte percentage of white cells; TGCT cis rs2180341 0.961 rs3798857 chr6:127659473 A/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs2456568 0.802 rs7101791 chr11:93638998 A/G cg16099599 chr11:93583650 C11orf90 -0.4 -5.12 -0.42 1.13e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1577917 0.916 rs12198730 chr6:86555138 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.42 -0.44 2.99e-7 Response to antipsychotic treatment; TGCT cis rs765787 0.530 rs12909987 chr15:45512207 C/T cg24006582 chr15:45444508 DUOX1 -0.24 -5.01 -0.41 1.84e-6 Uric acid levels; TGCT trans rs1005277 0.579 rs1740732 chr10:38491385 C/T cg17830980 chr10:43048298 ZNF37B -0.82 -10.24 -0.68 3.27e-18 Extrinsic epigenetic age acceleration; TGCT cis rs6125597 0.967 rs1079661 chr20:47850614 A/T cg11220565 chr20:47934802 NA -0.3 -4.6 -0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.933 rs1532042 chr17:28504389 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs877282 1.000 rs11253366 chr10:773386 C/T cg17470449 chr10:769945 NA 0.31 4.88 0.4 3.2e-6 Uric acid levels; TGCT trans rs7618501 1.000 rs11716575 chr3:49744890 A/G cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs16837677 0.649 rs16837622 chr1:156695504 C/T cg17331738 chr1:156647236 NES -0.68 -4.78 -0.39 4.83e-6 Sjögren's syndrome; TGCT cis rs4455778 0.894 rs4292636 chr7:49078125 C/A cg26309511 chr7:48887640 NA 0.45 5.23 0.43 6.97e-7 Lung cancer in never smokers; TGCT cis rs950169 0.922 rs62029585 chr15:84951874 C/G cg11189052 chr15:85197271 WDR73 0.82 6.2 0.49 7.83e-9 Schizophrenia; TGCT cis rs9921338 0.961 rs7199821 chr16:11425011 T/G cg00044050 chr16:11439710 C16orf75 -0.89 -6.53 -0.51 1.56e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9926296 0.715 rs2115401 chr16:89740609 A/G cg26513180 chr16:89883248 FANCA 0.63 6.12 0.48 1.13e-8 Vitiligo; TGCT cis rs826838 0.904 rs10876086 chr12:39188208 C/A cg26384229 chr12:38710491 ALG10B 0.98 8.78 0.62 1.07e-14 Heart rate; TGCT cis rs6860806 0.661 rs1588263 chr5:131577158 T/C cg24060327 chr5:131705240 SLC22A5 -0.58 -5.92 -0.47 2.93e-8 Breast cancer; TGCT cis rs317689 0.690 rs607797 chr12:69646010 T/C cg14784868 chr12:69753453 YEATS4 0.54 4.51 0.38 1.48e-5 Response to diuretic therapy; TGCT cis rs12142240 0.692 rs7532149 chr1:46824932 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs4819052 0.851 rs2236446 chr21:46678985 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.06 0.54 1.07e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12497850 0.897 rs6446252 chr3:48911125 C/T cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg22663859 chr13:21900854 NA 0.36 4.99 0.41 1.97e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs853679 0.506 rs1150711 chr6:28208535 T/C cg18815343 chr6:28367644 ZSCAN12 -0.47 -4.84 -0.4 3.71e-6 Depression; TGCT cis rs3806843 0.548 rs246058 chr5:140325134 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.82e-6 Obesity-related traits; TGCT cis rs11931598 0.783 rs28661210 chr4:7050956 C/A cg26116260 chr4:7069785 GRPEL1 0.54 4.8 0.4 4.54e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs12497850 0.931 rs11920534 chr3:48937761 G/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg13770153 chr20:60521292 NA -0.63 -7.95 -0.58 9.71e-13 Body mass index; TGCT cis rs12142240 0.698 rs17361791 chr1:46812519 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.84 0.46 4.33e-8 Menopause (age at onset); TGCT cis rs6964587 1.000 rs7785971 chr7:91736794 T/A cg17063962 chr7:91808500 NA 0.88 9.58 0.65 1.33e-16 Breast cancer; TGCT cis rs4478858 0.684 rs3766289 chr1:31760128 G/A cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs7659604 0.539 rs3217771 chr4:122739483 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.26 -0.43 6.07e-7 Type 2 diabetes; TGCT cis rs17473412 1.000 rs17408604 chr5:122726783 T/C cg15125798 chr5:122621645 NA -0.57 -5.13 -0.42 1.08e-6 Total body bone mineral density; TGCT cis rs651907 0.588 rs2860329 chr3:101632426 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.5 4.72 0.39 6.19e-6 Colorectal cancer; TGCT cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs1395 0.925 rs1659676 chr2:27399294 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.5 -6.74 -0.52 5.36e-10 Blood metabolite levels; TGCT cis rs826838 0.904 rs1554550 chr12:39208889 G/A cg13010199 chr12:38710504 ALG10B 0.77 6.09 0.48 1.31e-8 Heart rate; TGCT cis rs13242816 1.000 rs2402079 chr7:116128670 T/A cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs28595532 0.841 rs114175487 chr4:119733580 C/G cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs7726839 0.540 rs72703079 chr5:595173 T/C cg20362242 chr5:692897 TPPP 0.53 4.62 0.38 9.42e-6 Obesity-related traits; TGCT cis rs4851266 0.833 rs11685491 chr2:100858122 A/G cg22139774 chr2:100720529 AFF3 -0.32 -4.66 -0.39 7.89e-6 Educational attainment; TGCT cis rs11031096 0.727 rs2268168 chr11:4142069 C/T cg18678763 chr11:4115507 RRM1 -0.51 -6.59 -0.51 1.14e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2839186 0.934 rs2839194 chr21:47699437 T/G cg13732083 chr21:47605072 C21orf56 0.34 4.52 0.38 1.44e-5 Testicular germ cell tumor; TGCT cis rs3733585 0.699 rs6449174 chr4:9966422 C/T cg00071950 chr4:10020882 SLC2A9 -0.57 -6.66 -0.51 7.91e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs35306767 0.953 rs12762973 chr10:960761 C/G cg20503657 chr10:835505 NA 0.69 9.84 0.66 3.16e-17 Eosinophil percentage of granulocytes; TGCT cis rs6500602 0.647 rs4786514 chr16:4576798 A/C cg08645402 chr16:4508243 NA 0.22 5.58 0.45 1.43e-7 Schizophrenia; TGCT cis rs9527 0.518 rs4633383 chr10:104795723 T/G cg15744005 chr10:104629667 AS3MT -0.56 -4.52 -0.38 1.41e-5 Arsenic metabolism; TGCT cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs801193 1.000 rs7783924 chr7:66209057 A/C cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.97e-7 Aortic root size; TGCT cis rs2439831 0.681 rs825739 chr15:43592428 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.99 7.99 0.58 7.86e-13 Lung cancer in ever smokers; TGCT trans rs1814175 0.817 rs7481230 chr11:49772235 G/A cg11707556 chr5:10655725 ANKRD33B -0.38 -7.76 -0.57 2.75e-12 Height; TGCT cis rs7635838 0.827 rs9848170 chr3:11495983 G/C cg00170343 chr3:11313890 ATG7 0.62 5.54 0.45 1.72e-7 HDL cholesterol; TGCT cis rs853679 0.517 rs4713152 chr6:28137454 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs13242816 1.000 rs34295495 chr7:116068266 C/A cg02799643 chr7:116139180 CAV2 -0.44 -5.08 -0.42 1.33e-6 P wave duration; TGCT cis rs7611238 0.560 rs9809730 chr3:195075275 T/C cg27323046 chr3:195102265 ACAP2 0.36 4.85 0.4 3.65e-6 Body mass index; TGCT cis rs832540 0.931 rs702679 chr5:56221328 A/G cg12311346 chr5:56204834 C5orf35 -0.48 -5.02 -0.41 1.76e-6 Coronary artery disease; TGCT cis rs78456975 0.527 rs7590743 chr2:1575048 A/G cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2806561 0.704 rs636940 chr1:23522967 A/T cg12483005 chr1:23474871 LUZP1 0.42 5.41 0.44 3.15e-7 Height; TGCT cis rs1982963 0.901 rs1566131 chr14:52514684 G/A cg10843707 chr14:52510701 NID2 -0.43 -6.63 -0.51 9.33e-10 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs6089829 0.962 rs4809456 chr20:61660849 C/A cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs13064411 0.627 rs28710051 chr3:113143531 G/A cg18753928 chr3:113234510 CCDC52 -0.69 -5.23 -0.43 6.83e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs11715604 1 rs11715604 chr3:136589549 A/T cg15507776 chr3:136538369 TMEM22 -0.62 -4.58 -0.38 1.13e-5 B-cell malignancies (chronic lymphocytic leukemia, Hodgkin lymphoma or multiple myeloma) (pleiotropy); TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg19723775 chr5:179050963 HNRNPH1 0.51 5.18 0.42 8.81e-7 Lung cancer; TGCT cis rs9682041 0.877 rs10755126 chr3:170071694 C/G cg11886554 chr3:170076028 SKIL -0.56 -4.56 -0.38 1.19e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs11167764 0.945 rs6878397 chr5:141474012 A/G cg08523384 chr5:141488047 NDFIP1 -0.24 -4.91 -0.4 2.85e-6 Crohn's disease; TGCT cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7914558 1.000 rs7067970 chr10:104913870 C/T cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.66e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9300255 0.602 rs1727316 chr12:123618603 C/T cg00376283 chr12:123451042 ABCB9 0.67 5.27 0.43 5.78e-7 Neutrophil percentage of white cells; TGCT cis rs611744 0.967 rs595266 chr8:109193784 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs3617 0.591 rs11918800 chr3:52868145 G/A cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs4502686 chr4:98765117 T/C cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.512 rs5751153 chr22:42156561 T/C cg17554472 chr22:41940697 POLR3H 0.46 4.69 0.39 7.09e-6 Vitiligo; TGCT cis rs13064447 0.845 rs67698281 chr3:12774921 G/T cg20675869 chr3:12750130 NA -0.2 -5.14 -0.42 1.06e-6 Major depression and alcohol dependence; TGCT cis rs17122693 1.000 rs72679560 chr14:51067379 C/T cg04730355 chr14:51134070 SAV1 1.21 8.51 0.61 4.69e-14 Cognitive performance; TGCT cis rs8014204 0.870 rs3742790 chr14:75308758 C/T cg06637938 chr14:75390232 RPS6KL1 -0.7 -6.81 -0.52 3.69e-10 Caffeine consumption; TGCT cis rs1215050 0.716 rs11940331 chr4:99054041 G/C cg17366294 chr4:99064904 C4orf37 0.58 6.17 0.48 8.78e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7119038 0.774 rs11217001 chr11:118607046 G/A cg19308663 chr11:118741387 NA 0.26 4.86 0.4 3.52e-6 Sjögren's syndrome; TGCT cis rs34014631 1.000 rs80133219 chr10:103584701 T/C cg22630918 chr10:102748988 C10orf2 0.43 4.83 0.4 3.98e-6 Coronary artery calcification; TGCT cis rs763014 0.966 rs4247097 chr16:654224 G/A cg07343612 chr16:622815 PIGQ -0.42 -8.39 -0.6 9.08e-14 Height; TGCT cis rs78456975 0.527 rs72778003 chr2:1571487 G/A cg01028140 chr2:1542097 TPO -0.35 -5.17 -0.42 9.29e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT trans rs7618501 0.633 rs6446193 chr3:50059758 T/C cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs7568458 0.870 rs6733913 chr2:85757379 T/C cg02493740 chr2:85810744 VAMP5 -0.27 -4.81 -0.4 4.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs7666738 0.830 rs13136930 chr4:98937933 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.92 0.47 2.93e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2486288 0.656 rs12440356 chr15:45567529 T/C cg14582100 chr15:45693742 SPATA5L1 0.43 4.71 0.39 6.43e-6 Glomerular filtration rate; TGCT cis rs9302001 0.920 rs7997616 chr13:95454986 G/A cg07483244 chr13:95358924 NA 0.37 4.87 0.4 3.39e-6 Panic disorder; TGCT cis rs1992660 0.523 rs7707395 chr5:40343533 G/C cg01087697 chr5:40835557 RPL37 0.54 4.87 0.4 3.28e-6 Crohn's disease; TGCT cis rs7017914 0.967 rs6987007 chr8:71600942 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs7772486 0.790 rs11760 chr6:146205973 G/T cg23711669 chr6:146136114 FBXO30 0.89 10.18 0.67 4.61e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg08219700 chr8:58056026 NA 0.3 4.57 0.38 1.14e-5 Developmental language disorder (linguistic errors); TGCT cis rs7010267 0.542 rs4618726 chr8:120009385 C/A cg17171407 chr8:119960777 TNFRSF11B 0.27 5.01 0.41 1.82e-6 Total body bone mineral density (age 45-60); TGCT trans rs10953454 1.000 rs10243529 chr7:104494517 G/C cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs7010267 0.773 rs13277230 chr8:119922993 C/T cg17171407 chr8:119960777 TNFRSF11B -0.28 -4.94 -0.41 2.46e-6 Total body bone mineral density (age 45-60); TGCT cis rs36051895 0.589 rs6476946 chr9:5195275 C/G cg02405213 chr9:5042618 JAK2 0.75 9.34 0.64 4.9e-16 Pediatric autoimmune diseases; TGCT cis rs6570726 0.791 rs6914203 chr6:145899975 C/A cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10789491 1.000 rs4553120 chr1:47165729 C/T cg15501359 chr1:47185051 KIAA0494 0.82 8.26 0.6 1.82e-13 Response to hepatitis C treatment; TGCT cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg24531977 chr5:56204891 C5orf35 -0.77 -7.7 -0.57 3.71e-12 Initial pursuit acceleration; TGCT cis rs854765 0.603 rs854789 chr17:18026566 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.57 0.56 7.33e-12 Total body bone mineral density; TGCT cis rs854765 0.547 rs2955378 chr17:17930253 G/A cg04398451 chr17:18023971 MYO15A -0.32 -5.15 -0.42 1.01e-6 Total body bone mineral density; TGCT cis rs7103648 0.553 rs12803857 chr11:47890172 G/A cg20307385 chr11:47447363 PSMC3 0.78 7.19 0.54 5.29e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs6912958 0.874 rs2103764 chr6:88157392 T/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.74 -0.39 5.79e-6 Monocyte percentage of white cells; TGCT cis rs6570726 0.791 rs12208019 chr6:145935572 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.96 0.41 2.29e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.659 rs7225896 chr17:56637337 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs5750830 0.649 rs5750822 chr22:39826788 C/T cg02038168 chr22:39784481 NA -0.76 -6.66 -0.51 7.82e-10 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.790 rs2250387 chr6:146205233 C/T cg23711669 chr6:146136114 FBXO30 0.89 10.18 0.67 4.61e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs1050631 1.000 rs11873168 chr18:33707581 T/C cg25426722 chr18:33708991 SLC39A6;ELP2 0.49 4.73 0.39 5.92e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs7267979 0.932 rs367666 chr20:25449818 T/C cg03522245 chr20:25566470 NINL 0.61 6.54 0.51 1.46e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9393692 0.875 rs12526215 chr6:26262916 T/C cg13736514 chr6:26305472 NA -0.41 -5.76 -0.46 6.14e-8 Educational attainment; TGCT cis rs2228479 0.850 rs17227263 chr16:89810598 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs4713118 0.628 rs12179134 chr6:27675469 A/G cg20933634 chr6:27740509 NA 0.36 4.67 0.39 7.6e-6 Parkinson's disease; TGCT cis rs9914544 0.966 rs9915346 chr17:18787931 G/A cg26378065 chr17:18585709 ZNF286B 0.52 4.73 0.39 5.94e-6 Educational attainment (years of education); TGCT cis rs7647973 0.593 rs4855885 chr3:49690199 G/A cg03060546 chr3:49711283 APEH 0.63 5.33 0.43 4.49e-7 Menarche (age at onset); TGCT cis rs9527 0.545 rs35756290 chr10:104585572 G/A cg04362960 chr10:104952993 NT5C2 0.63 5.31 0.43 4.84e-7 Arsenic metabolism; TGCT cis rs1801251 1.000 rs6738386 chr2:233602028 T/C cg25237894 chr2:233734115 C2orf82 0.31 5.62 0.45 1.21e-7 Coronary artery disease; TGCT cis rs2288073 0.965 rs6545335 chr2:24422011 G/A cg05570707 chr2:24270316 C2orf44 -0.5 -4.47 -0.37 1.72e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs7336332 0.547 rs9581859 chr13:28035147 A/T cg22138327 chr13:27999177 GTF3A 0.73 5.1 0.42 1.22e-6 Weight; TGCT cis rs2404602 0.692 rs67570291 chr15:77020502 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs10504229 0.728 rs17804365 chr8:58151537 C/A cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg11845111 chr2:191398756 TMEM194B -0.36 -5.44 -0.44 2.73e-7 Pulse pressure; TGCT cis rs7772486 0.875 rs865913 chr6:146308874 C/T cg05347473 chr6:146136440 FBXO30 0.54 5.0 0.41 1.91e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs76473307 1.000 rs6026543 chr20:57394025 G/A cg06163629 chr20:57414884 GNASAS;GNAS -0.67 -4.53 -0.38 1.34e-5 Chronic lymphocytic leukemia; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg23131131 chr22:24373011 LOC391322 -0.68 -7.1 -0.54 8.42e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg23609682 chr1:3070786 PRDM16 0.53 7.65 0.57 4.85e-12 Breast cancer; TGCT cis rs72945132 1.000 rs72945132 chr11:70113901 G/C cg00319359 chr11:70116639 PPFIA1 0.96 6.83 0.52 3.35e-10 Coronary artery disease; TGCT cis rs3733585 0.648 rs13103497 chr4:9979262 A/G cg00071950 chr4:10020882 SLC2A9 0.57 6.68 0.51 7.18e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6901250 0.788 rs591794 chr6:117089018 G/A cg12892004 chr6:117198278 RFX6 0.51 6.28 0.49 5.29e-9 C-reactive protein levels; TGCT cis rs5769765 1.000 rs768618 chr22:50286827 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs12908161 0.959 rs11637728 chr15:85203392 A/T cg11189052 chr15:85197271 WDR73 0.75 6.23 0.49 6.54e-9 Schizophrenia; TGCT cis rs10411936 1.000 rs7256818 chr19:16558766 C/A cg14704714 chr19:15740395 CYP4F8 -0.26 -4.57 -0.38 1.17e-5 White blood cell count;Multiple sclerosis; TGCT cis rs76419734 0.510 rs17036102 chr4:106603098 C/T cg24545054 chr4:106630052 GSTCD;INTS12 -0.67 -4.76 -0.39 5.26e-6 Post bronchodilator FEV1; TGCT trans rs9329221 0.741 rs56243511 chr8:9805695 T/C cg15556689 chr8:8085844 FLJ10661 -0.82 -7.76 -0.57 2.71e-12 Neuroticism; TGCT cis rs42648 0.935 rs42629 chr7:89963324 G/T cg25739043 chr7:89950458 NA -0.75 -7.61 -0.56 5.9e-12 Homocysteine levels; TGCT cis rs669446 0.533 rs11210913 chr1:44222597 G/A cg12908607 chr1:44402522 ARTN -0.61 -7.12 -0.54 7.51e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs6988636 0.534 rs62520600 chr8:124095405 G/A cg27053337 chr8:124217698 FAM83A 0.53 4.45 0.37 1.92e-5 Urinary uromodulin levels; TGCT cis rs9677476 1.000 rs12470450 chr2:232113888 T/A cg07929768 chr2:232055508 NA 0.3 4.48 0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs514406 0.861 rs505444 chr1:53251860 C/T cg25767906 chr1:53392781 SCP2 -0.49 -5.7 -0.46 8.18e-8 Monocyte count; TGCT cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg04944784 chr2:26401820 FAM59B -0.75 -6.16 -0.48 9.33e-9 Gut microbiome composition (summer); TGCT cis rs10276381 0.579 rs11520706 chr7:28202748 C/T cg23620719 chr7:28220237 JAZF1 -0.96 -5.21 -0.42 7.59e-7 Crohn's disease; TGCT trans rs4824093 0.610 rs73441745 chr22:50237606 G/A cg09872104 chr7:134855509 C7orf49 -0.91 -7.32 -0.55 2.66e-11 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7611238 0.560 rs7639146 chr3:195094971 T/C cg27323046 chr3:195102265 ACAP2 0.37 4.93 0.4 2.56e-6 Body mass index; TGCT cis rs28595532 0.920 rs115690307 chr4:119768289 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs11190604 0.767 rs4919458 chr10:102177728 G/A cg23241863 chr10:102295624 HIF1AN -0.64 -4.89 -0.4 3.02e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6582630 0.502 rs1607867 chr12:38385463 C/T cg13010199 chr12:38710504 ALG10B 0.59 4.64 0.38 8.86e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs853679 0.517 rs9393901 chr6:28136797 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs4476553 0.935 rs12696704 chr4:4711210 C/T cg05554346 chr4:4145468 NA 0.4 4.69 0.39 7.13e-6 Response to amphetamines; TGCT cis rs4819052 0.620 rs421619 chr21:46546115 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.63 4.99 0.41 2.03e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9653442 0.527 rs13003982 chr2:100759078 T/C cg22139774 chr2:100720529 AFF3 -0.37 -5.7 -0.46 8.36e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1348850 0.567 rs3770011 chr2:178537890 C/T cg22681709 chr2:178499509 PDE11A -0.48 -6.08 -0.48 1.4e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs3087591 1.000 rs2952989 chr17:29516113 G/A cg24425628 chr17:29625626 OMG;NF1 0.45 7.11 0.54 8.22e-11 Hip circumference; TGCT cis rs7659604 0.676 rs4516739 chr4:122699741 G/T cg06713675 chr4:122721982 EXOSC9 -0.6 -8.25 -0.6 1.95e-13 Type 2 diabetes; TGCT cis rs9677476 0.516 rs1025107 chr2:232034342 C/T cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs9303401 0.527 rs7224468 chr17:56749943 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.61 5.41 0.44 3.12e-7 Cognitive test performance; TGCT cis rs854765 0.533 rs2955354 chr17:17948716 G/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6831352 0.879 rs2602888 chr4:100041706 C/T cg12011299 chr4:100065546 ADH4 0.4 4.77 0.39 5.18e-6 Alcohol dependence; TGCT cis rs10791097 0.720 rs6590517 chr11:130733505 C/T cg14779329 chr11:130786720 SNX19 0.3 5.11 0.42 1.2e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7095607 0.606 rs4746738 chr10:69959837 C/T cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs6570726 0.791 rs365747 chr6:145866784 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs3617 0.539 rs9880619 chr3:52953055 G/A cg05573699 chr3:52720067 GNL3;PBRM1 0.46 4.49 0.37 1.58e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs11190604 1.000 rs12219158 chr10:102302923 T/C cg16342193 chr10:102329863 NA -0.4 -4.89 -0.4 3.08e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11864453 0.560 rs6499561 chr16:72148404 A/G cg14768367 chr16:72042858 DHODH 0.51 4.89 0.4 3.11e-6 Fibrinogen levels; TGCT cis rs4820539 0.966 rs5759594 chr22:23470660 G/A cg21100191 chr22:23484243 RTDR1 0.89 10.61 0.69 4.23e-19 Bone mineral density; TGCT cis rs6121246 0.529 rs6088814 chr20:30218172 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs79349575 0.749 rs957557 chr17:47003221 G/T cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs1008375 0.646 rs13145480 chr4:17565143 T/C cg18681998 chr4:17616180 MED28 -0.74 -6.67 -0.51 7.39e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1799949 1.000 rs2271574 chr17:41327648 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg21724239 chr8:58056113 NA 0.49 5.23 0.43 6.92e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.505 rs427319 chr1:53178807 T/G cg22166914 chr1:53195759 ZYG11B 0.45 8.14 0.59 3.47e-13 Monocyte count; TGCT cis rs2066819 1.000 rs77768890 chr12:56725121 A/G cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs3782455 1.000 rs116855053 chr12:114403055 C/T cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2066819 1.000 rs871130 chr12:56648777 A/G cg26714650 chr12:56694279 CS 1.33 6.24 0.49 6.46e-9 Psoriasis vulgaris; TGCT cis rs815815 0.608 rs815808 chr2:47381097 C/T cg27223769 chr2:47403360 CALM2 0.58 5.31 0.43 4.8e-7 Dialysis-related mortality; TGCT cis rs9796 0.866 rs516156 chr15:41381257 A/G cg18705301 chr15:41695430 NDUFAF1 -0.47 -6.09 -0.48 1.34e-8 Menopause (age at onset); TGCT cis rs17376456 0.569 rs11135397 chr5:93214975 G/T cg21475434 chr5:93447410 FAM172A 0.68 5.24 0.43 6.61e-7 Diabetic retinopathy; TGCT cis rs13040088 1.000 rs2295000 chr20:61536938 A/G cg23096297 chr20:61557774 DIDO1 -1.2 -10.17 -0.67 4.96e-18 Menopause (age at onset); TGCT cis rs1061377 1.000 rs9997089 chr4:39120883 T/C cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs734999 0.967 rs10797433 chr1:2502010 T/C cg18854424 chr1:2615690 NA 0.47 5.86 0.47 3.94e-8 Ulcerative colitis; TGCT cis rs769267 0.930 rs4808964 chr19:19603692 A/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.65 -5.44 -0.44 2.74e-7 Tonsillectomy; TGCT cis rs7412746 0.611 rs12085336 chr1:150775780 A/T cg09365446 chr1:150670422 GOLPH3L 0.36 5.38 0.44 3.58e-7 Melanoma; TGCT cis rs826838 0.967 rs1684413 chr12:39128704 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs6558174 0.802 rs3758040 chr8:22487087 T/C cg03733263 chr8:22462867 KIAA1967 0.58 4.62 0.38 9.62e-6 Breast cancer; TGCT trans rs7726839 0.540 rs12517638 chr5:645484 C/T cg25482853 chr8:67687455 SGK3 1.19 10.3 0.68 2.4e-18 Obesity-related traits; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg02953382 chr22:24373134 LOC391322 -0.81 -9.29 -0.64 6.56e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs74181299 0.892 rs2540945 chr2:65289825 A/G cg05010058 chr2:65284262 CEP68 0.43 4.72 0.39 6.15e-6 Pulse pressure; TGCT cis rs9399135 0.933 rs41294852 chr6:135376379 T/G cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs4555082 0.834 rs2816607 chr14:105718385 A/T cg01266790 chr14:105781312 PACS2 0.55 4.53 0.38 1.35e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs62380364 0.566 rs1705565 chr5:88048457 C/T cg24804195 chr5:87968844 LOC645323 -0.58 -5.68 -0.45 9.18e-8 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.850 rs7181039 chr15:44179112 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.83 5.71 0.46 7.85e-8 Lung cancer in ever smokers; TGCT cis rs2224391 0.628 rs2753240 chr6:5254124 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.99 -6.43 -0.5 2.46e-9 Height; TGCT cis rs11105298 0.891 rs6538190 chr12:89885942 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs12477438 0.501 rs13008171 chr2:99743419 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg20007245 chr22:24372913 LOC391322 -0.78 -8.31 -0.6 1.43e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs72781680 1.000 rs72796358 chr2:24160132 T/A cg08917208 chr2:24149416 ATAD2B 0.73 4.5 0.37 1.58e-5 Lymphocyte counts; TGCT cis rs36051895 0.623 rs7870536 chr9:5245493 C/T cg02405213 chr9:5042618 JAK2 -0.7 -8.94 -0.63 4.42e-15 Pediatric autoimmune diseases; TGCT cis rs7681423 1.000 rs7654093 chr4:155545072 A/T cg20735720 chr4:155535218 FGG -0.49 -7.57 -0.56 7.2e-12 Fibrinogen; TGCT cis rs4654899 1.000 rs6426656 chr1:21343245 G/C cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2562456 0.917 rs2562471 chr19:21715819 C/T cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs1150668 0.796 rs2531825 chr6:28349264 C/T cg13525197 chr6:28411240 ZSCAN23 -0.52 -5.08 -0.41 1.37e-6 Pubertal anthropometrics; TGCT cis rs137603 0.562 rs470080 chr22:39712368 C/T cg17798944 chr22:39715225 SNORD43;RPL3 -0.62 -6.47 -0.5 2.04e-9 Primary biliary cholangitis; TGCT cis rs3820928 0.967 rs720501 chr2:227778445 C/T cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs12579753 1.000 rs7956826 chr12:82173365 A/G cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs3806843 0.705 rs2530230 chr5:140088131 G/A cg19875535 chr5:140030758 IK -0.38 -6.33 -0.49 4.09e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2204008 0.837 rs4312131 chr12:38181087 G/T cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg11502198 chr6:26597334 ABT1 0.54 4.87 0.4 3.4e-6 Intelligence (multi-trait analysis); TGCT cis rs4849845 0.598 rs11690576 chr2:121019800 A/G cg24070213 chr2:121070622 NA -0.34 -4.74 -0.39 5.83e-6 Mean platelet volume; TGCT cis rs5167 0.750 rs3786505 chr19:45490570 A/G cg13119609 chr19:45449297 APOC2 0.23 4.73 0.39 5.98e-6 Blood protein levels; TGCT cis rs7104764 1.000 rs10902110 chr11:237648 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs911555 0.504 rs8006526 chr14:104075015 T/C cg26031613 chr14:104095156 KLC1 0.61 5.6 0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs2115630 0.936 rs11073663 chr15:85260268 A/G cg17173187 chr15:85201210 NMB -0.4 -5.04 -0.41 1.58e-6 P wave terminal force; TGCT cis rs7666738 0.830 rs13149404 chr4:99070236 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs763014 1.000 rs2269558 chr16:682250 C/T cg09263875 chr16:632152 PIGQ 0.3 6.75 0.52 4.97e-10 Height; TGCT cis rs838147 0.508 rs507711 chr19:49208564 C/T cg13540341 chr19:49222985 MAMSTR -0.38 -4.93 -0.41 2.53e-6 Dietary macronutrient intake; TGCT cis rs2562456 0.833 rs2928211 chr19:21541297 A/G cg01304269 chr19:21688519 ZNF429 -0.54 -4.44 -0.37 1.97e-5 Pain; TGCT cis rs10875746 0.669 rs2279464 chr12:48690409 C/T cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.02 8.28 0.6 1.66e-13 Platelet count; TGCT cis rs12989701 0.778 rs7584040 chr2:127863224 C/T cg08168897 chr2:127865431 BIN1 0.36 4.49 0.37 1.58e-5 Alzheimer's disease (late onset); TGCT cis rs12579753 1.000 rs17748942 chr12:82170478 G/A cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs758129 0.578 rs1006660 chr15:89883520 T/C cg24365117 chr15:89879190 POLG 0.34 4.67 0.39 7.84e-6 Schizophrenia; TGCT cis rs12220898 0.679 rs10745257 chr10:50473892 T/C cg06072769 chr10:50146962 WDFY4 0.36 4.67 0.39 7.64e-6 Inflammatory biomarkers; TGCT cis rs7267979 0.966 rs2145126 chr20:25263648 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9325144 0.560 rs1843911 chr12:38676585 C/T cg13010199 chr12:38710504 ALG10B -0.53 -4.63 -0.38 9.02e-6 Morning vs. evening chronotype; TGCT cis rs10795061 0.576 rs10904074 chr10:3710962 G/A cg13668419 chr10:3197757 PITRM1 -0.18 -4.87 -0.4 3.31e-6 Subjective well-being; TGCT cis rs28493229 0.708 rs10425069 chr19:41152847 C/T cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.14 0.42 1.03e-6 Kawasaki disease; TGCT cis rs3820928 0.692 rs2396434 chr2:227775223 G/T cg11843606 chr2:227700838 RHBDD1 -0.57 -5.4 -0.44 3.3e-7 Pulmonary function; TGCT cis rs9549260 0.755 rs7335520 chr13:41196407 C/T cg21288729 chr13:41239152 FOXO1 1.01 10.05 0.67 9.71e-18 Red blood cell count; TGCT cis rs858239 0.537 rs6955115 chr7:23227144 A/G cg05602783 chr7:23145260 KLHL7 -0.71 -5.55 -0.45 1.68e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6964587 1.000 rs10228334 chr7:91713972 C/T cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs7666738 0.830 rs62321569 chr4:98984250 T/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7829975 0.714 rs11784052 chr8:8671962 C/T cg06636001 chr8:8085503 FLJ10661 0.6 5.43 0.44 2.86e-7 Mood instability; TGCT cis rs74233809 1.000 rs11191502 chr10:104765494 T/G cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs11190604 0.945 rs11190553 chr10:102207959 T/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11644362 0.932 rs34290494 chr16:12987705 A/C cg06890432 chr16:12997467 SHISA9 -0.6 -6.49 -0.5 1.88e-9 Positive affect;Subjective well-being; TGCT cis rs28595532 0.920 rs55901549 chr4:119770172 T/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs3771570 0.901 rs28433352 chr2:242339656 A/G cg21155796 chr2:242212141 HDLBP 0.84 6.3 0.49 4.66e-9 Prostate cancer; TGCT cis rs875971 0.660 rs7807930 chr7:66087165 C/T cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg11062466 chr8:58055876 NA 0.43 4.64 0.38 8.85e-6 Developmental language disorder (linguistic errors); TGCT cis rs751728 0.664 rs747694 chr6:33736490 A/G cg13859433 chr6:33739653 LEMD2 -0.32 -5.93 -0.47 2.78e-8 Crohn's disease; TGCT cis rs9899728 0.764 rs7219493 chr17:73044188 T/C cg27626185 chr17:73056755 KCTD2 -0.66 -6.31 -0.49 4.52e-9 Alzheimer's disease or small vessel stroke; TGCT cis rs17376456 0.757 rs6859757 chr5:93206042 C/T cg21475434 chr5:93447410 FAM172A 0.71 4.92 0.4 2.69e-6 Diabetic retinopathy; TGCT cis rs4851266 0.966 rs12987662 chr2:100821548 C/A cg22139774 chr2:100720529 AFF3 -0.36 -5.4 -0.44 3.26e-7 Educational attainment; TGCT cis rs2456568 0.709 rs12806128 chr11:93634972 C/T cg16099599 chr11:93583650 C11orf90 0.39 4.63 0.38 9.05e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2180341 0.961 rs7775493 chr6:127615000 C/A cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs11098499 0.754 rs12506487 chr4:120271361 T/G cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.05e-7 Corneal astigmatism; TGCT cis rs67311347 0.503 rs11719968 chr3:40241600 G/T cg13683864 chr3:40499215 RPL14 -0.76 -6.95 -0.53 1.85e-10 Renal cell carcinoma; TGCT cis rs3806843 0.576 rs405192 chr5:140324710 T/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.11e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9611565 0.512 rs5758464 chr22:42171300 A/G cg13695892 chr22:41940480 POLR3H 0.99 7.04 0.53 1.16e-10 Vitiligo; TGCT cis rs9906944 0.742 rs4073893 chr17:47118523 A/G cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs10746514 1.000 rs1576618 chr1:232244331 A/G cg09506761 chr1:232265262 NA -0.46 -4.77 -0.39 5.07e-6 Response to statin therapy; TGCT cis rs7666738 0.791 rs34790496 chr4:98930516 C/T cg18180107 chr4:99064573 C4orf37 0.55 4.98 0.41 2.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7959452 0.868 rs10784774 chr12:69737879 C/T cg14784868 chr12:69753453 YEATS4 -0.65 -6.87 -0.53 2.76e-10 Blood protein levels; TGCT cis rs7584330 0.955 rs6729659 chr2:238385126 T/C cg14458575 chr2:238380390 NA 0.5 7.75 0.57 2.9e-12 Prostate cancer; TGCT cis rs9308731 0.583 rs4848406 chr2:111933758 G/A cg04202892 chr2:111875749 ACOXL 0.44 4.88 0.4 3.2e-6 Chronic lymphocytic leukemia; TGCT cis rs4665809 1.000 rs6546736 chr2:26293878 C/T cg22920501 chr2:26401640 FAM59B 0.74 6.4 0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs9381040 0.701 rs6933231 chr6:41163700 T/C cg03526776 chr6:41159608 TREML2 0.28 6.06 0.48 1.48e-8 Alzheimer's disease (late onset); TGCT cis rs74233809 1.000 rs12413409 chr10:104719096 C/T cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg24531977 chr5:56204891 C5orf35 0.89 7.5 0.56 1.04e-11 Initial pursuit acceleration; TGCT cis rs12497850 0.897 rs6781790 chr3:49044767 C/T cg07636037 chr3:49044803 WDR6 0.96 10.9 0.7 8.39e-20 Parkinson's disease; TGCT trans rs1496653 0.602 rs35240920 chr3:23318144 T/C cg02770683 chr12:57597238 LRP1 0.36 6.66 0.51 8.06e-10 Type 2 diabetes; TGCT cis rs3796352 1.000 rs13058817 chr3:53024139 C/T cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1552244 0.882 rs13064570 chr3:9997545 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.73 -0.52 5.62e-10 Alzheimer's disease; TGCT cis rs17102423 0.594 rs942626 chr14:65550082 C/T cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.57e-9 Obesity-related traits; TGCT cis rs72945132 0.522 rs4367974 chr11:70248900 C/T cg00319359 chr11:70116639 PPFIA1 0.9 7.21 0.54 4.9e-11 Coronary artery disease; TGCT cis rs6570726 0.791 rs10872577 chr6:145900560 G/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.861 rs12150493 chr17:37586154 T/C cg15445000 chr17:37608096 MED1 0.32 4.68 0.39 7.47e-6 Glomerular filtration rate (creatinine); TGCT cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg15659132 chr6:26577336 NA 0.84 10.91 0.7 7.83e-20 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.816 rs56387520 chr3:10042782 C/T cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs4455778 0.580 rs12718320 chr7:49109447 A/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.83e-9 Lung cancer in never smokers; TGCT cis rs457287 0.772 rs412457 chr9:4825277 C/G cg21184111 chr9:4792285 RCL1 -0.48 -4.8 -0.4 4.55e-6 Platelet count; TGCT cis rs4253772 0.530 rs6008616 chr22:46707954 A/G cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs66887589 0.616 rs11098497 chr4:120187068 C/T cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.14e-5 Diastolic blood pressure; TGCT cis rs1023500 1.000 rs9620001 chr22:42330229 T/C cg04692870 chr22:42525206 CYP2D6 -0.35 -5.28 -0.43 5.57e-7 Schizophrenia; TGCT cis rs807669 0.544 rs2040771 chr22:19161935 C/T cg02655711 chr22:19163373 SLC25A1 0.26 5.07 0.41 1.39e-6 Metabolite levels; TGCT cis rs11785693 0.862 rs6990234 chr8:4996812 A/G cg26367366 chr8:4980734 NA 0.57 4.53 0.38 1.38e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs12484776 0.677 rs8136580 chr22:40530923 T/C cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10946940 0.965 rs4713112 chr6:27516833 G/T cg10876282 chr6:28092338 ZSCAN16 -0.47 -4.76 -0.39 5.34e-6 Systemic lupus erythematosus; TGCT cis rs7927592 0.513 rs3853616 chr11:68198252 A/G cg16797656 chr11:68205561 LRP5 0.27 4.93 0.4 2.62e-6 Total body bone mineral density; TGCT cis rs611744 0.967 rs673854 chr8:109191838 G/A cg21045802 chr8:109455806 TTC35 0.51 4.57 0.38 1.17e-5 Dupuytren's disease; TGCT cis rs2412208 0.509 rs7546792 chr1:7124346 C/T cg20434152 chr1:7120926 CAMTA1 -0.29 -4.64 -0.38 8.64e-6 Survival in sporadic amyotrophic lateral sclerosis; TGCT cis rs10504229 0.636 rs114725691 chr8:58054292 C/T cg08280861 chr8:58055591 NA 0.35 4.88 0.4 3.2e-6 Developmental language disorder (linguistic errors); TGCT cis rs2880765 0.835 rs11638498 chr15:86023018 T/C cg13263323 chr15:86062960 AKAP13 -0.23 -4.99 -0.41 2e-6 Coronary artery disease; TGCT cis rs1107366 0.505 rs12489314 chr3:125976864 A/G cg01346077 chr3:125931526 NA 0.28 4.93 0.4 2.58e-6 Metabolite levels; TGCT cis rs3087591 0.960 rs2952998 chr17:29418412 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 6.9 0.53 2.36e-10 Hip circumference; TGCT cis rs12360000 0.897 rs7921481 chr10:1898756 A/C cg26364871 chr10:1889757 NA -0.47 -5.26 -0.43 5.99e-7 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs3780378 1.000 rs10117591 chr9:5094539 G/A cg02405213 chr9:5042618 JAK2 -0.6 -7.82 -0.57 1.94e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs3858526 1.000 rs11039787 chr11:5965611 C/T cg05234568 chr11:5960015 NA -0.43 -4.47 -0.37 1.74e-5 DNA methylation (variation); TGCT cis rs2227564 0.620 rs3812637 chr10:75568846 C/T cg19442545 chr10:75533431 FUT11 -0.31 -4.55 -0.38 1.27e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9443645 0.810 rs9448610 chr6:79739622 G/A cg09184832 chr6:79620586 NA -0.45 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.582 rs10786689 chr10:104356359 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7508 0.612 rs10112857 chr8:17917888 A/G cg01800426 chr8:17659068 MTUS1 -0.52 -4.52 -0.38 1.44e-5 Atrial fibrillation; TGCT cis rs17376456 0.877 rs28539612 chr5:93499099 C/T cg21475434 chr5:93447410 FAM172A 0.63 4.63 0.38 8.98e-6 Diabetic retinopathy; TGCT cis rs9430161 0.579 rs77578010 chr1:11035758 G/A cg27631724 chr1:11040367 C1orf127 0.55 6.05 0.48 1.6e-8 Ewing sarcoma; TGCT trans rs1814175 0.935 rs7925863 chr11:49615802 C/A cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs7666738 0.830 rs17027102 chr4:98919221 A/G cg05340658 chr4:99064831 C4orf37 -0.53 -6.06 -0.48 1.49e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs7618501 0.602 rs2245365 chr3:50097319 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -4.94 -0.41 2.45e-6 Coronary artery disease; TGCT cis rs9611565 0.559 rs12483860 chr22:41961916 C/T cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs60154123 0.505 rs76101197 chr1:210044089 T/C cg12034118 chr1:209979487 IRF6 0.65 4.56 0.38 1.2e-5 Coronary artery disease; TGCT cis rs936229 0.705 rs936227 chr15:75131959 A/G cg10253484 chr15:75165896 SCAMP2 -0.51 -4.77 -0.39 5.14e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs1552244 0.608 rs6764807 chr3:9998803 T/C cg00149659 chr3:10157352 C3orf10 0.65 4.8 0.4 4.49e-6 Alzheimer's disease; TGCT cis rs28374715 0.681 rs77187862 chr15:41619276 A/T cg18705301 chr15:41695430 NDUFAF1 -0.87 -12.32 -0.74 2.82e-23 Ulcerative colitis; TGCT cis rs11690935 0.921 rs10200608 chr2:172597929 G/A cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.41 -0.74 1.75e-23 Schizophrenia; TGCT cis rs5769707 0.521 rs6009805 chr22:50058715 T/C cg05373962 chr22:49881684 NA -0.32 -5.46 -0.44 2.46e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6089584 0.927 rs3787427 chr20:60579789 T/C cg13770153 chr20:60521292 NA -0.53 -7.2 -0.54 5.01e-11 Body mass index; TGCT cis rs9467711 0.606 rs1977 chr6:26377546 A/G cg16898833 chr6:26189333 HIST1H4D 1.04 5.26 0.43 6.22e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.830 rs13130923 chr4:99046281 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9811920 0.690 rs7623587 chr3:99906751 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.44 -5.29 -0.43 5.41e-7 Axial length; TGCT cis rs611744 0.608 rs612744 chr8:109245991 G/A cg21045802 chr8:109455806 TTC35 0.74 7.37 0.55 2.07e-11 Dupuytren's disease; TGCT cis rs4919669 0.719 rs17114803 chr10:104386934 A/G cg05855489 chr10:104503620 C10orf26 0.71 4.69 0.39 7.18e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT trans rs10802346 0.545 rs6662672 chr1:246387611 A/C cg13514129 chr1:39547527 MACF1 0.96 8.52 0.61 4.45e-14 Fractional exhaled nitric oxide (childhood); TGCT cis rs13326165 0.760 rs13059674 chr3:52371789 T/G cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.5 5.41 0.44 3.18e-7 Lymphocyte counts; TGCT cis rs6909279 0.678 rs11155795 chr6:151851339 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.61 -5.67 -0.45 9.49e-8 Bone mineral density; TGCT trans rs10435719 0.773 rs7842810 chr8:11794163 A/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs11148252 0.538 rs9535885 chr13:52726524 A/G cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.85e-8 Lewy body disease; TGCT cis rs10193935 0.901 rs7594010 chr2:42534896 C/T cg27598129 chr2:42591480 NA -0.41 -5.65 -0.45 1.04e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9583531 0.628 rs9521914 chr13:111382231 C/A cg24331049 chr13:111365604 ING1 0.81 8.0 0.58 7.56e-13 Coronary artery disease; TGCT cis rs17253792 0.822 rs10147431 chr14:56091841 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs1150668 0.799 rs1150705 chr6:28193786 T/G cg11262757 chr6:27280423 POM121L2 0.45 4.44 0.37 1.94e-5 Pubertal anthropometrics; TGCT cis rs12497850 0.931 rs13315711 chr3:48986399 A/T cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.98e-6 Parkinson's disease; TGCT cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg15659132 chr6:26577336 NA 0.87 11.0 0.7 4.77e-20 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.755 rs2103633 chr6:145894021 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs875971 0.965 rs6971509 chr7:65714970 G/T cg11764359 chr7:65958608 NA -0.61 -5.52 -0.44 1.93e-7 Aortic root size; TGCT cis rs7674212 0.531 rs4699048 chr4:103926727 A/G cg16532752 chr4:104119610 CENPE -0.6 -5.29 -0.43 5.33e-7 Type 2 diabetes; TGCT cis rs9527 0.615 rs10883800 chr10:104671212 A/C cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs4819052 0.819 rs8134084 chr21:46693295 G/A cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.5 -4.45 -0.37 1.92e-5 Prudent dietary pattern; TGCT cis rs1865760 0.865 rs1436306 chr6:25948421 A/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg12310025 chr6:25882481 NA -0.65 -6.72 -0.52 6.03e-10 Blood metabolite levels; TGCT cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.67 -0.78 1.61e-26 Renal cell carcinoma; TGCT cis rs9394841 0.667 rs12661667 chr6:41792545 C/T cg08135965 chr6:41755394 TOMM6 0.54 5.06 0.41 1.45e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs6430585 0.591 rs75223002 chr2:136525309 G/T cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs6835098 0.961 rs17322893 chr4:174122556 A/G cg08422745 chr4:174089978 GALNT7 0.89 10.02 0.67 1.11e-17 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs12711979 0.509 rs13021385 chr2:3826387 T/C cg17052675 chr2:3827356 NA -0.55 -12.72 -0.75 3.04e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs11792861 0.816 rs2304779 chr9:111670513 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.51 -4.79 -0.4 4.61e-6 Menarche (age at onset); TGCT cis rs1568889 1.000 rs12287732 chr11:28120845 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs4665809 0.941 rs1470096 chr2:26311482 T/C cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs7666738 0.791 rs6828752 chr4:99063382 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2637266 0.739 rs2395404 chr10:78380513 G/T cg18941641 chr10:78392320 NA 0.4 4.69 0.39 7.01e-6 Pulmonary function; TGCT cis rs769267 0.965 rs12460764 chr19:19431963 G/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs35883536 0.647 rs1855630 chr1:101039979 C/G cg06223162 chr1:101003688 GPR88 -0.43 -8.27 -0.6 1.73e-13 Monocyte count; TGCT cis rs9682041 0.867 rs6444925 chr3:170123358 G/T cg11886554 chr3:170076028 SKIL 0.93 6.65 0.51 8.31e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs58688157 0.549 rs11246192 chr11:572473 T/C cg27205902 chr11:1006985 AP2A2 0.27 4.47 0.37 1.76e-5 Systemic lupus erythematosus; TGCT cis rs2404602 0.692 rs1116535 chr15:77009514 C/G cg22467129 chr15:76604101 ETFA 0.44 4.98 0.41 2.07e-6 Blood metabolite levels; TGCT cis rs7819412 0.522 rs4291231 chr8:10990164 G/A cg21775007 chr8:11205619 TDH -0.6 -5.27 -0.43 5.9e-7 Triglycerides; TGCT cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg13699009 chr12:122356056 WDR66 0.28 6.26 0.49 5.63e-9 Mean corpuscular volume; TGCT cis rs12478296 0.792 rs6740738 chr2:243007368 A/C cg06360820 chr2:242988706 NA -0.65 -5.29 -0.43 5.25e-7 Obesity-related traits; TGCT cis rs13326165 0.760 rs61150019 chr3:52354376 G/A cg27565382 chr3:53032988 SFMBT1 0.38 5.11 0.42 1.18e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs28595532 0.688 rs116173135 chr4:119721949 C/T cg21605333 chr4:119757512 SEC24D 1.72 8.99 0.63 3.52e-15 Cannabis dependence symptom count; TGCT cis rs10892173 0.566 rs12364667 chr11:117675286 A/C cg21640587 chr11:117668038 DSCAML1 0.71 8.26 0.6 1.87e-13 Myopia; TGCT cis rs3796352 0.892 rs58515094 chr3:52995575 C/T cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs78456975 1.000 rs10192959 chr2:1553393 G/T cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs3780378 0.875 rs7028112 chr9:5048814 G/A cg02405213 chr9:5042618 JAK2 -0.58 -7.5 -0.56 1.09e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg25660036 chr4:7070649 GRPEL1 -0.65 -5.46 -0.44 2.52e-7 Monocyte percentage of white cells; TGCT cis rs7072216 0.763 rs2274243 chr10:100175267 T/C cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs12368653 0.651 rs2307097 chr12:58195801 T/C cg12615879 chr12:58013172 SLC26A10 0.51 6.49 0.5 1.87e-9 Multiple sclerosis; TGCT cis rs7703051 0.585 rs918623 chr5:74596682 A/C cg00601450 chr5:74908170 NA 0.44 4.99 0.41 1.97e-6 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs1355023 0.547 rs7766562 chr6:106219028 A/G cg17356964 chr6:106582638 NA 0.25 4.57 0.38 1.18e-5 Age-related macular degeneration; TGCT cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg07061783 chr6:25882402 NA -0.47 -5.14 -0.42 1.02e-6 Blood metabolite levels; TGCT cis rs617219 0.710 rs2607141 chr5:78558635 G/T cg09550809 chr5:78407562 BHMT 0.37 5.24 0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1035144 0.505 rs11159479 chr14:81460651 C/T cg06600135 chr14:81408086 NA -0.48 -4.51 -0.38 1.48e-5 Male sexual orientation; TGCT trans rs877282 0.533 rs10904565 chr10:819991 G/T cg22713356 chr15:30763199 NA 0.88 6.61 0.51 1.01e-9 Uric acid levels; TGCT cis rs1215050 0.782 rs6532693 chr4:98655815 T/C cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg12667521 chr19:29218732 NA 0.53 5.64 0.45 1.07e-7 Methadone dose in opioid dependence; TGCT cis rs1008375 1.000 rs2872958 chr4:17665032 A/G cg16339924 chr4:17578868 LAP3 0.55 4.73 0.39 5.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs950169 0.800 rs34302901 chr15:85110943 C/G cg17173187 chr15:85201210 NMB 0.48 5.02 0.41 1.75e-6 Schizophrenia; TGCT cis rs11190604 1.000 rs75063298 chr10:102213600 C/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs11864453 0.680 rs8047377 chr16:72148339 T/C cg14768367 chr16:72042858 DHODH 0.51 4.89 0.4 3.11e-6 Fibrinogen levels; TGCT cis rs2180341 1.000 rs9398838 chr6:127635285 C/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs9985766 1.000 rs61361070 chr4:151002365 G/A cg05926478 chr4:151174724 DCLK2 -0.24 -4.72 -0.39 6.32e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs736408 0.522 rs998909 chr3:52805093 A/G cg10802521 chr3:52805072 NEK4 -0.8 -9.8 -0.66 3.79e-17 Bipolar disorder; TGCT cis rs6867913 0.709 rs891987 chr5:141467196 A/T cg01311360 chr5:140792558 PCDHGA4;PCDHGA6;PCDHGA9;PCDHGA1;PCDHGA8;PCDHGA5;PCDHGB1;PCDHGB4;PCDHGA3;PCDHGA10;PCDHGA2;PCDHGB6;PCDHGA7;PCDHGB2;PCDHGB5;PCDHGB3 0.4 4.6 0.38 1.01e-5 Asthma; TGCT cis rs2370759 1.000 rs76467481 chr10:32610740 T/G cg01819863 chr10:32635814 EPC1 1.03 10.07 0.67 8.33e-18 Sexual dysfunction (female); TGCT trans rs7726839 1.000 rs7726839 chr5:618586 A/G cg25482853 chr8:67687455 SGK3 0.9 7.22 0.54 4.58e-11 Obesity-related traits; TGCT cis rs12701220 0.817 rs7798459 chr7:1087965 C/T cg07217954 chr7:1067459 C7orf50 -0.47 -4.6 -0.38 1.03e-5 Bronchopulmonary dysplasia; TGCT cis rs7666738 0.830 rs7661264 chr4:98961574 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6831352 0.879 rs17218003 chr4:100054723 G/C cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs2197308 0.765 rs11182434 chr12:37923968 C/A cg13010199 chr12:38710504 ALG10B 0.67 5.38 0.44 3.57e-7 Morning vs. evening chronotype; TGCT cis rs7208859 0.623 rs9911784 chr17:29124580 A/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs425277 0.606 rs451061 chr1:2075068 C/G cg03732007 chr1:2071316 PRKCZ 0.27 6.23 0.49 6.69e-9 Height; TGCT cis rs9926296 0.509 rs2159113 chr16:89832083 C/T cg02609749 chr16:89786786 C16orf7;ZNF276 0.31 4.67 0.39 7.85e-6 Vitiligo; TGCT cis rs597539 0.617 rs686348 chr11:68636996 A/G cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2073300 1.000 rs6137960 chr20:23442886 G/A cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs4906332 1.000 rs7155980 chr14:103922419 C/G cg26031613 chr14:104095156 KLC1 -0.53 -4.72 -0.39 6.2e-6 Coronary artery disease; TGCT cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs7769051 0.615 rs12209144 chr6:133191064 A/T cg22852734 chr6:133119734 C6orf192 1.1 6.06 0.48 1.5e-8 Type 2 diabetes nephropathy; TGCT cis rs2282802 0.685 rs12188849 chr5:139621570 G/A cg01081189 chr5:139537190 NA 0.29 5.22 0.42 7.43e-7 Intelligence (multi-trait analysis); TGCT cis rs9788333 0.788 rs35007728 chr13:21893221 G/C cg25811766 chr13:21894605 NA 0.27 5.0 0.41 1.91e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg03395511 chr6:291903 DUSP22 -0.7 -7.2 -0.54 4.99e-11 Menopause (age at onset); TGCT cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg10862848 chr6:42927986 GNMT -0.38 -4.68 -0.39 7.53e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7100689 0.646 rs7089003 chr10:82124155 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs1729951 0.575 rs1654925 chr3:136690391 C/T cg12473912 chr3:136751656 NA -0.39 -6.18 -0.49 8.36e-9 Neuroticism; TGCT cis rs10504229 0.636 rs72649123 chr8:58045789 A/T cg11062466 chr8:58055876 NA 0.34 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs6087990 0.735 rs6119946 chr20:31329704 A/G cg13636640 chr20:31349939 DNMT3B -0.96 -13.14 -0.76 3.01e-25 Ulcerative colitis; TGCT cis rs78707713 0.531 rs12411720 chr10:71192471 T/G cg12610070 chr10:71211762 TSPAN15 -0.57 -6.35 -0.5 3.69e-9 Venous thromboembolism; TGCT cis rs137603 0.644 rs137636 chr22:39722477 C/A cg17798944 chr22:39715225 SNORD43;RPL3 -0.65 -7.03 -0.53 1.25e-10 Primary biliary cholangitis; TGCT cis rs79149102 0.579 rs3812943 chr15:75312715 C/G cg09165964 chr15:75287851 SCAMP5 -1.04 -5.48 -0.44 2.28e-7 Lung cancer; TGCT cis rs6840360 0.593 rs4696287 chr4:152606723 C/T cg22705602 chr4:152727874 NA -0.33 -5.5 -0.44 2.09e-7 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs2184585 chr6:8474168 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs526231 0.575 rs66730942 chr5:102306779 G/C cg23492399 chr5:102201601 PAM -0.53 -4.56 -0.38 1.23e-5 Primary biliary cholangitis; TGCT cis rs651907 0.535 rs17412601 chr3:101499275 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.47 0.68 9.24e-19 Colorectal cancer; TGCT cis rs875971 1.000 rs1183245 chr7:65541185 C/T cg18876405 chr7:65276391 NA -0.35 -5.19 -0.42 8.26e-7 Aortic root size; TGCT cis rs10489202 0.683 rs2294817 chr1:168073601 C/A cg24449463 chr1:168025552 DCAF6 -0.52 -5.52 -0.44 1.9e-7 Schizophrenia; TGCT cis rs9430161 0.579 rs6694011 chr1:11036935 G/A cg27631724 chr1:11040367 C1orf127 0.54 6.28 0.49 5.3300000000000004e-09 Ewing sarcoma; TGCT cis rs28595532 0.920 rs114928651 chr4:119734194 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg10295955 chr4:187884368 NA -0.98 -15.16 -0.81 5.3e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs10465746 0.967 rs28567085 chr1:84428859 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.2 0.49 7.68e-9 Obesity-related traits; TGCT cis rs4654899 0.897 rs6679753 chr1:21066634 G/C cg01072550 chr1:21505969 NA -0.49 -7.85 -0.58 1.67e-12 Superior frontal gyrus grey matter volume; TGCT cis rs9527 0.571 rs10786715 chr10:104620735 G/C cg04362960 chr10:104952993 NT5C2 0.55 4.73 0.39 5.91e-6 Arsenic metabolism; TGCT cis rs7666738 0.830 rs7687958 chr4:99014495 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.800 rs4099846 chr15:84956894 C/G cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs7223966 1.000 rs55868506 chr17:61851686 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg04267008 chr7:1944627 MAD1L1 -0.36 -4.82 -0.4 4.03e-6 Bipolar disorder and schizophrenia; TGCT cis rs4073582 0.595 rs708471 chr11:65931008 A/G cg16950941 chr11:66035639 RAB1B 0.55 5.42 0.44 2.94e-7 Gout; TGCT cis rs8017423 1.000 rs11622075 chr14:90669894 G/T cg04374321 chr14:90722782 PSMC1 0.75 7.72 0.57 3.31e-12 Mortality in heart failure; TGCT cis rs7772486 0.790 rs7753092 chr6:146248863 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4654899 0.865 rs12119348 chr1:21484633 C/T cg01072550 chr1:21505969 NA -0.48 -7.14 -0.54 7.03e-11 Superior frontal gyrus grey matter volume; TGCT cis rs854765 0.663 rs3744115 chr17:17749822 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.73 -7.06 -0.54 1.04e-10 Total body bone mineral density; TGCT cis rs909674 0.662 rs2899318 chr22:39837625 A/G cg01416388 chr22:39784598 NA -0.72 -6.54 -0.51 1.47e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs208520 0.690 rs12208977 chr6:66725257 G/A cg07460842 chr6:66804631 NA 0.95 9.67 0.66 7.83e-17 Exhaled nitric oxide output; TGCT cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg13395646 chr4:1353034 KIAA1530 0.4 4.95 0.41 2.34e-6 Obesity-related traits; TGCT cis rs10791323 0.628 rs2851118 chr11:133705995 A/C cg15485101 chr11:133734466 NA 0.4 5.08 0.41 1.38e-6 Childhood ear infection; TGCT cis rs832540 0.695 rs702686 chr5:56201350 A/G cg20203395 chr5:56204925 C5orf35 -0.57 -5.27 -0.43 5.77e-7 Coronary artery disease; TGCT cis rs12220898 0.749 rs2377975 chr10:50481421 A/G cg09603381 chr10:49954066 WDFY4 0.39 4.48 0.37 1.68e-5 Inflammatory biomarkers; TGCT cis rs13108904 0.840 rs13106092 chr4:1257290 T/A cg00684032 chr4:1343700 KIAA1530 0.22 4.73 0.39 5.92e-6 Obesity-related traits; TGCT cis rs7192750 0.562 rs9934803 chr16:71981630 T/G cg06353428 chr16:71660113 MARVELD3 0.75 6.74 0.52 5.43e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs78456975 0.527 rs11886696 chr2:1567841 A/G cg01028140 chr2:1542097 TPO -0.35 -5.35 -0.43 4.04e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9291683 0.530 rs13115193 chr4:9982191 C/T cg00071950 chr4:10020882 SLC2A9 0.65 8.23 0.59 2.21e-13 Bone mineral density; TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg15687855 chr3:44754131 ZNF502 -0.53 -6.79 -0.52 4.2e-10 Depressive symptoms; TGCT cis rs7647973 1.000 rs8897 chr3:49460407 A/G cg06212747 chr3:49208901 KLHDC8B 0.53 4.44 0.37 1.98e-5 Menarche (age at onset); TGCT cis rs2033711 0.936 rs893185 chr19:58989495 A/C cg04608855 chr19:58913158 NA 0.53 4.83 0.4 3.94e-6 Uric acid clearance; TGCT cis rs6933660 0.720 rs6913515 chr6:151753470 G/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.51 -4.57 -0.38 1.14e-5 Menarche (age at onset); TGCT cis rs1570884 0.857 rs4942848 chr13:50141345 A/G cg08779649 chr13:50194554 NA -0.3 -4.74 -0.39 5.87e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg03806693 chr22:41940476 POLR3H -1.05 -10.61 -0.69 4.09e-19 Vitiligo; TGCT trans rs877282 0.755 rs1769242 chr10:787896 T/C cg22713356 chr15:30763199 NA 0.95 8.14 0.59 3.51e-13 Uric acid levels; TGCT cis rs7017914 0.967 rs7013657 chr8:71637559 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs11190604 1.000 rs2495745 chr10:102329075 A/G cg23241863 chr10:102295624 HIF1AN 0.67 5.1 0.42 1.23e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7824557 0.564 rs2736290 chr8:11234298 C/T cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.09e-9 Retinal vascular caliber; TGCT cis rs1568889 0.938 rs12795971 chr11:28355104 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.61 0.61 2.72e-14 Bipolar disorder; TGCT trans rs7726839 0.540 rs55929359 chr5:595956 C/G cg25482853 chr8:67687455 SGK3 1.24 10.0 0.67 1.29e-17 Obesity-related traits; TGCT cis rs8014252 0.614 rs28612538 chr14:71025206 G/A cg11204974 chr14:71022665 NA -0.55 -4.66 -0.39 7.98e-6 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs899997 1.000 rs7182567 chr15:79045054 A/G cg00061860 chr15:78953028 NA -0.27 -4.51 -0.38 1.49e-5 Coronary artery disease or large artery stroke; TGCT cis rs7681440 0.835 rs6839608 chr4:90805493 T/C cg14346243 chr4:90757452 SNCA -0.5 -4.75 -0.39 5.46e-6 Dementia with Lewy bodies; TGCT cis rs6430585 0.941 rs10496737 chr2:136540083 A/G cg07169764 chr2:136633963 MCM6 0.89 7.96 0.58 9.17e-13 Corneal structure; TGCT cis rs4689388 0.853 rs1079216 chr4:6282473 T/C cg00701064 chr4:6280414 WFS1 0.39 4.79 0.4 4.7e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs909674 0.818 rs7364148 chr22:39842165 T/C cg24399712 chr22:39784796 NA -1.03 -10.67 -0.69 2.89e-19 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs7267979 1.000 rs2257420 chr20:25275890 C/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28595532 0.920 rs17323877 chr4:119671188 A/G cg21605333 chr4:119757512 SEC24D 1.33 7.24 0.55 4.06e-11 Cannabis dependence symptom count; TGCT cis rs4713118 0.666 rs4140646 chr6:27738801 G/A cg20933634 chr6:27740509 NA 0.35 4.83 0.4 3.92e-6 Parkinson's disease; TGCT cis rs1371867 0.846 rs1616833 chr8:101271821 C/T cg06002616 chr8:101225028 SPAG1 0.53 6.42 0.5 2.67e-9 Atrioventricular conduction; TGCT cis rs4319547 0.955 rs6489159 chr12:123112806 G/A cg05707623 chr12:122985044 ZCCHC8 -0.64 -4.88 -0.4 3.25e-6 Body mass index; TGCT cis rs9911578 0.967 rs72628392 chr17:56506160 A/G cg12560992 chr17:57184187 TRIM37 -0.76 -9.26 -0.64 7.61e-16 Intelligence (multi-trait analysis); TGCT cis rs801193 0.636 rs10233806 chr7:66118248 G/C cg18876405 chr7:65276391 NA -0.34 -4.98 -0.41 2.04e-6 Aortic root size; TGCT cis rs7617773 0.694 rs13099560 chr3:48204768 C/T cg11946769 chr3:48343235 NME6 -0.7 -6.55 -0.51 1.36e-9 Coronary artery disease; TGCT cis rs12510870 0.599 rs7665563 chr4:74452994 G/T cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs1075265 0.875 rs12616212 chr2:54266246 T/C cg15001959 chr2:54483431 TSPYL6;ACYP2 -0.18 -4.48 -0.37 1.7e-5 Morning vs. evening chronotype;Chronotype; TGCT cis rs7666738 0.830 rs4699597 chr4:99019031 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs72781680 1.000 rs72796329 chr2:24141912 G/A cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs4700695 0.719 rs27086 chr5:65453185 A/G cg21114390 chr5:65439923 SFRS12 -0.84 -7.33 -0.55 2.58e-11 Facial morphology (factor 19); TGCT cis rs6461049 0.765 rs4719432 chr7:2140330 A/G cg22963979 chr7:1858916 MAD1L1 -0.43 -7.13 -0.54 7.28e-11 Schizophrenia; TGCT cis rs2075371 0.966 rs1901204 chr7:133985896 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.39e-9 Mean platelet volume; TGCT trans rs10504390 0.656 rs75002270 chr8:66474587 T/C cg18118147 chr19:51128640 SYT3 -0.77 -6.81 -0.52 3.71e-10 IgG glycosylation; TGCT cis rs889312 0.500 rs832577 chr5:56163787 G/A cg24531977 chr5:56204891 C5orf35 -0.5 -5.09 -0.42 1.28e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs2956278 0.717 rs2956295 chr12:84677996 G/A cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs10489202 0.632 rs275137 chr1:168051266 A/C cg24449463 chr1:168025552 DCAF6 0.6 7.2 0.54 5.03e-11 Schizophrenia; TGCT cis rs2836974 0.563 rs997147 chr21:40695325 A/G cg11890956 chr21:40555474 PSMG1 -0.73 -6.6 -0.51 1.1e-9 Cognitive function; TGCT cis rs62244186 0.659 rs12108134 chr3:44543030 A/G cg10263370 chr3:44754102 ZNF502 0.38 4.43 0.37 2.01e-5 Depressive symptoms; TGCT cis rs896854 0.714 rs6471503 chr8:95990283 G/A cg09323728 chr8:95962352 TP53INP1 -0.48 -6.22 -0.49 7.08e-9 Type 2 diabetes; TGCT cis rs67478160 0.619 rs8018062 chr14:104281954 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.52 -0.51 1.61e-9 Schizophrenia; TGCT cis rs916888 0.779 rs430685 chr17:44859148 T/C cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7954584 0.567 rs11043246 chr12:122368944 G/A cg21016266 chr12:122356598 WDR66 0.52 6.57 0.51 1.27e-9 Mean corpuscular volume; TGCT cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs916888 0.647 rs199523 chr17:44848517 C/A cg15921436 chr17:44337874 NA -0.43 -6.49 -0.5 1.89e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11577318 0.537 rs12030833 chr1:26689220 A/G cg14210634 chr1:25870291 LDLRAP1 0.53 4.68 0.39 7.24e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9926296 0.632 rs7184315 chr16:89799373 C/G cg08627397 chr16:89984028 MC1R 0.31 4.98 0.41 2.05e-6 Vitiligo; TGCT cis rs6490294 0.718 rs11065976 chr12:112047571 T/C cg10833066 chr12:111807467 FAM109A 0.35 5.25 0.43 6.5e-7 Mean platelet volume; TGCT cis rs13191362 1.000 rs34177053 chr6:163007772 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3808502 0.605 rs11784572 chr8:11174484 C/G cg21775007 chr8:11205619 TDH -0.75 -7.62 -0.56 5.57e-12 Neuroticism; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg20007245 chr22:24372913 LOC391322 0.84 7.26 0.55 3.69e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9660992 0.710 rs1668873 chr1:205235990 G/A cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs6893300 0.542 rs7736300 chr5:179196898 G/A cg14593053 chr5:179126677 CANX 0.51 5.9 0.47 3.23e-8 Resting heart rate; TGCT cis rs2506155 0.752 rs17504012 chr10:33516355 G/C cg25928881 chr10:32632685 EPC1 0.31 4.65 0.39 8.31e-6 Migraine; TGCT cis rs3845702 0.736 rs6433821 chr2:180837806 T/A cg01881094 chr2:180872142 CWC22 -1.07 -6.88 -0.53 2.6e-10 Schizophrenia; TGCT cis rs12579753 1.000 rs12811607 chr12:82233619 T/G cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs6088580 0.602 rs6059834 chr20:33019299 A/G cg24642439 chr20:33292090 TP53INP2 0.49 4.51 0.38 1.5e-5 Glomerular filtration rate (creatinine); TGCT cis rs4808199 1.000 rs12977524 chr19:19568244 A/G cg03709012 chr19:19516395 GATAD2A 1.0 7.8 0.57 2.23e-12 Nonalcoholic fatty liver disease; TGCT cis rs858239 0.539 rs6461694 chr7:23187779 G/A cg05602783 chr7:23145260 KLHL7 -0.68 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs7923452 0.507 rs215494 chr10:30776589 T/G cg13289132 chr10:30722225 MAP3K8 -0.44 -5.23 -0.42 7.08e-7 Itch intensity from mosquito bite; TGCT cis rs4285028 0.747 rs9838301 chr3:121375144 G/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.93 -7.37 -0.55 2.07e-11 Multiple sclerosis; TGCT cis rs858239 0.600 rs28499396 chr7:23124098 A/G cg05602783 chr7:23145260 KLHL7 -0.6 -5.02 -0.41 1.76e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs933688 1.000 rs1363839 chr5:90671274 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.92 8.52 0.61 4.52e-14 Smoking behavior; TGCT cis rs9814567 0.727 rs4435681 chr3:134344435 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.67 -5.93 -0.47 2.86e-8 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs910316 0.934 rs4903278 chr14:75535019 C/A cg23033748 chr14:75592666 NEK9 0.28 4.7 0.39 6.7e-6 Height; TGCT cis rs7824557 0.737 rs10481445 chr8:11109269 T/C cg21775007 chr8:11205619 TDH -0.52 -4.54 -0.38 1.29e-5 Retinal vascular caliber; TGCT cis rs6540559 0.611 rs61747285 chr1:210004332 G/A cg22029157 chr1:209979665 IRF6 0.71 5.09 0.42 1.3e-6 Cleft lip with or without cleft palate; TGCT cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg25660036 chr4:7070649 GRPEL1 -0.67 -5.81 -0.46 4.85e-8 Monocyte percentage of white cells; TGCT cis rs3008870 0.755 rs2815381 chr1:67514591 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.81 7.56 0.56 7.97e-12 Lymphocyte percentage of white cells; TGCT cis rs2354432 0.607 rs1890039 chr1:146681951 T/C cg25205988 chr1:146714368 CHD1L 1.33 6.31 0.49 4.44e-9 Mitochondrial DNA levels; TGCT cis rs2456568 0.802 rs11020586 chr11:93638547 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2075371 0.897 rs1643102 chr7:133999983 T/A cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.12 14.24 0.79 7.22e-28 Height; TGCT cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.9 7.25 0.55 3.93e-11 Platelet count; TGCT cis rs858239 0.600 rs4628176 chr7:23142566 C/T cg05602783 chr7:23145260 KLHL7 -0.72 -6.15 -0.48 9.86e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs67311347 0.955 rs4974067 chr3:40374551 C/T cg17264618 chr3:40429014 ENTPD3 0.31 4.59 0.38 1.09e-5 Renal cell carcinoma; TGCT cis rs7727544 0.606 rs10058074 chr5:131686146 G/A cg14196790 chr5:131705035 SLC22A5 0.34 4.81 0.4 4.37e-6 Blood metabolite levels; TGCT cis rs11122272 0.735 rs2749707 chr1:231527316 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -6.23 -0.49 6.8e-9 Hemoglobin concentration; TGCT cis rs2663905 0.706 rs7162859 chr15:81360038 C/T cg09888468 chr15:81410853 NA 0.74 5.64 0.45 1.09e-7 QT interval (drug interaction); TGCT cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs57590327 0.503 rs7631052 chr3:81866235 C/A cg07356753 chr3:81810745 GBE1 -0.65 -5.97 -0.47 2.36e-8 Extraversion; TGCT cis rs9818758 0.607 rs66991555 chr3:49228643 A/G cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9517313 0.554 rs3809366 chr13:99230266 C/T cg07423050 chr13:99094983 FARP1 -0.23 -4.5 -0.37 1.53e-5 Neuroticism; TGCT cis rs11864453 0.647 rs9941346 chr16:72135707 C/G cg14768367 chr16:72042858 DHODH 0.52 5.27 0.43 5.78e-7 Fibrinogen levels; TGCT cis rs3784262 0.669 rs12148281 chr15:58311061 C/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.83e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs3820068 0.603 rs59475085 chr1:15911131 G/A cg05660106 chr1:15850417 CASP9 1.04 11.74 0.73 7.33e-22 Systolic blood pressure; TGCT cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg11644478 chr21:40555479 PSMG1 1.01 10.7 0.69 2.56e-19 Cognitive function; TGCT cis rs603424 0.551 rs646767 chr10:102084897 A/G cg22671421 chr10:102507979 PAX2 -0.54 -4.55 -0.38 1.26e-5 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs3027234 0.668 rs75664430 chr17:8064779 C/G cg08322244 chr17:8066669 VAMP2 -0.52 -4.99 -0.41 2.03e-6 Telomere length; TGCT cis rs7959452 0.527 rs4761157 chr12:69780907 A/G cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs769267 0.965 rs2905425 chr19:19475717 G/C cg08509172 chr19:19383838 TM6SF2 0.36 4.73 0.39 5.97e-6 Tonsillectomy; TGCT cis rs12497850 0.931 rs9311432 chr3:48850443 T/A cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs2456568 0.802 rs10765638 chr11:93636171 A/T cg16099599 chr11:93583650 C11orf90 -0.4 -4.98 -0.41 2.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10464366 0.544 rs953874 chr7:39147916 G/A cg15212455 chr7:39170539 POU6F2 0.3 6.48 0.5 1.91e-9 IgG glycosylation; TGCT cis rs6450176 1.000 rs10805455 chr5:53302302 T/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs11690935 0.959 rs1113389 chr2:172635365 C/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg20891558 chr2:74357851 NA 0.52 6.26 0.49 5.69e-9 Gestational age at birth (maternal effect); TGCT cis rs6674970 0.933 rs11204772 chr1:151056305 C/T cg00003202 chr1:151319512 RFX5 -0.51 -4.46 -0.37 1.84e-5 Childhood ear infection; TGCT cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs11690462 0.963 rs6731447 chr2:26590118 C/T cg11525280 chr2:26624667 C2orf39 0.37 4.52 0.38 1.4e-5 Coronary artery disease; TGCT cis rs2280018 0.526 rs2941257 chr16:15166445 T/C cg07549590 chr16:15018862 NA -0.3 -4.81 -0.4 4.28e-6 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs13256369 0.851 rs13255061 chr8:8563834 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs9916302 0.706 rs590051 chr17:37446571 T/C cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs651907 0.557 rs11720745 chr3:101441690 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.21 0.68 3.89e-18 Colorectal cancer; TGCT cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs4595586 1.000 rs1403521 chr12:39232007 A/G cg10518543 chr12:38710700 ALG10B 0.52 5.04 0.41 1.6e-6 Morning vs. evening chronotype; TGCT cis rs9457247 1.000 rs430097 chr6:167405073 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs6061231 0.556 rs6121571 chr20:60977323 T/G cg24112000 chr20:60950667 NA -0.38 -4.93 -0.4 2.55e-6 Colorectal cancer; TGCT cis rs2456568 0.548 rs6483280 chr11:93661592 T/C cg17595323 chr11:93583763 C11orf90 -0.44 -5.62 -0.45 1.21e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs921968 0.643 rs3931102 chr2:219520405 C/T cg02176678 chr2:219576539 TTLL4 0.4 5.85 0.47 4.03e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs2404602 0.598 rs71405204 chr15:76635305 C/G cg22467129 chr15:76604101 ETFA 0.48 4.83 0.4 3.99e-6 Blood metabolite levels; TGCT cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs2455799 0.613 rs9848007 chr3:15852593 T/A cg16303742 chr3:15540471 COLQ -0.24 -4.52 -0.38 1.43e-5 Mean platelet volume; TGCT trans rs7726839 0.540 rs28364691 chr5:664084 G/A cg25482853 chr8:67687455 SGK3 1.19 10.53 0.69 6.56e-19 Obesity-related traits; TGCT cis rs7086627 0.515 rs10887899 chr10:82210214 G/A cg01528321 chr10:82214614 TSPAN14 0.65 6.2 0.49 7.78e-9 Post bronchodilator FEV1; TGCT cis rs9500256 0.655 rs12208465 chr6:58330881 C/T cg16251399 chr6:58287822 GUSBL2 0.56 4.74 0.39 5.76e-6 Eosinophilic esophagitis (pediatric); TGCT cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.1 9.08 0.63 2.06e-15 Platelet count; TGCT cis rs6429082 0.818 rs453315 chr1:235680585 C/T cg26050004 chr1:235667680 B3GALNT2 0.58 5.07 0.41 1.43e-6 Adiposity; TGCT cis rs10949662 0.961 rs79566608 chr7:157530524 G/A cg14168080 chr7:157504135 PTPRN2 -0.39 -4.65 -0.39 8.24e-6 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg06873352 chr17:61820015 STRADA -0.52 -5.97 -0.47 2.31e-8 Prudent dietary pattern; TGCT cis rs617791 0.530 rs735942 chr11:65749337 A/G cg09783858 chr11:65769428 EIF1AD;BANF1 0.5 4.56 0.38 1.2e-5 Breast cancer; TGCT cis rs6952808 0.792 rs2056481 chr7:1955435 A/G cg22963979 chr7:1858916 MAD1L1 -0.37 -5.79 -0.46 5.33e-8 Bipolar disorder and schizophrenia; TGCT cis rs4665809 1.000 rs6709595 chr2:26259885 A/G cg22920501 chr2:26401640 FAM59B -0.71 -6.1 -0.48 1.27e-8 Gut microbiome composition (summer); TGCT cis rs2663905 0.611 rs1509560 chr15:81391713 T/G cg18837035 chr15:81426597 C15orf26 -0.6 -5.42 -0.44 2.98e-7 QT interval (drug interaction); TGCT cis rs826838 0.809 rs11169666 chr12:39211300 T/C cg26384229 chr12:38710491 ALG10B 0.94 8.31 0.6 1.42e-13 Heart rate; TGCT cis rs3096299 0.967 rs2911257 chr16:89484134 C/G cg06640241 chr16:89574553 SPG7 0.64 6.33 0.49 4.18e-9 Multiple myeloma (IgH translocation); TGCT cis rs9325144 0.602 rs7965838 chr12:38634365 A/T cg26384229 chr12:38710491 ALG10B -0.68 -5.99 -0.47 2.07e-8 Morning vs. evening chronotype; TGCT cis rs12188164 0.515 rs17562461 chr5:411361 C/T cg22025206 chr5:502436 SLC9A3 -0.26 -4.81 -0.4 4.32e-6 Cystic fibrosis severity; TGCT cis rs9534288 0.699 rs4280137 chr13:46664008 G/A cg15192986 chr13:46630673 CPB2 -0.5 -5.92 -0.47 2.92e-8 Blood protein levels; TGCT cis rs1669338 0.588 rs3931974 chr3:3186894 A/G cg16797762 chr3:3221439 CRBN 0.97 5.43 0.44 2.9e-7 White matter integrity; TGCT cis rs6831352 0.879 rs29001229 chr4:100046823 A/G cg12011299 chr4:100065546 ADH4 -0.43 -5.17 -0.42 9.06e-7 Alcohol dependence; TGCT cis rs826838 1.000 rs1393537 chr12:38920961 C/T cg13010199 chr12:38710504 ALG10B 0.77 6.38 0.5 3.21e-9 Heart rate; TGCT cis rs7975161 0.580 rs4246270 chr12:104728530 G/A cg25273343 chr12:104657179 TXNRD1 -0.36 -5.0 -0.41 1.9e-6 Toenail selenium levels; TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg24503407 chr1:205819492 PM20D1 0.52 6.92 0.53 2.13e-10 Monocyte percentage of white cells; TGCT cis rs2046867 0.818 rs17010215 chr3:72886965 A/G cg25664220 chr3:72788482 NA -0.57 -6.33 -0.49 4.08e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2296887 0.841 rs10883720 chr10:104010971 G/C cg26089160 chr10:104170217 PSD -0.61 -5.62 -0.45 1.19e-7 Parkinson's disease; TGCT cis rs66573146 1.000 rs7686168 chr4:6986057 C/A cg05069807 chr4:6945702 TBC1D14 0.35 4.94 0.41 2.51e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9868809 0.772 rs9877794 chr3:48718388 G/C cg00383909 chr3:49044727 WDR6 0.96 5.85 0.47 4.04e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7647973 0.626 rs2131108 chr3:49665390 C/T cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.58e-6 Menarche (age at onset); TGCT cis rs6840360 0.582 rs11732918 chr4:152319045 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.67e-9 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.764 rs55913633 chr4:119747444 C/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg20887711 chr4:1340912 KIAA1530 0.56 4.83 0.4 3.91e-6 Longevity; TGCT cis rs2153535 0.580 rs7450817 chr6:8481421 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg15242686 chr22:24348715 GSTTP1 0.39 5.24 0.43 6.81e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9952991 0.882 rs2847274 chr18:12777603 T/C cg24737193 chr18:12778029 NA 0.54 6.03 0.48 1.76e-8 Inflammatory skin disease; TGCT cis rs904251 0.561 rs1757189 chr6:37483727 G/C cg01843034 chr6:37503916 NA -0.54 -7.18 -0.54 5.74e-11 Cognitive performance; TGCT cis rs77633900 0.614 rs279997 chr15:76949262 T/C cg21673338 chr15:77095150 SCAPER -0.51 -4.83 -0.4 3.96e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs6088580 0.634 rs6059892 chr20:33105766 A/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs6589563 0.609 rs12292921 chr11:116621963 T/G cg01124546 chr11:117515332 DSCAML1 -0.44 -4.65 -0.39 8.28e-6 Eosinophil counts; TGCT cis rs11577318 0.853 rs7537477 chr1:26618829 C/T cg04990556 chr1:26633338 UBXN11 -0.6 -5.53 -0.45 1.78e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.24 0.43 6.6e-7 Height; TGCT cis rs116095464 0.558 rs112343653 chr5:257174 G/A cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs7949030 0.504 rs2516633 chr11:62371773 A/C cg13298116 chr11:62369859 EML3;MTA2 -0.59 -7.27 -0.55 3.49e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2153535 0.580 rs9406169 chr6:8509470 A/T cg07606381 chr6:8435919 SLC35B3 0.48 4.6 0.38 1.01e-5 Motion sickness; TGCT cis rs13118159 0.725 rs71614967 chr4:1341291 A/G cg13395646 chr4:1353034 KIAA1530 -0.41 -5.02 -0.41 1.75e-6 Longevity; TGCT cis rs769267 1.000 rs769267 chr19:19446936 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.69 6.01 0.47 1.94e-8 Tonsillectomy; TGCT cis rs2663905 0.611 rs1509559 chr15:81391411 G/A cg09888468 chr15:81410853 NA -0.64 -5.49 -0.44 2.16e-7 QT interval (drug interaction); TGCT cis rs4919694 1.000 rs10509760 chr10:104634107 A/G cg04362960 chr10:104952993 NT5C2 0.98 6.57 0.51 1.22e-9 Arsenic metabolism; TGCT cis rs62244186 0.627 rs3935212 chr3:44460954 G/A cg21672276 chr3:44754072 ZNF502 -0.41 -4.63 -0.38 9.16e-6 Depressive symptoms; TGCT cis rs12971120 0.891 rs3794953 chr18:72180519 C/T cg26446133 chr18:72167187 CNDP2 -0.35 -5.88 -0.47 3.53e-8 Refractive error; TGCT cis rs10892173 0.678 rs7122817 chr11:117657679 A/G cg21640587 chr11:117668038 DSCAML1 0.46 5.1 0.42 1.24e-6 Myopia; TGCT cis rs769267 0.965 rs2074296 chr19:19373689 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.69 6.05 0.48 1.57e-8 Tonsillectomy; TGCT cis rs2439831 0.867 rs6493082 chr15:43634808 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs11779988 0.545 rs404186 chr8:17795496 A/G cg01800426 chr8:17659068 MTUS1 -0.68 -5.41 -0.44 3.14e-7 Breast cancer; TGCT cis rs1865760 0.613 rs9379801 chr6:25901711 T/C cg03517284 chr6:25882590 NA -0.49 -5.07 -0.41 1.4e-6 Height; TGCT cis rs644799 0.965 rs566877 chr11:95528045 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9467711 0.591 rs36109883 chr6:26133070 G/A cg16898833 chr6:26189333 HIST1H4D 1.41 6.27 0.49 5.53e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs3733585 0.699 rs10017674 chr4:9967053 T/C cg00071950 chr4:10020882 SLC2A9 -0.57 -6.85 -0.52 3.12e-10 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs10174165 1.000 rs10174165 chr2:240441158 G/T cg04124606 chr8:142095021 NA 0.89 7.06 0.54 1.04e-10 Diisocyanate-induced asthma; TGCT cis rs6089829 0.962 rs6011544 chr20:61658782 T/C cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs11098499 0.954 rs56270433 chr4:120406030 C/T cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs6977660 0.714 rs10252597 chr7:19791171 G/T cg07541023 chr7:19748670 TWISTNB -0.85 -4.84 -0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs2180341 0.960 rs7766942 chr6:127691323 G/T cg24812749 chr6:127587940 RNF146 0.92 7.43 0.55 1.55e-11 Breast cancer; TGCT cis rs9902453 0.935 rs9905950 chr17:28431198 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.22 0.54 4.5e-11 Coffee consumption (cups per day); TGCT cis rs1799949 0.602 rs8176257 chr17:41216205 G/T cg05368731 chr17:41323189 NBR1 0.91 7.27 0.55 3.51e-11 Menopause (age at onset); TGCT cis rs7772486 0.875 rs6913797 chr6:146413758 A/G cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs9990220 0.586 rs12106673 chr3:112061731 G/A cg10677372 chr7:154003270 DPP6 -0.39 -6.72 -0.52 5.88e-10 Eosinophil percentage of white cells; TGCT cis rs559928 0.606 rs11231726 chr11:63987339 C/T cg02228329 chr11:64053129 BAD;GPR137 0.74 4.46 0.37 1.78e-5 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT trans rs6089829 1.000 rs6089828 chr20:61668998 C/T cg23505145 chr19:12996616 KLF1 0.88 9.67 0.66 8.02e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs2997447 0.761 rs79778025 chr1:26449337 A/G cg03844060 chr1:26490628 NA 0.28 4.61 0.38 9.87e-6 QRS complex (12-leadsum); TGCT cis rs6463523 0.864 rs73047957 chr7:759373 A/T cg14391382 chr7:866102 UNC84A 0.2 4.58 0.38 1.13e-5 Subjective well-being; TGCT cis rs5769765 0.817 rs8142561 chr22:50291750 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.91 0.47 3.12e-8 Schizophrenia; TGCT cis rs597539 0.652 rs514296 chr11:68654182 G/T cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.62e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17376456 0.542 rs6556833 chr5:93104707 T/C cg25358565 chr5:93447407 FAM172A 0.62 5.89 0.47 3.43e-8 Diabetic retinopathy; TGCT cis rs853679 0.517 rs55747925 chr6:28044337 T/C cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs7980687 0.657 rs10744151 chr12:123723735 G/C cg00376283 chr12:123451042 ABCB9 0.79 6.66 0.51 7.81e-10 Height;Educational attainment;Head circumference (infant); TGCT cis rs2742417 0.967 rs1609553 chr3:45735142 T/C cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT trans rs9388451 0.626 rs3734637 chr6:126081319 G/T cg05039488 chr6:79577232 IRAK1BP1 -0.84 -9.81 -0.66 3.58e-17 Brugada syndrome; TGCT cis rs477895 0.838 rs7111278 chr11:64016284 G/A cg23719950 chr11:63933701 MACROD1 -0.69 -5.74 -0.46 6.94e-8 Mean platelet volume; TGCT cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg02458000 chr6:26745757 NA 0.71 6.65 0.51 8.18e-10 Intelligence (multi-trait analysis); TGCT cis rs6598955 0.671 rs11247908 chr1:26638222 G/A cg04990556 chr1:26633338 UBXN11 0.67 5.44 0.44 2.77e-7 Obesity-related traits; TGCT cis rs4919694 1.000 rs112240253 chr10:104753726 C/T cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs2637266 0.905 rs34173296 chr10:78343389 C/T cg18941641 chr10:78392320 NA 0.42 5.45 0.44 2.62e-7 Pulmonary function; TGCT cis rs1129187 0.935 rs9462859 chr6:42946943 G/A cg13397359 chr6:42928475 GNMT 0.77 7.18 0.54 5.56e-11 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs36051895 0.659 rs7856912 chr9:5184449 G/A cg02405213 chr9:5042618 JAK2 -0.71 -8.93 -0.63 4.79e-15 Pediatric autoimmune diseases; TGCT cis rs9653442 0.545 rs2009095 chr2:100765081 C/T cg22139774 chr2:100720529 AFF3 -0.37 -5.78 -0.46 5.57e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10510102 0.688 rs76573813 chr10:123688470 G/T cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg12756686 chr19:29218302 NA 0.76 6.49 0.5 1.85e-9 Methadone dose in opioid dependence; TGCT trans rs1005277 0.579 rs9299760 chr10:38377920 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.39 0.6 9.23e-14 Extrinsic epigenetic age acceleration; TGCT cis rs11098499 0.644 rs17517414 chr4:120262101 G/C cg09307838 chr4:120376055 NA 0.55 5.36 0.43 3.98e-7 Corneal astigmatism; TGCT cis rs4653767 1.000 rs4653767 chr1:226916078 T/C cg11238820 chr1:226410871 MIXL1 0.33 4.47 0.37 1.77e-5 Parkinson's disease; TGCT cis rs12908161 0.920 rs35758837 chr15:85311382 C/T cg12863693 chr15:85201151 NMB 0.43 5.12 0.42 1.15e-6 Schizophrenia; TGCT cis rs344364 0.511 rs911391 chr16:1947016 C/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9811920 0.638 rs7629426 chr3:99652577 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 6.92 0.53 2.1e-10 Axial length; TGCT cis rs4972806 0.849 rs2113561 chr2:177030925 G/A cg14324370 chr2:177042789 NA 0.73 6.72 0.52 5.79e-10 IgG glycosylation; TGCT cis rs12579753 0.917 rs2401002 chr12:82215870 C/T cg07988820 chr12:82153109 PPFIA2 -0.58 -6.06 -0.48 1.52e-8 Resting heart rate; TGCT cis rs1552244 0.882 rs3732966 chr3:10015740 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs1799949 1.000 rs11651341 chr17:41428061 T/C cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs3796352 1.000 rs11720191 chr3:53013839 T/C cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8062405 0.965 rs62037363 chr16:28865042 T/C cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg02487422 chr3:49467188 NICN1 0.5 4.75 0.39 5.41e-6 Menarche (age at onset); TGCT cis rs12926788 0.640 rs12924246 chr16:24844629 A/G cg06028605 chr16:24865363 SLC5A11 0.42 4.63 0.38 9.1e-6 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2073300 1.000 rs6137959 chr20:23442640 T/C cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg16325326 chr1:53192061 ZYG11B -0.85 -11.92 -0.73 2.7e-22 Monocyte count; TGCT cis rs9409154 1.000 rs9409156 chr9:118209918 A/G cg14094498 chr9:119000864 PAPPA 0.23 4.59 0.38 1.05e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs514406 0.505 rs374662 chr1:53164549 C/A cg22166914 chr1:53195759 ZYG11B 0.44 7.66 0.57 4.64e-12 Monocyte count; TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs9611565 0.512 rs132784 chr22:42052363 G/A cg06481639 chr22:41940642 POLR3H 0.73 6.26 0.49 5.81e-9 Vitiligo; TGCT cis rs8017423 0.935 rs4643251 chr14:90669256 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -7.76 -0.57 2.65e-12 Mortality in heart failure; TGCT cis rs76419734 0.558 rs11721732 chr4:106521514 A/G cg24545054 chr4:106630052 GSTCD;INTS12 0.8 4.65 0.39 8.22e-6 Post bronchodilator FEV1; TGCT cis rs4975709 0.569 rs1684965 chr5:1865248 A/G cg07747251 chr5:1868357 NA 0.38 5.55 0.45 1.63e-7 Cardiovascular disease risk factors; TGCT cis rs1670533 0.932 rs4690214 chr4:1054636 T/C cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs3087591 0.887 rs12150521 chr17:29595108 C/T cg24425628 chr17:29625626 OMG;NF1 0.49 7.36 0.55 2.24e-11 Hip circumference; TGCT cis rs2836950 0.501 rs2836985 chr21:40701169 A/G cg06238570 chr21:40685208 BRWD1 -0.64 -6.56 -0.51 1.34e-9 Menarche (age at onset); TGCT cis rs7845219 0.544 rs7001535 chr8:95921090 C/G cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs6952808 0.792 rs11771973 chr7:1950440 C/G cg04267008 chr7:1944627 MAD1L1 -0.39 -5.2 -0.42 8.03e-7 Bipolar disorder and schizophrenia; TGCT trans rs1496653 0.602 rs13084870 chr3:23605117 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg10802521 chr3:52805072 NEK4 -0.65 -7.65 -0.57 4.72e-12 Electroencephalogram traits; TGCT cis rs782590 0.967 rs10496050 chr2:55806313 C/T cg18811423 chr2:55921094 PNPT1 0.65 6.93 0.53 2.02e-10 Metabolic syndrome; TGCT cis rs9640161 0.830 rs7800196 chr7:150061534 C/G cg21361702 chr7:150065534 REPIN1 0.54 5.14 0.42 1.04e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg03517284 chr6:25882590 NA 0.45 4.68 0.39 7.25e-6 Height; TGCT trans rs2243480 1.000 rs13237037 chr7:65997882 T/C cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs2180341 1.000 rs3798853 chr6:127636823 C/T cg27446573 chr6:127587934 RNF146 -1.1 -9.66 -0.66 8.66e-17 Breast cancer; TGCT cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs892864 0.554 rs3909897 chr5:127675355 C/G cg01939274 chr5:127874478 FBN2 -0.95 -4.53 -0.38 1.39e-5 Multiple system atrophy; TGCT cis rs7432375 0.523 rs12486911 chr3:136558953 C/G cg12473912 chr3:136751656 NA 0.33 4.62 0.38 9.59e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7944584 0.563 rs2280231 chr11:47600438 C/T cg20307385 chr11:47447363 PSMC3 0.9 8.49 0.61 5.41e-14 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs8177179 0.967 rs4994582 chr3:133437566 G/C cg24879335 chr3:133465180 TF 0.35 4.73 0.39 5.96e-6 Iron status biomarkers (transferrin levels); TGCT cis rs587847 0.597 rs4924162 chr15:37770365 A/G cg00216138 chr15:37171175 LOC145845 0.31 4.55 0.38 1.26e-5 Intraocular pressure; TGCT cis rs1570884 0.516 rs9316462 chr13:50176321 A/G cg03651054 chr13:50194643 NA 0.33 5.28 0.43 5.66e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs9527 0.590 rs12355120 chr10:104852166 T/G cg15744005 chr10:104629667 AS3MT -0.44 -5.12 -0.42 1.11e-6 Arsenic metabolism; TGCT cis rs12615966 1.000 rs17030284 chr2:105380921 A/G cg16465502 chr2:105461796 NA -0.77 -4.46 -0.37 1.83e-5 Pancreatic cancer; TGCT cis rs1480597 0.518 rs10736830 chr10:45208165 G/C cg12063947 chr10:45878068 ALOX5 0.26 4.44 0.37 2e-5 Parkinson's disease; TGCT cis rs10114408 0.918 rs10992943 chr9:96640493 G/A cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6570726 0.846 rs6570700 chr6:145931552 A/G cg05347473 chr6:146136440 FBXO30 0.5 4.6 0.38 1.04e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs3751972 0.590 rs12951895 chr17:26264497 C/G cg02948944 chr17:26242737 NA -0.46 -5.71 -0.46 7.8e-8 Fractional exhaled nitric oxide (childhood); TGCT cis rs921968 0.643 rs545779 chr2:219336108 A/G cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs56011263 0.687 rs4690293 chr4:706101 A/G cg20735989 chr4:730612 PCGF3 -0.25 -5.55 -0.45 1.65e-7 White blood cell count; TGCT cis rs7666738 0.546 rs7699578 chr4:98838893 T/C cg17366294 chr4:99064904 C4orf37 0.73 5.84 0.46 4.28e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1153858 1.000 rs12594857 chr15:45667178 A/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs112217694 1.000 rs75885777 chr4:104643130 C/T cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs6088590 0.561 rs6087600 chr20:33157217 T/C cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs4478858 0.735 rs6685728 chr1:31802550 T/C cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs12765878 0.603 rs1570221 chr10:105656874 G/A cg04788957 chr10:105438008 SH3PXD2A 0.29 4.44 0.37 2e-5 Coronary artery disease; TGCT cis rs6089829 0.643 rs6011545 chr20:61660038 G/A cg08564027 chr20:61660810 NA 0.29 4.57 0.38 1.17e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs17767294 0.708 rs72849205 chr6:28171529 C/T cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs36051895 0.589 rs4560849 chr9:5203866 C/G cg02405213 chr9:5042618 JAK2 -0.74 -9.28 -0.64 7.07e-16 Pediatric autoimmune diseases; TGCT cis rs35306767 0.903 rs11253492 chr10:936873 T/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs6424115 0.708 rs12755062 chr1:24185025 T/A cg15997130 chr1:24165203 NA -0.68 -6.7 -0.52 6.51e-10 Immature fraction of reticulocytes; TGCT cis rs4713118 0.591 rs2056924 chr6:27690174 G/A cg10876282 chr6:28092338 ZSCAN16 0.5 5.07 0.41 1.41e-6 Parkinson's disease; TGCT cis rs9303401 0.614 rs2333409 chr17:57139134 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.8 0.46 5.11e-8 Cognitive test performance; TGCT cis rs832540 0.593 rs252912 chr5:56195792 C/T cg12311346 chr5:56204834 C5orf35 -0.5 -4.79 -0.4 4.59e-6 Coronary artery disease; TGCT cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg11644478 chr21:40555479 PSMG1 -0.53 -4.57 -0.38 1.17e-5 Cognitive function; TGCT cis rs8051149 0.652 rs9926829 chr16:87883089 A/G cg01412419 chr16:87856264 NA -0.38 -4.62 -0.38 9.34e-6 Blood metabolite levels; TGCT cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.19 8.92 0.62 5.22e-15 Platelet count; TGCT cis rs7666738 0.830 rs10012167 chr4:99048579 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1034435 0.755 rs5768680 chr22:48892919 T/C cg05992904 chr22:48892994 FAM19A5 -0.34 -4.65 -0.39 8.37e-6 Late-onset Alzheimer's disease; TGCT cis rs2456568 0.867 rs7114457 chr11:93657817 C/T cg17595323 chr11:93583763 C11orf90 -0.45 -5.74 -0.46 6.75e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2688608 1.000 rs2688610 chr10:75654931 A/G cg19442545 chr10:75533431 FUT11 0.31 4.97 0.41 2.17e-6 Inflammatory bowel disease; TGCT cis rs79976124 0.877 rs79507557 chr6:66640908 C/A cg07460842 chr6:66804631 NA 0.57 5.09 0.42 1.26e-6 Type 2 diabetes; TGCT cis rs8180040 0.726 rs1869871 chr3:47023948 C/T cg27129171 chr3:47204927 SETD2 0.72 9.15 0.63 1.44e-15 Colorectal cancer; TGCT cis rs17331151 0.573 rs13080929 chr3:52885112 A/C cg15956490 chr3:53032818 SFMBT1 0.45 5.39 0.44 3.43e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs55962025 0.883 rs61792530 chr4:3145866 T/C cg06533319 chr4:3265114 C4orf44 0.22 4.5 0.37 1.54e-5 Parental longevity (mother's age at death); TGCT cis rs11105298 0.891 rs10858896 chr12:89920184 C/T cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4919694 1.000 rs17787717 chr10:104695699 T/G cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs2730260 0.537 rs73169233 chr7:158882201 C/T cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs9818758 0.607 rs4855860 chr3:49526044 A/T cg00383909 chr3:49044727 WDR6 -1.47 -6.42 -0.5 2.57e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs655601 0.643 rs112702671 chr5:180220930 C/T cg13724780 chr5:180237085 MGAT1 1.04 6.37 0.5 3.4e-9 Quantitative traits; TGCT cis rs12615966 1.000 rs17030309 chr2:105391328 G/A cg16465502 chr2:105461796 NA 0.79 5.07 0.41 1.42e-6 Pancreatic cancer; TGCT cis rs11190604 0.767 rs74869390 chr10:102189385 A/G cg16342193 chr10:102329863 NA -0.4 -5.02 -0.41 1.74e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3733631 1.000 rs10010631 chr4:104644543 A/G cg24090629 chr4:104641072 TACR3 -0.77 -6.29 -0.49 4.9e-9 Menarche (age at onset); TGCT cis rs4819052 1.000 rs28628220 chr21:46663741 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.77 6.05 0.48 1.56e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6754311 0.510 rs1374329 chr2:136421323 A/G cg07169764 chr2:136633963 MCM6 0.67 5.96 0.47 2.42e-8 Mosquito bite size; TGCT cis rs11190604 0.767 rs11190533 chr10:102190792 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.79 0.4 4.69e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4689388 0.856 rs1046314 chr4:6303955 A/G cg25554036 chr4:6271136 WFS1 -0.57 -8.07 -0.59 5.2e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9640161 0.830 rs35635199 chr7:150063342 C/T cg10018233 chr7:150070692 REPIN1 0.31 4.63 0.38 9.16e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs11785400 1.000 rs9720653 chr8:143731939 T/G cg10596483 chr8:143751796 JRK 0.54 5.77 0.46 5.95e-8 Schizophrenia; TGCT cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg10295955 chr4:187884368 NA -0.96 -13.89 -0.78 5e-27 Lobe attachment (rater-scored or self-reported); TGCT cis rs10791323 0.572 rs1114367 chr11:133737304 G/T cg03690763 chr11:133734501 NA -0.27 -4.53 -0.38 1.39e-5 Childhood ear infection; TGCT cis rs12541335 0.536 rs4266653 chr8:22169087 A/G cg09517075 chr8:22133004 PIWIL2 0.24 4.72 0.39 6.35e-6 Hypertriglyceridemia; TGCT cis rs9611565 0.840 rs3788584 chr22:41779073 T/A cg13695892 chr22:41940480 POLR3H -0.92 -9.32 -0.64 5.69e-16 Vitiligo; TGCT cis rs10504229 0.683 rs56235637 chr8:58106008 T/C cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs7178572 0.568 rs4886856 chr15:77510585 A/G cg15453836 chr15:77711506 NA -0.43 -4.82 -0.4 4.12e-6 Type 2 diabetes; TGCT cis rs7819412 0.512 rs1435282 chr8:11251705 G/A cg21775007 chr8:11205619 TDH -0.63 -6.66 -0.51 7.77e-10 Triglycerides; TGCT cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg17054783 chr10:134559939 INPP5A 0.23 4.48 0.37 1.64e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs346785 0.692 rs2279054 chr17:74287594 G/A cg09812376 chr17:74270190 QRICH2 -0.37 -5.54 -0.45 1.76e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs523522 0.924 rs11065150 chr12:120958875 T/G cg27279351 chr12:120934652 DYNLL1 0.77 6.58 0.51 1.18e-9 High light scatter reticulocyte count; TGCT cis rs2243480 1.000 rs462853 chr7:65558167 G/C cg18252515 chr7:66147081 NA -1.1 -7.18 -0.54 5.77e-11 Diabetic kidney disease; TGCT cis rs1801251 1.000 rs13035829 chr2:233604487 A/T cg25237894 chr2:233734115 C2orf82 0.31 5.62 0.45 1.21e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs13121766 chr4:98935766 A/C cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.559 rs6002408 chr22:41967870 C/T cg13695892 chr22:41940480 POLR3H -0.86 -7.99 -0.58 8.13e-13 Vitiligo; TGCT cis rs6582630 0.502 rs7311700 chr12:38463232 T/A cg13010199 chr12:38710504 ALG10B 0.64 5.09 0.42 1.27e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12477438 0.501 rs6542868 chr2:99782848 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs7178572 1.000 rs8024485 chr15:77718368 C/A cg22256960 chr15:77711686 NA -0.95 -10.93 -0.7 6.95e-20 Type 2 diabetes; TGCT cis rs933688 1.000 rs11959525 chr5:90703840 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 9.08 0.63 2.08e-15 Smoking behavior; TGCT cis rs13118159 0.550 rs28522910 chr4:1374774 C/T cg16405210 chr4:1374714 KIAA1530 -0.24 -4.47 -0.37 1.71e-5 Longevity; TGCT cis rs7666738 0.830 rs35213297 chr4:98984049 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7095607 0.813 rs10823143 chr10:69924903 T/A cg18986048 chr10:69913749 MYPN 0.48 5.51 0.44 2.03e-7 Lung function (FVC); TGCT cis rs7618915 0.501 rs9917834 chr3:52634619 A/C cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs11105298 0.891 rs11105299 chr12:89877943 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9902453 0.817 rs2628170 chr17:28056612 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.89 -0.53 2.55e-10 Coffee consumption (cups per day); TGCT cis rs6540559 0.546 rs74991018 chr1:210033790 T/G cg12034118 chr1:209979487 IRF6 0.65 4.56 0.38 1.2e-5 Cleft lip with or without cleft palate; TGCT cis rs2535633 0.631 rs9823697 chr3:53002150 A/G cg11645453 chr3:52864694 ITIH4 0.27 5.04 0.41 1.64e-6 Body mass index; TGCT cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.632 rs12349918 chr9:5125250 A/G cg02405213 chr9:5042618 JAK2 -0.71 -9.55 -0.65 1.57e-16 Pediatric autoimmune diseases; TGCT cis rs36051895 0.664 rs3780372 chr9:5097544 C/T cg02405213 chr9:5042618 JAK2 -0.76 -10.67 -0.69 3.05e-19 Pediatric autoimmune diseases; TGCT cis rs62064224 0.791 rs17806082 chr17:30705346 G/C cg18200150 chr17:30822561 MYO1D 0.58 7.69 0.57 3.92e-12 Schizophrenia; TGCT cis rs2235642 1.000 rs2235642 chr16:1584866 T/C cg07639376 chr16:1584516 IFT140;TMEM204 -0.32 -5.81 -0.46 5.02e-8 Coronary artery disease; TGCT cis rs3772130 0.962 rs9822949 chr3:121541239 T/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs6450176 1.000 rs67473746 chr5:53296730 G/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.12 -0.42 1.15e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs6684514 1.000 rs12027103 chr1:156244856 G/A cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs3096299 0.900 rs2911258 chr16:89480760 A/G cg02187348 chr16:89574699 SPG7 0.49 4.66 0.39 7.87e-6 Multiple myeloma (IgH translocation); TGCT cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg05665937 chr4:1216051 CTBP1 0.22 4.47 0.37 1.75e-5 Obesity-related traits; TGCT cis rs259282 0.605 rs3760937 chr19:33106893 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.56 5.12 0.42 1.11e-6 Schizophrenia; TGCT cis rs1775715 0.737 rs2799000 chr10:32124894 C/T cg14930904 chr10:32216787 ARHGAP12 0.53 5.11 0.42 1.16e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg03806693 chr22:41940476 POLR3H -1.15 -13.26 -0.77 1.52e-25 Vitiligo; TGCT cis rs12220898 0.749 rs7911514 chr10:50485523 T/G cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs4919044 0.808 rs55856996 chr10:94808618 T/G cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs6964587 1.000 rs12333563 chr7:91667326 G/A cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs7954584 0.531 rs10840631 chr12:122373729 C/T cg21016266 chr12:122356598 WDR66 0.53 6.62 0.51 9.84e-10 Mean corpuscular volume; TGCT cis rs6684514 0.922 rs12128785 chr1:156269389 A/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs478304 0.903 rs546202 chr11:65510024 C/T cg27068330 chr11:65405492 SIPA1 -0.74 -7.38 -0.55 1.95e-11 Acne (severe); TGCT cis rs6570726 0.791 rs400329 chr6:145879442 A/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs36051895 0.664 rs3780369 chr9:5095095 A/C cg02405213 chr9:5042618 JAK2 -0.72 -9.44 -0.65 2.89e-16 Pediatric autoimmune diseases; TGCT cis rs60843830 1.000 rs7605824 chr2:280819 A/G cg25945732 chr2:264204 ACP1;SH3YL1 -0.73 -7.29 -0.55 3.18e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9993613 0.778 rs6821492 chr4:73421616 G/T cg15102770 chr4:73434591 ADAMTS3 -0.5 -4.65 -0.39 8.51e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs12615966 1.000 rs55805894 chr2:105380420 A/T cg16465502 chr2:105461796 NA 0.78 5.03 0.41 1.66e-6 Pancreatic cancer; TGCT cis rs3617 0.573 rs6795646 chr3:52922621 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.73 -0.39 5.97e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs7698623 0.850 rs4693896 chr4:88797897 T/C cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs875971 0.964 rs55748098 chr7:65763618 T/C cg18876405 chr7:65276391 NA -0.34 -5.09 -0.42 1.27e-6 Aortic root size; TGCT cis rs7666738 0.830 rs13148363 chr4:98847498 T/C cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.79e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 0.583 rs2139190 chr15:76555539 G/C cg26408565 chr15:76604113 ETFA -0.46 -6.46 -0.5 2.15e-9 Blood metabolite levels; TGCT cis rs4891159 0.548 rs11150952 chr18:74128188 T/C cg24786174 chr18:74118243 ZNF516 0.67 12.93 0.76 9.47e-25 Longevity; TGCT cis rs4820539 1.000 rs13054985 chr22:23458577 G/A cg21100191 chr22:23484243 RTDR1 0.9 10.7 0.69 2.52e-19 Bone mineral density; TGCT cis rs13242816 1.000 rs17138708 chr7:116109062 T/G cg02799643 chr7:116139180 CAV2 -0.48 -5.45 -0.44 2.56e-7 P wave duration; TGCT cis rs7617773 0.780 rs13090538 chr3:48370769 A/C cg11946769 chr3:48343235 NME6 0.79 7.02 0.53 1.29e-10 Coronary artery disease; TGCT cis rs3540 0.574 rs8035980 chr15:90974390 C/G cg22089800 chr15:90895588 ZNF774 0.73 7.79 0.57 2.34e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg27535305 chr1:53392650 SCP2 -0.28 -5.93 -0.47 2.85e-8 Monocyte count; TGCT trans rs2070856 0.655 rs11699628 chr20:23703951 T/G cg13434034 chr8:135477110 NA 0.78 6.65 0.51 8.27e-10 Blood protein levels; TGCT cis rs75686122 0.892 rs4734076 chr8:104581641 A/G cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT trans rs7628219 0.607 rs10511008 chr3:70768256 A/T cg21160944 chr7:157584549 PTPRN2 0.6 6.82 0.52 3.58e-10 Insomnia (caffeine-induced); TGCT cis rs733175 0.857 rs751092 chr4:10005897 C/T cg00071950 chr4:10020882 SLC2A9 0.55 4.45 0.37 1.85e-5 Psychosis and Alzheimer's disease; TGCT cis rs6688613 0.685 rs6427047 chr1:166914258 A/G cg07049167 chr1:166818506 POGK 0.24 5.03 0.41 1.71e-6 Refractive astigmatism; TGCT cis rs9858542 0.953 rs6803222 chr3:49665976 T/G cg03060546 chr3:49711283 APEH -0.64 -5.7 -0.46 8.18e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs28595532 1.000 rs115965820 chr4:119586485 G/A cg11846333 chr4:119757529 SEC24D 0.92 5.05 0.41 1.54e-6 Cannabis dependence symptom count; TGCT cis rs9677476 1.000 rs6724253 chr2:232121998 A/G cg07929768 chr2:232055508 NA 0.3 4.44 0.37 1.97e-5 Food antigen IgG levels; TGCT cis rs853679 0.517 rs9380056 chr6:28104476 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs929354 0.629 rs6950739 chr7:156982450 T/C cg05182265 chr7:156933206 UBE3C -0.38 -8.2 -0.59 2.53e-13 Body mass index; TGCT cis rs11190604 1.000 rs10883506 chr10:102289743 C/G cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs597539 0.652 rs667989 chr11:68685776 T/A cg06112835 chr11:68658793 MRPL21 0.44 7.43 0.55 1.55e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs17685 0.753 rs4732542 chr7:75663203 A/G cg19862616 chr7:65841803 NCRNA00174 0.51 8.87 0.62 6.67e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7829975 0.660 rs10093926 chr8:8549020 A/C cg06636001 chr8:8085503 FLJ10661 -0.6 -5.02 -0.41 1.77e-6 Mood instability; TGCT cis rs17206232 0.534 rs16893787 chr5:64689014 A/G cg09571848 chr5:64330935 NA -0.31 -4.59 -0.38 1.05e-5 Schizophrenia; TGCT cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg13395646 chr4:1353034 KIAA1530 -0.36 -4.57 -0.38 1.17e-5 Obesity-related traits; TGCT cis rs2302045 1.000 rs2074823 chr2:242051503 C/A cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg03264133 chr6:25882463 NA 0.52 4.82 0.4 4.2e-6 Intelligence (multi-trait analysis); TGCT cis rs7172809 0.523 rs76675107 chr15:77552944 T/C cg22256960 chr15:77711686 NA -0.48 -4.67 -0.39 7.76e-6 Glucose homeostasis traits; TGCT cis rs259282 0.605 rs2302970 chr19:33098632 G/C cg26639809 chr19:33781782 NA 0.24 4.74 0.39 5.77e-6 Schizophrenia; TGCT cis rs2243480 0.901 rs35823062 chr7:65965821 A/G cg18252515 chr7:66147081 NA -1.22 -8.04 -0.59 6.02e-13 Diabetic kidney disease; TGCT cis rs2301573 1.000 rs12635414 chr3:129312981 G/A cg07730360 chr3:128845626 NA 0.5 5.81 0.46 5.04e-8 Hip circumference; TGCT cis rs2439831 0.867 rs2927072 chr15:43922398 T/C cg19166733 chr15:44192098 FRMD5 -0.24 -4.89 -0.4 3.08e-6 Lung cancer in ever smokers; TGCT cis rs6089829 0.962 rs3899032 chr20:61658542 G/A cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs1395 1.000 rs1659695 chr2:27406944 T/A cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.5 -6.75 -0.52 5.06e-10 Blood metabolite levels; TGCT cis rs3125734 0.633 rs1864836 chr10:64028538 C/G cg05499367 chr10:63213510 TMEM26 -0.33 -4.47 -0.37 1.77e-5 Rheumatoid arthritis; TGCT cis rs636291 0.510 rs1307487 chr1:10506667 G/A cg17425144 chr1:10567563 PEX14 0.5 7.06 0.54 1.04e-10 Prostate cancer; TGCT cis rs1997103 1.000 rs2177805 chr7:55404381 T/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs3772130 1.000 rs11721318 chr3:121429485 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.85 0.4 3.66e-6 Cognitive performance; TGCT cis rs7208859 0.623 rs216436 chr17:28922900 G/A cg13385521 chr17:29058706 SUZ12P 0.86 5.14 0.42 1.05e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2070488 0.804 rs13092164 chr3:38458533 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.79 7.95 0.58 9.74e-13 Electrocardiographic conduction measures; TGCT cis rs875971 0.862 rs7786892 chr7:65628876 G/A cg11764359 chr7:65958608 NA -0.56 -5.04 -0.41 1.61e-6 Aortic root size; TGCT cis rs17428076 0.514 rs3821095 chr2:172684006 A/G cg13550731 chr2:172543902 DYNC1I2 -0.59 -4.66 -0.39 8.07e-6 Myopia; TGCT cis rs6076065 0.748 rs2180139 chr20:23405281 G/A cg11657817 chr20:23433608 CST11 0.3 5.13 0.42 1.07e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs9341808 0.628 rs1892475 chr6:80862213 T/C cg08355045 chr6:80787529 NA 0.31 5.31 0.43 4.96e-7 Sitting height ratio; TGCT cis rs4654899 0.931 rs4654887 chr1:21234923 A/G cg01072550 chr1:21505969 NA 0.51 8.15 0.59 3.28e-13 Superior frontal gyrus grey matter volume; TGCT cis rs12052801 0.648 rs6734622 chr2:68350891 A/G cg00095431 chr2:67775781 NA -0.32 -4.46 -0.37 1.83e-5 Schizophrenia; TGCT cis rs2742417 0.603 rs2742455 chr3:45767116 A/G cg04837898 chr3:45731254 SACM1L -0.65 -6.95 -0.53 1.84e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9611519 0.780 rs2235850 chr22:41657626 C/T cg13695892 chr22:41940480 POLR3H -0.64 -6.05 -0.48 1.58e-8 Neuroticism; TGCT cis rs2280018 0.581 rs7404524 chr16:15129158 A/G cg07549590 chr16:15018862 NA -0.31 -4.68 -0.39 7.42e-6 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1552244 0.882 rs13099136 chr3:10031431 G/A cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg10108389 chr3:44770937 ZNF501 -0.48 -4.74 -0.39 5.68e-6 Depressive symptoms; TGCT cis rs4889855 0.614 rs9898443 chr17:78469357 C/T cg16591659 chr17:78472290 NA 0.36 5.66 0.45 1.01e-7 Fractional excretion of uric acid; TGCT cis rs10493773 1.000 rs10493774 chr1:86137963 A/G cg17807903 chr1:86174739 ZNHIT6 -0.36 -4.58 -0.38 1.11e-5 Urate levels in overweight individuals; TGCT cis rs1062177 1.000 rs12515762 chr5:151209922 G/T cg00977110 chr5:151150581 G3BP1 0.4 4.52 0.38 1.4e-5 Preschool internalizing problems; TGCT cis rs546131 0.928 rs558967 chr11:34827168 T/A cg11058730 chr11:34937778 PDHX;APIP 0.54 4.78 0.39 4.93e-6 Lung disease severity in cystic fibrosis; TGCT cis rs1670533 1.000 rs6852558 chr4:1059944 C/T cg27284194 chr4:1044797 NA 0.69 5.96 0.47 2.44e-8 Recombination rate (females); TGCT cis rs17152411 1.000 rs61873263 chr10:126589202 G/A cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs76419734 0.702 rs72673888 chr4:106808181 T/C cg24545054 chr4:106630052 GSTCD;INTS12 1.01 4.61 0.38 9.71e-6 Post bronchodilator FEV1; TGCT cis rs7666738 0.830 rs28852677 chr4:99039509 T/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.52 5.73 0.46 7.21e-8 Lymphocyte counts; TGCT cis rs8032315 1.000 rs6227 chr15:91425232 C/T cg05211768 chr15:91427848 FES 0.47 4.52 0.38 1.44e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs4788570 0.584 rs8051968 chr16:71761978 C/A cg06353428 chr16:71660113 MARVELD3 1.42 11.93 0.73 2.54e-22 Intelligence (multi-trait analysis); TGCT cis rs9993613 0.808 rs12645174 chr4:73431464 C/T cg15102770 chr4:73434591 ADAMTS3 0.51 4.57 0.38 1.16e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs793571 0.614 rs347117 chr15:59000957 C/T cg05156742 chr15:59063176 FAM63B 0.47 4.45 0.37 1.86e-5 Schizophrenia; TGCT cis rs116095464 0.510 rs73016876 chr5:244475 T/C cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.92e-10 Breast cancer; TGCT cis rs7119 0.651 rs12904208 chr15:77845911 C/T cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg12310025 chr6:25882481 NA -0.55 -5.58 -0.45 1.41e-7 Blood metabolite levels; TGCT cis rs9560113 1.000 rs9555804 chr13:112179751 T/C cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs17767294 0.708 rs78094982 chr6:27968350 G/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg26531700 chr6:26746687 NA 0.52 5.01 0.41 1.8e-6 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.576 rs246028 chr5:140333513 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9653442 0.564 rs7601892 chr2:100789490 G/A cg22139774 chr2:100720529 AFF3 -0.35 -5.55 -0.45 1.63e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7524258 0.903 rs4908608 chr1:7292772 T/C cg04342483 chr1:7259290 CAMTA1 -0.31 -4.56 -0.38 1.21e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs9650657 0.769 rs2116094 chr8:10598822 C/T cg27411982 chr8:10470053 RP1L1 -0.22 -4.79 -0.4 4.6e-6 Neuroticism; TGCT cis rs3806843 0.518 rs2569191 chr5:140013903 C/T cg19875535 chr5:140030758 IK -0.32 -5.19 -0.42 8.17e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs853679 0.517 rs9368552 chr6:28068426 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs669446 0.561 rs585652 chr1:44099910 T/C cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs1691799 0.899 rs1168302 chr12:66737518 C/T cg16791601 chr12:66731901 HELB -0.29 -6.38 -0.5 3.25e-9 White blood cell count (basophil); TGCT cis rs67072384 1.000 rs12272109 chr11:72453850 G/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs854765 0.522 rs63721860 chr17:17829576 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.6 0.56 6.32e-12 Total body bone mineral density; TGCT cis rs6460942 0.915 rs17444044 chr7:12458736 A/G cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs7412746 0.611 rs11204726 chr1:150743492 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs903263 0.601 rs10493750 chr1:84562265 C/T cg09664975 chr1:84543551 PRKACB -0.5 -4.86 -0.4 3.47e-6 Breast cancer (male); TGCT cis rs734999 0.588 rs2260976 chr1:2527678 A/G cg18854424 chr1:2615690 NA -0.46 -5.23 -0.43 6.92e-7 Ulcerative colitis; TGCT cis rs7833790 0.724 rs4739627 chr8:82734657 A/G cg17211192 chr8:82754475 SNX16 -0.95 -8.83 -0.62 8.45e-15 Diastolic blood pressure; TGCT cis rs7208859 0.673 rs11649765 chr17:29233888 T/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6964587 1.000 rs2282971 chr7:91584356 A/G cg22709100 chr7:91322751 NA 0.27 4.5 0.37 1.53e-5 Breast cancer; TGCT cis rs933688 1.000 rs10474353 chr5:90732285 A/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.97 8.61 0.61 2.82e-14 Smoking behavior; TGCT cis rs34779708 0.931 rs4007289 chr10:35269790 G/A cg04310649 chr10:35416472 CREM -0.51 -4.49 -0.37 1.6e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7917772 0.582 rs10786682 chr10:104318322 A/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.59 -5.73 -0.46 7.1e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9915657 0.595 rs10438697 chr17:70055734 A/G cg06234051 chr17:70120541 SOX9 0.23 5.07 0.41 1.41e-6 Thyroid hormone levels; TGCT cis rs6500602 0.627 rs863501 chr16:4588394 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.36 -5.23 -0.43 6.95e-7 Schizophrenia; TGCT cis rs694739 0.687 rs11231771 chr11:64140642 T/G cg23796481 chr11:64053134 BAD;GPR137 0.63 6.54 0.51 1.44e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs478304 0.934 rs610037 chr11:65546857 A/C cg17480646 chr11:65405466 SIPA1 0.4 4.95 0.41 2.42e-6 Acne (severe); TGCT cis rs1865760 0.566 rs3752419 chr6:26027433 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.76 7.33 0.55 2.58e-11 Height; TGCT cis rs892864 0.685 rs10063393 chr5:127745955 A/T cg01939274 chr5:127874478 FBN2 0.91 4.52 0.38 1.44e-5 Multiple system atrophy; TGCT cis rs67133203 0.632 rs829022 chr12:51374748 G/T cg01517968 chr12:52348879 ACVR1B -0.35 -4.52 -0.38 1.44e-5 Urinary tract infection frequency; TGCT cis rs6912958 0.500 rs9342104 chr6:87798512 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.54 -0.38 1.33e-5 Monocyte percentage of white cells; TGCT cis rs6840360 0.638 rs6816002 chr4:152589439 C/T cg22705602 chr4:152727874 NA -0.32 -5.45 -0.44 2.64e-7 Intelligence (multi-trait analysis); TGCT cis rs2180341 0.920 rs6906717 chr6:127596782 C/A cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs12449000 1 rs12449000 chr16:89872970 T/C cg26513180 chr16:89883248 FANCA 1.05 13.4 0.77 7.36e-26 Schizophrenia; TGCT cis rs7412746 0.634 rs12562939 chr1:150951452 A/C cg04414720 chr1:150670196 GOLPH3L 0.39 4.68 0.39 7.48e-6 Melanoma; TGCT cis rs2842992 0.747 rs9365095 chr6:160192928 T/G cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs6061231 0.631 rs2427317 chr20:60975725 C/T cg15674680 chr20:60982522 CABLES2 0.57 5.01 0.41 1.86e-6 Colorectal cancer; TGCT cis rs6674176 0.518 rs917294 chr1:44249485 A/G cg12908607 chr1:44402522 ARTN -0.64 -7.09 -0.54 8.92e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9303401 0.659 rs12946852 chr17:57013337 G/C cg25039879 chr17:56429692 SUPT4H1 0.52 4.57 0.38 1.15e-5 Cognitive test performance; TGCT cis rs6088590 0.687 rs73106933 chr20:33287425 T/C cg08999081 chr20:33150536 PIGU 0.27 5.04 0.41 1.61e-6 Coronary artery disease; TGCT cis rs3782455 1.000 rs76258123 chr12:114402449 G/C cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs3935685 0.874 rs4073356 chr15:78008430 C/T cg25212270 chr15:78015279 NA 0.25 5.45 0.44 2.66e-7 Intelligence (multi-trait analysis); TGCT cis rs13102973 0.965 rs13106621 chr4:135854975 A/T cg14419869 chr4:135874104 NA 0.23 4.58 0.38 1.12e-5 Subjective well-being; TGCT cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg00684032 chr4:1343700 KIAA1530 0.22 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs3905510 0.817 rs11750782 chr5:122976743 C/G cg15125798 chr5:122621645 NA 0.56 5.0 0.41 1.91e-6 Total body bone mineral density; TGCT cis rs7611238 0.560 rs7430205 chr3:195093242 A/T cg27323046 chr3:195102265 ACAP2 0.39 5.09 0.42 1.29e-6 Body mass index; TGCT cis rs769267 0.899 rs3934667 chr19:19431423 T/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.52 -0.51 1.57e-9 Tonsillectomy; TGCT trans rs6561151 0.718 rs11842000 chr13:44413467 T/C cg12856521 chr11:46389249 DGKZ 0.78 7.24 0.55 4.17e-11 Crohn's disease; TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg26516362 chr5:178986906 RUFY1 0.44 4.93 0.4 2.57e-6 Lung cancer; TGCT cis rs4727443 0.736 rs4727444 chr7:99614851 T/A cg13334819 chr7:99746414 C7orf59 0.56 4.71 0.39 6.63e-6 Interstitial lung disease; TGCT cis rs2180341 0.814 rs6940933 chr6:127732740 C/G cg24812749 chr6:127587940 RNF146 0.77 6.33 0.49 4.14e-9 Breast cancer; TGCT cis rs1348850 0.537 rs3770010 chr2:178537796 T/C cg22681709 chr2:178499509 PDE11A -0.49 -6.15 -0.48 9.86e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4819052 0.851 rs1999334 chr21:46670457 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 6.73 0.52 5.48e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12711979 0.875 rs11686157 chr2:3855020 C/G cg17052675 chr2:3827356 NA -0.32 -5.82 -0.46 4.77e-8 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg10295955 chr4:187884368 NA -1.02 -15.84 -0.82 1.42e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089584 0.854 rs6061407 chr20:60622048 A/C cg16423285 chr20:60520624 NA -0.6 -6.41 -0.5 2.76e-9 Body mass index; TGCT cis rs9467773 0.869 rs1796520 chr6:26410800 C/T cg26531700 chr6:26746687 NA -0.5 -4.81 -0.4 4.36e-6 Intelligence (multi-trait analysis); TGCT cis rs709400 0.628 rs11622356 chr14:103912195 C/T cg26031613 chr14:104095156 KLC1 0.88 9.75 0.66 5.05e-17 Body mass index; TGCT cis rs9926296 0.632 rs1800286 chr16:89869761 T/C cg04287289 chr16:89883240 FANCA 0.75 7.35 0.55 2.38e-11 Vitiligo; TGCT cis rs11785400 0.928 rs750529 chr8:143744877 G/C cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs1670533 1.000 rs10902752 chr4:1056199 C/T cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs7666738 0.830 rs6854994 chr4:98977624 C/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7043114 0.507 rs7856204 chr9:95173814 G/C cg13798575 chr9:95087839 CENPP;NOL8 -0.56 -5.61 -0.45 1.27e-7 Height; TGCT cis rs3806843 0.547 rs246054 chr5:140326159 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg15687855 chr3:44754131 ZNF502 -0.43 -5.27 -0.43 5.98e-7 Depressive symptoms; TGCT cis rs2153535 0.563 rs1737584 chr6:8536742 C/T cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7923609 0.967 rs10761751 chr10:65154885 A/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.15e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs1061377 0.965 rs7690465 chr4:39148635 G/T cg24403649 chr4:39172243 NA 0.2 4.55 0.38 1.26e-5 Uric acid levels; TGCT cis rs826838 1.000 rs11168367 chr12:38913397 T/G cg26384229 chr12:38710491 ALG10B 1.01 9.79 0.66 4.11e-17 Heart rate; TGCT cis rs2295359 1.000 rs11465753 chr1:67631423 T/C cg12940439 chr1:67600707 NA 0.54 5.62 0.45 1.22e-7 Psoriasis; TGCT cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg10117171 chr1:25599238 RHD -0.35 -5.73 -0.46 7.34e-8 Erythrocyte sedimentation rate; TGCT cis rs6882046 0.513 rs34320 chr5:88021527 T/G cg24804195 chr5:87968844 LOC645323 -0.57 -5.57 -0.45 1.5e-7 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs78487399 0.808 rs6708735 chr2:43731354 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.82 -0.4 4.03e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11247915 0.600 rs11247917 chr1:26655507 G/T cg25392287 chr1:26333318 NA 0.22 4.54 0.38 1.34e-5 Obesity-related traits; TGCT cis rs68170813 0.559 rs58319984 chr7:106965794 G/A cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg02675527 chr2:114030824 PAX8;LOC440839 0.49 6.43 0.5 2.46e-9 Lymphocyte counts; TGCT cis rs2749592 0.611 rs2505199 chr10:38392457 G/A cg25427524 chr10:38739819 LOC399744 -0.4 -6.97 -0.53 1.62e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs12216125 0.549 rs9358905 chr6:26077839 T/A cg17042849 chr6:26104293 HIST1H4C -0.66 -5.82 -0.46 4.73e-8 Iron status biomarkers; TGCT trans rs7698623 0.850 rs6532021 chr4:88769661 C/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs10540 0.686 rs12421266 chr11:537120 C/T cg03934478 chr11:495069 RNH1 0.32 4.55 0.38 1.28e-5 Body mass index; TGCT cis rs17761864 0.919 rs12452089 chr17:2135002 A/T cg02171503 chr17:1588363 PRPF8 -0.49 -4.86 -0.4 3.45e-6 Esophageal cancer (squamous cell); TGCT cis rs763014 0.898 rs8050792 chr16:656033 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.44 -0.6 7.14e-14 Height; TGCT cis rs13188771 0.527 rs365366 chr5:100877873 A/T cg10455971 chr5:101119566 NA 0.44 4.44 0.37 1.95e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs939658 0.805 rs11631590 chr15:79446199 C/T cg17916960 chr15:79447300 NA -0.51 -7.75 -0.57 2.89e-12 Refractive error; TGCT cis rs6570726 0.791 rs9373463 chr6:145894762 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7617773 0.817 rs6794644 chr3:48330037 T/C cg11946769 chr3:48343235 NME6 0.74 6.34 0.49 3.97e-9 Coronary artery disease; TGCT cis rs116095464 0.558 rs62346506 chr5:201594 T/C cg22857025 chr5:266934 NA -0.35 -6.52 -0.51 1.63e-9 Breast cancer; TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs9733 0.519 rs12095002 chr1:150649249 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs3733585 0.605 rs4235354 chr4:10122942 C/A cg00071950 chr4:10020882 SLC2A9 -0.51 -5.29 -0.43 5.33e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1218582 0.682 rs12046459 chr1:154912017 A/C cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 5.94e-9 Prostate cancer; TGCT cis rs6665290 0.904 rs1045285 chr1:227179054 G/A cg10327440 chr1:227177885 CDC42BPA -0.98 -19.72 -0.87 4.93e-40 Myeloid white cell count; TGCT cis rs11122272 0.735 rs2491412 chr1:231535880 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -6.18 -0.49 8.48e-9 Hemoglobin concentration; TGCT cis rs250677 0.687 rs185155 chr5:148455893 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs7666738 0.830 rs10516426 chr4:99035827 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6674970 1.000 rs6676190 chr1:151079317 C/T cg00003202 chr1:151319512 RFX5 -0.51 -4.46 -0.37 1.84e-5 Childhood ear infection; TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg24675658 chr1:53192096 ZYG11B -0.71 -7.87 -0.58 1.5e-12 Monocyte count; TGCT cis rs2688608 0.592 rs12253482 chr10:75496130 G/A cg23231163 chr10:75533350 FUT11 -0.28 -4.79 -0.4 4.71e-6 Inflammatory bowel disease; TGCT cis rs1461503 0.932 rs56778812 chr11:122840491 C/T cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs12048904 0.619 rs10783153 chr1:101328230 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.91 8.36 0.6 1.07e-13 Multiple sclerosis; TGCT cis rs7617773 0.780 rs7653336 chr3:48369464 T/A cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs12477438 1.000 rs57846982 chr2:99921574 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.98 -8.47 -0.61 6.09e-14 Chronic sinus infection; TGCT cis rs1218582 0.710 rs9794000 chr1:154878876 T/A cg09359103 chr1:154839909 KCNN3 -0.64 -11.6 -0.72 1.58e-21 Prostate cancer; TGCT cis rs2637266 1.000 rs7896379 chr10:78366247 C/T cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs6582630 0.504 rs4882367 chr12:38330878 A/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs7772486 0.754 rs1415747 chr6:146077249 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.41e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 0.920 rs56364904 chr4:119742504 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10992471 0.756 rs10123342 chr9:95087824 T/G cg14631576 chr9:95140430 CENPP -0.29 -4.69 -0.39 6.98e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7267979 1.000 rs2482931 chr20:25334445 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.25 0.49 6.11e-9 Schizophrenia; TGCT cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg20637647 chr7:64974828 NA 0.93 5.2 0.42 8.11e-7 Diabetic kidney disease; TGCT cis rs4319547 1.000 rs6489156 chr12:123100397 C/T cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.44 -0.44 2.68e-7 Body mass index; TGCT cis rs1008375 0.574 rs7670135 chr4:17566221 G/T cg16339924 chr4:17578868 LAP3 0.6 5.0 0.41 1.87e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4927850 1.000 rs10881563 chr3:195750225 A/G cg12923728 chr3:195709715 SDHAP1 -0.37 -7.53 -0.56 8.92e-12 Pancreatic cancer; TGCT cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.15e-6 Blood metabolite levels; TGCT cis rs1670533 1.000 rs652063 chr4:1084137 T/C cg20887711 chr4:1340912 KIAA1530 0.66 5.33 0.43 4.49e-7 Recombination rate (females); TGCT cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg22520471 chr17:61851767 DDX42;CCDC47 -0.53 -4.92 -0.4 2.7e-6 Prudent dietary pattern; TGCT trans rs1814175 0.817 rs4881658 chr11:49941123 G/A cg15704280 chr7:45808275 SEPT13 -0.7 -7.78 -0.57 2.45e-12 Height; TGCT cis rs2032447 0.867 rs9295683 chr6:26069495 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.58 -5.58 -0.45 1.47e-7 Intelligence (multi-trait analysis); TGCT cis rs453301 0.653 rs7016139 chr8:8895470 A/G cg06636001 chr8:8085503 FLJ10661 -0.77 -7.05 -0.53 1.09e-10 Joint mobility (Beighton score); TGCT cis rs1475911 0.744 rs12481958 chr21:43517269 A/G cg14562523 chr21:43528734 C21orf128;UMODL1 -0.25 -5.42 -0.44 2.94e-7 IgG glycosylation; TGCT cis rs7714584 1.000 rs79442859 chr5:150171210 T/C cg22134413 chr5:150180641 NA 1.11 7.3 0.55 3.05e-11 Crohn's disease; TGCT cis rs1403694 0.695 rs5029975 chr3:186436918 A/G cg12454167 chr3:186435060 KNG1 -0.51 -8.72 -0.62 1.49e-14 Blood protein levels; TGCT cis rs17401966 0.931 rs2185252 chr1:10415912 T/C cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs6964587 0.758 rs7798233 chr7:91500083 G/A cg17063962 chr7:91808500 NA -0.83 -6.71 -0.52 6.27e-10 Breast cancer; TGCT cis rs2535633 0.631 rs2336670 chr3:52998504 T/G cg11645453 chr3:52864694 ITIH4 -0.28 -4.94 -0.41 2.44e-6 Body mass index; TGCT cis rs4891159 0.790 rs683306 chr18:74112473 C/G cg24786174 chr18:74118243 ZNF516 -0.64 -10.12 -0.67 6.55e-18 Longevity; TGCT cis rs2204008 0.749 rs4579984 chr12:38166266 A/G cg13010199 chr12:38710504 ALG10B 0.6 4.8 0.4 4.57e-6 Bladder cancer; TGCT cis rs7833790 0.700 rs28390260 chr8:82769175 A/T cg27398817 chr8:82754497 SNX16 0.69 5.52 0.44 1.9e-7 Diastolic blood pressure; TGCT cis rs8180040 0.932 rs12489046 chr3:47527683 T/G cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs4653767 1.000 rs10916030 chr1:226919908 C/T cg10327440 chr1:227177885 CDC42BPA -0.47 -5.26 -0.43 6.06e-7 Parkinson's disease; TGCT cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg04546413 chr19:29218101 NA 0.84 6.82 0.52 3.52e-10 Methadone dose in opioid dependence; TGCT cis rs9467773 1.000 rs9461259 chr6:26504835 C/A cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT trans rs208520 0.526 rs9363522 chr6:66816642 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.08 -16.44 -0.83 5.98e-33 Exhaled nitric oxide output; TGCT cis rs9436747 0.667 rs7413823 chr1:66023716 A/G cg14976592 chr1:65886160 LEPROT;LEPR -0.56 -5.24 -0.43 6.6e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7666738 0.830 rs17027102 chr4:98919221 A/G cg17366294 chr4:99064904 C4orf37 -0.72 -7.32 -0.55 2.7e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs11105298 0.891 rs12369685 chr12:89928905 A/G cg00757033 chr12:89920650 WDR51B 0.29 4.46 0.37 1.78e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg24503407 chr1:205819492 PM20D1 0.61 8.72 0.62 1.52e-14 Menarche (age at onset); TGCT cis rs7178572 1.000 rs952471 chr15:77776498 C/G cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs753778 0.628 rs11579 chr8:142205132 G/A cg18755752 chr8:142205143 DENND3 -0.28 -5.08 -0.41 1.36e-6 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs5751150 1 rs5751150 chr22:42153292 T/G cg03806693 chr22:41940476 POLR3H 1.04 10.57 0.69 5.2e-19 Cannabis dependence symptom count; TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs367615 0.513 rs11741087 chr5:108807760 G/A cg17395555 chr5:108820864 NA 0.3 5.68 0.45 9.17e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1395 0.744 rs11126931 chr2:27474306 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs11578119 0.866 rs4623763 chr1:170349715 G/A cg09767346 chr1:170501363 GORAB 0.61 4.57 0.38 1.16e-5 Male-pattern baldness; TGCT trans rs7618501 1.000 rs9855505 chr3:49792158 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs12286929 0.687 rs6589485 chr11:115083875 G/A cg04017736 chr11:115827165 NA 0.19 4.63 0.38 9.21e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2115630 0.764 rs11073716 chr15:85335774 C/T cg11189052 chr15:85197271 WDR73 -0.58 -4.94 -0.41 2.45e-6 P wave terminal force; TGCT cis rs9926296 0.509 rs2159113 chr16:89832083 C/T cg03388025 chr16:89894329 SPIRE2 0.44 7.08 0.54 9.32e-11 Vitiligo; TGCT cis rs9549367 0.664 rs3794419 chr13:113851874 T/C cg18105134 chr13:113819100 PROZ -0.45 -7.84 -0.58 1.81e-12 Platelet distribution width; TGCT cis rs4722585 0.533 rs2158359 chr7:26193309 A/C cg07876897 chr7:26191696 NFE2L3 -0.41 -5.81 -0.46 4.96e-8 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs422249 0.512 rs174576 chr11:61603510 C/A cg19610905 chr11:61596333 FADS2 -0.96 -9.66 -0.66 8.51e-17 Trans fatty acid levels; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg23131131 chr22:24373011 LOC391322 -0.81 -8.78 -0.62 1.12e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs739496 0.579 rs7973309 chr12:112382251 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs10791097 0.592 rs7116068 chr11:130732739 A/C cg12179176 chr11:130786555 SNX19 -0.82 -10.21 -0.68 3.97e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs936229 0.813 rs8033381 chr15:75080685 G/A cg10253484 chr15:75165896 SCAMP2 -0.67 -5.38 -0.43 3.64e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs2455799 0.613 rs2470537 chr3:15716898 C/T cg16303742 chr3:15540471 COLQ -0.24 -4.56 -0.38 1.2e-5 Mean platelet volume; TGCT cis rs7412746 0.658 rs6669855 chr1:150861229 C/T cg04414720 chr1:150670196 GOLPH3L 0.4 4.87 0.4 3.35e-6 Melanoma; TGCT cis rs1048238 0.605 rs1889785 chr1:16348729 G/A cg22431228 chr1:16359049 CLCNKA -0.31 -6.72 -0.52 5.96e-10 Systolic blood pressure; TGCT cis rs61990749 0.544 rs12435761 chr14:78246077 C/G cg02301378 chr14:78227641 SNW1;C14orf178 0.61 4.52 0.38 1.43e-5 Fibroblast growth factor basic levels; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs909674 0.734 rs5757675 chr22:39838892 G/T cg01416388 chr22:39784598 NA -0.73 -6.89 -0.53 2.45e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4499344 0.768 rs10411319 chr19:33102805 C/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.81 8.62 0.61 2.57e-14 Mean platelet volume; TGCT cis rs1355223 0.583 rs2941044 chr11:34867444 A/C cg11058730 chr11:34937778 PDHX;APIP 0.75 8.24 0.59 2.05e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs892961 0.932 rs11650011 chr17:75412334 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.71 0.52 6.35e-10 Airflow obstruction; TGCT cis rs3540 0.553 rs2158406 chr15:90994499 T/C cg22089800 chr15:90895588 ZNF774 0.76 8.12 0.59 3.92e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7726839 0.540 rs58599998 chr5:596087 A/G cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs28595532 0.841 rs115080469 chr4:119720501 C/T cg14228332 chr4:119757509 SEC24D 1.3 6.62 0.51 9.91e-10 Cannabis dependence symptom count; TGCT cis rs1461503 0.900 rs1057704 chr11:122830274 T/C cg27398637 chr11:122830231 C11orf63 -0.41 -4.77 -0.39 5.14e-6 Menarche (age at onset); TGCT cis rs9913156 0.793 rs11568061 chr17:4546445 G/A cg19197139 chr17:4613644 ARRB2 0.85 7.91 0.58 1.19e-12 Lymphocyte counts; TGCT cis rs9443645 0.869 rs9443626 chr6:79629564 G/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg20607798 chr8:58055168 NA 0.49 4.52 0.38 1.43e-5 Developmental language disorder (linguistic errors); TGCT cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg05368731 chr17:41323189 NBR1 1.1 11.12 0.71 2.38e-20 Menopause (age at onset); TGCT cis rs2486288 0.656 rs12908818 chr15:45571668 A/G cg26924012 chr15:45694286 SPATA5L1 -0.78 -7.68 -0.57 4.17e-12 Glomerular filtration rate; TGCT cis rs4819052 0.851 rs875621 chr21:46682295 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.48 0.56 1.19e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10875746 0.903 rs989144 chr12:48483973 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs17102423 0.623 rs12100752 chr14:65611546 G/C cg11161011 chr14:65562177 MAX -0.4 -5.52 -0.44 1.89e-7 Obesity-related traits; TGCT cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg25036284 chr2:26402008 FAM59B -0.61 -4.9 -0.4 2.92e-6 Gut microbiome composition (summer); TGCT cis rs9534288 0.830 rs2897027 chr13:46636235 A/G cg15192986 chr13:46630673 CPB2 -0.52 -6.41 -0.5 2.82e-9 Blood protein levels; TGCT cis rs10504229 0.861 rs57314710 chr8:58196051 T/C cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT trans rs10953454 1.000 rs10272668 chr7:104494565 A/C cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs769267 0.930 rs2315022 chr19:19413381 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs12477438 0.501 rs11123770 chr2:99825102 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.68 6.37 0.5 3.39e-9 Chronic sinus infection; TGCT cis rs3796619 1.000 rs1453605 chr4:1075771 C/T cg27284194 chr4:1044797 NA 0.48 4.62 0.38 9.32e-6 Recombination rate (males); TGCT cis rs9902453 0.765 rs34585141 chr17:28336432 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs1371867 0.810 rs1618528 chr8:101259134 T/C cg06002616 chr8:101225028 SPAG1 0.57 6.77 0.52 4.48e-10 Atrioventricular conduction; TGCT cis rs854765 0.547 rs9913277 chr17:17919749 G/T cg09796270 chr17:17721594 SREBF1 0.25 5.03 0.41 1.71e-6 Total body bone mineral density; TGCT cis rs806215 0.547 rs3824003 chr7:127469624 C/T cg11539674 chr7:127291444 SND1 -0.35 -4.54 -0.38 1.33e-5 Type 2 diabetes; TGCT cis rs2439831 0.867 rs6493085 chr15:43654182 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs9372498 0.908 rs56255677 chr6:118695402 A/G cg18833306 chr6:118973337 C6orf204 -0.61 -4.81 -0.4 4.28e-6 Diastolic blood pressure; TGCT cis rs4642101 0.737 rs6767504 chr3:12826667 C/T cg05775895 chr3:12838266 CAND2 0.79 9.02 0.63 2.86e-15 QRS complex (12-leadsum); TGCT cis rs4237845 0.773 rs6650218 chr12:58289078 T/A cg02175503 chr12:58329896 NA 0.52 5.49 0.44 2.17e-7 Intelligence (multi-trait analysis); TGCT cis rs9467773 1.000 rs6910899 chr6:26524339 A/G cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs12541335 0.639 rs7834182 chr8:22163112 G/A cg26039829 chr8:22132926 PIWIL2 0.27 5.18 0.42 8.83e-7 Hypertriglyceridemia; TGCT cis rs11018874 0.597 rs4393275 chr11:89886397 C/T cg05041596 chr11:89867385 NAALAD2 0.51 5.29 0.43 5.4e-7 White blood cell types; TGCT cis rs644799 0.710 rs3748253 chr11:95519506 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.8 9.01 0.63 3.14e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7666738 0.830 rs10019087 chr4:99030211 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9650657 0.771 rs6601513 chr8:10594843 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.69 -0.39 6.99e-6 Neuroticism; TGCT cis rs1568889 0.877 rs1384903 chr11:28124359 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.8 6.46 0.5 2.2e-9 Bipolar disorder; TGCT cis rs3617 0.625 rs7617468 chr3:52849549 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.5 0.37 1.55e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs367943 1.000 rs348925 chr5:112817533 T/A cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs1505368 0.817 rs1283310 chr2:213273891 A/G cg16329650 chr2:213403929 ERBB4 0.64 6.07 0.48 1.43e-8 Symmetrical dimethylarginine levels; TGCT cis rs6089584 0.606 rs7270666 chr20:60577598 C/T cg06108461 chr20:60628389 TAF4 -0.41 -5.07 -0.41 1.43e-6 Body mass index; TGCT cis rs7267979 0.966 rs6037083 chr20:25290543 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs73110464 0.609 rs4919752 chr12:53359229 G/C cg25025879 chr12:53359317 NA -0.53 -5.78 -0.46 5.61e-8 Cancer (pleiotropy); TGCT cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg12310025 chr6:25882481 NA -0.67 -5.84 -0.46 4.3e-8 Intelligence (multi-trait analysis); TGCT cis rs3796619 1.000 rs4974638 chr4:1099201 G/A cg27284194 chr4:1044797 NA 0.47 4.57 0.38 1.17e-5 Recombination rate (males); TGCT cis rs11190604 1.000 rs3750719 chr10:102248950 C/G cg23241863 chr10:102295624 HIF1AN 0.61 4.62 0.38 9.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT trans rs1814175 0.817 rs10839318 chr11:49657511 G/C cg11707556 chr5:10655725 ANKRD33B -0.38 -7.79 -0.57 2.3e-12 Height; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg05457628 chr5:178986728 RUFY1 -0.52 -5.96 -0.47 2.42e-8 Lung cancer; TGCT cis rs61990749 0.597 rs759808 chr14:78250845 T/G cg02301378 chr14:78227641 SNW1;C14orf178 0.61 4.52 0.38 1.43e-5 Fibroblast growth factor basic levels; TGCT cis rs4523957 0.583 rs903159 chr17:2055109 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.69e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg10547057 chr6:26987810 LOC100270746;C6orf41 0.45 4.68 0.39 7.24e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs921968 0.643 rs524012 chr2:219433273 T/G cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs3806843 1.000 rs11167600 chr5:140174865 G/C cg19875535 chr5:140030758 IK 0.36 6.11 0.48 1.21e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs231513 0.556 rs7212487 chr17:42013499 A/T cg26893861 chr17:41843967 DUSP3 0.58 4.51 0.38 1.5e-5 Cognitive function; TGCT cis rs3617 0.539 rs12629687 chr3:52950659 T/C cg10802521 chr3:52805072 NEK4 0.58 6.69 0.51 6.85e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs2816062 0.786 rs2745317 chr1:18896552 G/A cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs4713118 0.662 rs149900 chr6:28014597 C/T cg12963246 chr6:28129442 ZNF389 0.49 4.84 0.4 3.82e-6 Parkinson's disease; TGCT cis rs7666738 0.687 rs6830176 chr4:99093955 G/C cg17366294 chr4:99064904 C4orf37 0.58 5.37 0.43 3.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.877 rs17316137 chr5:93456577 C/T cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs7044106 0.791 rs12554440 chr9:123485333 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.7 7.88 0.58 1.4e-12 Hip circumference adjusted for BMI; TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.48 0.56 1.19e-11 Prudent dietary pattern; TGCT cis rs2066819 1.000 rs74496027 chr12:56726340 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs2153535 0.580 rs9505448 chr6:8459804 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs6684514 0.922 rs12047994 chr1:156284535 C/A cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2404602 0.647 rs11852395 chr15:77087785 T/C cg22467129 chr15:76604101 ETFA 0.48 4.75 0.39 5.58e-6 Blood metabolite levels; TGCT cis rs1799949 0.965 rs8071278 chr17:41193910 A/T cg10047753 chr17:41438598 NA 0.64 5.75 0.46 6.45e-8 Menopause (age at onset); TGCT cis rs9942416 0.660 rs67803720 chr5:74984408 A/T cg19683494 chr5:74908142 NA 0.59 6.29 0.49 4.99e-9 Age-related disease endophenotypes; TGCT cis rs7439150 1.000 rs10050162 chr4:155478641 T/C cg22130008 chr4:155548532 NA -0.4 -5.08 -0.42 1.32e-6 Fibrinogen levels; TGCT cis rs11671005 0.695 rs8106061 chr19:58917990 G/C cg12042659 chr19:58951599 ZNF132 0.93 8.55 0.61 3.75e-14 Mean platelet volume; TGCT cis rs12693043 0.727 rs7562798 chr2:175434640 C/T cg11778734 chr2:175439522 WIPF1 -0.4 -5.17 -0.42 8.93e-7 Urate levels (BMI interaction); TGCT cis rs1568889 0.838 rs10835299 chr11:28277693 A/G cg06544937 chr11:28130018 METT5D1;KIF18A -0.9 -10.14 -0.67 5.63e-18 Bipolar disorder; TGCT cis rs2019137 0.936 rs2241978 chr2:113954006 A/G cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.53e-13 Lymphocyte counts; TGCT cis rs151997 0.649 rs152688 chr5:50211776 C/T cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs910316 0.737 rs175055 chr14:75488946 T/G cg08847533 chr14:75593920 NEK9 -0.84 -8.77 -0.62 1.16e-14 Height; TGCT cis rs7575217 0.643 rs2309996 chr2:101735838 T/G cg12737833 chr2:101500543 NPAS2 0.28 4.51 0.38 1.48e-5 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; TGCT cis rs7149242 0.922 rs9671394 chr14:101159674 C/T cg18089426 chr14:101175970 NA -0.47 -4.92 -0.4 2.68e-6 Platelet count; TGCT cis rs11148252 0.538 rs9535887 chr13:52730761 G/A cg00495681 chr13:53174319 NA 0.57 5.91 0.47 3.12e-8 Lewy body disease; TGCT cis rs7617773 0.817 rs3731555 chr3:48206102 G/A cg11946769 chr3:48343235 NME6 0.73 6.33 0.49 4.03e-9 Coronary artery disease; TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg25767906 chr1:53392781 SCP2 -0.52 -6.19 -0.49 8.06e-9 Monocyte count; TGCT cis rs11209185 0.509 rs9436356 chr1:68447202 A/G cg22082780 chr1:68452167 NA 0.31 4.84 0.4 3.86e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7651736 1.000 rs7651736 chr3:136760598 A/G cg12473912 chr3:136751656 NA 0.34 5.34 0.43 4.19e-7 Neuroticism; TGCT cis rs10540 1.000 rs12788729 chr11:502371 G/A cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs4665809 1.000 rs4665819 chr2:26309073 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs6087990 0.735 rs1855350 chr20:31387525 C/T cg13636640 chr20:31349939 DNMT3B 0.95 12.3 0.74 3.25e-23 Ulcerative colitis; TGCT trans rs208520 0.526 rs4710310 chr6:66802808 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.08 -15.68 -0.82 3.23e-31 Exhaled nitric oxide output; TGCT cis rs77972916 0.611 rs6709988 chr2:43601317 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.2 -0.49 7.52e-9 Granulocyte percentage of myeloid white cells; TGCT cis rs2882877 0.648 rs11694976 chr2:190377894 C/T cg10752008 chr2:190445175 SLC40A1 0.61 4.5 0.37 1.53e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs12220238 0.915 rs11000948 chr10:76031721 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.88 -5.95 -0.47 2.59e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7226408 0.857 rs72887017 chr18:34464233 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs10256972 0.786 rs3735686 chr7:1062527 G/A cg16145915 chr7:1198662 ZFAND2A -0.45 -5.44 -0.44 2.76e-7 Longevity;Endometriosis; TGCT cis rs12142240 0.698 rs13374893 chr1:46843800 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.79 -0.4 4.69e-6 Menopause (age at onset); TGCT cis rs909002 0.800 rs11589306 chr1:32082822 C/G cg11573219 chr1:32083031 HCRTR1 -0.44 -5.75 -0.46 6.6e-8 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.08e-9 Prudent dietary pattern; TGCT cis rs6988636 0.818 rs73339658 chr8:124173007 A/G cg23067535 chr8:124195133 FAM83A -0.34 -4.5 -0.37 1.57e-5 Urinary uromodulin levels; TGCT cis rs11190604 0.767 rs10748794 chr10:102175918 G/T cg16342193 chr10:102329863 NA 0.37 4.81 0.4 4.21e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7639513 0.590 rs3729931 chr3:12626516 A/G cg23032965 chr3:12705835 RAF1 -0.71 -7.49 -0.56 1.1e-11 Itch intensity from mosquito bite; TGCT cis rs11718455 0.960 rs11920021 chr3:44000856 T/C cg08738300 chr3:44038990 NA 0.85 6.41 0.5 2.72e-9 Coronary artery disease; TGCT cis rs7267979 0.903 rs6050482 chr20:25226327 C/T cg03522245 chr20:25566470 NINL 0.58 6.22 0.49 6.92e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7659604 0.539 rs11731917 chr4:122783233 G/A cg19748678 chr4:122722346 EXOSC9 0.88 8.76 0.62 1.21e-14 Type 2 diabetes; TGCT cis rs6933660 0.800 rs2046371 chr6:151754744 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.91 -9.69 -0.66 7.28e-17 Menarche (age at onset); TGCT cis rs73198271 0.740 rs10094270 chr8:8646633 G/A cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7666738 0.830 rs10049627 chr4:99025272 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11191419 1 rs11191419 chr10:104612335 T/A cg15744005 chr10:104629667 AS3MT -0.51 -6.51 -0.5 1.7e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10992471 0.756 rs1121979 chr9:95140218 G/A cg14631576 chr9:95140430 CENPP -0.3 -4.97 -0.41 2.21e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs317689 0.788 rs317679 chr12:69693172 A/C cg14784868 chr12:69753453 YEATS4 0.57 4.9 0.4 2.96e-6 Response to diuretic therapy; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.51 5.71 0.46 7.95e-8 Lymphocyte counts; TGCT cis rs7945705 0.747 rs2568045 chr11:9004060 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -4.95 -0.41 2.4e-6 Hemoglobin concentration; TGCT cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg25036284 chr2:26402008 FAM59B -0.66 -5.34 -0.43 4.22e-7 Gut microbiome composition (summer); TGCT cis rs9308731 0.966 rs36018702 chr2:111928373 G/T cg04202892 chr2:111875749 ACOXL -0.43 -4.74 -0.39 5.85e-6 Chronic lymphocytic leukemia; TGCT cis rs739496 0.527 rs2269801 chr12:112326123 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs116095464 0.558 rs10079760 chr5:230778 A/G cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs6998277 1.000 rs4281092 chr8:103647956 A/G cg10187029 chr8:103597600 NA -0.47 -6.1 -0.48 1.26e-8 Migraine; TGCT cis rs2295359 0.892 rs10889657 chr1:67615487 A/G cg12940439 chr1:67600707 NA 0.63 6.53 0.51 1.51e-9 Psoriasis; TGCT cis rs3764563 1.000 rs8107240 chr19:15737392 A/G cg20725493 chr19:15740067 CYP4F8 -0.43 -4.67 -0.39 7.75e-6 Inflammatory biomarkers; TGCT cis rs4237845 0.837 rs7963992 chr12:58295949 G/C cg02175503 chr12:58329896 NA 0.53 5.49 0.44 2.21e-7 Intelligence (multi-trait analysis); TGCT cis rs644799 0.511 rs1016030 chr11:95472693 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.66 6.29 0.49 5.03e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT cis rs6545883 0.965 rs6734830 chr2:61731112 G/A cg15711740 chr2:61764176 XPO1 -0.5 -4.51 -0.38 1.46e-5 Tuberculosis; TGCT cis rs4665809 0.759 rs62128394 chr2:26364026 T/G cg04944784 chr2:26401820 FAM59B 0.7 5.41 0.44 3.15e-7 Gut microbiome composition (summer); TGCT cis rs10193935 0.901 rs222478 chr2:42656919 G/T cg27598129 chr2:42591480 NA -0.32 -4.75 -0.39 5.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs172166 0.515 rs2622320 chr6:28115336 T/A cg13525197 chr6:28411240 ZSCAN23 -0.46 -4.5 -0.37 1.55e-5 Cardiac Troponin-T levels; TGCT cis rs13177918 0.677 rs3857421 chr5:149823147 C/T cg14059543 chr5:149831962 NA 0.71 10.06 0.67 9.14e-18 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7267979 0.966 rs4813557 chr20:25292545 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1215050 0.791 rs1585088 chr4:98675071 C/A cg17366294 chr4:99064904 C4orf37 -0.5 -5.2 -0.42 7.83e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg27535305 chr1:53392650 SCP2 -0.24 -4.73 -0.39 5.98e-6 Monocyte count; TGCT cis rs2742417 1.000 rs2742385 chr3:45756270 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.58e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7833790 0.963 rs6473312 chr8:82732515 C/A cg27398817 chr8:82754497 SNX16 -0.84 -6.06 -0.48 1.52e-8 Diastolic blood pressure; TGCT trans rs7726839 0.540 rs57306627 chr5:597643 T/C cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs12753569 0.837 rs1251490 chr1:76518693 T/C cg00791851 chr1:76518896 NA -0.34 -4.5 -0.37 1.52e-5 Personality dimensions; TGCT cis rs12497850 0.805 rs6446198 chr3:49007638 T/A cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 2.97e-7 Parkinson's disease; TGCT cis rs72615157 0.606 rs941288 chr7:99776808 G/A cg00814883 chr7:100076585 TSC22D4 -0.5 -4.86 -0.4 3.53e-6 Lung function (FEV1/FVC); TGCT cis rs6089829 0.925 rs2277767 chr20:61666937 G/A cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs7647973 0.559 rs9586 chr3:49213637 C/T cg07636037 chr3:49044803 WDR6 0.62 4.64 0.38 8.56e-6 Menarche (age at onset); TGCT cis rs6088580 0.634 rs11700221 chr20:32940320 T/C cg08999081 chr20:33150536 PIGU -0.27 -5.33 -0.43 4.46e-7 Glomerular filtration rate (creatinine); TGCT cis rs4803468 1.000 rs10422956 chr19:41901261 C/T cg09537434 chr19:41945824 ATP5SL -0.89 -10.09 -0.67 7.79e-18 Height; TGCT cis rs977747 0.872 rs11211479 chr1:47680978 T/C cg03885399 chr1:47691550 TAL1 -0.43 -5.58 -0.45 1.42e-7 Body mass index; TGCT cis rs2070488 0.965 rs2300668 chr3:38540541 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.81 -8.45 -0.6 6.55e-14 Electrocardiographic conduction measures; TGCT cis rs7917772 0.503 rs7914389 chr10:104295402 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10782582 0.593 rs11578480 chr1:76208989 T/G cg22875332 chr1:76189707 ACADM -0.49 -5.39 -0.44 3.35e-7 Daytime sleep phenotypes; TGCT cis rs6087771 0.714 rs6058259 chr20:30235302 A/G cg13852791 chr20:30311386 BCL2L1 0.8 7.08 0.54 9.22e-11 Subcortical brain region volumes;Putamen volume; TGCT cis rs10207060 0.771 rs4852124 chr2:240680022 C/T cg07506560 chr2:240697449 NA 0.6 8.04 0.59 6.17e-13 Obesity-related traits; TGCT cis rs7674212 0.512 rs2720462 chr4:104056210 T/G cg16532752 chr4:104119610 CENPE -0.61 -5.58 -0.45 1.44e-7 Type 2 diabetes; TGCT cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg21191810 chr6:118973309 C6orf204 -0.36 -4.74 -0.39 5.8e-6 Diastolic blood pressure; TGCT cis rs17270561 1.000 rs12200962 chr6:25828986 T/C cg16482183 chr6:26056742 HIST1H1C 0.79 5.25 0.43 6.49e-7 Iron status biomarkers; TGCT cis rs7698623 0.850 rs1477604 chr4:88771060 C/T cg27387453 chr4:88533842 DSPP -0.59 -4.48 -0.37 1.65e-5 Cardiovascular disease risk factors; TGCT cis rs4808199 0.947 rs10404728 chr19:19595014 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.2 0.42 8.14e-7 Nonalcoholic fatty liver disease; TGCT cis rs7511006 0.893 rs5771104 chr22:50651839 C/T cg08875078 chr22:50639485 SELO 0.54 5.1 0.42 1.21e-6 Obesity-related traits; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg10150615 chr22:24372951 LOC391322 -0.78 -7.5 -0.56 1.04e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg18765753 chr7:1198926 ZFAND2A 0.49 5.73 0.46 7.14e-8 Longevity;Endometriosis; TGCT cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9372498 0.505 rs62422247 chr6:118987559 G/T cg07617317 chr6:118971624 C6orf204 0.49 5.15 0.42 9.91e-7 Diastolic blood pressure; TGCT cis rs6728642 1.000 rs116171118 chr2:97695036 C/A cg26665480 chr2:98280029 ACTR1B -0.96 -5.36 -0.43 3.91e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs7267979 1.000 rs2257991 chr20:25270339 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11711311 1.000 rs4362695 chr3:113534856 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.67 -6.31 -0.49 4.49e-9 IgG glycosylation; TGCT cis rs3741404 0.868 rs595880 chr11:64006466 T/G cg03236948 chr11:63997492 DNAJC4 -0.36 -4.49 -0.37 1.6e-5 Platelet count; TGCT cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg13395646 chr4:1353034 KIAA1530 -0.48 -6.09 -0.48 1.34e-8 Obesity-related traits; TGCT cis rs1008375 0.966 rs3775924 chr4:17585984 T/C cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.830 rs28451101 chr4:99001190 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1696756 0.759 rs1298563 chr17:77834703 G/A cg00646381 chr17:77835854 NA 0.48 8.03 0.59 6.32e-13 Glucocorticoid-induced osteonecrosis (age 10 years and older); TGCT cis rs910316 1.000 rs4899544 chr14:75546556 C/T cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs17221829 0.764 rs6483020 chr11:89386384 A/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs151997 0.777 rs3846499 chr5:50254200 G/A cg06027927 chr5:50259733 NA 0.59 6.2 0.49 7.53e-9 Callous-unemotional behaviour; TGCT cis rs7959452 0.590 rs11177643 chr12:69785712 T/G cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs7769051 1.000 rs12204027 chr6:133122831 A/G cg22852734 chr6:133119734 C6orf192 1.22 6.9 0.53 2.34e-10 Type 2 diabetes nephropathy; TGCT cis rs7216064 0.773 rs74541577 chr17:65853651 C/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs4906332 1.000 rs2065017 chr14:103879579 T/C cg26031613 chr14:104095156 KLC1 -0.51 -4.63 -0.38 9.17e-6 Coronary artery disease; TGCT cis rs10504229 0.600 rs6987243 chr8:58115406 T/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.962 rs6089824 chr20:61659207 A/G cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs3858526 0.959 rs4559671 chr11:5923419 C/T cg05234568 chr11:5960015 NA -0.44 -4.6 -0.38 1.03e-5 DNA methylation (variation); TGCT cis rs2933343 0.700 rs2249514 chr3:128643812 C/T cg11901034 chr3:128598214 ACAD9 -0.65 -6.05 -0.48 1.55e-8 IgG glycosylation; TGCT cis rs968451 0.813 rs5757619 chr22:39724558 G/A cg17798944 chr22:39715225 SNORD43;RPL3 0.85 8.61 0.61 2.85e-14 Primary biliary cholangitis; TGCT cis rs1552244 0.882 rs3732966 chr3:10015740 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs909674 0.818 rs5757678 chr22:39843409 A/G cg24399712 chr22:39784796 NA 1.03 11.23 0.71 1.26e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9473924 0.542 rs56240592 chr6:50815514 T/A cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs7618915 1.000 rs3852063 chr3:52349204 A/G cg07507251 chr3:52567010 NT5DC2 0.46 6.07 0.48 1.44e-8 Bipolar disorder; TGCT cis rs6938 0.575 rs12909335 chr15:75214789 T/G cg10253484 chr15:75165896 SCAMP2 -0.58 -5.33 -0.43 4.48e-7 Breast cancer; TGCT cis rs1215050 0.791 rs165241 chr4:98681112 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.51 0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28595532 0.920 rs56331118 chr4:119767054 G/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs58950470 0.887 rs1784223 chr11:65380248 T/C cg27068330 chr11:65405492 SIPA1 0.59 5.23 0.42 7.07e-7 Schizophrenia; TGCT trans rs10506458 1.000 rs17763435 chr12:63416511 A/G cg22491629 chr6:157744540 C6orf35 0.98 8.47 0.61 6.02e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs7246657 0.943 rs10406177 chr19:37907947 G/A cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs8031584 0.678 rs4779497 chr15:31151365 T/A cg08704250 chr15:31115839 NA -0.43 -6.31 -0.49 4.47e-9 Huntington's disease progression; TGCT cis rs748404 0.690 rs2467737 chr15:43737188 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs57590327 0.528 rs11707026 chr3:81694044 C/A cg07356753 chr3:81810745 GBE1 -0.77 -6.91 -0.53 2.23e-10 Extraversion; TGCT cis rs9611519 0.602 rs8138520 chr22:41412928 A/G cg06634786 chr22:41940651 POLR3H -0.49 -4.54 -0.38 1.33e-5 Neuroticism; TGCT cis rs2180341 0.843 rs4895821 chr6:127572761 T/A cg27446573 chr6:127587934 RNF146 1.07 9.73 0.66 5.7e-17 Breast cancer; TGCT cis rs8077889 0.871 rs17675370 chr17:41900030 T/C cg26893861 chr17:41843967 DUSP3 1.08 12.97 0.76 7.86e-25 Triglycerides; TGCT cis rs77372450 0.515 rs2277948 chr5:157098233 T/C cg12606933 chr5:157078573 SOX30 -0.41 -4.65 -0.39 8.5e-6 Bipolar disorder (body mass index interaction); TGCT cis rs11674184 0.659 rs11679605 chr2:11722468 G/A cg07314298 chr2:11723111 GREB1 -0.4 -6.6 -0.51 1.08e-9 Endometriosis; TGCT cis rs7829975 0.742 rs1533059 chr8:8684953 A/G cg15556689 chr8:8085844 FLJ10661 -0.68 -6.44 -0.5 2.37e-9 Mood instability; TGCT cis rs603424 0.509 rs6584362 chr10:102087113 G/T cg22671421 chr10:102507979 PAX2 -0.54 -4.5 -0.37 1.53e-5 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs9921338 1.000 rs8049173 chr16:11436882 G/A cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.32e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs713587 0.713 rs62143001 chr2:25288675 G/A cg15423357 chr2:25149977 NA -0.6 -6.12 -0.48 1.15e-8 Body mass index in non-asthmatics; TGCT cis rs6831352 0.703 rs4235435 chr4:100039578 C/T cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs17076896 0.786 rs61956081 chr13:19933518 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT trans rs9388451 0.839 rs3757217 chr6:126069636 G/C cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.29 -0.6 1.61e-13 Brugada syndrome; TGCT trans rs1005277 0.563 rs2505216 chr10:38482830 T/C cg17830980 chr10:43048298 ZNF37B -0.84 -10.46 -0.68 9.38e-19 Extrinsic epigenetic age acceleration; TGCT cis rs9303401 0.538 rs2240258 chr17:56458183 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.56 5.21 0.42 7.76e-7 Cognitive test performance; TGCT cis rs2334880 0.678 rs34400718 chr16:71455852 G/A cg06353428 chr16:71660113 MARVELD3 -1.25 -8.07 -0.59 5.27e-13 Malaria; TGCT trans rs208520 0.690 rs12204512 chr6:66710486 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs6582630 0.502 rs10880092 chr12:38262965 A/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg16325326 chr1:53192061 ZYG11B 0.5 5.52 0.44 1.87e-7 Monocyte count; TGCT cis rs7119 0.604 rs2271397 chr15:77907775 T/C cg27398640 chr15:77910606 LINGO1 0.32 6.88 0.53 2.63e-10 Type 2 diabetes; TGCT cis rs12541335 0.639 rs68063696 chr8:22153236 A/G cg07298985 chr8:22133076 PIWIL2 0.33 5.0 0.41 1.91e-6 Hypertriglyceridemia; TGCT cis rs4776059 1.000 rs34431049 chr15:52940538 G/C cg25063058 chr15:52860530 ARPP19 0.51 4.57 0.38 1.18e-5 Schizophrenia; TGCT cis rs7568458 0.870 rs1009 chr2:85808737 A/G cg17127132 chr2:85788382 GGCX 0.67 6.24 0.49 6.43e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs62064224 0.818 rs35677406 chr17:30665005 T/C cg18200150 chr17:30822561 MYO1D 0.58 7.63 0.57 5.24e-12 Schizophrenia; TGCT cis rs12421382 0.507 rs10890995 chr11:109327622 A/G cg27471124 chr11:109292789 C11orf87 -0.51 -6.2 -0.49 7.73e-9 Schizophrenia; TGCT cis rs3617 0.591 rs11918800 chr3:52868145 G/A cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6951245 0.554 rs4724294 chr7:1139695 G/A cg23708337 chr7:1209742 NA 0.44 4.87 0.4 3.27e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12142240 0.738 rs17361749 chr1:46806480 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.95 0.47 2.58e-8 Menopause (age at onset); TGCT trans rs1908814 0.516 rs56102998 chr8:11796675 G/A cg15556689 chr8:8085844 FLJ10661 0.75 7.07 0.54 9.74e-11 Neuroticism; TGCT cis rs916888 0.821 rs199514 chr17:44856881 G/A cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.73e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg03517284 chr6:25882590 NA -0.65 -5.75 -0.46 6.49e-8 Intelligence (multi-trait analysis); TGCT cis rs4700695 0.614 rs37231 chr5:65218662 G/A cg21114390 chr5:65439923 SFRS12 0.64 4.61 0.38 9.9e-6 Facial morphology (factor 19); TGCT cis rs7572733 0.534 rs770657 chr2:198674184 C/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs9341808 0.718 rs35447745 chr6:80816748 T/C cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs1055129 0.682 rs7217432 chr17:73834604 A/G cg10935138 chr17:73851978 WBP2 0.51 4.46 0.37 1.79e-5 White matter hyperintensity burden; TGCT cis rs8177253 0.901 rs9843728 chr3:133501407 C/T cg20276088 chr3:133502917 NA -0.26 -5.39 -0.44 3.47e-7 Iron status biomarkers; TGCT cis rs9942416 0.660 rs4704234 chr5:75001432 A/G cg02573091 chr5:74908125 NA 0.45 5.17 0.42 9.3e-7 Age-related disease endophenotypes; TGCT trans rs1496653 0.602 rs35190363 chr3:23386880 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs6088580 0.634 rs6059866 chr20:33075810 A/C cg06115741 chr20:33292138 TP53INP2 0.51 4.5 0.37 1.56e-5 Glomerular filtration rate (creatinine); TGCT cis rs986417 0.818 rs1950311 chr14:60989604 A/C cg27398547 chr14:60952738 C14orf39 1.49 10.78 0.7 1.64e-19 Gut microbiota (bacterial taxa); TGCT cis rs7666738 0.830 rs6829567 chr4:99047340 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.931 rs6446253 chr3:48911443 C/T cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs8141529 0.702 rs132536 chr22:29302906 A/G cg02153584 chr22:29168773 CCDC117 -0.63 -4.92 -0.4 2.64e-6 Lymphocyte counts; TGCT cis rs9393777 0.513 rs9348728 chr6:26634436 G/A cg15659132 chr6:26577336 NA -0.77 -5.48 -0.44 2.26e-7 Intelligence (multi-trait analysis); TGCT cis rs950169 0.724 rs11632668 chr15:84948687 T/C cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs78545713 1.000 rs78661760 chr6:26250033 A/T cg12260798 chr6:26240519 HIST1H4F -0.54 -4.57 -0.38 1.16e-5 Iron status biomarkers (total iron binding capacity); TGCT cis rs477895 1.000 rs2286614 chr11:64068310 C/T cg23719950 chr11:63933701 MACROD1 -0.59 -4.63 -0.38 9.27e-6 Mean platelet volume; TGCT cis rs10927875 0.518 rs1763597 chr1:16343297 C/T cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs7582180 0.845 rs11683088 chr2:100920667 C/T cg14675211 chr2:100938903 LONRF2 0.46 4.52 0.38 1.43e-5 Intelligence (multi-trait analysis); TGCT cis rs1023500 0.573 rs4822088 chr22:42470589 G/C cg15557168 chr22:42548783 NA -0.22 -5.58 -0.45 1.47e-7 Schizophrenia; TGCT cis rs2439831 0.681 rs3742971 chr15:43622916 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.9 -6.84 -0.52 3.25e-10 Lung cancer in ever smokers; TGCT cis rs950027 0.549 rs2899375 chr15:45598335 G/A cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.86 -0.47 3.98e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs9487051 0.872 rs9487033 chr6:109605388 C/G cg01475377 chr6:109611718 NA 0.29 4.56 0.38 1.23e-5 Reticulocyte fraction of red cells; TGCT cis rs10791097 0.694 rs4937583 chr11:130741606 A/G cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4888262 0.526 rs7193423 chr16:74626340 A/C cg01733217 chr16:74700730 RFWD3 0.74 7.22 0.54 4.54e-11 Testicular germ cell tumor; TGCT cis rs2354432 0.607 rs6689243 chr1:146710559 A/T cg25205988 chr1:146714368 CHD1L -1.15 -4.8 -0.4 4.49e-6 Mitochondrial DNA levels; TGCT cis rs769267 0.965 rs4808937 chr19:19398005 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs10256972 0.521 rs871019 chr7:1105230 A/G cg18402987 chr7:1209562 NA 0.39 4.48 0.37 1.68e-5 Longevity;Endometriosis; TGCT cis rs4845570 1.000 rs11586946 chr1:151769806 G/A cg07092448 chr1:151763213 TDRKH -1.12 -8.71 -0.62 1.64e-14 Coronary artery disease; TGCT cis rs10479542 0.892 rs7723230 chr5:178980474 T/C cg00080972 chr5:178986291 RUFY1 0.46 5.38 0.44 3.5e-7 Lung cancer; TGCT cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg11890956 chr21:40555474 PSMG1 -0.76 -7.45 -0.56 1.36e-11 Cognitive function; TGCT trans rs1814175 0.817 rs1390676 chr11:50056778 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs10088262 0.629 rs9918907 chr8:124816862 A/G cg02993010 chr8:124780839 FAM91A1 -0.6 -4.61 -0.38 9.78e-6 Pancreatic cancer; TGCT cis rs2153535 0.580 rs969422 chr6:8451780 A/T cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs7666738 0.830 rs62318471 chr4:98925848 G/A cg17366294 chr4:99064904 C4orf37 0.72 7.19 0.54 5.3e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2013441 1.000 rs2703802 chr17:20101039 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs1865760 0.713 rs2013063 chr6:25994098 C/T cg17042849 chr6:26104293 HIST1H4C -0.55 -4.8 -0.4 4.4e-6 Height; TGCT cis rs1371867 0.875 rs1660320 chr8:101337579 A/C cg06636551 chr8:101224915 SPAG1 -0.45 -6.12 -0.48 1.13e-8 Atrioventricular conduction; TGCT cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg27286337 chr10:134555280 INPP5A 0.4 4.82 0.4 4.09e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs453301 0.571 rs2929452 chr8:9084465 G/A cg15556689 chr8:8085844 FLJ10661 -0.64 -6.05 -0.48 1.6e-8 Joint mobility (Beighton score); TGCT cis rs2832191 0.791 rs28633762 chr21:30500070 C/T cg08807101 chr21:30365312 RNF160 -0.62 -5.8 -0.46 5.14e-8 Dental caries; TGCT trans rs208520 1.000 rs12200490 chr6:66976084 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.86 7.83 0.58 1.88e-12 Exhaled nitric oxide output; TGCT cis rs7107174 0.901 rs990706 chr11:78135704 C/T cg12700464 chr11:78128424 GAB2 -0.68 -4.54 -0.38 1.33e-5 Testicular germ cell tumor; TGCT cis rs11578119 0.832 rs12131969 chr1:170352101 G/A cg09767346 chr1:170501363 GORAB 0.61 4.61 0.38 9.8e-6 Male-pattern baldness; TGCT cis rs1887596 0.705 rs2441067 chr13:27268653 A/G cg01312412 chr13:27282625 NA 0.27 4.83 0.4 3.96e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg24531977 chr5:56204891 C5orf35 -0.76 -7.66 -0.57 4.53e-12 Initial pursuit acceleration; TGCT cis rs853679 0.517 rs2275508 chr6:28094731 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg03609598 chr5:56110824 MAP3K1 -0.59 -4.87 -0.4 3.3e-6 Initial pursuit acceleration; TGCT cis rs3087591 1.000 rs7220268 chr17:29451910 T/C cg24425628 chr17:29625626 OMG;NF1 0.48 7.68 0.57 4.23e-12 Hip circumference; TGCT cis rs2486288 0.554 rs1719235 chr15:45576108 A/G cg26924012 chr15:45694286 SPATA5L1 -0.79 -8.17 -0.59 2.97e-13 Glomerular filtration rate; TGCT cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs3741404 0.868 rs595880 chr11:64006466 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.87 -9.49 -0.65 2.14e-16 Platelet count; TGCT cis rs7772486 0.875 rs6914813 chr6:146397798 A/G cg23711669 chr6:146136114 FBXO30 0.91 9.82 0.66 3.55e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7674212 0.531 rs6816370 chr4:103939433 C/T cg16532752 chr4:104119610 CENPE -0.59 -5.29 -0.43 5.43e-7 Type 2 diabetes; TGCT cis rs78487399 0.908 rs6717791 chr2:43822006 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3757318 0.540 rs17838427 chr6:151852039 G/A cg18745416 chr6:152011399 ESR1 0.52 4.84 0.4 3.82e-6 Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative);Breast cancer; TGCT cis rs597539 0.652 rs501799 chr11:68631240 G/T cg21862992 chr11:68658383 NA 0.46 6.64 0.51 8.64e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9926296 0.585 rs8058009 chr16:89856439 G/A cg21285383 chr16:89894308 SPIRE2 0.49 7.19 0.54 5.41e-11 Vitiligo; TGCT cis rs3858526 0.628 rs1840177 chr11:5944627 T/G cg02574844 chr11:5959923 NA 0.41 4.54 0.38 1.31e-5 DNA methylation (variation); TGCT cis rs7666738 0.830 rs7662218 chr4:98983126 T/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11676348 0.791 rs6726126 chr2:218952233 G/A cg00012203 chr2:219082015 ARPC2 -0.5 -4.63 -0.38 8.99e-6 Ulcerative colitis; TGCT cis rs1887596 0.705 rs2776435 chr13:27217535 T/C cg01312412 chr13:27282625 NA 0.28 4.92 0.4 2.69e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs6540559 0.673 rs6540561 chr1:209982255 C/T cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT cis rs4237845 0.844 rs4628718 chr12:58301600 A/C cg23860436 chr12:58378763 NA 0.35 4.97 0.41 2.16e-6 Intelligence (multi-trait analysis); TGCT cis rs34526934 0.608 rs13017511 chr2:177035395 A/G cg23561606 chr2:177418561 NA -0.44 -4.45 -0.37 1.91e-5 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs131777 0.563 rs5770927 chr22:51028945 C/T cg25309564 chr22:51001381 C22orf41 0.54 5.04 0.41 1.63e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9467711 1.000 rs9467708 chr6:26327956 T/C cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7829975 0.517 rs12542733 chr8:8824858 G/T cg15556689 chr8:8085844 FLJ10661 -0.76 -6.8 -0.52 3.85e-10 Mood instability; TGCT cis rs682748 1.000 rs682285 chr5:17149016 A/C cg23987134 chr5:17158319 LOC285696 -0.23 -5.42 -0.44 2.93e-7 Hippocampal atrophy; TGCT cis rs6933660 0.721 rs2128945 chr6:151767907 A/G cg17179660 chr6:151773299 C6orf211;RMND1 -0.55 -4.95 -0.41 2.37e-6 Menarche (age at onset); TGCT cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.65 -6.68 -0.51 7.09e-10 Intelligence (multi-trait analysis); TGCT cis rs7552404 1.000 rs211723 chr1:76103030 C/T cg03433033 chr1:76189801 ACADM -0.84 -10.0 -0.67 1.29e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg00786635 chr1:25594202 NA 0.52 5.56 0.45 1.59e-7 Erythrocyte sedimentation rate; TGCT cis rs67311347 0.544 rs7644643 chr3:40350209 C/T cg13683864 chr3:40499215 RPL14 0.8 7.48 0.56 1.18e-11 Renal cell carcinoma; TGCT cis rs453301 0.574 rs10081437 chr8:8948979 T/C cg06636001 chr8:8085503 FLJ10661 -0.61 -4.8 -0.4 4.49e-6 Joint mobility (Beighton score); TGCT cis rs9894429 1.000 rs35435780 chr17:79579602 G/T cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs1215050 0.765 rs1530905 chr4:98805705 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3096299 0.632 rs4399533 chr16:89539382 G/C cg08392591 chr16:89556376 ANKRD11 0.58 5.47 0.44 2.38e-7 Multiple myeloma (IgH translocation); TGCT cis rs2228479 0.718 rs62054253 chr16:89896932 T/C cg06558623 chr16:89946397 TCF25 0.55 4.77 0.39 5.13e-6 Skin colour saturation; TGCT cis rs12620999 0.941 rs7593758 chr2:237980920 G/T cg23555395 chr2:238036564 NA -0.27 -4.85 -0.4 3.69e-6 Systemic lupus erythematosus; TGCT cis rs780096 0.565 rs13022659 chr2:27743630 C/T cg12000995 chr2:27665139 KRTCAP3 -0.38 -4.53 -0.38 1.39e-5 Total body bone mineral density; TGCT cis rs28374715 0.532 rs316604 chr15:41775221 C/T cg18705301 chr15:41695430 NDUFAF1 -0.94 -17.29 -0.84 7.89e-35 Ulcerative colitis; TGCT cis rs9859260 0.614 rs493661 chr3:195786489 T/A cg02975922 chr3:195473998 MUC4 0.25 4.92 0.4 2.64e-6 Mean corpuscular volume; TGCT cis rs5769707 0.642 rs135880 chr22:50018654 T/A cg06623630 chr22:50017776 C22orf34 -0.27 -4.58 -0.38 1.11e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7192750 0.538 rs8054403 chr16:71990573 G/A cg06353428 chr16:71660113 MARVELD3 0.74 6.34 0.49 3.84e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs4076764 1.000 rs4076764 chr1:163441286 A/G cg24596788 chr1:163392923 NA -0.17 -4.99 -0.41 2.01e-6 Motion sickness; TGCT cis rs1799949 0.965 rs799910 chr17:41279561 G/C cg23758822 chr17:41437982 NA 0.67 6.8 0.52 3.96e-10 Menopause (age at onset); TGCT cis rs2404602 1.000 rs2896954 chr15:76851692 C/A cg22467129 chr15:76604101 ETFA -0.57 -6.54 -0.51 1.45e-9 Blood metabolite levels; TGCT cis rs4919694 1.000 rs77827514 chr10:104822009 C/T cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT cis rs2288884 1.000 rs2043298 chr19:52573067 A/C cg13540795 chr19:52551618 ZNF432 0.59 5.06 0.41 1.5e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs7772486 0.875 rs969694 chr6:146394655 A/G cg23711669 chr6:146136114 FBXO30 0.9 9.83 0.66 3.29e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2797160 0.547 rs1418645 chr6:125946476 T/A cg05901451 chr6:126070800 HEY2 -0.6 -5.02 -0.41 1.79e-6 Endometrial cancer; TGCT cis rs950169 0.922 rs4842941 chr15:84831312 G/C cg12863693 chr15:85201151 NMB -0.41 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT cis rs9419702 0.614 rs9419567 chr10:133535149 C/G cg20568497 chr10:133558893 NA 0.44 4.87 0.4 3.4e-6 Survival in rectal cancer; TGCT trans rs797680 0.891 rs9432453 chr1:93771629 G/A cg27528825 chr2:159282178 CCDC148 -0.34 -6.71 -0.52 6.19e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7914558 0.966 rs11191438 chr10:104637864 C/G cg05855489 chr10:104503620 C10orf26 0.51 4.6 0.38 1.02e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs114540395 0.925 rs76197608 chr10:103392896 T/C cg18276125 chr10:102749041 C10orf2 0.41 5.04 0.41 1.58e-6 Schizophrenia; TGCT cis rs57244997 1.000 rs73026573 chr6:162405119 C/T cg17173639 chr6:162384350 PARK2 -0.46 -5.07 -0.41 1.43e-6 Mosquito bite size; TGCT cis rs2299587 0.554 rs2073566 chr8:17743655 G/A cg01800426 chr8:17659068 MTUS1 -0.55 -4.96 -0.41 2.25e-6 Economic and political preferences; TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs9611565 0.592 rs5996037 chr22:41965292 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.25 -0.6 1.98e-13 Vitiligo; TGCT cis rs1857353 1.000 rs17096851 chr1:75888748 T/C cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT trans rs561341 0.943 rs508566 chr17:30289861 G/C cg20587970 chr11:113659929 NA -1.02 -10.68 -0.69 2.87e-19 Hip circumference adjusted for BMI; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.52 5.54 0.45 1.73e-7 Lymphocyte counts; TGCT cis rs2463822 1.000 rs2513744 chr11:62077785 C/A cg06239285 chr11:62104954 ASRGL1 0.88 5.78 0.46 5.64e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs1062177 0.826 rs2053063 chr5:151166764 T/C cg00977110 chr5:151150581 G3BP1 0.4 4.62 0.38 9.33e-6 Preschool internalizing problems; TGCT cis rs858239 0.509 rs6962213 chr7:23188109 G/A cg05602783 chr7:23145260 KLHL7 -0.59 -4.74 -0.39 5.69e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs748404 0.534 rs489509 chr15:43586907 T/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.78 0.39 4.86e-6 Lung cancer; TGCT cis rs4851266 1.000 rs12990462 chr2:100827216 G/A cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs17741873 0.836 rs17630952 chr10:75601414 T/A cg07699608 chr10:75541558 CHCHD1 0.69 4.87 0.4 3.27e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs7617773 0.539 rs17593974 chr3:48387334 G/T cg11946769 chr3:48343235 NME6 0.56 4.75 0.39 5.46e-6 Coronary artery disease; TGCT cis rs1153858 1.000 rs1365610 chr15:45694610 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs7267979 0.873 rs7453 chr20:25207074 A/G cg16686733 chr20:25566563 NINL 0.55 5.56 0.45 1.57e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1729951 0.575 rs361245 chr3:136695706 A/G cg12473912 chr3:136751656 NA 0.38 6.0 0.47 1.99e-8 Neuroticism; TGCT cis rs10875746 0.951 rs10875748 chr12:48526360 A/G cg20731937 chr12:48336164 NA 0.61 4.82 0.4 4.14e-6 Longevity (90 years and older); TGCT cis rs7589728 0.563 rs78168096 chr2:88473575 G/A cg04511125 chr2:88470314 THNSL2 0.63 4.98 0.41 2.04e-6 Plasma clusterin levels; TGCT cis rs910316 1.000 rs175443 chr14:75601963 C/T cg23033748 chr14:75592666 NEK9 -0.28 -4.84 -0.4 3.71e-6 Height; TGCT cis rs2832191 0.791 rs57721945 chr21:30498744 T/C cg24692254 chr21:30365293 RNF160 -0.86 -9.11 -0.63 1.83e-15 Dental caries; TGCT cis rs7698623 0.850 rs3886171 chr4:88800053 A/G cg02735620 chr4:88950514 PKD2 -0.44 -4.78 -0.39 4.95e-6 Cardiovascular disease risk factors; TGCT cis rs7829975 0.688 rs7827182 chr8:8380471 C/G cg08975724 chr8:8085496 FLJ10661 0.65 6.31 0.49 4.52e-9 Mood instability; TGCT cis rs1451375 0.698 rs68143668 chr7:50638110 C/T cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs2456568 0.803 rs10765642 chr11:93640355 C/T cg26875233 chr11:93583750 C11orf90 0.46 6.09 0.48 1.33e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9467711 0.651 rs7749414 chr6:26074884 G/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.6 -4.67 -0.39 7.83e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs769267 1.000 rs2285627 chr19:19467937 T/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.68 -5.97 -0.47 2.3e-8 Tonsillectomy; TGCT cis rs72945132 0.825 rs72947052 chr11:70188575 A/G cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg06481639 chr22:41940642 POLR3H 0.69 6.26 0.49 5.71e-9 Vitiligo; TGCT cis rs6733011 0.518 rs12992214 chr2:99466337 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.5 -4.81 -0.4 4.34e-6 Bipolar disorder; TGCT cis rs295140 0.803 rs4233994 chr2:201129211 G/C cg04283868 chr2:201171347 SPATS2L 0.52 5.2 0.42 8.14e-7 QT interval; TGCT cis rs10504229 0.871 rs10504226 chr8:58159283 A/G cg20607798 chr8:58055168 NA 0.44 4.45 0.37 1.9e-5 Developmental language disorder (linguistic errors); TGCT cis rs11024102 0.925 rs7127818 chr11:17004090 G/C cg15378786 chr11:17036137 PLEKHA7 0.48 4.44 0.37 1.95e-5 Glaucoma (primary angle closure); TGCT cis rs78487399 0.908 rs73925553 chr2:43810646 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4665809 1.000 rs2384322 chr2:26291146 C/G cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs3733585 0.654 rs4447863 chr4:9938969 T/C cg00071950 chr4:10020882 SLC2A9 -0.62 -7.46 -0.56 1.33e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2439831 0.681 rs528517 chr15:43612925 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.63 0.51 9.35e-10 Lung cancer in ever smokers; TGCT cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs9388451 0.807 rs1269175 chr6:126040435 A/G cg05901451 chr6:126070800 HEY2 1.01 12.34 0.74 2.52e-23 Brugada syndrome; TGCT cis rs7412746 0.634 rs12409208 chr1:150860055 A/G cg04414720 chr1:150670196 GOLPH3L 0.4 4.82 0.4 4.06e-6 Melanoma; TGCT cis rs739496 0.541 rs593226 chr12:111993886 A/G cg10833066 chr12:111807467 FAM109A 0.35 5.57 0.45 1.52e-7 Platelet count; TGCT cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs7659420 chr4:98878714 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.921 rs5751077 chr22:41720728 G/C cg06634786 chr22:41940651 POLR3H -0.62 -5.93 -0.47 2.82e-8 Vitiligo; TGCT cis rs1801251 1.000 rs283475 chr2:233654381 A/C cg08000102 chr2:233561755 GIGYF2 -0.62 -6.51 -0.5 1.66e-9 Coronary artery disease; TGCT cis rs13102973 0.720 rs7687641 chr4:135885739 C/T cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg23172400 chr8:95962367 TP53INP1 -0.29 -4.44 -0.37 1.97e-5 Type 2 diabetes; TGCT trans rs797680 0.856 rs12044657 chr1:93639596 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.83 -0.52 3.31e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs17376456 0.877 rs13169675 chr5:93331284 A/G cg21475434 chr5:93447410 FAM172A 0.64 4.73 0.39 6.09e-6 Diabetic retinopathy; TGCT cis rs12477438 0.798 rs17708218 chr2:99696284 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -5.99 -0.47 2.11e-8 Chronic sinus infection; TGCT cis rs9291683 0.552 rs10939655 chr4:10014642 A/T cg00071950 chr4:10020882 SLC2A9 0.76 10.38 0.68 1.55e-18 Bone mineral density; TGCT cis rs4819052 0.765 rs2838868 chr21:46714641 A/G cg06618935 chr21:46677482 NA 0.37 5.35 0.43 4e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs1005277 0.505 rs200937 chr10:38135772 T/C cg17830980 chr10:43048298 ZNF37B -0.72 -8.22 -0.59 2.27e-13 Extrinsic epigenetic age acceleration; TGCT cis rs3741404 0.560 rs17699798 chr11:63898806 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 -0.76 -7.29 -0.55 3.22e-11 Platelet count; TGCT cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7811142 1.000 rs4472444 chr7:100070758 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs12477438 0.765 rs2278895 chr2:99613484 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs2677744 0.534 rs6496739 chr15:91494430 C/T cg23684204 chr15:91497937 RCCD1 0.41 6.36 0.5 3.45e-9 Attention deficit hyperactivity disorder; TGCT cis rs854765 0.575 rs2955357 chr17:17946401 T/C cg04398451 chr17:18023971 MYO15A 0.33 5.44 0.44 2.77e-7 Total body bone mineral density; TGCT cis rs2204008 0.806 rs1589382 chr12:38408565 T/A cg26384229 chr12:38710491 ALG10B 0.84 7.51 0.56 1e-11 Bladder cancer; TGCT cis rs2742417 0.967 rs2742427 chr3:45736423 C/T cg04837898 chr3:45731254 SACM1L 0.51 5.07 0.41 1.43e-6 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.83e-5 Obesity-related traits; TGCT cis rs1997103 0.954 rs56030000 chr7:55405750 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs13191362 1.000 rs67025553 chr6:163011552 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs523522 0.962 rs4767912 chr12:120981202 A/G cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs5167 0.534 rs56803710 chr19:45481884 C/T cg09555818 chr19:45449301 APOC2 0.23 4.62 0.38 9.53e-6 Blood protein levels; TGCT cis rs7547997 0.685 rs7521814 chr1:158346996 G/A cg03528325 chr1:158223921 CD1A 0.33 4.56 0.38 1.22e-5 QRS duration; TGCT cis rs61990749 0.597 rs11624101 chr14:78138059 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.68 -4.76 -0.39 5.29e-6 Fibroblast growth factor basic levels; TGCT cis rs6967414 0.786 rs7782227 chr7:6748594 T/C cg09896999 chr7:6746977 ZNF12 -0.57 -6.37 -0.5 3.36e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs7666738 0.830 rs6827516 chr4:98971740 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg03264133 chr6:25882463 NA -0.57 -6.07 -0.48 1.45e-8 Blood metabolite levels; TGCT cis rs9311474 1.000 rs7629072 chr3:52305633 C/T cg10802521 chr3:52805072 NEK4 -0.58 -6.36 -0.5 3.52e-9 Electroencephalogram traits; TGCT cis rs1670533 0.932 rs2045067 chr4:1052355 C/T cg27284194 chr4:1044797 NA 0.68 5.76 0.46 6.38e-8 Recombination rate (females); TGCT cis rs4727443 0.653 rs6465759 chr7:99587980 T/C cg13334819 chr7:99746414 C7orf59 -0.58 -4.98 -0.41 2.07e-6 Interstitial lung disease; TGCT cis rs986417 0.901 rs7157458 chr14:60999852 C/T cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs5769765 0.671 rs138844 chr22:50184484 T/G cg15316289 chr22:50310904 ALG12;CRELD2 0.34 4.68 0.39 7.27e-6 Schizophrenia; TGCT cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg00101154 chr16:420108 MRPL28 -0.67 -7.59 -0.56 6.74e-12 Bone mineral density (spine);Bone mineral density; TGCT cis rs11779988 0.545 rs208759 chr8:17807929 G/C cg01800426 chr8:17659068 MTUS1 -0.64 -4.99 -0.41 2.02e-6 Breast cancer; TGCT trans rs6951245 0.554 rs75075857 chr7:1140298 C/T cg13565492 chr6:43139072 SRF -0.77 -7.35 -0.55 2.37e-11 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs427394 0.802 rs200841 chr5:6737134 A/G cg10857441 chr5:6722123 POLS -0.34 -8.21 -0.59 2.46e-13 Menopause (age at onset); TGCT cis rs1008375 1.000 rs11727312 chr4:17669185 C/T cg18681998 chr4:17616180 MED28 0.94 10.42 0.68 1.2e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13191362 1.000 rs7769686 chr6:163199467 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.76 0.52 4.71e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10883723 0.962 rs1056738 chr10:104236481 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 7.52 0.56 9.74e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg09323728 chr8:95962352 TP53INP1 -0.48 -6.22 -0.49 7.08e-9 Type 2 diabetes; TGCT cis rs7819412 0.777 rs1057626 chr8:10962800 T/C cg21775007 chr8:11205619 TDH -0.52 -5.06 -0.41 1.45e-6 Triglycerides; TGCT cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg16049864 chr8:95962084 TP53INP1 -0.72 -10.07 -0.67 8.64e-18 Type 2 diabetes; TGCT cis rs7267979 0.844 rs2257649 chr20:25263457 T/G cg03522245 chr20:25566470 NINL 0.55 5.55 0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4319547 0.695 rs12314643 chr12:122917423 C/T cg05707623 chr12:122985044 ZCCHC8 -0.64 -5.09 -0.42 1.27e-6 Body mass index; TGCT cis rs4711336 1.000 rs2296742 chr6:33659793 G/A cg14003231 chr6:33640908 ITPR3 0.28 4.51 0.38 1.49e-5 Height; TGCT cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg04352962 chr1:209979756 IRF6 0.61 4.67 0.39 7.72e-6 Cleft lip with or without cleft palate; TGCT cis rs12477438 0.765 rs2167930 chr2:99592551 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs66573146 0.831 rs68111914 chr4:6986677 C/T cg00086871 chr4:6988644 TBC1D14 0.94 4.62 0.38 9.61e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1005277 0.579 rs2504148 chr10:38400788 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6933660 0.512 rs13198669 chr6:151799924 A/G cg14416726 chr6:151773293 C6orf211;RMND1 0.74 4.66 0.39 7.97e-6 Menarche (age at onset); TGCT cis rs7216064 1.000 rs7210027 chr17:65977053 C/T cg12091567 chr17:66097778 LOC651250 0.83 6.38 0.5 3.16e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs8050907 0.744 rs8044698 chr16:4577069 A/G cg02183435 chr16:5121731 ALG1 0.74 4.46 0.37 1.8e-5 Obesity-related traits; TGCT cis rs3020736 0.500 rs4147638 chr22:42487900 G/A cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs896854 0.516 rs12679044 chr8:95891356 C/A cg09323728 chr8:95962352 TP53INP1 -0.38 -4.48 -0.37 1.65e-5 Type 2 diabetes; TGCT trans rs1864982 0.685 rs10062859 chr5:146211917 C/T cg07017998 chr4:733617 PCGF3 0.28 7.12 0.54 7.8e-11 Alcohol dependence; TGCT cis rs1568889 0.838 rs12273631 chr11:28042135 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.94 11.28 0.71 9.55e-21 Bipolar disorder; TGCT cis rs675209 0.559 rs17762454 chr6:7213200 C/T cg27097018 chr6:6320614 F13A1 0.37 5.39 0.44 3.35e-7 Urate levels; TGCT cis rs66561647 0.719 rs7821928 chr8:128939295 G/A cg11792826 chr8:129160931 MIR1208 0.22 4.95 0.41 2.37e-6 Hemoglobin concentration; TGCT cis rs748404 0.578 rs4547312 chr15:43632138 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.94 0.41 2.51e-6 Lung cancer; TGCT cis rs6542838 0.704 rs13011428 chr2:99528305 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.55 -5.14 -0.42 1.04e-6 Fear of minor pain; TGCT cis rs9650657 0.529 rs10108618 chr8:10953092 A/G cg21775007 chr8:11205619 TDH -0.55 -5.3 -0.43 5.23e-7 Neuroticism; TGCT cis rs11122272 0.735 rs2247124 chr1:231493687 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -6.82 -0.52 3.61e-10 Hemoglobin concentration; TGCT cis rs116095464 0.558 rs13357299 chr5:242211 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.68 4.49 0.37 1.59e-5 Breast cancer; TGCT cis rs6500602 0.701 rs4785971 chr16:4577090 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.27 4.9 0.4 2.94e-6 Schizophrenia; TGCT cis rs2380220 0.606 rs7747776 chr6:96005852 C/T cg04719120 chr6:96025338 MANEA 0.6 4.87 0.4 3.37e-6 Behavioural disinhibition (generation interaction); TGCT cis rs8180040 0.764 rs13061071 chr3:47138708 G/A cg27129171 chr3:47204927 SETD2 0.73 9.48 0.65 2.25e-16 Colorectal cancer; TGCT cis rs2952156 0.652 rs11869286 chr17:37813856 C/G cg00129232 chr17:37814104 STARD3 -0.23 -4.8 -0.4 4.43e-6 Asthma; TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg27535305 chr1:53392650 SCP2 -0.28 -5.74 -0.46 6.91e-8 Monocyte count; TGCT cis rs6669072 0.528 rs3856226 chr1:91245109 C/T cg08895590 chr1:91227319 NA 0.36 4.63 0.38 9.27e-6 Cognitive function; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg04234412 chr22:24373322 LOC391322 -0.91 -10.67 -0.69 2.98e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12497850 0.931 rs9840050 chr3:49133310 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.66 0.45 9.84e-8 Parkinson's disease; TGCT trans rs9388451 0.772 rs1268064 chr6:126042578 G/A cg05039488 chr6:79577232 IRAK1BP1 0.7 7.4 0.55 1.84e-11 Brugada syndrome; TGCT cis rs2847281 0.764 rs2847276 chr18:12777948 A/C cg23598886 chr18:12777645 NA 0.36 4.54 0.38 1.3e-5 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs7937682 0.737 rs682239 chr11:111425105 A/G cg09085632 chr11:111637200 PPP2R1B 0.81 8.38 0.6 9.75e-14 Primary sclerosing cholangitis; TGCT cis rs7582180 0.681 rs6754176 chr2:100995691 C/T cg14675211 chr2:100938903 LONRF2 0.47 4.45 0.37 1.89e-5 Intelligence (multi-trait analysis); TGCT cis rs7000551 0.751 rs2449340 chr8:22389900 T/G cg12081754 chr8:22256438 SLC39A14 0.28 4.66 0.39 8.01e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4888262 0.526 rs6564142 chr16:74590047 T/C cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 7.94e-11 Testicular germ cell tumor; TGCT cis rs12048904 0.595 rs2295280 chr1:101342497 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.71 7.39 0.55 1.92e-11 Multiple sclerosis; TGCT cis rs8072100 0.967 rs8072644 chr17:45653364 A/T cg08085267 chr17:45401833 C17orf57 0.43 4.77 0.39 5.01e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs13424612 0.965 rs4149544 chr2:240943162 C/T cg26363272 chr2:240904871 NDUFA10 0.28 4.67 0.39 7.7e-6 Odorant perception (isobutyraldehyde); TGCT cis rs17102423 0.589 rs4899162 chr14:65614126 G/T cg11161011 chr14:65562177 MAX -0.41 -5.66 -0.45 9.83e-8 Obesity-related traits; TGCT cis rs10791323 0.559 rs10750548 chr11:133729469 A/G cg03690763 chr11:133734501 NA -0.3 -4.53 -0.38 1.38e-5 Childhood ear infection; TGCT cis rs916888 0.821 rs199512 chr17:44857352 T/C cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9443645 0.901 rs9343843 chr6:79585625 C/T cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs826838 0.935 rs7301104 chr12:39182821 C/T cg13010199 chr12:38710504 ALG10B 0.77 6.09 0.48 1.31e-8 Heart rate; TGCT cis rs9443645 0.838 rs946022 chr6:79672133 G/T cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7647973 1.000 rs10155014 chr3:49432321 C/T cg05785598 chr3:49045655 WDR6 0.39 4.66 0.39 8e-6 Menarche (age at onset); TGCT cis rs7677751 0.806 rs7698425 chr4:55090656 C/T cg17187183 chr4:55093834 PDGFRA 0.53 6.92 0.53 2.19e-10 Corneal astigmatism; TGCT cis rs453301 0.653 rs7005133 chr8:8901222 T/G cg15556689 chr8:8085844 FLJ10661 0.86 7.99 0.58 7.9e-13 Joint mobility (Beighton score); TGCT cis rs1215050 0.765 rs1588018 chr4:98756324 G/C cg05340658 chr4:99064831 C4orf37 0.44 5.63 0.45 1.15e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12983728 0.732 rs34003091 chr19:58662254 T/C cg07378217 chr19:58662286 ZNF329 -0.9 -5.1 -0.42 1.25e-6 Cholesterol, total; TGCT cis rs116095464 0.558 rs10475136 chr5:232796 A/G cg22857025 chr5:266934 NA -0.33 -6.57 -0.51 1.22e-9 Breast cancer; TGCT cis rs7178572 0.568 rs11072653 chr15:77693934 C/T cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs6933660 0.665 rs6921042 chr6:151732385 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.87 -9.14 -0.63 1.48e-15 Menarche (age at onset); TGCT cis rs6500602 0.701 rs4786500 chr16:4525265 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.45 -6.49 -0.5 1.88e-9 Schizophrenia; TGCT cis rs7959452 0.868 rs10878967 chr12:69740869 T/C cg14784868 chr12:69753453 YEATS4 0.7 7.22 0.54 4.55e-11 Blood protein levels; TGCT cis rs901683 0.702 rs78757497 chr10:46161918 T/C cg18240400 chr10:46168597 ANUBL1 0.56 4.61 0.38 9.7e-6 Red blood cell traits;Mean corpuscular volume; TGCT cis rs972578 0.561 rs5759113 chr22:43443952 C/G cg03373887 chr22:44389424 SAMM50 0.21 4.53 0.38 1.36e-5 Mean platelet volume; TGCT cis rs10949662 0.961 rs77185864 chr7:157529621 G/T cg14168080 chr7:157504135 PTPRN2 -0.39 -4.6 -0.38 1.05e-5 Intelligence (multi-trait analysis); TGCT cis rs8031584 0.736 rs11635775 chr15:31160640 A/G cg08704250 chr15:31115839 NA -0.44 -6.49 -0.5 1.88e-9 Huntington's disease progression; TGCT cis rs838147 0.507 rs692854 chr19:49209464 C/A cg05248581 chr19:49925731 PTH2 0.42 4.55 0.38 1.26e-5 Dietary macronutrient intake; TGCT cis rs28595532 0.764 rs115011450 chr4:119778171 C/T cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs2836950 0.501 rs2056844 chr21:40670460 G/C cg17971929 chr21:40555470 PSMG1 -0.54 -4.93 -0.4 2.56e-6 Menarche (age at onset); TGCT cis rs7192750 0.586 rs1981874 chr16:71897244 C/T cg06353428 chr16:71660113 MARVELD3 -0.91 -7.93 -0.58 1.1e-12 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs8056742 0.643 rs55877407 chr16:85087310 T/A cg00229868 chr16:85520891 NA 0.36 4.83 0.4 4.03e-6 Amyotrophic lateral sclerosis; TGCT cis rs6484504 0.576 rs158139 chr11:31216076 C/T cg26647111 chr11:31128758 NA -0.34 -4.62 -0.38 9.36e-6 Red blood cell count; TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg10108389 chr3:44770937 ZNF501 -0.47 -4.64 -0.38 8.67e-6 Depressive symptoms; TGCT cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg08219700 chr8:58056026 NA 0.41 4.94 0.41 2.47e-6 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.924 rs2535629 chr3:52833219 C/T cg10802521 chr3:52805072 NEK4 -0.67 -7.4 -0.55 1.85e-11 Bipolar disorder; TGCT cis rs74233809 1.000 rs35125602 chr10:104656039 G/A cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs11105298 0.891 rs11105310 chr12:89918677 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs11958404 0.789 rs72818145 chr5:157476552 G/C cg05962755 chr5:157440814 NA 0.35 4.48 0.37 1.65e-5 IgG glycosylation; TGCT cis rs2072499 1.000 rs2253809 chr1:156172125 T/C cg25208724 chr1:156163844 SLC25A44 1.11 16.13 0.82 3.11e-32 Testicular germ cell tumor; TGCT cis rs2019216 0.542 rs1987424 chr17:21874036 G/A cg22648282 chr17:21454238 C17orf51 -0.56 -5.51 -0.44 1.95e-7 Pelvic organ prolapse; TGCT cis rs1395 1.000 rs1275530 chr2:27432547 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.49 -6.62 -0.51 9.77e-10 Blood metabolite levels; TGCT cis rs950169 0.881 rs72750843 chr15:85135783 C/T cg11189052 chr15:85197271 WDR73 0.77 6.5 0.5 1.76e-9 Schizophrenia; TGCT cis rs56104184 0.723 rs73063522 chr19:49408358 C/G cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg07507251 chr3:52567010 NT5DC2 -0.45 -6.3 -0.49 4.7e-9 Electroencephalogram traits; TGCT cis rs7119 0.636 rs11635606 chr15:77819591 A/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.55 -0.38 1.27e-5 Type 2 diabetes; TGCT cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.71 7.06 0.54 1.07e-10 Prudent dietary pattern; TGCT cis rs4595586 0.545 rs1156707 chr12:39372451 G/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7588654 0.793 rs17608726 chr2:219947002 G/A cg06736663 chr2:219754761 WNT10A -0.48 -4.79 -0.39 4.72e-6 Height; TGCT cis rs2033711 0.870 rs4801583 chr19:58918405 A/G cg04608855 chr19:58913158 NA 0.61 6.18 0.49 8.34e-9 Uric acid clearance; TGCT cis rs6952808 0.609 rs10232234 chr7:1948110 G/T cg04267008 chr7:1944627 MAD1L1 -0.36 -4.72 -0.39 6.34e-6 Bipolar disorder and schizophrenia; TGCT cis rs9611519 0.780 rs5751072 chr22:41656509 C/T cg06634786 chr22:41940651 POLR3H -0.55 -5.06 -0.41 1.46e-6 Neuroticism; TGCT cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.791 rs1830231 chr4:99026185 A/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12049351 0.774 rs34232465 chr1:229631112 C/T cg12130225 chr1:229698885 NA 0.39 4.58 0.38 1.12e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs524281 0.647 rs2302883 chr11:65824994 T/C cg00563793 chr11:65837595 PACS1 0.55 4.84 0.4 3.79e-6 Electroencephalogram traits; TGCT cis rs7917772 0.503 rs2031602 chr10:104307955 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 8.6 0.61 2.97e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9457247 1.000 rs2013815 chr6:167373812 T/A cg25258033 chr6:167368657 RNASET2 -0.18 -4.48 -0.37 1.65e-5 Crohn's disease; TGCT cis rs17376456 0.877 rs10044139 chr5:93407803 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs612683 0.735 rs3754131 chr1:100931073 A/C cg06223162 chr1:101003688 GPR88 0.31 4.89 0.4 3.09e-6 Breast cancer; TGCT cis rs7586879 0.616 rs12713422 chr2:25134497 A/C cg15423357 chr2:25149977 NA 0.52 5.04 0.41 1.63e-6 Body mass index; TGCT cis rs12926788 0.689 rs34365165 chr16:24856208 G/A cg06028605 chr16:24865363 SLC5A11 0.43 4.87 0.4 3.34e-6 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6570726 0.875 rs373313 chr6:145857791 T/C cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs826838 0.967 rs826858 chr12:39116731 A/G cg26384229 chr12:38710491 ALG10B -0.86 -7.76 -0.57 2.68e-12 Heart rate; TGCT cis rs1799949 0.930 rs2298861 chr17:41176831 G/A cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs7715806 0.509 rs34349 chr5:74944868 A/G cg19683494 chr5:74908142 NA -0.64 -5.87 -0.47 3.74e-8 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs12136530 0.593 rs881248 chr1:19733961 C/T cg24875000 chr1:19041556 PAX7 0.27 4.82 0.4 4.15e-6 Lead levels in blood; TGCT cis rs9467711 0.606 rs9393711 chr6:26370659 C/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs968451 1.000 rs11704615 chr22:39696834 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.87 7.73 0.57 3.17e-12 Primary biliary cholangitis; TGCT cis rs12701220 0.894 rs12539012 chr7:1052133 G/A cg27454412 chr7:1067447 C7orf50 -0.48 -4.44 -0.37 1.98e-5 Bronchopulmonary dysplasia; TGCT cis rs617219 0.710 rs6874525 chr5:78574237 C/T cg23514016 chr5:78407564 BHMT -0.32 -4.87 -0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2562456 0.920 rs2650784 chr19:21666597 T/C cg25650185 chr19:21324782 ZNF431 0.56 4.83 0.4 4.02e-6 Pain; TGCT cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg16423285 chr20:60520624 NA -0.7 -7.45 -0.56 1.42e-11 Body mass index; TGCT cis rs67072384 1.000 rs12292781 chr11:72448385 A/C cg03713592 chr11:72463424 ARAP1 -0.94 -4.8 -0.4 4.41e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs3806843 1.000 rs10072015 chr5:140170655 A/T cg19875535 chr5:140030758 IK -0.37 -6.26 -0.49 5.83e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4700695 0.719 rs1643415 chr5:65447087 T/C cg21114390 chr5:65439923 SFRS12 -0.84 -7.45 -0.56 1.35e-11 Facial morphology (factor 19); TGCT cis rs797680 0.856 rs4847410 chr1:93802781 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.07 -0.41 1.4e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs7726839 0.540 rs3749618 chr5:602650 A/G cg11887960 chr12:57824829 NA 1.17 9.69 0.66 7.25e-17 Obesity-related traits; TGCT cis rs2303745 0.589 rs891018 chr19:17396761 C/T cg04248312 chr19:17393744 ANKLE1 0.35 6.14 0.48 1.01e-8 Systemic lupus erythematosus; TGCT cis rs6570726 0.755 rs2103633 chr6:145894021 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT trans rs2749592 0.550 rs7917262 chr10:37874602 A/C cg17830980 chr10:43048298 ZNF37B 0.65 6.85 0.52 2.99e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs909685 0.538 rs5757589 chr22:39668353 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.73 8.29 0.6 1.61e-13 Rheumatoid arthritis; TGCT cis rs17711722 0.727 rs1880555 chr7:65432567 T/C cg18876405 chr7:65276391 NA 0.38 5.89 0.47 3.4e-8 Calcium levels; TGCT cis rs11096990 0.613 rs35391082 chr4:39192653 C/T cg20847110 chr4:39482781 LOC401127 0.16 4.52 0.38 1.42e-5 Cognitive function; TGCT cis rs56399783 0.901 rs17132594 chr7:2775102 G/A cg19731401 chr7:2775893 GNA12 0.35 4.98 0.41 2.04e-6 Childhood ear infection; TGCT cis rs1153858 1.000 rs12439274 chr15:45636667 A/G cg14582100 chr15:45693742 SPATA5L1 0.5 5.77 0.46 6.02e-8 Homoarginine levels; TGCT cis rs317689 0.718 rs645026 chr12:69757931 G/A cg20891283 chr12:69753455 YEATS4 0.56 4.71 0.39 6.52e-6 Response to diuretic therapy; TGCT cis rs6570726 0.846 rs6570698 chr6:145918635 C/G cg23711669 chr6:146136114 FBXO30 0.83 8.64 0.61 2.4e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.882 rs17050672 chr3:10025463 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.42 -0.5 2.58e-9 Alzheimer's disease; TGCT cis rs2657888 1.000 rs7310284 chr12:56935652 A/G cg23002907 chr12:56915593 RBMS2 0.48 6.59 0.51 1.14e-9 Adiponectin levels; TGCT cis rs116095464 0.558 rs55776650 chr5:273826 G/A cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg01171360 chr6:293285 DUSP22 -0.77 -7.85 -0.58 1.67e-12 Menopause (age at onset); TGCT cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg03303774 chr4:1407052 NA 0.28 4.58 0.38 1.12e-5 Obesity-related traits; TGCT cis rs514406 0.861 rs7524476 chr1:53240212 C/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs4722585 0.605 rs3753098 chr7:26198040 C/T cg03781084 chr7:26191726 NFE2L3 0.47 4.72 0.39 6.24e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs13108904 0.936 rs4974540 chr4:1213463 C/T cg05665937 chr4:1216051 CTBP1 0.26 5.12 0.42 1.13e-6 Obesity-related traits; TGCT cis rs35160687 0.901 rs10200186 chr2:86527423 C/T cg12542933 chr2:85804724 VAMP8 0.41 4.9 0.4 2.97e-6 Night sleep phenotypes; TGCT cis rs9303401 0.614 rs35057477 chr17:57097064 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.82 0.46 4.8e-8 Cognitive test performance; TGCT cis rs6967414 0.786 rs3757482 chr7:6748927 A/G cg00387323 chr7:6746715 ZNF12 0.79 4.92 0.4 2.67e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs669446 0.561 rs1143701 chr1:44084739 C/T cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs17601876 0.651 rs12908960 chr15:51545860 G/A cg19946085 chr15:51559439 CYP19A1 -0.34 -4.86 -0.4 3.5e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs926938 0.563 rs360642 chr1:115425429 C/G cg12756093 chr1:115239321 AMPD1 0.4 6.34 0.49 3.97e-9 Autism; TGCT cis rs75686122 1.000 rs2114249 chr8:104719519 T/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9611565 0.649 rs4822050 chr22:42177453 C/G cg03806693 chr22:41940476 POLR3H -0.88 -8.55 -0.61 3.93e-14 Vitiligo; TGCT cis rs4722166 0.645 rs1404006 chr7:22795077 T/C cg26061582 chr7:22766209 IL6 0.49 6.28 0.49 5.1e-9 Lung cancer; TGCT cis rs9788721 0.836 rs2568494 chr15:78740964 G/A cg18825076 chr15:78729989 IREB2 -0.33 -5.32 -0.43 4.68e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs7095607 0.521 rs2673792 chr10:69927959 T/A cg18986048 chr10:69913749 MYPN 0.6 6.29 0.49 4.96e-9 Lung function (FVC); TGCT trans rs561341 0.505 rs41291021 chr17:30410689 C/A cg20587970 chr11:113659929 NA -1.01 -8.24 -0.59 2.09e-13 Hip circumference adjusted for BMI; TGCT cis rs6582630 0.599 rs8189525 chr12:38424982 A/C cg26384229 chr12:38710491 ALG10B 0.56 5.13 0.42 1.1e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs60871478 0.853 rs62432864 chr7:808405 T/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.45 4.51 0.38 1.46e-5 Cerebrospinal P-tau181p levels; TGCT cis rs6570726 0.905 rs1355146 chr6:145781741 A/C cg23711669 chr6:146136114 FBXO30 -0.7 -6.5 -0.5 1.78e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs57590327 0.503 rs2372906 chr3:81504673 G/A cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT trans rs901683 0.702 rs73292848 chr10:46169752 T/C cg18828137 chr12:52968145 KRT74 -0.61 -6.84 -0.52 3.2e-10 Red blood cell traits;Mean corpuscular volume; TGCT cis rs1150668 0.799 rs2142730 chr6:28266149 T/C cg13525197 chr6:28411240 ZSCAN23 -0.49 -4.86 -0.4 3.52e-6 Pubertal anthropometrics; TGCT cis rs1903068 0.853 rs28680424 chr4:56009245 T/C cg01777861 chr4:56023843 NA 0.54 6.11 0.48 1.21e-8 Endometriosis; TGCT cis rs2295359 0.892 rs17375018 chr1:67655147 A/G cg12940439 chr1:67600707 NA -0.61 -6.1 -0.48 1.22e-8 Psoriasis; TGCT cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg12756686 chr19:29218302 NA 0.78 6.69 0.51 6.93e-10 Methadone dose in opioid dependence; TGCT cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs8051431 0.840 rs7185272 chr16:72013797 G/C cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs7605378 0.528 rs281787 chr2:200784238 C/T cg17644776 chr2:200775616 C2orf69 -0.32 -7.16 -0.54 6.12e-11 Osteoporosis; TGCT cis rs9902453 0.900 rs12451122 chr17:28486376 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs13108904 0.935 rs1620928 chr4:1279124 C/T cg00684032 chr4:1343700 KIAA1530 -0.22 -4.73 -0.39 6.06e-6 Obesity-related traits; TGCT cis rs1218582 0.741 rs883718 chr1:154846274 C/T cg24250549 chr1:154909240 PMVK 0.58 5.76 0.46 6.21e-8 Prostate cancer; TGCT cis rs7208859 0.673 rs11658435 chr17:29228561 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11792861 0.926 rs11787878 chr9:111866749 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.48 0.37 1.66e-5 Menarche (age at onset); TGCT cis rs78461346 0.908 rs77207724 chr17:80506440 T/C cg15014069 chr17:80540666 FOXK2 0.4 5.04 0.41 1.62e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs1799949 0.930 rs66499067 chr17:41248484 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.92 0.4 2.64e-6 Menopause (age at onset); TGCT cis rs7552404 0.731 rs11161836 chr1:76354333 C/T cg03433033 chr1:76189801 ACADM 0.75 7.34 0.55 2.41e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs853679 0.567 rs7754960 chr6:28346945 G/C cg18815343 chr6:28367644 ZSCAN12 -0.52 -4.72 -0.39 6.26e-6 Depression; TGCT cis rs4727027 0.704 rs12704083 chr7:148909759 G/A cg23583168 chr7:148888333 NA -0.86 -10.99 -0.7 4.87e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4919694 1.000 rs4917986 chr10:104630181 T/C cg04362960 chr10:104952993 NT5C2 1.05 7.23 0.54 4.37e-11 Arsenic metabolism; TGCT cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg13409248 chr3:40428643 ENTPD3 0.54 4.52 0.38 1.41e-5 Renal cell carcinoma; TGCT cis rs4788570 0.615 rs6499526 chr16:71648299 C/T cg06353428 chr16:71660113 MARVELD3 1.54 12.75 0.75 2.57e-24 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.696 rs67487205 chr1:76373756 T/C cg03433033 chr1:76189801 ACADM 0.76 7.2 0.54 5.19e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.830 rs11944107 chr4:98931638 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs11167764 1.000 rs10057309 chr5:141479870 T/C cg23435118 chr5:141488016 NDFIP1 -0.29 -4.83 -0.4 3.94e-6 Crohn's disease; TGCT cis rs7666738 0.830 rs35531558 chr4:98938217 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10465746 0.725 rs6694752 chr1:84389960 C/T cg10977910 chr1:84465055 TTLL7 0.73 7.31 0.55 2.95e-11 Obesity-related traits; TGCT cis rs10876993 0.928 rs1689595 chr12:58056763 C/T cg15848620 chr12:58087721 OS9 -0.73 -6.07 -0.48 1.44e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs1891275 0.515 rs11186666 chr10:93477919 T/C cg07889827 chr10:93443413 NA -0.32 -6.75 -0.52 5.12e-10 Intelligence (multi-trait analysis); TGCT cis rs950169 0.810 rs2879976 chr15:85109578 G/A cg11189052 chr15:85197271 WDR73 0.77 6.42 0.5 2.68e-9 Schizophrenia; TGCT cis rs11031096 0.811 rs4910599 chr11:4156040 T/A cg18678763 chr11:4115507 RRM1 -0.46 -5.79 -0.46 5.36e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs478304 0.651 rs4930319 chr11:65555458 G/C cg27068330 chr11:65405492 SIPA1 -0.95 -9.23 -0.64 8.93e-16 Acne (severe); TGCT cis rs727563 0.594 rs5758408 chr22:42077737 A/C cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3749237 0.595 rs11130192 chr3:49467206 C/G cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs6815814 0.861 rs6843043 chr4:38843136 A/G cg02016764 chr4:38805732 TLR1 -0.29 -4.68 -0.39 7.51e-6 Breast cancer; TGCT cis rs7119 0.931 rs7176875 chr15:77832675 A/G cg27398640 chr15:77910606 LINGO1 0.26 4.89 0.4 3.12e-6 Type 2 diabetes; TGCT cis rs78456975 1.000 rs13400784 chr2:1564473 T/A cg01028140 chr2:1542097 TPO -0.32 -4.5 -0.37 1.54e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9858542 0.953 rs1987628 chr3:49399259 G/A cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7582180 0.663 rs6542930 chr2:100944383 T/A cg14675211 chr2:100938903 LONRF2 0.49 4.89 0.4 3.02e-6 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs6875291 chr5:264192 T/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs151997 0.962 rs32482 chr5:50207118 T/C cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs1385374 0.800 rs12321679 chr12:129284791 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs7267979 0.753 rs404148 chr20:25447931 A/G cg16686733 chr20:25566563 NINL 0.49 4.59 0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.861 rs554760 chr1:53266749 G/A cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs60843830 1.000 rs62114544 chr2:269679 C/T cg00108164 chr2:264199 ACP1;SH3YL1 0.71 6.79 0.52 4.24e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10206020 0.921 rs10177509 chr2:1568536 T/C cg01028140 chr2:1542097 TPO -0.33 -5.22 -0.42 7.28e-7 IgG glycosylation; TGCT cis rs797680 0.856 rs7535628 chr1:93648728 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.03 -0.41 1.67e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6490294 0.898 rs57646770 chr12:112431212 T/C cg10833066 chr12:111807467 FAM109A 0.36 5.11 0.42 1.17e-6 Mean platelet volume; TGCT cis rs3812831 0.695 rs6560936 chr13:114945972 C/T cg06611532 chr13:114900021 NA -0.37 -6.78 -0.52 4.34e-10 Schizophrenia; TGCT cis rs7542091 0.704 rs2142907 chr1:210039505 T/C cg00989853 chr1:209979345 IRF6 0.42 4.44 0.37 1.97e-5 Monobrow; TGCT cis rs10193935 0.901 rs2088281 chr2:42672731 A/G cg27598129 chr2:42591480 NA 0.4 5.56 0.45 1.61e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.632 rs61461940 chr9:5157277 T/C cg02405213 chr9:5042618 JAK2 -0.76 -10.0 -0.67 1.28e-17 Pediatric autoimmune diseases; TGCT cis rs9911578 0.967 rs9894274 chr17:56977919 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs13185784 0.625 rs4270655 chr5:179645244 A/G cg04734276 chr5:178882605 NA 0.29 4.46 0.37 1.81e-5 TRAIL levels; TGCT cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg11301795 chr4:187892539 NA 0.31 4.69 0.39 6.98e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 0.920 rs116149978 chr4:119761069 A/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg06634786 chr22:41940651 POLR3H 0.84 7.89 0.58 1.32e-12 Vitiligo; TGCT cis rs916888 0.821 rs70600 chr17:44860021 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.57 -4.86 -0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs2801405 0.623 rs1444803 chr10:100624132 G/A cg04906546 chr1:208317836 PLXNA2 -0.3 -6.97 -0.53 1.67e-10 Obesity-related traits; TGCT cis rs727563 0.565 rs132774 chr22:42031953 C/G cg13695892 chr22:41940480 POLR3H -0.78 -7.4 -0.55 1.76e-11 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3733585 0.746 rs4318650 chr4:10016868 T/C cg00071950 chr4:10020882 SLC2A9 0.66 7.75 0.57 2.83e-12 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs17685 0.753 rs3757593 chr7:75678735 G/A cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1580019 0.665 rs34147895 chr7:32531796 G/C cg07520158 chr7:32535189 LSM5;AVL9 0.56 4.6 0.38 1.02e-5 Cognitive ability; TGCT trans rs10506458 0.915 rs17738485 chr12:63394932 T/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs6032067 0.516 rs6017530 chr20:43899731 G/A cg16667508 chr20:43936853 MATN4;RBPJL -0.38 -5.96 -0.47 2.38e-8 Blood protein levels; TGCT cis rs12200560 0.505 rs12192623 chr6:97081432 A/G cg06623918 chr6:96969491 KIAA0776 -0.58 -4.89 -0.4 3.09e-6 Coronary heart disease; TGCT cis rs7707921 0.767 rs6894520 chr5:81594748 C/T cg15871215 chr5:81402204 ATG10 -0.29 -4.61 -0.38 9.95e-6 Breast cancer; TGCT cis rs921968 0.541 rs3755041 chr2:219442499 A/T cg02176678 chr2:219576539 TTLL4 -0.49 -6.93 -0.53 1.99e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs769267 0.965 rs8103496 chr19:19386015 A/G cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs7666738 0.830 rs969049 chr4:98988857 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs637571 0.558 rs10896064 chr11:65641033 G/C cg04055107 chr11:65626734 MUS81;CFL1 -0.64 -6.7 -0.52 6.64e-10 Eosinophil percentage of white cells; TGCT cis rs1008375 1.000 rs2058339 chr4:17678456 C/T cg10189774 chr4:17578691 LAP3 0.54 5.06 0.41 1.44e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs59721556 0.655 rs2364582 chr14:78121114 A/G cg04906283 chr14:77965859 ISM2 0.4 4.5 0.37 1.53e-5 Response to paliperidone in schizophrenia (positive Marder score);Response to paliperidone in schizophrenia (PANSS score);Response to paliperidone in schizophrenia (CGI-S score);Red cell distribution width;Response to paliperidone in schizophrenia (Multivariate); TGCT cis rs2455799 0.613 rs6795100 chr3:15793798 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg24675658 chr1:53192096 ZYG11B 0.85 10.97 0.7 5.36e-20 Monocyte count; TGCT cis rs6939532 0.517 rs733528 chr6:26374903 A/G cg05738196 chr6:26577821 NA -0.51 -4.89 -0.4 3.08e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs616402 0.527 rs604814 chr1:10567122 G/A cg17425144 chr1:10567563 PEX14 0.56 8.14 0.59 3.58e-13 Breast size; TGCT cis rs6121246 0.559 rs6060952 chr20:30382108 T/G cg13852791 chr20:30311386 BCL2L1 0.83 8.16 0.59 3.22e-13 Mean corpuscular hemoglobin; TGCT cis rs9302001 0.662 rs34408365 chr13:95469123 T/C cg07483244 chr13:95358924 NA 0.37 4.84 0.4 3.86e-6 Panic disorder; TGCT cis rs7267979 1.000 rs1077889 chr20:25267893 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6540559 0.673 rs6540560 chr1:209982073 A/G cg04352962 chr1:209979756 IRF6 -0.61 -4.87 -0.4 3.37e-6 Cleft lip with or without cleft palate; TGCT cis rs763121 0.853 rs5757232 chr22:39071677 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs3902035 0.964 rs62423970 chr6:119010901 T/C cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs514406 0.505 rs146750 chr1:53183447 C/G cg22166914 chr1:53195759 ZYG11B 0.45 8.18 0.59 2.87e-13 Monocyte count; TGCT cis rs3935685 0.934 rs11630598 chr15:78006095 C/T cg03457338 chr15:78040120 NA -0.22 -5.24 -0.43 6.62e-7 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs2866863 chr11:49953242 C/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs12579753 0.879 rs35087297 chr12:82133398 C/T cg07988820 chr12:82153109 PPFIA2 -0.68 -7.32 -0.55 2.7e-11 Resting heart rate; TGCT cis rs9906944 0.707 rs9916472 chr17:47109998 C/T cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs4972806 0.814 rs2113560 chr2:177030986 T/C cg14324370 chr2:177042789 NA 0.73 6.74 0.52 5.28e-10 IgG glycosylation; TGCT cis rs6684514 1.000 rs11264464 chr1:156250887 T/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg11301795 chr4:187892539 NA 0.32 4.92 0.4 2.73e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6543140 0.964 rs10196334 chr2:103090041 T/C cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs12753569 0.934 rs6676370 chr1:76490185 G/T cg00791851 chr1:76518896 NA -0.39 -5.17 -0.42 8.94e-7 Personality dimensions; TGCT cis rs7267979 0.509 rs6115218 chr20:25566485 A/G cg17729667 chr20:25566382 NINL 0.4 4.49 0.37 1.63e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9858542 0.537 rs67882627 chr3:49380441 A/T cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.59 0.38 1.08e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs9393692 0.902 rs6456711 chr6:26302572 A/C cg00631329 chr6:26305371 NA -0.46 -6.92 -0.53 2.19e-10 Educational attainment; TGCT cis rs9436747 0.641 rs11208678 chr1:66049691 A/C cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.73 0.39 5.97e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7681440 0.904 rs28750169 chr4:90774303 A/G cg20003494 chr4:90757398 SNCA -0.59 -5.52 -0.44 1.9e-7 Dementia with Lewy bodies; TGCT cis rs57590327 0.527 rs9845467 chr3:81614473 G/A cg07356753 chr3:81810745 GBE1 -0.61 -5.1 -0.42 1.24e-6 Extraversion; TGCT cis rs28595532 0.920 rs114094671 chr4:119753540 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2806561 0.765 rs2806556 chr1:23502850 G/A cg12483005 chr1:23474871 LUZP1 0.37 4.77 0.39 5.03e-6 Height; TGCT cis rs9291683 0.552 rs17187075 chr4:9990328 G/C cg00071950 chr4:10020882 SLC2A9 0.71 9.35 0.64 4.62e-16 Bone mineral density; TGCT cis rs7769051 1.000 rs12203977 chr6:133122760 A/G cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT trans rs2727020 0.757 rs7924526 chr11:49267043 G/A cg15704280 chr7:45808275 SEPT13 0.73 8.14 0.59 3.47e-13 Coronary artery disease; TGCT cis rs597539 0.616 rs631001 chr11:68642974 C/T cg06028808 chr11:68637592 NA 0.52 6.73 0.52 5.58e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10838634 1.000 rs7115986 chr11:46829174 T/A cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs9911578 0.933 rs2531725 chr17:56517962 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.26 0.64 7.61e-16 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs35822567 chr4:98654138 G/A cg05340658 chr4:99064831 C4orf37 0.46 5.42 0.44 3.01e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9368481 0.761 rs4713062 chr6:26948195 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.46 -5.22 -0.42 7.38e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs614226 0.938 rs7972244 chr12:120994872 A/G cg10072921 chr12:121022843 NA -0.44 -4.74 -0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs16854884 0.739 rs1075113 chr3:143760535 C/T cg06585982 chr3:143692056 C3orf58 0.54 4.54 0.38 1.33e-5 Economic and political preferences (feminism/equality); TGCT cis rs4733781 0.563 rs7387699 chr8:131339029 T/C cg16277922 chr8:131349729 ASAP1 -0.59 -10.18 -0.67 4.59e-18 Tuberculosis; TGCT cis rs12931792 0.712 rs4787495 chr16:30165725 C/T cg17640201 chr16:30407289 ZNF48 -0.61 -5.54 -0.45 1.72e-7 Tonsillectomy; TGCT cis rs739496 0.546 rs11066055 chr12:112313216 A/T cg10833066 chr12:111807467 FAM109A 0.38 5.42 0.44 2.97e-7 Platelet count; TGCT cis rs929354 0.772 rs3802124 chr7:156970609 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs6684514 1.000 rs66965793 chr1:156285814 G/A cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9926296 0.568 rs4420527 chr16:89814188 C/T cg26513180 chr16:89883248 FANCA -1.04 -13.91 -0.78 4.47e-27 Vitiligo; TGCT cis rs4699052 0.963 rs56144793 chr4:104150653 A/G cg16532752 chr4:104119610 CENPE -0.58 -5.46 -0.44 2.43e-7 Testicular germ cell tumor; TGCT cis rs10782582 0.593 rs11801414 chr1:76124517 G/A cg22875332 chr1:76189707 ACADM -0.54 -6.36 -0.5 3.61e-9 Daytime sleep phenotypes; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg11905131 chr22:24372483 LOC391322 -0.87 -10.04 -0.67 1.03e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs868036 0.681 rs4776375 chr15:68085555 G/A cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs7647973 0.626 rs62262672 chr3:49655927 T/A cg03060546 chr3:49711283 APEH -0.61 -5.14 -0.42 1.03e-6 Menarche (age at onset); TGCT cis rs6430585 0.584 rs4954276 chr2:136402117 A/G cg07169764 chr2:136633963 MCM6 0.66 5.8 0.46 5.18e-8 Corneal structure; TGCT cis rs9916302 0.706 rs8075737 chr17:37727316 C/T cg07936489 chr17:37558343 FBXL20 0.88 7.1 0.54 8.42e-11 Glomerular filtration rate (creatinine); TGCT cis rs13191362 0.507 rs2849524 chr6:163127070 C/T cg06582575 chr6:163149167 PACRG;PARK2 -0.59 -5.75 -0.46 6.6e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs854765 0.693 rs12941039 chr17:17765655 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.75 -7.92 -0.58 1.12e-12 Total body bone mineral density; TGCT cis rs6684514 0.922 rs12128785 chr1:156269389 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4925386 1.000 rs6121990 chr20:60919263 G/A cg06026331 chr20:60912101 LAMA5 -0.3 -5.5 -0.44 2.12e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs17345786 0.798 rs4257518 chr3:101281709 C/T cg11279151 chr3:101281821 RG9MTD1 0.45 10.63 0.69 3.76e-19 Colonoscopy-negative controls vs population controls; TGCT cis rs9914544 1.000 rs1634411 chr17:18833810 C/T cg26378065 chr17:18585709 ZNF286B 0.54 4.85 0.4 3.67e-6 Educational attainment (years of education); TGCT cis rs1023500 1.000 rs1023500 chr22:42340844 C/T cg04692870 chr22:42525206 CYP2D6 0.33 5.0 0.41 1.9e-6 Schizophrenia; TGCT cis rs4566357 0.615 rs2396445 chr2:227917726 C/G cg11843606 chr2:227700838 RHBDD1 -0.54 -5.09 -0.42 1.28e-6 Coronary artery disease; TGCT cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs9467711 0.606 rs9379859 chr6:26369549 C/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs13418410 0.539 rs1545399 chr2:33843801 A/G cg04131969 chr2:33951647 MYADML -0.78 -7.55 -0.56 8.23e-12 Non-response to antidepressants and depression; TGCT cis rs425277 0.585 rs3128294 chr1:2065343 G/C cg24578937 chr1:2090814 PRKCZ -0.26 -6.38 -0.5 3.2e-9 Height; TGCT trans rs6089829 0.962 rs2314130 chr20:61665129 G/T cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7726839 0.574 rs11739866 chr5:636299 C/T cg09021430 chr5:549028 NA -0.38 -5.11 -0.42 1.21e-6 Obesity-related traits; TGCT cis rs11148252 0.904 rs3892337 chr13:53029485 C/G cg00495681 chr13:53174319 NA 0.58 6.06 0.48 1.48e-8 Lewy body disease; TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.7 4.98 0.41 2.08e-6 Platelet count; TGCT cis rs11031096 0.655 rs1822289 chr11:4212184 T/C cg08557956 chr11:4115526 RRM1 -0.49 -4.56 -0.38 1.2e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7975161 0.638 rs4592489 chr12:104619699 C/T cg25273343 chr12:104657179 TXNRD1 -0.28 -4.45 -0.37 1.9e-5 Toenail selenium levels; TGCT cis rs12780845 0.540 rs10904903 chr10:17238336 T/A cg01003015 chr10:17271136 VIM -0.5 -4.55 -0.38 1.26e-5 Homocysteine levels; TGCT cis rs9354352 1.000 rs9354352 chr6:66696272 T/C cg07460842 chr6:66804631 NA 0.65 6.68 0.51 7.29e-10 Initial pursuit acceleration in psychotic disorders; TGCT cis rs909674 0.690 rs5750825 chr22:39831278 A/G cg24399712 chr22:39784796 NA -1.06 -10.99 -0.7 4.84e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs12643440 0.538 rs56290948 chr4:17138950 C/T cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs10992471 0.603 rs10761155 chr9:95153729 C/G cg13798575 chr9:95087839 CENPP;NOL8 -0.64 -5.91 -0.47 3.03e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9611565 0.559 rs7290991 chr22:41964361 C/G cg13695892 chr22:41940480 POLR3H -0.87 -8.17 -0.59 2.95e-13 Vitiligo; TGCT cis rs4919694 1.000 rs58317752 chr10:104799267 T/A cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs17345786 0.628 rs11718446 chr3:101552553 C/T cg12386194 chr3:101231763 SENP7 0.51 5.06 0.41 1.48e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2228479 1.000 rs11642267 chr16:89957635 T/C cg06558623 chr16:89946397 TCF25 0.57 6.52 0.51 1.62e-9 Skin colour saturation; TGCT cis rs875971 0.800 rs427557 chr7:65519250 A/G cg18876405 chr7:65276391 NA 0.33 4.95 0.41 2.39e-6 Aortic root size; TGCT cis rs7772486 0.790 rs9791313 chr6:146266172 T/C cg23711669 chr6:146136114 FBXO30 -0.85 -9.7 -0.66 6.73e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2762353 0.603 rs12201071 chr6:25778055 C/T cg03264133 chr6:25882463 NA 0.47 4.75 0.39 5.54e-6 Blood metabolite levels; TGCT cis rs11030122 0.661 rs963998 chr11:4062803 A/G cg18678763 chr11:4115507 RRM1 -0.46 -5.57 -0.45 1.53e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs7085104 0.632 rs7097872 chr10:104606636 C/T cg15744005 chr10:104629667 AS3MT -0.43 -5.37 -0.43 3.77e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs1577917 0.958 rs36035797 chr6:86562880 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs9650657 0.644 rs7012206 chr8:10697015 A/G cg16664915 chr8:10907788 XKR6 -0.28 -4.54 -0.38 1.31e-5 Neuroticism; TGCT trans rs1005277 0.563 rs2800550 chr10:38482929 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.51 0.61 4.68e-14 Extrinsic epigenetic age acceleration; TGCT cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg05665937 chr4:1216051 CTBP1 0.24 4.65 0.39 8.32e-6 Obesity-related traits; TGCT cis rs6076065 0.925 rs6083106 chr20:23368809 A/C cg11657817 chr20:23433608 CST11 0.28 4.55 0.38 1.25e-5 Facial morphology (factor 15, philtrum width); TGCT cis rs601338 1 rs601338 chr19:49206674 G/A cg13540341 chr19:49222985 MAMSTR -0.34 -4.66 -0.39 8.06e-6 Number of common colds;Blood metabolite levels;Blood metabolite ratios; TGCT cis rs7552404 0.924 rs7546641 chr1:76158035 T/C cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2580764 0.515 rs4672005 chr2:55246551 C/T cg09592903 chr2:55203963 RTN4 -0.26 -5.76 -0.46 6.14e-8 Mean platelet volume; TGCT cis rs7208859 0.623 rs11652631 chr17:29060766 A/G cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg11279151 chr3:101281821 RG9MTD1 -0.45 -9.64 -0.65 9.35e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs7208859 0.524 rs28760584 chr17:29141017 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6840360 1.000 rs7671651 chr4:152597202 C/G cg17479576 chr4:152424074 FAM160A1 -0.49 -5.18 -0.42 8.55e-7 Intelligence (multi-trait analysis); TGCT cis rs9326248 1.000 rs664971 chr11:117070857 A/G cg26566898 chr11:117069891 TAGLN -0.35 -4.44 -0.37 2e-5 Blood protein levels; TGCT cis rs853679 0.546 rs200952 chr6:27836976 C/T cg01031101 chr6:28227091 NKAPL -0.49 -4.66 -0.39 8.09e-6 Depression; TGCT cis rs68170813 0.559 rs76020313 chr7:106877468 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs826838 0.806 rs826873 chr12:39121305 G/A cg13010199 chr12:38710504 ALG10B -0.64 -5.07 -0.41 1.39e-6 Heart rate; TGCT cis rs28595532 0.764 rs56309519 chr4:119754158 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs13256369 1.000 rs13266699 chr8:8570313 A/T cg18904891 chr8:8559673 CLDN23 -0.59 -5.54 -0.45 1.73e-7 Obesity-related traits; TGCT cis rs10791097 0.720 rs6590516 chr11:130733393 G/T cg14779329 chr11:130786720 SNX19 0.29 4.97 0.41 2.18e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs6089829 0.925 rs3746748 chr20:61667526 C/T cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467711 0.790 rs55706012 chr6:26266311 A/C cg16898833 chr6:26189333 HIST1H4D 1.33 5.93 0.47 2.74e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs9549260 0.591 rs9577115 chr13:41276553 T/C cg21288729 chr13:41239152 FOXO1 0.94 9.32 0.64 5.56e-16 Red blood cell count; TGCT cis rs4689388 0.926 rs4689391 chr4:6280449 G/A cg00701064 chr4:6280414 WFS1 0.45 6.19 0.49 8e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs7255045 0.742 rs6511841 chr19:12955149 G/T cg23899408 chr19:12877188 HOOK2 -0.58 -4.78 -0.39 4.85e-6 Mean corpuscular volume; TGCT cis rs78461346 1.000 rs78014296 chr17:80532744 A/G cg15014069 chr17:80540666 FOXK2 0.4 4.99 0.41 1.97e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs73198271 0.729 rs67000451 chr8:8605083 A/G ch.8.214553F chr8:8189620 PRAGMIN -0.28 -4.79 -0.4 4.63e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs597539 0.652 rs604524 chr11:68629929 G/A cg06028808 chr11:68637592 NA 0.51 6.67 0.51 7.76e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs6748734 1.000 rs4311055 chr2:241821017 T/C cg04034577 chr2:241836375 C2orf54 -0.39 -6.2 -0.49 7.61e-9 Urinary metabolites; TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg22166914 chr1:53195759 ZYG11B 0.34 5.71 0.46 7.92e-8 Monocyte count; TGCT cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg11062466 chr8:58055876 NA -0.38 -4.62 -0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs7439150 0.954 rs4220 chr4:155491759 G/A cg22130008 chr4:155548532 NA -0.48 -5.79 -0.46 5.4e-8 Fibrinogen levels; TGCT cis rs57920188 0.513 rs4290031 chr1:4094701 A/G cg20703997 chr1:4087676 NA 0.48 5.77 0.46 5.97e-8 Interleukin-17 levels; TGCT cis rs13256369 0.802 rs12681925 chr8:8561649 G/A cg18904891 chr8:8559673 CLDN23 0.57 5.27 0.43 5.87e-7 Obesity-related traits; TGCT cis rs2197308 0.655 rs1971964 chr12:37870474 C/T cg26384229 chr12:38710491 ALG10B 0.89 7.94 0.58 1.06e-12 Morning vs. evening chronotype; TGCT cis rs427394 0.743 rs274716 chr5:6722289 T/C cg10857441 chr5:6722123 POLS -0.31 -7.2 -0.54 5.08e-11 Menopause (age at onset); TGCT cis rs7104764 1.000 rs6598063 chr11:243672 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs6951245 0.507 rs10227709 chr7:1180515 T/G cg18402987 chr7:1209562 NA 0.5 4.69 0.39 7.13e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11098499 0.954 rs11722872 chr4:120233030 G/C cg09307838 chr4:120376055 NA 0.63 5.84 0.46 4.34e-8 Corneal astigmatism; TGCT cis rs9926296 0.568 rs886950 chr16:89836872 T/C cg21285383 chr16:89894308 SPIRE2 0.44 6.89 0.53 2.46e-10 Vitiligo; TGCT cis rs7267979 1.000 rs6050544 chr20:25320228 T/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8032315 0.965 rs1894400 chr15:91428955 C/T cg03209642 chr15:91427605 FES 0.52 4.98 0.41 2.07e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs763121 0.853 rs5750649 chr22:39036769 T/C cg06022373 chr22:39101656 GTPBP1 0.8 8.25 0.6 1.95e-13 Menopause (age at onset); TGCT cis rs7267979 0.834 rs6115100 chr20:25225938 C/A cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7226408 0.857 rs2166294 chr18:34488534 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6125597 0.967 rs6067030 chr20:47884403 C/T cg11220565 chr20:47934802 NA -0.3 -4.61 -0.38 9.8e-6 Intelligence (multi-trait analysis); TGCT cis rs2997447 0.739 rs3008223 chr1:26389633 T/C cg19633962 chr1:26362018 EXTL1 -0.68 -4.7 -0.39 6.68e-6 QRS complex (12-leadsum); TGCT cis rs6570726 0.791 rs11155435 chr6:145938545 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.96 0.41 2.29e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs494003 0.951 rs11227283 chr11:65499022 C/T cg04293602 chr11:65553660 OVOL1 0.36 4.5 0.37 1.52e-5 Systemic lupus erythematosus; TGCT cis rs270601 0.817 rs460089 chr5:131629772 C/G cg24060327 chr5:131705240 SLC22A5 -0.71 -7.27 -0.55 3.58e-11 Acylcarnitine levels; TGCT cis rs4273100 0.688 rs28582509 chr17:19165179 T/C cg01534423 chr17:18965556 NA 0.8 7.26 0.55 3.79e-11 Schizophrenia; TGCT cis rs11190604 0.767 rs10883483 chr10:102174244 T/C cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs853679 0.517 rs17711801 chr6:28092307 C/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs6433895 0.961 rs6746347 chr2:182017374 T/G cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT cis rs12681287 0.605 rs6471296 chr8:87374654 A/G cg27223183 chr8:87520930 FAM82B 0.68 5.07 0.41 1.44e-6 Caudate activity during reward; TGCT cis rs12510870 0.566 rs16849727 chr4:74460744 A/C cg05868023 chr4:75230803 EREG 0.56 5.01 0.41 1.83e-6 Iris color (b* coordinate); TGCT cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg12379764 chr21:47803548 PCNT 0.5 5.13 0.42 1.08e-6 Testicular germ cell tumor; TGCT cis rs7666738 1.000 rs13116475 chr4:99054843 C/T cg05340658 chr4:99064831 C4orf37 -0.47 -4.65 -0.39 8.52e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2486288 0.656 rs6493143 chr15:45570781 G/T cg14582100 chr15:45693742 SPATA5L1 -0.43 -4.86 -0.4 3.48e-6 Glomerular filtration rate; TGCT cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg23758822 chr17:41437982 NA -0.57 -6.0 -0.47 2.05e-8 Menopause (age at onset); TGCT cis rs9910055 0.659 rs721769 chr17:42261588 T/G cg19774624 chr17:42201019 HDAC5 -0.87 -10.64 -0.69 3.55e-19 Total body bone mineral density; TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg11494091 chr17:61959527 GH2 0.61 14.78 0.8 4.02e-29 Prudent dietary pattern; TGCT cis rs2404602 0.716 rs7179142 chr15:76698268 G/A cg22467129 chr15:76604101 ETFA -0.57 -7.0 -0.53 1.39e-10 Blood metabolite levels; TGCT cis rs6460942 0.778 rs76030612 chr7:12462937 C/A cg06484146 chr7:12443880 VWDE -0.53 -5.59 -0.45 1.36e-7 Coronary artery disease; TGCT cis rs11077998 0.840 rs9894993 chr17:80481088 T/C cg10255544 chr17:80519551 FOXK2 0.24 4.79 0.39 4.76e-6 Reticulocyte fraction of red cells; TGCT cis rs904251 0.600 rs4714068 chr6:37455642 A/C cg08126542 chr6:37504118 NA -0.41 -5.98 -0.47 2.24e-8 Cognitive performance; TGCT cis rs6969780 0.841 rs10246712 chr7:27198860 C/T cg04321618 chr7:27170880 HOXA4 0.54 4.93 0.4 2.55e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs4654899 0.680 rs10916885 chr1:21188703 A/T cg01072550 chr1:21505969 NA 0.55 8.93 0.63 4.85e-15 Superior frontal gyrus grey matter volume; TGCT cis rs11098499 0.909 rs79704848 chr4:120309351 T/A cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs904251 0.828 rs1757178 chr6:37486310 C/T cg01843034 chr6:37503916 NA 0.51 6.11 0.48 1.16e-8 Cognitive performance; TGCT trans rs2688608 0.672 rs4065 chr10:75676464 C/T cg13918328 chr10:52500089 ASAH2B 0.68 6.76 0.52 4.94e-10 Inflammatory bowel disease; TGCT cis rs2816062 0.735 rs2816045 chr1:18892999 A/G cg18795169 chr1:18902165 NA -0.58 -13.28 -0.77 1.36e-25 Urate levels in lean individuals; TGCT cis rs12477438 0.765 rs1115756 chr2:99659845 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg16325326 chr1:53192061 ZYG11B 0.5 5.56 0.45 1.56e-7 Monocyte count; TGCT cis rs8014204 0.804 rs35769520 chr14:75255115 G/A cg06637938 chr14:75390232 RPS6KL1 0.7 6.77 0.52 4.47e-10 Caffeine consumption; TGCT cis rs6547741 0.816 rs7560847 chr2:27882700 A/G cg27432699 chr2:27873401 GPN1 -0.24 -6.06 -0.48 1.5e-8 Oral cavity cancer; TGCT trans rs2727020 0.576 rs12293522 chr11:49558425 T/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.12 -0.54 7.81e-11 Coronary artery disease; TGCT cis rs1903068 0.785 rs10013228 chr4:55997340 A/G cg09978860 chr4:56023921 NA 0.55 6.09 0.48 1.31e-8 Endometriosis; TGCT cis rs1797081 0.811 rs1797076 chr10:16853076 A/G cg23933602 chr10:16859644 RSU1 0.88 10.22 0.68 3.67e-18 Platelet distribution width; TGCT cis rs6725041 0.846 rs10185271 chr2:213089454 T/G cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs9906944 0.707 rs9916472 chr17:47109998 C/T cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs12477438 0.871 rs62156364 chr2:99695097 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -4.45 -0.37 1.9e-5 Chronic sinus infection; TGCT cis rs7267979 0.899 rs2104734 chr20:25526668 A/G cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.649 rs5758466 chr22:42176059 G/A cg06481639 chr22:41940642 POLR3H 0.53 4.54 0.38 1.29e-5 Vitiligo; TGCT cis rs9872999 1 rs9872999 chr3:133457514 C/T cg16262614 chr3:133464971 TF 0.34 4.62 0.38 9.28e-6 Iron status biomarkers; TGCT cis rs4906332 1.000 rs4906327 chr14:103929039 C/T cg26031613 chr14:104095156 KLC1 -0.53 -4.71 -0.39 6.62e-6 Coronary artery disease; TGCT cis rs727505 0.754 rs55723877 chr7:124780899 T/A cg23710748 chr7:124431027 NA -0.25 -4.44 -0.37 1.97e-5 Lewy body disease; TGCT cis rs611744 0.967 rs652485 chr8:109202696 G/A cg21045802 chr8:109455806 TTC35 0.5 4.54 0.38 1.33e-5 Dupuytren's disease; TGCT cis rs3733631 1.000 rs3775971 chr4:104641920 C/T cg24090629 chr4:104641072 TACR3 0.74 6.05 0.48 1.6e-8 Menarche (age at onset); TGCT cis rs7666738 0.819 rs62318904 chr4:99036101 A/T cg05340658 chr4:99064831 C4orf37 0.51 5.69 0.45 8.74e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12541335 0.639 rs4872468 chr8:22179844 G/C cg02463440 chr8:22132932 PIWIL2 0.26 5.17 0.42 9.05e-7 Hypertriglyceridemia; TGCT cis rs61990749 0.597 rs2267759 chr14:78147615 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.65 -0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs75686122 0.892 rs77472944 chr8:104697477 G/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7829975 0.564 rs2976855 chr8:8301794 G/A cg08975724 chr8:8085496 FLJ10661 0.6 5.75 0.46 6.63e-8 Mood instability; TGCT cis rs711245 0.572 rs3821150 chr2:36795233 G/A cg01206211 chr2:36825736 FEZ2 0.38 5.78 0.46 5.66e-8 Height; TGCT cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg19318889 chr4:1322082 MAEA 0.19 5.05 0.41 1.54e-6 Longevity; TGCT cis rs74181299 1.000 rs74181299 chr2:65283972 T/C cg05010058 chr2:65284262 CEP68 0.43 4.82 0.4 4.11e-6 Pulse pressure; TGCT cis rs72949976 0.584 rs13001511 chr2:214025262 G/A cg08319019 chr2:214017104 IKZF2 0.84 8.38 0.6 9.58e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs12497850 0.931 rs9840684 chr3:48893780 T/C cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT trans rs2688608 0.836 rs2675668 chr10:75636148 G/A cg13918328 chr10:52500089 ASAH2B 0.66 6.92 0.53 2.18e-10 Inflammatory bowel disease; TGCT cis rs4690686 0.500 rs7683662 chr4:177272004 A/T cg17059388 chr4:177262070 NA 0.28 4.51 0.38 1.46e-5 Essential tremor; TGCT cis rs7017914 0.935 rs2732093 chr8:71919079 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs858239 0.539 rs4504540 chr7:23186198 C/G cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7666738 0.830 rs3896704 chr4:99034252 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11626933 1.000 rs2236402 chr14:90734378 C/G cg14092571 chr14:90743983 NA -0.3 -5.77 -0.46 6.02e-8 Gut microbiota (bacterial taxa); TGCT cis rs7772486 0.686 rs857882 chr6:145969716 T/G cg05347473 chr6:146136440 FBXO30 -0.49 -4.59 -0.38 1.06e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2204008 0.837 rs11168504 chr12:37964922 G/T cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT trans rs6089829 0.962 rs4997812 chr20:61663153 T/G cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs67340775 0.541 rs200965 chr6:27866384 G/A cg26587870 chr6:27730563 NA -0.31 -4.47 -0.37 1.77e-5 Lung cancer in ever smokers; TGCT cis rs9303542 0.625 rs8072250 chr17:46569216 C/T cg25032089 chr17:46643351 HOXB3 0.5 5.5 0.44 2.03e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT trans rs916888 0.610 rs199530 chr17:44836653 C/T cg10053473 chr17:62856997 LRRC37A3 0.39 6.72 0.52 5.98e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4631830 0.863 rs2611508 chr10:51518047 T/A cg10326726 chr10:51549505 MSMB -0.26 -5.03 -0.41 1.68e-6 Prostate-specific antigen levels; TGCT cis rs2637266 1.000 rs6480824 chr10:78355705 G/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs1018836 0.884 rs13279263 chr8:91648780 T/C cg16814680 chr8:91681699 NA -0.84 -8.77 -0.62 1.15e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.505 rs405208 chr1:53176674 C/T cg08859206 chr1:53392774 SCP2 -0.36 -5.13 -0.42 1.1e-6 Monocyte count; TGCT cis rs7017914 0.935 rs3110258 chr8:71938532 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs7246657 0.722 rs8103647 chr19:38100452 C/A cg03611452 chr19:38183253 ZNF781 0.59 4.72 0.39 6.14e-6 Coronary artery calcification; TGCT cis rs4824093 0.541 rs8142132 chr22:50211294 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -0.97 -5.07 -0.41 1.42e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 2.93e-27 Menopause (age at onset); TGCT cis rs11190604 0.767 rs11190509 chr10:102156208 G/A cg16342193 chr10:102329863 NA -0.39 -5.06 -0.41 1.49e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4819052 0.851 rs2838826 chr21:46655785 A/G cg06618935 chr21:46677482 NA -0.33 -5.37 -0.43 3.71e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs155076 0.938 rs485361 chr13:21845826 G/T cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs1801251 1.000 rs4973055 chr2:233720283 G/T cg08000102 chr2:233561755 GIGYF2 -0.64 -6.43 -0.5 2.46e-9 Coronary artery disease; TGCT cis rs644799 0.965 rs566877 chr11:95528045 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4455778 0.659 rs7782271 chr7:49057494 G/A cg26309511 chr7:48887640 NA 0.44 5.12 0.42 1.13e-6 Lung cancer in never smokers; TGCT trans rs10435719 0.647 rs10092605 chr8:11787395 T/G cg15556689 chr8:8085844 FLJ10661 0.78 7.32 0.55 2.78e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs13082711 0.554 rs7635958 chr3:27385616 A/C cg02860705 chr3:27208620 NA 0.43 6.05 0.48 1.6e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs6977660 0.714 rs12700077 chr7:19791607 A/G cg05791153 chr7:19748676 TWISTNB -0.8 -4.52 -0.38 1.44e-5 Thyroid stimulating hormone; TGCT cis rs7432375 0.610 rs6793936 chr3:136509793 A/C cg15507776 chr3:136538369 TMEM22 0.55 5.64 0.45 1.1e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9916302 0.904 rs4795384 chr17:37716771 C/G cg15445000 chr17:37608096 MED1 0.35 5.1 0.42 1.25e-6 Glomerular filtration rate (creatinine); TGCT cis rs10751667 0.666 rs7483273 chr11:951127 T/C cg06064525 chr11:970664 AP2A2 -0.35 -7.98 -0.58 8.36e-13 Alzheimer's disease (late onset); TGCT cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg11941060 chr3:133502564 NA -0.31 -6.56 -0.51 1.32e-9 Iron status biomarkers; TGCT trans rs797680 0.786 rs10874772 chr1:93787770 G/A cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7681423 1.000 rs7681423 chr4:155542248 C/T cg20735720 chr4:155535218 FGG -0.46 -6.8 -0.52 3.99e-10 Fibrinogen; TGCT cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.520 rs11695751 chr2:99708247 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.22 0.85 7.28e-37 Chronic sinus infection; TGCT cis rs3008870 0.920 rs12132532 chr1:67457015 G/T cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg17054783 chr10:134559939 INPP5A -0.25 -5.06 -0.41 1.45e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs13191362 1.000 rs35593345 chr6:163174981 G/C cg21926612 chr6:163149169 PACRG;PARK2 1.11 8.17 0.59 2.98e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs17125944 0.505 rs77949716 chr14:53204234 G/A cg00686598 chr14:53173677 PSMC6 1.09 5.66 0.45 1e-7 Alzheimer's disease (late onset); TGCT cis rs9911578 0.967 rs11656413 chr17:57082013 A/C cg12560992 chr17:57184187 TRIM37 -0.78 -9.58 -0.65 1.35e-16 Intelligence (multi-trait analysis); TGCT cis rs17608059 0.504 rs11656981 chr17:13978777 A/G cg11395062 chr17:14139857 CDRT15 0.47 6.56 0.51 1.3e-9 Temperament; TGCT cis rs782590 0.967 rs4290693 chr2:55799991 C/G cg18811423 chr2:55921094 PNPT1 0.66 7.0 0.53 1.39e-10 Metabolic syndrome; TGCT cis rs1372520 0.935 rs1372519 chr4:90757309 A/G cg14346243 chr4:90757452 SNCA -0.64 -5.24 -0.43 6.59e-7 Neuroticism; TGCT cis rs1801251 1.000 rs4973054 chr2:233710713 G/C cg08000102 chr2:233561755 GIGYF2 -0.63 -6.46 -0.5 2.2e-9 Coronary artery disease; TGCT cis rs11577318 0.853 rs4450008 chr1:26643860 C/A cg04990556 chr1:26633338 UBXN11 -0.57 -4.94 -0.41 2.51e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6684514 0.961 rs12029695 chr1:156299847 C/T cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10479542 0.896 rs10078712 chr5:178978805 C/T cg21226059 chr5:178986404 RUFY1 -0.47 -4.91 -0.4 2.79e-6 Lung cancer; TGCT cis rs4851313 0.527 rs10183150 chr2:100939117 A/G cg14675211 chr2:100938903 LONRF2 0.51 5.02 0.41 1.72e-6 Intelligence (multi-trait analysis); TGCT trans rs1415174 0.958 rs1415173 chr1:87850592 C/T cg23065576 chr20:25207247 ENTPD6 0.27 6.9 0.53 2.33e-10 Breast cancer; TGCT cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs1577917 0.771 rs2842612 chr6:86303091 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs7666738 0.924 rs11097592 chr4:98927532 C/T cg17366294 chr4:99064904 C4orf37 0.77 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10782582 0.593 rs11163967 chr1:76154185 T/C cg03433033 chr1:76189801 ACADM -0.65 -7.41 -0.55 1.67e-11 Daytime sleep phenotypes; TGCT cis rs587847 0.767 rs12148402 chr15:37651465 G/T cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.86e-5 Intraocular pressure; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg11235426 chr6:292522 DUSP22 0.66 6.84 0.52 3.2e-10 Menopause (age at onset); TGCT cis rs4252435 0.614 rs4252393 chr7:142628482 C/G cg21621906 chr7:142494914 NA 0.92 4.45 0.37 1.87e-5 Cancer; TGCT cis rs3812049 0.826 rs17764730 chr5:127357526 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.59 5.34 0.43 4.27e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs477895 0.838 rs12794145 chr11:64006484 C/T cg23719950 chr11:63933701 MACROD1 -0.69 -5.78 -0.46 5.66e-8 Mean platelet volume; TGCT cis rs10114408 0.921 rs7020529 chr9:96640224 G/A cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9646954 0.542 rs4149505 chr2:101033697 G/A cg08017756 chr2:100939284 LONRF2 -0.29 -4.53 -0.38 1.39e-5 Intelligence (multi-trait analysis); TGCT cis rs9457247 0.935 rs2757046 chr6:167374353 C/T cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.05e-6 Crohn's disease; TGCT cis rs6751439 0.765 rs2348537 chr2:154730020 T/C cg25703346 chr2:154729189 GALNT13 0.77 4.65 0.39 8.25e-6 Forced expiratory volume in 1 second (occupational environmental exposures interaction); TGCT cis rs2299587 0.554 rs3739404 chr8:17739843 C/A cg01800426 chr8:17659068 MTUS1 -0.56 -4.99 -0.41 1.97e-6 Economic and political preferences; TGCT cis rs782590 0.935 rs782652 chr2:55862775 C/A cg18811423 chr2:55921094 PNPT1 0.65 6.85 0.52 3.04e-10 Metabolic syndrome; TGCT cis rs2242116 0.796 rs4587 chr3:46963502 T/C cg02527881 chr3:46936655 PTH1R -0.33 -6.09 -0.48 1.29e-8 Birth weight; TGCT cis rs9399135 0.967 rs7766189 chr6:135353851 A/C cg24558204 chr6:135376177 HBS1L 0.48 4.77 0.39 5.14e-6 Red blood cell count; TGCT cis rs4927850 1.000 rs7614767 chr3:195753451 C/T cg22891161 chr3:195456627 MUC20 -0.2 -4.73 -0.39 5.98e-6 Pancreatic cancer; TGCT cis rs6977660 0.652 rs2072187 chr7:19747915 A/G cg07541023 chr7:19748670 TWISTNB 1.03 6.16 0.48 9.21e-9 Thyroid stimulating hormone; TGCT cis rs9911578 1.000 rs7215808 chr17:56940742 G/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs2806561 0.765 rs1738468 chr1:23510850 T/G cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs4819052 1.000 rs2838847 chr21:46670958 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.77 5.62 0.45 1.22e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs208515 0.525 rs12204452 chr6:66680325 C/T cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs7178572 0.568 rs4886850 chr15:77404160 G/C cg22256960 chr15:77711686 NA -0.86 -8.84 -0.62 8.05e-15 Type 2 diabetes; TGCT cis rs9818758 0.607 rs71324929 chr3:49044713 C/T cg00383909 chr3:49044727 WDR6 1.33 6.68 0.51 7.32e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs11096990 0.634 rs7659894 chr4:39284435 G/A cg20847110 chr4:39482781 LOC401127 -0.17 -4.58 -0.38 1.12e-5 Cognitive function; TGCT cis rs9400467 0.500 rs1361425 chr6:111472243 A/T cg15721981 chr6:111408429 SLC16A10 -0.53 -4.67 -0.39 7.84e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs477895 0.838 rs72922039 chr11:64013116 A/C cg23719950 chr11:63933701 MACROD1 -0.69 -5.77 -0.46 5.92e-8 Mean platelet volume; TGCT cis rs17761864 0.579 rs12452074 chr17:2051730 G/T cg02171503 chr17:1588363 PRPF8 -0.48 -4.64 -0.38 8.86e-6 Esophageal cancer (squamous cell); TGCT cis rs35160687 0.814 rs6547673 chr2:86528938 A/G cg12542933 chr2:85804724 VAMP8 0.38 4.46 0.37 1.79e-5 Night sleep phenotypes; TGCT cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs12464483 0.524 rs2602772 chr2:30885263 C/A cg17749961 chr2:30669863 LCLAT1 0.59 4.69 0.39 7.22e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs6500602 0.893 rs6500598 chr16:4470964 G/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.31 0.49 4.45e-9 Schizophrenia; TGCT cis rs7786808 0.579 rs12669482 chr7:158188813 G/A cg01191920 chr7:158217561 PTPRN2 -0.36 -5.38 -0.43 3.65e-7 Obesity-related traits; TGCT cis rs7945705 0.520 rs1984791 chr11:9035027 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.45 4.99 0.41 1.97e-6 Hemoglobin concentration; TGCT cis rs28374715 0.662 rs1554445 chr15:41503198 A/C cg18705301 chr15:41695430 NDUFAF1 -0.77 -10.97 -0.7 5.4e-20 Ulcerative colitis; TGCT cis rs7954584 0.504 rs10840633 chr12:122377511 A/T cg21016266 chr12:122356598 WDR66 0.51 6.29 0.49 4.93e-9 Mean corpuscular volume; TGCT cis rs4595586 0.525 rs7968566 chr12:39377200 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT trans rs1005277 0.522 rs9418276 chr10:37940116 G/T cg17830980 chr10:43048298 ZNF37B -0.67 -7.46 -0.56 1.32e-11 Extrinsic epigenetic age acceleration; TGCT cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg00684032 chr4:1343700 KIAA1530 0.23 4.8 0.4 4.53e-6 Obesity-related traits; TGCT cis rs1691799 0.899 rs903587 chr12:66746061 C/A cg16791601 chr12:66731901 HELB -0.28 -6.18 -0.49 8.52e-9 White blood cell count (basophil); TGCT cis rs2288884 0.945 rs78336183 chr19:52561483 C/T cg13540795 chr19:52551618 ZNF432 -0.54 -4.83 -0.4 4.02e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs8054556 0.740 rs12716975 chr16:29950829 C/T cg26859862 chr16:30389551 SEPT1 -0.54 -4.71 -0.39 6.64e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7917772 0.560 rs11595170 chr10:104339851 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.46 -0.44 2.51e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs910316 0.763 rs1548807 chr14:75479582 T/G cg08847533 chr14:75593920 NEK9 0.83 8.89 0.62 5.99e-15 Height; TGCT cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs4850410 0.581 rs6434900 chr2:197910432 C/A cg19149314 chr2:197065128 HECW2 0.23 4.57 0.38 1.14e-5 Interferon alpha levels in systemic lupus erythematosus; TGCT cis rs2115630 0.967 rs11073731 chr15:85355113 C/A cg11189052 chr15:85197271 WDR73 -0.65 -6.29 -0.49 4.99e-9 P wave terminal force; TGCT trans rs11764590 0.950 rs11514731 chr7:2051503 C/G cg10840412 chr1:235813424 GNG4 0.96 6.93 0.53 1.99e-10 Neuroticism; TGCT cis rs651907 0.557 rs35117343 chr3:101445126 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.21 0.68 3.89e-18 Colorectal cancer; TGCT cis rs3796352 1.000 rs7645611 chr3:53125297 G/C cg07884673 chr3:53033167 SFMBT1 0.53 5.68 0.45 8.87e-8 Immune reponse to smallpox (secreted IL-2); TGCT trans rs1496653 0.602 rs35230557 chr3:23386956 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2456568 0.570 rs1518579 chr11:93656821 A/G cg17595323 chr11:93583763 C11orf90 -0.46 -5.77 -0.46 5.83e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3026101 0.624 rs1058383 chr17:5288203 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.63 0.38 9.15e-6 Body mass index; TGCT cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg07424592 chr7:64974309 NA 1.32 8.0 0.58 7.51e-13 Diabetic kidney disease; TGCT cis rs9486719 0.948 rs2499813 chr6:96875338 T/C cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs904251 0.504 rs9380677 chr6:37480366 A/G cg01843034 chr6:37503916 NA -0.56 -7.35 -0.55 2.36e-11 Cognitive performance; TGCT cis rs12908161 1.000 rs35630683 chr15:85349231 T/C cg12863693 chr15:85201151 NMB 0.42 5.06 0.41 1.5e-6 Schizophrenia; TGCT cis rs7772486 0.764 rs2265468 chr6:146218346 A/C cg05347473 chr6:146136440 FBXO30 0.51 5.0 0.41 1.95e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs75686122 0.892 rs76748895 chr8:104641510 A/G cg04852977 chr8:104510831 NA 0.59 4.48 0.37 1.67e-5 Cocaine dependence; TGCT cis rs12210905 1.000 rs12205628 chr6:27225959 C/A cg08851530 chr6:28072375 NA 1.06 5.05 0.41 1.55e-6 Hip circumference adjusted for BMI; TGCT cis rs7681423 1.000 rs2066864 chr4:155525695 G/A cg20735720 chr4:155535218 FGG -0.46 -6.8 -0.52 4e-10 Fibrinogen; TGCT cis rs250677 0.687 rs250666 chr5:148454622 A/G cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs377070 0.816 rs309400 chr4:123616189 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.42 4.65 0.39 8.39e-6 Mosquito bite size; TGCT cis rs1008375 1.000 rs1008374 chr4:17683219 G/A cg18681998 chr4:17616180 MED28 0.88 10.22 0.68 3.66e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7119 0.651 rs12904533 chr15:77845928 G/A cg27398640 chr15:77910606 LINGO1 -0.28 -5.2 -0.42 7.98e-7 Type 2 diabetes; TGCT cis rs2147959 0.766 rs2182200 chr1:228716166 C/A cg22700015 chr1:228743131 NA -0.61 -5.15 -0.42 9.77e-7 Adult asthma; TGCT cis rs4563143 0.704 rs16961809 chr19:29226299 C/T cg12756686 chr19:29218302 NA 0.72 6.9 0.53 2.32e-10 Methadone dose in opioid dependence; TGCT cis rs7752195 0.643 rs76266945 chr6:25240510 G/A cg16898833 chr6:26189333 HIST1H4D 1.17 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7216064 1.000 rs12602655 chr17:65909442 A/G cg12091567 chr17:66097778 LOC651250 -0.81 -6.06 -0.48 1.53e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9326248 0.954 rs8521 chr11:117067699 C/T cg26566898 chr11:117069891 TAGLN 0.36 5.08 0.42 1.33e-6 Blood protein levels; TGCT cis rs981844 0.961 rs17299034 chr4:154671396 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs886126 0.684 rs3858704 chr12:111705893 A/G cg10833066 chr12:111807467 FAM109A 0.37 6.58 0.51 1.2e-9 Coronary heart disease; TGCT trans rs11722228 0.522 rs12504600 chr4:10067138 C/A cg26043149 chr18:55253948 FECH 1.1 10.53 0.69 6.47e-19 Gout;Urate levels;Serum uric acid levels; TGCT cis rs9326248 1.000 rs664082 chr11:117071070 C/G cg11861562 chr11:117069780 TAGLN 0.27 4.48 0.37 1.69e-5 Blood protein levels; TGCT cis rs6752107 1.000 rs2241878 chr2:234183718 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.79 0.39 4.74e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7178424 0.516 rs2414758 chr15:62327127 T/C cg00456672 chr15:62358751 C2CD4A -0.29 -4.46 -0.37 1.84e-5 Height; TGCT cis rs4665809 0.590 rs10179959 chr2:26426403 G/A cg25036284 chr2:26402008 FAM59B -0.6 -4.84 -0.4 3.83e-6 Gut microbiome composition (summer); TGCT cis rs12681287 0.752 rs34279109 chr8:87247944 G/A cg27223183 chr8:87520930 FAM82B -0.83 -5.76 -0.46 6.33e-8 Caudate activity during reward; TGCT cis rs524281 0.861 rs11227409 chr11:65870938 A/G cg00563793 chr11:65837595 PACS1 0.55 4.62 0.38 9.44e-6 Electroencephalogram traits; TGCT cis rs12681288 0.862 rs34510005 chr8:1018943 T/C cg21347738 chr8:1310380 NA -0.22 -4.43 -0.37 2.01e-5 Schizophrenia; TGCT cis rs13217239 0.646 rs7768407 chr6:27016795 G/A cg05738196 chr6:26577821 NA 0.53 5.22 0.42 7.24e-7 Schizophrenia; TGCT trans rs7618501 0.522 rs73077175 chr3:49774658 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.8 -7.32 -0.55 2.74e-11 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.609 rs12699449 chr7:1951227 G/C cg04267008 chr7:1944627 MAD1L1 -0.36 -4.6 -0.38 1.03e-5 Bipolar disorder and schizophrenia; TGCT cis rs7647973 0.710 rs7629322 chr3:49621994 C/T cg05785598 chr3:49045655 WDR6 0.4 4.62 0.38 9.42e-6 Menarche (age at onset); TGCT cis rs7216064 0.684 rs7406031 chr17:66021753 C/T cg12091567 chr17:66097778 LOC651250 1.07 8.8 0.62 9.68e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1799949 0.965 rs11656945 chr17:41330265 A/G cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs729982 1 rs729982 chr22:40810946 T/C cg07138101 chr22:40742427 ADSL 0.78 5.29 0.43 5.4e-7 Number of common colds; TGCT cis rs34467563 1.000 rs34467563 chr8:97416907 C/T cg15747595 chr8:98289880 TSPYL5 -0.42 -4.57 -0.38 1.15e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9443645 0.810 rs10943613 chr6:79745107 C/T cg09184832 chr6:79620586 NA -0.45 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs7103648 0.897 rs2278890 chr11:47399602 G/A cg20307385 chr11:47447363 PSMC3 1.05 12.13 0.74 8.16e-23 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs11190604 1.000 rs28522614 chr10:102323141 T/A cg16342193 chr10:102329863 NA -0.41 -5.15 -0.42 9.86e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7010267 0.543 rs6469796 chr8:120018042 G/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs79349575 0.783 rs1994970 chr17:47014127 C/T cg07967210 chr17:47022446 SNF8 -0.39 -5.46 -0.44 2.53e-7 Type 2 diabetes; TGCT cis rs17345786 0.906 rs55710435 chr3:101180330 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs769267 0.965 rs13964 chr19:19468710 C/G cg02546618 chr19:19431379 KIAA0892;SF4 -0.63 -5.13 -0.42 1.07e-6 Tonsillectomy; TGCT cis rs4808199 0.842 rs11085259 chr19:19445856 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.33 0.43 4.49e-7 Nonalcoholic fatty liver disease; TGCT cis rs9388451 0.872 rs2008027 chr6:126052359 A/G cg10911889 chr6:126070802 HEY2 0.51 5.14 0.42 1.03e-6 Brugada syndrome; TGCT cis rs8077577 0.895 rs13284 chr17:18112130 C/T cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs4595586 0.545 rs7310463 chr12:39368927 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs112217694 1.000 rs80123509 chr4:104651589 A/C cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs13188771 0.690 rs350560 chr5:100857718 C/T cg10455971 chr5:101119566 NA -0.44 -4.52 -0.38 1.44e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs1005277 0.579 rs2474608 chr10:38457109 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.23 -0.59 2.17e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1887596 0.705 rs9551301 chr13:27237134 G/A cg01312412 chr13:27282625 NA 0.28 4.91 0.4 2.83e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs2239547 0.657 rs2072391 chr3:52862200 C/T cg11645453 chr3:52864694 ITIH4 0.34 5.67 0.45 9.34e-8 Schizophrenia; TGCT cis rs3008870 0.959 rs56707923 chr1:67388016 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg03161606 chr19:29218774 NA 0.59 5.71 0.46 7.95e-8 Methadone dose in opioid dependence; TGCT cis rs4901869 0.931 rs12891570 chr14:59334338 T/A cg02291164 chr14:59296302 NA 0.24 4.58 0.38 1.11e-5 Panic disorder; TGCT cis rs28595532 0.920 rs114057512 chr4:119750179 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs17268829 1.000 rs17321542 chr7:94103352 A/G cg06439941 chr7:93550756 GNG11 -0.23 -4.47 -0.37 1.75e-5 Breast cancer; TGCT cis rs7666738 0.830 rs6823718 chr4:99063202 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.583 rs4413022 chr17:17858280 G/C cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs6692209 1 rs6692209 chr1:152506444 C/T cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.26e-9 Plantar warts; TGCT cis rs2562456 0.833 rs2681388 chr19:21732253 G/C cg25650185 chr19:21324782 ZNF431 -0.64 -5.73 -0.46 7.12e-8 Pain; TGCT cis rs9527 0.545 rs12784384 chr10:104957594 G/C cg04362960 chr10:104952993 NT5C2 0.68 5.73 0.46 7.14e-8 Arsenic metabolism; TGCT cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.85 -6.05 -0.48 1.57e-8 Gut microbiome composition (summer); TGCT cis rs72781680 1.000 rs72781683 chr2:24247423 T/C cg08917208 chr2:24149416 ATAD2B 0.82 5.02 0.41 1.75e-6 Lymphocyte counts; TGCT cis rs7412746 0.658 rs10305711 chr1:150802996 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.65 0.39 8.51e-6 Melanoma; TGCT cis rs1552244 0.882 rs35056669 chr3:10014171 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.5 0.44 2.05e-7 Alzheimer's disease; TGCT cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg11941060 chr3:133502564 NA 0.3 6.67 0.51 7.61e-10 Iron status biomarkers; TGCT cis rs5167 0.536 rs1882752 chr19:45461342 G/C cg13119609 chr19:45449297 APOC2 0.23 4.67 0.39 7.7e-6 Blood protein levels; TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg24503407 chr1:205819492 PM20D1 0.58 7.84 0.58 1.72e-12 Menarche (age at onset); TGCT cis rs2153535 0.601 rs9505451 chr6:8469950 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.765 rs6722164 chr2:99561527 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -7.06 -0.54 1.04e-10 Chronic sinus infection; TGCT cis rs2832191 0.703 rs2853827 chr21:30443596 T/C cg08807101 chr21:30365312 RNF160 0.65 6.14 0.48 1.01e-8 Dental caries; TGCT cis rs2404602 0.716 rs1588961 chr15:76752698 A/G cg26408565 chr15:76604113 ETFA -0.4 -5.26 -0.43 6.23e-7 Blood metabolite levels; TGCT cis rs892961 0.806 rs312910 chr17:75413961 A/C cg05865280 chr17:75406074 SEPT9 0.27 6.52 0.51 1.56e-9 Airflow obstruction; TGCT cis rs9436747 0.567 rs10889565 chr1:66053489 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.68 0.39 7.45e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs17376456 0.825 rs13165400 chr5:93091427 G/A cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs6490294 0.799 rs11066080 chr12:112350404 T/A cg10833066 chr12:111807467 FAM109A 0.36 5.41 0.44 3.18e-7 Mean platelet volume; TGCT cis rs1348850 0.831 rs1345139 chr2:178449791 G/T cg22681709 chr2:178499509 PDE11A -0.38 -4.5 -0.37 1.56e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs8013055 0.846 rs10136015 chr14:105973469 A/C cg19700328 chr14:106028568 NA -0.53 -5.91 -0.47 3.03e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs889312 0.500 rs832570 chr5:56156408 G/A cg24531977 chr5:56204891 C5orf35 -0.51 -5.19 -0.42 8.42e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs992157 0.560 rs4674274 chr2:219089131 A/T cg00012203 chr2:219082015 ARPC2 -0.81 -9.36 -0.64 4.37e-16 Colorectal cancer; TGCT cis rs9926296 0.605 rs7205053 chr16:89856763 G/C cg26513180 chr16:89883248 FANCA 1.06 14.86 0.8 2.56e-29 Vitiligo; TGCT cis rs1158570 0.564 rs2554372 chr8:131333913 A/G cg16277922 chr8:131349729 ASAP1 0.46 6.47 0.5 2.02e-9 Platelet count; TGCT cis rs7809950 0.798 rs2701684 chr7:107299527 C/T cg23024343 chr7:107201750 COG5 0.27 4.49 0.37 1.63e-5 Coronary artery disease; TGCT cis rs13082711 0.954 rs67282221 chr3:27552752 T/A cg02860705 chr3:27208620 NA 0.33 4.56 0.38 1.21e-5 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs9311474 0.502 rs4687624 chr3:52563572 C/T cg07507251 chr3:52567010 NT5DC2 0.46 6.53 0.51 1.51e-9 Electroencephalogram traits; TGCT cis rs3751972 0.668 rs7224724 chr17:26216090 A/G cg02948944 chr17:26242737 NA 0.33 4.79 0.4 4.63e-6 Fractional exhaled nitric oxide (childhood); TGCT cis rs7552404 1.000 rs441109 chr1:76120430 T/G cg22875332 chr1:76189707 ACADM -0.8 -9.79 -0.66 4.2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3862435 0.572 rs74480504 chr15:90924025 T/C cg14166756 chr15:90894880 ZNF774 -0.32 -5.06 -0.41 1.49e-6 Response to exercise (triglyceride level interaction); TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg18110333 chr6:292329 DUSP22 -0.72 -7.76 -0.57 2.71e-12 Menopause (age at onset); TGCT cis rs9894429 0.682 rs7406360 chr17:79591545 G/A cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.98e-6 Eye color traits; TGCT cis rs72781680 1.000 rs12616985 chr2:24165511 A/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs78707713 0.560 rs35060419 chr10:71229539 A/G cg14388049 chr10:71211838 TSPAN15 -0.39 -4.64 -0.38 8.84e-6 Venous thromboembolism; TGCT cis rs1878931 0.624 rs28089 chr16:3446937 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.68 -5.28 -0.43 5.65e-7 Body mass index (adult); TGCT cis rs1801251 1.000 rs13008942 chr2:233594875 G/A cg25237894 chr2:233734115 C2orf82 0.33 6.02 0.48 1.82e-8 Coronary artery disease; TGCT trans rs208520 0.742 rs208454 chr6:66907783 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.93 -9.78 -0.66 4.3e-17 Exhaled nitric oxide output; TGCT cis rs2361718 0.501 rs11869566 chr17:78143248 T/C cg21238619 chr17:78079768 GAA -0.33 -4.44 -0.37 1.95e-5 Yeast infection; TGCT cis rs801193 0.844 rs7779971 chr7:66161790 T/C cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs7666738 0.830 rs6825211 chr4:98807698 A/T cg17366294 chr4:99064904 C4orf37 0.65 6.79 0.52 4.13e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11864453 0.713 rs7191127 chr16:72123992 G/T cg14768367 chr16:72042858 DHODH 0.5 4.8 0.4 4.5e-6 Fibrinogen levels; TGCT cis rs7824557 0.603 rs2250028 chr8:11213589 T/G cg21775007 chr8:11205619 TDH 0.63 5.89 0.47 3.35e-8 Retinal vascular caliber; TGCT cis rs7086627 0.515 rs6585994 chr10:82191643 A/G cg01528321 chr10:82214614 TSPAN14 0.56 5.05 0.41 1.54e-6 Post bronchodilator FEV1; TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg14893161 chr1:205819251 PM20D1 -0.52 -7.36 -0.55 2.19e-11 Menarche (age at onset); TGCT cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs9993613 0.875 rs4694501 chr4:73476315 C/T cg15102770 chr4:73434591 ADAMTS3 0.54 4.96 0.41 2.26e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs992157 0.698 rs6746089 chr2:219170377 A/G cg00012203 chr2:219082015 ARPC2 0.81 8.07 0.59 5.04e-13 Colorectal cancer; TGCT cis rs1862618 0.525 rs2662016 chr5:56269047 A/G cg12311346 chr5:56204834 C5orf35 0.75 6.81 0.52 3.83e-10 Initial pursuit acceleration; TGCT cis rs7089973 0.604 rs35319791 chr10:116602296 C/A cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7666738 0.791 rs28858828 chr4:98950442 C/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg11502198 chr6:26597334 ABT1 0.54 4.99 0.41 1.99e-6 Intelligence (multi-trait analysis); TGCT cis rs2404618 0.593 rs7815979 chr8:1484887 A/G cg13402656 chr8:1511478 DLGAP2 -0.35 -5.95 -0.47 2.5e-8 Lung cancer; TGCT cis rs826838 0.510 rs17523988 chr12:39222785 A/C cg26384229 chr12:38710491 ALG10B 0.64 5.18 0.42 8.89e-7 Heart rate; TGCT cis rs26868 0.690 rs26835 chr16:2237549 C/T cg26873644 chr16:2260806 C16orf79 -0.22 -4.59 -0.38 1.08e-5 Height; TGCT cis rs57221529 0.766 rs72703075 chr5:592819 C/T cg20362242 chr5:692897 TPPP 0.55 4.79 0.4 4.65e-6 Lung disease severity in cystic fibrosis; TGCT cis rs597539 0.617 rs598353 chr11:68635770 C/A cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs72615157 0.697 rs2056726 chr7:99780283 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.58 -4.59 -0.38 1.09e-5 Lung function (FEV1/FVC); TGCT cis rs7772486 0.754 rs697054 chr6:146003770 C/T cg05347473 chr6:146136440 FBXO30 0.53 5.09 0.42 1.28e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1348850 0.632 rs4470372 chr2:178505857 G/A cg22681709 chr2:178499509 PDE11A -0.52 -6.5 -0.5 1.77e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7647973 0.925 rs6446257 chr3:49253492 A/G cg07690219 chr3:49449608 TCTA;RHOA 0.54 4.6 0.38 1.03e-5 Menarche (age at onset); TGCT cis rs2836974 0.965 rs8134733 chr21:40683459 C/T cg11644478 chr21:40555479 PSMG1 1.0 9.54 0.65 1.68e-16 Cognitive function; TGCT cis rs9916302 0.904 rs634365 chr17:37436966 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -5.12 -0.42 1.14e-6 Glomerular filtration rate (creatinine); TGCT cis rs11585357 0.947 rs6666990 chr1:17611520 G/A cg08277548 chr1:17600880 PADI3 0.97 9.95 0.67 1.7e-17 Hair shape; TGCT cis rs4879913 0.768 rs7036505 chr9:35599066 T/C cg18130437 chr9:35658183 CCDC107;RMRP -0.5 -4.92 -0.4 2.74e-6 Electroencephalogram traits; TGCT cis rs7707921 0.541 rs10066167 chr5:81495445 C/T cg15871215 chr5:81402204 ATG10 0.25 4.97 0.41 2.22e-6 Breast cancer; TGCT cis rs709400 0.663 rs62007681 chr14:103884651 G/A cg26031613 chr14:104095156 KLC1 0.86 9.43 0.65 2.96e-16 Body mass index; TGCT cis rs6840360 0.615 rs6858483 chr4:152465509 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs7178572 0.568 rs12906708 chr15:77681444 A/G cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs7552404 1.000 rs11161515 chr1:76212559 C/T cg22875332 chr1:76189707 ACADM 0.76 9.2 0.64 1.1e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13326165 0.760 rs123602 chr3:52442354 C/G cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs8050907 0.744 rs13335503 chr16:4529028 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs9916302 0.861 rs8079590 chr17:37426201 T/C cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs763014 0.931 rs710925 chr16:633354 G/A cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs11122272 0.637 rs2808593 chr1:231524228 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs826838 0.967 rs2069211 chr12:39128892 C/T cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs9911578 0.741 rs2611776 chr17:56819636 G/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs6456156 0.755 rs4710182 chr6:167514061 G/A cg07741184 chr6:167504864 NA 0.22 4.51 0.38 1.48e-5 Primary biliary cholangitis; TGCT trans rs66573146 1.000 rs67405518 chr4:6965930 C/T cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs2832191 1.000 rs2832183 chr21:30482150 G/A cg24692254 chr21:30365293 RNF160 -0.83 -8.72 -0.62 1.56e-14 Dental caries; TGCT cis rs9583531 0.891 rs61969076 chr13:111391568 C/T cg24331049 chr13:111365604 ING1 -0.75 -5.25 -0.43 6.49e-7 Coronary artery disease; TGCT cis rs4478858 0.735 rs6679360 chr1:31817936 G/T cg00250761 chr1:31883323 NA -0.27 -4.9 -0.4 2.92e-6 Alcohol dependence; TGCT cis rs4642101 0.561 rs7638333 chr3:12806142 T/C cg05775895 chr3:12838266 CAND2 0.51 5.11 0.42 1.16e-6 QRS complex (12-leadsum); TGCT cis rs78487399 0.710 rs7567685 chr2:43668169 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg17178900 chr1:205818956 PM20D1 0.56 6.97 0.53 1.63e-10 Menarche (age at onset); TGCT cis rs28595532 0.920 rs56227053 chr4:119772460 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs2228479 0.702 rs17233176 chr16:89832751 G/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg07092213 chr7:1199455 ZFAND2A -0.41 -4.5 -0.37 1.53e-5 Longevity;Endometriosis; TGCT trans rs1814175 0.791 rs1722023 chr11:49908136 G/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs12989701 0.877 rs71414738 chr2:127876242 C/T cg08168897 chr2:127865431 BIN1 0.53 5.77 0.46 6.05e-8 Alzheimer's disease (late onset); TGCT cis rs7085104 0.700 rs6163 chr10:104596924 C/A cg15744005 chr10:104629667 AS3MT -0.42 -5.28 -0.43 5.69e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs2692947 0.702 rs7604842 chr2:96777340 C/T cg22654517 chr2:96458247 NA -0.22 -4.62 -0.38 9.34e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs8028182 0.501 rs7166281 chr15:75928192 G/T cg20655648 chr15:75932815 IMP3 -0.59 -5.09 -0.42 1.29e-6 Sudden cardiac arrest; TGCT cis rs11031096 0.678 rs61899754 chr11:4201312 A/T cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs2933343 0.700 rs883602 chr3:128653952 A/G cg11901034 chr3:128598214 ACAD9 -0.65 -6.08 -0.48 1.38e-8 IgG glycosylation; TGCT cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs6933660 0.721 rs2128945 chr6:151767907 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.95 -10.88 -0.7 9.21e-20 Menarche (age at onset); TGCT cis rs11249608 0.548 rs13161528 chr5:178452958 C/G cg01312482 chr5:178451176 ZNF879 -0.49 -4.76 -0.39 5.2e-6 Pubertal anthropometrics; TGCT cis rs6121246 0.909 rs6119720 chr20:30347568 T/G cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs9972944 0.756 rs6416949 chr17:63767219 A/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.24 -0.43 6.59e-7 Total body bone mineral density; TGCT cis rs3820928 0.845 rs7570869 chr2:227878818 A/C cg11843606 chr2:227700838 RHBDD1 -0.52 -4.62 -0.38 9.54e-6 Pulmonary function; TGCT cis rs11112613 0.713 rs12296355 chr12:105953321 C/A cg03607813 chr12:105948248 NA 0.47 5.72 0.46 7.49e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs9443645 0.901 rs9361488 chr6:79782874 T/C cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs7523050 0.643 rs7522324 chr1:109399644 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs78487399 0.808 rs7578597 chr2:43732823 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.84 -0.4 3.79e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4478037 0.822 rs4528891 chr3:33121392 G/T cg19404215 chr3:33155277 CRTAP 1.03 5.37 0.43 3.8e-7 Major depressive disorder; TGCT cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.12 -0.54 7.61e-11 Colorectal cancer; TGCT trans rs2760061 0.819 rs1745416 chr1:228204497 G/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.21 -0.54 4.89e-11 Diastolic blood pressure; TGCT cis rs60871478 0.636 rs56393680 chr7:885696 A/G cg15782153 chr7:917662 C7orf20 0.54 4.91 0.4 2.86e-6 Cerebrospinal P-tau181p levels; TGCT cis rs10754283 0.934 rs6661282 chr1:90119992 C/T cg03145924 chr1:90228473 NA -0.4 -4.51 -0.38 1.51e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7523273 1.000 rs34385765 chr1:207993637 A/G cg22525895 chr1:207977042 MIR29B2 -0.49 -8.55 -0.61 3.78e-14 Schizophrenia; TGCT cis rs950169 0.519 rs7237 chr15:85186577 C/T cg17173187 chr15:85201210 NMB 0.59 7.05 0.53 1.1e-10 Schizophrenia; TGCT cis rs3825199 0.515 rs2072593 chr12:93970026 T/C cg18151635 chr12:93972918 NA -0.19 -4.52 -0.38 1.41e-5 Height; TGCT cis rs185694 1.000 rs846495 chr13:30894250 T/C cg07600127 chr13:30881527 KATNAL1 -0.82 -6.64 -0.51 8.92e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs9549367 0.826 rs9549713 chr13:113905308 G/T cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs4478858 0.684 rs4949369 chr1:31723845 T/A cg07478791 chr1:31886160 SERINC2 -0.49 -4.92 -0.4 2.73e-6 Alcohol dependence; TGCT cis rs13191362 1.000 rs13209728 chr6:162997533 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7107174 1.000 rs11602622 chr11:78010830 A/G cg12700464 chr11:78128424 GAB2 -0.7 -4.86 -0.4 3.46e-6 Testicular germ cell tumor; TGCT trans rs1864729 0.901 rs1348184 chr8:98276912 C/G cg08679828 chr8:102218111 ZNF706 -1.09 -7.6 -0.56 6.34e-12 Estradiol plasma levels (breast cancer); TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg10150615 chr22:24372951 LOC391322 -1.0 -12.91 -0.76 1.1e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs72781680 0.898 rs72798064 chr2:23982832 T/C cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg13395646 chr4:1353034 KIAA1530 0.4 4.98 0.41 2.1e-6 Obesity-related traits; TGCT cis rs727563 0.635 rs5751149 chr22:42139501 A/G cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2075165 0.901 rs2274226 chr1:156314627 C/T cg20302342 chr1:156215951 PAQR6 -0.36 -5.38 -0.44 3.56e-7 Tonsillectomy; TGCT cis rs17376456 0.877 rs10059630 chr5:93459807 C/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs1483890 0.723 rs900670 chr3:69406781 G/A cg22125112 chr3:69402811 FRMD4B 0.29 4.71 0.39 6.53e-6 Resting heart rate; TGCT cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg20607798 chr8:58055168 NA 0.5 4.67 0.39 7.65e-6 Developmental language disorder (linguistic errors); TGCT cis rs6088580 0.634 rs6142159 chr20:32993035 G/A cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs4237845 0.537 rs9645819 chr12:58270063 T/C cg23860436 chr12:58378763 NA 0.33 4.56 0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs12908161 1.000 rs12908161 chr15:85207825 A/G cg17173187 chr15:85201210 NMB 0.59 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs4727027 0.868 rs10952799 chr7:148840772 C/T cg23583168 chr7:148888333 NA -0.72 -9.17 -0.64 1.31e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9682041 0.808 rs9875109 chr3:170064776 A/G cg01716527 chr3:170072769 NA -0.26 -4.92 -0.4 2.67e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs9644630 0.897 rs4921654 chr8:19359974 G/T cg01280390 chr8:19363452 CSGALNACT1 -0.27 -4.78 -0.39 4.89e-6 Oropharynx cancer; TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg16145915 chr7:1198662 ZFAND2A -0.59 -8.31 -0.6 1.38e-13 Longevity;Endometriosis; TGCT cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs7918232 0.830 rs7911024 chr10:27433636 A/C cg14442939 chr10:27389572 ANKRD26 0.72 5.35 0.43 4.16e-7 Breast cancer; TGCT cis rs250677 0.522 rs2217638 chr5:148364355 A/G cg18129178 chr5:148520854 ABLIM3 0.36 4.63 0.38 9.23e-6 Breast cancer; TGCT cis rs11792861 0.564 rs3816237 chr9:111718348 T/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.66 7.62 0.56 5.71e-12 Menarche (age at onset); TGCT cis rs35883536 0.528 rs1414414 chr1:101028907 T/C cg10298815 chr1:101004474 GPR88 0.25 4.7 0.39 6.82e-6 Monocyte count; TGCT cis rs9341808 0.667 rs2490241 chr6:80846342 T/C cg08355045 chr6:80787529 NA 0.32 5.38 0.43 3.6e-7 Sitting height ratio; TGCT cis rs763014 0.865 rs2018789 chr16:632051 T/C cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs7647973 1.000 rs74471041 chr3:49542543 T/G cg07636037 chr3:49044803 WDR6 -0.7 -5.73 -0.46 7.08e-8 Menarche (age at onset); TGCT cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs6722750 0.901 rs7567728 chr2:64411932 A/C cg22352474 chr2:64371530 PELI1 -0.55 -4.9 -0.4 2.98e-6 Neuroticism; TGCT cis rs476633 0.573 rs6492995 chr15:41529712 T/C cg18705301 chr15:41695430 NDUFAF1 -0.68 -8.54 -0.61 3.98e-14 Glomerular filtration rate (creatinine); TGCT cis rs4862750 1.000 rs4862750 chr4:187904043 C/T cg22105103 chr4:187893119 NA 0.31 4.44 0.37 1.98e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2652822 0.662 rs34367270 chr15:63410912 G/A cg12855773 chr15:63363890 TPM1 -0.16 -4.59 -0.38 1.05e-5 Metabolic traits; TGCT cis rs6951245 0.507 rs11763865 chr7:1194274 G/A cg27454412 chr7:1067447 C7orf50 0.51 4.61 0.38 9.99e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs854765 0.583 rs7207395 chr17:17819335 C/T cg09796270 chr17:17721594 SREBF1 0.27 5.55 0.45 1.69e-7 Total body bone mineral density; TGCT cis rs539096 0.872 rs573350 chr1:44057950 T/C cg12908607 chr1:44402522 ARTN -0.52 -5.36 -0.43 3.99e-7 Intelligence (multi-trait analysis); TGCT cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg13393036 chr8:95962371 TP53INP1 -0.52 -6.45 -0.5 2.21e-9 Type 2 diabetes; TGCT cis rs514406 0.825 rs487453 chr1:53271225 T/C cg08859206 chr1:53392774 SCP2 0.39 5.79 0.46 5.33e-8 Monocyte count; TGCT cis rs7666738 0.747 rs2865955 chr4:99040518 A/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.935 rs9390329 chr6:145828026 T/C cg23711669 chr6:146136114 FBXO30 0.7 6.46 0.5 2.12e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9787249 0.915 rs58589165 chr1:40213670 A/T cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs17376456 0.569 rs6556834 chr5:93123067 C/T cg25358565 chr5:93447407 FAM172A -0.76 -6.68 -0.51 7.23e-10 Diabetic retinopathy; TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs11792861 0.962 rs72607161 chr9:111792640 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.44 0.37 1.99e-5 Menarche (age at onset); TGCT cis rs9911578 0.967 rs11656413 chr17:57082013 A/C cg05425664 chr17:57184151 TRIM37 0.68 6.89 0.53 2.55e-10 Intelligence (multi-trait analysis); TGCT cis rs11997175 0.846 rs34860600 chr8:33761566 C/A ch.8.33884649F chr8:33765107 NA 0.32 4.72 0.39 6.33e-6 Body mass index; TGCT cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.526 rs7755237 chr6:145731852 T/C cg23711669 chr6:146136114 FBXO30 -0.61 -5.42 -0.44 3e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs10501293 0.746 rs7131154 chr11:43001206 A/G cg23728189 chr2:10470961 HPCAL1 -0.27 -6.72 -0.52 5.74e-10 Cognitive performance; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg18538332 chr22:24372958 LOC391322 1.02 13.19 0.76 2.24e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2839186 0.900 rs2839200 chr21:47709095 C/T cg13732083 chr21:47605072 C21orf56 0.34 4.47 0.37 1.74e-5 Testicular germ cell tumor; TGCT cis rs6570726 0.791 rs952406 chr6:145925616 C/A cg23711669 chr6:146136114 FBXO30 0.84 8.91 0.62 5.38e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs910316 1.000 rs12897094 chr14:75579416 C/T cg08847533 chr14:75593920 NEK9 0.95 10.61 0.69 4.09e-19 Height; TGCT cis rs459571 0.834 rs379417 chr9:136890704 G/A cg13789015 chr9:136890014 NCRNA00094 0.39 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs9388451 0.839 rs11154331 chr6:126111429 A/T cg10911889 chr6:126070802 HEY2 0.48 4.97 0.41 2.18e-6 Brugada syndrome; TGCT cis rs11098499 0.644 rs10012252 chr4:120559139 T/C cg09307838 chr4:120376055 NA 0.62 5.82 0.46 4.83e-8 Corneal astigmatism; TGCT cis rs7267979 1.000 rs6115168 chr20:25372891 C/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7211079 0.879 rs7221505 chr17:78128231 G/A cg09238746 chr17:78121135 EIF4A3 -0.73 -5.86 -0.47 3.82e-8 Myocardial infarction; TGCT cis rs3540 0.597 rs3539 chr15:91045419 G/T cg22089800 chr15:90895588 ZNF774 -0.76 -7.77 -0.57 2.55e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs4722585 0.605 rs3753098 chr7:26198040 C/T cg07876897 chr7:26191696 NFE2L3 -0.38 -5.14 -0.42 1.03e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs6088580 0.634 rs6088498 chr20:33020446 A/G cg08999081 chr20:33150536 PIGU 0.28 5.52 0.44 1.91e-7 Glomerular filtration rate (creatinine); TGCT cis rs12579753 1.000 rs17749267 chr12:82178308 A/G cg21231944 chr12:82153410 PPFIA2 0.34 4.5 0.37 1.54e-5 Resting heart rate; TGCT cis rs2535633 0.631 rs2581803 chr3:52994981 G/A cg11645453 chr3:52864694 ITIH4 -0.29 -5.36 -0.43 3.99e-7 Body mass index; TGCT cis rs9467773 0.967 rs6941022 chr6:26553531 T/C cg26531700 chr6:26746687 NA 0.48 4.72 0.39 6.37e-6 Intelligence (multi-trait analysis); TGCT cis rs11948739 0.501 rs4254896 chr5:130363499 C/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Pediatric bone mineral content (hip); TGCT cis rs1453308 0.766 rs1470860 chr2:237176943 T/A cg19324714 chr2:237145437 ASB18 0.59 5.22 0.42 7.18e-7 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs34366173 1 rs34366173 chr15:63998914 CTT/C cg12036633 chr15:63758958 NA -0.53 -4.64 -0.38 8.85e-6 Reticulocyte fraction of red cells; TGCT cis rs6582630 0.679 rs7301806 chr12:38596667 G/A cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1609391 0.567 rs835633 chr3:136676496 T/C cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs17712049 0.908 rs62447149 chr7:48198747 C/G cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs4819052 0.851 rs2838833 chr21:46665160 C/T cg06618935 chr21:46677482 NA -0.37 -5.66 -0.45 9.9e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3008870 1.000 rs2985794 chr1:67425311 T/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs11785693 0.862 rs7007542 chr8:4996718 G/A cg26367366 chr8:4980734 NA 0.58 4.45 0.37 1.91e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs3733585 0.762 rs6449217 chr4:10009151 T/A cg11266682 chr4:10021025 SLC2A9 0.67 8.49 0.61 5.35e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7017914 0.934 rs13255886 chr8:71565954 G/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.5 -4.68 -0.39 7.37e-6 Bone mineral density; TGCT cis rs3751972 0.866 rs9646434 chr17:26251158 C/G cg02948944 chr17:26242737 NA 0.5 6.96 0.53 1.78e-10 Fractional exhaled nitric oxide (childhood); TGCT trans rs1973993 0.691 rs1980684 chr1:96890636 A/G cg10631902 chr5:14652156 NA 0.4 10.92 0.7 7.4e-20 Weight; TGCT trans rs629535 0.773 rs630235 chr8:70033529 T/G cg21567404 chr3:27674614 NA 0.58 9.28 0.64 7e-16 Dupuytren's disease; TGCT cis rs6988636 0.710 rs62521797 chr8:124134321 A/T cg22384356 chr8:124195192 FAM83A -0.5 -4.79 -0.39 4.71e-6 Urinary uromodulin levels; TGCT cis rs7809950 0.953 rs2520267 chr7:107187497 T/C cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs11690935 0.549 rs796839 chr2:172916214 A/C cg13550731 chr2:172543902 DYNC1I2 0.69 6.39 0.5 3.06e-9 Schizophrenia; TGCT cis rs797680 0.964 rs1060622 chr1:93620393 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.13 -0.42 1.09e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs910316 1.000 rs7142235 chr14:75559963 T/C cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs2010099 0.759 rs116358073 chr3:124299095 G/A cg17170942 chr3:124452405 UMPS -0.4 -4.59 -0.38 1.07e-5 Thyroid peroxidase antibody levels; TGCT cis rs12579753 0.810 rs10862355 chr12:82162698 C/T cg07988820 chr12:82153109 PPFIA2 -0.61 -6.82 -0.52 3.63e-10 Resting heart rate; TGCT cis rs453301 0.719 rs34004903 chr8:8892604 C/T cg06636001 chr8:8085503 FLJ10661 -0.66 -5.58 -0.45 1.42e-7 Joint mobility (Beighton score); TGCT cis rs4975709 0.610 rs1531994 chr5:1859297 T/C cg14773178 chr5:1868261 NA 0.34 5.62 0.45 1.21e-7 Cardiovascular disease risk factors; TGCT cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg17178900 chr1:205818956 PM20D1 0.7 9.77 0.66 4.54e-17 Menarche (age at onset); TGCT cis rs854765 0.547 rs2955385 chr17:17939247 C/T cg04398451 chr17:18023971 MYO15A -0.32 -5.12 -0.42 1.11e-6 Total body bone mineral density; TGCT cis rs9325144 0.647 rs11169258 chr12:39113040 C/T cg10518543 chr12:38710700 ALG10B -0.5 -4.69 -0.39 6.99e-6 Morning vs. evening chronotype; TGCT cis rs11690935 0.851 rs6731562 chr2:172798262 T/C cg13550731 chr2:172543902 DYNC1I2 -0.81 -7.08 -0.54 9.26e-11 Schizophrenia; TGCT cis rs9902453 0.769 rs7210288 chr17:28243473 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.28 0.55 3.32e-11 Coffee consumption (cups per day); TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg07157834 chr1:205819609 PM20D1 0.48 8.44 0.6 6.93e-14 Menarche (age at onset); TGCT cis rs1723838 0.826 rs1531001 chr11:73606963 G/A cg18195628 chr11:73498948 MRPL48 0.92 4.5 0.38 1.51e-5 Obesity-related traits; TGCT cis rs72945132 0.579 rs61341131 chr11:70246956 C/A cg00319359 chr11:70116639 PPFIA1 0.9 6.82 0.52 3.52e-10 Coronary artery disease; TGCT cis rs9905704 0.647 rs6503888 chr17:57028126 T/C cg12560992 chr17:57184187 TRIM37 0.58 5.05 0.41 1.52e-6 Testicular germ cell tumor; TGCT cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.07 12.04 0.73 1.36e-22 Height; TGCT cis rs10771431 0.817 rs17202253 chr12:9361850 A/G cg08997352 chr12:9597637 DDX12 -0.26 -5.24 -0.43 6.71e-7 Breast size; TGCT cis rs9811216 1.000 rs12696304 chr3:169481271 C/G cg08193579 chr3:169529701 LRRC34 0.28 4.6 0.38 1.03e-5 Neutrophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs4938534 0.750 rs1944927 chr11:111287404 C/A cg24049888 chr11:111250129 POU2AF1 -0.26 -4.54 -0.38 1.3e-5 Primary biliary cholangitis; TGCT cis rs4711350 0.723 rs608971 chr6:33702079 C/T cg00334056 chr6:33755658 LEMD2 0.33 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs9467711 1.000 rs9467707 chr6:26327905 G/C cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs539096 0.607 rs3001723 chr1:44037685 G/A cg12908607 chr1:44402522 ARTN 0.4 4.43 0.37 2.02e-5 Intelligence (multi-trait analysis); TGCT cis rs13216391 0.628 rs55865034 chr6:7776136 T/A cg16988958 chr6:7987739 MGC26597 0.26 4.52 0.38 1.4e-5 Hip circumference adjusted for BMI; TGCT cis rs10992471 0.651 rs2296669 chr9:95373790 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.58 5.2 0.42 8.05e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT trans rs2727020 0.553 rs3907576 chr11:49536639 A/C cg03929089 chr4:120376271 NA -0.66 -7.62 -0.56 5.75e-12 Coronary artery disease; TGCT cis rs2235642 0.928 rs1057610 chr16:1605537 T/C cg10465839 chr16:1584050 IFT140;TMEM204 -0.29 -4.83 -0.4 3.88e-6 Coronary artery disease; TGCT cis rs3008870 1.000 rs6673462 chr1:67461857 A/C cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs6089584 0.586 rs4925216 chr20:60599923 G/A cg06108461 chr20:60628389 TAF4 -0.43 -5.24 -0.43 6.68e-7 Body mass index; TGCT cis rs739401 0.572 rs739399 chr11:3016452 A/G cg05729581 chr11:3078854 CARS -0.59 -5.39 -0.44 3.47e-7 Longevity; TGCT cis rs7552404 0.731 rs5745458 chr1:76345429 G/A cg10523679 chr1:76189770 ACADM -0.83 -7.8 -0.57 2.24e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11758351 0.660 rs2143345 chr6:26229148 C/T cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.6 -4.54 -0.38 1.32e-5 Gout;Renal underexcretion gout; TGCT cis rs875971 1.000 rs778722 chr7:65844828 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs12580194 1.000 rs7971451 chr12:55699950 G/A cg20672549 chr12:56432144 IKZF4 0.26 4.71 0.39 6.51e-6 Cancer; TGCT cis rs3110496 0.819 rs3115097 chr17:27907313 A/G cg05877788 chr17:27899874 TP53I13 -0.52 -4.75 -0.39 5.47e-6 Height; TGCT cis rs7267979 0.966 rs2227892 chr20:25264814 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2046867 0.862 rs75638790 chr3:72830502 C/T cg25664220 chr3:72788482 NA -0.58 -7.21 -0.54 4.9e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2228479 0.850 rs62054224 chr16:89892071 C/T cg06558623 chr16:89946397 TCF25 0.55 4.79 0.4 4.69e-6 Skin colour saturation; TGCT cis rs9796 0.727 rs61203391 chr15:41352912 C/G cg18705301 chr15:41695430 NDUFAF1 -0.49 -6.18 -0.49 8.53e-9 Menopause (age at onset); TGCT cis rs7714584 1.000 rs76548544 chr5:150223515 T/A cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs3748682 0.861 rs2291297 chr1:38272660 G/A cg04496824 chr1:38276835 MTF1 0.21 4.61 0.38 1.01e-5 Hypothyroidism; TGCT cis rs10875746 0.579 rs10875778 chr12:48624655 T/C cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs13102973 0.965 rs4280794 chr4:135857174 T/C cg14419869 chr4:135874104 NA 0.23 4.58 0.38 1.12e-5 Subjective well-being; TGCT cis rs42648 0.869 rs6970376 chr7:89938086 A/G cg25739043 chr7:89950458 NA 0.71 7.16 0.54 6.18e-11 Homocysteine levels; TGCT cis rs796364 0.951 rs769952 chr2:200734368 C/T cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs3960554 0.808 rs13438599 chr7:75768022 G/A cg17325771 chr7:75508891 RHBDD2 -0.52 -4.44 -0.37 2e-5 Eotaxin levels; TGCT cis rs7226408 0.901 rs17568091 chr18:34739590 T/C cg06757138 chr18:34340585 FHOD3 0.26 4.92 0.4 2.69e-6 Obesity-related traits; TGCT cis rs9372498 0.536 rs2356501 chr6:118942371 C/A cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs12580194 0.957 rs73118932 chr12:55706631 C/T cg20672549 chr12:56432144 IKZF4 0.28 4.55 0.38 1.26e-5 Cancer; TGCT cis rs12971120 0.783 rs7229256 chr18:72169129 T/A cg26446133 chr18:72167187 CNDP2 -0.4 -7.77 -0.57 2.58e-12 Refractive error; TGCT trans rs11722228 1.000 rs11722228 chr4:9915741 C/T cg26043149 chr18:55253948 FECH 0.75 7.76 0.57 2.64e-12 Gout;Urate levels;Serum uric acid levels; TGCT cis rs9926296 0.605 rs12709094 chr16:89853017 A/G cg03388025 chr16:89894329 SPIRE2 0.5 8.7 0.62 1.73e-14 Vitiligo; TGCT cis rs595982 0.559 rs73061632 chr19:49361663 G/A cg21252483 chr19:49399788 TULP2 -0.42 -6.46 -0.5 2.11e-9 Red cell distribution width; TGCT cis rs12477438 0.765 rs2309520 chr2:99570477 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.57 4.91 0.4 2.84e-6 Chronic sinus infection; TGCT trans rs1974653 0.672 rs7288396 chr22:20086571 G/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs1998418 0.673 rs11245391 chr10:126547439 A/G cg03585084 chr10:126284563 LHPP 0.33 4.88 0.4 3.22e-6 Mean platelet volume; TGCT cis rs7772486 0.754 rs9373475 chr6:146126419 C/T cg05347473 chr6:146136440 FBXO30 0.54 5.09 0.42 1.28e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7584330 0.826 rs72620824 chr2:238381083 G/A cg14458575 chr2:238380390 NA 0.6 9.37 0.64 4.27e-16 Prostate cancer; TGCT cis rs597539 0.652 rs622082 chr11:68703959 A/G cg06112835 chr11:68658793 MRPL21 0.48 8.14 0.59 3.49e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs858239 0.600 rs7456915 chr7:23143049 T/C cg05602783 chr7:23145260 KLHL7 -0.68 -5.75 -0.46 6.69e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs2172802 0.693 rs11131337 chr4:62491495 T/C cg04118610 chr4:62707027 LPHN3 -0.43 -4.6 -0.38 1.02e-5 Partial epilepsies; TGCT cis rs7432375 0.901 rs4521165 chr3:136369710 T/C cg12473912 chr3:136751656 NA -0.36 -5.06 -0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs1385374 0.858 rs12321643 chr12:129302867 A/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs524023 1.000 rs3825018 chr11:64358809 G/A cg07733098 chr11:64478343 NRXN2 0.31 4.66 0.39 7.9e-6 Urate levels in obese individuals; TGCT cis rs9788721 0.836 rs17483686 chr15:78733390 A/T cg18825076 chr15:78729989 IREB2 -0.33 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs2120019 1.000 rs7162900 chr15:75368017 T/C cg11632617 chr15:75315747 PPCDC -0.34 -4.82 -0.4 4.18e-6 Blood trace element (Zn levels); TGCT cis rs362272 0.524 rs13150241 chr4:3367281 A/G cg22655196 chr4:3374909 RGS12 0.22 4.45 0.37 1.86e-5 Serum sulfate level; TGCT cis rs9419702 0.639 rs4367873 chr10:133533485 C/T cg23460707 chr10:133558971 NA 0.42 4.63 0.38 9.08e-6 Survival in rectal cancer; TGCT cis rs73198271 0.740 rs10098636 chr8:8647324 C/T cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs910316 0.935 rs175076 chr14:75505486 A/G cg23033748 chr14:75592666 NEK9 -0.27 -4.65 -0.39 8.3e-6 Height; TGCT cis rs1008375 0.618 rs6842764 chr4:17568420 C/T cg16339924 chr4:17578868 LAP3 -0.77 -6.37 -0.5 3.33e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12682352 0.652 rs3827806 chr8:8724276 C/T cg15556689 chr8:8085844 FLJ10661 0.66 6.06 0.48 1.52e-8 Neuroticism; TGCT cis rs4919694 1.000 rs77969925 chr10:104649357 C/T cg04362960 chr10:104952993 NT5C2 1.03 6.95 0.53 1.83e-10 Arsenic metabolism; TGCT cis rs2806561 0.704 rs2746560 chr1:23526279 G/A cg12483005 chr1:23474871 LUZP1 0.42 5.41 0.44 3.15e-7 Height; TGCT cis rs6598955 0.671 rs17163746 chr1:26564230 C/A cg04990556 chr1:26633338 UBXN11 0.64 5.11 0.42 1.19e-6 Obesity-related traits; TGCT cis rs7582180 0.614 rs4851309 chr2:100975390 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.79 0.4 4.66e-6 Intelligence (multi-trait analysis); TGCT cis rs617219 0.698 rs10055956 chr5:78479678 G/A cg09550809 chr5:78407562 BHMT 0.4 5.75 0.46 6.44e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7246657 0.823 rs4802236 chr19:37919246 A/G cg18154014 chr19:37997991 ZNF793 0.95 6.55 0.51 1.4e-9 Coronary artery calcification; TGCT cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.88 -5.91 -0.47 3.15e-8 Alzheimer's disease; TGCT cis rs8141529 0.871 rs5762877 chr22:29277555 G/A cg02153584 chr22:29168773 CCDC117 0.7 5.16 0.42 9.38e-7 Lymphocyte counts; TGCT cis rs1061377 1.000 rs3733274 chr4:39122577 A/G cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs9302001 0.883 rs7329015 chr13:95453928 C/T cg07483244 chr13:95358924 NA 0.37 4.62 0.38 9.47e-6 Panic disorder; TGCT cis rs4727027 0.933 rs7788925 chr7:148831621 A/G cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9814567 1.000 rs7611828 chr3:134250325 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs950169 0.580 rs35516100 chr15:85195430 C/T cg11189052 chr15:85197271 WDR73 0.76 6.33 0.49 4.04e-9 Schizophrenia; TGCT cis rs4443656 0.711 rs67760158 chr8:21548344 C/T cg26401870 chr8:21882439 NPM2 -0.47 -4.61 -0.38 9.76e-6 Blood protein levels; TGCT cis rs9646954 0.560 rs4149507 chr2:101032745 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.67 0.39 7.79e-6 Intelligence (multi-trait analysis); TGCT cis rs11673344 0.504 rs2385375 chr19:37578522 G/C cg08039142 chr19:36980659 ZNF566 0.5 4.6 0.38 1.02e-5 Obesity-related traits; TGCT cis rs6121246 0.529 rs6058152 chr20:30178107 G/A cg21427119 chr20:30132790 HM13 -0.43 -6.28 -0.49 5.3e-9 Mean corpuscular hemoglobin; TGCT cis rs9611565 0.546 rs34077262 chr22:42061639 A/G cg06634786 chr22:41940651 POLR3H 0.83 7.91 0.58 1.22e-12 Vitiligo; TGCT cis rs3213545 0.700 rs10849829 chr12:121470256 A/G cg02403541 chr12:121454288 C12orf43 -0.7 -8.03 -0.58 6.44e-13 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs698813 0.555 rs7605771 chr2:44479778 G/A cg00619915 chr2:44497795 NA -0.24 -5.62 -0.45 1.19e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs999943 0.846 rs10947422 chr6:33611351 G/A cg14003231 chr6:33640908 ITPR3 0.39 4.9 0.4 2.97e-6 Obesity (extreme); TGCT cis rs9677476 0.516 rs1549339 chr2:231982826 G/A cg27665808 chr2:232055229 NA 0.37 4.59 0.38 1.05e-5 Food antigen IgG levels; TGCT cis rs45430 1.000 rs443099 chr21:42743327 G/T cg22778903 chr21:42741698 MX2 0.33 5.38 0.43 3.63e-7 Melanoma; TGCT cis rs8141529 0.778 rs7287806 chr22:29213011 G/A cg02153584 chr22:29168773 CCDC117 0.68 5.9 0.47 3.31e-8 Lymphocyte counts; TGCT cis rs8177253 0.965 rs1525889 chr3:133490033 A/C cg16414030 chr3:133502952 NA -0.61 -9.84 -0.66 3.15e-17 Iron status biomarkers; TGCT cis rs8072100 0.676 rs9908049 chr17:45502096 G/C cg08085267 chr17:45401833 C17orf57 -0.51 -5.64 -0.45 1.11e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7542091 0.704 rs7550330 chr1:210044587 G/A cg00989853 chr1:209979345 IRF6 0.43 4.58 0.38 1.12e-5 Monobrow; TGCT cis rs2204008 0.837 rs11168334 chr12:37961768 A/G cg26384229 chr12:38710491 ALG10B 0.81 7.19 0.54 5.25e-11 Bladder cancer; TGCT cis rs2243480 1.000 rs67536397 chr7:65947917 G/A cg18252515 chr7:66147081 NA -1.18 -7.56 -0.56 7.99e-12 Diabetic kidney disease; TGCT cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg04267008 chr7:1944627 MAD1L1 -0.4 -5.37 -0.43 3.81e-7 Bipolar disorder and schizophrenia; TGCT cis rs1008375 0.966 rs4235389 chr4:17696280 A/G cg18681998 chr4:17616180 MED28 0.76 7.55 0.56 8.3e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11098499 0.780 rs7680914 chr4:120563053 A/G cg09307838 chr4:120376055 NA 0.7 6.52 0.51 1.6e-9 Corneal astigmatism; TGCT cis rs6088580 0.634 rs1205338 chr20:32925625 C/G cg08999081 chr20:33150536 PIGU -0.25 -4.85 -0.4 3.66e-6 Glomerular filtration rate (creatinine); TGCT cis rs4776059 0.798 rs7167494 chr15:52928453 C/G cg25063058 chr15:52860530 ARPP19 -0.58 -4.49 -0.37 1.61e-5 Schizophrenia; TGCT cis rs79349575 0.783 rs12453394 chr17:46994970 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs514406 0.861 rs503015 chr1:53254456 T/C cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs2836974 0.897 rs2836944 chr21:40593539 G/A cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.67e-16 Cognitive function; TGCT cis rs4285028 0.731 rs2332035 chr3:121715432 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.68 -5.65 -0.45 1.03e-7 Multiple sclerosis; TGCT cis rs2836974 0.931 rs12151994 chr21:40690397 A/C cg11644478 chr21:40555479 PSMG1 0.97 9.14 0.63 1.54e-15 Cognitive function; TGCT cis rs514406 0.570 rs1332776 chr1:53189816 C/T cg22166914 chr1:53195759 ZYG11B 0.45 8.41 0.6 8.07e-14 Monocyte count; TGCT cis rs9929218 0.861 rs3114409 chr16:68732049 A/C cg01251360 chr16:68772225 CDH1 0.29 4.76 0.39 5.36e-6 Colorectal cancer; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg07167872 chr1:205819463 PM20D1 0.59 7.65 0.57 4.74e-12 Menarche (age at onset); TGCT cis rs854765 0.547 rs2955370 chr17:17966945 C/T cg09796270 chr17:17721594 SREBF1 -0.24 -4.69 -0.39 7e-6 Total body bone mineral density; TGCT cis rs651907 0.514 rs11706494 chr3:101509475 A/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT trans rs17471911 0.708 rs7919734 chr10:100771294 C/T cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs2338224 1.000 rs12517661 chr5:71745716 C/T cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs7107174 1.000 rs58565853 chr11:78036707 C/T cg12700464 chr11:78128424 GAB2 -0.66 -4.71 -0.39 6.53e-6 Testicular germ cell tumor; TGCT cis rs2242116 1.000 rs2242116 chr3:46941116 A/G cg27129171 chr3:47204927 SETD2 0.64 6.28 0.49 5.31e-9 Birth weight; TGCT cis rs7809950 1.000 rs986994 chr7:107104115 G/T cg23024343 chr7:107201750 COG5 -0.34 -5.26 -0.43 6.05e-7 Coronary artery disease; TGCT cis rs2153535 0.580 rs1328862 chr6:8526681 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs6089584 0.830 rs4925331 chr20:60580174 T/C cg06108461 chr20:60628389 TAF4 -0.58 -8.35 -0.6 1.12e-13 Body mass index; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg20007245 chr22:24372913 LOC391322 0.7 6.91 0.53 2.2e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12815613 0.621 rs11065360 chr12:121386532 A/G cg02403541 chr12:121454288 C12orf43 -0.55 -5.07 -0.41 1.41e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs4665809 0.590 rs1469523 chr2:26474631 T/A cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs7072216 0.763 rs6584202 chr10:100170383 G/A cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs514406 0.825 rs497535 chr1:53284677 A/G cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs7666738 0.830 rs28456179 chr4:98991439 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs13126513 0.519 rs959247 chr4:100556984 A/G cg05468953 chr4:100565104 NA 0.4 5.31 0.43 4.95e-7 Metabolite levels (MHPG); TGCT cis rs12497850 0.931 rs4974085 chr3:48924900 C/T cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs11098499 0.697 rs28458294 chr4:120238924 T/C cg09307838 chr4:120376055 NA 0.63 6.22 0.49 7.01e-9 Corneal astigmatism; TGCT cis rs2840044 1.000 rs11080357 chr17:33898933 G/A cg05299278 chr17:33885742 SLFN14 -0.23 -5.32 -0.43 4.65e-7 Response to radiotherapy in cancer (late toxicity); TGCT cis rs832540 0.564 rs33329 chr5:56145068 T/C cg12311346 chr5:56204834 C5orf35 -0.49 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs6570726 0.846 rs4896824 chr6:145927048 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.5 -0.37 1.53e-5 Lobe attachment (rater-scored or self-reported); TGCT trans rs1814175 0.817 rs11040474 chr11:49708441 G/A cg11707556 chr5:10655725 ANKRD33B -0.38 -7.6 -0.56 6.14e-12 Height; TGCT cis rs644799 0.542 rs10831416 chr11:95467220 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.6 5.83 0.46 4.5e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6671200 1.000 rs6678964 chr1:95694268 C/T cg20701556 chr1:95698924 RWDD3 0.67 6.03 0.48 1.75e-8 Stearic acid (18:0) levels; TGCT cis rs6728642 1.000 rs11900461 chr2:97615993 C/T cg26665480 chr2:98280029 ACTR1B -0.98 -5.36 -0.43 3.94e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs55704346 0.935 rs12510672 chr4:25192577 C/T cg26487582 chr4:25322200 ZCCHC4 0.18 4.44 0.37 1.97e-5 Tonsillectomy; TGCT cis rs713587 0.967 rs713586 chr2:25158008 A/G cg01884057 chr2:25150051 NA 0.39 8.05 0.59 5.72e-13 Body mass index in non-asthmatics; TGCT cis rs6690583 0.623 rs11588160 chr1:85444226 T/G cg20280350 chr1:85513789 MCOLN3 -0.67 -4.5 -0.37 1.52e-5 Serum sulfate level; TGCT cis rs60154123 0.730 rs4844987 chr1:210458190 G/T cg22029157 chr1:209979665 IRF6 0.6 4.46 0.37 1.81e-5 Coronary artery disease; TGCT cis rs7760949 0.852 rs9475800 chr6:13932230 A/G cg27413430 chr6:13925136 RNF182 0.74 6.83 0.52 3.37e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs11718455 0.961 rs3846068 chr3:44029835 G/A cg08738300 chr3:44038990 NA 0.81 6.0 0.47 2.02e-8 Coronary artery disease; TGCT cis rs12579753 0.871 rs35801863 chr12:82238818 A/T cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs644799 1.000 rs494829 chr11:95571750 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.11 0.59 4.26e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2288073 0.619 rs6713263 chr2:24375463 A/G cg06627628 chr2:24431161 ITSN2 -0.16 -4.45 -0.37 1.93e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs7100689 0.646 rs2050824 chr10:82123563 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs7104764 0.957 rs58692051 chr11:207410 C/T cg18336825 chr11:236787 PSMD13;SIRT3 -0.99 -10.18 -0.67 4.61e-18 Menarche (age at onset); TGCT cis rs904251 0.861 rs1757180 chr6:37486145 T/C cg01843034 chr6:37503916 NA -0.51 -6.22 -0.49 7.05e-9 Cognitive performance; TGCT cis rs72700829 0.507 rs11204766 chr1:151018060 G/C cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Schizophrenia; TGCT cis rs11679640 0.610 rs56383943 chr2:43113641 G/A cg00484711 chr2:42331922 NA -0.2 -4.63 -0.38 9.27e-6 White matter hyperintensity burden; TGCT cis rs8028182 0.583 rs9944207 chr15:75912889 A/T cg20655648 chr15:75932815 IMP3 0.63 4.83 0.4 3.87e-6 Sudden cardiac arrest; TGCT cis rs35883536 0.647 rs12023028 chr1:101042717 C/T cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.1e-12 Monocyte count; TGCT cis rs651907 0.535 rs13085776 chr3:101505507 A/G cg11279151 chr3:101281821 RG9MTD1 -0.29 -6.41 -0.5 2.73e-9 Colorectal cancer; TGCT cis rs12210905 1.000 rs72843609 chr6:27125877 G/A cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.49 -0.5 1.85e-9 Alzheimer's disease; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg24503407 chr1:205819492 PM20D1 0.59 8.22 0.59 2.3e-13 Menarche (age at onset); TGCT cis rs2836974 0.865 rs7282624 chr21:40667040 C/T cg17971929 chr21:40555470 PSMG1 0.97 9.4 0.65 3.57e-16 Cognitive function; TGCT cis rs10791111 1 rs10791111 chr11:130856099 T/G cg12179176 chr11:130786555 SNX19 0.6 5.75 0.46 6.67e-8 Autism spectrum disorder or schizophrenia; TGCT trans rs1268083 0.546 rs9398785 chr6:126057748 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.74 -7.15 -0.54 6.58e-11 Migraine; TGCT cis rs11864453 0.713 rs12708927 chr16:72126165 C/T cg14768367 chr16:72042858 DHODH 0.5 4.8 0.4 4.5e-6 Fibrinogen levels; TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs2456568 0.802 rs7115629 chr11:93635477 G/A cg14065697 chr11:93583672 C11orf90 -0.37 -4.63 -0.38 9.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6940638 0.531 rs12211984 chr6:26986054 G/C cg15659132 chr6:26577336 NA 0.55 5.55 0.45 1.62e-7 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.805 rs12146846 chr12:37985847 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs2549003 1.000 rs9282761 chr5:131822224 T/C cg00255919 chr5:131827918 IRF1 0.2 4.65 0.39 8.22e-6 Asthma (sex interaction); TGCT cis rs597539 0.652 rs613128 chr11:68638058 G/T cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10206020 0.885 rs11899557 chr2:1576123 G/T cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs12762955 0.519 rs7094331 chr10:1022816 T/C cg18964960 chr10:1102726 WDR37 -0.59 -5.24 -0.43 6.73e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg03264133 chr6:25882463 NA -0.65 -6.06 -0.48 1.5e-8 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.44 0.56 1.45e-11 Platelet count; TGCT cis rs2836974 0.897 rs2836927 chr21:40543216 T/C cg06238570 chr21:40685208 BRWD1 0.73 6.66 0.51 8.12e-10 Cognitive function; TGCT cis rs9921222 1.000 rs10794639 chr16:377367 A/G cg08923669 chr16:420230 MRPL28 -0.48 -5.07 -0.41 1.43e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs10465746 0.657 rs67045520 chr1:84414998 G/T cg10977910 chr1:84465055 TTLL7 0.67 6.74 0.52 5.32e-10 Obesity-related traits; TGCT cis rs9325144 0.541 rs7303395 chr12:38664124 C/T cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs9372498 0.831 rs62421532 chr6:118705454 A/T cg18833306 chr6:118973337 C6orf204 -0.61 -4.76 -0.39 5.22e-6 Diastolic blood pressure; TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs10423674 0.526 rs2023878 chr19:18834124 A/G cg20185461 chr19:18899082 COMP 0.52 5.02 0.41 1.78e-6 Menarche (age at onset); TGCT cis rs7714584 1.000 rs74955473 chr5:150174558 T/A cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg22166914 chr1:53195759 ZYG11B 0.36 5.96 0.47 2.45e-8 Monocyte count; TGCT cis rs736408 0.812 rs2239699 chr3:52827915 C/T cg10802521 chr3:52805072 NEK4 -0.63 -7.07 -0.54 9.9e-11 Bipolar disorder; TGCT cis rs9534288 0.664 rs1926447 chr13:46629944 C/T cg15192986 chr13:46630673 CPB2 0.57 7.26 0.55 3.65e-11 Blood protein levels; TGCT cis rs2797160 1.000 rs2747723 chr6:126010790 C/T cg05901451 chr6:126070800 HEY2 0.73 6.3 0.49 4.83e-9 Endometrial cancer; TGCT cis rs17345786 0.906 rs59359251 chr3:101146362 A/C cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs8014204 0.836 rs12588415 chr14:75278211 G/A cg06637938 chr14:75390232 RPS6KL1 0.68 6.49 0.5 1.84e-9 Caffeine consumption; TGCT cis rs7020830 0.894 rs13300951 chr9:37146627 A/G cg14294708 chr9:37120828 ZCCHC7 1.31 20.34 0.88 2.57e-41 Schizophrenia; TGCT cis rs1580019 0.885 rs4460270 chr7:32496450 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs854765 0.565 rs4072738 chr17:17884547 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.26 0.55 3.67e-11 Total body bone mineral density; TGCT cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg27211696 chr2:191398769 TMEM194B 0.29 5.3 0.43 5.19e-7 Pulse pressure; TGCT cis rs477895 1.000 rs2276014 chr11:64081445 G/A cg23719950 chr11:63933701 MACROD1 -0.59 -4.6 -0.38 1.01e-5 Mean platelet volume; TGCT cis rs8016982 0.632 rs7142641 chr14:81677454 A/G cg01989461 chr14:81687754 GTF2A1 0.62 4.62 0.38 9.48e-6 Schizophrenia; TGCT cis rs6558530 0.730 rs7341635 chr8:1721643 G/A cg09410841 chr8:1729607 CLN8 0.83 9.76 0.66 4.92e-17 Systolic blood pressure; TGCT cis rs4665809 1.000 rs13030858 chr2:26315451 G/A cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs6921919 0.583 rs9461456 chr6:28343816 A/G cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7635838 0.718 rs2594981 chr3:11380638 C/G cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs9814567 1.000 rs11919350 chr3:134235970 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2467099 0.504 rs55956362 chr17:73901294 G/T cg02678768 chr17:74002944 EVPL 0.27 4.44 0.37 1.97e-5 Systolic blood pressure; TGCT cis rs35306767 0.761 rs11253558 chr10:1043983 T/C cg18964960 chr10:1102726 WDR37 0.78 5.46 0.44 2.45e-7 Eosinophil percentage of granulocytes; TGCT cis rs9549367 0.601 rs558869 chr13:113849932 G/T cg18105134 chr13:113819100 PROZ 0.46 8.58 0.61 3.25e-14 Platelet distribution width; TGCT cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg13695892 chr22:41940480 POLR3H -0.83 -7.48 -0.56 1.18e-11 Vitiligo; TGCT cis rs11112613 0.762 rs17037308 chr12:105949847 T/G cg03607813 chr12:105948248 NA 0.52 6.0 0.47 2.03e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs4566357 0.576 rs6750845 chr2:227911037 T/G cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.92e-7 Coronary artery disease; TGCT cis rs35000415 0.688 rs13232316 chr7:128715299 A/T cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs288326 0.561 rs77426227 chr2:183890678 A/T cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs9733 0.596 rs6669369 chr1:150695892 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs62064224 0.703 rs62065492 chr17:30822607 C/T cg18200150 chr17:30822561 MYO1D 0.57 8.04 0.59 6.08e-13 Schizophrenia; TGCT cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg25151919 chr3:44754333 ZNF502 -0.39 -4.55 -0.38 1.26e-5 Depressive symptoms; TGCT cis rs1862618 0.613 rs252889 chr5:56227069 C/A cg12311346 chr5:56204834 C5orf35 -0.57 -6.13 -0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs6121246 0.559 rs1062794 chr20:30381758 G/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs7586879 0.752 rs11683748 chr2:25130434 C/T cg01884057 chr2:25150051 NA 0.26 4.67 0.39 7.75e-6 Body mass index; TGCT cis rs9611519 0.780 rs2235852 chr22:41661154 G/T cg03806693 chr22:41940476 POLR3H -0.76 -5.23 -0.42 7.06e-7 Neuroticism; TGCT cis rs4819052 0.851 rs4819046 chr21:46664955 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.81 0.52 3.67e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1403694 0.695 rs5029970 chr3:186434491 T/C cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs4478858 0.663 rs11591060 chr1:31780012 G/A cg07478791 chr1:31886160 SERINC2 -0.48 -4.61 -0.38 1e-5 Alcohol dependence; TGCT cis rs875971 0.862 rs6959268 chr7:65812966 G/A cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.43e-7 Aortic root size; TGCT cis rs2594989 0.943 rs346068 chr3:11302933 A/G cg00170343 chr3:11313890 ATG7 0.69 4.97 0.41 2.21e-6 Circulating chemerin levels; TGCT cis rs9682041 1.000 rs6444920 chr3:170090374 A/G cg07589077 chr3:170072950 NA 0.31 4.7 0.39 6.94e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs2486288 0.656 rs2413773 chr15:45549442 C/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs651907 0.514 rs34301719 chr3:101417993 C/T cg11279151 chr3:101281821 RG9MTD1 -0.32 -6.26 -0.49 5.65e-9 Colorectal cancer; TGCT cis rs2235642 0.826 rs8053605 chr16:1594158 G/A cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.35 -0.43 4.1e-7 Coronary artery disease; TGCT cis rs832540 0.931 rs331499 chr5:56210923 C/T cg12311346 chr5:56204834 C5orf35 -0.46 -4.79 -0.4 4.58e-6 Coronary artery disease; TGCT cis rs3617 0.625 rs6445541 chr3:52880128 G/T cg10802521 chr3:52805072 NEK4 -0.59 -6.82 -0.52 3.64e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6500602 0.702 rs4786493 chr16:4500122 C/T cg08645402 chr16:4508243 NA 0.17 4.65 0.39 8.38e-6 Schizophrenia; TGCT cis rs9467711 0.606 rs9348709 chr6:26360311 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6570726 0.875 rs373313 chr6:145857791 T/C cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9902453 0.740 rs2617884 chr17:28120430 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs17712049 0.908 rs58887783 chr7:48198403 C/T cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs1062177 1.000 rs17741826 chr5:151149262 C/T cg12924095 chr5:151150029 G3BP1 -0.35 -5.04 -0.41 1.6e-6 Preschool internalizing problems; TGCT cis rs9916302 0.851 rs11868029 chr17:37650304 A/G cg15445000 chr17:37608096 MED1 0.33 4.93 0.4 2.59e-6 Glomerular filtration rate (creatinine); TGCT cis rs9457247 0.508 rs9457268 chr6:167503639 A/T cg07741184 chr6:167504864 NA 0.27 5.25 0.43 6.4e-7 Crohn's disease; TGCT cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.4 -4.76 -0.39 5.24e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs13256369 1.000 rs12545771 chr8:8567977 C/G cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs1635 0.655 rs73742539 chr6:28305471 C/T cg15743358 chr6:28303923 ZNF323 -1.29 -6.5 -0.5 1.73e-9 Schizophrenia; TGCT cis rs2115630 1.000 rs6496441 chr15:85363348 A/G cg17173187 chr15:85201210 NMB -0.4 -4.89 -0.4 3.1e-6 P wave terminal force; TGCT cis rs727479 0.543 rs1143704 chr15:51510702 T/A cg19946085 chr15:51559439 CYP19A1 -0.3 -4.49 -0.37 1.62e-5 Estradiol levels; TGCT cis rs910316 1.000 rs28626045 chr14:75589195 G/C cg23033748 chr14:75592666 NEK9 0.27 4.71 0.39 6.59e-6 Height; TGCT cis rs617219 0.671 rs13165414 chr5:78548873 C/T cg23987322 chr5:78407566 BHMT 0.35 4.69 0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs13118159 0.872 rs4974605 chr4:1346389 C/G cg13395646 chr4:1353034 KIAA1530 -0.4 -4.87 -0.4 3.27e-6 Longevity; TGCT cis rs12477438 0.520 rs6542866 chr2:99764592 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg10802521 chr3:52805072 NEK4 -0.7 -8.75 -0.62 1.28e-14 Bipolar disorder; TGCT trans rs6089829 0.855 rs6090205 chr20:61665269 A/G cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs4460629 0.710 rs11264318 chr1:155083717 A/T cg23973274 chr1:155060172 NA -0.25 -4.5 -0.37 1.54e-5 Serum magnesium levels; TGCT trans rs916888 0.647 rs199449 chr17:44808902 G/A cg22968622 chr17:43663579 NA 1.05 10.19 0.68 4.43e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs308403 0.509 rs7690133 chr4:123673809 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.9 0.73 2.98e-22 Blood protein levels; TGCT trans rs3774749 0.565 rs6800021 chr3:50190346 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.7 6.81 0.52 3.67e-10 Intelligence (multi-trait analysis); TGCT cis rs7647973 1.000 rs13088309 chr3:49368317 A/G cg05785598 chr3:49045655 WDR6 0.39 4.62 0.38 9.58e-6 Menarche (age at onset); TGCT cis rs11190604 1.000 rs11190570 chr10:102227702 G/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1218582 0.741 rs11264283 chr1:154869552 A/G cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.48e-24 Prostate cancer; TGCT trans rs1814175 0.669 rs12364577 chr11:49707361 A/C cg15704280 chr7:45808275 SEPT13 -0.6 -6.94 -0.53 1.92e-10 Height; TGCT cis rs7666738 0.830 rs13124904 chr4:98856973 T/C cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg21672276 chr3:44754072 ZNF502 -0.41 -4.66 -0.39 7.99e-6 Depressive symptoms; TGCT cis rs611744 0.647 rs7015240 chr8:109262204 G/A cg21045802 chr8:109455806 TTC35 0.69 6.92 0.53 2.12e-10 Dupuytren's disease; TGCT cis rs77861329 1.000 rs9816434 chr3:52197513 C/T cg08692210 chr3:52188851 WDR51A 0.93 4.79 0.4 4.61e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs2013441 1.000 rs34089239 chr17:20057959 G/T cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs2455799 0.613 rs2470547 chr3:15737610 T/C cg16303742 chr3:15540471 COLQ -0.26 -4.87 -0.4 3.26e-6 Mean platelet volume; TGCT cis rs12210905 0.688 rs12196452 chr6:27344415 A/T cg08851530 chr6:28072375 NA 1.25 5.39 0.44 3.38e-7 Hip circumference adjusted for BMI; TGCT cis rs67311347 1.000 rs17078916 chr3:40445438 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs921968 0.613 rs2556388 chr2:219541056 T/C cg02176678 chr2:219576539 TTLL4 -0.33 -4.45 -0.37 1.91e-5 Mean corpuscular hemoglobin concentration; TGCT trans rs916888 0.773 rs199445 chr17:44817408 C/T cg22968622 chr17:43663579 NA 1.3 11.87 0.73 3.46e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1800469 0.928 rs12462166 chr19:41857404 T/C cg09537434 chr19:41945824 ATP5SL -0.5 -4.64 -0.38 8.9e-6 Colorectal cancer; TGCT cis rs6460942 0.915 rs17541242 chr7:12459068 A/G cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg16145915 chr7:1198662 ZFAND2A -0.46 -5.47 -0.44 2.36e-7 Longevity;Endometriosis; TGCT cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg12667521 chr19:29218732 NA 0.53 5.64 0.45 1.07e-7 Methadone dose in opioid dependence; TGCT cis rs806215 1.000 rs806216 chr7:127237862 C/A cg25922125 chr7:127225783 GCC1 -0.61 -6.41 -0.5 2.76e-9 Type 2 diabetes; TGCT trans rs941408 1.000 rs1076448 chr19:2792343 G/A cg19676328 chr12:49525230 TUBA1B -0.77 -7.88 -0.58 1.43e-12 Total cholesterol levels; TGCT cis rs2066819 1.000 rs117683816 chr12:56638267 T/C cg26714650 chr12:56694279 CS -1.32 -6.2 -0.49 7.69e-9 Psoriasis vulgaris; TGCT cis rs5769765 0.819 rs9616379 chr22:50312035 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs6951245 1.000 rs79443843 chr7:1075245 G/A cg18402987 chr7:1209562 NA 0.69 5.63 0.45 1.13e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12048904 0.505 rs11166511 chr1:101240686 G/C cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.68 -5.36 -0.43 3.96e-7 Multiple sclerosis; TGCT cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9517313 0.897 rs4772087 chr13:99115041 A/G cg07423050 chr13:99094983 FARP1 0.31 6.94 0.53 1.95e-10 Neuroticism; TGCT cis rs2836974 0.899 rs2836957 chr21:40623134 T/C cg11890956 chr21:40555474 PSMG1 1.11 12.48 0.75 1.21e-23 Cognitive function; TGCT cis rs7044106 0.791 rs10984995 chr9:123479210 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.56 0.51 1.3e-9 Hip circumference adjusted for BMI; TGCT cis rs875971 0.862 rs1612452 chr7:65573896 T/A cg11764359 chr7:65958608 NA -0.53 -4.68 -0.39 7.26e-6 Aortic root size; TGCT cis rs67072384 0.892 rs72964172 chr11:72436436 G/A cg03713592 chr11:72463424 ARAP1 -0.94 -4.67 -0.39 7.65e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs2204008 0.665 rs11179830 chr12:38220966 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.45 0.56 1.35e-11 Bladder cancer; TGCT cis rs6433857 0.536 rs4625864 chr2:181353942 G/C cg23363182 chr2:181467187 NA -0.32 -4.83 -0.4 3.98e-6 Body mass index; TGCT cis rs3743266 0.507 rs10162677 chr15:60748568 C/T cg18480781 chr15:60294291 NA 0.63 5.01 0.41 1.81e-6 Menarche (age at onset); TGCT cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg22663859 chr13:21900854 NA 0.34 4.93 0.4 2.59e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs1997103 1.000 rs2009441 chr7:55405989 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6964587 0.692 rs2374550 chr7:91820987 A/G cg17063962 chr7:91808500 NA 0.77 7.17 0.54 6.08e-11 Breast cancer; TGCT cis rs9527 0.615 rs4919682 chr10:104584330 C/T cg04362960 chr10:104952993 NT5C2 0.57 4.65 0.39 8.47e-6 Arsenic metabolism; TGCT cis rs4727027 0.933 rs6961605 chr7:148870108 G/A cg23583168 chr7:148888333 NA -0.74 -9.61 -0.65 1.1e-16 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9914544 0.545 rs8071783 chr17:18807939 C/G cg26378065 chr17:18585709 ZNF286B 0.53 4.65 0.39 8.4e-6 Educational attainment (years of education); TGCT cis rs10782582 0.609 rs2029682 chr1:76341619 T/C cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs9467773 0.967 rs9358954 chr6:26531178 A/G cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs2932538 0.922 rs4838961 chr1:113163967 T/C cg22162597 chr1:113214053 CAPZA1 -0.27 -5.98 -0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs6539288 0.513 rs7977247 chr12:107259470 T/C cg15890332 chr12:107067104 RFX4 0.22 4.54 0.38 1.31e-5 Total body bone mineral density; TGCT cis rs57221529 0.545 rs55955015 chr5:575182 A/G cg09021430 chr5:549028 NA -0.37 -5.16 -0.42 9.7e-7 Lung disease severity in cystic fibrosis; TGCT cis rs9303401 0.659 rs34351230 chr17:56782555 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs57221529 0.600 rs11750269 chr5:666270 G/A cg09021430 chr5:549028 NA -0.4 -5.51 -0.44 2.02e-7 Lung disease severity in cystic fibrosis; TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs1205863 0.831 rs1205889 chr6:11948193 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs7772486 0.624 rs6930154 chr6:146025662 C/T cg13319975 chr6:146136371 FBXO30 0.52 4.74 0.39 5.77e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6998277 0.830 rs6981007 chr8:103598257 G/C cg10187029 chr8:103597600 NA 0.56 8.83 0.62 8.12e-15 Migraine; TGCT cis rs9611565 0.512 rs5751153 chr22:42156561 T/C cg06634786 chr22:41940651 POLR3H 0.86 8.01 0.58 7.16e-13 Vitiligo; TGCT cis rs367943 0.965 rs644154 chr5:112799080 G/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs9486715 1.000 rs6902835 chr6:97063005 C/G cg18709589 chr6:96969512 KIAA0776 -0.75 -6.75 -0.52 5.11e-10 Headache; TGCT cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg13397359 chr6:42928475 GNMT 0.73 6.81 0.52 3.7e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs35306767 0.669 rs2101051 chr10:1158791 G/T cg17861458 chr10:536227 DIP2C 0.23 4.44 0.37 1.99e-5 Eosinophil percentage of granulocytes; TGCT cis rs6912958 0.781 rs9450723 chr6:88226641 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.51 4.91 0.4 2.81e-6 Monocyte percentage of white cells; TGCT cis rs79349575 0.783 rs4255820 chr17:46996583 T/A cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs11096990 0.634 rs11096988 chr4:39265701 G/A cg20847110 chr4:39482781 LOC401127 0.16 4.53 0.38 1.38e-5 Cognitive function; TGCT cis rs2281636 1.000 rs10786569 chr10:101513585 G/A cg17885402 chr10:101492224 COX15;CUTC 0.58 4.51 0.38 1.45e-5 Obesity-related traits; TGCT cis rs7666738 0.678 rs7670805 chr4:99008763 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.86 0.4 3.46e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2806561 0.514 rs7414010 chr1:23543929 T/C cg19743168 chr1:23544995 NA 0.47 7.78 0.57 2.4e-12 Height; TGCT trans rs7726839 0.540 rs11750321 chr5:599196 C/T cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs9393777 0.513 rs9379905 chr6:26630990 G/A cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.51 -4.68 -0.39 7.36e-6 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.897 rs6781790 chr3:49044767 C/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.66 0.45 9.84e-8 Parkinson's disease; TGCT cis rs7246657 0.714 rs12972195 chr19:37752505 T/C cg24025825 chr19:37761650 NA -0.25 -4.51 -0.38 1.51e-5 Coronary artery calcification; TGCT cis rs2013441 1.000 rs2526467 chr17:20165054 T/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs10014284 chr4:98681951 G/C cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.41e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg02487422 chr3:49467188 NICN1 0.54 5.2 0.42 8.11e-7 Menarche (age at onset); TGCT cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg08859206 chr1:53392774 SCP2 0.41 5.98 0.47 2.19e-8 Monocyte count; TGCT cis rs1971762 0.583 rs1864448 chr12:54087856 T/G cg16917193 chr12:54089295 NA 1.35 17.63 0.85 1.39e-35 Height; TGCT cis rs9902453 0.780 rs3115093 chr17:28039755 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.9 9.42 0.65 3.28e-16 Coffee consumption (cups per day); TGCT cis rs896854 0.516 rs12679044 chr8:95891356 C/A cg16049864 chr8:95962084 TP53INP1 -0.57 -6.85 -0.52 3.02e-10 Type 2 diabetes; TGCT cis rs6906287 0.647 rs13192574 chr6:118875258 C/T cg21191810 chr6:118973309 C6orf204 0.26 4.5 0.38 1.51e-5 Electrocardiographic conduction measures; TGCT cis rs1799949 1.000 rs2298862 chr17:41176688 T/C cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs597539 0.652 rs611046 chr11:68631704 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.16 0.59 3.25e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3733585 0.699 rs4408959 chr4:9948868 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.43 -0.55 1.56e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs826838 0.935 rs980571 chr12:39127532 C/G cg13010199 chr12:38710504 ALG10B -0.64 -5.19 -0.42 8.26e-7 Heart rate; TGCT cis rs12478296 0.786 rs28802397 chr2:243049730 G/A cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs4566357 1.000 rs6436649 chr2:227923952 A/G cg11843606 chr2:227700838 RHBDD1 -0.58 -5.38 -0.44 3.51e-7 Coronary artery disease; TGCT cis rs77972916 0.518 rs55877805 chr2:43557597 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.54 -0.38 1.32e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs17826219 0.706 rs9905827 chr17:29192168 C/A cg14008862 chr17:28927542 LRRC37B2 0.73 4.7 0.39 6.79e-6 Body mass index; TGCT trans rs804280 0.517 rs7815179 chr8:11792048 C/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Myopia (pathological); TGCT cis rs12971120 1.000 rs12971120 chr18:72174023 A/G cg26446133 chr18:72167187 CNDP2 -0.34 -6.09 -0.48 1.31e-8 Refractive error; TGCT cis rs9581857 0.685 rs78595793 chr13:28031881 C/T cg22138327 chr13:27999177 GTF3A 0.8 5.58 0.45 1.47e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7226408 0.857 rs72885291 chr18:34449344 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT trans rs8073060 0.586 rs7214742 chr17:33981969 C/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg27535305 chr1:53392650 SCP2 0.23 4.47 0.37 1.72e-5 Monocyte count; TGCT cis rs10540 1.000 rs61876341 chr11:495892 C/G cg03352830 chr11:487213 PTDSS2 0.26 4.46 0.37 1.8e-5 Body mass index; TGCT cis rs4372836 0.658 rs7579321 chr2:28983166 T/C cg09522027 chr2:28974177 PPP1CB -0.68 -6.93 -0.53 2e-10 Body mass index; TGCT cis rs57221529 0.608 rs11749927 chr5:668842 C/T cg16624210 chr5:671434 TPPP 0.39 4.69 0.39 6.99e-6 Lung disease severity in cystic fibrosis; TGCT cis rs72781680 0.898 rs56413706 chr2:24086961 G/A cg08917208 chr2:24149416 ATAD2B 0.9 5.5 0.44 2.06e-7 Lymphocyte counts; TGCT cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg07424592 chr7:64974309 NA 0.62 6.08 0.48 1.37e-8 Calcium levels; TGCT cis rs172166 0.694 rs1150666 chr6:28123928 T/C cg10876282 chr6:28092338 ZSCAN16 0.49 4.53 0.38 1.37e-5 Cardiac Troponin-T levels; TGCT cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs931608 0.925 rs11085533 chr19:22612880 T/C cg23859931 chr19:22123797 NA 0.59 4.57 0.38 1.16e-5 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs77633900 0.614 rs1905694 chr15:76951772 T/C cg21673338 chr15:77095150 SCAPER -0.52 -4.94 -0.41 2.43e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs6840360 0.642 rs1596290 chr4:152410540 G/T cg17479576 chr4:152424074 FAM160A1 -0.57 -6.02 -0.48 1.85e-8 Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs7625448 chr3:53120766 C/A cg27565382 chr3:53032988 SFMBT1 0.41 4.6 0.38 1.01e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6952808 0.717 rs6967442 chr7:1926090 A/G cg04267008 chr7:1944627 MAD1L1 -0.35 -4.53 -0.38 1.34e-5 Bipolar disorder and schizophrenia; TGCT cis rs42648 0.720 rs9655741 chr7:89933874 C/G cg25739043 chr7:89950458 NA -0.62 -6.03 -0.48 1.73e-8 Homocysteine levels; TGCT cis rs7267979 0.932 rs2260997 chr20:25256266 A/C cg14121845 chr20:25566513 NINL -0.51 -5.72 -0.46 7.58e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg26354017 chr1:205819088 PM20D1 0.56 6.81 0.52 3.75e-10 Menarche (age at onset); TGCT cis rs813218 0.523 rs669676 chr3:99448852 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 5.13 0.42 1.07e-6 Orofacial clefts; TGCT cis rs7412746 0.503 rs72704639 chr1:150798335 A/C cg09365446 chr1:150670422 GOLPH3L 0.33 4.62 0.38 9.47e-6 Melanoma; TGCT cis rs1005277 0.541 rs2263163 chr10:38389887 G/A cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs1113500 0.541 rs9803640 chr1:108576267 A/C cg06207961 chr1:108661230 NA -0.24 -4.7 -0.39 6.83e-6 Growth-regulated protein alpha levels; TGCT cis rs7949030 0.626 rs11231145 chr11:62328854 G/A cg13298116 chr11:62369859 EML3;MTA2 0.64 9.42 0.65 3.17e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9653442 1.000 rs1160542 chr2:100832155 A/G cg07810366 chr2:100720526 AFF3 0.44 7.49 0.56 1.11e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs250677 1.000 rs250677 chr5:148433549 T/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.21 -0.49 7.22e-9 Breast cancer; TGCT cis rs9807989 0.507 rs1420105 chr2:103035119 A/G cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs11190604 1.000 rs11190613 chr10:102313997 C/T cg23241863 chr10:102295624 HIF1AN -0.7 -5.35 -0.43 4.03e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs208520 0.690 rs12202805 chr6:66703903 A/G cg07460842 chr6:66804631 NA -0.96 -10.26 -0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs7829975 0.742 rs7832968 chr8:8652889 G/A cg15556689 chr8:8085844 FLJ10661 0.71 6.47 0.5 2.08e-9 Mood instability; TGCT cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs17443541 0.507 rs4675697 chr2:200450808 C/T cg00055341 chr2:200446845 NA -0.33 -4.58 -0.38 1.12e-5 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.962 rs7273930 chr20:61666017 G/A cg08564027 chr20:61660810 NA 0.37 6.63 0.51 9.14e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7192750 0.586 rs4788576 chr16:71934105 C/T cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs4455778 0.580 rs4357241 chr7:49089468 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs854765 0.583 rs9635697 chr17:17870394 T/A cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs17001868 0.568 rs74424549 chr22:40736938 A/C cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs6952808 0.771 rs10950415 chr7:1914477 A/G cg22963979 chr7:1858916 MAD1L1 -0.35 -5.27 -0.43 5.75e-7 Bipolar disorder and schizophrenia; TGCT trans rs10506458 1.000 rs73128779 chr12:63441852 T/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.62 -0.56 5.8e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs986417 0.901 rs10151423 chr14:60996667 A/G cg27398547 chr14:60952738 C14orf39 1.47 10.91 0.7 7.87e-20 Gut microbiota (bacterial taxa); TGCT cis rs13256369 0.851 rs11786125 chr8:8564570 T/G cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs17001868 0.541 rs2092163 chr22:40810231 C/T cg07138101 chr22:40742427 ADSL 0.78 5.29 0.43 5.4e-7 Mammographic density (dense area); TGCT cis rs9314614 0.934 rs2980955 chr8:6694434 A/G cg27319216 chr8:6693540 XKR5 -0.28 -4.72 -0.39 6.37e-6 IgA nephropathy;White blood cell count (basophil); TGCT cis rs6121246 0.529 rs6060142 chr20:30178028 A/G cg13852791 chr20:30311386 BCL2L1 0.69 4.64 0.38 8.6e-6 Mean corpuscular hemoglobin; TGCT cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs13108904 0.901 rs2293634 chr4:1291711 T/G cg03303774 chr4:1407052 NA 0.3 4.89 0.4 3.09e-6 Obesity-related traits; TGCT cis rs3020736 0.500 rs4147641 chr22:42482502 C/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs3862435 0.572 rs2601186 chr15:90926921 A/G cg14166756 chr15:90894880 ZNF774 -0.32 -5.12 -0.42 1.14e-6 Response to exercise (triglyceride level interaction); TGCT cis rs9534288 0.956 rs962694 chr13:46619026 T/C cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs1018836 0.923 rs9643298 chr8:91552502 G/A cg16814680 chr8:91681699 NA -0.88 -9.81 -0.66 3.71e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs5769765 0.954 rs1569954 chr22:50244071 C/T cg15316289 chr22:50310904 ALG12;CRELD2 -0.37 -5.7 -0.46 8.42e-8 Schizophrenia; TGCT cis rs10493773 0.775 rs11161649 chr1:86165446 A/C cg17807903 chr1:86174739 ZNHIT6 -0.43 -6.18 -0.49 8.29e-9 Urate levels in overweight individuals; TGCT cis rs10504229 0.871 rs10504227 chr8:58162005 G/A cg22535103 chr8:58192502 C8orf71 -0.38 -4.7 -0.39 6.91e-6 Developmental language disorder (linguistic errors); TGCT cis rs35160687 0.901 rs12478575 chr2:86535314 C/G cg04877910 chr2:85804641 VAMP8 0.34 4.51 0.38 1.49e-5 Night sleep phenotypes; TGCT cis rs939658 0.728 rs12904323 chr15:79412583 A/C cg17916960 chr15:79447300 NA -0.46 -6.39 -0.5 3.11e-9 Refractive error; TGCT cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg01448562 chr3:133502909 NA -0.35 -7.2 -0.54 5.08e-11 Iron status biomarkers; TGCT cis rs9549260 0.755 rs2721067 chr13:41156708 C/T cg21288729 chr13:41239152 FOXO1 1.0 10.06 0.67 9.29e-18 Red blood cell count; TGCT trans rs77457752 0.690 rs75036580 chr9:13912781 C/T cg12973904 chr7:149457885 NA 0.46 7.39 0.55 1.88e-11 Breast cancer; TGCT cis rs6495367 1.000 rs4778882 chr15:79382019 A/G cg17916960 chr15:79447300 NA 0.38 5.46 0.44 2.52e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7923609 1.000 rs2393969 chr10:65140440 A/C cg08743896 chr10:65200160 JMJD1C -0.34 -4.58 -0.38 1.09e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs4808199 0.947 rs754255 chr19:19578890 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.2 0.42 8.14e-7 Nonalcoholic fatty liver disease; TGCT cis rs10114408 0.959 rs10120285 chr9:96652473 C/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs4654899 1.000 rs7554770 chr1:21481361 A/T cg01072550 chr1:21505969 NA -0.5 -8.08 -0.59 4.94e-13 Superior frontal gyrus grey matter volume; TGCT cis rs4746818 1.000 rs1506769 chr10:70959710 T/C cg11621586 chr10:70884670 VPS26A 1.2 10.28 0.68 2.63e-18 Left atrial antero-posterior diameter; TGCT cis rs7818688 0.697 rs77055525 chr8:95980583 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs12908161 1.000 rs35726233 chr15:85337800 C/T cg12863693 chr15:85201151 NMB 0.42 5.06 0.41 1.5e-6 Schizophrenia; TGCT cis rs72720396 0.789 rs12022460 chr1:91202257 A/G cg13456504 chr1:91191583 NA -0.61 -5.33 -0.43 4.51e-7 Morning vs. evening chronotype;Chronotype; TGCT cis rs57590327 0.503 rs13073613 chr3:81888512 C/A cg07356753 chr3:81810745 GBE1 -0.67 -6.19 -0.49 7.97e-9 Extraversion; TGCT cis rs11711311 1.000 rs921741 chr3:113444051 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.71 -6.58 -0.51 1.19e-9 IgG glycosylation; TGCT cis rs8062405 0.754 rs3859172 chr16:28566158 G/T cg09754948 chr16:28834200 ATXN2L 0.63 4.97 0.41 2.16e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs12580194 0.593 rs73326725 chr12:55749222 G/C cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs72700829 0.593 rs7526955 chr1:150990913 C/G cg00666978 chr1:150947442 LASS2 0.83 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs8077889 0.917 rs58283314 chr17:41905963 T/G cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs7296418 0.961 rs11608811 chr12:123529056 A/G cg00376283 chr12:123451042 ABCB9 0.83 7.72 0.57 3.27e-12 Platelet count; TGCT cis rs1043515 0.607 rs4795318 chr17:36949053 C/T cg09592244 chr17:37024020 NA 0.5 4.89 0.4 3.08e-6 Height; TGCT cis rs10174077 0.687 rs10172023 chr2:152476028 C/G cg06191203 chr2:152266755 RIF1 -0.62 -5.8 -0.46 5.06e-8 Squamous cell lung carcinoma; TGCT cis rs2463822 1.000 rs1881534 chr11:62085083 A/G cg23876832 chr11:62092739 NA 0.65 4.52 0.38 1.42e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs77372450 0.551 rs57823519 chr5:157101500 G/A cg12606933 chr5:157078573 SOX30 -0.42 -4.68 -0.39 7.47e-6 Bipolar disorder (body mass index interaction); TGCT trans rs34421088 0.560 rs2245250 chr8:11400680 G/A cg15556689 chr8:8085844 FLJ10661 -0.74 -7.05 -0.53 1.09e-10 Neuroticism; TGCT cis rs7617773 0.817 rs6801801 chr3:48326433 T/C cg11946769 chr3:48343235 NME6 0.72 6.16 0.48 9.39e-9 Coronary artery disease; TGCT cis rs67311347 1.000 rs897117 chr3:40437294 C/T cg13683864 chr3:40499215 RPL14 1.02 10.34 0.68 1.93e-18 Renal cell carcinoma; TGCT cis rs10131894 0.575 rs2159904 chr14:75432179 G/T cg06637938 chr14:75390232 RPS6KL1 0.59 5.07 0.41 1.42e-6 Coronary artery disease; TGCT cis rs4727027 0.870 rs1105261 chr7:148794442 T/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.52 0.38 1.43e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2439831 1.000 rs689826 chr15:43749916 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.56 0.45 1.56e-7 Lung cancer in ever smokers; TGCT cis rs6089829 0.925 rs6122087 chr20:61664553 T/C cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7937682 1.000 rs11213980 chr11:111562692 A/T cg09085632 chr11:111637200 PPP2R1B 0.92 7.9 0.58 1.31e-12 Primary sclerosing cholangitis; TGCT cis rs9916302 0.808 rs12943928 chr17:37611330 G/A cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs7953249 0.594 rs11065384 chr12:121423285 T/C cg02403541 chr12:121454288 C12orf43 -0.7 -6.33 -0.49 4.11e-9 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7100689 0.784 rs3802638 chr10:82179689 T/C cg01528321 chr10:82214614 TSPAN14 0.9 9.37 0.64 4.33e-16 Post bronchodilator FEV1; TGCT cis rs854765 0.552 rs6502624 chr17:17847936 G/A cg09796270 chr17:17721594 SREBF1 0.24 4.79 0.4 4.7e-6 Total body bone mineral density; TGCT cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs9517320 0.534 rs4772090 chr13:99150674 T/C cg20487152 chr13:99095054 FARP1 -0.24 -4.62 -0.38 9.58e-6 Longevity; TGCT cis rs9467773 1.000 rs6924838 chr6:26571756 C/T cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.98 10.79 0.7 1.55e-19 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.64 0.38 8.8e-6 Bipolar disorder; TGCT cis rs7917772 0.503 rs1536308 chr10:104288777 T/G cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs72781680 0.898 rs7569424 chr2:24036222 A/G cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs17345786 0.628 rs11718446 chr3:101552553 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.8 8.9 0.62 5.72e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs1023500 1.000 rs3752591 chr22:42339516 A/G cg04692870 chr22:42525206 CYP2D6 -0.34 -5.06 -0.41 1.47e-6 Schizophrenia; TGCT cis rs9611565 0.607 rs132792 chr22:42062822 C/T cg17554472 chr22:41940697 POLR3H 0.48 5.14 0.42 1.04e-6 Vitiligo; TGCT cis rs7772486 0.686 rs10872579 chr6:145966012 C/G cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.39e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3749237 1.000 rs11920900 chr3:49823024 G/C cg07636037 chr3:49044803 WDR6 0.61 5.32 0.43 4.68e-7 Resting heart rate; TGCT trans rs731174 0.592 rs1010805 chr1:38189142 A/C cg19725343 chr19:51830960 IGLON5 -0.63 -7.18 -0.54 5.57e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs10769945 0.592 rs1635155 chr11:1972919 G/T cg06503573 chr11:1949039 TNNT3 -0.26 -4.59 -0.38 1.08e-5 DNA methylation (variation); TGCT cis rs10744422 0.920 rs897393 chr12:123312051 A/G cg25930673 chr12:123319894 HIP1R 0.84 5.22 0.42 7.45e-7 Schizophrenia; TGCT cis rs7647973 0.925 rs4384984 chr3:49289878 T/G cg07636037 chr3:49044803 WDR6 0.67 5.41 0.44 3.15e-7 Menarche (age at onset); TGCT cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg24829409 chr8:58192753 C8orf71 -0.58 -5.51 -0.44 2.03e-7 Developmental language disorder (linguistic errors); TGCT cis rs3749237 0.595 rs6784820 chr3:49450864 C/T cg02487422 chr3:49467188 NICN1 -0.6 -6.31 -0.49 4.42e-9 Resting heart rate; TGCT cis rs1008375 0.931 rs3775926 chr4:17599837 G/A cg16339924 chr4:17578868 LAP3 0.83 7.1 0.54 8.37e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3772130 0.564 rs4420917 chr3:121567863 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.59 5.43 0.44 2.8e-7 Cognitive performance; TGCT cis rs2180341 0.960 rs9401952 chr6:127677027 A/C cg27446573 chr6:127587934 RNF146 1.14 10.91 0.7 7.51e-20 Breast cancer; TGCT cis rs909674 0.909 rs1557541 chr22:39851970 C/A cg01416388 chr22:39784598 NA -0.67 -6.0 -0.47 1.99e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs597539 0.652 rs557625 chr11:68634722 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4891159 0.548 rs690423 chr18:74117984 G/A cg24786174 chr18:74118243 ZNF516 0.71 15.7 0.82 2.91e-31 Longevity; TGCT cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs8014204 0.762 rs973879 chr14:75297727 T/C cg06637938 chr14:75390232 RPS6KL1 0.57 5.07 0.41 1.4e-6 Caffeine consumption; TGCT cis rs116095464 0.558 rs28636067 chr5:199415 G/A cg12570787 chr5:219185 SDHA;CCDC127 0.74 4.65 0.39 8.43e-6 Breast cancer; TGCT cis rs16866061 0.515 rs114968850 chr2:225352461 C/G cg12698349 chr2:225449008 CUL3 1.12 15.51 0.81 8.08e-31 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs36051895 0.632 rs11788164 chr9:5129395 A/G cg02405213 chr9:5042618 JAK2 -0.77 -10.84 -0.7 1.15e-19 Pediatric autoimmune diseases; TGCT cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs208515 0.518 rs12209790 chr6:66662965 T/C cg07460842 chr6:66804631 NA 0.83 8.65 0.61 2.18e-14 Exhaled nitric oxide levels; TGCT cis rs8044995 0.563 rs73615919 chr16:68398862 C/T cg05110241 chr16:68378359 PRMT7 -0.36 -4.48 -0.37 1.66e-5 Schizophrenia; TGCT cis rs8017423 0.608 rs12588149 chr14:90822676 G/A cg04374321 chr14:90722782 PSMC1 -0.54 -5.44 -0.44 2.71e-7 Mortality in heart failure; TGCT cis rs17331151 0.573 rs79664140 chr3:52866936 A/G cg15956490 chr3:53032818 SFMBT1 0.46 5.75 0.46 6.57e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1857353 0.901 rs79110498 chr1:75899763 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs477895 0.838 rs11605738 chr11:64013406 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 6.93 0.53 2.04e-10 Mean platelet volume; TGCT cis rs2354432 0.607 rs55918563 chr1:146718973 G/C cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg27454412 chr7:1067447 C7orf50 0.57 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10186029 0.657 rs11689895 chr2:213938553 G/T cg08319019 chr2:214017104 IKZF2 0.54 5.18 0.42 8.57e-7 Systemic sclerosis; TGCT cis rs9660992 0.710 rs1668869 chr1:205239779 G/C cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs3733585 0.725 rs10939636 chr4:9972640 T/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.68 -0.57 4.13e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13188771 0.690 rs352060 chr5:100877204 A/G cg18665594 chr5:101119420 NA 0.44 4.46 0.37 1.83e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs6952808 0.609 rs6944877 chr7:1952582 T/G cg22963979 chr7:1858916 MAD1L1 -0.39 -5.87 -0.47 3.76e-8 Bipolar disorder and schizophrenia; TGCT cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg24531977 chr5:56204891 C5orf35 -0.93 -8.51 -0.61 4.85e-14 Initial pursuit acceleration; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg24503407 chr1:205819492 PM20D1 0.59 7.87 0.58 1.48e-12 Menarche (age at onset); TGCT cis rs2299587 0.554 rs2073564 chr8:17743341 G/A cg04898035 chr8:17640624 MTUS1 -0.2 -4.67 -0.39 7.77e-6 Economic and political preferences; TGCT cis rs875971 0.862 rs1167399 chr7:65561877 G/A cg11764359 chr7:65958608 NA -0.56 -4.82 -0.4 4.1e-6 Aortic root size; TGCT cis rs10057188 1.000 rs10074749 chr5:77856454 G/A cg06873401 chr5:77792105 LHFPL2 -0.23 -4.67 -0.39 7.69e-6 Pulse pressure; TGCT cis rs910316 1.000 rs11845639 chr14:75570293 C/T cg08847533 chr14:75593920 NEK9 0.95 10.61 0.69 4.09e-19 Height; TGCT cis rs10782582 0.609 rs11161848 chr1:76367722 A/G cg10523679 chr1:76189770 ACADM -0.58 -5.26 -0.43 5.99e-7 Daytime sleep phenotypes; TGCT cis rs9394438 0.628 rs10947680 chr6:37543668 T/C cg00985040 chr6:37553208 NA -0.25 -4.96 -0.41 2.23e-6 IgG glycosylation; TGCT cis rs6582630 0.638 rs12831496 chr12:38552604 G/A cg26384229 chr12:38710491 ALG10B -0.53 -4.77 -0.39 5.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1403694 0.515 rs1648700 chr3:186449916 C/T cg12454167 chr3:186435060 KNG1 -0.46 -7.23 -0.54 4.46e-11 Blood protein levels; TGCT cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg15659132 chr6:26577336 NA 0.87 10.72 0.69 2.19e-19 Intelligence (multi-trait analysis); TGCT cis rs1403694 1.000 rs1403694 chr3:186439998 T/C cg12454167 chr3:186435060 KNG1 0.42 7.32 0.55 2.77e-11 Blood protein levels; TGCT cis rs8078723 0.802 rs9303283 chr17:38192633 A/G cg17467752 chr17:38218738 THRA 0.71 7.44 0.56 1.42e-11 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs4803455 0.565 rs1800470 chr19:41858921 G/A cg09537434 chr19:41945824 ATP5SL -0.52 -5.04 -0.41 1.63e-6 Migraine;Coronary artery disease; TGCT cis rs9486719 1.000 rs2092096 chr6:96870919 A/G cg18709589 chr6:96969512 KIAA0776 0.68 5.05 0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs9733 0.596 rs7418501 chr1:150711896 A/T cg04414720 chr1:150670196 GOLPH3L 0.35 4.66 0.39 8.05e-6 Tonsillectomy; TGCT cis rs208520 1.000 rs9453671 chr6:66991208 A/G cg07460842 chr6:66804631 NA 0.74 6.46 0.5 2.11e-9 Exhaled nitric oxide output; TGCT cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg14827481 chr10:134361889 INPP5A 0.3 4.87 0.4 3.27e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs524281 0.861 rs10896087 chr11:65924549 A/G cg00563793 chr11:65837595 PACS1 0.58 4.92 0.4 2.66e-6 Electroencephalogram traits; TGCT cis rs651907 0.640 rs771575 chr3:101619359 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.6 5.64 0.45 1.09e-7 Colorectal cancer; TGCT cis rs7312933 0.531 rs2708059 chr12:42851008 C/T cg19980929 chr12:42632907 YAF2 -0.42 -5.96 -0.47 2.44e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.62 -5.88 -0.47 3.62e-8 Bipolar disorder; TGCT cis rs7980687 0.506 rs1611973 chr12:123622731 C/G cg05973401 chr12:123451056 ABCB9 0.54 4.47 0.37 1.71e-5 Height;Educational attainment;Head circumference (infant); TGCT cis rs2249625 0.523 rs2496552 chr6:72853042 T/C cg24401219 chr6:72892597 RIMS1 -0.58 -4.96 -0.41 2.27e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg20891558 chr2:74357851 NA 0.62 9.13 0.63 1.62e-15 Gestational age at birth (maternal effect); TGCT cis rs9394841 0.692 rs9381097 chr6:41847800 A/G cg08135965 chr6:41755394 TOMM6 -0.51 -4.57 -0.38 1.14e-5 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs2288884 0.806 rs12460587 chr19:52586919 T/G cg13540795 chr19:52551618 ZNF432 -0.62 -5.33 -0.43 4.48e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs7267979 1.000 rs2258563 chr20:25273435 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8038465 0.550 rs11072431 chr15:73987642 T/A cg15420318 chr15:73925796 NPTN 0.6 6.03 0.48 1.74e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs950169 0.656 rs748455 chr15:85149575 T/C cg17173187 chr15:85201210 NMB 0.53 5.88 0.47 3.53e-8 Schizophrenia; TGCT cis rs4665809 1.000 rs2053367 chr2:26293413 T/C cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs7590720 1.000 rs6755934 chr2:216907198 C/A cg12620499 chr2:216877984 MREG 0.86 8.59 0.61 3.03e-14 Alcohol dependence; TGCT cis rs829880 0.858 rs733180 chr12:98842588 C/T cg25150519 chr12:98850993 NA 0.63 6.32 0.49 4.29e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4654899 0.758 rs2320826 chr1:21392096 A/C cg01072550 chr1:21505969 NA -0.57 -9.35 -0.64 4.68e-16 Superior frontal gyrus grey matter volume; TGCT cis rs1005277 0.505 rs7099777 chr10:38183569 A/C cg25427524 chr10:38739819 LOC399744 0.37 7.61 0.56 5.93e-12 Extrinsic epigenetic age acceleration; TGCT cis rs7819412 0.595 rs10503416 chr8:10987553 C/T cg21775007 chr8:11205619 TDH 0.56 5.21 0.42 7.76e-7 Triglycerides; TGCT cis rs1451375 0.657 rs12672526 chr7:50657695 C/T cg18232548 chr7:50535776 DDC 0.44 6.6 0.51 1.05e-9 Malaria; TGCT cis rs477895 0.639 rs35858916 chr11:63950529 T/G cg04317338 chr11:64019027 PLCB3 0.78 6.43 0.5 2.53e-9 Mean platelet volume; TGCT cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.73e-10 Menopause (age at onset); TGCT cis rs28374715 0.629 rs2118740 chr15:41577232 G/C cg18705301 chr15:41695430 NDUFAF1 -0.91 -13.14 -0.76 2.98e-25 Ulcerative colitis; TGCT trans rs7726839 0.540 rs7434 chr5:660804 A/G cg11887960 chr12:57824829 NA -1.13 -9.82 -0.66 3.45e-17 Obesity-related traits; TGCT cis rs6088580 0.634 rs2225837 chr20:33005634 C/T cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs1799949 0.894 rs36062488 chr17:41337472 C/T cg10047753 chr17:41438598 NA -0.77 -7.34 -0.55 2.46e-11 Menopause (age at onset); TGCT cis rs9660180 0.836 rs12038134 chr1:1703865 T/A cg23982607 chr1:1823379 GNB1 -0.55 -8.56 -0.61 3.69e-14 Body mass index; TGCT cis rs10031466 1.000 rs10031466 chr4:189015402 G/A cg14506195 chr4:188913931 NA -0.25 -4.77 -0.39 5.06e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9399135 0.967 rs11756988 chr6:135347595 A/G cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs71435601 0.657 rs12712940 chr2:21426743 C/A cg25035485 chr2:21266500 APOB -0.55 -4.68 -0.39 7.46e-6 Cholesterol, total; TGCT cis rs12681287 0.752 rs2917557 chr8:87314071 C/T cg27223183 chr8:87520930 FAM82B -0.83 -6.04 -0.48 1.67e-8 Caudate activity during reward; TGCT cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.71 0.39 6.54e-6 Colorectal cancer; TGCT cis rs62244186 0.659 rs9855433 chr3:44468065 C/A cg10263370 chr3:44754102 ZNF502 -0.39 -4.64 -0.38 8.7e-6 Depressive symptoms; TGCT trans rs6089829 0.962 rs1116450 chr20:61658210 T/C cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1215050 0.904 rs890469 chr4:98923293 T/C cg05340658 chr4:99064831 C4orf37 -0.46 -5.6 -0.45 1.32e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs6089829 0.962 rs3746747 chr20:61667631 T/C cg23505145 chr19:12996616 KLF1 0.81 8.7 0.62 1.74e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs17401966 0.931 rs912961 chr1:10356848 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.66 -0.39 8.14e-6 Hepatocellular carcinoma; TGCT cis rs3845702 0.668 rs12693215 chr2:180826007 A/C cg01881094 chr2:180872142 CWC22 -1.05 -6.78 -0.52 4.27e-10 Schizophrenia; TGCT cis rs798766 0.830 rs8389 chr4:1746844 A/T cg05874882 chr4:1763078 NA -0.33 -4.56 -0.38 1.2e-5 Bladder cancer;Urinary bladder cancer; TGCT cis rs6714710 0.603 rs12995673 chr2:98409046 G/A cg26665480 chr2:98280029 ACTR1B 0.69 6.34 0.49 3.96e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT trans rs4576506 0.536 rs13295330 chr9:31503145 T/C cg11445191 chr5:140227765 PCDHA6;PCDHA2;PCDHA1;PCDHA7;PCDHA5;PCDHA9;PCDHA3;PCDHA4;PCDHA8 0.98 6.69 0.51 6.76e-10 Psychosis and Alzheimer's disease; TGCT cis rs7917772 0.636 rs2253709 chr10:104542745 T/A cg05855489 chr10:104503620 C10orf26 -0.65 -5.1 -0.42 1.26e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs922182 0.763 rs1380841 chr15:64261912 T/C cg02919090 chr15:64263738 DAPK2 0.34 6.37 0.5 3.33e-9 Blood protein levels; TGCT cis rs1865760 0.566 rs10807006 chr6:26048752 C/A cg16482183 chr6:26056742 HIST1H1C 0.58 4.98 0.41 2.12e-6 Height; TGCT cis rs2235642 0.691 rs2281235 chr16:1603535 T/C cg10465839 chr16:1584050 IFT140;TMEM204 -0.31 -5.23 -0.43 7.02e-7 Coronary artery disease; TGCT cis rs8180040 0.903 rs12487736 chr3:47459679 C/T cg27129171 chr3:47204927 SETD2 0.65 7.61 0.56 6.03e-12 Colorectal cancer; TGCT cis rs904251 0.523 rs914348 chr6:37484729 G/A cg25019722 chr6:37503610 NA -0.51 -7.92 -0.58 1.16e-12 Cognitive performance; TGCT cis rs9300255 0.544 rs2049114 chr12:123657338 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.1e-7 Neutrophil percentage of white cells; TGCT cis rs12142240 0.698 rs72885198 chr1:46812888 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.77 -0.39 5.1e-6 Menopause (age at onset); TGCT cis rs12477438 0.520 rs11692699 chr2:99730657 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs903263 0.965 rs12723299 chr1:84590315 A/G cg09664975 chr1:84543551 PRKACB -0.49 -4.6 -0.38 1.01e-5 Breast cancer (male); TGCT cis rs9905704 0.647 rs33922512 chr17:57114148 C/G cg05425664 chr17:57184151 TRIM37 0.68 5.61 0.45 1.25e-7 Testicular germ cell tumor; TGCT cis rs17376456 0.569 rs2045021 chr5:93224222 G/A cg25358565 chr5:93447407 FAM172A -0.81 -6.5 -0.5 1.79e-9 Diabetic retinopathy; TGCT cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg13866156 chr1:1669148 SLC35E2 -0.22 -5.21 -0.42 7.6e-7 Body mass index; TGCT cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6089829 0.962 rs9679865 chr20:61666132 C/G cg02380750 chr20:61661411 NA 0.35 6.1 0.48 1.25e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg25767906 chr1:53392781 SCP2 -0.55 -6.64 -0.51 8.87e-10 Monocyte count; TGCT trans rs1814175 0.746 rs10839429 chr11:49906845 G/A cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.63 6.67 0.51 7.58e-10 Height; TGCT cis rs2832191 0.740 rs2832177 chr21:30478353 G/A cg08807101 chr21:30365312 RNF160 -0.67 -6.13 -0.48 1.08e-8 Dental caries; TGCT cis rs9303401 0.625 rs66508449 chr17:56691034 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs1577917 1.000 rs2166663 chr6:86593896 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.15 -0.42 9.91e-7 Response to antipsychotic treatment; TGCT cis rs9914544 0.564 rs11868500 chr17:18770254 A/G cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs9303401 0.659 rs62081315 chr17:56781468 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs6545883 0.895 rs4430924 chr2:61703856 A/G cg15711740 chr2:61764176 XPO1 -0.58 -5.23 -0.43 6.96e-7 Tuberculosis; TGCT cis rs17376456 0.877 rs10476596 chr5:93367074 C/T cg25358565 chr5:93447407 FAM172A -0.93 -8.37 -0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs9858213 1 rs9858213 chr3:49731861 G/T cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Educational attainment; TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg22997113 chr7:27170241 HOXA4 -0.44 -4.6 -0.38 1.05e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6901250 0.523 rs592669 chr6:117090944 T/C cg12892004 chr6:117198278 RFX6 0.37 4.77 0.39 5.09e-6 C-reactive protein levels; TGCT cis rs1865760 0.602 rs2157050 chr6:26020431 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.8 7.57 0.56 7.45e-12 Height; TGCT cis rs1949733 0.701 rs4696828 chr4:8455604 G/A cg13073564 chr4:8508604 NA 0.42 4.61 0.38 9.77e-6 Response to antineoplastic agents; TGCT cis rs1129187 0.755 rs2296804 chr6:42931261 C/G cg09436375 chr6:42928200 GNMT -0.41 -5.19 -0.42 8.34e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9372498 0.505 rs4416700 chr6:118975461 G/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.71 -0.39 6.4e-6 Diastolic blood pressure; TGCT cis rs7312933 0.558 rs7965743 chr12:42736822 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.72 -0.46 7.52e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4319547 0.910 rs6416298 chr12:123002143 C/T cg23029597 chr12:123009494 RSRC2 -0.32 -4.94 -0.41 2.45e-6 Body mass index; TGCT cis rs11239930 0.538 rs630630 chr1:146551926 T/C cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs4234284 0.556 rs13072737 chr3:126948835 C/T cg25436886 chr3:127056972 NA -0.47 -4.5 -0.37 1.54e-5 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs554111 0.660 rs12042978 chr1:21170811 T/C cg01072550 chr1:21505969 NA 0.33 4.94 0.41 2.43e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs12477438 1.000 rs17760953 chr2:99859863 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -6.39 -0.5 2.97e-9 Chronic sinus infection; TGCT cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg26818010 chr10:134567672 INPP5A -0.36 -5.16 -0.42 9.32e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6665290 0.935 rs1929862 chr1:227199718 G/A cg10327440 chr1:227177885 CDC42BPA -1.0 -20.65 -0.88 6.07e-42 Myeloid white cell count; TGCT cis rs916888 0.610 rs199453 chr17:44800946 C/T cg01570182 chr17:44337453 NA 0.76 7.36 0.55 2.22e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6546537 0.955 rs1396798 chr2:69887837 G/T cg10773587 chr2:69614142 GFPT1 -0.75 -6.49 -0.5 1.9e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs208520 1.000 rs12194996 chr6:66973366 G/C cg07460842 chr6:66804631 NA 0.77 6.82 0.52 3.49e-10 Exhaled nitric oxide output; TGCT cis rs9611565 0.512 rs5996063 chr22:42168767 G/A cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg07157834 chr1:205819609 PM20D1 0.49 8.61 0.61 2.77e-14 Menarche (age at onset); TGCT cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6748734 0.857 rs4675857 chr2:241842326 T/C cg04034577 chr2:241836375 C2orf54 -0.4 -6.35 -0.5 3.72e-9 Urinary metabolites; TGCT cis rs2115630 0.967 rs8027779 chr15:85255385 T/C cg12863693 chr15:85201151 NMB -0.33 -4.51 -0.38 1.48e-5 P wave terminal force; TGCT cis rs6430585 0.527 rs6753232 chr2:136436317 C/T cg07169764 chr2:136633963 MCM6 -0.99 -8.92 -0.63 4.97e-15 Corneal structure; TGCT cis rs6088580 0.542 rs6059882 chr20:33090167 T/C cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs7044106 0.762 rs4837789 chr9:123426256 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.63 6.68 0.51 7.09e-10 Hip circumference adjusted for BMI; TGCT trans rs57221529 0.766 rs12522140 chr5:587261 C/A cg25482853 chr8:67687455 SGK3 1.2 10.12 0.67 6.42e-18 Lung disease severity in cystic fibrosis; TGCT cis rs1215050 0.791 rs6838628 chr4:98809574 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.61 0.45 1.24e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11690935 0.959 rs6709156 chr2:172591944 T/C cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.51 -0.75 9.78e-24 Schizophrenia; TGCT cis rs3008870 0.755 rs2815368 chr1:67500778 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.48 0.61 5.61e-14 Lymphocyte percentage of white cells; TGCT cis rs9858542 0.537 rs34514189 chr3:49373045 A/G cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.57 0.38 1.18e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs11711311 1.000 rs7645473 chr3:113516187 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.64 -0.51 8.96e-10 IgG glycosylation; TGCT cis rs4455778 0.580 rs4276634 chr7:49118612 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs9473924 0.505 rs9463663 chr6:50902266 G/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs9325144 0.534 rs1843887 chr12:38692380 T/C cg26384229 chr12:38710491 ALG10B 0.66 6.12 0.48 1.11e-8 Morning vs. evening chronotype; TGCT cis rs10782582 0.609 rs1251584 chr1:76424440 C/T cg05598546 chr1:76251766 SNORD45C;RABGGTB -0.59 -5.28 -0.43 5.51e-7 Daytime sleep phenotypes; TGCT cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg03396347 chr1:1875803 NA -0.36 -6.51 -0.5 1.66e-9 Body mass index; TGCT cis rs3733585 0.673 rs4580649 chr4:9948461 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.23 -0.54 4.33e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9837602 0.529 rs1688774 chr3:99521108 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.71 0.52 6.1e-10 Breast cancer; TGCT cis rs637571 0.546 rs10791827 chr11:65596546 C/A cg04055107 chr11:65626734 MUS81;CFL1 -0.6 -5.89 -0.47 3.32e-8 Eosinophil percentage of white cells; TGCT cis rs3776081 0.600 rs4432875 chr5:149539527 G/A cg18424208 chr5:149546337 CDX1 -0.25 -4.48 -0.37 1.66e-5 Blood protein levels; TGCT cis rs17376456 0.597 rs7728825 chr5:93384594 T/C cg21475434 chr5:93447410 FAM172A -0.6 -5.65 -0.45 1.05e-7 Diabetic retinopathy; TGCT cis rs10504229 0.679 rs12679920 chr8:58051710 G/T cg11062466 chr8:58055876 NA 0.34 4.64 0.38 8.58e-6 Developmental language disorder (linguistic errors); TGCT cis rs2688608 0.967 rs9971040 chr10:75661162 G/C cg02947784 chr10:75434997 AGAP5 0.16 4.51 0.38 1.46e-5 Inflammatory bowel disease; TGCT cis rs950776 0.518 rs8025429 chr15:78836362 G/A cg06917634 chr15:78832804 PSMA4 -0.93 -9.08 -0.63 2.07e-15 Sudden cardiac arrest; TGCT cis rs12497850 0.864 rs7431857 chr3:48900347 G/A cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs9650657 0.547 rs11250099 chr8:10818657 C/T cg21775007 chr8:11205619 TDH 0.5 4.82 0.4 4.13e-6 Neuroticism; TGCT cis rs3733346 0.553 rs10008187 chr4:941017 C/T cg22718636 chr4:961658 DGKQ 0.46 4.47 0.37 1.77e-5 Sjögren's syndrome; TGCT cis rs9467773 1.000 rs28558133 chr6:26531433 G/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs6879260 1.000 rs10903252 chr5:179733934 T/C cg23221052 chr5:179740743 GFPT2 -0.36 -5.75 -0.46 6.7e-8 Height; TGCT cis rs1448094 0.511 rs11117042 chr12:86207547 G/T cg02569458 chr12:86230093 RASSF9 0.39 4.75 0.39 5.44e-6 Major depressive disorder; TGCT cis rs17376456 0.569 rs7729807 chr5:93104089 C/T cg21475434 chr5:93447410 FAM172A 0.61 4.97 0.41 2.17e-6 Diabetic retinopathy; TGCT cis rs992157 1.000 rs6736362 chr2:219115108 C/T cg00012203 chr2:219082015 ARPC2 0.76 8.17 0.59 3.03e-13 Colorectal cancer; TGCT cis rs72634258 0.554 rs4908705 chr1:7926401 C/T cg26816564 chr1:7831052 VAMP3 0.64 5.21 0.42 7.71e-7 Inflammatory bowel disease; TGCT cis rs6690583 0.573 rs75119114 chr1:85451385 A/C cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs9486715 0.830 rs2475023 chr6:96996833 G/A cg18709589 chr6:96969512 KIAA0776 -0.85 -8.33 -0.6 1.29e-13 Headache; TGCT cis rs72781680 0.898 rs17462558 chr2:24020812 T/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs2486012 0.678 rs2906460 chr1:44335323 A/G cg12908607 chr1:44402522 ARTN -0.69 -5.57 -0.45 1.49e-7 Intelligence (multi-trait analysis); TGCT cis rs9517302 0.615 rs3752973 chr13:99097509 G/A cg22223119 chr13:99095684 FARP1 -0.56 -6.11 -0.48 1.18e-8 Obesity-related traits; TGCT cis rs10504229 0.679 rs16921676 chr8:58052386 G/T cg21724239 chr8:58056113 NA 0.34 4.51 0.38 1.46e-5 Developmental language disorder (linguistic errors); TGCT cis rs11696845 0.712 rs6130685 chr20:43366730 T/G cg25301532 chr20:43378953 KCNK15 0.43 4.6 0.38 1.01e-5 Obesity-related traits; TGCT cis rs28595532 0.920 rs116062544 chr4:119735548 G/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg21724239 chr8:58056113 NA 0.47 5.05 0.41 1.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs941873 0.868 rs2181080 chr10:81121960 A/G cg09469691 chr10:81107165 PPIF 0.68 6.91 0.53 2.23e-10 Height; TGCT cis rs9926296 0.512 rs11076626 chr16:89865103 T/A cg26513180 chr16:89883248 FANCA 1.03 14.05 0.78 2.1e-27 Vitiligo; TGCT cis rs9527 0.830 rs11191440 chr10:104641511 G/A cg04362960 chr10:104952993 NT5C2 0.62 5.06 0.41 1.46e-6 Arsenic metabolism; TGCT cis rs7714584 1.000 rs11746108 chr5:150264622 C/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg01802117 chr1:53393560 SCP2 -0.4 -4.86 -0.4 3.44e-6 Monocyte count; TGCT cis rs9549367 0.713 rs9549352 chr13:113833221 A/G cg00898013 chr13:113819073 PROZ -0.55 -6.95 -0.53 1.83e-10 Platelet distribution width; TGCT cis rs9425326 0.508 rs3010055 chr1:183817289 A/C cg15569801 chr1:184197096 NA 0.15 5.25 0.43 6.37e-7 Antipsychotic drug-induced QTc interval change in schizophrenia; TGCT cis rs5167 0.781 rs2075619 chr19:45495682 A/G cg13119609 chr19:45449297 APOC2 0.23 4.81 0.4 4.29e-6 Blood protein levels; TGCT cis rs3733585 0.699 rs7699609 chr4:9961059 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3774830 0.658 rs171846 chr4:5428077 G/A cg26943120 chr4:5472116 STK32B -0.25 -5.78 -0.46 5.6e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs10114408 0.959 rs10821253 chr9:96653063 G/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2071303 0.502 rs9393686 chr6:26106601 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 6.17 0.48 8.75e-9 Intelligence (multi-trait analysis); TGCT trans rs797680 0.789 rs797671 chr1:93700363 C/A cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs790110 0.702 rs9820197 chr3:122352525 C/G cg18016254 chr3:122296505 PARP15 -0.44 -4.45 -0.37 1.86e-5 Acoustic startle blink response; TGCT cis rs1865760 0.566 rs2051544 chr6:26071093 C/T cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.19e-6 Height; TGCT cis rs11030122 0.702 rs10500590 chr11:3964724 T/C cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs10883723 0.668 rs12414407 chr10:104387019 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.8 -8.7 -0.62 1.68e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs11648796 0.680 rs11248946 chr16:768597 A/G cg00908189 chr16:619842 PIGQ 0.79 6.43 0.5 2.54e-9 Height; TGCT cis rs2204008 0.715 rs3899385 chr12:38169880 C/G cg26384229 chr12:38710491 ALG10B 0.86 7.68 0.57 4.17e-12 Bladder cancer; TGCT cis rs6840360 0.571 rs28454076 chr4:152520083 G/T cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs61867294 0.574 rs6584647 chr10:106711259 T/A cg08000847 chr10:105880925 C10orf78 0.48 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs9911578 0.967 rs12603238 chr17:57130785 C/T cg05425664 chr17:57184151 TRIM37 0.68 6.76 0.52 4.78e-10 Intelligence (multi-trait analysis); TGCT cis rs1018836 0.923 rs13254212 chr8:91582355 T/C cg16814680 chr8:91681699 NA -0.86 -9.06 -0.63 2.36e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9443645 0.901 rs9352664 chr6:79566162 G/T cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.645 rs7928714 chr11:49887622 G/A cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.6e-6 Menopause (age at onset); TGCT cis rs7220711 0.967 rs4793023 chr17:41800656 C/A cg26893861 chr17:41843967 DUSP3 0.56 5.02 0.41 1.76e-6 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs7937682 0.889 rs1784787 chr11:111486125 T/A cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs9640161 0.789 rs60283368 chr7:150023258 G/A cg17279839 chr7:150038598 RARRES2 0.43 4.6 0.38 1.02e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs11190604 0.767 rs10883478 chr10:102162852 C/T cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1045714 0.895 rs73043180 chr7:2645972 C/T cg17215154 chr7:2644645 IQCE 0.28 4.92 0.4 2.75e-6 Urate levels in lean individuals; TGCT cis rs9640161 0.702 rs11765692 chr7:150026567 C/T cg17279839 chr7:150038598 RARRES2 0.43 4.66 0.39 8.18e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs8180040 0.726 rs2305638 chr3:47046842 G/C cg27129171 chr3:47204927 SETD2 0.77 9.85 0.66 2.86e-17 Colorectal cancer; TGCT trans rs696279 0.967 rs697511 chr7:16700648 C/A cg14841483 chr5:131310671 ACSL6 0.38 6.79 0.52 4.05e-10 Mean platelet volume; TGCT cis rs9911578 0.967 rs3826353 chr17:57075299 C/T cg12560992 chr17:57184187 TRIM37 0.77 9.56 0.65 1.48e-16 Intelligence (multi-trait analysis); TGCT cis rs11671005 0.779 rs3794971 chr19:58985866 T/C cg18639983 chr19:58920768 ZNF584 0.34 4.67 0.39 7.6e-6 Mean platelet volume; TGCT cis rs853679 0.657 rs1778483 chr6:28240991 T/G cg18815343 chr6:28367644 ZSCAN12 -0.51 -5.14 -0.42 1.02e-6 Depression; TGCT cis rs12478296 0.901 rs6731775 chr2:242999443 T/C cg06360820 chr2:242988706 NA -0.57 -4.65 -0.39 8.52e-6 Obesity-related traits; TGCT cis rs4383453 0.539 rs55689356 chr3:123098203 T/C cg04890266 chr3:123102914 ADCY5 -0.5 -8.3 -0.6 1.48e-13 Gestational age at birth (maternal effect); TGCT cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg26818010 chr10:134567672 INPP5A -0.39 -5.53 -0.45 1.78e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7666738 0.830 rs10019087 chr4:99030211 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs453301 0.658 rs6986044 chr8:8874786 G/C cg00184457 chr8:8946301 NA -0.26 -4.71 -0.39 6.52e-6 Joint mobility (Beighton score); TGCT cis rs477895 1.000 rs11600990 chr11:64082807 C/T cg23719950 chr11:63933701 MACROD1 -0.59 -4.6 -0.38 1.01e-5 Mean platelet volume; TGCT cis rs7617773 0.780 rs4479622 chr3:48338173 C/T cg11946769 chr3:48343235 NME6 0.82 7.06 0.54 1.03e-10 Coronary artery disease; TGCT trans rs74910095 0.786 rs73761393 chr5:62940990 T/C cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs568617 1.000 rs641018 chr11:65655393 G/C cg04055107 chr11:65626734 MUS81;CFL1 0.57 5.22 0.42 7.39e-7 Crohn's disease; TGCT cis rs9674544 0.646 rs8069452 chr17:47140999 A/G cg10950924 chr17:47092072 IGF2BP1 0.33 4.54 0.38 1.3e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs11105298 0.891 rs10777184 chr12:89919568 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1018836 0.923 rs4495387 chr8:91650997 C/T cg16814680 chr8:91681699 NA -0.85 -8.91 -0.62 5.26e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs12142240 0.698 rs17357683 chr1:46815378 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs597539 0.617 rs669659 chr11:68635623 G/C cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9892942 1 rs9892942 chr17:27178761 C/T cg20469991 chr17:27169893 C17orf63 -0.7 -4.68 -0.39 7.4e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6938 0.534 rs1127796 chr15:75193004 C/T cg10253484 chr15:75165896 SCAMP2 0.58 5.34 0.43 4.23e-7 Breast cancer; TGCT cis rs986417 0.748 rs1955700 chr14:61046481 A/G cg27398547 chr14:60952738 C14orf39 1.42 10.64 0.69 3.42e-19 Gut microbiota (bacterial taxa); TGCT cis rs9611519 0.828 rs28814423 chr22:41452301 G/A cg03806693 chr22:41940476 POLR3H -0.67 -6.03 -0.48 1.73e-8 Neuroticism; TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg06942814 chr7:27170819 HOXA4 -0.39 -4.46 -0.37 1.8e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2404602 0.647 rs11072636 chr15:77185786 A/G cg23625390 chr15:77176239 SCAPER -0.38 -4.89 -0.4 3.05e-6 Blood metabolite levels; TGCT cis rs6912958 0.684 rs4707382 chr6:88320641 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -5.2 -0.42 7.9e-7 Monocyte percentage of white cells; TGCT cis rs6540559 0.673 rs6694552 chr1:209976459 A/C cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT cis rs2463822 1.000 rs2513071 chr11:62098387 A/C cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs909341 0.537 rs6011098 chr20:62398935 C/T cg14758556 chr20:62440591 NA -0.34 -4.77 -0.39 5.13e-6 Atopic dermatitis; TGCT cis rs10883723 0.810 rs2296585 chr10:104245549 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6831352 0.765 rs35361391 chr4:100069281 A/T cg12011299 chr4:100065546 ADH4 -0.46 -5.22 -0.42 7.38e-7 Alcohol dependence; TGCT cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 9.05e-28 Menopause (age at onset); TGCT cis rs7552404 1.000 rs4949872 chr1:76131392 C/G cg03433033 chr1:76189801 ACADM 0.84 10.12 0.67 6.34e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs854765 0.647 rs2974998 chr17:17995619 A/G cg04398451 chr17:18023971 MYO15A -0.38 -6.61 -0.51 1.04e-9 Total body bone mineral density; TGCT cis rs12541335 0.639 rs4872468 chr8:22179844 G/C cg26039829 chr8:22132926 PIWIL2 0.27 5.18 0.42 8.64e-7 Hypertriglyceridemia; TGCT cis rs9611565 0.625 rs2076199 chr22:41903743 G/T cg13695892 chr22:41940480 POLR3H -0.84 -8.44 -0.6 7.04e-14 Vitiligo; TGCT trans rs561341 0.609 rs7209493 chr17:30197323 A/G cg20587970 chr11:113659929 NA 0.65 8.07 0.59 5.07e-13 Hip circumference adjusted for BMI; TGCT cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg10047753 chr17:41438598 NA 0.95 9.5 0.65 2.09e-16 Menopause (age at onset); TGCT cis rs2153535 0.542 rs4440510 chr6:8471818 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.73 0.46 7.1e-8 Motion sickness; TGCT cis rs73058052 1.000 rs67546213 chr19:50082587 G/A cg09250473 chr19:50168907 IRF3;BCL2L12 0.77 5.31 0.43 4.93e-7 Fibrinogen levels; TGCT cis rs3020736 0.500 rs28791586 chr22:42500483 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12220238 1.000 rs7096553 chr10:75957835 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT trans rs57221529 0.545 rs55955015 chr5:575182 A/G cg11887960 chr12:57824829 NA 1.1 9.44 0.65 2.89e-16 Lung disease severity in cystic fibrosis; TGCT cis rs2439831 0.702 rs8033995 chr15:44013509 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.93 6.33 0.49 4.18e-9 Lung cancer in ever smokers; TGCT cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg20637647 chr7:64974828 NA 0.9 5.06 0.41 1.45e-6 Diabetic kidney disease; TGCT trans rs11722228 0.549 rs41268389 chr4:10099277 G/A cg26043149 chr18:55253948 FECH 1.16 11.2 0.71 1.55e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs7192750 0.586 rs2288029 chr16:71917058 G/A cg06353428 chr16:71660113 MARVELD3 0.83 6.97 0.53 1.65e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs796364 0.664 rs4673660 chr2:200915395 C/T cg17644776 chr2:200775616 C2orf69 0.28 4.52 0.38 1.41e-5 Schizophrenia; TGCT cis rs9486715 0.830 rs4425602 chr6:96893906 G/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs4478858 0.684 rs4949374 chr1:31754511 G/C cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT trans rs1908814 0.516 rs13279577 chr8:11793096 C/G cg15556689 chr8:8085844 FLJ10661 0.77 7.37 0.55 2.13e-11 Neuroticism; TGCT cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg25767906 chr1:53392781 SCP2 0.52 5.98 0.47 2.25e-8 Monocyte count; TGCT cis rs35306767 0.714 rs12783621 chr10:1083304 C/T cg26597838 chr10:835615 NA 0.47 5.38 0.43 3.58e-7 Eosinophil percentage of granulocytes; TGCT cis rs13188771 0.651 rs12523298 chr5:100903067 T/A cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs250677 1.000 rs36080 chr5:148430451 A/G cg18129178 chr5:148520854 ABLIM3 -0.42 -6.2 -0.49 7.79e-9 Breast cancer; TGCT cis rs901683 0.702 rs73292848 chr10:46169752 T/C cg09623279 chr10:45395734 NA -0.49 -5.14 -0.42 1.05e-6 Red blood cell traits;Mean corpuscular volume; TGCT cis rs6088580 0.602 rs6059840 chr20:33030405 G/A cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs9911578 1.000 rs8071280 chr17:57010225 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs57221529 0.563 rs4957057 chr5:569230 C/G cg09021430 chr5:549028 NA -0.42 -5.68 -0.45 9.25e-8 Lung disease severity in cystic fibrosis; TGCT cis rs988712 0.622 rs4922793 chr11:27729505 A/G cg10635145 chr11:27742435 BDNF -0.44 -6.37 -0.5 3.35e-9 Obesity; TGCT cis rs13177918 0.559 rs10447224 chr5:149834365 G/A cg14059543 chr5:149831962 NA -0.62 -7.86 -0.58 1.63e-12 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs17601876 0.814 rs28520437 chr15:51553277 C/T cg19946085 chr15:51559439 CYP19A1 -0.31 -4.76 -0.39 5.38e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs752010 0.523 rs10890160 chr1:42120011 A/G cg06885757 chr1:42089581 HIVEP3 0.26 4.73 0.39 6.1e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs6693567 0.545 rs1313568 chr1:150344180 C/G cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs7772486 0.875 rs2814873 chr6:146308932 T/C cg13319975 chr6:146136371 FBXO30 -0.53 -4.68 -0.39 7.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9527 0.615 rs11191489 chr10:104740568 C/A cg15744005 chr10:104629667 AS3MT -0.46 -5.37 -0.43 3.77e-7 Arsenic metabolism; TGCT cis rs2204008 0.715 rs12815986 chr12:38343869 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.25 0.55 3.99e-11 Bladder cancer; TGCT cis rs904251 0.522 rs882322 chr6:37484103 A/G cg08126542 chr6:37504118 NA -0.44 -6.47 -0.5 2.04e-9 Cognitive performance; TGCT trans rs1496653 0.602 rs34804976 chr3:23474436 T/G cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs3824867 0.920 rs4752836 chr11:47465095 T/C cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg24531977 chr5:56204891 C5orf35 0.75 7.33 0.55 2.57e-11 Initial pursuit acceleration; TGCT cis rs2282802 0.685 rs13359519 chr5:139654664 G/A cg01081189 chr5:139537190 NA 0.28 5.15 0.42 9.75e-7 Intelligence (multi-trait analysis); TGCT cis rs1577917 0.771 rs7742201 chr6:86432930 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.6 -5.31 -0.43 4.97e-7 Response to antipsychotic treatment; TGCT trans rs10506458 0.915 rs1463821 chr12:63402875 C/G cg22491629 chr6:157744540 C6orf35 0.96 9.02 0.63 2.91e-15 Hemostatic factors and hematological phenotypes; TGCT cis rs12989701 1.000 rs12989701 chr2:127887985 C/A cg08168897 chr2:127865431 BIN1 0.59 5.76 0.46 6.14e-8 Alzheimer's disease (late onset); TGCT cis rs6964587 0.626 rs6979235 chr7:91511776 T/C cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs6921919 0.583 rs35560946 chr6:28395437 C/T cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.19 -0.42 8.49e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6460942 0.908 rs78780802 chr7:12233216 T/C cg06484146 chr7:12443880 VWDE -0.52 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs4478858 0.735 rs4622114 chr1:31772571 A/G cg07478791 chr1:31886160 SERINC2 -0.52 -5.03 -0.41 1.67e-6 Alcohol dependence; TGCT cis rs9443189 0.570 rs661229 chr6:76293793 G/A cg01950844 chr6:76311363 SENP6 0.97 6.1 0.48 1.27e-8 Prostate cancer; TGCT cis rs6912958 0.559 rs183599 chr6:88061024 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.71 0.46 7.78e-8 Monocyte percentage of white cells; TGCT trans rs324780 0.566 rs3103502 chr12:83911511 C/T cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.42e-10 Vertical cup-disc ratio; TGCT cis rs3924048 0.574 rs11121931 chr1:12617009 G/A cg00291366 chr1:12616550 NA 0.33 5.14 0.42 1.05e-6 Optic cup area; TGCT cis rs113084984 0.771 rs12623299 chr2:11685558 A/G cg25804072 chr2:10829725 NOL10 0.52 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs9467773 0.844 rs2393669 chr6:26503873 C/T cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg19729930 chr2:74357872 NA 0.6 9.1 0.63 1.92e-15 Gestational age at birth (maternal effect); TGCT cis rs9303401 0.614 rs34920953 chr17:56589406 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.63 6.47 0.5 2.08e-9 Cognitive test performance; TGCT cis rs3812831 0.695 rs7995986 chr13:114938802 A/G cg06611532 chr13:114900021 NA 0.33 5.99 0.47 2.15e-8 Schizophrenia; TGCT cis rs1990950 0.933 rs11747685 chr5:156903590 C/T cg25387487 chr5:157003181 ADAM19 0.32 4.74 0.39 5.79e-6 Lung function (FEV1/FVC); TGCT cis rs2230307 0.536 rs554742 chr1:100512568 G/A cg24955406 chr1:100503596 HIAT1 0.74 4.86 0.4 3.41e-6 Carotid intima media thickness; TGCT cis rs11098499 0.754 rs1980026 chr4:120251643 C/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs7017914 0.875 rs3110251 chr8:71936974 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs3096299 0.933 rs2965934 chr16:89481229 C/G cg02187348 chr16:89574699 SPG7 0.49 4.71 0.39 6.63e-6 Multiple myeloma (IgH translocation); TGCT cis rs4820539 1.000 rs5751589 chr22:23475762 A/G cg21100191 chr22:23484243 RTDR1 -0.89 -10.79 -0.7 1.54e-19 Bone mineral density; TGCT cis rs67385638 0.802 rs72872555 chr11:5310169 G/A cg12559170 chr11:5275217 HBG2 0.44 7.98 0.58 8.2e-13 Hemoglobin levels; TGCT cis rs1205863 1.000 rs1205871 chr6:11945048 T/C cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs17376456 0.569 rs13186432 chr5:93336940 G/A cg25358565 chr5:93447407 FAM172A -0.63 -5.82 -0.46 4.71e-8 Diabetic retinopathy; TGCT cis rs6815814 0.950 rs5743565 chr4:38805983 T/C cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs7917772 0.628 rs4604806 chr10:104373904 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12478296 1.000 rs56102931 chr2:243039936 A/G cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs11711311 1.000 rs10212375 chr3:113471336 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs7809950 0.678 rs62483640 chr7:106900214 T/G cg23024343 chr7:107201750 COG5 -0.43 -5.81 -0.46 4.86e-8 Coronary artery disease; TGCT cis rs926938 0.505 rs2878573 chr1:115521602 A/G cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs1577917 0.917 rs12202170 chr6:86590386 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.42 -0.44 3.02e-7 Response to antipsychotic treatment; TGCT cis rs2970818 0.831 rs7304949 chr12:4609625 A/G cg02722637 chr12:4922070 KCNA6 0.31 5.7 0.46 8.32e-8 Phosphorus levels; TGCT cis rs10431058 0.708 rs537974 chr11:107466572 T/G cg18204760 chr11:107461044 ELMOD1;LOC643923 0.59 5.04 0.41 1.6e-6 Common traits (Other); TGCT cis rs9818758 0.607 rs9311439 chr3:49310408 A/G cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs35146811 0.735 rs1727140 chr7:99815399 T/A cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs9926296 0.529 rs7195906 chr16:89806347 A/T cg21285383 chr16:89894308 SPIRE2 0.43 6.53 0.51 1.51e-9 Vitiligo; TGCT cis rs7020830 0.867 rs55845273 chr9:37362219 C/T cg14294708 chr9:37120828 ZCCHC7 1.15 15.73 0.82 2.55e-31 Schizophrenia; TGCT cis rs1395 0.778 rs6749393 chr2:27451000 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.47 0.65 2.4e-16 Blood metabolite levels; TGCT cis rs185694 0.817 rs9315003 chr13:30896885 T/C cg07600127 chr13:30881527 KATNAL1 0.65 5.57 0.45 1.48e-7 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs7727544 0.581 rs10075801 chr5:131677642 A/G cg24060327 chr5:131705240 SLC22A5 -0.5 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs6450176 0.909 rs2448 chr5:53302354 T/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs17376456 0.504 rs6898507 chr5:93082343 C/T cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs9435341 0.965 rs12401598 chr1:107580533 C/A cg09367891 chr1:107599246 PRMT6 0.64 5.71 0.46 7.78e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs9560113 1.000 rs9560106 chr13:112179605 A/G cg14154082 chr13:112174009 NA 0.36 4.93 0.4 2.58e-6 Menarche (age at onset); TGCT cis rs7172809 0.599 rs74026912 chr15:77730856 G/A cg22256960 chr15:77711686 NA -0.51 -4.87 -0.4 3.32e-6 Glucose homeostasis traits; TGCT cis rs12615966 1.000 rs12615966 chr2:105378957 A/G cg16465502 chr2:105461796 NA -0.78 -5.01 -0.41 1.83e-6 Pancreatic cancer; TGCT cis rs2663905 0.611 rs1509560 chr15:81391713 T/G cg18028999 chr15:81426610 C15orf26 -0.54 -5.23 -0.42 7.14e-7 QT interval (drug interaction); TGCT cis rs10751667 0.643 rs11246344 chr11:933783 A/C cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs7772486 0.846 rs2748499 chr6:146315002 T/C cg23711669 chr6:146136114 FBXO30 0.87 9.39 0.64 3.74e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2816062 0.861 rs2745312 chr1:18904012 T/A cg18795169 chr1:18902165 NA -0.55 -11.27 -0.71 1.02e-20 Urate levels in lean individuals; TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs11971779 0.715 rs10954646 chr7:139061069 C/G cg07862535 chr7:139043722 LUC7L2 -0.6 -4.89 -0.4 3.03e-6 Diisocyanate-induced asthma; TGCT trans rs1814175 0.765 rs1794141 chr11:49914135 G/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs137603 0.602 rs137654 chr22:39732413 C/T cg17798944 chr22:39715225 SNORD43;RPL3 -0.64 -6.96 -0.53 1.77e-10 Primary biliary cholangitis; TGCT cis rs34172651 0.517 rs2547040 chr16:24736408 G/C cg06028605 chr16:24865363 SLC5A11 -0.42 -4.66 -0.39 8.11e-6 Intelligence (multi-trait analysis); TGCT cis rs11578119 0.933 rs4281371 chr1:170427536 A/G cg09767346 chr1:170501363 GORAB -0.72 -5.74 -0.46 6.97e-8 Male-pattern baldness; TGCT cis rs2749592 0.531 rs994804 chr10:37900140 A/C cg25427524 chr10:38739819 LOC399744 0.31 5.65 0.45 1.05e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs11648796 0.721 rs743987 chr16:769566 C/G cg07343612 chr16:622815 PIGQ -0.38 -5.24 -0.43 6.6e-7 Height; TGCT cis rs7829975 0.742 rs882462 chr8:8678530 G/A cg08975724 chr8:8085496 FLJ10661 0.53 4.82 0.4 4.03e-6 Mood instability; TGCT cis rs4730250 0.634 rs257371 chr7:106795043 C/A cg02696742 chr7:106810147 HBP1 -0.72 -5.89 -0.47 3.44e-8 Osteoarthritis; TGCT cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.29 -0.43 5.34e-7 Developmental language disorder (linguistic errors); TGCT cis rs9796 0.621 rs11858678 chr15:41467932 A/G cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.17 -0.54 5.94e-11 Menopause (age at onset); TGCT cis rs4886920 0.666 rs11629621 chr15:78080737 C/G cg25212270 chr15:78015279 NA 0.23 4.9 0.4 2.88e-6 Neuroticism; TGCT cis rs9372498 0.536 rs9489395 chr6:118758884 T/C cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs3008870 1.000 rs2755248 chr1:67492624 A/G cg11518657 chr1:67396239 MIER1 0.52 4.47 0.37 1.73e-5 Lymphocyte percentage of white cells; TGCT trans rs877282 0.945 rs71491311 chr10:791747 G/A cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs9928842 0.765 rs6564223 chr16:75225899 T/C cg09066997 chr16:75300724 BCAR1 0.27 4.44 0.37 1.93e-5 Alcoholic chronic pancreatitis; TGCT cis rs6740322 0.696 rs10188539 chr2:43484675 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -5.66 -0.45 9.75e-8 Coronary artery disease; TGCT cis rs929596 0.755 rs887829 chr2:234668570 A/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 0.33 5.48 0.44 2.31e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs6840360 0.571 rs62327275 chr4:152548238 G/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs1541995 0.789 rs35544332 chr15:96230473 G/A cg00882281 chr15:96346592 NA 0.3 4.76 0.39 5.28e-6 Photic sneeze reflex; TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg14159672 chr1:205819179 PM20D1 0.57 6.92 0.53 2.1e-10 Menarche (age at onset); TGCT cis rs7666738 0.830 rs1456208 chr4:98678563 C/T cg17366294 chr4:99064904 C4orf37 0.62 6.4 0.5 2.94e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg01448562 chr3:133502909 NA -0.26 -4.71 -0.39 6.44e-6 Iron status biomarkers; TGCT cis rs9993613 0.808 rs12648992 chr4:73431560 T/C cg15102770 chr4:73434591 ADAMTS3 0.51 4.57 0.38 1.16e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs7666738 0.546 rs1813970 chr4:98887167 A/G cg05340658 chr4:99064831 C4orf37 -0.58 -6.02 -0.48 1.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10840270 1.000 rs10840270 chr11:9629553 C/G cg03787988 chr11:10602522 MRVI1 0.18 4.62 0.38 9.47e-6 Bacteremia; TGCT cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg17179660 chr6:151773299 C6orf211;RMND1 -0.51 -4.62 -0.38 9.45e-6 Menarche (age at onset); TGCT cis rs28595532 0.920 rs115675321 chr4:119742153 A/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs28595532 1.000 rs114682099 chr4:119702004 C/T cg14228332 chr4:119757509 SEC24D 1.02 5.06 0.41 1.47e-6 Cannabis dependence symptom count; TGCT cis rs2242116 0.796 rs7645278 chr3:46974100 A/C cg02527881 chr3:46936655 PTH1R -0.32 -6.03 -0.48 1.77e-8 Birth weight; TGCT trans rs1005277 0.579 rs2474571 chr10:38384639 T/G cg17830980 chr10:43048298 ZNF37B -0.85 -10.91 -0.7 7.78e-20 Extrinsic epigenetic age acceleration; TGCT cis rs2797780 0.964 rs2797782 chr6:37504036 T/C cg00985040 chr6:37553208 NA 0.24 4.57 0.38 1.18e-5 Systemic lupus erythematosus; TGCT cis rs73198271 0.628 rs11783707 chr8:8589609 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.33 -5.48 -0.44 2.3e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs708547 0.836 rs1315005 chr4:57858237 C/G cg25525207 chr4:57843836 C4orf14;POLR2B -0.55 -5.03 -0.41 1.71e-6 Response to bleomycin (chromatid breaks); TGCT cis rs7258465 0.897 rs1043327 chr19:18554972 A/G cg22489759 chr19:18572700 ELL 0.2 4.59 0.38 1.05e-5 Breast cancer; TGCT cis rs9399137 0.507 rs6940878 chr6:135366309 G/A cg24558204 chr6:135376177 HBS1L 0.46 4.57 0.38 1.15e-5 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.8e-6 Obesity-related traits; TGCT cis rs1552244 0.688 rs7645137 chr3:10020549 A/AT cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.5 -0.5 1.76e-9 Alzheimer's disease; TGCT cis rs112591243 0.570 rs117783236 chr21:47971219 A/T cg10657630 chr21:48055338 PRMT2 1.05 5.16 0.42 9.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs317689 0.680 rs315140 chr12:69790780 A/T cg14784868 chr12:69753453 YEATS4 0.54 4.58 0.38 1.11e-5 Response to diuretic therapy; TGCT cis rs539096 0.624 rs653953 chr1:44083015 G/A cg12908607 chr1:44402522 ARTN -0.45 -4.99 -0.41 1.97e-6 Intelligence (multi-trait analysis); TGCT cis rs669446 0.527 rs667676 chr1:44082216 G/A cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs55823223 0.564 rs936391 chr17:73847799 A/G cg10935138 chr17:73851978 WBP2 -0.78 -7.49 -0.56 1.14e-11 Psoriasis; TGCT cis rs9325144 0.647 rs12424190 chr12:39111206 A/T cg26384229 chr12:38710491 ALG10B -0.57 -5.3 -0.43 5.16e-7 Morning vs. evening chronotype; TGCT cis rs4918072 0.876 rs4918069 chr10:105654391 T/G cg11005552 chr10:105648138 OBFC1 0.41 5.4 0.44 3.29e-7 Coronary artery disease; TGCT cis rs7208859 0.673 rs55904046 chr17:29215391 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7208859 0.623 rs9897728 chr17:29108804 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11122272 0.615 rs1465740 chr1:231495255 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.73 -6.89 -0.53 2.51e-10 Hemoglobin concentration; TGCT cis rs17711722 0.701 rs781145 chr7:65440370 A/C cg00343986 chr7:65444356 GUSB 0.26 5.95 0.47 2.56e-8 Calcium levels; TGCT cis rs7772486 0.817 rs9322047 chr6:146400394 G/A cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9788682 1.000 rs12441354 chr15:78821016 G/A cg24631222 chr15:78858424 CHRNA5 0.93 7.96 0.58 9.55e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7615952 0.932 rs7630077 chr3:125649676 T/C cg05084668 chr3:125655381 ALG1L -0.75 -6.07 -0.48 1.43e-8 Blood pressure (smoking interaction); TGCT cis rs6665290 0.904 rs3768425 chr1:227178127 A/G cg10327440 chr1:227177885 CDC42BPA -1.01 -20.94 -0.88 1.57e-42 Myeloid white cell count; TGCT cis rs2201728 0.967 rs34397848 chr4:100147247 A/G cg07219303 chr4:100140905 ADH6 -0.35 -5.22 -0.42 7.29e-7 Cardiac Troponin-T levels; TGCT cis rs7772486 0.875 rs10457792 chr6:146412415 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs28785552 1.000 rs28785552 chr19:53234161 G/A cg10871876 chr19:53194124 ZNF83 0.6 8.53 0.61 4.35e-14 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs11190604 1.000 rs10883513 chr10:102316964 A/G cg23241863 chr10:102295624 HIF1AN 0.68 4.89 0.4 3.08e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7914558 0.966 rs1971589 chr10:104744406 A/G cg05855489 chr10:104503620 C10orf26 0.51 4.53 0.38 1.39e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs611744 0.631 rs627392 chr8:109254677 C/T cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs12477438 1.000 rs995617 chr2:99857904 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.76 5.79 0.46 5.47e-8 Chronic sinus infection; TGCT cis rs2439831 0.850 rs7168158 chr15:44050376 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs8013055 0.846 rs10139300 chr14:105974501 A/G cg25008857 chr14:105974488 NA 0.27 4.65 0.39 8.35e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs3008870 1.000 rs3008859 chr1:67390999 G/C cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg05665937 chr4:1216051 CTBP1 0.22 4.5 0.37 1.53e-5 Obesity-related traits; TGCT cis rs909674 0.524 rs5750821 chr22:39825492 A/T cg02038168 chr22:39784481 NA -0.79 -6.79 -0.52 4.07e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg11062466 chr8:58055876 NA 0.38 4.5 0.37 1.56e-5 Developmental language disorder (linguistic errors); TGCT cis rs4253772 0.550 rs6007779 chr22:46678615 A/C cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.67 4.62 0.38 9.61e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs6570726 0.846 rs6914304 chr6:145921017 T/C cg23711669 chr6:146136114 FBXO30 0.83 8.64 0.61 2.4e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs7312933 0.645 rs12049942 chr12:42587052 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10114408 0.877 rs10739961 chr9:96647692 G/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6840360 0.550 rs12651635 chr4:152557786 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.851 rs4809460 chr20:61661355 T/C cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT trans rs3857536 0.505 rs208459 chr6:66911055 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -7.75 -0.57 2.85e-12 Blood trace element (Cu levels); TGCT cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg06601766 chr17:61851465 DDX42;CCDC47 -0.53 -4.59 -0.38 1.06e-5 Height; TGCT cis rs4808199 0.895 rs8105984 chr19:19374068 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.14 0.42 1.03e-6 Nonalcoholic fatty liver disease; TGCT cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.960 rs11868459 chr17:29458197 C/T cg24425628 chr17:29625626 OMG;NF1 0.46 7.25 0.55 3.92e-11 Hip circumference; TGCT cis rs9650657 0.707 rs10098699 chr8:10676756 C/T cg27411982 chr8:10470053 RP1L1 -0.23 -5.19 -0.42 8.48e-7 Neuroticism; TGCT cis rs12220238 1.000 rs11000922 chr10:75969305 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg11905131 chr22:24372483 LOC391322 0.69 5.55 0.45 1.68e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2243480 1.000 rs316330 chr7:65605372 C/A cg20637647 chr7:64974828 NA 0.89 4.77 0.39 4.98e-6 Diabetic kidney disease; TGCT cis rs6460942 0.915 rs62448593 chr7:12436845 G/C cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs981844 0.775 rs1020704 chr4:154736494 C/T cg14289246 chr4:154710475 SFRP2 1.01 9.01 0.63 3.12e-15 Response to statins (LDL cholesterol change); TGCT cis rs155076 0.666 rs2015241 chr13:21888254 A/G cg11317459 chr13:21872234 NA 1.32 13.31 0.77 1.2e-25 White matter hyperintensity burden; TGCT cis rs10984561 0.881 rs77882033 chr9:122250600 C/T cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs751728 1.000 rs4713682 chr6:33757047 G/C cg00334056 chr6:33755658 LEMD2 -0.25 -4.55 -0.38 1.24e-5 Crohn's disease; TGCT cis rs7772486 0.727 rs11155442 chr6:146140725 T/C cg13319975 chr6:146136371 FBXO30 -0.52 -4.65 -0.39 8.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4819052 0.851 rs9979545 chr21:46679805 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9322193 0.923 rs9322204 chr6:149957183 A/C cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs514406 0.861 rs562182 chr1:53270010 C/T cg24675658 chr1:53192096 ZYG11B -0.73 -8.2 -0.59 2.62e-13 Monocyte count; TGCT cis rs67460515 0.892 rs7648279 chr3:160979646 G/A cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT cis rs10782582 0.609 rs72979226 chr1:76302222 C/A cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs801193 1.000 rs2055682 chr7:66260289 A/G cg18876405 chr7:65276391 NA 0.38 5.83 0.46 4.48e-8 Aortic root size; TGCT cis rs9807989 0.507 rs6710034 chr2:103023678 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT trans rs4332037 0.539 rs55773130 chr7:2070554 T/C cg10840412 chr1:235813424 GNG4 0.95 6.94 0.53 1.97e-10 Bipolar disorder; TGCT cis rs79839061 0.562 rs10516158 chr4:942439 A/G cg07828340 chr4:882639 GAK -0.32 -4.62 -0.38 9.63e-6 Intelligence (multi-trait analysis); TGCT cis rs1843834 1.000 rs1565072 chr2:225545245 C/T cg22455342 chr2:225449267 CUL3 -0.75 -7.41 -0.55 1.73e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs6952808 0.501 rs3778999 chr7:2180885 G/A cg22963979 chr7:1858916 MAD1L1 -0.38 -5.96 -0.47 2.38e-8 Bipolar disorder and schizophrenia; TGCT trans rs4824093 0.610 rs4141437 chr22:50243719 C/G cg09872104 chr7:134855509 C7orf49 0.91 7.33 0.55 2.66e-11 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs11734570 0.581 rs73811715 chr4:38590569 A/C cg18361445 chr4:38666374 KLF3;FLJ13197 0.63 4.61 0.38 9.67e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs860554 0.672 rs866215 chr1:201264853 T/C cg01022117 chr1:201258280 PKP1 0.34 5.04 0.41 1.61e-6 Panic disorder; TGCT cis rs854624 0.892 rs1734961 chr17:34335511 C/G cg02022384 chr17:34097390 MMP28 -0.5 -4.59 -0.38 1.09e-5 Blood protein levels; TGCT cis rs9486719 0.843 rs2499797 chr6:96848669 C/T cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs13242816 1.000 rs34652384 chr7:116157011 T/C cg02799643 chr7:116139180 CAV2 -0.44 -5.54 -0.45 1.74e-7 P wave duration; TGCT cis rs7959452 0.535 rs2305641 chr12:69646914 C/T cg11871910 chr12:69753446 YEATS4 0.62 6.22 0.49 6.95e-9 Blood protein levels; TGCT cis rs2718812 0.792 rs1867503 chr3:133410648 G/A cg16414030 chr3:133502952 NA 0.39 5.22 0.42 7.17e-7 Iron status biomarkers; TGCT cis rs896854 0.517 rs1011795 chr8:95951073 G/A cg16049864 chr8:95962084 TP53INP1 -0.54 -5.95 -0.47 2.54e-8 Type 2 diabetes; TGCT cis rs9549260 0.755 rs4943797 chr13:41201633 A/G cg21288729 chr13:41239152 FOXO1 -0.96 -9.96 -0.67 1.56e-17 Red blood cell count; TGCT cis rs1903068 0.853 rs28680424 chr4:56009245 T/C cg16572876 chr4:56024045 NA 0.44 4.87 0.4 3.29e-6 Endometriosis; TGCT cis rs854765 0.583 rs5002487 chr17:17832460 A/G cg09796270 chr17:17721594 SREBF1 0.26 5.37 0.43 3.76e-7 Total body bone mineral density; TGCT cis rs7226408 0.857 rs9675466 chr18:34502792 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs11252926 0.507 rs4881199 chr10:428090 C/G cg18196295 chr10:418757 DIP2C 0.31 5.21 0.42 7.57e-7 Psychosis in Alzheimer's disease; TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg23034840 chr1:205782522 SLC41A1 -0.63 -5.9 -0.47 3.29e-8 Monocyte percentage of white cells; TGCT cis rs769267 0.930 rs2288852 chr19:19605348 T/C cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs1891275 0.515 rs10786010 chr10:93443773 G/A cg07889827 chr10:93443413 NA -0.33 -6.99 -0.53 1.53e-10 Intelligence (multi-trait analysis); TGCT cis rs1129187 0.935 rs9462859 chr6:42946943 G/A cg17345569 chr6:42928274 GNMT -0.44 -4.5 -0.37 1.55e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs473651 0.935 rs508483 chr2:239339709 T/C cg08773314 chr2:239334832 ASB1 0.48 8.13 0.59 3.65e-13 Multiple system atrophy; TGCT cis rs877282 0.629 rs78997110 chr10:764388 A/G cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs7223966 0.960 rs2854222 chr17:61939015 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 5.17 0.42 9.21e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs17102423 1.000 rs4902364 chr14:65602006 G/A cg11161011 chr14:65562177 MAX -0.49 -6.7 -0.52 6.46e-10 Obesity-related traits; TGCT cis rs319204 0.918 rs319169 chr5:146290938 G/C cg25021259 chr5:146258546 PPP2R2B 0.35 4.48 0.37 1.65e-5 Schizophrenia; TGCT cis rs1005277 0.505 rs10827836 chr10:38215441 A/G cg25427524 chr10:38739819 LOC399744 0.38 7.67 0.57 4.25e-12 Extrinsic epigenetic age acceleration; TGCT cis rs3752962 0.588 rs903164 chr17:1939502 G/A cg24156229 chr17:1948635 NA -0.37 -7.11 -0.54 8.07e-11 Itch intensity from mosquito bite; TGCT cis rs9814567 1.000 rs7433991 chr3:134312292 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2243480 1.000 rs6958420 chr7:65751171 A/G cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs17401966 0.931 rs17410217 chr1:10371854 A/G cg19773385 chr1:10388646 KIF1B -0.23 -4.8 -0.4 4.51e-6 Hepatocellular carcinoma; TGCT cis rs17253792 0.822 rs75555677 chr14:56096429 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7772486 0.727 rs10447449 chr6:146138707 A/G cg13319975 chr6:146136371 FBXO30 -0.52 -4.7 -0.39 6.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9948 0.655 rs2280356 chr2:97366324 C/T cg01990225 chr2:97406019 LMAN2L 0.94 5.33 0.43 4.44e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9818758 0.607 rs9862483 chr3:49195441 G/A cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs3812049 0.784 rs7734927 chr5:127453735 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.66 6.27 0.49 5.59e-9 Lymphocyte counts;Red cell distribution width; TGCT cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg06238570 chr21:40685208 BRWD1 -0.79 -8.7 -0.62 1.7e-14 Cognitive function; TGCT cis rs2721195 0.845 rs3757966 chr8:145744618 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 0.88 9.6 0.65 1.17e-16 Age at first birth; TGCT cis rs6089829 0.925 rs11086152 chr20:61664656 T/C cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs8017423 0.935 rs11626869 chr14:90788985 A/G cg04374321 chr14:90722782 PSMC1 -0.71 -6.76 -0.52 4.87e-10 Mortality in heart failure; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg01171360 chr6:293285 DUSP22 0.71 7.25 0.55 3.87e-11 Menopause (age at onset); TGCT cis rs288326 0.561 rs75139715 chr2:183890660 T/A cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs4654899 0.931 rs10799669 chr1:21172501 T/C cg01072550 chr1:21505969 NA 0.47 7.4 0.55 1.83e-11 Superior frontal gyrus grey matter volume; TGCT cis rs7208859 0.524 rs73263982 chr17:28920624 T/C cg19761014 chr17:28927070 LRRC37B2 0.56 4.81 0.4 4.32e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2580764 0.566 rs2968827 chr2:55297629 C/G cg09592903 chr2:55203963 RTN4 0.25 5.64 0.45 1.09e-7 Mean platelet volume; TGCT cis rs889312 0.500 rs832552 chr5:56113850 A/C cg12311346 chr5:56204834 C5orf35 0.44 4.59 0.38 1.09e-5 Breast cancer;Breast cancer (early onset); TGCT cis rs10782582 0.593 rs6673786 chr1:76149637 C/T cg03433033 chr1:76189801 ACADM -0.64 -7.35 -0.55 2.29e-11 Daytime sleep phenotypes; TGCT cis rs78487399 0.908 rs10186307 chr2:43839896 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.64 4.63 0.38 8.92e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10791097 0.765 rs7943757 chr11:130716157 C/T cg05962950 chr11:130786565 SNX19 0.71 7.48 0.56 1.2e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9611565 0.694 rs5758324 chr22:41787950 G/T cg03806693 chr22:41940476 POLR3H -1.02 -11.06 -0.7 3.33e-20 Vitiligo; TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg21280719 chr6:42927975 GNMT -0.37 -4.61 -0.38 9.86e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9640161 0.742 rs2108852 chr7:150019628 T/C cg10018233 chr7:150070692 REPIN1 0.33 4.74 0.39 5.68e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs7666738 0.830 rs7669407 chr4:98750251 G/A cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.754 rs9390356 chr6:146118983 A/T cg13319975 chr6:146136371 FBXO30 0.58 5.24 0.43 6.75e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs10504229 0.596 rs6991216 chr8:58115586 T/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs4851254 0.961 rs13022707 chr2:100734946 C/A cg23118464 chr2:100721844 AFF3 0.67 4.9 0.4 2.93e-6 Intelligence (multi-trait analysis); TGCT cis rs9611519 0.780 rs9611546 chr22:41698542 C/G cg06634786 chr22:41940651 POLR3H -0.64 -5.99 -0.47 2.08e-8 Neuroticism; TGCT cis rs7178572 0.568 rs12905951 chr15:77649431 G/A cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT trans rs2727020 0.553 rs10839295 chr11:49527345 A/C cg03929089 chr4:120376271 NA -0.66 -7.62 -0.56 5.75e-12 Coronary artery disease; TGCT cis rs17433780 0.808 rs12122780 chr1:89508916 T/C cg09516651 chr1:89888402 LOC400759 0.26 4.94 0.41 2.48e-6 Carotid intima media thickness; TGCT cis rs6430585 0.591 rs1374330 chr2:136420908 A/C cg07169764 chr2:136633963 MCM6 1.09 9.79 0.66 4.14e-17 Corneal structure; TGCT cis rs9517313 0.591 rs9554480 chr13:99221138 T/A cg07423050 chr13:99094983 FARP1 -0.23 -4.48 -0.37 1.69e-5 Neuroticism; TGCT cis rs10504229 1.000 rs59797486 chr8:58174435 T/C cg24829409 chr8:58192753 C8orf71 -0.54 -5.17 -0.42 9.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs11209002 0.567 rs983110 chr1:67539215 A/T cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg03264133 chr6:25882463 NA -0.66 -6.11 -0.48 1.19e-8 Intelligence (multi-trait analysis); TGCT cis rs1577917 0.727 rs9351065 chr6:86360428 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT trans rs7618501 0.635 rs34080578 chr3:50026029 A/C cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.9 0.66 2.18e-17 Intelligence (multi-trait analysis); TGCT cis rs1994135 0.594 rs10772096 chr12:33732869 A/G cg06521331 chr12:34319734 NA -0.3 -4.71 -0.39 6.63e-6 Resting heart rate; TGCT cis rs2658782 0.826 rs1975820 chr11:93081815 G/A cg18152523 chr11:93063302 CCDC67 -0.67 -5.19 -0.42 8.29e-7 Pulmonary function decline; TGCT cis rs2204008 0.567 rs2703685 chr12:38081423 G/C cg26384229 chr12:38710491 ALG10B 0.58 4.96 0.41 2.24e-6 Bladder cancer; TGCT cis rs68170813 0.559 rs17428126 chr7:106897037 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs6665290 0.935 rs11588904 chr1:227196211 T/C cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs9926296 0.656 rs2376882 chr16:89827002 T/C cg01719998 chr16:89642051 CPNE7 -0.44 -4.48 -0.37 1.69e-5 Vitiligo; TGCT cis rs9911578 1.000 rs11869828 chr17:56609525 G/A cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs11190604 0.767 rs4919459 chr10:102200371 C/T cg16005271 chr10:102321736 NA 0.46 4.68 0.39 7.39e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6840360 1.000 rs4571 chr4:152592191 T/C cg17479576 chr4:152424074 FAM160A1 -0.48 -5.06 -0.41 1.47e-6 Intelligence (multi-trait analysis); TGCT cis rs4252435 0.522 rs4252427 chr7:142623357 C/T cg09833174 chr7:143059591 FAM131B 0.99 4.92 0.4 2.68e-6 Cancer; TGCT cis rs1971762 0.545 rs3864905 chr12:54058324 C/T cg16917193 chr12:54089295 NA 1.07 11.12 0.71 2.39e-20 Height; TGCT cis rs6582630 0.555 rs7305352 chr12:38473800 T/C cg26384229 chr12:38710491 ALG10B 0.88 8.04 0.59 5.98e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs2663905 0.611 rs1509558 chr15:81391244 C/T cg18028999 chr15:81426610 C15orf26 -0.51 -4.68 -0.39 7.24e-6 QT interval (drug interaction); TGCT cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg18654377 chr3:49208889 KLHDC8B -0.45 -5.89 -0.47 3.44e-8 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9372498 0.505 rs62422247 chr6:118987559 G/T cg21191810 chr6:118973309 C6orf204 -0.37 -4.71 -0.39 6.4e-6 Diastolic blood pressure; TGCT cis rs4409675 0.576 rs6565 chr1:28213157 T/C cg23691781 chr1:28212827 C1orf38 0.26 5.32 0.43 4.68e-7 Corneal astigmatism; TGCT cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs2243480 1.000 rs59794892 chr7:65415873 G/A cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs9372498 0.536 rs9489409 chr6:118802721 A/G cg07617317 chr6:118971624 C6orf204 0.51 5.52 0.44 1.92e-7 Diastolic blood pressure; TGCT cis rs9457247 1.000 rs2757042 chr6:167371234 A/T cg23791538 chr6:167370224 RNASET2 0.53 4.97 0.41 2.14e-6 Crohn's disease; TGCT cis rs17331151 0.573 rs3755801 chr3:52865798 G/A cg11137980 chr3:52469226 SEMA3G 0.28 5.07 0.41 1.42e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8072100 0.875 rs12451409 chr17:45544856 A/G cg08085267 chr17:45401833 C17orf57 -0.43 -4.68 -0.39 7.26e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9952991 0.656 rs7235964 chr18:12761249 G/A cg23598886 chr18:12777645 NA -0.65 -4.66 -0.39 8.08e-6 Inflammatory skin disease; TGCT cis rs9394438 0.628 rs4714078 chr6:37543852 G/A cg00985040 chr6:37553208 NA -0.25 -4.97 -0.41 2.19e-6 IgG glycosylation; TGCT cis rs4819052 0.851 rs2838867 chr21:46713092 C/T cg06618935 chr21:46677482 NA -0.36 -5.5 -0.44 2.06e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs873917 0.620 rs784595 chr1:40135017 C/T cg06209491 chr1:40138402 NT5C1A -0.34 -5.9 -0.47 3.29e-8 Amyotrophic lateral sclerosis; TGCT cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2836974 0.565 rs2836939 chr21:40578546 C/T cg17971929 chr21:40555470 PSMG1 0.66 4.63 0.38 8.99e-6 Cognitive function; TGCT cis rs526231 0.853 rs2561477 chr5:102608924 G/A cg05225461 chr5:102596755 C5orf30 0.23 4.65 0.39 8.39e-6 Primary biliary cholangitis; TGCT cis rs10507380 0.824 rs9512638 chr13:27920657 T/C cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs7246657 0.722 rs4802029 chr19:38055612 A/T cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs6542838 0.703 rs7593332 chr2:99467991 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -4.67 -0.39 7.71e-6 Fear of minor pain; TGCT cis rs7772486 0.727 rs11155442 chr6:146140725 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.8 0.66 3.89e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6582630 0.547 rs1589388 chr12:38416025 C/T cg26384229 chr12:38710491 ALG10B -0.53 -4.64 -0.38 8.67e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9653442 0.900 rs6754937 chr2:100827720 T/G cg22139774 chr2:100720529 AFF3 -0.4 -6.34 -0.49 3.95e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10833905 0.680 rs2433479 chr11:23034703 G/A cg06387204 chr11:22647648 FANCF 0.51 4.56 0.38 1.19e-5 Sudden cardiac arrest; TGCT cis rs9549367 0.713 rs9549691 chr13:113861606 A/C cg00898013 chr13:113819073 PROZ -0.52 -6.6 -0.51 1.06e-9 Platelet distribution width; TGCT cis rs2580764 0.565 rs6760429 chr2:55228499 C/T cg09592903 chr2:55203963 RTN4 -0.25 -5.45 -0.44 2.58e-7 Mean platelet volume; TGCT cis rs7647973 0.925 rs9834003 chr3:49216472 T/C cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.79 -0.4 4.63e-6 Menarche (age at onset); TGCT trans rs9650657 0.538 rs6984496 chr8:10796093 G/T cg15556689 chr8:8085844 FLJ10661 -0.79 -6.99 -0.53 1.53e-10 Neuroticism; TGCT cis rs1475911 1.000 rs17114359 chr21:43510437 A/C cg14562523 chr21:43528734 C21orf128;UMODL1 -0.24 -4.9 -0.4 2.94e-6 IgG glycosylation; TGCT cis rs11681930 0.708 rs10165609 chr2:206090248 A/G cg11793701 chr2:206547163 NRP2 0.85 4.45 0.37 1.87e-5 Attention deficit hyperactivity disorder (combined symptoms); TGCT cis rs6500602 0.702 rs4786511 chr16:4571645 C/T cg08645402 chr16:4508243 NA 0.19 5.25 0.43 6.32e-7 Schizophrenia; TGCT cis rs77633900 0.614 rs2629021 chr15:76974083 C/T cg21673338 chr15:77095150 SCAPER -0.5 -4.92 -0.4 2.68e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs7666738 0.830 rs10470894 chr4:99039107 G/A cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs5001324 chr6:8451604 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs17739167 0.550 rs6493014 chr15:42225008 A/G cg20935245 chr15:42234343 EHD4 -0.2 -4.45 -0.37 1.9e-5 Monocyte count; TGCT cis rs79387448 0.638 rs116055209 chr2:103032189 C/T cg09003973 chr2:102972529 NA 1.27 9.82 0.66 3.37e-17 Gut microbiota (bacterial taxa); TGCT cis rs6534347 0.573 rs6814458 chr4:123520842 G/A cg10583651 chr4:123538969 IL21 -0.36 -5.27 -0.43 5.97e-7 Type 1 diabetes; TGCT cis rs709400 0.526 rs8017780 chr14:103987305 C/A cg12935359 chr14:103987150 CKB -0.48 -6.22 -0.49 6.85e-9 Body mass index; TGCT cis rs8017423 0.904 rs7147212 chr14:90697809 A/C cg04374321 chr14:90722782 PSMC1 0.77 8.04 0.59 5.94e-13 Mortality in heart failure; TGCT cis rs1799949 1.000 rs35070007 chr17:41316747 C/G cg05368731 chr17:41323189 NBR1 -1.07 -12.19 -0.74 5.97e-23 Menopause (age at onset); TGCT trans rs2727020 0.755 rs652655 chr11:49251293 G/A cg03929089 chr4:120376271 NA 0.73 8.5 0.61 5.16e-14 Coronary artery disease; TGCT cis rs7208859 0.623 rs9895785 chr17:29107708 C/T cg14008862 chr17:28927542 LRRC37B2 -0.76 -4.44 -0.37 1.93e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9831754 0.906 rs2314196 chr3:78411050 C/T cg06138941 chr3:78371609 NA -0.44 -5.06 -0.41 1.46e-6 Calcium levels; TGCT cis rs3096299 0.658 rs12443705 chr16:89547054 C/G cg02187348 chr16:89574699 SPG7 0.63 6.73 0.52 5.51e-10 Multiple myeloma (IgH translocation); TGCT cis rs921968 0.678 rs660432 chr2:219432127 C/T cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs57590327 0.679 rs13082609 chr3:81642131 A/G cg07356753 chr3:81810745 GBE1 -0.56 -4.64 -0.38 8.77e-6 Extraversion; TGCT cis rs617219 0.698 rs72764983 chr5:78513806 T/C cg23514016 chr5:78407564 BHMT 0.34 5.2 0.42 7.9e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs921968 0.643 rs62191565 chr2:219482017 C/T cg02176678 chr2:219576539 TTLL4 0.45 6.5 0.5 1.79e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs6089829 0.888 rs6011559 chr20:61675620 C/T cg03213289 chr20:61660250 NA -0.68 -8.39 -0.6 8.97e-14 Prostate cancer (SNP x SNP interaction); TGCT trans rs4332037 0.802 rs73048106 chr7:1929019 G/T cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs73201462 1.000 rs2811416 chr3:127991938 A/G cg06138505 chr3:127317209 MCM2 -0.88 -4.56 -0.38 1.2e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7830933 0.822 rs13249197 chr8:23578404 G/T cg04349084 chr8:23602677 NA 0.23 4.44 0.37 1.98e-5 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 1.02 7.55 0.56 8.3e-12 Platelet count; TGCT cis rs875971 1.000 rs55962648 chr7:65625751 C/G cg11764359 chr7:65958608 NA -0.6 -5.32 -0.43 4.63e-7 Aortic root size; TGCT cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg03161606 chr19:29218774 NA 0.6 5.84 0.46 4.28e-8 Methadone dose in opioid dependence; TGCT cis rs593982 0.920 rs1151500 chr11:65481166 T/C cg08755490 chr11:65554678 OVOL1 1.35 8.22 0.59 2.34e-13 Atopic dermatitis; TGCT trans rs853410 0.516 rs6939049 chr6:4009723 G/A cg13911294 chr9:88951310 ZCCHC6 -0.64 -6.66 -0.51 8.02e-10 Night sleep phenotypes; TGCT cis rs73198271 0.523 rs11787172 chr8:8538201 G/A ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.2 -0.42 7.83e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs8177179 0.666 rs4075352 chr3:133468012 A/G cg16414030 chr3:133502952 NA -0.36 -4.86 -0.4 3.5e-6 Iron status biomarkers (transferrin levels); TGCT cis rs4242434 0.927 rs11781149 chr8:22473158 C/T cg03733263 chr8:22462867 KIAA1967 1.15 20.1 0.87 7.99e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9467773 0.967 rs9358954 chr6:26531178 A/G cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.559 rs78267892 chr7:106823734 C/T cg02696742 chr7:106810147 HBP1 -0.72 -6.28 -0.49 5.29e-9 Coronary artery disease; TGCT cis rs2180341 1.000 rs6569480 chr6:127621748 A/G cg27446573 chr6:127587934 RNF146 1.03 9.89 0.66 2.34e-17 Breast cancer; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg25703541 chr22:24373054 LOC391322 -0.89 -10.3 -0.68 2.39e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs709400 0.628 rs1989565 chr14:103862193 G/A cg12935359 chr14:103987150 CKB 0.34 5.2 0.42 7.86e-7 Body mass index; TGCT cis rs10892173 0.566 rs2298649 chr11:117672225 A/G cg04064380 chr11:117688259 NA -0.5 -4.48 -0.37 1.66e-5 Myopia; TGCT cis rs9910055 0.529 rs228757 chr17:42164885 G/C cg19774624 chr17:42201019 HDAC5 0.71 6.35 0.5 3.71e-9 Total body bone mineral density; TGCT cis rs7085104 0.632 rs4290163 chr10:104610926 G/T cg04362960 chr10:104952993 NT5C2 0.56 4.94 0.41 2.49e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs1525293 0.670 rs10269838 chr7:70490427 C/T cg21135135 chr7:70597687 WBSCR17 -0.48 -4.7 -0.39 6.81e-6 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs72647484 1.000 rs72647484 chr1:22587728 T/C cg21876283 chr1:22149684 LDLRAD2;HSPG2 0.27 4.49 0.37 1.6e-5 Colorectal cancer; TGCT trans rs7819412 0.668 rs920047 chr8:11087475 C/T cg15556689 chr8:8085844 FLJ10661 -0.81 -7.89 -0.58 1.38e-12 Triglycerides; TGCT trans rs4650994 1.000 rs10798615 chr1:178513895 T/G cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.33e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs74544699 0.826 rs3756074 chr4:74848065 G/C cg15398841 chr4:74847761 PF4 0.88 4.87 0.4 3.3e-6 Growth-regulated protein alpha levels; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.12e-6 Prudent dietary pattern; TGCT cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs1008375 1.000 rs28501187 chr4:17643620 G/A cg16339924 chr4:17578868 LAP3 0.64 5.47 0.44 2.42e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9910055 0.676 rs11079983 chr17:42198170 C/T cg19774624 chr17:42201019 HDAC5 -0.76 -7.67 -0.57 4.24e-12 Total body bone mineral density; TGCT cis rs763014 0.932 rs34498660 chr16:666149 A/G cg07343612 chr16:622815 PIGQ -0.42 -8.39 -0.6 9.08e-14 Height; TGCT trans rs7864133 1.000 rs11139255 chr9:84064152 A/T cg23451063 chr7:1059876 C7orf50 0.55 6.93 0.53 2.02e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs2204008 0.577 rs11520050 chr12:38051839 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs4919694 1.000 rs17727044 chr10:104821256 A/T cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT cis rs9457247 0.935 rs2757050 chr6:167377165 G/T cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.06e-6 Crohn's disease; TGCT cis rs17102423 0.755 rs11158574 chr14:65579467 T/G cg11161011 chr14:65562177 MAX -0.55 -7.3 -0.55 3.01e-11 Obesity-related traits; TGCT cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg03060546 chr3:49711283 APEH 0.5 4.83 0.4 3.89e-6 Menarche (age at onset); TGCT cis rs7246657 0.943 rs4452075 chr19:37879589 A/G cg18154014 chr19:37997991 ZNF793 0.74 5.33 0.43 4.48e-7 Coronary artery calcification; TGCT cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs10479542 0.896 rs10078712 chr5:178978805 C/T cg19626725 chr5:178986131 RUFY1 -0.45 -5.52 -0.44 1.9e-7 Lung cancer; TGCT cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg12311346 chr5:56204834 C5orf35 -0.67 -6.68 -0.51 7.25e-10 Initial pursuit acceleration; TGCT cis rs7226408 1.000 rs485935 chr18:34370503 C/A cg06757138 chr18:34340585 FHOD3 0.28 4.76 0.39 5.23e-6 Obesity-related traits; TGCT cis rs4713118 0.586 rs6905522 chr6:28086479 A/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Parkinson's disease; TGCT cis rs10751667 0.666 rs7396677 chr11:958878 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.23 -0.59 2.17e-13 Alzheimer's disease (late onset); TGCT cis rs1878931 0.501 rs9302871 chr16:3415512 T/C cg05754148 chr16:3507555 NAT15 -0.33 -4.46 -0.37 1.82e-5 Body mass index (adult); TGCT trans rs34421088 0.560 rs2248699 chr8:11393764 A/G cg15556689 chr8:8085844 FLJ10661 -0.78 -7.43 -0.56 1.56e-11 Neuroticism; TGCT cis rs17826219 0.568 rs9903854 chr17:29153998 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.06 0.41 1.5e-6 Body mass index; TGCT cis rs9581857 0.685 rs9581856 chr13:28025615 G/C cg22138327 chr13:27999177 GTF3A 0.76 5.41 0.44 3.1e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT trans rs561341 0.941 rs550213 chr17:30317518 C/G cg20587970 chr11:113659929 NA -1.05 -12.74 -0.75 2.84e-24 Hip circumference adjusted for BMI; TGCT trans rs7618501 0.601 rs2624825 chr3:50154989 G/A cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.600 rs2895202 chr7:2131829 T/C cg22963979 chr7:1858916 MAD1L1 -0.38 -5.99 -0.47 2.12e-8 Bipolar disorder and schizophrenia; TGCT cis rs12908161 1.000 rs4643294 chr15:85250253 C/T cg11189052 chr15:85197271 WDR73 0.75 6.29 0.49 5.02e-9 Schizophrenia; TGCT cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg15659132 chr6:26577336 NA 0.84 10.39 0.68 1.39e-18 Intelligence (multi-trait analysis); TGCT cis rs1801251 0.963 rs35362030 chr2:233612845 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.52 0.51 1.58e-9 Coronary artery disease; TGCT cis rs12477438 0.501 rs13033012 chr2:99795149 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs16958440 0.867 rs9304342 chr18:44720199 T/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs9457247 1.000 rs407515 chr6:167407544 G/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs10504229 0.683 rs58883273 chr8:58138275 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT cis rs748404 0.631 rs7166812 chr15:43644760 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg21724239 chr8:58056113 NA 0.39 5.29 0.43 5.44e-7 Developmental language disorder (linguistic errors); TGCT cis rs2288278 0.601 rs11079825 chr17:46596312 C/T cg25032089 chr17:46643351 HOXB3 -0.42 -5.01 -0.41 1.86e-6 Hand grip strength; TGCT cis rs838147 0.508 rs507766 chr19:49208543 T/C cg13540341 chr19:49222985 MAMSTR -0.38 -4.93 -0.4 2.61e-6 Dietary macronutrient intake; TGCT cis rs6906287 0.647 rs12211576 chr6:118872080 G/A cg21191810 chr6:118973309 C6orf204 0.26 4.5 0.38 1.51e-5 Electrocardiographic conduction measures; TGCT cis rs11098499 0.530 rs114866537 chr4:120258608 A/T cg09307838 chr4:120376055 NA 0.55 5.29 0.43 5.31e-7 Corneal astigmatism; TGCT trans rs7819412 0.775 rs4545055 chr8:10935366 T/C cg15556689 chr8:8085844 FLJ10661 -0.84 -8.16 -0.59 3.12e-13 Triglycerides; TGCT cis rs208520 0.739 rs1935894 chr6:66891434 A/G cg07460842 chr6:66804631 NA -0.9 -9.33 -0.64 5.29e-16 Exhaled nitric oxide output; TGCT cis rs6912958 0.781 rs6454631 chr6:88225863 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.99 -0.41 2.03e-6 Monocyte percentage of white cells; TGCT cis rs889312 0.521 rs12651942 chr5:56088484 C/T cg24531977 chr5:56204891 C5orf35 -0.48 -4.92 -0.4 2.64e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs7772486 0.558 rs702322 chr6:146007166 G/A cg23711669 chr6:146136114 FBXO30 -0.73 -6.84 -0.52 3.19e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs644799 0.932 rs572015 chr11:95637416 T/A cg03916912 chr11:95522834 CEP57;FAM76B 0.84 9.92 0.67 1.94e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg18402987 chr7:1209562 NA 0.67 5.93 0.47 2.87e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11679640 0.836 rs17682575 chr2:43152304 C/T cg18281102 chr2:44065550 ABCG5;ABCG8 -0.26 -4.62 -0.38 9.58e-6 White matter hyperintensity burden; TGCT cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg06108461 chr20:60628389 TAF4 -0.75 -11.03 -0.7 3.95e-20 Body mass index; TGCT cis rs151997 0.893 rs27607 chr5:50228977 A/G cg06027927 chr5:50259733 NA -0.46 -4.6 -0.38 1.03e-5 Callous-unemotional behaviour; TGCT cis rs6089829 0.851 rs4809460 chr20:61661355 T/C cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs769267 0.965 rs2074303 chr19:19381755 C/T cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs8056742 0.730 rs116531971 chr16:85072347 T/C cg00229868 chr16:85520891 NA 0.4 5.18 0.42 8.9e-7 Amyotrophic lateral sclerosis; TGCT cis rs10501293 0.584 rs7120544 chr11:43040945 T/C cg03447554 chr11:43094025 NA 0.33 4.5 0.37 1.53e-5 Cognitive performance; TGCT cis rs877282 0.898 rs12356709 chr10:763365 A/G cg17470449 chr10:769945 NA 0.36 5.17 0.42 9.01e-7 Uric acid levels; TGCT cis rs4819052 0.851 rs9974628 chr21:46672647 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7267979 0.753 rs404148 chr20:25447931 A/G cg03522245 chr20:25566470 NINL 0.52 5.2 0.42 8.01e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3924048 0.559 rs6541038 chr1:12626210 G/T cg00291366 chr1:12616550 NA 0.32 5.01 0.41 1.86e-6 Optic cup area; TGCT cis rs6750795 0.870 rs6754952 chr2:232381245 G/T cg19187155 chr2:232395269 NMUR1 -0.53 -6.3 -0.49 4.78e-9 Height; TGCT cis rs7611238 0.560 rs60100329 chr3:195078662 A/C cg27323046 chr3:195102265 ACAP2 0.37 4.93 0.4 2.56e-6 Body mass index; TGCT cis rs860554 0.595 rs12025174 chr1:201258309 G/A cg01022117 chr1:201258280 PKP1 -0.35 -6.85 -0.52 3.1e-10 Panic disorder; TGCT cis rs477895 0.713 rs12575642 chr11:63979643 G/T cg23719950 chr11:63933701 MACROD1 -0.72 -6.16 -0.48 9.41e-9 Mean platelet volume; TGCT cis rs2836974 0.831 rs34592564 chr21:40516288 G/C cg06238570 chr21:40685208 BRWD1 0.58 5.11 0.42 1.16e-6 Cognitive function; TGCT cis rs9549367 0.713 rs576463 chr13:113846614 C/T cg09473364 chr13:112927190 NA 0.29 4.64 0.38 8.73e-6 Platelet distribution width; TGCT cis rs12681287 0.640 rs7820234 chr8:87350950 A/C cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs5821446 1 rs5821446 chr17:65962538 A/AT cg12091567 chr17:66097778 LOC651250 0.81 6.14 0.48 1.02e-8 Eosinophil percentage of granulocytes; TGCT cis rs11997175 0.574 rs4370495 chr8:33654819 G/A ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs3020736 0.500 rs6002623 chr22:42513761 G/A cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs977747 0.872 rs6695898 chr1:47681761 G/A cg03885399 chr1:47691550 TAL1 -0.43 -5.44 -0.44 2.72e-7 Body mass index; TGCT cis rs17221829 0.645 rs12288897 chr11:89388816 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs4938573 0.526 rs11216973 chr11:118587001 T/C cg19308663 chr11:118741387 NA 0.25 4.48 0.37 1.66e-5 Follicular lymphoma; TGCT cis rs12967678 1 rs12967678 chr18:12805388 G/A cg23544223 chr18:12777786 NA -0.66 -5.33 -0.43 4.42e-7 Selective IgA deficiency; TGCT cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9467773 0.626 rs6936006 chr6:26350565 A/G cg05738196 chr6:26577821 NA -0.63 -6.77 -0.52 4.5e-10 Intelligence (multi-trait analysis); TGCT cis rs7819412 0.642 rs11250117 chr8:10972740 C/A cg12940923 chr8:10282607 MSRA -0.19 -4.6 -0.38 1.05e-5 Triglycerides; TGCT cis rs981844 0.712 rs1456397 chr4:154744554 C/G cg14289246 chr4:154710475 SFRP2 1.0 9.35 0.64 4.84e-16 Response to statins (LDL cholesterol change); TGCT cis rs10751667 0.643 rs12278229 chr11:946985 A/G cg06064525 chr11:970664 AP2A2 -0.36 -8.24 -0.59 2.11e-13 Alzheimer's disease (late onset); TGCT cis rs7666738 0.830 rs28818218 chr4:98880575 A/C cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13223928 0.605 rs10951052 chr7:3155301 A/G cg19214707 chr7:3157722 NA -0.45 -6.06 -0.48 1.54e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg07157834 chr1:205819609 PM20D1 0.45 7.32 0.55 2.76e-11 Menarche (age at onset); TGCT cis rs7647973 0.710 rs12637313 chr3:49645458 A/G cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs7937682 0.632 rs11214037 chr11:111773296 C/T cg09085632 chr11:111637200 PPP2R1B 0.84 7.33 0.55 2.55e-11 Primary sclerosing cholangitis; TGCT cis rs1018836 0.798 rs4735295 chr8:91671608 C/A cg16814680 chr8:91681699 NA -0.97 -12.22 -0.74 5.02e-23 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs17384381 1.000 rs12132677 chr1:85879613 A/C cg16011679 chr1:85725395 C1orf52 0.8 6.44 0.5 2.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4595586 0.525 rs12809307 chr12:39365927 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2180341 0.960 rs7745944 chr6:127709574 A/G cg27446573 chr6:127587934 RNF146 1.16 10.47 0.68 9.13e-19 Breast cancer; TGCT cis rs763014 1.000 rs2269558 chr16:682250 C/T cg07343612 chr16:622815 PIGQ -0.42 -8.53 -0.61 4.32e-14 Height; TGCT cis rs4523957 0.614 rs7217108 chr17:2059408 G/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs208520 0.955 rs17644076 chr6:67004973 A/G cg07460842 chr6:66804631 NA -0.68 -5.96 -0.47 2.41e-8 Exhaled nitric oxide output; TGCT cis rs2549003 1.000 rs6873426 chr5:131818631 G/T cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs1218582 0.741 rs11264291 chr1:154914797 C/T cg24250549 chr1:154909240 PMVK 0.63 6.45 0.5 2.25e-9 Prostate cancer; TGCT cis rs17122693 0.748 rs57198801 chr14:51119456 T/C cg04730355 chr14:51134070 SAV1 1.35 12.44 0.75 1.47e-23 Cognitive performance; TGCT cis rs17376456 0.877 rs17315943 chr5:93442830 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs7917772 0.582 rs7087984 chr10:104380686 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.56 5.47 0.44 2.35e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs727505 1.000 rs66922607 chr7:124512555 T/A cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs10197940 0.710 rs4500942 chr2:152334580 A/G cg06191203 chr2:152266755 RIF1 -0.8 -7.89 -0.58 1.39e-12 Lung cancer; TGCT cis rs7523050 0.643 rs12729998 chr1:109405505 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs9814567 0.929 rs9838834 chr3:134207077 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -9.27 -0.64 7.51e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4808199 0.895 rs12981405 chr19:19651577 C/T cg03709012 chr19:19516395 GATAD2A 0.98 6.87 0.52 2.78e-10 Nonalcoholic fatty liver disease; TGCT cis rs6951245 0.529 rs76001997 chr7:1152615 C/T cg03188948 chr7:1209495 NA 0.5 5.23 0.43 6.99e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg07092213 chr7:1199455 ZFAND2A -0.51 -5.57 -0.45 1.5e-7 Longevity;Endometriosis; TGCT cis rs611744 0.967 rs2600615 chr8:109201170 G/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs7570971 0.617 rs1869829 chr2:135877562 C/T cg07169764 chr2:136633963 MCM6 -0.62 -4.86 -0.4 3.41e-6 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs853679 0.517 rs1904840 chr6:28108232 C/T cg12963246 chr6:28129442 ZNF389 0.53 5.09 0.42 1.27e-6 Depression; TGCT cis rs6570726 0.791 rs1280275 chr6:145892402 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7831492 0.564 rs6981979 chr8:41612255 C/T cg17182837 chr8:41585554 ANK1 -0.17 -4.52 -0.38 1.44e-5 Colorectal cancer; TGCT cis rs71597109 0.568 rs11940244 chr4:102727575 G/T cg14855874 chr4:102712397 BANK1 0.41 4.72 0.39 6.16e-6 Chronic lymphocytic leukemia; TGCT cis rs3821902 0.547 rs56237630 chr3:64049375 C/A cg22134162 chr3:63841271 THOC7 -0.33 -4.91 -0.4 2.82e-6 Breast cancer; TGCT cis rs7666738 0.830 rs34892904 chr4:98938097 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9814567 0.712 rs9838119 chr3:134331980 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4523957 0.583 rs6503302 chr17:2052704 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.69e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9372253 1.000 rs9384740 chr6:110716207 G/A cg01119278 chr6:110721349 DDO -0.35 -5.68 -0.45 9e-8 Platelet distribution width; TGCT cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg21724239 chr8:58056113 NA 0.39 5.29 0.43 5.33e-7 Developmental language disorder (linguistic errors); TGCT cis rs7547997 0.517 rs6687405 chr1:158240757 T/G cg03528325 chr1:158223921 CD1A 0.34 4.58 0.38 1.11e-5 QRS duration; TGCT cis rs17001868 0.568 rs3788579 chr22:40742989 T/C cg07138101 chr22:40742427 ADSL 0.72 5.25 0.43 6.46e-7 Mammographic density (dense area); TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg08859206 chr1:53392774 SCP2 -0.42 -6.4 -0.5 2.95e-9 Monocyte count; TGCT cis rs10493773 0.609 rs12058974 chr1:86192235 T/A cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs9359856 0.636 rs9294440 chr6:90308666 C/G cg13799429 chr6:90582589 CASP8AP2 0.45 4.61 0.38 9.8e-6 Bipolar disorder; TGCT cis rs644799 0.601 rs662168 chr11:95586982 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.69 7.18 0.54 5.72e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12765878 1.000 rs12765878 chr10:105669622 C/T cg11005552 chr10:105648138 OBFC1 -0.44 -7.7 -0.57 3.69e-12 Coronary artery disease; TGCT cis rs2115630 0.905 rs6496401 chr15:85297793 A/T cg12501888 chr15:85177176 SCAND2 -0.48 -4.49 -0.37 1.6e-5 P wave terminal force; TGCT cis rs7584330 0.737 rs7568588 chr2:238364342 G/T cg14458575 chr2:238380390 NA 0.51 8.14 0.59 3.53e-13 Prostate cancer; TGCT cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -6.02 -0.48 1.8e-8 Alzheimer's disease; TGCT cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs617219 0.853 rs57587638 chr5:78513167 C/T cg09550809 chr5:78407562 BHMT 0.35 4.56 0.38 1.22e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs514406 0.505 rs6688064 chr1:53165609 C/T cg16325326 chr1:53192061 ZYG11B 0.85 11.53 0.72 2.38e-21 Monocyte count; TGCT cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg03806693 chr22:41940476 POLR3H -1.13 -12.67 -0.75 4.12e-24 Vitiligo; TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg09177884 chr7:1199841 ZFAND2A -0.63 -6.58 -0.51 1.2e-9 Longevity;Endometriosis; TGCT cis rs10501293 1.000 rs12222341 chr11:43126722 T/G cg03447554 chr11:43094025 NA -0.49 -6.9 -0.53 2.33e-10 Cognitive performance; TGCT cis rs6089584 0.888 rs6089623 chr20:60615759 A/G cg06108461 chr20:60628389 TAF4 -0.69 -10.77 -0.7 1.71e-19 Body mass index; TGCT cis rs7611238 0.560 rs11718226 chr3:195054345 C/A cg27323046 chr3:195102265 ACAP2 0.35 4.75 0.39 5.5e-6 Body mass index; TGCT cis rs1691799 0.867 rs1168338 chr12:66759369 T/C cg16791601 chr12:66731901 HELB -0.29 -6.18 -0.49 8.39e-9 White blood cell count (basophil); TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg09177884 chr7:1199841 ZFAND2A -0.63 -6.61 -0.51 1.01e-9 Longevity;Endometriosis; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg25767906 chr1:53392781 SCP2 -0.55 -6.3 -0.49 4.75e-9 Monocyte count; TGCT cis rs797680 0.856 rs1335679 chr1:93645182 C/T cg17826107 chr1:92977322 EVI5 -0.24 -5.27 -0.43 5.93e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9653442 0.648 rs6733895 chr2:100666082 C/G cg07810366 chr2:100720526 AFF3 -0.42 -7.18 -0.54 5.78e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6964587 0.610 rs6465338 chr7:91450624 T/C cg17063962 chr7:91808500 NA 0.73 6.69 0.52 6.75e-10 Breast cancer; TGCT cis rs7731657 0.537 rs3981333 chr5:130375045 A/T cg08523029 chr5:130500466 HINT1 -0.64 -5.33 -0.43 4.38e-7 Fasting plasma glucose; TGCT cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Intelligence (multi-trait analysis); TGCT cis rs877282 0.898 rs11253339 chr10:759640 C/T cg17470449 chr10:769945 NA 0.36 5.35 0.43 4.04e-7 Uric acid levels; TGCT cis rs9942416 0.660 rs4704234 chr5:75001432 A/G cg00601450 chr5:74908170 NA 0.38 4.65 0.39 8.34e-6 Age-related disease endophenotypes; TGCT cis rs3087591 0.801 rs2012535 chr17:29561391 A/T cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.68 -0.57 4.06e-12 Hip circumference; TGCT cis rs36051895 0.623 rs4358852 chr9:5251238 C/T cg02405213 chr9:5042618 JAK2 -0.73 -9.79 -0.66 4.1e-17 Pediatric autoimmune diseases; TGCT cis rs2692947 0.696 rs2576437 chr2:96800417 T/C cg22654517 chr2:96458247 NA 0.22 4.83 0.4 4e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4927850 0.723 rs7630825 chr3:195753740 T/C cg12923728 chr3:195709715 SDHAP1 -0.37 -7.3 -0.55 3.07e-11 Pancreatic cancer; TGCT cis rs4253772 0.513 rs9306512 chr22:46716603 T/C cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 5.14 0.42 1.02e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs1577917 0.710 rs1059306 chr6:86388109 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 5.58 0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs3806843 0.546 rs246023 chr5:140333990 G/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs55823223 0.564 rs9894009 chr17:73850414 C/T cg08125733 chr17:73851984 WBP2 0.87 8.8 0.62 1e-14 Psoriasis; TGCT cis rs9916302 0.706 rs11657153 chr17:37699729 A/G cg03321784 chr17:37729644 NA 0.44 4.58 0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg23156509 chr2:114033830 PAX8;LOC440839 -0.31 -4.83 -0.4 3.92e-6 Lymphocyte counts; TGCT cis rs28595532 0.920 rs116023902 chr4:119725131 A/G cg14228332 chr4:119757509 SEC24D 1.38 6.93 0.53 2.07e-10 Cannabis dependence symptom count; TGCT cis rs6061231 1.000 rs67941642 chr20:60958108 C/T cg24112000 chr20:60950667 NA -0.36 -5.23 -0.42 7.05e-7 Colorectal cancer; TGCT cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg26118208 chr10:134322334 NA 0.26 5.0 0.41 1.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs763014 0.865 rs8909 chr16:633851 T/C cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs28374715 0.578 rs8036026 chr15:41630499 C/G cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.93 -0.8 1.76e-29 Ulcerative colitis; TGCT cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg12756686 chr19:29218302 NA 0.76 6.49 0.5 1.85e-9 Methadone dose in opioid dependence; TGCT cis rs17125944 0.556 rs7152229 chr14:53313405 T/C cg00686598 chr14:53173677 PSMC6 -0.86 -4.71 -0.39 6.42e-6 Alzheimer's disease (late onset); TGCT cis rs7178424 0.806 rs4775453 chr15:62217391 A/C cg00456672 chr15:62358751 C2CD4A 0.31 4.73 0.39 6.09e-6 Height; TGCT cis rs7666738 0.830 rs34461023 chr4:99023751 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.62 0.56 5.53e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1691799 0.867 rs2172881 chr12:66766039 C/G cg16791601 chr12:66731901 HELB -0.28 -6.01 -0.47 1.94e-8 White blood cell count (basophil); TGCT cis rs2075371 0.527 rs1862046 chr7:134023524 T/C cg11752832 chr7:134001865 SLC35B4 0.67 5.47 0.44 2.34e-7 Mean platelet volume; TGCT cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg05665937 chr4:1216051 CTBP1 0.25 4.68 0.39 7.33e-6 Obesity-related traits; TGCT cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg26531700 chr6:26746687 NA 0.53 5.04 0.41 1.58e-6 Intelligence (multi-trait analysis); TGCT cis rs7611238 0.538 rs13316914 chr3:195153124 C/T cg27323046 chr3:195102265 ACAP2 0.39 5.14 0.42 1.05e-6 Body mass index; TGCT cis rs9311474 0.597 rs13303 chr3:52558008 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.53 5.07 0.41 1.42e-6 Electroencephalogram traits; TGCT cis rs9916302 0.904 rs8076546 chr17:37555403 G/A cg07936489 chr17:37558343 FBXL20 0.65 4.98 0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs4886920 0.563 rs8039011 chr15:78078445 A/G cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs6988636 1.000 rs16898088 chr8:124190501 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs2857078 1.000 rs2857078 chr17:42330171 A/C cg19774624 chr17:42201019 HDAC5 0.62 5.7 0.46 8.17e-8 Red cell distribution width;Reticulocyte count; TGCT cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg11502198 chr6:26597334 ABT1 0.52 4.64 0.38 8.69e-6 Intelligence (multi-trait analysis); TGCT cis rs2239547 0.563 rs4302374 chr3:52905802 T/C cg10802521 chr3:52805072 NEK4 -0.58 -5.46 -0.44 2.53e-7 Schizophrenia; TGCT cis rs3806843 0.735 rs801167 chr5:140081423 A/G cg19875535 chr5:140030758 IK 0.36 6.09 0.48 1.31e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7804356 1.000 rs73065517 chr7:26830555 T/C cg03456212 chr7:26904342 SKAP2 -0.63 -4.88 -0.4 3.19e-6 Type 1 diabetes; TGCT cis rs932287 0.540 rs4910442 chr11:9044337 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.8 0.4 4.55e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12220238 1.000 rs10762582 chr10:75968316 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2836950 0.545 rs2836922 chr21:40516308 C/T cg17971929 chr21:40555470 PSMG1 -0.54 -4.98 -0.41 2.06e-6 Menarche (age at onset); TGCT cis rs6429082 0.713 rs867363 chr1:235579727 A/G cg26050004 chr1:235667680 B3GALNT2 -0.57 -5.03 -0.41 1.7e-6 Adiposity; TGCT cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg15659132 chr6:26577336 NA -0.81 -10.32 -0.68 2.15e-18 Intelligence (multi-trait analysis); TGCT cis rs9325144 0.555 rs4882358 chr12:38726640 A/G cg13010199 chr12:38710504 ALG10B 0.52 4.54 0.38 1.32e-5 Morning vs. evening chronotype; TGCT cis rs6882046 0.513 rs628158 chr5:88041781 G/A cg22951263 chr5:87985283 NA -0.55 -5.91 -0.47 3.09e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs28595532 0.841 rs116452272 chr4:119770802 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs2486288 0.656 rs11854365 chr15:45558083 G/A cg26924012 chr15:45694286 SPATA5L1 -0.75 -7.78 -0.57 2.39e-12 Glomerular filtration rate; TGCT cis rs1941023 0.503 rs4939350 chr11:60136243 C/G cg08716584 chr11:60157161 MS4A7 -0.31 -4.56 -0.38 1.21e-5 Congenital heart disease (maternal effect); TGCT trans rs1814175 0.669 rs10839315 chr11:49654406 G/A cg15704280 chr7:45808275 SEPT13 -0.63 -7.39 -0.55 1.92e-11 Height; TGCT cis rs2688608 0.530 rs71507081 chr10:75493136 G/A cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT trans rs2727020 0.658 rs10839278 chr11:49450847 G/C cg15704280 chr7:45808275 SEPT13 -0.77 -8.75 -0.62 1.29e-14 Coronary artery disease; TGCT cis rs7267979 0.934 rs2261753 chr20:25262291 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2067615 0.524 rs10778498 chr12:107063340 C/A cg15890332 chr12:107067104 RFX4 0.28 5.56 0.45 1.59e-7 Heart rate; TGCT cis rs877282 1.000 rs34257857 chr10:772993 C/A cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs4689592 0.619 rs3796908 chr4:7061378 G/A cg25660036 chr4:7070649 GRPEL1 -0.6 -5.17 -0.42 9.07e-7 Monocyte percentage of white cells; TGCT trans rs8073060 0.586 rs7217533 chr17:34015876 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7246657 0.722 rs4802051 chr19:38072328 C/A cg03611452 chr19:38183253 ZNF781 0.6 4.83 0.4 3.97e-6 Coronary artery calcification; TGCT cis rs7666738 0.830 rs28785514 chr4:98959135 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs66573146 0.831 rs56031152 chr4:6973832 C/A cg07817883 chr1:32538562 TMEM39B 1.42 7.53 0.56 8.92e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs80282103 0.618 rs1079389 chr10:1161980 A/G cg18964960 chr10:1102726 WDR37 1.03 4.55 0.38 1.28e-5 Glomerular filtration rate (creatinine); TGCT cis rs926938 0.521 rs360649 chr1:115439668 G/C cg12756093 chr1:115239321 AMPD1 0.4 6.05 0.48 1.58e-8 Autism; TGCT cis rs12049351 0.613 rs12037690 chr1:229642385 G/A cg12130225 chr1:229698885 NA 0.39 4.6 0.38 1.02e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs861020 0.959 rs658860 chr1:209990549 C/T cg05527609 chr1:210001259 C1orf107 0.91 7.4 0.55 1.84e-11 Orofacial clefts; TGCT cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28374715 0.662 rs13329579 chr15:41467435 C/T cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.41 -0.72 4.6e-21 Ulcerative colitis; TGCT cis rs854765 0.647 rs7406744 chr17:17981938 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.69 7.2 0.54 5.18e-11 Total body bone mineral density; TGCT cis rs137603 1.000 rs137607 chr22:39695505 G/A cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -5.12 -0.42 1.13e-6 Primary biliary cholangitis; TGCT cis rs611744 0.934 rs673356 chr8:109185159 A/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg08219700 chr8:58056026 NA 0.37 4.48 0.37 1.71e-5 Developmental language disorder (linguistic errors); TGCT cis rs35146811 0.731 rs2257213 chr7:99810113 T/C cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs6089584 0.888 rs2146853 chr20:60617908 A/T cg16423285 chr20:60520624 NA -0.61 -6.57 -0.51 1.23e-9 Body mass index; TGCT cis rs539096 0.692 rs6686238 chr1:44210253 C/G cg12908607 chr1:44402522 ARTN -0.63 -7.43 -0.56 1.52e-11 Intelligence (multi-trait analysis); TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg08736216 chr1:53307985 ZYG11A -0.29 -5.99 -0.47 2.1e-8 Monocyte count; TGCT cis rs916888 0.610 rs199438 chr17:44791643 G/A cg17911788 chr17:44343683 NA -0.48 -5.64 -0.45 1.08e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1059312 0.808 rs4760533 chr12:129297651 A/G cg09035930 chr12:129282057 SLC15A4 -0.55 -10.97 -0.7 5.38e-20 Systemic lupus erythematosus; TGCT cis rs12681287 0.752 rs10103229 chr8:87248954 C/T cg27223183 chr8:87520930 FAM82B 0.81 5.64 0.45 1.09e-7 Caudate activity during reward; TGCT cis rs42648 0.642 rs11771963 chr7:89887587 G/T cg25739043 chr7:89950458 NA -0.54 -5.04 -0.41 1.62e-6 Homocysteine levels; TGCT cis rs1801251 1.000 rs11679079 chr2:233612656 C/T cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs2070488 0.804 rs13100195 chr3:38482539 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.96 0.58 9.56e-13 Electrocardiographic conduction measures; TGCT cis rs9372253 0.678 rs9487392 chr6:110708626 C/T cg19196401 chr6:110721138 DDO 0.43 5.92 0.47 2.99e-8 Platelet distribution width; TGCT cis rs12950390 0.853 rs10445375 chr17:45864314 C/T cg24803719 chr17:45855879 NA 0.49 5.03 0.41 1.64e-6 IgG glycosylation; TGCT cis rs28595532 0.764 rs56071514 chr4:119761833 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9467711 0.516 rs1324087 chr6:25841408 A/G cg12310025 chr6:25882481 NA 0.72 4.77 0.39 5.17e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs3806843 0.547 rs246065 chr5:140323638 A/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6558174 0.930 rs12676084 chr8:22493350 C/T cg03733263 chr8:22462867 KIAA1967 0.65 5.19 0.42 8.19e-7 Breast cancer; TGCT cis rs13191362 0.507 rs2849511 chr6:163139050 C/G cg21926612 chr6:163149169 PACRG;PARK2 -0.6 -5.42 -0.44 3.04e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9393692 0.905 rs1124999 chr6:26287043 G/T cg05868516 chr6:26286170 HIST1H4H 0.63 5.9 0.47 3.18e-8 Educational attainment; TGCT cis rs4299518 1.000 rs4299518 chr3:45809273 C/T cg04837898 chr3:45731254 SACM1L 0.45 4.59 0.38 1.05e-5 Hirschsprung disease; TGCT cis rs4237845 0.816 rs61935769 chr12:58294344 G/A cg23860436 chr12:58378763 NA 0.37 5.12 0.42 1.12e-6 Intelligence (multi-trait analysis); TGCT cis rs6089584 1.000 rs6089583 chr20:60563624 G/A cg16423285 chr20:60520624 NA -0.52 -5.45 -0.44 2.6e-7 Body mass index; TGCT cis rs7666738 0.830 rs28887893 chr4:98963006 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10791097 0.690 rs12284487 chr11:130729705 T/C cg05962950 chr11:130786565 SNX19 0.81 9.74 0.66 5.3e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs28595532 1.000 rs56000725 chr4:119637675 G/A cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs10931896 0.531 rs295117 chr2:201146828 C/T cg17644776 chr2:200775616 C2orf69 0.26 4.72 0.39 6.19e-6 Systolic blood pressure; TGCT cis rs7666738 0.830 rs6832568 chr4:98994061 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs61884328 0.733 rs77654484 chr11:47206594 C/A cg13308137 chr11:47528955 CUGBP1 0.38 4.48 0.37 1.65e-5 Total body bone mineral density (age over 60); TGCT cis rs2070488 0.804 rs13094715 chr3:38504430 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.85 0.58 1.64e-12 Electrocardiographic conduction measures; TGCT cis rs12497850 0.627 rs4974078 chr3:49009386 C/T cg06212747 chr3:49208901 KLHDC8B 0.52 5.35 0.43 4.01e-7 Parkinson's disease; TGCT cis rs6089829 0.926 rs6062395 chr20:61667904 A/G cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.77e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs1050631 1.000 rs719147 chr18:33698192 T/G cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.98 0.41 2.12e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg23982607 chr1:1823379 GNB1 -0.55 -8.17 -0.59 2.98e-13 Body mass index; TGCT cis rs6933660 0.721 rs2128945 chr6:151767907 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.56 5.3 0.43 5.22e-7 Menarche (age at onset); TGCT cis rs9818758 0.607 rs34343820 chr3:49309534 C/G cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs999943 0.846 rs10947420 chr6:33611061 C/G cg14003231 chr6:33640908 ITPR3 0.39 4.9 0.4 2.97e-6 Obesity (extreme); TGCT trans rs1005277 0.528 rs2057228 chr10:38515766 T/C cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7192750 0.586 rs8057124 chr16:71972409 T/C cg06353428 chr16:71660113 MARVELD3 0.77 6.82 0.52 3.61e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs939658 0.805 rs11634903 chr15:79436192 C/T cg17916960 chr15:79447300 NA 0.53 8.41 0.6 8.3e-14 Refractive error; TGCT cis rs7226408 0.894 rs17652340 chr18:34391103 A/G cg06757138 chr18:34340585 FHOD3 -0.26 -4.72 -0.39 6.24e-6 Obesity-related traits; TGCT cis rs986417 0.748 rs11158289 chr14:61032390 C/T cg27398547 chr14:60952738 C14orf39 1.33 10.37 0.68 1.56e-18 Gut microbiota (bacterial taxa); TGCT cis rs12464483 0.524 rs2602772 chr2:30885263 C/A cg12454169 chr2:30669597 LCLAT1 0.46 5.15 0.42 1.01e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs7944584 0.610 rs2596407 chr11:47361838 A/G cg20307385 chr11:47447363 PSMC3 -0.79 -7.99 -0.58 8.1e-13 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs7666738 0.861 rs13139309 chr4:99020916 A/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.518 rs35093305 chr11:68730729 A/G cg04772025 chr11:68637568 NA 0.61 6.78 0.52 4.36e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs919433 0.617 rs12619333 chr2:198567638 C/G cg00792783 chr2:198669748 PLCL1 -0.55 -5.04 -0.41 1.62e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs10057188 1.000 rs34026188 chr5:77855871 C/A cg06873401 chr5:77792105 LHFPL2 -0.23 -4.62 -0.38 9.39e-6 Pulse pressure; TGCT cis rs61884328 0.777 rs17790342 chr11:47127706 G/A cg13308137 chr11:47528955 CUGBP1 0.35 4.47 0.37 1.75e-5 Total body bone mineral density (age over 60); TGCT cis rs67311347 1.000 rs9854493 chr3:40423622 T/C cg13409248 chr3:40428643 ENTPD3 0.57 4.57 0.38 1.17e-5 Renal cell carcinoma; TGCT cis rs6570726 0.791 rs408443 chr6:145874643 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1997103 1.000 rs4590393 chr7:55408990 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs155076 1.000 rs261406 chr13:21855854 G/A cg14456004 chr13:21872349 NA -1.23 -10.21 -0.68 3.9e-18 White matter hyperintensity burden; TGCT cis rs36051895 0.623 rs10975033 chr9:5262567 C/T cg02405213 chr9:5042618 JAK2 -0.64 -8.14 -0.59 3.49e-13 Pediatric autoimmune diseases; TGCT cis rs1056053 0.514 rs3127334 chr6:166574246 G/A cg17219086 chr6:166541254 NA -0.19 -4.5 -0.37 1.55e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9653442 0.545 rs11123814 chr2:100767082 A/G cg07810366 chr2:100720526 AFF3 -0.34 -5.13 -0.42 1.1e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3862260 0.509 rs3795662 chr1:120165135 G/T cg11530693 chr1:120165357 ZNF697 0.21 4.75 0.39 5.48e-6 Systemic lupus erythematosus; TGCT cis rs7100689 0.622 rs1890890 chr10:82090643 A/T cg01528321 chr10:82214614 TSPAN14 0.75 7.42 0.55 1.64e-11 Post bronchodilator FEV1; TGCT cis rs9611565 0.592 rs5758405 chr22:42076381 C/A cg13695892 chr22:41940480 POLR3H 0.9 9.02 0.63 2.89e-15 Vitiligo; TGCT cis rs6088590 1.000 rs12626122 chr20:33425800 A/G cg06115741 chr20:33292138 TP53INP2 0.65 5.22 0.42 7.25e-7 Coronary artery disease; TGCT cis rs9611565 0.649 rs9623450 chr22:42175231 G/A cg06634786 chr22:41940651 POLR3H 0.78 7.31 0.55 2.85e-11 Vitiligo; TGCT cis rs319204 0.760 rs319166 chr5:146293197 A/G cg25021259 chr5:146258546 PPP2R2B 0.36 4.66 0.39 8.15e-6 Schizophrenia; TGCT cis rs8192284 1.000 rs2228145 chr1:154426970 A/C cg11650704 chr1:154556575 ADAR 0.25 4.49 0.37 1.58e-5 Fibrinogen;C-reactive protein;Fibrinogen levels; TGCT cis rs9467711 1.000 rs9467701 chr6:26312170 G/C cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs262150 1.000 rs262150 chr7:158777934 G/A cg19418458 chr7:158789849 NA -0.45 -4.62 -0.38 9.5e-6 Facial morphology (factor 20); TGCT cis rs459571 0.959 rs2520100 chr9:136918137 A/T cg13789015 chr9:136890014 NCRNA00094 0.4 7.15 0.54 6.64e-11 Platelet distribution width; TGCT cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg02187348 chr16:89574699 SPG7 0.62 6.72 0.52 5.91e-10 Multiple myeloma (IgH translocation); TGCT cis rs1008375 0.835 rs9760627 chr4:17651508 C/T cg16339924 chr4:17578868 LAP3 0.67 5.52 0.44 1.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11190604 1.000 rs1417823 chr10:102227886 C/T cg16342193 chr10:102329863 NA 0.39 5.14 0.42 1.03e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1218582 0.772 rs4240875 chr1:154885782 G/A cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs2836950 0.565 rs7278297 chr21:40625752 A/C cg11644478 chr21:40555479 PSMG1 -0.51 -4.77 -0.39 5.15e-6 Menarche (age at onset); TGCT cis rs9611565 0.921 rs5751077 chr22:41720728 G/C cg13695892 chr22:41940480 POLR3H -0.72 -7.33 -0.55 2.61e-11 Vitiligo; TGCT cis rs2153535 0.580 rs1115079 chr6:8449615 G/C cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs6738485 0.507 rs66569888 chr2:106886967 G/A cg15412446 chr2:106886593 NA -0.45 -4.79 -0.39 4.75e-6 Pursuit maintenance gain;Pursuit maintenance gain in psychotic disorders; TGCT cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg07507251 chr3:52567010 NT5DC2 0.46 6.34 0.5 3.8e-9 Bipolar disorder; TGCT cis rs2762353 0.935 rs1359232 chr6:25809716 C/A cg03264133 chr6:25882463 NA 0.52 5.38 0.43 3.59e-7 Blood metabolite levels; TGCT cis rs9435341 0.731 rs4914939 chr1:107558361 A/T cg09367891 chr1:107599246 PRMT6 0.64 5.42 0.44 2.93e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs9814567 0.806 rs4955526 chr3:134317337 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.73 -6.95 -0.53 1.82e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg16497277 chr3:49208875 KLHDC8B -0.55 -5.26 -0.43 6.09e-7 Menarche (age at onset); TGCT cis rs9733 0.596 rs72702552 chr1:150677462 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.81 0.4 4.38e-6 Tonsillectomy; TGCT cis rs11690935 0.595 rs788170 chr2:172919958 T/C cg13550731 chr2:172543902 DYNC1I2 0.69 6.36 0.5 3.49e-9 Schizophrenia; TGCT cis rs798554 0.679 rs2644281 chr7:2886748 A/G cg13628971 chr7:2884303 GNA12 0.54 4.64 0.38 8.74e-6 Height; TGCT cis rs13191362 0.935 rs7767254 chr6:162954674 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.67 5.16 0.42 9.64e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6589563 0.609 rs56225305 chr11:116625362 G/A cg01124546 chr11:117515332 DSCAML1 -0.44 -4.77 -0.39 5.18e-6 Eosinophil counts; TGCT cis rs7726839 0.540 rs72707016 chr5:665148 A/G cg16624210 chr5:671434 TPPP 0.42 4.89 0.4 3.06e-6 Obesity-related traits; TGCT cis rs6545883 0.931 rs9807965 chr2:61732159 T/C cg15711740 chr2:61764176 XPO1 -0.5 -4.51 -0.38 1.46e-5 Tuberculosis; TGCT cis rs11690462 0.514 rs11126465 chr2:26627689 T/C cg11525280 chr2:26624667 C2orf39 0.4 4.76 0.39 5.32e-6 Coronary artery disease; TGCT cis rs4975709 0.589 rs4975746 chr5:1861069 G/A cg14773178 chr5:1868261 NA 0.34 5.8 0.46 5.29e-8 Cardiovascular disease risk factors; TGCT cis rs2239547 0.562 rs6794389 chr3:53096394 A/G cg10802521 chr3:52805072 NEK4 -0.57 -5.24 -0.43 6.68e-7 Schizophrenia; TGCT cis rs2956278 0.717 rs1482397 chr12:84689423 T/C cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs7698623 0.850 rs716808 chr4:88800136 G/T cg27387453 chr4:88533842 DSPP -0.6 -4.53 -0.38 1.35e-5 Cardiovascular disease risk factors; TGCT cis rs7666738 0.830 rs13111977 chr4:98953813 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs62380364 0.626 rs11749912 chr5:88065628 A/G cg22951263 chr5:87985283 NA -0.6 -6.35 -0.5 3.73e-9 Intelligence (multi-trait analysis); TGCT cis rs13082711 0.554 rs73055724 chr3:27380397 T/G cg02860705 chr3:27208620 NA 0.44 6.17 0.48 9.11e-9 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs3087591 0.659 rs7218930 chr17:29640204 A/G cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT cis rs10883723 0.810 rs1409311 chr10:104282160 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs751728 0.544 rs2281820 chr6:33768897 A/G cg00334056 chr6:33755658 LEMD2 -0.26 -4.63 -0.38 9.04e-6 Crohn's disease; TGCT cis rs8056742 0.730 rs35500222 chr16:85098097 C/G cg00229868 chr16:85520891 NA 0.38 4.77 0.39 5.03e-6 Amyotrophic lateral sclerosis; TGCT cis rs501916 1.000 rs586118 chr15:48049776 C/T cg16110827 chr15:48056943 SEMA6D -0.17 -5.33 -0.43 4.5e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs11578119 0.933 rs10919401 chr1:170410369 T/A cg09767346 chr1:170501363 GORAB 0.71 5.65 0.45 1.04e-7 Male-pattern baldness; TGCT cis rs7681440 0.904 rs35424815 chr4:90767877 C/T cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg27588902 chr6:42928151 GNMT -0.49 -5.92 -0.47 3.01e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6951245 0.507 rs11976805 chr7:1138716 C/T cg09177884 chr7:1199841 ZFAND2A -0.67 -5.38 -0.44 3.55e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6582630 0.593 rs7299329 chr12:38447943 G/C cg26384229 chr12:38710491 ALG10B 0.83 7.62 0.56 5.64e-12 Drug-induced liver injury (flucloxacillin); TGCT trans rs916888 0.821 rs199512 chr17:44857352 T/C cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs9467773 0.901 rs1407045 chr6:26476155 A/G cg05738196 chr6:26577821 NA 0.73 8.21 0.59 2.44e-13 Intelligence (multi-trait analysis); TGCT cis rs4747241 0.515 rs11000212 chr10:73955652 C/G cg09661010 chr10:73848153 SPOCK2 -0.42 -5.34 -0.43 4.24e-7 Heschl's gyrus morphology; TGCT cis rs4665809 0.877 rs34536218 chr2:26287376 T/A cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 3e-8 Gut microbiome composition (summer); TGCT cis rs2239547 0.522 rs2581801 chr3:52972907 G/T cg10802521 chr3:52805072 NEK4 0.64 6.17 0.48 8.79e-9 Schizophrenia; TGCT cis rs7523273 0.597 rs4844392 chr1:207991209 C/G cg22525895 chr1:207977042 MIR29B2 -0.44 -6.34 -0.49 3.93e-9 Schizophrenia; TGCT cis rs7824557 0.564 rs2572399 chr8:11234520 A/G cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.97e-9 Retinal vascular caliber; TGCT trans rs2727020 0.658 rs4980442 chr11:49445016 G/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.24 -0.59 2.12e-13 Coronary artery disease; TGCT cis rs10791323 0.604 rs2723605 chr11:133711241 C/G cg03690763 chr11:133734501 NA -0.31 -4.88 -0.4 3.13e-6 Childhood ear infection; TGCT cis rs17376456 0.825 rs12188163 chr5:93250608 A/G cg25358565 chr5:93447407 FAM172A -0.91 -8.1 -0.59 4.46e-13 Diabetic retinopathy; TGCT cis rs1580019 0.547 rs56981934 chr7:32535202 C/G cg06627557 chr7:32535165 LSM5;AVL9 1.15 14.27 0.79 6.08e-28 Cognitive ability; TGCT cis rs8180040 0.620 rs6442055 chr3:47110722 A/G cg27129171 chr3:47204927 SETD2 0.71 8.57 0.61 3.49e-14 Colorectal cancer; TGCT cis rs9560113 0.960 rs1163862 chr13:112174319 C/T cg10483660 chr13:112241077 NA 0.32 4.69 0.39 7.08e-6 Menarche (age at onset); TGCT cis rs114540395 0.925 rs7090062 chr10:103408014 A/G cg18276125 chr10:102749041 C10orf2 0.41 4.79 0.39 4.73e-6 Schizophrenia; TGCT cis rs7568458 0.684 rs1048740 chr2:85764966 A/T cg17127132 chr2:85788382 GGCX 0.52 4.63 0.38 9.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg23205692 chr1:25664452 TMEM50A -0.47 -4.97 -0.41 2.22e-6 Erythrocyte sedimentation rate; TGCT cis rs2549003 1.000 rs13170412 chr5:131823519 A/G cg02551604 chr5:131831745 NA -0.86 -10.87 -0.7 9.47e-20 Asthma (sex interaction); TGCT cis rs7246657 0.722 rs10412510 chr19:38075944 A/G cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs3812831 0.543 rs389108 chr13:114925389 A/G cg08824895 chr13:115047677 UPF3A 0.49 4.65 0.39 8.45e-6 Schizophrenia; TGCT cis rs933688 1.000 rs6866191 chr5:90746852 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.47 0.61 6.09e-14 Smoking behavior; TGCT cis rs909002 0.849 rs6664789 chr1:32072406 C/G cg11573219 chr1:32083031 HCRTR1 -0.5 -6.59 -0.51 1.13e-9 Intelligence (multi-trait analysis); TGCT cis rs9640161 0.750 rs61421252 chr7:150037972 T/C cg17279839 chr7:150038598 RARRES2 0.44 4.78 0.39 4.82e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs4700695 0.614 rs1862600 chr5:65206940 T/C cg21114390 chr5:65439923 SFRS12 0.67 4.69 0.39 7.07e-6 Facial morphology (factor 19); TGCT cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs8141529 0.732 rs5762784 chr22:29171298 C/T cg02153584 chr22:29168773 CCDC117 0.74 6.34 0.49 3.85e-9 Lymphocyte counts; TGCT cis rs586688 1.000 rs525492 chr1:201638858 G/A cg05779441 chr1:201574716 NA 0.29 4.81 0.4 4.25e-6 Obesity-related traits; TGCT cis rs10883723 0.810 rs2296588 chr10:104248087 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs3101457 0.515 rs4658629 chr1:244516754 G/T cg09033006 chr1:244517177 C1orf100 -0.4 -4.46 -0.37 1.8e-5 Smoking behavior; TGCT cis rs7655441 1.000 rs7655441 chr4:80879803 C/T cg02241357 chr4:80885279 ANTXR2 -0.23 -4.46 -0.37 1.81e-5 Neutrophil percentage of white cells; TGCT cis rs13394619 0.744 rs10929759 chr2:11722012 C/G cg07314298 chr2:11723111 GREB1 0.3 5.08 0.41 1.38e-6 Endometriosis; TGCT trans rs459571 0.959 rs456205 chr9:136911146 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.77 -8.29 -0.6 1.58e-13 Platelet distribution width; TGCT cis rs10206020 0.842 rs7590900 chr2:1574902 A/G cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs3733585 0.699 rs12498956 chr4:9950705 G/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.41 -0.5 2.8e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1865760 0.713 rs7766342 chr6:25990674 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 6.94 0.53 1.97e-10 Height; TGCT cis rs2836950 0.565 rs2150414 chr21:40614988 A/G cg06238570 chr21:40685208 BRWD1 -0.62 -6.34 -0.49 3.9e-9 Menarche (age at onset); TGCT cis rs9810089 0.814 rs834305 chr3:136119354 C/T cg12473912 chr3:136751656 NA 0.36 5.04 0.41 1.58e-6 Gestational age at birth (child effect); TGCT cis rs7830933 1.000 rs7830933 chr8:23603324 A/G cg04349084 chr8:23602677 NA 0.25 4.9 0.4 2.96e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs250677 0.522 rs4562031 chr5:148368451 A/G cg18129178 chr5:148520854 ABLIM3 0.36 4.69 0.39 7.23e-6 Breast cancer; TGCT cis rs67311347 0.822 rs11709089 chr3:40351484 C/T cg13683864 chr3:40499215 RPL14 -0.91 -8.88 -0.62 6.23e-15 Renal cell carcinoma; TGCT cis rs6141769 0.542 rs6057632 chr20:31319841 A/G cg13636640 chr20:31349939 DNMT3B -0.52 -4.55 -0.38 1.26e-5 Subjective well-being; TGCT cis rs597539 0.652 rs592697 chr11:68650064 G/A cg04772025 chr11:68637568 NA 0.6 6.67 0.51 7.4e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9527 0.590 rs1926037 chr10:104878010 A/C cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs10791097 0.935 rs4601795 chr11:130729430 T/C cg12179176 chr11:130786555 SNX19 0.63 7.01 0.53 1.36e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7707921 0.767 rs862245 chr5:81585737 A/C cg15871215 chr5:81402204 ATG10 -0.3 -4.67 -0.39 7.64e-6 Breast cancer; TGCT cis rs2806561 0.765 rs668234 chr1:23515467 G/A cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs1538970 1.000 rs2050884 chr1:45830824 A/G cg05343316 chr1:45956843 TESK2 0.64 5.13 0.42 1.08e-6 Platelet count; TGCT cis rs7582180 0.629 rs12612809 chr2:100951616 G/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.503 rs11191321 chr10:104293412 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7916852 0.867 rs10763642 chr10:28388150 G/A cg15286905 chr10:27530250 ACBD5 -0.45 -4.46 -0.37 1.78e-5 Glaucoma (primary open-angle); TGCT cis rs12134133 1.000 rs7518565 chr1:207420343 G/A cg02152968 chr1:207494213 CD55 0.61 4.83 0.4 3.92e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7043114 0.544 rs7852510 chr9:95316359 T/G cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.25 -0.43 6.26e-7 Height; TGCT cis rs6671200 0.573 rs3820345 chr1:95713175 C/T cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs13242816 1.000 rs1049334 chr7:116200380 A/G cg16553024 chr7:116138462 CAV2 0.44 5.16 0.42 9.48e-7 P wave duration; TGCT cis rs9810089 0.814 rs73226190 chr3:136213310 T/C cg12473912 chr3:136751656 NA 0.36 4.95 0.41 2.39e-6 Gestational age at birth (child effect); TGCT cis rs7267979 1.000 rs13038834 chr20:25441433 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs12339966 0.581 rs62529421 chr9:11339611 G/A cg03488587 chr11:64876988 C11orf2 0.32 7.04 0.53 1.16e-10 Systolic blood pressure; TGCT cis rs2295359 0.892 rs72676067 chr1:67658803 G/A cg08029281 chr1:67600428 NA 0.4 4.68 0.39 7.36e-6 Psoriasis; TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 4.99 0.41 1.95e-6 Prudent dietary pattern; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg25703541 chr22:24373054 LOC391322 -0.81 -8.47 -0.61 5.88e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9788721 0.836 rs7181486 chr15:78741618 C/T cg18825076 chr15:78729989 IREB2 0.33 5.23 0.43 6.95e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs9660992 0.512 rs12142402 chr1:205128215 A/T cg03948781 chr1:205179583 DSTYK 0.34 4.47 0.37 1.77e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs250677 0.522 rs4431331 chr5:148353574 A/C cg18129178 chr5:148520854 ABLIM3 -0.36 -4.57 -0.38 1.17e-5 Breast cancer; TGCT cis rs1552244 0.554 rs6796411 chr3:10010681 G/A cg00149659 chr3:10157352 C3orf10 0.64 4.69 0.39 7.12e-6 Alzheimer's disease; TGCT cis rs9311474 0.652 rs411457 chr3:52228150 A/T cg10802521 chr3:52805072 NEK4 0.57 6.25 0.49 6.06e-9 Electroencephalogram traits; TGCT cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg17971929 chr21:40555470 PSMG1 -0.92 -9.42 -0.65 3.21e-16 Cognitive function; TGCT cis rs7213347 0.581 rs11657636 chr17:2053920 C/T cg22033759 chr17:1182267 TUSC5 -0.23 -4.65 -0.39 8.48e-6 Total body bone mineral density; TGCT cis rs2303759 0.918 rs7251704 chr19:49890873 T/G cg22307029 chr19:49891270 CCDC155 0.54 5.09 0.42 1.29e-6 Multiple sclerosis; TGCT cis rs7904368 0.951 rs7905776 chr10:16853609 C/T cg23933602 chr10:16859644 RSU1 0.62 4.57 0.38 1.17e-5 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs11696501 0.688 rs6065859 chr20:44302697 C/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs2692947 0.631 rs2312954 chr2:96772447 C/T cg23100626 chr2:96804247 ASTL -0.42 -5.0 -0.41 1.92e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs12893668 0.703 rs35026580 chr14:104042753 A/G cg26031613 chr14:104095156 KLC1 -0.54 -4.44 -0.37 1.97e-5 Reticulocyte count; TGCT cis rs7223966 0.729 rs2003549 chr17:62008437 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.59 0.38 1.09e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs597539 0.690 rs497149 chr11:68626639 A/T cg06028808 chr11:68637592 NA 0.54 6.92 0.53 2.19e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs172166 0.611 rs203883 chr6:28078356 A/G cg10876282 chr6:28092338 ZSCAN16 0.51 4.63 0.38 9.13e-6 Cardiac Troponin-T levels; TGCT cis rs7918232 0.830 rs7915902 chr10:27410734 T/C cg14442939 chr10:27389572 ANKRD26 0.72 5.35 0.43 4.16e-7 Breast cancer; TGCT cis rs6977660 0.607 rs10243965 chr7:19797893 G/A cg07541023 chr7:19748670 TWISTNB 0.93 5.25 0.43 6.27e-7 Thyroid stimulating hormone; TGCT cis rs3015497 0.904 rs3015501 chr14:51108524 C/T cg04730355 chr14:51134070 SAV1 -0.51 -4.52 -0.38 1.44e-5 Mean platelet volume; TGCT cis rs2742417 1.000 rs2742437 chr3:45743277 G/A cg04837898 chr3:45731254 SACM1L -0.51 -5.23 -0.42 7.13e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1799899 0.826 rs6785596 chr3:133466457 T/A cg18342939 chr3:134203408 ANAPC13;CEP63 0.48 4.91 0.4 2.85e-6 Alcohol consumption (transferrin glycosylation); TGCT cis rs1129187 0.755 rs2296804 chr6:42931261 C/G cg13397359 chr6:42928475 GNMT 0.58 4.89 0.4 3.02e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs3125734 0.633 rs4979774 chr10:63967795 A/T cg05499367 chr10:63213510 TMEM26 -0.33 -4.56 -0.38 1.2e-5 Rheumatoid arthritis; TGCT cis rs9916302 0.851 rs7220650 chr17:37487168 A/G cg15445000 chr17:37608096 MED1 -0.33 -4.7 -0.39 6.89e-6 Glomerular filtration rate (creatinine); TGCT cis rs2880765 0.835 rs4340287 chr15:86043737 A/G cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs10501293 0.746 rs7114320 chr11:43013621 C/G cg03447554 chr11:43094025 NA -0.44 -6.35 -0.5 3.67e-9 Cognitive performance; TGCT cis rs875971 1.000 rs1565531 chr7:65663113 T/A cg18876405 chr7:65276391 NA -0.34 -5.1 -0.42 1.22e-6 Aortic root size; TGCT cis rs2243480 0.706 rs34466769 chr7:65453292 A/C cg18252515 chr7:66147081 NA -0.9 -5.93 -0.47 2.84e-8 Diabetic kidney disease; TGCT cis rs1008375 0.966 rs10006317 chr4:17702525 A/G cg10189774 chr4:17578691 LAP3 0.52 4.47 0.37 1.73e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7819412 0.775 rs4841490 chr8:10936891 T/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.08 -0.54 9.66e-11 Triglycerides; TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs35306767 0.715 rs11253539 chr10:1011347 G/A cg26597838 chr10:835615 NA 0.57 6.42 0.5 2.6e-9 Eosinophil percentage of granulocytes; TGCT cis rs28595532 0.841 rs55744948 chr4:119769243 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs4455778 0.659 rs28522097 chr7:49043054 G/A cg26309511 chr7:48887640 NA 0.42 4.98 0.41 2.08e-6 Lung cancer in never smokers; TGCT cis rs10882165 0.751 rs11817146 chr10:94911300 C/T cg15980076 chr10:94822747 CYP26C1 0.42 4.54 0.38 1.34e-5 Refractive error; TGCT cis rs10193935 0.792 rs13430031 chr2:42499968 C/T cg27598129 chr2:42591480 NA -0.42 -5.7 -0.46 8.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2549003 0.966 rs10065633 chr5:131816716 T/C cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs2562456 0.917 rs2650805 chr19:21687939 T/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT trans rs2727020 0.664 rs4929893 chr11:49196332 C/T cg03929089 chr4:120376271 NA -0.71 -7.91 -0.58 1.22e-12 Coronary artery disease; TGCT cis rs12579753 0.917 rs4842410 chr12:82219225 A/T cg07988820 chr12:82153109 PPFIA2 -0.57 -6.06 -0.48 1.54e-8 Resting heart rate; TGCT cis rs2268241 0.938 rs9978166 chr21:34770516 A/G cg14850771 chr21:34775459 IFNGR2 0.6 5.31 0.43 4.82e-7 Obesity-related traits; TGCT cis rs11690935 0.959 rs1474074 chr2:172659852 G/A cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs67981189 0.513 rs2526856 chr14:71412717 A/G cg15910301 chr14:71632612 NA 0.26 4.62 0.38 9.39e-6 Schizophrenia; TGCT trans rs62103177 0.525 rs10438902 chr18:77745640 A/G cg05926928 chr17:57297772 GDPD1 -0.75 -6.87 -0.53 2.8e-10 Opioid sensitivity; TGCT cis rs950169 0.810 rs2879976 chr15:85109578 G/A cg17173187 chr15:85201210 NMB 0.48 5.02 0.41 1.75e-6 Schizophrenia; TGCT cis rs1577917 0.740 rs7771612 chr6:86264374 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.54 4.87 0.4 3.29e-6 Response to antipsychotic treatment; TGCT cis rs7772486 0.875 rs9403770 chr6:146423334 C/T cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7698623 0.850 rs6532019 chr4:88768672 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.28e-6 Cardiovascular disease risk factors; TGCT cis rs12497850 0.931 rs13064784 chr3:49135961 C/G cg07636037 chr3:49044803 WDR6 0.96 10.9 0.7 8.39e-20 Parkinson's disease; TGCT cis rs7666738 0.861 rs5014702 chr4:99052102 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.15 0.42 1.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs60733400 0.817 rs4648657 chr1:2560735 A/G cg18854424 chr1:2615690 NA -0.45 -5.13 -0.42 1.07e-6 Multiple sclerosis; TGCT cis rs112217694 1.000 rs75027425 chr4:104649311 C/T cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs10254284 0.959 rs10275989 chr7:28159696 A/G cg23620719 chr7:28220237 JAZF1 0.53 4.81 0.4 4.26e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs921968 0.643 rs535830 chr2:219372233 C/G cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs362272 0.505 rs13104157 chr4:3366950 T/C cg06533319 chr4:3265114 C4orf44 -0.26 -5.28 -0.43 5.71e-7 Serum sulfate level; TGCT cis rs12530845 0.945 rs76298187 chr7:135334534 A/G cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg26531700 chr6:26746687 NA -0.67 -6.48 -0.5 1.97e-9 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.559 rs183599 chr6:88061024 C/T cg08069147 chr6:88032118 GJB7;C6orf162 0.68 6.88 0.53 2.68e-10 Monocyte percentage of white cells; TGCT cis rs1395 0.778 rs56364136 chr2:27451429 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.68 0.51 7.27e-10 Blood metabolite levels; TGCT cis rs6901250 0.851 rs6938235 chr6:117147946 G/T cg12892004 chr6:117198278 RFX6 0.55 6.8 0.52 3.85e-10 C-reactive protein levels; TGCT cis rs9926296 0.607 rs11076629 chr16:89875259 T/C cg03388025 chr16:89894329 SPIRE2 0.36 5.12 0.42 1.15e-6 Vitiligo; TGCT cis rs546131 0.928 rs572690 chr11:34833614 A/G cg06937548 chr11:34938143 PDHX;APIP 0.62 5.56 0.45 1.57e-7 Lung disease severity in cystic fibrosis; TGCT cis rs4676380 0.927 rs1583259 chr2:241644934 G/T cg21930842 chr2:241631663 AQP12A 0.25 4.65 0.39 8.43e-6 Response to metformin (IC50); TGCT cis rs12220238 0.908 rs73284278 chr10:76011751 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.36 0.55 2.18e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs250677 1.000 rs190378 chr5:148434275 G/T cg18129178 chr5:148520854 ABLIM3 -0.44 -6.39 -0.5 3.09e-9 Breast cancer; TGCT cis rs4845570 0.920 rs6694952 chr1:151760131 T/C cg07092448 chr1:151763213 TDRKH 1.15 9.69 0.66 7.09e-17 Coronary artery disease; TGCT cis rs782590 0.967 rs17798852 chr2:55805172 A/C cg03859395 chr2:55845619 SMEK2 0.92 11.39 0.72 5.08e-21 Metabolic syndrome; TGCT cis rs1215050 0.846 rs783923 chr4:98968686 C/T cg05340658 chr4:99064831 C4orf37 -0.46 -5.55 -0.45 1.67e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11676348 0.714 rs4674254 chr2:218986077 T/C cg00012203 chr2:219082015 ARPC2 -0.52 -4.98 -0.41 2.08e-6 Ulcerative colitis; TGCT cis rs7568458 0.905 rs6547620 chr2:85755928 C/T cg02493740 chr2:85810744 VAMP5 -0.27 -4.81 -0.4 4.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4455778 0.543 rs4357242 chr7:49067599 T/C cg26309511 chr7:48887640 NA 0.51 6.63 0.51 9.47e-10 Lung cancer in never smokers; TGCT trans rs916888 0.773 rs199535 chr17:44822662 A/G cg22433210 chr17:43662623 NA 0.98 6.85 0.52 3.13e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6138458 0.717 rs2179732 chr20:25000446 A/T cg26195577 chr20:24973756 C20orf3 1.02 9.48 0.65 2.3e-16 Blood protein levels; TGCT cis rs9611565 0.694 rs4822032 chr22:41925535 T/C cg03806693 chr22:41940476 POLR3H -0.97 -10.77 -0.7 1.72e-19 Vitiligo; TGCT cis rs1215050 0.791 rs1215049 chr4:98848280 C/T cg17366294 chr4:99064904 C4orf37 0.54 5.66 0.45 9.77e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7264396 0.790 rs2425096 chr20:34308588 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.96e-7 Total cholesterol levels; TGCT cis rs1218582 0.772 rs2335408 chr1:154915977 G/A cg06221963 chr1:154839813 KCNN3 -0.71 -11.68 -0.72 1.06e-21 Prostate cancer; TGCT cis rs3806843 0.576 rs246045 chr5:140329884 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6866344 0.561 rs55974982 chr5:178141421 G/A cg10224037 chr5:178157518 ZNF354A 0.98 9.87 0.66 2.66e-17 Neutrophil percentage of white cells; TGCT cis rs7666738 0.830 rs11097609 chr4:99011707 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.655 rs2330103 chr21:46694514 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.62 6.01 0.47 1.93e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6952809 0.532 rs6956223 chr7:2431331 T/C cg23289794 chr7:2394357 EIF3B -0.82 -7.14 -0.54 7.04e-11 Multiple sclerosis; TGCT trans rs4819388 0.751 rs2838531 chr21:45638586 C/T cg17383793 chr5:52405638 MOCS2 -0.71 -6.73 -0.52 5.65e-10 Celiac disease; TGCT cis rs1891275 0.515 rs6583784 chr10:93491576 A/G cg07889827 chr10:93443413 NA 0.3 6.29 0.49 4.85e-9 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg04944784 chr2:26401820 FAM59B -0.86 -6.26 -0.49 5.74e-9 Gut microbiome composition (summer); TGCT cis rs7681440 0.874 rs7687945 chr4:90764699 C/T cg20003494 chr4:90757398 SNCA -0.63 -6.09 -0.48 1.3e-8 Dementia with Lewy bodies; TGCT cis rs13242816 1.000 rs13247987 chr7:116113344 A/C cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs13191362 0.935 rs13219926 chr6:163004213 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9926296 0.656 rs2376883 chr16:89826926 A/G cg26513180 chr16:89883248 FANCA 0.7 6.76 0.52 4.76e-10 Vitiligo; TGCT cis rs603424 0.509 rs598133 chr10:102082245 A/G cg22671421 chr10:102507979 PAX2 0.56 4.66 0.39 8e-6 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs73198271 0.740 rs10098636 chr8:8647324 C/T cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs4975709 0.610 rs4975704 chr5:1859807 C/A cg15595755 chr5:1867978 NA 0.45 5.13 0.42 1.08e-6 Cardiovascular disease risk factors; TGCT cis rs1670533 1.000 rs629260 chr4:1086764 A/G cg27284194 chr4:1044797 NA 0.68 5.95 0.47 2.59e-8 Recombination rate (females); TGCT cis rs12142240 0.660 rs72886903 chr1:46813860 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs1371867 0.817 rs7846076 chr8:101327629 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs62402013 1 rs62402013 chr6:26915000 A/G cg02458000 chr6:26745757 NA 0.6 5.33 0.43 4.42e-7 Schizophrenia; TGCT cis rs4499344 0.556 rs259228 chr19:33134635 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.81 8.16 0.59 3.17e-13 Mean platelet volume; TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg24503407 chr1:205819492 PM20D1 0.58 8.13 0.59 3.84e-13 Menarche (age at onset); TGCT trans rs1814175 0.645 rs1721996 chr11:49915527 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT trans rs7613875 0.620 rs7624030 chr3:50071279 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.71 -0.62 1.65e-14 Body mass index; TGCT cis rs2288884 0.943 rs3752120 chr19:52552021 C/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs11809207 0.501 rs2232654 chr1:26496870 A/G cg24519413 chr1:26490540 NA 0.22 4.6 0.38 1.02e-5 Height; TGCT trans rs1496653 0.602 rs34882744 chr3:23626018 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2718812 0.766 rs1822744 chr3:133366227 A/G cg16414030 chr3:133502952 NA -0.4 -5.19 -0.42 8.27e-7 Iron status biomarkers; TGCT cis rs459571 0.959 rs455381 chr9:136905577 C/A cg13789015 chr9:136890014 NCRNA00094 0.41 7.58 0.56 7.09e-12 Platelet distribution width; TGCT cis rs1552244 0.882 rs55808392 chr3:10054681 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs17401966 1.000 rs12734068 chr1:10376803 G/A cg19773385 chr1:10388646 KIF1B -0.22 -4.58 -0.38 1.12e-5 Hepatocellular carcinoma; TGCT cis rs1008375 1.000 rs11724495 chr4:17621310 G/A cg16339924 chr4:17578868 LAP3 0.64 5.32 0.43 4.72e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7412746 0.611 rs10788794 chr1:150728676 T/C cg09365446 chr1:150670422 GOLPH3L 0.33 4.78 0.39 4.8e-6 Melanoma; TGCT cis rs74233809 1.000 rs11191454 chr10:104660004 A/G cg05855489 chr10:104503620 C10orf26 0.75 4.47 0.37 1.72e-5 Birth weight; TGCT cis rs1552244 0.572 rs73117481 chr3:10160132 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs4727027 0.704 rs4727031 chr7:148908305 T/C cg23583168 chr7:148888333 NA -0.86 -11.0 -0.7 4.61e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9325144 0.555 rs1813392 chr12:38692203 C/T cg26384229 chr12:38710491 ALG10B -0.65 -6.23 -0.49 6.73e-9 Morning vs. evening chronotype; TGCT cis rs9291683 0.620 rs717615 chr4:10104670 C/T cg00071950 chr4:10020882 SLC2A9 0.48 5.25 0.43 6.48e-7 Bone mineral density; TGCT cis rs6088590 0.965 rs6088620 chr20:33412022 A/G cg24642439 chr20:33292090 TP53INP2 0.68 6.09 0.48 1.32e-8 Coronary artery disease; TGCT cis rs904251 0.600 rs4714068 chr6:37455642 A/C cg25019722 chr6:37503610 NA -0.47 -6.95 -0.53 1.87e-10 Cognitive performance; TGCT cis rs7178572 0.789 rs4886869 chr15:77799657 A/G cg22256960 chr15:77711686 NA -0.78 -8.06 -0.59 5.4e-13 Type 2 diabetes; TGCT cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg26531700 chr6:26746687 NA -0.57 -5.21 -0.42 7.62e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4689388 0.926 rs5018647 chr4:6292799 A/C cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs9388451 0.513 rs1268069 chr6:126039994 A/C cg05039488 chr6:79577232 IRAK1BP1 -0.66 -6.78 -0.52 4.43e-10 Brugada syndrome; TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs7826238 0.653 rs2979202 chr8:8344127 T/C cg06636001 chr8:8085503 FLJ10661 0.63 5.8 0.46 5.09e-8 Systolic blood pressure; TGCT cis rs9660180 0.868 rs72634846 chr1:1704915 C/G cg20999797 chr1:1681921 NA 0.18 4.78 0.39 4.93e-6 Body mass index; TGCT cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg00786635 chr1:25594202 NA -0.52 -5.56 -0.45 1.59e-7 Erythrocyte sedimentation rate; TGCT cis rs7312933 0.558 rs1051453 chr12:42852217 C/T cg19980929 chr12:42632907 YAF2 0.43 6.19 0.49 8.26e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs1552244 0.608 rs9837460 chr3:10049922 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.7 0.39 6.81e-6 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs7682991 chr4:98982595 C/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2455799 0.573 rs2470546 chr3:15733897 T/C cg16303742 chr3:15540471 COLQ -0.26 -4.8 -0.4 4.49e-6 Mean platelet volume; TGCT cis rs7634476 1 rs7634476 chr3:136398387 A/G cg12473912 chr3:136751656 NA -0.34 -4.92 -0.4 2.71e-6 Neuroticism; TGCT trans rs7698623 0.850 rs4693892 chr4:88796983 T/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs7552404 0.731 rs10873787 chr1:76367797 G/A cg03433033 chr1:76189801 ACADM 0.77 7.43 0.56 1.5e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs881375 1.000 rs6478484 chr9:123652380 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.38 0.44 3.52e-7 Rheumatoid arthritis; TGCT cis rs66573146 1.000 rs56178503 chr4:6961748 C/T cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs8014204 0.868 rs2230237 chr14:75359670 G/A cg06637938 chr14:75390232 RPS6KL1 -0.75 -7.22 -0.54 4.62e-11 Caffeine consumption; TGCT cis rs2224391 0.628 rs2773317 chr6:5254509 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.99 -6.48 -0.5 1.99e-9 Height; TGCT cis rs67366981 0.778 rs3952319 chr14:77684379 A/T cg22824376 chr14:77648248 TMEM63C 0.73 4.71 0.39 6.61e-6 Obsessive-compulsive symptoms; TGCT cis rs7953508 0.506 rs3782415 chr12:93967755 T/C cg18151635 chr12:93972918 NA -0.19 -4.52 -0.38 1.41e-5 Pubertal anthropometrics; TGCT cis rs7213347 0.678 rs11658797 chr17:2088969 T/G cg13315690 chr17:1944831 OVCA2;DPH1 -0.38 -4.8 -0.4 4.44e-6 Total body bone mineral density; TGCT cis rs7633770 0.805 rs11710264 chr3:46661579 T/C cg11219411 chr3:46661640 NA 0.36 5.27 0.43 5.86e-7 Coronary artery disease; TGCT cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg02487422 chr3:49467188 NICN1 0.54 5.26 0.43 6.11e-7 Menarche (age at onset); TGCT cis rs1862618 0.671 rs2591970 chr5:56232595 T/C cg24531977 chr5:56204891 C5orf35 0.68 7.22 0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs7552404 1.000 rs4949874 chr1:76161889 T/C cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7975161 0.938 rs4964271 chr12:104652441 T/C cg25273343 chr12:104657179 TXNRD1 -0.36 -5.28 -0.43 5.53e-7 Toenail selenium levels; TGCT cis rs3784262 0.631 rs4646566 chr15:58348173 G/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2404602 0.684 rs12591622 chr15:76930655 A/T cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs9811920 0.535 rs792837 chr3:99477182 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.39 4.6 0.38 1.04e-5 Axial length; TGCT cis rs6543140 0.964 rs2160200 chr2:103033963 G/T cg09003973 chr2:102972529 NA 0.59 4.95 0.41 2.39e-6 Blood protein levels; TGCT cis rs7772486 0.875 rs2814877 chr6:146299763 C/G cg13319975 chr6:146136371 FBXO30 -0.53 -4.71 -0.39 6.53e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12791968 0.659 rs12808379 chr11:45009273 C/G cg11846598 chr11:44996168 LOC221122 -0.32 -5.2 -0.42 8.09e-7 Inhibitory control; TGCT cis rs2657888 1.000 rs73118833 chr12:56941734 C/A cg23002907 chr12:56915593 RBMS2 -0.45 -6.07 -0.48 1.44e-8 Adiponectin levels; TGCT cis rs2204008 0.837 rs11172728 chr12:38070042 C/A cg13010199 chr12:38710504 ALG10B 0.61 4.91 0.4 2.86e-6 Bladder cancer; TGCT cis rs7677751 0.806 rs7681399 chr4:55090886 T/G cg17187183 chr4:55093834 PDGFRA 0.53 6.8 0.52 3.9e-10 Corneal astigmatism; TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs9611565 0.694 rs11090056 chr22:42095904 A/C cg03806693 chr22:41940476 POLR3H 0.96 9.69 0.66 7.24e-17 Vitiligo; TGCT cis rs514406 0.679 rs11206006 chr1:53218380 A/G cg24675658 chr1:53192096 ZYG11B 0.88 11.43 0.72 4.12e-21 Monocyte count; TGCT cis rs904251 0.797 rs1757177 chr6:37486370 C/T cg25019722 chr6:37503610 NA -0.52 -6.77 -0.52 4.49e-10 Cognitive performance; TGCT cis rs1059312 1.000 rs9738216 chr12:129281788 C/T cg09035930 chr12:129282057 SLC15A4 0.55 10.83 0.7 1.22e-19 Systemic lupus erythematosus; TGCT cis rs6922617 0.786 rs57437999 chr6:41345126 A/G cg07798131 chr6:41471673 NA 0.98 4.85 0.4 3.6e-6 Alzheimer's disease biomarkers; TGCT cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg22800045 chr5:56110881 MAP3K1 0.53 4.43 0.37 2.01e-5 Initial pursuit acceleration; TGCT cis rs9522267 0.559 rs9522300 chr13:112236668 C/G cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs8077577 0.895 rs16960996 chr17:18110559 A/G cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT trans rs6089829 0.888 rs4809468 chr20:61673566 T/C cg13615516 chr5:77269221 NA 0.73 8.42 0.6 7.74e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs797680 0.786 rs7525248 chr1:93828523 T/A cg17826107 chr1:92977322 EVI5 -0.24 -5.63 -0.45 1.13e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2456568 0.867 rs2456569 chr11:93691393 C/A cg17595323 chr11:93583763 C11orf90 -0.46 -6.13 -0.48 1.07e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs17376456 0.825 rs35426871 chr5:93291613 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs7582180 0.700 rs2309852 chr2:100982527 T/C cg14675211 chr2:100938903 LONRF2 0.48 4.54 0.38 1.32e-5 Intelligence (multi-trait analysis); TGCT cis rs9911578 0.813 rs8066773 chr17:56601552 A/G cg12560992 chr17:57184187 TRIM37 0.75 8.23 0.59 2.22e-13 Intelligence (multi-trait analysis); TGCT cis rs2025751 0.666 rs10214606 chr6:51686081 G/A cg23457901 chr6:52402140 TRAM2 -0.22 -4.52 -0.38 1.43e-5 Intraocular pressure; TGCT cis rs4804368 0.714 rs4804372 chr19:7191712 A/G cg10148591 chr19:7197021 INSR 0.38 4.61 0.38 9.78e-6 Renal cell carcinoma; TGCT cis rs12134245 0.776 rs6688261 chr1:91987034 C/T cg25838465 chr1:92012736 NA -0.4 -6.93 -0.53 2.05e-10 Breast cancer; TGCT cis rs10501293 0.642 rs1489198 chr11:43000335 G/A cg03447554 chr11:43094025 NA 0.44 6.48 0.5 1.92e-9 Cognitive performance; TGCT cis rs763121 0.815 rs4821799 chr22:39021326 T/G cg06022373 chr22:39101656 GTPBP1 0.72 7.01 0.53 1.35e-10 Menopause (age at onset); TGCT cis rs986417 0.786 rs7156379 chr14:61110634 G/C cg27398547 chr14:60952738 C14orf39 1.61 8.49 0.61 5.37e-14 Gut microbiota (bacterial taxa); TGCT cis rs4906332 1.000 rs17617935 chr14:103952886 A/T cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs1799949 0.965 rs4239149 chr17:41328095 A/G cg05368731 chr17:41323189 NBR1 -1.02 -11.38 -0.71 5.62e-21 Menopause (age at onset); TGCT cis rs13108904 0.901 rs1316394 chr4:1315820 G/A cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs7959452 0.901 rs1384 chr12:69747834 C/T cg11871910 chr12:69753446 YEATS4 0.76 8.31 0.6 1.44e-13 Blood protein levels; TGCT cis rs17253792 0.822 rs12100753 chr14:56042870 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs9443645 0.869 rs9361467 chr6:79621098 A/G cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs12134133 0.962 rs17258843 chr1:207414732 C/T cg02152968 chr1:207494213 CD55 0.6 4.67 0.39 7.74e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs877282 0.898 rs12358966 chr10:758703 A/G cg17470449 chr10:769945 NA 0.36 5.32 0.43 4.77e-7 Uric acid levels; TGCT cis rs114540395 0.858 rs117998275 chr10:103183891 T/G cg18276125 chr10:102749041 C10orf2 0.36 4.44 0.37 1.98e-5 Schizophrenia; TGCT cis rs899997 0.773 rs8032156 chr15:78964498 A/G cg00061860 chr15:78953028 NA -0.32 -5.07 -0.41 1.41e-6 Coronary artery disease or large artery stroke; TGCT cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs7666738 0.800 rs2839836 chr4:98970512 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6459680 0.583 rs6957217 chr7:156268109 C/T cg02321112 chr7:156810523 NA -0.31 -4.64 -0.38 8.79e-6 Glomerular filtration rate (creatinine); TGCT cis rs1670533 1.000 rs1010342 chr4:1068819 C/T cg27284194 chr4:1044797 NA 0.67 5.98 0.47 2.17e-8 Recombination rate (females); TGCT cis rs7249142 0.562 rs10417796 chr19:19287072 A/G cg19540702 chr19:19281175 LOC729991-MEF2B;MEF2B -0.45 -4.49 -0.37 1.6e-5 IgG glycosylation; TGCT cis rs8067545 0.750 rs4925072 chr17:19956899 C/T cg13482628 chr17:19912719 NA -0.55 -4.93 -0.4 2.57e-6 Schizophrenia; TGCT cis rs11578119 0.689 rs2027020 chr1:170387134 A/G cg09767346 chr1:170501363 GORAB 0.57 4.74 0.39 5.75e-6 Male-pattern baldness; TGCT cis rs10851411 0.789 rs1900920 chr15:42768198 C/T cg23803468 chr15:43513504 EPB42 -0.24 -4.67 -0.39 7.77e-6 Glucose homeostasis traits; TGCT cis rs7180079 0.502 rs6494466 chr15:64508763 A/G cg02848875 chr15:64387786 SNX1 0.38 5.84 0.46 4.24e-8 Monocyte count; TGCT cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg12756686 chr19:29218302 NA 0.76 6.45 0.5 2.29e-9 Methadone dose in opioid dependence; TGCT cis rs11785400 1.000 rs4327844 chr8:143733540 C/T cg10596483 chr8:143751796 JRK -0.52 -5.7 -0.46 8.31e-8 Schizophrenia; TGCT trans rs6561151 0.681 rs17571812 chr13:44472462 G/A cg12856521 chr11:46389249 DGKZ 0.77 7.12 0.54 7.74e-11 Crohn's disease; TGCT cis rs28595532 0.920 rs114168088 chr4:119772666 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9733 0.596 rs12086630 chr1:150650955 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs7818688 0.697 rs77805255 chr8:95983566 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7539409 0.764 rs4001465 chr1:84285304 T/C cg10977910 chr1:84465055 TTLL7 0.98 5.58 0.45 1.42e-7 Alzheimer's disease; TGCT cis rs7809950 0.817 rs4727679 chr7:107085018 T/C cg23024343 chr7:107201750 COG5 -0.48 -7.05 -0.54 1.08e-10 Coronary artery disease; TGCT trans rs1496653 0.602 rs34732257 chr3:23386571 T/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs2730245 0.569 rs1188955 chr7:158690866 A/G cg11984989 chr7:158649758 WDR60 1.1 10.21 0.68 3.87e-18 Height; TGCT cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.11 14.68 0.8 6.95e-29 Height; TGCT cis rs7662987 0.517 rs2851265 chr4:100029684 A/G cg12011299 chr4:100065546 ADH4 0.42 4.95 0.41 2.37e-6 Smoking initiation; TGCT cis rs2439831 0.867 rs486301 chr15:43836949 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.98 7.46 0.56 1.35e-11 Lung cancer in ever smokers; TGCT cis rs1784581 0.761 rs6455791 chr6:162418533 G/A cg17173639 chr6:162384350 PARK2 0.44 7.6 0.56 6.3e-12 Itch intensity from mosquito bite; TGCT cis rs11785400 0.762 rs9694556 chr8:143727841 A/G cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs6964587 0.967 rs6465353 chr7:91779971 G/T cg17063962 chr7:91808500 NA -0.84 -9.58 -0.65 1.34e-16 Breast cancer; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg23131131 chr22:24373011 LOC391322 -0.84 -9.16 -0.64 1.33e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs75686122 0.892 rs76161982 chr8:104659745 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs2832077 0.527 rs2705690 chr21:30239245 T/A cg24692254 chr21:30365293 RNF160 0.59 4.98 0.41 2.04e-6 Cognitive test performance; TGCT cis rs7659604 0.605 rs2071486 chr4:122740162 C/T cg20573242 chr4:122745356 CCNA2 0.58 5.37 0.43 3.73e-7 Type 2 diabetes; TGCT cis rs2730245 0.636 rs2657382 chr7:158650941 G/A cg11984989 chr7:158649758 WDR60 1.05 9.79 0.66 4.1e-17 Height; TGCT cis rs1799949 0.929 rs4792988 chr17:41437547 T/C cg05368731 chr17:41323189 NBR1 1.11 11.95 0.73 2.23e-22 Menopause (age at onset); TGCT cis rs939574 1.000 rs1109866 chr2:220083279 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.04 -6.24 -0.49 6.22e-9 Platelet distribution width; TGCT cis rs2224391 0.784 rs59548069 chr6:5276595 T/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.8 -4.92 -0.4 2.64e-6 Height; TGCT cis rs9831754 0.906 rs7621811 chr3:78388816 G/A cg06138941 chr3:78371609 NA -0.49 -5.4 -0.44 3.25e-7 Calcium levels; TGCT cis rs589448 0.902 rs528974 chr12:69765918 A/T cg11871910 chr12:69753446 YEATS4 0.88 10.41 0.68 1.28e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs10193935 0.901 rs13413617 chr2:42537546 A/G cg27598129 chr2:42591480 NA -0.34 -4.79 -0.4 4.65e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6840360 0.582 rs7691601 chr4:152321631 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.68e-9 Intelligence (multi-trait analysis); TGCT cis rs2303745 0.544 rs12710308 chr19:17395879 T/A cg04248312 chr19:17393744 ANKLE1 -0.34 -5.7 -0.46 8.29e-8 Systemic lupus erythematosus; TGCT cis rs1568889 0.838 rs11030185 chr11:28041904 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.94 11.28 0.71 9.55e-21 Bipolar disorder; TGCT cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg18305652 chr10:134549665 INPP5A 0.31 4.94 0.41 2.44e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1205863 1.000 rs1205867 chr6:11943991 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs9911578 0.967 rs302842 chr17:56728102 C/G cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs9660180 0.846 rs10907195 chr1:1713348 C/T cg03396347 chr1:1875803 NA 0.35 5.75 0.46 6.45e-8 Body mass index; TGCT cis rs17253792 0.822 rs75995456 chr14:56073194 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs709400 0.628 rs3783394 chr14:103858673 G/A cg26031613 chr14:104095156 KLC1 0.85 9.32 0.64 5.53e-16 Body mass index; TGCT cis rs208520 0.690 rs12201219 chr6:66748862 A/T cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs16958440 0.867 rs79285649 chr18:44699019 A/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs11696501 0.688 rs6065851 chr20:44279034 C/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs7666738 0.830 rs13138051 chr4:99050367 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs10506458 0.915 rs56321182 chr12:63392023 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs9309473 0.519 rs2421584 chr2:73898852 G/A cg20560298 chr2:73613845 ALMS1 0.41 4.51 0.38 1.46e-5 Metabolite levels; TGCT cis rs151227923 1 rs151227923 chr7:155106564 C/T cg14927855 chr7:155151427 NA 0.49 6.82 0.52 3.51e-10 Stem cell growth factor beta levels; TGCT cis rs9611565 0.592 rs5758406 chr22:42076641 A/G cg17554472 chr22:41940697 POLR3H 0.5 5.36 0.43 3.92e-7 Vitiligo; TGCT cis rs3749237 0.595 rs885592 chr3:49497883 T/G cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs9674544 0.646 rs8069452 chr17:47140999 A/G cg07075026 chr17:47091521 IGF2BP1 0.41 4.58 0.38 1.13e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs7043114 0.525 rs7853859 chr9:95151377 A/G cg14311495 chr9:95764742 FGD3 -0.21 -4.64 -0.38 8.89e-6 Height; TGCT cis rs4455778 0.626 rs10230504 chr7:49052918 G/T cg26309511 chr7:48887640 NA 0.45 5.25 0.43 6.32e-7 Lung cancer in never smokers; TGCT cis rs7786808 0.586 rs7794256 chr7:158206214 T/G cg01191920 chr7:158217561 PTPRN2 0.39 5.8 0.46 5.29e-8 Obesity-related traits; TGCT cis rs6121246 0.909 rs6119651 chr20:30259246 G/T cg13852791 chr20:30311386 BCL2L1 0.79 5.72 0.46 7.61e-8 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -4.72 -0.39 6.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs3806843 0.517 rs246031 chr5:140333107 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs700651 0.789 rs1371663 chr2:198900305 C/T cg00792783 chr2:198669748 PLCL1 -0.58 -4.96 -0.41 2.25e-6 Intracranial aneurysm; TGCT cis rs7246657 0.722 rs2909100 chr19:38212680 C/T cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs2956278 0.717 rs10161500 chr12:84685521 A/T cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2859741 0.967 rs507460 chr1:37493206 C/G cg09363841 chr1:37513479 NA 0.2 4.71 0.39 6.5e-6 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs2486288 0.656 rs9920290 chr15:45548035 G/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs4808199 0.948 rs8108647 chr19:19427623 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.58 0.45 1.44e-7 Nonalcoholic fatty liver disease; TGCT cis rs9818758 0.607 rs9855123 chr3:49229457 C/T cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs12220238 1.000 rs11000916 chr10:75953909 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs734999 0.545 rs7368072 chr1:2556125 C/T cg18854424 chr1:2615690 NA 0.45 5.15 0.42 1e-6 Ulcerative colitis; TGCT cis rs7552404 1.000 rs72686191 chr1:76218319 G/T cg10523679 chr1:76189770 ACADM 0.92 9.55 0.65 1.53e-16 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs877282 0.700 rs816311 chr10:796490 C/A cg22713356 chr15:30763199 NA 0.97 8.41 0.6 8.08e-14 Uric acid levels; TGCT cis rs2637266 1.000 rs35991266 chr10:78378733 A/G cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs6693567 0.545 rs1260391 chr1:150373077 T/C cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs6967414 0.786 rs6948965 chr7:6758547 G/A cg00387323 chr7:6746715 ZNF12 0.76 4.65 0.39 8.23e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs56235845 0.694 rs6875461 chr5:176754665 C/T cg06060754 chr5:176797920 RGS14 -0.4 -6.25 -0.49 6.15e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs6893807 0.943 rs13166120 chr5:87948883 G/A cg24804195 chr5:87968844 LOC645323 0.75 5.48 0.44 2.28e-7 Body mass index; TGCT cis rs2243480 1.000 rs10807701 chr7:65724686 C/A cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs71444571 1 rs71444571 chr12:123771015 G/A cg00376283 chr12:123451042 ABCB9 -0.67 -4.52 -0.38 1.42e-5 Lymphocyte percentage of white cells; TGCT cis rs910316 1.000 rs4903281 chr14:75554361 G/C cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs42648 0.755 rs1557650 chr7:89971556 A/C cg25739043 chr7:89950458 NA -0.67 -6.51 -0.5 1.65e-9 Homocysteine levels; TGCT cis rs17401966 0.838 rs4846212 chr1:10370312 T/C cg19773385 chr1:10388646 KIF1B -0.22 -4.7 -0.39 6.81e-6 Hepatocellular carcinoma; TGCT cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg23708337 chr7:1209742 NA 0.63 6.03 0.48 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7267979 0.739 rs6138555 chr20:25242910 G/A cg03522245 chr20:25566470 NINL 0.57 5.67 0.45 9.54e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1005277 0.579 rs2474563 chr10:38375938 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.4 0.6 8.55e-14 Extrinsic epigenetic age acceleration; TGCT cis rs12220898 0.749 rs4838486 chr10:50484962 G/A cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs2404602 0.716 rs4886813 chr15:76838221 C/T cg22467129 chr15:76604101 ETFA 0.42 4.77 0.39 5.1e-6 Blood metabolite levels; TGCT cis rs17253792 0.822 rs7145064 chr14:56088860 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs12497850 0.931 rs7636057 chr3:48992582 C/T cg06212747 chr3:49208901 KLHDC8B 0.6 5.43 0.44 2.82e-7 Parkinson's disease; TGCT trans rs117132860 0.661 rs10275574 chr7:17118448 C/G cg25519926 chr7:130132360 MEST;MESTIT1 0.95 6.72 0.52 5.93e-10 Cutaneous squamous cell carcinoma; TGCT cis rs12220898 0.749 rs7068959 chr10:50468696 A/C cg09603381 chr10:49954066 WDFY4 0.39 4.49 0.37 1.58e-5 Inflammatory biomarkers; TGCT cis rs9929218 0.748 rs34592833 chr16:68739125 G/A cg01251360 chr16:68772225 CDH1 0.29 4.68 0.39 7.37e-6 Colorectal cancer; TGCT cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT trans rs9650657 0.547 rs11250099 chr8:10818657 C/T cg15556689 chr8:8085844 FLJ10661 0.92 10.0 0.67 1.29e-17 Neuroticism; TGCT cis rs7666738 0.606 rs28481322 chr4:99086638 T/C cg17366294 chr4:99064904 C4orf37 0.57 5.34 0.43 4.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12765878 0.934 rs11191841 chr10:105639611 C/T cg11005552 chr10:105648138 OBFC1 -0.41 -6.71 -0.52 6.34e-10 Coronary artery disease; TGCT cis rs3902035 0.964 rs62423966 chr6:119010144 A/C cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs11785400 0.793 rs4736366 chr8:143742413 C/T cg10596483 chr8:143751796 JRK 0.55 5.43 0.44 2.82e-7 Schizophrenia; TGCT cis rs6750047 0.605 rs1374191 chr2:38265420 T/G cg07380506 chr2:38303506 CYP1B1 -0.59 -5.34 -0.43 4.23e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs739496 0.895 rs614591 chr12:111946435 A/G cg10833066 chr12:111807467 FAM109A 0.37 5.59 0.45 1.4e-7 Platelet count; TGCT cis rs8002180 0.877 rs7325813 chr13:95920679 T/A cg24476569 chr13:95954382 ABCC4 0.39 4.97 0.41 2.2e-6 Blood metabolite levels; TGCT cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg13393036 chr8:95962371 TP53INP1 -0.55 -6.79 -0.52 4.12e-10 Type 2 diabetes; TGCT cis rs11690935 0.959 rs7597387 chr2:172577116 T/C cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT trans rs208520 0.874 rs208512 chr6:66943869 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.93 -0.67 1.84e-17 Exhaled nitric oxide output; TGCT cis rs909674 0.818 rs5757680 chr22:39844793 C/T cg02038168 chr22:39784481 NA 0.7 5.42 0.44 3.03e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg27454412 chr7:1067447 C7orf50 0.57 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg03188948 chr7:1209495 NA 0.44 5.79 0.46 5.49e-8 Longevity;Endometriosis; TGCT cis rs7681440 0.775 rs6848181 chr4:90807252 T/C cg26578617 chr4:90757533 SNCA -0.45 -4.63 -0.38 9.12e-6 Dementia with Lewy bodies; TGCT cis rs968567 0.559 rs174548 chr11:61571348 C/G cg01500311 chr11:61656094 FADS3 -0.28 -4.82 -0.4 4.17e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg07061783 chr6:25882402 NA -0.55 -5.18 -0.42 8.75e-7 Intelligence (multi-trait analysis); TGCT cis rs10193935 1.000 rs10173107 chr2:42420302 A/T cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg11905131 chr22:24372483 LOC391322 -0.89 -10.25 -0.68 3.1e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs111803315 1.000 rs111489600 chr14:59993021 G/A cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2228479 0.764 rs7191836 chr16:89961597 T/C cg06558623 chr16:89946397 TCF25 0.5 6.04 0.48 1.68e-8 Skin colour saturation; TGCT cis rs4642101 0.662 rs9840766 chr3:12821870 G/A cg05775895 chr3:12838266 CAND2 0.89 9.51 0.65 1.94e-16 QRS complex (12-leadsum); TGCT cis rs13202913 0.518 rs13205543 chr6:151813779 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.72 -4.46 -0.37 1.78e-5 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7226408 0.842 rs11660592 chr18:34333952 A/G cg06757138 chr18:34340585 FHOD3 0.29 4.95 0.41 2.4e-6 Obesity-related traits; TGCT cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg08392591 chr16:89556376 ANKRD11 0.64 6.12 0.48 1.14e-8 Multiple myeloma (IgH translocation); TGCT cis rs2657888 0.965 rs67036743 chr12:56948786 C/A cg23002907 chr12:56915593 RBMS2 -0.45 -5.77 -0.46 5.87e-8 Adiponectin levels; TGCT cis rs7824557 0.518 rs11250094 chr8:10802001 G/C cg27411982 chr8:10470053 RP1L1 -0.24 -5.04 -0.41 1.62e-6 Retinal vascular caliber; TGCT cis rs7772486 0.719 rs7753770 chr6:146066161 G/A cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6840360 0.598 rs11944921 chr4:152731109 A/G cg22705602 chr4:152727874 NA 0.27 4.89 0.4 3.08e-6 Intelligence (multi-trait analysis); TGCT cis rs739401 0.611 rs2301140 chr11:3022629 C/T cg05729581 chr11:3078854 CARS -0.53 -5.04 -0.41 1.61e-6 Longevity; TGCT cis rs61990749 0.597 rs1477262 chr14:78226653 G/A cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs11249608 0.548 rs35568336 chr5:178451854 A/G cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs67478160 0.634 rs2024669 chr14:104275602 G/C cg01849466 chr14:104193079 ZFYVE21 -0.17 -4.44 -0.37 2e-5 Schizophrenia; TGCT cis rs7786808 0.536 rs4909210 chr7:158194376 T/C cg01191920 chr7:158217561 PTPRN2 -0.36 -5.55 -0.45 1.63e-7 Obesity-related traits; TGCT cis rs61935443 0.666 rs11107780 chr12:95299142 G/A cg21533806 chr12:95267307 NA 0.58 4.85 0.4 3.7e-6 Schizophrenia; TGCT cis rs4727027 0.899 rs7791496 chr7:148863674 C/G cg23583168 chr7:148888333 NA -0.76 -10.09 -0.67 7.46e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs909002 0.849 rs6663012 chr1:32091779 T/G cg13919466 chr1:32135498 COL16A1 -0.32 -4.46 -0.37 1.82e-5 Intelligence (multi-trait analysis); TGCT cis rs1577917 1.000 rs4707239 chr6:86610717 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs2032447 0.933 rs1540275 chr6:26036476 T/C cg03264133 chr6:25882463 NA -0.65 -5.98 -0.47 2.26e-8 Intelligence (multi-trait analysis); TGCT cis rs875971 0.737 rs7803424 chr7:65880605 T/C cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs2243480 0.522 rs12698511 chr7:65474919 G/T cg07424592 chr7:64974309 NA 1.51 8.49 0.61 5.38e-14 Diabetic kidney disease; TGCT cis rs7246657 0.525 rs10401417 chr19:37467540 C/T cg18154014 chr19:37997991 ZNF793 0.73 4.58 0.38 1.11e-5 Coronary artery calcification; TGCT cis rs6901004 0.685 rs354550 chr6:111546484 G/A cg15721981 chr6:111408429 SLC16A10 -0.53 -4.58 -0.38 1.11e-5 Blood metabolite levels; TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs10782582 0.609 rs79835994 chr1:76287508 G/T cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs7267979 0.966 rs6037103 chr20:25369095 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6723226 0.732 rs390480 chr2:32510072 A/C cg02381751 chr2:32503542 YIPF4 -0.51 -5.3 -0.43 5.23e-7 Intelligence (multi-trait analysis); TGCT cis rs554111 0.634 rs12026318 chr1:21316623 T/C cg01072550 chr1:21505969 NA 0.36 5.43 0.44 2.9e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs2243480 1.000 rs313803 chr7:65514731 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs3733585 0.673 rs7376948 chr4:9954708 G/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.48 -0.5 1.93e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.830 rs11097605 chr4:98985167 T/C cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7954584 0.567 rs10840632 chr12:122375460 C/T cg13699009 chr12:122356056 WDR66 0.29 5.64 0.45 1.09e-7 Mean corpuscular volume; TGCT cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg02187348 chr16:89574699 SPG7 0.64 6.75 0.52 5.08e-10 Multiple myeloma (IgH translocation); TGCT cis rs7772486 0.754 rs6922507 chr6:146250155 A/T cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.56 -5.5 -0.44 2.1e-7 Electroencephalogram traits; TGCT cis rs2455799 0.613 rs1532767 chr3:15733600 A/T cg16303742 chr3:15540471 COLQ -0.25 -4.57 -0.38 1.15e-5 Mean platelet volume; TGCT cis rs1784581 0.855 rs1790002 chr6:162384397 G/T cg17173639 chr6:162384350 PARK2 -0.5 -9.31 -0.64 6.05e-16 Itch intensity from mosquito bite; TGCT cis rs12898370 0.561 rs8028830 chr15:77508046 A/G cg27398640 chr15:77910606 LINGO1 -0.33 -4.58 -0.38 1.12e-5 Risky sexual behaviors (alcohol dependence interaction); TGCT cis rs9914988 0.559 rs1109024 chr17:27189971 C/T cg20469991 chr17:27169893 C17orf63 0.69 5.06 0.41 1.5e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1894292 0.505 rs35233345 chr4:74362387 G/A cg05868023 chr4:75230803 EREG 0.53 4.52 0.38 1.43e-5 Prostate cancer; TGCT cis rs10089 1.000 rs4835941 chr5:127430905 C/T cg19767477 chr5:127420684 SLC12A2 -0.43 -4.52 -0.38 1.43e-5 Ileal carcinoids; TGCT cis rs1669338 0.588 rs3846135 chr3:3195574 C/T cg16797762 chr3:3221439 CRBN -0.89 -5.74 -0.46 6.95e-8 White matter integrity; TGCT trans rs1908814 0.516 rs7833079 chr8:11792129 A/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs116095464 0.558 rs2288459 chr5:231143 T/C cg22857025 chr5:266934 NA -0.33 -6.6 -0.51 1.1e-9 Breast cancer; TGCT cis rs739496 0.843 rs4766462 chr12:111871141 A/T cg10833066 chr12:111807467 FAM109A 0.36 5.51 0.44 2.01e-7 Platelet count; TGCT cis rs1538970 0.781 rs10890330 chr1:45920406 G/A cg05343316 chr1:45956843 TESK2 0.86 6.87 0.53 2.7e-10 Platelet count; TGCT trans rs66573146 1.000 rs56350643 chr4:7017591 G/A cg07817883 chr1:32538562 TMEM39B 1.69 8.36 0.6 1.1e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs597539 0.652 rs667989 chr11:68685776 T/A cg21963583 chr11:68658836 MRPL21 0.34 5.66 0.45 9.96e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs17685 0.753 rs2302435 chr7:75676987 G/A cg19862616 chr7:65841803 NCRNA00174 -0.5 -8.42 -0.6 7.75e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs5769707 0.609 rs2071890 chr22:50001291 G/A cg05373962 chr22:49881684 NA -0.31 -5.25 -0.43 6.36e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs36051895 0.695 rs1327494 chr9:4999303 A/G cg02405213 chr9:5042618 JAK2 -0.73 -9.46 -0.65 2.54e-16 Pediatric autoimmune diseases; TGCT cis rs7917772 0.636 rs10786708 chr10:104526245 C/T cg05855489 chr10:104503620 C10orf26 -0.65 -5.33 -0.43 4.54e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs709400 1.000 rs56660916 chr14:104126137 G/T cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs273218 0.573 rs11742692 chr5:53343576 C/T ch.5.1024479R chr5:53302184 ARL15 -0.71 -5.56 -0.45 1.55e-7 Migraine; TGCT cis rs62064224 0.589 rs2344976 chr17:30685935 T/C cg18200150 chr17:30822561 MYO1D 0.39 4.76 0.39 5.35e-6 Schizophrenia; TGCT cis rs3774830 0.714 rs73212742 chr4:5464915 A/G cg26943120 chr4:5472116 STK32B 0.22 4.82 0.4 4.15e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7647973 0.667 rs6446286 chr3:49681704 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs709400 0.628 rs7150317 chr14:103921691 C/G cg26031613 chr14:104095156 KLC1 0.84 9.43 0.65 2.98e-16 Body mass index; TGCT cis rs6095298 0.595 rs8124687 chr20:47453776 T/C cg12307787 chr20:48099359 KCNB1 0.42 4.51 0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs7959452 0.570 rs10878964 chr12:69720691 T/G cg11871910 chr12:69753446 YEATS4 0.63 6.42 0.5 2.57e-9 Blood protein levels; TGCT cis rs9486715 0.867 rs9384602 chr6:96919561 G/A cg18709589 chr6:96969512 KIAA0776 0.82 8.02 0.58 6.9e-13 Headache; TGCT cis rs2302045 1.000 rs78797111 chr2:242056048 T/C cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg02725872 chr8:58115012 NA -0.39 -5.25 -0.43 6.44e-7 Developmental language disorder (linguistic errors); TGCT cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg10802521 chr3:52805072 NEK4 -0.72 -8.83 -0.62 8.28e-15 Bipolar disorder; TGCT trans rs10203711 0.966 rs6713626 chr2:239566896 C/T cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs11031096 0.542 rs10742200 chr11:3989521 A/T cg18678763 chr11:4115507 RRM1 -0.42 -5.14 -0.42 1.04e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6964587 1.000 rs10228800 chr7:91610111 T/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs4730250 0.707 rs257377 chr7:106801088 G/T cg02696742 chr7:106810147 HBP1 -0.71 -5.89 -0.47 3.42e-8 Osteoarthritis; TGCT cis rs1799949 0.965 rs8067269 chr17:41235799 C/T cg05368731 chr17:41323189 NBR1 1.0 10.83 0.7 1.18e-19 Menopause (age at onset); TGCT cis rs4711350 0.765 rs943476 chr6:33750086 A/G cg18005901 chr6:33739558 LEMD2 -0.55 -6.02 -0.48 1.85e-8 Schizophrenia; TGCT cis rs7954584 0.567 rs11612028 chr12:122387872 C/G cg13699009 chr12:122356056 WDR66 0.29 5.7 0.46 8.3e-8 Mean corpuscular volume; TGCT cis rs938554 0.657 rs7679724 chr4:9985376 G/T cg11266682 chr4:10021025 SLC2A9 0.47 4.76 0.39 5.19e-6 Blood metabolite levels; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.51 5.4 0.44 3.28e-7 Lymphocyte counts; TGCT cis rs10876993 0.928 rs1678530 chr12:58054076 A/C cg15848620 chr12:58087721 OS9 -0.73 -5.94 -0.47 2.74e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs11190604 1.000 rs3750720 chr10:102248884 C/T cg23241863 chr10:102295624 HIF1AN 0.59 4.45 0.37 1.92e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7412746 0.658 rs4970986 chr1:150907955 A/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs210152 0.541 rs36003672 chr6:33457816 T/A cg16739976 chr6:34101401 GRM4 0.58 4.75 0.39 5.47e-6 Schizophrenia; TGCT cis rs6570726 0.935 rs391524 chr6:145823844 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10057188 0.545 rs10069173 chr5:77929023 A/C cg17456851 chr5:78090622 ARSB 0.28 4.53 0.38 1.36e-5 Pulse pressure; TGCT cis rs17253792 0.558 rs10083353 chr14:56066370 G/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs11785400 0.928 rs750529 chr8:143744877 G/C cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs35146811 0.700 rs7788301 chr7:99782753 C/G cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs1505368 0.543 rs13413590 chr2:213292329 C/T cg20637307 chr2:213403960 ERBB4 0.53 4.99 0.41 2.02e-6 Symmetrical dimethylarginine levels; TGCT cis rs7607369 0.580 rs7568196 chr2:219652373 G/A cg02176678 chr2:219576539 TTLL4 -0.44 -5.46 -0.44 2.54e-7 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs56399783 0.901 rs73049380 chr7:2832845 C/T cg19731401 chr7:2775893 GNA12 0.37 4.89 0.4 3.12e-6 Childhood ear infection; TGCT cis rs4383453 0.539 rs4678020 chr3:123102353 C/T cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs4727027 0.933 rs6955564 chr7:148866173 A/G cg23583168 chr7:148888333 NA -0.74 -9.82 -0.66 3.47e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs13168506 0.518 rs6883838 chr5:135543677 A/G cg07158503 chr5:135415693 NA -0.42 -4.68 -0.39 7.24e-6 Stroke; TGCT cis rs10791323 0.572 rs10750551 chr11:133737462 G/A cg15485101 chr11:133734466 NA 0.42 6.12 0.48 1.14e-8 Childhood ear infection; TGCT cis rs11031096 0.678 rs11031220 chr11:4197638 G/A cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs782590 0.967 rs10496050 chr2:55806313 C/T cg03859395 chr2:55845619 SMEK2 0.92 11.39 0.72 5.08e-21 Metabolic syndrome; TGCT cis rs67478160 0.654 rs11628240 chr14:104218135 A/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs7044106 1.000 rs7044106 chr9:123494062 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.52 4.65 0.39 8.42e-6 Hip circumference adjusted for BMI; TGCT cis rs7909074 1.000 rs4481983 chr10:45400428 G/T cg05187965 chr10:45406764 TMEM72 -0.24 -5.02 -0.41 1.73e-6 Mean corpuscular volume; TGCT cis rs79976124 0.837 rs10944858 chr6:66646039 G/A cg07460842 chr6:66804631 NA 0.57 5.22 0.42 7.44e-7 Type 2 diabetes; TGCT cis rs5769765 0.773 rs9616206 chr22:50310847 G/T cg15316289 chr22:50310904 ALG12;CRELD2 0.44 6.19 0.49 8.22e-9 Schizophrenia; TGCT cis rs929354 0.713 rs6946660 chr7:156948648 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs7843479 0.506 rs7818430 chr8:21798429 C/T cg17168535 chr8:21777572 XPO7 0.81 8.33 0.6 1.28e-13 Mean corpuscular volume; TGCT cis rs8177253 0.965 rs4854760 chr3:133498741 C/T cg08048268 chr3:133502702 NA 0.65 9.82 0.66 3.47e-17 Iron status biomarkers; TGCT cis rs7584330 0.910 rs880932 chr2:238396963 A/G cg14458575 chr2:238380390 NA 0.49 6.96 0.53 1.75e-10 Prostate cancer; TGCT cis rs1355223 0.583 rs1553757 chr11:34867089 G/A cg11058730 chr11:34937778 PDHX;APIP 0.75 8.13 0.59 3.8e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs4148883 0.675 rs11724783 chr4:100099688 C/A cg12011299 chr4:100065546 ADH4 0.39 5.85 0.47 4.03e-8 Alcohol dependence; TGCT cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs1814175 0.817 rs11040651 chr11:49938395 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs4478858 0.684 rs12135540 chr1:31764693 G/A cg00250761 chr1:31883323 NA -0.25 -4.48 -0.37 1.64e-5 Alcohol dependence; TGCT cis rs986417 0.748 rs4899011 chr14:60986698 A/G cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs9467711 0.659 rs35555795 chr6:26509382 C/T cg16898833 chr6:26189333 HIST1H4D 1.24 5.61 0.45 1.26e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9467711 0.606 rs9379871 chr6:26375854 C/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs17102423 0.768 rs8005829 chr14:65576165 C/T cg11161011 chr14:65562177 MAX 0.43 5.68 0.45 9.04e-8 Obesity-related traits; TGCT cis rs2153535 0.580 rs7769020 chr6:8457724 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2760061 0.626 rs594916 chr1:228133544 C/A cg02753203 chr1:228287806 NA -0.34 -6.56 -0.51 1.33e-9 Diastolic blood pressure; TGCT cis rs6912958 0.781 rs4707379 chr6:88310623 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.57 -0.38 1.16e-5 Monocyte percentage of white cells; TGCT cis rs7772486 0.754 rs9399561 chr6:145955687 C/G cg05347473 chr6:146136440 FBXO30 0.53 4.97 0.41 2.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 5.92 0.47 2.92e-8 Alzheimer's disease; TGCT cis rs514406 0.861 rs551435 chr1:53260537 G/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs12220898 0.749 rs7911514 chr10:50485523 T/G cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs4730250 0.670 rs9641380 chr7:106868151 C/G cg02696742 chr7:106810147 HBP1 -0.71 -5.76 -0.46 6.26e-8 Osteoarthritis; TGCT cis rs13217239 0.646 rs4583981 chr6:26992023 G/T cg05738196 chr6:26577821 NA 0.49 4.78 0.39 4.97e-6 Schizophrenia; TGCT cis rs35883536 0.626 rs7536054 chr1:101047849 A/G cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT trans rs2243480 1.000 rs2707844 chr7:66059509 G/A cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs6121246 0.567 rs6060297 chr20:30198560 A/G cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs12530845 0.943 rs78188670 chr7:135335163 T/C cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs1008375 0.966 rs6813375 chr4:17649499 T/G cg10189774 chr4:17578691 LAP3 0.6 5.29 0.43 5.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9399135 0.816 rs4134030 chr6:135354094 G/T cg24558204 chr6:135376177 HBS1L 0.48 4.77 0.39 5.14e-6 Red blood cell count; TGCT cis rs4642101 0.561 rs7641959 chr3:12810755 G/C cg04715183 chr3:11886989 C3orf31 -0.17 -4.44 -0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs4862750 0.624 rs34414639 chr4:187873417 C/A cg03452623 chr4:187889614 NA -0.36 -5.34 -0.43 4.3e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs950169 0.544 rs62021193 chr15:85170583 C/G cg11189052 chr15:85197271 WDR73 0.75 6.25 0.49 5.98e-9 Schizophrenia; TGCT trans rs10506458 0.915 rs998505 chr12:63400018 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs1153858 0.887 rs7171163 chr15:45636395 A/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs1371867 0.810 rs2919470 chr8:101233301 C/A cg06002616 chr8:101225028 SPAG1 0.52 5.91 0.47 3.1e-8 Atrioventricular conduction; TGCT cis rs2742417 1.000 rs2742406 chr3:45760600 C/T cg04837898 chr3:45731254 SACM1L -0.51 -5.27 -0.43 5.85e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs3806843 1.000 rs1548699 chr5:140164918 T/C cg19875535 chr5:140030758 IK 0.37 6.17 0.48 8.88e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2204008 0.713 rs2320522 chr12:38251438 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs17473412 1.000 rs74455127 chr5:122746164 T/A cg15125798 chr5:122621645 NA -0.6 -5.38 -0.44 3.52e-7 Total body bone mineral density; TGCT cis rs769267 0.930 rs1054284 chr19:19616953 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.65 5.44 0.44 2.74e-7 Tonsillectomy; TGCT cis rs11690935 1.000 rs6721680 chr2:172543913 G/T cg13550731 chr2:172543902 DYNC1I2 1.2 12.95 0.76 8.62e-25 Schizophrenia; TGCT cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs853679 0.517 rs3823180 chr6:28061744 G/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs6912958 0.535 rs1753153 chr6:88032834 T/G cg12350822 chr6:88032061 C6orf162;GJB7 0.43 5.57 0.45 1.51e-7 Monocyte percentage of white cells; TGCT cis rs6586111 1.000 rs6586107 chr10:82373516 C/T cg03086067 chr10:82368399 SH2D4B 0.26 5.23 0.43 6.93e-7 Capecitabine sensitivity; TGCT cis rs1008375 0.966 rs28441502 chr4:17598384 G/A cg16339924 chr4:17578868 LAP3 0.74 6.32 0.49 4.28e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs55962025 0.804 rs2269499 chr4:3239702 C/T cg06533319 chr4:3265114 C4orf44 0.24 4.86 0.4 3.48e-6 Parental longevity (mother's age at death); TGCT trans rs1116255 0.725 rs9569158 chr13:55554192 A/G cg27012908 chr16:22345154 POLR3E 0.52 6.93 0.53 2.05e-10 Post-traumatic stress disorder; TGCT cis rs7809950 0.723 rs62483633 chr7:106876644 T/G cg23024343 chr7:107201750 COG5 -0.43 -6.11 -0.48 1.19e-8 Coronary artery disease; TGCT cis rs861020 0.771 rs654470 chr1:210014093 A/T cg05527609 chr1:210001259 C1orf107 1.05 9.38 0.64 4e-16 Orofacial clefts; TGCT cis rs35306767 0.714 rs10508206 chr10:1075777 A/C cg20503657 chr10:835505 NA 0.51 5.79 0.46 5.46e-8 Eosinophil percentage of granulocytes; TGCT cis rs7000551 0.663 rs11778831 chr8:22335088 C/T cg12081754 chr8:22256438 SLC39A14 0.3 4.97 0.41 2.14e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6450176 1.000 rs3776702 chr5:53305419 G/A ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs11792861 0.781 rs17729408 chr9:111740860 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.5 -4.72 -0.39 6.2e-6 Menarche (age at onset); TGCT cis rs6500602 0.727 rs55939215 chr16:4541390 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.52 0.44 1.86e-7 Schizophrenia; TGCT cis rs7208859 0.623 rs9914499 chr17:29107588 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10501293 0.709 rs10768911 chr11:43028688 G/T cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.14e-9 Cognitive performance; TGCT cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs8013055 0.898 rs8004007 chr14:105971435 G/C cg25008857 chr14:105974488 NA 0.28 4.65 0.39 8.41e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs12220238 0.915 rs2894235 chr10:76082945 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.28 0.49 5.18e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg03517284 chr6:25882590 NA -0.65 -6.72 -0.52 5.87e-10 Blood metabolite levels; TGCT cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs11031096 0.621 rs11031159 chr11:4179695 T/G cg18678763 chr11:4115507 RRM1 -0.43 -5.51 -0.44 1.99e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs651907 0.557 rs3094296 chr3:101400167 A/G cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.6 -0.51 1.09e-9 Colorectal cancer; TGCT cis rs7674212 0.539 rs6850461 chr4:104120041 C/T cg16532752 chr4:104119610 CENPE -0.6 -5.46 -0.44 2.51e-7 Type 2 diabetes; TGCT cis rs10746514 1.000 rs9724948 chr1:232248244 C/T cg09506761 chr1:232265262 NA 0.5 5.11 0.42 1.17e-6 Response to statin therapy; TGCT cis rs875971 1.000 rs778710 chr7:65854834 T/C cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg25703541 chr22:24373054 LOC391322 -0.82 -8.62 -0.61 2.61e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1215050 0.791 rs783959 chr4:98893476 C/T cg17366294 chr4:99064904 C4orf37 -0.55 -5.92 -0.47 2.97e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs240764 0.658 rs1336244 chr6:101197953 C/T cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs2463822 1.000 rs115395195 chr11:62100353 G/A cg23876832 chr11:62092739 NA -0.65 -4.56 -0.38 1.19e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7572733 0.515 rs893808 chr2:198860837 C/G cg00792783 chr2:198669748 PLCL1 0.57 5.1 0.42 1.24e-6 Dermatomyositis; TGCT cis rs9913156 0.793 rs8074545 chr17:4567337 C/G cg23387401 chr17:4582204 PELP1 -0.31 -4.63 -0.38 8.97e-6 Lymphocyte counts; TGCT trans rs3780486 0.713 rs3780489 chr9:33129844 G/T cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs9527 0.590 rs7906754 chr10:104782557 T/C cg04362960 chr10:104952993 NT5C2 0.65 5.54 0.45 1.73e-7 Arsenic metabolism; TGCT cis rs1008375 0.866 rs12233712 chr4:17570063 T/A cg16339924 chr4:17578868 LAP3 0.75 6.62 0.51 9.69e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11577318 0.579 rs11583205 chr1:26684141 C/A cg14210634 chr1:25870291 LDLRAP1 0.53 4.62 0.38 9.59e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9858542 0.953 rs9853683 chr3:49512588 A/G cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs4786125 0.920 rs6500852 chr16:6896649 A/G cg03623568 chr16:6915990 A2BP1 -0.35 -4.76 -0.39 5.25e-6 Heart rate variability traits (SDNN); TGCT cis rs7267979 0.933 rs2387887 chr20:25427081 G/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13064411 0.660 rs3829889 chr3:113015464 G/A cg18753928 chr3:113234510 CCDC52 -0.71 -5.09 -0.42 1.29e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs28595532 0.920 rs116634064 chr4:119736514 C/T cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs6582630 0.555 rs11181684 chr12:38388000 T/C cg26384229 chr12:38710491 ALG10B 0.8 6.88 0.53 2.6200000000000003e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs3820068 0.603 rs1980607 chr1:15975237 A/G cg05660106 chr1:15850417 CASP9 0.82 8.06 0.59 5.53e-13 Systolic blood pressure; TGCT cis rs9467773 0.526 rs12199613 chr6:26367218 C/T cg15659132 chr6:26577336 NA -0.5 -5.05 -0.41 1.53e-6 Intelligence (multi-trait analysis); TGCT cis rs6901250 0.632 rs1853080 chr6:117196157 T/C cg12892004 chr6:117198278 RFX6 -0.45 -5.68 -0.45 9e-8 C-reactive protein levels; TGCT cis rs67460515 0.892 rs34896809 chr3:161059804 C/T cg03342759 chr3:160939853 NMD3 -0.54 -5.9 -0.47 3.25e-8 Parkinson's disease; TGCT cis rs7107174 0.892 rs7115850 chr11:78045071 C/G cg12700464 chr11:78128424 GAB2 -0.61 -4.48 -0.37 1.67e-5 Testicular germ cell tumor; TGCT cis rs7819412 0.594 rs60921132 chr8:10964969 T/A cg12940923 chr8:10282607 MSRA -0.19 -4.61 -0.38 1e-5 Triglycerides; TGCT cis rs2115630 0.645 rs3825878 chr15:85174755 C/T cg11189052 chr15:85197271 WDR73 -0.76 -7.38 -0.55 1.99e-11 P wave terminal force; TGCT cis rs9916302 0.768 rs62077464 chr17:37656056 C/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.87 -0.4 3.4e-6 Glomerular filtration rate (creatinine); TGCT cis rs57590327 0.679 rs17018967 chr3:81512209 G/A cg07356753 chr3:81810745 GBE1 -0.53 -4.44 -0.37 1.97e-5 Extraversion; TGCT cis rs769267 0.965 rs6511026 chr19:19391402 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs6901004 0.803 rs1150083 chr6:111510767 C/T cg15721981 chr6:111408429 SLC16A10 -0.53 -4.64 -0.38 8.82e-6 Blood metabolite levels; TGCT cis rs12497850 0.931 rs11920534 chr3:48937761 G/T cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs208520 0.955 rs208538 chr6:66964492 C/G cg07460842 chr6:66804631 NA -0.82 -7.44 -0.56 1.46e-11 Exhaled nitric oxide output; TGCT cis rs2749592 0.588 rs2504144 chr10:38383525 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -7.02 -0.53 1.27e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs992157 0.560 rs10932763 chr2:219085863 G/C cg00012203 chr2:219082015 ARPC2 -0.81 -9.36 -0.64 4.37e-16 Colorectal cancer; TGCT cis rs10838634 1.000 rs11822959 chr11:46806553 C/T cg18332754 chr11:46939436 LRP4 0.84 4.66 0.39 8.02e-6 Schizophrenia; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs4372836 0.518 rs12472549 chr2:28992004 T/C cg09522027 chr2:28974177 PPP1CB -0.73 -7.07 -0.54 9.78e-11 Body mass index; TGCT cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9291683 0.530 rs6449196 chr4:9973660 C/T cg11266682 chr4:10021025 SLC2A9 -0.62 -8.62 -0.61 2.56e-14 Bone mineral density; TGCT cis rs617791 0.678 rs551659 chr11:65749645 C/T cg17985854 chr11:65770987 BANF1;EIF1AD 0.23 4.87 0.4 3.28e-6 Breast cancer; TGCT cis rs763121 0.853 rs2281020 chr22:39064406 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs6815814 0.861 rs1135430 chr4:38789361 T/C cg02016764 chr4:38805732 TLR1 -0.27 -4.51 -0.38 1.5e-5 Breast cancer; TGCT cis rs9560113 0.764 rs1177401 chr13:112173067 T/C cg14154082 chr13:112174009 NA -0.34 -4.47 -0.37 1.73e-5 Menarche (age at onset); TGCT cis rs7267979 1.000 rs2257982 chr20:25269630 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs36051895 0.589 rs6476948 chr9:5204404 C/T cg02405213 chr9:5042618 JAK2 -0.74 -9.28 -0.64 7.07e-16 Pediatric autoimmune diseases; TGCT cis rs4372836 1.000 rs6710959 chr2:28958603 C/T cg09522027 chr2:28974177 PPP1CB -0.59 -5.15 -0.42 1e-6 Body mass index; TGCT cis rs6684514 1.000 rs12023704 chr1:156294149 C/A cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs813218 0.584 rs11711935 chr3:99808804 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.44 -4.98 -0.41 2.06e-6 Orofacial clefts; TGCT cis rs9467773 1.000 rs1056667 chr6:26510564 T/C cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs882732 0.576 rs12895360 chr14:95038922 T/C cg24754598 chr14:95966488 NA 0.24 4.54 0.38 1.31e-5 Blood protein levels; TGCT cis rs910187 1.000 rs6063085 chr20:45840459 A/C cg27589058 chr20:45804311 EYA2 -0.31 -5.66 -0.45 9.88e-8 Migraine; TGCT cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.97e-6 Initial pursuit acceleration; TGCT cis rs6722750 0.933 rs4671553 chr2:64408476 A/T cg22352474 chr2:64371530 PELI1 -0.58 -5.14 -0.42 1.05e-6 Neuroticism; TGCT cis rs6121246 0.529 rs6060171 chr20:30183269 C/T cg13852791 chr20:30311386 BCL2L1 0.69 4.53 0.38 1.36e-5 Mean corpuscular hemoglobin; TGCT cis rs3093024 0.967 rs1571878 chr6:167540842 C/T cg07741184 chr6:167504864 NA -0.24 -4.85 -0.4 3.6e-6 Rheumatoid arthritis; TGCT cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg01017244 chr2:74357527 NA 0.42 5.82 0.46 4.64e-8 Gestational age at birth (maternal effect); TGCT cis rs4455778 0.802 rs35570114 chr7:49094318 C/T cg26309511 chr7:48887640 NA 0.49 5.49 0.44 2.21e-7 Lung cancer in never smokers; TGCT cis rs612683 0.599 rs2809823 chr1:101003762 C/A cg14855972 chr1:101004472 GPR88 0.24 4.76 0.39 5.28e-6 Breast cancer; TGCT cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7611238 0.560 rs62288367 chr3:195118322 T/C cg27323046 chr3:195102265 ACAP2 0.39 5.17 0.42 8.93e-7 Body mass index; TGCT cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg18230493 chr5:56204884 C5orf35 -0.69 -6.01 -0.48 1.9e-8 Initial pursuit acceleration; TGCT cis rs7611238 0.560 rs9817672 chr3:195141827 T/C cg27323046 chr3:195102265 ACAP2 0.37 4.97 0.41 2.17e-6 Body mass index; TGCT cis rs7582180 0.629 rs6757754 chr2:100951273 C/T cg14675211 chr2:100938903 LONRF2 -0.53 -5.16 -0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs1205863 1.000 rs1205855 chr6:11942657 A/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs3784262 0.643 rs8030766 chr15:58369209 A/G cg12031962 chr15:58353849 ALDH1A2 0.39 5.68 0.45 9.05e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg13397359 chr6:42928475 GNMT 0.72 6.48 0.5 1.93e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs826838 0.935 rs1719855 chr12:39127242 C/T cg13010199 chr12:38710504 ALG10B -0.63 -5.04 -0.41 1.6e-6 Heart rate; TGCT cis rs6674176 0.597 rs2352990 chr1:44393276 T/A cg13606994 chr1:44402422 ARTN -0.51 -5.42 -0.44 2.94e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7914558 1.000 rs7899084 chr10:104872547 A/T cg04362960 chr10:104952993 NT5C2 0.63 5.64 0.45 1.07e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs317689 0.918 rs610192 chr12:69739941 T/C cg11871910 chr12:69753446 YEATS4 0.6 5.08 0.41 1.36e-6 Response to diuretic therapy; TGCT cis rs4727027 0.625 rs75129390 chr7:148846775 T/A cg23583168 chr7:148888333 NA -0.74 -9.12 -0.63 1.72e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7917772 0.503 rs1409310 chr10:104282265 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8002180 1.000 rs8002180 chr13:95922765 T/C cg24476569 chr13:95954382 ABCC4 0.41 5.09 0.42 1.31e-6 Blood metabolite levels; TGCT cis rs9914544 0.545 rs9915343 chr17:18766494 A/G cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs425277 0.606 rs451061 chr1:2075068 C/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.34 -4.85 -0.4 3.66e-6 Height; TGCT cis rs1008375 0.932 rs7677212 chr4:17675932 A/G cg16339924 chr4:17578868 LAP3 -0.59 -4.82 -0.4 4.05e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9486715 0.867 rs9373887 chr6:96957004 C/T cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs3772130 0.540 rs57791671 chr3:121608433 T/A cg20356878 chr3:121714668 ILDR1 0.39 4.85 0.4 3.64e-6 Cognitive performance; TGCT cis rs1692580 0.774 rs10797416 chr1:2182342 T/C cg21194808 chr1:2205498 SKI 0.29 5.5 0.44 2.06e-7 Coronary artery disease; TGCT cis rs7586879 0.639 rs6749170 chr2:25110962 A/G cg01884057 chr2:25150051 NA 0.34 6.5 0.5 1.8e-9 Body mass index; TGCT cis rs61990749 0.544 rs1477259 chr14:78256138 C/G cg02301378 chr14:78227641 SNW1;C14orf178 0.61 4.52 0.38 1.43e-5 Fibroblast growth factor basic levels; TGCT cis rs6088580 0.634 rs4911421 chr20:32998948 T/C cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs2070433 0.615 rs2073379 chr21:47863025 C/T cg12379764 chr21:47803548 PCNT 0.55 4.6 0.38 1.04e-5 Lymphocyte counts; TGCT cis rs7659604 0.689 rs4283687 chr4:122663460 A/G cg06713675 chr4:122721982 EXOSC9 -0.45 -5.11 -0.42 1.19e-6 Type 2 diabetes; TGCT cis rs11648796 0.757 rs6600231 chr16:766485 A/G cg27144592 chr16:783916 NARFL -0.36 -5.04 -0.41 1.58e-6 Height; TGCT cis rs240764 0.764 rs6910391 chr6:100925774 T/C cg21058520 chr6:100914733 NA 0.38 4.6 0.38 1.04e-5 Neuroticism; TGCT cis rs6831352 0.879 rs56272995 chr4:100060882 A/G cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs10504229 0.871 rs60342323 chr8:58154899 T/C cg24829409 chr8:58192753 C8orf71 -0.54 -4.84 -0.4 3.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs4280164 0.551 rs2295300 chr14:24805117 C/T cg07162820 chr14:24837146 NFATC4 0.36 4.6 0.38 1.05e-5 Parent of origin effect on language impairment (paternal); TGCT cis rs595982 0.661 rs606400 chr19:49371498 T/C cg21252483 chr19:49399788 TULP2 -0.26 -4.5 -0.37 1.53e-5 Red cell distribution width; TGCT cis rs968567 0.705 rs174573 chr11:61600327 G/A cg19610905 chr11:61596333 FADS2 -0.99 -9.08 -0.63 2.15e-15 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs4925386 1.000 rs2151512 chr20:60913495 T/C cg24112000 chr20:60950667 NA 0.33 4.57 0.38 1.17e-5 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs6430585 0.528 rs309172 chr2:136674028 A/G cg07169764 chr2:136633963 MCM6 1.21 11.7 0.72 9.03e-22 Corneal structure; TGCT cis rs62344088 0.590 rs2115276 chr5:169829 C/G cg10601043 chr5:1076365 SLC12A7 0.58 4.74 0.39 5.71e-6 Asthma (childhood onset); TGCT cis rs6087990 0.735 rs2065576 chr20:31389009 C/T cg13636640 chr20:31349939 DNMT3B 0.97 12.84 0.76 1.63e-24 Ulcerative colitis; TGCT cis rs1401999 0.966 rs2313216 chr3:183637251 C/T cg01324343 chr3:183735012 ABCC5 0.81 11.09 0.71 2.81e-20 Anterior chamber depth; TGCT cis rs9303401 0.659 rs34556735 chr17:56694447 A/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs12142240 0.660 rs72885163 chr1:46807117 C/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs10876993 0.928 rs774890 chr12:58068388 C/T cg15848620 chr12:58087721 OS9 -0.72 -5.91 -0.47 3.12e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs4665809 1.000 rs12471809 chr2:26307140 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs4253772 0.614 rs11090859 chr22:46687460 T/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 5.22 0.42 7.37e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs7312933 0.558 rs1796384 chr12:42780568 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.57 -5.57 -0.45 1.5e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs11711311 1.000 rs9848993 chr3:113497914 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs7945705 0.875 rs2653616 chr11:8885892 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.48 -5.5 -0.44 2.03e-7 Hemoglobin concentration; TGCT cis rs7666738 0.830 rs4699601 chr4:99034429 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs921968 0.541 rs599973 chr2:219387273 C/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs11785400 1.000 rs9720653 chr8:143731939 T/G cg24634471 chr8:143751801 JRK 0.54 5.85 0.46 4.19e-8 Schizophrenia; TGCT cis rs11122272 0.735 rs2808583 chr1:231512587 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.96e-11 Hemoglobin concentration; TGCT cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.715 rs7586608 chr2:99558017 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.56 -4.74 -0.39 5.73e-6 Chronic sinus infection; TGCT cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg03303774 chr4:1407052 NA 0.29 4.81 0.4 4.24e-6 Obesity-related traits; TGCT cis rs1008375 1.000 rs4698199 chr4:17656738 G/C cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs796364 0.806 rs11679676 chr2:201040981 C/T cg17644776 chr2:200775616 C2orf69 -0.34 -4.8 -0.4 4.49e-6 Schizophrenia; TGCT cis rs1865760 0.566 rs2794720 chr6:26087202 G/C cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs12579753 0.956 rs35278765 chr12:82173126 T/C cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs6912958 0.559 rs445434 chr6:88041849 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.7 7.16 0.54 6.1e-11 Monocyte percentage of white cells; TGCT cis rs10946940 0.965 rs6915266 chr6:27528643 G/A cg10876282 chr6:28092338 ZSCAN16 -0.47 -4.74 -0.39 5.81e-6 Systemic lupus erythematosus; TGCT cis rs7666738 0.519 rs13136069 chr4:98819568 C/T cg05340658 chr4:99064831 C4orf37 0.55 5.96 0.47 2.42e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11122272 0.735 rs2790883 chr1:231532726 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.56 -0.51 1.3e-9 Hemoglobin concentration; TGCT cis rs12142240 0.698 rs41293285 chr1:46808426 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs11031096 0.678 rs61899666 chr11:4178711 C/A cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs11122272 0.735 rs910823 chr1:231498766 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.63 -0.51 9.1e-10 Hemoglobin concentration; TGCT cis rs7209700 0.889 rs11079769 chr17:45349731 A/T cg21624342 chr17:45890973 OSBPL7 0.18 4.99 0.41 1.97e-6 IgG glycosylation; TGCT cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg07636037 chr3:49044803 WDR6 0.86 8.75 0.62 1.33e-14 Menarche (age at onset); TGCT cis rs6770219 0.516 rs59017423 chr3:186133885 C/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.75 4.6 0.38 1.03e-5 Cerebrospinal T-tau levels; TGCT cis rs10540 1.000 rs61876335 chr11:488878 T/C cg03934478 chr11:495069 RNH1 0.36 5.95 0.47 2.54e-8 Body mass index; TGCT cis rs9611565 0.649 rs139559 chr22:42191636 A/G cg13695892 chr22:41940480 POLR3H -0.81 -7.83 -0.58 1.87e-12 Vitiligo; TGCT cis rs12541335 0.536 rs4266653 chr8:22169087 A/G cg07298985 chr8:22133076 PIWIL2 0.32 5.14 0.42 1.03e-6 Hypertriglyceridemia; TGCT cis rs4295623 0.531 rs2898295 chr8:11595969 C/T cg21775007 chr8:11205619 TDH -0.52 -4.9 -0.4 2.97e-6 Morning vs. evening chronotype; TGCT cis rs3847687 0.966 rs3847689 chr12:131525534 T/G cg25772418 chr12:131519998 GPR133 -0.33 -6.1 -0.48 1.26e-8 Longevity; TGCT cis rs10782582 0.586 rs12130324 chr1:76370012 A/G cg10523679 chr1:76189770 ACADM -0.58 -5.26 -0.43 5.99e-7 Daytime sleep phenotypes; TGCT cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg01448562 chr3:133502909 NA -0.26 -5.01 -0.41 1.83e-6 Iron status biomarkers; TGCT cis rs6964587 1.000 rs1859114 chr7:91682848 T/C cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs589249 0.963 rs1395455 chr1:37185190 A/G cg04012535 chr1:37176647 NA 0.35 5.57 0.45 1.52e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs6815814 0.851 rs73236644 chr4:38863193 A/G cg02016764 chr4:38805732 TLR1 -0.37 -5.49 -0.44 2.19e-7 Breast cancer; TGCT cis rs1403694 0.695 rs13317089 chr3:186436217 G/C cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs7246657 0.943 rs13345116 chr19:37847098 A/T cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.3e-7 Coronary artery calcification; TGCT cis rs6546537 0.869 rs35024605 chr2:69820332 A/G cg10773587 chr2:69614142 GFPT1 -0.73 -6.92 -0.53 2.1e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs7666738 0.800 rs13107586 chr4:99028788 G/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7824557 0.592 rs2736280 chr8:11223022 C/A cg21775007 chr8:11205619 TDH 0.66 6.19 0.49 8.04e-9 Retinal vascular caliber; TGCT cis rs1153858 1.000 rs12440038 chr15:45706739 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.67 0.45 9.65e-8 Homoarginine levels; TGCT cis rs2486288 0.656 rs11632777 chr15:45551045 C/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs2120019 1.000 rs12901243 chr15:75374233 C/T cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT cis rs514406 0.825 rs6588441 chr1:53223494 G/A cg25767906 chr1:53392781 SCP2 0.48 5.56 0.45 1.57e-7 Monocyte count; TGCT trans rs6089829 0.962 rs3746747 chr20:61667631 T/C cg13615516 chr5:77269221 NA 0.68 8.55 0.61 3.8e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs910316 1.000 rs10140851 chr14:75512612 G/A cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.32e-6 Height; TGCT cis rs11190604 1.000 rs4919465 chr10:102221703 C/T cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1552244 0.935 rs28815328 chr3:10062227 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.98 0.47 2.25e-8 Alzheimer's disease; TGCT cis rs4819052 0.851 rs2236446 chr21:46678985 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.62 0.38 9.36e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7772486 0.846 rs2892453 chr6:146377717 C/A cg23711669 chr6:146136114 FBXO30 0.85 9.11 0.63 1.76e-15 Lobe attachment (rater-scored or self-reported); TGCT trans rs1005277 0.522 rs289647 chr10:37968278 A/G cg17830980 chr10:43048298 ZNF37B -0.64 -7.29 -0.55 3.11e-11 Extrinsic epigenetic age acceleration; TGCT cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg22663859 chr13:21900854 NA 0.34 4.93 0.4 2.59e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9814567 1.000 rs6806417 chr3:134211446 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 1.07 9.61 0.65 1.14e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4372836 0.964 rs4531886 chr2:28917964 T/C cg09522027 chr2:28974177 PPP1CB 0.57 4.67 0.39 7.61e-6 Body mass index; TGCT cis rs9341808 0.754 rs1015158 chr6:80945745 C/T cg08355045 chr6:80787529 NA 0.29 5.1 0.42 1.23e-6 Sitting height ratio; TGCT cis rs79349575 0.783 rs12453374 chr17:46994846 G/C cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs7809950 0.773 rs9791733 chr7:107041730 T/C cg23024343 chr7:107201750 COG5 -0.48 -6.33 -0.49 4.11e-9 Coronary artery disease; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg15242686 chr22:24348715 GSTTP1 -0.41 -4.96 -0.41 2.25e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg08280861 chr8:58055591 NA 0.36 4.98 0.41 2.07e-6 Developmental language disorder (linguistic errors); TGCT cis rs2742417 0.603 rs2742371 chr3:45782763 G/A cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7394190 0.748 rs11000771 chr10:75524458 T/G cg07699608 chr10:75541558 CHCHD1 0.76 4.77 0.39 5.13e-6 Incident atrial fibrillation; TGCT trans rs916888 0.773 rs199445 chr17:44817408 C/T cg10053473 chr17:62856997 LRRC37A3 -0.46 -6.76 -0.52 4.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs60154123 0.730 rs10863818 chr1:210458007 C/T cg22029157 chr1:209979665 IRF6 0.6 4.46 0.37 1.81e-5 Coronary artery disease; TGCT cis rs9467711 0.516 rs1165184 chr6:25836257 C/G cg03264133 chr6:25882463 NA -0.66 -4.55 -0.38 1.26e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs28595532 1.000 rs115965820 chr4:119586485 G/A cg14228332 chr4:119757509 SEC24D 1.0 5.77 0.46 5.96e-8 Cannabis dependence symptom count; TGCT cis rs3858526 1.000 rs10838909 chr11:5960490 G/A cg05234568 chr11:5960015 NA -0.45 -4.54 -0.38 1.3e-5 DNA methylation (variation); TGCT cis rs9467773 1.000 rs11756120 chr6:26529808 G/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs1949733 0.598 rs55765509 chr4:8532732 T/A cg13073564 chr4:8508604 NA 0.47 4.56 0.38 1.19e-5 Response to antineoplastic agents; TGCT cis rs1005277 0.579 rs2008449 chr10:38414204 A/T cg25427524 chr10:38739819 LOC399744 0.38 7.87 0.58 1.51e-12 Extrinsic epigenetic age acceleration; TGCT cis rs3809566 0.597 rs9806545 chr15:63328490 C/T cg08198488 chr15:63333792 TPM1 -0.34 -5.11 -0.42 1.18e-6 Platelet count; TGCT cis rs1008375 1.000 rs12507142 chr4:17656103 A/G cg18681998 chr4:17616180 MED28 1.02 12.01 0.73 1.65e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6087990 0.735 rs6058891 chr20:31386347 T/C cg13636640 chr20:31349939 DNMT3B 0.95 12.3 0.74 3.25e-23 Ulcerative colitis; TGCT cis rs6993813 0.805 rs4327884 chr8:120019593 A/G cg17171407 chr8:119960777 TNFRSF11B 0.25 4.49 0.37 1.59e-5 Bone mineral density (hip); TGCT trans rs34421088 0.560 rs2248316 chr8:11397073 A/C cg15556689 chr8:8085844 FLJ10661 -0.75 -7.08 -0.54 9.46e-11 Neuroticism; TGCT cis rs3796352 1.000 rs11710707 chr3:52975916 A/G cg15956490 chr3:53032818 SFMBT1 0.61 6.11 0.48 1.17e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2235642 0.893 rs8051295 chr16:1588087 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.3 -5.24 -0.43 6.8e-7 Coronary artery disease; TGCT cis rs9486715 1.000 rs7752277 chr6:97065131 C/T cg06623918 chr6:96969491 KIAA0776 -1.08 -13.59 -0.77 2.61e-26 Headache; TGCT cis rs6933660 0.800 rs963193 chr6:151789355 G/T cg14416726 chr6:151773293 C6orf211;RMND1 0.9 9.63 0.65 1.01e-16 Menarche (age at onset); TGCT cis rs9581857 0.556 rs1885991 chr13:28040470 G/A cg22138327 chr13:27999177 GTF3A 0.73 5.7 0.46 8.09e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2228479 0.850 rs1108063 chr16:89893983 A/G cg06558623 chr16:89946397 TCF25 0.55 4.79 0.4 4.69e-6 Skin colour saturation; TGCT cis rs7552404 1.000 rs11163924 chr1:76132070 A/C cg03433033 chr1:76189801 ACADM -0.83 -10.26 -0.68 3.01e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs739401 0.566 rs7931504 chr11:3026712 C/T cg05729581 chr11:3078854 CARS -0.53 -4.81 -0.4 4.3e-6 Longevity; TGCT cis rs10883723 0.810 rs7093028 chr10:104259417 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6424115 0.964 rs2473375 chr1:24136545 C/T cg15997130 chr1:24165203 NA 0.92 10.78 0.7 1.58e-19 Immature fraction of reticulocytes; TGCT cis rs769267 0.930 rs4808955 chr19:19552413 T/C cg03709012 chr19:19516395 GATAD2A 0.74 6.12 0.48 1.15e-8 Tonsillectomy; TGCT cis rs1538970 0.847 rs781230 chr1:45880751 C/T cg05343316 chr1:45956843 TESK2 -0.73 -5.85 -0.47 4.08e-8 Platelet count; TGCT cis rs12220238 1.000 rs9665468 chr10:75938838 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.92 6.98 0.53 1.61e-10 Soluble interleukin-2 receptor subunit alpha; TGCT trans rs2688608 0.592 rs3849967 chr10:75483366 C/T cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs4654899 0.865 rs12123300 chr1:21323568 T/C cg01072550 chr1:21505969 NA -0.46 -6.95 -0.53 1.88e-10 Superior frontal gyrus grey matter volume; TGCT trans rs7819412 0.806 rs17723229 chr8:10930069 A/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.06 -0.54 1.04e-10 Triglycerides; TGCT cis rs735396 0.770 rs2464196 chr12:121435427 G/A cg02403541 chr12:121454288 C12orf43 0.76 7.54 0.56 8.67e-12 N-glycan levels; TGCT cis rs7226408 0.857 rs11081985 chr18:34682970 A/G cg06757138 chr18:34340585 FHOD3 -0.25 -4.81 -0.4 4.33e-6 Obesity-related traits; TGCT cis rs908922 0.582 rs1856121 chr1:152512169 A/T cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs7944584 0.632 rs11606683 chr11:47302733 C/T cg20307385 chr11:47447363 PSMC3 0.79 7.89 0.58 1.37e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs1153858 0.943 rs4774580 chr15:45652086 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs7666738 0.962 rs11728816 chr4:98951767 C/T cg05340658 chr4:99064831 C4orf37 0.51 5.0 0.41 1.88e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7762018 0.760 rs28660085 chr6:170101996 C/G cg15038512 chr6:170123185 PHF10 0.63 4.76 0.39 5.21e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs3806843 1.000 rs11167609 chr5:140200426 T/G cg19875535 chr5:140030758 IK 0.35 5.86 0.47 3.93e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs782590 0.837 rs782585 chr2:55922930 C/T cg03859395 chr2:55845619 SMEK2 0.83 9.81 0.66 3.69e-17 Metabolic syndrome; TGCT cis rs9653442 0.545 rs10496344 chr2:100764125 C/T cg22139774 chr2:100720529 AFF3 0.37 5.82 0.46 4.82e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2204008 0.549 rs12312109 chr12:38228251 G/T cg26384229 chr12:38710491 ALG10B -0.53 -4.52 -0.38 1.44e-5 Bladder cancer; TGCT cis rs992157 0.798 rs2382818 chr2:219155907 A/T cg00012203 chr2:219082015 ARPC2 -0.77 -7.41 -0.55 1.68e-11 Colorectal cancer; TGCT cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg13393036 chr8:95962371 TP53INP1 0.58 7.86 0.58 1.58e-12 Type 2 diabetes; TGCT cis rs7193541 0.965 rs7199068 chr16:74698263 C/G cg05800356 chr16:74706258 MLKL 0.25 4.48 0.37 1.71e-5 Multiple myeloma; TGCT cis rs7584330 0.737 rs1497129 chr2:238369184 C/T cg14458575 chr2:238380390 NA 0.49 7.88 0.58 1.41e-12 Prostate cancer; TGCT cis rs9926296 0.562 rs4785725 chr16:89893243 A/G cg04287289 chr16:89883240 FANCA 0.67 6.82 0.52 3.63e-10 Vitiligo; TGCT cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg21433313 chr16:3507492 NAT15 -0.4 -5.32 -0.43 4.71e-7 Tuberculosis; TGCT cis rs208515 0.556 rs12214562 chr6:66681011 T/A cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs17039065 0.920 rs1017431 chr4:109474091 A/C cg16022748 chr4:109541635 LOC285456;RPL34 0.82 4.93 0.4 2.63e-6 Gut microbiome composition (summer); TGCT cis rs6912958 1.000 rs13214153 chr6:88153983 G/C cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.69 -0.39 7.08e-6 Monocyte percentage of white cells; TGCT cis rs17221829 0.733 rs10765222 chr11:89372109 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs6598955 0.671 rs11247880 chr1:26568926 G/A cg04990556 chr1:26633338 UBXN11 0.64 5.11 0.42 1.19e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs957742 chr4:99029409 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7100689 0.646 rs10736348 chr10:82139244 C/A cg01528321 chr10:82214614 TSPAN14 0.81 8.27 0.6 1.71e-13 Post bronchodilator FEV1; TGCT cis rs1008375 0.932 rs9283698 chr4:17662471 T/C cg10189774 chr4:17578691 LAP3 0.52 4.55 0.38 1.29e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg14893161 chr1:205819251 PM20D1 0.66 10.45 0.68 1.04e-18 Menarche (age at onset); TGCT cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg18252515 chr7:66147081 NA -1.1 -7.18 -0.54 5.77e-11 Diabetic kidney disease; TGCT cis rs6921919 0.583 rs7759191 chr6:28353434 A/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.32 -0.43 4.76e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1372520 0.684 rs2197120 chr4:90729602 A/G cg15133208 chr4:90757351 SNCA -0.52 -6.07 -0.48 1.44e-8 Neuroticism; TGCT cis rs3096299 0.606 rs2965960 chr16:89541795 G/A cg02187348 chr16:89574699 SPG7 0.47 4.51 0.38 1.47e-5 Multiple myeloma (IgH translocation); TGCT cis rs75059851 0.756 rs11223646 chr11:133839560 C/T cg14047540 chr11:133829660 NA -0.53 -5.37 -0.43 3.7e-7 Schizophrenia; TGCT cis rs7917772 0.503 rs7899576 chr10:104307504 G/A cg05855489 chr10:104503620 C10orf26 -0.61 -5.41 -0.44 3.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28595532 0.841 rs114735834 chr4:119772722 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs7772486 0.754 rs4896841 chr6:146041522 T/C cg05347473 chr6:146136440 FBXO30 -0.52 -4.85 -0.4 3.61e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs875971 0.929 rs4122249 chr7:65920936 T/C cg11764359 chr7:65958608 NA 0.6 5.43 0.44 2.85e-7 Aortic root size; TGCT cis rs3780378 1.000 rs3780378 chr9:5112288 C/T cg02405213 chr9:5042618 JAK2 -0.61 -7.89 -0.58 1.36e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7043114 0.507 rs10992340 chr9:95209693 T/C cg14631576 chr9:95140430 CENPP -0.28 -4.58 -0.38 1.11e-5 Height; TGCT cis rs7829975 0.806 rs2428 chr8:8641145 C/T cg15556689 chr8:8085844 FLJ10661 0.73 6.5 0.5 1.75e-9 Mood instability; TGCT cis rs1062177 1.000 rs17741826 chr5:151149262 C/T cg00977110 chr5:151150581 G3BP1 -0.41 -4.62 -0.38 9.52e-6 Preschool internalizing problems; TGCT cis rs651907 0.513 rs34963630 chr3:101504817 C/T cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg03806693 chr22:41940476 POLR3H -1.14 -13.38 -0.77 8.05e-26 Vitiligo; TGCT cis rs6964587 0.869 rs10250641 chr7:91490746 C/T cg17063962 chr7:91808500 NA 0.82 8.89 0.62 5.87e-15 Breast cancer; TGCT cis rs494003 1.000 rs11227284 chr11:65503224 C/T cg04293602 chr11:65553660 OVOL1 0.37 4.65 0.39 8.5e-6 Systemic lupus erythematosus; TGCT cis rs7523050 0.730 rs72984614 chr1:109435848 T/C cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs8100891 0.665 rs7259259 chr19:32819841 G/C cg16662424 chr19:32837316 ZNF507 -0.43 -5.24 -0.43 6.57e-7 Neuroticism; TGCT cis rs801193 0.569 rs13226966 chr7:66233623 A/G cg11764359 chr7:65958608 NA 0.51 4.48 0.37 1.7e-5 Aortic root size; TGCT cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.69e-9 Blood metabolite levels; TGCT cis rs28595532 0.920 rs114390336 chr4:119771452 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg11890956 chr21:40555474 PSMG1 1.06 10.7 0.69 2.44e-19 Cognitive function; TGCT cis rs782590 0.729 rs706548 chr2:55850106 C/G cg18811423 chr2:55921094 PNPT1 0.55 5.82 0.46 4.7e-8 Metabolic syndrome; TGCT cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg14983838 chr19:29218262 NA 0.86 7.0 0.53 1.42e-10 Methadone dose in opioid dependence; TGCT cis rs769267 0.895 rs2905435 chr19:19495954 G/A cg03709012 chr19:19516395 GATAD2A -0.75 -6.51 -0.5 1.71e-9 Tonsillectomy; TGCT cis rs11792861 0.926 rs72607173 chr9:111879398 T/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 5.01 0.41 1.8e-6 Menarche (age at onset); TGCT cis rs10484885 0.571 rs56019056 chr6:90630623 G/C cg10278699 chr6:90661155 BACH2 0.32 4.76 0.39 5.2e-6 QRS interval (sulfonylurea treatment interaction); TGCT cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg00786635 chr1:25594202 NA 0.61 6.37 0.5 3.32e-9 Erythrocyte sedimentation rate; TGCT cis rs737008 0.922 rs2550475 chr16:11371986 C/T cg00044050 chr16:11439710 C16orf75 0.73 7.56 0.56 7.92e-12 Obesity-related traits; TGCT cis rs8014252 0.803 rs12586299 chr14:71085215 C/T cg11204974 chr14:71022665 NA -0.56 -4.7 -0.39 6.89e-6 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs7100689 0.555 rs1934146 chr10:82062121 C/A cg01528321 chr10:82214614 TSPAN14 0.75 7.46 0.56 1.32e-11 Post bronchodilator FEV1; TGCT cis rs2235642 0.821 rs2281234 chr16:1602938 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.85 -0.46 4.15e-8 Coronary artery disease; TGCT cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg03806693 chr22:41940476 POLR3H 0.99 11.15 0.71 2.05e-20 Vitiligo; TGCT cis rs9486715 0.867 rs3860243 chr6:96905303 T/G cg18709589 chr6:96969512 KIAA0776 0.77 7.64 0.57 4.99e-12 Headache; TGCT cis rs7829975 0.742 rs882462 chr8:8678530 G/A cg15556689 chr8:8085844 FLJ10661 0.69 6.43 0.5 2.56e-9 Mood instability; TGCT cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg07092213 chr7:1199455 ZFAND2A -0.43 -4.62 -0.38 9.36e-6 Longevity;Endometriosis; TGCT cis rs2688608 0.592 rs7080579 chr10:75504029 T/A cg15838173 chr10:75533400 FUT11 -0.31 -4.89 -0.4 3.12e-6 Inflammatory bowel disease; TGCT cis rs2836974 0.931 rs12151994 chr21:40690397 A/C cg06238570 chr21:40685208 BRWD1 0.7 6.11 0.48 1.2e-8 Cognitive function; TGCT cis rs1670533 1.000 rs10084849 chr4:1053586 T/C cg27284194 chr4:1044797 NA 0.66 5.69 0.45 8.85e-8 Recombination rate (females); TGCT cis rs17270561 0.578 rs76182885 chr6:25904085 G/C cg17691542 chr6:26056736 HIST1H1C 0.89 6.28 0.49 5.19e-9 Iron status biomarkers; TGCT cis rs7216064 1.000 rs62084214 chr17:65843325 C/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7208859 0.673 rs216410 chr17:28903831 C/G cg04154034 chr17:28927549 LRRC37B2 -0.76 -4.46 -0.37 1.82e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9549367 0.789 rs12584813 chr13:113895443 C/G cg00898013 chr13:113819073 PROZ -0.46 -4.78 -0.39 4.86e-6 Platelet distribution width; TGCT cis rs2832077 0.527 rs2250141 chr21:30241984 A/T cg24692254 chr21:30365293 RNF160 0.57 4.78 0.39 4.87e-6 Cognitive test performance; TGCT cis rs9372498 0.536 rs72952793 chr6:118892979 T/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.06 -0.41 1.5e-6 Diastolic blood pressure; TGCT cis rs6121246 0.559 rs10439607 chr20:30258541 G/A cg13852791 chr20:30311386 BCL2L1 0.84 8.15 0.59 3.38e-13 Mean corpuscular hemoglobin; TGCT cis rs1949733 1.000 rs6837429 chr4:8502374 A/G cg11789530 chr4:8429930 ACOX3 0.64 5.95 0.47 2.52e-8 Response to antineoplastic agents; TGCT cis rs4654899 0.785 rs9426736 chr1:21505931 T/G cg01072550 chr1:21505969 NA -0.57 -9.4 -0.64 3.62e-16 Superior frontal gyrus grey matter volume; TGCT cis rs9611565 0.879 rs4820437 chr22:41761290 T/C cg06481639 chr22:41940642 POLR3H -0.58 -5.01 -0.41 1.81e-6 Vitiligo; TGCT cis rs7659604 0.539 rs2221628 chr4:122795361 G/A cg20573242 chr4:122745356 CCNA2 0.64 5.58 0.45 1.43e-7 Type 2 diabetes; TGCT cis rs10992471 0.580 rs724102 chr9:95383290 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -4.59 -0.38 1.07e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7208859 0.673 rs73271887 chr17:29154935 T/C cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11711311 1.000 rs9828449 chr3:113518602 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs2836974 0.555 rs35909862 chr21:40621158 G/A cg11890956 chr21:40555474 PSMG1 -0.76 -7.43 -0.56 1.54e-11 Cognitive function; TGCT cis rs7223966 0.729 rs7921 chr17:62006259 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.57 0.38 1.15e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3091242 1.000 rs3091242 chr1:25674785 C/T cg09222892 chr1:25734099 RHCE -0.42 -6.69 -0.52 6.75e-10 Erythrocyte sedimentation rate; TGCT cis rs9807989 0.801 rs6752482 chr2:102967858 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs4654899 0.802 rs935918 chr1:21145660 C/T cg01072550 chr1:21505969 NA -0.45 -6.65 -0.51 8.51e-10 Superior frontal gyrus grey matter volume; TGCT cis rs1801251 1.000 rs283477 chr2:233649427 A/G cg25237894 chr2:233734115 C2orf82 0.27 4.66 0.39 8.04e-6 Coronary artery disease; TGCT cis rs1355223 0.583 rs2915238 chr11:34884405 C/A cg11058730 chr11:34937778 PDHX;APIP 0.8 8.94 0.63 4.53e-15 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs4478858 0.735 rs4494186 chr1:31857847 G/A cg07478791 chr1:31886160 SERINC2 0.47 4.7 0.39 6.79e-6 Alcohol dependence; TGCT cis rs2013441 1.000 rs2703789 chr17:20162923 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs231513 0.954 rs231504 chr17:41970906 C/G cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs116095464 0.867 rs10074958 chr5:230828 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs4911259 0.552 rs13041458 chr20:31467376 G/T cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT trans rs1005277 0.579 rs2474580 chr10:38398713 G/A cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs3806843 0.576 rs246008 chr5:140338485 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs6671200 0.607 rs3753872 chr1:95699184 T/G cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs2637266 0.765 rs2395391 chr10:78359932 G/A cg18941641 chr10:78392320 NA 0.42 5.39 0.44 3.36e-7 Pulmonary function; TGCT cis rs796364 0.616 rs769955 chr2:200692595 C/T cg17644776 chr2:200775616 C2orf69 0.34 4.84 0.4 3.76e-6 Schizophrenia; TGCT cis rs12220238 0.722 rs4745749 chr10:76393742 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.64 5.19 0.42 8.46e-7 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs854765 0.547 rs2955353 chr17:17948979 T/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs6770219 0.516 rs59725628 chr3:186136635 G/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs453301 0.653 rs7853 chr8:8890814 A/G cg06636001 chr8:8085503 FLJ10661 0.78 7.14 0.54 6.86e-11 Joint mobility (Beighton score); TGCT cis rs9942416 0.660 rs111937612 chr5:74979631 C/T cg19683494 chr5:74908142 NA 0.59 6.29 0.49 4.99e-9 Age-related disease endophenotypes; TGCT cis rs4851254 0.660 rs59447631 chr2:100691493 T/C cg22139774 chr2:100720529 AFF3 -0.45 -4.88 -0.4 3.13e-6 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.559 rs17428071 chr7:106878200 C/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs7682991 chr4:98982595 C/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs941873 0.868 rs10740497 chr10:81126380 T/C cg09469691 chr10:81107165 PPIF 0.64 6.53 0.51 1.49e-9 Height; TGCT cis rs2932538 0.961 rs2932529 chr1:113193364 G/A cg22162597 chr1:113214053 CAPZA1 -0.28 -5.83 -0.46 4.4e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs67073037 0.955 rs3924272 chr2:29167678 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs9311474 0.713 rs352171 chr3:52234203 A/G cg07507251 chr3:52567010 NT5DC2 0.39 5.12 0.42 1.16e-6 Electroencephalogram traits; TGCT cis rs10811516 0.520 rs4568676 chr9:21184475 C/G cg23029519 chr9:21187344 IFNA4 0.29 4.59 0.38 1.09e-5 Response to mepolizumab in severe asthma; TGCT cis rs907683 0.584 rs12920 chr2:220285666 C/G cg15015639 chr2:220282977 DES 0.39 4.83 0.4 3.88e-6 Resting heart rate; TGCT cis rs826838 1.000 rs7975243 chr12:38849220 C/T cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs11122272 0.668 rs1538664 chr1:231555295 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.6 -5.71 -0.46 7.8e-8 Hemoglobin concentration; TGCT cis rs4786125 0.581 rs7194903 chr16:6918194 A/G cg03623568 chr16:6915990 A2BP1 -0.44 -6.57 -0.51 1.27e-9 Heart rate variability traits (SDNN); TGCT cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg09222892 chr1:25734099 RHCE -0.41 -6.8 -0.52 3.99e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs2361718 1.000 rs2361718 chr17:78103466 C/T cg09238746 chr17:78121135 EIF4A3 -0.51 -4.57 -0.38 1.16e-5 Yeast infection; TGCT cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs453301 0.686 rs28482034 chr8:8869664 G/A cg15556689 chr8:8085844 FLJ10661 -0.64 -5.29 -0.43 5.37e-7 Joint mobility (Beighton score); TGCT cis rs11578119 0.902 rs2421326 chr1:170512369 T/A cg09767346 chr1:170501363 GORAB -0.62 -5.11 -0.42 1.18e-6 Male-pattern baldness; TGCT cis rs7804356 1.000 rs10276471 chr7:26837940 C/G cg03456212 chr7:26904342 SKAP2 -0.61 -4.7 -0.39 6.82e-6 Type 1 diabetes; TGCT cis rs854765 0.547 rs2955372 chr17:17970229 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.28 -0.6 1.68e-13 Total body bone mineral density; TGCT cis rs10465746 0.780 rs2389648 chr1:84403031 C/T cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT trans rs1814175 0.817 rs7483795 chr11:49704930 G/A cg15704280 chr7:45808275 SEPT13 -0.71 -8.23 -0.59 2.14e-13 Height; TGCT cis rs9814567 0.964 rs9833753 chr3:134213665 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs789852 1.000 rs789850 chr3:194325496 T/C cg18000598 chr3:194342907 TMEM44 -0.81 -5.27 -0.43 5.93e-7 QT interval; TGCT cis rs10114408 0.918 rs4523325 chr9:96661833 G/A cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs11997175 0.784 rs36083407 chr8:33812930 G/T ch.8.33884649F chr8:33765107 NA 0.34 5.28 0.43 5.56e-7 Body mass index; TGCT cis rs651907 0.588 rs1378838 chr3:101634543 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.5 4.79 0.4 4.65e-6 Colorectal cancer; TGCT cis rs72781680 0.898 rs55657921 chr2:24008091 C/G cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs1775715 0.737 rs2799017 chr10:32203460 A/G cg14930904 chr10:32216787 ARHGAP12 0.53 5.12 0.42 1.15e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2115630 1.000 rs1030863 chr15:85282635 C/T cg12501888 chr15:85177176 SCAND2 -0.48 -4.49 -0.37 1.6e-5 P wave terminal force; TGCT cis rs709400 0.628 rs10141120 chr14:103923008 T/C cg12935359 chr14:103987150 CKB -0.35 -5.33 -0.43 4.54e-7 Body mass index; TGCT cis rs9952991 0.941 rs7237497 chr18:12777325 T/C cg09945482 chr18:12777974 NA 0.51 4.86 0.4 3.47e-6 Inflammatory skin disease; TGCT cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs7681440 0.835 rs7668531 chr4:90791819 G/T cg20003494 chr4:90757398 SNCA -0.62 -5.94 -0.47 2.67e-8 Dementia with Lewy bodies; TGCT cis rs9534288 0.797 rs2104515 chr13:46569846 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs1577917 1.000 rs12203924 chr6:86776412 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.09 -0.42 1.27e-6 Response to antipsychotic treatment; TGCT cis rs6121246 0.909 rs57726761 chr20:30314046 A/G cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs13108904 0.539 rs13135102 chr4:1330983 A/C cg13395646 chr4:1353034 KIAA1530 -0.55 -7.57 -0.56 7.56e-12 Obesity-related traits; TGCT cis rs10744422 1.000 rs10744434 chr12:123368419 T/A cg25930673 chr12:123319894 HIP1R -0.85 -5.03 -0.41 1.69e-6 Schizophrenia; TGCT cis rs1334894 1.000 rs10498734 chr6:35559773 A/C cg24281267 chr6:35479648 TULP1 -0.44 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT trans rs7618501 0.966 rs2352974 chr3:49890613 C/T cg21659725 chr3:3221576 CRBN 0.88 12.71 0.75 3.19e-24 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg02458000 chr6:26745757 NA 0.71 7.0 0.53 1.43e-10 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs10189235 chr2:43745520 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.77 4.68 0.39 7.28e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6138458 1.000 rs6106984 chr20:24977006 T/C cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs11122272 0.735 rs2808580 chr1:231509259 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs6733011 0.628 rs4851163 chr2:99466664 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.46 -4.51 -0.38 1.46e-5 Bipolar disorder; TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs7657490 chr4:99043973 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs66573146 1.000 rs28384174 chr4:6961107 G/T cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2304725 0.526 rs1601364 chr3:10830250 C/T cg15914589 chr3:10206523 IRAK2 -0.47 -4.49 -0.37 1.61e-5 Pulmonary function in asthmatics; TGCT cis rs2013441 0.669 rs62066947 chr17:20351458 G/A cg23224458 chr17:20280056 CCDC144C 0.39 4.55 0.38 1.25e-5 Obesity-related traits; TGCT cis rs9291683 0.530 rs4697698 chr4:9942577 C/T cg11266682 chr4:10021025 SLC2A9 0.63 8.46 0.6 6.42e-14 Bone mineral density; TGCT cis rs6089829 0.962 rs2277769 chr20:61666805 C/T cg18188782 chr20:61659543 NA 0.45 5.51 0.44 1.95e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs13064411 0.735 rs9875025 chr3:113147552 T/C cg10517650 chr3:113235015 CCDC52 -0.35 -4.63 -0.38 9.06e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9611565 0.605 rs202638 chr22:41855458 A/G cg06634786 chr22:41940651 POLR3H 0.86 8.15 0.59 3.45e-13 Vitiligo; TGCT cis rs8111998 0.826 rs6511364 chr19:22765808 C/T cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg13012494 chr21:47604986 C21orf56 -0.37 -4.78 -0.39 4.81e-6 Testicular germ cell tumor; TGCT cis rs7172809 0.643 rs907370 chr15:77844272 G/C cg22256960 chr15:77711686 NA -0.48 -4.77 -0.39 5.1e-6 Glucose homeostasis traits; TGCT cis rs11190604 1.000 rs2495747 chr10:102328247 C/T cg23241863 chr10:102295624 HIF1AN 0.67 5.1 0.42 1.23e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12210905 0.688 rs72845011 chr6:27500822 T/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs6893807 1.000 rs13163173 chr5:87943620 C/A cg24804195 chr5:87968844 LOC645323 0.74 5.2 0.42 8.09e-7 Body mass index; TGCT cis rs4853012 0.838 rs6707729 chr2:74344685 G/A cg01017244 chr2:74357527 NA 0.5 8.39 0.6 9.34e-14 Gestational age at birth (maternal effect); TGCT cis rs4663866 1.000 rs71426509 chr2:239175334 A/C cg17283117 chr2:239148619 HES6 0.98 4.52 0.38 1.42e-5 Irritable bowel syndrome; TGCT cis rs2013441 1.000 rs2243732 chr17:20088589 C/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs4494114 0.967 rs1886748 chr1:39333775 C/A cg25970120 chr1:39325951 RRAGC -0.6 -6.25 -0.49 5.96e-9 Blood protein levels; TGCT cis rs16957091 0.606 rs2412748 chr15:43227515 G/A cg17935677 chr15:44119062 WDR76 0.52 4.67 0.39 7.6e-6 MGMT methylation in smokers; TGCT cis rs4819052 0.851 rs914214 chr21:46697820 G/T cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9952991 0.883 rs2542148 chr18:12777573 C/G cg23544223 chr18:12777786 NA 0.63 6.02 0.48 1.85e-8 Inflammatory skin disease; TGCT cis rs877282 0.898 rs34490091 chr10:765800 A/C cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs9818758 0.607 rs73084135 chr3:49272218 A/G cg07636037 chr3:49044803 WDR6 -1.01 -4.93 -0.4 2.63e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6540559 0.673 rs6694552 chr1:209976459 A/C cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs6671200 0.790 rs259357 chr1:95711478 G/T cg03123541 chr1:95699097 RWDD3 -0.91 -6.4 -0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs9638182 0.945 rs35368205 chr7:73017657 C/T cg14087351 chr7:73037990 MLXIPL -0.57 -4.77 -0.39 5.02e-6 Triglycerides; TGCT trans rs986417 0.818 rs761557 chr14:61077484 C/T cg12876356 chr1:92946825 GFI1 0.71 6.93 0.53 1.98e-10 Gut microbiota (bacterial taxa); TGCT cis rs12477438 0.501 rs11685756 chr2:99766215 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs2010099 0.583 rs112519474 chr3:124315623 G/A cg17170942 chr3:124452405 UMPS -0.4 -4.64 -0.38 8.55e-6 Thyroid peroxidase antibody levels; TGCT cis rs763014 0.932 rs2384975 chr16:651115 G/T cg09263875 chr16:632152 PIGQ 0.31 6.93 0.53 2.06e-10 Height; TGCT cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg18765753 chr7:1198926 ZFAND2A -0.4 -4.52 -0.38 1.4e-5 Longevity;Endometriosis; TGCT cis rs7552404 0.924 rs2275378 chr1:76198436 T/C cg03433033 chr1:76189801 ACADM 0.81 9.7 0.66 6.89e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs2836950 0.545 rs2297256 chr21:40558421 C/T cg06238570 chr21:40685208 BRWD1 -0.62 -6.51 -0.5 1.68e-9 Menarche (age at onset); TGCT cis rs13177918 0.626 rs3819332 chr5:149828750 G/C cg14059543 chr5:149831962 NA -0.69 -9.27 -0.64 7.32e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg18867708 chr6:26865862 GUSBL1 0.41 5.48 0.44 2.3e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs8180040 0.764 rs11708451 chr3:47198826 G/A cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT trans rs4948418 0.579 rs10821745 chr10:62136206 T/G cg03916014 chr16:1722352 CRAMP1L 0.45 6.84 0.52 3.16e-10 Bipolar disorder; TGCT cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg03264133 chr6:25882463 NA -0.72 -6.85 -0.52 3.11e-10 Intelligence (multi-trait analysis); TGCT cis rs9372498 0.536 rs9489477 chr6:118946192 T/G cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs7937682 0.663 rs35581942 chr11:111756286 C/T cg09085632 chr11:111637200 PPP2R1B 0.84 7.27 0.55 3.45e-11 Primary sclerosing cholangitis; TGCT cis rs8141529 0.748 rs5762874 chr22:29269658 C/G cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs7255045 0.789 rs1078264 chr19:12963143 T/C cg23899408 chr19:12877188 HOOK2 -0.61 -4.99 -0.41 1.97e-6 Mean corpuscular volume; TGCT cis rs7666738 0.791 rs1426674 chr4:98924247 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2702888 0.503 rs2738143 chr8:6758816 G/A cg26795848 chr8:6756730 NA -0.31 -6.46 -0.5 2.11e-9 Blood pressure; TGCT cis rs3784262 0.669 rs4646594 chr15:58302386 C/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.85e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6831352 0.918 rs13133647 chr4:100058727 C/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs10779751 0.734 rs2748878 chr1:11129434 T/C cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs7833790 0.963 rs2400473 chr8:82703403 C/T cg27398817 chr8:82754497 SNX16 -0.93 -6.44 -0.5 2.37e-9 Diastolic blood pressure; TGCT trans rs4820792 0.945 rs2017309 chr22:29131426 A/T cg00373991 chr10:102763563 LZTS2 0.32 6.77 0.52 4.68e-10 Breast size; TGCT cis rs1568889 1.000 rs61236373 chr11:28212720 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 8.17 0.59 3.04e-13 Bipolar disorder; TGCT cis rs13256369 1.000 rs12550762 chr8:8576535 T/A cg17143192 chr8:8559678 CLDN23 0.62 5.87 0.47 3.67e-8 Obesity-related traits; TGCT cis rs7666738 0.830 rs6854994 chr4:98977624 C/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg10802521 chr3:52805072 NEK4 -0.78 -10.09 -0.67 7.59e-18 Bipolar disorder; TGCT cis rs9467773 1.000 rs9467787 chr6:26556769 G/T cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.699 rs6449158 chr4:9960459 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.54 -0.56 8.83e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1801251 0.711 rs778368 chr2:233745333 G/C cg25237894 chr2:233734115 C2orf82 -0.31 -5.84 -0.46 4.3e-8 Coronary artery disease; TGCT cis rs7647973 0.710 rs1491983 chr3:49639803 G/T cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs6598955 0.671 rs11247905 chr1:26627907 G/C cg04990556 chr1:26633338 UBXN11 0.67 5.44 0.44 2.77e-7 Obesity-related traits; TGCT cis rs11673344 0.504 rs6510588 chr19:37597395 G/T cg08039142 chr19:36980659 ZNF566 -0.51 -4.78 -0.39 4.81e-6 Obesity-related traits; TGCT cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs7119 0.717 rs12917175 chr15:77818193 A/G cg27398640 chr15:77910606 LINGO1 -0.26 -4.67 -0.39 7.6e-6 Type 2 diabetes; TGCT cis rs9914988 0.943 rs66588554 chr17:27141110 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs801193 1.000 rs10252765 chr7:66228732 C/G cg00343986 chr7:65444356 GUSB 0.22 4.8 0.4 4.51e-6 Aortic root size; TGCT cis rs2153535 0.580 rs7742794 chr6:8459723 C/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs589249 0.926 rs4652927 chr1:37188699 G/T cg04012535 chr1:37176647 NA 0.35 5.57 0.45 1.52e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs514406 0.825 rs6693210 chr1:53223398 A/G cg16325326 chr1:53192061 ZYG11B -0.71 -8.61 -0.61 2.81e-14 Monocyte count; TGCT cis rs9788682 0.747 rs2938671 chr15:78732754 A/G cg24631222 chr15:78858424 CHRNA5 -0.61 -4.55 -0.38 1.25e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs829661 0.947 rs829665 chr2:30724701 T/A cg12454169 chr2:30669597 LCLAT1 0.73 6.92 0.53 2.1e-10 Midgestational circulating levels of PBDEs (fetal genetic effect); TGCT cis rs1843834 0.505 rs2140508 chr2:225355839 G/T cg22455342 chr2:225449267 CUL3 1.04 10.81 0.7 1.35e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs9457247 1.000 rs376574 chr6:167389956 A/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs4478858 0.684 rs1532861 chr1:31766491 T/C cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs2191566 0.664 rs4803669 chr19:44539962 C/A cg03039196 chr19:44506973 ZNF230 0.53 4.47 0.37 1.78e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs1697139 0.583 rs1428474 chr5:66544015 C/A cg11553311 chr5:66541588 NA 0.29 6.27 0.49 5.38e-9 Breast cancer; TGCT cis rs9486719 1.000 rs2472895 chr6:96870387 A/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7119 0.717 rs12902925 chr15:77819141 T/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.61 -0.38 9.81e-6 Type 2 diabetes; TGCT cis rs801193 1.000 rs2707854 chr7:66212597 G/A cg00343986 chr7:65444356 GUSB 0.24 5.25 0.43 6.3e-7 Aortic root size; TGCT cis rs11785400 0.793 rs1056012 chr8:143740167 A/G cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs7552404 0.961 rs17587071 chr1:76225083 A/C cg22875332 chr1:76189707 ACADM 0.78 8.96 0.63 4.17e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg05552183 chr6:42928497 GNMT 0.52 4.57 0.38 1.16e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg14004847 chr7:1930337 MAD1L1 0.31 5.46 0.44 2.47e-7 Bipolar disorder and schizophrenia; TGCT cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT trans rs1005277 0.579 rs1740737 chr10:38499365 G/T cg17830980 chr10:43048298 ZNF37B -0.84 -10.45 -0.68 1.02e-18 Extrinsic epigenetic age acceleration; TGCT cis rs7940866 0.834 rs10791105 chr11:130839161 A/G cg12179176 chr11:130786555 SNX19 0.62 5.93 0.47 2.75e-8 Schizophrenia; TGCT cis rs7044106 0.791 rs2416798 chr9:123480603 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.98 0.41 2.12e-6 Hip circumference adjusted for BMI; TGCT cis rs11696501 0.739 rs6073821 chr20:44251791 A/G cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs7772486 0.754 rs9373476 chr6:146139741 C/G cg13319975 chr6:146136371 FBXO30 -0.52 -4.65 -0.39 8.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769707 0.846 rs5770610 chr22:50036897 A/C cg20744362 chr22:50050164 C22orf34 0.27 4.57 0.38 1.18e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4925386 0.681 rs2427296 chr20:60927475 G/A cg06026331 chr20:60912101 LAMA5 0.34 5.46 0.44 2.48e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs9357506 1.000 rs9381444 chr6:46316690 C/A cg21115430 chr6:46460003 NA -0.25 -4.8 -0.4 4.49e-6 Body mass index; TGCT cis rs769267 0.895 rs2965182 chr19:19548246 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.51 0.5 1.71e-9 Tonsillectomy; TGCT cis rs71636778 0.509 rs12741472 chr1:27221609 A/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs539096 0.624 rs11210892 chr1:44100084 A/G cg12908607 chr1:44402522 ARTN 0.43 4.87 0.4 3.37e-6 Intelligence (multi-trait analysis); TGCT cis rs2070433 0.500 rs9306156 chr21:47960493 T/C cg12379764 chr21:47803548 PCNT 0.44 4.58 0.38 1.11e-5 Lymphocyte counts; TGCT cis rs2282802 0.685 rs2053055 chr5:139646776 C/T cg01081189 chr5:139537190 NA 0.28 5.15 0.42 9.75e-7 Intelligence (multi-trait analysis); TGCT trans rs4332037 0.539 rs56180486 chr7:2050747 C/T cg25206134 chr2:45395956 NA 0.99 7.46 0.56 1.34e-11 Bipolar disorder; TGCT trans rs4824093 0.541 rs8142132 chr22:50211294 C/T cg09872104 chr7:134855509 C7orf49 -1.12 -8.69 -0.62 1.84e-14 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs778371 0.649 rs13021823 chr2:233686862 A/G cg08000102 chr2:233561755 GIGYF2 -0.67 -7.47 -0.56 1.25e-11 Schizophrenia; TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg26354017 chr1:205819088 PM20D1 0.57 7.09 0.54 8.8e-11 Menarche (age at onset); TGCT cis rs651907 0.557 rs34181125 chr3:101490278 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.53 5.02 0.41 1.77e-6 Colorectal cancer; TGCT cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg03188948 chr7:1209495 NA 0.65 5.39 0.44 3.36e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2562456 0.720 rs6511250 chr19:21656046 C/T cg01304269 chr19:21688519 ZNF429 -0.55 -4.53 -0.38 1.34e-5 Pain; TGCT cis rs240764 0.658 rs7746947 chr6:101188708 G/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs9926296 0.744 rs164746 chr16:89709019 C/T cg04287289 chr16:89883240 FANCA -0.49 -4.7 -0.39 6.94e-6 Vitiligo; TGCT cis rs1670533 1.000 rs11731320 chr4:1057916 T/A cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs4975616 0.836 rs460073 chr5:1336459 T/C cg07493874 chr5:1342172 CLPTM1L -0.28 -6.88 -0.53 2.69e-10 Lung cancer; TGCT cis rs1552244 0.882 rs13099507 chr3:10031603 G/A cg00149659 chr3:10157352 C3orf10 0.79 4.96 0.41 2.27e-6 Alzheimer's disease; TGCT cis rs9814567 0.752 rs9846111 chr3:134335034 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.73 -6.66 -0.51 7.8e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1008375 1.000 rs10939748 chr4:17691230 T/C cg18681998 chr4:17616180 MED28 0.79 7.53 0.56 9.23e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs826838 0.754 rs2387920 chr12:38626351 A/G cg26384229 chr12:38710491 ALG10B 0.9 8.1 0.59 4.36e-13 Heart rate; TGCT cis rs2456568 0.803 rs10765642 chr11:93640355 C/T cg16099599 chr11:93583650 C11orf90 0.39 4.88 0.4 3.17e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7091068 0.616 rs4322326 chr10:95483382 A/T cg20715218 chr10:95462985 C10orf4 0.56 5.19 0.42 8.51e-7 Urinary tract infection frequency; TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg17775962 chr7:1200435 ZFAND2A 0.28 4.8 0.4 4.57e-6 Longevity;Endometriosis; TGCT cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg20203395 chr5:56204925 C5orf35 -0.56 -4.8 -0.4 4.39e-6 Initial pursuit acceleration; TGCT cis rs2663905 0.611 rs1509559 chr15:81391411 G/A cg18028999 chr15:81426610 C15orf26 -0.54 -5.23 -0.42 7.14e-7 QT interval (drug interaction); TGCT cis rs10501293 1.000 rs10501293 chr11:43086094 G/T cg03447554 chr11:43094025 NA 0.47 6.64 0.51 8.97e-10 Cognitive performance; TGCT cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg24531977 chr5:56204891 C5orf35 -0.74 -7.1 -0.54 8.53e-11 Initial pursuit acceleration; TGCT cis rs2842992 0.662 rs2273825 chr6:160211424 A/C cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Vitiligo; TGCT cis rs12360000 0.740 rs55679834 chr10:1910856 T/A cg26364871 chr10:1889757 NA 0.4 4.58 0.38 1.12e-5 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs1008375 0.932 rs10009933 chr4:17670107 A/C cg16339924 chr4:17578868 LAP3 0.54 4.48 0.37 1.67e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.862 rs778684 chr7:65836403 A/T cg11764359 chr7:65958608 NA 0.58 5.31 0.43 4.91e-7 Aortic root size; TGCT cis rs9611565 0.592 rs5751129 chr22:42015765 C/T cg06481639 chr22:41940642 POLR3H 0.61 5.32 0.43 4.75e-7 Vitiligo; TGCT cis rs10744422 1.000 rs12255 chr12:123350204 C/T cg25930673 chr12:123319894 HIP1R -0.9 -5.06 -0.41 1.49e-6 Schizophrenia; TGCT cis rs904251 0.523 rs2776874 chr6:37483197 C/T cg08126542 chr6:37504118 NA -0.38 -5.81 -0.46 4.9e-8 Cognitive performance; TGCT cis rs9911578 1.000 rs12602346 chr17:56901713 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs7209700 0.614 rs7225927 chr17:45323934 A/G cg21624342 chr17:45890973 OSBPL7 0.16 4.46 0.37 1.8e-5 IgG glycosylation; TGCT cis rs7208859 0.673 rs11655623 chr17:29162173 T/C cg18442181 chr17:29233375 C17orf42 -0.76 -4.5 -0.38 1.52e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6912958 0.781 rs9450732 chr6:88249826 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.626 rs11130217 chr3:49737323 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs2243480 1.000 rs778729 chr7:65824419 T/C cg18252515 chr7:66147081 NA -1.22 -7.33 -0.55 2.53e-11 Diabetic kidney disease; TGCT trans rs7618501 1.000 rs3749241 chr3:49744392 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs7302981 0.967 rs35998534 chr12:50556782 A/G cg23855989 chr12:50355821 AQP5 0.3 4.46 0.37 1.84e-5 Systolic blood pressure; TGCT cis rs11031096 0.655 rs11031252 chr11:4211165 A/G cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7267979 1.000 rs6050562 chr20:25336186 C/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7618501 1.000 rs3749240 chr3:49750188 T/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs589249 0.926 rs6677366 chr1:37187504 A/G cg04012535 chr1:37176647 NA 0.35 5.57 0.45 1.52e-7 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs11098499 0.863 rs3775841 chr4:120425777 A/C cg09307838 chr4:120376055 NA 0.68 6.29 0.49 4.97e-9 Corneal astigmatism; TGCT cis rs933688 0.877 rs1477349 chr5:90707773 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 8.03 0.58 6.35e-13 Smoking behavior; TGCT cis rs28374715 0.681 rs59000092 chr15:41626148 A/G cg18705301 chr15:41695430 NDUFAF1 -0.87 -13.45 -0.77 5.4e-26 Ulcerative colitis; TGCT trans rs2469997 0.925 rs2470001 chr8:120356402 C/T cg01792902 chr3:178864926 PIK3CA 0.84 6.9 0.53 2.41e-10 Hypertension (SNP x SNP interaction); TGCT cis rs7017914 0.905 rs4738105 chr8:71958918 A/C cg23757474 chr8:71581111 LACTB2;XKR9 0.55 5.07 0.41 1.39e-6 Bone mineral density; TGCT cis rs11264213 0.901 rs614235 chr1:36450565 G/A cg07093915 chr1:36184400 C1orf216 0.65 4.51 0.38 1.46e-5 Schizophrenia; TGCT cis rs910187 0.596 rs6066222 chr20:45801917 G/A cg27589058 chr20:45804311 EYA2 -0.37 -7.95 -0.58 9.93e-13 Migraine; TGCT cis rs1865760 0.663 rs9467656 chr6:25993559 G/A cg17042849 chr6:26104293 HIST1H4C -0.59 -5.43 -0.44 2.91e-7 Height; TGCT cis rs2842992 0.789 rs2475566 chr6:160148741 C/T cg11366901 chr6:160182831 ACAT2 1.04 6.93 0.53 2.05e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs981844 0.712 rs1012029 chr4:154749233 C/T cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs350251 0.865 rs350271 chr16:12235372 A/G cg01574788 chr16:12184133 SNX29 0.36 4.71 0.39 6.63e-6 Intelligence (multi-trait analysis); TGCT cis rs7727544 0.716 rs2089855 chr5:131573529 A/G cg22598563 chr5:131563921 P4HA2 -0.31 -4.79 -0.39 4.73e-6 Blood metabolite levels; TGCT cis rs6570726 0.599 rs426371 chr6:145886469 A/G cg05347473 chr6:146136440 FBXO30 -0.62 -5.76 -0.46 6.15e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 1.000 rs36096931 chr6:86693134 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs11096990 0.634 rs1564710 chr4:39292798 G/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs7824557 0.585 rs2572382 chr8:11211302 T/G cg21775007 chr8:11205619 TDH 0.77 7.4 0.55 1.79e-11 Retinal vascular caliber; TGCT cis rs2594714 0.515 rs10411270 chr19:13940838 A/T cg18576835 chr19:13944261 NA -0.41 -5.25 -0.43 6.45e-7 Breast cancer; TGCT cis rs12926788 0.546 rs200537 chr16:24747787 G/C cg06028605 chr16:24865363 SLC5A11 -0.42 -4.69 -0.39 7.14e-6 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs939574 0.722 rs55951006 chr2:220132151 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.02 4.66 0.39 8.19e-6 Platelet distribution width; TGCT cis rs986417 1.000 rs3931460 chr14:60939101 A/C cg27398547 chr14:60952738 C14orf39 1.42 8.07 0.59 5.03e-13 Gut microbiota (bacterial taxa); TGCT cis rs7824557 0.767 rs4559208 chr8:11153925 C/G cg21775007 chr8:11205619 TDH 0.59 5.69 0.45 8.75e-8 Retinal vascular caliber; TGCT cis rs377070 0.934 rs309418 chr4:123623441 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.48 5.27 0.43 5.73e-7 Mosquito bite size; TGCT cis rs3757318 0.540 rs6900089 chr6:151851124 G/T cg18745416 chr6:152011399 ESR1 0.5 4.77 0.39 5.12e-6 Breast cancer (estrogen-receptor negative, progesterone-receptor negative, and human epidermal growth factor-receptor negative);Breast cancer; TGCT cis rs10876993 0.928 rs2640637 chr12:58077586 G/A cg15848620 chr12:58087721 OS9 -0.71 -5.77 -0.46 5.92e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs4285028 0.848 rs4118376 chr3:121636450 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.76 -6.49 -0.5 1.89e-9 Multiple sclerosis; TGCT cis rs1215050 0.546 rs7660713 chr4:98621341 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6933660 0.720 rs6936936 chr6:151753395 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.64 6.4 0.5 2.87e-9 Menarche (age at onset); TGCT cis rs8192284 0.965 rs4129267 chr1:154426264 C/T cg11650704 chr1:154556575 ADAR 0.25 4.46 0.37 1.81e-5 Fibrinogen;C-reactive protein;Fibrinogen levels; TGCT cis rs4642101 0.737 rs4447735 chr3:12825513 C/T cg05775895 chr3:12838266 CAND2 0.79 9.04 0.63 2.61e-15 QRS complex (12-leadsum); TGCT cis rs8180040 0.654 rs6791062 chr3:47174343 T/A cg27129171 chr3:47204927 SETD2 0.7 8.55 0.61 3.75e-14 Colorectal cancer; TGCT cis rs13242816 1.000 rs12706090 chr7:116104045 A/G cg16553024 chr7:116138462 CAV2 0.43 4.79 0.39 4.74e-6 P wave duration; TGCT cis rs9309473 0.660 rs10496192 chr2:73679866 T/C cg07208825 chr2:73871855 ALMS1P 0.25 4.53 0.38 1.34e-5 Metabolite levels; TGCT cis rs7949030 0.626 rs1061093 chr11:62334908 G/C cg22862634 chr11:62369728 EML3;MTA2 0.71 9.07 0.63 2.23e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7267979 0.933 rs2261109 chr20:25259200 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12627970 0.565 rs5757613 chr22:39715262 G/A cg17798944 chr22:39715225 SNORD43;RPL3 0.86 10.74 0.69 1.98e-19 Inflammatory bowel disease; TGCT trans rs12599106 0.792 rs76039834 chr16:34598453 G/A cg26668828 chr6:292823 DUSP22 -0.77 -8.12 -0.59 3.85e-13 Menopause (age at onset); TGCT cis rs1878931 0.501 rs4785934 chr16:3419934 G/T cg05754148 chr16:3507555 NAT15 -0.33 -4.46 -0.37 1.82e-5 Body mass index (adult); TGCT cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg13607699 chr17:42295918 UBTF -0.84 -7.72 -0.57 3.33e-12 Total body bone mineral density; TGCT cis rs3772130 1.000 rs3732408 chr3:121421179 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.85 0.4 3.66e-6 Cognitive performance; TGCT cis rs7666738 0.830 rs7680909 chr4:98934604 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs9376975 chr6:146355581 T/G cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2594989 0.943 rs2442785 chr3:11521828 C/T cg00170343 chr3:11313890 ATG7 0.7 5.22 0.42 7.17e-7 Circulating chemerin levels; TGCT cis rs931127 0.692 rs7934517 chr11:65445673 C/T cg27068330 chr11:65405492 SIPA1 -0.63 -6.18 -0.49 8.33e-9 Systemic lupus erythematosus; TGCT cis rs2760061 0.583 rs1636195 chr1:228211589 T/C cg02753203 chr1:228287806 NA 0.39 8.12 0.59 3.9e-13 Diastolic blood pressure; TGCT cis rs13315871 1.000 rs9869940 chr3:58401523 G/A cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs4664308 1.000 rs17831191 chr2:160911332 T/C cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs7904368 0.754 rs12253908 chr10:16853358 T/C cg14835575 chr10:16859367 RSU1 0.71 7.25 0.55 3.93e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs6448317 0.906 rs6448313 chr4:24905088 G/A cg21108841 chr4:24914750 CCDC149 0.68 5.58 0.45 1.43e-7 Heschl's gyrus morphology; TGCT cis rs9611565 0.559 rs132768 chr22:42013523 C/A cg06481639 chr22:41940642 POLR3H 0.74 6.64 0.51 8.88e-10 Vitiligo; TGCT cis rs3741151 0.892 rs7105681 chr11:73059341 G/A cg17517138 chr11:73019481 ARHGEF17 0.97 5.02 0.41 1.73e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs7772486 0.875 rs1331644 chr6:146398660 T/C cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.682 rs12046459 chr1:154912017 A/C cg16680214 chr1:154839983 KCNN3 -0.37 -7.66 -0.57 4.71e-12 Prostate cancer; TGCT cis rs798766 0.903 rs798726 chr4:1685211 C/T cg05874882 chr4:1763078 NA 0.36 4.83 0.4 3.87e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs7119038 0.818 rs2077579 chr11:118619047 T/G cg19308663 chr11:118741387 NA 0.29 5.39 0.44 3.41e-7 Sjögren's syndrome; TGCT cis rs7949030 0.653 rs2849030 chr11:62366986 G/A cg11742103 chr11:62369870 EML3;MTA2 -0.6 -8.74 -0.62 1.39e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1971762 0.545 rs7485472 chr12:54044438 T/C cg16917193 chr12:54089295 NA 1.07 11.4 0.72 4.81e-21 Height; TGCT cis rs7017914 0.905 rs1908035 chr8:71922408 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT trans rs4332037 0.539 rs11764590 chr7:2032803 C/T cg10840412 chr1:235813424 GNG4 0.93 6.69 0.51 6.97e-10 Bipolar disorder; TGCT cis rs1150668 0.796 rs213237 chr6:28323938 T/C cg13525197 chr6:28411240 ZSCAN23 -0.49 -4.68 -0.39 7.38e-6 Pubertal anthropometrics; TGCT cis rs7584330 0.737 rs6431540 chr2:238360966 T/C cg14458575 chr2:238380390 NA 0.47 7.48 0.56 1.17e-11 Prostate cancer; TGCT cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.28e-17 Electroencephalogram traits; TGCT cis rs9467603 0.920 rs34493019 chr6:25714959 A/G cg16898833 chr6:26189333 HIST1H4D 1.37 6.13 0.48 1.1e-8 Intelligence (multi-trait analysis); TGCT cis rs11096990 0.656 rs2066786 chr4:39302029 T/C cg20847110 chr4:39482781 LOC401127 0.16 4.65 0.39 8.26e-6 Cognitive function; TGCT cis rs2862064 1.000 rs7706978 chr5:156432566 T/C cg12943317 chr5:156479607 HAVCR1 -0.45 -5.77 -0.46 5.83e-8 Platelet count; TGCT cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg05738196 chr6:26577821 NA 0.87 11.5 0.72 2.82e-21 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.513 rs1596446 chr12:38282160 C/T cg13010199 chr12:38710504 ALG10B -0.59 -4.61 -0.38 9.88e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7267979 0.933 rs2258728 chr20:25276343 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7264396 0.676 rs6058380 chr20:34552900 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT trans rs2832077 0.527 rs9980449 chr21:30224889 G/C cg14791747 chr16:20752902 THUMPD1 1.09 12.67 0.75 4.09e-24 Cognitive test performance; TGCT cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg20887711 chr4:1340912 KIAA1530 0.77 6.49 0.5 1.89e-9 Longevity; TGCT cis rs78487399 0.808 rs7601039 chr2:43828637 C/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.71 5.07 0.41 1.44e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs1814175 0.765 rs11493326 chr11:50018063 T/C cg15704280 chr7:45808275 SEPT13 -0.71 -7.97 -0.58 8.91e-13 Height; TGCT trans rs916888 0.610 rs199530 chr17:44836653 C/T cg22968622 chr17:43663579 NA -0.96 -9.35 -0.64 4.62e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9467711 0.606 rs66827971 chr6:26365766 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7659604 1.000 rs6823488 chr4:122664819 A/G cg19748678 chr4:122722346 EXOSC9 0.56 5.35 0.43 4.14e-7 Type 2 diabetes; TGCT cis rs9921222 0.632 rs11649268 chr16:398643 A/C cg00101154 chr16:420108 MRPL28 -0.66 -7.69 -0.57 3.97e-12 Bone mineral density (spine);Bone mineral density; TGCT cis rs26868 0.742 rs26848 chr16:2263516 A/G cg10160842 chr16:2261107 C16orf79 -0.28 -4.69 -0.39 7.13e-6 Height; TGCT cis rs889312 0.500 rs866223 chr5:56125353 A/G cg24531977 chr5:56204891 C5orf35 -0.52 -5.48 -0.44 2.31e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs459571 0.606 rs457420 chr9:136909261 A/G cg13789015 chr9:136890014 NCRNA00094 -0.39 -6.77 -0.52 4.64e-10 Platelet distribution width; TGCT cis rs877282 1.000 rs12779159 chr10:772143 T/C cg17470449 chr10:769945 NA 0.3 4.68 0.39 7.39e-6 Uric acid levels; TGCT cis rs72945132 0.882 rs12274436 chr11:70132204 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs1035144 0.505 rs6574617 chr14:81457615 G/A cg06600135 chr14:81408086 NA -0.48 -4.49 -0.37 1.58e-5 Male sexual orientation; TGCT cis rs12210905 0.688 rs12215353 chr6:27407022 C/T cg08851530 chr6:28072375 NA 1.34 6.07 0.48 1.44e-8 Hip circumference adjusted for BMI; TGCT trans rs17685 0.725 rs4476928 chr7:75642107 C/A cg19862616 chr7:65841803 NCRNA00174 -0.5 -8.5 -0.61 5.01e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7044106 0.708 rs10984992 chr9:123473416 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.35 0.5 3.69e-9 Hip circumference adjusted for BMI; TGCT cis rs7918232 0.941 rs1753415 chr10:27395102 T/C cg14442939 chr10:27389572 ANKRD26 0.71 5.33 0.43 4.45e-7 Breast cancer; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg26668828 chr6:292823 DUSP22 -0.83 -8.57 -0.61 3.38e-14 Menopause (age at onset); TGCT cis rs7192750 0.538 rs28594331 chr16:71863482 C/T cg06353428 chr16:71660113 MARVELD3 0.84 7.44 0.56 1.44e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.95 -0.47 2.56e-8 Coronary artery disease; TGCT cis rs3733585 0.577 rs5014939 chr4:9953253 T/A cg11266682 chr4:10021025 SLC2A9 -0.57 -7.41 -0.55 1.69e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2932538 0.885 rs6693880 chr1:113110261 A/G cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs72627509 0.904 rs56281640 chr4:57765816 G/A cg26694713 chr4:57773883 REST 0.71 6.36 0.5 3.58e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3749237 0.636 rs1568662 chr3:49521263 A/G cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs4975616 0.869 rs452384 chr5:1330840 T/C cg07493874 chr5:1342172 CLPTM1L -0.28 -6.88 -0.53 2.69e-10 Lung cancer; TGCT cis rs7085104 0.727 rs12773892 chr10:104631177 G/A cg15744005 chr10:104629667 AS3MT -0.45 -4.52 -0.38 1.45e-5 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs1218582 0.741 rs10908446 chr1:154869559 G/A cg24250549 chr1:154909240 PMVK 0.64 6.26 0.49 5.86e-9 Prostate cancer; TGCT cis rs12477438 0.798 rs4850894 chr2:99629396 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs9682041 0.696 rs10936627 chr3:170104406 C/T cg11886554 chr3:170076028 SKIL 0.62 4.82 0.4 4.11e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs67460515 0.852 rs2404341 chr3:161092405 T/C cg03342759 chr3:160939853 NMD3 -0.52 -5.38 -0.44 3.56e-7 Parkinson's disease; TGCT cis rs57994353 0.600 rs10870163 chr9:139315594 G/A cg13741927 chr9:139327495 INPP5E -0.25 -5.59 -0.45 1.35e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs992157 0.735 rs2271541 chr2:219082119 G/T cg00012203 chr2:219082015 ARPC2 0.81 10.19 0.68 4.34e-18 Colorectal cancer; TGCT cis rs6938 0.534 rs12904897 chr15:75217686 A/G cg10253484 chr15:75165896 SCAMP2 -0.51 -4.66 -0.39 8.1e-6 Breast cancer; TGCT cis rs2172802 0.924 rs11941524 chr4:62446484 A/G cg04118610 chr4:62707027 LPHN3 -0.4 -4.64 -0.38 8.56e-6 Partial epilepsies; TGCT cis rs9534288 0.797 rs6561280 chr13:46583691 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs9911578 1.000 rs9907499 chr17:56949044 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs9814567 1.000 rs6439484 chr3:134249899 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -8.81 -0.62 9.26e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs514406 0.505 rs6688064 chr1:53165609 C/T cg01802117 chr1:53393560 SCP2 -0.42 -4.84 -0.4 3.86e-6 Monocyte count; TGCT cis rs9611565 0.921 rs5758297 chr22:41720697 A/G cg06634786 chr22:41940651 POLR3H -0.62 -5.93 -0.47 2.82e-8 Vitiligo; TGCT cis rs2710642 0.927 rs2539980 chr2:63208460 T/C cg17519650 chr2:63277830 OTX1 0.64 6.07 0.48 1.47e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs9560113 1.000 rs9555812 chr13:112181535 A/G cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs9467711 0.790 rs35400317 chr6:26593275 C/T cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9467773 0.549 rs9461273 chr6:26584526 A/G cg15659132 chr6:26577336 NA -0.84 -10.59 -0.69 4.57e-19 Intelligence (multi-trait analysis); TGCT cis rs41271951 0.512 rs115968379 chr1:151050087 A/C cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs881375 0.933 rs10818485 chr9:123667816 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.06 0.41 1.49e-6 Rheumatoid arthritis; TGCT cis rs11718455 0.960 rs11921995 chr3:44017301 C/A cg08738300 chr3:44038990 NA 0.87 6.63 0.51 9.07e-10 Coronary artery disease; TGCT cis rs453301 0.686 rs13252797 chr8:8861430 A/G cg11995313 chr8:8860691 ERI1 -0.53 -4.5 -0.37 1.55e-5 Joint mobility (Beighton score); TGCT cis rs1451375 1.000 rs2329340 chr7:50620229 C/T cg18232548 chr7:50535776 DDC 0.44 6.59 0.51 1.11e-9 Malaria; TGCT trans rs2288327 0.643 rs16866334 chr2:179336672 A/G cg14011486 chr1:26737247 LIN28 1.05 8.23 0.59 2.24e-13 Atrial fibrillation; TGCT trans rs66573146 1.000 rs6838042 chr4:6973049 G/T cg07817883 chr1:32538562 TMEM39B 1.6 7.9 0.58 1.28e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs2836974 0.863 rs6517519 chr21:40540245 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.49 0.65 2.19e-16 Cognitive function; TGCT cis rs17376456 0.877 rs34184666 chr5:93444584 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs9467603 1.000 rs9467603 chr6:25803712 A/G cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs3892630 0.878 rs8108621 chr19:33183291 G/A cg22980127 chr19:33182716 NUDT19 0.72 5.11 0.42 1.16e-6 Red blood cell traits; TGCT cis rs9894429 0.646 rs7406825 chr17:79619188 C/T cg18240062 chr17:79603768 NPLOC4 0.56 4.88 0.4 3.15e-6 Eye color traits; TGCT cis rs10782582 0.609 rs112205173 chr1:76310100 C/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs6700896 0.500 rs4655556 chr1:66080563 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs34172651 0.517 rs34172679 chr16:24840381 C/T cg06028605 chr16:24865363 SLC5A11 0.41 4.46 0.37 1.82e-5 Intelligence (multi-trait analysis); TGCT cis rs9427116 0.740 rs11264230 chr1:154608418 G/T cg17218026 chr1:154582156 ADAR 0.28 7.02 0.53 1.3e-10 Blood protein levels; TGCT cis rs4925386 0.959 rs4925385 chr20:60920624 A/G cg06026331 chr20:60912101 LAMA5 -0.3 -5.5 -0.44 2.12e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs12908161 1.000 rs35726233 chr15:85337800 C/T cg11189052 chr15:85197271 WDR73 0.71 5.87 0.47 3.68e-8 Schizophrenia; TGCT cis rs6500602 0.682 rs3761679 chr16:4457907 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 5.17 0.42 9.28e-7 Schizophrenia; TGCT cis rs3008870 1.000 rs3008870 chr1:67418027 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.91 0.73 2.83e-22 Lymphocyte percentage of white cells; TGCT cis rs67311347 0.524 rs11129869 chr3:40259738 G/A cg13683864 chr3:40499215 RPL14 -0.79 -7.39 -0.55 1.93e-11 Renal cell carcinoma; TGCT cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg23708337 chr7:1209742 NA 0.57 5.14 0.42 1.02e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6840360 0.642 rs12647555 chr4:152401098 A/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs1635 0.826 rs79567170 chr6:28280057 C/T cg15743358 chr6:28303923 ZNF323 -1.34 -5.96 -0.47 2.44e-8 Schizophrenia; TGCT cis rs4253772 0.550 rs6008729 chr22:46727428 C/G cg24881330 chr22:46731750 TRMU -0.75 -5.59 -0.45 1.38e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg22963979 chr7:1858916 MAD1L1 0.35 5.49 0.44 2.2e-7 Bipolar disorder and schizophrenia; TGCT cis rs2299587 0.554 rs3853530 chr8:17748420 C/T cg01800426 chr8:17659068 MTUS1 -0.57 -5.08 -0.42 1.33e-6 Economic and political preferences; TGCT cis rs8067545 0.750 rs9915758 chr17:19964775 A/G cg13482628 chr17:19912719 NA 0.54 4.64 0.38 8.78e-6 Schizophrenia; TGCT cis rs11148252 0.508 rs1886542 chr13:52706281 A/C cg00495681 chr13:53174319 NA 0.57 5.87 0.47 3.78e-8 Lewy body disease; TGCT cis rs2742417 0.603 rs1962800 chr3:45779943 C/T cg04837898 chr3:45731254 SACM1L -0.66 -7.06 -0.54 1.05e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs35934224 0.891 rs34249993 chr22:19872170 G/T cg11182965 chr22:19864308 TXNRD2 -0.36 -5.03 -0.41 1.67e-6 Glaucoma (primary open-angle); TGCT cis rs9300255 0.544 rs1727309 chr12:123658258 A/G cg00376283 chr12:123451042 ABCB9 0.74 5.08 0.42 1.32e-6 Neutrophil percentage of white cells; TGCT cis rs7191439 0.728 rs8043924 chr16:88787704 G/C cg27087555 chr16:88793112 FAM38A -0.45 -5.3 -0.43 5.01e-7 Plateletcrit; TGCT cis rs10423674 0.526 rs34482977 chr19:18824038 C/G cg20185461 chr19:18899082 COMP -0.53 -5.03 -0.41 1.68e-6 Menarche (age at onset); TGCT cis rs910187 0.641 rs6066232 chr20:45818905 C/T cg27589058 chr20:45804311 EYA2 -0.35 -7.32 -0.55 2.76e-11 Migraine; TGCT cis rs1008375 0.618 rs6842764 chr4:17568420 C/T cg10189774 chr4:17578691 LAP3 -0.6 -5.08 -0.42 1.35e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9650657 0.771 rs4240670 chr8:10665848 T/A cg27411982 chr8:10470053 RP1L1 -0.23 -5.17 -0.42 9.17e-7 Neuroticism; TGCT cis rs3806843 0.576 rs155359 chr5:140315425 G/T cg07102913 chr5:140593443 PCDHB13 -0.48 -4.77 -0.39 5.15e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs10791323 0.569 rs2257004 chr11:133712473 C/T cg03690763 chr11:133734501 NA -0.31 -4.82 -0.4 4.08e-6 Childhood ear infection; TGCT cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg20607798 chr8:58055168 NA 0.54 5.94 0.47 2.65e-8 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg27535305 chr1:53392650 SCP2 -0.27 -5.47 -0.44 2.39e-7 Monocyte count; TGCT cis rs11031096 0.803 rs6578454 chr11:4173384 A/G cg18678763 chr11:4115507 RRM1 0.39 5.28 0.43 5.52e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs35883536 0.528 rs1577512 chr1:101030832 G/A cg10298815 chr1:101004474 GPR88 0.25 4.68 0.39 7.46e-6 Monocyte count; TGCT cis rs10464366 0.746 rs4723822 chr7:39141613 C/T cg15212455 chr7:39170539 POU6F2 0.26 5.62 0.45 1.19e-7 IgG glycosylation; TGCT trans rs916888 0.773 rs199445 chr17:44817408 C/T cg22433210 chr17:43662623 NA 1.04 7.37 0.55 2.07e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2070488 1.000 rs4147024 chr3:38456664 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 9.06e-17 Electrocardiographic conduction measures; TGCT cis rs1005277 0.579 rs1614236 chr10:38502996 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.32 -0.6 1.33e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9357506 1.000 rs6910610 chr6:46307337 C/A cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs7819412 0.618 rs10105377 chr8:10975733 A/G cg21775007 chr8:11205619 TDH -0.52 -4.97 -0.41 2.13e-6 Triglycerides; TGCT cis rs9790314 1.000 rs336570 chr3:161072054 A/G cg03342759 chr3:160939853 NMD3 0.43 4.45 0.37 1.89e-5 Morning vs. evening chronotype; TGCT cis rs1215050 0.547 rs9999993 chr4:98562671 T/A cg05340658 chr4:99064831 C4orf37 -0.38 -4.53 -0.38 1.36e-5 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8072100 0.790 rs3760371 chr17:45695914 T/C cg10024583 chr17:45772800 TBKBP1 -0.43 -4.47 -0.37 1.76e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg00149659 chr3:10157352 C3orf10 1.0 6.43 0.5 2.45e-9 Alzheimer's disease; TGCT cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg06634786 chr22:41940651 POLR3H -0.85 -7.8 -0.57 2.16e-12 Vitiligo; TGCT cis rs7666738 0.830 rs13149779 chr4:99010145 G/T cg17366294 chr4:99064904 C4orf37 0.72 7.37 0.55 2.13e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs62103177 0.584 rs9956207 chr18:77968392 A/G cg05926928 chr17:57297772 GDPD1 -0.76 -6.88 -0.53 2.61e-10 Opioid sensitivity; TGCT cis rs556990 0.570 rs5960 chr13:113801737 C/T cg18105134 chr13:113819100 PROZ 0.45 7.35 0.55 2.35e-11 Blood protein levels; TGCT cis rs2594989 0.943 rs6442251 chr3:11417477 A/G cg00170343 chr3:11313890 ATG7 0.64 4.89 0.4 3.04e-6 Circulating chemerin levels; TGCT cis rs308403 0.600 rs376131 chr4:123629225 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.59 5.8 0.46 5.1e-8 Blood protein levels; TGCT cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs2276314 1.000 rs62101367 chr18:33550884 C/T cg05985134 chr18:33552581 C18orf21 0.55 4.84 0.4 3.76e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs9921338 0.924 rs7193645 chr16:11381036 A/G cg00044050 chr16:11439710 C16orf75 -0.87 -6.25 -0.49 5.97e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs6882046 0.513 rs679232 chr5:88054763 A/C cg22951263 chr5:87985283 NA 0.59 6.4 0.5 2.87e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs6570726 0.935 rs585292 chr6:145862228 T/C cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs10017201 chr4:98983561 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg03806693 chr22:41940476 POLR3H -1.13 -13.24 -0.77 1.73e-25 Vitiligo; TGCT cis rs11673344 0.523 rs6510584 chr19:37549601 G/C cg08039142 chr19:36980659 ZNF566 0.5 4.64 0.38 8.58e-6 Obesity-related traits; TGCT cis rs992157 0.710 rs12612347 chr2:219057338 C/T cg00012203 chr2:219082015 ARPC2 -0.82 -10.43 -0.68 1.14e-18 Colorectal cancer; TGCT cis rs7715806 0.500 rs17649248 chr5:74998426 C/T cg19683494 chr5:74908142 NA 0.53 4.85 0.4 3.67e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs986417 1.000 rs7159212 chr14:61068725 T/C cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs7917772 0.604 rs7908249 chr10:104373300 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13217239 0.585 rs114919438 chr6:26963792 T/C cg15659132 chr6:26577336 NA -0.61 -6.24 -0.49 6.24e-9 Schizophrenia; TGCT cis rs1577917 0.655 rs9359658 chr6:86305769 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.53 4.91 0.4 2.84e-6 Response to antipsychotic treatment; TGCT cis rs9916302 0.706 rs2879259 chr17:37410892 C/G cg07936489 chr17:37558343 FBXL20 -0.84 -6.16 -0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.679 rs2317991 chr8:58035080 C/T cg08280861 chr8:58055591 NA -0.34 -4.94 -0.41 2.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs7104764 1.000 rs1533825 chr11:214163 G/A cg18336825 chr11:236787 PSMD13;SIRT3 -1.02 -10.54 -0.69 6.26e-19 Menarche (age at onset); TGCT cis rs597539 0.652 rs488363 chr11:68658298 C/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.13 0.59 3.82e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10493773 0.609 rs2389972 chr1:86190666 A/G cg17807903 chr1:86174739 ZNHIT6 -0.5 -7.73 -0.57 3.23e-12 Urate levels in overweight individuals; TGCT cis rs9467773 1.000 rs10946835 chr6:26533757 C/T cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs56291770 chr3:40515370 T/C cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs6964587 1.000 rs6465347 chr7:91693837 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs1218582 0.741 rs11264281 chr1:154867221 A/G cg16680214 chr1:154839983 KCNN3 -0.43 -9.34 -0.64 4.93e-16 Prostate cancer; TGCT cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg06634786 chr22:41940651 POLR3H 0.73 6.81 0.52 3.84e-10 Vitiligo; TGCT cis rs4891159 0.790 rs1056714 chr18:74149526 A/G cg24786174 chr18:74118243 ZNF516 -0.54 -7.2 -0.54 5.09e-11 Longevity; TGCT cis rs12621445 1 rs12621445 chr2:24154964 C/T cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Immature fraction of reticulocytes; TGCT cis rs5769765 0.862 rs138856 chr22:50199378 G/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.07 -10.91 -0.7 7.73e-20 Schizophrenia; TGCT trans rs1814175 0.645 rs1851869 chr11:49960552 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs2235642 0.821 rs2281234 chr16:1602938 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.31 -5.23 -0.43 7.02e-7 Coronary artery disease; TGCT cis rs6921919 0.583 rs1124131 chr6:28380248 A/C cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1903068 0.925 rs1551645 chr4:55994314 T/G cg01777861 chr4:56023843 NA 0.56 6.43 0.5 2.54e-9 Endometriosis; TGCT cis rs926938 0.584 rs1286561 chr1:115375428 T/C cg12756093 chr1:115239321 AMPD1 -0.41 -6.02 -0.48 1.84e-8 Autism; TGCT cis rs6866344 0.697 rs11739893 chr5:178127837 G/A cg10224037 chr5:178157518 ZNF354A 0.93 7.9 0.58 1.26e-12 Neutrophil percentage of white cells; TGCT cis rs938554 0.513 rs1014290 chr4:10001861 G/A cg02734326 chr4:10020555 SLC2A9 0.46 4.69 0.39 6.98e-6 Blood metabolite levels; TGCT trans rs7618501 0.571 rs2240329 chr3:50107512 G/A cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs909002 0.925 rs7524405 chr1:32108579 A/C cg13919466 chr1:32135498 COL16A1 0.33 4.7 0.39 6.76e-6 Intelligence (multi-trait analysis); TGCT cis rs9790314 0.601 rs1450519 chr3:161094930 A/G cg03342759 chr3:160939853 NMD3 -0.39 -4.51 -0.38 1.48e-5 Morning vs. evening chronotype; TGCT cis rs11203032 0.831 rs12219735 chr10:90922890 C/T cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs8017423 0.904 rs12433417 chr14:90804028 A/G cg04374321 chr14:90722782 PSMC1 -0.74 -7.13 -0.54 7.15e-11 Mortality in heart failure; TGCT cis rs6424115 0.790 rs72874118 chr1:24177800 A/G cg15997130 chr1:24165203 NA -0.89 -10.18 -0.67 4.6e-18 Immature fraction of reticulocytes; TGCT cis rs853679 0.546 rs200952 chr6:27836976 C/T cg10876282 chr6:28092338 ZSCAN16 0.75 4.45 0.37 1.88e-5 Depression; TGCT cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs514406 0.830 rs533935 chr1:53308807 T/C cg22166914 chr1:53195759 ZYG11B 0.39 6.39 0.5 3.1e-9 Monocyte count; TGCT trans rs9329221 0.592 rs7832708 chr8:10190040 C/T cg15556689 chr8:8085844 FLJ10661 0.72 6.75 0.52 5.17e-10 Neuroticism; TGCT cis rs10779751 0.762 rs6671083 chr1:11325910 A/G cg08854313 chr1:11322531 MTOR -0.84 -9.56 -0.65 1.46e-16 Body mass index; TGCT cis rs2204008 0.653 rs11182569 chr12:38572452 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.18 0.42 8.83e-7 Bladder cancer; TGCT cis rs1005224 0.927 rs8007792 chr14:76175666 C/A cg25116370 chr14:76127843 TTLL5;C14orf1 -0.61 -4.91 -0.4 2.79e-6 Large artery stroke; TGCT cis rs7822232 0.908 rs1127096 chr8:145140472 A/G cg26272248 chr8:145163034 KIAA1875 -0.49 -4.81 -0.4 4.24e-6 Blood metabolite levels; TGCT cis rs854765 0.506 rs7210400 chr17:17949957 C/T cg04398451 chr17:18023971 MYO15A 0.33 5.37 0.43 3.76e-7 Total body bone mineral density; TGCT cis rs9640161 0.742 rs2159236 chr7:150017214 A/G cg10018233 chr7:150070692 REPIN1 0.33 4.78 0.39 4.89e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.86 0.4 3.51e-6 Lymphocyte counts; TGCT cis rs5417 0.761 rs6503010 chr17:7180435 C/T cg25256661 chr17:7137939 DVL2 -0.7 -6.99 -0.53 1.52e-10 Diastolic blood pressure; TGCT cis rs7246657 0.722 rs954504 chr19:38045394 A/G cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs651907 0.513 rs34963630 chr3:101504817 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs4699052 0.927 rs1870888 chr4:104169326 G/C cg16532752 chr4:104119610 CENPE -0.6 -5.61 -0.45 1.28e-7 Testicular germ cell tumor; TGCT cis rs9486715 0.867 rs9384628 chr6:96960232 T/C cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs9436747 0.803 rs1751485 chr1:66020219 C/A cg14976592 chr1:65886160 LEPROT;LEPR -0.5 -4.71 -0.39 6.48e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs1552244 0.765 rs17050675 chr3:10027686 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.44 -6.38 -0.5 3.16e-9 Alzheimer's disease; TGCT cis rs2305707 0.867 rs34258629 chr15:51555500 T/C cg19946085 chr15:51559439 CYP19A1 0.48 5.05 0.41 1.53e-6 Height; TGCT cis rs801193 1.000 rs6958520 chr7:66151453 T/C cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs12983728 0.831 rs35081008 chr19:58662235 C/T cg07378217 chr19:58662286 ZNF329 -0.9 -5.1 -0.42 1.25e-6 Cholesterol, total; TGCT cis rs61935443 0.832 rs11107771 chr12:95276844 A/G cg21533806 chr12:95267307 NA 0.52 4.54 0.38 1.31e-5 Schizophrenia; TGCT cis rs17376456 0.877 rs10514380 chr5:93409370 C/T cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT trans rs4650994 0.525 rs11806608 chr1:178511375 T/C cg05059571 chr16:84539110 KIAA1609 -0.55 -11.51 -0.72 2.72e-21 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4819052 0.851 rs35560973 chr21:46662573 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 6.24 0.49 6.33e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10193935 0.901 rs2118889 chr2:42451683 G/T cg27598129 chr2:42591480 NA -0.36 -4.78 -0.39 4.78e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs56399783 0.614 rs73047368 chr7:2766396 G/T cg19731401 chr7:2775893 GNA12 0.38 5.36 0.43 3.93e-7 Childhood ear infection; TGCT cis rs2046867 0.862 rs62251653 chr3:72811827 C/T cg25664220 chr3:72788482 NA -0.57 -7.06 -0.54 1.06e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs11719291 0.833 rs34037363 chr3:48821036 C/T cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 Cognitive function; TGCT cis rs644799 1.000 rs1784135 chr11:95531748 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3111414 1.000 rs3111414 chr2:8443859 C/G cg10367409 chr2:8711177 NA -0.2 -4.58 -0.38 1.11e-5 Itch intensity from mosquito bite; TGCT cis rs8033133 0.602 rs4906699 chr15:25321029 A/G cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 0.24 4.65 0.39 8.33e-6 Blood osmolality (transformed sodium); TGCT cis rs9303401 0.614 rs62084384 chr17:57126842 G/A cg25039879 chr17:56429692 SUPT4H1 0.54 4.84 0.4 3.85e-6 Cognitive test performance; TGCT cis rs854765 0.583 rs8080823 chr17:17864048 T/C cg09796270 chr17:17721594 SREBF1 0.26 5.31 0.43 4.88e-7 Total body bone mineral density; TGCT cis rs7647973 0.559 rs9586 chr3:49213637 C/T cg05785598 chr3:49045655 WDR6 0.44 5.12 0.42 1.15e-6 Menarche (age at onset); TGCT cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs7772486 0.790 rs9390365 chr6:146235626 A/G cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs4746818 1.000 rs9299502 chr10:70876934 C/T cg04149295 chr10:70884716 VPS26A 0.76 5.33 0.43 4.49e-7 Left atrial antero-posterior diameter; TGCT cis rs72781680 1.000 rs72796326 chr2:24137047 G/A cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs763014 0.931 rs1981483 chr16:630665 G/A cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg10047753 chr17:41438598 NA -0.93 -9.16 -0.64 1.35e-15 Menopause (age at onset); TGCT cis rs1552244 1.000 rs113134644 chr3:10086286 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.63 -0.51 9.16e-10 Alzheimer's disease; TGCT cis rs696279 0.869 rs697509 chr7:16700495 G/A cg16702815 chr7:16920271 AGR3 0.27 4.51 0.38 1.47e-5 Mean platelet volume; TGCT cis rs875971 0.964 rs160635 chr7:65528918 T/C cg18876405 chr7:65276391 NA 0.32 4.86 0.4 3.49e-6 Aortic root size; TGCT cis rs4478037 0.822 rs77355992 chr3:33107518 T/C cg19404215 chr3:33155277 CRTAP 1.24 5.97 0.47 2.36e-8 Major depressive disorder; TGCT cis rs916888 0.821 rs199513 chr17:44856932 A/G cg15921436 chr17:44337874 NA -0.42 -5.88 -0.47 3.48e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs597539 0.652 rs478647 chr11:68700424 C/T cg21963583 chr11:68658836 MRPL21 0.35 5.8 0.46 5.09e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12477438 0.748 rs10200974 chr2:99675227 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs9473924 0.542 rs9463665 chr6:50928520 G/T cg14470998 chr6:50812995 TFAP2B 1.26 7.3 0.55 3.1e-11 Body mass index; TGCT cis rs377070 0.934 rs309397 chr4:123614323 A/C cg10495464 chr4:123653540 BBS12;LOC729338 0.46 5.1 0.42 1.25e-6 Mosquito bite size; TGCT cis rs9926296 0.715 rs2115401 chr16:89740609 A/G cg01097406 chr16:89675127 NA -0.31 -5.49 -0.44 2.2e-7 Vitiligo; TGCT cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg24549020 chr5:56110836 MAP3K1 -0.67 -5.78 -0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs2847297 1.000 rs6505765 chr18:12782849 C/G cg23598886 chr18:12777645 NA -0.41 -4.81 -0.4 4.28e-6 Rheumatoid arthritis; TGCT cis rs3858526 1.000 rs3858526 chr11:5959757 A/C cg05234568 chr11:5960015 NA -0.44 -4.49 -0.37 1.61e-5 DNA methylation (variation); TGCT cis rs2439831 0.850 rs7183809 chr15:44120868 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT cis rs4919694 0.611 rs76695159 chr10:105070837 C/T cg04362960 chr10:104952993 NT5C2 0.91 6.05 0.48 1.59e-8 Arsenic metabolism; TGCT cis rs2115630 0.936 rs6496318 chr15:85215229 C/T cg12863693 chr15:85201151 NMB -0.34 -4.73 -0.39 5.96e-6 P wave terminal force; TGCT cis rs3824867 0.920 rs9919526 chr11:47451623 C/T cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs8038465 0.662 rs7497012 chr15:73968719 G/A cg15420318 chr15:73925796 NPTN 0.7 7.49 0.56 1.15e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs910187 0.605 rs6063080 chr20:45805091 G/A cg27589058 chr20:45804311 EYA2 -0.4 -8.9 -0.62 5.75e-15 Migraine; TGCT trans rs4650994 0.935 rs12039531 chr1:178515612 G/A cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.33e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs921968 0.541 rs514356 chr2:219375018 C/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs9311474 0.652 rs352158 chr3:52217704 C/T cg10802521 chr3:52805072 NEK4 -0.6 -6.64 -0.51 8.67e-10 Electroencephalogram traits; TGCT cis rs2204008 0.623 rs1607878 chr12:38376000 A/G cg26384229 chr12:38710491 ALG10B 0.76 6.89 0.53 2.46e-10 Bladder cancer; TGCT cis rs244731 0.959 rs11740250 chr5:176721272 G/C cg06060754 chr5:176797920 RGS14 0.46 6.42 0.5 2.66e-9 Urate levels in lean individuals; TGCT cis rs798766 1.000 rs1665364 chr4:1727206 A/G cg05874882 chr4:1763078 NA 0.36 4.87 0.4 3.27e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs4975616 0.804 rs381949 chr5:1322468 G/A cg07493874 chr5:1342172 CLPTM1L -0.27 -6.69 -0.51 6.91e-10 Lung cancer; TGCT cis rs12541335 0.639 rs68063696 chr8:22153236 A/G cg09517075 chr8:22133004 PIWIL2 0.24 4.57 0.38 1.17e-5 Hypertriglyceridemia; TGCT cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg11502198 chr6:26597334 ABT1 0.55 4.89 0.4 3.05e-6 Intelligence (multi-trait analysis); TGCT cis rs7786808 0.778 rs34212455 chr7:158224490 C/T cg01191920 chr7:158217561 PTPRN2 -0.39 -5.89 -0.47 3.32e-8 Obesity-related traits; TGCT cis rs12620999 0.941 rs4663240 chr2:238036632 G/T cg23555395 chr2:238036564 NA -0.31 -5.51 -0.44 2.02e-7 Systemic lupus erythematosus; TGCT cis rs10992471 0.603 rs4744141 chr9:95352140 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.71 -0.46 7.82e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs17221829 0.528 rs4561217 chr11:89375265 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs11671005 0.735 rs56290606 chr19:58919320 A/G cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT cis rs5758265 1 rs5758265 chr22:41617897 G/A cg03806693 chr22:41940476 POLR3H -0.65 -6.22 -0.49 6.86e-9 Depressive symptoms (multi-trait analysis); TGCT trans rs1814175 0.817 rs4881648 chr11:49812901 A/G cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg12310025 chr6:25882481 NA 0.9 8.89 0.62 5.87e-15 Blood metabolite levels; TGCT trans rs2727020 0.688 rs2734002 chr11:49234162 A/G cg03929089 chr4:120376271 NA 0.71 7.84 0.58 1.79e-12 Coronary artery disease; TGCT cis rs1997103 0.871 rs6956733 chr7:55393032 A/C cg17469321 chr7:55412551 NA 0.58 5.18 0.42 8.69e-7 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg10862848 chr6:42927986 GNMT -0.39 -4.7 -0.39 6.86e-6 Plasma homocysteine levels (post-methionine load test); TGCT cis rs7727544 0.788 rs270613 chr5:131640583 A/G cg24060327 chr5:131705240 SLC22A5 -0.57 -6.15 -0.48 9.79e-9 Blood metabolite levels; TGCT cis rs7147624 1.000 rs7150233 chr14:66200816 A/G cg03016385 chr14:66212404 NA -0.5 -7.04 -0.53 1.13e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs8111998 0.826 rs10421335 chr19:22768105 G/A cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT trans rs1499614 1.000 rs2659913 chr7:66157336 T/A cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs11690462 0.963 rs11674089 chr2:26587076 G/A cg04726446 chr2:26624865 C2orf39 0.43 4.64 0.38 8.58e-6 Coronary artery disease; TGCT cis rs10791097 0.694 rs61910787 chr11:130744473 G/A cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10791323 0.569 rs10750542 chr11:133713436 T/C cg15485101 chr11:133734466 NA 0.39 5.18 0.42 8.85e-7 Childhood ear infection; TGCT cis rs1775715 0.707 rs2808081 chr10:32162342 C/T cg14930904 chr10:32216787 ARHGAP12 -0.5 -4.73 -0.39 6.06e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs1801251 0.896 rs6719061 chr2:233695885 C/T cg25237894 chr2:233734115 C2orf82 -0.29 -5.41 -0.44 3.14e-7 Coronary artery disease; TGCT cis rs3087591 0.960 rs2905787 chr17:29482381 G/A cg24425628 chr17:29625626 OMG;NF1 0.43 6.39 0.5 3.07e-9 Hip circumference; TGCT cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 14.32 0.79 4.83e-28 Prudent dietary pattern; TGCT cis rs6589563 0.609 rs56225305 chr11:116625362 G/A cg20660624 chr11:117307972 DSCAML1 -0.38 -4.99 -0.41 2.02e-6 Eosinophil counts; TGCT cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg16497277 chr3:49208875 KLHDC8B -0.53 -5.12 -0.42 1.13e-6 Menarche (age at onset); TGCT cis rs9902453 0.933 rs9908901 chr17:28469713 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs1555895 0.543 rs1555898 chr10:853783 T/C cg02193355 chr10:851439 NA 0.2 4.54 0.38 1.3e-5 Survival in rectal cancer; TGCT trans rs7618501 0.933 rs3811695 chr3:49761613 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs4285028 0.747 rs6791882 chr3:121373058 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.33 -0.55 2.54e-11 Multiple sclerosis; TGCT cis rs3796619 1.000 rs3796619 chr4:1095281 A/G cg27284194 chr4:1044797 NA 0.47 4.57 0.38 1.17e-5 Recombination rate (males); TGCT cis rs6089584 0.526 rs6089316 chr20:60627552 C/T cg06108461 chr20:60628389 TAF4 -0.42 -5.1 -0.42 1.24e-6 Body mass index; TGCT cis rs6087990 0.735 rs2064350 chr20:31390533 T/C cg13636640 chr20:31349939 DNMT3B 0.95 12.3 0.74 3.25e-23 Ulcerative colitis; TGCT cis rs1008375 0.966 rs4698619 chr4:17580955 G/A cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9513593 1.000 rs9585019 chr13:99850487 T/C cg21788972 chr13:99853209 UBAC2 0.61 4.96 0.41 2.24e-6 Psoriasis; TGCT cis rs17767294 0.614 rs72849222 chr6:28202354 G/T cg08851530 chr6:28072375 NA 1.46 6.76 0.52 4.79e-10 Parkinson's disease; TGCT cis rs12477438 0.765 rs10193039 chr2:99692373 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.59 -5.03 -0.41 1.71e-6 Chronic sinus infection; TGCT cis rs12971120 0.947 rs4891559 chr18:72170397 C/T cg25817165 chr18:72167213 CNDP2 -0.29 -5.51 -0.44 1.98e-7 Refractive error; TGCT cis rs6740322 0.895 rs11684601 chr2:43574242 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -5.93 -0.47 2.87e-8 Coronary artery disease; TGCT cis rs4824093 0.610 rs77128035 chr22:50241024 C/T cg14114931 chr22:50943910 LMF2 0.37 4.61 0.38 9.67e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs12477438 0.798 rs2045057 chr2:99684929 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs7605378 0.528 rs281791 chr2:200850402 A/G cg19045956 chr2:200819837 C2orf60;C2orf47 -0.54 -5.88 -0.47 3.6e-8 Osteoporosis; TGCT cis rs2404602 0.716 rs12902174 chr15:76863540 T/C cg22467129 chr15:76604101 ETFA -0.44 -5.05 -0.41 1.51e-6 Blood metabolite levels; TGCT cis rs1420338 0.967 rs9655014 chr7:34148632 T/C cg01275685 chr7:34179230 BMPER -0.27 -4.84 -0.4 3.82e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs9303401 0.592 rs66583824 chr17:56639853 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs7937612 1.000 rs12417256 chr11:120337519 A/C cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.59 -0.38 1.07e-5 Intraocular pressure; TGCT cis rs1005277 0.579 rs2504143 chr10:38383706 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.2 -0.59 2.5e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4845570 0.834 rs7007 chr1:151735576 T/C cg07092448 chr1:151763213 TDRKH -1.05 -7.65 -0.57 4.72e-12 Coronary artery disease; TGCT cis rs208520 0.779 rs208446 chr6:66903515 T/C cg07460842 chr6:66804631 NA -0.9 -9.14 -0.63 1.54e-15 Exhaled nitric oxide output; TGCT cis rs9902453 0.904 rs11080115 chr17:28408070 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -7.98 -0.58 8.19e-13 Coffee consumption (cups per day); TGCT cis rs6540559 0.673 rs6694552 chr1:209976459 A/C cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs6582630 0.555 rs6582503 chr12:38557886 A/C cg26384229 chr12:38710491 ALG10B 0.89 8.14 0.59 3.55e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs12765878 0.580 rs4918058 chr10:105596641 G/C cg11005552 chr10:105648138 OBFC1 -0.39 -6.05 -0.48 1.58e-8 Coronary artery disease; TGCT cis rs477895 0.713 rs67546972 chr11:63962162 G/A cg04317338 chr11:64019027 PLCB3 0.79 6.5 0.5 1.77e-9 Mean platelet volume; TGCT cis rs6121246 0.529 rs58757492 chr20:30181425 G/A cg21427119 chr20:30132790 HM13 -0.43 -6.28 -0.49 5.3e-9 Mean corpuscular hemoglobin; TGCT cis rs1857353 1.000 rs111226767 chr1:75853959 C/A cg11838876 chr1:75668600 SLC44A5 -0.47 -4.54 -0.38 1.32e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs11785693 0.862 rs11786657 chr8:5001792 T/C cg26367366 chr8:4980734 NA 0.56 4.44 0.37 1.95e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs7666738 0.830 rs13138051 chr4:99050367 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs896854 0.654 rs896846 chr8:95972453 G/A cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.51e-14 Type 2 diabetes; TGCT cis rs908922 0.847 rs499697 chr1:152493154 A/G cg20991723 chr1:152506922 NA -0.42 -5.38 -0.43 3.62e-7 Hair morphology; TGCT cis rs72615157 0.634 rs74742883 chr7:99785765 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.6 -5.05 -0.41 1.54e-6 Lung function (FEV1/FVC); TGCT cis rs72781680 0.948 rs72796319 chr2:24133027 T/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs6912958 0.712 rs7755167 chr6:88338752 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs78487399 0.614 rs7600657 chr2:43710444 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -5.26 -0.43 6.23e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg12751644 chr20:60527061 NA 0.5 6.64 0.51 9.01e-10 Obesity-related traits; TGCT cis rs8013055 0.706 rs8003957 chr14:105971702 A/G cg23356831 chr14:105996513 TMEM121 0.41 6.22 0.49 6.83e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7617773 0.539 rs11130165 chr3:48384721 G/T cg11946769 chr3:48343235 NME6 0.57 4.83 0.4 4.01e-6 Coronary artery disease; TGCT cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6725041 0.547 rs6753945 chr2:213204574 T/C cg16329650 chr2:213403929 ERBB4 -0.67 -5.85 -0.47 4.03e-8 QT interval (ambient particulate matter interaction); TGCT cis rs875971 0.964 rs6945032 chr7:65922486 C/T cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs10992471 0.603 rs10761155 chr9:95153729 C/G cg14631576 chr9:95140430 CENPP -0.33 -4.96 -0.41 2.23e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3862260 0.905 rs3850870 chr1:120161037 C/T cg16322792 chr1:120165303 ZNF697 0.27 5.71 0.46 7.73e-8 Systemic lupus erythematosus; TGCT cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg02725872 chr8:58115012 NA -0.41 -4.95 -0.41 2.37e-6 Developmental language disorder (linguistic errors); TGCT cis rs568617 1.000 rs568617 chr11:65653242 C/T cg04055107 chr11:65626734 MUS81;CFL1 0.57 5.22 0.42 7.39e-7 Crohn's disease; TGCT cis rs8103278 0.507 rs10422883 chr19:46247641 A/G cg11657440 chr19:46296263 DMWD 0.75 7.74 0.57 3.02e-12 Coronary artery disease; TGCT cis rs9914544 0.524 rs8071147 chr17:18790678 A/G cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs7681440 0.626 rs2289515 chr4:90816790 T/A cg20003494 chr4:90757398 SNCA -0.54 -4.88 -0.4 3.21e-6 Dementia with Lewy bodies; TGCT cis rs2486012 0.737 rs246773 chr1:44300249 A/G cg12908607 chr1:44402522 ARTN -0.72 -5.68 -0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs2549003 0.811 rs10072700 chr5:131816903 A/C cg02551604 chr5:131831745 NA -0.76 -7.42 -0.55 1.65e-11 Asthma (sex interaction); TGCT trans rs1005277 0.557 rs176887 chr10:38406094 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs11098499 0.863 rs17050695 chr4:120489527 G/T cg09307838 chr4:120376055 NA 0.7 7.03 0.53 1.23e-10 Corneal astigmatism; TGCT cis rs2795502 0.554 rs1620395 chr10:43341185 G/A cg20628663 chr10:43360327 NA -0.35 -6.05 -0.48 1.57e-8 Blood protein levels; TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs7267979 0.966 rs2482948 chr20:25296499 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1729951 0.575 rs835641 chr3:136703474 G/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.24e-7 Neuroticism; TGCT cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg10802521 chr3:52805072 NEK4 -0.74 -9.02 -0.63 2.87e-15 Bipolar disorder; TGCT cis rs7954584 0.531 rs6486781 chr12:122318985 A/C cg22618164 chr12:122356400 WDR66 0.53 5.26 0.43 6.24e-7 Mean corpuscular volume; TGCT cis rs1215050 0.776 rs1627946 chr4:98844416 G/A cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.22e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9858542 0.953 rs6766131 chr3:49538932 T/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs854765 0.547 rs7223696 chr17:17915791 G/T cg09796270 chr17:17721594 SREBF1 0.25 5.03 0.41 1.71e-6 Total body bone mineral density; TGCT cis rs3125734 0.534 rs10821973 chr10:64052337 G/A cg19640130 chr10:64028056 RTKN2 -0.38 -4.79 -0.39 4.73e-6 Rheumatoid arthritis; TGCT cis rs2072499 0.778 rs41265025 chr1:156163906 C/T cg24450063 chr1:156163899 SLC25A44 1.1 10.15 0.67 5.42e-18 Testicular germ cell tumor; TGCT cis rs6840360 0.642 rs1443088 chr4:152450126 G/A cg17479576 chr4:152424074 FAM160A1 -0.57 -6.02 -0.48 1.85e-8 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.514 rs2979151 chr8:8258019 A/G cg15462221 chr8:8086144 FLJ10661 0.49 4.49 0.37 1.63e-5 Mood instability; TGCT cis rs7552404 0.924 rs1146588 chr1:76229787 C/G cg03433033 chr1:76189801 ACADM 0.75 8.76 0.62 1.19e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg03188948 chr7:1209495 NA 0.67 5.62 0.45 1.18e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2242116 0.796 rs4683296 chr3:46973820 G/C cg02527881 chr3:46936655 PTH1R 0.32 6.0 0.47 1.99e-8 Birth weight; TGCT cis rs7246657 0.722 rs12979640 chr19:38179156 T/C cg03611452 chr19:38183253 ZNF781 -0.62 -5.08 -0.41 1.37e-6 Coronary artery calcification; TGCT trans rs797680 0.856 rs11164902 chr1:93778794 A/G cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7551222 0.683 rs898386 chr1:204579697 A/G cg09150239 chr1:204347429 NA 0.49 4.93 0.41 2.55e-6 Schizophrenia; TGCT cis rs9916302 0.904 rs620686 chr17:37453617 A/G cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs9311474 1.000 rs7614727 chr3:52295895 C/T cg10802521 chr3:52805072 NEK4 -0.57 -6.19 -0.49 8.19e-9 Electroencephalogram traits; TGCT cis rs6163 0.727 rs284862 chr10:104572081 C/T cg05855489 chr10:104503620 C10orf26 -0.66 -6.23 -0.49 6.63e-9 Waist circumference;Hip circumference; TGCT cis rs2839186 0.739 rs2280958 chr21:47642016 C/T cg13732083 chr21:47605072 C21orf56 0.37 4.69 0.39 7.07e-6 Testicular germ cell tumor; TGCT cis rs6964587 0.626 rs68009402 chr7:91516226 G/A cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs1997103 1.000 rs6950311 chr7:55400990 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7193541 0.646 rs7188880 chr16:74664810 A/T cg01733217 chr16:74700730 RFWD3 0.96 13.17 0.76 2.62e-25 Multiple myeloma; TGCT cis rs2688608 0.934 rs2675679 chr10:75658581 C/T cg02947784 chr10:75434997 AGAP5 0.16 4.47 0.37 1.74e-5 Inflammatory bowel disease; TGCT cis rs9911578 0.835 rs9788975 chr17:56460800 G/A cg12560992 chr17:57184187 TRIM37 -0.73 -8.17 -0.59 3.05e-13 Intelligence (multi-trait analysis); TGCT cis rs950169 0.881 rs150965 chr15:85080527 T/G cg12863693 chr15:85201151 NMB 0.41 4.49 0.37 1.63e-5 Schizophrenia; TGCT cis rs72945132 0.882 rs60917762 chr11:70211384 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs12580194 0.593 rs7976828 chr12:55726450 A/T cg10672482 chr12:55725839 OR6C3 -0.56 -4.89 -0.4 3.1e-6 Cancer; TGCT cis rs6088590 0.523 rs6088536 chr20:33189106 T/C cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs10736390 0.640 rs10888858 chr1:55108978 A/G cg01517571 chr1:55089959 ACOT11;FAM151A -0.52 -10.89 -0.7 8.84e-20 Survival in pancreatic cancer; TGCT cis rs61990749 0.544 rs2544567 chr14:78181739 T/C cg02301378 chr14:78227641 SNW1;C14orf178 0.63 4.62 0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs314370 0.818 rs12705091 chr7:100472380 C/T cg10426581 chr7:100472382 SRRT 0.97 9.07 0.63 2.26e-15 Resting heart rate; TGCT cis rs7949030 0.626 rs11231154 chr11:62362293 A/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.48 0.65 2.35e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7089973 0.604 rs55759483 chr10:116573423 T/C cg03647239 chr10:116582469 FAM160B1 0.6 5.48 0.44 2.33e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs11264213 0.591 rs558120 chr1:36537640 T/C cg27506609 chr1:36549197 TEKT2 -0.32 -4.6 -0.38 1.02e-5 Schizophrenia; TGCT cis rs10791323 0.569 rs10750553 chr11:133740251 T/C cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs12135062 1.000 rs12135062 chr1:3103312 A/C cg00254258 chr1:3105189 PRDM16 0.34 5.66 0.45 9.74e-8 Migraine; TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs6665290 0.836 rs12593 chr1:227172290 A/G cg10327440 chr1:227177885 CDC42BPA 0.96 17.72 0.85 8.7e-36 Myeloid white cell count; TGCT cis rs5750830 0.649 rs2413590 chr22:39790191 G/C cg05872129 chr22:39784769 NA -1.02 -11.25 -0.71 1.17e-20 Intelligence (multi-trait analysis); TGCT cis rs10744422 0.925 rs3825143 chr12:123352179 C/T cg25930673 chr12:123319894 HIP1R -0.88 -5.28 -0.43 5.59e-7 Schizophrenia; TGCT cis rs8180040 0.764 rs11718795 chr3:47218727 G/A cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT cis rs681343 1.000 rs516246 chr19:49206172 C/T cg13540341 chr19:49222985 MAMSTR -0.33 -4.48 -0.37 1.69e-5 Lung adenocarcinoma;Primary sclerosing cholangitis;Childhood ear infection; TGCT cis rs763121 0.889 rs9610971 chr22:38910810 C/T cg06022373 chr22:39101656 GTPBP1 0.75 7.37 0.55 2.1e-11 Menopause (age at onset); TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg11965913 chr1:205819406 PM20D1 0.51 7.19 0.54 5.34e-11 Menarche (age at onset); TGCT cis rs6598955 0.724 rs10902737 chr1:26635716 G/A cg04990556 chr1:26633338 UBXN11 -0.92 -12.18 -0.74 6.18e-23 Obesity-related traits; TGCT cis rs477895 1.000 rs11600990 chr11:64082807 C/T cg04317338 chr11:64019027 PLCB3 0.71 5.65 0.45 1.05e-7 Mean platelet volume; TGCT cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs228437 0.586 rs9494011 chr6:134964580 T/A cg09872934 chr6:134495829 SGK1 -0.58 -4.74 -0.39 5.66e-6 Melanoma; TGCT cis rs778371 0.676 rs4973563 chr2:233716421 C/T cg08000102 chr2:233561755 GIGYF2 -0.69 -7.7 -0.57 3.75e-12 Schizophrenia; TGCT cis rs7296418 0.699 rs11057219 chr12:123750073 T/C cg00376283 chr12:123451042 ABCB9 0.73 6.44 0.5 2.36e-9 Platelet count; TGCT cis rs6690583 0.623 rs74761855 chr1:85432947 A/C cg20280350 chr1:85513789 MCOLN3 -0.68 -4.49 -0.37 1.6e-5 Serum sulfate level; TGCT cis rs7017914 0.967 rs17760497 chr8:71617045 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs929354 0.772 rs10230895 chr7:157007038 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.95 -0.63 4.3e-15 Body mass index; TGCT cis rs7666738 0.752 rs62318905 chr4:99036103 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs244731 0.959 rs918459 chr5:176669030 C/T cg06060754 chr5:176797920 RGS14 -0.44 -6.3 -0.49 4.81e-9 Urate levels in lean individuals; TGCT cis rs11651000 0.625 rs58067360 chr17:45819587 G/C cg06532163 chr17:45867833 NA 0.32 4.83 0.4 3.87e-6 IgG glycosylation; TGCT cis rs12477438 0.520 rs13035311 chr2:99717322 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs9868809 0.881 rs13324142 chr3:48669447 C/T cg00383909 chr3:49044727 WDR6 0.99 5.63 0.45 1.13e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs2839186 0.934 rs13049797 chr21:47707582 T/C cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs4523957 0.690 rs11867782 chr17:2090507 T/G cg16513277 chr17:2031491 SMG6 -0.2 -4.52 -0.38 1.42e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1552244 0.882 rs17050672 chr3:10025463 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 6.18 0.48 8.67e-9 Alzheimer's disease; TGCT cis rs12464483 0.591 rs4952171 chr2:30886903 G/A cg17749961 chr2:30669863 LCLAT1 0.67 5.05 0.41 1.56e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs9291683 0.546 rs7442336 chr4:10045783 G/A cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Bone mineral density; TGCT cis rs12701220 0.894 rs12539012 chr7:1052133 G/A cg07217954 chr7:1067459 C7orf50 -0.49 -4.76 -0.39 5.27e-6 Bronchopulmonary dysplasia; TGCT cis rs9534288 0.797 rs994351 chr13:46588194 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs10751667 0.643 rs7394524 chr11:933865 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs910316 0.737 rs175510 chr14:75524839 G/A cg11812906 chr14:75593930 NEK9 -0.61 -5.68 -0.45 9e-8 Height; TGCT cis rs7010267 0.602 rs1485307 chr8:120007395 T/C cg17171407 chr8:119960777 TNFRSF11B 0.25 4.46 0.37 1.85e-5 Total body bone mineral density (age 45-60); TGCT cis rs2562456 0.917 rs2681377 chr19:21716520 T/C cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg07424592 chr7:64974309 NA -0.61 -5.81 -0.46 5.06e-8 Calcium levels; TGCT cis rs739496 0.542 rs7316698 chr12:111790511 C/T cg10833066 chr12:111807467 FAM109A 0.44 7.52 0.56 9.58e-12 Platelet count; TGCT cis rs3784262 0.740 rs4646582 chr15:58307381 G/C cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.26 -0.49 5.67e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs13256369 1.000 rs7843488 chr8:8576217 C/T cg17143192 chr8:8559678 CLDN23 0.62 5.8 0.46 5.1e-8 Obesity-related traits; TGCT cis rs7666738 0.791 rs10017624 chr4:98984009 G/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12950390 0.776 rs4793646 chr17:45853966 A/C cg24803719 chr17:45855879 NA -0.5 -5.05 -0.41 1.51e-6 IgG glycosylation; TGCT trans rs1814175 0.817 rs7483795 chr11:49704930 G/A cg03929089 chr4:120376271 NA -0.71 -8.36 -0.6 1.09e-13 Height; TGCT cis rs58722170 0.659 rs55852308 chr1:38078630 A/T cg17933807 chr1:38061675 GNL2 -0.86 -8.69 -0.62 1.83e-14 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs1580019 0.563 rs896137 chr7:32579345 G/T cg07520158 chr7:32535189 LSM5;AVL9 0.6 4.95 0.41 2.39e-6 Cognitive ability; TGCT cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs12367572 0.504 rs1903937 chr12:45521487 C/T cg04608330 chr12:45269318 NELL2 -0.49 -4.55 -0.38 1.26e-5 Gut microbiome composition (summer); TGCT cis rs149026780 1 rs149026780 chr2:97881612 A/C cg26665480 chr2:98280029 ACTR1B -0.97 -4.85 -0.4 3.69e-6 Monocyte chemoattractant protein-3 levels; TGCT cis rs6570726 0.791 rs6902404 chr6:145905254 G/A cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT trans rs9951602 0.512 rs12455591 chr18:76656028 A/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.71 0.75 3.32e-24 Obesity-related traits; TGCT cis rs12188164 1.000 rs12188678 chr5:428231 T/C cg21144161 chr5:423903 AHRR 0.24 4.5 0.37 1.53e-5 Cystic fibrosis severity; TGCT cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg06035815 chr6:26189597 HIST1H4D 0.44 4.52 0.38 1.41e-5 Schizophrenia; TGCT cis rs4273100 0.564 rs10445411 chr17:19265797 C/T cg01534423 chr17:18965556 NA -0.78 -7.57 -0.56 7.37e-12 Schizophrenia; TGCT cis rs3820068 0.608 rs12091750 chr1:16042766 T/C cg17385448 chr1:15911702 AGMAT 0.36 4.92 0.4 2.67e-6 Systolic blood pressure; TGCT cis rs8051431 0.806 rs12927205 chr16:72025077 G/A cg06353428 chr16:71660113 MARVELD3 0.61 5.06 0.41 1.47e-6 LDL cholesterol levels; TGCT cis rs11674184 0.564 rs746579 chr2:11744694 C/T cg07314298 chr2:11723111 GREB1 -0.39 -6.59 -0.51 1.13e-9 Endometriosis; TGCT cis rs7312933 0.558 rs1796381 chr12:42842475 C/T cg19980929 chr12:42632907 YAF2 0.39 5.59 0.45 1.36e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4957048 0.891 rs11960196 chr5:568857 C/A cg09021430 chr5:549028 NA -0.42 -5.68 -0.45 9.25e-8 Ulcerative colitis; TGCT cis rs12579753 0.956 rs34146892 chr12:82188581 T/G cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs66573146 0.901 rs7668802 chr4:6986236 T/A cg01220768 chr4:7056774 TADA2B 0.41 4.86 0.4 3.49e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs10927875 0.894 rs34957618 chr1:16320499 G/C cg22431228 chr1:16359049 CLCNKA 0.23 4.44 0.37 1.94e-5 Dilated cardiomyopathy; TGCT cis rs185694 0.901 rs668301 chr13:30904082 T/G cg07600127 chr13:30881527 KATNAL1 -0.54 -4.7 -0.39 6.94e-6 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs7731657 0.537 rs973901 chr5:130362623 G/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs8177253 1.000 rs8177240 chr3:133477701 T/G cg11941060 chr3:133502564 NA -0.29 -6.11 -0.48 1.2e-8 Iron status biomarkers; TGCT cis rs67072384 1.000 rs72964185 chr11:72443177 G/A cg03713592 chr11:72463424 ARAP1 -0.92 -4.61 -0.38 9.81e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs2153535 0.580 rs1414342 chr6:8462552 A/G cg07606381 chr6:8435919 SLC35B3 0.52 4.81 0.4 4.34e-6 Motion sickness; TGCT cis rs425277 0.958 rs262687 chr1:2117155 G/A cg03732007 chr1:2071316 PRKCZ 0.25 5.3 0.43 5.15e-7 Height; TGCT cis rs12681288 0.676 rs34282191 chr8:991290 G/A cg04851639 chr8:1020857 NA -0.29 -4.8 -0.4 4.49e-6 Schizophrenia; TGCT cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg04632378 chr13:21900426 NA 0.4 4.78 0.39 4.94e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT trans rs1814175 0.817 rs7481230 chr11:49772235 G/A cg03929089 chr4:120376271 NA -0.69 -8.17 -0.59 3.03e-13 Height; TGCT cis rs6725041 0.792 rs1521643 chr2:213091417 A/G cg20637307 chr2:213403960 ERBB4 -0.52 -4.6 -0.38 1.02e-5 QT interval (ambient particulate matter interaction); TGCT cis rs9467773 0.565 rs4343916 chr6:26522675 A/T cg15659132 chr6:26577336 NA 0.73 9.04 0.63 2.64e-15 Intelligence (multi-trait analysis); TGCT cis rs4319547 0.615 rs2341439 chr12:122848096 C/G cg08088222 chr12:122070432 ORAI1 0.26 4.79 0.4 4.58e-6 Body mass index; TGCT cis rs6952808 0.609 rs10274300 chr7:1950405 C/G cg22963979 chr7:1858916 MAD1L1 -0.37 -5.58 -0.45 1.42e-7 Bipolar disorder and schizophrenia; TGCT cis rs2816062 0.813 rs2816051 chr1:18895460 A/G cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs617219 0.737 rs2166343 chr5:78484060 A/G cg23514016 chr5:78407564 BHMT 0.36 5.69 0.46 8.67e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1475911 1.000 rs2839467 chr21:43513200 A/G cg24372256 chr21:43528868 UMODL1;C21orf128 0.28 5.17 0.42 9.1e-7 IgG glycosylation; TGCT cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs4654899 0.802 rs12137203 chr1:21109088 T/A cg01072550 chr1:21505969 NA -0.49 -7.89 -0.58 1.37e-12 Superior frontal gyrus grey matter volume; TGCT cis rs769267 1.000 rs2074089 chr19:19449603 G/A cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs11718455 0.767 rs11130019 chr3:43989348 C/A cg08738300 chr3:44038990 NA 0.75 5.71 0.46 7.9e-8 Coronary artery disease; TGCT cis rs9467773 1.000 rs6926629 chr6:26499903 T/C cg26531700 chr6:26746687 NA 0.46 4.55 0.38 1.27e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.679 rs4738574 chr8:58033771 T/C cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs1474256 0.708 rs74485555 chr15:79454077 C/T cg17916960 chr15:79447300 NA 0.39 5.43 0.44 2.79e-7 Bronchopulmonary dysplasia; TGCT cis rs9611565 0.592 rs5751129 chr22:42015765 C/T cg03806693 chr22:41940476 POLR3H 0.97 9.92 0.67 2.01e-17 Vitiligo; TGCT cis rs79976124 0.800 rs12194767 chr6:66639599 A/G cg07460842 chr6:66804631 NA 0.59 5.0 0.41 1.89e-6 Type 2 diabetes; TGCT cis rs6089829 0.962 rs6062778 chr20:61663959 A/G cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs711245 1.000 rs848602 chr2:36778372 G/A cg01206211 chr2:36825736 FEZ2 0.3 4.52 0.38 1.42e-5 Height; TGCT cis rs7940866 0.874 rs10791113 chr11:130873165 A/G cg12179176 chr11:130786555 SNX19 0.56 5.4 0.44 3.34e-7 Schizophrenia; TGCT cis rs2046867 0.661 rs7637050 chr3:72910790 A/C cg25664220 chr3:72788482 NA -0.44 -5.75 -0.46 6.52e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4776059 0.550 rs8032394 chr15:52868032 G/A cg25063058 chr15:52860530 ARPP19 0.65 5.01 0.41 1.83e-6 Schizophrenia; TGCT cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.817 rs9386145 chr6:146363519 A/T cg05347473 chr6:146136440 FBXO30 0.56 5.42 0.44 2.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7428 0.527 rs4459734 chr2:85547429 G/T cg24342717 chr2:85555507 TGOLN2 -0.49 -7.81 -0.57 2.04e-12 Ear protrusion; TGCT cis rs798554 0.704 rs709282 chr7:2769921 G/A cg25467336 chr7:2757616 NA -0.24 -4.61 -0.38 9.99e-6 Height; TGCT trans rs57221529 0.545 rs55955015 chr5:575182 A/G cg25482853 chr8:67687455 SGK3 1.16 10.5 0.69 7.91e-19 Lung disease severity in cystic fibrosis; TGCT cis rs36051895 0.603 rs10974972 chr9:5130146 G/A cg02405213 chr9:5042618 JAK2 -0.76 -10.6 -0.69 4.38e-19 Pediatric autoimmune diseases; TGCT cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg18252515 chr7:66147081 NA -1.22 -7.98 -0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs4319547 0.915 rs10773208 chr12:122970156 T/C cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.32 -0.43 4.71e-7 Body mass index; TGCT cis rs72700829 0.518 rs56133109 chr1:150251915 G/A cg18798344 chr1:149336151 NA 0.56 4.5 0.37 1.52e-5 Schizophrenia; TGCT cis rs644799 1.000 rs487609 chr11:95588102 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.91 10.76 0.7 1.74e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7507204 0.723 rs12979645 chr19:3414688 A/T cg08380311 chr19:3435252 NFIC 0.98 8.25 0.6 2e-13 Height; TGCT trans rs17471911 0.708 rs11189944 chr10:100785720 G/A cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs950776 0.593 rs680244 chr15:78871288 T/C cg06917634 chr15:78832804 PSMA4 -0.65 -5.32 -0.43 4.65e-7 Sudden cardiac arrest; TGCT cis rs2204008 0.745 rs12146863 chr12:38502346 G/A cg26384229 chr12:38710491 ALG10B 0.85 7.86 0.58 1.55e-12 Bladder cancer; TGCT cis rs9581857 0.547 rs927579 chr13:28075079 A/G cg22138327 chr13:27999177 GTF3A 0.73 4.45 0.37 1.87e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg12386194 chr3:101231763 SENP7 -0.53 -5.13 -0.42 1.08e-6 Colorectal cancer; TGCT cis rs7044106 0.762 rs7024046 chr9:123419178 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.56 0.38 1.21e-5 Hip circumference adjusted for BMI; TGCT cis rs981844 0.583 rs62323859 chr4:154629690 G/A cg14289246 chr4:154710475 SFRP2 1.02 7.85 0.58 1.69e-12 Response to statins (LDL cholesterol change); TGCT cis rs4665809 0.590 rs4665319 chr2:26424583 A/C cg22920501 chr2:26401640 FAM59B -0.81 -6.42 -0.5 2.63e-9 Gut microbiome composition (summer); TGCT trans rs561341 0.883 rs1034627 chr17:30219569 C/T cg20587970 chr11:113659929 NA -0.69 -8.2 -0.59 2.6e-13 Hip circumference adjusted for BMI; TGCT cis rs36051895 0.632 rs9657576 chr9:5183028 T/G cg02405213 chr9:5042618 JAK2 -0.77 -10.84 -0.7 1.13e-19 Pediatric autoimmune diseases; TGCT cis rs4665809 1.000 rs10048648 chr2:26320315 T/C cg25036284 chr2:26402008 FAM59B -0.56 -4.88 -0.4 3.2e-6 Gut microbiome composition (summer); TGCT cis rs42648 0.869 rs6973816 chr7:89921072 C/T cg25739043 chr7:89950458 NA -0.75 -7.35 -0.55 2.31e-11 Homocysteine levels; TGCT cis rs17221829 0.537 rs7933470 chr11:89376963 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.61 -0.38 9.9e-6 Anxiety in major depressive disorder; TGCT cis rs9796 0.611 rs691672 chr15:41444438 A/C cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.86 -0.52 2.97e-10 Menopause (age at onset); TGCT cis rs2456568 0.778 rs7944194 chr11:93682413 C/G cg17595323 chr11:93583763 C11orf90 0.39 4.86 0.4 3.43e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7772486 0.790 rs6570723 chr6:146151230 A/T cg05347473 chr6:146136440 FBXO30 0.5 4.72 0.39 6.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs614226 0.938 rs7963543 chr12:120923948 C/A cg01236616 chr12:121019343 POP5 1.19 12.38 0.74 2.07e-23 Type 1 diabetes nephropathy; TGCT cis rs7681440 0.967 rs6532191 chr4:90745930 C/T cg20003494 chr4:90757398 SNCA -0.54 -5.05 -0.41 1.56e-6 Dementia with Lewy bodies; TGCT cis rs2836633 0.929 rs62217517 chr21:40033177 T/A cg12884169 chr21:40033163 ERG 0.43 4.69 0.39 7.03e-6 Coronary artery disease; TGCT cis rs9633740 1.000 rs1902660 chr10:82263683 G/C cg01528321 chr10:82214614 TSPAN14 1.03 8.42 0.6 7.78e-14 Post bronchodilator FEV1; TGCT cis rs1218582 0.772 rs877343 chr1:154910012 A/G cg03351412 chr1:154909251 PMVK 0.52 4.92 0.4 2.66e-6 Prostate cancer; TGCT cis rs889312 0.500 rs252905 chr5:56118875 C/T cg12311346 chr5:56204834 C5orf35 -0.46 -4.99 -0.41 1.97e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs4566357 0.615 rs1800517 chr2:227915832 G/A cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.92e-7 Coronary artery disease; TGCT cis rs7507204 0.906 rs1860323 chr19:3424799 G/C cg08380311 chr19:3435252 NFIC 0.94 7.99 0.58 7.76e-13 Height; TGCT cis rs138249 1.000 rs138249 chr22:50569790 C/T cg24864161 chr22:50528282 MOV10L1 0.47 4.78 0.39 4.9100000000000004e-06 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs9527 0.590 rs1926037 chr10:104878010 A/C cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs4746818 1.000 rs1506770 chr10:70964357 G/A cg11621586 chr10:70884670 VPS26A 1.23 10.93 0.7 6.87e-20 Left atrial antero-posterior diameter; TGCT cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs896854 0.608 rs6991067 chr8:95875676 A/G cg23172400 chr8:95962367 TP53INP1 -0.29 -4.55 -0.38 1.25e-5 Type 2 diabetes; TGCT cis rs981844 1.000 rs1371161 chr4:154655171 T/C cg14289246 chr4:154710475 SFRP2 1.05 8.74 0.62 1.39e-14 Response to statins (LDL cholesterol change); TGCT cis rs77633900 0.614 rs280024 chr15:77034518 A/C cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs2201728 0.967 rs17584051 chr4:100193652 C/T cg07219303 chr4:100140905 ADH6 -0.34 -5.08 -0.42 1.32e-6 Cardiac Troponin-T levels; TGCT cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg08280861 chr8:58055591 NA 0.49 5.38 0.43 3.64e-7 Developmental language disorder (linguistic errors); TGCT cis rs17331151 0.505 rs13086936 chr3:52659079 T/C cg15956490 chr3:53032818 SFMBT1 0.7 5.71 0.46 7.8e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg07636037 chr3:49044803 WDR6 0.88 9.05 0.63 2.49e-15 Menarche (age at onset); TGCT cis rs4791641 0.713 rs9908765 chr17:8214427 G/A cg18829560 chr17:7298064 PLSCR3 -0.5 -4.61 -0.38 9.85e-6 LDL cholesterol levels;Hematocrit;Hemoglobin concentration;Red blood cell count;LDL cholesterol; TGCT cis rs981844 0.890 rs56184506 chr4:154685889 G/T cg14289246 chr4:154710475 SFRP2 1.05 9.32 0.64 5.44e-16 Response to statins (LDL cholesterol change); TGCT cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg11644478 chr21:40555479 PSMG1 -0.61 -5.68 -0.45 8.9e-8 Cognitive function; TGCT cis rs939658 0.683 rs1560895 chr15:79468082 A/G cg17916960 chr15:79447300 NA -0.44 -6.95 -0.53 1.81e-10 Refractive error; TGCT cis rs1023500 0.551 rs133355 chr22:42440285 G/A cg05082376 chr22:42548792 NA -0.23 -5.42 -0.44 2.92e-7 Schizophrenia; TGCT cis rs55823223 0.646 rs74410877 chr17:73832384 C/T cg06969265 chr17:73775802 H3F3B 0.76 5.45 0.44 2.62e-7 Psoriasis; TGCT cis rs933688 1.000 rs10073935 chr5:90742188 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.09 9.69 0.66 7.22e-17 Smoking behavior; TGCT cis rs1532993 0.518 rs3913987 chr4:98606177 A/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg11301795 chr4:187892539 NA -0.33 -4.82 -0.4 4.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7255045 0.742 rs6511842 chr19:12955178 C/T cg23899408 chr19:12877188 HOOK2 -0.58 -4.78 -0.39 4.85e-6 Mean corpuscular volume; TGCT cis rs10791323 0.569 rs2282601 chr11:133712594 C/G cg15485101 chr11:133734466 NA 0.4 5.27 0.43 5.83e-7 Childhood ear infection; TGCT cis rs9486719 0.947 rs12210834 chr6:96890407 A/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs1552244 1.000 rs113771705 chr3:10075983 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs1005224 0.782 rs34882722 chr14:76153896 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.62 -5.75 -0.46 6.6e-8 Large artery stroke; TGCT cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg07061783 chr6:25882402 NA -0.59 -5.5 -0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs858239 0.601 rs4599714 chr7:23168801 C/T cg05602783 chr7:23145260 KLHL7 -0.65 -5.48 -0.44 2.32e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs66573146 1.000 rs6852613 chr4:7035637 G/A cg01220768 chr4:7056774 TADA2B 0.36 4.51 0.38 1.48e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs3087591 0.960 rs2953000 chr17:29509791 C/T cg24425628 chr17:29625626 OMG;NF1 0.46 6.82 0.52 3.5e-10 Hip circumference; TGCT cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg11494091 chr17:61959527 GH2 0.41 6.99 0.53 1.52e-10 Height; TGCT cis rs933688 1.000 rs889213 chr5:90682151 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.15 0.59 3.39e-13 Smoking behavior; TGCT cis rs7226408 0.857 rs72888997 chr18:34580216 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1475911 0.656 rs9980065 chr21:43528072 G/A cg14562523 chr21:43528734 C21orf128;UMODL1 -0.29 -5.03 -0.41 1.68e-6 IgG glycosylation; TGCT cis rs651907 0.557 rs7651406 chr3:101393296 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 11.43 0.72 4.08e-21 Colorectal cancer; TGCT trans rs208520 0.545 rs10944874 chr6:66752080 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.04 -14.69 -0.8 6.25e-29 Exhaled nitric oxide output; TGCT cis rs597539 0.615 rs583182 chr11:68678634 C/T cg04772025 chr11:68637568 NA 0.61 6.82 0.52 3.64e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2070488 0.775 rs2300669 chr3:38541318 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.73 -6.78 -0.52 4.39e-10 Electrocardiographic conduction measures; TGCT cis rs7829975 0.777 rs560544 chr8:8637429 G/A cg06636001 chr8:8085503 FLJ10661 -0.67 -5.74 -0.46 6.9e-8 Mood instability; TGCT cis rs9486715 0.867 rs9486181 chr6:96868132 G/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs10769945 0.679 rs217213 chr11:1979118 C/G cg02850416 chr11:1986266 NA -0.26 -4.57 -0.38 1.16e-5 DNA methylation (variation); TGCT cis rs6876348 0.598 rs1898550 chr5:128285661 C/T cg25555059 chr5:128301488 SLC27A6 -0.29 -4.83 -0.4 4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs79149102 0.579 rs74023935 chr15:75359184 T/C cg09165964 chr15:75287851 SCAMP5 -1.15 -6.31 -0.49 4.4e-9 Lung cancer; TGCT cis rs12950390 0.853 rs17773010 chr17:45858297 C/T cg03474202 chr17:45855739 NA -0.44 -4.51 -0.38 1.5e-5 IgG glycosylation; TGCT cis rs9677476 0.516 rs6727962 chr2:232045268 G/A cg07929768 chr2:232055508 NA 0.33 5.18 0.42 8.63e-7 Food antigen IgG levels; TGCT cis rs873946 0.564 rs2803992 chr10:134550882 T/C cg26818010 chr10:134567672 INPP5A -0.34 -4.45 -0.37 1.86e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs2727020 0.521 rs937430 chr11:49542457 A/G cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Coronary artery disease; TGCT cis rs35883536 0.647 rs10875314 chr1:101043207 G/C cg14855972 chr1:101004472 GPR88 -0.24 -4.49 -0.37 1.64e-5 Monocyte count; TGCT cis rs2120019 0.935 rs8042409 chr15:75350433 G/A cg17294928 chr15:75287854 SCAMP5 -0.81 -6.21 -0.49 7.41e-9 Blood trace element (Zn levels); TGCT cis rs7714584 1.000 rs10041072 chr5:150259642 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs7635838 0.892 rs4684775 chr3:11436413 A/G cg00170343 chr3:11313890 ATG7 0.65 6.23 0.49 6.56e-9 HDL cholesterol; TGCT cis rs12510870 0.599 rs16849651 chr4:74450308 T/C cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs854765 0.624 rs4925119 chr17:17742904 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.42 -0.5 2.66e-9 Total body bone mineral density; TGCT cis rs6752107 0.936 rs10178603 chr2:234206610 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.71 0.39 6.47e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs28595532 0.920 rs17323877 chr4:119671188 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.54 0.38 1.34e-5 Cannabis dependence symptom count; TGCT trans rs2243480 0.708 rs35825036 chr7:65986502 T/C cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg11494091 chr17:61959527 GH2 0.42 7.37 0.55 2.06e-11 Height; TGCT trans rs17011478 0.744 rs17011523 chr2:75830612 T/C cg17835207 chr20:48524531 SPATA2 -0.75 -6.91 -0.53 2.2e-10 Obesity-related traits; TGCT cis rs9527 0.590 rs12414232 chr10:104914491 A/T cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.09e-7 Arsenic metabolism; TGCT cis rs10426930 0.607 rs2613755 chr19:5059941 A/G cg09001777 chr19:5851504 FUT3 -0.22 -4.83 -0.4 3.88e-6 Monocyte percentage of white cells; TGCT cis rs17076896 0.708 rs2992950 chr13:19928251 A/C cg00777926 chr13:20807375 GJB6 0.36 4.65 0.39 8.4e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2742417 1.000 rs2245705 chr3:45749722 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.88 -0.47 3.63e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2050392 0.624 rs303449 chr10:30726845 G/A cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs6933660 0.683 rs8180642 chr6:151756612 A/G cg17179660 chr6:151773299 C6orf211;RMND1 -0.55 -4.95 -0.41 2.34e-6 Menarche (age at onset); TGCT cis rs6570726 0.791 rs407887 chr6:145843759 C/T cg23711669 chr6:146136114 FBXO30 0.88 9.55 0.65 1.54e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.624 rs12952723 chr17:17731651 T/C cg09796270 chr17:17721594 SREBF1 -0.25 -4.74 -0.39 5.78e-6 Total body bone mineral density; TGCT cis rs6831352 0.879 rs29001212 chr4:100051877 T/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs921968 0.643 rs523396 chr2:219338789 T/G cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs16867321 0.588 rs2368175 chr2:181493763 G/C cg23363182 chr2:181467187 NA -0.41 -6.15 -0.48 9.7e-9 Obesity; TGCT cis rs801193 0.569 rs2659908 chr7:66160822 G/A cg11764359 chr7:65958608 NA 0.54 4.85 0.4 3.67e-6 Aortic root size; TGCT cis rs78487399 0.808 rs6746058 chr2:43687542 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg04287289 chr16:89883240 FANCA 0.71 7.24 0.54 4.21e-11 Vitiligo; TGCT cis rs208520 1.000 rs12200490 chr6:66976084 G/A cg07460842 chr6:66804631 NA 0.81 7.17 0.54 6.08e-11 Exhaled nitric oxide output; TGCT cis rs6496044 0.547 rs1564719 chr15:86054266 C/T cg13263323 chr15:86062960 AKAP13 -0.24 -5.24 -0.43 6.59e-7 Interstitial lung disease; TGCT cis rs9796 0.835 rs3100807 chr15:41292206 G/A cg18705301 chr15:41695430 NDUFAF1 0.41 5.3 0.43 5.07e-7 Menopause (age at onset); TGCT cis rs3784262 0.565 rs4646607 chr15:58285388 A/C cg12031962 chr15:58353849 ALDH1A2 -0.39 -5.5 -0.44 2.04e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs422249 0.512 rs1535 chr11:61597972 A/G cg01500311 chr11:61656094 FADS3 -0.3 -5.25 -0.43 6.49e-7 Trans fatty acid levels; TGCT cis rs9916302 0.821 rs1966915 chr17:37425262 A/C cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs6558530 0.730 rs6991773 chr8:1723177 A/G cg09410841 chr8:1729607 CLN8 0.83 9.76 0.66 4.92e-17 Systolic blood pressure; TGCT cis rs9325144 0.560 rs2013804 chr12:38631079 C/T cg26384229 chr12:38710491 ALG10B -0.65 -6.12 -0.48 1.13e-8 Morning vs. evening chronotype; TGCT cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs6540559 0.673 rs6540560 chr1:209982073 A/G cg22029157 chr1:209979665 IRF6 -0.67 -5.63 -0.45 1.12e-7 Cleft lip with or without cleft palate; TGCT cis rs1153858 0.621 rs1706824 chr15:45579948 C/T cg14582100 chr15:45693742 SPATA5L1 0.47 5.2 0.42 8.07e-7 Homoarginine levels; TGCT cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg10117171 chr1:25599238 RHD -0.34 -5.48 -0.44 2.23e-7 Erythrocyte sedimentation rate; TGCT cis rs9611519 0.603 rs9607764 chr22:41411804 G/C cg13695892 chr22:41940480 POLR3H -0.54 -5.11 -0.42 1.19e-6 Neuroticism; TGCT cis rs79349575 0.756 rs4793605 chr17:47035869 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.48 -0.37 1.67e-5 Type 2 diabetes; TGCT cis rs4919694 1.000 rs12245779 chr10:104645944 C/A cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg23205692 chr1:25664452 TMEM50A 0.54 5.48 0.44 2.22e-7 Erythrocyte sedimentation rate; TGCT cis rs4665809 1.000 rs6546767 chr2:26328746 A/G cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs17601876 0.778 rs4774584 chr15:51562007 G/A cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs73198271 0.960 rs11778970 chr8:8609334 G/C ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.62 -0.38 9.34e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12477438 0.798 rs10198293 chr2:99602929 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.98 -13.03 -0.76 5.71e-25 Prudent dietary pattern; TGCT cis rs826838 0.967 rs11183577 chr12:38781887 A/G cg13010199 chr12:38710504 ALG10B 0.82 6.86 0.52 2.91e-10 Heart rate; TGCT cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs2180341 0.814 rs6914131 chr6:127737489 T/C cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs9527 0.590 rs2148200 chr10:104879847 C/A cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs6138458 0.961 rs227625 chr20:24911618 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs6933660 0.760 rs3806982 chr6:151774916 G/A cg14262678 chr6:151773367 RMND1;C6orf211 0.55 5.21 0.42 7.61e-7 Menarche (age at onset); TGCT cis rs11578119 0.933 rs72709774 chr1:170470628 A/C cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs12477438 0.520 rs13031919 chr2:99848932 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.69 6.2 0.49 7.74e-9 Chronic sinus infection; TGCT cis rs12549025 0.530 rs28656888 chr8:23266209 C/T cg00472375 chr8:23315376 ENTPD4 0.61 5.38 0.43 3.61e-7 Reticulocyte fraction of red cells; TGCT cis rs6921919 0.583 rs6908137 chr6:28370393 A/C cg18815343 chr6:28367644 ZSCAN12 -0.55 -5.24 -0.43 6.72e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs35306767 0.953 rs11253521 chr10:976416 G/C cg26597838 chr10:835615 NA 0.57 8.13 0.59 3.79e-13 Eosinophil percentage of granulocytes; TGCT cis rs9913156 0.517 rs12452404 chr17:4587355 C/T cg19197139 chr17:4613644 ARRB2 -0.6 -5.74 -0.46 6.88e-8 Lymphocyte counts; TGCT cis rs12950390 0.853 rs11079791 chr17:45859099 C/T cg24803719 chr17:45855879 NA -0.49 -5.03 -0.41 1.64e-6 IgG glycosylation; TGCT cis rs5750830 0.649 rs7949 chr22:39827553 G/A cg01416388 chr22:39784598 NA -0.7 -6.92 -0.53 2.11e-10 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.0 8.22 0.59 2.32e-13 Platelet count; TGCT cis rs7772486 0.846 rs7755440 chr6:146375906 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs2258884 chr20:25279539 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs6582630 0.638 rs12231073 chr12:38526901 T/G cg26384229 chr12:38710491 ALG10B -0.55 -4.89 -0.4 3.05e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2235642 0.859 rs9927529 chr16:1619488 C/T cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.07 -0.41 1.4e-6 Coronary artery disease; TGCT cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg03609598 chr5:56110824 MAP3K1 -0.6 -4.86 -0.4 3.55e-6 Initial pursuit acceleration; TGCT cis rs28595532 0.702 rs116320061 chr4:119384600 C/T cg21605333 chr4:119757512 SEC24D 0.81 5.35 0.43 4.16e-7 Cannabis dependence symptom count; TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg20111269 chr12:107972364 BTBD11 -0.88 -7.09 -0.54 8.76e-11 Follicular lymphoma; TGCT cis rs425277 0.606 rs262669 chr1:2082489 A/G cg03732007 chr1:2071316 PRKCZ -0.28 -6.66 -0.51 8.15e-10 Height; TGCT cis rs7940866 0.804 rs6590540 chr11:130805444 T/C cg12179176 chr11:130786555 SNX19 0.59 5.81 0.46 4.88e-8 Schizophrenia; TGCT cis rs11252926 0.502 rs7072510 chr10:455596 C/T cg20256804 chr10:444983 DIP2C -0.21 -4.52 -0.38 1.41e-5 Psychosis in Alzheimer's disease; TGCT cis rs7568458 0.846 rs2028900 chr2:85767735 A/G cg02493740 chr2:85810744 VAMP5 0.27 5.0 0.41 1.87e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2404618 0.534 rs2214861 chr8:1490604 A/G cg13402656 chr8:1511478 DLGAP2 -0.35 -6.33 -0.49 4.12e-9 Lung cancer; TGCT cis rs5757676 0.858 rs6001585 chr22:39812986 G/T cg24399712 chr22:39784796 NA -0.98 -8.59 -0.61 3.16e-14 IgG glycosylation; TGCT cis rs10791097 0.739 rs4936120 chr11:130723452 G/A cg14779329 chr11:130786720 SNX19 0.27 4.59 0.38 1.06e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1218582 0.772 rs10796935 chr1:154891363 G/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs7666738 0.893 rs11729640 chr4:99052699 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9926296 0.533 rs12102297 chr16:89812762 C/A cg03388025 chr16:89894329 SPIRE2 0.48 8.07 0.59 5.2e-13 Vitiligo; TGCT cis rs7829975 0.577 rs79495969 chr8:8545250 G/A cg08975724 chr8:8085496 FLJ10661 -0.51 -4.44 -0.37 1.96e-5 Mood instability; TGCT cis rs986417 1.000 rs10130267 chr14:60944527 A/G cg27398547 chr14:60952738 C14orf39 1.42 8.68 0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs9549367 0.756 rs3861723 chr13:113910926 A/G cg00898013 chr13:113819073 PROZ -0.38 -4.99 -0.41 2.01e-6 Platelet distribution width; TGCT cis rs28595532 0.841 rs112953035 chr4:119752450 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs17052344 0.543 rs2342183 chr17:21738349 G/T cg18423549 chr17:21743878 NA -0.61 -5.99 -0.47 2.14e-8 Cutaneous psoriasis; TGCT cis rs1150668 0.764 rs9368565 chr6:28345210 C/T cg13525197 chr6:28411240 ZSCAN23 0.5 4.89 0.4 3.1e-6 Pubertal anthropometrics; TGCT cis rs10789491 1.000 rs1890473 chr1:47149794 C/T cg15501359 chr1:47185051 KIAA0494 0.78 7.43 0.55 1.55e-11 Response to hepatitis C treatment; TGCT cis rs1801251 1.000 rs283469 chr2:233656997 G/T cg25237894 chr2:233734115 C2orf82 0.31 5.41 0.44 3.17e-7 Coronary artery disease; TGCT cis rs9913156 0.793 rs9916135 chr17:4568115 A/C cg19197139 chr17:4613644 ARRB2 -0.87 -8.05 -0.59 5.79e-13 Lymphocyte counts; TGCT cis rs2932538 0.922 rs34531155 chr1:113141550 C/T cg22162597 chr1:113214053 CAPZA1 0.28 5.83 0.46 4.4e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2224391 0.628 rs9392666 chr6:5249888 C/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs1729951 0.575 rs10935214 chr3:136693485 G/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs9604529 0.557 rs74841821 chr13:114742213 G/A cg13259177 chr13:114761607 RASA3 -0.27 -4.54 -0.38 1.32e-5 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs1865760 0.566 rs2032443 chr6:26046802 A/G cg16482183 chr6:26056742 HIST1H1C 0.57 4.97 0.41 2.21e-6 Height; TGCT cis rs881375 0.678 rs10760129 chr9:123700183 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.93 0.4 2.56e-6 Rheumatoid arthritis; TGCT cis rs1784581 0.674 rs1789990 chr6:162406957 G/T cg17173639 chr6:162384350 PARK2 -0.39 -6.79 -0.52 4.1e-10 Itch intensity from mosquito bite; TGCT cis rs11112613 0.713 rs17037317 chr12:105952058 T/C cg03607813 chr12:105948248 NA 0.47 5.72 0.46 7.49e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg16414030 chr3:133502952 NA -0.49 -6.92 -0.53 2.13e-10 Iron status biomarkers; TGCT trans rs629535 0.814 rs604254 chr8:70059164 A/G cg21567404 chr3:27674614 NA 0.56 8.83 0.62 8.17e-15 Dupuytren's disease; TGCT cis rs637571 0.544 rs617791 chr11:65702523 C/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.56 5.33 0.43 4.42e-7 Eosinophil percentage of white cells; TGCT cis rs929354 1.000 rs1182389 chr7:157038803 C/T cg05182265 chr7:156933206 UBE3C -0.3 -6.43 -0.5 2.5e-9 Body mass index; TGCT cis rs10986311 0.889 rs3780204 chr9:127092887 C/G cg14243010 chr9:127117328 LOC100129034;PSMB7 0.2 4.58 0.38 1.13e-5 Vitiligo; TGCT cis rs71435601 0.600 rs573314 chr2:21385161 C/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs2120019 0.935 rs34835684 chr15:75331805 T/G cg09165964 chr15:75287851 SCAMP5 -1.14 -10.22 -0.68 3.76e-18 Blood trace element (Zn levels); TGCT cis rs826838 1.000 rs11183469 chr12:38752311 G/A cg26384229 chr12:38710491 ALG10B 1.08 10.86 0.7 1.01e-19 Heart rate; TGCT cis rs6964587 1.000 rs56072181 chr7:91690457 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs138249 0.934 rs138234 chr22:50560372 C/T cg24864161 chr22:50528282 MOV10L1 0.47 5.02 0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs11098499 0.863 rs13149407 chr4:120437825 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs2535633 0.594 rs2581789 chr3:53096230 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.51 4.92 0.4 2.73e-6 Body mass index; TGCT cis rs9311474 0.632 rs6445528 chr3:52572447 C/T cg07507251 chr3:52567010 NT5DC2 -0.46 -6.41 -0.5 2.74e-9 Electroencephalogram traits; TGCT cis rs9682041 0.932 rs7631221 chr3:170069893 A/G cg07589077 chr3:170072950 NA 0.37 5.29 0.43 5.42e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs3806843 0.900 rs2531341 chr5:140130894 C/T cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2178146 0.535 rs4843945 chr16:86444032 A/C cg11165158 chr16:86613094 FOXL1 -0.35 -4.47 -0.37 1.73e-5 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT cis rs7267979 0.816 rs390123 chr20:25480105 C/G cg16686733 chr20:25566563 NINL 0.52 5.05 0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6860806 0.507 rs272868 chr5:131680751 C/G cg24060327 chr5:131705240 SLC22A5 -0.75 -8.27 -0.6 1.8e-13 Breast cancer; TGCT cis rs4688759 0.719 rs73079018 chr3:49875327 T/C cg07636037 chr3:49044803 WDR6 -0.99 -4.74 -0.39 5.85e-6 Blood protein levels; TGCT cis rs6570726 0.875 rs1883407 chr6:145823432 T/C cg23711669 chr6:146136114 FBXO30 0.69 6.22 0.49 6.89e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs478304 0.593 rs4645927 chr11:65482827 C/T cg27068330 chr11:65405492 SIPA1 -0.98 -9.26 -0.64 7.7e-16 Acne (severe); TGCT cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg01802117 chr1:53393560 SCP2 -0.44 -5.45 -0.44 2.6e-7 Monocyte count; TGCT cis rs7666738 0.791 rs1559860 chr4:99024422 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs8072100 0.713 rs2292346 chr17:45455473 G/A cg08085267 chr17:45401833 C17orf57 -0.5 -5.47 -0.44 2.38e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs933688 1.000 rs6452951 chr5:90653868 T/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 10.13 0.67 6.16e-18 Smoking behavior; TGCT cis rs13082711 0.522 rs3103745 chr3:27342927 T/C cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2617583 0.509 rs748209 chr5:1457554 A/C cg13982541 chr5:1466431 LPCAT1 0.2 4.77 0.39 5.07e-6 Breast cancer; TGCT cis rs2224391 0.628 rs2753243 chr6:5256261 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.02 -6.25 -0.49 6.07e-9 Height; TGCT cis rs922182 0.904 rs9972469 chr15:64283793 C/A cg02919090 chr15:64263738 DAPK2 0.31 5.83 0.46 4.58e-8 Blood protein levels; TGCT cis rs2239815 0.515 rs5762829 chr22:29228130 A/G cg02153584 chr22:29168773 CCDC117 0.78 5.37 0.43 3.81e-7 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs950880 0.560 rs59247511 chr2:102954190 T/C cg09003973 chr2:102972529 NA -0.53 -4.59 -0.38 1.06e-5 Serum protein levels (sST2); TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs7662114 chr4:99019985 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.825 rs12153021 chr5:93073913 A/G cg25358565 chr5:93447407 FAM172A 0.89 7.39 0.55 1.89e-11 Diabetic retinopathy; TGCT cis rs2228479 0.850 rs11644526 chr16:89898660 C/T cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs1008375 0.646 rs13103430 chr4:17567355 A/C cg18681998 chr4:17616180 MED28 -0.65 -5.55 -0.45 1.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4919694 1.000 rs11191439 chr10:104638723 C/T cg24592962 chr10:104629151 AS3MT 0.83 4.55 0.38 1.27e-5 Arsenic metabolism; TGCT cis rs79976124 0.837 rs12194087 chr6:66644399 T/A cg07460842 chr6:66804631 NA 0.57 5.22 0.42 7.44e-7 Type 2 diabetes; TGCT cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.09 -0.42 1.29e-6 Electroencephalogram traits; TGCT cis rs7945705 0.791 rs12421789 chr11:8813956 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -4.63 -0.38 9.11e-6 Hemoglobin concentration; TGCT cis rs9549260 0.564 rs8000965 chr13:41279488 C/T cg21288729 chr13:41239152 FOXO1 0.94 8.95 0.63 4.28e-15 Red blood cell count; TGCT cis rs709400 0.628 rs4906321 chr14:103878882 C/T cg12935359 chr14:103987150 CKB -0.29 -4.57 -0.38 1.15e-5 Body mass index; TGCT cis rs7772486 0.651 rs1292338 chr6:145967471 A/C cg13319975 chr6:146136371 FBXO30 0.5 4.6 0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs78487399 0.808 rs74365854 chr2:43661482 T/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.45 -5.35 -0.43 4.03e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1322512 1.000 rs7765586 chr6:152949109 C/T cg03415253 chr6:152958462 SYNE1 0.57 4.99 0.41 2e-6 Tonometry; TGCT cis rs2932538 0.883 rs6696991 chr1:113095661 C/T cg22162597 chr1:113214053 CAPZA1 0.25 5.5 0.44 2.06e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs644799 1.000 rs563653 chr11:95561488 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs79349575 0.783 rs4793998 chr17:47019899 C/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT trans rs10435719 0.902 rs11250179 chr8:11800332 C/T cg15556689 chr8:8085844 FLJ10661 0.78 7.35 0.55 2.32e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg02353165 chr6:42928485 GNMT 0.99 10.14 0.67 5.89e-18 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs35771425 0.626 rs11119744 chr1:211644575 C/T cg10512769 chr1:211675356 NA -0.28 -4.96 -0.41 2.29e-6 Educational attainment (years of education); TGCT cis rs9916302 0.847 rs7218670 chr17:37500424 G/A cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs2274273 0.682 rs10145268 chr14:55504514 T/C cg01923255 chr14:55878535 KIAA0831 0.56 4.94 0.41 2.51e-6 Protein biomarker; TGCT cis rs6882046 0.513 rs616391 chr5:88038845 C/T cg24804195 chr5:87968844 LOC645323 -0.57 -5.68 -0.45 9.26e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs988712 0.705 rs10501087 chr11:27670108 C/T cg10635145 chr11:27742435 BDNF 0.38 5.25 0.43 6.38e-7 Obesity; TGCT trans rs11785693 0.909 rs62489556 chr8:4968149 G/A cg21607066 chr6:79787807 PHIP 0.91 6.8 0.52 3.93e-10 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs13323323 0.696 rs66922431 chr3:44474551 C/T cg04389838 chr3:44770851 ZNF501 -0.43 -4.74 -0.39 5.76e-6 IgG glycosylation; TGCT cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg16049864 chr8:95962084 TP53INP1 -0.77 -11.21 -0.71 1.44e-20 Type 2 diabetes; TGCT cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs2576037 0.523 rs590923 chr18:44404259 G/C cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs11190604 1.000 rs12358187 chr10:102284449 C/G cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2204008 0.683 rs11522927 chr12:38137537 C/T cg26384229 chr12:38710491 ALG10B 0.89 7.92 0.58 1.14e-12 Bladder cancer; TGCT cis rs12900413 0.603 rs12907030 chr15:90301439 C/T cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7681440 0.904 rs28777703 chr4:90769924 A/G cg26578617 chr4:90757533 SNCA 0.46 4.74 0.39 5.65e-6 Dementia with Lewy bodies; TGCT cis rs35146811 0.700 rs2950520 chr7:99827148 T/C cg13334819 chr7:99746414 C7orf59 0.74 6.42 0.5 2.64e-9 Coronary artery disease; TGCT trans rs2727020 0.521 rs11040408 chr11:49534880 A/T cg11707556 chr5:10655725 ANKRD33B 0.39 8.0 0.58 7.44e-13 Coronary artery disease; TGCT cis rs17001868 0.568 rs9607701 chr22:40739116 A/G cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs9926296 0.712 rs258332 chr16:89727683 G/A cg01097406 chr16:89675127 NA 0.36 6.25 0.49 6.05e-9 Vitiligo; TGCT cis rs4665809 1.000 rs1030730 chr2:26284143 T/C cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs4242434 0.672 rs4615566 chr8:22520682 T/C cg21658235 chr8:22456391 C8orf58 -0.42 -4.46 -0.37 1.84e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs28595532 0.702 rs56217716 chr4:119338490 T/G cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs597539 0.652 rs646586 chr11:68681653 C/T cg21862992 chr11:68658383 NA -0.36 -4.75 -0.39 5.42e-6 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9611565 0.729 rs137831 chr22:41903813 A/C cg06634786 chr22:41940651 POLR3H -0.79 -7.51 -0.56 1.01e-11 Vitiligo; TGCT cis rs2050392 0.767 rs2183175 chr10:30699336 A/G cg13289132 chr10:30722225 MAP3K8 0.44 5.42 0.44 2.96e-7 Inflammatory bowel disease; TGCT cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg13342137 chr4:2252803 MXD4 0.17 4.65 0.39 8.28e-6 Obesity-related traits; TGCT cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg11890956 chr21:40555474 PSMG1 1.1 12.36 0.74 2.27e-23 Cognitive function; TGCT cis rs2749592 0.588 rs2505192 chr10:38395023 G/A cg25427524 chr10:38739819 LOC399744 -0.4 -6.97 -0.53 1.62e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs634534 0.561 rs14157 chr11:65769780 T/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.65 6.42 0.5 2.59e-9 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs6840360 0.615 rs28659854 chr4:152607442 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.15 -0.48 9.82e-9 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs7027203 0.790 rs10123836 chr9:96584109 G/T cg14598338 chr9:96623480 NA -0.61 -9.56 -0.65 1.43e-16 DNA methylation (variation); TGCT cis rs7027203 0.557 rs9299411 chr9:96523104 C/A cg14598338 chr9:96623480 NA -0.49 -7.04 -0.53 1.18e-10 DNA methylation (variation); TGCT cis rs56176327 0.583 rs7613603 chr3:49812866 C/T cg05785598 chr3:49045655 WDR6 -0.42 -5.24 -0.43 6.67e-7 Intelligence (multi-trait analysis); TGCT cis rs11252926 0.537 rs4554800 chr10:458477 G/T cg13477178 chr10:375248 DIP2C 0.24 4.73 0.39 5.9e-6 Psychosis in Alzheimer's disease; TGCT cis rs6840360 0.593 rs1429558 chr4:152685406 A/T cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.63e-8 Intelligence (multi-trait analysis); TGCT trans rs10506458 0.915 rs12426017 chr12:63396272 T/G cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs7267979 0.932 rs1541061 chr20:25521057 G/A cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11105298 0.891 rs11105318 chr12:89926658 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.73 -5.59 -0.45 1.39e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT trans rs7615952 0.932 rs3811679 chr3:125648283 A/G cg07211511 chr3:129823064 LOC729375 -0.47 -7.55 -0.56 8.34e-12 Blood pressure (smoking interaction); TGCT cis rs6964587 1.000 rs416 chr7:91580571 A/G cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs17270561 0.723 rs12192635 chr6:25880907 A/T cg17042849 chr6:26104293 HIST1H4C -0.8 -5.87 -0.47 3.66e-8 Iron status biomarkers; TGCT cis rs7833790 0.724 rs6473309 chr8:82707880 A/G cg17211192 chr8:82754475 SNX16 -0.95 -8.78 -0.62 1.09e-14 Diastolic blood pressure; TGCT cis rs28595532 1.000 rs115004746 chr4:119642137 C/T cg11846333 chr4:119757529 SEC24D 0.92 4.6 0.38 1.02e-5 Cannabis dependence symptom count; TGCT cis rs11235843 0.602 rs7106773 chr11:73383174 C/G cg18195628 chr11:73498948 MRPL48 -0.64 -4.52 -0.38 1.42e-5 Hand grip strength; TGCT cis rs6500602 0.964 rs13335685 chr16:4469284 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.17 0.42 9.12e-7 Schizophrenia; TGCT cis rs950169 1.000 rs1911155 chr15:84787635 A/G cg17173187 chr15:85201210 NMB 0.51 5.6 0.45 1.3e-7 Schizophrenia; TGCT cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs4144743 0.941 rs10438782 chr17:45323892 G/A cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs72634258 0.554 rs12092614 chr1:7865710 C/T cg26816564 chr1:7831052 VAMP3 0.87 6.44 0.5 2.34e-9 Inflammatory bowel disease; TGCT cis rs6089584 0.546 rs6061978 chr20:60615604 C/T cg13770153 chr20:60521292 NA -0.4 -4.95 -0.41 2.38e-6 Body mass index; TGCT cis rs9467711 0.516 rs1177441 chr6:25859413 A/G cg03264133 chr6:25882463 NA -0.67 -4.47 -0.37 1.76e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs12478296 1.000 rs55777943 chr2:243040686 T/C cg06360820 chr2:242988706 NA -0.81 -5.39 -0.44 3.36e-7 Obesity-related traits; TGCT cis rs896854 0.846 rs13254283 chr8:95914103 G/T cg09323728 chr8:95962352 TP53INP1 -0.49 -6.33 -0.49 4.07e-9 Type 2 diabetes; TGCT cis rs6089829 0.855 rs6090205 chr20:61665269 A/G cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs977747 0.872 rs4926725 chr1:47679366 A/T cg03885399 chr1:47691550 TAL1 -0.4 -5.15 -0.42 1e-6 Body mass index; TGCT cis rs933688 1.000 rs6866191 chr5:90746852 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 8.8 0.62 9.68e-15 Smoking behavior; TGCT cis rs10949834 0.838 rs1091811 chr7:73491212 A/G cg07137043 chr7:73588983 EIF4H 0.63 4.61 0.38 1e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs12188164 1.000 rs55842567 chr5:437586 G/A cg21144161 chr5:423903 AHRR 0.26 4.94 0.41 2.49e-6 Cystic fibrosis severity; TGCT cis rs1018836 0.632 rs2879361 chr8:91481909 C/T cg16814680 chr8:91681699 NA 0.79 8.31 0.6 1.43e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT trans rs916888 0.779 rs199528 chr17:44843136 C/T cg01341218 chr17:43662625 NA 1.09 9.23 0.64 9.27e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs78487399 0.908 rs72868625 chr2:43831186 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs892961 0.932 rs67719929 chr17:75412605 G/A cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs832540 1.000 rs832540 chr5:56199202 G/A cg24531977 chr5:56204891 C5orf35 -0.54 -5.57 -0.45 1.53e-7 Coronary artery disease; TGCT cis rs6500602 0.727 rs1477123 chr16:4560627 T/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.15 0.48 9.72e-9 Schizophrenia; TGCT cis rs12497850 0.865 rs13072911 chr3:48962128 T/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs6582630 0.502 rs7312212 chr12:38274760 T/G cg26384229 chr12:38710491 ALG10B 0.84 7.29 0.55 3.2e-11 Drug-induced liver injury (flucloxacillin); TGCT trans rs916888 0.821 rs199512 chr17:44857352 T/C cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9638182 0.725 rs35695283 chr7:72893403 A/G cg14087351 chr7:73037990 MLXIPL -0.61 -4.81 -0.4 4.34e-6 Triglycerides; TGCT cis rs9457247 1.000 rs400063 chr6:167386592 C/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs968451 1.000 rs11703434 chr22:39698915 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.87 7.8 0.57 2.23e-12 Primary biliary cholangitis; TGCT cis rs3862260 0.509 rs12076924 chr1:120165826 C/T cg16322792 chr1:120165303 ZNF697 0.36 8.35 0.6 1.15e-13 Systemic lupus erythematosus; TGCT cis rs854765 0.693 rs35451946 chr17:17764061 C/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.78 -0.39 4.77e-6 Total body bone mineral density; TGCT cis rs9486715 0.867 rs9384585 chr6:96875664 C/T cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs6545883 0.894 rs6760075 chr2:61612881 C/A cg15711740 chr2:61764176 XPO1 0.55 4.94 0.41 2.52e-6 Tuberculosis; TGCT cis rs3008870 0.959 rs2985816 chr1:67387750 G/T cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs7647973 1.000 rs3870341 chr3:49584745 A/G cg07636037 chr3:49044803 WDR6 0.61 5.0 0.41 1.95e-6 Menarche (age at onset); TGCT cis rs7772486 0.558 rs2142978 chr6:146012061 T/C cg05347473 chr6:146136440 FBXO30 -0.65 -6.11 -0.48 1.17e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs3858526 0.796 rs9645652 chr11:5944264 C/T cg13902645 chr11:5959945 NA -0.44 -4.61 -0.38 9.67e-6 DNA methylation (variation); TGCT cis rs4366490 0.687 rs1939751 chr11:62910269 C/T cg21002970 chr11:62369079 MTA2 0.71 5.03 0.41 1.66e-6 Conotruncal heart defects; TGCT cis rs2932538 0.846 rs7546203 chr1:113154529 C/A cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1158570 0.564 rs2791343 chr8:131316030 C/T cg16277922 chr8:131349729 ASAP1 -0.47 -6.61 -0.51 1.04e-9 Platelet count; TGCT cis rs9443645 0.901 rs2050660 chr6:79734726 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.548 rs6500439 chr16:89808275 A/C cg27121462 chr16:89883253 FANCA 0.83 9.13 0.63 1.57e-15 Vitiligo; TGCT cis rs7829975 1.000 rs7829975 chr8:8548117 T/A cg15556689 chr8:8085844 FLJ10661 -0.73 -6.5 -0.5 1.73e-9 Mood instability; TGCT cis rs12220238 1.000 rs10824114 chr10:75970503 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7098414 0.511 rs4934134 chr10:82160582 C/T cg00277334 chr10:82204260 NA -0.38 -4.98 -0.41 2.08e-6 Post bronchodilator FEV1; TGCT cis rs10504229 1.000 rs73591706 chr8:58195633 C/T cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs6582630 0.615 rs11182380 chr12:38511735 G/T cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.830 rs10034330 chr4:99064849 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.37e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10028773 0.600 rs4001390 chr4:120265783 G/C cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.08e-7 Educational attainment; TGCT cis rs80282103 0.867 rs7075830 chr10:1091650 G/C cg08668510 chr10:1095578 IDI1 1.17 4.75 0.39 5.44e-6 Glomerular filtration rate (creatinine); TGCT cis rs7637230 0.541 rs2449493 chr3:101454514 A/T cg12932813 chr3:101280753 RG9MTD1 1.26 7.51 0.56 9.95e-12 Psoriasis vulgaris;Psoriasis; TGCT cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg06634786 chr22:41940651 POLR3H 0.89 8.4 0.6 8.56e-14 Vitiligo; TGCT cis rs733175 0.857 rs3796838 chr4:10011030 C/T cg00071950 chr4:10020882 SLC2A9 0.54 4.54 0.38 1.3e-5 Psychosis and Alzheimer's disease; TGCT cis rs9911578 0.967 rs7222789 chr17:56819853 C/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs9952991 0.622 rs547268 chr18:12823056 G/T cg23544223 chr18:12777786 NA 0.53 4.68 0.39 7.25e-6 Inflammatory skin disease; TGCT cis rs4253772 0.550 rs6008613 chr22:46707924 G/T cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT trans rs531864 0.570 rs486153 chr2:169682966 T/C cg16341836 chr10:90641389 STAMBPL1 -0.29 -7.15 -0.54 6.5e-11 Mitochondrial DNA levels; TGCT cis rs4285028 0.747 rs1463736 chr3:121400725 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg03303774 chr4:1407052 NA 0.29 4.77 0.39 4.98e-6 Obesity-related traits; TGCT cis rs4975616 0.869 rs421284 chr5:1325590 T/C cg06550200 chr5:1325588 CLPTM1L -0.3 -4.6 -0.38 1.04e-5 Lung cancer; TGCT cis rs12422267 0.536 rs12423631 chr12:132606886 C/T cg09764611 chr12:132620959 NA -0.38 -5.52 -0.44 1.9e-7 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs68170813 0.559 rs1548523 chr7:106944408 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs911555 0.723 rs11160751 chr14:103925740 T/C cg12935359 chr14:103987150 CKB -0.32 -4.47 -0.37 1.73e-5 Intelligence (multi-trait analysis); TGCT cis rs5750830 0.649 rs5750822 chr22:39826788 C/T cg05872129 chr22:39784769 NA -0.96 -10.82 -0.7 1.29e-19 Intelligence (multi-trait analysis); TGCT cis rs7617480 0.648 rs6806356 chr3:48727636 G/A cg07636037 chr3:49044803 WDR6 0.77 6.32 0.49 4.38e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs6933660 0.800 rs9383893 chr6:151757327 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.7 7.16 0.54 6.11e-11 Menarche (age at onset); TGCT cis rs372883 0.648 rs2832296 chr21:30741454 C/T cg24692254 chr21:30365293 RNF160 -0.49 -4.49 -0.37 1.58e-5 Pancreatic cancer; TGCT cis rs433598 0.765 rs163265 chr16:20661809 A/G cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -5.07 -0.41 1.42e-6 Schizophrenia; TGCT cis rs7255045 0.752 rs2418568 chr19:12987881 A/G cg06537894 chr19:12978706 MAST1 -0.49 -4.47 -0.37 1.73e-5 Mean corpuscular volume; TGCT cis rs9549367 0.713 rs3024756 chr13:113822950 G/C cg18105134 chr13:113819100 PROZ -0.48 -8.35 -0.6 1.13e-13 Platelet distribution width; TGCT cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg08280861 chr8:58055591 NA 0.39 4.76 0.39 5.35e-6 Developmental language disorder (linguistic errors); TGCT cis rs9341808 0.754 rs3812126 chr6:80952701 A/G cg08355045 chr6:80787529 NA -0.29 -5.03 -0.41 1.71e-6 Sitting height ratio; TGCT cis rs3617 0.559 rs11915546 chr3:52866845 A/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1023500 0.551 rs133371 chr22:42465574 G/A cg05082376 chr22:42548792 NA -0.22 -5.41 -0.44 3.18e-7 Schizophrenia; TGCT cis rs9325144 0.505 rs901635 chr12:38646572 A/C cg26384229 chr12:38710491 ALG10B -0.72 -7.04 -0.53 1.19e-10 Morning vs. evening chronotype; TGCT cis rs877282 0.853 rs11593836 chr10:756715 G/A cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs13242816 1.000 rs35538349 chr7:116117896 C/T cg16553024 chr7:116138462 CAV2 -0.45 -4.81 -0.4 4.32e-6 P wave duration; TGCT cis rs7829975 0.501 rs74345345 chr8:8578435 C/G cg15556689 chr8:8085844 FLJ10661 -0.53 -4.49 -0.37 1.62e-5 Mood instability; TGCT cis rs7904368 0.901 rs7923189 chr10:16850214 C/T cg23933602 chr10:16859644 RSU1 0.64 4.88 0.4 3.24e-6 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs4319547 0.656 rs7975747 chr12:122816995 C/T cg05707623 chr12:122985044 ZCCHC8 -0.59 -4.5 -0.37 1.57e-5 Body mass index; TGCT cis rs9389248 0.708 rs7750574 chr6:135350932 G/C cg24558204 chr6:135376177 HBS1L 0.48 4.97 0.41 2.22e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs9325144 0.624 rs10506126 chr12:39123244 G/A cg13010199 chr12:38710504 ALG10B -0.52 -4.68 -0.39 7.48e-6 Morning vs. evening chronotype; TGCT cis rs2066819 1.000 rs116849218 chr12:56683975 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs17376456 0.825 rs10038828 chr5:93124056 C/T cg21475434 chr5:93447410 FAM172A 0.63 4.77 0.39 5.03e-6 Diabetic retinopathy; TGCT trans rs17471911 0.529 rs79483496 chr10:100782911 C/T cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs4455778 0.659 rs2364009 chr7:49030673 T/G cg26309511 chr7:48887640 NA 0.44 5.22 0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs7973719 0.833 rs7962563 chr12:7353514 G/A cg07052231 chr12:7363540 PEX5 0.36 5.6 0.45 1.31e-7 IgG glycosylation; TGCT cis rs11190604 1.000 rs9420785 chr10:102240451 C/G cg16342193 chr10:102329863 NA -0.39 -5.17 -0.42 9.29e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9357506 0.967 rs9395176 chr6:46318000 T/C cg21115430 chr6:46460003 NA -0.23 -4.52 -0.38 1.4e-5 Body mass index; TGCT cis rs3784262 0.669 rs2197092 chr15:58247781 C/T cg12031962 chr15:58353849 ALDH1A2 0.44 6.32 0.49 4.39e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1008375 0.646 rs13145480 chr4:17565143 T/C cg10189774 chr4:17578691 LAP3 -0.58 -4.94 -0.41 2.52e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs826838 1.000 rs11610522 chr12:38687575 C/T cg26384229 chr12:38710491 ALG10B 1.12 11.32 0.71 7.88e-21 Heart rate; TGCT cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg04546413 chr19:29218101 NA 0.84 6.82 0.52 3.52e-10 Methadone dose in opioid dependence; TGCT cis rs7819412 0.608 rs28417109 chr8:10975081 T/A cg03192020 chr8:11204681 TDH -0.51 -4.6 -0.38 1.02e-5 Triglycerides; TGCT cis rs9534288 0.797 rs4942467 chr13:46599817 A/C cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs4819052 0.851 rs2838865 chr21:46712299 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.06 6.75 0.52 5.03e-10 Gut microbiome composition (summer); TGCT cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg02725872 chr8:58115012 NA -0.39 -4.83 -0.4 3.9e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.825 rs28817407 chr1:53226116 G/A cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.41 2.55e-6 Monocyte count; TGCT cis rs1801251 0.778 rs709934 chr2:233733352 A/G cg08000102 chr2:233561755 GIGYF2 -0.44 -4.53 -0.38 1.39e-5 Coronary artery disease; TGCT cis rs4319547 0.656 rs7294559 chr12:122837564 C/A cg05707623 chr12:122985044 ZCCHC8 -0.62 -4.89 -0.4 3.06e-6 Body mass index; TGCT cis rs7772486 0.692 rs1577916 chr6:146069789 G/A cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 0.581 rs2108838 chr16:89904426 A/G cg03388025 chr16:89894329 SPIRE2 0.35 5.21 0.42 7.63e-7 Vitiligo; TGCT cis rs3785574 0.962 rs13030 chr17:61908556 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.45 0.44 2.66e-7 Height; TGCT cis rs4566357 0.615 rs10190621 chr2:227914484 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -5.09 -0.42 1.28e-6 Coronary artery disease; TGCT cis rs1568889 0.838 rs10458896 chr11:28057957 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.35 0.71 6.62e-21 Bipolar disorder; TGCT cis rs10779751 1.000 rs7544489 chr1:11299511 A/G cg08854313 chr1:11322531 MTOR -0.94 -10.5 -0.69 7.65e-19 Body mass index; TGCT cis rs7746199 0.668 rs7749305 chr6:27446566 T/C cg10876282 chr6:28092338 ZSCAN16 0.88 4.52 0.38 1.44e-5 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs9990333 0.562 rs75681503 chr3:195822285 G/A cg14488913 chr3:195402182 SDHAP2 -0.36 -4.6 -0.38 1.03e-5 Iron status biomarkers (transferrin levels);Iron status biomarkers (transferrin saturation); TGCT cis rs1865760 1.000 rs1865760 chr6:25916979 C/T cg16482183 chr6:26056742 HIST1H1C 0.52 4.6 0.38 1.04e-5 Height; TGCT cis rs12681287 0.547 rs9942823 chr8:87509177 A/G cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs3806843 0.735 rs801168 chr5:140080298 A/G cg19875535 chr5:140030758 IK -0.36 -6.14 -0.48 1.04e-8 Depressive symptoms (multi-trait analysis); TGCT trans rs62103177 0.733 rs62103232 chr18:77635553 G/A cg05926928 chr17:57297772 GDPD1 1.26 11.72 0.72 8.33e-22 Opioid sensitivity; TGCT cis rs854765 0.547 rs4459604 chr17:17888549 A/G cg09796270 chr17:17721594 SREBF1 0.26 5.09 0.42 1.3e-6 Total body bone mineral density; TGCT cis rs7614311 0.731 rs3774727 chr3:63977875 A/G cg22134162 chr3:63841271 THOC7 -0.43 -5.68 -0.45 9.12e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs12142240 0.698 rs1057533 chr1:46815836 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7226408 0.843 rs10153358 chr18:34334556 C/T cg06757138 chr18:34340585 FHOD3 0.3 5.46 0.44 2.52e-7 Obesity-related traits; TGCT cis rs2576037 0.583 rs10070 chr18:44388899 G/A cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs4499344 0.730 rs2868150 chr19:33098875 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs7752195 0.643 rs78252389 chr6:25257530 C/T cg16898833 chr6:26189333 HIST1H4D 1.17 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs861020 1.000 rs630984 chr1:209982293 C/T cg05527609 chr1:210001259 C1orf107 0.94 7.82 0.57 1.95e-12 Orofacial clefts; TGCT cis rs7439150 1.000 rs72681208 chr4:155478389 A/T cg22130008 chr4:155548532 NA -0.44 -5.59 -0.45 1.36e-7 Fibrinogen levels; TGCT cis rs9733 0.596 rs6678013 chr1:150623285 T/G cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs36051895 0.589 rs10491651 chr9:5200060 A/G cg02405213 chr9:5042618 JAK2 -0.75 -9.84 -0.66 3.08e-17 Pediatric autoimmune diseases; TGCT cis rs6089829 0.888 rs4809468 chr20:61673566 T/C cg18188782 chr20:61659543 NA 0.45 4.94 0.41 2.51e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs1005277 0.579 rs2474580 chr10:38398713 G/A cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4919044 0.808 rs9419763 chr10:94788965 G/A cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs2997447 0.846 rs3008226 chr1:26394997 A/C cg19633962 chr1:26362018 EXTL1 -0.68 -4.62 -0.38 9.47e-6 QRS complex (12-leadsum); TGCT cis rs6952808 1.000 rs4719319 chr7:1888094 G/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.63 -0.45 1.13e-7 Bipolar disorder and schizophrenia; TGCT cis rs992157 1.000 rs4791 chr2:219138940 C/T cg00012203 chr2:219082015 ARPC2 0.77 8.2 0.59 2.56e-13 Colorectal cancer; TGCT cis rs68170813 0.559 rs6951639 chr7:106817639 A/G cg02696742 chr7:106810147 HBP1 -0.7 -6.05 -0.48 1.59e-8 Coronary artery disease; TGCT cis rs6951245 0.580 rs77101766 chr7:1122438 A/G cg23708337 chr7:1209742 NA 0.45 5.04 0.41 1.62e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1005277 0.579 rs2474599 chr10:38438939 A/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.23 -0.59 2.17e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4689388 0.926 rs10937720 chr4:6295451 A/G cg25554036 chr4:6271136 WFS1 0.53 7.33 0.55 2.58e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7027203 0.828 rs4743934 chr9:96581893 A/G cg14598338 chr9:96623480 NA -0.61 -9.56 -0.65 1.43e-16 DNA methylation (variation); TGCT cis rs736408 0.500 rs2878762 chr3:52919002 T/C cg11645453 chr3:52864694 ITIH4 0.33 5.71 0.46 7.78e-8 Bipolar disorder; TGCT cis rs6061231 0.544 rs2427314 chr20:60973666 C/T cg24112000 chr20:60950667 NA -0.38 -5.09 -0.42 1.27e-6 Colorectal cancer; TGCT cis rs35146811 0.586 rs10267231 chr7:99595480 T/C cg13334819 chr7:99746414 C7orf59 -0.74 -6.4 -0.5 2.92e-9 Coronary artery disease; TGCT cis rs2839186 0.967 rs9637172 chr21:47685787 T/C cg13732083 chr21:47605072 C21orf56 0.36 4.57 0.38 1.14e-5 Testicular germ cell tumor; TGCT cis rs7772486 0.875 rs7761033 chr6:146356106 C/T cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7809950 0.862 rs58391518 chr7:107030787 T/C cg23024343 chr7:107201750 COG5 -0.31 -4.75 -0.39 5.55e-6 Coronary artery disease; TGCT cis rs9859260 0.744 rs3933 chr3:195784997 C/T cg02975922 chr3:195473998 MUC4 0.26 5.21 0.42 7.57e-7 Mean corpuscular volume; TGCT cis rs8056742 0.818 rs13330480 chr16:85091864 C/G cg00229868 chr16:85520891 NA -0.36 -5.18 -0.42 8.52e-7 Amyotrophic lateral sclerosis; TGCT cis rs11148252 0.500 rs342768 chr13:53208882 C/T cg00495681 chr13:53174319 NA 0.57 5.59 0.45 1.4e-7 Lewy body disease; TGCT cis rs7809950 0.906 rs62483723 chr7:107186358 A/C cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg13397359 chr6:42928475 GNMT 0.66 5.88 0.47 3.54e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg03351412 chr1:154909251 PMVK -0.47 -4.59 -0.38 1.09e-5 Prostate cancer; TGCT cis rs1580019 0.844 rs1901202 chr7:32503724 A/T cg06627557 chr7:32535165 LSM5;AVL9 0.87 8.48 0.61 5.56e-14 Cognitive ability; TGCT cis rs7975161 0.535 rs6539138 chr12:104735928 G/A cg25273343 chr12:104657179 TXNRD1 -0.34 -4.82 -0.4 4.16e-6 Toenail selenium levels; TGCT cis rs10876993 0.928 rs1678540 chr12:58065002 A/G cg15848620 chr12:58087721 OS9 -0.72 -5.91 -0.47 3.12e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg20007245 chr22:24372913 LOC391322 0.8 8.81 0.62 9.16e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11118844 0.744 rs10863656 chr1:221952703 T/A cg04222084 chr1:221915650 DUSP10 -0.78 -4.66 -0.39 8.03e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs2594989 0.943 rs9822446 chr3:11420780 C/G cg00170343 chr3:11313890 ATG7 0.64 4.89 0.4 3.04e-6 Circulating chemerin levels; TGCT cis rs10992471 0.756 rs10992303 chr9:95082804 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -6.31 -0.49 4.5e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs35883536 0.647 rs7535762 chr1:101047534 A/G cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT trans rs4957048 0.891 rs11960196 chr5:568857 C/A cg25482853 chr8:67687455 SGK3 1.1 8.74 0.62 1.34e-14 Ulcerative colitis; TGCT cis rs7027203 0.828 rs4744291 chr9:96598297 A/G cg14598338 chr9:96623480 NA -0.61 -9.54 -0.65 1.68e-16 DNA methylation (variation); TGCT cis rs67073037 0.955 rs12620330 chr2:29133688 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg07507251 chr3:52567010 NT5DC2 0.48 6.65 0.51 8.49e-10 Bipolar disorder; TGCT cis rs7172809 0.548 rs11853625 chr15:77505206 C/T cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs7959452 0.535 rs10784771 chr12:69621264 A/G cg11871910 chr12:69753446 YEATS4 0.62 5.98 0.47 2.24e-8 Blood protein levels; TGCT cis rs826838 1.000 rs11183214 chr12:38692938 C/T cg13010199 chr12:38710504 ALG10B 0.82 6.65 0.51 8.46e-10 Heart rate; TGCT cis rs3916 1.000 rs1799958 chr12:121176083 G/A cg21892295 chr12:121157589 UNC119B -0.23 -4.55 -0.38 1.27e-5 Urinary metabolites (H-NMR features); TGCT cis rs4689388 0.609 rs4688988 chr4:6287456 C/T cg14416269 chr4:6271139 WFS1 0.49 5.83 0.46 4.55e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12291225 0.679 rs11023170 chr11:14294909 A/G cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs7412746 0.611 rs4509581 chr1:150774465 A/G cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs3796619 1.000 rs28620427 chr4:1086247 T/G cg27284194 chr4:1044797 NA 0.46 4.53 0.38 1.36e-5 Recombination rate (males); TGCT cis rs12681288 0.723 rs11784252 chr8:1027964 T/C cg04851639 chr8:1020857 NA -0.3 -4.9 -0.4 2.97e-6 Schizophrenia; TGCT cis rs7208859 0.562 rs216408 chr17:28907757 C/G cg13385521 chr17:29058706 SUZ12P -0.7 -4.48 -0.37 1.69e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2486288 0.656 rs11637920 chr15:45550905 T/C cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs71435601 0.628 rs312985 chr2:21378805 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs807669 0.903 rs1780637 chr22:19178250 A/G cg02655711 chr22:19163373 SLC25A1 0.42 9.92 0.67 1.94e-17 Metabolite levels; TGCT cis rs10851411 0.817 rs1060265 chr15:42824582 T/C cg23803468 chr15:43513504 EPB42 0.29 5.38 0.44 3.52e-7 Glucose homeostasis traits; TGCT cis rs975752 0.867 rs11817486 chr10:102001771 C/T cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs9914988 0.887 rs11080072 chr17:27081160 G/T cg20469991 chr17:27169893 C17orf63 -0.66 -5.03 -0.41 1.65e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs362296 0.661 rs3121420 chr4:3264210 T/C cg06533319 chr4:3265114 C4orf44 0.23 4.46 0.37 1.82e-5 Parental longevity (mother's age at death); TGCT cis rs59698941 0.527 rs11742089 chr5:132178930 G/A cg21474247 chr5:131268130 NA 0.32 5.12 0.42 1.15e-6 Apolipoprotein A-IV levels; TGCT cis rs9300255 0.602 rs941305 chr12:123715266 T/C cg00376283 chr12:123451042 ABCB9 0.67 5.26 0.43 6.13e-7 Neutrophil percentage of white cells; TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg21280719 chr6:42927975 GNMT -0.38 -4.63 -0.38 9.09e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9467603 0.592 rs1184498 chr6:25864882 G/C cg12310025 chr6:25882481 NA -0.71 -4.56 -0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT trans rs12339966 0.653 rs1489175 chr9:11278380 G/T cg07173112 chr1:1114698 TTLL10 -0.33 -6.69 -0.51 6.89e-10 Systolic blood pressure; TGCT cis rs9341808 0.718 rs2143887 chr6:80917287 T/C cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs13191362 0.938 rs35211042 chr6:162998703 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs17221829 0.733 rs10501708 chr11:89394435 T/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.66 -0.39 7.89e-6 Anxiety in major depressive disorder; TGCT trans rs1415174 0.916 rs12116920 chr1:87839207 T/C cg23065576 chr20:25207247 ENTPD6 -0.27 -6.64 -0.51 8.97e-10 Breast cancer; TGCT cis rs9467773 0.869 rs742090 chr6:26415637 A/C cg24010402 chr6:26660753 ZNF322A 0.23 4.46 0.37 1.84e-5 Intelligence (multi-trait analysis); TGCT cis rs17253792 0.822 rs75897560 chr14:56090965 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3806843 0.576 rs246021 chr5:140334504 C/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9473924 0.542 rs9473922 chr6:50831792 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs713587 0.563 rs2033655 chr2:25101092 C/T cg01884057 chr2:25150051 NA 0.28 5.19 0.42 8.44e-7 Body mass index in non-asthmatics; TGCT cis rs1056107 0.572 rs10817334 chr9:115164057 G/C cg02332936 chr9:115140584 NA -0.26 -4.5 -0.37 1.55e-5 Colorectal cancer; TGCT cis rs10992471 0.528 rs4744133 chr9:95226702 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.51 -4.62 -0.38 9.42e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs868036 0.681 rs4776976 chr15:68103291 C/T cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs8014204 0.533 rs12889955 chr14:75172999 G/A cg06637938 chr14:75390232 RPS6KL1 0.61 5.51 0.44 1.98e-7 Caffeine consumption; TGCT cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg13409248 chr3:40428643 ENTPD3 0.55 4.49 0.37 1.61e-5 Renal cell carcinoma; TGCT cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg11890956 chr21:40555474 PSMG1 -0.73 -6.98 -0.53 1.59e-10 Menarche (age at onset); TGCT cis rs1570884 0.516 rs9526580 chr13:50164023 C/G cg03651054 chr13:50194643 NA -0.35 -5.72 -0.46 7.45e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs7666738 0.546 rs11097591 chr4:98910173 G/A cg05340658 chr4:99064831 C4orf37 0.6 6.62 0.51 9.9e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1371867 0.875 rs1962901 chr8:101326428 A/G cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs611744 0.967 rs536860 chr8:109230722 A/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs17826219 0.636 rs4055314 chr17:29079769 T/C cg13385521 chr17:29058706 SUZ12P 0.79 4.8 0.4 4.47e-6 Body mass index; TGCT cis rs61931739 0.500 rs12829125 chr12:34314789 A/G cg06521331 chr12:34319734 NA -0.3 -4.45 -0.37 1.87e-5 Morning vs. evening chronotype; TGCT cis rs28595532 0.841 rs115851302 chr4:119776504 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs8016982 0.674 rs28890880 chr14:81708031 A/G cg01989461 chr14:81687754 GTF2A1 0.77 7.19 0.54 5.35e-11 Schizophrenia; TGCT cis rs28714278 0.609 rs34513107 chr15:40302425 G/A cg21830797 chr15:40226279 EIF2AK4 -0.54 -4.88 -0.4 3.19e-6 Mean corpuscular hemoglobin; TGCT cis rs12971120 0.891 rs2278159 chr18:72178161 T/C cg25817165 chr18:72167213 CNDP2 -0.27 -4.65 -0.39 8.37e-6 Refractive error; TGCT cis rs6909279 0.933 rs9479072 chr6:151890789 C/T cg14416726 chr6:151773293 C6orf211;RMND1 0.52 4.49 0.37 1.59e-5 Bone mineral density; TGCT cis rs3780378 0.902 rs2381195 chr9:5145887 T/C cg02405213 chr9:5042618 JAK2 -0.59 -7.64 -0.57 5.06e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs4819052 0.851 rs10470246 chr21:46659017 C/G cg06618935 chr21:46677482 NA -0.36 -5.71 -0.46 7.76e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4699052 0.625 rs7695593 chr4:104263783 A/T cg16532752 chr4:104119610 CENPE -0.5 -4.92 -0.4 2.71e-6 Testicular germ cell tumor; TGCT cis rs35785195 0.633 rs1035774 chr12:114230856 G/C cg11070030 chr12:114232702 NA 0.26 4.46 0.37 1.79e-5 Daytime sleep phenotypes; TGCT cis rs6570726 0.764 rs9322028 chr6:145895797 G/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs892961 0.932 rs11658267 chr17:75411884 C/T cg05865280 chr17:75406074 SEPT9 -0.28 -6.76 -0.52 4.82e-10 Airflow obstruction; TGCT cis rs9611565 0.592 rs9611613 chr22:41961831 T/C cg06481639 chr22:41940642 POLR3H -0.67 -5.71 -0.46 7.87e-8 Vitiligo; TGCT cis rs9341808 0.718 rs9343971 chr6:80882056 C/T cg08355045 chr6:80787529 NA 0.32 5.64 0.45 1.11e-7 Sitting height ratio; TGCT cis rs35306767 0.807 rs61831436 chr10:837882 G/A cg26597838 chr10:835615 NA 0.8 11.79 0.73 5.55e-22 Eosinophil percentage of granulocytes; TGCT cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg06634786 chr22:41940651 POLR3H 0.88 8.54 0.61 4.05e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs4366490 0.687 rs1944040 chr11:62902984 C/T cg21002970 chr11:62369079 MTA2 0.74 5.2 0.42 7.81e-7 Conotruncal heart defects; TGCT cis rs838147 0.505 rs1688264 chr19:49209560 T/G cg05248581 chr19:49925731 PTH2 0.41 4.51 0.38 1.5e-5 Dietary macronutrient intake; TGCT cis rs7727544 0.735 rs273914 chr5:131660431 A/T cg24060327 chr5:131705240 SLC22A5 -0.56 -6.38 -0.5 3.2e-9 Blood metabolite levels; TGCT cis rs2204008 0.527 rs8189480 chr12:38345648 C/T cg26384229 chr12:38710491 ALG10B -0.51 -4.48 -0.37 1.68e-5 Bladder cancer; TGCT cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg20607798 chr8:58055168 NA 0.62 5.19 0.42 8.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.697 rs7269866 chr20:30232504 G/A cg18721089 chr20:30220636 NA -0.53 -5.43 -0.44 2.86e-7 Mean corpuscular hemoglobin; TGCT cis rs986417 0.901 rs10782440 chr14:61031648 G/C cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs1552244 0.882 rs113268531 chr3:10167069 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.61 -0.51 1.02e-9 Alzheimer's disease; TGCT trans rs208520 0.690 rs7764570 chr6:66827600 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.91 -9.02 -0.63 2.89e-15 Exhaled nitric oxide output; TGCT cis rs6089584 0.888 rs6587283 chr20:60613727 A/C cg06108461 chr20:60628389 TAF4 -0.69 -10.56 -0.69 5.46e-19 Body mass index; TGCT cis rs7819412 0.618 rs34772085 chr8:10964906 C/T cg21775007 chr8:11205619 TDH -0.54 -5.29 -0.43 5.43e-7 Triglycerides; TGCT cis rs2797160 1.000 rs2211420 chr6:125995549 A/G cg05901451 chr6:126070800 HEY2 -0.74 -6.49 -0.5 1.84e-9 Endometrial cancer; TGCT cis rs36051895 0.530 rs6476951 chr9:5221614 A/G cg02405213 chr9:5042618 JAK2 -0.69 -8.89 -0.62 5.91e-15 Pediatric autoimmune diseases; TGCT cis rs694739 0.930 rs574087 chr11:64102948 A/G cg23796481 chr11:64053134 BAD;GPR137 0.7 7.4 0.55 1.76e-11 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9733 0.596 rs6678013 chr1:150623285 T/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs8076336 1 rs8076336 chr17:18212614 A/C cg26763362 chr17:18266135 SHMT1 0.33 4.69 0.39 7.19e-6 Parental longevity (combined parental age at death); TGCT cis rs1538970 0.816 rs11211123 chr1:45957609 G/A cg05343316 chr1:45956843 TESK2 0.81 6.64 0.51 8.93e-10 Platelet count; TGCT cis rs2239547 0.522 rs2336669 chr3:52994138 C/T cg11645453 chr3:52864694 ITIH4 -0.32 -5.27 -0.43 5.93e-7 Schizophrenia; TGCT cis rs7829975 0.514 rs2945873 chr8:8260445 C/T cg06636001 chr8:8085503 FLJ10661 0.71 6.11 0.48 1.16e-8 Mood instability; TGCT cis rs7267979 0.932 rs2387891 chr20:25470328 C/G cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4953076 0.533 rs1551315 chr2:44407618 G/A cg00619915 chr2:44497795 NA -0.22 -5.02 -0.41 1.72e-6 Height; TGCT cis rs5769765 0.955 rs9616367 chr22:50303515 A/C cg15316289 chr22:50310904 ALG12;CRELD2 0.41 5.84 0.46 4.39e-8 Schizophrenia; TGCT cis rs2224391 1.000 rs9504369 chr6:5261575 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.8 -6.12 -0.48 1.13e-8 Height; TGCT cis rs3820068 0.705 rs41486146 chr1:15900517 A/G cg05660106 chr1:15850417 CASP9 -1.13 -13.14 -0.76 3.06e-25 Systolic blood pressure; TGCT cis rs2180341 0.960 rs1964130 chr6:127677391 C/G cg27446573 chr6:127587934 RNF146 1.08 8.81 0.62 9.1e-15 Breast cancer; TGCT cis rs6951245 0.554 rs58210047 chr7:1149381 G/A cg23708337 chr7:1209742 NA 0.44 4.97 0.41 2.16e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10540 1.000 rs10540 chr11:494662 G/A cg03934478 chr11:495069 RNH1 0.35 5.82 0.46 4.66e-8 Body mass index; TGCT cis rs4455778 0.580 rs4598208 chr7:49084584 G/A cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs2243480 0.908 rs313822 chr7:65573939 G/A cg20637647 chr7:64974828 NA 0.84 4.85 0.4 3.63e-6 Diabetic kidney disease; TGCT cis rs3008870 1.000 rs11208979 chr1:67442275 C/T cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs6089829 0.962 rs2314131 chr20:61665225 A/G cg08045932 chr20:61659980 NA 0.37 5.66 0.45 9.97e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1975974 0.748 rs67473406 chr17:21726745 G/A cg18423549 chr17:21743878 NA -0.55 -5.0 -0.41 1.93e-6 Psoriasis; TGCT cis rs11190604 0.666 rs7084768 chr10:102200497 T/C cg16342193 chr10:102329863 NA 0.4 5.05 0.41 1.56e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs6570726 0.791 rs398408 chr6:145801020 G/A cg05347473 chr6:146136440 FBXO30 0.51 4.72 0.39 6.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467711 0.606 rs9379854 chr6:26362854 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs561341 0.710 rs9900031 chr17:30199537 T/C cg20587970 chr11:113659929 NA 0.83 8.7 0.62 1.71e-14 Hip circumference adjusted for BMI; TGCT cis rs9911578 0.967 rs6503893 chr17:57149695 G/A cg12560992 chr17:57184187 TRIM37 0.79 9.71 0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.783 rs12603969 chr17:47034419 A/G cg27201301 chr17:47039149 GIP 0.25 4.47 0.37 1.72e-5 Type 2 diabetes; TGCT cis rs11718455 0.960 rs6781618 chr3:44001933 C/T cg08738300 chr3:44038990 NA 0.85 6.41 0.5 2.72e-9 Coronary artery disease; TGCT cis rs11711311 1.000 rs12636577 chr3:113497507 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg25660036 chr4:7070649 GRPEL1 -0.67 -5.81 -0.46 4.85e-8 Monocyte percentage of white cells; TGCT cis rs8067545 1.000 rs4925065 chr17:19914546 C/T cg13482628 chr17:19912719 NA 0.55 4.79 0.4 4.69e-6 Schizophrenia; TGCT cis rs17473412 1.000 rs17407759 chr5:122697295 C/G cg15125798 chr5:122621645 NA -0.57 -5.13 -0.42 1.08e-6 Total body bone mineral density; TGCT cis rs3784262 0.528 rs8027188 chr15:58334799 C/T cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.48 -0.5 1.99e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4906332 0.966 rs2065016 chr14:103879656 T/A cg26031613 chr14:104095156 KLC1 -0.51 -4.63 -0.38 9.17e-6 Coronary artery disease; TGCT cis rs4803468 1.000 rs3816037 chr19:41918009 C/T cg09537434 chr19:41945824 ATP5SL -0.91 -10.9 -0.7 8.11e-20 Height; TGCT cis rs2147959 1.000 rs2147959 chr1:228644232 A/T cg22700015 chr1:228743131 NA -0.57 -4.5 -0.37 1.55e-5 Adult asthma; TGCT cis rs10170846 0.800 rs10180462 chr2:223526385 C/T cg25565276 chr2:223520875 FARSB 0.55 4.58 0.38 1.11e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs4953076 0.573 rs920519 chr2:44452344 T/C cg00619915 chr2:44497795 NA -0.23 -5.08 -0.41 1.36e-6 Height; TGCT cis rs4819052 0.808 rs11909411 chr21:46676556 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6840360 0.615 rs12641438 chr4:152607586 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.13 -0.48 1.1e-8 Intelligence (multi-trait analysis); TGCT cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg12379764 chr21:47803548 PCNT -0.48 -4.64 -0.38 8.75e-6 Testicular germ cell tumor; TGCT cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg02073558 chr3:44770973 ZNF501 0.72 7.07 0.54 1.02e-10 Depressive symptoms; TGCT cis rs3733585 0.631 rs4697925 chr4:10124330 G/C cg00071950 chr4:10020882 SLC2A9 -0.49 -5.05 -0.41 1.53e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs35306767 0.903 rs12249634 chr10:872744 G/A cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs4076764 1.000 rs7540279 chr1:163429970 A/T cg24596788 chr1:163392923 NA -0.17 -4.75 -0.39 5.46e-6 Motion sickness; TGCT cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.807 rs4955416 chr3:49108428 T/C cg05785598 chr3:49045655 WDR6 0.39 4.5 0.37 1.56e-5 Menarche (age at onset); TGCT cis rs889312 0.500 rs832585 chr5:56125904 T/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Breast cancer;Breast cancer (early onset); TGCT trans rs4650994 0.544 rs2811311 chr1:178617337 A/G cg05059571 chr16:84539110 KIAA1609 0.51 9.84 0.66 3.04e-17 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7017914 0.902 rs10504481 chr8:71699517 T/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.94 -0.41 2.52e-6 Bone mineral density; TGCT cis rs7439150 0.954 rs60309797 chr4:155477548 G/A cg22130008 chr4:155548532 NA -0.43 -5.43 -0.44 2.87e-7 Fibrinogen levels; TGCT cis rs6424115 1.000 rs7519554 chr1:24154566 T/A cg15997130 chr1:24165203 NA -0.92 -10.57 -0.69 5.26e-19 Immature fraction of reticulocytes; TGCT cis rs10779751 0.734 rs910660 chr1:11130643 C/T cg08854313 chr1:11322531 MTOR -0.82 -7.04 -0.53 1.19e-10 Body mass index; TGCT cis rs4319547 0.614 rs10846764 chr12:122874297 T/C cg08088222 chr12:122070432 ORAI1 -0.25 -4.49 -0.37 1.58e-5 Body mass index; TGCT cis rs7582180 0.606 rs12618908 chr2:100947026 A/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs6695640 0.854 rs2800699 chr1:17733136 C/T cg25979543 chr1:17888104 ARHGEF10L -0.25 -4.5 -0.37 1.54e-5 Mean platelet volume; TGCT cis rs4911259 0.552 rs6057663 chr20:31463071 G/T cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs42648 0.837 rs7786771 chr7:89924767 G/A cg25739043 chr7:89950458 NA -0.71 -7.17 -0.54 5.81e-11 Homocysteine levels; TGCT cis rs9443645 0.901 rs9352666 chr6:79572184 C/G cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs4523957 0.651 rs9894613 chr17:2071058 C/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2797780 0.704 rs16889902 chr6:37516378 C/T cg00985040 chr6:37553208 NA 0.27 4.63 0.38 9.07e-6 Systemic lupus erythematosus; TGCT cis rs7586879 0.598 rs6545806 chr2:25124348 G/A cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs7104764 1.000 rs2272565 chr11:244414 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs3820068 0.603 rs72645887 chr1:15929905 G/C cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs10461617 0.617 rs79742142 chr5:56104377 A/G cg20203395 chr5:56204925 C5orf35 -0.61 -5.25 -0.43 6.32e-7 Type 2 diabetes; TGCT cis rs12701220 0.901 rs12701710 chr7:1090396 A/G cg07217954 chr7:1067459 C7orf50 0.48 4.81 0.4 4.26e-6 Bronchopulmonary dysplasia; TGCT cis rs11098499 0.865 rs3956464 chr4:120256764 T/C cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Corneal astigmatism; TGCT cis rs1497406 0.744 rs6677710 chr1:16507618 A/G cg20430773 chr1:16534157 ARHGEF19 0.51 5.86 0.47 3.93e-8 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6543140 0.865 rs6760275 chr2:103079607 C/T cg09003973 chr2:102972529 NA 0.55 4.56 0.38 1.2e-5 Blood protein levels; TGCT cis rs7635838 0.586 rs347617 chr3:11278211 C/T cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs6988636 1.000 rs16898084 chr8:124190377 A/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs9467711 1.000 rs34569761 chr6:26334306 A/G cg02458000 chr6:26745757 NA -1.1 -6.09 -0.48 1.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs319204 1.000 rs167635 chr5:146260896 T/C cg13983063 chr5:146258615 PPP2R2B 0.33 4.77 0.39 5.05e-6 Schizophrenia; TGCT cis rs9291683 0.588 rs13133766 chr4:10019732 C/T cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Bone mineral density; TGCT cis rs4727027 0.727 rs3801980 chr7:148878620 T/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.58 5.13 0.42 1.09e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs4713118 0.824 rs9468223 chr6:27740666 C/T cg02458000 chr6:26745757 NA -0.57 -4.97 -0.41 2.18e-6 Parkinson's disease; TGCT cis rs4242434 0.672 rs900267 chr8:22485258 T/C cg03733263 chr8:22462867 KIAA1967 0.98 13.14 0.76 2.97e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs137699 0.695 rs137653 chr22:39732171 A/G cg05872129 chr22:39784769 NA 0.58 4.88 0.4 3.25e-6 IgG glycosylation; TGCT cis rs10791097 0.694 rs7107595 chr11:130758556 C/T cg05962950 chr11:130786565 SNX19 0.91 11.83 0.73 4.55e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs66573146 1.000 rs55913461 chr4:7017509 C/T cg05069807 chr4:6945702 TBC1D14 0.37 5.2 0.42 8.07e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs1129187 0.935 rs9462859 chr6:42946943 G/A cg05552183 chr6:42928497 GNMT 0.54 4.68 0.39 7.25e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7086627 0.515 rs10887901 chr10:82210581 G/A cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs7937682 0.921 rs11213945 chr11:111461003 A/G cg09085632 chr11:111637200 PPP2R1B 0.88 7.27 0.55 3.56e-11 Primary sclerosing cholangitis; TGCT cis rs782590 0.522 rs12329050 chr2:55894428 G/A cg03859395 chr2:55845619 SMEK2 -0.66 -6.39 -0.5 3.05e-9 Metabolic syndrome; TGCT cis rs6088580 0.634 rs4911420 chr20:32998654 A/G cg08999081 chr20:33150536 PIGU -0.28 -5.58 -0.45 1.47e-7 Glomerular filtration rate (creatinine); TGCT cis rs546131 0.890 rs496558 chr11:34826425 C/T cg06937548 chr11:34938143 PDHX;APIP 0.66 5.95 0.47 2.59e-8 Lung disease severity in cystic fibrosis; TGCT cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 5.73 0.46 7.29e-8 Height; TGCT cis rs13191362 1.000 rs35583420 chr6:163214327 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.76 4.78 0.39 4.85e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6906287 0.647 rs11153752 chr6:118834771 A/T cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7926906 1.000 rs2177680 chr11:90532256 A/T cg26138821 chr11:89956704 CHORDC1 -0.5 -5.33 -0.43 4.44e-7 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.859 rs9927529 chr16:1619488 C/T cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.53 -0.44 1.84e-7 Coronary artery disease; TGCT cis rs12049351 0.774 rs6670553 chr1:229635867 A/G cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs601339 1.000 rs509548 chr12:123181855 T/A cg11919336 chr12:123188078 GPR109A 0.64 7.82 0.57 2.01e-12 Adiponectin levels; TGCT cis rs6674176 0.597 rs4660262 chr1:44382524 G/A cg13606994 chr1:44402422 ARTN -0.51 -5.52 -0.44 1.91e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs651907 0.541 rs2925325 chr3:101630668 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.5 4.86 0.4 3.54e-6 Colorectal cancer; TGCT trans rs9951602 0.573 rs8098953 chr18:76648734 A/G cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs3766606 0.505 rs67002863 chr1:7923478 G/A cg26816564 chr1:7831052 VAMP3 0.68 5.22 0.42 7.18e-7 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; TGCT cis rs2836974 0.897 rs35064900 chr21:40555492 A/G cg17971929 chr21:40555470 PSMG1 0.96 9.01 0.63 3.05e-15 Cognitive function; TGCT cis rs6964587 1.000 rs9784993 chr7:91672403 G/A cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs7119 0.634 rs2682922 chr15:77865006 A/C cg27398640 chr15:77910606 LINGO1 0.25 4.63 0.38 9.12e-6 Type 2 diabetes; TGCT trans rs11722228 0.508 rs3796826 chr4:10092728 G/A cg26043149 chr18:55253948 FECH 1.16 11.23 0.71 1.26e-20 Gout;Urate levels;Serum uric acid levels; TGCT trans rs7618501 0.602 rs2071206 chr3:50160109 G/A cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs748404 0.660 rs689767 chr15:43722077 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs7258465 1.000 rs4808133 chr19:18608518 C/A cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs2274459 0.500 rs12206173 chr6:33601671 G/C cg11783815 chr6:33558433 C6orf227 0.33 4.63 0.38 8.95e-6 Obesity (extreme); TGCT cis rs7178572 0.568 rs7175674 chr15:77670910 C/T cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs4253772 0.550 rs9615949 chr22:46722531 C/T cg24881330 chr22:46731750 TRMU 0.99 5.45 0.44 2.64e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs7666738 0.830 rs13138438 chr4:99050545 C/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2797160 1.000 rs1739375 chr6:126012013 T/C cg05901451 chr6:126070800 HEY2 0.72 5.91 0.47 3.15e-8 Endometrial cancer; TGCT cis rs7474896 0.583 rs34185758 chr10:37990854 T/C cg13720705 chr10:37990370 NA 0.4 5.69 0.46 8.61e-8 Obesity (extreme); TGCT cis rs7567389 0.626 rs11683344 chr2:127956252 A/C cg09760422 chr2:128146352 NA 0.36 4.63 0.38 8.95e-6 Self-rated health; TGCT cis rs12681287 0.608 rs1135451 chr8:87483608 T/C cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs7043114 0.525 rs2025388 chr9:95128740 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.56 -0.45 1.58e-7 Height; TGCT cis rs9916302 0.904 rs588193 chr17:37440439 A/C cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs6545883 0.783 rs7579651 chr2:61800279 C/G cg15711740 chr2:61764176 XPO1 -0.59 -5.7 -0.46 8.42e-8 Tuberculosis; TGCT cis rs854765 0.583 rs11078404 chr17:17820487 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.69 0.57 3.91e-12 Total body bone mineral density; TGCT cis rs4523957 0.651 rs9908373 chr17:2086534 G/A cg16513277 chr17:2031491 SMG6 -0.21 -4.62 -0.38 9.43e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7267979 0.966 rs6083855 chr20:25405118 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11167764 0.895 rs13189044 chr5:141471431 A/C cg23435118 chr5:141488016 NDFIP1 -0.28 -4.63 -0.38 9.14e-6 Crohn's disease; TGCT cis rs6693567 0.545 rs2012751 chr1:150438266 T/C cg09579323 chr1:150459698 TARS2 0.52 4.62 0.38 9.55e-6 Migraine; TGCT cis rs79387448 0.655 rs76930359 chr2:102924684 G/A cg09003973 chr2:102972529 NA 1.34 8.26 0.6 1.89e-13 Gut microbiota (bacterial taxa); TGCT cis rs7635838 0.684 rs2606750 chr3:11372151 T/C cg00170343 chr3:11313890 ATG7 0.6 5.86 0.47 3.86e-8 HDL cholesterol; TGCT cis rs4808199 0.947 rs10404728 chr19:19595014 C/T cg03709012 chr19:19516395 GATAD2A 0.97 7.53 0.56 9.28e-12 Nonalcoholic fatty liver disease; TGCT cis rs4689388 0.926 rs4416547 chr4:6293967 G/A cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7017914 0.905 rs3098881 chr8:71939690 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs12791968 1.000 rs11038240 chr11:45002878 A/G cg11846598 chr11:44996168 LOC221122 0.35 6.83 0.52 3.43e-10 Inhibitory control; TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg16145915 chr7:1198662 ZFAND2A -0.6 -8.51 -0.61 4.69e-14 Longevity;Endometriosis; TGCT cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg04267008 chr7:1944627 MAD1L1 -0.37 -4.85 -0.4 3.56e-6 Bipolar disorder and schizophrenia; TGCT cis rs6089829 0.926 rs73921625 chr20:61660891 C/T cg08045932 chr20:61659980 NA -0.31 -4.47 -0.37 1.76e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs2153535 0.580 rs7748455 chr6:8453625 C/T cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs137699 1.000 rs5757632 chr22:39756097 A/C cg24399712 chr22:39784796 NA -0.67 -5.99 -0.47 2.08e-8 IgG glycosylation; TGCT cis rs1153858 1.000 rs61365925 chr15:45650311 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs56036086 0.887 rs11912419 chr22:50627188 C/T cg01548456 chr22:50352384 NA 0.36 5.15 0.42 9.84e-7 Platelet count;Plateletcrit; TGCT cis rs7412746 0.658 rs7521719 chr1:150913134 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs9611565 0.659 rs9611610 chr22:41949259 A/G cg06481639 chr22:41940642 POLR3H -0.75 -6.8 -0.52 3.92e-10 Vitiligo; TGCT cis rs17253792 0.822 rs75049893 chr14:56089158 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7119038 0.818 rs73003215 chr11:118649512 G/A cg19308663 chr11:118741387 NA 0.27 5.51 0.44 2.02e-7 Sjögren's syndrome; TGCT cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg06640241 chr16:89574553 SPG7 -0.72 -7.89 -0.58 1.36e-12 Multiple myeloma (IgH translocation); TGCT cis rs4727027 0.769 rs10952797 chr7:148816722 A/T cg23583168 chr7:148888333 NA -0.72 -9.17 -0.64 1.3e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2302464 1.000 rs16892276 chr4:15728237 T/G cg18497811 chr4:14860861 NA -0.49 -4.5 -0.37 1.57e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs6088580 0.619 rs1205335 chr20:32927507 C/T cg08999081 chr20:33150536 PIGU -0.25 -4.85 -0.4 3.66e-6 Glomerular filtration rate (creatinine); TGCT cis rs478304 0.654 rs12289836 chr11:65436888 C/T cg27068330 chr11:65405492 SIPA1 1.02 11.5 0.72 2.89e-21 Acne (severe); TGCT cis rs7959452 0.590 rs6581889 chr12:69757429 T/C cg20891283 chr12:69753455 YEATS4 0.83 8.61 0.61 2.8e-14 Blood protein levels; TGCT cis rs2456568 0.771 rs2102333 chr11:93634749 G/A cg16099599 chr11:93583650 C11orf90 -0.4 -4.98 -0.41 2.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4499344 0.633 rs259229 chr19:33134425 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.84 -9.18 -0.64 1.2e-15 Mean platelet volume; TGCT cis rs7804356 0.705 rs10250223 chr7:26821320 C/A cg03456212 chr7:26904342 SKAP2 -0.54 -4.46 -0.37 1.82e-5 Type 1 diabetes; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg02953382 chr22:24373134 LOC391322 -0.78 -8.12 -0.59 4.06e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7211079 0.879 rs66693363 chr17:78128935 G/A cg09238746 chr17:78121135 EIF4A3 -0.72 -5.9 -0.47 3.18e-8 Myocardial infarction; TGCT cis rs67073037 0.955 rs4389288 chr2:29140711 G/A cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs1670533 1.000 rs6821725 chr4:1060360 C/G cg20887711 chr4:1340912 KIAA1530 0.65 5.07 0.41 1.38e-6 Recombination rate (females); TGCT cis rs4285028 0.948 rs13089878 chr3:121703895 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs11190604 1.000 rs10883500 chr10:102238324 T/G cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg13695892 chr22:41940480 POLR3H -0.9 -9.01 -0.63 3.17e-15 Vitiligo; TGCT cis rs10504229 1.000 rs113379801 chr8:58173686 C/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs67311347 1.000 rs56992941 chr3:40472434 A/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs2019216 0.500 rs1877497 chr17:21940171 C/T cg22648282 chr17:21454238 C17orf51 -0.58 -4.95 -0.41 2.37e-6 Pelvic organ prolapse; TGCT cis rs78707713 0.560 rs12784882 chr10:71230334 C/G cg12610070 chr10:71211762 TSPAN15 -0.62 -7.31 -0.55 2.83e-11 Venous thromboembolism; TGCT cis rs4689592 0.587 rs6825954 chr4:7074226 T/C cg25660036 chr4:7070649 GRPEL1 -0.64 -5.44 -0.44 2.77e-7 Monocyte percentage of white cells; TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg25767906 chr1:53392781 SCP2 -0.57 -6.81 -0.52 3.8e-10 Monocyte count; TGCT cis rs7937682 0.575 rs12808601 chr11:111776066 G/A cg09085632 chr11:111637200 PPP2R1B 0.97 10.03 0.67 1.06e-17 Primary sclerosing cholangitis; TGCT cis rs9913156 0.793 rs55884013 chr17:4579301 G/A cg19197139 chr17:4613644 ARRB2 0.87 7.5 0.56 1.09e-11 Lymphocyte counts; TGCT cis rs4076764 0.958 rs12022261 chr1:163398422 A/G cg24596788 chr1:163392923 NA -0.17 -4.74 -0.39 5.85e-6 Motion sickness; TGCT cis rs11190604 1.000 rs4919469 chr10:102298855 C/A cg23241863 chr10:102295624 HIF1AN 0.69 5.1 0.42 1.24e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs854765 0.583 rs12603148 chr17:17865257 C/T cg09796270 chr17:17721594 SREBF1 0.23 4.56 0.38 1.22e-5 Total body bone mineral density; TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg26338869 chr17:61819248 STRADA 0.53 4.94 0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs2120019 0.935 rs34913788 chr15:75372617 A/C cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT trans rs7726839 0.574 rs72705017 chr5:623733 G/A cg11887960 chr12:57824829 NA 1.19 9.29 0.64 6.45e-16 Obesity-related traits; TGCT cis rs4072705 0.614 rs1570581 chr9:127234059 A/G cg13476313 chr9:127244764 NR5A1 0.29 4.47 0.37 1.72e-5 Menarche (age at onset); TGCT cis rs13256369 0.802 rs13281933 chr8:8562665 C/A cg17143192 chr8:8559678 CLDN23 0.56 5.31 0.43 4.9e-7 Obesity-related traits; TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg24503407 chr1:205819492 PM20D1 0.59 8.22 0.59 2.3e-13 Menarche (age at onset); TGCT trans rs7819412 0.811 rs2409691 chr8:10943276 C/T cg15556689 chr8:8085844 FLJ10661 -0.77 -7.44 -0.56 1.45e-11 Triglycerides; TGCT cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg07220782 chr6:26987966 LOC100270746;C6orf41 0.41 4.57 0.38 1.14e-5 Schizophrenia; TGCT cis rs17826219 0.636 rs2449770 chr17:29101064 G/T cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Body mass index; TGCT cis rs7726839 0.540 rs4957081 chr5:646418 G/C cg20362242 chr5:692897 TPPP 0.5 4.57 0.38 1.17e-5 Obesity-related traits; TGCT cis rs12497850 0.764 rs6784111 chr3:49178846 T/C cg18654377 chr3:49208889 KLHDC8B -0.38 -4.81 -0.4 4.25e-6 Parkinson's disease; TGCT cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg20887711 chr4:1340912 KIAA1530 0.92 8.35 0.6 1.13e-13 Longevity; TGCT cis rs4975709 0.589 rs1466606 chr5:1865055 C/T cg07747251 chr5:1868357 NA 0.39 5.75 0.46 6.7e-8 Cardiovascular disease risk factors; TGCT cis rs7666738 0.791 rs34088022 chr4:99001508 G/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9322193 0.923 rs11155670 chr6:149966128 C/G cg13206674 chr6:150067644 NUP43 0.51 4.45 0.37 1.91e-5 Lung cancer; TGCT cis rs4808199 0.895 rs10403731 chr19:19469296 G/A cg03709012 chr19:19516395 GATAD2A 0.84 6.72 0.52 5.97e-10 Nonalcoholic fatty liver disease; TGCT cis rs514406 0.621 rs1930306 chr1:53195686 C/G cg08859206 chr1:53392774 SCP2 0.34 4.82 0.4 4.1e-6 Monocyte count; TGCT cis rs8036030 0.604 rs11856835 chr15:74716174 G/A cg10253484 chr15:75165896 SCAMP2 -0.59 -5.3 -0.43 5.18e-7 Airflow obstruction; TGCT trans rs10953454 1.000 rs17777379 chr7:104491000 G/A cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs858239 0.601 rs11984129 chr7:23152677 A/G cg05602783 chr7:23145260 KLHL7 -0.62 -5.24 -0.43 6.55e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs17253792 0.822 rs10133962 chr14:56066088 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs5769765 0.954 rs5769762 chr22:50264042 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs2692947 0.644 rs1168968 chr2:96825363 C/T cg22654517 chr2:96458247 NA 0.24 5.08 0.41 1.36e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4499344 0.730 rs369859 chr19:33104305 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg08280861 chr8:58055591 NA 0.55 6.12 0.48 1.13e-8 Developmental language disorder (linguistic errors); TGCT cis rs853679 0.517 rs9393894 chr6:28112562 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.04 0.41 1.61e-6 Depression; TGCT cis rs7940866 0.801 rs10894296 chr11:130840433 T/G cg12179176 chr11:130786555 SNX19 0.62 5.93 0.47 2.75e-8 Schizophrenia; TGCT cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg20637647 chr7:64974828 NA 0.95 5.8 0.46 5.3e-8 Diabetic kidney disease; TGCT cis rs35160687 0.865 rs10189492 chr2:86478902 G/A cg04877910 chr2:85804641 VAMP8 0.34 4.48 0.37 1.67e-5 Night sleep phenotypes; TGCT cis rs4285028 0.948 rs34543553 chr3:121675637 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs2180341 0.521 rs12203812 chr6:127617816 A/T cg24812749 chr6:127587940 RNF146 0.61 5.16 0.42 9.54e-7 Breast cancer; TGCT cis rs7833790 0.724 rs6473311 chr8:82726682 G/A cg27398817 chr8:82754497 SNX16 -0.67 -5.34 -0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs9549367 0.577 rs3024711 chr13:113813268 A/G cg18105134 chr13:113819100 PROZ -0.46 -7.31 -0.55 2.85e-11 Platelet distribution width; TGCT cis rs2153535 0.580 rs9505458 chr6:8479215 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2066819 1.000 rs41363748 chr12:56696056 C/T cg26714650 chr12:56694279 CS 1.36 6.06 0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg21724239 chr8:58056113 NA 0.39 5.25 0.43 6.46e-7 Developmental language disorder (linguistic errors); TGCT cis rs1801251 0.656 rs10211596 chr2:233699415 C/T cg08000102 chr2:233561755 GIGYF2 -0.59 -6.75 -0.52 5.08e-10 Coronary artery disease; TGCT cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs4148883 0.689 rs2851275 chr4:100024883 A/G cg12011299 chr4:100065546 ADH4 0.37 5.69 0.45 8.77e-8 Alcohol dependence; TGCT cis rs4819052 0.851 rs13052344 chr21:46676101 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs57994353 0.600 rs10870172 chr9:139319469 G/A cg13741927 chr9:139327495 INPP5E -0.26 -5.73 -0.46 7.13e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs7027203 0.797 rs57882762 chr9:96580825 T/G cg13679303 chr9:96623674 NA -0.66 -10.49 -0.69 8e-19 DNA methylation (variation); TGCT cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10089 0.953 rs1432614 chr5:127416919 A/G cg19767477 chr5:127420684 SLC12A2 -0.46 -4.74 -0.39 5.77e-6 Ileal carcinoids; TGCT cis rs9527 0.614 rs2153774 chr10:104881035 T/C cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs7267979 1.000 rs6050561 chr20:25334855 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611519 0.780 rs5751072 chr22:41656509 C/T cg13695892 chr22:41940480 POLR3H -0.65 -6.22 -0.49 7.03e-9 Neuroticism; TGCT cis rs2075371 0.966 rs722657 chr7:133994956 T/C cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs10465746 0.935 rs6687372 chr1:84447634 C/T cg10977910 chr1:84465055 TTLL7 0.63 6.23 0.49 6.49e-9 Obesity-related traits; TGCT cis rs6988636 0.710 rs73339626 chr8:124142757 A/G cg23067535 chr8:124195133 FAM83A -0.38 -4.8 -0.4 4.53e-6 Urinary uromodulin levels; TGCT trans rs66573146 0.831 rs66645969 chr4:6985614 G/A cg07817883 chr1:32538562 TMEM39B 1.42 7.53 0.56 8.92e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs4819052 0.851 rs13050359 chr21:46672671 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs651907 0.557 rs2318090 chr3:101474933 A/G cg12386194 chr3:101231763 SENP7 0.49 4.69 0.39 7.17e-6 Colorectal cancer; TGCT cis rs2887571 0.505 rs34085684 chr12:1637686 C/T cg01940102 chr12:1095972 NA 0.26 4.78 0.39 4.92e-6 Bone mineral density; TGCT cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg13395646 chr4:1353034 KIAA1530 -0.4 -5.0 -0.41 1.93e-6 Obesity-related traits; TGCT cis rs904251 0.523 rs2797799 chr6:37483620 T/G cg08126542 chr6:37504118 NA -0.42 -6.17 -0.48 8.77e-9 Cognitive performance; TGCT cis rs6835098 0.500 rs13112928 chr4:174158132 A/G cg08422745 chr4:174089978 GALNT7 0.59 5.57 0.45 1.47e-7 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs954108 0.809 rs947248 chr13:29369553 G/T cg11788234 chr13:29393811 NA -0.37 -4.48 -0.37 1.68e-5 Obesity-related traits; TGCT cis rs60871478 0.588 rs56205589 chr7:910419 G/A cg00475322 chr7:917719 C7orf20 0.52 5.04 0.41 1.58e-6 Cerebrospinal P-tau181p levels; TGCT cis rs763121 0.776 rs4820346 chr22:39125074 C/G cg06022373 chr22:39101656 GTPBP1 -0.61 -5.61 -0.45 1.26e-7 Menopause (age at onset); TGCT cis rs651907 0.557 rs2318090 chr3:101474933 A/G cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.69 -0.51 7.01e-10 Colorectal cancer; TGCT cis rs35306767 0.761 rs11253557 chr10:1043667 C/T cg20503657 chr10:835505 NA 0.61 6.78 0.52 4.27e-10 Eosinophil percentage of granulocytes; TGCT cis rs7772486 0.777 rs1546966 chr6:146386018 G/T cg23711669 chr6:146136114 FBXO30 0.66 5.96 0.47 2.46e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs6833822 chr4:98951354 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9868809 0.505 rs11706203 chr3:48746239 T/A cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7542091 0.704 rs2142907 chr1:210039505 T/C cg21951975 chr1:209979733 IRF6 0.61 6.19 0.49 8.21e-9 Monobrow; TGCT cis rs9894429 0.966 rs6565604 chr17:79589242 G/A cg21028142 chr17:79581711 NPLOC4 0.29 6.83 0.52 3.44e-10 Eye color traits; TGCT cis rs2120019 1.000 rs60425110 chr15:75333000 T/A cg17294928 chr15:75287854 SCAMP5 -0.78 -6.12 -0.48 1.14e-8 Blood trace element (Zn levels); TGCT cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg04546413 chr19:29218101 NA 0.86 7.0 0.53 1.45e-10 Methadone dose in opioid dependence; TGCT cis rs10197940 0.710 rs4500942 chr2:152334580 A/G cg19508488 chr2:152266495 RIF1 0.7 6.53 0.51 1.49e-9 Lung cancer; TGCT cis rs7208859 0.673 rs9899943 chr17:29223925 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg24675658 chr1:53192096 ZYG11B -0.74 -8.18 -0.59 2.88e-13 Monocyte count; TGCT cis rs7945705 0.905 rs2568054 chr11:8876029 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -5.62 -0.45 1.21e-7 Hemoglobin concentration; TGCT cis rs10791097 0.694 rs3190331 chr11:130748131 C/T cg12179176 chr11:130786555 SNX19 -0.82 -10.0 -0.67 1.29e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7614311 0.636 rs17344090 chr3:64004101 T/C cg22134162 chr3:63841271 THOC7 -0.43 -5.53 -0.44 1.79e-7 Lung function (FVC);Lung function (FEV1); TGCT trans rs12038357 1.000 rs6664636 chr1:34966194 A/G cg06277588 chr6:13489246 GFOD1 0.54 7.06 0.54 1.02e-10 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs769267 0.896 rs7250893 chr19:19625547 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs806215 0.950 rs3735644 chr7:127222157 G/A cg25922125 chr7:127225783 GCC1 -0.61 -6.3 -0.49 4.71e-9 Type 2 diabetes; TGCT cis rs1008375 1.000 rs11737138 chr4:17657986 G/A cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1757171 0.542 rs1757186 chr6:37484111 A/G cg08126542 chr6:37504118 NA -0.44 -6.47 -0.5 2.04e-9 Cognitive performance; TGCT cis rs7845219 0.544 rs7015841 chr8:95920193 A/C cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs9467711 1.000 rs6939978 chr6:26328462 G/C cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs78456975 0.550 rs11904276 chr2:1524006 T/C cg01028140 chr2:1542097 TPO -0.33 -4.77 -0.39 5.01e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7959452 0.535 rs2305641 chr12:69646914 C/T cg14784868 chr12:69753453 YEATS4 0.69 7.13 0.54 7.26e-11 Blood protein levels; TGCT cis rs778371 0.958 rs2675968 chr2:233736244 A/G cg08000102 chr2:233561755 GIGYF2 0.59 6.56 0.51 1.29e-9 Schizophrenia; TGCT cis rs4808199 0.901 rs11669516 chr19:19532682 G/A cg03709012 chr19:19516395 GATAD2A 0.98 7.76 0.57 2.68e-12 Nonalcoholic fatty liver disease; TGCT cis rs12477438 0.520 rs2632283 chr2:99776000 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs1420338 0.967 rs10807873 chr7:34171276 C/T cg01275685 chr7:34179230 BMPER -0.26 -4.64 -0.38 8.75e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2204008 0.639 rs7311462 chr12:38278130 G/A cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs7246657 0.722 rs958305 chr19:38189440 A/G cg03611452 chr19:38183253 ZNF781 -0.66 -5.65 -0.45 1.02e-7 Coronary artery calcification; TGCT cis rs4665809 0.590 rs7606351 chr2:26292545 A/C cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs3806843 0.549 rs246012 chr5:140336277 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs17102423 0.623 rs2093989 chr14:65553939 C/T cg11161011 chr14:65562177 MAX -0.5 -6.94 -0.53 1.91e-10 Obesity-related traits; TGCT cis rs7572733 0.515 rs1836234 chr2:198882873 T/G cg00792783 chr2:198669748 PLCL1 0.59 5.34 0.43 4.33e-7 Dermatomyositis; TGCT cis rs7523273 0.925 rs10863593 chr1:208018074 C/T cg22525895 chr1:207977042 MIR29B2 0.54 6.5 0.5 1.77e-9 Schizophrenia; TGCT cis rs6678914 1.000 rs12028423 chr1:202187960 C/T cg08883485 chr1:201619787 NAV1 -0.39 -4.54 -0.38 1.3e-5 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs6831352 1.000 rs1126670 chr4:100052733 C/A cg12011299 chr4:100065546 ADH4 0.41 5.2 0.42 8.11e-7 Alcohol dependence; TGCT cis rs8017423 0.967 rs8009493 chr14:90690083 G/C cg04374321 chr14:90722782 PSMC1 0.77 8.02 0.58 6.73e-13 Mortality in heart failure; TGCT cis rs9381040 0.610 rs9394758 chr6:41017821 C/T cg03526776 chr6:41159608 TREML2 0.26 5.14 0.42 1.05e-6 Alzheimer's disease (late onset); TGCT cis rs6964587 0.605 rs6956022 chr7:91553199 A/G cg17063962 chr7:91808500 NA -0.76 -7.25 -0.55 3.94e-11 Breast cancer; TGCT cis rs7428 0.520 rs7605890 chr2:85559525 A/C cg24342717 chr2:85555507 TGOLN2 -0.49 -8.34 -0.6 1.23e-13 Ear protrusion; TGCT cis rs6671200 0.915 rs259334 chr1:95739701 C/T cg20701556 chr1:95698924 RWDD3 -0.69 -5.28 -0.43 5.53e-7 Stearic acid (18:0) levels; TGCT cis rs875971 0.830 rs12673450 chr7:66009220 G/A cg11764359 chr7:65958608 NA 0.58 5.31 0.43 4.88e-7 Aortic root size; TGCT cis rs2066819 1.000 rs79718165 chr12:56644251 C/T cg26714650 chr12:56694279 CS -1.33 -6.24 -0.49 6.46e-9 Psoriasis vulgaris; TGCT cis rs617219 0.726 rs1275105 chr5:78444148 T/C cg05890484 chr5:78407552 BHMT 0.36 4.94 0.41 2.47e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs829883 0.616 rs249832 chr12:98832387 C/T cg25150519 chr12:98850993 NA 0.62 7.36 0.55 2.2e-11 Colorectal adenoma (advanced); TGCT cis rs372883 0.600 rs2832295 chr21:30739843 C/T cg24692254 chr21:30365293 RNF160 0.51 4.6 0.38 1.02e-5 Pancreatic cancer; TGCT cis rs4319547 0.915 rs10734924 chr12:123018894 T/G cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.34 -0.43 4.19e-7 Body mass index; TGCT cis rs9914988 0.619 rs12451955 chr17:27314224 A/G cg16968985 chr17:27313254 SEZ6 -0.36 -4.5 -0.37 1.56e-5 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9381040 0.655 rs9381032 chr6:41044986 A/T cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs12950390 0.893 rs72831644 chr17:45824391 T/C cg06532163 chr17:45867833 NA 0.34 5.28 0.43 5.67e-7 IgG glycosylation; TGCT cis rs1577917 0.917 rs1414201 chr6:86500316 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs7772486 0.790 rs4314514 chr6:146260010 A/G cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs34734847 1.000 rs55730005 chr12:121157536 C/A cg21892295 chr12:121157589 UNC119B -0.24 -5.71 -0.46 7.99e-8 Mean corpuscular volume; TGCT trans rs62103177 0.564 rs11874805 chr18:77697110 T/C cg05926928 chr17:57297772 GDPD1 0.96 8.96 0.63 3.97e-15 Opioid sensitivity; TGCT cis rs4746818 0.711 rs2491024 chr10:70847084 T/C cg11621586 chr10:70884670 VPS26A 0.9 7.97 0.58 8.66e-13 Left atrial antero-posterior diameter; TGCT cis rs7582180 0.613 rs12988464 chr2:100946285 A/G cg14675211 chr2:100938903 LONRF2 0.47 4.57 0.38 1.16e-5 Intelligence (multi-trait analysis); TGCT cis rs2895526 0.715 rs7101243 chr10:12691273 C/G cg18283737 chr10:12085149 UPF2 -0.46 -4.54 -0.38 1.31e-5 Headache; TGCT cis rs10779751 0.734 rs2039840 chr1:11125866 G/A cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs10838634 1.000 rs56311746 chr11:46818043 A/T cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg10150615 chr22:24372951 LOC391322 -0.97 -12.67 -0.75 4.14e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9653442 0.510 rs12712068 chr2:100764439 A/G cg22139774 chr2:100720529 AFF3 -0.36 -5.69 -0.45 8.85e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2840044 1.000 rs9913003 chr17:33893904 C/A cg05299278 chr17:33885742 SLFN14 -0.23 -5.28 -0.43 5.7e-7 Response to radiotherapy in cancer (late toxicity); TGCT cis rs1783925 1.000 rs640364 chr11:125300766 G/A cg03464685 chr11:125439445 EI24 -0.55 -4.48 -0.37 1.67e-5 Formal thought disorder in schizophrenia; TGCT cis rs2115630 1.000 rs2879828 chr15:85361977 G/T cg12501888 chr15:85177176 SCAND2 -0.49 -4.56 -0.38 1.22e-5 P wave terminal force; TGCT cis rs35306767 0.903 rs11253504 chr10:956046 A/G cg26597838 chr10:835615 NA 0.75 10.39 0.68 1.43e-18 Eosinophil percentage of granulocytes; TGCT cis rs9611565 0.694 rs5758411 chr22:42079734 G/A cg06634786 chr22:41940651 POLR3H 0.82 7.82 0.57 1.92e-12 Vitiligo; TGCT cis rs907683 0.584 rs12621188 chr2:220287892 C/G cg15015639 chr2:220282977 DES 0.4 5.11 0.42 1.18e-6 Resting heart rate; TGCT cis rs2797160 0.967 rs1954360 chr6:126001064 A/G cg05901451 chr6:126070800 HEY2 -0.75 -6.51 -0.5 1.69e-9 Endometrial cancer; TGCT cis rs763121 0.651 rs738249 chr22:39037979 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs7726839 0.540 rs4957080 chr5:644552 A/C cg16624210 chr5:671434 TPPP -0.4 -4.52 -0.38 1.44e-5 Obesity-related traits; TGCT cis rs6089829 0.962 rs57684920 chr20:61662639 G/A cg08564027 chr20:61660810 NA -0.36 -6.44 -0.5 2.42e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg22166914 chr1:53195759 ZYG11B 0.37 5.98 0.47 2.27e-8 Monocyte count; TGCT cis rs904251 0.861 rs2776875 chr6:37486796 G/C cg25019722 chr6:37503610 NA -0.5 -6.92 -0.53 2.17e-10 Cognitive performance; TGCT trans rs7618501 0.735 rs9876508 chr3:49780844 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs9372498 0.536 rs9489467 chr6:118935206 C/T cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs514406 0.584 rs7548832 chr1:53193576 A/T cg22166914 chr1:53195759 ZYG11B 0.5 9.39 0.64 3.72e-16 Monocyte count; TGCT cis rs9650657 0.644 rs3808603 chr8:10698218 T/C cg16664915 chr8:10907788 XKR6 -0.28 -4.54 -0.38 1.3e-5 Neuroticism; TGCT cis rs11031096 0.563 rs12281849 chr11:4224832 C/T cg18678763 chr11:4115507 RRM1 -0.39 -4.91 -0.4 2.82e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1056107 0.931 rs7048773 chr9:114988668 C/T cg02332936 chr9:115140584 NA -0.27 -4.7 -0.39 6.68e-6 Colorectal cancer; TGCT cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7524258 0.903 rs4908449 chr1:7292700 T/C cg07173049 chr1:7289937 CAMTA1 0.32 5.31 0.43 4.88e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs17152411 0.895 rs7080475 chr10:126585767 A/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs7772486 0.624 rs6930154 chr6:146025662 C/T cg23711669 chr6:146136114 FBXO30 -0.92 -10.55 -0.69 5.88e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs4242434 0.646 rs6988593 chr8:22527440 A/G cg21658235 chr8:22456391 C8orf58 -0.44 -4.76 -0.39 5.24e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9325144 0.600 rs7965877 chr12:38743697 G/T cg26384229 chr12:38710491 ALG10B 0.61 5.61 0.45 1.28e-7 Morning vs. evening chronotype; TGCT cis rs2075371 1.000 rs2598297 chr7:133993001 T/G cg11752832 chr7:134001865 SLC35B4 0.69 6.26 0.49 5.87e-9 Mean platelet volume; TGCT cis rs853679 0.546 rs200996 chr6:27811828 G/A cg08798685 chr6:27730294 NA -0.34 -4.77 -0.39 5.13e-6 Depression; TGCT cis rs2204008 0.720 rs11181343 chr12:38323616 G/T cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.76e-11 Bladder cancer; TGCT cis rs116095464 0.558 rs10058428 chr5:235608 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs597539 0.580 rs7935851 chr11:68731122 A/G cg04772025 chr11:68637568 NA 0.61 6.75 0.52 4.94e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs597539 0.616 rs473997 chr11:68639481 C/T cg04772025 chr11:68637568 NA 0.6 6.78 0.52 4.32e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28595532 0.765 rs114082534 chr4:119734184 G/A cg14228332 chr4:119757509 SEC24D 1.32 5.99 0.47 2.14e-8 Cannabis dependence symptom count; TGCT cis rs3733585 0.753 rs1122141 chr4:9947278 T/C cg11266682 chr4:10021025 SLC2A9 -0.63 -8.66 -0.61 2.16e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1018836 0.923 rs13259842 chr8:91550819 A/G cg16814680 chr8:91681699 NA -0.88 -9.81 -0.66 3.71e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9952991 0.941 rs34920518 chr18:12783086 A/G cg23544223 chr18:12777786 NA -0.6 -5.51 -0.44 1.99e-7 Inflammatory skin disease; TGCT cis rs651907 0.535 rs1460097 chr3:101497569 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.47 0.68 9.24e-19 Colorectal cancer; TGCT cis rs9993613 0.841 rs16848467 chr4:73529442 A/C cg15102770 chr4:73434591 ADAMTS3 0.5 4.57 0.38 1.18e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs244731 1.000 rs244730 chr5:176539212 A/G cg06060754 chr5:176797920 RGS14 -0.39 -5.52 -0.44 1.86e-7 Urate levels in lean individuals; TGCT cis rs1008375 1.000 rs56974987 chr4:17627856 G/A cg16339924 chr4:17578868 LAP3 0.62 5.11 0.42 1.17e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9399137 0.507 rs6904897 chr6:135382980 T/G cg24558204 chr6:135376177 HBS1L 0.47 4.73 0.39 5.98e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs3008870 0.727 rs2755270 chr1:67474503 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.81 8.43 0.6 7.53e-14 Lymphocyte percentage of white cells; TGCT cis rs7769051 1.000 rs9493443 chr6:133121349 C/T cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg06481639 chr22:41940642 POLR3H 0.74 6.35 0.5 3.62e-9 Vitiligo; TGCT cis rs453301 0.686 rs10217044 chr8:8894752 A/G cg06636001 chr8:8085503 FLJ10661 -0.66 -5.57 -0.45 1.49e-7 Joint mobility (Beighton score); TGCT cis rs425277 1.000 rs262670 chr1:2082458 C/T cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs910187 0.605 rs6018317 chr20:45803236 A/G cg27589058 chr20:45804311 EYA2 -0.4 -8.92 -0.63 5.1e-15 Migraine; TGCT cis rs10510102 0.872 rs11200293 chr10:123728710 C/T cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs1044826 0.642 rs432387 chr3:139231853 T/G cg00490450 chr3:139108681 COPB2 -0.51 -4.48 -0.37 1.67e-5 Obesity-related traits; TGCT cis rs4819052 0.851 rs2838842 chr21:46669217 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.04 0.41 1.63e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2180341 0.782 rs6912196 chr6:127722732 C/G cg24812749 chr6:127587940 RNF146 0.65 5.19 0.42 8.37e-7 Breast cancer; TGCT cis rs28595532 0.841 rs114123875 chr4:119733408 A/G cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7412746 0.658 rs4970982 chr1:150865084 G/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs11718455 0.883 rs6795366 chr3:44005735 C/T cg08738300 chr3:44038990 NA 0.84 6.27 0.49 5.39e-9 Coronary artery disease; TGCT cis rs736408 0.505 rs2083180 chr3:52668119 G/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.71 -0.39 6.66e-6 Bipolar disorder; TGCT cis rs68170813 0.641 rs75639044 chr7:107092631 A/C cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs12118280 0.921 rs61799378 chr1:108742130 T/C cg11967332 chr1:108735228 SLC25A24 0.39 5.44 0.44 2.74e-7 Myeloid white cell count; TGCT cis rs9303542 0.694 rs4793854 chr17:46572133 A/G cg25032089 chr17:46643351 HOXB3 -0.52 -5.88 -0.47 3.51e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs11025559 0.796 rs11603462 chr11:20412180 C/A cg19653624 chr11:20408972 PRMT3 -0.64 -5.07 -0.41 1.43e-6 Pursuit maintenance gain; TGCT cis rs6582630 0.560 rs12315134 chr12:38419857 T/A cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1215050 0.791 rs7434393 chr4:98768576 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs3096299 0.632 rs8051537 chr16:89544384 T/A cg02187348 chr16:89574699 SPG7 0.61 6.67 0.51 7.56e-10 Multiple myeloma (IgH translocation); TGCT cis rs9393777 0.778 rs35608615 chr6:27040402 G/C cg16898833 chr6:26189333 HIST1H4D 1.0 5.74 0.46 6.81e-8 Intelligence (multi-trait analysis); TGCT trans rs7618501 0.633 rs4688757 chr3:50035323 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.92 0.67 1.95e-17 Intelligence (multi-trait analysis); TGCT trans rs916888 0.779 rs199528 chr17:44843136 C/T cg22433210 chr17:43662623 NA 0.99 7.14 0.54 7.1e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10031466 0.967 rs12647135 chr4:189011174 A/C cg14506195 chr4:188913931 NA 0.27 5.11 0.42 1.18e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs250677 1.000 rs36079 chr5:148430504 G/A cg18129178 chr5:148520854 ABLIM3 -0.42 -6.46 -0.5 2.15e-9 Breast cancer; TGCT cis rs9807841 0.643 rs4435370 chr19:10774623 G/A cg17848348 chr19:10766748 ILF3 -0.4 -4.58 -0.38 1.12e-5 Inflammatory skin disease; TGCT cis rs7474896 0.583 rs4934898 chr10:37990395 G/C cg25427524 chr10:38739819 LOC399744 -0.3 -4.53 -0.38 1.36e-5 Obesity (extreme); TGCT cis rs2153535 0.542 rs6912740 chr6:8439959 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs7829975 0.623 rs10087493 chr8:8373557 A/G cg15556689 chr8:8085844 FLJ10661 -0.73 -7.14 -0.54 6.83e-11 Mood instability; TGCT cis rs921968 0.643 rs520095 chr2:219329485 C/T cg02176678 chr2:219576539 TTLL4 0.37 5.45 0.44 2.58e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs2439831 0.850 rs3097773 chr15:43893072 A/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.8 -5.17 -0.42 8.98e-7 Lung cancer in ever smokers; TGCT cis rs35146811 0.735 rs1636975 chr7:99812089 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs17443541 0.507 rs13020883 chr2:200447031 C/A cg00055341 chr2:200446845 NA 0.38 4.6 0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs9972944 0.756 rs6504343 chr17:63755458 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.07 -0.41 1.39e-6 Total body bone mineral density; TGCT cis rs2882877 0.648 rs11680808 chr2:190376493 A/G cg10752008 chr2:190445175 SLC40A1 0.61 4.48 0.37 1.68e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs2880765 0.835 rs4344688 chr15:86043007 A/C cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs939574 0.790 rs72955447 chr2:220098287 G/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.04 4.8 0.4 4.54e-6 Platelet distribution width; TGCT cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg17345569 chr6:42928274 GNMT -0.47 -4.85 -0.4 3.69e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12681288 0.862 rs2600493 chr8:1024970 A/G cg08872321 chr8:1308229 NA -0.25 -4.64 -0.38 8.71e-6 Schizophrenia; TGCT cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg08859206 chr1:53392774 SCP2 0.47 7.42 0.55 1.58e-11 Monocyte count; TGCT cis rs6754311 0.731 rs13404551 chr2:136721995 T/C cg07169764 chr2:136633963 MCM6 0.63 5.88 0.47 3.57e-8 Mosquito bite size; TGCT cis rs2948294 0.524 rs13270062 chr8:8112650 C/A cg15462221 chr8:8086144 FLJ10661 -0.6 -5.1 -0.42 1.23e-6 Red cell distribution width; TGCT cis rs6582630 0.593 rs7134006 chr12:38596245 A/C cg13010199 chr12:38710504 ALG10B 0.65 5.07 0.41 1.41e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs13256369 0.851 rs12541477 chr8:8563895 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs3741404 0.825 rs7111753 chr11:63942189 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.89 9.88 0.66 2.53e-17 Platelet count; TGCT cis rs7208859 0.573 rs8064686 chr17:29134839 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2456568 0.933 rs1518577 chr11:93674907 C/T cg17595323 chr11:93583763 C11orf90 -0.46 -5.86 -0.47 3.92e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7714584 1.000 rs7732945 chr5:150261601 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs910316 1.000 rs7156105 chr14:75541954 C/A cg08847533 chr14:75593920 NEK9 0.97 10.82 0.7 1.3e-19 Height; TGCT cis rs11123694 1.000 rs11123694 chr2:109064563 C/T cg02082929 chr2:109068933 GCC2 0.26 6.34 0.49 3.96e-9 Mean platelet volume; TGCT cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.841 rs114363775 chr4:119765587 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs9300255 0.569 rs1716170 chr12:123716513 C/T cg00376283 chr12:123451042 ABCB9 0.67 5.26 0.43 6.13e-7 Neutrophil percentage of white cells; TGCT cis rs7772486 0.558 rs62435775 chr6:146136415 G/C cg05347473 chr6:146136440 FBXO30 0.66 6.2 0.49 7.78e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6558174 0.714 rs12541601 chr8:22524141 G/A cg03733263 chr8:22462867 KIAA1967 -0.61 -4.76 -0.39 5.19e-6 Breast cancer; TGCT cis rs7572733 0.534 rs700683 chr2:198712332 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Vitiligo; TGCT cis rs826838 0.620 rs11614695 chr12:39331847 C/T cg13010199 chr12:38710504 ALG10B 0.64 4.91 0.4 2.79e-6 Heart rate; TGCT cis rs9926296 0.605 rs6500449 chr16:89856393 T/C cg04287289 chr16:89883240 FANCA 0.93 11.83 0.73 4.42e-22 Vitiligo; TGCT cis rs2721195 0.577 rs4532636 chr8:145904423 A/C cg11211951 chr8:145729740 GPT -0.23 -4.97 -0.41 2.14e-6 Age at first birth; TGCT cis rs875971 0.929 rs778692 chr7:65872449 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs4851254 0.660 rs9784000 chr2:100697201 G/C cg07810366 chr2:100720526 AFF3 -0.45 -4.7 -0.39 6.91e-6 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.932 rs11938710 chr4:17670664 G/C cg18681998 chr4:17616180 MED28 -0.87 -8.78 -0.62 1.07e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.660 rs10263935 chr7:66096028 A/G cg18876405 chr7:65276391 NA 0.34 5.28 0.43 5.69e-7 Aortic root size; TGCT cis rs9381040 0.610 rs4140580 chr6:41041742 C/T cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs7666738 0.830 rs1834647 chr4:98882915 G/A cg05340658 chr4:99064831 C4orf37 0.53 6.1 0.48 1.22e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9388451 0.626 rs7748729 chr6:126077381 C/T cg05901451 chr6:126070800 HEY2 -0.98 -12.15 -0.74 7.57e-23 Brugada syndrome; TGCT cis rs9911578 0.692 rs412000 chr17:56709058 G/C cg12560992 chr17:57184187 TRIM37 0.55 5.96 0.47 2.38e-8 Intelligence (multi-trait analysis); TGCT cis rs11190604 0.767 rs10509743 chr10:102190406 C/T cg16005271 chr10:102321736 NA 0.46 4.67 0.39 7.62e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3125734 0.719 rs4529854 chr10:64043975 C/T cg09941381 chr10:64027924 RTKN2 -0.31 -4.5 -0.37 1.55e-5 Rheumatoid arthritis; TGCT cis rs9300255 0.510 rs1727322 chr12:123699520 A/G cg00376283 chr12:123451042 ABCB9 0.73 5.1 0.42 1.26e-6 Neutrophil percentage of white cells; TGCT cis rs6570726 0.764 rs9403733 chr6:145912311 A/C cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11031096 0.587 rs2920145 chr11:4070552 G/T cg18678763 chr11:4115507 RRM1 0.36 4.56 0.38 1.2e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7568458 0.704 rs10176176 chr2:85762048 A/T cg02493740 chr2:85810744 VAMP5 -0.28 -5.23 -0.42 7.12e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10782582 0.593 rs6675212 chr1:76230829 C/A cg10523679 chr1:76189770 ACADM -0.61 -6.16 -0.48 9.21e-9 Daytime sleep phenotypes; TGCT cis rs6840360 0.571 rs55808836 chr4:152554991 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs4523957 0.620 rs9900587 chr17:2071097 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.46 -0.37 1.8e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2456568 0.695 rs7942055 chr11:93691063 A/C cg26875233 chr11:93583750 C11orf90 0.4 4.79 0.4 4.6e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs447921 0.861 rs12950218 chr17:74409547 G/A cg09812376 chr17:74270190 QRICH2 -0.46 -4.6 -0.38 1.01e-5 Mitochondrial DNA levels; TGCT cis rs35306767 0.807 rs34982663 chr10:852521 C/G cg20503657 chr10:835505 NA 0.77 11.14 0.71 2.13e-20 Eosinophil percentage of granulocytes; TGCT cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs12369635 1.000 rs73159540 chr12:129559421 C/T cg01909103 chr12:129572610 TMEM132D -0.64 -4.47 -0.37 1.73e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs826838 0.904 rs7973992 chr12:39168233 T/C cg13010199 chr12:38710504 ALG10B 0.78 6.16 0.48 9.26e-9 Heart rate; TGCT cis rs595982 0.527 rs17272673 chr19:49362992 C/A cg17863274 chr19:49399704 TULP2 -0.47 -6.71 -0.52 6.17e-10 Red cell distribution width; TGCT cis rs3821902 0.646 rs66672237 chr3:64012172 C/A cg22134162 chr3:63841271 THOC7 -0.33 -4.96 -0.41 2.22e-6 Breast cancer; TGCT cis rs6430585 0.528 rs114760827 chr2:136661110 G/A cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs17376456 0.569 rs7732578 chr5:93410244 C/T cg21475434 chr5:93447410 FAM172A -0.61 -5.8 -0.46 5.24e-8 Diabetic retinopathy; TGCT cis rs6430585 0.528 rs309120 chr2:136708787 G/C cg07169764 chr2:136633963 MCM6 1.21 11.87 0.73 3.62e-22 Corneal structure; TGCT cis rs2404602 0.735 rs2461871 chr15:76822418 C/G cg06069100 chr15:77574588 SGK269 0.26 4.67 0.39 7.65e-6 Blood metabolite levels; TGCT cis rs6546537 0.550 rs12617329 chr2:69781530 C/A cg10773587 chr2:69614142 GFPT1 -0.65 -5.94 -0.47 2.7e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs2153535 0.580 rs915351 chr6:8442793 C/T cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs708547 0.836 rs1713997 chr4:57843863 G/C cg25525207 chr4:57843836 C4orf14;POLR2B -0.54 -5.11 -0.42 1.16e-6 Response to bleomycin (chromatid breaks); TGCT cis rs5750830 0.649 rs6001588 chr22:39819049 G/C cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.559 rs7850228 chr9:5210671 C/G cg02405213 chr9:5042618 JAK2 0.67 8.47 0.61 5.81e-14 Pediatric autoimmune diseases; TGCT trans rs1005277 0.563 rs2505215 chr10:38481273 A/G cg17830980 chr10:43048298 ZNF37B -0.84 -10.46 -0.68 9.38e-19 Extrinsic epigenetic age acceleration; TGCT cis rs9467773 1.000 rs4713006 chr6:26519872 A/G cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs17102423 0.723 rs8181937 chr14:65555707 A/C cg11161011 chr14:65562177 MAX -0.55 -7.67 -0.57 4.42e-12 Obesity-related traits; TGCT cis rs1784581 0.569 rs9364629 chr6:162416831 T/G cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.07e-9 Itch intensity from mosquito bite; TGCT cis rs2404602 0.647 rs12905181 chr15:77098431 A/G cg23625390 chr15:77176239 SCAPER -0.38 -4.77 -0.39 5.13e-6 Blood metabolite levels; TGCT cis rs9814567 1.000 rs7630874 chr3:134293291 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10791097 0.702 rs10894267 chr11:130714861 C/T cg05962950 chr11:130786565 SNX19 -0.7 -7.38 -0.55 1.97e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11112613 0.713 rs12580741 chr12:105941328 A/G cg03607813 chr12:105948248 NA -0.41 -4.66 -0.39 7.91e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs57590327 0.528 rs3821552 chr3:81702139 A/G cg07356753 chr3:81810745 GBE1 -0.77 -6.91 -0.53 2.24e-10 Extraversion; TGCT cis rs2463822 0.514 rs10750972 chr11:62053687 A/G cg23876832 chr11:62092739 NA 0.69 5.9 0.47 3.17e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs610932 0.517 rs612738 chr11:59990591 G/T cg18570331 chr11:60101691 MS4A6E 0.51 4.64 0.38 8.88e-6 Alzheimer's disease; TGCT cis rs9296092 0.538 rs9461887 chr6:33526827 C/T cg13560919 chr6:33536144 NA -0.22 -4.95 -0.41 2.33e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7027203 0.576 rs7865043 chr9:96549004 G/T cg14396892 chr9:96623032 NA 0.22 4.5 0.37 1.54e-5 DNA methylation (variation); TGCT cis rs12368653 0.525 rs1564374 chr12:58010163 C/T cg12615879 chr12:58013172 SLC26A10 0.54 6.5 0.5 1.77e-9 Multiple sclerosis; TGCT cis rs6665290 0.836 rs56029302 chr1:227203390 G/A cg11404489 chr1:228071452 NA -0.19 -4.6 -0.38 1.02e-5 Myeloid white cell count; TGCT cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg26531700 chr6:26746687 NA 0.5 4.62 0.38 9.55e-6 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.838 rs2243834 chr2:26357748 A/C cg22920501 chr2:26401640 FAM59B 0.66 6.24 0.49 6.48e-9 Gut microbiome composition (summer); TGCT cis rs8009147 1 rs8009147 chr14:104264662 A/G cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs17331151 0.573 rs11718060 chr3:52875546 G/A cg12962167 chr3:53033115 SFMBT1 0.43 4.71 0.39 6.6e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg22907277 chr7:1156413 C7orf50 0.21 4.8 0.4 4.48e-6 Longevity;Endometriosis; TGCT cis rs6570726 0.791 rs13202312 chr6:145913093 T/G cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2204008 0.624 rs2320449 chr12:38224190 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.34 0.55 2.44e-11 Bladder cancer; TGCT cis rs763014 0.898 rs1981484 chr16:630710 A/G cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs2180341 0.751 rs9388553 chr6:127574044 A/G cg27446573 chr6:127587934 RNF146 0.98 8.94 0.63 4.63e-15 Breast cancer; TGCT cis rs6121246 0.609 rs6060627 chr20:30262159 C/T cg18721089 chr20:30220636 NA -0.35 -4.49 -0.37 1.6e-5 Mean corpuscular hemoglobin; TGCT cis rs2243480 1.000 rs316304 chr7:65616894 T/C cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs7027203 0.538 rs10125195 chr9:96523224 T/C cg14598338 chr9:96623480 NA -0.49 -7.04 -0.53 1.18e-10 DNA methylation (variation); TGCT cis rs801193 1.000 rs7789184 chr7:66210195 A/T cg00343986 chr7:65444356 GUSB 0.24 5.25 0.43 6.3e-7 Aortic root size; TGCT trans rs6762477 0.748 rs11717349 chr3:50223977 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.78 -8.11 -0.59 4.24e-13 Menarche (age at onset); TGCT cis rs12478296 0.901 rs67423532 chr2:243004719 A/G cg06360820 chr2:242988706 NA -0.64 -5.35 -0.43 4.15e-7 Obesity-related traits; TGCT cis rs9486719 1.000 rs2971608 chr6:97039757 T/C cg06623918 chr6:96969491 KIAA0776 -1.04 -10.25 -0.68 3.11e-18 Migraine;Coronary artery disease; TGCT cis rs10411936 0.888 rs2034892 chr19:16491549 G/A cg19006008 chr19:16999768 F2RL3 0.26 4.58 0.38 1.13e-5 White blood cell count;Multiple sclerosis; TGCT cis rs9926296 0.593 rs6500456 chr16:89888341 T/C cg08627397 chr16:89984028 MC1R -0.31 -4.92 -0.4 2.67e-6 Vitiligo; TGCT trans rs629535 0.547 rs72654095 chr8:70120770 A/G cg21567404 chr3:27674614 NA -0.52 -8.05 -0.59 5.78e-13 Dupuytren's disease; TGCT cis rs75686122 0.892 rs17233499 chr8:104610414 C/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT trans rs1814175 0.817 rs11518158 chr11:49985633 G/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.59e-14 Height; TGCT cis rs10465746 0.935 rs4907189 chr1:84374982 G/T cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg22764044 chr5:178986830 RUFY1 0.47 5.27 0.43 5.74e-7 Lung cancer; TGCT cis rs7914558 1.000 rs11191577 chr10:104902165 A/G cg15744005 chr10:104629667 AS3MT -0.42 -5.24 -0.43 6.69e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs548987 0.529 rs651578 chr6:25873883 T/C cg12310025 chr6:25882481 NA -0.66 -5.62 -0.45 1.22e-7 Homocysteine levels; TGCT cis rs651907 0.557 rs2318090 chr3:101474933 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.9 10.87 0.7 9.43e-20 Colorectal cancer; TGCT cis rs858239 0.600 rs10256359 chr7:23123877 C/T cg05602783 chr7:23145260 KLHL7 -0.6 -4.98 -0.41 2.11e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4803468 1.000 rs13344563 chr19:41945904 G/C cg09537434 chr19:41945824 ATP5SL 0.92 10.44 0.68 1.1e-18 Height; TGCT cis rs7822232 0.908 rs4977164 chr8:145144912 T/G cg26272248 chr8:145163034 KIAA1875 -0.49 -4.81 -0.4 4.24e-6 Blood metabolite levels; TGCT cis rs3026101 0.671 rs739767 chr17:5290681 A/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.57 0.38 1.16e-5 Body mass index; TGCT cis rs78487399 0.634 rs6751035 chr2:43752407 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.45 -5.11 -0.42 1.18e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7635838 0.617 rs13071193 chr3:11284226 G/T cg00170343 chr3:11313890 ATG7 -0.64 -6.28 -0.49 5.27e-9 HDL cholesterol; TGCT cis rs7618915 0.798 rs353547 chr3:52268866 A/G cg10802521 chr3:52805072 NEK4 0.47 4.93 0.41 2.53e-6 Bipolar disorder; TGCT cis rs8020441 0.945 rs61410944 chr14:51166736 A/G cg04730355 chr14:51134070 SAV1 0.71 5.77 0.46 5.92e-8 Cognitive performance; TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg03407747 chr17:6899364 ALOX12 0.54 5.85 0.47 4.06e-8 Tonsillectomy; TGCT trans rs57221529 0.766 rs72703042 chr5:579269 C/T cg11887960 chr12:57824829 NA 1.1 9.44 0.65 2.89e-16 Lung disease severity in cystic fibrosis; TGCT cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg09436375 chr6:42928200 GNMT -0.35 -4.54 -0.38 1.33e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg26354017 chr1:205819088 PM20D1 0.56 6.86 0.52 2.9e-10 Menarche (age at onset); TGCT cis rs78487399 0.731 rs6747229 chr2:43712610 T/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.71 4.55 0.38 1.26e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs908922 0.676 rs4845788 chr1:152519496 T/C cg20991723 chr1:152506922 NA 0.44 5.78 0.46 5.77e-8 Hair morphology; TGCT cis rs62380364 0.558 rs34319 chr5:88023349 A/T cg24804195 chr5:87968844 LOC645323 -0.59 -5.87 -0.47 3.67e-8 Intelligence (multi-trait analysis); TGCT cis rs4455778 0.580 rs4543492 chr7:49097005 C/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs2067615 0.599 rs1579808 chr12:107239947 A/G cg15890332 chr12:107067104 RFX4 -0.28 -5.54 -0.45 1.72e-7 Heart rate; TGCT cis rs77741769 0.571 rs989986 chr12:121274178 A/C cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.58e-5 Mean corpuscular volume; TGCT cis rs59197085 0.636 rs2307036 chr7:128454537 C/A cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs7666738 0.830 rs10017557 chr4:98983969 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs5769765 0.862 rs9616381 chr22:50312382 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs45509595 0.841 rs401754 chr6:27782538 T/A cg10876282 chr6:28092338 ZSCAN16 0.78 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs7769051 1.000 rs10484629 chr6:133117870 A/C cg22852734 chr6:133119734 C6orf192 1.22 6.9 0.53 2.34e-10 Type 2 diabetes nephropathy; TGCT cis rs4700695 0.719 rs27082 chr5:65436152 A/C cg21114390 chr5:65439923 SFRS12 -0.82 -7.51 -0.56 9.94e-12 Facial morphology (factor 19); TGCT cis rs6074578 0.679 rs6086226 chr20:137310 C/A cg16931068 chr20:139680 DEFB127 0.27 4.8 0.4 4.52e-6 Hirschsprung disease; TGCT cis rs9926296 0.682 rs645019 chr16:89716883 C/T cg27121462 chr16:89883253 FANCA -0.53 -4.88 -0.4 3.22e-6 Vitiligo; TGCT cis rs422249 0.512 rs174566 chr11:61592362 A/G cg19610905 chr11:61596333 FADS2 -1.08 -12.29 -0.74 3.45e-23 Trans fatty acid levels; TGCT cis rs2797160 1.000 rs6904069 chr6:125995134 C/T cg05901451 chr6:126070800 HEY2 -0.74 -6.68 -0.51 7.16e-10 Endometrial cancer; TGCT cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT trans rs8073060 0.544 rs7210966 chr17:33986334 G/C cg19694781 chr19:47549865 TMEM160 -0.62 -14.07 -0.78 1.86e-27 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2486288 0.656 rs7167146 chr15:45571386 A/G cg14582100 chr15:45693742 SPATA5L1 0.45 5.37 0.43 3.72e-7 Glomerular filtration rate; TGCT cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs12477438 0.501 rs2516833 chr2:99777405 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg07424592 chr7:64974309 NA 1.36 8.08 0.59 4.97e-13 Diabetic kidney disease; TGCT cis rs2652822 0.509 rs4774478 chr15:63434763 A/G cg12855773 chr15:63363890 TPM1 -0.2 -5.3 -0.43 5.04e-7 Metabolic traits; TGCT cis rs8014204 0.604 rs2159906 chr14:75390912 G/T cg06637938 chr14:75390232 RPS6KL1 0.96 10.93 0.7 6.98e-20 Caffeine consumption; TGCT cis rs11031096 0.711 rs4910890 chr11:4153407 C/T cg18678763 chr11:4115507 RRM1 -0.52 -6.66 -0.51 7.83e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6988636 1.000 rs4377946 chr8:124185887 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs78487399 0.634 rs77881454 chr2:43757293 A/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.75 4.63 0.38 9.1e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6089584 1.000 rs6089585 chr20:60564395 G/A cg16423285 chr20:60520624 NA -0.52 -5.62 -0.45 1.18e-7 Body mass index; TGCT cis rs9549367 0.569 rs3024738 chr13:113819921 T/A cg00898013 chr13:113819073 PROZ 0.5 6.19 0.49 8.12e-9 Platelet distribution width; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg04234412 chr22:24373322 LOC391322 0.96 10.26 0.68 2.96e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg13395646 chr4:1353034 KIAA1530 -0.4 -5.0 -0.41 1.93e-6 Obesity-related traits; TGCT cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg09436375 chr6:42928200 GNMT -0.38 -4.88 -0.4 3.2e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs11785400 1.000 rs3824208 chr8:143743653 C/G cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs7772486 0.790 rs2253880 chr6:146200774 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.88 0.4 3.15e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2549003 1.000 rs7701588 chr5:131819970 T/C cg02551604 chr5:131831745 NA -0.89 -11.95 -0.73 2.33e-22 Asthma (sex interaction); TGCT cis rs72949976 0.864 rs62186566 chr2:214024421 G/A cg08319019 chr2:214017104 IKZF2 -0.8 -7.47 -0.56 1.22e-11 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs13064447 0.817 rs73022939 chr3:12762264 G/A cg20675869 chr3:12750130 NA -0.2 -4.99 -0.41 2.03e-6 Major depression and alcohol dependence; TGCT cis rs8103278 0.507 rs62111759 chr19:46296230 A/T cg11657440 chr19:46296263 DMWD 0.79 8.7 0.62 1.7e-14 Coronary artery disease; TGCT cis rs2663905 0.611 rs1509558 chr15:81391244 C/T cg09236163 chr15:81426669 C15orf26 -0.46 -4.63 -0.38 9.26e-6 QT interval (drug interaction); TGCT cis rs12497850 0.543 rs6446218 chr3:49075513 A/T cg07636037 chr3:49044803 WDR6 0.98 10.81 0.7 1.33e-19 Parkinson's disease; TGCT cis rs11098499 0.909 rs28581362 chr4:120283548 T/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs11514810 1.000 rs4385385 chr7:1431125 T/C cg24899294 chr7:1481343 MICALL2 -0.47 -5.84 -0.46 4.24e-8 Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder; TGCT cis rs17253792 0.731 rs79483151 chr14:56048851 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs13108904 0.846 rs12643212 chr4:1224948 A/G cg05665937 chr4:1216051 CTBP1 0.23 4.58 0.38 1.13e-5 Obesity-related traits; TGCT cis rs2191566 0.664 rs6509138 chr19:44570393 C/A cg03039196 chr19:44506973 ZNF230 0.53 4.46 0.37 1.82e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs6933660 0.800 rs9383893 chr6:151757327 T/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.94 -10.66 -0.69 3.07e-19 Menarche (age at onset); TGCT trans rs11088226 0.681 rs1134747 chr21:33939011 T/A cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT cis rs72949976 0.584 rs12471471 chr2:214023052 C/T cg08319019 chr2:214017104 IKZF2 -0.84 -8.38 -0.6 9.58e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs4919694 1.000 rs12268849 chr10:104737682 G/A cg04362960 chr10:104952993 NT5C2 1.04 6.92 0.53 2.1e-10 Arsenic metabolism; TGCT cis rs7829975 0.871 rs777709 chr8:8583872 T/C cg08975724 chr8:8085496 FLJ10661 -0.52 -4.53 -0.38 1.39e-5 Mood instability; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs533581 0.866 rs488251 chr16:88972554 G/A cg16701003 chr16:89028210 CBFA2T3 0.38 4.86 0.4 3.45e-6 Social autistic-like traits; TGCT cis rs4664308 0.905 rs62175518 chr2:160915149 C/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.55 -0.51 1.36e-9 Idiopathic membranous nephropathy; TGCT cis rs1609391 0.561 rs6439675 chr3:136625436 G/A cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs739496 0.579 rs10849983 chr12:112340409 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs394563 0.591 rs237029 chr6:149717425 A/G cg03678062 chr6:149772716 ZC3H12D -0.38 -4.74 -0.39 5.87e-6 Dupuytren's disease; TGCT cis rs3617 0.625 rs2245647 chr3:52862753 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.59 0.38 1.08e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2404602 0.692 rs2117369 chr15:76748861 A/T cg22467129 chr15:76604101 ETFA -0.57 -6.83 -0.52 3.31e-10 Blood metabolite levels; TGCT cis rs11626933 1.000 rs11626933 chr14:90754311 A/G cg14092571 chr14:90743983 NA -0.29 -6.02 -0.48 1.86e-8 Gut microbiota (bacterial taxa); TGCT trans rs9951602 0.512 rs4799247 chr18:76653449 G/A cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs7246657 0.678 rs4802024 chr19:38052193 T/C cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs8072100 0.701 rs10163469 chr17:45687767 G/A cg08085267 chr17:45401833 C17orf57 0.43 4.63 0.38 9.02e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs473651 0.935 rs10170056 chr2:239339291 G/C cg08773314 chr2:239334832 ASB1 0.45 6.39 0.5 3.05e-9 Multiple system atrophy; TGCT cis rs7824557 0.545 rs2572380 chr8:11237477 A/G cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs9394438 0.628 rs804843 chr6:37545923 A/G cg00985040 chr6:37553208 NA -0.25 -4.94 -0.41 2.51e-6 IgG glycosylation; TGCT cis rs10782582 0.593 rs12129523 chr1:76129223 C/A cg03433033 chr1:76189801 ACADM -0.63 -7.25 -0.55 3.83e-11 Daytime sleep phenotypes; TGCT cis rs7264396 0.635 rs6060696 chr20:34522060 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs1023500 0.573 rs133381 chr22:42470608 C/G cg15557168 chr22:42548783 NA -0.22 -5.42 -0.44 2.99e-7 Schizophrenia; TGCT cis rs5750830 0.594 rs9611165 chr22:39775250 A/G cg11247378 chr22:39784982 NA -0.64 -8.48 -0.61 5.71e-14 Intelligence (multi-trait analysis); TGCT cis rs11690935 0.959 rs10206062 chr2:172577276 A/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs2239547 0.603 rs59989280 chr3:53098875 T/C cg10802521 chr3:52805072 NEK4 -0.58 -5.31 -0.43 4.87e-7 Schizophrenia; TGCT cis rs5750830 0.649 rs5750815 chr22:39798449 T/C cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs308403 0.530 rs13135766 chr4:123664427 C/G cg10495464 chr4:123653540 BBS12;LOC729338 -0.67 -6.4 -0.5 2.94e-9 Blood protein levels; TGCT cis rs9467773 1.000 rs1535277 chr6:26567802 G/T cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.792 rs12531315 chr7:1953650 C/G cg22963979 chr7:1858916 MAD1L1 -0.35 -5.4 -0.44 3.3e-7 Bipolar disorder and schizophrenia; TGCT cis rs782590 0.967 rs1823893 chr2:55788921 T/C cg18811423 chr2:55921094 PNPT1 0.67 7.1 0.54 8.63e-11 Metabolic syndrome; TGCT cis rs877282 0.797 rs11253329 chr10:753200 A/T cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.79e-7 Menopause (age at onset); TGCT cis rs4689388 0.890 rs4688991 chr4:6302220 C/G cg00701064 chr4:6280414 WFS1 0.44 5.85 0.47 4.08e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9467711 1.000 rs6903015 chr6:26322526 A/G cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs7000551 0.715 rs2443502 chr8:22340499 G/A cg12081754 chr8:22256438 SLC39A14 0.27 4.54 0.38 1.29e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10744422 1.000 rs7972447 chr12:123354545 C/G cg25930673 chr12:123319894 HIP1R -0.85 -5.09 -0.42 1.29e-6 Schizophrenia; TGCT cis rs473651 0.935 rs482775 chr2:239335403 G/C cg21699342 chr2:239360505 ASB1 0.18 4.9 0.4 2.93e-6 Multiple system atrophy; TGCT cis rs921968 0.643 rs4674321 chr2:219511368 G/A cg02176678 chr2:219576539 TTLL4 0.44 6.16 0.48 9.35e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs832540 0.656 rs6862118 chr5:56106474 G/A cg12311346 chr5:56204834 C5orf35 -0.47 -4.86 -0.4 3.42e-6 Coronary artery disease; TGCT cis rs7246657 0.943 rs1373991 chr19:37838911 T/C cg18154014 chr19:37997991 ZNF793 0.72 5.19 0.42 8.3e-7 Coronary artery calcification; TGCT cis rs9532580 0.778 rs34373380 chr13:41244217 T/A cg21288729 chr13:41239152 FOXO1 1.01 10.56 0.69 5.52e-19 Mean corpuscular hemoglobin; TGCT trans rs6089829 0.888 rs4809268 chr20:61675249 C/G cg13615516 chr5:77269221 NA 0.73 8.39 0.6 9.12e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7666738 0.830 rs11941961 chr4:99065654 G/T cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.9e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs6089829 0.926 rs6062395 chr20:61667904 A/G cg17470723 chr8:74884337 TCEB1 0.71 6.72 0.52 5.96e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs60154123 0.505 rs115881613 chr1:210040369 C/T cg22029157 chr1:209979665 IRF6 0.79 5.78 0.46 5.6e-8 Coronary artery disease; TGCT cis rs2996428 0.667 rs11578070 chr1:3769871 G/C cg17848003 chr1:3704513 LRRC47 0.18 5.15 0.42 9.99e-7 Red cell distribution width; TGCT cis rs4919044 0.641 rs11187232 chr10:94737477 A/G cg05127821 chr10:94822908 CYP26C1 -0.73 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs6089584 0.888 rs6587283 chr20:60613727 A/C cg13770153 chr20:60521292 NA -0.54 -6.99 -0.53 1.51e-10 Body mass index; TGCT cis rs4808199 0.948 rs8108647 chr19:19427623 A/G cg03709012 chr19:19516395 GATAD2A 0.8 6.24 0.49 6.43e-9 Nonalcoholic fatty liver disease; TGCT cis rs7666738 0.680 rs11726233 chr4:99079773 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.15 0.42 9.95e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs907683 0.546 rs1058261 chr2:220285309 C/T cg15015639 chr2:220282977 DES -0.39 -4.83 -0.4 3.88e-6 Resting heart rate; TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg14893161 chr1:205819251 PM20D1 0.55 7.8 0.57 2.23e-12 Menarche (age at onset); TGCT cis rs704 0.628 rs2239908 chr17:26725265 G/A cg10342447 chr17:26645325 TMEM97 -0.47 -4.69 -0.39 7.22e-6 Osteoprotegerin levels; TGCT cis rs4851254 0.660 rs59447631 chr2:100691493 T/C cg07810366 chr2:100720526 AFF3 -0.49 -5.15 -0.42 1e-6 Intelligence (multi-trait analysis); TGCT cis rs6684514 1.000 rs3806407 chr1:156251742 T/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs793571 0.568 rs6494029 chr15:58923206 T/C cg05156742 chr15:59063176 FAM63B 0.56 5.33 0.43 4.43e-7 Schizophrenia; TGCT cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg12310025 chr6:25882481 NA -0.59 -5.91 -0.47 3.03e-8 Blood metabolite levels; TGCT cis rs7558911 0.801 rs3769827 chr2:202102685 A/G cg24599065 chr2:202093848 CASP10 0.21 4.63 0.38 8.94e-6 Chronic lymphocytic leukemia; TGCT cis rs950027 0.620 rs1153860 chr15:45636584 A/G cg14582100 chr15:45693742 SPATA5L1 -0.48 -6.04 -0.48 1.67e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg25036284 chr2:26402008 FAM59B -0.65 -5.18 -0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs875971 1.000 rs778726 chr7:65828731 C/T cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.11e-6 Aortic root size; TGCT cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.01 0.48 1.9e-8 Bipolar disorder; TGCT cis rs73058052 1.000 rs73057994 chr19:50091273 C/A cg09250473 chr19:50168907 IRF3;BCL2L12 0.87 6.6 0.51 1.06e-9 Fibrinogen levels; TGCT cis rs2204008 0.754 rs11181643 chr12:38380553 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.72e-11 Bladder cancer; TGCT cis rs9467773 0.626 rs9379860 chr6:26370605 T/C cg05738196 chr6:26577821 NA -0.63 -6.8 -0.52 3.97e-10 Intelligence (multi-trait analysis); TGCT cis rs7020830 0.898 rs13290794 chr9:37183628 C/T cg14294708 chr9:37120828 ZCCHC7 1.24 17.13 0.84 1.79e-34 Schizophrenia; TGCT cis rs3763267 0.649 rs73038057 chr6:169569765 C/T cg02129017 chr6:168983500 SMOC2 -0.42 -4.45 -0.37 1.86e-5 Blood protein levels; TGCT cis rs1401999 0.659 rs7622660 chr3:183753337 C/T cg20387954 chr3:183756860 HTR3D 0.23 4.95 0.41 2.35e-6 Anterior chamber depth; TGCT cis rs909002 0.849 rs4949449 chr1:32088534 T/G cg11573219 chr1:32083031 HCRTR1 -0.49 -6.41 -0.5 2.78e-9 Intelligence (multi-trait analysis); TGCT cis rs112217694 1.000 rs79743141 chr4:104642724 G/A cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs8179 0.761 rs42035 chr7:92239531 A/G cg15732164 chr7:92237376 CDK6 -0.3 -5.34 -0.43 4.37e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2729354 0.953 rs2649650 chr11:57327567 C/T cg24343310 chr11:57249947 NA 0.29 4.92 0.4 2.73e-6 Blood protein levels; TGCT cis rs1552244 0.572 rs68121641 chr3:10165845 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs854765 0.647 rs1008136 chr17:18027142 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.6 0.56 6.35e-12 Total body bone mineral density; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs854765 0.964 rs12943202 chr17:17994332 T/A cg04398451 chr17:18023971 MYO15A 0.3 4.67 0.39 7.62e-6 Total body bone mineral density; TGCT cis rs75686122 1.000 rs75686122 chr8:104573789 C/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs3820068 0.581 rs59684759 chr1:15919893 A/G cg05660106 chr1:15850417 CASP9 0.84 8.27 0.6 1.8e-13 Systolic blood pressure; TGCT cis rs1355223 0.583 rs2941044 chr11:34867444 A/C cg24088639 chr11:34937564 PDHX;APIP -0.51 -4.64 -0.38 8.76e-6 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs10489202 0.608 rs10800334 chr1:168075613 T/C cg24449463 chr1:168025552 DCAF6 -0.52 -5.41 -0.44 3.13e-7 Schizophrenia; TGCT trans rs9765602 1 rs9765602 chr5:35426631 A/G cg10378735 chr7:142558305 EPHB6 0.87 6.79 0.52 4.14e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs3902035 0.964 rs62423999 chr6:119013532 A/G cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7659604 0.539 rs3217753 chr4:122746325 A/G cg06713675 chr4:122721982 EXOSC9 -0.68 -9.22 -0.64 9.56e-16 Type 2 diabetes; TGCT cis rs514406 0.679 rs541852 chr1:53256834 A/G cg24675658 chr1:53192096 ZYG11B 0.89 11.76 0.73 6.48e-22 Monocyte count; TGCT cis rs4132509 0.793 rs7538011 chr1:243703344 A/G cg21452805 chr1:244014465 NA 0.75 4.55 0.38 1.28e-5 RR interval (heart rate); TGCT cis rs13188771 0.525 rs10477735 chr5:100918100 T/C cg10455971 chr5:101119566 NA 0.46 4.6 0.38 1.02e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7772486 0.790 rs6926076 chr6:146232804 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.861 rs35517489 chr1:53304062 G/C cg24675658 chr1:53192096 ZYG11B -0.71 -7.89 -0.58 1.32e-12 Monocyte count; TGCT cis rs6074578 0.679 rs2298108 chr20:138125 G/T cg16931068 chr20:139680 DEFB127 0.27 4.71 0.39 6.51e-6 Hirschsprung disease; TGCT cis rs7091068 1.000 rs7091068 chr10:95420385 G/T cg20715218 chr10:95462985 C10orf4 0.5 4.56 0.38 1.21e-5 Urinary tract infection frequency; TGCT cis rs72781680 1.000 rs72781658 chr2:24220141 A/G cg08917208 chr2:24149416 ATAD2B 0.84 5.12 0.42 1.12e-6 Lymphocyte counts; TGCT cis rs9393692 0.578 rs806795 chr6:26205293 G/A cg00631329 chr6:26305371 NA -0.31 -4.55 -0.38 1.26e-5 Educational attainment; TGCT cis rs7552404 0.920 rs1612097 chr1:76218875 C/T cg10523679 chr1:76189770 ACADM 0.84 9.05 0.63 2.44e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6459788 0.720 rs11768765 chr7:157253133 C/T cg06271696 chr7:157225062 NA -0.27 -4.91 -0.4 2.85e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7914558 1.000 rs12255047 chr10:104760752 G/A cg15744005 chr10:104629667 AS3MT -0.41 -5.08 -0.42 1.33e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10984561 0.881 rs73540254 chr9:122255448 C/G cg14242995 chr9:122249943 NA 0.72 5.82 0.46 4.75e-8 Pulmonary function decline; TGCT cis rs7547997 0.615 rs35752748 chr1:158321565 A/C cg07950803 chr1:158223934 CD1A 0.31 4.66 0.39 8.18e-6 QRS duration; TGCT cis rs2594989 0.779 rs2437685 chr3:11593013 A/G cg00170343 chr3:11313890 ATG7 0.67 5.09 0.42 1.28e-6 Circulating chemerin levels; TGCT cis rs7830933 0.780 rs6983481 chr8:23609009 G/T cg04349084 chr8:23602677 NA 0.26 5.13 0.42 1.09e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs2439831 0.867 rs2260160 chr15:43895643 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.97 7.11 0.54 8.02e-11 Lung cancer in ever smokers; TGCT cis rs7635838 0.617 rs2594971 chr3:11313910 G/A cg00170343 chr3:11313890 ATG7 0.61 5.98 0.47 2.16e-8 HDL cholesterol; TGCT cis rs2439831 0.867 rs3213991 chr15:43670280 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs68170813 0.522 rs12535814 chr7:107038432 A/T cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs682748 0.846 rs6893755 chr5:17140421 A/T cg23987134 chr5:17158319 LOC285696 -0.21 -5.19 -0.42 8.4e-7 Hippocampal atrophy; TGCT cis rs6840360 0.837 rs13137669 chr4:152710943 A/G cg22705602 chr4:152727874 NA -0.24 -4.45 -0.37 1.86e-5 Intelligence (multi-trait analysis); TGCT cis rs6087990 0.806 rs4911259 chr20:31376282 A/C cg13636640 chr20:31349939 DNMT3B 0.99 12.23 0.74 4.84e-23 Ulcerative colitis; TGCT cis rs9926296 0.609 rs4785710 chr16:89796756 C/T cg03388025 chr16:89894329 SPIRE2 -0.32 -4.84 -0.4 3.86e-6 Vitiligo; TGCT cis rs1348850 0.519 rs1527406 chr2:178525655 C/T cg22681709 chr2:178499509 PDE11A -0.48 -6.08 -0.48 1.36e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4665809 1.000 rs4233708 chr2:26291345 C/T cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs921968 0.509 rs655441 chr2:219357545 C/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6089829 0.890 rs6062775 chr20:61663650 T/C cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs250677 0.687 rs10040624 chr5:148437579 A/G cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs939658 0.935 rs954292 chr15:79449237 C/T cg17916960 chr15:79447300 NA 0.55 8.85 0.62 7.63e-15 Refractive error; TGCT cis rs12142240 0.698 rs1135459 chr1:46815930 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.78 7.09 0.54 8.96e-11 Prudent dietary pattern; TGCT cis rs926938 0.520 rs6660624 chr1:115272163 G/A cg12756093 chr1:115239321 AMPD1 -0.41 -4.93 -0.4 2.62e-6 Autism; TGCT cis rs2243480 1.000 rs7792391 chr7:65773429 A/G cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg06753367 chr22:24256600 NA -0.24 -4.66 -0.39 7.89e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.645 rs28436748 chr11:50046422 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs2180341 0.920 rs7756880 chr6:127683999 A/T cg24812749 chr6:127587940 RNF146 1.01 7.62 0.56 5.59e-12 Breast cancer; TGCT cis rs6671200 0.607 rs3767315 chr1:95705972 A/G cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs9517320 0.534 rs9554477 chr13:99160379 C/T cg07423050 chr13:99094983 FARP1 -0.29 -5.8 -0.46 5.2e-8 Longevity; TGCT cis rs4919694 1.000 rs75691516 chr10:104652045 C/T cg04362960 chr10:104952993 NT5C2 1.03 6.95 0.53 1.83e-10 Arsenic metabolism; TGCT cis rs8072100 0.713 rs2136750 chr17:45456100 A/G cg08085267 chr17:45401833 C17orf57 -0.51 -5.6 -0.45 1.3e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1577917 0.958 rs12208227 chr6:86670944 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.24 -0.43 6.64e-7 Response to antipsychotic treatment; TGCT cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg13695892 chr22:41940480 POLR3H 0.87 8.24 0.59 2.06e-13 Vitiligo; TGCT cis rs12643440 0.538 rs4435747 chr4:17139645 C/T cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs2439831 1.000 rs2467426 chr15:43989518 A/G cg19166733 chr15:44192098 FRMD5 -0.25 -4.56 -0.38 1.21e-5 Lung cancer in ever smokers; TGCT cis rs7208859 0.673 rs73263776 chr17:29211331 G/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7923609 0.967 rs2393966 chr10:65134814 T/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.15e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2688608 0.967 rs2633299 chr10:75656754 T/G cg23231163 chr10:75533350 FUT11 -0.25 -4.45 -0.37 1.89e-5 Inflammatory bowel disease; TGCT cis rs7119038 0.818 rs4936444 chr11:118743338 A/G cg19308663 chr11:118741387 NA -0.33 -6.63 -0.51 9.3e-10 Sjögren's syndrome; TGCT cis rs2229238 0.911 rs4390168 chr1:154509096 A/G cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT trans rs9593057 0.892 rs720506 chr13:35619734 T/C cg02044145 chr5:176520341 FGFR4 0.42 6.62 0.51 9.8e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6121246 0.559 rs6087771 chr20:30306724 A/G cg13852791 chr20:30311386 BCL2L1 0.84 7.74 0.57 3.08e-12 Mean corpuscular hemoglobin; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.51 5.51 0.44 2.02e-7 Lymphocyte counts; TGCT cis rs3213545 0.659 rs2259693 chr12:121457995 G/A cg02403541 chr12:121454288 C12orf43 0.7 7.9 0.58 1.3e-12 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs8105265 1 rs8105265 chr19:2920705 A/G cg08634464 chr19:2901147 ZNF57 1.37 7.75 0.57 2.79e-12 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs13191362 0.935 rs35049401 chr6:162968464 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.64 4.8 0.4 4.48e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4665809 0.590 rs11552518 chr2:26455127 G/A cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs4631830 0.863 rs6481329 chr10:51529746 G/A cg10326726 chr10:51549505 MSMB -0.26 -5.3 -0.43 5.17e-7 Prostate-specific antigen levels; TGCT cis rs3733585 0.673 rs9994937 chr4:9964799 G/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.56 -0.56 7.77e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs28595532 0.702 rs56217716 chr4:119338490 T/G cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs12643440 0.538 rs12650732 chr4:17141641 A/T cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs12477438 0.798 rs896886 chr2:99652713 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.71 6.27 0.49 5.34e-9 Chronic sinus infection; TGCT cis rs1552244 0.554 rs2272119 chr3:10049352 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs7100689 0.784 rs10749562 chr10:82108253 G/T cg01528321 chr10:82214614 TSPAN14 0.8 8.0 0.58 7.5e-13 Post bronchodilator FEV1; TGCT cis rs12477438 0.798 rs4324365 chr2:99623845 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs2153535 0.580 rs4140586 chr6:8503192 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs308403 0.509 rs10016979 chr4:123673192 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.84 0.73 4.22e-22 Blood protein levels; TGCT cis rs2153535 0.580 rs1335628 chr6:8491742 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9486719 0.843 rs2103539 chr6:96844342 T/A cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs10504229 0.683 rs7463453 chr8:58112053 A/G cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs6840360 0.642 rs2709834 chr4:152375424 T/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs1941023 0.584 rs7935082 chr11:60155000 T/C cg08716584 chr11:60157161 MS4A7 -0.35 -5.29 -0.43 5.3e-7 Congenital heart disease (maternal effect); TGCT cis rs2404602 1.000 rs2404741 chr15:76851735 C/T cg26408565 chr15:76604113 ETFA -0.45 -5.75 -0.46 6.55e-8 Blood metabolite levels; TGCT cis rs8072100 0.790 rs7222225 chr17:45693497 A/G cg10024583 chr17:45772800 TBKBP1 -0.43 -4.47 -0.37 1.76e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs28595532 0.702 rs72670238 chr4:119322751 C/T cg21605333 chr4:119757512 SEC24D 0.79 4.99 0.41 1.96e-6 Cannabis dependence symptom count; TGCT cis rs1005224 0.927 rs1981899 chr14:76175594 G/A cg04684003 chr14:76127793 TTLL5;C14orf1 -0.71 -5.88 -0.47 3.58e-8 Large artery stroke; TGCT cis rs941873 0.868 rs4980063 chr10:81105844 A/T cg09469691 chr10:81107165 PPIF 0.57 5.61 0.45 1.23e-7 Height; TGCT cis rs57590327 0.679 rs17019088 chr3:81611535 A/T cg07356753 chr3:81810745 GBE1 -0.6 -5.29 -0.43 5.38e-7 Extraversion; TGCT cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs826838 1.000 rs7953227 chr12:38946193 G/A cg26384229 chr12:38710491 ALG10B 0.99 9.96 0.67 1.54e-17 Heart rate; TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg24675658 chr1:53192096 ZYG11B -0.74 -9.02 -0.63 2.95e-15 Monocyte count; TGCT cis rs7223966 0.961 rs112709843 chr17:61836936 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.54e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs8070740 1.000 rs8080400 chr17:5328633 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.55 0.38 1.27e-5 Menopause (age at onset); TGCT cis rs9942416 0.660 rs166183 chr5:74977845 T/C cg19683494 chr5:74908142 NA -0.59 -6.29 -0.49 4.99e-9 Age-related disease endophenotypes; TGCT cis rs78456975 0.550 rs11904276 chr2:1524006 T/C cg12573674 chr2:1569213 NA -0.46 -4.63 -0.38 9.04e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2243480 1.000 rs937108 chr7:65428452 G/A cg20637647 chr7:64974828 NA 0.92 5.35 0.43 4.12e-7 Diabetic kidney disease; TGCT cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg20302342 chr1:156215951 PAQR6 0.36 5.38 0.44 3.56e-7 Tonsillectomy; TGCT cis rs7615952 1.000 rs7616044 chr3:125649354 G/C cg05084668 chr3:125655381 ALG1L -0.75 -6.14 -0.48 1.03e-8 Blood pressure (smoking interaction); TGCT cis rs7647973 0.566 rs57630346 chr3:49086215 T/C cg05785598 chr3:49045655 WDR6 0.39 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs2486288 0.656 rs8040185 chr15:45552081 G/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs66887589 0.616 rs6822808 chr4:120217365 C/A cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.17e-5 Diastolic blood pressure; TGCT cis rs7917772 0.503 rs7100753 chr10:104300979 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8180040 0.934 rs12630641 chr3:47534836 G/T cg27129171 chr3:47204927 SETD2 0.66 7.91 0.58 1.22e-12 Colorectal cancer; TGCT cis rs7772486 0.875 rs9403763 chr6:146357655 A/G cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.559 rs5758397 chr22:42019251 C/T cg13695892 chr22:41940480 POLR3H 0.86 8.2 0.59 2.63e-13 Vitiligo; TGCT cis rs4478858 0.684 rs7549245 chr1:31752187 A/G cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs666930 0.519 rs532303 chr1:120265444 A/G cg19096424 chr1:120255104 PHGDH 0.64 5.86 0.47 3.83e-8 Breast cancer; TGCT cis rs2297441 0.550 rs6011097 chr20:62398825 G/A cg14758556 chr20:62440591 NA -0.34 -4.77 -0.39 5.13e-6 Ulcerative colitis; TGCT cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs473651 0.935 rs508483 chr2:239339709 T/C cg18131467 chr2:239335373 ASB1 1.02 15.01 0.8 1.18e-29 Multiple system atrophy; TGCT cis rs13631 0.965 rs7853589 chr9:140003844 A/G cg14289826 chr9:140003911 NA -0.28 -6.64 -0.51 8.94e-10 Cerebrospinal fluid biomarker levels; TGCT trans rs17685 0.672 rs1639623 chr7:75707951 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.04 0.63 2.65e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs270601 0.633 rs733300 chr5:131572243 A/G cg24060327 chr5:131705240 SLC22A5 -0.61 -6.37 -0.5 3.32e-9 Acylcarnitine levels; TGCT cis rs72781680 1.000 rs61739076 chr2:24149439 G/A cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs6500602 0.627 rs3848372 chr16:4587875 C/A cg06139259 chr16:4526053 HMOX2;NMRAL1 0.25 4.65 0.38 8.54e-6 Schizophrenia; TGCT trans rs12339966 0.615 rs1387295 chr9:11284569 C/T cg07173112 chr1:1114698 TTLL10 -0.34 -6.68 -0.51 7.34e-10 Systolic blood pressure; TGCT cis rs4988958 0.565 rs885088 chr2:103039044 A/G cg03938978 chr2:103052716 IL18RAP 0.26 5.26 0.43 6.01e-7 Asthma (childhood onset); TGCT cis rs6500602 0.627 rs841231 chr16:4583147 C/T cg08645402 chr16:4508243 NA -0.21 -5.49 -0.44 2.15e-7 Schizophrenia; TGCT cis rs1322512 0.958 rs74608294 chr6:152944818 T/C cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg10263370 chr3:44754102 ZNF502 -0.47 -5.67 -0.45 9.48e-8 Depressive symptoms; TGCT cis rs6940638 0.688 rs9348750 chr6:27057945 T/G cg26531700 chr6:26746687 NA -0.56 -4.88 -0.4 3.25e-6 Intelligence (multi-trait analysis); TGCT trans rs61931739 0.500 rs11053197 chr12:34441949 C/T cg26384229 chr12:38710491 ALG10B 0.73 6.93 0.53 2e-10 Morning vs. evening chronotype; TGCT cis rs6752107 0.935 rs10199278 chr2:234160669 C/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.86 0.4 3.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6438424 0.521 rs10934426 chr3:117717570 T/G cg15509235 chr3:117715573 NA 0.52 5.11 0.42 1.17e-6 Menarche (age at onset); TGCT cis rs4819052 0.819 rs7279136 chr21:46692287 C/T cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7216064 0.532 rs8065296 chr17:66018562 T/A cg12091567 chr17:66097778 LOC651250 1.06 8.62 0.61 2.69e-14 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9486719 0.843 rs3849198 chr6:97036539 C/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs9303542 0.527 rs62066689 chr17:46609092 T/C cg25032089 chr17:46643351 HOXB3 0.58 5.47 0.44 2.38e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs1372520 0.684 rs3113355 chr4:90745345 A/T cg01966878 chr4:90757139 SNCA -0.3 -4.69 -0.39 7.05e-6 Neuroticism; TGCT cis rs9650657 0.771 rs12542888 chr8:10662555 A/C cg27411982 chr8:10470053 RP1L1 -0.23 -5.04 -0.41 1.59e-6 Neuroticism; TGCT cis rs317689 0.513 rs529268 chr12:69687051 G/A cg11871910 chr12:69753446 YEATS4 0.63 6.11 0.48 1.18e-8 Response to diuretic therapy; TGCT cis rs2404602 0.669 rs12441484 chr15:77109875 G/A cg22467129 chr15:76604101 ETFA -0.46 -5.22 -0.42 7.3e-7 Blood metabolite levels; TGCT trans rs916888 0.821 rs199504 chr17:44861003 C/T cg22433210 chr17:43662623 NA -1.01 -7.25 -0.55 3.83e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs854765 0.647 rs854769 chr17:18019011 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.67 -6.95 -0.53 1.87e-10 Total body bone mineral density; TGCT cis rs11690935 0.959 rs66835971 chr2:172677459 G/A cg13550731 chr2:172543902 DYNC1I2 -1.16 -12.07 -0.74 1.15e-22 Schizophrenia; TGCT cis rs9527 0.830 rs12249194 chr10:104643698 T/C cg15744005 chr10:104629667 AS3MT -0.51 -6.04 -0.48 1.63e-8 Arsenic metabolism; TGCT cis rs9560113 1.000 rs11069895 chr13:112178824 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs3806843 0.576 rs246041 chr5:140331128 C/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10992471 0.639 rs10125587 chr9:95499882 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.48 -0.44 2.27e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs78487399 0.808 rs6705351 chr2:43843137 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.53 0.38 1.39e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1696756 0.816 rs2650242 chr17:77827360 A/T cg00646381 chr17:77835854 NA 0.43 6.11 0.48 1.21e-8 Glucocorticoid-induced osteonecrosis (age 10 years and older); TGCT cis rs12477438 0.501 rs6727749 chr2:99793590 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg16405210 chr4:1374714 KIAA1530 -0.25 -4.5 -0.37 1.54e-5 Longevity; TGCT cis rs7178572 0.568 rs12443386 chr15:77491389 C/T cg22256960 chr15:77711686 NA 0.89 8.92 0.63 4.95e-15 Type 2 diabetes; TGCT cis rs9914988 0.832 rs34267753 chr17:27157586 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2255336 0.938 rs2126888 chr12:10546388 A/G cg16084090 chr12:10586130 KLRC2 0.28 4.46 0.37 1.81e-5 Blood protein levels; TGCT cis rs2013441 1.000 rs2703791 chr17:20163529 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs8062405 1.000 rs2008514 chr16:28825605 A/G cg09754948 chr16:28834200 ATXN2L -0.62 -4.69 -0.39 7.18e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2204008 0.837 rs11612125 chr12:38213212 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg04389838 chr3:44770851 ZNF501 -0.4 -5.36 -0.43 3.87e-7 Depressive symptoms; TGCT cis rs919433 0.647 rs13404366 chr2:198522632 A/G cg00792783 chr2:198669748 PLCL1 0.56 4.85 0.4 3.64e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs7937682 0.575 rs34888817 chr11:111756455 C/T cg09085632 chr11:111637200 PPP2R1B 0.92 8.7 0.62 1.7e-14 Primary sclerosing cholangitis; TGCT cis rs7845219 0.544 rs4735330 chr8:95917770 A/C cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs2997447 0.655 rs1317709 chr1:26384690 A/C cg19633962 chr1:26362018 EXTL1 -0.62 -4.55 -0.38 1.28e-5 QRS complex (12-leadsum); TGCT cis rs67311347 1.000 rs13324109 chr3:40460767 T/C cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs9291683 0.530 rs882223 chr4:9981625 A/C cg00071950 chr4:10020882 SLC2A9 0.65 8.23 0.59 2.21e-13 Bone mineral density; TGCT cis rs7914558 0.966 rs4917997 chr10:104945213 A/G cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.65e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs8031584 0.578 rs1088473 chr15:31139298 A/G cg08109568 chr15:31115862 NA 0.38 5.03 0.41 1.67e-6 Huntington's disease progression; TGCT cis rs6669072 0.647 rs1335727 chr1:91238652 C/T cg08895590 chr1:91227319 NA -0.32 -4.45 -0.37 1.86e-5 Cognitive function; TGCT cis rs9868809 0.881 rs7631574 chr3:48663046 A/G cg00383909 chr3:49044727 WDR6 -0.84 -4.7 -0.39 6.72e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs12620999 1.000 rs4377286 chr2:238069686 C/T cg23555395 chr2:238036564 NA -0.3 -5.16 -0.42 9.38e-7 Systemic lupus erythematosus; TGCT trans rs3780486 0.801 rs28517717 chr9:33179451 C/T cg04842962 chr6:43655489 MRPS18A 1.12 12.06 0.73 1.25e-22 IgG glycosylation; TGCT cis rs8084125 0.832 rs62105174 chr18:74948324 G/A cg05528293 chr18:74961138 GALR1 0.52 5.2 0.42 8.04e-7 Obesity-related traits; TGCT cis rs11779988 0.545 rs454692 chr8:17789298 T/C cg01800426 chr8:17659068 MTUS1 -0.7 -5.46 -0.44 2.5e-7 Breast cancer; TGCT cis rs35306767 0.668 rs12356612 chr10:1055055 C/T cg20503657 chr10:835505 NA 0.57 6.65 0.51 8.47e-10 Eosinophil percentage of granulocytes; TGCT cis rs6484504 0.576 rs158140 chr11:31212971 T/C cg26647111 chr11:31128758 NA -0.34 -4.62 -0.38 9.36e-6 Red blood cell count; TGCT trans rs1814175 0.765 rs1722003 chr11:49895896 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.15 -0.59 3.33e-13 Height; TGCT trans rs117132860 0.661 rs28826706 chr7:17121097 T/G cg25519926 chr7:130132360 MEST;MESTIT1 0.95 6.71 0.52 6.21e-10 Cutaneous squamous cell carcinoma; TGCT cis rs60871478 0.588 rs6952577 chr7:872100 C/T cg00475322 chr7:917719 C7orf20 -0.49 -4.79 -0.39 4.72e-6 Cerebrospinal P-tau181p levels; TGCT cis rs2637266 0.967 rs4608018 chr10:78376110 T/C cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs694739 1.000 rs11231757 chr11:64106317 C/T cg23796481 chr11:64053134 BAD;GPR137 0.68 7.03 0.53 1.25e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs7617773 0.539 rs13087050 chr3:48392800 C/T cg11946769 chr3:48343235 NME6 0.6 5.01 0.41 1.82e-6 Coronary artery disease; TGCT cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg02725872 chr8:58115012 NA -0.39 -4.83 -0.4 3.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs12479064 0.724 rs737094 chr2:100089078 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.69 -5.83 -0.46 4.53e-8 Chronic sinus infection; TGCT cis rs709400 0.663 rs62007718 chr14:103940436 G/A cg26031613 chr14:104095156 KLC1 0.86 9.73 0.66 5.62e-17 Body mass index; TGCT cis rs7582180 0.629 rs36103184 chr2:100942634 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs617219 0.710 rs2166344 chr5:78534134 T/G cg23987322 chr5:78407566 BHMT 0.35 4.69 0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1670533 1.000 rs6837145 chr4:1071067 T/C cg27284194 chr4:1044797 NA 0.68 5.85 0.47 4.09e-8 Recombination rate (females); TGCT cis rs11190604 0.767 rs10883490 chr10:102194775 C/T cg16342193 chr10:102329863 NA -0.42 -5.26 -0.43 6.02e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4566357 0.595 rs10206912 chr2:227921095 A/T cg11843606 chr2:227700838 RHBDD1 -0.53 -4.83 -0.4 3.92e-6 Coronary artery disease; TGCT cis rs896854 0.517 rs2013597 chr8:95951807 G/A cg16049864 chr8:95962084 TP53INP1 -0.54 -5.95 -0.47 2.54e-8 Type 2 diabetes; TGCT cis rs1153858 1.000 rs7169818 chr15:45640191 G/A cg14582100 chr15:45693742 SPATA5L1 0.47 5.65 0.45 1.05e-7 Homoarginine levels; TGCT cis rs2836974 0.897 rs13049280 chr21:40594656 C/G cg11890956 chr21:40555474 PSMG1 1.04 10.93 0.7 6.96e-20 Cognitive function; TGCT cis rs909674 0.818 rs5757678 chr22:39843409 A/G cg05872129 chr22:39784769 NA 0.96 9.61 0.65 1.09e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7937612 1.000 rs6589812 chr11:120278359 T/C cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.44 -0.37 1.96e-5 Intraocular pressure; TGCT cis rs6089584 0.888 rs6089624 chr20:60619907 C/G cg13770153 chr20:60521292 NA -0.54 -7.11 -0.54 7.9e-11 Body mass index; TGCT cis rs1801251 1.000 rs2675974 chr2:233727071 A/G cg25237894 chr2:233734115 C2orf82 0.31 5.47 0.44 2.36e-7 Coronary artery disease; TGCT cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs669446 0.622 rs623965 chr1:44111187 A/G cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs910316 0.934 rs8006587 chr14:75664939 A/G cg08847533 chr14:75593920 NEK9 0.95 9.85 0.66 2.89e-17 Height; TGCT cis rs9814567 0.537 rs9879993 chr3:134162559 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.72 7.4 0.55 1.82e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs60871478 1.000 rs62432252 chr7:802886 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.45 4.56 0.38 1.21e-5 Cerebrospinal P-tau181p levels; TGCT cis rs40363 0.645 rs250627 chr16:3527050 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.61 -4.49 -0.37 1.6e-5 Tuberculosis; TGCT cis rs4665630 0.522 rs747622 chr2:23881466 G/C cg08063864 chr2:24346004 PFN4;LOC375190 -1.28 -5.96 -0.47 2.43e-8 Hypertension; TGCT cis rs6964587 0.626 rs10225241 chr7:91524940 A/G cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg20607798 chr8:58055168 NA 0.44 4.53 0.38 1.36e-5 Developmental language disorder (linguistic errors); TGCT cis rs13102973 0.645 rs11734870 chr4:135885118 T/A cg14419869 chr4:135874104 NA 0.26 4.55 0.38 1.28e-5 Subjective well-being; TGCT cis rs7552404 0.655 rs5745336 chr1:76273519 G/A cg03433033 chr1:76189801 ACADM 0.66 6.88 0.53 2.57e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7659604 0.967 rs34949254 chr4:122664344 G/A cg19748678 chr4:122722346 EXOSC9 0.57 5.54 0.45 1.69e-7 Type 2 diabetes; TGCT trans rs6089829 0.962 rs6122344 chr20:61661738 C/T cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.505 rs856721 chr1:53162156 C/A cg01802117 chr1:53393560 SCP2 -0.42 -4.86 -0.4 3.51e-6 Monocyte count; TGCT cis rs597539 0.652 rs654071 chr11:68653432 A/C cg06028808 chr11:68637592 NA 0.51 6.54 0.51 1.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2204008 0.774 rs3910796 chr12:38230660 G/T cg13010199 chr12:38710504 ALG10B 0.62 4.91 0.4 2.81e-6 Bladder cancer; TGCT cis rs6987853 0.865 rs2923445 chr8:42400743 C/A cg20539142 chr8:42623718 CHRNA6 -0.19 -4.58 -0.38 1.11e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs114540395 0.925 rs78646802 chr10:103392029 A/G cg03300883 chr10:102748874 C10orf2 0.42 4.63 0.38 9.24e-6 Schizophrenia; TGCT cis rs3806843 1.000 rs12717860 chr5:140171442 C/T cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9467773 1.000 rs6922824 chr6:26553815 C/G cg05738196 chr6:26577821 NA -0.9 -13.24 -0.77 1.71e-25 Intelligence (multi-trait analysis); TGCT cis rs2970818 0.831 rs4238020 chr12:4616642 C/T cg02722637 chr12:4922070 KCNA6 -0.32 -4.58 -0.38 1.11e-5 Phosphorus levels; TGCT cis rs12477438 0.501 rs11123770 chr2:99825102 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.98 12.5 0.75 1.03e-23 Chronic sinus infection; TGCT trans rs4650994 0.816 rs2811303 chr1:178595646 G/T cg05059571 chr16:84539110 KIAA1609 0.4 7.44 0.56 1.49e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs1218582 0.772 rs10908448 chr1:154882544 A/G cg09359103 chr1:154839909 KCNN3 0.63 11.15 0.71 1.98e-20 Prostate cancer; TGCT cis rs826838 0.967 rs4768329 chr12:39129394 T/C cg13010199 chr12:38710504 ALG10B -0.64 -5.11 -0.42 1.19e-6 Heart rate; TGCT cis rs12135062 0.687 rs6685614 chr1:3108517 C/T cg25382214 chr1:3105252 PRDM16 0.28 4.87 0.4 3.27e-6 Migraine; TGCT trans rs7726839 0.540 rs72705102 chr5:659437 T/C cg25482853 chr8:67687455 SGK3 1.22 10.31 0.68 2.2e-18 Obesity-related traits; TGCT cis rs2406342 0.528 rs75536638 chr18:74499060 G/T cg16472389 chr18:74514291 NA 0.52 5.27 0.43 5.81e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (cisplatin); TGCT cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs4788570 0.667 rs4788557 chr16:71804802 C/T cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs2816062 0.813 rs2816040 chr1:18889536 C/T cg18795169 chr1:18902165 NA 0.6 14.18 0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs10789491 1.000 rs10789491 chr1:47179310 A/G cg15501359 chr1:47185051 KIAA0494 0.81 8.34 0.6 1.19e-13 Response to hepatitis C treatment; TGCT cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs116095464 0.542 rs28650039 chr5:273954 C/A cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs12220898 0.679 rs4582889 chr10:50475014 A/C cg06072769 chr10:50146962 WDFY4 0.36 4.67 0.39 7.64e-6 Inflammatory biomarkers; TGCT cis rs62244186 0.715 rs11130032 chr3:44704083 G/A cg10263370 chr3:44754102 ZNF502 -0.41 -4.79 -0.39 4.73e-6 Depressive symptoms; TGCT cis rs1008375 0.898 rs7670500 chr4:17586957 A/G cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg20887711 chr4:1340912 KIAA1530 0.91 7.94 0.58 1.06e-12 Longevity; TGCT cis rs7296418 0.517 rs73231928 chr12:123724325 T/C cg00376283 chr12:123451042 ABCB9 0.73 6.5 0.5 1.75e-9 Platelet count; TGCT cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.91 -10.66 -0.69 3.08e-19 Menarche (age at onset); TGCT cis rs7954584 0.813 rs1523261 chr12:122462877 C/A cg22168489 chr12:122356033 WDR66 0.2 4.72 0.39 6.21e-6 Mean corpuscular volume; TGCT cis rs7582180 0.638 rs6734316 chr2:100976210 A/G cg14675211 chr2:100938903 LONRF2 0.47 4.55 0.38 1.27e-5 Intelligence (multi-trait analysis); TGCT cis rs8103278 0.507 rs4802275 chr19:46260375 C/T cg14061069 chr19:46274453 DMPK 0.63 11.0 0.7 4.62e-20 Coronary artery disease; TGCT cis rs710216 0.843 rs2297972 chr1:43418026 C/T cg03128534 chr1:43423976 SLC2A1 -0.61 -5.02 -0.41 1.79e-6 Red cell distribution width; TGCT cis rs9811920 0.683 rs793439 chr3:99637783 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.45 -5.33 -0.43 4.52e-7 Axial length; TGCT cis rs3008870 0.792 rs72673729 chr1:67441673 T/TG cg03991309 chr1:68237761 GNG12 -0.27 -4.51 -0.38 1.48e-5 Lymphocyte percentage of white cells; TGCT cis rs12497850 0.931 rs6414613 chr3:49035885 C/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.41 -0.44 3.15e-7 Parkinson's disease; TGCT cis rs3753275 0.624 rs6664000 chr1:8858532 C/T cg17029193 chr1:8510607 RERE -0.31 -4.46 -0.37 1.8e-5 Educational attainment; TGCT cis rs3820928 0.874 rs6728239 chr2:227856552 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs1949733 1.000 rs2631758 chr4:8495304 G/A cg11789530 chr4:8429930 ACOX3 -0.59 -5.43 -0.44 2.83e-7 Response to antineoplastic agents; TGCT trans rs7618501 0.633 rs55751738 chr3:49972101 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.4 0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs7633770 0.805 rs12330414 chr3:46662428 T/C cg11219411 chr3:46661640 NA 0.35 5.07 0.41 1.43e-6 Coronary artery disease; TGCT trans rs1814175 0.791 rs10839468 chr11:49986288 A/G cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs9400467 0.537 rs17606481 chr6:111542388 A/G cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs7659604 0.540 rs10012775 chr4:122676878 T/C cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT trans rs877282 1.000 rs12779159 chr10:772143 T/C cg22713356 chr15:30763199 NA 1.16 9.82 0.66 3.37e-17 Uric acid levels; TGCT cis rs875971 0.660 rs801190 chr7:66033033 C/T cg00343986 chr7:65444356 GUSB -0.24 -5.29 -0.43 5.43e-7 Aortic root size; TGCT cis rs709400 1.000 rs861538 chr14:104166733 C/T cg26031613 chr14:104095156 KLC1 1.13 16.84 0.83 7.59e-34 Body mass index; TGCT cis rs1570884 1.000 rs1570884 chr13:50121511 A/G cg08779649 chr13:50194554 NA 0.34 5.39 0.44 3.46e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.0 8.22 0.59 2.32e-13 Platelet count; TGCT cis rs4689388 0.853 rs11729672 chr4:6293838 A/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7010267 0.570 rs7009768 chr8:120041303 G/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs17221829 0.733 rs12365125 chr11:89359929 C/T cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs2153535 0.525 rs1335644 chr6:8488041 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7412746 0.658 rs12067685 chr1:150952917 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 4.88 0.4 3.17e-6 Melanoma; TGCT cis rs9926296 0.528 rs4785721 chr16:89839997 G/A cg04287289 chr16:89883240 FANCA 0.94 11.87 0.73 3.65e-22 Vitiligo; TGCT cis rs6815814 0.731 rs11734342 chr4:38773109 A/G cg02016764 chr4:38805732 TLR1 -0.28 -4.79 -0.4 4.63e-6 Breast cancer; TGCT cis rs9303401 0.527 rs34835800 chr17:56764990 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.61 5.41 0.44 3.12e-7 Cognitive test performance; TGCT cis rs9858542 1.000 rs9858542 chr3:49701983 A/G cg03060546 chr3:49711283 APEH 0.67 6.09 0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1670533 1.000 rs935970 chr4:1045323 C/G cg27284194 chr4:1044797 NA -0.67 -5.68 -0.45 9.03e-8 Recombination rate (females); TGCT cis rs36051895 0.632 rs10118789 chr9:5141178 G/A cg02405213 chr9:5042618 JAK2 -0.7 -9.44 -0.65 2.91e-16 Pediatric autoimmune diseases; TGCT cis rs66573146 1.000 rs73088528 chr4:6967747 G/C cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs16910800 0.731 rs56067480 chr11:23190184 C/T cg20040320 chr11:23191996 NA -0.51 -4.47 -0.37 1.71e-5 Cancer; TGCT cis rs1153858 1.000 rs12591058 chr15:45640172 T/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg11644478 chr21:40555479 PSMG1 0.64 5.93 0.47 2.86e-8 Cognitive function; TGCT cis rs3812831 0.662 rs407531 chr13:114929218 G/A cg06611532 chr13:114900021 NA 0.36 6.4 0.5 2.95e-9 Schizophrenia; TGCT cis rs6840360 0.550 rs4696288 chr4:152621150 A/C cg17479576 chr4:152424074 FAM160A1 -0.67 -6.69 -0.52 6.7e-10 Intelligence (multi-trait analysis); TGCT cis rs941408 0.515 rs1005556 chr19:2778543 G/T cg26465405 chr19:3039745 TLE2 -0.22 -4.52 -0.38 1.41e-5 Total cholesterol levels; TGCT cis rs3771570 0.642 rs56241013 chr2:242185311 T/C cg21155796 chr2:242212141 HDLBP 0.89 5.45 0.44 2.64e-7 Prostate cancer; TGCT cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg10560079 chr2:191398806 TMEM194B -0.35 -4.97 -0.41 2.21e-6 Pulse pressure; TGCT cis rs9303542 0.559 rs12939811 chr17:46607958 A/T cg25032089 chr17:46643351 HOXB3 0.59 5.6 0.45 1.31e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7617773 0.514 rs11130166 chr3:48388056 A/G cg11946769 chr3:48343235 NME6 0.56 4.75 0.39 5.46e-6 Coronary artery disease; TGCT cis rs7513165 0.935 rs7538055 chr1:204161069 A/G cg04791601 chr1:204159016 NA 0.26 5.21 0.42 7.68e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs9818758 0.607 rs13077498 chr3:49313978 C/T cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7698623 0.850 rs6821260 chr4:88787439 T/C cg27387453 chr4:88533842 DSPP -0.62 -4.64 -0.38 8.66e-6 Cardiovascular disease risk factors; TGCT cis rs10186029 0.676 rs10932464 chr2:213968315 T/A cg08319019 chr2:214017104 IKZF2 0.63 5.79 0.46 5.4e-8 Systemic sclerosis; TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg14159672 chr1:205819179 PM20D1 0.58 7.07 0.54 9.96e-11 Menarche (age at onset); TGCT cis rs6430585 0.527 rs961360 chr2:136393658 A/G cg07169764 chr2:136633963 MCM6 0.98 8.33 0.6 1.3e-13 Corneal structure; TGCT cis rs727563 0.593 rs132770 chr22:42017264 A/G cg13695892 chr22:41940480 POLR3H 0.85 8.03 0.58 6.49e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2439831 0.867 rs2264876 chr15:43757419 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.81 5.66 0.45 9.81e-8 Lung cancer in ever smokers; TGCT cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg07507251 chr3:52567010 NT5DC2 0.45 6.3 0.49 4.7e-9 Electroencephalogram traits; TGCT cis rs6977660 0.714 rs12666488 chr7:19788403 G/A cg05791153 chr7:19748676 TWISTNB 0.84 4.86 0.4 3.49e-6 Thyroid stimulating hormone; TGCT trans rs1973993 0.967 rs11165643 chr1:96924097 C/T cg10631902 chr5:14652156 NA 0.32 7.41 0.55 1.75e-11 Weight; TGCT cis rs3096299 0.933 rs28608022 chr16:89454292 C/T cg02187348 chr16:89574699 SPG7 0.49 4.7 0.39 6.79e-6 Multiple myeloma (IgH translocation); TGCT cis rs909341 0.909 rs1295810 chr20:62330484 G/A cg14758556 chr20:62440591 NA 0.29 4.45 0.37 1.92e-5 Atopic dermatitis; TGCT cis rs9430161 0.598 rs34350247 chr1:11034460 A/G cg27631724 chr1:11040367 C1orf127 0.52 5.95 0.47 2.57e-8 Ewing sarcoma; TGCT trans rs7726839 0.794 rs11739663 chr5:594083 A/G cg25482853 chr8:67687455 SGK3 0.97 7.68 0.57 4.21e-12 Obesity-related traits; TGCT cis rs7267979 0.966 rs2261785 chr20:25262403 C/T cg14121845 chr20:25566513 NINL 0.51 5.5 0.44 2.04e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2013441 1.000 rs1373147 chr17:20206645 T/A cg23224458 chr17:20280056 CCDC144C -0.41 -4.88 -0.4 3.25e-6 Obesity-related traits; TGCT cis rs1903068 0.853 rs12331471 chr4:56001509 T/C cg01777861 chr4:56023843 NA 0.54 6.38 0.5 3.2e-9 Endometriosis; TGCT cis rs7100689 0.646 rs1953971 chr10:82145647 G/C cg01528321 chr10:82214614 TSPAN14 0.78 7.86 0.58 1.56e-12 Post bronchodilator FEV1; TGCT cis rs9303401 0.659 rs8074016 chr17:56840587 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7552404 1.000 rs437298 chr1:76113770 T/C cg10523679 chr1:76189770 ACADM -0.92 -10.05 -0.67 9.78e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17376456 0.877 rs35075119 chr5:93385457 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs7798223 chr7:106829223 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.73 -0.46 7.17e-8 Coronary artery disease; TGCT cis rs4819052 0.851 rs7275874 chr21:46671223 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2637266 1.000 rs1873461 chr10:78338966 A/C cg18941641 chr10:78392320 NA -0.38 -4.73 -0.39 6.01e-6 Pulmonary function; TGCT cis rs9650657 0.770 rs6601529 chr8:10670550 A/G cg27411982 chr8:10470053 RP1L1 -0.23 -5.28 -0.43 5.51e-7 Neuroticism; TGCT trans rs561341 1.000 rs72821971 chr17:30269343 T/G cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs7308134 0.766 rs73036228 chr12:1991782 G/A cg09189752 chr12:2113749 DCP1B -0.57 -4.44 -0.37 1.93e-5 QRS duration in Tripanosoma cruzi seropositivity; TGCT cis rs10754283 0.967 rs6428559 chr1:90099036 C/T cg03145924 chr1:90228473 NA -0.4 -4.47 -0.37 1.75e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs4700695 0.545 rs29441 chr5:65509116 G/T cg21114390 chr5:65439923 SFRS12 -0.79 -7.22 -0.54 4.7e-11 Facial morphology (factor 19); TGCT trans rs10506458 0.915 rs1463821 chr12:63402875 C/G cg03429785 chr15:59498649 MYO1E;LDHAL6B 0.44 7.53 0.56 8.98e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg11003573 chr3:44754125 ZNF502 -0.48 -5.42 -0.44 2.96e-7 Depressive symptoms; TGCT cis rs478222 1.000 rs551573 chr2:25305504 A/G cg01884057 chr2:25150051 NA 0.27 4.95 0.41 2.35e-6 Type 1 diabetes; TGCT cis rs9303401 0.659 rs12952325 chr17:56899371 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.69 6.4 0.5 2.86e-9 Cognitive test performance; TGCT cis rs4746818 0.643 rs2855020 chr10:70856510 C/T cg11621586 chr10:70884670 VPS26A 1.14 7.64 0.57 5.15e-12 Left atrial antero-posterior diameter; TGCT cis rs1577917 1.000 rs2816815 chr6:86691656 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.1 -0.42 1.22e-6 Response to antipsychotic treatment; TGCT cis rs6921919 0.583 rs7764722 chr6:28354533 C/T cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.3 -0.43 5.14e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1799949 1.000 rs11654452 chr17:41189383 G/T cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs950776 0.642 rs12905641 chr15:78964362 A/G cg03762349 chr15:79060523 ADAMTS7 -0.28 -5.59 -0.45 1.38e-7 Sudden cardiac arrest; TGCT cis rs950027 0.787 rs1153845 chr15:45724729 C/T cg14582100 chr15:45693742 SPATA5L1 -0.38 -4.81 -0.4 4.32e-6 Response to fenofibrate (adiponectin levels); TGCT cis rs2742417 1.000 rs2673036 chr3:45752471 C/T cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9640161 0.783 rs35435439 chr7:150063534 C/T cg21361702 chr7:150065534 REPIN1 0.51 4.52 0.38 1.43e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs9611565 0.694 rs5758411 chr22:42079734 G/A cg13695892 chr22:41940480 POLR3H 0.84 8.14 0.59 3.45e-13 Vitiligo; TGCT cis rs3733585 0.673 rs4312757 chr4:9956145 T/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9649213 0.586 rs11768599 chr7:97974555 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.73 -0.62 1.45e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.63e-9 Blood metabolite levels; TGCT cis rs76878669 0.917 rs3116068 chr11:66104993 C/T cg18002602 chr11:66138449 SLC29A2 -0.46 -4.82 -0.4 4.19e-6 Educational attainment (years of education); TGCT cis rs10927875 0.619 rs7537101 chr1:16150384 T/C cg21385522 chr1:16154831 NA -0.76 -9.68 -0.66 7.71e-17 Dilated cardiomyopathy; TGCT cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg20607798 chr8:58055168 NA 0.6 4.9 0.4 2.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg03060546 chr3:49711283 APEH 0.51 4.91 0.4 2.84e-6 Menarche (age at onset); TGCT cis rs35306767 0.903 rs12264711 chr10:929525 T/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg06481639 chr22:41940642 POLR3H 0.74 6.58 0.51 1.2e-9 Vitiligo; TGCT cis rs739496 0.527 rs2097701 chr12:112316774 T/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs2486288 0.656 rs12899058 chr15:45547324 G/A cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs9926296 0.585 rs6500441 chr16:89828669 C/G cg03388025 chr16:89894329 SPIRE2 0.48 7.85 0.58 1.7e-12 Vitiligo; TGCT cis rs3784262 0.669 rs1063666 chr15:58246602 A/C cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.28 -0.49 5.28e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs3821902 0.646 rs17344723 chr3:64019808 G/A cg22134162 chr3:63841271 THOC7 -0.32 -4.77 -0.39 5.15e-6 Breast cancer; TGCT cis rs6952808 0.792 rs34269264 chr7:1948712 C/T cg22963979 chr7:1858916 MAD1L1 -0.35 -5.43 -0.44 2.9e-7 Bipolar disorder and schizophrenia; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg07154950 chr22:24370586 NA -0.21 -4.69 -0.39 6.96e-6 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs4654899 0.802 rs10916903 chr1:21247944 T/C cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs8180040 0.726 rs11130110 chr3:47000606 T/C cg27129171 chr3:47204927 SETD2 0.73 9.4 0.64 3.62e-16 Colorectal cancer; TGCT cis rs6939532 0.522 rs2073528 chr6:26375143 G/C cg05738196 chr6:26577821 NA -0.52 -4.99 -0.41 2.03e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.593 rs2317990 chr8:58024168 G/T cg08280861 chr8:58055591 NA 0.36 5.16 0.42 9.31e-7 Developmental language disorder (linguistic errors); TGCT cis rs7617773 0.817 rs17647717 chr3:48305456 C/T cg11946769 chr3:48343235 NME6 0.76 6.64 0.51 8.76e-10 Coronary artery disease; TGCT cis rs1552244 0.882 rs17050699 chr3:10037167 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs2243480 1.000 rs1964692 chr7:65454183 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs1967977 chr4:98966141 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.19 0.42 8.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2832191 0.716 rs1888439 chr21:30454457 A/G cg24692254 chr21:30365293 RNF160 0.95 11.91 0.73 2.84e-22 Dental caries; TGCT cis rs514406 0.584 rs12095247 chr1:53193796 A/C cg16325326 chr1:53192061 ZYG11B -0.9 -13.25 -0.77 1.67e-25 Monocyte count; TGCT cis rs12541335 0.639 rs4565458 chr8:22154133 T/C cg26039829 chr8:22132926 PIWIL2 0.26 4.74 0.39 5.84e-6 Hypertriglyceridemia; TGCT cis rs4975709 0.589 rs1466606 chr5:1865055 C/T cg15595755 chr5:1867978 NA 0.47 5.52 0.44 1.94e-7 Cardiovascular disease risk factors; TGCT cis rs6424115 0.729 rs1737362 chr1:24054800 T/C cg15997130 chr1:24165203 NA 0.69 6.6 0.51 1.05e-9 Immature fraction of reticulocytes; TGCT cis rs7647973 0.925 rs6808036 chr3:49236439 T/G cg05785598 chr3:49045655 WDR6 0.38 4.68 0.39 7.48e-6 Menarche (age at onset); TGCT cis rs4319547 0.695 rs12314643 chr12:122917423 C/T cg08088222 chr12:122070432 ORAI1 0.26 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs2836974 0.932 rs2836955 chr21:40619887 G/A cg11890956 chr21:40555474 PSMG1 1.04 11.07 0.7 3.18e-20 Cognitive function; TGCT cis rs769267 1.000 rs7246748 chr19:19433105 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs4711350 1.000 rs2395401 chr6:33759471 T/C cg00334056 chr6:33755658 LEMD2 -0.29 -4.56 -0.38 1.22e-5 Schizophrenia; TGCT cis rs7833790 0.926 rs72686467 chr8:82758929 T/G cg27398817 chr8:82754497 SNX16 0.84 5.98 0.47 2.18e-8 Diastolic blood pressure; TGCT cis rs514406 1.000 rs514406 chr1:53330458 A/G cg16325326 chr1:53192061 ZYG11B 0.6 5.1 0.42 1.25e-6 Monocyte count; TGCT cis rs8016982 1.000 rs8016982 chr14:81707057 C/T cg01989461 chr14:81687754 GTF2A1 0.59 4.89 0.4 3.09e-6 Schizophrenia; TGCT cis rs72717009 0.825 rs9427398 chr1:161476205 A/G cg23840854 chr1:161414152 NA -0.98 -5.86 -0.47 3.95e-8 Rheumatoid arthritis; TGCT cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.85 8.69 0.62 1.79e-14 Intelligence (multi-trait analysis); TGCT cis rs7714584 0.826 rs34005003 chr5:150225199 C/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs57920188 0.535 rs58051771 chr1:4092146 T/C cg20703997 chr1:4087676 NA 0.49 5.79 0.46 5.39e-8 Interleukin-17 levels; TGCT cis rs2486288 0.656 rs11639420 chr15:45559268 A/C cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.49 -0.56 1.11e-11 Glomerular filtration rate; TGCT cis rs2153535 0.601 rs1855768 chr6:8472969 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT trans rs6089829 0.962 rs6122347 chr20:61661866 C/T cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1670533 1.000 rs935972 chr4:1045171 A/G cg27284194 chr4:1044797 NA 0.73 5.74 0.46 6.91e-8 Recombination rate (females); TGCT cis rs478304 0.900 rs502468 chr11:65525119 T/G cg17480646 chr11:65405466 SIPA1 0.43 5.38 0.43 3.62e-7 Acne (severe); TGCT cis rs7226408 0.857 rs17652483 chr18:34482270 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.77 0.39 5.08e-6 Obesity-related traits; TGCT cis rs7552404 0.590 rs1565717 chr1:76320441 T/C cg03433033 chr1:76189801 ACADM -0.59 -6.06 -0.48 1.51e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7647973 1.000 rs13088309 chr3:49368317 A/G cg06212747 chr3:49208901 KLHDC8B 0.59 4.72 0.39 6.22e-6 Menarche (age at onset); TGCT cis rs751728 0.965 rs2296743 chr6:33740025 C/T cg13859433 chr6:33739653 LEMD2 -0.4 -7.28 -0.55 3.43e-11 Crohn's disease; TGCT cis rs67073037 0.955 rs6721781 chr2:29120030 G/A cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs7552404 0.960 rs61797339 chr1:76189946 G/T cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9611565 0.681 rs5751094 chr22:41803279 C/T cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT cis rs9611565 0.525 rs1883827 chr22:41703579 A/G cg06634786 chr22:41940651 POLR3H -0.58 -5.28 -0.43 5.62e-7 Vitiligo; TGCT cis rs7072216 0.763 rs6584201 chr10:100170209 T/C cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs7072216 0.763 rs3814140 chr10:100170762 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs6882046 0.513 rs254780 chr5:88019747 G/C cg22951263 chr5:87985283 NA -0.58 -6.18 -0.49 8.49e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6500602 0.627 rs863501 chr16:4588394 G/C cg06139259 chr16:4526053 HMOX2;NMRAL1 -0.26 -4.68 -0.39 7.28e-6 Schizophrenia; TGCT cis rs7829975 0.774 rs1039915 chr8:8679614 T/C cg15556689 chr8:8085844 FLJ10661 0.69 6.17 0.48 8.84e-9 Mood instability; TGCT cis rs7216064 1.000 rs2365468 chr17:65841318 C/T cg12091567 chr17:66097778 LOC651250 -0.84 -6.8 -0.52 4.01e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7666738 0.830 rs10014986 chr4:99000687 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.679 rs7813252 chr8:58136389 C/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs7617773 0.709 rs4404473 chr3:48353626 A/G cg11946769 chr3:48343235 NME6 0.83 7.12 0.54 7.56e-11 Coronary artery disease; TGCT cis rs11874712 0.527 rs7359798 chr18:43648999 A/C cg20479805 chr18:43684716 ATP5A1;HAUS1 -0.44 -4.47 -0.37 1.73e-5 Migraine - clinic-based; TGCT cis rs3020736 0.500 rs6002597 chr22:42488160 C/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.85e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT cis rs7829975 0.564 rs2976855 chr8:8301794 G/A cg15556689 chr8:8085844 FLJ10661 0.69 6.59 0.51 1.11e-9 Mood instability; TGCT cis rs13191362 1.000 rs35044651 chr6:163004142 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.39 6.83 0.52 3.32e-10 Schizophrenia; TGCT cis rs72781680 0.848 rs6748727 chr2:24041058 G/A cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs2066819 1.000 rs2371494 chr12:56728000 G/A cg26714650 chr12:56694279 CS -1.53 -8.28 -0.6 1.67e-13 Psoriasis vulgaris; TGCT cis rs8072100 0.790 rs34200664 chr17:45744652 C/T cg08085267 chr17:45401833 C17orf57 0.46 5.0 0.41 1.91e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7681440 0.904 rs28777703 chr4:90769924 A/G cg14346243 chr4:90757452 SNCA 0.53 5.14 0.42 1.03e-6 Dementia with Lewy bodies; TGCT cis rs36051895 0.632 rs7038813 chr9:5177685 A/G cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.2e-20 Pediatric autoimmune diseases; TGCT cis rs736408 0.716 rs2239549 chr3:52823126 C/T cg07507251 chr3:52567010 NT5DC2 0.45 6.33 0.49 4.06e-9 Bipolar disorder; TGCT cis rs35160687 0.814 rs4392258 chr2:86552577 T/C cg03171300 chr2:86307199 POLR1A -0.27 -4.73 -0.39 6.08e-6 Night sleep phenotypes; TGCT cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6906287 0.647 rs2077162 chr6:118687469 G/A cg21191810 chr6:118973309 C6orf204 0.26 4.46 0.37 1.85e-5 Electrocardiographic conduction measures; TGCT cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg13397359 chr6:42928475 GNMT 0.73 6.82 0.52 3.63e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg15857475 chr8:145742913 RECQL4;LRRC14 -0.79 -8.66 -0.61 2.13e-14 Age at first birth; TGCT cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT cis rs79349575 0.783 rs17708633 chr17:47011620 C/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs7666738 0.830 rs732299 chr4:98995389 C/T cg18180107 chr4:99064573 C4orf37 0.51 4.68 0.39 7.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs797680 0.856 rs7540025 chr1:93759228 C/T cg17826107 chr1:92977322 EVI5 0.23 5.1 0.42 1.24e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2243480 1.000 rs13247184 chr7:65358928 A/G cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg17971929 chr21:40555470 PSMG1 0.95 9.18 0.64 1.22e-15 Cognitive function; TGCT cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg04317338 chr11:64019027 PLCB3 0.78 6.46 0.5 2.17e-9 Mean platelet volume; TGCT cis rs2239547 0.657 rs6445539 chr3:52874296 G/A cg11645453 chr3:52864694 ITIH4 0.35 5.88 0.47 3.57e-8 Schizophrenia; TGCT cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs909674 0.865 rs5757684 chr22:39851584 G/A cg11247378 chr22:39784982 NA -0.71 -8.5 -0.61 5.02e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs6754311 0.593 rs313523 chr2:136432103 G/A cg07169764 chr2:136633963 MCM6 0.65 5.79 0.46 5.38e-8 Mosquito bite size; TGCT cis rs7246657 0.765 rs10402455 chr19:37728707 G/A cg18154014 chr19:37997991 ZNF793 0.91 5.6 0.45 1.33e-7 Coronary artery calcification; TGCT cis rs853679 0.542 rs34131763 chr6:28075000 A/C cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs1513670 1.000 rs1534402 chr17:41809847 C/T cg10758466 chr17:41974087 MPP2 0.27 4.44 0.37 2e-5 Bone mineral density (hip); TGCT cis rs2836974 0.568 rs11910906 chr21:40685662 T/C cg06238570 chr21:40685208 BRWD1 -0.84 -9.31 -0.64 6.01e-16 Cognitive function; TGCT cis rs922182 0.748 rs1380839 chr15:64312164 A/G cg02919090 chr15:64263738 DAPK2 0.25 4.54 0.38 1.29e-5 Blood protein levels; TGCT cis rs1865760 0.713 rs2013063 chr6:25994098 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 6.94 0.53 1.97e-10 Height; TGCT cis rs6952808 1.000 rs6953693 chr7:1886388 C/G cg22963979 chr7:1858916 MAD1L1 -0.34 -5.25 -0.43 6.44e-7 Bipolar disorder and schizophrenia; TGCT cis rs6570726 0.693 rs450921 chr6:145864260 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6964587 0.967 rs10248102 chr7:91699779 G/A cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs9389248 0.690 rs2294321 chr6:135253048 T/G cg24558204 chr6:135376177 HBS1L -0.47 -4.81 -0.4 4.35e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs909341 0.716 rs71325463 chr20:62362834 G/A cg14758556 chr20:62440591 NA 0.3 4.53 0.38 1.38e-5 Atopic dermatitis; TGCT cis rs73001065 0.818 rs16996185 chr19:19720788 G/T cg03709012 chr19:19516395 GATAD2A -1.05 -5.47 -0.44 2.33e-7 LDL cholesterol; TGCT cis rs4129767 0.647 rs1976703 chr17:76401328 C/T cg05887092 chr17:76393375 PGS1 0.22 4.64 0.38 8.75e-6 HDL cholesterol; TGCT cis rs1799949 1.000 rs2298862 chr17:41176688 T/C cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg03609598 chr5:56110824 MAP3K1 -0.59 -4.72 -0.39 6.18e-6 Initial pursuit acceleration; TGCT cis rs9325144 0.560 rs6582561 chr12:38666821 G/A cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs2338224 1.000 rs6888856 chr5:71740716 T/C cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs6964587 1.000 rs12530646 chr7:91588036 A/G cg22709100 chr7:91322751 NA -0.28 -4.72 -0.39 6.31e-6 Breast cancer; TGCT cis rs854765 0.583 rs6502625 chr17:17848286 G/C cg09796270 chr17:17721594 SREBF1 0.26 5.32 0.43 4.72e-7 Total body bone mineral density; TGCT trans rs7726839 0.507 rs60068988 chr5:597668 T/C cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs9653442 0.593 rs6542920 chr2:100845088 A/G cg07810366 chr2:100720526 AFF3 -0.32 -4.51 -0.38 1.46e-5 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs6555056 chr5:226222 T/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs7666738 0.830 rs1405767 chr4:98965295 T/C cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs16867321 0.671 rs10190767 chr2:181475701 G/A cg23363182 chr2:181467187 NA -0.47 -4.93 -0.4 2.56e-6 Obesity; TGCT cis rs9527 0.590 rs1807298 chr10:104870218 G/A cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs12134245 0.776 rs6688261 chr1:91987034 C/T cg07090678 chr1:91966139 CDC7 0.31 4.5 0.37 1.54e-5 Breast cancer; TGCT cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg10263370 chr3:44754102 ZNF502 -0.42 -5.02 -0.41 1.74e-6 Depressive symptoms; TGCT cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg02725872 chr8:58115012 NA -0.39 -4.83 -0.4 3.9e-6 Developmental language disorder (linguistic errors); TGCT cis rs17155006 0.676 rs4730287 chr7:107770624 C/T cg12651599 chr7:107428290 SLC26A3 0.21 4.62 0.38 9.36e-6 Pneumococcal bacteremia; TGCT cis rs1971762 0.545 rs4759280 chr12:54064958 C/A cg16917193 chr12:54089295 NA 1.09 11.22 0.71 1.37e-20 Height; TGCT cis rs9393777 0.513 rs9379893 chr6:26584668 A/G cg15659132 chr6:26577336 NA 0.73 5.32 0.43 4.62e-7 Intelligence (multi-trait analysis); TGCT cis rs1843834 0.539 rs6713629 chr2:225410973 A/T cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs478304 0.651 rs11227281 chr11:65496558 T/C cg27068330 chr11:65405492 SIPA1 -0.94 -9.4 -0.65 3.49e-16 Acne (severe); TGCT cis rs7666738 0.830 rs10011009 chr4:98981749 G/A cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11031096 0.711 rs10767882 chr11:4205841 G/A cg18678763 chr11:4115507 RRM1 -0.45 -5.84 -0.46 4.31e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7819412 0.838 rs3021494 chr8:10983534 A/G cg21775007 chr8:11205619 TDH -0.53 -5.2 -0.42 8.06e-7 Triglycerides; TGCT cis rs7819412 0.511 rs2898290 chr8:11433909 T/C cg21775007 chr8:11205619 TDH -0.54 -5.07 -0.41 1.41e-6 Triglycerides; TGCT cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.716 rs284895 chr15:76751225 C/G cg22467129 chr15:76604101 ETFA 0.53 6.44 0.5 2.39e-9 Blood metabolite levels; TGCT cis rs6598955 0.543 rs3795687 chr1:26560745 G/A cg04990556 chr1:26633338 UBXN11 0.83 8.03 0.59 6.27e-13 Obesity-related traits; TGCT cis rs6912958 0.728 rs7773906 chr6:88251869 T/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs3755132 0.633 rs16862856 chr2:15794281 C/G cg12888861 chr2:15731646 DDX1 0.37 4.55 0.38 1.24e-5 Wilms tumor; TGCT cis rs1008375 0.932 rs10009933 chr4:17670107 A/C cg10189774 chr4:17578691 LAP3 0.51 4.5 0.37 1.54e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9399137 0.507 rs6569986 chr6:135311641 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs7000551 0.689 rs12545909 chr8:22310052 A/G cg12081754 chr8:22256438 SLC39A14 -0.28 -4.54 -0.38 1.33e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1372520 0.748 rs990085 chr4:90754771 A/G cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs250677 1.000 rs40525 chr5:148432932 G/T cg23229984 chr5:148520753 ABLIM3 -0.21 -4.72 -0.39 6.38e-6 Breast cancer; TGCT cis rs2204008 0.658 rs11495742 chr12:38395688 C/A cg13010199 chr12:38710504 ALG10B 0.62 4.79 0.4 4.7e-6 Bladder cancer; TGCT cis rs9911578 0.935 rs420878 chr17:56709077 A/G cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs9911578 0.967 rs8182277 chr17:57144367 C/T cg12560992 chr17:57184187 TRIM37 0.79 9.71 0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs986417 0.901 rs2351172 chr14:61008687 A/G cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs9388451 0.839 rs3799711 chr6:126075313 C/T cg10911889 chr6:126070802 HEY2 -0.51 -5.43 -0.44 2.83e-7 Brugada syndrome; TGCT cis rs727505 0.954 rs989177 chr7:124412886 A/G cg23710748 chr7:124431027 NA -0.27 -4.71 -0.39 6.45e-6 Lewy body disease; TGCT cis rs7113874 0.610 rs1446462 chr11:8566343 C/T cg14521421 chr11:8862019 ST5 0.29 4.68 0.39 7.52e-6 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7772486 0.875 rs1331645 chr6:146398407 C/G cg23711669 chr6:146136114 FBXO30 0.88 9.18 0.64 1.19e-15 Lobe attachment (rater-scored or self-reported); TGCT trans rs561341 0.739 rs1978116 chr17:30220978 A/C cg20587970 chr11:113659929 NA -0.65 -9.08 -0.63 2.05e-15 Hip circumference adjusted for BMI; TGCT cis rs9581857 0.547 rs75085794 chr13:28095944 A/C cg22138327 chr13:27999177 GTF3A 0.72 4.75 0.39 5.45e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7674212 0.539 rs2866635 chr4:104121576 G/A cg16532752 chr4:104119610 CENPE -0.6 -5.46 -0.44 2.51e-7 Type 2 diabetes; TGCT cis rs739496 0.793 rs607316 chr12:111969448 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.38 0.44 3.53e-7 Platelet count; TGCT cis rs763121 0.819 rs5757237 chr22:39073835 G/C cg06022373 chr22:39101656 GTPBP1 0.76 7.43 0.56 1.52e-11 Menopause (age at onset); TGCT cis rs7091068 0.532 rs1018634 chr10:95401292 G/A cg20715218 chr10:95462985 C10orf4 -0.48 -5.81 -0.46 4.88e-8 Urinary tract infection frequency; TGCT cis rs12220238 0.818 rs10824082 chr10:75904080 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7829975 0.633 rs2979181 chr8:8323088 A/T cg06636001 chr8:8085503 FLJ10661 0.79 7.76 0.57 2.65e-12 Mood instability; TGCT cis rs2404602 0.716 rs3866543 chr15:76629609 T/G cg26408565 chr15:76604113 ETFA -0.45 -6.09 -0.48 1.28e-8 Blood metabolite levels; TGCT cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg15691649 chr6:25882328 NA -0.5 -5.61 -0.45 1.24e-7 Intelligence (multi-trait analysis); TGCT cis rs7809950 1.000 rs2520271 chr7:107194949 C/T cg23024343 chr7:107201750 COG5 -0.34 -5.26 -0.43 6.08e-7 Coronary artery disease; TGCT cis rs7715806 0.500 rs77544433 chr5:75001025 C/A cg19683494 chr5:74908142 NA 0.53 4.63 0.38 9.15e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT trans rs1814175 0.645 rs1608632 chr11:49967148 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs7192750 0.562 rs8063403 chr16:71931032 C/T cg06353428 chr16:71660113 MARVELD3 0.8 7.2 0.54 5.05e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs3806933 0.522 rs12522383 chr5:110455266 C/T cg04022379 chr5:110408740 TSLP 0.55 5.88 0.47 3.51e-8 Eosinophilic esophagitis; TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg10150615 chr22:24372951 LOC391322 -0.76 -6.21 -0.49 7.18e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs10507380 0.824 rs117542137 chr13:27904586 T/G cg25543773 chr13:27185723 WASF3 0.31 4.49 0.37 1.6e-5 Electrocardiographic traits; TGCT cis rs1552244 0.882 rs13075842 chr3:10055813 A/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs4622507 0.773 rs12925215 chr16:55049850 T/A cg04853843 chr16:55358461 IRX6 -0.57 -4.94 -0.41 2.45e-6 Social communication problems; TGCT cis rs4383453 0.539 rs4677887 chr3:123100223 A/C cg04890266 chr3:123102914 ADCY5 -0.49 -8.4 -0.6 8.88e-14 Gestational age at birth (maternal effect); TGCT cis rs11958404 0.789 rs7736318 chr5:157477593 A/G cg05962755 chr5:157440814 NA 0.35 4.48 0.37 1.65e-5 IgG glycosylation; TGCT cis rs7914558 1.000 rs7077097 chr10:104945463 G/A cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.65e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7772486 0.754 rs4566902 chr6:146244128 A/G cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9443645 0.901 rs9448590 chr6:79606429 C/G cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs597539 0.552 rs10792006 chr11:68722306 T/C cg06112835 chr11:68658793 MRPL21 -0.34 -6.11 -0.48 1.18e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg06753367 chr22:24256600 NA -0.24 -4.51 -0.38 1.5e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13256369 0.590 rs10113115 chr8:8559588 A/G cg18904891 chr8:8559673 CLDN23 0.54 4.8 0.4 4.46e-6 Obesity-related traits; TGCT cis rs12908161 0.960 rs34452033 chr15:85221993 A/G cg17173187 chr15:85201210 NMB 0.59 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs56104184 0.775 rs73063505 chr19:49402765 T/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg07507251 chr3:52567010 NT5DC2 0.49 7.06 0.54 1.03e-10 Cognitive function; TGCT cis rs11696501 0.688 rs6104295 chr20:44326917 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs858239 0.600 rs59073109 chr7:23133226 C/A cg05602783 chr7:23145260 KLHL7 -0.58 -4.85 -0.4 3.68e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3096299 0.874 rs3102342 chr16:89451575 T/C cg02187348 chr16:89574699 SPG7 0.5 4.84 0.4 3.86e-6 Multiple myeloma (IgH translocation); TGCT cis rs1903068 0.853 rs28838369 chr4:56007249 A/G cg16572876 chr4:56024045 NA 0.46 5.03 0.41 1.65e-6 Endometriosis; TGCT cis rs6714710 0.603 rs12104810 chr2:98443658 C/T cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7582180 0.627 rs6542947 chr2:100999647 C/G cg14675211 chr2:100938903 LONRF2 -0.47 -4.57 -0.38 1.16e-5 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.638 rs12424222 chr12:38548273 C/T cg26384229 chr12:38710491 ALG10B -0.53 -4.77 -0.39 5.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs2153535 0.580 rs7745043 chr6:8513507 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs7226408 0.857 rs55811995 chr18:34622341 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg23758822 chr17:41437982 NA 0.72 6.91 0.53 2.23e-10 Menopause (age at onset); TGCT cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg06238570 chr21:40685208 BRWD1 -0.62 -6.17 -0.48 8.82e-9 Menarche (age at onset); TGCT cis rs9325144 0.647 rs10875953 chr12:39050536 G/C cg10518543 chr12:38710700 ALG10B -0.48 -4.49 -0.37 1.58e-5 Morning vs. evening chronotype; TGCT cis rs9858542 0.953 rs7646366 chr3:49470668 G/A cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2692947 0.673 rs2692894 chr2:96784934 T/G cg22654517 chr2:96458247 NA -0.22 -4.72 -0.39 6.17e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs13008689 0.875 rs55776708 chr2:8520167 A/C cg26785157 chr2:7987059 NA -0.21 -4.5 -0.37 1.56e-5 Longevity; TGCT cis rs6815814 0.950 rs9306967 chr4:38807911 G/C cg02016764 chr4:38805732 TLR1 -0.31 -5.15 -0.42 9.95e-7 Breast cancer; TGCT cis rs17122693 0.551 rs2934681 chr14:51061491 C/T cg04730355 chr14:51134070 SAV1 1.19 12.02 0.73 1.56e-22 Cognitive performance; TGCT cis rs7178572 0.633 rs11857860 chr15:77839761 T/C cg22256960 chr15:77711686 NA -0.81 -7.57 -0.56 7.27e-12 Type 2 diabetes; TGCT cis rs7772486 0.686 rs9399564 chr6:146078907 C/T cg13319975 chr6:146136371 FBXO30 0.5 4.51 0.38 1.46e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs5750830 0.645 rs4821890 chr22:39777523 G/A cg24399712 chr22:39784796 NA -0.98 -12.63 -0.75 5.18e-24 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs80033912 0.626 rs71324982 chr3:49669948 G/A cg03060546 chr3:49711283 APEH 0.71 6.72 0.52 5.8e-10 Intelligence (multi-trait analysis); TGCT cis rs2797160 1.000 rs6933471 chr6:126017029 T/G cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs6867032 0.958 rs4246754 chr5:2014776 A/C cg26168224 chr5:2018326 NA 0.46 8.31 0.6 1.44e-13 Gut microbiome composition (winter); TGCT cis rs2235642 0.928 rs1057610 chr16:1605537 T/C cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.74 -0.39 5.81e-6 Coronary artery disease; TGCT cis rs739496 0.652 rs10849974 chr12:112264158 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs6693567 0.565 rs11205370 chr1:150397567 A/G cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs7095607 0.813 rs10823148 chr10:69926334 C/G cg18986048 chr10:69913749 MYPN 0.45 5.25 0.43 6.44e-7 Lung function (FVC); TGCT cis rs6714788 0.565 rs7599083 chr2:100658077 G/A cg07810366 chr2:100720526 AFF3 -0.35 -5.04 -0.41 1.59e-6 Intelligence (multi-trait analysis); TGCT cis rs2458413 0.563 rs2458419 chr8:105337141 G/C cg23108931 chr8:105342351 NA -0.35 -6.15 -0.48 9.76e-9 Paget's disease; TGCT cis rs9640161 0.783 rs35435439 chr7:150063534 C/T cg10018233 chr7:150070692 REPIN1 0.34 4.92 0.4 2.7e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs116095464 0.558 rs56127718 chr5:270273 G/T cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs7635838 0.620 rs1666988 chr3:11284950 A/G cg00170343 chr3:11313890 ATG7 0.68 6.48 0.5 1.97e-9 HDL cholesterol; TGCT cis rs12220238 0.722 rs6480748 chr10:76421529 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.61 4.76 0.39 5.23e-6 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9311474 0.607 rs4234633 chr3:52557038 C/T cg10802521 chr3:52805072 NEK4 -0.73 -8.95 -0.63 4.39e-15 Electroencephalogram traits; TGCT cis rs1799949 1.000 rs1824889 chr17:41421876 C/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs9393692 0.846 rs7771202 chr6:26279907 A/G cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.14e-9 Educational attainment; TGCT cis rs7582180 0.607 rs1530029 chr2:100968205 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.76 0.39 5.35e-6 Intelligence (multi-trait analysis); TGCT cis rs6922617 0.786 rs4141937 chr6:41341253 G/T cg07798131 chr6:41471673 NA 0.98 4.85 0.4 3.6e-6 Alzheimer's disease biomarkers; TGCT cis rs11190604 1.000 rs2495734 chr10:102338686 G/A cg16342193 chr10:102329863 NA -0.43 -5.39 -0.44 3.43e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs561341 0.709 rs11542477 chr17:30185892 A/G cg20587970 chr11:113659929 NA 0.85 8.5 0.61 5.13e-14 Hip circumference adjusted for BMI; TGCT cis rs3008870 1.000 rs2815370 chr1:67503727 A/G cg08660285 chr1:67390436 MIER1;WDR78 -1.02 -10.78 -0.7 1.65e-19 Lymphocyte percentage of white cells; TGCT cis rs17102423 0.685 rs4899161 chr14:65540901 G/A cg11161011 chr14:65562177 MAX -0.51 -7.28 -0.55 3.3e-11 Obesity-related traits; TGCT cis rs2692947 0.702 rs7604842 chr2:96777340 C/T cg23100626 chr2:96804247 ASTL -0.4 -4.63 -0.38 9.19e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10883723 0.810 rs2296588 chr10:104248087 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4081724 0.565 rs59527310 chr19:33798393 C/T cg18823272 chr19:34111733 CHST8 0.41 4.8 0.4 4.56e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6681544 0.721 rs9438719 chr1:82425063 A/G cg04226724 chr1:82268649 LPHN2 -0.48 -4.95 -0.41 2.42e-6 Metabolite levels (X-11787); TGCT cis rs483180 0.531 rs662243 chr1:120209564 A/C cg19096424 chr1:120255104 PHGDH 0.57 5.33 0.43 4.39e-7 Macular telangiectasia type 2; TGCT cis rs9399135 0.660 rs4267967 chr6:135272477 T/G cg24558204 chr6:135376177 HBS1L 0.51 5.41 0.44 3.13e-7 Red blood cell count; TGCT cis rs10876993 0.928 rs7136269 chr12:58075937 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.83 -0.46 4.52e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs514406 0.861 rs2477741 chr1:53265278 A/G cg01802117 chr1:53393560 SCP2 0.41 4.84 0.4 3.79e-6 Monocyte count; TGCT cis rs11783469 0.522 rs13281304 chr8:23266922 T/C cg00472375 chr8:23315376 ENTPD4 0.67 5.31 0.43 4.94e-7 Reticulocyte count; TGCT cis rs12477438 0.520 rs6712704 chr2:99719687 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs1801251 0.711 rs2592117 chr2:233735693 C/T cg08000102 chr2:233561755 GIGYF2 -0.44 -4.45 -0.37 1.87e-5 Coronary artery disease; TGCT cis rs4372836 0.664 rs4233729 chr2:29092679 T/C cg09522027 chr2:28974177 PPP1CB 0.68 7.1 0.54 8.73e-11 Body mass index; TGCT cis rs9303401 0.659 rs9303399 chr17:56672309 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.84 0.46 4.39e-8 Cognitive test performance; TGCT cis rs1062177 0.756 rs2964587 chr5:151119972 C/T cg00977110 chr5:151150581 G3BP1 -0.4 -4.67 -0.39 7.7e-6 Preschool internalizing problems; TGCT cis rs9341808 0.718 rs1324123 chr6:80932894 G/A cg08355045 chr6:80787529 NA 0.31 5.4 0.44 3.2e-7 Sitting height ratio; TGCT cis rs1475911 1.000 rs17114359 chr21:43510437 A/C cg24372256 chr21:43528868 UMODL1;C21orf128 -0.25 -4.74 -0.39 5.69e-6 IgG glycosylation; TGCT cis rs7659604 0.540 rs28672860 chr4:122705051 G/A cg19748678 chr4:122722346 EXOSC9 -0.58 -5.55 -0.45 1.64e-7 Type 2 diabetes; TGCT cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg11494091 chr17:61959527 GH2 0.43 7.51 0.56 9.88e-12 Height; TGCT cis rs13242816 1.000 rs62471184 chr7:116090300 G/A cg16553024 chr7:116138462 CAV2 -0.46 -5.18 -0.42 8.58e-7 P wave duration; TGCT trans rs8073060 0.586 rs225278 chr17:33974170 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs992157 0.764 rs10932774 chr2:219191569 A/G cg00012203 chr2:219082015 ARPC2 0.71 6.54 0.51 1.44e-9 Colorectal cancer; TGCT cis rs2842992 0.830 rs2273819 chr6:160183325 G/C cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT trans rs66573146 1.000 rs66712119 chr4:6965428 A/T cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs10514758 0.744 rs1949122 chr3:114923069 A/G cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs2658782 0.901 rs7116173 chr11:93222311 C/T cg18152523 chr11:93063302 CCDC67 0.69 5.63 0.45 1.17e-7 Pulmonary function decline; TGCT cis rs7829975 0.742 rs7832968 chr8:8652889 G/A cg08975724 chr8:8085496 FLJ10661 0.58 5.18 0.42 8.76e-7 Mood instability; TGCT cis rs13242816 1.000 rs62471202 chr7:116112562 G/A cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs6964587 1.000 rs926192 chr7:91671853 C/A cg17063962 chr7:91808500 NA 0.88 9.63 0.65 9.8e-17 Breast cancer; TGCT cis rs617219 0.726 rs72764969 chr5:78451409 A/G cg23987322 chr5:78407566 BHMT 0.36 4.67 0.39 7.58e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT trans rs4332037 0.586 rs62442944 chr7:2015047 T/G cg10840412 chr1:235813424 GNG4 0.93 6.69 0.51 6.97e-10 Bipolar disorder; TGCT cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs68170813 0.617 rs117884147 chr7:107177593 T/C cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.32 -5.13 -0.42 1.11e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17345786 0.511 rs1138818 chr3:101399583 C/G cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11971779 0.715 rs7787398 chr7:139061846 A/G cg07862535 chr7:139043722 LUC7L2 0.71 5.55 0.45 1.63e-7 Diisocyanate-induced asthma; TGCT cis rs11098499 0.820 rs2389885 chr4:120533931 C/T cg09307838 chr4:120376055 NA 0.67 6.32 0.49 4.29e-9 Corneal astigmatism; TGCT cis rs875971 1.000 rs4718343 chr7:65874288 T/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs9682041 0.877 rs9682908 chr3:170072010 C/T cg07589077 chr3:170072950 NA 0.29 5.15 0.42 1e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7552404 0.883 rs11161493 chr1:76206254 T/A cg03433033 chr1:76189801 ACADM 0.82 9.91 0.66 2.05e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.95 -0.53 1.82e-10 Prostate cancer; TGCT cis rs13326165 0.671 rs6794675 chr3:52374889 T/A cg07884673 chr3:53033167 SFMBT1 0.39 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs12477438 0.520 rs13030961 chr2:99799520 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.9 9.33 0.64 5.15e-16 Chronic sinus infection; TGCT cis rs9311474 0.575 rs4434138 chr3:52556890 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.56 0.51 1.29e-9 Electroencephalogram traits; TGCT cis rs911263 0.581 rs12890110 chr14:68781595 C/T cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs10986311 0.832 rs10123514 chr9:127142878 T/C cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -5.07 -0.41 1.38e-6 Vitiligo; TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs13191362 1.000 rs35103567 chr6:163183400 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.12 8.19 0.59 2.72e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs6570726 0.846 rs371186 chr6:145886971 T/C cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2072499 0.868 rs2758600 chr1:156195205 C/T cg06970220 chr1:156163860 SLC25A44 0.74 5.98 0.47 2.22e-8 Testicular germ cell tumor; TGCT cis rs10056811 0.538 rs2035191 chr5:74413713 T/C cg19683494 chr5:74908142 NA 0.68 5.65 0.45 1.05e-7 Coronary artery disease; TGCT cis rs61990749 0.597 rs2032781 chr14:78214875 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs7552404 0.556 rs12124417 chr1:76353294 T/C cg22875332 chr1:76189707 ACADM 0.57 5.8 0.46 5.09e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6671200 1.000 rs76064624 chr1:95661033 A/G cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs709400 0.663 rs11628213 chr14:103952453 A/C cg12935359 chr14:103987150 CKB -0.38 -5.78 -0.46 5.69e-8 Body mass index; TGCT cis rs6424115 0.618 rs10917420 chr1:24062987 C/T cg15997130 chr1:24165203 NA 0.64 6.92 0.53 2.16e-10 Immature fraction of reticulocytes; TGCT cis rs10193935 0.901 rs997288 chr2:42525582 C/G cg27598129 chr2:42591480 NA -0.39 -5.31 -0.43 4.84e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1865760 1.000 rs12209482 chr6:25909229 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs17331151 0.512 rs9637477 chr3:52891426 G/C cg27565382 chr3:53032988 SFMBT1 -0.45 -5.76 -0.46 6.25e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs59107033 0.511 rs62262394 chr3:123105428 C/T cg04890266 chr3:123102914 ADCY5 -0.49 -7.87 -0.58 1.48e-12 Lymphocyte counts; TGCT cis rs2730260 0.537 rs73169246 chr7:158890593 C/T cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs1949733 1.000 rs1880023 chr4:8480831 C/T cg11789530 chr4:8429930 ACOX3 -0.65 -6.04 -0.48 1.68e-8 Response to antineoplastic agents; TGCT cis rs7666738 0.830 rs880472 chr4:98922595 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs992157 0.661 rs17653757 chr2:219109364 G/C cg00012203 chr2:219082015 ARPC2 0.81 9.98 0.67 1.41e-17 Colorectal cancer; TGCT cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg19318889 chr4:1322082 MAEA 0.27 6.62 0.51 9.72e-10 Longevity; TGCT cis rs10936602 0.527 rs6793160 chr3:169535266 A/C cg08193579 chr3:169529701 LRRC34 -0.29 -5.43 -0.44 2.79e-7 Renal cell carcinoma; TGCT cis rs12950390 0.853 rs28589850 chr17:45855713 A/G cg06532163 chr17:45867833 NA 0.34 5.42 0.44 2.94e-7 IgG glycosylation; TGCT cis rs61867294 0.794 rs2007698 chr10:106661383 G/A cg08000847 chr10:105880925 C10orf78 0.56 4.46 0.37 1.82e-5 Schizophrenia; TGCT trans rs7618501 0.602 rs2013208 chr3:50129399 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.87 -9.37 -0.64 4.14e-16 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs116094766 chr4:119729291 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs875971 0.638 rs6460305 chr7:66060408 G/A cg00343986 chr7:65444356 GUSB -0.24 -5.29 -0.43 5.43e-7 Aortic root size; TGCT cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.43 -6.34 -0.49 3.94e-9 Alzheimer's disease; TGCT cis rs709400 0.663 rs7158822 chr14:103887868 C/T cg12935359 chr14:103987150 CKB -0.35 -5.33 -0.43 4.54e-7 Body mass index; TGCT cis rs1008375 1.000 rs2109522 chr4:17658645 T/A cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3015497 0.616 rs3825571 chr14:51052118 A/G cg04730355 chr14:51134070 SAV1 -0.61 -6.01 -0.48 1.88e-8 Mean platelet volume; TGCT cis rs938554 0.612 rs4385059 chr4:9989233 A/G cg11266682 chr4:10021025 SLC2A9 -0.57 -5.06 -0.41 1.47e-6 Blood metabolite levels; TGCT cis rs1075232 1.000 rs12438318 chr15:31680445 G/A cg01030201 chr15:31746330 NA -1.1 -5.4 -0.44 3.27e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs12971120 0.891 rs4891558 chr18:72170359 A/G cg25817165 chr18:72167213 CNDP2 -0.29 -5.07 -0.41 1.44e-6 Refractive error; TGCT cis rs4700695 0.719 rs27079 chr5:65443966 C/T cg21114390 chr5:65439923 SFRS12 -0.84 -7.45 -0.56 1.35e-11 Facial morphology (factor 19); TGCT trans rs9951602 0.512 rs7237214 chr18:76657394 C/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.44 0.75 1.51e-23 Obesity-related traits; TGCT cis rs7312933 0.576 rs11181364 chr12:42567800 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7267979 0.528 rs2387976 chr20:25599560 C/T cg14121845 chr20:25566513 NINL -0.41 -4.48 -0.37 1.7e-5 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1814175 0.781 rs1851872 chr11:50009770 A/G cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs477895 0.653 rs72918475 chr11:63878644 G/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.29 0.49 5.05e-9 Mean platelet volume; TGCT cis rs7959452 0.535 rs10878953 chr12:69674187 A/G cg11871910 chr12:69753446 YEATS4 0.62 6.14 0.48 1.03e-8 Blood protein levels; TGCT trans rs1075232 0.677 rs72714666 chr15:31492226 T/C cg17079325 chr7:130131480 MEST;MESTIT1 0.96 6.67 0.51 7.57e-10 Survival in colorectal cancer (non-distant metastatic); TGCT trans rs629535 0.814 rs62513381 chr8:70110991 T/C cg21567404 chr3:27674614 NA -0.55 -8.64 -0.61 2.37e-14 Dupuytren's disease; TGCT cis rs8017423 0.967 rs8015510 chr14:90729984 C/T cg04374321 chr14:90722782 PSMC1 0.78 7.86 0.58 1.59e-12 Mortality in heart failure; TGCT cis rs6671200 1.000 rs933107 chr1:95672229 C/T cg20701556 chr1:95698924 RWDD3 -0.65 -5.58 -0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs78456975 1.000 rs13429866 chr2:1555211 C/A cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs12900413 0.603 rs2118848 chr15:90302503 T/C cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs12681287 0.547 rs9942793 chr8:87509091 C/T cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs1799949 1.000 rs8077486 chr17:41212805 C/T cg05368731 chr17:41323189 NBR1 0.96 9.32 0.64 5.61e-16 Menopause (age at onset); TGCT cis rs6988636 1.000 rs4377946 chr8:124185887 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs68190844 1 rs68190844 chr17:4568953 CTA/C cg00122941 chr17:4613640 ARRB2 -0.89 -7.56 -0.56 7.65e-12 Eosinophil percentage of white cells; TGCT cis rs12134133 0.927 rs4844589 chr1:207432630 C/A cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT trans rs1005277 0.579 rs2474575 chr10:38387901 C/T cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs7772486 0.875 rs10872583 chr6:146396699 G/T cg13319975 chr6:146136371 FBXO30 0.52 4.61 0.38 9.71e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs155076 0.938 rs536209 chr13:21847714 C/T cg14456004 chr13:21872349 NA -1.34 -11.21 -0.71 1.42e-20 White matter hyperintensity burden; TGCT cis rs10256972 0.524 rs6945202 chr7:1116558 T/C cg16145915 chr7:1198662 ZFAND2A -0.43 -4.78 -0.39 4.82e-6 Longevity;Endometriosis; TGCT cis rs12477438 0.520 rs1453563 chr2:99720267 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT trans rs7819412 1.000 rs7819412 chr8:11045161 A/G cg06636001 chr8:8085503 FLJ10661 0.72 6.74 0.52 5.28e-10 Triglycerides; TGCT cis rs514406 0.505 rs431459 chr1:53183230 T/G cg16325326 chr1:53192061 ZYG11B 0.84 12.01 0.73 1.59e-22 Monocyte count; TGCT cis rs9972944 0.729 rs10083875 chr17:63773303 T/C cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg18252515 chr7:66147081 NA -1.25 -7.75 -0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs909674 0.865 rs5757684 chr22:39851584 G/A cg05872129 chr22:39784769 NA -0.98 -9.64 -0.65 9.22e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg25703541 chr22:24373054 LOC391322 -0.82 -8.48 -0.61 5.5e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1018836 0.828 rs7014967 chr8:91557843 G/T cg16814680 chr8:91681699 NA -0.75 -7.83 -0.58 1.82e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10276381 0.579 rs9648026 chr7:28161983 A/G cg23620719 chr7:28220237 JAZF1 -0.76 -4.67 -0.39 7.73e-6 Crohn's disease; TGCT cis rs55823223 0.564 rs58363746 chr17:73850819 C/T cg10935138 chr17:73851978 WBP2 0.82 7.59 0.56 6.81e-12 Psoriasis; TGCT cis rs6840360 0.615 rs12647462 chr4:152607278 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.15 -0.48 9.82e-9 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.593 rs2089811 chr4:152685171 C/T cg17479576 chr4:152424074 FAM160A1 0.52 5.19 0.42 8.44e-7 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.583 rs12908334 chr15:76581592 C/T cg26408565 chr15:76604113 ETFA -0.46 -6.46 -0.5 2.15e-9 Blood metabolite levels; TGCT cis rs1018836 0.663 rs56784954 chr8:91505094 C/T cg16814680 chr8:91681699 NA -0.84 -8.45 -0.6 6.52e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs8031584 0.958 rs11293 chr15:31234981 G/A cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.28e-6 Huntington's disease progression; TGCT cis rs7833790 0.553 rs9693128 chr8:82706128 A/G cg17211192 chr8:82754475 SNX16 -0.9 -8.84 -0.62 8.03e-15 Diastolic blood pressure; TGCT cis rs1982963 0.951 rs56834750 chr14:52509483 T/C cg10843707 chr14:52510701 NID2 -0.42 -6.42 -0.5 2.69e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6570726 0.791 rs6923074 chr6:145893332 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6854137 0.967 rs10033898 chr4:169734457 A/G cg20607169 chr4:169750834 PALLD -0.23 -5.0 -0.41 1.89e-6 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs11864453 0.713 rs6680 chr16:72146570 T/C cg14768367 chr16:72042858 DHODH 0.51 4.89 0.4 3.11e-6 Fibrinogen levels; TGCT cis rs1348850 0.651 rs4893821 chr2:178229352 A/G cg22681709 chr2:178499509 PDE11A 0.35 4.47 0.37 1.75e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg07507251 chr3:52567010 NT5DC2 0.44 6.06 0.48 1.5e-8 Bipolar disorder; TGCT cis rs7666738 0.830 rs6854703 chr4:98977586 A/T cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg27121462 chr16:89883253 FANCA 0.56 5.18 0.42 8.83e-7 Vitiligo; TGCT cis rs74233809 0.901 rs1004467 chr10:104594507 A/G cg05855489 chr10:104503620 C10orf26 0.81 4.71 0.39 6.44e-6 Birth weight; TGCT cis rs10504229 0.683 rs1495865 chr8:58141160 T/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7027203 0.828 rs10761287 chr9:96609150 A/G cg14396892 chr9:96623032 NA -0.26 -5.46 -0.44 2.51e-7 DNA methylation (variation); TGCT cis rs9788682 0.895 rs3813570 chr15:78832832 T/C cg06917634 chr15:78832804 PSMA4 -0.7 -4.86 -0.4 3.47e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs74417235 0.684 rs12655636 chr5:154057618 T/C cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs6500602 0.702 rs11076835 chr16:4549618 G/A cg08645402 chr16:4508243 NA 0.18 5.19 0.42 8.41e-7 Schizophrenia; TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg16031515 chr1:205743344 RAB7L1 -0.27 -4.56 -0.38 1.2e-5 Menarche (age at onset); TGCT cis rs9527 0.545 rs10218853 chr10:104796787 A/C cg15744005 chr10:104629667 AS3MT -0.41 -4.78 -0.39 4.88e-6 Arsenic metabolism; TGCT cis rs8032315 0.965 rs12906125 chr15:91427612 G/A cg05211768 chr15:91427848 FES 0.49 4.93 0.4 2.57e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs7618501 0.538 rs9856572 chr3:50109073 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.5 -0.65 2.02e-16 Intelligence (multi-trait analysis); TGCT cis rs5769765 0.819 rs9616377 chr22:50310880 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs3806843 0.676 rs2245643 chr5:140029780 C/T cg19875535 chr5:140030758 IK -0.37 -6.44 -0.5 2.4e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs56309584 0.560 rs56346215 chr17:8076917 A/C cg08322244 chr17:8066669 VAMP2 -0.52 -4.89 -0.4 3.04e-6 Initial pursuit acceleration; TGCT cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg11494091 chr17:61959527 GH2 0.6 16.09 0.82 3.89e-32 Prudent dietary pattern; TGCT cis rs2153535 0.580 rs2327058 chr6:8447018 C/T cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs9858542 0.537 rs9873994 chr3:49359943 T/C cg08550065 chr3:50336684 HYAL3;NAT6 0.65 4.53 0.38 1.37e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs4319547 0.695 rs7969429 chr12:122875606 A/G cg05707623 chr12:122985044 ZCCHC8 -0.62 -4.87 -0.4 3.32e-6 Body mass index; TGCT cis rs9790314 1.000 rs9850455 chr3:161017192 G/A cg03342759 chr3:160939853 NMD3 -0.43 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs6570726 0.791 rs378937 chr6:145834745 C/T cg05347473 chr6:146136440 FBXO30 0.5 4.63 0.38 9.18e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs17108533 0.588 rs35594700 chr14:71302415 G/T cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs2120019 1.000 rs12903201 chr15:75370776 A/C cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs892961 0.932 rs3987885 chr17:75414990 A/G cg05865280 chr17:75406074 SEPT9 0.29 6.98 0.53 1.61e-10 Airflow obstruction; TGCT cis rs7208859 0.673 rs11651802 chr17:29159660 T/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7086627 0.515 rs4933390 chr10:82213081 A/C cg01528321 chr10:82214614 TSPAN14 0.69 6.51 0.5 1.71e-9 Post bronchodilator FEV1; TGCT cis rs59197085 0.636 rs3807132 chr7:128469484 T/C cg00260937 chr7:128520193 KCP 0.46 4.82 0.4 4.15e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs4713118 0.662 rs9468277 chr6:28028390 C/A cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs12200560 0.505 rs211167 chr6:97069087 T/A cg06623918 chr6:96969491 KIAA0776 0.57 4.82 0.4 4.04e-6 Coronary heart disease; TGCT cis rs6141769 0.542 rs6057628 chr20:31308684 C/T cg13636640 chr20:31349939 DNMT3B -0.51 -4.86 -0.4 3.45e-6 Subjective well-being; TGCT cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg20276088 chr3:133502917 NA -0.28 -5.9 -0.47 3.28e-8 Iron status biomarkers; TGCT cis rs1371867 0.846 rs1660332 chr8:101309490 A/G cg06636551 chr8:101224915 SPAG1 0.42 5.65 0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs1541995 0.824 rs12899483 chr15:96241595 A/G cg00882281 chr15:96346592 NA 0.3 4.85 0.4 3.7e-6 Photic sneeze reflex; TGCT cis rs2562456 0.917 rs2562468 chr19:21714850 G/A cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs9733 0.596 rs17658705 chr1:150678071 A/C cg04414720 chr1:150670196 GOLPH3L -0.39 -5.04 -0.41 1.58e-6 Tonsillectomy; TGCT cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg21724239 chr8:58056113 NA 0.5 5.78 0.46 5.71e-8 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.520 rs6542870 chr2:99796638 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs9486719 0.857 rs9285393 chr6:97020917 C/A cg06623918 chr6:96969491 KIAA0776 -1.01 -9.38 -0.64 4.08e-16 Migraine;Coronary artery disease; TGCT trans rs877282 0.945 rs10904556 chr10:789429 A/G cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg06634786 chr22:41940651 POLR3H 0.73 6.81 0.52 3.84e-10 Vitiligo; TGCT cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg18654377 chr3:49208889 KLHDC8B -0.38 -5.03 -0.41 1.69e-6 Menarche (age at onset); TGCT cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs916888 0.773 rs199448 chr17:44809001 A/G cg15921436 chr17:44337874 NA 0.56 8.16 0.59 3.13e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2153535 0.580 rs6597318 chr6:8437289 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.24 0.43 6.68e-7 Motion sickness; TGCT cis rs8072100 0.905 rs8077106 chr17:45653291 T/G cg08085267 chr17:45401833 C17orf57 0.47 5.13 0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs28595532 0.920 rs28837152 chr4:119782868 G/A cg00700008 chr4:120138107 USP53 0.49 4.48 0.37 1.71e-5 Cannabis dependence symptom count; TGCT cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg22105103 chr4:187893119 NA 0.33 4.56 0.38 1.22e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs13217239 0.646 rs12527111 chr6:27006475 C/T cg02458000 chr6:26745757 NA 0.5 4.61 0.38 1e-5 Schizophrenia; TGCT cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs1198872 0.503 rs1627163 chr2:10954844 A/G cg15705551 chr2:10952987 PDIA6 0.53 5.04 0.41 1.64e-6 Cardiac Troponin-T levels; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg15242686 chr22:24348715 GSTTP1 0.43 5.95 0.47 2.54e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9906944 0.707 rs8068981 chr17:47122525 T/C cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs17345786 1.000 rs55641278 chr3:101290577 G/A cg12386194 chr3:101231763 SENP7 0.59 5.45 0.44 2.65e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.657 rs10211024 chr2:238353776 A/T cg14458575 chr2:238380390 NA 0.46 7.08 0.54 9.6e-11 Prostate cancer; TGCT cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs9341808 0.621 rs2322627 chr6:80806341 T/A cg08355045 chr6:80787529 NA 0.36 6.41 0.5 2.79e-9 Sitting height ratio; TGCT cis rs11122272 0.766 rs2790867 chr1:231548059 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.71 6.89 0.53 2.5e-10 Hemoglobin concentration; TGCT cis rs7428 0.545 rs2366404 chr2:85551779 G/A cg03728395 chr2:85555865 TGOLN2 -0.29 -4.97 -0.41 2.16e-6 Ear protrusion; TGCT cis rs7681440 0.904 rs17192189 chr4:90774928 A/C cg14346243 chr4:90757452 SNCA 0.5 4.7 0.39 6.86e-6 Dementia with Lewy bodies; TGCT cis rs3733631 1.000 rs7667662 chr4:104590704 A/G cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg01585852 chr22:24235823 MIF 0.22 4.82 0.4 4.16e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7824557 0.544 rs1865521 chr8:11231249 T/C cg21775007 chr8:11205619 TDH 0.65 6.65 0.51 8.38e-10 Retinal vascular caliber; TGCT cis rs7772486 0.686 rs2092263 chr6:146029687 G/A cg23711669 chr6:146136114 FBXO30 -0.88 -9.77 -0.66 4.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs1115078 chr6:8449638 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs875971 0.830 rs1167406 chr7:65556936 G/C cg11764359 chr7:65958608 NA -0.56 -4.82 -0.4 4.1e-6 Aortic root size; TGCT cis rs6815814 0.851 rs5743551 chr4:38807654 T/C cg06935464 chr4:38784597 TLR10 0.29 4.59 0.38 1.08e-5 Breast cancer; TGCT cis rs6570726 0.935 rs387965 chr6:145869366 A/G cg05347473 chr6:146136440 FBXO30 0.5 4.57 0.38 1.17e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs909341 0.537 rs11696871 chr20:62387417 C/T cg14758556 chr20:62440591 NA 0.4 5.74 0.46 6.9e-8 Atopic dermatitis; TGCT cis rs8177253 1.000 rs1358023 chr3:133484393 T/C cg11941060 chr3:133502564 NA -0.29 -6.13 -0.48 1.09e-8 Iron status biomarkers; TGCT cis rs2629540 0.765 rs4962687 chr10:126404141 G/A cg08799069 chr10:126477246 METTL10 -0.29 -4.8 -0.4 4.53e-6 Cocaine dependence; TGCT cis rs9733 0.596 rs12089989 chr1:150715782 G/A cg04414720 chr1:150670196 GOLPH3L 0.36 4.56 0.38 1.21e-5 Tonsillectomy; TGCT cis rs7258465 1.000 rs76194 chr19:18630580 T/G cg06462663 chr19:18546047 ISYNA1 0.22 5.16 0.42 9.61e-7 Breast cancer; TGCT cis rs72945132 0.882 rs6592537 chr11:70172975 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9549367 0.737 rs11619691 chr13:113904636 T/C cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs35306767 0.668 rs35657988 chr10:1103590 A/G cg26597838 chr10:835615 NA 0.46 5.08 0.41 1.37e-6 Eosinophil percentage of granulocytes; TGCT cis rs6991838 0.593 rs7011464 chr8:66635287 A/T cg19143639 chr8:66472813 NA -0.36 -4.45 -0.37 1.87e-5 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs904251 0.523 rs2776871 chr6:37481759 A/G cg25019722 chr6:37503610 NA -0.53 -8.19 -0.59 2.75e-13 Cognitive performance; TGCT cis rs6788895 0.661 rs73010956 chr3:150492724 A/G cg07663535 chr3:150480033 SIAH2 0.96 4.49 0.37 1.6e-5 Breast cancer; TGCT cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9503598 0.778 rs1328688 chr6:3468508 G/A cg00476032 chr6:3446245 SLC22A23 0.17 4.99 0.41 2.03e-6 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); TGCT cis rs9527 0.590 rs1475642 chr10:104546183 C/T cg15744005 chr10:104629667 AS3MT 0.5 5.6 0.45 1.34e-7 Arsenic metabolism; TGCT trans rs78661745 0.764 rs77416036 chr3:163924516 G/A cg25373553 chr5:151328029 NA 0.47 6.64 0.51 8.64e-10 Bulimia nervosa; TGCT cis rs4237845 0.715 rs4760340 chr12:58275176 A/T cg16577509 chr12:58013651 SLC26A10 -0.43 -4.67 -0.39 7.72e-6 Intelligence (multi-trait analysis); TGCT cis rs1878931 0.582 rs27225 chr16:3428060 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.41 -0.5 2.7e-9 Body mass index (adult); TGCT cis rs7666738 0.830 rs4699600 chr4:99019429 C/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1857353 1.000 rs17096865 chr1:75894676 T/G cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs56309584 0.560 rs11655996 chr17:8094753 A/C cg08322244 chr17:8066669 VAMP2 -0.56 -5.42 -0.44 3e-7 Initial pursuit acceleration; TGCT cis rs861020 1.000 rs632746 chr1:209982515 C/T cg05527609 chr1:210001259 C1orf107 0.91 7.4 0.55 1.84e-11 Orofacial clefts; TGCT cis rs10504229 0.683 rs10504223 chr8:58140944 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs10465746 0.905 rs12738214 chr1:84359050 C/A cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs739496 0.602 rs79209359 chr12:111967161 A/T cg10833066 chr12:111807467 FAM109A 0.37 5.16 0.42 9.31e-7 Platelet count; TGCT cis rs8077889 0.917 rs72836553 chr17:41909851 A/G cg26893861 chr17:41843967 DUSP3 1.08 12.97 0.76 7.86e-25 Triglycerides; TGCT trans rs10504390 0.656 rs74776773 chr8:66544150 G/A cg18118147 chr19:51128640 SYT3 -0.77 -6.85 -0.52 2.99e-10 IgG glycosylation; TGCT cis rs11098499 0.754 rs10212775 chr4:120239244 G/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs7659604 0.539 rs11098646 chr4:122729301 T/C cg19748678 chr4:122722346 EXOSC9 0.9 9.34 0.64 4.9e-16 Type 2 diabetes; TGCT cis rs10131894 0.611 rs175001 chr14:75436452 A/C cg08847533 chr14:75593920 NEK9 0.63 5.73 0.46 7.2e-8 Coronary artery disease; TGCT cis rs60843830 1.000 rs17713729 chr2:249092 A/C cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.7 0.57 3.68e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs13256369 0.802 rs35382339 chr8:8559255 G/A cg18904891 chr8:8559673 CLDN23 0.57 5.04 0.41 1.6e-6 Obesity-related traits; TGCT cis rs7829975 0.774 rs57312668 chr8:8680477 G/A cg15556689 chr8:8085844 FLJ10661 0.69 6.17 0.48 8.84e-9 Mood instability; TGCT cis rs4862750 0.519 rs10049830 chr4:187861593 T/C cg10295955 chr4:187884368 NA 0.55 5.54 0.45 1.72e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6542838 0.554 rs4311103 chr2:99538362 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.32 -0.43 4.74e-7 Fear of minor pain; TGCT cis rs9677476 0.909 rs13428369 chr2:232125632 T/C cg07929768 chr2:232055508 NA 0.3 4.48 0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs709400 0.663 rs11624367 chr14:103892818 T/A cg12935359 chr14:103987150 CKB -0.34 -4.9 -0.4 2.95e-6 Body mass index; TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg08736216 chr1:53307985 ZYG11A -0.25 -4.68 -0.39 7.33e-6 Monocyte count; TGCT cis rs4780401 0.609 rs4781141 chr16:11808769 A/C cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs17376456 1.000 rs10514382 chr5:93566534 G/A cg25358565 chr5:93447407 FAM172A 0.93 6.39 0.5 3.1e-9 Diabetic retinopathy; TGCT cis rs6964587 0.967 rs55801687 chr7:91762629 C/A cg17063962 chr7:91808500 NA 0.89 9.51 0.65 1.9e-16 Breast cancer; TGCT cis rs11690935 0.959 rs10194102 chr2:172626143 G/C cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT trans rs61931739 0.500 rs7489270 chr12:34432062 C/T cg26384229 chr12:38710491 ALG10B 0.73 6.93 0.53 2.06e-10 Morning vs. evening chronotype; TGCT cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg07061783 chr6:25882402 NA -0.58 -5.47 -0.44 2.41e-7 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg03609598 chr5:56110824 MAP3K1 -0.57 -4.57 -0.38 1.15e-5 Initial pursuit acceleration; TGCT cis rs4820539 0.934 rs3788351 chr22:23469181 T/C cg21100191 chr22:23484243 RTDR1 0.84 9.39 0.64 3.73e-16 Bone mineral density; TGCT cis rs9911578 1.000 rs7342903 chr17:56914588 C/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs28887893 chr4:98963006 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs7523273 0.597 rs2724374 chr1:207941191 G/T cg22525895 chr1:207977042 MIR29B2 0.46 6.74 0.52 5.2400000000000005e-10 Schizophrenia; TGCT cis rs80282103 0.618 rs11818314 chr10:1148157 G/C cg18964960 chr10:1102726 WDR37 0.98 4.57 0.38 1.15e-5 Glomerular filtration rate (creatinine); TGCT cis rs6860806 0.631 rs4705931 chr5:131588345 T/C cg24060327 chr5:131705240 SLC22A5 -0.59 -5.9 -0.47 3.16e-8 Breast cancer; TGCT trans rs8073060 0.586 rs8074800 chr17:33979148 A/G cg19694781 chr19:47549865 TMEM160 0.55 12.98 0.76 7.31e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg24549020 chr5:56110836 MAP3K1 0.66 5.79 0.46 5.56e-8 Initial pursuit acceleration; TGCT cis rs9921338 0.961 rs8043692 chr16:11426957 C/T cg00044050 chr16:11439710 C16orf75 -0.91 -7.07 -0.54 1.01e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg26338869 chr17:61819248 STRADA -0.55 -4.99 -0.41 1.98e-6 Prudent dietary pattern; TGCT cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg15691649 chr6:25882328 NA -0.4 -4.65 -0.39 8.35e-6 Intelligence (multi-trait analysis); TGCT cis rs1577917 1.000 rs884841 chr6:86680300 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.12 -0.42 1.11e-6 Response to antipsychotic treatment; TGCT cis rs3008870 0.755 rs2815365 chr1:67499628 C/T cg11518657 chr1:67396239 MIER1 0.47 4.61 0.38 9.68e-6 Lymphocyte percentage of white cells; TGCT cis rs6840360 0.541 rs4696251 chr4:152266326 T/C cg17479576 chr4:152424074 FAM160A1 -0.45 -4.77 -0.39 5.1e-6 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.825 rs56108532 chr5:93276342 C/T cg25358565 chr5:93447407 FAM172A 0.98 7.89 0.58 1.35e-12 Diabetic retinopathy; TGCT cis rs13326165 0.715 rs66462821 chr3:52390555 C/T cg07884673 chr3:53033167 SFMBT1 0.39 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7772486 0.875 rs2328712 chr6:146344563 T/C cg05347473 chr6:146136440 FBXO30 0.5 4.73 0.39 6.03e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7312933 0.567 rs11181399 chr12:42666412 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 5.1 0.42 1.26e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9811920 0.609 rs6765027 chr3:99687730 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.56 0.51 1.34e-9 Axial length; TGCT trans rs66573146 1.000 rs59683609 chr4:6964910 C/G cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs13256369 1.000 rs873064 chr8:8572380 G/A cg17143192 chr8:8559678 CLDN23 0.62 5.83 0.46 4.57e-8 Obesity-related traits; TGCT cis rs7267979 1.000 rs7268053 chr20:25328286 A/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9788682 0.747 rs7183604 chr15:78899213 T/C cg24631222 chr15:78858424 CHRNA5 -0.88 -6.66 -0.51 7.79e-10 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7010267 0.773 rs4876869 chr8:119941277 A/G cg17171407 chr8:119960777 TNFRSF11B -0.28 -4.97 -0.41 2.17e-6 Total body bone mineral density (age 45-60); TGCT cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg07507251 chr3:52567010 NT5DC2 -0.48 -6.71 -0.52 6.19e-10 Bipolar disorder; TGCT trans rs4650994 0.525 rs2493848 chr1:178547838 T/A cg05059571 chr16:84539110 KIAA1609 0.53 10.64 0.69 3.57e-19 HDL cholesterol levels;HDL cholesterol; TGCT trans rs7864133 1.000 rs11139252 chr9:84063562 T/C cg23451063 chr7:1059876 C7orf50 0.55 6.93 0.53 2.02e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs28595532 0.920 rs56331118 chr4:119767054 G/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg19536664 chr17:6899085 ALOX12 -0.36 -5.83 -0.46 4.47e-8 Tonsillectomy; TGCT cis rs2710642 0.678 rs11125946 chr2:63298150 C/T cg17519650 chr2:63277830 OTX1 -0.61 -5.62 -0.45 1.22e-7 LDL cholesterol levels;LDL cholesterol; TGCT cis rs1784581 0.588 rs1789986 chr6:162409978 C/T cg17173639 chr6:162384350 PARK2 -0.39 -6.58 -0.51 1.19e-9 Itch intensity from mosquito bite; TGCT trans rs1828853 1.000 rs4343046 chr11:82106739 G/T cg22704057 chr2:74425085 MTHFD2 0.55 6.68 0.51 7.27e-10 Curve progression in adolescent idiopathic scoliosis; TGCT cis rs807669 0.903 rs762527 chr22:19183470 A/G cg02655711 chr22:19163373 SLC25A1 0.42 9.92 0.67 1.94e-17 Metabolite levels; TGCT cis rs12682352 0.602 rs6993494 chr8:8667444 C/T cg15556689 chr8:8085844 FLJ10661 0.59 5.03 0.41 1.69e-6 Neuroticism; TGCT cis rs35146811 0.695 rs1623264 chr7:99811204 G/C cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg02953382 chr22:24373134 LOC391322 -0.76 -6.15 -0.48 9.88e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs539096 0.831 rs10789436 chr1:44040966 T/G cg12908607 chr1:44402522 ARTN -0.51 -5.32 -0.43 4.61e-7 Intelligence (multi-trait analysis); TGCT cis rs4499344 0.576 rs259280 chr19:33161452 C/T cg26639809 chr19:33781782 NA 0.22 4.46 0.37 1.8e-5 Mean platelet volume; TGCT cis rs9486719 1.000 rs2499816 chr6:96878206 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs6542838 0.641 rs12712042 chr2:99534401 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.32 -0.43 4.61e-7 Fear of minor pain; TGCT cis rs13242816 1.000 rs35515812 chr7:116156032 C/G cg02799643 chr7:116139180 CAV2 -0.44 -5.54 -0.45 1.74e-7 P wave duration; TGCT cis rs453301 0.686 rs2409120 chr8:8882571 G/C cg00184457 chr8:8946301 NA -0.26 -4.83 -0.4 3.98e-6 Joint mobility (Beighton score); TGCT cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg13695892 chr22:41940480 POLR3H -0.92 -9.33 -0.64 5.22e-16 Vitiligo; TGCT cis rs78456975 1.000 rs11884854 chr2:1566154 A/G cg01028140 chr2:1542097 TPO -0.33 -4.54 -0.38 1.29e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg16145915 chr7:1198662 ZFAND2A -0.57 -7.2 -0.54 5.16e-11 Longevity;Endometriosis; TGCT cis rs12765878 0.580 rs67764572 chr10:105596007 T/C cg11005552 chr10:105648138 OBFC1 -0.39 -6.05 -0.48 1.58e-8 Coronary artery disease; TGCT cis rs7666738 0.830 rs62321570 chr4:98984276 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs734999 0.566 rs10752747 chr1:2524915 G/T cg18854424 chr1:2615690 NA 0.46 5.23 0.43 6.92e-7 Ulcerative colitis; TGCT cis rs7424096 0.613 rs72873859 chr2:37246738 T/G cg14987922 chr2:37194071 STRN 0.53 4.81 0.4 4.29e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs11098499 0.644 rs2389880 chr4:120559870 T/A cg09307838 chr4:120376055 NA 0.63 5.79 0.46 5.56e-8 Corneal astigmatism; TGCT cis rs3091242 0.933 rs34006994 chr1:25780668 C/T cg10117171 chr1:25599238 RHD 0.3 4.92 0.4 2.69e-6 Erythrocyte sedimentation rate; TGCT cis rs1670533 0.929 rs6599280 chr4:1063818 A/G cg27284194 chr4:1044797 NA 0.69 5.99 0.47 2.14e-8 Recombination rate (females); TGCT cis rs4713118 0.587 rs9393899 chr6:28133528 G/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Parkinson's disease; TGCT cis rs10871290 0.650 rs28484753 chr16:74489395 G/C cg01733217 chr16:74700730 RFWD3 0.56 4.68 0.39 7.37e-6 Breast cancer; TGCT cis rs2204008 0.744 rs11514358 chr12:38255526 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs13242816 1.000 rs3801993 chr7:116190382 C/G cg16553024 chr7:116138462 CAV2 -0.45 -5.3 -0.43 5.1e-7 P wave duration; TGCT cis rs4319547 0.695 rs10773152 chr12:122910180 T/C cg05707623 chr12:122985044 ZCCHC8 -0.65 -5.07 -0.41 1.39e-6 Body mass index; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg24846343 chr22:24311635 DDTL 0.23 5.88 0.47 3.59e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13315871 1.000 rs11706420 chr3:58392411 C/T cg12435725 chr3:58293450 RPP14 0.43 4.47 0.37 1.71e-5 Cholesterol, total; TGCT cis rs3008870 0.959 rs2815359 chr1:67494374 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.4 0.72 5.07e-21 Lymphocyte percentage of white cells; TGCT cis rs11642862 1.000 rs74483355 chr16:30836430 C/T cg02466173 chr16:30829666 NA -0.38 -4.48 -0.37 1.69e-5 Tonsillectomy; TGCT cis rs7635838 0.859 rs6779840 chr3:11425423 A/G cg00170343 chr3:11313890 ATG7 0.63 5.93 0.47 2.82e-8 HDL cholesterol; TGCT cis rs12477438 0.520 rs11123762 chr2:99727789 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs35306767 0.668 rs12784928 chr10:1083617 A/C cg20503657 chr10:835505 NA 0.44 4.99 0.41 1.96e-6 Eosinophil percentage of granulocytes; TGCT cis rs2197308 0.765 rs11182992 chr12:37935572 G/C cg26384229 chr12:38710491 ALG10B 0.87 7.83 0.58 1.85e-12 Morning vs. evening chronotype; TGCT cis rs28602288 1 rs28602288 chr19:41388740 C/T cg17435250 chr19:41386441 CYP2A7 -0.51 -5.01 -0.41 1.82e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); TGCT cis rs2153535 0.580 rs1119688 chr6:8460850 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs12681287 0.640 rs7816275 chr8:87373404 A/G cg27223183 chr8:87520930 FAM82B 0.9 6.71 0.52 6.12e-10 Caudate activity during reward; TGCT cis rs9952991 0.943 rs9952753 chr18:12780463 A/C cg23598886 chr18:12777645 NA 0.62 5.78 0.46 5.63e-8 Inflammatory skin disease; TGCT cis rs6570726 0.846 rs453834 chr6:145886261 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6988636 1.000 rs16898088 chr8:124190501 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs76935404 0.868 rs73034462 chr19:41418134 G/A cg19493303 chr19:41414353 NA 0.42 5.05 0.41 1.53e-6 nicotine metabolite ratio in current smokers; TGCT cis rs9733 0.525 rs11584184 chr1:150695689 A/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs9325144 0.647 rs12822023 chr12:39097964 T/C cg26384229 chr12:38710491 ALG10B -0.55 -5.16 -0.42 9.52e-7 Morning vs. evening chronotype; TGCT cis rs7524258 0.868 rs1304712 chr1:7270538 C/T cg07173049 chr1:7289937 CAMTA1 0.3 4.99 0.41 1.97e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7666738 0.716 rs13108535 chr4:99046324 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs59197085 0.636 rs61012549 chr7:128442897 G/A cg00260937 chr7:128520193 KCP 0.49 5.06 0.41 1.46e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs624899 1.000 rs624899 chr19:11612498 C/T cg01045132 chr19:11649571 CNN1 0.47 4.63 0.38 9.12e-6 Presence of antiphospholipid antibodies; TGCT cis rs4654899 0.758 rs6668370 chr1:21369568 C/T cg01072550 chr1:21505969 NA -0.57 -9.34 -0.64 4.93e-16 Superior frontal gyrus grey matter volume; TGCT cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg17345569 chr6:42928274 GNMT -0.48 -4.97 -0.41 2.22e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10114408 0.959 rs10124041 chr9:96652394 T/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs13191362 1.000 rs34655790 chr6:163202739 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.76 0.52 4.71e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9486719 1.000 rs4077932 chr6:96905144 C/T cg18709589 chr6:96969512 KIAA0776 -0.68 -5.05 -0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs7095607 0.813 rs7895717 chr10:69924100 A/G cg18986048 chr10:69913749 MYPN 0.49 5.79 0.46 5.36e-8 Lung function (FVC); TGCT cis rs17376456 0.825 rs36042718 chr5:93180997 C/T cg25358565 chr5:93447407 FAM172A 0.98 7.67 0.57 4.38e-12 Diabetic retinopathy; TGCT cis rs4455778 0.659 rs13226394 chr7:49026826 T/C cg26309511 chr7:48887640 NA -0.45 -5.27 -0.43 5.77e-7 Lung cancer in never smokers; TGCT cis rs35934224 0.783 rs12159647 chr22:19860575 C/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.04e-7 Glaucoma (primary open-angle); TGCT cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs727563 0.520 rs132773 chr22:42031768 T/A cg13695892 chr22:41940480 POLR3H 0.86 8.2 0.59 2.63e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1403694 0.669 rs10440056 chr3:186433822 C/T cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs7611238 0.560 rs7650623 chr3:195088672 C/T cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs4819052 0.851 rs2838837 chr21:46665988 C/T cg06618935 chr21:46677482 NA -0.37 -5.64 -0.45 1.1e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.83 -0.4 3.91e-6 Prudent dietary pattern; TGCT cis rs13064411 0.542 rs2087130 chr3:113226983 T/A cg18753928 chr3:113234510 CCDC52 -0.56 -4.72 -0.39 6.3e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs902774 0.597 rs7299694 chr12:53352572 A/C cg16329197 chr12:53359506 NA -0.5 -7.06 -0.54 1.04e-10 Prostate cancer; TGCT cis rs595982 0.527 rs12151238 chr19:49368613 T/C cg17863274 chr19:49399704 TULP2 -0.47 -6.78 -0.52 4.43e-10 Red cell distribution width; TGCT cis rs4654899 0.802 rs9651021 chr1:21222770 A/C cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs2050392 0.767 rs2183175 chr10:30699336 A/G cg18806716 chr10:30721971 MAP3K8 0.66 8.87 0.62 6.6e-15 Inflammatory bowel disease; TGCT cis rs2795502 0.873 rs3121327 chr10:43388285 G/A cg20628663 chr10:43360327 NA 0.36 5.51 0.44 1.96e-7 Blood protein levels; TGCT cis rs4786125 0.587 rs6500861 chr16:6923966 A/G cg03623568 chr16:6915990 A2BP1 -0.45 -6.77 -0.52 4.65e-10 Heart rate variability traits (SDNN); TGCT cis rs17741873 0.779 rs10824037 chr10:75588878 G/A cg07699608 chr10:75541558 CHCHD1 0.73 5.14 0.42 1.03e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs904251 0.523 rs2776872 chr6:37482787 C/G cg08126542 chr6:37504118 NA -0.43 -6.28 -0.49 5.34e-9 Cognitive performance; TGCT cis rs2153535 0.580 rs1932280 chr6:8473654 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs12711979 0.765 rs7559345 chr2:3818523 G/A cg17052675 chr2:3827356 NA -0.4 -7.89 -0.58 1.34e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs1008375 1.000 rs917665 chr4:17668504 A/C cg18681998 chr4:17616180 MED28 -0.88 -9.73 -0.66 5.62e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2242116 0.932 rs4683301 chr3:46931478 A/T cg27129171 chr3:47204927 SETD2 -0.59 -6.16 -0.48 9.25e-9 Birth weight; TGCT cis rs909674 0.775 rs8138462 chr22:39839670 G/C cg24399712 chr22:39784796 NA -1.05 -11.41 -0.72 4.79e-21 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4975709 0.589 rs1466607 chr5:1864856 A/G cg04156016 chr5:1868137 NA 0.34 5.08 0.41 1.36e-6 Cardiovascular disease risk factors; TGCT cis rs7818688 0.697 rs17665714 chr8:95982542 T/C cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs4319547 0.774 rs7295105 chr12:123124225 G/A cg05707623 chr12:122985044 ZCCHC8 -0.65 -5.52 -0.44 1.89e-7 Body mass index; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg24846343 chr22:24311635 DDTL -0.23 -5.85 -0.46 4.17e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10804591 1.000 rs2811437 chr3:129339045 A/C cg07730360 chr3:128845626 NA 0.2 4.62 0.38 9.34e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs208520 0.690 rs3843513 chr6:66836797 A/G cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs2456568 0.805 rs55649862 chr11:93682888 G/T cg16099599 chr11:93583650 C11orf90 -0.39 -4.69 -0.39 7.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7085104 0.514 rs284855 chr10:104574422 A/G cg05855489 chr10:104503620 C10orf26 -0.63 -6.21 -0.49 7.3e-9 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs8014204 0.604 rs7156590 chr14:75388183 C/T cg06637938 chr14:75390232 RPS6KL1 0.89 9.2 0.64 1.09e-15 Caffeine consumption; TGCT cis rs1372520 0.935 rs1372519 chr4:90757309 A/G cg20003494 chr4:90757398 SNCA -0.65 -5.17 -0.42 9.26e-7 Neuroticism; TGCT cis rs7017914 0.967 rs6472538 chr8:71586971 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs2046867 0.818 rs7620212 chr3:72778610 C/T cg25664220 chr3:72788482 NA -0.56 -7.03 -0.53 1.25e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.579 rs7672718 chr4:98645122 A/G cg17366294 chr4:99064904 C4orf37 0.58 5.4 0.44 3.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11105298 0.891 rs6538190 chr12:89885942 T/C cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6988636 1.000 rs17323510 chr8:124186089 A/G cg23067535 chr8:124195133 FAM83A 0.35 5.37 0.43 3.79e-7 Urinary uromodulin levels; TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg22166914 chr1:53195759 ZYG11B 0.3 4.85 0.4 3.62e-6 Monocyte count; TGCT cis rs2050392 0.894 rs303430 chr10:30706235 C/A cg18806716 chr10:30721971 MAP3K8 -0.47 -5.53 -0.44 1.82e-7 Inflammatory bowel disease; TGCT cis rs73815153 0.744 rs77736838 chr5:180463764 A/G cg00299286 chr5:180478185 BTNL9 0.86 4.95 0.41 2.36e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs1008375 1.000 rs1974624 chr4:17650281 A/G cg18681998 chr4:17616180 MED28 1.02 12.01 0.73 1.65e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1538970 0.781 rs11211139 chr1:46015751 G/T cg05343316 chr1:45956843 TESK2 0.7 5.34 0.43 4.26e-7 Platelet count; TGCT cis rs875971 0.756 rs4718328 chr7:65693337 A/G cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.27e-7 Aortic root size; TGCT cis rs3015497 0.616 rs34061700 chr14:51084860 G/A cg04730355 chr14:51134070 SAV1 -0.64 -6.33 -0.49 4.12e-9 Mean platelet volume; TGCT cis rs832540 0.898 rs252888 chr5:56227326 T/A cg12311346 chr5:56204834 C5orf35 -0.41 -4.45 -0.37 1.87e-5 Coronary artery disease; TGCT cis rs858239 0.600 rs4321896 chr7:23128056 G/A cg05602783 chr7:23145260 KLHL7 -0.58 -4.85 -0.4 3.68e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9811920 0.683 rs1718235 chr3:99583484 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.42 4.9 0.4 2.98e-6 Axial length; TGCT cis rs12681287 0.752 rs12548328 chr8:87311219 G/A cg27223183 chr8:87520930 FAM82B -0.85 -6.4 -0.5 2.9e-9 Caudate activity during reward; TGCT cis rs7216064 1.000 rs3935969 chr17:65881959 A/G cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs11098499 0.754 rs10518300 chr4:120249499 G/T cg09307838 chr4:120376055 NA -0.62 -5.58 -0.45 1.43e-7 Corneal astigmatism; TGCT cis rs9640161 0.830 rs3735165 chr7:150068371 T/C cg10018233 chr7:150070692 REPIN1 0.42 6.94 0.53 1.97e-10 Blood protein levels;Circulating chemerin levels; TGCT cis rs9611565 0.512 rs6519289 chr22:42170432 A/C cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs7081476 0.826 rs73596338 chr10:27259964 G/C cg15469871 chr10:27541418 LOC387646 -0.97 -4.57 -0.38 1.14e-5 Age-related diseases and mortality;Age-related diseases, mortality and associated endophenotypes; TGCT trans rs9951602 0.541 rs56882694 chr18:76647010 C/T cg02800362 chr5:177631904 HNRNPAB 1.13 12.98 0.76 7.25e-25 Obesity-related traits; TGCT cis rs67478160 0.644 rs7159810 chr14:104294117 T/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs3008870 1.000 rs7511948 chr1:67430427 A/G cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs6657613 0.903 rs2076605 chr1:17313157 G/A cg21692666 chr1:17199302 NA -0.42 -4.52 -0.38 1.43e-5 Hip circumference adjusted for BMI; TGCT cis rs73001065 0.792 rs17216525 chr19:19662220 C/T cg03709012 chr19:19516395 GATAD2A 1.0 4.66 0.39 8.05e-6 LDL cholesterol; TGCT cis rs694739 0.541 rs61886926 chr11:64133552 C/T cg23796481 chr11:64053134 BAD;GPR137 0.63 6.54 0.51 1.44e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs1362153 1.000 rs1362153 chr1:44469031 T/C cg12908607 chr1:44402522 ARTN 0.71 4.73 0.39 5.96e-6 Alcohol dependence (age at onset); TGCT cis rs360798 0.512 rs4671050 chr2:62988169 G/T cg17519650 chr2:63277830 OTX1 -0.6 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs2721195 0.845 rs756627 chr8:145737286 G/A cg11211951 chr8:145729740 GPT 0.27 6.34 0.49 3.93e-9 Age at first birth; TGCT cis rs1799949 0.930 rs3092987 chr17:41222723 T/C cg23758822 chr17:41437982 NA 0.71 6.83 0.52 3.46e-10 Menopause (age at onset); TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg25703541 chr22:24373054 LOC391322 0.96 12.14 0.74 7.85e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2404602 0.716 rs284895 chr15:76751225 C/G cg26408565 chr15:76604113 ETFA 0.39 5.13 0.42 1.08e-6 Blood metabolite levels; TGCT cis rs7666738 0.830 rs7664305 chr4:99037691 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.64 0.57 5.19e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7552404 0.731 rs5745491 chr1:76350159 T/G cg10523679 chr1:76189770 ACADM -0.82 -7.56 -0.56 7.75e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6882076 0.961 rs55776147 chr5:156400808 A/G cg12943317 chr5:156479607 HAVCR1 -0.31 -5.82 -0.46 4.71e-8 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs10832963 1.000 rs10128711 chr11:18632984 A/G cg20219074 chr11:18656078 SPTY2D1 0.97 9.5 0.65 2.02e-16 Breast cancer; TGCT cis rs11809207 0.903 rs17257148 chr1:26526348 G/C cg03844060 chr1:26490628 NA 0.26 4.67 0.39 7.63e-6 Height; TGCT cis rs1008375 0.966 rs2302393 chr4:17654341 G/A cg16339924 chr4:17578868 LAP3 0.63 5.39 0.44 3.48e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs597539 0.652 rs674654 chr11:68698762 G/T cg06112835 chr11:68658793 MRPL21 0.45 7.64 0.57 5.19e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6693567 0.565 rs6684939 chr1:150440563 G/A cg09579323 chr1:150459698 TARS2 -0.52 -4.62 -0.38 9.55e-6 Migraine; TGCT cis rs55823223 0.646 rs74410877 chr17:73832384 C/T cg23806715 chr17:73775811 H3F3B 0.85 5.77 0.46 5.93e-8 Psoriasis; TGCT cis rs12210905 0.688 rs72843151 chr6:27359268 A/C cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs4766566 0.651 rs933306 chr12:111737985 A/T cg10833066 chr12:111807467 FAM109A 0.4 7.56 0.56 7.74e-12 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs2970818 0.831 rs2970808 chr12:4640362 C/T cg02722637 chr12:4922070 KCNA6 0.34 4.73 0.39 6.1e-6 Phosphorus levels; TGCT cis rs36051895 0.659 rs10283730 chr9:5073289 G/A cg02405213 chr9:5042618 JAK2 -0.79 -10.23 -0.68 3.48e-18 Pediatric autoimmune diseases; TGCT cis rs7267979 1.000 rs2482937 chr20:25340786 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1053338 0.529 rs17069316 chr3:63713969 C/T cg22134162 chr3:63841271 THOC7 0.31 4.72 0.39 6.36e-6 Breast cancer; TGCT cis rs6938 0.514 rs35556055 chr15:75253414 G/A cg09165964 chr15:75287851 SCAMP5 0.52 4.7 0.39 6.92e-6 Breast cancer; TGCT cis rs9381040 0.655 rs2268188 chr6:41042590 T/G cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs709400 0.663 rs10141388 chr14:103939679 A/G cg26031613 chr14:104095156 KLC1 0.85 9.75 0.66 5.13e-17 Body mass index; TGCT cis rs11644362 1.000 rs4505301 chr16:12989467 A/G cg06890432 chr16:12997467 SHISA9 -0.61 -6.7 -0.52 6.46e-10 Positive affect;Subjective well-being; TGCT cis rs7546094 0.509 rs7415988 chr1:113159730 G/T cg22162597 chr1:113214053 CAPZA1 -0.28 -5.83 -0.46 4.4e-8 Platelet distribution width; TGCT cis rs35306767 0.761 rs12771539 chr10:1050653 A/G cg20503657 chr10:835505 NA 0.61 6.71 0.52 6.11e-10 Eosinophil percentage of granulocytes; TGCT cis rs12681287 0.640 rs6471314 chr8:87400459 G/A cg27223183 chr8:87520930 FAM82B 0.87 6.39 0.5 3e-9 Caudate activity during reward; TGCT cis rs35883536 1.000 rs6663612 chr1:101085835 A/G cg06223162 chr1:101003688 GPR88 0.31 4.93 0.4 2.63e-6 Monocyte count; TGCT cis rs1372520 0.684 rs2197120 chr4:90729602 A/G cg26578617 chr4:90757533 SNCA -0.52 -4.44 -0.37 1.99e-5 Neuroticism; TGCT cis rs877282 0.898 rs11253353 chr10:766862 C/A cg17470449 chr10:769945 NA 0.36 5.36 0.43 3.85e-7 Uric acid levels; TGCT cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs12478296 1.000 rs59036157 chr2:243040228 C/A cg06360820 chr2:242988706 NA -0.81 -5.39 -0.44 3.36e-7 Obesity-related traits; TGCT cis rs7714584 1.000 rs3906528 chr5:150266718 G/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs6490294 0.659 rs608848 chr12:112146964 C/T cg10833066 chr12:111807467 FAM109A 0.3 4.71 0.39 6.54e-6 Mean platelet volume; TGCT cis rs6570726 0.791 rs6902410 chr6:145905261 G/A cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg20607798 chr8:58055168 NA 0.49 4.52 0.38 1.43e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.753 rs34164013 chr4:98976333 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7681440 0.904 rs28403500 chr4:90769729 T/G cg26578617 chr4:90757533 SNCA -0.46 -4.83 -0.4 3.96e-6 Dementia with Lewy bodies; TGCT cis rs2933343 1.000 rs876755 chr3:128627933 C/T cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs28595532 0.920 rs56027489 chr4:119780882 A/G cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs10504229 1.000 rs17217033 chr8:58180061 G/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9902453 1.000 rs9902453 chr17:28349095 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.61 -0.51 1.03e-9 Coffee consumption (cups per day); TGCT cis rs7095607 0.777 rs2101483 chr10:69922987 G/A cg18986048 chr10:69913749 MYPN 0.48 5.57 0.45 1.54e-7 Lung function (FVC); TGCT cis rs10782582 0.593 rs114421765 chr1:76141802 C/T cg03433033 chr1:76189801 ACADM -0.64 -7.25 -0.55 3.84e-11 Daytime sleep phenotypes; TGCT cis rs9581857 1.000 rs9581857 chr13:28027714 A/C cg22138327 chr13:27999177 GTF3A 0.76 5.41 0.44 3.1e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2688608 0.967 rs9971038 chr10:75661149 C/T cg23231163 chr10:75533350 FUT11 -0.27 -4.74 -0.39 5.8e-6 Inflammatory bowel disease; TGCT cis rs4851266 1.000 rs11695383 chr2:100826098 G/T cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs9733 0.596 rs1415148 chr1:150705755 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs3749237 1.000 rs11717256 chr3:49868520 C/T cg03060546 chr3:49711283 APEH 0.69 7.12 0.54 7.8e-11 Resting heart rate; TGCT cis rs433598 0.514 rs56073015 chr16:20679391 A/G cg08248577 chr16:19727447 IQCK;C16orf88 -0.25 -4.82 -0.4 4.13e-6 Schizophrenia; TGCT cis rs17433780 0.666 rs2624 chr1:89518623 C/T cg09516651 chr1:89888402 LOC400759 -0.25 -4.86 -0.4 3.42e-6 Carotid intima media thickness; TGCT cis rs4512344 0.510 rs35181953 chr8:11435049 G/A cg21775007 chr8:11205619 TDH -0.53 -5.01 -0.41 1.85e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs3806843 1.000 rs13157397 chr5:140184442 G/A cg19875535 chr5:140030758 IK 0.37 6.15 0.48 9.73e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg06640241 chr16:89574553 SPG7 0.74 8.16 0.59 3.13e-13 Multiple myeloma (IgH translocation); TGCT cis rs11711311 1.000 rs9809850 chr3:113429010 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -6.76 -0.52 4.88e-10 IgG glycosylation; TGCT cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg07424592 chr7:64974309 NA 1.27 7.86 0.58 1.61e-12 Diabetic kidney disease; TGCT cis rs2439831 1.000 rs2444250 chr15:43785051 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.19 0.59 2.67e-13 Lung cancer in ever smokers; TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg17345569 chr6:42928274 GNMT -0.47 -4.92 -0.4 2.75e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1552244 0.882 rs36006511 chr3:10054191 C/T cg00149659 chr3:10157352 C3orf10 0.78 4.99 0.41 2.04e-6 Alzheimer's disease; TGCT cis rs4443656 0.711 rs7826330 chr8:21548665 G/A cg26401870 chr8:21882439 NPM2 -0.47 -4.61 -0.38 9.76e-6 Blood protein levels; TGCT cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg04744514 chr10:134541379 INPP5A 0.25 4.47 0.37 1.73e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2228479 0.850 rs12598276 chr16:89829196 G/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs116095464 0.558 rs28635197 chr5:279071 T/C cg22857025 chr5:266934 NA -0.34 -6.83 -0.52 3.42e-10 Breast cancer; TGCT cis rs1784581 0.588 rs6455789 chr6:162417948 C/T cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.07e-9 Itch intensity from mosquito bite; TGCT cis rs9677476 0.516 rs6706191 chr2:232040047 T/G cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs8180040 1.000 rs1076394 chr3:47322781 G/A cg27129171 chr3:47204927 SETD2 -0.7 -8.64 -0.61 2.35e-14 Colorectal cancer; TGCT cis rs9311474 0.508 rs4687629 chr3:52615227 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs6840360 0.593 rs1877185 chr4:152690348 C/T cg22705602 chr4:152727874 NA -0.35 -5.78 -0.46 5.68e-8 Intelligence (multi-trait analysis); TGCT cis rs16867321 0.618 rs17455242 chr2:181476558 G/A cg23363182 chr2:181467187 NA -0.42 -4.54 -0.38 1.3e-5 Obesity; TGCT cis rs3820928 0.874 rs4675130 chr2:227827740 G/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.61 -0.38 9.73e-6 Pulmonary function; TGCT cis rs7267979 1.000 rs447722 chr20:25443510 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3796352 1.000 rs34340609 chr3:53077276 A/G cg27565382 chr3:53032988 SFMBT1 0.41 4.47 0.37 1.73e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11249608 0.548 rs10516150 chr5:178459169 G/C cg21905437 chr5:178450457 ZNF879 0.45 4.65 0.39 8.3e-6 Pubertal anthropometrics; TGCT cis rs4727027 0.866 rs7778766 chr7:148806729 A/G cg23583168 chr7:148888333 NA -0.72 -9.16 -0.64 1.34e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6840360 0.615 rs12647616 chr4:152607662 G/A cg22705602 chr4:152727874 NA -0.32 -5.43 -0.44 2.85e-7 Intelligence (multi-trait analysis); TGCT cis rs556990 0.570 rs5960 chr13:113801737 C/T cg00898013 chr13:113819073 PROZ 0.56 6.99 0.53 1.48e-10 Blood protein levels; TGCT cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg18305652 chr10:134549665 INPP5A -0.33 -5.27 -0.43 5.96e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17376456 0.825 rs28412976 chr5:93248377 T/C cg21475434 chr5:93447410 FAM172A 0.7 4.62 0.38 9.34e-6 Diabetic retinopathy; TGCT cis rs8031584 0.678 rs35098644 chr15:31145440 A/G cg14829155 chr15:31115871 NA -0.35 -4.51 -0.38 1.46e-5 Huntington's disease progression; TGCT cis rs4862307 0.836 rs13107384 chr4:185004073 C/T cg06737308 chr4:185021514 ENPP6 -0.35 -5.03 -0.41 1.7e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs7714584 0.826 rs12655654 chr5:150174295 A/C cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs56104184 0.775 rs55981795 chr19:49401952 A/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2486288 0.539 rs2433601 chr15:45716425 T/C cg26924012 chr15:45694286 SPATA5L1 0.8 9.1 0.63 1.83e-15 Glomerular filtration rate; TGCT cis rs904251 1.000 rs904251 chr6:37451696 G/T cg25019722 chr6:37503610 NA -0.47 -6.26 -0.49 5.69e-9 Cognitive performance; TGCT cis rs1008375 0.966 rs2191504 chr4:17675592 C/G cg16339924 chr4:17578868 LAP3 0.55 4.76 0.39 5.3e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6424115 0.931 rs2982390 chr1:24147830 G/C cg15997130 chr1:24165203 NA 0.92 10.57 0.69 5.26e-19 Immature fraction of reticulocytes; TGCT cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg03452623 chr4:187889614 NA 0.33 5.04 0.41 1.59e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11690935 0.632 rs12987931 chr2:172900948 C/T cg13550731 chr2:172543902 DYNC1I2 0.74 6.73 0.52 5.53e-10 Schizophrenia; TGCT cis rs7681440 0.904 rs28403500 chr4:90769729 T/G cg14346243 chr4:90757452 SNCA -0.55 -5.4 -0.44 3.34e-7 Dementia with Lewy bodies; TGCT cis rs2479724 0.901 rs2185798 chr6:41773576 G/C cg08135965 chr6:41755394 TOMM6 -0.49 -4.77 -0.39 5.1e-6 Menarche (age at onset); TGCT cis rs10875746 0.551 rs10875799 chr12:48740879 C/A cg20731937 chr12:48336164 NA 0.57 4.47 0.37 1.75e-5 Longevity (90 years and older); TGCT cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg18230493 chr5:56204884 C5orf35 -0.67 -5.88 -0.47 3.5e-8 Initial pursuit acceleration; TGCT cis rs2013441 1.000 rs2526467 chr17:20165054 T/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs6840360 0.642 rs7682837 chr4:152427686 C/T cg17479576 chr4:152424074 FAM160A1 -0.57 -6.02 -0.48 1.85e-8 Intelligence (multi-trait analysis); TGCT cis rs17030434 0.784 rs67664355 chr4:154660229 A/G cg14289246 chr4:154710475 SFRP2 -0.88 -7.57 -0.56 7.4e-12 Electrocardiographic conduction measures; TGCT cis rs3008870 0.755 rs2755251 chr1:67496425 G/T cg11518657 chr1:67396239 MIER1 0.48 4.74 0.39 5.69e-6 Lymphocyte percentage of white cells; TGCT cis rs9297145 0.916 rs6969140 chr7:98753900 G/A cg05967295 chr7:98741636 SMURF1 -1.04 -16.25 -0.82 1.66e-32 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs7824557 0.806 rs10503418 chr8:11118983 C/T cg21775007 chr8:11205619 TDH -0.56 -5.66 -0.45 1e-7 Retinal vascular caliber; TGCT cis rs6582630 0.621 rs10880656 chr12:38571220 A/C cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs75059851 1.000 rs73036064 chr11:133829442 G/A cg14047540 chr11:133829660 NA -0.53 -5.25 -0.43 6.44e-7 Schizophrenia; TGCT cis rs7255045 0.788 rs7250751 chr19:12962648 A/G cg23899408 chr19:12877188 HOOK2 -0.61 -4.99 -0.41 1.97e-6 Mean corpuscular volume; TGCT cis rs7727544 1.000 rs10076701 chr5:131596419 A/G cg00255919 chr5:131827918 IRF1 -0.21 -4.71 -0.39 6.65e-6 Blood metabolite levels; TGCT cis rs986417 0.748 rs2179971 chr14:61055466 T/C cg27398547 chr14:60952738 C14orf39 1.33 9.93 0.67 1.82e-17 Gut microbiota (bacterial taxa); TGCT cis rs13424612 1.000 rs1465880 chr2:240932326 G/A cg26363272 chr2:240904871 NDUFA10 0.28 4.66 0.39 7.96e-6 Odorant perception (isobutyraldehyde); TGCT cis rs9549367 0.789 rs9549701 chr13:113881752 G/C cg18105134 chr13:113819100 PROZ -0.34 -5.45 -0.44 2.63e-7 Platelet distribution width; TGCT cis rs7681440 0.874 rs10028246 chr4:90766704 G/A cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs735396 0.595 rs2258287 chr12:121454313 G/T cg15155738 chr12:121454335 C12orf43 0.57 5.25 0.43 6.33e-7 N-glycan levels; TGCT cis rs9913156 0.748 rs72835619 chr17:4557285 G/A cg00122941 chr17:4613640 ARRB2 0.87 7.38 0.55 1.95e-11 Lymphocyte counts; TGCT cis rs3008870 0.958 rs12143044 chr1:67460054 A/T cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs9796 0.689 rs72737758 chr15:41449778 C/T cg18705301 chr15:41695430 NDUFAF1 -0.51 -6.42 -0.5 2.56e-9 Menopause (age at onset); TGCT cis rs3796352 0.892 rs3821872 chr3:53080555 C/G cg07884673 chr3:53033167 SFMBT1 -0.56 -6.17 -0.48 8.87e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs5769765 0.954 rs6009900 chr22:50236610 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.56 0.45 1.59e-7 Schizophrenia; TGCT cis rs2243480 0.901 rs778732 chr7:65822360 C/T cg20637647 chr7:64974828 NA 0.9 5.0 0.41 1.93e-6 Diabetic kidney disease; TGCT cis rs7909074 1.000 rs4948925 chr10:45392455 C/T cg04218760 chr10:45406644 TMEM72 -0.28 -5.63 -0.45 1.14e-7 Mean corpuscular volume; TGCT cis rs7208859 0.623 rs7223209 chr17:29107220 C/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs709400 0.832 rs55864158 chr14:104068579 G/A cg26031613 chr14:104095156 KLC1 1.15 16.05 0.82 4.72e-32 Body mass index; TGCT cis rs9486719 0.895 rs12195315 chr6:96905711 T/G cg18709589 chr6:96969512 KIAA0776 -0.68 -5.05 -0.41 1.55e-6 Migraine;Coronary artery disease; TGCT cis rs1045714 0.895 rs4721860 chr7:2639994 C/T cg17215154 chr7:2644645 IQCE 0.28 4.97 0.41 2.2e-6 Urate levels in lean individuals; TGCT cis rs7258465 1.000 rs34256197 chr19:18606472 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs910316 0.737 rs108622 chr14:75481908 A/G cg08847533 chr14:75593920 NEK9 -0.84 -8.92 -0.63 5.19e-15 Height; TGCT cis rs3784262 0.528 rs10518961 chr15:58334345 G/A cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.39 -0.5 3.11e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg18305652 chr10:134549665 INPP5A 0.35 5.94 0.47 2.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2742234 0.910 rs2505513 chr10:43633537 C/G cg02780029 chr10:43622663 RET -0.26 -5.03 -0.41 1.67e-6 Hirschsprung disease; TGCT cis rs1215050 0.716 rs356549 chr4:98699344 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2688608 0.592 rs11814282 chr10:75490217 T/C cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg02953382 chr22:24373134 LOC391322 -0.75 -7.83 -0.58 1.82e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs425277 0.520 rs10910030 chr1:2035684 C/T cg24578937 chr1:2090814 PRKCZ -0.24 -5.34 -0.43 4.22e-7 Height; TGCT cis rs910316 1.000 rs10143132 chr14:75525850 G/A cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs9325144 0.560 rs11182930 chr12:38633693 A/T cg26384229 chr12:38710491 ALG10B -0.66 -5.98 -0.47 2.23e-8 Morning vs. evening chronotype; TGCT cis rs7255045 0.752 rs10404876 chr19:12987605 T/C cg06537894 chr19:12978706 MAST1 -0.49 -4.47 -0.37 1.73e-5 Mean corpuscular volume; TGCT cis rs838147 0.563 rs2638282 chr19:49213833 G/A cg05248581 chr19:49925731 PTH2 0.42 4.44 0.37 1.94e-5 Dietary macronutrient intake; TGCT cis rs6461049 0.800 rs2398706 chr7:2156338 A/T cg22963979 chr7:1858916 MAD1L1 -0.42 -6.67 -0.51 7.72e-10 Schizophrenia; TGCT cis rs208520 0.909 rs58958359 chr6:67021381 A/C cg07460842 chr6:66804631 NA 0.69 5.72 0.46 7.53e-8 Exhaled nitric oxide output; TGCT cis rs208520 0.690 rs2797693 chr6:66868985 T/C cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg08280861 chr8:58055591 NA 0.51 5.56 0.45 1.58e-7 Developmental language disorder (linguistic errors); TGCT cis rs67311347 0.911 rs6773917 chr3:40469254 G/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs12477438 0.798 rs1993230 chr2:99686079 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs9394841 0.778 rs9349204 chr6:41914378 A/G cg08135965 chr6:41755394 TOMM6 0.54 5.1 0.42 1.24e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs6088590 0.523 rs6059913 chr20:33143288 G/A cg08999081 chr20:33150536 PIGU 0.28 5.41 0.44 3.11e-7 Coronary artery disease; TGCT cis rs60843830 1.000 rs56321614 chr2:268191 G/T cg00108164 chr2:264199 ACP1;SH3YL1 0.71 6.78 0.52 4.33e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs881375 0.967 rs2270231 chr9:123650982 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.5 5.5 0.44 2.03e-7 Rheumatoid arthritis; TGCT cis rs8017423 0.967 rs11628881 chr14:90713833 C/T cg04374321 chr14:90722782 PSMC1 0.75 7.76 0.57 2.67e-12 Mortality in heart failure; TGCT cis rs8014204 0.657 rs2884668 chr14:75281576 T/A cg06637938 chr14:75390232 RPS6KL1 0.55 4.91 0.4 2.81e-6 Caffeine consumption; TGCT cis rs9393777 0.513 rs9393737 chr6:26617306 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 0.55 5.08 0.42 1.35e-6 Intelligence (multi-trait analysis); TGCT cis rs9914544 0.545 rs9912713 chr17:18771145 G/A cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs1552244 0.572 rs6442154 chr3:10168785 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs4629710 0.592 rs11758994 chr6:131582022 A/C cg12606694 chr6:131520996 AKAP7 0.38 4.53 0.38 1.35e-5 Multiple myeloma (IgH translocation); TGCT cis rs17076896 0.786 rs58325432 chr13:19938351 A/G cg00777926 chr13:20807375 GJB6 -0.41 -4.82 -0.4 4.03e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs17384381 0.953 rs12138621 chr1:85783970 T/C cg16011679 chr1:85725395 C1orf52 0.87 6.73 0.52 5.65e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg03264133 chr6:25882463 NA 0.49 4.55 0.38 1.24e-5 Intelligence (multi-trait analysis); TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg16031515 chr1:205743344 RAB7L1 -0.27 -4.56 -0.38 1.2e-5 Menarche (age at onset); TGCT cis rs3008870 0.585 rs2815382 chr1:67515228 G/A cg02640540 chr1:67518911 SLC35D1 0.64 6.06 0.48 1.51e-8 Lymphocyte percentage of white cells; TGCT cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs7044106 0.762 rs1547267 chr9:123408736 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.62 6.6 0.51 1.08e-9 Hip circumference adjusted for BMI; TGCT cis rs1577917 0.917 rs2197651 chr6:86495442 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.46 -0.44 2.47e-7 Response to antipsychotic treatment; TGCT cis rs9788721 1.000 rs8031948 chr15:78816057 G/T cg18825076 chr15:78729989 IREB2 -0.31 -4.65 -0.39 8.24e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs981844 1.000 rs62325083 chr4:154661775 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs12900413 0.603 rs12909833 chr15:90301518 G/A cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7267979 0.934 rs2261115 chr20:25259807 G/A cg14121845 chr20:25566513 NINL 0.51 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs739496 0.579 rs7976557 chr12:112300780 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.4 0.55 1.78e-11 Schizophrenia; TGCT cis rs1043515 0.748 rs11657530 chr17:36942814 T/C cg09592244 chr17:37024020 NA 0.49 4.69 0.39 7.22e-6 Height; TGCT cis rs9549367 0.713 rs3024746 chr13:113821777 G/A cg00898013 chr13:113819073 PROZ -0.53 -6.74 -0.52 5.25e-10 Platelet distribution width; TGCT cis rs2439831 0.717 rs690170 chr15:43810422 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.94 5.77 0.46 5.9e-8 Lung cancer in ever smokers; TGCT cis rs7674212 0.531 rs10006474 chr4:103928047 A/G cg16532752 chr4:104119610 CENPE -0.54 -4.64 -0.38 8.77e-6 Type 2 diabetes; TGCT cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg08219700 chr8:58056026 NA 0.38 5.0 0.41 1.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.962 rs1060490 chr20:61665871 A/G cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT trans rs10435719 0.867 rs34465618 chr8:11791356 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs7943203 0.524 rs373759 chr11:108220657 C/T cg04873221 chr11:107992290 ACAT1 -0.6 -5.24 -0.43 6.68e-7 Red blood cell count;Mean corpuscular volume; TGCT cis rs9303401 0.659 rs34878689 chr17:56694330 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs17253792 0.822 rs77182097 chr14:56136695 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs7507204 1.000 rs7507204 chr19:3428834 G/C cg08380311 chr19:3435252 NFIC 0.94 8.14 0.59 3.48e-13 Height; TGCT cis rs2239547 0.563 rs2581820 chr3:53020544 A/G cg11645453 chr3:52864694 ITIH4 -0.34 -5.63 -0.45 1.12e-7 Schizophrenia; TGCT cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT trans rs12191082 0.646 rs35965624 chr6:46880137 G/T cg15621338 chr7:128577916 IRF5 -1.26 -6.89 -0.53 2.44e-10 Mean platelet volume; TGCT cis rs4072705 0.967 rs10818979 chr9:127336913 G/A cg13476313 chr9:127244764 NR5A1 0.28 4.5 0.38 1.51e-5 Menarche (age at onset); TGCT cis rs11098499 0.863 rs11736416 chr4:120431661 C/T cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.28e-9 Corneal astigmatism; TGCT cis rs6599388 0.803 rs11248057 chr4:906131 C/G cg17500754 chr4:1581635 NA 0.38 5.07 0.41 1.42e-6 Parkinson's disease; TGCT cis rs36051895 0.564 rs7874624 chr9:5179865 A/G cg02405213 chr9:5042618 JAK2 -0.76 -10.76 -0.69 1.8e-19 Pediatric autoimmune diseases; TGCT cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs568617 1.000 rs687672 chr11:65649984 T/C cg04055107 chr11:65626734 MUS81;CFL1 -0.54 -4.69 -0.39 7.03e-6 Crohn's disease; TGCT cis rs1348850 0.872 rs4893824 chr2:178298104 G/A cg22681709 chr2:178499509 PDE11A -0.38 -4.73 -0.39 6.12e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs367943 1.000 rs168366 chr5:112818587 C/T cg12552261 chr5:112820674 MCC 0.24 4.91 0.4 2.81e-6 Type 2 diabetes; TGCT cis rs7811142 0.830 rs6979910 chr7:99940630 A/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.84 0.4 3.86e-6 Platelet count; TGCT cis rs6430585 0.528 rs309158 chr2:136680534 A/G cg07169764 chr2:136633963 MCM6 1.2 11.66 0.72 1.12e-21 Corneal structure; TGCT cis rs11098499 0.908 rs7696649 chr4:120322177 G/A cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.25e-9 Corneal astigmatism; TGCT cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg24675658 chr1:53192096 ZYG11B 0.87 11.26 0.71 1.08e-20 Monocyte count; TGCT cis rs9926296 0.535 rs36022917 chr16:89893238 A/G cg27121462 chr16:89883253 FANCA 0.53 4.94 0.41 2.48e-6 Vitiligo; TGCT cis rs587847 0.737 rs4923744 chr15:37665412 T/C cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs13242816 1.000 rs34678019 chr7:116189490 A/G cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg18765753 chr7:1198926 ZFAND2A -0.41 -4.53 -0.38 1.39e-5 Longevity;Endometriosis; TGCT cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs709400 0.663 rs62007719 chr14:103943130 G/T cg26031613 chr14:104095156 KLC1 0.86 9.73 0.66 5.62e-17 Body mass index; TGCT cis rs1448094 0.773 rs11117100 chr12:86310392 A/G cg00310523 chr12:86230176 RASSF9 0.33 4.54 0.38 1.32e-5 Major depressive disorder; TGCT trans rs7819412 0.806 rs2898256 chr8:10932695 G/C cg15556689 chr8:8085844 FLJ10661 -0.81 -7.77 -0.57 2.51e-12 Triglycerides; TGCT cis rs2692947 0.702 rs2312955 chr2:96777168 T/G cg05933789 chr2:97190408 NA -0.16 -4.74 -0.39 5.75e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg02487422 chr3:49467188 NICN1 0.52 4.91 0.4 2.84e-6 Menarche (age at onset); TGCT cis rs9926296 0.533 rs12102290 chr16:89812617 C/T cg26513180 chr16:89883248 FANCA 1.07 14.67 0.8 7.16e-29 Vitiligo; TGCT cis rs4727027 0.870 rs62507509 chr7:148795522 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.68 0.39 7.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6500602 0.673 rs1861652 chr16:4505331 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.35 6.09 0.48 1.32e-8 Schizophrenia; TGCT cis rs2404602 1.000 rs12898430 chr15:76874923 G/A cg22467129 chr15:76604101 ETFA -0.44 -4.86 -0.4 3.41e-6 Blood metabolite levels; TGCT cis rs2842992 0.789 rs2842969 chr6:160145364 C/T cg11366901 chr6:160182831 ACAT2 1.02 6.82 0.52 3.57e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs6076065 0.609 rs3746736 chr20:23424613 T/C cg11657817 chr20:23433608 CST11 0.34 6.34 0.49 3.87e-9 Facial morphology (factor 15, philtrum width); TGCT cis rs7666738 0.830 rs17558193 chr4:99049593 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs17094222 0.504 rs4917904 chr10:102447292 G/A cg26540559 chr10:102447443 NA 0.35 4.73 0.39 5.89e-6 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2153535 0.580 rs9392224 chr6:8472614 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7666738 0.546 rs28444809 chr4:98916934 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.5 0.37 1.55e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.83e-5 Obesity-related traits; TGCT trans rs208520 0.608 rs3846803 chr6:66805743 C/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.57 -5.42 -0.44 2.99e-7 Menarche (age at onset); TGCT cis rs28595532 0.920 rs56212415 chr4:119737731 C/T cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs9611519 0.558 rs8137906 chr22:41442566 A/G cg03806693 chr22:41940476 POLR3H -0.59 -5.42 -0.44 2.97e-7 Neuroticism; TGCT cis rs3096299 0.719 rs2965817 chr16:89513234 C/T cg08392591 chr16:89556376 ANKRD11 0.6 5.76 0.46 6.28e-8 Multiple myeloma (IgH translocation); TGCT trans rs4919669 0.546 rs2902544 chr10:104261359 C/T cg19053889 chr7:1098703 C7orf50;GPR146 0.51 6.77 0.52 4.63e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs916888 0.773 rs199447 chr17:44812188 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.64 -5.6 -0.45 1.32e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9796 0.621 rs2918462 chr15:41481254 A/G cg18705301 chr15:41695430 NDUFAF1 0.52 7.18 0.54 5.68e-11 Menopause (age at onset); TGCT cis rs12681287 0.517 rs13249753 chr8:87513216 A/G cg19078186 chr8:87526527 CPNE3 -0.38 -4.73 -0.39 6.04e-6 Caudate activity during reward; TGCT cis rs9393777 0.513 rs34388707 chr6:27050396 A/G cg16898833 chr6:26189333 HIST1H4D 0.8 4.85 0.4 3.57e-6 Intelligence (multi-trait analysis); TGCT cis rs10779751 0.960 rs1883964 chr1:11294942 T/A cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs6540559 0.546 rs57315825 chr1:210030197 C/T cg04352962 chr1:209979756 IRF6 0.74 5.21 0.42 7.7e-7 Cleft lip with or without cleft palate; TGCT cis rs28386778 0.799 rs2665802 chr17:61995030 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.95 -12.8 -0.75 2e-24 Prudent dietary pattern; TGCT cis rs763014 0.931 rs7191939 chr16:630089 C/T cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs3796352 1.000 rs35163227 chr3:53127876 A/G cg15956490 chr3:53032818 SFMBT1 0.5 5.38 0.43 3.65e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10504229 0.593 rs12216730 chr8:58003894 C/T cg08280861 chr8:58055591 NA 0.34 4.79 0.39 4.75e-6 Developmental language disorder (linguistic errors); TGCT cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg26531700 chr6:26746687 NA 0.52 4.71 0.39 6.66e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2188554 0.785 rs7789741 chr7:117206941 T/G cg09181792 chr7:117119393 CFTR 0.52 4.68 0.39 7.3e-6 Esophageal adenocarcinoma; TGCT cis rs7246657 1.000 rs35398388 chr19:37740358 A/G cg18154014 chr19:37997991 ZNF793 0.84 5.58 0.45 1.46e-7 Coronary artery calcification; TGCT cis rs4919694 0.808 rs80020194 chr10:105035954 A/G cg04362960 chr10:104952993 NT5C2 1.02 6.5 0.5 1.73e-9 Arsenic metabolism; TGCT cis rs1697139 0.583 rs17289614 chr5:66541592 G/A cg11553311 chr5:66541588 NA 0.27 5.82 0.46 4.78e-8 Breast cancer; TGCT cis rs2070433 0.660 rs11701034 chr21:47793235 A/G cg12379764 chr21:47803548 PCNT 0.61 4.9 0.4 2.95e-6 Lymphocyte counts; TGCT cis rs2469997 0.858 rs2470007 chr8:120358833 T/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs4689388 0.926 rs4308429 chr4:6294001 A/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10791097 0.678 rs10894272 chr11:130731081 A/G cg05962950 chr11:130786565 SNX19 0.84 10.27 0.68 2.87e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs10751667 0.666 rs10902255 chr11:967268 T/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.66e-13 Alzheimer's disease (late onset); TGCT cis rs12497850 0.897 rs6795025 chr3:49081247 T/C cg05785598 chr3:49045655 WDR6 0.36 4.8 0.4 4.48e-6 Parkinson's disease; TGCT cis rs12451471 0.637 rs7567 chr17:78093549 G/T cg06718696 chr17:78121285 EIF4A3 0.75 6.24 0.49 6.38e-9 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs17270561 0.779 rs78589800 chr6:25883500 C/G cg17042849 chr6:26104293 HIST1H4C -0.78 -5.52 -0.44 1.92e-7 Iron status biomarkers; TGCT cis rs6496667 0.779 rs8039719 chr15:90958584 C/G cg20927724 chr15:90209326 PLIN1 0.34 4.76 0.39 5.26e-6 Rheumatoid arthritis; TGCT cis rs4727027 0.901 rs7794500 chr7:148819519 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 -0.51 -4.64 -0.38 8.88e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12682352 0.652 rs3789843 chr8:8724257 C/T cg17143192 chr8:8559678 CLDN23 0.46 4.66 0.39 7.92e-6 Neuroticism; TGCT cis rs7949030 0.653 rs17773169 chr11:62318530 G/T cg11742103 chr11:62369870 EML3;MTA2 0.62 8.97 0.63 3.88e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9291683 0.595 rs13150928 chr4:10052961 G/T cg00071950 chr4:10020882 SLC2A9 0.67 8.42 0.6 7.8500000000000006e-14 Bone mineral density; TGCT cis rs11105298 0.838 rs10858862 chr12:89842053 T/C cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs4253772 0.744 rs1134224 chr22:46633371 A/T cg09491104 chr22:46646882 C22orf40 -0.48 -4.84 -0.4 3.71e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs769267 0.930 rs2301786 chr19:19413947 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs3741151 1.000 rs79794992 chr11:73049352 A/G cg17517138 chr11:73019481 ARHGEF17 1.21 6.34 0.49 3.83e-9 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT trans rs208520 1.000 rs12191403 chr6:66978137 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs10791323 0.569 rs2156680 chr11:133742292 T/G cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs875971 0.660 rs7807930 chr7:66087165 C/T cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs12210905 0.688 rs72845031 chr6:27535404 C/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs686320 1.000 rs1787666 chr11:65249089 A/C cg21890820 chr11:65308645 LTBP3 0.59 4.71 0.39 6.49e-6 Hip circumference adjusted for BMI; TGCT cis rs17376456 0.825 rs72786702 chr5:93254656 A/C cg21475434 chr5:93447410 FAM172A 0.65 4.5 0.37 1.57e-5 Diabetic retinopathy; TGCT cis rs114540395 0.925 rs17696674 chr10:103415063 A/T cg18276125 chr10:102749041 C10orf2 0.41 4.79 0.39 4.73e-6 Schizophrenia; TGCT cis rs7209700 0.963 rs1000232 chr17:45356561 T/C cg17185639 chr17:45330862 ITGB3 0.18 4.52 0.38 1.4e-5 IgG glycosylation; TGCT cis rs2562456 0.917 rs2650804 chr19:21680184 A/G cg25650185 chr19:21324782 ZNF431 -0.61 -5.28 -0.43 5.64e-7 Pain; TGCT cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg20999797 chr1:1681921 NA 0.18 4.61 0.38 1.01e-5 Body mass index; TGCT cis rs2742417 0.603 rs6807438 chr3:45778623 G/A cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9467711 0.606 rs9393710 chr6:26367833 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9653442 0.835 rs11694875 chr2:100732845 A/G cg07810366 chr2:100720526 AFF3 0.47 7.99 0.58 7.99e-13 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6725041 0.757 rs9973677 chr2:213080994 C/T cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs916888 0.773 rs199451 chr17:44801784 G/A cg17911788 chr17:44343683 NA -0.66 -6.85 -0.52 3.03e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg05148404 chr5:132700446 FSTL4 0.61 7.02 0.53 1.3e-10 Breast cancer; TGCT cis rs2050392 0.590 rs303433 chr10:30714963 A/T cg18806716 chr10:30721971 MAP3K8 -0.7 -9.36 -0.64 4.55e-16 Inflammatory bowel disease; TGCT cis rs739496 0.527 rs7136469 chr12:112348191 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs6540559 0.546 rs735693 chr1:210033988 A/C cg12034118 chr1:209979487 IRF6 0.69 4.9 0.4 2.93e-6 Cleft lip with or without cleft palate; TGCT cis rs72945132 0.882 rs55738915 chr11:70190019 C/T cg00319359 chr11:70116639 PPFIA1 0.98 7.24 0.55 4.12e-11 Coronary artery disease; TGCT cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg07424592 chr7:64974309 NA 1.22 7.36 0.55 2.2e-11 Diabetic kidney disease; TGCT cis rs12893668 0.572 rs35011804 chr14:104151400 C/T cg26031613 chr14:104095156 KLC1 -0.59 -5.05 -0.41 1.53e-6 Reticulocyte count; TGCT cis rs2342371 0.805 rs55997345 chr3:196218353 T/C cg15048948 chr3:196158458 UBXN7 0.53 4.49 0.37 1.6e-5 Fat distribution (HIV); TGCT cis rs1005277 0.579 rs1740745 chr10:38520056 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs11249608 0.548 rs13156530 chr5:178475017 C/T cg23951258 chr5:178450506 ZNF879 0.44 4.5 0.37 1.57e-5 Pubertal anthropometrics; TGCT cis rs10986311 0.832 rs10818952 chr9:127137803 T/C cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.8 -0.4 4.54e-6 Vitiligo; TGCT cis rs2243480 1.000 rs778679 chr7:65840911 A/G cg18252515 chr7:66147081 NA -1.22 -7.33 -0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs858239 0.600 rs10241208 chr7:23144914 G/C cg05602783 chr7:23145260 KLHL7 -0.73 -6.3 -0.49 4.74e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs6545883 0.929 rs6545877 chr2:61741947 T/C cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.42 7.06e-7 Tuberculosis; TGCT cis rs735396 1.000 rs2259816 chr12:121435587 A/C cg02403541 chr12:121454288 C12orf43 -0.66 -6.42 -0.5 2.59e-9 N-glycan levels; TGCT cis rs114540395 0.777 rs117932321 chr10:103149531 G/A cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs6582630 0.524 rs10785494 chr12:38532431 C/G cg26384229 chr12:38710491 ALG10B -0.53 -4.78 -0.39 4.9100000000000004e-06 Drug-induced liver injury (flucloxacillin); TGCT cis rs66573146 0.831 rs1048009 chr4:6988677 G/A cg05069807 chr4:6945702 TBC1D14 0.3 4.86 0.4 3.53e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7666738 0.830 rs13149346 chr4:99009933 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.519 rs4405392 chr12:38293661 A/C cg26384229 chr12:38710491 ALG10B 0.82 7.23 0.54 4.32e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs9394841 0.692 rs9394837 chr6:41848088 G/A cg08135965 chr6:41755394 TOMM6 0.54 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs1048238 0.545 rs848199 chr1:16292742 C/T cg21385522 chr1:16154831 NA -0.61 -6.83 -0.52 3.34e-10 Systolic blood pressure; TGCT cis rs9911578 0.935 rs2302189 chr17:56584205 A/C cg12560992 chr17:57184187 TRIM37 -0.74 -9.0 -0.63 3.27e-15 Intelligence (multi-trait analysis); TGCT cis rs694739 1.000 rs646153 chr11:64089588 C/T cg23796481 chr11:64053134 BAD;GPR137 0.69 7.12 0.54 7.69e-11 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg06481639 chr22:41940642 POLR3H -0.75 -6.67 -0.51 7.59e-10 Vitiligo; TGCT cis rs651907 0.535 rs34743741 chr3:101532448 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.43 0.68 1.13e-18 Colorectal cancer; TGCT cis rs78707713 0.560 rs17569412 chr10:71237536 C/A cg12610070 chr10:71211762 TSPAN15 -0.62 -7.31 -0.55 2.83e-11 Venous thromboembolism; TGCT cis rs3806843 0.838 rs2262567 chr5:140132134 T/A cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs6967414 0.786 rs6972017 chr7:6754034 A/G cg00387323 chr7:6746715 ZNF12 0.74 4.54 0.38 1.29e-5 Hematocrit;Hemoglobin concentration; TGCT cis rs7666738 0.830 rs13112037 chr4:98976986 A/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs546131 0.928 rs499183 chr11:34836678 A/G cg11058730 chr11:34937778 PDHX;APIP 0.52 4.58 0.38 1.13e-5 Lung disease severity in cystic fibrosis; TGCT cis rs17102423 0.559 rs3783720 chr14:65475411 A/G cg11161011 chr14:65562177 MAX -0.46 -5.38 -0.44 3.53e-7 Obesity-related traits; TGCT cis rs79911532 0.515 rs76760929 chr7:75625968 T/G cg24069840 chr7:75623858 TMEM120A 0.83 4.54 0.38 1.32e-5 Mononucleosis; TGCT cis rs7914558 0.966 rs10786724 chr10:104668942 A/G cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9902453 0.791 rs28492945 chr17:28223982 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.91 8.82 0.62 8.68e-15 Coffee consumption (cups per day); TGCT cis rs4242434 0.927 rs11778693 chr8:22462852 T/C cg03733263 chr8:22462867 KIAA1967 1.14 20.27 0.88 3.6e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7618915 0.547 rs4130905 chr3:52709831 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.47 -0.37 1.75e-5 Electroencephalogram traits; TGCT cis rs11719291 0.504 rs71324924 chr3:48865444 G/A cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 Cognitive function; TGCT cis rs3617 0.625 rs2240917 chr3:52851137 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.59 0.38 1.08e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs68170813 0.641 rs12532953 chr7:106865920 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs67311347 0.866 rs56331709 chr3:40356558 A/C cg13683864 chr3:40499215 RPL14 -0.92 -8.87 -0.62 6.51e-15 Renal cell carcinoma; TGCT cis rs3806843 0.576 rs246063 chr5:140324492 T/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs6840360 0.593 rs1429559 chr4:152681952 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.16 -0.42 9.49e-7 Intelligence (multi-trait analysis); TGCT cis rs2288073 0.965 rs10173173 chr2:24415461 G/T cg05570707 chr2:24270316 C2orf44 0.5 4.47 0.37 1.72e-5 Venous thromboembolism (SNP x SNP interaction); TGCT trans rs1005277 0.579 rs1985707 chr10:38434098 C/T cg27523141 chr10:43048294 ZNF37B 0.74 8.6 0.61 2.88e-14 Extrinsic epigenetic age acceleration; TGCT cis rs769267 1.000 rs7247309 chr19:19439631 A/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs700590 0.723 rs244761 chr5:88117027 A/T cg22951263 chr5:87985283 NA 0.55 5.33 0.43 4.45e-7 Educational attainment (years of education); TGCT trans rs4650994 0.507 rs2811312 chr1:178617603 A/G cg05059571 chr16:84539110 KIAA1609 0.51 9.76 0.66 4.88e-17 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6912958 0.781 rs1051148 chr6:88221892 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs6089584 0.627 rs13045575 chr20:60565596 G/A cg06108461 chr20:60628389 TAF4 -0.37 -4.46 -0.37 1.81e-5 Body mass index; TGCT cis rs7615952 0.800 rs2062773 chr3:125639648 T/C cg05084668 chr3:125655381 ALG1L -0.7 -5.74 -0.46 6.93e-8 Blood pressure (smoking interaction); TGCT cis rs9914544 0.564 rs11548434 chr17:18761508 G/A cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs11247915 0.600 rs12059495 chr1:26655614 A/G cg25392287 chr1:26333318 NA 0.22 4.55 0.38 1.28e-5 Obesity-related traits; TGCT cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg13695892 chr22:41940480 POLR3H 0.79 7.83 0.58 1.85e-12 Vitiligo; TGCT cis rs7666738 0.606 rs4699611 chr4:99097492 T/G cg05340658 chr4:99064831 C4orf37 0.42 4.49 0.37 1.62e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs941408 0.963 rs1640267 chr19:2789337 T/C cg06609049 chr19:2785107 THOP1 0.78 6.56 0.51 1.33e-9 Total cholesterol levels; TGCT cis rs4319547 0.695 rs10846746 chr12:122868696 C/T cg08088222 chr12:122070432 ORAI1 -0.25 -4.49 -0.37 1.58e-5 Body mass index; TGCT cis rs2307449 0.729 rs2529930 chr15:89881990 T/A cg24365117 chr15:89879190 POLG 0.33 4.75 0.39 5.58e-6 Menopause (age at onset); TGCT cis rs17376456 0.825 rs6865441 chr5:93284746 G/A cg25358565 chr5:93447407 FAM172A 1.03 8.1 0.59 4.5e-13 Diabetic retinopathy; TGCT cis rs3806843 0.576 rs246006 chr5:140339228 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs36051895 0.695 rs10974921 chr9:5024427 T/A cg02405213 chr9:5042618 JAK2 -0.75 -10.0 -0.67 1.23e-17 Pediatric autoimmune diseases; TGCT cis rs6589563 0.737 rs12274192 chr11:116652351 A/G cg20660624 chr11:117307972 DSCAML1 -0.38 -4.98 -0.41 2.09e-6 Eosinophil counts; TGCT cis rs10510102 0.872 rs12240308 chr10:123722922 C/A cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs7666738 0.830 rs13102369 chr4:99045912 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs1703755 0.527 rs12594633 chr15:42705464 A/C cg19009305 chr15:89181732 ISG20 0.53 6.89 0.53 2.5e-10 Fibrinogen levels; TGCT cis rs1062177 0.950 rs892005 chr5:151180621 A/G cg12924095 chr5:151150029 G3BP1 0.35 5.05 0.41 1.53e-6 Preschool internalizing problems; TGCT cis rs1801251 0.893 rs6733151 chr2:233592341 A/C cg08000102 chr2:233561755 GIGYF2 0.63 6.53 0.51 1.51e-9 Coronary artery disease; TGCT cis rs9443645 0.901 rs9448584 chr6:79572799 G/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs6570726 0.791 rs405206 chr6:145836873 C/A cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2997447 0.655 rs2275947 chr1:26383875 A/G cg19633962 chr1:26362018 EXTL1 -0.65 -4.84 -0.4 3.71e-6 QRS complex (12-leadsum); TGCT cis rs79149102 0.579 rs58645417 chr15:75325858 T/G cg09165964 chr15:75287851 SCAMP5 -1.07 -5.81 -0.46 4.93e-8 Lung cancer; TGCT cis rs17253792 0.555 rs17683626 chr14:56041112 G/T cg01858014 chr14:56050164 KTN1 -0.36 -4.57 -0.38 1.15e-5 Putamen volume; TGCT cis rs12946454 0.668 rs4792867 chr17:43249444 C/T cg10701640 chr17:43249399 NA 0.53 7.19 0.54 5.48e-11 Systolic blood pressure; TGCT cis rs6977660 0.714 rs4721824 chr7:19785898 A/G cg07541023 chr7:19748670 TWISTNB 0.81 4.46 0.37 1.81e-5 Thyroid stimulating hormone; TGCT cis rs3796352 1.000 rs6445557 chr3:53083969 C/T cg07884673 chr3:53033167 SFMBT1 -0.56 -6.15 -0.48 9.89e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3824867 0.920 rs7126210 chr11:47460306 A/G cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs73198271 0.740 rs964771 chr8:8650939 A/G cg06636001 chr8:8085503 FLJ10661 0.63 4.69 0.39 7.23e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9638182 0.720 rs13235543 chr7:73013901 C/T cg14087351 chr7:73037990 MLXIPL -0.65 -5.07 -0.41 1.43e-6 Triglycerides; TGCT cis rs12971120 0.947 rs3764509 chr18:72167124 C/G cg25817165 chr18:72167213 CNDP2 -0.29 -5.54 -0.45 1.71e-7 Refractive error; TGCT cis rs11673344 0.542 rs2562585 chr19:37509223 G/A cg08039142 chr19:36980659 ZNF566 0.52 4.92 0.4 2.68e-6 Obesity-related traits; TGCT cis rs9611519 0.567 rs8141730 chr22:41473061 A/G cg03806693 chr22:41940476 POLR3H -0.51 -4.57 -0.38 1.14e-5 Neuroticism; TGCT cis rs561655 0.629 rs10751134 chr11:85858887 G/A cg07180834 chr11:85838833 NA -0.32 -4.69 -0.39 7.19e-6 Alzheimer's disease (late onset); TGCT cis rs7819412 0.783 rs28722721 chr8:10948968 G/A cg27411982 chr8:10470053 RP1L1 -0.21 -4.56 -0.38 1.21e-5 Triglycerides; TGCT cis rs736408 0.608 rs2239547 chr3:52855229 T/C cg10802521 chr3:52805072 NEK4 -0.64 -6.51 -0.5 1.69e-9 Bipolar disorder; TGCT cis rs9952991 0.941 rs2542149 chr18:12779018 G/A cg23544223 chr18:12777786 NA 0.64 6.12 0.48 1.15e-8 Inflammatory skin disease; TGCT cis rs9303401 0.659 rs11495824 chr17:56918882 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs909674 0.662 rs2899318 chr22:39837625 A/G cg11247378 chr22:39784982 NA -0.72 -8.42 -0.6 7.79e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg16497277 chr3:49208875 KLHDC8B -0.55 -5.25 -0.43 6.4e-7 Menarche (age at onset); TGCT trans rs17685 0.697 rs28689051 chr7:75763624 G/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.35 0.6 1.11e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs308403 0.533 rs309377 chr4:123676353 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.83 12.14 0.74 7.98e-23 Blood protein levels; TGCT cis rs12458462 0.859 rs34242155 chr18:77425192 G/A cg11879182 chr18:77439856 CTDP1 0.68 7.74 0.57 3.03e-12 Monocyte count; TGCT cis rs28830936 0.535 rs28657602 chr15:41869162 G/A cg17847044 chr15:42102381 MAPKBP1 -0.19 -4.61 -0.38 9.9e-6 Diastolic blood pressure; TGCT cis rs17376456 0.825 rs13161885 chr5:93071242 A/C cg25358565 chr5:93447407 FAM172A 0.9 7.6 0.56 6.43e-12 Diabetic retinopathy; TGCT cis rs1008375 1.000 rs56974987 chr4:17627856 G/A cg10189774 chr4:17578691 LAP3 0.59 5.13 0.42 1.06e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4927850 1.000 rs7625570 chr3:195747398 A/G cg12923728 chr3:195709715 SDHAP1 -0.36 -7.49 -0.56 1.13e-11 Pancreatic cancer; TGCT cis rs2153535 0.580 rs9406143 chr6:8444583 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs3540 0.921 rs8034050 chr15:91000206 C/T cg22089800 chr15:90895588 ZNF774 0.75 6.94 0.53 1.92e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9653442 0.527 rs11690905 chr2:100761473 C/T cg22139774 chr2:100720529 AFF3 0.36 5.72 0.46 7.68e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3008870 0.920 rs975452 chr1:67480190 A/T cg08660285 chr1:67390436 MIER1;WDR78 1.08 11.47 0.72 3.32e-21 Lymphocyte percentage of white cells; TGCT cis rs539096 0.872 rs631248 chr1:44071221 C/T cg12908607 chr1:44402522 ARTN -0.51 -5.36 -0.43 3.83e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.920 rs2788654 chr1:76219569 C/T cg22875332 chr1:76189707 ACADM 0.69 8.32 0.6 1.32e-13 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2243480 1.000 rs36068983 chr7:65408991 C/T cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs7845219 0.544 rs2123647 chr8:95931782 A/G cg13393036 chr8:95962371 TP53INP1 0.43 5.03 0.41 1.67e-6 Type 2 diabetes; TGCT cis rs7291412 0.579 rs11090867 chr22:46454792 T/C cg05468064 chr22:46423449 NA 0.41 4.49 0.37 1.58e-5 Dupuytren's disease;Subjective well-being; TGCT trans rs208520 0.802 rs208496 chr6:66930786 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -9.95 -0.67 1.64e-17 Exhaled nitric oxide output; TGCT cis rs2204008 0.522 rs12370263 chr12:38113311 A/G cg26384229 chr12:38710491 ALG10B 0.84 7.61 0.56 6.06e-12 Bladder cancer; TGCT cis rs17270561 0.562 rs12199626 chr6:26013604 G/A cg17042849 chr6:26104293 HIST1H4C -0.83 -5.82 -0.46 4.74e-8 Iron status biomarkers; TGCT cis rs35306767 0.715 rs12772979 chr10:1034412 C/T cg20503657 chr10:835505 NA 0.63 6.97 0.53 1.64e-10 Eosinophil percentage of granulocytes; TGCT cis rs2880765 0.835 rs7180213 chr15:86021187 G/A cg13263323 chr15:86062960 AKAP13 -0.23 -4.97 -0.41 2.13e-6 Coronary artery disease; TGCT cis rs28595532 0.920 rs17325017 chr4:119774607 A/G cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs7267979 0.604 rs242130 chr20:25594020 C/A cg14121845 chr20:25566513 NINL -0.44 -4.57 -0.38 1.19e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11679640 1.000 rs73923006 chr2:43132224 G/C cg18281102 chr2:44065550 ABCG5;ABCG8 -0.27 -4.52 -0.38 1.45e-5 White matter hyperintensity burden; TGCT cis rs17221829 0.673 rs10765226 chr11:89385013 A/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.66 -0.39 7.89e-6 Anxiety in major depressive disorder; TGCT cis rs2637266 0.678 rs35278870 chr10:78471394 G/A cg18941641 chr10:78392320 NA 0.4 4.83 0.4 4e-6 Pulmonary function; TGCT cis rs4689592 0.513 rs4689586 chr4:7067413 A/G cg26116260 chr4:7069785 GRPEL1 1.13 11.1 0.71 2.59e-20 Monocyte percentage of white cells; TGCT cis rs9467711 0.591 rs6913795 chr6:25848025 T/C cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs4332037 1.000 rs62442899 chr7:1948454 C/T cg10840412 chr1:235813424 GNG4 1.05 8.28 0.6 1.71e-13 Bipolar disorder; TGCT cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT trans rs208520 0.874 rs208485 chr6:66925654 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.05 -0.67 9.41e-18 Exhaled nitric oxide output; TGCT cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.962 rs6089826 chr20:61668595 G/A cg18188782 chr20:61659543 NA 0.47 5.63 0.45 1.15e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs807669 0.527 rs11089259 chr22:19190143 C/T cg02655711 chr22:19163373 SLC25A1 0.32 6.44 0.5 2.38e-9 Metabolite levels; TGCT cis rs2249625 0.545 rs2496505 chr6:72891063 C/G cg08500200 chr6:72892038 RIMS1 -0.42 -4.55 -0.38 1.27e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs478304 0.654 rs10896029 chr11:65452952 C/T cg17480646 chr11:65405466 SIPA1 -0.63 -8.47 -0.61 6.08e-14 Acne (severe); TGCT cis rs3796352 1.000 rs4478072 chr3:53106125 G/T cg27565382 chr3:53032988 SFMBT1 0.44 4.82 0.4 4.11e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6429082 0.702 rs2131922 chr1:235705001 G/T cg26050004 chr1:235667680 B3GALNT2 -0.62 -5.68 -0.45 9.27e-8 Adiposity; TGCT cis rs2239547 0.522 rs9844736 chr3:52931971 T/G cg11645453 chr3:52864694 ITIH4 -0.38 -6.28 -0.49 5.25e-9 Schizophrenia; TGCT cis rs2075371 0.933 rs1868784 chr7:133945932 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.0 0.47 2.04e-8 Mean platelet volume; TGCT cis rs425277 0.583 rs3107151 chr1:2051513 T/G cg24578937 chr1:2090814 PRKCZ -0.25 -5.94 -0.47 2.68e-8 Height; TGCT cis rs826838 0.967 rs73096706 chr12:38860563 G/A cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT cis rs17253792 0.822 rs77544029 chr14:56087917 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg11845111 chr2:191398756 TMEM194B -0.36 -5.45 -0.44 2.59e-7 Pulse pressure; TGCT cis rs250677 0.958 rs10056942 chr5:148416114 C/A cg23229984 chr5:148520753 ABLIM3 0.21 4.81 0.4 4.35e-6 Breast cancer; TGCT cis rs7552404 0.924 rs1498317 chr1:76171984 A/C cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2404602 0.608 rs12911035 chr15:76606591 T/C cg26408565 chr15:76604113 ETFA -0.46 -6.46 -0.5 2.15e-9 Blood metabolite levels; TGCT cis rs2228479 0.850 rs17232910 chr16:89839766 G/C cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs7552404 0.590 rs1565717 chr1:76320441 T/C cg22875332 chr1:76189707 ACADM -0.58 -6.24 -0.49 6.18e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs208520 0.545 rs6899712 chr6:66749670 T/C cg07460842 chr6:66804631 NA 1.02 13.51 0.77 3.89e-26 Exhaled nitric oxide output; TGCT cis rs7147624 0.882 rs7141367 chr14:65938641 C/T cg03016385 chr14:66212404 NA -0.5 -7.18 -0.54 5.64e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs853679 0.517 rs4711164 chr6:28115156 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs9611565 0.765 rs132907 chr22:41801268 A/C cg06634786 chr22:41940651 POLR3H 0.73 6.81 0.52 3.84e-10 Vitiligo; TGCT cis rs40363 0.523 rs757270 chr16:3534451 C/T cg22508957 chr16:3507546 NAT15 -0.4 -4.51 -0.38 1.49e-5 Tuberculosis; TGCT cis rs2245368 0.523 rs67814714 chr7:76517422 T/C cg15770687 chr7:76625569 PMS2L11 0.35 4.53 0.38 1.36e-5 Body mass index in physically inactive individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction);BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs7819412 0.511 rs2409798 chr8:11435564 C/T cg06636001 chr8:8085503 FLJ10661 -0.76 -6.96 -0.53 1.71e-10 Triglycerides; TGCT cis rs933688 1.000 rs10041402 chr5:90738948 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.43 0.6 7.52e-14 Smoking behavior; TGCT cis rs6570726 0.764 rs76635693 chr6:145834070 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs2500448 chr20:25404027 A/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs858239 0.601 rs6962526 chr7:23158233 G/A cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1577917 1.000 rs34581302 chr6:86705948 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs7191700 0.511 rs243330 chr16:11350991 C/T cg00044050 chr16:11439710 C16orf75 0.82 8.3 0.6 1.46e-13 Multiple sclerosis; TGCT cis rs10875595 0.836 rs12187725 chr5:140662912 A/G cg20560182 chr5:140700478 TAF7 -0.67 -4.88 -0.4 3.15e-6 Pulmonary function decline; TGCT cis rs2303759 0.914 rs2288481 chr19:49878196 G/A cg22307029 chr19:49891270 CCDC155 0.54 5.03 0.41 1.7e-6 Multiple sclerosis; TGCT cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.92 7.33 0.55 2.53e-11 Platelet count; TGCT cis rs6952808 0.792 rs13224989 chr7:1953766 C/G cg22963979 chr7:1858916 MAD1L1 -0.34 -5.22 -0.42 7.3e-7 Bipolar disorder and schizophrenia; TGCT cis rs11030122 0.569 rs11030781 chr11:4083258 T/C cg18678763 chr11:4115507 RRM1 -0.46 -5.67 -0.45 9.61e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs11190604 0.767 rs3829162 chr10:102172752 T/G cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.5e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9486719 1.000 rs2472884 chr6:96863965 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs9818758 0.607 rs13068038 chr3:49294250 C/A cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4711336 1.000 rs3818523 chr6:33660371 G/A cg14003231 chr6:33640908 ITPR3 0.28 4.51 0.38 1.49e-5 Height; TGCT cis rs6964587 1.000 rs7805077 chr7:91644553 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs62103177 0.733 rs62096748 chr18:77619699 T/C cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs7208859 0.573 rs79505916 chr17:29062326 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 4.48 0.37 1.7e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs981844 0.848 rs17279789 chr4:154643245 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.07 0.59 5.09e-13 Response to statins (LDL cholesterol change); TGCT cis rs6450176 1.000 rs9687611 chr5:53300288 C/T ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7582180 0.627 rs4149523 chr2:101007039 T/C cg14675211 chr2:100938903 LONRF2 0.47 4.56 0.38 1.22e-5 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.846 rs372904 chr6:145887425 T/C cg23711669 chr6:146136114 FBXO30 0.85 9.24 0.64 8.9e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4713118 0.662 rs13218430 chr6:28029837 T/C cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs3020736 0.500 rs8143153 chr22:42515637 G/C cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.765 rs2309520 chr2:99570477 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.75 7.54 0.56 8.63e-12 Chronic sinus infection; TGCT cis rs319204 0.798 rs640653 chr5:146287125 G/A cg25021259 chr5:146258546 PPP2R2B 0.36 4.5 0.37 1.57e-5 Schizophrenia; TGCT cis rs509477 0.811 rs12964519 chr18:32583580 T/G cg23791764 chr18:32556832 MAPRE2 0.55 4.56 0.38 1.19e-5 Cerebrospinal fluid AB1-42 levels; TGCT cis rs7666738 0.830 rs921521 chr4:98838339 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.34 0.43 4.23e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9443645 0.901 rs6912683 chr6:79543492 C/A cg05283184 chr6:79620031 NA -0.2 -4.51 -0.38 1.49e-5 Intelligence (multi-trait analysis); TGCT cis rs514406 0.505 rs12726160 chr1:53175099 A/G cg25767906 chr1:53392781 SCP2 -0.49 -5.52 -0.44 1.88e-7 Monocyte count; TGCT trans rs2727020 0.734 rs1164664 chr11:49295542 T/G cg15704280 chr7:45808275 SEPT13 0.67 6.8 0.52 4.02e-10 Coronary artery disease; TGCT cis rs6964587 1.000 rs6961928 chr7:91669808 C/T cg17063962 chr7:91808500 NA 0.89 9.7 0.66 6.83e-17 Breast cancer; TGCT cis rs12497850 0.931 rs7628719 chr3:48995487 C/T cg07636037 chr3:49044803 WDR6 0.96 10.39 0.68 1.45e-18 Parkinson's disease; TGCT cis rs2404602 0.735 rs1607017 chr15:76726465 G/T cg26408565 chr15:76604113 ETFA 0.38 4.5 0.37 1.56e-5 Blood metabolite levels; TGCT cis rs7085104 0.700 rs3740397 chr10:104592675 G/C cg04362960 chr10:104952993 NT5C2 0.58 5.12 0.42 1.12e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs6570726 0.791 rs6570695 chr6:145911286 C/A cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7524258 0.903 rs6577424 chr1:7292417 C/T cg07173049 chr1:7289937 CAMTA1 -0.32 -5.31 -0.43 4.88e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs9389248 0.690 rs6939543 chr6:135255143 A/G cg24558204 chr6:135376177 HBS1L -0.47 -4.87 -0.4 3.3e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs3749237 0.595 rs3870337 chr3:49557095 G/T cg02487422 chr3:49467188 NICN1 0.57 5.84 0.46 4.26e-8 Resting heart rate; TGCT cis rs7647973 1.000 rs62259944 chr3:49430883 G/A cg07636037 chr3:49044803 WDR6 -0.71 -5.69 -0.46 8.57e-8 Menarche (age at onset); TGCT cis rs854624 0.711 rs1608205 chr17:34336767 T/A cg02022384 chr17:34097390 MMP28 0.49 4.55 0.38 1.28e-5 Blood protein levels; TGCT cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg05738196 chr6:26577821 NA 0.86 10.52 0.69 6.75e-19 Intelligence (multi-trait analysis); TGCT cis rs3812831 0.695 rs10467349 chr13:114939441 A/G cg06611532 chr13:114900021 NA 0.35 6.41 0.5 2.77e-9 Schizophrenia; TGCT cis rs7914558 0.869 rs10883842 chr10:104941589 C/T cg04362960 chr10:104952993 NT5C2 0.61 5.45 0.44 2.6e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs634534 0.622 rs593525 chr11:65727799 T/C cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 5.18 0.42 8.63e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg02953382 chr22:24373134 LOC391322 -0.76 -6.17 -0.48 9.04e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs231513 0.906 rs1642611 chr17:41997712 T/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.03 -0.41 1.67e-6 Cognitive function; TGCT cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs244731 0.959 rs3105419 chr5:176551396 G/C cg06060754 chr5:176797920 RGS14 0.44 5.88 0.47 3.5e-8 Urate levels in lean individuals; TGCT cis rs1153858 0.621 rs1706824 chr15:45579948 C/T cg26924012 chr15:45694286 SPATA5L1 1.0 10.91 0.7 7.59e-20 Homoarginine levels; TGCT cis rs6952809 0.532 rs10227362 chr7:2456799 A/G cg23289794 chr7:2394357 EIF3B -0.84 -7.26 -0.55 3.79e-11 Multiple sclerosis; TGCT cis rs2282802 0.685 rs67813630 chr5:139623592 C/A cg01081189 chr5:139537190 NA 0.28 5.08 0.41 1.36e-6 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs6966322 chr7:65646754 A/G cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs10751667 0.560 rs7924794 chr11:962745 A/T cg06064525 chr11:970664 AP2A2 -0.34 -7.86 -0.58 1.63e-12 Alzheimer's disease (late onset); TGCT cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs4742903 1.000 rs7854630 chr9:106875277 A/C cg21169611 chr9:106856078 SMC2 -0.49 -4.49 -0.37 1.61e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs7666738 0.830 rs10031292 chr4:99056877 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.2 0.42 7.83e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7769051 0.522 rs3736725 chr6:133095172 A/G cg22852734 chr6:133119734 C6orf192 1.16 4.48 0.37 1.67e-5 Type 2 diabetes nephropathy; TGCT cis rs36051895 0.589 rs12682672 chr9:5187941 T/C cg02405213 chr9:5042618 JAK2 -0.74 -9.56 -0.65 1.48e-16 Pediatric autoimmune diseases; TGCT cis rs2456568 0.802 rs1395387 chr11:93639307 A/T cg14065697 chr11:93583672 C11orf90 -0.37 -4.55 -0.38 1.25e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs875971 0.862 rs778720 chr7:65846275 A/C cg11764359 chr7:65958608 NA -0.52 -4.84 -0.4 3.86e-6 Aortic root size; TGCT cis rs425277 1.000 rs55826501 chr1:2059143 G/A cg24578937 chr1:2090814 PRKCZ 0.32 7.65 0.57 4.86e-12 Height; TGCT cis rs36051895 0.632 rs12352285 chr9:5141476 C/G cg02405213 chr9:5042618 JAK2 -0.74 -10.39 -0.68 1.4e-18 Pediatric autoimmune diseases; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg04234412 chr22:24373322 LOC391322 0.92 8.61 0.61 2.85e-14 S-phenylmercapturic acid levels in smokers; TGCT cis rs73198271 0.628 rs11783944 chr8:8597801 A/G ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.21 -0.42 7.61e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7584330 0.868 rs7569197 chr2:238383073 A/G cg16989719 chr2:238392110 NA -0.26 -4.48 -0.37 1.7e-5 Prostate cancer; TGCT cis rs7428 0.527 rs7608892 chr2:85542718 G/A cg24342717 chr2:85555507 TGOLN2 -0.49 -8.1 -0.59 4.49e-13 Ear protrusion; TGCT cis rs10501293 0.828 rs17497596 chr11:43102898 A/G cg03447554 chr11:43094025 NA 0.44 5.84 0.46 4.27e-8 Cognitive performance; TGCT cis rs909674 0.818 rs5757680 chr22:39844793 C/T cg05872129 chr22:39784769 NA 0.97 9.64 0.65 9.27e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9291683 0.530 rs998675 chr4:9948829 A/G cg00071950 chr4:10020882 SLC2A9 0.68 8.47 0.61 6.04e-14 Bone mineral density; TGCT cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2032447 0.714 rs199739 chr6:25960509 A/C cg12310025 chr6:25882481 NA -0.73 -6.73 -0.52 5.7e-10 Intelligence (multi-trait analysis); TGCT cis rs422249 0.512 rs174574 chr11:61600342 A/C cg20584555 chr11:61717780 BEST1 0.23 4.47 0.37 1.74e-5 Trans fatty acid levels; TGCT cis rs77972916 0.561 rs17406174 chr2:43557484 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.46 -0.37 1.78e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs7582180 0.652 rs11687864 chr2:100946993 T/A cg14675211 chr2:100938903 LONRF2 0.52 4.94 0.41 2.5e-6 Intelligence (multi-trait analysis); TGCT cis rs3793917 1.000 rs3793917 chr10:124219275 C/G cg09507567 chr10:124027408 NA 0.39 4.65 0.39 8.42e-6 Age-related macular degeneration; TGCT cis rs6728642 1.000 rs57035274 chr2:97608124 C/A cg26665480 chr2:98280029 ACTR1B -0.91 -5.37 -0.43 3.77e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs8032315 1.000 rs8032315 chr15:91418297 A/T cg05211768 chr15:91427848 FES 0.46 4.97 0.41 2.19e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6088580 0.634 rs1890000 chr20:32968312 G/T cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs13326165 0.760 rs11706001 chr3:52372128 T/A cg07884673 chr3:53033167 SFMBT1 0.39 4.67 0.39 7.85e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs4788815 1.000 rs4788815 chr16:71634811 A/T cg06353428 chr16:71660113 MARVELD3 0.58 5.1 0.42 1.25e-6 Metabolite levels; TGCT cis rs910316 0.967 rs175502 chr14:75533679 A/G cg23033748 chr14:75592666 NEK9 -0.28 -4.7 -0.39 6.67e-6 Height; TGCT trans rs7618501 1.000 rs3811696 chr3:49761605 C/T cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs72781680 0.898 rs72796158 chr2:23935727 T/C cg08917208 chr2:24149416 ATAD2B 0.89 5.41 0.44 3.11e-7 Lymphocyte counts; TGCT cis rs72634258 0.503 rs2794666 chr1:7822009 A/G cg26816564 chr1:7831052 VAMP3 0.94 6.65 0.51 8.5e-10 Inflammatory bowel disease; TGCT cis rs6964587 1.000 rs7784248 chr7:91758111 A/G cg22709100 chr7:91322751 NA 0.28 4.51 0.38 1.51e-5 Breast cancer; TGCT cis rs10225163 0.500 rs763746 chr7:27922780 A/G cg05786569 chr7:27702416 HIBADH 0.72 5.23 0.43 6.99e-7 Gout; TGCT cis rs4563143 0.675 rs112383987 chr19:29261081 C/T cg12756686 chr19:29218302 NA 0.77 6.61 0.51 1.01e-9 Methadone dose in opioid dependence; TGCT cis rs4665809 1.000 rs4665305 chr2:26313524 C/T cg22920501 chr2:26401640 FAM59B -0.73 -6.28 -0.49 5.18e-9 Gut microbiome composition (summer); TGCT cis rs1975974 0.872 rs17052352 chr17:21721972 A/G cg18423549 chr17:21743878 NA -0.53 -5.13 -0.42 1.1e-6 Psoriasis; TGCT cis rs4665809 0.627 rs13032756 chr2:26489730 A/T cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs12510870 0.634 rs6446941 chr4:74390516 C/T cg05868023 chr4:75230803 EREG 0.55 4.7 0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs7412746 0.611 rs1889741 chr1:150869045 T/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs9300255 0.679 rs12817892 chr12:123728702 G/A cg00376283 chr12:123451042 ABCB9 -0.75 -5.13 -0.42 1.07e-6 Neutrophil percentage of white cells; TGCT cis rs7586879 0.616 rs876186 chr2:25125585 C/T cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs16837677 0.826 rs76114442 chr1:156699977 G/A cg17331738 chr1:156647236 NES 0.75 4.91 0.4 2.77e-6 Sjögren's syndrome; TGCT trans rs459571 0.629 rs441233 chr9:136876021 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 0.89 10.67 0.69 2.92e-19 Platelet distribution width; TGCT cis rs7208859 0.623 rs9914242 chr17:29216245 G/T cg18442181 chr17:29233375 C17orf42 -0.8 -4.78 -0.39 4.86e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6987853 0.966 rs2974338 chr8:42391945 A/G cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs7666738 0.791 rs6833691 chr4:98951508 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs8017423 0.967 rs59980414 chr14:90687738 G/C cg04374321 chr14:90722782 PSMC1 0.76 7.85 0.58 1.67e-12 Mortality in heart failure; TGCT cis rs6964587 1.000 rs10234290 chr7:91716951 T/C cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs7258465 0.931 rs1560119 chr19:18573675 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs13040088 1.000 rs12480117 chr20:61558274 G/A cg23096297 chr20:61557774 DIDO1 1.15 9.35 0.64 4.71e-16 Menopause (age at onset); TGCT cis rs3796352 1.000 rs60942590 chr3:53016421 G/A cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1461503 1.000 rs1461499 chr11:122843987 C/A cg27398637 chr11:122830231 C11orf63 -0.39 -4.75 -0.39 5.58e-6 Menarche (age at onset); TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg25151919 chr3:44754333 ZNF502 -0.47 -5.44 -0.44 2.78e-7 Depressive symptoms; TGCT trans rs916888 0.773 rs538628 chr17:44787313 G/C cg22433210 chr17:43662623 NA 1.06 7.29 0.55 3.2e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2243480 1.000 rs6460260 chr7:65215455 T/C cg07424592 chr7:64974309 NA -1.33 -7.99 -0.58 7.81e-13 Diabetic kidney disease; TGCT cis rs5769765 0.837 rs8142737 chr22:50291889 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.73 -0.73 7.59e-22 Schizophrenia; TGCT cis rs10114408 0.959 rs7856998 chr9:96642245 G/A cg13679303 chr9:96623674 NA -0.35 -4.45 -0.37 1.85e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6542838 0.553 rs6739503 chr2:99537295 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.44 -0.44 2.74e-7 Fear of minor pain; TGCT cis rs28595532 1.000 rs115965820 chr4:119586485 G/A cg21605333 chr4:119757512 SEC24D 1.33 7.98 0.58 8.3e-13 Cannabis dependence symptom count; TGCT cis rs9311474 0.659 rs1133415 chr3:52575831 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.7 -0.39 6.7e-6 Electroencephalogram traits; TGCT trans rs7824557 0.569 rs2409718 chr8:11012977 C/T cg06636001 chr8:8085503 FLJ10661 -0.8 -7.49 -0.56 1.13e-11 Retinal vascular caliber; TGCT cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs9733 0.519 rs7521898 chr1:150707596 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs11785400 0.793 rs4467920 chr8:143736846 C/T cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs9467773 1.000 rs6922824 chr6:26553815 C/G cg15659132 chr6:26577336 NA -0.88 -12.88 -0.76 1.29e-24 Intelligence (multi-trait analysis); TGCT cis rs2228479 0.850 rs62054601 chr16:89811751 C/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg10263370 chr3:44754102 ZNF502 -0.43 -5.19 -0.42 8.5e-7 Depressive symptoms; TGCT cis rs12510870 0.599 rs10021827 chr4:74451734 T/A cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs797680 0.786 rs4847412 chr1:93829248 C/G cg17826107 chr1:92977322 EVI5 -0.24 -5.63 -0.45 1.13e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10782582 0.632 rs11810154 chr1:76239973 C/G cg10523679 chr1:76189770 ACADM -0.53 -4.99 -0.41 1.98e-6 Daytime sleep phenotypes; TGCT cis rs9894429 0.646 rs12603868 chr17:79618834 G/C cg18240062 chr17:79603768 NPLOC4 0.56 4.88 0.4 3.15e-6 Eye color traits; TGCT cis rs10464366 0.544 rs4540324 chr7:39185299 G/C cg15212455 chr7:39170539 POU6F2 0.3 6.73 0.52 5.66e-10 IgG glycosylation; TGCT cis rs12477438 0.520 rs6739579 chr2:99731552 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT trans rs2078543 0.616 rs62404669 chr6:22035821 T/C cg07692489 chr16:8960972 CARHSP1 -0.39 -6.64 -0.51 8.88e-10 Pulmonary function (smoking interaction); TGCT cis rs6089829 0.962 rs2277768 chr20:61666823 T/C cg08045932 chr20:61659980 NA 0.48 9.47 0.65 2.46e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs860554 0.546 rs1543805 chr1:201292794 A/G cg01022117 chr1:201258280 PKP1 -0.27 -4.93 -0.4 2.57e-6 Panic disorder; TGCT cis rs11122272 0.735 rs2790893 chr1:231508976 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.87e-11 Hemoglobin concentration; TGCT cis rs1005277 0.541 rs2505193 chr10:38394638 G/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9341808 0.718 rs9294171 chr6:80839815 C/T cg08355045 chr6:80787529 NA 0.32 5.87 0.47 3.78e-8 Sitting height ratio; TGCT cis rs453301 0.686 rs3989373 chr8:8911308 G/T cg08975724 chr8:8085496 FLJ10661 -0.54 -4.55 -0.38 1.25e-5 Joint mobility (Beighton score); TGCT cis rs3849570 0.922 rs3772895 chr3:81769493 A/G cg07356753 chr3:81810745 GBE1 -0.85 -8.17 -0.59 3.06e-13 Waist circumference;Body mass index; TGCT cis rs1799949 0.965 rs799912 chr17:41257134 T/C cg23758822 chr17:41437982 NA 0.66 6.68 0.51 7.12e-10 Menopause (age at onset); TGCT cis rs4700695 1.000 rs153389 chr5:65422729 C/T cg21114390 chr5:65439923 SFRS12 -0.65 -5.06 -0.41 1.47e-6 Facial morphology (factor 19); TGCT cis rs3087591 0.960 rs12945157 chr17:29603631 G/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.39 0.55 1.94e-11 Hip circumference; TGCT cis rs4072705 0.646 rs2416933 chr9:127245529 C/T cg13476313 chr9:127244764 NR5A1 -0.3 -5.01 -0.41 1.81e-6 Menarche (age at onset); TGCT cis rs7681440 0.647 rs4522832 chr4:90819391 A/C cg20003494 chr4:90757398 SNCA -0.53 -4.7 -0.39 6.75e-6 Dementia with Lewy bodies; TGCT cis rs319204 0.918 rs2436401 chr5:146287183 C/T cg25021259 chr5:146258546 PPP2R2B 0.36 4.5 0.37 1.57e-5 Schizophrenia; TGCT cis rs4478858 0.746 rs10798831 chr1:31688385 A/C cg00250761 chr1:31883323 NA 0.29 4.78 0.39 4.9e-6 Alcohol dependence; TGCT trans rs2727020 1.000 rs2727020 chr11:49111407 C/G cg15704280 chr7:45808275 SEPT13 0.7 7.57 0.56 7.56e-12 Coronary artery disease; TGCT cis rs7917772 0.582 rs729024 chr10:104341975 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs9733 0.596 rs2275236 chr1:150669952 A/G cg09365446 chr1:150670422 GOLPH3L -0.31 -4.64 -0.38 8.7e-6 Tonsillectomy; TGCT cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs3820928 0.904 rs59135978 chr2:227857763 T/C cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg16497277 chr3:49208875 KLHDC8B 0.53 4.92 0.4 2.71e-6 Menarche (age at onset); TGCT cis rs2228479 0.541 rs12918575 chr16:89811151 A/G cg04287289 chr16:89883240 FANCA 0.74 4.44 0.37 1.99e-5 Skin colour saturation; TGCT cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs911555 0.539 rs4374097 chr14:104072766 A/C cg26031613 chr14:104095156 KLC1 0.61 5.6 0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.694 rs11179394 chr12:38210389 A/G cg26384229 chr12:38710491 ALG10B -0.59 -5.19 -0.42 8.23e-7 Bladder cancer; TGCT cis rs2880765 0.835 rs2170735 chr15:86043485 G/A cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs13138063 chr4:99050438 A/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6088580 0.609 rs6059845 chr20:33036500 G/A cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs2404602 0.716 rs4079681 chr15:76695230 G/A cg26408565 chr15:76604113 ETFA -0.42 -5.44 -0.44 2.76e-7 Blood metabolite levels; TGCT trans rs1814175 0.817 rs7109440 chr11:49966296 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg27535305 chr1:53392650 SCP2 -0.28 -5.93 -0.47 2.85e-8 Monocyte count; TGCT cis rs4819052 1.000 rs9306123 chr21:46709922 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 5.49 0.44 2.17e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs736408 0.609 rs2230534 chr3:52802402 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.84 0.46 4.3e-8 Bipolar disorder; TGCT cis rs208520 0.690 rs12192851 chr6:66705862 G/C cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs875971 1.000 rs2087647 chr7:65593188 C/A cg18876405 chr7:65276391 NA -0.33 -5.02 -0.41 1.72e-6 Aortic root size; TGCT cis rs9611565 0.592 rs4822040 chr22:41963553 C/G cg13695892 chr22:41940480 POLR3H -0.83 -7.8 -0.57 2.16e-12 Vitiligo; TGCT cis rs9914544 0.545 rs35911764 chr17:18782582 C/T cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.06e-6 Educational attainment (years of education); TGCT cis rs10089 0.953 rs758179 chr5:127354424 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.71 6.22 0.49 6.97e-9 Ileal carcinoids; TGCT cis rs9549260 0.564 rs9577110 chr13:41271878 T/G cg21288729 chr13:41239152 FOXO1 0.87 8.2 0.59 2.57e-13 Red blood cell count; TGCT cis rs9611565 0.546 rs739134 chr22:42089623 T/C cg13695892 chr22:41940480 POLR3H 0.9 9.02 0.63 2.89e-15 Vitiligo; TGCT cis rs6558530 0.897 rs10481354 chr8:1704030 A/G cg09410841 chr8:1729607 CLN8 -0.86 -9.75 -0.66 5.24e-17 Systolic blood pressure; TGCT cis rs3733585 0.699 rs4515163 chr4:9959603 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6087990 0.806 rs4911257 chr20:31359574 T/C cg13636640 chr20:31349939 DNMT3B 1.02 12.15 0.74 7.56e-23 Ulcerative colitis; TGCT cis rs9527 0.501 rs12244388 chr10:104640052 G/A cg15744005 chr10:104629667 AS3MT -0.46 -5.77 -0.46 5.89e-8 Arsenic metabolism; TGCT cis rs763121 0.853 rs5757181 chr22:39013522 G/A cg06022373 chr22:39101656 GTPBP1 0.78 7.66 0.57 4.56e-12 Menopause (age at onset); TGCT cis rs74233809 1.000 rs74444347 chr10:104769275 A/C cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs644148 0.730 rs2571044 chr19:44985573 G/A cg15540054 chr19:45004280 ZNF180 -0.59 -4.5 -0.37 1.53e-5 Personality dimensions; TGCT cis rs3818285 0.556 rs2084607 chr10:111681411 C/T cg00817464 chr10:111662876 XPNPEP1 0.3 5.41 0.44 3.15e-7 Superior crus of antihelix expression; TGCT cis rs1903068 0.719 rs17711225 chr4:55999185 G/A cg01777861 chr4:56023843 NA 0.54 6.0 0.47 2.02e-8 Endometriosis; TGCT cis rs2236918 0.710 rs2797602 chr1:242029206 G/T cg04158730 chr1:242011433 EXO1 0.56 5.2 0.42 8.05e-7 Menopause (age at onset); TGCT trans rs1814175 0.817 rs10839358 chr11:49770972 G/A cg11707556 chr5:10655725 ANKRD33B -0.38 -7.76 -0.57 2.75e-12 Height; TGCT cis rs6918586 0.658 rs198822 chr6:26123539 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.69 -6.49 -0.5 1.87e-9 Schizophrenia; TGCT cis rs9926296 0.632 rs2011925 chr16:89814064 T/G cg04287289 chr16:89883240 FANCA 0.67 6.53 0.51 1.51e-9 Vitiligo; TGCT cis rs11578119 0.933 rs12724601 chr1:170427510 C/G cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs7216064 1.000 rs11079707 chr17:65835617 A/G cg12091567 chr17:66097778 LOC651250 0.82 6.39 0.5 3.04e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs78487399 0.808 rs17030998 chr2:43758199 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1008375 0.646 rs4235387 chr4:17569327 T/G cg18681998 chr4:17616180 MED28 0.83 7.55 0.56 8.11e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6088590 0.502 rs6059861 chr20:33068563 A/T cg06115741 chr20:33292138 TP53INP2 0.52 4.47 0.37 1.75e-5 Coronary artery disease; TGCT cis rs12497850 0.897 rs9850134 chr3:48957147 A/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs9467711 0.790 rs34158769 chr6:26336572 G/A cg16898833 chr6:26189333 HIST1H4D 1.2 5.52 0.44 1.87e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs7698623 0.717 rs1463094 chr4:88792584 G/A cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs2191566 0.960 rs6509133 chr19:44522913 A/G cg03039196 chr19:44506973 ZNF230 -0.52 -4.45 -0.37 1.87e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs7829975 0.514 rs2976929 chr8:8258712 T/C cg06636001 chr8:8085503 FLJ10661 0.69 6.02 0.48 1.81e-8 Mood instability; TGCT cis rs2652822 0.504 rs4619348 chr15:63359564 A/C cg12855773 chr15:63363890 TPM1 -0.17 -4.85 -0.4 3.62e-6 Metabolic traits; TGCT cis rs72945132 0.882 rs7121012 chr11:70214421 A/T cg00319359 chr11:70116639 PPFIA1 0.99 7.39 0.55 1.94e-11 Coronary artery disease; TGCT cis rs7088591 0.702 rs10491208 chr10:59703352 C/G cg00579859 chr10:60026291 IPMK 0.89 4.95 0.41 2.4e-6 Blood pressure; TGCT trans rs4332037 0.624 rs11766944 chr7:1888051 G/A cg10840412 chr1:235813424 GNG4 0.86 6.76 0.52 4.92e-10 Bipolar disorder; TGCT cis rs6089584 0.854 rs8117075 chr20:60613766 T/C cg13770153 chr20:60521292 NA -0.54 -6.99 -0.53 1.51e-10 Body mass index; TGCT cis rs7674212 0.539 rs6533056 chr4:104120997 T/C cg16532752 chr4:104119610 CENPE -0.6 -5.46 -0.44 2.51e-7 Type 2 diabetes; TGCT cis rs1862618 0.671 rs252897 chr5:56223000 G/A cg20203395 chr5:56204925 C5orf35 -0.57 -5.28 -0.43 5.6e-7 Initial pursuit acceleration; TGCT cis rs2439831 0.850 rs7183809 chr15:44120868 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs11690935 0.959 rs7355594 chr2:172639448 G/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs61935443 0.720 rs10859783 chr12:95285339 A/G cg21533806 chr12:95267307 NA 0.54 4.65 0.39 8.26e-6 Schizophrenia; TGCT cis rs910316 0.737 rs398896 chr14:75482827 C/A cg11812906 chr14:75593930 NEK9 -0.61 -5.66 -0.45 9.87e-8 Height; TGCT cis rs908922 0.676 rs4845789 chr1:152528100 A/G cg20991723 chr1:152506922 NA 0.45 6.06 0.48 1.55e-8 Hair morphology; TGCT cis rs67478160 0.595 rs1475007 chr14:104297147 A/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs11673344 0.503 rs7246720 chr19:37564628 C/T cg08039142 chr19:36980659 ZNF566 0.5 4.6 0.38 1.01e-5 Obesity-related traits; TGCT cis rs6582630 0.555 rs34145279 chr12:38405588 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.42 0.55 1.62e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs4319547 0.794 rs61954972 chr12:123074167 T/G cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.38 -0.44 3.5e-7 Body mass index; TGCT cis rs1218582 0.596 rs906595 chr1:154822907 C/T cg06221963 chr1:154839813 KCNN3 -0.55 -7.64 -0.57 5.13e-12 Prostate cancer; TGCT cis rs35306767 0.715 rs1871622 chr10:1049309 T/G cg20503657 chr10:835505 NA 0.61 6.71 0.52 6.11e-10 Eosinophil percentage of granulocytes; TGCT cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg23758822 chr17:41437982 NA 0.72 6.85 0.52 3.09e-10 Menopause (age at onset); TGCT cis rs478304 0.651 rs10896038 chr11:65505528 G/C cg27068330 chr11:65405492 SIPA1 -0.95 -9.64 -0.65 9.63e-17 Acne (severe); TGCT cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs4919687 0.550 rs17784294 chr10:104479385 G/T cg05855489 chr10:104503620 C10orf26 0.55 4.48 0.37 1.67e-5 Colorectal cancer; TGCT cis rs8180040 0.701 rs7617689 chr3:46996442 C/T cg27129171 chr3:47204927 SETD2 -0.71 -9.05 -0.63 2.45e-15 Colorectal cancer; TGCT cis rs7666738 0.791 rs7684521 chr4:99071219 A/G cg05340658 chr4:99064831 C4orf37 0.53 5.87 0.47 3.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 0.964 rs778721 chr7:65845397 C/G cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs10992471 0.535 rs10117041 chr9:95282331 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.63 -0.45 1.13e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3008870 0.959 rs2985816 chr1:67387750 G/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT cis rs2760061 0.545 rs1636196 chr1:228204030 A/G cg18477163 chr1:228402036 OBSCN 0.36 7.16 0.54 6.22e-11 Diastolic blood pressure; TGCT cis rs9916302 0.706 rs7503377 chr17:37708841 A/G cg03321784 chr17:37729644 NA 0.4 4.5 0.37 1.57e-5 Glomerular filtration rate (creatinine); TGCT trans rs6089829 0.888 rs4809465 chr20:61671156 G/C cg23505145 chr19:12996616 KLF1 0.96 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT trans rs208520 0.690 rs176289 chr6:66766522 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.0 -11.29 -0.71 9.4e-21 Exhaled nitric oxide output; TGCT cis rs13064411 0.518 rs2399480 chr3:113228599 T/C cg18753928 chr3:113234510 CCDC52 -0.56 -4.72 -0.39 6.3e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7829975 0.511 rs2976902 chr8:8341105 T/G cg06636001 chr8:8085503 FLJ10661 0.61 5.69 0.46 8.54e-8 Mood instability; TGCT cis rs2404602 0.735 rs11632222 chr15:76712927 C/G cg22467129 chr15:76604101 ETFA 0.52 5.5 0.44 2.05e-7 Blood metabolite levels; TGCT cis rs6840360 0.571 rs7695866 chr4:152488110 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs7572733 0.534 rs4850813 chr2:198775982 C/T cg00792783 chr2:198669748 PLCL1 -0.56 -5.11 -0.42 1.21e-6 Dermatomyositis; TGCT cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg03188948 chr7:1209495 NA 0.43 5.65 0.45 1.06e-7 Longevity;Endometriosis; TGCT cis rs11696501 0.688 rs6073848 chr20:44298550 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -8.71 -0.62 1.58e-14 Platelet count; TGCT cis rs7666738 0.791 rs13120773 chr4:98972589 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 0.802 rs851600 chr6:66893754 T/C cg07460842 chr6:66804631 NA -0.9 -9.37 -0.64 4.18e-16 Exhaled nitric oxide output; TGCT cis rs7208859 0.623 rs216446 chr17:28933718 T/G cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs55823223 0.564 rs936396 chr17:73846829 C/G cg08125733 chr17:73851984 WBP2 0.88 8.95 0.63 4.39e-15 Psoriasis; TGCT cis rs3771570 1.000 rs60209440 chr2:242260340 G/C cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs1008375 0.966 rs2191504 chr4:17675592 C/G cg10189774 chr4:17578691 LAP3 0.53 4.99 0.41 2e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs769267 0.896 rs10410664 chr19:19556651 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.65 5.4 0.44 3.25e-7 Tonsillectomy; TGCT cis rs10484885 0.878 rs55750696 chr6:90552336 G/A cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6681544 0.537 rs12074133 chr1:82385309 A/T cg04226724 chr1:82268649 LPHN2 0.47 4.95 0.41 2.33e-6 Metabolite levels (X-11787); TGCT cis rs3796352 1.000 rs13092352 chr3:52969697 C/T cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs73001065 1.000 rs56255430 chr19:19477877 A/C cg03709012 chr19:19516395 GATAD2A 1.03 4.96 0.41 2.23e-6 LDL cholesterol; TGCT cis rs7020830 0.861 rs13295981 chr9:37330067 C/T cg14294708 chr9:37120828 ZCCHC7 1.29 18.62 0.86 9.89e-38 Schizophrenia; TGCT cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 6.26 0.49 5.85e-9 Schizophrenia; TGCT cis rs9611565 0.592 rs5758406 chr22:42076641 A/G cg03806693 chr22:41940476 POLR3H 1.06 11.74 0.73 7.15e-22 Vitiligo; TGCT cis rs11096990 0.634 rs11947159 chr4:39288520 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs11031096 0.503 rs10835604 chr11:4109709 A/T cg18678763 chr11:4115507 RRM1 -0.47 -5.63 -0.45 1.17e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs10875746 0.768 rs12305182 chr12:48421407 G/T cg20731937 chr12:48336164 NA 0.69 5.83 0.46 4.46e-8 Longevity (90 years and older); TGCT cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs72945132 0.607 rs67767222 chr11:70121610 T/A cg00319359 chr11:70116639 PPFIA1 0.99 7.24 0.55 4.12e-11 Coronary artery disease; TGCT cis rs7027203 0.828 rs4344139 chr9:96600298 T/C cg14396892 chr9:96623032 NA -0.26 -5.46 -0.44 2.51e-7 DNA methylation (variation); TGCT cis rs1865760 0.566 rs1539183 chr6:26075051 G/C cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT trans rs2727020 0.681 rs1976901 chr11:49378697 T/C cg03929089 chr4:120376271 NA -0.74 -8.61 -0.61 2.73e-14 Coronary artery disease; TGCT cis rs12580194 0.593 rs61957937 chr12:55746850 G/C cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs9911578 0.835 rs1990008 chr17:56459408 C/G cg05425664 chr17:57184151 TRIM37 0.6 5.56 0.45 1.57e-7 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.825 rs17314797 chr5:93234845 T/A cg21475434 chr5:93447410 FAM172A 0.7 4.9 0.4 2.96e-6 Diabetic retinopathy; TGCT cis rs7572733 0.555 rs7600269 chr2:198923468 C/G cg00792783 chr2:198669748 PLCL1 0.59 5.15 0.42 1.01e-6 Dermatomyositis; TGCT cis rs2046867 0.862 rs62251656 chr3:72827393 T/C cg25664220 chr3:72788482 NA -0.54 -6.72 -0.52 5.82e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9733 0.525 rs11584184 chr1:150695689 A/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs2180341 0.883 rs9388568 chr6:127690694 C/A cg24812749 chr6:127587940 RNF146 0.92 7.43 0.55 1.55e-11 Breast cancer; TGCT cis rs7914558 1.000 rs8139 chr10:104848123 G/A cg15744005 chr10:104629667 AS3MT -0.37 -4.55 -0.38 1.28e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs707040 0.921 rs2037660 chr2:155232409 A/G cg18104148 chr2:154337490 NA -0.19 -4.63 -0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs7208859 0.623 rs73271869 chr17:29152221 G/A cg14008862 chr17:28927542 LRRC37B2 0.75 5.06 0.41 1.5e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9926296 0.581 rs2108838 chr16:89904426 A/G cg27121462 chr16:89883253 FANCA 0.64 6.14 0.48 1.05e-8 Vitiligo; TGCT cis rs7568458 0.837 rs35215812 chr2:85792384 G/A cg02493740 chr2:85810744 VAMP5 -0.27 -4.86 -0.4 3.53e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs8141529 0.702 rs5762870 chr22:29261159 C/T cg02153584 chr22:29168773 CCDC117 0.62 5.29 0.43 5.39e-7 Lymphocyte counts; TGCT cis rs6570726 0.935 rs369214 chr6:145856709 G/A cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3796352 0.568 rs11713376 chr3:52958927 A/G cg07884673 chr3:53033167 SFMBT1 0.47 4.81 0.4 4.32e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2228479 0.717 rs2074904 chr16:89811546 A/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7552404 0.924 rs1611823 chr1:76221706 T/G cg03433033 chr1:76189801 ACADM 0.75 8.76 0.62 1.19e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs151997 1.000 rs26063 chr5:50216718 G/A cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT trans rs9859260 0.744 rs557527 chr3:195780709 G/A cg17074656 chr11:63784126 MACROD1 0.53 6.75 0.52 4.98e-10 Mean corpuscular volume; TGCT cis rs6460942 0.778 rs17444259 chr7:12462428 C/T cg06484146 chr7:12443880 VWDE -0.52 -5.56 -0.45 1.55e-7 Coronary artery disease; TGCT trans rs4650994 0.905 rs12753251 chr1:178529898 G/A cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.37e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6840360 0.615 rs4696095 chr4:152467243 A/G cg17479576 chr4:152424074 FAM160A1 -0.71 -7.74 -0.57 2.95e-12 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg18765753 chr7:1198926 ZFAND2A -0.5 -5.96 -0.47 2.45e-8 Longevity;Endometriosis; TGCT cis rs554111 0.613 rs6699704 chr1:21241432 G/C cg01072550 chr1:21505969 NA 0.35 5.33 0.43 4.38e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs637571 0.780 rs677029 chr11:65683531 A/G cg26695010 chr11:65641043 EFEMP2 -0.46 -4.48 -0.37 1.65e-5 Eosinophil percentage of white cells; TGCT cis rs6840360 0.571 rs4696273 chr4:152528477 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs9646954 0.542 rs3828193 chr2:101031561 A/C cg14675211 chr2:100938903 LONRF2 -0.49 -4.64 -0.38 8.65e-6 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.817 rs9909128 chr17:28161482 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 7.95 0.58 9.99e-13 Coffee consumption (cups per day); TGCT cis rs11971779 0.680 rs11764236 chr7:139118514 C/T cg07862535 chr7:139043722 LUC7L2 0.66 5.07 0.41 1.42e-6 Diisocyanate-induced asthma; TGCT trans rs17685 0.712 rs7785025 chr7:75628101 C/T cg19862616 chr7:65841803 NCRNA00174 -0.5 -8.54 -0.61 4.11e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6933660 0.800 rs9383900 chr6:151782816 A/C cg10883421 chr6:151773342 RMND1;C6orf211 0.7 7.12 0.54 7.84e-11 Menarche (age at onset); TGCT cis rs10504229 0.595 rs77615399 chr8:58117394 C/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs1215050 0.755 rs2952911 chr4:98850666 T/C cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.18e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7267979 0.549 rs6138537 chr20:25184466 A/G cg03522245 chr20:25566470 NINL 0.45 4.54 0.38 1.3e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11122272 0.735 rs2739507 chr1:231527329 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.65 -6.23 -0.49 6.8e-9 Hemoglobin concentration; TGCT cis rs9473924 0.505 rs7746581 chr6:50853479 T/C cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg03452623 chr4:187889614 NA -0.36 -5.34 -0.43 4.32e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs986417 0.748 rs1955691 chr14:61004128 G/A cg27398547 chr14:60952738 C14orf39 1.49 10.43 0.68 1.12e-18 Gut microbiota (bacterial taxa); TGCT cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs514406 0.929 rs2607095 chr1:53325639 T/C cg25767906 chr1:53392781 SCP2 -0.53 -6.21 -0.49 7.34e-9 Monocyte count; TGCT cis rs2456568 0.802 rs7115629 chr11:93635477 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -6.44 -0.5 2.38e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs17401966 0.931 rs17034821 chr1:10414645 A/G cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs9894429 0.700 rs113915083 chr17:79552696 G/C cg18240062 chr17:79603768 NPLOC4 -0.85 -10.0 -0.67 1.28e-17 Eye color traits; TGCT cis rs7647973 1.000 rs13096474 chr3:49443081 C/T cg07690219 chr3:49449608 TCTA;RHOA 0.57 4.76 0.39 5.25e-6 Menarche (age at onset); TGCT cis rs8103278 0.740 rs2341097 chr19:46268902 C/T cg14061069 chr19:46274453 DMPK -0.43 -6.32 -0.49 4.29e-9 Coronary artery disease; TGCT cis rs254781 0.505 rs190438 chr5:88026902 C/T cg22951263 chr5:87985283 NA -0.57 -5.59 -0.45 1.4e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.649 rs139559 chr22:42191636 A/G cg06634786 chr22:41940651 POLR3H -0.76 -7.15 -0.54 6.74e-11 Vitiligo; TGCT cis rs597539 0.652 rs514296 chr11:68654182 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.3 0.6 1.46e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2295359 0.892 rs10889657 chr1:67615487 A/G cg03340356 chr1:67600835 NA 0.39 4.65 0.39 8.4e-6 Psoriasis; TGCT cis rs7100689 0.599 rs946892 chr10:82127551 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs7909670 0.716 rs7073882 chr10:12928571 C/G cg23097415 chr10:13391488 SEPHS1 0.49 4.62 0.38 9.32e-6 Height; TGCT cis rs9457247 1.000 rs406095 chr6:167409087 C/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs1005277 0.522 rs9418276 chr10:37940116 G/T cg25427524 chr10:38739819 LOC399744 -0.35 -7.04 -0.53 1.18e-10 Extrinsic epigenetic age acceleration; TGCT cis rs4851266 0.898 rs12994592 chr2:100857984 T/C cg22139774 chr2:100720529 AFF3 -0.32 -4.66 -0.39 7.89e-6 Educational attainment; TGCT cis rs3008870 1.000 rs2815352 chr1:67482104 A/G cg03991309 chr1:68237761 GNG12 0.27 4.49 0.37 1.6e-5 Lymphocyte percentage of white cells; TGCT cis rs7666738 0.830 rs7662199 chr4:99019766 G/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.65e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg13695892 chr22:41940480 POLR3H -0.87 -8.01 -0.58 6.94e-13 Vitiligo; TGCT cis rs3858526 0.959 rs10838797 chr11:5920977 A/G cg13902645 chr11:5959945 NA -0.44 -4.82 -0.4 4.19e-6 DNA methylation (variation); TGCT cis rs7829975 0.755 rs3789849 chr8:8687054 G/C cg08975724 chr8:8085496 FLJ10661 0.53 4.76 0.39 5.28e-6 Mood instability; TGCT cis rs78366141 0.649 rs76884708 chr4:89692043 G/C cg01026744 chr4:89619053 NAP1L5;HERC3 1.26 5.58 0.45 1.43e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs2836950 0.762 rs8134638 chr21:40644170 T/C cg06238570 chr21:40685208 BRWD1 -0.56 -5.59 -0.45 1.35e-7 Menarche (age at onset); TGCT cis rs6879260 0.928 rs11739624 chr5:179727290 T/C cg13944838 chr5:179740914 GFPT2 -0.38 -5.87 -0.47 3.7e-8 Height; TGCT cis rs10504229 1.000 rs66886949 chr8:58187613 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9399135 0.935 rs2150680 chr6:135347131 G/C cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg01585852 chr22:24235823 MIF -0.22 -4.69 -0.39 7.08e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6570726 0.791 rs1935612 chr6:145906090 T/A cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2242194 0.844 rs11264295 chr1:154987526 C/T cg16680214 chr1:154839983 KCNN3 -0.3 -5.53 -0.44 1.81e-7 Schizophrenia; TGCT cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg05985448 chr10:134359359 INPP5A 0.23 4.99 0.41 2.01e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs10504229 0.639 rs72650811 chr8:58115661 G/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg11845111 chr2:191398756 TMEM194B 0.37 5.65 0.45 1.03e-7 Pulse pressure; TGCT cis rs13217239 0.646 rs12201393 chr6:26975690 C/A cg07220782 chr6:26987966 LOC100270746;C6orf41 0.4 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs9653442 0.564 rs7593261 chr2:100789907 A/G cg07810366 chr2:100720526 AFF3 -0.35 -5.05 -0.41 1.51e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs13326165 0.760 rs34523877 chr3:52375711 T/C cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg08048268 chr3:133502702 NA -0.54 -7.2 -0.54 5.06e-11 Iron status biomarkers; TGCT cis rs9443645 0.869 rs9343848 chr6:79621101 C/T cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs56804039 0.524 rs4256595 chr8:8402264 A/T cg14215082 chr8:9055850 NA -0.48 -4.78 -0.39 4.86e-6 Cervical cancer; TGCT cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg04013166 chr16:89971882 TCF25 0.33 4.66 0.39 8.16e-6 Skin colour saturation; TGCT cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1371867 0.846 rs1660349 chr8:101319326 G/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs6450176 0.909 rs6884936 chr5:53293198 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs3087591 0.708 rs2525563 chr17:29647908 T/G cg24425628 chr17:29625626 OMG;NF1 0.39 5.74 0.46 6.74e-8 Hip circumference; TGCT cis rs2120019 0.505 rs77456790 chr15:75330095 G/T cg09165964 chr15:75287851 SCAMP5 -1.05 -5.56 -0.45 1.59e-7 Blood trace element (Zn levels); TGCT cis rs9650657 0.615 rs2271355 chr8:10692158 C/T cg16664915 chr8:10907788 XKR6 -0.31 -4.87 -0.4 3.31e-6 Neuroticism; TGCT cis rs9929218 0.953 rs16260 chr16:68771034 C/A cg01251360 chr16:68772225 CDH1 0.29 4.95 0.41 2.34e-6 Colorectal cancer; TGCT cis rs7306456 0.623 rs10902513 chr12:132693487 A/G cg02410480 chr12:132819930 GALNT9 -0.31 -4.63 -0.38 8.94e-6 Anti-saccade response; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.9 -0.4 2.97e-6 Prudent dietary pattern; TGCT cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs17155006 0.676 rs424866 chr7:107722869 T/C cg05962710 chr7:107745446 LAMB4 -0.19 -4.72 -0.39 6.19e-6 Pneumococcal bacteremia; TGCT cis rs611744 0.934 rs1989388 chr8:109220269 A/T cg21045802 chr8:109455806 TTC35 0.51 4.72 0.39 6.23e-6 Dupuytren's disease; TGCT cis rs61935443 0.614 rs11107787 chr12:95311669 C/T cg21533806 chr12:95267307 NA 0.57 4.75 0.39 5.43e-6 Schizophrenia; TGCT cis rs9894429 0.646 rs7405937 chr17:79597811 G/A cg21028142 chr17:79581711 NPLOC4 0.28 5.75 0.46 6.54e-8 Eye color traits; TGCT cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg06618935 chr21:46677482 NA -0.35 -5.39 -0.44 3.43e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2242116 0.932 rs7646906 chr3:46949379 G/A cg27129171 chr3:47204927 SETD2 0.63 6.19 0.49 8.22e-9 Birth weight; TGCT cis rs17001868 0.568 rs9611316 chr22:40737027 A/G cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs9486719 0.656 rs6924957 chr6:96853579 G/T cg06623918 chr6:96969491 KIAA0776 0.94 7.74 0.57 2.98e-12 Migraine;Coronary artery disease; TGCT cis rs13256369 0.951 rs10503394 chr8:8565775 A/G cg17143192 chr8:8559678 CLDN23 0.58 5.5 0.44 2.09e-7 Obesity-related traits; TGCT cis rs9733 0.544 rs2867302 chr1:150653650 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs7568458 0.905 rs10198569 chr2:85794415 C/T cg02493740 chr2:85810744 VAMP5 0.28 4.74 0.39 5.73e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1799949 1.000 rs8176145 chr17:41249094 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.79e-7 Menopause (age at onset); TGCT cis rs7267979 0.903 rs1118963 chr20:25247449 G/A cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs908922 0.676 rs578382 chr1:152514054 A/G cg20991723 chr1:152506922 NA -0.46 -6.43 -0.5 2.56e-9 Hair morphology; TGCT cis rs4566357 0.930 rs13398295 chr2:227926873 A/G cg11843606 chr2:227700838 RHBDD1 -0.5 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs4906332 1.000 rs35126287 chr14:103959432 A/G cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs2637266 1.000 rs12774835 chr10:78352226 C/G cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs6430585 0.591 rs724326 chr2:136485971 T/C cg07169764 chr2:136633963 MCM6 0.91 8.33 0.6 1.28e-13 Corneal structure; TGCT cis rs17221829 0.669 rs7128681 chr11:89383644 G/A cg02982614 chr11:89391479 FOLH1B -0.25 -4.44 -0.37 1.96e-5 Anxiety in major depressive disorder; TGCT cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg03264133 chr6:25882463 NA -0.97 -11.19 -0.71 1.6e-20 Uric acid levels; TGCT cis rs975739 0.695 rs1537067 chr13:78581501 A/G cg07847733 chr13:78271382 SLAIN1 0.49 4.45 0.37 1.88e-5 Hair color; TGCT cis rs11252926 0.527 rs10904093 chr10:436848 A/G cg13477178 chr10:375248 DIP2C 0.24 4.77 0.39 5.07e-6 Psychosis in Alzheimer's disease; TGCT cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg06481639 chr22:41940642 POLR3H 0.71 6.43 0.5 2.56e-9 Vitiligo; TGCT cis rs7772486 0.658 rs6570706 chr6:145962922 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7119 0.623 rs12905318 chr15:77845873 T/C cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg24549020 chr5:56110836 MAP3K1 0.67 5.67 0.45 9.57e-8 Initial pursuit acceleration; TGCT trans rs10504390 0.656 rs79932695 chr8:66547075 T/C cg18118147 chr19:51128640 SYT3 -0.77 -6.85 -0.52 2.99e-10 IgG glycosylation; TGCT cis rs17767294 0.614 rs11546572 chr6:28292662 T/C cg08851530 chr6:28072375 NA 1.61 6.99 0.53 1.5e-10 Parkinson's disease; TGCT cis rs9291683 0.609 rs13141233 chr4:10028729 T/C cg11266682 chr4:10021025 SLC2A9 0.66 9.54 0.65 1.61e-16 Bone mineral density; TGCT trans rs3107575 0.572 rs73169365 chr3:165319778 T/C cg15894581 chr15:63889406 FBXL22 0.88 6.83 0.52 3.32e-10 Morning vs. evening chronotype; TGCT cis rs2243480 1.000 rs6964245 chr7:65718717 G/A cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs2535633 0.602 rs6801235 chr3:53009595 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.2 -0.42 8.09e-7 Body mass index; TGCT cis rs12681287 0.752 rs4427148 chr8:87250668 G/A cg27223183 chr8:87520930 FAM82B -0.8 -5.67 -0.45 9.58e-8 Caudate activity during reward; TGCT cis rs9916302 0.706 rs9909304 chr17:37500508 G/T cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs66573146 1.000 rs67405518 chr4:6965930 C/T cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1371867 0.846 rs1788204 chr8:101303936 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs9647570 0.640 rs36098019 chr5:167269875 T/C cg11091196 chr5:167285540 ODZ2 -0.31 -4.62 -0.38 9.5e-6 Menarche (age at onset); TGCT cis rs7781977 0.960 rs4917017 chr7:50335232 A/G cg01139861 chr7:50343298 IKZF1 -0.55 -6.21 -0.49 7.48e-9 IgG glycosylation; TGCT cis rs7208859 0.623 rs8075163 chr17:29106310 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs739496 0.527 rs10849981 chr12:112335217 A/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7312933 0.618 rs6582390 chr12:42634586 C/T cg19980929 chr12:42632907 YAF2 0.42 6.04 0.48 1.66e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs854765 0.583 rs8065416 chr17:17851162 C/T cg09796270 chr17:17721594 SREBF1 0.23 4.45 0.37 1.92e-5 Total body bone mineral density; TGCT cis rs2115630 0.967 rs8027779 chr15:85255385 T/C cg24513567 chr15:85260248 SEC11A -0.34 -4.47 -0.37 1.76e-5 P wave terminal force; TGCT cis rs11627546 0.615 rs77201600 chr14:70366874 A/G cg10496350 chr14:71275911 MAP3K9 -0.89 -4.5 -0.37 1.52e-5 Red blood cell traits; TGCT cis rs17401966 0.540 rs7546368 chr1:10418826 G/A cg19773385 chr1:10388646 KIF1B -0.22 -5.05 -0.41 1.56e-6 Hepatocellular carcinoma; TGCT cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg17971929 chr21:40555470 PSMG1 -0.7 -6.56 -0.51 1.29e-9 Cognitive function; TGCT cis rs6693567 0.565 rs834235 chr1:150362154 C/T cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs7618915 0.547 rs35211965 chr3:52685305 C/G cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs9611565 0.765 rs727563 chr22:41867377 C/T cg03806693 chr22:41940476 POLR3H 1.02 11.05 0.7 3.59e-20 Vitiligo; TGCT cis rs10256972 0.591 rs10229680 chr7:1158565 C/T cg16145915 chr7:1198662 ZFAND2A -0.54 -7.02 -0.53 1.27e-10 Longevity;Endometriosis; TGCT cis rs12681287 0.517 rs68008113 chr8:87520894 C/A cg19078186 chr8:87526527 CPNE3 -0.36 -4.49 -0.37 1.59e-5 Caudate activity during reward; TGCT cis rs7095607 0.704 rs34869044 chr10:69953763 C/T cg18986048 chr10:69913749 MYPN 0.58 6.79 0.52 4.14e-10 Lung function (FVC); TGCT cis rs561341 0.800 rs7209766 chr17:30234848 T/A cg13647721 chr17:30228624 UTP6 0.61 4.73 0.39 5.89e-6 Hip circumference adjusted for BMI; TGCT cis rs7772486 0.754 rs697053 chr6:145989807 T/C cg05347473 chr6:146136440 FBXO30 -0.53 -4.97 -0.41 2.18e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12497850 0.866 rs6791234 chr3:48996137 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.5 0.44 2.06e-7 Parkinson's disease; TGCT cis rs7659604 1.000 rs35249024 chr4:122664538 C/A cg19748678 chr4:122722346 EXOSC9 0.57 5.54 0.45 1.69e-7 Type 2 diabetes; TGCT cis rs992157 0.764 rs2891079 chr2:219184691 A/G cg00012203 chr2:219082015 ARPC2 0.7 6.58 0.51 1.16e-9 Colorectal cancer; TGCT cis rs1552244 0.572 rs3894321 chr3:10168892 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs7681423 0.951 rs13130318 chr4:155538470 T/G cg20735720 chr4:155535218 FGG -0.44 -6.19 -0.49 8.27e-9 Fibrinogen; TGCT cis rs10927875 0.864 rs12744578 chr1:16173110 A/T cg21385522 chr1:16154831 NA -0.88 -10.64 -0.69 3.55e-19 Dilated cardiomyopathy; TGCT cis rs78487399 0.808 rs6752964 chr2:43754655 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9611519 0.566 rs4821981 chr22:41415644 A/C cg06634786 chr22:41940651 POLR3H 0.49 4.54 0.38 1.33e-5 Neuroticism; TGCT trans rs12599106 0.792 rs76039834 chr16:34598453 G/A cg21548813 chr6:291882 DUSP22 -0.65 -6.9 -0.53 2.41e-10 Menopause (age at onset); TGCT cis rs112998813 1.000 rs112998813 chr13:115059729 T/C cg24704211 chr13:115000206 CDC16 -0.98 -4.53 -0.38 1.36e-5 Nodular sclerosis Hodgkin lymphoma; TGCT cis rs4711336 0.935 rs3818525 chr6:33660779 A/G cg14003231 chr6:33640908 ITPR3 0.28 4.53 0.38 1.38e-5 Height; TGCT cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg23719950 chr11:63933701 MACROD1 -0.62 -5.33 -0.43 4.4e-7 Mean platelet volume; TGCT cis rs6089829 0.692 rs6122349 chr20:61664096 T/C cg08045932 chr20:61659980 NA 0.35 5.38 0.44 3.56e-7 Prostate cancer (SNP x SNP interaction); TGCT trans rs9650657 0.515 rs7820860 chr8:10950396 C/G cg15556689 chr8:8085844 FLJ10661 -0.85 -8.35 -0.6 1.14e-13 Neuroticism; TGCT cis rs1008375 0.931 rs10019482 chr4:17578079 G/A cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6089829 0.962 rs2872543 chr20:61665017 G/A cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg18538332 chr22:24372958 LOC391322 -1.01 -12.94 -0.76 9.13e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs644799 0.542 rs10831417 chr11:95467262 A/G cg03916912 chr11:95522834 CEP57;FAM76B -0.59 -6.01 -0.47 1.92e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7617773 0.817 rs3731513 chr3:48219537 A/G cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs4665809 1.000 rs10202478 chr2:26276049 T/C cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.36e-9 Gut microbiome composition (summer); TGCT cis rs12530845 1.000 rs12537555 chr7:135334061 G/A cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs950776 0.695 rs1878399 chr15:78912003 G/C cg06917634 chr15:78832804 PSMA4 -0.68 -5.41 -0.44 3.09e-7 Sudden cardiac arrest; TGCT cis rs2016266 0.859 rs4759061 chr12:53738214 C/T cg16917193 chr12:54089295 NA -0.7 -4.68 -0.39 7.49e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs10791323 0.569 rs10750552 chr11:133740141 A/C cg15485101 chr11:133734466 NA -0.38 -5.46 -0.44 2.52e-7 Childhood ear infection; TGCT cis rs7223966 0.921 rs34699959 chr17:61960720 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.68 5.32 0.43 4.68e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs72945132 0.882 rs113472486 chr11:70194945 C/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs4566357 1.000 rs4296417 chr2:227921941 G/A cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs713587 0.967 rs10865320 chr2:25159780 A/G cg01884057 chr2:25150051 NA 0.39 7.96 0.58 9.32e-13 Body mass index in non-asthmatics; TGCT cis rs9660992 0.573 rs12140703 chr1:205182865 G/C cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs28595532 0.841 rs56046449 chr4:119769302 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs2762353 0.574 rs4409177 chr6:25694491 T/G cg07061783 chr6:25882402 NA 0.75 7.46 0.56 1.3e-11 Blood metabolite levels; TGCT trans rs10506458 0.915 rs12424908 chr12:63402364 G/A cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs13242816 0.881 rs35062002 chr7:116142458 G/A cg02799643 chr7:116139180 CAV2 -0.42 -5.46 -0.44 2.45e-7 P wave duration; TGCT cis rs523522 0.962 rs11065145 chr12:120947419 A/G cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs12286929 0.687 rs6589487 chr11:115089927 T/C cg04017736 chr11:115827165 NA 0.18 4.47 0.37 1.78e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg01802117 chr1:53393560 SCP2 0.48 5.78 0.46 5.62e-8 Monocyte count; TGCT cis rs597539 0.652 rs646586 chr11:68681653 C/T cg04772025 chr11:68637568 NA -0.57 -6.38 -0.5 3.16e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13191362 0.938 rs28360532 chr6:162997477 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7020830 0.931 rs7034554 chr9:37081301 A/G cg14294708 chr9:37120828 ZCCHC7 1.29 20.57 0.88 8.69e-42 Schizophrenia; TGCT cis rs7312933 0.645 rs11181404 chr12:42683840 T/C cg19980929 chr12:42632907 YAF2 0.42 5.71 0.46 8.01e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7582180 0.614 rs9973737 chr2:100942296 T/C cg14675211 chr2:100938903 LONRF2 0.47 4.57 0.38 1.16e-5 Intelligence (multi-trait analysis); TGCT cis rs1401999 1.000 rs7632670 chr3:183713877 A/G cg01324343 chr3:183735012 ABCC5 0.83 11.23 0.71 1.3e-20 Anterior chamber depth; TGCT cis rs9733 0.596 rs11204687 chr1:150629880 C/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs12477438 0.798 rs13412764 chr2:99583733 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs473651 0.935 rs559579 chr2:239339501 G/C cg18131467 chr2:239335373 ASB1 0.95 9.87 0.66 2.62e-17 Multiple system atrophy; TGCT cis rs6964587 1.000 rs10270598 chr7:91700827 T/C cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs59107033 0.607 rs17295346 chr3:123126972 C/G cg04890266 chr3:123102914 ADCY5 -0.37 -5.36 -0.43 3.89e-7 Lymphocyte counts; TGCT cis rs16866061 1.000 rs12470077 chr2:225334971 T/C cg12698349 chr2:225449008 CUL3 0.96 9.57 0.65 1.4e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs2288073 0.965 rs6545340 chr2:24422269 C/G cg02683114 chr2:24398427 C2orf84 -0.25 -5.67 -0.45 9.72e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs6121246 0.559 rs6087771 chr20:30306724 A/G cg18721089 chr20:30220636 NA -0.36 -4.46 -0.37 1.83e-5 Mean corpuscular hemoglobin; TGCT cis rs10782582 0.593 rs74968421 chr1:76233496 T/C cg10523679 chr1:76189770 ACADM -0.61 -6.17 -0.48 8.87e-9 Daytime sleep phenotypes; TGCT cis rs1568889 0.838 rs7121937 chr11:28359858 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 10.85 0.7 1.1e-19 Bipolar disorder; TGCT cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.52 -5.85 -0.47 4.02e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs11741688 0.557 rs2004503 chr5:178337122 C/T cg09339527 chr5:178322752 ZFP2 -0.29 -4.96 -0.41 2.29e-6 Sleep duration; TGCT cis rs12477438 0.520 rs13031919 chr2:99848932 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 8.65 0.61 2.21e-14 Chronic sinus infection; TGCT cis rs7917772 0.503 rs1409310 chr10:104282265 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg23758822 chr17:41437982 NA 0.69 6.41 0.5 2.75e-9 Menopause (age at onset); TGCT cis rs611744 0.647 rs633901 chr8:109242981 G/T cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.44e-11 Dupuytren's disease; TGCT cis rs1110701 0.525 rs11764792 chr7:50496841 C/T cg18232548 chr7:50535776 DDC -0.38 -6.55 -0.51 1.37e-9 Acute lymphoblastic leukemia (childhood); TGCT cis rs3806843 0.548 rs246055 chr5:140325662 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs60843830 1.000 rs59937473 chr2:271797 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.73 7.29 0.55 3.23e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs6938 0.534 rs1127796 chr15:75193004 C/T cg09165964 chr15:75287851 SCAMP5 -0.55 -5.11 -0.42 1.16e-6 Breast cancer; TGCT cis rs896854 0.517 rs896851 chr8:95950251 T/C cg13393036 chr8:95962371 TP53INP1 -0.49 -5.65 -0.45 1.04e-7 Type 2 diabetes; TGCT cis rs892961 0.899 rs66749226 chr17:75412826 G/A cg05865280 chr17:75406074 SEPT9 0.29 6.93 0.53 1.99e-10 Airflow obstruction; TGCT cis rs9814567 1.000 rs13071551 chr3:134310867 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg06640241 chr16:89574553 SPG7 -0.76 -8.63 -0.61 2.45e-14 Multiple myeloma (IgH translocation); TGCT cis rs9894429 1.000 rs11651264 chr17:79576394 A/G cg18240062 chr17:79603768 NPLOC4 -0.67 -6.84 -0.52 3.23e-10 Eye color traits; TGCT cis rs904251 0.772 rs756202 chr6:37460350 C/A cg25019722 chr6:37503610 NA -0.44 -5.1 -0.42 1.21e-6 Cognitive performance; TGCT cis rs10931896 0.531 rs296801 chr2:201142812 C/T cg23649088 chr2:200775458 C2orf69 0.39 6.43 0.5 2.48e-9 Systolic blood pressure; TGCT cis rs2115630 0.645 rs3825877 chr15:85174631 G/A cg12863693 chr15:85201151 NMB -0.39 -5.11 -0.42 1.19e-6 P wave terminal force; TGCT cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs2762353 0.935 rs2817188 chr6:25807603 A/G cg12310025 chr6:25882481 NA -0.53 -5.45 -0.44 2.63e-7 Blood metabolite levels; TGCT cis rs8062405 0.895 rs56186137 chr16:28825953 A/G cg09754948 chr16:28834200 ATXN2L 0.62 4.69 0.39 6.95e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1865760 0.516 rs9393684 chr6:26075531 G/C cg17042849 chr6:26104293 HIST1H4C -0.66 -5.82 -0.46 4.73e-8 Height; TGCT cis rs10791097 0.694 rs6590520 chr11:130747386 C/G cg05962950 chr11:130786565 SNX19 0.92 11.5 0.72 2.77e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7829975 0.846 rs11779061 chr8:8549432 G/A cg15556689 chr8:8085844 FLJ10661 -0.71 -6.28 -0.49 5.27e-9 Mood instability; TGCT cis rs3785574 0.962 rs114027117 chr17:61939935 T/A cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.11 0.42 1.18e-6 Height; TGCT cis rs7586879 0.639 rs3903070 chr2:25123463 C/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs10927875 0.632 rs6677321 chr1:16149301 A/C cg21385522 chr1:16154831 NA -1.0 -17.61 -0.85 1.57e-35 Dilated cardiomyopathy; TGCT cis rs2361718 0.564 rs2304844 chr17:78084507 G/C cg22255288 chr17:78854418 RPTOR -0.25 -4.63 -0.38 9.09e-6 Yeast infection; TGCT cis rs3806843 0.966 rs10060640 chr5:140211226 G/A cg19875535 chr5:140030758 IK 0.35 5.51 0.44 1.94e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10464366 0.519 rs6974609 chr7:39219149 C/T cg15212455 chr7:39170539 POU6F2 0.29 6.08 0.48 1.4e-8 IgG glycosylation; TGCT cis rs34779708 0.931 rs11597483 chr10:35285117 A/G cg04310649 chr10:35416472 CREM -0.51 -4.55 -0.38 1.24e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs72945132 0.882 rs12278741 chr11:70135742 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs477895 0.653 rs3824854 chr11:63885305 C/T cg23719950 chr11:63933701 MACROD1 -0.72 -5.68 -0.45 9.11e-8 Mean platelet volume; TGCT cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs3008870 0.959 rs1886686 chr1:67390468 C/G cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs7192750 0.586 rs28697038 chr16:71952354 G/C cg06353428 chr16:71660113 MARVELD3 0.8 7.26 0.55 3.65e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7772486 0.875 rs1331645 chr6:146398407 C/G cg05347473 chr6:146136440 FBXO30 0.54 4.9 0.4 2.92e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7769051 1.000 rs9493444 chr6:133125320 C/G cg22852734 chr6:133119734 C6orf192 1.22 6.9 0.53 2.34e-10 Type 2 diabetes nephropathy; TGCT cis rs704795 0.836 rs1083865 chr2:27620827 A/G cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.46 -0.37 1.84e-5 Menopause (age at onset); TGCT cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs7267979 0.745 rs6132845 chr20:25547767 A/G cg03522245 chr20:25566470 NINL 0.58 6.07 0.48 1.47e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs597539 0.652 rs673821 chr11:68678718 G/T cg04772025 chr11:68637568 NA 0.59 6.66 0.51 8.15e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2153535 0.580 rs9378551 chr6:8463744 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs877282 1.000 rs12773872 chr10:771939 T/C cg17470449 chr10:769945 NA 0.31 4.89 0.4 3.03e-6 Uric acid levels; TGCT cis rs2836633 0.929 rs4143428 chr21:40030582 G/T cg12884169 chr21:40033163 ERG 0.42 4.54 0.38 1.34e-5 Coronary artery disease; TGCT cis rs9733 0.519 rs7529194 chr1:150622620 A/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.55 0.38 1.26e-5 Tonsillectomy; TGCT cis rs2153535 0.584 rs9502723 chr6:8541504 G/A cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.46e-7 Motion sickness; TGCT cis rs17401966 0.838 rs7553228 chr1:10350438 G/C cg19773385 chr1:10388646 KIF1B -0.21 -4.57 -0.38 1.17e-5 Hepatocellular carcinoma; TGCT cis rs7949030 0.626 rs11231141 chr11:62326265 T/C cg13298116 chr11:62369859 EML3;MTA2 0.64 9.45 0.65 2.73e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs854765 0.693 rs9915776 chr17:17749056 A/G cg09796270 chr17:17721594 SREBF1 -0.28 -5.44 -0.44 2.73e-7 Total body bone mineral density; TGCT cis rs709400 0.658 rs72708874 chr14:103899251 T/G cg12935359 chr14:103987150 CKB -0.36 -5.41 -0.44 3.09e-7 Body mass index; TGCT cis rs1577917 0.958 rs12202188 chr6:86562700 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs7917772 0.636 rs2249845 chr10:104512095 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.59 -4.86 -0.4 3.41e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4072705 0.900 rs4836993 chr9:127558370 G/C cg13476313 chr9:127244764 NR5A1 0.29 4.94 0.41 2.5e-6 Menarche (age at onset); TGCT cis rs6988636 1.000 rs57322232 chr8:124193532 A/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs1008375 0.932 rs13127157 chr4:17618049 A/G cg18681998 chr4:17616180 MED28 -0.98 -9.85 -0.66 2.99e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4662750 0.527 rs10164978 chr2:128385224 C/G cg01966334 chr2:128378434 MYO7B 0.2 4.62 0.38 9.66e-6 Renal cell carcinoma; TGCT cis rs12510870 0.729 rs11935001 chr4:74362091 G/T cg05868023 chr4:75230803 EREG 0.53 4.52 0.38 1.43e-5 Iris color (b* coordinate); TGCT cis rs644148 0.836 rs2571112 chr19:45000319 T/A cg15540054 chr19:45004280 ZNF180 -0.66 -5.36 -0.43 3.83e-7 Personality dimensions; TGCT trans rs561341 1.000 rs4795668 chr17:30244554 G/A cg20587970 chr11:113659929 NA -0.97 -11.47 -0.72 3.31e-21 Hip circumference adjusted for BMI; TGCT cis rs1580019 0.961 rs766660 chr7:32499077 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.7 0.57 3.71e-12 Cognitive ability; TGCT cis rs13242816 1.000 rs3807993 chr7:116197572 T/A cg02799643 chr7:116139180 CAV2 -0.41 -5.21 -0.42 7.65e-7 P wave duration; TGCT cis rs858239 0.539 rs2390757 chr7:23191492 A/G cg05602783 chr7:23145260 KLHL7 -0.68 -5.53 -0.44 1.79e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs79839061 0.610 rs3775130 chr4:875144 G/A cg07828340 chr4:882639 GAK 0.34 4.58 0.38 1.1e-5 Intelligence (multi-trait analysis); TGCT cis rs2677744 0.962 rs1266486 chr15:91460284 T/C cg22288577 chr15:91498497 RCCD1 0.49 5.23 0.42 7.11e-7 Attention deficit hyperactivity disorder; TGCT cis rs12477438 0.520 rs8179690 chr2:99795300 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.14 -17.24 -0.84 1.02e-34 Chronic sinus infection; TGCT cis rs76878669 0.917 rs10444359 chr11:66102807 G/A cg18002602 chr11:66138449 SLC29A2 -0.51 -5.71 -0.46 7.78e-8 Educational attainment (years of education); TGCT cis rs3008870 1.000 rs12740884 chr1:67459855 C/A cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs7581919 0.614 rs2287269 chr2:15650380 C/T cg19911430 chr2:16430654 NA -0.55 -4.58 -0.38 1.14e-5 Conduct disorder; TGCT cis rs13631 0.697 rs1018330 chr9:139980385 A/C cg03717367 chr9:139980219 LOC100289341;MAN1B1 0.25 4.52 0.38 1.45e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs7772486 0.875 rs7761033 chr6:146356106 C/T cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.690 rs552517 chr11:68625286 T/G cg21862992 chr11:68658383 NA 0.49 6.65 0.51 8.54e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1371867 0.846 rs1788204 chr8:101303936 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs9644630 0.897 rs13266857 chr8:19364515 C/T cg01280390 chr8:19363452 CSGALNACT1 -0.26 -4.63 -0.38 9.11e-6 Oropharynx cancer; TGCT cis rs1865760 0.588 rs9467658 chr6:26010881 T/G cg17042849 chr6:26104293 HIST1H4C -0.65 -5.78 -0.46 5.77e-8 Height; TGCT cis rs514406 0.861 rs1412706 chr1:53237721 G/A cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT trans rs3790455 0.610 rs1171554 chr1:156474119 G/A cg16443977 chr5:115884994 SEMA6A 0.4 6.97 0.53 1.66e-10 Migraine; TGCT cis rs9457247 0.508 rs9459874 chr6:167504127 A/G cg07741184 chr6:167504864 NA -0.27 -5.26 -0.43 6.17e-7 Crohn's disease; TGCT cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg13397359 chr6:42928475 GNMT -0.7 -6.52 -0.51 1.63e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg12756686 chr19:29218302 NA 0.77 6.61 0.51 1.01e-9 Methadone dose in opioid dependence; TGCT cis rs2404602 0.692 rs4383105 chr15:77055510 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg05985448 chr10:134359359 INPP5A 0.2 4.49 0.37 1.61e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9581857 0.547 rs9581869 chr13:28082498 G/A cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs1577917 0.958 rs1337843 chr6:86675545 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT trans rs66573146 1.000 rs6852613 chr4:7035637 G/A cg07817883 chr1:32538562 TMEM39B 1.63 8.26 0.6 1.86e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs11098499 0.754 rs10212714 chr4:120254302 T/C cg09307838 chr4:120376055 NA 0.62 5.95 0.47 2.5e-8 Corneal astigmatism; TGCT cis rs17122693 1.000 rs72679592 chr14:51094047 T/C cg04730355 chr14:51134070 SAV1 1.31 9.73 0.66 5.63e-17 Cognitive performance; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg12419862 chr22:24373484 LOC391322 -0.84 -9.35 -0.64 4.79e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9858542 0.953 rs6779524 chr3:49450449 C/T cg03060546 chr3:49711283 APEH -0.63 -5.49 -0.44 2.18e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs11112613 0.713 rs12307351 chr12:105955634 T/A cg03607813 chr12:105948248 NA 0.47 5.74 0.46 6.71e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs797680 0.856 rs6703310 chr1:93788740 A/C cg17826107 chr1:92977322 EVI5 -0.22 -5.09 -0.42 1.32e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs12477438 0.520 rs13023744 chr2:99738224 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.26 0.77 1.59e-25 Chronic sinus infection; TGCT cis rs778371 0.723 rs1022329 chr2:233591239 T/C cg08000102 chr2:233561755 GIGYF2 0.74 8.91 0.62 5.41e-15 Schizophrenia; TGCT cis rs6952808 0.531 rs3778991 chr7:2172455 G/A cg04267008 chr7:1944627 MAD1L1 -0.37 -4.97 -0.41 2.21e-6 Bipolar disorder and schizophrenia; TGCT cis rs248381 0.537 rs478651 chr5:78290682 A/G cg04677158 chr5:78279841 ARSB 0.28 5.4 0.44 3.32e-7 Toenail selenium levels; TGCT cis rs6750047 0.546 rs10192788 chr2:38272672 C/T cg07380506 chr2:38303506 CYP1B1 0.59 5.36 0.43 3.84e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs7223966 1.000 rs9912201 chr17:61763208 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.51 0.38 1.49e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs5758343 1 rs5758343 chr22:41816652 A/T cg13695892 chr22:41940480 POLR3H 0.94 8.92 0.63 5.1e-15 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2239547 0.657 rs13072536 chr3:52861211 A/T cg11645453 chr3:52864694 ITIH4 0.34 5.67 0.45 9.34e-8 Schizophrenia; TGCT cis rs6424115 1.000 rs34477640 chr1:24154067 T/C cg15997130 chr1:24165203 NA -0.92 -10.57 -0.69 5.26e-19 Immature fraction of reticulocytes; TGCT cis rs3820928 0.874 rs13385711 chr2:227830414 G/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs6815814 0.851 rs17582893 chr4:38886420 G/A cg02016764 chr4:38805732 TLR1 -0.34 -5.16 -0.42 9.63e-7 Breast cancer; TGCT cis rs11190604 1.000 rs7099913 chr10:102314777 T/C cg23241863 chr10:102295624 HIF1AN 0.71 5.4 0.44 3.26e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9902453 0.845 rs3102559 chr17:28029723 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs12188164 0.965 rs72717415 chr5:430059 G/A cg26850624 chr5:429559 AHRR -0.2 -4.81 -0.4 4.22e-6 Cystic fibrosis severity; TGCT cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg09222892 chr1:25734099 RHCE -0.41 -6.8 -0.52 3.99e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs4319547 0.656 rs10773075 chr12:122814236 G/A cg08088222 chr12:122070432 ORAI1 0.26 4.69 0.39 6.99e-6 Body mass index; TGCT cis rs950169 0.919 rs12915589 chr15:84734464 T/C cg17173187 chr15:85201210 NMB 0.47 5.23 0.42 7.11e-7 Schizophrenia; TGCT cis rs1865760 0.713 rs6928951 chr6:25995554 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 6.94 0.53 1.97e-10 Height; TGCT cis rs711245 0.670 rs7560321 chr2:36822318 C/G cg10546459 chr2:36825355 FEZ2 -0.56 -5.4 -0.44 3.34e-7 Height; TGCT cis rs13190036 0.901 rs28715668 chr5:176699268 T/C cg18465082 chr5:176734745 MXD3 -0.35 -4.54 -0.38 1.3e-5 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs1215050 0.791 rs13107606 chr4:98823187 C/A cg05340658 chr4:99064831 C4orf37 0.45 5.78 0.46 5.8e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs34779708 0.931 rs9663401 chr10:35278849 G/T cg04310649 chr10:35416472 CREM -0.51 -4.55 -0.38 1.24e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7172809 0.573 rs75180243 chr15:77649707 G/A cg22256960 chr15:77711686 NA -0.51 -4.81 -0.4 4.29e-6 Glucose homeostasis traits; TGCT cis rs367615 0.918 rs17161895 chr5:108855831 T/G cg17395555 chr5:108820864 NA 0.3 4.99 0.41 1.96e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7552404 0.731 rs11161845 chr1:76367559 T/C cg22875332 chr1:76189707 ACADM 0.7 6.84 0.52 3.26e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs651907 0.535 rs34743741 chr3:101532448 C/T cg12386194 chr3:101231763 SENP7 0.45 4.45 0.37 1.87e-5 Colorectal cancer; TGCT cis rs929354 0.772 rs6459739 chr7:156998863 A/T cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs7267979 1.000 rs2500418 chr20:25382268 C/T cg03522245 chr20:25566470 NINL -0.64 -7.05 -0.53 1.12e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4252435 0.520 rs7810229 chr7:142641087 A/G cg21621906 chr7:142494914 NA 1.08 4.53 0.38 1.36e-5 Cancer; TGCT cis rs6918586 0.658 rs198809 chr6:26128766 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.65 -6.2 -0.49 7.67e-9 Schizophrenia; TGCT cis rs12134133 1.000 rs2782840 chr1:207484183 C/T cg02152968 chr1:207494213 CD55 0.61 4.82 0.4 4.18e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs62064224 0.597 rs7207268 chr17:30725155 T/G cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.77e-6 Schizophrenia; TGCT cis rs9372498 0.536 rs9481833 chr6:118919631 G/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.13 -0.42 1.07e-6 Diastolic blood pressure; TGCT cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg08219700 chr8:58056026 NA 0.38 4.61 0.38 1e-5 Developmental language disorder (linguistic errors); TGCT cis rs67073037 0.868 rs11127193 chr2:29133121 G/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs12549902 0.966 rs6990613 chr8:41515130 A/G cg00088007 chr8:41504566 NKX6-3 0.36 5.56 0.45 1.6e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs7647973 0.588 rs4855848 chr3:49653457 C/T cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs3862030 0.839 rs2281880 chr10:104269217 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.53 -5.15 -0.42 9.99e-7 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs77741769 0.569 rs10774572 chr12:121309561 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT trans rs6089829 0.888 rs6011559 chr20:61675620 C/T cg23505145 chr19:12996616 KLF1 -0.97 -9.99 -0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7428 0.527 rs6547612 chr2:85551184 C/T cg24342717 chr2:85555507 TGOLN2 -0.49 -7.91 -0.58 1.21e-12 Ear protrusion; TGCT cis rs12541335 0.639 rs4565458 chr8:22154133 T/C cg07298985 chr8:22133076 PIWIL2 0.32 4.83 0.4 3.94e-6 Hypertriglyceridemia; TGCT cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg20999797 chr1:1681921 NA -0.2 -5.04 -0.41 1.61e-6 Body mass index; TGCT cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs10489525 0.560 rs10858062 chr1:115602563 A/G cg12756093 chr1:115239321 AMPD1 -0.4 -5.49 -0.44 2.19e-7 Autism; TGCT cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs826838 1.000 rs11168217 chr12:38884278 T/C cg26384229 chr12:38710491 ALG10B 1.04 10.43 0.68 1.11e-18 Heart rate; TGCT cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs9814567 0.752 rs4955468 chr3:134340850 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.72 -6.5 -0.5 1.78e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9297145 0.585 rs10953281 chr7:98772131 C/T cg05967295 chr7:98741636 SMURF1 -0.67 -8.42 -0.6 8e-14 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs1975974 0.511 rs56047890 chr17:21733405 G/A cg18423549 chr17:21743878 NA -0.65 -6.44 -0.5 2.36e-9 Psoriasis; TGCT cis rs13217239 0.646 rs10456351 chr6:26986792 C/T cg02458000 chr6:26745757 NA 0.5 4.61 0.38 9.84e-6 Schizophrenia; TGCT cis rs7119038 0.774 rs874621 chr11:118655645 G/A cg19308663 chr11:118741387 NA 0.31 6.13 0.48 1.06e-8 Sjögren's syndrome; TGCT cis rs734999 0.588 rs3748819 chr1:2524966 C/T cg18854424 chr1:2615690 NA 0.47 5.23 0.43 6.99e-7 Ulcerative colitis; TGCT cis rs9911578 1.000 rs12453459 chr17:56624291 C/T cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT trans rs916888 0.773 rs199447 chr17:44812188 C/T cg01341218 chr17:43662625 NA 1.11 9.15 0.63 1.43e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs2469997 0.858 rs2470031 chr8:120370390 T/A cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs3820068 0.705 rs6656907 chr1:15896984 A/G cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6490294 0.659 rs601663 chr12:112123284 A/G cg10833066 chr12:111807467 FAM109A 0.31 4.84 0.4 3.82e-6 Mean platelet volume; TGCT cis rs2795502 1.000 rs2744090 chr10:43339614 G/C cg20628663 chr10:43360327 NA -0.44 -6.37 -0.5 3.4e-9 Blood protein levels; TGCT cis rs7246657 0.943 rs10405325 chr19:37883477 G/C cg18154014 chr19:37997991 ZNF793 1.0 6.69 0.52 6.81e-10 Coronary artery calcification; TGCT cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg04608855 chr19:58913158 NA 0.54 5.16 0.42 9.58e-7 Uric acid clearance; TGCT cis rs7772486 0.720 rs702320 chr6:146006654 G/A cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs7635838 0.687 rs7625495 chr3:11377918 G/T cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs838147 0.537 rs632111 chr19:49208978 A/G cg13540341 chr19:49222985 MAMSTR -0.38 -5.06 -0.41 1.5e-6 Dietary macronutrient intake; TGCT cis rs9788682 1.000 rs7181447 chr15:78814567 A/G cg06917634 chr15:78832804 PSMA4 -0.71 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs853679 0.542 rs9380063 chr6:28137853 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs10791097 0.967 rs4366492 chr11:130717256 T/C cg05962950 chr11:130786565 SNX19 0.73 7.89 0.58 1.32e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2880765 0.835 rs4281668 chr15:86047286 C/T cg13263323 chr15:86062960 AKAP13 -0.21 -4.49 -0.37 1.63e-5 Coronary artery disease; TGCT cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 7.77 0.57 2.61e-12 Platelet count; TGCT cis rs7772486 0.719 rs2206141 chr6:146086192 A/G cg05347473 chr6:146136440 FBXO30 -0.53 -5.01 -0.41 1.84e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs72945132 0.660 rs12292191 chr11:70122426 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7267979 0.753 rs400357 chr20:25479058 A/G cg14121845 chr20:25566513 NINL 0.45 4.6 0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs637571 0.584 rs659824 chr11:65636509 A/G cg04055107 chr11:65626734 MUS81;CFL1 -0.63 -6.77 -0.52 4.65e-10 Eosinophil percentage of white cells; TGCT cis rs3733585 0.673 rs7377578 chr4:9952775 T/C cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6121246 0.567 rs6087701 chr20:30217708 A/C cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs4951018 0.821 rs7529037 chr1:205637501 C/G cg24503407 chr1:205819492 PM20D1 -0.36 -4.68 -0.39 7.53e-6 Prostate-specific antigen levels; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg20007245 chr22:24372913 LOC391322 0.74 6.69 0.52 6.72e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs709400 0.663 rs62007719 chr14:103943130 G/T cg12935359 chr14:103987150 CKB -0.37 -5.69 -0.46 8.55e-8 Body mass index; TGCT cis rs1800469 1.000 rs2241712 chr19:41869756 C/T cg09537434 chr19:41945824 ATP5SL -0.58 -5.23 -0.43 6.94e-7 Colorectal cancer; TGCT cis rs2354432 0.607 rs6685775 chr1:146744294 A/G cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs10883723 0.668 rs12414407 chr10:104387019 A/G cg05855489 chr10:104503620 C10orf26 0.51 4.53 0.38 1.35e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg11502198 chr6:26597334 ABT1 0.54 4.96 0.41 2.31e-6 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.543 rs4719436 chr7:2141239 G/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.41 -0.5 2.79e-9 Bipolar disorder and schizophrenia; TGCT cis rs17376456 0.569 rs11135394 chr5:93187135 C/T cg17533458 chr5:92956826 FAM172A;MIR2277 -0.53 -4.55 -0.38 1.24e-5 Diabetic retinopathy; TGCT cis rs67072384 1.000 rs61489692 chr11:72445314 T/C cg03713592 chr11:72463424 ARAP1 -0.9 -4.63 -0.38 9.26e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs17376456 0.569 rs12653528 chr5:93212833 T/C cg21475434 chr5:93447410 FAM172A -0.68 -5.22 -0.42 7.16e-7 Diabetic retinopathy; TGCT cis rs2120019 1.000 rs2120019 chr15:75334184 T/C cg11632617 chr15:75315747 PPCDC -0.3 -4.47 -0.37 1.71e-5 Blood trace element (Zn levels); TGCT cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs2070488 0.804 rs13092539 chr3:38458725 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.79 7.95 0.58 9.74e-13 Electrocardiographic conduction measures; TGCT cis rs10489202 0.608 rs10918826 chr1:168075316 C/T cg24449463 chr1:168025552 DCAF6 -0.53 -5.49 -0.44 2.16e-7 Schizophrenia; TGCT cis rs116095464 0.681 rs9687745 chr5:229309 C/T cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs9467773 1.000 rs9986382 chr6:26550619 T/C cg05738196 chr6:26577821 NA 0.91 13.11 0.76 3.53e-25 Intelligence (multi-trait analysis); TGCT cis rs3617 0.573 rs4687682 chr3:52916939 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.83 0.4 3.91e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs916888 0.610 rs199454 chr17:44800110 G/A cg01570182 chr17:44337453 NA -0.77 -7.45 -0.56 1.38e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs13082711 0.554 rs1494423 chr3:27375345 A/G cg02860705 chr3:27208620 NA -0.35 -5.05 -0.41 1.56e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7809950 0.678 rs2107317 chr7:106899685 T/C cg23024343 chr7:107201750 COG5 -0.43 -5.81 -0.46 4.86e-8 Coronary artery disease; TGCT cis rs7267979 1.000 rs34645895 chr20:25368373 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7091068 0.522 rs10882322 chr10:95483273 C/G cg20715218 chr10:95462985 C10orf4 0.5 4.86 0.4 3.49e-6 Urinary tract infection frequency; TGCT cis rs9611565 0.921 rs2281332 chr22:41746212 T/C cg17554472 chr22:41940697 POLR3H -0.4 -4.58 -0.38 1.11e-5 Vitiligo; TGCT cis rs1799949 0.965 rs11654051 chr17:41419656 C/T cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT trans rs561341 0.709 rs8068049 chr17:30183857 T/C cg20587970 chr11:113659929 NA 0.88 8.79 0.62 1.05e-14 Hip circumference adjusted for BMI; TGCT cis rs6750047 0.649 rs4670231 chr2:38267836 T/G cg07380506 chr2:38303506 CYP1B1 0.56 5.01 0.41 1.82e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg26354017 chr1:205819088 PM20D1 0.53 6.28 0.49 5.15e-9 Menarche (age at onset); TGCT cis rs10504229 0.679 rs73681882 chr8:58030038 A/G cg08280861 chr8:58055591 NA 0.35 5.01 0.41 1.85e-6 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.934 rs13149952 chr4:1308437 C/G cg03303774 chr4:1407052 NA 0.34 5.44 0.44 2.75e-7 Obesity-related traits; TGCT cis rs1933488 0.898 rs9479505 chr6:153415651 G/C cg24028809 chr6:153414101 RGS17 0.21 4.67 0.39 7.69e-6 Prostate cancer; TGCT cis rs4268898 0.722 rs12185638 chr2:24382030 C/G cg05570707 chr2:24270316 C2orf44 0.48 4.59 0.38 1.08e-5 Asthma; TGCT cis rs875971 0.965 rs9969301 chr7:65781655 G/A cg18876405 chr7:65276391 NA -0.32 -4.93 -0.4 2.63e-6 Aortic root size; TGCT trans rs6089829 0.962 rs4809455 chr20:61660781 G/C cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2637266 1.000 rs10824425 chr10:78340310 C/G cg18941641 chr10:78392320 NA 0.39 4.86 0.4 3.46e-6 Pulmonary function; TGCT cis rs733175 0.855 rs10016075 chr4:10006663 G/T cg11266682 chr4:10021025 SLC2A9 0.47 4.48 0.37 1.66e-5 Psychosis and Alzheimer's disease; TGCT cis rs2115630 1.000 rs55646601 chr15:85323568 G/T cg11189052 chr15:85197271 WDR73 -0.61 -5.89 -0.47 3.35e-8 P wave terminal force; TGCT cis rs2455799 0.559 rs4685267 chr3:15922992 C/T cg12172478 chr3:16357591 RFTN1 -0.34 -5.1 -0.42 1.23e-6 Mean platelet volume; TGCT cis rs10504229 0.512 rs117968470 chr8:58014651 C/G cg08219700 chr8:58056026 NA 0.37 4.48 0.37 1.71e-5 Developmental language disorder (linguistic errors); TGCT cis rs4820792 0.725 rs2347443 chr22:29119220 G/C cg03733026 chr22:29445468 ZNRF3 0.25 4.89 0.4 3.01e-6 Breast size; TGCT cis rs9902453 0.808 rs62068617 chr17:28144728 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.76e-11 Coffee consumption (cups per day); TGCT cis rs7659604 0.540 rs10020581 chr4:122676559 A/C cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs9911578 1.000 rs304270 chr17:56802141 A/G cg05425664 chr17:57184151 TRIM37 0.64 6.51 0.5 1.66e-9 Intelligence (multi-trait analysis); TGCT cis rs589448 0.933 rs2249093 chr12:69753512 G/C cg11871910 chr12:69753446 YEATS4 0.87 10.07 0.67 8.72e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs4700695 0.841 rs153367 chr5:65419170 G/A cg21114390 chr5:65439923 SFRS12 -0.59 -4.7 -0.39 6.79e-6 Facial morphology (factor 19); TGCT cis rs858239 0.669 rs6461688 chr7:23116615 G/A cg05407003 chr7:23246146 NA -0.31 -5.05 -0.41 1.54e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9914544 0.545 rs9912568 chr17:18792719 G/A cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg11644478 chr21:40555479 PSMG1 -0.57 -5.47 -0.44 2.41e-7 Menarche (age at onset); TGCT cis rs7666738 0.830 rs11731478 chr4:99001686 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.791 rs427128 chr6:145865917 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs629535 0.773 rs568159 chr8:70032908 C/G cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs7666738 0.546 rs10010088 chr4:98655945 C/T cg18180107 chr4:99064573 C4orf37 0.54 4.73 0.39 5.89e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg07061783 chr6:25882402 NA 0.66 6.75 0.52 4.99e-10 Blood metabolite levels; TGCT cis rs539096 0.715 rs6665014 chr1:44226004 G/T cg15962314 chr1:44399869 ARTN -0.32 -4.67 -0.39 7.78e-6 Intelligence (multi-trait analysis); TGCT cis rs4862750 0.872 rs6830828 chr4:187897472 T/G cg10295955 chr4:187884368 NA -1.02 -15.6 -0.81 5.02e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs9443645 0.901 rs1538233 chr6:79743735 G/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs7801950 chr7:116154783 C/T cg02799643 chr7:116139180 CAV2 -0.44 -5.54 -0.45 1.74e-7 P wave duration; TGCT cis rs28386778 0.897 rs2859619 chr17:61917686 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs9921338 0.961 rs4356497 chr16:11414196 C/G cg00044050 chr16:11439710 C16orf75 0.95 7.39 0.55 1.92e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4819052 0.851 rs2838836 chr21:46665875 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 4.99 0.41 1.98e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs644799 1.000 rs627568 chr11:95569253 A/C cg03916912 chr11:95522834 CEP57;FAM76B 0.88 9.67 0.66 8.05e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11785400 1.000 rs11776301 chr8:143737142 A/G cg24634471 chr8:143751801 JRK 0.6 6.5 0.5 1.75e-9 Schizophrenia; TGCT cis rs933688 1.000 rs186717 chr5:90780467 T/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.57 0.69 5.07e-19 Smoking behavior; TGCT cis rs2404602 0.716 rs8025134 chr15:76781729 C/T cg22467129 chr15:76604101 ETFA -0.55 -6.71 -0.52 6.16e-10 Blood metabolite levels; TGCT cis rs6785206 0.527 rs60684891 chr3:128638959 A/G cg25356066 chr3:128598488 ACAD9 -0.71 -4.45 -0.37 1.85e-5 Lymphocyte percentage of white cells; TGCT cis rs10256972 0.567 rs2960850 chr7:1211649 A/G cg17775962 chr7:1200435 ZFAND2A 0.28 4.51 0.38 1.51e-5 Longevity;Endometriosis; TGCT cis rs2073300 1.000 rs6137980 chr20:23466726 G/T cg09953122 chr20:23471693 CST8 -0.68 -4.7 -0.39 6.92e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7582180 0.614 rs6737217 chr2:101006267 T/G cg08017756 chr2:100939284 LONRF2 -0.31 -5.07 -0.41 1.4e-6 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.597 rs1970306 chr6:146154543 A/G cg05347473 chr6:146136440 FBXO30 0.66 6.2 0.49 7.84e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6429082 0.818 rs61836206 chr1:235638754 C/G cg26050004 chr1:235667680 B3GALNT2 0.57 4.95 0.41 2.41e-6 Adiposity; TGCT cis rs4460629 0.804 rs56112907 chr1:155070862 C/A cg23973274 chr1:155060172 NA -0.25 -4.64 -0.38 8.88e-6 Serum magnesium levels; TGCT cis rs11190604 1.000 rs2295774 chr10:102265847 A/C cg16342193 chr10:102329863 NA -0.41 -5.18 -0.42 8.61e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11690935 0.959 rs4667694 chr2:172605399 G/A cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs7811142 1.000 rs6975514 chr7:100056220 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs9807989 0.507 rs3755266 chr2:103042712 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs10791097 0.694 rs10894275 chr11:130756251 C/T cg12179176 chr11:130786555 SNX19 0.83 9.92 0.67 1.94e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12449000 1 rs12449000 chr16:89872970 T/C cg03388025 chr16:89894329 SPIRE2 0.5 8.11 0.59 4.19e-13 Schizophrenia; TGCT cis rs12989701 1.000 rs6710467 chr2:127889932 C/T cg08168897 chr2:127865431 BIN1 0.61 6.51 0.5 1.68e-9 Alzheimer's disease (late onset); TGCT cis rs2760061 0.583 rs1636195 chr1:228211589 T/C cg18477163 chr1:228402036 OBSCN 0.34 7.02 0.53 1.27e-10 Diastolic blood pressure; TGCT cis rs986417 0.901 rs10134736 chr14:60998540 A/T cg27398547 chr14:60952738 C14orf39 1.49 8.69 0.62 1.81e-14 Gut microbiota (bacterial taxa); TGCT cis rs7225537 0.559 rs4985721 chr17:16992544 C/A cg26176665 chr17:16994978 MPRIP 0.24 5.81 0.46 4.88e-8 Mean platelet volume; TGCT cis rs8020441 0.588 rs67977855 chr14:51184662 G/T cg04730355 chr14:51134070 SAV1 1.01 7.33 0.55 2.58e-11 Cognitive performance; TGCT cis rs2688608 0.933 rs2688614 chr10:75652876 G/A cg19442545 chr10:75533431 FUT11 -0.29 -4.63 -0.38 8.99e-6 Inflammatory bowel disease; TGCT cis rs12753569 0.748 rs1340689 chr1:76506409 T/A cg00791851 chr1:76518896 NA 0.34 4.46 0.37 1.8e-5 Personality dimensions; TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs9985766 1.000 rs28439804 chr4:151007375 G/A cg05926478 chr4:151174724 DCLK2 -0.26 -5.19 -0.42 8.26e-7 Coronary artery disease;Myocardial infarction; TGCT cis rs208520 0.526 rs7776413 chr6:66783241 A/G cg07460842 chr6:66804631 NA -1.08 -15.95 -0.82 8.03e-32 Exhaled nitric oxide output; TGCT cis rs1218582 0.774 rs11264284 chr1:154875793 C/T cg09359103 chr1:154839909 KCNN3 -0.71 -15.31 -0.81 2.37e-30 Prostate cancer; TGCT cis rs7224685 0.569 rs68060817 chr17:3995188 T/C cg09580393 chr17:4869866 SPAG7 -0.39 -4.49 -0.37 1.62e-5 Type 2 diabetes; TGCT cis rs9653442 0.545 rs11123813 chr2:100765692 C/T cg07810366 chr2:100720526 AFF3 -0.35 -5.24 -0.43 6.82e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs12220238 1.000 rs4745740 chr10:75942469 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs35883536 0.528 rs1855800 chr1:101030641 G/A cg10298815 chr1:101004474 GPR88 0.25 4.68 0.39 7.46e-6 Monocyte count; TGCT cis rs67311347 1.000 rs9865348 chr3:40397658 A/C cg13409248 chr3:40428643 ENTPD3 0.54 4.52 0.38 1.41e-5 Renal cell carcinoma; TGCT cis rs9368481 0.761 rs4358615 chr6:26998567 A/G cg18867708 chr6:26865862 GUSBL1 0.38 5.21 0.42 7.7300000000000005e-07 Autism spectrum disorder or schizophrenia; TGCT cis rs1552244 1.000 rs68045038 chr3:10151828 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs116095464 0.558 rs9312956 chr5:201812 T/C cg22857025 chr5:266934 NA -0.35 -6.52 -0.51 1.63e-9 Breast cancer; TGCT cis rs2404602 0.735 rs12906143 chr15:76709523 T/A cg22467129 chr15:76604101 ETFA 0.52 5.5 0.44 2.05e-7 Blood metabolite levels; TGCT cis rs854765 0.647 rs854809 chr17:18006539 C/T cg04398451 chr17:18023971 MYO15A -0.38 -6.48 -0.5 1.91e-9 Total body bone mineral density; TGCT cis rs7772486 0.875 rs7739371 chr6:146424353 C/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs909002 0.789 rs3817398 chr1:32119431 C/T cg11573219 chr1:32083031 HCRTR1 0.43 5.56 0.45 1.59e-7 Intelligence (multi-trait analysis); TGCT cis rs9372498 0.536 rs1319987 chr6:118782236 A/G cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs916888 0.610 rs199438 chr17:44791643 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.58 4.46 0.37 1.79e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17473412 1.000 rs10519723 chr5:122711641 T/C cg15125798 chr5:122621645 NA -0.6 -5.38 -0.43 3.61e-7 Total body bone mineral density; TGCT cis rs2580764 0.565 rs2919129 chr2:55216545 G/T cg09592903 chr2:55203963 RTN4 0.25 5.63 0.45 1.15e-7 Mean platelet volume; TGCT cis rs10892173 0.846 rs7943887 chr11:117670282 C/G cg07621104 chr11:117668040 DSCAML1 0.51 5.55 0.45 1.66e-7 Myopia; TGCT cis rs2243480 0.901 rs778693 chr7:65872345 T/G cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs868036 0.609 rs28742003 chr15:68127769 C/T cg05925327 chr15:68127851 NA -0.48 -4.6 -0.38 1.05e-5 Restless legs syndrome; TGCT cis rs4478858 0.684 rs4949373 chr1:31741577 G/A cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs9400467 0.506 rs73530915 chr6:111457448 A/G cg15721981 chr6:111408429 SLC16A10 0.71 4.59 0.38 1.05e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs36051895 0.625 rs12340344 chr9:5176281 C/A cg02405213 chr9:5042618 JAK2 -0.76 -10.62 -0.69 3.91e-19 Pediatric autoimmune diseases; TGCT cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs346785 0.692 rs7225131 chr17:74290097 T/A cg09812376 chr17:74270190 QRICH2 -0.36 -5.33 -0.43 4.43e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs12989701 0.935 rs12994284 chr2:127874020 T/C cg08168897 chr2:127865431 BIN1 0.5 5.34 0.43 4.28e-7 Alzheimer's disease (late onset); TGCT cis rs2046867 0.908 rs62251648 chr3:72806083 A/G cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7937682 0.575 rs7930208 chr11:111741463 T/C cg09085632 chr11:111637200 PPP2R1B 0.88 8.47 0.61 5.93e-14 Primary sclerosing cholangitis; TGCT cis rs2288278 0.601 rs2325948 chr17:46574491 C/T cg25032089 chr17:46643351 HOXB3 -0.4 -4.87 -0.4 3.36e-6 Hand grip strength; TGCT cis rs12681287 0.546 rs12546802 chr8:87499335 T/A cg27223183 chr8:87520930 FAM82B -0.92 -6.79 -0.52 4.12e-10 Caudate activity during reward; TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg04389838 chr3:44770851 ZNF501 -0.42 -5.67 -0.45 9.66e-8 Depressive symptoms; TGCT cis rs4862750 0.957 rs6858853 chr4:187903412 A/C cg22105103 chr4:187893119 NA -0.33 -4.78 -0.39 4.94e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs35146811 0.538 rs3823642 chr7:99796072 T/C cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs6121246 0.529 rs2889528 chr20:30210021 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs889312 0.500 rs832580 chr5:56172646 T/C cg12311346 chr5:56204834 C5orf35 -0.46 -5.0 -0.41 1.87e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs526231 0.819 rs2561476 chr5:102608834 T/C cg05225461 chr5:102596755 C5orf30 0.23 4.65 0.39 8.39e-6 Primary biliary cholangitis; TGCT cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.808 rs7559842 chr2:43673442 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.09 -0.42 1.3e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9457247 0.967 rs424185 chr6:167410907 C/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT trans rs7618501 0.501 rs7627864 chr3:49926613 C/G cg21659725 chr3:3221576 CRBN 0.68 7.77 0.57 2.53e-12 Intelligence (multi-trait analysis); TGCT cis rs4252435 0.520 rs76184304 chr7:142633490 C/G cg21621906 chr7:142494914 NA -1.09 -4.56 -0.38 1.22e-5 Cancer; TGCT cis rs7312933 0.703 rs10880259 chr12:42558003 T/C cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs8072100 0.967 rs4793842 chr17:45671506 G/A cg08085267 chr17:45401833 C17orf57 0.43 4.63 0.38 9.02e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs10992471 0.756 rs10115222 chr9:95128149 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.61 6.26 0.49 5.73e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6964587 1.000 rs6969536 chr7:91689351 C/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs1056107 0.866 rs12351043 chr9:115003292 G/A cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs9399137 0.507 rs7754722 chr6:135260303 T/C cg24558204 chr6:135376177 HBS1L -0.52 -5.24 -0.43 6.6e-7 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT trans rs28595532 0.702 rs55981733 chr4:119306600 G/A cg26518628 chr1:97050305 NA -0.61 -7.35 -0.55 2.35e-11 Cannabis dependence symptom count; TGCT cis rs7959452 0.557 rs7980883 chr12:69778914 C/T cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs9926296 0.656 rs7191144 chr16:89823393 C/T cg04287289 chr16:89883240 FANCA 0.63 6.24 0.49 6.2e-9 Vitiligo; TGCT cis rs6484504 0.553 rs2183484 chr11:31259370 G/A cg14844989 chr11:31128820 NA -0.25 -4.84 -0.4 3.76e-6 Red blood cell count; TGCT cis rs8077889 0.917 rs58080788 chr17:41902909 A/G cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs910316 0.967 rs12890371 chr14:75593839 T/C cg23033748 chr14:75592666 NEK9 0.28 4.79 0.39 4.73e-6 Height; TGCT cis rs8050907 0.744 rs55810554 chr16:4524392 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs11785400 0.793 rs4587307 chr8:143738529 G/A cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg12311346 chr5:56204834 C5orf35 0.85 7.78 0.57 2.42e-12 Initial pursuit acceleration; TGCT cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg13732083 chr21:47605072 C21orf56 -0.36 -4.68 -0.39 7.39e-6 Testicular germ cell tumor; TGCT cis rs67311347 0.955 rs11717036 chr3:40379578 G/T cg13683864 chr3:40499215 RPL14 1.0 10.45 0.68 1.05e-18 Renal cell carcinoma; TGCT cis rs2180341 1.000 rs6569480 chr6:127621748 A/G cg24812749 chr6:127587940 RNF146 0.87 7.21 0.54 4.85e-11 Breast cancer; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg01516881 chr6:292596 DUSP22 0.75 8.01 0.58 7.08e-13 Menopause (age at onset); TGCT cis rs6570726 0.764 rs4263604 chr6:145916697 A/G cg23711669 chr6:146136114 FBXO30 0.88 9.32 0.64 5.56e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9527 0.590 rs2148198 chr10:104915310 A/G cg04362960 chr10:104952993 NT5C2 -0.68 -5.81 -0.46 4.96e-8 Arsenic metabolism; TGCT cis rs7474896 0.583 rs11011346 chr10:38009483 C/T cg25427524 chr10:38739819 LOC399744 -0.32 -5.1 -0.42 1.23e-6 Obesity (extreme); TGCT cis rs1534166 1.000 rs1534166 chr3:133537067 C/T cg08048268 chr3:133502702 NA -0.41 -4.47 -0.37 1.73e-5 Alcohol consumption (transferrin glycosylation); TGCT cis rs6840360 0.571 rs11932059 chr4:152524496 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs1046896 0.520 rs9895409 chr17:80902719 C/T cg03160526 chr17:80928410 B3GNTL1 0.34 4.76 0.39 5.38e-6 Glycated hemoglobin levels; TGCT cis rs7267979 1.000 rs12428 chr20:25433821 G/T cg16686733 chr20:25566563 NINL -0.54 -5.49 -0.44 2.13e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11696501 0.739 rs6104252 chr20:44254323 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs10789491 1.000 rs12794 chr1:47141718 T/C cg15501359 chr1:47185051 KIAA0494 0.81 8.17 0.59 2.99e-13 Response to hepatitis C treatment; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg10150615 chr22:24372951 LOC391322 0.87 7.63 0.57 5.29e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9926296 0.632 rs4785716 chr16:89801127 T/C cg04287289 chr16:89883240 FANCA 0.67 6.64 0.51 8.68e-10 Vitiligo; TGCT cis rs7582180 0.629 rs12617779 chr2:100937707 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2997447 0.761 rs17184891 chr1:26447557 A/T cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs4319547 0.620 rs12372756 chr12:122815130 A/G cg08088222 chr12:122070432 ORAI1 0.26 4.69 0.39 7.14e-6 Body mass index; TGCT trans rs12339966 0.581 rs17788370 chr9:11338859 T/G cg03488587 chr11:64876988 C11orf2 0.32 7.04 0.53 1.16e-10 Systolic blood pressure; TGCT cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.63 6.65 0.51 8.58e-10 Height; TGCT cis rs7119038 0.580 rs7123726 chr11:118694547 T/C cg19308663 chr11:118741387 NA 0.27 5.67 0.45 9.63e-8 Sjögren's syndrome; TGCT cis rs4595586 0.545 rs7967931 chr12:39375162 A/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs6912958 0.781 rs6454632 chr6:88231824 A/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs7582180 0.638 rs9973536 chr2:100942243 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.92 -0.4 2.7e-6 Intelligence (multi-trait analysis); TGCT trans rs7615952 0.866 rs13063119 chr3:125643847 G/A cg07211511 chr3:129823064 LOC729375 -0.48 -8.0 -0.58 7.7e-13 Blood pressure (smoking interaction); TGCT cis rs910316 1.000 rs12589876 chr14:75544189 G/A cg11812906 chr14:75593930 NEK9 0.74 7.18 0.54 5.58e-11 Height; TGCT cis rs7804356 1.000 rs73065504 chr7:26825984 A/G cg03456212 chr7:26904342 SKAP2 -0.63 -4.84 -0.4 3.71e-6 Type 1 diabetes; TGCT cis rs826838 0.838 rs11183646 chr12:38799846 A/T cg26384229 chr12:38710491 ALG10B 1.06 10.68 0.69 2.84e-19 Heart rate; TGCT trans rs1496653 0.602 rs13092830 chr3:23363858 C/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs4843747 0.671 rs13334603 chr16:88116016 T/C cg06915872 chr16:87998081 BANP -0.3 -4.57 -0.38 1.14e-5 Menopause (age at onset); TGCT cis rs861020 0.606 rs657844 chr1:210006873 T/G cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs9341808 0.683 rs9359409 chr6:80826897 C/G cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs250677 0.958 rs36068 chr5:148417512 C/T cg23229984 chr5:148520753 ABLIM3 0.21 4.81 0.4 4.35e-6 Breast cancer; TGCT cis rs9653442 0.545 rs4851257 chr2:100775297 C/T cg22139774 chr2:100720529 AFF3 -0.36 -5.69 -0.46 8.67e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6674176 0.628 rs2301993 chr1:44426025 G/A cg12908607 chr1:44402522 ARTN -0.67 -8.15 -0.59 3.4e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg11890956 chr21:40555474 PSMG1 -0.72 -7.12 -0.54 7.51e-11 Menarche (age at onset); TGCT cis rs853679 0.517 rs9368550 chr6:28051803 T/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs739496 0.843 rs10774631 chr12:112023001 A/G cg10833066 chr12:111807467 FAM109A -0.39 -5.38 -0.43 3.6e-7 Platelet count; TGCT cis rs11677370 0.574 rs10190477 chr2:3862738 A/G cg17052675 chr2:3827356 NA 0.43 6.82 0.52 3.48e-10 Type 2 diabetes; TGCT cis rs7647973 0.710 rs1532204 chr3:49609477 C/G cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs7010267 0.570 rs6469794 chr8:120016099 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg24846343 chr22:24311635 DDTL 0.21 5.34 0.43 4.21e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2204008 0.627 rs10878488 chr12:38148666 G/A cg26384229 chr12:38710491 ALG10B 0.85 7.47 0.56 1.27e-11 Bladder cancer; TGCT cis rs1552244 0.572 rs3774208 chr3:10164722 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs7666738 0.830 rs11097606 chr4:99011486 C/T cg17366294 chr4:99064904 C4orf37 0.66 6.55 0.51 1.35e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4654899 0.758 rs6698462 chr1:21341293 G/C cg01072550 chr1:21505969 NA -0.55 -8.93 -0.63 4.73e-15 Superior frontal gyrus grey matter volume; TGCT cis rs13217239 0.646 rs10946888 chr6:26951678 A/G cg02458000 chr6:26745757 NA 0.49 4.53 0.38 1.38e-5 Schizophrenia; TGCT cis rs7584330 0.955 rs58643200 chr2:238389855 A/G cg08992911 chr2:238395768 MLPH 0.67 5.44 0.44 2.69e-7 Prostate cancer; TGCT cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg21724239 chr8:58056113 NA 0.44 4.72 0.39 6.3e-6 Developmental language disorder (linguistic errors); TGCT cis rs9457247 1.000 rs393727 chr6:167398632 T/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs2762353 0.574 rs4419666 chr6:25693274 C/T cg03517284 chr6:25882590 NA 0.9 8.79 0.62 1.04e-14 Blood metabolite levels; TGCT cis rs10501293 0.667 rs1844277 chr11:42982685 G/A cg03447554 chr11:43094025 NA 0.44 6.43 0.5 2.5e-9 Cognitive performance; TGCT cis rs35146811 0.625 rs2906645 chr7:99817859 A/G cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs78707713 0.560 rs55668536 chr10:71242655 A/G cg14388049 chr10:71211838 TSPAN15 -0.39 -4.64 -0.38 8.88e-6 Venous thromboembolism; TGCT cis rs10504229 0.683 rs7816733 chr8:58129855 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9388451 0.839 rs980014 chr6:126068001 T/G cg05901451 chr6:126070800 HEY2 -1.04 -15.8 -0.82 1.76e-31 Brugada syndrome; TGCT cis rs7917772 0.503 rs10883732 chr10:104293461 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9399135 0.967 rs9389254 chr6:135330709 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs523522 0.892 rs4767916 chr12:121024032 T/C cg12219531 chr12:120966889 COQ5 0.82 7.38 0.55 2.05e-11 High light scatter reticulocyte count; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg25151919 chr3:44754333 ZNF502 -0.46 -5.39 -0.44 3.47e-7 Depressive symptoms; TGCT cis rs7772486 0.790 rs6923545 chr6:146244743 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2797160 1.000 rs2747714 chr6:126007620 A/G cg05901451 chr6:126070800 HEY2 0.74 6.3 0.49 4.62e-9 Endometrial cancer; TGCT cis rs11098499 0.708 rs11732686 chr4:120252330 C/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs992157 0.835 rs12987180 chr2:219144089 G/A cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs11671005 0.735 rs34188294 chr19:58919557 G/A cg13877915 chr19:58951672 ZNF132 0.62 4.68 0.39 7.3e-6 Mean platelet volume; TGCT cis rs72945132 0.882 rs12289915 chr11:70131956 G/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7572733 0.534 rs7604700 chr2:198718630 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs2305707 0.867 rs16964228 chr15:51554955 C/T cg19946085 chr15:51559439 CYP19A1 0.49 5.2 0.42 8.08e-7 Height; TGCT cis rs933688 1.000 rs2052553 chr5:90729906 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 9.6 0.65 1.2e-16 Smoking behavior; TGCT cis rs13118159 0.742 rs34947293 chr4:1335034 T/C cg13395646 chr4:1353034 KIAA1530 -0.41 -4.72 -0.39 6.24e-6 Longevity; TGCT cis rs6088580 0.634 rs6059851 chr20:33047945 G/A cg08999081 chr20:33150536 PIGU 0.29 5.6 0.45 1.31e-7 Glomerular filtration rate (creatinine); TGCT cis rs2688608 0.967 rs2688609 chr10:75658181 A/G cg04320760 chr10:75533139 FUT11 0.29 4.44 0.37 2e-5 Inflammatory bowel disease; TGCT cis rs7582180 0.739 rs11123822 chr2:100911582 G/T cg08017756 chr2:100939284 LONRF2 -0.28 -4.82 -0.4 4.18e-6 Intelligence (multi-trait analysis); TGCT trans rs2727020 0.729 rs7924782 chr11:49267249 A/G cg15704280 chr7:45808275 SEPT13 -0.78 -9.13 -0.63 1.58e-15 Coronary artery disease; TGCT cis rs79349575 0.783 rs62078372 chr17:47028989 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs12142240 0.698 rs56909107 chr1:46808224 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs4689388 0.581 rs1801212 chr4:6302519 C/T cg25554036 chr4:6271136 WFS1 0.53 6.36 0.5 3.56e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs67311347 0.955 rs6773383 chr3:40377412 A/T cg13683864 chr3:40499215 RPL14 -0.96 -9.72 -0.66 6.04e-17 Renal cell carcinoma; TGCT cis rs7607369 0.648 rs7559490 chr2:219656867 A/T cg02176678 chr2:219576539 TTLL4 -0.47 -6.0 -0.47 1.98e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs854765 0.663 rs2236513 chr17:17747366 A/C cg04398451 chr17:18023971 MYO15A 0.31 4.65 0.39 8.49e-6 Total body bone mineral density; TGCT cis rs66561647 0.634 rs10097497 chr8:128932363 A/G cg11792826 chr8:129160931 MIR1208 0.21 4.83 0.4 3.95e-6 Hemoglobin concentration; TGCT cis rs7223966 0.960 rs7212379 chr17:61706122 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.84 0.4 3.71e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3749237 0.595 rs17595772 chr3:49409704 G/A cg02487422 chr3:49467188 NICN1 0.59 6.01 0.47 1.92e-8 Resting heart rate; TGCT trans rs6089829 0.962 rs6011544 chr20:61658782 T/C cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs28595532 0.920 rs116697254 chr4:119733603 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs2692947 0.732 rs56847058 chr2:96406893 C/T cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg23649088 chr2:200775458 C2orf69 0.47 9.82 0.66 3.39e-17 Osteoporosis; TGCT cis rs8068544 0.818 rs78333491 chr17:40163138 A/G cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.07 -5.1 -0.42 1.26e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs2797160 1.000 rs1777225 chr6:126018270 T/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs57221529 0.825 rs72703051 chr5:582997 G/A cg16624210 chr5:671434 TPPP 0.42 4.48 0.37 1.67e-5 Lung disease severity in cystic fibrosis; TGCT cis rs7617773 0.746 rs4371540 chr3:48353543 G/A cg11946769 chr3:48343235 NME6 0.82 7.08 0.54 9.51e-11 Coronary artery disease; TGCT cis rs523522 0.962 rs9040 chr12:120900274 C/T cg27279351 chr12:120934652 DYNLL1 0.74 6.44 0.5 2.42e-9 High light scatter reticulocyte count; TGCT cis rs9309473 0.583 rs35885918 chr2:73612234 T/C cg20560298 chr2:73613845 ALMS1 -0.48 -5.37 -0.43 3.68e-7 Metabolite levels; TGCT cis rs210138 1.000 rs210144 chr6:33547430 G/A cg07679836 chr6:33548423 BAK1 0.4 5.57 0.45 1.52e-7 Testicular germ cell tumor; TGCT cis rs3733585 0.624 rs58130873 chr4:9972081 T/C cg00071950 chr4:10020882 SLC2A9 -0.57 -6.83 -0.52 3.41e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg01802117 chr1:53393560 SCP2 -0.44 -5.52 -0.44 1.86e-7 Monocyte count; TGCT cis rs6725041 0.532 rs12623803 chr2:213201642 G/C cg16329650 chr2:213403929 ERBB4 -0.67 -5.86 -0.47 3.89e-8 QT interval (ambient particulate matter interaction); TGCT cis rs9905704 0.647 rs9898048 chr17:57108543 C/T cg12560992 chr17:57184187 TRIM37 0.62 5.52 0.44 1.9e-7 Testicular germ cell tumor; TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg08736216 chr1:53307985 ZYG11A -0.24 -4.74 -0.39 5.75e-6 Monocyte count; TGCT cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg23205692 chr1:25664452 TMEM50A 0.5 5.19 0.42 8.24e-7 Erythrocyte sedimentation rate; TGCT cis rs8072100 0.576 rs12948299 chr17:45403057 T/C cg08085267 chr17:45401833 C17orf57 -0.67 -7.26 -0.55 3.74e-11 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1005277 0.579 rs2474574 chr10:38387295 C/T cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs1059312 1.000 rs7970815 chr12:129288366 G/A cg09035930 chr12:129282057 SLC15A4 0.58 11.32 0.71 7.78e-21 Systemic lupus erythematosus; TGCT cis rs4654899 1.000 rs10799686 chr1:21486445 A/T cg01072550 chr1:21505969 NA 0.51 8.26 0.6 1.91e-13 Superior frontal gyrus grey matter volume; TGCT cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT cis rs1059312 1.000 rs7135854 chr12:129279988 G/C cg09035930 chr12:129282057 SLC15A4 0.6 12.05 0.73 1.31e-22 Systemic lupus erythematosus; TGCT cis rs17102423 0.760 rs2781375 chr14:65569597 A/G cg11161011 chr14:65562177 MAX -0.43 -5.85 -0.46 4.19e-8 Obesity-related traits; TGCT cis rs2300747 0.872 rs10754445 chr1:117077459 A/T cg26677431 chr1:117075710 CD58 -0.23 -4.56 -0.38 1.23e-5 Primary biliary cholangitis;Multiple sclerosis; TGCT trans rs1814175 0.645 rs2140602 chr11:50022800 G/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs1552244 0.882 rs13063929 chr3:10010308 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.81 0.46 4.88e-8 Alzheimer's disease; TGCT cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg23205692 chr1:25664452 TMEM50A 0.48 5.07 0.41 1.42e-6 Plateletcrit;Mean corpuscular volume; TGCT cis rs3784262 0.565 rs12914603 chr15:58350896 C/G cg12031962 chr15:58353849 ALDH1A2 -0.38 -5.57 -0.45 1.53e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9660992 0.573 rs12140422 chr1:205187981 G/A cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs9393777 0.778 rs13219354 chr6:27185664 T/C cg10876282 chr6:28092338 ZSCAN16 0.71 4.62 0.38 9.6e-6 Intelligence (multi-trait analysis); TGCT cis rs2455799 0.517 rs1345158 chr3:15931704 G/T cg12172478 chr3:16357591 RFTN1 -0.32 -4.66 -0.39 8.01e-6 Mean platelet volume; TGCT cis rs7542091 0.635 rs7550733 chr1:210044968 G/A cg23283495 chr1:209979779 IRF6 0.55 5.5 0.44 2.12e-7 Monobrow; TGCT cis rs7044106 0.762 rs10760112 chr9:123467570 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.59 6.16 0.48 9.29e-9 Hip circumference adjusted for BMI; TGCT cis rs9291683 0.507 rs6845554 chr4:10013173 T/G cg00071950 chr4:10020882 SLC2A9 0.66 7.82 0.57 1.96e-12 Bone mineral density; TGCT cis rs9859260 0.555 rs9877493 chr3:195832147 T/C cg02975922 chr3:195473998 MUC4 -0.24 -4.68 -0.39 7.34e-6 Mean corpuscular volume; TGCT cis rs2295359 0.637 rs12044149 chr1:67600686 G/T cg03340356 chr1:67600835 NA 0.46 5.4 0.44 3.21e-7 Psoriasis; TGCT cis rs9300255 0.596 rs10734901 chr12:123743447 G/A cg00376283 chr12:123451042 ABCB9 0.79 6.68 0.51 7.08e-10 Neutrophil percentage of white cells; TGCT cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs4953076 0.573 rs6726680 chr2:44406686 C/G cg04920474 chr2:44395004 PPM1B 0.59 5.65 0.45 1.02e-7 Height; TGCT cis rs10744422 1.000 rs936083 chr12:123338964 A/G cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs6669919 0.933 rs10863899 chr1:211666218 A/G cg26515805 chr1:211431828 RCOR3 -0.41 -4.72 -0.39 6.34e-6 Intelligence (multi-trait analysis); TGCT cis rs6665290 0.935 rs12409755 chr1:227196949 A/T cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs17376456 0.825 rs17374166 chr5:93238655 T/C cg21475434 chr5:93447410 FAM172A 0.7 4.9 0.4 2.96e-6 Diabetic retinopathy; TGCT cis rs696279 1.000 rs696279 chr7:16700798 A/G cg08595592 chr7:16780162 NA -0.24 -4.7 -0.39 6.86e-6 Mean platelet volume; TGCT cis rs2239547 0.522 rs9842974 chr3:53011050 C/A cg11645453 chr3:52864694 ITIH4 0.34 5.51 0.44 2.02e-7 Schizophrenia; TGCT cis rs80282103 0.867 rs74117668 chr10:1076620 C/T cg08668510 chr10:1095578 IDI1 1.18 5.51 0.44 2.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs2228479 0.702 rs62056100 chr16:89939753 C/T cg06558623 chr16:89946397 TCF25 0.62 6.98 0.53 1.61e-10 Skin colour saturation; TGCT cis rs1784581 0.588 rs10945792 chr6:162423484 C/T cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs6546537 0.955 rs7590422 chr2:69883715 T/C cg10773587 chr2:69614142 GFPT1 -0.68 -5.99 -0.47 2.13e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs1205863 1.000 rs1205873 chr6:11945345 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs6547741 1.000 rs10165098 chr2:27796526 C/T cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs9921222 0.565 rs10903014 chr16:377623 A/G cg10349874 chr16:420996 TMEM8A;MRPL28 -0.28 -5.01 -0.41 1.84e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs17401966 0.931 rs12130563 chr1:10428452 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs778371 0.874 rs1083522 chr2:233745521 C/T cg08000102 chr2:233561755 GIGYF2 -0.6 -6.42 -0.5 2.62e-9 Schizophrenia; TGCT cis rs752092 1.000 rs11636578 chr15:101787969 T/C cg25114630 chr15:101792522 CHSY1 0.56 5.42 0.44 2.95e-7 Corneal structure; TGCT cis rs3771570 1.000 rs56222556 chr2:242364119 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.97e-10 Prostate cancer; TGCT cis rs35306767 0.761 rs12773961 chr10:1013215 C/G cg26597838 chr10:835615 NA 0.58 6.43 0.5 2.46e-9 Eosinophil percentage of granulocytes; TGCT cis rs7542091 0.704 rs1883331 chr1:210043483 A/G cg00989853 chr1:209979345 IRF6 0.43 4.58 0.38 1.12e-5 Monobrow; TGCT cis rs7095607 0.560 rs2255381 chr10:69923535 C/T cg18986048 chr10:69913749 MYPN 0.53 5.54 0.45 1.7e-7 Lung function (FVC); TGCT cis rs17601876 0.814 rs8039089 chr15:51561328 T/G cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs6964587 1.000 rs6465347 chr7:91693837 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs9787249 0.957 rs10888958 chr1:40211737 T/C cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs1018836 0.892 rs4735210 chr8:91549399 G/T cg16814680 chr8:91681699 NA -0.78 -8.29 -0.6 1.62e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1729951 0.546 rs361246 chr3:136695667 G/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.62e-9 Neuroticism; TGCT cis rs9611519 1.000 rs4820433 chr22:41607065 C/G cg03806693 chr22:41940476 POLR3H -0.66 -6.3 -0.49 4.65e-9 Neuroticism; TGCT cis rs7216064 0.953 rs12450907 chr17:65870644 T/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7091068 0.518 rs1543580 chr10:95446811 C/T cg20715218 chr10:95462985 C10orf4 0.52 5.46 0.44 2.46e-7 Urinary tract infection frequency; TGCT cis rs6964587 0.967 rs410 chr7:91557425 C/G cg17063962 chr7:91808500 NA -0.88 -9.29 -0.64 6.5e-16 Breast cancer; TGCT cis rs79349575 0.783 rs12453374 chr17:46994846 G/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs1552244 0.572 rs41464050 chr3:10158393 A/G cg00149659 chr3:10157352 C3orf10 1.11 7.56 0.56 7.81e-12 Alzheimer's disease; TGCT cis rs6964587 0.967 rs10953065 chr7:91808915 A/G cg17063962 chr7:91808500 NA -0.92 -9.84 -0.66 3.11e-17 Breast cancer; TGCT cis rs55823223 0.648 rs936394 chr17:73852008 C/A cg23806715 chr17:73775811 H3F3B 0.55 4.55 0.38 1.26e-5 Psoriasis; TGCT cis rs13326165 0.760 rs9861879 chr3:52424001 A/G cg07884673 chr3:53033167 SFMBT1 0.4 4.86 0.4 3.45e-6 HDL cholesterol;HDL cholesterol levels; TGCT trans rs629535 0.748 rs689410 chr8:70037558 G/A cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg23708337 chr7:1209742 NA 0.54 4.79 0.4 4.62e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11098499 0.874 rs7661020 chr4:120106982 T/C cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs6912958 0.559 rs1201409 chr6:88055264 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.82 0.46 4.73e-8 Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs72882693 chr4:98960804 T/A cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs240768 0.511 rs61289570 chr6:101403098 C/T cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs17253792 0.822 rs79291233 chr14:56065302 G/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs13217239 0.646 rs7451149 chr6:27057518 A/G cg02458000 chr6:26745757 NA -0.53 -4.88 -0.4 3.17e-6 Schizophrenia; TGCT cis rs928736 0.599 rs1000005 chr21:34433051 C/G cg10915739 chr21:34405733 NA 0.41 5.13 0.42 1.09e-6 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7539409 0.831 rs10874417 chr1:84220731 C/T cg10977910 chr1:84465055 TTLL7 -0.79 -4.81 -0.4 4.32e-6 Alzheimer's disease; TGCT trans rs1499614 1.000 rs2659911 chr7:66158420 G/A cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs889312 0.500 rs252903 chr5:56117952 A/G cg12311346 chr5:56204834 C5orf35 -0.49 -5.44 -0.44 2.77e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs6815814 0.898 rs1873195 chr4:38891173 C/T cg02016764 chr4:38805732 TLR1 -0.34 -5.02 -0.41 1.79e-6 Breast cancer; TGCT trans rs208520 0.754 rs851594 chr6:66876695 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.31 -0.68 2.29e-18 Exhaled nitric oxide output; TGCT cis rs10464366 0.746 rs34792397 chr7:39146331 G/A cg18850127 chr7:39170497 POU6F2 0.28 5.93 0.47 2.76e-8 IgG glycosylation; TGCT cis rs6964587 1.000 rs11981461 chr7:91692662 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs9549260 0.755 rs4429172 chr13:41189143 C/A cg21288729 chr13:41239152 FOXO1 1.02 10.32 0.68 2.17e-18 Red blood cell count; TGCT cis rs4319547 0.915 rs3803005 chr12:123110654 T/C cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.47 -0.44 2.39e-7 Body mass index; TGCT cis rs2980439 0.525 rs1850511 chr8:8170329 T/A cg08975724 chr8:8085496 FLJ10661 0.55 4.69 0.39 7.06e-6 Neuroticism; TGCT cis rs344364 0.511 rs2982446 chr16:1947153 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9682041 1.000 rs4955588 chr3:170072864 C/A cg07589077 chr3:170072950 NA 0.32 5.24 0.43 6.78e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs2153535 0.580 rs2327064 chr6:8454052 C/T cg07606381 chr6:8435919 SLC35B3 0.52 4.9 0.4 2.92e-6 Motion sickness; TGCT cis rs6714710 0.603 rs35424768 chr2:98395653 A/C cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs1881797 0.872 rs12408686 chr1:247691141 C/T cg14830002 chr1:247616686 OR2B11 0.39 4.46 0.37 1.81e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs10883723 0.579 rs1967815 chr10:104287051 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.7 6.15 0.48 9.9e-9 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6121246 0.567 rs7361893 chr20:30200751 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.68 0.39 7.29e-6 Mean corpuscular hemoglobin; TGCT cis rs3785574 0.962 rs8079161 chr17:61808561 C/G cg01411255 chr17:61851458 DDX42;CCDC47 1.11 14.36 0.79 3.89e-28 Height; TGCT cis rs6570726 1.000 rs373778 chr6:145873252 C/T cg05347473 chr6:146136440 FBXO30 0.5 4.46 0.37 1.82e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 1.000 rs7588802 chr2:26277789 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 1.99e-6 Gut microbiome composition (summer); TGCT cis rs763014 0.966 rs7185390 chr16:666382 A/G cg09263875 chr16:632152 PIGQ 0.31 6.88 0.53 2.65e-10 Height; TGCT cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Mean corpuscular hemoglobin; TGCT cis rs28735056 0.904 rs12953738 chr18:77627877 A/G cg20368463 chr18:77673604 PQLC1 0.4 4.89 0.4 3.09e-6 Schizophrenia; TGCT cis rs7264396 0.524 rs3790136 chr20:34143278 A/T cg23834711 chr20:33872785 EIF6 0.75 4.59 0.38 1.05e-5 Total cholesterol levels; TGCT cis rs7772486 0.875 rs854146 chr6:146341033 A/G cg13319975 chr6:146136371 FBXO30 -0.53 -4.8 -0.4 4.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4727027 0.933 rs13225884 chr7:148857795 A/G cg23583168 chr7:148888333 NA -0.69 -8.86 -0.62 6.94e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4665809 1.000 rs6546728 chr2:26276531 G/C cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT trans rs77457752 0.690 rs12335400 chr9:13912195 A/G cg23609682 chr1:3070786 PRDM16 0.51 7.14 0.54 6.89e-11 Breast cancer; TGCT cis rs858239 0.601 rs6461702 chr7:23249273 C/G cg05602783 chr7:23145260 KLHL7 -0.72 -5.65 -0.45 1.04e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg15687855 chr3:44754131 ZNF502 -0.52 -6.31 -0.49 4.58e-9 Depressive symptoms; TGCT cis rs16958440 0.867 rs77348110 chr18:44674167 T/C cg17192377 chr18:44677553 HDHD2 0.61 4.85 0.4 3.65e-6 Sitting height ratio; TGCT cis rs7267979 1.000 rs6115140 chr20:25285507 C/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8050907 0.744 rs17137053 chr16:4524155 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs9527 0.615 rs7080462 chr10:104736699 T/C cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg05985448 chr10:134359359 INPP5A 0.23 5.03 0.41 1.68e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7917772 0.503 rs11191326 chr10:104302959 C/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4499344 0.622 rs10401677 chr19:33061120 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 4.97 0.41 2.2e-6 Mean platelet volume; TGCT cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg05738196 chr6:26577821 NA 0.87 10.31 0.68 2.25e-18 Intelligence (multi-trait analysis); TGCT cis rs3806933 0.522 rs12515367 chr5:110447853 A/G cg04022379 chr5:110408740 TSLP 0.6 6.25 0.49 6.08e-9 Eosinophilic esophagitis; TGCT cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs17401966 0.838 rs4475756 chr1:10387788 A/G cg19773385 chr1:10388646 KIF1B -0.23 -5.53 -0.44 1.79e-7 Hepatocellular carcinoma; TGCT cis rs6121246 0.529 rs6060118 chr20:30171209 T/C cg13852791 chr20:30311386 BCL2L1 0.72 4.96 0.41 2.27e-6 Mean corpuscular hemoglobin; TGCT trans rs2288327 0.557 rs7588593 chr2:179352450 T/C cg18634211 chr1:26737262 LIN28 0.91 6.86 0.52 2.86e-10 Atrial fibrillation; TGCT cis rs6759518 0.655 rs4665374 chr2:27413096 A/G cg26210250 chr2:26863503 CIB4 -0.81 -4.48 -0.37 1.66e-5 Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs734999 0.545 rs10797441 chr1:2551660 T/G cg18854424 chr1:2615690 NA 0.45 5.15 0.42 1e-6 Ulcerative colitis; TGCT cis rs10504229 0.683 rs11786843 chr8:58133629 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6674176 0.660 rs6680421 chr1:44408969 A/C cg12908607 chr1:44402522 ARTN 0.72 9.1 0.63 1.86e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2806561 0.765 rs1997866 chr1:23512524 A/G cg12483005 chr1:23474871 LUZP1 0.38 4.74 0.39 5.77e-6 Height; TGCT cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg11301795 chr4:187892539 NA 0.3 4.55 0.38 1.24e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs727505 1.000 rs2286175 chr7:124431032 G/A cg23710748 chr7:124431027 NA -0.26 -4.57 -0.38 1.16e-5 Lewy body disease; TGCT cis rs1552244 0.608 rs7615408 chr3:10000186 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.62 4.57 0.38 1.15e-5 Alzheimer's disease; TGCT cis rs875971 0.964 rs6978429 chr7:65959876 T/G cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs2288278 0.601 rs11079826 chr17:46597048 C/T cg25032089 chr17:46643351 HOXB3 -0.43 -5.07 -0.41 1.43e-6 Hand grip strength; TGCT cis rs7572733 0.534 rs1401095 chr2:198779867 C/T cg00792783 chr2:198669748 PLCL1 -0.56 -5.11 -0.42 1.21e-6 Dermatomyositis; TGCT cis rs1552244 0.882 rs9812006 chr3:10022658 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.85 5.46 0.44 2.47e-7 Alzheimer's disease; TGCT cis rs2072499 0.750 rs55910626 chr1:156159909 C/G cg25208724 chr1:156163844 SLC25A44 1.01 9.25 0.64 8.38e-16 Testicular germ cell tumor; TGCT cis rs4699052 0.590 rs1356293 chr4:104288200 A/C cg16532752 chr4:104119610 CENPE -0.5 -4.75 -0.39 5.48e-6 Testicular germ cell tumor; TGCT cis rs2439831 0.618 rs8023508 chr15:44176103 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.73 -5.46 -0.44 2.47e-7 Lung cancer in ever smokers; TGCT cis rs12643440 0.538 rs62296685 chr4:17137580 T/C cg22650099 chr4:17144496 NA -0.45 -4.61 -0.38 9.97e-6 Metabolite levels (Pyroglutamine); TGCT cis rs9467711 0.606 rs9348712 chr6:26366511 T/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9300255 0.739 rs2337934 chr12:123745359 A/G cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs12681287 0.640 rs4587306 chr8:87385511 T/C cg27223183 chr8:87520930 FAM82B 0.89 6.61 0.51 1.04e-9 Caudate activity during reward; TGCT cis rs6582630 0.519 rs12582285 chr12:38298753 C/T cg13010199 chr12:38710504 ALG10B 0.57 4.45 0.37 1.89e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs6504340 0.793 rs56128659 chr17:46621828 T/A cg25032089 chr17:46643351 HOXB3 0.56 5.23 0.43 6.86e-7 Primary tooth development (number of teeth); TGCT cis rs2299587 0.554 rs2073562 chr8:17742929 A/G cg01800426 chr8:17659068 MTUS1 -0.55 -4.96 -0.41 2.25e-6 Economic and political preferences; TGCT cis rs858239 0.600 rs7799422 chr7:23128413 G/A cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2760061 0.583 rs3094911 chr1:228210179 A/G cg18477163 chr1:228402036 OBSCN 0.35 7.23 0.54 4.44e-11 Diastolic blood pressure; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.39 5.19 0.42 8.48e-7 Lymphocyte counts; TGCT cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg09359103 chr1:154839909 KCNN3 -0.64 -12.0 -0.73 1.72e-22 Prostate cancer; TGCT cis rs7666738 0.927 rs11736876 chr4:98987206 A/G cg18180107 chr4:99064573 C4orf37 0.56 4.54 0.38 1.3e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9372498 0.536 rs55899435 chr6:118812099 C/T cg21191810 chr6:118973309 C6orf204 -0.35 -4.72 -0.39 6.2e-6 Diastolic blood pressure; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg15242686 chr22:24348715 GSTTP1 0.47 6.61 0.51 1.04e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2562456 0.876 rs11668606 chr19:21737420 T/G cg25650185 chr19:21324782 ZNF431 -0.64 -5.73 -0.46 7.12e-8 Pain; TGCT cis rs7666738 0.830 rs11097608 chr4:99011693 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.83 0.46 4.6e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs4332037 0.552 rs11773627 chr7:2002733 A/G cg25206134 chr2:45395956 NA 0.89 7.1 0.54 8.38e-11 Bipolar disorder; TGCT cis rs1215050 0.904 rs1727285 chr4:98978821 G/A cg05340658 chr4:99064831 C4orf37 -0.46 -5.55 -0.45 1.67e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs12655019 0.920 rs1466010 chr5:56213156 A/G cg25190722 chr1:3801660 DFFB 0.63 7.15 0.54 6.66e-11 Breast cancer (early onset); TGCT cis rs11585357 0.895 rs2977305 chr1:17613737 A/T cg08277548 chr1:17600880 PADI3 0.96 9.72 0.66 5.97e-17 Hair shape; TGCT cis rs2120019 0.935 rs34913788 chr15:75372617 A/C cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs4253772 0.637 rs8139035 chr22:46651367 A/G cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs6598955 0.950 rs6700455 chr1:26545864 T/C cg04990556 chr1:26633338 UBXN11 0.87 10.34 0.68 1.87e-18 Obesity-related traits; TGCT cis rs6938 0.618 rs1133323 chr15:75212225 C/T cg10253484 chr15:75165896 SCAMP2 -0.57 -5.23 -0.43 6.92e-7 Breast cancer; TGCT cis rs782590 0.967 rs782588 chr2:55841640 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.88 0.53 2.6e-10 Metabolic syndrome; TGCT cis rs9486719 1.000 rs9486719 chr6:97060124 G/A cg18709589 chr6:96969512 KIAA0776 -0.79 -6.08 -0.48 1.4e-8 Migraine;Coronary artery disease; TGCT cis rs1005277 0.579 rs1621040 chr10:38497232 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.22 -0.59 2.35e-13 Extrinsic epigenetic age acceleration; TGCT cis rs35306767 0.903 rs11815185 chr10:923617 T/A cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs8064299 0.597 rs2053748 chr17:72775911 A/G cg25054828 chr17:72772726 NAT9;TMEM104 -0.91 -10.03 -0.67 1.04e-17 Monocyte count; TGCT cis rs6688613 0.679 rs12116418 chr1:166944273 T/A cg07049167 chr1:166818506 POGK 0.22 4.53 0.38 1.39e-5 Refractive astigmatism; TGCT cis rs1801251 1.000 rs56777991 chr2:233635388 A/C cg25237894 chr2:233734115 C2orf82 0.31 5.62 0.45 1.21e-7 Coronary artery disease; TGCT cis rs6570726 0.791 rs9376953 chr6:145912226 G/T cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3935685 0.874 rs12911718 chr15:78004325 G/A cg25212270 chr15:78015279 NA 0.26 5.63 0.45 1.12e-7 Intelligence (multi-trait analysis); TGCT cis rs2115630 1.000 rs58581703 chr15:85276935 C/T cg11189052 chr15:85197271 WDR73 -0.62 -6.0 -0.47 2e-8 P wave terminal force; TGCT cis rs4900538 0.855 rs1210074 chr14:102889098 G/A cg18135206 chr14:102964638 TECPR2 -0.2 -4.53 -0.38 1.39e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2242116 0.734 rs4683294 chr3:46979013 C/G cg02527881 chr3:46936655 PTH1R 0.3 5.65 0.45 1.02e-7 Birth weight; TGCT cis rs6754311 0.597 rs2082729 chr2:136550109 C/T cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Mosquito bite size; TGCT cis rs910316 0.967 rs4899549 chr14:75647494 G/A cg11812906 chr14:75593930 NEK9 -0.72 -7.1 -0.54 8.47e-11 Height; TGCT cis rs61931739 0.517 rs7313663 chr12:34417058 T/C cg06521331 chr12:34319734 NA -0.29 -4.59 -0.38 1.06e-5 Morning vs. evening chronotype; TGCT cis rs7666738 0.830 rs17027090 chr4:98897923 G/T cg18180107 chr4:99064573 C4orf37 0.53 4.81 0.4 4.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.654 rs619727 chr11:68627535 A/G cg06112835 chr11:68658793 MRPL21 0.47 8.07 0.59 5.3e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg03264133 chr6:25882463 NA -0.78 -8.14 -0.59 3.58e-13 Blood metabolite levels; TGCT cis rs1538970 0.781 rs12049503 chr1:46021556 G/T cg05343316 chr1:45956843 TESK2 0.67 5.2 0.42 7.96e-7 Platelet count; TGCT cis rs7727544 0.582 rs2278398 chr5:131530441 C/T cg14196790 chr5:131705035 SLC22A5 -0.33 -4.45 -0.37 1.89e-5 Blood metabolite levels; TGCT cis rs9926296 0.609 rs4785709 chr16:89796665 G/A cg03388025 chr16:89894329 SPIRE2 -0.33 -4.79 -0.4 4.58e-6 Vitiligo; TGCT cis rs7666738 0.830 rs1534319 chr4:98964804 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11650494 0.908 rs73340399 chr17:47372743 G/C cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs11679640 0.610 rs4494803 chr2:43109042 G/T cg00484711 chr2:42331922 NA -0.2 -4.53 -0.38 1.39e-5 White matter hyperintensity burden; TGCT cis rs7618915 0.547 rs11714419 chr3:52628816 A/G cg07507251 chr3:52567010 NT5DC2 0.46 6.62 0.51 9.64e-10 Bipolar disorder; TGCT cis rs9291683 0.620 rs11722946 chr4:10125990 A/G cg00071950 chr4:10020882 SLC2A9 -0.43 -4.73 -0.39 6.01e-6 Bone mineral density; TGCT cis rs1218582 0.661 rs4845695 chr1:154911798 A/G cg24250549 chr1:154909240 PMVK 0.47 4.49 0.37 1.58e-5 Prostate cancer; TGCT cis rs6918586 0.658 rs198856 chr6:26102708 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.09e-9 Schizophrenia; TGCT cis rs896854 0.936 rs10108430 chr8:95961794 C/T cg13393036 chr8:95962371 TP53INP1 -0.63 -8.72 -0.62 1.53e-14 Type 2 diabetes; TGCT cis rs826838 1.000 rs2129627 chr12:38653036 C/T cg13010199 chr12:38710504 ALG10B 0.77 6.31 0.49 4.59e-9 Heart rate; TGCT cis rs727505 1.000 rs7806680 chr7:124433079 G/A cg23710748 chr7:124431027 NA -0.26 -4.6 -0.38 1.03e-5 Lewy body disease; TGCT trans rs10504390 0.656 rs79616747 chr8:66546593 C/A cg18118147 chr19:51128640 SYT3 -0.77 -6.85 -0.52 2.99e-10 IgG glycosylation; TGCT trans rs12599106 0.792 rs76039834 chr16:34598453 G/A cg07332563 chr6:291687 DUSP22 -0.66 -6.76 -0.52 4.86e-10 Menopause (age at onset); TGCT cis rs854765 0.603 rs4506967 chr17:17990474 A/C cg04398451 chr17:18023971 MYO15A -0.37 -6.51 -0.5 1.71e-9 Total body bone mineral density; TGCT cis rs986417 0.688 rs965454 chr14:60960251 T/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT trans rs28595532 0.557 rs13435618 chr4:119308814 C/T cg26518628 chr1:97050305 NA -0.52 -7.8 -0.57 2.17e-12 Cannabis dependence symptom count; TGCT cis rs7822232 0.908 rs7821112 chr8:145147169 G/A cg06239191 chr8:145163136 KIAA1875 0.88 6.45 0.5 2.26e-9 Blood metabolite levels; TGCT cis rs68170813 0.559 rs80017637 chr7:107050660 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs8038465 0.615 rs4075802 chr15:73963239 A/G cg15420318 chr15:73925796 NPTN 0.74 8.25 0.6 1.95e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4563143 0.663 rs2218396 chr19:29236392 C/T cg03161606 chr19:29218774 NA 0.54 5.79 0.46 5.31e-8 Methadone dose in opioid dependence; TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.9 -0.4 2.97e-6 Prudent dietary pattern; TGCT cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg07636037 chr3:49044803 WDR6 0.84 8.59 0.61 3.04e-14 Menarche (age at onset); TGCT cis rs17767294 0.708 rs62620226 chr6:28121278 A/G cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs8177253 1.000 rs6762719 chr3:133480817 A/G cg16414030 chr3:133502952 NA -0.61 -9.65 -0.66 8.74e-17 Iron status biomarkers; TGCT cis rs7523050 0.730 rs72984612 chr1:109434826 T/C cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT trans rs1033284 0.666 rs11694579 chr2:141928874 T/G cg17884674 chr19:1967198 CSNK1G2 -0.32 -6.65 -0.51 8.5e-10 Blood pressure (smoking interaction); TGCT cis rs9388451 0.869 rs7764016 chr6:126070789 T/G cg10911889 chr6:126070802 HEY2 0.56 5.82 0.46 4.69e-8 Brugada syndrome; TGCT cis rs2692947 0.770 rs11689832 chr2:96554851 A/C cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6032067 0.543 rs13045693 chr20:43911817 T/C cg16667508 chr20:43936853 MATN4;RBPJL -0.38 -6.0 -0.47 2.04e-8 Blood protein levels; TGCT cis rs644799 1.000 rs564675 chr11:95561873 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3020333 0.875 rs2941742 chr6:152012988 A/G cg22157087 chr6:152012887 ESR1 0.19 4.65 0.39 8.27e-6 Total body bone mineral density; TGCT cis rs68170813 0.559 rs113211438 chr7:106969198 G/A cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs6964587 1.000 rs1859113 chr7:91679887 T/C cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs6504950 0.720 rs9913784 chr17:52989071 A/T cg07707039 chr17:53042137 COX11 0.27 4.63 0.38 8.98e-6 Breast cancer; TGCT cis rs2677744 0.719 rs12902422 chr15:91469846 T/C cg23684204 chr15:91497937 RCCD1 0.33 4.71 0.39 6.4e-6 Attention deficit hyperactivity disorder; TGCT trans rs2840044 0.554 rs225267 chr17:33964228 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Response to radiotherapy in cancer (late toxicity); TGCT cis rs13177918 0.603 rs10447222 chr5:149832667 A/G cg14059543 chr5:149831962 NA -0.68 -9.02 -0.63 2.93e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs806215 1.000 rs2106187 chr7:127241353 C/T cg25922125 chr7:127225783 GCC1 0.59 5.98 0.47 2.17e-8 Type 2 diabetes; TGCT cis rs12950390 0.853 rs11655112 chr17:45856563 T/C cg06532163 chr17:45867833 NA 0.37 5.89 0.47 3.46e-8 IgG glycosylation; TGCT cis rs13064411 0.696 rs36054418 chr3:113204762 G/T cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs12367572 0.930 rs11615964 chr12:45261564 C/T cg04608330 chr12:45269318 NELL2 -0.64 -6.3 -0.49 4.64e-9 Gut microbiome composition (summer); TGCT cis rs1541995 1.000 rs11073450 chr15:96346544 A/T cg00882281 chr15:96346592 NA 0.29 4.8 0.4 4.46e-6 Photic sneeze reflex; TGCT cis rs9513593 1.000 rs747848 chr13:100036182 C/T cg21788972 chr13:99853209 UBAC2 0.56 4.68 0.39 7.51e-6 Psoriasis; TGCT cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs2019216 0.500 rs12938673 chr17:21941987 C/G cg22648282 chr17:21454238 C17orf51 -0.58 -4.95 -0.41 2.37e-6 Pelvic organ prolapse; TGCT cis rs9611565 0.659 rs73178632 chr22:41934573 C/T cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs7236492 0.688 rs73494217 chr18:77186200 G/A cg15644404 chr18:77186268 NFATC1 -0.35 -4.67 -0.39 7.83e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs910187 0.678 rs6018330 chr20:45813216 C/T cg27589058 chr20:45804311 EYA2 -0.36 -7.88 -0.58 1.44e-12 Migraine; TGCT cis rs3820928 0.605 rs2228555 chr2:227872995 C/T cg11843606 chr2:227700838 RHBDD1 0.51 4.71 0.39 6.47e-6 Pulmonary function; TGCT cis rs1552244 0.554 rs2272120 chr3:10046703 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs861020 0.677 rs12723578 chr1:210032392 G/A cg05527609 chr1:210001259 C1orf107 -0.93 -7.93 -0.58 1.09e-12 Orofacial clefts; TGCT cis rs6671200 1.000 rs933107 chr1:95672229 C/T cg26537280 chr1:95699037 RWDD3 -0.68 -5.49 -0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs775227 0.574 rs35274817 chr3:113266391 A/G cg18753928 chr3:113234510 CCDC52 -0.66 -4.45 -0.37 1.88e-5 Dental caries; TGCT cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.99 -7.28 -0.55 3.39e-11 Gut microbiome composition (summer); TGCT cis rs950169 0.959 rs66801143 chr15:84736657 C/T cg17173187 chr15:85201210 NMB 0.47 5.23 0.42 7.11e-7 Schizophrenia; TGCT cis rs12935418 0.616 rs62054238 chr16:80999650 T/C cg07676361 chr16:80966860 NA -0.35 -4.56 -0.38 1.19e-5 Mean corpuscular volume; TGCT cis rs7937682 0.960 rs480293 chr11:111469132 A/C cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT trans rs77457752 0.690 rs75036580 chr9:13912781 C/T cg18948646 chr4:83674694 SCD5;MIR575 0.54 6.62 0.51 9.53e-10 Breast cancer; TGCT cis rs28785552 0.589 rs11669056 chr19:53244443 G/A cg10871876 chr19:53194124 ZNF83 0.46 5.9 0.47 3.2e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs3806843 0.547 rs183679 chr5:140271017 C/T cg09824255 chr5:140014002 CD14 -0.27 -4.74 -0.39 5.73e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs10804591 1.000 rs6785282 chr3:129339500 C/G cg07730360 chr3:128845626 NA -0.19 -4.44 -0.37 1.99e-5 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs5769707 0.967 rs2187891 chr22:49994094 C/T cg10356904 chr22:49881777 NA -0.23 -4.76 -0.39 5.4e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg11502198 chr6:26597334 ABT1 0.54 4.87 0.4 3.4e-6 Intelligence (multi-trait analysis); TGCT cis rs6089584 0.888 rs6061979 chr20:60617141 C/G cg13770153 chr20:60521292 NA -0.54 -7.13 -0.54 7.45e-11 Body mass index; TGCT cis rs35883536 0.609 rs2647327 chr1:101041766 C/T cg10298815 chr1:101004474 GPR88 0.25 4.7 0.39 6.67e-6 Monocyte count; TGCT cis rs11690462 0.963 rs34918214 chr2:26628100 C/T cg04726446 chr2:26624865 C2orf39 0.42 4.52 0.38 1.45e-5 Coronary artery disease; TGCT cis rs3087591 0.708 rs7502834 chr17:29689430 G/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.64 0.45 1.08e-7 Hip circumference; TGCT cis rs709400 0.627 rs62007686 chr14:103899344 A/G cg12935359 chr14:103987150 CKB -0.36 -5.41 -0.44 3.09e-7 Body mass index; TGCT cis rs6540559 0.673 rs2357230 chr1:210019498 G/A cg22029157 chr1:209979665 IRF6 0.71 5.09 0.42 1.3e-6 Cleft lip with or without cleft palate; TGCT cis rs7296418 0.599 rs2277343 chr12:123794450 A/T cg00376283 chr12:123451042 ABCB9 0.62 5.32 0.43 4.7e-7 Platelet count; TGCT cis rs933688 1.000 rs332544 chr5:90778848 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.87 8.34 0.6 1.21e-13 Smoking behavior; TGCT cis rs13191362 1.000 rs67646369 chr6:163003233 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs79387448 0.745 rs17027496 chr2:103178223 T/A cg09003973 chr2:102972529 NA 0.97 6.24 0.49 6.29e-9 Gut microbiota (bacterial taxa); TGCT cis rs56104184 0.830 rs73061617 chr19:49350984 G/A cg15549821 chr19:49342101 PLEKHA4 -0.81 -9.48 -0.65 2.33e-16 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2637266 0.905 rs2395395 chr10:78360770 A/G cg18941641 chr10:78392320 NA 0.45 5.7 0.46 8.11e-8 Pulmonary function; TGCT cis rs11098499 0.863 rs7657849 chr4:120455494 T/C cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs6500602 0.727 rs10451135 chr16:4580214 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.97 0.47 2.35e-8 Schizophrenia; TGCT cis rs11785400 1.000 rs11776301 chr8:143737142 A/G cg10596483 chr8:143751796 JRK 0.59 6.38 0.5 3.27e-9 Schizophrenia; TGCT cis rs362272 0.524 rs10937924 chr4:3374898 T/C cg18352616 chr4:3374830 RGS12 0.25 4.97 0.41 2.16e-6 Serum sulfate level; TGCT cis rs2456568 0.803 rs10765642 chr11:93640355 C/T cg17595323 chr11:93583763 C11orf90 0.45 6.08 0.48 1.38e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs796364 0.806 rs11679658 chr2:200923081 A/G cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs1538970 0.924 rs11211117 chr1:45930246 C/T cg05343316 chr1:45956843 TESK2 0.75 6.27 0.49 5.48e-9 Platelet count; TGCT cis rs57590327 0.504 rs11712243 chr3:81840674 T/G cg07356753 chr3:81810745 GBE1 -0.73 -6.73 -0.52 5.57e-10 Extraversion; TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg06873352 chr17:61820015 STRADA 0.53 5.89 0.47 3.39e-8 Prudent dietary pattern; TGCT cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs6964587 1.000 rs10243241 chr7:91705696 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs11077998 1.000 rs11077998 chr17:80483946 C/G cg10255544 chr17:80519551 FOXK2 -0.24 -4.83 -0.4 3.92e-6 Reticulocyte fraction of red cells; TGCT cis rs769267 0.965 rs2269873 chr19:19392401 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs2153535 0.580 rs1335637 chr6:8465101 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs875971 0.830 rs4718358 chr7:65973668 T/C cg11764359 chr7:65958608 NA 0.61 5.56 0.45 1.55e-7 Aortic root size; TGCT cis rs9790314 0.905 rs7613358 chr3:160949296 T/C cg03342759 chr3:160939853 NMD3 -0.48 -5.23 -0.43 6.93e-7 Morning vs. evening chronotype; TGCT cis rs6089829 0.888 rs6011559 chr20:61675620 C/T cg08564027 chr20:61660810 NA -0.35 -5.53 -0.45 1.77e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7260538 0.808 rs2086785 chr19:41527085 T/C cg27089200 chr19:41531976 NA 0.43 5.39 0.44 3.39e-7 DDT metabolite (p,p'-DDE levels); TGCT cis rs295140 0.710 rs1729421 chr2:201080113 G/C cg04283868 chr2:201171347 SPATS2L -0.53 -5.19 -0.42 8.21e-7 QT interval; TGCT cis rs8179 0.645 rs56201652 chr7:92278116 G/A cg15732164 chr7:92237376 CDK6 -0.28 -4.8 -0.4 4.4e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs10992471 0.603 rs7872610 chr9:95299137 G/C cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.68 -0.45 9.01e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg11502198 chr6:26597334 ABT1 0.54 4.95 0.41 2.42e-6 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.800 rs35463363 chr4:17613423 G/T cg10189774 chr4:17578691 LAP3 0.66 5.47 0.44 2.36e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2074585 0.647 rs2601188 chr15:90929563 A/G cg22089800 chr15:90895588 ZNF774 -0.83 -9.17 -0.64 1.27e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs35306767 0.633 rs17221491 chr10:1065191 A/G cg18964960 chr10:1102726 WDR37 0.75 5.29 0.43 5.41e-7 Eosinophil percentage of granulocytes; TGCT cis rs4767364 0.569 rs1468253 chr12:112776042 C/T cg10833066 chr12:111807467 FAM109A -0.38 -5.61 -0.45 1.23e-7 Oral cavity and pharyngeal cancer; TGCT cis rs611744 0.870 rs685358 chr8:109161413 T/C cg21045802 chr8:109455806 TTC35 0.69 6.06 0.48 1.51e-8 Dupuytren's disease; TGCT cis rs2718812 0.719 rs1867505 chr3:133411052 T/C cg16414030 chr3:133502952 NA 0.4 5.23 0.43 6.91e-7 Iron status biomarkers; TGCT cis rs11264213 0.901 rs74879824 chr1:36413117 T/A cg27506609 chr1:36549197 TEKT2 0.42 4.72 0.39 6.2e-6 Schizophrenia; TGCT cis rs7267979 0.932 rs6107052 chr20:25530838 G/A cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2842992 0.789 rs2277072 chr6:160182845 A/G cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs7119038 0.865 rs11217046 chr11:118698907 G/A cg19308663 chr11:118741387 NA 0.3 5.88 0.47 3.49e-8 Sjögren's syndrome; TGCT cis rs5750830 0.649 rs5750818 chr22:39820885 A/G cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs9534288 0.700 rs57192057 chr13:46592327 C/G cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs2880765 0.835 rs1872074 chr15:86033184 T/G cg13263323 chr15:86062960 AKAP13 -0.22 -4.79 -0.4 4.68e-6 Coronary artery disease; TGCT cis rs76473307 0.661 rs78350375 chr20:57382520 A/G cg06163629 chr20:57414884 GNASAS;GNAS -0.66 -4.53 -0.38 1.39e-5 Chronic lymphocytic leukemia; TGCT cis rs5750830 0.649 rs5750811 chr22:39793066 G/T cg11247378 chr22:39784982 NA 0.68 9.02 0.63 2.97e-15 Intelligence (multi-trait analysis); TGCT cis rs7586879 0.681 rs6756609 chr2:25121125 C/A cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs929354 0.772 rs3802120 chr7:156977794 C/T cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs4455778 0.659 rs6972383 chr7:49022094 G/A cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs7552404 0.731 rs1770885 chr1:76402212 C/T cg10523679 chr1:76189770 ACADM -0.84 -7.83 -0.58 1.9e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1635 0.826 rs1233710 chr6:28215446 C/T cg15743358 chr6:28303923 ZNF323 -1.15 -4.78 -0.39 4.78e-6 Schizophrenia; TGCT cis rs10461617 0.592 rs6450403 chr5:56062737 A/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.2 -0.42 8.14e-7 Type 2 diabetes; TGCT cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg17328964 chr8:145687451 CYHR1 0.48 6.96 0.53 1.71e-10 Age at first birth; TGCT cis rs2439831 1.000 rs565007 chr15:43716641 A/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs12579753 1.000 rs17749267 chr12:82178308 A/G cg07988820 chr12:82153109 PPFIA2 0.62 6.54 0.51 1.43e-9 Resting heart rate; TGCT cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg06634786 chr22:41940651 POLR3H -0.89 -8.16 -0.59 3.16e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7178572 1.000 rs952471 chr15:77776498 C/G cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs7213347 0.707 rs4790323 chr17:2181658 A/G cg20777128 chr17:1945076 DPH1;OVCA2 -0.53 -4.79 -0.39 4.74e-6 Total body bone mineral density; TGCT cis rs10193935 1.000 rs13421289 chr2:42412808 T/C cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs950027 0.620 rs2467862 chr15:45643843 T/G cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs10465746 0.780 rs1871924 chr1:84398466 T/A cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT cis rs1018836 0.923 rs7826178 chr8:91649592 C/A cg16814680 chr8:91681699 NA -0.85 -8.82 -0.62 8.85e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2692947 0.770 rs72492163 chr2:96417816 G/A cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg10819733 chr22:24237672 NA -0.28 -4.58 -0.38 1.14e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3733585 0.699 rs6449202 chr4:9974043 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.62 -0.56 5.57e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7659604 0.840 rs6821305 chr4:122713863 A/C cg20573242 chr4:122745356 CCNA2 0.53 4.96 0.41 2.32e-6 Type 2 diabetes; TGCT cis rs17376456 0.825 rs28645862 chr5:93233128 G/C cg21475434 chr5:93447410 FAM172A 0.7 4.9 0.4 2.96e-6 Diabetic retinopathy; TGCT cis rs289997 1.000 rs981903 chr7:25574197 T/C cg14064488 chr7:26331273 SNX10 -0.33 -4.8 -0.4 4.47e-6 Breast cancer; TGCT cis rs12142240 0.698 rs28578741 chr1:46825176 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs9583531 0.657 rs7318291 chr13:111352460 C/T cg24331049 chr13:111365604 ING1 -0.9 -8.5 -0.61 5.17e-14 Coronary artery disease; TGCT cis rs4455778 0.538 rs6958308 chr7:49123900 C/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs2760061 0.846 rs3094912 chr1:228209815 T/A cg02753203 chr1:228287806 NA 0.32 6.26 0.49 5.64e-9 Diastolic blood pressure; TGCT cis rs7647973 0.961 rs4955417 chr3:49298205 T/C cg07636037 chr3:49044803 WDR6 0.67 5.41 0.44 3.15e-7 Menarche (age at onset); TGCT cis rs4699052 1.000 rs6533060 chr4:104139996 T/C cg16532752 chr4:104119610 CENPE -0.59 -5.63 -0.45 1.14e-7 Testicular germ cell tumor; TGCT cis rs7809950 0.678 rs12670688 chr7:106821016 A/G cg23024343 chr7:107201750 COG5 0.44 5.79 0.46 5.35e-8 Coronary artery disease; TGCT cis rs35146811 0.538 rs3823642 chr7:99796072 T/C cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.81 7.65 0.57 4.75e-12 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs11673344 0.523 rs2891766 chr19:37527959 C/A cg08039142 chr19:36980659 ZNF566 0.51 4.69 0.39 6.99e-6 Obesity-related traits; TGCT cis rs7192750 0.586 rs7204708 chr16:71986946 C/T cg06353428 chr16:71660113 MARVELD3 -0.74 -6.57 -0.51 1.25e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs68170813 0.559 rs75313693 chr7:106863170 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs72634258 0.554 rs12741937 chr1:7897622 A/T cg26816564 chr1:7831052 VAMP3 0.88 6.53 0.51 1.52e-9 Inflammatory bowel disease; TGCT cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg00786635 chr1:25594202 NA 0.57 5.97 0.47 2.38e-8 Erythrocyte sedimentation rate; TGCT cis rs910316 1.000 rs10138183 chr14:75615227 T/C cg11812906 chr14:75593930 NEK9 0.75 7.41 0.55 1.73e-11 Height; TGCT cis rs6964587 0.626 rs2106745 chr7:91506635 C/T cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs6061231 0.556 rs6121571 chr20:60977323 T/G cg15674680 chr20:60982522 CABLES2 0.68 5.56 0.45 1.61e-7 Colorectal cancer; TGCT cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg25036284 chr2:26402008 FAM59B -0.64 -5.13 -0.42 1.06e-6 Gut microbiome composition (summer); TGCT cis rs6089829 0.962 rs6089826 chr20:61668595 G/A cg08564027 chr20:61660810 NA 0.36 6.47 0.5 2.07e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs3924048 0.574 rs34494202 chr1:12612868 G/A cg00291366 chr1:12616550 NA 0.35 5.38 0.44 3.55e-7 Optic cup area; TGCT cis rs3020736 0.500 rs11090076 chr22:42514190 T/C cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg21724239 chr8:58056113 NA 0.48 5.12 0.42 1.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs7020830 0.830 rs13296413 chr9:37258105 C/T cg14294708 chr9:37120828 ZCCHC7 1.18 15.6 0.81 4.97e-31 Schizophrenia; TGCT cis rs6740322 0.643 rs13390381 chr2:43534414 C/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -5.86 -0.47 3.94e-8 Coronary artery disease; TGCT cis rs6450176 1.000 rs3776717 chr5:53298762 G/A ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2456568 0.548 rs4402256 chr11:93660803 T/C cg17595323 chr11:93583763 C11orf90 -0.44 -5.58 -0.45 1.42e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6840360 1.000 rs6845944 chr4:152604520 C/T cg17479576 chr4:152424074 FAM160A1 -0.46 -4.74 -0.39 5.8e-6 Intelligence (multi-trait analysis); TGCT cis rs62103177 0.525 rs10438902 chr18:77745640 A/G cg20368463 chr18:77673604 PQLC1 -0.43 -4.5 -0.37 1.56e-5 Opioid sensitivity; TGCT cis rs2836974 0.565 rs2836939 chr21:40578546 C/T cg11890956 chr21:40555474 PSMG1 0.89 6.88 0.53 2.59e-10 Cognitive function; TGCT cis rs1008375 1.000 rs10939740 chr4:17617490 T/C cg18681998 chr4:17616180 MED28 0.97 10.54 0.69 6.29e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7655441 1.000 rs13118694 chr4:80873106 G/C cg02241357 chr4:80885279 ANTXR2 -0.23 -4.46 -0.37 1.81e-5 Neutrophil percentage of white cells; TGCT cis rs11112613 0.713 rs68053161 chr12:105950035 G/C cg03607813 chr12:105948248 NA 0.52 6.0 0.47 2.03e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs9926296 0.682 rs467357 chr16:89717397 A/G cg04287289 chr16:89883240 FANCA -0.55 -5.06 -0.41 1.48e-6 Vitiligo; TGCT cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs8014204 0.836 rs11159099 chr14:75235397 A/G cg06637938 chr14:75390232 RPS6KL1 0.7 6.75 0.52 5.06e-10 Caffeine consumption; TGCT cis rs8141529 0.748 rs1318026 chr22:29283518 A/G cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs8017423 0.967 rs7147952 chr14:90720831 G/A cg04374321 chr14:90722782 PSMC1 0.77 7.82 0.57 2.02e-12 Mortality in heart failure; TGCT cis rs2243480 1.000 rs2460422 chr7:65601505 C/T cg20637647 chr7:64974828 NA 0.9 5.29 0.43 5.42e-7 Diabetic kidney disease; TGCT cis rs11098499 0.954 rs10006706 chr4:120409152 A/G cg09307838 chr4:120376055 NA 0.7 6.6 0.51 1.07e-9 Corneal astigmatism; TGCT cis rs4975709 0.610 rs4975705 chr5:1860359 T/C cg14773178 chr5:1868261 NA 0.34 5.77 0.46 6.08e-8 Cardiovascular disease risk factors; TGCT cis rs4919694 1.000 rs12245343 chr10:104774050 A/G cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs225245 0.782 rs225272 chr17:33969911 T/C cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.53e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg13395646 chr4:1353034 KIAA1530 -0.36 -4.62 -0.38 9.52e-6 Obesity-related traits; TGCT cis rs854765 0.618 rs8068820 chr17:17834119 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs4332037 0.539 rs55988458 chr7:2059761 G/A cg25834613 chr7:1915315 MAD1L1 -0.51 -4.99 -0.41 1.95e-6 Bipolar disorder; TGCT cis rs1008375 0.932 rs10029173 chr4:17659598 C/T cg18681998 chr4:17616180 MED28 -1.05 -12.0 -0.73 1.69e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.763 rs9988539 chr1:53213884 T/C cg24675658 chr1:53192096 ZYG11B 0.71 7.96 0.58 9.48e-13 Monocyte count; TGCT cis rs11673344 0.562 rs7250507 chr19:37586674 A/T cg08039142 chr19:36980659 ZNF566 0.5 4.68 0.39 7.49e-6 Obesity-related traits; TGCT cis rs2033711 0.503 rs7254299 chr19:58884965 A/G cg13691442 chr19:58878570 NA -0.2 -5.1 -0.42 1.24e-6 Uric acid clearance; TGCT cis rs7635838 0.619 rs347614 chr3:11276399 T/C cg00170343 chr3:11313890 ATG7 0.66 6.26 0.49 5.88e-9 HDL cholesterol; TGCT cis rs908922 0.676 rs3753451 chr1:152485227 T/G cg20991723 chr1:152506922 NA 0.47 6.65 0.51 8.33e-10 Hair morphology; TGCT cis rs4746818 1.000 rs10762259 chr10:70890929 C/T cg11621586 chr10:70884670 VPS26A 1.21 10.66 0.69 3.17e-19 Left atrial antero-posterior diameter; TGCT cis rs938554 0.513 rs4529048 chr4:9997112 G/T cg00071950 chr4:10020882 SLC2A9 0.68 5.11 0.42 1.19e-6 Blood metabolite levels; TGCT cis rs1403694 0.695 rs1851664 chr3:186436503 T/A cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs514406 0.861 rs12038438 chr1:53230581 A/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.41 -0.55 1.7e-11 Monocyte count; TGCT cis rs4665809 0.878 rs4143538 chr2:26290178 A/C cg22920501 chr2:26401640 FAM59B -0.74 -6.53 -0.51 1.55e-9 Gut microbiome composition (summer); TGCT cis rs7511006 0.859 rs7292228 chr22:50649560 C/G cg16473166 chr22:50639996 SELO 0.65 6.47 0.5 2e-9 Obesity-related traits; TGCT cis rs6461049 0.800 rs1860831 chr7:2160931 T/C cg22963979 chr7:1858916 MAD1L1 -0.41 -6.6 -0.51 1.08e-9 Schizophrenia; TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.83 -0.4 3.91e-6 Prudent dietary pattern; TGCT cis rs6815814 0.950 rs67719080 chr4:38787252 A/G cg02016764 chr4:38805732 TLR1 -0.31 -4.78 -0.39 4.9e-6 Breast cancer; TGCT cis rs9926296 0.605 rs8046243 chr16:89852133 A/G cg03388025 chr16:89894329 SPIRE2 0.51 8.89 0.62 5.95e-15 Vitiligo; TGCT cis rs769267 0.930 rs2304098 chr19:19646272 T/C cg08509172 chr19:19383838 TM6SF2 -0.35 -4.51 -0.38 1.46e-5 Tonsillectomy; TGCT cis rs2014572 1.000 rs3746231 chr19:57760057 G/A cg24459738 chr19:57751996 ZNF805 -0.57 -5.63 -0.45 1.17e-7 Hyperactive-impulsive symptoms; TGCT cis rs9419702 0.538 rs4074772 chr10:133540006 A/T cg20568497 chr10:133558893 NA 0.44 4.71 0.39 6.43e-6 Survival in rectal cancer; TGCT cis rs7552404 1.000 rs7524467 chr1:76194054 C/G cg22875332 chr1:76189707 ACADM 0.78 9.41 0.65 3.42e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9807989 0.801 rs7558339 chr2:102970243 T/G cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs3771570 1.000 rs4346380 chr2:242263223 G/A cg21155796 chr2:242212141 HDLBP 1.01 6.91 0.53 2.22e-10 Prostate cancer; TGCT cis rs8180040 0.676 rs7636252 chr3:47013542 T/G cg27129171 chr3:47204927 SETD2 0.73 9.42 0.65 3.15e-16 Colorectal cancer; TGCT cis rs9534288 0.797 rs7338189 chr13:46571035 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs2070488 0.965 rs3749386 chr3:38496065 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.95 10.55 0.69 5.82e-19 Electrocardiographic conduction measures; TGCT cis rs17221829 0.764 rs7930024 chr11:89386038 G/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg20637647 chr7:64974828 NA 0.97 5.6 0.45 1.29e-7 Diabetic kidney disease; TGCT cis rs3809566 0.963 rs3809565 chr15:63333619 A/G cg00520135 chr15:63333846 TPM1 -0.44 -5.44 -0.44 2.67e-7 Platelet count; TGCT cis rs4654899 0.629 rs2320590 chr1:21155195 C/T cg01072550 chr1:21505969 NA 0.53 8.47 0.61 5.83e-14 Superior frontal gyrus grey matter volume; TGCT cis rs2760061 0.626 rs2527615 chr1:228119283 A/G cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs861020 0.710 rs7516902 chr1:210022179 A/G cg05527609 chr1:210001259 C1orf107 1.03 9.06 0.63 2.29e-15 Orofacial clefts; TGCT cis rs4077468 0.927 rs1342063 chr1:205912859 C/T cg07157834 chr1:205819609 PM20D1 -0.31 -4.46 -0.37 1.83e-5 Cystic fibrosis-related diabetes; TGCT cis rs9682041 0.800 rs7643085 chr3:170070371 A/G cg07589077 chr3:170072950 NA 0.3 4.87 0.4 3.33e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs12134245 0.776 rs12124682 chr1:91995542 A/G cg07090678 chr1:91966139 CDC7 0.35 4.75 0.39 5.58e-6 Breast cancer; TGCT cis rs6728642 1.000 rs80303184 chr2:98024633 G/A cg26665480 chr2:98280029 ACTR1B -1.02 -5.02 -0.41 1.74e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT trans rs916888 0.687 rs199456 chr17:44797919 C/T cg22968622 chr17:43663579 NA 1.3 11.75 0.73 6.8e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7172809 0.573 rs55881066 chr15:77507674 T/C cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs7267979 0.844 rs6083824 chr20:25363057 G/A cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6867032 1.000 rs4975794 chr5:2015330 A/G cg26168224 chr5:2018326 NA -0.42 -7.44 -0.56 1.46e-11 Gut microbiome composition (winter); TGCT cis rs938554 0.578 rs7663032 chr4:9993838 C/T cg00071950 chr4:10020882 SLC2A9 0.55 5.22 0.42 7.29e-7 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs9921338 0.961 rs8060767 chr16:11370598 C/G cg00044050 chr16:11439710 C16orf75 -0.91 -6.23 -0.49 6.61e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs2832191 0.967 rs3787660 chr21:30520907 C/T cg24692254 chr21:30365293 RNF160 0.77 8.0 0.58 7.4e-13 Dental caries; TGCT trans rs1415174 0.916 rs2184835 chr1:87856243 G/T cg23065576 chr20:25207247 ENTPD6 -0.26 -6.83 -0.52 3.36e-10 Breast cancer; TGCT cis rs4788570 0.584 rs6499529 chr16:71715378 C/T cg06353428 chr16:71660113 MARVELD3 1.56 12.54 0.75 8.54e-24 Intelligence (multi-trait analysis); TGCT cis rs651907 1.000 rs662792 chr3:101599608 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.46 4.76 0.39 5.3e-6 Colorectal cancer; TGCT cis rs36051895 0.664 rs3780371 chr9:5095191 T/A cg02405213 chr9:5042618 JAK2 -0.72 -9.4 -0.65 3.59e-16 Pediatric autoimmune diseases; TGCT cis rs7843479 0.601 rs10453141 chr8:21847235 T/C cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.11e-12 Mean corpuscular volume; TGCT cis rs117785887 0.536 rs12203355 chr6:146384475 T/C cg06708562 chr6:146285465 SHPRH -0.85 -5.1 -0.42 1.25e-6 Interleukin-17 levels; TGCT cis rs10114408 0.959 rs10761302 chr9:96651133 T/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs12522290 0.947 rs76262184 chr5:152795311 A/T cg26893743 chr5:153749478 GALNT10 0.19 4.47 0.37 1.77e-5 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs3796352 0.667 rs34288509 chr3:52849493 G/C cg07884673 chr3:53033167 SFMBT1 0.58 4.83 0.4 3.95e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3806843 0.576 rs246072 chr5:140320426 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.11e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9807989 0.507 rs3213732 chr2:102998279 A/G cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg13695892 chr22:41940480 POLR3H -0.87 -8.24 -0.59 2.06e-13 Vitiligo; TGCT cis rs1997103 1.000 rs4948011 chr7:55403859 A/G cg17469321 chr7:55412551 NA 0.63 6.28 0.49 5.22e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6951245 0.935 rs79067319 chr7:1065548 C/T cg03188948 chr7:1209495 NA 0.55 4.56 0.38 1.2e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9467773 0.838 rs3734540 chr6:26463321 A/C cg15659132 chr6:26577336 NA 0.61 6.75 0.52 5.09e-10 Intelligence (multi-trait analysis); TGCT cis rs13202913 0.837 rs3734800 chr6:151766552 G/A cg03627880 chr6:151815985 C6orf97 -0.73 -5.42 -0.44 2.92e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg10117171 chr1:25599238 RHD -0.35 -5.76 -0.46 6.35e-8 Erythrocyte sedimentation rate; TGCT cis rs2980439 0.783 rs2948305 chr8:8098577 G/A cg15462221 chr8:8086144 FLJ10661 -0.58 -5.37 -0.43 3.66e-7 Neuroticism; TGCT cis rs427394 0.664 rs274722 chr5:6718668 C/T cg10857441 chr5:6722123 POLS -0.28 -7.07 -0.54 1e-10 Menopause (age at onset); TGCT cis rs4073582 0.595 rs801734 chr11:65931216 T/C cg16950941 chr11:66035639 RAB1B 0.55 5.42 0.44 2.94e-7 Gout; TGCT cis rs6088580 0.634 rs3736762 chr20:33037336 C/T cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs2235642 0.928 rs56289115 chr16:1608934 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.66 -0.39 8.12e-6 Coronary artery disease; TGCT cis rs7095607 0.785 rs10823142 chr10:69921335 T/A cg18986048 chr10:69913749 MYPN 0.45 5.16 0.42 9.71e-7 Lung function (FVC); TGCT cis rs17221829 0.965 rs12276507 chr11:89457053 T/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.88 -0.4 3.23e-6 Anxiety in major depressive disorder; TGCT cis rs1801251 0.893 rs11687128 chr2:233608901 T/C cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs78487399 0.908 rs6715003 chr2:43808659 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs62064224 0.765 rs11650584 chr17:30679330 T/G cg18200150 chr17:30822561 MYO1D 0.58 7.59 0.56 6.63e-12 Schizophrenia; TGCT cis rs10788264 0.621 rs7907952 chr10:124056774 C/T cg09507567 chr10:124027408 NA -0.4 -5.62 -0.45 1.19e-7 Total body bone mineral density; TGCT cis rs2836974 0.932 rs73221193 chr21:40554693 C/T cg11644478 chr21:40555479 PSMG1 1.02 10.63 0.69 3.73e-19 Cognitive function; TGCT cis rs7959452 0.684 rs11177615 chr12:69754189 G/A cg14784868 chr12:69753453 YEATS4 0.83 8.8 0.62 9.86e-15 Blood protein levels; TGCT cis rs7772486 0.790 rs80050589 chr6:146230454 T/C cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9796 0.689 rs7180494 chr15:41451841 T/C cg18705301 chr15:41695430 NDUFAF1 -0.5 -6.32 -0.49 4.26e-9 Menopause (age at onset); TGCT cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs4969178 0.600 rs4969184 chr17:76393413 G/A cg05887092 chr17:76393375 PGS1 0.22 4.66 0.39 8.18e-6 HDL cholesterol levels; TGCT cis rs11711311 0.712 rs6795099 chr3:113338782 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.69 -5.95 -0.47 2.58e-8 IgG glycosylation; TGCT cis rs9733 0.536 rs6661415 chr1:150635869 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs2153535 0.580 rs6926759 chr6:8456176 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10811516 0.501 rs10283707 chr9:21159810 G/A cg23029519 chr9:21187344 IFNA4 -0.28 -4.46 -0.37 1.83e-5 Response to mepolizumab in severe asthma; TGCT cis rs9486719 1.000 rs2472887 chr6:96865437 A/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs28386778 0.897 rs9906247 chr17:61857314 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs3796352 1.000 rs35507120 chr3:53053924 C/T cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7949030 0.653 rs2849030 chr11:62366986 G/A cg22862634 chr11:62369728 EML3;MTA2 -0.68 -8.7 -0.62 1.69e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs763014 0.898 rs1045277 chr16:633125 T/C cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6987853 0.966 rs2923439 chr8:42429122 A/G cg20539142 chr8:42623718 CHRNA6 -0.21 -5.16 -0.42 9.45e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg26513180 chr16:89883248 FANCA -0.71 -7.02 -0.53 1.29e-10 Vitiligo; TGCT cis rs7666738 0.830 rs6532724 chr4:99060993 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 0.690 rs4386800 chr6:66755242 A/G cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs35146811 0.700 rs4729579 chr7:99780282 C/G cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs7666738 0.830 rs10009943 chr4:99021475 G/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6988636 1.000 rs58189203 chr8:124184739 G/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs6490294 0.904 rs11066099 chr12:112392036 C/G cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.69e-8 Mean platelet volume; TGCT cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg11062466 chr8:58055876 NA 0.38 4.5 0.37 1.56e-5 Developmental language disorder (linguistic errors); TGCT cis rs9814567 0.752 rs7633868 chr3:134331048 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs8177253 0.901 rs9843728 chr3:133501407 C/T cg01448562 chr3:133502909 NA -0.34 -6.91 -0.53 2.2e-10 Iron status biomarkers; TGCT cis rs1975974 0.511 rs8078505 chr17:21755889 A/G cg18423549 chr17:21743878 NA -0.61 -5.45 -0.44 2.56e-7 Psoriasis; TGCT cis rs6964587 0.967 rs2040499 chr7:91809657 C/G cg17063962 chr7:91808500 NA -0.96 -11.12 -0.71 2.36e-20 Breast cancer; TGCT cis rs6969780 0.915 rs2107063 chr7:27167346 G/A cg04317399 chr7:27170313 HOXA4 -0.43 -4.62 -0.38 9.54e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6815814 0.808 rs11721824 chr4:38767749 G/A cg02016764 chr4:38805732 TLR1 -0.33 -5.25 -0.43 6.27e-7 Breast cancer; TGCT cis rs61612642 0.537 rs73434275 chr6:42156239 G/A cg01092361 chr6:42185687 MRPS10 0.93 6.53 0.51 1.56e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs2980439 0.607 rs2980419 chr8:8114141 A/T cg08975724 chr8:8085496 FLJ10661 0.66 6.05 0.48 1.61e-8 Neuroticism; TGCT cis rs7914558 0.966 rs12766205 chr10:104893568 A/G cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.66e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs8177253 1.000 rs6762719 chr3:133480817 A/G cg08048268 chr3:133502702 NA -0.65 -9.83 -0.66 3.21e-17 Iron status biomarkers; TGCT cis rs10490913 0.932 rs12246334 chr10:120150985 G/A cg23160142 chr10:120154512 NA 0.29 4.47 0.37 1.72e-5 Cancer; TGCT cis rs6463523 0.898 rs66892628 chr7:759374 T/A cg14391382 chr7:866102 UNC84A 0.2 4.58 0.38 1.13e-5 Subjective well-being; TGCT cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.56 4.97 0.41 2.19e-6 Height; TGCT cis rs2836950 0.520 rs59916147 chr21:40634702 T/G cg06238570 chr21:40685208 BRWD1 -0.62 -6.34 -0.49 3.91e-9 Menarche (age at onset); TGCT cis rs7959452 0.557 rs7980883 chr12:69778914 C/T cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs12458462 0.859 rs2242177 chr18:77477379 G/A cg11879182 chr18:77439856 CTDP1 0.69 7.74 0.57 3.03e-12 Monocyte count; TGCT cis rs7959452 0.535 rs11177577 chr12:69671791 C/T cg20891283 chr12:69753455 YEATS4 0.66 6.37 0.5 3.41e-9 Blood protein levels; TGCT cis rs7267979 1.000 rs2500448 chr20:25404027 A/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs916888 0.821 rs199505 chr17:44859410 A/G cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17102423 0.594 rs7159443 chr14:65550816 T/A cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.57e-9 Obesity-related traits; TGCT cis rs3771570 0.681 rs12151655 chr2:242281438 T/A cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs67311347 0.868 rs10865895 chr3:40378677 C/T cg13683864 chr3:40499215 RPL14 -1.1 -11.59 -0.72 1.72e-21 Renal cell carcinoma; TGCT cis rs6087771 0.682 rs2038397 chr20:30217759 A/G cg13852791 chr20:30311386 BCL2L1 0.8 6.93 0.53 2.06e-10 Subcortical brain region volumes;Putamen volume; TGCT cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg13695892 chr22:41940480 POLR3H 0.78 7.62 0.56 5.73e-12 Vitiligo; TGCT cis rs6988636 1.000 rs59834873 chr8:124188824 G/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs12497850 0.864 rs4955410 chr3:49181218 A/G cg16497277 chr3:49208875 KLHDC8B -0.49 -4.47 -0.37 1.72e-5 Parkinson's disease; TGCT cis rs9443645 0.810 rs7767711 chr6:79810700 G/A cg09184832 chr6:79620586 NA -0.45 -4.72 -0.39 6.23e-6 Intelligence (multi-trait analysis); TGCT trans rs9951602 0.512 rs1599633 chr18:76643526 T/C cg02800362 chr5:177631904 HNRNPAB 1.13 12.94 0.76 9.39e-25 Obesity-related traits; TGCT cis rs1534166 0.647 rs9876158 chr3:133508300 T/C cg16414030 chr3:133502952 NA 0.45 5.81 0.46 4.92e-8 Alcohol consumption (transferrin glycosylation); TGCT cis rs1371867 0.846 rs1660327 chr8:101292206 A/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg21951975 chr1:209979733 IRF6 0.77 9.63 0.65 1.02e-16 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs6570726 0.837 rs636894 chr6:145864122 T/C cg23711669 chr6:146136114 FBXO30 0.7 6.78 0.52 4.39e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs208520 0.770 rs2224422 chr6:66883993 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -10.21 -0.68 4.02e-18 Exhaled nitric oxide output; TGCT cis rs7904368 0.806 rs45495501 chr10:16861476 G/A cg14835575 chr10:16859367 RSU1 0.68 7.26 0.55 3.83e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg22920501 chr2:26401640 FAM59B -0.91 -6.42 -0.5 2.67e-9 Gut microbiome composition (summer); TGCT cis rs5769707 0.681 rs8137111 chr22:50043750 G/A cg06623630 chr22:50017776 C22orf34 -0.27 -4.67 -0.39 7.81e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg15687855 chr3:44754131 ZNF502 -0.44 -5.28 -0.43 5.72e-7 Depressive symptoms; TGCT cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg11062466 chr8:58055876 NA 0.44 4.6 0.38 1.03e-5 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.808 rs12104615 chr2:43676938 A/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9644630 0.897 rs17128525 chr8:19364006 C/T cg01280390 chr8:19363452 CSGALNACT1 -0.26 -4.67 -0.39 7.56e-6 Oropharynx cancer; TGCT cis rs2439831 0.681 rs956391 chr15:43617493 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.93 -7.07 -0.54 1e-10 Lung cancer in ever smokers; TGCT cis rs3087591 1.000 rs6505234 chr17:29688299 G/A cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.12 -0.54 7.88e-11 Hip circumference; TGCT trans rs2688608 0.620 rs11000767 chr10:75516626 G/T cg13918328 chr10:52500089 ASAH2B 0.67 6.83 0.52 3.39e-10 Inflammatory bowel disease; TGCT cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg16497277 chr3:49208875 KLHDC8B -0.49 -4.48 -0.37 1.66e-5 Parkinson's disease; TGCT cis rs8050907 0.744 rs1345430 chr16:4527961 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs6570726 0.738 rs6917199 chr6:145918320 G/A cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2762353 0.603 rs10946798 chr6:25781853 T/G cg12310025 chr6:25882481 NA 0.5 4.87 0.4 3.28e-6 Blood metabolite levels; TGCT cis rs6681544 0.544 rs1342128 chr1:82391756 A/G cg04226724 chr1:82268649 LPHN2 0.47 4.95 0.41 2.33e-6 Metabolite levels (X-11787); TGCT cis rs4566357 0.615 rs12621808 chr2:227909522 A/C cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT trans rs7819412 0.668 rs2409694 chr8:10946861 T/G cg06636001 chr8:8085503 FLJ10661 -0.81 -7.14 -0.54 7.1e-11 Triglycerides; TGCT cis rs6570726 0.791 rs2096201 chr6:145934273 C/T cg05347473 chr6:146136440 FBXO30 0.53 4.96 0.41 2.29e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2982552 0.903 rs2982555 chr6:152057656 A/C cg22157087 chr6:152012887 ESR1 0.2 4.88 0.4 3.21e-6 Bone properties (heel); TGCT cis rs2997447 0.706 rs17184877 chr1:26443908 A/T cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs9611565 0.559 rs5758397 chr22:42019251 C/T cg06634786 chr22:41940651 POLR3H 0.88 8.38 0.6 9.48e-14 Vitiligo; TGCT cis rs137699 1.000 rs137703 chr22:39750241 A/G cg05872129 chr22:39784769 NA -0.56 -4.65 -0.39 8.39e-6 IgG glycosylation; TGCT cis rs3784262 0.740 rs4646600 chr15:58295616 T/A cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.3 -0.49 4.77e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7959452 0.640 rs11177599 chr12:69721970 G/A cg20891283 chr12:69753455 YEATS4 0.66 6.62 0.51 9.6e-10 Blood protein levels; TGCT trans rs6951245 0.554 rs78999139 chr7:1138525 G/A cg13565492 chr6:43139072 SRF -0.82 -7.72 -0.57 3.43e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1568889 1.000 rs12800354 chr11:28047723 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.85 9.04 0.63 2.64e-15 Bipolar disorder; TGCT cis rs3806843 0.966 rs3806842 chr5:140212676 C/T cg19875535 chr5:140030758 IK 0.36 6.0 0.47 2.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.05 0.41 1.51e-6 Menopause (age at onset); TGCT cis rs9322193 0.961 rs2064520 chr6:149924786 A/T cg13206674 chr6:150067644 NUP43 0.53 4.65 0.39 8.33e-6 Lung cancer; TGCT cis rs9868809 0.772 rs9836462 chr3:48712791 C/T cg00383909 chr3:49044727 WDR6 -0.89 -5.52 -0.44 1.86e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT trans rs208520 0.837 rs208489 chr6:66927584 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.05 -0.67 9.41e-18 Exhaled nitric oxide output; TGCT cis rs9300255 0.602 rs10744147 chr12:123643729 A/G cg00376283 chr12:123451042 ABCB9 0.72 4.96 0.41 2.29e-6 Neutrophil percentage of white cells; TGCT cis rs587847 0.737 rs1520952 chr15:37668842 T/C cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs7586879 0.639 rs7567997 chr2:25096952 A/G cg01884057 chr2:25150051 NA 0.31 5.97 0.47 2.28e-8 Body mass index; TGCT trans rs288326 0.704 rs79576701 chr2:183704659 T/C cg06580014 chr4:25931115 C4orf52 0.68 6.8 0.52 3.96e-10 Blood protein levels; TGCT cis rs1878931 0.531 rs9635548 chr16:3417156 G/A cg05754148 chr16:3507555 NAT15 -0.33 -4.46 -0.37 1.82e-5 Body mass index (adult); TGCT cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg20637647 chr7:64974828 NA 0.93 5.2 0.42 8.11e-7 Diabetic kidney disease; TGCT cis rs12477438 0.520 rs6717723 chr2:99756930 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.47 0.86 2.08e-37 Chronic sinus infection; TGCT cis rs3849570 0.925 rs6765917 chr3:81891116 C/T cg07356753 chr3:81810745 GBE1 -0.72 -6.65 -0.51 8.21e-10 Waist circumference;Body mass index; TGCT cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs10782582 0.609 rs10873797 chr1:76377191 G/T cg10523679 chr1:76189770 ACADM -0.58 -5.24 -0.43 6.73e-7 Daytime sleep phenotypes; TGCT cis rs6088580 0.609 rs2378205 chr20:33110803 C/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs2836950 0.501 rs35994303 chr21:40686020 C/T cg11890956 chr21:40555474 PSMG1 -0.66 -6.17 -0.48 8.85e-9 Menarche (age at onset); TGCT cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg12311346 chr5:56204834 C5orf35 0.83 7.78 0.57 2.41e-12 Initial pursuit acceleration; TGCT cis rs7937612 1.000 rs11600703 chr11:120249287 C/T cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.53 -0.38 1.37e-5 Intraocular pressure; TGCT cis rs2880765 0.835 rs7180923 chr15:86050890 A/T cg13263323 chr15:86062960 AKAP13 -0.22 -4.79 -0.4 4.61e-6 Coronary artery disease; TGCT cis rs453301 0.631 rs28572014 chr8:8793607 C/T cg06636001 chr8:8085503 FLJ10661 -0.69 -5.92 -0.47 2.97e-8 Joint mobility (Beighton score); TGCT cis rs10507380 0.824 rs9512630 chr13:27918639 A/C cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs9868809 0.881 rs7620853 chr3:48666503 G/A cg00383909 chr3:49044727 WDR6 0.97 5.08 0.42 1.34e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs875971 0.862 rs35034167 chr7:65580166 C/G cg11764359 chr7:65958608 NA -0.53 -4.68 -0.39 7.26e-6 Aortic root size; TGCT trans rs1814175 0.645 rs1851853 chr11:49953434 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg06212747 chr3:49208901 KLHDC8B 0.66 6.18 0.49 8.29e-9 Menarche (age at onset); TGCT cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.52 -0.65 1.81e-16 Platelet count; TGCT cis rs28595532 0.920 rs115046587 chr4:119779604 T/C cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs17221829 0.733 rs12797439 chr11:89376199 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs4478858 0.746 rs10914328 chr1:31688406 A/G cg00250761 chr1:31883323 NA 0.28 4.76 0.39 5.19e-6 Alcohol dependence; TGCT cis rs1018836 0.608 rs6998106 chr8:91479755 G/T cg16814680 chr8:91681699 NA -0.71 -7.13 -0.54 7.28e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2797160 1.000 rs1739362 chr6:126020703 A/T cg05901451 chr6:126070800 HEY2 0.75 6.7 0.52 6.65e-10 Endometrial cancer; TGCT cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs3008870 1.000 rs912797 chr1:67413478 A/G cg11518657 chr1:67396239 MIER1 0.54 4.65 0.39 8.44e-6 Lymphocyte percentage of white cells; TGCT cis rs1218582 0.772 rs6699043 chr1:154913021 T/C cg03351412 chr1:154909251 PMVK 0.52 4.92 0.4 2.66e-6 Prostate cancer; TGCT cis rs1635 0.655 rs73742544 chr6:28317536 T/A cg24848467 chr6:28134517 ZNF389 -0.58 -4.7 -0.39 6.75e-6 Schizophrenia; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg11905131 chr22:24372483 LOC391322 -0.95 -11.1 -0.71 2.66e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12484776 0.786 rs11089973 chr22:40535657 A/G cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs9883204 1.000 rs9883204 chr3:123096820 T/C cg04890266 chr3:123102914 ADCY5 -0.37 -5.2 -0.42 7.84e-7 Birth weight; TGCT cis rs8016982 0.633 rs72695758 chr14:81720146 T/C cg01989461 chr14:81687754 GTF2A1 0.78 7.69 0.57 3.9e-12 Schizophrenia; TGCT cis rs28374715 0.662 rs72737793 chr15:41516823 C/T cg18705301 chr15:41695430 NDUFAF1 -0.78 -10.91 -0.7 7.59e-20 Ulcerative colitis; TGCT cis rs4237845 0.844 rs4628718 chr12:58301600 A/C cg02175503 chr12:58329896 NA 0.56 5.44 0.44 2.67e-7 Intelligence (multi-trait analysis); TGCT cis rs17601876 0.814 rs11632903 chr15:51564341 C/T cg19946085 chr15:51559439 CYP19A1 -0.34 -5.04 -0.41 1.59e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs68170813 0.559 rs59782202 chr7:107032766 G/T cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg24531977 chr5:56204891 C5orf35 -0.75 -7.39 -0.55 1.87e-11 Initial pursuit acceleration; TGCT cis rs11874712 0.527 rs6507664 chr18:43693615 T/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.49 4.86 0.4 3.47e-6 Migraine - clinic-based; TGCT cis rs6089829 0.926 rs1060491 chr20:61665817 C/A cg08564027 chr20:61660810 NA -0.36 -6.38 -0.5 3.22e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs2239547 0.603 rs6789219 chr3:53098938 C/G cg10802521 chr3:52805072 NEK4 -0.58 -5.36 -0.43 3.87e-7 Schizophrenia; TGCT cis rs9303401 0.659 rs11495824 chr17:56918882 C/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7953249 0.807 rs2393791 chr12:121423956 A/G cg02403541 chr12:121454288 C12orf43 0.52 4.61 0.38 9.94e-6 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs2228479 0.867 rs62052189 chr16:89975555 G/C cg19635926 chr16:89946313 TCF25 0.28 4.82 0.4 4.06e-6 Skin colour saturation; TGCT cis rs7666738 0.830 rs13129503 chr4:98987892 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9916302 0.784 rs34473775 chr17:37396201 G/T cg07936489 chr17:37558343 FBXL20 -0.64 -5.17 -0.42 9.21e-7 Glomerular filtration rate (creatinine); TGCT cis rs2013441 1.000 rs2263175 chr17:20128029 C/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs12478296 0.892 rs60042638 chr2:243038707 G/A cg06360820 chr2:242988706 NA -0.61 -4.75 -0.39 5.52e-6 Obesity-related traits; TGCT trans rs77457752 0.690 rs12352669 chr9:13911919 A/T cg12973904 chr7:149457885 NA -0.43 -6.86 -0.52 2.96e-10 Breast cancer; TGCT cis rs670523 0.532 rs6427297 chr1:155975493 C/T cg05700447 chr1:155978627 NA 0.24 5.26 0.43 5.99e-7 Inflammatory bowel disease;Crohn's disease; TGCT trans rs7628219 0.566 rs1344819 chr3:70757099 C/T cg00765653 chr20:57415144 GNASAS;GNAS 0.71 6.63 0.51 9.41e-10 Insomnia (caffeine-induced); TGCT cis rs60154123 0.541 rs76216762 chr1:210345621 A/G cg22029157 chr1:209979665 IRF6 0.73 4.51 0.38 1.48e-5 Coronary artery disease; TGCT cis rs1514658 0.903 rs2175971 chr4:119276829 C/G cg21605333 chr4:119757512 SEC24D -0.51 -4.51 -0.38 1.49e-5 Congenital heart disease (maternal effect); TGCT cis rs61990749 0.597 rs176980 chr14:78198449 C/G cg23188588 chr14:78226832 SNW1;C14orf178 -0.65 -4.59 -0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs7267979 0.789 rs6083820 chr20:25354178 G/A cg03522245 chr20:25566470 NINL -0.52 -5.23 -0.43 6.85e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7647973 1.000 rs6785045 chr3:49435243 G/C cg07636037 chr3:49044803 WDR6 -0.72 -5.79 -0.46 5.35e-8 Menarche (age at onset); TGCT cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg26818010 chr10:134567672 INPP5A -0.36 -4.76 -0.39 5.33e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs7618501 1.000 rs11130219 chr3:49752427 C/T cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs8017423 0.967 rs8016385 chr14:90721946 G/A cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs1421811 0.606 rs62369523 chr5:32713365 T/G cg16267343 chr5:32710456 NPR3 0.83 7.19 0.54 5.25e-11 Blood pressure; TGCT cis rs9858542 0.953 rs9841110 chr3:49492481 C/G cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg13397359 chr6:42928475 GNMT 0.73 6.54 0.51 1.45e-9 Plasma homocysteine levels (post-methionine load test); TGCT cis rs1385374 0.642 rs10847691 chr12:129287449 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.69 -0.39 6.99e-6 Systemic lupus erythematosus; TGCT cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg26818010 chr10:134567672 INPP5A -0.36 -5.09 -0.42 1.31e-6 Migraine; TGCT trans rs6089829 0.889 rs6062773 chr20:61663262 G/C cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs425277 1.000 rs262672 chr1:2080813 G/T cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs12360000 0.797 rs11250853 chr10:1909770 A/G cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs8014204 0.604 rs12147862 chr14:75384471 C/T cg06637938 chr14:75390232 RPS6KL1 -0.9 -9.23 -0.64 9.17e-16 Caffeine consumption; TGCT cis rs7089973 0.604 rs11196947 chr10:116601372 G/A cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9811920 0.665 rs1872609 chr3:99906579 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.39 4.69 0.39 6.98e-6 Axial length; TGCT cis rs62283056 0.512 rs752854 chr4:6281961 C/T cg14416269 chr4:6271139 WFS1 0.39 4.97 0.41 2.18e-6 Cisplatin-induced ototoxicity; TGCT cis rs2019216 0.521 rs12449447 chr17:21888786 C/T cg22648282 chr17:21454238 C17orf51 -0.55 -5.42 -0.44 2.97e-7 Pelvic organ prolapse; TGCT cis rs4240897 0.935 rs1474868 chr1:12044164 A/G cg13216073 chr1:12042593 MFN2 -0.2 -5.93 -0.47 2.82e-8 Tuberculosis; TGCT cis rs7819412 0.668 rs2409721 chr8:11038244 A/T cg21775007 chr8:11205619 TDH -0.51 -4.64 -0.38 8.59e-6 Triglycerides; TGCT cis rs155076 1.000 rs261407 chr13:21855213 C/A cg11317459 chr13:21872234 NA -1.33 -11.41 -0.72 4.71e-21 White matter hyperintensity burden; TGCT cis rs7829975 0.714 rs11784052 chr8:8671962 C/T cg15556689 chr8:8085844 FLJ10661 0.64 5.93 0.47 2.74e-8 Mood instability; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg22166914 chr1:53195759 ZYG11B 0.35 5.78 0.46 5.7e-8 Monocyte count; TGCT cis rs2070433 0.706 rs55696586 chr21:47733918 T/C cg12379764 chr21:47803548 PCNT 0.59 5.11 0.42 1.2e-6 Lymphocyte counts; TGCT cis rs8032315 0.965 rs35346340 chr15:91427872 G/C cg05211768 chr15:91427848 FES 0.49 4.93 0.41 2.54e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs40363 0.645 rs1690446 chr16:3519009 T/C cg22508957 chr16:3507546 NAT15 0.51 5.92 0.47 2.89e-8 Tuberculosis; TGCT trans rs17684571 0.938 rs35668437 chr6:56565856 C/A cg14229071 chr15:89282588 NA 0.52 6.82 0.52 3.54e-10 Schizophrenia; TGCT cis rs2070488 0.965 rs3762791 chr3:38568828 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT cis rs10504229 0.680 rs16921675 chr8:58052082 A/G cg08280861 chr8:58055591 NA 0.35 5.03 0.41 1.67e-6 Developmental language disorder (linguistic errors); TGCT cis rs9788682 0.747 rs2568488 chr15:78736593 T/A cg24631222 chr15:78858424 CHRNA5 -0.61 -4.55 -0.38 1.25e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs34734847 0.871 rs2239760 chr12:121163518 C/A cg21892295 chr12:121157589 UNC119B -0.24 -5.65 -0.45 1.02e-7 Mean corpuscular volume; TGCT trans rs35783704 1.000 rs35783704 chr8:105966258 G/A cg04212021 chr5:180231084 MGAT1 -0.55 -6.64 -0.51 8.79e-10 Systolic blood pressure; TGCT cis rs11754661 1.000 rs17349687 chr6:151207718 C/T cg01354656 chr6:151411710 MTHFD1L 0.46 4.8 0.4 4.42e-6 Alzheimer's disease (late onset); TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg18765753 chr7:1198926 ZFAND2A -0.51 -6.24 -0.49 6.39e-9 Longevity;Endometriosis; TGCT cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.94 9.46 0.65 2.58e-16 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.931 rs9876848 chr3:48844059 G/A cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT trans rs3780486 0.801 rs28517717 chr9:33179451 C/T cg20290983 chr6:43655470 MRPS18A 1.08 11.36 0.71 6.12e-21 IgG glycosylation; TGCT cis rs1552244 0.882 rs61429272 chr3:10037320 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs1218582 0.772 rs877343 chr1:154910012 A/G cg24250549 chr1:154909240 PMVK 0.62 6.28 0.49 5.29e-9 Prostate cancer; TGCT cis rs854765 0.693 rs12936037 chr17:17777245 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.75 -7.92 -0.58 1.12e-12 Total body bone mineral density; TGCT cis rs7647973 0.516 rs4308307 chr3:49193216 C/T cg07636037 chr3:49044803 WDR6 0.85 8.82 0.62 8.86e-15 Menarche (age at onset); TGCT cis rs77633900 0.614 rs280014 chr15:76986890 A/G cg21673338 chr15:77095150 SCAPER -0.5 -4.92 -0.4 2.68e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.79e-6 Obesity-related traits; TGCT cis rs992157 0.798 rs7557709 chr2:219167529 G/A cg00012203 chr2:219082015 ARPC2 0.79 7.99 0.58 8.08e-13 Colorectal cancer; TGCT cis rs7264396 0.790 rs10211771 chr20:34219994 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.27 -0.43 5.92e-7 Total cholesterol levels; TGCT cis rs6121246 0.821 rs6058448 chr20:30332396 C/T cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg20607798 chr8:58055168 NA 0.68 5.66 0.45 1e-7 Developmental language disorder (linguistic errors); TGCT cis rs10892173 0.678 rs7122817 chr11:117657679 A/G cg07621104 chr11:117668040 DSCAML1 0.51 5.47 0.44 2.36e-7 Myopia; TGCT cis rs116095464 0.558 rs7731089 chr5:290422 A/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT trans rs208520 0.690 rs207119 chr6:66786408 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs67385638 0.802 rs7119142 chr11:5309078 A/G cg12559170 chr11:5275217 HBG2 0.42 7.62 0.56 5.69e-12 Hemoglobin levels; TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.84e-11 Prudent dietary pattern; TGCT cis rs9952991 0.566 rs484020 chr18:12855440 G/A cg23544223 chr18:12777786 NA 0.54 4.71 0.39 6.43e-6 Inflammatory skin disease; TGCT cis rs950169 0.580 rs36126054 chr15:85177723 T/G cg11189052 chr15:85197271 WDR73 0.73 6.01 0.47 1.96e-8 Schizophrenia; TGCT cis rs9796 0.866 rs1678750 chr15:41410705 G/A cg18705301 chr15:41695430 NDUFAF1 -0.47 -6.1 -0.48 1.24e-8 Menopause (age at onset); TGCT cis rs17681684 0.565 rs62066045 chr17:9765023 T/C cg15743799 chr17:9805578 RCVRN -0.28 -5.84 -0.46 4.37e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs2074585 0.806 rs8033813 chr15:90999715 A/T cg22089800 chr15:90895588 ZNF774 0.76 8.12 0.59 3.92e-13 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs9303401 0.538 rs2240259 chr17:56458129 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.74 6.76 0.52 4.71e-10 Cognitive test performance; TGCT cis rs910316 0.737 rs28687415 chr14:75495482 T/C cg11812906 chr14:75593930 NEK9 0.59 5.59 0.45 1.38e-7 Height; TGCT cis rs7635838 0.751 rs9811658 chr3:11395833 A/G cg00170343 chr3:11313890 ATG7 0.64 6.21 0.49 7.42e-9 HDL cholesterol; TGCT cis rs9372253 0.967 rs9400379 chr6:110713783 A/G cg00083206 chr6:110721305 DDO -0.4 -5.94 -0.47 2.72e-8 Platelet distribution width; TGCT cis rs651907 0.535 rs13059470 chr3:101424800 A/G cg12386194 chr3:101231763 SENP7 -0.51 -5.0 -0.41 1.9e-6 Colorectal cancer; TGCT cis rs6543140 0.964 rs6543136 chr2:103065547 G/A cg09003973 chr2:102972529 NA 0.56 4.67 0.39 7.86e-6 Blood protein levels; TGCT cis rs4273100 0.541 rs7501702 chr17:19293727 C/T cg01534423 chr17:18965556 NA -0.75 -7.83 -0.58 1.83e-12 Schizophrenia; TGCT cis rs72949976 0.898 rs6732233 chr2:214022834 C/T cg08319019 chr2:214017104 IKZF2 -0.72 -6.91 -0.53 2.27e-10 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs66569888 0.507 rs11673736 chr2:106886935 T/C cg16099169 chr2:106886729 NA -0.47 -6.17 -0.48 9e-9 Facial morphology (factor 23); TGCT cis rs877282 0.853 rs11595510 chr10:756757 C/G cg17470449 chr10:769945 NA 0.29 4.77 0.39 4.98e-6 Uric acid levels; TGCT cis rs11190604 1.000 rs2495743 chr10:102329739 G/C cg16342193 chr10:102329863 NA -0.43 -5.39 -0.44 3.43e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2075371 0.966 rs2544214 chr7:133985736 G/A cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs78487399 0.808 rs113373412 chr2:43762987 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.79 4.82 0.4 4.14e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs75059851 0.756 rs7106806 chr11:133838837 G/C cg14047540 chr11:133829660 NA -0.58 -5.85 -0.46 4.17e-8 Schizophrenia; TGCT cis rs7017914 0.967 rs13272523 chr8:71641472 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs4927850 1.000 rs10881563 chr3:195750225 A/G cg02975922 chr3:195473998 MUC4 -0.23 -5.08 -0.42 1.35e-6 Pancreatic cancer; TGCT cis rs6977660 0.507 rs72591448 chr7:19775298 C/T cg05791153 chr7:19748676 TWISTNB 0.97 6.34 0.49 3.9e-9 Thyroid stimulating hormone; TGCT cis rs11190604 1.000 rs2489036 chr10:102319581 A/G cg23241863 chr10:102295624 HIF1AN 0.69 5.21 0.42 7.75e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs322458 0.568 rs470931 chr3:120626429 T/C cg21456320 chr3:121264201 POLQ -0.32 -4.52 -0.38 1.43e-5 Aging (facial); TGCT cis rs68170813 0.652 rs6976759 chr7:107158506 A/G cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs12422267 0.536 rs11246933 chr12:132610314 G/A cg09764611 chr12:132620959 NA -0.38 -5.71 -0.46 7.88e-8 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs6903823 0.508 rs1150721 chr6:28255040 G/C cg18815343 chr6:28367644 ZSCAN12 -0.44 -4.65 -0.39 8.28e-6 Pulmonary function; TGCT cis rs950027 0.596 rs2467853 chr15:45698793 T/G cg14582100 chr15:45693742 SPATA5L1 0.43 5.38 0.44 3.52e-7 Response to fenofibrate (adiponectin levels); TGCT cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg02458000 chr6:26745757 NA 0.51 4.77 0.39 5.08e-6 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.967 rs6823423 chr4:152604723 T/C cg17479576 chr4:152424074 FAM160A1 -0.46 -4.8 -0.4 4.53e-6 Intelligence (multi-trait analysis); TGCT cis rs763121 0.853 rs2205802 chr22:39046327 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs1218582 0.741 rs11264283 chr1:154869552 A/G cg16680214 chr1:154839983 KCNN3 -0.35 -7.05 -0.53 1.13e-10 Prostate cancer; TGCT cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs9902453 0.765 rs2729440 chr17:28106874 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg01802117 chr1:53393560 SCP2 -0.45 -5.42 -0.44 2.98e-7 Monocyte count; TGCT trans rs877282 0.945 rs34367686 chr10:791868 G/C cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs7465272 0.500 rs7463655 chr8:143731034 G/C cg10596483 chr8:143751796 JRK 0.53 5.21 0.42 7.5e-7 Bipolar disorder and schizophrenia; TGCT cis rs3796352 1.000 rs11718538 chr3:52975987 C/G cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs17711722 0.675 rs6947132 chr7:65273495 G/A cg00343986 chr7:65444356 GUSB -0.26 -6.14 -0.48 1.05e-8 Calcium levels; TGCT cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg06634786 chr22:41940651 POLR3H 0.89 8.81 0.62 9.46e-15 Vitiligo; TGCT cis rs7236492 0.683 rs79747802 chr18:77198964 C/T cg15644404 chr18:77186268 NFATC1 -0.35 -4.76 -0.39 5.22e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs6542838 0.611 rs1878589 chr2:99517979 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.66 -0.39 8.02e-6 Fear of minor pain; TGCT cis rs7772486 0.764 rs2265468 chr6:146218346 A/C cg23711669 chr6:146136114 FBXO30 0.9 10.54 0.69 6.03e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6733011 0.559 rs6711022 chr2:99449536 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.95 -0.41 2.37e-6 Bipolar disorder; TGCT cis rs929354 0.707 rs1182445 chr7:157024428 C/G cg05182265 chr7:156933206 UBE3C 0.4 9.05 0.63 2.54e-15 Body mass index; TGCT cis rs11098499 0.697 rs10016448 chr4:120298845 A/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs4819052 0.885 rs9980676 chr21:46665430 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.77 6.87 0.52 2.82e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6714710 0.603 rs956039 chr2:98416848 C/A cg26665480 chr2:98280029 ACTR1B 0.7 6.61 0.51 1.05e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg07061783 chr6:25882402 NA -0.68 -6.69 -0.52 6.73e-10 Intelligence (multi-trait analysis); TGCT cis rs3858526 0.959 rs11039723 chr11:5956002 G/C cg13902645 chr11:5959945 NA -0.44 -4.73 -0.39 6.06e-6 DNA methylation (variation); TGCT cis rs35306767 0.855 rs61830932 chr10:934183 T/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs2594989 0.887 rs2616535 chr3:11595167 A/G cg00170343 chr3:11313890 ATG7 0.66 4.6 0.38 1.03e-5 Circulating chemerin levels; TGCT cis rs4665809 1.000 rs2384321 chr2:26290054 A/G cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs734999 0.545 rs3890745 chr1:2553624 C/T cg18854424 chr1:2615690 NA -0.45 -5.02 -0.41 1.77e-6 Ulcerative colitis; TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.59 5.46 0.44 2.51e-7 Prudent dietary pattern; TGCT cis rs72945132 0.714 rs57320340 chr11:70160010 G/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs769267 0.965 rs2965188 chr19:19522557 G/A cg08509172 chr19:19383838 TM6SF2 -0.35 -4.63 -0.38 9.18e-6 Tonsillectomy; TGCT cis rs2224391 0.590 rs72813697 chr6:5274266 T/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -5.18 -0.42 8.9e-7 Height; TGCT cis rs16867321 0.570 rs73025489 chr2:181548425 A/G cg19218067 chr2:181235115 NA -0.42 -4.54 -0.38 1.34e-5 Obesity; TGCT cis rs2299587 0.698 rs2283113 chr8:17880243 C/A cg04898035 chr8:17640624 MTUS1 -0.21 -4.77 -0.39 5.09e-6 Economic and political preferences; TGCT cis rs3849570 1.000 rs13088000 chr3:81839404 T/C cg07356753 chr3:81810745 GBE1 -0.79 -7.16 -0.54 6.31e-11 Waist circumference;Body mass index; TGCT cis rs7267979 1.000 rs401166 chr20:25446308 C/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs651907 0.535 rs2290859 chr3:101525625 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.26 0.68 2.9e-18 Colorectal cancer; TGCT cis rs17253792 0.731 rs74823888 chr14:56049800 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs9911578 0.692 rs411988 chr17:56709034 G/A cg12560992 chr17:57184187 TRIM37 0.55 5.96 0.47 2.38e-8 Intelligence (multi-trait analysis); TGCT cis rs9383153 0.590 rs2072736 chr6:16328068 T/C cg06493612 chr6:15502050 JARID2 0.63 4.88 0.4 3.15e-6 Gambling; TGCT cis rs9436747 0.641 rs12042877 chr1:66053148 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.04 0.41 1.59e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs12477438 0.798 rs1530996 chr2:99584079 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.33 -0.49 4.13e-9 Chronic sinus infection; TGCT cis rs9467773 0.869 rs1796520 chr6:26410800 C/T cg09904177 chr6:26538194 HMGN4 -0.5 -4.62 -0.38 9.41e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg20607798 chr8:58055168 NA 0.44 4.52 0.38 1.44e-5 Developmental language disorder (linguistic errors); TGCT cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg11494091 chr17:61959527 GH2 0.42 7.28 0.55 3.36e-11 Height; TGCT cis rs858239 0.536 rs6956974 chr7:23252318 C/G cg05602783 chr7:23145260 KLHL7 0.67 5.77 0.46 5.83e-8 Cerebrospinal fluid biomarker levels; TGCT trans rs1814175 0.669 rs11040455 chr11:49669829 G/C cg03929089 chr4:120376271 NA -0.6 -6.88 -0.53 2.6e-10 Height; TGCT cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 8.56 0.61 3.72e-14 Platelet count; TGCT cis rs587847 0.708 rs34972991 chr15:37609380 G/A cg00216138 chr15:37171175 LOC145845 0.31 4.5 0.37 1.56e-5 Intraocular pressure; TGCT cis rs12142240 0.698 rs57267378 chr1:46816644 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs1971256 0.500 rs1971255 chr6:151816094 A/G cg14416726 chr6:151773293 C6orf211;RMND1 0.77 4.74 0.39 5.88e-6 Endometriosis; TGCT cis rs669446 0.591 rs636547 chr1:44106516 C/A cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs12579753 0.879 rs12579544 chr12:82164043 A/C cg07988820 chr12:82153109 PPFIA2 -0.69 -7.77 -0.57 2.56e-12 Resting heart rate; TGCT cis rs2032447 0.765 rs1935235 chr6:26067782 C/G cg07061783 chr6:25882402 NA -0.58 -5.6 -0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs858239 0.601 rs1034963 chr7:23148473 T/C cg05602783 chr7:23145260 KLHL7 -0.66 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs7666738 0.830 rs10007872 chr4:99001904 T/C cg05340658 chr4:99064831 C4orf37 0.49 5.6 0.45 1.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10088262 0.629 rs12541177 chr8:124800273 G/T cg20713898 chr8:124780851 FAM91A1 -0.84 -7.19 -0.54 5.3e-11 Pancreatic cancer; TGCT cis rs11190604 0.767 rs10883477 chr10:102161396 A/G cg16342193 chr10:102329863 NA -0.39 -5.02 -0.41 1.78e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7605378 0.658 rs4673507 chr2:200710167 G/C cg23649088 chr2:200775458 C2orf69 0.45 8.18 0.59 2.92e-13 Osteoporosis; TGCT cis rs875971 0.508 rs10253883 chr7:66061138 T/C cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs1153858 1.000 rs10444821 chr15:45647236 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs7428 0.527 rs1554110 chr2:85547963 C/T cg03728395 chr2:85555865 TGOLN2 -0.31 -5.17 -0.42 9.27e-7 Ear protrusion; TGCT cis rs78707713 0.512 rs12412776 chr10:71179502 G/A cg12610070 chr10:71211762 TSPAN15 -0.57 -6.41 -0.5 2.71e-9 Venous thromboembolism; TGCT cis rs9814567 1.000 rs9856693 chr3:134306913 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs875971 1.000 rs2220626 chr7:65546062 C/T cg11764359 chr7:65958608 NA -0.58 -4.99 -0.41 2.01e-6 Aortic root size; TGCT cis rs13242816 1.000 rs55977427 chr7:116110768 C/T cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs11030122 0.702 rs12223176 chr11:3982537 T/G cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs826838 0.510 rs10506129 chr12:39224242 A/T cg26384229 chr12:38710491 ALG10B 0.64 5.18 0.42 8.89e-7 Heart rate; TGCT cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg25036284 chr2:26402008 FAM59B -0.62 -4.94 -0.41 2.44e-6 Gut microbiome composition (summer); TGCT cis rs12580194 1.000 rs60206376 chr12:55703375 C/A cg20672549 chr12:56432144 IKZF4 0.27 4.45 0.37 1.92e-5 Cancer; TGCT cis rs736408 0.812 rs2270197 chr3:52824095 T/G cg10802521 chr3:52805072 NEK4 -0.66 -7.84 -0.58 1.74e-12 Bipolar disorder; TGCT cis rs922182 0.595 rs7176387 chr15:64219108 A/G cg02919090 chr15:64263738 DAPK2 -0.36 -6.43 -0.5 2.44e-9 Blood protein levels; TGCT cis rs10507380 0.824 rs75594604 chr13:27911116 G/A cg25543773 chr13:27185723 WASF3 0.34 4.89 0.4 3.02e-6 Electrocardiographic traits; TGCT cis rs7169223 0.653 rs1564499 chr15:79084808 C/T cg21242079 chr15:79101063 ADAMTS7 -0.29 -4.92 -0.4 2.71e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs9291683 0.595 rs11722930 chr4:10035454 G/A cg11266682 chr4:10021025 SLC2A9 0.64 8.92 0.63 5e-15 Bone mineral density; TGCT cis rs1153858 0.943 rs11070454 chr15:45680252 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs7833790 0.700 rs7825180 chr8:82723991 T/A cg06027949 chr8:82754900 SNX16 -0.65 -5.03 -0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs60843830 1.000 rs9213 chr2:218386 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.75 7.05 0.53 1.11e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs35883536 0.566 rs12566440 chr1:101095202 A/G cg06223162 chr1:101003688 GPR88 0.32 5.34 0.43 4.31e-7 Monocyte count; TGCT cis rs7666738 0.791 rs10005118 chr4:99038196 A/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28785552 0.536 rs10401689 chr19:53248430 T/G cg10871876 chr19:53194124 ZNF83 0.44 5.26 0.43 6.13e-7 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7614311 0.689 rs73120898 chr3:63828780 G/A cg22134162 chr3:63841271 THOC7 -0.38 -4.48 -0.37 1.64e-5 Lung function (FVC);Lung function (FEV1); TGCT cis rs6723226 0.767 rs10172308 chr2:32555760 G/A cg02381751 chr2:32503542 YIPF4 -0.57 -5.12 -0.42 1.15e-6 Intelligence (multi-trait analysis); TGCT trans rs7726839 0.540 rs72705102 chr5:659437 T/C cg11887960 chr12:57824829 NA 1.14 9.1 0.63 1.93e-15 Obesity-related traits; TGCT cis rs35883536 0.647 rs12023028 chr1:101042717 C/T cg14855972 chr1:101004472 GPR88 -0.24 -4.49 -0.37 1.64e-5 Monocyte count; TGCT cis rs2549003 0.870 rs10053046 chr5:131821558 A/G cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.92e-6 Asthma (sex interaction); TGCT cis rs2243480 1.000 rs34192067 chr7:65887657 C/A cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs10514758 0.744 rs78984868 chr3:114853930 C/T cg05943254 chr3:114009756 NA -0.85 -5.06 -0.41 1.48e-6 Urate levels in obese individuals; TGCT cis rs7528684 0.816 rs2210918 chr1:157692985 A/G cg17134153 chr1:157670328 FCRL3 -0.26 -4.69 -0.39 7e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg09323728 chr8:95962352 TP53INP1 -0.55 -7.07 -0.54 9.72e-11 Type 2 diabetes; TGCT cis rs6733011 0.582 rs6757099 chr2:99415235 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.52 -5.17 -0.42 9.04e-7 Bipolar disorder; TGCT cis rs4566357 0.615 rs12328876 chr2:227918899 G/T cg11843606 chr2:227700838 RHBDD1 -0.55 -5.26 -0.43 6.22e-7 Coronary artery disease; TGCT cis rs477895 0.838 rs12798333 chr11:64012784 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 6.93 0.53 2.04e-10 Mean platelet volume; TGCT cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg12436631 chr1:155007014 DCST1;DCST2 -0.27 -7.62 -0.56 5.57e-12 Schizophrenia; TGCT cis rs9733 0.519 rs7521898 chr1:150707596 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs10493773 0.609 rs10873716 chr1:86178347 G/T cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg10560079 chr2:191398806 TMEM194B -0.36 -5.07 -0.41 1.4e-6 Pulse pressure; TGCT cis rs17767294 0.614 rs72850298 chr6:28222556 G/A cg08851530 chr6:28072375 NA 1.54 6.89 0.53 2.51e-10 Parkinson's disease; TGCT cis rs3806843 0.521 rs246061 chr5:140324656 C/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs1008375 0.835 rs13122181 chr4:17708815 C/A cg18681998 chr4:17616180 MED28 -0.84 -8.54 -0.61 4.13e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2228479 0.557 rs62054639 chr16:89821489 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs2073300 0.793 rs75758241 chr20:23434696 A/G cg09953122 chr20:23471693 CST8 -0.61 -4.52 -0.38 1.4e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs651907 0.535 rs11716558 chr3:101528481 T/C cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.52 -0.51 1.56e-9 Colorectal cancer; TGCT trans rs629535 0.954 rs559245 chr8:70009238 T/A cg21567404 chr3:27674614 NA -0.56 -8.41 -0.6 8.26e-14 Dupuytren's disease; TGCT cis rs40363 0.645 rs250629 chr16:3525431 C/A cg05754148 chr16:3507555 NAT15 0.43 5.17 0.42 9.15e-7 Tuberculosis; TGCT cis rs4700695 0.719 rs27078 chr5:65445331 G/C cg21114390 chr5:65439923 SFRS12 -0.84 -7.45 -0.56 1.35e-11 Facial morphology (factor 19); TGCT cis rs344364 0.511 rs2982433 chr16:1954508 A/G cg26617929 chr16:1858877 NA -0.24 -4.61 -0.38 9.87e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9911578 0.967 rs72628392 chr17:56506160 A/G cg05425664 chr17:57184151 TRIM37 0.62 6.16 0.48 9.42e-9 Intelligence (multi-trait analysis); TGCT trans rs10203711 1.000 rs4994753 chr2:239567253 T/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 1.000 rs7573118 chr2:26308086 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs6714710 0.535 rs3192177 chr2:98354511 G/A cg26665480 chr2:98280029 ACTR1B 0.63 5.63 0.45 1.14e-7 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs6671200 0.607 rs7528790 chr1:95709074 A/G cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs8177253 0.965 rs4854761 chr3:133498789 A/G cg20276088 chr3:133502917 NA 0.26 5.43 0.44 2.82e-7 Iron status biomarkers; TGCT cis rs11118844 0.744 rs4623704 chr1:221953846 G/A cg04222084 chr1:221915650 DUSP10 -0.8 -4.83 -0.4 3.89e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs2066819 1.000 rs77853814 chr12:56687572 G/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg18867708 chr6:26865862 GUSBL1 -0.39 -5.16 -0.42 9.66e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11098499 0.863 rs3775847 chr4:120447642 A/C cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs910316 0.763 rs12588981 chr14:75460561 A/G cg11812906 chr14:75593930 NEK9 0.58 5.56 0.45 1.6e-7 Height; TGCT cis rs2050392 0.799 rs2907 chr10:30728250 A/G cg13289132 chr10:30722225 MAP3K8 -0.41 -4.97 -0.41 2.15e-6 Inflammatory bowel disease; TGCT trans rs459571 0.920 rs460154 chr9:136909309 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.69 -7.36 -0.55 2.2e-11 Platelet distribution width; TGCT cis rs36051895 0.632 rs12340617 chr9:5164492 G/C cg02405213 chr9:5042618 JAK2 -0.72 -9.27 -0.64 7.51e-16 Pediatric autoimmune diseases; TGCT cis rs17376456 0.597 rs1031423 chr5:93276883 A/G cg25358565 chr5:93447407 FAM172A -0.62 -5.85 -0.47 4.08e-8 Diabetic retinopathy; TGCT cis rs7914558 1.000 rs7896547 chr10:104866958 A/G cg04362960 chr10:104952993 NT5C2 0.63 5.64 0.45 1.07e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs624899 0.522 rs645584 chr19:11612466 A/G cg04328562 chr19:11649701 CNN1 0.44 4.6 0.38 1.02e-5 Presence of antiphospholipid antibodies; TGCT cis rs514406 0.505 rs6688064 chr1:53165609 C/T cg24675658 chr1:53192096 ZYG11B -0.74 -8.3 -0.6 1.52e-13 Monocyte count; TGCT cis rs2147959 0.714 rs6659690 chr1:228628170 A/G cg22700015 chr1:228743131 NA -0.57 -4.53 -0.38 1.35e-5 Adult asthma; TGCT cis rs9611565 0.649 rs5758434 chr22:42116163 G/A cg06481639 chr22:41940642 POLR3H 0.56 4.87 0.4 3.39e-6 Vitiligo; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg18538332 chr22:24372958 LOC391322 -0.99 -12.78 -0.75 2.24e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs875971 0.965 rs6971509 chr7:65714970 G/T cg18876405 chr7:65276391 NA -0.32 -4.92 -0.4 2.72e-6 Aortic root size; TGCT cis rs6669072 0.669 rs814545 chr1:91240551 C/G cg08895590 chr1:91227319 NA -0.34 -4.5 -0.37 1.57e-5 Cognitive function; TGCT cis rs10883723 0.810 rs7074343 chr10:104283165 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7949030 0.626 rs61296092 chr11:62320838 T/C cg11742103 chr11:62369870 EML3;MTA2 0.61 8.75 0.62 1.31e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2549003 1.000 rs7735073 chr5:131815357 G/A cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs7226408 0.857 rs8099118 chr18:34593699 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2688608 0.592 rs7909802 chr10:75484186 G/C cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs12142240 0.698 rs6683192 chr1:46830257 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.8 -0.4 4.46e-6 Menopause (age at onset); TGCT cis rs7027203 0.828 rs4744291 chr9:96598297 A/G cg14396892 chr9:96623032 NA -0.26 -5.46 -0.44 2.51e-7 DNA methylation (variation); TGCT cis rs74181299 0.964 rs2540949 chr2:65284231 A/T cg05010058 chr2:65284262 CEP68 0.43 4.85 0.4 3.61e-6 Pulse pressure; TGCT cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg06634786 chr22:41940651 POLR3H 0.88 8.73 0.62 1.44e-14 Vitiligo; TGCT cis rs12410462 0.502 rs115241368 chr1:227795465 A/G cg23173402 chr1:227635558 NA 0.67 4.58 0.38 1.11e-5 Major depressive disorder; TGCT cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg13342137 chr4:2252803 MXD4 0.17 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs7809950 0.822 rs2712228 chr7:107300340 A/C cg23024343 chr7:107201750 COG5 0.29 4.78 0.39 4.94e-6 Coronary artery disease; TGCT cis rs12935418 0.524 rs9933697 chr16:80973534 A/G cg07676361 chr16:80966860 NA -0.32 -4.57 -0.38 1.18e-5 Mean corpuscular volume; TGCT cis rs9653442 0.545 rs4851252 chr2:100757280 C/T cg07810366 chr2:100720526 AFF3 -0.39 -5.63 -0.45 1.17e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs42648 0.777 rs4728878 chr7:89924232 T/G cg25739043 chr7:89950458 NA -0.73 -7.32 -0.55 2.79e-11 Homocysteine levels; TGCT cis rs9297145 0.916 rs4236540 chr7:98769025 A/C cg05967295 chr7:98741636 SMURF1 1.03 16.21 0.82 1.99e-32 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs6570726 0.818 rs437147 chr6:145875423 A/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9303401 0.659 rs7216648 chr17:56790858 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs1008375 0.966 rs11737844 chr4:17697421 A/C cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9929218 0.551 rs2296406 chr16:68721340 G/A cg01251360 chr16:68772225 CDH1 -0.25 -4.63 -0.38 8.9e-6 Colorectal cancer; TGCT cis rs12682352 0.602 rs6993494 chr8:8667444 C/T cg06636001 chr8:8085503 FLJ10661 0.61 5.1 0.42 1.26e-6 Neuroticism; TGCT cis rs933688 1.000 rs6452953 chr5:90723034 T/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.23 0.59 2.24e-13 Smoking behavior; TGCT cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg06697600 chr4:7070879 GRPEL1 -0.47 -4.94 -0.41 2.42e-6 Monocyte percentage of white cells; TGCT cis rs801193 1.000 rs2659889 chr7:66217112 A/G cg00343986 chr7:65444356 GUSB 0.24 5.26 0.43 6.15e-7 Aortic root size; TGCT cis rs9549367 0.789 rs71446679 chr13:113894821 C/T cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs12579753 0.672 rs4509857 chr12:82268017 C/T cg07988820 chr12:82153109 PPFIA2 -0.42 -4.44 -0.37 1.97e-5 Resting heart rate; TGCT cis rs7178572 0.568 rs4886856 chr15:77510585 A/G cg22256960 chr15:77711686 NA -0.87 -8.87 -0.62 6.78e-15 Type 2 diabetes; TGCT cis rs28735056 0.596 rs3744879 chr18:77679006 G/C cg16244155 chr18:77905565 LOC100130522 -0.39 -4.53 -0.38 1.39e-5 Schizophrenia; TGCT cis rs909674 0.865 rs5757682 chr22:39848259 T/G cg05872129 chr22:39784769 NA -0.99 -9.89 -0.66 2.4e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg22764044 chr5:178986830 RUFY1 -0.52 -5.98 -0.47 2.21e-8 Lung cancer; TGCT cis rs28785552 0.931 rs8113078 chr19:53239084 T/G cg04754360 chr19:53238445 ZNF611 -0.66 -5.32 -0.43 4.67e-7 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs3617 0.572 rs2256332 chr3:52855865 A/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.5 -4.76 -0.39 5.23e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs600231 0.706 rs10896016 chr11:65335705 C/T cg13974409 chr11:65292307 SCYL1 -0.45 -4.53 -0.38 1.35e-5 Bone mineral density; TGCT cis rs13118159 0.573 rs4974618 chr4:1373663 C/T cg05025164 chr4:1340916 KIAA1530 0.68 5.64 0.45 1.11e-7 Longevity; TGCT cis rs12643440 0.574 rs62296689 chr4:17139096 G/C cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs6964587 1.000 rs6946356 chr7:91727385 G/A cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs6489785 0.509 rs3213570 chr12:121222411 C/G cg02419362 chr12:121203948 SPPL3 0.19 4.47 0.37 1.74e-5 Longevity;Allergic disease (asthma, hay fever or eczema); TGCT cis rs7017914 0.967 rs62530792 chr8:71618767 T/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.13 -0.42 1.11e-6 Bone mineral density; TGCT cis rs6988636 1.000 rs28542077 chr8:124190896 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs12900413 0.603 rs2351493 chr15:90299536 A/G cg24249390 chr15:90295951 MESP1 -0.29 -5.03 -0.41 1.7e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs4072705 0.614 rs35929043 chr9:127234356 T/C cg13476313 chr9:127244764 NR5A1 0.29 4.49 0.37 1.64e-5 Menarche (age at onset); TGCT cis rs7100689 0.753 rs4934125 chr10:82147466 T/C cg01528321 chr10:82214614 TSPAN14 0.86 8.47 0.61 5.9e-14 Post bronchodilator FEV1; TGCT cis rs6582630 0.502 rs11614397 chr12:38328163 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs4665809 0.818 rs35413760 chr2:26267137 C/A cg04944784 chr2:26401820 FAM59B 0.7 5.71 0.46 7.94e-8 Gut microbiome composition (summer); TGCT cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.94 10.0 0.67 1.29e-17 Intelligence (multi-trait analysis); TGCT cis rs4253772 0.513 rs9615345 chr22:46713631 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.74 5.37 0.43 3.66e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs71435601 0.600 rs312981 chr2:21378151 G/A cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs6952808 0.825 rs12669937 chr7:1939765 C/T cg04267008 chr7:1944627 MAD1L1 -0.38 -4.93 -0.4 2.55e-6 Bipolar disorder and schizophrenia; TGCT cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg11890956 chr21:40555474 PSMG1 0.81 7.98 0.58 8.45e-13 Cognitive function; TGCT trans rs10504390 0.656 rs17302765 chr8:66474459 A/G cg18118147 chr19:51128640 SYT3 -0.77 -6.81 -0.52 3.71e-10 IgG glycosylation; TGCT cis rs4839827 1 rs4839827 chr6:96853967 C/T cg18709589 chr6:96969512 KIAA0776 0.52 4.84 0.4 3.72e-6 Migraine; TGCT cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs9796 0.870 rs2925346 chr15:41315695 G/A cg18705301 chr15:41695430 NDUFAF1 0.41 5.33 0.43 4.57e-7 Menopause (age at onset); TGCT cis rs1218582 0.772 rs4845400 chr1:154872523 C/T cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs709400 0.597 rs1013650 chr14:103909203 G/A cg12935359 chr14:103987150 CKB -0.33 -4.84 -0.4 3.86e-6 Body mass index; TGCT trans rs6762477 0.748 rs9831967 chr3:50217234 C/T cg21659725 chr3:3221576 CRBN -0.7 -7.99 -0.58 7.75e-13 Menarche (age at onset); TGCT cis rs4700695 0.719 rs36922 chr5:65464856 C/T cg21114390 chr5:65439923 SFRS12 -0.82 -6.8 -0.52 4.03e-10 Facial morphology (factor 19); TGCT cis rs13256369 0.851 rs13267036 chr8:8566685 G/A cg17143192 chr8:8559678 CLDN23 0.58 5.41 0.44 3.15e-7 Obesity-related traits; TGCT cis rs7439150 0.954 rs2227395 chr4:155484511 G/A cg22130008 chr4:155548532 NA -0.47 -5.8 -0.46 5.25e-8 Fibrinogen levels; TGCT cis rs13217239 0.646 rs4403259 chr6:26997617 C/T cg15659132 chr6:26577336 NA 0.54 5.44 0.44 2.78e-7 Schizophrenia; TGCT cis rs854572 1.000 rs854572 chr7:94954696 C/G cg21856205 chr7:94953877 PON1 -0.73 -8.46 -0.61 6.15e-14 Paraoxonase activity; TGCT cis rs7666738 0.830 rs2903154 chr4:99048151 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9291683 0.530 rs4235346 chr4:9945296 C/T cg11266682 chr4:10021025 SLC2A9 -0.62 -8.01 -0.58 7.07e-13 Bone mineral density; TGCT cis rs7020830 0.789 rs17408112 chr9:37114065 A/G cg14294708 chr9:37120828 ZCCHC7 1.31 20.37 0.88 2.24e-41 Schizophrenia; TGCT cis rs9952991 0.941 rs1893217 chr18:12809340 A/G cg23544223 chr18:12777786 NA -0.59 -5.3 -0.43 5.14e-7 Inflammatory skin disease; TGCT cis rs854765 0.583 rs7214536 chr17:17852446 G/A cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.16 0.54 6.32e-11 Prudent dietary pattern; TGCT cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg13683864 chr3:40499215 RPL14 -1.08 -11.45 -0.72 3.78e-21 Renal cell carcinoma; TGCT cis rs950169 0.881 rs62029596 chr15:84955434 A/G cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs2180341 0.883 rs7760748 chr6:127690062 C/T cg27446573 chr6:127587934 RNF146 1.1 10.61 0.69 4.22e-19 Breast cancer; TGCT cis rs67478160 0.584 rs2295148 chr14:104195610 T/C cg26031613 chr14:104095156 KLC1 -0.77 -7.66 -0.57 4.63e-12 Schizophrenia; TGCT cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs9640161 0.659 rs7781827 chr7:150008858 T/C cg10018233 chr7:150070692 REPIN1 0.31 4.44 0.37 1.96e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs72945132 0.709 rs28634008 chr11:70225719 A/C cg00319359 chr11:70116639 PPFIA1 1.02 7.54 0.56 8.61e-12 Coronary artery disease; TGCT cis rs425277 0.606 rs2503705 chr1:2076741 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.37 -5.2 -0.42 8.04e-7 Height; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs1371867 0.817 rs1788208 chr8:101312515 T/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg25151919 chr3:44754333 ZNF502 -0.39 -4.57 -0.38 1.15e-5 Depressive symptoms; TGCT cis rs8141529 0.644 rs5752795 chr22:29178820 T/C cg02153584 chr22:29168773 CCDC117 0.74 6.25 0.49 5.89e-9 Lymphocyte counts; TGCT cis rs4901869 0.966 rs9972208 chr14:59336116 C/T cg02291164 chr14:59296302 NA 0.24 4.69 0.39 7.18e-6 Panic disorder; TGCT cis rs11264213 0.901 rs72661631 chr1:36417453 A/G cg27506609 chr1:36549197 TEKT2 0.42 4.72 0.39 6.2e-6 Schizophrenia; TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg21672276 chr3:44754072 ZNF502 -0.41 -4.62 -0.38 9.62e-6 Depressive symptoms; TGCT cis rs2120019 1.000 rs7173833 chr15:75369618 C/T cg11632617 chr15:75315747 PPCDC -0.33 -4.64 -0.38 8.77e-6 Blood trace element (Zn levels); TGCT cis rs769267 0.895 rs1000237 chr19:19518316 T/A cg03709012 chr19:19516395 GATAD2A 0.75 6.51 0.5 1.71e-9 Tonsillectomy; TGCT cis rs2153535 0.580 rs7747306 chr6:8453663 C/G cg07606381 chr6:8435919 SLC35B3 -0.53 -5.04 -0.41 1.64e-6 Motion sickness; TGCT cis rs36051895 0.632 rs12684720 chr9:5150800 T/C cg02405213 chr9:5042618 JAK2 -0.75 -9.81 -0.66 3.66e-17 Pediatric autoimmune diseases; TGCT cis rs9486719 0.947 rs2499801 chr6:96854594 G/A cg18709589 chr6:96969512 KIAA0776 0.68 4.93 0.4 2.63e-6 Migraine;Coronary artery disease; TGCT cis rs208520 0.690 rs12197578 chr6:66725905 C/T cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs631288 0.557 rs894467 chr1:146662018 C/T cg25205988 chr1:146714368 CHD1L 1.34 5.37 0.43 3.79e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs2227564 0.620 rs4746148 chr10:75534488 C/T cg19442545 chr10:75533431 FUT11 -0.3 -4.47 -0.37 1.77e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6882046 0.513 rs651666 chr5:88048767 A/G cg24804195 chr5:87968844 LOC645323 -0.58 -5.68 -0.45 9.18e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs7666738 0.830 rs7696568 chr4:99005333 A/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.922 rs67804993 chr15:85104030 T/G cg17173187 chr15:85201210 NMB 0.53 5.53 0.44 1.83e-7 Schizophrenia; TGCT cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg25036284 chr2:26402008 FAM59B -0.6 -4.81 -0.4 4.25e-6 Gut microbiome composition (summer); TGCT cis rs7567389 0.534 rs72845982 chr2:128098570 G/A cg09760422 chr2:128146352 NA 0.39 5.18 0.42 8.76e-7 Self-rated health; TGCT cis rs2439831 0.867 rs16957632 chr15:43642897 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs7772486 0.754 rs702318 chr6:146005873 G/T cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6988636 0.536 rs16898043 chr8:124155886 A/G cg22384356 chr8:124195192 FAM83A -0.42 -4.84 -0.4 3.73e-6 Urinary uromodulin levels; TGCT cis rs78456975 0.739 rs13405352 chr2:1518726 C/T cg01028140 chr2:1542097 TPO -0.35 -4.71 -0.39 6.58e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7772486 0.719 rs4391282 chr6:146276780 A/T cg05347473 chr6:146136440 FBXO30 -0.52 -5.1 -0.42 1.26e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4073582 0.595 rs528842 chr11:66032390 G/A cg16950941 chr11:66035639 RAB1B 0.58 5.44 0.44 2.67e-7 Gout; TGCT cis rs11203032 0.831 rs2902445 chr10:90934154 A/G cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg22029157 chr1:209979665 IRF6 0.77 6.36 0.5 3.47e-9 Cleft lip with or without cleft palate; TGCT cis rs2549003 1.000 rs17848418 chr5:131821188 C/T cg21138405 chr5:131827807 IRF1 0.19 4.79 0.4 4.64e-6 Asthma (sex interaction); TGCT cis rs7524258 0.835 rs75096060 chr1:7270248 G/C cg07173049 chr1:7289937 CAMTA1 0.29 4.89 0.4 3.01e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7833790 0.777 rs7815272 chr8:82691809 T/G cg27398817 chr8:82754497 SNX16 -0.83 -5.96 -0.47 2.43e-8 Diastolic blood pressure; TGCT cis rs1982963 0.950 rs1566132 chr14:52511836 C/T cg10843707 chr14:52510701 NID2 -0.44 -6.81 -0.52 3.72e-10 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17155006 0.655 rs424978 chr7:107724747 C/G cg05962710 chr7:107745446 LAMB4 -0.19 -4.68 -0.39 7.52e-6 Pneumococcal bacteremia; TGCT cis rs17401966 0.838 rs35759975 chr1:10474430 A/T cg19773385 chr1:10388646 KIF1B -0.22 -5.17 -0.42 9.17e-7 Hepatocellular carcinoma; TGCT cis rs12477438 0.798 rs10198293 chr2:99602929 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs7267979 0.903 rs2474769 chr20:25248725 C/T cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs76473307 1.000 rs74395447 chr20:57413187 T/C cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs10431058 1.000 rs35005608 chr11:107478873 G/T cg18204760 chr11:107461044 ELMOD1;LOC643923 0.68 6.37 0.5 3.36e-9 Common traits (Other); TGCT cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg01448562 chr3:133502909 NA 0.35 7.16 0.54 6.23e-11 Iron status biomarkers; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg00024416 chr22:24240387 NA -0.24 -4.55 -0.38 1.28e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2996428 0.667 rs61768932 chr1:3765671 G/C cg17848003 chr1:3704513 LRRC47 0.19 5.21 0.42 7.56e-7 Red cell distribution width; TGCT cis rs7552404 0.765 rs1251078 chr1:76189488 C/G cg22875332 chr1:76189707 ACADM -0.82 -12.27 -0.74 3.78e-23 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10833905 0.715 rs7117292 chr11:23038771 G/A cg06387204 chr11:22647648 FANCF 0.52 4.77 0.39 5.01e-6 Sudden cardiac arrest; TGCT cis rs7772486 0.742 rs4896851 chr6:146278959 T/C cg05347473 chr6:146136440 FBXO30 -0.51 -4.75 -0.39 5.63e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9394841 0.667 rs71558769 chr6:41782107 T/C cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs611744 0.967 rs650401 chr8:109196854 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs1215050 0.874 rs17545594 chr4:98652689 A/G cg05340658 chr4:99064831 C4orf37 -0.44 -5.17 -0.42 9.1e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2070488 0.965 rs2366123 chr3:38493153 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.67 0.66 7.99e-17 Electrocardiographic conduction measures; TGCT cis rs1552244 0.572 rs58223482 chr3:10169746 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs6952808 0.500 rs3778996 chr7:2177190 G/A cg04267008 chr7:1944627 MAD1L1 -0.38 -4.86 -0.4 3.54e-6 Bipolar disorder and schizophrenia; TGCT cis rs6725041 0.547 rs59096325 chr2:213203853 C/T cg16329650 chr2:213403929 ERBB4 -0.67 -5.85 -0.47 4.03e-8 QT interval (ambient particulate matter interaction); TGCT cis rs9388451 0.626 rs1343116 chr6:126069702 C/A cg05901451 chr6:126070800 HEY2 -1.04 -13.0 -0.76 6.65e-25 Brugada syndrome; TGCT cis rs3858526 0.839 rs10466484 chr11:5943696 A/G cg05234568 chr11:5960015 NA -0.45 -4.46 -0.37 1.84e-5 DNA methylation (variation); TGCT cis rs2729354 1.000 rs2511983 chr11:57346874 A/G cg24343310 chr11:57249947 NA 0.28 4.8 0.4 4.5e-6 Blood protein levels; TGCT cis rs1843834 0.505 rs7585047 chr2:225373897 C/T cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs9952991 0.941 rs2847280 chr18:12779342 A/G cg23598886 chr18:12777645 NA 0.62 5.9 0.47 3.25e-8 Inflammatory skin disease; TGCT cis rs8077577 0.789 rs11078411 chr17:18088094 C/T cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs2180341 0.842 rs6569476 chr6:127553539 G/A cg27446573 chr6:127587934 RNF146 1.06 8.23 0.59 2.16e-13 Breast cancer; TGCT cis rs9796 0.621 rs537244 chr15:41469313 G/T cg18705301 chr15:41695430 NDUFAF1 0.52 7.17 0.54 5.94e-11 Menopause (age at onset); TGCT cis rs6681544 0.760 rs2182600 chr1:82396766 A/G cg04226724 chr1:82268649 LPHN2 0.48 4.93 0.41 2.54e-6 Metabolite levels (X-11787); TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg16325326 chr1:53192061 ZYG11B 0.54 6.09 0.48 1.32e-8 Monocyte count; TGCT cis rs651907 0.535 rs13094753 chr3:101525082 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.47 0.68 9.24e-19 Colorectal cancer; TGCT cis rs12477438 0.539 rs12999417 chr2:99865548 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -8.5 -0.61 4.95e-14 Chronic sinus infection; TGCT trans rs4650994 0.544 rs6682815 chr1:178501109 T/C cg05059571 chr16:84539110 KIAA1609 -0.55 -11.43 -0.72 4.08e-21 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6500602 0.727 rs4786516 chr16:4578641 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.95 0.47 2.54e-8 Schizophrenia; TGCT cis rs10174077 0.874 rs6750342 chr2:152485754 A/G cg19508488 chr2:152266495 RIF1 0.7 6.63 0.51 9.16e-10 Squamous cell lung carcinoma; TGCT trans rs1814175 0.817 rs80244685 chr11:49763292 C/A cg11707556 chr5:10655725 ANKRD33B -0.45 -11.14 -0.71 2.17e-20 Height; TGCT cis rs6714710 0.580 rs17489915 chr2:98420431 T/C cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs6964587 1.000 rs415 chr7:91580490 A/G cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs524281 1.000 rs565198 chr11:65913508 A/T cg00563793 chr11:65837595 PACS1 -0.52 -4.73 -0.39 6.01e-6 Electroencephalogram traits; TGCT cis rs13108904 0.521 rs4974609 chr4:1356924 A/C cg13395646 chr4:1353034 KIAA1530 0.49 7.42 0.55 1.64e-11 Obesity-related traits; TGCT cis rs1670533 1.000 rs62879260 chr4:1050850 T/C cg27284194 chr4:1044797 NA 0.68 5.87 0.47 3.76e-8 Recombination rate (females); TGCT cis rs7246657 0.638 rs7246461 chr19:38196581 C/G cg03611452 chr19:38183253 ZNF781 -0.58 -5.13 -0.42 1.08e-6 Coronary artery calcification; TGCT cis rs3741151 1.000 rs7122825 chr11:73061324 C/T cg17517138 chr11:73019481 ARHGEF17 0.93 4.66 0.39 7.9e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs4455778 0.536 rs10266289 chr7:48941456 C/T cg26309511 chr7:48887640 NA -0.44 -5.24 -0.43 6.67e-7 Lung cancer in never smokers; TGCT cis rs10782582 0.593 rs11578480 chr1:76208989 T/G cg03433033 chr1:76189801 ACADM -0.6 -6.63 -0.51 9.16e-10 Daytime sleep phenotypes; TGCT cis rs67072384 1.000 rs7120700 chr11:72444676 A/G cg03713592 chr11:72463424 ARAP1 -0.89 -4.6 -0.38 1.02e-5 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs7091068 0.532 rs559590 chr10:95398886 C/T cg20715218 chr10:95462985 C10orf4 -0.49 -6.0 -0.47 2.02e-8 Urinary tract infection frequency; TGCT cis rs769267 0.965 rs8101938 chr19:19390497 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs9807989 0.524 rs4851576 chr2:103028895 C/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.18e-7 Asthma; TGCT cis rs7666738 0.830 rs13125432 chr4:98961253 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs61990749 0.597 rs176946 chr14:78178439 C/T cg02301378 chr14:78227641 SNW1;C14orf178 0.61 4.61 0.38 1e-5 Fibroblast growth factor basic levels; TGCT cis rs10992471 0.651 rs13296623 chr9:95301627 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.25 -0.43 6.26e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs72634258 0.554 rs4562654 chr1:7934423 A/T cg26816564 chr1:7831052 VAMP3 0.65 4.98 0.41 2.11e-6 Inflammatory bowel disease; TGCT cis rs921968 0.541 rs526897 chr2:219433597 C/T cg02176678 chr2:219576539 TTLL4 0.45 6.63 0.51 9.33e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg22800045 chr5:56110881 MAP3K1 0.53 4.48 0.37 1.67e-5 Initial pursuit acceleration; TGCT cis rs12681287 0.517 rs34367154 chr8:87508749 A/T cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg20637647 chr7:64974828 NA 0.88 5.12 0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs1799949 1.000 rs4793231 chr17:41427469 A/G cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs6062788 0.504 rs8124644 chr20:61699728 C/T cg04845185 chr20:61696220 NA -0.31 -4.88 -0.4 3.21e-6 Body mass index; TGCT cis rs67478160 0.634 rs2368559 chr14:104230535 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.38 -0.5 3.18e-9 Schizophrenia; TGCT cis rs9549367 0.789 rs2287248 chr13:113889226 T/C cg18105134 chr13:113819100 PROZ -0.34 -5.49 -0.44 2.18e-7 Platelet distribution width; TGCT cis rs13392177 0.672 rs1877715 chr2:219052546 C/T cg00012203 chr2:219082015 ARPC2 0.72 7.48 0.56 1.16e-11 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg12310025 chr6:25882481 NA -0.67 -5.96 -0.47 2.41e-8 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT trans rs1814175 0.669 rs10839315 chr11:49654406 G/A cg03929089 chr4:120376271 NA -0.62 -7.33 -0.55 2.56e-11 Height; TGCT cis rs6504663 0.558 rs7627 chr17:48552154 G/C cg03168497 chr17:48586147 MYCBPAP 0.49 5.27 0.43 5.98e-7 Visceral fat; TGCT cis rs1670533 0.746 rs688008 chr4:1082829 T/C cg20887711 chr4:1340912 KIAA1530 0.68 5.33 0.43 4.53e-7 Recombination rate (females); TGCT cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10791323 0.569 rs2187450 chr11:133743792 A/G cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs10883723 1.000 rs10883723 chr10:104225832 T/C cg05855489 chr10:104503620 C10orf26 -0.53 -4.56 -0.38 1.19e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7954584 0.531 rs1154514 chr12:122374888 C/T cg21171335 chr12:122356390 WDR66 0.69 6.98 0.53 1.56e-10 Mean corpuscular volume; TGCT cis rs977747 1.000 rs7534271 chr1:47693981 C/G cg03885399 chr1:47691550 TAL1 0.39 4.55 0.38 1.25e-5 Body mass index; TGCT cis rs10794720 0.748 rs11250274 chr10:1171354 T/C cg08668510 chr10:1095578 IDI1 1.12 4.72 0.39 6.35e-6 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease; TGCT cis rs875971 1.000 rs2420591 chr7:65912381 T/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs7727544 0.735 rs272881 chr5:131669264 G/A cg24060327 chr5:131705240 SLC22A5 -0.56 -6.31 -0.49 4.43e-9 Blood metabolite levels; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg12419862 chr22:24373484 LOC391322 -0.75 -7.61 -0.56 5.89e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17076896 0.786 rs61956062 chr13:19928282 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs4478858 0.684 rs16865957 chr1:31753353 G/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs17376456 0.877 rs12716460 chr5:93416733 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.58 0.38 1.11e-5 Diabetic retinopathy; TGCT cis rs425277 1.000 rs427811 chr1:2075560 T/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.37 -4.7 -0.39 6.72e-6 Height; TGCT cis rs941408 1.000 rs2741990 chr19:2796644 C/T cg06609049 chr19:2785107 THOP1 0.8 7.95 0.58 9.66e-13 Total cholesterol levels; TGCT cis rs59197085 0.636 rs4731515 chr7:128450592 A/G cg00260937 chr7:128520193 KCP 0.47 4.86 0.4 3.49e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs9611565 0.765 rs132906 chr22:41799767 G/C cg03806693 chr22:41940476 POLR3H 0.92 10.04 0.67 9.93e-18 Vitiligo; TGCT cis rs11077998 0.967 rs4789782 chr17:80489323 G/T cg10255544 chr17:80519551 FOXK2 -0.24 -4.67 -0.39 7.86e-6 Reticulocyte fraction of red cells; TGCT cis rs10791323 0.575 rs4489760 chr11:133732265 A/T cg15485101 chr11:133734466 NA 0.37 5.0 0.41 1.94e-6 Childhood ear infection; TGCT cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs597539 0.652 rs482172 chr11:68668437 C/A cg06112835 chr11:68658793 MRPL21 0.47 8.3 0.6 1.48e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3741404 0.791 rs7102177 chr11:63909228 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.88 9.59 0.65 1.28e-16 Platelet count; TGCT cis rs2228479 0.850 rs11647174 chr16:89958538 G/A cg06558623 chr16:89946397 TCF25 0.57 6.52 0.51 1.62e-9 Skin colour saturation; TGCT cis rs6088580 0.608 rs2105109 chr20:32971932 A/G cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs35849525 0.633 rs62263602 chr3:50152491 C/T cg14019146 chr3:50243930 SLC38A3 -0.21 -4.58 -0.38 1.11e-5 Intelligence (multi-trait analysis); TGCT cis rs7843479 1.000 rs13276082 chr8:21823184 A/G cg17168535 chr8:21777572 XPO7 0.64 5.91 0.47 3.12e-8 Mean corpuscular volume; TGCT cis rs1799949 0.931 rs9912203 chr17:41445145 A/G cg10047753 chr17:41438598 NA -0.87 -8.58 -0.61 3.31e-14 Menopause (age at onset); TGCT cis rs7428 0.527 rs1061782 chr2:85546615 A/G cg03728395 chr2:85555865 TGOLN2 0.32 5.74 0.46 6.8e-8 Ear protrusion; TGCT cis rs881375 0.933 rs7021206 chr9:123684157 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.45 -5.02 -0.41 1.72e-6 Rheumatoid arthritis; TGCT cis rs9443189 0.570 rs569731 chr6:76357593 G/A cg01950844 chr6:76311363 SENP6 1.0 6.24 0.49 6.35e-9 Prostate cancer; TGCT cis rs7954584 0.616 rs10743186 chr12:122356436 C/T cg21016266 chr12:122356598 WDR66 0.43 5.65 0.45 1.03e-7 Mean corpuscular volume; TGCT cis rs9910055 0.529 rs190144 chr17:42164584 A/G cg13607699 chr17:42295918 UBTF -0.63 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT cis rs12048904 0.619 rs12239082 chr1:101330077 G/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.87 -8.56 -0.61 3.68e-14 Multiple sclerosis; TGCT cis rs72945132 0.638 rs11236127 chr11:70241536 G/C cg00319359 chr11:70116639 PPFIA1 1.0 7.12 0.54 7.76e-11 Coronary artery disease; TGCT cis rs2303745 0.589 rs1965717 chr19:17398559 C/T cg04248312 chr19:17393744 ANKLE1 -0.34 -5.57 -0.45 1.54e-7 Systemic lupus erythematosus; TGCT cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.28 -0.43 5.51e-7 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.597 rs7746618 chr6:146281367 T/C cg13319975 chr6:146136371 FBXO30 0.63 5.64 0.45 1.09e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10892173 0.545 rs115865940 chr11:117666711 C/T cg21014159 chr11:117668035 DSCAML1 0.61 6.05 0.48 1.61e-8 Myopia; TGCT cis rs8060598 0.745 rs8045009 chr16:50735941 C/T cg05261686 chr16:50743296 NOD2 0.23 4.5 0.37 1.56e-5 Leprosy; TGCT cis rs1891275 0.515 rs1080496 chr10:93444262 C/T cg07889827 chr10:93443413 NA 0.31 6.22 0.49 6.87e-9 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.791 rs7395713 chr11:49877887 A/G cg11707556 chr5:10655725 ANKRD33B -0.38 -7.42 -0.55 1.65e-11 Height; TGCT cis rs71435601 0.574 rs547179 chr2:21384662 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs3784262 0.679 rs8031578 chr15:58369145 T/C cg12031962 chr15:58353849 ALDH1A2 -0.41 -5.86 -0.47 3.82e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs8031584 0.678 rs798086 chr15:31129211 C/G cg14829155 chr15:31115871 NA 0.37 4.92 0.4 2.75e-6 Huntington's disease progression; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.65 0.39 8.4e-6 Prudent dietary pattern; TGCT cis rs7172809 0.897 rs74026931 chr15:77825474 A/C cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs748404 0.578 rs510108 chr15:43605439 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.46e-6 Lung cancer; TGCT trans rs324780 0.567 rs3103477 chr12:83908280 A/G cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.42e-10 Vertical cup-disc ratio; TGCT cis rs6088580 0.634 rs6119497 chr20:33012529 T/A cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs2730245 1.000 rs2252502 chr7:158738634 G/C cg11984989 chr7:158649758 WDR60 -0.97 -8.97 -0.63 3.94e-15 Height; TGCT cis rs2458413 0.521 rs2458427 chr8:105339594 G/T cg13045555 chr8:105342365 NA -0.41 -6.85 -0.52 3.05e-10 Paget's disease; TGCT cis rs751728 0.717 rs3763260 chr6:33774070 C/T cg00334056 chr6:33755658 LEMD2 -0.26 -4.75 -0.39 5.41e-6 Crohn's disease; TGCT cis rs1568889 1.000 rs16917689 chr11:28064466 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs4711336 1.000 rs764752 chr6:33658066 G/C cg14003231 chr6:33640908 ITPR3 0.28 4.5 0.37 1.54e-5 Height; TGCT trans rs208520 0.789 rs9351549 chr6:66871851 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.31 -0.68 2.29e-18 Exhaled nitric oxide output; TGCT cis rs2075371 1.000 rs2241336 chr7:133979578 A/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.36e-9 Mean platelet volume; TGCT cis rs2657888 0.930 rs7312441 chr12:56941146 C/A cg23932658 chr12:57637574 STAC3 -0.51 -4.73 -0.39 5.9e-6 Adiponectin levels; TGCT cis rs6906287 0.625 rs7764272 chr6:118692498 A/C cg21191810 chr6:118973309 C6orf204 0.28 4.68 0.39 7.38e-6 Electrocardiographic conduction measures; TGCT cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg20999797 chr1:1681921 NA 0.18 4.51 0.38 1.51e-5 Body mass index; TGCT trans rs1974653 0.672 rs9606252 chr22:20092996 A/G cg08822737 chr17:71088851 SLC39A11 0.88 7.33 0.55 2.61e-11 Schizophrenia; TGCT cis rs12579753 0.917 rs7972839 chr12:82178920 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.16 -0.48 9.4e-9 Resting heart rate; TGCT cis rs6964587 1.000 rs7811873 chr7:91751120 G/A cg17063962 chr7:91808500 NA 0.89 9.51 0.65 1.95e-16 Breast cancer; TGCT cis rs763014 0.932 rs2269560 chr16:682442 A/C cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.12e-6 Height; TGCT cis rs2242116 0.727 rs4683298 chr3:46966387 C/G cg27129171 chr3:47204927 SETD2 0.63 6.18 0.49 8.32e-9 Birth weight; TGCT cis rs12477438 0.501 rs2632284 chr2:99775865 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.32 0.85 4.52e-37 Chronic sinus infection; TGCT cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg03806693 chr22:41940476 POLR3H -1.04 -10.57 -0.69 5.2e-19 Vitiligo; TGCT cis rs6089829 0.816 rs6062397 chr20:61668268 A/G cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs2997447 0.894 rs55722280 chr1:26412684 T/C cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.16e-5 QRS complex (12-leadsum); TGCT trans rs1908814 0.516 rs13252854 chr8:11792978 T/A cg15556689 chr8:8085844 FLJ10661 0.77 7.37 0.55 2.13e-11 Neuroticism; TGCT cis rs9913156 0.670 rs9894225 chr17:4546559 A/G cg00122941 chr17:4613640 ARRB2 -0.83 -7.38 -0.55 2e-11 Lymphocyte counts; TGCT cis rs8013055 0.846 rs10139744 chr14:105974696 G/A cg23356831 chr14:105996513 TMEM121 0.37 5.62 0.45 1.19e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9985766 0.958 rs62339909 chr4:151009714 C/T cg05926478 chr4:151174724 DCLK2 -0.25 -4.91 -0.4 2.82e-6 Coronary artery disease;Myocardial infarction; TGCT trans rs17685 0.753 rs10952840 chr7:75772878 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs12134245 0.776 rs12125947 chr1:91990487 T/C cg02896835 chr1:92012615 NA -0.27 -4.62 -0.38 9.32e-6 Breast cancer; TGCT cis rs317689 0.613 rs315112 chr12:69785926 T/A cg14784868 chr12:69753453 YEATS4 0.63 5.64 0.45 1.09e-7 Response to diuretic therapy; TGCT cis rs8180040 1.000 rs553989 chr3:47400328 A/G cg27129171 chr3:47204927 SETD2 -0.71 -8.76 -0.62 1.21e-14 Colorectal cancer; TGCT cis rs1008375 0.931 rs6449326 chr4:17699790 G/T cg18681998 chr4:17616180 MED28 0.77 7.31 0.55 2.88e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.791 rs10856933 chr4:98958542 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11785400 1.000 rs754957 chr8:143746416 A/G cg10596483 chr8:143751796 JRK 0.55 5.82 0.46 4.69e-8 Schizophrenia; TGCT cis rs9916302 0.706 rs584377 chr17:37460128 G/A cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs916888 0.821 rs199514 chr17:44856881 G/A cg16520312 chr17:43971471 MAPT;LOC100128977 0.59 5.1 0.42 1.21e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6500602 0.627 rs934929 chr16:4587789 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 -0.39 -5.7 -0.46 8.2e-8 Schizophrenia; TGCT cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs7412746 0.611 rs2280627 chr1:150935872 A/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.7 0.39 6.76e-6 Melanoma; TGCT cis rs2594989 0.943 rs2606733 chr3:11412319 C/T cg00170343 chr3:11313890 ATG7 0.65 5.02 0.41 1.74e-6 Circulating chemerin levels; TGCT cis rs1046896 0.521 rs3848403 chr17:80693899 C/T cg00960700 chr17:80709150 TBCD 0.51 5.04 0.41 1.58e-6 Glycated hemoglobin levels; TGCT cis rs9486719 1.000 rs3798296 chr6:97052286 G/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs6964587 1.000 rs10263309 chr7:91645265 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs853679 0.517 rs9380059 chr6:28132358 A/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs2243480 1.000 rs160655 chr7:65533214 T/C cg07424592 chr7:64974309 NA 1.33 8.82 0.62 8.94e-15 Diabetic kidney disease; TGCT cis rs3806843 1.000 rs10038174 chr5:140210616 G/A cg19875535 chr5:140030758 IK 0.35 5.86 0.47 3.93e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs453301 0.682 rs2929308 chr8:9084121 T/A cg06636001 chr8:8085503 FLJ10661 -0.66 -6.04 -0.48 1.65e-8 Joint mobility (Beighton score); TGCT trans rs208520 0.674 rs207103 chr6:66795568 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs4566357 0.595 rs2272203 chr2:227914655 C/G cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs7824557 0.527 rs4631425 chr8:11239054 C/T cg21775007 chr8:11205619 TDH -0.68 -6.6 -0.51 1.08e-9 Retinal vascular caliber; TGCT cis rs1520333 0.915 rs7463761 chr8:79370919 G/A cg16589705 chr8:80226364 NA -0.32 -4.51 -0.38 1.48e-5 Multiple sclerosis; TGCT cis rs10782582 0.593 rs11589276 chr1:76105545 G/A cg03433033 chr1:76189801 ACADM -0.61 -7.24 -0.55 4.07e-11 Daytime sleep phenotypes; TGCT cis rs909002 0.800 rs3134718 chr1:32089839 C/T cg11573219 chr1:32083031 HCRTR1 -0.45 -5.86 -0.47 3.82e-8 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.520 rs11123766 chr2:99780915 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs11098499 1.000 rs58601355 chr4:120186367 T/C cg09307838 chr4:120376055 NA 0.52 4.69 0.39 6.97e-6 Corneal astigmatism; TGCT cis rs10791097 0.582 rs2282578 chr11:130735691 A/T cg05962950 chr11:130786565 SNX19 0.9 11.39 0.72 5.2e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs62103177 0.525 rs4799117 chr18:77756604 G/A cg20368463 chr18:77673604 PQLC1 -0.43 -4.46 -0.37 1.83e-5 Opioid sensitivity; TGCT cis rs67460515 0.892 rs34771618 chr3:161059795 A/C cg03342759 chr3:160939853 NMD3 -0.54 -5.9 -0.47 3.25e-8 Parkinson's disease; TGCT cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs9788682 0.747 rs2915695 chr15:78739471 T/C cg24631222 chr15:78858424 CHRNA5 -0.61 -4.55 -0.38 1.25e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7666738 0.830 rs6532724 chr4:99060993 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4919694 1.000 rs58700372 chr10:104800205 T/C cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs17376456 0.877 rs10055741 chr5:93297187 C/T cg25358565 chr5:93447407 FAM172A 0.98 8.56 0.61 3.63e-14 Diabetic retinopathy; TGCT cis rs2439831 1.000 rs2444032 chr15:43755346 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.6 0.45 1.33e-7 Lung cancer in ever smokers; TGCT cis rs6912958 0.559 rs242280 chr6:88048714 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.47 6.29 0.49 5.04e-9 Monocyte percentage of white cells; TGCT cis rs12681287 0.640 rs67123356 chr8:87453992 A/C cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT trans rs1974653 0.672 rs2008701 chr22:20104235 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.65 -0.57 4.76e-12 Schizophrenia; TGCT cis rs10114408 0.959 rs10992962 chr9:96657124 C/G cg13679303 chr9:96623674 NA -0.36 -4.65 -0.39 8.3e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs17384381 1.000 rs1608536 chr1:85885836 C/T cg16011679 chr1:85725395 C1orf52 0.78 6.1 0.48 1.27e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2456568 0.802 rs7115629 chr11:93635477 G/A cg16099599 chr11:93583650 C11orf90 -0.4 -4.98 -0.41 2.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6671200 0.607 rs6671408 chr1:95697091 T/C cg20701556 chr1:95698924 RWDD3 -0.52 -5.27 -0.43 5.76e-7 Stearic acid (18:0) levels; TGCT cis rs11578119 0.689 rs1591149 chr1:170386716 T/C cg09767346 chr1:170501363 GORAB -0.6 -4.97 -0.41 2.2e-6 Male-pattern baldness; TGCT cis rs7772486 0.754 rs6906258 chr6:146089356 A/G cg23711669 chr6:146136114 FBXO30 -0.92 -10.41 -0.68 1.3e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs208520 0.837 rs208509 chr6:66941706 A/G cg07460842 chr6:66804631 NA -0.91 -9.1 -0.63 1.87e-15 Exhaled nitric oxide output; TGCT cis rs7647973 0.961 rs7619016 chr3:49272589 C/T cg06212747 chr3:49208901 KLHDC8B 0.59 4.72 0.39 6.28e-6 Menarche (age at onset); TGCT cis rs10754283 0.901 rs10922684 chr1:90117934 T/C cg03145924 chr1:90228473 NA -0.4 -4.52 -0.38 1.4e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs617219 0.726 rs2364596 chr5:78434291 C/T cg23514016 chr5:78407564 BHMT 0.34 5.09 0.42 1.28e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4076764 0.846 rs10753616 chr1:163415855 G/T cg24596788 chr1:163392923 NA 0.16 4.69 0.39 7.08e-6 Motion sickness; TGCT cis rs7599312 0.534 rs10180824 chr2:213407975 G/A cg16329650 chr2:213403929 ERBB4 1.08 16.09 0.82 3.86e-32 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7772486 0.641 rs9390370 chr6:146357569 C/T cg13319975 chr6:146136371 FBXO30 -0.65 -6.11 -0.48 1.2e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs9517320 0.534 rs9554478 chr13:99187792 G/A cg20487152 chr13:99095054 FARP1 -0.24 -4.44 -0.37 1.93e-5 Longevity; TGCT cis rs7412746 0.658 rs3768015 chr1:150812954 C/T cg04414720 chr1:150670196 GOLPH3L 0.41 5.14 0.42 1.06e-6 Melanoma; TGCT cis rs185694 0.779 rs609919 chr13:30895904 C/G cg07600127 chr13:30881527 KATNAL1 -0.74 -6.11 -0.48 1.18e-8 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs12765878 1.000 rs3850671 chr10:105659387 T/C cg11005552 chr10:105648138 OBFC1 0.45 7.91 0.58 1.21e-12 Coronary artery disease; TGCT cis rs4642101 0.737 rs4299468 chr3:12825559 G/A cg05775895 chr3:12838266 CAND2 0.79 9.04 0.63 2.61e-15 QRS complex (12-leadsum); TGCT cis rs9905704 0.647 rs11652713 chr17:57079742 C/T cg05425664 chr17:57184151 TRIM37 -0.63 -5.54 -0.45 1.74e-7 Testicular germ cell tumor; TGCT cis rs1163251 0.837 rs660073 chr1:120245173 T/C cg19096424 chr1:120255104 PHGDH 0.6 5.93 0.47 2.76e-8 Blood metabolite levels; TGCT cis rs4819052 0.851 rs1056099 chr21:46678892 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.06 0.54 1.07e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT trans rs561341 0.739 rs9906455 chr17:30215669 G/A cg20587970 chr11:113659929 NA 0.65 8.95 0.63 4.33e-15 Hip circumference adjusted for BMI; TGCT cis rs10504229 0.639 rs2291764 chr8:58142943 A/C cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg11301795 chr4:187892539 NA -0.33 -4.82 -0.4 4.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9326248 0.581 rs7106437 chr11:116992076 T/C cg01368799 chr11:117014884 PAFAH1B2 0.61 5.58 0.45 1.43e-7 Blood protein levels; TGCT cis rs17221829 0.965 rs3871189 chr11:89451250 G/A cg02982614 chr11:89391479 FOLH1B -0.29 -5.09 -0.42 1.3e-6 Anxiety in major depressive disorder; TGCT cis rs514406 0.505 rs856721 chr1:53162156 C/A cg16325326 chr1:53192061 ZYG11B 0.85 11.54 0.72 2.24e-21 Monocyte count; TGCT cis rs17376456 1.000 rs9968691 chr5:93509756 C/G cg21475434 chr5:93447410 FAM172A 0.62 4.5 0.37 1.54e-5 Diabetic retinopathy; TGCT cis rs57590327 0.503 rs7618973 chr3:81619588 C/T cg07356753 chr3:81810745 GBE1 0.61 5.1 0.42 1.24e-6 Extraversion; TGCT cis rs4944092 0.960 rs10400322 chr11:75910913 C/T cg04588336 chr11:75916460 WNT11 0.43 6.08 0.48 1.35e-8 PR interval; TGCT cis rs801193 1.000 rs2659909 chr7:66160279 G/A cg18876405 chr7:65276391 NA 0.39 5.94 0.47 2.65e-8 Aortic root size; TGCT cis rs916888 0.773 rs169201 chr17:44790203 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.76 5.05 0.41 1.51e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs875971 1.000 rs1363055 chr7:65943275 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg06896619 chr17:61851486 DDX42;CCDC47 0.53 5.33 0.43 4.46e-7 Prudent dietary pattern; TGCT cis rs12477438 0.520 rs7604557 chr2:99747829 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.28 0.77 1.43e-25 Chronic sinus infection; TGCT cis rs10832169 0.967 rs7102483 chr11:14065883 A/G cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs8017423 0.935 rs8012303 chr14:90715829 G/A cg04374321 chr14:90722782 PSMC1 0.72 7.54 0.56 8.86e-12 Mortality in heart failure; TGCT cis rs7940866 0.801 rs2113928 chr11:130835975 A/G cg12179176 chr11:130786555 SNX19 0.64 6.05 0.48 1.57e-8 Schizophrenia; TGCT cis rs9311474 0.659 rs7638808 chr3:52572056 C/T cg10802521 chr3:52805072 NEK4 0.74 9.21 0.64 1.02e-15 Electroencephalogram traits; TGCT cis rs17270561 0.541 rs12192932 chr6:25911502 A/G cg17691542 chr6:26056736 HIST1H1C 0.89 6.28 0.49 5.19e-9 Iron status biomarkers; TGCT cis rs4455778 0.659 rs11185621 chr7:49027065 C/T cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.2 -0.42 7.9e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs478304 0.530 rs11568300 chr11:65425167 C/G cg27068330 chr11:65405492 SIPA1 -0.99 -10.62 -0.69 3.92e-19 Acne (severe); TGCT cis rs7819412 0.560 rs3021497 chr8:10996089 A/G cg21775007 chr8:11205619 TDH -0.51 -4.48 -0.37 1.67e-5 Triglycerides; TGCT cis rs597539 0.652 rs488363 chr11:68658298 C/G cg06112835 chr11:68658793 MRPL21 0.47 8.03 0.59 6.25e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs72781680 0.848 rs2339926 chr2:24045734 C/G cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT trans rs1005277 0.579 rs2474568 chr10:38383147 A/T cg17830980 chr10:43048298 ZNF37B -0.85 -10.57 -0.69 5.07e-19 Extrinsic epigenetic age acceleration; TGCT cis rs79349575 0.749 rs1057902 chr17:47005588 C/T cg26022315 chr17:47021804 SNF8 0.5 4.89 0.4 3.11e-6 Type 2 diabetes; TGCT cis rs12681287 0.640 rs7461413 chr8:87470978 C/G cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs2467099 0.504 rs2666005 chr17:73944596 T/G cg02678768 chr17:74002944 EVPL 0.28 4.82 0.4 4.14e-6 Systolic blood pressure; TGCT cis rs9807989 0.507 rs6543133 chr2:103040177 A/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs2228479 0.850 rs17233455 chr16:89816407 A/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs559928 0.606 rs76653616 chr11:63936139 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 4.61 0.38 9.89e-6 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs9993613 0.846 rs16848337 chr4:73493078 C/G cg15102770 chr4:73434591 ADAMTS3 0.52 4.87 0.4 3.28e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs231513 0.911 rs124720 chr17:41960141 A/G cg26893861 chr17:41843967 DUSP3 -0.76 -5.45 -0.44 2.62e-7 Cognitive function; TGCT cis rs2243480 1.000 rs35391607 chr7:65360829 G/A cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs9467773 0.595 rs13207371 chr6:26591074 G/A cg26531700 chr6:26746687 NA 0.61 5.75 0.46 6.7e-8 Intelligence (multi-trait analysis); TGCT cis rs4077468 1.000 rs4077469 chr1:205914885 C/T cg07157834 chr1:205819609 PM20D1 -0.31 -4.43 -0.37 2.01e-5 Cystic fibrosis-related diabetes; TGCT cis rs546131 0.600 rs502857 chr11:34854662 A/G cg06937548 chr11:34938143 PDHX;APIP 0.52 4.54 0.38 1.32e-5 Lung disease severity in cystic fibrosis; TGCT cis rs72781680 0.898 rs72786277 chr2:24062818 T/G cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs13256369 0.802 rs1060106 chr8:8561452 A/G cg18904891 chr8:8559673 CLDN23 0.57 5.27 0.43 5.87e-7 Obesity-related traits; TGCT cis rs6964587 0.967 rs6465353 chr7:91779971 G/T cg22709100 chr7:91322751 NA -0.28 -4.86 -0.4 3.53e-6 Breast cancer; TGCT cis rs4665809 1.000 rs11126364 chr2:26314515 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs9921222 0.565 rs10903014 chr16:377623 A/G cg00101154 chr16:420108 MRPL28 -0.57 -6.07 -0.48 1.43e-8 Bone mineral density (spine);Bone mineral density; TGCT cis rs425277 0.606 rs377283 chr1:2075570 T/C cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.36 -5.13 -0.42 1.1e-6 Height; TGCT cis rs7954584 0.531 rs1154514 chr12:122374888 C/T cg22168489 chr12:122356033 WDR66 0.22 4.76 0.39 5.26e-6 Mean corpuscular volume; TGCT cis rs11676348 0.783 rs13035513 chr2:218960680 C/T cg00012203 chr2:219082015 ARPC2 -0.53 -4.89 -0.4 3.04e-6 Ulcerative colitis; TGCT cis rs2303759 0.958 rs1465697 chr19:49837246 C/T cg22307029 chr19:49891270 CCDC155 0.56 5.28 0.43 5.57e-7 Multiple sclerosis; TGCT cis rs208520 0.526 rs1385219 chr6:66754476 C/T cg07460842 chr6:66804631 NA 1.03 13.88 0.78 5.09e-27 Exhaled nitric oxide output; TGCT cis rs7914558 0.869 rs10883842 chr10:104941589 C/T cg05855489 chr10:104503620 C10orf26 0.5 4.47 0.37 1.71e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7267979 1.000 rs6107033 chr20:25363591 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9357506 1.000 rs74869372 chr6:46314617 T/A cg21115430 chr6:46460003 NA -0.26 -5.06 -0.41 1.49e-6 Body mass index; TGCT cis rs2072499 1.000 rs2241108 chr1:156181007 C/G cg25208724 chr1:156163844 SLC25A44 1.11 15.91 0.82 9.79e-32 Testicular germ cell tumor; TGCT cis rs11190604 0.943 rs113791644 chr10:102324330 T/G cg23241863 chr10:102295624 HIF1AN 0.74 5.42 0.44 3.05e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs78487399 0.808 rs78191305 chr2:43673978 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.09 -0.42 1.3e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9467773 0.967 rs1056347 chr6:26527524 G/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs1997103 0.954 rs7811098 chr7:55413012 A/G cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs28595532 0.702 rs116320061 chr4:119384600 C/T cg11846333 chr4:119757529 SEC24D 0.7 4.59 0.38 1.08e-5 Cannabis dependence symptom count; TGCT cis rs639012 0.636 rs7110631 chr11:85856187 C/G cg07180834 chr11:85838833 NA -0.33 -4.91 -0.4 2.84e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6424115 1.000 rs58035855 chr1:24165248 G/C cg15997130 chr1:24165203 NA -0.9 -10.3 -0.68 2.37e-18 Immature fraction of reticulocytes; TGCT cis rs10489202 0.535 rs12736786 chr1:167988283 C/G cg24449463 chr1:168025552 DCAF6 -0.57 -6.67 -0.51 7.63e-10 Schizophrenia; TGCT cis rs10744422 0.843 rs3896870 chr12:123333611 T/C cg25930673 chr12:123319894 HIP1R -0.84 -4.87 -0.4 3.26e-6 Schizophrenia; TGCT cis rs11098499 0.954 rs878373 chr4:120237484 A/T cg09307838 chr4:120376055 NA 0.63 5.89 0.47 3.41e-8 Corneal astigmatism; TGCT cis rs782590 0.935 rs782568 chr2:55881538 T/C cg03859395 chr2:55845619 SMEK2 0.9 10.52 0.69 6.93e-19 Metabolic syndrome; TGCT cis rs9527 0.590 rs12414232 chr10:104914491 A/T cg15744005 chr10:104629667 AS3MT -0.41 -4.73 -0.39 6.06e-6 Arsenic metabolism; TGCT cis rs7552404 0.889 rs2211080 chr1:76243438 G/A cg03433033 chr1:76189801 ACADM 0.67 7.0 0.53 1.41e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12134133 1.000 rs2782842 chr1:207483576 C/T cg02152968 chr1:207494213 CD55 0.7 4.59 0.38 1.05e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7674212 0.541 rs2045746 chr4:104083578 A/C cg16532752 chr4:104119610 CENPE 0.52 4.81 0.4 4.37e-6 Type 2 diabetes; TGCT cis rs231513 0.954 rs231514 chr17:41964516 C/T cg26893861 chr17:41843967 DUSP3 -0.75 -5.3 -0.43 5.18e-7 Cognitive function; TGCT cis rs3087591 0.922 rs2905788 chr17:29480295 C/T cg24425628 chr17:29625626 OMG;NF1 0.46 7.23 0.54 4.3e-11 Hip circumference; TGCT cis rs1580019 1.000 rs1580019 chr7:32493169 A/T cg06627557 chr7:32535165 LSM5;AVL9 -0.73 -6.89 -0.53 2.52e-10 Cognitive ability; TGCT cis rs12477438 0.798 rs2045057 chr2:99684929 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs3733585 0.773 rs13107466 chr4:10019390 G/A cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11605924 0.934 rs7945689 chr11:45879006 C/T ch.11.939596F chr11:45881766 CRY2 -0.38 -4.67 -0.39 7.8e-6 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs4319547 0.956 rs9988963 chr12:122991478 C/G cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.1 -0.42 1.22e-6 Body mass index; TGCT cis rs10782582 0.593 rs11576534 chr1:76112751 C/T cg10523679 chr1:76189770 ACADM -0.66 -6.97 -0.53 1.69e-10 Daytime sleep phenotypes; TGCT cis rs17376456 0.877 rs17083460 chr5:93462354 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs202629 1 rs202629 chr22:41849975 C/T cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Cannabis dependence symptom count; TGCT cis rs7714584 0.590 rs115823027 chr5:150265951 G/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs12780845 0.540 rs2356829 chr10:17223625 C/T cg01003015 chr10:17271136 VIM 0.58 4.61 0.38 9.67e-6 Homocysteine levels; TGCT cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg09323728 chr8:95962352 TP53INP1 -0.49 -6.32 -0.49 4.22e-9 Type 2 diabetes; TGCT cis rs11122272 0.735 rs2486734 chr1:231531392 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -6.35 -0.5 3.66e-9 Hemoglobin concentration; TGCT cis rs12777 0.571 rs6868463 chr5:131856053 T/G cg16609957 chr5:132161867 SHROOM1 -0.35 -4.68 -0.39 7.43e-6 Fibrinogen levels; TGCT cis rs6840360 0.615 rs12647462 chr4:152607278 C/T cg22705602 chr4:152727874 NA -0.32 -5.44 -0.44 2.76e-7 Intelligence (multi-trait analysis); TGCT cis rs9814567 1.000 rs9884031 chr3:134256500 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.49 -0.65 2.15e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs8073060 0.963 rs4795082 chr17:33873501 C/T cg19694781 chr19:47549865 TMEM160 0.42 7.77 0.57 2.52e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2997447 0.761 rs61776586 chr1:26438933 T/C cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs60843830 0.661 rs62116682 chr2:104618 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.62 5.52 0.44 1.92e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs250677 0.687 rs36046 chr5:148441257 A/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs2456568 0.803 rs10831138 chr11:93640468 T/C cg16099599 chr11:93583650 C11orf90 -0.39 -4.78 -0.39 4.97e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs1814175 0.591 rs11040589 chr11:49862449 A/G cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs9911578 1.000 rs6503866 chr17:56619581 C/T cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs939658 0.805 rs36068099 chr15:79438598 G/C cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs9443645 0.869 rs9361467 chr6:79621098 A/G cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs1775715 0.677 rs2808074 chr10:32179184 A/C cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs3796352 0.764 rs34872575 chr3:52986277 G/A cg15956490 chr3:53032818 SFMBT1 0.61 6.11 0.48 1.17e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs72781680 0.898 rs113522526 chr2:24018476 C/T cg08917208 chr2:24149416 ATAD2B 0.81 4.99 0.41 2.01e-6 Lymphocyte counts; TGCT cis rs9807989 0.507 rs2058659 chr2:103054556 A/G cg03938978 chr2:103052716 IL18RAP -0.25 -5.06 -0.41 1.47e-6 Asthma; TGCT cis rs12497850 0.897 rs7432989 chr3:49105136 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.51 0.44 2e-7 Parkinson's disease; TGCT cis rs4563143 0.514 rs73029079 chr19:29294903 A/G cg04546413 chr19:29218101 NA 0.73 5.38 0.43 3.65e-7 Methadone dose in opioid dependence; TGCT cis rs40363 0.729 rs6501176 chr16:3522197 A/G cg05754148 chr16:3507555 NAT15 -0.44 -5.57 -0.45 1.54e-7 Tuberculosis; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs4294134 0.608 rs13237671 chr7:135244604 T/C cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs45509595 0.841 rs370155 chr6:27782031 T/G cg10876282 chr6:28092338 ZSCAN16 0.78 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs17401966 0.931 rs3748579 chr1:10420937 C/T cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs17152411 0.895 rs61872121 chr10:126586795 T/C cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs7829975 0.774 rs11775523 chr8:8679176 A/G cg15556689 chr8:8085844 FLJ10661 0.69 6.17 0.48 8.84e-9 Mood instability; TGCT cis rs4851254 0.660 rs13430705 chr2:100690616 G/A cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs1532993 0.518 rs1911790 chr4:98586222 T/C cg05340658 chr4:99064831 C4orf37 -0.4 -4.76 -0.39 5.31e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs3026101 0.624 rs7426 chr17:5288983 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.5 4.89 0.4 3.11e-6 Body mass index; TGCT cis rs362272 0.524 rs7435601 chr4:3369645 A/G cg18352616 chr4:3374830 RGS12 0.25 5.12 0.42 1.15e-6 Serum sulfate level; TGCT cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg05890377 chr2:74357713 NA 0.53 7.11 0.54 8.05e-11 Gestational age at birth (maternal effect); TGCT cis rs360798 0.512 rs12989754 chr2:63020970 A/G cg17519650 chr2:63277830 OTX1 -0.6 -5.23 -0.43 7.02e-7 Coronary artery disease; TGCT cis rs12681287 0.547 rs9942792 chr8:87509046 C/T cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs28735056 0.904 rs11520415 chr18:77620620 C/T cg20368463 chr18:77673604 PQLC1 0.38 4.6 0.38 1.04e-5 Schizophrenia; TGCT cis rs651907 0.535 rs12633089 chr3:101528763 C/T cg12386194 chr3:101231763 SENP7 0.47 4.7 0.39 6.87e-6 Colorectal cancer; TGCT cis rs2243480 1.000 rs160639 chr7:65579987 C/G cg07424592 chr7:64974309 NA 1.22 7.36 0.55 2.2e-11 Diabetic kidney disease; TGCT cis rs950027 0.620 rs1145080 chr15:45681338 C/T cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs55883249 1.000 rs10495573 chr2:9712160 T/G cg23886495 chr2:9695866 ADAM17 0.82 4.8 0.4 4.47e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs6671200 0.748 rs79375907 chr1:95539561 C/T cg03123541 chr1:95699097 RWDD3 0.65 4.49 0.37 1.6e-5 Stearic acid (18:0) levels; TGCT cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg26531700 chr6:26746687 NA 0.5 4.65 0.39 8.29e-6 Intelligence (multi-trait analysis); TGCT cis rs9796 0.649 rs8035828 chr15:41467287 T/A cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.3 -0.55 3.07e-11 Menopause (age at onset); TGCT cis rs908922 0.676 rs569032 chr1:152508615 C/T cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs601339 1.000 rs4759361 chr12:123178280 T/A cg11919336 chr12:123188078 GPR109A 0.64 7.86 0.58 1.61e-12 Adiponectin levels; TGCT cis rs875971 0.522 rs1968127 chr7:66056803 C/T cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs7192750 0.562 rs4788573 chr16:71921946 A/C cg06353428 chr16:71660113 MARVELD3 0.82 7.26 0.55 3.82e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs59104589 0.920 rs59916403 chr2:242370751 G/T cg21155796 chr2:242212141 HDLBP 0.58 4.98 0.41 2.06e-6 Fibrinogen levels; TGCT cis rs597539 0.652 rs686390 chr11:68656077 T/C cg06112835 chr11:68658793 MRPL21 0.47 8.14 0.59 3.57e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6951245 1.000 rs75488469 chr7:1102122 A/G cg03188948 chr7:1209495 NA 0.68 5.72 0.46 7.53e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2880765 0.835 rs4842887 chr15:86035810 T/C cg13263323 chr15:86062960 AKAP13 -0.22 -4.84 -0.4 3.84e-6 Coronary artery disease; TGCT cis rs7267979 0.753 rs400357 chr20:25479058 A/G cg16686733 chr20:25566563 NINL 0.52 4.93 0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4808199 0.895 rs10403731 chr19:19469296 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.71 5.56 0.45 1.59e-7 Nonalcoholic fatty liver disease; TGCT cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg03609598 chr5:56110824 MAP3K1 -0.56 -4.57 -0.38 1.14e-5 Initial pursuit acceleration; TGCT cis rs77633900 0.614 rs2585730 chr15:76989344 A/G cg21673338 chr15:77095150 SCAPER -0.51 -4.89 -0.4 3.08e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs1008375 1.000 rs4698635 chr4:17630242 C/A cg10189774 chr4:17578691 LAP3 0.59 5.13 0.42 1.06e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.921 rs4822021 chr22:41726053 G/A cg03806693 chr22:41940476 POLR3H -0.97 -10.25 -0.68 3.06e-18 Vitiligo; TGCT cis rs910316 0.737 rs175048 chr14:75479894 A/T cg11812906 chr14:75593930 NEK9 -0.56 -5.28 -0.43 5.48e-7 Height; TGCT cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg17554472 chr22:41940697 POLR3H 0.48 5.08 0.42 1.34e-6 Vitiligo; TGCT trans rs66573146 1.000 rs55833486 chr4:6978729 C/A cg07817883 chr1:32538562 TMEM39B 1.42 7.53 0.56 8.92e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs12791968 1.000 rs1552301 chr11:45002551 A/G cg11846598 chr11:44996168 LOC221122 -0.36 -6.79 -0.52 4.04e-10 Inhibitory control; TGCT cis rs4665809 1.000 rs1470097 chr2:26312840 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.04 -0.48 1.7e-8 Gut microbiome composition (summer); TGCT cis rs735396 1.000 rs1169311 chr12:121440731 C/T cg02403541 chr12:121454288 C12orf43 0.66 6.27 0.49 5.35e-9 N-glycan levels; TGCT cis rs9486719 1.000 rs2499804 chr6:96861216 A/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7647973 1.000 rs3870341 chr3:49584745 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.85 -0.4 3.57e-6 Menarche (age at onset); TGCT cis rs7666738 0.830 rs1813972 chr4:98886828 C/A cg17366294 chr4:99064904 C4orf37 0.68 6.87 0.53 2.72e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs80282103 0.618 rs10794720 chr10:1156165 A/G cg08668510 chr10:1095578 IDI1 -0.92 -5.0 -0.41 1.88e-6 Glomerular filtration rate (creatinine); TGCT cis rs1580019 0.885 rs4580942 chr7:32496435 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.8 7.36 0.55 2.19e-11 Cognitive ability; TGCT cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs769267 0.931 rs2965197 chr19:19470910 C/T cg03709012 chr19:19516395 GATAD2A -0.69 -5.76 -0.46 6.23e-8 Tonsillectomy; TGCT cis rs453301 0.658 rs12114954 chr8:8904862 T/G cg06636001 chr8:8085503 FLJ10661 -0.69 -5.59 -0.45 1.37e-7 Joint mobility (Beighton score); TGCT cis rs4072705 0.967 rs4838209 chr9:127528842 C/T cg13476313 chr9:127244764 NR5A1 0.28 4.57 0.38 1.18e-5 Menarche (age at onset); TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.05 0.41 1.54e-6 Prudent dietary pattern; TGCT cis rs7264396 0.561 rs6060753 chr20:34598430 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -4.9 -0.4 2.97e-6 Total cholesterol levels; TGCT cis rs7666738 0.830 rs13145011 chr4:98993410 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12134245 0.776 rs6688261 chr1:91987034 C/T cg02896835 chr1:92012615 NA -0.26 -4.68 -0.39 7.37e-6 Breast cancer; TGCT cis rs4689592 0.503 rs66885632 chr4:7053738 T/C cg02503808 chr4:7069936 GRPEL1 -0.92 -7.34 -0.55 2.4e-11 Monocyte percentage of white cells; TGCT cis rs3862260 0.967 rs3862261 chr1:120160822 G/A cg16322792 chr1:120165303 ZNF697 0.27 5.71 0.46 7.73e-8 Systemic lupus erythematosus; TGCT cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg05368731 chr17:41323189 NBR1 1.15 13.28 0.77 1.44e-25 Menopause (age at onset); TGCT cis rs9443645 0.901 rs9352669 chr6:79584141 T/G cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs748404 0.631 rs2412781 chr15:43667900 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.46 -4.72 -0.39 6.3e-6 Lung cancer; TGCT cis rs17102423 0.755 rs11625045 chr14:65549089 C/T cg11161011 chr14:65562177 MAX -0.55 -7.77 -0.57 2.5e-12 Obesity-related traits; TGCT cis rs155076 1.000 rs658244 chr13:21850976 T/C cg14456004 chr13:21872349 NA -1.34 -11.21 -0.71 1.42e-20 White matter hyperintensity burden; TGCT trans rs6951245 0.554 rs11544331 chr7:1131411 C/T cg13565492 chr6:43139072 SRF -0.82 -7.72 -0.57 3.43e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs10876993 0.855 rs1689585 chr12:58080140 A/G cg15848620 chr12:58087721 OS9 0.7 5.81 0.46 4.92e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs11030122 0.660 rs10835250 chr11:3911198 G/T cg18678763 chr11:4115507 RRM1 -0.35 -4.45 -0.37 1.85e-5 Mean platelet volume;Platelet distribution width; TGCT trans rs9929218 0.551 rs3785133 chr16:68728611 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.59 7.67 0.57 4.25e-12 Colorectal cancer; TGCT cis rs2404602 0.716 rs8039545 chr15:76707247 A/G cg22467129 chr15:76604101 ETFA -0.59 -7.13 -0.54 7.33e-11 Blood metabolite levels; TGCT cis rs8051431 0.840 rs4788595 chr16:72025759 A/C cg06353428 chr16:71660113 MARVELD3 0.61 5.06 0.41 1.47e-6 LDL cholesterol levels; TGCT cis rs933688 0.938 rs7720235 chr5:90659329 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 1.03 9.27 0.64 7.28e-16 Smoking behavior; TGCT cis rs3617 0.573 rs9880978 chr3:52923251 C/G cg11645453 chr3:52864694 ITIH4 0.29 5.46 0.44 2.49e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4319547 0.695 rs7301515 chr12:122949673 T/C cg23029597 chr12:123009494 RSRC2 -0.3 -4.9 -0.4 2.88e-6 Body mass index; TGCT cis rs782590 0.934 rs62165184 chr2:55788253 G/C cg18811423 chr2:55921094 PNPT1 0.67 7.1 0.54 8.63e-11 Metabolic syndrome; TGCT cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg06634786 chr22:41940651 POLR3H -0.89 -8.44 -0.6 6.85e-14 Vitiligo; TGCT cis rs4819052 0.851 rs2838855 chr21:46680566 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.58 -4.61 -0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg27588902 chr6:42928151 GNMT -0.5 -5.97 -0.47 2.37e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6089829 0.962 rs9680064 chr20:61666168 G/A cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.51 5.5 0.44 2.06e-7 Lymphocyte counts; TGCT cis rs854765 0.624 rs12450799 chr17:17730201 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.6 -5.62 -0.45 1.19e-7 Total body bone mineral density; TGCT cis rs10509586 0.826 rs77506020 chr10:91898943 T/C cg25278353 chr10:91717815 NA 0.49 4.67 0.39 7.77e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs797680 0.856 rs1535699 chr1:93804952 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.07 -0.41 1.4e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7727544 0.716 rs72793278 chr5:131561372 C/A cg21474247 chr5:131268130 NA 0.32 4.54 0.38 1.32e-5 Blood metabolite levels; TGCT cis rs425277 0.606 rs262653 chr1:2090095 T/G cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.46 -0.37 1.81e-5 Height; TGCT cis rs35146811 0.700 rs2950520 chr7:99827148 T/C cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.78 -0.39 4.88e-6 Coronary artery disease; TGCT cis rs6831352 0.918 rs34071486 chr4:100051087 A/G cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.52 5.52 0.44 1.92e-7 Lymphocyte counts; TGCT cis rs1406084 0.636 rs7420387 chr2:154718142 C/T cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs2832191 0.716 rs7509628 chr21:30454252 C/T cg24692254 chr21:30365293 RNF160 0.98 11.36 0.71 6.16e-21 Dental caries; TGCT trans rs10506458 0.834 rs12426860 chr12:63387948 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.54 -0.56 8.62e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs35934224 0.783 rs56291622 chr22:19858734 C/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.22 -0.42 7.16e-7 Glaucoma (primary open-angle); TGCT cis rs6543140 0.929 rs6742530 chr2:103082280 G/A cg09003973 chr2:102972529 NA 0.55 4.56 0.38 1.2e-5 Blood protein levels; TGCT cis rs4711350 0.765 rs2182658 chr6:33748831 G/T cg13859433 chr6:33739653 LEMD2 0.32 4.82 0.4 4.08e-6 Schizophrenia; TGCT cis rs9611565 0.503 rs5996062 chr22:42167464 C/G cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs9650657 0.535 rs7011756 chr8:11019578 C/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.68 -0.39 7.54e-6 Neuroticism; TGCT cis rs2180341 1.000 rs9321073 chr6:127609691 C/T cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs9926296 0.712 rs2434872 chr16:89716915 C/G cg03388025 chr16:89894329 SPIRE2 -0.35 -5.05 -0.41 1.53e-6 Vitiligo; TGCT trans rs62103177 0.759 rs9956512 chr18:77607517 G/A cg05926928 chr17:57297772 GDPD1 1.22 11.62 0.72 1.41e-21 Opioid sensitivity; TGCT cis rs911555 0.504 rs4444269 chr14:104072724 G/C cg26031613 chr14:104095156 KLC1 0.61 5.6 0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs12210905 1.000 rs12196084 chr6:27198204 A/C cg08851530 chr6:28072375 NA 0.98 4.79 0.4 4.57e-6 Hip circumference adjusted for BMI; TGCT cis rs7607369 0.527 rs72966038 chr2:219656190 G/A cg02176678 chr2:219576539 TTLL4 -0.47 -6.01 -0.47 1.96e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs13108904 0.935 rs2293633 chr4:1291640 T/C cg13395646 chr4:1353034 KIAA1530 -0.4 -4.95 -0.41 2.4e-6 Obesity-related traits; TGCT cis rs11696501 0.694 rs4812943 chr20:44260966 G/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.58 -0.38 1.14e-5 Brain structure; TGCT cis rs7949030 0.765 rs11553576 chr11:62378801 T/C cg11742103 chr11:62369870 EML3;MTA2 0.62 9.17 0.64 1.27e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12615966 0.932 rs17030324 chr2:105403251 A/C cg16465502 chr2:105461796 NA 0.81 5.21 0.42 7.61e-7 Pancreatic cancer; TGCT cis rs2242116 0.761 rs6780601 chr3:46965856 A/G cg23352942 chr3:46931381 PTH1R -0.32 -4.53 -0.38 1.36e-5 Birth weight; TGCT cis rs3791556 0.898 rs3828222 chr2:240109568 A/G cg03281426 chr2:240109471 HDAC4 -0.28 -4.62 -0.38 9.66e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7617773 0.780 rs7653152 chr3:48362097 G/C cg11946769 chr3:48343235 NME6 0.82 7.11 0.54 8.07e-11 Coronary artery disease; TGCT cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs9329221 0.772 rs7824675 chr8:10243418 G/T cg27411982 chr8:10470053 RP1L1 -0.21 -4.83 -0.4 3.98e-6 Neuroticism; TGCT cis rs9300255 0.722 rs10846515 chr12:123801672 T/G cg00376283 chr12:123451042 ABCB9 0.65 4.57 0.38 1.17e-5 Neutrophil percentage of white cells; TGCT cis rs4665630 0.522 rs2712054 chr2:23956123 C/T cg08063864 chr2:24346004 PFN4;LOC375190 1.21 6.41 0.5 2.81e-9 Hypertension; TGCT cis rs4319547 0.698 rs10744217 chr12:122942070 A/G cg05707623 chr12:122985044 ZCCHC8 -0.61 -4.94 -0.41 2.43e-6 Body mass index; TGCT cis rs6121246 0.909 rs1994249 chr20:30287593 C/T cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs2463822 0.858 rs2513037 chr11:62084822 A/T cg06239285 chr11:62104954 ASRGL1 -0.91 -6.55 -0.51 1.36e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9296092 0.560 rs3846854 chr6:33528466 T/C cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg26119090 chr2:26468346 HADHA;HADHB -0.91 -6.69 -0.52 6.82e-10 Gut microbiome composition (summer); TGCT cis rs2153535 0.601 rs2143353 chr6:8530111 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs941408 1.000 rs1736179 chr19:2795516 T/A cg06609049 chr19:2785107 THOP1 0.79 7.79 0.57 2.36e-12 Total cholesterol levels; TGCT cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs6921919 0.583 rs6899603 chr6:28381305 A/G cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7618915 0.501 rs2289247 chr3:52727257 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.87 0.47 3.65e-8 Bipolar disorder; TGCT cis rs778371 0.697 rs4973564 chr2:233718440 A/G cg08000102 chr2:233561755 GIGYF2 -0.72 -8.51 -0.61 4.67e-14 Schizophrenia; TGCT cis rs6565180 0.889 rs8051096 chr16:30347731 A/G cg17640201 chr16:30407289 ZNF48 -0.87 -8.77 -0.62 1.15e-14 Tonsillectomy; TGCT cis rs3782455 0.590 rs16943539 chr12:114404337 T/G cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7267979 0.966 rs2261784 chr20:25262396 G/C cg03522245 chr20:25566470 NINL 0.62 6.61 0.51 1.04e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1903068 0.785 rs12331538 chr4:55998086 A/C cg16572876 chr4:56024045 NA 0.44 4.94 0.41 2.47e-6 Endometriosis; TGCT cis rs9611519 0.780 rs1983631 chr22:41644074 C/T cg13695892 chr22:41940480 POLR3H -0.59 -5.4 -0.44 3.26e-7 Neuroticism; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg17178900 chr1:205818956 PM20D1 0.59 7.49 0.56 1.14e-11 Menarche (age at onset); TGCT cis rs5750830 0.546 rs4821891 chr22:39785381 C/T cg05872129 chr22:39784769 NA -1.02 -11.72 -0.73 8.03e-22 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.546 rs62320963 chr4:98839297 A/G cg18180107 chr4:99064573 C4orf37 0.55 4.76 0.39 5.33e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4294134 0.608 rs11767351 chr7:135243837 A/G cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs9640161 0.658 rs60467296 chr7:150015471 G/A cg10018233 chr7:150070692 REPIN1 0.32 4.46 0.37 1.84e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs6920965 0.507 rs9401853 chr6:126215197 A/T cg05901451 chr6:126070800 HEY2 -0.66 -6.56 -0.51 1.3e-9 High light scatter reticulocyte count; TGCT cis rs8020441 1.000 rs68157165 chr14:51169220 A/G cg04730355 chr14:51134070 SAV1 0.73 6.02 0.48 1.84e-8 Cognitive performance; TGCT cis rs1215050 0.740 rs783924 chr4:98969234 C/T cg17366294 chr4:99064904 C4orf37 -0.55 -5.8 -0.46 5.23e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1005277 0.579 rs2474568 chr10:38383147 A/T cg25427524 chr10:38739819 LOC399744 -0.39 -7.84 -0.58 1.74e-12 Extrinsic epigenetic age acceleration; TGCT cis rs8072100 0.790 rs1962307 chr17:45707871 A/G cg08085267 chr17:45401833 C17orf57 -0.46 -4.96 -0.41 2.26e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs3026101 0.624 rs1806255 chr17:5314263 G/C cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs17030434 0.906 rs5020754 chr4:154670444 T/C cg14289246 chr4:154710475 SFRP2 -0.88 -7.18 -0.54 5.68e-11 Electrocardiographic conduction measures; TGCT cis rs9914544 0.545 rs12942794 chr17:18767217 A/C cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg02953382 chr22:24373134 LOC391322 -0.72 -6.82 -0.52 3.55e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7296418 0.961 rs4148863 chr12:123569375 A/G cg00376283 chr12:123451042 ABCB9 0.82 7.46 0.56 1.33e-11 Platelet count; TGCT cis rs3816788 0.774 rs11784816 chr8:21773500 C/T cg17168535 chr8:21777572 XPO7 -0.78 -7.41 -0.55 1.71e-11 Lung cancer in ever smokers; TGCT cis rs4665809 0.617 rs930263 chr2:26402594 G/C cg04944784 chr2:26401820 FAM59B -0.76 -6.32 -0.49 4.35e-9 Gut microbiome composition (summer); TGCT cis rs514406 0.621 rs881198 chr1:53196440 C/T cg01802117 chr1:53393560 SCP2 0.44 5.11 0.42 1.18e-6 Monocyte count; TGCT cis rs2204008 0.502 rs2387275 chr12:38142836 G/A cg26384229 chr12:38710491 ALG10B 0.92 8.1 0.59 4.38e-13 Bladder cancer; TGCT cis rs8103278 0.507 rs4802275 chr19:46260375 C/T cg11657440 chr19:46296263 DMWD 0.75 7.86 0.58 1.62e-12 Coronary artery disease; TGCT cis rs111803315 1.000 rs111237243 chr14:59991030 G/T cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs611744 0.647 rs689275 chr8:109241822 T/C cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.44e-11 Dupuytren's disease; TGCT cis rs8017423 0.967 rs1005788 chr14:90692747 C/T cg04374321 chr14:90722782 PSMC1 0.77 8.03 0.58 6.42e-13 Mortality in heart failure; TGCT cis rs10197940 0.578 rs2432946 chr2:152306897 G/T cg06191203 chr2:152266755 RIF1 0.57 4.74 0.39 5.78e-6 Lung cancer; TGCT cis rs2073300 1.000 rs34449811 chr20:23443771 T/C cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT trans rs7698623 0.850 rs6532019 chr4:88768672 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.62 -0.51 9.94e-10 Cardiovascular disease risk factors; TGCT cis rs7772486 0.875 rs10457792 chr6:146412415 T/C cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1420338 0.967 rs10272282 chr7:34172073 C/T cg01275685 chr7:34179230 BMPER -0.28 -5.08 -0.41 1.36e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs3796352 0.881 rs35384050 chr3:53008769 G/T cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs611744 0.967 rs684904 chr8:109199417 G/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg11965913 chr1:205819406 PM20D1 0.46 6.32 0.49 4.26e-9 Monocyte percentage of white cells; TGCT cis rs8017423 0.967 rs11626011 chr14:90693572 A/G cg04374321 chr14:90722782 PSMC1 0.76 7.83 0.58 1.9e-12 Mortality in heart failure; TGCT trans rs561341 0.700 rs2074101 chr17:30228656 G/A cg20587970 chr11:113659929 NA -0.6 -9.12 -0.63 1.65e-15 Hip circumference adjusted for BMI; TGCT cis rs28595532 0.920 rs114037572 chr4:119735609 T/G cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7937682 0.883 rs12804962 chr11:111442683 A/T cg09085632 chr11:111637200 PPP2R1B 1.0 9.68 0.66 7.65e-17 Primary sclerosing cholangitis; TGCT cis rs7216064 1.000 rs1976053 chr17:65833002 C/G cg12091567 chr17:66097778 LOC651250 -0.84 -6.75 -0.52 5.15e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7590720 1.000 rs1991533 chr2:216908910 T/C cg12620499 chr2:216877984 MREG 0.87 8.73 0.62 1.48e-14 Alcohol dependence; TGCT cis rs7412746 0.611 rs3768018 chr1:150723747 T/C cg09365446 chr1:150670422 GOLPH3L 0.32 4.58 0.38 1.1e-5 Melanoma; TGCT cis rs2230307 0.536 rs580611 chr1:100622925 G/A cg24955406 chr1:100503596 HIAT1 -0.74 -5.01 -0.41 1.8e-6 Carotid intima media thickness; TGCT cis rs1670533 0.932 rs4690347 chr4:1057328 A/G cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs9560113 0.806 rs9560112 chr13:112183320 A/G cg14154082 chr13:112174009 NA 0.36 4.8 0.4 4.52e-6 Menarche (age at onset); TGCT cis rs79387448 0.745 rs6709719 chr2:103144953 G/A cg09003973 chr2:102972529 NA 0.97 6.32 0.49 4.33e-9 Gut microbiota (bacterial taxa); TGCT cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs12360000 0.770 rs12573442 chr10:1910626 T/C cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs9650657 0.683 rs7830431 chr8:10700317 A/G cg27411982 chr8:10470053 RP1L1 -0.22 -4.67 -0.39 7.63e-6 Neuroticism; TGCT cis rs1008375 1.000 rs1860597 chr4:17657650 C/T cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg12310025 chr6:25882481 NA -0.53 -5.45 -0.44 2.58e-7 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs7208859 0.673 rs1347359 chr17:28914529 T/C cg19761014 chr17:28927070 LRRC37B2 0.54 4.67 0.39 7.61e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4689592 0.503 rs59640165 chr4:7051661 G/A cg02503808 chr4:7069936 GRPEL1 -0.94 -7.49 -0.56 1.14e-11 Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs7696686 chr4:98938445 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7208859 0.614 rs28758251 chr17:29223312 A/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs295140 0.564 rs296790 chr2:201232862 C/G cg04283868 chr2:201171347 SPATS2L -0.54 -5.22 -0.42 7.46e-7 QT interval; TGCT cis rs801193 1.000 rs2659912 chr7:66157999 G/C cg00343986 chr7:65444356 GUSB 0.23 5.02 0.41 1.79e-6 Aortic root size; TGCT cis rs975752 0.867 rs11190443 chr10:102023738 C/T cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs514406 0.861 rs562182 chr1:53270010 C/T cg25767906 chr1:53392781 SCP2 -0.51 -5.77 -0.46 6.07e-8 Monocyte count; TGCT cis rs7666738 1.000 rs13124102 chr4:98990696 G/A cg17366294 chr4:99064904 C4orf37 0.69 6.39 0.5 3.1e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2677744 0.688 rs2239293 chr15:91450350 G/A cg23684204 chr15:91497937 RCCD1 0.34 4.84 0.4 3.74e-6 Attention deficit hyperactivity disorder; TGCT cis rs7586879 0.765 rs11683429 chr2:25120733 T/A cg01884057 chr2:25150051 NA 0.27 4.81 0.4 4.36e-6 Body mass index; TGCT cis rs3806843 1.000 rs6870764 chr5:140171790 C/T cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9291683 0.588 rs35099040 chr4:10018839 T/C cg11266682 chr4:10021025 SLC2A9 0.73 10.8 0.7 1.4e-19 Bone mineral density; TGCT cis rs7666738 0.753 rs17483788 chr4:98985623 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3820068 0.705 rs16851727 chr1:15857918 C/T cg05660106 chr1:15850417 CASP9 1.15 13.74 0.78 1.14e-26 Systolic blood pressure; TGCT cis rs79057730 0.684 rs6955004 chr7:790792 A/G cg06242242 chr7:766104 PRKAR1B;HEATR2 0.66 5.45 0.44 2.62e-7 Initial pursuit acceleration; TGCT cis rs2414095 0.527 rs8041967 chr15:51544324 G/A cg19946085 chr15:51559439 CYP19A1 -0.33 -4.68 -0.39 7.54e-6 Follicule stimulating hormone;Hormone measurements;Total body bone mineral density; TGCT cis rs35306767 0.903 rs11812523 chr10:915638 C/T cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs2147959 0.724 rs10753452 chr1:228724604 G/C cg22700015 chr1:228743131 NA -0.54 -4.59 -0.38 1.06e-5 Adult asthma; TGCT cis rs2439831 0.681 rs7168940 chr15:43633334 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.9 6.87 0.52 2.81e-10 Lung cancer in ever smokers; TGCT cis rs7100689 0.577 rs1143694 chr10:82040052 C/T cg01528321 chr10:82214614 TSPAN14 -0.7 -6.78 -0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs5750830 0.649 rs5757657 chr22:39798429 G/T cg01416388 chr22:39784598 NA -0.73 -7.59 -0.56 6.65e-12 Intelligence (multi-trait analysis); TGCT cis rs7826238 0.564 rs2921053 chr8:8319963 G/C cg06636001 chr8:8085503 FLJ10661 0.75 7.05 0.53 1.1e-10 Systolic blood pressure; TGCT trans rs2469997 1.000 rs2447176 chr8:120356892 G/A cg01792902 chr3:178864926 PIK3CA 0.84 6.81 0.52 3.74e-10 Hypertension (SNP x SNP interaction); TGCT cis rs3862260 1.000 rs3862260 chr1:120160789 G/A cg16322792 chr1:120165303 ZNF697 0.27 5.71 0.46 7.73e-8 Systemic lupus erythematosus; TGCT cis rs1018836 0.631 rs2205157 chr8:91472384 C/T cg16814680 chr8:91681699 NA -0.76 -7.45 -0.56 1.37e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2463822 1.000 rs12279819 chr11:62137245 G/A cg06239285 chr11:62104954 ASRGL1 -0.94 -6.61 -0.51 1.03e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9467711 0.606 rs2072806 chr6:26385093 C/G cg16898833 chr6:26189333 HIST1H4D 1.15 5.5 0.44 2.1e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10484885 0.763 rs56401039 chr6:90522486 C/T cg13799429 chr6:90582589 CASP8AP2 -0.46 -4.52 -0.38 1.43e-5 QRS interval (sulfonylurea treatment interaction); TGCT trans rs2727020 0.595 rs10839286 chr11:49497063 C/A cg03929089 chr4:120376271 NA -0.76 -9.15 -0.63 1.43e-15 Coronary artery disease; TGCT cis rs1062177 0.826 rs2915879 chr5:151147442 A/G cg00977110 chr5:151150581 G3BP1 0.4 4.67 0.39 7.61e-6 Preschool internalizing problems; TGCT cis rs6570726 0.791 rs952406 chr6:145925616 C/A cg05347473 chr6:146136440 FBXO30 0.5 4.61 0.38 9.98e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg21171335 chr12:122356390 WDR66 0.61 6.66 0.51 7.92e-10 Mean corpuscular volume; TGCT cis rs694739 0.687 rs11231771 chr11:64140642 T/G cg02228329 chr11:64053129 BAD;GPR137 0.7 6.8 0.52 4.02e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs735396 0.627 rs2264778 chr12:121450354 C/A cg02403541 chr12:121454288 C12orf43 0.86 9.16 0.64 1.35e-15 N-glycan levels; TGCT cis rs611744 0.967 rs653081 chr8:109230383 G/T cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs2288884 1.000 rs11669385 chr19:52571952 G/C cg13540795 chr19:52551618 ZNF432 -0.59 -4.98 -0.41 2.09e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs3858526 0.959 rs11039699 chr11:5951091 G/A cg05234568 chr11:5960015 NA -0.48 -4.77 -0.39 5.08e-6 DNA methylation (variation); TGCT cis rs2692947 0.644 rs1168970 chr2:96816606 C/T cg22654517 chr2:96458247 NA 0.23 4.86 0.4 3.42e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2535633 0.631 rs2581803 chr3:52994981 G/A cg05573699 chr3:52720067 GNL3;PBRM1 0.55 5.31 0.43 4.87e-7 Body mass index; TGCT cis rs11085466 1.000 rs75211977 chr19:21760201 G/A cg23026602 chr19:21646605 NA -0.57 -4.59 -0.38 1.07e-5 Colorectal or endometrial cancer; TGCT cis rs2153535 0.542 rs6905925 chr6:8440030 C/T cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs12477438 0.501 rs11688004 chr2:99735052 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs231779 0.628 rs12464033 chr2:204796094 G/A cg14577373 chr2:204102500 CYP20A1 -0.26 -4.45 -0.37 1.9e-5 Hypothyroidism;Tonsillectomy; TGCT cis rs9611565 0.694 rs11090056 chr22:42095904 A/C cg06634786 chr22:41940651 POLR3H 0.82 7.76 0.57 2.71e-12 Vitiligo; TGCT cis rs986417 0.901 rs1955693 chr14:61012331 T/C cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs2832191 0.655 rs2247110 chr21:30323888 G/A cg08807101 chr21:30365312 RNF160 -0.65 -6.08 -0.48 1.35e-8 Dental caries; TGCT cis rs7829975 0.714 rs7823757 chr8:8670177 T/A cg06636001 chr8:8085503 FLJ10661 0.61 5.46 0.44 2.47e-7 Mood instability; TGCT cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg16414030 chr3:133502952 NA -0.52 -7.29 -0.55 3.17e-11 Iron status biomarkers; TGCT cis rs854765 0.693 rs9907246 chr17:17770965 T/C cg04398451 chr17:18023971 MYO15A 0.29 4.55 0.38 1.26e-5 Total body bone mineral density; TGCT cis rs7937682 0.889 rs484013 chr11:111495779 G/A cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs263156 0.934 rs187810 chr6:142885758 A/G cg18419694 chr6:143832440 FUCA2 -0.38 -4.46 -0.37 1.79e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs2305707 0.867 rs4614671 chr15:51556594 C/T cg19946085 chr15:51559439 CYP19A1 0.49 5.2 0.42 8.08e-7 Height; TGCT cis rs2243480 0.901 rs73142137 chr7:65343442 A/T cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs60871478 0.838 rs7789321 chr7:800977 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.47 4.56 0.38 1.19e-5 Cerebrospinal P-tau181p levels; TGCT cis rs35883536 0.647 rs12046413 chr1:101047430 T/C cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs7213347 0.780 rs9892016 chr17:2146422 A/G cg13315690 chr17:1944831 OVCA2;DPH1 -0.35 -4.52 -0.38 1.45e-5 Total body bone mineral density; TGCT cis rs6088580 0.634 rs6059896 chr20:33111783 T/C cg06115741 chr20:33292138 TP53INP2 0.53 4.65 0.39 8.41e-6 Glomerular filtration rate (creatinine); TGCT cis rs2243480 1.000 rs55895244 chr7:65387678 C/G cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs6728642 0.908 rs56786766 chr2:98024901 T/C cg26665480 chr2:98280029 ACTR1B -0.93 -4.71 -0.39 6.65e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs7666738 0.539 rs13150465 chr4:99094892 C/T cg17366294 chr4:99064904 C4orf37 -0.73 -4.74 -0.39 5.81e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.606 rs3846447 chr4:99099907 G/A cg17366294 chr4:99064904 C4orf37 0.55 5.09 0.42 1.29e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.761 rs1456210 chr4:98645932 T/G cg18180107 chr4:99064573 C4orf37 0.52 5.05 0.41 1.53e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6693567 0.565 rs1776275 chr1:150269437 G/T cg09579323 chr1:150459698 TARS2 -0.52 -4.73 -0.39 6.09e-6 Migraine; TGCT trans rs1005277 0.579 rs1780139 chr10:38503018 C/T cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.71 7.58 0.56 6.92e-12 Blood metabolite levels; TGCT cis rs4665809 0.878 rs892448 chr2:26366205 A/G cg04944784 chr2:26401820 FAM59B -0.71 -6.31 -0.49 4.61e-9 Gut microbiome composition (summer); TGCT cis rs763014 0.931 rs710925 chr16:633354 G/A cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs9325144 0.681 rs7957376 chr12:39096518 C/T cg13010199 chr12:38710504 ALG10B 0.64 4.79 0.39 4.76e-6 Morning vs. evening chronotype; TGCT cis rs7095607 0.813 rs4518986 chr10:69932878 T/G cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.72e-6 Lung function (FVC); TGCT cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg18252515 chr7:66147081 NA -1.19 -7.67 -0.57 4.29e-12 Diabetic kidney disease; TGCT cis rs1799949 0.929 rs799905 chr17:41277187 G/C cg23758822 chr17:41437982 NA 0.67 6.72 0.52 5.83e-10 Menopause (age at onset); TGCT trans rs1814175 0.817 rs6486046 chr11:49997017 T/C cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs950776 0.518 rs4887063 chr15:78839715 C/T cg06917634 chr15:78832804 PSMA4 -0.77 -6.74 -0.52 5.25e-10 Sudden cardiac arrest; TGCT cis rs698833 0.548 rs6544760 chr2:44553014 C/T cg23552047 chr2:44669647 C2orf34 0.3 4.77 0.39 5.16e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg06675538 chr2:114033490 PAX8;LOC440839 -0.44 -4.88 -0.4 3.18e-6 Lymphocyte counts; TGCT cis rs6500602 0.647 rs1641868 chr16:4594503 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.55 0.45 1.62e-7 Schizophrenia; TGCT cis rs2017387 0.515 rs157550 chr19:50539371 G/A cg19230443 chr19:49950584 PIH1D1 -0.29 -4.69 -0.39 7.22e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs853679 0.517 rs9393897 chr6:28127710 G/T cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs8077577 0.895 rs11655797 chr17:18107850 C/T cg09161412 chr17:18057145 MYO15A -0.65 -5.25 -0.43 6.29e-7 Obesity-related traits; TGCT cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg12311346 chr5:56204834 C5orf35 -0.66 -6.37 -0.5 3.3e-9 Initial pursuit acceleration; TGCT cis rs4972806 0.849 rs2857535 chr2:177036211 G/A cg03152288 chr2:177042942 NA 0.63 5.5 0.44 2.08e-7 IgG glycosylation; TGCT cis rs9325144 0.505 rs901635 chr12:38646572 A/C cg13010199 chr12:38710504 ALG10B -0.56 -4.94 -0.41 2.52e-6 Morning vs. evening chronotype; TGCT cis rs12497850 0.931 rs7626445 chr3:49114544 C/T cg05785598 chr3:49045655 WDR6 0.36 4.77 0.39 5.17e-6 Parkinson's disease; TGCT cis rs73058052 0.597 rs56873913 chr19:50091199 T/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.6 4.6 0.38 1.01e-5 Fibrinogen levels; TGCT cis rs11676348 0.776 rs11690316 chr2:219017462 A/G cg00012203 chr2:219082015 ARPC2 -0.52 -5.0 -0.41 1.92e-6 Ulcerative colitis; TGCT cis rs17376456 0.877 rs10061080 chr5:93420559 A/G cg21475434 chr5:93447410 FAM172A 0.62 4.78 0.39 4.78e-6 Diabetic retinopathy; TGCT cis rs7635838 0.751 rs6442260 chr3:11590751 C/T cg00170343 chr3:11313890 ATG7 -0.71 -6.28 -0.49 5.26e-9 HDL cholesterol; TGCT cis rs8070128 0.601 rs8080602 chr17:17954728 G/C cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs9902453 0.967 rs60176674 chr17:28479854 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs5769765 0.773 rs6520065 chr22:50294470 A/T cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg23172400 chr8:95962367 TP53INP1 -0.35 -5.7 -0.46 8.33e-8 Type 2 diabetes; TGCT cis rs6987853 1.000 rs6987853 chr8:42457450 T/C cg20539142 chr8:42623718 CHRNA6 -0.2 -4.92 -0.4 2.67e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs4665809 1.000 rs4233708 chr2:26291345 C/T cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs3772130 1.000 rs2070180 chr3:121351338 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.54 -4.95 -0.41 2.41e-6 Cognitive performance; TGCT cis rs3808502 0.527 rs56177149 chr8:11247298 G/A cg21775007 chr8:11205619 TDH 0.6 5.82 0.46 4.67e-8 Neuroticism; TGCT cis rs7085104 0.632 rs3781287 chr10:104595420 A/C cg04362960 chr10:104952993 NT5C2 0.54 4.79 0.39 4.72e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs11119608 0.846 rs7553708 chr1:210978485 C/T cg24524366 chr1:211689016 NA 0.5 4.51 0.38 1.46e-5 Cancer; TGCT cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs9322193 0.923 rs4870529 chr6:150037572 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs854765 0.647 rs62073573 chr17:17976354 G/A cg09796270 chr17:17721594 SREBF1 0.24 4.87 0.4 3.39e-6 Total body bone mineral density; TGCT cis rs10782582 0.593 rs12131493 chr1:76139172 G/A cg03433033 chr1:76189801 ACADM -0.64 -7.28 -0.55 3.39e-11 Daytime sleep phenotypes; TGCT cis rs3741404 0.609 rs641378 chr11:63869493 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.72 7.32 0.55 2.78e-11 Platelet count; TGCT cis rs700590 0.723 rs304153 chr5:88121188 A/T cg22951263 chr5:87985283 NA -0.55 -5.18 -0.42 8.87e-7 Educational attainment (years of education); TGCT cis rs11031096 0.746 rs7949663 chr11:4170123 A/G cg18678763 chr11:4115507 RRM1 -0.48 -6.23 -0.49 6.52e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs939658 0.805 rs2010524 chr15:79435825 G/T cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs7726839 0.540 rs11739847 chr5:609661 G/A cg16624210 chr5:671434 TPPP 0.44 4.75 0.39 5.46e-6 Obesity-related traits; TGCT cis rs17030434 1.000 rs17030434 chr4:154703596 A/G cg14289246 chr4:154710475 SFRP2 -1.04 -8.24 -0.59 2.04e-13 Electrocardiographic conduction measures; TGCT cis rs7666738 0.830 rs13129479 chr4:98987860 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7617773 0.817 rs9830016 chr3:48282494 A/G cg11946769 chr3:48343235 NME6 0.74 6.39 0.5 3.01e-9 Coronary artery disease; TGCT cis rs10760123 1 rs10760123 chr9:123650534 T/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.5 5.5 0.44 2.03e-7 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12701220 0.520 rs7803208 chr7:1162084 C/T cg20824189 chr7:1704082 NA -0.44 -4.55 -0.38 1.25e-5 Bronchopulmonary dysplasia; TGCT cis rs727563 0.555 rs5751136 chr22:42075581 T/A cg06634786 chr22:41940651 POLR3H 0.89 8.47 0.61 5.95e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs12477438 0.798 rs6705583 chr2:99602625 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.18 -0.49 8.51e-9 Chronic sinus infection; TGCT cis rs60843830 1.000 rs55946380 chr2:268293 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.73 7.41 0.55 1.74e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2594989 1.000 rs2595002 chr3:11373700 G/A cg00170343 chr3:11313890 ATG7 0.62 4.78 0.39 4.86e-6 Circulating chemerin levels; TGCT cis rs34526934 0.566 rs1374325 chr2:177043971 G/A cg00278547 chr2:177037212 HOXD3 -0.36 -4.45 -0.37 1.85e-5 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs11718455 0.960 rs13083325 chr3:44005333 T/C cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs739496 0.542 rs7312913 chr12:111793552 A/G cg10833066 chr12:111807467 FAM109A 0.44 7.52 0.56 9.58e-12 Platelet count; TGCT cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs709400 0.663 rs11623869 chr14:103883633 G/T cg26031613 chr14:104095156 KLC1 0.84 9.43 0.65 2.98e-16 Body mass index; TGCT cis rs3008870 1.000 rs1137656 chr1:67451602 A/C cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs2243480 1.000 rs387676 chr7:65598220 C/T cg18252515 chr7:66147081 NA -1.22 -7.98 -0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs6951245 0.554 rs35126802 chr7:1134842 C/T cg03188948 chr7:1209495 NA 0.52 5.4 0.44 3.29e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg03404566 chr17:6899310 ALOX12 0.45 5.29 0.43 5.4e-7 Tonsillectomy; TGCT cis rs5769707 0.967 rs17182154 chr22:49990470 A/G cg05373962 chr22:49881684 NA -0.29 -6.03 -0.48 1.71e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs73198271 0.960 rs73198286 chr8:8612022 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.65 -0.39 8.24e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12497850 0.931 rs7623023 chr3:48914238 G/A cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs4819852 0.958 rs12628032 chr22:19967980 C/T cg07821417 chr22:19972146 ARVCF 0.21 5.37 0.43 3.81e-7 Pulse pressure; TGCT trans rs877282 0.945 rs10904554 chr10:786768 T/C cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs6714788 0.503 rs1370356 chr2:100675241 G/C cg22139774 chr2:100720529 AFF3 -0.41 -6.39 -0.5 2.99e-9 Intelligence (multi-trait analysis); TGCT cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.79 0.4 4.66e-6 Menarche (age at onset); TGCT cis rs6089584 0.888 rs6142927 chr20:60605848 A/G cg16423285 chr20:60520624 NA -0.57 -5.93 -0.47 2.83e-8 Body mass index; TGCT cis rs2016266 0.819 rs7397757 chr12:53652684 A/G cg16917193 chr12:54089295 NA -0.62 -4.56 -0.38 1.19e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs8008002 0.965 rs8007789 chr14:75865404 G/A cg20011974 chr14:75469661 EIF2B2 -0.5 -4.48 -0.37 1.65e-5 Response to paliperidone in schizophrenia (positive Marder score); TGCT cis rs6121246 0.609 rs6088997 chr20:30289824 A/G cg10886678 chr20:30946050 ASXL1 0.55 4.49 0.37 1.64e-5 Mean corpuscular hemoglobin; TGCT cis rs7226408 0.857 rs72888916 chr18:34521336 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs896854 0.902 rs726816 chr8:95968413 T/G cg09323728 chr8:95962352 TP53INP1 -0.52 -6.68 -0.51 7.06e-10 Type 2 diabetes; TGCT cis rs1215050 0.791 rs7681599 chr4:98664109 C/T cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1867631 0.958 rs7520226 chr1:67080995 T/G cg13052034 chr1:66999238 SGIP1 0.6 5.17 0.42 9.19e-7 Menopause (age at onset); TGCT cis rs8068544 0.748 rs75881902 chr17:40156612 C/A cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.07 -5.1 -0.42 1.26e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg25767906 chr1:53392781 SCP2 -0.56 -6.45 -0.5 2.25e-9 Monocyte count; TGCT cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs9911578 0.900 rs8067264 chr17:57182793 G/C cg05425664 chr17:57184151 TRIM37 -0.68 -6.9 -0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs17027225 chr4:99028564 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs72627509 0.857 rs781658 chr4:57779567 G/A cg26694713 chr4:57773883 REST 0.73 6.53 0.51 1.5e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9393777 0.513 rs11967852 chr6:26612870 G/T cg15659132 chr6:26577336 NA -0.79 -5.55 -0.45 1.66e-7 Intelligence (multi-trait analysis); TGCT cis rs10876993 0.890 rs2619441 chr12:58083015 C/A cg15848620 chr12:58087721 OS9 -0.72 -5.98 -0.47 2.25e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs9467773 0.511 rs11755443 chr6:26891603 T/C cg15659132 chr6:26577336 NA 0.71 7.0 0.53 1.42e-10 Intelligence (multi-trait analysis); TGCT cis rs9660180 0.935 rs2180311 chr1:1748734 T/C cg17747265 chr1:1875780 NA -0.42 -7.78 -0.57 2.48e-12 Body mass index; TGCT cis rs79349575 0.783 rs4793992 chr17:47008207 A/G cg27201301 chr17:47039149 GIP 0.25 4.49 0.37 1.58e-5 Type 2 diabetes; TGCT trans rs1814175 0.803 rs11040451 chr11:49650639 C/T cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs2404602 0.692 rs4886503 chr15:77108874 C/T cg22467129 chr15:76604101 ETFA 0.43 4.89 0.4 3.04e-6 Blood metabolite levels; TGCT cis rs4689388 0.816 rs13147655 chr4:6293474 A/G cg00701064 chr4:6280414 WFS1 0.39 4.91 0.4 2.86e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9372498 0.536 rs9489399 chr6:118767147 C/A cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs58688157 0.705 rs12272434 chr11:615011 A/T cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs1865760 0.786 rs2164487 chr6:25950800 A/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs10782582 0.546 rs79652169 chr1:76233882 G/A cg22875332 chr1:76189707 ACADM -0.45 -4.93 -0.4 2.55e-6 Daytime sleep phenotypes; TGCT cis rs66573146 1.000 rs73088528 chr4:6967747 G/C cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs7617480 0.648 rs6801211 chr3:48774420 C/G cg07636037 chr3:49044803 WDR6 0.76 6.36 0.5 3.6e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs12477438 0.520 rs13798 chr2:99813614 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.04 0.76 5.31e-25 Chronic sinus infection; TGCT cis rs7267979 1.000 rs2257432 chr20:25271086 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9486719 0.895 rs3734238 chr6:96996228 A/T cg18709589 chr6:96969512 KIAA0776 -0.76 -5.32 -0.43 4.63e-7 Migraine;Coronary artery disease; TGCT cis rs8051149 0.688 rs55776570 chr16:87869516 C/G cg01412419 chr16:87856264 NA 0.5 5.72 0.46 7.68e-8 Blood metabolite levels; TGCT cis rs10908458 0.584 rs10908454 chr1:155066416 C/T cg23973274 chr1:155060172 NA -0.27 -5.12 -0.42 1.15e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7428 0.527 rs4459734 chr2:85547429 G/T cg03728395 chr2:85555865 TGOLN2 -0.31 -5.17 -0.42 9.27e-7 Ear protrusion; TGCT cis rs4819052 0.788 rs4819051 chr21:46693128 C/T cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12477438 0.520 rs2309581 chr2:99784292 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.86 -8.6 -0.61 2.97e-14 Chronic sinus infection; TGCT cis rs2439831 0.717 rs2447198 chr15:43895118 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.85 5.36 0.43 4e-7 Lung cancer in ever smokers; TGCT cis rs7927771 0.832 rs56030824 chr11:47397353 G/A cg10139015 chr11:47448256 PSMC3 0.52 4.5 0.37 1.54e-5 Subjective well-being; TGCT cis rs2153535 0.601 rs9505474 chr6:8539794 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs2455799 0.552 rs2470519 chr3:15762847 G/A cg16303742 chr3:15540471 COLQ -0.26 -4.96 -0.41 2.26e-6 Mean platelet volume; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.5 5.41 0.44 3.18e-7 Lymphocyte counts; TGCT cis rs12776158 0.685 rs60677596 chr10:71216880 A/G cg12610070 chr10:71211762 TSPAN15 -0.59 -5.17 -0.42 9.16e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs7267979 1.000 rs6115182 chr20:25410259 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs597539 0.652 rs611046 chr11:68631704 A/G cg21862992 chr11:68658383 NA 0.45 6.2 0.49 7.55e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs916888 0.610 rs199436 chr17:44789285 C/T cg22433210 chr17:43662623 NA -0.9 -7.78 -0.57 2.37e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17665859 0.687 rs117278497 chr8:495397 C/T cg17960703 chr8:356704 FBXO25 1.21 4.88 0.4 3.25e-6 Bilirubin levels; TGCT cis rs1371867 0.875 rs1788169 chr8:101326314 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs6087771 0.642 rs6060403 chr20:30221104 C/A cg13852791 chr20:30311386 BCL2L1 0.77 6.53 0.51 1.51e-9 Subcortical brain region volumes;Putamen volume; TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg18538332 chr22:24372958 LOC391322 -0.96 -11.29 -0.71 9.39e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs8070740 0.786 rs12761 chr17:5326145 C/G cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs9467773 0.620 rs2504540 chr6:26641626 A/G cg02458000 chr6:26745757 NA 0.52 4.86 0.4 3.41e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.966 rs2500417 chr20:25383287 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1814175 0.817 rs7109440 chr11:49966296 C/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs7172809 0.573 rs74025104 chr15:77552587 G/A cg22256960 chr15:77711686 NA -0.48 -4.67 -0.39 7.76e-6 Glucose homeostasis traits; TGCT cis rs13064411 0.696 rs2087129 chr3:113142769 T/A cg18753928 chr3:113234510 CCDC52 -0.67 -5.12 -0.42 1.14e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs3617 0.625 rs7617468 chr3:52849549 T/C cg10802521 chr3:52805072 NEK4 -0.6 -6.97 -0.53 1.63e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7223966 1.000 rs16947042 chr17:61766457 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 5.17 0.42 8.94e-7 Hip circumference adjusted for BMI;Body mass index; TGCT trans rs6089829 0.962 rs2314130 chr20:61665129 G/T cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs6582630 0.555 rs7301250 chr12:38596244 G/T cg13010199 chr12:38710504 ALG10B 0.65 5.07 0.41 1.41e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1903068 0.853 rs28411232 chr4:56000009 A/T cg16572876 chr4:56024045 NA 0.43 4.94 0.41 2.43e-6 Endometriosis; TGCT cis rs11958404 0.719 rs72818153 chr5:157487035 T/C cg05962755 chr5:157440814 NA 0.35 4.55 0.38 1.27e-5 IgG glycosylation; TGCT cis rs2404602 0.536 rs17364330 chr15:76765385 A/T cg26408565 chr15:76604113 ETFA -0.38 -5.26 -0.43 6.01e-7 Blood metabolite levels; TGCT cis rs17376456 0.877 rs17083455 chr5:93446380 A/C cg21475434 chr5:93447410 FAM172A 0.58 4.57 0.38 1.16e-5 Diabetic retinopathy; TGCT trans rs7613875 0.620 rs7624030 chr3:50071279 A/C cg21659725 chr3:3221576 CRBN -0.7 -7.95 -0.58 9.9e-13 Body mass index; TGCT cis rs4689388 0.926 rs11725494 chr4:6293855 C/T cg25554036 chr4:6271136 WFS1 0.56 7.96 0.58 9.12e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg19774624 chr17:42201019 HDAC5 0.84 8.44 0.6 7.03e-14 Total body bone mineral density; TGCT cis rs6546537 0.955 rs2312215 chr2:69839825 T/A cg10773587 chr2:69614142 GFPT1 -0.72 -6.27 -0.49 5.41e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs700651 0.821 rs770661 chr2:198725444 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial aneurysm; TGCT cis rs4665809 1.000 rs4233709 chr2:26291493 C/T cg04944784 chr2:26401820 FAM59B 0.65 5.37 0.43 3.74e-7 Gut microbiome composition (summer); TGCT cis rs597539 0.552 rs6591360 chr11:68718669 G/T cg21862992 chr11:68658383 NA 0.46 6.25 0.49 5.91e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2235642 0.859 rs9927529 chr16:1619488 C/T cg00463982 chr16:1583984 IFT140;TMEM204 -0.3 -4.86 -0.4 3.47e-6 Coronary artery disease; TGCT cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg24675658 chr1:53192096 ZYG11B 0.75 8.72 0.62 1.48e-14 Monocyte count; TGCT cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs11648796 0.718 rs62032512 chr16:764826 C/T cg00908189 chr16:619842 PIGQ 0.72 5.76 0.46 6.31e-8 Height; TGCT cis rs6426558 0.537 rs6692080 chr1:227390162 C/T cg10327440 chr1:227177885 CDC42BPA -0.6 -7.06 -0.54 1.04e-10 Neutrophil percentage of white cells; TGCT cis rs7095607 1.000 rs7095607 chr10:69957350 G/A cg18986048 chr10:69913749 MYPN 0.45 4.83 0.4 3.87e-6 Lung function (FVC); TGCT cis rs754133 1.000 rs754133 chr12:54418920 C/T cg16264616 chr12:54390824 NA 0.3 4.64 0.38 8.68e-6 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs7017914 0.934 rs2639904 chr8:71917130 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.31 -0.43 4.8e-7 Bone mineral density; TGCT cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg03806693 chr22:41940476 POLR3H -1.14 -13.38 -0.77 8.05e-26 Vitiligo; TGCT cis rs6977955 1.000 rs4722760 chr7:28172183 C/T cg23620719 chr7:28220237 JAZF1 -0.58 -4.55 -0.38 1.24e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4975616 0.869 rs370348 chr5:1331219 A/G cg07493874 chr5:1342172 CLPTM1L -0.28 -6.88 -0.53 2.69e-10 Lung cancer; TGCT cis rs12579753 0.913 rs17749243 chr12:82178079 A/C cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg27454412 chr7:1067447 C7orf50 0.56 4.65 0.39 8.33e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836974 0.897 rs8133146 chr21:40614298 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.65 0.65 9.11e-17 Cognitive function; TGCT cis rs4803468 0.935 rs284660 chr19:41932084 G/T cg09537434 chr19:41945824 ATP5SL -0.93 -10.44 -0.68 1.11e-18 Height; TGCT cis rs6121246 0.559 rs6060915 chr20:30330306 A/G cg13852791 chr20:30311386 BCL2L1 0.81 7.92 0.58 1.17e-12 Mean corpuscular hemoglobin; TGCT cis rs9322193 0.923 rs4870267 chr6:149992708 C/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2153535 0.580 rs1889715 chr6:8443475 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs3820928 0.709 rs2894627 chr2:227910171 A/G cg11843606 chr2:227700838 RHBDD1 -0.51 -4.66 -0.39 8.18e-6 Pulmonary function; TGCT cis rs3803170 0.513 rs10774623 chr12:111833589 C/T cg10833066 chr12:111807467 FAM109A -0.38 -5.67 -0.45 9.43e-8 Mean corpuscular hemoglobin; TGCT cis rs7267979 0.844 rs6107027 chr20:25288632 A/G cg03522245 chr20:25566470 NINL 0.54 5.58 0.45 1.46e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs7715806 0.500 rs72633982 chr5:75001321 C/T cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs13191362 1.000 rs2156257 chr6:163100710 G/T cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.09 0.59 4.62e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9894429 1.000 rs9747349 chr17:79584297 C/T cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs950169 0.922 rs11630507 chr15:85095725 A/G cg11189052 chr15:85197271 WDR73 0.8 6.64 0.51 8.83e-10 Schizophrenia; TGCT cis rs903263 1.000 rs903263 chr1:84622513 G/T cg09664975 chr1:84543551 PRKACB 0.47 4.48 0.37 1.65e-5 Breast cancer (male); TGCT cis rs939574 1.000 rs1024131 chr2:220117458 G/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.05 6.46 0.5 2.12e-9 Platelet distribution width; TGCT cis rs2228479 0.718 rs11645376 chr16:89912281 G/C cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs1691799 0.899 rs1060724 chr12:66740444 T/C cg16791601 chr12:66731901 HELB -0.29 -6.31 -0.49 4.41e-9 White blood cell count (basophil); TGCT cis rs1218582 0.774 rs4845683 chr1:154877407 T/C cg06221963 chr1:154839813 KCNN3 -0.79 -15.15 -0.81 5.4e-30 Prostate cancer; TGCT cis rs7432375 0.901 rs1681817 chr3:136473728 C/T cg12473912 chr3:136751656 NA -0.36 -5.21 -0.42 7.55e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7568458 0.516 rs62166769 chr2:85812784 T/A cg02493740 chr2:85810744 VAMP5 -0.27 -4.61 -0.38 9.88e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3617 0.625 rs56019197 chr3:52874753 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.76 0.39 5.32e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs533581 0.873 rs579740 chr16:88973937 A/G cg05579598 chr16:88989069 CBFA2T3 -0.34 -4.49 -0.37 1.6e-5 Social autistic-like traits; TGCT cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg00786635 chr1:25594202 NA 0.62 6.51 0.5 1.67e-9 Erythrocyte sedimentation rate; TGCT cis rs8062405 1.000 rs80275162 chr16:28863517 T/A cg09754948 chr16:28834200 ATXN2L 0.59 4.46 0.37 1.84e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6589563 0.737 rs61905088 chr11:116619867 C/A cg20660624 chr11:117307972 DSCAML1 -0.35 -4.56 -0.38 1.19e-5 Eosinophil counts; TGCT cis rs11785400 0.793 rs4403386 chr8:143736770 C/G cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs2836974 0.931 rs2776309 chr21:40715791 A/G cg11890956 chr21:40555474 PSMG1 0.99 9.11 0.63 1.78e-15 Cognitive function; TGCT cis rs3741404 0.825 rs11604782 chr11:63946650 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.94 10.77 0.7 1.71e-19 Platelet count; TGCT cis rs981844 0.714 rs2405204 chr4:154705248 A/G cg14289246 chr4:154710475 SFRP2 -0.92 -8.41 -0.6 8.38e-14 Response to statins (LDL cholesterol change); TGCT cis rs4713118 0.513 rs149897 chr6:28006650 A/G cg10876282 chr6:28092338 ZSCAN16 0.51 4.56 0.38 1.19e-5 Parkinson's disease; TGCT trans rs6762477 0.748 rs11714799 chr3:50217899 T/G cg21659725 chr3:3221576 CRBN -0.67 -7.57 -0.56 7.57e-12 Menarche (age at onset); TGCT cis rs28595532 0.920 rs55649377 chr4:119752745 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs79387448 0.638 rs13405222 chr2:102981891 T/C cg09003973 chr2:102972529 NA 1.47 10.36 0.68 1.69e-18 Gut microbiota (bacterial taxa); TGCT cis rs11599315 0.507 rs12217329 chr10:1341897 A/G cg27336068 chr10:1336103 ADARB2 -0.34 -5.47 -0.44 2.41e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs7666738 0.830 rs3896704 chr4:99034252 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.504 rs9328472 chr6:8470848 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg17264618 chr3:40429014 ENTPD3 0.33 4.85 0.4 3.66e-6 Renal cell carcinoma; TGCT cis rs10791323 0.604 rs10791324 chr11:133704065 T/C cg15485101 chr11:133734466 NA 0.41 5.11 0.42 1.16e-6 Childhood ear infection; TGCT cis rs9733 0.596 rs72700897 chr1:150626038 C/G cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs6882046 0.513 rs628158 chr5:88041781 G/A cg24804195 chr5:87968844 LOC645323 -0.6 -6.06 -0.48 1.48e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs7819412 0.522 rs10088853 chr8:10987967 G/A cg21775007 chr8:11205619 TDH -0.6 -5.34 -0.43 4.3e-7 Triglycerides; TGCT cis rs13064411 0.696 rs869343 chr3:113226705 C/T cg18753928 chr3:113234510 CCDC52 -0.71 -5.78 -0.46 5.63e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7829975 0.658 rs907181 chr8:8702875 T/C cg08975724 chr8:8085496 FLJ10661 0.49 4.48 0.37 1.65e-5 Mood instability; TGCT cis rs7267979 1.000 rs1888998 chr20:25291826 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17114671 1.000 rs8008440 chr14:21156448 A/G cg19983597 chr14:21852154 SUPT16H -0.87 -4.57 -0.38 1.18e-5 Blood protein levels; TGCT cis rs7201929 0.801 rs9933198 chr16:28888409 C/T cg09754948 chr16:28834200 ATXN2L -0.64 -5.08 -0.42 1.35e-6 QT interval; TGCT cis rs589249 0.963 rs636521 chr1:37158071 A/C cg04012535 chr1:37176647 NA -0.3 -4.86 -0.4 3.47e-6 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs9993613 1.000 rs4694502 chr4:73496157 G/A cg15102770 chr4:73434591 ADAMTS3 -0.5 -4.59 -0.38 1.07e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs58106596 0.527 rs1866599 chr2:232726300 C/T cg26500773 chr2:232646331 PDE6D -0.64 -4.75 -0.39 5.44e-6 White blood cell count;Lymphocyte counts; TGCT cis rs832540 0.618 rs2548663 chr5:56172778 G/A cg24531977 chr5:56204891 C5orf35 -0.52 -5.02 -0.41 1.73e-6 Coronary artery disease; TGCT cis rs9902453 0.967 rs7222685 chr17:28496430 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs11239930 0.538 rs719969 chr1:146555660 G/A cg00044796 chr1:146552390 NA -0.35 -4.5 -0.37 1.54e-5 AIDS progression; TGCT cis rs7582180 0.629 rs4851294 chr2:100941109 C/T cg14675211 chr2:100938903 LONRF2 0.54 5.33 0.43 4.39e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.723 rs35327100 chr4:98977788 C/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17376456 0.877 rs10040648 chr5:93490301 G/C cg25358565 chr5:93447407 FAM172A 0.97 8.3 0.6 1.46e-13 Diabetic retinopathy; TGCT cis rs371025208 1 rs371025208 chr20:43928602 TGGGTGTGTGTGTGTAGGG/T cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -6.93 -0.53 2.04e-10 Parental longevity (mother's age at death); TGCT cis rs7809950 1.000 rs10276604 chr7:107216738 C/T cg23024343 chr7:107201750 COG5 0.32 4.85 0.4 3.66e-6 Coronary artery disease; TGCT cis rs2070488 0.745 rs9838792 chr3:38546726 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.4 -0.5 2.93e-9 Electrocardiographic conduction measures; TGCT cis rs13217239 0.646 rs35691005 chr6:26972070 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 0.4 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs9303401 0.538 rs3785493 chr17:56472119 G/T cg25039879 chr17:56429692 SUPT4H1 -0.57 -4.79 -0.4 4.67e-6 Cognitive test performance; TGCT cis rs9611565 0.559 rs5758412 chr22:42080803 T/A cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Vitiligo; TGCT cis rs6570726 0.967 rs374728 chr6:145854598 T/A cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2486288 0.656 rs1719232 chr15:45572072 A/G cg26924012 chr15:45694286 SPATA5L1 -0.83 -8.38 -0.6 9.8e-14 Glomerular filtration rate; TGCT cis rs61990749 0.597 rs8016416 chr14:78213100 T/A cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs7666738 0.830 rs2865990 chr4:99067399 C/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6770219 0.516 rs73182263 chr3:186135138 T/G cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg16423285 chr20:60520624 NA -0.7 -7.43 -0.55 1.56e-11 Body mass index; TGCT cis rs7666738 0.830 rs13148913 chr4:99009732 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8072100 1.000 rs8072100 chr17:45674687 A/T cg08085267 chr17:45401833 C17orf57 0.47 5.13 0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4665809 1.000 rs750450 chr2:26324631 A/G cg04944784 chr2:26401820 FAM59B -0.71 -6.59 -0.51 1.11e-9 Gut microbiome composition (summer); TGCT cis rs2486288 0.656 rs8041702 chr15:45547093 C/T cg14582100 chr15:45693742 SPATA5L1 -0.44 -4.98 -0.41 2.1e-6 Glomerular filtration rate; TGCT cis rs9660180 0.780 rs12038111 chr1:1703849 T/C cg20999797 chr1:1681921 NA 0.18 4.77 0.39 5e-6 Body mass index; TGCT cis rs10992471 0.533 rs331381 chr9:95249859 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.55 5.31 0.43 4.9e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2075165 0.901 rs1804999 chr1:156219450 A/G cg20302342 chr1:156215951 PAQR6 0.39 5.64 0.45 1.12e-7 Tonsillectomy; TGCT cis rs9560113 1.000 rs9555809 chr13:112181401 T/C cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs7666738 0.570 rs11097612 chr4:99079772 T/C cg05340658 chr4:99064831 C4orf37 0.44 4.8 0.4 4.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs826838 0.967 rs11169169 chr12:39093153 A/C cg26384229 chr12:38710491 ALG10B 1.06 10.4 0.68 1.35e-18 Heart rate; TGCT cis rs875971 1.000 rs2420820 chr7:66091907 T/C cg11764359 chr7:65958608 NA -0.59 -5.2 -0.42 8.12e-7 Aortic root size; TGCT cis rs6540559 0.673 rs17015309 chr1:210007218 C/T cg21951975 chr1:209979733 IRF6 0.64 4.82 0.4 4.12e-6 Cleft lip with or without cleft palate; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg04234412 chr22:24373322 LOC391322 0.94 12.53 0.75 9.02e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17376456 0.757 rs10476591 chr5:93333723 G/C cg21475434 chr5:93447410 FAM172A 0.63 4.75 0.39 5.58e-6 Diabetic retinopathy; TGCT cis rs17384381 1.000 rs12140935 chr1:85855716 G/A cg16011679 chr1:85725395 C1orf52 0.8 6.45 0.5 2.21e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs250677 0.687 rs40522 chr5:148442295 G/A cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs7666738 0.830 rs2114425 chr4:99023967 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.64 0.45 1.09e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3784262 0.740 rs4646598 chr15:58300328 G/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.28 -0.49 5.12e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg25660036 chr4:7070649 GRPEL1 -0.66 -5.79 -0.46 5.38e-8 Monocyte percentage of white cells; TGCT cis rs1372520 0.748 rs2737002 chr4:90753180 A/G cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs2404618 0.506 rs12156177 chr8:1493684 C/T cg13402656 chr8:1511478 DLGAP2 -0.31 -5.51 -0.44 2e-7 Lung cancer; TGCT cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.6 4.96 0.41 2.27e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs916888 0.821 rs199525 chr17:44847834 T/G cg07870213 chr5:140052090 DND1 0.61 7.51 0.56 9.93e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2816062 0.813 rs725389 chr1:18881980 G/A cg18795169 chr1:18902165 NA -0.59 -13.16 -0.76 2.73e-25 Urate levels in lean individuals; TGCT cis rs2404602 0.669 rs17464903 chr15:77195486 A/G cg26408565 chr15:76604113 ETFA -0.36 -4.54 -0.38 1.31e-5 Blood metabolite levels; TGCT cis rs478304 0.627 rs11227254 chr11:65454000 A/G cg17480646 chr11:65405466 SIPA1 -0.63 -8.47 -0.61 6.08e-14 Acne (severe); TGCT cis rs12477438 0.765 rs28648058 chr2:99696417 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -5.07 -0.41 1.4e-6 Chronic sinus infection; TGCT cis rs2204008 0.627 rs10878488 chr12:38148666 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.15 0.42 1.01e-6 Bladder cancer; TGCT cis rs2204008 0.627 rs1851117 chr12:38398987 G/T cg13010199 chr12:38710504 ALG10B 0.59 4.68 0.39 7.35e-6 Bladder cancer; TGCT cis rs36051895 0.559 rs7874495 chr9:5209804 A/G cg02405213 chr9:5042618 JAK2 -0.65 -8.46 -0.61 6.13e-14 Pediatric autoimmune diseases; TGCT cis rs10114408 0.918 rs2153065 chr9:96644415 G/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Mean corpuscular hemoglobin; TGCT cis rs7614311 0.681 rs73117042 chr3:63896543 T/C cg22134162 chr3:63841271 THOC7 -0.4 -5.16 -0.42 9.41e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs1580019 0.534 rs13237495 chr7:32560687 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.86 0.4 3.43e-6 Cognitive ability; TGCT cis rs1018836 0.505 rs7015030 chr8:91460331 T/C cg16814680 chr8:91681699 NA -0.64 -6.19 -0.49 7.91e-9 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9409154 1.000 rs9409154 chr9:118202716 T/C cg14094498 chr9:119000864 PAPPA 0.21 4.48 0.37 1.67e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs9611565 0.512 rs1983576 chr22:42166486 G/A cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs3733585 0.563 rs881971 chr4:9930962 A/G cg11266682 chr4:10021025 SLC2A9 -0.51 -6.32 -0.49 4.35e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1371867 0.846 rs1660345 chr8:101322762 C/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs826838 1.000 rs11183196 chr12:38685915 G/T cg26384229 chr12:38710491 ALG10B 1.12 11.32 0.71 7.88e-21 Heart rate; TGCT cis rs1153858 1.000 rs11070457 chr15:45686943 A/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs13256369 0.802 rs2280560 chr8:8560602 C/T cg18904891 chr8:8559673 CLDN23 0.57 5.04 0.41 1.6e-6 Obesity-related traits; TGCT cis rs9899728 0.539 rs11077772 chr17:73035698 C/T cg27626185 chr17:73056755 KCTD2 -0.99 -7.93 -0.58 1.07e-12 Alzheimer's disease or small vessel stroke; TGCT cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg05025164 chr4:1340916 KIAA1530 0.8 6.69 0.51 7.02e-10 Longevity; TGCT cis rs34517613 0.589 rs12937920 chr17:26590657 C/T cg03094083 chr17:26864469 FOXN1 0.31 4.84 0.4 3.74e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs17376456 0.569 rs2045020 chr5:93224466 T/C cg21475434 chr5:93447410 FAM172A -0.69 -5.2 -0.42 7.83e-7 Diabetic retinopathy; TGCT cis rs4268898 0.722 rs10445893 chr2:24407128 A/G cg02683114 chr2:24398427 C2orf84 0.19 4.76 0.39 5.37e-6 Asthma; TGCT cis rs782590 0.774 rs2627773 chr2:55900459 A/G cg03859395 chr2:55845619 SMEK2 0.85 9.64 0.65 9.63e-17 Metabolic syndrome; TGCT cis rs9467711 1.000 rs6939799 chr6:26328366 G/A cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6840360 0.555 rs4554052 chr4:152726610 T/C cg17479576 chr4:152424074 FAM160A1 0.46 4.83 0.4 3.88e-6 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.791 rs443628 chr6:145883484 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.04 0.41 1.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs17030434 0.906 rs12641631 chr4:154665279 A/G cg14289246 chr4:154710475 SFRP2 -0.88 -7.18 -0.54 5.68e-11 Electrocardiographic conduction measures; TGCT cis rs1215050 0.791 rs783950 chr4:98878395 C/T cg17366294 chr4:99064904 C4orf37 -0.57 -6.08 -0.48 1.38e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4851254 0.618 rs35730185 chr2:100648085 G/A cg22139774 chr2:100720529 AFF3 -0.45 -4.9 -0.4 2.94e-6 Intelligence (multi-trait analysis); TGCT cis rs9790314 0.846 rs4290817 chr3:160967354 G/A cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs12989701 1.000 rs13009551 chr2:127889118 C/T cg08168897 chr2:127865431 BIN1 0.59 5.76 0.46 6.14e-8 Alzheimer's disease (late onset); TGCT cis rs1577917 1.000 rs12207305 chr6:86723502 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs17384381 0.859 rs28529751 chr1:85910951 G/A cg16011679 chr1:85725395 C1orf52 0.83 6.79 0.52 4.16e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs11031096 0.782 rs2165728 chr11:4147004 T/C cg18678763 chr11:4115507 RRM1 -0.47 -6.01 -0.47 1.91e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg25767906 chr1:53392781 SCP2 0.47 5.26 0.43 6.03e-7 Monocyte count; TGCT cis rs9419702 0.568 rs7093241 chr10:133556596 G/A cg23460707 chr10:133558971 NA 0.42 4.68 0.39 7.48e-6 Survival in rectal cancer; TGCT cis rs9894429 0.608 rs7406382 chr17:79597786 T/C cg21028142 chr17:79581711 NPLOC4 0.28 5.75 0.46 6.54e-8 Eye color traits; TGCT cis rs10089 0.953 rs17164427 chr5:127361736 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.74 -6.93 -0.53 2e-10 Ileal carcinoids; TGCT cis rs1801251 1.000 rs35085837 chr2:233624363 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs459571 0.916 rs467303 chr9:136904835 C/T cg14405625 chr9:136855902 VAV2 -0.3 -4.55 -0.38 1.28e-5 Platelet distribution width; TGCT cis rs733175 0.855 rs9291641 chr4:10007259 C/T cg00071950 chr4:10020882 SLC2A9 0.51 4.53 0.38 1.35e-5 Psychosis and Alzheimer's disease; TGCT cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg13393036 chr8:95962371 TP53INP1 -0.63 -8.66 -0.61 2.14e-14 Type 2 diabetes; TGCT cis rs4808199 0.947 rs751858 chr19:19602821 G/C cg03709012 chr19:19516395 GATAD2A 0.97 7.45 0.56 1.35e-11 Nonalcoholic fatty liver disease; TGCT cis rs9303401 0.614 rs17175663 chr17:57108437 G/C cg25039879 chr17:56429692 SUPT4H1 0.54 4.84 0.4 3.85e-6 Cognitive test performance; TGCT cis rs12497850 0.931 rs9682444 chr3:48852639 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs7647973 1.000 rs6783003 chr3:49524778 G/C cg06212747 chr3:49208901 KLHDC8B -0.59 -4.67 -0.39 7.6e-6 Menarche (age at onset); TGCT cis rs4642101 0.765 rs9870269 chr3:12853450 T/G cg05775895 chr3:12838266 CAND2 0.6 5.97 0.47 2.33e-8 QRS complex (12-leadsum); TGCT cis rs1865760 1.000 rs2071298 chr6:25914901 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.18 0.49 8.59e-9 Height; TGCT cis rs7772486 0.806 rs4075696 chr6:146250947 T/C cg05347473 chr6:146136440 FBXO30 -0.52 -5.16 -0.42 9.33e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9311474 0.713 rs352167 chr3:52238656 C/T cg10802521 chr3:52805072 NEK4 0.57 6.16 0.48 9.22e-9 Electroencephalogram traits; TGCT cis rs79349575 0.745 rs170319 chr17:46991531 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs4629710 0.592 rs35017713 chr6:131581212 G/A cg12606694 chr6:131520996 AKAP7 0.39 4.57 0.38 1.15e-5 Multiple myeloma (IgH translocation); TGCT cis rs61990749 0.597 rs2267761 chr14:78147849 G/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.69 -0.39 7.04e-6 Fibroblast growth factor basic levels; TGCT cis rs1008375 1.000 rs4698199 chr4:17656738 G/C cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.791 rs13111960 chr4:98976851 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.525 rs9611549 chr22:41705909 C/G cg06634786 chr22:41940651 POLR3H -0.61 -5.53 -0.44 1.8e-7 Vitiligo; TGCT cis rs17384381 1.000 rs12135333 chr1:85890494 C/A cg16011679 chr1:85725395 C1orf52 0.79 6.37 0.5 3.32e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7681440 0.874 rs7687945 chr4:90764699 C/T cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.82e-8 Dementia with Lewy bodies; TGCT trans rs4332037 0.950 rs10267593 chr7:1937261 G/A cg10840412 chr1:235813424 GNG4 0.92 7.25 0.55 3.83e-11 Bipolar disorder; TGCT cis rs7178572 0.568 rs7167794 chr15:77635875 T/C cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs1534166 0.602 rs3817524 chr3:133526403 C/T cg16414030 chr3:133502952 NA 0.41 5.15 0.42 1e-6 Alcohol consumption (transferrin glycosylation); TGCT cis rs10751667 0.621 rs7394681 chr11:952111 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs67311347 0.955 rs6599100 chr3:40447362 C/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT trans rs4650994 0.525 rs2493860 chr1:178541492 A/G cg05059571 chr16:84539110 KIAA1609 -0.54 -11.16 -0.71 1.91e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs5769765 1.000 rs8184990 chr22:50273174 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs73198271 0.740 rs28402110 chr8:8647249 C/A cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12220238 1.000 rs10824098 chr10:75943579 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1865760 1.000 rs9467636 chr6:25919549 A/C cg16482183 chr6:26056742 HIST1H1C 0.51 4.59 0.38 1.06e-5 Height; TGCT cis rs6951245 0.580 rs77101766 chr7:1122438 A/G cg18402987 chr7:1209562 NA 0.48 4.74 0.39 5.7e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs78366141 0.649 rs61737091 chr4:89671721 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.15 5.23 0.43 6.86e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs13392177 0.684 rs6720449 chr2:219080978 G/A cg00012203 chr2:219082015 ARPC2 -0.79 -8.02 -0.58 6.73e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs2050392 0.624 rs303447 chr10:30728464 T/C cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT cis rs11053548 0.602 rs12819440 chr12:10174884 A/C cg24820250 chr12:10084936 CLEC2A 0.26 4.65 0.39 8.33e-6 Systolic blood pressure in sickle cell anemia; TGCT cis rs7666738 0.515 rs11733968 chr4:98906448 A/C cg05340658 chr4:99064831 C4orf37 -0.57 -6.32 -0.49 4.36e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9393777 0.513 rs9348728 chr6:26634436 G/A cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.51 -4.68 -0.39 7.36e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.861 rs7526275 chr1:53245849 C/T cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs9322193 0.847 rs12234128 chr6:149948689 T/C cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs2050392 1.000 rs2480280 chr10:30696092 A/G cg18806716 chr10:30721971 MAP3K8 -0.44 -5.18 -0.42 8.82e-7 Inflammatory bowel disease; TGCT cis rs10056811 0.538 rs3923323 chr5:74372141 C/T cg19683494 chr5:74908142 NA -0.6 -4.74 -0.39 5.68e-6 Coronary artery disease; TGCT cis rs13256369 0.802 rs34762800 chr8:8559294 G/A cg18904891 chr8:8559673 CLDN23 0.57 5.04 0.41 1.6e-6 Obesity-related traits; TGCT cis rs174479 0.677 rs174463 chr11:61657838 G/A cg01500311 chr11:61656094 FADS3 0.28 5.03 0.41 1.68e-6 Sphingolipid levels; TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg21237687 chr17:6899380 ALOX12 0.51 5.47 0.44 2.39e-7 Tonsillectomy; TGCT cis rs7552404 0.727 rs7547508 chr1:76327958 A/G cg03433033 chr1:76189801 ACADM -0.59 -5.97 -0.47 2.34e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3733585 0.699 rs7663097 chr4:9966791 T/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.87 -0.58 1.53e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12049351 0.774 rs10799533 chr1:229656562 C/T cg12130225 chr1:229698885 NA 0.35 4.46 0.37 1.85e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs1372520 0.684 rs2583979 chr4:90750588 A/T cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs1862618 0.641 rs252893 chr5:56224714 T/C cg24531977 chr5:56204891 C5orf35 -0.68 -7.22 -0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs5750830 0.594 rs9611166 chr22:39775268 T/C cg01416388 chr22:39784598 NA -0.59 -5.8 -0.46 5.09e-8 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.808 rs6503515 chr17:37606433 G/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs4455778 0.600 rs56070219 chr7:49128237 A/T cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs9611565 0.559 rs132765 chr22:42008068 A/G cg03806693 chr22:41940476 POLR3H 1.07 11.4 0.72 4.95e-21 Vitiligo; TGCT cis rs4862307 0.688 rs6552741 chr4:184990335 A/G cg06737308 chr4:185021514 ENPP6 -0.38 -5.42 -0.44 2.95e-7 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs6684514 1.000 rs12134983 chr1:156290409 T/C cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6121246 0.529 rs73235789 chr20:30196148 T/C cg13852791 chr20:30311386 BCL2L1 0.7 4.68 0.39 7.29e-6 Mean corpuscular hemoglobin; TGCT cis rs7552404 0.855 rs385897 chr1:76106962 T/C cg10523679 chr1:76189770 ACADM -0.92 -10.1 -0.67 7.29e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1215050 0.791 rs2865943 chr4:98778449 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1046896 0.521 rs3859206 chr17:80693128 G/A cg00960700 chr17:80709150 TBCD 0.49 4.7 0.39 6.78e-6 Glycated hemoglobin levels; TGCT cis rs1511802 0.666 rs28698123 chr4:187123189 C/T cg19358738 chr4:186734530 SORBS2 0.18 4.57 0.38 1.16e-5 Blood protein levels; TGCT cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg06481639 chr22:41940642 POLR3H -0.73 -6.56 -0.51 1.32e-9 Vitiligo; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg22338127 chr1:209979572 IRF6 0.61 5.9 0.47 3.22e-8 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs2033711 0.870 rs1051500 chr19:58944402 A/G cg12042659 chr19:58951599 ZNF132 0.51 4.64 0.38 8.67e-6 Uric acid clearance; TGCT cis rs2299587 0.554 rs3853530 chr8:17748420 C/T cg04898035 chr8:17640624 MTUS1 -0.2 -4.63 -0.38 9.19e-6 Economic and political preferences; TGCT trans rs9388451 0.626 rs1739384 chr6:126099246 C/A cg05039488 chr6:79577232 IRAK1BP1 -0.8 -9.31 -0.64 5.94e-16 Brugada syndrome; TGCT cis rs2243480 1.000 rs13235972 chr7:65883605 C/T cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs71435601 0.689 rs34002646 chr2:21425323 A/G cg25035485 chr2:21266500 APOB -0.55 -4.68 -0.39 7.46e-6 Cholesterol, total; TGCT cis rs7191439 0.858 rs2290902 chr16:88782676 A/G cg27087555 chr16:88793112 FAM38A -0.45 -5.0 -0.41 1.91e-6 Plateletcrit; TGCT cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.549 rs34160989 chr21:40554118 C/G cg11644478 chr21:40555479 PSMG1 0.83 6.1 0.48 1.23e-8 Cognitive function; TGCT cis rs1799949 0.894 rs36062488 chr17:41337472 C/T cg23758822 chr17:41437982 NA -0.68 -6.79 -0.52 4.2e-10 Menopause (age at onset); TGCT cis rs2456568 0.835 rs8181533 chr11:93638614 C/T cg14065697 chr11:93583672 C11orf90 -0.38 -4.74 -0.39 5.65e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs860295 0.557 rs6696019 chr1:155864977 T/C cg13795986 chr1:155880507 RIT1 0.38 4.61 0.38 9.9e-6 Body mass index; TGCT cis rs2288278 0.601 rs925284 chr17:46585890 A/G cg25032089 chr17:46643351 HOXB3 -0.42 -5.03 -0.41 1.68e-6 Hand grip strength; TGCT cis rs7666738 0.546 rs28590002 chr4:98722642 C/T cg17366294 chr4:99064904 C4orf37 0.61 5.68 0.45 9.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs77741769 0.571 rs12371178 chr12:121309129 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs4253772 0.637 rs7284687 chr22:46690321 T/C cg24881330 chr22:46731750 TRMU 1.03 5.67 0.45 9.45e-8 LDL cholesterol;Cholesterol, total; TGCT cis rs12989701 0.877 rs34745987 chr2:127875384 C/T cg08168897 chr2:127865431 BIN1 0.53 5.77 0.46 6.05e-8 Alzheimer's disease (late onset); TGCT cis rs7267979 0.718 rs2983489 chr20:25244120 C/A cg14121845 chr20:25566513 NINL 0.45 4.8 0.4 4.44e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9534288 0.699 rs2146885 chr13:46659853 A/G cg15192986 chr13:46630673 CPB2 -0.53 -6.39 -0.5 3.01e-9 Blood protein levels; TGCT cis rs10875746 0.669 rs11168496 chr12:48650855 G/A cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT cis rs4366490 0.665 rs2105623 chr11:62904168 A/C cg21002970 chr11:62369079 MTA2 0.87 4.67 0.39 7.78e-6 Conotruncal heart defects; TGCT cis rs6921919 0.583 rs12697938 chr6:28341099 T/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.37 -0.43 3.8e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs7255045 0.664 rs4614850 chr19:12974636 G/T cg23899408 chr19:12877188 HOOK2 -0.61 -4.99 -0.41 1.97e-6 Mean corpuscular volume; TGCT cis rs3785574 0.650 rs2070776 chr17:62007498 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -1.0 -11.14 -0.71 2.13e-20 Height; TGCT cis rs9581857 0.556 rs1885990 chr13:28040502 C/T cg22138327 chr13:27999177 GTF3A 0.71 5.65 0.45 1.05e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.15e-6 Blood metabolite levels; TGCT cis rs763014 0.932 rs7204439 chr16:661335 T/C cg00908189 chr16:619842 PIGQ 0.85 10.29 0.68 2.43e-18 Height; TGCT cis rs7647973 0.626 rs1996664 chr3:49878395 A/G cg03060546 chr3:49711283 APEH -0.62 -5.56 -0.45 1.59e-7 Menarche (age at onset); TGCT cis rs12472274 0.817 rs34791859 chr2:239070919 G/C cg17459225 chr2:239074497 NA 0.32 4.79 0.4 4.65e-6 Phospholipid levels (plasma); TGCT cis rs7937682 0.564 rs4938723 chr11:111382565 T/C cg09085632 chr11:111637200 PPP2R1B 0.56 4.95 0.41 2.42e-6 Primary sclerosing cholangitis; TGCT cis rs2836950 0.565 rs8134214 chr21:40542367 A/C cg11644478 chr21:40555479 PSMG1 -0.51 -4.68 -0.39 7.41e-6 Menarche (age at onset); TGCT cis rs478304 0.654 rs1074156 chr11:65458169 G/T cg27068330 chr11:65405492 SIPA1 -1.04 -10.95 -0.7 6.22e-20 Acne (severe); TGCT cis rs2797160 1.000 rs1739373 chr6:126011509 A/G cg05901451 chr6:126070800 HEY2 0.75 6.33 0.49 4.14e-9 Endometrial cancer; TGCT cis rs10056811 0.538 rs4632781 chr5:74376658 G/C cg19683494 chr5:74908142 NA 0.63 5.06 0.41 1.49e-6 Coronary artery disease; TGCT cis rs8177253 1.000 rs6439439 chr3:133481498 G/T cg08439880 chr3:133502540 NA -0.31 -5.87 -0.47 3.69e-8 Iron status biomarkers; TGCT cis rs9733 0.596 rs2867300 chr1:150666990 C/G cg04414720 chr1:150670196 GOLPH3L 0.38 4.99 0.41 2e-6 Tonsillectomy; TGCT cis rs6121246 0.512 rs6060938 chr20:30363645 T/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs7208859 0.623 rs7220999 chr17:29149298 C/T cg14008862 chr17:28927542 LRRC37B2 0.8 4.73 0.39 6.11e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs783396 0.642 rs9486402 chr6:107014250 C/G cg09256880 chr4:2791952 NA 0.49 6.77 0.52 4.5e-10 Stroke; TGCT cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs2204008 0.542 rs34770471 chr12:38009613 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs35306767 0.903 rs12769431 chr10:922633 T/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs2996428 0.667 rs7511793 chr1:3744249 A/G cg17848003 chr1:3704513 LRRC47 0.19 5.21 0.42 7.56e-7 Red cell distribution width; TGCT cis rs9611565 0.573 rs9306355 chr22:42111896 A/T cg06634786 chr22:41940651 POLR3H 0.82 7.9 0.58 1.3e-12 Vitiligo; TGCT cis rs9807989 0.765 rs9807962 chr2:102971664 A/G cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs9372253 1.000 rs9372253 chr6:110716136 C/T cg13266496 chr6:110720918 DDO -0.46 -5.68 -0.45 8.89e-8 Platelet distribution width; TGCT cis rs10986311 0.681 rs10818937 chr9:127015440 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.65 -0.39 8.32e-6 Vitiligo; TGCT cis rs4901869 0.932 rs12878445 chr14:59339361 A/G cg02291164 chr14:59296302 NA 0.24 4.7 0.39 6.86e-6 Panic disorder; TGCT cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg12311346 chr5:56204834 C5orf35 -0.63 -6.36 -0.5 3.5e-9 Initial pursuit acceleration; TGCT cis rs1784581 0.608 rs1784603 chr6:162370272 G/A cg17173639 chr6:162384350 PARK2 -0.42 -7.3 -0.55 3.07e-11 Itch intensity from mosquito bite; TGCT cis rs425277 1.000 rs262670 chr1:2082458 C/T cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT cis rs2072499 0.900 rs2248080 chr1:156195971 T/A cg24450063 chr1:156163899 SLC25A44 1.18 13.63 0.77 1.99e-26 Testicular germ cell tumor; TGCT cis rs61867294 0.761 rs7085496 chr10:106699212 A/G cg08000847 chr10:105880925 C10orf78 -0.54 -4.46 -0.37 1.81e-5 Schizophrenia; TGCT cis rs10858047 0.883 rs7555301 chr1:115199930 G/A cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs7843479 0.582 rs11779655 chr8:21794041 A/G cg17168535 chr8:21777572 XPO7 -0.81 -8.33 -0.6 1.25e-13 Mean corpuscular volume; TGCT cis rs10936602 0.527 rs9882101 chr3:169548655 G/A cg08193579 chr3:169529701 LRRC34 0.28 5.07 0.41 1.39e-6 Renal cell carcinoma; TGCT cis rs7547997 0.685 rs7521814 chr1:158346996 G/A cg07950803 chr1:158223934 CD1A 0.32 4.78 0.39 4.95e-6 QRS duration; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg02953382 chr22:24373134 LOC391322 -0.78 -8.12 -0.59 4.06e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs644799 1.000 rs1784135 chr11:95531748 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4665809 1.000 rs6546766 chr2:26328680 T/C cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs2730245 0.592 rs2657385 chr7:158649373 A/G cg11984989 chr7:158649758 WDR60 1.06 9.85 0.66 2.94e-17 Height; TGCT cis rs7267979 0.789 rs6050472 chr20:25219852 A/G cg03522245 chr20:25566470 NINL 0.53 5.26 0.43 6.04e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7804356 0.651 rs55959127 chr7:26810146 C/T cg03456212 chr7:26904342 SKAP2 -0.54 -4.6 -0.38 1.04e-5 Type 1 diabetes; TGCT cis rs611744 0.967 rs651814 chr8:109196571 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs1541995 0.789 rs71396825 chr15:96236915 G/C cg00882281 chr15:96346592 NA 0.3 4.63 0.38 9.12e-6 Photic sneeze reflex; TGCT cis rs6424115 0.830 rs1106 chr1:24200772 C/G cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs4862750 0.872 rs4862748 chr4:187877388 C/T cg10295955 chr4:187884368 NA 1.01 13.56 0.77 3.07e-26 Lobe attachment (rater-scored or self-reported); TGCT cis rs6426558 0.621 rs7521639 chr1:227223736 T/C cg10327440 chr1:227177885 CDC42BPA 0.68 8.74 0.62 1.38e-14 Neutrophil percentage of white cells; TGCT cis rs3806843 0.898 rs3756335 chr5:140213510 A/T cg19875535 chr5:140030758 IK 0.37 6.06 0.48 1.54e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9308731 0.787 rs13388990 chr2:111862303 T/C cg04202892 chr2:111875749 ACOXL 0.44 4.46 0.37 1.79e-5 Chronic lymphocytic leukemia; TGCT cis rs9399137 0.507 rs4580893 chr6:135297662 G/A cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs76878669 0.561 rs7115577 chr11:66172258 G/T cg18002602 chr11:66138449 SLC29A2 -0.52 -6.31 -0.49 4.48e-9 Educational attainment (years of education); TGCT cis rs6840360 0.571 rs7678080 chr4:152557350 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs6484504 0.576 rs208067 chr11:31153578 C/T cg26647111 chr11:31128758 NA -0.33 -4.55 -0.38 1.27e-5 Red blood cell count; TGCT cis rs11098499 0.644 rs34835603 chr4:120553428 C/T cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs28595532 0.920 rs17259284 chr4:119779298 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs72781680 0.821 rs111571980 chr2:24201695 C/G cg08917208 chr2:24149416 ATAD2B 0.72 4.5 0.37 1.56e-5 Lymphocyte counts; TGCT cis rs877282 0.945 rs10904556 chr10:789429 A/G cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs9473924 0.505 rs4111288 chr6:50908094 G/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs9522267 0.535 rs4644738 chr13:112235995 G/A cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs12908161 0.960 rs34452033 chr15:85221993 A/G cg12863693 chr15:85201151 NMB 0.46 5.53 0.44 1.79e-7 Schizophrenia; TGCT cis rs12908161 1.000 rs11632465 chr15:85282045 A/T cg12863693 chr15:85201151 NMB 0.42 4.99 0.41 2.03e-6 Schizophrenia; TGCT cis rs514406 0.861 rs4926576 chr1:53226775 C/T cg08859206 chr1:53392774 SCP2 0.4 5.97 0.47 2.38e-8 Monocyte count; TGCT cis rs12971120 0.891 rs12605820 chr18:72167802 G/A cg26446133 chr18:72167187 CNDP2 -0.36 -6.11 -0.48 1.2e-8 Refractive error; TGCT cis rs11696501 0.739 rs6017637 chr20:44264190 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.58 -0.38 1.14e-5 Brain structure; TGCT cis rs11690935 0.571 rs13020884 chr2:172901699 T/G cg13550731 chr2:172543902 DYNC1I2 0.64 5.83 0.46 4.45e-8 Schizophrenia; TGCT cis rs9926296 0.682 rs258328 chr16:89730314 C/T cg21285383 chr16:89894308 SPIRE2 -0.32 -4.52 -0.38 1.42e-5 Vitiligo; TGCT cis rs7172809 0.643 rs4886874 chr15:77838086 A/C cg22256960 chr15:77711686 NA 0.49 5.0 0.41 1.91e-6 Glucose homeostasis traits; TGCT cis rs7474896 0.583 rs12783272 chr10:38024885 T/G cg13720705 chr10:37990370 NA 0.39 5.53 0.44 1.83e-7 Obesity (extreme); TGCT cis rs2239547 0.563 rs6797399 chr3:52905917 G/A cg11645453 chr3:52864694 ITIH4 0.34 5.72 0.46 7.68e-8 Schizophrenia; TGCT cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg00684032 chr4:1343700 KIAA1530 -0.22 -4.71 -0.39 6.65e-6 Obesity-related traits; TGCT cis rs11578119 0.933 rs12116910 chr1:170465981 A/T cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs11122272 0.735 rs2808604 chr1:231538916 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs244731 0.919 rs12652509 chr5:176626441 A/G cg17509989 chr5:176798049 RGS14 -0.6 -7.32 -0.55 2.69e-11 Urate levels in lean individuals; TGCT cis rs11098499 0.913 rs11098496 chr4:120167466 C/G cg24670566 chr4:120433619 PDE5A 0.23 4.58 0.38 1.13e-5 Corneal astigmatism; TGCT cis rs2836974 0.568 rs11910906 chr21:40685662 T/C cg11644478 chr21:40555479 PSMG1 -0.58 -5.1 -0.42 1.23e-6 Cognitive function; TGCT cis rs6088590 1.000 rs1998028 chr20:33344595 A/T cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT cis rs11614913 0.551 rs1867297 chr12:54396971 A/G cg03037150 chr12:54402717 HOXC8 -0.59 -5.03 -0.41 1.69e-6 Waist circumference adjusted for body mass index; TGCT cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs10949834 0.504 rs77541100 chr7:73555605 C/T cg07137043 chr7:73588983 EIF4H -0.68 -4.71 -0.39 6.54e-6 Verbal memory performance (residualized delayed recall change); TGCT cis rs45509595 0.841 rs9368531 chr6:27781872 G/C cg10876282 chr6:28092338 ZSCAN16 0.78 4.57 0.38 1.17e-5 Breast cancer; TGCT cis rs910316 0.935 rs175422 chr14:75627319 T/A cg11812906 chr14:75593930 NEK9 -0.73 -7.21 -0.54 4.87e-11 Height; TGCT cis rs478304 0.651 rs4930313 chr11:65500428 C/T cg27068330 chr11:65405492 SIPA1 -0.94 -9.4 -0.65 3.49e-16 Acne (severe); TGCT cis rs172166 0.585 rs149963 chr6:28017132 G/A cg13525197 chr6:28411240 ZSCAN23 -0.46 -4.49 -0.37 1.58e-5 Cardiac Troponin-T levels; TGCT cis rs35306767 0.669 rs2101051 chr10:1158791 G/T cg20503657 chr10:835505 NA 0.54 5.77 0.46 6.01e-8 Eosinophil percentage of granulocytes; TGCT cis rs11112613 0.713 rs12316204 chr12:105944244 G/A cg03607813 chr12:105948248 NA 0.48 5.5 0.44 2.04e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs9633740 0.947 rs7096909 chr10:82284512 A/T cg01528321 chr10:82214614 TSPAN14 -0.98 -7.99 -0.58 7.94e-13 Post bronchodilator FEV1; TGCT cis rs2153535 0.505 rs1737583 chr6:8536812 G/A cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs79349575 0.783 rs58591767 chr17:47026076 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs10754283 0.871 rs72712569 chr1:90125657 G/C cg03145924 chr1:90228473 NA 0.37 4.46 0.37 1.85e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6912958 0.559 rs242281 chr6:88048916 A/C cg04972856 chr6:88032051 C6orf162;GJB7 0.4 4.71 0.39 6.65e-6 Monocyte percentage of white cells; TGCT cis rs8032315 0.965 rs1894400 chr15:91428955 C/T cg06330618 chr15:91428456 FES 0.19 4.8 0.4 4.4e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7394190 0.748 rs2306327 chr10:75573778 A/T cg07699608 chr10:75541558 CHCHD1 0.81 5.6 0.45 1.33e-7 Incident atrial fibrillation; TGCT cis rs11031096 0.754 rs10835611 chr11:4117730 G/C cg18678763 chr11:4115507 RRM1 -0.43 -5.48 -0.44 2.31e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7772486 0.686 rs1292336 chr6:145967818 T/C cg23711669 chr6:146136114 FBXO30 -0.81 -8.79 -0.62 1.03e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs9677476 0.657 rs13418346 chr2:232132374 A/G cg07929768 chr2:232055508 NA -0.32 -5.06 -0.41 1.45e-6 Food antigen IgG levels; TGCT cis rs9419702 0.614 rs9419567 chr10:133535149 C/G cg04492858 chr10:133558786 NA 0.53 5.74 0.46 6.85e-8 Survival in rectal cancer; TGCT cis rs11098499 0.866 rs6824111 chr4:120285968 T/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs7666738 0.830 rs1349757 chr4:99058763 C/G cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg03264133 chr6:25882463 NA -0.71 -6.7 -0.52 6.62e-10 Intelligence (multi-trait analysis); TGCT cis rs13191362 1.000 rs66534429 chr6:163003322 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7027203 0.828 rs10761288 chr9:96609363 C/T cg13679303 chr9:96623674 NA -0.63 -9.61 -0.65 1.11e-16 DNA methylation (variation); TGCT cis rs4722166 0.695 rs4722177 chr7:22798531 T/C cg26061582 chr7:22766209 IL6 0.48 6.25 0.49 6.15e-9 Lung cancer; TGCT cis rs5760092 0.572 rs738806 chr22:24234172 A/G cg00024416 chr22:24240387 NA -0.32 -5.56 -0.45 1.6e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs12478296 1.000 rs60533128 chr2:243028088 A/G cg06360820 chr2:242988706 NA -0.85 -5.6 -0.45 1.3e-7 Obesity-related traits; TGCT cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg20203395 chr5:56204925 C5orf35 -0.56 -4.8 -0.4 4.39e-6 Initial pursuit acceleration; TGCT cis rs8033133 0.958 rs6420956 chr15:25309559 T/C cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.26 -4.73 -0.39 6.13e-6 Blood osmolality (transformed sodium); TGCT cis rs2652822 0.509 rs6494394 chr15:63440938 A/G cg12855773 chr15:63363890 TPM1 -0.19 -5.01 -0.41 1.85e-6 Metabolic traits; TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs1018836 0.669 rs6471243 chr8:91656967 C/T cg16814680 chr8:91681699 NA 0.96 13.2 0.76 2.18e-25 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs968451 0.789 rs11089939 chr22:39680957 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.81 7.97 0.58 8.95e-13 Primary biliary cholangitis; TGCT cis rs8064299 0.597 rs4789097 chr17:72781208 C/T cg25054828 chr17:72772726 NAT9;TMEM104 -0.9 -10.32 -0.68 2.06e-18 Monocyte count; TGCT cis rs10435719 0.902 rs7014580 chr8:11803262 C/G cg02840367 chr8:11660030 FDFT1 -0.52 -4.48 -0.37 1.7e-5 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs13424612 1.000 rs66534347 chr2:240899346 G/A cg26363272 chr2:240904871 NDUFA10 0.31 5.19 0.42 8.3e-7 Odorant perception (isobutyraldehyde); TGCT cis rs9427116 0.875 rs11264233 chr1:154625632 C/T cg17218026 chr1:154582156 ADAR 0.26 6.24 0.49 6.39e-9 Blood protein levels; TGCT cis rs2180341 0.782 rs6912552 chr6:127722946 C/G cg27446573 chr6:127587934 RNF146 -0.78 -6.82 -0.52 3.47e-10 Breast cancer; TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg07167872 chr1:205819463 PM20D1 -0.53 -6.88 -0.53 2.6e-10 Monocyte percentage of white cells; TGCT cis rs12220898 0.679 rs10776555 chr10:50484995 A/G cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg23103009 chr10:134564232 INPP5A 0.28 4.44 0.37 1.94e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7336332 0.598 rs1885988 chr13:28010262 C/T cg22138327 chr13:27999177 GTF3A -0.77 -6.2 -0.49 7.87e-9 Weight; TGCT cis rs6582630 0.519 rs11514372 chr12:38308613 T/G cg13010199 chr12:38710504 ALG10B 0.57 4.49 0.37 1.62e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs4704846 1.000 rs1036199 chr5:156531736 C/A cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs12579753 0.871 rs4255611 chr12:82215969 C/A cg07988820 chr12:82153109 PPFIA2 -0.58 -6.06 -0.48 1.52e-8 Resting heart rate; TGCT cis rs2549003 1.000 rs2706384 chr5:131826880 G/T cg02551604 chr5:131831745 NA 0.9 11.87 0.73 3.59e-22 Asthma (sex interaction); TGCT cis rs11098499 0.863 rs6858592 chr4:120458692 G/A cg09307838 chr4:120376055 NA 0.71 6.96 0.53 1.71e-10 Corneal astigmatism; TGCT cis rs611744 0.647 rs676654 chr8:109242303 A/G cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.44e-11 Dupuytren's disease; TGCT cis rs10791323 0.575 rs4489760 chr11:133732265 A/T cg03690763 chr11:133734501 NA -0.28 -4.44 -0.37 1.96e-5 Childhood ear infection; TGCT cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10504229 0.679 rs16921676 chr8:58052386 G/T cg08280861 chr8:58055591 NA 0.39 5.61 0.45 1.28e-7 Developmental language disorder (linguistic errors); TGCT cis rs2594989 0.831 rs2443703 chr3:11564191 C/T cg00170343 chr3:11313890 ATG7 -0.72 -5.09 -0.42 1.27e-6 Circulating chemerin levels; TGCT cis rs244731 0.959 rs4976677 chr5:176629546 G/A cg17509989 chr5:176798049 RGS14 -0.6 -7.32 -0.55 2.69e-11 Urate levels in lean individuals; TGCT cis rs8016982 0.611 rs8008870 chr14:81709374 C/T cg01989461 chr14:81687754 GTF2A1 0.78 7.8 0.57 2.21e-12 Schizophrenia; TGCT cis rs4499344 0.633 rs259262 chr19:33153951 G/A cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT cis rs4389656 0.767 rs274704 chr5:6728340 A/G cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs7666738 0.606 rs7663216 chr4:99088385 A/C cg05340658 chr4:99064831 C4orf37 0.44 4.72 0.39 6.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4862750 0.914 rs6837117 chr4:187872379 C/T cg10295955 chr4:187884368 NA -0.93 -12.52 -0.75 9.29e-24 Lobe attachment (rater-scored or self-reported); TGCT cis rs8013055 0.846 rs10151805 chr14:105974781 T/C cg19700328 chr14:106028568 NA -0.53 -5.91 -0.47 3.03e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs12142240 0.845 rs4313342 chr1:46801904 T/C cg14993813 chr1:46806288 NSUN4 -0.54 -4.51 -0.38 1.46e-5 Menopause (age at onset); TGCT cis rs1453308 1.000 rs6713580 chr2:237184230 T/C cg19324714 chr2:237145437 ASB18 0.58 5.13 0.42 1.11e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs8067545 1.000 rs3909258 chr17:19945819 C/G cg13482628 chr17:19912719 NA 0.53 4.48 0.37 1.66e-5 Schizophrenia; TGCT cis rs797680 0.856 rs602204 chr1:93727579 A/G cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6951245 0.554 rs4724294 chr7:1139695 G/A cg18402987 chr7:1209562 NA 0.48 4.79 0.39 4.72e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs1814175 0.511 rs61905634 chr11:49819736 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs4820539 1.000 rs2267002 chr22:23456702 T/C cg14186256 chr22:23484241 RTDR1 0.99 12.18 0.74 6.44e-23 Bone mineral density; TGCT cis rs1801251 0.778 rs2675957 chr2:233754364 C/T cg25237894 chr2:233734115 C2orf82 -0.3 -5.75 -0.46 6.52e-8 Coronary artery disease; TGCT cis rs10838634 0.901 rs12281784 chr11:46908250 C/T cg18332754 chr11:46939436 LRP4 0.87 4.48 0.37 1.68e-5 Schizophrenia; TGCT cis rs2455799 0.613 rs1345157 chr3:15895581 C/G cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.63e-6 Mean platelet volume; TGCT cis rs10509586 1.000 rs17504192 chr10:91783041 C/A cg25278353 chr10:91717815 NA 0.48 4.53 0.38 1.34e-5 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs35146811 0.731 rs2257213 chr7:99810113 T/C cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs875971 0.800 rs427557 chr7:65519250 A/G cg11764359 chr7:65958608 NA 0.54 4.66 0.39 7.88e-6 Aortic root size; TGCT cis rs10779751 0.734 rs2791648 chr1:11132638 G/T cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs941873 0.772 rs1316312 chr10:81110417 G/C cg09469691 chr10:81107165 PPIF 0.51 5.03 0.41 1.69e-6 Height; TGCT cis rs7772486 0.875 rs6938972 chr6:146410608 G/A cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1215050 0.791 rs1605259 chr4:98799732 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs5769765 0.908 rs138880 chr22:50218611 A/C cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.66 0.45 9.92e-8 Schizophrenia; TGCT cis rs1371867 0.875 rs1788173 chr8:101330939 A/G cg00191853 chr8:101177733 SPAG1 0.22 4.71 0.39 6.63e-6 Atrioventricular conduction; TGCT cis rs7666738 0.830 rs10470951 chr4:99037051 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9916302 0.904 rs8079560 chr17:37497661 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs4372836 0.729 rs12475612 chr2:29030006 T/G cg09522027 chr2:28974177 PPP1CB 0.65 6.65 0.51 8.32e-10 Body mass index; TGCT cis rs7647973 1.000 rs11928090 chr3:49604904 G/A cg07636037 chr3:49044803 WDR6 0.6 4.96 0.41 2.22e-6 Menarche (age at onset); TGCT cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg23719950 chr11:63933701 MACROD1 -0.72 -5.92 -0.47 2.99e-8 Mean platelet volume; TGCT cis rs17030434 0.654 rs1530105 chr4:154646994 C/T cg14289246 chr4:154710475 SFRP2 0.74 5.53 0.44 1.84e-7 Electrocardiographic conduction measures; TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg27535305 chr1:53392650 SCP2 -0.27 -5.45 -0.44 2.58e-7 Monocyte count; TGCT cis rs13102973 0.682 rs13107817 chr4:135885535 C/T cg14419869 chr4:135874104 NA 0.26 4.55 0.38 1.28e-5 Subjective well-being; TGCT cis rs6460942 0.908 rs77894875 chr7:12248257 T/C cg06484146 chr7:12443880 VWDE -0.58 -4.81 -0.4 4.32e-6 Coronary artery disease; TGCT cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs2439831 0.867 rs2927072 chr15:43922398 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.61 0.51 1.03e-9 Lung cancer in ever smokers; TGCT cis rs6459788 0.692 rs10807645 chr7:157258979 T/C cg06271696 chr7:157225062 NA 0.27 5.02 0.41 1.77e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7208859 0.623 rs9898084 chr17:29082334 C/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7917772 0.636 rs4919676 chr10:104524352 C/T cg05855489 chr10:104503620 C10orf26 0.67 5.32 0.43 4.77e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs896854 0.967 rs896853 chr8:95960855 G/C cg16049864 chr8:95962084 TP53INP1 -0.77 -11.3 -0.71 8.62e-21 Type 2 diabetes; TGCT cis rs1215050 0.791 rs260899 chr4:98707046 G/A cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs977747 0.836 rs4926521 chr1:47674769 G/A cg03885399 chr1:47691550 TAL1 -0.42 -5.48 -0.44 2.26e-7 Body mass index; TGCT cis rs78245978 0.744 rs7080622 chr10:2637022 A/C cg17670436 chr10:3374199 NA 0.55 4.95 0.41 2.4e-6 Major depressive disorder; TGCT cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs6089829 0.962 rs6122350 chr20:61664617 A/G cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs11098499 0.874 rs28452522 chr4:120110784 A/G cg09307838 chr4:120376055 NA 0.5 4.61 0.38 1e-5 Corneal astigmatism; TGCT cis rs7647973 0.580 rs7652746 chr3:49262307 C/T cg02487422 chr3:49467188 NICN1 -0.53 -5.15 -0.42 9.76e-7 Menarche (age at onset); TGCT cis rs6089584 1.000 rs6089580 chr20:60558976 G/A cg13770153 chr20:60521292 NA -0.44 -5.62 -0.45 1.21e-7 Body mass index; TGCT cis rs9902453 1.000 rs60967688 chr17:28437052 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.71 6.09 0.48 1.28e-8 Coffee consumption (cups per day); TGCT cis rs7582180 0.663 rs4850929 chr2:100990707 A/C cg14675211 chr2:100938903 LONRF2 0.48 4.6 0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT cis rs769267 0.930 rs1054930 chr19:19648346 G/C cg03709012 chr19:19516395 GATAD2A 0.74 6.04 0.48 1.65e-8 Tonsillectomy; TGCT cis rs854765 0.583 rs4077198 chr17:17834563 T/C cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs12510870 0.599 rs2141470 chr4:74385090 T/C cg05868023 chr4:75230803 EREG 0.56 5.07 0.41 1.42e-6 Iris color (b* coordinate); TGCT cis rs3806843 0.801 rs801170 chr5:140115343 C/T cg19875535 chr5:140030758 IK -0.35 -5.94 -0.47 2.63e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs832540 0.902 rs194059 chr5:56197416 G/A cg24531977 chr5:56204891 C5orf35 -0.52 -5.23 -0.43 6.85e-7 Coronary artery disease; TGCT cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg13683864 chr3:40499215 RPL14 -1.12 -11.8 -0.73 5.17e-22 Renal cell carcinoma; TGCT cis rs1153858 1.000 rs59889118 chr15:45618730 G/A cg14582100 chr15:45693742 SPATA5L1 0.52 6.13 0.48 1.09e-8 Homoarginine levels; TGCT cis rs7208859 0.673 rs2269915 chr17:29233344 C/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs6762477 0.748 rs3755831 chr3:50228767 G/T cg21659725 chr3:3221576 CRBN -0.68 -7.49 -0.56 1.12e-11 Menarche (age at onset); TGCT trans rs4332037 0.950 rs7807014 chr7:1939021 T/C cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs4733781 1.000 rs876575 chr8:131210851 A/G cg16277922 chr8:131349729 ASAP1 0.44 5.73 0.46 7.33e-8 Tuberculosis; TGCT cis rs9894429 0.608 rs7406219 chr17:79609410 G/T cg21028142 chr17:79581711 NPLOC4 0.29 5.95 0.47 2.56e-8 Eye color traits; TGCT cis rs13191362 1.000 rs34443622 chr6:163208214 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.09 7.16 0.54 6.36e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10779751 0.734 rs2791653 chr1:11129848 A/G cg08854313 chr1:11322531 MTOR 0.85 6.96 0.53 1.74e-10 Body mass index; TGCT cis rs35306767 0.855 rs12771179 chr10:872347 A/G cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs7666738 0.716 rs11097615 chr4:99092773 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.04 0.41 1.58e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10170846 0.861 rs7571732 chr2:223538316 A/C cg25565276 chr2:223520875 FARSB -0.55 -4.58 -0.38 1.1e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs7302981 0.967 rs7136570 chr12:50529936 A/G cg23855989 chr12:50355821 AQP5 -0.3 -4.44 -0.37 2e-5 Systolic blood pressure; TGCT cis rs6879260 0.928 rs11739624 chr5:179727290 T/C cg23221052 chr5:179740743 GFPT2 -0.33 -5.09 -0.42 1.27e-6 Height; TGCT cis rs889312 0.500 rs252903 chr5:56117952 A/G cg24531977 chr5:56204891 C5orf35 -0.53 -5.5 -0.44 2.07e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs11190604 1.000 rs2495750 chr10:102327708 A/G cg16342193 chr10:102329863 NA -0.42 -5.39 -0.44 3.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1691799 0.899 rs1168301 chr12:66736771 C/T cg16791601 chr12:66731901 HELB -0.27 -5.99 -0.47 2.14e-8 White blood cell count (basophil); TGCT cis rs17511627 0.799 rs2900999 chr13:26732244 C/T cg20241335 chr13:25876335 NUPL1 0.7 4.54 0.38 1.33e-5 Alzheimer's disease; TGCT cis rs10256972 0.900 rs7812072 chr7:1053862 A/G cg16145915 chr7:1198662 ZFAND2A -0.39 -4.61 -0.38 1e-5 Longevity;Endometriosis; TGCT trans rs7618501 0.521 rs2883059 chr3:49902160 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.89 -9.57 -0.65 1.42e-16 Intelligence (multi-trait analysis); TGCT cis rs274567 0.602 rs272853 chr5:131688561 A/G cg18758796 chr5:131593413 PDLIM4 0.43 4.77 0.39 5.02e-6 Blood metabolite levels; TGCT cis rs9341808 0.727 rs9361599 chr6:81025242 C/G cg08355045 chr6:80787529 NA 0.28 4.74 0.39 5.73e-6 Sitting height ratio; TGCT cis rs7674212 0.537 rs2623060 chr4:104047504 G/A cg16532752 chr4:104119610 CENPE -0.64 -5.86 -0.47 3.95e-8 Type 2 diabetes; TGCT cis rs17767294 0.614 rs72850302 chr6:28241398 A/G cg08851530 chr6:28072375 NA 1.54 6.89 0.53 2.51e-10 Parkinson's disease; TGCT cis rs910187 0.605 rs2281367 chr20:45808960 T/C cg27589058 chr20:45804311 EYA2 -0.4 -9.01 -0.63 3.13e-15 Migraine; TGCT cis rs7824557 0.679 rs13279067 chr8:11135828 A/G cg21775007 chr8:11205619 TDH -0.59 -5.45 -0.44 2.6e-7 Retinal vascular caliber; TGCT cis rs1729951 0.575 rs361243 chr3:136697786 C/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.62e-9 Neuroticism; TGCT cis rs1799949 1.000 rs4793197 chr17:41231902 C/T cg10047753 chr17:41438598 NA 0.96 9.86 0.66 2.71e-17 Menopause (age at onset); TGCT cis rs2486288 0.554 rs1719235 chr15:45576108 A/G cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.36 -0.43 3.89e-7 Glomerular filtration rate; TGCT cis rs72781680 1.000 rs72788286 chr2:24098321 A/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs6087990 0.899 rs4911110 chr20:31392366 C/T cg13636640 chr20:31349939 DNMT3B -1.01 -14.85 -0.8 2.7e-29 Ulcerative colitis; TGCT cis rs7937682 0.663 rs3867466 chr11:111668256 A/C cg09085632 chr11:111637200 PPP2R1B 0.79 6.54 0.51 1.45e-9 Primary sclerosing cholangitis; TGCT cis rs7666738 0.830 rs13116691 chr4:98929771 A/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9322193 1.000 rs9377228 chr6:149921998 G/A cg13206674 chr6:150067644 NUP43 0.51 4.47 0.37 1.76e-5 Lung cancer; TGCT cis rs8102476 0.846 rs11083450 chr19:38754239 T/C cg14131526 chr19:38747285 PPP1R14A -0.53 -4.63 -0.38 8.98e-6 Prostate cancer;Prostate cancer (SNP x SNP interaction); TGCT cis rs7954584 0.813 rs11043288 chr12:122451187 C/T cg21016266 chr12:122356598 WDR66 -0.41 -5.12 -0.42 1.13e-6 Mean corpuscular volume; TGCT cis rs9302001 0.920 rs4773819 chr13:95456973 T/C cg07483244 chr13:95358924 NA 0.37 4.8 0.4 4.42e-6 Panic disorder; TGCT cis rs698813 0.604 rs11676798 chr2:44479982 G/C cg00619915 chr2:44497795 NA -0.24 -5.62 -0.45 1.19e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs362296 0.698 rs362279 chr4:3260072 G/A cg06533319 chr4:3265114 C4orf44 0.24 4.52 0.38 1.4e-5 Parental longevity (mother's age at death); TGCT cis rs7666738 0.830 rs4502686 chr4:98765117 T/C cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7917772 0.636 rs2249850 chr10:104512006 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.66 5.42 0.44 2.94e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.830 rs13139024 chr4:99020700 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg21724239 chr8:58056113 NA 0.4 4.91 0.4 2.75e-6 Developmental language disorder (linguistic errors); TGCT cis rs72781680 0.752 rs72796138 chr2:23926233 C/T cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT cis rs425277 0.606 rs2503705 chr1:2076741 A/G cg24578937 chr1:2090814 PRKCZ 0.24 5.81 0.46 4.87e-8 Height; TGCT cis rs514406 0.825 rs3863643 chr1:53224577 C/T cg01802117 chr1:53393560 SCP2 0.43 5.13 0.42 1.1e-6 Monocyte count; TGCT cis rs2439831 1.000 rs690316 chr15:43737880 C/A cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.42 0.6 7.81e-14 Lung cancer in ever smokers; TGCT cis rs7772486 0.754 rs6932863 chr6:146021255 A/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg23758822 chr17:41437982 NA 0.68 6.26 0.49 5.76e-9 Menopause (age at onset); TGCT cis rs2562456 0.617 rs34203148 chr19:21773545 T/A cg13978929 chr19:21580086 ZNF493 -0.55 -4.69 -0.39 7.04e-6 Pain; TGCT cis rs7208859 0.524 rs59923796 chr17:29064919 G/A cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs13108904 0.743 rs11729037 chr4:1387298 A/G cg13395646 chr4:1353034 KIAA1530 -0.41 -5.26 -0.43 6.02e-7 Obesity-related traits; TGCT cis rs12188164 0.965 rs72717438 chr5:448663 C/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs36051895 0.625 rs11792531 chr9:5152203 T/C cg02405213 chr9:5042618 JAK2 -0.7 -8.84 -0.62 8.02e-15 Pediatric autoimmune diseases; TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg22166914 chr1:53195759 ZYG11B 0.33 5.33 0.43 4.4e-7 Monocyte count; TGCT cis rs7940866 0.838 rs10750455 chr11:130800330 C/T cg05962950 chr11:130786565 SNX19 0.72 7.38 0.55 2.04e-11 Schizophrenia; TGCT cis rs57994353 0.861 rs34936112 chr9:139327062 G/A cg13741927 chr9:139327495 INPP5E -0.27 -6.13 -0.48 1.06e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs4953076 0.573 rs6734443 chr2:44408282 G/C cg00619915 chr2:44497795 NA -0.23 -5.1 -0.42 1.22e-6 Height; TGCT cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs1801251 1.000 rs6724117 chr2:233593660 T/G cg08000102 chr2:233561755 GIGYF2 0.63 6.53 0.51 1.51e-9 Coronary artery disease; TGCT cis rs7312933 0.737 rs10880261 chr12:42573822 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 4.99 0.41 1.99e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7089973 0.624 rs61867965 chr10:116574794 A/T cg03647239 chr10:116582469 FAM160B1 0.58 5.31 0.43 4.95e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs72781680 0.898 rs12614616 chr2:23996501 T/G cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs1153858 1.000 rs2461702 chr15:45647427 A/G cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs875971 0.862 rs13536 chr7:66019190 G/A cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs2933343 0.951 rs789251 chr3:128576770 G/A cg11901034 chr3:128598214 ACAD9 -0.63 -5.14 -0.42 1.05e-6 IgG glycosylation; TGCT cis rs11031096 0.542 rs1155146 chr11:3971020 G/A cg18678763 chr11:4115507 RRM1 -0.42 -5.14 -0.42 1.05e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg17554472 chr22:41940697 POLR3H -0.46 -4.79 -0.39 4.71e-6 Vitiligo; TGCT cis rs13323323 0.842 rs56377787 chr3:44293513 A/G cg04389838 chr3:44770851 ZNF501 -0.42 -4.57 -0.38 1.15e-5 IgG glycosylation; TGCT cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.72 0.52 5.82e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg01802117 chr1:53393560 SCP2 0.46 5.51 0.44 1.95e-7 Monocyte count; TGCT cis rs2688608 1.000 rs2688608 chr10:75658349 G/T cg02947784 chr10:75434997 AGAP5 0.16 4.45 0.37 1.86e-5 Inflammatory bowel disease; TGCT cis rs6671200 0.541 rs7555339 chr1:95691579 G/A cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.74e-11 Stearic acid (18:0) levels; TGCT cis rs10779751 0.610 rs2486921 chr1:11124943 G/A cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs7208859 0.614 rs73265646 chr17:29244023 C/T cg14008862 chr17:28927542 LRRC37B2 0.73 4.8 0.4 4.43e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs629535 0.551 rs62513429 chr8:70149995 A/C cg21567404 chr3:27674614 NA -0.51 -7.55 -0.56 8.15e-12 Dupuytren's disease; TGCT cis rs9916302 0.605 rs2879258 chr17:37399379 G/T cg03321784 chr17:37729644 NA 0.44 4.47 0.37 1.77e-5 Glomerular filtration rate (creatinine); TGCT cis rs9818758 0.505 rs11716159 chr3:49631585 G/A cg00383909 chr3:49044727 WDR6 1.31 6.63 0.51 9.3e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg00684032 chr4:1343700 KIAA1530 0.22 4.9 0.4 2.93e-6 Obesity-related traits; TGCT cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg21724239 chr8:58056113 NA 0.39 5.28 0.43 5.67e-7 Developmental language disorder (linguistic errors); TGCT cis rs2025751 0.512 rs6935608 chr6:51687277 A/C cg23457901 chr6:52402140 TRAM2 -0.22 -4.5 -0.37 1.57e-5 Intraocular pressure; TGCT cis rs1008375 0.966 rs4698636 chr4:17632834 T/C cg16339924 chr4:17578868 LAP3 0.64 5.33 0.43 4.52e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs9807989 0.507 rs6706002 chr2:103006104 A/G cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs9443645 0.869 rs9343827 chr6:79501036 A/G cg09184832 chr6:79620586 NA -0.45 -4.84 -0.4 3.76e-6 Intelligence (multi-trait analysis); TGCT cis rs13191362 1.000 rs34594856 chr6:163051845 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.92 7.24 0.55 4.11e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4927850 1.000 rs10881564 chr3:195750326 C/T cg22891161 chr3:195456627 MUC20 -0.23 -5.35 -0.43 4.08e-7 Pancreatic cancer; TGCT cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg02725872 chr8:58115012 NA -0.36 -4.51 -0.38 1.51e-5 Developmental language disorder (linguistic errors); TGCT cis rs4689388 0.856 rs4308430 chr4:6294095 A/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3820928 0.560 rs55635053 chr2:227952154 G/A cg11843606 chr2:227700838 RHBDD1 -0.49 -4.56 -0.38 1.21e-5 Pulmonary function; TGCT cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg03351412 chr1:154909251 PMVK 0.52 4.8 0.4 4.51e-6 Prostate cancer; TGCT cis rs9549367 0.577 rs3024713 chr13:113813321 G/A cg00898013 chr13:113819073 PROZ -0.55 -6.52 -0.51 1.62e-9 Platelet distribution width; TGCT cis rs7811142 0.830 rs11769057 chr7:99964661 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg03303774 chr4:1407052 NA -0.32 -4.92 -0.4 2.7e-6 Obesity-related traits; TGCT cis rs9549260 0.755 rs2721071 chr13:41144507 G/A cg21288729 chr13:41239152 FOXO1 0.99 10.25 0.68 3.18e-18 Red blood cell count; TGCT cis rs3785574 0.962 rs2584633 chr17:61879501 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.68 0.45 9.24e-8 Height; TGCT cis rs6558174 0.965 rs4872524 chr8:22489537 A/G cg03733263 chr8:22462867 KIAA1967 0.68 5.47 0.44 2.42e-7 Breast cancer; TGCT cis rs1008375 1.000 rs917665 chr4:17668504 A/C cg16339924 chr4:17578868 LAP3 -0.55 -4.74 -0.39 5.85e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9486719 1.000 rs6921291 chr6:97066242 C/T cg18709589 chr6:96969512 KIAA0776 -0.75 -5.36 -0.43 4e-7 Migraine;Coronary artery disease; TGCT cis rs13177918 0.629 rs2070842 chr5:149824223 T/C cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.6 -0.38 1.03e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs9388451 0.626 rs1343116 chr6:126069702 C/A cg05039488 chr6:79577232 IRAK1BP1 -0.87 -9.71 -0.66 6.39e-17 Brugada syndrome; TGCT cis rs72945132 0.882 rs6592552 chr11:70223831 A/T cg00319359 chr11:70116639 PPFIA1 0.96 7.04 0.53 1.13e-10 Coronary artery disease; TGCT cis rs838147 0.507 rs1704773 chr19:49209566 A/G cg13540341 chr19:49222985 MAMSTR -0.37 -4.98 -0.41 2.08e-6 Dietary macronutrient intake; TGCT cis rs17376456 0.877 rs13185660 chr5:93336500 G/A cg25358565 chr5:93447407 FAM172A 0.97 8.5 0.61 5.11e-14 Diabetic retinopathy; TGCT cis rs10789491 1.000 rs601060 chr1:47139580 C/G cg15501359 chr1:47185051 KIAA0494 -0.81 -8.17 -0.59 2.99e-13 Response to hepatitis C treatment; TGCT cis rs5769765 0.819 rs9616379 chr22:50312035 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs1775715 0.870 rs1755084 chr10:32253709 C/T cg14930904 chr10:32216787 ARHGAP12 0.48 4.51 0.38 1.49e-5 Bipolar disorder with mood-incongruent psychosis; TGCT trans rs1974653 0.672 rs1558497 chr22:20071899 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs36051895 0.559 rs6476949 chr9:5208048 G/A cg02405213 chr9:5042618 JAK2 -0.68 -8.65 -0.61 2.23e-14 Pediatric autoimmune diseases; TGCT trans rs629535 0.814 rs614050 chr8:70065642 G/A cg21567404 chr3:27674614 NA 0.57 9.11 0.63 1.82e-15 Dupuytren's disease; TGCT cis rs6733011 0.500 rs10182043 chr2:99417433 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -4.53 -0.38 1.36e-5 Bipolar disorder; TGCT cis rs7582180 0.629 rs12621892 chr2:100947124 G/C cg14675211 chr2:100938903 LONRF2 0.5 4.79 0.39 4.74e-6 Intelligence (multi-trait analysis); TGCT cis rs7715806 0.500 rs2307115 chr5:74990348 T/C cg19683494 chr5:74908142 NA 0.57 4.92 0.4 2.71e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg20607798 chr8:58055168 NA 0.45 4.66 0.39 7.88e-6 Developmental language disorder (linguistic errors); TGCT cis rs11098499 0.863 rs58452170 chr4:120459674 A/T cg09307838 chr4:120376055 NA 0.71 6.72 0.52 5.79e-10 Corneal astigmatism; TGCT cis rs12477438 0.501 rs11683188 chr2:99724512 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT trans rs1814175 0.615 rs11040654 chr11:49939485 T/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs2956278 0.717 rs2929749 chr12:84681345 G/A cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs796364 1.000 rs281788 chr2:200783705 A/T cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs11098499 0.954 rs6849561 chr4:120409694 C/G cg09307838 chr4:120376055 NA -0.71 -6.7 -0.52 6.42e-10 Corneal astigmatism; TGCT cis rs556990 0.574 rs473598 chr13:113801189 C/T cg00898013 chr13:113819073 PROZ -0.56 -7.28 -0.55 3.39e-11 Blood protein levels; TGCT cis rs9611565 0.921 rs2235846 chr22:41741042 G/C cg03806693 chr22:41940476 POLR3H -0.87 -9.3 -0.64 6.07e-16 Vitiligo; TGCT cis rs17253792 0.822 rs78824140 chr14:56042715 G/T cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs62380364 0.602 rs589544 chr5:88064462 T/C cg22951263 chr5:87985283 NA -0.59 -6.27 -0.49 5.5e-9 Intelligence (multi-trait analysis); TGCT cis rs7914558 1.000 rs2275271 chr10:104814162 T/C cg04362960 chr10:104952993 NT5C2 0.61 5.46 0.44 2.44e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9942416 0.660 rs1817869 chr5:74989037 T/C cg19683494 chr5:74908142 NA 0.59 6.26 0.49 5.62e-9 Age-related disease endophenotypes; TGCT cis rs79349575 0.749 rs12601672 chr17:47006493 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs986417 1.000 rs1072328 chr14:60876439 C/G cg27398547 chr14:60952738 C14orf39 -1.41 -9.11 -0.63 1.75e-15 Gut microbiota (bacterial taxa); TGCT cis rs7267979 0.932 rs431579 chr20:25470056 T/C cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9677476 0.516 rs2032953 chr2:232035793 C/T cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs317689 0.819 rs317683 chr12:69713630 T/G cg11871910 chr12:69753446 YEATS4 0.52 4.49 0.37 1.59e-5 Response to diuretic therapy; TGCT cis rs9346649 0.777 rs9346522 chr6:168490164 T/A cg02770688 chr6:168491649 NA -0.33 -6.18 -0.49 8.28e-9 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg08125733 chr17:73851984 WBP2 0.96 6.42 0.5 2.59e-9 Psoriasis; TGCT cis rs5750830 0.649 rs4384886 chr22:39793766 C/T cg24399712 chr22:39784796 NA -1.07 -13.42 -0.77 6.63e-26 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.623 rs7212991 chr17:29143749 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7811142 0.666 rs28401739 chr7:99905684 A/G cg00814883 chr7:100076585 TSC22D4 -0.82 -8.23 -0.59 2.14e-13 Platelet count; TGCT cis rs11107903 1.000 rs11107909 chr12:95521370 A/G cg10621809 chr12:95840313 NA -0.68 -5.04 -0.41 1.57e-6 Coronary artery disease; TGCT trans rs10435719 0.902 rs7014580 chr8:11803262 C/G cg15556689 chr8:8085844 FLJ10661 0.77 7.31 0.55 2.93e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs950776 0.545 rs28444683 chr15:78984507 C/A cg21242079 chr15:79101063 ADAMTS7 -0.3 -4.94 -0.41 2.44e-6 Sudden cardiac arrest; TGCT cis rs9611565 0.559 rs7290991 chr22:41964361 C/G cg06481639 chr22:41940642 POLR3H -0.67 -5.71 -0.46 7.87e-8 Vitiligo; TGCT cis rs6582630 0.519 rs4406888 chr12:38293312 A/C cg26384229 chr12:38710491 ALG10B 0.8 7.08 0.54 9.28e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs617219 0.737 rs1275103 chr5:78448105 C/G cg05890484 chr5:78407552 BHMT 0.37 5.03 0.41 1.7e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs13424612 1.000 rs34849118 chr2:240919912 T/C cg26363272 chr2:240904871 NDUFA10 0.28 4.67 0.39 7.7e-6 Odorant perception (isobutyraldehyde); TGCT cis rs7945705 0.902 rs2568059 chr11:8884161 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.48 -5.5 -0.44 2.03e-7 Hemoglobin concentration; TGCT cis rs7027203 0.828 rs10122041 chr9:96615517 A/G cg13679303 chr9:96623674 NA -0.66 -10.78 -0.7 1.64e-19 DNA methylation (variation); TGCT cis rs13191362 0.935 rs67084568 chr6:162988548 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.32 0.43 4.73e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4076764 0.958 rs11590567 chr1:163396438 A/G cg24596788 chr1:163392923 NA -0.17 -4.74 -0.39 5.85e-6 Motion sickness; TGCT cis rs2288073 0.965 rs10173949 chr2:24410256 A/C cg02683114 chr2:24398427 C2orf84 -0.24 -5.72 -0.46 7.53e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs3008870 1.000 rs3008856 chr1:67387901 T/C cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs9916302 0.861 rs8079590 chr17:37426201 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs2997447 0.846 rs61775427 chr1:26408768 G/A cg03844060 chr1:26490628 NA 0.27 4.46 0.37 1.82e-5 QRS complex (12-leadsum); TGCT cis rs1568889 0.641 rs34857148 chr11:28481976 T/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 5.25 0.43 6.39e-7 Bipolar disorder; TGCT cis rs2637266 1.000 rs7073355 chr10:78354419 G/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs7726839 0.540 rs72705097 chr5:655067 G/A cg20362242 chr5:692897 TPPP 0.51 4.49 0.37 1.61e-5 Obesity-related traits; TGCT cis rs2932538 0.885 rs3762335 chr1:113100548 C/T cg22162597 chr1:113214053 CAPZA1 0.27 5.89 0.47 3.46e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs5167 0.750 rs3786505 chr19:45490570 A/G cg09555818 chr19:45449301 APOC2 0.23 5.02 0.41 1.78e-6 Blood protein levels; TGCT cis rs10986311 0.816 rs912355 chr9:127090966 T/C cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.48 0.37 1.66e-5 Vitiligo; TGCT cis rs2721195 0.845 rs3757966 chr8:145744618 G/A cg17328964 chr8:145687451 CYHR1 -0.44 -6.25 -0.49 6.15e-9 Age at first birth; TGCT cis rs3008870 0.583 rs11208978 chr1:67442210 C/T cg11518657 chr1:67396239 MIER1 -0.6 -4.76 -0.39 5.32e-6 Lymphocyte percentage of white cells; TGCT cis rs908922 0.676 rs1572533 chr1:152509742 T/C cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT trans rs10506458 0.915 rs12423078 chr12:63397529 C/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg20999797 chr1:1681921 NA 0.18 4.69 0.39 7.02e-6 Body mass index; TGCT cis rs611744 0.967 rs637358 chr8:109197454 C/T cg21045802 chr8:109455806 TTC35 0.5 4.5 0.37 1.53e-5 Dupuytren's disease; TGCT cis rs4076764 0.958 rs11584957 chr1:163392937 C/T cg24596788 chr1:163392923 NA -0.16 -4.68 -0.39 7.43e-6 Motion sickness; TGCT cis rs12118280 0.921 rs72693452 chr1:108740482 G/A cg11967332 chr1:108735228 SLC25A24 0.39 5.44 0.44 2.74e-7 Myeloid white cell count; TGCT cis rs4665809 1.000 rs11126364 chr2:26314515 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.791 rs401561 chr6:145835917 G/T cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1797081 0.934 rs1797077 chr10:16853252 C/T cg23933602 chr10:16859644 RSU1 0.97 11.35 0.71 6.47e-21 Platelet distribution width; TGCT cis rs6087990 0.899 rs6087999 chr20:31363774 A/G cg13636640 chr20:31349939 DNMT3B 1.11 14.99 0.8 1.29e-29 Ulcerative colitis; TGCT cis rs6570726 0.818 rs412350 chr6:145852409 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.53 0.65 1.77e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4700695 0.614 rs371246 chr5:65209126 G/A cg21114390 chr5:65439923 SFRS12 0.67 4.69 0.39 7.07e-6 Facial morphology (factor 19); TGCT cis rs514406 0.825 rs3863643 chr1:53224577 C/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.42e-13 Monocyte count; TGCT cis rs7726839 0.540 rs72705097 chr5:655067 G/A cg09021430 chr5:549028 NA -0.45 -6.27 -0.49 5.56e-9 Obesity-related traits; TGCT cis rs514406 0.758 rs532242 chr1:53308665 C/G cg25767906 chr1:53392781 SCP2 -0.51 -5.78 -0.46 5.71e-8 Monocyte count; TGCT cis rs1865760 1.000 rs3799372 chr6:25922311 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.21 0.49 7.42e-9 Height; TGCT cis rs7923452 0.938 rs34560372 chr10:30773831 G/A cg18806716 chr10:30721971 MAP3K8 0.7 6.23 0.49 6.55e-9 Itch intensity from mosquito bite; TGCT cis rs28595532 0.920 rs115797971 chr4:119779620 A/G cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs9733 0.596 rs2867304 chr1:150630995 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs12643440 0.503 rs34795372 chr4:17142116 T/C cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs9486715 0.867 rs9372106 chr6:96875058 T/C cg06623918 chr6:96969491 KIAA0776 1.09 15.47 0.81 1.02e-30 Headache; TGCT cis rs875971 0.838 rs2173570 chr7:65762963 T/A cg18876405 chr7:65276391 NA -0.34 -5.09 -0.42 1.27e-6 Aortic root size; TGCT cis rs9535307 0.615 rs3736830 chr13:50306221 G/C cg03651054 chr13:50194643 NA 0.37 4.49 0.37 1.61e-5 Obesity-related traits; TGCT cis rs6815814 0.898 rs1106956 chr4:38889811 A/G cg02016764 chr4:38805732 TLR1 -0.35 -5.31 -0.43 4.95e-7 Breast cancer; TGCT cis rs13064411 0.542 rs9877649 chr3:113226874 C/T cg18753928 chr3:113234510 CCDC52 -0.56 -4.72 -0.39 6.3e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs1163251 0.902 rs639761 chr1:120217558 G/A cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs7829975 0.617 rs4841071 chr8:8791144 G/T cg06636001 chr8:8085503 FLJ10661 0.69 6.55 0.51 1.35e-9 Mood instability; TGCT cis rs16958440 0.867 rs12386092 chr18:44672058 C/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg15383120 chr6:291909 DUSP22 -0.67 -6.91 -0.53 2.3e-10 Menopause (age at onset); TGCT cis rs7715806 0.500 rs72633984 chr5:75005899 A/G cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs3015497 0.967 rs3015483 chr14:51137474 C/G cg04730355 chr14:51134070 SAV1 -0.53 -4.64 -0.38 8.78e-6 Mean platelet volume; TGCT cis rs7829975 0.577 rs17684466 chr8:8545233 G/A cg15556689 chr8:8085844 FLJ10661 -0.53 -4.5 -0.37 1.53e-5 Mood instability; TGCT cis rs72945132 0.882 rs11235755 chr11:70136323 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs10746514 1.000 rs10864715 chr1:232243817 G/A cg09506761 chr1:232265262 NA 0.54 5.49 0.44 2.13e-7 Response to statin therapy; TGCT cis rs11673344 0.504 rs2595555 chr19:37491121 C/T cg08039142 chr19:36980659 ZNF566 0.59 5.58 0.45 1.41e-7 Obesity-related traits; TGCT cis rs9677476 0.516 rs6746156 chr2:231967210 A/G cg27665808 chr2:232055229 NA 0.37 4.68 0.39 7.25e-6 Food antigen IgG levels; TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs10510102 0.748 rs11200297 chr10:123732431 A/G cg23691251 chr10:123688108 ATE1 -0.72 -5.21 -0.42 7.69e-7 Breast cancer; TGCT cis rs2242116 0.592 rs2290545 chr3:46967040 C/T cg27129171 chr3:47204927 SETD2 0.58 4.96 0.41 2.26e-6 Birth weight; TGCT cis rs6912958 0.559 rs242279 chr6:88048191 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.47 6.29 0.49 5.04e-9 Monocyte percentage of white cells; TGCT cis rs1056107 0.541 rs2150258 chr9:115174608 T/C cg02332936 chr9:115140584 NA -0.27 -4.59 -0.38 1.09e-5 Colorectal cancer; TGCT cis rs986417 0.901 rs11158292 chr14:61043183 G/T cg18240143 chr14:60952599 C14orf39 0.88 4.78 0.39 4.84e-6 Gut microbiota (bacterial taxa); TGCT cis rs12048904 0.505 rs6577209 chr1:101255080 A/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.68 5.42 0.44 2.99e-7 Multiple sclerosis; TGCT cis rs6088580 0.634 rs6059892 chr20:33105766 A/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg07424592 chr7:64974309 NA 1.35 7.66 0.57 4.49e-12 Diabetic kidney disease; TGCT cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg17554472 chr22:41940697 POLR3H -0.48 -5.1 -0.42 1.26e-6 Vitiligo; TGCT cis rs11098499 0.863 rs2306456 chr4:120472422 C/G cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs2657888 0.965 rs67036743 chr12:56948786 C/A cg23932658 chr12:57637574 STAC3 -0.53 -4.71 -0.39 6.4e-6 Adiponectin levels; TGCT cis rs7772486 0.686 rs1569540 chr6:146069112 A/G cg05347473 chr6:146136440 FBXO30 -0.49 -4.52 -0.38 1.42e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.546 rs1456207 chr4:98676911 G/A cg17366294 chr4:99064904 C4orf37 0.58 5.36 0.43 3.87e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3008870 0.816 rs1118392 chr1:67366549 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.83 -9.16 -0.64 1.32e-15 Lymphocyte percentage of white cells; TGCT cis rs7923452 0.507 rs215494 chr10:30776589 T/G cg18806716 chr10:30721971 MAP3K8 -0.61 -7.41 -0.55 1.69e-11 Itch intensity from mosquito bite; TGCT cis rs9653442 0.648 rs6733895 chr2:100666082 C/G cg22139774 chr2:100720529 AFF3 -0.42 -7.51 -0.56 9.98e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7927592 0.513 rs689075 chr11:68194432 A/C cg16797656 chr11:68205561 LRP5 0.29 5.19 0.42 8.33e-7 Total body bone mineral density; TGCT cis rs873946 0.590 rs12783478 chr10:134550700 A/G cg14827481 chr10:134361889 INPP5A 0.29 4.67 0.39 7.64e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4906332 1.000 rs55731474 chr14:103878481 G/A cg26031613 chr14:104095156 KLC1 -0.5 -4.45 -0.37 1.86e-5 Coronary artery disease; TGCT cis rs57221529 0.766 rs72704799 chr5:551457 C/G cg09021430 chr5:549028 NA -0.4 -5.14 -0.42 1.02e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7635838 0.565 rs347592 chr3:11248656 T/C cg00170343 chr3:11313890 ATG7 0.6 5.62 0.45 1.18e-7 HDL cholesterol; TGCT cis rs7582180 0.591 rs2241810 chr2:101011877 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 6.02e-6 Intelligence (multi-trait analysis); TGCT cis rs8068544 0.818 rs78333491 chr17:40163138 A/G cg13092355 chr17:39992602 KLHL10;NT5C3L -0.95 -4.55 -0.38 1.24e-5 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs13217239 0.646 rs10946897 chr6:26995251 A/C cg05738196 chr6:26577821 NA 0.49 4.75 0.39 5.45e-6 Schizophrenia; TGCT cis rs7113874 0.569 rs10769916 chr11:8598214 G/A cg14521421 chr11:8862019 ST5 0.28 4.44 0.37 1.96e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg11494091 chr17:61959527 GH2 -0.6 -15.93 -0.82 8.72e-32 Prudent dietary pattern; TGCT cis rs13242816 1.000 rs36004201 chr7:116126310 C/A cg02799643 chr7:116139180 CAV2 -0.45 -5.46 -0.44 2.49e-7 P wave duration; TGCT cis rs2228479 0.850 rs11644213 chr16:89837367 C/T cg06558623 chr16:89946397 TCF25 -0.45 -4.5 -0.37 1.55e-5 Skin colour saturation; TGCT cis rs1564271 0.528 rs2209350 chr10:26987779 A/G cg24343755 chr10:26987087 PDSS1 -0.52 -4.58 -0.38 1.12e-5 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; TGCT cis rs12765878 0.557 rs10883928 chr10:105615074 C/T cg11005552 chr10:105648138 OBFC1 -0.39 -6.06 -0.48 1.54e-8 Coronary artery disease; TGCT cis rs941873 0.835 rs4246944 chr10:81105684 C/T cg09469691 chr10:81107165 PPIF 0.56 5.54 0.45 1.71e-7 Height; TGCT cis rs3733585 0.648 rs7378305 chr4:9954893 C/T cg00071950 chr4:10020882 SLC2A9 -0.57 -6.75 -0.52 5.09e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2033711 0.870 rs3764534 chr19:58929136 G/A cg04608855 chr19:58913158 NA 0.58 5.76 0.46 6.36e-8 Uric acid clearance; TGCT cis rs9926296 0.715 rs467035 chr16:89740285 C/G cg04287289 chr16:89883240 FANCA 0.47 4.46 0.37 1.8e-5 Vitiligo; TGCT cis rs453301 0.657 rs36056437 chr8:8792865 T/G cg06636001 chr8:8085503 FLJ10661 -0.64 -5.33 -0.43 4.51e-7 Joint mobility (Beighton score); TGCT cis rs8177253 1.000 rs8177247 chr3:133479499 T/G cg11941060 chr3:133502564 NA -0.29 -6.15 -0.48 9.6e-9 Iron status biomarkers; TGCT cis rs10782582 0.593 rs115291524 chr1:76141811 A/G cg03433033 chr1:76189801 ACADM -0.64 -7.25 -0.55 3.84e-11 Daytime sleep phenotypes; TGCT cis rs9733 0.569 rs11204691 chr1:150644339 A/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs6964587 0.904 rs2023785 chr7:91547369 C/A cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs3806843 0.576 rs246003 chr5:140340865 C/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs40363 0.857 rs55989968 chr16:3530658 C/G cg22508957 chr16:3507546 NAT15 0.54 5.04 0.41 1.59e-6 Tuberculosis; TGCT cis rs1150668 0.796 rs213237 chr6:28323938 T/C cg19488431 chr6:28601329 NA 0.2 4.44 0.37 1.99e-5 Pubertal anthropometrics; TGCT trans rs7726839 0.540 rs72703083 chr5:595365 C/T cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs317689 0.690 rs595348 chr12:69638610 T/C cg11871910 chr12:69753446 YEATS4 0.53 4.47 0.37 1.77e-5 Response to diuretic therapy; TGCT cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg17054783 chr10:134559939 INPP5A 0.26 5.0 0.41 1.94e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1205863 1.000 rs1205884 chr6:11947933 A/G cg07106625 chr6:11870215 NA -0.51 -5.05 -0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs425277 0.606 rs12082939 chr1:2078922 C/T cg03732007 chr1:2071316 PRKCZ 0.28 6.76 0.52 4.87e-10 Height; TGCT cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs2836950 0.520 rs8133927 chr21:40689961 G/T cg06238570 chr21:40685208 BRWD1 -0.63 -6.31 -0.49 4.41e-9 Menarche (age at onset); TGCT cis rs7267979 0.966 rs8123949 chr20:25388133 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3812831 0.695 rs7983872 chr13:114944781 T/G cg15513719 chr13:114904418 NA 0.37 4.64 0.38 8.77e-6 Schizophrenia; TGCT cis rs3784262 1.000 rs10851631 chr15:58242193 C/T cg12031962 chr15:58353849 ALDH1A2 -0.47 -7.12 -0.54 7.85e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs35306767 0.761 rs34480046 chr10:1027440 A/G cg20503657 chr10:835505 NA 0.59 6.67 0.51 7.75e-10 Eosinophil percentage of granulocytes; TGCT cis rs7666738 0.712 rs34043080 chr4:99008748 G/C cg17366294 chr4:99064904 C4orf37 0.68 6.92 0.53 2.11e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 0.965 rs697968 chr7:65535033 G/A cg18876405 chr7:65276391 NA -0.35 -5.19 -0.42 8.26e-7 Aortic root size; TGCT cis rs35306767 0.761 rs12770173 chr10:1027108 A/C cg18964960 chr10:1102726 WDR37 0.74 5.31 0.43 4.97e-7 Eosinophil percentage of granulocytes; TGCT cis rs986417 1.000 rs1033733 chr14:60932438 G/T cg27398547 chr14:60952738 C14orf39 1.49 10.81 0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs9486719 0.895 rs34051754 chr6:97007754 A/T cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs2486288 0.656 rs1060896 chr15:45554267 C/A cg26924012 chr15:45694286 SPATA5L1 -0.76 -7.83 -0.58 1.85e-12 Glomerular filtration rate; TGCT cis rs7523050 0.643 rs7519293 chr1:109399543 A/G cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs2249625 0.523 rs2496501 chr6:72885364 A/G cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs597539 0.652 rs507520 chr11:68666054 C/T cg21963583 chr11:68658836 MRPL21 0.36 6.04 0.48 1.64e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11148252 0.538 rs3368 chr13:52707240 C/G cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.84e-8 Lewy body disease; TGCT cis rs1018836 0.923 rs13267989 chr8:91581648 C/T cg16814680 chr8:91681699 NA -0.86 -9.06 -0.63 2.36e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7104764 1.000 rs76552490 chr11:212015 G/A cg18336825 chr11:236787 PSMD13;SIRT3 -1.02 -10.54 -0.69 6.26e-19 Menarche (age at onset); TGCT cis rs344364 0.511 rs337284 chr16:1954799 A/C cg26617929 chr16:1858877 NA -0.25 -4.48 -0.37 1.69e-5 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7226408 0.857 rs72888992 chr18:34572381 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs12220238 1.000 rs11000900 chr10:75918440 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.88 7.24 0.55 4.04e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3796352 1.000 rs35720014 chr3:52982110 A/C cg15956490 chr3:53032818 SFMBT1 0.61 6.11 0.48 1.17e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1801251 1.000 rs6437074 chr2:233712296 C/T cg25237894 chr2:233734115 C2orf82 -0.33 -5.88 -0.47 3.63e-8 Coronary artery disease; TGCT cis rs11642862 0.901 rs76345698 chr16:30946165 G/A cg01031475 chr16:30004376 HIRIP3 0.23 4.54 0.38 1.34e-5 Tonsillectomy; TGCT cis rs17741873 0.943 rs11000802 chr10:75654167 C/G cg07699608 chr10:75541558 CHCHD1 0.76 5.73 0.46 7.07e-8 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs78487399 0.634 rs6751035 chr2:43752407 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.78 4.8 0.4 4.5e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs111326718 1 rs111326718 chr10:104771211 A/AAAAAT cg15744005 chr10:104629667 AS3MT -0.4 -4.97 -0.41 2.21e-6 Reticulocyte count; TGCT cis rs9308731 0.623 rs2241844 chr2:111879364 C/T cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.1e-9 Chronic lymphocytic leukemia; TGCT cis rs245880 0.740 rs245887 chr7:29190408 G/A cg17163760 chr7:29186267 CPVL -0.44 -5.54 -0.45 1.73e-7 Warfarin maintenance dose; TGCT cis rs10186029 0.676 rs12614406 chr2:213955803 A/G cg08319019 chr2:214017104 IKZF2 -0.62 -5.8 -0.46 5.14e-8 Systemic sclerosis; TGCT cis rs1670533 1.000 rs651017 chr4:1091062 A/G cg27284194 chr4:1044797 NA 0.63 5.18 0.42 8.8e-7 Recombination rate (females); TGCT cis rs2302464 0.661 rs6822515 chr4:15743194 C/A cg16359663 chr4:15503662 CC2D2A -0.37 -4.95 -0.41 2.41e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7208859 0.623 rs11652533 chr17:29060601 A/C cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7249142 0.562 rs10854009 chr19:19284705 A/C cg26504305 chr19:19281019 LOC729991-MEF2B;MEF2B -0.33 -4.51 -0.38 1.48e-5 IgG glycosylation; TGCT cis rs4888262 0.526 rs7193508 chr16:74628630 G/T cg01733217 chr16:74700730 RFWD3 0.74 7.42 0.55 1.6e-11 Testicular germ cell tumor; TGCT cis rs7103648 0.669 rs7114011 chr11:47811309 A/C cg20307385 chr11:47447363 PSMC3 0.78 7.51 0.56 1.02e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs1493935 0.667 rs3133581 chr8:119826164 G/T cg17171407 chr8:119960777 TNFRSF11B -0.24 -4.46 -0.37 1.82e-5 Eosinophil percentage of white cells; TGCT cis rs600231 0.708 rs1784860 chr11:65240712 C/A cg17120908 chr11:65337727 SSSCA1 -0.55 -5.14 -0.42 1.03e-6 Bone mineral density; TGCT trans rs1814175 0.935 rs7479914 chr11:49661351 T/C cg15704280 chr7:45808275 SEPT13 -0.61 -6.78 -0.52 4.28e-10 Height; TGCT cis rs1215050 0.791 rs2695472 chr4:98855127 T/C cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.830 rs13112131 chr4:98976784 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9926296 0.585 rs1800337 chr16:89845194 A/G cg04287289 chr16:89883240 FANCA 0.94 11.7 0.72 9.44e-22 Vitiligo; TGCT cis rs1218582 0.682 rs12144978 chr1:154850445 G/A cg09359103 chr1:154839909 KCNN3 -0.69 -12.94 -0.76 9.12e-25 Prostate cancer; TGCT cis rs908922 0.676 rs1123567 chr1:152516023 G/A cg20991723 chr1:152506922 NA 0.47 6.34 0.49 3.9e-9 Hair morphology; TGCT cis rs12701220 0.520 rs7803208 chr7:1162084 C/T cg04025307 chr7:1156635 C7orf50 0.23 4.57 0.38 1.16e-5 Bronchopulmonary dysplasia; TGCT cis rs73198271 0.737 rs535094 chr8:8633928 A/G cg06636001 chr8:8085503 FLJ10661 -0.6 -4.45 -0.37 1.92e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2456568 0.802 rs1395386 chr11:93639331 A/G cg16099599 chr11:93583650 C11orf90 0.39 4.86 0.4 3.53e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.85 -0.4 3.69e-6 Developmental language disorder (linguistic errors); TGCT cis rs1891275 0.515 rs2421694 chr10:93516104 A/G cg07889827 chr10:93443413 NA -0.32 -6.8 -0.52 3.95e-10 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.705 rs16851731 chr1:15860240 A/G cg05660106 chr1:15850417 CASP9 1.16 14.71 0.8 5.81e-29 Systolic blood pressure; TGCT cis rs9527 1.000 rs4919690 chr10:104616500 C/T cg15744005 chr10:104629667 AS3MT 0.52 6.38 0.5 3.19e-9 Arsenic metabolism; TGCT cis rs778371 0.671 rs13008436 chr2:233719948 C/T cg08000102 chr2:233561755 GIGYF2 -0.67 -7.37 -0.55 2.13e-11 Schizophrenia; TGCT cis rs9828933 0.577 rs704374 chr3:63865947 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.75 4.52 0.38 1.41e-5 Type 2 diabetes; TGCT cis rs6424115 0.830 rs6680132 chr1:24198804 T/C cg15997130 chr1:24165203 NA 0.85 9.26 0.64 7.92e-16 Immature fraction of reticulocytes; TGCT cis rs611744 0.967 rs677842 chr8:109212468 A/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs28927680 0.655 rs11820589 chr11:116633862 G/A cg20660624 chr11:117307972 DSCAML1 -0.36 -4.62 -0.38 9.31e-6 Lipid traits;Triglycerides; TGCT cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg17054783 chr10:134559939 INPP5A 0.25 5.02 0.41 1.75e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs7618501 0.635 rs34080578 chr3:50026029 A/C cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.85e-16 Intelligence (multi-trait analysis); TGCT cis rs4805272 0.539 rs1075733 chr19:29324460 C/T cg04546413 chr19:29218101 NA 0.72 4.97 0.41 2.16e-6 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs12620999 0.878 rs7593514 chr2:237980691 A/G cg23555395 chr2:238036564 NA 0.26 4.72 0.39 6.19e-6 Systemic lupus erythematosus; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs17534004 1.000 rs17534109 chr13:31470937 C/G cg13251181 chr13:31481184 C13orf33 -0.34 -4.48 -0.37 1.65e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs10504229 0.683 rs7835498 chr8:58129780 A/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9926296 0.656 rs2376883 chr16:89826926 A/G cg08627397 chr16:89984028 MC1R -0.29 -4.55 -0.38 1.26e-5 Vitiligo; TGCT cis rs6866344 0.697 rs17184302 chr5:178127676 C/T cg03877680 chr5:178157825 ZNF354A 0.72 5.61 0.45 1.27e-7 Neutrophil percentage of white cells; TGCT cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg06873352 chr17:61820015 STRADA 0.49 5.47 0.44 2.33e-7 Prudent dietary pattern; TGCT cis rs9467711 0.651 rs72834677 chr6:26106604 C/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.57 -4.54 -0.38 1.33e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7769051 0.522 rs60631157 chr6:133094817 G/A cg07930552 chr6:133119739 C6orf192 1.21 4.81 0.4 4.24e-6 Type 2 diabetes nephropathy; TGCT cis rs7666738 0.830 rs11097598 chr4:98946057 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg08859206 chr1:53392774 SCP2 -0.44 -6.52 -0.51 1.63e-9 Monocyte count; TGCT cis rs2762353 0.574 rs9467570 chr6:25699283 C/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.75 7.79 0.57 2.32e-12 Blood metabolite levels; TGCT cis rs17384381 0.953 rs12130145 chr1:85828970 G/C cg16011679 chr1:85725395 C1orf52 0.86 6.57 0.51 1.25e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7599312 0.534 rs10182996 chr2:213404834 T/C cg16329650 chr2:213403929 ERBB4 1.06 16.47 0.83 5.13e-33 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs17376456 0.825 rs13171131 chr5:93223028 C/T cg21475434 chr5:93447410 FAM172A 0.7 4.86 0.4 3.51e-6 Diabetic retinopathy; TGCT cis rs6547741 0.935 rs4666004 chr2:27855052 T/A cg27432699 chr2:27873401 GPN1 0.19 4.55 0.38 1.28e-5 Oral cavity cancer; TGCT trans rs7819412 0.511 rs2409799 chr8:11435927 G/C cg15556689 chr8:8085844 FLJ10661 -0.77 -7.17 -0.54 6.04e-11 Triglycerides; TGCT cis rs12893668 0.703 rs2274267 chr14:104029449 G/A cg26031613 chr14:104095156 KLC1 -0.53 -4.43 -0.37 2.01e-5 Reticulocyte count; TGCT cis rs2797160 0.967 rs926854 chr6:126021780 A/G cg05901451 chr6:126070800 HEY2 0.74 6.21 0.49 7.18e-9 Endometrial cancer; TGCT cis rs13064411 0.627 rs9872168 chr3:113233132 A/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.68 -0.45 9.16e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs17473412 0.609 rs6595457 chr5:122867333 T/C cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs9807841 0.670 rs2738042 chr19:10790143 C/G cg17848348 chr19:10766748 ILF3 -0.4 -4.58 -0.38 1.12e-5 Inflammatory skin disease; TGCT cis rs13242816 1.000 rs35800921 chr7:116124041 G/A cg16553024 chr7:116138462 CAV2 -0.44 -4.59 -0.38 1.05e-5 P wave duration; TGCT cis rs12484776 0.786 rs17323591 chr22:40534211 T/A cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs61990749 0.597 rs10142722 chr14:78275549 A/T cg23188588 chr14:78226832 SNW1;C14orf178 0.7 4.86 0.4 3.53e-6 Fibroblast growth factor basic levels; TGCT cis rs1505368 0.837 rs10167244 chr2:213281310 A/G cg20637307 chr2:213403960 ERBB4 0.5 4.97 0.41 2.15e-6 Symmetrical dimethylarginine levels; TGCT cis rs7809950 1.000 rs2712215 chr7:107188207 A/G cg23024343 chr7:107201750 COG5 -0.35 -5.4 -0.44 3.21e-7 Coronary artery disease; TGCT cis rs422249 0.512 rs174583 chr11:61609750 A/G cg01500311 chr11:61656094 FADS3 0.29 4.91 0.4 2.78e-6 Trans fatty acid levels; TGCT cis rs875971 0.964 rs778721 chr7:65845397 C/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs9952991 0.941 rs2847278 chr18:12778715 C/T cg24737193 chr18:12778029 NA 0.54 6.03 0.48 1.76e-8 Inflammatory skin disease; TGCT cis rs597539 0.690 rs497149 chr11:68626639 A/T cg04772025 chr11:68637568 NA 0.61 6.7 0.52 6.38e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9894429 1.000 rs9674872 chr17:79581931 T/A cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs910316 1.000 rs175449 chr14:75590846 A/T cg08847533 chr14:75593920 NEK9 -0.94 -10.33 -0.68 2.03e-18 Height; TGCT cis rs9914544 0.564 rs9906799 chr17:18795317 A/G cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs56104184 0.725 rs1466896 chr19:49385253 C/G cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7193541 1.000 rs7193541 chr16:74664743 C/T cg01733217 chr16:74700730 RFWD3 -0.71 -7.18 -0.54 5.58e-11 Multiple myeloma; TGCT cis rs12765878 1.000 rs3814220 chr10:105647300 A/G cg11005552 chr10:105648138 OBFC1 0.44 7.69 0.57 4.01e-12 Coronary artery disease; TGCT cis rs4803468 1.000 rs284649 chr19:41926838 C/T cg09537434 chr19:41945824 ATP5SL -0.92 -10.57 -0.69 5.19e-19 Height; TGCT cis rs8177253 0.511 rs9830001 chr3:133433470 A/G cg08048268 chr3:133502702 NA 0.47 6.04 0.48 1.7e-8 Iron status biomarkers; TGCT cis rs6893807 0.778 rs7703782 chr5:87938557 A/T cg24804195 chr5:87968844 LOC645323 0.8 4.7 0.39 6.85e-6 Body mass index; TGCT cis rs6570726 0.738 rs4495284 chr6:145916617 T/A cg23711669 chr6:146136114 FBXO30 0.88 9.32 0.64 5.56e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7178424 0.840 rs4774427 chr15:62217444 T/C cg00456672 chr15:62358751 C2CD4A 0.32 4.73 0.39 5.96e-6 Height; TGCT cis rs7824557 0.602 rs11784544 chr8:11204503 G/C cg21775007 chr8:11205619 TDH 0.72 7.02 0.53 1.27e-10 Retinal vascular caliber; TGCT cis rs11627546 0.528 rs61980574 chr14:70363324 T/C cg10496350 chr14:71275911 MAP3K9 -0.98 -4.89 -0.4 3.03e-6 Red blood cell traits; TGCT cis rs7267979 1.000 rs422844 chr20:25445591 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2404602 0.735 rs62028423 chr15:76754514 G/A cg22467129 chr15:76604101 ETFA 0.49 5.1 0.42 1.24e-6 Blood metabolite levels; TGCT cis rs2458413 0.933 rs2669450 chr8:105371752 C/T cg04554929 chr8:105342491 NA 0.56 8.06 0.59 5.53e-13 Paget's disease; TGCT cis rs875971 0.830 rs587360 chr7:65522698 C/A cg18876405 chr7:65276391 NA 0.33 4.95 0.41 2.39e-6 Aortic root size; TGCT cis rs611744 0.967 rs584716 chr8:109178634 A/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs2887571 0.738 rs11613149 chr12:1637676 G/A cg01940102 chr12:1095972 NA 0.26 4.78 0.39 4.92e-6 Bone mineral density; TGCT cis rs10746514 0.804 rs1854822 chr1:232262270 G/C cg09506761 chr1:232265262 NA -0.49 -4.99 -0.41 2.01e-6 Response to statin therapy; TGCT cis rs7681440 0.647 rs11941110 chr4:90819569 T/C cg10208370 chr4:90758469 SNCA -0.57 -5.4 -0.44 3.23e-7 Dementia with Lewy bodies; TGCT cis rs36051895 0.695 rs7043489 chr9:5023604 A/C cg02405213 chr9:5042618 JAK2 -0.81 -11.27 -0.71 1.03e-20 Pediatric autoimmune diseases; TGCT trans rs916888 0.821 rs199506 chr17:44859031 A/G cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.85 8.66 0.61 2.16e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.632 rs966871 chr9:5121070 A/T cg02405213 chr9:5042618 JAK2 -0.76 -10.67 -0.69 2.98e-19 Pediatric autoimmune diseases; TGCT cis rs11828289 0.660 rs17306426 chr11:23222079 G/T cg20040320 chr11:23191996 NA 0.54 4.51 0.38 1.46e-5 Cancer; TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs908922 0.676 rs1001834 chr1:152495940 C/A cg20991723 chr1:152506922 NA 0.46 6.26 0.49 5.7e-9 Hair morphology; TGCT cis rs17169807 1.000 rs17170178 chr7:33349225 T/A cg06206957 chr7:33080615 NT5C3 0.32 4.44 0.37 1.97e-5 Smooth-surface caries; TGCT cis rs11718455 1.000 rs4682928 chr3:44037192 T/C cg08738300 chr3:44038990 NA 0.86 6.57 0.51 1.23e-9 Coronary artery disease; TGCT cis rs2153535 0.580 rs986060 chr6:8465428 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9467711 1.000 rs6923139 chr6:26313348 C/T cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs71597109 0.639 rs66638185 chr4:102729417 T/C cg14855874 chr4:102712397 BANK1 0.42 4.72 0.39 6.29e-6 Chronic lymphocytic leukemia; TGCT cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg13866156 chr1:1669148 SLC35E2 -0.23 -5.53 -0.44 1.8e-7 Body mass index; TGCT cis rs12148488 0.763 rs12900072 chr15:75307148 G/A cg10253484 chr15:75165896 SCAMP2 -0.6 -5.23 -0.43 6.95e-7 Caffeine consumption; TGCT cis rs2439831 1.000 rs2467743 chr15:43750346 T/A cg27015174 chr15:43622946 ADAL;LCMT2 0.81 5.66 0.45 9.81e-8 Lung cancer in ever smokers; TGCT cis rs79149102 0.579 rs73436579 chr15:75294514 C/T cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs17376456 0.877 rs10055741 chr5:93297187 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.87 0.4 3.26e-6 Diabetic retinopathy; TGCT cis rs1799949 0.965 rs8176161 chr17:41241390 C/A cg05368731 chr17:41323189 NBR1 1.2 14.59 0.79 1.08e-28 Menopause (age at onset); TGCT cis rs7552404 1.000 rs4949875 chr1:76173080 G/A cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9796 0.866 rs2928148 chr15:41401550 G/A cg18705301 chr15:41695430 NDUFAF1 0.47 6.09 0.48 1.34e-8 Menopause (age at onset); TGCT cis rs17102423 0.826 rs12887607 chr14:65596887 G/A cg11161011 chr14:65562177 MAX -0.57 -7.71 -0.57 3.46e-12 Obesity-related traits; TGCT cis rs921968 0.643 rs532475 chr2:219434208 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs72627509 0.680 rs66790703 chr4:57773908 G/A cg26694713 chr4:57773883 REST 0.72 6.46 0.5 2.14e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs875971 0.862 rs13232191 chr7:65986648 A/G cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs6701037 0.748 rs11583687 chr1:175132049 A/C cg08873628 chr1:175162347 KIAA0040 0.45 4.47 0.37 1.75e-5 Alcohol dependence; TGCT cis rs12762955 0.677 rs11250267 chr10:1156487 A/G cg20503657 chr10:835505 NA 0.46 5.04 0.41 1.63e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs514406 0.861 rs35581164 chr1:53271373 C/G cg25767906 chr1:53392781 SCP2 -0.47 -5.39 -0.44 3.38e-7 Monocyte count; TGCT cis rs921968 0.541 rs667251 chr2:219384384 C/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs67311347 1.000 rs7634375 chr3:40431946 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs12931792 0.712 rs2887799 chr16:30163833 G/A cg17640201 chr16:30407289 ZNF48 0.58 5.1 0.42 1.24e-6 Tonsillectomy; TGCT cis rs3806843 0.576 rs246037 chr5:140331846 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs4927850 0.752 rs7618864 chr3:195749561 G/A cg12923728 chr3:195709715 SDHAP1 -0.37 -7.65 -0.57 4.91e-12 Pancreatic cancer; TGCT cis rs4919694 1.000 rs12254254 chr10:104765605 C/T cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs10032931 0.962 rs7686970 chr4:96457107 G/A cg03008707 chr4:96468962 UNC5C -0.4 -5.26 -0.43 6.24e-7 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs10206020 0.921 rs72778009 chr2:1573322 G/T cg01028140 chr2:1542097 TPO -0.32 -4.99 -0.41 1.97e-6 IgG glycosylation; TGCT cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg03517284 chr6:25882590 NA -0.53 -5.43 -0.44 2.88e-7 Blood metabolite levels; TGCT cis rs12510870 0.599 rs16849659 chr4:74450500 A/G cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs35883536 0.647 rs2783703 chr1:101040794 T/C cg06223162 chr1:101003688 GPR88 0.42 8.0 0.58 7.5e-13 Monocyte count; TGCT cis rs1580019 0.961 rs1580021 chr7:32497702 T/G cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.61 0.56 5.93e-12 Cognitive ability; TGCT cis rs1005277 0.579 rs176880 chr10:38401417 C/G cg13531842 chr10:38383804 ZNF37A 0.39 4.58 0.38 1.13e-5 Extrinsic epigenetic age acceleration; TGCT cis rs2932538 0.961 rs2932534 chr1:113200797 A/G cg22162597 chr1:113214053 CAPZA1 0.26 5.87 0.47 3.81e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs700590 0.723 rs244753 chr5:88144520 A/G cg22951263 chr5:87985283 NA 0.54 5.06 0.41 1.48e-6 Educational attainment (years of education); TGCT cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg06238570 chr21:40685208 BRWD1 -0.8 -8.22 -0.59 2.31e-13 Cognitive function; TGCT cis rs7819412 0.783 rs28722721 chr8:10948968 G/A cg21775007 chr8:11205619 TDH -0.52 -4.86 -0.4 3.52e-6 Triglycerides; TGCT cis rs3779635 0.840 rs2322718 chr8:27257787 A/C cg17482963 chr8:27591911 CCDC25 -0.22 -4.57 -0.38 1.15e-5 Neuroticism; TGCT cis rs13177918 0.677 rs2070841 chr5:149824471 A/G cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12477438 0.520 rs11678456 chr2:99708237 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs25422 0.938 rs62422193 chr6:118912285 G/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.14 -0.42 1.02e-6 Renal cell carcinoma; TGCT cis rs12210905 0.688 rs115030474 chr6:27512220 C/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs11122272 0.735 rs2790897 chr1:231491712 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -6.83 -0.52 3.46e-10 Hemoglobin concentration; TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs6032067 0.636 rs6104093 chr20:43908297 T/C cg16667508 chr20:43936853 MATN4;RBPJL -0.47 -7.24 -0.54 4.21e-11 Blood protein levels; TGCT cis rs11971779 1.000 rs75919582 chr7:139054919 G/A cg07862535 chr7:139043722 LUC7L2 0.81 5.85 0.47 4.03e-8 Diisocyanate-induced asthma; TGCT cis rs1775715 0.966 rs1639132 chr10:32301260 G/A cg14930904 chr10:32216787 ARHGAP12 -0.52 -4.88 -0.4 3.24e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6463523 0.864 rs73047957 chr7:759373 A/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.94 11.59 0.72 1.71e-21 Subjective well-being; TGCT cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs7017914 0.934 rs7814274 chr8:71570411 C/T cg23757474 chr8:71581111 LACTB2;XKR9 0.52 4.85 0.4 3.6e-6 Bone mineral density; TGCT cis rs8056742 0.730 rs34949898 chr16:85069049 G/C cg00229868 chr16:85520891 NA 0.42 5.17 0.42 9.14e-7 Amyotrophic lateral sclerosis; TGCT cis rs9325144 0.647 rs12831609 chr12:39051576 C/A cg10518543 chr12:38710700 ALG10B -0.48 -4.47 -0.37 1.77e-5 Morning vs. evening chronotype; TGCT cis rs28595532 0.920 rs115982145 chr4:119605707 A/G cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.66e-7 Cannabis dependence symptom count; TGCT cis rs1042445 1.000 rs7625980 chr3:186393547 T/C cg13908232 chr3:186371902 NA 0.46 5.2 0.42 7.95e-7 Blood protein levels; TGCT cis rs78487399 0.808 rs116451849 chr2:43662911 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.45 -5.35 -0.43 4.03e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs514406 0.505 rs12726160 chr1:53175099 A/G cg16325326 chr1:53192061 ZYG11B 0.85 11.87 0.73 3.53e-22 Monocyte count; TGCT cis rs28595532 0.841 rs114735834 chr4:119772722 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs4642101 0.765 rs4321514 chr3:12825901 C/T cg05775895 chr3:12838266 CAND2 0.79 9.04 0.63 2.61e-15 QRS complex (12-leadsum); TGCT cis rs2692947 0.644 rs1168968 chr2:96825363 C/T cg23100626 chr2:96804247 ASTL 0.47 5.55 0.45 1.67e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9302001 0.883 rs7988127 chr13:95456386 C/T cg07483244 chr13:95358924 NA 0.35 4.47 0.37 1.72e-5 Panic disorder; TGCT cis rs35306767 0.903 rs61830933 chr10:934195 G/A cg26597838 chr10:835615 NA 0.81 12.42 0.74 1.61e-23 Eosinophil percentage of granulocytes; TGCT cis rs62103177 0.810 rs62103178 chr18:77624555 C/G cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs6840360 0.617 rs2724564 chr4:152349962 G/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs7226408 0.749 rs72892525 chr18:34670741 G/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs3540 0.557 rs11634314 chr15:91042066 A/C cg22089800 chr15:90895588 ZNF774 -0.75 -7.58 -0.56 6.96e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7208859 0.673 rs9895684 chr17:29242600 G/A cg18442181 chr17:29233375 C17orf42 -0.79 -4.68 -0.39 7.44e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4149178 0.722 rs9472031 chr6:43293101 C/T cg12269535 chr6:43142014 SRF -0.58 -4.84 -0.4 3.72e-6 Urate levels; TGCT cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs425277 0.606 rs2460001 chr1:2111030 T/C cg24578937 chr1:2090814 PRKCZ 0.27 7.01 0.53 1.38e-10 Height; TGCT cis rs7923609 1.000 rs4310508 chr10:65138573 A/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.15e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs7769051 0.522 rs7759524 chr6:133109574 A/G cg22852734 chr6:133119734 C6orf192 1.22 4.65 0.39 8.32e-6 Type 2 diabetes nephropathy; TGCT cis rs6912958 0.559 rs499373 chr6:88042062 A/T cg12350822 chr6:88032061 C6orf162;GJB7 0.45 5.88 0.47 3.49e-8 Monocyte percentage of white cells; TGCT cis rs7267979 0.903 rs2500400 chr20:25354705 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1541995 0.789 rs17584220 chr15:96227411 G/A cg00882281 chr15:96346592 NA 0.3 4.76 0.39 5.28e-6 Photic sneeze reflex; TGCT cis rs6032067 0.526 rs2743347 chr20:43920493 T/C cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -7.0 -0.53 1.41e-10 Blood protein levels; TGCT cis rs3845702 0.736 rs3843323 chr2:180856459 T/C cg01881094 chr2:180872142 CWC22 -1.07 -6.79 -0.52 4.2e-10 Schizophrenia; TGCT cis rs7611238 0.560 rs13317705 chr3:195086609 G/A cg27323046 chr3:195102265 ACAP2 0.39 5.17 0.42 9.08e-7 Body mass index; TGCT cis rs11577318 0.579 rs58034207 chr1:26683575 C/T cg14210634 chr1:25870291 LDLRAP1 0.53 4.62 0.38 9.33e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4595586 1.000 rs4768388 chr12:39223924 G/A cg10518543 chr12:38710700 ALG10B -0.49 -4.77 -0.39 5.05e-6 Morning vs. evening chronotype; TGCT cis rs735396 0.770 rs1169315 chr12:121443753 T/G cg02403541 chr12:121454288 C12orf43 0.76 7.42 0.55 1.58e-11 N-glycan levels; TGCT cis rs7539409 0.915 rs761404 chr1:84226766 G/T cg10977910 chr1:84465055 TTLL7 -0.83 -4.61 -0.38 9.68e-6 Alzheimer's disease; TGCT cis rs919433 0.679 rs13394214 chr2:198527371 C/T cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs6722750 0.905 rs10170666 chr2:64379672 G/A cg22352474 chr2:64371530 PELI1 0.77 7.07 0.54 1.01e-10 Neuroticism; TGCT cis rs1395 0.778 rs2078616 chr2:27441904 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.68 9.32 0.64 5.51e-16 Blood metabolite levels; TGCT cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg06634786 chr22:41940651 POLR3H -0.82 -7.7 -0.57 3.71e-12 Vitiligo; TGCT cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs2299587 0.650 rs12548412 chr8:17796970 G/T cg01800426 chr8:17659068 MTUS1 -0.65 -5.66 -0.45 9.98e-8 Economic and political preferences; TGCT cis rs8062405 0.721 rs151181 chr16:28490517 A/G cg09754948 chr16:28834200 ATXN2L 0.61 4.8 0.4 4.54e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs933688 1.000 rs6869717 chr5:90694797 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.15 0.59 3.39e-13 Smoking behavior; TGCT cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs4727027 0.835 rs6959224 chr7:148784495 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.73 0.39 6.03e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6912958 0.703 rs9353483 chr6:88097180 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.63 6.17 0.48 8.96e-9 Monocyte percentage of white cells; TGCT trans rs2832077 0.527 rs2142375 chr21:30223742 G/A cg14791747 chr16:20752902 THUMPD1 1.09 12.67 0.75 4.09e-24 Cognitive test performance; TGCT cis rs11098499 0.826 rs4472123 chr4:120236630 T/A cg09307838 chr4:120376055 NA 0.58 5.49 0.44 2.15e-7 Corneal astigmatism; TGCT cis rs8014204 0.901 rs6574200 chr14:75364451 C/T cg06637938 chr14:75390232 RPS6KL1 -0.73 -6.94 -0.53 1.95e-10 Caffeine consumption; TGCT cis rs6754311 0.731 rs745500 chr2:136583192 G/A cg07169764 chr2:136633963 MCM6 -0.61 -5.61 -0.45 1.25e-7 Mosquito bite size; TGCT cis rs6952808 0.531 rs3778991 chr7:2172455 G/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.28 -0.49 5.31e-9 Bipolar disorder and schizophrenia; TGCT trans rs7819412 0.875 rs11250121 chr8:11060311 A/C cg15556689 chr8:8085844 FLJ10661 -0.75 -7.37 -0.55 2.08e-11 Triglycerides; TGCT cis rs68170813 0.641 rs4730228 chr7:106904077 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs9534288 0.797 rs2182483 chr13:46582600 C/T cg15192986 chr13:46630673 CPB2 -0.51 -7.18 -0.54 5.61e-11 Blood protein levels; TGCT trans rs7618501 0.633 rs6771546 chr3:49968572 T/C cg21659725 chr3:3221576 CRBN 0.76 9.03 0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs77861329 1.000 rs893056 chr3:52109564 G/A cg08692210 chr3:52188851 WDR51A 0.86 4.44 0.37 1.98e-5 Macrophage inflammatory protein 1b levels; TGCT cis rs77216612 0.835 rs10845621 chr12:12887977 C/T cg09462578 chr12:12878428 APOLD1 -1.0 -8.3 -0.6 1.5e-13 Lymphocyte counts; TGCT cis rs73198271 0.563 rs74556999 chr8:8548459 C/T cg06636001 chr8:8085503 FLJ10661 -0.72 -4.69 -0.39 7.09e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9534288 0.664 rs1926446 chr13:46629995 A/C cg15192986 chr13:46630673 CPB2 0.49 6.89 0.53 2.45e-10 Blood protein levels; TGCT cis rs7666738 0.830 rs6532723 chr4:99052147 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10782582 0.593 rs4646960 chr1:76211103 C/A cg22875332 chr1:76189707 ACADM -0.49 -5.39 -0.44 3.35e-7 Daytime sleep phenotypes; TGCT cis rs4727027 0.866 rs1405124 chr7:148779618 C/T cg23583168 chr7:148888333 NA -0.69 -8.75 -0.62 1.29e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs16854884 0.739 rs1898265 chr3:143776096 A/G cg06585982 chr3:143692056 C3orf58 -0.63 -5.1 -0.42 1.23e-6 Economic and political preferences (feminism/equality); TGCT cis rs797680 0.930 rs12124771 chr1:93799239 A/G cg17826107 chr1:92977322 EVI5 -0.23 -5.19 -0.42 8.35e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs67311347 0.594 rs12629111 chr3:40285351 T/C cg13683864 chr3:40499215 RPL14 -0.74 -6.81 -0.52 3.71e-10 Renal cell carcinoma; TGCT cis rs6952808 0.595 rs3778983 chr7:2166319 T/G cg22963979 chr7:1858916 MAD1L1 -0.43 -6.94 -0.53 1.96e-10 Bipolar disorder and schizophrenia; TGCT cis rs7267979 0.903 rs2474769 chr20:25248725 C/T cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1865760 1.000 rs7739966 chr6:25906040 T/C cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs4664308 0.875 rs7593593 chr2:160933811 C/T cg03641300 chr2:160917029 PLA2R1 -0.28 -6.83 -0.52 3.43e-10 Idiopathic membranous nephropathy; TGCT cis rs477895 0.838 rs35090903 chr11:64000598 C/T cg04317338 chr11:64019027 PLCB3 0.81 6.93 0.53 2.07e-10 Mean platelet volume; TGCT cis rs2273156 1.000 rs2273156 chr14:35438799 T/C cg24764865 chr14:36295508 BRMS1L -0.6 -4.58 -0.38 1.12e-5 Immunoglobulin light chain (AL) amyloidosis; TGCT cis rs9581857 0.512 rs9581874 chr13:28086956 A/G cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7786808 0.552 rs896762 chr7:158182029 A/G cg01191920 chr7:158217561 PTPRN2 0.33 4.86 0.4 3.5e-6 Obesity-related traits; TGCT cis rs791888 0.929 rs791887 chr10:89411554 A/G cg13926569 chr10:89418898 PAPSS2 -0.35 -4.61 -0.38 9.95e-6 Magnesium levels; TGCT cis rs17270561 1.000 rs17270561 chr6:25820439 A/C cg15022984 chr6:26056706 HIST1H1C 0.71 4.63 0.38 9.03e-6 Iron status biomarkers; TGCT cis rs1008375 1.000 rs10939742 chr4:17659936 G/T cg10189774 chr4:17578691 LAP3 0.57 5.16 0.42 9.6e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2742417 1.000 rs2742392 chr3:45757282 T/C cg04837898 chr3:45731254 SACM1L -0.5 -5.13 -0.42 1.07e-6 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7582180 0.764 rs13006224 chr2:100917109 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.85 -0.4 3.55e-6 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.855 rs55697724 chr10:885622 T/C cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs853679 0.546 rs200990 chr6:27815823 T/G cg08798685 chr6:27730294 NA -0.34 -4.77 -0.39 5.13e-6 Depression; TGCT cis rs7666738 0.716 rs35195511 chr4:98859660 G/A cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs589448 0.867 rs623853 chr12:69753830 G/A cg20891283 chr12:69753455 YEATS4 0.91 10.33 0.68 1.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs7666738 0.680 rs11097613 chr4:99079991 G/T cg05340658 chr4:99064831 C4orf37 0.49 5.37 0.43 3.81e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs826838 1.000 rs826886 chr12:39095797 A/G cg26384229 chr12:38710491 ALG10B 0.84 7.87 0.58 1.5e-12 Heart rate; TGCT cis rs10504229 0.683 rs59528137 chr8:58138565 C/T cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs295140 0.632 rs4673905 chr2:201163783 A/G cg04283868 chr2:201171347 SPATS2L 0.55 4.97 0.41 2.21e-6 QT interval; TGCT cis rs734999 0.549 rs3828154 chr1:2524943 G/A cg18854424 chr1:2615690 NA 0.5 5.78 0.46 5.64e-8 Ulcerative colitis; TGCT cis rs5750830 0.645 rs756640 chr22:39779300 G/A cg02038168 chr22:39784481 NA -0.72 -6.24 -0.49 6.33e-9 Intelligence (multi-trait analysis); TGCT cis rs9381040 0.655 rs2268193 chr6:41024625 A/G cg03526776 chr6:41159608 TREML2 0.27 5.29 0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs2832191 1.000 rs2832189 chr21:30487414 C/T cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT cis rs6570726 0.905 rs375692 chr6:145840368 A/G cg23711669 chr6:146136114 FBXO30 0.69 6.22 0.49 6.89e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6088590 0.561 rs6087605 chr20:33180624 G/T cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs2153535 0.580 rs9379215 chr6:8481225 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs17253792 0.822 rs28513551 chr14:56094993 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs1048238 0.525 rs848214 chr1:16265422 A/G cg21385522 chr1:16154831 NA -0.61 -6.8 -0.52 3.89e-10 Systolic blood pressure; TGCT cis rs9443645 0.901 rs3805747 chr6:79672522 A/G cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.04 0.41 1.58e-6 Menopause (age at onset); TGCT cis rs6671200 0.748 rs34254763 chr1:95540961 T/C cg03123541 chr1:95699097 RWDD3 0.65 4.49 0.37 1.6e-5 Stearic acid (18:0) levels; TGCT cis rs74233809 1.000 rs78821730 chr10:104684544 G/A cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs7208859 0.673 rs12103759 chr17:29235687 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs2688608 1.000 rs2688610 chr10:75654931 A/G cg13918328 chr10:52500089 ASAH2B -0.67 -6.88 -0.53 2.56e-10 Inflammatory bowel disease; TGCT cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg00684032 chr4:1343700 KIAA1530 0.23 4.91 0.4 2.76e-6 Obesity-related traits; TGCT cis rs367943 0.966 rs348932 chr5:112812457 G/A cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs11098499 0.863 rs11947234 chr4:120474859 A/G cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs2070488 0.930 rs928813 chr3:38528537 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 8.99 0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs11690935 0.959 rs6433314 chr2:172660971 A/G cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs2235642 1.000 rs2076438 chr16:1584618 T/C cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.82 -0.4 4.09e-6 Coronary artery disease; TGCT cis rs17152411 0.817 rs4478950 chr10:126596425 T/C cg07906193 chr10:126599966 NA 0.43 5.31 0.43 4.92e-7 Height; TGCT cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.63 5.11 0.42 1.19e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs208520 1.000 rs12190316 chr6:66973365 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.82 7.48 0.56 1.21e-11 Exhaled nitric oxide output; TGCT cis rs2933343 0.951 rs796862 chr3:128593040 G/A cg11901034 chr3:128598214 ACAD9 -0.65 -5.12 -0.42 1.15e-6 IgG glycosylation; TGCT cis rs250677 0.522 rs7702695 chr5:148402550 T/A cg18129178 chr5:148520854 ABLIM3 -0.35 -4.58 -0.38 1.12e-5 Breast cancer; TGCT cis rs11748023 0.605 rs249616 chr5:139529656 C/T cg01081189 chr5:139537190 NA 0.26 4.48 0.37 1.69e-5 Intelligence (multi-trait analysis); TGCT cis rs8017423 0.935 rs17260827 chr14:90732703 G/A cg04374321 chr14:90722782 PSMC1 -0.79 -7.91 -0.58 1.24e-12 Mortality in heart failure; TGCT cis rs74181299 0.571 rs7559813 chr2:65278023 A/G cg05010058 chr2:65284262 CEP68 -0.48 -4.95 -0.41 2.36e-6 Pulse pressure; TGCT cis rs7226408 0.948 rs11660414 chr18:34376565 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.56 0.38 1.2e-5 Obesity-related traits; TGCT cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9640161 0.789 rs4554381 chr7:150025567 G/A cg17279839 chr7:150038598 RARRES2 0.43 4.6 0.38 1.02e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2204008 0.837 rs11612397 chr12:38357455 T/C cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs7267979 1.000 rs2424704 chr20:25273929 A/G cg16686733 chr20:25566563 NINL 0.58 5.75 0.46 6.46e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs62318906 chr4:99037110 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.95 7.54 0.56 8.47e-12 Platelet count; TGCT cis rs17826219 0.500 rs117560728 chr17:29070938 A/C cg13385521 chr17:29058706 SUZ12P 0.93 5.21 0.42 7.63e-7 Body mass index; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg10150615 chr22:24372951 LOC391322 0.82 7.12 0.54 7.87e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs67478160 0.634 rs2024669 chr14:104275602 G/C cg26031613 chr14:104095156 KLC1 -0.64 -6.42 -0.5 2.68e-9 Schizophrenia; TGCT cis rs4478858 0.735 rs12408524 chr1:31835853 A/G cg07478791 chr1:31886160 SERINC2 -0.47 -4.52 -0.38 1.43e-5 Alcohol dependence; TGCT cis rs40363 0.951 rs72778117 chr16:3531827 T/C cg00484396 chr16:3507460 NAT15 0.42 5.03 0.41 1.64e-6 Tuberculosis; TGCT cis rs10791323 0.569 rs10750553 chr11:133740251 T/C cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs478304 0.903 rs12293022 chr11:65531698 C/T cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.01e-7 Acne (severe); TGCT cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg21280719 chr6:42927975 GNMT -0.37 -4.59 -0.38 1.07e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6754311 0.628 rs309811 chr2:136625602 A/G cg07169764 chr2:136633963 MCM6 -0.63 -5.88 -0.47 3.51e-8 Mosquito bite size; TGCT cis rs12893668 0.644 rs12890820 chr14:104034849 T/C cg26031613 chr14:104095156 KLC1 -0.54 -4.45 -0.37 1.88e-5 Reticulocyte count; TGCT cis rs4938534 0.559 rs1944919 chr11:111259876 A/C cg01212326 chr11:111250286 POU2AF1 0.27 5.3 0.43 5.18e-7 Primary biliary cholangitis; TGCT cis rs4851254 0.626 rs13001783 chr2:100689652 A/T cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs2455799 0.593 rs13085352 chr3:15914845 T/C cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.68e-6 Mean platelet volume; TGCT cis rs11167764 1.000 rs7722567 chr5:141483178 C/T cg23435118 chr5:141488016 NDFIP1 -0.31 -5.09 -0.42 1.27e-6 Crohn's disease; TGCT cis rs1008375 1.000 rs60178264 chr4:17685308 G/T cg10189774 chr4:17578691 LAP3 0.52 4.74 0.39 5.82e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10946940 0.632 rs9366698 chr6:27672035 C/G cg10876282 chr6:28092338 ZSCAN16 0.52 4.77 0.39 5.02e-6 Systemic lupus erythematosus; TGCT cis rs7666738 0.791 rs60028147 chr4:99046618 G/A cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11105298 0.838 rs4842488 chr12:89881564 C/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs614226 1.000 rs1167725 chr12:120968559 A/T cg01236616 chr12:121019343 POP5 1.26 13.2 0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT trans rs7618501 0.602 rs9311446 chr3:50092226 G/A cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs9399137 0.507 rs7768278 chr6:135274957 T/C cg24558204 chr6:135376177 HBS1L 0.49 4.96 0.41 2.24e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs9291683 0.609 rs13149985 chr4:10028390 G/A cg00071950 chr4:10020882 SLC2A9 0.7 9.43 0.65 3.06e-16 Bone mineral density; TGCT cis rs12911832 1.000 rs4774310 chr15:58985164 T/G cg05156742 chr15:59063176 FAM63B 0.49 4.66 0.39 8.05e-6 Schizophrenia; TGCT cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg08859206 chr1:53392774 SCP2 0.34 4.93 0.4 2.63e-6 Monocyte count; TGCT cis rs11030122 0.635 rs10835540 chr11:4071429 T/A cg18678763 chr11:4115507 RRM1 -0.48 -5.61 -0.45 1.27e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs1949733 1.000 rs2631745 chr4:8490530 T/C cg11789530 chr4:8429930 ACOX3 -0.6 -5.5 -0.44 2.12e-7 Response to antineoplastic agents; TGCT cis rs477895 0.713 rs35095324 chr11:63948412 G/A cg04317338 chr11:64019027 PLCB3 0.78 6.43 0.5 2.53e-9 Mean platelet volume; TGCT cis rs769267 0.930 rs9917108 chr19:19572785 A/G cg08509172 chr19:19383838 TM6SF2 -0.35 -4.6 -0.38 1.02e-5 Tonsillectomy; TGCT cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg20999797 chr1:1681921 NA 0.18 4.67 0.39 7.67e-6 Body mass index; TGCT cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9913156 0.793 rs72835633 chr17:4562643 C/T cg19197139 chr17:4613644 ARRB2 0.86 7.9 0.58 1.32e-12 Lymphocyte counts; TGCT cis rs950169 1.000 rs79318564 chr15:84786150 G/A cg12863693 chr15:85201151 NMB 0.39 4.65 0.38 8.54e-6 Schizophrenia; TGCT cis rs2180341 0.824 rs9321076 chr6:127655614 G/A cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs1153858 0.832 rs1145078 chr15:45682277 C/T cg26924012 chr15:45694286 SPATA5L1 0.99 12.19 0.74 5.99e-23 Homoarginine levels; TGCT cis rs9427116 0.840 rs9427114 chr1:154626705 T/C cg17218026 chr1:154582156 ADAR 0.25 6.08 0.48 1.37e-8 Blood protein levels; TGCT cis rs875971 0.660 rs10263935 chr7:66096028 A/G cg00343986 chr7:65444356 GUSB 0.23 5.18 0.42 8.86e-7 Aortic root size; TGCT cis rs2721811 0.738 rs2521758 chr7:24762292 G/T cg17569154 chr7:24781545 DFNA5 0.21 4.6 0.38 1.01e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs10984561 1.000 rs10984561 chr9:122258577 C/T cg14242995 chr9:122249943 NA 0.59 5.53 0.44 1.84e-7 Pulmonary function decline; TGCT cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs617219 0.737 rs13158309 chr5:78463395 C/T cg09550809 chr5:78407562 BHMT -0.39 -5.49 -0.44 2.17e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7772486 0.754 rs4896841 chr6:146041522 T/C cg13319975 chr6:146136371 FBXO30 0.53 4.8 0.4 4.49e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6952808 0.689 rs4719391 chr7:2048136 T/C cg22963979 chr7:1858916 MAD1L1 -0.44 -6.93 -0.53 2.01e-10 Bipolar disorder and schizophrenia; TGCT cis rs941408 1.000 rs1640272 chr19:2800192 A/T cg06609049 chr19:2785107 THOP1 0.8 7.76 0.57 2.69e-12 Total cholesterol levels; TGCT cis rs6831352 0.725 rs2602846 chr4:100025151 T/A cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Alcohol dependence; TGCT cis rs7611238 0.560 rs6788868 chr3:195150694 G/A cg27323046 chr3:195102265 ACAP2 0.39 5.14 0.42 1.05e-6 Body mass index; TGCT cis rs9910055 0.529 rs228766 chr17:42186813 A/G cg19774624 chr17:42201019 HDAC5 0.71 6.57 0.51 1.23e-9 Total body bone mineral density; TGCT cis rs9868809 0.881 rs2276850 chr3:48669648 G/A cg00383909 chr3:49044727 WDR6 0.97 5.08 0.42 1.34e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9393692 0.905 rs34916901 chr6:26286149 G/T cg13736514 chr6:26305472 NA -0.41 -5.76 -0.46 6.12e-8 Educational attainment; TGCT cis rs2046867 0.954 rs6802796 chr3:72782740 T/A cg25664220 chr3:72788482 NA -0.55 -6.83 -0.52 3.42e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs72945132 0.882 rs67927691 chr11:70128786 C/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs826838 1.000 rs10875991 chr12:39108886 G/C cg13010199 chr12:38710504 ALG10B 0.82 6.78 0.52 4.27e-10 Heart rate; TGCT cis rs9911578 0.692 rs412000 chr17:56709058 G/C cg05425664 chr17:57184151 TRIM37 -0.49 -4.67 -0.39 7.63e-6 Intelligence (multi-trait analysis); TGCT cis rs9929218 0.906 rs33965787 chr16:68828173 G/A cg03880890 chr16:69439245 NA -0.22 -4.48 -0.37 1.68e-5 Colorectal cancer; TGCT cis rs7829975 0.500 rs7841082 chr8:8168987 C/T cg15556689 chr8:8085844 FLJ10661 -0.63 -5.73 -0.46 7.04e-8 Mood instability; TGCT cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg13695892 chr22:41940480 POLR3H 0.93 9.17 0.64 1.31e-15 Vitiligo; TGCT cis rs73198271 0.765 rs534103 chr8:8634069 A/G cg06636001 chr8:8085503 FLJ10661 -0.6 -4.45 -0.37 1.92e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.9 -6.56 -0.51 1.3e-9 Gut microbiome composition (summer); TGCT cis rs9309473 0.606 rs62149804 chr2:73837006 T/A cg07208825 chr2:73871855 ALMS1P 0.26 4.86 0.4 3.41e-6 Metabolite levels; TGCT cis rs651907 0.535 rs11707250 chr3:101509371 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.86 -10.47 -0.68 9.24e-19 Colorectal cancer; TGCT cis rs7172809 0.573 rs17470529 chr15:77673359 A/G cg22256960 chr15:77711686 NA -0.51 -4.79 -0.4 4.65e-6 Glucose homeostasis traits; TGCT cis rs10479542 0.721 rs6894113 chr5:178974789 G/C cg09060608 chr5:178986726 RUFY1 0.48 5.63 0.45 1.13e-7 Lung cancer; TGCT cis rs523522 0.962 rs3213565 chr12:120992401 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs7666738 0.830 rs7672901 chr4:98938781 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.652 rs553875 chr11:68695144 T/G cg04772025 chr11:68637568 NA 0.6 6.66 0.51 7.88e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs208520 0.690 rs851468 chr6:66825875 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.72 -0.69 2.28e-19 Exhaled nitric oxide output; TGCT cis rs7818382 0.967 rs7812465 chr8:96050557 C/T cg16049864 chr8:95962084 TP53INP1 0.6 7.4 0.55 1.84e-11 Alzheimer's disease (late onset); TGCT cis rs6089829 0.962 rs57684920 chr20:61662639 G/A cg02380750 chr20:61661411 NA -0.31 -5.22 -0.42 7.4e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs9926296 0.712 rs258332 chr16:89727683 G/A cg26513180 chr16:89883248 FANCA -0.67 -6.28 -0.49 5.19e-9 Vitiligo; TGCT cis rs9788682 1.000 rs12438181 chr15:78812098 G/A cg06917634 chr15:78832804 PSMA4 -0.68 -4.96 -0.41 2.27e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs12682352 0.715 rs332039 chr8:8723651 C/G cg06636001 chr8:8085503 FLJ10661 0.63 5.84 0.46 4.26e-8 Neuroticism; TGCT cis rs10501293 0.675 rs7949021 chr11:43004134 A/G cg03447554 chr11:43094025 NA 0.44 6.39 0.5 3.03e-9 Cognitive performance; TGCT cis rs6570726 0.791 rs11155426 chr6:145817130 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs151997 0.925 rs27624 chr5:50167662 C/T cg06027927 chr5:50259733 NA 0.47 4.77 0.39 5e-6 Callous-unemotional behaviour; TGCT cis rs1865760 0.622 rs9295685 chr6:26071725 G/C cg17042849 chr6:26104293 HIST1H4C -0.62 -5.33 -0.43 4.56e-7 Height; TGCT cis rs3733585 0.699 rs6449179 chr4:9969117 G/A cg11266682 chr4:10021025 SLC2A9 -0.59 -7.85 -0.58 1.7e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4664308 0.870 rs55959207 chr2:161016981 A/C cg03641300 chr2:160917029 PLA2R1 -0.27 -6.89 -0.53 2.48e-10 Idiopathic membranous nephropathy; TGCT cis rs7547997 0.615 rs114657189 chr1:158318340 G/C cg03528325 chr1:158223921 CD1A 0.33 4.81 0.4 4.38e-6 QRS duration; TGCT cis rs13191362 1.000 rs67042566 chr6:163006541 A/T cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12681287 0.640 rs13253261 chr8:87458500 T/C cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs4072705 0.615 rs4838189 chr9:127248926 C/A cg13476313 chr9:127244764 NR5A1 0.3 4.98 0.41 2.05e-6 Menarche (age at onset); TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg12419862 chr22:24373484 LOC391322 0.84 7.99 0.58 7.84e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4689388 0.926 rs4343789 chr4:6285228 C/G cg25554036 chr4:6271136 WFS1 0.56 8.15 0.59 3.3e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12477438 0.520 rs11677247 chr2:99756358 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs546131 1.000 rs546131 chr11:34851760 G/C cg06937548 chr11:34938143 PDHX;APIP 0.63 5.61 0.45 1.27e-7 Lung disease severity in cystic fibrosis; TGCT cis rs610932 0.517 rs588084 chr11:59973059 C/T cg18570331 chr11:60101691 MS4A6E 0.52 4.79 0.4 4.6e-6 Alzheimer's disease; TGCT cis rs2692947 0.673 rs2229169 chr2:96780716 T/G cg23100626 chr2:96804247 ASTL -0.44 -5.21 -0.42 7.78e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg14820908 chr5:178986412 RUFY1 -0.59 -6.36 -0.5 3.51e-9 Lung cancer; TGCT cis rs2404602 0.647 rs7165053 chr15:76978918 A/G cg23625390 chr15:77176239 SCAPER -0.39 -4.93 -0.41 2.53e-6 Blood metabolite levels; TGCT cis rs3096299 0.586 rs4572400 chr16:89533516 T/A cg06640241 chr16:89574553 SPG7 0.72 7.31 0.55 2.94e-11 Multiple myeloma (IgH translocation); TGCT cis rs887829 0.569 rs4663967 chr2:234653184 A/C cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.61 -0.38 9.83e-6 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs10751667 1.000 rs10794357 chr11:973374 T/C cg06064525 chr11:970664 AP2A2 -0.31 -6.25 -0.49 5.89e-9 Alzheimer's disease (late onset); TGCT cis rs1729951 0.575 rs361241 chr3:136699561 C/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs1372520 0.935 rs2245801 chr4:90757840 T/C cg14346243 chr4:90757452 SNCA -0.58 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs597539 0.652 rs513615 chr11:68705504 G/T cg21963583 chr11:68658836 MRPL21 0.39 6.41 0.5 2.78e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs916888 0.773 rs199443 chr17:44819565 C/T cg15921436 chr17:44337874 NA 0.56 7.75 0.57 2.88e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs71597109 0.639 rs35194352 chr4:102726594 T/C cg14855874 chr4:102712397 BANK1 0.41 4.72 0.39 6.16e-6 Chronic lymphocytic leukemia; TGCT cis rs12497850 0.864 rs7431857 chr3:48900347 G/A cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs68170813 0.523 rs75999022 chr7:107017135 C/T cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs1670533 1.000 rs2045065 chr4:1052488 A/G cg20887711 chr4:1340912 KIAA1530 0.67 5.2 0.42 7.86e-7 Recombination rate (females); TGCT cis rs875971 0.862 rs57866200 chr7:65565392 A/G cg11764359 chr7:65958608 NA -0.56 -4.82 -0.4 4.1e-6 Aortic root size; TGCT cis rs908922 0.676 rs2146120 chr1:152504200 A/T cg20991723 chr1:152506922 NA 0.44 5.94 0.47 2.66e-8 Hair morphology; TGCT cis rs986417 0.901 rs4901987 chr14:60987529 C/T cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs2204008 0.714 rs11520135 chr12:38114863 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.56 0.56 7.76e-12 Bladder cancer; TGCT cis rs2228479 0.850 rs2238525 chr16:89809902 T/C cg26513180 chr16:89883248 FANCA 0.78 4.5 0.37 1.56e-5 Skin colour saturation; TGCT cis rs9457247 1.000 rs422094 chr6:167397033 C/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.88 -0.4 3.17e-6 Crohn's disease; TGCT cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg27121462 chr16:89883253 FANCA 0.61 5.81 0.46 4.86e-8 Vitiligo; TGCT cis rs12135894 0.648 rs4648423 chr1:3765678 C/T cg10555106 chr1:3691387 LOC388588 -0.3 -4.59 -0.38 1.07e-5 Mean corpuscular volume; TGCT cis rs826838 0.935 rs1486357 chr12:39073675 A/G cg26384229 chr12:38710491 ALG10B 1.06 10.35 0.68 1.74e-18 Heart rate; TGCT cis rs9814567 1.000 rs9289471 chr3:134230811 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3809566 1.000 rs4774471 chr15:63332645 A/T cg05507819 chr15:63340323 TPM1 -0.5 -4.64 -0.38 8.7e-6 Platelet count; TGCT cis rs4523957 0.583 rs7503141 chr17:2044645 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1552244 0.608 rs7615408 chr3:10000186 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.32 -4.86 -0.4 3.55e-6 Alzheimer's disease; TGCT cis rs3733585 0.605 rs4697708 chr4:10121189 A/G cg00071950 chr4:10020882 SLC2A9 -0.51 -5.29 -0.43 5.41e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs910316 1.000 rs1047418 chr14:75605792 A/G cg11812906 chr14:75593930 NEK9 0.73 7.23 0.54 4.34e-11 Height; TGCT cis rs3540 0.960 rs7167704 chr15:90956801 G/T cg22089800 chr15:90895588 ZNF774 0.79 7.77 0.57 2.59e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7119 0.637 rs12913005 chr15:77856571 T/A cg27398640 chr15:77910606 LINGO1 -0.27 -4.92 -0.4 2.66e-6 Type 2 diabetes; TGCT cis rs734999 0.566 rs6424092 chr1:2532899 C/A cg18854424 chr1:2615690 NA -0.44 -5.1 -0.42 1.22e-6 Ulcerative colitis; TGCT cis rs732765 0.734 rs12323528 chr14:75152068 G/T cg06637938 chr14:75390232 RPS6KL1 -0.57 -4.82 -0.4 4.15e-6 Non-small cell lung cancer; TGCT cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg08645402 chr16:4508243 NA 0.19 5.3 0.43 5.14e-7 Schizophrenia; TGCT cis rs2075671 0.903 rs4727459 chr7:100276821 T/C cg20848291 chr7:100343083 ZAN -0.52 -4.56 -0.38 1.21e-5 Other erythrocyte phenotypes; TGCT cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg22105103 chr4:187893119 NA 0.35 4.89 0.4 3.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs61990749 0.597 rs176952 chr14:78180736 T/C cg23188588 chr14:78226832 SNW1;C14orf178 0.66 4.65 0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg09177884 chr7:1199841 ZFAND2A -0.51 -4.89 -0.4 3.06e-6 Longevity;Endometriosis; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg12419862 chr22:24373484 LOC391322 0.89 7.86 0.58 1.55e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs4660261 0.526 rs2485996 chr1:44354661 C/T cg13606994 chr1:44402422 ARTN -0.41 -4.46 -0.37 1.82e-5 Intelligence (multi-trait analysis); TGCT cis rs694739 0.628 rs10897487 chr11:64140704 C/T cg23796481 chr11:64053134 BAD;GPR137 0.63 6.54 0.51 1.44e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs1865760 0.865 rs6929805 chr6:25950834 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT cis rs881375 0.967 rs1930780 chr9:123686219 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.47 0.44 2.35e-7 Rheumatoid arthritis; TGCT cis rs2361718 0.521 rs2361724 chr17:78099114 G/A cg02096758 chr17:77394895 HRNBP3 0.24 4.64 0.38 8.9e-6 Yeast infection; TGCT cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs3096299 0.685 rs4785675 chr16:89539974 T/C cg08392591 chr16:89556376 ANKRD11 0.57 5.4 0.44 3.2e-7 Multiple myeloma (IgH translocation); TGCT cis rs7914558 1.000 rs10748838 chr10:104943986 T/A cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.65e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs896854 0.517 rs1011796 chr8:95951273 A/G cg16049864 chr8:95962084 TP53INP1 0.55 6.13 0.48 1.07e-8 Type 2 diabetes; TGCT cis rs709400 0.663 rs55723020 chr14:103991401 G/A cg26031613 chr14:104095156 KLC1 0.88 9.39 0.64 3.88e-16 Body mass index; TGCT cis rs782590 0.967 rs6545506 chr2:55798108 A/G cg18811423 chr2:55921094 PNPT1 -0.64 -6.9 -0.53 2.39e-10 Metabolic syndrome; TGCT cis rs4242434 0.672 rs10110443 chr8:22484296 C/G cg03733263 chr8:22462867 KIAA1967 0.97 13.6 0.77 2.44e-26 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg11494091 chr17:61959527 GH2 0.61 14.46 0.79 2.18e-28 Prudent dietary pattern; TGCT cis rs62103177 0.810 rs62103175 chr18:77622467 C/T cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs3087591 0.708 rs2854319 chr17:29694054 G/C cg24425628 chr17:29625626 OMG;NF1 0.39 5.65 0.45 1.03e-7 Hip circumference; TGCT cis rs9972944 0.729 rs1895035 chr17:63777711 G/A cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg16590910 chr6:42928470 GNMT -0.49 -4.52 -0.38 1.41e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12477438 0.748 rs10200974 chr2:99675227 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs60154123 0.505 rs2206043 chr1:210042983 G/A cg23283495 chr1:209979779 IRF6 0.67 4.99 0.41 1.96e-6 Coronary artery disease; TGCT cis rs2013441 1.000 rs2526472 chr17:20137888 G/A cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs7917772 0.582 rs7075269 chr10:104365724 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs763014 0.931 rs1981483 chr16:630665 G/A cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg04944784 chr2:26401820 FAM59B -0.76 -6.34 -0.49 3.94e-9 Gut microbiome composition (summer); TGCT trans rs2970818 0.831 rs7304949 chr12:4609625 A/G cg03807737 chr6:44242160 TMEM151B 0.31 7.54 0.56 8.47e-12 Phosphorus levels; TGCT cis rs892961 0.836 rs8071497 chr17:75414358 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.71 0.52 6.16e-10 Airflow obstruction; TGCT cis rs9921192 1.000 rs251734 chr16:4321441 A/G cg00021532 chr16:4324280 TFAP4 0.84 9.73 0.66 5.68e-17 Prostate-specific antigen levels; TGCT cis rs3812831 0.662 rs418027 chr13:114929344 A/C cg06611532 chr13:114900021 NA 0.35 6.28 0.49 5.16e-9 Schizophrenia; TGCT cis rs2576037 0.583 rs9960463 chr18:44522808 T/A cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.71 -0.39 6.41e-6 Personality dimensions; TGCT cis rs9309473 0.500 rs2421582 chr2:73898420 A/G cg20560298 chr2:73613845 ALMS1 0.41 4.51 0.38 1.46e-5 Metabolite levels; TGCT cis rs7772486 0.658 rs9403737 chr6:145962193 G/T cg05347473 chr6:146136440 FBXO30 0.5 4.71 0.39 6.65e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.822 rs9992360 chr4:98937123 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 1.000 rs9897206 chr17:28406108 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -6.77 -0.52 4.47e-10 Coffee consumption (cups per day); TGCT cis rs116095464 0.614 rs56299325 chr5:220594 C/T cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs9549367 0.774 rs2287246 chr13:113889127 A/G cg00898013 chr13:113819073 PROZ -0.4 -4.92 -0.4 2.7e-6 Platelet distribution width; TGCT cis rs1799949 1.000 rs12952790 chr17:41299607 A/G cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs9788682 0.747 rs7177514 chr15:78907406 C/G cg24631222 chr15:78858424 CHRNA5 0.78 5.71 0.46 8.03e-8 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs713587 0.571 rs546217 chr2:25311537 A/C cg01884057 chr2:25150051 NA -0.25 -4.81 -0.4 4.36e-6 Body mass index in non-asthmatics; TGCT cis rs933688 1.000 rs12651840 chr5:90729592 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 8.86 0.62 7.17e-15 Smoking behavior; TGCT cis rs7786808 0.579 rs4045391 chr7:158181826 T/C cg01191920 chr7:158217561 PTPRN2 -0.34 -5.06 -0.41 1.45e-6 Obesity-related traits; TGCT cis rs9303542 0.559 rs35621842 chr17:46606222 C/T cg25032089 chr17:46643351 HOXB3 0.57 5.58 0.45 1.46e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg03161606 chr19:29218774 NA 0.56 6.1 0.48 1.26e-8 Methadone dose in opioid dependence; TGCT trans rs877282 0.898 rs12358966 chr10:758703 A/G cg22713356 chr15:30763199 NA 1.12 8.42 0.6 7.78e-14 Uric acid levels; TGCT cis rs1008375 0.900 rs6851783 chr4:17578469 A/G cg16339924 chr4:17578868 LAP3 0.83 7.06 0.54 1.04e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2718798 1 rs2718798 chr3:133492088 A/C cg08048268 chr3:133502702 NA -0.45 -5.89 -0.47 3.33e-8 Ankle injury; TGCT cis rs6952808 0.636 rs73048162 chr7:1949328 T/C cg04267008 chr7:1944627 MAD1L1 -0.36 -4.72 -0.39 6.34e-6 Bipolar disorder and schizophrenia; TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg06493612 chr6:15502050 JARID2 0.65 5.38 0.44 3.51e-7 Gambling; TGCT cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg20607798 chr8:58055168 NA 0.65 5.43 0.44 2.86e-7 Developmental language disorder (linguistic errors); TGCT cis rs7818688 0.697 rs11780130 chr8:95976083 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs854765 0.647 rs6502637 chr17:17986098 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.68 7.01 0.53 1.33e-10 Total body bone mineral density; TGCT cis rs13191362 0.935 rs13215748 chr6:163010710 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs9894429 0.752 rs6565610 chr17:79592652 A/G cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs1784581 0.588 rs7453474 chr6:162421736 C/T cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.08e-9 Itch intensity from mosquito bite; TGCT cis rs6598955 0.671 rs12085416 chr1:26627835 T/C cg04990556 chr1:26633338 UBXN11 0.67 5.44 0.44 2.77e-7 Obesity-related traits; TGCT trans rs9388451 0.807 rs1269175 chr6:126040435 A/G cg05039488 chr6:79577232 IRAK1BP1 0.74 7.56 0.56 7.71e-12 Brugada syndrome; TGCT cis rs929354 0.772 rs1182442 chr7:157026633 G/A cg05182265 chr7:156933206 UBE3C 0.4 9.0 0.63 3.25e-15 Body mass index; TGCT cis rs7010267 0.570 rs6469798 chr8:120018291 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs10782582 0.617 rs1846233 chr1:76159354 C/T cg03433033 chr1:76189801 ACADM -0.65 -7.41 -0.55 1.67e-11 Daytime sleep phenotypes; TGCT cis rs11190604 1.000 rs2489043 chr10:102334327 T/C cg16342193 chr10:102329863 NA -0.4 -5.08 -0.42 1.32e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs595982 0.527 rs73061658 chr19:49372376 G/C cg21252483 chr19:49399788 TULP2 -0.42 -6.36 -0.5 3.58e-9 Red cell distribution width; TGCT cis rs595982 0.527 rs73061656 chr19:49372355 G/A cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.16 -0.64 1.35e-15 Red cell distribution width; TGCT cis rs1153858 1.000 rs12593230 chr15:45646968 A/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs473651 0.935 rs483166 chr2:239346641 C/T cg21699342 chr2:239360505 ASB1 -0.17 -4.78 -0.39 4.78e-6 Multiple system atrophy; TGCT cis rs57994353 0.802 rs12002854 chr9:139377499 G/A cg13741927 chr9:139327495 INPP5E -0.23 -5.16 -0.42 9.54e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs17270561 0.723 rs12192635 chr6:25880907 A/T cg16482183 chr6:26056742 HIST1H1C 0.86 6.55 0.51 1.4e-9 Iron status biomarkers; TGCT cis rs200810 0.656 rs17752324 chr6:98025365 C/T cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.65 -4.47 -0.37 1.71e-5 Body mass index; TGCT cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg23758822 chr17:41437982 NA 0.72 6.9 0.53 2.33e-10 Menopause (age at onset); TGCT cis rs3733631 1.000 rs10014175 chr4:104659515 T/A cg24090629 chr4:104641072 TACR3 -0.73 -6.03 -0.48 1.76e-8 Menarche (age at onset); TGCT cis rs1865760 0.929 rs12195653 chr6:25958621 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.25 0.49 6.04e-9 Height; TGCT cis rs7726839 0.574 rs11134149 chr5:637277 A/G cg09021430 chr5:549028 NA -0.34 -4.99 -0.41 1.99e-6 Obesity-related traits; TGCT cis rs7937682 0.961 rs1784784 chr11:111483185 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -9.76 -0.66 4.76e-17 Primary sclerosing cholangitis; TGCT cis rs7044106 0.791 rs4836829 chr9:123482747 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.95 0.41 2.37e-6 Hip circumference adjusted for BMI; TGCT cis rs1372520 0.684 rs2619368 chr4:90729747 T/G cg20003494 chr4:90757398 SNCA -0.66 -5.21 -0.42 7.59e-7 Neuroticism; TGCT cis rs4730250 0.707 rs257372 chr7:106796977 T/G cg02696742 chr7:106810147 HBP1 -0.72 -5.89 -0.47 3.44e-8 Osteoarthritis; TGCT trans rs9951602 0.512 rs9958376 chr18:76655167 G/T cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs2458413 0.563 rs2458422 chr8:105332817 C/T cg04554929 chr8:105342491 NA -0.61 -9.81 -0.66 3.55e-17 Paget's disease; TGCT cis rs524023 0.915 rs531763 chr11:64352063 A/G cg07733098 chr11:64478343 NRXN2 -0.31 -4.63 -0.38 9.14e-6 Urate levels in obese individuals; TGCT cis rs1568889 0.838 rs4572130 chr11:28371794 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.91 10.24 0.68 3.31e-18 Bipolar disorder; TGCT cis rs8180040 0.932 rs12490058 chr3:47529063 T/C cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs916888 0.821 rs199505 chr17:44859410 A/G cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs13102973 0.931 rs13134190 chr4:135854932 T/C cg14419869 chr4:135874104 NA 0.23 4.58 0.38 1.12e-5 Subjective well-being; TGCT cis rs9560113 0.959 rs4773385 chr13:112178452 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT trans rs4650994 0.524 rs2476558 chr1:178580953 C/T cg05059571 chr16:84539110 KIAA1609 0.52 10.34 0.68 1.85e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs12142240 0.667 rs12062 chr1:46830447 G/T cg14993813 chr1:46806288 NSUN4 0.57 4.8 0.4 4.54e-6 Menopause (age at onset); TGCT cis rs8077889 0.645 rs1230396 chr17:41843029 A/C cg26893861 chr17:41843967 DUSP3 -1.15 -21.87 -0.89 2.21e-44 Triglycerides; TGCT cis rs7829975 0.774 rs35039922 chr8:8675325 A/T cg08975724 chr8:8085496 FLJ10661 0.54 4.79 0.4 4.63e-6 Mood instability; TGCT cis rs514406 0.679 rs960570 chr1:53237763 A/G cg16325326 chr1:53192061 ZYG11B -0.58 -6.41 -0.5 2.75e-9 Monocyte count; TGCT cis rs9640161 0.750 rs11765644 chr7:150026339 C/G cg10018233 chr7:150070692 REPIN1 0.32 4.61 0.38 9.67e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs7618915 0.501 rs12486554 chr3:52742537 A/T cg07507251 chr3:52567010 NT5DC2 0.48 6.76 0.52 4.9e-10 Bipolar disorder; TGCT cis rs7772486 0.875 rs1331637 chr6:146337087 T/C cg23711669 chr6:146136114 FBXO30 0.88 9.67 0.66 7.78e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.620 rs2591967 chr5:56233551 C/G cg12311346 chr5:56204834 C5orf35 0.57 6.13 0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs9611565 0.592 rs57102627 chr22:41987627 T/C cg13695892 chr22:41940480 POLR3H -0.83 -7.82 -0.57 1.94e-12 Vitiligo; TGCT cis rs4803468 0.967 rs2304243 chr19:41942708 C/G cg09537434 chr19:41945824 ATP5SL 0.91 10.21 0.68 3.82e-18 Height; TGCT cis rs67311347 1.000 rs2276871 chr3:40499273 C/T cg17264618 chr3:40429014 ENTPD3 0.31 4.48 0.37 1.7e-5 Renal cell carcinoma; TGCT cis rs35146811 0.659 rs863450 chr7:99821685 C/T cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg01585852 chr22:24235823 MIF -0.22 -4.7 -0.39 6.78e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9389248 0.690 rs728030 chr6:135246294 G/T cg22676075 chr6:135203613 NA -0.48 -4.82 -0.4 4.1e-6 High light scatter reticulocyte percentage of red cells; TGCT trans rs561341 1.000 rs1557731 chr17:30321567 T/G cg20587970 chr11:113659929 NA -1.05 -13.02 -0.76 5.98e-25 Hip circumference adjusted for BMI; TGCT cis rs7666738 0.830 rs1869082 chr4:98841254 T/A cg17366294 chr4:99064904 C4orf37 0.72 7.5 0.56 1.07e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 0.778 rs2592115 chr2:233736349 C/T cg08000102 chr2:233561755 GIGYF2 -0.44 -4.45 -0.37 1.87e-5 Coronary artery disease; TGCT cis rs4711350 1.000 rs4711350 chr6:33741716 A/G cg18005901 chr6:33739558 LEMD2 -0.55 -5.87 -0.47 3.73e-8 Schizophrenia; TGCT cis rs8002180 0.959 rs1970477 chr13:95921204 C/T cg24476569 chr13:95954382 ABCC4 0.39 4.97 0.41 2.2e-6 Blood metabolite levels; TGCT cis rs7121446 0.512 rs7111523 chr11:121897397 A/G cg22813542 chr11:121986974 LOC399959;BLID -0.48 -4.59 -0.38 1.08e-5 Cardiovascular risk factors (age interaction); TGCT cis rs6684514 0.922 rs12037778 chr1:156284864 A/G cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs35160687 0.865 rs10189492 chr2:86478902 G/A cg12542933 chr2:85804724 VAMP8 0.4 4.82 0.4 4.16e-6 Night sleep phenotypes; TGCT cis rs12220898 0.749 rs2377976 chr10:50479493 A/G cg06072769 chr10:50146962 WDFY4 0.37 4.89 0.4 3.03e-6 Inflammatory biomarkers; TGCT cis rs2243480 1.000 rs316331 chr7:65604622 A/G cg07424592 chr7:64974309 NA -1.27 -7.96 -0.58 9.33e-13 Diabetic kidney disease; TGCT cis rs8141529 0.687 rs6005867 chr22:29165120 T/C cg02153584 chr22:29168773 CCDC117 0.71 6.18 0.49 8.58e-9 Lymphocyte counts; TGCT cis rs10992471 0.627 rs4744138 chr9:95291909 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.36 -0.43 3.99e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2033711 0.783 rs8113810 chr19:58932106 A/G cg13877915 chr19:58951672 ZNF132 0.88 11.09 0.71 2.83e-20 Uric acid clearance; TGCT cis rs1975974 1.000 rs7210944 chr17:21727476 C/T cg18423549 chr17:21743878 NA -0.56 -5.12 -0.42 1.11e-6 Psoriasis; TGCT cis rs9549367 0.756 rs9603814 chr13:113900782 C/T cg18105134 chr13:113819100 PROZ 0.34 5.76 0.46 6.38e-8 Platelet distribution width; TGCT cis rs826838 1.000 rs10875717 chr12:38911174 T/C cg26384229 chr12:38710491 ALG10B 1.01 9.84 0.66 3.01e-17 Heart rate; TGCT cis rs12971120 0.947 rs7241558 chr18:72169267 A/T cg25817165 chr18:72167213 CNDP2 -0.3 -5.61 -0.45 1.28e-7 Refractive error; TGCT trans rs72772090 1.000 rs56116814 chr5:96048714 G/A cg17670890 chr5:176011783 PCDH24 0.37 6.62 0.51 9.8e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7588654 1.000 rs72613757 chr2:219968869 G/A cg19394737 chr2:219892361 CCDC108 -0.35 -4.55 -0.38 1.27e-5 Height; TGCT cis rs3027009 0.881 rs3026955 chr1:159144034 C/A cg24432768 chr1:158149974 CD1D -0.55 -4.76 -0.39 5.41e-6 Lean body mass and age at menarche (combined); TGCT cis rs2439831 1.000 rs565007 chr15:43716641 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs9911578 1.000 rs3744108 chr17:56585872 G/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.26 -0.64 7.9e-16 Intelligence (multi-trait analysis); TGCT cis rs1153858 1.000 rs4627277 chr15:45652768 C/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.49 5.14 0.42 1.02e-6 Lymphocyte counts; TGCT cis rs4711350 0.765 rs943473 chr6:33743651 G/C cg18005901 chr6:33739558 LEMD2 -0.59 -6.72 -0.52 5.99e-10 Schizophrenia; TGCT cis rs9318086 0.648 rs7330140 chr13:24473074 A/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.82 8.98 0.63 3.58e-15 Myopia (pathological); TGCT cis rs3020333 0.755 rs1293935 chr6:152017958 C/G cg22157087 chr6:152012887 ESR1 0.24 6.18 0.49 8.44e-9 Total body bone mineral density; TGCT cis rs8179 0.645 rs6954221 chr7:92283262 A/G cg15732164 chr7:92237376 CDK6 0.29 5.05 0.41 1.57e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs412000 0.560 rs4793583 chr17:56451407 A/C cg12560992 chr17:57184187 TRIM37 -0.71 -7.5 -0.56 1.05e-11 Primary tooth development (time to first tooth eruption); TGCT cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg11644478 chr21:40555479 PSMG1 1.04 10.72 0.69 2.25e-19 Cognitive function; TGCT cis rs1964356 0.967 rs2953802 chr8:8851881 G/A cg15556689 chr8:8085844 FLJ10661 0.73 6.57 0.51 1.27e-9 Mean corpuscular volume; TGCT cis rs10908458 0.584 rs10908455 chr1:155067283 C/T cg23973274 chr1:155060172 NA 0.27 5.11 0.42 1.21e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs5769707 0.632 rs5770601 chr22:50021903 A/G cg06623630 chr22:50017776 C22orf34 -0.29 -4.86 -0.4 3.48e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs137699 1.000 rs5757630 chr22:39754433 G/T cg24399712 chr22:39784796 NA -0.65 -5.64 -0.45 1.11e-7 IgG glycosylation; TGCT cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg16414030 chr3:133502952 NA 0.66 11.1 0.71 2.65e-20 Iron status biomarkers; TGCT cis rs2836974 0.545 rs8128901 chr21:40710419 G/A cg11890956 chr21:40555474 PSMG1 0.78 7.81 0.57 2.02e-12 Cognitive function; TGCT cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg22535103 chr8:58192502 C8orf71 -0.4 -5.06 -0.41 1.44e-6 Developmental language disorder (linguistic errors); TGCT cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg22800045 chr5:56110881 MAP3K1 0.53 4.43 0.37 2.01e-5 Initial pursuit acceleration; TGCT cis rs6076065 0.630 rs2424558 chr20:23429344 A/G cg11657817 chr20:23433608 CST11 0.34 6.11 0.48 1.2e-8 Facial morphology (factor 15, philtrum width); TGCT cis rs57590327 0.503 rs1461611 chr3:81512061 C/A cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg15659132 chr6:26577336 NA -0.88 -10.64 -0.69 3.47e-19 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.810 rs2919470 chr8:101233301 C/A cg06636551 chr8:101224915 SPAG1 0.53 7.24 0.54 4.19e-11 Atrioventricular conduction; TGCT cis rs7617773 0.747 rs34076262 chr3:48370416 C/T cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs986417 0.818 rs761557 chr14:61077484 C/T cg24736989 chr14:60973904 NA 0.68 4.44 0.37 2e-5 Gut microbiota (bacterial taxa); TGCT cis rs9952991 0.566 rs657555 chr18:12847136 C/T cg23598886 chr18:12777645 NA 0.58 5.16 0.42 9.54e-7 Inflammatory skin disease; TGCT cis rs7089973 0.604 rs8181444 chr10:116588981 C/T cg03647239 chr10:116582469 FAM160B1 0.59 5.75 0.46 6.46e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs3764563 1.000 rs2283603 chr19:15731128 T/C cg20725493 chr19:15740067 CYP4F8 -0.43 -4.68 -0.39 7.26e-6 Inflammatory biomarkers; TGCT cis rs9527 0.668 rs7092815 chr10:104736345 G/T cg15744005 chr10:104629667 AS3MT -0.44 -5.02 -0.41 1.79e-6 Arsenic metabolism; TGCT cis rs17102423 0.964 rs11627859 chr14:65602384 G/A cg11161011 chr14:65562177 MAX -0.49 -6.7 -0.52 6.46e-10 Obesity-related traits; TGCT trans rs6740731 0.518 rs16823846 chr2:145299944 C/T cg03855592 chr7:113034122 NA 0.41 6.71 0.52 6.33e-10 Coronary artery disease; TGCT cis rs9486719 1.000 rs28623445 chr6:96899116 G/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs140364877 1 rs140364877 chr7:1885178 C/T cg22963979 chr7:1858916 MAD1L1 -0.32 -4.8 -0.4 4.57e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg22166914 chr1:53195759 ZYG11B -0.36 -5.93 -0.47 2.78e-8 Monocyte count; TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg27535305 chr1:53392650 SCP2 -0.23 -4.62 -0.38 9.41e-6 Monocyte count; TGCT cis rs10779751 0.770 rs11581010 chr1:11212458 A/G cg08854313 chr1:11322531 MTOR -0.83 -6.46 -0.5 2.16e-9 Body mass index; TGCT cis rs1801251 1.000 rs11676216 chr2:233706368 C/T cg25237894 chr2:233734115 C2orf82 -0.33 -5.94 -0.47 2.71e-8 Coronary artery disease; TGCT cis rs7208859 0.623 rs56378576 chr17:29010120 C/T cg13385521 chr17:29058706 SUZ12P 0.75 4.51 0.38 1.5e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6121246 0.697 rs6060912 chr20:30325755 C/A cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs2228479 0.557 rs11641726 chr16:89891619 G/A cg06558623 chr16:89946397 TCF25 0.55 4.79 0.4 4.69e-6 Skin colour saturation; TGCT cis rs4148883 0.603 rs1893883 chr4:100124716 C/G cg12011299 chr4:100065546 ADH4 0.37 5.47 0.44 2.36e-7 Alcohol dependence; TGCT cis rs7666738 0.830 rs28416660 chr4:98899525 C/G cg05340658 chr4:99064831 C4orf37 0.51 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1355223 0.583 rs2941057 chr11:34882220 G/A cg11058730 chr11:34937778 PDHX;APIP 0.8 8.94 0.63 4.49e-15 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg17747265 chr1:1875780 NA -0.37 -7.04 -0.53 1.14e-10 Body mass index; TGCT cis rs4455778 0.860 rs6973983 chr7:49069524 T/A cg26309511 chr7:48887640 NA 0.45 5.32 0.43 4.78e-7 Lung cancer in never smokers; TGCT trans rs12339966 0.653 rs11795038 chr9:11285121 T/G cg03488587 chr11:64876988 C11orf2 0.3 6.7 0.52 6.5e-10 Systolic blood pressure; TGCT trans rs1415174 0.916 rs7537916 chr1:87852384 A/T cg23065576 chr20:25207247 ENTPD6 -0.25 -6.66 -0.51 8.09e-10 Breast cancer; TGCT cis rs826838 0.967 rs826870 chr12:39120250 G/A cg13010199 chr12:38710504 ALG10B -0.64 -5.07 -0.41 1.39e-6 Heart rate; TGCT cis rs7809950 1.000 rs10274041 chr7:107261556 C/T cg23024343 chr7:107201750 COG5 0.36 5.63 0.45 1.15e-7 Coronary artery disease; TGCT cis rs427394 1.000 rs427394 chr5:6745875 A/G cg10857441 chr5:6722123 POLS -0.29 -6.93 -0.53 2.07e-10 Menopause (age at onset); TGCT cis rs295140 0.535 rs35417285 chr2:201233040 T/C cg04283868 chr2:201171347 SPATS2L 0.52 4.99 0.41 2.02e-6 QT interval; TGCT cis rs7927592 0.546 rs497261 chr11:68192244 T/C cg16797656 chr11:68205561 LRP5 0.29 4.97 0.41 2.16e-6 Total body bone mineral density; TGCT cis rs7246657 0.943 rs4969487 chr19:37831039 C/T cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs1994135 0.669 rs11052747 chr12:33697913 C/G cg06521331 chr12:34319734 NA -0.31 -4.81 -0.4 4.32e-6 Resting heart rate; TGCT cis rs56104184 0.775 rs73061689 chr19:49397214 C/T cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7833790 0.724 rs12676336 chr8:82771008 C/T cg27398817 chr8:82754497 SNX16 0.69 5.52 0.44 1.9e-7 Diastolic blood pressure; TGCT cis rs12210905 1.000 rs72843629 chr6:27175215 G/T cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs61990749 0.597 rs12887606 chr14:78200620 G/A cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs4499344 0.730 rs421607 chr19:33104951 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.76 0.62 1.23e-14 Mean platelet volume; TGCT trans rs11088226 0.645 rs2833917 chr21:33957544 C/T cg09050820 chr6:167586206 TCP10L2 0.74 6.96 0.53 1.71e-10 Gastritis; TGCT cis rs7611238 0.560 rs7611090 chr3:195025180 T/G cg27323046 chr3:195102265 ACAP2 0.37 4.89 0.4 3.12e-6 Body mass index; TGCT trans rs7618501 0.521 rs952594 chr3:49908023 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.85 8.84 0.62 7.83e-15 Intelligence (multi-trait analysis); TGCT cis rs72843506 0.722 rs78477504 chr17:20138347 C/T cg18979559 chr17:20280153 CCDC144C -0.65 -4.88 -0.4 3.2e-6 Schizophrenia; TGCT cis rs9549367 0.713 rs3024743 chr13:113821430 C/T cg09473364 chr13:112927190 NA -0.3 -4.47 -0.37 1.71e-5 Platelet distribution width; TGCT cis rs896854 0.738 rs481887 chr8:95967838 A/G cg09323728 chr8:95962352 TP53INP1 0.45 5.08 0.42 1.33e-6 Type 2 diabetes; TGCT cis rs11711311 0.911 rs9817327 chr3:113478500 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs7219021 0.705 rs11079842 chr17:47002762 G/A cg26022315 chr17:47021804 SNF8 -0.54 -4.65 -0.39 8.2e-6 Schizophrenia or bipolar disorder; TGCT cis rs28595532 0.920 rs115994609 chr4:119777273 G/A cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs597539 0.580 rs7935851 chr11:68731122 A/G cg06112835 chr11:68658793 MRPL21 0.45 7.43 0.56 1.54e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13082711 0.522 rs543882 chr3:27331854 T/C cg02860705 chr3:27208620 NA 0.34 5.7 0.46 8.16e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs539096 0.624 rs499257 chr1:44078384 T/C cg12908607 chr1:44402522 ARTN -0.44 -4.86 -0.4 3.55e-6 Intelligence (multi-trait analysis); TGCT cis rs60154123 0.505 rs77990373 chr1:210041111 T/C cg12034118 chr1:209979487 IRF6 0.65 4.56 0.38 1.2e-5 Coronary artery disease; TGCT cis rs546131 0.928 rs547504 chr11:34847225 G/T cg11058730 chr11:34937778 PDHX;APIP 0.58 5.17 0.42 8.99e-7 Lung disease severity in cystic fibrosis; TGCT cis rs6876348 0.520 rs10037758 chr5:128288397 G/A cg25555059 chr5:128301488 SLC27A6 -0.28 -4.76 -0.39 5.24e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6754311 0.731 rs6719488 chr2:136575199 G/T cg07169764 chr2:136633963 MCM6 -0.61 -5.61 -0.45 1.25e-7 Mosquito bite size; TGCT cis rs7582180 0.606 rs10174145 chr2:100932488 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs9486719 1.000 rs12190508 chr6:96898269 T/C cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7208859 0.614 rs216477 chr17:28866744 A/C cg13385521 chr17:29058706 SUZ12P -0.69 -4.56 -0.38 1.19e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg05665937 chr4:1216051 CTBP1 0.25 4.75 0.39 5.64e-6 Obesity-related traits; TGCT cis rs1372520 0.873 rs983361 chr4:90761944 T/G cg14346243 chr4:90757452 SNCA -0.62 -5.42 -0.44 2.92e-7 Neuroticism; TGCT cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg06558623 chr16:89946397 TCF25 0.53 6.59 0.51 1.14e-9 Skin colour saturation; TGCT cis rs9985766 0.958 rs62339878 chr4:150987708 G/T cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs6665290 0.904 rs2297415 chr1:227172903 G/A cg10327440 chr1:227177885 CDC42BPA -1.0 -19.08 -0.86 1.06e-38 Myeloid white cell count; TGCT cis rs514406 0.505 rs405208 chr1:53176674 C/T cg25767906 chr1:53392781 SCP2 -0.47 -5.22 -0.42 7.39e-7 Monocyte count; TGCT cis rs7975161 0.521 rs4630362 chr12:104727744 G/C cg25273343 chr12:104657179 TXNRD1 -0.47 -6.04 -0.48 1.7e-8 Toenail selenium levels; TGCT cis rs3091242 0.933 rs4649084 chr1:25752617 A/G cg23205692 chr1:25664452 TMEM50A 0.5 5.21 0.42 7.8e-7 Erythrocyte sedimentation rate; TGCT cis rs700590 0.723 rs165945 chr5:88110338 A/G cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.24e-7 Educational attainment (years of education); TGCT cis rs8077577 0.895 rs16960986 chr17:18108562 A/G cg09161412 chr17:18057145 MYO15A 0.66 5.4 0.44 3.29e-7 Obesity-related traits; TGCT cis rs42648 0.869 rs6948139 chr7:89937781 T/A cg25739043 chr7:89950458 NA -0.71 -7.18 -0.54 5.5e-11 Homocysteine levels; TGCT cis rs3617 0.591 rs2276823 chr3:52869263 C/A cg11645453 chr3:52864694 ITIH4 -0.29 -5.64 -0.45 1.11e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs28735056 0.875 rs62103176 chr18:77623611 G/C cg05926928 chr17:57297772 GDPD1 0.64 6.76 0.52 4.85e-10 Schizophrenia; TGCT cis rs3733585 0.699 rs11724510 chr4:9958583 C/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.55 -0.51 1.41e-9 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs11175194 0.546 rs73122698 chr12:64210942 C/T cg15233734 chr6:37450823 C6orf129 0.55 6.71 0.52 6.25e-10 Epithelial ovarian cancer; TGCT cis rs72634258 0.517 rs35982383 chr1:7949148 A/G cg26816564 chr1:7831052 VAMP3 0.63 4.55 0.38 1.28e-5 Inflammatory bowel disease; TGCT cis rs4563143 0.675 rs55849754 chr19:29279665 G/A cg12667521 chr19:29218732 NA 0.55 5.9 0.47 3.29e-8 Methadone dose in opioid dependence; TGCT cis rs7819412 0.668 rs4841507 chr8:11046394 C/G cg21775007 chr8:11205619 TDH -0.54 -5.01 -0.41 1.82e-6 Triglycerides; TGCT cis rs4499344 0.633 rs259256 chr19:33151802 C/T cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT cis rs10411936 0.785 rs2363120 chr19:16519871 C/A cg14704714 chr19:15740395 CYP4F8 -0.26 -4.57 -0.38 1.16e-5 White blood cell count;Multiple sclerosis; TGCT cis rs7236492 0.748 rs78531995 chr18:77198370 C/T cg15644404 chr18:77186268 NFATC1 -0.35 -4.76 -0.39 5.22e-6 Inflammatory bowel disease;Crohn's disease; TGCT trans rs629535 0.911 rs627382 chr8:70014081 C/T cg21567404 chr3:27674614 NA -0.59 -9.15 -0.63 1.43e-15 Dupuytren's disease; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs6570726 0.935 rs406343 chr6:145874388 A/G cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4925386 0.840 rs6143024 chr20:60914229 A/G cg24112000 chr20:60950667 NA -0.39 -4.65 -0.39 8.33e-6 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs79724016 1.000 rs1105414 chr1:42144764 C/T cg14093106 chr1:42503579 NA -0.66 -4.96 -0.41 2.29e-6 Breast cancer; TGCT cis rs6964587 1.000 rs60147309 chr7:91736098 C/G cg22709100 chr7:91322751 NA 0.28 4.61 0.38 9.79e-6 Breast cancer; TGCT cis rs4516970 0.826 rs59246098 chr6:160149462 C/CA cg06131755 chr6:160182447 ACAT2 0.61 6.2 0.49 7.52e-9 Iron status biomarkers; TGCT cis rs9457247 0.902 rs34560498 chr6:167395862 A/G cg25258033 chr6:167368657 RNASET2 0.19 4.77 0.39 5.05e-6 Crohn's disease; TGCT cis rs79976124 0.879 rs12213669 chr6:66627704 G/A cg07460842 chr6:66804631 NA 0.58 5.32 0.43 4.77e-7 Type 2 diabetes; TGCT cis rs77861329 1.000 rs164638 chr3:52207886 T/G cg08692210 chr3:52188851 WDR51A 0.93 4.77 0.39 5.04e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs9325144 0.560 rs10785586 chr12:38676197 G/A cg26384229 chr12:38710491 ALG10B -0.66 -5.9 -0.47 3.21e-8 Morning vs. evening chronotype; TGCT cis rs1371867 0.846 rs1788206 chr8:101306966 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg27535305 chr1:53392650 SCP2 0.25 4.95 0.41 2.41e-6 Monocyte count; TGCT cis rs6430585 0.528 rs6711493 chr2:136692553 A/G cg07169764 chr2:136633963 MCM6 1.2 11.66 0.72 1.12e-21 Corneal structure; TGCT cis rs9902453 0.904 rs8071742 chr17:28361669 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs1799949 0.930 rs56729776 chr17:41422131 C/T cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs1555895 0.611 rs3763722 chr10:859270 C/T cg02193355 chr10:851439 NA 0.22 5.24 0.43 6.69e-7 Survival in rectal cancer; TGCT cis rs597539 0.617 rs598353 chr11:68635770 C/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3847687 1.000 rs34853396 chr12:131519265 G/T cg13586425 chr12:131519906 GPR133 -0.35 -5.6 -0.45 1.32e-7 Longevity; TGCT cis rs9549367 0.826 rs9549710 chr13:113898064 A/C cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs9467711 0.606 rs9357006 chr6:26364628 A/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs208520 0.690 rs12208977 chr6:66725257 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.99 10.55 0.69 5.8e-19 Exhaled nitric oxide output; TGCT cis rs7312933 0.501 rs7296357 chr12:42729891 T/G cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.3e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7267979 1.000 rs6050573 chr20:25366065 C/G cg14121845 chr20:25566513 NINL 0.5 5.41 0.44 3.12e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9814567 1.000 rs9289478 chr3:134268619 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -9.2 -0.64 1.11e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs35146811 0.735 rs11767968 chr7:99790971 G/A cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs9295536 0.651 rs6900792 chr6:22136938 T/C cg25792714 chr6:21666554 FLJ22536 -0.52 -4.73 -0.39 6.03e-6 Neuroblastoma; TGCT cis rs11190604 1.000 rs3750633 chr10:102308214 C/T cg16342193 chr10:102329863 NA -0.41 -5.13 -0.42 1.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs16957091 0.647 rs28581361 chr15:43396604 C/T cg17935677 chr15:44119062 WDR76 0.53 4.58 0.38 1.11e-5 MGMT methylation in smokers; TGCT cis rs6714710 0.580 rs11680018 chr2:98479581 C/A cg26665480 chr2:98280029 ACTR1B 0.64 6.09 0.48 1.29e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs12477438 0.765 rs7571390 chr2:99626593 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.72 -7.12 -0.54 7.76e-11 Chronic sinus infection; TGCT cis rs7552404 1.000 rs7533888 chr1:76160449 A/C cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3096299 0.582 rs12935119 chr16:89542874 A/T cg06640241 chr16:89574553 SPG7 0.59 5.69 0.45 8.77e-8 Multiple myeloma (IgH translocation); TGCT cis rs6964587 1.000 rs28410528 chr7:91647390 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs67311347 1.000 rs7612015 chr3:40399974 A/C cg13683864 chr3:40499215 RPL14 -1.02 -10.8 -0.7 1.43e-19 Renal cell carcinoma; TGCT cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg24531977 chr5:56204891 C5orf35 -0.94 -9.1 -0.63 1.9e-15 Initial pursuit acceleration; TGCT cis rs7267979 1.000 rs1046073 chr20:25281333 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9394169 0.875 rs1547670 chr6:33775868 G/A cg00334056 chr6:33755658 LEMD2 -0.24 -4.55 -0.38 1.28e-5 Essential tremor; TGCT cis rs11190604 1.000 rs10883502 chr10:102238343 T/G cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12188164 0.931 rs115554641 chr5:443236 C/G cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs9359856 0.623 rs1179906 chr6:90323624 T/C cg13799429 chr6:90582589 CASP8AP2 -0.43 -4.69 -0.39 7.15e-6 Bipolar disorder; TGCT trans rs10022799 1.000 rs6850485 chr4:168150023 T/C cg08507725 chr4:8239220 SH3TC1 0.3 6.66 0.51 8e-10 Cognitive function; TGCT cis rs9818758 0.556 rs9880309 chr3:49304329 G/C cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs17741873 0.722 rs10824045 chr10:75656543 A/G cg07699608 chr10:75541558 CHCHD1 0.6 4.72 0.39 6.35e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs4822044 0.617 rs13054514 chr22:42130383 A/G cg06634786 chr22:41940651 POLR3H 0.79 7.29 0.55 3.13e-11 Cannabis dependence symptom count; TGCT cis rs12220898 0.526 rs4838505 chr10:50556797 T/C cg07746882 chr10:49866792 NA 0.32 4.47 0.37 1.77e-5 Inflammatory biomarkers; TGCT cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg02187348 chr16:89574699 SPG7 0.62 6.7 0.52 6.56e-10 Multiple myeloma (IgH translocation); TGCT cis rs2637266 1.000 rs12783273 chr10:78353221 T/C cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT trans rs10435719 0.902 rs7006538 chr8:11804982 A/G cg15556689 chr8:8085844 FLJ10661 0.76 7.28 0.55 3.36e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT trans rs1005277 0.579 rs2103938 chr10:38493998 T/G cg17830980 chr10:43048298 ZNF37B -0.82 -10.2 -0.68 4.02e-18 Extrinsic epigenetic age acceleration; TGCT cis rs4699052 0.625 rs2138592 chr4:104255718 A/G cg16532752 chr4:104119610 CENPE -0.51 -5.01 -0.41 1.8e-6 Testicular germ cell tumor; TGCT cis rs9325144 0.554 rs1906264 chr12:38739490 A/G cg26384229 chr12:38710491 ALG10B 0.61 5.62 0.45 1.22e-7 Morning vs. evening chronotype; TGCT cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg03806693 chr22:41940476 POLR3H 1.13 12.99 0.76 6.98e-25 Vitiligo; TGCT cis rs10791097 0.739 rs12279359 chr11:130730544 G/A cg05962950 chr11:130786565 SNX19 0.8 9.66 0.66 8.34e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs16866061 1.000 rs3768886 chr2:225450161 G/C cg12698349 chr2:225449008 CUL3 1.02 9.8 0.66 3.83e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg02725872 chr8:58115012 NA -0.39 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs9858542 0.953 rs35115732 chr3:49475155 T/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2013441 1.000 rs9325894 chr17:20197101 T/C cg23224458 chr17:20280056 CCDC144C -0.42 -4.91 -0.4 2.82e-6 Obesity-related traits; TGCT cis rs763121 0.853 rs6519124 chr22:39045099 T/C cg06022373 chr22:39101656 GTPBP1 0.8 8.25 0.6 1.95e-13 Menopause (age at onset); TGCT cis rs4803468 1.000 rs3213861 chr19:41919944 A/C cg09537434 chr19:41945824 ATP5SL -0.9 -10.59 -0.69 4.65e-19 Height; TGCT cis rs16958440 0.867 rs61689863 chr18:44669157 A/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.76 0.46 6.35e-8 Height; TGCT cis rs67311347 1.000 rs73078163 chr3:40479958 C/T cg13683864 chr3:40499215 RPL14 -1.18 -12.96 -0.76 8.39e-25 Renal cell carcinoma; TGCT cis rs9911578 1.000 rs12940681 chr17:56933622 T/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.25 -0.49 6.03e-9 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs9393708 chr6:26362643 C/T cg16898833 chr6:26189333 HIST1H4D -1.09 -5.35 -0.43 4.15e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs174601 0.861 rs174550 chr11:61571478 T/C cg01500311 chr11:61656094 FADS3 -0.3 -5.25 -0.43 6.42e-7 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg13607699 chr17:42295918 UBTF -0.59 -5.39 -0.44 3.37e-7 Total body bone mineral density; TGCT cis rs11642862 1.000 rs11642862 chr16:30785824 A/G cg02466173 chr16:30829666 NA 0.36 4.68 0.39 7.31e-6 Tonsillectomy; TGCT cis rs9467773 1.000 rs9393732 chr6:26530898 G/A cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9291683 0.546 rs6820188 chr4:10051655 C/T cg00071950 chr4:10020882 SLC2A9 0.55 6.22 0.49 6.92e-9 Bone mineral density; TGCT cis rs1971762 0.545 rs6580949 chr12:53924293 T/C cg16917193 chr12:54089295 NA 1.01 10.33 0.68 1.96e-18 Height; TGCT trans rs9388451 0.839 rs1811852 chr6:126071575 G/C cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.29 -0.6 1.61e-13 Brugada syndrome; TGCT cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg21724239 chr8:58056113 NA 0.39 5.24 0.43 6.73e-7 Developmental language disorder (linguistic errors); TGCT cis rs806215 0.526 rs3808078 chr7:127581677 G/A cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.37e-6 Type 2 diabetes; TGCT cis rs2075371 1.000 rs432487 chr7:133990114 T/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs881375 0.715 rs10760119 chr9:123646060 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.79e-7 Rheumatoid arthritis; TGCT trans rs8073060 0.586 rs7214250 chr17:33981704 C/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs854765 0.547 rs2955356 chr17:17964717 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.8 -8.45 -0.6 6.61e-14 Total body bone mineral density; TGCT trans rs561341 0.739 rs8070554 chr17:30216868 A/T cg20587970 chr11:113659929 NA 0.65 8.95 0.63 4.33e-15 Hip circumference adjusted for BMI; TGCT cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 6.06 0.48 1.54e-8 Alzheimer's disease; TGCT cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs554111 0.560 rs592060 chr1:21050958 A/G cg08890418 chr1:21044141 KIF17 -0.77 -7.47 -0.56 1.27e-11 Facial morphology (factor 17, height of vermillion upper lip); TGCT trans rs459571 0.959 rs2520100 chr9:136918137 A/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.77 -8.29 -0.6 1.58e-13 Platelet distribution width; TGCT cis rs362272 0.524 rs6819202 chr4:3368264 G/A cg22655196 chr4:3374909 RGS12 0.23 4.76 0.39 5.27e-6 Serum sulfate level; TGCT cis rs9535307 0.615 rs3736830 chr13:50306221 G/C cg08779649 chr13:50194554 NA 0.41 4.81 0.4 4.35e-6 Obesity-related traits; TGCT cis rs9291683 0.609 rs4622999 chr4:10003395 C/G cg11266682 chr4:10021025 SLC2A9 0.67 9.42 0.65 3.21e-16 Bone mineral density; TGCT cis rs68092024 0.704 rs793487 chr3:99495422 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.53 6.33 0.49 4.06e-9 Cleft lip with or without cleft palate; TGCT cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs10197940 0.545 rs2444267 chr2:152308611 T/G cg06191203 chr2:152266755 RIF1 -0.57 -4.83 -0.4 4.02e-6 Lung cancer; TGCT cis rs1048238 0.935 rs761760 chr1:16342419 A/G cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Systolic blood pressure; TGCT cis rs910316 1.000 rs175442 chr14:75603564 T/C cg11812906 chr14:75593930 NEK9 -0.73 -7.13 -0.54 7.35e-11 Height; TGCT cis rs4455778 0.561 rs6975663 chr7:49122743 G/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7216064 1.000 rs7223930 chr17:65842186 G/A cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6490294 0.851 rs56814171 chr12:112402950 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs2019216 0.500 rs7210996 chr17:21917331 G/A cg22648282 chr17:21454238 C17orf51 -0.6 -5.54 -0.45 1.75e-7 Pelvic organ prolapse; TGCT cis rs10791097 1.000 rs10791098 chr11:130718711 T/G cg05962950 chr11:130786565 SNX19 0.75 8.14 0.59 3.64e-13 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1135314 0.580 rs10870116 chr9:139287674 G/A cg13741927 chr9:139327495 INPP5E -0.23 -4.68 -0.39 7.24e-6 Acute insulin response; TGCT cis rs7647973 0.626 rs12715437 chr3:49751856 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs4819052 0.851 rs1006779 chr21:46670752 A/G cg06618935 chr21:46677482 NA -0.32 -4.9 -0.4 2.95e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs950776 0.714 rs3743073 chr15:78909539 G/T cg06917634 chr15:78832804 PSMA4 -0.62 -4.95 -0.41 2.39e-6 Sudden cardiac arrest; TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg26354017 chr1:205819088 PM20D1 0.68 9.58 0.65 1.31e-16 Menarche (age at onset); TGCT cis rs66716358 0.800 rs10838255 chr11:44320172 C/T cg02785814 chr11:44338707 NA -0.47 -4.53 -0.38 1.35e-5 Monobrow; TGCT cis rs10504229 0.683 rs7817188 chr8:58129549 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9534288 0.912 rs9534297 chr13:46624630 T/C cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs6752107 0.936 rs10187822 chr2:234206474 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.71 0.39 6.47e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg07154950 chr22:24370586 NA -0.21 -4.55 -0.38 1.27e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs889312 0.500 rs832570 chr5:56156408 G/A cg12311346 chr5:56204834 C5orf35 -0.48 -5.26 -0.43 6.05e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs4727027 0.933 rs1468369 chr7:148839840 G/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs11955175 1.000 rs77394428 chr5:40743517 A/G cg17351974 chr5:40835760 RPL37 0.84 5.34 0.43 4.23e-7 Bipolar disorder and schizophrenia; TGCT trans rs1814175 0.565 rs4881721 chr11:49761851 G/A cg03929089 chr4:120376271 NA -0.57 -6.61 -0.51 1e-9 Height; TGCT cis rs7267979 0.933 rs6138571 chr20:25435388 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3617 0.598 rs56214994 chr3:52878600 G/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1448094 0.717 rs60713909 chr12:86294469 C/G cg02569458 chr12:86230093 RASSF9 0.36 4.71 0.39 6.44e-6 Major depressive disorder; TGCT cis rs7726839 0.574 rs72707007 chr5:661856 T/C cg16624210 chr5:671434 TPPP 0.41 4.74 0.39 5.82e-6 Obesity-related traits; TGCT cis rs1163251 0.837 rs611365 chr1:120242571 C/T cg19096424 chr1:120255104 PHGDH 0.6 5.94 0.47 2.66e-8 Blood metabolite levels; TGCT cis rs10504229 0.679 rs72649131 chr8:58054288 G/T cg08280861 chr8:58055591 NA 0.35 4.88 0.4 3.2e-6 Developmental language disorder (linguistic errors); TGCT cis rs6088590 1.000 rs11698977 chr20:33449691 C/T cg24642439 chr20:33292090 TP53INP2 0.73 6.41 0.5 2.7e-9 Coronary artery disease; TGCT cis rs7208859 0.573 rs73267829 chr17:29003939 G/A cg13385521 chr17:29058706 SUZ12P 0.77 4.61 0.38 9.67e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.45 0.56 1.42e-11 Prudent dietary pattern; TGCT cis rs9527 0.830 rs3740392 chr10:104636855 T/C cg04362960 chr10:104952993 NT5C2 0.66 5.27 0.43 5.93e-7 Arsenic metabolism; TGCT cis rs2032447 0.610 rs189911 chr6:25965942 A/G cg03264133 chr6:25882463 NA -0.66 -5.96 -0.47 2.4e-8 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.767 rs10763787 chr10:30700753 G/A cg13289132 chr10:30722225 MAP3K8 0.44 5.46 0.44 2.49e-7 Inflammatory bowel disease; TGCT cis rs4494114 0.967 rs3748563 chr1:39311998 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.43 -0.5 2.52e-9 Blood protein levels; TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg01802117 chr1:53393560 SCP2 -0.39 -4.55 -0.38 1.27e-5 Monocyte count; TGCT cis rs2073300 0.793 rs36165478 chr20:23457261 C/T cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs1799949 0.965 rs8176310 chr17:41199913 T/C cg10047753 chr17:41438598 NA 0.68 6.16 0.48 9.22e-9 Menopause (age at onset); TGCT cis rs7666738 0.830 rs35213297 chr4:98984049 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28735056 0.933 rs499472 chr18:77589759 C/T cg20368463 chr18:77673604 PQLC1 -0.45 -5.53 -0.44 1.84e-7 Schizophrenia; TGCT cis rs854765 0.547 rs2955372 chr17:17970229 T/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.69 -0.39 7e-6 Total body bone mineral density; TGCT cis rs617219 0.698 rs10055956 chr5:78479678 G/A cg23514016 chr5:78407564 BHMT 0.35 5.53 0.44 1.82e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs422249 0.819 rs174605 chr11:61626921 G/T cg01500311 chr11:61656094 FADS3 -0.3 -5.12 -0.42 1.11e-6 Trans fatty acid levels; TGCT cis rs12142240 0.698 rs12385697 chr1:46818898 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs13088645 0.532 rs9835166 chr3:134166224 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.69 6.29 0.49 4.88e-9 Coronary artery disease; TGCT cis rs7582180 0.663 rs1114595 chr2:100960072 T/A cg08017756 chr2:100939284 LONRF2 -0.3 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.576 rs246074 chr5:140307969 C/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.09e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs9399135 0.935 rs11759999 chr6:135370495 G/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.28e-6 Red blood cell count; TGCT cis rs7772486 0.686 rs9497395 chr6:146013592 A/G cg23711669 chr6:146136114 FBXO30 -0.84 -9.19 -0.64 1.15e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 1.000 rs7659718 chr4:17638020 A/C cg16339924 chr4:17578868 LAP3 0.71 5.75 0.46 6.46e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12142240 0.698 rs1057535 chr1:46815898 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs250677 0.652 rs168751 chr5:148438264 C/T cg23229984 chr5:148520753 ABLIM3 0.22 4.98 0.41 2.05e-6 Breast cancer; TGCT cis rs992157 0.767 rs2382822 chr2:219173327 T/C cg00012203 chr2:219082015 ARPC2 -0.82 -8.13 -0.59 3.76e-13 Colorectal cancer; TGCT cis rs4975709 0.838 rs4975752 chr5:1880588 A/C cg14773178 chr5:1868261 NA 0.33 4.87 0.4 3.31e-6 Cardiovascular disease risk factors; TGCT cis rs2224391 1.000 rs2753248 chr6:5262154 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -6.05 -0.48 1.61e-8 Height; TGCT cis rs12477438 0.798 rs2123686 chr2:99690135 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg20607798 chr8:58055168 NA 0.49 4.63 0.38 9.07e-6 Developmental language disorder (linguistic errors); TGCT cis rs10823500 0.674 rs7089860 chr10:71992848 C/G cg04118878 chr10:71993077 PPA1 0.58 5.31 0.43 4.9e-7 Blood protein levels; TGCT cis rs3008870 1.000 rs1925411 chr1:67370292 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.84 0.73 4.25e-22 Lymphocyte percentage of white cells; TGCT cis rs826838 0.967 rs11169169 chr12:39093153 A/C cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3.1e-10 Heart rate; TGCT cis rs1799949 0.965 rs799917 chr17:41244936 G/A cg05368731 chr17:41323189 NBR1 1.01 11.17 0.71 1.78e-20 Menopause (age at onset); TGCT cis rs7246657 0.943 rs1559229 chr19:37876197 T/C cg18154014 chr19:37997991 ZNF793 0.74 5.33 0.43 4.48e-7 Coronary artery calcification; TGCT cis rs3087591 0.659 rs757376 chr17:29717909 A/G cg24425628 chr17:29625626 OMG;NF1 0.4 5.87 0.47 3.67e-8 Hip circumference; TGCT cis rs2013441 1.000 rs11654025 chr17:20198160 A/T cg23224458 chr17:20280056 CCDC144C -0.37 -4.6 -0.38 1.05e-5 Obesity-related traits; TGCT cis rs11586313 1.000 rs11586313 chr1:152890470 C/T cg07796016 chr1:152779584 LCE1C -0.51 -5.97 -0.47 2.3e-8 Vitamin D levels; TGCT cis rs9372253 0.934 rs9320327 chr6:110715194 T/A cg00083206 chr6:110721305 DDO -0.43 -6.44 -0.5 2.33e-9 Platelet distribution width; TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg24503407 chr1:205819492 PM20D1 0.6 8.53 0.61 4.21e-14 Menarche (age at onset); TGCT cis rs4808199 0.894 rs9304960 chr19:19465529 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.63 4.56 0.38 1.23e-5 Nonalcoholic fatty liver disease; TGCT cis rs6671200 0.541 rs3738170 chr1:95699604 G/C cg03123541 chr1:95699097 RWDD3 -0.8 -7.03 -0.53 1.24e-10 Stearic acid (18:0) levels; TGCT cis rs1215050 0.740 rs6854802 chr4:99065480 A/C cg05340658 chr4:99064831 C4orf37 0.44 5.3 0.43 5.03e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1165205 0.500 rs629835 chr6:25879330 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.53 4.55 0.38 1.26e-5 Urate levels; TGCT cis rs9894429 0.682 rs7406360 chr17:79591545 G/A cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.22e-10 Eye color traits; TGCT cis rs9733 0.596 rs6690725 chr1:150632322 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs8067545 0.603 rs10083830 chr17:19965883 G/A cg18979559 chr17:20280153 CCDC144C 0.45 4.69 0.39 7.15e-6 Schizophrenia; TGCT cis rs3008870 1.000 rs2755246 chr1:67488984 A/G cg03991309 chr1:68237761 GNG12 0.27 4.46 0.37 1.81e-5 Lymphocyte percentage of white cells; TGCT cis rs6570726 0.846 rs7762536 chr6:145923145 T/C cg23711669 chr6:146136114 FBXO30 0.84 8.91 0.62 5.38e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs939658 0.728 rs11637459 chr15:79413554 A/G cg17916960 chr15:79447300 NA -0.46 -6.39 -0.5 3.11e-9 Refractive error; TGCT cis rs7772486 0.875 rs12194437 chr6:146411440 A/G cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1372520 0.684 rs356191 chr4:90688120 G/A cg14346243 chr4:90757452 SNCA 0.62 5.29 0.43 5.26e-7 Neuroticism; TGCT cis rs9291683 0.588 rs2240722 chr4:10020757 A/G cg00071950 chr4:10020882 SLC2A9 0.72 9.86 0.66 2.78e-17 Bone mineral density; TGCT cis rs17076896 0.786 rs61956076 chr13:19932216 A/G cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7095607 1.000 rs10998009 chr10:69953416 A/G cg18986048 chr10:69913749 MYPN 0.46 5.08 0.41 1.37e-6 Lung function (FVC); TGCT cis rs854765 0.663 rs3183702 chr17:17747289 A/G cg04398451 chr17:18023971 MYO15A 0.31 4.65 0.39 8.49e-6 Total body bone mineral density; TGCT trans rs1814175 0.538 rs1684260 chr11:49224231 G/A cg15704280 chr7:45808275 SEPT13 0.71 7.66 0.57 4.55e-12 Height; TGCT cis rs6569992 0.636 rs7757054 chr6:135487614 C/T cg22676075 chr6:135203613 NA -0.74 -5.03 -0.41 1.69e-6 Red blood cell traits; TGCT cis rs735396 1.000 rs1169310 chr12:121439433 G/A cg02403541 chr12:121454288 C12orf43 0.66 6.27 0.49 5.35e-9 N-glycan levels; TGCT cis rs17376456 1.000 rs6867042 chr5:93555761 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 7.92e-6 Diabetic retinopathy; TGCT cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs6684514 1.000 rs12022194 chr1:156312331 T/A cg16558208 chr1:156270281 VHLL 0.48 9.61 0.65 1.13e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.47 -0.37 1.72e-5 Bipolar disorder; TGCT cis rs4936891 0.563 rs78294880 chr11:123890006 C/T cg22125253 chr11:123886957 OR10G4 0.21 4.74 0.39 5.66e-6 Male fertility; TGCT cis rs7833790 0.724 rs12676336 chr8:82771008 C/T cg17211192 chr8:82754475 SNX16 0.97 9.09 0.63 2.04e-15 Diastolic blood pressure; TGCT cis rs2066819 0.892 rs77415512 chr12:56627300 A/G cg26714650 chr12:56694279 CS -1.42 -5.7 -0.46 8.43e-8 Psoriasis vulgaris; TGCT cis rs9303401 0.659 rs12952325 chr17:56899371 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.11 0.48 1.17e-8 Cognitive test performance; TGCT cis rs4595586 0.545 rs12823487 chr12:39391286 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs9810089 0.843 rs838202 chr3:136035217 G/A cg12473912 chr3:136751656 NA 0.35 4.96 0.41 2.28e-6 Gestational age at birth (child effect); TGCT cis rs9929218 0.529 rs11075694 chr16:68730366 C/T cg01251360 chr16:68772225 CDH1 -0.25 -4.67 -0.39 7.62e-6 Colorectal cancer; TGCT cis rs910187 0.605 rs62201430 chr20:45808227 A/T cg27589058 chr20:45804311 EYA2 -0.4 -9.0 -0.63 3.33e-15 Migraine; TGCT cis rs2180341 0.960 rs9401953 chr6:127687574 G/A cg27446573 chr6:127587934 RNF146 1.1 10.61 0.69 4.22e-19 Breast cancer; TGCT cis rs2562456 0.917 rs2681392 chr19:21695987 T/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs2033711 0.837 rs3764535 chr19:58929052 G/A cg12042659 chr19:58951599 ZNF132 0.51 4.6 0.38 1.05e-5 Uric acid clearance; TGCT cis rs4819052 0.851 rs914218 chr21:46698445 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.716 rs1426660 chr4:98876792 T/A cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7698623 0.541 rs7682273 chr4:88781772 C/T cg02735620 chr4:88950514 PKD2 -0.45 -4.79 -0.39 4.73e-6 Cardiovascular disease risk factors; TGCT cis rs4862307 0.836 rs4507404 chr4:185003767 C/T cg06737308 chr4:185021514 ENPP6 -0.35 -5.03 -0.41 1.65e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT trans rs8073060 0.963 rs35614987 chr17:33869466 A/C cg19694781 chr19:47549865 TMEM160 0.42 7.72 0.57 3.37e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs35883536 0.647 rs10875312 chr1:101042320 G/C cg14855972 chr1:101004472 GPR88 -0.24 -4.49 -0.37 1.64e-5 Monocyte count; TGCT cis rs9818758 0.607 rs9837237 chr3:49215583 G/T cg00383909 chr3:49044727 WDR6 1.29 6.62 0.51 9.88e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg11644478 chr21:40555479 PSMG1 1.01 10.47 0.69 8.99e-19 Cognitive function; TGCT cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs4242434 0.927 rs34027561 chr8:22465385 T/C cg21658235 chr8:22456391 C8orf58 0.43 4.53 0.38 1.36e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg15242686 chr22:24348715 GSTTP1 -0.46 -5.24 -0.43 6.6e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs968451 0.789 rs5757603 chr22:39677128 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.76 7.44 0.56 1.47e-11 Primary biliary cholangitis; TGCT cis rs6500602 0.702 rs2304634 chr16:4500544 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.26 4.84 0.4 3.83e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs7678557 chr4:99057329 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10746514 1.000 rs12129814 chr1:232251730 C/A cg09506761 chr1:232265262 NA 0.53 5.31 0.43 4.79e-7 Response to statin therapy; TGCT cis rs2456568 0.900 rs2000960 chr11:93682348 C/T cg26875233 chr11:93583750 C11orf90 -0.45 -5.65 -0.45 1.04e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836950 0.565 rs2836945 chr21:40596757 C/T cg17971929 chr21:40555470 PSMG1 -0.51 -4.64 -0.38 8.88e-6 Menarche (age at onset); TGCT cis rs3784262 0.669 rs4646555 chr15:58355345 G/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6540559 0.546 rs57315825 chr1:210030197 C/T cg23283495 chr1:209979779 IRF6 0.71 5.51 0.44 2.01e-7 Cleft lip with or without cleft palate; TGCT cis rs9811920 0.609 rs2452320 chr3:99645216 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.59 -6.77 -0.52 4.51e-10 Axial length; TGCT cis rs4891159 0.548 rs690082 chr18:74116668 C/T cg24786174 chr18:74118243 ZNF516 0.71 15.66 0.82 3.6e-31 Longevity; TGCT cis rs1008375 1.000 rs1008375 chr4:17682834 T/C cg18681998 chr4:17616180 MED28 0.89 10.41 0.68 1.25e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs208520 0.690 rs12201156 chr6:66720874 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs9527 0.615 rs2152915 chr10:104691732 A/T cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs1843834 0.721 rs1601730 chr2:225590153 G/A cg22455342 chr2:225449267 CUL3 0.69 6.58 0.51 1.2e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs3026101 0.624 rs17635627 chr17:5296059 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.53 0.38 1.38e-5 Body mass index; TGCT cis rs17376456 0.825 rs10064368 chr5:93266396 C/A cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs6121246 0.738 rs6121242 chr20:30410877 T/C cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs17764205 0.777 rs113305163 chr19:3252194 G/C cg18738857 chr19:3606974 TBXA2R -0.73 -4.53 -0.38 1.35e-5 Bipolar disorder and schizophrenia; TGCT cis rs6121246 0.529 rs6060359 chr20:30209740 A/G cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs40363 0.723 rs2736 chr16:3536872 G/A cg22508957 chr16:3507546 NAT15 -0.51 -4.54 -0.38 1.29e-5 Tuberculosis; TGCT cis rs6952808 0.723 rs4721264 chr7:2012997 G/A cg22963979 chr7:1858916 MAD1L1 -0.43 -6.77 -0.52 4.65e-10 Bipolar disorder and schizophrenia; TGCT cis rs9818758 0.607 rs9990153 chr3:49291883 C/T cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs208520 1.000 rs28773210 chr6:66993566 C/T cg07460842 chr6:66804631 NA 0.79 6.85 0.52 3.05e-10 Exhaled nitric oxide output; TGCT cis rs10504229 0.645 rs6995814 chr8:58114159 C/T cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs2288884 1.000 rs76368799 chr19:52561507 A/G cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs9818758 0.607 rs11706052 chr3:49064110 A/G cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7666738 0.830 rs35433756 chr4:99070555 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs116095464 0.558 rs9687621 chr5:229194 C/T cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.73e-10 Breast cancer; TGCT cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.82e-10 Electroencephalogram traits; TGCT cis rs10908458 0.743 rs7367207 chr1:155079477 C/T cg23973274 chr1:155060172 NA -0.25 -4.51 -0.38 1.51e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3743266 0.507 rs3759910 chr15:60768469 C/T cg18480781 chr15:60294291 NA 0.7 5.28 0.43 5.65e-7 Menarche (age at onset); TGCT cis rs12780845 0.558 rs7090965 chr10:17216803 A/G cg01003015 chr10:17271136 VIM 0.56 4.87 0.4 3.36e-6 Homocysteine levels; TGCT cis rs4372836 0.729 rs11684695 chr2:29088450 G/T cg09522027 chr2:28974177 PPP1CB 0.67 7.01 0.53 1.38e-10 Body mass index; TGCT cis rs476633 0.691 rs2164996 chr15:41536624 A/G cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.07 -0.54 1.01e-10 Glomerular filtration rate (creatinine); TGCT cis rs9467773 1.000 rs1078679 chr6:26568741 C/T cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.525 rs1535274 chr6:26520747 A/C cg15659132 chr6:26577336 NA 0.73 9.04 0.63 2.64e-15 Intelligence (multi-trait analysis); TGCT cis rs6674176 0.542 rs803679 chr1:44349405 G/A cg12908607 chr1:44402522 ARTN -0.7 -7.96 -0.58 9.2e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs10791097 0.667 rs1893019 chr11:130756664 C/G cg05962950 chr11:130786565 SNX19 0.9 11.06 0.7 3.32e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs9906944 0.707 rs3816272 chr17:47120467 A/G cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs11690935 0.877 rs13024846 chr2:172835803 C/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -11.94 -0.73 2.37e-22 Schizophrenia; TGCT cis rs769267 1.000 rs8103197 chr19:19443466 C/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg07092213 chr7:1199455 ZFAND2A -0.43 -4.66 -0.39 8.09e-6 Longevity;Endometriosis; TGCT cis rs9952991 0.941 rs9952749 chr18:12780456 A/G cg23598886 chr18:12777645 NA 0.62 5.78 0.46 5.63e-8 Inflammatory skin disease; TGCT cis rs1997103 0.871 rs1997101 chr7:55399652 A/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7635838 0.684 rs384989 chr3:11320120 C/T cg00170343 chr3:11313890 ATG7 0.63 6.22 0.49 7.07e-9 HDL cholesterol; TGCT cis rs7914558 0.966 rs12571568 chr10:104891396 C/G cg15744005 chr10:104629667 AS3MT -0.42 -5.24 -0.43 6.69e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2762353 0.574 rs4409177 chr6:25694491 T/G cg03517284 chr6:25882590 NA 0.92 9.18 0.64 1.19e-15 Blood metabolite levels; TGCT cis rs4713118 0.586 rs6905516 chr6:28086478 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Parkinson's disease; TGCT cis rs3749237 0.537 rs4459909 chr3:49469217 T/C cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs875971 0.862 rs778736 chr7:65813848 C/T cg11764359 chr7:65958608 NA 0.55 4.99 0.41 1.98e-6 Aortic root size; TGCT cis rs11748684 0.524 rs13162596 chr5:42576257 A/G cg01169772 chr5:41904236 C5orf51 -0.93 -4.52 -0.38 1.41e-5 Response to taxane treatment (docetaxel); TGCT cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg16049864 chr8:95962084 TP53INP1 -0.72 -10.17 -0.67 4.8e-18 Type 2 diabetes; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg25703541 chr22:24373054 LOC391322 -0.8 -6.48 -0.5 1.97e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7552404 1.000 rs1498312 chr1:76177849 C/T cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs7618501 0.902 rs7645061 chr3:49868842 C/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs1008375 1.000 rs10939746 chr4:17684951 A/G cg16339924 chr4:17578868 LAP3 -0.55 -4.52 -0.38 1.42e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs713587 0.691 rs754537 chr2:25176277 A/T cg01884057 chr2:25150051 NA -0.31 -5.93 -0.47 2.79e-8 Body mass index in non-asthmatics; TGCT cis rs2243480 1.000 rs160652 chr7:65538431 A/G cg07424592 chr7:64974309 NA 1.33 8.82 0.62 8.94e-15 Diabetic kidney disease; TGCT trans rs17684571 0.872 rs13191164 chr6:56566630 G/A cg14229071 chr15:89282588 NA 0.51 6.68 0.51 7.14e-10 Schizophrenia; TGCT cis rs7582180 0.715 rs7571306 chr2:100906084 G/C cg08017756 chr2:100939284 LONRF2 -0.28 -4.76 -0.39 5.37e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg08859206 chr1:53392774 SCP2 -0.48 -7.58 -0.56 7.09e-12 Monocyte count; TGCT cis rs7584330 0.910 rs7606177 chr2:238394913 G/C cg16989719 chr2:238392110 NA -0.27 -4.72 -0.39 6.24e-6 Prostate cancer; TGCT cis rs7760949 0.889 rs9382688 chr6:13926746 A/T cg27413430 chr6:13925136 RNF182 0.73 6.79 0.52 4.22e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2153535 0.580 rs1034273 chr6:8468145 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs4988958 0.527 rs6756161 chr2:103048417 C/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs860554 0.640 rs2300293 chr1:201264902 C/T cg01022117 chr1:201258280 PKP1 -0.35 -6.96 -0.53 1.77e-10 Panic disorder; TGCT cis rs116095464 0.558 rs9687898 chr5:253952 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs10791097 0.694 rs2155750 chr11:130751261 A/C cg12179176 chr11:130786555 SNX19 0.82 10.15 0.67 5.45e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1372520 0.684 rs2572318 chr4:90718719 C/T cg01966878 chr4:90757139 SNCA -0.33 -4.52 -0.38 1.42e-5 Neuroticism; TGCT cis rs2549003 1.000 rs2070731 chr5:131819798 T/C cg00255919 chr5:131827918 IRF1 0.19 4.61 0.38 9.78e-6 Asthma (sex interaction); TGCT cis rs3806843 0.576 rs246043 chr5:140330924 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs3733631 0.948 rs28438896 chr4:104625753 C/T cg24090629 chr4:104641072 TACR3 -0.73 -5.81 -0.46 4.96e-8 Menarche (age at onset); TGCT cis rs4819052 1.000 rs4818769 chr21:46667451 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.91 7.51 0.56 9.9e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3008870 0.583 rs2147838 chr1:67399466 T/C cg11518657 chr1:67396239 MIER1 0.6 4.78 0.39 4.79e-6 Lymphocyte percentage of white cells; TGCT cis rs12142240 0.698 rs67487250 chr1:46811333 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs597539 0.652 rs660614 chr11:68659488 G/A cg06028808 chr11:68637592 NA 0.51 6.56 0.51 1.32e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13202913 0.943 rs9383572 chr6:151795210 C/A cg03627880 chr6:151815985 C6orf97 -0.7 -5.02 -0.41 1.75e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs11190604 1.000 rs10883513 chr10:102316964 A/G cg16342193 chr10:102329863 NA -0.44 -5.38 -0.44 3.52e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.927 rs11736876 chr4:98987206 A/G cg17366294 chr4:99064904 C4orf37 0.77 7.0 0.53 1.4e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11690462 0.963 rs17529423 chr2:26583506 A/C cg04726446 chr2:26624865 C2orf39 0.42 4.63 0.38 9.08e-6 Coronary artery disease; TGCT cis rs1865760 0.865 rs9467650 chr6:25958235 A/G cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs789859 0.794 rs1037929 chr3:194375000 G/A cg21106136 chr3:194405973 FAM43A -0.39 -5.15 -0.42 9.92e-7 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs1497406 0.744 rs6656611 chr1:16515805 T/C cg20430773 chr1:16534157 ARHGEF19 0.52 6.25 0.49 6.18e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4253772 0.550 rs6007779 chr22:46678615 A/C cg24881330 chr22:46731750 TRMU 0.88 5.3 0.43 5.07e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs433598 0.704 rs163267 chr16:20660957 T/A cg16616769 chr16:19727142 IQCK;C16orf88 -0.21 -4.6 -0.38 1.01e-5 Schizophrenia; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg13695892 chr22:41940480 POLR3H -0.95 -8.65 -0.61 2.21e-14 Vitiligo; TGCT trans rs783396 0.901 rs1676010 chr6:106999658 A/T cg09013229 chr1:225332226 DNAH14 -0.58 -6.83 -0.52 3.35e-10 Stroke; TGCT cis rs10972341 1.000 rs10972342 chr9:35144722 T/C cg00812861 chr9:35114699 KIAA1539 0.33 5.0 0.41 1.88e-6 Weight; TGCT cis rs4073582 0.516 rs1151539 chr11:66031660 C/T cg16950941 chr11:66035639 RAB1B 0.58 5.44 0.44 2.67e-7 Gout; TGCT cis rs7833790 0.660 rs67666182 chr8:82772037 A/G cg17211192 chr8:82754475 SNX16 0.97 9.09 0.63 2.04e-15 Diastolic blood pressure; TGCT cis rs9902453 0.933 rs7216487 chr17:28502642 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs13326165 0.760 rs11714402 chr3:52391735 G/T cg27565382 chr3:53032988 SFMBT1 -0.33 -4.66 -0.39 8.03e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7833790 0.660 rs7839178 chr8:82763479 A/G cg06027949 chr8:82754900 SNX16 0.67 5.14 0.42 1.06e-6 Diastolic blood pressure; TGCT cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg21724239 chr8:58056113 NA 0.47 4.99 0.41 1.96e-6 Developmental language disorder (linguistic errors); TGCT cis rs7547997 0.685 rs12029228 chr1:158346963 C/T cg07950803 chr1:158223934 CD1A 0.31 4.6 0.38 1.01e-5 QRS duration; TGCT cis rs4689388 0.824 rs6446482 chr4:6295693 C/G cg14416269 chr4:6271139 WFS1 0.4 5.24 0.43 6.66e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6121246 0.697 rs6120970 chr20:30232452 C/T cg13852791 chr20:30311386 BCL2L1 0.74 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin; TGCT cis rs713587 0.520 rs487617 chr2:25309756 C/G cg01884057 chr2:25150051 NA -0.26 -4.87 -0.4 3.36e-6 Body mass index in non-asthmatics; TGCT cis rs35306767 0.714 rs7072554 chr10:1090988 C/T cg26597838 chr10:835615 NA 0.51 5.71 0.46 7.72e-8 Eosinophil percentage of granulocytes; TGCT cis rs6921919 0.583 rs3734563 chr6:28349725 A/G cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.3 -0.43 5.13e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10465746 0.780 rs12139191 chr1:84387871 A/C cg10977910 chr1:84465055 TTLL7 0.71 7.15 0.54 6.64e-11 Obesity-related traits; TGCT cis rs7223966 1.000 rs61360320 chr17:61800392 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.7 0.39 6.69e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7714584 1.000 rs58717741 chr5:150284936 A/G cg22134413 chr5:150180641 NA 1.02 7.39 0.55 1.89e-11 Crohn's disease; TGCT cis rs9527 0.590 rs12785223 chr10:104844011 C/T cg04362960 chr10:104952993 NT5C2 -0.67 -5.62 -0.45 1.22e-7 Arsenic metabolism; TGCT cis rs1153858 1.000 rs7163720 chr15:45639374 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs986417 1.000 rs1254291 chr14:60863570 A/T cg27398547 chr14:60952738 C14orf39 -1.49 -10.81 -0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs7714584 1.000 rs2217266 chr5:150272621 C/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs2932538 0.922 rs7527076 chr1:113150481 G/A cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs13108904 0.875 rs10024013 chr4:1280792 C/T cg13395646 chr4:1353034 KIAA1530 0.4 4.98 0.41 2.1e-6 Obesity-related traits; TGCT cis rs778371 0.647 rs974321 chr2:233638351 G/A cg08000102 chr2:233561755 GIGYF2 0.69 7.77 0.57 2.62e-12 Schizophrenia; TGCT cis rs7255045 0.788 rs10424001 chr19:12948462 A/G cg23899408 chr19:12877188 HOOK2 -0.58 -4.66 -0.39 7.88e-6 Mean corpuscular volume; TGCT cis rs2153535 0.601 rs7775274 chr6:8530303 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs7511006 0.893 rs760743 chr22:50647375 C/T cg19026356 chr22:50624276 TRABD -0.5 -4.61 -0.38 1e-5 Obesity-related traits; TGCT cis rs7192750 0.586 rs11075908 chr16:71928850 C/T cg06353428 chr16:71660113 MARVELD3 -0.82 -7.56 -0.56 7.85e-12 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs6835098 0.509 rs2332655 chr4:174093002 A/G cg08422745 chr4:174089978 GALNT7 0.66 6.39 0.5 3.02e-9 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg06634786 chr22:41940651 POLR3H 0.9 8.62 0.61 2.67e-14 Vitiligo; TGCT cis rs9788682 0.947 rs12439240 chr15:78829091 T/C cg24631222 chr15:78858424 CHRNA5 0.92 7.54 0.56 8.79e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs763121 0.819 rs8137829 chr22:39061030 G/A cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.9e-12 Menopause (age at onset); TGCT cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg08280861 chr8:58055591 NA 0.49 5.38 0.43 3.64e-7 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.903 rs1118963 chr20:25247449 G/A cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs380904 1.000 rs380904 chr8:144565905 A/G cg22012530 chr8:144635309 GSDMD 0.44 4.56 0.38 1.22e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs936229 0.626 rs3765066 chr15:75140854 G/A cg10253484 chr15:75165896 SCAMP2 -0.83 -7.48 -0.56 1.2e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs7772486 0.790 rs4314514 chr6:146260010 A/G cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 1.000 rs10170359 chr2:26272219 G/T cg04944784 chr2:26401820 FAM59B -0.67 -6.05 -0.48 1.62e-8 Gut microbiome composition (summer); TGCT cis rs875971 0.964 rs697969 chr7:65558478 C/A cg11764359 chr7:65958608 NA -0.58 -4.99 -0.41 2.01e-6 Aortic root size; TGCT cis rs753778 0.602 rs9792 chr8:142205237 C/T cg18755752 chr8:142205143 DENND3 0.28 5.14 0.42 1.04e-6 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7267979 1.000 rs6050609 chr20:25411751 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs459571 0.876 rs2520095 chr9:136919568 A/G cg14405625 chr9:136855902 VAV2 -0.32 -4.79 -0.39 4.71e-6 Platelet distribution width; TGCT cis rs903263 0.965 rs2174186 chr1:84662664 A/G cg09664975 chr1:84543551 PRKACB 0.48 4.6 0.38 1.01e-5 Breast cancer (male); TGCT cis rs7226408 0.857 rs56133445 chr18:34491392 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7829975 0.714 rs6994038 chr8:8660538 C/A cg15556689 chr8:8085844 FLJ10661 0.73 6.67 0.51 7.41e-10 Mood instability; TGCT trans rs7618501 0.633 rs6792892 chr3:49995518 T/C cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.6e-16 Intelligence (multi-trait analysis); TGCT cis rs1670533 0.932 rs10902753 chr4:1056223 G/A cg20887711 chr4:1340912 KIAA1530 0.69 5.48 0.44 2.32e-7 Recombination rate (females); TGCT cis rs8014204 0.748 rs12889277 chr14:75229376 A/T cg06637938 chr14:75390232 RPS6KL1 0.73 6.97 0.53 1.62e-10 Caffeine consumption; TGCT cis rs477895 1.000 rs41294396 chr11:64078581 G/A cg04317338 chr11:64019027 PLCB3 0.71 5.65 0.45 1.05e-7 Mean platelet volume; TGCT cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs11719291 0.915 rs11557629 chr3:48732223 G/A cg00383909 chr3:49044727 WDR6 0.98 5.67 0.45 9.63e-8 Cognitive function; TGCT cis rs7659604 0.702 rs61217486 chr4:122693973 T/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.32 -5.22 -0.42 7.34e-7 Type 2 diabetes; TGCT cis rs9611565 0.592 rs1811113 chr22:42073134 C/T cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Vitiligo; TGCT cis rs4824093 0.535 rs73443931 chr22:50291603 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -6.76 -0.52 4.86e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7772486 0.790 rs4896852 chr6:146284621 T/C cg05347473 chr6:146136440 FBXO30 -0.54 -5.22 -0.42 7.44e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.547 rs9897761 chr17:17912011 A/T cg04398451 chr17:18023971 MYO15A -0.32 -5.07 -0.41 1.44e-6 Total body bone mineral density; TGCT cis rs227917 1.000 rs10240211 chr7:23687039 C/G cg12601843 chr7:23510954 IGF2BP3 0.63 4.86 0.4 3.41e-6 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs763121 0.889 rs1043402 chr22:38879688 G/A cg06022373 chr22:39101656 GTPBP1 0.73 6.92 0.53 2.18e-10 Menopause (age at onset); TGCT cis rs9677476 0.516 rs7607338 chr2:231987955 C/A cg07929768 chr2:232055508 NA 0.34 5.23 0.43 6.91e-7 Food antigen IgG levels; TGCT cis rs8077889 0.672 rs3785810 chr17:41850689 C/G cg26893861 chr17:41843967 DUSP3 1.14 21.11 0.88 7.06e-43 Triglycerides; TGCT cis rs3741151 1.000 rs75004180 chr11:73024739 A/G cg17517138 chr11:73019481 ARHGEF17 1.16 5.48 0.44 2.31e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs9400467 0.537 rs9647629 chr6:111501484 C/T cg15721981 chr6:111408429 SLC16A10 0.71 4.6 0.38 1.04e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs4631830 0.863 rs7081532 chr10:51526093 A/G cg10326726 chr10:51549505 MSMB -0.24 -4.85 -0.4 3.68e-6 Prostate-specific antigen levels; TGCT cis rs6121246 0.909 rs6089070 chr20:30377773 A/G cg13852791 chr20:30311386 BCL2L1 -0.7 -4.86 -0.4 3.53e-6 Mean corpuscular hemoglobin; TGCT cis rs2070488 0.965 rs2366119 chr3:38484453 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs10779751 1.000 rs2016559 chr1:11269917 G/T cg08854313 chr1:11322531 MTOR 0.96 8.97 0.63 3.85e-15 Body mass index; TGCT cis rs2456568 0.867 rs10501810 chr11:93666589 C/G cg14065697 chr11:93583672 C11orf90 -0.38 -4.57 -0.38 1.14e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7830933 0.955 rs13261166 chr8:23594733 A/G cg04349084 chr8:23602677 NA 0.23 4.59 0.38 1.08e-5 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs617219 0.698 rs7445125 chr5:78507417 A/G cg05890484 chr5:78407552 BHMT 0.4 5.46 0.44 2.48e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7943191 0.810 rs7942991 chr11:62337203 A/G cg22862634 chr11:62369728 EML3;MTA2 -0.57 -5.76 -0.46 6.39e-8 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs61935443 0.832 rs11107773 chr12:95282000 C/T cg21533806 chr12:95267307 NA 0.53 4.55 0.38 1.28e-5 Schizophrenia; TGCT trans rs561341 1.000 rs15654 chr17:30326360 A/C cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs4888262 0.545 rs58136167 chr16:74700628 G/A cg01733217 chr16:74700730 RFWD3 0.76 7.64 0.57 5.24e-12 Testicular germ cell tumor; TGCT cis rs7659604 0.502 rs13106764 chr4:122699630 C/G cg19748678 chr4:122722346 EXOSC9 -0.59 -5.82 -0.46 4.81e-8 Type 2 diabetes; TGCT cis rs240764 0.658 rs60658003 chr6:101201191 C/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs10779751 0.770 rs12041740 chr1:11236524 G/A cg08854313 chr1:11322531 MTOR 0.84 8.09 0.59 4.52e-13 Body mass index; TGCT cis rs8180040 0.966 rs13064843 chr3:47415467 C/T cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg04389838 chr3:44770851 ZNF501 -0.42 -5.72 -0.46 7.66e-8 Depressive symptoms; TGCT cis rs9916302 0.821 rs12938268 chr17:37572139 G/A cg15445000 chr17:37608096 MED1 0.35 5.05 0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs950776 0.518 rs2869544 chr15:78839400 G/A cg06917634 chr15:78832804 PSMA4 -0.92 -8.93 -0.63 4.82e-15 Sudden cardiac arrest; TGCT cis rs861020 0.604 rs3766612 chr1:210020013 G/T cg05527609 chr1:210001259 C1orf107 -1.02 -9.26 -0.64 7.82e-16 Orofacial clefts; TGCT cis rs7618915 0.571 rs34954168 chr3:52612159 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs12497850 0.931 rs11705888 chr3:48817289 T/C cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs12477438 0.520 rs4402818 chr2:99717608 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.52 0.61 4.53e-14 Chronic sinus infection; TGCT trans rs11167764 0.623 rs62384602 chr5:141477685 T/G cg18543871 chr19:46281018 DMPK 0.33 6.77 0.52 4.64e-10 Crohn's disease; TGCT cis rs9318086 0.712 rs9318099 chr13:24442462 C/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.77 -8.46 -0.61 6.15e-14 Myopia (pathological); TGCT cis rs769267 0.930 rs7254748 chr19:19397479 A/C cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs2309757 1 rs2309757 chr2:100807725 T/C cg07810366 chr2:100720526 AFF3 -0.39 -5.69 -0.46 8.49e-8 Educational attainment (college completion); TGCT cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg00431813 chr7:1051703 C7orf50 -0.22 -4.7 -0.39 6.93e-6 Longevity;Endometriosis; TGCT cis rs7208859 0.623 rs9911173 chr17:29154750 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9972944 0.692 rs6504346 chr17:63757175 C/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.09 -0.42 1.27e-6 Total body bone mineral density; TGCT cis rs8180040 0.764 rs12630534 chr3:47001043 T/C cg27129171 chr3:47204927 SETD2 0.72 9.42 0.65 3.2e-16 Colorectal cancer; TGCT cis rs6684514 1.000 rs11264462 chr1:156241728 G/A cg20302342 chr1:156215951 PAQR6 0.36 4.75 0.39 5.6e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs4711350 1.000 rs751727 chr6:33764158 A/G cg18005901 chr6:33739558 LEMD2 -0.55 -5.89 -0.47 3.38e-8 Schizophrenia; TGCT cis rs2153535 0.580 rs2152348 chr6:8474301 C/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2288278 0.601 rs7501529 chr17:46598139 G/T cg25032089 chr17:46643351 HOXB3 -0.42 -5.01 -0.41 1.86e-6 Hand grip strength; TGCT cis rs910316 1.000 rs876403 chr14:75602834 A/T cg08847533 chr14:75593920 NEK9 0.95 10.3 0.68 2.33e-18 Height; TGCT cis rs9341808 0.655 rs9350846 chr6:80865481 T/A cg08355045 chr6:80787529 NA 0.31 5.53 0.44 1.79e-7 Sitting height ratio; TGCT cis rs2839186 0.709 rs2156117 chr21:47669300 C/A cg13012494 chr21:47604986 C21orf56 0.35 4.49 0.37 1.61e-5 Testicular germ cell tumor; TGCT cis rs250677 0.687 rs250664 chr5:148453823 C/T cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.888 rs4809468 chr20:61673566 T/C cg08564027 chr20:61660810 NA 0.37 6.0 0.47 2e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs78487399 0.808 rs77852659 chr2:43761652 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.79 4.82 0.4 4.14e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2692947 0.770 rs62153678 chr2:96558346 C/T cg13655245 chr2:97463316 CNNM4 0.15 4.51 0.38 1.51e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9611565 0.644 rs2413652 chr22:42097238 C/T cg17554472 chr22:41940697 POLR3H 0.47 5.02 0.41 1.72e-6 Vitiligo; TGCT cis rs6121246 0.567 rs6058203 chr20:30198979 C/T cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs3096299 0.900 rs3114867 chr16:89428967 A/C cg06640241 chr16:89574553 SPG7 0.6 6.04 0.48 1.68e-8 Multiple myeloma (IgH translocation); TGCT trans rs2760061 0.717 rs708117 chr1:228199902 G/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.21 -0.54 4.89e-11 Diastolic blood pressure; TGCT cis rs916888 0.773 rs199445 chr17:44817408 C/T cg15921436 chr17:44337874 NA 0.56 7.75 0.57 2.88e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs34638657 0.732 rs12102917 chr16:82196808 G/A cg09439754 chr16:82129088 HSD17B2 -0.24 -4.51 -0.38 1.5e-5 Lung adenocarcinoma; TGCT cis rs1008375 1.000 rs10939742 chr4:17659936 G/T cg16339924 chr4:17578868 LAP3 0.63 5.34 0.43 4.26e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs3780486 0.801 rs10971424 chr9:33138775 T/C cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg06753367 chr22:24256600 NA -0.24 -4.64 -0.38 8.75e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7191439 0.728 rs4238687 chr16:88788903 T/G cg27087555 chr16:88793112 FAM38A -0.44 -5.03 -0.41 1.66e-6 Plateletcrit; TGCT cis rs9894429 0.869 rs9748184 chr17:79596280 A/G cg21028142 chr17:79581711 NPLOC4 0.29 6.86 0.52 2.94e-10 Eye color traits; TGCT cis rs921968 0.643 rs4674324 chr2:219523433 T/G cg02176678 chr2:219576539 TTLL4 0.38 5.47 0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs1129187 0.755 rs4714638 chr6:42917017 A/G cg27588902 chr6:42928151 GNMT -0.5 -6.05 -0.48 1.55e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg18538332 chr22:24372958 LOC391322 -1.02 -13.19 -0.76 2.24e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7208859 0.623 rs73269923 chr17:29102571 C/T cg13385521 chr17:29058706 SUZ12P 0.81 4.84 0.4 3.83e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs992157 0.775 rs1877714 chr2:219134928 A/G cg00012203 chr2:219082015 ARPC2 -0.76 -7.33 -0.55 2.64e-11 Colorectal cancer; TGCT cis rs12477438 0.765 rs10181422 chr2:99558970 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.56 -4.74 -0.39 5.78e-6 Chronic sinus infection; TGCT cis rs9393777 0.513 rs13215020 chr6:26656073 G/A cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs4851254 0.961 rs13011181 chr2:100732446 T/C cg23118464 chr2:100721844 AFF3 0.66 4.84 0.4 3.74e-6 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs9393890 chr6:28063855 C/T cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs7258465 1.000 rs7258465 chr19:18533642 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.46 0.37 1.8e-5 Breast cancer; TGCT cis rs7678296 0.649 rs60691639 chr4:37239925 T/C cg06805348 chr4:37245195 KIAA1239 0.57 4.8 0.4 4.49e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg25703541 chr22:24373054 LOC391322 -0.83 -8.57 -0.61 3.53e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1538970 0.781 rs713358 chr1:45988267 C/G cg05343316 chr1:45956843 TESK2 0.72 5.61 0.45 1.25e-7 Platelet count; TGCT cis rs2797160 1.000 rs61299898 chr6:126007651 G/C cg05901451 chr6:126070800 HEY2 0.74 6.3 0.49 4.62e-9 Endometrial cancer; TGCT cis rs9457247 0.967 rs382009 chr6:167403121 G/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs4808199 0.948 rs2301671 chr19:19466269 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.48 0.44 2.24e-7 Nonalcoholic fatty liver disease; TGCT cis rs514406 0.861 rs503296 chr1:53283088 A/G cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs3935685 0.934 rs11072664 chr15:77999859 C/G cg25212270 chr15:78015279 NA 0.3 6.06 0.48 1.48e-8 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs114924396 chr4:119755621 A/G cg14228332 chr4:119757509 SEC24D 1.32 5.99 0.47 2.14e-8 Cannabis dependence symptom count; TGCT cis rs208520 0.690 rs851464 chr6:66839802 C/T cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs7572733 0.534 rs4369854 chr2:198800630 T/C cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs112217694 1.000 rs78970556 chr4:104655040 C/A cg24090629 chr4:104641072 TACR3 -0.97 -4.81 -0.4 4.25e-6 Menarche (age at onset); TGCT cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg23719950 chr11:63933701 MACROD1 -0.71 -5.93 -0.47 2.77e-8 Mean platelet volume; TGCT cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg17554472 chr22:41940697 POLR3H -0.51 -5.26 -0.43 6.08e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9430161 0.579 rs10864486 chr1:11040979 A/G cg02454025 chr1:11042201 C1orf127 0.93 11.7 0.72 9.01e-22 Ewing sarcoma; TGCT cis rs3947 0.951 rs1692819 chr8:11705448 G/A cg02840367 chr8:11660030 FDFT1 0.87 6.58 0.51 1.19e-9 Blood protein levels; TGCT cis rs17384381 0.863 rs12140272 chr1:85789757 G/A cg16011679 chr1:85725395 C1orf52 0.89 6.94 0.53 1.89e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2302045 0.655 rs1056916 chr2:242053526 G/A cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs1005277 0.505 rs200939 chr10:38139483 T/C cg25427524 chr10:38739819 LOC399744 -0.37 -7.41 -0.55 1.74e-11 Extrinsic epigenetic age acceleration; TGCT cis rs10836699 0.562 rs7106759 chr11:37199677 A/G cg18520238 chr11:36422557 PRR5L 0.18 4.52 0.38 1.41e-5 Low high density lipoprotein cholesterol levels; TGCT cis rs36093844 0.898 rs12363602 chr11:85596401 T/A cg25872744 chr11:85566296 CCDC83 -0.52 -4.66 -0.39 7.93e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs11122272 0.735 rs2790891 chr1:231513190 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs950169 0.545 rs4354897 chr15:84644971 T/C cg11189052 chr15:85197271 WDR73 0.63 4.9 0.4 2.94e-6 Schizophrenia; TGCT cis rs7324557 0.684 rs9507165 chr13:24384430 A/C cg16602799 chr13:25254742 ATP12A 0.57 4.45 0.37 1.93e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs12908161 0.959 rs34028043 chr15:85231585 G/A cg12863693 chr15:85201151 NMB 0.46 5.53 0.44 1.79e-7 Schizophrenia; TGCT cis rs854765 0.583 rs8073001 chr17:17831716 A/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.77 -0.39 5.01e-6 Total body bone mineral density; TGCT cis rs2404602 0.716 rs4079681 chr15:76695230 G/A cg22467129 chr15:76604101 ETFA -0.59 -7.13 -0.54 7.47e-11 Blood metabolite levels; TGCT cis rs2290416 0.584 rs3816477 chr8:144685271 T/C cg08017634 chr8:144659831 NAPRT1 -0.48 -4.68 -0.39 7.51e-6 Attention deficit hyperactivity disorder; TGCT cis rs801193 0.660 rs10950049 chr7:66230860 T/C cg18876405 chr7:65276391 NA 0.32 4.71 0.39 6.42e-6 Aortic root size; TGCT cis rs1475911 0.656 rs9980065 chr21:43528072 G/A cg19766460 chr21:43528205 UMODL1;C21orf128 0.84 12.25 0.74 4.22e-23 IgG glycosylation; TGCT cis rs1971762 0.527 rs6580953 chr12:54021138 T/C cg16917193 chr12:54089295 NA 1.07 11.66 0.72 1.17e-21 Height; TGCT cis rs11690935 0.959 rs10204502 chr2:172588866 C/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.51 -0.75 9.78e-24 Schizophrenia; TGCT cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs6725041 0.792 rs10048750 chr2:213090883 C/T cg20637307 chr2:213403960 ERBB4 -0.52 -4.6 -0.38 1.02e-5 QT interval (ambient particulate matter interaction); TGCT cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg08280861 chr8:58055591 NA 0.37 5.0 0.41 1.89e-6 Developmental language disorder (linguistic errors); TGCT cis rs6977660 0.507 rs28402966 chr7:19774469 A/C cg05791153 chr7:19748676 TWISTNB 1.01 6.63 0.51 9.26e-10 Thyroid stimulating hormone; TGCT cis rs9296092 0.560 rs9469500 chr6:33526196 C/T cg13560919 chr6:33536144 NA -0.22 -4.95 -0.41 2.33e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9653442 0.712 rs6749757 chr2:100730111 A/C cg07810366 chr2:100720526 AFF3 0.41 6.71 0.52 6.19e-10 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7635838 0.619 rs347616 chr3:11277927 G/A cg00170343 chr3:11313890 ATG7 0.66 6.26 0.49 5.67e-9 HDL cholesterol; TGCT cis rs9788721 0.630 rs77681598 chr15:78906103 C/A cg06917634 chr15:78832804 PSMA4 -0.65 -5.35 -0.43 4.02e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs877282 0.891 rs10904557 chr10:797490 C/T cg17470449 chr10:769945 NA -0.3 -4.98 -0.41 2.06e-6 Uric acid levels; TGCT cis rs12510870 0.566 rs7696502 chr4:74453404 T/C cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs6121246 0.529 rs750144 chr20:30179027 C/T cg18721089 chr20:30220636 NA 0.63 6.86 0.52 2.95e-10 Mean corpuscular hemoglobin; TGCT cis rs644799 0.544 rs1727165 chr11:95521648 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.57 6.21 0.49 7.25e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7829975 0.545 rs13261926 chr8:8551610 T/C cg06636001 chr8:8085503 FLJ10661 -0.62 -5.28 -0.43 5.56e-7 Mood instability; TGCT cis rs59698941 0.527 rs11742089 chr5:132178930 G/A cg27099455 chr5:132201840 GDF9;UQCRQ 0.28 4.76 0.39 5.3e-6 Apolipoprotein A-IV levels; TGCT cis rs12497850 0.931 rs13064784 chr3:49135961 C/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.66 0.45 9.84e-8 Parkinson's disease; TGCT cis rs908922 0.676 rs6687126 chr1:152530894 T/G cg20991723 chr1:152506922 NA 0.45 6.05 0.48 1.6e-8 Hair morphology; TGCT cis rs1577917 1.000 rs1962716 chr6:86648436 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.61 -4.9 -0.4 2.93e-6 Response to antipsychotic treatment; TGCT cis rs4665809 0.590 rs13016807 chr2:26496186 G/C cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs709400 0.663 rs28444993 chr14:103930564 T/C cg26031613 chr14:104095156 KLC1 0.84 9.53 0.65 1.78e-16 Body mass index; TGCT cis rs2120019 1.000 rs67544533 chr15:75361539 A/G cg11632617 chr15:75315747 PPCDC -0.33 -4.69 -0.39 7.14e-6 Blood trace element (Zn levels); TGCT cis rs17376456 1.000 rs66978370 chr5:93553633 G/A cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.72e-12 Diabetic retinopathy; TGCT cis rs6977955 1.000 rs740122 chr7:28166442 G/A cg23620719 chr7:28220237 JAZF1 0.65 4.96 0.41 2.23e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs344364 0.511 rs1657134 chr16:1953127 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.46 -5.31 -0.43 4.97e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7552404 1.000 rs7516226 chr1:76234257 G/A cg03433033 chr1:76189801 ACADM 0.82 9.46 0.65 2.61e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7914558 0.966 rs1890185 chr10:104748718 A/G cg15744005 chr10:104629667 AS3MT -0.41 -5.08 -0.42 1.33e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3008870 1.000 rs4620509 chr1:67449941 A/G cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs7824557 0.767 rs17797443 chr8:11164012 T/C cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs12216125 0.801 rs56107510 chr6:25987436 C/A cg16482183 chr6:26056742 HIST1H1C 0.64 5.52 0.44 1.9e-7 Iron status biomarkers; TGCT cis rs1997103 1.000 rs6966183 chr7:55407546 A/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs16866061 0.517 rs7594223 chr2:225472985 T/C cg22455342 chr2:225449267 CUL3 0.58 4.87 0.4 3.37e-6 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg24846343 chr22:24311635 DDTL -0.22 -5.9 -0.47 3.29e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4665809 1.000 rs6546726 chr2:26275116 A/G cg04944784 chr2:26401820 FAM59B -0.67 -6.09 -0.48 1.32e-8 Gut microbiome composition (summer); TGCT cis rs5750830 0.649 rs2413590 chr22:39790191 G/C cg01416388 chr22:39784598 NA -0.72 -7.12 -0.54 7.66e-11 Intelligence (multi-trait analysis); TGCT cis rs2932538 0.883 rs7549547 chr1:113086717 A/T cg22162597 chr1:113214053 CAPZA1 0.27 5.89 0.47 3.46e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2486012 1.000 rs2906597 chr1:44406725 A/G cg12908607 chr1:44402522 ARTN 0.78 6.04 0.48 1.68e-8 Intelligence (multi-trait analysis); TGCT cis rs7568458 0.684 rs7579147 chr2:85805654 G/A cg17127132 chr2:85788382 GGCX 0.51 4.57 0.38 1.15e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs12701220 0.803 rs12701432 chr7:1052453 C/T cg27454412 chr7:1067447 C7orf50 -0.5 -4.75 -0.39 5.51e-6 Bronchopulmonary dysplasia; TGCT cis rs2692947 0.631 rs2312954 chr2:96772447 C/T cg22654517 chr2:96458247 NA -0.21 -4.58 -0.38 1.11e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7666738 0.830 rs13125930 chr4:98654695 G/A cg17366294 chr4:99064904 C4orf37 0.62 6.4 0.5 2.94e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4078252 0.720 rs3922585 chr5:112455254 A/C cg04226363 chr5:112043716 APC 0.51 4.6 0.38 1.02e-5 Response to cytadine analogues (cytosine arabinoside); TGCT cis rs295140 1.000 rs10931897 chr2:201162520 T/C cg04283868 chr2:201171347 SPATS2L 0.63 6.39 0.5 3.03e-9 QT interval; TGCT cis rs7599312 0.586 rs7571561 chr2:213386267 T/C cg16329650 chr2:213403929 ERBB4 0.55 4.62 0.38 9.45e-6 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7786808 0.741 rs11769149 chr7:158227127 A/G cg01191920 chr7:158217561 PTPRN2 0.43 6.56 0.51 1.28e-9 Obesity-related traits; TGCT cis rs9653442 1.000 rs11676922 chr2:100806940 T/A cg07810366 chr2:100720526 AFF3 -0.45 -7.79 -0.57 2.34e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs66573146 1.000 rs66573146 chr4:6984464 C/G cg07817883 chr1:32538562 TMEM39B 1.66 8.29 0.6 1.56e-13 Granulocyte percentage of myeloid white cells; TGCT trans rs3780486 0.713 rs3780489 chr9:33129844 G/T cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs10501293 1.000 rs4755698 chr11:43123536 G/T cg03447554 chr11:43094025 NA -0.49 -6.73 -0.52 5.72e-10 Cognitive performance; TGCT cis rs7582180 0.715 rs11123823 chr2:100916315 A/G cg14675211 chr2:100938903 LONRF2 0.47 4.55 0.38 1.24e-5 Intelligence (multi-trait analysis); TGCT cis rs13082711 0.554 rs34066402 chr3:27387987 G/A cg02860705 chr3:27208620 NA 0.43 6.0 0.47 2.03e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs4975616 0.686 rs37008 chr5:1351538 C/T cg07493874 chr5:1342172 CLPTM1L -0.24 -5.13 -0.42 1.07e-6 Lung cancer; TGCT cis rs17108533 0.588 rs12887301 chr14:71301688 C/T cg23900759 chr14:71108106 TTC9 -1.14 -4.44 -0.37 2e-5 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs2486012 0.737 rs1502907 chr1:44258040 A/G cg12908607 chr1:44402522 ARTN -0.71 -5.54 -0.45 1.75e-7 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.935 rs428659 chr6:145827039 T/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs459571 0.959 rs455381 chr9:136905577 C/A cg14405625 chr9:136855902 VAV2 -0.3 -4.55 -0.38 1.28e-5 Platelet distribution width; TGCT cis rs6964587 0.967 rs55801687 chr7:91762629 C/A cg22709100 chr7:91322751 NA 0.29 4.7 0.39 6.9e-6 Breast cancer; TGCT cis rs73198271 0.628 rs75693229 chr8:8590926 G/A ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.22 -0.42 7.19e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1018836 0.608 rs6986165 chr8:91477062 C/G cg16814680 chr8:91681699 NA -0.73 -7.41 -0.55 1.69e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs492146 0.935 rs316137 chr6:52846680 C/A cg06706454 chr6:52930286 FBXO9 -0.47 -4.54 -0.38 1.29e-5 Epilepsy (remission after treatment); TGCT cis rs9990333 0.544 rs112577972 chr3:195825149 T/G cg14488913 chr3:195402182 SDHAP2 -0.36 -4.6 -0.38 1.04e-5 Iron status biomarkers (transferrin levels);Iron status biomarkers (transferrin saturation); TGCT cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg03264133 chr6:25882463 NA -0.62 -6.62 -0.51 9.81e-10 Blood metabolite levels; TGCT cis rs17125944 0.686 rs7143400 chr14:53324891 A/C cg00686598 chr14:53173677 PSMC6 -0.89 -4.62 -0.38 9.56e-6 Alzheimer's disease (late onset); TGCT cis rs3806843 0.576 rs251370 chr5:140246287 C/T cg07102913 chr5:140593443 PCDHB13 0.5 4.76 0.39 5.3e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9325144 0.560 rs7971313 chr12:38653413 A/G cg26384229 chr12:38710491 ALG10B -0.63 -5.92 -0.47 2.9e-8 Morning vs. evening chronotype; TGCT cis rs8051431 0.876 rs1559401 chr16:72011181 G/T cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg04546413 chr19:29218101 NA 0.83 6.68 0.51 7.35e-10 Methadone dose in opioid dependence; TGCT cis rs7474896 0.583 rs10764144 chr10:37975732 G/C cg13720705 chr10:37990370 NA 0.33 4.78 0.39 4.82e-6 Obesity (extreme); TGCT cis rs4665809 1.000 rs1550381 chr2:26266946 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.07 -0.48 1.45e-8 Gut microbiome composition (summer); TGCT cis rs6728642 1.000 rs11890407 chr2:97621647 G/C cg26665480 chr2:98280029 ACTR1B -0.88 -5.22 -0.42 7.31e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs6500602 0.647 rs1684600 chr16:4594671 C/T cg08645402 chr16:4508243 NA -0.18 -5.09 -0.42 1.27e-6 Schizophrenia; TGCT trans rs114540395 0.720 rs79528180 chr10:103218179 C/T cg10198749 chr1:39920707 MACF1 0.55 7.11 0.54 8.11e-11 Schizophrenia; TGCT cis rs155076 0.666 rs4638420 chr13:21872348 A/G cg11317459 chr13:21872234 NA 1.44 13.07 0.76 4.54e-25 White matter hyperintensity burden; TGCT cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg12042659 chr19:58951599 ZNF132 0.51 4.57 0.38 1.18e-5 Uric acid clearance; TGCT cis rs2013441 0.932 rs2526479 chr17:20130221 T/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs9291683 0.597 rs11723016 chr4:10126189 A/G cg00071950 chr4:10020882 SLC2A9 -0.44 -4.84 -0.4 3.73e-6 Bone mineral density; TGCT cis rs79349575 0.811 rs80032154 chr17:47014992 C/A cg27201301 chr17:47039149 GIP 0.26 4.58 0.38 1.12e-5 Type 2 diabetes; TGCT cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg04317338 chr11:64019027 PLCB3 0.75 6.19 0.49 8.06e-9 Mean platelet volume; TGCT cis rs9653442 0.805 rs7608424 chr2:100796543 G/T cg07810366 chr2:100720526 AFF3 -0.47 -7.88 -0.58 1.45e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs308447 0.516 rs6853540 chr4:123679848 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.66 6.42 0.5 2.63e-9 Perceived unattractiveness to mosquitoes; TGCT cis rs4845570 1.000 rs4845356 chr1:151759223 T/A cg07092448 chr1:151763213 TDRKH 1.17 9.52 0.65 1.85e-16 Coronary artery disease; TGCT cis rs78456975 0.527 rs11885279 chr2:1560633 T/C cg01028140 chr2:1542097 TPO -0.33 -5.12 -0.42 1.14e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7647973 1.000 rs3866330 chr3:49582994 T/C cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.76 -0.39 5.24e-6 Menarche (age at onset); TGCT cis rs3125734 0.633 rs7088891 chr10:64034019 G/T cg19640130 chr10:64028056 RTKN2 -0.4 -5.18 -0.42 8.53e-7 Rheumatoid arthritis; TGCT cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg27454412 chr7:1067447 C7orf50 0.55 4.7 0.39 6.89e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs427394 0.802 rs274694 chr5:6734079 A/G cg10857441 chr5:6722123 POLS -0.32 -7.93 -0.58 1.08e-12 Menopause (age at onset); TGCT cis rs13040088 0.935 rs3787513 chr20:61573736 G/A cg23096297 chr20:61557774 DIDO1 1.18 9.71 0.66 6.5e-17 Menopause (age at onset); TGCT cis rs2836633 0.895 rs61085980 chr21:40032140 C/T cg12884169 chr21:40033163 ERG 0.42 4.47 0.37 1.75e-5 Coronary artery disease; TGCT cis rs539096 0.500 rs2906457 chr1:44338575 A/C cg12908607 chr1:44402522 ARTN -0.7 -8.79 -0.62 1.01e-14 Intelligence (multi-trait analysis); TGCT cis rs67478160 0.608 rs34066659 chr14:104263427 A/C cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs9653442 0.545 rs4850921 chr2:100762699 G/T cg22139774 chr2:100720529 AFF3 -0.39 -6.13 -0.48 1.08e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1048238 0.506 rs848210 chr1:16259813 A/G cg21385522 chr1:16154831 NA -0.55 -5.88 -0.47 3.64e-8 Systolic blood pressure; TGCT cis rs3096299 0.719 rs12934708 chr16:89523790 C/T cg02187348 chr16:89574699 SPG7 0.6 6.39 0.5 2.98e-9 Multiple myeloma (IgH translocation); TGCT cis rs2120019 1.000 rs34237279 chr15:75361121 A/G cg11632617 chr15:75315747 PPCDC -0.33 -4.63 -0.38 9.1e-6 Blood trace element (Zn levels); TGCT cis rs9894429 0.646 rs7220310 chr17:79606056 C/A cg21028142 chr17:79581711 NPLOC4 0.29 5.95 0.47 2.56e-8 Eye color traits; TGCT cis rs208520 0.690 rs207118 chr6:66788948 T/A cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs3760982 0.565 rs3786956 chr19:44286829 C/T cg12072164 chr19:44306565 LYPD5 0.4 5.68 0.45 8.91e-8 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs9527 0.590 rs2066322 chr10:104909339 T/G cg15744005 chr10:104629667 AS3MT -0.4 -4.63 -0.38 9.04e-6 Arsenic metabolism; TGCT cis rs6750047 0.719 rs1583171 chr2:38270107 G/A cg07380506 chr2:38303506 CYP1B1 0.59 5.25 0.43 6.35e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs860295 0.529 rs11577179 chr1:155983710 A/G cg05700447 chr1:155978627 NA -0.19 -4.64 -0.38 8.75e-6 Body mass index; TGCT cis rs1448094 0.506 rs61930640 chr12:86173333 T/C cg02569458 chr12:86230093 RASSF9 0.38 4.45 0.37 1.89e-5 Major depressive disorder; TGCT cis rs9660180 0.967 rs10907191 chr1:1774820 A/T cg17747265 chr1:1875780 NA -0.41 -7.74 -0.57 2.95e-12 Body mass index; TGCT cis rs9908158 1 rs9908158 chr17:33890083 T/C cg05299278 chr17:33885742 SLFN14 -0.23 -5.15 -0.42 9.78e-7 Platelet count;Platelet distribution width; TGCT cis rs1552244 0.572 rs68121641 chr3:10165845 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs1799949 0.965 rs7212284 chr17:41205941 A/G cg10047753 chr17:41438598 NA 0.72 6.46 0.5 2.18e-9 Menopause (age at onset); TGCT cis rs9467603 1.000 rs13200921 chr6:25790378 T/C cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.901 rs6826799 chr4:152455700 G/A cg17479576 chr4:152424074 FAM160A1 -0.57 -6.34 -0.49 3.85e-9 Intelligence (multi-trait analysis); TGCT cis rs231513 0.911 rs231525 chr17:41951283 C/T cg26893861 chr17:41843967 DUSP3 -0.87 -6.27 -0.49 5.58e-9 Cognitive function; TGCT cis rs801193 0.660 rs1016265 chr7:66214567 C/T cg11764359 chr7:65958608 NA 0.56 4.81 0.4 4.32e-6 Aortic root size; TGCT cis rs11779988 0.545 rs409217 chr8:17816597 C/G cg01800426 chr8:17659068 MTUS1 -0.61 -4.73 -0.39 5.99e-6 Breast cancer; TGCT cis rs12291225 0.535 rs10832248 chr11:14413087 G/A cg19336497 chr11:14380999 RRAS2 -0.3 -4.63 -0.38 9.21e-6 Sense of smell; TGCT cis rs11690935 0.549 rs2129475 chr2:172916772 A/G cg13550731 chr2:172543902 DYNC1I2 0.69 6.39 0.5 3.06e-9 Schizophrenia; TGCT cis rs909674 0.662 rs2899318 chr22:39837625 A/G cg02038168 chr22:39784481 NA -0.71 -5.35 -0.43 4.03e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs7216064 0.953 rs11079705 chr17:65835452 A/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9457247 1.000 rs448060 chr6:167382622 A/G cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs11792861 0.816 rs11791845 chr9:111683898 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.54 5.13 0.42 1.07e-6 Menarche (age at onset); TGCT cis rs7666738 0.830 rs10021044 chr4:99002488 A/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9915657 0.773 rs9896360 chr17:70099469 C/G cg06234051 chr17:70120541 SOX9 -0.27 -5.65 -0.45 1.05e-7 Thyroid hormone levels; TGCT cis rs7809950 0.954 rs12673675 chr7:107113220 T/C cg23024343 chr7:107201750 COG5 -0.34 -5.43 -0.44 2.89e-7 Coronary artery disease; TGCT cis rs10883723 0.962 rs10883726 chr10:104236276 C/T cg05855489 chr10:104503620 C10orf26 -0.55 -4.68 -0.39 7.42e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs8177253 1.000 rs8177253 chr3:133480192 A/G cg11941060 chr3:133502564 NA 0.29 6.19 0.49 7.94e-9 Iron status biomarkers; TGCT trans rs2727020 0.595 rs7924311 chr11:49507573 G/A cg15704280 chr7:45808275 SEPT13 -0.74 -8.49 -0.61 5.28e-14 Coronary artery disease; TGCT cis rs9902453 0.935 rs9909093 chr17:28271207 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.26 0.6 1.9e-13 Coffee consumption (cups per day); TGCT cis rs2153535 0.580 rs2225765 chr6:8481785 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs873946 0.586 rs3793686 chr10:134569559 A/G cg26818010 chr10:134567672 INPP5A -0.38 -5.37 -0.43 3.66e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs7613875 0.641 rs6446194 chr3:50067298 T/A cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT cis rs479844 0.617 rs12146493 chr11:65547333 G/A cg26683025 chr11:65560420 OVOL1 0.24 4.83 0.4 3.91e-6 Allergic disease (asthma, hay fever or eczema);Atopic march;Atopic dermatitis; TGCT cis rs4849845 0.637 rs2028147 chr2:121058412 C/T cg24070213 chr2:121070622 NA -0.35 -4.64 -0.38 8.58e-6 Mean platelet volume; TGCT cis rs67311347 1.000 rs28871903 chr3:40511094 T/G cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT trans rs2469997 0.925 rs2470010 chr8:120359532 T/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs9814567 1.000 rs1814336 chr3:134200823 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -10.02 -0.67 1.12e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs12776158 0.901 rs12414678 chr10:71214669 C/T cg12610070 chr10:71211762 TSPAN15 -0.59 -5.17 -0.42 9.16e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs7662987 0.540 rs2851257 chr4:100039499 G/C cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs68170813 0.559 rs1548524 chr7:106944563 G/T cg02696742 chr7:106810147 HBP1 0.69 5.87 0.47 3.69e-8 Coronary artery disease; TGCT cis rs11252926 0.550 rs10795122 chr10:466830 C/T cg20256804 chr10:444983 DIP2C -0.21 -4.44 -0.37 1.99e-5 Psychosis in Alzheimer's disease; TGCT cis rs12780845 0.540 rs10490962 chr10:17200363 A/G cg01003015 chr10:17271136 VIM -0.52 -4.71 -0.39 6.42e-6 Homocysteine levels; TGCT cis rs7918232 0.941 rs4749230 chr10:27441218 C/T cg14442939 chr10:27389572 ANKRD26 0.8 5.42 0.44 2.94e-7 Breast cancer; TGCT cis rs7726839 0.507 rs60068988 chr5:597668 T/C cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs7940866 0.809 rs11222410 chr11:130833994 A/G cg12179176 chr11:130786555 SNX19 0.57 5.5 0.44 2.05e-7 Schizophrenia; TGCT cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg20849893 chr7:64541193 NA -0.45 -4.6 -0.38 1.02e-5 Calcium levels; TGCT cis rs4766566 0.694 rs1362006 chr12:111742222 A/G cg10833066 chr12:111807467 FAM109A 0.38 7.32 0.55 2.77e-11 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs9383153 1.000 rs2237223 chr6:16329741 G/A cg06493612 chr6:15502050 JARID2 0.63 4.88 0.4 3.15e-6 Gambling; TGCT cis rs9467773 0.967 rs6932865 chr6:26540166 C/A cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs4689388 0.824 rs4467645 chr4:6294305 C/T cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9534288 0.797 rs9534277 chr13:46578349 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs6906287 0.647 rs3752581 chr6:118869730 G/A cg21191810 chr6:118973309 C6orf204 0.26 4.5 0.38 1.51e-5 Electrocardiographic conduction measures; TGCT cis rs459571 0.920 rs455073 chr9:136909141 G/C cg13789015 chr9:136890014 NCRNA00094 0.41 7.66 0.57 4.51e-12 Platelet distribution width; TGCT cis rs2050392 1.000 rs2253585 chr10:30696503 C/T cg18806716 chr10:30721971 MAP3K8 -0.44 -5.18 -0.42 8.82e-7 Inflammatory bowel disease; TGCT cis rs4642101 0.765 rs9872103 chr3:12827452 G/T cg05775895 chr3:12838266 CAND2 0.79 9.0 0.63 3.36e-15 QRS complex (12-leadsum); TGCT cis rs9914988 0.943 rs12453504 chr17:27119524 C/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs875971 0.830 rs427575 chr7:65519219 A/G cg11764359 chr7:65958608 NA 0.53 4.62 0.38 9.5e-6 Aortic root size; TGCT cis rs7914558 0.966 rs7908280 chr10:104816947 C/G cg15744005 chr10:104629667 AS3MT -0.38 -4.62 -0.38 9.61e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4808199 0.948 rs2301671 chr19:19466269 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.64 4.75 0.39 5.58e-6 Nonalcoholic fatty liver disease; TGCT cis rs4699052 0.963 rs11097804 chr4:104215137 A/T cg16532752 chr4:104119610 CENPE -0.56 -5.05 -0.41 1.57e-6 Testicular germ cell tumor; TGCT cis rs10114408 0.959 rs10739965 chr9:96651479 A/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7703051 0.513 rs59014134 chr5:74589385 C/T cg07671805 chr5:74907694 NA 0.54 4.74 0.39 5.79e-6 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs7647973 0.593 rs59684465 chr3:49874246 C/T cg05785598 chr3:49045655 WDR6 -0.42 -5.23 -0.42 7.1e-7 Menarche (age at onset); TGCT cis rs4499344 0.524 rs259242 chr19:33144248 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.81 7.96 0.58 9.26e-13 Mean platelet volume; TGCT cis rs6456156 0.792 rs4710179 chr6:167513692 G/T cg07741184 chr6:167504864 NA 0.22 4.51 0.38 1.48e-5 Primary biliary cholangitis; TGCT cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg09222892 chr1:25734099 RHCE -0.43 -6.92 -0.53 2.11e-10 Erythrocyte sedimentation rate; TGCT cis rs9810089 0.843 rs681783 chr3:136035303 C/T cg12473912 chr3:136751656 NA 0.35 4.96 0.41 2.28e-6 Gestational age at birth (child effect); TGCT cis rs4595586 0.545 rs3858554 chr12:39381460 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.56 0.38 1.21e-5 Morning vs. evening chronotype; TGCT cis rs2730245 0.959 rs2527201 chr7:158738611 G/T cg24397884 chr7:158709396 WDR60 -0.38 -5.08 -0.42 1.33e-6 Height; TGCT cis rs651907 0.535 rs34161138 chr3:101510388 T/C cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs709400 0.628 rs7155014 chr14:103863970 C/G cg12935359 chr14:103987150 CKB -0.35 -5.26 -0.43 6.08e-7 Body mass index; TGCT cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs1008375 1.000 rs60178264 chr4:17685308 G/T cg18681998 chr4:17616180 MED28 0.92 10.51 0.69 7.15e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4819052 0.851 rs2877020 chr21:46658742 C/T cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7513165 0.935 rs7538038 chr1:204161026 C/T cg12731349 chr1:204159619 KISS1 -0.5 -5.6 -0.45 1.32e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs7523273 1.000 rs7541230 chr1:207957555 T/C cg22525895 chr1:207977042 MIR29B2 -0.48 -8.34 -0.6 1.19e-13 Schizophrenia; TGCT cis rs4975616 0.773 rs414965 chr5:1324121 G/A cg06550200 chr5:1325588 CLPTM1L -0.3 -4.66 -0.39 8.15e-6 Lung cancer; TGCT trans rs7698623 0.850 rs6813016 chr4:88768808 T/C cg01186725 chr1:53905612 FLJ40434 -0.48 -6.62 -0.51 9.94e-10 Cardiovascular disease risk factors; TGCT cis rs12477438 0.765 rs2309521 chr2:99592069 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs7614311 0.636 rs66818634 chr3:63913222 G/A cg22134162 chr3:63841271 THOC7 -0.48 -6.11 -0.48 1.2e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs12681287 0.640 rs7846090 chr8:87467724 A/T cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs483180 0.531 rs539708 chr1:120208503 G/T cg19096424 chr1:120255104 PHGDH -0.57 -5.45 -0.44 2.62e-7 Macular telangiectasia type 2; TGCT cis rs7568458 0.709 rs2043675 chr2:85769975 C/T cg17127132 chr2:85788382 GGCX -0.53 -4.69 -0.39 7.05e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9291683 0.527 rs3822241 chr4:10094931 G/A cg11266682 chr4:10021025 SLC2A9 -0.57 -6.84 -0.52 3.15e-10 Bone mineral density; TGCT cis rs4969178 0.641 rs4969141 chr17:76391653 C/T cg05887092 chr17:76393375 PGS1 0.22 4.66 0.39 8.19e-6 HDL cholesterol levels; TGCT cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2072499 0.966 rs2842882 chr1:156165342 T/G cg25208724 chr1:156163844 SLC25A44 1.14 17.15 0.84 1.56e-34 Testicular germ cell tumor; TGCT cis rs2249625 0.935 rs1852702 chr6:72908366 T/C cg24401219 chr6:72892597 RIMS1 -0.54 -4.52 -0.38 1.43e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs3096299 0.719 rs2965818 chr16:89510494 A/G cg02187348 chr16:89574699 SPG7 0.62 6.65 0.51 8.36e-10 Multiple myeloma (IgH translocation); TGCT cis rs7666738 0.800 rs13107586 chr4:99028788 G/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs3845702 0.935 rs3845695 chr2:180796989 A/G cg01881094 chr2:180872142 CWC22 -0.66 -5.88 -0.47 3.55e-8 Schizophrenia; TGCT cis rs1448094 0.511 rs61930074 chr12:86218759 G/C cg02569458 chr12:86230093 RASSF9 0.36 4.53 0.38 1.36e-5 Major depressive disorder; TGCT cis rs7507204 0.767 rs62125962 chr19:3410852 A/G cg08380311 chr19:3435252 NFIC 0.97 8.14 0.59 3.51e-13 Height; TGCT cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7010267 0.570 rs4495458 chr8:120042780 G/T cg17171407 chr8:119960777 TNFRSF11B 0.25 4.49 0.37 1.59e-5 Total body bone mineral density (age 45-60); TGCT cis rs9486715 1.000 rs9386670 chr6:97060688 C/A cg18709589 chr6:96969512 KIAA0776 -0.82 -7.32 -0.55 2.76e-11 Headache; TGCT cis rs7826238 0.524 rs2921055 chr8:8319342 C/A cg15556689 chr8:8085844 FLJ10661 0.7 6.4 0.5 2.85e-9 Systolic blood pressure; TGCT cis rs12477438 0.520 rs11685759 chr2:99766217 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.47 0.86 2.08e-37 Chronic sinus infection; TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg25151919 chr3:44754333 ZNF502 0.42 4.92 0.4 2.67e-6 Depressive symptoms; TGCT cis rs58235267 0.543 rs2539990 chr2:63170185 C/T cg17519650 chr2:63277830 OTX1 0.7 6.94 0.53 1.9e-10 Prostate-specific antigen levels (conditioned on lead SNPs); TGCT cis rs17376456 0.569 rs896729 chr5:93222178 A/G cg21475434 chr5:93447410 FAM172A -0.69 -5.27 -0.43 5.81e-7 Diabetic retinopathy; TGCT cis rs12497850 0.931 rs9835307 chr3:48857805 T/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs66573146 1.000 rs55672215 chr4:6970529 T/C cg05069807 chr4:6945702 TBC1D14 0.29 4.74 0.39 5.73e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9393777 0.623 rs13211166 chr6:27265940 T/A cg11262757 chr6:27280423 POM121L2 0.62 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs7818688 0.697 rs11783878 chr8:95979261 C/T cg16049864 chr8:95962084 TP53INP1 -0.54 -4.64 -0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs597539 0.616 rs513476 chr11:68698996 C/T cg06112835 chr11:68658793 MRPL21 0.45 7.64 0.57 5.19e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 0.683 rs6982990 chr8:58115275 C/T cg02725872 chr8:58115012 NA 0.36 5.05 0.41 1.53e-6 Developmental language disorder (linguistic errors); TGCT trans rs7618501 1.000 rs35261599 chr3:49773236 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs10779751 0.734 rs12569242 chr1:11127511 A/C cg08854313 chr1:11322531 MTOR 0.81 6.85 0.52 3.09e-10 Body mass index; TGCT cis rs6882046 0.513 rs681446 chr5:88054292 C/T cg24804195 chr5:87968844 LOC645323 0.58 5.57 0.45 1.5e-7 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg27211696 chr2:191398769 TMEM194B 0.29 5.3 0.43 5.19e-7 Pulse pressure; TGCT cis rs910316 0.737 rs175510 chr14:75524839 G/A cg08847533 chr14:75593920 NEK9 -0.83 -8.38 -0.6 9.93e-14 Height; TGCT cis rs1008375 1.000 rs4698200 chr4:17657051 G/A cg18681998 chr4:17616180 MED28 1.0 11.88 0.73 3.32e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs826838 0.967 rs826879 chr12:39088999 A/C cg13010199 chr12:38710504 ALG10B -0.61 -4.98 -0.41 2.06e-6 Heart rate; TGCT cis rs739496 0.579 rs7975437 chr12:112376949 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.36 0.43 3.98e-7 Platelet count; TGCT cis rs611744 0.523 rs13253581 chr8:109343105 A/G cg18478394 chr8:109455254 TTC35 0.44 4.45 0.37 1.85e-5 Dupuytren's disease; TGCT cis rs2180341 0.960 rs1964130 chr6:127677391 C/G cg24812749 chr6:127587940 RNF146 0.82 5.73 0.46 7.1e-8 Breast cancer; TGCT cis rs2153535 0.541 rs6908504 chr6:8456778 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9500256 0.711 rs6588685 chr6:58319653 A/G cg16251399 chr6:58287822 GUSBL2 0.56 4.74 0.39 5.76e-6 Eosinophilic esophagitis (pediatric); TGCT cis rs4478858 0.735 rs4622114 chr1:31772571 A/G cg00250761 chr1:31883323 NA -0.28 -5.01 -0.41 1.86e-6 Alcohol dependence; TGCT trans rs916888 0.773 rs9896243 chr17:44826056 C/G cg22968622 chr17:43663579 NA 1.3 11.87 0.73 3.46e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6138458 1.000 rs227630 chr20:24913584 A/G cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs67072384 0.892 rs72966136 chr11:72456710 G/C cg03713592 chr11:72463424 ARAP1 -0.96 -4.77 -0.39 5.1e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs4665809 1.000 rs750452 chr2:26324995 G/A cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs28735056 0.967 rs61090726 chr18:77631219 A/G cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs1992660 0.523 rs10045016 chr5:40328325 T/A cg01087697 chr5:40835557 RPL37 0.52 4.7 0.39 6.83e-6 Crohn's disease; TGCT cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg23758822 chr17:41437982 NA 0.69 6.76 0.52 4.79e-10 Menopause (age at onset); TGCT cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg13397359 chr6:42928475 GNMT 0.73 6.81 0.52 3.7e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6089829 0.962 rs7267951 chr20:61665979 A/G cg03213289 chr20:61660250 NA 0.7 10.11 0.67 6.94e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs9916302 0.904 rs4794813 chr17:37670994 A/T cg07936489 chr17:37558343 FBXL20 -0.6 -4.75 -0.39 5.45e-6 Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs1365505 0.587 rs4238382 chr15:50484746 T/A cg26188685 chr15:50540269 HDC -0.4 -6.62 -0.51 9.8e-10 Blood metabolite ratios; TGCT cis rs6840360 0.571 rs875667 chr4:152525477 G/A cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs2243480 0.803 rs34004500 chr7:65312178 A/T cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs11711311 1.000 rs2305546 chr3:113503354 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.64 -0.51 8.96e-10 IgG glycosylation; TGCT cis rs2153535 0.580 rs9378554 chr6:8488468 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs62103177 0.513 rs9945153 chr18:77598450 C/T cg12964065 chr18:77638022 KCNG2 0.41 5.48 0.44 2.31e-7 Opioid sensitivity; TGCT cis rs992157 0.710 rs12694432 chr2:219082330 A/G cg00012203 chr2:219082015 ARPC2 0.81 10.19 0.68 4.34e-18 Colorectal cancer; TGCT trans rs1005277 0.602 rs1740743 chr10:38519222 C/T cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs10771431 1.000 rs10771431 chr12:9380859 C/T cg09152401 chr12:9436616 LOC642846 -0.5 -5.18 -0.42 8.57e-7 Breast size; TGCT cis rs57994353 0.600 rs1130640 chr9:139317979 C/T cg13741927 chr9:139327495 INPP5E -0.25 -5.59 -0.45 1.35e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2224391 0.628 rs2773313 chr6:5252213 C/G cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs2013441 0.901 rs2526474 chr17:20137134 C/T cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs600231 0.665 rs1626021 chr11:65226187 A/G cg17120908 chr11:65337727 SSSCA1 -0.51 -4.71 -0.39 6.51e-6 Bone mineral density; TGCT cis rs9527 0.571 rs7904113 chr10:104633114 G/T cg15744005 chr10:104629667 AS3MT -0.46 -5.81 -0.46 4.91e-8 Arsenic metabolism; TGCT cis rs875971 0.522 rs1917563 chr7:65415647 C/T cg18876405 chr7:65276391 NA -0.35 -5.58 -0.45 1.44e-7 Aortic root size; TGCT cis rs13392177 0.543 rs12623716 chr2:219073018 C/T cg00012203 chr2:219082015 ARPC2 -0.78 -7.79 -0.57 2.32e-12 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs10479542 0.701 rs10479541 chr5:178981003 G/C cg05712903 chr5:178977398 RUFY1 0.49 4.64 0.38 8.7e-6 Lung cancer; TGCT cis rs7568458 0.660 rs6547623 chr2:85801964 T/A cg02493740 chr2:85810744 VAMP5 -0.31 -6.11 -0.48 1.19e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs13108904 0.870 rs13110563 chr4:1255772 G/C cg00684032 chr4:1343700 KIAA1530 0.22 4.82 0.4 4.11e-6 Obesity-related traits; TGCT cis rs2204008 0.754 rs11514074 chr12:38401128 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.42 0.55 1.62e-11 Bladder cancer; TGCT cis rs35146811 0.659 rs863450 chr7:99821685 C/T cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs826838 0.904 rs10880981 chr12:38763911 G/A cg13010199 chr12:38710504 ALG10B 0.82 6.86 0.52 2.91e-10 Heart rate; TGCT cis rs17826219 0.706 rs8075107 chr17:29106649 C/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs6906287 0.647 rs28655926 chr6:118688962 A/G cg21191810 chr6:118973309 C6orf204 0.26 4.46 0.37 1.85e-5 Electrocardiographic conduction measures; TGCT cis rs2153535 0.580 rs7341382 chr6:8470549 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs40363 0.951 rs250632 chr16:3523047 C/T cg00484396 chr16:3507460 NAT15 0.42 5.18 0.42 8.85e-7 Tuberculosis; TGCT cis rs17376456 0.597 rs11135401 chr5:93365716 G/A cg21475434 chr5:93447410 FAM172A -0.64 -5.99 -0.47 2.14e-8 Diabetic retinopathy; TGCT cis rs12950390 0.853 rs56137679 chr17:45862112 C/G cg24803719 chr17:45855879 NA -0.49 -5.03 -0.41 1.64e-6 IgG glycosylation; TGCT cis rs6840360 0.593 rs3805356 chr4:152680701 C/T cg17479576 chr4:152424074 FAM160A1 0.52 5.2 0.42 7.86e-7 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs35076545 chr6:26603924 C/A cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs950169 0.887 rs12903946 chr15:84954430 T/C cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg08859206 chr1:53392774 SCP2 -0.46 -7.42 -0.55 1.64e-11 Monocyte count; TGCT cis rs10744422 1.000 rs4759387 chr12:123377569 C/T cg25930673 chr12:123319894 HIP1R -0.85 -5.09 -0.42 1.29e-6 Schizophrenia; TGCT cis rs9611565 0.512 rs2899347 chr22:42158204 T/C cg06634786 chr22:41940651 POLR3H 0.86 8.01 0.58 7.16e-13 Vitiligo; TGCT cis rs10832169 0.967 rs11023063 chr11:14068571 T/C cg04547675 chr11:13986162 SPON1 0.54 4.73 0.39 6.08e-6 Blood protein levels; TGCT cis rs2153535 0.580 rs6905242 chr6:8471799 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.07 0.41 1.43e-6 Motion sickness; TGCT cis rs7937682 0.883 rs510388 chr11:111451869 G/T cg09085632 chr11:111637200 PPP2R1B 0.97 10.05 0.67 9.82e-18 Primary sclerosing cholangitis; TGCT cis rs12477438 0.501 rs11688004 chr2:99735052 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs4664308 1.000 rs925410 chr2:160912652 C/T cg03641300 chr2:160917029 PLA2R1 0.26 6.53 0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs55823223 0.702 rs3785437 chr17:73906222 G/T cg08125733 chr17:73851984 WBP2 1.0 6.33 0.49 4.16e-9 Psoriasis; TGCT trans rs1496653 0.602 rs13100499 chr3:23491444 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs367943 0.965 rs458044 chr5:112797779 A/G cg12552261 chr5:112820674 MCC -0.24 -4.92 -0.4 2.7e-6 Type 2 diabetes; TGCT cis rs6543140 0.601 rs7558013 chr2:102992806 G/T cg09003973 chr2:102972529 NA 0.75 6.15 0.48 1e-8 Blood protein levels; TGCT cis rs6121246 0.529 rs2889528 chr20:30210021 C/T cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs2933343 0.661 rs2630259 chr3:128606322 C/T cg11901034 chr3:128598214 ACAD9 -0.68 -6.63 -0.51 9.16e-10 IgG glycosylation; TGCT cis rs2012796 0.665 rs72703728 chr14:81834523 G/A cg02996355 chr14:81879375 NA 0.55 5.55 0.45 1.69e-7 Night sleep phenotypes; TGCT cis rs9916302 0.861 rs11658219 chr17:37709782 G/A cg07936489 chr17:37558343 FBXL20 -0.57 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs453301 0.564 rs28649568 chr8:8959671 T/G cg15556689 chr8:8085844 FLJ10661 -0.72 -5.99 -0.47 2.16e-8 Joint mobility (Beighton score); TGCT cis rs13108904 0.517 rs7671242 chr4:1339875 G/A cg13395646 chr4:1353034 KIAA1530 -0.56 -7.34 -0.55 2.41e-11 Obesity-related traits; TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg22166914 chr1:53195759 ZYG11B -0.37 -6.37 -0.5 3.34e-9 Monocyte count; TGCT cis rs35306767 0.953 rs12354639 chr10:963681 G/A cg26597838 chr10:835615 NA 0.63 9.1 0.63 1.93e-15 Eosinophil percentage of granulocytes; TGCT cis rs514406 0.861 rs1749907 chr1:53259658 C/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs8062405 1.000 rs62036621 chr16:28833299 C/A cg09754948 chr16:28834200 ATXN2L 0.61 4.54 0.38 1.34e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg25703541 chr22:24373054 LOC391322 0.95 12.0 0.73 1.7e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg01802117 chr1:53393560 SCP2 -0.42 -5.25 -0.43 6.33e-7 Monocyte count; TGCT cis rs13256369 1.000 rs7820159 chr8:8576215 T/C cg17143192 chr8:8559678 CLDN23 0.62 5.8 0.46 5.1e-8 Obesity-related traits; TGCT cis rs2836974 0.965 rs34578707 chr21:40675167 G/A cg17971929 chr21:40555470 PSMG1 0.93 8.97 0.63 3.91e-15 Cognitive function; TGCT cis rs3812049 0.784 rs2250127 chr5:127388844 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.59 -5.41 -0.44 3.14e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs727563 0.520 rs132773 chr22:42031768 T/A cg03806693 chr22:41940476 POLR3H 1.06 11.19 0.71 1.58e-20 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg06221963 chr1:154839813 KCNN3 -0.71 -11.67 -0.72 1.1e-21 Prostate cancer; TGCT cis rs2046867 0.862 rs62251646 chr3:72805787 T/C cg25664220 chr3:72788482 NA -0.57 -7.16 -0.54 6.2e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs854765 0.547 rs8075189 chr17:17901946 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.41 0.6 8.09e-14 Total body bone mineral density; TGCT cis rs6831352 0.734 rs3018046 chr4:100030388 C/T cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs5769765 1.000 rs8184990 chr22:50273174 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs6938 0.534 rs8025447 chr15:75192222 T/G cg10253484 chr15:75165896 SCAMP2 -0.55 -5.07 -0.41 1.43e-6 Breast cancer; TGCT cis rs4378999 0.660 rs7627266 chr3:50962368 C/T ch.3.1075622R chr3:50010873 RBM6 0.37 4.62 0.38 9.62e-6 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); TGCT cis rs1843834 0.505 rs4674911 chr2:225345254 A/G cg12698349 chr2:225449008 CUL3 0.76 6.26 0.49 5.79e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.41 2.55e-6 Obesity-related traits; TGCT cis rs67311347 0.869 rs7646899 chr3:40366982 A/G cg13683864 chr3:40499215 RPL14 -1.05 -10.95 -0.7 6.12e-20 Renal cell carcinoma; TGCT trans rs9929218 0.551 rs9888942 chr16:68727572 A/G cg04657470 chr2:198365150 HSPE1;HSPD1 0.59 7.75 0.57 2.78e-12 Colorectal cancer; TGCT trans rs877282 0.755 rs2790388 chr10:786084 T/C cg22713356 chr15:30763199 NA 0.94 8.1 0.59 4.33e-13 Uric acid levels; TGCT cis rs1868673 0.708 rs13066779 chr3:150169379 G/C cg24290546 chr3:150134309 TSC22D2 -0.24 -4.6 -0.38 1.03e-5 Waist circumference; TGCT cis rs2235642 0.717 rs9937922 chr16:1658154 C/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.65 -0.39 8.32e-6 Coronary artery disease; TGCT cis rs478304 0.934 rs1193692 chr11:65504069 A/C cg27068330 chr11:65405492 SIPA1 0.74 7.3 0.55 3.07e-11 Acne (severe); TGCT cis rs655029 0.645 rs633323 chr2:31463044 A/T cg14018959 chr2:31480232 EHD3 -0.32 -4.45 -0.37 1.92e-5 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs6901250 0.655 rs1398403 chr6:117122646 T/C cg12892004 chr6:117198278 RFX6 0.46 5.59 0.45 1.37e-7 C-reactive protein levels; TGCT cis rs7246657 0.943 rs1015849 chr19:37946180 G/A cg18154014 chr19:37997991 ZNF793 0.95 6.52 0.51 1.58e-9 Coronary artery calcification; TGCT cis rs9457247 1.000 rs439237 chr6:167391392 A/G cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs854765 0.583 rs7222480 chr17:17818817 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.91 0.58 1.2e-12 Total body bone mineral density; TGCT cis rs1008375 0.931 rs2098151 chr4:17577490 T/C cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6840360 0.593 rs10013612 chr4:152693622 A/G cg22705602 chr4:152727874 NA -0.34 -5.9 -0.47 3.24e-8 Intelligence (multi-trait analysis); TGCT cis rs929596 0.793 rs2741044 chr2:234579368 G/A cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.29 -4.48 -0.37 1.66e-5 Total bilirubin levels in HIV-1 infection; TGCT trans rs9951602 0.512 rs8084836 chr18:76647841 A/G cg02800362 chr5:177631904 HNRNPAB 1.11 12.65 0.75 4.66e-24 Obesity-related traits; TGCT cis rs7552404 0.690 rs2029681 chr1:76333846 G/A cg10523679 chr1:76189770 ACADM -0.67 -6.27 -0.49 5.47e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs875971 0.522 rs56028712 chr7:65466565 C/T cg00343986 chr7:65444356 GUSB 0.26 5.96 0.47 2.4e-8 Aortic root size; TGCT cis rs1577917 0.958 rs6900436 chr6:86506288 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs2549003 1.000 rs2549002 chr5:131829578 C/A cg02551604 chr5:131831745 NA 0.9 12.39 0.74 2e-23 Asthma (sex interaction); TGCT cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg13397359 chr6:42928475 GNMT 0.74 6.83 0.52 3.33e-10 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs7726839 0.561 rs72703058 chr5:584519 G/A cg25482853 chr8:67687455 SGK3 1.07 8.9 0.62 5.55e-15 Obesity-related traits; TGCT cis rs8180040 0.967 rs17411375 chr3:47395135 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.63 -0.61 2.53e-14 Colorectal cancer; TGCT cis rs7914558 0.869 rs10883842 chr10:104941589 C/T cg15744005 chr10:104629667 AS3MT -0.39 -4.75 -0.39 5.53e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4253772 0.550 rs11703564 chr22:46722194 G/A cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs4568518 0.530 rs11764965 chr7:17998750 A/T cg03009463 chr7:17980271 SNX13 0.57 4.51 0.38 1.47e-5 Measles; TGCT cis rs4919694 0.808 rs4918001 chr10:105013147 G/T cg04362960 chr10:104952993 NT5C2 -1.02 -6.91 -0.53 2.3e-10 Arsenic metabolism; TGCT cis rs9910055 0.762 rs6503489 chr17:42246289 G/A cg13607699 chr17:42295918 UBTF 0.84 7.76 0.57 2.72e-12 Total body bone mineral density; TGCT cis rs1784581 0.894 rs1784594 chr6:162382734 A/G cg17173639 chr6:162384350 PARK2 -0.5 -9.26 -0.64 7.99e-16 Itch intensity from mosquito bite; TGCT cis rs4788570 0.616 rs11075901 chr16:71790812 A/C cg06353428 chr16:71660113 MARVELD3 1.53 12.17 0.74 6.57e-23 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg22963979 chr7:1858916 MAD1L1 0.43 7.32 0.55 2.8e-11 Bipolar disorder and schizophrenia; TGCT cis rs9902453 0.845 rs3102556 chr17:28042542 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.57 5.14 0.42 1.03e-6 Height; TGCT trans rs916888 0.821 rs199504 chr17:44861003 C/T cg01341218 chr17:43662625 NA -1.11 -9.42 -0.65 3.27e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6831352 0.959 rs1139490 chr4:100045141 C/T cg12011299 chr4:100065546 ADH4 0.41 5.09 0.42 1.3e-6 Alcohol dependence; TGCT cis rs3749237 0.557 rs7631908 chr3:49425707 T/G cg02487422 chr3:49467188 NICN1 0.59 6.01 0.47 1.92e-8 Resting heart rate; TGCT cis rs10992471 0.729 rs6479418 chr9:95064762 G/A cg14631576 chr9:95140430 CENPP -0.29 -4.77 -0.39 5.06e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9902453 0.765 rs2467334 chr17:28135508 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.83 -7.95 -0.58 9.99e-13 Coffee consumption (cups per day); TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs6684514 0.961 rs11264469 chr1:156276746 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.43 0.37 2.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7044106 0.664 rs7861679 chr9:123375589 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.6 -6.61 -0.51 1.01e-9 Hip circumference adjusted for BMI; TGCT cis rs7727544 0.684 rs272893 chr5:131663062 T/C cg24060327 chr5:131705240 SLC22A5 -0.57 -6.22 -0.49 6.92e-9 Blood metabolite levels; TGCT cis rs1552244 1.000 rs6442150 chr3:10122575 T/C cg00149659 chr3:10157352 C3orf10 0.95 6.09 0.48 1.3e-8 Alzheimer's disease; TGCT cis rs3782455 1.000 rs79831570 chr12:114401608 T/C cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1729951 0.575 rs361237 chr3:136702414 A/G cg12473912 chr3:136751656 NA 0.38 6.23 0.49 6.63e-9 Neuroticism; TGCT cis rs3849570 1.000 rs3772882 chr3:81808602 C/A cg07356753 chr3:81810745 GBE1 -0.7 -6.08 -0.48 1.4e-8 Waist circumference;Body mass index; TGCT cis rs6429082 0.714 rs184108 chr1:235646160 A/G cg26050004 chr1:235667680 B3GALNT2 0.62 5.58 0.45 1.43e-7 Adiposity; TGCT cis rs6750047 0.771 rs1056837 chr2:38298150 A/G cg07380506 chr2:38303506 CYP1B1 0.66 5.99 0.47 2.14e-8 Cutaneous malignant melanoma;Melanoma; TGCT cis rs2050392 0.687 rs608693 chr10:30734971 G/A cg13289132 chr10:30722225 MAP3K8 -0.43 -5.06 -0.41 1.46e-6 Inflammatory bowel disease; TGCT cis rs763121 0.853 rs5995610 chr22:39064681 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs9859260 0.744 rs492288 chr3:195784210 C/T cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs807669 0.586 rs5746671 chr22:19160899 A/G cg02655711 chr22:19163373 SLC25A1 0.27 5.35 0.43 4.14e-7 Metabolite levels; TGCT cis rs2836950 0.520 rs8133927 chr21:40689961 G/T cg11890956 chr21:40555474 PSMG1 -0.65 -5.97 -0.47 2.27e-8 Menarche (age at onset); TGCT cis rs2862064 0.932 rs1393208 chr5:156477725 G/A cg12943317 chr5:156479607 HAVCR1 -0.46 -5.59 -0.45 1.35e-7 Platelet count; TGCT cis rs4654899 0.865 rs6691824 chr1:21417577 T/G cg01072550 chr1:21505969 NA -0.47 -7.03 -0.53 1.22e-10 Superior frontal gyrus grey matter volume; TGCT cis rs561341 0.700 rs2074101 chr17:30228656 G/A cg13647721 chr17:30228624 UTP6 0.6 5.33 0.43 4.5e-7 Hip circumference adjusted for BMI; TGCT cis rs909674 0.865 rs5757682 chr22:39848259 T/G cg02038168 chr22:39784481 NA -0.72 -5.54 -0.45 1.75e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6076065 0.748 rs4815198 chr20:23343491 T/C cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs7937612 1.000 rs10892566 chr11:120241923 T/C cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.62 -0.38 9.34e-6 Intraocular pressure; TGCT cis rs3733585 0.673 rs4407505 chr4:9953367 T/G cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs938554 0.513 rs10939650 chr4:9998440 C/T cg00071950 chr4:10020882 SLC2A9 0.57 5.32 0.43 4.76e-7 Blood metabolite levels; TGCT cis rs2933343 0.729 rs1680785 chr3:128644816 C/T cg11901034 chr3:128598214 ACAD9 -0.65 -6.05 -0.48 1.55e-8 IgG glycosylation; TGCT cis rs9858542 0.951 rs1800668 chr3:49395757 G/A cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg23283495 chr1:209979779 IRF6 0.65 5.53 0.44 1.81e-7 Cleft lip with or without cleft palate; TGCT cis rs6840360 0.642 rs2724574 chr4:152381800 A/T cg17479576 chr4:152424074 FAM160A1 0.6 6.19 0.49 8.23e-9 Intelligence (multi-trait analysis); TGCT cis rs901683 0.702 rs78757497 chr10:46161918 T/C cg09623279 chr10:45395734 NA -0.49 -5.18 -0.42 8.87e-7 Red blood cell traits;Mean corpuscular volume; TGCT cis rs2836950 0.545 rs2836952 chr21:40616651 G/C cg06238570 chr21:40685208 BRWD1 -0.61 -6.29 -0.49 5.07e-9 Menarche (age at onset); TGCT cis rs12477438 0.765 rs1115757 chr2:99660146 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs589448 0.933 rs523398 chr12:69752775 C/T cg14784868 chr12:69753453 YEATS4 0.9 10.55 0.69 5.67e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs9467773 0.626 rs9379860 chr6:26370605 T/C cg15659132 chr6:26577336 NA -0.53 -5.47 -0.44 2.37e-7 Intelligence (multi-trait analysis); TGCT cis rs9372253 0.818 rs2207360 chr6:110706337 G/C cg19196401 chr6:110721138 DDO -0.42 -5.81 -0.46 4.95e-8 Platelet distribution width; TGCT cis rs2549003 1.000 rs3846732 chr5:131816087 T/C cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs975752 0.717 rs2281949 chr10:102006402 C/T cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs854765 0.624 rs12952723 chr17:17731651 T/C cg04398451 chr17:18023971 MYO15A 0.31 4.72 0.39 6.19e-6 Total body bone mineral density; TGCT cis rs270601 0.661 rs10036208 chr5:131571323 T/C cg24060327 chr5:131705240 SLC22A5 -0.61 -6.37 -0.5 3.32e-9 Acylcarnitine levels; TGCT trans rs1814175 0.817 rs3974439 chr11:50022607 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs13064411 0.696 rs6783965 chr3:113198722 C/T cg18753928 chr3:113234510 CCDC52 -0.69 -5.57 -0.45 1.47e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs782590 0.608 rs10207590 chr2:55921782 G/C cg18811423 chr2:55921094 PNPT1 -0.69 -7.52 -0.56 9.44e-12 Metabolic syndrome; TGCT cis rs2153535 0.580 rs1360054 chr6:8520377 C/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg25703541 chr22:24373054 LOC391322 -0.81 -8.83 -0.62 8.31e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9916302 0.904 rs8076546 chr17:37555403 G/A cg15445000 chr17:37608096 MED1 -0.34 -4.8 -0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs7727544 0.716 rs72793283 chr5:131566941 G/A cg24060327 chr5:131705240 SLC22A5 -0.57 -5.23 -0.43 6.84e-7 Blood metabolite levels; TGCT cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg12386194 chr3:101231763 SENP7 0.6 5.58 0.45 1.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2486288 0.656 rs11854325 chr15:45548959 T/C cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs2016266 0.820 rs11170496 chr12:53666195 G/A cg16917193 chr12:54089295 NA 0.64 5.26 0.43 6.11e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg04317338 chr11:64019027 PLCB3 0.73 6.33 0.49 4.15e-9 Mean platelet volume; TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg01802117 chr1:53393560 SCP2 -0.41 -4.74 -0.39 5.73e-6 Monocyte count; TGCT cis rs610932 0.517 rs673141 chr11:59975710 C/T cg18570331 chr11:60101691 MS4A6E 0.52 4.84 0.4 3.79e-6 Alzheimer's disease; TGCT cis rs9517313 0.615 rs4772079 chr13:99090837 C/G cg20487152 chr13:99095054 FARP1 -0.25 -4.76 -0.39 5.29e-6 Neuroticism; TGCT cis rs6450176 0.909 rs10940353 chr5:53299959 A/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs6969780 0.915 rs3801320 chr7:27164364 C/A cg04317399 chr7:27170313 HOXA4 0.44 4.87 0.4 3.3e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT trans rs1814175 0.817 rs1794164 chr11:49899610 T/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.02 -0.58 6.85e-13 Height; TGCT cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.57 -5.41 -0.44 3.08e-7 Menarche (age at onset); TGCT cis rs9911578 0.967 rs9894274 chr17:56977919 G/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs72861689 chr3:40435890 A/G cg13683864 chr3:40499215 RPL14 -1.12 -12.12 -0.74 8.6e-23 Renal cell carcinoma; TGCT cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg12437481 chr16:420112 MRPL28 -0.54 -5.32 -0.43 4.72e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs4689388 0.926 rs10010131 chr4:6292915 A/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs916888 0.821 rs199509 chr17:44858728 G/A cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs835154 0.817 rs835157 chr5:14874533 T/C cg14843632 chr5:14870594 ANKH 0.33 4.57 0.38 1.16e-5 Blood metabolite levels; TGCT cis rs909341 0.537 rs13041528 chr20:62385446 C/G cg14758556 chr20:62440591 NA -0.37 -5.68 -0.45 9.25e-8 Atopic dermatitis; TGCT cis rs35146811 0.735 rs11767968 chr7:99790971 G/A cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs7772486 0.622 rs1292333 chr6:145982344 C/T cg23711669 chr6:146136114 FBXO30 -0.85 -9.48 -0.65 2.24e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7044106 0.734 rs10491784 chr9:123432289 A/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.47 0.5 2.01e-9 Hip circumference adjusted for BMI; TGCT cis rs6681544 0.760 rs3790889 chr1:82412600 C/T cg04226724 chr1:82268649 LPHN2 0.46 4.74 0.39 5.8e-6 Metabolite levels (X-11787); TGCT cis rs7191700 0.674 rs12597893 chr16:11426331 A/G cg00044050 chr16:11439710 C16orf75 0.9 10.96 0.7 5.73e-20 Multiple sclerosis; TGCT cis rs981844 0.753 rs62325149 chr4:154728006 G/C cg14289246 chr4:154710475 SFRP2 1.04 9.67 0.66 8.17e-17 Response to statins (LDL cholesterol change); TGCT cis rs904251 0.523 rs10807184 chr6:37483713 C/T cg08126542 chr6:37504118 NA -0.43 -6.2 -0.49 7.72e-9 Cognitive performance; TGCT cis rs36051895 0.695 rs7045000 chr9:5015143 G/A cg02405213 chr9:5042618 JAK2 -0.76 -10.18 -0.67 4.62e-18 Pediatric autoimmune diseases; TGCT cis rs4478037 1.000 rs4076086 chr3:33161898 C/T cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs57590327 0.679 rs7639135 chr3:81608976 C/T cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs4665809 1.000 rs4665811 chr2:26260017 A/G cg25036284 chr2:26402008 FAM59B -0.56 -4.85 -0.4 3.62e-6 Gut microbiome composition (summer); TGCT cis rs42648 0.837 rs10262603 chr7:89909442 G/A cg25739043 chr7:89950458 NA -0.73 -7.29 -0.55 3.15e-11 Homocysteine levels; TGCT cis rs6912958 0.684 rs6931069 chr6:88367082 C/T cg06598631 chr6:88300029 RARS2;ORC3L -0.52 -4.8 -0.4 4.57e-6 Monocyte percentage of white cells; TGCT cis rs3791556 1.000 rs13031713 chr2:240118868 C/T cg03281426 chr2:240109471 HDAC4 0.28 4.46 0.37 1.82e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2576037 0.583 rs4890343 chr18:44540969 G/A cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.78 -0.39 4.94e-6 Personality dimensions; TGCT cis rs6964587 0.967 rs2040499 chr7:91809657 C/G cg22709100 chr7:91322751 NA -0.29 -4.68 -0.39 7.51e-6 Breast cancer; TGCT cis rs10927875 0.632 rs10927864 chr1:16165661 C/G cg14742211 chr1:16348397 CLCNKA -0.19 -4.58 -0.38 1.1e-5 Dilated cardiomyopathy; TGCT cis rs6088580 0.634 rs6142164 chr20:33006597 C/T cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs3820928 0.874 rs2272198 chr2:227893017 A/G cg11843606 chr2:227700838 RHBDD1 0.56 5.22 0.42 7.24e-7 Pulmonary function; TGCT cis rs13256369 1.000 rs885000 chr8:8568875 G/T cg17143192 chr8:8559678 CLDN23 0.58 5.56 0.45 1.56e-7 Obesity-related traits; TGCT cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg26513180 chr16:89883248 FANCA 0.76 7.61 0.56 5.85e-12 Vitiligo; TGCT cis rs2458413 0.586 rs2669453 chr8:105368930 C/A cg13045555 chr8:105342365 NA 0.34 4.71 0.39 6.47e-6 Paget's disease; TGCT cis rs6570726 0.791 rs370654 chr6:145879005 C/G cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs8180040 0.874 rs11130123 chr3:47285912 A/G cg27129171 chr3:47204927 SETD2 0.69 8.59 0.61 3.04e-14 Colorectal cancer; TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg17178900 chr1:205818956 PM20D1 -0.54 -6.85 -0.52 3.1e-10 Menarche (age at onset); TGCT cis rs3892630 0.824 rs35700505 chr19:33325006 C/T cg22980127 chr19:33182716 NUDT19 0.72 5.22 0.42 7.45e-7 Red blood cell traits; TGCT cis rs9859260 0.614 rs493661 chr3:195786489 T/A cg22891161 chr3:195456627 MUC20 0.23 4.62 0.38 9.28e-6 Mean corpuscular volume; TGCT cis rs10782582 0.564 rs17647711 chr1:76241710 C/G cg03433033 chr1:76189801 ACADM -0.45 -4.6 -0.38 1.02e-5 Daytime sleep phenotypes; TGCT cis rs651907 0.535 rs11717638 chr3:101505468 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs3096299 0.642 rs12934829 chr16:89523349 T/A cg02187348 chr16:89574699 SPG7 0.63 6.77 0.52 4.54e-10 Multiple myeloma (IgH translocation); TGCT cis rs7666738 0.830 rs11723283 chr4:99001617 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10984561 0.881 rs12238498 chr9:122249067 T/C cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs2404602 0.716 rs56351018 chr15:76824591 T/C cg26408565 chr15:76604113 ETFA -0.4 -5.24 -0.43 6.54e-7 Blood metabolite levels; TGCT cis rs1568889 1.000 rs78140392 chr11:28203231 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.82 8.31 0.6 1.42e-13 Bipolar disorder; TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg16325326 chr1:53192061 ZYG11B 0.52 5.84 0.46 4.24e-8 Monocyte count; TGCT cis rs910316 0.737 rs28687415 chr14:75495482 T/C cg08847533 chr14:75593920 NEK9 0.83 8.74 0.62 1.4e-14 Height; TGCT cis rs10540 1.000 rs61876326 chr11:467368 A/G cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs7570971 0.792 rs56369224 chr2:136328890 A/T cg07169764 chr2:136633963 MCM6 0.53 4.81 0.4 4.22e-6 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs6074578 0.679 rs11087791 chr20:140506 A/G cg16931068 chr20:139680 DEFB127 0.27 4.64 0.38 8.57e-6 Hirschsprung disease; TGCT cis rs1488864 1.000 rs4758408 chr11:6348639 T/C cg12755421 chr11:6342214 PRKCDBP -0.56 -4.48 -0.37 1.7e-5 Smooth-surface caries; TGCT cis rs4824093 0.610 rs13340054 chr22:50311726 G/A cg20569369 chr22:51173646 NA 0.29 4.56 0.38 1.19e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6433895 1.000 rs12999974 chr2:182019537 G/A cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.78e-5 Lymphocyte counts; TGCT cis rs8017423 0.647 rs4904680 chr14:90822075 C/T cg04374321 chr14:90722782 PSMC1 -0.54 -5.2 -0.42 7.91e-7 Mortality in heart failure; TGCT cis rs9311474 0.629 rs13081028 chr3:52555316 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.57 -5.67 -0.45 9.64e-8 Electroencephalogram traits; TGCT cis rs40363 1.000 rs1690441 chr16:3517635 C/G cg00484396 chr16:3507460 NAT15 0.43 5.05 0.41 1.51e-6 Tuberculosis; TGCT cis rs12615966 0.932 rs1947308 chr2:105391930 G/A cg16465502 chr2:105461796 NA 0.78 5.01 0.41 1.83e-6 Pancreatic cancer; TGCT cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs2760061 0.583 rs708118 chr1:228201801 A/G cg02753203 chr1:228287806 NA -0.34 -6.94 -0.53 1.92e-10 Diastolic blood pressure; TGCT cis rs1008375 0.933 rs6847966 chr4:17634255 G/A cg16339924 chr4:17578868 LAP3 0.71 5.75 0.46 6.46e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11785400 0.793 rs11543967 chr8:143739435 A/G cg24634471 chr8:143751801 JRK -0.55 -5.51 -0.44 1.99e-7 Schizophrenia; TGCT cis rs597539 0.690 rs552517 chr11:68625286 T/G cg06028808 chr11:68637592 NA 0.55 6.88 0.53 2.61e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1062177 0.826 rs2915822 chr5:151130901 G/T cg00977110 chr5:151150581 G3BP1 -0.41 -4.74 -0.39 5.73e-6 Preschool internalizing problems; TGCT cis rs1552244 1.000 rs17032295 chr3:10086680 C/T cg00149659 chr3:10157352 C3orf10 0.9 6.34 0.49 3.96e-9 Alzheimer's disease; TGCT cis rs67311347 1.000 rs7642552 chr3:40424816 T/C cg17264618 chr3:40429014 ENTPD3 0.32 4.65 0.39 8.52e-6 Renal cell carcinoma; TGCT cis rs7617773 0.539 rs13094496 chr3:48387050 G/C cg11946769 chr3:48343235 NME6 0.57 4.83 0.4 3.9e-6 Coronary artery disease; TGCT cis rs3820068 0.603 rs2236215 chr1:15892415 A/C cg05660106 chr1:15850417 CASP9 1.1 13.34 0.77 9.88e-26 Systolic blood pressure; TGCT cis rs11809207 0.855 rs17257155 chr1:26526439 C/T cg03844060 chr1:26490628 NA -0.26 -4.81 -0.4 4.28e-6 Height; TGCT cis rs6570726 0.791 rs10872577 chr6:145900560 G/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 1.000 rs1117367 chr15:76872330 A/C cg22467129 chr15:76604101 ETFA -0.44 -4.94 -0.41 2.5e-6 Blood metabolite levels; TGCT cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.89 0.4 3e-6 Platelet count; TGCT cis rs904251 0.797 rs1757177 chr6:37486370 C/T cg01843034 chr6:37503916 NA -0.54 -6.29 -0.49 4.93e-9 Cognitive performance; TGCT cis rs2066819 1.000 rs78495928 chr12:56635080 G/C cg26714650 chr12:56694279 CS -1.32 -6.2 -0.49 7.69e-9 Psoriasis vulgaris; TGCT cis rs854765 1.000 rs854765 chr17:18012730 T/C cg00306284 chr17:18855313 SLC5A10 -0.24 -4.48 -0.37 1.68e-5 Total body bone mineral density; TGCT cis rs7914558 1.000 rs10786733 chr10:104794947 G/A cg15744005 chr10:104629667 AS3MT -0.37 -4.48 -0.37 1.64e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4891159 0.790 rs7241485 chr18:74122325 C/T cg24786174 chr18:74118243 ZNF516 -0.61 -9.12 -0.63 1.68e-15 Longevity; TGCT cis rs9611565 0.500 rs10775759 chr22:42088158 T/C cg17554472 chr22:41940697 POLR3H 0.5 5.36 0.43 3.92e-7 Vitiligo; TGCT cis rs137699 0.652 rs137707 chr22:39751401 T/C cg11247378 chr22:39784982 NA -0.6 -5.94 -0.47 2.68e-8 IgG glycosylation; TGCT trans rs561341 1.000 rs72825740 chr17:30338356 A/G cg20587970 chr11:113659929 NA -1.04 -12.68 -0.75 3.82e-24 Hip circumference adjusted for BMI; TGCT cis rs7312933 0.501 rs7296357 chr12:42729891 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.59 -5.7 -0.46 8.16e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9393777 0.582 rs6936561 chr6:26640895 C/T cg15659132 chr6:26577336 NA -0.77 -5.48 -0.44 2.26e-7 Intelligence (multi-trait analysis); TGCT cis rs4568518 0.502 rs4543441 chr7:17983297 C/T cg03009463 chr7:17980271 SNX13 0.54 4.53 0.38 1.38e-5 Measles; TGCT cis rs7547997 0.615 rs114657189 chr1:158318340 G/C cg07950803 chr1:158223934 CD1A 0.32 5.08 0.42 1.35e-6 QRS duration; TGCT cis rs17221829 0.549 rs7114659 chr11:89383424 A/G cg02982614 chr11:89391479 FOLH1B -0.28 -4.99 -0.41 1.95e-6 Anxiety in major depressive disorder; TGCT cis rs739496 0.542 rs10219736 chr12:111788402 C/T cg10833066 chr12:111807467 FAM109A 0.44 7.47 0.56 1.24e-11 Platelet count; TGCT cis rs1153858 1.000 rs1049508 chr15:45653592 A/G cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs7975161 0.630 rs7978101 chr12:104630510 A/G cg25273343 chr12:104657179 TXNRD1 -0.36 -5.16 -0.42 9.71e-7 Toenail selenium levels; TGCT cis rs763121 0.853 rs3827357 chr22:39079413 A/G cg06022373 chr22:39101656 GTPBP1 0.74 7.31 0.55 2.94e-11 Menopause (age at onset); TGCT cis rs7267979 0.966 rs2424715 chr20:25420077 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7635838 0.718 rs2594979 chr3:11381910 T/G cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs2702888 0.503 rs2741714 chr8:6759967 C/A cg26795848 chr8:6756730 NA -0.32 -6.67 -0.51 7.62e-10 Blood pressure; TGCT cis rs6433857 0.657 rs2368177 chr2:181501242 T/C cg23363182 chr2:181467187 NA -0.33 -5.08 -0.42 1.33e-6 Body mass index; TGCT cis rs9398235 1.000 rs9398235 chr6:110732116 A/G cg19196401 chr6:110721138 DDO -0.5 -4.92 -0.4 2.64e-6 Systemic lupus erythematosus; TGCT cis rs6547741 0.844 rs9678851 chr2:27887034 C/A cg27432699 chr2:27873401 GPN1 -0.24 -6.06 -0.48 1.5e-8 Oral cavity cancer; TGCT cis rs546131 0.600 rs525202 chr11:34821948 A/C cg06937548 chr11:34938143 PDHX;APIP 0.56 4.91 0.4 2.79e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7267979 0.933 rs11699203 chr20:25435169 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7043114 0.525 rs7023004 chr9:95098712 A/G cg14631576 chr9:95140430 CENPP -0.28 -4.75 -0.39 5.47e-6 Height; TGCT cis rs6089584 1.000 rs6089591 chr20:60570548 A/C cg06108461 chr20:60628389 TAF4 -0.54 -7.59 -0.56 6.66e-12 Body mass index; TGCT cis rs959260 0.557 rs55762977 chr17:73309338 A/G cg14668889 chr17:73230827 NUP85 0.21 4.57 0.38 1.14e-5 Systemic lupus erythematosus; TGCT cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg20302342 chr1:156215951 PAQR6 0.37 5.49 0.44 2.19e-7 Tonsillectomy; TGCT cis rs72945132 0.562 rs7951959 chr11:70234272 A/G cg00319359 chr11:70116639 PPFIA1 0.98 7.02 0.53 1.28e-10 Coronary artery disease; TGCT cis rs2859741 1.000 rs2795009 chr1:37509494 C/T cg09363841 chr1:37513479 NA -0.2 -4.54 -0.38 1.33e-5 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs7727544 0.571 rs12521097 chr5:131575338 G/A cg22598563 chr5:131563921 P4HA2 -0.29 -4.57 -0.38 1.15e-5 Blood metabolite levels; TGCT cis rs975752 0.867 rs7924284 chr10:102018089 A/G cg04750910 chr10:102416409 NA -0.73 -4.48 -0.37 1.69e-5 Schizophrenia; TGCT cis rs13242816 1.000 rs13243017 chr7:116189371 G/A cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1552244 1.000 rs9849434 chr3:10133710 A/G cg00149659 chr3:10157352 C3orf10 -0.91 -6.1 -0.48 1.27e-8 Alzheimer's disease; TGCT trans rs3780486 0.505 rs10758188 chr9:33123386 C/T cg04842962 chr6:43655489 MRPS18A -0.8 -8.43 -0.6 7.22e-14 IgG glycosylation; TGCT cis rs780096 0.565 rs11681351 chr2:27743423 G/A cg12000995 chr2:27665139 KRTCAP3 -0.38 -4.53 -0.38 1.39e-5 Total body bone mineral density; TGCT cis rs2574985 0.530 rs7071603 chr10:52272007 C/T cg12753529 chr10:51525504 NA 0.23 4.61 0.38 9.69e-6 Subjective well-being; TGCT cis rs11264213 0.591 rs399393 chr1:36553673 A/G cg27506609 chr1:36549197 TEKT2 -0.5 -5.7 -0.46 8.17e-8 Schizophrenia; TGCT cis rs9388451 0.807 rs1268065 chr6:126042783 G/A cg05901451 chr6:126070800 HEY2 0.98 12.62 0.75 5.47e-24 Brugada syndrome; TGCT cis rs13191362 1.000 rs73008453 chr6:163013384 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg08392591 chr16:89556376 ANKRD11 0.53 4.93 0.41 2.53e-6 Multiple myeloma (IgH translocation); TGCT cis rs4919694 1.000 rs11191439 chr10:104638723 C/T cg04362960 chr10:104952993 NT5C2 -1.03 -6.19 -0.49 7.93e-9 Arsenic metabolism; TGCT cis rs492146 0.902 rs316136 chr6:52846769 T/C cg06706454 chr6:52930286 FBXO9 -0.47 -4.54 -0.38 1.29e-5 Epilepsy (remission after treatment); TGCT cis rs7647973 1.000 rs73088137 chr3:49448423 G/A cg07636037 chr3:49044803 WDR6 -0.72 -5.72 -0.46 7.47e-8 Menarche (age at onset); TGCT cis rs860554 0.511 rs1772828 chr1:201290217 C/T cg01022117 chr1:201258280 PKP1 -0.27 -4.91 -0.4 2.77e-6 Panic disorder; TGCT cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.96 8.05 0.59 5.7e-13 Platelet count; TGCT cis rs3008870 1.000 rs2755246 chr1:67488984 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.02 10.0 0.67 1.26e-17 Lymphocyte percentage of white cells; TGCT cis rs4506170 1.000 rs72712335 chr8:128338258 G/A cg07795030 chr8:128802207 NA -0.21 -4.61 -0.38 9.7e-6 Prostate cancer; TGCT cis rs6121246 0.909 rs8126355 chr20:30332660 C/T cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT trans rs1499614 0.831 rs3800822 chr7:66147149 A/G cg07424592 chr7:64974309 NA -1.35 -8.11 -0.59 4.14e-13 Gout; TGCT cis rs1629083 0.967 rs1715449 chr11:118128455 G/A cg16594165 chr11:118135105 MPZL2 -0.33 -4.62 -0.38 9.51e-6 Lung cancer; TGCT cis rs3774830 0.649 rs41268643 chr4:5469916 G/A cg26943120 chr4:5472116 STK32B 0.28 6.34 0.49 3.97e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7208859 0.673 rs11654914 chr17:29229424 C/G cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7267979 1.000 rs6115182 chr20:25410259 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7613875 0.641 rs6793528 chr3:50100188 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs7223966 0.691 rs9893518 chr17:62006997 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 4.8 0.4 4.48e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs28595532 0.764 rs115916994 chr4:119688758 A/G cg14228332 chr4:119757509 SEC24D 1.02 5.06 0.41 1.47e-6 Cannabis dependence symptom count; TGCT trans rs1496653 0.544 rs71322201 chr3:23623769 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs4253772 0.530 rs9627387 chr22:46684678 A/G cg24881330 chr22:46731750 TRMU 0.96 6.38 0.5 3.18e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs7565124 0.955 rs11674278 chr2:20266381 C/T cg00462460 chr2:20212509 MATN3 -0.43 -4.66 -0.39 8.1e-6 Major depressive disorder; TGCT cis rs7144547 0.950 rs8004137 chr14:81884857 A/G cg02996355 chr14:81879375 NA -0.72 -7.7 -0.57 3.81e-12 Prudent dietary pattern; TGCT cis rs9952991 0.883 rs11663253 chr18:12789556 A/G cg23598886 chr18:12777645 NA -0.62 -5.5 -0.44 2.11e-7 Inflammatory skin disease; TGCT cis rs698761 0.505 rs7609180 chr2:44538484 A/G cg23552047 chr2:44669647 C2orf34 0.29 4.68 0.39 7.33e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs939658 0.683 rs1474256 chr15:79463847 C/T cg17916960 chr15:79447300 NA 0.42 6.67 0.51 7.59e-10 Refractive error; TGCT cis rs514406 0.825 rs497535 chr1:53284677 A/G cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs35374984 0.920 rs16930800 chr10:30234268 A/C cg22629853 chr10:30638455 MTPAP 0.59 5.43 0.44 2.87e-7 Emphysema distribution in smoking; TGCT cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.44 0.56 1.45e-11 Platelet count; TGCT cis rs875971 1.000 rs2042133 chr7:65931922 A/G cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs7917772 0.565 rs61869210 chr10:104437175 A/C cg05855489 chr10:104503620 C10orf26 -0.68 -5.56 -0.45 1.61e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6964587 0.967 rs10953063 chr7:91576958 A/G cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs6088580 0.634 rs6087577 chr20:32955423 C/T cg08999081 chr20:33150536 PIGU 0.26 5.21 0.42 7.67e-7 Glomerular filtration rate (creatinine); TGCT cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg05025164 chr4:1340916 KIAA1530 -0.84 -7.26 -0.55 3.66e-11 Longevity; TGCT cis rs9929218 0.906 rs4783565 chr16:68750190 G/A cg01251360 chr16:68772225 CDH1 0.3 5.0 0.41 1.88e-6 Colorectal cancer; TGCT cis rs986417 0.892 rs57925468 chr14:60816129 G/A cg27398547 chr14:60952738 C14orf39 -1.5 -8.03 -0.58 6.38e-13 Gut microbiota (bacterial taxa); TGCT cis rs651907 0.535 rs36060163 chr3:101360963 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.01 0.41 1.8e-6 Colorectal cancer; TGCT cis rs7651736 0.835 rs6439679 chr3:136757463 C/T cg12473912 chr3:136751656 NA -0.37 -5.76 -0.46 6.22e-8 Neuroticism; TGCT cis rs2742417 1.000 rs938363 chr3:45746364 T/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs807669 1.000 rs807670 chr22:19154608 A/C cg02655711 chr22:19163373 SLC25A1 0.31 6.88 0.53 2.57e-10 Metabolite levels; TGCT cis rs35160687 1.000 rs35160687 chr2:86472114 C/T cg03171300 chr2:86307199 POLR1A 0.33 5.61 0.45 1.25e-7 Night sleep phenotypes; TGCT cis rs4253772 0.591 rs6008384 chr22:46655948 T/C cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.56 4.52 0.38 1.44e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs1005277 0.579 rs2472182 chr10:38388865 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9653442 1.000 rs6712515 chr2:100806514 T/C cg07810366 chr2:100720526 AFF3 -0.52 -8.96 -0.63 4.09e-15 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3091242 0.933 rs3093584 chr1:25668714 T/C cg00786635 chr1:25594202 NA -0.55 -5.64 -0.45 1.07e-7 Erythrocyte sedimentation rate; TGCT cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs71435601 0.628 rs312944 chr2:21325188 A/T cg25035485 chr2:21266500 APOB 0.52 4.48 0.37 1.7e-5 Cholesterol, total; TGCT cis rs317689 0.690 rs604168 chr12:69671158 C/T cg14784868 chr12:69753453 YEATS4 0.53 4.51 0.38 1.5e-5 Response to diuretic therapy; TGCT cis rs7829975 0.514 rs2920991 chr8:8259117 T/A cg06636001 chr8:8085503 FLJ10661 0.69 6.02 0.48 1.81e-8 Mood instability; TGCT cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs7819412 0.745 rs4841498 chr8:10985432 C/T cg21775007 chr8:11205619 TDH -0.51 -4.83 -0.4 3.87e-6 Triglycerides; TGCT cis rs7586879 0.681 rs6752483 chr2:25120086 C/T cg01884057 chr2:25150051 NA 0.35 6.74 0.52 5.27e-10 Body mass index; TGCT cis rs9393692 0.875 rs9358917 chr6:26284417 T/C cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT cis rs12497850 0.931 rs9311434 chr3:48884147 T/C cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs9467711 0.606 rs9366656 chr6:26434630 T/C cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs8141529 0.719 rs6005916 chr22:29233342 T/C cg02153584 chr22:29168773 CCDC117 0.63 5.35 0.43 4.06e-7 Lymphocyte counts; TGCT cis rs11690935 0.686 rs10165126 chr2:172820315 C/T cg13550731 chr2:172543902 DYNC1I2 -0.63 -5.29 -0.43 5.3e-7 Schizophrenia; TGCT cis rs6815814 0.731 rs10776483 chr4:38775040 A/G cg02016764 chr4:38805732 TLR1 -0.28 -4.79 -0.4 4.63e-6 Breast cancer; TGCT cis rs9522267 0.535 rs56330641 chr13:112233538 C/T cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs1018836 0.798 rs28568272 chr8:91652958 A/G cg16814680 chr8:91681699 NA -0.94 -11.83 -0.73 4.43e-22 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs78487399 0.710 rs57381820 chr2:43626668 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -4.87 -0.4 3.39e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12681288 0.862 rs2701899 chr8:1019581 G/A cg21347738 chr8:1310380 NA -0.22 -4.54 -0.38 1.3e-5 Schizophrenia; TGCT cis rs367615 0.879 rs56689485 chr5:108879828 A/T cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6089829 0.962 rs6062777 chr20:61663748 G/A cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs1371867 0.846 rs1692007 chr8:101268343 T/C cg06002616 chr8:101225028 SPAG1 0.53 6.42 0.5 2.67e-9 Atrioventricular conduction; TGCT cis rs10791323 0.628 rs2853117 chr11:133705266 T/G cg03690763 chr11:133734501 NA -0.35 -5.44 -0.44 2.78e-7 Childhood ear infection; TGCT cis rs11105298 0.786 rs3803128 chr12:89860319 C/A cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs8014252 0.711 rs59044667 chr14:71043704 A/G cg11204974 chr14:71022665 NA -0.54 -4.44 -0.37 2e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs10779751 0.770 rs2261434 chr1:11170131 A/C cg08854313 chr1:11322531 MTOR 0.83 8.02 0.58 6.7e-13 Body mass index; TGCT cis rs28595532 0.920 rs17257945 chr4:119666465 T/A cg21605333 chr4:119757512 SEC24D 1.4 7.94 0.58 1.04e-12 Cannabis dependence symptom count; TGCT cis rs7572733 0.534 rs1518363 chr2:198810131 C/T cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs9527 0.590 rs11191578 chr10:104902337 A/T cg04362960 chr10:104952993 NT5C2 0.68 5.76 0.46 6.3e-8 Arsenic metabolism; TGCT cis rs7819412 0.511 rs2409797 chr8:11433780 T/C cg21775007 chr8:11205619 TDH -0.52 -4.79 -0.4 4.63e-6 Triglycerides; TGCT cis rs4285028 0.747 rs11916169 chr3:121403211 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.33 -0.55 2.54e-11 Multiple sclerosis; TGCT cis rs1008375 0.544 rs7685265 chr4:17568510 C/T cg18681998 chr4:17616180 MED28 0.77 6.79 0.52 4.06e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28595532 0.925 rs56200441 chr4:119497440 T/G cg11846333 chr4:119757529 SEC24D 0.93 5.08 0.42 1.32e-6 Cannabis dependence symptom count; TGCT cis rs9291683 0.692 rs1558489 chr4:10325489 T/A cg00071950 chr4:10020882 SLC2A9 -0.43 -4.48 -0.37 1.66e-5 Bone mineral density; TGCT cis rs4665809 1.000 rs6546768 chr2:26328800 A/G cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs9814567 0.929 rs13088413 chr3:134309977 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 9.14 0.63 1.54e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9527 0.569 rs10786730 chr10:104724200 G/A cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs912057 1.000 rs1294410 chr6:6738752 C/T cg06612196 chr6:6737390 NA -0.39 -4.89 -0.4 3.11e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9560113 0.919 rs11069896 chr13:112178887 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs6657613 0.869 rs761421 chr1:17313654 C/T cg21692666 chr1:17199302 NA -0.42 -4.52 -0.38 1.43e-5 Hip circumference adjusted for BMI; TGCT cis rs2839186 0.708 rs6518285 chr21:47644667 T/C cg13732083 chr21:47605072 C21orf56 0.37 4.81 0.4 4.36e-6 Testicular germ cell tumor; TGCT cis rs8016982 0.611 rs11159493 chr14:81639159 A/T cg01989461 chr14:81687754 GTF2A1 0.78 7.47 0.56 1.26e-11 Schizophrenia; TGCT cis rs9611565 0.592 rs5758427 chr22:42099688 A/G cg13695892 chr22:41940480 POLR3H 0.89 9.04 0.63 2.55e-15 Vitiligo; TGCT cis rs16921914 0.559 rs2985140 chr11:31315886 C/T cg14844989 chr11:31128820 NA 0.23 4.56 0.38 1.23e-5 Bone mineral density (spine); TGCT cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs2456568 0.867 rs10501810 chr11:93666589 C/G cg26875233 chr11:93583750 C11orf90 -0.44 -5.49 -0.44 2.18e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6951245 0.542 rs28460147 chr7:1217192 G/A cg23708337 chr7:1209742 NA 0.63 5.87 0.47 3.79e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836633 0.929 rs62217518 chr21:40033189 T/G cg05519781 chr21:40033154 ERG 0.7 6.95 0.53 1.86e-10 Coronary artery disease; TGCT cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs6988636 1.000 rs28600861 chr8:124189063 C/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT trans rs8073060 0.505 rs225270 chr17:33968871 A/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12210905 1.000 rs12209800 chr6:27189517 C/T cg08851530 chr6:28072375 NA -1.04 -5.0 -0.41 1.88e-6 Hip circumference adjusted for BMI; TGCT cis rs734999 0.869 rs61054170 chr1:2498052 C/T cg18854424 chr1:2615690 NA 0.47 5.75 0.46 6.57e-8 Ulcerative colitis; TGCT cis rs116095464 0.558 rs28729548 chr5:229025 C/T cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT trans rs7613875 0.600 rs2247510 chr3:50126215 A/C cg21659725 chr3:3221576 CRBN 0.69 7.57 0.56 7.35e-12 Body mass index; TGCT cis rs7208859 0.673 rs9891413 chr17:29208209 G/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1552244 0.554 rs3732963 chr3:10048885 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs9682041 0.867 rs6444925 chr3:170123358 G/T cg07589077 chr3:170072950 NA 0.33 4.7 0.39 6.82e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT trans rs208520 1.000 rs9453663 chr6:66976077 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.82 7.48 0.56 1.21e-11 Exhaled nitric oxide output; TGCT cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg24531977 chr5:56204891 C5orf35 -0.74 -6.99 -0.53 1.51e-10 Initial pursuit acceleration; TGCT trans rs12599106 0.629 rs1391904 chr16:34548934 C/T cg07332563 chr6:291687 DUSP22 -0.67 -6.76 -0.52 4.77e-10 Menopause (age at onset); TGCT cis rs3857536 0.505 rs208459 chr6:66911055 C/T cg07460842 chr6:66804631 NA -0.68 -6.73 -0.52 5.5e-10 Blood trace element (Cu levels); TGCT cis rs12478296 0.901 rs67951957 chr2:243004901 A/G cg06360820 chr2:242988706 NA -0.64 -5.35 -0.43 4.15e-7 Obesity-related traits; TGCT cis rs7917772 0.536 rs4919667 chr10:104426011 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.83 -8.36 -0.6 1.07e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs425277 0.606 rs2459984 chr1:2086312 A/G cg03732007 chr1:2071316 PRKCZ 0.28 6.76 0.52 4.87e-10 Height; TGCT cis rs6912958 0.781 rs6454632 chr6:88231824 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs3806843 0.576 rs246074 chr5:140307969 C/G cg07102913 chr5:140593443 PCDHB13 -0.46 -4.59 -0.38 1.08e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs17376456 1.000 rs58734583 chr5:93532155 C/T cg25358565 chr5:93447407 FAM172A 0.93 7.91 0.58 1.22e-12 Diabetic retinopathy; TGCT cis rs4654899 1.000 rs6426669 chr1:21430584 C/A cg01072550 chr1:21505969 NA -0.51 -8.1 -0.59 4.46e-13 Superior frontal gyrus grey matter volume; TGCT cis rs1023500 0.505 rs134891 chr22:42675882 T/C cg15557168 chr22:42548783 NA -0.21 -4.94 -0.41 2.47e-6 Schizophrenia; TGCT cis rs1552244 0.572 rs66514627 chr3:10166632 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.63 6.3 0.49 4.63e-9 Menarche (age at onset); TGCT trans rs17780086 0.527 rs17182651 chr17:30547537 G/A cg20587970 chr11:113659929 NA -0.89 -7.15 -0.54 6.46e-11 Height; TGCT cis rs4642101 0.824 rs9835677 chr3:12845158 G/A cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs9388451 0.874 rs9398787 chr6:126090608 A/G cg10911889 chr6:126070802 HEY2 0.54 5.64 0.45 1.08e-7 Brugada syndrome; TGCT cis rs4266144 0.558 rs4680339 chr3:156835419 G/T cg05091238 chr3:157813609 NA -0.48 -5.17 -0.42 9.23e-7 Coronary artery disease; TGCT cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg02353165 chr6:42928485 GNMT 0.95 9.72 0.66 5.91e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12257961 0.549 rs11259612 chr10:15382469 C/T cg10616319 chr10:15468812 NA -0.26 -4.86 -0.4 3.44e-6 Selective IgA deficiency; TGCT cis rs9928842 0.765 rs6564220 chr16:75224194 T/C cg09066997 chr16:75300724 BCAR1 0.26 4.61 0.38 9.91e-6 Alcoholic chronic pancreatitis; TGCT cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.85 -9.0 -0.63 3.25e-15 Intelligence (multi-trait analysis); TGCT cis rs9581857 0.547 rs75800999 chr13:28055293 A/G cg22138327 chr13:27999177 GTF3A 0.74 4.84 0.4 3.81e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg10802521 chr3:52805072 NEK4 -0.74 -9.17 -0.64 1.27e-15 Bipolar disorder; TGCT cis rs2692947 0.702 rs7604842 chr2:96777340 C/T cg05933789 chr2:97190408 NA -0.17 -5.13 -0.42 1.07e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs853679 0.599 rs188015 chr6:27877446 T/A cg10876282 chr6:28092338 ZSCAN16 0.77 4.74 0.39 5.85e-6 Depression; TGCT cis rs4654899 0.571 rs6692677 chr1:21251717 C/T cg01072550 chr1:21505969 NA -0.54 -8.8 -0.62 9.96e-15 Superior frontal gyrus grey matter volume; TGCT trans rs6762477 0.748 rs34877766 chr3:50234126 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.78 7.81 0.57 2.12e-12 Menarche (age at onset); TGCT cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg27454412 chr7:1067447 C7orf50 0.55 4.7 0.39 6.89e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7267979 1.000 rs6037105 chr20:25374199 C/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1395 0.744 rs62130709 chr2:27505782 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 8.02 0.58 6.76e-13 Blood metabolite levels; TGCT cis rs561341 0.602 rs114562703 chr17:30233899 G/T cg13647721 chr17:30228624 UTP6 0.61 4.71 0.39 6.65e-6 Hip circumference adjusted for BMI; TGCT cis rs2692947 0.666 rs10183151 chr2:96774786 T/G cg22654517 chr2:96458247 NA -0.22 -4.81 -0.4 4.27e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs796364 0.662 rs11687313 chr2:201146399 G/A cg19045956 chr2:200819837 C2orf60;C2orf47 -0.67 -4.68 -0.39 7.3e-6 Schizophrenia; TGCT cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg18654377 chr3:49208889 KLHDC8B -0.37 -4.91 -0.4 2.78e-6 Menarche (age at onset); TGCT cis rs6701037 0.512 rs2285216 chr1:175133012 C/T cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs12497850 1.000 rs12493578 chr3:48730116 C/T cg06212747 chr3:49208901 KLHDC8B -0.63 -5.95 -0.47 2.51e-8 Parkinson's disease; TGCT cis rs769267 1.000 rs3764567 chr19:19440066 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.68 -5.94 -0.47 2.62e-8 Tonsillectomy; TGCT cis rs7786808 0.608 rs9692003 chr7:158204696 G/A cg01191920 chr7:158217561 PTPRN2 0.39 5.79 0.46 5.52e-8 Obesity-related traits; TGCT cis rs8013055 0.898 rs8014913 chr14:105977313 T/C cg19700328 chr14:106028568 NA -0.53 -5.91 -0.47 3.03e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs501916 0.833 rs11855134 chr15:48047676 A/G cg16110827 chr15:48056943 SEMA6D -0.16 -4.45 -0.37 1.91e-5 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs13242816 1.000 rs3801994 chr7:116190469 G/A cg16553024 chr7:116138462 CAV2 -0.45 -5.3 -0.43 5.1e-7 P wave duration; TGCT cis rs1018836 0.632 rs7017630 chr8:91482604 A/G cg16814680 chr8:91681699 NA -0.77 -7.9 -0.58 1.3e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6427419 0.934 rs3768538 chr1:158066042 A/G cg07184316 chr1:157669111 FCRL3 0.26 4.75 0.39 5.42e-6 Obesity-related traits; TGCT cis rs3617 0.532 rs9836499 chr3:52904524 G/T cg10802521 chr3:52805072 NEK4 0.57 6.62 0.51 9.79e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg18735214 chr6:43276756 CRIP3 -0.56 -4.89 -0.4 3.05e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1949733 0.675 rs2688235 chr4:8450546 T/C cg13073564 chr4:8508604 NA -0.41 -4.56 -0.38 1.19e-5 Response to antineoplastic agents; TGCT cis rs394563 0.726 rs6942381 chr6:149662991 G/C cg03678062 chr6:149772716 ZC3H12D 0.41 5.31 0.43 4.84e-7 Dupuytren's disease; TGCT cis rs2455799 0.573 rs2455812 chr3:15734096 C/G cg16303742 chr3:15540471 COLQ -0.25 -4.75 -0.39 5.41e-6 Mean platelet volume; TGCT trans rs561341 0.824 rs1978115 chr17:30220776 A/C cg20587970 chr11:113659929 NA -0.79 -9.27 -0.64 7.44e-16 Hip circumference adjusted for BMI; TGCT cis rs4455778 0.659 rs10233118 chr7:49058781 C/T cg26309511 chr7:48887640 NA 0.43 5.27 0.43 5.74e-7 Lung cancer in never smokers; TGCT cis rs6500602 0.701 rs4785968 chr16:4535307 T/A cg08645402 chr16:4508243 NA 0.2 4.98 0.41 2.09e-6 Schizophrenia; TGCT trans rs7965364 0.651 rs7307747 chr12:25498629 C/T cg03116648 chr22:50192934 BRD1 -0.46 -6.64 -0.51 8.93e-10 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6582630 0.622 rs11831595 chr12:38511489 C/A cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7681440 0.904 rs1822217 chr4:90765052 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT trans rs7726839 0.540 rs11738281 chr5:662547 T/C cg11887960 chr12:57824829 NA 1.14 9.54 0.65 1.65e-16 Obesity-related traits; TGCT cis rs7681440 0.835 rs7668531 chr4:90791819 G/T cg14346243 chr4:90757452 SNCA -0.5 -4.75 -0.39 5.44e-6 Dementia with Lewy bodies; TGCT cis rs17345786 0.798 rs4257518 chr3:101281709 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.63 -6.03 -0.48 1.71e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.683 rs6588440 chr1:53209587 C/T cg22166914 chr1:53195759 ZYG11B -0.5 -9.17 -0.64 1.29e-15 Monocyte count; TGCT cis rs2242116 0.896 rs724449 chr3:46935681 C/T cg02527881 chr3:46936655 PTH1R -0.29 -5.66 -0.45 1.02e-7 Birth weight; TGCT cis rs2361718 0.631 rs12601637 chr17:78142455 T/C cg09238746 chr17:78121135 EIF4A3 -0.77 -7.39 -0.55 1.88e-11 Yeast infection; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs4851254 0.660 rs34714421 chr2:100692175 T/C cg07810366 chr2:100720526 AFF3 -0.49 -5.15 -0.42 1e-6 Intelligence (multi-trait analysis); TGCT cis rs2948294 0.588 rs12544596 chr8:8116346 A/T cg15462221 chr8:8086144 FLJ10661 -0.59 -5.0 -0.41 1.94e-6 Red cell distribution width; TGCT cis rs7178572 0.524 rs11853287 chr15:77399371 A/G cg15453836 chr15:77711506 NA -0.4 -4.54 -0.38 1.31e-5 Type 2 diabetes; TGCT trans rs3780486 0.846 rs3824458 chr9:33144809 C/T cg20290983 chr6:43655470 MRPS18A 1.17 14.36 0.79 3.87e-28 IgG glycosylation; TGCT cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg20637647 chr7:64974828 NA -1.0 -5.59 -0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs801193 0.569 rs11772819 chr7:66217970 T/C cg11764359 chr7:65958608 NA 0.52 4.6 0.38 1.04e-5 Aortic root size; TGCT cis rs11651000 0.857 rs11658383 chr17:45842354 A/C cg06532163 chr17:45867833 NA 0.36 5.24 0.43 6.81e-7 IgG glycosylation; TGCT cis rs514406 0.861 rs1571979 chr1:53237526 G/A cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg25151919 chr3:44754333 ZNF502 -0.43 -4.98 -0.41 2.05e-6 Depressive symptoms; TGCT cis rs853679 0.517 rs17774663 chr6:28120898 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs2721195 0.967 rs11777703 chr8:145703508 G/A cg11211951 chr8:145729740 GPT -0.23 -5.41 -0.44 3.17e-7 Age at first birth; TGCT cis rs2688608 0.967 rs1815076 chr10:75659886 C/T cg23231163 chr10:75533350 FUT11 -0.27 -4.82 -0.4 4.04e-6 Inflammatory bowel disease; TGCT cis rs7647973 0.626 rs6809879 chr3:49834571 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.75 -0.39 5.61e-6 Menarche (age at onset); TGCT cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.8 9.07 0.63 2.27e-15 Menarche (age at onset); TGCT cis rs523522 0.962 rs4767904 chr12:120930798 T/G cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs9549367 0.577 rs3024711 chr13:113813268 A/G cg00898013 chr13:113819073 PROZ -0.55 -6.6 -0.51 1.05e-9 Platelet distribution width; TGCT cis rs7666738 0.830 rs3852122 chr4:98697400 T/C cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs778371 0.915 rs938569 chr2:233759695 C/G cg08000102 chr2:233561755 GIGYF2 0.59 6.33 0.49 4.09e-9 Schizophrenia; TGCT cis rs7923609 0.967 rs7920058 chr10:65293924 T/G cg08743896 chr10:65200160 JMJD1C -0.33 -4.48 -0.37 1.71e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs6582630 0.502 rs4559747 chr12:38436235 G/A cg13010199 chr12:38710504 ALG10B 0.55 4.46 0.37 1.84e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs4733781 1.000 rs72722365 chr8:131190914 G/A cg16277922 chr8:131349729 ASAP1 0.44 5.64 0.45 1.11e-7 Tuberculosis; TGCT cis rs3821902 0.502 rs17031765 chr3:64036167 A/G cg22134162 chr3:63841271 THOC7 -0.33 -4.46 -0.37 1.82e-5 Breast cancer; TGCT cis rs9952991 0.883 rs2847260 chr18:12775591 C/T cg23598886 chr18:12777645 NA 0.62 5.78 0.46 5.63e-8 Inflammatory skin disease; TGCT trans rs7819412 0.618 rs34772085 chr8:10964906 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -7.08 -0.54 9.64e-11 Triglycerides; TGCT trans rs9650657 0.537 rs11250092 chr8:10786543 A/G cg15556689 chr8:8085844 FLJ10661 0.75 6.67 0.51 7.63e-10 Neuroticism; TGCT cis rs6750047 0.546 rs1367696 chr2:38286914 C/T cg07380506 chr2:38303506 CYP1B1 0.68 6.34 0.49 3.89e-9 Cutaneous malignant melanoma;Melanoma; TGCT cis rs56334439 0.831 rs67221972 chr3:60100560 T/C cg17894779 chr3:60066405 FHIT -0.35 -4.81 -0.4 4.3e-6 Myringotomy; TGCT cis rs28735056 0.904 rs62103183 chr18:77626564 A/G cg20368463 chr18:77673604 PQLC1 0.4 4.89 0.4 3.09e-6 Schizophrenia; TGCT cis rs10504229 0.679 rs16921623 chr8:58039473 G/C cg08280861 chr8:58055591 NA 0.35 4.94 0.41 2.49e-6 Developmental language disorder (linguistic errors); TGCT cis rs1577917 0.958 rs11755864 chr6:86691791 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.48 -0.44 2.23e-7 Response to antipsychotic treatment; TGCT cis rs2204008 0.614 rs4578492 chr12:38036350 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.63 0.57 5.5e-12 Bladder cancer; TGCT cis rs7618915 0.571 rs6798246 chr3:52599922 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs4285028 0.699 rs12637968 chr3:121599976 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.78 -6.72 -0.52 5.95e-10 Multiple sclerosis; TGCT cis rs6545883 0.868 rs28749199 chr2:61827052 A/G cg15711740 chr2:61764176 XPO1 -0.6 -5.67 -0.45 9.56e-8 Tuberculosis; TGCT cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg03264133 chr6:25882463 NA -0.57 -6.07 -0.48 1.45e-8 Blood metabolite levels; TGCT cis rs1371867 0.817 rs1788185 chr8:101335529 T/C cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs6952809 0.590 rs1468337 chr7:2432211 C/T cg23289794 chr7:2394357 EIF3B -0.83 -7.09 -0.54 8.92e-11 Multiple sclerosis; TGCT cis rs67478160 0.584 rs12433009 chr14:104196405 C/G cg26031613 chr14:104095156 KLC1 -0.77 -7.67 -0.57 4.27e-12 Schizophrenia; TGCT cis rs7833790 1.000 rs7460277 chr8:82709777 T/C cg17211192 chr8:82754475 SNX16 -1.05 -8.4 -0.6 8.8e-14 Diastolic blood pressure; TGCT cis rs6570726 0.791 rs398408 chr6:145801020 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.83 0.66 3.33e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg11301795 chr4:187892539 NA -0.35 -5.28 -0.43 5.6e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs35306767 0.714 rs66797613 chr10:1090469 C/T cg26597838 chr10:835615 NA 0.61 7.09 0.54 8.8e-11 Eosinophil percentage of granulocytes; TGCT cis rs2637266 0.739 rs2579737 chr10:78422546 G/T cg18941641 chr10:78392320 NA 0.38 4.57 0.38 1.15e-5 Pulmonary function; TGCT cis rs6964587 0.869 rs2023784 chr7:91524677 A/G cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs7599312 0.534 rs2371615 chr2:213405660 G/T cg20637307 chr2:213403960 ERBB4 0.91 11.8 0.73 5.12e-22 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs763121 0.853 rs5757193 chr22:39034867 A/G cg06022373 chr22:39101656 GTPBP1 -0.79 -7.74 -0.57 3.07e-12 Menopause (age at onset); TGCT cis rs9810089 0.814 rs10804640 chr3:136165695 G/A cg12473912 chr3:136751656 NA 0.37 5.13 0.42 1.1e-6 Gestational age at birth (child effect); TGCT cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs12477438 0.520 rs1133978 chr2:99741964 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs8177253 1.000 rs8177271 chr3:133482230 G/A cg20276088 chr3:133502917 NA -0.24 -4.96 -0.41 2.28e-6 Iron status biomarkers; TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs9952991 0.566 rs7234029 chr18:12877060 C/T cg23598886 chr18:12777645 NA 0.55 4.92 0.4 2.71e-6 Inflammatory skin disease; TGCT cis rs68170813 0.559 rs79705824 chr7:106848325 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs57506017 0.585 rs12699338 chr7:12285140 C/T cg07541786 chr7:12610355 SCIN 0.47 4.73 0.39 6.02e-6 Neuroticism; TGCT cis rs6977660 0.714 rs12666488 chr7:19788403 G/A cg07541023 chr7:19748670 TWISTNB 0.83 4.69 0.39 7.01e-6 Thyroid stimulating hormone; TGCT cis rs56036086 0.536 rs73187263 chr22:50651785 C/T cg19890858 chr22:50624742 TRABD 1.05 5.1 0.42 1.23e-6 Platelet count;Plateletcrit; TGCT cis rs2228479 0.717 rs62052210 chr16:89980158 A/G cg19635926 chr16:89946313 TCF25 0.28 5.1 0.42 1.23e-6 Skin colour saturation; TGCT cis rs748404 0.518 rs2927085 chr15:43989530 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.59 0.38 1.07e-5 Lung cancer; TGCT cis rs826838 1.000 rs11168218 chr12:38884466 A/G cg26384229 chr12:38710491 ALG10B 1.04 10.43 0.68 1.11e-18 Heart rate; TGCT trans rs8073060 0.559 rs72829925 chr17:34049778 C/A cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6952808 0.756 rs12537348 chr7:1948172 C/G cg04267008 chr7:1944627 MAD1L1 -0.39 -5.3 -0.43 5.04e-7 Bipolar disorder and schizophrenia; TGCT cis rs6582630 0.519 rs4294627 chr12:38293982 C/T cg26384229 chr12:38710491 ALG10B 0.82 7.18 0.54 5.6e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs877282 0.947 rs7475589 chr10:767479 C/G cg17470449 chr10:769945 NA 0.34 5.12 0.42 1.15e-6 Uric acid levels; TGCT cis rs908922 0.627 rs11590073 chr1:152500810 C/T cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.26e-9 Hair morphology; TGCT cis rs7552404 0.924 rs2173378 chr1:76201992 G/T cg10523679 chr1:76189770 ACADM 0.84 9.32 0.64 5.67e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs360798 0.532 rs12713468 chr2:62983213 G/A cg17519650 chr2:63277830 OTX1 -0.58 -5.06 -0.41 1.48e-6 Coronary artery disease; TGCT cis rs2760061 0.819 rs3094914 chr1:228206934 C/T cg18477163 chr1:228402036 OBSCN 0.34 7.24 0.55 4.1e-11 Diastolic blood pressure; TGCT cis rs11252926 0.624 rs7085214 chr10:468133 A/G cg20256804 chr10:444983 DIP2C -0.22 -5.1 -0.42 1.22e-6 Psychosis in Alzheimer's disease; TGCT cis rs73001065 0.818 rs12610185 chr19:19721722 G/A cg03709012 chr19:19516395 GATAD2A 1.04 5.1 0.42 1.26e-6 LDL cholesterol; TGCT cis rs78366141 0.536 rs76806573 chr4:89682729 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.17 5.22 0.42 7.28e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs9325144 0.600 rs12297194 chr12:38735803 A/G cg26384229 chr12:38710491 ALG10B -0.61 -5.81 -0.46 5.03e-8 Morning vs. evening chronotype; TGCT cis rs1156327 0.826 rs4617844 chr16:19325091 A/G cg02978544 chr16:19716338 NA -0.42 -4.46 -0.37 1.82e-5 Periodontal disease-related phenotypes; TGCT cis rs2346177 0.580 rs1530628 chr2:46670941 A/G cg26688816 chr2:46740690 ATP6V1E2 -0.45 -5.06 -0.41 1.45e-6 HDL cholesterol; TGCT cis rs11098499 0.863 rs6858777 chr4:120475966 A/G cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs7666738 0.800 rs1559858 chr4:99024075 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.06 0.41 1.48e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7659604 0.605 rs2071486 chr4:122740162 C/T cg06713675 chr4:122721982 EXOSC9 -0.63 -8.74 -0.62 1.39e-14 Type 2 diabetes; TGCT cis rs7833790 0.724 rs6473311 chr8:82726682 G/A cg06027949 chr8:82754900 SNX16 -0.65 -5.03 -0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs8028182 0.636 rs28783769 chr15:75849009 C/A cg20655648 chr15:75932815 IMP3 0.58 4.61 0.38 1e-5 Sudden cardiac arrest; TGCT cis rs2456568 0.570 rs1518579 chr11:93656821 A/G cg16099599 chr11:93583650 C11orf90 -0.41 -4.83 -0.4 4.02e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9467773 1.000 rs1078679 chr6:26568741 C/T cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.586 rs10267212 chr7:99595422 T/C cg13334819 chr7:99746414 C7orf59 -0.74 -6.4 -0.5 2.92e-9 Coronary artery disease; TGCT cis rs3125734 0.534 rs10821973 chr10:64052337 G/A cg09941381 chr10:64027924 RTKN2 -0.33 -4.9 -0.4 2.94e-6 Rheumatoid arthritis; TGCT cis rs2073300 1.000 rs6048834 chr20:23462213 C/T cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs13242816 1.000 rs62471184 chr7:116090300 G/A cg02799643 chr7:116139180 CAV2 -0.44 -5.22 -0.42 7.16e-7 P wave duration; TGCT cis rs854765 0.693 rs4924823 chr17:17764502 A/G cg04398451 chr17:18023971 MYO15A 0.29 4.57 0.38 1.15e-5 Total body bone mineral density; TGCT cis rs2016266 0.855 rs1379610 chr12:53681683 A/G cg16917193 chr12:54089295 NA -0.67 -4.94 -0.41 2.52e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs9527 0.640 rs35195396 chr10:104928770 T/A cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.07e-7 Arsenic metabolism; TGCT cis rs1008375 0.966 rs1860599 chr4:17638900 T/C cg18681998 chr4:17616180 MED28 1.01 11.55 0.72 2.15e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 1.000 rs6037095 chr20:25335687 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg17747265 chr1:1875780 NA 0.37 6.51 0.5 1.71e-9 Body mass index; TGCT cis rs6840360 1.000 rs6810860 chr4:152603164 C/T cg17479576 chr4:152424074 FAM160A1 0.49 5.17 0.42 9.2e-7 Intelligence (multi-trait analysis); TGCT cis rs4319547 0.695 rs11057797 chr12:122860732 G/A cg05707623 chr12:122985044 ZCCHC8 0.62 4.87 0.4 3.32e-6 Body mass index; TGCT cis rs2235642 0.717 rs2236269 chr16:1652614 T/A cg08296037 chr16:1584118 IFT140;TMEM204 -0.29 -5.03 -0.41 1.68e-6 Coronary artery disease; TGCT cis rs7617773 0.743 rs7621785 chr3:48343708 T/C cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs7208859 0.673 rs73277986 chr17:29196197 C/T cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4689388 0.889 rs13128674 chr4:6294517 C/T cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs709400 0.663 rs7145113 chr14:103945414 A/G cg12935359 chr14:103987150 CKB -0.36 -5.56 -0.45 1.61e-7 Body mass index; TGCT cis rs589448 0.538 rs622656 chr12:69753595 C/T cg19645103 chr12:69753606 YEATS4 -0.62 -5.14 -0.42 1.04e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs225245 0.817 rs225273 chr17:33970935 A/T cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.53e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs11190604 1.000 rs2295773 chr10:102265815 A/G cg23241863 chr10:102295624 HIF1AN 0.67 5.13 0.42 1.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT trans rs7618501 1.000 rs7374183 chr3:49785133 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.529 rs58757492 chr20:30181425 G/A cg13852791 chr20:30311386 BCL2L1 0.69 4.53 0.38 1.36e-5 Mean corpuscular hemoglobin; TGCT cis rs16866061 1.000 rs72974203 chr2:225408430 G/A cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs6752107 0.967 rs56227616 chr2:234157741 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 5.0 0.41 1.87e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7666738 0.822 rs13110418 chr4:99046963 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7714584 1.000 rs11167526 chr5:150332481 G/A cg22134413 chr5:150180641 NA 1.0 4.79 0.4 4.64e-6 Crohn's disease; TGCT cis rs73198271 0.773 rs66618176 chr8:8646974 G/C cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9902453 0.726 rs3110494 chr17:27976597 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.86 8.52 0.61 4.53e-14 Coffee consumption (cups per day); TGCT cis rs11096990 0.634 rs1057807 chr4:39289473 A/G cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs2486012 0.850 rs2906462 chr1:44332084 G/A cg12908607 chr1:44402522 ARTN -0.69 -5.57 -0.45 1.49e-7 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.677 rs11130211 chr3:49645209 C/T cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs208520 0.802 rs4710315 chr6:66887594 A/G cg07460842 chr6:66804631 NA -0.9 -9.36 -0.64 4.37e-16 Exhaled nitric oxide output; TGCT cis rs7772486 0.701 rs697056 chr6:146003897 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs422249 0.896 rs174449 chr11:61640379 A/G cg19610905 chr11:61596333 FADS2 -0.6 -5.25 -0.43 6.45e-7 Trans fatty acid levels; TGCT cis rs7843479 0.601 rs10866837 chr8:21861663 G/C cg17168535 chr8:21777572 XPO7 0.8 8.16 0.59 3.19e-13 Mean corpuscular volume; TGCT cis rs9926296 0.546 rs6500442 chr16:89828862 T/C cg27121462 chr16:89883253 FANCA 0.78 8.53 0.61 4.29e-14 Vitiligo; TGCT cis rs2288073 1.000 rs2288073 chr2:24413298 C/T cg05570707 chr2:24270316 C2orf44 0.52 4.63 0.38 9.16e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs3749237 0.595 rs1464566 chr3:49459376 T/C cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs9910055 0.529 rs228748 chr17:42174390 G/A cg19774624 chr17:42201019 HDAC5 0.7 6.71 0.52 6.31e-10 Total body bone mineral density; TGCT cis rs1552244 0.572 rs6442154 chr3:10168785 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs4409675 0.576 rs12070659 chr1:28227175 G/A cg23691781 chr1:28212827 C1orf38 0.25 5.38 0.43 3.59e-7 Corneal astigmatism; TGCT cis rs10504229 0.679 rs10504217 chr8:58037522 A/G cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs10193935 1.000 rs13411405 chr2:42413811 C/A cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs933688 0.532 rs28637141 chr5:90538743 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.54 -4.82 -0.4 4.09e-6 Smoking behavior; TGCT cis rs17473412 0.895 rs58039148 chr5:122746941 C/A cg15125798 chr5:122621645 NA -0.55 -5.03 -0.41 1.69e-6 Total body bone mineral density; TGCT cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg06238570 chr21:40685208 BRWD1 -0.61 -6.34 -0.49 3.83e-9 Menarche (age at onset); TGCT cis rs4886920 0.563 rs12915515 chr15:78075555 A/T cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs9549367 0.713 rs3024743 chr13:113821430 C/T cg18105134 chr13:113819100 PROZ -0.47 -8.19 -0.59 2.73e-13 Platelet distribution width; TGCT cis rs7193541 0.585 rs7978 chr16:74486189 T/C cg01733217 chr16:74700730 RFWD3 -0.82 -9.42 -0.65 3.25e-16 Multiple myeloma; TGCT cis rs26868 0.742 rs26848 chr16:2263516 A/G cg07105046 chr16:2261082 C16orf79 -0.28 -4.77 -0.39 5.06e-6 Height; TGCT cis rs6121246 0.529 rs6060174 chr20:30183538 G/A cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs6121246 0.567 rs2889488 chr20:30185758 G/A cg18721089 chr20:30220636 NA -0.57 -6.22 -0.49 6.83e-9 Mean corpuscular hemoglobin; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg01802117 chr1:53393560 SCP2 -0.39 -4.55 -0.38 1.27e-5 Monocyte count; TGCT cis rs7714584 1.000 rs10052606 chr5:150272217 T/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs929354 0.557 rs62491947 chr7:156960813 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs7681440 0.804 rs1442140 chr4:90816023 A/G cg14346243 chr4:90757452 SNCA -0.5 -4.93 -0.4 2.61e-6 Dementia with Lewy bodies; TGCT cis rs13326165 0.585 rs35860312 chr3:52387078 T/C cg07884673 chr3:53033167 SFMBT1 0.4 4.86 0.4 3.45e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7188861 0.626 rs7193871 chr16:11455606 C/G cg00044050 chr16:11439710 C16orf75 0.69 6.55 0.51 1.39e-9 HDL cholesterol; TGCT cis rs1865760 0.532 rs2006736 chr6:26086017 C/T cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs9914988 0.887 rs8078402 chr17:27145124 T/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2075165 0.901 rs2025577 chr1:156314104 T/C cg16558208 chr1:156270281 VHLL 0.27 4.85 0.4 3.68e-6 Tonsillectomy; TGCT cis rs1008375 0.931 rs6449328 chr4:17700474 C/T cg18681998 chr4:17616180 MED28 0.78 7.37 0.55 2.06e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs611744 0.647 rs7015513 chr8:109262570 A/C cg21045802 chr8:109455806 TTC35 0.69 6.92 0.53 2.12e-10 Dupuytren's disease; TGCT cis rs9796 0.870 rs2412572 chr15:41264426 G/C cg18705301 chr15:41695430 NDUFAF1 0.43 5.59 0.45 1.39e-7 Menopause (age at onset); TGCT cis rs3803170 0.513 rs10849941 chr12:111818487 A/T cg10833066 chr12:111807467 FAM109A 0.35 5.4 0.44 3.26e-7 Mean corpuscular hemoglobin; TGCT cis rs13242816 1.000 rs73206052 chr7:116117056 G/T cg16553024 chr7:116138462 CAV2 -0.56 -5.54 -0.45 1.74e-7 P wave duration; TGCT trans rs57221529 0.766 rs17563576 chr5:560476 A/G cg25482853 chr8:67687455 SGK3 1.25 10.34 0.68 1.86e-18 Lung disease severity in cystic fibrosis; TGCT cis rs3892630 0.878 rs11878394 chr19:33205844 G/C cg22980127 chr19:33182716 NUDT19 0.71 5.22 0.42 7.46e-7 Red blood cell traits; TGCT cis rs1862618 0.620 rs189695 chr5:56225769 T/C cg12311346 chr5:56204834 C5orf35 -0.57 -6.13 -0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs9436747 0.641 rs4655680 chr1:66041469 G/T cg14976592 chr1:65886160 LEPROT;LEPR 0.54 5.11 0.42 1.17e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs9467773 1.000 rs1078679 chr6:26568741 C/T cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.966 rs2424715 chr20:25420077 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs67478160 0.634 rs941473 chr14:104201869 C/G cg26031613 chr14:104095156 KLC1 -0.6 -5.97 -0.47 2.27e-8 Schizophrenia; TGCT cis rs10751667 0.961 rs6597971 chr11:928598 T/A cg06064525 chr11:970664 AP2A2 -0.31 -6.11 -0.48 1.19e-8 Alzheimer's disease (late onset); TGCT cis rs877282 0.853 rs7079299 chr10:756455 A/G cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs2033711 0.905 rs1077420 chr19:58968875 A/C cg04608855 chr19:58913158 NA 0.55 5.29 0.43 5.23e-7 Uric acid clearance; TGCT cis rs6728642 1.000 rs59178801 chr2:97604455 C/T cg26665480 chr2:98280029 ACTR1B -0.92 -5.6 -0.45 1.34e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs2439831 0.867 rs4075674 chr15:43650230 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs3091242 0.806 rs35189848 chr1:25788422 A/G cg00786635 chr1:25594202 NA -0.55 -5.67 -0.45 9.46e-8 Erythrocyte sedimentation rate; TGCT cis rs2197308 0.667 rs11181073 chr12:37898543 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.93 0.4 2.57e-6 Morning vs. evening chronotype; TGCT cis rs13202913 0.837 rs6906678 chr6:151772395 A/T cg03627880 chr6:151815985 C6orf97 -0.62 -4.64 -0.38 8.66e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs1215050 0.846 rs1839903 chr4:98791414 C/T cg17366294 chr4:99064904 C4orf37 0.48 4.83 0.4 3.94e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg16325326 chr1:53192061 ZYG11B 0.6 6.77 0.52 4.62e-10 Monocyte count; TGCT cis rs1218582 0.741 rs11264291 chr1:154914797 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.67 -6.88 -0.53 2.57e-10 Prostate cancer; TGCT cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs1577917 1.000 rs12190598 chr6:86686074 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.41 -0.44 3.05e-7 Response to antipsychotic treatment; TGCT cis rs7552404 0.690 rs11161620 chr1:76255228 A/G cg03433033 chr1:76189801 ACADM -0.64 -6.64 -0.51 8.75e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1218582 0.772 rs2102423 chr1:154916068 A/G cg16680214 chr1:154839983 KCNN3 -0.35 -7.15 -0.54 6.42e-11 Prostate cancer; TGCT cis rs1218582 0.740 rs1977879 chr1:154879743 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs250677 0.687 rs384979 chr5:148459267 C/T cg23229984 chr5:148520753 ABLIM3 -0.2 -4.57 -0.38 1.14e-5 Breast cancer; TGCT cis rs28595532 0.920 rs17324884 chr4:119771477 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs2692947 0.644 rs3821051 chr2:96912787 A/G cg23100626 chr2:96804247 ASTL -0.45 -5.86 -0.47 3.84e-8 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs11105298 0.891 rs4842664 chr12:89938030 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.75 -5.31 -0.43 4.89e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs3008870 0.755 rs12562761 chr1:67396739 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.79 8.42 0.6 7.66e-14 Lymphocyte percentage of white cells; TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.05 0.53 1.1e-10 Prudent dietary pattern; TGCT cis rs6964587 0.692 rs4727268 chr7:91840724 T/C cg17063962 chr7:91808500 NA 0.77 7.17 0.54 6.08e-11 Breast cancer; TGCT cis rs1018836 0.828 rs2105968 chr8:91591825 A/G cg16814680 chr8:91681699 NA -0.69 -6.84 -0.52 3.21e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6700896 0.500 rs7540268 chr1:66085236 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7412746 0.611 rs10888398 chr1:150886782 A/G cg09365446 chr1:150670422 GOLPH3L -0.34 -4.71 -0.39 6.58e-6 Melanoma; TGCT cis rs4750440 0.576 rs2447011 chr10:14032199 C/T cg05755354 chr10:14372596 FRMD4A 0.3 4.77 0.39 5.1e-6 Adiponectin levels; TGCT cis rs28374715 0.662 rs522063 chr15:41476209 A/G cg18705301 chr15:41695430 NDUFAF1 0.72 10.65 0.69 3.35e-19 Ulcerative colitis; TGCT cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs9322193 0.923 rs9322208 chr6:149979683 A/T cg13206674 chr6:150067644 NUP43 0.51 4.47 0.37 1.75e-5 Lung cancer; TGCT cis rs74233809 1.000 rs78260931 chr10:104721962 G/C cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs11673344 0.523 rs7246739 chr19:37531731 G/C cg08039142 chr19:36980659 ZNF566 0.5 4.64 0.38 8.58e-6 Obesity-related traits; TGCT cis rs9303401 0.614 rs2333409 chr17:57139134 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.82 0.46 4.8e-8 Cognitive test performance; TGCT cis rs7772486 0.790 rs3924499 chr6:146232978 A/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.55e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 1.000 rs11759855 chr6:86610841 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs4722166 0.630 rs7808457 chr7:22798265 A/T cg23864514 chr7:22882512 NA -0.21 -4.47 -0.37 1.76e-5 Lung cancer; TGCT cis rs7584330 0.554 rs880931 chr2:238396741 G/A cg14458575 chr2:238380390 NA 0.58 5.05 0.41 1.53e-6 Prostate cancer; TGCT cis rs12681287 0.547 rs4961197 chr8:87512436 T/C cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs62380364 0.565 rs40504 chr5:88011139 G/C cg24804195 chr5:87968844 LOC645323 -0.61 -6.09 -0.48 1.31e-8 Intelligence (multi-trait analysis); TGCT cis rs10465746 0.746 rs6663949 chr1:84452853 T/C cg10977910 chr1:84465055 TTLL7 0.67 6.69 0.52 6.72e-10 Obesity-related traits; TGCT cis rs7810240 1.000 rs4725889 chr7:150092684 A/G cg24650120 chr7:150096722 NA -0.71 -9.66 -0.66 8.6e-17 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs1448094 0.654 rs7133797 chr12:86294184 G/C cg02569458 chr12:86230093 RASSF9 0.35 4.53 0.38 1.38e-5 Major depressive disorder; TGCT cis rs3806843 0.966 rs2563263 chr5:140137644 A/G cg19875535 chr5:140030758 IK 0.36 5.96 0.47 2.48e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7267979 1.000 rs4815424 chr20:25390284 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6089584 0.566 rs6061963 chr20:60607480 C/G cg06108461 chr20:60628389 TAF4 -0.45 -5.65 -0.45 1.04e-7 Body mass index; TGCT cis rs3125734 0.633 rs10761616 chr10:64009076 G/A cg05499367 chr10:63213510 TMEM26 -0.33 -4.44 -0.37 1.96e-5 Rheumatoid arthritis; TGCT cis rs1050631 0.960 rs1789516 chr18:33691688 T/A cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.98 0.41 2.07e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs508618 0.731 rs12033229 chr1:231545703 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.6 4.92 0.4 2.64e-6 Red blood cell count; TGCT cis rs11673344 0.542 rs826327 chr19:37495299 A/G cg08039142 chr19:36980659 ZNF566 0.52 4.85 0.4 3.69e-6 Obesity-related traits; TGCT cis rs9894429 0.789 rs7502346 chr17:79603741 T/C cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT trans rs2727020 0.857 rs1917324 chr11:49371759 G/C cg03929089 chr4:120376271 NA -0.67 -6.99 -0.53 1.52e-10 Coronary artery disease; TGCT cis rs60843830 1.000 rs7595075 chr2:264019 C/A cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.69 0.57 3.87e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9787249 0.957 rs10888958 chr1:40211737 T/C cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs9611565 0.546 rs739132 chr22:42123099 A/T cg13695892 chr22:41940480 POLR3H 0.88 8.63 0.61 2.45e-14 Vitiligo; TGCT cis rs34638657 0.732 rs11645372 chr16:82202136 C/T cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs950169 0.887 rs12903946 chr15:84954430 T/C cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs7833790 0.654 rs6415652 chr8:82702257 G/A cg17211192 chr8:82754475 SNX16 -0.88 -7.68 -0.57 4.16e-12 Diastolic blood pressure; TGCT cis rs7226408 0.842 rs11660045 chr18:34381159 C/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs9611565 0.592 rs6519270 chr22:42078666 A/G cg06634786 chr22:41940651 POLR3H 0.84 8.08 0.59 4.86e-13 Vitiligo; TGCT cis rs1865760 0.588 rs9467658 chr6:26010881 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.76 7.21 0.54 4.86e-11 Height; TGCT cis rs78456975 0.550 rs10197874 chr2:1545310 A/G cg12573674 chr2:1569213 NA -0.47 -4.72 -0.39 6.26e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs4563143 0.514 rs73029081 chr19:29295583 C/G cg12756686 chr19:29218302 NA 0.67 5.16 0.42 9.34e-7 Methadone dose in opioid dependence; TGCT cis rs4906332 1.000 rs34347076 chr14:103955069 G/A cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs7582180 0.715 rs764828 chr2:100908634 A/C cg08017756 chr2:100939284 LONRF2 -0.28 -4.56 -0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs2688608 0.592 rs10824031 chr10:75509273 C/T cg15838173 chr10:75533400 FUT11 -0.3 -5.02 -0.41 1.76e-6 Inflammatory bowel disease; TGCT trans rs877282 0.842 rs35117541 chr10:764683 C/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs9330316 0.632 rs2043462 chr2:110364811 C/T cg25199208 chr2:109402912 CCDC138 -0.41 -4.44 -0.37 1.99e-5 Schizophrenia; TGCT cis rs9787249 0.957 rs10888958 chr1:40211737 T/C cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs67311347 1.000 rs2276868 chr3:40498845 C/T cg13683864 chr3:40499215 RPL14 1.03 10.28 0.68 2.62e-18 Renal cell carcinoma; TGCT cis rs7954584 0.520 rs1169096 chr12:122465836 G/C cg22168489 chr12:122356033 WDR66 -0.19 -4.52 -0.38 1.42e-5 Mean corpuscular volume; TGCT cis rs78487399 0.908 rs6731636 chr2:43843046 G/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.53 0.38 1.39e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3099143 1.000 rs2629034 chr15:77042240 G/A cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Recalcitrant atopic dermatitis; TGCT cis rs3015497 0.789 rs3015502 chr14:51108427 T/C cg04730355 chr14:51134070 SAV1 -0.65 -6.29 -0.49 5.07e-9 Mean platelet volume; TGCT cis rs62103177 0.525 rs4283293 chr18:77759582 A/G cg20368463 chr18:77673604 PQLC1 -0.43 -4.46 -0.37 1.83e-5 Opioid sensitivity; TGCT cis rs6750795 0.569 rs1667305 chr2:232403829 A/G cg19187155 chr2:232395269 NMUR1 0.41 4.72 0.39 6.29e-6 Height; TGCT cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg26531700 chr6:26746687 NA 0.52 5.01 0.41 1.8e-6 Intelligence (multi-trait analysis); TGCT cis rs67385638 1.000 rs72872548 chr11:5289139 C/A cg12559170 chr11:5275217 HBG2 0.47 8.38 0.6 9.96e-14 Hemoglobin levels; TGCT cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Intelligence (multi-trait analysis); TGCT cis rs826838 0.967 rs1719852 chr12:39128531 A/G cg26384229 chr12:38710491 ALG10B -0.83 -7.31 -0.55 2.88e-11 Heart rate; TGCT cis rs11122272 0.735 rs2437150 chr1:231488524 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.73 6.95 0.53 1.83e-10 Hemoglobin concentration; TGCT cis rs11190604 0.767 rs10883491 chr10:102196071 G/T cg16342193 chr10:102329863 NA -0.41 -5.22 -0.42 7.22e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7945705 0.869 rs11042154 chr11:9029700 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -5.19 -0.42 8.41e-7 Hemoglobin concentration; TGCT cis rs9733 0.596 rs72702556 chr1:150680115 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs4449834 0.961 rs4738832 chr8:61760521 A/G cg12485212 chr8:61565947 NA -0.61 -4.5 -0.37 1.53e-5 Sum eosinophil basophil counts; TGCT cis rs6952808 0.608 rs6461049 chr7:2017445 C/T cg04267008 chr7:1944627 MAD1L1 0.34 4.62 0.38 9.66e-6 Bipolar disorder and schizophrenia; TGCT cis rs922182 0.663 rs7180057 chr15:64263795 G/A cg02919090 chr15:64263738 DAPK2 0.38 7.06 0.54 1.03e-10 Blood protein levels; TGCT cis rs2439831 0.850 rs3759790 chr15:44121030 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT trans rs2970818 0.831 rs7304949 chr12:4609625 A/G cg23273947 chr15:68267131 NA 0.28 7.64 0.57 5.02e-12 Phosphorus levels; TGCT cis rs7824557 0.767 rs6991606 chr8:11176159 G/A cg21775007 chr8:11205619 TDH 0.54 5.21 0.42 7.76e-7 Retinal vascular caliber; TGCT cis rs36051895 0.575 rs7035251 chr9:5133665 T/A cg02405213 chr9:5042618 JAK2 -0.75 -10.52 -0.69 6.97e-19 Pediatric autoimmune diseases; TGCT cis rs1018836 0.923 rs7013893 chr8:91563137 G/A cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs6088580 0.634 rs6120669 chr20:33105028 T/C cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs7727544 0.660 rs272886 chr5:131665840 T/C cg24060327 chr5:131705240 SLC22A5 -0.57 -6.43 -0.5 2.53e-9 Blood metabolite levels; TGCT cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg06212747 chr3:49208901 KLHDC8B 0.66 6.35 0.5 3.77e-9 Menarche (age at onset); TGCT trans rs1814175 0.817 rs7946556 chr11:49944874 G/A cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs8031584 0.918 rs1425292 chr15:31285422 G/A cg08704250 chr15:31115839 NA -0.36 -4.93 -0.4 2.59e-6 Huntington's disease progression; TGCT cis rs7666738 0.830 rs13115356 chr4:98933171 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12791968 1.000 rs1552300 chr11:45002594 G/A cg11846598 chr11:44996168 LOC221122 -0.36 -6.79 -0.52 4.04e-10 Inhibitory control; TGCT cis rs4746818 1.000 rs7918066 chr10:70913116 C/T cg04149295 chr10:70884716 VPS26A 0.79 5.44 0.44 2.79e-7 Left atrial antero-posterior diameter; TGCT cis rs7666738 0.830 rs11726604 chr4:99000969 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7731657 0.509 rs6595984 chr5:130335884 A/G cg08523029 chr5:130500466 HINT1 0.57 4.73 0.39 5.93e-6 Fasting plasma glucose; TGCT cis rs904251 0.965 rs1317563 chr6:37451854 G/T cg01843034 chr6:37503916 NA -0.42 -4.86 -0.4 3.45e-6 Cognitive performance; TGCT cis rs1385374 0.858 rs11059928 chr12:129296103 A/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs295137 0.836 rs1217456 chr2:201092279 C/T cg17644776 chr2:200775616 C2orf69 0.23 4.53 0.38 1.38e-5 Asthma (bronchodilator response); TGCT cis rs6424115 0.733 rs2502996 chr1:24199041 T/C cg15997130 chr1:24165203 NA 0.85 9.26 0.64 7.92e-16 Immature fraction of reticulocytes; TGCT cis rs1008375 1.000 rs3815413 chr4:17654648 T/C cg16339924 chr4:17578868 LAP3 0.67 5.55 0.45 1.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2233152 0.656 rs2287691 chr19:41286163 C/G cg23743927 chr19:41304969 EGLN2 -0.7 -4.69 -0.39 7.06e-6 Kawasaki disease; TGCT cis rs6952808 0.893 rs35487994 chr7:1920171 G/A cg04267008 chr7:1944627 MAD1L1 -0.36 -4.84 -0.4 3.83e-6 Bipolar disorder and schizophrenia; TGCT cis rs1129187 0.755 rs2296804 chr6:42931261 C/G cg17345569 chr6:42928274 GNMT -0.49 -5.05 -0.41 1.55e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2762353 0.904 rs13197514 chr6:25785991 C/T cg03517284 chr6:25882590 NA 0.51 5.33 0.43 4.47e-7 Blood metabolite levels; TGCT cis rs59197085 0.636 rs62479620 chr7:128463971 C/T cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs9611565 0.512 rs5758465 chr22:42175314 T/C cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs28595532 0.800 rs114321375 chr4:119341663 G/A cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT trans rs4332037 0.906 rs62442903 chr7:1953416 G/A cg10840412 chr1:235813424 GNG4 1.01 8.11 0.59 4.2e-13 Bipolar disorder; TGCT cis rs2180341 0.782 rs6912006 chr6:127722631 C/T cg27446573 chr6:127587934 RNF146 0.75 7.02 0.53 1.3e-10 Breast cancer; TGCT cis rs2952156 0.920 rs2934951 chr17:37833328 A/G cg20243544 chr17:37824526 PNMT 0.56 4.81 0.4 4.25e-6 Asthma; TGCT cis rs10875595 0.836 rs3749780 chr5:140682757 C/T cg20560182 chr5:140700478 TAF7 -0.63 -4.73 -0.39 5.92e-6 Pulmonary function decline; TGCT cis rs8180040 0.966 rs11710322 chr3:47331136 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.45 -0.6 6.65e-14 Colorectal cancer; TGCT cis rs1005277 0.579 rs1780145 chr10:38537070 A/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.36 -0.6 1.05e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4466137 0.553 rs16898 chr5:82986149 T/C cg16102102 chr5:83017553 HAPLN1 -0.71 -8.11 -0.59 4.1e-13 Prostate cancer; TGCT cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg03188948 chr7:1209495 NA 0.68 5.69 0.45 8.84e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6570726 0.577 rs867056 chr6:145784805 A/C cg05347473 chr6:146136440 FBXO30 -0.67 -6.34 -0.49 3.85e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6988636 0.901 rs62521825 chr8:124185786 C/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs62380364 0.566 rs1705565 chr5:88048457 C/T cg22951263 chr5:87985283 NA -0.58 -6.12 -0.48 1.12e-8 Intelligence (multi-trait analysis); TGCT cis rs7428 0.527 rs6547612 chr2:85551184 C/T cg03728395 chr2:85555865 TGOLN2 -0.3 -5.0 -0.41 1.89e-6 Ear protrusion; TGCT cis rs7829975 0.582 rs6983150 chr8:8792426 A/G cg15556689 chr8:8085844 FLJ10661 -0.67 -6.1 -0.48 1.26e-8 Mood instability; TGCT cis rs9291683 0.595 rs13145442 chr4:10037261 C/A cg11266682 chr4:10021025 SLC2A9 0.64 8.91 0.62 5.31e-15 Bone mineral density; TGCT cis rs981844 1.000 rs2606337 chr4:154656845 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs597539 0.616 rs473997 chr11:68639481 C/T cg06112835 chr11:68658793 MRPL21 0.47 8.18 0.59 2.86e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs8072100 0.701 rs2013383 chr17:45791123 T/G cg08085267 chr17:45401833 C17orf57 -0.42 -4.74 -0.39 5.78e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg16680214 chr1:154839983 KCNN3 0.3 5.54 0.45 1.75e-7 Schizophrenia; TGCT cis rs12134245 0.776 rs12122066 chr1:92005140 C/T cg07090678 chr1:91966139 CDC7 0.35 4.87 0.4 3.28e-6 Breast cancer; TGCT cis rs2301573 0.915 rs2285373 chr3:129308209 G/A cg07730360 chr3:128845626 NA 0.33 4.61 0.38 9.84e-6 Hip circumference; TGCT cis rs6087771 0.642 rs6060411 chr20:30222139 T/C cg21427119 chr20:30132790 HM13 -0.3 -5.05 -0.41 1.53e-6 Subcortical brain region volumes;Putamen volume; TGCT cis rs35306767 0.623 rs72760941 chr10:1141244 A/G cg26597838 chr10:835615 NA 0.47 4.95 0.41 2.37e-6 Eosinophil percentage of granulocytes; TGCT cis rs539096 0.872 rs10890261 chr1:44052377 G/T cg12908607 chr1:44402522 ARTN 0.52 5.43 0.44 2.8e-7 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.598 rs11182207 chr12:38477514 T/C cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs57221529 0.766 rs56278696 chr5:582669 A/G cg09021430 chr5:549028 NA -0.37 -4.98 -0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs2153535 0.580 rs2152347 chr6:8474281 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs644799 1.000 rs10831431 chr11:95510089 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.53 0.61 4.41e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2282802 0.685 rs13177186 chr5:139640476 A/G cg01081189 chr5:139537190 NA 0.29 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.713 rs7766342 chr6:25990674 C/A cg17042849 chr6:26104293 HIST1H4C -0.55 -4.8 -0.4 4.4e-6 Height; TGCT cis rs79149102 0.579 rs78664321 chr15:75339575 G/A cg09165964 chr15:75287851 SCAMP5 -1.05 -5.56 -0.45 1.59e-7 Lung cancer; TGCT cis rs3796352 1.000 rs71301814 chr3:53117663 G/A cg27565382 chr3:53032988 SFMBT1 0.44 4.71 0.39 6.52e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11190604 0.767 rs77838250 chr10:102180090 T/G cg16005271 chr10:102321736 NA 0.46 4.67 0.39 7.62e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs644799 1.000 rs509720 chr11:95562771 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6546537 0.550 rs2312202 chr2:69775104 A/C cg10773587 chr2:69614142 GFPT1 0.56 5.28 0.43 5.71e-7 Serum thyroid-stimulating hormone levels; TGCT cis rs9659323 1.000 rs11584380 chr1:119517420 C/T cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.4e-6 Body mass index; TGCT cis rs4824093 0.535 rs73441802 chr22:50273916 G/A cg14114931 chr22:50943910 LMF2 0.37 4.59 0.38 1.09e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs56104184 0.830 rs73061622 chr19:49358111 C/T cg17863274 chr19:49399704 TULP2 -0.45 -5.44 -0.44 2.69e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7804356 1.000 rs3801850 chr7:26820577 T/C cg03456212 chr7:26904342 SKAP2 -0.64 -4.88 -0.4 3.16e-6 Type 1 diabetes; TGCT cis rs1949733 0.656 rs2688224 chr4:8404700 C/G cg13073564 chr4:8508604 NA -0.43 -4.78 -0.39 4.95e-6 Response to antineoplastic agents; TGCT cis rs614226 0.935 rs588132 chr12:121024066 A/G cg01236616 chr12:121019343 POP5 1.31 13.71 0.78 1.34e-26 Type 1 diabetes nephropathy; TGCT cis rs17826219 0.636 rs8080829 chr17:29058730 C/T cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs28595532 0.920 rs114751999 chr4:119759651 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2721195 0.967 rs748195 chr8:145682514 T/C cg11211951 chr8:145729740 GPT 0.23 5.44 0.44 2.76e-7 Age at first birth; TGCT cis rs4944092 0.793 rs94111 chr11:75915139 A/G cg04588336 chr11:75916460 WNT11 -0.47 -6.76 -0.52 4.78e-10 PR interval; TGCT cis rs6061231 0.837 rs6121558 chr20:60961365 A/G cg24112000 chr20:60950667 NA -0.37 -4.92 -0.4 2.74e-6 Colorectal cancer; TGCT cis rs9902453 0.817 rs2729449 chr17:28089751 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.84 -0.52 3.22e-10 Coffee consumption (cups per day); TGCT cis rs4812048 0.793 rs6070693 chr20:57589516 C/T cg24457521 chr20:57607420 ATP5E -0.7 -4.61 -0.38 9.66e-6 Mean platelet volume; TGCT cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs9611565 0.649 rs738422 chr22:42123399 C/T cg06481639 chr22:41940642 POLR3H 0.56 4.87 0.4 3.39e-6 Vitiligo; TGCT cis rs12681287 0.640 rs13261901 chr8:87478717 G/C cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs4820539 1.000 rs4822361 chr22:23482718 A/G cg14186256 chr22:23484241 RTDR1 -0.98 -12.77 -0.75 2.31e-24 Bone mineral density; TGCT cis rs950169 0.922 rs12910334 chr15:84958318 G/A cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs7429990 0.932 rs6442101 chr3:48130893 C/T cg11946769 chr3:48343235 NME6 -0.56 -4.59 -0.38 1.07e-5 Educational attainment (years of education); TGCT cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs968451 0.547 rs11704319 chr22:39722886 A/G cg17798944 chr22:39715225 SNORD43;RPL3 -0.81 -9.21 -0.64 1.03e-15 Primary biliary cholangitis; TGCT cis rs7945705 0.747 rs2653605 chr11:8993309 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -5.01 -0.41 1.84e-6 Hemoglobin concentration; TGCT cis rs9549260 0.755 rs2755219 chr13:41169625 A/G cg21288729 chr13:41239152 FOXO1 0.99 10.12 0.67 6.41e-18 Red blood cell count; TGCT cis rs7945705 0.935 rs2568062 chr11:8887945 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -5.63 -0.45 1.13e-7 Hemoglobin concentration; TGCT cis rs6543140 0.964 rs4851593 chr2:103089227 C/T cg09003973 chr2:102972529 NA -0.55 -4.52 -0.38 1.45e-5 Blood protein levels; TGCT cis rs6088590 0.523 rs6058084 chr20:33183804 C/T cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs9467773 0.587 rs12214031 chr6:26376628 T/C cg05738196 chr6:26577821 NA -0.62 -6.56 -0.51 1.29e-9 Intelligence (multi-trait analysis); TGCT cis rs1451375 1.000 rs2329341 chr7:50620275 A/C cg18232548 chr7:50535776 DDC 0.44 6.59 0.51 1.11e-9 Malaria; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg10819733 chr22:24237672 NA -0.27 -4.47 -0.37 1.77e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6909279 0.933 rs4391273 chr6:151893073 A/C cg14416726 chr6:151773293 C6orf211;RMND1 0.53 4.47 0.37 1.77e-5 Bone mineral density; TGCT cis rs9486719 1.000 rs6921291 chr6:97066242 C/T cg06623918 chr6:96969491 KIAA0776 -1.02 -8.51 -0.61 4.91e-14 Migraine;Coronary artery disease; TGCT cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg08219700 chr8:58056026 NA 0.37 4.48 0.37 1.71e-5 Developmental language disorder (linguistic errors); TGCT cis rs6952808 0.636 rs60605830 chr7:1949198 A/G cg04267008 chr7:1944627 MAD1L1 -0.36 -4.72 -0.39 6.34e-6 Bipolar disorder and schizophrenia; TGCT cis rs860295 0.517 rs1111102 chr1:155993456 G/T cg05700447 chr1:155978627 NA -0.22 -4.93 -0.4 2.57e-6 Body mass index; TGCT cis rs7119 0.717 rs12916822 chr15:77818548 G/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.61 -0.38 9.81e-6 Type 2 diabetes; TGCT cis rs13217239 0.646 rs10946891 chr6:26973215 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 0.4 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs2404602 0.735 rs2280306 chr15:76652258 C/G cg22467129 chr15:76604101 ETFA 0.47 4.88 0.4 3.19e-6 Blood metabolite levels; TGCT cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg05985448 chr10:134359359 INPP5A 0.24 5.13 0.42 1.1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7267979 0.789 rs6083841 chr20:25384564 C/T cg13486641 chr20:25479848 NINL 0.16 4.55 0.38 1.26e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7927771 0.689 rs10734557 chr11:47380061 A/C cg21462715 chr11:47870315 NUP160 -0.55 -4.44 -0.37 1.96e-5 Subjective well-being; TGCT cis rs7590720 1.000 rs7592663 chr2:216894978 T/C cg12620499 chr2:216877984 MREG 0.87 9.2 0.64 1.11e-15 Alcohol dependence; TGCT cis rs595982 0.702 rs609985 chr19:49370648 A/G cg15549821 chr19:49342101 PLEKHA4 -0.37 -5.02 -0.41 1.74e-6 Red cell distribution width; TGCT cis rs1062177 1.000 rs6890099 chr5:151151962 A/G cg00977110 chr5:151150581 G3BP1 0.4 4.57 0.38 1.16e-5 Preschool internalizing problems; TGCT cis rs10751667 0.961 rs7482484 chr11:927020 C/T cg06064525 chr11:970664 AP2A2 -0.31 -6.11 -0.48 1.19e-8 Alzheimer's disease (late onset); TGCT cis rs617791 0.508 rs2276132 chr11:65770545 G/A cg09783858 chr11:65769428 EIF1AD;BANF1 0.49 4.49 0.37 1.64e-5 Breast cancer; TGCT cis rs3820068 0.734 rs6669156 chr1:15905206 T/A cg05660106 chr1:15850417 CASP9 1.16 14.38 0.79 3.49e-28 Systolic blood pressure; TGCT cis rs11148252 0.633 rs9535888 chr13:52733206 C/G cg00495681 chr13:53174319 NA 0.52 4.79 0.4 4.64e-6 Lewy body disease; TGCT cis rs2239547 0.603 rs2276825 chr3:52886605 T/C cg10802521 chr3:52805072 NEK4 -0.65 -6.14 -0.48 1.02e-8 Schizophrenia; TGCT cis rs9818758 0.607 rs11552724 chr3:49156473 C/G cg07636037 chr3:49044803 WDR6 -1.04 -5.17 -0.42 9.28e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs763121 0.853 rs5757141 chr22:38957483 G/A cg06022373 chr22:39101656 GTPBP1 0.82 8.1 0.59 4.32e-13 Menopause (age at onset); TGCT cis rs4975616 0.686 rs37011 chr5:1348798 A/T cg26373071 chr5:1325741 CLPTM1L 0.16 4.59 0.38 1.08e-5 Lung cancer; TGCT cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg10117171 chr1:25599238 RHD -0.34 -5.48 -0.44 2.31e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs6665290 0.904 rs11578103 chr1:227189642 C/A cg10327440 chr1:227177885 CDC42BPA -1.0 -20.53 -0.88 1.06e-41 Myeloid white cell count; TGCT cis rs7760949 0.889 rs9396262 chr6:13927418 C/T cg27413430 chr6:13925136 RNF182 0.73 6.79 0.52 4.22e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs1395 0.710 rs72817533 chr2:27482612 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.65 8.48 0.61 5.54e-14 Blood metabolite levels; TGCT cis rs739401 0.611 rs7394974 chr11:3038868 C/T cg05729581 chr11:3078854 CARS -0.54 -5.13 -0.42 1.07e-6 Longevity; TGCT cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg03609598 chr5:56110824 MAP3K1 -0.63 -4.96 -0.41 2.22e-6 Initial pursuit acceleration; TGCT cis rs1865760 0.566 rs4529296 chr6:26083135 C/G cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs9814567 1.000 rs4423809 chr3:134300107 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.92 8.42 0.6 7.71e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs651907 0.613 rs1707618 chr3:101631207 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.5 4.86 0.4 3.54e-6 Colorectal cancer; TGCT cis rs7647973 0.626 rs1463728 chr3:49647404 T/A cg05785598 chr3:49045655 WDR6 0.41 4.63 0.38 9.16e-6 Menarche (age at onset); TGCT cis rs9905704 0.647 rs10221208 chr17:57047885 T/C cg05425664 chr17:57184151 TRIM37 -0.57 -4.58 -0.38 1.1e-5 Testicular germ cell tumor; TGCT cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg18876405 chr7:65276391 NA 0.37 5.85 0.47 4.02e-8 Calcium levels; TGCT cis rs3617 0.539 rs12629687 chr3:52950659 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.95 0.41 2.38e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1218582 0.772 rs1109815 chr1:154909268 A/G cg06221963 chr1:154839813 KCNN3 -0.73 -12.24 -0.74 4.41e-23 Prostate cancer; TGCT cis rs12497850 0.864 rs4955410 chr3:49181218 A/G cg18654377 chr3:49208889 KLHDC8B -0.38 -4.79 -0.4 4.61e-6 Parkinson's disease; TGCT cis rs4953076 0.573 rs7602070 chr2:44388614 G/A cg00619915 chr2:44497795 NA -0.23 -5.07 -0.41 1.41e-6 Height; TGCT cis rs912057 0.841 rs1294423 chr6:6743795 C/T cg06612196 chr6:6737390 NA 0.37 4.88 0.4 3.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs916888 0.773 rs199445 chr17:44817408 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.8 5.52 0.44 1.89e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7264396 0.561 rs6058387 chr20:34568092 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -4.85 -0.4 3.6e-6 Total cholesterol levels; TGCT cis rs2019872 1.000 rs2019872 chr17:2010318 C/T cg24156229 chr17:1948635 NA -0.37 -4.59 -0.38 1.06e-5 Schizophrenia; TGCT cis rs6938 0.534 rs1133322 chr15:75212357 A/G cg09165964 chr15:75287851 SCAMP5 0.52 4.87 0.4 3.4e-6 Breast cancer; TGCT cis rs7582180 0.606 rs12618908 chr2:100947026 A/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs921968 0.643 rs483172 chr2:219428299 A/G cg02176678 chr2:219576539 TTLL4 0.37 5.34 0.43 4.2e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7584330 0.518 rs74003109 chr2:238448150 C/T cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs933688 0.938 rs7720235 chr5:90659329 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.05 9.14 0.63 1.5e-15 Smoking behavior; TGCT cis rs11098499 0.821 rs10032151 chr4:120391628 C/T cg09307838 chr4:120376055 NA 0.69 6.56 0.51 1.31e-9 Corneal astigmatism; TGCT cis rs2302045 1.000 rs16843267 chr2:242039589 A/C cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs4372836 0.754 rs6709674 chr2:28989667 A/G cg09522027 chr2:28974177 PPP1CB -0.68 -6.95 -0.53 1.87e-10 Body mass index; TGCT cis rs7666738 0.830 rs6532719 chr4:99043691 A/G cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.652 rs557625 chr11:68634722 G/A cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7568458 0.905 rs6739015 chr2:85755357 A/G cg02493740 chr2:85810744 VAMP5 -0.27 -4.81 -0.4 4.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4824093 0.610 rs3761496 chr22:50246466 T/C cg14114931 chr22:50943910 LMF2 0.37 4.58 0.38 1.11e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1580019 0.563 rs10486509 chr7:32585443 C/G cg06627557 chr7:32535165 LSM5;AVL9 -1.1 -13.86 -0.78 5.72e-27 Cognitive ability; TGCT cis rs3829109 0.564 rs11789379 chr9:139285260 T/C cg13741927 chr9:139327495 INPP5E -0.23 -4.97 -0.41 2.14e-6 Peak insulin response;Acute insulin response; TGCT cis rs9911578 1.000 rs6503866 chr17:56619581 C/T cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.641 rs2748489 chr6:146331287 T/G cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.2e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg13695892 chr22:41940480 POLR3H -0.82 -8.43 -0.6 7.34e-14 Vitiligo; TGCT cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs1348850 0.768 rs57681892 chr2:178357645 G/C cg22681709 chr2:178499509 PDE11A -0.35 -4.53 -0.38 1.39e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4517514 0.509 rs10830417 chr11:89871940 A/G cg05041596 chr11:89867385 NAALAD2 0.52 4.61 0.38 9.86e-6 Trans fatty acid levels; TGCT cis rs2730260 0.537 rs56023468 chr7:158875329 T/C cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs7769051 0.522 rs3736725 chr6:133095172 A/G cg07930552 chr6:133119739 C6orf192 1.21 4.81 0.4 4.24e-6 Type 2 diabetes nephropathy; TGCT trans rs9929218 0.551 rs4783663 chr16:68720271 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.62 7.92 0.58 1.13e-12 Colorectal cancer; TGCT cis rs17473412 1.000 rs1047484 chr5:122680667 T/G cg15125798 chr5:122621645 NA -0.58 -5.2 -0.42 7.87e-7 Total body bone mineral density; TGCT cis rs9560113 0.959 rs9555802 chr13:112179504 T/C cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs9394169 0.875 rs1547669 chr6:33775641 A/G cg13859433 chr6:33739653 LEMD2 -0.33 -5.85 -0.47 4.02e-8 Essential tremor; TGCT cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg03188948 chr7:1209495 NA 0.64 5.38 0.43 3.61e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs185694 1.000 rs1099860 chr13:30883168 C/T cg07600127 chr13:30881527 KATNAL1 -0.87 -6.77 -0.52 4.55e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs6684514 1.000 rs2273833 chr1:156233189 C/T cg20302342 chr1:156215951 PAQR6 0.35 4.57 0.38 1.17e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7666738 0.830 rs7686456 chr4:99019695 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs8017423 0.935 rs8012299 chr14:90715822 G/T cg04374321 chr14:90722782 PSMC1 0.72 7.54 0.56 8.86e-12 Mortality in heart failure; TGCT cis rs739496 0.615 rs9300319 chr12:112064897 T/C cg10833066 chr12:111807467 FAM109A 0.36 5.22 0.42 7.28e-7 Platelet count; TGCT cis rs6840360 0.642 rs7676059 chr4:152393267 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.695 rs2225125 chr9:4998639 A/G cg02405213 chr9:5042618 JAK2 -0.73 -9.46 -0.65 2.54e-16 Pediatric autoimmune diseases; TGCT cis rs9914544 1.000 rs9914544 chr17:18787828 A/C cg26378065 chr17:18585709 ZNF286B 0.52 4.73 0.39 5.94e-6 Educational attainment (years of education); TGCT cis rs9733 0.596 rs6587516 chr1:150623221 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs8070740 0.898 rs8078914 chr17:5323924 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.77 0.39 5.1e-6 Menopause (age at onset); TGCT trans rs17685 0.712 rs1639620 chr7:75704090 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs936229 0.861 rs7180484 chr15:75115416 G/T cg10253484 chr15:75165896 SCAMP2 0.66 5.34 0.43 4.28e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs10838634 1.000 rs12273360 chr11:46889719 T/C cg18332754 chr11:46939436 LRP4 0.89 4.77 0.39 5.13e-6 Schizophrenia; TGCT cis rs2842992 0.513 rs7759086 chr6:160193853 A/G cg11366901 chr6:160182831 ACAT2 0.74 5.59 0.45 1.36e-7 Age-related macular degeneration (geographic atrophy); TGCT cis rs1865760 1.000 rs9467636 chr6:25919549 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.21 0.49 7.42e-9 Height; TGCT cis rs9807989 0.507 rs1592459 chr2:103031569 A/G cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs7267979 1.000 rs4815417 chr20:25379526 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3540 0.960 rs8030390 chr15:90943471 C/T cg22089800 chr15:90895588 ZNF774 0.79 4.63 0.38 8.98e-6 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7432375 0.799 rs4038578 chr3:136426822 A/T cg12473912 chr3:136751656 NA -0.34 -4.53 -0.38 1.35e-5 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9457247 1.000 rs364283 chr6:167383750 C/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs7017914 0.905 rs4078067 chr8:71956471 T/C cg23757474 chr8:71581111 LACTB2;XKR9 0.55 5.11 0.42 1.17e-6 Bone mineral density; TGCT cis rs7617480 0.617 rs7610519 chr3:48746427 C/G cg07636037 chr3:49044803 WDR6 0.77 6.37 0.5 3.33e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9916302 0.861 rs4795376 chr17:37669043 T/C cg15445000 chr17:37608096 MED1 0.32 4.66 0.39 8.18e-6 Glomerular filtration rate (creatinine); TGCT cis rs5771242 0.776 rs6010198 chr22:50610628 A/G cg08875078 chr22:50639485 SELO -0.51 -4.49 -0.37 1.63e-5 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg06212747 chr3:49208901 KLHDC8B 0.67 6.36 0.5 3.57e-9 Menarche (age at onset); TGCT cis rs1552244 0.882 rs28366039 chr3:10028988 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.88 5.74 0.46 6.73e-8 Alzheimer's disease; TGCT cis rs72945132 0.941 rs66803755 chr11:70117473 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.32 0.55 2.78e-11 Coronary artery disease; TGCT cis rs7675861 0.891 rs11945849 chr4:5850343 C/T cg14241509 chr4:6196512 JAKMIP1 -0.27 -5.07 -0.41 1.44e-6 Dysphagia; TGCT cis rs12220238 1.000 rs10824130 chr10:76008931 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.95 7.37 0.55 2.07e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7017914 0.967 rs2732091 chr8:71918423 C/T cg23757474 chr8:71581111 LACTB2;XKR9 0.54 5.08 0.41 1.37e-6 Bone mineral density; TGCT cis rs7647973 0.626 rs11709734 chr3:49745235 G/A cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs4700695 0.764 rs251278 chr5:65381826 G/A cg21114390 chr5:65439923 SFRS12 -0.58 -4.52 -0.38 1.43e-5 Facial morphology (factor 19); TGCT cis rs832540 0.656 rs702689 chr5:56177443 G/A cg24531977 chr5:56204891 C5orf35 -0.53 -5.12 -0.42 1.12e-6 Coronary artery disease; TGCT trans rs35851103 0.627 rs58602899 chr8:11848833 G/T cg06636001 chr8:8085503 FLJ10661 0.76 7.14 0.54 7.04e-11 Neuroticism; TGCT cis rs899997 1.000 rs7182567 chr15:79045054 A/G cg04896959 chr15:78267971 NA 0.33 4.66 0.39 8.03e-6 Coronary artery disease or large artery stroke; TGCT cis rs9911578 0.967 rs6503883 chr17:56917543 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.637 rs4646080 chr1:15826627 A/T cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs10875595 0.732 rs62378370 chr5:140679460 T/C cg24830062 chr5:140700576 TAF7 -0.63 -5.29 -0.43 5.35e-7 Pulmonary function decline; TGCT cis rs4389656 0.767 rs369769 chr5:6720712 T/C cg10857441 chr5:6722123 POLS -0.22 -4.86 -0.4 3.44e-6 Coronary artery disease; TGCT cis rs9611565 1.000 rs1109151 chr22:41752944 A/G cg17554472 chr22:41940697 POLR3H -0.46 -5.12 -0.42 1.13e-6 Vitiligo; TGCT cis rs11098499 0.863 rs34868248 chr4:120442430 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs427394 0.582 rs274667 chr5:6710771 A/G cg10857441 chr5:6722123 POLS 0.28 6.07 0.48 1.45e-8 Menopause (age at onset); TGCT cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg21672276 chr3:44754072 ZNF502 -0.41 -4.67 -0.39 7.86e-6 Depressive symptoms; TGCT cis rs2404602 1.000 rs12148786 chr15:76800362 A/G cg22467129 chr15:76604101 ETFA -0.47 -5.23 -0.43 6.85e-7 Blood metabolite levels; TGCT cis rs6988636 1.000 rs13261100 chr8:124190312 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1048238 0.506 rs12039892 chr1:16167974 A/G cg21385522 chr1:16154831 NA 0.58 6.61 0.51 1.03e-9 Systolic blood pressure; TGCT cis rs2439831 1.000 rs2444029 chr15:43737484 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT trans rs1005277 0.589 rs2749624 chr10:38529865 A/G cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs6964587 1.000 rs36021614 chr7:91717490 C/G cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs67311347 1.000 rs4973997 chr3:40460145 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs4776059 1.000 rs8026800 chr15:52933548 C/G cg25063058 chr15:52860530 ARPP19 0.51 4.64 0.38 8.56e-6 Schizophrenia; TGCT cis rs6969780 0.630 rs10238095 chr7:27196643 A/G cg17457637 chr7:27170717 HOXA4 -0.44 -4.61 -0.38 9.74e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.9 -0.4 2.95e-6 Prudent dietary pattern; TGCT cis rs66573146 0.831 rs6851488 chr4:6987412 C/T cg00086871 chr4:6988644 TBC1D14 0.96 4.89 0.4 3.1e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg12756686 chr19:29218302 NA 0.68 6.47 0.5 2e-9 Methadone dose in opioid dependence; TGCT cis rs6598955 0.671 rs8564 chr1:26605069 T/C cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs7552404 1.000 rs12126607 chr1:76217097 G/A cg03433033 chr1:76189801 ACADM 0.81 9.52 0.65 1.84e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17221829 0.733 rs7942295 chr11:89372341 T/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs7267979 1.000 rs2482919 chr20:25299756 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7043114 0.525 rs10820964 chr9:95041636 G/A cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.95e-5 Height; TGCT cis rs2014572 0.870 rs10426580 chr19:57756221 G/A cg24459738 chr19:57751996 ZNF805 -0.54 -5.4 -0.44 3.21e-7 Hyperactive-impulsive symptoms; TGCT cis rs2204008 0.577 rs11520050 chr12:38051839 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs6867032 1.000 rs61177713 chr5:2017255 G/A cg26168224 chr5:2018326 NA 0.44 8.03 0.59 6.26e-13 Gut microbiome composition (winter); TGCT trans rs208520 0.690 rs207094 chr6:66799009 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.83 -0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs1577917 0.958 rs2324840 chr6:86557620 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs12220777 1.000 rs11201660 chr10:81854531 A/G cg07370745 chr10:80921785 ZMIZ1 -0.29 -4.5 -0.37 1.56e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs1670533 0.932 rs2248083 chr4:1052166 A/C cg27284194 chr4:1044797 NA 0.7 5.91 0.47 3.12e-8 Recombination rate (females); TGCT cis rs7760949 0.888 rs6939712 chr6:13897246 T/C cg27413430 chr6:13925136 RNF182 0.54 4.94 0.41 2.44e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs988712 0.705 rs16917204 chr11:27668355 G/C cg10635145 chr11:27742435 BDNF -0.38 -5.25 -0.43 6.38e-7 Obesity; TGCT cis rs9486715 0.838 rs9320127 chr6:96865358 G/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs1153858 1.000 rs28679834 chr15:45616206 C/T cg14582100 chr15:45693742 SPATA5L1 0.45 5.06 0.41 1.48e-6 Homoarginine levels; TGCT cis rs2760061 0.626 rs596208 chr1:228117982 G/C cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.37e-9 Diastolic blood pressure; TGCT cis rs2235642 0.821 rs8051895 chr16:1602811 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.31 -5.23 -0.43 7.02e-7 Coronary artery disease; TGCT cis rs3892630 0.588 rs2112917 chr19:33317543 C/T cg22980127 chr19:33182716 NUDT19 0.75 6.02 0.48 1.81e-8 Red blood cell traits; TGCT cis rs9359856 0.510 rs17293240 chr6:90396370 C/T cg13799429 chr6:90582589 CASP8AP2 0.45 4.66 0.39 7.9e-6 Bipolar disorder; TGCT cis rs4891159 0.790 rs17059379 chr18:74160316 A/T cg24786174 chr18:74118243 ZNF516 0.53 7.34 0.55 2.46e-11 Longevity; TGCT cis rs7772486 0.875 rs2224121 chr6:146343214 G/A cg05347473 chr6:146136440 FBXO30 0.55 5.21 0.42 7.57e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs42648 0.596 rs6465251 chr7:89847881 C/G cg25739043 chr7:89950458 NA -0.49 -4.69 -0.39 7.02e-6 Homocysteine levels; TGCT cis rs7666738 0.830 rs28761309 chr4:98867393 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2046867 0.583 rs13316962 chr3:72911994 T/C cg25664220 chr3:72788482 NA -0.41 -5.43 -0.44 2.86e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1577917 1.000 rs117907570 chr6:86601283 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.71e-7 Response to antipsychotic treatment; TGCT cis rs3796352 1.000 rs36090694 chr3:53010742 T/C cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2456568 0.900 rs2511399 chr11:93682156 C/T cg26875233 chr11:93583750 C11orf90 0.42 5.4 0.44 3.3e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10751667 0.643 rs11246348 chr11:939476 G/C cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs13108904 0.539 rs13135102 chr4:1330983 A/C cg03303774 chr4:1407052 NA 0.38 6.07 0.48 1.45e-8 Obesity-related traits; TGCT cis rs11122272 0.735 rs2808585 chr1:231514218 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs67460515 0.665 rs28384382 chr3:160939141 C/T cg03342759 chr3:160939853 NMD3 -0.47 -4.87 -0.4 3.28e-6 Parkinson's disease; TGCT cis rs422249 0.819 rs174611 chr11:61627881 T/C cg01500311 chr11:61656094 FADS3 -0.33 -5.41 -0.44 3.14e-7 Trans fatty acid levels; TGCT cis rs2721195 0.549 rs2620666 chr8:145703413 T/C cg15320075 chr8:145703422 NA 0.74 8.18 0.59 2.87e-13 Age at first birth; TGCT cis rs6992820 0.967 rs4737418 chr8:56711267 A/G cg06880721 chr8:56792545 LYN -0.55 -4.74 -0.39 5.71e-6 Mean platelet volume; TGCT cis rs769267 1.000 rs3764567 chr19:19440066 C/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.57 -4.64 -0.38 8.62e-6 Tonsillectomy; TGCT cis rs9399135 0.967 rs4637662 chr6:135298158 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs682748 0.810 rs1482345 chr5:17114704 G/A cg23987134 chr5:17158319 LOC285696 -0.21 -4.9 -0.4 2.87e-6 Hippocampal atrophy; TGCT cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs561341 0.609 rs7209493 chr17:30197323 A/G cg13647721 chr17:30228624 UTP6 -0.63 -4.61 -0.38 9.72e-6 Hip circumference adjusted for BMI; TGCT cis rs9653442 0.564 rs7565895 chr2:100774773 G/A cg07810366 chr2:100720526 AFF3 -0.34 -5.13 -0.42 1.1e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs896854 0.967 rs10808671 chr8:95967372 A/G cg16049864 chr8:95962084 TP53INP1 -0.77 -10.92 -0.7 7.16e-20 Type 2 diabetes; TGCT cis rs7226408 0.857 rs7234586 chr18:34434634 G/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7727544 0.606 rs10060615 chr5:131708877 T/C cg24060327 chr5:131705240 SLC22A5 -0.51 -5.43 -0.44 2.85e-7 Blood metabolite levels; TGCT cis rs939574 0.512 rs908197 chr2:220144410 G/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.74 4.89 0.4 3.07e-6 Platelet distribution width; TGCT cis rs7659604 0.539 rs3217771 chr4:122739483 G/A cg06713675 chr4:122721982 EXOSC9 -0.69 -9.7 -0.66 6.92e-17 Type 2 diabetes; TGCT cis rs5769707 0.967 rs9616333 chr22:50050847 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.59 0.38 1.06e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs603446 0.967 rs180346 chr11:116612659 A/C cg20608306 chr11:116969690 SIK3 0.41 4.54 0.38 1.3e-5 Triglycerides; TGCT cis rs6087771 0.821 rs6058444 chr20:30315137 A/G cg18721089 chr20:30220636 NA -0.36 -4.46 -0.37 1.82e-5 Subcortical brain region volumes;Putamen volume; TGCT cis rs9914544 0.545 rs68046274 chr17:18785126 G/A cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs66573146 0.831 rs67602077 chr4:7024244 A/G cg01220768 chr4:7056774 TADA2B 0.41 5.07 0.41 1.43e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6540559 0.673 rs926346 chr1:209962204 A/T cg22029157 chr1:209979665 IRF6 0.75 5.58 0.45 1.45e-7 Cleft lip with or without cleft palate; TGCT cis rs2820315 0.867 rs2820322 chr1:201880300 T/C cg12730843 chr1:201915899 LMOD1 -0.26 -4.9 -0.4 2.91e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs10504229 0.679 rs72649132 chr8:58054615 G/A cg02725872 chr8:58115012 NA -0.38 -4.69 -0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.817 rs12198065 chr6:146385286 G/C cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1372520 0.745 rs2736994 chr4:90784528 A/G cg20003494 chr4:90757398 SNCA -0.6 -4.65 -0.39 8.35e-6 Neuroticism; TGCT cis rs56104184 0.830 rs17272658 chr19:49355405 C/T cg15549821 chr19:49342101 PLEKHA4 -0.84 -10.28 -0.68 2.68e-18 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs11025559 0.716 rs1596376 chr11:20454229 T/C cg19653624 chr11:20408972 PRMT3 -0.64 -5.07 -0.41 1.43e-6 Pursuit maintenance gain; TGCT cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs11167764 1.000 rs11167764 chr5:141479065 A/C cg08523384 chr5:141488047 NDFIP1 -0.23 -4.54 -0.38 1.31e-5 Crohn's disease; TGCT cis rs2242116 0.727 rs10865943 chr3:46969970 T/C cg02527881 chr3:46936655 PTH1R -0.28 -5.21 -0.42 7.75e-7 Birth weight; TGCT cis rs2456568 0.802 rs8181578 chr11:93637442 G/A cg14065697 chr11:93583672 C11orf90 -0.38 -4.74 -0.39 5.65e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2251381 0.750 rs2251186 chr21:30528880 G/A cg24692254 chr21:30365293 RNF160 0.74 6.96 0.53 1.76e-10 Selective IgA deficiency; TGCT cis rs2239547 0.562 rs35380116 chr3:52979178 A/G cg10802521 chr3:52805072 NEK4 0.64 6.1 0.48 1.26e-8 Schizophrenia; TGCT cis rs6138458 1.000 rs227632 chr20:24913729 G/A cg26195577 chr20:24973756 C20orf3 1.2 12.06 0.73 1.2e-22 Blood protein levels; TGCT cis rs950169 0.922 rs12906983 chr15:84931022 G/A cg11189052 chr15:85197271 WDR73 0.81 6.12 0.48 1.12e-8 Schizophrenia; TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg06873352 chr17:61820015 STRADA 0.58 6.38 0.5 3.2e-9 Prudent dietary pattern; TGCT cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.53 0.38 1.37e-5 Obesity-related traits; TGCT cis rs2153535 0.580 rs1414349 chr6:8472290 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs35934224 0.783 rs13053818 chr22:19859652 G/A cg11182965 chr22:19864308 TXNRD2 -0.39 -5.13 -0.42 1.1e-6 Glaucoma (primary open-angle); TGCT cis rs9914988 0.943 rs9891925 chr17:27104540 A/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs877282 0.945 rs17293517 chr10:778770 C/T cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs1055129 0.584 rs9895947 chr17:73908566 A/C cg08125733 chr17:73851984 WBP2 0.6 5.46 0.44 2.55e-7 White matter hyperintensity burden; TGCT trans rs4662986 0.579 rs72858968 chr2:130475906 G/T cg16461102 chr3:14508078 SLC6A6 0.41 6.92 0.53 2.1e-10 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2468186 0.583 rs2450068 chr8:120095859 C/G cg02248809 chr8:120845432 TAF2 -0.45 -4.83 -0.4 3.99e-6 Osteoprotegerin levels; TGCT cis rs7914558 0.966 rs10786725 chr10:104682357 T/C cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6450176 1.000 rs60652351 chr5:53306140 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs13108904 0.840 rs13149790 chr4:1262239 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.65 0.39 8.32e-6 Obesity-related traits; TGCT cis rs9443645 0.901 rs4415132 chr6:79554107 T/C cg09184832 chr6:79620586 NA -0.48 -5.35 -0.43 4.01e-7 Intelligence (multi-trait analysis); TGCT trans rs34816374 1 rs34816374 chr6:26949672 A/G cg20516262 chr7:155325649 CNPY1 0.63 7.11 0.54 7.99e-11 Lung cancer in ever smokers; TGCT trans rs208520 0.690 rs1318604 chr6:66825278 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.72 -0.69 2.28e-19 Exhaled nitric oxide output; TGCT trans rs3780486 0.846 rs7873903 chr9:33142728 G/A cg20290983 chr6:43655470 MRPS18A 1.19 14.23 0.79 7.61e-28 IgG glycosylation; TGCT cis rs9368481 0.645 rs10456350 chr6:26975581 A/C cg18867708 chr6:26865862 GUSBL1 0.38 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs72615157 0.606 rs941288 chr7:99776808 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.62 4.87 0.4 3.34e-6 Lung function (FEV1/FVC); TGCT cis rs854765 0.647 rs854808 chr17:18006634 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.72 7.52 0.56 9.79e-12 Total body bone mineral density; TGCT cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg16423285 chr20:60520624 NA -0.74 -9.17 -0.64 1.28e-15 Obesity-related traits; TGCT cis rs951366 0.903 rs823116 chr1:205720483 G/A cg17178900 chr1:205818956 PM20D1 0.41 4.56 0.38 1.19e-5 Menarche (age at onset); TGCT cis rs2204008 0.537 rs28680519 chr12:38502946 C/T cg13010199 chr12:38710504 ALG10B 0.55 4.71 0.39 6.6e-6 Bladder cancer; TGCT cis rs910316 0.935 rs11159119 chr14:75636967 C/T cg08847533 chr14:75593920 NEK9 -0.94 -10.45 -0.68 1.01e-18 Height; TGCT cis rs3026101 0.671 rs2407 chr17:5289028 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.23e-6 Body mass index; TGCT cis rs2404602 0.716 rs17362383 chr15:76650702 A/G cg26408565 chr15:76604113 ETFA -0.4 -5.27 -0.43 5.85e-7 Blood metabolite levels; TGCT cis rs6840360 1.000 rs751012 chr4:152602247 A/C cg17479576 chr4:152424074 FAM160A1 -0.52 -5.66 -0.45 9.86e-8 Intelligence (multi-trait analysis); TGCT cis rs13424612 1.000 rs10193610 chr2:240940618 A/G cg26363272 chr2:240904871 NDUFA10 0.3 5.06 0.41 1.46e-6 Odorant perception (isobutyraldehyde); TGCT cis rs6089584 0.586 rs1079755 chr20:60615262 G/A cg06108461 chr20:60628389 TAF4 -0.42 -5.27 -0.43 5.89e-7 Body mass index; TGCT cis rs2637266 0.703 rs846643 chr10:78516889 T/G cg18941641 chr10:78392320 NA 0.4 4.79 0.4 4.63e-6 Pulmonary function; TGCT cis rs28785552 0.966 rs7247272 chr19:53236331 C/T cg10871876 chr19:53194124 ZNF83 -0.58 -8.76 -0.62 1.22e-14 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs10193935 0.901 rs6733914 chr2:42674741 A/G cg27598129 chr2:42591480 NA 0.4 5.56 0.45 1.61e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7524258 0.900 rs2412151 chr1:7303216 G/C cg04342483 chr1:7259290 CAMTA1 -0.3 -4.48 -0.37 1.69e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7191700 0.578 rs243324 chr16:11354970 A/G cg00044050 chr16:11439710 C16orf75 0.84 8.69 0.62 1.79e-14 Multiple sclerosis; TGCT cis rs6089829 0.962 rs6062780 chr20:61666648 T/C cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs7772486 0.754 rs6910790 chr6:146255330 G/A cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs59698941 0.550 rs12652469 chr5:132182765 A/G cg27099455 chr5:132201840 GDF9;UQCRQ 0.29 4.94 0.41 2.52e-6 Apolipoprotein A-IV levels; TGCT cis rs2836974 0.897 rs1571709 chr21:40553980 T/C cg11644478 chr21:40555479 PSMG1 1.02 10.63 0.69 3.73e-19 Cognitive function; TGCT cis rs6546537 1.000 rs4852867 chr2:69831449 G/A cg10773587 chr2:69614142 GFPT1 -0.65 -5.82 -0.46 4.67e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs933688 1.000 rs2367353 chr5:90686568 G/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.89 8.17 0.59 2.94e-13 Smoking behavior; TGCT cis rs8016982 0.657 rs8021125 chr14:81704787 C/T cg02996355 chr14:81879375 NA -0.44 -4.5 -0.37 1.56e-5 Schizophrenia; TGCT cis rs514406 0.505 rs269290 chr1:53167027 A/T cg22166914 chr1:53195759 ZYG11B 0.44 7.66 0.57 4.64e-12 Monocyte count; TGCT cis rs231513 0.911 rs231511 chr17:41966335 T/C cg26893861 chr17:41843967 DUSP3 -0.75 -5.3 -0.43 5.18e-7 Cognitive function; TGCT cis rs7582180 0.630 rs13021801 chr2:100935129 C/A cg14675211 chr2:100938903 LONRF2 0.51 4.98 0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs60871478 0.636 rs4719520 chr7:875216 C/G cg00475322 chr7:917719 C7orf20 0.49 4.79 0.39 4.72e-6 Cerebrospinal P-tau181p levels; TGCT cis rs6964587 0.869 rs34791781 chr7:91532720 C/T cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs2243480 1.000 rs431318 chr7:65511597 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs10779751 0.734 rs2791658 chr1:11127871 A/G cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs7147624 0.532 rs72716459 chr14:66260654 C/T cg03016385 chr14:66212404 NA 0.52 6.0 0.47 2.03e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT trans rs2469997 1.000 rs2447179 chr8:120355775 A/G cg01792902 chr3:178864926 PIK3CA 0.78 6.66 0.51 7.93e-10 Hypertension (SNP x SNP interaction); TGCT cis rs6912958 0.582 rs242285 chr6:88070743 G/A cg08069147 chr6:88032118 GJB7;C6orf162 0.7 7.33 0.55 2.64e-11 Monocyte percentage of white cells; TGCT cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg23708337 chr7:1209742 NA 0.5 4.44 0.37 1.98e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8017423 0.904 rs11848894 chr14:90723660 C/A cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs6570726 0.935 rs408768 chr6:145871735 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs3617 0.652 rs60332615 chr3:52867595 C/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9788682 0.747 rs11637630 chr15:78899719 G/A cg24631222 chr15:78858424 CHRNA5 -0.88 -6.66 -0.51 7.79e-10 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT trans rs877282 0.853 rs11593836 chr10:756715 G/A cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs727505 0.721 rs56069273 chr7:124768604 G/A cg23710748 chr7:124431027 NA -0.25 -4.63 -0.38 9.13e-6 Lewy body disease; TGCT cis rs6700896 0.500 rs7549647 chr1:66088184 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs12681287 0.547 rs11992656 chr8:87534869 T/A cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT trans rs4332037 0.539 rs55773130 chr7:2070554 T/C cg25206134 chr2:45395956 NA 0.97 7.42 0.55 1.6e-11 Bipolar disorder; TGCT cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg12311346 chr5:56204834 C5orf35 0.66 6.81 0.52 3.82e-10 Initial pursuit acceleration; TGCT cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg22764044 chr5:178986830 RUFY1 0.42 4.53 0.38 1.38e-5 Lung cancer; TGCT cis rs3806843 0.966 rs2337516 chr5:140140853 A/G cg19875535 chr5:140030758 IK -0.37 -6.21 -0.49 7.38e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4788570 0.585 rs7499576 chr16:71789553 T/G cg06353428 chr16:71660113 MARVELD3 1.52 11.66 0.72 1.15e-21 Intelligence (multi-trait analysis); TGCT cis rs7552404 1.000 rs7533888 chr1:76160449 A/C cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2204008 0.777 rs11179774 chr12:38219559 A/C cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg27588902 chr6:42928151 GNMT -0.56 -6.66 -0.51 7.89e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9549367 0.673 rs3751413 chr13:113854715 C/T cg00898013 chr13:113819073 PROZ 0.49 6.46 0.5 2.19e-9 Platelet distribution width; TGCT cis rs7027203 0.828 rs10761288 chr9:96609363 C/T cg14396892 chr9:96623032 NA -0.25 -4.91 -0.4 2.78e-6 DNA methylation (variation); TGCT cis rs992157 0.932 rs1473901 chr2:219188838 C/T cg00012203 chr2:219082015 ARPC2 0.69 6.89 0.53 2.46e-10 Colorectal cancer; TGCT cis rs7216064 0.700 rs4791295 chr17:65997317 G/A cg12091567 chr17:66097778 LOC651250 -0.97 -7.46 -0.56 1.29e-11 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9393777 0.513 rs13210025 chr6:26654817 A/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs9787249 0.915 rs58589165 chr1:40213670 A/T cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs5750830 0.649 rs4384886 chr22:39793766 C/T cg05872129 chr22:39784769 NA -1.01 -11.59 -0.72 1.71e-21 Intelligence (multi-trait analysis); TGCT cis rs4879913 0.801 rs7849006 chr9:35592324 C/A cg18130437 chr9:35658183 CCDC107;RMRP -0.5 -4.95 -0.41 2.38e-6 Electroencephalogram traits; TGCT cis rs877426 0.555 rs7988568 chr13:114826751 C/T cg16820615 chr13:114884918 RASA3 0.33 5.2 0.42 8.08e-7 Facial morphology (factor 14, intercanthal width); TGCT cis rs4919669 0.668 rs10883763 chr10:104427825 C/T cg05855489 chr10:104503620 C10orf26 0.86 4.63 0.38 9.05e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs797680 0.856 rs2765545 chr1:93677269 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.29 -0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7772486 0.754 rs6932863 chr6:146021255 A/T cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.772 rs4845688 chr1:154884142 T/C cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs9942416 0.660 rs4704231 chr5:74986576 G/A cg19683494 chr5:74908142 NA 0.59 6.26 0.49 5.62e-9 Age-related disease endophenotypes; TGCT cis rs6964587 0.967 rs10231496 chr7:91741132 T/C cg17063962 chr7:91808500 NA 0.88 9.58 0.65 1.33e-16 Breast cancer; TGCT cis rs2832191 0.636 rs8131283 chr21:30516796 A/G cg24692254 chr21:30365293 RNF160 -0.61 -5.38 -0.43 3.62e-7 Dental caries; TGCT cis rs1801251 1.000 rs35085837 chr2:233624363 A/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT trans rs9650657 0.504 rs10093053 chr8:11037187 T/C cg15556689 chr8:8085844 FLJ10661 -0.85 -8.36 -0.6 1.06e-13 Neuroticism; TGCT cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg26531700 chr6:26746687 NA -0.7 -6.84 -0.52 3.25e-10 Schizophrenia; TGCT cis rs7267979 0.966 rs2227892 chr20:25264814 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9291683 0.530 rs4235346 chr4:9945296 C/T cg00071950 chr4:10020882 SLC2A9 -0.64 -7.56 -0.56 7.82e-12 Bone mineral density; TGCT cis rs2243480 1.000 rs160643 chr7:65558222 C/T cg20637647 chr7:64974828 NA 0.8 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs4727027 0.635 rs12111923 chr7:148885877 G/A cg23583168 chr7:148888333 NA -0.69 -7.75 -0.57 2.82e-12 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs3809863 0.646 rs9899121 chr17:45395144 C/T cg25173405 chr17:45401733 C17orf57 -0.43 -4.71 -0.39 6.52e-6 Glaucoma (primary open-angle); TGCT cis rs4927850 0.881 rs7630489 chr3:195753401 T/C cg22891161 chr3:195456627 MUC20 -0.23 -5.38 -0.44 3.53e-7 Pancreatic cancer; TGCT cis rs2832191 0.791 rs2832186 chr21:30484151 A/C cg24692254 chr21:30365293 RNF160 -0.92 -10.25 -0.68 3.21e-18 Dental caries; TGCT cis rs6840360 0.532 rs4235221 chr4:152511193 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs1830230 chr4:99026186 G/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg14983838 chr19:29218262 NA 0.83 6.81 0.52 3.8e-10 Methadone dose in opioid dependence; TGCT cis rs2439831 0.557 rs13329084 chr15:44151063 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.8 -5.64 -0.45 1.1e-7 Lung cancer in ever smokers; TGCT cis rs58688157 0.705 rs12290989 chr11:615010 G/T cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs6964587 1.000 rs10264666 chr7:91578639 G/A cg17063962 chr7:91808500 NA -0.91 -9.88 -0.66 2.45e-17 Breast cancer; TGCT cis rs7010267 0.805 rs2062375 chr8:119977792 G/C cg17171407 chr8:119960777 TNFRSF11B 0.33 6.37 0.5 3.28e-9 Total body bone mineral density (age 45-60); TGCT cis rs174479 0.677 rs174463 chr11:61657838 G/A cg19610905 chr11:61596333 FADS2 0.58 5.05 0.41 1.56e-6 Sphingolipid levels; TGCT cis rs116095464 0.614 rs28736753 chr5:274081 G/A cg22857025 chr5:266934 NA -0.33 -6.34 -0.49 3.98e-9 Breast cancer; TGCT cis rs7824557 0.564 rs12547100 chr8:11242632 G/A cg21775007 chr8:11205619 TDH -0.71 -6.97 -0.53 1.7e-10 Retinal vascular caliber; TGCT cis rs593982 1.000 rs470360 chr11:65500530 T/C cg08755490 chr11:65554678 OVOL1 1.42 12.09 0.74 1.03e-22 Atopic dermatitis; TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg02493798 chr17:6899577 ALOX12 -0.43 -4.82 -0.4 4.17e-6 Tonsillectomy; TGCT cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs736408 0.500 rs2878762 chr3:52919002 T/C cg10802521 chr3:52805072 NEK4 -0.62 -6.2 -0.49 7.62e-9 Bipolar disorder; TGCT cis rs4272321 1 rs4272321 chr7:157951835 A/G cg06400119 chr7:158046222 PTPRN2 0.37 5.87 0.47 3.82e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2299587 0.775 rs10113677 chr8:17767684 T/A cg01800426 chr8:17659068 MTUS1 -0.62 -5.24 -0.43 6.56e-7 Economic and political preferences; TGCT cis rs28595532 0.920 rs114684527 chr4:119749252 G/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9527 0.568 rs1926036 chr10:104883812 C/T cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs2836974 0.897 rs13339986 chr21:40605982 T/C cg11644478 chr21:40555479 PSMG1 0.94 9.36 0.64 4.43e-16 Cognitive function; TGCT cis rs832540 0.556 rs4146565 chr5:56093825 T/C cg24531977 chr5:56204891 C5orf35 -0.54 -5.34 -0.43 4.33e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs1593572 chr4:98979322 A/G cg18180107 chr4:99064573 C4orf37 -0.52 -4.85 -0.4 3.58e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -6.07 -0.48 1.44e-8 Type 2 diabetes; TGCT cis rs6840360 0.606 rs2709813 chr4:152357444 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs7927771 0.725 rs11570094 chr11:47359706 A/C cg14716172 chr11:46724544 ZNF408 -0.17 -4.54 -0.38 1.32e-5 Subjective well-being; TGCT cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs769267 0.930 rs10422819 chr19:19643028 C/A cg03709012 chr19:19516395 GATAD2A 0.74 6.07 0.48 1.44e-8 Tonsillectomy; TGCT cis rs7027203 0.828 rs4744291 chr9:96598297 A/G cg13679303 chr9:96623674 NA -0.66 -10.78 -0.7 1.64e-19 DNA methylation (variation); TGCT cis rs1878931 0.697 rs1044390 chr16:3432594 T/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.97 11.89 0.73 3.25e-22 Body mass index (adult); TGCT cis rs77372450 0.551 rs61663448 chr5:157077191 T/C cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.48e-6 Bipolar disorder (body mass index interaction); TGCT cis rs12497850 0.931 rs7621015 chr3:49016056 A/G cg06212747 chr3:49208901 KLHDC8B 0.6 5.43 0.44 2.82e-7 Parkinson's disease; TGCT cis rs72781680 0.768 rs112139157 chr2:24150783 A/C cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs72627509 0.904 rs781663 chr4:57781754 A/G cg26694713 chr4:57773883 REST 0.73 6.57 0.51 1.26e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7909074 1.000 rs10751361 chr10:45398186 C/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.38 -0.44 3.57e-7 Mean corpuscular volume; TGCT cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg23262073 chr20:60523788 NA 0.31 4.98 0.41 2.08e-6 Obesity-related traits; TGCT cis rs4819052 0.959 rs9976074 chr21:46655638 G/T cg06618935 chr21:46677482 NA -0.33 -4.55 -0.38 1.27e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6460942 0.915 rs7803002 chr7:12306738 C/T cg06484146 chr7:12443880 VWDE -0.45 -4.68 -0.39 7.41e-6 Coronary artery disease; TGCT cis rs5769765 0.908 rs4058453 chr22:50250297 T/C cg22709217 chr22:50311962 ALG12;CRELD2 0.97 6.32 0.49 4.22e-9 Schizophrenia; TGCT cis rs921968 0.541 rs593888 chr2:219427597 A/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2702888 0.563 rs2741064 chr8:6760152 C/T cg26795848 chr8:6756730 NA 0.28 5.63 0.45 1.15e-7 Blood pressure; TGCT cis rs10504229 0.679 rs12679941 chr8:58051812 G/T cg11062466 chr8:58055876 NA 0.34 4.64 0.38 8.58e-6 Developmental language disorder (linguistic errors); TGCT cis rs801193 1.000 rs11773829 chr7:66141074 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.14 -0.42 1.06e-6 Aortic root size; TGCT cis rs6665290 0.904 rs7541033 chr1:227188371 C/A cg10327440 chr1:227177885 CDC42BPA -0.98 -19.78 -0.87 3.72e-40 Myeloid white cell count; TGCT cis rs2276314 1.000 rs56050783 chr18:33553791 A/G cg19628046 chr18:33552617 C18orf21 0.52 4.46 0.37 1.8e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs7954584 0.531 rs10840631 chr12:122373729 C/T cg22168489 chr12:122356033 WDR66 0.22 4.78 0.39 4.96e-6 Mean corpuscular volume; TGCT cis rs6840360 0.615 rs28659854 chr4:152607442 T/C cg22705602 chr4:152727874 NA -0.32 -5.44 -0.44 2.76e-7 Intelligence (multi-trait analysis); TGCT cis rs797680 0.964 rs4000699 chr1:93779805 C/T cg17826107 chr1:92977322 EVI5 -0.23 -5.13 -0.42 1.1e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9814567 1.000 rs7374325 chr3:134275601 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.11 -0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1215050 0.791 rs6532702 chr4:98766641 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9291683 0.609 rs36084205 chr4:10028678 A/C cg00071950 chr4:10020882 SLC2A9 0.7 9.43 0.65 3.06e-16 Bone mineral density; TGCT cis rs72615157 0.612 rs7786505 chr7:99817585 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.64 5.04 0.41 1.63e-6 Lung function (FEV1/FVC); TGCT cis rs1691799 0.836 rs1168334 chr12:66760972 A/G cg16791601 chr12:66731901 HELB -0.28 -6.03 -0.48 1.74e-8 White blood cell count (basophil); TGCT cis rs9394841 0.536 rs6899876 chr6:41796970 A/G cg08135965 chr6:41755394 TOMM6 0.48 4.66 0.39 8.1e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs5750830 0.594 rs9611166 chr22:39775268 T/C cg24399712 chr22:39784796 NA -0.95 -11.01 -0.7 4.37e-20 Intelligence (multi-trait analysis); TGCT trans rs916888 0.773 rs199534 chr17:44824213 T/G cg10053473 chr17:62856997 LRRC37A3 -0.46 -6.76 -0.52 4.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6940638 0.956 rs72838268 chr6:27021173 A/G cg16898833 chr6:26189333 HIST1H4D 0.78 5.81 0.46 5.05e-8 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.593 rs6737502 chr2:100862903 C/T cg07810366 chr2:100720526 AFF3 -0.41 -6.26 -0.49 5.76e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs908922 0.676 rs7529136 chr1:152516389 T/C cg20991723 chr1:152506922 NA 0.45 6.11 0.48 1.18e-8 Hair morphology; TGCT cis rs2777491 0.540 rs7164684 chr15:41705008 G/T cg18705301 chr15:41695430 NDUFAF1 -0.93 -16.85 -0.83 7.39e-34 Ulcerative colitis; TGCT cis rs1375194 0.606 rs2044644 chr2:33817559 A/G cg04131969 chr2:33951647 MYADML -0.56 -4.86 -0.4 3.51e-6 Response to antidepressants in depression; TGCT cis rs7586879 0.789 rs11688754 chr2:25133885 C/T cg01884057 chr2:25150051 NA 0.27 4.57 0.38 1.17e-5 Body mass index; TGCT cis rs17376456 0.741 rs12374432 chr5:93481348 C/A cg25358565 chr5:93447407 FAM172A 0.97 8.35 0.6 1.11e-13 Diabetic retinopathy; TGCT cis rs611744 0.967 rs635219 chr8:109229243 C/T cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs950776 0.642 rs922691 chr15:78963994 A/G cg21242079 chr15:79101063 ADAMTS7 -0.32 -4.99 -0.41 1.99e-6 Sudden cardiac arrest; TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg18722840 chr3:134321018 KY 0.38 6.68 0.51 7.25e-10 Breast cancer; TGCT cis rs12681288 0.523 rs73176528 chr8:961962 G/A cg04851639 chr8:1020857 NA -0.3 -5.08 -0.41 1.36e-6 Schizophrenia; TGCT cis rs10791323 0.604 rs10791324 chr11:133704065 T/C cg03690763 chr11:133734501 NA -0.35 -5.39 -0.44 3.46e-7 Childhood ear infection; TGCT cis rs7666738 0.822 rs17484018 chr4:98988960 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs4455778 0.561 rs10243463 chr7:49081185 T/G cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs1865760 0.516 rs9358903 chr6:26061949 A/C cg17042849 chr6:26104293 HIST1H4C -0.66 -5.85 -0.47 4.02e-8 Height; TGCT cis rs713587 1.000 rs2384054 chr2:25156773 T/C cg15423357 chr2:25149977 NA 0.63 6.43 0.5 2.55e-9 Body mass index in non-asthmatics; TGCT cis rs10992471 0.603 rs11794346 chr9:95247288 C/T cg14631576 chr9:95140430 CENPP -0.3 -4.54 -0.38 1.3e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4824093 0.610 rs77128035 chr22:50241024 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.45 4.65 0.39 8.43e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10504229 1.000 rs59797486 chr8:58174435 T/C cg08280861 chr8:58055591 NA 0.34 4.67 0.39 7.83e-6 Developmental language disorder (linguistic errors); TGCT cis rs6750047 0.605 rs2121260 chr2:38268763 T/G cg07380506 chr2:38303506 CYP1B1 0.59 5.34 0.43 4.23e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs3806843 0.576 rs246047 chr5:140328337 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs12142240 0.698 rs932816 chr1:46859749 G/A cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs9467773 1.000 rs9295695 chr6:26528250 C/T cg09904177 chr6:26538194 HMGN4 -0.68 -6.89 -0.53 2.52e-10 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs9296092 0.517 rs7743064 chr6:33470529 C/T cg13560919 chr6:33536144 NA -0.22 -4.49 -0.37 1.6e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT trans rs1974653 0.672 rs11703058 chr22:20075048 G/A cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Vitiligo; TGCT cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg22800045 chr5:56110881 MAP3K1 0.54 4.49 0.37 1.58e-5 Initial pursuit acceleration; TGCT cis rs36051895 0.589 rs7038763 chr9:5076399 T/C cg02405213 chr9:5042618 JAK2 -0.85 -12.57 -0.75 7.24e-24 Pediatric autoimmune diseases; TGCT cis rs12497850 0.931 rs9311434 chr3:48884147 T/C cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs9902453 0.765 rs2729448 chr17:28091953 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.83 -8.18 -0.59 2.86e-13 Coffee consumption (cups per day); TGCT cis rs7223966 1.000 rs8075273 chr17:61728881 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.57 0.38 1.16e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg00786635 chr1:25594202 NA -0.54 -5.68 -0.45 8.94e-8 Erythrocyte sedimentation rate; TGCT cis rs7552404 0.920 rs2788654 chr1:76219569 C/T cg03433033 chr1:76189801 ACADM 0.75 8.76 0.62 1.19e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10782582 0.609 rs5745547 chr1:76378275 G/C cg10523679 chr1:76189770 ACADM -0.58 -5.24 -0.43 6.73e-7 Daytime sleep phenotypes; TGCT cis rs796364 1.000 rs281794 chr2:200846666 C/T cg17644776 chr2:200775616 C2orf69 0.31 4.87 0.4 3.37e-6 Schizophrenia; TGCT cis rs1799949 1.000 rs8070085 chr17:41341984 C/T cg05368731 chr17:41323189 NBR1 -0.98 -11.0 -0.7 4.67e-20 Menopause (age at onset); TGCT cis rs11190604 1.000 rs2495759 chr10:102320363 C/T cg16342193 chr10:102329863 NA -0.41 -5.35 -0.43 4.04e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs174479 0.743 rs174464 chr11:61657926 A/G cg19610905 chr11:61596333 FADS2 0.58 5.05 0.41 1.56e-6 Sphingolipid levels; TGCT cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg25767906 chr1:53392781 SCP2 0.6 7.27 0.55 3.5e-11 Monocyte count; TGCT cis rs9653442 0.622 rs11685341 chr2:100636757 A/G cg22139774 chr2:100720529 AFF3 0.4 7.07 0.54 9.96e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg07157834 chr1:205819609 PM20D1 0.43 6.75 0.52 4.97e-10 Menarche (age at onset); TGCT cis rs11148252 0.904 rs7321964 chr13:53040822 A/G cg00495681 chr13:53174319 NA 0.61 6.3 0.49 4.83e-9 Lewy body disease; TGCT cis rs9640161 0.830 rs17173682 chr7:150059602 A/G cg10018233 chr7:150070692 REPIN1 0.31 4.62 0.38 9.57e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg19626725 chr5:178986131 RUFY1 0.47 5.83 0.46 4.6e-8 Lung cancer; TGCT cis rs7975161 0.630 rs6539128 chr12:104618454 A/G cg25273343 chr12:104657179 TXNRD1 -0.42 -5.75 -0.46 6.64e-8 Toenail selenium levels; TGCT cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.92 0.4 2.75e-6 Electroencephalogram traits; TGCT cis rs2013441 1.000 rs2703772 chr17:20131453 C/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs7267979 0.586 rs1007707 chr20:25190598 A/G cg16686733 chr20:25566563 NINL 0.53 5.41 0.44 3.06e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs600231 0.665 rs1784859 chr11:65220749 A/G cg17120908 chr11:65337727 SSSCA1 0.51 4.52 0.38 1.45e-5 Bone mineral density; TGCT cis rs711245 0.573 rs7570763 chr2:36800589 A/C cg01206211 chr2:36825736 FEZ2 -0.31 -4.91 -0.4 2.78e-6 Height; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg11905131 chr22:24372483 LOC391322 0.68 5.41 0.44 3.15e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1215050 0.904 rs9307215 chr4:98813965 A/G cg05340658 chr4:99064831 C4orf37 0.46 5.57 0.45 1.49e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg02675527 chr2:114030824 PAX8;LOC440839 -0.5 -6.65 -0.51 8.34e-10 Lymphocyte counts; TGCT cis rs61990749 0.597 rs8003691 chr14:78211225 A/G cg02301378 chr14:78227641 SNW1;C14orf178 0.62 4.58 0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs1865760 0.566 rs9358902 chr6:26058570 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.1e-11 Height; TGCT cis rs2549003 1.000 rs10068129 chr5:131821246 A/G cg02551604 chr5:131831745 NA 0.92 12.4 0.74 1.83e-23 Asthma (sex interaction); TGCT cis rs11105298 0.891 rs11105314 chr12:89924559 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs780096 0.546 rs35073769 chr2:27731376 C/T cg12000995 chr2:27665139 KRTCAP3 -0.38 -4.66 -0.39 8.15e-6 Total body bone mineral density; TGCT cis rs3820068 0.603 rs6429768 chr1:15963531 G/A cg05660106 chr1:15850417 CASP9 0.83 8.19 0.59 2.78e-13 Systolic blood pressure; TGCT cis rs7666738 0.546 rs9993299 chr4:98815976 G/A cg17366294 chr4:99064904 C4orf37 0.65 6.1 0.48 1.27e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs77372450 0.551 rs11134891 chr5:157103373 G/A cg12606933 chr5:157078573 SOX30 -0.42 -4.75 -0.39 5.51e-6 Bipolar disorder (body mass index interaction); TGCT cis rs1371867 0.775 rs3020183 chr8:101233297 A/T cg00191853 chr8:101177733 SPAG1 0.25 4.96 0.41 2.24e-6 Atrioventricular conduction; TGCT cis rs2996428 0.709 rs12127399 chr1:3721609 G/A cg17848003 chr1:3704513 LRRC47 0.17 4.57 0.38 1.14e-5 Red cell distribution width; TGCT cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg14416726 chr6:151773293 C6orf211;RMND1 -1.05 -14.4 -0.79 3.16e-28 Menarche (age at onset); TGCT cis rs4149178 0.656 rs11753396 chr6:43290742 A/C cg07522644 chr6:43142093 SRF 0.7 4.99 0.41 1.96e-6 Urate levels; TGCT cis rs17108533 0.588 rs12893741 chr14:71302862 A/G cg23900759 chr14:71108106 TTC9 1.15 4.79 0.39 4.73e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs7147624 0.572 rs72714470 chr14:65979173 G/A cg03016385 chr14:66212404 NA 0.6 6.75 0.52 4.98e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs910316 1.000 rs10146482 chr14:75574087 C/T cg08847533 chr14:75593920 NEK9 0.97 11.14 0.71 2.07e-20 Height; TGCT cis rs12291225 0.546 rs12795545 chr11:14355564 G/A cg19336497 chr11:14380999 RRAS2 -0.45 -7.25 -0.55 3.87e-11 Sense of smell; TGCT cis rs10883723 0.810 rs7079810 chr10:104243883 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs35306767 0.903 rs7067865 chr10:908387 C/T cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs763014 0.931 rs2071981 chr16:630025 C/G cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs7043114 0.507 rs10761154 chr9:95144086 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.59 -0.45 1.36e-7 Height; TGCT cis rs4819052 0.851 rs9974628 chr21:46672647 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8028182 0.636 rs4886712 chr15:75812888 C/T cg20655648 chr15:75932815 IMP3 0.59 4.62 0.38 9.55e-6 Sudden cardiac arrest; TGCT cis rs2236918 0.710 rs2526700 chr1:242019999 C/A cg04158730 chr1:242011433 EXO1 0.58 5.48 0.44 2.29e-7 Menopause (age at onset); TGCT cis rs2455799 0.573 rs2654650 chr3:15779214 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs6089584 0.566 rs6061964 chr20:60607536 G/A cg13770153 chr20:60521292 NA -0.39 -4.77 -0.39 5.17e-6 Body mass index; TGCT cis rs10782582 0.609 rs78556436 chr1:76352875 G/A cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs933688 1.000 rs4382199 chr5:90744228 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.03 8.7 0.62 1.68e-14 Smoking behavior; TGCT cis rs8077889 0.672 rs1230397 chr17:41844689 A/G cg26893861 chr17:41843967 DUSP3 1.15 21.87 0.89 2.21e-44 Triglycerides; TGCT cis rs12477438 0.834 rs1563106 chr2:99701381 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.12 -0.48 1.13e-8 Chronic sinus infection; TGCT cis rs10504229 0.817 rs58957714 chr8:58195864 G/A cg08280861 chr8:58055591 NA 0.38 4.46 0.37 1.81e-5 Developmental language disorder (linguistic errors); TGCT cis rs72781680 0.821 rs17046004 chr2:24144873 A/G cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs4563143 0.663 rs2218396 chr19:29236392 C/T cg04546413 chr19:29218101 NA 0.74 6.54 0.51 1.46e-9 Methadone dose in opioid dependence; TGCT cis rs10875746 0.551 rs1471997 chr12:48723595 G/A cg20731937 chr12:48336164 NA 0.57 4.5 0.37 1.52e-5 Longevity (90 years and older); TGCT cis rs1799949 0.929 rs4792988 chr17:41437547 T/C cg10047753 chr17:41438598 NA 0.85 7.86 0.58 1.56e-12 Menopause (age at onset); TGCT cis rs3820928 0.874 rs4144328 chr2:227790187 A/C cg11843606 chr2:227700838 RHBDD1 -0.53 -4.77 -0.39 5.13e-6 Pulmonary function; TGCT cis rs3096299 0.933 rs2965824 chr16:89455306 A/G cg06640241 chr16:89574553 SPG7 0.66 6.5 0.5 1.76e-9 Multiple myeloma (IgH translocation); TGCT cis rs6752107 0.936 rs10192702 chr2:234206750 A/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.71 0.39 6.47e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7010267 0.642 rs9969672 chr8:120006080 T/A cg17171407 chr8:119960777 TNFRSF11B 0.32 6.05 0.48 1.62e-8 Total body bone mineral density (age 45-60); TGCT cis rs7572733 0.534 rs10211202 chr2:198771941 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.11 0.42 1.21e-6 Dermatomyositis; TGCT cis rs4631830 0.863 rs2611507 chr10:51518673 T/C cg10326726 chr10:51549505 MSMB -0.27 -5.3 -0.43 5.18e-7 Prostate-specific antigen levels; TGCT cis rs931127 0.547 rs3886859 chr11:65458310 C/T cg27068330 chr11:65405492 SIPA1 -0.63 -6.32 -0.49 4.26e-9 Systemic lupus erythematosus; TGCT cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.87 0.4 3.32e-6 Menopause (age at onset); TGCT trans rs941408 0.963 rs1640267 chr19:2789337 T/C cg19676328 chr12:49525230 TUBA1B -0.84 -7.6 -0.56 6.46e-12 Total cholesterol levels; TGCT cis rs7929679 0.846 rs11032858 chr11:34794889 G/A cg18414381 chr11:34642885 EHF -0.23 -4.6 -0.38 1.03e-5 Chronic obstructive pulmonary disease-related biomarkers;Lung disease severity in cystic fibrosis; TGCT cis rs7226408 0.857 rs11664211 chr18:34461496 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs769267 0.896 rs10405625 chr19:19579046 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.73 0.46 7.3e-8 Tonsillectomy; TGCT cis rs9952991 0.566 rs482160 chr18:12855646 A/G cg23598886 chr18:12777645 NA 0.55 4.77 0.39 5.06e-6 Inflammatory skin disease; TGCT cis rs6964587 0.647 rs38801 chr7:92046327 G/T cg17063962 chr7:91808500 NA -0.59 -4.99 -0.41 2.03e-6 Breast cancer; TGCT cis rs1862618 0.573 rs185220 chr5:56205357 A/G cg03609598 chr5:56110824 MAP3K1 -0.61 -4.45 -0.37 1.9e-5 Initial pursuit acceleration; TGCT cis rs950169 0.580 rs11636189 chr15:85193554 G/A cg17173187 chr15:85201210 NMB 0.59 6.75 0.52 5.05e-10 Schizophrenia; TGCT cis rs2228479 0.850 rs3785281 chr16:89824263 G/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7647973 1.000 rs2312462 chr3:49601255 A/G cg07636037 chr3:49044803 WDR6 0.62 5.14 0.42 1.06e-6 Menarche (age at onset); TGCT cis rs7614311 0.731 rs56126667 chr3:63866286 A/G cg22134162 chr3:63841271 THOC7 -0.39 -5.12 -0.42 1.14e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs1552244 0.882 rs13062917 chr3:10017032 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs4665809 1.000 rs4233709 chr2:26291493 C/T cg22920501 chr2:26401640 FAM59B 0.72 5.76 0.46 6.28e-8 Gut microbiome composition (summer); TGCT cis rs7818688 0.697 rs74633621 chr8:95981037 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs782590 0.764 rs2054728 chr2:55818419 C/T cg03859395 chr2:55845619 SMEK2 0.83 9.78 0.66 4.33e-17 Metabolic syndrome; TGCT cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg18230493 chr5:56204884 C5orf35 -0.69 -5.98 -0.47 2.21e-8 Initial pursuit acceleration; TGCT cis rs10254284 0.959 rs10275989 chr7:28159696 A/G cg24719020 chr7:27187943 HOXA6 -0.32 -4.56 -0.38 1.22e-5 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs875971 0.862 rs1167408 chr7:65556108 G/A cg11764359 chr7:65958608 NA -0.56 -4.82 -0.4 4.1e-6 Aortic root size; TGCT cis rs13326165 0.715 rs11718125 chr3:52379420 T/C cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.36e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1371867 0.846 rs1660346 chr8:101312497 A/G cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg10047753 chr17:41438598 NA 0.96 9.49 0.65 2.15e-16 Menopause (age at onset); TGCT cis rs6089584 1.000 rs6089591 chr20:60570548 A/C cg13770153 chr20:60521292 NA -0.47 -6.05 -0.48 1.61e-8 Body mass index; TGCT cis rs2046867 0.908 rs6779684 chr3:72787586 G/A cg25664220 chr3:72788482 NA -0.56 -7.03 -0.53 1.25e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9527 0.590 rs12415199 chr10:104895536 T/C cg15744005 chr10:104629667 AS3MT -0.43 -4.94 -0.41 2.45e-6 Arsenic metabolism; TGCT cis rs6896969 0.510 rs10042027 chr5:40428811 G/A cg01087697 chr5:40835557 RPL37 0.57 5.11 0.42 1.2e-6 Multiple sclerosis; TGCT cis rs10779751 0.887 rs2300095 chr1:11265717 A/G cg08854313 chr1:11322531 MTOR 0.99 9.21 0.64 1.04e-15 Body mass index; TGCT cis rs10894604 0.558 rs11223204 chr11:132652554 A/G cg16639665 chr11:133402497 OPCML 0.44 4.46 0.37 1.79e-5 Waist-hip ratio; TGCT trans rs6089829 0.855 rs6062781 chr20:61667128 G/A cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1218582 0.682 rs12046459 chr1:154912017 A/C cg03351412 chr1:154909251 PMVK 0.52 4.87 0.4 3.31e-6 Prostate cancer; TGCT cis rs62103177 0.810 rs62096745 chr18:77619135 A/G cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs9868809 0.772 rs2302295 chr3:48690110 T/C cg15315015 chr3:49131774 QRICH1 0.8 4.58 0.38 1.1e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs60154123 0.505 rs115881613 chr1:210040369 C/T cg21951975 chr1:209979733 IRF6 0.69 5.18 0.42 8.74e-7 Coronary artery disease; TGCT cis rs174601 0.861 rs174550 chr11:61571478 T/C cg19610905 chr11:61596333 FADS2 -1.07 -12.03 -0.73 1.43e-22 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs12188164 0.686 rs72711370 chr5:421057 A/C cg26850624 chr5:429559 AHRR -0.21 -4.96 -0.41 2.23e-6 Cystic fibrosis severity; TGCT cis rs9906944 0.707 rs12942084 chr17:47114392 A/G cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.61 0.38 9.76e-6 Renal cell carcinoma; TGCT cis rs2229238 0.911 rs60368585 chr1:154509340 T/C cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs4455778 0.580 rs10259971 chr7:49085752 A/G cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs4389656 0.743 rs34681760 chr5:6712834 T/C cg10857441 chr5:6722123 POLS -0.22 -4.87 -0.4 3.27e-6 Coronary artery disease; TGCT cis rs7000551 0.527 rs11783730 chr8:22244897 C/T cg12081754 chr8:22256438 SLC39A14 0.34 4.93 0.4 2.58e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs8032315 0.965 rs4932373 chr15:91429287 A/C cg04510874 chr15:91427884 FES 0.52 5.76 0.46 6.28e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs2880765 0.566 rs11630381 chr15:86012503 A/G cg13263323 chr15:86062960 AKAP13 -0.21 -4.66 -0.39 8e-6 Coronary artery disease; TGCT cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg18867708 chr6:26865862 GUSBL1 -0.38 -5.03 -0.41 1.65e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs303386 0.581 rs4000190 chr1:99592566 C/T cg03593336 chr1:99471295 LPPR5 0.22 4.75 0.39 5.51e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors);Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin); TGCT cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2456568 0.564 rs4608039 chr11:93624799 C/G cg17595323 chr11:93583763 C11orf90 0.46 6.34 0.49 3.82e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9467711 0.745 rs9467714 chr6:26340785 C/T cg16898833 chr6:26189333 HIST1H4D 0.97 4.61 0.38 9.98e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7216064 0.684 rs8182243 chr17:66018505 T/C cg12091567 chr17:66097778 LOC651250 1.07 8.8 0.62 9.68e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs11711311 0.712 rs6764048 chr3:113332859 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 0.6 4.88 0.4 3.15e-6 IgG glycosylation; TGCT cis rs4319547 0.774 rs7954006 chr12:123131824 A/C cg23029597 chr12:123009494 RSRC2 0.28 4.83 0.4 4e-6 Body mass index; TGCT cis rs2180341 0.532 rs6933893 chr6:127707250 A/G cg24812749 chr6:127587940 RNF146 0.62 5.38 0.44 3.5e-7 Breast cancer; TGCT cis rs9318086 0.712 rs9510917 chr13:24442846 C/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.77 8.16 0.59 3.26e-13 Myopia (pathological); TGCT cis rs1552244 1.000 rs7648104 chr3:10073311 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs17152411 1.000 rs12573033 chr10:126607803 T/G cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs6882046 0.513 rs681446 chr5:88054292 C/T cg22951263 chr5:87985283 NA 0.62 6.64 0.51 8.81e-10 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg22508957 chr16:3507546 NAT15 -0.49 -5.5 -0.44 2.08e-7 Tuberculosis; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg09704166 chr2:114031854 PAX8;LOC440839 -0.32 -4.82 -0.4 4.04e-6 Lymphocyte counts; TGCT cis rs10197940 0.624 rs10497081 chr2:152353395 T/G cg06191203 chr2:152266755 RIF1 -0.76 -7.11 -0.54 8.05e-11 Lung cancer; TGCT cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg26818010 chr10:134567672 INPP5A -0.35 -4.52 -0.38 1.42e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17376456 0.825 rs67328989 chr5:93243133 T/A cg21475434 chr5:93447410 FAM172A 0.71 4.91 0.4 2.86e-6 Diabetic retinopathy; TGCT cis rs9430161 0.579 rs11576658 chr1:11037736 C/T cg02454025 chr1:11042201 C1orf127 0.95 10.77 0.7 1.73e-19 Ewing sarcoma; TGCT cis rs7666738 0.830 rs921523 chr4:98841659 C/T cg17366294 chr4:99064904 C4orf37 0.66 6.56 0.51 1.34e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs7691433 chr4:98968118 A/T cg05340658 chr4:99064831 C4orf37 0.44 4.68 0.39 7.36e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9913156 0.793 rs55782417 chr17:4562845 G/A cg00122941 chr17:4613640 ARRB2 0.87 7.38 0.55 1.95e-11 Lymphocyte counts; TGCT cis rs6426558 0.537 rs4351610 chr1:227325245 A/G cg10327440 chr1:227177885 CDC42BPA -0.58 -6.91 -0.53 2.21e-10 Neutrophil percentage of white cells; TGCT cis rs4851266 1.000 rs11691409 chr2:100826165 T/A cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs2236918 1.000 rs1635509 chr1:242028027 C/T cg04158730 chr1:242011433 EXO1 0.52 4.59 0.38 1.07e-5 Menopause (age at onset); TGCT cis rs4665809 0.838 rs6546780 chr2:26352857 T/C cg04944784 chr2:26401820 FAM59B -0.67 -6.04 -0.48 1.63e-8 Gut microbiome composition (summer); TGCT cis rs12477438 0.798 rs10167015 chr2:99570707 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.65 -5.62 -0.45 1.19e-7 Chronic sinus infection; TGCT cis rs35306767 0.903 rs12249828 chr10:894838 C/T cg20503657 chr10:835505 NA 0.71 9.59 0.65 1.25e-16 Eosinophil percentage of granulocytes; TGCT cis rs8038465 1.000 rs8041181 chr15:73982336 C/T cg15420318 chr15:73925796 NPTN 0.69 6.42 0.5 2.6e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11677416 1.000 rs2071375 chr2:113535438 C/T cg27083787 chr2:113543245 IL1A 0.17 4.46 0.37 1.85e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs75686122 0.881 rs116856209 chr8:104719961 T/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs10992471 0.580 rs4744143 chr9:95438627 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -4.59 -0.38 1.07e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12142240 0.698 rs17361812 chr1:46814008 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT trans rs1814175 0.791 rs11040513 chr11:49778153 G/C cg11707556 chr5:10655725 ANKRD33B -0.38 -7.76 -0.57 2.75e-12 Height; TGCT cis rs910316 1.000 rs3742778 chr14:75538217 A/C cg11812906 chr14:75593930 NEK9 -0.74 -7.31 -0.55 2.84e-11 Height; TGCT cis rs6519955 0.866 rs9626920 chr22:46428993 A/G cg11242978 chr22:46423387 NA -0.5 -4.54 -0.38 1.33e-5 Dupuytren's disease; TGCT cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg06418219 chr1:154948305 SHC1;CKS1B 0.7 7.04 0.53 1.14e-10 Prostate cancer; TGCT cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg04389838 chr3:44770851 ZNF501 -0.41 -5.69 -0.46 8.61e-8 Depressive symptoms; TGCT cis rs28785552 0.769 rs11669363 chr19:53232321 C/A cg10871876 chr19:53194124 ZNF83 0.49 6.66 0.51 7.95e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs986417 0.818 rs7144656 chr14:61032909 A/G cg27398547 chr14:60952738 C14orf39 1.49 10.43 0.68 1.12e-18 Gut microbiota (bacterial taxa); TGCT cis rs78487399 0.908 rs6726404 chr2:43834163 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 -0.65 -4.56 -0.38 1.2e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6450176 0.909 rs255755 chr5:53307772 A/G ch.5.1024479R chr5:53302184 ARL15 -0.5 -4.64 -0.38 8.56e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs597539 0.652 rs559032 chr11:68710847 G/T cg21963583 chr11:68658836 MRPL21 0.36 6.0 0.47 1.99e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6687430 0.526 rs7555790 chr1:10613167 A/G cg17425144 chr1:10567563 PEX14 -0.51 -5.89 -0.47 3.35e-8 Hand grip strength; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg14893161 chr1:205819251 PM20D1 0.65 10.64 0.69 3.58e-19 Menarche (age at onset); TGCT cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg23205692 chr1:25664452 TMEM50A -0.5 -5.19 -0.42 8.32e-7 Erythrocyte sedimentation rate; TGCT cis rs9894429 0.546 rs55917554 chr17:79608776 T/C cg21028142 chr17:79581711 NPLOC4 0.29 6.02 0.48 1.85e-8 Eye color traits; TGCT cis rs9549367 0.713 rs2476319 chr13:113836519 C/T cg00898013 chr13:113819073 PROZ 0.53 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs2153535 0.580 rs4960421 chr6:8459292 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs17253792 0.731 rs3736876 chr14:56120178 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs263156 0.967 rs263103 chr6:142875692 C/G cg18419694 chr6:143832440 FUCA2 -0.38 -4.53 -0.38 1.36e-5 Ear morphology;Lobe size;Lobe attachment; TGCT trans rs629535 0.821 rs497398 chr8:70037434 A/T cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs4319547 0.956 rs10847179 chr12:123040985 T/C cg23029597 chr12:123009494 RSRC2 -0.31 -5.09 -0.42 1.32e-6 Body mass index; TGCT cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg17971929 chr21:40555470 PSMG1 -0.7 -6.32 -0.49 4.38e-9 Cognitive function; TGCT cis rs939658 0.805 rs11630571 chr15:79432992 C/A cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs704795 0.836 rs1647281 chr2:27612938 G/C cg12000995 chr2:27665139 KRTCAP3 -0.37 -4.58 -0.38 1.11e-5 Menopause (age at onset); TGCT cis rs36051895 0.672 rs12353218 chr9:5162828 T/C cg02405213 chr9:5042618 JAK2 -0.75 -9.83 -0.66 3.25e-17 Pediatric autoimmune diseases; TGCT cis rs10465746 0.747 rs34155960 chr1:84447539 T/G cg10977910 chr1:84465055 TTLL7 0.69 7.04 0.53 1.14e-10 Obesity-related traits; TGCT cis rs9372498 0.536 rs28605789 chr6:118889952 G/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.04 -0.41 1.59e-6 Diastolic blood pressure; TGCT cis rs6558530 0.965 rs730377 chr8:1707951 G/A cg09410841 chr8:1729607 CLN8 0.91 10.31 0.68 2.23e-18 Systolic blood pressure; TGCT cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg08439880 chr3:133502540 NA -0.29 -5.42 -0.44 2.93e-7 Iron status biomarkers; TGCT cis rs28595532 0.920 rs17258050 chr4:119672019 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.54 0.38 1.34e-5 Cannabis dependence symptom count; TGCT cis rs933688 1.000 rs11950530 chr5:90688740 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.05 0.59 5.84e-13 Smoking behavior; TGCT cis rs8037137 0.915 rs79548680 chr15:91505779 G/C cg22570213 chr15:91497863 RCCD1 0.52 4.84 0.4 3.85e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs7267979 1.000 rs2258884 chr20:25279539 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.686 rs857875 chr6:145980033 T/G cg13319975 chr6:146136371 FBXO30 0.53 4.9 0.4 2.91e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3540 0.960 rs10083661 chr15:91022339 G/A cg22089800 chr15:90895588 ZNF774 0.74 6.91 0.53 2.27e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs6840360 0.642 rs2034061 chr4:152420756 C/T cg17479576 chr4:152424074 FAM160A1 -0.57 -6.02 -0.48 1.85e-8 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.903 rs11253504 chr10:956046 A/G cg20503657 chr10:835505 NA 0.74 10.28 0.68 2.58e-18 Eosinophil percentage of granulocytes; TGCT cis rs478304 0.651 rs11537193 chr11:65500003 A/C cg10518572 chr11:65560635 OVOL1 -0.24 -4.68 -0.39 7.53e-6 Acne (severe); TGCT cis rs425277 0.606 rs377283 chr1:2075570 T/C cg24578937 chr1:2090814 PRKCZ 0.25 6.22 0.49 7.12e-9 Height; TGCT cis rs7681440 0.967 rs1372517 chr4:90755909 G/A cg20003494 chr4:90757398 SNCA -0.56 -5.33 -0.43 4.56e-7 Dementia with Lewy bodies; TGCT cis rs2237234 0.848 rs2237235 chr6:26391395 A/G cg16898833 chr6:26189333 HIST1H4D 0.77 5.2 0.42 7.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2549003 1.000 rs6873426 chr5:131818631 G/T cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs7772486 0.566 rs735536 chr6:146036832 A/C cg05347473 chr6:146136440 FBXO30 -0.49 -4.62 -0.38 9.3e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 1.000 rs11947857 chr4:17691047 T/C cg18681998 chr4:17616180 MED28 -0.88 -8.45 -0.6 6.46e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1075265 0.870 rs6724389 chr2:54212835 G/A cg15001959 chr2:54483431 TSPYL6;ACYP2 -0.18 -4.63 -0.38 9.12e-6 Morning vs. evening chronotype;Chronotype; TGCT cis rs10493773 0.674 rs414618 chr1:86220418 G/A cg17807903 chr1:86174739 ZNHIT6 0.4 5.64 0.45 1.09e-7 Urate levels in overweight individuals; TGCT cis rs7172809 0.573 rs4886864 chr15:77674022 C/T cg22256960 chr15:77711686 NA -0.51 -4.79 -0.4 4.65e-6 Glucose homeostasis traits; TGCT cis rs6500602 0.702 rs4786511 chr16:4571645 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.95 0.47 2.54e-8 Schizophrenia; TGCT cis rs9952991 0.943 rs9952753 chr18:12780463 A/C cg23544223 chr18:12777786 NA 0.63 6.02 0.48 1.85e-8 Inflammatory skin disease; TGCT cis rs36051895 0.695 rs10974916 chr9:5017350 G/A cg02405213 chr9:5042618 JAK2 -0.75 -9.96 -0.67 1.62e-17 Pediatric autoimmune diseases; TGCT cis rs2288884 0.748 rs10424368 chr19:52600350 G/A cg13540795 chr19:52551618 ZNF432 -0.7 -6.03 -0.48 1.78e-8 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs2180341 0.618 rs11154396 chr6:127638911 C/T cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs9303401 0.659 rs62083368 chr17:56878062 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg06896619 chr17:61851486 DDX42;CCDC47 0.49 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs7267979 1.000 rs6083862 chr20:25411086 A/T cg16686733 chr20:25566563 NINL -0.57 -5.89 -0.47 3.34e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7659604 0.676 rs6855269 chr4:122697418 T/G cg06713675 chr4:122721982 EXOSC9 -0.62 -8.39 -0.6 9.07e-14 Type 2 diabetes; TGCT cis rs9811920 0.609 rs9817005 chr3:99682692 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.62 6.98 0.53 1.6e-10 Axial length; TGCT cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs763014 0.865 rs4006748 chr16:632225 T/C cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg06753367 chr22:24256600 NA -0.24 -4.6 -0.38 1.04e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2303759 0.881 rs10412811 chr19:49884495 G/A cg22307029 chr19:49891270 CCDC155 0.54 5.06 0.41 1.49e-6 Multiple sclerosis; TGCT cis rs1371867 0.726 rs1660333 chr8:101309989 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.5 -0.5 1.74e-9 Atrioventricular conduction; TGCT cis rs372883 0.648 rs2832297 chr21:30742996 A/C cg24692254 chr21:30365293 RNF160 0.49 4.44 0.37 1.95e-5 Pancreatic cancer; TGCT cis rs9926296 0.542 rs12599531 chr16:89909401 C/T cg27121462 chr16:89883253 FANCA -0.56 -4.93 -0.4 2.56e-6 Vitiligo; TGCT cis rs12902680 0.739 rs1402117 chr15:46391419 A/G cg13605988 chr15:45421612 DUOX1;DUOXA1 0.32 4.5 0.37 1.56e-5 Neuroticism; TGCT cis rs950169 0.840 rs35522895 chr15:84928049 G/A cg11189052 chr15:85197271 WDR73 0.81 6.46 0.5 2.14e-9 Schizophrenia; TGCT trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg22433210 chr17:43662623 NA 1.06 7.26 0.55 3.82e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7819412 0.775 rs11773990 chr8:10935082 T/C cg21775007 chr8:11205619 TDH -0.5 -4.61 -0.38 9.74e-6 Triglycerides; TGCT cis rs2439831 1.000 rs2439841 chr15:43734749 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs56399783 0.614 rs116929101 chr7:2760325 G/A cg19731401 chr7:2775893 GNA12 0.39 5.36 0.43 3.88e-7 Childhood ear infection; TGCT cis rs73198271 0.710 rs7837843 chr8:8656485 A/G cg06671706 chr8:8559999 CLDN23 -0.36 -4.52 -0.38 1.42e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs66561647 0.853 rs66824612 chr8:128967819 C/T cg11792826 chr8:129160931 MIR1208 0.23 5.07 0.41 1.41e-6 Hemoglobin concentration; TGCT cis rs7572733 0.534 rs7557203 chr2:198795650 A/G cg00792783 chr2:198669748 PLCL1 0.57 5.14 0.42 1.03e-6 Dermatomyositis; TGCT cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg07424592 chr7:64974309 NA -1.26 -7.3 -0.55 2.99e-11 Diabetic kidney disease; TGCT cis rs7000551 0.715 rs1879793 chr8:22313986 G/A cg12081754 chr8:22256438 SLC39A14 0.32 5.31 0.43 4.96e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6011674 1.000 rs6011674 chr20:61854452 A/G cg06763829 chr20:61885236 FLJ16779;NKAIN4 -0.79 -4.44 -0.37 1.99e-5 Response to cytadine analogues (cytosine arabinoside); TGCT cis rs9611565 0.559 rs13056262 chr22:42081921 A/G cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Vitiligo; TGCT cis rs6500602 0.702 rs3761680 chr16:4524060 C/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.29 5.36 0.43 3.83e-7 Schizophrenia; TGCT cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.66 6.52 0.51 1.58e-9 Bipolar disorder; TGCT cis rs28595532 0.920 rs115994609 chr4:119777273 G/A cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs4746818 1.000 rs10762263 chr10:70970178 A/G cg11621586 chr10:70884670 VPS26A 1.22 10.53 0.69 6.48e-19 Left atrial antero-posterior diameter; TGCT cis rs11249608 0.548 rs6601007 chr5:178455796 G/C cg23951258 chr5:178450506 ZNF879 0.44 4.54 0.38 1.32e-5 Pubertal anthropometrics; TGCT cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg00786635 chr1:25594202 NA 0.59 6.07 0.48 1.46e-8 Erythrocyte sedimentation rate; TGCT cis rs6671200 0.607 rs1927043 chr1:95667251 G/A cg03123541 chr1:95699097 RWDD3 -0.82 -7.07 -0.54 1.01e-10 Stearic acid (18:0) levels; TGCT cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs208520 0.690 rs6929762 chr6:66709277 C/T cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs9513593 1.000 rs9585040 chr13:100015539 T/C cg21788972 chr13:99853209 UBAC2 0.59 4.54 0.38 1.3e-5 Psoriasis; TGCT trans rs6089829 0.962 rs4586690 chr20:61658595 G/T cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs6570726 0.935 rs399169 chr6:145836353 C/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7614311 0.636 rs73117041 chr3:63896266 A/T cg22134162 chr3:63841271 THOC7 -0.4 -5.16 -0.42 9.41e-7 Lung function (FVC);Lung function (FEV1); TGCT cis rs7552404 0.727 rs2172507 chr1:76331320 A/G cg10523679 chr1:76189770 ACADM -0.68 -6.25 -0.49 6.17e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1670533 0.818 rs643484 chr4:1085826 A/G cg27284194 chr4:1044797 NA 0.68 5.95 0.47 2.59e-8 Recombination rate (females); TGCT cis rs793571 0.500 rs2555356 chr15:59016431 T/G cg05156742 chr15:59063176 FAM63B 0.47 4.46 0.37 1.78e-5 Schizophrenia; TGCT cis rs1371867 0.875 rs7830342 chr8:101327738 T/A cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs7647973 0.626 rs1586827 chr3:49671224 T/C cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs6463523 0.933 rs6974151 chr7:758269 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.74 10.63 0.69 3.74e-19 Subjective well-being; TGCT cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs9549367 0.577 rs513479 chr13:113815200 C/T cg00898013 chr13:113819073 PROZ -0.56 -6.86 -0.52 2.88e-10 Platelet distribution width; TGCT cis rs6088590 0.965 rs6087619 chr20:33288511 C/G cg08999081 chr20:33150536 PIGU 0.27 4.82 0.4 4.18e-6 Coronary artery disease; TGCT cis rs968451 0.526 rs5757617 chr22:39722714 G/C cg01093212 chr22:39715156 SNORD43;RPL3 0.5 4.66 0.39 8.12e-6 Primary biliary cholangitis; TGCT cis rs8014204 0.819 rs2003490 chr14:75377555 C/A cg06637938 chr14:75390232 RPS6KL1 0.81 7.79 0.57 2.31e-12 Caffeine consumption; TGCT cis rs2795502 0.935 rs2744060 chr10:43262616 C/G cg20628663 chr10:43360327 NA -0.41 -4.84 -0.4 3.8e-6 Blood protein levels; TGCT cis rs892961 0.932 rs7222170 chr17:75413096 G/A cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs10992471 0.598 rs1175788 chr9:95117798 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.63 -6.09 -0.48 1.29e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs875971 0.928 rs6970357 chr7:65968878 T/C cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs17711722 0.585 rs6942660 chr7:65302406 C/T cg00343986 chr7:65444356 GUSB 0.26 6.14 0.48 1.02e-8 Calcium levels; TGCT cis rs13191362 0.808 rs13217502 chr6:163231414 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.66 4.63 0.38 9.26e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10028773 0.506 rs12374346 chr4:120281705 G/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Educational attainment; TGCT cis rs36051895 0.664 rs4593605 chr9:5107278 C/A cg02405213 chr9:5042618 JAK2 -0.71 -9.43 -0.65 3.07e-16 Pediatric autoimmune diseases; TGCT cis rs6912958 0.500 rs9342104 chr6:87798512 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.73 -7.35 -0.55 2.37e-11 Monocyte percentage of white cells; TGCT cis rs559406 0.623 rs2852151 chr18:12841176 G/A cg23598886 chr18:12777645 NA 0.38 4.54 0.38 1.32e-5 Psoriasis; TGCT cis rs9916302 0.904 rs6503503 chr17:37514373 G/A cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs854765 0.520 rs9899355 chr17:17898243 C/T cg04398451 chr17:18023971 MYO15A -0.3 -4.61 -0.38 1e-5 Total body bone mineral density; TGCT trans rs11088226 0.681 rs11702499 chr21:33938565 C/T cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT trans rs561341 1.000 rs113676348 chr17:30244327 A/G cg20587970 chr11:113659929 NA -0.97 -11.61 -0.72 1.49e-21 Hip circumference adjusted for BMI; TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs8077577 0.945 rs62073608 chr17:18071448 T/C cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs2430307 0.518 rs67763033 chr7:76517677 A/G cg15770687 chr7:76625569 PMS2L11 0.34 4.53 0.38 1.37e-5 Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; TGCT cis rs2019137 0.560 rs10206269 chr2:113990393 C/A cg23156509 chr2:114033830 PAX8;LOC440839 -0.3 -4.61 -0.38 9.92e-6 Lymphocyte counts; TGCT cis rs9859260 0.744 rs406271 chr3:195776976 T/C cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs4819052 1.000 rs13053002 chr21:46677854 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.98 8.11 0.59 4.13e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs624899 0.522 rs645584 chr19:11612466 A/G cg12854483 chr19:11649671 CNN1 0.52 5.7 0.46 8.4e-8 Presence of antiphospholipid antibodies; TGCT cis rs9659323 1.000 rs9658899 chr1:119504543 G/A cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.4e-6 Body mass index; TGCT cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.520 rs36071868 chr2:99737120 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.22 0.85 7.28e-37 Chronic sinus infection; TGCT cis rs57994353 0.600 rs11145974 chr9:139316744 A/G cg13741927 chr9:139327495 INPP5E 0.25 5.74 0.46 7.02e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2594989 0.677 rs7631716 chr3:11576689 T/C cg00170343 chr3:11313890 ATG7 -0.67 -5.24 -0.43 6.68e-7 Circulating chemerin levels; TGCT cis rs9291683 0.527 rs3822241 chr4:10094931 G/A cg00071950 chr4:10020882 SLC2A9 -0.54 -5.74 -0.46 6.75e-8 Bone mineral density; TGCT cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg00786635 chr1:25594202 NA 0.59 6.28 0.49 5.23e-9 Plateletcrit;Mean corpuscular volume; TGCT cis rs921968 0.643 rs2178019 chr2:219316303 G/A cg02176678 chr2:219576539 TTLL4 0.37 5.45 0.44 2.58e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7226408 0.857 rs8098708 chr18:34563373 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs3751972 0.911 rs2079714 chr17:26222520 C/T cg02948944 chr17:26242737 NA 0.49 7.07 0.54 1.02e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs1697139 0.583 rs11739603 chr5:66540687 C/T cg11553311 chr5:66541588 NA 0.28 6.02 0.48 1.82e-8 Breast cancer; TGCT cis rs7666738 0.830 rs11097609 chr4:99011707 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2456568 0.606 rs11020616 chr11:93691594 C/T cg26875233 chr11:93583750 C11orf90 0.43 5.18 0.42 8.54e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg24503407 chr1:205819492 PM20D1 0.6 8.49 0.61 5.35e-14 Menarche (age at onset); TGCT cis rs9611565 0.649 rs126092 chr22:42178441 A/G cg06634786 chr22:41940651 POLR3H 0.83 7.61 0.56 6.08e-12 Vitiligo; TGCT cis rs7524258 0.900 rs7514988 chr1:7271651 C/T cg07173049 chr1:7289937 CAMTA1 0.29 4.68 0.39 7.35e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs6840360 0.967 rs6832562 chr4:152602798 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.65 -0.45 1.03e-7 Intelligence (multi-trait analysis); TGCT cis rs892961 1.000 rs11077909 chr17:75403480 T/C cg05865280 chr17:75406074 SEPT9 0.27 6.67 0.51 7.74e-10 Airflow obstruction; TGCT cis rs902774 0.554 rs4919749 chr12:53358034 C/T cg05393297 chr12:53359155 NA -0.75 -8.54 -0.61 3.99e-14 Prostate cancer; TGCT cis rs4808199 0.895 rs10419672 chr19:19471241 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.73 5.84 0.46 4.35e-8 Nonalcoholic fatty liver disease; TGCT cis rs8014204 0.533 rs12434646 chr14:75178693 C/T cg06637938 chr14:75390232 RPS6KL1 0.61 5.51 0.44 1.98e-7 Caffeine consumption; TGCT cis rs4665809 1.000 rs6750681 chr2:26329677 C/T cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT trans rs10506458 0.915 rs998506 chr12:63400017 C/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs9902453 1.000 rs12600855 chr17:28279591 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 6.61 0.51 1.01e-9 Coffee consumption (cups per day); TGCT cis rs2816062 0.786 rs2745320 chr1:18893592 G/A cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs2997447 0.761 rs74384164 chr1:26430379 C/T cg03844060 chr1:26490628 NA 0.28 4.6 0.38 1.04e-5 QRS complex (12-leadsum); TGCT cis rs709400 0.663 rs72710714 chr14:103981849 T/G cg12935359 chr14:103987150 CKB -0.39 -5.76 -0.46 6.29e-8 Body mass index; TGCT cis rs968567 0.539 rs174556 chr11:61580635 C/T cg01500311 chr11:61656094 FADS3 -0.29 -4.98 -0.41 2.1e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs10883723 0.773 rs1326193 chr10:104271674 G/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6545883 0.965 rs3771261 chr2:61762161 A/G cg15711740 chr2:61764176 XPO1 -0.57 -5.29 -0.43 5.32e-7 Tuberculosis; TGCT cis rs13191362 1.000 rs13209100 chr6:163159350 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.84 7.84 0.58 1.75e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9926296 0.605 rs12448860 chr16:89849629 T/A cg26513180 chr16:89883248 FANCA 1.07 14.76 0.8 4.4e-29 Vitiligo; TGCT cis rs7267979 0.604 rs242130 chr20:25594020 C/A cg16686733 chr20:25566563 NINL -0.51 -4.92 -0.4 2.66e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7552404 1.000 rs211723 chr1:76103030 C/T cg10523679 chr1:76189770 ACADM -0.93 -10.08 -0.67 8.31e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17293817 0.650 rs12778422 chr10:1413776 A/G cg27336261 chr10:1975562 NA 0.35 4.91 0.4 2.84e-6 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4919694 1.000 rs11191473 chr10:104710710 C/G cg04362960 chr10:104952993 NT5C2 1.07 7.15 0.54 6.49e-11 Arsenic metabolism; TGCT cis rs1215050 0.527 rs1214998 chr4:99042878 T/G cg05340658 chr4:99064831 C4orf37 0.44 5.35 0.43 4.12e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2594989 0.836 rs347609 chr3:11269999 G/C cg00170343 chr3:11313890 ATG7 0.66 4.56 0.38 1.2e-5 Circulating chemerin levels; TGCT cis rs11214589 0.774 rs10891544 chr11:113256152 A/C cg14159747 chr11:113255604 NA -0.4 -4.93 -0.41 2.54e-6 Neuroticism; TGCT cis rs6964587 0.967 rs2299235 chr7:91627500 C/T cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs4665809 1.000 rs2384322 chr2:26291146 C/G cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs2070488 0.662 rs6599202 chr3:38480651 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.72 5.94 0.47 2.7e-8 Electrocardiographic conduction measures; TGCT cis rs3771570 1.000 rs56383420 chr2:242219281 A/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs35306767 0.951 rs12777021 chr10:967270 T/C cg26597838 chr10:835615 NA 0.71 10.24 0.68 3.36e-18 Eosinophil percentage of granulocytes; TGCT cis rs1577917 1.000 rs10944170 chr6:86685469 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs2281845 0.965 rs3738262 chr1:201083343 A/G cg22815214 chr1:201083145 CACNA1S 0.25 4.66 0.39 7.93e-6 Permanent tooth development; TGCT cis rs968451 0.951 rs12627838 chr22:39733521 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.92 8.97 0.63 3.87e-15 Primary biliary cholangitis; TGCT cis rs2456568 0.803 rs10831141 chr11:93640728 C/T cg14065697 chr11:93583672 C11orf90 -0.37 -4.46 -0.37 1.84e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7226408 0.901 rs17652953 chr18:34761705 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs10504229 1.000 rs76944716 chr8:58191643 T/C cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs6933660 0.800 rs13201167 chr6:151773504 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.55 5.23 0.43 6.98e-7 Menarche (age at onset); TGCT cis rs8017423 0.740 rs8003095 chr14:90680643 A/T cg04374321 chr14:90722782 PSMC1 0.77 7.94 0.58 1.06e-12 Mortality in heart failure; TGCT cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs2299587 0.642 rs2073570 chr8:17782627 C/G cg01800426 chr8:17659068 MTUS1 -0.64 -5.55 -0.45 1.66e-7 Economic and political preferences; TGCT cis rs4455778 0.580 rs7803736 chr7:49125011 A/G cg26309511 chr7:48887640 NA 0.51 6.62 0.51 9.97e-10 Lung cancer in never smokers; TGCT cis rs35934224 0.771 rs34820460 chr22:19869210 G/A cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.03e-7 Glaucoma (primary open-angle); TGCT cis rs67311347 1.000 rs9822644 chr3:40426609 G/A cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs2120019 0.567 rs12385940 chr15:75168162 C/T cg09165964 chr15:75287851 SCAMP5 -0.84 -6.58 -0.51 1.19e-9 Blood trace element (Zn levels); TGCT trans rs4332037 0.713 rs56093134 chr7:1973970 C/T cg25206134 chr2:45395956 NA 0.99 7.94 0.58 1.06e-12 Bipolar disorder; TGCT cis rs8030485 0.536 rs4778918 chr15:79434040 T/C cg17916960 chr15:79447300 NA 0.39 5.87 0.47 3.66e-8 Left ventricle wall thickness; TGCT cis rs737008 0.922 rs2070923 chr16:11369855 G/T cg00044050 chr16:11439710 C16orf75 0.72 7.35 0.55 2.29e-11 Obesity-related traits; TGCT cis rs7666738 0.830 rs10001702 chr4:99065160 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs4323111 chr4:98952276 A/G cg18180107 chr4:99064573 C4orf37 0.55 4.98 0.41 2.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 0.904 rs10853136 chr17:28406018 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.82 -7.84 -0.58 1.77e-12 Coffee consumption (cups per day); TGCT cis rs7811142 0.720 rs7795656 chr7:99950297 A/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.5 4.7 0.39 6.87e-6 Colorectal cancer; TGCT cis rs3733585 0.631 rs7699671 chr4:10125874 C/T cg11266682 chr4:10021025 SLC2A9 -0.53 -6.17 -0.48 8.79e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs986417 0.818 rs12880313 chr14:60935504 T/C cg27398547 chr14:60952738 C14orf39 1.42 8.68 0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs13108904 0.818 rs3775099 chr4:1232510 C/G cg05665937 chr4:1216051 CTBP1 0.24 4.69 0.39 7.09e-6 Obesity-related traits; TGCT cis rs1903068 0.785 rs10020668 chr4:55996903 C/T cg16572876 chr4:56024045 NA 0.42 4.78 0.39 4.89e-6 Endometriosis; TGCT cis rs1670533 1.000 rs1670534 chr4:1087265 T/C cg20887711 chr4:1340912 KIAA1530 0.66 5.33 0.43 4.49e-7 Recombination rate (females); TGCT cis rs2204008 0.715 rs12368462 chr12:38336116 C/G cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs936229 0.798 rs1869959 chr15:75147332 A/C cg10253484 chr15:75165896 SCAMP2 -0.79 -6.98 -0.53 1.57e-10 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs2153535 0.553 rs2984099 chr6:8637274 C/T cg07606381 chr6:8435919 SLC35B3 -0.75 -5.91 -0.47 3.09e-8 Motion sickness; TGCT cis rs7264396 0.690 rs2425175 chr20:34445563 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs9381040 0.655 rs2268192 chr6:41024626 T/C cg03526776 chr6:41159608 TREML2 0.27 5.29 0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs6831352 0.703 rs3133152 chr4:100031721 C/G cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs210138 1.000 rs210137 chr6:33542478 C/T cg07679836 chr6:33548423 BAK1 0.39 5.34 0.43 4.28e-7 Testicular germ cell tumor; TGCT cis rs8042680 0.554 rs2301826 chr15:91525197 A/G cg22570213 chr15:91497863 RCCD1 -0.42 -4.44 -0.37 1.94e-5 Type 2 diabetes; TGCT cis rs533581 0.866 rs561795 chr16:88970818 A/G cg16701003 chr16:89028210 CBFA2T3 0.38 5.12 0.42 1.15e-6 Social autistic-like traits; TGCT cis rs748404 0.660 rs548704 chr15:43791706 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.71 0.39 6.47e-6 Lung cancer; TGCT cis rs9611519 0.531 rs1967708 chr22:41444444 G/C cg13695892 chr22:41940480 POLR3H -0.58 -5.57 -0.45 1.48e-7 Neuroticism; TGCT cis rs17102423 0.594 rs2781374 chr14:65568563 C/T cg11161011 chr14:65562177 MAX -0.47 -6.44 -0.5 2.41e-9 Obesity-related traits; TGCT cis rs6163 0.588 rs12763284 chr10:104508202 C/T cg05855489 chr10:104503620 C10orf26 -1.0 -12.58 -0.75 6.74e-24 Waist circumference;Hip circumference; TGCT cis rs13108904 0.870 rs3755924 chr4:1238363 A/G cg03303774 chr4:1407052 NA 0.28 4.57 0.38 1.16e-5 Obesity-related traits; TGCT cis rs9394841 0.667 rs9394831 chr6:41753084 C/T cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs7267979 0.764 rs2474767 chr20:25246733 T/C cg16686733 chr20:25566563 NINL 0.51 5.1 0.42 1.22e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2172802 1.000 rs10866123 chr4:62455828 A/G cg04118610 chr4:62707027 LPHN3 -0.42 -4.9 -0.4 2.9e-6 Partial epilepsies; TGCT cis rs1577917 0.958 rs11754330 chr6:86455070 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.81e-7 Response to antipsychotic treatment; TGCT cis rs9796 0.553 rs7171437 chr15:41315168 G/A cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.72 -0.52 5.97e-10 Menopause (age at onset); TGCT cis rs1018836 0.773 rs7837109 chr8:91639178 C/T cg16814680 chr8:91681699 NA -0.81 -8.71 -0.62 1.59e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs908922 0.676 rs498184 chr1:152501423 G/C cg20991723 chr1:152506922 NA 0.46 6.24 0.49 6.32e-9 Hair morphology; TGCT cis rs9302001 0.883 rs1407893 chr13:95457203 A/G cg07483244 chr13:95358924 NA 0.35 4.45 0.37 1.92e-5 Panic disorder; TGCT cis rs1018836 0.892 rs2187981 chr8:91549629 T/C cg16814680 chr8:91681699 NA -0.77 -8.15 -0.59 3.43e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.830 rs13129503 chr4:98987892 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs2692947 0.644 rs1168976 chr2:96813480 G/A cg22654517 chr2:96458247 NA 0.23 4.86 0.4 3.42e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7412746 0.611 rs10888398 chr1:150886782 A/G cg04414720 chr1:150670196 GOLPH3L -0.37 -4.46 -0.37 1.81e-5 Melanoma; TGCT cis rs17345786 0.906 rs72944107 chr3:101197190 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs7954584 0.567 rs11043246 chr12:122368944 G/A cg22618164 chr12:122356400 WDR66 0.68 6.47 0.5 2.09e-9 Mean corpuscular volume; TGCT cis rs2303759 0.918 rs2288480 chr19:49867016 C/G cg22307029 chr19:49891270 CCDC155 0.56 5.28 0.43 5.56e-7 Multiple sclerosis; TGCT cis rs60843830 0.623 rs55932737 chr2:107543 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.62 5.47 0.44 2.43e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7917772 0.503 rs11191325 chr10:104302933 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2354432 0.505 rs72691009 chr1:146708397 C/T cg25205988 chr1:146714368 CHD1L -1.15 -4.8 -0.4 4.49e-6 Mitochondrial DNA levels; TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg19536664 chr17:6899085 ALOX12 0.38 6.04 0.48 1.68e-8 Tonsillectomy; TGCT cis rs6728642 1.000 rs75297860 chr2:97600078 G/A cg26665480 chr2:98280029 ACTR1B -0.97 -5.3 -0.43 5.13e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs33794 0.901 rs33778 chr3:45287918 A/G cg18645101 chr3:44551900 NA 0.55 4.82 0.4 4.08e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs7100689 0.577 rs9285726 chr10:82035150 A/T cg01528321 chr10:82214614 TSPAN14 0.7 6.78 0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs8072100 0.576 rs7216112 chr17:45406345 C/T cg08085267 chr17:45401833 C17orf57 0.53 5.58 0.45 1.45e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs72945132 0.825 rs58532402 chr11:70189491 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT trans rs1005277 0.579 rs2505240 chr10:38442419 G/T cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.5e-21 Extrinsic epigenetic age acceleration; TGCT cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg26531700 chr6:26746687 NA -0.7 -6.84 -0.52 3.25e-10 Schizophrenia; TGCT cis rs17401966 0.894 rs12141201 chr1:10454714 G/A cg19773385 chr1:10388646 KIF1B -0.23 -5.42 -0.44 2.97e-7 Hepatocellular carcinoma; TGCT cis rs4319547 0.695 rs4758648 chr12:122900460 A/G cg05707623 chr12:122985044 ZCCHC8 -0.63 -5.01 -0.41 1.87e-6 Body mass index; TGCT cis rs12950390 0.853 rs12451815 chr17:45855956 A/G cg24803719 chr17:45855879 NA -0.44 -4.48 -0.37 1.7e-5 IgG glycosylation; TGCT cis rs3761847 0.651 rs1323472 chr9:123826335 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 4.52 0.38 1.42e-5 Rheumatoid arthritis; TGCT cis rs79349575 0.811 rs80032154 chr17:47014992 C/A cg26022315 chr17:47021804 SNF8 0.52 5.17 0.42 9.24e-7 Type 2 diabetes; TGCT trans rs1499614 1.000 rs1267818 chr7:66107024 C/T cg07424592 chr7:64974309 NA 1.31 7.65 0.57 4.73e-12 Gout; TGCT cis rs1062177 1.000 rs62377945 chr5:151208004 C/G cg00977110 chr5:151150581 G3BP1 0.4 4.52 0.38 1.4e-5 Preschool internalizing problems; TGCT cis rs7773004 0.905 rs994379 chr6:26305407 C/G cg13569146 chr6:26330589 NA 0.48 4.57 0.38 1.17e-5 Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour); TGCT cis rs12541335 0.639 rs3923439 chr8:22170079 G/A cg07298985 chr8:22133076 PIWIL2 0.33 5.25 0.43 6.3e-7 Hypertriglyceridemia; TGCT cis rs9611565 0.568 rs2413656 chr22:42129357 G/T cg03806693 chr22:41940476 POLR3H 0.94 9.16 0.64 1.35e-15 Vitiligo; TGCT cis rs9303401 0.659 rs12946852 chr17:57013337 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.16 0.48 9.11e-9 Cognitive test performance; TGCT cis rs228437 0.586 rs12663941 chr6:134916963 A/G cg09872934 chr6:134495829 SGK1 0.53 4.55 0.38 1.24e-5 Melanoma; TGCT cis rs904251 0.504 rs9380677 chr6:37480366 A/G cg08126542 chr6:37504118 NA -0.46 -6.69 -0.51 6.9e-10 Cognitive performance; TGCT cis rs8014204 0.804 rs2287403 chr14:75259140 C/T cg06637938 chr14:75390232 RPS6KL1 0.7 6.77 0.52 4.47e-10 Caffeine consumption; TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg25767906 chr1:53392781 SCP2 -0.5 -5.97 -0.47 2.29e-8 Monocyte count; TGCT cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg22029157 chr1:209979665 IRF6 0.76 6.32 0.49 4.37e-9 Cleft lip with or without cleft palate; TGCT cis rs9372498 0.536 rs9489452 chr6:118910868 G/C cg07617317 chr6:118971624 C6orf204 0.49 5.22 0.42 7.37e-7 Diastolic blood pressure; TGCT cis rs11677416 0.961 rs3783557 chr2:113530712 C/T cg27083787 chr2:113543245 IL1A 0.18 4.46 0.37 1.84e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs904251 0.861 rs2776875 chr6:37486796 G/C cg08126542 chr6:37504118 NA -0.44 -5.92 -0.47 2.96e-8 Cognitive performance; TGCT cis rs7223966 1.000 rs9893348 chr17:61676534 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.69 0.39 7.19e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg03452623 chr4:187889614 NA -0.36 -5.3 -0.43 5.01e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs629535 0.725 rs639127 chr8:70073251 A/G cg21567404 chr3:27674614 NA 0.57 9.09 0.63 1.94e-15 Dupuytren's disease; TGCT cis rs4689388 0.853 rs13114527 chr4:6294655 T/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9814567 0.806 rs4955525 chr3:134317008 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.77 -7.13 -0.54 7.12e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6542838 0.611 rs17758170 chr2:99531842 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.54 -4.88 -0.4 3.18e-6 Fear of minor pain; TGCT cis rs4713118 0.911 rs2394000 chr6:27686991 A/G cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT cis rs6582630 0.555 rs10880612 chr12:38509427 A/G cg13010199 chr12:38710504 ALG10B 0.6 4.88 0.4 3.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs10788264 0.590 rs4237538 chr10:124063140 A/G cg09507567 chr10:124027408 NA 0.39 5.46 0.44 2.5e-7 Total body bone mineral density; TGCT cis rs2354432 0.607 rs12404113 chr1:146750343 C/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs9894429 0.646 rs12948797 chr17:79617384 G/A cg21028142 chr17:79581711 NPLOC4 0.29 5.93 0.47 2.76e-8 Eye color traits; TGCT cis rs6964587 1.000 rs11971885 chr7:91674807 T/C cg17063962 chr7:91808500 NA 0.88 9.65 0.65 8.91e-17 Breast cancer; TGCT cis rs16910800 0.689 rs4491218 chr11:23163977 G/A cg20040320 chr11:23191996 NA -0.52 -4.44 -0.37 1.96e-5 Cancer; TGCT cis rs769267 0.896 rs2315610 chr19:19597240 T/C cg03709012 chr19:19516395 GATAD2A 0.75 6.2 0.49 7.59e-9 Tonsillectomy; TGCT cis rs362296 0.511 rs2051558 chr4:3324886 G/A cg06533319 chr4:3265114 C4orf44 -0.22 -4.9 -0.4 2.99e-6 Parental longevity (mother's age at death); TGCT cis rs34526934 0.524 rs1124052 chr2:177040084 G/A cg26754761 chr2:177040938 NA -0.3 -5.6 -0.45 1.33e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs7772486 0.817 rs9322047 chr6:146400394 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs35146811 0.735 rs858506 chr7:99820050 T/C cg13334819 chr7:99746414 C7orf59 0.74 6.41 0.5 2.82e-9 Coronary artery disease; TGCT cis rs2239547 0.657 rs2071040 chr3:52864860 A/G cg11645453 chr3:52864694 ITIH4 0.34 5.59 0.45 1.39e-7 Schizophrenia; TGCT cis rs7178572 0.568 rs12910480 chr15:77664212 G/C cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.58e-6 Type 2 diabetes; TGCT cis rs2115630 0.967 rs11073702 chr15:85310071 G/A cg11189052 chr15:85197271 WDR73 -0.63 -6.04 -0.48 1.67e-8 P wave terminal force; TGCT cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs7226408 0.948 rs17652351 chr18:34393672 C/G cg06757138 chr18:34340585 FHOD3 0.26 4.7 0.39 6.74e-6 Obesity-related traits; TGCT cis rs910316 0.935 rs2268620 chr14:75640403 G/A cg11812906 chr14:75593930 NEK9 -0.74 -7.3 -0.55 3.1e-11 Height; TGCT trans rs114540395 0.858 rs117416511 chr10:103351588 G/A cg10198749 chr1:39920707 MACF1 0.55 7.03 0.53 1.2e-10 Schizophrenia; TGCT cis rs12497850 0.931 rs7431710 chr3:48935583 G/A cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs478222 1.000 rs2577277 chr2:25310247 T/C cg01884057 chr2:25150051 NA -0.26 -4.96 -0.41 2.26e-6 Type 1 diabetes; TGCT cis rs992157 0.835 rs12987219 chr2:219144149 G/A cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs6671200 1.000 rs34396223 chr1:95697828 C/T cg26537280 chr1:95699037 RWDD3 0.7 5.55 0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs7769051 0.711 rs9493435 chr6:133088205 A/G cg07930552 chr6:133119739 C6orf192 0.89 5.02 0.41 1.77e-6 Type 2 diabetes nephropathy; TGCT cis rs12479064 0.724 rs3087403 chr2:100058870 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -6.49 -0.5 1.82e-9 Chronic sinus infection; TGCT cis rs826838 0.967 rs1719854 chr12:39127707 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs7647973 0.554 rs13096480 chr3:49658084 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs6089829 0.926 rs1060489 chr20:61665921 C/T cg18188782 chr20:61659543 NA 0.46 5.55 0.45 1.61e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs12210905 0.688 rs115309746 chr6:27491562 G/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs1552244 0.882 rs13075842 chr3:10055813 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs10510102 0.872 rs7906462 chr10:123707613 C/T cg23691251 chr10:123688108 ATE1 -0.61 -4.71 -0.39 6.41e-6 Breast cancer; TGCT cis rs7666738 0.546 rs2098935 chr4:98914376 A/G cg05340658 chr4:99064831 C4orf37 0.59 6.52 0.51 1.62e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs3740393 0.562 rs60459635 chr10:104500988 T/G cg05855489 chr10:104503620 C10orf26 0.74 6.05 0.48 1.57e-8 Microalbuminuria; TGCT cis rs3764563 1.000 rs1022413 chr19:15741984 G/A cg20725493 chr19:15740067 CYP4F8 -0.43 -4.67 -0.39 7.75e-6 Inflammatory biomarkers; TGCT cis rs769267 0.929 rs2905421 chr19:19457908 G/T cg02546618 chr19:19431379 KIAA0892;SF4 0.63 5.3 0.43 5.01e-7 Tonsillectomy; TGCT cis rs6882046 0.513 rs34320 chr5:88021527 T/G cg22951263 chr5:87985283 NA -0.58 -6.18 -0.49 8.49e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT trans rs57221529 0.766 rs4957053 chr5:575927 T/C cg25482853 chr8:67687455 SGK3 1.16 10.5 0.69 7.91e-19 Lung disease severity in cystic fibrosis; TGCT cis rs6582630 0.555 rs11182422 chr12:38522833 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.75 0.57 2.85e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs7267979 0.932 rs2260997 chr20:25256266 A/C cg16686733 chr20:25566563 NINL -0.58 -6.12 -0.48 1.14e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6500602 0.727 rs4238849 chr16:4538114 G/A cg08645402 chr16:4508243 NA 0.18 5.05 0.41 1.55e-6 Schizophrenia; TGCT cis rs1475911 1.000 rs2839465 chr21:43511232 C/T cg24372256 chr21:43528868 UMODL1;C21orf128 -0.25 -4.71 -0.39 6.46e-6 IgG glycosylation; TGCT cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT trans rs1814175 0.817 rs28525029 chr11:50045815 A/G cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs769267 0.931 rs2965197 chr19:19470910 C/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.56 -4.58 -0.38 1.13e-5 Tonsillectomy; TGCT cis rs801193 1.000 rs10274773 chr7:66133578 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.13 -0.42 1.07e-6 Aortic root size; TGCT cis rs4727027 0.835 rs11767810 chr7:148774433 T/A cg23583168 chr7:148888333 NA -0.69 -8.67 -0.61 2.04e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs10791097 0.765 rs10894269 chr11:130722789 C/T cg12179176 chr11:130786555 SNX19 0.75 8.62 0.61 2.66e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3809566 0.636 rs4775604 chr15:63323880 A/C cg00520135 chr15:63333846 TPM1 -0.4 -4.72 -0.39 6.34e-6 Platelet count; TGCT cis rs116095464 0.558 rs6878087 chr5:223117 C/T cg22857025 chr5:266934 NA 0.31 6.2 0.49 7.82e-9 Breast cancer; TGCT cis rs9640161 0.750 rs55974958 chr7:150037927 C/T cg17279839 chr7:150038598 RARRES2 0.44 4.78 0.39 4.82e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs11935103 0.673 rs9997142 chr4:187297025 T/C cg16785698 chr4:186456103 PDLIM3 0.44 4.47 0.37 1.74e-5 Response to citalopram treatment; TGCT cis rs259282 0.605 rs35728696 chr19:33108096 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.52 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs7945705 0.837 rs10769981 chr11:9024460 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.05 0.41 1.56e-6 Hemoglobin concentration; TGCT cis rs2842992 0.915 rs2842958 chr6:160108425 A/G cg11366901 chr6:160182831 ACAT2 0.94 6.18 0.49 8.48e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg12419862 chr22:24373484 LOC391322 0.87 7.7 0.57 3.63e-12 S-phenylmercapturic acid levels in smokers; TGCT cis rs17253792 0.822 rs75936910 chr14:56149351 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT trans rs8073060 1.000 rs8073060 chr17:33875262 T/A cg19694781 chr19:47549865 TMEM160 0.41 7.48 0.56 1.18e-11 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1127311 1.000 rs1127311 chr1:154556663 G/A cg17218026 chr1:154582156 ADAR 0.29 7.29 0.55 3.13e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs55692411 0.537 rs13071931 chr3:50062878 G/A cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs17331151 0.541 rs1139106 chr3:52871101 G/A cg11137980 chr3:52469226 SEMA3G 0.28 4.94 0.41 2.51e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8017423 0.647 rs12895269 chr14:90822430 T/C cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs17401966 0.518 rs10864453 chr1:10407169 T/G cg19773385 chr1:10388646 KIF1B -0.22 -5.27 -0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs6570726 0.791 rs9376953 chr6:145912226 G/T cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11190604 0.767 rs10883478 chr10:102162852 C/T cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7729723 0.545 rs3910201 chr5:137812934 A/G cg19169342 chr5:137827400 NA 0.33 4.71 0.39 6.52e-6 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs6089829 0.962 rs3746747 chr20:61667631 T/C cg02380750 chr20:61661411 NA 0.33 5.82 0.46 4.76e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs9948 0.521 rs59073958 chr2:97352693 C/T cg01990225 chr2:97406019 LMAN2L -0.94 -4.74 -0.39 5.71e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs1005277 0.602 rs1780141 chr10:38504299 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2224391 0.628 rs2773309 chr6:5248916 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.98 -6.21 -0.49 7.43e-9 Height; TGCT cis rs4786125 0.665 rs6500858 chr16:6906111 T/C cg03623568 chr16:6915990 A2BP1 -0.42 -6.19 -0.49 7.91e-9 Heart rate variability traits (SDNN); TGCT cis rs55962025 1.000 rs4690071 chr4:3086753 A/T cg06533319 chr4:3265114 C4orf44 0.23 4.75 0.39 5.53e-6 Parental longevity (mother's age at death); TGCT cis rs9534288 0.797 rs9526127 chr13:46571744 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT trans rs2898290 0.694 rs2248909 chr8:11392093 A/C cg15556689 chr8:8085844 FLJ10661 -0.76 -7.1 -0.54 8.56e-11 Systolic blood pressure; TGCT cis rs9359856 0.510 rs2768940 chr6:90436319 A/G cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.66 -0.39 7.9e-6 Bipolar disorder; TGCT cis rs1524927 1.000 rs12704875 chr7:96341385 G/A cg03808172 chr7:96339361 SHFM1 0.49 5.06 0.41 1.45e-6 Total body bone mineral density; TGCT cis rs4916646 0.592 rs10030756 chr4:11517076 C/T cg16957523 chr4:11431359 HS3ST1 -0.47 -4.66 -0.39 8.08e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs797680 0.856 rs531358 chr1:93676011 C/T cg17826107 chr1:92977322 EVI5 -0.24 -5.29 -0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs11190604 0.943 rs11190588 chr10:102273565 C/T cg16342193 chr10:102329863 NA -0.44 -5.5 -0.44 2.04e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1005277 0.540 rs1987431 chr10:37988887 T/C cg25427524 chr10:38739819 LOC399744 -0.33 -6.58 -0.51 1.16e-9 Extrinsic epigenetic age acceleration; TGCT cis rs7572733 0.534 rs700684 chr2:198713099 C/T cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs2067615 0.579 rs10778502 chr12:107090201 T/C cg15890332 chr12:107067104 RFX4 0.31 6.21 0.49 7.19e-9 Heart rate; TGCT cis rs3733585 0.534 rs7375642 chr4:9955236 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs270601 0.837 rs367805 chr5:131701279 T/C cg24060327 chr5:131705240 SLC22A5 -0.77 -8.49 -0.61 5.36e-14 Acylcarnitine levels; TGCT cis rs6125597 0.967 rs6122779 chr20:47893014 T/C cg11220565 chr20:47934802 NA -0.3 -4.61 -0.38 9.8e-6 Intelligence (multi-trait analysis); TGCT cis rs9788721 0.836 rs1504550 chr15:78766250 A/G cg18825076 chr15:78729989 IREB2 -0.34 -5.12 -0.42 1.13e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg21171335 chr12:122356390 WDR66 0.63 7.03 0.53 1.24e-10 Mean corpuscular volume; TGCT cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg09904177 chr6:26538194 HMGN4 0.66 6.3 0.49 4.64e-9 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.623 rs12349113 chr9:5254224 T/A cg02405213 chr9:5042618 JAK2 -0.75 -9.51 -0.65 1.9e-16 Pediatric autoimmune diseases; TGCT cis rs2153535 0.541 rs7774752 chr6:8468978 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg10263370 chr3:44754102 ZNF502 -0.4 -4.8 -0.4 4.47e-6 Depressive symptoms; TGCT cis rs13256369 0.851 rs13266562 chr8:8564065 T/C cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs6599388 0.803 rs11248057 chr4:906131 C/G cg27636047 chr4:1581088 NA 0.42 4.63 0.38 8.94e-6 Parkinson's disease; TGCT cis rs854624 0.892 rs1734958 chr17:34336561 G/A cg02022384 chr17:34097390 MMP28 0.46 4.63 0.38 9.18e-6 Blood protein levels; TGCT cis rs10411936 0.785 rs2363120 chr19:16519871 C/A cg19006008 chr19:16999768 F2RL3 -0.27 -4.73 -0.39 5.95e-6 White blood cell count;Multiple sclerosis; TGCT cis rs7772486 0.682 rs1337840 chr6:146042558 T/C cg05347473 chr6:146136440 FBXO30 -0.5 -4.75 -0.39 5.58e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9357506 0.818 rs1345057 chr6:46306835 C/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs3892630 0.757 rs8109823 chr19:33183316 A/G cg22980127 chr19:33182716 NUDT19 0.72 5.21 0.42 7.77e-7 Red blood cell traits; TGCT cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs3820068 0.581 rs34453754 chr1:15993208 G/C cg05660106 chr1:15850417 CASP9 0.68 6.52 0.51 1.59e-9 Systolic blood pressure; TGCT cis rs11190604 1.000 rs10883509 chr10:102296461 C/T cg23241863 chr10:102295624 HIF1AN 0.71 5.37 0.43 3.67e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1008375 0.966 rs1860599 chr4:17638900 T/C cg10189774 chr4:17578691 LAP3 0.62 5.5 0.44 2.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs806215 0.950 rs3735642 chr7:127224286 A/G cg25922125 chr7:127225783 GCC1 -0.61 -6.29 -0.49 5.07e-9 Type 2 diabetes; TGCT cis rs8050907 0.744 rs8063956 chr16:4531761 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs916888 0.610 rs199446 chr17:44813169 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.58 -4.51 -0.38 1.51e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4253772 0.575 rs9615956 chr22:46749634 C/T cg24881330 chr22:46731750 TRMU 0.94 4.45 0.37 1.86e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs3806843 0.548 rs246057 chr5:140325583 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs12911832 0.727 rs2604454 chr15:59098732 C/A cg05156742 chr15:59063176 FAM63B 0.56 5.5 0.44 2.08e-7 Schizophrenia; TGCT cis rs59574136 1 rs59574136 chr7:2036460 T/C cg22963979 chr7:1858916 MAD1L1 -0.45 -7.41 -0.55 1.73e-11 Autism spectrum disorder or schizophrenia; TGCT trans rs3848445 1.000 rs7214411 chr17:14288990 C/T cg24575275 chr7:1094737 C7orf50 -0.71 -6.72 -0.52 6.03e-10 Protein quantitative trait loci; TGCT trans rs9329221 0.682 rs11786677 chr8:10264260 A/G cg15556689 chr8:8085844 FLJ10661 0.74 6.71 0.52 6.28e-10 Neuroticism; TGCT cis rs769267 0.930 rs1063966 chr19:19616742 G/A cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs1401999 1.000 rs4148579 chr3:183685249 T/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs2932538 0.961 rs2932529 chr1:113193364 G/A cg10983938 chr1:113465962 AFARP1;SLC16A1 -0.21 -4.44 -0.37 1.99e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9311474 0.508 rs17052256 chr3:52593119 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.1 -0.42 1.22e-6 Electroencephalogram traits; TGCT cis rs6089829 0.962 rs2277768 chr20:61666823 T/C cg08564027 chr20:61660810 NA 0.37 6.84 0.52 3.22e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2354432 0.607 rs57078845 chr1:146722222 G/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs10504229 0.683 rs61201557 chr8:58138370 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9831754 0.906 rs6782626 chr3:78406178 T/C cg06138941 chr3:78371609 NA -0.48 -5.2 -0.42 7.84e-7 Calcium levels; TGCT trans rs62103177 0.810 rs62103178 chr18:77624555 C/G cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs614226 1.000 rs1167726 chr12:120967364 A/C cg01236616 chr12:121019343 POP5 -1.24 -12.65 -0.75 4.55e-24 Type 1 diabetes nephropathy; TGCT cis rs7666738 0.546 rs6827131 chr4:98744810 C/G cg17366294 chr4:99064904 C4orf37 0.62 5.77 0.46 6.03e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs7975161 0.640 rs10778323 chr12:104746075 A/G cg25273343 chr12:104657179 TXNRD1 0.32 4.64 0.38 8.79e-6 Toenail selenium levels; TGCT cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg08683831 chr4:1404607 NA -0.47 -4.67 -0.39 7.72e-6 Obesity-related traits; TGCT cis rs12971120 0.891 rs4891557 chr18:72170299 C/T cg26446133 chr18:72167187 CNDP2 -0.37 -6.33 -0.49 4.13e-9 Refractive error; TGCT cis rs926938 0.527 rs7526844 chr1:115543759 T/C cg12756093 chr1:115239321 AMPD1 0.35 5.09 0.42 1.3e-6 Autism; TGCT cis rs921968 0.643 rs563268 chr2:219372912 T/G cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs8056742 0.555 rs16975088 chr16:85017951 A/C cg00229868 chr16:85520891 NA -0.43 -5.19 -0.42 8.51e-7 Amyotrophic lateral sclerosis; TGCT cis rs367943 1.000 rs460079 chr5:112800525 G/A cg12552261 chr5:112820674 MCC -0.23 -4.78 -0.39 4.94e-6 Type 2 diabetes; TGCT cis rs4919694 1.000 rs7100592 chr10:104769098 T/G cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs1048238 0.818 rs2017577 chr1:16350123 C/G cg22431228 chr1:16359049 CLCNKA -0.3 -6.35 -0.5 3.64e-9 Systolic blood pressure; TGCT cis rs908922 0.676 rs6587686 chr1:152528948 C/T cg20991723 chr1:152506922 NA 0.45 6.06 0.48 1.55e-8 Hair morphology; TGCT cis rs2836950 0.501 rs2836983 chr21:40689336 G/A cg06238570 chr21:40685208 BRWD1 -0.63 -6.44 -0.5 2.42e-9 Menarche (age at onset); TGCT cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg24250549 chr1:154909240 PMVK 0.64 6.47 0.5 2.05e-9 Prostate cancer; TGCT cis rs72949976 0.934 rs10197392 chr2:214038178 G/A cg08319019 chr2:214017104 IKZF2 -0.81 -7.41 -0.55 1.74e-11 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg22535103 chr8:58192502 C8orf71 0.43 4.84 0.4 3.72e-6 Developmental language disorder (linguistic errors); TGCT cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg20637647 chr7:64974828 NA 0.9 5.29 0.43 5.42e-7 Diabetic kidney disease; TGCT cis rs68170813 0.559 rs9641378 chr7:106868003 T/C cg02696742 chr7:106810147 HBP1 -0.71 -5.76 -0.46 6.26e-8 Coronary artery disease; TGCT cis rs7647973 0.925 rs11130183 chr3:49228946 A/G cg07636037 chr3:49044803 WDR6 0.63 5.09 0.42 1.27e-6 Menarche (age at onset); TGCT cis rs4664308 1.000 rs10929966 chr2:160908341 C/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs2235642 0.821 rs2281234 chr16:1602938 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.64 -0.45 1.08e-7 Coronary artery disease; TGCT trans rs4650994 1.000 rs35810840 chr1:178522642 G/A cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.37e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7727544 0.816 rs274555 chr5:131722951 C/T cg24060327 chr5:131705240 SLC22A5 0.53 5.78 0.46 5.61e-8 Blood metabolite levels; TGCT cis rs6570726 0.791 rs9403734 chr6:145931459 C/G cg13319975 chr6:146136371 FBXO30 -0.53 -4.68 -0.39 7.51e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7258465 0.931 rs76195 chr19:18629830 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.89 0.4 3.03e-6 Breast cancer; TGCT cis rs7666738 0.753 rs28390295 chr4:99028497 C/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1468333 0.694 rs7719684 chr5:137614085 C/G cg27119451 chr5:137514611 BRD8;KIF20A 0.46 4.46 0.37 1.79e-5 Resting heart rate; TGCT cis rs9948 0.655 rs2314399 chr2:97442390 G/A cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT trans rs7613875 0.663 rs6762477 chr3:50093209 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.8 -8.32 -0.6 1.31e-13 Body mass index; TGCT cis rs2806561 0.734 rs2235548 chr1:23394062 G/A cg12483005 chr1:23474871 LUZP1 0.38 4.77 0.39 5e-6 Height; TGCT cis rs8072100 0.713 rs9899859 chr17:45513049 A/G cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs71636778 0.509 rs34667713 chr1:27292678 T/A cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs9549367 0.713 rs2476319 chr13:113836519 C/T cg09473364 chr13:112927190 NA 0.29 4.64 0.38 8.73e-6 Platelet distribution width; TGCT cis rs6964587 0.585 rs10266481 chr7:91554338 T/C cg17063962 chr7:91808500 NA -0.76 -7.25 -0.55 3.94e-11 Breast cancer; TGCT cis rs7659604 0.560 rs769238 chr4:122744942 G/A cg19748678 chr4:122722346 EXOSC9 0.9 9.35 0.64 4.81e-16 Type 2 diabetes; TGCT cis rs6582630 0.537 rs6582500 chr12:38534206 G/A cg26384229 chr12:38710491 ALG10B 0.89 8.13 0.59 3.76e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs10992471 0.580 rs7869521 chr9:95411059 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -4.57 -0.38 1.15e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3892630 0.588 rs7245709 chr19:33242755 C/T cg22980127 chr19:33182716 NUDT19 0.74 6.09 0.48 1.3e-8 Red blood cell traits; TGCT cis rs13382811 0.722 rs62169223 chr2:145251445 C/T cg21296320 chr2:145248607 ZEB2 0.36 4.55 0.38 1.27e-5 Myopia (severe); TGCT cis rs919433 0.653 rs700651 chr2:198631714 G/A cg00792783 chr2:198669748 PLCL1 0.55 4.92 0.4 2.66e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs10779751 0.770 rs1417131 chr1:11191922 T/C cg08854313 chr1:11322531 MTOR -0.84 -6.81 -0.52 3.82e-10 Body mass index; TGCT cis rs4788570 0.584 rs6499530 chr16:71723089 C/G cg06353428 chr16:71660113 MARVELD3 1.56 12.9 0.76 1.15e-24 Intelligence (multi-trait analysis); TGCT cis rs500492 0.542 rs400354 chr16:1074526 T/G cg01366354 chr16:1075121 NA 0.36 5.23 0.43 6.99e-7 Polycystic ovary syndrome; TGCT cis rs929596 0.793 rs13009407 chr2:234652347 C/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.34 -4.83 -0.4 3.95e-6 Total bilirubin levels in HIV-1 infection; TGCT cis rs6969780 0.915 rs4722659 chr7:27166750 C/T cg04317399 chr7:27170313 HOXA4 -0.44 -4.87 -0.4 3.3e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7582180 0.764 rs12615466 chr2:100924065 C/A cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs7953249 0.773 rs7979478 chr12:121420263 A/G cg02403541 chr12:121454288 C12orf43 -0.52 -4.48 -0.37 1.68e-5 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs2836950 0.520 rs8133928 chr21:40689963 G/A cg06238570 chr21:40685208 BRWD1 -0.63 -6.31 -0.49 4.41e-9 Menarche (age at onset); TGCT cis rs4845570 0.749 rs11576810 chr1:151712201 C/G cg07092448 chr1:151763213 TDRKH -1.03 -7.53 -0.56 8.99e-12 Coronary artery disease; TGCT cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg13012494 chr21:47604986 C21orf56 0.39 4.66 0.39 8.18e-6 Testicular germ cell tumor; TGCT cis rs17433780 0.504 rs4142706 chr1:89475230 A/C cg09516651 chr1:89888402 LOC400759 0.26 4.44 0.37 1.93e-5 Carotid intima media thickness; TGCT cis rs11577318 0.853 rs4471263 chr1:26622700 C/T cg12733254 chr1:26682999 NA -0.2 -4.59 -0.38 1.06e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs7727544 0.735 rs2569266 chr5:131706791 T/C cg24060327 chr5:131705240 SLC22A5 0.59 6.59 0.51 1.12e-9 Blood metabolite levels; TGCT cis rs9916302 0.904 rs8079560 chr17:37497661 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs6582630 0.555 rs10880611 chr12:38509316 C/G cg26384229 chr12:38710491 ALG10B 0.85 7.86 0.58 1.55e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs9467711 0.790 rs67777156 chr6:26633711 T/A cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs7809950 1.000 rs6976607 chr7:107223401 A/C cg23024343 chr7:107201750 COG5 0.33 5.13 0.42 1.09e-6 Coronary artery disease; TGCT cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs7208859 0.623 rs9890855 chr17:29111707 G/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs5750830 0.649 rs5750822 chr22:39826788 C/T cg01416388 chr22:39784598 NA -0.69 -7.12 -0.54 7.63e-11 Intelligence (multi-trait analysis); TGCT cis rs9309473 0.718 rs6546829 chr2:73613789 C/G cg20560298 chr2:73613845 ALMS1 -0.48 -5.39 -0.44 3.36e-7 Metabolite levels; TGCT cis rs1062177 1.000 rs12654573 chr5:151207473 T/G cg12924095 chr5:151150029 G3BP1 0.37 5.4 0.44 3.33e-7 Preschool internalizing problems; TGCT cis rs9814567 0.502 rs12634127 chr3:134256159 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.66 -6.84 -0.52 3.18e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10838634 1.000 rs7129622 chr11:46828895 A/G cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs9372498 0.505 rs9481789 chr6:118734320 A/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2404602 1.000 rs2120107 chr15:76869789 A/G cg22467129 chr15:76604101 ETFA -0.46 -5.33 -0.43 4.49e-7 Blood metabolite levels; TGCT cis rs6088580 0.634 rs2225837 chr20:33005634 C/T cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs56104184 0.775 rs55756106 chr19:49403055 A/G cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7267979 1.000 rs1046073 chr20:25281333 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs763014 0.932 rs2384974 chr16:651279 C/G cg09263875 chr16:632152 PIGQ 0.31 6.93 0.53 2.06e-10 Height; TGCT cis rs250677 0.687 rs40522 chr5:148442295 G/A cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs7523050 0.643 rs67567504 chr1:109402580 C/A cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT trans rs9393777 0.920 rs13212562 chr6:27300310 A/G cg00059246 chr12:54337929 HOXC13 0.62 7.5 0.56 1.06e-11 Intelligence (multi-trait analysis); TGCT cis rs931608 0.789 rs903937 chr19:22609988 G/C cg23859931 chr19:22123797 NA 0.6 4.51 0.38 1.45e-5 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs476633 0.708 rs8030657 chr15:41444979 T/C cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.77 -0.62 1.18e-14 Glomerular filtration rate (creatinine); TGCT cis rs4820539 0.966 rs5996470 chr22:23483255 G/A cg14186256 chr22:23484241 RTDR1 1.02 13.96 0.78 3.44e-27 Bone mineral density; TGCT cis rs7666738 0.716 rs11721453 chr4:99045485 G/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg11941060 chr3:133502564 NA -0.26 -5.24 -0.43 6.58e-7 Iron status biomarkers; TGCT cis rs1577917 0.958 rs12191340 chr6:86521400 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs7635838 0.819 rs2443709 chr3:11541814 C/T cg00170343 chr3:11313890 ATG7 0.67 6.26 0.49 5.88e-9 HDL cholesterol; TGCT cis rs3617 0.572 rs2245538 chr3:52852060 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.6 -0.38 1.02e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9394169 0.875 rs1547669 chr6:33775641 A/G cg00334056 chr6:33755658 LEMD2 -0.24 -4.55 -0.38 1.28e-5 Essential tremor; TGCT cis rs705471 0.762 rs555978 chr10:3662558 G/A cg14308648 chr10:3568949 NA 0.25 4.44 0.37 1.95e-5 Capecitabine sensitivity; TGCT trans rs7726839 0.540 rs72705030 chr5:645562 C/T cg11887960 chr12:57824829 NA 1.1 8.86 0.62 7.14e-15 Obesity-related traits; TGCT cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.52 -5.85 -0.47 4.02e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs200810 0.634 rs35172302 chr6:97991869 G/A cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.68 -4.62 -0.38 9.38e-6 Body mass index; TGCT cis rs2688608 0.901 rs2664282 chr10:75620757 T/C cg04320760 chr10:75533139 FUT11 -0.3 -4.66 -0.39 7.88e-6 Inflammatory bowel disease; TGCT cis rs6951245 1.000 rs78308415 chr7:1072634 G/A cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6121246 0.559 rs6058462 chr20:30367674 C/T cg10886678 chr20:30946050 ASXL1 -0.53 -4.5 -0.37 1.55e-5 Mean corpuscular hemoglobin; TGCT cis rs2075371 0.734 rs13225086 chr7:134011411 C/T cg11752832 chr7:134001865 SLC35B4 0.64 5.38 0.43 3.64e-7 Mean platelet volume; TGCT cis rs644799 0.735 rs10831432 chr11:95516040 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.8 9.01 0.63 3.14e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6964587 1.000 rs9690778 chr7:91735299 A/G cg17063962 chr7:91808500 NA 0.88 9.59 0.65 1.22e-16 Breast cancer; TGCT cis rs858239 0.600 rs10256524 chr7:23144947 T/C cg05602783 chr7:23145260 KLHL7 -0.67 -5.68 -0.45 9.25e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9916302 0.904 rs6503507 chr17:37525274 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs7973719 0.868 rs2053887 chr12:7346530 G/A cg07052231 chr12:7363540 PEX5 0.36 5.59 0.45 1.36e-7 IgG glycosylation; TGCT cis rs7819412 0.807 rs6991930 chr8:10963288 G/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.54 -0.38 1.29e-5 Triglycerides; TGCT cis rs713587 0.967 rs6749422 chr2:25150011 C/G cg01884057 chr2:25150051 NA 0.4 8.24 0.59 2.05e-13 Body mass index in non-asthmatics; TGCT cis rs6866344 0.570 rs4266420 chr5:178137161 C/G cg03877680 chr5:178157825 ZNF354A 0.74 6.56 0.51 1.28e-9 Neutrophil percentage of white cells; TGCT cis rs10782582 0.532 rs78106188 chr1:76137836 A/G cg03433033 chr1:76189801 ACADM -0.64 -7.35 -0.55 2.29e-11 Daytime sleep phenotypes; TGCT trans rs77457752 0.690 rs12349345 chr9:13912075 T/C cg12973904 chr7:149457885 NA 0.46 7.07 0.54 9.92e-11 Breast cancer; TGCT cis rs2050392 0.737 rs7898978 chr10:30699800 T/C cg18806716 chr10:30721971 MAP3K8 0.69 9.2 0.64 1.09e-15 Inflammatory bowel disease; TGCT cis rs4975709 0.569 rs4975742 chr5:1858612 T/C cg15595755 chr5:1867978 NA 0.46 5.11 0.42 1.18e-6 Cardiovascular disease risk factors; TGCT cis rs7772486 0.720 rs6931553 chr6:146112348 T/C cg05347473 chr6:146136440 FBXO30 -0.53 -4.99 -0.41 2.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7715806 0.500 rs2307112 chr5:75003413 A/C cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs2354432 0.556 rs11239964 chr1:146753902 G/C cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs6831352 0.918 rs17218073 chr4:100055739 G/A cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT trans rs2469997 0.623 rs2470023 chr8:120362995 T/A cg01792902 chr3:178864926 PIK3CA 0.83 6.66 0.51 7.86e-10 Hypertension (SNP x SNP interaction); TGCT cis rs12188164 1.000 rs56042615 chr5:437667 G/A cg26850624 chr5:429559 AHRR -0.2 -4.82 -0.4 4.05e-6 Cystic fibrosis severity; TGCT cis rs35883536 0.609 rs10783142 chr1:101043902 C/G cg14855972 chr1:101004472 GPR88 -0.23 -4.44 -0.37 1.97e-5 Monocyte count; TGCT cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs1801251 1.000 rs2674839 chr2:233669040 G/C cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs12477438 0.539 rs720228 chr2:99704547 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.53 0.84 2.35e-35 Chronic sinus infection; TGCT cis rs7769051 1.000 rs9493444 chr6:133125320 C/G cg07930552 chr6:133119739 C6orf192 0.94 5.04 0.41 1.6e-6 Type 2 diabetes nephropathy; TGCT trans rs17685 0.712 rs9800948 chr7:75810473 A/G cg19862616 chr7:65841803 NCRNA00174 0.47 8.5 0.61 4.97e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs3849570 1.000 rs11915016 chr3:81833966 G/A cg07356753 chr3:81810745 GBE1 -0.82 -7.62 -0.56 5.6e-12 Waist circumference;Body mass index; TGCT cis rs9527 0.568 rs1926036 chr10:104883812 C/T cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs6121246 0.529 rs73235789 chr20:30196148 T/C cg21427119 chr20:30132790 HM13 -0.39 -5.61 -0.45 1.25e-7 Mean corpuscular hemoglobin; TGCT cis rs7605378 0.528 rs1704191 chr2:200816393 C/A cg17644776 chr2:200775616 C2orf69 0.32 6.87 0.52 2.82e-10 Osteoporosis; TGCT cis rs2456568 0.867 rs7935801 chr11:93658000 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -5.96 -0.47 2.49e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs12762955 0.608 rs7922760 chr10:1156815 G/C cg20503657 chr10:835505 NA -0.42 -5.24 -0.43 6.69e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs7772486 0.727 rs10223508 chr6:146285205 C/T cg05347473 chr6:146136440 FBXO30 -0.52 -5.1 -0.42 1.25e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs78487399 0.808 rs10180005 chr2:43737465 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs13102973 0.965 rs11730310 chr4:135861925 A/G cg14419869 chr4:135874104 NA 0.24 4.46 0.37 1.83e-5 Subjective well-being; TGCT cis rs9921338 0.961 rs7206749 chr16:11376922 T/C cg00044050 chr16:11439710 C16orf75 -0.85 -6.04 -0.48 1.64e-8 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs617219 0.710 rs2591386 chr5:78561373 C/T cg05890484 chr5:78407552 BHMT 0.34 4.61 0.38 9.69e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs8028182 0.636 rs4322627 chr15:75810659 C/T cg20655648 chr15:75932815 IMP3 0.59 4.62 0.38 9.55e-6 Sudden cardiac arrest; TGCT cis rs7937682 0.855 rs527078 chr11:111479713 T/C cg09085632 chr11:111637200 PPP2R1B -0.97 -9.71 -0.66 6.56e-17 Primary sclerosing cholangitis; TGCT cis rs916888 0.821 rs199506 chr17:44859031 A/G cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg26354017 chr1:205819088 PM20D1 0.59 7.3 0.55 3.07e-11 Menarche (age at onset); TGCT cis rs7191439 0.522 rs8060640 chr16:88744430 G/C cg27087555 chr16:88793112 FAM38A -0.47 -4.74 -0.39 5.75e-6 Plateletcrit; TGCT cis rs7552404 0.960 rs4949877 chr1:76201668 C/G cg03433033 chr1:76189801 ACADM 0.82 9.74 0.66 5.46e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9303401 0.614 rs3803753 chr17:56540110 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.17 0.48 8.95e-9 Cognitive test performance; TGCT cis rs7914558 0.966 rs10748836 chr10:104693917 G/A cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs13082711 0.513 rs66472045 chr3:27242887 G/A cg02860705 chr3:27208620 NA 0.44 6.78 0.52 4.43e-10 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs17376456 0.825 rs10054790 chr5:93272520 A/G cg25358565 chr5:93447407 FAM172A 1.03 8.1 0.59 4.5e-13 Diabetic retinopathy; TGCT cis rs3796352 1.000 rs11718538 chr3:52975987 C/G cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6840360 0.806 rs13149588 chr4:152717757 C/T cg22705602 chr4:152727874 NA 0.25 4.61 0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT cis rs12615966 0.651 rs72830472 chr2:105407426 C/T cg16465502 chr2:105461796 NA 0.85 5.6 0.45 1.34e-7 Pancreatic cancer; TGCT cis rs67460515 0.892 rs73026976 chr3:160964271 G/A cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT cis rs8014204 0.566 rs7145575 chr14:75145528 T/A cg06637938 chr14:75390232 RPS6KL1 0.61 5.51 0.44 1.97e-7 Caffeine consumption; TGCT cis rs6586111 1.000 rs7086576 chr10:82372145 C/G cg03086067 chr10:82368399 SH2D4B -0.24 -4.7 -0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg12386194 chr3:101231763 SENP7 0.59 5.39 0.44 3.43e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11105298 0.891 rs11105299 chr12:89877943 A/G cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs931127 0.617 rs10896027 chr11:65420760 C/G cg27068330 chr11:65405492 SIPA1 0.56 4.94 0.41 2.47e-6 Systemic lupus erythematosus; TGCT cis rs921968 0.643 rs645796 chr2:219389236 A/G cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs9913156 0.789 rs56003988 chr17:4600764 G/A cg23387401 chr17:4582204 PELP1 0.31 4.68 0.39 7.44e-6 Lymphocyte counts; TGCT cis rs72627509 0.680 rs79641006 chr4:57847443 T/G cg26694713 chr4:57773883 REST 0.64 4.83 0.4 3.94e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6964587 0.967 rs2282969 chr7:91583772 T/C cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs950169 0.595 rs11631921 chr15:85143277 G/A cg17173187 chr15:85201210 NMB 0.51 5.43 0.44 2.9e-7 Schizophrenia; TGCT cis rs6840360 0.593 rs1877185 chr4:152690348 C/T cg17479576 chr4:152424074 FAM160A1 -0.57 -5.47 -0.44 2.35e-7 Intelligence (multi-trait analysis); TGCT cis rs10501293 0.703 rs7937104 chr11:43008528 A/G cg03447554 chr11:43094025 NA 0.5 5.81 0.46 5.06e-8 Cognitive performance; TGCT cis rs2839186 0.872 rs2250213 chr21:47674275 G/A cg13732083 chr21:47605072 C21orf56 0.37 4.85 0.4 3.62e-6 Testicular germ cell tumor; TGCT cis rs2456568 0.900 rs877340 chr11:93689292 A/T cg16099599 chr11:93583650 C11orf90 -0.39 -4.71 -0.39 6.41e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6089829 0.925 rs3746748 chr20:61667526 C/T cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs11626933 0.959 rs2149649 chr14:90774974 A/G cg14092571 chr14:90743983 NA 0.31 6.27 0.49 5.59e-9 Gut microbiota (bacterial taxa); TGCT cis rs4851251 1.000 rs4851251 chr2:100753490 C/T cg07810366 chr2:100720526 AFF3 0.41 5.27 0.43 5.8e-7 Educational attainment (years of education); TGCT cis rs4478037 0.732 rs12490111 chr3:33103007 G/A cg19404215 chr3:33155277 CRTAP 1.24 5.97 0.47 2.36e-8 Major depressive disorder; TGCT cis rs7091068 0.616 rs10748611 chr10:95482761 A/C cg20715218 chr10:95462985 C10orf4 0.56 5.29 0.43 5.36e-7 Urinary tract infection frequency; TGCT cis rs4148883 0.545 rs17595102 chr4:99986316 C/G cg12011299 chr4:100065546 ADH4 0.39 5.67 0.45 9.5e-8 Alcohol dependence; TGCT cis rs2115630 0.805 rs8042926 chr15:85205454 T/A cg17173187 chr15:85201210 NMB -0.36 -4.46 -0.37 1.84e-5 P wave terminal force; TGCT cis rs7666738 0.830 rs1869082 chr4:98841254 T/A cg05340658 chr4:99064831 C4orf37 0.53 6.17 0.48 8.71e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs6656435 chr1:154876869 G/A cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs6921919 0.583 rs9468368 chr6:28364949 G/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.790 rs2265474 chr6:146182092 G/A cg05347473 chr6:146136440 FBXO30 0.53 4.99 0.41 2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs617219 0.671 rs12189188 chr5:78552312 C/T cg05890484 chr5:78407552 BHMT 0.38 5.17 0.42 9.01e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs597539 0.652 rs488363 chr11:68658298 C/G cg06028808 chr11:68637592 NA 0.51 6.54 0.51 1.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg22618164 chr12:122356400 WDR66 0.62 6.43 0.5 2.53e-9 Mean corpuscular volume; TGCT cis rs12497850 0.931 rs7623023 chr3:48914238 G/A cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs11098499 0.909 rs17046118 chr4:120387496 T/G cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs9527 0.571 rs4917985 chr10:104624072 C/T cg15744005 chr10:104629667 AS3MT -0.49 -6.13 -0.48 1.07e-8 Arsenic metabolism; TGCT cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg19635926 chr16:89946313 TCF25 0.27 4.58 0.38 1.11e-5 Skin colour saturation; TGCT cis rs7107356 1 rs7107356 chr11:47676170 A/G cg20307385 chr11:47447363 PSMC3 0.51 4.65 0.39 8.33e-6 Neuroticism;Neuroticism (multi-trait analysis); TGCT cis rs2777491 1.000 rs66538814 chr15:41685917 G/T cg18705301 chr15:41695430 NDUFAF1 -0.73 -10.41 -0.68 1.24e-18 Ulcerative colitis; TGCT cis rs473651 0.967 rs483042 chr2:239335320 A/G cg18131467 chr2:239335373 ASB1 0.99 14.15 0.79 1.2100000000000001e-27 Multiple system atrophy; TGCT cis rs6867032 1.000 rs7729761 chr5:2015783 G/T cg26168224 chr5:2018326 NA 0.43 7.96 0.58 9.31e-13 Gut microbiome composition (winter); TGCT cis rs7552404 0.824 rs1251077 chr1:76189745 C/G cg22875332 chr1:76189707 ACADM -0.82 -12.71 -0.75 3.22e-24 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12643440 0.538 rs16894418 chr4:17141112 T/C cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs28493229 0.881 rs59459325 chr19:41175390 C/T cg11601297 chr19:41224147 ITPKC;ADCK4 0.59 5.69 0.46 8.61e-8 Kawasaki disease; TGCT cis rs2688608 0.967 rs2633299 chr10:75656754 T/G cg02947784 chr10:75434997 AGAP5 0.16 4.56 0.38 1.21e-5 Inflammatory bowel disease; TGCT cis rs61897795 0.657 rs174589 chr11:61615803 C/G cg19610905 chr11:61596333 FADS2 0.76 5.97 0.47 2.37e-8 Neutrophil count;Sum basophil neutrophil counts; TGCT cis rs6088580 0.634 rs1890000 chr20:32968312 G/T cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs3858526 0.959 rs61876224 chr11:5952859 G/A cg13902645 chr11:5959945 NA -0.44 -4.78 -0.39 4.77e-6 DNA methylation (variation); TGCT cis rs9467711 0.606 rs1978 chr6:26377573 A/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs80282103 0.618 rs74117831 chr10:1145707 A/C cg08668510 chr10:1095578 IDI1 1.05 5.31 0.43 4.8e-7 Glomerular filtration rate (creatinine); TGCT trans rs62103177 0.564 rs7228971 chr18:77738025 C/T cg05926928 chr17:57297772 GDPD1 -0.79 -6.84 -0.52 3.26e-10 Opioid sensitivity; TGCT cis rs9894429 0.624 rs9910935 chr17:79613949 T/C cg18240062 chr17:79603768 NPLOC4 0.84 9.37 0.64 4.28e-16 Eye color traits; TGCT trans rs877282 0.898 rs11253344 chr10:765162 C/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg10883421 chr6:151773342 RMND1;C6orf211 0.81 9.15 0.63 1.44e-15 Menarche (age at onset); TGCT cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.84 0.46 4.3e-8 Bipolar disorder; TGCT cis rs7208859 0.673 rs9914271 chr17:29232625 G/A cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2204008 0.774 rs4534658 chr12:38246783 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.43 0.55 1.57e-11 Bladder cancer; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg25767906 chr1:53392781 SCP2 -0.53 -6.21 -0.49 7.34e-9 Monocyte count; TGCT cis rs910316 1.000 rs10136948 chr14:75511075 C/T cg08847533 chr14:75593920 NEK9 0.96 10.89 0.7 8.43e-20 Height; TGCT cis rs4975709 0.569 rs931509 chr5:1858821 A/T cg07747251 chr5:1868357 NA 0.38 5.31 0.43 4.95e-7 Cardiovascular disease risk factors; TGCT cis rs73001065 0.901 rs8107974 chr19:19388500 A/T cg03709012 chr19:19516395 GATAD2A 1.02 4.87 0.4 3.32e-6 LDL cholesterol; TGCT cis rs79387448 0.745 rs7583683 chr2:103113763 C/T cg09003973 chr2:102972529 NA -0.84 -5.66 -0.45 9.87e-8 Gut microbiota (bacterial taxa); TGCT cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg08048268 chr3:133502702 NA -0.54 -7.03 -0.53 1.21e-10 Iron status biomarkers; TGCT cis rs9942416 0.660 rs60423072 chr5:75006113 T/A cg02573091 chr5:74908125 NA 0.43 4.88 0.4 3.24e-6 Age-related disease endophenotypes; TGCT cis rs9394169 0.514 rs1886355 chr6:33776877 C/T cg13859433 chr6:33739653 LEMD2 -0.33 -5.85 -0.47 4.02e-8 Essential tremor; TGCT cis rs9911578 0.935 rs302873 chr17:56769481 C/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs2239547 0.522 rs2564947 chr3:53046216 C/T cg10802521 chr3:52805072 NEK4 0.6 5.58 0.45 1.43e-7 Schizophrenia; TGCT cis rs11191270 0.554 rs11191253 chr10:104066507 A/T cg15320455 chr10:103880129 LDB1 0.82 5.13 0.42 1.11e-6 Intelligence (multi-trait analysis); TGCT cis rs3125734 0.633 rs1873685 chr10:64032126 C/T cg09941381 chr10:64027924 RTKN2 -0.37 -5.63 -0.45 1.14e-7 Rheumatoid arthritis; TGCT cis rs910316 0.737 rs2098251 chr14:75492696 G/A cg08847533 chr14:75593920 NEK9 0.84 8.77 0.62 1.16e-14 Height; TGCT cis rs7909074 0.966 rs4268464 chr10:45401081 T/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.35 -0.43 4.05e-7 Mean corpuscular volume; TGCT cis rs7412746 0.611 rs7556661 chr1:150892009 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs4699052 0.625 rs4481237 chr4:104254009 G/A cg16532752 chr4:104119610 CENPE -0.5 -4.92 -0.4 2.71e-6 Testicular germ cell tumor; TGCT cis rs6570726 1.000 rs455109 chr6:145872665 C/T cg05347473 chr6:146136440 FBXO30 0.5 4.46 0.37 1.82e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9560113 1.000 rs2104790 chr13:112177412 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs11098499 0.954 rs10008392 chr4:120318839 G/A cg09307838 chr4:120376055 NA 0.65 6.18 0.49 8.36e-9 Corneal astigmatism; TGCT cis rs4689388 0.926 rs4416547 chr4:6293967 G/A cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2239547 0.603 rs6789219 chr3:53098938 C/G cg11645453 chr3:52864694 ITIH4 0.31 4.93 0.4 2.61e-6 Schizophrenia; TGCT cis rs478607 0.831 rs61884374 chr11:64388929 A/G cg19395706 chr11:64412079 NRXN2 0.48 4.84 0.4 3.8e-6 Urate levels; TGCT cis rs11785400 0.793 rs9297970 chr8:143723386 C/T cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs9581857 0.547 rs9581870 chr13:28083957 T/G cg22138327 chr13:27999177 GTF3A 0.72 4.51 0.38 1.46e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs1008375 0.932 rs6835077 chr4:17653285 A/T cg18681998 chr4:17616180 MED28 0.98 10.79 0.7 1.49e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs904251 0.504 rs9380677 chr6:37480366 A/G cg25019722 chr6:37503610 NA -0.54 -8.18 -0.59 2.84e-13 Cognitive performance; TGCT cis rs11190604 1.000 rs4244338 chr10:102272802 A/G cg16342193 chr10:102329863 NA -0.41 -5.2 -0.42 7.99e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7772486 0.714 rs1883365 chr6:146076749 C/T cg05347473 chr6:146136440 FBXO30 -0.49 -4.52 -0.38 1.42e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs868036 0.681 rs2241423 chr15:68086838 G/A cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs1371867 0.875 rs962451 chr8:101331010 C/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs6952808 0.609 rs34967784 chr7:1949507 T/G cg04267008 chr7:1944627 MAD1L1 -0.37 -4.81 -0.4 4.23e-6 Bipolar disorder and schizophrenia; TGCT cis rs9399135 0.967 rs10872427 chr6:135353452 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.77 0.39 5.14e-6 Red blood cell count; TGCT cis rs6089584 0.819 rs1467593 chr20:60601432 T/G cg06108461 chr20:60628389 TAF4 0.64 9.5 0.65 2.08e-16 Body mass index; TGCT cis rs1862618 0.715 rs6866779 chr5:56090000 G/A cg20203395 chr5:56204925 C5orf35 -0.57 -4.82 -0.4 4.15e-6 Initial pursuit acceleration; TGCT cis rs7159131 0.711 rs10141466 chr14:36995776 T/G cg07345734 chr14:36986363 NKX2-1 -0.49 -4.61 -0.38 1e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.562 rs12497998 chr3:52793602 C/T cg10802521 chr3:52805072 NEK4 -0.81 -10.05 -0.67 9.7e-18 Bipolar disorder; TGCT cis rs7914558 0.966 rs3977751 chr10:104920232 A/G cg05855489 chr10:104503620 C10orf26 0.52 4.53 0.38 1.35e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3820068 0.608 rs12092485 chr1:16048038 A/G cg05660106 chr1:15850417 CASP9 0.75 6.85 0.52 3.06e-10 Systolic blood pressure; TGCT cis rs8177253 0.965 rs3811658 chr3:133476852 C/T cg16414030 chr3:133502952 NA -0.6 -9.07 -0.63 2.25e-15 Iron status biomarkers; TGCT cis rs56399783 0.901 rs7803944 chr7:2809087 G/A cg19731401 chr7:2775893 GNA12 0.35 5.09 0.42 1.28e-6 Childhood ear infection; TGCT cis rs10791323 0.569 rs11223609 chr11:133741766 C/T cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs7572733 0.534 rs6434943 chr2:198762192 T/G cg00792783 chr2:198669748 PLCL1 0.56 5.11 0.42 1.21e-6 Dermatomyositis; TGCT cis rs7267979 0.932 rs6138588 chr20:25487523 C/T cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.754 rs2064185 chr6:146066814 G/A cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs6952808 0.531 rs3779002 chr7:2183219 C/T cg22963979 chr7:1858916 MAD1L1 -0.41 -6.48 -0.5 1.98e-9 Bipolar disorder and schizophrenia; TGCT cis rs6684514 1.000 rs12132794 chr1:156281020 C/G cg16558208 chr1:156270281 VHLL -0.48 -9.6 -0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6674176 0.593 rs3791120 chr1:44431715 T/C cg13606994 chr1:44402422 ARTN -0.46 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9325144 0.671 rs12818797 chr12:39019409 A/G cg13010199 chr12:38710504 ALG10B -0.51 -4.58 -0.38 1.13e-5 Morning vs. evening chronotype; TGCT cis rs4700695 0.764 rs251593 chr5:65313889 G/A cg21114390 chr5:65439923 SFRS12 0.61 4.56 0.38 1.19e-5 Facial morphology (factor 19); TGCT cis rs7659604 0.676 rs4077102 chr4:122699830 A/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.71 -0.46 7.8e-8 Type 2 diabetes; TGCT cis rs826838 0.967 rs826879 chr12:39088999 A/C cg26384229 chr12:38710491 ALG10B -0.88 -8.19 -0.59 2.72e-13 Heart rate; TGCT cis rs6998277 0.830 rs12543008 chr8:103603747 C/T cg10187029 chr8:103597600 NA 0.56 8.83 0.62 8.12e-15 Migraine; TGCT cis rs2072499 0.838 rs2758619 chr1:156162559 A/G cg06970220 chr1:156163860 SLC25A44 0.72 6.3 0.49 4.62e-9 Testicular germ cell tumor; TGCT cis rs7772486 0.875 rs9373483 chr6:146364194 A/G cg05347473 chr6:146136440 FBXO30 0.56 5.42 0.44 2.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6088580 0.634 rs6579165 chr20:32994715 A/G cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs17387100 1.000 rs73230286 chr4:15993149 A/C cg14577840 chr4:16257979 FLJ39653 0.47 4.51 0.38 1.5e-5 Suicide attempts in depression or bipolar disorder; TGCT cis rs1568889 0.887 rs7102237 chr11:28344296 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 10.99 0.7 4.8e-20 Bipolar disorder; TGCT cis rs11648796 0.757 rs66649828 chr16:766078 A/G cg07343612 chr16:622815 PIGQ -0.34 -5.01 -0.41 1.85e-6 Height; TGCT cis rs2862064 0.932 rs1553317 chr5:156479424 A/C cg12943317 chr5:156479607 HAVCR1 -0.45 -5.83 -0.46 4.42e-8 Platelet count; TGCT cis rs4499344 0.657 rs402862 chr19:33111102 C/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.72 7.38 0.55 1.99e-11 Mean platelet volume; TGCT cis rs2688608 0.592 rs7923045 chr10:75487498 A/T cg04320760 chr10:75533139 FUT11 -0.41 -6.53 -0.51 1.49e-9 Inflammatory bowel disease; TGCT cis rs12464483 0.591 rs72800120 chr2:30897122 G/A cg17749961 chr2:30669863 LCLAT1 0.7 5.27 0.43 5.97e-7 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs1018836 0.923 rs6999898 chr8:91650549 G/A cg16814680 chr8:91681699 NA -0.85 -8.84 -0.62 7.95e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs12220238 1.000 rs7897778 chr10:75916105 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.88 7.24 0.55 4.04e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs10114408 0.959 rs7847426 chr9:96642908 A/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT trans rs2727020 0.731 rs10450572 chr11:49281073 T/C cg15704280 chr7:45808275 SEPT13 0.73 8.33 0.6 1.27e-13 Coronary artery disease; TGCT cis rs2486288 0.656 rs8037583 chr15:45546378 A/G cg14582100 chr15:45693742 SPATA5L1 -0.44 -5.39 -0.44 3.35e-7 Glomerular filtration rate; TGCT cis rs3858526 0.959 rs10838795 chr11:5920721 A/G cg05234568 chr11:5960015 NA 0.43 4.52 0.38 1.4e-5 DNA methylation (variation); TGCT cis rs8031584 0.752 rs1852035 chr15:31184803 C/G cg14829155 chr15:31115871 NA -0.34 -4.57 -0.38 1.17e-5 Huntington's disease progression; TGCT cis rs12711979 1.000 rs12711979 chr2:3869559 A/G cg17052675 chr2:3827356 NA -0.32 -5.85 -0.46 4.12e-8 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7914558 0.752 rs7896519 chr10:104866863 C/T cg15744005 chr10:104629667 AS3MT -0.45 -5.55 -0.45 1.65e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1113500 0.787 rs10881501 chr1:108641745 C/T cg22161131 chr1:109420278 GPSM2 0.5 4.6 0.38 1.02e-5 Growth-regulated protein alpha levels; TGCT cis rs734999 0.550 rs2985855 chr1:2531372 A/C cg18854424 chr1:2615690 NA -0.46 -5.36 -0.43 3.84e-7 Ulcerative colitis; TGCT cis rs2046867 0.818 rs62249861 chr3:72867779 A/G cg25664220 chr3:72788482 NA -0.56 -7.04 -0.53 1.16e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2243480 1.000 rs316332 chr7:65604299 A/G cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs3845702 0.736 rs72958863 chr2:180808144 C/T cg01881094 chr2:180872142 CWC22 1.04 6.58 0.51 1.16e-9 Schizophrenia; TGCT cis rs4757319 0.656 rs4334003 chr11:15345573 G/T cg26427818 chr11:15093613 NA -0.39 -4.76 -0.39 5.38e-6 Breast cancer; TGCT cis rs28735056 0.967 rs623546 chr18:77595228 C/T cg20368463 chr18:77673604 PQLC1 -0.45 -5.53 -0.44 1.84e-7 Schizophrenia; TGCT cis rs6582630 0.519 rs8186881 chr12:38310285 A/G cg13010199 chr12:38710504 ALG10B 0.57 4.49 0.37 1.62e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs17376456 0.569 rs7721668 chr5:93290995 G/A cg25358565 chr5:93447407 FAM172A -0.62 -5.97 -0.47 2.33e-8 Diabetic retinopathy; TGCT cis rs9467711 0.651 rs71557316 chr6:26072981 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.6 -4.67 -0.39 7.83e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2013441 1.000 rs1373147 chr17:20206645 T/A cg18979559 chr17:20280153 CCDC144C -0.49 -4.99 -0.41 1.97e-6 Obesity-related traits; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg02953382 chr22:24373134 LOC391322 -0.81 -7.23 -0.54 4.31e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg27211696 chr2:191398769 TMEM194B 0.29 5.3 0.43 5.19e-7 Pulse pressure; TGCT cis rs8031584 0.678 rs8035703 chr15:31168472 T/C cg08109568 chr15:31115862 NA -0.38 -5.03 -0.41 1.67e-6 Huntington's disease progression; TGCT cis rs11190604 0.943 rs7900678 chr10:102229016 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12681287 0.604 rs7017716 chr8:87429001 A/C cg27223183 chr8:87520930 FAM82B -0.81 -6.15 -0.48 9.62e-9 Caudate activity during reward; TGCT cis rs950169 0.881 rs150965 chr15:85080527 T/G cg17173187 chr15:85201210 NMB 0.54 5.51 0.44 2.01e-7 Schizophrenia; TGCT cis rs11190604 1.000 rs7088512 chr10:102303498 G/T cg16342193 chr10:102329863 NA -0.4 -4.89 -0.4 3e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2862064 1.000 rs1501910 chr5:156418790 A/G cg12943317 chr5:156479607 HAVCR1 -0.41 -5.41 -0.44 3.17e-7 Platelet count; TGCT cis rs4654899 0.627 rs637990 chr1:21047616 A/G cg01072550 chr1:21505969 NA 0.39 5.91 0.47 3.05e-8 Superior frontal gyrus grey matter volume; TGCT trans rs11722228 0.522 rs73212808 chr4:10055439 G/C cg26043149 chr18:55253948 FECH 1.15 11.94 0.73 2.46e-22 Gout;Urate levels;Serum uric acid levels; TGCT cis rs7975161 0.640 rs10735394 chr12:104687142 C/A cg25273343 chr12:104657179 TXNRD1 -0.32 -4.52 -0.38 1.42e-5 Toenail selenium levels; TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs1862618 0.671 rs2591957 chr5:56243146 A/T cg12311346 chr5:56204834 C5orf35 0.55 5.89 0.47 3.44e-8 Initial pursuit acceleration; TGCT cis rs11673344 0.504 rs8110796 chr19:37623584 C/T cg08039142 chr19:36980659 ZNF566 0.51 4.68 0.39 7.31e-6 Obesity-related traits; TGCT cis rs4975709 0.589 rs4975707 chr5:1864028 C/T cg12288994 chr5:1860383 NA 0.25 4.81 0.4 4.25e-6 Cardiovascular disease risk factors; TGCT cis rs4819052 0.808 rs2838825 chr21:46655651 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.68 6.05 0.48 1.58e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2730245 0.510 rs2788471 chr7:158649786 G/T cg11984989 chr7:158649758 WDR60 1.05 9.85 0.66 2.94e-17 Height; TGCT cis rs7249142 0.549 rs62135499 chr19:19294237 T/C cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.54 5.36 0.43 3.9e-7 IgG glycosylation; TGCT cis rs9291683 0.588 rs3796829 chr4:10019138 C/G cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Bone mineral density; TGCT cis rs9611565 0.649 rs6002480 chr22:42176917 A/T cg17554472 chr22:41940697 POLR3H -0.43 -4.58 -0.38 1.13e-5 Vitiligo; TGCT cis rs4906332 1.000 rs13987 chr14:103969909 A/G cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs3733631 1.000 rs1905172 chr4:104636034 C/T cg24090629 chr4:104641072 TACR3 -0.74 -5.81 -0.46 5.02e-8 Menarche (age at onset); TGCT cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg10802521 chr3:52805072 NEK4 0.74 9.07 0.63 2.26e-15 Bipolar disorder; TGCT cis rs6922617 1.000 rs6922617 chr6:41336101 C/T cg07798131 chr6:41471673 NA 0.81 4.46 0.37 1.8e-5 Alzheimer's disease biomarkers; TGCT cis rs6076065 0.548 rs1112818 chr20:23323936 G/A cg11657817 chr20:23433608 CST11 0.28 5.0 0.41 1.95e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs7666738 0.753 rs2903143 chr4:99040480 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10206020 0.921 rs9678719 chr2:1549628 A/G cg01028140 chr2:1542097 TPO -0.32 -4.65 -0.39 8.2e-6 IgG glycosylation; TGCT cis rs769267 0.965 rs2017964 chr19:19387149 T/C cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs826838 0.935 rs4583043 chr12:38645147 T/G cg13010199 chr12:38710504 ALG10B 0.74 5.94 0.47 2.67e-8 Heart rate; TGCT cis rs2692947 0.673 rs4907279 chr2:96399968 G/C cg23100626 chr2:96804247 ASTL 0.38 4.5 0.37 1.55e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs11096990 0.613 rs12505690 chr4:39169045 G/A cg24403649 chr4:39172243 NA 0.2 4.48 0.37 1.7e-5 Cognitive function; TGCT cis rs4820792 0.725 rs1884817 chr22:29106945 G/C cg03733026 chr22:29445468 ZNRF3 0.25 4.85 0.4 3.67e-6 Breast size; TGCT cis rs2153535 0.580 rs7742794 chr6:8459723 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2354432 1.000 rs7514864 chr1:146690102 T/C cg25205988 chr1:146714368 CHD1L 1.24 7.08 0.54 9.53e-11 Mitochondrial DNA levels; TGCT cis rs7772486 0.686 rs9390347 chr6:146044747 G/T cg23711669 chr6:146136114 FBXO30 -0.88 -9.77 -0.66 4.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg21433313 chr16:3507492 NAT15 -0.37 -4.71 -0.39 6.45e-6 Tuberculosis; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg01802117 chr1:53393560 SCP2 -0.46 -5.94 -0.47 2.74e-8 Monocyte count; TGCT cis rs17376456 0.877 rs13165147 chr5:93422214 G/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs6570726 0.577 rs403345 chr6:145845171 T/C cg13319975 chr6:146136371 FBXO30 -0.7 -6.36 -0.5 3.5e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs6050566 chr20:25351071 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.55 0.69 5.84e-19 Colorectal cancer; TGCT cis rs849210 0.580 rs4675513 chr2:206179222 A/T cg11793701 chr2:206547163 NRP2 -0.54 -4.49 -0.37 1.62e-5 Tonsillectomy; TGCT cis rs7172809 0.599 rs3784788 chr15:77759896 C/T cg22256960 chr15:77711686 NA -0.5 -4.69 -0.39 7.07e-6 Glucose homeostasis traits; TGCT cis rs12497850 0.966 rs6792510 chr3:48723302 G/C cg07636037 chr3:49044803 WDR6 0.9 9.43 0.65 2.99e-16 Parkinson's disease; TGCT cis rs12477438 0.520 rs4851188 chr2:99745898 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs3008870 0.959 rs2985808 chr1:67367741 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.84 0.73 4.25e-22 Lymphocyte percentage of white cells; TGCT cis rs2153535 0.580 rs7743686 chr6:8526111 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs6964587 0.967 rs34574955 chr7:91847550 A/C cg22709100 chr7:91322751 NA 0.28 4.51 0.38 1.49e-5 Breast cancer; TGCT cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg10411590 chr13:21900810 NA 0.38 5.06 0.41 1.48e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs12210905 0.688 rs60888769 chr6:27490922 A/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs6988636 1.000 rs7002332 chr8:124185442 G/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs782590 0.935 rs10460508 chr2:55882565 A/C cg03859395 chr2:55845619 SMEK2 0.89 10.46 0.68 9.87e-19 Metabolic syndrome; TGCT cis rs35883536 0.626 rs10783140 chr1:101042083 A/G cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.1e-12 Monocyte count; TGCT cis rs7178424 0.516 rs7163326 chr15:62338559 A/G cg00456672 chr15:62358751 C2CD4A -0.29 -4.45 -0.37 1.88e-5 Height; TGCT cis rs2066819 1.000 rs41423244 chr12:56693520 A/C cg26714650 chr12:56694279 CS 1.36 6.06 0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs2235642 0.787 rs2235646 chr16:1601287 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.33 -5.58 -0.45 1.43e-7 Coronary artery disease; TGCT cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.1 14.88 0.8 2.36e-29 Height; TGCT cis rs12216125 0.537 rs12207059 chr6:25922385 C/T cg17042849 chr6:26104293 HIST1H4C -0.78 -5.66 -0.45 9.93e-8 Iron status biomarkers; TGCT cis rs4919694 1.000 rs79254677 chr10:104691567 A/G cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.92e-11 Arsenic metabolism; TGCT cis rs2115630 0.818 rs7176522 chr15:85215383 C/G cg11189052 chr15:85197271 WDR73 -0.7 -7.04 -0.53 1.18e-10 P wave terminal force; TGCT cis rs950169 0.512 rs4374136 chr15:84645007 C/G cg11189052 chr15:85197271 WDR73 0.67 4.79 0.4 4.68e-6 Schizophrenia; TGCT cis rs77633900 0.614 rs113557153 chr15:76994445 A/G cg21673338 chr15:77095150 SCAPER -0.49 -4.7 -0.39 6.76e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs17376456 0.778 rs72786662 chr5:93137630 C/T cg21475434 chr5:93447410 FAM172A 0.62 4.67 0.39 7.58e-6 Diabetic retinopathy; TGCT cis rs9325144 0.560 rs1825802 chr12:38650341 C/T cg26384229 chr12:38710491 ALG10B -0.63 -5.92 -0.47 2.9e-8 Morning vs. evening chronotype; TGCT cis rs9303401 0.538 rs10515155 chr17:56481944 A/G cg25039879 chr17:56429692 SUPT4H1 0.58 5.04 0.41 1.63e-6 Cognitive test performance; TGCT cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg04608855 chr19:58913158 NA 0.53 5.09 0.42 1.31e-6 Uric acid clearance; TGCT cis rs6089829 0.925 rs6122086 chr20:61664528 T/C cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs6688613 0.685 rs2235184 chr1:166870528 A/G cg07049167 chr1:166818506 POGK -0.27 -5.64 -0.45 1.07e-7 Refractive astigmatism; TGCT cis rs7833790 0.700 rs28390260 chr8:82769175 A/T cg17211192 chr8:82754475 SNX16 0.97 9.09 0.63 2.04e-15 Diastolic blood pressure; TGCT cis rs597539 0.652 rs514296 chr11:68654182 G/T cg06028808 chr11:68637592 NA 0.51 6.55 0.51 1.38e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg05025164 chr4:1340916 KIAA1530 0.68 5.65 0.45 1.07e-7 Longevity; TGCT cis rs7635838 0.826 rs9867963 chr3:11469126 C/T cg00170343 chr3:11313890 ATG7 0.68 6.55 0.51 1.41e-9 HDL cholesterol; TGCT cis rs2073300 1.000 rs6114135 chr20:23456746 C/A cg09953122 chr20:23471693 CST8 -0.59 -4.7 -0.39 6.74e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs12477438 0.520 rs6717723 chr2:99756930 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.05 0.63 2.42e-15 Chronic sinus infection; TGCT cis rs1997103 1.000 rs6977292 chr7:55396335 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs12477438 0.784 rs13407840 chr2:99569928 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7666738 0.512 rs1648536 chr4:99019881 G/T cg17366294 chr4:99064904 C4orf37 -0.54 -5.86 -0.47 3.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.654 rs1011597 chr6:146075672 A/C cg23711669 chr6:146136114 FBXO30 -0.9 -10.02 -0.67 1.11e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7615952 0.611 rs7632305 chr3:125634767 C/T cg05084668 chr3:125655381 ALG1L -0.69 -4.49 -0.37 1.62e-5 Blood pressure (smoking interaction); TGCT cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7659604 0.521 rs4240263 chr4:122683623 C/T cg19748678 chr4:122722346 EXOSC9 -0.51 -5.17 -0.42 8.96e-7 Type 2 diabetes; TGCT cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg03264133 chr6:25882463 NA -0.58 -5.89 -0.47 3.44e-8 Blood metabolite levels; TGCT cis rs1570884 0.516 rs2146144 chr13:50170245 C/T cg08779649 chr13:50194554 NA 0.37 5.82 0.46 4.74e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg07157834 chr1:205819609 PM20D1 -0.36 -5.62 -0.45 1.19e-7 Monocyte percentage of white cells; TGCT cis rs2153535 0.580 rs1577471 chr6:8485905 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT trans rs916888 0.697 rs199516 chr17:44856485 C/T cg01341218 chr17:43662625 NA -1.12 -9.65 -0.65 8.83e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs13242816 1.000 rs13233553 chr7:116182232 C/G cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs797680 0.856 rs627779 chr1:93684089 T/C cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11031096 0.727 rs7940013 chr11:4138304 C/T cg18678763 chr11:4115507 RRM1 -0.47 -5.86 -0.47 4e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9611565 0.559 rs7290990 chr22:41964357 C/A cg03806693 chr22:41940476 POLR3H -1.08 -11.36 -0.71 6.34e-21 Vitiligo; TGCT cis rs4727027 0.651 rs12704068 chr7:148856153 T/C cg15662616 chr7:148823355 ZNF425;ZNF398 0.55 4.52 0.38 1.42e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg06600287 chr1:53387719 ECHDC2 -0.21 -4.57 -0.38 1.17e-5 Monocyte count; TGCT cis rs2797160 0.967 rs1739368 chr6:126011079 C/T cg05901451 chr6:126070800 HEY2 0.75 6.33 0.49 4.14e-9 Endometrial cancer; TGCT cis rs9549367 0.713 rs2476319 chr13:113836519 C/T cg18105134 chr13:113819100 PROZ 0.46 8.58 0.61 3.25e-14 Platelet distribution width; TGCT cis rs4665809 1.000 rs4665821 chr2:26309949 A/C cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs7552404 0.655 rs5745336 chr1:76273519 G/A cg10523679 chr1:76189770 ACADM 0.75 7.21 0.54 4.89e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1218582 0.596 rs4845676 chr1:154827861 C/G cg09359103 chr1:154839909 KCNN3 -0.51 -7.92 -0.58 1.15e-12 Prostate cancer; TGCT cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg25767906 chr1:53392781 SCP2 0.6 7.21 0.54 4.89e-11 Monocyte count; TGCT cis rs8103278 1.000 rs9807819 chr19:46239598 C/T cg14061069 chr19:46274453 DMPK -0.42 -6.06 -0.48 1.48e-8 Coronary artery disease; TGCT cis rs1045714 0.895 rs4719594 chr7:2639790 G/A cg17215154 chr7:2644645 IQCE 0.28 4.97 0.41 2.2e-6 Urate levels in lean individuals; TGCT cis rs11577318 0.538 rs10902745 chr1:26687070 G/C cg14210634 chr1:25870291 LDLRAP1 0.53 4.68 0.39 7.24e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs57920188 0.640 rs4311852 chr1:4085353 C/A cg20703997 chr1:4087676 NA 0.42 4.88 0.4 3.16e-6 Interleukin-17 levels; TGCT cis rs873946 0.586 rs12782567 chr10:134576709 C/G cg26818010 chr10:134567672 INPP5A 0.36 5.09 0.42 1.31e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6933660 0.665 rs6921042 chr6:151732385 T/C cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.62 0.38 9.63e-6 Menarche (age at onset); TGCT cis rs4253772 0.591 rs12167567 chr22:46659942 G/C cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.57 4.48 0.37 1.69e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs1372520 0.684 rs2737010 chr4:90746466 G/A cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs2229238 0.915 rs7514452 chr1:154438084 C/T cg13067139 chr1:155221277 FAM189B -0.2 -4.75 -0.39 5.6e-6 Coronary heart disease; TGCT cis rs16958440 0.867 rs16949275 chr18:44700703 A/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs2836974 0.897 rs1541102 chr21:40628765 C/T cg17971929 chr21:40555470 PSMG1 0.97 9.6 0.65 1.18e-16 Cognitive function; TGCT cis rs752092 0.855 rs7171515 chr15:101769618 C/T cg19997662 chr15:101784653 CHSY1 -0.27 -4.85 -0.4 3.69e-6 Corneal structure; TGCT cis rs12048904 0.619 rs10783153 chr1:101328230 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.69 5.64 0.45 1.1e-7 Multiple sclerosis; TGCT cis rs12950390 0.548 rs62076098 chr17:45860584 C/T cg06532163 chr17:45867833 NA 0.27 4.81 0.4 4.31e-6 IgG glycosylation; TGCT cis rs7659604 0.539 rs1507995 chr4:122748308 G/A cg20573242 chr4:122745356 CCNA2 0.64 5.6 0.45 1.29e-7 Type 2 diabetes; TGCT cis rs2932538 0.614 rs6537741 chr1:113085175 A/C cg22162597 chr1:113214053 CAPZA1 -0.22 -4.54 -0.38 1.32e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs10504229 0.639 rs2318145 chr8:58114867 A/G cg08280861 chr8:58055591 NA 0.4 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs11031096 0.678 rs1442727 chr11:4188188 G/T cg18678763 chr11:4115507 RRM1 0.46 6.02 0.48 1.81e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1348850 0.750 rs13031008 chr2:178477114 G/A cg22681709 chr2:178499509 PDE11A -0.48 -5.77 -0.46 6.03e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Vitiligo; TGCT cis rs9473924 0.505 rs2223869 chr6:50904239 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT trans rs4512344 0.510 rs35181953 chr8:11435049 G/A cg06636001 chr8:8085503 FLJ10661 -0.75 -6.9 -0.53 2.33e-10 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9952991 0.622 rs547268 chr18:12823056 G/T cg23598886 chr18:12777645 NA 0.54 4.74 0.39 5.88e-6 Inflammatory skin disease; TGCT cis rs67478160 0.643 rs2887282 chr14:104280734 A/G cg26031613 chr14:104095156 KLC1 -0.6 -6.06 -0.48 1.52e-8 Schizophrenia; TGCT cis rs2239547 0.522 rs6771610 chr3:53026104 T/C cg10802521 chr3:52805072 NEK4 -0.58 -5.31 -0.43 4.8e-7 Schizophrenia; TGCT cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg08280861 chr8:58055591 NA 0.54 5.98 0.47 2.17e-8 Developmental language disorder (linguistic errors); TGCT cis rs6484504 0.532 rs12788257 chr11:31255045 T/C cg26647111 chr11:31128758 NA -0.35 -4.86 -0.4 3.44e-6 Red blood cell count; TGCT cis rs8026198 0.517 rs8024113 chr15:42686838 G/C cg23803468 chr15:43513504 EPB42 0.3 4.51 0.38 1.5e-5 Fibrinogen levels; TGCT cis rs2562456 0.724 rs58001930 chr19:21742863 C/T cg01304269 chr19:21688519 ZNF429 0.56 4.69 0.39 6.99e-6 Pain; TGCT cis rs12477438 0.520 rs11692699 chr2:99730657 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs4700695 0.614 rs42321 chr5:65220342 G/A cg21114390 chr5:65439923 SFRS12 0.64 4.61 0.38 9.9e-6 Facial morphology (factor 19); TGCT cis rs5769765 1.000 rs761879 chr22:50241210 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 12.19 0.74 5.93e-23 Schizophrenia; TGCT cis rs6089584 0.893 rs6089306 chr20:60574868 G/A cg13770153 chr20:60521292 NA -0.53 -6.98 -0.53 1.58e-10 Body mass index; TGCT cis rs854765 0.647 rs9303144 chr17:17977355 T/C cg04398451 chr17:18023971 MYO15A -0.37 -6.18 -0.49 8.32e-9 Total body bone mineral density; TGCT cis rs7949030 0.591 rs35156678 chr11:62369881 G/A cg11742103 chr11:62369870 EML3;MTA2 0.61 8.75 0.62 1.29e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3733585 0.673 rs6814664 chr4:9956228 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9325144 0.671 rs35817541 chr12:38975001 T/C cg10518543 chr12:38710700 ALG10B -0.49 -4.68 -0.39 7.26e-6 Morning vs. evening chronotype; TGCT cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.71 7.58 0.56 6.92e-12 Blood metabolite levels; TGCT cis rs7513165 1.000 rs7513165 chr1:204147186 C/T cg04791601 chr1:204159016 NA -0.27 -5.51 -0.44 1.96e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT trans rs4512344 0.510 rs35181953 chr8:11435049 G/A cg15556689 chr8:8085844 FLJ10661 -0.77 -7.22 -0.54 4.68e-11 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs453301 0.686 rs6987107 chr8:8893581 A/G cg06636001 chr8:8085503 FLJ10661 -0.66 -5.58 -0.45 1.42e-7 Joint mobility (Beighton score); TGCT cis rs587847 0.708 rs1568449 chr15:37631589 C/T cg00216138 chr15:37171175 LOC145845 0.31 4.66 0.39 7.96e-6 Intraocular pressure; TGCT cis rs35883536 0.647 rs10875314 chr1:101043207 G/C cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.1e-12 Monocyte count; TGCT cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg10047753 chr17:41438598 NA 0.95 9.0 0.63 3.2e-15 Menopause (age at onset); TGCT cis rs9926296 0.744 rs164747 chr16:89708680 T/G cg03388025 chr16:89894329 SPIRE2 -0.34 -5.17 -0.42 9.17e-7 Vitiligo; TGCT cis rs1878931 0.501 rs9921169 chr16:3421261 A/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.12 0.54 7.59e-11 Body mass index (adult); TGCT cis rs7432375 0.610 rs56163507 chr3:136516056 C/T cg15507776 chr3:136538369 TMEM22 0.55 5.64 0.45 1.1e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs79349575 0.783 rs4294857 chr17:46983391 G/A cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT cis rs11785693 0.862 rs62491196 chr8:4995690 C/T cg26367366 chr8:4980734 NA 0.58 4.45 0.37 1.91e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg02953382 chr22:24373134 LOC391322 -0.74 -7.56 -0.56 7.77e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11122272 0.735 rs910824 chr1:231498773 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.63 -0.51 9.1e-10 Hemoglobin concentration; TGCT cis rs3924048 0.574 rs11121930 chr1:12616956 C/A cg00291366 chr1:12616550 NA 0.33 5.14 0.42 1.05e-6 Optic cup area; TGCT cis rs7959452 0.535 rs4761228 chr12:69682327 G/A cg14784868 chr12:69753453 YEATS4 0.68 6.95 0.53 1.87e-10 Blood protein levels; TGCT cis rs1784581 0.588 rs9346894 chr6:162430763 T/C cg17173639 chr6:162384350 PARK2 0.4 6.68 0.51 7.34e-10 Itch intensity from mosquito bite; TGCT cis rs2637266 1.000 rs7914880 chr10:78363693 A/G cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg08280861 chr8:58055591 NA 0.36 4.98 0.41 2.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg19774624 chr17:42201019 HDAC5 -0.85 -10.09 -0.67 7.79e-18 Total body bone mineral density; TGCT cis rs7726839 0.561 rs72703050 chr5:582917 A/C cg09021430 chr5:549028 NA -0.37 -5.23 -0.42 7.12e-7 Obesity-related traits; TGCT cis rs4812048 1.000 rs6070697 chr20:57599402 G/A cg24457521 chr20:57607420 ATP5E -0.67 -4.59 -0.38 1.05e-5 Mean platelet volume; TGCT cis rs9894429 0.608 rs8477 chr17:79618059 C/T cg21028142 chr17:79581711 NPLOC4 0.28 5.83 0.46 4.52e-8 Eye color traits; TGCT cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg17264618 chr3:40429014 ENTPD3 -0.32 -4.76 -0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs6964587 0.967 rs10279943 chr7:91587477 G/C cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg11965913 chr1:205819406 PM20D1 0.6 9.43 0.65 3.09e-16 Menarche (age at onset); TGCT cis rs1609391 0.543 rs7651085 chr3:136625339 C/G cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs4654899 0.931 rs4654726 chr1:21203898 A/C cg01072550 chr1:21505969 NA 0.49 7.75 0.57 2.82e-12 Superior frontal gyrus grey matter volume; TGCT cis rs4512344 0.514 rs13255193 chr8:11309192 T/C cg21775007 chr8:11205619 TDH -0.5 -4.85 -0.4 3.61e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs6089829 0.926 rs1060491 chr20:61665817 C/A cg08045932 chr20:61659980 NA -0.44 -7.89 -0.58 1.39e-12 Prostate cancer (SNP x SNP interaction); TGCT cis rs1992660 0.510 rs6889125 chr5:40412590 A/T cg01087697 chr5:40835557 RPL37 0.55 4.96 0.41 2.25e-6 Crohn's disease; TGCT cis rs1371867 0.846 rs1660324 chr8:101281271 C/T cg06002616 chr8:101225028 SPAG1 -0.57 -6.77 -0.52 4.48e-10 Atrioventricular conduction; TGCT cis rs10746514 0.841 rs9725652 chr1:232245997 T/A cg09506761 chr1:232265262 NA 0.46 4.71 0.39 6.41e-6 Response to statin therapy; TGCT cis rs986417 0.901 rs1950313 chr14:60997782 A/G cg27398547 chr14:60952738 C14orf39 1.51 10.28 0.68 2.67e-18 Gut microbiota (bacterial taxa); TGCT cis rs2594989 0.780 rs2454477 chr3:11555842 G/A cg00170343 chr3:11313890 ATG7 0.63 4.47 0.37 1.77e-5 Circulating chemerin levels; TGCT cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg23283495 chr1:209979779 IRF6 0.67 5.7 0.46 8.12e-8 Cleft lip with or without cleft palate; TGCT cis rs6500602 0.627 rs709632 chr16:4587811 C/G cg08645402 chr16:4508243 NA -0.21 -5.51 -0.44 2e-7 Schizophrenia; TGCT cis rs9467773 1.000 rs6940188 chr6:26562029 G/C cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg12310025 chr6:25882481 NA 0.7 6.44 0.5 2.4e-9 Intelligence (multi-trait analysis); TGCT cis rs992157 0.710 rs10167446 chr2:219056866 A/G cg00012203 chr2:219082015 ARPC2 0.84 10.71 0.69 2.41e-19 Colorectal cancer; TGCT cis rs7552404 0.691 rs1770890 chr1:76401117 A/G cg03433033 chr1:76189801 ACADM -0.74 -7.49 -0.56 1.14e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.830 rs7682991 chr4:98982595 C/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs17221829 0.733 rs72971009 chr11:89358840 A/G cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs2456568 0.802 rs10765638 chr11:93636171 A/T cg14065697 chr11:93583672 C11orf90 -0.37 -4.63 -0.38 9.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2734839 0.537 rs6277 chr11:113283459 G/A cg14159747 chr11:113255604 NA 0.38 4.8 0.4 4.51e-6 Information processing speed; TGCT cis rs11190604 1.000 rs10883503 chr10:102275504 C/A cg23241863 chr10:102295624 HIF1AN 0.71 5.36 0.43 3.87e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1153858 1.000 rs2056493 chr15:45648272 A/G cg14582100 chr15:45693742 SPATA5L1 0.47 5.65 0.45 1.04e-7 Homoarginine levels; TGCT cis rs2153535 0.580 rs1335637 chr6:8465101 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1865760 0.820 rs9348697 chr6:25890834 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.62 5.75 0.46 6.49e-8 Height; TGCT cis rs9926296 0.605 rs12448860 chr16:89849629 T/A cg21285383 chr16:89894308 SPIRE2 0.47 7.4 0.55 1.83e-11 Vitiligo; TGCT cis rs6570726 0.764 rs448258 chr6:145869145 C/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6570726 0.791 rs9399558 chr6:145911730 T/C cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1395 0.778 rs2580759 chr2:27432500 G/T cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.64 -8.71 -0.62 1.61e-14 Blood metabolite levels; TGCT cis rs12142240 0.698 rs1057533 chr1:46815836 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1008375 0.966 rs1860599 chr4:17638900 T/C cg16339924 chr4:17578868 LAP3 0.66 5.49 0.44 2.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4478858 0.647 rs4949380 chr1:31764160 A/G cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs12681288 0.550 rs6989880 chr8:957209 A/G cg04851639 chr8:1020857 NA -0.27 -4.45 -0.37 1.85e-5 Schizophrenia; TGCT cis rs10255878 0.568 rs77330846 chr7:97041183 T/C cg01534613 chr7:96337050 SHFM1 0.29 4.53 0.38 1.39e-5 Adverse response to radiation therapy; TGCT cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9682041 0.932 rs9841852 chr3:170067049 C/G cg07589077 chr3:170072950 NA 0.34 5.14 0.42 1.03e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs4700695 0.841 rs152933 chr5:65359530 A/G cg21114390 chr5:65439923 SFRS12 -0.61 -4.55 -0.38 1.24e-5 Facial morphology (factor 19); TGCT cis rs587847 0.737 rs17443613 chr15:37665895 C/T cg00216138 chr15:37171175 LOC145845 0.31 4.53 0.38 1.38e-5 Intraocular pressure; TGCT cis rs9611565 0.506 rs2024566 chr22:41697338 A/G cg03806693 chr22:41940476 POLR3H -0.82 -7.85 -0.58 1.7e-12 Vitiligo; TGCT cis rs807669 0.525 rs9605955 chr22:19181557 C/T cg02655711 chr22:19163373 SLC25A1 0.25 4.61 0.38 9.87e-6 Metabolite levels; TGCT cis rs9611565 0.512 rs5758464 chr22:42171300 A/G cg06481639 chr22:41940642 POLR3H 0.79 5.3 0.43 5.16e-7 Vitiligo; TGCT cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg01448562 chr3:133502909 NA -0.35 -7.23 -0.54 4.43e-11 Iron status biomarkers; TGCT cis rs7584330 0.780 rs7582828 chr2:238378476 A/C cg14458575 chr2:238380390 NA -0.5 -7.96 -0.58 9.28e-13 Prostate cancer; TGCT cis rs2842992 0.673 rs6930904 chr6:160217433 T/A cg11366901 chr6:160182831 ACAT2 1.06 7.18 0.54 5.54e-11 Age-related macular degeneration (geographic atrophy); TGCT cis rs7089973 0.525 rs11196945 chr10:116600424 G/A cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs477895 0.838 rs1058735 chr11:64000410 C/G cg23719950 chr11:63933701 MACROD1 -0.68 -5.65 -0.45 1.07e-7 Mean platelet volume; TGCT cis rs6121246 0.909 rs6119720 chr20:30347568 T/G cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs910316 0.934 rs4903278 chr14:75535019 C/A cg11812906 chr14:75593930 NEK9 0.73 7.08 0.54 9.58e-11 Height; TGCT cis rs28595532 0.841 rs115209862 chr4:119742225 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2439831 0.681 rs524527 chr15:43599116 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.91 -6.54 -0.51 1.43e-9 Lung cancer in ever smokers; TGCT cis rs9318086 0.648 rs9507184 chr13:24473642 T/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.82 8.98 0.63 3.58e-15 Myopia (pathological); TGCT cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs7017914 0.905 rs2639957 chr8:71923202 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.2e-6 Bone mineral density; TGCT cis rs2506889 0.553 rs17035189 chr1:10597024 A/G cg17425144 chr1:10567563 PEX14 0.53 7.58 0.56 6.96e-12 Breast cancer; TGCT cis rs916888 0.773 rs199533 chr17:44828931 G/A cg15921436 chr17:44337874 NA 0.55 7.61 0.56 5.9e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4253772 0.614 rs11090859 chr22:46687460 T/G cg24881330 chr22:46731750 TRMU 0.95 6.23 0.49 6.65e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs6920965 0.545 rs2326242 chr6:126174859 A/C cg05901451 chr6:126070800 HEY2 -0.58 -5.11 -0.42 1.16e-6 High light scatter reticulocyte count; TGCT cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 4.69 0.39 7.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs17767294 0.708 rs76223516 chr6:27939475 C/T cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs3806843 0.547 rs246033 chr5:140332115 A/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs13418410 0.539 rs11695597 chr2:33840024 A/G cg04131969 chr2:33951647 MYADML 0.78 7.67 0.57 4.47e-12 Non-response to antidepressants and depression; TGCT cis rs6087990 0.735 rs2424907 chr20:31359819 C/T cg13636640 chr20:31349939 DNMT3B 0.92 11.89 0.73 3.16e-22 Ulcerative colitis; TGCT cis rs10484885 0.824 rs11967579 chr6:90540008 G/T cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6964587 1.000 rs9784993 chr7:91672403 G/A cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs763121 0.962 rs909564 chr22:39126508 A/G cg06022373 chr22:39101656 GTPBP1 0.69 6.58 0.51 1.21e-9 Menopause (age at onset); TGCT cis rs12220238 1.000 rs12256105 chr10:75909634 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs8180040 0.620 rs56217494 chr3:47048452 T/G cg27129171 chr3:47204927 SETD2 -0.7 -8.36 -0.6 1.09e-13 Colorectal cancer; TGCT cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs7582180 0.629 rs12620139 chr2:100943446 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.772 rs4845689 chr1:154885524 A/G cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg18765753 chr7:1198926 ZFAND2A -0.53 -6.65 -0.51 8.22e-10 Longevity;Endometriosis; TGCT cis rs17221829 0.673 rs12364712 chr11:89373847 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs4733781 0.509 rs7008182 chr8:131344745 T/A cg16277922 chr8:131349729 ASAP1 -0.53 -8.77 -0.62 1.14e-14 Tuberculosis; TGCT cis rs6922617 0.685 rs56902797 chr6:41349029 G/A cg07798131 chr6:41471673 NA 0.89 4.46 0.37 1.82e-5 Alzheimer's disease biomarkers; TGCT cis rs8177253 0.965 rs4854762 chr3:133499063 A/G cg11941060 chr3:133502564 NA 0.28 6.07 0.48 1.42e-8 Iron status biomarkers; TGCT cis rs9811216 1.000 rs6793295 chr3:169518455 T/C cg08193579 chr3:169529701 LRRC34 0.3 4.59 0.38 1.05e-5 Neutrophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs12220238 1.000 rs11000931 chr10:75984800 A/C cg19889307 chr10:75911429 ADK;AP3M1 -1.06 -8.04 -0.59 6.03e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1371867 0.875 rs962451 chr8:101331010 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs6450176 0.859 rs3776719 chr5:53298684 T/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2075371 1.000 rs8134 chr7:133974519 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.68e-9 Mean platelet volume; TGCT cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT trans rs57221529 0.709 rs72706612 chr5:561198 C/T cg11887960 chr12:57824829 NA 1.16 9.59 0.65 1.25e-16 Lung disease severity in cystic fibrosis; TGCT cis rs12530845 1.000 rs4291211 chr7:135335373 C/T cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg24503407 chr1:205819492 PM20D1 0.67 10.31 0.68 2.24e-18 Menarche (age at onset); TGCT cis rs7824557 0.628 rs6601580 chr8:11193736 T/G cg21775007 chr8:11205619 TDH 0.7 6.86 0.52 2.93e-10 Retinal vascular caliber; TGCT cis rs11122272 0.735 rs2491410 chr1:231532287 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.74 -7.35 -0.55 2.3e-11 Hemoglobin concentration; TGCT cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg09704166 chr2:114031854 PAX8;LOC440839 -0.32 -4.82 -0.4 4.04e-6 Lymphocyte counts; TGCT cis rs981844 0.890 rs55850399 chr4:154684906 C/T cg14289246 chr4:154710475 SFRP2 1.05 9.32 0.64 5.44e-16 Response to statins (LDL cholesterol change); TGCT cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs7666738 0.830 rs6532715 chr4:99016792 G/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3087591 0.960 rs8080679 chr17:29602610 A/G cg24425628 chr17:29625626 OMG;NF1 0.47 7.21 0.54 4.8e-11 Hip circumference; TGCT cis rs9467773 1.000 rs6924838 chr6:26571756 C/T cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs2956278 0.717 rs2947129 chr12:84690270 T/A cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs3806933 0.522 rs11241095 chr5:110439509 A/G cg04022379 chr5:110408740 TSLP 0.6 6.19 0.49 8.19e-9 Eosinophilic esophagitis; TGCT cis rs709400 0.627 rs55859054 chr14:103953666 T/A cg12935359 chr14:103987150 CKB -0.37 -5.53 -0.44 1.81e-7 Body mass index; TGCT cis rs12510870 0.599 rs56384466 chr4:74388990 T/C cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs7119 0.689 rs12907630 chr15:77812906 G/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.55 -0.38 1.26e-5 Type 2 diabetes; TGCT cis rs11822910 0.911 rs11828218 chr11:57196223 C/G cg00522883 chr11:57194120 SLC43A3 0.31 4.54 0.38 1.3e-5 Platelet distribution width; TGCT trans rs1005277 0.579 rs2472181 chr10:38386764 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs6076065 1.000 rs2405231 chr20:23342239 A/C cg11657817 chr20:23433608 CST11 0.28 4.55 0.38 1.25e-5 Facial morphology (factor 15, philtrum width); TGCT cis rs7119 0.717 rs12910594 chr15:77817103 G/A cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs3749237 0.595 rs3870337 chr3:49557095 G/T cg07636037 chr3:49044803 WDR6 0.62 5.83 0.46 4.59e-8 Resting heart rate; TGCT cis rs2816062 0.786 rs2745316 chr1:18896830 G/A cg18795169 chr1:18902165 NA -0.61 -14.28 -0.79 6.04e-28 Urate levels in lean individuals; TGCT cis rs3733585 0.673 rs9993410 chr4:9951264 C/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.46 -0.5 2.14e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4699052 0.507 rs10005997 chr4:104301711 C/G cg16532752 chr4:104119610 CENPE -0.74 -6.22 -0.49 6.95e-9 Testicular germ cell tumor; TGCT cis rs67073037 0.915 rs12622793 chr2:29111106 C/T cg09522027 chr2:28974177 PPP1CB 0.58 4.48 0.37 1.69e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs6882046 0.513 rs639725 chr5:88001969 A/G cg22951263 chr5:87985283 NA -0.61 -6.53 -0.51 1.49e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs36051895 0.664 rs7852755 chr9:5100862 C/T cg02405213 chr9:5042618 JAK2 -0.76 -10.67 -0.69 3.05e-19 Pediatric autoimmune diseases; TGCT cis rs1568889 0.838 rs716366 chr11:28121536 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.9 10.84 0.7 1.12e-19 Bipolar disorder; TGCT cis rs9796 0.840 rs1009913 chr15:41331050 C/T cg18705301 chr15:41695430 NDUFAF1 0.41 5.17 0.42 9.27e-7 Menopause (age at onset); TGCT cis rs4911259 0.552 rs6058925 chr20:31465374 G/A cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg26354017 chr1:205819088 PM20D1 0.67 8.86 0.62 7.19e-15 Menarche (age at onset); TGCT cis rs4665809 0.589 rs4665841 chr2:26448950 G/A cg22920501 chr2:26401640 FAM59B -0.81 -6.42 -0.5 2.63e-9 Gut microbiome composition (summer); TGCT cis rs2274459 0.841 rs12203688 chr6:33693624 G/T cg00898486 chr6:34006557 GRM4 -0.29 -4.64 -0.38 8.74e-6 Obesity (extreme); TGCT cis rs6728642 0.572 rs13403225 chr2:97600827 A/G cg26665480 chr2:98280029 ACTR1B -0.91 -7.03 -0.53 1.2e-10 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs3751972 0.911 rs11657613 chr17:26252856 T/C cg02948944 chr17:26242737 NA 0.5 6.86 0.52 2.9e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs4851266 0.898 rs12053126 chr2:100864646 A/T cg22139774 chr2:100720529 AFF3 -0.35 -5.51 -0.44 1.99e-7 Educational attainment; TGCT cis rs854765 0.583 rs11078404 chr17:17820487 A/T cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.83e-6 Total body bone mineral density; TGCT cis rs7845219 0.544 rs34208552 chr8:95908067 C/G cg13393036 chr8:95962371 TP53INP1 -0.45 -5.16 -0.42 9.7e-7 Type 2 diabetes; TGCT cis rs12477438 0.520 rs12621007 chr2:99791946 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.32 0.85 4.52e-37 Chronic sinus infection; TGCT cis rs2760061 0.598 rs658238 chr1:228121291 A/G cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs6089829 0.888 rs4809468 chr20:61673566 T/C cg03213289 chr20:61660250 NA 0.73 9.58 0.65 1.31e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs9948 0.655 rs6758151 chr2:97388884 A/G cg01990225 chr2:97406019 LMAN2L -0.94 -5.33 -0.43 4.44e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs57244997 0.872 rs11759694 chr6:162405705 C/G cg17173639 chr6:162384350 PARK2 0.44 4.78 0.39 4.79e-6 Mosquito bite size; TGCT cis rs9583531 1.000 rs9583531 chr13:111385161 T/G cg24331049 chr13:111365604 ING1 -0.77 -5.5 -0.44 2.1e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs10025174 chr4:98914172 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.2 0.54 5.03e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1215050 0.791 rs783960 chr4:98893437 A/G cg17366294 chr4:99064904 C4orf37 -0.53 -5.69 -0.45 8.67e-8 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs17685 0.712 rs6464994 chr7:75784668 C/T cg19862616 chr7:65841803 NCRNA00174 0.53 9.19 0.64 1.13e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6840360 0.571 rs62327268 chr4:152522326 T/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs2766547 0.647 rs2766542 chr6:35707690 A/G cg01618151 chr6:35707957 C6orf81 -0.27 -4.52 -0.38 1.42e-5 Eosinophil percentage of granulocytes; TGCT trans rs7615952 1.000 rs7615952 chr3:125649403 A/C cg07211511 chr3:129823064 LOC729375 0.46 7.6 0.56 6.4e-12 Blood pressure (smoking interaction); TGCT cis rs112217694 1.000 rs17249126 chr4:104653263 A/G cg24090629 chr4:104641072 TACR3 0.97 4.81 0.4 4.25e-6 Menarche (age at onset); TGCT cis rs72949976 0.678 rs7573232 chr2:214040425 C/T cg08319019 chr2:214017104 IKZF2 -0.72 -5.98 -0.47 2.17e-8 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs611744 0.935 rs661036 chr8:109213088 C/T cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs2456568 0.709 rs7942444 chr11:93637160 G/A cg17595323 chr11:93583763 C11orf90 0.46 5.96 0.47 2.39e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3087591 0.821 rs1034705 chr17:29536133 C/G cg24425628 chr17:29625626 OMG;NF1 -0.46 -7.13 -0.54 7.14e-11 Hip circumference; TGCT cis rs2180341 0.513 rs12196828 chr6:127696864 C/T cg27446573 chr6:127587934 RNF146 0.67 6.07 0.48 1.41e-8 Breast cancer; TGCT cis rs7098414 0.511 rs4934134 chr10:82160582 C/T cg01528321 chr10:82214614 TSPAN14 0.56 4.98 0.41 2.07e-6 Post bronchodilator FEV1; TGCT cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs4077515 0.874 rs4498662 chr9:139290251 C/G cg13741927 chr9:139327495 INPP5E -0.19 -4.63 -0.38 9.06e-6 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs7267979 0.868 rs6107019 chr20:25233985 C/T cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg24675658 chr1:53192096 ZYG11B 0.85 10.97 0.7 5.36e-20 Monocyte count; TGCT cis rs796364 0.625 rs4673837 chr2:201131159 A/G cg23649088 chr2:200775458 C2orf69 0.33 4.44 0.37 1.99e-5 Schizophrenia; TGCT cis rs3087591 0.639 rs2342053 chr17:29722196 A/G cg24425628 chr17:29625626 OMG;NF1 0.4 5.85 0.47 4.05e-8 Hip circumference; TGCT cis rs62225284 1.000 rs62225284 chr22:47572322 T/C cg18621123 chr22:47569642 TBC1D22A 0.26 5.21 0.42 7.65e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT trans rs2727020 0.553 rs11040400 chr11:49518296 C/A cg03929089 chr4:120376271 NA -0.66 -7.62 -0.56 5.75e-12 Coronary artery disease; TGCT cis rs78487399 0.808 rs13395290 chr2:43706319 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.96 -0.41 2.24e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs56235845 0.685 rs35630910 chr5:176757841 A/C cg16006841 chr5:176797999 RGS14 0.54 7.87 0.58 1.53e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs875971 0.965 rs28682868 chr7:65689809 C/T cg18876405 chr7:65276391 NA -0.32 -4.92 -0.4 2.72e-6 Aortic root size; TGCT cis rs910316 1.000 rs11845639 chr14:75570293 C/T cg11812906 chr14:75593930 NEK9 0.75 7.4 0.55 1.77e-11 Height; TGCT cis rs12908161 1.000 rs36033486 chr15:85319692 A/G cg12863693 chr15:85201151 NMB 0.43 5.12 0.42 1.15e-6 Schizophrenia; TGCT cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg03806693 chr22:41940476 POLR3H 1.15 13.16 0.76 2.69e-25 Vitiligo; TGCT cis rs11098499 0.954 rs11935596 chr4:120412457 G/C cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs10838634 1.000 rs7108147 chr11:46830847 G/A cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs17152411 0.895 rs3940439 chr10:126584531 C/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs7267979 0.932 rs928121 chr20:25534818 A/G cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5750830 0.569 rs5750809 chr22:39791491 T/G cg01416388 chr22:39784598 NA -0.72 -7.05 -0.53 1.1e-10 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.723 rs57216949 chr7:2030287 G/T cg22963979 chr7:1858916 MAD1L1 -0.45 -7.41 -0.55 1.74e-11 Bipolar disorder and schizophrenia; TGCT cis rs2439831 0.850 rs7169322 chr15:44131014 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT cis rs2485376 0.842 rs11597439 chr10:104184953 C/G cg26089160 chr10:104170217 PSD 0.51 5.04 0.41 1.62e-6 QT interval; TGCT cis rs2404602 0.692 rs12913810 chr15:77166675 T/C cg22467129 chr15:76604101 ETFA -0.47 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs2862064 1.000 rs9313405 chr5:156447750 T/C cg12943317 chr5:156479607 HAVCR1 -0.36 -4.99 -0.41 1.97e-6 Platelet count; TGCT cis rs997781 0.611 rs8080863 chr17:67169500 A/G cg21660392 chr17:66950545 ABCA8 -0.29 -4.45 -0.37 1.91e-5 MGMT methylation in smokers; TGCT cis rs11098499 0.863 rs1010739 chr4:120463471 C/T cg09307838 chr4:120376055 NA 0.6 5.22 0.42 7.16e-7 Corneal astigmatism; TGCT cis rs698813 0.572 rs12613771 chr2:44490660 C/A cg00619915 chr2:44497795 NA -0.24 -5.54 -0.45 1.75e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs5769707 0.777 rs739243 chr22:50057211 C/T cg20744362 chr22:50050164 C22orf34 0.29 4.68 0.39 7.3e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs11650494 0.908 rs11658111 chr17:47383994 C/T cg08112188 chr17:47440006 ZNF652 1.04 5.31 0.43 4.88e-7 Prostate cancer; TGCT cis rs7666738 0.791 rs10033211 chr4:98995624 T/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg16414030 chr3:133502952 NA -0.5 -7.03 -0.53 1.2e-10 Iron status biomarkers; TGCT cis rs9926296 0.585 rs4785595 chr16:89835521 C/T cg03388025 chr16:89894329 SPIRE2 -0.49 -8.61 -0.61 2.79e-14 Vitiligo; TGCT cis rs7474896 0.609 rs11011336 chr10:37985316 A/G cg13720705 chr10:37990370 NA 0.34 5.03 0.41 1.71e-6 Obesity (extreme); TGCT cis rs10936602 0.527 rs9814802 chr3:169532377 A/G cg08193579 chr3:169529701 LRRC34 0.29 5.33 0.43 4.38e-7 Renal cell carcinoma; TGCT cis rs40363 0.645 rs250633 chr16:3523002 C/T cg21433313 chr16:3507492 NAT15 0.37 4.83 0.4 3.95e-6 Tuberculosis; TGCT cis rs6582630 0.519 rs1851130 chr12:38507819 C/T cg13010199 chr12:38710504 ALG10B 0.59 4.83 0.4 4.02e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg21724239 chr8:58056113 NA 0.5 5.43 0.44 2.83e-7 Developmental language disorder (linguistic errors); TGCT cis rs73198271 0.694 rs113694763 chr8:8647076 C/T cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7805747 0.961 rs10254101 chr7:151415536 C/T cg17611936 chr7:151411526 PRKAG2 0.54 6.72 0.52 5.9e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs1891275 0.550 rs4933694 chr10:93499213 C/T cg07889827 chr10:93443413 NA -0.33 -6.94 -0.53 1.97e-10 Intelligence (multi-trait analysis); TGCT cis rs8026198 0.929 rs2407707 chr15:42659350 G/A cg20699549 chr15:42567973 GANC 0.23 4.44 0.37 1.98e-5 Fibrinogen levels; TGCT cis rs539096 0.749 rs12076635 chr1:44026656 G/C cg12908607 chr1:44402522 ARTN -0.52 -5.4 -0.44 3.3e-7 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.659 rs12602808 chr17:56698420 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg03806693 chr22:41940476 POLR3H -1.07 -11.31 -0.71 8.12e-21 Vitiligo; TGCT cis rs7635838 0.822 rs9861633 chr3:11473437 C/G cg00170343 chr3:11313890 ATG7 0.66 6.34 0.49 3.87e-9 HDL cholesterol; TGCT cis rs2305707 0.605 rs76084537 chr15:51553278 G/A cg19946085 chr15:51559439 CYP19A1 0.49 5.15 0.42 9.79e-7 Height; TGCT cis rs2204008 0.740 rs1283308 chr12:38154565 C/T cg26384229 chr12:38710491 ALG10B -0.57 -4.9 -0.4 2.99e-6 Bladder cancer; TGCT trans rs1005277 0.579 rs1614236 chr10:38502996 C/T cg27523141 chr10:43048294 ZNF37B 0.71 8.26 0.6 1.84e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6988636 1.000 rs11992152 chr8:124189455 T/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs9329221 0.870 rs11777976 chr8:10255402 A/G cg21775007 chr8:11205619 TDH -0.53 -4.8 -0.4 4.5e-6 Neuroticism; TGCT cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg20607798 chr8:58055168 NA 0.49 4.78 0.39 4.9e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.861 rs11206026 chr1:53281708 G/A cg01802117 chr1:53393560 SCP2 -0.4 -4.83 -0.4 3.92e-6 Monocyte count; TGCT cis rs1903068 0.719 rs17711225 chr4:55999185 G/A cg09978860 chr4:56023921 NA 0.56 5.89 0.47 3.34e-8 Endometriosis; TGCT cis rs858239 0.601 rs6969733 chr7:23168377 T/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.18 -0.42 8.52e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2354432 0.607 rs59606861 chr1:146761478 G/A cg25205988 chr1:146714368 CHD1L -1.35 -5.85 -0.46 4.18e-8 Mitochondrial DNA levels; TGCT cis rs1670533 1.000 rs62294756 chr4:1097676 G/A cg27284194 chr4:1044797 NA -0.69 -6.07 -0.48 1.45e-8 Recombination rate (females); TGCT trans rs1814175 0.588 rs1794144 chr11:49918233 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs2013441 0.965 rs8071665 chr17:20209943 T/C cg23224458 chr17:20280056 CCDC144C -0.41 -4.88 -0.4 3.25e-6 Obesity-related traits; TGCT cis rs910316 0.737 rs108622 chr14:75481908 A/G cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.38e-7 Height; TGCT cis rs3749237 0.595 rs17595772 chr3:49409704 G/A cg07636037 chr3:49044803 WDR6 0.64 6.04 0.48 1.63e-8 Resting heart rate; TGCT cis rs916888 0.687 rs199456 chr17:44797919 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.78 5.34 0.43 4.36e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1395 0.778 rs11126918 chr2:27438710 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.37 0.64 4.22e-16 Blood metabolite levels; TGCT cis rs6582630 0.519 rs7294300 chr12:38277359 C/A cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs637571 0.522 rs7105628 chr11:65763067 C/T cg17985854 chr11:65770987 BANF1;EIF1AD 0.21 4.45 0.37 1.88e-5 Eosinophil percentage of white cells; TGCT cis rs10791323 0.592 rs2851115 chr11:133705381 C/A cg03690763 chr11:133734501 NA -0.35 -5.34 -0.43 4.31e-7 Childhood ear infection; TGCT cis rs1670533 1.000 rs652063 chr4:1084137 T/C cg27284194 chr4:1044797 NA 0.68 5.95 0.47 2.59e-8 Recombination rate (females); TGCT cis rs6430585 0.528 rs16832417 chr2:136744678 C/T cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs9549367 0.713 rs2476328 chr13:113829350 C/T cg00898013 chr13:113819073 PROZ 0.52 6.61 0.51 1.03e-9 Platelet distribution width; TGCT cis rs7010267 0.935 rs11573824 chr8:119959925 A/T cg17171407 chr8:119960777 TNFRSF11B 0.33 6.18 0.49 8.29e-9 Total body bone mineral density (age 45-60); TGCT cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs11711311 0.955 rs10934241 chr3:113394705 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -6.81 -0.52 3.79e-10 IgG glycosylation; TGCT cis rs2243480 1.000 rs34970380 chr7:65431493 C/T cg18252515 chr7:66147081 NA -1.22 -7.16 -0.54 6.34e-11 Diabetic kidney disease; TGCT cis rs4975709 0.589 rs4975745 chr5:1861058 G/C cg12288994 chr5:1860383 NA 0.24 4.72 0.39 6.2e-6 Cardiovascular disease risk factors; TGCT cis rs9916302 0.706 rs594794 chr17:37453485 T/C cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT trans rs3774749 0.565 rs2518796 chr3:50207075 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.81 7.96 0.58 9.46e-13 Intelligence (multi-trait analysis); TGCT cis rs9640161 0.750 rs1047575 chr7:150035500 C/G cg10018233 chr7:150070692 REPIN1 0.31 4.45 0.37 1.88e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs981844 0.775 rs62324020 chr4:154763851 G/A cg14289246 chr4:154710475 SFRP2 1.01 8.89 0.62 5.85e-15 Response to statins (LDL cholesterol change); TGCT cis rs7937840 0.581 rs4963286 chr11:61887232 C/A cg05871569 chr11:61891931 INCENP 0.69 6.4 0.5 2.91e-9 Breast cancer; TGCT cis rs35264875 0.950 rs35337391 chr11:68854012 A/G cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs35771425 0.642 rs11586974 chr1:211464115 A/G cg26515805 chr1:211431828 RCOR3 0.42 4.53 0.38 1.39e-5 Educational attainment (years of education); TGCT cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg00814883 chr7:100076585 TSC22D4 -0.82 -8.37 -0.6 1.03e-13 Platelet count; TGCT cis rs9302065 0.866 rs75006318 chr13:95968259 T/G cg26751094 chr13:95954534 ABCC4 -0.32 -5.3 -0.43 5.01e-7 Blood metabolite levels; TGCT cis rs877282 0.898 rs11253340 chr10:764786 G/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs9926296 0.585 rs1800337 chr16:89845194 A/G cg27121462 chr16:89883253 FANCA 0.78 8.31 0.6 1.45e-13 Vitiligo; TGCT cis rs4975709 0.610 rs4975706 chr5:1860365 G/T cg04156016 chr5:1868137 NA 0.33 4.63 0.38 9.04e-6 Cardiovascular disease risk factors; TGCT cis rs2742234 0.614 rs3026750 chr10:43607756 G/A cg02780029 chr10:43622663 RET -0.25 -4.96 -0.41 2.31e-6 Hirschsprung disease; TGCT cis rs7666738 0.830 rs28687737 chr4:99009226 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7524258 0.868 rs4908448 chr1:7269283 A/G cg07173049 chr1:7289937 CAMTA1 -0.28 -4.61 -0.38 9.88e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs769267 0.896 rs7253807 chr19:19631444 A/T cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg10047753 chr17:41438598 NA 0.96 9.54 0.65 1.61e-16 Menopause (age at onset); TGCT cis rs711830 1.000 rs1318778 chr2:177037831 C/G cg13092806 chr2:177043255 NA 0.77 5.92 0.47 2.92e-8 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs11096990 0.600 rs6835337 chr4:39282809 T/A cg20847110 chr4:39482781 LOC401127 -0.16 -4.53 -0.38 1.39e-5 Cognitive function; TGCT cis rs7666738 0.830 rs6827516 chr4:98971740 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1865760 0.566 rs3752420 chr6:26027135 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.44 0.56 1.47e-11 Height; TGCT cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg20637647 chr7:64974828 NA 0.9 5.15 0.42 9.9e-7 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs6854594 chr4:99065312 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs314370 0.951 rs12705092 chr7:100473550 G/A cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs35771425 0.619 rs6689078 chr1:211476423 C/G cg26515805 chr1:211431828 RCOR3 -0.46 -5.04 -0.41 1.6e-6 Educational attainment (years of education); TGCT cis rs3784262 0.692 rs3784256 chr15:58263046 T/A cg12031962 chr15:58353849 ALDH1A2 -0.41 -5.82 -0.46 4.7e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7169223 0.653 rs2904228 chr15:79086099 G/A cg21242079 chr15:79101063 ADAMTS7 -0.37 -5.93 -0.47 2.78e-8 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs28595532 0.841 rs55744948 chr4:119769243 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs3540 0.554 rs12443252 chr15:91064690 C/T cg22089800 chr15:90895588 ZNF774 -0.76 -8.06 -0.59 5.32e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs17253792 0.822 rs78386830 chr14:56069224 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs9653442 0.545 rs12712067 chr2:100763900 A/C cg22139774 chr2:100720529 AFF3 0.37 5.85 0.47 4.03e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2153535 0.601 rs2015281 chr6:8539673 G/A cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs6684514 0.922 rs12047994 chr1:156284535 C/A cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs926938 0.543 rs360600 chr1:115388116 T/C cg12756093 chr1:115239321 AMPD1 0.44 6.36 0.5 3.48e-9 Autism; TGCT cis rs595982 0.527 rs17206707 chr19:49361441 A/C cg21252483 chr19:49399788 TULP2 -0.43 -6.28 -0.49 5.27e-9 Red cell distribution width; TGCT cis rs7772486 0.875 rs13204280 chr6:146415368 T/C cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs57221529 0.563 rs4957057 chr5:569230 C/G cg25482853 chr8:67687455 SGK3 1.1 8.74 0.62 1.34e-14 Lung disease severity in cystic fibrosis; TGCT cis rs7659604 0.643 rs6839375 chr4:122663610 G/C cg19748678 chr4:122722346 EXOSC9 0.56 4.86 0.4 3.43e-6 Type 2 diabetes; TGCT cis rs7226408 1.000 rs72883547 chr18:34361227 C/T cg06757138 chr18:34340585 FHOD3 0.28 4.76 0.39 5.23e-6 Obesity-related traits; TGCT cis rs929354 0.685 rs7807856 chr7:156934498 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg16497277 chr3:49208875 KLHDC8B -0.55 -5.25 -0.43 6.31e-7 Menarche (age at onset); TGCT cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg17971929 chr21:40555470 PSMG1 -0.71 -6.76 -0.52 4.82e-10 Cognitive function; TGCT cis rs7091068 0.671 rs517785 chr10:95403973 G/A cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs636291 0.500 rs655271 chr1:10536635 G/A cg17425144 chr1:10567563 PEX14 0.53 7.34 0.55 2.52e-11 Prostate cancer; TGCT cis rs682748 0.846 rs7704060 chr5:17124559 C/T cg23987134 chr5:17158319 LOC285696 -0.21 -5.14 -0.42 1.03e-6 Hippocampal atrophy; TGCT cis rs4700695 1.000 rs111339 chr5:65420347 T/A cg21114390 chr5:65439923 SFRS12 -0.65 -5.02 -0.41 1.76e-6 Facial morphology (factor 19); TGCT cis rs17030434 0.784 rs6835960 chr4:154650460 G/A cg14289246 chr4:154710475 SFRP2 -0.85 -7.14 -0.54 6.81e-11 Electrocardiographic conduction measures; TGCT cis rs11711311 1.000 rs2566970 chr3:113462123 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.72 7.05 0.54 1.08e-10 IgG glycosylation; TGCT cis rs10479542 0.806 rs4700836 chr5:178976393 A/G cg00080972 chr5:178986291 RUFY1 0.44 5.06 0.41 1.45e-6 Lung cancer; TGCT cis rs2797160 1.000 rs1418642 chr6:125999768 G/A cg05901451 chr6:126070800 HEY2 -0.74 -6.48 -0.5 1.96e-9 Endometrial cancer; TGCT cis rs3749237 0.595 rs17595772 chr3:49409704 G/A cg03060546 chr3:49711283 APEH 0.77 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs254781 0.505 rs190438 chr5:88026902 C/T cg24804195 chr5:87968844 LOC645323 -0.52 -4.64 -0.38 8.62e-6 Intelligence (multi-trait analysis); TGCT cis rs10782582 0.593 rs12126155 chr1:76131555 C/G cg10523679 chr1:76189770 ACADM -0.68 -7.1 -0.54 8.65e-11 Daytime sleep phenotypes; TGCT cis rs3087591 1.000 rs7226006 chr17:29650656 A/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.01 -0.53 1.38e-10 Hip circumference; TGCT cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg06238570 chr21:40685208 BRWD1 -0.69 -6.35 -0.5 3.68e-9 Cognitive function; TGCT cis rs208520 1.000 rs12191598 chr6:66983962 T/C cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs2204008 0.840 rs7136347 chr12:38453531 G/A cg26384229 chr12:38710491 ALG10B 0.88 8.04 0.59 5.98e-13 Bladder cancer; TGCT cis rs644799 1.000 rs586498 chr11:95537828 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg16325326 chr1:53192061 ZYG11B -0.7 -8.66 -0.61 2.13e-14 Monocyte count; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg11003573 chr3:44754125 ZNF502 -0.47 -5.38 -0.43 3.65e-7 Depressive symptoms; TGCT cis rs6693567 0.565 rs698914 chr1:150298750 A/G cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs308403 0.509 rs309379 chr4:123671456 C/G cg10495464 chr4:123653540 BBS12;LOC729338 0.83 12.16 0.74 6.83e-23 Blood protein levels; TGCT cis rs6598955 0.670 rs7531518 chr1:26539749 T/C cg01614726 chr1:26633154 UBXN11 0.49 4.69 0.39 7.09e-6 Obesity-related traits; TGCT cis rs492146 0.783 rs613764 chr6:52840235 C/T cg06706454 chr6:52930286 FBXO9 -0.53 -4.98 -0.41 2.05e-6 Epilepsy (remission after treatment); TGCT cis rs12135062 0.851 rs2651926 chr1:3101820 C/T cg21609526 chr1:3105151 PRDM16 -0.4 -6.52 -0.51 1.58e-9 Migraine; TGCT cis rs12791968 0.765 rs11038250 chr11:45009114 A/G cg11846598 chr11:44996168 LOC221122 -0.31 -5.0 -0.41 1.88e-6 Inhibitory control; TGCT cis rs9916302 0.904 rs11655531 chr17:37697959 T/C cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs9527 0.521 rs12259163 chr10:104961477 A/G cg04362960 chr10:104952993 NT5C2 0.67 5.7 0.46 8.1e-8 Arsenic metabolism; TGCT cis rs6582630 0.576 rs2387837 chr12:38403164 G/T cg26384229 chr12:38710491 ALG10B -0.52 -4.52 -0.38 1.43e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs35146811 0.624 rs1727134 chr7:99813672 T/C cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs7552404 0.731 rs1770885 chr1:76402212 C/T cg03433033 chr1:76189801 ACADM -0.76 -7.81 -0.57 2.07e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7192750 0.586 rs9934812 chr16:71981652 T/G cg06353428 chr16:71660113 MARVELD3 0.75 6.74 0.52 5.43e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg07061783 chr6:25882402 NA -0.47 -4.95 -0.41 2.37e-6 Blood metabolite levels; TGCT cis rs909674 0.690 rs1972280 chr22:39831986 T/A cg05872129 chr22:39784769 NA -0.99 -9.57 -0.65 1.36e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1801251 1.000 rs10933412 chr2:233707226 G/C cg25237894 chr2:233734115 C2orf82 -0.33 -5.94 -0.47 2.71e-8 Coronary artery disease; TGCT cis rs7552404 0.727 rs6678348 chr1:76332463 C/T cg10523679 chr1:76189770 ACADM 0.68 6.27 0.49 5.37e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7611238 0.583 rs9821765 chr3:195148051 T/C cg27323046 chr3:195102265 ACAP2 0.37 4.97 0.41 2.17e-6 Body mass index; TGCT cis rs6867032 1.000 rs4975802 chr5:2019750 T/C cg26168224 chr5:2018326 NA 0.44 7.95 0.58 1.01e-12 Gut microbiome composition (winter); TGCT cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6430585 0.528 rs721765 chr2:136748779 C/A cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs8177253 0.901 rs9843728 chr3:133501407 C/T cg16414030 chr3:133502952 NA -0.62 -9.83 -0.66 3.36e-17 Iron status biomarkers; TGCT cis rs2013441 0.965 rs1544421 chr17:20114217 T/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs6964587 1.000 rs6968870 chr7:91661111 G/C cg17063962 chr7:91808500 NA 0.86 9.25 0.64 8.11e-16 Breast cancer; TGCT cis rs4820539 1.000 rs6003518 chr22:23471533 C/T cg21100191 chr22:23484243 RTDR1 0.89 10.61 0.69 4.23e-19 Bone mineral density; TGCT cis rs6089829 0.962 rs6122344 chr20:61661738 C/T cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs2120019 0.938 rs2289582 chr15:75310394 T/C cg17294928 chr15:75287854 SCAMP5 -0.86 -6.7 -0.52 6.39e-10 Blood trace element (Zn levels); TGCT cis rs1371867 0.875 rs1660320 chr8:101337579 A/C cg06002616 chr8:101225028 SPAG1 -0.54 -6.29 -0.49 4.88e-9 Atrioventricular conduction; TGCT cis rs7226408 0.901 rs1503359 chr18:34742415 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs11190604 1.000 rs2489047 chr10:102347028 A/G cg23241863 chr10:102295624 HIF1AN 0.71 5.36 0.43 3.84e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs933688 1.000 rs985434 chr5:90744509 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 8.8 0.62 9.68e-15 Smoking behavior; TGCT cis rs4851266 1.000 rs13034176 chr2:100833913 G/A cg07810366 chr2:100720526 AFF3 -0.39 -5.73 -0.46 7.19e-8 Educational attainment; TGCT cis rs7582180 0.629 rs6736576 chr2:100950854 C/T cg14675211 chr2:100938903 LONRF2 0.53 5.16 0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs597539 0.690 rs647661 chr11:68625875 T/C cg06028808 chr11:68637592 NA 0.55 6.91 0.53 2.2e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7914558 0.966 rs10786721 chr10:104654383 C/A cg15744005 chr10:104629667 AS3MT -0.41 -5.09 -0.42 1.29e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs56235845 0.694 rs9313758 chr5:176773091 T/G cg16006841 chr5:176797999 RGS14 0.52 7.83 0.58 1.9e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs10984561 0.881 rs10984552 chr9:122247196 A/G cg14242995 chr9:122249943 NA 0.75 6.41 0.5 2.7e-9 Pulmonary function decline; TGCT cis rs112217694 1.000 rs77525704 chr4:104655769 C/T cg24090629 chr4:104641072 TACR3 -1.07 -4.84 -0.4 3.75e-6 Menarche (age at onset); TGCT cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs854765 0.647 rs7212447 chr17:17987067 G/A cg04398451 chr17:18023971 MYO15A -0.37 -6.51 -0.5 1.71e-9 Total body bone mineral density; TGCT cis rs6840360 0.593 rs1366907 chr4:152682749 T/C cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.63e-8 Intelligence (multi-trait analysis); TGCT cis rs3776081 0.600 rs13171150 chr5:149523176 C/T cg18424208 chr5:149546337 CDX1 -0.26 -4.75 -0.39 5.5e-6 Blood protein levels; TGCT cis rs7017914 0.967 rs2639903 chr8:71917444 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.31 -0.43 4.8e-7 Bone mineral density; TGCT cis rs7312933 0.558 rs11181463 chr12:42763636 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.22 0.42 7.3e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4455778 0.727 rs28719863 chr7:49069668 C/G cg26309511 chr7:48887640 NA 0.47 5.33 0.43 4.56e-7 Lung cancer in never smokers; TGCT cis rs2463822 0.764 rs7125402 chr11:62097259 C/T cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs950169 0.723 rs17589320 chr15:84919996 C/A cg17173187 chr15:85201210 NMB 0.54 5.55 0.45 1.67e-7 Schizophrenia; TGCT cis rs360798 0.512 rs2710640 chr2:63144305 A/G cg17519650 chr2:63277830 OTX1 0.59 5.42 0.44 2.99e-7 Coronary artery disease; TGCT cis rs6988636 1.000 rs13260626 chr8:124190317 C/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs1062177 1.000 rs2915880 chr5:151147334 G/A cg00977110 chr5:151150581 G3BP1 0.4 4.62 0.38 9.43e-6 Preschool internalizing problems; TGCT cis rs877282 0.853 rs7083589 chr10:754494 G/A cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs881375 0.933 rs1548784 chr9:123685280 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.12 0.42 1.14e-6 Rheumatoid arthritis; TGCT cis rs727479 0.543 rs6493488 chr15:51513922 G/C cg19946085 chr15:51559439 CYP19A1 -0.31 -4.48 -0.37 1.67e-5 Estradiol levels; TGCT cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.659 rs1159782 chr9:5078117 T/C cg02405213 chr9:5042618 JAK2 -0.75 -9.83 -0.66 3.19e-17 Pediatric autoimmune diseases; TGCT cis rs1555895 0.576 rs7080989 chr10:851455 C/G cg02193355 chr10:851439 NA 0.25 5.6 0.45 1.3e-7 Survival in rectal cancer; TGCT cis rs7264396 0.790 rs12480622 chr20:34234620 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.74 -0.39 5.75e-6 Total cholesterol levels; TGCT cis rs6964587 0.869 rs7812219 chr7:91545727 C/T cg17063962 chr7:91808500 NA -0.84 -8.83 -0.62 8.49e-15 Breast cancer; TGCT cis rs6088580 0.634 rs6058041 chr20:33018008 A/G cg06115741 chr20:33292138 TP53INP2 0.53 4.67 0.39 7.67e-6 Glomerular filtration rate (creatinine); TGCT cis rs2836974 0.897 rs2836924 chr21:40525639 C/T cg11644478 chr21:40555479 PSMG1 1.02 10.86 0.7 1.05e-19 Cognitive function; TGCT cis rs2730245 0.527 rs2730237 chr7:158706166 A/G cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs1635 0.655 rs77986494 chr6:28261497 A/G cg15743358 chr6:28303923 ZNF323 -1.34 -5.96 -0.47 2.44e-8 Schizophrenia; TGCT cis rs2851682 0.706 rs2727270 chr11:61603237 C/T cg19610905 chr11:61596333 FADS2 -0.96 -5.22 -0.42 7.37e-7 Gestational age at birth (child effect);Trans fatty acid levels; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg22520471 chr17:61851767 DDX42;CCDC47 -0.55 -4.98 -0.41 2.11e-6 Prudent dietary pattern; TGCT cis rs7193541 0.691 rs3851728 chr16:74480660 C/T cg01733217 chr16:74700730 RFWD3 0.64 5.91 0.47 3.02e-8 Multiple myeloma; TGCT cis rs7216064 1.000 rs12451511 chr17:65874861 T/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs10193935 0.901 rs222483 chr2:42652184 T/G cg27598129 chr2:42591480 NA -0.38 -5.43 -0.44 2.85e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.808 rs79955955 chr2:43686985 A/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.77 0.39 5.17e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7336332 0.598 rs9581852 chr13:28013748 A/G cg22138327 chr13:27999177 GTF3A 0.79 6.12 0.48 1.15e-8 Weight; TGCT cis rs1215050 0.740 rs804051 chr4:98935935 A/T cg05340658 chr4:99064831 C4orf37 -0.44 -5.35 -0.43 4.13e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3125734 0.607 rs7923556 chr10:64024648 A/G cg05499367 chr10:63213510 TMEM26 -0.33 -4.47 -0.37 1.77e-5 Rheumatoid arthritis; TGCT cis rs523522 0.962 rs10849758 chr12:120971149 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs4654899 0.758 rs6702331 chr1:21516107 A/T cg01072550 chr1:21505969 NA -0.56 -9.32 -0.64 5.53e-16 Superior frontal gyrus grey matter volume; TGCT cis rs6426558 0.502 rs6697665 chr1:227474665 T/C cg10327440 chr1:227177885 CDC42BPA 0.57 6.65 0.51 8.55e-10 Neutrophil percentage of white cells; TGCT cis rs924607 1.000 rs12523022 chr5:598643 C/T cg04476341 chr5:669733 TPPP -0.25 -4.55 -0.38 1.25e-5 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7677751 0.806 rs4864860 chr4:55090021 T/C cg17187183 chr4:55093834 PDGFRA 0.53 6.87 0.52 2.83e-10 Corneal astigmatism; TGCT cis rs2562456 0.917 rs2681376 chr19:21715525 T/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs9649213 0.533 rs62478235 chr7:98030349 G/C cg09267113 chr7:98030324 BAIAP2L1 -0.94 -8.74 -0.62 1.38e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs56309584 0.673 rs56256903 chr17:8123128 T/G cg08322244 chr17:8066669 VAMP2 -0.57 -5.26 -0.43 6.21e-7 Initial pursuit acceleration; TGCT cis rs2749592 0.531 rs1208559 chr10:38221370 T/C cg13531842 chr10:38383804 ZNF37A 0.43 5.07 0.41 1.43e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs17445774 1.000 rs17445774 chr2:200859249 A/G cg23649088 chr2:200775458 C2orf69 -0.49 -7.43 -0.56 1.52e-11 LDL cholesterol to HDL cholesterol ratio; TGCT cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg18305652 chr10:134549665 INPP5A 0.31 5.19 0.42 8.46e-7 Migraine; TGCT cis rs2013441 1.000 rs3850781 chr17:20181939 T/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg14893161 chr1:205819251 PM20D1 0.55 7.75 0.57 2.78e-12 Menarche (age at onset); TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs13256369 0.802 rs12153 chr8:8560909 G/C cg17143192 chr8:8559678 CLDN23 0.54 5.03 0.41 1.64e-6 Obesity-related traits; TGCT cis rs75686122 0.541 rs12681238 chr8:104656185 A/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs922182 0.547 rs12907026 chr15:64271604 A/C cg02919090 chr15:64263738 DAPK2 -0.27 -4.84 -0.4 3.74e-6 Blood protein levels; TGCT cis rs7267979 0.966 rs6050611 chr20:25414419 A/G cg03522245 chr20:25566470 NINL 0.61 6.52 0.51 1.57e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs35934224 0.783 rs7287073 chr22:19864335 G/A cg11182965 chr22:19864308 TXNRD2 -0.38 -5.2 -0.42 7.82e-7 Glaucoma (primary open-angle); TGCT cis rs2067615 0.524 rs10467029 chr12:107078448 C/T cg15890332 chr12:107067104 RFX4 0.29 5.69 0.45 8.83e-8 Heart rate; TGCT cis rs5771242 0.518 rs5771258 chr22:50675648 C/A cg16473166 chr22:50639996 SELO 0.65 5.52 0.44 1.91e-7 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs11190604 1.000 rs2489043 chr10:102334327 T/C cg23241863 chr10:102295624 HIF1AN 0.71 5.39 0.44 3.39e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs16867321 0.950 rs12472841 chr2:181491840 C/A cg23363182 chr2:181467187 NA -0.39 -5.65 -0.45 1.02e-7 Obesity; TGCT cis rs2997447 0.846 rs61775428 chr1:26409126 G/C cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg23758822 chr17:41437982 NA 0.71 6.77 0.52 4.56e-10 Menopause (age at onset); TGCT cis rs7528684 0.872 rs7522061 chr1:157668390 A/G cg17134153 chr1:157670328 FCRL3 -0.25 -4.7 -0.39 6.78e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs8051431 0.915 rs7191900 chr16:72014866 G/A cg06353428 chr16:71660113 MARVELD3 0.58 4.96 0.41 2.28e-6 LDL cholesterol levels; TGCT trans rs1814175 0.817 rs10839401 chr11:49876144 C/T cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs1801251 0.685 rs1515961 chr2:233623763 C/A cg25237894 chr2:233734115 C2orf82 0.26 4.83 0.4 3.9e-6 Coronary artery disease; TGCT cis rs7618915 0.571 rs12487445 chr3:52618319 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.79 -0.4 4.67e-6 Bipolar disorder; TGCT cis rs9807989 0.839 rs10204137 chr2:102968212 A/G cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT trans rs877282 0.898 rs11253346 chr10:765313 A/G cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs3020333 0.875 rs2982570 chr6:152013748 C/T cg22157087 chr6:152012887 ESR1 0.19 4.51 0.38 1.5e-5 Total body bone mineral density; TGCT cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT trans rs28735056 0.596 rs3744879 chr18:77679006 G/C cg05926928 chr17:57297772 GDPD1 -0.69 -6.72 -0.52 5.9e-10 Schizophrenia; TGCT cis rs7714584 1.000 rs2880791 chr5:150267376 C/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg17054783 chr10:134559939 INPP5A 0.26 5.0 0.41 1.94e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7208859 0.614 rs216412 chr17:28903394 A/G cg17105886 chr17:28927953 LRRC37B2 -0.75 -4.56 -0.38 1.23e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs922182 0.617 rs4776264 chr15:64227124 A/G cg02919090 chr15:64263738 DAPK2 0.33 6.16 0.48 9.51e-9 Blood protein levels; TGCT cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg13395646 chr4:1353034 KIAA1530 -0.36 -4.61 -0.38 9.75e-6 Obesity-related traits; TGCT cis rs1865760 0.566 rs10807006 chr6:26048752 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.1e-11 Height; TGCT cis rs769267 0.864 rs7245983 chr19:19657632 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.64 5.25 0.43 6.53e-7 Tonsillectomy; TGCT cis rs6582630 0.502 rs11514371 chr12:38306306 G/C cg26384229 chr12:38710491 ALG10B 0.82 7.18 0.54 5.6e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs6988636 0.710 rs59229243 chr8:124155673 G/A cg23067535 chr8:124195133 FAM83A -0.37 -4.59 -0.38 1.07e-5 Urinary uromodulin levels; TGCT cis rs904251 0.523 rs2797799 chr6:37483620 T/G cg01843034 chr6:37503916 NA -0.54 -7.3 -0.55 3.04e-11 Cognitive performance; TGCT trans rs1814175 0.587 rs7948538 chr11:50021353 A/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs13217239 0.646 rs10946891 chr6:26973215 T/C cg05738196 chr6:26577821 NA 0.49 4.77 0.39 4.98e-6 Schizophrenia; TGCT cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg24549020 chr5:56110836 MAP3K1 -0.67 -5.79 -0.46 5.54e-8 Initial pursuit acceleration; TGCT cis rs3796352 1.000 rs7625448 chr3:53120766 C/A cg15956490 chr3:53032818 SFMBT1 0.53 6.39 0.5 2.97e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs769267 0.930 rs4808965 chr19:19631655 A/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs8135665 0.625 rs8142185 chr22:38451080 A/C cg13116946 chr22:38479732 SLC16A8 0.28 5.54 0.45 1.72e-7 Advanced age-related macular degeneration;Age-related macular degeneration; TGCT cis rs17401966 1.000 rs17410793 chr1:10391886 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.5 -0.37 1.57e-5 Hepatocellular carcinoma; TGCT cis rs62209 0.800 rs17149174 chr10:11002510 A/G cg26901096 chr10:10994189 LOC254312 0.34 5.63 0.45 1.14e-7 Alzheimer's disease (late onset); TGCT cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs2075371 0.863 rs9641966 chr7:133961205 G/A cg11752832 chr7:134001865 SLC35B4 0.66 5.5 0.44 2.09e-7 Mean platelet volume; TGCT cis rs13082711 0.522 rs646577 chr3:27352225 A/G cg02860705 chr3:27208620 NA 0.33 5.37 0.43 3.67e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs6545883 0.859 rs13004855 chr2:61505072 C/T cg15711740 chr2:61764176 XPO1 0.56 4.78 0.39 4.81e-6 Tuberculosis; TGCT cis rs7120118 0.517 rs17726390 chr11:47319706 C/T cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.26e-7 HDL cholesterol; TGCT cis rs12681366 0.762 rs3019148 chr8:95429635 T/C cg27091703 chr8:95487428 RAD54B -0.54 -4.52 -0.38 1.4e-5 Nonsyndromic cleft lip with cleft palate; TGCT cis rs1799949 0.965 rs799917 chr17:41244936 G/A cg10047753 chr17:41438598 NA 0.74 7.0 0.53 1.46e-10 Menopause (age at onset); TGCT cis rs875971 0.660 rs801193 chr7:66030612 A/C cg18876405 chr7:65276391 NA -0.37 -5.6 -0.45 1.33e-7 Aortic root size; TGCT cis rs9473924 0.505 rs2817416 chr6:50809777 T/C cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs7772486 0.846 rs2144478 chr6:146381445 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.59 0.65 1.22e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs909341 0.909 rs6122159 chr20:62370732 G/T cg14758556 chr20:62440591 NA 0.31 4.61 0.38 9.85e-6 Atopic dermatitis; TGCT cis rs10769945 0.500 rs217203 chr11:1972456 G/C cg18032502 chr11:1949113 TNNT3 -0.25 -4.82 -0.4 4.06e-6 DNA methylation (variation); TGCT cis rs1048238 0.935 rs761760 chr1:16342419 A/G cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Systolic blood pressure; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg25767906 chr1:53392781 SCP2 0.53 6.23 0.49 6.49e-9 Monocyte count; TGCT cis rs950169 0.580 rs2271431 chr15:85189464 A/C cg11189052 chr15:85197271 WDR73 0.77 6.47 0.5 2.05e-9 Schizophrenia; TGCT cis rs1799949 1.000 rs16940 chr17:41245237 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.01 0.41 1.81e-6 Menopause (age at onset); TGCT cis rs826838 1.000 rs826838 chr12:39106731 C/T cg26384229 chr12:38710491 ALG10B -0.8 -7.35 -0.55 2.29e-11 Heart rate; TGCT cis rs12134245 0.747 rs35654098 chr1:92001452 T/A cg02896835 chr1:92012615 NA -0.27 -4.59 -0.38 1.08e-5 Breast cancer; TGCT cis rs2153535 0.580 rs1335643 chr6:8488021 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2204008 0.580 rs11520047 chr12:38051778 T/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs200810 0.694 rs55839714 chr6:98019876 C/T cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.64 -4.45 -0.37 1.91e-5 Body mass index; TGCT cis rs2456568 0.571 rs1105114 chr11:93693511 C/T cg17595323 chr11:93583763 C11orf90 0.38 4.62 0.38 9.46e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7412746 0.611 rs2271076 chr1:150916657 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT trans rs9650657 0.513 rs4314618 chr8:10816772 A/G cg06636001 chr8:8085503 FLJ10661 -0.85 -8.39 -0.6 9.04e-14 Neuroticism; TGCT cis rs1205863 1.000 rs209815 chr6:11951314 C/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs9318086 0.904 rs9580769 chr13:24439724 T/C cg25267304 chr13:24462978 PCOTH;MIPEP -0.68 -6.81 -0.52 3.69e-10 Myopia (pathological); TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.1 -15.96 -0.82 7.48e-32 Prudent dietary pattern; TGCT cis rs2032447 0.899 rs1090947 chr6:26076642 T/C cg03264133 chr6:25882463 NA -0.67 -6.04 -0.48 1.67e-8 Intelligence (multi-trait analysis); TGCT cis rs11249608 0.590 rs36051170 chr5:178447971 T/C cg21905437 chr5:178450457 ZNF879 0.44 4.45 0.37 1.92e-5 Pubertal anthropometrics; TGCT cis rs1420338 0.933 rs12540602 chr7:34174056 G/A cg01275685 chr7:34179230 BMPER -0.28 -5.05 -0.41 1.53e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs11148252 0.774 rs6561666 chr13:52930045 A/G cg02158880 chr13:53174818 NA 0.39 4.69 0.39 6.96e-6 Lewy body disease; TGCT cis rs13242816 1.000 rs66985071 chr7:116130433 C/T cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs977747 0.815 rs6692253 chr1:47680527 G/A cg03885399 chr1:47691550 TAL1 -0.42 -5.48 -0.44 2.32e-7 Body mass index; TGCT cis rs6754311 0.773 rs309179 chr2:136613780 G/A cg07169764 chr2:136633963 MCM6 -0.62 -5.74 -0.46 7e-8 Mosquito bite size; TGCT cis rs17376456 0.877 rs28418572 chr5:93144161 A/C cg25358565 chr5:93447407 FAM172A 0.89 7.62 0.56 5.67e-12 Diabetic retinopathy; TGCT cis rs2204008 0.539 rs1283295 chr12:38146014 A/C cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs7949030 0.596 rs71490394 chr11:62370155 G/A cg22862634 chr11:62369728 EML3;MTA2 0.7 8.89 0.62 5.98e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.512 rs132784 chr22:42052363 G/A cg17554472 chr22:41940697 POLR3H 0.52 5.37 0.43 3.68e-7 Vitiligo; TGCT cis rs4970988 0.787 rs1532770 chr1:150725335 G/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.67 0.39 7.73e-6 Urate levels; TGCT cis rs931608 1.000 rs11085534 chr19:22613229 A/G cg23859931 chr19:22123797 NA 0.53 4.49 0.37 1.61e-5 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs2404602 0.716 rs67888330 chr15:76752483 A/G cg26408565 chr15:76604113 ETFA -0.4 -5.26 -0.43 6.23e-7 Blood metabolite levels; TGCT cis rs4566357 0.557 rs2272201 chr2:227912551 T/A cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.9e-7 Coronary artery disease; TGCT cis rs8180040 0.871 rs11716661 chr3:47517773 G/T cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs11096990 0.593 rs35552004 chr4:39172534 C/T cg24403649 chr4:39172243 NA 0.2 4.48 0.37 1.7e-5 Cognitive function; TGCT cis rs7119 0.679 rs12914932 chr15:77839051 G/A cg27398640 chr15:77910606 LINGO1 -0.27 -5.1 -0.42 1.22e-6 Type 2 diabetes; TGCT cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs12477438 0.520 rs4851188 chr2:99745898 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs3091242 0.935 rs3093632 chr1:25684012 C/T cg23205692 chr1:25664452 TMEM50A 0.53 5.47 0.44 2.33e-7 Erythrocyte sedimentation rate; TGCT cis rs7296418 0.630 rs28419092 chr12:123812629 G/C cg00376283 chr12:123451042 ABCB9 0.62 5.29 0.43 5.46e-7 Platelet count; TGCT cis rs986417 0.636 rs8020587 chr14:60952612 A/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs13108904 0.517 rs4974551 chr4:1336410 C/A cg00684032 chr4:1343700 KIAA1530 0.22 4.73 0.39 5.89e-6 Obesity-related traits; TGCT cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg10117171 chr1:25599238 RHD 0.3 4.79 0.4 4.67e-6 Erythrocyte sedimentation rate; TGCT cis rs2243480 0.522 rs778717 chr7:65848151 G/C cg18252515 chr7:66147081 NA -1.08 -6.17 -0.48 9.09e-9 Diabetic kidney disease; TGCT cis rs7613051 0.945 rs13080709 chr3:33053282 C/T cg19000631 chr3:33138515 GLB1;TMPPE 0.67 4.9 0.4 2.92e-6 Atopic dermatitis; TGCT cis rs7975161 0.572 rs7957725 chr12:104574749 A/T cg25273343 chr12:104657179 TXNRD1 -0.33 -4.92 -0.4 2.68e-6 Toenail selenium levels; TGCT cis rs79149102 0.579 rs8040961 chr15:75291864 G/A cg09165964 chr15:75287851 SCAMP5 -1.06 -5.82 -0.46 4.83e-8 Lung cancer; TGCT cis rs9926296 0.687 rs258317 chr16:89732238 C/T cg26513180 chr16:89883248 FANCA -0.67 -6.31 -0.49 4.58e-9 Vitiligo; TGCT cis rs9303401 0.614 rs62084387 chr17:57148027 C/T cg25039879 chr17:56429692 SUPT4H1 0.54 4.8 0.4 4.49e-6 Cognitive test performance; TGCT cis rs228769 0.543 rs170634 chr17:42175821 C/A cg13607699 chr17:42295918 UBTF -0.63 -5.26 -0.43 6.1e-7 Bone mineral density (hip);Bone mineral density (spine); TGCT cis rs67311347 1.000 rs6599102 chr3:40468406 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs769267 0.859 rs2916076 chr19:19545990 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.25 0.43 6.3e-7 Tonsillectomy; TGCT cis rs1395 0.744 rs11686131 chr2:27508710 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 8.02 0.58 6.76e-13 Blood metabolite levels; TGCT cis rs736408 0.540 rs4687637 chr3:52634092 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs500492 0.542 rs449295 chr16:1074443 G/A cg01366354 chr16:1075121 NA 0.36 5.23 0.43 6.99e-7 Polycystic ovary syndrome; TGCT cis rs12497850 0.931 rs9846123 chr3:49088112 C/T cg07636037 chr3:49044803 WDR6 -0.96 -10.9 -0.7 8.39e-20 Parkinson's disease; TGCT cis rs61776719 0.738 rs7555461 chr1:38444749 T/C cg26398791 chr1:38455867 SF3A3 0.6 5.87 0.47 3.73e-8 Coronary artery disease; TGCT cis rs7246657 0.722 rs2972458 chr19:38135403 T/C cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg12042659 chr19:58951599 ZNF132 0.52 4.59 0.38 1.07e-5 Uric acid clearance; TGCT cis rs4665809 0.590 rs2384361 chr2:26452209 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.99 -7.31 -0.55 2.9100000000000002e-11 Gut microbiome composition (summer); TGCT cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1903068 0.597 rs10013070 chr4:55997201 A/G cg01777861 chr4:56023843 NA 0.53 5.81 0.46 4.92e-8 Endometriosis; TGCT cis rs10504229 1.000 rs67039591 chr8:58174553 T/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs425277 0.500 rs908744 chr1:2038893 G/A cg24578937 chr1:2090814 PRKCZ -0.23 -5.36 -0.43 3.88e-7 Height; TGCT cis rs4252435 0.614 rs6961869 chr7:142597508 C/T cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs6748734 1.000 rs6724662 chr2:241831560 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -6.32 -0.49 4.22e-9 Urinary metabolites; TGCT cis rs7727544 0.716 rs7701414 chr5:131585958 A/G cg22598563 chr5:131563921 P4HA2 -0.28 -4.55 -0.38 1.27e-5 Blood metabolite levels; TGCT cis rs2073300 1.000 rs6036423 chr20:23459810 A/C cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7772486 0.641 rs960385 chr6:146371074 G/A cg05347473 chr6:146136440 FBXO30 0.57 5.38 0.44 3.56e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9972944 0.756 rs2873818 chr17:63762867 A/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.24 -0.43 6.6e-7 Total body bone mineral density; TGCT cis rs910316 0.935 rs3742771 chr14:75599647 A/G cg11812906 chr14:75593930 NEK9 0.73 7.18 0.54 5.79e-11 Height; TGCT cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg13695892 chr22:41940480 POLR3H 0.9 8.73 0.62 1.46e-14 Vitiligo; TGCT cis rs12615966 0.932 rs17020857 chr2:105401306 A/G cg16465502 chr2:105461796 NA -0.78 -5.01 -0.41 1.83e-6 Pancreatic cancer; TGCT cis rs1532993 0.518 rs6847710 chr4:98615493 A/G cg05340658 chr4:99064831 C4orf37 -0.37 -4.44 -0.37 1.98e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6450176 0.951 rs5013866 chr5:53300947 A/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs9527 0.571 rs12219246 chr10:104613355 A/G cg04362960 chr10:104952993 NT5C2 0.55 4.73 0.39 5.91e-6 Arsenic metabolism; TGCT cis rs3733585 0.605 rs4697710 chr4:10122649 T/C cg00071950 chr4:10020882 SLC2A9 -0.51 -5.29 -0.43 5.33e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4389656 0.826 rs192443 chr5:6733664 G/T cg10857441 chr5:6722123 POLS -0.22 -4.78 -0.39 4.8e-6 Coronary artery disease; TGCT cis rs1555895 0.576 rs748112 chr10:862889 C/T cg02193355 chr10:851439 NA 0.2 4.64 0.38 8.55e-6 Survival in rectal cancer; TGCT cis rs9910055 0.529 rs228765 chr17:42186422 C/T cg13607699 chr17:42295918 UBTF -0.62 -4.97 -0.41 2.18e-6 Total body bone mineral density; TGCT cis rs907683 0.583 rs10932803 chr2:220292739 A/T cg15015639 chr2:220282977 DES 0.4 5.11 0.42 1.18e-6 Resting heart rate; TGCT cis rs6733011 0.530 rs7608889 chr2:99481350 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -4.55 -0.38 1.24e-5 Bipolar disorder; TGCT cis rs9467711 1.000 rs6939799 chr6:26328366 G/A cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2239547 0.522 rs2581801 chr3:52972907 G/T cg11645453 chr3:52864694 ITIH4 -0.32 -5.3 -0.43 5.13e-7 Schizophrenia; TGCT cis rs6728302 0.557 rs2741321 chr2:233280239 A/G cg06555452 chr2:233241558 NA -0.33 -5.0 -0.41 1.9e-6 Height; TGCT cis rs826838 0.967 rs10875979 chr12:39095149 G/A cg26384229 chr12:38710491 ALG10B 0.98 9.38 0.64 3.92e-16 Heart rate; TGCT cis rs793571 0.544 rs383902 chr15:59034174 C/T cg05156742 chr15:59063176 FAM63B 0.5 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs6570726 0.935 rs409725 chr6:145840340 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3824867 0.920 rs10742805 chr11:47454701 A/G cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs2721195 0.816 rs4251689 chr8:145741130 C/T cg11211951 chr8:145729740 GPT 0.27 6.58 0.51 1.17e-9 Age at first birth; TGCT cis rs7666738 0.830 rs6834014 chr4:98951431 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2832191 0.626 rs2254796 chr21:30341891 A/G cg08807101 chr21:30365312 RNF160 -0.63 -6.01 -0.48 1.9e-8 Dental caries; TGCT cis rs7267979 1.000 rs6050561 chr20:25334855 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7511006 0.859 rs7292228 chr22:50649560 C/G cg19026356 chr22:50624276 TRABD -0.49 -4.57 -0.38 1.17e-5 Obesity-related traits; TGCT cis rs8177253 0.965 rs1525889 chr3:133490033 A/C cg20276088 chr3:133502917 NA -0.24 -5.13 -0.42 1.06e-6 Iron status biomarkers; TGCT cis rs9818758 0.607 rs11716445 chr3:49406095 C/T cg08550065 chr3:50336684 HYAL3;NAT6 1.18 4.89 0.4 3.03e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7572733 0.534 rs7572123 chr2:198769637 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.11 0.42 1.21e-6 Dermatomyositis; TGCT trans rs3780486 0.505 rs10758194 chr9:33157419 G/T cg04842962 chr6:43655489 MRPS18A 0.8 8.67 0.61 2.02e-14 IgG glycosylation; TGCT cis rs72843506 0.722 rs12051550 chr17:20129546 A/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.89 -0.4 3.07e-6 Schizophrenia; TGCT cis rs10883723 0.962 rs1056741 chr10:104236640 A/C cg05855489 chr10:104503620 C10orf26 -0.55 -4.68 -0.39 7.42e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12142240 0.660 rs6679080 chr1:46819779 A/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs3749237 0.595 rs17650792 chr3:49390250 A/G cg07636037 chr3:49044803 WDR6 0.64 6.03 0.48 1.72e-8 Resting heart rate; TGCT cis rs3213545 0.676 rs1179998 chr12:121483653 G/A cg02403541 chr12:121454288 C12orf43 0.66 6.05 0.48 1.6e-8 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs7666738 0.830 rs36047842 chr4:99004902 C/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9291683 0.595 rs3733585 chr4:10036339 A/G cg00071950 chr4:10020882 SLC2A9 0.68 8.84 0.62 7.71e-15 Bone mineral density; TGCT cis rs9527 1.000 rs12416687 chr10:104629011 T/C cg04362960 chr10:104952993 NT5C2 0.66 5.42 0.44 3.04e-7 Arsenic metabolism; TGCT cis rs7829975 0.501 rs4840353 chr8:8580570 A/G cg06636001 chr8:8085503 FLJ10661 -0.55 -4.62 -0.38 9.47e-6 Mood instability; TGCT cis rs1799949 0.550 rs2343818 chr17:41409774 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs10089 1.000 rs883074 chr5:127445823 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.77 -5.99 -0.47 2.07e-8 Ileal carcinoids; TGCT cis rs7020830 0.522 rs10814509 chr9:37111057 A/G cg14294708 chr9:37120828 ZCCHC7 0.81 8.61 0.61 2.73e-14 Schizophrenia; TGCT cis rs12681288 0.963 rs7822955 chr8:1029090 C/T cg04851639 chr8:1020857 NA 0.39 6.82 0.52 3.55e-10 Schizophrenia; TGCT cis rs6430585 0.528 rs895285 chr2:136710554 A/G cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs7819412 0.502 rs4841499 chr8:10988138 A/C cg21775007 chr8:11205619 TDH -0.53 -4.86 -0.4 3.4e-6 Triglycerides; TGCT cis rs7085104 0.513 rs192569 chr10:104577915 T/C cg04362960 chr10:104952993 NT5C2 -0.5 -4.46 -0.37 1.79e-5 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs11247915 0.600 rs11247917 chr1:26655507 G/T cg01414934 chr1:26605969 SH3BGRL3 0.22 4.65 0.39 8.26e-6 Obesity-related traits; TGCT cis rs2456568 0.543 rs4144616 chr11:93621900 A/G cg26875233 chr11:93583750 C11orf90 -0.47 -6.03 -0.48 1.71e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs17253792 0.822 rs76264681 chr14:56060447 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3617 0.625 rs7620690 chr3:52891707 A/G cg11645453 chr3:52864694 ITIH4 -0.29 -5.68 -0.45 9.09e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7727544 0.904 rs58835386 chr5:131600559 A/G cg24060327 chr5:131705240 SLC22A5 -0.6 -6.4 -0.5 2.92e-9 Blood metabolite levels; TGCT cis rs3125734 0.633 rs7100297 chr10:63985100 T/C cg19640130 chr10:64028056 RTKN2 -0.39 -5.11 -0.42 1.19e-6 Rheumatoid arthritis; TGCT cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs1801251 0.727 rs13029336 chr2:233569935 A/G cg08000102 chr2:233561755 GIGYF2 -0.59 -6.66 -0.51 7.81e-10 Coronary artery disease; TGCT cis rs8177179 0.967 rs4994582 chr3:133437566 G/C cg16262614 chr3:133464971 TF 0.34 4.52 0.38 1.44e-5 Iron status biomarkers (transferrin levels); TGCT cis rs10744422 0.925 rs897391 chr12:123326374 G/A cg25930673 chr12:123319894 HIP1R -0.85 -5.01 -0.41 1.86e-6 Schizophrenia; TGCT cis rs9325144 0.581 rs2653758 chr12:38946233 G/T cg13010199 chr12:38710504 ALG10B -0.51 -4.83 -0.4 4.03e-6 Morning vs. evening chronotype; TGCT cis rs4901869 1.000 rs4901869 chr14:59334128 A/G cg02291164 chr14:59296302 NA 0.24 4.77 0.39 5.17e-6 Panic disorder; TGCT cis rs35146811 0.555 rs2525539 chr7:99545309 A/G cg13334819 chr7:99746414 C7orf59 0.6 5.09 0.42 1.28e-6 Coronary artery disease; TGCT cis rs7523273 0.606 rs1830764 chr1:207917052 G/A cg22525895 chr1:207977042 MIR29B2 0.54 8.77 0.62 1.16e-14 Schizophrenia; TGCT cis rs9972944 0.729 rs62065062 chr17:63777383 G/A cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs2239547 0.522 rs9865094 chr3:52985319 G/C cg11645453 chr3:52864694 ITIH4 -0.32 -5.28 -0.43 5.48e-7 Schizophrenia; TGCT cis rs2742417 0.565 rs2673031 chr3:45756986 A/G cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6450176 0.680 rs255756 chr5:53309364 A/G ch.5.1024479R chr5:53302184 ARL15 -0.83 -6.14 -0.48 1.04e-8 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2439831 1.000 rs537115 chr15:43729948 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs9902453 0.845 rs2628165 chr17:28121166 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 7.04 0.53 1.17e-10 Coffee consumption (cups per day); TGCT cis rs983545 0.607 rs9846524 chr3:16922923 C/G cg21767191 chr3:17082105 PLCL2 0.22 4.5 0.37 1.52e-5 Blood protein levels; TGCT cis rs2742417 1.000 rs2742368 chr3:45752293 C/A cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6723226 0.765 rs12612824 chr2:32579759 C/T cg02381751 chr2:32503542 YIPF4 -0.6 -5.54 -0.45 1.75e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.831 rs34592564 chr21:40516288 G/C cg11890956 chr21:40555474 PSMG1 1.03 10.49 0.69 7.98e-19 Cognitive function; TGCT cis rs208520 0.661 rs207090 chr6:66783963 T/A cg07460842 chr6:66804631 NA -0.94 -9.84 -0.66 3.12e-17 Exhaled nitric oxide output; TGCT cis rs1153858 1.000 rs1820518 chr15:45694579 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7524258 0.868 rs4908451 chr1:7299618 C/G cg07173049 chr1:7289937 CAMTA1 -0.29 -4.93 -0.4 2.62e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs11658309 1 rs11658309 chr17:17762247 T/G cg04398451 chr17:18023971 MYO15A 0.28 4.51 0.38 1.49e-5 Strep throat; TGCT cis rs12579753 1.000 rs10862373 chr12:82250657 A/G cg07988820 chr12:82153109 PPFIA2 -0.6 -6.61 -0.51 1.02e-9 Resting heart rate; TGCT cis rs6679073 1.000 rs6679073 chr1:205756484 A/C cg23034840 chr1:205782522 SLC41A1 0.7 6.09 0.48 1.28e-8 Prostate-specific antigen levels; TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs4786125 0.920 rs7194057 chr16:6895960 T/C cg03623568 chr16:6915990 A2BP1 -0.38 -5.14 -0.42 1.02e-6 Heart rate variability traits (SDNN); TGCT cis rs597539 0.652 rs611046 chr11:68631704 A/G cg21963583 chr11:68658836 MRPL21 0.36 6.07 0.48 1.43e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs763121 0.819 rs6001205 chr22:39100264 T/A cg06022373 chr22:39101656 GTPBP1 0.74 7.31 0.55 2.94e-11 Menopause (age at onset); TGCT cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs7804356 1.000 rs1327988 chr7:26828965 C/G cg03456212 chr7:26904342 SKAP2 0.62 4.71 0.39 6.65e-6 Type 1 diabetes; TGCT cis rs4824093 0.610 rs9627799 chr22:50317989 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.15 -4.45 -0.37 1.86e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6060960 0.537 rs6089119 chr20:30514161 T/G cg06102403 chr20:30458708 TTLL9;DUSP15 0.4 4.57 0.38 1.16e-5 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT trans rs75565482 0.546 rs12090359 chr1:168458546 G/A cg24696473 chr17:17683032 SMCR5;RAI1 0.48 6.73 0.52 5.5e-10 Emphysema imaging phenotypes; TGCT cis rs4919694 0.572 rs12261294 chr10:104934952 C/T cg04362960 chr10:104952993 NT5C2 0.97 6.81 0.52 3.82e-10 Arsenic metabolism; TGCT cis rs1580019 0.587 rs7806941 chr7:32553319 G/T cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.98 0.41 2.05e-6 Cognitive ability; TGCT cis rs13088645 0.621 rs7611834 chr3:134146088 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.54 5.02 0.41 1.78e-6 Coronary artery disease; TGCT cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg03806693 chr22:41940476 POLR3H -1.14 -13.41 -0.77 6.99e-26 Vitiligo; TGCT cis rs12188164 0.930 rs72717440 chr5:449701 A/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs3820068 0.608 rs7519899 chr1:16045579 A/G cg05660106 chr1:15850417 CASP9 0.73 6.75 0.52 5.18e-10 Systolic blood pressure; TGCT cis rs2013441 1.000 rs2158473 chr17:20139090 T/C cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs78487399 0.614 rs13422551 chr2:43724682 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.82 -0.4 4.03e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6089584 0.927 rs1886007 chr20:60581049 G/A cg16423285 chr20:60520624 NA -0.62 -6.89 -0.53 2.48e-10 Body mass index; TGCT cis rs17221829 0.733 rs10830327 chr11:89389122 G/A cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg10819733 chr22:24237672 NA -0.33 -5.44 -0.44 2.7e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10893109 0.967 rs2045071 chr11:123797007 G/A cg14126608 chr11:122846540 NA -0.28 -4.45 -0.37 1.87e-5 Facial morphology (factor 13, vertical position of alar curvature relative to upper lip); TGCT cis rs10464366 1.000 rs10464366 chr7:39121500 A/T cg08835956 chr7:39171034 POU6F2 -0.23 -4.59 -0.38 1.08e-5 IgG glycosylation; TGCT cis rs2180341 1.000 rs6569483 chr6:127658855 G/A cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs7513165 0.660 rs12040249 chr1:204158228 C/T cg24450653 chr1:205060293 RBBP5 0.21 4.5 0.37 1.57e-5 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs8031584 0.678 rs798086 chr15:31129211 C/G cg08109568 chr15:31115862 NA 0.4 5.24 0.43 6.73e-7 Huntington's disease progression; TGCT cis rs910316 0.967 rs7146523 chr14:75659880 T/C cg11812906 chr14:75593930 NEK9 -0.72 -6.87 -0.53 2.72e-10 Height; TGCT cis rs2046867 0.908 rs1106310 chr3:72818902 A/T cg25664220 chr3:72788482 NA 0.56 7.18 0.54 5.54e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6582630 0.502 rs2387603 chr12:38353389 A/C cg26384229 chr12:38710491 ALG10B 0.78 6.94 0.53 1.91e-10 Drug-induced liver injury (flucloxacillin); TGCT trans rs10506458 0.834 rs73125186 chr12:63373400 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.46 -7.24 -0.55 4.04e-11 Hemostatic factors and hematological phenotypes; TGCT cis rs798766 1.000 rs798754 chr4:1720757 A/G cg05874882 chr4:1763078 NA -0.37 -4.93 -0.4 2.6e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs6460942 0.643 rs7780093 chr7:12233661 C/G cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs9549367 0.789 rs3861720 chr13:113906097 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs4728071 0.568 rs10232298 chr7:127219417 A/G cg22282131 chr7:127439670 SND1 0.21 4.46 0.37 1.82e-5 Intelligence (multi-trait analysis); TGCT cis rs854765 0.663 rs4925120 chr17:17754633 C/T cg09796270 chr17:17721594 SREBF1 -0.26 -4.93 -0.4 2.59e-6 Total body bone mineral density; TGCT cis rs7666738 0.716 rs6827474 chr4:99089683 T/G cg18180107 chr4:99064573 C4orf37 0.55 4.94 0.41 2.45e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6912958 0.712 rs9444526 chr6:88326402 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT trans rs9991510 0.586 rs2903246 chr4:12141834 A/T cg04834502 chr16:48644360 N4BP1 -0.95 -6.86 -0.52 2.85e-10 Photic sneeze reflex; TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT trans rs1814175 0.817 rs10769641 chr11:49960141 A/G cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs6690583 0.573 rs7547317 chr1:85456961 T/G cg20280350 chr1:85513789 MCOLN3 -0.79 -5.27 -0.43 5.77e-7 Serum sulfate level; TGCT cis rs2455799 0.593 rs2470544 chr3:15727234 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.65e-6 Mean platelet volume; TGCT trans rs208520 0.837 rs208471 chr6:66916749 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -9.95 -0.67 1.64e-17 Exhaled nitric oxide output; TGCT cis rs17345786 0.906 rs11710016 chr3:101120030 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.84 -8.92 -0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs524281 0.817 rs10896097 chr11:65967953 A/C cg00563793 chr11:65837595 PACS1 0.54 4.71 0.39 6.4e-6 Electroencephalogram traits; TGCT cis rs9811216 0.958 rs9827710 chr3:169522387 G/C cg08193579 chr3:169529701 LRRC34 0.3 4.59 0.38 1.05e-5 Neutrophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs2228479 0.681 rs10153196 chr16:89967397 A/C cg06558623 chr16:89946397 TCF25 0.41 4.99 0.41 1.97e-6 Skin colour saturation; TGCT cis rs4455778 0.580 rs7780178 chr7:49085140 A/G cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs13188771 0.614 rs66592082 chr5:100914515 T/C cg10455971 chr5:101119566 NA 0.45 4.64 0.38 8.85e-6 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs3020736 0.500 rs1801311 chr22:42486723 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.875 rs6909827 chr6:146365738 A/G cg23711669 chr6:146136114 FBXO30 0.85 9.44 0.65 2.92e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg24675658 chr1:53192096 ZYG11B 0.74 8.69 0.62 1.75e-14 Monocyte count; TGCT cis rs12472274 0.941 rs2880131 chr2:239089151 A/C cg17459225 chr2:239074497 NA 0.34 5.02 0.41 1.78e-6 Phospholipid levels (plasma); TGCT cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.41 -4.88 -0.4 3.13e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs854765 0.856 rs2955382 chr17:17947710 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.67 -6.46 -0.5 2.13e-9 Total body bone mineral density; TGCT cis rs9634489 0.502 rs732103 chr13:97099614 A/G cg11411106 chr13:97107445 HS6ST3 -0.25 -4.46 -0.37 1.82e-5 Body mass index; TGCT cis rs7474896 0.515 rs675628 chr10:38305331 C/G cg13720705 chr10:37990370 NA -0.37 -4.68 -0.39 7.35e-6 Obesity (extreme); TGCT cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.56 4.81 0.4 4.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3821902 0.691 rs73120936 chr3:64050945 T/C cg22134162 chr3:63841271 THOC7 -0.34 -4.97 -0.41 2.19e-6 Breast cancer; TGCT cis rs6964587 0.869 rs405 chr7:91546327 G/C cg17063962 chr7:91808500 NA -0.86 -9.19 -0.64 1.16e-15 Breast cancer; TGCT cis rs9858542 1.000 rs11709525 chr3:49690496 C/T cg03060546 chr3:49711283 APEH -0.67 -6.0 -0.47 2.06e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2963155 0.518 rs853184 chr5:142640901 C/T cg17617527 chr5:142782415 NR3C1 0.85 6.34 0.49 3.85e-9 Breast cancer; TGCT cis rs7296418 0.816 rs1790096 chr12:123710364 C/T cg00376283 chr12:123451042 ABCB9 0.84 7.67 0.57 4.4e-12 Platelet count; TGCT cis rs4517514 0.509 rs10830417 chr11:89871940 A/G cg14505434 chr11:89522851 NA 0.45 4.45 0.37 1.87e-5 Trans fatty acid levels; TGCT cis rs79387448 0.745 rs17027413 chr2:103153667 A/G cg09003973 chr2:102972529 NA -0.96 -5.92 -0.47 2.95e-8 Gut microbiota (bacterial taxa); TGCT cis rs4654899 0.965 rs7512116 chr1:21501095 C/A cg01072550 chr1:21505969 NA -0.5 -8.08 -0.59 4.94e-13 Superior frontal gyrus grey matter volume; TGCT cis rs1568889 0.838 rs10835276 chr11:28167147 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.03 0.7 4.03e-20 Bipolar disorder; TGCT cis rs9818758 0.505 rs67286839 chr3:49265744 C/T cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9296092 0.538 rs9469488 chr6:33517117 G/T cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.25e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9486715 0.867 rs4839842 chr6:96955387 A/T cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs6964587 0.967 rs6970743 chr7:91744311 C/G cg22709100 chr7:91322751 NA 0.29 4.75 0.39 5.61e-6 Breast cancer; TGCT trans rs1814175 0.647 rs61306292 chr11:49856040 G/C cg15704280 chr7:45808275 SEPT13 -0.71 -7.92 -0.58 1.18e-12 Height; TGCT cis rs6964587 1.000 rs10280927 chr7:91582205 G/A cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs35146811 0.735 rs2272345 chr7:99797031 C/G cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs13242816 1.000 rs56010123 chr7:116173046 C/T cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs2153535 0.580 rs9405391 chr6:8466548 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs899997 1.000 rs11634628 chr15:79005579 G/A cg00061860 chr15:78953028 NA -0.25 -4.61 -0.38 9.69e-6 Coronary artery disease or large artery stroke; TGCT cis rs910316 1.000 rs11159117 chr14:75584867 C/T cg23033748 chr14:75592666 NEK9 0.27 4.61 0.38 9.79e-6 Height; TGCT cis rs1903068 0.853 rs9312655 chr4:56002665 T/C cg16572876 chr4:56024045 NA 0.42 4.79 0.39 4.75e-6 Endometriosis; TGCT cis rs10744422 1.000 rs4759355 chr12:123316566 A/G cg25930673 chr12:123319894 HIP1R -0.85 -5.01 -0.41 1.86e-6 Schizophrenia; TGCT cis rs7020830 0.571 rs7031314 chr9:37376122 A/T cg14294708 chr9:37120828 ZCCHC7 -0.94 -9.45 -0.65 2.78e-16 Schizophrenia; TGCT cis rs13242816 1.000 rs62471198 chr7:116107963 T/C cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT cis rs4478858 0.684 rs10798837 chr1:31719340 C/T cg07478791 chr1:31886160 SERINC2 -0.49 -4.8 -0.4 4.51e-6 Alcohol dependence; TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg24503407 chr1:205819492 PM20D1 0.57 7.93 0.58 1.08e-12 Menarche (age at onset); TGCT cis rs1008375 0.900 rs6812675 chr4:17597549 A/G cg16339924 chr4:17578868 LAP3 0.84 6.77 0.52 4.62e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs36051895 0.589 rs6476945 chr9:5191793 C/T cg02405213 chr9:5042618 JAK2 -0.7 -9.3 -0.64 6.3e-16 Pediatric autoimmune diseases; TGCT cis rs2180341 0.842 rs9375492 chr6:127545492 C/T cg27446573 chr6:127587934 RNF146 -1.06 -8.46 -0.6 6.28e-14 Breast cancer; TGCT cis rs4517514 0.509 rs10830411 chr11:89865532 A/G cg14505434 chr11:89522851 NA 0.45 4.46 0.37 1.82e-5 Trans fatty acid levels; TGCT cis rs17767294 0.708 rs116146221 chr6:27853392 G/A cg08851530 chr6:28072375 NA 1.58 6.37 0.5 3.43e-9 Parkinson's disease; TGCT cis rs28374715 0.532 rs3204853 chr15:41689166 C/A cg18705301 chr15:41695430 NDUFAF1 -0.94 -16.47 -0.83 5.12e-33 Ulcerative colitis; TGCT cis rs7829975 0.667 rs1877119 chr8:8707197 C/G cg06636001 chr8:8085503 FLJ10661 0.7 6.21 0.49 7.39e-9 Mood instability; TGCT cis rs3096299 0.719 rs2353581 chr16:89518908 T/C cg02187348 chr16:89574699 SPG7 0.6 6.39 0.5 2.98e-9 Multiple myeloma (IgH translocation); TGCT cis rs8100891 0.734 rs8104048 chr19:32829306 A/G cg16662424 chr19:32837316 ZNF507 -0.46 -5.54 -0.45 1.76e-7 Neuroticism; TGCT cis rs11190604 1.000 rs12358187 chr10:102284449 C/G cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.962 rs11728816 chr4:98951767 C/T cg18180107 chr4:99064573 C4orf37 0.56 4.45 0.37 1.9e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 1.000 rs56046246 chr5:93531545 T/G cg25358565 chr5:93447407 FAM172A 0.93 7.91 0.58 1.22e-12 Diabetic retinopathy; TGCT cis rs12893668 0.703 rs55751606 chr14:104028806 G/A cg26031613 chr14:104095156 KLC1 -0.56 -4.7 -0.39 6.83e-6 Reticulocyte count; TGCT cis rs250677 0.687 rs10040624 chr5:148437579 A/G cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs734999 0.588 rs2843403 chr1:2529097 T/C cg18854424 chr1:2615690 NA -0.5 -5.78 -0.46 5.64e-8 Ulcerative colitis; TGCT cis rs6684514 1.000 rs2277871 chr1:156246742 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs3751972 1.000 rs3751972 chr17:26206414 C/A cg02948944 chr17:26242737 NA 0.48 6.89 0.53 2.44e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs473651 0.935 rs578510 chr2:239343140 C/T cg18131467 chr2:239335373 ASB1 1.02 15.09 0.8 7.51e-30 Multiple system atrophy; TGCT cis rs4730250 0.707 rs4730222 chr7:106810293 G/C cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.6e-8 Osteoarthritis; TGCT cis rs2050392 0.792 rs303434 chr10:30714440 G/A cg18806716 chr10:30721971 MAP3K8 -0.48 -5.53 -0.44 1.84e-7 Inflammatory bowel disease; TGCT cis rs896854 0.517 rs896851 chr8:95950251 T/C cg16049864 chr8:95962084 TP53INP1 -0.55 -6.05 -0.48 1.55e-8 Type 2 diabetes; TGCT cis rs96067 0.711 rs4653164 chr1:36627542 A/G cg07093915 chr1:36184400 C1orf216 0.47 4.9 0.4 2.94e-6 Corneal structure; TGCT cis rs66887589 0.592 rs2175383 chr4:120215836 C/A cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.16e-5 Diastolic blood pressure; TGCT trans rs1496653 0.602 rs34619482 chr3:23374278 A/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1887596 0.624 rs9551298 chr13:27152527 G/A cg01312412 chr13:27282625 NA 0.27 4.78 0.39 4.81e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs548181 0.736 rs1941558 chr11:125425606 C/T cg03464685 chr11:125439445 EI24 1.37 10.56 0.69 5.45e-19 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9894429 0.646 rs6565612 chr17:79602820 C/T cg21028142 chr17:79581711 NPLOC4 -0.28 -5.71 -0.46 8.05e-8 Eye color traits; TGCT cis rs826838 0.967 rs1719858 chr12:39124505 C/T cg13010199 chr12:38710504 ALG10B -0.64 -5.07 -0.41 1.39e-6 Heart rate; TGCT cis rs7104764 1.000 rs7128029 chr11:244141 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs6089829 0.962 rs4809462 chr20:61661560 A/G cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs600231 0.708 rs602838 chr11:65253247 T/G cg17120908 chr11:65337727 SSSCA1 -0.56 -5.23 -0.42 7.04e-7 Bone mineral density; TGCT cis rs3540 0.554 rs113942266 chr15:91072990 A/G cg22089800 chr15:90895588 ZNF774 -0.76 -7.98 -0.58 8.23e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs1475911 0.656 rs9980065 chr21:43528072 G/A cg24372256 chr21:43528868 UMODL1;C21orf128 -0.34 -5.53 -0.44 1.83e-7 IgG glycosylation; TGCT cis rs7412746 0.611 rs4970985 chr1:150887442 C/T cg09365446 chr1:150670422 GOLPH3L -0.34 -4.69 -0.39 7.14e-6 Melanoma; TGCT cis rs483180 0.511 rs496195 chr1:120207182 A/G cg19096424 chr1:120255104 PHGDH -0.56 -5.24 -0.43 6.8e-7 Macular telangiectasia type 2; TGCT cis rs8044995 0.563 rs3743743 chr16:68397775 C/T cg05110241 chr16:68378359 PRMT7 -0.36 -4.46 -0.37 1.84e-5 Schizophrenia; TGCT cis rs6831352 0.918 rs2602891 chr4:100043284 C/T cg12011299 chr4:100065546 ADH4 0.42 4.99 0.41 2e-6 Alcohol dependence; TGCT cis rs2692947 0.537 rs11677429 chr2:96193061 C/T cg23100626 chr2:96804247 ASTL 0.45 5.33 0.43 4.5e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7513165 0.551 rs11240688 chr1:204134522 C/T cg12731349 chr1:204159619 KISS1 0.47 4.69 0.39 7e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs9811920 0.965 rs10222474 chr3:99862551 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.42 -4.79 -0.4 4.69e-6 Axial length; TGCT cis rs7809950 0.530 rs111865019 chr7:106812246 A/G cg23024343 chr7:107201750 COG5 -0.37 -5.29 -0.43 5.37e-7 Coronary artery disease; TGCT cis rs34526934 0.608 rs34720456 chr2:177027292 G/A cg26754761 chr2:177040938 NA -0.28 -5.22 -0.42 7.15e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs2836974 0.604 rs2854727 chr21:40713787 A/G cg17971929 chr21:40555470 PSMG1 0.59 5.33 0.43 4.4e-7 Cognitive function; TGCT cis rs1552244 1.000 rs6772315 chr3:10113644 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs13108904 0.934 rs13125338 chr4:1278435 A/C cg05665937 chr4:1216051 CTBP1 0.25 4.75 0.39 5.64e-6 Obesity-related traits; TGCT cis rs9372498 0.505 rs62422250 chr6:118990182 T/C cg07617317 chr6:118971624 C6orf204 0.46 4.44 0.37 1.98e-5 Diastolic blood pressure; TGCT cis rs739401 0.611 rs7109088 chr11:3027485 G/T cg25174290 chr11:3078921 CARS 0.5 4.79 0.4 4.6e-6 Longevity; TGCT trans rs208520 0.661 rs704519 chr6:66801136 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.75 -0.69 1.87e-19 Exhaled nitric oxide output; TGCT cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg11890956 chr21:40555474 PSMG1 1.12 12.23 0.74 4.65e-23 Cognitive function; TGCT cis rs2072499 0.833 rs2251847 chr1:156204047 G/A cg06970220 chr1:156163860 SLC25A44 0.72 5.85 0.46 4.14e-8 Testicular germ cell tumor; TGCT cis rs6076065 0.748 rs2281431 chr20:23399304 C/G cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs899997 1.000 rs11629824 chr15:79005524 T/G cg04896959 chr15:78267971 NA 0.36 5.57 0.45 1.52e-7 Coronary artery disease or large artery stroke; TGCT cis rs9467773 0.804 rs2073526 chr6:26374658 C/T cg07107628 chr6:27210934 NA 0.16 4.48 0.37 1.68e-5 Intelligence (multi-trait analysis); TGCT cis rs11696501 0.739 rs6073822 chr20:44251880 A/G cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs2675662 0.525 rs12264025 chr10:75494450 A/G cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Psoriasis vulgaris;Psoriasis; TGCT cis rs6684514 0.961 rs11264463 chr1:156242806 A/G cg16558208 chr1:156270281 VHLL 0.44 8.92 0.63 5.19e-15 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg09060608 chr5:178986726 RUFY1 -0.61 -7.46 -0.56 1.28e-11 Lung cancer; TGCT cis rs78487399 0.808 rs13409687 chr2:43701151 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10992471 0.598 rs2398751 chr9:95206240 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.63 6.25 0.49 5.98e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs763014 0.966 rs15564 chr16:677854 G/T cg07343612 chr16:622815 PIGQ -0.42 -8.44 -0.6 6.97e-14 Height; TGCT cis rs7590720 0.840 rs705648 chr2:216933792 C/T cg12620499 chr2:216877984 MREG 0.77 7.37 0.55 2.14e-11 Alcohol dependence; TGCT cis rs1163251 0.837 rs592762 chr1:120247355 A/G cg19096424 chr1:120255104 PHGDH 0.6 5.93 0.47 2.76e-8 Blood metabolite levels; TGCT cis rs941408 0.515 rs878893 chr19:2781325 A/G cg06609049 chr19:2785107 THOP1 1.16 13.03 0.76 5.49e-25 Total cholesterol levels; TGCT cis rs8103278 1.000 rs35302007 chr19:46219145 G/C cg11657440 chr19:46296263 DMWD -0.56 -5.4 -0.44 3.21e-7 Coronary artery disease; TGCT cis rs7829975 0.688 rs7837587 chr8:8378992 T/C cg08975724 chr8:8085496 FLJ10661 0.64 6.03 0.48 1.77e-8 Mood instability; TGCT cis rs858239 0.730 rs858290 chr7:23248036 A/G cg05602783 chr7:23145260 KLHL7 -0.64 -5.39 -0.44 3.41e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6088590 0.687 rs8115656 chr20:33282780 G/C cg06115741 chr20:33292138 TP53INP2 0.56 4.7 0.39 6.83e-6 Coronary artery disease; TGCT trans rs77457752 0.525 rs1923350 chr9:13898880 T/A cg23609682 chr1:3070786 PRDM16 0.5 6.79 0.52 4.09e-10 Breast cancer; TGCT cis rs9650657 0.530 rs6982381 chr8:10952500 A/T cg03192020 chr8:11204681 TDH -0.51 -4.52 -0.38 1.41e-5 Neuroticism; TGCT cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg01719998 chr16:89642051 CPNE7 0.45 4.5 0.37 1.52e-5 Vitiligo; TGCT cis rs11690935 1.000 rs312925 chr2:172563922 G/A cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.83 -0.76 1.7e-24 Schizophrenia; TGCT cis rs10504229 0.683 rs11781690 chr8:58132931 C/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs35160687 0.901 rs67903513 chr2:86512099 A/C cg12542933 chr2:85804724 VAMP8 0.4 4.76 0.39 5.24e-6 Night sleep phenotypes; TGCT cis rs10927875 0.632 rs2862162 chr1:16142960 A/C cg21385522 chr1:16154831 NA 0.95 15.27 0.81 2.89e-30 Dilated cardiomyopathy; TGCT cis rs4325129 0.677 rs4656836 chr1:159500338 A/G cg07417683 chr1:159440267 NA -0.37 -4.69 -0.39 7.09e-6 Obesity-related traits; TGCT cis rs9952991 0.941 rs2014857 chr18:12774326 C/T cg23544223 chr18:12777786 NA 0.63 6.02 0.48 1.85e-8 Inflammatory skin disease; TGCT cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg10047753 chr17:41438598 NA 0.96 9.86 0.66 2.71e-17 Menopause (age at onset); TGCT cis rs4689388 0.890 rs3821941 chr4:6286954 A/G cg00701064 chr4:6280414 WFS1 0.45 5.98 0.47 2.18e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7937682 0.889 rs1789359 chr11:111475995 T/A cg09085632 chr11:111637200 PPP2R1B -1.05 -11.39 -0.72 5.21e-21 Primary sclerosing cholangitis; TGCT cis rs7824557 0.564 rs2572386 chr8:11236975 A/G cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs10791097 0.694 rs61910787 chr11:130744473 G/A cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9788682 0.747 rs16969894 chr15:78776456 C/T cg24631222 chr15:78858424 CHRNA5 0.61 4.51 0.38 1.5e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs1801251 0.964 rs6748027 chr2:233629552 T/C cg08000102 chr2:233561755 GIGYF2 0.63 6.49 0.5 1.88e-9 Coronary artery disease; TGCT cis rs9341808 0.539 rs2490253 chr6:80895870 T/C cg08355045 chr6:80787529 NA 0.3 5.07 0.41 1.44e-6 Sitting height ratio; TGCT cis rs7943191 0.810 rs7942991 chr11:62337203 A/G cg11742103 chr11:62369870 EML3;MTA2 -0.51 -5.92 -0.47 2.88e-8 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg22764044 chr5:178986830 RUFY1 0.43 4.57 0.38 1.17e-5 Lung cancer; TGCT cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg20637647 chr7:64974828 NA 0.92 5.35 0.43 4.11e-7 Diabetic kidney disease; TGCT cis rs12134133 1.000 rs7543117 chr1:207438696 T/C cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7829975 0.593 rs2979241 chr8:8303353 G/C cg08975724 chr8:8085496 FLJ10661 0.54 4.92 0.4 2.73e-6 Mood instability; TGCT cis rs10927875 0.632 rs2862162 chr1:16142960 A/C cg14742211 chr1:16348397 CLCNKA 0.19 4.57 0.38 1.16e-5 Dilated cardiomyopathy; TGCT cis rs11098499 1.000 rs35643470 chr4:120184948 T/C cg09307838 chr4:120376055 NA 0.49 4.52 0.38 1.43e-5 Corneal astigmatism; TGCT cis rs8078723 0.966 rs2227322 chr17:38171668 C/G cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs72627509 0.501 rs13101682 chr4:57735358 G/A cg26694713 chr4:57773883 REST 0.58 5.91 0.47 3.12e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7147624 1.000 rs11848209 chr14:66022832 T/A cg03016385 chr14:66212404 NA -0.49 -7.08 -0.54 9.33e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7178572 0.889 rs907388 chr15:77828668 G/A cg22256960 chr15:77711686 NA -0.95 -10.78 -0.7 1.59e-19 Type 2 diabetes; TGCT cis rs12261331 1 rs12261331 chr10:82287527 C/T cg01528321 chr10:82214614 TSPAN14 -0.95 -5.94 -0.47 2.69e-8 Post bronchodilator FEV1; TGCT cis rs2729354 0.729 rs2581923 chr11:57249991 C/T cg24343310 chr11:57249947 NA 0.28 4.61 0.38 9.8200000000000008e-06 Blood protein levels; TGCT cis rs7584330 0.518 rs6715245 chr2:238445803 C/T cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs2204008 0.837 rs2127955 chr12:37969194 A/G cg26384229 chr12:38710491 ALG10B 0.71 6.21 0.49 7.18e-9 Bladder cancer; TGCT cis rs782590 0.902 rs782601 chr2:55848244 T/C cg03859395 chr2:55845619 SMEK2 0.9 11.04 0.7 3.81e-20 Metabolic syndrome; TGCT cis rs34638657 0.732 rs11866711 chr16:82201038 A/C cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs9357506 0.967 rs4714929 chr6:46309940 A/T cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs7824557 0.767 rs28507159 chr8:11166076 C/T cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs732765 0.734 rs12882425 chr14:75189226 A/T cg06637938 chr14:75390232 RPS6KL1 -0.57 -5.03 -0.41 1.69e-6 Non-small cell lung cancer; TGCT cis rs651907 0.535 rs13084113 chr3:101534039 C/G cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.5 -0.5 1.8e-9 Colorectal cancer; TGCT cis rs7178424 0.743 rs8032681 chr15:62162243 T/C cg00456672 chr15:62358751 C2CD4A -0.31 -4.72 -0.39 6.37e-6 Height; TGCT cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg11062466 chr8:58055876 NA 0.39 6.0 0.47 2.03e-8 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg09904177 chr6:26538194 HMGN4 0.66 6.33 0.49 3.99e-9 Intelligence (multi-trait analysis); TGCT cis rs9788682 0.748 rs2456020 chr15:78868398 C/T cg24631222 chr15:78858424 CHRNA5 0.81 6.22 0.49 7.06e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs734999 0.549 rs6667564 chr1:2520302 T/C cg18854424 chr1:2615690 NA 0.49 5.72 0.46 7.65e-8 Ulcerative colitis; TGCT cis rs12541335 0.615 rs4872464 chr8:22153381 G/A cg07298985 chr8:22133076 PIWIL2 0.33 5.02 0.41 1.77e-6 Hypertriglyceridemia; TGCT cis rs4727027 0.704 rs12535154 chr7:148895304 G/A cg23583168 chr7:148888333 NA -0.83 -11.12 -0.71 2.36e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12360000 0.797 rs12768776 chr10:1901587 C/T cg26364871 chr10:1889757 NA 0.41 4.64 0.38 8.81e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs9394841 0.667 rs3747750 chr6:41760372 C/G cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs9948 0.786 rs62156227 chr2:97417942 C/A cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs1801239 1.000 rs17343073 chr10:16932196 A/T cg00939682 chr10:16933505 CUBN 0.47 4.46 0.37 1.79e-5 Urinary albumin-to-creatinine ratio in non-diabetics;Urinary albumin excretion; TGCT cis rs2637266 0.703 rs12252157 chr10:78449521 G/A cg18941641 chr10:78392320 NA 0.4 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs7412746 0.658 rs11204750 chr1:150939744 C/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.72 0.39 6.28e-6 Melanoma; TGCT cis rs7829975 0.840 rs572366 chr8:8578794 A/T cg08975724 chr8:8085496 FLJ10661 0.57 4.91 0.4 2.86e-6 Mood instability; TGCT cis rs7208859 0.623 rs11657391 chr17:29194287 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3806843 0.608 rs246042 chr5:140330967 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs4654899 0.931 rs10799679 chr1:21341776 A/G cg01072550 chr1:21505969 NA -0.5 -7.97 -0.58 8.84e-13 Superior frontal gyrus grey matter volume; TGCT cis rs4975709 0.544 rs4975748 chr5:1866025 G/A cg04156016 chr5:1868137 NA 0.36 5.32 0.43 4.62e-7 Cardiovascular disease risk factors; TGCT trans rs877282 0.898 rs12357995 chr10:765739 T/C cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs427394 0.664 rs274697 chr5:6731477 A/C cg10857441 chr5:6722123 POLS -0.29 -7.23 -0.54 4.25e-11 Menopause (age at onset); TGCT cis rs7572733 0.534 rs771009 chr2:198691082 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs7027203 0.576 rs7851269 chr9:96540530 C/T cg14598338 chr9:96623480 NA 0.5 7.36 0.55 2.2e-11 DNA methylation (variation); TGCT cis rs7937682 0.562 rs527847 chr11:111369132 A/C cg09085632 chr11:111637200 PPP2R1B 0.66 6.36 0.5 3.49e-9 Primary sclerosing cholangitis; TGCT cis rs7091068 0.566 rs1326220 chr10:95486155 G/A cg20715218 chr10:95462985 C10orf4 0.52 4.64 0.38 8.72e-6 Urinary tract infection frequency; TGCT cis rs7806994 1 rs7806994 chr7:56139505 A/T cg21096502 chr7:56174374 CHCHD2 -0.88 -6.62 -0.51 9.63e-10 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs7100689 0.784 rs3120977 chr10:82075324 C/G cg01528321 chr10:82214614 TSPAN14 0.8 7.92 0.58 1.15e-12 Post bronchodilator FEV1; TGCT cis rs1129187 0.755 rs2296804 chr6:42931261 C/G cg02353165 chr6:42928485 GNMT 0.8 7.13 0.54 7.19e-11 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs769267 0.931 rs2965197 chr19:19470910 C/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.63 -5.13 -0.42 1.07e-6 Tonsillectomy; TGCT cis rs9913156 0.841 rs56239958 chr17:4600280 G/C cg23387401 chr17:4582204 PELP1 0.31 4.68 0.39 7.44e-6 Lymphocyte counts; TGCT cis rs11190604 0.731 rs10883480 chr10:102163821 G/T cg16342193 chr10:102329863 NA 0.39 5.0 0.41 1.91e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2836974 0.931 rs12151994 chr21:40690397 A/C cg17971929 chr21:40555470 PSMG1 0.96 8.52 0.61 4.51e-14 Cognitive function; TGCT cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7213347 0.707 rs216181 chr17:2172753 A/T cg13315690 chr17:1944831 OVCA2;DPH1 0.39 4.84 0.4 3.75e-6 Total body bone mineral density; TGCT cis rs78487399 0.808 rs6751161 chr2:43752548 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.02 -0.41 1.75e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs939658 0.805 rs35462901 chr15:79442201 C/T cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs1008375 1.000 rs7659718 chr4:17638020 A/C cg18681998 chr4:17616180 MED28 1.07 11.98 0.73 1.97e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28595532 0.920 rs115464801 chr4:119730673 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.04 0.48 1.68e-8 Electroencephalogram traits; TGCT trans rs3780486 0.757 rs10813949 chr9:33123464 G/A cg04842962 chr6:43655489 MRPS18A 1.19 14.71 0.8 5.62e-29 IgG glycosylation; TGCT cis rs6893807 0.620 rs34483452 chr5:87986314 C/A cg24804195 chr5:87968844 LOC645323 0.73 4.77 0.39 5.08e-6 Body mass index; TGCT cis rs7666738 0.830 rs13137859 chr4:99050319 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6460942 0.915 rs62448594 chr7:12442229 C/G cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs2455799 0.559 rs1597068 chr3:15913363 G/A cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs7829975 0.711 rs12682352 chr8:8646246 A/G cg15556689 chr8:8085844 FLJ10661 0.71 6.61 0.51 1.01e-9 Mood instability; TGCT cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs10479542 0.766 rs7733389 chr5:178974997 C/T cg19626725 chr5:178986131 RUFY1 0.45 5.93 0.47 2.81e-8 Lung cancer; TGCT cis rs7072216 0.763 rs6584198 chr10:100169906 G/C cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg11502198 chr6:26597334 ABT1 0.53 4.9 0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT cis rs17767294 0.708 rs72847356 chr6:27825594 C/A cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs713587 0.713 rs11125884 chr2:25239264 C/T cg15423357 chr2:25149977 NA 0.58 5.91 0.47 3.05e-8 Body mass index in non-asthmatics; TGCT cis rs2153535 0.580 rs2327067 chr6:8518482 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs9329289 0.510 rs10903785 chr10:2550063 C/T cg07014206 chr10:2547000 NA -0.28 -4.64 -0.38 8.6e-6 Age-related hearing impairment; TGCT cis rs10992471 1.000 rs10992471 chr9:95559505 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.62 6.48 0.5 1.93e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12477438 0.572 rs10170063 chr2:99655639 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs6089584 0.888 rs6061979 chr20:60617141 C/G cg16423285 chr20:60520624 NA -0.61 -6.57 -0.51 1.23e-9 Body mass index; TGCT cis rs2758596 0.850 rs2842879 chr1:156163695 G/T cg25208724 chr1:156163844 SLC25A44 0.83 5.04 0.41 1.61e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs1218582 0.661 rs4845695 chr1:154911798 A/G cg06221963 chr1:154839813 KCNN3 -0.7 -11.65 -0.72 1.22e-21 Prostate cancer; TGCT cis rs9330316 0.632 rs2060402 chr2:110329104 C/G cg25199208 chr2:109402912 CCDC138 -0.42 -4.56 -0.38 1.19e-5 Schizophrenia; TGCT cis rs769267 0.930 rs892021 chr19:19613480 T/C cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs2463822 0.583 rs7129536 chr11:62030829 C/T cg06239285 chr11:62104954 ASRGL1 -0.86 -5.41 -0.44 3.08e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs4332037 0.539 rs1533827 chr7:2074290 A/G cg25834613 chr7:1915315 MAD1L1 0.53 5.44 0.44 2.78e-7 Bipolar disorder; TGCT trans rs941408 1.000 rs759068 chr19:2792566 G/A cg19676328 chr12:49525230 TUBA1B -0.77 -7.88 -0.58 1.43e-12 Total cholesterol levels; TGCT cis rs617219 0.671 rs2607144 chr5:78556798 G/T cg09550809 chr5:78407562 BHMT 0.42 5.71 0.46 7.98e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4862750 0.794 rs7692427 chr4:187901727 G/A cg11301795 chr4:187892539 NA -0.3 -4.46 -0.37 1.83e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs3213961 0.554 rs8256 chr2:33789068 C/G cg04131969 chr2:33951647 MYADML 0.68 5.31 0.43 4.9e-7 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs4788570 0.566 rs16973112 chr16:71501274 T/C cg06353428 chr16:71660113 MARVELD3 -1.32 -7.86 -0.58 1.6e-12 Intelligence (multi-trait analysis); TGCT cis rs16866061 1.000 rs1568750 chr2:225342597 A/T cg12698349 chr2:225449008 CUL3 0.96 9.45 0.65 2.69e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs3916 1.000 rs3916 chr12:121177272 G/C cg21892295 chr12:121157589 UNC119B -0.22 -4.44 -0.37 1.95e-5 Urinary metabolites (H-NMR features); TGCT cis rs2180341 1.000 rs6569478 chr6:127598619 G/A cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT trans rs916888 0.773 rs199443 chr17:44819565 C/T cg10053473 chr17:62856997 LRRC37A3 -0.46 -6.76 -0.52 4.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7582180 0.764 rs1946799 chr2:100921136 C/A cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.41 2.55e-6 Obesity-related traits; TGCT cis rs362272 0.525 rs910568 chr4:3307373 A/G cg22655196 chr4:3374909 RGS12 0.23 4.62 0.38 9.41e-6 Serum sulfate level; TGCT cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg06238570 chr21:40685208 BRWD1 0.68 6.36 0.5 3.5e-9 Cognitive function; TGCT cis rs9291683 0.530 rs998675 chr4:9948829 A/G cg11266682 chr4:10021025 SLC2A9 0.64 8.48 0.61 5.75e-14 Bone mineral density; TGCT cis rs3617 0.573 rs12492391 chr3:52912296 C/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.84 -0.4 3.85e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2180341 0.781 rs6913350 chr6:127570560 C/T cg27446573 chr6:127587934 RNF146 0.91 8.5 0.61 5.12e-14 Breast cancer; TGCT cis rs7826238 0.566 rs2945886 chr8:8148270 C/G cg15556689 chr8:8085844 FLJ10661 0.87 8.49 0.61 5.45e-14 Systolic blood pressure; TGCT cis rs2180341 0.538 rs4577822 chr6:127712911 T/G cg24812749 chr6:127587940 RNF146 0.61 5.39 0.44 3.45e-7 Breast cancer; TGCT cis rs6998277 0.553 rs6468837 chr8:103602767 A/G cg10187029 chr8:103597600 NA 0.51 9.27 0.64 7.41e-16 Migraine; TGCT cis rs7804356 1.000 rs6956088 chr7:26835727 T/A cg03456212 chr7:26904342 SKAP2 -0.61 -4.67 -0.39 7.59e-6 Type 1 diabetes; TGCT cis rs6589563 0.609 rs57641217 chr11:116632956 C/T cg01124546 chr11:117515332 DSCAML1 -0.45 -4.93 -0.41 2.54e-6 Eosinophil counts; TGCT cis rs12950390 0.853 rs8078052 chr17:45859434 A/G cg24803719 chr17:45855879 NA -0.49 -5.03 -0.41 1.64e-6 IgG glycosylation; TGCT cis rs6754311 0.689 rs191079 chr2:136633771 T/C cg07169764 chr2:136633963 MCM6 0.65 6.06 0.48 1.5e-8 Mosquito bite size; TGCT cis rs2243480 1.000 rs1715235 chr7:65488394 T/C cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs13202913 0.733 rs13215869 chr6:151803659 G/A cg03627880 chr6:151815985 C6orf97 -0.69 -6.43 -0.5 2.53e-9 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg24549020 chr5:56110836 MAP3K1 0.67 5.69 0.45 8.82e-8 Initial pursuit acceleration; TGCT cis rs5769765 0.862 rs9616380 chr22:50312225 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg21672276 chr3:44754072 ZNF502 -0.53 -6.24 -0.49 6.45e-9 Depressive symptoms; TGCT cis rs4665809 1.000 rs10182857 chr2:26344411 C/T cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs7213347 0.707 rs9898390 chr17:2177484 C/G cg13315690 chr17:1944831 OVCA2;DPH1 -0.37 -4.7 -0.39 6.76e-6 Total body bone mineral density; TGCT cis rs9911578 0.967 rs7222789 chr17:56819853 C/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.897 rs6446252 chr3:48911125 C/T cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs13191362 0.935 rs34709632 chr6:163048380 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.03 7.35 0.55 2.37e-11 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs265548 0.608 rs265545 chr19:17903465 C/T cg21960279 chr19:17905606 B3GNT3 0.48 5.3 0.43 5.08e-7 Tumor biomarkers; TGCT cis rs9916302 0.706 rs2338799 chr17:37513941 G/A cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs350251 0.899 rs350277 chr16:12232547 C/T cg01574788 chr16:12184133 SNX29 0.34 4.48 0.37 1.67e-5 Intelligence (multi-trait analysis); TGCT cis rs11098499 0.566 rs7664440 chr4:120578540 A/G cg09307838 chr4:120376055 NA 0.65 6.29 0.49 4.94e-9 Corneal astigmatism; TGCT cis rs10779751 0.575 rs2791655 chr1:11128654 A/G cg08854313 chr1:11322531 MTOR -0.76 -6.62 -0.51 9.61e-10 Body mass index; TGCT cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg11635101 chr7:2050016 MAD1L1 -0.21 -4.47 -0.37 1.71e-5 Longevity;Endometriosis; TGCT cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg10047753 chr17:41438598 NA 0.9 8.32 0.6 1.37e-13 Menopause (age at onset); TGCT cis rs4665809 0.941 rs11126336 chr2:26245931 C/T cg04944784 chr2:26401820 FAM59B -0.65 -5.91 -0.47 3.04e-8 Gut microbiome composition (summer); TGCT cis rs4595586 0.545 rs7294600 chr12:39373416 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7666738 0.609 rs35214820 chr4:98864692 G/A cg05340658 chr4:99064831 C4orf37 0.57 6.05 0.48 1.61e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2072499 0.932 rs2736613 chr1:156196016 T/C cg06970220 chr1:156163860 SLC25A44 0.74 5.94 0.47 2.71e-8 Testicular germ cell tumor; TGCT cis rs1568889 0.938 rs11601602 chr11:28233768 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.84 8.67 0.61 2.05e-14 Bipolar disorder; TGCT cis rs1218582 0.772 rs4845689 chr1:154885524 A/G cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs453301 0.653 rs11784393 chr8:8903134 C/T cg06636001 chr8:8085503 FLJ10661 0.86 7.66 0.57 4.68e-12 Joint mobility (Beighton score); TGCT cis rs6840360 0.518 rs4696082 chr4:152286935 T/A cg17479576 chr4:152424074 FAM160A1 -0.45 -4.72 -0.39 6.27e-6 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg22800045 chr5:56110881 MAP3K1 0.54 4.49 0.37 1.58e-5 Initial pursuit acceleration; TGCT cis rs6964587 1.000 rs6969536 chr7:91689351 C/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg17971929 chr21:40555470 PSMG1 0.97 9.51 0.65 1.95e-16 Cognitive function; TGCT cis rs1008375 1.000 rs56308330 chr4:17643050 G/A cg10189774 chr4:17578691 LAP3 0.58 5.26 0.43 6.24e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs4332037 0.901 rs7791899 chr7:1935988 T/C cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs2288884 1.000 rs80278704 chr19:52549183 G/A cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg09436375 chr6:42928200 GNMT 0.42 5.41 0.44 3.16e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6860806 0.632 rs4330455 chr5:131586349 T/C cg24060327 chr5:131705240 SLC22A5 -0.56 -5.6 -0.45 1.34e-7 Breast cancer; TGCT cis rs7772486 0.754 rs9373476 chr6:146139741 C/G cg23711669 chr6:146136114 FBXO30 0.89 9.8 0.66 3.89e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.71 -0.39 6.39e-6 Prudent dietary pattern; TGCT cis rs8008270 0.689 rs7158115 chr14:53418339 G/C cg01926858 chr14:53619558 DDHD1 -0.74 -4.73 -0.39 5.89e-6 Prostate cancer; TGCT cis rs941408 1.000 rs1736183 chr19:2809672 A/G cg06609049 chr19:2785107 THOP1 0.81 8.22 0.59 2.33e-13 Total cholesterol levels; TGCT cis rs9611519 0.579 rs8136274 chr22:41415311 T/C cg06634786 chr22:41940651 POLR3H -0.49 -4.54 -0.38 1.33e-5 Neuroticism; TGCT cis rs950169 0.881 rs34591918 chr15:84950833 C/T cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT trans rs877282 0.891 rs34652870 chr10:772218 T/C cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs9914544 0.545 rs2892016 chr17:18786776 C/T cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.06e-6 Educational attainment (years of education); TGCT cis rs7216064 1.000 rs9913471 chr17:65874495 C/T cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs11098499 0.754 rs10518300 chr4:120249499 G/T cg24670566 chr4:120433619 PDE5A -0.27 -5.22 -0.42 7.23e-7 Corneal astigmatism; TGCT cis rs9790314 0.905 rs7633186 chr3:161003124 A/G cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs514406 0.505 rs6703127 chr1:53180565 C/T cg25767906 chr1:53392781 SCP2 -0.47 -5.35 -0.43 4.02e-7 Monocyte count; TGCT cis rs1775715 0.707 rs2808087 chr10:32146444 C/G cg14930904 chr10:32216787 ARHGAP12 0.53 5.1 0.42 1.22e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2742417 1.000 rs767280 chr3:45771601 C/G cg04837898 chr3:45731254 SACM1L -0.53 -5.52 -0.44 1.92e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs908922 0.676 rs7529441 chr1:152531629 A/G cg20991723 chr1:152506922 NA -0.44 -5.95 -0.47 2.51e-8 Hair morphology; TGCT cis rs9549367 0.707 rs9549353 chr13:113843427 G/A cg00898013 chr13:113819073 PROZ -0.53 -6.94 -0.53 1.89e-10 Platelet distribution width; TGCT cis rs7727544 0.735 rs274559 chr5:131720070 A/G cg24060327 chr5:131705240 SLC22A5 0.58 6.53 0.51 1.5e-9 Blood metabolite levels; TGCT cis rs7633770 0.841 rs11130100 chr3:46679198 A/T cg11219411 chr3:46661640 NA -0.34 -4.72 -0.39 6.31e-6 Coronary artery disease; TGCT cis rs8014204 0.773 rs2241275 chr14:75251440 C/T cg06637938 chr14:75390232 RPS6KL1 -0.71 -6.82 -0.52 3.56e-10 Caffeine consumption; TGCT cis rs5769765 0.671 rs138817 chr22:50163058 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.61 0.45 1.27e-7 Schizophrenia; TGCT cis rs6088580 0.634 rs6087587 chr20:33058628 G/T cg06115741 chr20:33292138 TP53INP2 0.52 4.47 0.37 1.75e-5 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.683 rs1495866 chr8:58141128 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg06238570 chr21:40685208 BRWD1 0.59 5.25 0.43 6.37e-7 Cognitive function; TGCT cis rs2239547 0.522 rs7652131 chr3:52997154 C/T cg11645453 chr3:52864694 ITIH4 0.32 5.27 0.43 5.93e-7 Schizophrenia; TGCT cis rs7312774 0.609 rs2374656 chr12:107380411 A/C cg16260113 chr12:107380972 MTERFD3 1.21 5.85 0.47 4.03e-8 Severe influenza A (H1N1) infection; TGCT cis rs7666738 0.761 rs1456210 chr4:98645932 T/G cg05340658 chr4:99064831 C4orf37 0.43 5.05 0.41 1.51e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11809207 1.000 rs11809207 chr1:26521140 G/A cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs7681440 0.874 rs1372522 chr4:90765280 A/G cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs7439150 0.954 rs6056 chr4:155488821 C/T cg22130008 chr4:155548532 NA -0.47 -5.73 -0.46 7.32e-8 Fibrinogen levels; TGCT cis rs709400 0.628 rs11623470 chr14:104004810 T/A cg26031613 chr14:104095156 KLC1 0.87 9.64 0.65 9.63e-17 Body mass index; TGCT cis rs778371 0.723 rs1973675 chr2:233636450 C/T cg08000102 chr2:233561755 GIGYF2 -0.73 -8.65 -0.61 2.23e-14 Schizophrenia; TGCT cis rs7584330 0.955 rs6729659 chr2:238385126 T/C cg08992911 chr2:238395768 MLPH 0.66 5.27 0.43 5.8e-7 Prostate cancer; TGCT cis rs554111 0.891 rs671905 chr1:21047092 A/T cg08890418 chr1:21044141 KIF17 0.57 6.22 0.49 7.14e-9 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs2243480 1.000 rs313820 chr7:65574466 A/C cg20637647 chr7:64974828 NA 0.85 4.89 0.4 3e-6 Diabetic kidney disease; TGCT cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg03609598 chr5:56110824 MAP3K1 -0.59 -4.85 -0.4 3.64e-6 Initial pursuit acceleration; TGCT cis rs35160687 0.871 rs2278105 chr2:86466516 A/G cg03171300 chr2:86307199 POLR1A 0.33 5.58 0.45 1.42e-7 Night sleep phenotypes; TGCT trans rs66573146 1.000 rs73202122 chr4:7005594 G/A cg07817883 chr1:32538562 TMEM39B 1.77 8.38 0.6 9.8e-14 Granulocyte percentage of myeloid white cells; TGCT cis rs7937682 0.961 rs552387 chr11:111490047 T/G cg09085632 chr11:111637200 PPP2R1B -0.98 -9.75 -0.66 5.19e-17 Primary sclerosing cholangitis; TGCT cis rs11641365 0.517 rs73262667 chr16:88779753 C/T cg00034003 chr16:88779146 CTU2 0.4 6.09 0.48 1.32e-8 Autism spectrum disorder-related traits; TGCT cis rs6088580 0.634 rs2378134 chr20:32938085 C/T cg08999081 chr20:33150536 PIGU -0.26 -4.96 -0.41 2.26e-6 Glomerular filtration rate (creatinine); TGCT cis rs9583531 0.600 rs1441042 chr13:111365589 T/G cg24331049 chr13:111365604 ING1 0.81 7.89 0.58 1.33e-12 Coronary artery disease; TGCT cis rs8037137 0.915 rs2301825 chr15:91528070 C/G cg22570213 chr15:91497863 RCCD1 0.52 4.89 0.4 3.04e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs9467773 0.869 rs1796521 chr6:26421392 T/C cg05738196 chr6:26577821 NA -0.63 -6.73 -0.52 5.72e-10 Intelligence (multi-trait analysis); TGCT cis rs4788439 0.892 rs17178990 chr16:24921945 C/A cg07626409 chr16:25250191 ZKSCAN2 0.34 4.53 0.38 1.38e-5 Blood metabolite levels; TGCT cis rs6121246 0.567 rs6060260 chr20:30192907 C/T cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg12386194 chr3:101231763 SENP7 0.61 5.75 0.46 6.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17401966 0.838 rs4529713 chr1:10307295 A/G cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs1371867 0.513 rs1542812 chr8:101207064 G/A cg06636551 chr8:101224915 SPAG1 0.55 8.12 0.59 3.96e-13 Atrioventricular conduction; TGCT cis rs6964587 0.869 rs10256780 chr7:91527176 T/A cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs10992471 0.756 rs7848055 chr9:95115492 A/C cg14631576 chr9:95140430 CENPP -0.29 -4.73 -0.39 6.1e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9291683 0.588 rs6857693 chr4:10018435 G/A cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Bone mineral density; TGCT cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg06634786 chr22:41940651 POLR3H 0.86 8.19 0.59 2.71e-13 Vitiligo; TGCT cis rs9926296 0.605 rs6500453 chr16:89858657 C/G cg03388025 chr16:89894329 SPIRE2 0.48 8.4 0.6 8.77e-14 Vitiligo; TGCT cis rs7635838 0.892 rs9310379 chr3:11434143 C/T cg00170343 chr3:11313890 ATG7 -0.64 -6.08 -0.48 1.39e-8 HDL cholesterol; TGCT cis rs7267979 1.000 rs4815411 chr20:25350223 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs72781680 1.000 rs6710426 chr2:24159288 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs838147 0.537 rs632111 chr19:49208978 A/G cg04599840 chr19:48886497 KDELR1 0.21 4.48 0.37 1.64e-5 Dietary macronutrient intake; TGCT cis rs2334880 0.638 rs35166226 chr16:71443219 T/C cg06353428 chr16:71660113 MARVELD3 -1.26 -7.14 -0.54 6.98e-11 Malaria; TGCT cis rs6582630 0.599 rs1851114 chr12:38424671 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs13242816 0.881 rs35037267 chr7:116117587 A/T cg16553024 chr7:116138462 CAV2 -0.45 -4.81 -0.4 4.32e-6 P wave duration; TGCT cis rs5769707 0.632 rs135871 chr22:50008969 A/G cg05373962 chr22:49881684 NA -0.29 -4.93 -0.4 2.63e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9300255 0.543 rs655293 chr12:123528405 G/A cg00376283 chr12:123451042 ABCB9 0.68 4.95 0.41 2.34e-6 Neutrophil percentage of white cells; TGCT cis rs185694 1.000 rs202083 chr13:30881316 C/T cg07600127 chr13:30881527 KATNAL1 -0.87 -6.77 -0.52 4.55e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs986417 1.000 rs10144805 chr14:60927652 T/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs7223966 1.000 rs8064261 chr17:61705212 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.66 0.39 8.03e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9427116 0.532 rs9426828 chr1:154591489 G/A cg17218026 chr1:154582156 ADAR 0.31 7.97 0.58 8.71e-13 Blood protein levels; TGCT cis rs7552404 1.000 rs4949875 chr1:76173080 G/A cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.830 rs7696568 chr4:99005333 A/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6867032 0.958 rs4463207 chr5:2017118 G/T cg26168224 chr5:2018326 NA 0.44 8.03 0.59 6.26e-13 Gut microbiome composition (winter); TGCT cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.02 -0.67 1.12e-17 Bipolar disorder; TGCT cis rs1008375 0.966 rs1860591 chr4:17577329 A/G cg16339924 chr4:17578868 LAP3 0.75 6.7 0.52 6.41e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1005277 0.579 rs2472175 chr10:38382901 T/G cg17830980 chr10:43048298 ZNF37B -0.85 -10.98 -0.7 5.08e-20 Extrinsic epigenetic age acceleration; TGCT cis rs7772486 0.875 rs9373485 chr6:146401429 A/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.05 8.95 0.63 4.39e-15 Platelet count; TGCT cis rs2760061 0.626 rs1636192 chr1:228124688 A/G cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs13242816 0.881 rs55930206 chr7:116172850 C/T cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs6964587 0.869 rs6979024 chr7:91481512 T/C cg17063962 chr7:91808500 NA -0.86 -9.19 -0.64 1.16e-15 Breast cancer; TGCT cis rs9894429 0.738 rs8077038 chr17:79577127 T/G cg18240062 chr17:79603768 NPLOC4 -0.84 -9.67 -0.66 8.03e-17 Eye color traits; TGCT cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg11644478 chr21:40555479 PSMG1 1.02 11.02 0.7 4.19e-20 Cognitive function; TGCT cis rs4654899 0.795 rs61309203 chr1:21118489 A/T cg01072550 chr1:21505969 NA -0.49 -7.78 -0.57 2.48e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2180341 1.000 rs9375499 chr6:127618072 T/C cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg02953382 chr22:24373134 LOC391322 -0.83 -9.22 -0.64 9.47e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs7613875 0.580 rs12634780 chr3:50043341 A/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.55 -0.61 3.86e-14 Body mass index; TGCT cis rs4843185 0.576 rs380996 chr16:85728813 A/G cg26571870 chr16:85723150 GINS2 0.35 4.47 0.37 1.75e-5 Platelet distribution width; TGCT cis rs2243480 1.000 rs1873494 chr7:65649899 T/C cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs4319547 0.695 rs6488958 chr12:122880704 A/G cg05707623 chr12:122985044 ZCCHC8 -0.57 -4.5 -0.37 1.53e-5 Body mass index; TGCT cis rs11098499 0.954 rs12507964 chr4:120413061 T/A cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs4746818 1.000 rs10823313 chr10:70952115 G/A cg11621586 chr10:70884670 VPS26A 1.21 10.5 0.69 7.7e-19 Left atrial antero-posterior diameter; TGCT cis rs2242116 0.900 rs4683300 chr3:46934292 C/A cg02527881 chr3:46936655 PTH1R -0.3 -5.77 -0.46 5.91e-8 Birth weight; TGCT cis rs1635 0.655 rs1416919 chr6:28302884 T/G cg15743358 chr6:28303923 ZNF323 -1.28 -6.27 -0.49 5.57e-9 Schizophrenia; TGCT cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg07061783 chr6:25882402 NA -0.63 -6.68 -0.51 7.27e-10 Blood metabolite levels; TGCT cis rs9443189 0.570 rs504323 chr6:76294965 A/G cg01950844 chr6:76311363 SENP6 -1.03 -6.5 -0.5 1.77e-9 Prostate cancer; TGCT cis rs10131894 0.611 rs174995 chr14:75434183 T/C cg08847533 chr14:75593920 NEK9 -0.66 -6.32 -0.49 4.36e-9 Coronary artery disease; TGCT trans rs1908814 0.516 rs58869268 chr8:11797095 G/C cg15556689 chr8:8085844 FLJ10661 0.75 7.07 0.54 9.74e-11 Neuroticism; TGCT cis rs9467773 1.000 rs1321481 chr6:26538210 A/T cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs3820928 0.967 rs4675118 chr2:227773157 C/A cg11843606 chr2:227700838 RHBDD1 -0.54 -4.82 -0.4 4.12e-6 Pulmonary function; TGCT cis rs9486719 0.947 rs6916232 chr6:96985959 A/T cg06623918 chr6:96969491 KIAA0776 1.01 8.81 0.62 9.21e-15 Migraine;Coronary artery disease; TGCT trans rs561341 1.000 rs550264 chr17:30317540 G/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs981844 1.000 rs55722886 chr4:154668335 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs1371867 0.846 rs1788189 chr8:101249762 G/T cg06636551 chr8:101224915 SPAG1 0.48 6.57 0.51 1.28e-9 Atrioventricular conduction; TGCT cis rs2456568 0.900 rs2511399 chr11:93682156 C/T cg17595323 chr11:93583763 C11orf90 0.44 5.93 0.47 2.83e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs68170813 0.559 rs78610616 chr7:106951369 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs875971 0.540 rs35510581 chr7:65578777 G/A cg18876405 chr7:65276391 NA -0.41 -6.4 -0.5 2.96e-9 Aortic root size; TGCT cis rs459571 0.959 rs392134 chr9:136909008 G/A cg14405625 chr9:136855902 VAV2 -0.31 -4.64 -0.38 8.85e-6 Platelet distribution width; TGCT cis rs3743266 0.507 rs34092508 chr15:60722979 C/T cg18480781 chr15:60294291 NA 0.6 4.74 0.39 5.71e-6 Menarche (age at onset); TGCT cis rs713587 0.935 rs11676272 chr2:25141538 A/G cg01884057 chr2:25150051 NA 0.39 8.07 0.59 5.03e-13 Body mass index in non-asthmatics; TGCT cis rs3820068 0.581 rs78175477 chr1:15948091 C/G cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.26e-13 Systolic blood pressure; TGCT cis rs7937682 0.824 rs577044 chr11:111490420 G/T cg09085632 chr11:111637200 PPP2R1B -0.98 -9.75 -0.66 5.19e-17 Primary sclerosing cholangitis; TGCT cis rs10484885 0.618 rs292241 chr6:90603505 A/G cg13799429 chr6:90582589 CASP8AP2 -0.4 -4.8 -0.4 4.45e-6 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7805747 0.961 rs73158188 chr7:151415233 C/T cg17611936 chr7:151411526 PRKAG2 0.54 6.72 0.52 5.9e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs36051895 0.632 rs1590803 chr9:5177533 T/C cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.2e-20 Pediatric autoimmune diseases; TGCT cis rs3087591 1.000 rs1123232 chr17:29423989 A/G cg24425628 chr17:29625626 OMG;NF1 0.48 7.46 0.56 1.3e-11 Hip circumference; TGCT cis rs6570726 0.791 rs1509214 chr6:145784606 A/C cg23711669 chr6:146136114 FBXO30 -0.86 -9.64 -0.65 9.5e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9318086 0.901 rs7336730 chr13:24452104 T/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.68 -6.8 -0.52 4.01e-10 Myopia (pathological); TGCT cis rs826838 0.967 rs826876 chr12:39123843 T/C cg26384229 chr12:38710491 ALG10B -0.86 -7.76 -0.57 2.68e-12 Heart rate; TGCT cis rs8062405 1.000 rs7498665 chr16:28883241 A/G cg09754948 chr16:28834200 ATXN2L 0.6 4.46 0.37 1.79e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9549367 0.713 rs1323315 chr13:113859658 T/C cg09473364 chr13:112927190 NA 0.29 4.59 0.38 1.06e-5 Platelet distribution width; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT trans rs11722228 0.508 rs2241473 chr4:10085949 G/A cg26043149 chr18:55253948 FECH 1.14 11.59 0.72 1.68e-21 Gout;Urate levels;Serum uric acid levels; TGCT cis rs8078723 0.966 rs57968500 chr17:38145828 A/G cg17467752 chr17:38218738 THRA 0.55 5.37 0.43 3.68e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs603424 0.512 rs7896618 chr10:102082022 G/A cg22671421 chr10:102507979 PAX2 -0.57 -4.86 -0.4 3.47e-6 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs1692580 0.807 rs263535 chr1:2177727 T/C cg21194808 chr1:2205498 SKI 0.3 5.83 0.46 4.43e-8 Coronary artery disease; TGCT cis rs13191362 0.872 rs73020362 chr6:163005737 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7208859 0.623 rs216433 chr17:28921860 T/C cg04154034 chr17:28927549 LRRC37B2 0.79 4.8 0.4 4.54e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs9486719 1.000 rs13202675 chr6:97028427 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs2658782 0.547 rs10765602 chr11:93048165 G/T cg15737290 chr11:93063684 CCDC67 1.03 10.89 0.7 8.5e-20 Pulmonary function decline; TGCT cis rs344364 0.511 rs911391 chr16:1947016 C/A cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs10791323 0.627 rs2723614 chr11:133705871 T/G cg15485101 chr11:133734466 NA 0.41 5.15 0.42 9.75e-7 Childhood ear infection; TGCT cis rs2153535 0.580 rs969422 chr6:8451780 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg12311346 chr5:56204834 C5orf35 0.68 6.85 0.52 3e-10 Initial pursuit acceleration; TGCT cis rs950169 1.000 rs1911155 chr15:84787635 A/G cg11189052 chr15:85197271 WDR73 0.72 6.09 0.48 1.32e-8 Schizophrenia; TGCT cis rs9430161 0.611 rs72644043 chr1:11033051 T/A cg02454025 chr1:11042201 C1orf127 0.97 11.84 0.73 4.24e-22 Ewing sarcoma; TGCT cis rs17376456 0.542 rs10061069 chr5:93071630 G/C cg25358565 chr5:93447407 FAM172A 0.62 5.89 0.47 3.43e-8 Diabetic retinopathy; TGCT cis rs4819052 0.851 rs914218 chr21:46698445 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1348850 0.567 rs880897 chr2:178532503 C/T cg22681709 chr2:178499509 PDE11A -0.46 -5.95 -0.47 2.58e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7772486 0.875 rs7766463 chr6:146364453 A/G cg23711669 chr6:146136114 FBXO30 0.87 9.53 0.65 1.75e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs16867321 0.527 rs1025126 chr2:181590747 A/G cg12875548 chr2:181044332 NA -0.35 -4.67 -0.39 7.62e-6 Obesity; TGCT cis rs422249 0.547 rs102275 chr11:61557803 T/C cg19610905 chr11:61596333 FADS2 -0.94 -8.99 -0.63 3.5e-15 Trans fatty acid levels; TGCT cis rs8177253 0.665 rs4525863 chr3:133436136 C/A cg01448562 chr3:133502909 NA -0.26 -4.79 -0.4 4.65e-6 Iron status biomarkers; TGCT cis rs4862750 0.872 rs9998173 chr4:187898778 T/A cg11301795 chr4:187892539 NA -0.33 -4.88 -0.4 3.19e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6831352 0.918 rs13107558 chr4:100050200 C/A cg12011299 chr4:100065546 ADH4 -0.38 -5.11 -0.42 1.18e-6 Alcohol dependence; TGCT cis rs4148883 0.689 rs1154415 chr4:99999033 T/C cg12011299 chr4:100065546 ADH4 0.4 5.94 0.47 2.71e-8 Alcohol dependence; TGCT cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs28595532 0.920 rs56302600 chr4:119770162 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs801193 1.000 rs2659915 chr7:66153101 A/G cg18876405 chr7:65276391 NA 0.3 4.69 0.39 7e-6 Aortic root size; TGCT cis rs1949733 0.628 rs2688231 chr4:8490981 G/A cg11789530 chr4:8429930 ACOX3 0.51 4.81 0.4 4.32e-6 Response to antineoplastic agents; TGCT cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2108225 1.000 rs989960 chr7:107445727 C/T cg20438043 chr7:107601757 LAMB1 -0.24 -4.53 -0.38 1.34e-5 Ulcerative colitis; TGCT cis rs2730245 0.527 rs2657362 chr7:158685095 A/G cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs858239 0.601 rs7805206 chr7:23160210 C/T cg05602783 chr7:23145260 KLHL7 -0.69 -6.58 -0.51 1.16e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs12142240 0.738 rs67545510 chr1:46806242 G/T cg00530320 chr1:46809349 NSUN4 0.29 5.95 0.47 2.58e-8 Menopause (age at onset); TGCT cis rs1008375 1.000 rs1974624 chr4:17650281 A/G cg10189774 chr4:17578691 LAP3 0.55 4.9 0.4 2.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17102423 0.594 rs1124751 chr14:65567601 C/A cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.57e-9 Obesity-related traits; TGCT cis rs13256369 0.802 rs13255789 chr8:8562791 T/C cg17143192 chr8:8559678 CLDN23 0.56 5.31 0.43 4.9e-7 Obesity-related traits; TGCT cis rs6952808 0.743 rs4719308 chr7:1877502 T/G cg22963979 chr7:1858916 MAD1L1 -0.31 -4.78 -0.39 4.9e-6 Bipolar disorder and schizophrenia; TGCT cis rs78487399 0.808 rs17039131 chr2:43652398 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.45 -5.35 -0.43 4.03e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12134245 0.776 rs12122066 chr1:92005140 C/T cg25838465 chr1:92012736 NA -0.43 -6.91 -0.53 2.22e-10 Breast cancer; TGCT cis rs6598955 0.671 rs17163866 chr1:26648088 A/G cg04990556 chr1:26633338 UBXN11 0.65 4.54 0.38 1.3e-5 Obesity-related traits; TGCT cis rs2996428 0.667 rs10492942 chr1:3764216 C/T cg13057898 chr1:3703894 LRRC47 0.22 4.68 0.39 7.24e-6 Red cell distribution width; TGCT cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs17001868 1.000 rs73167022 chr22:40797256 A/T cg07138101 chr22:40742427 ADSL 0.69 4.65 0.39 8.38e-6 Mammographic density (dense area); TGCT cis rs11673344 0.523 rs7256380 chr19:37532080 T/C cg08039142 chr19:36980659 ZNF566 0.49 4.5 0.37 1.57e-5 Obesity-related traits; TGCT cis rs3862030 0.839 rs12570859 chr10:104257226 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -4.99 -0.41 2.01e-6 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs10782582 0.532 rs12132503 chr1:76137762 C/G cg10523679 chr1:76189770 ACADM -0.69 -7.16 -0.54 6.4e-11 Daytime sleep phenotypes; TGCT cis rs651907 0.535 rs11716558 chr3:101528481 T/C cg12386194 chr3:101231763 SENP7 0.47 4.7 0.39 6.87e-6 Colorectal cancer; TGCT cis rs9733 0.526 rs6587542 chr1:150907701 G/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Tonsillectomy; TGCT cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg05368731 chr17:41323189 NBR1 1.2 14.59 0.79 1.08e-28 Menopause (age at onset); TGCT cis rs910316 0.967 rs11159121 chr14:75666029 A/T cg11812906 chr14:75593930 NEK9 -0.71 -6.9 -0.53 2.42e-10 Height; TGCT cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg15687855 chr3:44754131 ZNF502 -0.43 -5.26 -0.43 6.04e-7 Depressive symptoms; TGCT cis rs4972806 0.849 rs2857541 chr2:177029086 C/T cg03152288 chr2:177042942 NA 0.6 5.16 0.42 9.57e-7 IgG glycosylation; TGCT cis rs1975974 1.000 rs1985717 chr17:21731807 T/A cg18423549 chr17:21743878 NA -0.54 -4.97 -0.41 2.18e-6 Psoriasis; TGCT cis rs4563143 0.647 rs117442062 chr19:29256823 A/T cg03161606 chr19:29218774 NA 0.59 5.71 0.46 7.95e-8 Methadone dose in opioid dependence; TGCT cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg06212747 chr3:49208901 KLHDC8B 0.66 6.19 0.49 7.94e-9 Menarche (age at onset); TGCT cis rs7666738 0.830 rs1426663 chr4:98990092 T/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9300255 0.602 rs6488864 chr12:123618362 G/C cg00376283 chr12:123451042 ABCB9 0.69 4.89 0.4 3.08e-6 Neutrophil percentage of white cells; TGCT cis rs28595532 0.920 rs17325192 chr4:119780345 A/G cg14228332 chr4:119757509 SEC24D -0.76 -5.17 -0.42 9.28e-7 Cannabis dependence symptom count; TGCT cis rs8177253 0.666 rs8177197 chr3:133469530 G/A cg08048268 chr3:133502702 NA -0.54 -7.22 -0.54 4.68e-11 Iron status biomarkers; TGCT cis rs6754311 0.550 rs10173394 chr2:136522675 C/T cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Mosquito bite size; TGCT cis rs7264396 0.622 rs3787165 chr20:34228946 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.68 -0.39 7.38e-6 Total cholesterol levels; TGCT cis rs7772486 0.875 rs1412080 chr6:146417304 T/C cg05347473 chr6:146136440 FBXO30 0.53 5.03 0.41 1.71e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11190604 1.000 rs10883493 chr10:102208188 A/T cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs899997 1.000 rs11632672 chr15:79044330 A/G cg04896959 chr15:78267971 NA 0.35 5.07 0.41 1.4e-6 Coronary artery disease or large artery stroke; TGCT cis rs4319547 1.000 rs1392236 chr12:123074890 C/G cg23029597 chr12:123009494 RSRC2 -0.31 -5.01 -0.41 1.82e-6 Body mass index; TGCT cis rs9517320 0.534 rs3858778 chr13:99172249 A/C cg07423050 chr13:99094983 FARP1 0.32 6.23 0.49 6.68e-9 Longevity; TGCT trans rs1005277 0.579 rs2505257 chr10:38372664 A/G cg17830980 chr10:43048298 ZNF37B -0.86 -10.91 -0.7 7.74e-20 Extrinsic epigenetic age acceleration; TGCT cis rs832540 0.830 rs252907 chr5:56120646 G/A cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Coronary artery disease; TGCT cis rs2938670 1 rs2938670 chr15:78740688 T/G cg18825076 chr15:78729989 IREB2 -0.33 -5.32 -0.43 4.68e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1;Post bronchodilator FEV1 in COPD;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs514406 0.679 rs541852 chr1:53256834 A/G cg08859206 chr1:53392774 SCP2 0.45 7.01 0.53 1.33e-10 Monocyte count; TGCT cis rs2224391 0.628 rs2773299 chr6:5242169 C/G cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.12 -0.48 1.16e-8 Height; TGCT cis rs2078087 0.790 rs78517564 chr1:183442324 A/C cg16263152 chr1:183287819 NMNAT2 0.41 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs7666738 0.606 rs4577589 chr4:99087858 A/G cg05340658 chr4:99064831 C4orf37 0.44 4.8 0.4 4.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4073582 0.595 rs9326370 chr11:65992008 A/G cg16950941 chr11:66035639 RAB1B 0.59 5.58 0.45 1.42e-7 Gout; TGCT cis rs10504229 0.775 rs72650869 chr8:58157923 T/A cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs10791097 0.720 rs7119425 chr11:130733185 C/T cg05962950 chr11:130786565 SNX19 0.87 10.9 0.7 8.28e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7917772 0.604 rs4917977 chr10:104363119 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7113874 0.569 rs9736791 chr11:8589648 A/G cg14521421 chr11:8862019 ST5 0.28 4.49 0.37 1.58e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs763121 0.925 rs9835 chr22:39130971 A/G cg06022373 chr22:39101656 GTPBP1 0.69 6.58 0.51 1.21e-9 Menopause (age at onset); TGCT cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg11301795 chr4:187892539 NA -0.31 -4.67 -0.39 7.71e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7523273 0.586 rs2761425 chr1:207894033 C/T cg22525895 chr1:207977042 MIR29B2 -0.32 -5.28 -0.43 5.49e-7 Schizophrenia; TGCT cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.7 -6.38 -0.5 3.14e-9 Tonsillectomy; TGCT cis rs2760061 0.598 rs1774755 chr1:228115282 T/G cg02753203 chr1:228287806 NA -0.34 -6.64 -0.51 8.94e-10 Diastolic blood pressure; TGCT cis rs7666738 0.830 rs10440379 chr4:98902822 G/T cg17366294 chr4:99064904 C4orf37 0.67 6.83 0.52 3.3e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2456568 0.548 rs7113080 chr11:93657520 G/A cg16099599 chr11:93583650 C11orf90 -0.39 -4.61 -0.38 9.94e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs57221529 0.600 rs11750269 chr5:666270 G/A cg11887960 chr12:57824829 NA 1.14 9.58 0.65 1.35e-16 Lung disease severity in cystic fibrosis; TGCT cis rs12681287 0.547 rs6471360 chr8:87513469 C/T cg27223183 chr8:87520930 FAM82B 0.95 6.95 0.53 1.81e-10 Caudate activity during reward; TGCT cis rs6088590 1.000 rs12626122 chr20:33425800 A/G cg24642439 chr20:33292090 TP53INP2 0.68 5.9 0.47 3.29e-8 Coronary artery disease; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg14159672 chr1:205819179 PM20D1 0.61 7.32 0.55 2.79e-11 Menarche (age at onset); TGCT cis rs1215050 0.740 rs783936 chr4:98928628 G/T cg05340658 chr4:99064831 C4orf37 -0.44 -5.35 -0.43 4.13e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8051431 0.806 rs4788590 chr16:72020294 G/A cg06353428 chr16:71660113 MARVELD3 0.57 4.54 0.38 1.31e-5 LDL cholesterol levels; TGCT cis rs829418 0.582 rs747662 chr1:21947218 C/G cg03132729 chr1:21947437 RAP1GAP -0.62 -4.68 -0.39 7.32e-6 Neurocognitive impairment in HIV-1 infection (continuous); TGCT cis rs4824093 0.610 rs77128035 chr22:50241024 C/T cg20569369 chr22:51173646 NA 0.27 4.59 0.38 1.09e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs968567 0.501 rs174553 chr11:61575158 A/G cg19610905 chr11:61596333 FADS2 -1.07 -12.03 -0.73 1.43e-22 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg05368731 chr17:41323189 NBR1 1.16 13.76 0.78 1.03e-26 Menopause (age at onset); TGCT cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg01802117 chr1:53393560 SCP2 0.44 5.18 0.42 8.66e-7 Monocyte count; TGCT trans rs2727020 0.521 rs2088526 chr11:49531968 G/A cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Coronary artery disease; TGCT cis rs3815148 0.569 rs12705406 chr7:106792554 A/G cg02696742 chr7:106810147 HBP1 0.67 4.59 0.38 1.08e-5 Osteoarthritis; TGCT cis rs2204008 0.693 rs12372025 chr12:38202028 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.6 0.56 6.23e-12 Bladder cancer; TGCT cis rs6866344 0.570 rs1132336 chr5:178140090 C/T cg03877680 chr5:178157825 ZNF354A 0.77 6.78 0.52 4.28e-10 Neutrophil percentage of white cells; TGCT cis rs2455799 0.586 rs2345739 chr3:15919294 T/G cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs2721195 0.845 rs4244611 chr8:145739924 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 0.88 9.57 0.65 1.38e-16 Age at first birth; TGCT cis rs7666738 0.830 rs28417716 chr4:98864859 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.502 rs11495393 chr12:38341194 T/C cg26384229 chr12:38710491 ALG10B 0.79 6.98 0.53 1.61e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs6088590 1.000 rs6119535 chr20:33442138 A/C cg24642439 chr20:33292090 TP53INP2 0.65 5.75 0.46 6.61e-8 Coronary artery disease; TGCT cis rs7119 0.651 rs12902948 chr15:77849254 T/C cg27398640 chr15:77910606 LINGO1 -0.28 -5.2 -0.42 7.99e-7 Type 2 diabetes; TGCT cis rs2708977 0.842 rs10209780 chr2:97140142 T/G cg14837825 chr2:96917567 TMEM127 0.28 4.68 0.39 7.3e-6 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs259282 0.605 rs66489063 chr19:33108959 C/T cg26639809 chr19:33781782 NA 0.25 5.04 0.41 1.6e-6 Schizophrenia; TGCT cis rs1670533 1.000 rs6812586 chr4:1069851 A/G cg20887711 chr4:1340912 KIAA1530 0.69 5.5 0.44 2.03e-7 Recombination rate (females); TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs748404 0.660 rs693510 chr15:43714625 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs11148252 0.595 rs4884522 chr13:53053768 C/A cg00495681 chr13:53174319 NA 0.68 6.61 0.51 1e-9 Lewy body disease; TGCT cis rs425277 1.000 rs381664 chr1:2088104 A/G cg03732007 chr1:2071316 PRKCZ 0.26 5.52 0.44 1.89e-7 Height; TGCT cis rs7937682 0.632 rs2070894 chr11:111780837 G/A cg09085632 chr11:111637200 PPP2R1B 0.84 7.34 0.55 2.4e-11 Primary sclerosing cholangitis; TGCT cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs916888 0.610 rs199530 chr17:44836653 C/T cg01570182 chr17:44337453 NA -0.72 -6.93 -0.53 2.08e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs763014 0.932 rs2269560 chr16:682442 A/C cg00908189 chr16:619842 PIGQ 0.87 10.68 0.69 2.85e-19 Height; TGCT cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg12310025 chr6:25882481 NA -0.72 -6.54 -0.51 1.48e-9 Intelligence (multi-trait analysis); TGCT trans rs1496653 0.602 rs35383024 chr3:23492364 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs8103278 0.507 rs7246377 chr19:46292259 G/A cg14061069 chr19:46274453 DMPK 0.6 10.22 0.68 3.6e-18 Coronary artery disease; TGCT cis rs116095464 0.558 rs9688136 chr5:229348 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs9388451 0.626 rs1343115 chr6:126069817 C/G cg05901451 chr6:126070800 HEY2 -1.04 -13.0 -0.76 6.65e-25 Brugada syndrome; TGCT cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.48 0.61 5.53e-14 Platelet count; TGCT cis rs473651 0.904 rs62196716 chr2:239356977 C/G cg08773314 chr2:239334832 ASB1 0.44 7.37 0.55 2.13e-11 Multiple system atrophy; TGCT cis rs7666738 0.830 rs10014284 chr4:98681951 G/C cg05340658 chr4:99064831 C4orf37 0.46 5.42 0.44 3.01e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8103278 1.000 rs8102876 chr19:46332842 C/T cg14061069 chr19:46274453 DMPK -0.44 -6.14 -0.48 1.04e-8 Coronary artery disease; TGCT cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.67 4.75 0.39 5.62e-6 Platelet count; TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg11003573 chr3:44754125 ZNF502 -0.44 -5.15 -0.42 9.91e-7 Depressive symptoms; TGCT cis rs9733 0.628 rs72700895 chr1:150626029 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs7507204 0.530 rs4807469 chr19:3443382 G/C cg08380311 chr19:3435252 NFIC 1.17 15.97 0.82 7.09e-32 Height; TGCT cis rs17293817 0.625 rs10794748 chr10:1421516 A/G cg27336261 chr10:1975562 NA -0.31 -4.48 -0.37 1.66e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4455778 0.580 rs7783777 chr7:49082560 G/A cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs514406 0.505 rs448788 chr1:53161620 A/G cg22166914 chr1:53195759 ZYG11B -0.46 -7.85 -0.58 1.66e-12 Monocyte count; TGCT cis rs11792861 0.962 rs3750452 chr9:111801353 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.47 0.37 1.77e-5 Menarche (age at onset); TGCT cis rs16866061 0.888 rs6748341 chr2:225377574 C/G cg12698349 chr2:225449008 CUL3 0.98 9.06 0.63 2.32e-15 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs11190604 1.000 rs10883508 chr10:102294413 G/A cg23241863 chr10:102295624 HIF1AN 0.7 5.34 0.43 4.2e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7044106 0.762 rs1867254 chr9:123429078 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.63 6.68 0.51 7.09e-10 Hip circumference adjusted for BMI; TGCT cis rs6570726 0.755 rs2092296 chr6:145893684 A/C cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2251381 0.778 rs722013 chr21:30549245 G/T cg24692254 chr21:30365293 RNF160 0.74 7.29 0.55 3.15e-11 Selective IgA deficiency; TGCT cis rs2180341 0.538 rs11556354 chr6:127664661 G/A cg27446573 chr6:127587934 RNF146 0.64 5.87 0.47 3.71e-8 Breast cancer; TGCT cis rs921968 0.541 rs6710383 chr2:219359685 T/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs344364 0.529 rs186941 chr16:1930088 T/C cg26617929 chr16:1858877 NA 0.28 5.19 0.42 8.5e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs1865760 0.865 rs2164485 chr6:25952106 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT cis rs6121246 0.909 rs6058463 chr20:30385192 C/T cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs778371 0.697 rs11893358 chr2:233636922 T/C cg08000102 chr2:233561755 GIGYF2 0.72 8.56 0.61 3.68e-14 Schizophrenia; TGCT cis rs4563143 0.675 rs56123392 chr19:29255631 A/C cg14983838 chr19:29218262 NA 0.83 6.85 0.52 3.07e-10 Methadone dose in opioid dependence; TGCT cis rs950169 1.000 rs1818950 chr15:84722521 A/G cg11189052 chr15:85197271 WDR73 0.72 6.06 0.48 1.53e-8 Schizophrenia; TGCT cis rs6500602 0.702 rs3789038 chr16:4546586 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.31 -4.88 -0.4 3.26e-6 Schizophrenia; TGCT cis rs2370759 0.891 rs76164690 chr10:32590362 T/G cg01819863 chr10:32635814 EPC1 1.06 6.92 0.53 2.15e-10 Sexual dysfunction (female); TGCT cis rs7043114 0.507 rs10992340 chr9:95209693 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -5.35 -0.43 4.03e-7 Height; TGCT cis rs2836974 0.899 rs2836957 chr21:40623134 T/C cg11644478 chr21:40555479 PSMG1 1.0 10.69 0.69 2.7e-19 Cognitive function; TGCT cis rs2439831 0.702 rs9989313 chr15:44152817 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg13944838 chr5:179740914 GFPT2 0.4 6.42 0.5 2.65e-9 Height; TGCT cis rs12712073 0.845 rs6729966 chr2:100781566 A/G cg07810366 chr2:100720526 AFF3 -0.35 -5.26 -0.43 6e-7 Intelligence (multi-trait analysis); TGCT cis rs11122272 0.705 rs2491411 chr1:231533448 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.53 -0.51 1.55e-9 Hemoglobin concentration; TGCT cis rs72843506 0.722 rs16964352 chr17:20148408 A/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.89 -0.4 3.01e-6 Schizophrenia; TGCT cis rs694739 0.628 rs538147 chr11:64129722 G/A cg23796481 chr11:64053134 BAD;GPR137 0.6 6.02 0.48 1.81e-8 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9486715 0.867 rs1855533 chr6:97050265 T/C cg06623918 chr6:96969491 KIAA0776 -1.11 -15.34 -0.81 1.96e-30 Headache; TGCT cis rs950169 0.580 rs11630887 chr15:85193015 A/T cg17173187 chr15:85201210 NMB 0.59 6.7 0.52 6.63e-10 Schizophrenia; TGCT cis rs2014572 0.967 rs8111977 chr19:57759158 T/A cg24459738 chr19:57751996 ZNF805 -0.56 -5.6 -0.45 1.29e-7 Hyperactive-impulsive symptoms; TGCT trans rs208520 0.526 rs6913344 chr6:66754285 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.06 -14.91 -0.8 2e-29 Exhaled nitric oxide output; TGCT cis rs9325144 0.555 rs61929925 chr12:38698828 C/A cg26384229 chr12:38710491 ALG10B -0.65 -6.05 -0.48 1.62e-8 Morning vs. evening chronotype; TGCT cis rs9303401 0.659 rs61291849 chr17:56909867 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs3733585 0.805 rs882222 chr4:9981294 G/A cg00071950 chr4:10020882 SLC2A9 0.65 8.23 0.59 2.21e-13 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs2688608 0.901 rs2664282 chr10:75620757 T/C cg13918328 chr10:52500089 ASAH2B 0.67 6.92 0.53 2.19e-10 Inflammatory bowel disease; TGCT cis rs6089829 0.888 rs4809465 chr20:61671156 G/C cg08564027 chr20:61660810 NA 0.37 5.98 0.47 2.26e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs10972341 1.000 rs11521201 chr9:35158460 T/C cg00812861 chr9:35114699 KIAA1539 0.32 4.78 0.39 4.8e-6 Weight; TGCT cis rs9916302 0.706 rs667193 chr17:37448835 T/C cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs2153535 0.580 rs6905237 chr6:8471790 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.73 0.46 7.1e-8 Motion sickness; TGCT cis rs16957091 0.647 rs9920061 chr15:43234061 T/C cg17935677 chr15:44119062 WDR76 0.52 4.7 0.39 6.72e-6 MGMT methylation in smokers; TGCT trans rs525455 1.000 rs1659841 chr10:13102400 A/G cg21721093 chr17:8906386 NA 0.63 6.62 0.51 9.7e-10 Platelet aggregation; TGCT cis rs12048904 0.619 rs10875346 chr1:101328083 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.85 8.05 0.59 5.63e-13 Multiple sclerosis; TGCT cis rs7267979 0.934 rs2482913 chr20:25405086 T/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7312933 0.585 rs7969814 chr12:42669657 C/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.15 0.42 9.78e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7914558 1.000 rs2275271 chr10:104814162 T/C cg15744005 chr10:104629667 AS3MT -0.38 -4.69 -0.39 7.04e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4919669 0.668 rs4919666 chr10:104384029 G/A cg05855489 chr10:104503620 C10orf26 0.71 4.69 0.39 7.18e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs17125944 0.505 rs118053951 chr14:53259829 G/A cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs6570726 0.935 rs449377 chr6:145852437 C/G cg05347473 chr6:146136440 FBXO30 0.5 4.87 0.4 3.27e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6835098 0.692 rs6553680 chr4:174077044 A/G cg08422745 chr4:174089978 GALNT7 -0.77 -8.6 -0.61 2.87e-14 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs1801239 1.000 rs78786782 chr10:16937775 C/T cg00939682 chr10:16933505 CUBN 0.48 4.56 0.38 1.23e-5 Urinary albumin-to-creatinine ratio in non-diabetics;Urinary albumin excretion; TGCT cis rs523522 0.962 rs2233676 chr12:120933607 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg13393036 chr8:95962371 TP53INP1 -0.62 -8.39 -0.6 9.08e-14 Type 2 diabetes; TGCT cis rs6586163 0.843 rs1926199 chr10:90746660 G/T cg03111039 chr10:90751583 FAS;ACTA2 -0.38 -4.78 -0.39 4.79e-6 Chronic lymphocytic leukemia; TGCT cis rs36051895 0.589 rs62543574 chr9:5204090 A/T cg02405213 chr9:5042618 JAK2 -0.74 -9.28 -0.64 7.07e-16 Pediatric autoimmune diseases; TGCT cis rs7095607 1.000 rs7913582 chr10:69952581 T/C cg18986048 chr10:69913749 MYPN 0.46 4.93 0.41 2.54e-6 Lung function (FVC); TGCT cis rs2204008 0.805 rs11514348 chr12:38243427 T/C cg26384229 chr12:38710491 ALG10B 0.86 7.42 0.55 1.6e-11 Bladder cancer; TGCT cis rs9303401 0.659 rs62083436 chr17:57031742 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs11785400 1.000 rs10099892 chr8:143734608 C/T cg10596483 chr8:143751796 JRK 0.56 6.02 0.48 1.87e-8 Schizophrenia; TGCT cis rs4730430 0.538 rs10270301 chr7:110133558 C/T cg14239618 chr7:110281356 NA 0.25 4.7 0.39 6.67e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2282802 0.617 rs10477348 chr5:139666906 A/T cg01081189 chr5:139537190 NA 0.28 5.01 0.41 1.84e-6 Intelligence (multi-trait analysis); TGCT cis rs7819412 0.669 rs28630509 chr8:10997039 A/G cg21775007 chr8:11205619 TDH -0.55 -5.05 -0.41 1.53e-6 Triglycerides; TGCT cis rs9894429 1.000 rs12948099 chr17:79600799 C/G cg18240062 chr17:79603768 NPLOC4 0.7 7.16 0.54 6.24e-11 Eye color traits; TGCT cis rs6988636 1.000 rs28513831 chr8:124189208 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9486715 0.867 rs4839828 chr6:96863326 G/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs694419 0.602 rs1473980 chr18:60206676 C/T cg13506219 chr18:60193840 ZCCHC2 0.53 4.74 0.39 5.77e-6 Serum albumin level; TGCT cis rs1903068 0.719 rs1380068 chr4:56003707 C/G cg09978860 chr4:56023921 NA 0.54 5.76 0.46 6.3e-8 Endometriosis; TGCT cis rs875971 0.522 rs4502988 chr7:65297746 A/G cg18876405 chr7:65276391 NA 0.35 5.66 0.45 1.01e-7 Aortic root size; TGCT cis rs7044106 0.791 rs10984994 chr9:123478769 A/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.42 -4.49 -0.37 1.59e-5 Hip circumference adjusted for BMI; TGCT cis rs921968 0.612 rs2384950 chr2:219499719 T/C cg02176678 chr2:219576539 TTLL4 0.43 6.13 0.48 1.06e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg17178900 chr1:205818956 PM20D1 0.59 7.49 0.56 1.14e-11 Menarche (age at onset); TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs4727027 0.870 rs62507509 chr7:148795522 C/T cg23583168 chr7:148888333 NA -0.72 -9.11 -0.63 1.8e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.99 0.47 2.06e-8 Bipolar disorder; TGCT cis rs1347297 0.526 rs728005 chr2:179251006 C/T cg03991736 chr2:179345203 MIR548N;PLEKHA3 -0.51 -4.83 -0.4 3.88e-6 Alzheimer disease and age of onset; TGCT cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg25151919 chr3:44754333 ZNF502 -0.47 -5.45 -0.44 2.56e-7 Depressive symptoms; TGCT cis rs11252926 0.563 rs10795103 chr10:451849 C/A cg20256804 chr10:444983 DIP2C -0.22 -4.68 -0.39 7.34e-6 Psychosis in Alzheimer's disease; TGCT cis rs7027203 1.000 rs7864114 chr9:96551954 A/G cg13679303 chr9:96623674 NA 0.65 9.81 0.66 3.61e-17 DNA methylation (variation); TGCT cis rs11690462 0.963 rs4007242 chr2:26596915 C/T cg04726446 chr2:26624865 C2orf39 0.43 4.64 0.38 8.58e-6 Coronary artery disease; TGCT trans rs6089829 0.962 rs2314130 chr20:61665129 G/T cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs74054849 0.717 rs1547032 chr1:15918974 G/A cg05660106 chr1:15850417 CASP9 0.93 4.76 0.39 5.39e-6 Alcoholic chronic pancreatitis; TGCT trans rs3780486 0.505 rs10758194 chr9:33157419 G/T cg20290983 chr6:43655470 MRPS18A 0.77 8.36 0.6 1.07e-13 IgG glycosylation; TGCT cis rs11105298 0.891 rs10858854 chr12:89835728 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1729951 0.575 rs1682333 chr3:136688618 G/A cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs59107033 0.607 rs62262407 chr3:123122637 T/A cg04890266 chr3:123102914 ADCY5 -0.38 -5.62 -0.45 1.18e-7 Lymphocyte counts; TGCT cis rs3782455 0.793 rs77046876 chr12:114404271 G/A cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7267979 1.000 rs6083825 chr20:25366424 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12477438 0.520 rs13030961 chr2:99799520 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.32 0.85 4.52e-37 Chronic sinus infection; TGCT cis rs2204008 0.744 rs11514073 chr12:38399553 A/C cg13010199 chr12:38710504 ALG10B 0.61 4.82 0.4 4.12e-6 Bladder cancer; TGCT cis rs7824557 0.606 rs1435277 chr8:11196970 C/T cg21775007 chr8:11205619 TDH 0.74 6.99 0.53 1.49e-10 Retinal vascular caliber; TGCT cis rs9926296 0.572 rs8046872 chr16:89841552 T/C cg27121462 chr16:89883253 FANCA 0.57 5.3 0.43 5.03e-7 Vitiligo; TGCT cis rs60154123 0.505 rs76426571 chr1:210041634 C/T cg04352962 chr1:209979756 IRF6 0.69 4.73 0.39 6.04e-6 Coronary artery disease; TGCT cis rs7296418 0.663 rs11057276 chr12:123820397 C/T cg00376283 chr12:123451042 ABCB9 -0.63 -5.42 -0.44 3.02e-7 Platelet count; TGCT cis rs1990950 0.692 rs1157344 chr5:156836438 A/G cg25387487 chr5:157003181 ADAM19 0.29 4.47 0.37 1.73e-5 Lung function (FEV1/FVC); TGCT cis rs6570726 0.791 rs2096201 chr6:145934273 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.69 0.66 7.3e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs17173637 0.510 rs73165509 chr7:150522870 G/C cg09499965 chr7:151220664 NA 0.3 4.46 0.37 1.84e-5 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7178572 0.568 rs1389436 chr15:77665848 G/T cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.58e-6 Type 2 diabetes; TGCT cis rs11785400 0.793 rs7000765 chr8:143722457 G/A cg10596483 chr8:143751796 JRK 0.54 5.25 0.43 6.48e-7 Schizophrenia; TGCT cis rs9486719 1.000 rs2472889 chr6:96866803 T/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7681440 0.835 rs7668531 chr4:90791819 G/T cg26578617 chr4:90757533 SNCA -0.45 -4.63 -0.38 9.09e-6 Dementia with Lewy bodies; TGCT cis rs8072100 0.967 rs62076549 chr17:45579555 T/G cg08085267 chr17:45401833 C17orf57 0.44 4.63 0.38 8.96e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs597539 0.690 rs497149 chr11:68626639 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 7.76 0.57 2.67e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs28595532 0.920 rs116047800 chr4:119773569 G/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs4319547 0.688 rs10847415 chr12:123144293 T/C cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.83 -0.4 4.03e-6 Body mass index; TGCT cis rs10840270 0.638 rs10770047 chr11:9630969 C/G cg03787988 chr11:10602522 MRVI1 -0.2 -4.59 -0.38 1.09e-5 Bacteremia; TGCT trans rs1814175 0.616 rs1794131 chr11:49904194 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs4242434 0.854 rs13258100 chr8:22451116 A/T cg03733263 chr8:22462867 KIAA1967 1.09 17.25 0.84 9.34e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9399135 0.967 rs4388304 chr6:135309597 T/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg10047753 chr17:41438598 NA 0.97 9.87 0.66 2.55e-17 Menopause (age at onset); TGCT cis rs6490294 0.800 rs78783055 chr12:112233495 G/A cg10833066 chr12:111807467 FAM109A 0.37 4.72 0.39 6.22e-6 Mean platelet volume; TGCT cis rs826838 0.834 rs826874 chr12:39122599 C/A cg13010199 chr12:38710504 ALG10B -0.62 -4.94 -0.41 2.49e-6 Heart rate; TGCT cis rs4746818 1.000 rs7916991 chr10:70895373 C/A cg11621586 chr10:70884670 VPS26A 1.13 8.03 0.58 6.56e-13 Left atrial antero-posterior diameter; TGCT cis rs9486719 0.947 rs12213375 chr6:96902134 A/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs3935685 0.874 rs4477663 chr15:78007254 A/G cg25212270 chr15:78015279 NA -0.25 -5.48 -0.44 2.32e-7 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.865 rs9467652 chr6:25959127 A/G cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs7312933 0.702 rs10785333 chr12:42586470 A/G cg19980929 chr12:42632907 YAF2 -0.47 -6.46 -0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1044826 0.692 rs188420 chr3:139233865 G/A cg00490450 chr3:139108681 COPB2 -0.51 -4.48 -0.37 1.67e-5 Obesity-related traits; TGCT cis rs7914558 0.966 rs11191471 chr10:104702050 T/A cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9611565 0.694 rs5758368 chr22:41862288 C/T cg06481639 chr22:41940642 POLR3H -0.71 -6.4 -0.5 2.93e-9 Vitiligo; TGCT cis rs11190604 0.767 rs11190533 chr10:102190792 T/C cg16342193 chr10:102329863 NA -0.38 -5.0 -0.41 1.93e-6 Palmitoleic acid (16:1n-7) levels; TGCT trans rs1814175 0.817 rs12290508 chr11:49621037 C/T cg03929089 chr4:120376271 NA -0.74 -8.94 -0.63 4.54e-15 Height; TGCT cis rs4595586 0.545 rs7972590 chr12:39376615 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs875971 1.000 rs6945843 chr7:65734783 G/A cg11764359 chr7:65958608 NA -0.61 -5.39 -0.44 3.45e-7 Aortic root size; TGCT cis rs644799 1.000 rs7749 chr11:95565789 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 7.92 0.58 1.12e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg09177884 chr7:1199841 ZFAND2A -0.52 -4.98 -0.41 2.04e-6 Longevity;Endometriosis; TGCT trans rs1005277 0.579 rs1780116 chr10:38526621 C/T cg27523141 chr10:43048294 ZNF37B 0.73 8.5 0.61 5.09e-14 Extrinsic epigenetic age acceleration; TGCT trans rs10506458 1.000 rs73127086 chr12:63415626 G/A cg22491629 chr6:157744540 C6orf35 -0.99 -8.57 -0.61 3.45e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs9677476 0.516 rs59886388 chr2:231995770 G/C cg07929768 chr2:232055508 NA 0.34 5.26 0.43 6.11e-7 Food antigen IgG levels; TGCT cis rs10782582 0.593 rs11163904 chr1:76121208 A/G cg10523679 chr1:76189770 ACADM 0.69 7.44 0.56 1.5e-11 Daytime sleep phenotypes; TGCT cis rs9399137 0.507 rs7771310 chr6:135272535 G/A cg24558204 chr6:135376177 HBS1L 0.49 4.94 0.41 2.49e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg05665937 chr4:1216051 CTBP1 0.26 5.05 0.41 1.54e-6 Obesity-related traits; TGCT cis rs595982 0.527 rs35087747 chr19:49377918 G/T cg21252483 chr19:49399788 TULP2 -0.48 -7.32 -0.55 2.8e-11 Red cell distribution width; TGCT cis rs734999 0.545 rs4648356 chr1:2709164 C/A cg18854424 chr1:2615690 NA 0.45 4.99 0.41 1.99e-6 Ulcerative colitis; TGCT cis rs2153535 0.546 rs1335640 chr6:8485325 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10193935 0.901 rs12615383 chr2:42610551 A/G cg27598129 chr2:42591480 NA 0.41 5.66 0.45 1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10779751 0.734 rs2791650 chr1:11132541 G/C cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs28595532 0.920 rs114162429 chr4:119741078 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs13256369 1.000 rs13267501 chr8:8574058 G/A cg17143192 chr8:8559678 CLDN23 0.63 5.93 0.47 2.8e-8 Obesity-related traits; TGCT trans rs1864729 1.000 rs2028479 chr8:98290772 T/G cg08679828 chr8:102218111 ZNF706 -1.03 -7.21 -0.54 4.94e-11 Estradiol plasma levels (breast cancer); TGCT cis rs12908161 0.959 rs1051168 chr15:85200520 G/T cg17173187 chr15:85201210 NMB 0.6 6.74 0.52 5.39e-10 Schizophrenia; TGCT cis rs10488031 0.557 rs34870838 chr7:37108148 C/T cg06458904 chr7:36312573 EEPD1 0.58 4.79 0.39 4.72e-6 QT interval; TGCT cis rs7833790 0.654 rs7835342 chr8:82698092 A/G cg06027949 chr8:82754900 SNX16 -0.6 -4.69 -0.39 7.14e-6 Diastolic blood pressure; TGCT cis rs7611238 0.560 rs9870236 chr3:195129741 G/A cg27323046 chr3:195102265 ACAP2 0.38 5.04 0.41 1.57e-6 Body mass index; TGCT cis rs780096 0.546 rs2911712 chr2:27626945 A/T cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.46 -0.37 1.84e-5 Total body bone mineral density; TGCT cis rs16939607 1.000 rs62510269 chr8:79012343 A/G cg21244580 chr8:79934476 NA 0.47 4.68 0.39 7.33e-6 White blood cell count; TGCT cis rs7552404 1.000 rs4949876 chr1:76173377 C/T cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs709400 0.663 rs11628969 chr14:103940911 G/A cg12935359 chr14:103987150 CKB -0.36 -5.55 -0.45 1.67e-7 Body mass index; TGCT cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg13683864 chr3:40499215 RPL14 -1.1 -11.83 -0.73 4.49e-22 Renal cell carcinoma; TGCT cis rs3091242 0.933 rs28633797 chr1:25741629 C/A cg23205692 chr1:25664452 TMEM50A 0.52 5.38 0.43 3.59e-7 Erythrocyte sedimentation rate; TGCT cis rs10984561 0.881 rs58554876 chr9:122219555 C/G cg14242995 chr9:122249943 NA 0.69 5.74 0.46 6.79e-8 Pulmonary function decline; TGCT cis rs9611565 0.512 rs45500192 chr22:42177899 A/G cg17554472 chr22:41940697 POLR3H -0.46 -4.79 -0.39 4.71e-6 Vitiligo; TGCT cis rs17376456 0.877 rs12374463 chr5:93483569 C/G cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.21e-14 Diabetic retinopathy; TGCT cis rs9443645 0.901 rs7767100 chr6:79810533 A/C cg09184832 chr6:79620586 NA -0.47 -5.07 -0.41 1.4e-6 Intelligence (multi-trait analysis); TGCT cis rs185694 0.779 rs653221 chr13:30894567 G/C cg07600127 chr13:30881527 KATNAL1 -0.76 -6.27 -0.49 5.4e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs11690935 0.632 rs35854151 chr2:172657439 G/A cg13550731 chr2:172543902 DYNC1I2 0.69 6.04 0.48 1.69e-8 Schizophrenia; TGCT cis rs909674 0.818 rs5750830 chr22:39840828 C/A cg11247378 chr22:39784982 NA -0.72 -8.54 -0.61 4.11e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs12286929 0.637 rs3802858 chr11:115078492 T/C cg16269184 chr11:114127960 NA 0.2 4.49 0.37 1.59e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs453301 0.686 rs13252797 chr8:8861430 A/G cg15556689 chr8:8085844 FLJ10661 0.61 4.89 0.4 3.04e-6 Joint mobility (Beighton score); TGCT cis rs2721195 0.781 rs10110962 chr8:145780323 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.91 10.04 0.67 9.97e-18 Age at first birth; TGCT cis rs17076896 0.786 rs61956084 chr13:19936305 C/T cg00777926 chr13:20807375 GJB6 -0.41 -4.82 -0.4 4.03e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg09436375 chr6:42928200 GNMT -0.4 -5.23 -0.42 7.13e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9611565 0.694 rs11090056 chr22:42095904 A/C cg13695892 chr22:41940480 POLR3H 0.84 8.04 0.59 5.93e-13 Vitiligo; TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg24675658 chr1:53192096 ZYG11B -0.71 -8.23 -0.59 2.14e-13 Monocyte count; TGCT cis rs988712 0.705 rs4923460 chr11:27656789 A/C cg10635145 chr11:27742435 BDNF 0.37 5.02 0.41 1.79e-6 Obesity; TGCT cis rs9467773 1.000 rs6932156 chr6:26571506 T/G cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs11264213 0.901 rs665521 chr1:36445837 T/C cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs4285028 0.948 rs1920290 chr3:121672305 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs3845702 0.736 rs6722147 chr2:180829704 G/A cg01881094 chr2:180872142 CWC22 -1.03 -6.51 -0.5 1.72e-9 Schizophrenia; TGCT cis rs7843479 0.562 rs11774629 chr8:21859315 C/T cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.11e-12 Mean corpuscular volume; TGCT cis rs1008375 0.863 rs4698632 chr4:17614894 T/C cg10189774 chr4:17578691 LAP3 0.57 4.85 0.4 3.56e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9790314 0.871 rs339114 chr3:161109220 C/T cg03342759 chr3:160939853 NMD3 0.47 5.04 0.41 1.6e-6 Morning vs. evening chronotype; TGCT cis rs597539 0.654 rs655816 chr11:68626405 A/G cg21862992 chr11:68658383 NA 0.47 6.45 0.5 2.29e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6815814 0.950 rs5743563 chr4:38806019 A/G cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs9311474 1.000 rs9311474 chr3:52338852 T/C cg10802521 chr3:52805072 NEK4 -0.59 -6.4 -0.5 2.91e-9 Electroencephalogram traits; TGCT cis rs903263 1.000 rs10874432 chr1:84673951 T/C cg09664975 chr1:84543551 PRKACB 0.48 4.57 0.38 1.16e-5 Breast cancer (male); TGCT cis rs344364 0.511 rs911392 chr16:1947259 A/G cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs8078723 0.701 rs2305482 chr17:38140927 A/C cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7714584 1.000 rs61530785 chr5:150261364 A/G cg22134413 chr5:150180641 NA 1.09 7.73 0.57 3.18e-12 Crohn's disease; TGCT cis rs12368653 0.616 rs1027315 chr12:58034192 T/C cg12615879 chr12:58013172 SLC26A10 0.51 6.25 0.49 6.12e-9 Multiple sclerosis; TGCT cis rs1401999 1.000 rs4148575 chr3:183702275 A/G cg01324343 chr3:183735012 ABCC5 0.82 10.56 0.69 5.39e-19 Anterior chamber depth; TGCT cis rs4711350 1.000 rs2182659 chr6:33751767 A/G cg18005901 chr6:33739558 LEMD2 -0.55 -5.89 -0.47 3.39e-8 Schizophrenia; TGCT cis rs9788682 0.747 rs8042494 chr15:78908010 C/T cg24631222 chr15:78858424 CHRNA5 0.83 6.21 0.49 7.37e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9549367 0.756 rs2316463 chr13:113901406 C/T cg00898013 chr13:113819073 PROZ -0.41 -5.06 -0.41 1.46e-6 Platelet distribution width; TGCT cis rs77741769 0.529 rs2047568 chr12:121243790 A/G cg25946681 chr12:120654588 PXN 0.19 4.45 0.37 1.85e-5 Mean corpuscular volume; TGCT cis rs2066819 1.000 rs76745316 chr12:56627652 A/C cg26714650 chr12:56694279 CS -1.42 -5.7 -0.46 8.43e-8 Psoriasis vulgaris; TGCT cis rs3733585 0.673 rs4455410 chr4:9953297 C/T cg11266682 chr4:10021025 SLC2A9 0.55 7.36 0.55 2.27e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs782590 0.902 rs782602 chr2:55849309 A/G cg03859395 chr2:55845619 SMEK2 0.87 10.47 0.68 9.16e-19 Metabolic syndrome; TGCT cis rs9549367 0.789 rs12869947 chr13:113896156 A/G cg00898013 chr13:113819073 PROZ -0.41 -5.11 -0.42 1.17e-6 Platelet distribution width; TGCT cis rs9733 0.596 rs72702557 chr1:150680130 A/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.52 5.49 0.44 2.14e-7 Menopause (age at onset); TGCT trans rs877282 0.853 rs12779017 chr10:763619 T/C cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs7727544 0.654 rs4705849 chr5:131559199 T/A cg24060327 chr5:131705240 SLC22A5 -0.54 -5.1 -0.42 1.23e-6 Blood metabolite levels; TGCT cis rs1541995 1.000 rs34636500 chr15:96353983 T/A cg00882281 chr15:96346592 NA 0.29 4.76 0.39 5.31e-6 Photic sneeze reflex; TGCT cis rs6978712 1.000 rs79045902 chr7:127147127 A/G cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.57 -0.38 1.14e-5 Obesity-related traits; TGCT trans rs1005277 0.579 rs2504140 chr10:38387579 T/G cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs17221829 0.703 rs7944552 chr11:89377208 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs925228 0.504 rs7568176 chr2:24313758 T/A cg01493198 chr2:24299560 SF3B14 0.73 4.75 0.39 5.43e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs7552404 1.000 rs7518038 chr1:76154430 G/A cg22875332 chr1:76189707 ACADM 0.79 9.71 0.66 6.51e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 6.72 0.52 5.79e-10 Schizophrenia; TGCT cis rs2243480 1.000 rs7778911 chr7:65694506 T/C cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs965469 0.895 rs6051844 chr20:3402674 G/T cg14326260 chr20:3913389 RNF24 0.29 4.54 0.38 1.32e-5 IFN-related cytopenia; TGCT cis rs1865760 0.929 rs2876693 chr6:25954434 C/G cg16482183 chr6:26056742 HIST1H1C 0.5 4.45 0.37 1.9e-5 Height; TGCT cis rs11153730 0.503 rs283066 chr6:118620064 A/G cg21191810 chr6:118973309 C6orf204 0.27 4.53 0.38 1.36e-5 QT interval;Heart rate;QRS duration;QRS complex (Sokolow-Lyon); TGCT cis rs4319547 0.695 rs55834409 chr12:122862560 C/G cg05707623 chr12:122985044 ZCCHC8 0.62 4.87 0.4 3.32e-6 Body mass index; TGCT cis rs10992471 0.603 rs12341817 chr9:95252152 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.47 -0.44 2.4e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg01084871 chr4:1340883 KIAA1530 0.66 5.02 0.41 1.73e-6 Longevity; TGCT cis rs41271473 0.526 rs72765760 chr1:228743222 G/A cg16512390 chr1:228756714 NA 0.72 4.46 0.37 1.85e-5 Chronic lymphocytic leukemia; TGCT cis rs1552244 0.882 rs55808392 chr3:10054681 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs2637266 0.703 rs11001861 chr10:78473552 A/C cg18941641 chr10:78392320 NA 0.4 4.8 0.4 4.52e-6 Pulmonary function; TGCT cis rs12220898 0.749 rs3996894 chr10:50484369 G/A cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs41271473 0.519 rs9660783 chr1:228886880 C/T cg10167378 chr1:228756711 NA 0.56 4.65 0.39 8.27e-6 Chronic lymphocytic leukemia; TGCT cis rs17345786 0.906 rs58835747 chr3:101243634 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.85 8.64 0.61 2.38e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg03188948 chr7:1209495 NA 0.42 5.52 0.44 1.89e-7 Longevity;Endometriosis; TGCT cis rs6088590 0.648 rs6058105 chr20:33271719 C/T cg08999081 chr20:33150536 PIGU 0.24 4.63 0.38 9.14e-6 Coronary artery disease; TGCT cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg02458000 chr6:26745757 NA 0.55 5.29 0.43 5.31e-7 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.967 rs6924865 chr6:26521353 A/G cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs71435601 0.628 rs312970 chr2:21369815 A/T cg25035485 chr2:21266500 APOB 0.49 4.45 0.37 1.92e-5 Cholesterol, total; TGCT cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg20203395 chr5:56204925 C5orf35 -0.57 -5.03 -0.41 1.69e-6 Initial pursuit acceleration; TGCT cis rs250677 0.522 rs891920 chr5:148369418 G/T cg18129178 chr5:148520854 ABLIM3 -0.36 -4.69 -0.39 7.23e-6 Breast cancer; TGCT cis rs10782582 0.609 rs5745543 chr1:76365111 A/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.48 0.37 1.66e-5 Daytime sleep phenotypes; TGCT cis rs2836974 0.897 rs1984022 chr21:40596085 G/A cg11890956 chr21:40555474 PSMG1 1.1 12.31 0.74 2.99e-23 Cognitive function; TGCT cis rs9393777 0.513 rs7740197 chr6:26663478 C/T cg06675483 chr6:26987649 LOC100270746;C6orf41 0.51 4.76 0.39 5.25e-6 Intelligence (multi-trait analysis); TGCT cis rs2742417 1.000 rs2742389 chr3:45756683 G/C cg04837898 chr3:45731254 SACM1L -0.52 -5.28 -0.43 5.58e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs17376456 0.825 rs10476590 chr5:93244884 A/T cg09848695 chr5:92956644 FAM172A;MIR2277 0.74 4.89 0.4 3.12e-6 Diabetic retinopathy; TGCT cis rs9303401 0.659 rs8074016 chr17:56840587 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs73198271 0.843 rs11775888 chr8:8605698 G/C ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.73 -0.39 5.95e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs4455778 0.538 rs6583514 chr7:49123556 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs3858526 0.508 rs10838734 chr11:5876325 T/G cg05234568 chr11:5960015 NA -0.47 -4.62 -0.38 9.49e-6 DNA methylation (variation); TGCT cis rs6089584 0.888 rs6061983 chr20:60621202 T/C cg13665807 chr20:60559372 TAF4 -0.46 -4.9 -0.4 2.87e-6 Body mass index; TGCT cis rs3096299 0.679 rs3096322 chr16:89441123 A/G cg06640241 chr16:89574553 SPG7 -0.63 -5.69 -0.46 8.46e-8 Multiple myeloma (IgH translocation); TGCT cis rs68170813 0.652 rs6958969 chr7:107197755 A/T cg02696742 chr7:106810147 HBP1 -0.59 -4.71 -0.39 6.61e-6 Coronary artery disease; TGCT cis rs7605378 0.528 rs1704191 chr2:200816393 C/A cg23649088 chr2:200775458 C2orf69 0.47 10.04 0.67 9.98e-18 Osteoporosis; TGCT cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs7552404 0.727 rs7547056 chr1:76279267 C/T cg22875332 chr1:76189707 ACADM 0.64 6.9 0.53 2.32e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3125734 0.633 rs4979772 chr10:63967600 C/T cg19640130 chr10:64028056 RTKN2 0.41 5.33 0.43 4.54e-7 Rheumatoid arthritis; TGCT cis rs425277 0.565 rs61775448 chr1:2045376 A/G cg03732007 chr1:2071316 PRKCZ -0.24 -5.38 -0.44 3.57e-7 Height; TGCT cis rs2382817 0.580 rs6756265 chr2:219095554 G/A cg00012203 chr2:219082015 ARPC2 -0.81 -9.41 -0.65 3.47e-16 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; TGCT cis rs11578119 0.898 rs4363474 chr1:170382898 T/C cg09767346 chr1:170501363 GORAB -0.72 -5.72 -0.46 7.52e-8 Male-pattern baldness; TGCT cis rs8141529 0.778 rs763073 chr22:29215542 G/A cg02153584 chr22:29168773 CCDC117 0.62 5.52 0.44 1.92e-7 Lymphocyte counts; TGCT cis rs12291225 0.585 rs11023194 chr11:14369769 T/C cg19336497 chr11:14380999 RRAS2 -0.45 -7.26 -0.55 3.67e-11 Sense of smell; TGCT cis rs1005277 0.505 rs7069702 chr10:38247359 G/T cg25427524 chr10:38739819 LOC399744 0.38 7.67 0.57 4.25e-12 Extrinsic epigenetic age acceleration; TGCT cis rs11148252 0.508 rs6561671 chr13:53182314 G/A cg00495681 chr13:53174319 NA 0.6 5.91 0.47 3.06e-8 Lewy body disease; TGCT cis rs1682825 0.858 rs6795031 chr3:10763012 C/T cg23512531 chr3:10780469 NA -0.64 -4.85 -0.4 3.67e-6 Economic and political preferences (feminism/equality); TGCT cis rs4819052 1.000 rs2297284 chr21:46705345 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.73 5.09 0.42 1.28e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3087591 0.690 rs12103621 chr17:29607235 T/A cg24425628 chr17:29625626 OMG;NF1 -0.45 -6.52 -0.51 1.62e-9 Hip circumference; TGCT cis rs2277425 0.755 rs2277424 chr13:111522420 A/G cg04513422 chr13:111522314 C13orf29 -0.56 -7.43 -0.56 1.52e-11 Sitting height ratio; TGCT cis rs2880765 0.835 rs7174323 chr15:86049719 A/C cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs524023 1.000 rs10792441 chr11:64360629 C/T cg07733098 chr11:64478343 NRXN2 0.31 4.66 0.39 8.01e-6 Urate levels in obese individuals; TGCT cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg21724239 chr8:58056113 NA 0.41 4.87 0.4 3.33e-6 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.586 rs2866862 chr11:49954588 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg23156509 chr2:114033830 PAX8;LOC440839 -0.31 -4.83 -0.4 3.92e-6 Lymphocyte counts; TGCT cis rs4727027 0.754 rs917124 chr7:148851213 C/T cg23583168 chr7:148888333 NA -0.69 -7.8 -0.57 2.21e-12 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9787249 0.957 rs12074147 chr1:40203722 T/C cg19912559 chr1:40204330 PPIE 0.47 5.42 0.44 2.96e-7 Blood protein levels; TGCT cis rs1865760 0.566 rs9358904 chr6:26068566 C/T cg17042849 chr6:26104293 HIST1H4C -0.61 -5.21 -0.42 7.74e-7 Height; TGCT cis rs10754283 0.967 rs10801763 chr1:90120822 C/T cg03145924 chr1:90228473 NA -0.4 -4.52 -0.38 1.4e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs41271951 0.512 rs77306500 chr1:151080096 G/C cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs1801251 1.000 rs6747645 chr2:233571033 C/T cg25237894 chr2:233734115 C2orf82 -0.29 -5.23 -0.42 7.13e-7 Coronary artery disease; TGCT cis rs2730260 0.537 rs3793223 chr7:158863574 C/A cg02078164 chr7:157982224 PTPRN2 0.42 4.67 0.39 7.79e-6 Myopia (pathological); TGCT cis rs7172809 0.573 rs58792939 chr15:77548113 C/G cg22256960 chr15:77711686 NA -0.48 -4.67 -0.39 7.76e-6 Glucose homeostasis traits; TGCT cis rs72781680 0.799 rs2712084 chr2:24003051 A/G cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs6987853 0.814 rs2923415 chr8:42455577 A/G cg20539142 chr8:42623718 CHRNA6 -0.2 -5.03 -0.41 1.7e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs6840360 0.615 rs12641438 chr4:152607586 A/G cg22705602 chr4:152727874 NA -0.32 -5.41 -0.44 3.12e-7 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs55668908 chr4:119769799 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs921968 0.643 rs590771 chr2:219369851 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs113577745 0.623 rs73913932 chr2:10094526 A/G cg17603321 chr2:9696605 ADAM17 -1.08 -4.74 -0.39 5.79e-6 Breast cancer; TGCT cis rs151997 1.000 rs152690 chr5:50213584 A/T cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs36051895 0.664 rs10974963 chr9:5101305 G/A cg02405213 chr9:5042618 JAK2 -0.71 -9.43 -0.65 3.07e-16 Pediatric autoimmune diseases; TGCT cis rs9611565 0.569 rs6002328 chr22:41710034 T/C cg06634786 chr22:41940651 POLR3H -0.58 -5.28 -0.43 5.62e-7 Vitiligo; TGCT cis rs733175 0.857 rs10018663 chr4:10004797 C/T cg11266682 chr4:10021025 SLC2A9 0.52 4.5 0.37 1.55e-5 Psychosis and Alzheimer's disease; TGCT cis rs9921338 0.923 rs6498181 chr16:11427193 C/T cg00044050 chr16:11439710 C16orf75 -0.91 -7.07 -0.54 1.01e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4987668 0.786 rs4252383 chr7:142629241 T/C cg21621906 chr7:142494914 NA -0.9 -4.62 -0.38 9.48e-6 Cancer; TGCT cis rs13096760 1 rs13096760 chr3:49476806 T/C cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Intelligence (multi-trait analysis); TGCT cis rs12549902 0.966 rs12544241 chr8:41514888 G/A cg00088007 chr8:41504566 NKX6-3 0.34 5.31 0.43 4.93e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.58 -5.34 -0.43 4.21e-7 Prudent dietary pattern; TGCT cis rs17345786 1.000 rs3762729 chr3:101308874 C/T cg11279151 chr3:101281821 RG9MTD1 -0.45 -9.65 -0.65 8.81e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs7246657 0.524 rs28542490 chr19:37456584 C/A cg18154014 chr19:37997991 ZNF793 0.73 4.6 0.38 1.04e-5 Coronary artery calcification; TGCT trans rs1496653 0.602 rs34894979 chr3:23475386 G/A cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg13770153 chr20:60521292 NA -0.62 -7.94 -0.58 1.02e-12 Body mass index; TGCT cis rs1865760 0.623 rs12216125 chr6:25997458 C/T cg17691542 chr6:26056736 HIST1H1C 0.64 5.25 0.43 6.45e-7 Height; TGCT cis rs2996428 0.667 rs2368534 chr1:3740640 C/T cg17848003 chr1:3704513 LRRC47 0.19 5.01 0.41 1.82e-6 Red cell distribution width; TGCT cis rs2243480 1.000 rs2462569 chr7:65474846 C/T cg18252515 chr7:66147081 NA 1.31 8.18 0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs2243480 0.522 rs73150635 chr7:65972490 C/T cg18252515 chr7:66147081 NA -1.08 -6.3 -0.49 4.68e-9 Diabetic kidney disease; TGCT cis rs2235642 0.928 rs56289115 chr16:1608934 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.3 -5.34 -0.43 4.26e-7 Coronary artery disease; TGCT cis rs4819052 0.851 rs2838856 chr21:46680766 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 6.53 0.51 1.54e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2013441 1.000 rs2263175 chr17:20128029 C/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs9393692 0.905 rs1125000 chr6:26287256 C/T cg05868516 chr6:26286170 HIST1H4H 0.61 5.84 0.46 4.31e-8 Educational attainment; TGCT cis rs28595532 0.920 rs114940990 chr4:119758568 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs9653442 0.545 rs12987212 chr2:100761156 C/T cg22139774 chr2:100720529 AFF3 -0.36 -5.72 -0.46 7.68e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1801251 0.929 rs12694917 chr2:233707611 C/T cg25237894 chr2:233734115 C2orf82 -0.31 -5.44 -0.44 2.75e-7 Coronary artery disease; TGCT cis rs1401999 0.690 rs6768149 chr3:183636195 T/C cg01324343 chr3:183735012 ABCC5 0.69 8.13 0.59 3.77e-13 Anterior chamber depth; TGCT cis rs873946 0.590 rs12259699 chr10:134549692 A/G cg18305652 chr10:134549665 INPP5A 0.31 4.93 0.4 2.61e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6993244 1 rs6993244 chr8:8863059 C/G cg06636001 chr8:8085503 FLJ10661 0.78 6.97 0.53 1.62e-10 Mean corpuscular hemoglobin; TGCT trans rs941408 1.000 rs1640273 chr19:2803227 C/T cg19676328 chr12:49525230 TUBA1B -0.7 -6.66 -0.51 8.07e-10 Total cholesterol levels; TGCT cis rs4642101 0.662 rs9874893 chr3:12833079 C/G cg05775895 chr3:12838266 CAND2 0.89 9.71 0.66 6.47e-17 QRS complex (12-leadsum); TGCT cis rs9926296 0.546 rs7187436 chr16:89845110 A/T cg21285383 chr16:89894308 SPIRE2 0.48 7.49 0.56 1.12e-11 Vitiligo; TGCT cis rs7772486 0.754 rs864148 chr6:145976675 T/C cg05347473 chr6:146136440 FBXO30 -0.52 -4.85 -0.4 3.62e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6882046 0.513 rs587490 chr5:88032522 C/T cg24804195 chr5:87968844 LOC645323 -0.59 -5.9 -0.47 3.31e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs1129187 0.967 rs6941212 chr6:42915920 A/G cg27588902 chr6:42928151 GNMT -0.4 -4.99 -0.41 1.99e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7666738 0.830 rs13138920 chr4:99020786 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs56334439 0.764 rs9852879 chr3:60098201 A/C cg17894779 chr3:60066405 FHIT -0.35 -4.81 -0.4 4.3e-6 Myringotomy; TGCT cis rs986417 0.901 rs1884098 chr14:61038944 A/T cg27398547 chr14:60952738 C14orf39 1.48 10.7 0.69 2.57e-19 Gut microbiota (bacterial taxa); TGCT cis rs2933343 0.729 rs813732 chr3:128619357 C/T cg11901034 chr3:128598214 ACAD9 -0.66 -6.56 -0.51 1.33e-9 IgG glycosylation; TGCT cis rs1729951 0.575 rs12494558 chr3:136678781 C/G cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs903263 0.965 rs2134648 chr1:84662941 C/T cg09664975 chr1:84543551 PRKACB 0.48 4.54 0.38 1.31e-5 Breast cancer (male); TGCT cis rs854765 0.624 rs7359509 chr17:17741875 A/G cg09796270 chr17:17721594 SREBF1 -0.27 -5.19 -0.42 8.39e-7 Total body bone mineral density; TGCT cis rs2180341 0.960 rs1543432 chr6:127698018 T/C cg27446573 chr6:127587934 RNF146 1.16 10.52 0.69 6.95e-19 Breast cancer; TGCT cis rs12210905 0.688 rs72841397 chr6:27488423 C/A cg08851530 chr6:28072375 NA 1.32 6.02 0.48 1.85e-8 Hip circumference adjusted for BMI; TGCT cis rs9549260 0.640 rs4943796 chr13:41196016 C/T cg21288729 chr13:41239152 FOXO1 1.0 10.23 0.68 3.52e-18 Red blood cell count; TGCT cis rs10464366 0.746 rs62442210 chr7:39146328 G/T cg15212455 chr7:39170539 POU6F2 0.26 5.9 0.47 3.21e-8 IgG glycosylation; TGCT cis rs11785400 0.731 rs4736363 chr8:143742112 C/A cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs2730260 0.537 rs56260213 chr7:158875921 C/T cg02078164 chr7:157982224 PTPRN2 0.41 4.58 0.38 1.11e-5 Myopia (pathological); TGCT cis rs7224685 0.569 rs34356467 chr17:3978531 G/T cg09580393 chr17:4869866 SPAG7 -0.39 -4.5 -0.37 1.56e-5 Type 2 diabetes; TGCT cis rs2839186 0.967 rs2839191 chr21:47695395 C/G cg13732083 chr21:47605072 C21orf56 0.34 4.6 0.38 1.02e-5 Testicular germ cell tumor; TGCT cis rs59107033 0.607 rs57572875 chr3:123126268 T/C cg04890266 chr3:123102914 ADCY5 -0.39 -5.79 -0.46 5.33e-8 Lymphocyte counts; TGCT cis rs6163 0.727 rs284862 chr10:104572081 C/T cg04362960 chr10:104952993 NT5C2 -0.52 -4.55 -0.38 1.26e-5 Waist circumference;Hip circumference; TGCT cis rs7833790 0.724 rs72603871 chr8:82754460 C/G cg17211192 chr8:82754475 SNX16 0.97 9.09 0.63 2.04e-15 Diastolic blood pressure; TGCT cis rs7845219 0.544 rs10956930 chr8:95919786 C/G cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7659604 0.539 rs3217753 chr4:122746325 A/G cg20573242 chr4:122745356 CCNA2 0.64 5.76 0.46 6.37e-8 Type 2 diabetes; TGCT cis rs9583531 0.660 rs80030913 chr13:111336866 G/C cg15747390 chr13:111297551 CARS2 0.88 5.97 0.47 2.32e-8 Coronary artery disease; TGCT cis rs7772486 0.754 rs702324 chr6:146008793 A/G cg05347473 chr6:146136440 FBXO30 -0.53 -4.86 -0.4 3.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4664308 0.870 rs2305818 chr2:161029218 G/A cg03641300 chr2:160917029 PLA2R1 -0.28 -6.9 -0.53 2.38e-10 Idiopathic membranous nephropathy; TGCT cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg23982607 chr1:1823379 GNB1 -0.35 -4.61 -0.38 9.8e-6 Body mass index; TGCT cis rs4851266 0.966 rs4851270 chr2:100832656 T/C cg07810366 chr2:100720526 AFF3 -0.37 -5.33 -0.43 4.53e-7 Educational attainment; TGCT cis rs2204008 0.652 rs11520002 chr12:38022179 G/T cg26384229 chr12:38710491 ALG10B 0.85 7.63 0.57 5.5e-12 Bladder cancer; TGCT cis rs17270561 1.000 rs12211184 chr6:25823774 G/A cg17691542 chr6:26056736 HIST1H1C 0.78 4.78 0.39 4.87e-6 Iron status biomarkers; TGCT cis rs12762955 0.561 rs10752022 chr10:1043798 C/T cg18964960 chr10:1102726 WDR37 -0.69 -6.08 -0.48 1.35e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs28595532 0.920 rs17323034 chr4:119606518 G/A cg14228332 chr4:119757509 SEC24D 1.0 5.76 0.46 6.22e-8 Cannabis dependence symptom count; TGCT cis rs1933488 0.835 rs9371280 chr6:153414273 T/C cg24028809 chr6:153414101 RGS17 0.21 4.67 0.39 7.69e-6 Prostate cancer; TGCT cis rs2692947 0.696 rs1724121 chr2:96808549 T/C cg23100626 chr2:96804247 ASTL 0.44 5.45 0.44 2.57e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs1371867 0.846 rs1788182 chr8:101334620 C/T cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT trans rs10506458 0.688 rs73127095 chr12:63418283 T/G cg22491629 chr6:157744540 C6orf35 -0.8 -6.96 -0.53 1.72e-10 Hemostatic factors and hematological phenotypes; TGCT cis rs3784262 0.669 rs4646592 chr15:58302557 A/G cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.83e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs727563 0.638 rs4820443 chr22:42193913 A/G cg06481639 chr22:41940642 POLR3H -0.67 -5.95 -0.47 2.57e-8 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7666738 0.791 rs62318641 chr4:98816964 T/C cg05340658 chr4:99064831 C4orf37 0.51 6.03 0.48 1.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3617 0.625 rs11715347 chr3:52883070 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg01570182 chr17:44337453 NA 1.07 9.81 0.66 3.57e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7666738 0.753 rs35146453 chr4:98902278 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.81 0.4 4.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1971762 0.542 rs12303370 chr12:54091807 A/C cg16917193 chr12:54089295 NA 1.27 16.81 0.83 9.11e-34 Height; TGCT cis rs11098499 0.954 rs10008459 chr4:120394231 T/C cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs3733585 0.699 rs6449176 chr4:9967843 G/A cg11266682 chr4:10021025 SLC2A9 -0.59 -7.85 -0.58 1.7e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9883204 0.951 rs6794202 chr3:123093887 C/T cg04890266 chr3:123102914 ADCY5 0.36 5.08 0.42 1.34e-6 Birth weight; TGCT cis rs854765 0.647 rs712267 chr17:18021607 G/A cg04398451 chr17:18023971 MYO15A -0.39 -6.75 -0.52 5e-10 Total body bone mineral density; TGCT cis rs67311347 1.000 rs28707772 chr3:40504666 G/A cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs2239547 0.603 rs71301807 chr3:53085475 C/G cg11645453 chr3:52864694 ITIH4 0.3 4.8 0.4 4.47e-6 Schizophrenia; TGCT cis rs4253772 0.591 rs6519993 chr22:46656479 A/G cg09491104 chr22:46646882 C22orf40 -0.63 -6.39 -0.5 3.05e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs2836950 0.585 rs1029004 chr21:40615343 A/G cg06238570 chr21:40685208 BRWD1 -0.6 -6.31 -0.49 4.57e-9 Menarche (age at onset); TGCT cis rs13008689 0.875 rs12616139 chr2:8522651 C/T cg11358199 chr2:8453529 NA 0.28 4.61 0.38 1.01e-5 Longevity; TGCT cis rs9357506 1.000 rs6910987 chr6:46307619 A/G cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT trans rs11088226 0.681 rs16989507 chr21:33939509 T/G cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT cis rs12908161 1.000 rs17601029 chr15:85347709 A/G cg12863693 chr15:85201151 NMB 0.42 5.03 0.41 1.7e-6 Schizophrenia; TGCT cis rs9858542 0.953 rs67216675 chr3:49493151 G/T cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6089829 0.962 rs2277769 chr20:61666805 C/T cg08564027 chr20:61660810 NA 0.37 6.65 0.51 8.49e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs988712 0.705 rs4923457 chr11:27648580 A/T cg10635145 chr11:27742435 BDNF -0.38 -5.23 -0.43 7e-7 Obesity; TGCT cis rs56104184 0.615 rs73061693 chr19:49399941 C/A cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2288884 1.000 rs17835749 chr19:52578695 C/G cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg11845111 chr2:191398756 TMEM194B 0.36 5.51 0.44 1.97e-7 Pulse pressure; TGCT trans rs1496653 0.602 rs13090125 chr3:23581248 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1568889 1.000 rs7933332 chr11:28036392 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.86 8.94 0.63 4.66e-15 Bipolar disorder; TGCT cis rs4819052 0.851 rs2838831 chr21:46664775 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.59 4.9 0.4 2.99e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs76788097 0.614 rs7151034 chr14:61820669 T/G cg01084740 chr14:61748243 TMEM30B -0.65 -4.64 -0.38 8.6e-6 Marginal zone lymphoma; TGCT cis rs1552244 0.700 rs9833566 chr3:9981671 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.25 -0.49 6.15e-9 Alzheimer's disease; TGCT trans rs1973993 0.967 rs10875017 chr1:96949526 C/T cg10631902 chr5:14652156 NA 0.3 6.93 0.53 2.08e-10 Weight; TGCT cis rs1171582 0.545 rs1877792 chr10:61520003 G/T cg23572703 chr10:62241191 NA -0.26 -4.46 -0.37 1.84e-5 Alopecia areata; TGCT cis rs10823500 0.748 rs7072230 chr10:71978144 A/G cg04118878 chr10:71993077 PPA1 0.57 5.25 0.43 6.25e-7 Blood protein levels; TGCT cis rs7786808 0.615 rs1563066 chr7:158194935 A/C cg01191920 chr7:158217561 PTPRN2 -0.41 -6.14 -0.48 1.03e-8 Obesity-related traits; TGCT cis rs12360000 0.864 rs11250837 chr10:1901013 C/T cg26364871 chr10:1889757 NA 0.41 4.64 0.38 8.81e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs10893109 0.967 rs10736534 chr11:123807033 C/A cg14126608 chr11:122846540 NA -0.28 -4.58 -0.38 1.12e-5 Facial morphology (factor 13, vertical position of alar curvature relative to upper lip); TGCT cis rs611744 0.647 rs631775 chr8:109252746 T/C cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7267979 1.000 rs2297497 chr20:25297909 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9325144 0.647 rs61937754 chr12:39060543 T/C cg26384229 chr12:38710491 ALG10B -0.56 -5.1 -0.42 1.25e-6 Morning vs. evening chronotype; TGCT cis rs1894292 0.505 rs10938078 chr4:74375447 A/G cg05868023 chr4:75230803 EREG -0.54 -4.95 -0.41 2.35e-6 Prostate cancer; TGCT cis rs151997 0.671 rs152099 chr5:50210091 A/G cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs17376456 0.825 rs13361613 chr5:93272176 C/T cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs7172809 0.573 rs12324366 chr15:77547102 G/C cg22256960 chr15:77711686 NA -0.47 -4.61 -0.38 9.99e-6 Glucose homeostasis traits; TGCT cis rs56116382 0.604 rs9858428 chr3:49877585 G/T cg00383909 chr3:49044727 WDR6 1.27 6.28 0.49 5.15e-9 Intelligence (multi-trait analysis);High light scatter reticulocyte count; TGCT trans rs916888 0.647 rs199524 chr17:44848438 G/T cg10053473 chr17:62856997 LRRC37A3 0.4 6.73 0.52 5.74e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1018836 0.923 rs2213886 chr8:91554163 G/C cg16814680 chr8:91681699 NA -0.89 -9.81 -0.66 3.73e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1799949 1.000 rs34059614 chr17:41303071 C/T cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs910316 1.000 rs2098297 chr14:75619118 G/T cg08847533 chr14:75593920 NEK9 -0.97 -10.82 -0.7 1.28e-19 Height; TGCT cis rs6025261 0.761 rs6099359 chr20:55509896 G/T cg04763273 chr20:55502381 NA -0.28 -4.45 -0.37 1.88e-5 Verbal memory performance (delayed recall level); TGCT cis rs11030122 0.959 rs7118295 chr11:3903103 T/C cg18678763 chr11:4115507 RRM1 -0.39 -4.48 -0.37 1.66e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs910316 0.712 rs175037 chr14:75465038 T/C cg11812906 chr14:75593930 NEK9 -0.59 -5.69 -0.45 8.84e-8 Height; TGCT cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs7412746 0.658 rs11204739 chr1:150865760 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.5 0.37 1.53e-5 Melanoma; TGCT cis rs9858542 0.537 rs4410472 chr3:49329090 A/T cg00383909 chr3:49044727 WDR6 0.65 4.44 0.37 1.97e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7178424 0.875 rs28513564 chr15:62232360 C/T cg00456672 chr15:62358751 C2CD4A -0.3 -4.48 -0.37 1.69e-5 Height; TGCT trans rs3780486 0.846 rs10971419 chr9:33124161 T/C cg20290983 chr6:43655470 MRPS18A 1.18 14.81 0.8 3.33e-29 IgG glycosylation; TGCT cis rs7772486 0.754 rs2328707 chr6:146053498 G/A cg13319975 chr6:146136371 FBXO30 0.56 5.0 0.41 1.9e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10089 1.000 rs3792866 chr5:127479900 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.77 7.31 0.55 2.9100000000000002e-11 Ileal carcinoids; TGCT cis rs2014572 0.967 rs11084492 chr19:57756026 A/T cg24459738 chr19:57751996 ZNF805 -0.54 -5.4 -0.44 3.21e-7 Hyperactive-impulsive symptoms; TGCT trans rs727979 1.000 rs34429158 chr6:149605712 G/A cg00895196 chr6:22147182 FLJ22536 0.41 6.69 0.51 6.9e-10 Hemostatic factors and hematological phenotypes; TGCT cis rs682748 0.844 rs297206 chr5:17126682 G/A cg23987134 chr5:17158319 LOC285696 -0.19 -4.44 -0.37 1.97e-5 Hippocampal atrophy; TGCT cis rs72615157 0.697 rs2056726 chr7:99780283 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.67 5.25 0.43 6.3e-7 Lung function (FEV1/FVC); TGCT cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.22 -0.42 7.39e-7 Bipolar disorder; TGCT trans rs17684571 0.938 rs4074101 chr6:56562452 G/A cg14229071 chr15:89282588 NA 0.52 6.82 0.52 3.54e-10 Schizophrenia; TGCT cis rs9790314 0.905 rs4518145 chr3:160950030 T/C cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs7226408 0.857 rs8094856 chr18:34548299 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs929354 0.806 rs28446734 chr7:156996775 T/C cg05182265 chr7:156933206 UBE3C -0.38 -8.59 -0.61 3.18e-14 Body mass index; TGCT cis rs12681287 0.752 rs7822268 chr8:87306440 G/T cg27223183 chr8:87520930 FAM82B -0.85 -6.4 -0.5 2.9e-9 Caudate activity during reward; TGCT cis rs6665290 0.935 rs1929864 chr1:227195500 T/G cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs7772486 0.875 rs2814863 chr6:146347299 C/T cg23711669 chr6:146136114 FBXO30 -0.87 -9.53 -0.65 1.75e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2251381 0.606 rs8129515 chr21:30520167 C/G cg24692254 chr21:30365293 RNF160 0.69 6.71 0.52 6.16e-10 Selective IgA deficiency; TGCT cis rs17221829 0.733 rs12283497 chr11:89357907 G/A cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs9921338 0.923 rs7186455 chr16:11427748 A/G cg00044050 chr16:11439710 C16orf75 -0.93 -7.36 -0.55 2.27e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs36051895 0.623 rs10118267 chr9:5243736 T/C cg02405213 chr9:5042618 JAK2 -0.7 -8.33 -0.6 1.29e-13 Pediatric autoimmune diseases; TGCT cis rs7429990 0.901 rs6442102 chr3:48152562 A/G cg11946769 chr3:48343235 NME6 -0.56 -4.61 -0.38 9.72e-6 Educational attainment (years of education); TGCT cis rs7666738 0.546 rs11097591 chr4:98910173 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.5 0.37 1.55e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs112591243 0.685 rs2839341 chr21:47990008 A/G cg10657630 chr21:48055338 PRMT2 -1.0 -5.29 -0.43 5.4e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs7570971 0.500 rs13413101 chr2:135859371 A/T cg07169764 chr2:136633963 MCM6 0.59 5.08 0.42 1.33e-6 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs7255045 0.742 rs10407116 chr19:12962272 G/A cg23899408 chr19:12877188 HOOK2 -0.61 -4.99 -0.41 1.97e-6 Mean corpuscular volume; TGCT cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs1857353 0.803 rs74089245 chr1:75901600 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs17253792 0.822 rs10083499 chr14:56066590 T/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3820068 0.581 rs1547031 chr1:15918960 G/A cg05660106 chr1:15850417 CASP9 0.81 8.15 0.59 3.31e-13 Systolic blood pressure; TGCT cis rs2204008 0.640 rs11520199 chr12:38211026 T/C cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs9814567 1.000 rs9834755 chr3:134206845 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6938 0.534 rs11636892 chr15:75266049 G/C cg09165964 chr15:75287851 SCAMP5 0.51 4.65 0.39 8.33e-6 Breast cancer; TGCT cis rs2153535 0.580 rs1855769 chr6:8473095 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1008375 1.000 rs4698198 chr4:17656536 G/A cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7647973 0.588 rs62262675 chr3:49673662 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.59 -0.38 1.08e-5 Menarche (age at onset); TGCT cis rs9926296 0.715 rs467035 chr16:89740285 C/G cg01097406 chr16:89675127 NA -0.31 -5.59 -0.45 1.39e-7 Vitiligo; TGCT cis rs7412746 0.658 rs59988025 chr1:150940358 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.72 0.39 6.28e-6 Melanoma; TGCT cis rs6684514 1.000 rs10908495 chr1:156263940 T/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs478304 0.654 rs11601509 chr11:65456864 T/C cg27068330 chr11:65405492 SIPA1 -0.99 -11.36 -0.71 6.13e-21 Acne (severe); TGCT trans rs9951602 0.512 rs1903722 chr18:76646539 G/A cg02800362 chr5:177631904 HNRNPAB 1.14 13.02 0.76 6.04e-25 Obesity-related traits; TGCT cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg03161606 chr19:29218774 NA 0.6 5.84 0.46 4.28e-8 Methadone dose in opioid dependence; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.71 0.39 6.56e-6 Lymphocyte counts; TGCT cis rs1372520 0.623 rs2583975 chr4:90748488 T/C cg20003494 chr4:90757398 SNCA -0.59 -4.63 -0.38 9.21e-6 Neuroticism; TGCT cis rs1691799 0.899 rs1168294 chr12:66733988 T/C cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs7089973 0.604 rs2420065 chr10:116583753 A/G cg03647239 chr10:116582469 FAM160B1 0.58 5.63 0.45 1.16e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs2032447 0.639 rs198810 chr6:26128618 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.84 -8.92 -0.63 5.13e-15 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.715 rs11657238 chr17:46985634 A/G cg26022315 chr17:47021804 SNF8 0.54 5.37 0.43 3.73e-7 Type 2 diabetes; TGCT cis rs644799 0.763 rs2950521 chr11:95536870 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs910316 0.967 rs2010678 chr14:75567178 C/T cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT cis rs61677309 1.000 rs1945765 chr11:118182829 T/A cg11038285 chr11:118016290 SCN4B -0.49 -4.52 -0.38 1.41e-5 Lung cancer in ever smokers; TGCT cis rs2404602 0.692 rs36070630 chr15:76949259 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.17e-6 Blood metabolite levels; TGCT cis rs7819412 0.511 rs35558344 chr8:11434232 C/T cg21775007 chr8:11205619 TDH -0.54 -5.13 -0.42 1.07e-6 Triglycerides; TGCT cis rs4555082 1.000 rs4334224 chr14:105759198 C/T cg10792982 chr14:105748885 BRF1 0.22 4.53 0.38 1.39e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs7191700 0.511 rs12923756 chr16:11359675 C/T cg00044050 chr16:11439710 C16orf75 -0.81 -8.38 -0.6 9.95e-14 Multiple sclerosis; TGCT cis rs225245 0.791 rs720774 chr17:34017453 T/G cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg04389838 chr3:44770851 ZNF501 -0.36 -4.73 -0.39 5.91e-6 Depressive symptoms; TGCT cis rs7302981 0.900 rs836180 chr12:50503269 C/T cg23855989 chr12:50355821 AQP5 0.3 4.44 0.37 2e-5 Systolic blood pressure; TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg07167872 chr1:205819463 PM20D1 0.57 7.37 0.55 2.12e-11 Menarche (age at onset); TGCT cis rs12950390 0.853 rs11655112 chr17:45856563 T/C cg03474202 chr17:45855739 NA -0.44 -4.51 -0.38 1.5e-5 IgG glycosylation; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg04234412 chr22:24373322 LOC391322 0.93 12.12 0.74 8.62e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10193935 0.892 rs12612372 chr2:42414035 A/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4919044 0.740 rs73319304 chr10:94777045 A/G cg05127821 chr10:94822908 CYP26C1 -0.77 -5.03 -0.41 1.71e-6 Coronary artery disease; TGCT cis rs9611519 0.929 rs4820423 chr22:41430338 A/T cg13695892 chr22:41940480 POLR3H -0.53 -4.62 -0.38 9.54e-6 Neuroticism; TGCT cis rs9911578 1.000 rs437732 chr17:56675861 A/C cg12560992 chr17:57184187 TRIM37 0.76 9.16 0.64 1.32e-15 Intelligence (multi-trait analysis); TGCT cis rs3892630 0.824 rs12327732 chr19:33221767 C/T cg22980127 chr19:33182716 NUDT19 0.71 5.15 0.42 9.79e-7 Red blood cell traits; TGCT cis rs3785574 0.962 rs7219920 chr17:61811642 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.85 0.47 4.05e-8 Height; TGCT cis rs9926296 0.632 rs4785716 chr16:89801127 T/C cg26513180 chr16:89883248 FANCA 0.71 6.86 0.52 2.86e-10 Vitiligo; TGCT cis rs3796352 1.000 rs11706035 chr3:53011868 A/T cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2066819 1.000 rs116535779 chr12:56739261 A/G cg26714650 chr12:56694279 CS -1.55 -8.12 -0.59 4e-13 Psoriasis vulgaris; TGCT cis rs9527 0.615 rs7917295 chr10:104701187 A/G cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs910316 0.763 rs2080201 chr14:75629972 C/T cg11812906 chr14:75593930 NEK9 -0.64 -5.91 -0.47 3.14e-8 Height; TGCT cis rs644799 1.000 rs527899 chr11:95529242 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9814567 0.896 rs7642266 chr3:134346025 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.8 -7.29 -0.55 3.14e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs736408 0.812 rs2071507 chr3:52826707 G/A cg07507251 chr3:52567010 NT5DC2 0.41 5.62 0.45 1.2e-7 Bipolar disorder; TGCT cis rs35306767 0.622 rs66462130 chr10:1022108 C/T cg18964960 chr10:1102726 WDR37 0.74 5.25 0.43 6.39e-7 Eosinophil percentage of granulocytes; TGCT cis rs7153648 1.000 rs7153648 chr14:61122526 C/G cg27398547 chr14:60952738 C14orf39 1.47 8.35 0.6 1.12e-13 Prostate cancer; TGCT cis rs7223966 0.960 rs11659013 chr17:61869559 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs13256369 1.000 rs10098234 chr8:8576692 G/A cg06671706 chr8:8559999 CLDN23 0.35 4.69 0.39 6.95e-6 Obesity-related traits; TGCT cis rs2014572 0.967 rs10413037 chr19:57771883 A/G cg24459738 chr19:57751996 ZNF805 -0.6 -5.92 -0.47 2.96e-8 Hyperactive-impulsive symptoms; TGCT cis rs9581857 0.512 rs9652092 chr13:28074855 T/C cg22138327 chr13:27999177 GTF3A 0.85 6.02 0.48 1.87e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2204008 0.713 rs11173567 chr12:38089375 T/C cg13010199 chr12:38710504 ALG10B 0.6 4.82 0.4 4.06e-6 Bladder cancer; TGCT trans rs1005277 0.541 rs2263163 chr10:38389887 G/A cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs17539620 0.628 rs62432729 chr6:154830044 T/C cg20019720 chr6:154832845 CNKSR3 0.52 4.53 0.38 1.36e-5 Lipoprotein (a) levels; TGCT cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg21171335 chr12:122356390 WDR66 0.56 5.48 0.44 2.23e-7 Mean corpuscular volume; TGCT cis rs7582180 0.629 rs34745556 chr2:100942506 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs1018836 0.544 rs2339154 chr8:91459316 T/C cg16814680 chr8:91681699 NA -0.57 -5.59 -0.45 1.4e-7 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs12464483 0.524 rs2256411 chr2:30886860 C/A cg12454169 chr2:30669597 LCLAT1 0.44 4.87 0.4 3.29e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs12510870 0.634 rs12508974 chr4:74394321 G/A cg05868023 chr4:75230803 EREG -0.55 -4.8 -0.4 4.53e-6 Iris color (b* coordinate); TGCT trans rs61931739 0.500 rs34287388 chr12:34444626 C/A cg26384229 chr12:38710491 ALG10B 0.73 6.93 0.53 2e-10 Morning vs. evening chronotype; TGCT trans rs6089829 0.962 rs7273930 chr20:61666017 G/A cg17470723 chr8:74884337 TCEB1 0.74 7.08 0.54 9.28e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs807669 0.835 rs1780639 chr22:19174603 T/C cg02655711 chr22:19163373 SLC25A1 0.42 9.92 0.67 1.94e-17 Metabolite levels; TGCT cis rs7192750 0.586 rs4788571 chr16:71920823 G/A cg06353428 chr16:71660113 MARVELD3 0.8 7.2 0.54 5.05e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs854765 0.693 rs8079321 chr17:17760789 C/T cg04398451 chr17:18023971 MYO15A -0.29 -4.57 -0.38 1.15e-5 Total body bone mineral density; TGCT cis rs7552404 0.924 rs1694419 chr1:76219801 C/T cg03433033 chr1:76189801 ACADM 0.68 6.95 0.53 1.86e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7659604 1.000 rs10016433 chr4:122664771 A/G cg19748678 chr4:122722346 EXOSC9 0.57 5.5 0.44 2.07e-7 Type 2 diabetes; TGCT cis rs1215050 0.740 rs700739 chr4:99022546 A/G cg17366294 chr4:99064904 C4orf37 -0.54 -5.86 -0.47 3.98e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7829975 0.871 rs572307 chr8:8578811 T/C cg15556689 chr8:8085844 FLJ10661 -0.67 -5.84 -0.46 4.31e-8 Mood instability; TGCT cis rs12908161 0.959 rs12908699 chr15:85240403 G/T cg17173187 chr15:85201210 NMB 0.59 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs295140 1.000 rs13026151 chr2:201164570 T/A cg04283868 chr2:201171347 SPATS2L 0.63 6.39 0.5 3.03e-9 QT interval; TGCT cis rs7917772 0.636 rs2250580 chr10:104505687 C/G cg05855489 chr10:104503620 C10orf26 -0.73 -5.35 -0.43 4.1e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2439831 1.000 rs689596 chr15:43761717 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs2839186 0.500 rs13052701 chr21:47660045 A/T cg12516959 chr21:47718080 NA -0.33 -4.58 -0.38 1.1e-5 Testicular germ cell tumor; TGCT cis rs9611565 0.921 rs5751081 chr22:41742788 A/T cg03806693 chr22:41940476 POLR3H -0.87 -9.3 -0.64 6.07e-16 Vitiligo; TGCT cis rs919433 0.680 rs7605813 chr2:198375329 C/G cg00792783 chr2:198669748 PLCL1 0.5 4.6 0.38 1.01e-5 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs250677 1.000 rs36079 chr5:148430504 G/A cg23229984 chr5:148520753 ABLIM3 0.21 5.28 0.43 5.5e-7 Breast cancer; TGCT cis rs1534166 0.647 rs7355929 chr3:133514190 C/T cg16414030 chr3:133502952 NA 0.44 5.71 0.46 7.92e-8 Alcohol consumption (transferrin glycosylation); TGCT cis rs6500602 0.535 rs758044 chr16:4431202 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.35 4.95 0.41 2.37e-6 Schizophrenia; TGCT cis rs9549367 0.664 rs9549689 chr13:113848387 G/A cg18105134 chr13:113819100 PROZ -0.46 -8.3 -0.6 1.46e-13 Platelet distribution width; TGCT cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs986417 0.901 rs1955697 chr14:61028435 T/C cg27398547 chr14:60952738 C14orf39 1.49 10.43 0.68 1.12e-18 Gut microbiota (bacterial taxa); TGCT cis rs3820928 1.000 rs6723774 chr2:227770592 C/T cg11843606 chr2:227700838 RHBDD1 0.51 4.51 0.38 1.47e-5 Pulmonary function; TGCT trans rs28735056 0.904 rs62103183 chr18:77626564 A/G cg05926928 chr17:57297772 GDPD1 0.65 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs7829975 0.577 rs7816329 chr8:8543843 G/A cg17143192 chr8:8559678 CLDN23 -0.52 -5.21 -0.42 7.57e-7 Mood instability; TGCT cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg03060546 chr3:49711283 APEH 0.58 5.59 0.45 1.38e-7 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs1670533 1.000 rs2014318 chr4:1068778 C/T cg27284194 chr4:1044797 NA -0.69 -5.99 -0.47 2.14e-8 Recombination rate (females); TGCT cis rs939658 0.776 rs4778925 chr15:79443791 C/T cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs4727027 0.933 rs917123 chr7:148848358 G/A cg23583168 chr7:148888333 NA -0.77 -10.1 -0.67 7.35e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2762353 0.603 rs10946798 chr6:25781853 T/G cg03264133 chr6:25882463 NA 0.49 4.94 0.41 2.51e-6 Blood metabolite levels; TGCT cis rs8017423 0.967 rs7146640 chr14:90720114 C/T cg04374321 chr14:90722782 PSMC1 -0.75 -7.54 -0.56 8.48e-12 Mortality in heart failure; TGCT cis rs6671200 0.541 rs3738170 chr1:95699604 G/C cg20701556 chr1:95698924 RWDD3 -0.52 -5.27 -0.43 5.76e-7 Stearic acid (18:0) levels; TGCT cis rs8051431 0.876 rs4788589 chr16:72019948 A/T cg06353428 chr16:71660113 MARVELD3 -0.59 -4.74 -0.39 5.73e-6 LDL cholesterol levels; TGCT cis rs2836974 0.932 rs8128734 chr21:40569511 G/A cg11890956 chr21:40555474 PSMG1 1.11 12.17 0.74 6.69e-23 Cognitive function; TGCT cis rs11578119 0.933 rs12120718 chr1:170394250 A/T cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.67e-8 Male-pattern baldness; TGCT cis rs6545883 0.868 rs6545887 chr2:61828818 C/G cg15711740 chr2:61764176 XPO1 -0.6 -5.69 -0.45 8.69e-8 Tuberculosis; TGCT cis rs5758343 1 rs5758343 chr22:41816652 A/T cg06481639 chr22:41940642 POLR3H 0.79 6.93 0.53 2.06e-10 Allergic disease (asthma, hay fever or eczema); TGCT trans rs4650994 0.544 rs6675811 chr1:178499068 T/A cg05059571 chr16:84539110 KIAA1609 -0.54 -11.23 -0.71 1.27e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs72717009 0.825 rs7539468 chr1:161477066 G/A cg23840854 chr1:161414152 NA -0.98 -5.86 -0.47 3.95e-8 Rheumatoid arthritis; TGCT trans rs12339966 0.527 rs10756226 chr9:11285409 G/A cg07173112 chr1:1114698 TTLL10 -0.34 -6.68 -0.51 7.34e-10 Systolic blood pressure; TGCT cis rs12410462 0.681 rs76705164 chr1:227615570 G/A cg23173402 chr1:227635558 NA 0.64 4.44 0.37 1.97e-5 Major depressive disorder; TGCT cis rs2404602 0.647 rs12913024 chr15:77145216 C/T cg22467129 chr15:76604101 ETFA 0.46 4.64 0.38 8.6e-6 Blood metabolite levels; TGCT cis rs3749237 0.595 rs4855859 chr3:49526300 C/T cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs9549260 0.683 rs4941988 chr13:41196006 T/G cg21288729 chr13:41239152 FOXO1 1.0 10.23 0.68 3.52e-18 Red blood cell count; TGCT cis rs6840360 0.615 rs12647465 chr4:152607318 C/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.13 -0.48 1.05e-8 Intelligence (multi-trait analysis); TGCT cis rs80282103 0.867 rs17155821 chr10:1071701 A/G cg15531433 chr10:1639090 ADARB2 0.41 4.51 0.38 1.46e-5 Glomerular filtration rate (creatinine); TGCT cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs7267979 1.000 rs2482928 chr20:25331530 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7226408 0.802 rs11664299 chr18:34485969 A/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9660992 0.547 rs748012 chr1:205216573 C/T cg00857998 chr1:205179979 DSTYK 0.51 4.71 0.39 6.48e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs7267979 0.706 rs6138542 chr20:25207773 C/A cg14121845 chr20:25566513 NINL 0.5 5.45 0.44 2.64e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12643440 0.538 rs6843399 chr4:17140263 A/G cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs2932538 0.922 rs12406906 chr1:113117900 G/T cg22162597 chr1:113214053 CAPZA1 -0.26 -5.76 -0.46 6.28e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs999943 0.846 rs9348923 chr6:33617924 C/T cg14003231 chr6:33640908 ITPR3 0.4 4.98 0.41 2.13e-6 Obesity (extreme); TGCT cis rs7772486 0.641 rs960385 chr6:146371074 G/A cg13319975 chr6:146136371 FBXO30 -0.65 -6.11 -0.48 1.2e-8 Lobe attachment (rater-scored or self-reported); TGCT trans rs1814175 0.616 rs1722001 chr11:49894427 A/G cg11707556 chr5:10655725 ANKRD33B -0.45 -11.08 -0.71 3.01e-20 Height; TGCT cis rs56104184 0.830 rs73061622 chr19:49358111 C/T cg21252483 chr19:49399788 TULP2 -0.37 -4.73 -0.39 5.96e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9383153 1.000 rs9370887 chr6:16329258 G/C cg13189271 chr6:15365693 JARID2 0.92 4.5 0.37 1.57e-5 Gambling; TGCT cis rs7647973 0.925 rs4955439 chr3:49245645 G/T cg06212747 chr3:49208901 KLHDC8B -0.58 -4.74 -0.39 5.85e-6 Menarche (age at onset); TGCT cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg08219700 chr8:58056026 NA 0.37 6.07 0.48 1.47e-8 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg06238570 chr21:40685208 BRWD1 0.82 8.95 0.63 4.29e-15 Cognitive function; TGCT cis rs7666738 0.830 rs34870112 chr4:99045815 T/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7833790 1.000 rs7833790 chr8:82731157 T/C cg17211192 chr8:82754475 SNX16 -1.03 -8.73 -0.62 1.44e-14 Diastolic blood pressure; TGCT cis rs7208859 0.673 rs9898858 chr17:29156211 A/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7178424 0.516 rs12901575 chr15:62338462 C/G cg00456672 chr15:62358751 C2CD4A -0.29 -4.45 -0.37 1.88e-5 Height; TGCT cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg02458000 chr6:26745757 NA -0.5 -4.55 -0.38 1.29e-5 Intelligence (multi-trait analysis); TGCT cis rs1348850 0.914 rs12469386 chr2:178358281 A/G cg22681709 chr2:178499509 PDE11A 0.35 4.69 0.39 6.97e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs8177253 1.000 rs8177248 chr3:133479626 C/T cg01448562 chr3:133502909 NA -0.33 -6.24 -0.49 6.44e-9 Iron status biomarkers; TGCT cis rs3796352 1.000 rs17052727 chr3:53070914 T/C cg15956490 chr3:53032818 SFMBT1 0.56 6.51 0.5 1.67e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9549260 0.755 rs7990923 chr13:41215972 A/G cg21288729 chr13:41239152 FOXO1 0.97 10.09 0.67 7.57e-18 Red blood cell count; TGCT cis rs11190604 1.000 rs3750719 chr10:102248950 C/G cg16342193 chr10:102329863 NA -0.41 -5.34 -0.43 4.32e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs72781680 0.898 rs6712175 chr2:24023431 T/G cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs2832191 0.716 rs1888440 chr21:30454484 C/T cg08807101 chr21:30365312 RNF160 0.65 6.14 0.48 1.03e-8 Dental caries; TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs9522267 0.535 rs12583489 chr13:112233455 G/A cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs986417 0.901 rs12886086 chr14:61042091 A/G cg27398547 chr14:60952738 C14orf39 1.55 9.13 0.63 1.62e-15 Gut microbiota (bacterial taxa); TGCT cis rs992157 1.000 rs736731 chr2:219120588 A/G cg00012203 chr2:219082015 ARPC2 0.77 8.2 0.59 2.56e-13 Colorectal cancer; TGCT cis rs6545883 0.929 rs2694625 chr2:61616055 G/A cg15711740 chr2:61764176 XPO1 0.54 4.78 0.39 4.85e-6 Tuberculosis; TGCT cis rs11098499 0.644 rs3986377 chr4:120260270 G/A cg09307838 chr4:120376055 NA 0.53 5.16 0.42 9.36e-7 Corneal astigmatism; TGCT cis rs8013055 0.846 rs10139744 chr14:105974696 G/A cg25008857 chr14:105974488 NA 0.27 4.44 0.37 1.98e-5 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs72615157 0.613 rs56089143 chr7:99819844 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.6 -4.99 -0.41 1.97e-6 Lung function (FEV1/FVC); TGCT cis rs2730245 0.527 rs62475645 chr7:158656825 G/A cg11984989 chr7:158649758 WDR60 1.0 7.7 0.57 3.71e-12 Height; TGCT cis rs4975616 0.714 rs37007 chr5:1352372 G/C cg07493874 chr5:1342172 CLPTM1L -0.24 -5.23 -0.43 7.03e-7 Lung cancer; TGCT cis rs1018836 0.923 rs1476427 chr8:91552791 A/G cg16814680 chr8:91681699 NA 0.82 9.38 0.64 3.97e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs478304 0.654 rs7115734 chr11:65458964 G/A cg27068330 chr11:65405492 SIPA1 -0.99 -11.36 -0.71 6.13e-21 Acne (severe); TGCT cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg26818010 chr10:134567672 INPP5A -0.38 -5.19 -0.42 8.5e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs10791097 0.967 rs1944142 chr11:130717440 C/T cg05962950 chr11:130786565 SNX19 0.74 7.92 0.58 1.15e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs861020 1.000 rs622832 chr1:209974232 A/C cg05527609 chr1:210001259 C1orf107 0.9 7.25 0.55 3.93e-11 Orofacial clefts; TGCT cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg05368731 chr17:41323189 NBR1 1.2 14.59 0.79 1.08e-28 Menopause (age at onset); TGCT cis rs9311474 0.596 rs524986 chr3:52228496 T/C cg10802521 chr3:52805072 NEK4 -0.56 -6.12 -0.48 1.11e-8 Electroencephalogram traits; TGCT cis rs4711336 1.000 rs764754 chr6:33658310 C/T cg14003231 chr6:33640908 ITPR3 0.28 4.5 0.37 1.54e-5 Height; TGCT cis rs881375 0.678 rs7031752 chr9:123663482 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.52 5.68 0.45 9.15e-8 Rheumatoid arthritis; TGCT cis rs10504229 0.906 rs7846666 chr8:58172302 T/C cg08280861 chr8:58055591 NA 0.32 4.49 0.37 1.63e-5 Developmental language disorder (linguistic errors); TGCT cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2657888 0.965 rs2657903 chr12:56933722 G/A cg23002907 chr12:56915593 RBMS2 0.44 6.15 0.48 9.65e-9 Adiponectin levels; TGCT cis rs1577917 0.958 rs2121594 chr6:86576854 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.6 -0.45 1.34e-7 Response to antipsychotic treatment; TGCT cis rs2179367 0.959 rs544947 chr6:149723548 A/G cg03813151 chr6:149778058 ZC3H12D -0.27 -4.46 -0.37 1.84e-5 Dupuytren's disease; TGCT cis rs586688 0.858 rs492703 chr1:201643782 G/T cg05779441 chr1:201574716 NA 0.28 4.58 0.38 1.11e-5 Obesity-related traits; TGCT cis rs4689592 0.523 rs6446565 chr4:7074027 A/G cg26116260 chr4:7069785 GRPEL1 1.11 10.79 0.7 1.54e-19 Monocyte percentage of white cells; TGCT cis rs8180040 1.000 rs295449 chr3:47375955 G/A cg27129171 chr3:47204927 SETD2 0.7 8.88 0.62 6.43e-15 Colorectal cancer; TGCT cis rs9527 0.662 rs10786714 chr10:104598606 G/C cg15744005 chr10:104629667 AS3MT -0.48 -5.78 -0.46 5.62e-8 Arsenic metabolism; TGCT cis rs72949976 0.646 rs1441170 chr2:214033563 A/G cg08319019 chr2:214017104 IKZF2 -0.83 -8.16 -0.59 3.19e-13 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs3820928 0.874 rs3752896 chr2:227886925 C/T cg11843606 chr2:227700838 RHBDD1 -0.57 -5.23 -0.42 7.12e-7 Pulmonary function; TGCT cis rs4242434 0.927 rs2291232 chr8:22464064 A/G cg03733263 chr8:22462867 KIAA1967 1.12 19.92 0.87 1.83e-40 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs28595532 0.920 rs114207133 chr4:119755140 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6570726 0.967 rs6903252 chr6:145922777 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.93 0.4 2.61e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs892961 0.867 rs6501955 chr17:75414443 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.71 0.52 6.16e-10 Airflow obstruction; TGCT cis rs8180040 0.966 rs7628631 chr3:47560863 C/T cg27129171 chr3:47204927 SETD2 -0.65 -7.54 -0.56 8.69e-12 Colorectal cancer; TGCT cis rs7267979 0.668 rs4815398 chr20:25237338 C/T cg21995068 chr20:25989032 LOC100134868 0.44 5.14 0.42 1.03e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs929354 0.772 rs1182438 chr7:157027438 G/A cg05182265 chr7:156933206 UBE3C 0.4 9.05 0.63 2.54e-15 Body mass index; TGCT cis rs10504229 0.683 rs55714371 chr8:58131846 T/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.604 rs11946375 chr4:1313488 T/C cg03303774 chr4:1407052 NA 0.3 5.0 0.41 1.91e-6 Obesity-related traits; TGCT cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg11890956 chr21:40555474 PSMG1 -0.76 -7.42 -0.55 1.64e-11 Cognitive function; TGCT cis rs1784581 1.000 rs1615717 chr6:162400612 C/T cg17173639 chr6:162384350 PARK2 -0.5 -9.18 -0.64 1.19e-15 Itch intensity from mosquito bite; TGCT cis rs4786125 0.665 rs7201025 chr16:6920592 C/T cg03623568 chr16:6915990 A2BP1 -0.45 -6.77 -0.52 4.65e-10 Heart rate variability traits (SDNN); TGCT cis rs739401 0.611 rs391188 chr11:3047634 G/A cg25174290 chr11:3078921 CARS 0.48 4.68 0.39 7.48e-6 Longevity; TGCT cis rs36051895 0.623 rs57707737 chr9:5062844 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.66 -0.66 8.38e-17 Pediatric autoimmune diseases; TGCT cis rs7647973 0.593 rs59684465 chr3:49874246 C/T cg03060546 chr3:49711283 APEH -0.66 -5.91 -0.47 3.08e-8 Menarche (age at onset); TGCT cis rs4919687 0.550 rs12783444 chr10:104480659 G/A cg05855489 chr10:104503620 C10orf26 0.55 4.43 0.37 2.01e-5 Colorectal cancer; TGCT cis rs453301 0.682 rs2929308 chr8:9084121 T/A cg08975724 chr8:8085496 FLJ10661 -0.52 -4.69 -0.39 7.08e-6 Joint mobility (Beighton score); TGCT cis rs6540559 0.673 rs7511996 chr1:210018473 C/A cg22029157 chr1:209979665 IRF6 0.68 4.88 0.4 3.22e-6 Cleft lip with or without cleft palate; TGCT cis rs17270561 0.723 rs12192635 chr6:25880907 A/T cg17691542 chr6:26056736 HIST1H1C 0.83 5.85 0.47 4.02e-8 Iron status biomarkers; TGCT cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg12310025 chr6:25882481 NA -0.67 -7.28 -0.55 3.31e-11 Blood metabolite levels; TGCT cis rs4654899 1.000 rs10916938 chr1:21446883 A/G cg01072550 chr1:21505969 NA -0.51 -8.27 -0.6 1.76e-13 Superior frontal gyrus grey matter volume; TGCT cis rs57994353 0.865 rs34376913 chr9:139378914 T/C cg13741927 chr9:139327495 INPP5E -0.23 -5.16 -0.42 9.54e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2072499 0.833 rs2251847 chr1:156204047 G/A cg24450063 chr1:156163899 SLC25A44 1.07 11.45 0.72 3.76e-21 Testicular germ cell tumor; TGCT cis rs9296661 0.868 rs1326576 chr6:51667803 G/T cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs1218582 0.772 rs906593 chr1:154885255 G/A cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs36051895 0.559 rs7868706 chr9:5210936 T/G cg02405213 chr9:5042618 JAK2 -0.67 -8.36 -0.6 1.06e-13 Pediatric autoimmune diseases; TGCT cis rs1865760 0.566 rs9467672 chr6:26083904 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs28595532 0.920 rs116516492 chr4:119734247 C/G cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs10992471 0.603 rs7864575 chr9:95304647 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.68 -0.45 9.01e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7666738 0.830 rs13328005 chr4:99055480 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.28 0.43 5.7e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13191362 1.000 rs13193282 chr6:163015442 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg22166914 chr1:53195759 ZYG11B -0.46 -8.42 -0.6 7.72e-14 Monocyte count; TGCT cis rs7666738 0.830 rs13110903 chr4:98946373 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.42 6.05 0.48 1.57e-8 Lymphocyte counts; TGCT cis rs10540 1.000 rs61876340 chr11:495699 A/C cg03934478 chr11:495069 RNH1 0.35 5.82 0.46 4.66e-8 Body mass index; TGCT cis rs68170813 0.559 rs77422419 chr7:106957932 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs6940638 0.744 rs858964 chr6:27142614 C/G cg16675381 chr6:26757706 NA -0.46 -4.46 -0.37 1.84e-5 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs11932942 chr4:98998939 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs881375 1.000 rs10760121 chr9:123647915 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.49 0.44 2.15e-7 Rheumatoid arthritis; TGCT cis rs240764 0.658 rs7451736 chr6:101189901 C/T cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs73198271 0.740 rs10094270 chr8:8646633 G/A cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9329289 0.510 rs2029604 chr10:2554700 T/C cg07014206 chr10:2547000 NA -0.28 -4.62 -0.38 9.42e-6 Age-related hearing impairment; TGCT cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg00786635 chr1:25594202 NA -0.53 -5.35 -0.43 4.1e-7 Erythrocyte sedimentation rate; TGCT cis rs7267979 1.000 rs2257432 chr20:25271086 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9473924 0.542 rs9296645 chr6:50831194 A/G cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs10782582 0.593 rs12131493 chr1:76139172 G/A cg22875332 chr1:76189707 ACADM -0.54 -6.18 -0.49 8.3e-9 Daytime sleep phenotypes; TGCT cis rs854765 0.647 rs8066764 chr17:17974668 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.71 7.23 0.54 4.28e-11 Total body bone mineral density; TGCT cis rs7647973 0.626 rs1078341 chr3:49685592 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs13118159 0.509 rs7688922 chr4:1361011 T/C cg05025164 chr4:1340916 KIAA1530 0.8 6.98 0.53 1.62e-10 Longevity; TGCT cis rs10984561 0.881 rs78544256 chr9:122250437 G/C cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs753778 0.667 rs6578153 chr8:142209543 C/T cg18755752 chr8:142205143 DENND3 -0.27 -5.09 -0.42 1.26e-6 Reticulocyte fraction of red cells;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs244731 0.919 rs12652509 chr5:176626441 A/G cg16006841 chr5:176797999 RGS14 -0.53 -6.95 -0.53 1.88e-10 Urate levels in lean individuals; TGCT cis rs9733 0.596 rs7549795 chr1:150656873 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs208520 0.526 rs4710310 chr6:66802808 T/C cg07460842 chr6:66804631 NA -1.07 -14.74 -0.8 4.84e-29 Exhaled nitric oxide output; TGCT cis rs7714584 0.793 rs12653039 chr5:150252631 G/A cg22134413 chr5:150180641 NA 1.1 8.25 0.6 1.99e-13 Crohn's disease; TGCT cis rs10493773 0.962 rs6698578 chr1:86236676 G/A cg17807903 chr1:86174739 ZNHIT6 -0.37 -4.52 -0.38 1.44e-5 Urate levels in overweight individuals; TGCT cis rs10791097 0.667 rs2155358 chr11:130740357 T/C cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs7618501 0.633 rs4688689 chr3:50035542 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.83 9.04 0.63 2.64e-15 Intelligence (multi-trait analysis); TGCT cis rs7607369 0.580 rs7568196 chr2:219652373 G/A cg01872077 chr2:219646372 CYP27A1 -0.58 -4.8 -0.4 4.54e-6 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs4285028 0.747 rs7153 chr3:121383297 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs13256369 0.774 rs13248423 chr8:8577602 C/G cg17143192 chr8:8559678 CLDN23 0.61 5.6 0.45 1.3e-7 Obesity-related traits; TGCT cis rs3820928 0.934 rs4675117 chr2:227769794 A/G cg11843606 chr2:227700838 RHBDD1 0.51 4.67 0.39 7.64e-6 Pulmonary function; TGCT cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs7174348 1 rs7174348 chr15:78792439 G/A cg24631222 chr15:78858424 CHRNA5 0.61 4.51 0.38 1.5e-5 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs9325144 0.602 rs10785590 chr12:38694145 C/T cg26384229 chr12:38710491 ALG10B 0.66 6.13 0.48 1.09e-8 Morning vs. evening chronotype; TGCT cis rs2932538 0.922 rs12750023 chr1:113118329 G/A cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2933343 0.951 rs7648327 chr3:128570708 A/G cg11901034 chr3:128598214 ACAD9 -0.64 -5.15 -0.42 9.75e-7 IgG glycosylation; TGCT cis rs10256972 0.933 rs35696159 chr7:1047194 A/G cg16145915 chr7:1198662 ZFAND2A -0.39 -4.71 -0.39 6.54e-6 Longevity;Endometriosis; TGCT cis rs780096 0.526 rs7594812 chr2:27611469 A/G cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.46 -0.37 1.84e-5 Total body bone mineral density; TGCT cis rs7267979 0.816 rs6076358 chr20:25519403 G/T cg16686733 chr20:25566563 NINL -0.52 -5.05 -0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4285028 0.848 rs77630152 chr3:121681194 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs2439831 0.850 rs28858500 chr15:44156942 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs9926296 0.512 rs11076626 chr16:89865103 T/A cg21285383 chr16:89894308 SPIRE2 0.46 7.34 0.55 2.41e-11 Vitiligo; TGCT cis rs1153858 0.621 rs12913645 chr15:45555066 G/A cg26924012 chr15:45694286 SPATA5L1 -1.0 -10.91 -0.7 7.59e-20 Homoarginine levels; TGCT cis rs7586879 0.639 rs6749170 chr2:25110962 A/G cg15423357 chr2:25149977 NA 0.48 4.6 0.38 1.03e-5 Body mass index; TGCT cis rs908922 0.676 rs7518654 chr1:152517845 C/G cg20991723 chr1:152506922 NA 0.46 6.15 0.48 9.92e-9 Hair morphology; TGCT cis rs6759518 0.655 rs2580382 chr2:27406555 A/G cg26210250 chr2:26863503 CIB4 -0.78 -4.46 -0.37 1.79e-5 Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs11190604 0.945 rs7091356 chr10:102292268 G/C cg16342193 chr10:102329863 NA -0.41 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9650657 0.740 rs10481451 chr8:10649328 A/G cg27411982 chr8:10470053 RP1L1 -0.22 -5.02 -0.41 1.75e-6 Neuroticism; TGCT cis rs1005277 0.505 rs200936 chr10:38134935 T/C cg13531842 chr10:38383804 ZNF37A -0.39 -4.58 -0.38 1.1e-5 Extrinsic epigenetic age acceleration; TGCT cis rs593531 0.571 rs6592557 chr11:74086642 T/C cg25592907 chr11:73676012 DNAJB13 0.33 4.81 0.4 4.23e-6 Neuroticism; TGCT cis rs12541335 0.639 rs11135995 chr8:22200148 C/T cg02463440 chr8:22132932 PIWIL2 -0.25 -4.96 -0.41 2.23e-6 Hypertriglyceridemia; TGCT cis rs10892173 0.782 rs6421566 chr11:117671398 G/A cg07621104 chr11:117668040 DSCAML1 0.51 5.38 0.43 3.59e-7 Myopia; TGCT cis rs3733585 0.605 rs7656624 chr4:10121097 T/C cg00071950 chr4:10020882 SLC2A9 -0.5 -5.35 -0.43 4.07e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs17376456 0.877 rs28633397 chr5:93447048 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs7193541 0.694 rs8061942 chr16:74691362 C/T cg01733217 chr16:74700730 RFWD3 1.01 13.54 0.77 3.37e-26 Multiple myeloma; TGCT cis rs7267979 0.706 rs6138542 chr20:25207773 C/A cg03522245 chr20:25566470 NINL 0.6 6.54 0.51 1.48e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3849570 1.000 rs6548773 chr3:81840222 C/T cg07356753 chr3:81810745 GBE1 0.82 7.62 0.56 5.6e-12 Waist circumference;Body mass index; TGCT cis rs16866061 0.515 rs11695326 chr2:225415134 A/G cg12698349 chr2:225449008 CUL3 1.12 15.51 0.81 8.08e-31 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs11785400 0.793 rs4567014 chr8:143737690 G/C cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs12497850 0.829 rs12636030 chr3:49182237 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.4 0.44 3.31e-7 Parkinson's disease; TGCT cis rs10791323 0.654 rs2851119 chr11:133706382 T/C cg03690763 chr11:133734501 NA -0.3 -4.73 -0.39 6.04e-6 Childhood ear infection; TGCT cis rs4242434 0.927 rs11136092 chr8:22466488 T/G cg03733263 chr8:22462867 KIAA1967 1.14 20.27 0.88 3.6e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs6570726 0.935 rs384519 chr6:145846017 C/A cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg21237687 chr17:6899380 ALOX12 0.54 5.72 0.46 7.41e-8 Tonsillectomy; TGCT cis rs10193935 0.901 rs6544529 chr2:42510652 A/T cg27598129 chr2:42591480 NA -0.42 -5.68 -0.45 9.05e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4242434 0.892 rs71513892 chr8:22456517 C/G cg03733263 chr8:22462867 KIAA1967 1.13 18.46 0.86 2.23e-37 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs12210905 0.920 rs72839468 chr6:27301734 A/G cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs317689 0.876 rs547332 chr12:69743639 C/G cg20891283 chr12:69753455 YEATS4 0.63 5.47 0.44 2.42e-7 Response to diuretic therapy; TGCT cis rs12478296 1.000 rs56292923 chr2:243039986 C/T cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs9633740 1.000 rs1870137 chr10:82269848 C/G cg01528321 chr10:82214614 TSPAN14 1.03 8.28 0.6 1.66e-13 Post bronchodilator FEV1; TGCT cis rs916888 0.647 rs199523 chr17:44848517 C/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.6 -4.63 -0.38 9.07e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs9303401 1.000 rs9303401 chr17:56847945 C/T cg12560992 chr17:57184187 TRIM37 0.53 5.44 0.44 2.71e-7 Cognitive test performance; TGCT cis rs7726839 0.574 rs11739866 chr5:636299 C/T cg20362242 chr5:692897 TPPP 0.52 4.65 0.39 8.29e-6 Obesity-related traits; TGCT cis rs2688608 0.653 rs12775558 chr10:75570868 G/A cg19442545 chr10:75533431 FUT11 -0.36 -5.7 -0.46 8.14e-8 Inflammatory bowel disease; TGCT cis rs4499344 0.633 rs259271 chr19:33157100 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs2070488 0.775 rs6780349 chr3:38555178 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.65 -5.88 -0.47 3.59e-8 Electrocardiographic conduction measures; TGCT cis rs9926296 0.533 rs10852623 chr16:89865242 T/C cg04287289 chr16:89883240 FANCA 0.93 12.26 0.74 4.13e-23 Vitiligo; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg23205692 chr1:25664452 TMEM50A 0.53 5.47 0.44 2.41e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs698813 0.604 rs1596009 chr2:44492102 G/T cg00619915 chr2:44497795 NA -0.24 -5.5 -0.44 2.05e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT trans rs3780486 0.846 rs10758192 chr9:33131651 G/A cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs826838 1.000 rs1393537 chr12:38920961 C/T cg26384229 chr12:38710491 ALG10B 1.01 9.79 0.66 4.11e-17 Heart rate; TGCT cis rs1550582 0.511 rs28673296 chr8:135474441 G/A cg17885191 chr8:135476712 NA 0.52 5.11 0.42 1.2e-6 Educational attainment; TGCT cis rs3733585 0.699 rs6449158 chr4:9960459 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.58 -0.51 1.2e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7959452 0.718 rs10878963 chr12:69717166 T/G cg20891283 chr12:69753455 YEATS4 0.51 4.77 0.39 4.98e-6 Blood protein levels; TGCT cis rs6598955 0.756 rs10902723 chr1:26568542 T/C cg04990556 chr1:26633338 UBXN11 -0.89 -11.39 -0.71 5.27e-21 Obesity-related traits; TGCT cis rs2274471 0.680 rs10974996 chr9:5192082 C/G cg03390472 chr9:5043263 JAK2 0.31 4.49 0.37 1.62e-5 Crohn's disease; TGCT cis rs933688 1.000 rs1035477 chr5:90743325 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.47 0.61 6.09e-14 Smoking behavior; TGCT cis rs2836974 0.829 rs8128191 chr21:40527311 A/G cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs9733 0.596 rs2065900 chr1:150652202 A/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg05665937 chr4:1216051 CTBP1 0.25 4.75 0.39 5.64e-6 Obesity-related traits; TGCT cis rs453301 0.658 rs12114954 chr8:8904862 T/G cg08975724 chr8:8085496 FLJ10661 -0.54 -4.46 -0.37 1.8e-5 Joint mobility (Beighton score); TGCT cis rs13191362 1.000 rs36007635 chr6:163009335 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1878931 0.545 rs28603 chr16:3449479 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.67 -5.31 -0.43 4.95e-7 Body mass index (adult); TGCT cis rs4654899 0.743 rs17409373 chr1:21188871 C/A cg01072550 chr1:21505969 NA -0.47 -7.09 -0.54 8.84e-11 Superior frontal gyrus grey matter volume; TGCT cis rs7727544 0.735 rs4705933 chr5:131678412 G/A cg24060327 chr5:131705240 SLC22A5 -0.56 -6.26 -0.49 5.61e-9 Blood metabolite levels; TGCT cis rs9814567 0.806 rs4245903 chr3:134317074 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.74 -6.96 -0.53 1.72e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3796619 1.000 rs11247973 chr4:1094314 G/A cg27284194 chr4:1044797 NA 0.46 4.5 0.37 1.56e-5 Recombination rate (males); TGCT cis rs5417 1.000 rs5418 chr17:7185092 G/A cg25256661 chr17:7137939 DVL2 -0.53 -4.97 -0.41 2.13e-6 Diastolic blood pressure; TGCT cis rs10791097 0.694 rs7942621 chr11:130751308 C/G cg12179176 chr11:130786555 SNX19 0.82 10.15 0.67 5.45e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3749237 0.595 rs7643845 chr3:49530711 A/G cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs1023500 0.596 rs5751209 chr22:42451603 A/G cg15557168 chr22:42548783 NA -0.19 -4.84 -0.4 3.73e-6 Schizophrenia; TGCT cis rs12579753 1.000 rs34031374 chr12:82235615 G/C cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs7714584 1.000 rs11167518 chr5:150258920 C/A cg22134413 chr5:150180641 NA 0.74 5.42 0.44 2.97e-7 Crohn's disease; TGCT cis rs11690935 0.632 rs17581284 chr2:172659376 C/T cg13550731 chr2:172543902 DYNC1I2 0.68 5.97 0.47 2.38e-8 Schizophrenia; TGCT cis rs514406 0.644 rs4926928 chr1:53210163 G/T cg08859206 chr1:53392774 SCP2 -0.35 -5.01 -0.41 1.84e-6 Monocyte count; TGCT cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.79 -0.52 4.07e-10 Initial pursuit acceleration; TGCT cis rs10465746 0.780 rs11163867 chr1:84384847 C/T cg10977910 chr1:84465055 TTLL7 0.71 7.15 0.54 6.64e-11 Obesity-related traits; TGCT cis rs727563 0.635 rs5751141 chr22:42107745 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.14 0.42 1.06e-6 Crohn's disease;Inflammatory bowel disease; TGCT trans rs6089829 0.925 rs6122086 chr20:61664528 T/C cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs6815814 0.950 rs4540055 chr4:38803255 A/T cg02016764 chr4:38805732 TLR1 -0.31 -5.18 -0.42 8.67e-7 Breast cancer; TGCT cis rs17125944 0.505 rs74620173 chr14:53194068 G/T cg00686598 chr14:53173677 PSMC6 1.19 6.34 0.49 3.96e-9 Alzheimer's disease (late onset); TGCT cis rs7267979 1.000 rs2257985 chr20:25269743 G/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg07092213 chr7:1199455 ZFAND2A -0.41 -4.46 -0.37 1.82e-5 Longevity;Endometriosis; TGCT cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg17971929 chr21:40555470 PSMG1 -0.73 -6.7 -0.52 6.49e-10 Cognitive function; TGCT cis rs6570726 0.577 rs403345 chr6:145845171 T/C cg23711669 chr6:146136114 FBXO30 0.7 6.39 0.5 3.12e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4919669 0.668 rs10883757 chr10:104400133 C/T cg05855489 chr10:104503620 C10orf26 0.73 4.51 0.38 1.47e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs7043114 0.525 rs1133908 chr9:95068046 C/T cg14631576 chr9:95140430 CENPP -0.28 -4.65 -0.39 8.23e-6 Height; TGCT cis rs7666738 0.784 rs4699602 chr4:99034903 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.5 0.56 1.06e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2836950 0.545 rs11701805 chr21:40618683 T/C cg11890956 chr21:40555474 PSMG1 -0.71 -6.95 -0.53 1.88e-10 Menarche (age at onset); TGCT cis rs6952808 0.529 rs73038442 chr7:2139457 C/T cg22963979 chr7:1858916 MAD1L1 -0.4 -6.44 -0.5 2.44e-9 Bipolar disorder and schizophrenia; TGCT cis rs782590 0.967 rs17278044 chr2:55748217 G/C cg18811423 chr2:55921094 PNPT1 0.67 7.1 0.54 8.6e-11 Metabolic syndrome; TGCT cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg07424592 chr7:64974309 NA -0.66 -6.62 -0.51 9.9e-10 Calcium levels; TGCT cis rs617219 0.671 rs2591392 chr5:78546293 G/A cg23514016 chr5:78407564 BHMT 0.34 5.05 0.41 1.51e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg01802117 chr1:53393560 SCP2 0.47 5.77 0.46 5.88e-8 Monocyte count; TGCT cis rs1729951 0.575 rs1682333 chr3:136688618 G/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs4604732 0.574 rs111928142 chr1:247625229 G/T cg22475246 chr1:246888027 SCCPDH 0.66 4.57 0.38 1.16e-5 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); TGCT cis rs2832191 0.679 rs2705659 chr21:30363908 G/C cg24692254 chr21:30365293 RNF160 0.96 11.17 0.71 1.77e-20 Dental caries; TGCT cis rs8072100 0.807 rs2175290 chr17:45479917 C/A cg08085267 chr17:45401833 C17orf57 -0.51 -5.71 -0.46 8.06e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9611565 0.659 rs116959331 chr22:41932774 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs1218582 0.772 rs10908445 chr1:154849590 A/G cg16680214 chr1:154839983 KCNN3 0.36 8.01 0.58 7.02e-13 Prostate cancer; TGCT cis rs5769765 0.657 rs8136116 chr22:50256886 T/A cg22709217 chr22:50311962 ALG12;CRELD2 1.0 6.16 0.48 9.32e-9 Schizophrenia; TGCT cis rs6951245 1.000 rs884977 chr7:1066410 T/C cg03188948 chr7:1209495 NA 0.58 4.69 0.39 6.95e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1218582 0.741 rs883718 chr1:154846274 C/T cg09359103 chr1:154839909 KCNN3 -0.67 -13.39 -0.77 7.55e-26 Prostate cancer; TGCT cis rs7772486 0.875 rs9322045 chr6:146384950 C/G cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.33e-9 Electroencephalogram traits; TGCT cis rs3752962 0.630 rs6503188 chr17:1950408 G/T cg24156229 chr17:1948635 NA -0.39 -7.56 -0.56 7.6e-12 Itch intensity from mosquito bite; TGCT cis rs2019137 0.936 rs12612729 chr2:113957048 G/A cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs377070 0.934 rs309392 chr4:123611542 G/T cg10495464 chr4:123653540 BBS12;LOC729338 0.46 5.16 0.42 9.5e-7 Mosquito bite size; TGCT cis rs6671200 0.607 rs2147587 chr1:95714884 G/A cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs1008375 0.932 rs6449315 chr4:17590219 A/G cg18681998 chr4:17616180 MED28 0.85 8.18 0.59 2.86e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12580194 0.593 rs61957938 chr12:55747266 C/G cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs344364 0.511 rs1742463 chr16:1946110 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9911578 1.000 rs11869828 chr17:56609525 G/A cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs367943 1.000 rs348956 chr5:112821464 C/T cg12552261 chr5:112820674 MCC 0.24 4.91 0.4 2.81e-6 Type 2 diabetes; TGCT cis rs2201728 0.967 rs4147531 chr4:100212197 G/A cg07219303 chr4:100140905 ADH6 -0.36 -5.27 -0.43 5.9e-7 Cardiac Troponin-T levels; TGCT cis rs1862618 0.620 rs189695 chr5:56225769 T/C cg20203395 chr5:56204925 C5orf35 -0.53 -4.92 -0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs7772486 0.790 rs9497431 chr6:146248177 T/C cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836950 0.545 rs2836959 chr21:40623668 T/G cg11644478 chr21:40555479 PSMG1 -0.52 -4.79 -0.4 4.59e-6 Menarche (age at onset); TGCT cis rs2820315 0.965 rs8028 chr1:201865763 A/G cg12730843 chr1:201915899 LMOD1 0.27 4.81 0.4 4.25e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs7811142 0.667 rs3873746 chr7:99935097 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.89 7.26 0.55 3.81e-11 Platelet count; TGCT trans rs561341 0.941 rs736678 chr17:30347423 G/T cg20587970 chr11:113659929 NA -1.05 -13.49 -0.77 4.42e-26 Hip circumference adjusted for BMI; TGCT cis rs7267979 0.934 rs2257464 chr20:25265872 C/T cg14121845 chr20:25566513 NINL 0.5 5.39 0.44 3.4e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9653442 0.500 rs72819191 chr2:100826572 A/G cg07810366 chr2:100720526 AFF3 0.39 5.33 0.43 4.39e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4819052 0.851 rs4819043 chr21:46660078 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.62 5.22 0.42 7.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2224391 0.704 rs17139985 chr6:5261603 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.8 -6.12 -0.48 1.13e-8 Height; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg06753367 chr22:24256600 NA -0.25 -4.73 -0.39 5.98e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs769267 0.965 rs2074299 chr19:19380646 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs2637266 0.678 rs846612 chr10:78550680 T/C cg18941641 chr10:78392320 NA 0.39 4.66 0.39 7.93e-6 Pulmonary function; TGCT cis rs7119 0.717 rs11631274 chr15:77816431 A/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs2932538 0.922 rs36029940 chr1:113106444 T/G cg22162597 chr1:113214053 CAPZA1 0.28 5.83 0.46 4.4e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs68170813 0.559 rs77013162 chr7:107071674 A/C cg02696742 chr7:106810147 HBP1 -0.7 -5.59 -0.45 1.41e-7 Coronary artery disease; TGCT cis rs2116941 0.523 rs17000211 chr19:10369086 C/T cg01850179 chr19:10340795 S1PR2 0.53 6.62 0.51 9.76e-10 Pulse pressure; TGCT cis rs5769765 0.955 rs8135816 chr22:50291976 G/C cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.91 0.47 3.12e-8 Schizophrenia; TGCT cis rs2760061 0.545 rs1745423 chr1:228224153 G/T cg18477163 chr1:228402036 OBSCN -0.32 -6.75 -0.52 5.11e-10 Diastolic blood pressure; TGCT cis rs1215050 0.791 rs165239 chr4:98682549 C/T cg05340658 chr4:99064831 C4orf37 0.43 5.4 0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9902453 1.000 rs57411618 chr17:28273052 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 7.0 0.53 1.44e-10 Coffee consumption (cups per day); TGCT cis rs2370759 1.000 rs76998371 chr10:32631785 A/G cg01819863 chr10:32635814 EPC1 1.0 9.52 0.65 1.8e-16 Sexual dysfunction (female); TGCT cis rs9581857 0.685 rs12585587 chr13:28024694 G/A cg22138327 chr13:27999177 GTF3A 0.7 5.01 0.41 1.85e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs57994353 0.600 rs13295852 chr9:139308426 G/A cg13741927 chr9:139327495 INPP5E -0.25 -5.54 -0.45 1.71e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs3858526 0.883 rs10769326 chr11:5934358 C/T cg13902645 chr11:5959945 NA -0.44 -4.64 -0.38 8.75e-6 DNA methylation (variation); TGCT cis rs34638657 0.732 rs11859473 chr16:82201072 T/C cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs9341808 0.667 rs7745301 chr6:80922561 G/T cg08355045 chr6:80787529 NA 0.29 4.88 0.4 3.2e-6 Sitting height ratio; TGCT cis rs797680 0.856 rs693737 chr1:93724924 G/A cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6088580 0.608 rs8114616 chr20:32969092 G/T cg06115741 chr20:33292138 TP53INP2 -0.51 -4.56 -0.38 1.2e-5 Glomerular filtration rate (creatinine); TGCT cis rs9916302 0.904 rs3744348 chr17:37417575 C/G cg07936489 chr17:37558343 FBXL20 -0.63 -4.99 -0.41 2.03e-6 Glomerular filtration rate (creatinine); TGCT cis rs597539 0.652 rs636049 chr11:68667198 A/C cg06028808 chr11:68637592 NA 0.52 6.79 0.52 4.1e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2730245 0.527 rs2709858 chr7:158675266 C/G cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs2562456 0.876 rs2681395 chr19:21738140 T/C cg01304269 chr19:21688519 ZNF429 0.57 4.74 0.39 5.86e-6 Pain; TGCT cis rs17221829 0.549 rs72969202 chr11:89358355 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg02073558 chr3:44770973 ZNF501 0.61 5.91 0.47 3.02e-8 Depressive symptoms; TGCT cis rs1008375 0.866 rs2109518 chr4:17572162 G/A cg18681998 chr4:17616180 MED28 0.93 9.36 0.64 4.4e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs826838 0.868 rs12322306 chr12:39130021 A/G cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT trans rs1814175 0.676 rs1721999 chr11:49917372 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs10504229 0.679 rs72649120 chr8:58040308 C/T cg08280861 chr8:58055591 NA 0.35 4.94 0.41 2.49e-6 Developmental language disorder (linguistic errors); TGCT cis rs1580019 0.587 rs9638880 chr7:32552401 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.1 0.78 1.55e-27 Cognitive ability; TGCT cis rs9926296 0.605 rs12709094 chr16:89853017 A/G cg27121462 chr16:89883253 FANCA 0.81 8.95 0.63 4.42e-15 Vitiligo; TGCT trans rs2727020 0.688 rs11040338 chr11:49360601 A/G cg15704280 chr7:45808275 SEPT13 0.72 8.33 0.6 1.26e-13 Coronary artery disease; TGCT cis rs1008375 0.966 rs3775927 chr4:17599894 G/T cg10189774 chr4:17578691 LAP3 0.61 5.35 0.43 4.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10744422 1.000 rs7138398 chr12:123341833 G/C cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs911263 0.603 rs1956524 chr14:68800393 G/A cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs854765 0.964 rs854810 chr17:18006421 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.65 -6.31 -0.49 4.57e-9 Total body bone mineral density; TGCT cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.96 0.41 2.28e-6 Height; TGCT cis rs1008375 1.000 rs10032326 chr4:17630717 A/T cg16339924 chr4:17578868 LAP3 0.62 5.11 0.42 1.21e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg11644478 chr21:40555479 PSMG1 0.97 10.46 0.68 9.69e-19 Cognitive function; TGCT cis rs2153535 0.580 rs2152348 chr6:8474301 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6500602 0.647 rs4786514 chr16:4576798 A/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.85 0.58 1.7e-12 Schizophrenia; TGCT cis rs250677 0.524 rs417413 chr5:148452726 T/C cg18129178 chr5:148520854 ABLIM3 -0.36 -5.32 -0.43 4.66e-7 Breast cancer; TGCT cis rs11690462 0.963 rs7602910 chr2:26619131 G/T cg04726446 chr2:26624865 C2orf39 0.42 4.63 0.38 9.27e-6 Coronary artery disease; TGCT cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg20887711 chr4:1340912 KIAA1530 0.94 7.81 0.57 2.1e-12 Longevity; TGCT cis rs7439150 1.000 rs2227407 chr4:155487984 C/T cg22130008 chr4:155548532 NA -0.48 -5.99 -0.47 2.07e-8 Fibrinogen levels; TGCT cis rs78487399 0.808 rs75126888 chr2:43664007 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4906332 1.000 rs35224956 chr14:103900481 A/G cg26031613 chr14:104095156 KLC1 -0.52 -4.59 -0.38 1.08e-5 Coronary artery disease; TGCT cis rs9611565 0.512 rs1983576 chr22:42166486 G/A cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg26354017 chr1:205819088 PM20D1 0.68 9.51 0.65 2e-16 Menarche (age at onset); TGCT cis rs7216064 1.000 rs1976054 chr17:65833224 T/G cg12091567 chr17:66097778 LOC651250 -0.87 -6.76 -0.52 4.7e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1971762 0.730 rs7963016 chr12:54072819 T/A cg09709951 chr12:54017699 ATF7 0.35 5.38 0.44 3.52e-7 Height; TGCT cis rs7917772 0.545 rs10786681 chr10:104317357 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7829975 0.509 rs2945269 chr8:8115578 G/C cg06636001 chr8:8085503 FLJ10661 0.82 8.2 0.59 2.55e-13 Mood instability; TGCT cis rs631288 0.557 rs2354434 chr1:146679428 A/G cg25205988 chr1:146714368 CHD1L 1.33 5.42 0.44 2.97e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.862 rs12698521 chr7:65939489 T/C cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.12e-6 Aortic root size; TGCT cis rs10191773 0.522 rs6747639 chr2:112967458 C/T cg07905836 chr2:113190072 RGPD8;RGPD5 0.43 4.44 0.37 1.96e-5 Yeast infection; TGCT cis rs10883723 0.810 rs7074343 chr10:104283165 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg03303774 chr4:1407052 NA -0.33 -4.94 -0.41 2.51e-6 Obesity-related traits; TGCT cis rs877282 0.945 rs11253388 chr10:787852 A/G cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT trans rs77457752 0.562 rs7874765 chr9:13899199 G/C cg23609682 chr1:3070786 PRDM16 0.5 6.79 0.52 4.09e-10 Breast cancer; TGCT cis rs28595532 0.920 rs115576008 chr4:119736967 T/C cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs4478858 0.735 rs1566961 chr1:31772450 G/A cg00250761 chr1:31883323 NA -0.28 -5.01 -0.41 1.86e-6 Alcohol dependence; TGCT cis rs2797160 1.000 rs2747720 chr6:126009458 A/G cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs4381823 0.850 rs116282013 chr2:48160511 G/A cg16590546 chr2:47169188 MCFD2;TTC7A -1.13 -4.49 -0.37 1.61e-5 Schizophrenia; TGCT cis rs9325144 0.600 rs6582630 chr12:38743508 A/G cg26384229 chr12:38710491 ALG10B -0.61 -5.6 -0.45 1.32e-7 Morning vs. evening chronotype; TGCT cis rs909002 0.789 rs56074668 chr1:32123801 T/C cg11573219 chr1:32083031 HCRTR1 -0.44 -5.61 -0.45 1.25e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg13695892 chr22:41940480 POLR3H -0.87 -8.01 -0.58 6.94e-13 Vitiligo; TGCT cis rs45535039 0.506 rs4936467 chr11:119086629 A/T cg16724696 chr11:118992527 HINFP -0.66 -6.47 -0.5 2.03e-9 Plateletcrit; TGCT cis rs7809950 0.678 rs6949634 chr7:106984684 G/T cg23024343 chr7:107201750 COG5 -0.44 -5.94 -0.47 2.66e-8 Coronary artery disease; TGCT cis rs7017914 0.905 rs4571761 chr8:71957173 A/C cg23757474 chr8:71581111 LACTB2;XKR9 0.55 5.11 0.42 1.17e-6 Bone mineral density; TGCT cis rs2228479 0.850 rs2190808 chr16:89840856 C/T cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs2439831 0.867 rs2243434 chr15:43689867 A/T cg27015174 chr15:43622946 ADAL;LCMT2 0.88 6.11 0.48 1.19e-8 Lung cancer in ever smokers; TGCT cis rs12477438 0.520 rs6739579 chr2:99731552 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs2456568 0.771 rs2102333 chr11:93634749 G/A cg14065697 chr11:93583672 C11orf90 -0.37 -4.63 -0.38 9.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs8032315 0.965 rs4932373 chr15:91429287 A/C cg03209642 chr15:91427605 FES 0.55 5.31 0.43 4.79e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs644799 0.648 rs1255182 chr11:95472391 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.55 5.61 0.45 1.23e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7945705 0.811 rs7119939 chr11:8861543 G/T cg21881798 chr11:8931708 C11orf17;ST5 0.41 4.56 0.38 1.23e-5 Hemoglobin concentration; TGCT cis rs9790314 0.846 rs6768818 chr3:160951648 A/G cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs2067615 0.560 rs12298717 chr12:107099883 C/T cg15890332 chr12:107067104 RFX4 -0.28 -5.87 -0.47 3.71e-8 Heart rate; TGCT cis rs9916302 0.904 rs8076494 chr17:37516722 A/G cg07936489 chr17:37558343 FBXL20 0.55 4.48 0.37 1.69e-5 Glomerular filtration rate (creatinine); TGCT cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.04 -0.67 9.96e-18 Bipolar disorder; TGCT trans rs7819412 0.511 rs35558344 chr8:11434232 C/T cg15556689 chr8:8085844 FLJ10661 -0.76 -7.1 -0.54 8.61e-11 Triglycerides; TGCT cis rs4906332 1.000 rs17617832 chr14:103943140 T/C cg26031613 chr14:104095156 KLC1 -0.52 -4.72 -0.39 6.31e-6 Coronary artery disease; TGCT cis rs4319547 0.956 rs7397990 chr12:123119472 T/C cg23029597 chr12:123009494 RSRC2 -0.28 -4.67 -0.39 7.68e-6 Body mass index; TGCT cis rs10256972 0.758 rs9801444 chr7:1080444 A/C cg03188948 chr7:1209495 NA -0.42 -5.24 -0.43 6.56e-7 Longevity;Endometriosis; TGCT cis rs6430585 0.528 rs16832440 chr2:136754183 G/A cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs12220238 0.822 rs2395087 chr10:76082637 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.28 0.49 5.18e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9399135 0.838 rs4896126 chr6:135342786 C/A cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs6558530 0.777 rs3812477 chr8:1734452 C/G cg09410841 chr8:1729607 CLN8 0.92 10.46 0.68 9.47e-19 Systolic blood pressure; TGCT cis rs2798269 0.604 rs2798277 chr13:22155781 C/G cg18095732 chr13:22033692 ZDHHC20 -0.52 -4.65 -0.39 8.43e-6 PR segment; TGCT cis rs12216125 0.801 rs56107510 chr6:25987436 C/A cg17691542 chr6:26056736 HIST1H1C 0.65 5.18 0.42 8.75e-7 Iron status biomarkers; TGCT cis rs9916302 0.752 rs11078895 chr17:37401051 A/G cg07936489 chr17:37558343 FBXL20 -0.77 -5.93 -0.47 2.85e-8 Glomerular filtration rate (creatinine); TGCT cis rs4820539 0.934 rs3788348 chr22:23467946 G/C cg21100191 chr22:23484243 RTDR1 0.88 10.0 0.67 1.28e-17 Bone mineral density; TGCT cis rs1915146 0.546 rs2681919 chr10:126859029 A/G cg23000734 chr10:126850823 CTBP2 0.46 4.95 0.41 2.35e-6 Menarche (age at onset); TGCT cis rs17125944 0.656 rs74825460 chr14:53390015 C/T cg00686598 chr14:53173677 PSMC6 0.92 4.54 0.38 1.29e-5 Alzheimer's disease (late onset); TGCT cis rs7572733 0.534 rs1435570 chr2:198731371 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs2458413 0.669 rs12681140 chr8:105346112 A/C cg13045555 chr8:105342365 NA 0.4 6.7 0.52 6.51e-10 Paget's disease; TGCT cis rs56235845 0.694 rs11749830 chr5:176766547 G/A cg06060754 chr5:176797920 RGS14 0.42 6.57 0.51 1.23e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg03404566 chr17:6899310 ALOX12 0.47 5.26 0.43 6.17e-7 Tonsillectomy; TGCT cis rs57221529 0.766 rs1399381 chr5:589853 G/T cg09021430 chr5:549028 NA -0.37 -4.98 -0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs9341808 0.727 rs1324120 chr6:80976125 G/C cg08355045 chr6:80787529 NA 0.29 4.98 0.41 2.04e-6 Sitting height ratio; TGCT cis rs6964587 1.000 rs9691325 chr7:91731047 G/A cg17063962 chr7:91808500 NA 0.88 9.61 0.65 1.13e-16 Breast cancer; TGCT cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg17554472 chr22:41940697 POLR3H -0.49 -5.26 -0.43 6.14e-7 Vitiligo; TGCT cis rs77669868 0.703 rs61904685 chr11:114072659 G/A cg01914181 chr11:114070210 ZBTB16 0.31 4.64 0.38 8.61e-6 Monocyte percentage of white cells; TGCT cis rs4819052 0.851 rs13047104 chr21:46673562 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs55883249 1.000 rs56372340 chr2:9741536 A/G cg23886495 chr2:9695866 ADAM17 0.82 5.01 0.41 1.86e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9303401 0.659 rs12946397 chr17:56769979 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs6912958 0.559 rs242279 chr6:88048191 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.72 7.53 0.56 9.05e-12 Monocyte percentage of white cells; TGCT cis rs7655441 0.964 rs7687679 chr4:80885183 G/A cg02241357 chr4:80885279 ANTXR2 -0.23 -4.52 -0.38 1.4e-5 Neutrophil percentage of white cells; TGCT cis rs10504229 0.595 rs79077737 chr8:58117520 G/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs7213347 0.581 rs4790881 chr17:2068932 C/A cg22033759 chr17:1182267 TUSC5 -0.23 -4.73 -0.39 5.94e-6 Total body bone mineral density; TGCT cis rs9902453 1.000 rs4239227 chr17:28389103 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs3008870 0.920 rs2755253 chr1:67470843 C/T cg02640540 chr1:67518911 SLC35D1 0.54 4.49 0.37 1.6e-5 Lymphocyte percentage of white cells; TGCT cis rs9549260 0.564 rs6563845 chr13:41318907 A/G cg21288729 chr13:41239152 FOXO1 0.95 9.29 0.64 6.71e-16 Red blood cell count; TGCT cis rs1964356 0.524 rs7839585 chr8:8854235 C/G cg08975724 chr8:8085496 FLJ10661 -0.54 -4.65 -0.39 8.26e-6 Mean corpuscular volume; TGCT cis rs6121246 0.909 rs6060923 chr20:30336655 A/C cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs10883723 0.810 rs10883728 chr10:104269301 A/G cg05855489 chr10:104503620 C10orf26 0.54 4.75 0.39 5.5e-6 Allergic disease (asthma, hay fever or eczema); TGCT trans rs114540395 0.858 rs77564076 chr10:103320818 C/A cg10198749 chr1:39920707 MACF1 0.55 7.05 0.53 1.11e-10 Schizophrenia; TGCT cis rs8072100 0.967 rs3760370 chr17:45695832 C/T cg08085267 chr17:45401833 C17orf57 0.43 4.63 0.38 9.02e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs3813567 0.759 rs12594550 chr15:78959037 C/G cg24631222 chr15:78858424 CHRNA5 -0.67 -4.65 -0.39 8.4e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs35306767 0.903 rs11253460 chr10:887382 C/G cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs9868809 0.881 rs3806694 chr3:48672334 G/C cg00383909 chr3:49044727 WDR6 0.97 5.08 0.42 1.34e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs12464483 0.591 rs4952171 chr2:30886903 G/A cg12454169 chr2:30669597 LCLAT1 0.5 5.27 0.43 5.97e-7 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs910316 1.000 rs12589376 chr14:75561152 C/T cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.81 5.23 0.42 7.13e-7 Platelet count; TGCT cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg17212791 chr22:49483368 NA 0.38 4.49 0.37 1.59e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs4074961 0.527 rs10908356 chr1:38038388 G/A cg11397548 chr1:38022522 DNALI1 0.42 4.83 0.4 3.93e-6 Axial length; TGCT cis rs12135062 0.851 rs2651925 chr1:3101863 C/G cg25382214 chr1:3105252 PRDM16 0.3 5.35 0.43 4.04e-7 Migraine; TGCT cis rs7824557 0.628 rs2572387 chr8:11204165 C/T cg21775007 chr8:11205619 TDH 0.74 7.15 0.54 6.66e-11 Retinal vascular caliber; TGCT cis rs15676 0.783 rs7858732 chr9:131563540 A/G cg00228799 chr9:131580591 ENDOG -0.55 -4.76 -0.39 5.19e-6 Blood metabolite levels; TGCT cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg20887711 chr4:1340912 KIAA1530 0.91 8.25 0.6 1.99e-13 Longevity; TGCT trans rs9951602 0.833 rs9953548 chr18:76640601 C/T cg02800362 chr5:177631904 HNRNPAB 0.99 7.18 0.54 5.69e-11 Obesity-related traits; TGCT cis rs7675861 1.000 rs11946892 chr4:5850377 T/A cg14241509 chr4:6196512 JAKMIP1 0.25 4.48 0.37 1.69e-5 Dysphagia; TGCT cis rs2153535 0.580 rs2327057 chr6:8443319 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg13683864 chr3:40499215 RPL14 -1.22 -13.35 -0.77 9.36e-26 Renal cell carcinoma; TGCT cis rs921968 0.509 rs3856548 chr2:219398164 C/T cg02176678 chr2:219576539 TTLL4 -0.49 -6.94 -0.53 1.95e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg03264133 chr6:25882463 NA -0.51 -5.27 -0.43 5.81e-7 Height; TGCT cis rs7027203 0.797 rs57882762 chr9:96580825 T/G cg14598338 chr9:96623480 NA -0.61 -9.39 -0.64 3.74e-16 DNA methylation (variation); TGCT cis rs7267979 1.000 rs2424716 chr20:25423538 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9902453 0.691 rs140701 chr17:28538532 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.62 5.91 0.47 3.02e-8 Coffee consumption (cups per day); TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg25767906 chr1:53392781 SCP2 -0.6 -7.71 -0.57 3.49e-12 Monocyte count; TGCT cis rs9300255 0.544 rs1716175 chr12:123658388 A/T cg00376283 chr12:123451042 ABCB9 0.74 5.74 0.46 6.97e-8 Neutrophil percentage of white cells; TGCT cis rs7973719 0.865 rs12830671 chr12:7347278 T/G cg07052231 chr12:7363540 PEX5 0.38 5.86 0.47 3.95e-8 IgG glycosylation; TGCT cis rs7267979 1.000 rs6083825 chr20:25366424 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17221829 0.965 rs10830355 chr11:89443429 C/T cg02982614 chr11:89391479 FOLH1B -0.27 -4.67 -0.39 7.67e-6 Anxiety in major depressive disorder; TGCT trans rs1005277 0.579 rs1740749 chr10:38521646 A/G cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg00024416 chr22:24240387 NA -0.24 -4.59 -0.38 1.06e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7959452 0.562 rs11177630 chr12:69767963 G/C cg11871910 chr12:69753446 YEATS4 0.82 8.82 0.62 8.61e-15 Blood protein levels; TGCT cis rs7552404 0.727 rs5745390 chr1:76306591 A/C cg03433033 chr1:76189801 ACADM 0.65 6.73 0.52 5.56e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9486719 0.948 rs2499813 chr6:96875338 T/C cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs713587 1.000 rs713587 chr2:25158281 C/T cg01884057 chr2:25150051 NA 0.39 8.05 0.59 5.76e-13 Body mass index in non-asthmatics; TGCT cis rs1577917 0.958 rs12196377 chr6:86566775 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -5.02 -0.41 1.74e-6 Response to antipsychotic treatment; TGCT cis rs67478160 0.572 rs8015603 chr14:104293678 C/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT trans rs1814175 0.817 rs10769617 chr11:49810421 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs644799 1.000 rs2508289 chr11:95624669 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.74 7.66 0.57 4.71e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.39e-10 Bipolar disorder; TGCT cis rs533581 0.866 rs562812 chr16:88970944 G/A cg16701003 chr16:89028210 CBFA2T3 0.41 5.3 0.43 5.11e-7 Social autistic-like traits; TGCT cis rs3812049 0.784 rs2568928 chr5:127487603 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.6 -5.47 -0.44 2.41e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs7772486 0.558 rs7753273 chr6:146066039 C/T cg23711669 chr6:146136114 FBXO30 -0.74 -6.63 -0.51 9.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg26818010 chr10:134567672 INPP5A -0.39 -5.52 -0.44 1.88e-7 Migraine; TGCT cis rs11718455 0.960 rs17076255 chr3:44002093 C/T cg08738300 chr3:44038990 NA 0.85 6.41 0.5 2.72e-9 Coronary artery disease; TGCT cis rs6681544 0.544 rs993099 chr1:82388902 G/A cg04226724 chr1:82268649 LPHN2 0.47 4.95 0.41 2.33e-6 Metabolite levels (X-11787); TGCT cis rs6952808 0.500 rs3823631 chr7:2190100 A/G cg22963979 chr7:1858916 MAD1L1 -0.38 -5.83 -0.46 4.5e-8 Bipolar disorder and schizophrenia; TGCT cis rs9308731 0.644 rs1837367 chr2:111874551 G/A cg04202892 chr2:111875749 ACOXL 0.54 6.22 0.49 6.96e-9 Chronic lymphocytic leukemia; TGCT cis rs17376456 0.877 rs10044139 chr5:93407803 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs8056742 1.000 rs11648527 chr16:85093913 A/G cg00229868 chr16:85520891 NA 0.34 5.1 0.42 1.22e-6 Amyotrophic lateral sclerosis; TGCT cis rs2204008 0.652 rs11520002 chr12:38022179 G/T cg13010199 chr12:38710504 ALG10B 0.65 5.23 0.42 7.11e-7 Bladder cancer; TGCT cis rs763121 0.962 rs2071887 chr22:38879010 A/T cg06022373 chr22:39101656 GTPBP1 0.71 6.64 0.51 8.71e-10 Menopause (age at onset); TGCT cis rs9911578 0.757 rs8081906 chr17:56631907 A/T cg12560992 chr17:57184187 TRIM37 -0.72 -7.62 -0.56 5.74e-12 Intelligence (multi-trait analysis); TGCT cis rs8084125 0.832 rs884472 chr18:74946087 A/G cg05528293 chr18:74961138 GALR1 0.48 4.8 0.4 4.45e-6 Obesity-related traits; TGCT cis rs1577917 0.958 rs1591438 chr6:86525214 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.23 -0.43 7.01e-7 Response to antipsychotic treatment; TGCT cis rs7954584 0.504 rs10840633 chr12:122377511 A/T cg21171335 chr12:122356390 WDR66 0.68 6.7 0.52 6.4e-10 Mean corpuscular volume; TGCT cis rs1505368 0.567 rs972491 chr2:213316573 A/G cg20637307 chr2:213403960 ERBB4 -0.67 -7.06 -0.54 1.06e-10 Symmetrical dimethylarginine levels; TGCT cis rs2072499 1.000 rs2241108 chr1:156181007 C/G cg24450063 chr1:156163899 SLC25A44 1.17 17.17 0.84 1.46e-34 Testicular germ cell tumor; TGCT cis rs9649213 1.000 rs9649213 chr7:98021211 A/G cg09267113 chr7:98030324 BAIAP2L1 -0.66 -5.71 -0.46 7.97e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs11122272 0.735 rs2486741 chr1:231516450 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs250677 0.522 rs919731 chr5:148352150 T/C cg18129178 chr5:148520854 ABLIM3 0.38 4.88 0.4 3.23e-6 Breast cancer; TGCT cis rs308403 0.509 rs309376 chr4:123680191 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.69 0.72 9.78e-22 Blood protein levels; TGCT cis rs3125734 0.571 rs7100401 chr10:64024417 C/G cg09941381 chr10:64027924 RTKN2 -0.37 -5.64 -0.45 1.1e-7 Rheumatoid arthritis; TGCT cis rs2014511 1.000 rs6848819 chr4:154451678 A/C cg17385088 chr4:153611560 NA -0.45 -5.01 -0.41 1.83e-6 Platelet distribution width;Mean platelet volume; TGCT cis rs8016982 0.962 rs8007841 chr14:81647878 C/T cg01989461 chr14:81687754 GTF2A1 -0.61 -5.09 -0.42 1.29e-6 Schizophrenia; TGCT cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Vitiligo; TGCT cis rs9443645 0.808 rs2050661 chr6:79661125 T/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs9972944 0.729 rs7502798 chr17:63781615 C/T cg07283582 chr17:63770753 CCDC46 0.25 4.8 0.4 4.39e-6 Total body bone mineral density; TGCT cis rs116161686 0.500 rs76610459 chr1:210050756 T/G cg04352962 chr1:209979756 IRF6 0.63 4.48 0.37 1.65e-5 Coronary artery disease; TGCT cis rs12464483 0.524 rs2256411 chr2:30886860 C/A cg17749961 chr2:30669863 LCLAT1 0.58 4.5 0.37 1.55e-5 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs9443645 0.901 rs3805747 chr6:79672522 A/G cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs7803454 chr7:99991548 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT trans rs931812 0.757 rs35569317 chr8:101907971 T/C cg20993868 chr7:22813445 NA 0.32 6.63 0.51 9.13e-10 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs1215050 0.791 rs684210 chr4:98678740 G/C cg17366294 chr4:99064904 C4orf37 0.52 5.51 0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7833790 0.636 rs12544174 chr8:82731477 G/A cg06027949 chr8:82754900 SNX16 -0.65 -5.03 -0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs7945705 0.935 rs1883098 chr11:8890594 G/A cg21881798 chr11:8931708 C11orf17;ST5 -0.48 -5.46 -0.44 2.51e-7 Hemoglobin concentration; TGCT cis rs3820928 0.874 rs1996998 chr2:227840294 C/A cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs12142240 0.698 rs17361805 chr1:46813967 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.75 -0.39 5.54e-6 Menopause (age at onset); TGCT cis rs9393777 0.513 rs13195210 chr6:26646521 C/T cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs10779751 0.960 rs4845857 chr1:11285680 T/C cg08854313 chr1:11322531 MTOR 0.96 10.15 0.67 5.52e-18 Body mass index; TGCT cis rs72945132 0.882 rs11235953 chr11:70184937 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs6690583 0.623 rs893618 chr1:85513770 C/T cg20280350 chr1:85513789 MCOLN3 -0.79 -4.9 -0.4 2.9e-6 Serum sulfate level; TGCT cis rs10242455 0.702 rs76840929 chr7:98945858 T/C cg13560068 chr7:99070416 ZNF789 1.1 4.68 0.39 7.38e-6 Blood metabolite levels; TGCT cis rs858239 0.600 rs2003555 chr7:23122915 C/T cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4713675 0.649 rs568901 chr6:33710038 A/G cg18005901 chr6:33739558 LEMD2 0.49 5.92 0.47 2.88e-8 Plateletcrit; TGCT cis rs9303401 0.538 rs12603174 chr17:56489279 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.6 5.61 0.45 1.23e-7 Cognitive test performance; TGCT cis rs3749237 0.595 rs3870338 chr3:49557051 A/G cg03060546 chr3:49711283 APEH 0.74 8.46 0.6 6.25e-14 Resting heart rate; TGCT cis rs3806843 0.966 rs2563260 chr5:140137867 C/A cg19875535 chr5:140030758 IK -0.37 -6.4 -0.5 2.86e-9 Depressive symptoms (multi-trait analysis); TGCT trans rs7726839 0.540 rs11739847 chr5:609661 G/A cg11887960 chr12:57824829 NA 1.2 9.35 0.64 4.8e-16 Obesity-related traits; TGCT cis rs9733 0.596 rs6686525 chr1:150635811 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT trans rs7698623 0.867 rs4693191 chr4:88797873 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs2228479 0.702 rs17233441 chr16:89817998 C/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs12220238 0.722 rs7901055 chr10:76415029 A/C cg19889307 chr10:75911429 ADK;AP3M1 -0.6 -4.62 -0.38 9.58e-6 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs28595532 0.841 rs55823625 chr4:119780600 T/A cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs9581857 0.547 rs9579086 chr13:28058537 T/A cg22138327 chr13:27999177 GTF3A 0.71 4.43 0.37 2.01e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7729723 0.533 rs6596433 chr5:137814972 G/A cg19169342 chr5:137827400 NA 0.33 4.6 0.38 1.04e-5 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs7726839 0.540 rs11750321 chr5:599196 C/T cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs2239547 0.522 rs7652131 chr3:52997154 C/T cg10802521 chr3:52805072 NEK4 -0.61 -5.9 -0.47 3.2e-8 Schizophrenia; TGCT cis rs17376456 0.877 rs12716456 chr5:93397557 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs4665809 0.652 rs4665832 chr2:26404775 A/G cg25036284 chr2:26402008 FAM59B -0.58 -4.61 -0.38 1.01e-5 Gut microbiome composition (summer); TGCT cis rs1218582 0.772 rs6683557 chr1:154852307 C/G cg03351412 chr1:154909251 PMVK 0.52 4.8 0.4 4.4e-6 Prostate cancer; TGCT cis rs7507204 0.906 rs11671513 chr19:3429937 C/T cg08380311 chr19:3435252 NFIC 0.95 8.01 0.58 7.03e-13 Height; TGCT cis rs1865760 1.000 rs2071301 chr6:25914263 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.3 0.49 4.62e-9 Height; TGCT cis rs7833790 0.724 rs72603871 chr8:82754460 C/G cg27398817 chr8:82754497 SNX16 0.69 5.52 0.44 1.9e-7 Diastolic blood pressure; TGCT cis rs9486715 0.867 rs9486444 chr6:96963619 A/G cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT trans rs74910095 0.656 rs11958312 chr5:62937589 G/A cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs12339966 0.653 rs11794038 chr9:11327731 C/A cg03488587 chr11:64876988 C11orf2 0.3 6.9 0.53 2.36e-10 Systolic blood pressure; TGCT cis rs5769707 1.000 rs5769707 chr22:50013402 G/T cg05373962 chr22:49881684 NA -0.3 -6.21 -0.49 7.34e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7772486 0.743 rs9390344 chr6:146012755 C/G cg05347473 chr6:146136440 FBXO30 -0.49 -4.67 -0.39 7.63e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.710 rs1532204 chr3:49609477 C/G cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs11098499 0.954 rs71614438 chr4:120371252 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7246657 1.000 rs6508710 chr19:37749886 A/G cg03233940 chr19:37894644 NA -0.37 -4.79 -0.39 4.73e-6 Coronary artery calcification; TGCT cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg11890956 chr21:40555474 PSMG1 1.1 12.16 0.74 7.11e-23 Cognitive function; TGCT cis rs7829975 0.540 rs2976909 chr8:8346690 C/T cg06636001 chr8:8085503 FLJ10661 -0.56 -5.48 -0.44 2.3e-7 Mood instability; TGCT cis rs7909074 0.798 rs914699 chr10:45377066 A/C cg04218760 chr10:45406644 TMEM72 -0.3 -5.92 -0.47 2.88e-8 Mean corpuscular volume; TGCT cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.68 -0.39 7.3e-6 Developmental language disorder (linguistic errors); TGCT cis rs1005224 0.963 rs12887886 chr14:76167846 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.63 -5.64 -0.45 1.09e-7 Large artery stroke; TGCT cis rs10782582 0.593 rs6704444 chr1:76205108 T/C cg10523679 chr1:76189770 ACADM -0.67 -6.75 -0.52 4.99e-10 Daytime sleep phenotypes; TGCT cis rs12681288 0.550 rs60530879 chr8:958381 G/C cg04851639 chr8:1020857 NA -0.27 -4.45 -0.37 1.85e-5 Schizophrenia; TGCT cis rs2013441 1.000 rs2013441 chr17:20023099 G/A cg23224458 chr17:20280056 CCDC144C 0.4 4.72 0.39 6.31e-6 Obesity-related traits; TGCT cis rs57590327 0.644 rs62265393 chr3:81526075 G/C cg07356753 chr3:81810745 GBE1 -0.53 -4.44 -0.37 1.97e-5 Extraversion; TGCT cis rs2836974 0.623 rs7280326 chr21:40700408 A/G cg17971929 chr21:40555470 PSMG1 -0.68 -5.96 -0.47 2.47e-8 Cognitive function; TGCT cis rs8111998 0.826 rs10420648 chr19:22767819 G/A cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs478304 0.593 rs7120713 chr11:65483374 G/C cg17480646 chr11:65405466 SIPA1 -0.59 -6.88 -0.53 2.63e-10 Acne (severe); TGCT cis rs2956278 0.717 rs2929750 chr12:84680334 G/A cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs55962025 0.804 rs3775061 chr4:3238754 A/G cg06533319 chr4:3265114 C4orf44 0.24 4.61 0.38 9.98e-6 Parental longevity (mother's age at death); TGCT cis rs6912958 1.000 rs6912958 chr6:88133315 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.68 -6.84 -0.52 3.18e-10 Monocyte percentage of white cells; TGCT cis rs4727027 0.801 rs12666337 chr7:148796253 C/T cg23583168 chr7:148888333 NA -0.72 -9.11 -0.63 1.8e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12497850 0.931 rs3774628 chr3:48801840 C/T cg05785598 chr3:49045655 WDR6 0.35 4.75 0.39 5.58e-6 Parkinson's disease; TGCT cis rs752010 0.714 rs10890144 chr1:42085397 G/T cg06885757 chr1:42089581 HIVEP3 0.24 4.58 0.38 1.12e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs9325144 0.625 rs12227353 chr12:38734542 C/T cg26384229 chr12:38710491 ALG10B -0.61 -5.58 -0.45 1.43e-7 Morning vs. evening chronotype; TGCT cis rs9788682 0.747 rs8043009 chr15:78908154 G/C cg24631222 chr15:78858424 CHRNA5 0.78 5.71 0.46 8.03e-8 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT trans rs8073060 0.586 rs226089 chr17:34016935 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6831352 0.918 rs17218288 chr4:100058030 A/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs3862435 0.572 rs2601165 chr15:90908934 C/G cg14166756 chr15:90894880 ZNF774 0.29 4.57 0.38 1.15e-5 Response to exercise (triglyceride level interaction); TGCT cis rs9486719 0.948 rs6920913 chr6:96874297 A/G cg18709589 chr6:96969512 KIAA0776 0.69 5.49 0.44 2.2e-7 Migraine;Coronary artery disease; TGCT cis rs3087591 0.592 rs2342054 chr17:29724708 G/A cg24425628 chr17:29625626 OMG;NF1 0.4 5.85 0.47 4.05e-8 Hip circumference; TGCT trans rs12339966 0.601 rs57645776 chr9:11290297 C/T cg03488587 chr11:64876988 C11orf2 0.3 6.7 0.52 6.5e-10 Systolic blood pressure; TGCT cis rs6964587 0.610 rs2888850 chr7:91430027 T/C cg17063962 chr7:91808500 NA 0.73 6.64 0.51 8.68e-10 Breast cancer; TGCT cis rs3540 0.960 rs8030299 chr15:91026459 G/A cg22089800 chr15:90895588 ZNF774 0.77 7.25 0.55 4.02e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs910316 1.000 rs4899546 chr14:75594946 G/C cg11812906 chr14:75593930 NEK9 0.74 7.37 0.55 2.12e-11 Height; TGCT cis rs7772486 0.790 rs1832362 chr6:146179955 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.61e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs921521 chr4:98838339 A/G cg05340658 chr4:99064831 C4orf37 0.52 6.05 0.48 1.61e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs981844 0.712 rs6855093 chr4:154754050 A/G cg14289246 chr4:154710475 SFRP2 -0.98 -8.82 -0.62 8.67e-15 Response to statins (LDL cholesterol change); TGCT cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg00786635 chr1:25594202 NA 0.54 5.52 0.44 1.93e-7 Erythrocyte sedimentation rate; TGCT cis rs7618915 0.501 rs3852066 chr3:52621839 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs2842992 0.789 rs4276525 chr6:160193612 G/A cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs2243480 1.000 rs6974723 chr7:65637939 C/T cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs79387448 0.745 rs6749440 chr2:103101846 C/T cg09003973 chr2:102972529 NA 0.88 5.86 0.47 3.87e-8 Gut microbiota (bacterial taxa); TGCT cis rs57920188 0.584 rs12128330 chr1:4092926 G/A cg20703997 chr1:4087676 NA 0.48 5.81 0.46 5e-8 Interleukin-17 levels; TGCT cis rs12142240 0.698 rs41294476 chr1:46818374 C/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs9399135 0.967 rs4896121 chr6:135293645 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.75 0.39 5.5e-6 Red blood cell count; TGCT cis rs3924048 0.547 rs6678689 chr1:12619904 A/G cg00291366 chr1:12616550 NA 0.34 5.06 0.41 1.47e-6 Optic cup area; TGCT cis rs9357506 1.000 rs1837898 chr6:46322410 A/G cg21115430 chr6:46460003 NA -0.23 -4.54 -0.38 1.34e-5 Body mass index; TGCT cis rs2963155 0.518 rs33389 chr5:142700499 C/T cg17617527 chr5:142782415 NR3C1 0.84 6.16 0.48 9.5e-9 Breast cancer; TGCT cis rs7267979 0.789 rs2260197 chr20:25284343 T/C cg16686733 chr20:25566563 NINL 0.49 4.62 0.38 9.44e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg00149659 chr3:10157352 C3orf10 -0.9 -6.17 -0.48 8.88e-9 Alzheimer's disease; TGCT cis rs7772486 0.754 rs6570703 chr6:145957052 C/T cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.07 0.41 1.4e-6 Platelet count; TGCT cis rs3733585 0.673 rs9994266 chr4:9954450 C/T cg11266682 chr4:10021025 SLC2A9 -0.55 -7.29 -0.55 3.2e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11096990 0.656 rs3733284 chr4:39301334 A/G cg20847110 chr4:39482781 LOC401127 -0.17 -4.82 -0.4 4.05e-6 Cognitive function; TGCT cis rs7635838 0.684 rs2606757 chr3:11358163 T/A cg00170343 chr3:11313890 ATG7 0.6 5.86 0.47 3.84e-8 HDL cholesterol; TGCT cis rs4862750 0.872 rs1991254 chr4:187875375 T/G cg10295955 chr4:187884368 NA -0.95 -14.1 -0.78 1.61e-27 Lobe attachment (rater-scored or self-reported); TGCT cis rs208520 0.874 rs208515 chr6:66945749 A/G cg07460842 chr6:66804631 NA -0.9 -9.15 -0.63 1.45e-15 Exhaled nitric oxide output; TGCT cis rs9467773 1.000 rs6933176 chr6:26540178 G/A cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs896854 0.818 rs13262110 chr8:95926890 C/T cg23172400 chr8:95962367 TP53INP1 -0.34 -5.51 -0.44 2.02e-7 Type 2 diabetes; TGCT cis rs3820068 0.603 rs6429753 chr1:15900537 A/G cg05660106 chr1:15850417 CASP9 1.11 13.25 0.77 1.63e-25 Systolic blood pressure; TGCT cis rs35146811 0.695 rs1727132 chr7:99812297 T/C cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs1218582 0.741 rs883718 chr1:154846274 C/T cg16680214 chr1:154839983 KCNN3 -0.38 -8.12 -0.59 4e-13 Prostate cancer; TGCT cis rs2708977 0.608 rs631033 chr2:97090430 C/T cg01950434 chr2:97203154 ARID5A -0.61 -5.26 -0.43 6.08e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1129187 0.702 rs2296805 chr6:42928758 T/G cg09436375 chr6:42928200 GNMT -0.43 -5.41 -0.44 3.13e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7635838 0.859 rs9875414 chr3:11453559 A/G cg00170343 chr3:11313890 ATG7 0.65 6.15 0.48 9.98e-9 HDL cholesterol; TGCT cis rs17345786 0.520 rs1476123 chr3:101313413 C/G cg12386194 chr3:101231763 SENP7 0.53 5.59 0.45 1.38e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.964 rs72827413 chr17:17988299 C/T cg04398451 chr17:18023971 MYO15A 0.3 4.67 0.39 7.55e-6 Total body bone mineral density; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg23131131 chr22:24373011 LOC391322 -0.8 -8.63 -0.61 2.53e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 1.000 rs35066600 chr4:98991066 C/A cg17366294 chr4:99064904 C4orf37 0.69 6.39 0.5 3.1e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg02953382 chr22:24373134 LOC391322 -0.57 -5.46 -0.44 2.44e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1205863 0.607 rs1205849 chr6:11940464 G/C cg07106625 chr6:11870215 NA 0.45 4.68 0.39 7.29e-6 Disc degeneration (lumbar); TGCT cis rs6940638 0.956 rs36048693 chr6:27032711 T/G cg16898833 chr6:26189333 HIST1H4D 0.72 5.39 0.44 3.37e-7 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs35146811 0.735 rs1637001 chr7:99808151 G/A cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs8141529 0.509 rs7287124 chr22:29239157 A/G cg02153584 chr22:29168773 CCDC117 0.64 5.25 0.43 6.31e-7 Lymphocyte counts; TGCT cis rs1056053 0.514 rs3127329 chr6:166572362 G/A cg17219086 chr6:166541254 NA -0.19 -4.5 -0.37 1.55e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs1401999 0.546 rs4148593 chr3:183649870 A/G cg01324343 chr3:183735012 ABCC5 0.56 6.19 0.49 8.13e-9 Anterior chamber depth; TGCT cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2880765 0.835 rs12910373 chr15:86046802 G/C cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs9486719 1.000 rs9373978 chr6:97056255 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.21 -0.59 2.44e-13 Migraine;Coronary artery disease; TGCT trans rs3780486 0.522 rs7029897 chr9:33124042 T/C cg20290983 chr6:43655470 MRPS18A 0.79 8.62 0.61 2.64e-14 IgG glycosylation; TGCT cis rs1023500 0.507 rs6002600 chr22:42488906 G/A cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Schizophrenia; TGCT cis rs9467773 0.873 rs9295698 chr6:26566099 T/A cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg09177884 chr7:1199841 ZFAND2A -0.53 -5.12 -0.42 1.11e-6 Longevity;Endometriosis; TGCT cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.54 -0.51 1.42e-9 Alzheimer's disease; TGCT trans rs9951602 0.512 rs4799244 chr18:76649763 T/C cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs17253792 0.822 rs79538158 chr14:56051365 G/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7829975 0.782 rs6990746 chr8:8547811 A/G cg06636001 chr8:8085503 FLJ10661 -0.6 -5.02 -0.41 1.77e-6 Mood instability; TGCT cis rs1008375 0.966 rs2315645 chr4:17579678 G/C cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs8177253 1.000 rs8177261 chr3:133480588 A/C cg08048268 chr3:133502702 NA -0.65 -9.83 -0.66 3.21e-17 Iron status biomarkers; TGCT cis rs986417 1.000 rs1254286 chr14:60858300 T/C cg27398547 chr14:60952738 C14orf39 -1.41 -9.11 -0.63 1.75e-15 Gut microbiota (bacterial taxa); TGCT cis rs4819052 0.851 rs13047104 chr21:46673562 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7208859 0.524 rs59923796 chr17:29064919 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg02953382 chr22:24373134 LOC391322 -0.85 -10.0 -0.67 1.28e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6460942 0.908 rs73677559 chr7:12270819 A/C cg06484146 chr7:12443880 VWDE -0.53 -4.65 -0.39 8.3e-6 Coronary artery disease; TGCT cis rs782590 0.902 rs2586947 chr2:55854009 C/G cg18811423 chr2:55921094 PNPT1 0.67 7.12 0.54 7.68e-11 Metabolic syndrome; TGCT cis rs3096299 0.685 rs12935112 chr16:89542858 C/T cg08392591 chr16:89556376 ANKRD11 -0.57 -5.42 -0.44 3.02e-7 Multiple myeloma (IgH translocation); TGCT cis rs7659604 0.676 rs6534323 chr4:122695888 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.41 -0.44 3.12e-7 Type 2 diabetes; TGCT trans rs916888 0.738 rs199515 chr17:44856641 C/G cg22433210 chr17:43662623 NA -0.97 -6.84 -0.52 3.24e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2708977 0.901 rs6753667 chr2:97160382 G/A cg01950434 chr2:97203154 ARID5A -0.66 -5.84 -0.46 4.34e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs4654899 0.758 rs1354792 chr1:21391875 C/T cg01072550 chr1:21505969 NA 0.57 9.25 0.64 8.18e-16 Superior frontal gyrus grey matter volume; TGCT trans rs7618501 0.602 rs2013208 chr3:50129399 C/T cg21659725 chr3:3221576 CRBN -0.73 -8.42 -0.6 7.67e-14 Intelligence (multi-trait analysis); TGCT cis rs10779751 1.000 rs2024627 chr1:11298790 T/C cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs9341808 0.690 rs9343970 chr6:80881289 C/G cg08355045 chr6:80787529 NA 0.32 5.64 0.45 1.11e-7 Sitting height ratio; TGCT cis rs9952991 0.883 rs2847293 chr18:12782448 A/T cg24737193 chr18:12778029 NA 0.53 5.93 0.47 2.8e-8 Inflammatory skin disease; TGCT cis rs7845219 0.544 rs7016078 chr8:95922615 G/A cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs9549367 0.789 rs6577035 chr13:113879997 G/A cg18105134 chr13:113819100 PROZ -0.33 -5.38 -0.43 3.61e-7 Platelet distribution width; TGCT cis rs7926906 1.000 rs7939348 chr11:90522401 T/A cg26138821 chr11:89956704 CHORDC1 -0.51 -5.52 -0.44 1.92e-7 Intelligence (multi-trait analysis); TGCT cis rs1055129 0.537 rs1135640 chr17:73949540 C/G cg02678768 chr17:74002944 EVPL -0.24 -4.54 -0.38 1.32e-5 White matter hyperintensity burden; TGCT cis rs9911578 0.967 rs8072712 chr17:57162464 A/T cg12560992 chr17:57184187 TRIM37 0.79 9.71 0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs8078723 1.000 rs1042658 chr17:38173902 C/T cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs2224391 0.628 rs2753245 chr6:5258092 G/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.95 -5.69 -0.46 8.51e-8 Height; TGCT cis rs28386778 0.897 rs8079818 chr17:61824667 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs56116382 0.604 rs9858428 chr3:49877585 G/T cg08550065 chr3:50336684 HYAL3;NAT6 1.03 4.99 0.41 1.95e-6 Intelligence (multi-trait analysis);High light scatter reticulocyte count; TGCT cis rs2594989 0.943 rs2594970 chr3:11400877 C/T cg00170343 chr3:11313890 ATG7 0.66 5.11 0.42 1.2e-6 Circulating chemerin levels; TGCT cis rs2228479 0.850 rs62054640 chr16:89823157 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs853679 0.567 rs9969098 chr6:28398748 G/T cg18815343 chr6:28367644 ZSCAN12 -0.5 -4.56 -0.38 1.19e-5 Depression; TGCT cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg11301795 chr4:187892539 NA -0.34 -4.9 -0.4 2.97e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg02073558 chr3:44770973 ZNF501 0.61 5.93 0.47 2.86e-8 Depressive symptoms; TGCT cis rs7432375 0.641 rs835649 chr3:136671890 G/A cg15507776 chr3:136538369 TMEM22 0.51 5.19 0.42 8.19e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs904251 0.772 rs1812186 chr6:37465916 T/C cg25019722 chr6:37503610 NA -0.43 -5.02 -0.41 1.76e-6 Cognitive performance; TGCT cis rs2299587 0.585 rs2073569 chr8:17782158 T/G cg01800426 chr8:17659068 MTUS1 -0.64 -5.52 -0.44 1.91e-7 Economic and political preferences; TGCT cis rs7714584 1.000 rs11739619 chr5:150264662 A/T cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs514475 0.526 rs12201430 chr6:137955515 G/A cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs7178424 0.711 rs3743297 chr15:62149784 T/C cg00456672 chr15:62358751 C2CD4A -0.33 -5.03 -0.41 1.71e-6 Height; TGCT cis rs11098499 0.754 rs1849457 chr4:120254355 A/G cg09307838 chr4:120376055 NA 0.61 5.81 0.46 5.04e-8 Corneal astigmatism; TGCT cis rs3617 0.652 rs60332615 chr3:52867595 C/A cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9411298 0.657 rs4880189 chr9:139923265 A/G cg14024893 chr9:139943146 ENTPD2 0.37 5.87 0.47 3.81e-8 Monocyte percentage of white cells; TGCT cis rs4566357 1.000 rs6721237 chr2:227923357 T/A cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg20007245 chr22:24372913 LOC391322 0.82 7.03 0.53 1.2e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs4699052 0.625 rs28397882 chr4:104282836 G/A cg16532752 chr4:104119610 CENPE -0.5 -4.75 -0.39 5.48e-6 Testicular germ cell tumor; TGCT cis rs4499344 0.730 rs377044 chr19:33105951 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.86 9.05 0.63 2.48e-15 Mean platelet volume; TGCT cis rs7432375 0.519 rs34799319 chr3:136586618 G/A cg12473912 chr3:136751656 NA 0.33 4.59 0.38 1.06e-5 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs12908161 0.959 rs62019472 chr15:85331493 A/G cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.1e-8 Schizophrenia; TGCT cis rs35306767 0.903 rs12260800 chr10:927933 T/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs7216064 1.000 rs11870068 chr17:65944515 A/C cg12091567 chr17:66097778 LOC651250 -0.82 -6.2 -0.49 7.54e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1949733 0.701 rs871768 chr4:8454938 G/A cg13073564 chr4:8508604 NA -0.42 -4.61 -0.38 9.77e-6 Response to antineoplastic agents; TGCT cis rs4237845 1.000 rs4237845 chr12:58302436 A/G cg02175503 chr12:58329896 NA -0.55 -5.86 -0.47 3.86e-8 Intelligence (multi-trait analysis); TGCT cis rs4700695 0.841 rs417074 chr5:65314894 C/T cg21114390 chr5:65439923 SFRS12 0.6 4.47 0.37 1.71e-5 Facial morphology (factor 19); TGCT cis rs7914558 0.966 rs10450373 chr10:104728616 T/C cg04362960 chr10:104952993 NT5C2 0.6 5.38 0.44 3.56e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg11965913 chr1:205819406 PM20D1 0.6 9.43 0.65 3.09e-16 Menarche (age at onset); TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg17345569 chr6:42928274 GNMT -0.47 -4.81 -0.4 4.25e-6 Plasma homocysteine levels (post-methionine load test); TGCT cis rs12135062 0.851 rs2651927 chr1:3101762 A/C cg25382214 chr1:3105252 PRDM16 -0.29 -5.09 -0.42 1.27e-6 Migraine; TGCT cis rs2130392 0.926 rs7680323 chr4:185652871 A/T cg14471096 chr4:185570637 CCDC111;CASP3 -0.52 -4.95 -0.41 2.33e-6 Kawasaki disease; TGCT cis rs10501293 0.746 rs7929118 chr11:43029294 C/T cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.14e-9 Cognitive performance; TGCT cis rs9322193 0.884 rs9688794 chr6:149953257 C/T cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs8072100 0.846 rs7214799 chr17:45702099 C/T cg08085267 chr17:45401833 C17orf57 0.44 4.68 0.39 7.52e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7954584 0.567 rs10840632 chr12:122375460 C/T cg21171335 chr12:122356390 WDR66 0.68 6.79 0.52 4.16e-10 Mean corpuscular volume; TGCT cis rs13223928 0.516 rs11763949 chr7:3150279 A/C cg19214707 chr7:3157722 NA -0.44 -6.2 -0.49 7.57e-9 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs7666738 0.791 rs13111960 chr4:98976851 C/T cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10507380 0.824 rs77045357 chr13:27925794 C/G cg25543773 chr13:27185723 WASF3 0.32 4.51 0.38 1.47e-5 Electrocardiographic traits; TGCT cis rs1669338 0.588 rs6784329 chr3:3200013 C/T cg16797762 chr3:3221439 CRBN -0.9 -5.72 -0.46 7.43e-8 White matter integrity; TGCT cis rs12682352 0.652 rs3789843 chr8:8724257 C/T cg15556689 chr8:8085844 FLJ10661 0.66 6.06 0.48 1.52e-8 Neuroticism; TGCT cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs925228 0.504 rs6755030 chr2:24318343 C/T cg01493198 chr2:24299560 SF3B14 0.73 4.75 0.39 5.43e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg16680214 chr1:154839983 KCNN3 -0.35 -7.28 -0.55 3.32e-11 Prostate cancer; TGCT cis rs7772486 0.558 rs702322 chr6:146007166 G/A cg13319975 chr6:146136371 FBXO30 0.68 6.18 0.49 8.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg06481639 chr22:41940642 POLR3H -0.83 -7.02 -0.53 1.3e-10 Vitiligo; TGCT cis rs9311474 0.508 rs7625743 chr3:52606366 C/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs6933660 0.760 rs3806982 chr6:151774916 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.72 7.39 0.55 1.87e-11 Menarche (age at onset); TGCT cis rs7267979 0.933 rs1130694 chr20:25276297 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8177253 0.901 rs9843728 chr3:133501407 C/T cg11941060 chr3:133502564 NA -0.29 -6.22 -0.49 7.09e-9 Iron status biomarkers; TGCT cis rs13082711 0.595 rs62255583 chr3:27309704 G/T cg02860705 chr3:27208620 NA 0.47 7.19 0.54 5.34e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.88 9.23 0.64 9.1e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs7552167 0.789 rs6424162 chr1:24512576 T/C cg01960748 chr1:24522592 NA -0.49 -5.49 -0.44 2.13e-7 Psoriasis vulgaris; TGCT cis rs7772486 0.840 rs11155451 chr6:146422524 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.56 -0.38 1.23e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2721195 0.967 rs1985022 chr8:145684031 C/T cg15320075 chr8:145703422 NA 0.7 7.13 0.54 7.41e-11 Age at first birth; TGCT cis rs11785400 0.762 rs7007349 chr8:143722673 T/C cg10596483 chr8:143751796 JRK 0.53 5.2 0.42 8e-7 Schizophrenia; TGCT cis rs642803 0.613 rs565427 chr11:65532825 G/A cg27068330 chr11:65405492 SIPA1 0.64 5.69 0.46 8.6e-8 Urate levels; TGCT cis rs6951245 0.638 rs4720486 chr7:1146764 G/A cg09177884 chr7:1199841 ZFAND2A -0.71 -5.64 -0.45 1.1e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs78487399 0.808 rs78098795 chr2:43840361 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.67 4.45 0.37 1.89e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7937682 0.889 rs11213969 chr11:111528441 A/G cg09085632 chr11:111637200 PPP2R1B -1.1 -11.66 -0.72 1.13e-21 Primary sclerosing cholangitis; TGCT cis rs2439831 0.867 rs689616 chr15:43761901 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs2180341 0.538 rs11154402 chr6:127711932 C/A cg27446573 chr6:127587934 RNF146 0.64 6.01 0.47 1.95e-8 Breast cancer; TGCT cis rs4820539 0.641 rs5759602 chr22:23489362 C/T cg14186256 chr22:23484241 RTDR1 -0.83 -9.3 -0.64 6.24e-16 Bone mineral density; TGCT cis rs9796 0.621 rs1659228 chr15:41471978 A/G cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.17 -0.54 5.94e-11 Menopause (age at onset); TGCT cis rs28595532 0.920 rs10001115 chr4:119781867 A/C cg21605333 chr4:119757512 SEC24D 1.44 8.24 0.6 2.03e-13 Cannabis dependence symptom count; TGCT cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -4.82 -0.4 4.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs12210905 1.000 rs12192320 chr6:27090305 G/A cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs4851254 0.660 rs10209201 chr2:100672808 C/T cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs769267 0.965 rs2905425 chr19:19475717 G/C cg03709012 chr19:19516395 GATAD2A -0.76 -6.27 -0.49 5.39e-9 Tonsillectomy; TGCT cis rs7223966 1.000 rs113134232 chr17:61715461 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.83 0.4 3.93e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2486012 1.000 rs1636877 chr1:44387625 G/A cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs2816062 0.735 rs2816054 chr1:18896431 C/T cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs1044826 0.619 rs7375091 chr3:139090389 T/A cg00490450 chr3:139108681 COPB2 -0.53 -4.56 -0.38 1.2e-5 Obesity-related traits; TGCT cis rs853679 0.517 rs9283884 chr6:28135660 C/G cg12963246 chr6:28129442 ZNF389 -0.51 -5.06 -0.41 1.49e-6 Depression; TGCT cis rs6840360 0.693 rs28622593 chr4:152374080 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs2361718 0.500 rs8068856 chr17:78100731 A/G cg02096758 chr17:77394895 HRNBP3 0.24 4.6 0.38 1.01e-5 Yeast infection; TGCT cis rs12142240 0.698 rs61519400 chr1:46855298 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs10992471 0.756 rs7043152 chr9:95138499 A/G cg14631576 chr9:95140430 CENPP -0.3 -4.97 -0.41 2.21e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2730245 0.550 rs2709860 chr7:158651156 A/T cg11984989 chr7:158649758 WDR60 1.02 9.9 0.66 2.22e-17 Height; TGCT cis rs7618915 1.000 rs3852063 chr3:52349204 A/G cg10802521 chr3:52805072 NEK4 -0.55 -5.65 -0.45 1.02e-7 Bipolar disorder; TGCT cis rs17376456 0.825 rs10214278 chr5:93237679 C/T cg25358565 chr5:93447407 FAM172A -1.15 -7.64 -0.57 5.13e-12 Diabetic retinopathy; TGCT cis rs9522267 0.535 rs914037 chr13:112235308 A/G cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg15921436 chr17:44337874 NA 0.56 7.75 0.57 2.88e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg18402987 chr7:1209562 NA 0.39 4.94 0.41 2.48e-6 Longevity;Endometriosis; TGCT cis rs231513 0.911 rs124721 chr17:41959808 T/C cg26893861 chr17:41843967 DUSP3 -0.76 -5.45 -0.44 2.62e-7 Cognitive function; TGCT cis rs4727027 0.901 rs12671341 chr7:148805282 T/C cg23583168 chr7:148888333 NA -0.72 -9.16 -0.64 1.34e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs13217239 0.646 rs10456352 chr6:26990358 A/T cg15659132 chr6:26577336 NA 0.55 5.53 0.44 1.84e-7 Schizophrenia; TGCT cis rs13242816 1.000 rs34325296 chr7:116122409 C/T cg16553024 chr7:116138462 CAV2 -0.44 -4.59 -0.38 1.05e-5 P wave duration; TGCT cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg23758822 chr17:41437982 NA 0.71 6.77 0.52 4.56e-10 Menopause (age at onset); TGCT cis rs3770081 1.000 rs6750765 chr2:86300308 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs28595532 0.920 rs114410095 chr4:119731110 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs1426665 chr4:99027764 C/T cg17366294 chr4:99064904 C4orf37 0.72 7.54 0.56 8.52e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6540559 0.673 rs17015309 chr1:210007218 C/T cg23283495 chr1:209979779 IRF6 0.6 4.5 0.37 1.54e-5 Cleft lip with or without cleft palate; TGCT cis rs12048904 0.619 rs3737581 chr1:101341083 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.82 7.36 0.55 2.2e-11 Multiple sclerosis; TGCT cis rs67478160 0.619 rs12886363 chr14:104273786 T/C cg26031613 chr14:104095156 KLC1 -0.63 -6.42 -0.5 2.64e-9 Schizophrenia; TGCT cis rs10089 1.000 rs10089 chr5:127522543 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.82 7.62 0.56 5.65e-12 Ileal carcinoids; TGCT cis rs1577917 1.000 rs12661204 chr6:86678586 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.3 -0.43 5.05e-7 Response to antipsychotic treatment; TGCT cis rs75686122 0.892 rs75159425 chr8:104629178 A/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs4930561 0.714 rs7130844 chr11:67927517 C/T cg04465784 chr11:67976953 SUV420H1 -0.4 -5.79 -0.46 5.42e-8 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs60843830 1.000 rs6709534 chr2:217334 G/C cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.46 0.5 2.19e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs941408 0.515 rs1736193 chr19:2785273 G/C cg06609049 chr19:2785107 THOP1 1.22 13.43 0.77 6.16e-26 Total cholesterol levels; TGCT cis rs2439831 0.571 rs2470121 chr15:43937618 G/C cg19166733 chr15:44192098 FRMD5 -0.24 -4.89 -0.4 3.08e-6 Lung cancer in ever smokers; TGCT cis rs2067615 0.524 rs10861646 chr12:107071182 C/T cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs137699 0.652 rs137706 chr22:39751400 T/G cg24399712 chr22:39784796 NA -0.81 -6.51 -0.5 1.66e-9 IgG glycosylation; TGCT cis rs4285028 0.731 rs2877561 chr3:121712051 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.74 6.22 0.49 7.08e-9 Multiple sclerosis; TGCT cis rs6570726 0.818 rs398812 chr6:145817271 T/C cg23711669 chr6:146136114 FBXO30 0.71 6.72 0.52 5.91e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs4911259 0.513 rs4287835 chr20:31457337 T/C cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.36e-17 Inflammatory bowel disease; TGCT cis rs10744422 1.000 rs10847869 chr12:123328359 C/G cg25930673 chr12:123319894 HIP1R -0.85 -5.01 -0.41 1.86e-6 Schizophrenia; TGCT cis rs6570726 0.791 rs4896820 chr6:145894957 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9325144 0.723 rs11169518 chr12:39177237 C/A cg26384229 chr12:38710491 ALG10B -0.61 -5.77 -0.46 5.99e-8 Morning vs. evening chronotype; TGCT cis rs2456568 0.548 rs7117597 chr11:93655091 A/G cg16099599 chr11:93583650 C11orf90 -0.39 -4.61 -0.38 9.94e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.6 -5.85 -0.47 4.09e-8 Bipolar disorder; TGCT cis rs9733 0.818 rs11204702 chr1:150663507 C/A cg13175981 chr1:150552382 MCL1 0.43 4.79 0.4 4.61e-6 Tonsillectomy; TGCT cis rs7681440 0.874 rs1372522 chr4:90765280 A/G cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Vitiligo; TGCT cis rs10504229 1.000 rs73591706 chr8:58195633 C/T cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs2742417 0.603 rs2673062 chr3:45763635 A/G cg04837898 chr3:45731254 SACM1L -0.65 -6.95 -0.53 1.84e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6860806 0.661 rs2171247 chr5:131580234 G/T cg24060327 chr5:131705240 SLC22A5 -0.56 -5.58 -0.45 1.47e-7 Breast cancer; TGCT cis rs4889911 0.544 rs1285271 chr17:77834197 C/T cg00646381 chr17:77835854 NA -0.46 -6.53 -0.51 1.49e-9 Electroencephalogram traits; TGCT cis rs7647973 0.769 rs11130181 chr3:49109919 G/A cg05785598 chr3:49045655 WDR6 0.39 4.5 0.37 1.56e-5 Menarche (age at onset); TGCT cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg11644478 chr21:40555479 PSMG1 -0.52 -4.47 -0.37 1.75e-5 Cognitive function; TGCT cis rs11577318 0.853 rs1071849 chr1:26646726 A/G cg04990556 chr1:26633338 UBXN11 -0.59 -4.94 -0.41 2.47e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg01238044 chr22:24384105 GSTT1 -0.54 -5.13 -0.42 1.09e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs992157 0.804 rs7559525 chr2:219150307 A/G cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT cis rs7666738 0.830 rs4699577 chr4:98846513 G/A cg05340658 chr4:99064831 C4orf37 0.52 6.05 0.48 1.61e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1401999 0.966 rs2037379 chr3:183650330 T/C cg01324343 chr3:183735012 ABCC5 0.85 11.41 0.72 4.7e-21 Anterior chamber depth; TGCT cis rs2594989 1.000 rs2606742 chr3:11391717 G/A cg00170343 chr3:11313890 ATG7 0.67 5.04 0.41 1.62e-6 Circulating chemerin levels; TGCT cis rs11096990 0.634 rs3733281 chr4:39271913 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.53 -0.38 1.36e-5 Cognitive function; TGCT cis rs7829975 0.688 rs6995407 chr8:8384647 C/G cg15556689 chr8:8085844 FLJ10661 0.74 6.89 0.53 2.47e-10 Mood instability; TGCT cis rs10540 1.000 rs35898083 chr11:484469 C/T cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs6582630 0.519 rs7305545 chr12:38349223 G/A cg13010199 chr12:38710504 ALG10B 0.58 4.52 0.38 1.41e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs6952808 0.723 rs60995052 chr7:2030007 G/C cg04267008 chr7:1944627 MAD1L1 -0.41 -5.45 -0.44 2.65e-7 Bipolar disorder and schizophrenia; TGCT cis rs9902453 0.791 rs62068629 chr17:28187596 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.62e-11 Coffee consumption (cups per day); TGCT cis rs1008375 1.000 rs10939756 chr4:17693867 C/T cg18681998 chr4:17616180 MED28 0.77 7.35 0.55 2.29e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7726839 0.540 rs11738281 chr5:662547 T/C cg16624210 chr5:671434 TPPP 0.43 4.96 0.41 2.3e-6 Obesity-related traits; TGCT cis rs11673344 0.504 rs1667378 chr19:37492073 C/A cg08039142 chr19:36980659 ZNF566 0.52 4.81 0.4 4.23e-6 Obesity-related traits; TGCT cis rs7752195 0.730 rs79249301 chr6:25260918 T/C cg16898833 chr6:26189333 HIST1H4D 1.18 5.52 0.44 1.89e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6840360 0.571 rs11723395 chr4:152524191 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs16867321 0.671 rs890059 chr2:181510905 G/C cg23363182 chr2:181467187 NA -0.45 -4.64 -0.38 8.67e-6 Obesity; TGCT cis rs11792861 0.781 rs28361106 chr9:111762385 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.51 4.73 0.39 5.99e-6 Menarche (age at onset); TGCT cis rs796364 1.000 rs10178177 chr2:200829993 G/A cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs8072100 0.967 rs4338849 chr17:45512483 A/G cg08085267 chr17:45401833 C17orf57 -0.51 -5.6 -0.45 1.29e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs433598 0.704 rs151310 chr16:20663135 T/G cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -4.94 -0.41 2.47e-6 Schizophrenia; TGCT cis rs77948430 0.655 rs78007284 chr8:13157827 A/C cg25598624 chr8:12235727 FAM66A 0.31 4.59 0.38 1.08e-5 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs35934224 0.891 rs5993850 chr22:19869703 C/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.34 -0.43 4.3e-7 Glaucoma (primary open-angle); TGCT cis rs9902453 0.967 rs1906451 chr17:28515479 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.68 6.4 0.5 2.85e-9 Coffee consumption (cups per day); TGCT cis rs3008870 0.755 rs2815380 chr1:67510857 A/G cg08660285 chr1:67390436 MIER1;WDR78 -0.78 -7.18 -0.54 5.61e-11 Lymphocyte percentage of white cells; TGCT cis rs6862531 0.959 rs72652809 chr5:143092525 T/G cg06916709 chr5:142092905 NA -0.64 -4.45 -0.37 1.86e-5 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Delta-6 desaturase activity; TGCT cis rs7584330 0.695 rs6709497 chr2:238368925 C/T cg14458575 chr2:238380390 NA 0.49 7.88 0.58 1.41e-12 Prostate cancer; TGCT cis rs7296418 0.754 rs1619283 chr12:123717362 A/G cg00376283 chr12:123451042 ABCB9 0.8 7.23 0.54 4.43e-11 Platelet count; TGCT cis rs79349575 0.783 rs12601858 chr17:47017477 T/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs9911578 1.000 rs304299 chr17:56838472 C/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT trans rs7618501 0.633 rs13060128 chr3:50025028 A/G cg21659725 chr3:3221576 CRBN 0.76 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis); TGCT cis rs7211079 0.582 rs72852528 chr17:78136089 T/C cg09238746 chr17:78121135 EIF4A3 -0.74 -5.18 -0.42 8.9e-7 Myocardial infarction; TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg26338869 chr17:61819248 STRADA -0.5 -4.58 -0.38 1.12e-5 Prudent dietary pattern; TGCT cis rs11690462 0.963 rs6731447 chr2:26590118 C/T cg04726446 chr2:26624865 C2orf39 0.44 4.73 0.39 5.97e-6 Coronary artery disease; TGCT cis rs17270561 0.887 rs12201170 chr6:25866247 A/G cg17691542 chr6:26056736 HIST1H1C 0.82 4.91 0.4 2.76e-6 Iron status biomarkers; TGCT cis rs7267979 0.903 rs6050481 chr20:25224580 C/T cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4555082 0.645 rs2816605 chr14:105715515 C/T cg01266790 chr14:105781312 PACS2 0.55 4.51 0.38 1.49e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs514406 0.547 rs377808 chr1:53190359 T/G cg25767906 chr1:53392781 SCP2 -0.44 -4.78 -0.39 4.84e-6 Monocyte count; TGCT cis rs889312 0.500 rs832580 chr5:56172646 T/C cg24531977 chr5:56204891 C5orf35 -0.5 -5.09 -0.42 1.28e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs926938 0.527 rs360584 chr1:115463181 G/A cg12756093 chr1:115239321 AMPD1 0.34 4.95 0.41 2.35e-6 Autism; TGCT cis rs1580019 0.587 rs2392069 chr7:32547154 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.15 0.79 1.17e-27 Cognitive ability; TGCT cis rs7647973 0.769 rs4974081 chr3:49070499 A/G cg07636037 chr3:49044803 WDR6 -0.81 -6.68 -0.51 7.37e-10 Menarche (age at onset); TGCT cis rs11785400 1.000 rs13265663 chr8:143732255 A/C cg10596483 chr8:143751796 JRK 0.54 5.77 0.46 5.95e-8 Schizophrenia; TGCT cis rs11190604 0.943 rs11190581 chr10:102243387 T/G cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10089 1.000 rs4836369 chr5:127486462 A/G cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.27e-5 Ileal carcinoids; TGCT cis rs7172809 0.599 rs59386622 chr15:77752693 G/A cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs9972944 0.756 rs2318868 chr17:63767592 G/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs11112613 0.713 rs11112592 chr12:105951702 C/T cg03607813 chr12:105948248 NA -0.47 -5.8 -0.46 5.28e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7714584 1.000 rs13361189 chr5:150223387 A/G cg22134413 chr5:150180641 NA 0.94 7.09 0.54 9.11e-11 Crohn's disease; TGCT cis rs4383453 0.559 rs903574 chr3:123099807 C/G cg04890266 chr3:123102914 ADCY5 -0.5 -8.34 -0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs35306767 0.761 rs11253538 chr10:1011166 C/T cg20503657 chr10:835505 NA 0.57 6.33 0.49 4.06e-9 Eosinophil percentage of granulocytes; TGCT cis rs11209002 0.524 rs982131 chr1:67542360 T/C cg02640540 chr1:67518911 SLC35D1 0.53 4.45 0.37 1.86e-5 Crohn's disease; TGCT cis rs10992471 0.528 rs3780347 chr9:95266812 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.51 -4.78 -0.39 4.9e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3213961 0.529 rs6708 chr2:33789534 A/G cg04131969 chr2:33951647 MYADML 0.68 5.39 0.44 3.46e-7 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs2204008 0.659 rs4002655 chr12:38169881 T/G cg13010199 chr12:38710504 ALG10B 0.62 4.89 0.4 3.09e-6 Bladder cancer; TGCT cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.04 8.75 0.62 1.26e-14 Platelet count; TGCT cis rs933688 1.000 rs10059163 chr5:90742444 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.43 0.6 7.52e-14 Smoking behavior; TGCT cis rs12477438 0.798 rs6740267 chr2:99561867 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.7 -6.14 -0.48 1.05e-8 Chronic sinus infection; TGCT cis rs1008375 0.872 rs2315552 chr4:17627294 A/G cg16339924 chr4:17578868 LAP3 0.56 4.66 0.39 7.87e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7618915 0.851 rs34228726 chr3:52322797 A/G cg10802521 chr3:52805072 NEK4 -0.55 -5.69 -0.45 8.83e-8 Bipolar disorder; TGCT cis rs3806843 0.576 rs251376 chr5:140253689 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.41 4.92 0.4 2.68e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7927592 0.763 rs1193699 chr11:68249480 C/G cg16797656 chr11:68205561 LRP5 0.26 4.48 0.37 1.67e-5 Total body bone mineral density; TGCT trans rs6089829 0.962 rs3746749 chr20:61667333 T/C cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467711 0.932 rs11966360 chr6:26316982 A/G cg26531700 chr6:26746687 NA -0.95 -5.43 -0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.830 rs34244876 chr4:99031336 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.690 rs647661 chr11:68625875 T/C cg06112835 chr11:68658793 MRPL21 0.49 8.21 0.59 2.41e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg13695892 chr22:41940480 POLR3H 0.78 7.62 0.56 5.73e-12 Vitiligo; TGCT cis rs9393777 0.513 rs13219181 chr6:27136225 A/G cg16898833 chr6:26189333 HIST1H4D 0.74 4.48 0.37 1.71e-5 Intelligence (multi-trait analysis); TGCT cis rs35797862 1 rs35797862 chr1:93738515 A/AAG cg17826107 chr1:92977322 EVI5 0.23 5.12 0.42 1.15e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes;Eosinophil counts; TGCT cis rs6952808 0.594 rs3778969 chr7:2139990 A/G cg22963979 chr7:1858916 MAD1L1 0.39 6.34 0.49 3.83e-9 Bipolar disorder and schizophrenia; TGCT cis rs372883 0.648 rs1153292 chr21:30689195 G/T cg24692254 chr21:30365293 RNF160 -0.53 -4.78 -0.39 4.97e-6 Pancreatic cancer; TGCT cis rs8038465 0.789 rs57909886 chr15:73973662 T/C cg15420318 chr15:73925796 NPTN 0.74 7.57 0.56 7.25e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs514406 0.825 rs6693210 chr1:53223398 A/G cg08859206 chr1:53392774 SCP2 0.4 6.01 0.48 1.91e-8 Monocyte count; TGCT cis rs76419734 0.850 rs58775257 chr4:106809983 G/A cg24545054 chr4:106630052 GSTCD;INTS12 1.0 4.66 0.39 7.95e-6 Post bronchodilator FEV1; TGCT cis rs2806561 0.765 rs682766 chr1:23516397 C/G cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs2948294 0.566 rs13261997 chr8:8112295 C/T cg15556689 chr8:8085844 FLJ10661 0.78 6.41 0.5 2.74e-9 Red cell distribution width; TGCT cis rs1153858 1.000 rs56669689 chr15:45637729 A/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs9916302 0.706 rs4795375 chr17:37662932 T/C cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs1862618 0.671 rs2034244 chr5:56242774 T/C cg20203395 chr5:56204925 C5orf35 0.52 4.89 0.4 3.01e-6 Initial pursuit acceleration; TGCT cis rs7226408 0.857 rs72887036 chr18:34475737 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7715806 0.500 rs888788 chr5:74988336 C/T cg19683494 chr5:74908142 NA 0.57 4.93 0.4 2.57e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs9611565 0.592 rs5758405 chr22:42076381 C/A cg17554472 chr22:41940697 POLR3H 0.5 5.36 0.43 3.92e-7 Vitiligo; TGCT cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg08859206 chr1:53392774 SCP2 0.33 4.61 0.38 9.7e-6 Monocyte count; TGCT cis rs6545883 0.931 rs778768 chr2:61790289 C/G cg15711740 chr2:61764176 XPO1 -0.56 -5.08 -0.41 1.37e-6 Tuberculosis; TGCT cis rs8180040 0.726 rs61729713 chr3:47027192 A/G cg27129171 chr3:47204927 SETD2 -0.7 -8.8 -0.62 9.59e-15 Colorectal cancer; TGCT cis rs7949030 0.626 rs7943191 chr11:62328551 A/G cg11742103 chr11:62369870 EML3;MTA2 0.61 8.71 0.62 1.65e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6665290 0.904 rs6684821 chr1:227190233 G/A cg10327440 chr1:227177885 CDC42BPA -1.0 -20.5 -0.88 1.18e-41 Myeloid white cell count; TGCT cis rs7552404 0.924 rs1146574 chr1:76202671 A/G cg03433033 chr1:76189801 ACADM 0.77 9.25 0.64 8.26e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4851266 0.865 rs11695996 chr2:100854336 C/T cg22139774 chr2:100720529 AFF3 -0.32 -4.66 -0.39 7.89e-6 Educational attainment; TGCT cis rs669446 0.562 rs4660259 chr1:44194534 A/G cg12908607 chr1:44402522 ARTN -0.62 -7.25 -0.55 3.99e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs2180341 0.920 rs1073932 chr6:127682009 G/T cg27446573 chr6:127587934 RNF146 1.14 10.91 0.7 7.51e-20 Breast cancer; TGCT cis rs8177179 1.000 rs8177179 chr3:133463457 G/A cg16262614 chr3:133464971 TF 0.34 4.57 0.38 1.15e-5 Iron status biomarkers (transferrin levels); TGCT cis rs12188164 0.686 rs72711369 chr5:420517 C/T cg26850624 chr5:429559 AHRR -0.21 -4.98 -0.41 2.06e-6 Cystic fibrosis severity; TGCT cis rs172166 0.516 rs1225710 chr6:28100640 C/T cg13525197 chr6:28411240 ZSCAN23 0.48 4.65 0.39 8.38e-6 Cardiac Troponin-T levels; TGCT cis rs13424612 1.000 rs4149556 chr2:240915307 C/T cg26363272 chr2:240904871 NDUFA10 0.28 4.79 0.4 4.65e-6 Odorant perception (isobutyraldehyde); TGCT cis rs17152411 1.000 rs7083336 chr10:126590771 T/C cg07906193 chr10:126599966 NA 0.42 5.16 0.42 9.55e-7 Height; TGCT cis rs11122272 0.735 rs2246645 chr1:231497393 T/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.68 -0.51 7.25e-10 Hemoglobin concentration; TGCT cis rs2456568 0.867 rs1395384 chr11:93663250 C/T cg17595323 chr11:93583763 C11orf90 0.46 5.93 0.47 2.85e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2721811 0.535 rs2721805 chr7:24780316 C/T cg17569154 chr7:24781545 DFNA5 0.22 4.68 0.39 7.29e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs11098499 0.954 rs10031665 chr4:120422852 T/C cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs9399135 0.967 rs2150681 chr6:135375232 A/G cg24558204 chr6:135376177 HBS1L -0.46 -4.58 -0.38 1.11e-5 Red blood cell count; TGCT cis rs2073300 1.000 rs6114141 chr20:23460620 T/G cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs6918586 0.532 rs198800 chr6:26139933 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.65 -6.2 -0.49 7.65e-9 Schizophrenia; TGCT cis rs12681288 0.676 rs62488537 chr8:1011962 A/C cg04851639 chr8:1020857 NA -0.31 -5.17 -0.42 8.94e-7 Schizophrenia; TGCT cis rs10769945 0.730 rs217208 chr11:1974892 C/G cg02850416 chr11:1986266 NA -0.26 -4.44 -0.37 1.99e-5 DNA methylation (variation); TGCT cis rs1008375 0.932 rs7697329 chr4:17657853 C/A cg10189774 chr4:17578691 LAP3 0.53 4.6 0.38 1.04e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9291683 0.538 rs11727199 chr4:10036190 C/T cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.26e-14 Bone mineral density; TGCT cis rs12497850 0.897 rs9884022 chr3:48956862 G/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.48 -0.44 2.23e-7 Parkinson's disease; TGCT cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7809950 1.000 rs2237672 chr7:107131563 A/C cg23024343 chr7:107201750 COG5 -0.34 -5.43 -0.44 2.92e-7 Coronary artery disease; TGCT cis rs6490294 0.748 rs7295665 chr12:112379271 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs2836633 0.859 rs8132069 chr21:40032611 T/C cg05519781 chr21:40033154 ERG 0.68 6.54 0.51 1.47e-9 Coronary artery disease; TGCT cis rs1395 0.744 rs7600932 chr2:27474869 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs7119038 0.607 rs12365699 chr11:118743286 C/T cg19308663 chr11:118741387 NA 0.27 4.76 0.39 5.22e-6 Sjögren's syndrome; TGCT cis rs6754311 0.638 rs1011361 chr2:136553639 G/A cg07169764 chr2:136633963 MCM6 -0.66 -6.04 -0.48 1.63e-8 Mosquito bite size; TGCT cis rs1971762 0.527 rs7972401 chr12:53940046 T/C cg16917193 chr12:54089295 NA 1.02 10.38 0.68 1.5e-18 Height; TGCT cis rs12681288 0.676 rs6983981 chr8:1016011 A/C cg04851639 chr8:1020857 NA -0.36 -6.79 -0.52 4.13e-10 Schizophrenia; TGCT trans rs7726839 0.540 rs4957080 chr5:644552 A/C cg25482853 chr8:67687455 SGK3 -1.19 -10.3 -0.68 2.4e-18 Obesity-related traits; TGCT cis rs2147959 0.766 rs6703575 chr1:228743667 G/C cg22700015 chr1:228743131 NA -0.59 -4.78 -0.39 4.94e-6 Adult asthma; TGCT cis rs3008870 0.755 rs1535365 chr1:67497613 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.25 0.6 1.95e-13 Lymphocyte percentage of white cells; TGCT cis rs2243480 1.000 rs313809 chr7:65499983 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs1403694 0.695 rs1851665 chr3:186436398 A/G cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs3820068 0.581 rs2861387 chr1:15951296 G/A cg05660106 chr1:15850417 CASP9 0.86 8.48 0.61 5.53e-14 Systolic blood pressure; TGCT cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs9788721 0.836 rs17484235 chr15:78761414 C/G cg18825076 chr15:78729989 IREB2 -0.34 -5.1 -0.42 1.21e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs13191362 1.000 rs35575481 chr6:163007746 T/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs977747 1.000 rs977747 chr1:47684677 T/G cg03885399 chr1:47691550 TAL1 -0.39 -4.71 -0.39 6.41e-6 Body mass index; TGCT cis rs9611565 0.649 rs6002480 chr22:42176917 A/T cg13695892 chr22:41940480 POLR3H -0.79 -7.49 -0.56 1.15e-11 Vitiligo; TGCT trans rs57221529 0.766 rs28563961 chr5:554498 C/G cg25482853 chr8:67687455 SGK3 1.2 9.97 0.67 1.49e-17 Lung disease severity in cystic fibrosis; TGCT cis rs72627509 0.638 rs7658601 chr4:57781347 C/T cg26694713 chr4:57773883 REST 0.75 6.77 0.52 4.59e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4523957 0.614 rs2316512 chr17:2064710 A/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9911578 0.967 rs4598970 chr17:57076893 T/A cg12560992 chr17:57184187 TRIM37 -0.78 -9.58 -0.65 1.35e-16 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.520 rs13035311 chr2:99717322 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs3947 1.000 rs1692812 chr8:11703523 T/G cg02840367 chr8:11660030 FDFT1 0.91 6.66 0.51 7.98e-10 Blood protein levels; TGCT cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs2933343 0.700 rs2630257 chr3:128644015 T/C cg11901034 chr3:128598214 ACAD9 -0.65 -6.05 -0.48 1.55e-8 IgG glycosylation; TGCT cis rs950776 0.518 rs12906846 chr15:78825295 G/A cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs10751667 0.666 rs6597960 chr11:977036 C/T cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs12497850 0.931 rs9682444 chr3:48852639 A/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs9650657 0.655 rs4841434 chr8:10586123 T/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.45 -0.37 1.85e-5 Neuroticism; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 -0.44 -4.98 -0.41 2.05e-6 Lymphocyte counts; TGCT cis rs13191362 1.000 rs34773528 chr6:163088796 G/C cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.49 0.65 2.19e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs922182 0.721 rs7180239 chr15:64309643 G/A cg02919090 chr15:64263738 DAPK2 0.25 4.54 0.38 1.3e-5 Blood protein levels; TGCT cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg03264133 chr6:25882463 NA -0.53 -5.53 -0.44 1.8e-7 Blood metabolite levels; TGCT cis rs13256369 1.000 rs13271966 chr8:8575472 T/C cg18904891 chr8:8559673 CLDN23 0.64 5.89 0.47 3.36e-8 Obesity-related traits; TGCT cis rs950776 0.518 rs12903129 chr15:78819606 C/T cg06917634 chr15:78832804 PSMA4 0.96 9.43 0.65 2.99e-16 Sudden cardiac arrest; TGCT cis rs13088645 0.541 rs9842113 chr3:134192338 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.68 -6.78 -0.52 4.37e-10 Coronary artery disease; TGCT cis rs1862618 0.853 rs832584 chr5:56179212 A/G cg03609598 chr5:56110824 MAP3K1 0.61 4.93 0.4 2.62e-6 Initial pursuit acceleration; TGCT cis rs2832191 0.791 rs2832179 chr21:30480366 C/T cg24692254 chr21:30365293 RNF160 -0.95 -10.52 -0.69 7.06e-19 Dental caries; TGCT cis rs138249 1.000 rs138250 chr22:50570361 A/G cg24864161 chr22:50528282 MOV10L1 0.47 4.78 0.39 4.9100000000000004e-06 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs7681440 0.904 rs1372521 chr4:90765223 G/A cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs10174077 0.687 rs4664491 chr2:152479986 C/T cg19508488 chr2:152266495 RIF1 0.62 5.83 0.46 4.59e-8 Squamous cell lung carcinoma; TGCT cis rs651907 0.535 rs61396602 chr3:101509046 T/C cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs6547741 0.935 rs2384626 chr2:27773648 A/G cg27432699 chr2:27873401 GPN1 0.19 4.7 0.39 6.92e-6 Oral cavity cancer; TGCT cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg10117171 chr1:25599238 RHD -0.34 -5.5 -0.44 2.05e-7 Erythrocyte sedimentation rate; TGCT cis rs7647973 0.731 rs7617480 chr3:49210732 G/T cg07690219 chr3:49449608 TCTA;RHOA 0.63 4.83 0.4 3.87e-6 Menarche (age at onset); TGCT cis rs3806843 0.712 rs2530244 chr5:140109155 A/G cg19875535 chr5:140030758 IK -0.35 -5.94 -0.47 2.63e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs78487399 0.808 rs72865267 chr2:43726328 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.82 -0.4 4.03e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1552244 0.816 rs56387520 chr3:10042782 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs3806843 0.576 rs265316 chr5:140290843 T/C cg09824255 chr5:140014002 CD14 0.25 4.48 0.37 1.69e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs698813 0.674 rs3738985 chr2:44502788 A/C cg00619915 chr2:44497795 NA -0.22 -4.95 -0.41 2.35e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs7208859 0.614 rs9914534 chr17:29202664 G/A cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17401966 0.838 rs61775885 chr1:10281445 T/C cg19773385 chr1:10388646 KIF1B -0.22 -4.65 -0.39 8.41e-6 Hepatocellular carcinoma; TGCT cis rs1799949 1.000 rs33918839 chr17:41329172 T/C cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs6912958 0.781 rs6916732 chr6:88259225 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs514406 0.505 rs427319 chr1:53178807 T/G cg08859206 chr1:53392774 SCP2 -0.36 -5.23 -0.42 7.05e-7 Monocyte count; TGCT cis rs7226408 0.857 rs56331183 chr18:34621913 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9902453 0.874 rs4474741 chr17:28148117 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.81 -0.52 3.74e-10 Coffee consumption (cups per day); TGCT cis rs1150668 0.796 rs1005125 chr6:28367355 G/A cg13525197 chr6:28411240 ZSCAN23 -0.5 -4.87 -0.4 3.3e-6 Pubertal anthropometrics; TGCT cis rs7804356 0.651 rs1030648 chr7:26802672 T/C cg03456212 chr7:26904342 SKAP2 -0.54 -4.56 -0.38 1.22e-5 Type 1 diabetes; TGCT cis rs514406 0.505 rs269287 chr1:53168842 T/C cg01802117 chr1:53393560 SCP2 -0.42 -4.85 -0.4 3.64e-6 Monocyte count; TGCT cis rs9818758 0.607 rs11706052 chr3:49064110 A/G cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1670533 1.000 rs2290411 chr4:1051077 T/C cg27284194 chr4:1044797 NA 0.68 5.87 0.47 3.76e-8 Recombination rate (females); TGCT cis rs10779751 1.000 rs6679878 chr1:11306882 A/G cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs10927875 0.864 rs6674071 chr1:16144855 G/C cg21385522 chr1:16154831 NA -0.89 -11.06 -0.7 3.27e-20 Dilated cardiomyopathy; TGCT cis rs854765 0.583 rs28428991 chr17:17827649 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs868036 0.718 rs4776984 chr15:68118194 A/C cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs2795502 0.938 rs3121324 chr10:43379515 C/T cg20628663 chr10:43360327 NA 0.43 6.2 0.49 7.57e-9 Blood protein levels; TGCT cis rs28595532 0.841 rs56046449 chr4:119769302 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs2120019 0.935 rs8043181 chr15:75380424 T/C cg09165964 chr15:75287851 SCAMP5 -1.06 -8.28 -0.6 1.63e-13 Blood trace element (Zn levels); TGCT cis rs6570726 0.791 rs9373464 chr6:145907167 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs72634258 0.519 rs36040967 chr1:7931804 A/G cg26816564 chr1:7831052 VAMP3 0.65 4.98 0.41 2.11e-6 Inflammatory bowel disease; TGCT cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg23221052 chr5:179740743 GFPT2 -0.33 -5.09 -0.42 1.27e-6 Height; TGCT cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg03264133 chr6:25882463 NA 0.49 5.14 0.42 1.05e-6 Blood metabolite levels; TGCT cis rs7659604 0.582 rs3217780 chr4:122737278 T/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.26 -0.43 6.07e-7 Type 2 diabetes; TGCT cis rs3806843 0.518 rs173471 chr5:140335226 A/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs1878931 0.726 rs3843728 chr16:3448251 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.99 12.29 0.74 3.41e-23 Body mass index (adult); TGCT cis rs3733585 0.605 rs56178126 chr4:10123581 C/T cg11266682 chr4:10021025 SLC2A9 -0.56 -6.36 -0.5 3.55e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg08219700 chr8:58056026 NA 0.41 4.98 0.41 2.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089584 0.927 rs11697597 chr20:60584748 C/T cg13770153 chr20:60521292 NA -0.54 -7.35 -0.55 2.31e-11 Body mass index; TGCT cis rs9302065 1.000 rs9302065 chr13:95971016 C/T cg26751094 chr13:95954534 ABCC4 0.31 5.19 0.42 8.16e-7 Blood metabolite levels; TGCT cis rs28595532 1.000 rs73842212 chr4:119638122 A/G cg21605333 chr4:119757512 SEC24D 1.36 7.4 0.55 1.82e-11 Cannabis dependence symptom count; TGCT cis rs11532322 1 rs11532322 chr12:123731423 A/G cg00376283 chr12:123451042 ABCB9 0.79 6.72 0.52 6e-10 Schizophrenia; TGCT cis rs8031584 0.678 rs8035703 chr15:31168472 T/C cg14829155 chr15:31115871 NA -0.36 -4.72 -0.39 6.14e-6 Huntington's disease progression; TGCT cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg15659132 chr6:26577336 NA -0.55 -5.37 -0.43 3.7e-7 Schizophrenia; TGCT cis rs7926906 1.000 rs1404532 chr11:90538258 A/T cg26138821 chr11:89956704 CHORDC1 0.48 5.15 0.42 9.96e-7 Intelligence (multi-trait analysis); TGCT cis rs2594989 0.887 rs2443717 chr3:11521493 T/C cg00170343 chr3:11313890 ATG7 0.7 5.22 0.42 7.17e-7 Circulating chemerin levels; TGCT cis rs9467773 1.000 rs9467797 chr6:26568473 A/T cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs7843479 0.965 rs17581910 chr8:21799626 A/G cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs7674212 0.581 rs10516496 chr4:103942165 C/T cg16532752 chr4:104119610 CENPE -0.58 -5.21 -0.42 7.7300000000000005e-07 Type 2 diabetes; TGCT cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.64 -0.57 5.17e-12 Initial pursuit acceleration; TGCT cis rs9611565 0.879 rs2235845 chr22:41729294 T/G cg13695892 chr22:41940480 POLR3H -0.72 -7.33 -0.55 2.61e-11 Vitiligo; TGCT cis rs875971 1.000 rs6945843 chr7:65734783 G/A cg18876405 chr7:65276391 NA -0.34 -5.08 -0.41 1.38e-6 Aortic root size; TGCT cis rs11030122 0.632 rs4910596 chr11:4084604 A/G cg18678763 chr11:4115507 RRM1 -0.48 -5.88 -0.47 3.49e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs7769051 1.000 rs9493454 chr6:133144629 G/T cg07930552 chr6:133119739 C6orf192 -0.96 -5.08 -0.41 1.37e-6 Type 2 diabetes nephropathy; TGCT cis rs3733585 0.578 rs6837224 chr4:9955255 G/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9372498 0.505 rs62424173 chr6:118780507 C/G cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs9790314 0.586 rs67077657 chr3:161138521 A/G cg03342759 chr3:160939853 NMD3 -0.53 -5.32 -0.43 4.74e-7 Morning vs. evening chronotype; TGCT cis rs56176327 0.600 rs7628207 chr3:49754970 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Intelligence (multi-trait analysis); TGCT cis rs2455799 0.613 rs10510443 chr3:15829127 A/G cg16303742 chr3:15540471 COLQ -0.24 -4.51 -0.38 1.47e-5 Mean platelet volume; TGCT cis rs1990950 0.692 rs10070466 chr5:156839607 G/A cg25387487 chr5:157003181 ADAM19 0.29 4.54 0.38 1.29e-5 Lung function (FEV1/FVC); TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg26354017 chr1:205819088 PM20D1 -0.54 -6.83 -0.52 3.45e-10 Monocyte percentage of white cells; TGCT cis rs9914988 0.887 rs28873200 chr17:27149512 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs2046867 0.862 rs62251657 chr3:72832076 C/T cg25664220 chr3:72788482 NA -0.58 -7.21 -0.54 4.9e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.830 rs9994346 chr4:99037986 A/G cg05340658 chr4:99064831 C4orf37 0.48 4.99 0.41 2.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2730260 0.537 rs56260213 chr7:158875921 C/T cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs6724607 0.905 rs10173771 chr2:191439248 T/C cg21644426 chr2:191273491 MFSD6 0.59 5.81 0.46 4.92e-8 Pulse pressure; TGCT cis rs57920188 0.585 rs12124643 chr1:4071209 C/T cg20703997 chr1:4087676 NA 0.45 5.49 0.44 2.13e-7 Interleukin-17 levels; TGCT cis rs4654899 0.897 rs710311 chr1:21062001 T/C cg01072550 chr1:21505969 NA -0.48 -7.56 -0.56 7.78e-12 Superior frontal gyrus grey matter volume; TGCT cis rs9303401 0.614 rs62084384 chr17:57126842 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.82 0.46 4.8e-8 Cognitive test performance; TGCT cis rs4568518 0.530 rs10273476 chr7:17998418 G/A cg03009463 chr7:17980271 SNX13 0.57 4.51 0.38 1.47e-5 Measles; TGCT cis rs12142240 0.698 rs72677592 chr1:46818288 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT trans rs877282 1.000 rs877281 chr10:771557 T/G cg22713356 chr15:30763199 NA 1.2 10.36 0.68 1.66e-18 Uric acid levels; TGCT cis rs10504229 0.906 rs61638902 chr8:58193511 A/C cg21724239 chr8:58056113 NA 0.35 4.76 0.39 5.26e-6 Developmental language disorder (linguistic errors); TGCT cis rs6918586 0.658 rs198819 chr6:26124430 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.68 -6.46 -0.5 2.15e-9 Schizophrenia; TGCT cis rs3733585 0.699 rs28613263 chr4:9964880 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.66e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3015497 0.789 rs11621971 chr14:51124527 C/T cg04730355 chr14:51134070 SAV1 0.62 6.06 0.48 1.48e-8 Mean platelet volume; TGCT cis rs7666738 0.830 rs36028444 chr4:98968635 G/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs911555 0.713 rs11848796 chr14:103978686 T/C cg12935359 chr14:103987150 CKB -0.33 -4.66 -0.39 7.91e-6 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.673 rs73277978 chr17:29191449 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2273156 1.000 rs8017191 chr14:35469991 G/A cg15394648 chr14:35761551 PSMA6 -0.6 -4.48 -0.37 1.69e-5 Immunoglobulin light chain (AL) amyloidosis; TGCT trans rs7824557 0.527 rs2736296 chr8:11234844 G/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.42e-10 Retinal vascular caliber; TGCT cis rs9910055 0.762 rs227579 chr17:42223134 A/T cg19774624 chr17:42201019 HDAC5 0.85 8.95 0.63 4.27e-15 Total body bone mineral density; TGCT cis rs2692947 0.616 rs2301707 chr2:96931846 T/C cg23100626 chr2:96804247 ASTL 0.5 6.62 0.51 9.75e-10 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg13395646 chr4:1353034 KIAA1530 0.4 4.98 0.41 2.1e-6 Obesity-related traits; TGCT cis rs7542091 1.000 rs7542091 chr1:210031948 G/C cg23283495 chr1:209979779 IRF6 0.49 4.97 0.41 2.16e-6 Monobrow; TGCT cis rs6426558 0.559 rs2813947 chr1:227459413 G/T cg10327440 chr1:227177885 CDC42BPA 0.58 6.76 0.52 4.75e-10 Neutrophil percentage of white cells; TGCT cis rs892961 0.932 rs35657663 chr17:75412482 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs909674 0.690 rs5750825 chr22:39831278 A/G cg01416388 chr22:39784598 NA -0.74 -6.78 -0.52 4.37e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs875971 1.000 rs6958271 chr7:65979331 A/C cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs1215050 0.791 rs9993992 chr4:98810851 C/G cg17366294 chr4:99064904 C4orf37 0.54 5.79 0.46 5.38e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs908922 0.676 rs7550769 chr1:152531213 G/A cg20991723 chr1:152506922 NA 0.45 6.05 0.48 1.6e-8 Hair morphology; TGCT cis rs35306767 0.855 rs11253465 chr10:897208 A/C cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs6681544 0.760 rs4970640 chr1:82429237 A/G cg04226724 chr1:82268649 LPHN2 -0.48 -4.95 -0.41 2.42e-6 Metabolite levels (X-11787); TGCT cis rs9650657 0.501 rs3021500 chr8:11023997 G/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.54 -0.38 1.3e-5 Neuroticism; TGCT cis rs2204008 0.687 rs2320523 chr12:38251397 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.33 0.55 2.58e-11 Bladder cancer; TGCT cis rs3617 0.625 rs6769789 chr3:52874446 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs7613875 0.620 rs3774734 chr3:50108792 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.8 -8.32 -0.6 1.31e-13 Body mass index; TGCT cis rs1865760 0.827 rs9295681 chr6:25944117 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.39 0.5 3.02e-9 Height; TGCT cis rs7017914 0.967 rs7012404 chr8:71668698 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs1008375 0.966 rs6449329 chr4:17703677 T/C cg18681998 chr4:17616180 MED28 0.78 7.37 0.55 2.06e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9902453 0.904 rs7208579 chr17:28263067 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.26 0.6 1.9e-13 Coffee consumption (cups per day); TGCT cis rs6089829 0.855 rs6090203 chr20:61663632 G/A cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs6988636 1.000 rs7002021 chr8:124185250 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs7666738 0.753 rs28463863 chr4:98844444 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.36 0.43 3.96e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4689388 0.889 rs4629534 chr4:6294124 G/T cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9325144 0.505 rs10785560 chr12:38636622 C/T cg13010199 chr12:38710504 ALG10B 0.61 5.42 0.44 2.93e-7 Morning vs. evening chronotype; TGCT cis rs2439831 0.867 rs8041132 chr15:43635136 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs9948 0.786 rs72809850 chr2:97449762 A/C cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs7918232 0.941 rs7907988 chr10:27444344 T/G cg14442939 chr10:27389572 ANKRD26 0.8 5.32 0.43 4.7e-7 Breast cancer; TGCT cis rs2243480 1.000 rs11538349 chr7:65421871 C/T cg07424592 chr7:64974309 NA 1.32 8.25 0.6 1.92e-13 Diabetic kidney disease; TGCT cis rs9527 0.615 rs36045108 chr10:104697929 G/A cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs7666738 0.830 rs2015828 chr4:98984594 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs546131 0.928 rs550313 chr11:34830919 C/T cg06937548 chr11:34938143 PDHX;APIP 0.68 6.17 0.48 8.82e-9 Lung disease severity in cystic fibrosis; TGCT cis rs4851266 1.000 rs11686280 chr2:100827718 C/A cg07810366 chr2:100720526 AFF3 -0.39 -5.55 -0.45 1.65e-7 Educational attainment; TGCT cis rs5751150 1 rs5751150 chr22:42153292 T/G cg13695892 chr22:41940480 POLR3H 0.87 8.24 0.59 2.06e-13 Cannabis dependence symptom count; TGCT cis rs478304 0.754 rs2004649 chr11:65380916 G/A cg17480646 chr11:65405466 SIPA1 -0.55 -7.09 -0.54 9.2e-11 Acne (severe); TGCT cis rs8031584 0.918 rs35396566 chr15:31263057 T/C cg08704250 chr15:31115839 NA -0.35 -4.53 -0.38 1.38e-5 Huntington's disease progression; TGCT trans rs17685 0.712 rs11770149 chr7:75791644 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 9.1 0.63 1.93e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2735413 0.564 rs7201557 chr16:78110059 C/A cg09132178 chr16:78079569 NA 0.37 4.8 0.4 4.4e-6 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs7312933 0.558 rs1051453 chr12:42852217 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 4.99 0.41 2.02e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7949030 0.765 rs11553576 chr11:62378801 T/C cg13298116 chr11:62369859 EML3;MTA2 0.65 9.75 0.66 5.01e-17 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3617 0.522 rs6773650 chr3:52897095 A/T cg11645453 chr3:52864694 ITIH4 0.26 4.89 0.4 3e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs950169 0.919 rs17300292 chr15:84762568 G/C cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.07e-8 Schizophrenia; TGCT cis rs875971 0.862 rs6945775 chr7:65968974 G/A cg11764359 chr7:65958608 NA 0.58 5.34 0.43 4.22e-7 Aortic root size; TGCT cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs7914558 0.966 rs10883805 chr10:104708251 T/C cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2180341 0.814 rs6905553 chr6:127727407 A/G cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs7264396 0.790 rs2425097 chr20:34308926 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.96e-7 Total cholesterol levels; TGCT cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg02458000 chr6:26745757 NA 0.51 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs639012 0.582 rs1898895 chr11:85837669 T/C cg07180834 chr11:85838833 NA -0.33 -4.71 -0.39 6.61e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1008375 0.966 rs4515155 chr4:17696477 G/T cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2404602 0.735 rs4886798 chr15:76673226 A/G cg22467129 chr15:76604101 ETFA -0.52 -5.5 -0.44 2.08e-7 Blood metabolite levels; TGCT cis rs2688608 0.967 rs9971040 chr10:75661162 G/C cg19442545 chr10:75533431 FUT11 -0.3 -4.83 -0.4 3.88e-6 Inflammatory bowel disease; TGCT cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs12780845 0.522 rs17464824 chr10:17210822 A/C cg01003015 chr10:17271136 VIM -0.59 -5.41 -0.44 3.16e-7 Homocysteine levels; TGCT cis rs9859260 0.710 rs366268 chr3:195782177 A/G cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs617219 0.710 rs10805925 chr5:78539399 A/G cg23987322 chr5:78407566 BHMT 0.34 4.48 0.37 1.64e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs11190604 1.000 rs2295780 chr10:102305965 A/G cg16342193 chr10:102329863 NA -0.43 -5.44 -0.44 2.71e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs2033711 0.654 rs734380 chr19:58898963 A/C cg13877915 chr19:58951672 ZNF132 0.65 6.37 0.5 3.36e-9 Uric acid clearance; TGCT cis rs2230307 0.656 rs1395332 chr1:100503993 A/C cg24955406 chr1:100503596 HIAT1 0.74 4.86 0.4 3.41e-6 Carotid intima media thickness; TGCT trans rs4650994 0.967 rs4650998 chr1:178531850 G/A cg05059571 chr16:84539110 KIAA1609 -0.4 -7.39 -0.55 1.94e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs700651 0.789 rs10190226 chr2:198901564 A/G cg00792783 chr2:198669748 PLCL1 -0.55 -4.86 -0.4 3.46e-6 Intracranial aneurysm; TGCT cis rs7511006 1.000 rs5771109 chr22:50678571 T/C cg16473166 chr22:50639996 SELO 0.61 6.1 0.48 1.27e-8 Obesity-related traits; TGCT cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.91 9.53 0.65 1.78e-16 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.888 rs6011559 chr20:61675620 C/T cg08045932 chr20:61659980 NA -0.47 -7.62 -0.56 5.73e-12 Prostate cancer (SNP x SNP interaction); TGCT cis rs7959452 0.605 rs12819406 chr12:69696400 G/T cg20891283 chr12:69753455 YEATS4 0.66 6.57 0.51 1.26e-9 Blood protein levels; TGCT cis rs7267979 1.000 rs1047171 chr20:25428786 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3858526 0.635 rs2045046 chr11:5875867 A/C cg13902645 chr11:5959945 NA -0.49 -5.08 -0.42 1.33e-6 DNA methylation (variation); TGCT cis rs13108904 0.560 rs11247994 chr4:1343720 G/A cg13395646 chr4:1353034 KIAA1530 -0.59 -8.0 -0.58 7.57e-13 Obesity-related traits; TGCT trans rs7819412 0.634 rs4841485 chr8:10909936 T/C cg06636001 chr8:8085503 FLJ10661 0.73 7.2 0.54 5.06e-11 Triglycerides; TGCT cis rs826838 1.000 rs6582619 chr12:38729904 A/G cg13010199 chr12:38710504 ALG10B 0.83 6.88 0.53 2.58e-10 Heart rate; TGCT cis rs2282802 0.685 rs7730245 chr5:139628163 C/A cg01081189 chr5:139537190 NA 0.29 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs1055129 0.681 rs7221792 chr17:73834690 T/G cg08125733 chr17:73851984 WBP2 0.56 5.07 0.41 1.44e-6 White matter hyperintensity burden; TGCT cis rs986417 1.000 rs1254255 chr14:60831342 G/A cg27398547 chr14:60952738 C14orf39 -1.37 -8.31 -0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs10089 0.953 rs2016015 chr5:127527253 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.83 8.09 0.59 4.7e-13 Ileal carcinoids; TGCT cis rs10435719 0.902 rs7459983 chr8:11807221 T/C cg02840367 chr8:11660030 FDFT1 -0.53 -4.51 -0.38 1.5e-5 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs5769707 0.967 rs9616701 chr22:50025546 G/A cg20744362 chr22:50050164 C22orf34 0.27 4.57 0.38 1.18e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs12477438 0.834 rs10179043 chr2:99687490 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.65 -5.8 -0.46 5.16e-8 Chronic sinus infection; TGCT cis rs709400 0.663 rs62007718 chr14:103940436 G/A cg12935359 chr14:103987150 CKB -0.37 -5.69 -0.46 8.55e-8 Body mass index; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg26354017 chr1:205819088 PM20D1 0.56 6.56 0.51 1.31e-9 Menarche (age at onset); TGCT cis rs8038465 0.568 rs62004592 chr15:73878019 A/G cg15420318 chr15:73925796 NPTN 0.64 6.8 0.52 3.9e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6500602 0.627 rs709632 chr16:4587811 C/G cg06139259 chr16:4526053 HMOX2;NMRAL1 -0.26 -4.76 -0.39 5.38e-6 Schizophrenia; TGCT cis rs10493773 0.609 rs11161651 chr1:86177816 A/G cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.16 -0.59 3.27e-13 Urate levels in overweight individuals; TGCT cis rs9443645 0.869 rs10943609 chr6:79676328 A/T cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.3e-7 Intelligence (multi-trait analysis); TGCT cis rs5750830 0.597 rs4821889 chr22:39777254 T/C cg11247378 chr22:39784982 NA -0.68 -9.79 -0.66 4.06e-17 Intelligence (multi-trait analysis); TGCT cis rs9486719 0.843 rs2499796 chr6:96848364 A/G cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs7017914 0.967 rs13274381 chr8:71765094 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.23e-6 Bone mineral density; TGCT cis rs8180040 0.726 rs9843075 chr3:47195630 A/G cg27129171 chr3:47204927 SETD2 0.66 7.79 0.57 2.35e-12 Colorectal cancer; TGCT cis rs10782582 0.586 rs1856791 chr1:76308942 C/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs6967414 0.681 rs2881352 chr7:6753511 T/A cg09896999 chr7:6746977 ZNF12 -0.57 -6.43 -0.5 2.5e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs7666738 0.747 rs2865955 chr4:99040518 A/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs3733585 0.673 rs4697914 chr4:9952266 G/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.63 -0.51 9.3e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs13134216 chr4:98919765 C/T cg05340658 chr4:99064831 C4orf37 0.53 6.11 0.48 1.21e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs75059851 0.756 rs11223650 chr11:133840647 A/G cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs7208859 0.573 rs216443 chr17:28931871 A/G cg14008862 chr17:28927542 LRRC37B2 0.87 5.31 0.43 4.8e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11203032 0.831 rs10887922 chr10:90930236 G/A cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs1949733 1.000 rs2140337 chr4:8502112 A/G cg13073564 chr4:8508604 NA -0.47 -5.05 -0.41 1.55e-6 Response to antineoplastic agents; TGCT cis rs1801251 0.778 rs778340 chr2:233734083 C/T cg08000102 chr2:233561755 GIGYF2 -0.44 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs1371867 1.000 rs1371867 chr8:101330209 A/C cg06636551 chr8:101224915 SPAG1 -0.36 -4.82 -0.4 4.2e-6 Atrioventricular conduction; TGCT cis rs7267979 1.000 rs2257988 chr20:25270003 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2303745 0.589 rs1864115 chr19:17393327 G/C cg04248312 chr19:17393744 ANKLE1 -0.33 -5.55 -0.45 1.62e-7 Systemic lupus erythematosus; TGCT cis rs6952808 0.582 rs871925 chr7:2047875 G/A cg22963979 chr7:1858916 MAD1L1 0.46 7.4 0.55 1.81e-11 Bipolar disorder and schizophrenia; TGCT cis rs11098499 0.820 rs28535956 chr4:120536858 C/T cg09307838 chr4:120376055 NA -0.66 -6.16 -0.48 9.55e-9 Corneal astigmatism; TGCT cis rs9611565 0.512 rs139566 chr22:42199277 A/G cg03806693 chr22:41940476 POLR3H -1.02 -10.21 -0.68 4.01e-18 Vitiligo; TGCT cis rs593982 1.000 rs576663 chr11:65498942 G/T cg08755490 chr11:65554678 OVOL1 1.42 12.09 0.74 1.03e-22 Atopic dermatitis; TGCT cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.62e-9 Blood metabolite levels; TGCT cis rs7760949 0.963 rs9382681 chr6:13915051 A/G cg27413430 chr6:13925136 RNF182 0.59 5.62 0.45 1.21e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg07636037 chr3:49044803 WDR6 0.88 9.28 0.64 6.89e-16 Menarche (age at onset); TGCT cis rs1801251 1.000 rs283479 chr2:233648754 A/G cg25237894 chr2:233734115 C2orf82 0.28 4.82 0.4 4.05e-6 Coronary artery disease; TGCT cis rs2361718 0.500 rs4889970 chr17:78096086 C/T cg09238746 chr17:78121135 EIF4A3 1.08 9.94 0.67 1.82e-17 Yeast infection; TGCT cis rs6490294 0.748 rs111752063 chr12:112297450 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.43 0.44 2.85e-7 Mean platelet volume; TGCT cis rs12681287 0.547 rs6471360 chr8:87513469 C/T cg19078186 chr8:87526527 CPNE3 0.37 4.57 0.38 1.15e-5 Caudate activity during reward; TGCT cis rs2594989 0.943 rs62245869 chr3:11439820 G/A cg00170343 chr3:11313890 ATG7 0.71 5.23 0.43 6.98e-7 Circulating chemerin levels; TGCT cis rs1371867 0.846 rs924057 chr8:101266157 A/G cg06002616 chr8:101225028 SPAG1 0.53 6.42 0.5 2.67e-9 Atrioventricular conduction; TGCT cis rs739496 0.579 rs6489818 chr12:112310580 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.69e-8 Platelet count; TGCT cis rs881375 1.000 rs4323544 chr9:123647377 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.38 0.44 3.52e-7 Rheumatoid arthritis; TGCT cis rs669446 0.562 rs4660260 chr1:44195353 A/G cg12908607 chr1:44402522 ARTN -0.63 -7.39 -0.55 1.88e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs936229 0.954 rs936230 chr15:75145098 C/T cg10253484 chr15:75165896 SCAMP2 0.8 7.17 0.54 5.86e-11 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs8103278 1.000 rs8108590 chr19:46301620 A/G cg11657440 chr19:46296263 DMWD -0.6 -5.78 -0.46 5.75e-8 Coronary artery disease; TGCT cis rs7937682 0.961 rs4936682 chr11:111629743 T/G cg09085632 chr11:111637200 PPP2R1B 1.14 11.53 0.72 2.4e-21 Primary sclerosing cholangitis; TGCT cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9914544 1.000 rs59682951 chr17:18800766 G/T cg26378065 chr17:18585709 ZNF286B 0.54 4.85 0.4 3.62e-6 Educational attainment (years of education); TGCT cis rs1218582 0.596 rs11264275 chr1:154825270 G/T cg09359103 chr1:154839909 KCNN3 0.53 8.49 0.61 5.38e-14 Prostate cancer; TGCT cis rs8180040 1.000 rs2159400 chr3:47375890 T/C cg27129171 chr3:47204927 SETD2 -0.7 -8.63 -0.61 2.53e-14 Colorectal cancer; TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs826838 1.000 rs11183469 chr12:38752311 G/A cg13010199 chr12:38710504 ALG10B 0.82 6.86 0.52 2.91e-10 Heart rate; TGCT cis rs367943 0.966 rs444322 chr5:112815399 C/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs4455778 0.757 rs1072376 chr7:49011373 A/C cg26309511 chr7:48887640 NA -0.48 -5.92 -0.47 2.89e-8 Lung cancer in never smokers; TGCT cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg20203395 chr5:56204925 C5orf35 -0.76 -5.84 -0.46 4.26e-8 Initial pursuit acceleration; TGCT cis rs1670533 0.932 rs610218 chr4:1080083 C/G cg20887711 chr4:1340912 KIAA1530 0.7 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs9467711 0.606 rs9379857 chr6:26367654 G/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs911555 0.755 rs4143998 chr14:103955247 T/C cg12935359 chr14:103987150 CKB -0.33 -4.59 -0.38 1.07e-5 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.03 0.41 1.71e-6 Menopause (age at onset); TGCT cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg11644478 chr21:40555479 PSMG1 0.61 5.72 0.46 7.44e-8 Cognitive function; TGCT cis rs9611565 0.546 rs5758431 chr22:42109917 A/G cg17554472 chr22:41940697 POLR3H 0.48 5.17 0.42 9e-7 Vitiligo; TGCT cis rs6840360 0.582 rs1372976 chr4:152451453 G/A cg17479576 chr4:152424074 FAM160A1 -0.62 -6.7 -0.52 6.65e-10 Intelligence (multi-trait analysis); TGCT cis rs11677370 0.603 rs1454242 chr2:3848532 G/A cg17052675 chr2:3827356 NA -0.42 -7.13 -0.54 7.31e-11 Type 2 diabetes; TGCT cis rs17102423 0.755 rs8009714 chr14:65573446 G/T cg11161011 chr14:65562177 MAX -0.54 -7.49 -0.56 1.15e-11 Obesity-related traits; TGCT cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg13695892 chr22:41940480 POLR3H 0.92 9.06 0.63 2.36e-15 Vitiligo; TGCT cis rs5750830 0.569 rs5750809 chr22:39791491 T/G cg24399712 chr22:39784796 NA -1.06 -12.55 -0.75 8.19e-24 Intelligence (multi-trait analysis); TGCT cis rs3772130 0.962 rs9841595 chr3:121483326 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs3820068 0.581 rs67806552 chr1:15927138 T/C cg05660106 chr1:15850417 CASP9 0.74 7.27 0.55 3.53e-11 Systolic blood pressure; TGCT cis rs1153858 1.000 rs1613559 chr15:45622116 A/G cg14582100 chr15:45693742 SPATA5L1 0.47 5.59 0.45 1.39e-7 Homoarginine levels; TGCT cis rs9325144 0.555 rs28738714 chr12:38706912 G/A cg26384229 chr12:38710491 ALG10B -0.67 -6.17 -0.48 9.08e-9 Morning vs. evening chronotype; TGCT cis rs1075232 0.579 rs58156651 chr15:31749067 C/A cg01030201 chr15:31746330 NA -0.93 -5.51 -0.44 1.98e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs6570726 0.791 rs12208019 chr6:145935572 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.69 0.66 7.3e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7258465 0.931 rs8107347 chr19:18612748 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs3749237 0.576 rs62259939 chr3:49386047 G/A cg07636037 chr3:49044803 WDR6 0.66 6.27 0.49 5.41e-9 Resting heart rate; TGCT cis rs9926296 0.712 rs2434872 chr16:89716915 C/G cg01097406 chr16:89675127 NA 0.36 6.22 0.49 6.91e-9 Vitiligo; TGCT cis rs1552244 0.554 rs28667821 chr3:10050767 A/G cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs57221529 0.709 rs72707023 chr5:667620 G/A cg16624210 chr5:671434 TPPP 0.42 4.82 0.4 4.2e-6 Lung disease severity in cystic fibrosis; TGCT cis rs6582630 0.519 rs12368889 chr12:38315160 G/A cg13010199 chr12:38710504 ALG10B 0.61 4.81 0.4 4.2e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4891159 0.790 rs72975929 chr18:74144630 G/C cg24786174 chr18:74118243 ZNF516 -0.53 -7.07 -0.54 9.9e-11 Longevity; TGCT cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT cis rs62055045 0.656 rs12102284 chr16:71439049 G/A cg09204302 chr16:70713462 MTSS1L -0.31 -4.52 -0.38 1.4e-5 Schizophrenia; TGCT cis rs9527 0.615 rs11191485 chr10:104729816 G/C cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs9467773 1.000 rs9393732 chr6:26530898 G/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs8020441 1.000 rs72681673 chr14:51171922 G/A cg04730355 chr14:51134070 SAV1 0.74 6.12 0.48 1.16e-8 Cognitive performance; TGCT cis rs2295359 0.892 rs2064689 chr1:67653010 G/A cg08029281 chr1:67600428 NA 0.4 4.68 0.39 7.42e-6 Psoriasis; TGCT cis rs67311347 1.000 rs6762997 chr3:40478151 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs35771425 0.619 rs7529900 chr1:211442661 C/T cg26515805 chr1:211431828 RCOR3 -0.44 -4.65 -0.39 8.52e-6 Educational attainment (years of education); TGCT cis rs12477438 0.834 rs1563106 chr2:99701381 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.92 -9.58 -0.65 1.29e-16 Chronic sinus infection; TGCT cis rs3796352 0.881 rs34238610 chr3:53026480 A/T cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1865760 0.516 rs9295684 chr6:26069669 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.45 0.56 1.42e-11 Height; TGCT trans rs66573146 0.656 rs66517061 chr4:6935163 C/G cg07817883 chr1:32538562 TMEM39B 1.53 7.24 0.55 4.06e-11 Granulocyte percentage of myeloid white cells; TGCT cis rs9611565 1.000 rs5758314 chr22:41762523 T/G cg03806693 chr22:41940476 POLR3H -0.89 -9.43 -0.65 3.09e-16 Vitiligo; TGCT cis rs8072100 0.764 rs4794371 chr17:45627693 G/C cg08085267 chr17:45401833 C17orf57 0.45 4.98 0.41 2.09e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs910187 0.605 rs6124960 chr20:45803866 G/C cg27589058 chr20:45804311 EYA2 -0.37 -8.15 -0.59 3.35e-13 Migraine; TGCT cis rs7178572 1.000 rs1565756 chr15:77741640 G/A cg22256960 chr15:77711686 NA -0.97 -11.06 -0.7 3.31e-20 Type 2 diabetes; TGCT cis rs1790761 0.501 rs4930210 chr11:67404726 G/T cg08355456 chr11:67383691 NA -0.33 -5.26 -0.43 6.09e-7 Mean corpuscular volume; TGCT cis rs1865760 0.532 rs9295687 chr6:26082710 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs1483890 0.642 rs1843050 chr3:69403918 C/T cg22125112 chr3:69402811 FRMD4B -0.29 -4.97 -0.41 2.15e-6 Resting heart rate; TGCT cis rs1857353 0.901 rs74089244 chr1:75899838 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs9894429 0.789 rs7219915 chr17:79591813 C/T cg21028142 chr17:79581711 NPLOC4 0.3 7.03 0.53 1.2e-10 Eye color traits; TGCT cis rs1372520 0.873 rs2737026 chr4:90779823 A/G cg01966878 chr4:90757139 SNCA -0.3 -4.77 -0.39 5.1e-6 Neuroticism; TGCT cis rs7264396 0.635 rs6058378 chr20:34546658 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs1008375 1.000 rs2159583 chr4:17658838 T/C cg18681998 chr4:17616180 MED28 1.01 11.93 0.73 2.54e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9325144 0.505 rs10785560 chr12:38636622 C/T cg26384229 chr12:38710491 ALG10B 0.73 7.08 0.54 9.4e-11 Morning vs. evening chronotype; TGCT cis rs9811920 0.931 rs7629487 chr3:99860401 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.41 -4.66 -0.39 8.01e-6 Axial length; TGCT cis rs7428 0.502 rs3184781 chr2:85549527 T/C cg24342717 chr2:85555507 TGOLN2 -0.48 -8.29 -0.6 1.6e-13 Ear protrusion; TGCT cis rs2153535 0.580 rs7453115 chr6:8447261 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs4733781 0.527 rs11774633 chr8:131190243 C/T cg16277922 chr8:131349729 ASAP1 0.36 4.97 0.41 2.13e-6 Tuberculosis; TGCT cis rs9443645 0.870 rs9350799 chr6:79723651 C/A cg09184832 chr6:79620586 NA -0.45 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.562 rs10458225 chr6:8386004 G/A cg23788917 chr6:8435910 SLC35B3 -0.65 -5.92 -0.47 2.92e-8 Motion sickness; TGCT cis rs875971 0.964 rs12668936 chr7:65914404 C/T cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg11890956 chr21:40555474 PSMG1 1.12 12.45 0.75 1.39e-23 Cognitive function; TGCT cis rs4803468 0.934 rs11880674 chr19:41889423 A/T cg09537434 chr19:41945824 ATP5SL -0.9 -10.06 -0.67 9.09e-18 Height; TGCT cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg13695892 chr22:41940480 POLR3H -0.88 -8.63 -0.61 2.45e-14 Vitiligo; TGCT cis rs4664308 0.935 rs4520993 chr2:160937673 G/A cg03641300 chr2:160917029 PLA2R1 -0.28 -6.83 -0.52 3.43e-10 Idiopathic membranous nephropathy; TGCT cis rs35306767 0.807 rs12768348 chr10:899224 T/G cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs4455778 0.691 rs10229690 chr7:49003172 A/G cg26309511 chr7:48887640 NA -0.5 -5.96 -0.47 2.45e-8 Lung cancer in never smokers; TGCT cis rs9788333 0.962 rs61951450 chr13:21886354 G/A cg22663859 chr13:21900854 NA 0.36 4.99 0.41 1.97e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs12477438 0.834 rs11903311 chr2:99701807 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.69 -6.1 -0.48 1.28e-8 Chronic sinus infection; TGCT cis rs11112613 0.713 rs11112588 chr12:105943801 A/C cg03607813 chr12:105948248 NA 0.48 5.5 0.44 2.04e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs3617 0.625 rs11715347 chr3:52883070 C/T cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4700695 0.719 rs27087 chr5:65453050 G/A cg21114390 chr5:65439923 SFRS12 -0.84 -7.33 -0.55 2.58e-11 Facial morphology (factor 19); TGCT cis rs9291683 0.588 rs12647117 chr4:10022059 T/C cg00071950 chr4:10020882 SLC2A9 0.7 9.52 0.65 1.86e-16 Bone mineral density; TGCT cis rs6740731 0.518 rs13034331 chr2:145293097 A/G cg07679370 chr2:145795797 NA -0.26 -5.07 -0.41 1.43e-6 Coronary artery disease; TGCT cis rs910316 0.692 rs7156586 chr14:75506230 A/T cg08847533 chr14:75593920 NEK9 0.7 6.64 0.51 8.92e-10 Height; TGCT cis rs477895 0.653 rs66648159 chr11:63899429 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.27 0.49 5.58e-9 Mean platelet volume; TGCT cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg08280861 chr8:58055591 NA 0.46 5.19 0.42 8.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg03060546 chr3:49711283 APEH 0.51 4.91 0.4 2.84e-6 Menarche (age at onset); TGCT cis rs2180341 0.824 rs9321076 chr6:127655614 G/A cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg08219700 chr8:58056026 NA 0.3 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs826838 0.904 rs10876086 chr12:39188208 C/A cg13010199 chr12:38710504 ALG10B 0.77 6.09 0.48 1.31e-8 Heart rate; TGCT cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs10256972 0.721 rs10435145 chr7:1065988 C/T cg09174653 chr7:1063357 C7orf50;MIR339 -0.24 -4.89 -0.4 3.12e-6 Longevity;Endometriosis; TGCT cis rs71636778 0.509 rs35969145 chr1:27259392 G/A cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs1577917 0.696 rs2842617 chr6:86309698 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.55 -5.03 -0.41 1.68e-6 Response to antipsychotic treatment; TGCT cis rs17376456 0.877 rs10066791 chr5:93350255 G/T cg21475434 chr5:93447410 FAM172A 0.62 4.94 0.41 2.52e-6 Diabetic retinopathy; TGCT cis rs6570726 0.516 rs10457779 chr6:145736663 C/T cg23711669 chr6:146136114 FBXO30 0.61 5.42 0.44 3.05e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs11690935 0.959 rs13419987 chr2:172623914 T/C cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs13108904 0.967 rs4405964 chr4:1278814 A/G cg03303774 chr4:1407052 NA 0.31 4.87 0.4 3.31e-6 Obesity-related traits; TGCT cis rs7819412 0.807 rs4840542 chr8:10944809 G/T cg21775007 chr8:11205619 TDH -0.53 -4.9 -0.4 2.93e-6 Triglycerides; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.85 0.4 3.59e-6 Lymphocyte counts; TGCT cis rs6840360 0.642 rs2724551 chr4:152355383 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs916888 0.821 rs70600 chr17:44860021 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.7 4.82 0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg01802117 chr1:53393560 SCP2 -0.45 -5.28 -0.43 5.53e-7 Monocyte count; TGCT cis rs11792861 0.888 rs75543406 chr9:111816903 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.52 0.38 1.44e-5 Menarche (age at onset); TGCT cis rs10875595 0.509 rs115819920 chr5:140663745 A/C cg20560182 chr5:140700478 TAF7 -0.66 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg02458000 chr6:26745757 NA -0.51 -4.57 -0.38 1.18e-5 Schizophrenia; TGCT cis rs6586111 1.000 rs7067994 chr10:82373459 A/G cg03086067 chr10:82368399 SH2D4B -0.24 -4.7 -0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs2153535 0.541 rs7774752 chr6:8468978 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs854765 0.583 rs8080823 chr17:17864048 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.86 0.58 1.58e-12 Total body bone mineral density; TGCT cis rs6448317 0.520 rs13116411 chr4:24928949 G/A cg21108841 chr4:24914750 CCDC149 -0.75 -7.18 -0.54 5.7e-11 Heschl's gyrus morphology; TGCT cis rs7959452 0.535 rs11177577 chr12:69671791 C/T cg11871910 chr12:69753446 YEATS4 0.63 6.24 0.49 6.36e-9 Blood protein levels; TGCT cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs9660180 0.868 rs72634846 chr1:1704915 C/G cg03396347 chr1:1875803 NA -0.36 -6.58 -0.51 1.19e-9 Body mass index; TGCT cis rs4850410 0.554 rs7575709 chr2:197914758 C/A cg19149314 chr2:197065128 HECW2 0.23 4.51 0.38 1.47e-5 Interferon alpha levels in systemic lupus erythematosus; TGCT cis rs7647973 0.626 rs4855849 chr3:49653378 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs986417 0.748 rs10133403 chr14:60945298 C/T cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs763121 0.853 rs4821816 chr22:39113134 G/A cg06022373 chr22:39101656 GTPBP1 0.75 7.39 0.55 1.92e-11 Menopause (age at onset); TGCT cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg09323728 chr8:95962352 TP53INP1 -0.54 -7.03 -0.53 1.23e-10 Type 2 diabetes; TGCT cis rs873946 0.586 rs3829130 chr10:134563122 C/T cg26818010 chr10:134567672 INPP5A -0.35 -4.76 -0.39 5.21e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2050392 0.861 rs303448 chr10:30727084 G/T cg13289132 chr10:30722225 MAP3K8 -0.41 -4.97 -0.41 2.15e-6 Inflammatory bowel disease; TGCT cis rs60843830 1.000 rs60843830 chr2:286756 C/G cg25945732 chr2:264204 ACP1;SH3YL1 0.74 7.12 0.54 7.67e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs79057730 0.599 rs4333501 chr7:803244 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.76 5.84 0.46 4.31e-8 Initial pursuit acceleration; TGCT cis rs7264396 0.635 rs6060703 chr20:34529906 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs7178424 0.541 rs2899678 chr15:62324723 A/G cg00456672 chr15:62358751 C2CD4A -0.29 -4.46 -0.37 1.84e-5 Height; TGCT cis rs6089829 0.851 rs4809460 chr20:61661355 T/C cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs4906332 1.000 rs1951389 chr14:103898525 G/C cg26031613 chr14:104095156 KLC1 -0.52 -4.59 -0.38 1.08e-5 Coronary artery disease; TGCT cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs7772486 0.597 rs9386136 chr6:146158300 A/T cg05347473 chr6:146136440 FBXO30 0.66 6.2 0.49 7.84e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs651907 0.535 rs34648996 chr3:101511202 A/G cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg10560079 chr2:191398806 TMEM194B 0.42 5.83 0.46 4.52e-8 Pulse pressure; TGCT cis rs10504229 0.595 rs116490935 chr8:58117531 A/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs7216064 1.000 rs9915108 chr17:65874463 T/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4285028 0.948 rs7651226 chr3:121670802 G/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs2153535 0.580 rs2184586 chr6:8474182 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs3125734 0.633 rs4979774 chr10:63967795 A/T cg09941381 chr10:64027924 RTKN2 -0.36 -5.61 -0.45 1.23e-7 Rheumatoid arthritis; TGCT cis rs137603 0.623 rs137657 chr22:39733242 G/T cg01093212 chr22:39715156 SNORD43;RPL3 -0.52 -5.09 -0.42 1.29e-6 Primary biliary cholangitis; TGCT cis rs8038465 0.615 rs11072430 chr15:73981701 A/G cg15420318 chr15:73925796 NPTN -0.7 -7.76 -0.57 2.71e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12753569 1.000 rs12753569 chr1:76484014 G/T cg00791851 chr1:76518896 NA -0.35 -4.57 -0.38 1.17e-5 Personality dimensions; TGCT cis rs2153535 0.580 rs6910742 chr6:8448328 G/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT trans rs114540395 0.777 rs114076639 chr10:103333323 G/A cg10198749 chr1:39920707 MACF1 0.55 7.06 0.54 1.06e-10 Schizophrenia; TGCT cis rs6582630 0.555 rs1829583 chr12:38423161 T/C cg26384229 chr12:38710491 ALG10B -0.8 -7.45 -0.56 1.42e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7772486 0.686 rs9376956 chr6:145949844 T/C cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs35306767 0.623 rs72760941 chr10:1141244 A/G cg20503657 chr10:835505 NA 0.51 5.41 0.44 3.18e-7 Eosinophil percentage of granulocytes; TGCT cis rs6912958 0.781 rs7750207 chr6:88303967 A/C cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -5.22 -0.42 7.36e-7 Monocyte percentage of white cells; TGCT trans rs1814175 0.765 rs1721990 chr11:49912154 G/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.12e-10 Height; TGCT cis rs9926296 0.533 rs12102290 chr16:89812617 C/T cg27121462 chr16:89883253 FANCA 0.82 8.95 0.63 4.3e-15 Vitiligo; TGCT cis rs7412746 0.524 rs58304714 chr1:150831561 T/A cg04414720 chr1:150670196 GOLPH3L 0.39 4.75 0.39 5.55e-6 Melanoma; TGCT trans rs797680 0.856 rs7537403 chr1:93777724 T/C cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6671200 1.000 rs933107 chr1:95672229 C/T cg03123541 chr1:95699097 RWDD3 -0.87 -6.17 -0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs12477438 0.765 rs6749059 chr2:99591021 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.66 -0.61 2.13e-14 Chronic sinus infection; TGCT cis rs950169 0.887 rs3860265 chr15:84945185 C/T cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs801193 1.000 rs3778909 chr7:66255646 G/C cg00343986 chr7:65444356 GUSB 0.23 5.13 0.42 1.08e-6 Aortic root size; TGCT cis rs67311347 0.955 rs73080163 chr3:40533061 G/T cg17264618 chr3:40429014 ENTPD3 0.33 4.44 0.37 1.98e-5 Renal cell carcinoma; TGCT cis rs7829975 0.539 rs4841012 chr8:8551710 C/A cg15556689 chr8:8085844 FLJ10661 -0.54 -4.61 -0.38 1e-5 Mood instability; TGCT cis rs4822044 0.568 rs1883370 chr22:42143740 C/A cg03806693 chr22:41940476 POLR3H 1.0 10.02 0.67 1.11e-17 Cannabis dependence symptom count; TGCT cis rs2282802 0.685 rs6869910 chr5:139629450 T/C cg01081189 chr5:139537190 NA 0.27 4.84 0.4 3.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2970818 0.831 rs7304949 chr12:4609625 A/G cg06654103 chr12:4920613 KCNA6 0.19 4.53 0.38 1.39e-5 Phosphorus levels; TGCT trans rs6089829 0.962 rs6062777 chr20:61663748 G/A cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.584 rs7548832 chr1:53193576 A/T cg24675658 chr1:53192096 ZYG11B -0.86 -10.85 -0.7 1.07e-19 Monocyte count; TGCT cis rs7666738 0.861 rs10018654 chr4:99002226 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6121246 0.529 rs6060118 chr20:30171209 T/C cg10886678 chr20:30946050 ASXL1 -0.67 -4.52 -0.38 1.41e-5 Mean corpuscular hemoglobin; TGCT cis rs950169 0.922 rs11635505 chr15:85097034 A/C cg17173187 chr15:85201210 NMB -0.54 -5.84 -0.46 4.2e-8 Schizophrenia; TGCT cis rs9896933 0.830 rs607544 chr17:80768760 C/G cg20578329 chr17:80767326 TBCD -0.34 -4.97 -0.41 2.16e-6 Bone mineral accretion in asthma (oral corticosteroid dose interaction); TGCT cis rs12048904 0.505 rs11166508 chr1:101233511 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.69 -5.58 -0.45 1.41e-7 Multiple sclerosis; TGCT cis rs6430585 0.759 rs4954623 chr2:136535876 G/A cg07169764 chr2:136633963 MCM6 -1.19 -11.11 -0.71 2.49e-20 Corneal structure; TGCT cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg02458000 chr6:26745757 NA 0.5 4.65 0.39 8.2e-6 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Vitiligo; TGCT cis rs2688608 0.967 rs72814394 chr10:75656325 C/T cg19442545 chr10:75533431 FUT11 -0.29 -4.71 -0.39 6.5e-6 Inflammatory bowel disease; TGCT cis rs10791097 0.739 rs4936120 chr11:130723452 G/A cg12179176 chr11:130786555 SNX19 0.75 8.62 0.61 2.66e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3008870 0.755 rs2815374 chr1:67507387 G/A cg11518657 chr1:67396239 MIER1 0.48 4.51 0.38 1.49e-5 Lymphocyte percentage of white cells; TGCT cis rs9303401 0.614 rs66480139 chr17:57101538 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.83 0.46 4.4e-8 Cognitive test performance; TGCT cis rs11785400 1.000 rs4266629 chr8:143736635 A/G cg10596483 chr8:143751796 JRK 0.55 6.0 0.47 2.04e-8 Schizophrenia; TGCT cis rs12908161 1.000 rs11637142 chr15:85295927 A/G cg11189052 chr15:85197271 WDR73 0.71 5.89 0.47 3.35e-8 Schizophrenia; TGCT cis rs12900413 0.603 rs12906832 chr15:90301314 C/G cg24249390 chr15:90295951 MESP1 -0.3 -5.23 -0.42 7.05e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2832191 0.935 rs11910316 chr21:30519729 G/A cg08807101 chr21:30365312 RNF160 -0.53 -4.94 -0.41 2.49e-6 Dental caries; TGCT cis rs12497850 0.863 rs4858799 chr3:48728204 G/C cg16497277 chr3:49208875 KLHDC8B -0.5 -4.78 -0.39 4.87e-6 Parkinson's disease; TGCT cis rs10465746 0.967 rs11163879 chr1:84444051 T/C cg10977910 chr1:84465055 TTLL7 0.65 6.54 0.51 1.44e-9 Obesity-related traits; TGCT cis rs9788682 0.747 rs2656073 chr15:78742276 G/T cg24631222 chr15:78858424 CHRNA5 0.64 4.93 0.4 2.6e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2677744 0.626 rs2001216 chr15:91498130 T/C cg23684204 chr15:91497937 RCCD1 0.39 5.92 0.47 2.91e-8 Attention deficit hyperactivity disorder; TGCT cis rs1005277 0.579 rs2472174 chr10:38375382 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -7.88 -0.58 1.44e-12 Extrinsic epigenetic age acceleration; TGCT cis rs9291683 0.595 rs10939665 chr4:10037628 T/C cg11266682 chr4:10021025 SLC2A9 0.64 8.91 0.62 5.31e-15 Bone mineral density; TGCT cis rs2230307 0.536 rs2893426 chr1:100528200 G/T cg24955406 chr1:100503596 HIAT1 0.74 4.86 0.4 3.41e-6 Carotid intima media thickness; TGCT cis rs3751972 0.866 rs8082467 chr17:26253468 G/A cg02948944 chr17:26242737 NA 0.5 6.86 0.52 2.96e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs1862618 0.525 rs832403 chr5:56265992 G/T cg12311346 chr5:56204834 C5orf35 0.79 6.94 0.53 1.98e-10 Initial pursuit acceleration; TGCT cis rs7769051 1.000 rs10484629 chr6:133117870 A/C cg07930552 chr6:133119739 C6orf192 0.94 5.04 0.41 1.6e-6 Type 2 diabetes nephropathy; TGCT cis rs9303401 0.614 rs34550282 chr17:57092788 G/A cg25039879 chr17:56429692 SUPT4H1 0.55 4.93 0.4 2.63e-6 Cognitive test performance; TGCT cis rs12691307 1 rs12691307 chr16:29939877 A/G cg26859862 chr16:30389551 SEPT1 -0.54 -4.61 -0.38 9.91e-6 Schizophrenia; TGCT cis rs10114408 0.877 rs10821245 chr9:96645614 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs3809566 1.000 rs3809566 chr15:63333724 A/G cg08198488 chr15:63333792 TPM1 -0.36 -5.36 -0.43 3.83e-7 Platelet count; TGCT cis rs3125734 0.582 rs7904465 chr10:64002393 G/A cg19640130 chr10:64028056 RTKN2 -0.39 -5.02 -0.41 1.78e-6 Rheumatoid arthritis; TGCT cis rs1256061 0.528 rs10143616 chr14:64740175 G/A cg21174375 chr14:64681225 SYNE2 0.22 4.73 0.39 5.96e-6 Hemoglobin concentration;Red blood cell count;Hematocrit; TGCT cis rs6840360 0.837 rs13146981 chr4:152720703 T/C cg22705602 chr4:152727874 NA 0.25 4.67 0.39 7.76e-6 Intelligence (multi-trait analysis); TGCT cis rs7223966 0.921 rs7225092 chr17:61864005 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3087591 0.615 rs12943365 chr17:29680526 C/G cg24425628 chr17:29625626 OMG;NF1 0.34 4.84 0.4 3.74e-6 Hip circumference; TGCT cis rs4372836 0.930 rs7607844 chr2:28971738 T/A cg09522027 chr2:28974177 PPP1CB -0.59 -4.93 -0.4 2.63e-6 Body mass index; TGCT cis rs3771570 0.901 rs3771587 chr2:242409701 A/G cg21155796 chr2:242212141 HDLBP 0.93 6.69 0.52 6.74e-10 Prostate cancer; TGCT cis rs9486719 0.843 rs2205754 chr6:96843134 T/C cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs9549367 0.713 rs9549357 chr13:113860121 C/T cg18105134 chr13:113819100 PROZ -0.46 -8.5 -0.61 5.06e-14 Platelet distribution width; TGCT cis rs59698941 0.550 rs11739194 chr5:132201230 T/C cg21474247 chr5:131268130 NA 0.31 4.77 0.39 5.01e-6 Apolipoprotein A-IV levels; TGCT cis rs7614311 0.689 rs56329572 chr3:63846672 G/A cg22134162 chr3:63841271 THOC7 -0.42 -4.62 -0.38 9.39e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs28595532 0.920 rs17325017 chr4:119774607 A/G cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs35306767 0.903 rs11253458 chr10:882843 T/C cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs6540559 0.673 rs926346 chr1:209962204 A/T cg21951975 chr1:209979733 IRF6 0.68 5.3 0.43 5.17e-7 Cleft lip with or without cleft palate; TGCT cis rs34172651 0.583 rs200541 chr16:24733141 A/G cg06028605 chr16:24865363 SLC5A11 -0.41 -4.51 -0.38 1.49e-5 Intelligence (multi-trait analysis); TGCT cis rs9325144 0.555 rs7955128 chr12:38684121 A/T cg26384229 chr12:38710491 ALG10B 0.67 6.42 0.5 2.56e-9 Morning vs. evening chronotype; TGCT cis rs7178572 0.889 rs11857450 chr15:77802791 C/G cg22256960 chr15:77711686 NA 0.93 10.91 0.7 7.71e-20 Type 2 diabetes; TGCT cis rs12220898 0.749 rs4838486 chr10:50484962 G/A cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs950027 0.620 rs1153860 chr15:45636584 A/G cg26924012 chr15:45694286 SPATA5L1 -0.79 -8.75 -0.62 1.27e-14 Response to fenofibrate (adiponectin levels); TGCT cis rs60871478 0.636 rs12532761 chr7:905229 C/T cg00475322 chr7:917719 C7orf20 0.52 5.04 0.41 1.58e-6 Cerebrospinal P-tau181p levels; TGCT cis rs10197940 0.624 rs17270233 chr2:152372420 A/G cg19508488 chr2:152266495 RIF1 0.72 6.55 0.51 1.38e-9 Lung cancer; TGCT cis rs1218582 0.772 rs11264282 chr1:154867370 G/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.35 -0.55 2.32e-11 Prostate cancer; TGCT cis rs6570726 0.811 rs375873 chr6:145812371 G/T cg23711669 chr6:146136114 FBXO30 0.73 6.85 0.52 3e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 0.920 rs115690307 chr4:119768289 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs7659604 0.592 rs56077950 chr4:122721412 C/T cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.39 -0.44 3.47e-7 Type 2 diabetes; TGCT cis rs6733011 0.500 rs6755640 chr2:99445917 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.67 -0.39 7.64e-6 Bipolar disorder; TGCT cis rs10501293 0.917 rs7951266 chr11:43110728 C/T cg03447554 chr11:43094025 NA 0.48 6.54 0.51 1.42e-9 Cognitive performance; TGCT cis rs9972944 0.902 rs9972885 chr17:63771264 G/T cg07283582 chr17:63770753 CCDC46 0.29 5.95 0.47 2.54e-8 Total body bone mineral density; TGCT cis rs4665809 0.941 rs2289021 chr2:26362515 A/C cg04944784 chr2:26401820 FAM59B 0.64 5.54 0.45 1.69e-7 Gut microbiome composition (summer); TGCT cis rs2204008 0.846 rs2030416 chr12:38465118 A/G cg26384229 chr12:38710491 ALG10B -0.8 -7.43 -0.56 1.51e-11 Bladder cancer; TGCT cis rs709400 0.627 rs62007686 chr14:103899344 A/G cg26031613 chr14:104095156 KLC1 0.85 9.31 0.64 6e-16 Body mass index; TGCT cis rs7845219 0.555 rs1129152 chr8:95888307 C/T cg13393036 chr8:95962371 TP53INP1 -0.58 -6.99 -0.53 1.46e-10 Type 2 diabetes; TGCT cis rs950776 0.667 rs57728226 chr15:78929350 G/C cg06917634 chr15:78832804 PSMA4 0.61 4.77 0.39 5.17e-6 Sudden cardiac arrest; TGCT cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs3540 0.960 rs2238329 chr15:91028401 G/A cg22089800 chr15:90895588 ZNF774 0.77 7.25 0.55 4.02e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs1552244 0.748 rs9862221 chr3:10059658 G/T cg00149659 chr3:10157352 C3orf10 0.89 5.6 0.45 1.32e-7 Alzheimer's disease; TGCT cis rs4699052 0.662 rs1516731 chr4:104252694 T/C cg16532752 chr4:104119610 CENPE -0.5 -4.92 -0.4 2.71e-6 Testicular germ cell tumor; TGCT cis rs4766566 0.609 rs1344438 chr12:111735954 C/G cg10833066 chr12:111807467 FAM109A 0.39 7.2 0.54 5.07e-11 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs565229 0.777 rs551615 chr11:122135614 C/T cg02159381 chr11:122852523 BSX 0.52 4.62 0.38 9.28e-6 Hemostatic factors and hematological phenotypes; TGCT cis rs9549367 0.789 rs6577031 chr13:113878182 T/C cg18105134 chr13:113819100 PROZ 0.35 5.74 0.46 7.01e-8 Platelet distribution width; TGCT cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs244731 0.959 rs11740250 chr5:176721272 G/C cg17509989 chr5:176798049 RGS14 0.64 7.71 0.57 3.49e-12 Urate levels in lean individuals; TGCT cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 5.03 0.41 1.66e-6 Electroencephalogram traits; TGCT cis rs3733585 0.699 rs62294331 chr4:9959889 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2153535 0.580 rs9378551 chr6:8463744 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs763121 0.853 rs2294296 chr22:39053049 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs9818758 0.882 rs74926817 chr3:49378833 C/G cg00383909 chr3:49044727 WDR6 0.7 4.75 0.39 5.48e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7267979 1.000 rs884613 chr20:25288505 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs16986825 0.570 rs5752822 chr22:29266025 A/G cg02153584 chr22:29168773 CCDC117 0.67 4.5 0.37 1.55e-5 Pancreatic cancer; TGCT cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg13695892 chr22:41940480 POLR3H -0.9 -9.03 -0.63 2.7e-15 Vitiligo; TGCT cis rs6430585 0.528 rs10496738 chr2:136751488 C/T cg07169764 chr2:136633963 MCM6 1.25 12.67 0.75 4.02e-24 Corneal structure; TGCT cis rs3935685 0.874 rs55858810 chr15:78004230 G/T cg03457338 chr15:78040120 NA -0.21 -5.54 -0.45 1.72e-7 Intelligence (multi-trait analysis); TGCT cis rs7940866 0.838 rs10750455 chr11:130800330 C/T cg12179176 chr11:130786555 SNX19 0.63 6.28 0.49 5.3300000000000004e-09 Schizophrenia; TGCT cis rs9796 0.866 rs66818965 chr15:41402279 G/A cg18705301 chr15:41695430 NDUFAF1 -0.47 -6.09 -0.48 1.34e-8 Menopause (age at onset); TGCT cis rs7568458 0.684 rs7593969 chr2:85809670 A/G cg02493740 chr2:85810744 VAMP5 0.31 5.74 0.46 6.73e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7666738 0.830 rs28587201 chr4:98991733 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs586688 0.582 rs1270536 chr1:201670876 A/G cg07139329 chr1:201708558 NAV1 -0.56 -5.67 -0.45 9.65e-8 Obesity-related traits; TGCT cis rs10875746 0.669 rs10783244 chr12:48664989 A/C cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT cis rs523522 0.962 rs4767903 chr12:120930046 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs2456568 0.805 rs55649862 chr11:93682888 G/T cg17595323 chr11:93583763 C11orf90 -0.46 -6.01 -0.47 1.92e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4819052 0.851 rs2838842 chr21:46669217 C/T cg06618935 chr21:46677482 NA -0.36 -5.46 -0.44 2.46e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2066819 1.000 rs76151170 chr12:56659320 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs1395 0.778 rs62128743 chr2:27390169 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.66 8.95 0.63 4.24e-15 Blood metabolite levels; TGCT cis rs7666738 0.830 rs7662199 chr4:99019766 G/A cg17366294 chr4:99064904 C4orf37 0.7 7.34 0.55 2.41e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2066819 1.000 rs17118403 chr12:56630067 C/T cg26714650 chr12:56694279 CS -1.42 -5.7 -0.46 8.43e-8 Psoriasis vulgaris; TGCT cis rs6964587 1.000 rs10274756 chr7:91740796 G/A cg22709100 chr7:91322751 NA 0.28 4.61 0.38 9.79e-6 Breast cancer; TGCT cis rs4629710 0.617 rs28360555 chr6:131538952 C/A cg12606694 chr6:131520996 AKAP7 0.39 4.63 0.38 9.14e-6 Multiple myeloma (IgH translocation); TGCT cis rs9899728 0.706 rs9895516 chr17:73020517 T/C cg00012762 chr17:72744649 SLC9A3R1 -1.0 -4.48 -0.37 1.67e-5 Alzheimer's disease or small vessel stroke; TGCT cis rs3015497 0.663 rs12434932 chr14:51157614 T/C cg04730355 chr14:51134070 SAV1 -0.62 -5.86 -0.47 3.82e-8 Mean platelet volume; TGCT cis rs6867032 0.527 rs4371796 chr5:1977785 C/T cg05184729 chr5:1962311 NA 0.27 4.68 0.39 7.31e-6 Gut microbiome composition (winter); TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg26338869 chr17:61819248 STRADA -0.53 -4.83 -0.4 3.91e-6 Prudent dietary pattern; TGCT cis rs597539 0.652 rs673821 chr11:68678718 G/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.41 0.6 8.4e-14 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9436747 0.641 rs1343982 chr1:66045251 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.65 0.39 8.37e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs35883536 0.528 rs1542837 chr1:101029768 T/C cg06223162 chr1:101003688 GPR88 0.43 8.39 0.6 9.04e-14 Monocyte count; TGCT cis rs1218582 0.741 rs11264291 chr1:154914797 C/T cg03351412 chr1:154909251 PMVK 0.51 4.78 0.39 4.85e-6 Prostate cancer; TGCT cis rs9388451 0.839 rs9321054 chr6:126079968 A/G cg05901451 chr6:126070800 HEY2 1.02 15.34 0.81 2e-30 Brugada syndrome; TGCT cis rs9911578 0.835 rs9889419 chr17:56473259 C/T cg05425664 chr17:57184151 TRIM37 -0.61 -5.88 -0.47 3.6e-8 Intelligence (multi-trait analysis); TGCT cis rs9905704 0.647 rs7221274 chr17:57008128 A/G cg05425664 chr17:57184151 TRIM37 -0.57 -4.44 -0.37 1.97e-5 Testicular germ cell tumor; TGCT trans rs7618501 0.699 rs3733135 chr3:49939587 G/A cg21659725 chr3:3221576 CRBN 0.77 9.15 0.63 1.42e-15 Intelligence (multi-trait analysis); TGCT cis rs2730245 0.528 rs1188954 chr7:158691417 G/A cg24397884 chr7:158709396 WDR60 0.35 4.51 0.38 1.5e-5 Height; TGCT cis rs6088580 0.634 rs6088484 chr20:32985961 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs950169 0.922 rs2033284 chr15:84946273 C/T cg11189052 chr15:85197271 WDR73 0.83 6.48 0.5 1.91e-9 Schizophrenia; TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg01802117 chr1:53393560 SCP2 -0.42 -4.86 -0.4 3.43e-6 Monocyte count; TGCT cis rs9291683 0.546 rs4575994 chr4:9997979 G/A cg11266682 chr4:10021025 SLC2A9 0.61 7.66 0.57 4.53e-12 Bone mineral density; TGCT cis rs514406 0.861 rs1571979 chr1:53237526 G/A cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs2832191 0.716 rs2297252 chr21:30377104 G/A cg08807101 chr21:30365312 RNF160 0.64 6.05 0.48 1.59e-8 Dental caries; TGCT cis rs9581857 0.685 rs11839899 chr13:28041780 G/A cg22138327 chr13:27999177 GTF3A 0.72 4.6 0.38 1.03e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2933343 0.729 rs789230 chr3:128602558 G/A cg11901034 chr3:128598214 ACAD9 -0.68 -6.63 -0.51 9.16e-10 IgG glycosylation; TGCT cis rs13191362 1.000 rs73035025 chr6:163000988 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg27588902 chr6:42928151 GNMT -0.48 -5.66 -0.45 9.82e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7246657 0.722 rs10412510 chr19:38075944 A/G cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs40363 1.000 rs1690441 chr16:3517635 C/G cg22508957 chr16:3507546 NAT15 0.57 5.33 0.43 4.38e-7 Tuberculosis; TGCT cis rs35000415 0.873 rs34748780 chr7:128700153 A/G cg06242719 chr7:129414860 MIR183;MIR96 -0.34 -4.67 -0.39 7.58e-6 Systemic lupus erythematosus; TGCT cis rs3617 0.625 rs2535633 chr3:52859630 C/G cg10802521 chr3:52805072 NEK4 0.6 6.89 0.53 2.46e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs317689 0.581 rs315132 chr12:69761996 G/C cg20891283 chr12:69753455 YEATS4 0.65 5.74 0.46 6.91e-8 Response to diuretic therapy; TGCT cis rs210152 0.588 rs449978 chr6:33496060 G/A cg16739976 chr6:34101401 GRM4 -0.64 -5.27 -0.43 5.8e-7 Schizophrenia; TGCT cis rs514406 0.505 rs7543239 chr1:53162416 A/G cg24675658 chr1:53192096 ZYG11B -0.74 -8.28 -0.6 1.65e-13 Monocyte count; TGCT cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs11754661 1.000 rs11754661 chr6:151207078 G/A cg11579907 chr6:151412213 MTHFD1L 0.47 4.5 0.37 1.53e-5 Alzheimer's disease (late onset); TGCT cis rs78545713 1.000 rs41266821 chr6:26247198 A/G cg12260798 chr6:26240519 HIST1H4F -0.58 -4.89 -0.4 3.06e-6 Iron status biomarkers (total iron binding capacity); TGCT trans rs8073060 0.660 rs34184070 chr17:34003810 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs611744 0.647 rs9969614 chr8:109260581 A/G cg21045802 chr8:109455806 TTC35 0.71 7.21 0.54 4.78e-11 Dupuytren's disease; TGCT cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs3809863 0.646 rs9899121 chr17:45395144 C/T cg08085267 chr17:45401833 C17orf57 -0.69 -8.17 -0.59 2.97e-13 Glaucoma (primary open-angle); TGCT cis rs17473412 0.609 rs1002112 chr5:122872642 G/A cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs28595532 0.920 rs17257945 chr4:119666465 T/A cg11846333 chr4:119757529 SEC24D 0.95 4.9 0.4 2.97e-6 Cannabis dependence symptom count; TGCT cis rs56104184 0.775 rs73061699 chr19:49400511 T/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7666738 0.830 rs890470 chr4:98923435 A/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs546131 0.600 rs7946699 chr11:34820069 G/C cg06937548 chr11:34938143 PDHX;APIP 0.54 4.58 0.38 1.11e-5 Lung disease severity in cystic fibrosis; TGCT trans rs2727020 0.729 rs1917325 chr11:49370004 G/A cg03929089 chr4:120376271 NA -0.74 -8.68 -0.61 1.87e-14 Coronary artery disease; TGCT cis rs77972916 0.505 rs11899984 chr2:43578246 C/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.38 -0.5 3.27e-9 Granulocyte percentage of myeloid white cells; TGCT cis rs295140 1.000 rs12614621 chr2:201171207 G/C cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs5750830 0.649 rs5750818 chr22:39820885 A/G cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg23034840 chr1:205782522 SLC41A1 0.5 4.53 0.38 1.39e-5 Menarche (age at onset); TGCT cis rs6582630 0.634 rs10748443 chr12:38734062 G/T cg26384229 chr12:38710491 ALG10B 0.61 5.65 0.45 1.05e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs8016982 0.674 rs1951614 chr14:81672106 A/G cg01989461 chr14:81687754 GTF2A1 -0.82 -8.49 -0.61 5.31e-14 Schizophrenia; TGCT trans rs6089829 0.962 rs3746747 chr20:61667631 T/C cg17470723 chr8:74884337 TCEB1 0.71 6.79 0.52 4.06e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1801251 1.000 rs2100053 chr2:233719516 G/T cg08000102 chr2:233561755 GIGYF2 -0.63 -6.31 -0.49 4.52e-9 Coronary artery disease; TGCT cis rs7246657 0.663 rs4803276 chr19:38072330 C/A cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.74e-6 Coronary artery calcification; TGCT cis rs1997103 0.954 rs2177809 chr7:55378125 T/C cg17469321 chr7:55412551 NA 0.66 6.94 0.53 1.92e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs67478160 0.595 rs12433109 chr14:104196607 G/A cg26031613 chr14:104095156 KLC1 -0.76 -7.75 -0.57 2.84e-12 Schizophrenia; TGCT cis rs4285028 0.948 rs71329246 chr3:121680170 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs12497850 0.931 rs13064784 chr3:49135961 C/G cg18654377 chr3:49208889 KLHDC8B -0.41 -5.4 -0.44 3.33e-7 Parkinson's disease; TGCT cis rs7762018 0.769 rs4716339 chr6:170063210 C/T cg15984460 chr6:170744215 NA -0.35 -4.47 -0.37 1.71e-5 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs7824557 0.547 rs2409745 chr8:11076635 G/T cg21775007 chr8:11205619 TDH 0.5 4.85 0.4 3.63e-6 Retinal vascular caliber; TGCT cis rs835154 0.845 rs835155 chr5:14875868 A/G cg14843632 chr5:14870594 ANKH -0.35 -4.89 -0.4 3.09e-6 Blood metabolite levels; TGCT cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg26531700 chr6:26746687 NA 0.52 5.01 0.41 1.8e-6 Intelligence (multi-trait analysis); TGCT cis rs17490626 0.568 rs12413529 chr10:71211644 G/T cg12610070 chr10:71211762 TSPAN15 -0.62 -7.15 -0.54 6.52e-11 Thrombosis; TGCT cis rs7923452 0.507 rs612802 chr10:30756441 G/A cg13289132 chr10:30722225 MAP3K8 -0.39 -4.8 -0.4 4.53e-6 Itch intensity from mosquito bite; TGCT cis rs8042680 0.554 rs59902579 chr15:91515489 C/T cg23684204 chr15:91497937 RCCD1 0.36 4.67 0.39 7.75e-6 Type 2 diabetes; TGCT trans rs11764590 0.950 rs55683212 chr7:2078855 G/C cg25206134 chr2:45395956 NA 0.97 7.42 0.55 1.6e-11 Neuroticism; TGCT cis rs10114408 0.959 rs1933674 chr9:96655120 C/T cg13679303 chr9:96623674 NA -0.37 -4.76 -0.39 5.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT trans rs1814175 0.817 rs10769598 chr11:49669326 C/G cg15704280 chr7:45808275 SEPT13 -0.71 -8.22 -0.59 2.27e-13 Height; TGCT cis rs806215 0.950 rs2073561 chr7:127227769 G/C cg25922125 chr7:127225783 GCC1 -0.57 -5.96 -0.47 2.44e-8 Type 2 diabetes; TGCT cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg13395646 chr4:1353034 KIAA1530 -0.39 -4.95 -0.41 2.38e-6 Obesity-related traits; TGCT cis rs4916646 0.668 rs28690226 chr4:11516840 T/C cg16957523 chr4:11431359 HS3ST1 -0.47 -4.66 -0.39 8.08e-6 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg13342137 chr4:2252803 MXD4 0.17 4.44 0.37 1.94e-5 Obesity-related traits; TGCT cis rs6938 0.618 rs11633472 chr15:75184084 T/G cg09165964 chr15:75287851 SCAMP5 0.58 5.33 0.43 4.45e-7 Breast cancer; TGCT cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 1.04 9.22 0.64 9.69e-16 Platelet count; TGCT cis rs13217239 0.646 rs4583981 chr6:26992023 G/T cg15659132 chr6:26577336 NA 0.55 5.53 0.44 1.84e-7 Schizophrenia; TGCT cis rs12908161 1.000 rs35960805 chr15:85343980 T/G cg17173187 chr15:85201210 NMB 0.57 6.39 0.5 3.07e-9 Schizophrenia; TGCT cis rs7246657 0.943 rs10413602 chr19:37891492 T/C cg18154014 chr19:37997991 ZNF793 0.95 6.63 0.51 9.39e-10 Coronary artery calcification; TGCT cis rs1568889 0.887 rs2062269 chr11:28116537 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.35 0.71 6.62e-21 Bipolar disorder; TGCT cis rs78461346 1.000 rs76313267 chr17:80484137 G/A cg15014069 chr17:80540666 FOXK2 0.4 5.03 0.41 1.65e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs10744422 1.000 rs4759382 chr12:123347609 C/T cg25930673 chr12:123319894 HIP1R 0.87 5.21 0.42 7.77e-7 Schizophrenia; TGCT cis rs288326 0.561 rs78528869 chr2:183815502 C/T cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs6089584 0.888 rs6061982 chr20:60620673 C/T cg16423285 chr20:60520624 NA -0.6 -6.41 -0.5 2.76e-9 Body mass index; TGCT cis rs3008870 0.920 rs3008860 chr1:67391003 G/C cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs62064224 0.589 rs4132610 chr17:30801441 C/T cg18200150 chr17:30822561 MYO1D 0.42 5.06 0.41 1.48e-6 Schizophrenia; TGCT cis rs13326165 0.760 rs6763882 chr3:52354772 A/G cg07884673 chr3:53033167 SFMBT1 -0.36 -4.48 -0.37 1.65e-5 HDL cholesterol;HDL cholesterol levels; TGCT trans rs4332037 0.539 rs868754 chr7:2033780 G/C cg25206134 chr2:45395956 NA 0.99 7.09 0.54 9.09e-11 Bipolar disorder; TGCT cis rs4689592 0.503 rs66885632 chr4:7053738 T/C cg26116260 chr4:7069785 GRPEL1 -0.9 -6.76 -0.52 4.9e-10 Monocyte percentage of white cells; TGCT cis rs7809950 1.000 rs28714607 chr7:107106253 T/C cg23024343 chr7:107201750 COG5 -0.33 -5.24 -0.43 6.69e-7 Coronary artery disease; TGCT cis rs60843830 1.000 rs79716074 chr2:277003 A/G cg00108164 chr2:264199 ACP1;SH3YL1 0.7 6.56 0.51 1.33e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9910055 0.529 rs228757 chr17:42164885 G/C cg13607699 chr17:42295918 UBTF -0.64 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT cis rs7917772 0.636 rs2863718 chr10:104519631 G/C cg05855489 chr10:104503620 C10orf26 0.66 5.25 0.43 6.47e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs7819412 0.777 rs1057626 chr8:10962800 T/C cg15556689 chr8:8085844 FLJ10661 -0.71 -6.69 -0.51 6.91e-10 Triglycerides; TGCT cis rs4372836 1.000 rs4372836 chr2:28973883 T/C cg09522027 chr2:28974177 PPP1CB -0.59 -5.15 -0.42 1e-6 Body mass index; TGCT cis rs6940638 0.956 rs12199218 chr6:27025281 T/C cg16898833 chr6:26189333 HIST1H4D 0.72 5.46 0.44 2.52e-7 Intelligence (multi-trait analysis); TGCT cis rs10465746 0.780 rs7550413 chr1:84423891 T/A cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg00024416 chr22:24240387 NA -0.25 -4.91 -0.4 2.86e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11190604 0.945 rs11190553 chr10:102207959 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7511006 0.893 rs760743 chr22:50647375 C/T cg16473166 chr22:50639996 SELO 0.66 6.49 0.5 1.88e-9 Obesity-related traits; TGCT cis rs6754311 0.593 rs10928542 chr2:136410299 G/A cg07169764 chr2:136633963 MCM6 0.67 5.91 0.47 3.16e-8 Mosquito bite size; TGCT cis rs910316 0.783 rs11850751 chr14:75590113 A/T cg11812906 chr14:75593930 NEK9 0.73 7.23 0.54 4.36e-11 Height; TGCT cis rs1008375 0.966 rs3796812 chr4:17582051 G/A cg10189774 chr4:17578691 LAP3 0.58 5.15 0.42 9.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7845219 0.544 rs7016078 chr8:95922615 G/A cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs5750830 0.649 rs7949 chr22:39827553 G/A cg11247378 chr22:39784982 NA -0.73 -9.83 -0.66 3.22e-17 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.961 rs211710 chr1:76109038 G/A cg03433033 chr1:76189801 ACADM -0.84 -10.0 -0.67 1.28e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2204008 0.619 rs8189576 chr12:38307275 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs3087591 0.960 rs4263003 chr17:29438508 G/T cg24425628 chr17:29625626 OMG;NF1 0.49 7.28 0.55 3.29e-11 Hip circumference; TGCT cis rs9325144 0.647 rs12229104 chr12:39110811 T/A cg10518543 chr12:38710700 ALG10B -0.48 -4.5 -0.37 1.52e-5 Morning vs. evening chronotype; TGCT trans rs4919669 0.668 rs3824756 chr10:104359350 T/C cg24066601 chr6:26271455 HIST1H3G 0.66 6.81 0.52 3.7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs67311347 1.000 rs7628247 chr3:40512682 G/T cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs4713118 0.621 rs9368548 chr6:28034737 A/G cg12963246 chr6:28129442 ZNF389 0.47 4.74 0.39 5.69e-6 Parkinson's disease; TGCT cis rs826838 1.000 rs826838 chr12:39106731 C/T cg13010199 chr12:38710504 ALG10B -0.55 -4.52 -0.38 1.45e-5 Heart rate; TGCT cis rs4819052 1.000 rs4819052 chr21:46699777 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 5.52 0.44 1.87e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs921968 0.541 rs2710246 chr2:219533894 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.3 0.49 4.77e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs7267979 1.000 rs4815412 chr20:25350325 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9814567 0.806 rs6806810 chr3:134323522 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.77 -7.21 -0.54 4.87e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs11722228 0.549 rs3796818 chr4:10097976 C/T cg26043149 chr18:55253948 FECH 1.16 11.2 0.71 1.55e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs6570726 0.791 rs440477 chr6:145854188 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7940866 0.903 rs10791112 chr11:130870215 A/C cg12179176 chr11:130786555 SNX19 -0.55 -5.59 -0.45 1.41e-7 Schizophrenia; TGCT cis rs4713118 0.523 rs2179096 chr6:27665920 C/T cg10876282 chr6:28092338 ZSCAN16 0.48 4.86 0.4 3.48e-6 Parkinson's disease; TGCT cis rs13242816 1.000 rs34082946 chr7:116154313 G/A cg02799643 chr7:116139180 CAV2 -0.44 -5.54 -0.45 1.74e-7 P wave duration; TGCT cis rs12188164 0.686 rs11741946 chr5:421403 G/A cg22025206 chr5:502436 SLC9A3 -0.26 -4.53 -0.38 1.36e-5 Cystic fibrosis severity; TGCT cis rs11190604 0.767 rs4559620 chr10:102199935 C/T cg16342193 chr10:102329863 NA -0.42 -5.26 -0.43 6.02e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs909002 0.925 rs7524405 chr1:32108579 A/C cg11573219 chr1:32083031 HCRTR1 0.45 5.86 0.47 3.94e-8 Intelligence (multi-trait analysis); TGCT cis rs864745 0.967 rs860262 chr7:28194397 C/A cg23620719 chr7:28220237 JAZF1 -0.48 -4.54 -0.38 1.33e-5 Crohn's disease;Type 2 diabetes; TGCT trans rs10953454 1.000 rs12535201 chr7:104501521 C/T cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs9660180 0.836 rs12038134 chr1:1703865 T/A cg03396347 chr1:1875803 NA -0.36 -6.58 -0.51 1.18e-9 Body mass index; TGCT cis rs7618915 0.501 rs13060048 chr3:52598608 G/A cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs1784581 0.588 rs1789988 chr6:162408472 C/T cg17173639 chr6:162384350 PARK2 -0.42 -7.14 -0.54 6.78e-11 Itch intensity from mosquito bite; TGCT cis rs2710642 0.821 rs56373728 chr2:63095792 G/A cg17519650 chr2:63277830 OTX1 0.59 5.33 0.43 4.49e-7 LDL cholesterol levels;LDL cholesterol; TGCT cis rs4242434 0.927 rs3735901 chr8:22462374 T/C cg03733263 chr8:22462867 KIAA1967 1.15 20.01 0.87 1.19e-40 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs17376456 0.778 rs10476604 chr5:93461838 C/T cg21475434 chr5:93447410 FAM172A 0.62 5.78 0.46 5.64e-8 Diabetic retinopathy; TGCT trans rs2624839 0.704 rs2624838 chr3:50205642 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.73 6.73 0.52 5.49e-10 Intelligence (multi-trait analysis); TGCT cis rs826838 1.000 rs11169031 chr12:39056738 T/C cg13010199 chr12:38710504 ALG10B 0.77 6.3 0.49 4.68e-9 Heart rate; TGCT trans rs9383153 1.000 rs2073518 chr6:16332730 T/C cg22767166 chr8:49833685 SNAI2 0.87 6.64 0.51 9e-10 Gambling; TGCT cis rs3935685 1.000 rs10851896 chr15:78026325 C/T cg25212270 chr15:78015279 NA 0.28 5.29 0.43 5.34e-7 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.935 rs1680072 chr4:1281695 T/G cg03303774 chr4:1407052 NA -0.32 -4.92 -0.4 2.7e-6 Obesity-related traits; TGCT cis rs57677839 1 rs57677839 chr11:17028189 G/A cg15084286 chr11:17036142 PLEKHA7 0.91 12.38 0.74 2.02e-23 Coronary artery disease; TGCT cis rs3892630 0.588 rs7248798 chr19:33303684 G/T cg22980127 chr19:33182716 NUDT19 0.74 5.98 0.47 2.17e-8 Red blood cell traits; TGCT trans rs1814175 0.791 rs10219223 chr11:49791468 A/T cg15704280 chr7:45808275 SEPT13 -0.7 -8.08 -0.59 4.89e-13 Height; TGCT cis rs713587 0.776 rs3731623 chr2:25163783 T/C cg01884057 chr2:25150051 NA 0.39 7.97 0.58 8.81e-13 Body mass index in non-asthmatics; TGCT cis rs4665809 0.941 rs1470096 chr2:26311482 T/C cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs151997 0.925 rs27579 chr5:50165147 G/A cg06027927 chr5:50259733 NA 0.47 4.74 0.39 5.75e-6 Callous-unemotional behaviour; TGCT cis rs35883536 0.647 rs59667512 chr1:101046712 C/T cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs9814567 1.000 rs12490835 chr3:134223730 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs11167764 1.000 rs11167764 chr5:141479065 A/C cg02659431 chr5:141694439 SPRY4 -0.22 -4.67 -0.39 7.84e-6 Crohn's disease; TGCT cis rs778371 0.874 rs1083522 chr2:233745521 C/T cg25237894 chr2:233734115 C2orf82 -0.24 -4.47 -0.37 1.71e-5 Schizophrenia; TGCT cis rs9807989 0.811 rs4485584 chr2:102970750 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs2108225 0.837 rs6466186 chr7:107446966 G/C cg20438043 chr7:107601757 LAMB1 -0.24 -4.49 -0.37 1.63e-5 Ulcerative colitis; TGCT cis rs190945449 1 rs190945449 chr6:26828359 C/T cg16898833 chr6:26189333 HIST1H4D 1.1 5.46 0.44 2.47e-7 Urinary tract infection frequency; TGCT cis rs2404602 1.000 rs11072603 chr15:76881138 G/T cg26408565 chr15:76604113 ETFA -0.38 -4.82 -0.4 4.03e-6 Blood metabolite levels; TGCT cis rs2456568 0.709 rs1354765 chr11:93637776 G/T cg16099599 chr11:93583650 C11orf90 0.39 4.75 0.39 5.63e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9430161 0.645 rs6675082 chr1:11033797 T/C cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg24675658 chr1:53192096 ZYG11B -0.74 -9.22 -0.64 9.770000000000001e-16 Monocyte count; TGCT cis rs478304 0.651 rs4014195 chr11:65506822 C/G cg27068330 chr11:65405492 SIPA1 0.96 9.88 0.66 2.5e-17 Acne (severe); TGCT cis rs910316 1.000 rs175512 chr14:75523382 T/C cg08847533 chr14:75593920 NEK9 -0.95 -10.36 -0.68 1.73e-18 Height; TGCT cis rs7772486 0.875 rs9390377 chr6:146386932 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 0.568 rs7203907 chr16:89833774 C/G cg03388025 chr16:89894329 SPIRE2 0.48 8.35 0.6 1.15e-13 Vitiligo; TGCT cis rs669446 0.562 rs11210907 chr1:44191759 C/T cg12908607 chr1:44402522 ARTN -0.59 -6.47 -0.5 2.02e-9 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs9733 0.596 rs72702570 chr1:150688196 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs9467773 0.967 rs6456732 chr6:26514445 T/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.529 rs6060174 chr20:30183538 G/A cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs769267 1.000 rs8103197 chr19:19443466 C/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs11249608 0.548 rs2132672 chr5:178457742 A/C cg01312482 chr5:178451176 ZNF879 -0.49 -4.82 -0.4 4.11e-6 Pubertal anthropometrics; TGCT cis rs6988636 0.892 rs58116120 chr8:124191776 T/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs2067615 0.524 rs10778503 chr12:107090616 C/T cg15890332 chr12:107067104 RFX4 0.29 5.82 0.46 4.61e-8 Heart rate; TGCT cis rs9325144 0.647 rs1386018 chr12:39104360 C/T cg26384229 chr12:38710491 ALG10B -0.57 -5.29 -0.43 5.23e-7 Morning vs. evening chronotype; TGCT cis rs9486719 1.000 rs13210597 chr6:96969694 C/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.81 -0.62 9.21e-15 Migraine;Coronary artery disease; TGCT cis rs7914558 0.901 rs1926034 chr10:104829102 G/A cg04362960 chr10:104952993 NT5C2 0.55 4.73 0.39 6.11e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg16145915 chr7:1198662 ZFAND2A -0.55 -7.04 -0.53 1.14e-10 Longevity;Endometriosis; TGCT cis rs4803455 0.586 rs4803457 chr19:41861359 T/C cg09537434 chr19:41945824 ATP5SL -0.53 -5.25 -0.43 6.35e-7 Migraine;Coronary artery disease; TGCT cis rs4953076 0.573 rs7602070 chr2:44388614 G/A cg04920474 chr2:44395004 PPM1B 0.61 6.07 0.48 1.45e-8 Height; TGCT cis rs7017914 0.967 rs12679261 chr8:71844649 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.52 -4.81 -0.4 4.3e-6 Bone mineral density; TGCT cis rs7089973 0.604 rs11196942 chr10:116596872 G/A cg03647239 chr10:116582469 FAM160B1 0.58 5.66 0.45 9.75e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs6430585 0.702 rs746857 chr2:136554890 G/A cg19039313 chr2:136634366 MCM6 0.24 4.64 0.38 8.84e-6 Corneal structure; TGCT cis rs17767294 0.708 rs72848752 chr6:27878268 A/C cg08851530 chr6:28072375 NA 1.53 7.17 0.54 6.02e-11 Parkinson's disease; TGCT cis rs4862750 0.914 rs6553026 chr4:187875648 C/T cg10295955 chr4:187884368 NA -0.97 -14.67 -0.8 7e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.654 rs6928007 chr6:146074941 G/A cg05347473 chr6:146136440 FBXO30 -0.49 -4.52 -0.38 1.42e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2235642 0.787 rs2235646 chr16:1601287 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.34 -6.14 -0.48 1.01e-8 Coronary artery disease; TGCT cis rs9467711 0.720 rs75782365 chr6:26408551 T/G cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.572 rs139569 chr22:42211141 A/G cg17554472 chr22:41940697 POLR3H -0.44 -4.72 -0.39 6.23e-6 Vitiligo; TGCT cis rs17030434 0.954 rs79908936 chr4:154749305 C/T cg14289246 chr4:154710475 SFRP2 -0.9 -6.97 -0.53 1.65e-10 Electrocardiographic conduction measures; TGCT cis rs9611565 0.649 rs139540 chr22:42178040 C/T cg06481639 chr22:41940642 POLR3H -0.58 -4.83 -0.4 4e-6 Vitiligo; TGCT cis rs6933660 0.745 rs3800272 chr6:151744283 A/G cg17179660 chr6:151773299 C6orf211;RMND1 0.51 4.77 0.39 5e-6 Menarche (age at onset); TGCT cis rs7192750 0.562 rs9888748 chr16:71987851 G/A cg06353428 chr16:71660113 MARVELD3 0.74 6.6 0.51 1.09e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg13699009 chr12:122356056 WDR66 -0.34 -8.18 -0.59 2.8e-13 Mean corpuscular volume; TGCT cis rs11644362 1.000 rs35972357 chr16:12987664 C/T cg06890432 chr16:12997467 SHISA9 -0.6 -6.49 -0.5 1.88e-9 Positive affect;Subjective well-being; TGCT cis rs3796619 1.000 rs2290409 chr4:1067249 C/T cg27284194 chr4:1044797 NA -0.46 -4.48 -0.37 1.66e-5 Recombination rate (males); TGCT cis rs12549902 1.000 rs12549902 chr8:41509259 C/T cg00088007 chr8:41504566 NKX6-3 0.34 5.38 0.43 3.59e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs3806843 0.576 rs246020 chr5:140334771 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs2228479 0.867 rs11645970 chr16:89958118 G/A cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs6964587 0.900 rs6465352 chr7:91775117 A/G cg17063962 chr7:91808500 NA 0.93 10.08 0.67 8.03e-18 Breast cancer; TGCT cis rs3087591 0.666 rs2953016 chr17:29494693 C/G cg24425628 chr17:29625626 OMG;NF1 0.42 5.56 0.45 1.55e-7 Hip circumference; TGCT cis rs2204008 0.837 rs4432085 chr12:38181146 C/T cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs881375 0.933 rs4837804 chr9:123705304 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.72 0.39 6.28e-6 Rheumatoid arthritis; TGCT cis rs12541335 0.692 rs2290274 chr8:22214374 C/T cg00420450 chr8:22132641 PIWIL2 0.24 4.53 0.38 1.36e-5 Hypertriglyceridemia; TGCT cis rs3820928 0.904 rs2396431 chr2:227765488 G/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.68 -0.39 7.37e-6 Pulmonary function; TGCT cis rs40363 0.645 rs250627 chr16:3527050 G/A cg21433313 chr16:3507492 NAT15 0.36 4.61 0.38 9.85e-6 Tuberculosis; TGCT cis rs13256369 0.802 rs1060106 chr8:8561452 A/G cg17143192 chr8:8559678 CLDN23 0.54 5.03 0.41 1.64e-6 Obesity-related traits; TGCT cis rs68170813 0.559 rs61406169 chr7:106903421 A/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs9486719 1.000 rs4077932 chr6:96905144 C/T cg06623918 chr6:96969491 KIAA0776 -0.98 -8.77 -0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs12220238 1.000 rs7083534 chr10:75955672 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.48 0.56 1.16e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3813359 0.614 rs17059066 chr6:130769858 C/T cg25049486 chr6:130544510 SAMD3 0.39 4.75 0.39 5.61e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs3749237 0.595 rs11130199 chr3:49538799 T/C cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs2197308 0.610 rs10880837 chr12:37864924 C/T cg26384229 chr12:38710491 ALG10B 0.89 7.93 0.58 1.09e-12 Morning vs. evening chronotype; TGCT cis rs6598955 0.671 rs11247909 chr1:26640135 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs1949733 1.000 rs2631745 chr4:8490530 T/C cg13073564 chr4:8508604 NA 0.5 5.55 0.45 1.63e-7 Response to antineoplastic agents; TGCT cis rs9583531 0.600 rs6492306 chr13:111361693 G/A cg24331049 chr13:111365604 ING1 0.74 7.22 0.54 4.61e-11 Coronary artery disease; TGCT cis rs1801251 0.778 rs2592116 chr2:233735709 G/A cg08000102 chr2:233561755 GIGYF2 -0.44 -4.45 -0.37 1.87e-5 Coronary artery disease; TGCT cis rs6840360 0.554 rs10222838 chr4:152690099 T/C cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.62e-8 Intelligence (multi-trait analysis); TGCT cis rs9911578 0.967 rs9907940 chr17:56663842 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs12477438 1.000 rs995617 chr2:99857904 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.96 8.25 0.6 1.96e-13 Chronic sinus infection; TGCT cis rs9914544 0.545 rs12451200 chr17:18778493 A/G cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.06e-6 Educational attainment (years of education); TGCT cis rs5769707 0.681 rs6009803 chr22:50051007 A/G cg05373962 chr22:49881684 NA -0.32 -5.52 -0.44 1.87e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9560113 1.000 rs4773384 chr13:112177987 A/G cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs1670533 0.932 rs3796620 chr4:1095079 A/G cg27284194 chr4:1044797 NA -0.69 -6.07 -0.48 1.45e-8 Recombination rate (females); TGCT cis rs4076764 1.000 rs4469696 chr1:163424565 C/T cg24596788 chr1:163392923 NA -0.16 -4.56 -0.38 1.22e-5 Motion sickness; TGCT cis rs7666738 0.830 rs2098934 chr4:98992403 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.609 rs28833816 chr4:98868866 T/C cg05340658 chr4:99064831 C4orf37 0.56 5.96 0.47 2.4e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9549260 0.755 rs1413482 chr13:41218451 C/T cg21288729 chr13:41239152 FOXO1 1.01 10.64 0.69 3.45e-19 Red blood cell count; TGCT cis rs11971779 0.715 rs11772771 chr7:139058803 T/C cg07862535 chr7:139043722 LUC7L2 0.7 5.49 0.44 2.13e-7 Diisocyanate-induced asthma; TGCT cis rs986417 1.000 rs2224410 chr14:60970531 T/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs1153858 0.943 rs7402632 chr15:45701913 A/T cg26924012 chr15:45694286 SPATA5L1 1.1 15.34 0.81 2.01e-30 Homoarginine levels; TGCT cis rs17331151 0.512 rs9637477 chr3:52891426 G/C cg12962167 chr3:53033115 SFMBT1 -0.42 -4.83 -0.4 3.88e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1903068 0.853 rs9312657 chr4:56003502 G/A cg09978860 chr4:56023921 NA 0.56 6.34 0.49 3.88e-9 Endometriosis; TGCT cis rs9393777 0.557 rs36034627 chr6:27237363 G/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.55 -4.59 -0.38 1.09e-5 Intelligence (multi-trait analysis); TGCT cis rs12477438 1.000 rs11897712 chr2:99735697 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.74 -5.46 -0.44 2.5e-7 Chronic sinus infection; TGCT cis rs11098499 0.954 rs35063680 chr4:120387102 T/C cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs1799949 1.000 rs2292595 chr17:41290674 G/C cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs739401 0.611 rs450817 chr11:3056712 A/G cg05729581 chr11:3078854 CARS -0.55 -5.19 -0.42 8.19e-7 Longevity; TGCT cis rs6815814 0.731 rs11735251 chr4:38773057 T/A cg02016764 chr4:38805732 TLR1 -0.27 -4.54 -0.38 1.32e-5 Breast cancer; TGCT cis rs6463523 0.933 rs6974151 chr7:758269 T/C cg11064039 chr7:766100 PRKAR1B;HEATR2 0.93 11.59 0.72 1.68e-21 Subjective well-being; TGCT cis rs10197940 0.578 rs1061305 chr2:152346979 T/C cg19508488 chr2:152266495 RIF1 0.59 4.98 0.41 2.11e-6 Lung cancer; TGCT trans rs10506458 0.915 rs998505 chr12:63400018 C/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs10464366 0.544 rs4355688 chr7:39158402 C/T cg15212455 chr7:39170539 POU6F2 0.3 6.63 0.51 9.08e-10 IgG glycosylation; TGCT cis rs473651 0.935 rs541013 chr2:239336492 G/A cg21699342 chr2:239360505 ASB1 0.18 4.89 0.4 3.05e-6 Multiple system atrophy; TGCT cis rs3772130 0.540 rs7649436 chr3:121562304 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.6 5.56 0.45 1.55e-7 Cognitive performance; TGCT cis rs6969780 0.673 rs2301721 chr7:27196113 C/T cg17457637 chr7:27170717 HOXA4 -0.44 -4.81 -0.4 4.29e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs11250097 0.507 rs2409779 chr8:11311340 A/T cg01383082 chr8:11323474 FAM167A 0.27 4.48 0.37 1.66e-5 Neuroticism; TGCT cis rs981844 0.775 rs62323979 chr4:154752935 T/C cg14289246 chr4:154710475 SFRP2 1.0 8.63 0.61 2.53e-14 Response to statins (LDL cholesterol change); TGCT cis rs9549367 0.789 rs71446682 chr13:113894908 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs295140 1.000 rs7599609 chr2:201177653 G/A cg04283868 chr2:201171347 SPATS2L 0.65 6.66 0.51 7.99e-10 QT interval; TGCT cis rs9906944 0.545 rs1994969 chr17:47080431 G/T cg20966754 chr17:47091339 IGF2BP1 -0.41 -4.49 -0.37 1.63e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs28595532 0.920 rs115085630 chr4:119741765 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9868809 0.505 rs28793701 chr3:48762683 C/G cg03547606 chr3:48723644 NCKIPSD 0.46 4.55 0.38 1.28e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs908922 0.676 rs493133 chr1:152493875 G/C cg20991723 chr1:152506922 NA 0.46 6.26 0.49 5.7e-9 Hair morphology; TGCT cis rs4595586 0.545 rs1356265 chr12:39403696 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs751728 0.638 rs4607416 chr6:33784998 G/C cg13859433 chr6:33739653 LEMD2 -0.37 -6.45 -0.5 2.21e-9 Crohn's disease; TGCT cis rs950169 0.840 rs62019457 chr15:85102142 T/C cg11189052 chr15:85197271 WDR73 0.81 6.71 0.52 6.33e-10 Schizophrenia; TGCT cis rs10736390 1.000 rs10736390 chr1:55103945 A/G cg01517571 chr1:55089959 ACOT11;FAM151A -0.42 -8.39 -0.6 9.18e-14 Survival in pancreatic cancer; TGCT cis rs12477438 0.798 rs6761570 chr2:99577276 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs921968 0.541 rs58650092 chr2:219304851 C/A cg02176678 chr2:219576539 TTLL4 -0.47 -6.59 -0.51 1.15e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs7772486 0.790 rs2265918 chr6:146219164 A/G cg23711669 chr6:146136114 FBXO30 0.89 10.16 0.67 5.28e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.875 rs2777483 chr6:146329235 A/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.48 -0.37 1.67e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9457247 0.967 rs377753 chr6:167389496 A/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs1577917 1.000 rs13194429 chr6:86646705 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs3845702 0.736 rs12693214 chr2:180825685 G/A cg01881094 chr2:180872142 CWC22 -1.03 -6.51 -0.5 1.72e-9 Schizophrenia; TGCT cis rs7772486 0.790 rs2254283 chr6:146204289 T/C cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 0.924 rs7544117 chr1:76158246 A/G cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9788682 0.947 rs12439240 chr15:78829091 T/C cg06917634 chr15:78832804 PSMA4 -0.71 -4.93 -0.4 2.63e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9911578 0.933 rs74370218 chr17:57095212 C/T cg12560992 chr17:57184187 TRIM37 -0.78 -9.58 -0.65 1.35e-16 Intelligence (multi-trait analysis); TGCT cis rs986417 0.748 rs10142927 chr14:61041956 A/G cg18240143 chr14:60952599 C14orf39 0.82 4.51 0.38 1.46e-5 Gut microbiota (bacterial taxa); TGCT cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs4478858 0.684 rs1546375 chr1:31765968 C/T cg00250761 chr1:31883323 NA -0.25 -4.48 -0.37 1.64e-5 Alcohol dependence; TGCT cis rs2760061 0.819 rs708120 chr1:228207651 G/C cg02753203 chr1:228287806 NA 0.3 5.71 0.46 8.06e-8 Diastolic blood pressure; TGCT cis rs7267979 0.789 rs6076347 chr20:25398790 C/T cg21995068 chr20:25989032 LOC100134868 0.42 5.07 0.41 1.43e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs612683 0.536 rs1335753 chr1:101027157 G/T cg06223162 chr1:101003688 GPR88 0.34 5.93 0.47 2.86e-8 Breast cancer; TGCT cis rs2439831 0.681 rs2242067 chr15:43699303 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.04 6.72 0.52 5.82e-10 Lung cancer in ever smokers; TGCT cis rs9926296 0.585 rs4785595 chr16:89835521 C/T cg04287289 chr16:89883240 FANCA -0.83 -9.77 -0.66 4.58e-17 Vitiligo; TGCT cis rs478304 0.654 rs1074156 chr11:65458169 G/T cg17480646 chr11:65405466 SIPA1 -0.62 -7.6 -0.56 6.27e-12 Acne (severe); TGCT cis rs7666738 0.830 rs4441757 chr4:98927059 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10791323 0.604 rs2723615 chr11:133704567 C/T cg03690763 chr11:133734501 NA -0.35 -5.33 -0.43 4.52e-7 Childhood ear infection; TGCT cis rs6933660 0.800 rs13201167 chr6:151773504 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.72 7.43 0.55 1.57e-11 Menarche (age at onset); TGCT cis rs2239547 0.522 rs6445550 chr3:52983434 G/A cg11645453 chr3:52864694 ITIH4 0.3 4.88 0.4 3.21e-6 Schizophrenia; TGCT cis rs62209 0.752 rs11256941 chr10:11017020 G/T cg26901096 chr10:10994189 LOC254312 0.36 5.96 0.47 2.48e-8 Alzheimer's disease (late onset); TGCT cis rs9790314 0.631 rs2061804 chr3:161102474 C/A cg03342759 chr3:160939853 NMD3 -0.46 -4.93 -0.4 2.57e-6 Morning vs. evening chronotype; TGCT cis rs1538970 0.962 rs4660849 chr1:45819872 A/G cg05343316 chr1:45956843 TESK2 -0.63 -5.03 -0.41 1.71e-6 Platelet count; TGCT cis rs6540559 0.611 rs17015226 chr1:209970096 C/G cg22029157 chr1:209979665 IRF6 0.79 5.93 0.47 2.81e-8 Cleft lip with or without cleft palate; TGCT cis rs826838 0.967 rs6580726 chr12:39108623 T/C cg26384229 chr12:38710491 ALG10B -0.87 -8.1 -0.59 4.43e-13 Heart rate; TGCT cis rs9814567 1.000 rs4572812 chr3:134291177 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs651907 0.557 rs35850993 chr3:101437433 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.9 10.87 0.7 9.43e-20 Colorectal cancer; TGCT cis rs4499344 0.556 rs259219 chr19:33138067 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.79 7.83 0.58 1.89e-12 Mean platelet volume; TGCT cis rs1691799 0.867 rs1168311 chr12:66725912 A/C cg16791601 chr12:66731901 HELB 0.28 6.18 0.49 8.47e-9 White blood cell count (basophil); TGCT cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs11642862 1.000 rs11641321 chr16:30880319 G/A cg02466173 chr16:30829666 NA -0.38 -4.45 -0.37 1.91e-5 Tonsillectomy; TGCT cis rs1532993 0.518 rs9994066 chr4:98591202 T/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.91 -0.4 2.81e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs7119 0.604 rs2667783 chr15:77862529 G/A cg27398640 chr15:77910606 LINGO1 0.27 4.78 0.39 4.84e-6 Type 2 diabetes; TGCT cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg03264133 chr6:25882463 NA -0.51 -5.28 -0.43 5.69e-7 Height; TGCT cis rs12497850 0.931 rs6442130 chr3:48778027 A/G cg05785598 chr3:49045655 WDR6 0.35 4.64 0.38 8.79e-6 Parkinson's disease; TGCT cis rs17253792 0.732 rs28380739 chr14:56088402 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg11211951 chr8:145729740 GPT -0.21 -4.89 -0.4 3e-6 Age at first birth; TGCT trans rs3780486 0.846 rs6476399 chr9:33123013 A/G cg04842962 chr6:43655489 MRPS18A 1.23 15.36 0.81 1.81e-30 IgG glycosylation; TGCT cis rs7666738 1.000 rs880473 chr4:98922596 C/T cg18180107 chr4:99064573 C4orf37 0.56 4.45 0.37 1.9e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.26 0.43 6.03e-7 Menopause (age at onset); TGCT cis rs5769707 0.521 rs5770633 chr22:50062427 G/A cg05373962 chr22:49881684 NA -0.32 -5.47 -0.44 2.43e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1887596 0.624 rs9553864 chr13:27152649 C/T cg01312412 chr13:27282625 NA 0.27 4.86 0.4 3.51e-6 Facial morphology (factor 3, length of philtrum); TGCT trans rs62103177 0.810 rs62103194 chr18:77629482 G/A cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs7249142 0.506 rs8101388 chr19:19293938 A/C cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.54 5.41 0.44 3.14e-7 IgG glycosylation; TGCT cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg24549020 chr5:56110836 MAP3K1 0.69 5.91 0.47 3.09e-8 Initial pursuit acceleration; TGCT cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg20607798 chr8:58055168 NA 0.45 4.59 0.38 1.06e-5 Developmental language disorder (linguistic errors); TGCT cis rs9952991 0.941 rs2542150 chr18:12779763 G/C cg24737193 chr18:12778029 NA 0.54 6.03 0.48 1.76e-8 Inflammatory skin disease; TGCT cis rs9394841 0.810 rs1410492 chr6:41907855 G/C cg08135965 chr6:41755394 TOMM6 0.56 5.35 0.43 4.05e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT trans rs1814175 0.645 rs28839231 chr11:50044292 G/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs79349575 0.749 rs46521 chr17:46988529 A/G cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg02187348 chr16:89574699 SPG7 0.64 6.82 0.52 3.55e-10 Multiple myeloma (IgH translocation); TGCT cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg17971929 chr21:40555470 PSMG1 0.93 8.45 0.6 6.46e-14 Cognitive function; TGCT cis rs4642101 0.669 rs1467026 chr3:12830775 G/A cg05775895 chr3:12838266 CAND2 0.67 7.21 0.54 4.91e-11 QRS complex (12-leadsum); TGCT cis rs7246657 0.722 rs2927742 chr19:38133618 T/C cg03611452 chr19:38183253 ZNF781 -0.58 -4.67 -0.39 7.7e-6 Coronary artery calcification; TGCT cis rs801193 1.000 rs2659889 chr7:66217112 A/G cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.84e-7 Aortic root size; TGCT cis rs7843479 0.601 rs11781959 chr8:21841863 C/G cg17168535 chr8:21777572 XPO7 0.8 8.02 0.58 6.73e-13 Mean corpuscular volume; TGCT cis rs11105298 0.891 rs10858890 chr12:89907166 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.66 -4.8 -0.4 4.44e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg10150615 chr22:24372951 LOC391322 -0.81 -8.99 -0.63 3.44e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs704 0.628 rs241775 chr17:26644668 C/T cg10342447 chr17:26645325 TMEM97 0.59 5.63 0.45 1.15e-7 Osteoprotegerin levels; TGCT cis rs742614 0.935 rs6057929 chr20:32477633 A/G cg03217337 chr20:32447030 NA -0.22 -4.63 -0.38 9.03e-6 Stearic acid (18:0) levels; TGCT cis rs7829975 0.560 rs56094035 chr8:8551622 G/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.31 -0.43 4.81e-7 Mood instability; TGCT cis rs1629083 0.935 rs1540191 chr11:118090432 G/A cg16594165 chr11:118135105 MPZL2 -0.33 -4.7 -0.39 6.73e-6 Lung cancer; TGCT cis rs8072100 0.777 rs9914653 chr17:45537395 T/C cg08085267 chr17:45401833 C17orf57 -0.46 -5.07 -0.41 1.39e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9467773 1.000 rs9393729 chr6:26514166 C/T cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs2338224 1.000 rs10942300 chr5:71745412 C/T cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs497273 0.534 rs608394 chr12:121194053 C/T cg02419362 chr12:121203948 SPPL3 0.19 4.52 0.38 1.43e-5 Systemic lupus erythematosus; TGCT cis rs1372520 0.627 rs2583964 chr4:90727218 A/G cg15133208 chr4:90757351 SNCA -0.52 -6.07 -0.48 1.44e-8 Neuroticism; TGCT cis rs10992471 0.756 rs2516568 chr9:95187380 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.31 -0.49 4.46e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2639990 1.000 rs632157 chr18:72911548 G/A cg03972071 chr18:72917163 ZADH2 0.8 5.4 0.44 3.3e-7 Vascular endothelial growth factor levels; TGCT cis rs2153535 0.580 rs7767756 chr6:8453428 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs7666738 0.830 rs11931166 chr4:99054187 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12579753 0.879 rs11115010 chr12:82165895 G/T cg07988820 chr12:82153109 PPFIA2 -0.69 -7.77 -0.57 2.56e-12 Resting heart rate; TGCT cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.69 0.39 7.09e-6 Vitiligo; TGCT trans rs1814175 0.817 rs28544182 chr11:50049577 G/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs7659604 0.628 rs6838153 chr4:122720999 A/G cg20573242 chr4:122745356 CCNA2 0.64 5.71 0.46 7.81e-8 Type 2 diabetes; TGCT cis rs709400 0.628 rs12889639 chr14:103860206 G/A cg12935359 chr14:103987150 CKB 0.34 5.2 0.42 7.86e-7 Body mass index; TGCT cis rs10927875 0.726 rs1763603 chr1:16339809 T/C cg22431228 chr1:16359049 CLCNKA -0.25 -4.76 -0.39 5.23e-6 Dilated cardiomyopathy; TGCT cis rs7666738 0.716 rs2865982 chr4:99031661 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7119 0.717 rs8032405 chr15:77825344 A/G cg27398640 chr15:77910606 LINGO1 -0.26 -4.68 -0.39 7.4e-6 Type 2 diabetes; TGCT cis rs2075371 1.000 rs2058976 chr7:133981379 G/T cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT trans rs9354352 0.967 rs6455062 chr6:66694131 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.72 7.89 0.58 1.33e-12 Initial pursuit acceleration in psychotic disorders; TGCT trans rs4332037 1.000 rs4332037 chr7:1950809 C/T cg25206134 chr2:45395956 NA 1.12 9.49 0.65 2.13e-16 Bipolar disorder; TGCT cis rs763121 0.853 rs6001184 chr22:39052116 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs10479542 0.701 rs10479541 chr5:178981003 G/C cg14851468 chr5:179071604 C5orf60 0.23 4.66 0.39 8.05e-6 Lung cancer; TGCT cis rs854765 0.583 rs9890341 chr17:17823175 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.69 0.57 3.91e-12 Total body bone mineral density; TGCT cis rs7940866 0.834 rs2324315 chr11:130839772 C/G cg12179176 chr11:130786555 SNX19 0.62 5.93 0.47 2.75e-8 Schizophrenia; TGCT cis rs449303 1 rs449303 chr14:60605788 A/G cg00846580 chr14:60632234 DHRS7 0.97 5.29 0.43 5.38e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs61990749 0.597 rs12887282 chr14:78200585 C/A cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs6714710 0.603 rs13020776 chr2:98402753 T/A cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2072499 1.000 rs2072499 chr1:156169610 A/G cg24450063 chr1:156163899 SLC25A44 1.17 17.33 0.84 6.21e-35 Testicular germ cell tumor; TGCT cis rs3812831 0.630 rs9562129 chr13:114917152 A/G cg08824895 chr13:115047677 UPF3A 0.49 4.65 0.39 8.5e-6 Schizophrenia; TGCT cis rs1153858 1.000 rs2467858 chr15:45711492 A/G cg14582100 chr15:45693742 SPATA5L1 0.47 5.62 0.45 1.22e-7 Homoarginine levels; TGCT cis rs2439831 0.850 rs12442129 chr15:44055856 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs6570726 0.516 rs10484700 chr6:145728933 C/T cg23711669 chr6:146136114 FBXO30 0.6 5.48 0.44 2.32e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg03264133 chr6:25882463 NA -0.52 -5.38 -0.44 3.53e-7 Blood metabolite levels; TGCT cis rs7103648 0.966 rs874896 chr11:47418953 C/G cg20307385 chr11:47447363 PSMC3 1.02 12.18 0.74 6.15e-23 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs11931598 0.514 rs10937779 chr4:7039326 G/A cg26116260 chr4:7069785 GRPEL1 0.62 5.97 0.47 2.27e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs6570726 0.791 rs6902410 chr6:145905261 G/A cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs8179 0.645 rs10953072 chr7:92256339 A/C cg15732164 chr7:92237376 CDK6 -0.27 -4.64 -0.38 8.79e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs1008375 1.000 rs13106338 chr4:17676871 G/T cg10189774 chr4:17578691 LAP3 -0.59 -5.24 -0.43 6.8e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7919533 0.584 rs2894169 chr10:73524622 A/G cg00101602 chr10:73857843 ASCC1 0.29 4.56 0.38 1.22e-5 Monocyte count; TGCT cis rs3087591 0.553 rs2854334 chr17:29715500 A/G cg24425628 chr17:29625626 OMG;NF1 0.4 5.86 0.47 3.98e-8 Hip circumference; TGCT cis rs13188771 0.690 rs12519215 chr5:100898218 A/G cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs3617 0.532 rs9836499 chr3:52904524 G/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.47 -4.46 -0.37 1.83e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs933688 0.938 rs7708782 chr5:90718517 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.17 0.59 3.05e-13 Smoking behavior; TGCT cis rs10509586 0.826 rs77211714 chr10:91898746 G/A cg25278353 chr10:91717815 NA 0.49 4.67 0.39 7.77e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs17376456 0.825 rs13164315 chr5:93147421 A/G cg25358565 chr5:93447407 FAM172A 0.9 7.6 0.56 6.43e-12 Diabetic retinopathy; TGCT cis rs35306767 0.855 rs56222464 chr10:867535 C/G cg20503657 chr10:835505 NA 0.77 11.28 0.71 9.73e-21 Eosinophil percentage of granulocytes; TGCT cis rs904251 0.504 rs12202664 chr6:37481198 A/G cg01843034 chr6:37503916 NA -0.55 -7.42 -0.55 1.63e-11 Cognitive performance; TGCT cis rs9372498 0.536 rs62422221 chr6:118925581 T/C cg21191810 chr6:118973309 C6orf204 -0.38 -4.98 -0.41 2.04e-6 Diastolic blood pressure; TGCT cis rs9611565 0.512 rs4820444 chr22:42202606 A/G cg06481639 chr22:41940642 POLR3H 0.69 6.02 0.48 1.83e-8 Vitiligo; TGCT cis rs1461503 0.966 rs11218907 chr11:122841562 A/G cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg10802521 chr3:52805072 NEK4 -0.64 -7.66 -0.57 4.56e-12 Electroencephalogram traits; TGCT cis rs11190604 1.000 rs2295770 chr10:102239829 G/A cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7586879 0.681 rs6705446 chr2:25118608 T/C cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs78487399 0.808 rs6708735 chr2:43731354 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.49 0.37 1.59e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs595982 0.546 rs9941490 chr19:49396737 G/A cg11637076 chr19:49575188 KCNA7 -0.44 -5.23 -0.43 6.99e-7 Red cell distribution width; TGCT cis rs9910055 1.000 rs9910055 chr17:42283037 C/T cg19774624 chr17:42201019 HDAC5 -0.85 -8.21 -0.59 2.45e-13 Total body bone mineral density; TGCT cis rs10501293 0.789 rs4755690 chr11:43054680 A/G cg03447554 chr11:43094025 NA 0.45 6.58 0.51 1.2e-9 Cognitive performance; TGCT cis rs10464366 1.000 rs10464366 chr7:39121500 A/T cg15212455 chr7:39170539 POU6F2 -0.23 -5.05 -0.41 1.56e-6 IgG glycosylation; TGCT cis rs875971 1.000 rs1144895 chr7:65541307 C/G cg18876405 chr7:65276391 NA -0.35 -5.19 -0.42 8.26e-7 Aortic root size; TGCT cis rs10791323 0.604 rs2851116 chr11:133705759 G/A cg03690763 chr11:133734501 NA -0.35 -5.34 -0.43 4.31e-7 Childhood ear infection; TGCT cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg10883421 chr6:151773342 RMND1;C6orf211 0.65 6.39 0.5 3.07e-9 Menarche (age at onset); TGCT cis rs6840360 0.642 rs2724577 chr4:152354905 C/G cg17479576 chr4:152424074 FAM160A1 -0.62 -5.89 -0.47 3.32e-8 Intelligence (multi-trait analysis); TGCT cis rs4478858 0.735 rs10798843 chr1:31797094 A/G cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs9486719 1.000 rs12529248 chr6:96895377 T/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT trans rs561341 0.700 rs79272796 chr17:30226974 T/C cg20587970 chr11:113659929 NA -0.59 -8.99 -0.63 3.41e-15 Hip circumference adjusted for BMI; TGCT cis rs7714584 1.000 rs12656600 chr5:150311872 A/G cg22134413 chr5:150180641 NA 1.04 7.46 0.56 1.34e-11 Crohn's disease; TGCT cis rs17221829 0.739 rs55812948 chr11:89446332 T/C cg02982614 chr11:89391479 FOLH1B -0.29 -5.09 -0.42 1.3e-6 Anxiety in major depressive disorder; TGCT cis rs950169 0.922 rs8037078 chr15:84818871 A/G cg11189052 chr15:85197271 WDR73 -0.81 -6.5 -0.5 1.78e-9 Schizophrenia; TGCT trans rs916888 0.821 rs199507 chr17:44858855 A/G cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs62103177 0.673 rs4438371 chr18:77615988 C/T cg05926928 chr17:57297772 GDPD1 1.06 10.79 0.7 1.52e-19 Opioid sensitivity; TGCT cis rs4285028 0.948 rs7640872 chr3:121697168 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.68 -5.37 -0.43 3.7e-7 Multiple sclerosis; TGCT cis rs13191362 0.810 rs66921603 chr6:162996982 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg06873352 chr17:61820015 STRADA 0.56 6.19 0.49 8.27e-9 Prudent dietary pattern; TGCT cis rs9467711 0.606 rs68072215 chr6:26377927 T/C cg16898833 chr6:26189333 HIST1H4D 1.1 5.3 0.43 5.01e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.654 rs903705 chr8:58128185 T/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT trans rs6089829 0.962 rs6122350 chr20:61664617 A/G cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467773 1.000 rs10484442 chr6:26555879 A/G cg26531700 chr6:26746687 NA 0.49 4.76 0.39 5.3e-6 Intelligence (multi-trait analysis); TGCT cis rs713587 0.520 rs512419 chr2:25310155 G/T cg01884057 chr2:25150051 NA -0.26 -4.87 -0.4 3.36e-6 Body mass index in non-asthmatics; TGCT cis rs7412746 0.611 rs66847267 chr1:150875173 C/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT trans rs7613875 0.600 rs2856237 chr3:50158774 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.85 -8.89 -0.62 6.01e-15 Body mass index; TGCT cis rs8177253 1.000 rs8177261 chr3:133480588 A/C cg16414030 chr3:133502952 NA -0.61 -9.65 -0.66 8.74e-17 Iron status biomarkers; TGCT cis rs2404602 0.716 rs67204011 chr15:76846555 C/T cg26408565 chr15:76604113 ETFA -0.36 -4.71 -0.39 6.44e-6 Blood metabolite levels; TGCT cis rs11175492 0.528 rs61931629 chr12:65027969 G/A cg18624581 chr12:65153313 GNS -0.84 -4.64 -0.38 8.75e-6 Platelet count; TGCT cis rs2072499 0.966 rs2842864 chr1:156159217 G/A cg25208724 chr1:156163844 SLC25A44 1.14 16.72 0.83 1.43e-33 Testicular germ cell tumor; TGCT cis rs2742417 1.000 rs2742438 chr3:45743390 G/T cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs8077577 0.945 rs997315 chr17:18085286 A/G cg09161412 chr17:18057145 MYO15A -0.64 -5.2 -0.42 7.92e-7 Obesity-related traits; TGCT cis rs2832077 0.527 rs1048546 chr21:30244877 G/T cg24692254 chr21:30365293 RNF160 -0.57 -4.82 -0.4 4.13e-6 Cognitive test performance; TGCT cis rs4853012 0.539 rs9789534 chr2:74362990 A/T cg05890377 chr2:74357713 NA 0.42 4.92 0.4 2.68e-6 Gestational age at birth (maternal effect); TGCT cis rs1371867 0.846 rs1660326 chr8:101290447 G/A cg06002616 chr8:101225028 SPAG1 -0.57 -6.8 -0.52 3.95e-10 Atrioventricular conduction; TGCT cis rs854765 0.647 rs712267 chr17:18021607 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.71 7.37 0.55 2.15e-11 Total body bone mineral density; TGCT cis rs2730245 0.592 rs2657385 chr7:158649373 A/G cg24397884 chr7:158709396 WDR60 0.36 4.58 0.38 1.11e-5 Height; TGCT cis rs1403694 0.515 rs1622922 chr3:186449884 C/T cg12454167 chr3:186435060 KNG1 0.46 7.19 0.54 5.47e-11 Blood protein levels; TGCT cis rs1867631 1.000 rs6665859 chr1:67077555 A/T cg13052034 chr1:66999238 SGIP1 0.59 5.11 0.42 1.18e-6 Menopause (age at onset); TGCT cis rs155076 1.000 rs261431 chr13:21865738 A/G cg14456004 chr13:21872349 NA 1.29 10.88 0.7 9.16e-20 White matter hyperintensity burden; TGCT cis rs6988636 0.579 rs28528232 chr8:124189308 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs514406 0.505 rs269287 chr1:53168842 T/C cg25767906 chr1:53392781 SCP2 -0.44 -4.83 -0.4 3.93e-6 Monocyte count; TGCT cis rs1891275 0.515 rs2153653 chr10:93495926 T/A cg07889827 chr10:93443413 NA -0.32 -6.89 -0.53 2.53e-10 Intelligence (multi-trait analysis); TGCT cis rs2075371 1.000 rs2598286 chr7:133976029 G/A cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.68e-9 Mean platelet volume; TGCT cis rs1568889 0.838 rs7952717 chr11:28261658 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 10.85 0.7 1.1e-19 Bipolar disorder; TGCT cis rs2075371 0.796 rs1643040 chr7:134011703 G/C cg11752832 chr7:134001865 SLC35B4 0.72 6.22 0.49 7.09e-9 Mean platelet volume; TGCT cis rs17376456 0.935 rs10036891 chr5:93171738 T/A cg25358565 chr5:93447407 FAM172A 0.95 6.14 0.48 1.04e-8 Diabetic retinopathy; TGCT cis rs6964587 0.626 rs6972945 chr7:91549576 C/G cg17063962 chr7:91808500 NA -0.76 -7.25 -0.55 3.94e-11 Breast cancer; TGCT cis rs1372520 0.873 rs2583990 chr4:90771499 A/G cg15133208 chr4:90757351 SNCA -0.52 -6.26 -0.49 5.61e-9 Neuroticism; TGCT cis rs4563143 0.514 rs112540771 chr19:29316100 C/T cg14983838 chr19:29218262 NA 0.68 4.91 0.4 2.81e-6 Methadone dose in opioid dependence; TGCT cis rs6714710 0.603 rs6757357 chr2:98491750 T/C cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs77106637 0.860 rs75896506 chr11:72429579 G/A cg17176195 chr11:71639533 LOC100133315;RNF121 0.66 4.44 0.37 2e-5 Type 2 diabetes; TGCT cis rs34526934 0.524 rs1124052 chr2:177040084 G/A cg14324370 chr2:177042789 NA -0.92 -8.73 -0.62 1.45e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs6921919 0.583 rs7775132 chr6:28347013 T/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs425277 0.958 rs262660 chr1:2086757 A/G cg24578937 chr1:2090814 PRKCZ 0.32 8.19 0.59 2.64e-13 Height; TGCT cis rs17253792 0.749 rs17747301 chr14:56125030 C/G cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg18765753 chr7:1198926 ZFAND2A -0.53 -6.51 -0.5 1.71e-9 Longevity;Endometriosis; TGCT cis rs950776 0.518 rs12910978 chr15:78810017 A/G cg06917634 chr15:78832804 PSMA4 0.97 9.62 0.65 1.05e-16 Sudden cardiac arrest; TGCT cis rs9443189 0.723 rs2748947 chr6:76437921 C/T cg01950844 chr6:76311363 SENP6 -0.67 -4.69 -0.39 7.18e-6 Prostate cancer; TGCT cis rs3796352 1.000 rs13069006 chr3:52973305 G/C cg15956490 chr3:53032818 SFMBT1 0.61 6.11 0.48 1.17e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4242434 0.672 rs2404654 chr8:22484949 T/C cg03733263 chr8:22462867 KIAA1967 0.96 13.43 0.77 6.21e-26 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7258465 0.965 rs7256534 chr19:18586791 C/T cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs10504229 1.000 rs67388517 chr8:58176617 C/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10832169 0.933 rs2697821 chr11:14079358 G/A cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.46e-5 Blood protein levels; TGCT cis rs2486288 0.656 rs11632920 chr15:45551264 C/T cg26924012 chr15:45694286 SPATA5L1 -0.7 -7.09 -0.54 8.85e-11 Glomerular filtration rate; TGCT cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6782228 0.675 rs2253151 chr3:128330137 T/C cg15113803 chr3:129247119 RHO -0.16 -4.5 -0.37 1.57e-5 Monocyte count;Myeloid white cell count;Sum neutrophil eosinophil counts;Lymphocyte percentage of white cells;White blood cell count;Neutrophil count;Granulocyte count;Sum basophil neutrophil counts; TGCT cis rs41271951 0.512 rs41266632 chr1:151042980 C/T cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs9527 0.590 rs10883843 chr10:104947493 C/G cg15744005 chr10:104629667 AS3MT -0.4 -4.63 -0.38 9.04e-6 Arsenic metabolism; TGCT cis rs9788682 1.000 rs35212593 chr15:78831826 G/A cg24631222 chr15:78858424 CHRNA5 0.92 7.57 0.56 7.51e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9677476 0.908 rs7598478 chr2:232115887 C/T cg07929768 chr2:232055508 NA 0.3 4.44 0.37 1.97e-5 Food antigen IgG levels; TGCT cis rs6723226 0.806 rs6543658 chr2:32718849 G/A cg02381751 chr2:32503542 YIPF4 0.51 4.68 0.39 7.34e-6 Intelligence (multi-trait analysis); TGCT cis rs7959452 0.557 rs7980883 chr12:69778914 C/T cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs8031584 0.872 rs11634761 chr15:31243173 A/C cg08704250 chr15:31115839 NA -0.36 -4.99 -0.41 1.98e-6 Huntington's disease progression; TGCT cis rs7666738 0.830 rs1813642 chr4:98852225 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.59 0.56 6.56e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs651907 0.535 rs11712309 chr3:101519097 T/C cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs2153535 0.580 rs9379210 chr6:8461928 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg15242686 chr22:24348715 GSTTP1 0.42 5.57 0.45 1.54e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12220898 0.749 rs10776553 chr10:50482929 C/T cg09603381 chr10:49954066 WDFY4 0.38 4.52 0.38 1.4e-5 Inflammatory biomarkers; TGCT cis rs9409154 0.823 rs56001232 chr9:118100133 C/T cg14094498 chr9:119000864 PAPPA 0.26 4.69 0.39 7.2e-6 Visceral adipose tissue adjusted for BMI; TGCT cis rs1483890 0.723 rs900669 chr3:69406802 T/A cg22125112 chr3:69402811 FRMD4B 0.29 4.71 0.39 6.53e-6 Resting heart rate; TGCT cis rs6840360 0.550 rs7689266 chr4:152561048 T/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs4642101 0.560 rs4535210 chr3:12839617 T/G cg05775895 chr3:12838266 CAND2 0.67 7.07 0.54 9.95e-11 QRS complex (12-leadsum); TGCT trans rs365060 0.822 rs260691 chr2:109580638 C/T cg13735819 chr19:2253850 JSRP1 -0.7 -6.64 -0.51 8.97e-10 Beard thickness; TGCT cis rs8177253 0.763 rs12769 chr3:133474328 G/A cg11941060 chr3:133502564 NA -0.25 -5.23 -0.43 6.97e-7 Iron status biomarkers; TGCT cis rs9372498 0.536 rs62421536 chr6:118727972 G/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.4 4.62e-6 Diastolic blood pressure; TGCT cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.89 0.47 3.34e-8 Height; TGCT cis rs79390637 1 rs79390637 chr11:47456867 C/A cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Intraocular pressure; TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg02073558 chr3:44770973 ZNF501 0.61 5.94 0.47 2.73e-8 Depressive symptoms; TGCT cis rs3809566 1.000 rs4775612 chr15:63332157 T/C cg00520135 chr15:63333846 TPM1 -0.44 -5.46 -0.44 2.44e-7 Platelet count; TGCT cis rs4805272 0.849 rs17591205 chr19:29321469 T/C cg15000279 chr19:29285009 NA -0.53 -5.71 -0.46 7.96e-8 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs7666738 0.753 rs9991512 chr4:99007205 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11948739 0.610 rs2419754 chr5:130252688 T/C cg08523029 chr5:130500466 HINT1 0.59 4.81 0.4 4.32e-6 Pediatric bone mineral content (hip); TGCT cis rs7312933 0.737 rs10880261 chr12:42573822 T/C cg19980929 chr12:42632907 YAF2 0.46 6.3 0.49 4.75e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1799949 1.000 rs8176289 chr17:41206056 T/C cg10047753 chr17:41438598 NA 0.91 8.44 0.6 6.86e-14 Menopause (age at onset); TGCT cis rs28595532 0.920 rs115706007 chr4:119733638 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs896854 0.812 rs12546365 chr8:95911477 T/C cg13393036 chr8:95962371 TP53INP1 -0.58 -7.84 -0.58 1.79e-12 Type 2 diabetes; TGCT cis rs9325144 0.602 rs11169100 chr12:39077861 G/T cg26384229 chr12:38710491 ALG10B -0.55 -5.09 -0.42 1.28e-6 Morning vs. evening chronotype; TGCT cis rs1005277 0.579 rs2472181 chr10:38386764 T/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs6459788 0.657 rs887627 chr7:157237391 G/A cg03453431 chr7:157225567 NA -0.4 -5.8 -0.46 5.3e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs12048904 0.512 rs932798 chr1:101249355 G/C cg15686842 chr1:101360669 SLC30A7;EXTL2 -0.72 -5.76 -0.46 6.32e-8 Multiple sclerosis; TGCT cis rs2153535 0.580 rs7341381 chr6:8470537 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg12310025 chr6:25882481 NA -0.6 -5.29 -0.43 5.28e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 1.000 rs12126607 chr1:76217097 G/A cg10523679 chr1:76189770 ACADM 0.89 9.53 0.65 1.72e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9325144 0.671 rs7306605 chr12:38730471 C/T cg26384229 chr12:38710491 ALG10B 0.61 5.58 0.45 1.46e-7 Morning vs. evening chronotype; TGCT cis rs1635 0.512 rs73742545 chr6:28319023 T/G cg15743358 chr6:28303923 ZNF323 -1.25 -6.08 -0.48 1.37e-8 Schizophrenia; TGCT cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg17554472 chr22:41940697 POLR3H -0.46 -4.69 -0.39 7.09e-6 Vitiligo; TGCT cis rs981844 1.000 rs2579916 chr4:154659972 G/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs9467773 0.587 rs9467722 chr6:26352566 T/C cg15659132 chr6:26577336 NA -0.51 -5.34 -0.43 4.33e-7 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.537 rs11611326 chr12:38547958 C/A cg13010199 chr12:38710504 ALG10B 0.62 5.02 0.41 1.74e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12908161 1.000 rs35316992 chr15:85248133 A/G cg11189052 chr15:85197271 WDR73 0.75 6.29 0.49 5.02e-9 Schizophrenia; TGCT cis rs7552404 0.924 rs1303169 chr1:76195041 T/C cg03433033 chr1:76189801 ACADM 0.77 9.31 0.64 5.74e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs250677 0.687 rs40523 chr5:148444186 A/T cg23229984 chr5:148520753 ABLIM3 -0.22 -5.16 -0.42 9.35e-7 Breast cancer; TGCT cis rs2836974 0.644 rs4818017 chr21:40690561 G/T cg06238570 chr21:40685208 BRWD1 -0.81 -8.52 -0.61 4.45e-14 Cognitive function; TGCT cis rs7208859 0.623 rs58908911 chr17:29244558 C/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.72 -0.39 6.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6912958 0.500 rs4706287 chr6:87806496 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.69 -6.45 -0.5 2.28e-9 Monocyte percentage of white cells; TGCT cis rs11098499 0.954 rs6822679 chr4:120402702 A/C cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs112217694 1.000 rs112217694 chr4:104641064 G/C cg24090629 chr4:104641072 TACR3 -0.95 -4.8 -0.4 4.45e-6 Menarche (age at onset); TGCT cis rs113084984 0.642 rs35417544 chr2:11680403 C/T cg25804072 chr2:10829725 NOL10 0.53 4.62 0.38 9.36e-6 Breast cancer; TGCT cis rs8177253 0.931 rs8177256 chr3:133480276 G/T cg11941060 chr3:133502564 NA -0.29 -6.14 -0.48 1.02e-8 Iron status biomarkers; TGCT cis rs7267979 1.000 rs6107045 chr20:25441936 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs67460515 0.892 rs73026974 chr3:160963231 A/C cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT cis rs116095464 0.558 rs10060089 chr5:205565 G/A cg12570787 chr5:219185 SDHA;CCDC127 0.71 4.51 0.38 1.48e-5 Breast cancer; TGCT trans rs916888 0.821 rs199525 chr17:44847834 T/G cg22433210 chr17:43662623 NA 0.99 7.14 0.54 7.1e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4253772 0.637 rs9627402 chr22:46702586 C/T cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs7666738 0.753 rs7657644 chr4:99057734 T/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7208859 0.623 rs9911997 chr17:29124648 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17376456 0.877 rs12374470 chr5:93481046 A/G cg21475434 chr5:93447410 FAM172A 0.64 4.71 0.39 6.42e-6 Diabetic retinopathy; TGCT cis rs6952809 0.532 rs7803015 chr7:2432143 G/A cg23289794 chr7:2394357 EIF3B -0.83 -7.09 -0.54 8.92e-11 Multiple sclerosis; TGCT cis rs11190604 1.000 rs11190569 chr10:102227409 C/T cg23241863 chr10:102295624 HIF1AN 0.59 4.51 0.38 1.46e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6952808 0.723 rs4721295 chr7:2036669 G/T cg22963979 chr7:1858916 MAD1L1 0.44 7.43 0.56 1.54e-11 Bipolar disorder and schizophrenia; TGCT cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.9 -6.48 -0.5 1.91e-9 Gut microbiome composition (summer); TGCT cis rs7772486 0.641 rs67882056 chr6:146416301 T/C cg05347473 chr6:146136440 FBXO30 0.55 5.07 0.41 1.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs61990749 0.544 rs2544566 chr14:78181738 C/G cg02301378 chr14:78227641 SNW1;C14orf178 0.63 4.62 0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs514406 0.644 rs928451 chr1:53195800 A/G cg01802117 chr1:53393560 SCP2 0.42 4.92 0.4 2.69e-6 Monocyte count; TGCT cis rs7918232 0.941 rs10829195 chr10:27431564 G/A cg14442939 chr10:27389572 ANKRD26 0.72 5.35 0.43 4.16e-7 Breast cancer; TGCT cis rs9677476 0.516 rs10202608 chr2:232050653 A/G cg07929768 chr2:232055508 NA 0.32 5.05 0.41 1.53e-6 Food antigen IgG levels; TGCT cis rs2070433 0.752 rs11701058 chr21:47776382 T/C cg12379764 chr21:47803548 PCNT 0.66 5.61 0.45 1.25e-7 Lymphocyte counts; TGCT cis rs7552404 0.731 rs6699682 chr1:76340123 A/G cg03433033 chr1:76189801 ACADM -0.77 -7.94 -0.58 1.01e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs79349575 0.783 rs12453394 chr17:46994970 G/A cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs12780845 0.540 rs2273735 chr10:17216419 T/C cg01003015 chr10:17271136 VIM 0.53 4.64 0.38 8.56e-6 Homocysteine levels; TGCT cis rs1865760 1.000 rs6938233 chr6:25914077 C/T cg16482183 chr6:26056742 HIST1H1C 0.53 4.72 0.39 6.29e-6 Height; TGCT cis rs28595532 0.920 rs114659035 chr4:119740028 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs7914558 1.000 rs4917994 chr10:104811699 C/T cg15744005 chr10:104629667 AS3MT -0.38 -4.69 -0.39 7.04e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg18538332 chr22:24372958 LOC391322 -0.82 -9.23 -0.64 9.18e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs835154 1.000 rs2934814 chr5:14872689 C/T cg14843632 chr5:14870594 ANKH 0.46 7.21 0.54 4.86e-11 Blood metabolite levels; TGCT cis rs2180341 1.000 rs3798850 chr6:127613966 C/T cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs317865 0.737 rs16893097 chr4:16156964 G/T cg04764131 chr4:16228633 TAPT1;FLJ39653 0.79 5.38 0.44 3.5e-7 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs7666738 0.830 rs28451101 chr4:99001190 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg08859206 chr1:53392774 SCP2 -0.46 -7.57 -0.56 7.3e-12 Monocyte count; TGCT cis rs7647973 0.710 rs2029591 chr3:49646981 C/T cg03060546 chr3:49711283 APEH -0.63 -5.19 -0.42 8.41e-7 Menarche (age at onset); TGCT cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs10992471 0.603 rs11794346 chr9:95247288 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -5.84 -0.46 4.31e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.94 -0.41 2.5e-6 Prudent dietary pattern; TGCT cis rs524281 0.861 rs7946917 chr11:65956577 A/G cg00563793 chr11:65837595 PACS1 0.52 4.5 0.37 1.55e-5 Electroencephalogram traits; TGCT cis rs7772486 0.875 rs9322046 chr6:146393625 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.86 0.4 3.48e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs887829 0.507 rs10929301 chr2:234663649 C/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.45 -0.37 1.92e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs2710642 0.962 rs1828398 chr2:63034870 A/G cg17519650 chr2:63277830 OTX1 -0.64 -5.86 -0.47 3.97e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs7027203 0.828 rs7037960 chr9:96584028 G/A cg14396892 chr9:96623032 NA -0.29 -6.22 -0.49 7.08e-9 DNA methylation (variation); TGCT cis rs9467773 1.000 rs9393732 chr6:26530898 G/A cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.572 rs17032440 chr3:10169819 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 0.46 5.74 0.46 6.85e-8 Alzheimer's disease; TGCT cis rs9341808 0.718 rs2874829 chr6:80856097 A/G cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs7226408 0.857 rs11664002 chr18:34526377 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.73 0.39 6e-6 Obesity-related traits; TGCT cis rs2204008 0.774 rs7959048 chr12:37948276 T/A cg26384229 chr12:38710491 ALG10B 0.87 7.79 0.57 2.32e-12 Bladder cancer; TGCT cis rs2404602 0.735 rs2468130 chr15:76796496 T/C cg06069100 chr15:77574588 SGK269 0.26 4.64 0.38 8.81e-6 Blood metabolite levels; TGCT cis rs12541335 0.639 rs11135995 chr8:22200148 C/T cg07298985 chr8:22133076 PIWIL2 -0.33 -5.22 -0.42 7.19e-7 Hypertriglyceridemia; TGCT cis rs72627509 0.904 rs17081935 chr4:57823476 C/T cg26694713 chr4:57773883 REST 0.73 6.49 0.5 1.89e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg04025307 chr7:1156635 C7orf50 0.24 5.58 0.45 1.43e-7 Longevity;Endometriosis; TGCT cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg11062466 chr8:58055876 NA 0.44 4.62 0.38 9.46e-6 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.960 rs2269855 chr17:29482878 G/A cg24425628 chr17:29625626 OMG;NF1 0.48 7.48 0.56 1.16e-11 Hip circumference; TGCT cis rs2762353 0.806 rs6909187 chr6:25785925 C/T cg03517284 chr6:25882590 NA 0.48 4.86 0.4 3.42e-6 Blood metabolite levels; TGCT cis rs425277 0.606 rs262653 chr1:2090095 T/G cg03732007 chr1:2071316 PRKCZ 0.28 6.63 0.51 9.05e-10 Height; TGCT cis rs1401999 0.690 rs3805112 chr3:183645662 C/T cg01324343 chr3:183735012 ABCC5 0.68 8.01 0.58 7.25e-13 Anterior chamber depth; TGCT trans rs7248779 0.532 rs10153475 chr19:2413961 G/C cg25835954 chr13:50160062 RCBTB1 0.76 7.04 0.53 1.15e-10 Cortisol levels (saliva); TGCT cis rs6570726 0.791 rs11759979 chr6:145918881 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs13242816 1.000 rs62471202 chr7:116112562 G/A cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs7698623 0.867 rs4693191 chr4:88797873 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs4595586 0.545 rs1588970 chr12:39403122 C/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs597539 0.518 rs35093305 chr11:68730729 A/G cg21963583 chr11:68658836 MRPL21 0.35 5.76 0.46 6.33e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs13139024 chr4:99020700 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.765 rs7340412 chr2:99661148 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs6688613 0.685 rs10800276 chr1:166858941 A/G cg07049167 chr1:166818506 POGK -0.24 -5.25 -0.43 6.41e-7 Refractive astigmatism; TGCT cis rs9677476 0.517 rs62197322 chr2:232061520 A/G cg07929768 chr2:232055508 NA 0.3 4.83 0.4 4.01e-6 Food antigen IgG levels; TGCT cis rs9325144 0.555 rs4882359 chr12:38726679 T/C cg26384229 chr12:38710491 ALG10B 0.65 6.06 0.48 1.55e-8 Morning vs. evening chronotype; TGCT cis rs3617 0.625 rs2239548 chr3:52854186 A/C cg11645453 chr3:52864694 ITIH4 0.28 5.45 0.44 2.63e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg05738196 chr6:26577821 NA -0.5 -4.77 -0.39 5.05e-6 Schizophrenia; TGCT cis rs9467711 0.606 rs9348712 chr6:26366511 T/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs832540 0.629 rs6888317 chr5:56093307 A/G cg12311346 chr5:56204834 C5orf35 0.48 4.99 0.41 1.98e-6 Coronary artery disease; TGCT cis rs12681288 0.862 rs2701898 chr8:1020812 C/T cg06709756 chr8:1339049 NA -0.22 -4.45 -0.37 1.88e-5 Schizophrenia; TGCT cis rs2762353 0.935 rs1165196 chr6:25813150 A/G cg03264133 chr6:25882463 NA 0.52 5.35 0.43 4.04e-7 Blood metabolite levels; TGCT cis rs12200560 0.505 rs984519 chr6:97076223 A/G cg06623918 chr6:96969491 KIAA0776 -0.54 -4.64 -0.38 8.79e-6 Coronary heart disease; TGCT cis rs6459788 0.605 rs887628 chr7:157237589 G/A cg06271696 chr7:157225062 NA -0.29 -5.13 -0.42 1.07e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs4319547 0.695 rs10846746 chr12:122868696 C/T cg05707623 chr12:122985044 ZCCHC8 0.62 4.87 0.4 3.32e-6 Body mass index; TGCT cis rs7429990 0.896 rs7427648 chr3:48158239 C/T cg11946769 chr3:48343235 NME6 -0.56 -4.61 -0.38 9.72e-6 Educational attainment (years of education); TGCT trans rs1005277 0.579 rs2472183 chr10:38392495 T/G cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2404602 0.679 rs12900494 chr15:76912504 A/G cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.07e-6 Blood metabolite levels; TGCT trans rs1814175 0.529 rs10839396 chr11:49852406 G/T cg11707556 chr5:10655725 ANKRD33B 0.43 9.22 0.64 9.54e-16 Height; TGCT trans rs7615952 0.932 rs13086087 chr3:125646281 A/C cg07211511 chr3:129823064 LOC729375 -0.48 -8.02 -0.58 6.91e-13 Blood pressure (smoking interaction); TGCT cis rs9640161 0.830 rs11768108 chr7:150064150 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.7 0.39 6.68e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs2014572 0.967 rs7259978 chr19:57756129 C/T cg24459738 chr19:57751996 ZNF805 -0.54 -5.4 -0.44 3.21e-7 Hyperactive-impulsive symptoms; TGCT cis rs10504229 0.861 rs59873610 chr8:58172290 T/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs3785574 0.650 rs2070776 chr17:62007498 A/G cg11494091 chr17:61959527 GH2 -0.43 -7.51 -0.56 9.92e-12 Height; TGCT cis rs17384381 1.000 rs17384381 chr1:85897570 C/G cg16011679 chr1:85725395 C1orf52 0.75 6.05 0.48 1.62e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg07424592 chr7:64974309 NA 1.36 8.16 0.59 3.15e-13 Diabetic kidney disease; TGCT cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg02187348 chr16:89574699 SPG7 0.61 6.57 0.51 1.25e-9 Multiple myeloma (IgH translocation); TGCT cis rs9443645 0.901 rs9352664 chr6:79566162 G/T cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT trans rs7618501 0.966 rs13063621 chr3:49821625 T/C cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs1119179 chr3:40424929 A/C cg17264618 chr3:40429014 ENTPD3 -0.32 -4.76 -0.39 5.32e-6 Renal cell carcinoma; TGCT cis rs597539 0.580 rs7935851 chr11:68731122 A/G cg21862992 chr11:68658383 NA 0.44 6.0 0.47 2e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9894429 0.572 rs112417725 chr17:79578219 A/G cg18240062 chr17:79603768 NPLOC4 -0.56 -4.92 -0.4 2.67e-6 Eye color traits; TGCT cis rs4595586 0.545 rs12833238 chr12:39373898 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs12142240 0.698 rs72886911 chr1:46814352 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg18252515 chr7:66147081 NA -1.19 -7.51 -0.56 1.02e-11 Diabetic kidney disease; TGCT cis rs4654899 0.802 rs17416732 chr1:21256368 T/C cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs308403 0.568 rs309358 chr4:123653926 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.72 6.64 0.51 8.74e-10 Blood protein levels; TGCT cis rs7635838 0.617 rs2606731 chr3:11291615 A/C cg00170343 chr3:11313890 ATG7 0.67 6.23 0.49 6.74e-9 HDL cholesterol; TGCT cis rs698813 0.572 rs4953076 chr2:44480950 G/C cg00619915 chr2:44497795 NA -0.25 -5.7 -0.46 8.13e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs3091242 0.902 rs36003018 chr1:25784318 A/G cg09222892 chr1:25734099 RHCE 0.42 7.15 0.54 6.72e-11 Erythrocyte sedimentation rate; TGCT cis rs875971 0.862 rs778702 chr7:65864835 G/A cg11764359 chr7:65958608 NA 0.57 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs7208859 0.623 rs35916850 chr17:29011173 G/A cg14008862 chr17:28927542 LRRC37B2 0.84 5.1 0.42 1.22e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10489202 0.608 rs16828093 chr1:168078384 C/T cg24449463 chr1:168025552 DCAF6 -0.5 -5.13 -0.42 1.08e-6 Schizophrenia; TGCT cis rs9467711 0.516 rs501220 chr6:25873025 C/A cg03517284 chr6:25882590 NA -0.75 -5.06 -0.41 1.45e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2456568 0.802 rs8181578 chr11:93637442 G/A cg16099599 chr11:93583650 C11orf90 -0.4 -5.12 -0.42 1.13e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10479542 0.721 rs6894113 chr5:178974789 G/C cg19723775 chr5:179050963 HNRNPH1 0.48 4.84 0.4 3.86e-6 Lung cancer; TGCT cis rs7465272 0.500 rs7463655 chr8:143731034 G/C cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.79e-7 Bipolar disorder and schizophrenia; TGCT cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg16414030 chr3:133502952 NA -0.7 -11.62 -0.72 1.48e-21 Iron status biomarkers; TGCT cis rs3096299 0.781 rs2965819 chr16:89501030 G/T cg08392591 chr16:89556376 ANKRD11 -0.52 -4.81 -0.4 4.26e-6 Multiple myeloma (IgH translocation); TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg08736216 chr1:53307985 ZYG11A 0.24 4.63 0.38 8.98e-6 Monocyte count; TGCT cis rs7209700 0.638 rs4629025 chr17:45337435 A/T cg21624342 chr17:45890973 OSBPL7 0.18 5.01 0.41 1.86e-6 IgG glycosylation; TGCT cis rs35146811 0.735 rs11767968 chr7:99790971 G/A cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs4891159 0.756 rs8084155 chr18:74134952 A/G cg24786174 chr18:74118243 ZNF516 -0.61 -9.69 -0.66 7e-17 Longevity; TGCT cis rs7659604 0.676 rs7691955 chr4:122700462 A/T cg20573242 chr4:122745356 CCNA2 0.55 4.92 0.4 2.69e-6 Type 2 diabetes; TGCT cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs2153535 0.580 rs6597327 chr6:8482157 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs10028773 0.700 rs7690338 chr4:120256468 C/G cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Educational attainment; TGCT cis rs7208859 0.673 rs9889968 chr17:29220128 C/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7726839 0.540 rs72705102 chr5:659437 T/C cg16624210 chr5:671434 TPPP 0.42 4.69 0.39 7.07e-6 Obesity-related traits; TGCT cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs7267979 0.789 rs2260197 chr20:25284343 T/C cg13486641 chr20:25479848 NINL -0.16 -4.57 -0.38 1.17e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7914558 1.000 rs7071373 chr10:104771922 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.97 -0.41 2.21e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9916302 0.904 rs4511574 chr17:37532916 A/G cg15445000 chr17:37608096 MED1 0.33 4.72 0.39 6.21e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg20607798 chr8:58055168 NA 0.64 5.89 0.47 3.47e-8 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.754 rs9386132 chr6:146140751 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.11 0.42 1.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs185694 1.000 rs185694 chr13:30885223 C/T cg07600127 chr13:30881527 KATNAL1 0.85 6.96 0.53 1.77e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs6912958 0.515 rs381782 chr6:88040649 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.45 5.88 0.47 3.48e-8 Monocyte percentage of white cells; TGCT cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg09323728 chr8:95962352 TP53INP1 -0.53 -6.88 -0.53 2.67e-10 Type 2 diabetes; TGCT cis rs12681287 1.000 rs7833786 chr8:87271374 C/T cg27223183 chr8:87520930 FAM82B 0.76 5.5 0.44 2.11e-7 Caudate activity during reward; TGCT trans rs1814175 0.562 rs1794130 chr11:49903764 T/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs56235845 0.694 rs4532376 chr5:176774403 G/A cg17509989 chr5:176798049 RGS14 0.57 7.78 0.57 2.49e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs4918072 0.637 rs61861137 chr10:105613383 A/G cg11005552 chr10:105648138 OBFC1 0.4 5.13 0.42 1.1e-6 Coronary artery disease; TGCT cis rs6582630 0.502 rs12815350 chr12:38439921 A/T cg26384229 chr12:38710491 ALG10B 0.85 7.59 0.56 6.74e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs6940638 0.688 rs9393795 chr6:27217719 G/C cg15659132 chr6:26577336 NA -0.57 -5.43 -0.44 2.81e-7 Intelligence (multi-trait analysis); TGCT cis rs1505368 0.532 rs2888093 chr2:213328348 G/A cg20637307 chr2:213403960 ERBB4 0.68 7.1 0.54 8.72e-11 Symmetrical dimethylarginine levels; TGCT cis rs752010 0.714 rs10789403 chr1:42085869 G/A cg06885757 chr1:42089581 HIVEP3 0.25 4.51 0.38 1.45e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs875971 0.964 rs6945032 chr7:65922486 C/T cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs6461049 0.734 rs1558465 chr7:2151398 G/C cg22963979 chr7:1858916 MAD1L1 -0.42 -6.64 -0.51 8.7e-10 Schizophrenia; TGCT cis rs6684514 1.000 rs10908498 chr1:156278175 T/C cg20302342 chr1:156215951 PAQR6 0.36 4.77 0.39 5.1e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs968451 0.756 rs1007117 chr22:39675770 G/T cg17798944 chr22:39715225 SNORD43;RPL3 0.74 7.55 0.56 8e-12 Primary biliary cholangitis; TGCT cis rs1903068 0.853 rs10012701 chr4:56002776 A/G cg16572876 chr4:56024045 NA 0.42 4.79 0.39 4.75e-6 Endometriosis; TGCT cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs9868809 0.772 rs9883469 chr3:48719637 G/A cg00383909 chr3:49044727 WDR6 1.24 5.91 0.47 3.1e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs12643440 0.503 rs7699243 chr4:17159265 T/G cg22650099 chr4:17144496 NA -0.43 -4.48 -0.37 1.65e-5 Metabolite levels (Pyroglutamine); TGCT cis rs11931598 0.511 rs4689576 chr4:7025523 T/C cg26116260 chr4:7069785 GRPEL1 0.59 5.52 0.44 1.85e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs35306767 0.903 rs11253475 chr10:907262 C/A cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs873946 0.648 rs12782123 chr10:134554662 G/A cg26818010 chr10:134567672 INPP5A -0.37 -5.03 -0.41 1.69e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4478858 0.746 rs7520439 chr1:31688721 G/C cg00250761 chr1:31883323 NA 0.29 4.78 0.39 4.9e-6 Alcohol dependence; TGCT cis rs9325144 0.647 rs7316392 chr12:39064381 T/G cg10518543 chr12:38710700 ALG10B -0.49 -4.59 -0.38 1.05e-5 Morning vs. evening chronotype; TGCT cis rs4930561 0.714 rs1540209 chr11:67928520 A/C cg04465784 chr11:67976953 SUV420H1 -0.41 -5.84 -0.46 4.35e-8 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT trans rs17471911 0.708 rs74663457 chr10:100762323 A/G cg03484267 chr2:207988651 KLF7 -0.53 -6.79 -0.52 4.24e-10 Neuroticism; TGCT cis rs9394841 0.692 rs3218108 chr6:41902655 C/T cg08135965 chr6:41755394 TOMM6 0.59 5.46 0.44 2.52e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs71435601 0.699 rs515135 chr2:21286057 T/C cg16723488 chr2:21266947 APOB 0.63 4.64 0.38 8.8e-6 Cholesterol, total; TGCT cis rs6665290 0.669 rs3795445 chr1:227180947 A/C cg10327440 chr1:227177885 CDC42BPA -0.89 -14.71 -0.8 5.67e-29 Myeloid white cell count; TGCT cis rs2658782 1.000 rs2658782 chr11:93166731 T/G cg18152523 chr11:93063302 CCDC67 -0.64 -5.15 -0.42 9.9e-7 Pulmonary function decline; TGCT cis rs3617 0.539 rs9825369 chr3:52953311 T/C cg10802521 chr3:52805072 NEK4 0.55 6.42 0.5 2.67e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4689388 0.853 rs11729672 chr4:6293838 A/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs73058052 0.597 rs7254718 chr19:50073226 A/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.66 5.76 0.46 6.17e-8 Fibrinogen levels; TGCT cis rs9467711 0.720 rs9348716 chr6:26375658 G/A cg10795676 chr6:26370623 BTN3A2 -0.47 -4.77 -0.39 5e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs797680 0.822 rs942196 chr1:93802264 T/A cg17826107 chr1:92977322 EVI5 -0.23 -5.07 -0.41 1.4e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6735179 0.641 rs10164792 chr2:1753375 G/A cg08534653 chr2:1747700 PXDN 0.54 4.54 0.38 1.34e-5 Response to antipsychotic treatment; TGCT cis rs2404602 0.692 rs35999717 chr15:77193367 G/C cg22467129 chr15:76604101 ETFA -0.48 -5.45 -0.44 2.58e-7 Blood metabolite levels; TGCT trans rs1814175 0.935 rs6485999 chr11:49658986 G/C cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs3782455 1.000 rs16943545 chr12:114406337 T/C cg11813512 chr12:114660791 NA -0.59 -4.7 -0.39 6.79e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1982963 0.950 rs2645749 chr14:52502795 C/A cg10843707 chr14:52510701 NID2 -0.42 -6.47 -0.5 2.07e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs240764 0.853 rs10457809 chr6:100984400 C/T cg21058520 chr6:100914733 NA 0.35 4.63 0.38 9.07e-6 Neuroticism; TGCT cis rs35146811 0.806 rs1534310 chr7:99699169 A/T cg13334819 chr7:99746414 C7orf59 -0.81 -6.92 -0.53 2.13e-10 Coronary artery disease; TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs7119 0.717 rs8033654 chr15:77825250 T/C cg27398640 chr15:77910606 LINGO1 -0.26 -4.73 -0.39 6.02e-6 Type 2 diabetes; TGCT cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg08439880 chr3:133502540 NA 0.35 6.91 0.53 2.3e-10 Iron status biomarkers; TGCT cis rs6840360 0.571 rs4696271 chr4:152509118 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs10488084 0.892 rs10281148 chr7:29977943 C/G cg19198568 chr7:28997866 TRIL 0.75 4.55 0.38 1.27e-5 Estradiol levels; TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg05215272 chr17:6899095 ALOX12 0.56 6.72 0.52 6e-10 Tonsillectomy; TGCT cis rs66573146 1.000 rs67067921 chr4:6984341 A/T cg05069807 chr4:6945702 TBC1D14 0.35 4.94 0.41 2.51e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs11264213 0.901 rs2791962 chr1:36371168 T/C cg07093915 chr1:36184400 C1orf216 0.66 4.47 0.37 1.73e-5 Schizophrenia; TGCT cis rs1005277 0.505 rs200910 chr10:38108176 C/T cg25427524 chr10:38739819 LOC399744 -0.37 -7.41 -0.55 1.75e-11 Extrinsic epigenetic age acceleration; TGCT cis rs11030122 0.547 rs10835333 chr11:3957766 A/G cg18678763 chr11:4115507 RRM1 -0.4 -4.9 -0.4 2.95e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs7772486 0.686 rs4896827 chr6:145953338 T/A cg23711669 chr6:146136114 FBXO30 0.85 9.48 0.65 2.33e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9796 0.870 rs28501589 chr15:41282534 G/A cg18705301 chr15:41695430 NDUFAF1 -0.43 -5.68 -0.45 9.16e-8 Menopause (age at onset); TGCT cis rs9911578 1.000 rs2531729 chr17:56539890 C/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.21 -0.49 7.48e-9 Intelligence (multi-trait analysis); TGCT cis rs6762 0.748 rs1130663 chr11:837582 G/A cg16425592 chr11:842748 TSPAN4;POLR2L -0.45 -4.55 -0.38 1.27e-5 Mean platelet volume; TGCT cis rs9911578 0.692 rs411988 chr17:56709034 G/A cg05425664 chr17:57184151 TRIM37 -0.49 -4.67 -0.39 7.63e-6 Intelligence (multi-trait analysis); TGCT cis rs3020736 0.500 rs5996111 chr22:42493902 C/T cg15557168 chr22:42548783 NA 0.22 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.26 -0.43 6.14e-7 Vitiligo; TGCT cis rs939658 1.000 rs17175798 chr15:79463960 A/G cg17916960 chr15:79447300 NA 0.54 8.98 0.63 3.58e-15 Refractive error; TGCT cis rs228437 0.565 rs7754115 chr6:134938220 A/G cg09872934 chr6:134495829 SGK1 -0.53 -4.6 -0.38 1.03e-5 Melanoma; TGCT trans rs57221529 0.766 rs1399381 chr5:589853 G/T cg11887960 chr12:57824829 NA 1.14 9.3 0.64 6.29e-16 Lung disease severity in cystic fibrosis; TGCT cis rs11122272 0.735 rs2572249 chr1:231514829 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs6912958 0.712 rs2754262 chr6:88405585 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.46 -4.48 -0.37 1.66e-5 Monocyte percentage of white cells; TGCT cis rs644799 0.542 rs10831416 chr11:95467220 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.56 5.62 0.45 1.18e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7647973 1.000 rs1982861 chr3:49577665 A/G cg05785598 chr3:49045655 WDR6 0.38 4.6 0.38 1.02e-5 Menarche (age at onset); TGCT cis rs2486012 1.000 rs1636879 chr1:44428680 G/C cg12908607 chr1:44402522 ARTN 0.75 5.88 0.47 3.49e-8 Intelligence (multi-trait analysis); TGCT cis rs17473412 1.000 rs111295980 chr5:122737257 G/A cg15125798 chr5:122621645 NA -0.55 -4.9 -0.4 2.98e-6 Total body bone mineral density; TGCT cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7631605 0.905 rs60490177 chr3:37254925 G/C cg17445812 chr3:36986805 TRANK1 0.2 4.43 0.37 2.01e-5 Cerebrospinal P-tau181p levels; TGCT cis rs12257961 0.549 rs11259613 chr10:15382515 A/C cg10616319 chr10:15468812 NA 0.28 5.17 0.42 9.08e-7 Selective IgA deficiency; TGCT cis rs9341808 0.718 rs4437429 chr6:80828592 A/G cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg20637647 chr7:64974828 NA 0.94 5.16 0.42 9.35e-7 Diabetic kidney disease; TGCT trans rs7819412 0.806 rs10113808 chr8:10926892 C/A cg15556689 chr8:8085844 FLJ10661 -0.78 -7.51 -0.56 9.97e-12 Triglycerides; TGCT cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg24503407 chr1:205819492 PM20D1 0.67 10.78 0.7 1.61e-19 Menarche (age at onset); TGCT cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg20302342 chr1:156215951 PAQR6 0.36 5.36 0.43 3.93e-7 Tonsillectomy; TGCT cis rs8103278 0.793 rs59093775 chr19:46374037 G/A cg14061069 chr19:46274453 DMPK -0.41 -5.33 -0.43 4.56e-7 Coronary artery disease; TGCT cis rs6933660 0.800 rs2046371 chr6:151754744 G/A cg10883421 chr6:151773342 RMND1;C6orf211 0.6 5.62 0.45 1.22e-7 Menarche (age at onset); TGCT cis rs2095921 1 rs2095921 chr1:11033322 C/G cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Male-pattern baldness; TGCT cis rs9329221 0.868 rs7831557 chr8:10280228 C/T cg21775007 chr8:11205619 TDH -0.46 -4.55 -0.38 1.24e-5 Neuroticism; TGCT cis rs1801251 1.000 rs1044480 chr2:233633736 A/G cg25237894 chr2:233734115 C2orf82 0.31 5.62 0.45 1.21e-7 Coronary artery disease; TGCT cis rs36051895 0.553 rs12338854 chr9:5057568 G/C cg02405213 chr9:5042618 JAK2 -0.78 -11.19 -0.71 1.59e-20 Pediatric autoimmune diseases; TGCT cis rs2832191 0.791 rs8134407 chr21:30476586 G/A cg08807101 chr21:30365312 RNF160 0.67 6.26 0.49 5.8e-9 Dental caries; TGCT cis rs2120019 1.000 rs35736167 chr15:75332002 T/G cg09165964 chr15:75287851 SCAMP5 -1.14 -10.22 -0.68 3.76e-18 Blood trace element (Zn levels); TGCT cis rs67311347 0.544 rs6762121 chr3:40355313 G/A cg17264618 chr3:40429014 ENTPD3 0.3 4.48 0.37 1.69e-5 Renal cell carcinoma; TGCT cis rs2673604 0.600 rs2442975 chr8:133415445 T/A cg05740582 chr8:133573933 HPYR1 -0.31 -4.48 -0.37 1.65e-5 Interleukin-8 levels; TGCT cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Vitiligo; TGCT cis rs9611565 0.694 rs11090056 chr22:42095904 A/C cg17554472 chr22:41940697 POLR3H 0.46 4.91 0.4 2.82e-6 Vitiligo; TGCT cis rs6831352 0.918 rs17218141 chr4:100055908 T/C cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs7666738 0.830 rs13110498 chr4:98959150 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10489525 0.687 rs61811044 chr1:115350808 C/T cg12756093 chr1:115239321 AMPD1 -0.49 -4.51 -0.38 1.47e-5 Autism; TGCT cis rs79387448 0.745 rs17027421 chr2:103159882 A/G cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs708547 0.836 rs1612191 chr4:57724320 A/C cg25525207 chr4:57843836 C4orf14;POLR2B 0.52 4.44 0.37 2e-5 Response to bleomycin (chromatid breaks); TGCT cis rs611744 0.870 rs650925 chr8:109196725 T/C cg21045802 chr8:109455806 TTC35 0.68 6.03 0.48 1.72e-8 Dupuytren's disease; TGCT cis rs8064299 0.574 rs1879455 chr17:72774738 C/G cg25054828 chr17:72772726 NAT9;TMEM104 0.89 9.97 0.67 1.51e-17 Monocyte count; TGCT cis rs6089829 0.962 rs6122350 chr20:61664617 A/G cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs6545883 0.929 rs10190332 chr2:61619267 T/G cg15711740 chr2:61764176 XPO1 0.5 4.46 0.37 1.78e-5 Tuberculosis; TGCT cis rs7666738 0.800 rs13107147 chr4:99028753 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.13 0.42 1.1e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs13191362 0.507 rs2846566 chr6:163059714 G/A cg21926612 chr6:163149169 PACRG;PARK2 -0.58 -5.11 -0.42 1.17e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs13108904 0.539 rs11247997 chr4:1361057 T/C cg13395646 chr4:1353034 KIAA1530 -0.58 -7.97 -0.58 9.03e-13 Obesity-related traits; TGCT cis rs7586879 0.598 rs6545806 chr2:25124348 G/A cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs476633 0.708 rs9888708 chr15:41446030 G/C cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.77 -0.62 1.18e-14 Glomerular filtration rate (creatinine); TGCT cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg09359103 chr1:154839909 KCNN3 -0.65 -12.61 -0.75 5.72e-24 Prostate cancer; TGCT cis rs10540 1.000 rs35996687 chr11:458595 G/A cg03934478 chr11:495069 RNH1 0.34 5.3 0.43 5.01e-7 Body mass index; TGCT cis rs17068510 0.572 rs73503257 chr8:3875692 A/C cg25338036 chr8:3047536 CSMD1 -0.46 -4.88 -0.4 3.19e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs875971 0.540 rs736270 chr7:65428822 T/C cg18876405 chr7:65276391 NA 0.36 5.58 0.45 1.46e-7 Aortic root size; TGCT cis rs7681440 0.904 rs2301135 chr4:90758389 G/C cg26578617 chr4:90757533 SNCA -0.48 -4.95 -0.41 2.35e-6 Dementia with Lewy bodies; TGCT cis rs11711311 0.955 rs7650764 chr3:113414439 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.66 -5.85 -0.46 4.13e-8 IgG glycosylation; TGCT cis rs11578119 0.933 rs4294468 chr1:170433781 G/A cg09767346 chr1:170501363 GORAB -0.72 -5.74 -0.46 6.97e-8 Male-pattern baldness; TGCT cis rs9303401 0.580 rs34076823 chr17:57114497 C/G cg10487724 chr17:56770010 TEX14;RAD51C 0.65 6.06 0.48 1.54e-8 Cognitive test performance; TGCT cis rs950169 0.845 rs4106951 chr15:84833394 C/G cg12863693 chr15:85201151 NMB 0.41 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs7539409 0.915 rs4001467 chr1:84275858 A/T cg10977910 chr1:84465055 TTLL7 -0.94 -5.4 -0.44 3.26e-7 Alzheimer's disease; TGCT cis rs8068544 0.818 rs7209012 chr17:40161323 C/T cg13092355 chr17:39992602 KLHL10;NT5C3L -0.96 -4.47 -0.37 1.72e-5 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs11098499 0.874 rs9995277 chr4:120108603 G/A cg09307838 chr4:120376055 NA 0.5 4.57 0.38 1.14e-5 Corneal astigmatism; TGCT trans rs1814175 0.817 rs4881648 chr11:49812901 A/G cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs7017914 0.905 rs2732104 chr8:71923519 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs16865717 1.000 rs12991466 chr2:7029725 C/A cg20486407 chr2:7037101 RSAD2 -0.38 -5.03 -0.41 1.66e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs4563143 0.704 rs16961809 chr19:29226299 C/T cg04546413 chr19:29218101 NA 0.84 7.96 0.58 9.36e-13 Methadone dose in opioid dependence; TGCT trans rs877282 0.898 rs11253341 chr10:765008 G/C cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs3796352 1.000 rs33999310 chr3:52883332 G/A cg07884673 chr3:53033167 SFMBT1 0.62 5.35 0.43 4.16e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7208859 0.623 rs59029591 chr17:29235746 A/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1395 0.744 rs62130714 chr2:27532870 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 8.01 0.58 7.07e-13 Blood metabolite levels; TGCT cis rs478304 0.651 rs11227281 chr11:65496558 T/C cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.05e-10 Acne (severe); TGCT cis rs9393692 0.905 rs9393693 chr6:26277408 C/A cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT cis rs2204008 0.506 rs11495470 chr12:38026904 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs3824867 0.920 rs4282946 chr11:47456202 G/A cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs3733585 0.699 rs6844787 chr4:9959233 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7659604 0.605 rs67772833 chr4:122723106 G/A cg06713675 chr4:122721982 EXOSC9 -0.62 -8.63 -0.61 2.45e-14 Type 2 diabetes; TGCT cis rs9296092 0.538 rs34222093 chr6:33519584 G/C cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7552404 1.000 rs211718 chr1:76106675 C/T cg10523679 chr1:76189770 ACADM 0.9 9.81 0.66 3.56e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7772486 0.754 rs857881 chr6:145970793 C/A cg23711669 chr6:146136114 FBXO30 -0.92 -10.11 -0.67 6.66e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs7829975 0.688 rs7826654 chr8:8379106 C/T cg06636001 chr8:8085503 FLJ10661 0.77 7.37 0.55 2.12e-11 Mood instability; TGCT cis rs1018836 0.770 rs4324886 chr8:91651943 A/G cg16814680 chr8:91681699 NA -0.93 -10.81 -0.7 1.35e-19 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2075371 0.796 rs7780583 chr7:133960716 C/G cg11752832 chr7:134001865 SLC35B4 0.66 5.5 0.44 2.09e-7 Mean platelet volume; TGCT cis rs12530845 1.000 rs77068811 chr7:135334571 A/G cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs17376456 0.877 rs10078194 chr5:93364310 A/C cg21475434 chr5:93447410 FAM172A 0.6 4.73 0.39 6.08e-6 Diabetic retinopathy; TGCT cis rs45430 1.000 rs408825 chr21:42743496 A/G cg22778903 chr21:42741698 MX2 -0.32 -5.37 -0.43 3.67e-7 Melanoma; TGCT cis rs185694 0.947 rs169331 chr13:30878695 G/T cg07600127 chr13:30881527 KATNAL1 -0.88 -6.7 -0.52 6.43e-10 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs2795502 0.882 rs2744091 chr10:43339441 A/G cg20628663 chr10:43360327 NA -0.42 -6.12 -0.48 1.12e-8 Blood protein levels; TGCT cis rs1577917 0.958 rs12190603 chr6:86475718 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.22 -0.42 7.42e-7 Response to antipsychotic treatment; TGCT cis rs7914558 0.966 rs1591915 chr10:104646849 C/T cg04362960 chr10:104952993 NT5C2 0.58 5.16 0.42 9.65e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7647973 0.961 rs7626076 chr3:49298139 G/A cg07636037 chr3:49044803 WDR6 0.7 5.64 0.45 1.11e-7 Menarche (age at onset); TGCT cis rs1568889 0.838 rs7131379 chr11:28085789 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.35 0.71 6.62e-21 Bipolar disorder; TGCT cis rs73110464 0.609 rs4919752 chr12:53359229 G/C cg16329197 chr12:53359506 NA -0.57 -7.96 -0.58 9.34e-13 Cancer (pleiotropy); TGCT cis rs986417 0.711 rs761556 chr14:61061034 T/G cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs4972806 0.849 rs2857535 chr2:177036211 G/A cg14324370 chr2:177042789 NA 0.74 6.8 0.52 3.87e-10 IgG glycosylation; TGCT cis rs13102973 0.564 rs4418034 chr4:135886650 T/A cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs55692411 0.517 rs62262106 chr3:49991427 A/G cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.547 rs246054 chr5:140326159 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs62244186 0.659 rs9855433 chr3:44468065 C/A cg21672276 chr3:44754072 ZNF502 -0.43 -4.84 -0.4 3.81e-6 Depressive symptoms; TGCT cis rs7523273 0.606 rs2796266 chr1:207922945 C/T cg22525895 chr1:207977042 MIR29B2 -0.52 -8.36 -0.6 1.09e-13 Schizophrenia; TGCT cis rs736801 0.891 rs11242115 chr5:131826413 G/C cg02551604 chr5:131831745 NA 0.57 4.71 0.39 6.64e-6 Breast cancer;Mosquito bite size; TGCT cis rs6570726 0.791 rs425999 chr6:145819370 C/A cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6867032 0.958 rs4975798 chr5:2015580 G/A cg26168224 chr5:2018326 NA 0.43 7.82 0.57 2e-12 Gut microbiome composition (winter); TGCT cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg10802521 chr3:52805072 NEK4 -0.73 -8.94 -0.63 4.43e-15 Bipolar disorder; TGCT cis rs7264396 0.790 rs3787168 chr20:34233278 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs10466239 0.730 rs2245413 chr10:43850568 C/T cg08951903 chr10:44070173 ZNF239 0.8 4.79 0.4 4.67e-6 Telomere length; TGCT cis rs9357506 1.000 rs9395174 chr6:46313100 A/C cg21115430 chr6:46460003 NA -0.23 -4.62 -0.38 9.28e-6 Body mass index; TGCT cis rs6835098 0.520 rs2127896 chr4:174211285 G/A cg08422745 chr4:174089978 GALNT7 -0.53 -4.61 -0.38 9.8200000000000008e-06 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs9393777 0.513 rs9393741 chr6:26654189 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs2299587 0.662 rs7816769 chr8:17768548 G/T cg01800426 chr8:17659068 MTUS1 0.62 5.31 0.43 5e-7 Economic and political preferences; TGCT cis rs11644362 1.000 rs3843707 chr16:12996788 G/A cg06890432 chr16:12997467 SHISA9 -0.61 -6.49 -0.5 1.85e-9 Positive affect;Subjective well-being; TGCT cis rs5769765 0.671 rs138833 chr22:50178917 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.93 -8.67 -0.61 2.04e-14 Schizophrenia; TGCT cis rs9479482 1.000 rs9479481 chr6:150357944 A/G cg03788504 chr6:150331562 NA -0.24 -4.58 -0.38 1.12e-5 Alopecia areata; TGCT cis rs801193 0.967 rs1110414 chr7:66205582 A/G cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.97e-7 Aortic root size; TGCT cis rs7000551 0.725 rs2249102 chr8:22400193 C/G cg12081754 chr8:22256438 SLC39A14 0.28 4.52 0.38 1.4e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6088590 0.603 rs6579186 chr20:33282198 G/C cg06115741 chr20:33292138 TP53INP2 0.56 4.7 0.39 6.83e-6 Coronary artery disease; TGCT cis rs34014631 0.786 rs74910253 chr10:103658324 T/C cg22630918 chr10:102748988 C10orf2 0.42 4.82 0.4 4.15e-6 Coronary artery calcification; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg23131131 chr22:24373011 LOC391322 -0.52 -4.51 -0.38 1.51e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9527 0.641 rs10786732 chr10:104762535 T/C cg04362960 chr10:104952993 NT5C2 0.68 5.7 0.46 8.14e-8 Arsenic metabolism; TGCT cis rs7829975 0.777 rs486781 chr8:8639740 A/G cg15556689 chr8:8085844 FLJ10661 -0.71 -6.23 -0.49 6.8e-9 Mood instability; TGCT cis rs6089584 0.888 rs2386555 chr20:60612373 C/T cg13770153 chr20:60521292 NA -0.54 -6.99 -0.53 1.51e-10 Body mass index; TGCT cis rs2067615 0.579 rs4964486 chr12:107140790 A/G cg15890332 chr12:107067104 RFX4 0.3 5.93 0.47 2.85e-8 Heart rate; TGCT cis rs2688608 0.588 rs10128205 chr10:75469648 C/G cg23231163 chr10:75533350 FUT11 -0.28 -4.58 -0.38 1.12e-5 Inflammatory bowel disease; TGCT cis rs875971 0.522 rs781144 chr7:65440344 C/G cg18876405 chr7:65276391 NA 0.41 6.53 0.51 1.55e-9 Aortic root size; TGCT cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg20203395 chr5:56204925 C5orf35 -0.56 -4.8 -0.4 4.39e-6 Initial pursuit acceleration; TGCT cis rs7223966 0.921 rs3020612 chr17:61960878 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.68 5.32 0.43 4.68e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs367615 0.660 rs10061221 chr5:108839038 C/T cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs42648 0.870 rs7783199 chr7:89999305 G/A cg25739043 chr7:89950458 NA 0.65 6.22 0.49 6.96e-9 Homocysteine levels; TGCT cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.09 -0.42 1.29e-6 Electroencephalogram traits; TGCT cis rs10791097 1.000 rs10791098 chr11:130718711 T/G cg12179176 chr11:130786555 SNX19 0.65 6.88 0.53 2.57e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs12976411 0.558 rs61027832 chr19:32972530 C/A cg09385032 chr19:32252709 NA -0.37 -4.45 -0.37 1.92e-5 Coronary artery disease; TGCT cis rs7246657 0.943 rs7252346 chr19:37914682 G/A cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs17221829 0.673 rs4753228 chr11:89369157 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg21724239 chr8:58056113 NA 0.48 5.17 0.42 9.18e-7 Developmental language disorder (linguistic errors); TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg24503407 chr1:205819492 PM20D1 0.67 10.76 0.69 1.83e-19 Menarche (age at onset); TGCT cis rs2455799 0.613 rs11713820 chr3:15866590 A/G cg16303742 chr3:15540471 COLQ 0.25 4.74 0.39 5.65e-6 Mean platelet volume; TGCT cis rs1577917 0.958 rs12213331 chr6:86504797 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.23 -0.43 7.01e-7 Response to antipsychotic treatment; TGCT cis rs1018836 0.923 rs756569 chr8:91610957 G/A cg16814680 chr8:91681699 NA -0.9 -9.66 -0.66 8.52e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2932538 0.961 rs4839257 chr1:113219388 A/T cg22162597 chr1:113214053 CAPZA1 -0.26 -5.52 -0.44 1.86e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1577917 0.958 rs12198061 chr6:86550985 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs13256369 1.000 rs7843488 chr8:8576217 C/T cg18904891 chr8:8559673 CLDN23 0.63 5.84 0.46 4.38e-8 Obesity-related traits; TGCT cis rs9527 0.590 rs10883839 chr10:104920341 A/G cg04362960 chr10:104952993 NT5C2 0.69 5.75 0.46 6.43e-8 Arsenic metabolism; TGCT cis rs1218582 0.772 rs2061690 chr1:154919080 C/T cg24250549 chr1:154909240 PMVK 0.6 6.04 0.48 1.67e-8 Prostate cancer; TGCT cis rs875971 0.862 rs28470208 chr7:65584700 A/G cg11764359 chr7:65958608 NA -0.53 -4.74 -0.39 5.87e-6 Aortic root size; TGCT cis rs2832077 0.506 rs2832085 chr21:30155258 G/T cg24692254 chr21:30365293 RNF160 -0.59 -5.18 -0.42 8.61e-7 Cognitive test performance; TGCT cis rs10256972 0.521 rs10280960 chr7:1103697 A/G cg18402987 chr7:1209562 NA 0.39 4.48 0.37 1.67e-5 Longevity;Endometriosis; TGCT cis rs8017423 0.967 rs7150093 chr14:90724661 C/T cg04374321 chr14:90722782 PSMC1 -0.76 -7.69 -0.57 3.88e-12 Mortality in heart failure; TGCT cis rs2228479 0.850 rs45524643 chr16:89815824 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs6430585 0.528 rs12464050 chr2:136663110 G/T cg07169764 chr2:136633963 MCM6 1.25 12.4 0.74 1.85e-23 Corneal structure; TGCT cis rs1451375 1.000 rs6949897 chr7:50621920 C/T cg18232548 chr7:50535776 DDC 0.43 6.8 0.52 3.98e-10 Malaria; TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs9733 0.526 rs11204698 chr1:150659545 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT trans rs608114 0.793 rs472816 chr6:96380745 G/C cg04008557 chr11:2826328 KCNQ1 -0.65 -6.82 -0.52 3.51e-10 Response to abacavir-containing treatment in HIV-1 infection (virologic failure);Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs1215050 0.791 rs4699318 chr4:98664370 T/G cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2404602 0.692 rs7174673 chr15:77071998 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg11003573 chr3:44754125 ZNF502 -0.47 -5.5 -0.44 2.08e-7 Depressive symptoms; TGCT cis rs3858526 0.635 rs2045046 chr11:5875867 A/C cg05234568 chr11:5960015 NA -0.49 -4.69 -0.39 7.16e-6 DNA methylation (variation); TGCT cis rs17401966 0.898 rs12757288 chr1:10323921 T/C cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs981844 0.775 rs17371545 chr4:154763980 A/G cg14289246 chr4:154710475 SFRP2 -0.96 -7.75 -0.57 2.85e-12 Response to statins (LDL cholesterol change); TGCT trans rs7618501 0.521 rs952594 chr3:49908023 G/A cg21659725 chr3:3221576 CRBN 0.73 8.19 0.59 2.76e-13 Intelligence (multi-trait analysis); TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg22166914 chr1:53195759 ZYG11B 0.39 6.35 0.5 3.71e-9 Monocyte count; TGCT cis rs4727027 0.899 rs6944096 chr7:148870026 A/G cg23583168 chr7:148888333 NA -0.79 -10.43 -0.68 1.14e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2019216 0.500 rs71371082 chr17:21889647 T/C cg22648282 chr17:21454238 C17orf51 -0.56 -5.07 -0.41 1.42e-6 Pelvic organ prolapse; TGCT cis rs7208859 0.623 rs59447372 chr17:29057585 C/T cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs877282 1.000 rs11253369 chr10:773610 C/G cg22713356 chr15:30763199 NA 1.08 9.57 0.65 1.4e-16 Uric acid levels; TGCT cis rs3617 0.572 rs2256332 chr3:52855865 A/G cg11645453 chr3:52864694 ITIH4 -0.28 -5.43 -0.44 2.86e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6570726 0.755 rs451699 chr6:145830594 C/G cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1215050 0.791 rs1727278 chr4:98853576 A/G cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2851682 0.706 rs2072113 chr11:61604967 C/T cg20584555 chr11:61717780 BEST1 -0.34 -4.8 -0.4 4.42e-6 Gestational age at birth (child effect);Trans fatty acid levels; TGCT cis rs8014204 0.869 rs2070599 chr14:75361177 C/G cg06637938 chr14:75390232 RPS6KL1 -0.7 -6.69 -0.52 6.76e-10 Caffeine consumption; TGCT cis rs66561647 0.719 rs7821928 chr8:128939295 G/A cg05480350 chr8:128972681 MIR1205;PVT1 0.21 4.45 0.37 1.87e-5 Hemoglobin concentration; TGCT cis rs9372253 1.000 rs11153232 chr6:110716252 G/T cg13266496 chr6:110720918 DDO 0.46 5.68 0.45 8.89e-8 Platelet distribution width; TGCT cis rs2280018 0.526 rs1510148 chr16:15167379 T/A cg07549590 chr16:15018862 NA -0.31 -4.84 -0.4 3.86e-6 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs55794721 0.509 rs12027135 chr1:25775733 A/T cg10117171 chr1:25599238 RHD -0.32 -5.17 -0.42 9.25e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs854765 0.534 rs7207461 chr17:17949789 T/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs1008375 0.932 rs13109475 chr4:17677565 C/G cg16339924 chr4:17578868 LAP3 -0.59 -4.82 -0.4 4.05e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1056053 0.514 rs3099269 chr6:166572242 T/A cg17219086 chr6:166541254 NA -0.19 -4.51 -0.38 1.51e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7095607 0.777 rs7905579 chr10:69926594 G/T cg18986048 chr10:69913749 MYPN 0.44 5.03 0.41 1.68e-6 Lung function (FVC); TGCT cis rs4389656 0.857 rs274703 chr5:6728372 A/C cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs3741404 0.825 rs11603384 chr11:63949095 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.94 10.77 0.7 1.71e-19 Platelet count; TGCT cis rs1538970 0.816 rs10789464 chr1:45959102 C/T cg05343316 chr1:45956843 TESK2 0.81 6.64 0.51 8.93e-10 Platelet count; TGCT cis rs2637266 0.905 rs4357630 chr10:78382883 T/G cg18941641 chr10:78392320 NA 0.39 4.77 0.39 5.16e-6 Pulmonary function; TGCT cis rs600231 0.665 rs1616810 chr11:65220105 A/G cg21890820 chr11:65308645 LTBP3 0.38 4.68 0.39 7.36e-6 Bone mineral density; TGCT cis rs2227564 0.620 rs7098573 chr10:75580014 G/A cg19442545 chr10:75533431 FUT11 -0.32 -4.66 -0.39 8.03e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg13877915 chr19:58951672 ZNF132 0.83 9.21 0.64 1.03e-15 Uric acid clearance; TGCT cis rs700651 0.856 rs9288280 chr2:198744324 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Intracranial aneurysm; TGCT cis rs7523273 0.512 rs2761435 chr1:207918466 C/G cg22525895 chr1:207977042 MIR29B2 0.45 7.19 0.54 5.4e-11 Schizophrenia; TGCT cis rs72781680 0.898 rs72782138 chr2:24048162 T/C cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs1505368 0.562 rs7569142 chr2:213294557 C/T cg16329650 chr2:213403929 ERBB4 0.67 6.28 0.49 5.25e-9 Symmetrical dimethylarginine levels; TGCT cis rs936229 0.656 rs12898397 chr15:75130093 T/C cg10253484 chr15:75165896 SCAMP2 -0.51 -4.7 -0.39 6.93e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs9467603 1.000 rs9467600 chr6:25792768 C/T cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs7781977 0.960 rs17732497 chr7:50336073 C/A cg01139861 chr7:50343298 IKZF1 0.56 6.04 0.48 1.63e-8 IgG glycosylation; TGCT cis rs4972806 0.849 rs2857541 chr2:177029086 C/T cg14324370 chr2:177042789 NA 0.74 6.89 0.53 2.53e-10 IgG glycosylation; TGCT cis rs12950390 0.853 rs66471233 chr17:45867086 C/T cg24803719 chr17:45855879 NA -0.49 -5.03 -0.41 1.64e-6 IgG glycosylation; TGCT cis rs17761864 0.959 rs16952025 chr17:2116798 C/T cg02171503 chr17:1588363 PRPF8 0.48 4.67 0.39 7.86e-6 Esophageal cancer (squamous cell); TGCT cis rs10464366 0.544 rs953874 chr7:39147916 G/A cg18850127 chr7:39170497 POU6F2 0.32 6.94 0.53 1.97e-10 IgG glycosylation; TGCT cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg11211951 chr8:145729740 GPT -0.22 -4.99 -0.41 1.95e-6 Age at first birth; TGCT trans rs8073060 0.586 rs225264 chr17:33961335 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9393692 0.967 rs6456712 chr6:26302573 A/C cg05868516 chr6:26286170 HIST1H4H 0.62 5.85 0.46 4.17e-8 Educational attainment; TGCT cis rs6484504 0.576 rs2756191 chr11:31135882 A/T cg26647111 chr11:31128758 NA 0.32 4.53 0.38 1.39e-5 Red blood cell count; TGCT cis rs2153535 0.580 rs2184582 chr6:8447793 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs826838 0.934 rs10875647 chr12:38856995 G/A cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs3749237 0.595 rs6784820 chr3:49450864 C/T cg03060546 chr3:49711283 APEH -0.76 -8.82 -0.62 8.61e-15 Resting heart rate; TGCT cis rs9303401 0.659 rs62081315 chr17:56781468 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs6570726 0.526 rs4895674 chr6:145735860 T/G cg23711669 chr6:146136114 FBXO30 -0.53 -4.72 -0.39 6.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg02458000 chr6:26745757 NA 0.51 4.77 0.39 5.08e-6 Intelligence (multi-trait analysis); TGCT cis rs1401999 1.000 rs6804242 chr3:183659463 A/T cg01324343 chr3:183735012 ABCC5 0.82 10.93 0.7 6.83e-20 Anterior chamber depth; TGCT cis rs2243480 1.000 rs34192067 chr7:65887657 C/A cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs9329221 0.905 rs13254263 chr8:10255181 A/G cg21775007 chr8:11205619 TDH -0.53 -4.8 -0.4 4.5e-6 Neuroticism; TGCT cis rs6904897 0.563 rs6569976 chr6:135224753 A/C cg22676075 chr6:135203613 NA 0.64 6.94 0.53 1.95e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7937682 0.883 rs529529 chr11:111461128 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs4689592 0.513 rs3857177 chr4:7066332 G/A cg26116260 chr4:7069785 GRPEL1 1.13 11.1 0.71 2.59e-20 Monocyte percentage of white cells; TGCT cis rs1775715 0.737 rs2151047 chr10:32102110 G/A cg14930904 chr10:32216787 ARHGAP12 0.5 4.85 0.4 3.62e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs4654899 0.931 rs7543140 chr1:21180250 G/A cg01072550 chr1:21505969 NA 0.5 7.97 0.58 9.06e-13 Superior frontal gyrus grey matter volume; TGCT cis rs477895 1.000 rs7947143 chr11:64090422 G/A cg04317338 chr11:64019027 PLCB3 0.71 5.65 0.45 1.05e-7 Mean platelet volume; TGCT cis rs9467711 0.538 rs35934643 chr6:26355094 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12210905 1.000 rs9357034 chr6:27243425 C/G cg08851530 chr6:28072375 NA 1.32 5.78 0.46 5.66e-8 Hip circumference adjusted for BMI; TGCT cis rs10782582 0.593 rs12130832 chr1:76234294 T/C cg03433033 chr1:76189801 ACADM -0.55 -6.1 -0.48 1.25e-8 Daytime sleep phenotypes; TGCT cis rs7246657 0.722 rs2972447 chr19:38129736 C/T cg18154014 chr19:37997991 ZNF793 -0.69 -4.67 -0.39 7.7e-6 Coronary artery calcification; TGCT cis rs1056107 0.931 rs3908939 chr9:114991338 G/C cg02332936 chr9:115140584 NA -0.25 -4.45 -0.37 1.89e-5 Colorectal cancer; TGCT cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg11494091 chr17:61959527 GH2 0.42 7.38 0.55 1.96e-11 Height; TGCT cis rs1215050 0.791 rs165241 chr4:98681112 C/T cg05340658 chr4:99064831 C4orf37 0.43 5.4 0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2180341 0.920 rs7756880 chr6:127683999 A/T cg27446573 chr6:127587934 RNF146 1.21 10.87 0.7 9.57e-20 Breast cancer; TGCT cis rs950027 0.596 rs2467865 chr15:45638307 T/C cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg25767906 chr1:53392781 SCP2 -0.57 -7.05 -0.53 1.12e-10 Monocyte count; TGCT cis rs7208859 0.673 rs9915963 chr17:29019643 C/T cg13385521 chr17:29058706 SUZ12P 0.74 4.65 0.39 8.3e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs908922 0.676 rs4240887 chr1:152530510 C/T cg20991723 chr1:152506922 NA -0.45 -6.05 -0.48 1.6e-8 Hair morphology; TGCT cis rs62244186 0.659 rs9819766 chr3:44520980 G/C cg02073558 chr3:44770973 ZNF501 0.61 5.86 0.47 3.91e-8 Depressive symptoms; TGCT cis rs4665809 0.652 rs6727974 chr2:26524639 A/G cg25036284 chr2:26402008 FAM59B 0.59 4.74 0.39 5.65e-6 Gut microbiome composition (summer); TGCT cis rs72945132 0.825 rs7950280 chr11:70213455 G/T cg00319359 chr11:70116639 PPFIA1 0.99 7.39 0.55 1.94e-11 Coronary artery disease; TGCT cis rs7552404 1.000 rs7524467 chr1:76194054 C/G cg10523679 chr1:76189770 ACADM 0.9 9.67 0.66 7.93e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs73198271 0.960 rs12155530 chr8:8610964 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.79 -0.39 4.72e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs56804039 0.524 rs4840989 chr8:8405746 C/G cg14215082 chr8:9055850 NA -0.45 -4.59 -0.38 1.08e-5 Cervical cancer; TGCT cis rs12220898 0.679 rs4838485 chr10:50484825 T/A cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT trans rs6089829 0.926 rs1060489 chr20:61665921 C/T cg17470723 chr8:74884337 TCEB1 0.74 6.92 0.53 2.19e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1577917 0.958 rs11755642 chr6:86450066 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.48 -0.44 2.28e-7 Response to antipsychotic treatment; TGCT cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs11690935 0.959 rs6754817 chr2:172663394 C/T cg13550731 chr2:172543902 DYNC1I2 -1.16 -12.41 -0.74 1.73e-23 Schizophrenia; TGCT cis rs7208859 0.562 rs11650923 chr17:29008167 G/A cg14008862 chr17:28927542 LRRC37B2 0.84 5.1 0.42 1.22e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg07061783 chr6:25882402 NA 0.45 4.83 0.4 3.93e-6 Blood metabolite levels; TGCT cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg16145915 chr7:1198662 ZFAND2A -0.5 -6.21 -0.49 7.17e-9 Longevity;Endometriosis; TGCT cis rs782590 0.902 rs3762513 chr2:55762957 C/T cg18811423 chr2:55921094 PNPT1 0.67 7.1 0.54 8.56e-11 Metabolic syndrome; TGCT cis rs11588062 0.703 rs11589812 chr1:46858748 C/T cg01431908 chr1:46668882 C1orf190;POMGNT1 0.48 4.77 0.39 5.18e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs208515 0.525 rs10455593 chr6:66691341 C/T cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs17445774 0.857 rs6435043 chr2:200900974 C/G cg23649088 chr2:200775458 C2orf69 0.49 7.36 0.55 2.19e-11 LDL cholesterol to HDL cholesterol ratio; TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg20007245 chr22:24372913 LOC391322 -0.65 -6.44 -0.5 2.34e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg23205692 chr1:25664452 TMEM50A 0.53 5.42 0.44 2.96e-7 Erythrocyte sedimentation rate; TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg16590910 chr6:42928470 GNMT -0.49 -4.52 -0.38 1.41e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9976767 0.637 rs9325635 chr21:43823289 G/A cg23042151 chr21:43824109 UBASH3A -0.23 -5.04 -0.41 1.62e-6 Type 1 diabetes; TGCT cis rs11690935 0.959 rs6759575 chr2:172689068 C/T cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.12 -0.74 8.77e-23 Schizophrenia; TGCT cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg20607798 chr8:58055168 NA 0.59 4.74 0.39 5.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg00024416 chr22:24240387 NA -0.25 -4.7 -0.39 6.69e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11105298 0.891 rs10858889 chr12:89902604 G/A cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs3008870 1.000 rs2755256 chr1:67471692 A/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs1018836 0.847 rs4735225 chr8:91569100 G/C cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs546131 0.928 rs552171 chr11:34830709 G/T cg06937548 chr11:34938143 PDHX;APIP 0.68 6.07 0.48 1.47e-8 Lung disease severity in cystic fibrosis; TGCT cis rs12681287 0.608 rs13273338 chr8:87453361 T/G cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs78487399 0.808 rs13405776 chr2:43739121 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6570726 0.791 rs9322029 chr6:145906683 A/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs875971 0.867 rs1002053 chr7:65798545 G/A cg18876405 chr7:65276391 NA -0.32 -4.93 -0.4 2.63e-6 Aortic root size; TGCT cis rs2486288 0.656 rs6493145 chr15:45573862 G/T cg26924012 chr15:45694286 SPATA5L1 -0.8 -8.41 -0.6 8.03e-14 Glomerular filtration rate; TGCT cis rs9303401 0.659 rs12150536 chr17:56640834 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.18 0.49 8.56e-9 Cognitive test performance; TGCT cis rs4319547 0.695 rs7969429 chr12:122875606 A/G cg08088222 chr12:122070432 ORAI1 0.25 4.49 0.37 1.58e-5 Body mass index; TGCT cis rs7811142 0.830 rs11761426 chr7:99956893 A/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs4319547 0.737 rs10846921 chr12:122943376 G/T cg05707623 chr12:122985044 ZCCHC8 0.59 4.73 0.39 5.99e-6 Body mass index; TGCT cis rs9322193 0.923 rs9479094 chr6:150046219 C/T cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs854765 0.647 rs741782 chr17:18019712 T/C cg04398451 chr17:18023971 MYO15A -0.39 -6.75 -0.52 5e-10 Total body bone mineral density; TGCT cis rs12049351 0.667 rs34382491 chr1:229620630 G/A cg12130225 chr1:229698885 NA 0.4 4.71 0.39 6.57e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs2296887 0.841 rs11191252 chr10:104060060 G/C cg26089160 chr10:104170217 PSD -0.61 -5.66 -0.45 1.01e-7 Parkinson's disease; TGCT cis rs765787 0.530 rs12439643 chr15:45529767 A/G cg24006582 chr15:45444508 DUOX1 0.24 5.37 0.43 3.8e-7 Uric acid levels; TGCT cis rs12497850 0.931 rs4974085 chr3:48924900 C/T cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs752092 0.894 rs8043243 chr15:101771453 C/T cg19997662 chr15:101784653 CHSY1 -0.27 -4.85 -0.4 3.7e-6 Corneal structure; TGCT cis rs17152411 1.000 rs7083298 chr10:126590691 T/C cg07906193 chr10:126599966 NA 0.42 5.16 0.42 9.55e-7 Height; TGCT cis rs7027203 0.797 rs3996254 chr9:96591239 A/G cg14598338 chr9:96623480 NA -0.61 -9.54 -0.65 1.68e-16 DNA methylation (variation); TGCT trans rs1814175 0.781 rs12286395 chr11:49954062 C/G cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs4665809 1.000 rs12469163 chr2:26283587 T/C cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs6951245 0.554 rs58210047 chr7:1149381 G/A cg03188948 chr7:1209495 NA 0.5 5.27 0.43 5.87e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs554111 0.891 rs646786 chr1:21054726 A/G cg08890418 chr1:21044141 KIF17 0.56 6.04 0.48 1.69e-8 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs769267 0.965 rs12460764 chr19:19431963 G/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs2239547 0.618 rs4687663 chr3:52870618 T/A cg11645453 chr3:52864694 ITIH4 0.35 5.76 0.46 6.35e-8 Schizophrenia; TGCT cis rs6964587 0.967 rs7786031 chr7:91649001 T/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs2721195 0.781 rs10110962 chr8:145780323 C/T cg11211951 chr8:145729740 GPT 0.24 5.64 0.45 1.1e-7 Age at first birth; TGCT cis rs2228479 0.717 rs34027607 chr16:89808939 T/C cg04287289 chr16:89883240 FANCA 0.74 4.44 0.37 1.99e-5 Skin colour saturation; TGCT cis rs9910055 1.000 rs9895423 chr17:42285740 T/C cg19774624 chr17:42201019 HDAC5 -0.85 -8.07 -0.59 5.18e-13 Total body bone mineral density; TGCT cis rs7647973 0.961 rs7626076 chr3:49298139 G/A cg05785598 chr3:49045655 WDR6 0.39 4.58 0.38 1.13e-5 Menarche (age at onset); TGCT cis rs4654899 0.931 rs4654727 chr1:21214735 C/T cg01072550 chr1:21505969 NA 0.5 7.95 0.58 9.89e-13 Superior frontal gyrus grey matter volume; TGCT cis rs514406 0.505 rs856721 chr1:53162156 C/A cg08859206 chr1:53392774 SCP2 -0.34 -4.74 -0.39 5.77e-6 Monocyte count; TGCT cis rs259282 0.605 rs60968670 chr19:33108982 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.52 4.78 0.39 4.94e-6 Schizophrenia; TGCT cis rs295140 0.586 rs4673904 chr2:201163454 A/T cg04283868 chr2:201171347 SPATS2L 0.6 5.93 0.47 2.75e-8 QT interval; TGCT cis rs6121246 0.529 rs6058152 chr20:30178107 G/A cg18721089 chr20:30220636 NA -0.63 -6.86 -0.52 2.95e-10 Mean corpuscular hemoglobin; TGCT cis rs9902453 0.967 rs12602258 chr17:28317657 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 6.61 0.51 1.02e-9 Coffee consumption (cups per day); TGCT cis rs911555 0.755 rs12435516 chr14:103954404 T/C cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs9457247 0.534 rs9347170 chr6:167405187 C/T cg23791538 chr6:167370224 RNASET2 0.61 6.02 0.48 1.85e-8 Crohn's disease; TGCT cis rs7772486 0.902 rs1331643 chr6:146398873 T/A cg05347473 chr6:146136440 FBXO30 0.55 5.27 0.43 5.86e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs12488721 1 rs12488721 chr3:135992645 T/C cg12473912 chr3:136751656 NA 0.34 4.85 0.4 3.7e-6 Neuroticism; TGCT cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg07061783 chr6:25882402 NA -0.62 -6.15 -0.48 9.71e-9 Intelligence (multi-trait analysis); TGCT cis rs7584330 0.554 rs76605518 chr2:238425992 G/A cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs7772486 0.875 rs2814876 chr6:146304030 C/T cg23711669 chr6:146136114 FBXO30 0.88 9.48 0.65 2.31e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs754133 0.535 rs7134677 chr12:54441498 C/T cg16264616 chr12:54390824 NA 0.4 5.56 0.45 1.57e-7 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs6570726 0.905 rs396492 chr6:145816180 C/G cg23711669 chr6:146136114 FBXO30 0.7 6.6 0.51 1.09e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6582630 0.502 rs11181214 chr12:38298313 C/A cg26384229 chr12:38710491 ALG10B 0.8 7.08 0.54 9.28e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs12579753 0.956 rs7959951 chr12:82231132 T/C cg07988820 chr12:82153109 PPFIA2 -0.58 -6.25 -0.49 6.15e-9 Resting heart rate; TGCT cis rs4722166 0.564 rs1800797 chr7:22766221 A/G cg13104385 chr7:22767384 IL6 0.2 4.65 0.39 8.45e-6 Lung cancer; TGCT cis rs2361718 0.900 rs8081698 chr17:78104212 G/A cg09238746 chr17:78121135 EIF4A3 -0.55 -4.68 -0.39 7.5e-6 Yeast infection; TGCT cis rs911555 0.755 rs2765046 chr14:103980968 G/A cg12935359 chr14:103987150 CKB 0.36 4.89 0.4 3.03e-6 Intelligence (multi-trait analysis); TGCT cis rs7209700 0.662 rs11656865 chr17:45346489 A/G cg21624342 chr17:45890973 OSBPL7 0.18 4.58 0.38 1.12e-5 IgG glycosylation; TGCT cis rs7511006 0.893 rs5771104 chr22:50651839 C/T cg19026356 chr22:50624276 TRABD -0.49 -4.52 -0.38 1.45e-5 Obesity-related traits; TGCT cis rs2288884 0.747 rs11668885 chr19:52591101 C/T cg13540795 chr19:52551618 ZNF432 -0.65 -5.42 -0.44 2.97e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs4631830 0.900 rs9787697 chr10:51533376 C/T cg10326726 chr10:51549505 MSMB -0.27 -5.46 -0.44 2.54e-7 Prostate-specific antigen levels; TGCT cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2921073 0.509 rs2976931 chr8:8257317 C/A cg06636001 chr8:8085503 FLJ10661 0.69 6.02 0.48 1.81e-8 Parkinson's disease; TGCT cis rs2404602 0.716 rs12907805 chr15:76690606 C/T cg22467129 chr15:76604101 ETFA -0.59 -7.13 -0.54 7.47e-11 Blood metabolite levels; TGCT cis rs28595532 0.920 rs116106661 chr4:119749794 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs829880 0.570 rs844205 chr12:98846053 A/G cg25150519 chr12:98850993 NA 0.65 5.77 0.46 5.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.554 rs79020383 chr2:238425834 G/A cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs2594989 0.943 rs346070 chr3:11303874 T/C cg00170343 chr3:11313890 ATG7 0.68 4.9 0.4 2.98e-6 Circulating chemerin levels; TGCT cis rs13256369 1.000 rs13256369 chr8:8577379 T/C cg06671706 chr8:8559999 CLDN23 0.35 4.7 0.39 6.89e-6 Obesity-related traits; TGCT cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg08048268 chr3:133502702 NA -0.7 -11.34 -0.71 6.72e-21 Iron status biomarkers; TGCT cis rs4638749 1.000 rs1466213 chr2:108856607 G/A cg06795125 chr2:108905320 SULT1C2 -0.39 -4.81 -0.4 4.26e-6 Blood pressure; TGCT cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.51 -4.79 -0.4 4.64e-6 Colorectal cancer; TGCT cis rs11252926 0.574 rs4881254 chr10:453567 C/T cg20256804 chr10:444983 DIP2C -0.21 -4.45 -0.37 1.88e-5 Psychosis in Alzheimer's disease; TGCT cis rs2153535 0.542 rs4440510 chr6:8471818 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.07 0.41 1.43e-6 Motion sickness; TGCT cis rs875971 0.522 rs2949690 chr7:65483242 C/T cg00343986 chr7:65444356 GUSB -0.26 -5.95 -0.47 2.5e-8 Aortic root size; TGCT cis rs1998418 0.611 rs12414136 chr10:126548533 C/G cg03585084 chr10:126284563 LHPP -0.28 -4.76 -0.39 5.39e-6 Mean platelet volume; TGCT cis rs4746818 0.818 rs10823302 chr10:70895418 G/T cg04149295 chr10:70884716 VPS26A 0.79 5.4 0.44 3.22e-7 Left atrial antero-posterior diameter; TGCT cis rs4819052 0.851 rs2255766 chr21:46683777 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9916302 0.904 rs588193 chr17:37440439 A/C cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs739401 0.595 rs6578305 chr11:3001120 C/T cg05729581 chr11:3078854 CARS -0.55 -4.93 -0.41 2.54e-6 Longevity; TGCT cis rs938554 0.513 rs3775948 chr4:9995182 G/C cg00071950 chr4:10020882 SLC2A9 0.57 4.77 0.39 5.07e-6 Blood metabolite levels; TGCT cis rs6089584 0.546 rs6061980 chr20:60618877 G/A cg13770153 chr20:60521292 NA -0.41 -5.09 -0.42 1.28e-6 Body mass index; TGCT cis rs67133203 0.659 rs407135 chr12:51411353 G/T cg01517968 chr12:52348879 ACVR1B -0.35 -4.52 -0.38 1.44e-5 Urinary tract infection frequency; TGCT cis rs6867032 0.570 rs13166888 chr5:1982966 G/T cg05184729 chr5:1962311 NA 0.27 4.51 0.38 1.47e-5 Gut microbiome composition (winter); TGCT cis rs1552244 0.554 rs3774207 chr3:9985656 C/T cg00149659 chr3:10157352 C3orf10 0.61 4.44 0.37 1.97e-5 Alzheimer's disease; TGCT cis rs909674 0.541 rs5757655 chr22:39797178 C/G cg02038168 chr22:39784481 NA 0.78 6.82 0.52 3.63e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs11105298 0.891 rs4842664 chr12:89938030 G/A cg00757033 chr12:89920650 WDR51B 0.31 4.66 0.39 7.89e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg17554472 chr22:41940697 POLR3H -0.43 -4.47 -0.37 1.76e-5 Vitiligo; TGCT cis rs2050392 0.624 rs303436 chr10:30731893 G/T cg18806716 chr10:30721971 MAP3K8 -0.72 -10.07 -0.67 8.65e-18 Inflammatory bowel disease; TGCT cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.71 7.56 0.56 7.98e-12 Blood metabolite levels; TGCT cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg04267008 chr7:1944627 MAD1L1 -0.42 -5.4 -0.44 3.3e-7 Bipolar disorder and schizophrenia; TGCT cis rs2228479 0.850 rs11076619 chr16:89831243 C/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7412746 0.611 rs11204747 chr1:150927152 A/G cg09365446 chr1:150670422 GOLPH3L -0.34 -4.72 -0.39 6.35e-6 Melanoma; TGCT cis rs10501293 0.746 rs7131154 chr11:43001206 A/G cg03447554 chr11:43094025 NA 0.42 5.95 0.47 2.58e-8 Cognitive performance; TGCT cis rs34467563 0.934 rs12542955 chr8:97410618 G/T cg15747595 chr8:98289880 TSPYL5 -0.43 -4.76 -0.39 5.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9372498 0.536 rs62422235 chr6:118971913 G/A cg07617317 chr6:118971624 C6orf204 0.47 4.81 0.4 4.3e-6 Diastolic blood pressure; TGCT cis rs6089829 0.889 rs6090206 chr20:61668363 G/A cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg25703541 chr22:24373054 LOC391322 -0.8 -6.48 -0.5 1.92e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs17376456 0.825 rs34967135 chr5:93221785 G/A cg25358565 chr5:93447407 FAM172A 1.01 8.13 0.59 3.77e-13 Diabetic retinopathy; TGCT trans rs6089829 0.962 rs6011548 chr20:61666063 C/T cg13615516 chr5:77269221 NA 0.69 8.57 0.61 3.51e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs617219 0.737 rs6453431 chr5:78493873 G/C cg23987322 chr5:78407566 BHMT 0.36 4.84 0.4 3.75e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7666738 0.570 rs11097612 chr4:99079772 T/C cg17366294 chr4:99064904 C4orf37 0.57 5.34 0.43 4.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1670533 1.000 rs641987 chr4:1077542 C/T cg27284194 chr4:1044797 NA 0.68 5.84 0.46 4.28e-8 Recombination rate (females); TGCT cis rs992157 0.735 rs12990082 chr2:219102332 C/T cg00012203 chr2:219082015 ARPC2 0.81 9.96 0.67 1.57e-17 Colorectal cancer; TGCT cis rs7945705 0.692 rs2742470 chr11:9004002 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -4.95 -0.41 2.38e-6 Hemoglobin concentration; TGCT cis rs2228479 0.717 rs11649210 chr16:89807233 C/G cg06558623 chr16:89946397 TCF25 0.41 4.46 0.37 1.83e-5 Skin colour saturation; TGCT cis rs7178572 0.889 rs7171448 chr15:77832316 C/G cg22256960 chr15:77711686 NA -0.97 -11.25 -0.71 1.13e-20 Type 2 diabetes; TGCT cis rs6426558 0.537 rs1320494 chr1:227241300 A/T cg10327440 chr1:227177885 CDC42BPA 0.61 7.41 0.55 1.72e-11 Neutrophil percentage of white cells; TGCT cis rs9341808 0.690 rs2322634 chr6:80874014 A/C cg08355045 chr6:80787529 NA 0.32 5.64 0.45 1.11e-7 Sitting height ratio; TGCT cis rs6558530 1.000 rs6558530 chr8:1706207 A/G cg09410841 chr8:1729607 CLN8 0.87 9.5 0.65 2e-16 Systolic blood pressure; TGCT cis rs12220238 0.722 rs7894466 chr10:76401365 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.59 4.54 0.38 1.29e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs6089584 0.853 rs1746280 chr20:60577821 C/G cg13770153 chr20:60521292 NA -0.48 -6.31 -0.49 4.51e-9 Body mass index; TGCT cis rs752010 0.523 rs10890158 chr1:42117985 C/T cg06885757 chr1:42089581 HIVEP3 0.28 4.96 0.41 2.27e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs9611565 0.559 rs8139993 chr22:41995335 T/C cg06634786 chr22:41940651 POLR3H -0.83 -7.66 -0.57 4.6e-12 Vitiligo; TGCT cis rs10276381 1.000 rs10281214 chr7:28185544 G/C cg23620719 chr7:28220237 JAZF1 1.01 5.82 0.46 4.75e-8 Crohn's disease; TGCT cis rs10256972 0.521 rs871019 chr7:1105230 A/G cg03188948 chr7:1209495 NA 0.47 5.81 0.46 4.9e-8 Longevity;Endometriosis; TGCT cis rs5758659 0.714 rs2413668 chr22:42505841 G/A cg15557168 chr22:42548783 NA 0.18 4.63 0.38 9.14e-6 Cognitive function; TGCT cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.52 5.49 0.44 2.14e-7 Menopause (age at onset); TGCT cis rs9899728 0.539 rs12938889 chr17:73039929 A/C cg27626185 chr17:73056755 KCTD2 0.91 7.86 0.58 1.63e-12 Alzheimer's disease or small vessel stroke; TGCT cis rs6547741 1.000 rs6749052 chr2:27772879 A/T cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs950169 0.881 rs34591918 chr15:84950833 C/T cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs2456568 0.900 rs2456559 chr11:93668858 A/T cg16099599 chr11:93583650 C11orf90 -0.39 -4.63 -0.38 9.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4455778 0.757 rs9791574 chr7:49010732 A/C cg26309511 chr7:48887640 NA -0.48 -5.89 -0.47 3.42e-8 Lung cancer in never smokers; TGCT cis rs7772486 0.790 rs1854900 chr6:146331382 G/A cg05347473 chr6:146136440 FBXO30 0.55 5.27 0.43 5.84e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2832191 1.000 rs9984793 chr21:30486471 T/C cg24692254 chr21:30365293 RNF160 -0.83 -8.71 -0.62 1.58e-14 Dental caries; TGCT cis rs6908034 0.660 rs7750716 chr6:19804839 C/T cg02682789 chr6:19804855 NA 0.92 5.24 0.43 6.7e-7 Endometriosis;Deep ovarian and/or rectovaginal disease with dense adhesions; TGCT cis rs7178572 0.962 rs1022172 chr15:77793359 A/G cg15453836 chr15:77711506 NA -0.39 -4.51 -0.38 1.46e-5 Type 2 diabetes; TGCT cis rs9534288 0.830 rs1126363 chr13:46633459 C/T cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs11098499 0.754 rs10006259 chr4:120242145 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs13242816 1.000 rs12669740 chr7:116138576 T/C cg16553024 chr7:116138462 CAV2 -0.44 -5.34 -0.43 4.29e-7 P wave duration; TGCT cis rs1865760 0.622 rs9968910 chr6:26072095 A/C cg17691542 chr6:26056736 HIST1H1C 0.7 5.48 0.44 2.32e-7 Height; TGCT cis rs887829 0.569 rs4148326 chr2:234673462 T/C cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.49 -0.37 1.63e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs7830933 0.780 rs1561105 chr8:23610799 T/G cg04349084 chr8:23602677 NA 0.24 4.72 0.39 6.22e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs9911578 0.835 rs9303398 chr17:56484257 T/C cg05425664 chr17:57184151 TRIM37 0.61 5.76 0.46 6.33e-8 Intelligence (multi-trait analysis); TGCT cis rs10489525 0.599 rs2335724 chr1:115608444 T/C cg12756093 chr1:115239321 AMPD1 -0.41 -5.55 -0.45 1.65e-7 Autism; TGCT cis rs10858047 0.831 rs11102826 chr1:115181607 T/A cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs6951245 1.000 rs74347384 chr7:1072440 G/A cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.830 rs13149404 chr4:99070236 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6121246 0.529 rs6060134 chr20:30176794 A/G cg13852791 chr20:30311386 BCL2L1 0.69 4.53 0.38 1.36e-5 Mean corpuscular hemoglobin; TGCT cis rs8177253 0.514 rs6790668 chr3:133442481 T/A cg16262614 chr3:133464971 TF 0.33 4.46 0.37 1.82e-5 Iron status biomarkers; TGCT cis rs7246657 0.722 rs10404031 chr19:38035954 A/G cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs3782455 0.793 rs2290799 chr12:114404208 G/A cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10791097 0.690 rs12284540 chr11:130729772 T/C cg12179176 chr11:130786555 SNX19 0.73 8.64 0.61 2.3e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.78 5.65 0.45 1.03e-7 Platelet count; TGCT cis rs4767364 0.614 rs610303 chr12:112145100 C/A cg10833066 chr12:111807467 FAM109A 0.31 5.13 0.42 1.09e-6 Oral cavity and pharyngeal cancer; TGCT trans rs2727020 0.729 rs685789 chr11:49241228 G/A cg15704280 chr7:45808275 SEPT13 0.7 7.47 0.56 1.26e-11 Coronary artery disease; TGCT cis rs3806843 0.549 rs246012 chr5:140336277 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs10832169 0.933 rs2049724 chr11:14078151 C/T cg04547675 chr11:13986162 SPON1 -0.51 -4.55 -0.38 1.24e-5 Blood protein levels; TGCT cis rs8020441 0.541 rs113935613 chr14:51163847 C/T cg04730355 chr14:51134070 SAV1 1.06 8.42 0.6 7.8e-14 Cognitive performance; TGCT cis rs4819052 0.851 rs4819038 chr21:46659393 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs250677 0.687 rs1422581 chr5:148437386 C/T cg23229984 chr5:148520753 ABLIM3 -0.2 -4.65 -0.39 8.53e-6 Breast cancer; TGCT cis rs2797160 0.967 rs6910786 chr6:126017141 A/T cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs986417 0.901 rs11627533 chr14:61037801 C/T cg18240143 chr14:60952599 C14orf39 0.96 4.59 0.38 1.05e-5 Gut microbiota (bacterial taxa); TGCT trans rs2727020 0.595 rs7924311 chr11:49507573 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.03 -0.53 1.25e-10 Coronary artery disease; TGCT cis rs11190604 1.000 rs2495753 chr10:102325640 C/T cg23241863 chr10:102295624 HIF1AN 0.67 4.9 0.4 2.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs769267 0.965 rs1010207 chr19:19416045 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs2243480 0.711 rs2420172 chr7:65635341 T/C cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs4665630 0.614 rs12623694 chr2:23887153 A/G cg08063864 chr2:24346004 PFN4;LOC375190 -0.95 -4.78 -0.39 4.79e-6 Hypertension; TGCT cis rs10504229 0.817 rs55949560 chr8:58167603 T/C cg22535103 chr8:58192502 C8orf71 -0.35 -4.61 -0.38 1e-5 Developmental language disorder (linguistic errors); TGCT cis rs6714710 0.603 rs953320 chr2:98606770 T/C cg26665480 chr2:98280029 ACTR1B 0.66 6.26 0.49 5.84e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs3796352 1.000 rs34340609 chr3:53077276 A/G cg07884673 chr3:53033167 SFMBT1 0.56 5.96 0.47 2.43e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8180040 0.966 rs6787422 chr3:47418509 G/T cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs3749237 0.595 rs4855861 chr3:49525962 G/T cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs8082590 1 rs8082590 chr17:17958402 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.8 -8.45 -0.6 6.61e-14 Schizophrenia; TGCT cis rs17376456 0.690 rs6892055 chr5:93113023 A/T cg21475434 chr5:93447410 FAM172A 0.62 4.86 0.4 3.46e-6 Diabetic retinopathy; TGCT cis rs7000551 0.751 rs2449341 chr8:22390937 C/A cg12081754 chr8:22256438 SLC39A14 0.28 4.54 0.38 1.29e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2836974 0.681 rs8128827 chr21:40710547 C/T cg11890956 chr21:40555474 PSMG1 1.02 9.9 0.66 2.16e-17 Cognitive function; TGCT cis rs9916302 0.904 rs8066704 chr17:37477218 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs9467711 0.606 rs2393667 chr6:26421345 T/C cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9291683 0.679 rs2241483 chr4:10099831 A/G cg00071950 chr4:10020882 SLC2A9 -0.46 -4.9 -0.4 2.97e-6 Bone mineral density; TGCT cis rs6671200 0.607 rs10874908 chr1:95704151 C/G cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs12479064 0.724 rs4851203 chr2:99986932 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.77 -6.7 -0.52 6.68e-10 Chronic sinus infection; TGCT cis rs13256369 0.774 rs11777719 chr8:8581038 A/G cg18904891 chr8:8559673 CLDN23 0.58 5.09 0.42 1.27e-6 Obesity-related traits; TGCT cis rs4654899 0.680 rs2305463 chr1:21180181 C/T cg01072550 chr1:21505969 NA 0.54 8.72 0.62 1.54e-14 Superior frontal gyrus grey matter volume; TGCT cis rs11671005 0.735 rs12986387 chr19:58927215 C/T cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT cis rs904251 0.965 rs62406516 chr6:37439364 C/T cg25019722 chr6:37503610 NA -0.47 -6.26 -0.49 5.69e-9 Cognitive performance; TGCT cis rs988712 0.576 rs6265 chr11:27679916 C/T cg10635145 chr11:27742435 BDNF -0.45 -5.97 -0.47 2.31e-8 Obesity; TGCT cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg11494091 chr17:61959527 GH2 0.43 7.51 0.56 9.88e-12 Height; TGCT cis rs2836974 0.966 rs7283420 chr21:40666865 T/C cg06238570 chr21:40685208 BRWD1 0.58 5.22 0.42 7.22e-7 Cognitive function; TGCT cis rs736408 1.000 rs4687552 chr3:52838402 T/C cg07507251 chr3:52567010 NT5DC2 0.49 6.4 0.5 2.96e-9 Bipolar disorder; TGCT cis rs1552244 0.572 rs2054478 chr3:10172211 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.93 5.43 0.44 2.89e-7 Alzheimer's disease; TGCT cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg18305652 chr10:134549665 INPP5A 0.33 5.54 0.45 1.74e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs13191362 1.000 rs34443622 chr6:163208214 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.87 5.59 0.45 1.37e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10489202 0.826 rs202255 chr1:167988653 A/G cg24449463 chr1:168025552 DCAF6 -0.5 -5.28 -0.43 5.67e-7 Schizophrenia; TGCT trans rs28735056 0.572 rs4799100 chr18:77640207 A/G cg05926928 chr17:57297772 GDPD1 -0.83 -9.57 -0.65 1.42e-16 Schizophrenia; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg10150615 chr22:24372951 LOC391322 -0.92 -9.98 -0.67 1.44e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2580764 0.503 rs2972097 chr2:55267545 T/C cg09592903 chr2:55203963 RTN4 0.27 6.24 0.49 6.34e-9 Mean platelet volume; TGCT cis rs17376456 0.877 rs10050465 chr5:93349963 C/A cg25358565 chr5:93447407 FAM172A 0.92 8.37 0.6 1.05e-13 Diabetic retinopathy; TGCT cis rs2880765 0.566 rs17553249 chr15:86006694 A/G cg13263323 chr15:86062960 AKAP13 -0.22 -4.75 -0.39 5.62e-6 Coronary artery disease; TGCT cis rs7267979 0.934 rs4815423 chr20:25387521 A/G cg16686733 chr20:25566563 NINL -0.59 -5.97 -0.47 2.28e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs713587 0.520 rs483428 chr2:25305136 A/G cg01884057 chr2:25150051 NA 0.26 4.89 0.4 3.08e-6 Body mass index in non-asthmatics; TGCT cis rs7666738 0.830 rs17027090 chr4:98897923 G/T cg05340658 chr4:99064831 C4orf37 0.51 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg16145915 chr7:1198662 ZFAND2A -0.52 -6.75 -0.52 5.07e-10 Longevity;Endometriosis; TGCT cis rs2242116 0.833 rs6442038 chr3:46960742 A/G cg02527881 chr3:46936655 PTH1R -0.33 -6.17 -0.48 9.07e-9 Birth weight; TGCT cis rs763014 0.932 rs35067229 chr16:649638 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.39 -0.6 9.08e-14 Height; TGCT cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg13393036 chr8:95962371 TP53INP1 -0.62 -8.38 -0.6 9.62e-14 Type 2 diabetes; TGCT cis rs7044106 0.762 rs7024046 chr9:123419178 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.63 6.68 0.51 7.09e-10 Hip circumference adjusted for BMI; TGCT cis rs798554 1.000 rs798560 chr7:2758309 A/G cg04166393 chr7:2884313 GNA12 0.6 4.44 0.37 1.97e-5 Height; TGCT cis rs13217239 0.646 rs7451149 chr6:27057518 A/G cg26531700 chr6:26746687 NA -0.72 -7.35 -0.55 2.33e-11 Schizophrenia; TGCT cis rs8177179 0.967 rs6439436 chr3:133453779 C/T cg16262614 chr3:133464971 TF -0.35 -4.82 -0.4 4.19e-6 Iron status biomarkers (transferrin levels); TGCT cis rs2832191 0.740 rs13048618 chr21:30458684 A/G cg24692254 chr21:30365293 RNF160 0.98 11.36 0.71 6.16e-21 Dental caries; TGCT cis rs62064224 0.791 rs11653160 chr17:30717222 A/G cg18200150 chr17:30822561 MYO1D 0.58 7.69 0.57 3.92e-12 Schizophrenia; TGCT cis rs2404602 0.647 rs2404600 chr15:77173557 C/T cg22467129 chr15:76604101 ETFA 0.47 4.79 0.4 4.69e-6 Blood metabolite levels; TGCT cis rs8077577 0.945 rs62073609 chr17:18071843 T/C cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs9467773 0.967 rs9461267 chr6:26525455 T/G cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs7100689 0.646 rs7899791 chr10:82091950 A/T cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs17401966 0.838 rs10492971 chr1:10342975 G/A cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs28386778 0.831 rs2584618 chr17:61923611 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs617791 0.508 rs10791837 chr11:65774596 C/T cg09783858 chr11:65769428 EIF1AD;BANF1 0.49 4.49 0.37 1.64e-5 Breast cancer; TGCT cis rs7267979 1.000 rs2500443 chr20:25331442 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11105298 0.891 rs12369195 chr12:89934972 G/C cg00757033 chr12:89920650 WDR51B 0.3 4.71 0.39 6.56e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs916888 0.821 rs199507 chr17:44858855 A/G cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1008375 0.966 rs6837664 chr4:17697835 G/C cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs904251 0.523 rs10947675 chr6:37479972 G/A cg08126542 chr6:37504118 NA -0.44 -6.36 -0.5 3.49e-9 Cognitive performance; TGCT cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg18230493 chr5:56204884 C5orf35 -0.72 -6.07 -0.48 1.44e-8 Initial pursuit acceleration; TGCT cis rs9611519 1.000 rs4820433 chr22:41607065 C/G cg13695892 chr22:41940480 POLR3H -0.51 -4.71 -0.39 6.49e-6 Neuroticism; TGCT cis rs7727544 0.636 rs2631365 chr5:131705949 T/C cg24060327 chr5:131705240 SLC22A5 0.59 6.59 0.51 1.12e-9 Blood metabolite levels; TGCT cis rs2836974 1.000 rs28360661 chr21:40681972 G/C cg11890956 chr21:40555474 PSMG1 1.05 10.55 0.69 5.98e-19 Cognitive function; TGCT cis rs1218582 0.774 rs4845679 chr1:154861187 G/T cg24250549 chr1:154909240 PMVK 0.58 5.63 0.45 1.15e-7 Prostate cancer; TGCT cis rs11718455 1.000 rs9854785 chr3:44031295 A/G cg08738300 chr3:44038990 NA 0.85 6.49 0.5 1.87e-9 Coronary artery disease; TGCT cis rs7296418 0.961 rs949143 chr12:123595163 G/A cg00376283 chr12:123451042 ABCB9 0.84 7.58 0.56 7.14e-12 Platelet count; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg12419862 chr22:24373484 LOC391322 -0.81 -8.56 -0.61 3.71e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6500602 0.702 rs9929475 chr16:4540885 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.31 -5.57 -0.45 1.48e-7 Schizophrenia; TGCT cis rs2404602 0.698 rs12909656 chr15:76664378 A/T cg22467129 chr15:76604101 ETFA 0.45 4.57 0.38 1.14e-5 Blood metabolite levels; TGCT cis rs4927850 0.881 rs7624638 chr3:195748729 C/T cg22891161 chr3:195456627 MUC20 -0.23 -5.35 -0.43 4.08e-7 Pancreatic cancer; TGCT cis rs921968 0.643 rs678218 chr2:219379709 C/A cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs1670533 1.000 rs6812586 chr4:1069851 A/G cg27284194 chr4:1044797 NA 0.69 5.94 0.47 2.66e-8 Recombination rate (females); TGCT cis rs7100689 0.784 rs10736341 chr10:82061206 C/G cg01528321 chr10:82214614 TSPAN14 0.8 7.9 0.58 1.29e-12 Post bronchodilator FEV1; TGCT cis rs317689 0.690 rs10878947 chr12:69642683 A/T cg11871910 chr12:69753446 YEATS4 0.53 4.47 0.37 1.77e-5 Response to diuretic therapy; TGCT cis rs9611565 0.559 rs132765 chr22:42008068 A/G cg06634786 chr22:41940651 POLR3H 0.89 8.56 0.61 3.56e-14 Vitiligo; TGCT cis rs7614311 0.636 rs73117057 chr3:63915689 A/G cg22134162 chr3:63841271 THOC7 -0.49 -6.17 -0.48 8.78e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs12210905 0.688 rs12194842 chr6:27367978 A/C cg08851530 chr6:28072375 NA 1.33 5.85 0.47 4.08e-8 Hip circumference adjusted for BMI; TGCT cis rs6951245 1.000 rs78143408 chr7:1096846 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1018836 0.663 rs12674903 chr8:91475774 T/C cg16814680 chr8:91681699 NA -0.85 -8.77 -0.62 1.17e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs72781680 0.846 rs72780198 chr2:24014883 T/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg22029157 chr1:209979665 IRF6 0.77 6.04 0.48 1.65e-8 Cleft lip with or without cleft palate; TGCT cis rs2239547 0.525 rs2246556 chr3:53027983 T/C cg10802521 chr3:52805072 NEK4 0.53 5.58 0.45 1.45e-7 Schizophrenia; TGCT cis rs2153535 0.580 rs2225765 chr6:8481785 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs904251 0.522 rs882322 chr6:37484103 A/G cg25019722 chr6:37503610 NA -0.51 -7.96 -0.58 9.09e-13 Cognitive performance; TGCT cis rs9527 0.590 rs7087040 chr10:104799668 G/A cg15744005 chr10:104629667 AS3MT -0.4 -4.63 -0.38 9.04e-6 Arsenic metabolism; TGCT cis rs35146811 0.735 rs1636978 chr7:99813912 G/A cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs7552404 1.000 rs4949874 chr1:76161889 T/C cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.56 -5.24 -0.43 6.59e-7 Prudent dietary pattern; TGCT cis rs3741404 0.620 rs882147 chr11:63976689 T/A cg00022866 chr11:64108440 CCDC88B 0.24 4.55 0.38 1.26e-5 Platelet count; TGCT cis rs2013441 1.000 rs2526460 chr17:20086352 G/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs9473924 0.580 rs67092917 chr6:50815333 G/T cg14470998 chr6:50812995 TFAP2B 1.36 8.61 0.61 2.74e-14 Body mass index; TGCT cis rs7104764 1.000 rs7128044 chr11:244115 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs4642101 0.597 rs9839768 chr3:12821403 C/T cg05775895 chr3:12838266 CAND2 0.92 11.11 0.71 2.54e-20 QRS complex (12-leadsum); TGCT cis rs4237845 0.537 rs11172369 chr12:58280592 T/C cg23860436 chr12:58378763 NA 0.33 4.54 0.38 1.32e-5 Intelligence (multi-trait analysis); TGCT cis rs12682352 0.602 rs28399241 chr8:8663215 C/T cg15556689 chr8:8085844 FLJ10661 0.62 5.37 0.43 3.71e-7 Neuroticism; TGCT cis rs2404602 0.536 rs11072599 chr15:76774508 T/C cg22467129 chr15:76604101 ETFA -0.5 -5.96 -0.47 2.4e-8 Blood metabolite levels; TGCT cis rs9611565 0.694 rs9611591 chr22:41830212 G/A cg06481639 chr22:41940642 POLR3H 0.6 5.31 0.43 4.95e-7 Vitiligo; TGCT cis rs7119 0.651 rs35657172 chr15:77847813 T/C cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT trans rs561341 1.000 rs2470267 chr17:30274132 G/A cg20587970 chr11:113659929 NA -1.0 -10.69 -0.69 2.67e-19 Hip circumference adjusted for BMI; TGCT cis rs12477438 0.798 rs13393860 chr2:99590397 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs4253772 0.550 rs6008601 chr22:46705326 C/G cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs6430585 0.527 rs62168833 chr2:136449254 G/A cg07169764 chr2:136633963 MCM6 1.0 9.14 0.63 1.51e-15 Corneal structure; TGCT cis rs4819052 0.851 rs2877018 chr21:46658306 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9467711 0.606 rs9393718 chr6:26407482 G/A cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12479064 0.505 rs62153764 chr2:99818612 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.79 -6.36 -0.5 3.46e-9 Chronic sinus infection; TGCT cis rs9611565 0.608 rs2003816 chr22:42095140 T/G cg06634786 chr22:41940651 POLR3H 0.82 7.76 0.57 2.71e-12 Vitiligo; TGCT cis rs1005277 0.505 rs10827835 chr10:38150709 G/A cg13531842 chr10:38383804 ZNF37A 0.39 4.58 0.38 1.12e-5 Extrinsic epigenetic age acceleration; TGCT cis rs8103278 0.507 rs7260651 chr19:46260245 G/A cg14061069 chr19:46274453 DMPK 0.63 10.73 0.69 2.08e-19 Coronary artery disease; TGCT trans rs4765905 0.500 rs2239033 chr12:2337746 C/A cg13866577 chr1:66797481 PDE4B -0.49 -6.78 -0.52 4.43e-10 Schizophrenia; TGCT cis rs2420915 0.841 rs7072244 chr10:122873026 G/A cg23234726 chr10:122735589 NA -0.39 -4.49 -0.37 1.6e-5 Fibrinogen levels; TGCT cis rs2153535 0.542 rs915354 chr6:8440357 T/C cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.38e-7 Motion sickness; TGCT cis rs66731853 0.769 rs657624 chr1:20888348 C/T cg04087271 chr1:20915334 CDA -0.52 -6.45 -0.5 2.3e-9 Mean corpuscular volume; TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg05064044 chr6:292385 DUSP22 -0.7 -7.29 -0.55 3.15e-11 Menopause (age at onset); TGCT cis rs12458462 0.892 rs12456692 chr18:77482189 C/T cg11879182 chr18:77439856 CTDP1 0.71 8.06 0.59 5.49e-13 Monocyte count; TGCT cis rs11648796 0.757 rs3809666 chr16:764753 C/G cg00908189 chr16:619842 PIGQ 0.72 5.83 0.46 4.58e-8 Height; TGCT cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1595825 0.891 rs16824631 chr2:198708695 T/G cg19156104 chr2:198669113 PLCL1 -0.58 -4.44 -0.37 1.99e-5 Ulcerative colitis; TGCT cis rs78456975 0.527 rs10203194 chr2:1558021 A/G cg12573674 chr2:1569213 NA -0.45 -4.76 -0.39 5.37e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9929218 0.581 rs12185157 chr16:68784587 G/A cg01251360 chr16:68772225 CDH1 -0.25 -4.61 -0.38 9.8200000000000008e-06 Colorectal cancer; TGCT cis rs4824093 0.610 rs12106611 chr22:50242686 G/A cg14114931 chr22:50943910 LMF2 0.36 4.53 0.38 1.37e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs13191362 1.000 rs34398656 chr6:162999612 G/T cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg06481639 chr22:41940642 POLR3H -0.73 -6.69 -0.51 6.99e-10 Vitiligo; TGCT cis rs57590327 0.508 rs4399914 chr3:81965477 C/T cg07356753 chr3:81810745 GBE1 -0.65 -5.69 -0.46 8.57e-8 Extraversion; TGCT cis rs2469997 0.843 rs2470030 chr8:120368991 T/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs7914558 0.966 rs4532960 chr10:104667406 C/T cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs778371 0.624 rs6733495 chr2:233616709 A/G cg08000102 chr2:233561755 GIGYF2 0.72 8.68 0.61 1.91e-14 Schizophrenia; TGCT cis rs35146811 0.735 rs11767968 chr7:99790971 G/A cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs12210905 0.688 rs72841398 chr6:27489114 A/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs8081395 0.741 rs1292053 chr17:57963537 C/T cg16369400 chr17:58041258 RNFT1 -0.22 -4.46 -0.37 1.8e-5 White blood cell count; TGCT cis rs2338224 0.800 rs6874695 chr5:71742444 C/T cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs3091242 0.934 rs666686 chr1:25719511 A/G cg23205692 chr1:25664452 TMEM50A 0.49 5.07 0.41 1.39e-6 Erythrocyte sedimentation rate; TGCT cis rs907683 0.533 rs12469789 chr2:220293242 C/T cg15015639 chr2:220282977 DES 0.4 5.11 0.42 1.18e-6 Resting heart rate; TGCT cis rs28785552 0.769 rs28796114 chr19:53234319 T/C cg10871876 chr19:53194124 ZNF83 0.6 8.53 0.61 4.35e-14 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs597539 0.652 rs516425 chr11:68715675 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.83 7.83 0.58 1.82e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1552244 0.882 rs35056669 chr3:10014171 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.6 -0.51 1.06e-9 Alzheimer's disease; TGCT cis rs1451375 0.741 rs55738142 chr7:50632326 T/C cg18232548 chr7:50535776 DDC 0.43 6.57 0.51 1.26e-9 Malaria; TGCT cis rs9902453 0.726 rs4795523 chr17:28176314 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.39 0.6 8.97e-14 Coffee consumption (cups per day); TGCT cis rs9308731 0.644 rs4849403 chr2:111874037 T/C cg04202892 chr2:111875749 ACOXL 0.54 6.22 0.49 7.04e-9 Chronic lymphocytic leukemia; TGCT cis rs514406 0.825 rs6693210 chr1:53223398 A/G cg25767906 chr1:53392781 SCP2 0.5 5.71 0.46 7.74e-8 Monocyte count; TGCT cis rs7809950 0.731 rs2712196 chr7:107128797 G/T cg23024343 chr7:107201750 COG5 -0.46 -6.9 -0.53 2.4e-10 Coronary artery disease; TGCT cis rs3820928 0.874 rs2229812 chr2:227896886 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs514406 0.798 rs575138 chr1:53328394 C/G cg24675658 chr1:53192096 ZYG11B -0.78 -9.21 -0.64 1.01e-15 Monocyte count; TGCT cis rs7666738 0.830 rs7680909 chr4:98934604 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6088580 0.634 rs6059868 chr20:33079460 A/G cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs7786808 0.712 rs12671981 chr7:158202971 G/A cg01191920 chr7:158217561 PTPRN2 -0.45 -6.84 -0.52 3.22e-10 Obesity-related traits; TGCT cis rs4389656 0.857 rs274713 chr5:6723560 A/C cg10857441 chr5:6722123 POLS -0.22 -4.82 -0.4 4.07e-6 Coronary artery disease; TGCT cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg13395646 chr4:1353034 KIAA1530 -0.39 -4.96 -0.41 2.3e-6 Obesity-related traits; TGCT cis rs6089584 0.927 rs2296083 chr20:60574216 C/T cg06108461 chr20:60628389 TAF4 -0.58 -8.21 -0.59 2.37e-13 Body mass index; TGCT cis rs68170813 0.559 rs7794965 chr7:106826439 A/G cg02696742 chr7:106810147 HBP1 0.72 6.28 0.49 5.29e-9 Coronary artery disease; TGCT cis rs7647973 0.922 rs57273516 chr3:49483074 A/G cg07636037 chr3:49044803 WDR6 0.64 5.26 0.43 6.12e-7 Menarche (age at onset); TGCT trans rs1005277 0.579 rs2800485 chr10:38542588 G/A cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs7681440 0.904 rs17192189 chr4:90774928 A/C cg20003494 chr4:90757398 SNCA 0.51 4.68 0.39 7.52e-6 Dementia with Lewy bodies; TGCT cis rs4478037 0.555 rs60749629 chr3:33105319 G/A cg19404215 chr3:33155277 CRTAP 1.16 5.14 0.42 1.05e-6 Major depressive disorder; TGCT cis rs10811516 0.501 rs10283817 chr9:21159319 T/C cg23029519 chr9:21187344 IFNA4 -0.3 -4.61 -0.38 9.72e-6 Response to mepolizumab in severe asthma; TGCT cis rs6570726 0.935 rs372378 chr6:145816227 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10779751 1.000 rs7524202 chr1:11297762 T/C cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs9303401 0.659 rs34170300 chr17:56789905 G/C cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs2070488 0.965 rs7373828 chr3:38524311 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.17 0.64 1.25e-15 Electrocardiographic conduction measures; TGCT cis rs7937682 0.883 rs1613778 chr11:111456105 G/C cg09085632 chr11:111637200 PPP2R1B -0.97 -9.75 -0.66 5.24e-17 Primary sclerosing cholangitis; TGCT cis rs11671005 0.695 rs8106061 chr19:58917990 G/C cg11952622 chr19:58962976 ZNF324B 0.75 6.72 0.52 5.95e-10 Mean platelet volume; TGCT cis rs72945132 0.882 rs7941933 chr11:70123351 G/A cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg12386194 chr3:101231763 SENP7 0.48 4.68 0.39 7.26e-6 Colorectal cancer; TGCT cis rs6546537 0.785 rs4852863 chr2:69814609 A/T cg10773587 chr2:69614142 GFPT1 -0.81 -7.43 -0.55 1.57e-11 Serum thyroid-stimulating hormone levels; TGCT cis rs36051895 0.658 rs10974912 chr9:5010885 A/C cg02405213 chr9:5042618 JAK2 -0.76 -10.25 -0.68 3.06e-18 Pediatric autoimmune diseases; TGCT cis rs12142240 0.698 rs10158236 chr1:46820896 G/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs11785400 0.793 rs6996760 chr8:143722386 G/A cg10596483 chr8:143751796 JRK 0.53 5.23 0.43 7.02e-7 Schizophrenia; TGCT cis rs1667284 0.510 rs1791228 chr18:29179040 C/T cg15259973 chr18:29078565 DSG2 0.47 4.49 0.37 1.61e-5 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs2013441 0.965 rs7207611 chr17:20204516 C/T cg18979559 chr17:20280153 CCDC144C 0.49 4.99 0.41 1.97e-6 Obesity-related traits; TGCT cis rs10751667 0.643 rs6597970 chr11:928669 C/A cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs1552244 1.000 rs67134728 chr3:10151431 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs700590 0.532 rs17558396 chr5:88102281 T/G cg24804195 chr5:87968844 LOC645323 -0.48 -4.48 -0.37 1.7e-5 Educational attainment (years of education); TGCT cis rs35160687 0.842 rs10200526 chr2:86527599 G/A cg04877910 chr2:85804641 VAMP8 0.34 4.51 0.38 1.49e-5 Night sleep phenotypes; TGCT cis rs172166 0.516 rs1150670 chr6:28130559 A/G cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.71 -0.39 6.43e-6 Cardiac Troponin-T levels; TGCT cis rs1008375 0.932 rs9884565 chr4:17655096 A/G cg16339924 chr4:17578868 LAP3 0.67 5.48 0.44 2.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.862 rs709596 chr7:65825913 A/G cg11764359 chr7:65958608 NA 0.56 5.11 0.42 1.17e-6 Aortic root size; TGCT cis rs35146811 0.695 rs1623264 chr7:99811204 G/C cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs17152411 0.895 rs7900929 chr10:126584999 A/C cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs68170813 0.559 rs77641084 chr7:106970522 G/A cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs72781680 0.898 rs2879640 chr2:24043573 T/C cg08917208 chr2:24149416 ATAD2B 0.8 4.93 0.4 2.62e-6 Lymphocyte counts; TGCT cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg24531977 chr5:56204891 C5orf35 0.97 9.1 0.63 1.86e-15 Initial pursuit acceleration; TGCT cis rs3733585 0.699 rs7663079 chr4:9966771 T/C cg00071950 chr4:10020882 SLC2A9 -0.57 -6.85 -0.52 3.12e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs981844 0.712 rs11099915 chr4:154743624 A/G cg14289246 chr4:154710475 SFRP2 -1.0 -9.26 -0.64 7.7e-16 Response to statins (LDL cholesterol change); TGCT cis rs10883723 0.668 rs12414479 chr10:104420902 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.78 7.31 0.55 2.8e-11 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1799949 1.000 rs1060915 chr17:41234470 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.6e-6 Menopause (age at onset); TGCT cis rs17423910 0.950 rs12135034 chr1:66646184 A/G cg04880992 chr1:67434664 MIER1 -0.31 -4.5 -0.37 1.53e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs10782582 0.609 rs11584577 chr1:76242378 A/G cg03433033 chr1:76189801 ACADM -0.45 -4.6 -0.38 1.02e-5 Daytime sleep phenotypes; TGCT cis rs4319547 0.656 rs3817011 chr12:122819566 C/T cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.62 -0.38 9.46e-6 Body mass index; TGCT cis rs1992660 0.504 rs10941505 chr5:40399246 G/A cg01087697 chr5:40835557 RPL37 0.54 4.93 0.4 2.6e-6 Crohn's disease; TGCT cis rs1475911 0.708 rs66994219 chr21:43521647 G/A cg24372256 chr21:43528868 UMODL1;C21orf128 -0.31 -5.84 -0.46 4.24e-8 IgG glycosylation; TGCT cis rs9534288 0.700 rs4942466 chr13:46597190 A/G cg15192986 chr13:46630673 CPB2 -0.49 -6.92 -0.53 2.11e-10 Blood protein levels; TGCT cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 -1.15 -10.22 -0.68 3.75e-18 Platelet count; TGCT cis rs2594989 0.887 rs2454513 chr3:11549596 C/T cg00170343 chr3:11313890 ATG7 0.65 4.58 0.38 1.13e-5 Circulating chemerin levels; TGCT trans rs4332037 0.950 rs11767515 chr7:1941051 C/T cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs911555 0.755 rs6575988 chr14:103900827 G/T cg12935359 chr14:103987150 CKB 0.32 4.47 0.37 1.73e-5 Intelligence (multi-trait analysis); TGCT cis rs709400 0.859 rs942863 chr14:104021268 C/T cg26031613 chr14:104095156 KLC1 1.19 16.9 0.83 5.78e-34 Body mass index; TGCT cis rs11190604 0.767 rs11190519 chr10:102175133 C/T cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2243480 1.000 rs2961102 chr7:65424658 A/G cg20637647 chr7:64974828 NA 0.96 5.61 0.45 1.26e-7 Diabetic kidney disease; TGCT cis rs4466137 1.000 rs4466137 chr5:82985739 A/C cg16102102 chr5:83017553 HAPLN1 -0.91 -11.43 -0.72 4.29e-21 Prostate cancer; TGCT cis rs4494114 0.967 rs9438991 chr1:39376504 G/A cg25970120 chr1:39325951 RRAGC -0.59 -5.86 -0.47 3.9e-8 Blood protein levels; TGCT cis rs11190604 1.000 rs2495751 chr10:102327260 A/G cg23241863 chr10:102295624 HIF1AN 0.67 5.1 0.42 1.23e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3007729 1.000 rs3007729 chr1:18795255 A/G cg13507429 chr1:18807550 KLHDC7A -0.34 -5.03 -0.41 1.65e-6 Diabetic retinopathy; TGCT cis rs7100689 0.646 rs10749581 chr10:82141651 A/G cg01528321 chr10:82214614 TSPAN14 -0.81 -8.6 -0.61 2.92e-14 Post bronchodilator FEV1; TGCT cis rs9611565 0.592 rs28750375 chr22:41990644 A/C cg03806693 chr22:41940476 POLR3H -1.01 -10.2 -0.68 4.07e-18 Vitiligo; TGCT cis rs4499344 0.526 rs8100915 chr19:33032310 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.64 -5.58 -0.45 1.44e-7 Mean platelet volume; TGCT cis rs3138083 0.607 rs12376134 chr9:35643284 C/T cg07116010 chr9:35646325 NA 0.82 10.29 0.68 2.44e-18 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel); TGCT cis rs11577318 0.853 rs7537477 chr1:26618829 C/T cg12733254 chr1:26682999 NA -0.2 -4.67 -0.39 7.71e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4733770 0.581 rs12550366 chr8:131136047 A/T cg16277922 chr8:131349729 ASAP1 0.44 6.55 0.51 1.41e-9 Schizophrenia; TGCT cis rs6693567 0.565 rs696615 chr1:150338988 A/C cg09579323 chr1:150459698 TARS2 0.52 4.57 0.38 1.15e-5 Migraine; TGCT cis rs7523273 0.565 rs3927459 chr1:207883907 A/C cg22525895 chr1:207977042 MIR29B2 0.32 5.16 0.42 9.52e-7 Schizophrenia; TGCT cis rs9322193 0.884 rs9371201 chr6:150145001 C/T cg13206674 chr6:150067644 NUP43 0.54 4.61 0.38 1e-5 Lung cancer; TGCT cis rs7095607 0.813 rs7908489 chr10:69932557 C/T cg18986048 chr10:69913749 MYPN 0.44 4.92 0.4 2.64e-6 Lung function (FVC); TGCT cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg24829409 chr8:58192753 C8orf71 -0.57 -4.72 -0.39 6.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs13256369 0.760 rs7839473 chr8:8575836 C/T cg17143192 chr8:8559678 CLDN23 0.63 5.93 0.47 2.8e-8 Obesity-related traits; TGCT cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg07092213 chr7:1199455 ZFAND2A -0.5 -5.84 -0.46 4.32e-8 Longevity;Endometriosis; TGCT cis rs28595532 0.841 rs115924581 chr4:119786333 T/C cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs9402673 0.558 rs9688342 chr6:135323026 A/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Reticulocyte count;High light scatter reticulocyte count; TGCT cis rs8013055 0.796 rs28662250 chr14:105996341 C/G cg23356831 chr14:105996513 TMEM121 0.34 5.04 0.41 1.62e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7618915 0.547 rs13085331 chr3:52627486 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg05785598 chr3:49045655 WDR6 0.37 4.87 0.4 3.34e-6 Menarche (age at onset); TGCT cis rs7017914 0.967 rs1596566 chr8:71698576 A/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs244731 0.920 rs244707 chr5:176555636 A/T cg06060754 chr5:176797920 RGS14 0.44 5.89 0.47 3.45e-8 Urate levels in lean individuals; TGCT cis rs9660180 0.967 rs61422524 chr1:1767565 C/A cg03396347 chr1:1875803 NA -0.38 -6.74 -0.52 5.2400000000000005e-10 Body mass index; TGCT cis rs259282 0.605 rs36107586 chr19:33109674 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.33 0.43 4.48e-7 Schizophrenia; TGCT cis rs2204008 0.635 rs1283298 chr12:38147630 G/A cg26384229 chr12:38710491 ALG10B -0.58 -5.08 -0.42 1.34e-6 Bladder cancer; TGCT cis rs7726839 0.540 rs72703083 chr5:595365 C/T cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs2645424 0.635 rs6980952 chr8:11716473 C/G cg21281001 chr8:11725306 CTSB -0.54 -4.49 -0.37 1.59e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs13191362 1.000 rs34918316 chr6:163005386 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10032931 0.962 rs7686970 chr4:96457107 G/A cg17031751 chr4:96469067 UNC5C -0.41 -4.95 -0.41 2.35e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs854765 0.718 rs6502629 chr17:17869642 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.67 6.54 0.51 1.47e-9 Total body bone mineral density; TGCT cis rs4808199 0.947 rs4808960 chr19:19574277 G/C cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.15 0.42 9.94e-7 Nonalcoholic fatty liver disease; TGCT cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg23758822 chr17:41437982 NA 0.65 6.4 0.5 2.97e-9 Menopause (age at onset); TGCT cis rs7666738 0.830 rs6846229 chr4:99016546 C/T cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs988712 0.622 rs10767664 chr11:27725986 T/A cg10635145 chr11:27742435 BDNF 0.44 6.37 0.5 3.35e-9 Obesity; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg23156509 chr2:114033830 PAX8;LOC440839 -0.31 -4.83 -0.4 3.92e-6 Lymphocyte counts; TGCT cis rs1385374 0.858 rs11059926 chr12:129294244 A/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs1669338 1.000 rs1669338 chr3:3199635 A/C cg16797762 chr3:3221439 CRBN 0.69 4.72 0.39 6.15e-6 White matter integrity; TGCT cis rs7666738 0.791 rs13125277 chr4:99009922 T/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8077889 0.917 rs72836559 chr17:41913529 C/T cg26893861 chr17:41843967 DUSP3 1.08 12.97 0.76 7.86e-25 Triglycerides; TGCT cis rs6964587 0.967 rs13233496 chr7:91813035 T/C cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.65e-6 Breast cancer; TGCT cis rs6866344 0.697 rs11748495 chr5:178130000 A/G cg10224037 chr5:178157518 ZNF354A -0.96 -8.44 -0.6 7.15e-14 Neutrophil percentage of white cells; TGCT cis rs2239547 0.657 rs2276817 chr3:52860936 C/T cg11645453 chr3:52864694 ITIH4 0.34 5.67 0.45 9.34e-8 Schizophrenia; TGCT cis rs6089829 0.962 rs6062776 chr20:61663736 A/G cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7552404 0.924 rs2153126 chr1:76199345 C/G cg22875332 chr1:76189707 ACADM 0.77 9.49 0.65 2.13e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3784262 1.000 rs4646627 chr15:58255305 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.7 -0.57 3.78e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9303401 0.659 rs9303399 chr17:56672309 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.16 0.48 9.32e-9 Cognitive test performance; TGCT cis rs7119 0.717 rs12901471 chr15:77818992 A/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.61 -0.38 1e-5 Type 2 diabetes; TGCT cis rs611744 0.934 rs1668178 chr8:109191700 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs11671005 0.651 rs11878203 chr19:58920050 G/A cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT cis rs769267 0.896 rs2074298 chr19:19377716 C/G cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs2762353 0.574 rs9467570 chr6:25699283 C/A cg03517284 chr6:25882590 NA 0.91 9.09 0.63 1.99e-15 Blood metabolite levels; TGCT cis rs739496 0.614 rs7137889 chr12:112379587 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs2290402 0.536 rs4690203 chr4:881228 C/T cg23332689 chr4:987652 IDUA;SLC26A1 0.33 5.0 0.41 1.94e-6 Type 2 diabetes; TGCT cis rs2932538 0.961 rs2932539 chr1:113215786 A/G cg22162597 chr1:113214053 CAPZA1 -0.28 -6.31 -0.49 4.46e-9 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg20007245 chr22:24372913 LOC391322 -0.66 -6.2 -0.49 7.68e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.535 rs6850010 chr4:98971601 A/T cg17366294 chr4:99064904 C4orf37 0.65 6.3 0.49 4.76e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs3846443 chr4:99032666 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2932538 0.922 rs6690169 chr1:113114974 A/G cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs11190604 1.000 rs2489053 chr10:102353341 A/G cg23241863 chr10:102295624 HIF1AN 0.76 5.49 0.44 2.22e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg13877915 chr19:58951672 ZNF132 0.91 11.55 0.72 2.15e-21 Uric acid clearance; TGCT cis rs6882046 0.513 rs647983 chr5:88048071 T/C cg24804195 chr5:87968844 LOC645323 -0.57 -5.69 -0.46 8.66e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs57590327 0.679 rs35381070 chr3:81590374 G/A cg07356753 chr3:81810745 GBE1 -0.54 -4.53 -0.38 1.38e-5 Extraversion; TGCT cis rs12549902 0.800 rs4736999 chr8:41506152 C/G cg21772509 chr8:41503840 NKX6-3 0.81 9.15 0.63 1.42e-15 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT trans rs1496653 0.602 rs71322185 chr3:23470528 A/G cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs9443645 0.901 rs971994 chr6:79559602 G/C cg09184832 chr6:79620586 NA -0.48 -5.35 -0.43 4.01e-7 Intelligence (multi-trait analysis); TGCT cis rs61931739 0.500 rs7298322 chr12:34445489 A/T cg06521331 chr12:34319734 NA -0.28 -4.51 -0.38 1.47e-5 Morning vs. evening chronotype; TGCT cis rs13242816 1.000 rs13226307 chr7:116137485 A/T cg02799643 chr7:116139180 CAV2 0.46 5.92 0.47 3e-8 P wave duration; TGCT cis rs7017914 0.934 rs1389202 chr8:71852285 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.29 -0.43 5.4e-7 Bone mineral density; TGCT cis rs669446 0.591 rs607062 chr1:44133016 A/G cg12908607 chr1:44402522 ARTN -0.52 -5.89 -0.47 3.37e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs12497850 1.000 rs4858798 chr3:48727112 C/T cg07636037 chr3:49044803 WDR6 0.92 10.35 0.68 1.74e-18 Parkinson's disease; TGCT cis rs10992471 0.603 rs7865019 chr9:95325631 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.71 -0.46 7.82e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6424115 0.800 rs2229583 chr1:24200983 C/T cg15997130 chr1:24165203 NA 0.85 9.35 0.64 4.75e-16 Immature fraction of reticulocytes; TGCT cis rs13256369 0.901 rs12681298 chr8:8566235 A/G cg18904891 chr8:8559673 CLDN23 -0.59 -5.5 -0.44 2.11e-7 Obesity-related traits; TGCT cis rs858239 0.601 rs10224327 chr7:23161820 T/C cg05602783 chr7:23145260 KLHL7 -0.7 -6.14 -0.48 1.03e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs7127900 0.614 rs11564708 chr11:2206326 C/G cg08005462 chr11:2212133 NA -0.28 -4.5 -0.37 1.53e-5 Prostate cancer;Prostate cancer (SNP x SNP interaction);Prostate cancer (early onset); TGCT cis rs6121246 0.528 rs6060252 chr20:30191084 A/G cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs2013441 1.000 rs1561974 chr17:20196144 G/A cg18979559 chr17:20280153 CCDC144C -0.49 -5.04 -0.41 1.59e-6 Obesity-related traits; TGCT cis rs8056893 0.686 rs10775304 chr16:68411162 C/T cg02226672 chr16:68398533 SMPD3 0.21 4.47 0.37 1.72e-5 Blood metabolite ratios;Glomerular filtration rate (creatinine);Blood metabolite levels; TGCT cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg03264133 chr6:25882463 NA -0.67 -6.3 -0.49 4.73e-9 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs57306627 chr5:597643 T/C cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs600231 0.508 rs11227202 chr11:65242717 G/A cg17120908 chr11:65337727 SSSCA1 -0.57 -4.45 -0.37 1.9e-5 Bone mineral density; TGCT trans rs11088226 0.681 rs2833926 chr21:33975279 A/G cg09050820 chr6:167586206 TCP10L2 0.76 7.3 0.55 3.04e-11 Gastritis; TGCT cis rs739496 0.895 rs7977752 chr12:111850230 G/A cg10833066 chr12:111807467 FAM109A 0.37 4.95 0.41 2.32e-6 Platelet count; TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg08859206 chr1:53392774 SCP2 -0.42 -6.8 -0.52 3.92e-10 Monocyte count; TGCT cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg20637647 chr7:64974828 NA 0.94 5.16 0.42 9.35e-7 Diabetic kidney disease; TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs138880 0.542 rs9616393 chr22:50314809 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.22 7.9 0.58 1.3e-12 Schizophrenia; TGCT cis rs11671005 0.735 rs3826681 chr19:58918764 A/G cg13877915 chr19:58951672 ZNF132 0.63 4.92 0.4 2.74e-6 Mean platelet volume; TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs2996428 0.667 rs7545274 chr1:3744261 G/T cg13057898 chr1:3703894 LRRC47 0.21 4.55 0.38 1.27e-5 Red cell distribution width; TGCT cis rs2153535 0.580 rs9406163 chr6:8466642 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs10031466 1.000 rs10031466 chr4:189015402 G/A cg04086012 chr4:189060900 TRIML1 -0.2 -4.53 -0.38 1.38e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs981844 0.816 rs62325151 chr4:154730595 A/G cg14289246 chr4:154710475 SFRP2 1.04 9.12 0.63 1.69e-15 Response to statins (LDL cholesterol change); TGCT cis rs116095464 0.558 rs3213838 chr5:223890 G/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs9467711 0.516 rs555460 chr6:25870655 C/T cg03517284 chr6:25882590 NA -0.77 -5.18 -0.42 8.65e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs11722228 0.522 rs73212817 chr4:10064011 T/C cg26043149 chr18:55253948 FECH 1.1 10.46 0.68 9.51e-19 Gout;Urate levels;Serum uric acid levels; TGCT cis rs6918586 0.658 rs198844 chr6:26108282 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.05e-9 Schizophrenia; TGCT cis rs1005277 0.579 rs932538 chr10:38381314 T/C cg25427524 chr10:38739819 LOC399744 -0.38 -7.91 -0.58 1.23e-12 Extrinsic epigenetic age acceleration; TGCT cis rs11578119 0.866 rs12133032 chr1:170353206 G/C cg09767346 chr1:170501363 GORAB 0.61 4.61 0.38 9.8e-6 Male-pattern baldness; TGCT trans rs10435719 0.867 rs62493601 chr8:11788307 C/T cg15556689 chr8:8085844 FLJ10661 0.78 7.34 0.55 2.46e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs727505 0.909 rs7810427 chr7:124645103 C/T cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs7119038 0.509 rs10892260 chr11:118583525 A/C cg19308663 chr11:118741387 NA 0.25 4.64 0.38 8.77e-6 Sjögren's syndrome; TGCT cis rs737008 0.922 rs376374 chr16:11370616 G/A cg00044050 chr16:11439710 C16orf75 -0.68 -6.92 -0.53 2.12e-10 Obesity-related traits; TGCT cis rs6912958 0.525 rs242262 chr6:88018057 A/C cg12350822 chr6:88032061 C6orf162;GJB7 0.45 5.9 0.47 3.25e-8 Monocyte percentage of white cells; TGCT cis rs4595586 0.525 rs3914597 chr12:39388693 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT trans rs1814175 0.817 rs12277258 chr11:49940216 T/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs929354 0.772 rs4716460 chr7:156970054 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs56235845 0.694 rs12055081 chr5:176757191 C/T cg17509989 chr5:176798049 RGS14 0.55 7.58 0.56 6.89e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs79349575 0.783 rs12602746 chr17:47031741 A/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs1577917 0.958 rs12216074 chr6:86520002 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs7617773 0.817 rs11710861 chr3:48297560 C/T cg11946769 chr3:48343235 NME6 0.72 6.22 0.49 6.83e-9 Coronary artery disease; TGCT cis rs9486715 0.758 rs2971610 chr6:97027380 C/T cg18709589 chr6:96969512 KIAA0776 -0.87 -8.46 -0.61 6.16e-14 Headache; TGCT cis rs9486719 0.901 rs760619 chr6:96857431 A/G cg06623918 chr6:96969491 KIAA0776 0.98 8.23 0.59 2.13e-13 Migraine;Coronary artery disease; TGCT trans rs783396 0.685 rs36016898 chr6:107088231 C/T cg27564810 chr2:201635376 AOX2P 0.5 6.61 0.51 1e-9 Stroke; TGCT cis rs9388451 0.903 rs7758115 chr6:126061502 C/T cg10911889 chr6:126070802 HEY2 0.48 4.82 0.4 4.09e-6 Brugada syndrome; TGCT cis rs9916302 0.851 rs11078904 chr17:37650569 G/A cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs7659604 0.540 rs11734075 chr4:122695685 C/T cg06713675 chr4:122721982 EXOSC9 0.35 4.48 0.37 1.64e-5 Type 2 diabetes; TGCT cis rs4242434 0.726 rs10105545 chr8:22534232 A/G cg03733263 chr8:22462867 KIAA1967 -1.08 -14.87 -0.8 2.45e-29 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs8103278 1.000 rs8102876 chr19:46332842 C/T cg11657440 chr19:46296263 DMWD -0.6 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs3733585 0.673 rs7672947 chr4:9961368 G/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7772486 0.875 rs2777476 chr6:146345024 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.64 0.65 9.38e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2594989 0.943 rs346072 chr3:11306851 A/G cg00170343 chr3:11313890 ATG7 -0.72 -5.13 -0.42 1.08e-6 Circulating chemerin levels; TGCT cis rs10992471 0.528 rs7022562 chr9:95216340 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2921073 0.509 rs2976931 chr8:8257317 C/A cg15556689 chr8:8085844 FLJ10661 0.73 6.64 0.51 8.65e-10 Parkinson's disease; TGCT cis rs644799 0.710 rs12272061 chr11:95524067 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.65 0.61 2.18e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3784262 0.669 rs3784259 chr15:58257847 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.11 -0.48 1.19e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs2070488 1.000 rs13089394 chr3:38446309 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 9.06e-17 Electrocardiographic conduction measures; TGCT cis rs4819052 0.851 rs2236443 chr21:46678174 T/C cg06618935 chr21:46677482 NA -0.39 -5.82 -0.46 4.8e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2290402 0.505 rs9328759 chr4:882845 C/T cg14959580 chr4:1402198 NA -0.4 -4.44 -0.37 1.99e-5 Type 2 diabetes; TGCT cis rs2602836 0.830 rs2602874 chr4:100039396 A/T cg13256891 chr4:100009986 ADH5 0.45 4.67 0.39 7.66e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs763014 0.966 rs4984903 chr16:680695 A/G cg00908189 chr16:619842 PIGQ 0.87 10.68 0.69 2.85e-19 Height; TGCT cis rs7659604 0.502 rs4315813 chr4:122674866 G/A cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.93e-6 Type 2 diabetes; TGCT cis rs7572733 0.534 rs700672 chr2:198691455 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs1691799 0.899 rs1168328 chr12:66729250 T/C cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.87e-9 White blood cell count (basophil); TGCT cis rs7917772 0.636 rs7079231 chr10:104527341 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.58 4.85 0.4 3.6e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg04389838 chr3:44770851 ZNF501 -0.37 -4.81 -0.4 4.37e-6 Depressive symptoms; TGCT cis rs12579753 1.000 rs10862374 chr12:82250809 G/C cg07988820 chr12:82153109 PPFIA2 -0.6 -6.61 -0.51 1.01e-9 Resting heart rate; TGCT cis rs11696501 0.637 rs6130865 chr20:44211845 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.66 -0.39 7.97e-6 Brain structure; TGCT cis rs806215 0.950 rs989099 chr7:127220827 A/G cg25922125 chr7:127225783 GCC1 -0.6 -6.2 -0.49 7.6e-9 Type 2 diabetes; TGCT cis rs7267979 1.000 rs6050544 chr20:25320228 T/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467711 0.606 rs12174631 chr6:26373150 C/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs3806843 1.000 rs1548700 chr5:140164889 A/T cg19875535 chr5:140030758 IK 0.37 6.17 0.48 8.88e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7172809 0.643 rs61097729 chr15:77834358 C/G cg22256960 chr15:77711686 NA -0.49 -4.93 -0.4 2.56e-6 Glucose homeostasis traits; TGCT cis rs57221529 0.709 rs72703034 chr5:577101 C/T cg20362242 chr5:692897 TPPP 0.48 4.51 0.38 1.47e-5 Lung disease severity in cystic fibrosis; TGCT cis rs7412746 0.658 rs2272214 chr1:150931462 C/T cg09365446 chr1:150670422 GOLPH3L 0.32 4.57 0.38 1.15e-5 Melanoma; TGCT cis rs611744 0.967 rs627604 chr8:109189819 C/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs6840360 0.615 rs12503677 chr4:152610543 A/G cg22705602 chr4:152727874 NA -0.36 -5.97 -0.47 2.28e-8 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs6728106 chr2:43683885 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.43 0.37 2.01e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs8056446 1.000 rs12716852 chr16:78188738 C/T cg00663719 chr16:78231199 WWOX 0.27 5.02 0.41 1.72e-6 Pulmonary function (smoking interaction); TGCT cis rs9614461 0.702 rs16993867 chr22:45733199 A/G cg01808030 chr22:45809952 RIBC2;SMC1B 0.77 4.78 0.39 4.88e-6 Tonsillectomy; TGCT cis rs72781680 0.821 rs12616257 chr2:24135034 A/G cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs6463523 0.933 rs6974151 chr7:758269 T/C cg14391382 chr7:866102 UNC84A 0.21 4.65 0.39 8.29e-6 Subjective well-being; TGCT cis rs950880 0.560 rs11685480 chr2:102927086 G/A cg09003973 chr2:102972529 NA -0.52 -4.52 -0.38 1.45e-5 Serum protein levels (sST2); TGCT cis rs12360000 0.770 rs11250852 chr10:1909726 A/G cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs9341808 0.718 rs3828754 chr6:80900640 C/G cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs6500602 0.610 rs1659499 chr16:4595269 G/A cg08645402 chr16:4508243 NA -0.18 -5.16 -0.42 9.69e-7 Schizophrenia; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg07157834 chr1:205819609 PM20D1 0.44 7.12 0.54 7.56e-11 Menarche (age at onset); TGCT cis rs116095464 0.558 rs10076655 chr5:239464 G/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs875971 0.862 rs9791713 chr7:66105198 C/A cg11764359 chr7:65958608 NA -0.55 -4.98 -0.41 2.1e-6 Aortic root size; TGCT cis rs6089584 0.888 rs2146853 chr20:60617908 A/T cg13770153 chr20:60521292 NA -0.54 -7.13 -0.54 7.45e-11 Body mass index; TGCT trans rs2727020 0.636 rs10839275 chr11:49438962 T/A cg15704280 chr7:45808275 SEPT13 -0.73 -8.23 -0.59 2.15e-13 Coronary artery disease; TGCT cis rs2013441 1.000 rs11870147 chr17:20216095 A/G cg23224458 chr17:20280056 CCDC144C -0.39 -4.7 -0.39 6.91e-6 Obesity-related traits; TGCT cis rs9296092 0.500 rs9461885 chr6:33521069 G/T cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs34172651 0.517 rs11647120 chr16:24819806 A/G cg06028605 chr16:24865363 SLC5A11 0.41 4.53 0.38 1.36e-5 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs6818045 chr4:99049374 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2239547 0.657 rs7638524 chr3:52874861 G/A cg10802521 chr3:52805072 NEK4 -0.65 -6.12 -0.48 1.16e-8 Schizophrenia; TGCT cis rs7772486 0.727 rs10223508 chr6:146285205 C/T cg23711669 chr6:146136114 FBXO30 -0.85 -9.52 -0.65 1.86e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6940638 0.956 rs12203454 chr6:27031100 C/T cg26531700 chr6:26746687 NA -0.6 -4.63 -0.38 9.25e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs11725652 chr4:98878362 G/A cg05340658 chr4:99064831 C4orf37 0.53 6.1 0.48 1.22e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12134133 1.000 rs7522618 chr1:207417426 A/G cg02152968 chr1:207494213 CD55 0.61 4.76 0.39 5.4e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs2439831 0.850 rs10163054 chr15:44047638 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs3862435 0.610 rs2601204 chr15:90961518 G/A cg14166756 chr15:90894880 ZNF774 -0.3 -4.6 -0.38 1.02e-5 Response to exercise (triglyceride level interaction); TGCT cis rs986417 0.892 rs11622577 chr14:60814981 A/T cg27398547 chr14:60952738 C14orf39 -1.5 -8.03 -0.58 6.38e-13 Gut microbiota (bacterial taxa); TGCT cis rs11644362 1.000 rs11644362 chr16:12994097 T/C cg06890432 chr16:12997467 SHISA9 -0.61 -6.77 -0.52 4.49e-10 Positive affect;Subjective well-being; TGCT cis rs9916302 0.904 rs7223331 chr17:37482930 A/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs7223966 1.000 rs6504168 chr17:61697469 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.76 0.39 5.39e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs10791097 0.694 rs876641 chr11:130752040 A/C cg14779329 chr11:130786720 SNX19 0.29 5.01 0.41 1.85e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4919694 1.000 rs12252500 chr10:104794984 G/C cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs28595532 0.920 rs28837152 chr4:119782868 G/A cg14228332 chr4:119757509 SEC24D 1.19 6.66 0.51 8.07e-10 Cannabis dependence symptom count; TGCT cis rs10206020 0.885 rs13388254 chr2:1577209 A/G cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs17001868 0.527 rs73167009 chr22:40734249 T/C cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs4499344 0.730 rs392332 chr19:33105743 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.86 9.0 0.63 3.29e-15 Mean platelet volume; TGCT cis rs9549260 0.620 rs9532580 chr13:41244260 T/C cg21288729 chr13:41239152 FOXO1 0.78 6.18 0.49 8.64e-9 Red blood cell count; TGCT cis rs6582630 0.519 rs4002438 chr12:38484880 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs12477438 0.501 rs6708878 chr2:99801564 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs11190604 1.000 rs12354411 chr10:102294537 G/A cg16342193 chr10:102329863 NA -0.41 -5.37 -0.43 3.78e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs453301 0.686 rs28482034 chr8:8869664 G/A cg06636001 chr8:8085503 FLJ10661 -0.68 -5.63 -0.45 1.13e-7 Joint mobility (Beighton score); TGCT cis rs9389248 0.690 rs2072826 chr6:135253558 G/C cg22676075 chr6:135203613 NA -0.51 -5.11 -0.42 1.17e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs7666738 0.576 rs7660951 chr4:98651581 T/A cg17366294 chr4:99064904 C4orf37 0.57 5.29 0.43 5.46e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10791323 0.628 rs10750543 chr11:133718467 G/A cg03690763 chr11:133734501 NA -0.32 -4.78 -0.39 4.78e-6 Childhood ear infection; TGCT trans rs2727020 0.688 rs4929894 chr11:49196333 G/C cg03929089 chr4:120376271 NA -0.74 -8.38 -0.6 9.81e-14 Coronary artery disease; TGCT cis rs6952808 0.929 rs34145223 chr7:1926237 G/A cg04267008 chr7:1944627 MAD1L1 -0.36 -4.82 -0.4 4.03e-6 Bipolar disorder and schizophrenia; TGCT cis rs4665809 0.887 rs6546716 chr2:26263836 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.22 -0.49 7.14e-9 Gut microbiome composition (summer); TGCT cis rs17376456 0.877 rs12716456 chr5:93397557 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs3784262 0.692 rs4646581 chr15:58307898 C/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.83e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2692947 0.537 rs12471472 chr2:96205455 G/A cg23100626 chr2:96804247 ASTL 0.45 5.34 0.43 4.21e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs208520 0.661 rs7740835 chr6:66865548 G/A cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs7666738 0.830 rs7664051 chr4:98766970 C/G cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.748 rs115651241 chr4:119363509 C/T cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs1005277 0.579 rs2505196 chr10:38393563 G/A cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs250677 0.958 rs17109282 chr5:148416677 A/G cg18129178 chr5:148520854 ABLIM3 0.39 5.34 0.43 4.31e-7 Breast cancer; TGCT cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs7017914 0.967 rs34905858 chr8:71659450 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs68170813 0.523 rs12532447 chr7:106940476 C/T cg02696742 chr7:106810147 HBP1 -0.72 -6.05 -0.48 1.56e-8 Coronary artery disease; TGCT cis rs763014 0.865 rs4006748 chr16:632225 T/C cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs2239547 0.563 rs9876403 chr3:52916916 C/T cg10802521 chr3:52805072 NEK4 -0.59 -5.71 -0.46 7.92e-8 Schizophrenia; TGCT cis rs7618915 0.547 rs11714419 chr3:52628816 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.98 0.47 2.27e-8 Bipolar disorder; TGCT cis rs4803468 0.967 rs16975238 chr19:41944985 T/A cg09537434 chr19:41945824 ATP5SL 0.92 10.44 0.68 1.1e-18 Height; TGCT cis rs501916 1.000 rs565627 chr15:48056735 A/C cg16110827 chr15:48056943 SEMA6D -0.17 -5.12 -0.42 1.12e-6 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs4478037 0.749 rs9681623 chr3:33131375 G/T cg19404215 chr3:33155277 CRTAP 1.05 6.36 0.5 3.52e-9 Major depressive disorder; TGCT cis rs4689388 0.819 rs12649341 chr4:6294759 G/A cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg24549020 chr5:56110836 MAP3K1 -0.7 -5.01 -0.41 1.81e-6 Initial pursuit acceleration; TGCT cis rs769267 0.965 rs2074299 chr19:19380646 T/C cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs2404602 0.716 rs67920045 chr15:76800084 G/A cg26408565 chr15:76604113 ETFA -0.36 -4.75 -0.39 5.56e-6 Blood metabolite levels; TGCT cis rs12200560 0.505 rs9400166 chr6:97077101 G/A cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs4478858 0.735 rs4531329 chr1:31817810 A/T cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs7209700 0.547 rs16941780 chr17:45343183 A/G cg21624342 chr17:45890973 OSBPL7 0.19 4.77 0.39 5.02e-6 IgG glycosylation; TGCT cis rs9911578 1.000 rs4372750 chr17:57013803 A/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.21 -0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT trans rs547116 0.930 rs573900 chr9:113642363 C/T cg18410444 chr5:89825535 LYSMD3 0.65 6.71 0.52 6.25e-10 Eosinophil counts; TGCT cis rs9326248 0.581 rs7106437 chr11:116992076 T/C cg20608306 chr11:116969690 SIK3 0.39 4.6 0.38 1.04e-5 Blood protein levels; TGCT cis rs9393777 0.513 rs11967852 chr6:26612870 G/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.59 -5.14 -0.42 1.04e-6 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.891 rs2281231 chr16:1601879 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.31 -5.57 -0.45 1.52e-7 Coronary artery disease; TGCT cis rs7772486 0.840 rs11155451 chr6:146422524 A/G cg05347473 chr6:146136440 FBXO30 0.54 5.11 0.42 1.18e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.584 rs12095247 chr1:53193796 A/C cg01802117 chr1:53393560 SCP2 0.41 4.81 0.4 4.24e-6 Monocyte count; TGCT cis rs7914558 0.966 rs11191471 chr10:104702050 T/A cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs908922 0.676 rs4112786 chr1:152532872 T/A cg20991723 chr1:152506922 NA 0.44 5.97 0.47 2.29e-8 Hair morphology; TGCT cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg10802521 chr3:52805072 NEK4 -0.64 -7.66 -0.57 4.56e-12 Electroencephalogram traits; TGCT cis rs617219 0.726 rs1962002 chr5:78430689 T/C cg09550809 chr5:78407562 BHMT 0.4 5.51 0.44 2.01e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg07424592 chr7:64974309 NA 1.33 7.99 0.58 7.81e-13 Diabetic kidney disease; TGCT cis rs763014 0.931 rs1981483 chr16:630665 G/A cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs11924390 0.749 rs822363 chr3:186452991 C/G cg12454167 chr3:186435060 KNG1 0.44 6.91 0.53 2.24e-10 Adiponectin levels; TGCT cis rs4862750 0.874 rs6822062 chr4:187895553 T/C cg10295955 chr4:187884368 NA -1.02 -15.6 -0.81 5.02e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs611744 0.604 rs13248461 chr8:109285833 C/T cg21045802 chr8:109455806 TTC35 0.71 7.33 0.55 2.63e-11 Dupuytren's disease; TGCT cis rs10751667 0.643 rs7942693 chr11:957832 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs57590327 0.716 rs56106807 chr3:81765270 A/G cg07356753 chr3:81810745 GBE1 -0.75 -6.84 -0.52 3.21e-10 Extraversion; TGCT cis rs34779708 0.931 rs11596502 chr10:35387187 A/C cg03585969 chr10:35415529 CREM 0.42 4.62 0.38 9.42e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs9512730 0.906 rs4771136 chr13:28070769 C/G cg22138327 chr13:27999177 GTF3A 0.78 5.13 0.42 1.1e-6 Schizophrenia; TGCT cis rs4776059 0.876 rs2414163 chr15:52897478 T/C cg25063058 chr15:52860530 ARPP19 0.53 4.79 0.4 4.59e-6 Schizophrenia; TGCT cis rs9952991 0.941 rs2847280 chr18:12779342 A/G cg09945482 chr18:12777974 NA 0.51 4.86 0.4 3.47e-6 Inflammatory skin disease; TGCT cis rs3806843 0.576 rs246003 chr5:140340865 C/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs12541335 0.639 rs35068739 chr8:22201719 T/C cg02463440 chr8:22132932 PIWIL2 0.26 5.2 0.42 7.96e-7 Hypertriglyceridemia; TGCT cis rs10507380 0.824 rs9512622 chr13:27904178 C/T cg25543773 chr13:27185723 WASF3 0.31 4.49 0.37 1.6e-5 Electrocardiographic traits; TGCT cis rs28595532 0.920 rs116023344 chr4:119760263 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg24846343 chr22:24311635 DDTL 0.23 5.79 0.46 5.54e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2228479 0.850 rs11641552 chr16:89838700 C/A cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs4325129 0.871 rs4656827 chr1:159460032 A/G cg07417683 chr1:159440267 NA -0.39 -4.68 -0.39 7.51e-6 Obesity-related traits; TGCT cis rs7223966 1.000 rs6504173 chr17:61735056 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 4.96 0.41 2.3e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1552244 0.554 rs4488814 chr3:10002400 C/T cg00149659 chr3:10157352 C3orf10 -0.63 -4.67 -0.39 7.66e-6 Alzheimer's disease; TGCT cis rs2153535 0.580 rs4587214 chr6:8454119 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.7 0.46 8.31e-8 Motion sickness; TGCT cis rs11677370 0.561 rs12986995 chr2:3826965 G/A cg17052675 chr2:3827356 NA -0.43 -7.81 -0.57 2.04e-12 Type 2 diabetes; TGCT cis rs4654899 0.865 rs12406144 chr1:21347228 A/C cg01072550 chr1:21505969 NA -0.46 -6.95 -0.53 1.88e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6964587 0.626 rs9008 chr7:91502407 C/G cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs2404602 1.000 rs2404740 chr15:76852143 C/T cg26408565 chr15:76604113 ETFA -0.45 -5.75 -0.46 6.55e-8 Blood metabolite levels; TGCT cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg17971929 chr21:40555470 PSMG1 -0.67 -5.89 -0.47 3.39e-8 Cognitive function; TGCT cis rs67311347 1.000 rs11714912 chr3:40494065 A/G cg13683864 chr3:40499215 RPL14 0.86 5.85 0.47 4.01e-8 Renal cell carcinoma; TGCT cis rs6840360 0.533 rs13139327 chr4:152728590 A/C cg22705602 chr4:152727874 NA -0.36 -6.51 -0.5 1.69e-9 Intelligence (multi-trait analysis); TGCT cis rs9581857 0.579 rs1759861 chr13:27996406 A/C cg22138327 chr13:27999177 GTF3A -0.81 -5.85 -0.46 4.17e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs10782582 0.586 rs1796813 chr1:76400403 G/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.55 4.7 0.39 6.75e-6 Daytime sleep phenotypes; TGCT cis rs636291 0.517 rs55935829 chr1:10540926 A/T cg17425144 chr1:10567563 PEX14 0.53 7.51 0.56 1e-11 Prostate cancer; TGCT trans rs7726839 0.540 rs72703087 chr5:598029 C/T cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs7666738 0.830 rs13138438 chr4:99050545 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 1.000 rs9862534 chr3:49598064 A/G cg05785598 chr3:49045655 WDR6 0.36 4.5 0.37 1.55e-5 Menarche (age at onset); TGCT cis rs9611565 0.921 rs8137373 chr22:41729216 A/G cg03806693 chr22:41940476 POLR3H 0.97 10.25 0.68 3.06e-18 Vitiligo; TGCT cis rs7412746 0.634 rs12096831 chr1:150864113 T/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.81 0.4 4.33e-6 Melanoma; TGCT cis rs9457247 0.602 rs2239827 chr6:167490945 G/A cg07741184 chr6:167504864 NA 0.24 4.7 0.39 6.89e-6 Crohn's disease; TGCT cis rs12220238 0.778 rs10824216 chr10:76409210 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.59 4.55 0.38 1.25e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4722166 0.630 rs13311199 chr7:22789793 A/C cg26061582 chr7:22766209 IL6 0.57 7.17 0.54 5.91e-11 Lung cancer; TGCT cis rs9733 0.596 rs72702536 chr1:150662574 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.11 0.42 1.2e-6 Tonsillectomy; TGCT cis rs3796352 1.000 rs13076033 chr3:52898427 T/C cg15956490 chr3:53032818 SFMBT1 0.57 4.89 0.4 3.01e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9399135 0.967 rs7741626 chr6:135314182 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs4665809 0.941 rs6735145 chr2:26270302 T/C cg25036284 chr2:26402008 FAM59B -0.55 -4.71 -0.39 6.4e-6 Gut microbiome composition (summer); TGCT cis rs1153858 1.000 rs7167900 chr15:45639471 A/G cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs7523273 0.505 rs34277355 chr1:207881491 C/A cg22525895 chr1:207977042 MIR29B2 0.29 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs2456568 0.802 rs1506656 chr11:93639813 G/A cg14065697 chr11:93583672 C11orf90 -0.36 -4.45 -0.37 1.86e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7666738 0.830 rs12233741 chr4:98950296 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT trans rs6089829 0.962 rs2277768 chr20:61666823 T/C cg13615516 chr5:77269221 NA 0.66 8.29 0.6 1.56e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs7659604 0.539 rs7686084 chr4:122764725 A/C cg06713675 chr4:122721982 EXOSC9 -0.68 -9.18 -0.64 1.23e-15 Type 2 diabetes; TGCT cis rs7267979 1.000 rs2257982 chr20:25269630 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611519 0.964 rs4820428 chr22:41537589 C/T cg03806693 chr22:41940476 POLR3H 0.67 6.2 0.49 7.87e-9 Neuroticism; TGCT cis rs1062177 0.724 rs2964590 chr5:151118146 C/G cg00977110 chr5:151150581 G3BP1 -0.4 -4.67 -0.39 7.7e-6 Preschool internalizing problems; TGCT cis rs1799949 1.000 rs4793229 chr17:41418334 C/T cg05368731 chr17:41323189 NBR1 -1.2 -14.2 -0.79 8.98e-28 Menopause (age at onset); TGCT cis rs151997 0.671 rs493507 chr5:50219675 G/T cg06027927 chr5:50259733 NA -0.56 -5.64 -0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs9527 0.569 rs10883801 chr10:104677887 A/C cg04362960 chr10:104952993 NT5C2 0.64 5.4 0.44 3.33e-7 Arsenic metabolism; TGCT cis rs1008375 0.932 rs6844593 chr4:17659039 T/C cg16339924 chr4:17578868 LAP3 0.66 5.52 0.44 1.89e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7582180 0.629 rs13010911 chr2:100953390 G/C cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs858239 0.699 rs955187 chr7:23194605 A/G cg05602783 chr7:23145260 KLHL7 0.64 5.44 0.44 2.77e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs12497850 0.931 rs7431710 chr3:48935583 G/A cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs6088590 1.000 rs55753039 chr20:33394940 C/T cg06115741 chr20:33292138 TP53INP2 0.65 5.48 0.44 2.28e-7 Coronary artery disease; TGCT cis rs4727027 0.901 rs4727018 chr7:148822247 G/C cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2273156 1.000 rs7141292 chr14:35462906 T/A cg15394648 chr14:35761551 PSMA6 -0.6 -4.44 -0.37 1.94e-5 Immunoglobulin light chain (AL) amyloidosis; TGCT cis rs8017423 0.900 rs7141887 chr14:90705364 G/T cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg23131131 chr22:24373011 LOC391322 0.81 8.72 0.62 1.53e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs651907 0.557 rs13099674 chr3:101489629 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.53 5.02 0.41 1.77e-6 Colorectal cancer; TGCT cis rs10791097 0.694 rs11222369 chr11:130744670 A/G cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs6089829 0.888 rs4809467 chr20:61671688 A/G cg17470723 chr8:74884337 TCEB1 0.78 6.83 0.52 3.42e-10 Prostate cancer (SNP x SNP interaction); TGCT trans rs10203711 1.000 rs6713610 chr2:239566874 C/A cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs13424612 0.930 rs12478169 chr2:240951603 C/T cg26363272 chr2:240904871 NDUFA10 0.28 4.77 0.39 5.18e-6 Odorant perception (isobutyraldehyde); TGCT cis rs2276314 0.857 rs9304155 chr18:33585710 A/C cg19628046 chr18:33552617 C18orf21 0.52 4.49 0.37 1.64e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs868036 0.634 rs8028313 chr15:68043057 C/G cg05925327 chr15:68127851 NA -0.51 -4.97 -0.41 2.2e-6 Restless legs syndrome; TGCT cis rs6570726 0.791 rs418701 chr6:145889992 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 1.000 rs112847840 chr3:10101652 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs2535633 0.631 rs2581827 chr3:52966558 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.54 4.94 0.41 2.49e-6 Body mass index; TGCT cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT trans rs941408 1.000 rs1736179 chr19:2795516 T/A cg22153745 chr1:153894579 GATAD2B -0.64 -7.22 -0.54 4.49e-11 Total cholesterol levels; TGCT cis rs4820539 1.000 rs756631 chr22:23463183 A/G cg14186256 chr22:23484241 RTDR1 0.97 11.78 0.73 5.73e-22 Bone mineral density; TGCT cis rs6921919 0.583 rs9468354 chr6:28337801 T/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.37 -0.43 3.8e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs933688 0.532 rs13165085 chr5:90538448 G/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.54 -4.82 -0.4 4.09e-6 Smoking behavior; TGCT cis rs17253792 0.822 rs17832371 chr14:56162302 C/A cg01858014 chr14:56050164 KTN1 -0.35 -4.47 -0.37 1.73e-5 Putamen volume; TGCT cis rs2933343 0.700 rs1683779 chr3:128642048 A/G cg11901034 chr3:128598214 ACAD9 -0.65 -6.08 -0.48 1.37e-8 IgG glycosylation; TGCT cis rs9811920 0.965 rs9837131 chr3:99854514 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.42 -4.79 -0.4 4.67e-6 Axial length; TGCT cis rs2204008 0.515 rs11495471 chr12:38027178 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.24 0.43 6.68e-7 Bladder cancer; TGCT cis rs1215050 0.791 rs1669745 chr4:98842047 G/A cg17366294 chr4:99064904 C4orf37 -0.57 -6.13 -0.48 1.08e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.73 0.57 3.23e-12 Platelet count; TGCT cis rs4849845 0.598 rs3889223 chr2:121024432 A/G cg24070213 chr2:121070622 NA 0.35 4.8 0.4 4.43e-6 Mean platelet volume; TGCT cis rs2455799 0.573 rs2455830 chr3:15749213 C/T cg16303742 chr3:15540471 COLQ -0.26 -4.91 -0.4 2.82e-6 Mean platelet volume; TGCT cis rs6088580 0.634 rs6088512 chr20:33095891 G/A cg08999081 chr20:33150536 PIGU 0.28 5.56 0.45 1.61e-7 Glomerular filtration rate (creatinine); TGCT cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg18252515 chr7:66147081 NA -1.1 -7.22 -0.54 4.49e-11 Diabetic kidney disease; TGCT cis rs2836974 0.830 rs2735309 chr21:40715313 C/T cg17971929 chr21:40555470 PSMG1 0.91 7.93 0.58 1.07e-12 Cognitive function; TGCT cis rs763121 1.000 rs763121 chr22:38879940 C/T cg06022373 chr22:39101656 GTPBP1 -0.67 -6.37 -0.5 3.4e-9 Menopause (age at onset); TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg13397359 chr6:42928475 GNMT 0.66 5.81 0.46 4.9e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs17030434 0.769 rs11727144 chr4:154645181 G/C cg14289246 chr4:154710475 SFRP2 -0.79 -5.85 -0.47 4.04e-8 Electrocardiographic conduction measures; TGCT cis rs10751667 0.666 rs6597957 chr11:982294 T/A cg06064525 chr11:970664 AP2A2 -0.35 -7.89 -0.58 1.39e-12 Alzheimer's disease (late onset); TGCT cis rs700651 0.752 rs7592556 chr2:198891021 G/A cg00792783 chr2:198669748 PLCL1 0.59 5.19 0.42 8.27e-7 Intracranial aneurysm; TGCT cis rs9291683 0.588 rs2240722 chr4:10020757 A/G cg11266682 chr4:10021025 SLC2A9 0.69 10.28 0.68 2.66e-18 Bone mineral density; TGCT cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7312933 0.558 rs11181463 chr12:42763636 C/T cg19980929 chr12:42632907 YAF2 0.43 6.14 0.48 1.05e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs73001065 0.536 rs10408596 chr19:19512657 A/T cg03709012 chr19:19516395 GATAD2A 0.88 4.69 0.39 7.11e-6 LDL cholesterol; TGCT cis rs7178572 0.568 rs11632941 chr15:77533888 A/G cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 -0.52 -5.59 -0.45 1.35e-7 Lymphocyte counts; TGCT cis rs2455799 0.559 rs6781202 chr3:15905881 T/C cg12172478 chr3:16357591 RFTN1 -0.34 -5.14 -0.42 1.02e-6 Mean platelet volume; TGCT cis rs2153535 0.580 rs6929206 chr6:8447961 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs68092024 0.731 rs792840 chr3:99471251 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.49 -5.99 -0.47 2.1e-8 Cleft lip with or without cleft palate; TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg04389838 chr3:44770851 ZNF501 -0.41 -5.7 -0.46 8.13e-8 Depressive symptoms; TGCT cis rs17376456 0.877 rs7701011 chr5:93311456 G/A cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs8177253 1.000 rs8177271 chr3:133482230 G/A cg08439880 chr3:133502540 NA -0.31 -5.87 -0.47 3.69e-8 Iron status biomarkers; TGCT cis rs2204008 0.570 rs1315664 chr12:38138274 A/G cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs453301 0.653 rs7005133 chr8:8901222 T/G cg06636001 chr8:8085503 FLJ10661 0.85 7.69 0.57 3.95e-12 Joint mobility (Beighton score); TGCT cis rs4478858 0.663 rs11591060 chr1:31780012 G/A cg00250761 chr1:31883323 NA -0.27 -4.94 -0.41 2.43e-6 Alcohol dependence; TGCT cis rs2996428 0.667 rs113120570 chr1:3770450 G/C cg13057898 chr1:3703894 LRRC47 0.21 4.64 0.38 8.81e-6 Red cell distribution width; TGCT cis rs6582630 0.555 rs10880421 chr12:38423015 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.94 0.41 2.52e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs896854 0.846 rs2340584 chr8:95916811 A/G cg16049864 chr8:95962084 TP53INP1 -0.71 -9.79 -0.66 4.08e-17 Type 2 diabetes; TGCT cis rs7621025 0.599 rs13063987 chr3:136445397 C/G cg15507776 chr3:136538369 TMEM22 -0.51 -4.65 -0.39 8.23e-6 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs1552244 0.882 rs56125067 chr3:9984130 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.25 -0.49 6.15e-9 Alzheimer's disease; TGCT cis rs1682361 1 rs1682361 chr3:136734014 G/C cg12473912 chr3:136751656 NA 0.54 10.13 0.67 6.21e-18 Schizophrenia; TGCT cis rs1568889 1.000 rs10767693 chr11:28093926 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.13 0.71 2.27e-20 Bipolar disorder; TGCT cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg07507251 chr3:52567010 NT5DC2 -0.46 -6.67 -0.51 7.5e-10 Bipolar disorder; TGCT cis rs8077577 0.836 rs11652964 chr17:18040404 C/T cg09161412 chr17:18057145 MYO15A -0.71 -5.67 -0.45 9.44e-8 Obesity-related traits; TGCT cis rs7172809 0.897 rs78412727 chr15:77827185 A/G cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs2204008 0.660 rs2320745 chr12:38239101 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.18 0.54 5.51e-11 Bladder cancer; TGCT cis rs1008375 0.898 rs7678654 chr4:17575376 T/G cg18681998 chr4:17616180 MED28 0.92 9.32 0.64 5.46e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs796364 0.715 rs77089299 chr2:201116853 A/G cg17644776 chr2:200775616 C2orf69 -0.37 -5.05 -0.41 1.53e-6 Schizophrenia; TGCT cis rs4654899 0.772 rs61778530 chr1:21087363 G/C cg01072550 chr1:21505969 NA -0.48 -7.17 -0.54 6.05e-11 Superior frontal gyrus grey matter volume; TGCT cis rs12479064 0.724 rs62153852 chr2:99934713 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -4.54 -0.38 1.31e-5 Chronic sinus infection; TGCT cis rs2239815 0.515 rs5752810 chr22:29225523 G/A cg02153584 chr22:29168773 CCDC117 0.75 5.04 0.41 1.6e-6 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs7973719 0.769 rs61917956 chr12:7348659 T/C cg07052231 chr12:7363540 PEX5 0.36 5.6 0.45 1.31e-7 IgG glycosylation; TGCT cis rs17376456 0.825 rs55724660 chr5:93276636 A/G cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs7267979 0.966 rs4813557 chr20:25292545 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1552244 1.000 rs35741213 chr3:10087661 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs4819052 0.765 rs2838827 chr21:46656146 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.76 0.39 5.4e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6540559 0.546 rs57315825 chr1:210030197 C/T cg21951975 chr1:209979733 IRF6 0.74 5.8 0.46 5.11e-8 Cleft lip with or without cleft palate; TGCT cis rs57590327 0.503 rs12152272 chr3:81911684 G/A cg07356753 chr3:81810745 GBE1 -0.69 -6.34 -0.49 3.87e-9 Extraversion; TGCT cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg23758822 chr17:41437982 NA 0.75 7.03 0.53 1.22e-10 Menopause (age at onset); TGCT cis rs6121246 0.529 rs56153385 chr20:30187609 C/T cg18721089 chr20:30220636 NA -0.57 -6.22 -0.49 6.83e-9 Mean corpuscular hemoglobin; TGCT cis rs2639990 1.000 rs609303 chr18:72895242 C/T cg21330207 chr18:72916311 ZADH2 0.51 4.57 0.38 1.16e-5 Vascular endothelial growth factor levels; TGCT cis rs2046867 0.862 rs11920131 chr3:72858630 C/G cg25664220 chr3:72788482 NA -0.53 -6.72 -0.52 5.89e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs67478160 0.619 rs12437066 chr14:104236844 A/C cg26031613 chr14:104095156 KLC1 -0.63 -6.38 -0.5 3.18e-9 Schizophrenia; TGCT cis rs61931739 0.534 rs11053131 chr12:34282109 A/G cg06521331 chr12:34319734 NA -0.34 -5.54 -0.45 1.75e-7 Morning vs. evening chronotype; TGCT cis rs1552244 0.572 rs3843008 chr3:10173742 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.96 5.77 0.46 5.88e-8 Alzheimer's disease; TGCT cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.19 -0.54 5.48e-11 Prostate cancer; TGCT cis rs1552244 0.882 rs13089863 chr3:10032259 G/T cg02579736 chr3:10068473 FANCD2;CIDECP -0.85 -5.86 -0.47 3.98e-8 Alzheimer's disease; TGCT cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg13395646 chr4:1353034 KIAA1530 -0.42 -5.1 -0.42 1.22e-6 Longevity; TGCT cis rs7178572 0.568 rs12911371 chr15:77689050 C/T cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg02187348 chr16:89574699 SPG7 -0.66 -7.47 -0.56 1.27e-11 Multiple myeloma (IgH translocation); TGCT cis rs3749237 0.964 rs62260719 chr3:49852419 G/A cg03060546 chr3:49711283 APEH 0.69 7.05 0.53 1.12e-10 Resting heart rate; TGCT cis rs7666738 0.830 rs17550630 chr4:99008332 G/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.798 rs6736064 chr2:99658201 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs6089829 0.962 rs3899032 chr20:61658542 G/A cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs67311347 1.000 rs4973878 chr3:40407565 C/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs4563143 0.514 rs112651366 chr19:29299704 A/T cg04546413 chr19:29218101 NA 0.74 5.41 0.44 3.16e-7 Methadone dose in opioid dependence; TGCT cis rs6998277 0.830 rs965661 chr8:103597586 C/T cg10187029 chr8:103597600 NA 0.56 8.83 0.62 8.12e-15 Migraine; TGCT cis rs6582630 0.622 rs11182005 chr12:38441292 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6570726 0.791 rs9403730 chr6:145907233 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1994135 0.617 rs10844642 chr12:33730368 A/C cg06521331 chr12:34319734 NA -0.31 -4.86 -0.4 3.5e-6 Resting heart rate; TGCT cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg03188948 chr7:1209495 NA 0.46 6.43 0.5 2.46e-9 Longevity;Endometriosis; TGCT cis rs919433 0.679 rs10931787 chr2:198520615 A/G cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs10789285 0.650 rs2245318 chr1:69690618 G/A ch.1.69469992R chr1:69697404 NA 0.31 4.54 0.38 1.32e-5 Psoriasis; TGCT cis rs1552244 0.706 rs3901800 chr3:9976864 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.41 -5.77 -0.46 5.97e-8 Alzheimer's disease; TGCT cis rs3820068 0.603 rs72647118 chr1:15956535 G/T cg05660106 chr1:15850417 CASP9 0.84 8.28 0.6 1.64e-13 Systolic blood pressure; TGCT cis rs7523273 0.606 rs2281289 chr1:207978916 C/T cg22525895 chr1:207977042 MIR29B2 -0.53 -8.94 -0.63 4.6e-15 Schizophrenia; TGCT cis rs28785552 0.800 rs1971063 chr19:53232854 G/C cg22067481 chr19:53234126 ZNF611 -0.49 -7.21 -0.54 4.87e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs1075232 1.000 rs4450360 chr15:31682030 G/A cg01030201 chr15:31746330 NA -1.1 -5.4 -0.44 3.27e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs9486719 1.000 rs12190507 chr6:96898265 T/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs11122272 0.735 rs2790878 chr1:231534390 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.42 -0.5 2.62e-9 Hemoglobin concentration; TGCT cis rs13256369 0.708 rs11783670 chr8:8559394 G/A cg18904891 chr8:8559673 CLDN23 0.56 5.0 0.41 1.94e-6 Obesity-related traits; TGCT cis rs9611565 0.921 rs2143695 chr22:41728620 A/G cg13695892 chr22:41940480 POLR3H -0.7 -7.1 -0.54 8.35e-11 Vitiligo; TGCT cis rs7192750 0.583 rs8046916 chr16:72047751 C/G cg06353428 chr16:71660113 MARVELD3 -1.01 -5.21 -0.42 7.62e-7 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs67311347 0.544 rs9833640 chr3:40354941 T/A cg17264618 chr3:40429014 ENTPD3 0.3 4.48 0.37 1.69e-5 Renal cell carcinoma; TGCT cis rs4808199 0.649 rs17216693 chr19:19666574 T/C cg03709012 chr19:19516395 GATAD2A 0.9 5.63 0.45 1.12e-7 Nonalcoholic fatty liver disease; TGCT cis rs782590 0.764 rs935177 chr2:55826761 C/G cg18811423 chr2:55921094 PNPT1 0.55 5.72 0.46 7.65e-8 Metabolic syndrome; TGCT cis rs7809950 1.000 rs2253146 chr7:107200319 A/G cg23024343 chr7:107201750 COG5 -0.34 -5.26 -0.43 6.08e-7 Coronary artery disease; TGCT cis rs8180040 0.726 rs4234465 chr3:47026885 C/G cg27129171 chr3:47204927 SETD2 0.67 8.21 0.59 2.41e-13 Colorectal cancer; TGCT cis rs2836974 0.590 rs9974757 chr21:40617244 T/C cg11890956 chr21:40555474 PSMG1 -0.8 -7.89 -0.58 1.38e-12 Cognitive function; TGCT cis rs1061377 0.965 rs3733275 chr4:39122697 C/T cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs1005277 0.579 rs176838 chr10:38371899 A/T cg13531842 chr10:38383804 ZNF37A 0.4 4.45 0.37 1.92e-5 Extrinsic epigenetic age acceleration; TGCT cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg12310025 chr6:25882481 NA 0.84 8.43 0.6 7.35e-14 Blood metabolite levels; TGCT cis rs11864453 0.611 rs9926927 chr16:72130556 G/T cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs4689388 0.926 rs4416547 chr4:6293967 G/A cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4845570 0.920 rs1196456 chr1:151737349 T/A cg07092448 chr1:151763213 TDRKH 1.03 8.1 0.59 4.35e-13 Coronary artery disease; TGCT cis rs2404602 0.569 rs2469249 chr15:76772062 C/T cg22467129 chr15:76604101 ETFA 0.5 4.99 0.41 2.03e-6 Blood metabolite levels; TGCT cis rs7772486 0.754 rs6910790 chr6:146255330 G/A cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9549260 0.755 rs12585875 chr13:41199531 A/G cg21288729 chr13:41239152 FOXO1 0.97 10.16 0.67 5.23e-18 Red blood cell count; TGCT cis rs10465746 0.901 rs17534614 chr1:84383079 G/A cg10977910 chr1:84465055 TTLL7 0.64 6.32 0.49 4.38e-9 Obesity-related traits; TGCT cis rs1577917 0.740 rs2758845 chr6:86334848 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.52 -4.76 -0.39 5.23e-6 Response to antipsychotic treatment; TGCT cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs6725041 0.819 rs13429136 chr2:213092176 T/C cg20637307 chr2:213403960 ERBB4 -0.51 -4.49 -0.37 1.64e-5 QT interval (ambient particulate matter interaction); TGCT cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg00684032 chr4:1343700 KIAA1530 0.22 4.85 0.4 3.69e-6 Obesity-related traits; TGCT cis rs644799 1.000 rs651445 chr11:95539122 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg08736216 chr1:53307985 ZYG11A -0.29 -5.6 -0.45 1.33e-7 Monocyte count; TGCT cis rs4664308 0.935 rs4520994 chr2:160937750 G/A cg03641300 chr2:160917029 PLA2R1 -0.28 -6.83 -0.52 3.43e-10 Idiopathic membranous nephropathy; TGCT cis rs9653442 0.527 rs4851258 chr2:100780830 T/C cg07810366 chr2:100720526 AFF3 -0.36 -5.26 -0.43 6.14e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3733585 0.699 rs7686538 chr4:9948077 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.42 -0.55 1.62e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6582630 0.519 rs11514056 chr12:38284001 G/T cg26384229 chr12:38710491 ALG10B 0.84 7.33 0.55 2.58e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs6831352 0.918 rs2851247 chr4:100046091 C/G cg12011299 chr4:100065546 ADH4 -0.44 -5.08 -0.41 1.37e-6 Alcohol dependence; TGCT cis rs12579753 0.917 rs2401003 chr12:82215192 G/A cg07988820 chr12:82153109 PPFIA2 -0.58 -6.06 -0.48 1.52e-8 Resting heart rate; TGCT cis rs1903068 0.853 rs12498317 chr4:56007093 G/A cg16572876 chr4:56024045 NA 0.46 5.03 0.41 1.65e-6 Endometriosis; TGCT cis rs2404602 0.735 rs1607015 chr15:76702429 C/T cg26408565 chr15:76604113 ETFA 0.38 4.49 0.37 1.58e-5 Blood metabolite levels; TGCT cis rs3617 0.503 rs9866243 chr3:52915219 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.83 0.4 3.91e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3847687 1.000 rs3847687 chr12:131525053 C/T cg13586425 chr12:131519906 GPR133 -0.33 -5.26 -0.43 6.17e-7 Longevity; TGCT cis rs6754311 0.731 rs7579771 chr2:136580260 T/A cg07169764 chr2:136633963 MCM6 0.65 6.1 0.48 1.27e-8 Mosquito bite size; TGCT cis rs6460942 0.915 rs2216050 chr7:12304073 T/C cg06484146 chr7:12443880 VWDE -0.42 -4.54 -0.38 1.31e-5 Coronary artery disease; TGCT trans rs916888 0.610 rs199452 chr17:44801340 C/T cg22433210 chr17:43662623 NA 0.94 8.08 0.59 4.8e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs40363 0.951 rs250632 chr16:3523047 C/T cg05754148 chr16:3507555 NAT15 0.46 4.67 0.39 7.61e-6 Tuberculosis; TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs174479 0.677 rs1000778 chr11:61655305 A/G cg19610905 chr11:61596333 FADS2 0.61 5.21 0.42 7.77e-7 Sphingolipid levels; TGCT cis rs4689388 0.926 rs28420833 chr4:6279504 G/A cg00701064 chr4:6280414 WFS1 0.45 6.19 0.49 8e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs137603 0.562 rs137644 chr22:39728139 A/G cg01093212 chr22:39715156 SNORD43;RPL3 -0.49 -4.74 -0.39 5.78e-6 Primary biliary cholangitis; TGCT trans rs459571 0.839 rs2519831 chr9:136886257 T/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.72 -7.78 -0.57 2.37e-12 Platelet distribution width; TGCT cis rs11577318 0.853 rs7541333 chr1:26622889 C/T cg12733254 chr1:26682999 NA -0.21 -4.82 -0.4 4.04e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6540559 0.673 rs6698154 chr1:210007777 A/G cg23283495 chr1:209979779 IRF6 0.6 4.5 0.37 1.54e-5 Cleft lip with or without cleft palate; TGCT cis rs7226408 0.857 rs2034215 chr18:34529163 A/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2361718 0.500 rs4889970 chr17:78096086 C/T cg02096758 chr17:77394895 HRNBP3 -0.25 -4.71 -0.39 6.59e-6 Yeast infection; TGCT cis rs9858542 0.903 rs11921590 chr3:49644193 T/C cg03060546 chr3:49711283 APEH -0.63 -5.48 -0.44 2.28e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs597539 0.652 rs627731 chr11:68698663 A/C cg06028808 chr11:68637592 NA 0.53 6.86 0.52 2.89e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7819412 0.522 rs13266785 chr8:10989521 G/A cg21775007 chr8:11205619 TDH -0.6 -5.27 -0.43 5.9e-7 Triglycerides; TGCT cis rs6964587 1.000 rs11982213 chr7:91722966 A/G cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs4654899 0.733 rs10916907 chr1:21261088 A/C cg01072550 chr1:21505969 NA -0.56 -9.04 -0.63 2.64e-15 Superior frontal gyrus grey matter volume; TGCT cis rs12908161 1.000 rs62019469 chr15:85321220 T/C cg17173187 chr15:85201210 NMB 0.57 6.4 0.5 2.89e-9 Schizophrenia; TGCT cis rs7086627 0.515 rs10887896 chr10:82210144 A/C cg01528321 chr10:82214614 TSPAN14 0.65 6.2 0.49 7.78e-9 Post bronchodilator FEV1; TGCT cis rs3812049 0.826 rs6860245 chr5:127367998 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.6 -5.5 -0.44 2.11e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs9914544 0.545 rs2892015 chr17:18786849 C/T cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs453301 0.686 rs3895823 chr8:8873646 T/C cg00184457 chr8:8946301 NA -0.27 -4.92 -0.4 2.72e-6 Joint mobility (Beighton score); TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs10197940 0.662 rs1047957 chr2:152333773 C/T cg19508488 chr2:152266495 RIF1 0.74 6.66 0.51 7.77e-10 Lung cancer; TGCT cis rs1692580 0.807 rs60635488 chr1:2202572 C/T cg24578937 chr1:2090814 PRKCZ 0.21 4.6 0.38 1.01e-5 Coronary artery disease; TGCT cis rs9650657 0.836 rs891556 chr8:10623633 G/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.44 -0.37 1.97e-5 Neuroticism; TGCT cis rs13202913 0.837 rs6906667 chr6:151772569 A/G cg03627880 chr6:151815985 C6orf97 -0.74 -5.47 -0.44 2.35e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs11167764 0.895 rs13189044 chr5:141471431 A/C cg08523384 chr5:141488047 NDFIP1 -0.25 -5.11 -0.42 1.2e-6 Crohn's disease; TGCT cis rs78707713 0.560 rs17569412 chr10:71237536 C/A cg14388049 chr10:71211838 TSPAN15 -0.39 -4.64 -0.38 8.84e-6 Venous thromboembolism; TGCT cis rs12136530 0.577 rs4481878 chr1:19791086 C/A cg03884082 chr1:19971709 NBL1 -0.43 -4.51 -0.38 1.5e-5 Lead levels in blood; TGCT cis rs854765 0.693 rs4924823 chr17:17764502 A/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.8 -0.4 4.56e-6 Total body bone mineral density; TGCT cis rs362296 0.698 rs3095072 chr4:3263325 G/A cg06533319 chr4:3265114 C4orf44 0.23 4.64 0.38 8.87e-6 Parental longevity (mother's age at death); TGCT cis rs7611238 0.560 rs9826999 chr3:195118896 T/A cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.81e-6 Body mass index; TGCT cis rs433598 0.894 rs395501 chr16:20683296 C/T cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -5.09 -0.42 1.31e-6 Schizophrenia; TGCT cis rs1005277 0.505 rs719569 chr10:38154415 T/G cg25427524 chr10:38739819 LOC399744 0.37 7.61 0.56 5.93e-12 Extrinsic epigenetic age acceleration; TGCT cis rs9611565 0.879 rs4820437 chr22:41761290 T/C cg06634786 chr22:41940651 POLR3H -0.8 -7.65 -0.57 4.81e-12 Vitiligo; TGCT cis rs9549367 0.707 rs9549353 chr13:113843427 G/A cg18105134 chr13:113819100 PROZ -0.46 -8.3 -0.6 1.46e-13 Platelet distribution width; TGCT cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg03396347 chr1:1875803 NA -0.38 -6.89 -0.53 2.48e-10 Body mass index; TGCT cis rs2842992 0.789 rs3818300 chr6:160201677 G/A cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs10791097 0.694 rs2236717 chr11:130739887 G/T cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11785400 0.793 rs4581034 chr8:143736968 G/A cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.31e-7 Schizophrenia; TGCT cis rs28785552 0.536 rs7260576 chr19:53248626 G/T cg10871876 chr19:53194124 ZNF83 0.47 5.9 0.47 3.24e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7178572 1.000 rs12910361 chr15:77782335 A/G cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs6570726 0.935 rs398060 chr6:145841515 C/T cg23711669 chr6:146136114 FBXO30 -0.67 -5.93 -0.47 2.75e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs34192067 chr7:65887657 C/A cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs1153858 1.000 rs1145085 chr15:45657804 A/G cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs6582630 0.532 rs1589394 chr12:38419700 A/C cg26384229 chr12:38710491 ALG10B 0.62 5.61 0.45 1.23e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs2692947 0.509 rs79546441 chr2:96218872 C/A cg23100626 chr2:96804247 ASTL 0.41 4.71 0.39 6.59e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs854765 0.583 rs4244602 chr17:17841456 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.94 0.58 1.04e-12 Total body bone mineral density; TGCT cis rs7927592 0.763 rs4340059 chr11:68362433 A/G cg16797656 chr11:68205561 LRP5 0.25 4.5 0.37 1.53e-5 Total body bone mineral density; TGCT cis rs17152411 1.000 rs41303609 chr10:126670613 G/T cg07906193 chr10:126599966 NA 0.41 4.83 0.4 3.97e-6 Height; TGCT cis rs7666738 0.830 rs7694889 chr4:98855596 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10206020 0.797 rs72778008 chr2:1573182 T/G cg01028140 chr2:1542097 TPO -0.32 -4.99 -0.41 1.97e-6 IgG glycosylation; TGCT cis rs2346177 0.519 rs4563285 chr2:46669944 C/G cg26688816 chr2:46740690 ATP6V1E2 -0.46 -4.91 -0.4 2.86e-6 HDL cholesterol; TGCT cis rs2795502 0.882 rs2744087 chr10:43340270 A/C cg20628663 chr10:43360327 NA -0.44 -6.23 -0.49 6.74e-9 Blood protein levels; TGCT cis rs950169 0.881 rs150965 chr15:85080527 T/G cg11189052 chr15:85197271 WDR73 0.83 6.63 0.51 9.25e-10 Schizophrenia; TGCT cis rs7819412 0.668 rs920047 chr8:11087475 C/T cg21775007 chr8:11205619 TDH -0.52 -5.0 -0.41 1.92e-6 Triglycerides; TGCT cis rs6540559 0.673 rs6540564 chr1:210019910 T/C cg23283495 chr1:209979779 IRF6 0.6 4.5 0.37 1.54e-5 Cleft lip with or without cleft palate; TGCT cis rs10875595 0.779 rs1363451 chr5:140658138 G/A cg20560182 chr5:140700478 TAF7 -0.66 -5.06 -0.41 1.49e-6 Pulmonary function decline; TGCT cis rs79724016 1.000 rs56044825 chr1:42140668 C/T cg14093106 chr1:42503579 NA -0.64 -4.5 -0.37 1.53e-5 Breast cancer; TGCT cis rs3809566 0.710 rs4075583 chr15:63340227 C/T cg08198488 chr15:63333792 TPM1 -0.29 -4.46 -0.37 1.84e-5 Platelet count; TGCT cis rs524281 0.861 rs11607393 chr11:65875149 C/A cg00563793 chr11:65837595 PACS1 0.54 4.55 0.38 1.24e-5 Electroencephalogram traits; TGCT cis rs6666258 0.961 rs34515871 chr1:154812280 C/T cg06418219 chr1:154948305 SHC1;CKS1B 0.66 5.28 0.43 5.48e-7 Atrial fibrillation; TGCT cis rs2050392 0.894 rs303430 chr10:30706235 C/A cg13289132 chr10:30722225 MAP3K8 -0.38 -4.6 -0.38 1.03e-5 Inflammatory bowel disease; TGCT cis rs4665809 1.000 rs4665821 chr2:26309949 A/C cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs17253792 0.822 rs12100949 chr14:56040787 T/C cg01858014 chr14:56050164 KTN1 -0.36 -4.55 -0.38 1.24e-5 Putamen volume; TGCT cis rs11673344 0.504 rs6510591 chr19:37624088 A/G cg08039142 chr19:36980659 ZNF566 0.51 4.69 0.39 7.14e-6 Obesity-related traits; TGCT cis rs7726839 0.540 rs72703095 chr5:601789 T/C cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs11578119 0.933 rs6675683 chr1:170453146 C/G cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs34779708 0.931 rs4934693 chr10:35271844 G/A cg04310649 chr10:35416472 CREM -0.51 -4.54 -0.38 1.31e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs17345786 0.906 rs56171035 chr3:101111108 G/C cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs367615 1.000 rs58931051 chr5:108907732 A/G cg17395555 chr5:108820864 NA 0.29 4.6 0.38 1.04e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs875971 0.522 rs1880556 chr7:65432544 T/C cg18876405 chr7:65276391 NA 0.41 6.53 0.51 1.55e-9 Aortic root size; TGCT cis rs6964587 1.000 rs2888851 chr7:91648341 G/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs3617 0.625 rs11715347 chr3:52883070 C/T cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg20891558 chr2:74357851 NA -0.55 -6.48 -0.5 1.91e-9 Gestational age at birth (maternal effect); TGCT cis rs748404 0.660 rs542898 chr15:43719392 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs7552404 0.628 rs5745442 chr1:76342858 T/G cg03433033 chr1:76189801 ACADM 0.76 7.62 0.56 5.6e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg27535305 chr1:53392650 SCP2 -0.29 -5.59 -0.45 1.4e-7 Monocyte count; TGCT cis rs447921 0.861 rs12951513 chr17:74455069 C/T cg09812376 chr17:74270190 QRICH2 -0.46 -4.74 -0.39 5.66e-6 Mitochondrial DNA levels; TGCT cis rs7014346 0.767 rs7837706 chr8:128423184 G/C cg04263511 chr8:128962092 PVT1 -0.31 -4.5 -0.37 1.54e-5 Colorectal cancer; TGCT cis rs854765 0.624 rs9891957 chr17:17744439 G/A cg04398451 chr17:18023971 MYO15A 0.3 4.59 0.38 1.06e-5 Total body bone mineral density; TGCT cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg02187348 chr16:89574699 SPG7 0.61 6.45 0.5 2.29e-9 Multiple myeloma (IgH translocation); TGCT cis rs9527 0.590 rs2182348 chr10:104872684 A/G cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs595982 0.726 rs607356 chr19:49371241 T/C cg15549821 chr19:49342101 PLEKHA4 -0.37 -4.85 -0.4 3.68e-6 Red cell distribution width; TGCT cis rs9985766 1.000 rs9784426 chr4:151015661 A/G cg05926478 chr4:151174724 DCLK2 0.26 4.96 0.41 2.31e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs6076065 0.894 rs2243448 chr20:23378345 G/A cg11657817 chr20:23433608 CST11 0.31 5.47 0.44 2.42e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs9952991 0.941 rs2847280 chr18:12779342 A/G cg24737193 chr18:12778029 NA 0.54 6.03 0.48 1.76e-8 Inflammatory skin disease; TGCT cis rs7925523 0.891 rs2097853 chr11:61466267 G/T cg18476690 chr11:61125255 CYBASC3 0.27 4.53 0.38 1.36e-5 Plasma omega-6 polyunsaturated fatty acid levels (gamma-linolenic acid); TGCT cis rs853679 0.550 rs1237875 chr6:28173010 A/G cg12963246 chr6:28129442 ZNF389 -0.49 -4.8 -0.4 4.46e-6 Depression; TGCT cis rs7208859 0.623 rs56325146 chr17:29151024 T/C cg14008862 chr17:28927542 LRRC37B2 0.74 4.95 0.41 2.35e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg11890956 chr21:40555474 PSMG1 -0.69 -6.72 -0.52 5.89e-10 Menarche (age at onset); TGCT cis rs912057 0.671 rs1294425 chr6:6744292 G/A cg06612196 chr6:6737390 NA 0.48 6.95 0.53 1.82e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs6598955 0.694 rs6659387 chr1:26634307 G/A cg04990556 chr1:26633338 UBXN11 -0.92 -12.17 -0.74 6.52e-23 Obesity-related traits; TGCT trans rs6089829 0.589 rs73921629 chr20:61676036 G/C cg23505145 chr19:12996616 KLF1 -0.82 -6.62 -0.51 9.6e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1406084 0.636 rs6434941 chr2:154727431 A/G cg25703346 chr2:154729189 GALNT13 -0.77 -4.6 -0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg10117171 chr1:25599238 RHD -0.35 -5.72 -0.46 7.6e-8 Erythrocyte sedimentation rate; TGCT cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg16680214 chr1:154839983 KCNN3 0.36 7.21 0.54 4.8e-11 Prostate cancer; TGCT cis rs6500602 0.592 rs4785966 chr16:4518754 C/T cg06139259 chr16:4526053 HMOX2;NMRAL1 -0.27 -4.67 -0.39 7.81e-6 Schizophrenia; TGCT cis rs9796 0.870 rs72737704 chr15:41323575 C/G cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.41 -0.44 3.06e-7 Menopause (age at onset); TGCT cis rs10191773 0.535 rs56187472 chr2:113111668 G/A cg07905836 chr2:113190072 RGPD8;RGPD5 0.47 4.91 0.4 2.81e-6 Yeast infection; TGCT cis rs2115630 1.000 rs11854313 chr15:85304048 G/C cg12501888 chr15:85177176 SCAND2 -0.48 -4.49 -0.37 1.6e-5 P wave terminal force; TGCT cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg06028808 chr11:68637592 NA 0.55 7.21 0.54 4.8e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13064411 0.696 rs6769516 chr3:113219905 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2486288 0.656 rs11632724 chr15:45550791 G/A cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs986417 1.000 rs10151958 chr14:60977275 T/C cg27398547 chr14:60952738 C14orf39 1.4 10.8 0.7 1.43e-19 Gut microbiota (bacterial taxa); TGCT cis rs8180040 0.553 rs7620997 chr3:47214122 C/T cg27129171 chr3:47204927 SETD2 -0.67 -7.75 -0.57 2.89e-12 Colorectal cancer; TGCT cis rs7824557 0.614 rs4394351 chr8:11212875 G/C cg21775007 chr8:11205619 TDH 0.71 6.81 0.52 3.8e-10 Retinal vascular caliber; TGCT cis rs931127 0.658 rs4930305 chr11:65464000 A/G cg17480646 chr11:65405466 SIPA1 0.42 5.31 0.43 4.97e-7 Systemic lupus erythematosus; TGCT trans rs8073060 0.544 rs225268 chr17:33966224 A/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs12142240 0.660 rs72886903 chr1:46813860 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs4843747 0.605 rs28399183 chr16:88107277 G/A cg06915872 chr16:87998081 BANP -0.29 -4.46 -0.37 1.8e-5 Menopause (age at onset); TGCT cis rs9840812 0.577 rs503973 chr3:136059537 C/G cg15507776 chr3:136538369 TMEM22 -0.59 -5.0 -0.41 1.91e-6 Fibrinogen levels; TGCT cis rs17331151 0.541 rs1139106 chr3:52871101 G/A cg27565382 chr3:53032988 SFMBT1 0.47 5.98 0.47 2.26e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7904368 0.754 rs17139234 chr10:16849732 G/T cg14835575 chr10:16859367 RSU1 0.68 7.5 0.56 1.05e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs4886920 0.694 rs62007851 chr15:78086424 G/A cg25212270 chr15:78015279 NA -0.23 -4.75 -0.39 5.57e-6 Neuroticism; TGCT cis rs9916302 0.904 rs602688 chr17:37439496 C/T cg07936489 chr17:37558343 FBXL20 -0.58 -4.63 -0.38 9.07e-6 Glomerular filtration rate (creatinine); TGCT cis rs7267979 1.000 rs2258563 chr20:25273435 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.29 -0.43 5.34e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.906 rs113857287 chr8:58191683 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -5.33 -0.43 4.56e-7 Developmental language disorder (linguistic errors); TGCT cis rs4566357 0.615 rs10177528 chr2:227913706 G/A cg11843606 chr2:227700838 RHBDD1 -0.53 -5.0 -0.41 1.93e-6 Coronary artery disease; TGCT cis rs11673344 0.504 rs10403728 chr19:37582471 G/C cg08039142 chr19:36980659 ZNF566 0.5 4.6 0.38 1.02e-5 Obesity-related traits; TGCT cis rs11105298 0.891 rs10858881 chr12:89891474 T/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs548987 0.529 rs1165164 chr6:25863481 G/A cg03517284 chr6:25882590 NA -0.62 -5.18 -0.42 8.78e-7 Homocysteine levels; TGCT cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg27286337 chr10:134555280 INPP5A 0.39 4.73 0.39 6.02e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9911578 0.933 rs2632508 chr17:56533235 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.28 0.64 7.12e-16 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.724 rs1304487 chr21:46657283 C/G cg06618935 chr21:46677482 NA 0.35 5.41 0.44 3.12e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9929218 0.953 rs9927329 chr16:68750331 C/T cg01251360 chr16:68772225 CDH1 0.3 5.0 0.41 1.88e-6 Colorectal cancer; TGCT cis rs6089584 0.821 rs2273990 chr20:60579149 G/T cg16423285 chr20:60520624 NA -0.62 -6.99 -0.53 1.46e-10 Body mass index; TGCT cis rs9393777 0.513 rs9393741 chr6:26654189 A/G cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs2486288 0.656 rs2461705 chr15:45570241 A/G cg26924012 chr15:45694286 SPATA5L1 -0.78 -7.59 -0.56 6.49e-12 Glomerular filtration rate; TGCT cis rs7246657 0.722 rs2291002 chr19:38033926 G/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs796364 1.000 rs4263095 chr2:200830137 A/C cg17644776 chr2:200775616 C2orf69 -0.31 -4.85 -0.4 3.58e-6 Schizophrenia; TGCT cis rs28595532 0.920 rs115372254 chr4:119771735 T/C cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs1348850 0.747 rs1047884 chr2:178488281 C/G cg22681709 chr2:178499509 PDE11A -0.44 -5.46 -0.44 2.44e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg00080972 chr5:178986291 RUFY1 0.51 6.02 0.48 1.85e-8 Lung cancer; TGCT cis rs6089584 0.586 rs2296087 chr20:60584328 T/A cg13770153 chr20:60521292 NA -0.45 -5.58 -0.45 1.44e-7 Body mass index; TGCT cis rs4372836 0.541 rs6710080 chr2:28989975 A/G cg09522027 chr2:28974177 PPP1CB -0.73 -7.07 -0.54 9.78e-11 Body mass index; TGCT cis rs2836974 0.897 rs2836973 chr21:40654928 A/G cg11890956 chr21:40555474 PSMG1 1.11 12.43 0.74 1.56e-23 Cognitive function; TGCT trans rs7613875 0.600 rs2624848 chr3:50165101 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.32 -0.64 5.67e-16 Body mass index; TGCT trans rs208520 0.690 rs864314 chr6:66814830 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.08 -16.44 -0.83 5.98e-33 Exhaled nitric oxide output; TGCT cis rs2980439 0.525 rs2945238 chr8:8170136 A/C cg08975724 chr8:8085496 FLJ10661 0.53 4.6 0.38 1.01e-5 Neuroticism; TGCT cis rs67311347 0.577 rs2371129 chr3:40248393 C/T cg13683864 chr3:40499215 RPL14 0.79 7.06 0.54 1.03e-10 Renal cell carcinoma; TGCT cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg12386194 chr3:101231763 SENP7 0.51 5.0 0.41 1.9e-6 Colorectal cancer; TGCT cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs1008375 0.900 rs6812675 chr4:17597549 A/G cg10189774 chr4:17578691 LAP3 0.65 5.28 0.43 5.54e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs769267 0.899 rs3934667 chr19:19431423 T/G cg03709012 chr19:19516395 GATAD2A -0.67 -5.74 -0.46 6.77e-8 Tonsillectomy; TGCT cis rs28785552 0.966 rs7247272 chr19:53236331 C/T cg22067481 chr19:53234126 ZNF611 0.47 6.97 0.53 1.63e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs2535633 0.631 rs2710326 chr3:52995444 T/C cg11645453 chr3:52864694 ITIH4 -0.28 -5.13 -0.42 1.1e-6 Body mass index; TGCT trans rs9329221 0.741 rs58689676 chr8:9806492 T/C cg06636001 chr8:8085503 FLJ10661 -0.77 -6.92 -0.53 2.17e-10 Neuroticism; TGCT cis rs36051895 0.659 rs3780365 chr9:5068520 T/C cg02405213 chr9:5042618 JAK2 -0.86 -12.62 -0.75 5.44e-24 Pediatric autoimmune diseases; TGCT cis rs7429990 0.901 rs7374482 chr3:48168390 A/G cg11946769 chr3:48343235 NME6 -0.54 -4.44 -0.37 1.98e-5 Educational attainment (years of education); TGCT cis rs6088590 1.000 rs6088590 chr20:33313566 T/C cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT trans rs561341 0.941 rs8066558 chr17:30272879 G/T cg20587970 chr11:113659929 NA -1.02 -11.06 -0.7 3.39e-20 Hip circumference adjusted for BMI; TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs826838 0.967 rs7965656 chr12:38807244 G/A cg26384229 chr12:38710491 ALG10B 1.06 10.53 0.69 6.55e-19 Heart rate; TGCT cis rs2197308 0.765 rs12370231 chr12:37917881 T/C cg13010199 chr12:38710504 ALG10B 0.69 5.48 0.44 2.3e-7 Morning vs. evening chronotype; TGCT cis rs17401966 0.931 rs2276100 chr1:10394536 C/G cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs72634258 0.519 rs4908713 chr1:7946831 G/A cg26816564 chr1:7831052 VAMP3 0.64 4.98 0.41 2.05e-6 Inflammatory bowel disease; TGCT trans rs1814175 0.935 rs7950947 chr11:49668369 C/T cg03929089 chr4:120376271 NA -0.63 -7.02 -0.53 1.3e-10 Height; TGCT cis rs2692947 0.526 rs4907225 chr2:96576670 C/T cg13655245 chr2:97463316 CNNM4 0.15 4.51 0.38 1.48e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs533581 0.866 rs4995274 chr16:88970040 T/C cg16701003 chr16:89028210 CBFA2T3 0.35 4.84 0.4 3.77e-6 Social autistic-like traits; TGCT cis rs10479542 0.721 rs6894113 chr5:178974789 G/C cg14820908 chr5:178986412 RUFY1 0.45 4.72 0.39 6.32e-6 Lung cancer; TGCT cis rs4742903 0.967 rs7871759 chr9:106865438 A/G cg21169611 chr9:106856078 SMC2 0.49 4.5 0.37 1.56e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg11644478 chr21:40555479 PSMG1 -0.61 -5.73 -0.46 7.32e-8 Cognitive function; TGCT cis rs1372520 0.577 rs2737028 chr4:90717016 A/G cg20003494 chr4:90757398 SNCA -0.67 -5.24 -0.43 6.74e-7 Neuroticism; TGCT cis rs7267979 1.000 rs6050599 chr20:25400240 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs950776 0.714 rs17408276 chr15:78881618 T/C cg06917634 chr15:78832804 PSMA4 0.66 5.24 0.43 6.65e-7 Sudden cardiac arrest; TGCT cis rs4819052 0.851 rs7276103 chr21:46666078 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.83 0.4 3.87e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7044106 0.762 rs966396 chr9:123453281 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 6.82 0.52 3.48e-10 Hip circumference adjusted for BMI; TGCT cis rs713587 0.875 rs6746013 chr2:25143649 C/G cg15423357 chr2:25149977 NA 0.62 6.34 0.49 3.94e-9 Body mass index in non-asthmatics; TGCT cis rs4788570 0.655 rs2133773 chr16:71812296 A/G cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT trans rs72913475 0.579 rs113848043 chr18:44176945 G/T cg26433034 chr7:128430626 CCDC136 0.61 6.63 0.51 9.33e-10 Midgestational circulating levels of PBDEs (fetal genetic effect); TGCT cis rs6977660 0.714 rs2390157 chr7:19786177 G/A cg07541023 chr7:19748670 TWISTNB 0.81 4.46 0.37 1.81e-5 Thyroid stimulating hormone; TGCT cis rs10791323 0.593 rs2156676 chr11:133715791 G/C cg03690763 chr11:133734501 NA -0.32 -4.92 -0.4 2.67e-6 Childhood ear infection; TGCT cis rs902774 0.585 rs7399070 chr12:53355678 G/C cg19365166 chr12:52695623 KRT86 -0.57 -4.71 -0.39 6.4e-6 Prostate cancer; TGCT cis rs6724607 1.000 rs13410230 chr2:191446252 A/G cg10560079 chr2:191398806 TMEM194B 0.37 5.33 0.43 4.5e-7 Pulse pressure; TGCT cis rs9291683 0.530 rs10939620 chr4:9946132 C/T cg11266682 chr4:10021025 SLC2A9 -0.62 -8.7 -0.62 1.65e-14 Bone mineral density; TGCT cis rs909674 0.818 rs5757678 chr22:39843409 A/G cg01416388 chr22:39784598 NA 0.69 6.49 0.5 1.9e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs17376456 0.877 rs10059630 chr5:93459807 C/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs6570726 0.935 rs432086 chr6:145841593 C/T cg23711669 chr6:146136114 FBXO30 -0.74 -7.05 -0.53 1.1e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.791 rs6853608 chr4:99047916 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4654899 0.897 rs7545133 chr1:21206143 T/G cg01072550 chr1:21505969 NA 0.5 7.91 0.58 1.22e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7523654 0.915 rs10442682 chr1:115864549 C/T cg07790079 chr1:116021925 NA -0.35 -4.44 -0.37 1.96e-5 Schizophrenia; TGCT cis rs734999 0.588 rs2843404 chr1:2530558 T/C cg18854424 chr1:2615690 NA -0.46 -5.36 -0.43 3.84e-7 Ulcerative colitis; TGCT trans rs208520 0.690 rs851465 chr6:66840293 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg10150615 chr22:24372951 LOC391322 -1.01 -13.23 -0.77 1.86e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6964587 1.000 rs11971885 chr7:91674807 T/C cg22709100 chr7:91322751 NA 0.28 4.55 0.38 1.25e-5 Breast cancer; TGCT cis rs377070 0.934 rs309411 chr4:123620150 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.48 5.33 0.43 4.52e-7 Mosquito bite size; TGCT cis rs2692947 0.509 rs4907303 chr2:96217234 C/G cg23100626 chr2:96804247 ASTL 0.41 4.71 0.39 6.59e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2115630 1.000 rs6496452 chr15:85372645 A/T cg12501888 chr15:85177176 SCAND2 -0.53 -5.07 -0.41 1.4e-6 P wave terminal force; TGCT cis rs2067615 0.542 rs4433659 chr12:107082496 G/T cg15890332 chr12:107067104 RFX4 0.29 5.73 0.46 7.31e-8 Heart rate; TGCT cis rs9467711 0.651 rs68194335 chr6:25866243 A/T cg16898833 chr6:26189333 HIST1H4D 1.19 5.48 0.44 2.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs763014 0.898 rs4984897 chr16:632180 G/C cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs892961 0.932 rs7207891 chr17:75413922 G/C cg05865280 chr17:75406074 SEPT9 0.28 6.56 0.51 1.33e-9 Airflow obstruction; TGCT cis rs7959452 0.590 rs11177644 chr12:69785748 A/G cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg22764044 chr5:178986830 RUFY1 0.5 5.57 0.45 1.49e-7 Lung cancer; TGCT cis rs10744422 0.925 rs2292132 chr12:123332834 T/C cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs10833905 0.648 rs2433478 chr11:23034213 T/C cg06387204 chr11:22647648 FANCF 0.56 5.07 0.41 1.41e-6 Sudden cardiac arrest; TGCT cis rs986417 0.818 rs6573319 chr14:61091913 C/G cg27398547 chr14:60952738 C14orf39 1.48 8.31 0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs9467711 0.606 rs2072803 chr6:26392515 G/C cg16898833 chr6:26189333 HIST1H4D 1.14 5.55 0.45 1.65e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7179456 0.545 rs605928 chr15:59046163 C/G cg05156742 chr15:59063176 FAM63B 0.48 4.8 0.4 4.56e-6 Asperger disorder; TGCT cis rs514406 0.505 rs437954 chr1:53173321 C/G cg24675658 chr1:53192096 ZYG11B -0.78 -9.22 -0.64 9.75e-16 Monocyte count; TGCT cis rs6988636 1.000 rs10096350 chr8:124184470 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs5769765 0.954 rs5770707 chr22:50244533 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.08 11.84 0.73 4.29e-22 Schizophrenia; TGCT cis rs17253792 0.822 rs28549152 chr14:56091239 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg16590910 chr6:42928470 GNMT -0.49 -4.57 -0.38 1.16e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1799949 1.000 rs8070085 chr17:41341984 C/T cg10047753 chr17:41438598 NA -0.79 -8.0 -0.58 7.37e-13 Menopause (age at onset); TGCT cis rs3020736 0.500 rs9620026 chr22:42498578 C/T cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs28595532 0.841 rs115516095 chr4:119760096 A/C cg21605333 chr4:119757512 SEC24D 1.55 8.04 0.59 6.15e-13 Cannabis dependence symptom count; TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg04025307 chr7:1156635 C7orf50 0.22 4.95 0.41 2.41e-6 Longevity;Endometriosis; TGCT cis rs1218582 0.661 rs4845695 chr1:154911798 A/G cg16680214 chr1:154839983 KCNN3 -0.38 -8.26 -0.6 1.85e-13 Prostate cancer; TGCT cis rs4689388 0.609 rs1046319 chr4:6304286 C/T cg14416269 chr4:6271139 WFS1 0.48 5.76 0.46 6.11e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2439831 1.000 rs690436 chr15:43761205 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs17376456 0.877 rs10064520 chr5:93427358 T/C cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs9653442 0.863 rs10865035 chr2:100835734 A/G cg22139774 chr2:100720529 AFF3 -0.42 -7.5 -0.56 1.04e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2033711 0.870 rs6510152 chr19:58953319 C/T cg13877915 chr19:58951672 ZNF132 0.91 11.22 0.71 1.32e-20 Uric acid clearance; TGCT cis rs858239 0.899 rs10262243 chr7:23290987 G/A cg05602783 chr7:23145260 KLHL7 -0.63 -4.96 -0.41 2.31e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7959452 0.535 rs7135092 chr12:69658330 T/C cg14784868 chr12:69753453 YEATS4 0.69 7.03 0.53 1.23e-10 Blood protein levels; TGCT cis rs9311474 0.629 rs9853056 chr3:52555957 T/C cg10802521 chr3:52805072 NEK4 -0.64 -7.48 -0.56 1.16e-11 Electroencephalogram traits; TGCT cis rs17221829 0.525 rs9804670 chr11:89375801 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs16867321 1.000 rs10185265 chr2:181438860 G/C cg23363182 chr2:181467187 NA -0.39 -5.47 -0.44 2.42e-7 Obesity; TGCT cis rs651907 0.535 rs58658478 chr3:101511667 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.15 0.67 5.47e-18 Colorectal cancer; TGCT cis rs7428 0.520 rs7605890 chr2:85559525 A/C cg03728395 chr2:85555865 TGOLN2 -0.29 -5.03 -0.41 1.7e-6 Ear protrusion; TGCT cis rs478304 0.654 rs1074155 chr11:65458197 C/T cg17480646 chr11:65405466 SIPA1 0.61 8.23 0.59 2.15e-13 Acne (severe); TGCT cis rs798554 0.679 rs1639066 chr7:2892972 A/G cg13628971 chr7:2884303 GNA12 0.55 4.6 0.38 1.04e-5 Height; TGCT cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.69 4.6 0.38 1.02e-5 Platelet count; TGCT trans rs4650994 1.000 rs10798619 chr1:178532517 A/G cg05059571 chr16:84539110 KIAA1609 -0.4 -7.39 -0.55 1.94e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs35306767 0.903 rs4522091 chr10:874116 G/T cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg12419862 chr22:24373484 LOC391322 0.87 7.68 0.57 4.09e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg05738196 chr6:26577821 NA 0.88 11.01 0.7 4.39e-20 Intelligence (multi-trait analysis); TGCT cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg16325326 chr1:53192061 ZYG11B -0.7 -8.6 -0.61 2.87e-14 Monocyte count; TGCT cis rs2204008 0.837 rs11168341 chr12:37961951 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs9549260 0.739 rs7330614 chr13:41199421 G/A cg21288729 chr13:41239152 FOXO1 0.99 10.47 0.69 8.86e-19 Red blood cell count; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.94 0.41 2.5e-6 Prudent dietary pattern; TGCT cis rs6540559 0.546 rs7551944 chr1:210029430 G/C cg22029157 chr1:209979665 IRF6 0.79 5.77 0.46 5.96e-8 Cleft lip with or without cleft palate; TGCT trans rs4650994 1.000 rs6660445 chr1:178528871 C/T cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.54e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg02458000 chr6:26745757 NA 0.55 5.25 0.43 6.28e-7 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.563 rs1796687 chr6:8536118 C/G cg23788917 chr6:8435910 SLC35B3 0.61 5.5 0.44 2.09e-7 Motion sickness; TGCT cis rs10791097 0.547 rs1050078 chr11:130746146 T/C cg12179176 chr11:130786555 SNX19 0.85 10.17 0.67 4.79e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3796352 1.000 rs71299622 chr3:52917038 G/A cg07884673 chr3:53033167 SFMBT1 0.6 4.88 0.4 3.16e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs4730250 0.640 rs7783562 chr7:106917438 G/T cg02696742 chr7:106810147 HBP1 -0.68 -5.27 -0.43 5.73e-7 Osteoarthritis; TGCT cis rs7953508 0.659 rs1316739 chr12:93968256 G/A cg18151635 chr12:93972918 NA -0.19 -4.47 -0.37 1.71e-5 Pubertal anthropometrics; TGCT cis rs709400 0.663 rs1022736 chr14:103998423 G/C cg26031613 chr14:104095156 KLC1 0.89 9.8 0.66 3.77e-17 Body mass index; TGCT cis rs7666738 0.830 rs4699597 chr4:99019031 G/A cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs7726839 0.540 rs4957080 chr5:644552 A/C cg11887960 chr12:57824829 NA -1.12 -9.19 -0.64 1.16e-15 Obesity-related traits; TGCT cis rs4499344 0.730 rs28416849 chr19:33099758 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs11677370 0.603 rs10178523 chr2:3854169 G/A cg17052675 chr2:3827356 NA -0.43 -7.08 -0.54 9.26e-11 Type 2 diabetes; TGCT cis rs9430161 0.564 rs12081176 chr1:11034145 T/C cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg16145915 chr7:1198662 ZFAND2A -0.62 -8.99 -0.63 3.4e-15 Longevity;Endometriosis; TGCT cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.79e-6 Obesity-related traits; TGCT cis rs72781680 0.898 rs2339851 chr2:23938883 G/A cg08917208 chr2:24149416 ATAD2B 0.9 5.58 0.45 1.46e-7 Lymphocyte counts; TGCT cis rs7772486 0.875 rs9373483 chr6:146364194 A/G cg23711669 chr6:146136114 FBXO30 0.87 9.53 0.65 1.75e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs709400 0.567 rs1961600 chr14:103862144 G/A cg26031613 chr14:104095156 KLC1 0.85 9.32 0.64 5.53e-16 Body mass index; TGCT cis rs9970334 0.596 rs709209 chr1:6278414 A/G cg15892785 chr1:6309343 GPR153 -0.39 -4.56 -0.38 1.23e-5 Resting heart rate; TGCT cis rs1461503 0.966 rs10892938 chr11:122841921 A/C cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs2735413 0.564 rs11859770 chr16:78126734 A/G cg09132178 chr16:78079569 NA 0.35 4.51 0.38 1.47e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs4862750 0.914 rs1991255 chr4:187875340 G/A cg03452623 chr4:187889614 NA -0.38 -5.86 -0.47 3.82e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6840360 1.000 rs6846114 chr4:152604558 A/G cg17479576 chr4:152424074 FAM160A1 0.52 5.31 0.43 4.96e-7 Intelligence (multi-trait analysis); TGCT cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg21644426 chr2:191273491 MFSD6 0.6 6.01 0.47 1.92e-8 Pulse pressure; TGCT cis rs11252926 0.528 rs11252090 chr10:436547 C/T cg18196295 chr10:418757 DIP2C -0.29 -4.86 -0.4 3.46e-6 Psychosis in Alzheimer's disease; TGCT trans rs7819412 0.654 rs4840550 chr8:11029029 T/G cg15556689 chr8:8085844 FLJ10661 -0.84 -7.91 -0.58 1.19e-12 Triglycerides; TGCT cis rs3782455 1.000 rs75409372 chr12:114405283 C/T cg10631684 chr12:113795897 PLBD2 -0.8 -5.2 -0.42 7.83e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9549260 0.592 rs9532588 chr13:41302913 G/A cg21288729 chr13:41239152 FOXO1 0.92 8.87 0.62 6.71e-15 Red blood cell count; TGCT cis rs7208859 0.623 rs57486336 chr17:29085731 G/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10504229 1.000 rs68114352 chr8:58196081 C/T cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.846 rs372904 chr6:145887425 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9372498 0.505 rs9489493 chr6:118992323 T/C cg07617317 chr6:118971624 C6orf204 0.45 4.83 0.4 3.93e-6 Diastolic blood pressure; TGCT cis rs2050392 0.762 rs306587 chr10:30722908 G/C cg18806716 chr10:30721971 MAP3K8 -0.49 -5.65 -0.45 1.04e-7 Inflammatory bowel disease; TGCT cis rs16866061 0.962 rs16825685 chr2:225434256 C/G cg12698349 chr2:225449008 CUL3 1.01 9.99 0.67 1.35e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs907683 0.584 rs2854903 chr2:220288979 C/T cg15015639 chr2:220282977 DES -0.4 -4.98 -0.41 2.09e-6 Resting heart rate; TGCT cis rs28595532 0.920 rs56124677 chr4:119772213 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs9291683 0.692 rs1558489 chr4:10325489 T/A cg11266682 chr4:10021025 SLC2A9 -0.47 -5.46 -0.44 2.45e-7 Bone mineral density; TGCT cis rs1008375 0.932 rs6845288 chr4:17665498 A/T cg16339924 chr4:17578868 LAP3 -0.62 -5.0 -0.41 1.91e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg03517284 chr6:25882590 NA -0.59 -5.24 -0.43 6.78e-7 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.92 7.56 0.56 7.89e-12 Platelet count; TGCT cis rs7772486 0.875 rs2777484 chr6:146334162 A/G cg23711669 chr6:146136114 FBXO30 0.84 9.04 0.63 2.6e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs6901250 1.000 rs615199 chr6:117113653 T/C cg12892004 chr6:117198278 RFX6 0.45 4.98 0.41 2.08e-6 C-reactive protein levels; TGCT cis rs7666738 0.830 rs17548431 chr4:98923768 C/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9650657 0.803 rs13276026 chr8:10609955 G/A cg27411982 chr8:10470053 RP1L1 -0.22 -4.61 -0.38 9.97e-6 Neuroticism; TGCT cis rs57221529 0.713 rs56328416 chr5:591138 G/A cg16624210 chr5:671434 TPPP 0.41 4.56 0.38 1.19e-5 Lung disease severity in cystic fibrosis; TGCT cis rs4919694 1.000 rs17881215 chr10:104629236 G/C cg04362960 chr10:104952993 NT5C2 1.05 7.22 0.54 4.57e-11 Arsenic metabolism; TGCT cis rs877282 0.945 rs71489301 chr10:770191 A/G cg17470449 chr10:769945 NA 0.35 5.19 0.42 8.21e-7 Uric acid levels; TGCT cis rs2456568 0.802 rs11020586 chr11:93638547 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.09e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6582630 0.555 rs34730221 chr12:38405140 C/T cg26384229 chr12:38710491 ALG10B -0.79 -7.16 -0.54 6.29e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg18538332 chr22:24372958 LOC391322 0.88 7.7 0.57 3.69e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7568458 0.875 rs2044474 chr2:85758790 G/A cg17127132 chr2:85788382 GGCX 0.72 6.68 0.51 7.16e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs11190604 1.000 rs10883509 chr10:102296461 C/T cg16342193 chr10:102329863 NA -0.42 -5.32 -0.43 4.58e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4631830 0.869 rs11006207 chr10:51538176 T/C cg10326726 chr10:51549505 MSMB -0.26 -5.3 -0.43 5.07e-7 Prostate-specific antigen levels; TGCT cis rs116095464 0.558 rs10075018 chr5:239175 G/A cg22857025 chr5:266934 NA -0.34 -6.3 -0.49 4.7e-9 Breast cancer; TGCT cis rs6912958 0.781 rs3934838 chr6:88284699 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs7103648 0.603 rs3740688 chr11:47380340 G/T cg20307385 chr11:47447363 PSMC3 0.74 7.1 0.54 8.35e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs11098499 0.954 rs28685688 chr4:120420334 T/C cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs72843506 0.722 rs16942325 chr17:20027063 A/G cg18979559 chr17:20280153 CCDC144C -0.64 -4.78 -0.39 4.97e-6 Schizophrenia; TGCT cis rs7917772 0.636 rs7069489 chr10:104525371 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.57 4.78 0.39 4.78e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7178572 0.568 rs1389436 chr15:77665848 G/T cg22256960 chr15:77711686 NA -0.87 -9.0 -0.63 3.34e-15 Type 2 diabetes; TGCT cis rs2204008 0.687 rs1733404 chr12:38123395 G/T cg13010199 chr12:38710504 ALG10B -0.6 -4.8 -0.4 4.57e-6 Bladder cancer; TGCT cis rs1005277 0.579 rs2505196 chr10:38393563 G/A cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs12477438 0.520 rs1453563 chr2:99720267 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs7772486 0.875 rs2224120 chr6:146343280 A/C cg05347473 chr6:146136440 FBXO30 0.56 5.29 0.43 5.34e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9913156 0.517 rs11868227 chr17:4614539 G/A cg00122941 chr17:4613640 ARRB2 0.78 7.08 0.54 9.62e-11 Lymphocyte counts; TGCT cis rs514406 0.505 rs431427 chr1:53179094 C/A cg25767906 chr1:53392781 SCP2 -0.47 -5.35 -0.43 4.15e-7 Monocyte count; TGCT cis rs9581857 0.615 rs9581848 chr13:28003997 C/T cg22138327 chr13:27999177 GTF3A 0.8 5.52 0.44 1.9e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6918586 0.658 rs198813 chr6:26128226 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.66 -6.21 -0.49 7.2e-9 Schizophrenia; TGCT cis rs2549003 0.811 rs10072700 chr5:131816903 A/C cg21138405 chr5:131827807 IRF1 0.23 5.55 0.45 1.68e-7 Asthma (sex interaction); TGCT cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs6089829 1.000 rs6089829 chr20:61669036 C/T cg18188782 chr20:61659543 NA -0.44 -5.19 -0.42 8.41e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7714584 1.000 rs10463240 chr5:150256853 A/C cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs4820539 1.000 rs13054985 chr22:23458577 G/A cg14186256 chr22:23484241 RTDR1 0.94 11.29 0.71 8.9e-21 Bone mineral density; TGCT cis rs35883536 0.626 rs34752753 chr1:101045193 T/G cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs2046867 0.908 rs4677206 chr3:72780052 A/T cg25664220 chr3:72788482 NA 0.53 6.81 0.52 3.8e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs12681288 0.523 rs11137122 chr8:954702 A/G cg04851639 chr8:1020857 NA -0.27 -4.47 -0.37 1.75e-5 Schizophrenia; TGCT cis rs10504229 0.954 rs903717 chr8:58167856 A/G cg24829409 chr8:58192753 C8orf71 -0.48 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs2046867 0.818 rs17010188 chr3:72870351 T/C cg25664220 chr3:72788482 NA -0.56 -7.04 -0.53 1.16e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2274471 0.645 rs10974955 chr9:5090641 G/A cg03390472 chr9:5043263 JAK2 -0.29 -4.63 -0.38 8.95e-6 Crohn's disease; TGCT cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs6089829 0.962 rs4809455 chr20:61660781 G/C cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs2688608 0.592 rs11000759 chr10:75493726 G/A cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs7666738 0.791 rs2903142 chr4:99040071 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs4650994 0.505 rs2811291 chr1:178574217 C/T cg05059571 chr16:84539110 KIAA1609 0.51 10.23 0.68 3.51e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg12667521 chr19:29218732 NA 0.53 5.63 0.45 1.16e-7 Methadone dose in opioid dependence; TGCT cis rs12776158 0.901 rs57677741 chr10:71217131 G/A cg12610070 chr10:71211762 TSPAN15 -0.59 -5.17 -0.42 9.16e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg23205692 chr1:25664452 TMEM50A 0.52 5.36 0.43 3.88e-7 Erythrocyte sedimentation rate; TGCT cis rs10501293 0.956 rs12361827 chr11:43137261 T/C cg03447554 chr11:43094025 NA -0.44 -5.66 -0.45 9.93e-8 Cognitive performance; TGCT cis rs1371867 0.817 rs1788179 chr8:101333345 A/G cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs7020830 0.867 rs1472169 chr9:37209396 C/T cg14294708 chr9:37120828 ZCCHC7 1.21 16.19 0.82 2.22e-32 Schizophrenia; TGCT cis rs9660180 0.836 rs72634845 chr1:1704899 G/A cg23982607 chr1:1823379 GNB1 -0.55 -8.57 -0.61 3.52e-14 Body mass index; TGCT cis rs116095464 0.558 rs10067021 chr5:221490 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs6951245 0.872 rs11768486 chr7:1101290 C/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9436747 0.641 rs11208679 chr1:66049738 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.57 5.16 0.42 9.52e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg11211951 chr8:145729740 GPT -0.24 -5.66 -0.45 1.01e-7 Age at first birth; TGCT cis rs4253772 0.786 rs4253765 chr22:46622888 C/T cg09491104 chr22:46646882 C22orf40 -0.46 -4.56 -0.38 1.23e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs9393777 0.513 rs13215020 chr6:26656073 G/A cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs1801251 1.000 rs1446311 chr2:233705071 G/A cg25237894 chr2:233734115 C2orf82 -0.33 -5.94 -0.47 2.71e-8 Coronary artery disease; TGCT cis rs3849570 0.673 rs9877408 chr3:81974558 A/G cg07356753 chr3:81810745 GBE1 -0.64 -5.63 -0.45 1.16e-7 Waist circumference;Body mass index; TGCT cis rs79349575 0.783 rs62075820 chr17:46983171 G/C cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg17179660 chr6:151773299 C6orf211;RMND1 -0.57 -5.42 -0.44 2.99e-7 Menarche (age at onset); TGCT cis rs4478037 0.822 rs4320035 chr3:33113697 C/G cg19404215 chr3:33155277 CRTAP -1.24 -5.97 -0.47 2.36e-8 Major depressive disorder; TGCT cis rs7666738 0.830 rs34628820 chr4:99004764 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12579753 0.917 rs76240969 chr12:82195236 C/A cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs9814567 0.752 rs4955542 chr3:134328740 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9972944 0.729 rs1541609 chr17:63773564 G/A cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs1799949 1.000 rs8176242 chr17:41217874 C/T cg10047753 chr17:41438598 NA 0.96 9.65 0.65 9.13e-17 Menopause (age at onset); TGCT cis rs5769707 0.967 rs5769698 chr22:49997706 A/G cg20744362 chr22:50050164 C22orf34 0.28 4.58 0.38 1.11e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg00684032 chr4:1343700 KIAA1530 0.22 4.9 0.4 2.93e-6 Obesity-related traits; TGCT cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg09222892 chr1:25734099 RHCE -0.44 -7.16 -0.54 6.35e-11 Erythrocyte sedimentation rate; TGCT cis rs6598955 0.671 rs12145403 chr1:26597189 C/T cg04990556 chr1:26633338 UBXN11 0.7 5.64 0.45 1.09e-7 Obesity-related traits; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.52 5.76 0.46 6.2e-8 Lymphocyte counts; TGCT cis rs2230307 0.505 rs571579 chr1:100617372 G/A cg24955406 chr1:100503596 HIAT1 -0.72 -4.83 -0.4 3.92e-6 Carotid intima media thickness; TGCT cis rs13323323 0.691 rs9815769 chr3:44663014 A/T cg04389838 chr3:44770851 ZNF501 -0.43 -4.62 -0.38 9.46e-6 IgG glycosylation; TGCT cis rs3617 0.625 rs11715347 chr3:52883070 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2075371 0.829 rs1993058 chr7:133930361 G/A cg11752832 chr7:134001865 SLC35B4 0.67 5.54 0.45 1.76e-7 Mean platelet volume; TGCT cis rs7681440 0.904 rs10004413 chr4:90769479 T/C cg26578617 chr4:90757533 SNCA -0.46 -4.83 -0.4 3.96e-6 Dementia with Lewy bodies; TGCT trans rs1005277 0.557 rs2983338 chr10:38550734 C/T cg27523141 chr10:43048294 ZNF37B 0.71 8.11 0.59 4.13e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6988636 1.000 rs60827294 chr8:124187842 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs7568458 0.684 rs7593969 chr2:85809670 A/G cg17127132 chr2:85788382 GGCX -0.51 -4.49 -0.37 1.61e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9425326 0.508 rs2491432 chr1:183813558 C/G cg15569801 chr1:184197096 NA -0.14 -5.03 -0.41 1.7e-6 Antipsychotic drug-induced QTc interval change in schizophrenia; TGCT cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs9527 0.615 rs7096452 chr10:104736563 G/A cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs6496667 0.609 rs7183707 chr15:90883733 G/T cg22089800 chr15:90895588 ZNF774 0.64 5.43 0.44 2.83e-7 Rheumatoid arthritis; TGCT cis rs9300255 0.602 rs1716167 chr12:123651162 C/T cg00376283 chr12:123451042 ABCB9 -0.72 -5.55 -0.45 1.65e-7 Neutrophil percentage of white cells; TGCT cis rs72781680 1.000 rs7594510 chr2:24173377 A/G cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs7666738 0.830 rs11947027 chr4:99005941 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6840360 0.593 rs10033405 chr4:152474489 A/G cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs8141529 0.702 rs469991 chr22:29307859 G/C cg02153584 chr22:29168773 CCDC117 -0.6 -4.74 -0.39 5.81e-6 Lymphocyte counts; TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs2204008 0.627 rs1851117 chr12:38398987 G/T cg26384229 chr12:38710491 ALG10B 0.83 7.39 0.55 1.92e-11 Bladder cancer; TGCT trans rs17685 0.884 rs6978677 chr7:75636240 C/T cg19862616 chr7:65841803 NCRNA00174 0.48 7.14 0.54 6.84e-11 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs9291683 0.530 rs17246501 chr4:9985710 A/C cg11266682 chr4:10021025 SLC2A9 0.62 8.49 0.61 5.31e-14 Bone mineral density; TGCT cis rs11190604 1.000 rs3793771 chr10:102222957 C/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs5769765 0.955 rs8135816 chr22:50291976 G/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.86 -0.73 3.71e-22 Schizophrenia; TGCT cis rs854765 0.663 rs2236513 chr17:17747366 A/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.55 -0.51 1.39e-9 Total body bone mineral density; TGCT cis rs7119 0.689 rs11630557 chr15:77820712 A/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.61 -0.38 9.7e-6 Type 2 diabetes; TGCT cis rs11190604 1.000 rs7084810 chr10:102297546 A/G cg16342193 chr10:102329863 NA -0.41 -5.11 -0.42 1.18e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10197940 0.624 rs6731486 chr2:152410732 C/T cg06191203 chr2:152266755 RIF1 0.74 6.95 0.53 1.81e-10 Lung cancer; TGCT cis rs6967414 0.681 rs11979878 chr7:6753803 A/G cg09896999 chr7:6746977 ZNF12 -0.57 -6.43 -0.5 2.5e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs13191362 1.000 rs13202339 chr6:163081812 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.36 0.6 1.07e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6964587 1.000 rs6465343 chr7:91618208 T/C cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs36051895 0.559 rs72701680 chr9:5207294 A/T cg02405213 chr9:5042618 JAK2 -0.7 -8.74 -0.62 1.37e-14 Pediatric autoimmune diseases; TGCT cis rs6952808 0.626 rs57633152 chr7:2042547 C/G cg04267008 chr7:1944627 MAD1L1 -0.41 -5.31 -0.43 4.95e-7 Bipolar disorder and schizophrenia; TGCT cis rs2243480 1.000 rs316327 chr7:65609201 G/T cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs13256369 1.000 rs12550762 chr8:8576535 T/A cg18904891 chr8:8559673 CLDN23 0.64 5.87 0.47 3.71e-8 Obesity-related traits; TGCT cis rs9303401 0.659 rs17741087 chr17:56550300 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.17 0.48 8.95e-9 Cognitive test performance; TGCT trans rs7819412 0.537 rs2127127 chr8:11434792 C/G cg06636001 chr8:8085503 FLJ10661 -0.73 -6.79 -0.52 4.12e-10 Triglycerides; TGCT cis rs3806843 0.735 rs2563335 chr5:140044292 A/C cg19875535 chr5:140030758 IK 0.36 6.15 0.48 9.57e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs10791323 0.536 rs1944731 chr11:133726067 G/A cg03690763 chr11:133734501 NA -0.3 -4.53 -0.38 1.38e-5 Childhood ear infection; TGCT cis rs9611565 0.649 rs5758442 chr22:42133060 T/C cg13695892 chr22:41940480 POLR3H 0.84 7.96 0.58 9.2e-13 Vitiligo; TGCT trans rs7618501 1.000 rs6785549 chr3:49736565 G/A cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs886126 1.000 rs886126 chr12:111679214 C/T cg10833066 chr12:111807467 FAM109A 0.32 5.34 0.43 4.35e-7 Coronary heart disease; TGCT cis rs1018836 0.608 rs2142146 chr8:91464808 T/C cg16814680 chr8:91681699 NA -0.77 -7.8 -0.57 2.21e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs873917 0.577 rs784611 chr1:40125988 T/A cg06209491 chr1:40138402 NT5C1A -0.35 -5.84 -0.46 4.21e-8 Amyotrophic lateral sclerosis; TGCT cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.58e-9 Gut microbiome composition (summer); TGCT cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.87 -10.4 -0.68 1.33e-18 Prudent dietary pattern; TGCT cis rs34638686 1 rs34638686 chr3:48682658 C/T cg00383909 chr3:49044727 WDR6 0.9 4.71 0.39 6.49e-6 Educational attainment (years of education); TGCT cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg15691649 chr6:25882328 NA 0.48 5.55 0.45 1.63e-7 Blood metabolite levels; TGCT cis rs7095607 0.579 rs6480308 chr10:69952953 T/C cg18986048 chr10:69913749 MYPN 0.57 6.15 0.48 9.78e-9 Lung function (FVC); TGCT cis rs1061377 1.000 rs9990742 chr4:39121414 G/A cg24403649 chr4:39172243 NA 0.19 4.47 0.37 1.75e-5 Uric acid levels; TGCT cis rs270601 0.633 rs733300 chr5:131572243 A/G cg12564285 chr5:131593104 PDLIM4 0.37 4.44 0.37 1.98e-5 Acylcarnitine levels; TGCT cis rs3947 0.789 rs1293322 chr8:11692638 C/T cg02840367 chr8:11660030 FDFT1 0.87 6.32 0.49 4.21e-9 Blood protein levels; TGCT cis rs114540395 0.920 rs115066444 chr10:103461443 G/C cg03300883 chr10:102748874 C10orf2 0.43 4.51 0.38 1.48e-5 Schizophrenia; TGCT cis rs1153858 1.000 rs72623915 chr15:45647433 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs6089829 0.851 rs4809460 chr20:61661355 T/C cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs9486719 1.000 rs11153067 chr6:97039421 A/T cg06623918 chr6:96969491 KIAA0776 0.97 7.71 0.57 3.47e-12 Migraine;Coronary artery disease; TGCT cis rs9527 0.590 rs10883836 chr10:104891198 T/C cg04362960 chr10:104952993 NT5C2 0.69 5.82 0.46 4.78e-8 Arsenic metabolism; TGCT cis rs6089829 0.925 rs4809270 chr20:61676709 C/A cg18188782 chr20:61659543 NA 0.45 4.94 0.41 2.51e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs77216612 0.835 rs10845621 chr12:12887977 C/T cg04607235 chr12:12878440 APOLD1 -0.97 -8.51 -0.61 4.81e-14 Lymphocyte counts; TGCT cis rs7666738 0.830 rs10001702 chr4:99065160 T/G cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg26818010 chr10:134567672 INPP5A 0.33 4.92 0.4 2.64e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2404602 0.669 rs12438540 chr15:76943213 C/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs9297145 0.761 rs62473015 chr7:98763301 G/A cg05967295 chr7:98741636 SMURF1 0.99 12.81 0.75 1.84e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs8070740 1.000 rs4790772 chr17:5330959 C/G cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.44 0.37 1.96e-5 Menopause (age at onset); TGCT cis rs10504229 0.683 rs2318144 chr8:58114743 G/A cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.71e-7 Developmental language disorder (linguistic errors); TGCT cis rs1008375 1.000 rs3815413 chr4:17654648 T/C cg18681998 chr4:17616180 MED28 1.06 12.43 0.74 1.57e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10875595 0.509 rs115819920 chr5:140663745 A/C cg24830062 chr5:140700576 TAF7 -0.6 -5.08 -0.42 1.34e-6 Pulmonary function decline; TGCT cis rs9787249 0.957 rs56064244 chr1:40213890 C/T cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs72781680 0.898 rs17462433 chr2:24012758 T/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs9611565 0.592 rs12484467 chr22:41957610 T/C cg06634786 chr22:41940651 POLR3H -0.82 -7.52 -0.56 9.36e-12 Vitiligo; TGCT cis rs2180341 1.000 rs7756336 chr6:127650299 T/C cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs10029849 chr4:99059362 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs73058052 0.597 rs2288921 chr19:50092002 G/T cg09250473 chr19:50168907 IRF3;BCL2L12 -0.68 -5.61 -0.45 1.23e-7 Fibrinogen levels; TGCT cis rs7666738 0.830 rs35685312 chr4:98858521 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1372520 0.808 rs1372518 chr4:90757294 A/C cg20003494 chr4:90757398 SNCA -0.65 -5.17 -0.42 9.26e-7 Neuroticism; TGCT cis rs4720575 1.000 rs7791050 chr7:47086452 T/C cg00036614 chr7:47093842 NA -0.2 -5.08 -0.42 1.35e-6 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs904251 0.861 rs1776456 chr6:37484698 C/G cg25019722 chr6:37503610 NA -0.49 -6.78 -0.52 4.4e-10 Cognitive performance; TGCT cis rs2153535 0.580 rs7341382 chr6:8470549 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs8013055 0.796 rs4075105 chr14:106000231 C/T cg19700328 chr14:106028568 NA -0.46 -5.14 -0.42 1.05e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7829975 0.539 rs940031 chr8:8546848 C/T cg06636001 chr8:8085503 FLJ10661 -0.59 -5.06 -0.41 1.5e-6 Mood instability; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg04234412 chr22:24373322 LOC391322 -0.89 -9.44 -0.65 2.84e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9948 0.655 rs17119591 chr2:97435557 G/A cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT trans rs8073060 0.586 rs7221203 chr17:34015532 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6582630 0.519 rs11514372 chr12:38308613 T/G cg26384229 chr12:38710491 ALG10B 0.82 7.23 0.54 4.32e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs151997 0.538 rs62367392 chr5:50270298 T/C cg06027927 chr5:50259733 NA 0.56 5.72 0.46 7.4e-8 Callous-unemotional behaviour; TGCT trans rs2727020 0.729 rs1917325 chr11:49370004 G/A cg15704280 chr7:45808275 SEPT13 -0.74 -8.45 -0.6 6.53e-14 Coronary artery disease; TGCT cis rs12477438 1.000 rs73963398 chr2:99887025 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.81 -0.62 9.23e-15 Chronic sinus infection; TGCT cis rs9911578 1.000 rs4372750 chr17:57013803 A/C cg05425664 chr17:57184151 TRIM37 0.62 6.18 0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.545 rs2736303 chr8:11236850 C/T cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs8056742 0.730 rs74033925 chr16:85083032 G/T cg00229868 chr16:85520891 NA 0.38 5.13 0.42 1.1e-6 Amyotrophic lateral sclerosis; TGCT cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -6.46 -0.5 2.17e-9 Alzheimer's disease; TGCT cis rs7226408 0.948 rs72885226 chr18:34401806 G/A cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs2816062 0.813 rs2745318 chr1:18895844 C/T cg18795169 chr1:18902165 NA 0.6 14.1 0.78 1.57e-27 Urate levels in lean individuals; TGCT cis rs669446 0.528 rs7538463 chr1:44196416 T/A cg12908607 chr1:44402522 ARTN -0.62 -7.25 -0.55 3.99e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs1577917 1.000 rs12215037 chr6:86727631 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.36 -0.43 3.86e-7 Response to antipsychotic treatment; TGCT cis rs910316 1.000 rs8003506 chr14:75586288 A/C cg11812906 chr14:75593930 NEK9 -0.72 -7.32 -0.55 2.73e-11 Height; TGCT cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs7727544 0.735 rs274558 chr5:131721174 A/G cg24060327 chr5:131705240 SLC22A5 0.58 6.45 0.5 2.23e-9 Blood metabolite levels; TGCT cis rs12500482 0.935 rs12644638 chr4:2413461 C/T cg01601518 chr4:2404284 ZFYVE28 -0.32 -5.4 -0.44 3.31e-7 Cognitive function; TGCT cis rs7547997 0.615 rs716221 chr1:158303872 C/T cg03528325 chr1:158223921 CD1A 0.33 4.58 0.38 1.1e-5 QRS duration; TGCT cis rs4654899 0.680 rs4654881 chr1:21209769 T/C cg01072550 chr1:21505969 NA 0.52 8.4 0.6 8.89e-14 Superior frontal gyrus grey matter volume; TGCT cis rs938554 0.513 rs3775947 chr4:9995240 C/T cg02734326 chr4:10020555 SLC2A9 0.53 4.92 0.4 2.71e-6 Blood metabolite levels; TGCT cis rs4629710 0.545 rs11755717 chr6:131547028 A/T cg12606694 chr6:131520996 AKAP7 -0.39 -4.79 -0.39 4.76e-6 Multiple myeloma (IgH translocation); TGCT cis rs10504229 0.683 rs7460059 chr8:58111561 C/T cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs1670533 1.000 rs7685541 chr4:1058501 G/A cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs13191362 1.000 rs36007635 chr6:163009335 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg08736216 chr1:53307985 ZYG11A -0.25 -4.96 -0.41 2.22e-6 Monocyte count; TGCT cis rs3820068 0.581 rs16851851 chr1:15929628 C/G cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs231513 0.906 rs11657450 chr17:42002464 C/T cg26893861 chr17:41843967 DUSP3 0.74 5.18 0.42 8.54e-7 Cognitive function; TGCT cis rs447735 0.537 rs7190341 chr16:89917537 T/C cg08627397 chr16:89984028 MC1R -0.35 -5.21 -0.42 7.79e-7 Hemoglobin concentration; TGCT cis rs682748 0.791 rs1875538 chr5:17145198 C/A cg23987134 chr5:17158319 LOC285696 -0.23 -5.55 -0.45 1.67e-7 Hippocampal atrophy; TGCT cis rs797680 0.856 rs11164876 chr1:93630510 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.0 -0.41 1.88e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7267979 1.000 rs6083805 chr20:25317356 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17767294 0.708 rs77450054 chr6:28083949 G/A cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs1372520 0.684 rs2619347 chr4:90745770 G/A cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs2836950 0.545 rs2836922 chr21:40516308 C/T cg11644478 chr21:40555479 PSMG1 -0.59 -5.73 -0.46 7.13e-8 Menarche (age at onset); TGCT cis rs1799949 1.000 rs4340367 chr17:41307772 G/A cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg17178900 chr1:205818956 PM20D1 0.58 7.19 0.54 5.32e-11 Menarche (age at onset); TGCT cis rs34754277 0.636 rs1966228 chr1:118144332 C/T cg03653317 chr1:118165598 FAM46C 0.19 4.65 0.39 8.35e-6 Immature fraction of reticulocytes; TGCT cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg23649088 chr2:200775458 C2orf69 0.47 9.78 0.66 4.27e-17 Osteoporosis; TGCT cis rs13256369 0.950 rs12548792 chr8:8568031 T/C cg18904891 chr8:8559673 CLDN23 0.59 5.54 0.45 1.73e-7 Obesity-related traits; TGCT trans rs77457752 0.690 rs10113975 chr9:13912482 A/C cg12973904 chr7:149457885 NA 0.42 6.88 0.53 2.59e-10 Breast cancer; TGCT trans rs629535 0.814 rs78813708 chr8:70073977 A/G cg21567404 chr3:27674614 NA 0.57 9.09 0.63 1.94e-15 Dupuytren's disease; TGCT cis rs67311347 1.000 rs10510708 chr3:40404770 A/G cg13683864 chr3:40499215 RPL14 -1.02 -10.8 -0.7 1.43e-19 Renal cell carcinoma; TGCT cis rs6912958 0.712 rs4706294 chr6:88317675 G/C cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -5.2 -0.42 7.9e-7 Monocyte percentage of white cells; TGCT trans rs916888 0.647 rs199523 chr17:44848517 C/A cg22968622 chr17:43663579 NA -1.05 -10.06 -0.67 8.89e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12200560 0.524 rs1413525 chr6:97073096 C/T cg06623918 chr6:96969491 KIAA0776 0.6 5.17 0.42 8.99e-7 Coronary heart disease; TGCT trans rs2727020 0.521 rs7114564 chr11:49571231 C/T cg11707556 chr5:10655725 ANKRD33B 0.41 8.24 0.59 2.06e-13 Coronary artery disease; TGCT cis rs6665290 0.582 rs72764213 chr1:227207391 C/T cg10327440 chr1:227177885 CDC42BPA -0.92 -16.05 -0.82 4.56e-32 Myeloid white cell count; TGCT cis rs7017914 0.967 rs11989553 chr8:71640899 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs7582180 0.629 rs11123826 chr2:100936276 G/T cg14675211 chr2:100938903 LONRF2 -0.5 -4.88 -0.4 3.18e-6 Intelligence (multi-trait analysis); TGCT cis rs12135062 0.851 rs2651926 chr1:3101820 C/T cg00254258 chr1:3105189 PRDM16 -0.36 -5.86 -0.47 3.95e-8 Migraine; TGCT cis rs7666738 0.830 rs35939134 chr4:98980311 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2841277 0.708 rs10083490 chr14:105402418 A/G cg19901468 chr14:105411992 AHNAK2 0.28 5.93 0.47 2.77e-8 Rheumatoid arthritis; TGCT cis rs9467773 0.967 rs6941022 chr6:26553531 T/C cg15659132 chr6:26577336 NA 0.89 13.14 0.76 3.05e-25 Intelligence (multi-trait analysis); TGCT trans rs2970818 0.831 rs2970810 chr12:4608103 A/G cg04106436 chr12:8665373 CLEC4D 0.31 6.81 0.52 3.67e-10 Phosphorus levels; TGCT cis rs9985766 1.000 rs9307863 chr4:151003443 C/T cg05926478 chr4:151174724 DCLK2 -0.24 -4.6 -0.38 1.03e-5 Coronary artery disease;Myocardial infarction; TGCT cis rs11650494 0.908 rs77488129 chr17:47448970 G/A cg08112188 chr17:47440006 ZNF652 1.04 5.31 0.43 4.85e-7 Prostate cancer; TGCT cis rs1577917 0.958 rs12196230 chr6:86519960 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.21 -0.42 7.64e-7 Response to antipsychotic treatment; TGCT trans rs3107575 0.572 rs73169366 chr3:165320307 C/T cg15894581 chr15:63889406 FBXL22 0.88 6.83 0.52 3.32e-10 Morning vs. evening chronotype; TGCT cis rs5750830 0.649 rs4821893 chr22:39797779 G/A cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.577 rs867056 chr6:145784805 A/C cg23711669 chr6:146136114 FBXO30 -0.73 -6.83 -0.52 3.43e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9899728 0.539 rs12940199 chr17:73054759 C/T cg27626185 chr17:73056755 KCTD2 -0.92 -8.01 -0.58 7.17e-13 Alzheimer's disease or small vessel stroke; TGCT cis rs2594989 0.943 rs7622627 chr3:11357419 T/C cg00170343 chr3:11313890 ATG7 0.66 4.87 0.4 3.39e-6 Circulating chemerin levels; TGCT cis rs13191362 0.935 rs13212137 chr6:163010261 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs61990749 0.597 rs11624101 chr14:78138059 G/A cg02301378 chr14:78227641 SNW1;C14orf178 -0.61 -4.45 -0.37 1.89e-5 Fibroblast growth factor basic levels; TGCT cis rs2777491 0.957 rs2015781 chr15:41648967 C/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.46 -0.68 9.68e-19 Ulcerative colitis; TGCT cis rs12497850 0.931 rs12493289 chr3:48905161 G/A cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs12643440 0.538 rs879572 chr4:17148487 G/C cg22650099 chr4:17144496 NA -0.47 -4.78 -0.39 4.83e-6 Metabolite levels (Pyroglutamine); TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg01802117 chr1:53393560 SCP2 -0.39 -4.61 -0.38 1e-5 Monocyte count; TGCT cis rs12500482 0.935 rs12644638 chr4:2413461 C/T cg08330972 chr4:2403930 ZFYVE28 -0.38 -5.35 -0.43 4.15e-7 Cognitive function; TGCT cis rs6570726 0.764 rs9399553 chr6:145873664 A/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg14893161 chr1:205819251 PM20D1 0.55 7.63 0.57 5.31e-12 Menarche (age at onset); TGCT cis rs7089973 0.604 rs7919649 chr10:116609576 T/C cg03647239 chr10:116582469 FAM160B1 0.57 5.48 0.44 2.3e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9549367 0.789 rs2287250 chr13:113889474 C/T cg18105134 chr13:113819100 PROZ 0.35 5.81 0.46 4.91e-8 Platelet distribution width; TGCT cis rs523522 0.962 rs2168319 chr12:120933217 C/T cg27279351 chr12:120934652 DYNLL1 0.77 6.61 0.51 1.02e-9 High light scatter reticulocyte count; TGCT cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs473651 0.935 rs558924 chr2:239339511 A/G cg08773314 chr2:239334832 ASB1 0.45 6.39 0.5 3.05e-9 Multiple system atrophy; TGCT cis rs611744 0.506 rs13280454 chr8:109263240 A/G cg21045802 chr8:109455806 TTC35 0.7 7.05 0.54 1.07e-10 Dupuytren's disease; TGCT cis rs17376456 0.597 rs7728825 chr5:93384594 T/C cg25358565 chr5:93447407 FAM172A -0.62 -5.93 -0.47 2.83e-8 Diabetic retinopathy; TGCT cis rs7172809 0.599 rs74666689 chr15:77786731 C/T cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs7607369 0.526 rs10498060 chr2:219431291 G/A cg02176678 chr2:219576539 TTLL4 -0.52 -5.82 -0.46 4.79e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs4776059 0.959 rs12898644 chr15:52905233 A/G cg25063058 chr15:52860530 ARPP19 0.52 4.73 0.39 6.01e-6 Schizophrenia; TGCT cis rs1371867 0.846 rs2439460 chr8:101312665 C/T cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs6089584 1.000 rs6089583 chr20:60563624 G/A cg13770153 chr20:60521292 NA -0.44 -5.62 -0.45 1.21e-7 Body mass index; TGCT cis rs7524258 0.868 rs1304712 chr1:7270538 C/T cg04342483 chr1:7259290 CAMTA1 -0.3 -4.45 -0.37 1.89e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7659604 0.540 rs116452657 chr4:122674147 A/G cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs9948 0.655 rs62156216 chr2:97405127 C/T cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs28386778 0.863 rs3826341 chr17:61819222 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs6867913 0.709 rs891987 chr5:141467196 A/T cg01169021 chr5:140792918 PCDHGA4;PCDHGA6;PCDHGA9;PCDHGA1;PCDHGA8;PCDHGA5;PCDHGB1;PCDHGA10;PCDHGB4;PCDHGA3;PCDHGA2;PCDHGB6;PCDHGA7;PCDHGB2;PCDHGB5;PCDHGB3 0.39 4.93 0.4 2.6e-6 Asthma; TGCT cis rs733175 0.857 rs7666545 chr4:10012372 C/T cg00071950 chr4:10020882 SLC2A9 0.54 4.54 0.38 1.3e-5 Psychosis and Alzheimer's disease; TGCT cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs981844 1.000 rs17371021 chr4:154664295 A/G cg14289246 chr4:154710475 SFRP2 -0.92 -7.32 -0.55 2.71e-11 Response to statins (LDL cholesterol change); TGCT cis rs1371867 0.641 rs1788209 chr8:101337056 C/T cg06636551 chr8:101224915 SPAG1 -0.45 -6.12 -0.48 1.13e-8 Atrioventricular conduction; TGCT cis rs9611565 0.512 rs132784 chr22:42052363 G/A cg03806693 chr22:41940476 POLR3H 1.1 11.41 0.72 4.6e-21 Vitiligo; TGCT trans rs1814175 0.529 rs10839396 chr11:49852406 G/T cg18944383 chr4:111397179 ENPEP -0.45 -7.0 -0.53 1.45e-10 Height; TGCT cis rs6088590 0.965 rs13040449 chr20:33358901 T/A cg24642439 chr20:33292090 TP53INP2 0.7 6.22 0.49 7.12e-9 Coronary artery disease; TGCT cis rs11673344 0.523 rs10406110 chr19:37650929 G/C cg08039142 chr19:36980659 ZNF566 0.49 4.49 0.37 1.63e-5 Obesity-related traits; TGCT cis rs4253772 0.638 rs6007845 chr22:46718417 A/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.69 -5.31 -0.43 4.82e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs3749237 0.595 rs35701831 chr3:49515000 A/C cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg08280861 chr8:58055591 NA 0.4 4.89 0.4 3.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs4819052 0.851 rs2838844 chr21:46670733 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.82 7.26 0.55 3.65e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1023500 1.000 rs6002552 chr22:42338351 G/A cg04692870 chr22:42525206 CYP2D6 -0.35 -5.21 -0.42 7.53e-7 Schizophrenia; TGCT cis rs7647973 0.566 rs57630346 chr3:49086215 T/C cg07636037 chr3:49044803 WDR6 0.81 6.68 0.51 7.37e-10 Menarche (age at onset); TGCT cis rs858239 0.600 rs10237755 chr7:23131564 A/G cg05602783 chr7:23145260 KLHL7 -0.64 -5.37 -0.43 3.69e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs881375 0.967 rs10435843 chr9:123668033 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.06 0.41 1.49e-6 Rheumatoid arthritis; TGCT trans rs2469997 1.000 rs1599476 chr8:120351800 C/T cg01792902 chr3:178864926 PIK3CA 0.8 6.91 0.53 2.21e-10 Hypertension (SNP x SNP interaction); TGCT cis rs3008870 1.000 rs3008873 chr1:67425770 G/A cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs655029 0.740 rs610077 chr2:31458190 G/A cg14018959 chr2:31480232 EHD3 -0.36 -4.89 -0.4 3.08e-6 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs11190604 1.000 rs11190540 chr10:102202629 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6912958 0.667 rs7746545 chr6:88090225 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.66 6.8 0.52 3.89e-10 Monocyte percentage of white cells; TGCT cis rs2050392 0.799 rs303429 chr10:30708441 C/T cg18806716 chr10:30721971 MAP3K8 -0.47 -5.53 -0.44 1.8e-7 Inflammatory bowel disease; TGCT cis rs4242434 0.819 rs6558173 chr8:22492103 A/C cg03733263 chr8:22462867 KIAA1967 -1.07 -15.28 -0.81 2.69e-30 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs17826219 0.568 rs7213925 chr17:29121634 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg25204440 chr1:209979598 IRF6 0.7 7.45 0.56 1.4e-11 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg24675658 chr1:53192096 ZYG11B -0.85 -10.48 -0.69 8.41e-19 Monocyte count; TGCT cis rs6815814 0.898 rs73236646 chr4:38871385 T/C cg02016764 chr4:38805732 TLR1 -0.39 -5.81 -0.46 4.87e-8 Breast cancer; TGCT cis rs981844 0.753 rs1105491 chr4:154726634 A/C cg14289246 chr4:154710475 SFRP2 1.01 9.4 0.65 3.53e-16 Response to statins (LDL cholesterol change); TGCT cis rs7542091 0.666 rs7537070 chr1:210043565 A/G cg23283495 chr1:209979779 IRF6 0.55 5.47 0.44 2.34e-7 Monobrow; TGCT cis rs9913156 0.515 rs11658808 chr17:4577112 C/T cg00122941 chr17:4613640 ARRB2 -0.77 -7.4 -0.55 1.82e-11 Lymphocyte counts; TGCT cis rs2013441 1.000 rs2526484 chr17:20103760 A/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs2180341 0.814 rs9401958 chr6:127736357 T/G cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs2486012 1.000 rs3120804 chr1:44405214 T/G cg12908607 chr1:44402522 ARTN 0.78 6.04 0.48 1.68e-8 Intelligence (multi-trait analysis); TGCT cis rs1865760 1.000 rs2071297 chr6:25924513 C/G cg16482183 chr6:26056742 HIST1H1C -0.52 -4.67 -0.39 7.83e-6 Height; TGCT cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.68 0.61 1.9e-14 Platelet count; TGCT trans rs3780486 0.846 rs3780490 chr9:33129839 A/G cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs2637266 0.703 rs846635 chr10:78535132 G/A cg18941641 chr10:78392320 NA 0.39 4.67 0.39 7.62e-6 Pulmonary function; TGCT cis rs9534288 0.619 rs6561290 chr13:46682460 A/G cg15192986 chr13:46630673 CPB2 -0.51 -6.11 -0.48 1.17e-8 Blood protein levels; TGCT cis rs12497850 0.931 rs9846123 chr3:49088112 C/T cg05785598 chr3:49045655 WDR6 -0.36 -4.77 -0.39 5.17e-6 Parkinson's disease; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg09033563 chr22:24373618 LOC391322 -0.52 -5.23 -0.43 6.88e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1570884 0.890 rs7333969 chr13:50123317 C/T cg08779649 chr13:50194554 NA 0.33 5.25 0.43 6.42e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs3796352 0.667 rs11720228 chr3:52877270 G/A cg15956490 chr3:53032818 SFMBT1 0.57 5.25 0.43 6.25e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs902774 0.530 rs11834907 chr12:53350985 C/T cg05393297 chr12:53359155 NA -0.84 -5.35 -0.43 4.06e-7 Prostate cancer; TGCT cis rs7666738 0.830 rs1025204 chr4:99023441 G/A cg17366294 chr4:99064904 C4orf37 0.7 7.18 0.54 5.7e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6430585 1.000 rs6430585 chr2:136506927 A/C cg07169764 chr2:136633963 MCM6 -0.88 -7.8 -0.57 2.16e-12 Corneal structure; TGCT cis rs908922 0.651 rs564107 chr1:152519295 C/T cg20991723 chr1:152506922 NA 0.45 6.09 0.48 1.33e-8 Hair morphology; TGCT cis rs367615 0.918 rs10054960 chr5:108866448 C/A cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1451375 0.698 rs11238214 chr7:50636018 A/G cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs7843479 0.509 rs899428 chr8:21770763 T/C cg17168535 chr8:21777572 XPO7 0.77 7.4 0.55 1.81e-11 Mean corpuscular volume; TGCT cis rs514406 0.668 rs520281 chr1:53365235 G/C cg16325326 chr1:53192061 ZYG11B 0.52 5.84 0.46 4.24e-8 Monocyte count; TGCT cis rs9372498 0.505 rs9320655 chr6:118830981 T/C cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs78487399 0.831 rs12469373 chr2:43829191 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs17471911 0.581 rs1344214 chr10:100758587 A/G cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs6688613 0.685 rs11579987 chr1:166889364 C/G cg07049167 chr1:166818506 POGK -0.27 -5.74 -0.46 6.86e-8 Refractive astigmatism; TGCT cis rs72945132 0.882 rs3133179 chr11:70187574 T/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs854765 0.663 rs1052299 chr17:17750419 A/G cg04398451 chr17:18023971 MYO15A 0.3 4.59 0.38 1.09e-5 Total body bone mineral density; TGCT cis rs8077889 0.956 rs4792910 chr17:41840229 T/C cg26893861 chr17:41843967 DUSP3 1.08 13.44 0.77 5.71e-26 Triglycerides; TGCT cis rs2836633 0.929 rs4514962 chr21:40041753 C/T cg12884169 chr21:40033163 ERG 0.45 4.85 0.4 3.69e-6 Coronary artery disease; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs13115356 chr4:98933171 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs7819412 0.527 rs7821914 chr8:10805015 A/G cg15556689 chr8:8085844 FLJ10661 -0.79 -7.29 -0.55 3.22e-11 Triglycerides; TGCT cis rs8072100 1.000 rs11650372 chr17:45721795 G/A cg08085267 chr17:45401833 C17orf57 -0.47 -5.13 -0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs791357 0.501 rs791362 chr5:173212127 A/T cg04561637 chr5:172480106 NA -0.25 -4.75 -0.39 5.63e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs1903068 0.853 rs9312656 chr4:56002972 C/G cg16572876 chr4:56024045 NA 0.42 4.79 0.39 4.75e-6 Endometriosis; TGCT cis rs10875746 0.729 rs11168357 chr12:48412138 G/A cg20731937 chr12:48336164 NA 0.6 4.99 0.41 1.97e-6 Longevity (90 years and older); TGCT cis rs6598955 0.671 rs10493030 chr1:26561856 T/C cg04990556 chr1:26633338 UBXN11 0.64 5.11 0.42 1.19e-6 Obesity-related traits; TGCT cis rs7474896 0.515 rs662928 chr10:38316216 G/T cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs2153535 0.580 rs9328479 chr6:8519646 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9527 0.637 rs7085104 chr10:104628873 A/G cg04362960 chr10:104952993 NT5C2 0.56 4.86 0.4 3.52e-6 Arsenic metabolism; TGCT cis rs10875746 0.903 rs11168401 chr12:48481519 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs12477438 0.520 rs4850897 chr2:99768419 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs877282 0.898 rs11253343 chr10:765117 C/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs10504229 0.593 rs113184543 chr8:58042950 A/G cg08280861 chr8:58055591 NA 0.35 4.92 0.4 2.72e-6 Developmental language disorder (linguistic errors); TGCT cis rs12142240 0.698 rs6703669 chr1:46862555 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs7772486 0.875 rs2748483 chr6:146335560 A/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.9 -0.4 2.96e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs380904 0.926 rs7842979 chr8:144601896 T/G cg09317036 chr8:144635547 GSDMD 0.51 4.71 0.39 6.41e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs2204008 0.837 rs7315255 chr12:37949279 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs7605378 1.000 rs769957 chr2:200695524 A/C cg17644776 chr2:200775616 C2orf69 0.28 5.25 0.43 6.44e-7 Osteoporosis; TGCT cis rs7845219 0.544 rs4735332 chr8:95923660 C/T cg13393036 chr8:95962371 TP53INP1 -0.44 -5.11 -0.42 1.18e-6 Type 2 diabetes; TGCT cis rs13191362 1.000 rs66594243 chr6:163169024 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.14 9.35 0.64 4.74e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7255045 0.752 rs55730975 chr19:12973039 G/A cg23899408 chr19:12877188 HOOK2 -0.61 -4.99 -0.41 1.97e-6 Mean corpuscular volume; TGCT cis rs778371 0.723 rs283470 chr2:233656918 G/A cg08000102 chr2:233561755 GIGYF2 0.69 8.08 0.59 4.87e-13 Schizophrenia; TGCT cis rs4699052 0.928 rs2126473 chr4:104141533 G/C cg16532752 chr4:104119610 CENPE -0.59 -5.56 -0.45 1.56e-7 Testicular germ cell tumor; TGCT cis rs3806843 0.576 rs246005 chr5:140339884 A/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs9926296 0.548 rs6500439 chr16:89808275 A/C cg03388025 chr16:89894329 SPIRE2 0.49 8.32 0.6 1.38e-13 Vitiligo; TGCT cis rs1008375 1.000 rs6848360 chr4:17634442 G/T cg18681998 chr4:17616180 MED28 1.07 11.98 0.73 1.97e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7824557 0.564 rs1435275 chr8:11235735 T/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.48e-10 Retinal vascular caliber; TGCT cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs1865760 0.566 rs9295688 chr6:26084217 G/A cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs941408 0.515 rs1736188 chr19:2782368 A/G cg06609049 chr19:2785107 THOP1 1.14 13.05 0.76 4.95e-25 Total cholesterol levels; TGCT cis rs4595586 0.545 rs7973338 chr12:39380704 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs56104184 0.779 rs17206693 chr19:49360252 C/G cg15549821 chr19:49342101 PLEKHA4 -0.78 -9.08 -0.63 2.09e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs17331151 0.573 rs77223362 chr3:52865125 G/A cg15956490 chr3:53032818 SFMBT1 0.46 5.75 0.46 6.57e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9911578 1.000 rs9907499 chr17:56949044 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs7147624 1.000 rs10135969 chr14:65982345 C/T cg03016385 chr14:66212404 NA -0.49 -7.11 -0.54 8.13e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2797160 0.935 rs12717178 chr6:126016499 G/A cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs929354 0.772 rs6459741 chr7:157014553 G/T cg05182265 chr7:156933206 UBE3C -0.4 -9.08 -0.63 2.11e-15 Body mass index; TGCT cis rs7926906 1.000 rs4304731 chr11:90523785 C/A cg26138821 chr11:89956704 CHORDC1 -0.53 -5.69 -0.46 8.52e-8 Intelligence (multi-trait analysis); TGCT cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.61 -5.48 -0.44 2.27e-7 Bipolar disorder; TGCT cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg09222892 chr1:25734099 RHCE -0.43 -7.07 -0.54 1.02e-10 Erythrocyte sedimentation rate; TGCT cis rs7666738 0.830 rs17550630 chr4:99008332 G/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3784262 0.669 rs4646559 chr15:58354258 A/G cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6582630 0.519 rs4436613 chr12:38293653 T/C cg26384229 chr12:38710491 ALG10B 0.82 7.23 0.54 4.32e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs11711311 0.911 rs9831422 chr3:113398195 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.8 -7.16 -0.54 6.18e-11 IgG glycosylation; TGCT cis rs1008375 0.966 rs4698638 chr4:17632988 G/C cg16339924 chr4:17578868 LAP3 0.66 5.49 0.44 2.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2066819 1.000 rs78121408 chr12:56684798 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs1461503 0.932 rs7944492 chr11:122838745 G/T cg27398637 chr11:122830231 C11orf63 -0.43 -5.28 -0.43 5.68e-7 Menarche (age at onset); TGCT cis rs6684514 1.000 rs11264464 chr1:156250887 T/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs137699 0.695 rs137653 chr22:39732171 A/G cg24399712 chr22:39784796 NA 0.66 5.77 0.46 5.88e-8 IgG glycosylation; TGCT cis rs28785552 1.000 rs28785552 chr19:53234161 G/A cg22067481 chr19:53234126 ZNF611 -0.51 -7.5 -0.56 1.09e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs75229567 0.618 rs11177849 chr12:70182473 C/T cg10114359 chr12:70132523 RAB3IP -1.35 -6.68 -0.51 7.19e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs614226 0.935 rs17431717 chr12:120912210 G/A cg01236616 chr12:121019343 POP5 -1.2 -11.78 -0.73 5.83e-22 Type 1 diabetes nephropathy; TGCT cis rs8084125 0.832 rs62105175 chr18:74948498 T/C cg07390210 chr18:74961196 GALR1 0.36 4.46 0.37 1.85e-5 Obesity-related traits; TGCT cis rs651907 0.535 rs17347156 chr3:101504674 G/A cg12386194 chr3:101231763 SENP7 0.46 4.5 0.37 1.57e-5 Colorectal cancer; TGCT cis rs11585357 0.895 rs72633812 chr1:17623140 T/C cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs317689 0.918 rs689415 chr12:69738139 A/G cg14784868 chr12:69753453 YEATS4 -0.53 -4.45 -0.37 1.9e-5 Response to diuretic therapy; TGCT cis rs7120118 0.517 rs61896015 chr11:47279928 C/A cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.16e-7 HDL cholesterol; TGCT cis rs7572733 0.515 rs11887138 chr2:198805838 T/A cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs7100689 0.784 rs10887838 chr10:82161380 G/A cg01528321 chr10:82214614 TSPAN14 0.87 8.71 0.62 1.62e-14 Post bronchodilator FEV1; TGCT cis rs9926296 0.605 rs886951 chr16:89836865 A/G cg03388025 chr16:89894329 SPIRE2 0.49 8.53 0.61 4.4e-14 Vitiligo; TGCT cis rs7618915 0.547 rs2286800 chr3:52778051 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs2404602 0.684 rs11072602 chr15:76873467 T/C cg23625390 chr15:77176239 SCAPER -0.37 -4.67 -0.39 7.71e-6 Blood metabolite levels; TGCT cis rs1062177 0.855 rs6884630 chr5:151268997 A/T cg12924095 chr5:151150029 G3BP1 0.33 4.46 0.37 1.82e-5 Preschool internalizing problems; TGCT cis rs3862030 0.836 rs12771867 chr10:104246691 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -4.61 -0.38 1e-5 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs75686122 0.772 rs76135007 chr8:104570286 T/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs6433895 1.000 rs34714467 chr2:182017987 G/A cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT cis rs986417 0.688 rs1950317 chr14:61022789 T/G cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs6909279 0.648 rs6919923 chr6:151849670 T/C cg14416726 chr6:151773293 C6orf211;RMND1 0.64 5.79 0.46 5.32e-8 Bone mineral density; TGCT cis rs9296092 0.538 rs9296094 chr6:33520064 A/G cg13560919 chr6:33536144 NA -0.2 -4.64 -0.38 8.68e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs11077998 0.935 rs11653926 chr17:80484953 G/A cg10255544 chr17:80519551 FOXK2 0.23 4.48 0.37 1.69e-5 Reticulocyte fraction of red cells; TGCT cis rs1577917 1.000 rs1415753 chr6:86753074 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.2 -0.42 8.12e-7 Response to antipsychotic treatment; TGCT cis rs926938 0.618 rs360675 chr1:115490918 T/C cg12756093 chr1:115239321 AMPD1 0.4 5.97 0.47 2.29e-8 Autism; TGCT cis rs6121246 0.529 rs112367115 chr20:30178627 G/A cg21427119 chr20:30132790 HM13 -0.44 -6.39 -0.5 3.11e-9 Mean corpuscular hemoglobin; TGCT cis rs4566357 1.000 rs4536647 chr2:227921977 A/G cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg10150615 chr22:24372951 LOC391322 -0.89 -10.54 -0.69 6e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg06108461 chr20:60628389 TAF4 0.68 9.61 0.65 1.12e-16 Body mass index; TGCT cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg16497277 chr3:49208875 KLHDC8B -0.49 -4.48 -0.37 1.68e-5 Parkinson's disease; TGCT cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg12311346 chr5:56204834 C5orf35 -0.63 -6.41 -0.5 2.73e-9 Initial pursuit acceleration; TGCT cis rs9393777 0.513 rs7754159 chr6:26620312 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.55 -5.08 -0.42 1.35e-6 Intelligence (multi-trait analysis); TGCT cis rs9527 0.590 rs726010 chr10:104841977 C/T cg15744005 chr10:104629667 AS3MT -0.45 -5.24 -0.43 6.64e-7 Arsenic metabolism; TGCT cis rs10431058 0.965 rs1939895 chr11:107483469 C/T cg18204760 chr11:107461044 ELMOD1;LOC643923 0.68 6.57 0.51 1.22e-9 Common traits (Other); TGCT cis rs509477 1.000 rs7245165 chr18:32567007 C/A cg23791764 chr18:32556832 MAPRE2 0.55 4.6 0.38 1.04e-5 Cerebrospinal fluid AB1-42 levels; TGCT cis rs7267979 0.932 rs417110 chr20:25458297 T/C cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7923609 1.000 rs10822161 chr10:65118203 G/A cg08743896 chr10:65200160 JMJD1C -0.34 -4.46 -0.37 1.78e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs2046867 0.908 rs2322613 chr3:72819453 A/C cg25664220 chr3:72788482 NA -0.54 -6.79 -0.52 4.1e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7786808 0.525 rs10253961 chr7:158194858 G/A cg01191920 chr7:158217561 PTPRN2 0.36 5.16 0.42 9.41e-7 Obesity-related traits; TGCT cis rs12220898 0.749 rs7913006 chr10:50483043 G/T cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs801193 0.660 rs2659914 chr7:66156914 C/T cg11764359 chr7:65958608 NA 0.59 5.09 0.42 1.28e-6 Aortic root size; TGCT cis rs10883723 0.810 rs12162 chr10:104240498 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 5.78 0.46 5.63e-8 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9500256 1.000 rs9500256 chr6:58308955 C/T cg16251399 chr6:58287822 GUSBL2 0.66 6.07 0.48 1.43e-8 Eosinophilic esophagitis (pediatric); TGCT cis rs7727544 0.548 rs4705938 chr5:131694077 A/G cg24060327 chr5:131705240 SLC22A5 -0.55 -5.83 -0.46 4.49e-8 Blood metabolite levels; TGCT cis rs6088580 0.634 rs6059860 chr20:33063830 A/C cg08999081 chr20:33150536 PIGU 0.29 5.6 0.45 1.31e-7 Glomerular filtration rate (creatinine); TGCT cis rs3812831 0.695 rs422149 chr13:114931086 T/G cg15513719 chr13:114904418 NA 0.38 4.65 0.39 8.31e-6 Schizophrenia; TGCT cis rs4455778 0.659 rs11185619 chr7:49017248 A/G cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs9650657 0.737 rs4504595 chr8:10655505 A/G cg27411982 chr8:10470053 RP1L1 -0.24 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs6061231 0.631 rs2427310 chr20:60969929 C/G cg15674680 chr20:60982522 CABLES2 0.57 4.94 0.41 2.47e-6 Colorectal cancer; TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg07157834 chr1:205819609 PM20D1 0.45 7.27 0.55 3.51e-11 Menarche (age at onset); TGCT cis rs4819052 0.851 rs58644915 chr21:46669912 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 6.96 0.53 1.71e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg25660036 chr4:7070649 GRPEL1 -0.62 -5.35 -0.43 4.04e-7 Monocyte percentage of white cells; TGCT cis rs9291683 0.526 rs6827785 chr4:10018205 C/T cg11266682 chr4:10021025 SLC2A9 0.69 9.11 0.63 1.78e-15 Bone mineral density; TGCT cis rs6684514 1.000 rs12121805 chr1:156257876 A/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs826838 0.967 rs1684415 chr12:39130099 T/C cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs7647973 1.000 rs1464569 chr3:49460350 A/G cg05785598 chr3:49045655 WDR6 0.37 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs17001868 0.614 rs61467436 chr22:40736713 T/C cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs938554 0.571 rs4144 chr4:10016322 T/C cg11266682 chr4:10021025 SLC2A9 0.58 5.48 0.44 2.24e-7 Blood metabolite levels; TGCT cis rs8072100 0.967 rs11079784 chr17:45702280 A/G cg08085267 chr17:45401833 C17orf57 0.43 4.68 0.39 7.53e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9900497 0.604 rs12949049 chr17:19653310 A/G cg21692194 chr17:19436881 SLC47A1 0.26 4.5 0.37 1.56e-5 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs10242455 0.702 rs57832867 chr7:98966396 C/T cg13560068 chr7:99070416 ZNF789 1.09 4.66 0.39 8.13e-6 Blood metabolite levels; TGCT cis rs1801251 1.000 rs71421663 chr2:233619131 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg20637647 chr7:64974828 NA 0.9 5.29 0.43 5.42e-7 Diabetic kidney disease; TGCT cis rs140365914 1 rs140365914 chr7:155106570 C/T cg04811098 chr7:155088454 INSIG1 0.32 4.96 0.41 2.23e-6 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13256369 1.000 rs10098234 chr8:8576692 G/A cg17143192 chr8:8559678 CLDN23 0.62 5.83 0.46 4.47e-8 Obesity-related traits; TGCT trans rs10506458 1.000 rs73128794 chr12:63445313 C/T cg22491629 chr6:157744540 C6orf35 -0.96 -8.34 -0.6 1.21e-13 Hemostatic factors and hematological phenotypes; TGCT cis rs2486288 0.656 rs8039354 chr15:45551756 A/G cg14582100 chr15:45693742 SPATA5L1 0.46 5.59 0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs1577917 0.917 rs13196576 chr6:86534066 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT trans rs1496653 0.602 rs34171096 chr3:23529279 C/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs7100689 0.646 rs10887808 chr10:82137367 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs7666738 0.716 rs9994641 chr4:99101605 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.53 0.44 1.83e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2594989 0.831 rs13324245 chr3:11570769 T/G cg00170343 chr3:11313890 ATG7 -0.62 -4.56 -0.38 1.19e-5 Circulating chemerin levels; TGCT cis rs3806843 0.966 rs10053945 chr5:140160127 C/T cg19875535 chr5:140030758 IK 0.37 6.17 0.48 8.88e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs3796352 1.000 rs750474 chr3:53085280 A/C cg27565382 chr3:53032988 SFMBT1 0.39 4.49 0.37 1.59e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs12681287 0.640 rs28561640 chr8:87425638 G/A cg27223183 chr8:87520930 FAM82B 0.89 6.36 0.5 3.45e-9 Caudate activity during reward; TGCT cis rs11677370 0.561 rs12711973 chr2:3825339 C/G cg17052675 chr2:3827356 NA -0.42 -7.68 -0.57 4.22e-12 Type 2 diabetes; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg23156509 chr2:114033830 PAX8;LOC440839 0.32 4.92 0.4 2.71e-6 Lymphocyte counts; TGCT cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg03188948 chr7:1209495 NA 0.44 5.79 0.46 5.49e-8 Longevity;Endometriosis; TGCT cis rs7772486 0.875 rs9322044 chr6:146369608 T/C cg05347473 chr6:146136440 FBXO30 0.57 5.46 0.44 2.47e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6121246 0.909 rs1075698 chr20:30387992 G/C cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs3751972 0.590 rs34371806 chr17:26264057 T/C cg02948944 chr17:26242737 NA -0.46 -5.71 -0.46 7.8e-8 Fractional exhaled nitric oxide (childhood); TGCT cis rs875971 0.798 rs12698522 chr7:65967341 T/C cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs7017914 0.905 rs2732108 chr8:71926099 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs56104184 0.775 rs73061695 chr19:49399988 T/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2204008 0.603 rs4397954 chr12:38089157 T/C cg13010199 chr12:38710504 ALG10B 0.65 5.15 0.42 9.75e-7 Bladder cancer; TGCT cis rs7917772 0.503 rs11191330 chr10:104306160 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 8.59 0.61 3.11e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8017423 0.607 rs10142482 chr14:90848280 G/T cg04374321 chr14:90722782 PSMC1 -0.49 -4.54 -0.38 1.31e-5 Mortality in heart failure; TGCT cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs7095607 0.813 rs960772 chr10:69931674 A/G cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.72e-6 Lung function (FVC); TGCT cis rs4253772 0.530 rs9615961 chr22:46754993 T/C cg24881330 chr22:46731750 TRMU 1.06 5.5 0.44 2.08e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg24549020 chr5:56110836 MAP3K1 0.72 6.03 0.48 1.73e-8 Initial pursuit acceleration; TGCT cis rs62103177 0.810 rs62096746 chr18:77619556 T/A cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs78366141 0.649 rs76401410 chr4:89694624 A/G cg01026744 chr4:89619053 NAP1L5;HERC3 1.26 5.58 0.45 1.43e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs76878669 0.561 rs4630308 chr11:66162587 G/A cg18002602 chr11:66138449 SLC29A2 0.53 6.57 0.51 1.22e-9 Educational attainment (years of education); TGCT cis rs7551222 0.716 rs4951083 chr1:204582730 A/G cg09150239 chr1:204347429 NA 0.48 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs6951245 0.554 rs11761322 chr7:1151657 A/G cg03188948 chr7:1209495 NA 0.5 5.23 0.43 6.99e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2302464 0.661 rs1807250 chr4:15742592 G/C cg16359663 chr4:15503662 CC2D2A -0.35 -4.73 -0.39 5.96e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs6912958 0.712 rs7746465 chr6:88348996 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs9810089 0.843 rs696081 chr3:136047189 C/T cg12473912 chr3:136751656 NA -0.36 -5.14 -0.42 1.04e-6 Gestational age at birth (child effect); TGCT cis rs11112613 0.775 rs61200462 chr12:105969271 G/A cg03607813 chr12:105948248 NA 0.47 5.66 0.45 1e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs4689388 0.926 rs6446480 chr4:6295565 C/T cg14416269 chr4:6271139 WFS1 0.38 4.89 0.4 3.12e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6582630 0.555 rs11613249 chr12:38519339 T/C cg13010199 chr12:38710504 ALG10B 0.59 4.77 0.39 5.14e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12451471 0.637 rs12452616 chr17:78090081 A/G cg06718696 chr17:78121285 EIF4A3 -0.75 -6.24 -0.49 6.38e-9 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs10254284 1.000 rs6962289 chr7:28161379 C/A cg23620719 chr7:28220237 JAZF1 -0.54 -4.73 -0.39 5.89e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs7523273 0.526 rs2745975 chr1:208013620 C/T cg22525895 chr1:207977042 MIR29B2 -0.53 -9.29 -0.64 6.43e-16 Schizophrenia; TGCT cis rs4722166 0.598 rs4722171 chr7:22785717 A/G cg26061582 chr7:22766209 IL6 0.58 7.32 0.55 2.77e-11 Lung cancer; TGCT cis rs9926296 0.548 rs6500439 chr16:89808275 A/C cg21285383 chr16:89894308 SPIRE2 0.43 6.51 0.5 1.64e-9 Vitiligo; TGCT cis rs877282 0.898 rs35743076 chr10:758991 C/T cg17470449 chr10:769945 NA 0.36 5.32 0.43 4.77e-7 Uric acid levels; TGCT cis rs7666738 0.830 rs11947027 chr4:99005941 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6918586 0.658 rs198803 chr6:26135052 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.67 -6.44 -0.5 2.42e-9 Schizophrenia; TGCT cis rs6746896 0.959 rs2271893 chr2:97405440 G/A cg26085987 chr2:97230376 NA 0.2 4.82 0.4 4.14e-6 Bipolar disorder; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg01585852 chr22:24235823 MIF -0.22 -4.82 -0.4 4.16e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9399137 0.507 rs35571217 chr6:135290355 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs548181 0.577 rs569766 chr11:125532369 G/A cg03464685 chr11:125439445 EI24 1.27 9.56 0.65 1.46e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12210905 0.920 rs6911234 chr6:27086859 T/A cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs514406 0.505 rs835609 chr1:53170494 T/C cg01802117 chr1:53393560 SCP2 -0.43 -4.91 -0.4 2.79e-6 Monocyte count; TGCT cis rs2224391 0.628 rs2773314 chr6:5253800 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.99 -6.43 -0.5 2.46e-9 Height; TGCT cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg11375102 chr16:1583810 IFT140;TMEM204 -0.31 -5.53 -0.44 1.78e-7 Coronary artery disease; TGCT cis rs7412746 0.611 rs111842513 chr1:150712926 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.87 0.4 3.27e-6 Melanoma; TGCT cis rs2153535 0.580 rs9393021 chr6:8466123 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9486719 0.947 rs9398072 chr6:96911304 T/C cg06623918 chr6:96969491 KIAA0776 0.96 8.88 0.62 6.44e-15 Migraine;Coronary artery disease; TGCT cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg06238570 chr21:40685208 BRWD1 -0.62 -6.3 -0.49 4.82e-9 Menarche (age at onset); TGCT cis rs9644630 0.932 rs4921653 chr8:19359853 C/T cg01280390 chr8:19363452 CSGALNACT1 0.27 4.7 0.39 6.7e-6 Oropharynx cancer; TGCT cis rs941408 0.515 rs7253128 chr19:2776982 C/T cg06609049 chr19:2785107 THOP1 1.11 12.98 0.76 7.5e-25 Total cholesterol levels; TGCT cis rs3780378 1.000 rs1328918 chr9:5107394 A/G cg02405213 chr9:5042618 JAK2 -0.64 -8.35 -0.6 1.15e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7100689 0.542 rs7096715 chr10:82195949 T/C cg01528321 chr10:82214614 TSPAN14 0.69 5.77 0.46 6.09e-8 Post bronchodilator FEV1; TGCT cis rs13256369 0.755 rs12550057 chr8:8562268 G/A cg18904891 chr8:8559673 CLDN23 0.57 5.29 0.43 5.35e-7 Obesity-related traits; TGCT cis rs7944584 0.588 rs2697923 chr11:47363215 G/T cg20307385 chr11:47447363 PSMC3 -0.79 -7.99 -0.58 8.1e-13 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs10791323 0.569 rs10750552 chr11:133740141 A/C cg03690763 chr11:133734501 NA 0.29 5.12 0.42 1.16e-6 Childhood ear infection; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg09333631 chr3:44802604 KIF15;KIAA1143 -0.41 -4.47 -0.37 1.71e-5 Depressive symptoms; TGCT cis rs8038465 0.615 rs6495076 chr15:73982965 G/A cg15420318 chr15:73925796 NPTN 0.67 7.42 0.55 1.62e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4891159 0.790 rs77878087 chr18:74116337 G/A cg24786174 chr18:74118243 ZNF516 -0.62 -9.41 -0.65 3.36e-16 Longevity; TGCT cis rs75059851 0.756 rs2000853 chr11:133838417 A/G cg14047540 chr11:133829660 NA -0.53 -5.34 -0.43 4.37e-7 Schizophrenia; TGCT cis rs3796619 1.000 rs55741287 chr4:1094670 T/C cg27284194 chr4:1044797 NA 0.47 4.45 0.37 1.9e-5 Recombination rate (males); TGCT cis rs763014 0.593 rs28455838 chr16:681966 T/C cg09263875 chr16:632152 PIGQ 0.31 6.88 0.53 2.64e-10 Height; TGCT cis rs7104764 1.000 rs6598069 chr11:240664 T/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs1505368 0.817 rs1283310 chr2:213273891 A/G cg20637307 chr2:213403960 ERBB4 0.52 4.85 0.4 3.7e-6 Symmetrical dimethylarginine levels; TGCT cis rs13326165 0.760 rs28481563 chr3:52417638 T/C cg27565382 chr3:53032988 SFMBT1 0.38 5.06 0.41 1.5e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7647973 0.769 rs6446204 chr3:49034879 T/C cg07636037 chr3:49044803 WDR6 0.82 6.59 0.51 1.12e-9 Menarche (age at onset); TGCT cis rs2271316 0.587 rs11078659 chr17:6903944 G/A cg19536664 chr17:6899085 ALOX12 0.32 5.06 0.41 1.46e-6 Blood metabolite levels; TGCT cis rs9611565 0.592 rs57102627 chr22:41987627 T/C cg03806693 chr22:41940476 POLR3H -1.01 -10.2 -0.68 4.07e-18 Vitiligo; TGCT cis rs492146 0.729 rs426013 chr6:52840745 T/C cg06706454 chr6:52930286 FBXO9 -0.51 -4.64 -0.38 8.63e-6 Epilepsy (remission after treatment); TGCT cis rs921968 0.509 rs626432 chr2:219355658 C/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs1552244 0.935 rs35515831 chr3:10071362 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs346785 0.666 rs8072620 chr17:74283253 A/G cg09812376 chr17:74270190 QRICH2 -0.36 -5.38 -0.44 3.56e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs9913156 0.793 rs56020376 chr17:4560909 A/G cg00122941 chr17:4613640 ARRB2 0.87 7.38 0.55 1.95e-11 Lymphocyte counts; TGCT cis rs4455778 0.659 rs67170454 chr7:49027518 A/G cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs2447097 0.904 rs2429914 chr17:2277668 T/C cg27406664 chr17:2294951 MNT 0.26 5.22 0.42 7.44e-7 Autism spectrum disorder; TGCT cis rs9486715 0.830 rs4425602 chr6:96893906 G/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs9325144 0.647 rs61931899 chr12:38892422 A/G cg26384229 chr12:38710491 ALG10B -0.59 -5.48 -0.44 2.28e-7 Morning vs. evening chronotype; TGCT cis rs13424612 1.000 rs7590071 chr2:240900947 G/C cg26363272 chr2:240904871 NDUFA10 0.31 5.13 0.42 1.08e-6 Odorant perception (isobutyraldehyde); TGCT cis rs2887571 0.955 rs11061818 chr12:1637111 G/A cg01940102 chr12:1095972 NA 0.25 4.66 0.39 8.17e-6 Bone mineral density; TGCT cis rs6964587 0.869 rs10276682 chr7:91486070 G/A cg17063962 chr7:91808500 NA -0.85 -9.05 -0.63 2.54e-15 Breast cancer; TGCT cis rs7666738 0.546 rs11097591 chr4:98910173 G/A cg17366294 chr4:99064904 C4orf37 0.65 5.98 0.47 2.24e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9443189 0.526 rs775060 chr6:76373567 G/A cg01950844 chr6:76311363 SENP6 -1.0 -6.14 -0.48 1.01e-8 Prostate cancer; TGCT cis rs1372520 0.684 rs2619355 chr4:90748374 A/C cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs1541995 0.789 rs35717415 chr15:96237165 C/T cg00882281 chr15:96346592 NA 0.3 4.63 0.38 9.12e-6 Photic sneeze reflex; TGCT cis rs7659604 0.540 rs67150579 chr4:122704331 T/A cg06713675 chr4:122721982 EXOSC9 0.38 4.7 0.39 6.8e-6 Type 2 diabetes; TGCT cis rs10514758 0.744 rs72947727 chr3:114889697 C/G cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs6121246 0.567 rs7266471 chr20:30220599 T/A cg18721089 chr20:30220636 NA -0.65 -6.84 -0.52 3.17e-10 Mean corpuscular hemoglobin; TGCT cis rs6582630 0.555 rs7978749 chr12:38527141 G/T cg13010199 chr12:38710504 ALG10B 0.61 4.9 0.4 2.91e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg02458000 chr6:26745757 NA 0.51 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs4664308 0.935 rs6744567 chr2:160933781 C/G cg03641300 chr2:160917029 PLA2R1 -0.28 -6.83 -0.52 3.43e-10 Idiopathic membranous nephropathy; TGCT cis rs7945705 0.774 rs6486060 chr11:9024630 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.52 5.76 0.46 6.22e-8 Hemoglobin concentration; TGCT cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg18402987 chr7:1209562 NA 0.74 6.42 0.5 2.6e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs56104184 0.830 rs55966626 chr19:49342396 G/T cg17863274 chr19:49399704 TULP2 -0.48 -6.07 -0.48 1.44e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs12599106 0.624 rs2173885 chr16:34992749 G/A cg26668828 chr6:292823 DUSP22 -0.84 -8.7 -0.62 1.71e-14 Menopause (age at onset); TGCT cis rs10791323 0.582 rs2723613 chr11:133706696 G/A cg15485101 chr11:133734466 NA 0.41 5.17 0.42 9.11e-7 Childhood ear infection; TGCT cis rs2455799 0.613 rs2470538 chr3:15717124 G/C cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.65e-6 Mean platelet volume; TGCT cis rs7666738 0.830 rs6851253 chr4:99029980 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7829975 0.545 rs13261926 chr8:8551610 T/C cg15556689 chr8:8085844 FLJ10661 -0.57 -4.89 -0.4 3.01e-6 Mood instability; TGCT cis rs2797160 1.000 rs2747719 chr6:126009214 C/T cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.43 4.84 0.4 3.75e-6 Lymphocyte counts; TGCT cis rs7552404 0.727 rs5745427 chr1:76332637 C/A cg03433033 chr1:76189801 ACADM -0.59 -5.97 -0.47 2.34e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4294134 0.608 rs11766433 chr7:135243056 A/G cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs9400467 0.537 rs78080415 chr6:111537016 T/C cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs7769051 0.711 rs7758703 chr6:133085417 T/C cg22852734 chr6:133119734 C6orf192 1.22 6.68 0.51 7.22e-10 Type 2 diabetes nephropathy; TGCT cis rs11098499 0.954 rs6834796 chr4:120414693 A/C cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs10751667 0.643 rs7395613 chr11:933873 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs9308731 1.000 rs6746608 chr2:111892984 C/T cg04202892 chr2:111875749 ACOXL -0.43 -4.62 -0.38 9.37e-6 Chronic lymphocytic leukemia; TGCT cis rs6684514 1.000 rs2296375 chr1:156309372 G/C cg20302342 chr1:156215951 PAQR6 0.36 4.69 0.39 7.06e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6750047 0.585 rs62136319 chr2:38272950 G/A cg07380506 chr2:38303506 CYP1B1 0.59 5.36 0.43 3.84e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs1008375 1.000 rs4698198 chr4:17656536 G/A cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9393777 0.513 rs9393739 chr6:26646966 T/G cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg11502198 chr6:26597334 ABT1 0.55 4.89 0.4 3.05e-6 Intelligence (multi-trait analysis); TGCT cis rs3862435 0.764 rs2601200 chr15:90955177 C/T cg14166756 chr15:90894880 ZNF774 -0.29 -4.68 -0.39 7.31e-6 Response to exercise (triglyceride level interaction); TGCT cis rs6840360 0.837 rs4696294 chr4:152713089 C/A cg22705602 chr4:152727874 NA 0.25 4.57 0.38 1.17e-5 Intelligence (multi-trait analysis); TGCT cis rs611744 0.967 rs596245 chr8:109240822 G/A cg21045802 chr8:109455806 TTC35 0.51 4.71 0.39 6.61e-6 Dupuytren's disease; TGCT cis rs8056742 0.643 rs55914162 chr16:85063037 T/G cg00229868 chr16:85520891 NA 0.42 5.17 0.42 9.19e-7 Amyotrophic lateral sclerosis; TGCT cis rs4595586 0.525 rs7313120 chr12:39388027 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2274273 0.712 rs6572999 chr14:55527374 T/C cg01923255 chr14:55878535 KIAA0831 0.57 4.89 0.4 3.03e-6 Protein biomarker; TGCT cis rs641525 1 rs641525 chr8:2740502 T/G cg06440275 chr8:2005701 MYOM2 -0.42 -4.8 -0.4 4.52e-6 Emphysema-related traits; TGCT cis rs79976124 0.842 rs74881738 chr6:66621825 T/G cg07460842 chr6:66804631 NA 0.6 5.28 0.43 5.54e-7 Type 2 diabetes; TGCT cis rs116095464 0.558 rs7708182 chr5:234788 C/G cg22857025 chr5:266934 NA -0.34 -6.67 -0.51 7.62e-10 Breast cancer; TGCT trans rs4819388 0.751 rs2838532 chr21:45639866 G/T cg17383793 chr5:52405638 MOCS2 -0.71 -6.73 -0.52 5.65e-10 Celiac disease; TGCT cis rs2980439 0.870 rs2945230 chr8:8109936 A/G cg06636001 chr8:8085503 FLJ10661 0.86 8.11 0.59 4.13e-13 Neuroticism; TGCT cis rs2836974 1.000 rs12710454 chr21:40656919 A/G cg06238570 chr21:40685208 BRWD1 0.59 5.26 0.43 6.2e-7 Cognitive function; TGCT cis rs2439831 0.850 rs28513374 chr15:44125495 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs7568458 0.837 rs35215812 chr2:85792384 G/A cg17127132 chr2:85788382 GGCX 0.73 6.97 0.53 1.64e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9896850 0.551 rs7224668 chr17:79235788 T/C cg27412613 chr17:79183705 AZI1 -0.23 -4.7 -0.39 6.68e-6 Frontotemporal dementia; TGCT cis rs28595532 0.920 rs114390336 chr4:119771452 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs7552404 0.727 rs7521344 chr1:76318325 C/T cg03433033 chr1:76189801 ACADM -0.59 -6.06 -0.48 1.51e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4563143 0.675 rs55976444 chr19:29265214 G/C cg12756686 chr19:29218302 NA 0.77 6.61 0.51 1.01e-9 Methadone dose in opioid dependence; TGCT cis rs981844 0.712 rs11099914 chr4:154743519 C/T cg14289246 chr4:154710475 SFRP2 -1.0 -9.35 -0.64 4.84e-16 Response to statins (LDL cholesterol change); TGCT cis rs10089 1.000 rs6595806 chr5:127499764 A/T cg19767477 chr5:127420684 SLC12A2 -0.43 -4.61 -0.38 9.87e-6 Ileal carcinoids; TGCT cis rs3733585 0.605 rs4697926 chr4:10124567 G/T cg11266682 chr4:10021025 SLC2A9 0.53 6.12 0.48 1.13e-8 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12497850 0.543 rs6446218 chr3:49075513 A/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.58 0.45 1.43e-7 Parkinson's disease; TGCT cis rs2777491 1.000 rs316610 chr15:41752852 C/T cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.07 -0.71 3.15e-20 Ulcerative colitis; TGCT trans rs78438709 0.611 rs80232578 chr10:124232915 C/A cg07989568 chr17:6735152 TEKT1 0.7 6.7 0.52 6.49e-10 Headache; TGCT cis rs2204008 0.591 rs11495396 chr12:38380182 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.72e-11 Bladder cancer; TGCT cis rs15676 0.733 rs2900269 chr9:131569878 G/T cg14578146 chr9:130637464 AK1 -0.25 -4.65 -0.39 8.34e-6 Blood metabolite levels; TGCT cis rs875971 0.558 rs4433015 chr7:65639723 A/C cg00343986 chr7:65444356 GUSB -0.23 -5.08 -0.42 1.33e-6 Aortic root size; TGCT cis rs12477438 0.748 rs7558239 chr2:99640581 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs3087591 0.708 rs2189525 chr17:29668808 C/T cg24425628 chr17:29625626 OMG;NF1 -0.41 -5.78 -0.46 5.8e-8 Hip circumference; TGCT cis rs929354 1.000 rs1182414 chr7:157058363 G/A cg05182265 chr7:156933206 UBE3C 0.32 6.66 0.51 7.99e-10 Body mass index; TGCT cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg18305652 chr10:134549665 INPP5A 0.35 5.69 0.45 8.83e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs514406 0.505 rs431427 chr1:53179094 C/A cg22166914 chr1:53195759 ZYG11B 0.45 8.14 0.59 3.47e-13 Monocyte count; TGCT cis rs9926296 0.535 rs36022917 chr16:89893238 A/G cg05177932 chr16:89631655 NA 0.29 4.93 0.41 2.53e-6 Vitiligo; TGCT cis rs1215050 0.791 rs10856931 chr4:98819306 C/T cg05340658 chr4:99064831 C4orf37 0.45 5.78 0.46 5.8e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11648796 0.721 rs3169403 chr16:769247 G/A cg00908189 chr16:619842 PIGQ 0.8 6.33 0.49 4.04e-9 Height; TGCT cis rs732765 0.734 rs12892937 chr14:75168927 C/T cg06637938 chr14:75390232 RPS6KL1 -0.57 -4.97 -0.41 2.2e-6 Non-small cell lung cancer; TGCT cis rs3806843 1.000 rs12055222 chr5:140165568 T/C cg19875535 chr5:140030758 IK 0.37 6.17 0.48 8.88e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6570726 0.791 rs9322029 chr6:145906683 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.55 -6.53 -0.51 1.5e-9 Alzheimer's disease; TGCT trans rs1814175 0.817 rs4881623 chr11:49804991 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.46 -0.56 1.33e-11 Height; TGCT cis rs35146811 0.844 rs13232115 chr7:99670932 T/C cg22906224 chr7:99728672 NA 0.52 4.52 0.38 1.41e-5 Coronary artery disease; TGCT cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs9818758 0.607 rs67831908 chr3:49313513 T/G cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6430585 0.583 rs76097170 chr2:136593498 C/T cg07169764 chr2:136633963 MCM6 1.18 11.26 0.71 1.11e-20 Corneal structure; TGCT cis rs35306767 0.807 rs34982663 chr10:852521 C/G cg26597838 chr10:835615 NA 0.8 11.8 0.73 5.3e-22 Eosinophil percentage of granulocytes; TGCT cis rs2014572 0.967 rs10421632 chr19:57764770 G/A cg24459738 chr19:57751996 ZNF805 -0.58 -5.7 -0.46 8.38e-8 Hyperactive-impulsive symptoms; TGCT cis rs9393777 0.513 rs9379893 chr6:26584668 A/G cg05738196 chr6:26577821 NA 0.64 4.5 0.37 1.53e-5 Intelligence (multi-trait analysis); TGCT cis rs11249608 0.548 rs34054398 chr5:178458371 A/G cg01312482 chr5:178451176 ZNF879 -0.49 -4.82 -0.4 4.11e-6 Pubertal anthropometrics; TGCT cis rs709400 0.663 rs28444993 chr14:103930564 T/C cg12935359 chr14:103987150 CKB -0.36 -5.47 -0.44 2.43e-7 Body mass index; TGCT cis rs9796 0.870 rs3986311 chr15:41264339 C/G cg18705301 chr15:41695430 NDUFAF1 -0.46 -5.96 -0.47 2.45e-8 Menopause (age at onset); TGCT cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg10074409 chr1:209979377 IRF6 -0.41 -4.48 -0.37 1.68e-5 Monobrow; TGCT cis rs6424115 0.729 rs561733 chr1:24049595 T/G cg15997130 chr1:24165203 NA 0.67 6.31 0.49 4.56e-9 Immature fraction of reticulocytes; TGCT cis rs854765 0.547 rs4365348 chr17:17912548 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.41 0.6 8.09e-14 Total body bone mineral density; TGCT cis rs3008870 0.959 rs2985808 chr1:67367741 T/C cg11518657 chr1:67396239 MIER1 0.53 4.72 0.39 6.16e-6 Lymphocyte percentage of white cells; TGCT cis rs12220898 0.749 rs10857460 chr10:50488542 A/G cg06072769 chr10:50146962 WDFY4 0.36 4.75 0.39 5.51e-6 Inflammatory biomarkers; TGCT cis rs6582630 0.512 rs11181007 chr12:38266700 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1949733 0.666 rs3103070 chr4:8508825 A/G cg13073564 chr4:8508604 NA 0.44 4.69 0.39 7.23e-6 Response to antineoplastic agents; TGCT cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7914558 1.000 rs943038 chr10:104826261 T/C cg15744005 chr10:104629667 AS3MT -0.39 -4.84 -0.4 3.81e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17473412 0.963 rs11740716 chr5:122701234 A/G cg15125798 chr5:122621645 NA -0.59 -5.26 -0.43 6.01e-7 Total body bone mineral density; TGCT cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg00814883 chr7:100076585 TSC22D4 -0.89 -9.03 -0.63 2.76e-15 Platelet count; TGCT cis rs28595532 1.000 rs114039398 chr4:119631627 T/C cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT cis rs2282802 0.711 rs1864970 chr5:139633042 T/C cg01081189 chr5:139537190 NA 0.29 5.18 0.42 8.86e-7 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.626 rs12349785 chr9:5076613 G/C cg02405213 chr9:5042618 JAK2 -0.75 -9.83 -0.66 3.19e-17 Pediatric autoimmune diseases; TGCT cis rs910316 1.000 rs10149880 chr14:75633008 A/G cg08847533 chr14:75593920 NEK9 -0.94 -10.45 -0.68 1.01e-18 Height; TGCT cis rs10507380 0.824 rs9512634 chr13:27920452 C/G cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg00684032 chr4:1343700 KIAA1530 0.23 5.01 0.41 1.79e-6 Obesity-related traits; TGCT cis rs9534288 0.762 rs4941539 chr13:46597067 A/T cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs7824557 0.679 rs7004362 chr8:11135974 G/A cg21775007 chr8:11205619 TDH -0.61 -5.75 -0.46 6.57e-8 Retinal vascular caliber; TGCT cis rs7258465 1.000 rs2303697 chr19:18546678 T/C cg06462663 chr19:18546047 ISYNA1 0.2 4.54 0.38 1.33e-5 Breast cancer; TGCT cis rs17401966 0.540 rs58014725 chr1:10474457 T/A cg19773385 chr1:10388646 KIF1B -0.23 -5.46 -0.44 2.52e-7 Hepatocellular carcinoma; TGCT cis rs1577917 0.958 rs12197463 chr6:86445242 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.17 -0.42 9.02e-7 Response to antipsychotic treatment; TGCT cis rs7267979 1.000 rs2258563 chr20:25273435 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs67311347 1.000 rs2085115 chr3:40497540 G/T cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs67311347 0.713 rs73073505 chr3:40310693 C/T cg13683864 chr3:40499215 RPL14 -0.88 -8.56 -0.61 3.63e-14 Renal cell carcinoma; TGCT cis rs1499614 1.000 rs2141924 chr7:66186246 C/T cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs9611519 0.929 rs9611466 chr22:41426299 A/T cg03806693 chr22:41940476 POLR3H -0.7 -6.22 -0.49 6.88e-9 Neuroticism; TGCT cis rs1862618 0.511 rs2591952 chr5:56120769 T/A cg18230493 chr5:56204884 C5orf35 -0.7 -6.06 -0.48 1.48e-8 Initial pursuit acceleration; TGCT cis rs1005277 0.522 rs1208767 chr10:38042295 G/T cg25427524 chr10:38739819 LOC399744 -0.33 -6.6 -0.51 1.06e-9 Extrinsic epigenetic age acceleration; TGCT cis rs9902453 0.904 rs9897794 chr17:28296327 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 7.11 0.54 8.28e-11 Coffee consumption (cups per day); TGCT cis rs317865 0.867 rs10034143 chr4:16159734 C/T cg04764131 chr4:16228633 TAPT1;FLJ39653 0.71 4.86 0.4 3.43e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs1018836 0.923 rs62526886 chr8:91627676 G/A cg16814680 chr8:91681699 NA -0.86 -9.19 -0.64 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.799 rs2665802 chr17:61995030 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.49 -4.75 -0.39 5.44e-6 Prudent dietary pattern; TGCT cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg08439880 chr3:133502540 NA -0.28 -5.19 -0.42 8.28e-7 Iron status biomarkers; TGCT cis rs35883536 0.626 rs7545966 chr1:101047633 G/A cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs9972944 0.651 rs7222415 chr17:63765137 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.31 -0.43 4.87e-7 Total body bone mineral density; TGCT cis rs9330316 0.632 rs4953760 chr2:110313489 A/C cg25199208 chr2:109402912 CCDC138 -0.42 -4.54 -0.38 1.34e-5 Schizophrenia; TGCT cis rs28595532 0.764 rs17259257 chr4:119778889 C/T cg14228332 chr4:119757509 SEC24D 1.3 6.62 0.51 9.62e-10 Cannabis dependence symptom count; TGCT cis rs2997447 0.761 rs72886625 chr1:26455319 A/G cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs6684514 1.000 rs12023438 chr1:156254358 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs79387448 0.701 rs11465596 chr2:102987093 C/A cg09003973 chr2:102972529 NA 1.44 9.99 0.67 1.31e-17 Gut microbiota (bacterial taxa); TGCT cis rs1552244 1.000 rs9820598 chr3:10117912 C/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg09359103 chr1:154839909 KCNN3 -0.68 -12.57 -0.75 6.97e-24 Prostate cancer; TGCT cis rs7830933 0.780 rs9644033 chr8:23610639 A/T cg04349084 chr8:23602677 NA 0.25 4.89 0.4 3.09e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs769267 0.965 rs2965191 chr19:19453521 T/G cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs1997103 0.871 rs9649855 chr7:55410222 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4665809 1.000 rs6546736 chr2:26293878 C/T cg04944784 chr2:26401820 FAM59B 0.68 6.13 0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs7072216 0.763 rs6584200 chr10:100170037 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.44 -0.37 1.93e-5 Metabolite levels; TGCT cis rs73198271 0.737 rs565203 chr8:8632957 T/C cg06636001 chr8:8085503 FLJ10661 -0.61 -4.62 -0.38 9.37e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs6952808 0.823 rs10950448 chr7:1966492 G/C cg22963979 chr7:1858916 MAD1L1 -0.34 -5.31 -0.43 4.83e-7 Bipolar disorder and schizophrenia; TGCT cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg00431813 chr7:1051703 C7orf50 -0.22 -4.7 -0.39 6.93e-6 Longevity;Endometriosis; TGCT trans rs7824557 0.564 rs2736294 chr8:11234626 T/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.42e-10 Retinal vascular caliber; TGCT cis rs1005277 0.579 rs9418322 chr10:38377296 G/T cg25427524 chr10:38739819 LOC399744 -0.39 -7.9 -0.58 1.31e-12 Extrinsic epigenetic age acceleration; TGCT cis rs2290402 0.536 rs4690336 chr4:867242 A/G cg11315544 chr4:1222440 CTBP1 -0.25 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs7833790 0.676 rs7834555 chr8:82697625 A/G cg17211192 chr8:82754475 SNX16 -0.84 -7.67 -0.57 4.24e-12 Diastolic blood pressure; TGCT cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg09323728 chr8:95962352 TP53INP1 -0.52 -6.59 -0.51 1.12e-9 Type 2 diabetes; TGCT cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.846 rs2439458 chr8:101297984 T/C cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs1801251 0.928 rs737028 chr2:233640750 T/C cg25237894 chr2:233734115 C2orf82 0.32 5.68 0.45 8.93e-8 Coronary artery disease; TGCT cis rs1799949 0.773 rs2137990 chr17:41317896 T/A cg05368731 chr17:41323189 NBR1 -1.05 -11.75 -0.73 6.86e-22 Menopause (age at onset); TGCT cis rs9381040 0.655 rs9381029 chr6:41026453 G/C cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT cis rs12220238 1.000 rs10824084 chr10:75911415 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1577917 0.958 rs12213431 chr6:86500956 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -4.96 -0.41 2.24e-6 Response to antipsychotic treatment; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg04234412 chr22:24373322 LOC391322 -0.87 -10.27 -0.68 2.84e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.82 7.8 0.57 2.2e-12 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg12419862 chr22:24373484 LOC391322 0.81 8.51 0.61 4.7e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4782309 0.544 rs8060579 chr16:88751667 G/C cg27087555 chr16:88793112 FAM38A -0.47 -4.71 -0.39 6.51e-6 Hair color; TGCT cis rs611744 0.647 rs579162 chr8:109254842 A/G cg21045802 chr8:109455806 TTC35 0.72 7.15 0.54 6.44e-11 Dupuytren's disease; TGCT cis rs9677476 0.863 rs58383275 chr2:232063946 T/C cg07929768 chr2:232055508 NA 0.31 4.49 0.37 1.61e-5 Food antigen IgG levels; TGCT cis rs7954584 0.567 rs11043243 chr12:122356370 G/C cg22168489 chr12:122356033 WDR66 0.22 4.79 0.4 4.59e-6 Mean corpuscular volume; TGCT cis rs9467773 0.869 rs1796520 chr6:26410800 C/T cg05738196 chr6:26577821 NA -0.62 -6.65 -0.51 8.38e-10 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs969049 chr4:98988857 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.568 rs5751159 chr22:42175365 G/A cg13695892 chr22:41940480 POLR3H 0.8 7.65 0.57 4.87e-12 Vitiligo; TGCT cis rs1372520 0.684 rs2583978 chr4:90750326 A/C cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs9399137 0.507 rs4451150 chr6:135279063 T/G cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg06640241 chr16:89574553 SPG7 0.64 6.12 0.48 1.12e-8 Multiple myeloma (IgH translocation); TGCT cis rs6570726 0.791 rs7755253 chr6:145858893 C/G cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6920965 0.561 rs9401851 chr6:126181956 T/C cg05901451 chr6:126070800 HEY2 -0.6 -6.29 -0.49 4.97e-9 High light scatter reticulocyte count; TGCT cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg01206211 chr2:36825736 FEZ2 0.33 5.56 0.45 1.59e-7 Height; TGCT cis rs3820928 1.000 rs59904960 chr2:227761269 T/C cg11843606 chr2:227700838 RHBDD1 -0.51 -4.49 -0.37 1.59e-5 Pulmonary function; TGCT cis rs4862750 0.914 rs11943333 chr4:187872455 A/G cg10295955 chr4:187884368 NA -0.92 -11.9 -0.73 3.04e-22 Lobe attachment (rater-scored or self-reported); TGCT cis rs8077577 0.945 rs11653988 chr17:18088833 C/T cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs13082711 0.595 rs1445114 chr3:27345489 C/A cg02860705 chr3:27208620 NA 0.48 7.57 0.56 7.46e-12 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs62103177 0.713 rs3744886 chr18:77659561 G/T cg12964065 chr18:77638022 KCNG2 0.37 4.75 0.39 5.6e-6 Opioid sensitivity; TGCT cis rs2970818 0.731 rs11063170 chr12:4575084 A/T cg02722637 chr12:4922070 KCNA6 0.33 4.64 0.38 8.73e-6 Phosphorus levels; TGCT cis rs3902035 0.929 rs62423968 chr6:119010514 T/C cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs765787 0.530 rs28524974 chr15:45543528 C/T cg24006582 chr15:45444508 DUOX1 -0.24 -5.29 -0.43 5.34e-7 Uric acid levels; TGCT cis rs7726839 0.561 rs72703044 chr5:579737 G/A cg09021430 chr5:549028 NA -0.37 -5.39 -0.44 3.37e-7 Obesity-related traits; TGCT cis rs2506155 0.752 rs2273466 chr10:33511047 A/G cg25928881 chr10:32632685 EPC1 0.33 5.03 0.41 1.66e-6 Migraine; TGCT cis rs1519814 0.654 rs1401810 chr8:121015820 C/T cg22335954 chr8:121166405 COL14A1 -0.38 -4.84 -0.4 3.81e-6 Breast cancer; TGCT cis rs597539 0.616 rs513476 chr11:68698996 C/T cg04772025 chr11:68637568 NA 0.6 6.75 0.52 5.08e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs739401 0.588 rs10219272 chr11:3020789 G/A cg25174290 chr11:3078921 CARS 0.48 4.57 0.38 1.17e-5 Longevity; TGCT cis rs739496 0.579 rs7310605 chr12:112292470 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7582180 0.681 rs6754176 chr2:100995691 C/T cg08017756 chr2:100939284 LONRF2 -0.31 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT trans rs1496653 0.602 rs71322172 chr3:23400571 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs6089829 0.962 rs4997812 chr20:61663153 T/G cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg07061783 chr6:25882402 NA -0.84 -8.67 -0.61 1.99e-14 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg03303774 chr4:1407052 NA 0.31 4.96 0.41 2.25e-6 Obesity-related traits; TGCT cis rs6952808 0.595 rs3800917 chr7:2167939 A/G cg04267008 chr7:1944627 MAD1L1 0.37 4.98 0.41 2.08e-6 Bipolar disorder and schizophrenia; TGCT cis rs644799 1.000 rs525404 chr11:95566520 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.01 0.58 7.27e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11719291 0.833 rs34037363 chr3:48821036 C/T cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 Cognitive function; TGCT cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg13695892 chr22:41940480 POLR3H 0.82 7.69 0.57 3.99e-12 Vitiligo; TGCT cis rs9300255 0.596 rs1568427 chr12:123738678 A/G cg00376283 chr12:123451042 ABCB9 0.78 6.62 0.51 9.59e-10 Neutrophil percentage of white cells; TGCT cis rs6570726 0.599 rs455001 chr6:145854450 A/T cg05347473 chr6:146136440 FBXO30 0.61 5.68 0.45 9.16e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg23758822 chr17:41437982 NA 0.72 6.77 0.52 4.51e-10 Menopause (age at onset); TGCT cis rs4273100 0.688 rs1467028 chr17:19174874 T/C cg03910582 chr17:19030146 GRAPL 0.49 5.88 0.47 3.58e-8 Schizophrenia; TGCT cis rs10431058 0.708 rs532859 chr11:107479652 G/A cg18204760 chr11:107461044 ELMOD1;LOC643923 0.57 4.83 0.4 3.9e-6 Common traits (Other); TGCT cis rs11190604 1.000 rs2489045 chr10:102344754 C/T cg16342193 chr10:102329863 NA -0.42 -5.26 -0.43 5.99e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.830 rs13137859 chr4:99050319 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4253772 0.591 rs9615343 chr22:46690824 C/G cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs1205863 1.000 rs1205883 chr6:11947911 C/T cg07106625 chr6:11870215 NA -0.51 -5.05 -0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs9291683 0.609 rs3796836 chr4:10011345 A/G cg00071950 chr4:10020882 SLC2A9 0.71 9.57 0.65 1.38e-16 Bone mineral density; TGCT cis rs2657888 1.000 rs2657888 chr12:56938383 A/C cg23002907 chr12:56915593 RBMS2 0.37 5.11 0.42 1.21e-6 Adiponectin levels; TGCT cis rs8180040 0.654 rs9837343 chr3:47177388 C/T cg27129171 chr3:47204927 SETD2 0.72 8.89 0.62 5.94e-15 Colorectal cancer; TGCT cis rs35160687 0.862 rs12476706 chr2:86528370 C/T cg03171300 chr2:86307199 POLR1A 0.32 5.44 0.44 2.73e-7 Night sleep phenotypes; TGCT cis rs11711311 0.911 rs34337798 chr3:113396704 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.82 -7.4 -0.55 1.82e-11 IgG glycosylation; TGCT cis rs2235642 0.691 rs2281235 chr16:1603535 T/C cg00463982 chr16:1583984 IFT140;TMEM204 -0.29 -5.06 -0.41 1.46e-6 Coronary artery disease; TGCT cis rs6570726 0.935 rs380433 chr6:145859601 A/T cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs17718580 0.609 rs59767247 chr14:51044774 C/A cg04730355 chr14:51134070 SAV1 1.25 8.77 0.62 1.16e-14 Cognitive performance; TGCT cis rs2153535 0.580 rs9379213 chr6:8474945 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs8013055 0.796 rs8005568 chr14:105971794 A/G cg23974065 chr14:106235526 NA 0.33 4.44 0.37 1.98e-5 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg07424592 chr7:64974309 NA -0.57 -5.55 -0.45 1.65e-7 Calcium levels; TGCT cis rs11031096 0.711 rs10835719 chr11:4203906 A/G cg18678763 chr11:4115507 RRM1 0.43 5.33 0.43 4.46e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1577917 1.000 rs12663690 chr6:86640162 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.64 5.22 0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs3743162 0.553 rs12900463 chr15:85415386 T/C cg11189052 chr15:85197271 WDR73 0.65 4.78 0.39 4.97e-6 Alzheimer's disease (age of onset); TGCT cis rs1903068 0.853 rs9312656 chr4:56002972 C/G cg09978860 chr4:56023921 NA 0.56 6.34 0.49 3.88e-9 Endometriosis; TGCT cis rs10883723 0.773 rs7917402 chr10:104246690 C/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9291683 0.588 rs17246745 chr4:9994583 T/C cg00071950 chr4:10020882 SLC2A9 0.72 9.19 0.64 1.13e-15 Bone mineral density; TGCT cis rs478304 0.627 rs11604568 chr11:65511336 G/A cg27068330 chr11:65405492 SIPA1 -0.93 -9.34 -0.64 4.92e-16 Acne (severe); TGCT cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.505 rs416968 chr1:53183513 A/G cg25767906 chr1:53392781 SCP2 -0.45 -5.17 -0.42 9.14e-7 Monocyte count; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg25767906 chr1:53392781 SCP2 -0.59 -6.92 -0.53 2.12e-10 Monocyte count; TGCT cis rs1903068 0.925 rs1551643 chr4:55994226 T/A cg01777861 chr4:56023843 NA 0.56 6.43 0.5 2.54e-9 Endometriosis; TGCT trans rs1814175 0.817 rs7947286 chr11:49874657 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs6671200 0.920 rs35403759 chr1:95702890 C/T cg20701556 chr1:95698924 RWDD3 0.67 5.63 0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs7027203 0.828 rs3996239 chr9:96611290 T/A cg13679303 chr9:96623674 NA -0.66 -10.76 -0.69 1.84e-19 DNA methylation (variation); TGCT cis rs981844 0.712 rs10014763 chr4:154739140 C/T cg14289246 chr4:154710475 SFRP2 0.96 8.92 0.63 4.99e-15 Response to statins (LDL cholesterol change); TGCT cis rs4788570 0.647 rs904764 chr16:71772795 G/A cg06353428 chr16:71660113 MARVELD3 1.54 12.41 0.74 1.74e-23 Intelligence (multi-trait analysis); TGCT cis rs10435719 0.610 rs76311455 chr8:11790526 C/G cg02840367 chr8:11660030 FDFT1 -0.54 -4.52 -0.38 1.45e-5 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs611744 0.529 rs13282825 chr8:109263237 T/C cg21045802 chr8:109455806 TTC35 0.7 7.05 0.54 1.07e-10 Dupuytren's disease; TGCT cis rs10779751 0.770 rs11121696 chr1:11238063 A/G cg08854313 chr1:11322531 MTOR -0.84 -6.81 -0.52 3.82e-10 Body mass index; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs12681287 0.547 rs7459877 chr8:87505660 G/A cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs9807989 0.811 rs7608638 chr2:102970289 A/G cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs8031584 0.678 rs798125 chr15:31116800 C/T cg14829155 chr15:31115871 NA 0.37 4.93 0.4 2.59e-6 Huntington's disease progression; TGCT cis rs2836974 0.897 rs8128102 chr21:40606414 G/A cg11890956 chr21:40555474 PSMG1 1.1 12.31 0.74 2.99e-23 Cognitive function; TGCT cis rs2013441 1.000 rs9904928 chr17:20180536 C/T cg18979559 chr17:20280153 CCDC144C 0.45 4.57 0.38 1.16e-5 Obesity-related traits; TGCT cis rs933688 1.000 rs1035476 chr5:90745976 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.01 8.6 0.61 2.93e-14 Smoking behavior; TGCT cis rs9921222 0.564 rs9923059 chr16:381590 C/A cg10349874 chr16:420996 TMEM8A;MRPL28 -0.26 -4.64 -0.38 8.86e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs72945132 0.882 rs3781648 chr11:70190058 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs28595532 0.925 rs116785973 chr4:119611350 G/A cg21605333 chr4:119757512 SEC24D 1.33 8.02 0.58 6.93e-13 Cannabis dependence symptom count; TGCT cis rs9436747 0.641 rs3790425 chr1:66043112 C/T cg14976592 chr1:65886160 LEPROT;LEPR -0.52 -4.65 -0.39 8.37e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg22920501 chr2:26401640 FAM59B -0.79 -6.35 -0.5 3.68e-9 Gut microbiome composition (summer); TGCT cis rs7017914 0.811 rs4272413 chr8:71636187 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT trans rs7618501 0.633 rs7628058 chr3:50039474 C/T cg21659725 chr3:3221576 CRBN 0.75 9.34 0.64 5.1e-16 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs7617773 0.784 rs9850672 chr3:48301172 C/A cg11946769 chr3:48343235 NME6 0.72 6.19 0.49 8.21e-9 Coronary artery disease; TGCT cis rs2836950 0.772 rs62222988 chr21:40569508 T/C cg11890956 chr21:40555474 PSMG1 -0.65 -6.2 -0.49 7.55e-9 Menarche (age at onset); TGCT cis rs7582180 0.700 rs11685401 chr2:100976685 A/G cg08017756 chr2:100939284 LONRF2 -0.31 -5.12 -0.42 1.12e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.816 rs405822 chr20:25501314 A/G cg16686733 chr20:25566563 NINL 0.52 5.05 0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.580 rs5758449 chr22:42140160 C/T cg03806693 chr22:41940476 POLR3H 0.93 9.08 0.63 2.06e-15 Vitiligo; TGCT cis rs9309473 0.606 rs62149777 chr2:73795364 G/A cg07208825 chr2:73871855 ALMS1P 0.25 4.79 0.4 4.66e-6 Metabolite levels; TGCT cis rs36051895 0.695 rs2183137 chr9:5026293 A/G cg02405213 chr9:5042618 JAK2 -0.78 -10.46 -0.68 9.47e-19 Pediatric autoimmune diseases; TGCT cis rs11690935 1.000 rs11678984 chr2:172535848 T/G cg13550731 chr2:172543902 DYNC1I2 1.2 12.8 0.75 2.01e-24 Schizophrenia; TGCT cis rs877529 0.625 rs139416 chr22:39554749 A/G cg18708252 chr22:39545030 CBX7 -0.38 -5.33 -0.43 4.41e-7 Multiple myeloma; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg25703541 chr22:24373054 LOC391322 -0.8 -8.28 -0.6 1.68e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6089829 0.962 rs6122344 chr20:61661738 C/T cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7216064 1.000 rs11869819 chr17:65868669 A/C cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7267979 1.000 rs2259926 chr20:25281733 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2762353 0.538 rs35670731 chr6:25728235 C/T cg03264133 chr6:25882463 NA 0.86 8.88 0.62 6.24e-15 Blood metabolite levels; TGCT cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.793 rs12402415 chr1:53218539 G/T cg16325326 chr1:53192061 ZYG11B -0.72 -8.82 -0.62 8.8e-15 Monocyte count; TGCT cis rs7666738 0.791 rs2081622 chr4:98927369 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2456568 0.900 rs2456559 chr11:93668858 A/T cg17595323 chr11:93583763 C11orf90 -0.46 -5.79 -0.46 5.39e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9811920 0.965 rs9289981 chr3:99868104 A/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.4 -4.44 -0.37 1.98e-5 Axial length; TGCT cis rs739496 0.527 rs7300320 chr12:112360168 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9473924 0.505 rs28360639 chr6:50783501 G/A cg14470998 chr6:50812995 TFAP2B 1.33 7.94 0.58 1.03e-12 Body mass index; TGCT cis rs79387448 0.701 rs76943877 chr2:102970677 T/C cg09003973 chr2:102972529 NA 1.47 10.36 0.68 1.69e-18 Gut microbiota (bacterial taxa); TGCT cis rs4273100 0.688 rs28760541 chr17:19172505 A/G cg01534423 chr17:18965556 NA 0.79 7.13 0.54 7.34e-11 Schizophrenia; TGCT cis rs8017423 0.967 rs4904662 chr14:90729427 G/A cg04374321 chr14:90722782 PSMC1 0.79 7.89 0.58 1.34e-12 Mortality in heart failure; TGCT cis rs7953249 0.542 rs2244608 chr12:121416988 A/G cg02403541 chr12:121454288 C12orf43 0.65 5.59 0.45 1.36e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs4478858 0.746 rs7544003 chr1:31689088 C/T cg00250761 chr1:31883323 NA 0.29 4.78 0.39 4.9e-6 Alcohol dependence; TGCT cis rs9467773 1.000 rs12526680 chr6:26550954 A/G cg26531700 chr6:26746687 NA 0.48 4.69 0.39 7.1e-6 Intelligence (multi-trait analysis); TGCT cis rs7961581 0.748 rs1798078 chr12:71595123 A/T cg07420333 chr12:71899429 LGR5 0.35 5.06 0.41 1.47e-6 Type 2 diabetes; TGCT cis rs8177253 0.965 rs7638018 chr3:133495461 C/T cg08439880 chr3:133502540 NA 0.31 6.05 0.48 1.56e-8 Iron status biomarkers; TGCT cis rs7223966 1.000 rs73337598 chr17:61732576 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 4.74 0.39 5.8e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs208520 0.909 rs9354410 chr6:67018584 C/T cg07460842 chr6:66804631 NA 0.73 5.91 0.47 3.07e-8 Exhaled nitric oxide output; TGCT cis rs13326165 0.715 rs11705963 chr3:52371991 T/G cg07884673 chr3:53033167 SFMBT1 0.4 4.86 0.4 3.45e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1784581 0.894 rs1790001 chr6:162387504 G/T cg17173639 chr6:162384350 PARK2 -0.5 -9.35 -0.64 4.63e-16 Itch intensity from mosquito bite; TGCT cis rs910187 0.605 rs6066223 chr20:45803998 A/G cg27589058 chr20:45804311 EYA2 0.37 8.25 0.6 1.96e-13 Migraine; TGCT cis rs7833790 0.685 rs13255262 chr8:82728024 T/G cg06027949 chr8:82754900 SNX16 -0.65 -5.03 -0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs1865760 1.000 rs6905887 chr6:25912103 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs263156 0.967 rs263119 chr6:142892729 A/G cg18419694 chr6:143832440 FUCA2 -0.39 -4.58 -0.38 1.1e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs2204008 0.748 rs8186658 chr12:38301461 A/C cg26384229 chr12:38710491 ALG10B 0.76 6.92 0.53 2.16e-10 Bladder cancer; TGCT cis rs2688608 0.592 rs3933085 chr10:75483331 C/T cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs1059312 0.932 rs4760589 chr12:129284382 T/C cg09035930 chr12:129282057 SLC15A4 0.59 11.59 0.72 1.72e-21 Systemic lupus erythematosus; TGCT cis rs1218582 0.772 rs12095061 chr1:154912968 A/T cg03351412 chr1:154909251 PMVK 0.52 4.92 0.4 2.66e-6 Prostate cancer; TGCT cis rs1062177 1.000 rs2347596 chr5:151179199 T/C cg00977110 chr5:151150581 G3BP1 0.39 4.51 0.38 1.49e-5 Preschool internalizing problems; TGCT cis rs4478037 0.558 rs72854770 chr3:33066743 C/G cg19404215 chr3:33155277 CRTAP 0.95 4.81 0.4 4.27e-6 Major depressive disorder; TGCT cis rs4727027 0.727 rs3801980 chr7:148878620 T/A cg15662616 chr7:148823355 ZNF425;ZNF398 0.56 4.6 0.38 1.03e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9660180 0.967 rs61422524 chr1:1767565 C/A cg17747265 chr1:1875780 NA -0.41 -7.55 -0.56 8.27e-12 Body mass index; TGCT cis rs751984 0.925 rs10897165 chr11:61277885 G/A cg17652291 chr11:60500967 NA -0.41 -4.58 -0.38 1.1e-5 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs651907 0.535 rs11717638 chr3:101505468 A/G cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs7618915 0.570 rs13068293 chr3:52672167 C/A cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs8017423 0.935 rs7160304 chr14:90752908 G/T cg04374321 chr14:90722782 PSMC1 0.76 7.46 0.56 1.33e-11 Mortality in heart failure; TGCT cis rs1153858 1.000 rs4775907 chr15:45638647 G/A cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs11098499 0.863 rs11933966 chr4:120476715 G/A cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs6570726 0.935 rs366621 chr6:145861275 A/G cg23711669 chr6:146136114 FBXO30 0.7 6.78 0.52 4.35e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2013441 1.000 rs1992562 chr17:20218793 A/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.59 -0.38 1.06e-5 Obesity-related traits; TGCT cis rs769267 0.965 rs2965191 chr19:19453521 T/G cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs7647973 0.577 rs6446247 chr3:49102001 A/T cg05785598 chr3:49045655 WDR6 0.39 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs826838 1.000 rs7953227 chr12:38946193 G/A cg13010199 chr12:38710504 ALG10B 0.78 6.76 0.52 4.7e-10 Heart rate; TGCT cis rs617219 0.698 rs7706045 chr5:78507910 T/G cg23987322 chr5:78407566 BHMT 0.38 5.07 0.41 1.39e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT trans rs17685 0.753 rs4573217 chr7:75733946 G/A cg19862616 chr7:65841803 NCRNA00174 0.49 7.91 0.58 1.24e-12 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1371867 0.846 rs1660329 chr8:101304048 G/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs10193935 0.901 rs7601905 chr2:42494144 A/G cg27598129 chr2:42591480 NA -0.34 -4.78 -0.39 4.92e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg07167872 chr1:205819463 PM20D1 0.57 7.07 0.54 9.84e-11 Menarche (age at onset); TGCT cis rs9357506 0.935 rs4714925 chr6:46304194 A/G cg21115430 chr6:46460003 NA -0.26 -5.13 -0.42 1.06e-6 Body mass index; TGCT cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg18654377 chr3:49208889 KLHDC8B -0.38 -5.02 -0.41 1.75e-6 Menarche (age at onset); TGCT cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg02579736 chr3:10068473 FANCD2;CIDECP -0.84 -5.44 -0.44 2.71e-7 Alzheimer's disease; TGCT cis rs17376456 0.597 rs7733142 chr5:93322795 C/A cg21475434 chr5:93447410 FAM172A -0.64 -5.95 -0.47 2.6e-8 Diabetic retinopathy; TGCT cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.817 rs10839465 chr11:49981554 C/A cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs9831754 0.756 rs12714468 chr3:78445878 A/T cg06138941 chr3:78371609 NA -0.4 -4.49 -0.37 1.61e-5 Calcium levels; TGCT cis rs4478858 0.698 rs11802155 chr1:31805012 T/C cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs1669338 0.507 rs4685606 chr3:3177973 T/G cg16797762 chr3:3221439 CRBN -0.88 -5.56 -0.45 1.58e-7 White matter integrity; TGCT cis rs9300255 0.602 rs1727314 chr12:123640664 C/A cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs10858047 0.883 rs12037358 chr1:115089279 T/C cg12756093 chr1:115239321 AMPD1 0.45 4.63 0.38 9.24e-6 Autism; TGCT cis rs7666738 0.830 rs2865989 chr4:99067532 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13082711 0.513 rs7612102 chr3:27372826 A/G cg02860705 chr3:27208620 NA -0.36 -5.39 -0.44 3.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs4455778 0.579 rs6969891 chr7:49123598 T/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.83e-9 Lung cancer in never smokers; TGCT cis rs192253604 1 rs192253604 chr16:68757769 G/A cg04413148 chr16:67965867 CTRL 0.57 4.71 0.39 6.59e-6 Asymmetrical dimethylarginine levels; TGCT cis rs7833790 0.724 rs6473310 chr8:82707981 A/G cg06027949 chr8:82754900 SNX16 -0.67 -5.24 -0.43 6.58e-7 Diastolic blood pressure; TGCT cis rs12681287 0.752 rs10092651 chr8:87247678 A/C cg27223183 chr8:87520930 FAM82B -0.81 -5.77 -0.46 5.91e-8 Caudate activity during reward; TGCT cis rs12530845 0.943 rs11984203 chr7:135325947 C/T cg23117316 chr7:135346802 PL-5283 0.5 4.74 0.39 5.83e-6 Red blood cell traits; TGCT cis rs12971120 1.000 rs2278162 chr18:72175814 A/G cg26446133 chr18:72167187 CNDP2 -0.33 -6.03 -0.48 1.74e-8 Refractive error; TGCT cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg11890956 chr21:40555474 PSMG1 -0.76 -7.08 -0.54 9.53e-11 Cognitive function; TGCT cis rs10876993 0.890 rs774887 chr12:58034835 A/G cg15848620 chr12:58087721 OS9 -0.71 -5.81 -0.46 4.86e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs56235845 0.694 rs11949401 chr5:176765989 A/G cg17509989 chr5:176798049 RGS14 0.55 7.58 0.56 6.89e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs9372498 0.908 rs72967581 chr6:118699329 G/A cg21191810 chr6:118973309 C6orf204 -0.5 -4.61 -0.38 9.92e-6 Diastolic blood pressure; TGCT cis rs9790314 0.905 rs6789388 chr3:160970437 G/A cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs6089829 0.851 rs6122346 chr20:61661822 C/G cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs17376456 1.000 rs59472588 chr5:93511981 A/G cg25358565 chr5:93447407 FAM172A 0.94 7.98 0.58 8.22e-13 Diabetic retinopathy; TGCT cis rs28595532 0.920 rs55633605 chr4:119761589 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT trans rs34421088 0.560 rs1478898 chr8:11395079 G/A cg15556689 chr8:8085844 FLJ10661 -0.77 -7.3 -0.55 3.07e-11 Neuroticism; TGCT cis rs4332037 0.539 rs55773130 chr7:2070554 T/C cg25834613 chr7:1915315 MAD1L1 -0.52 -5.11 -0.42 1.2e-6 Bipolar disorder; TGCT cis rs6683383 1.000 rs3766568 chr1:203101029 A/G cg04395153 chr1:203052423 MYOG 0.29 4.65 0.39 8.22e-6 Asthma; TGCT cis rs6088580 0.634 rs7271970 chr20:32987666 A/G cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs2201728 0.967 rs4147532 chr4:100211786 T/C cg07219303 chr4:100140905 ADH6 -0.35 -5.15 -0.42 9.78e-7 Cardiac Troponin-T levels; TGCT cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg00786635 chr1:25594202 NA 0.59 6.21 0.49 7.29e-9 Erythrocyte sedimentation rate; TGCT cis rs7647973 0.626 rs11130217 chr3:49737323 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs10791323 0.628 rs1893850 chr11:133705356 T/C cg03690763 chr11:133734501 NA -0.35 -5.44 -0.44 2.78e-7 Childhood ear infection; TGCT cis rs9868809 0.772 rs9811318 chr3:48702606 A/G cg00383909 chr3:49044727 WDR6 0.9 5.42 0.44 3.05e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs2354432 0.505 rs7551766 chr1:146858964 A/G cg25205988 chr1:146714368 CHD1L -1.34 -5.79 -0.46 5.52e-8 Mitochondrial DNA levels; TGCT cis rs72781680 0.898 rs72786298 chr2:24083011 C/T cg08917208 chr2:24149416 ATAD2B 0.9 5.5 0.44 2.06e-7 Lymphocyte counts; TGCT cis rs9527 0.590 rs7910900 chr10:104829898 C/T cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT cis rs7113874 0.589 rs6578968 chr11:8480719 G/T cg14521421 chr11:8862019 ST5 0.29 4.44 0.37 2e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg25703541 chr22:24373054 LOC391322 0.81 6.9 0.53 2.34e-10 S-phenylmercapturic acid levels in smokers; TGCT cis rs2172802 0.659 rs28713421 chr4:62497085 C/T cg04118610 chr4:62707027 LPHN3 0.42 4.5 0.37 1.55e-5 Partial epilepsies; TGCT cis rs6088580 0.634 rs6088488 chr20:32992631 T/C cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT trans rs7726839 0.561 rs72703058 chr5:584519 G/A cg11887960 chr12:57824829 NA 0.98 7.81 0.57 2.09e-12 Obesity-related traits; TGCT cis rs8077577 0.945 rs11655731 chr17:18107525 G/T cg09161412 chr17:18057145 MYO15A -0.64 -5.2 -0.42 7.92e-7 Obesity-related traits; TGCT cis rs7819412 0.775 rs34094119 chr8:10935898 A/G cg21775007 chr8:11205619 TDH -0.5 -4.61 -0.38 9.74e-6 Triglycerides; TGCT cis rs11648796 0.757 rs66649828 chr16:766078 A/G cg27144592 chr16:783916 NARFL 0.36 5.06 0.41 1.46e-6 Height; TGCT cis rs9486715 0.838 rs9400034 chr6:96954566 C/T cg18709589 chr6:96969512 KIAA0776 0.81 7.96 0.58 9.28e-13 Headache; TGCT cis rs2243480 1.000 rs316318 chr7:65612904 A/G cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs7208859 0.623 rs3752020 chr17:29111125 T/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7635838 0.503 rs9853547 chr3:11396101 C/G cg00170343 chr3:11313890 ATG7 0.64 6.15 0.48 9.73e-9 HDL cholesterol; TGCT cis rs7659604 0.676 rs7691955 chr4:122700462 A/T cg19748678 chr4:122722346 EXOSC9 0.86 9.13 0.63 1.63e-15 Type 2 diabetes; TGCT cis rs8013055 0.846 rs8013827 chr14:105970176 C/T cg23356831 chr14:105996513 TMEM121 -0.35 -5.63 -0.45 1.16e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs3885907 0.542 rs4147062 chr13:31320249 A/G cg22282089 chr13:30686841 NA 0.22 4.49 0.37 1.58e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT cis rs9611565 0.512 rs4512 chr22:42206084 G/C cg03806693 chr22:41940476 POLR3H -1.04 -10.57 -0.69 5.2e-19 Vitiligo; TGCT cis rs950776 0.616 rs647041 chr15:78880481 T/C cg06917634 chr15:78832804 PSMA4 -0.65 -5.3 -0.43 5.01e-7 Sudden cardiac arrest; TGCT trans rs10504390 0.656 rs80033165 chr8:66478523 T/A cg26037026 chr7:1641922 NA -0.64 -6.83 -0.52 3.39e-10 IgG glycosylation; TGCT cis rs568617 0.859 rs1204650 chr11:65645580 A/C cg04055107 chr11:65626734 MUS81;CFL1 -0.57 -5.22 -0.42 7.39e-7 Crohn's disease; TGCT cis rs916888 0.779 rs199498 chr17:44865603 A/G cg17911788 chr17:44343683 NA -0.51 -5.43 -0.44 2.81e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6952808 0.792 rs4721184 chr7:1950784 T/C cg04267008 chr7:1944627 MAD1L1 -0.39 -5.18 -0.42 8.84e-7 Bipolar disorder and schizophrenia; TGCT cis rs7811142 0.943 rs66958101 chr7:100074020 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs56309584 0.673 rs11651993 chr17:8115774 A/G cg08322244 chr17:8066669 VAMP2 -0.55 -5.47 -0.44 2.4e-7 Initial pursuit acceleration; TGCT cis rs2735413 0.564 rs74715500 chr16:78095412 A/C cg09132178 chr16:78079569 NA 0.33 4.44 0.37 1.98e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg08219700 chr8:58056026 NA 0.37 4.48 0.37 1.71e-5 Developmental language disorder (linguistic errors); TGCT cis rs9393692 1.000 rs9393692 chr6:26276650 A/G cg05868516 chr6:26286170 HIST1H4H 0.62 5.86 0.47 3.96e-8 Educational attainment; TGCT cis rs4862750 0.914 rs11945845 chr4:187874136 T/C cg10295955 chr4:187884368 NA -0.96 -13.44 -0.77 5.81e-26 Lobe attachment (rater-scored or self-reported); TGCT cis rs10927875 1.000 rs12138117 chr1:16305279 T/C cg21385522 chr1:16154831 NA -0.76 -8.29 -0.6 1.6e-13 Dilated cardiomyopathy; TGCT cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg00684032 chr4:1343700 KIAA1530 0.23 5.02 0.41 1.73e-6 Obesity-related traits; TGCT cis rs7772486 0.590 rs1890170 chr6:146071839 G/C cg13319975 chr6:146136371 FBXO30 0.73 6.55 0.51 1.36e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT trans rs13064411 0.542 rs13082603 chr3:113223362 T/C cg00307254 chr3:126706825 PLXNA1 0.34 6.78 0.52 4.36e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs137603 0.623 rs137657 chr22:39733242 G/T cg17798944 chr22:39715225 SNORD43;RPL3 -0.64 -6.96 -0.53 1.77e-10 Primary biliary cholangitis; TGCT cis rs951366 0.870 rs3747973 chr1:205677148 A/G cg07157834 chr1:205819609 PM20D1 0.35 4.99 0.41 2.03e-6 Menarche (age at onset); TGCT cis rs6598955 0.724 rs7547520 chr1:26592310 C/T cg04990556 chr1:26633338 UBXN11 -0.91 -11.45 -0.72 3.65e-21 Obesity-related traits; TGCT cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs933688 1.000 rs2367526 chr5:90740525 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.49 0.61 5.31e-14 Smoking behavior; TGCT cis rs7666738 0.791 rs12233867 chr4:98950233 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1395 0.961 rs4665965 chr2:27536380 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.49 -6.39 -0.5 3.02e-9 Blood metabolite levels; TGCT cis rs35160687 0.901 rs12714180 chr2:86525323 G/T cg12542933 chr2:85804724 VAMP8 0.4 4.81 0.4 4.21e-6 Night sleep phenotypes; TGCT cis rs76878669 0.917 rs10896110 chr11:66101978 G/A cg18002602 chr11:66138449 SLC29A2 -0.51 -5.71 -0.46 7.78e-8 Educational attainment (years of education); TGCT cis rs5769765 0.908 rs138891 chr22:50227741 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.36 5.48 0.44 2.25e-7 Schizophrenia; TGCT cis rs1008375 1.000 rs2058338 chr4:17678600 A/G cg18681998 chr4:17616180 MED28 -0.99 -12.02 -0.73 1.52e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1814175 0.817 rs10769613 chr11:49769692 G/A cg11707556 chr5:10655725 ANKRD33B -0.38 -7.76 -0.57 2.75e-12 Height; TGCT cis rs9467773 0.526 rs9348710 chr6:26360486 A/C cg05738196 chr6:26577821 NA -0.63 -6.8 -0.52 3.97e-10 Intelligence (multi-trait analysis); TGCT cis rs832540 0.898 rs331498 chr5:56249842 C/G cg12311346 chr5:56204834 C5orf35 0.46 4.88 0.4 3.15e-6 Coronary artery disease; TGCT cis rs11120822 0.787 rs11120829 chr1:7123793 A/C cg20434152 chr1:7120926 CAMTA1 -0.29 -4.58 -0.38 1.11e-5 Stearic acid (18:0) levels; TGCT cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs4285028 0.948 rs34181646 chr3:121705373 T/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs13020137 1 rs13020137 chr2:130757304 A/G cg03206401 chr2:130956119 TUBA3E -0.53 -4.81 -0.4 4.26e-6 Schizophrenia; TGCT cis rs12142240 0.698 rs45449893 chr1:46859024 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs6121246 0.908 rs6089094 chr20:30431771 C/T cg18721089 chr20:30220636 NA -0.45 -4.98 -0.41 2.12e-6 Mean corpuscular hemoglobin; TGCT cis rs79349575 0.783 rs62075852 chr17:47017176 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs7586879 0.789 rs13398155 chr2:25128550 C/T cg01884057 chr2:25150051 NA 0.27 4.72 0.39 6.29e-6 Body mass index; TGCT cis rs10501293 0.746 rs7952412 chr11:43017772 C/T cg03447554 chr11:43094025 NA 0.44 6.32 0.49 4.2e-9 Cognitive performance; TGCT cis rs6570726 0.791 rs7755253 chr6:145858893 C/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs904251 0.580 rs62408367 chr6:37444813 G/A cg08126542 chr6:37504118 NA -0.39 -5.37 -0.43 3.75e-7 Cognitive performance; TGCT cis rs9913156 0.748 rs55959711 chr17:4562581 C/A cg00122941 chr17:4613640 ARRB2 0.87 7.38 0.55 1.95e-11 Lymphocyte counts; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg22166914 chr1:53195759 ZYG11B -0.42 -7.38 -0.55 2.01e-11 Monocyte count; TGCT cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs2249625 0.508 rs114505309 chr6:72892383 G/A cg08500200 chr6:72892038 RIMS1 0.43 4.62 0.38 9.5e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs11585357 0.501 rs17458091 chr1:17595925 A/G cg08277548 chr1:17600880 PADI3 -0.72 -5.19 -0.42 8.2e-7 Hair shape; TGCT cis rs736408 0.812 rs9324 chr3:52825585 T/C cg10802521 chr3:52805072 NEK4 -0.7 -8.15 -0.59 3.38e-13 Bipolar disorder; TGCT cis rs28595532 0.920 rs56046676 chr4:119766733 A/G cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs7829975 0.509 rs2945269 chr8:8115578 G/C cg08975724 chr8:8085496 FLJ10661 0.63 6.01 0.47 1.93e-8 Mood instability; TGCT cis rs11030122 0.702 rs10835406 chr11:3992954 G/T cg18678763 chr11:4115507 RRM1 0.5 6.19 0.49 7.92e-9 Mean platelet volume;Platelet distribution width; TGCT cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.24e-9 Blood metabolite levels; TGCT cis rs2370759 1.000 rs11597888 chr10:32635834 G/A cg01819863 chr10:32635814 EPC1 1.0 9.52 0.65 1.8e-16 Sexual dysfunction (female); TGCT cis rs11264213 0.901 rs72661632 chr1:36420715 G/A cg27506609 chr1:36549197 TEKT2 0.41 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs7822232 0.908 rs4977164 chr8:145144912 T/G cg14631276 chr8:145163102 KIAA1875 -0.56 -5.05 -0.41 1.55e-6 Blood metabolite levels; TGCT cis rs12497850 0.931 rs9835307 chr3:48857805 T/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs3806843 0.576 rs246034 chr5:140332064 A/C cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs4642101 0.824 rs9852222 chr3:12848491 G/T cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs7662987 0.517 rs1311617 chr4:100012425 T/G cg12011299 chr4:100065546 ADH4 0.4 4.76 0.39 5.33e-6 Smoking initiation; TGCT cis rs10782582 0.593 rs12142247 chr1:76235746 C/T cg03433033 chr1:76189801 ACADM -0.55 -6.05 -0.48 1.61e-8 Daytime sleep phenotypes; TGCT cis rs7216064 0.589 rs7213585 chr17:66062316 A/T cg12091567 chr17:66097778 LOC651250 -1.09 -9.43 -0.65 2.99e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7833790 0.750 rs10108955 chr8:82690644 C/T cg27398817 chr8:82754497 SNX16 -0.83 -5.96 -0.47 2.43e-8 Diastolic blood pressure; TGCT cis rs7666738 0.830 rs7686456 chr4:99019695 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 1.000 rs1867778 chr2:233679644 C/T cg08000102 chr2:233561755 GIGYF2 -0.64 -6.51 -0.5 1.71e-9 Coronary artery disease; TGCT cis rs259282 0.605 rs34727912 chr19:33110058 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.54 4.91 0.4 2.76e-6 Schizophrenia; TGCT cis rs2463822 0.547 rs72917373 chr11:62024403 C/A cg06239285 chr11:62104954 ASRGL1 -0.96 -6.14 -0.48 1.01e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT trans rs7618501 0.633 rs12496973 chr3:50002245 T/C cg21659725 chr3:3221576 CRBN 0.75 9.11 0.63 1.79e-15 Intelligence (multi-trait analysis); TGCT cis rs9527 0.567 rs11191573 chr10:104896816 T/C cg15744005 chr10:104629667 AS3MT -0.43 -4.94 -0.41 2.45e-6 Arsenic metabolism; TGCT cis rs2204008 0.744 rs11181635 chr12:38378420 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.3 0.55 2.97e-11 Bladder cancer; TGCT cis rs7666738 0.791 rs1426674 chr4:98924247 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1215050 0.791 rs592053 chr4:98732220 C/T cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 1.95e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11217036 1 rs11217036 chr11:118675772 C/T cg19308663 chr11:118741387 NA 0.31 6.43 0.5 2.56e-9 Allergy; TGCT cis rs7017914 0.837 rs2732105 chr8:71923645 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.2e-6 Bone mineral density; TGCT cis rs3749237 0.964 rs1799845 chr3:49847623 A/G cg10152585 chr3:50297680 NA 0.48 4.58 0.38 1.14e-5 Resting heart rate; TGCT cis rs2070488 0.965 rs9877282 chr3:38541452 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.86 -9.01 -0.63 3.14e-15 Electrocardiographic conduction measures; TGCT cis rs1865760 0.964 rs9295677 chr6:25933712 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.05 0.48 1.59e-8 Height; TGCT cis rs9467711 0.651 rs9467623 chr6:25860580 G/A cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10779751 0.770 rs12075896 chr1:11200350 C/A cg08854313 chr1:11322531 MTOR -0.82 -6.66 -0.51 7.99e-10 Body mass index; TGCT cis rs1801251 1.000 rs283475 chr2:233654381 A/C cg25237894 chr2:233734115 C2orf82 -0.28 -5.01 -0.41 1.81e-6 Coronary artery disease; TGCT cis rs2798269 0.604 rs6490662 chr13:22153280 A/G cg18095732 chr13:22033692 ZDHHC20 -0.5 -4.43 -0.37 2.01e-5 PR segment; TGCT cis rs11098499 0.818 rs10008791 chr4:120431469 A/C cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.28e-9 Corneal astigmatism; TGCT cis rs9659323 1.000 rs6680737 chr1:119521631 G/A cg07961512 chr1:119535619 NA 0.44 5.07 0.41 1.4e-6 Body mass index; TGCT cis rs2153535 0.526 rs7748404 chr6:8472500 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs17268829 0.927 rs10253362 chr7:94077302 G/T cg06439941 chr7:93550756 GNG11 -0.24 -4.49 -0.37 1.61e-5 Breast cancer; TGCT cis rs3845702 0.668 rs6759271 chr2:180844303 T/C cg01881094 chr2:180872142 CWC22 -1.08 -7.0 -0.53 1.39e-10 Schizophrenia; TGCT cis rs4819052 0.851 rs4819043 chr21:46660078 G/A cg06618935 chr21:46677482 NA -0.36 -5.71 -0.46 7.76e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28595532 0.841 rs114966236 chr4:119733437 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs2730245 0.636 rs710421 chr7:158668575 T/C cg11984989 chr7:158649758 WDR60 1.08 10.47 0.68 9.26e-19 Height; TGCT cis rs916888 0.738 rs199515 chr17:44856641 C/G cg17911788 chr17:44343683 NA 0.57 5.82 0.46 4.65e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4975709 0.610 rs1531994 chr5:1859297 T/C cg07747251 chr5:1868357 NA 0.38 5.28 0.43 5.55e-7 Cardiovascular disease risk factors; TGCT cis rs7246657 0.722 rs10410588 chr19:38042410 C/G cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs10493773 0.775 rs12738010 chr1:86102575 A/C cg17807903 chr1:86174739 ZNHIT6 0.45 6.36 0.5 3.47e-9 Urate levels in overweight individuals; TGCT cis rs916888 0.610 rs199442 chr17:44820122 G/A cg01570182 chr17:44337453 NA 0.83 8.02 0.58 6.61e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs72913475 0.579 rs112094677 chr18:44180253 T/C cg09157302 chr4:25656830 SLC34A2 0.65 6.7 0.52 6.55e-10 Midgestational circulating levels of PBDEs (fetal genetic effect); TGCT cis rs7914558 0.901 rs35525740 chr10:104941112 A/T cg05855489 chr10:104503620 C10orf26 0.5 4.47 0.37 1.71e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs80264589 1 rs80264589 chr6:26927602 G/A cg12315302 chr6:26189340 HIST1H4D 0.93 4.48 0.37 1.71e-5 Lung cancer;Intelligence (multi-trait analysis); TGCT cis rs7072216 0.763 rs2274245 chr10:100175082 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs7666738 0.791 rs10856933 chr4:98958542 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs739401 0.572 rs384490 chr11:3078885 A/C cg25174290 chr11:3078921 CARS 0.49 4.77 0.39 5.17e-6 Longevity; TGCT cis rs806215 0.723 rs1090682 chr7:127245159 T/C cg25922125 chr7:127225783 GCC1 0.59 5.98 0.47 2.17e-8 Type 2 diabetes; TGCT cis rs9467773 1.000 rs9357010 chr6:26527945 C/G cg05738196 chr6:26577821 NA 0.88 12.9 0.76 1.15e-24 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg10150615 chr22:24372951 LOC391322 1.01 13.23 0.77 1.86e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7172971 0.655 rs11070357 chr15:42340142 G/T cg05886115 chr15:42349113 NA 0.32 4.92 0.4 2.71e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT trans rs3780486 0.874 rs10813955 chr9:33141791 C/T cg20290983 chr6:43655470 MRPS18A 1.18 14.66 0.8 7.66e-29 IgG glycosylation; TGCT cis rs4074961 0.505 rs4653306 chr1:38065390 C/T cg17933807 chr1:38061675 GNL2 1.09 16.57 0.83 3.19e-33 Axial length; TGCT cis rs7147624 0.766 rs11158597 chr14:65913536 T/G cg03016385 chr14:66212404 NA -0.5 -7.18 -0.54 5.64e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg17554472 chr22:41940697 POLR3H -0.44 -4.8 -0.4 4.39e-6 Vitiligo; TGCT cis rs6922617 0.685 rs73419209 chr6:41346584 T/A cg07798131 chr6:41471673 NA 0.98 4.85 0.4 3.6e-6 Alzheimer's disease biomarkers; TGCT cis rs6882046 0.513 rs446219 chr5:88005827 T/C cg24804195 chr5:87968844 LOC645323 -0.61 -6.15 -0.48 9.97e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs6089829 0.962 rs1116450 chr20:61658210 T/C cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs11085466 1.000 rs75211977 chr19:21760201 G/A cg02997983 chr19:21646781 NA -0.64 -4.52 -0.38 1.43e-5 Colorectal or endometrial cancer; TGCT cis rs2180341 0.924 rs6930849 chr6:127630963 A/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs7677751 0.767 rs890204 chr4:55064439 C/G cg17187183 chr4:55093834 PDGFRA 0.47 6.19 0.49 8.05e-9 Corneal astigmatism; TGCT cis rs926938 0.618 rs1286560 chr1:115375930 C/T cg12756093 chr1:115239321 AMPD1 -0.41 -6.02 -0.48 1.84e-8 Autism; TGCT cis rs12477438 0.501 rs7608938 chr2:99782226 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs2243480 1.000 rs58669269 chr7:65951953 T/C cg18252515 chr7:66147081 NA -1.18 -7.56 -0.56 7.99e-12 Diabetic kidney disease; TGCT cis rs2228479 0.867 rs17784386 chr16:89947457 A/G cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs2120019 0.938 rs2304903 chr15:75315778 A/G cg11632617 chr15:75315747 PPCDC -0.3 -4.44 -0.37 1.95e-5 Blood trace element (Zn levels); TGCT cis rs9399135 0.967 rs9376075 chr6:135296963 A/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs1372520 0.684 rs3113355 chr4:90745345 A/T cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.11e-7 Neuroticism; TGCT cis rs11690935 0.688 rs7600835 chr2:172521827 C/T cg13550731 chr2:172543902 DYNC1I2 -0.91 -7.83 -0.58 1.87e-12 Schizophrenia; TGCT cis rs7267979 1.000 rs2500404 chr20:25359758 A/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.05 0.41 1.54e-6 Prudent dietary pattern; TGCT cis rs13108904 0.870 rs4974543 chr4:1251222 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.63 0.38 8.9e-6 Obesity-related traits; TGCT cis rs9993613 0.875 rs58977516 chr4:73452414 A/T cg15102770 chr4:73434591 ADAMTS3 0.52 4.71 0.39 6.4e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs2013441 1.000 rs17759923 chr17:20022035 G/A cg23224458 chr17:20280056 CCDC144C 0.4 4.72 0.39 6.33e-6 Obesity-related traits; TGCT cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs2370759 1.000 rs11599522 chr10:32568434 G/C cg01819863 chr10:32635814 EPC1 1.03 9.87 0.66 2.63e-17 Sexual dysfunction (female); TGCT cis rs1552244 0.515 rs67342818 chr3:10166406 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs4523957 0.553 rs2476355 chr17:2029559 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2439831 0.850 rs3097773 chr15:43893072 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.83 -5.7 -0.46 8.12e-8 Lung cancer in ever smokers; TGCT cis rs6754311 0.773 rs4988183 chr2:136622046 T/C cg07169764 chr2:136633963 MCM6 0.76 6.97 0.53 1.7e-10 Mosquito bite size; TGCT cis rs7178572 0.524 rs12914128 chr15:77493875 T/C cg22256960 chr15:77711686 NA -0.88 -8.99 -0.63 3.53e-15 Type 2 diabetes; TGCT cis rs7267979 0.932 rs13040655 chr20:25582197 C/T cg16686733 chr20:25566563 NINL 0.56 5.43 0.44 2.81e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7192750 0.586 rs3794692 chr16:71961339 T/C cg06353428 chr16:71660113 MARVELD3 0.81 7.15 0.54 6.72e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2439831 0.850 rs28684672 chr15:44107662 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.27 0.49 5.48e-9 Lung cancer in ever smokers; TGCT cis rs2354432 0.714 rs7531962 chr1:146746023 G/A cg25205988 chr1:146714368 CHD1L -1.25 -7.96 -0.58 9.46e-13 Mitochondrial DNA levels; TGCT cis rs1461503 0.900 rs10892935 chr11:122838590 C/T cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs2070433 0.752 rs2839220 chr21:47774330 G/C cg12379764 chr21:47803548 PCNT 0.64 5.37 0.43 3.68e-7 Lymphocyte counts; TGCT cis rs7659604 0.628 rs3828485 chr4:122722368 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.31 -0.43 4.83e-7 Type 2 diabetes; TGCT cis rs7208859 0.673 rs2269916 chr17:29233763 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.830 rs13125432 chr4:98961253 G/A cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs6854902 chr4:99033416 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.720 rs4896844 chr6:146075224 T/C cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT trans rs1908814 0.516 rs7812563 chr8:11794488 T/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs9467711 0.606 rs9379873 chr6:26402717 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.68 -0.39 7.4e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs4332037 0.539 rs62444881 chr7:2052318 C/T cg25206134 chr2:45395956 NA 1.0 7.55 0.56 8.15e-12 Bipolar disorder; TGCT cis rs7267979 0.586 rs6037057 chr20:25182089 T/C cg14121845 chr20:25566513 NINL 0.45 4.88 0.4 3.23e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4654899 1.000 rs6684976 chr1:21367501 G/A cg01072550 chr1:21505969 NA -0.49 -7.87 -0.58 1.47e-12 Superior frontal gyrus grey matter volume; TGCT cis rs4555082 0.834 rs2816652 chr14:105712493 C/T cg01266790 chr14:105781312 PACS2 0.55 4.49 0.37 1.58e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs4654899 0.606 rs651085 chr1:21097783 A/G cg01072550 chr1:21505969 NA 0.53 8.91 0.62 5.45e-15 Superior frontal gyrus grey matter volume; TGCT cis rs7412746 0.588 rs10305664 chr1:150839686 A/C cg04414720 chr1:150670196 GOLPH3L 0.39 4.75 0.39 5.55e-6 Melanoma; TGCT cis rs7647973 1.000 rs2177268 chr3:49439725 A/T cg07636037 chr3:49044803 WDR6 -0.72 -5.79 -0.46 5.35e-8 Menarche (age at onset); TGCT cis rs4731207 0.596 rs12540261 chr7:124586837 A/G cg10503827 chr7:124401702 GPR37 -0.2 -4.63 -0.38 9.26e-6 Cutaneous malignant melanoma; TGCT cis rs6912958 0.781 rs7757636 chr6:88256092 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs7590720 0.959 rs2372684 chr2:216884764 C/A cg12620499 chr2:216877984 MREG 0.88 9.65 0.66 8.69e-17 Alcohol dependence; TGCT cis rs1949733 1.000 rs1880023 chr4:8480831 C/T cg13073564 chr4:8508604 NA 0.49 5.17 0.42 8.98e-7 Response to antineoplastic agents; TGCT cis rs13256369 1.000 rs4841017 chr8:8577093 A/G cg06671706 chr8:8559999 CLDN23 0.35 4.69 0.39 6.95e-6 Obesity-related traits; TGCT cis rs9296092 0.538 rs9469491 chr6:33521545 A/G cg13560919 chr6:33536144 NA 0.2 4.59 0.38 1.07e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs11190604 1.000 rs11190595 chr10:102291761 T/C cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1799949 0.628 rs4474733 chr17:41433660 G/T cg10047753 chr17:41438598 NA 0.8 6.77 0.52 4.47e-10 Menopause (age at onset); TGCT trans rs7618501 1.000 rs11709680 chr3:49745188 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT trans rs17818859 0.661 rs6743063 chr2:134652361 T/C cg15779785 chr12:2521414 CACNA1C 0.62 6.94 0.53 1.92e-10 Neurofibrillary tangles; TGCT cis rs1670533 1.000 rs2045069 chr4:1052206 T/C cg27284194 chr4:1044797 NA 0.7 5.88 0.47 3.62e-8 Recombination rate (females); TGCT cis rs7666738 0.611 rs34982650 chr4:98819530 T/A cg17366294 chr4:99064904 C4orf37 0.7 7.45 0.56 1.42e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.774 rs11495721 chr12:38337224 A/C cg26384229 chr12:38710491 ALG10B 0.78 6.87 0.53 2.71e-10 Bladder cancer; TGCT cis rs7845219 0.506 rs12548999 chr8:95929843 C/T cg13393036 chr8:95962371 TP53INP1 -0.43 -5.02 -0.41 1.76e-6 Type 2 diabetes; TGCT cis rs8070740 0.579 rs28429022 chr17:5354471 A/G cg25236894 chr17:5323110 RPAIN;NUP88 0.53 4.72 0.39 6.2e-6 Menopause (age at onset); TGCT cis rs910316 0.935 rs2268620 chr14:75640403 G/A cg23033748 chr14:75592666 NEK9 -0.29 -4.88 -0.4 3.17e-6 Height; TGCT cis rs4478858 0.681 rs12136293 chr1:31703650 A/G cg00250761 chr1:31883323 NA -0.28 -4.68 -0.39 7.5e-6 Alcohol dependence; TGCT cis rs514406 0.644 rs4926928 chr1:53210163 G/T cg16325326 chr1:53192061 ZYG11B 0.86 12.54 0.75 8.24e-24 Monocyte count; TGCT cis rs10992471 0.603 rs11788523 chr9:95256593 G/A cg14631576 chr9:95140430 CENPP -0.31 -4.61 -0.38 9.95e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4727027 0.782 rs10245343 chr7:148796333 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.6 5.4 0.44 3.33e-7 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9926296 0.656 rs11861084 chr16:89875710 G/T cg26513180 chr16:89883248 FANCA -0.73 -6.89 -0.53 2.53e-10 Vitiligo; TGCT cis rs4727027 0.866 rs2373437 chr7:148779032 T/C cg23583168 chr7:148888333 NA -0.69 -8.67 -0.61 2.04e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs875971 0.830 rs778715 chr7:65849209 C/T cg11764359 chr7:65958608 NA 0.57 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs35306767 0.953 rs11253521 chr10:976416 G/C cg18964960 chr10:1102726 WDR37 0.57 4.67 0.39 7.63e-6 Eosinophil percentage of granulocytes; TGCT cis rs3784262 1.000 rs4646586 chr15:58305344 C/A cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.82 -0.57 1.98e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9993613 0.875 rs1518485 chr4:73470972 C/T cg15102770 chr4:73434591 ADAMTS3 -0.53 -4.79 -0.4 4.62e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs3820928 0.935 rs113195824 chr2:227769139 A/G cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 6.12e-6 Pulmonary function; TGCT cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12497850 0.866 rs6791234 chr3:48996137 A/G cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.94e-6 Parkinson's disease; TGCT cis rs11741688 0.631 rs4444956 chr5:178325515 A/G cg09339527 chr5:178322752 ZFP2 -0.32 -5.06 -0.41 1.45e-6 Sleep duration; TGCT cis rs4902562 1.000 rs4902562 chr14:68731458 C/T cg18825221 chr14:68749962 RAD51L1 0.24 5.0 0.41 1.88e-6 Systemic lupus erythematosus; TGCT cis rs4242434 0.747 rs6986550 chr8:22467870 T/A cg03733263 chr8:22462867 KIAA1967 1.08 17.08 0.84 2.22e-34 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9611565 0.525 rs9611549 chr22:41705909 C/G cg03806693 chr22:41940476 POLR3H -0.81 -7.85 -0.58 1.69e-12 Vitiligo; TGCT cis rs763014 0.932 rs2384975 chr16:651115 G/T cg07343612 chr16:622815 PIGQ -0.41 -8.15 -0.59 3.29e-13 Height; TGCT cis rs10193935 1.000 rs12612527 chr2:42392099 T/C cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs568617 0.716 rs111953392 chr11:65595697 G/A cg04055107 chr11:65626734 MUS81;CFL1 0.67 5.34 0.43 4.34e-7 Crohn's disease; TGCT cis rs72945132 0.579 rs35077099 chr11:70247970 G/A cg00319359 chr11:70116639 PPFIA1 0.92 7.0 0.53 1.4e-10 Coronary artery disease; TGCT cis rs4722166 0.695 rs7808122 chr7:22798080 A/G cg26061582 chr7:22766209 IL6 0.49 6.45 0.5 2.31e-9 Lung cancer; TGCT cis rs9653442 0.564 rs2309753 chr2:100775920 C/A cg22139774 chr2:100720529 AFF3 -0.34 -5.4 -0.44 3.21e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7824557 0.527 rs2572449 chr8:11239137 A/G cg21775007 chr8:11205619 TDH 0.72 6.96 0.53 1.79e-10 Retinal vascular caliber; TGCT cis rs7940866 0.774 rs12420126 chr11:130834811 C/T cg05962950 chr11:130786565 SNX19 0.74 7.1 0.54 8.74e-11 Schizophrenia; TGCT cis rs7772486 0.875 rs932522 chr6:146374026 A/G cg13319975 chr6:146136371 FBXO30 0.51 4.6 0.38 1.02e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.644 rs4926928 chr1:53210163 G/T cg24675658 chr1:53192096 ZYG11B -0.82 -10.33 -0.68 1.99e-18 Monocyte count; TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg02493798 chr17:6899577 ALOX12 0.43 4.99 0.41 2.03e-6 Tonsillectomy; TGCT trans rs57221529 0.713 rs12521091 chr5:590710 G/T cg11887960 chr12:57824829 NA 1.25 10.0 0.67 1.29e-17 Lung disease severity in cystic fibrosis; TGCT cis rs7666738 0.830 rs10028692 chr4:98962585 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8072100 0.738 rs9895509 chr17:45549618 A/T cg08085267 chr17:45401833 C17orf57 0.52 5.81 0.46 5e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4555082 0.718 rs75139030 chr14:105710853 A/AG cg01266790 chr14:105781312 PACS2 0.55 4.49 0.37 1.58e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs2013441 0.760 rs8080827 chr17:20173936 G/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.55 -0.38 1.25e-5 Obesity-related traits; TGCT cis rs909002 0.849 rs2280386 chr1:32086912 A/C cg11573219 chr1:32083031 HCRTR1 -0.49 -6.45 -0.5 2.26e-9 Intelligence (multi-trait analysis); TGCT cis rs17001868 0.568 rs3788578 chr22:40742921 C/T cg07138101 chr22:40742427 ADSL 0.72 5.25 0.43 6.46e-7 Mammographic density (dense area); TGCT cis rs9868809 0.505 rs28793701 chr3:48762683 C/G cg00383909 chr3:49044727 WDR6 1.25 6.74 0.52 5.38e-10 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs858239 0.932 rs858275 chr7:23294144 T/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.12 -0.42 1.16e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7582180 0.614 rs1030901 chr2:101007314 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.77 -0.39 5.16e-6 Intelligence (multi-trait analysis); TGCT cis rs908922 0.676 rs1337338 chr1:152511885 G/A cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs634534 0.622 rs1192168 chr11:65730945 T/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.54 5.18 0.42 8.63e-7 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs72945132 1.000 rs72945129 chr11:70110808 C/T cg00319359 chr11:70116639 PPFIA1 0.96 6.82 0.52 3.47e-10 Coronary artery disease; TGCT cis rs35306767 0.714 rs7072554 chr10:1090988 C/T cg20503657 chr10:835505 NA 0.47 5.25 0.43 6.4e-7 Eosinophil percentage of granulocytes; TGCT cis rs968451 0.865 rs5757610 chr22:39707979 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.83 8.1 0.59 4.48e-13 Primary biliary cholangitis; TGCT cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg12311346 chr5:56204834 C5orf35 -0.66 -6.63 -0.51 9.22e-10 Initial pursuit acceleration; TGCT cis rs9796 0.558 rs4445868 chr15:41531991 C/T cg18705301 chr15:41695430 NDUFAF1 -0.54 -6.9 -0.53 2.43e-10 Menopause (age at onset); TGCT cis rs36051895 0.632 rs11790841 chr9:5166273 G/C cg02405213 chr9:5042618 JAK2 -0.7 -8.84 -0.62 7.69e-15 Pediatric autoimmune diseases; TGCT trans rs2727020 0.729 rs1164666 chr11:49295867 C/T cg15704280 chr7:45808275 SEPT13 -0.71 -8.04 -0.59 6.04e-13 Coronary artery disease; TGCT cis rs6678914 0.966 rs12032080 chr1:202196697 C/T cg08883485 chr1:201619787 NAV1 -0.4 -4.71 -0.39 6.45e-6 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs801193 1.000 rs2707845 chr7:66198798 C/T cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.97e-7 Aortic root size; TGCT cis rs346785 0.640 rs11077809 chr17:74284854 A/C cg09812376 chr17:74270190 QRICH2 -0.37 -5.6 -0.45 1.31e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs13188771 0.690 rs350543 chr5:100864959 C/T cg10455971 chr5:101119566 NA 0.43 4.53 0.38 1.38e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs6500602 0.727 rs11076836 chr16:4569331 G/A cg08645402 chr16:4508243 NA 0.19 5.3 0.43 5.14e-7 Schizophrenia; TGCT cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg06481639 chr22:41940642 POLR3H -0.66 -5.75 -0.46 6.46e-8 Vitiligo; TGCT cis rs10193935 0.901 rs222471 chr2:42638057 C/T cg27598129 chr2:42591480 NA 0.38 5.45 0.44 2.57e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs62380364 0.870 rs4373304 chr5:88152202 T/C cg22951263 chr5:87985283 NA -0.46 -4.53 -0.38 1.38e-5 Intelligence (multi-trait analysis); TGCT trans rs66573146 0.901 rs55882710 chr4:7030704 G/A cg07817883 chr1:32538562 TMEM39B 1.69 8.54 0.61 4.08e-14 Granulocyte percentage of myeloid white cells; TGCT cis rs9611565 0.512 rs5996063 chr22:42168767 G/A cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs6951245 0.554 rs10270249 chr7:1151886 G/T cg18402987 chr7:1209562 NA 0.47 4.69 0.39 7.03e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs13082711 1.000 rs35944308 chr3:27536356 G/A cg02860705 chr3:27208620 NA 0.34 4.64 0.38 8.68e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7584330 0.657 rs7599658 chr2:238352898 A/C cg14458575 chr2:238380390 NA -0.52 -7.61 -0.56 5.91e-12 Prostate cancer; TGCT cis rs7914558 0.933 rs1538204 chr10:104733893 T/A cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.34e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs939658 0.683 rs11634726 chr15:79465894 A/G cg17916960 chr15:79447300 NA -0.43 -6.82 -0.52 3.48e-10 Refractive error; TGCT cis rs11874712 0.931 rs35507656 chr18:43652541 A/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.11 0.42 1.19e-6 Migraine - clinic-based; TGCT cis rs2067615 0.599 rs3759310 chr12:107166122 C/G cg15890332 chr12:107067104 RFX4 0.28 5.55 0.45 1.66e-7 Heart rate; TGCT cis rs7829975 0.742 rs1533058 chr8:8685190 A/G cg08975724 chr8:8085496 FLJ10661 0.53 4.87 0.4 3.32e-6 Mood instability; TGCT cis rs2288073 0.965 rs10185445 chr2:24410976 A/C cg02683114 chr2:24398427 C2orf84 0.24 5.72 0.46 7.53e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg16405210 chr4:1374714 KIAA1530 -0.24 -4.44 -0.37 2e-5 Longevity; TGCT cis rs7017914 0.902 rs6472563 chr8:71969907 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.28 -0.43 5.57e-7 Bone mineral density; TGCT cis rs9394841 0.667 rs9471653 chr6:41755410 C/G cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs6460942 0.915 rs17541464 chr7:12462675 A/G cg06484146 chr7:12443880 VWDE -0.53 -5.59 -0.45 1.36e-7 Coronary artery disease; TGCT cis rs909674 0.514 rs7423 chr22:39781429 C/T cg11247378 chr22:39784982 NA -0.74 -10.58 -0.69 4.94e-19 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9357506 1.000 rs6910951 chr6:46307502 C/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs2836950 0.527 rs2836948 chr21:40599677 T/C cg11644478 chr21:40555479 PSMG1 -0.54 -5.1 -0.42 1.25e-6 Menarche (age at onset); TGCT cis rs3741404 0.609 rs687581 chr11:63871533 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.74 -7.48 -0.56 1.16e-11 Platelet count; TGCT cis rs3099143 1.000 rs3102712 chr15:77058926 G/A cg21673338 chr15:77095150 SCAPER -0.53 -5.22 -0.42 7.33e-7 Recalcitrant atopic dermatitis; TGCT cis rs7113874 0.589 rs10840060 chr11:8500045 A/C cg14521421 chr11:8862019 ST5 -0.29 -4.71 -0.39 6.47e-6 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs36051895 0.632 rs7032616 chr9:5180996 T/C cg02405213 chr9:5042618 JAK2 -0.74 -10.46 -0.68 9.7e-19 Pediatric autoimmune diseases; TGCT cis rs939658 0.967 rs7172074 chr15:79452726 T/C cg17916960 chr15:79447300 NA 0.53 8.37 0.6 1.04e-13 Refractive error; TGCT cis rs9926296 0.585 rs8045232 chr16:89857548 A/G cg03388025 chr16:89894329 SPIRE2 0.49 8.58 0.61 3.29e-14 Vitiligo; TGCT cis rs1799949 0.794 rs116409325 chr17:41445460 C/A cg05368731 chr17:41323189 NBR1 1.19 14.26 0.79 6.45e-28 Menopause (age at onset); TGCT cis rs12580194 0.556 rs73119000 chr12:55736662 G/A cg10672482 chr12:55725839 OR6C3 -0.51 -4.51 -0.38 1.46e-5 Cancer; TGCT cis rs12477438 1.000 rs12053372 chr2:99810055 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.74 -5.75 -0.46 6.59e-8 Chronic sinus infection; TGCT cis rs6951245 1.000 rs79327308 chr7:1108141 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs2708977 1.000 rs10184209 chr2:97337491 G/T cg01950434 chr2:97203154 ARID5A 0.62 5.68 0.45 9.28e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs11105298 0.891 rs4842654 chr12:89834428 T/A cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4285028 0.747 rs4048699 chr3:121404483 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.9 7.24 0.54 4.24e-11 Multiple sclerosis; TGCT cis rs6582630 0.519 rs11609739 chr12:38547969 G/A cg13010199 chr12:38710504 ALG10B 0.62 5.02 0.41 1.74e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs77741769 0.529 rs525425 chr12:121195625 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.52 0.38 1.42e-5 Mean corpuscular volume; TGCT cis rs1609391 0.543 rs1347209 chr3:136626697 G/T cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs12477438 0.520 rs6712704 chr2:99719687 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs1218582 0.774 rs4845679 chr1:154861187 G/T cg06221963 chr1:154839813 KCNN3 -0.8 -15.37 -0.81 1.66e-30 Prostate cancer; TGCT cis rs2797160 1.000 rs1418639 chr6:125999940 C/T cg05901451 chr6:126070800 HEY2 -0.74 -6.48 -0.5 1.96e-9 Endometrial cancer; TGCT trans rs6089829 0.962 rs6089826 chr20:61668595 G/A cg23505145 chr19:12996616 KLF1 0.89 9.9 0.66 2.21e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs1577917 1.000 rs1857965 chr6:86630776 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs9467773 1.000 rs9467773 chr6:26498426 A/G cg05738196 chr6:26577821 NA 0.87 12.41 0.74 1.7e-23 Intelligence (multi-trait analysis); TGCT cis rs2120019 1.000 rs2415255 chr15:75332412 A/G cg17294928 chr15:75287854 SCAMP5 -0.78 -6.12 -0.48 1.14e-8 Blood trace element (Zn levels); TGCT cis rs7043114 0.525 rs7026361 chr9:95138564 A/C cg13798575 chr9:95087839 CENPP;NOL8 0.54 5.45 0.44 2.61e-7 Height; TGCT cis rs7698623 0.850 rs2045834 chr4:88800642 C/T cg27387453 chr4:88533842 DSPP -0.6 -4.53 -0.38 1.35e-5 Cardiovascular disease risk factors; TGCT cis rs6089829 0.889 rs6062773 chr20:61663262 G/C cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7959452 0.640 rs4274230 chr12:69700772 T/G cg14784868 chr12:69753453 YEATS4 0.68 6.95 0.53 1.81e-10 Blood protein levels; TGCT cis rs1552244 0.766 rs34232505 chr3:10186216 T/A cg00149659 chr3:10157352 C3orf10 1.0 5.69 0.46 8.55e-8 Alzheimer's disease; TGCT cis rs8062405 0.540 rs151226 chr16:28549823 A/C cg09754948 chr16:28834200 ATXN2L 0.55 4.54 0.38 1.3e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs700651 0.789 rs892514 chr2:198905270 T/C cg00792783 chr2:198669748 PLCL1 0.59 5.09 0.42 1.28e-6 Intracranial aneurysm; TGCT cis rs6952808 0.691 rs2398709 chr7:2112548 C/T cg22963979 chr7:1858916 MAD1L1 -0.41 -6.25 -0.49 5.93e-9 Bipolar disorder and schizophrenia; TGCT cis rs2404602 0.647 rs118129828 chr15:77015200 T/C cg23625390 chr15:77176239 SCAPER -0.38 -4.82 -0.4 4.05e-6 Blood metabolite levels; TGCT cis rs9435341 0.762 rs2878349 chr1:107549245 G/A cg09367891 chr1:107599246 PRMT6 0.67 5.75 0.46 6.66e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs2204008 0.583 rs12307593 chr12:38317803 A/G cg26384229 chr12:38710491 ALG10B 0.53 4.68 0.39 7.52e-6 Bladder cancer; TGCT cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.41 -4.88 -0.4 3.13e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9394841 0.692 rs9394834 chr6:41806793 G/A cg08135965 chr6:41755394 TOMM6 0.54 4.96 0.41 2.31e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs2730260 0.537 rs3793223 chr7:158863574 C/A cg27122614 chr7:157913741 PTPRN2 0.43 4.45 0.37 1.87e-5 Myopia (pathological); TGCT cis rs9388451 0.807 rs1268070 chr6:126041164 A/G cg05901451 chr6:126070800 HEY2 -1.04 -12.92 -0.76 1.04e-24 Brugada syndrome; TGCT cis rs858239 0.601 rs73272048 chr7:23152653 C/G cg05602783 chr7:23145260 KLHL7 -0.66 -5.54 -0.45 1.75e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg06873352 chr17:61820015 STRADA 0.4 4.47 0.37 1.73e-5 Prudent dietary pattern; TGCT cis rs4786125 0.636 rs7187960 chr16:6919183 G/T cg03623568 chr16:6915990 A2BP1 -0.45 -6.77 -0.52 4.65e-10 Heart rate variability traits (SDNN); TGCT cis rs1538970 0.504 rs3790585 chr1:46023356 A/T cg05343316 chr1:45956843 TESK2 0.67 4.88 0.4 3.24e-6 Platelet count; TGCT cis rs17152411 0.895 rs61872117 chr10:126581842 A/G cg07906193 chr10:126599966 NA 0.43 4.68 0.39 7.47e-6 Height; TGCT trans rs12599106 0.679 rs34584967 chr16:34475725 T/G cg11235426 chr6:292522 DUSP22 -0.64 -6.75 -0.52 4.94e-10 Menopause (age at onset); TGCT cis rs7659604 0.582 rs3217780 chr4:122737278 T/C cg06713675 chr4:122721982 EXOSC9 -0.69 -9.7 -0.66 6.92e-17 Type 2 diabetes; TGCT cis rs2404602 0.716 rs17362383 chr15:76650702 A/G cg22467129 chr15:76604101 ETFA -0.56 -6.78 -0.52 4.34e-10 Blood metabolite levels; TGCT cis rs35306767 0.903 rs11253493 chr10:936931 T/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs6882046 0.513 rs625970 chr5:88042296 A/G cg24804195 chr5:87968844 LOC645323 -0.58 -5.72 -0.46 7.57e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2692947 0.726 rs13009727 chr2:96769883 C/G cg22654517 chr2:96458247 NA -0.21 -4.55 -0.38 1.26e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2153535 0.580 rs1119691 chr6:8460452 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs3026101 0.647 rs4790263 chr17:5307084 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.53 0.38 1.38e-5 Body mass index; TGCT cis rs6964587 1.000 rs7802788 chr7:91736874 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.21e-5 Breast cancer; TGCT cis rs910316 1.000 rs4322591 chr14:75600697 C/T cg23033748 chr14:75592666 NEK9 0.28 4.79 0.39 4.73e-6 Height; TGCT cis rs13102973 0.682 rs7441468 chr4:135886736 C/T cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs6570726 0.791 rs11155432 chr6:145898761 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4972806 0.814 rs4246626 chr2:177046430 A/C cg03152288 chr2:177042942 NA 0.52 4.51 0.38 1.5e-5 IgG glycosylation; TGCT cis rs904251 0.704 rs2776873 chr6:37483142 A/G cg08126542 chr6:37504118 NA -0.43 -5.31 -0.43 4.88e-7 Cognitive performance; TGCT trans rs57221529 0.766 rs72703070 chr5:590458 T/C cg25482853 chr8:67687455 SGK3 1.22 10.56 0.69 5.48e-19 Lung disease severity in cystic fibrosis; TGCT cis rs9560113 0.843 rs9555808 chr13:112181284 A/T cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs2832191 0.740 rs6516890 chr21:30476812 T/A cg24692254 chr21:30365293 RNF160 0.94 10.58 0.69 4.82e-19 Dental caries; TGCT cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg12310025 chr6:25882481 NA -0.53 -5.45 -0.44 2.63e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs62321570 chr4:98984276 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs13064411 0.501 rs13092925 chr3:113209375 C/G cg00307254 chr3:126706825 PLXNA1 0.34 6.72 0.52 5.79e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2762353 0.562 rs1165206 chr6:25867566 G/A cg03517284 chr6:25882590 NA -0.61 -6.15 -0.48 9.83e-9 Blood metabolite levels; TGCT cis rs7772486 0.754 rs2328709 chr6:146106819 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -4.83 -0.4 3.97e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6912958 0.781 rs2325064 chr6:88224467 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs1577917 0.958 rs7453105 chr6:86500761 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs254781 0.527 rs254778 chr5:88009593 A/G cg22951263 chr5:87985283 NA 0.56 4.84 0.4 3.75e-6 Intelligence (multi-trait analysis); TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg05457628 chr5:178986728 RUFY1 -0.54 -6.26 -0.49 5.7e-9 Lung cancer; TGCT cis rs6988636 1.000 rs28537152 chr8:124189071 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs67311347 1.000 rs7633809 chr3:40517737 A/G cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs10992471 0.639 rs10821008 chr9:95487497 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.73 -0.46 7.21e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9818758 0.607 rs4855860 chr3:49526044 A/T cg08550065 chr3:50336684 HYAL3;NAT6 -1.17 -4.98 -0.41 2.11e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1552244 0.882 rs17050660 chr3:10001772 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.91 -6.04 -0.48 1.67e-8 Alzheimer's disease; TGCT cis rs7552404 0.727 rs1159214 chr1:76317910 G/T cg10523679 chr1:76189770 ACADM -0.67 -6.36 -0.5 3.5e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6565180 0.888 rs13333093 chr16:30407269 C/A cg17640201 chr16:30407289 ZNF48 1.04 10.4 0.68 1.35e-18 Tonsillectomy; TGCT cis rs12681287 0.640 rs12679811 chr8:87465370 T/C cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs3771570 0.901 rs4675944 chr2:242430170 C/T cg21155796 chr2:242212141 HDLBP 0.89 6.82 0.52 3.55e-10 Prostate cancer; TGCT cis rs783147 1.000 rs783147 chr6:161137990 C/T cg09810169 chr6:161694730 AGPAT4 -0.49 -4.71 -0.39 6.49e-6 Lp (a) levels; TGCT cis rs6752107 0.967 rs6431661 chr2:234167421 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.88 0.4 3.17e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3096299 0.967 rs28644774 chr16:89472181 G/C cg02187348 chr16:89574699 SPG7 0.47 4.45 0.37 1.9e-5 Multiple myeloma (IgH translocation); TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg24503407 chr1:205819492 PM20D1 0.68 10.52 0.69 6.7e-19 Menarche (age at onset); TGCT cis rs4924935 1.000 rs1737947 chr17:18831432 A/G cg26378065 chr17:18585709 ZNF286B -0.58 -4.88 -0.4 3.2e-6 Pancreatic cancer; TGCT cis rs6088590 0.707 rs67159833 chr20:33488079 T/C cg06115741 chr20:33292138 TP53INP2 0.64 4.87 0.4 3.4e-6 Coronary artery disease; TGCT cis rs9638182 0.673 rs13221253 chr7:72922233 A/G cg14087351 chr7:73037990 MLXIPL -0.57 -4.52 -0.38 1.4e-5 Triglycerides; TGCT cis rs1215050 0.791 rs2123099 chr4:98803456 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs6998277 1.000 rs4734648 chr8:103635994 G/A cg10187029 chr8:103597600 NA 0.47 5.91 0.47 3.05e-8 Migraine; TGCT cis rs1401999 0.659 rs4912518 chr3:183752027 C/T cg20387954 chr3:183756860 HTR3D -0.22 -4.61 -0.38 9.8200000000000008e-06 Anterior chamber depth; TGCT cis rs1062177 1.000 rs2964571 chr5:151171256 C/T cg12924095 chr5:151150029 G3BP1 0.35 5.09 0.42 1.31e-6 Preschool internalizing problems; TGCT cis rs6500602 0.702 rs1051308 chr16:4560301 A/G cg08645402 chr16:4508243 NA -0.17 -4.78 -0.39 4.96e-6 Schizophrenia; TGCT cis rs2404602 1.000 rs12443137 chr15:76840832 G/T cg26408565 chr15:76604113 ETFA -0.41 -5.16 -0.42 9.55e-7 Blood metabolite levels; TGCT cis rs9611565 0.504 rs5758452 chr22:42144927 G/A cg06634786 chr22:41940651 POLR3H 0.78 7.31 0.55 2.85e-11 Vitiligo; TGCT cis rs11175492 0.528 rs12368329 chr12:65031566 A/T cg18624581 chr12:65153313 GNS -0.8 -4.57 -0.38 1.17e-5 Platelet count; TGCT cis rs10782582 0.609 rs5745553 chr1:76379135 A/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.55 4.74 0.39 5.73e-6 Daytime sleep phenotypes; TGCT cis rs6754311 0.593 rs10195620 chr2:136495619 A/T cg07169764 chr2:136633963 MCM6 -0.66 -6.12 -0.48 1.11e-8 Mosquito bite size; TGCT cis rs61990749 0.597 rs8003691 chr14:78211225 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs7772486 0.686 rs9390348 chr6:146044748 C/T cg23711669 chr6:146136114 FBXO30 -0.88 -9.77 -0.66 4.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs801193 1.000 rs7785213 chr7:66138978 A/C cg00343986 chr7:65444356 GUSB -0.22 -5.01 -0.41 1.84e-6 Aortic root size; TGCT cis rs2180341 1.000 rs6569479 chr6:127606588 A/G cg27446573 chr6:127587934 RNF146 1.07 9.46 0.65 2.57e-16 Breast cancer; TGCT cis rs35883536 0.626 rs10783140 chr1:101042083 A/G cg14855972 chr1:101004472 GPR88 -0.24 -4.49 -0.37 1.64e-5 Monocyte count; TGCT cis rs769267 0.930 rs2288852 chr19:19605348 T/C cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs2075371 0.966 rs2544225 chr7:133995838 A/C cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs1250248 0.526 rs724617 chr2:216282481 A/G cg16261737 chr2:216301490 FN1 0.5 4.51 0.38 1.47e-5 Total cholesterol levels; TGCT cis rs9291683 0.588 rs6844329 chr4:10018544 T/C cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Bone mineral density; TGCT cis rs2204008 0.811 rs4882300 chr12:38415224 A/T cg26384229 chr12:38710491 ALG10B -0.78 -6.97 -0.53 1.62e-10 Bladder cancer; TGCT cis rs2153535 0.580 rs1119691 chr6:8460452 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs12497850 0.931 rs4072859 chr3:49032205 G/C cg07636037 chr3:49044803 WDR6 0.96 10.59 0.69 4.61e-19 Parkinson's disease; TGCT cis rs11118844 0.696 rs11118860 chr1:221953558 A/G cg04222084 chr1:221915650 DUSP10 0.83 5.07 0.41 1.4e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs17767294 0.708 rs34144478 chr6:27834677 C/T cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs3996993 0.724 rs2749010 chr6:52626572 A/G cg20803780 chr6:52668592 GSTA1 0.33 4.44 0.37 1.97e-5 Hemoglobin concentration; TGCT cis rs8180040 0.805 rs17410853 chr3:47363971 G/T cg27129171 chr3:47204927 SETD2 -0.6 -6.52 -0.51 1.63e-9 Colorectal cancer; TGCT cis rs9419702 0.568 rs7075233 chr10:133545170 A/G cg04492858 chr10:133558786 NA -0.52 -5.65 -0.45 1.05e-7 Survival in rectal cancer; TGCT cis rs4555082 0.834 rs2735817 chr14:105717796 A/G cg01266790 chr14:105781312 PACS2 -0.56 -4.56 -0.38 1.21e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs4975709 0.610 rs4975706 chr5:1860365 G/T cg15595755 chr5:1867978 NA 0.46 5.31 0.43 4.79e-7 Cardiovascular disease risk factors; TGCT cis rs11997175 0.740 rs6991071 chr8:33814103 G/A ch.8.33884649F chr8:33765107 NA 0.34 5.28 0.43 5.56e-7 Body mass index; TGCT cis rs921968 0.613 rs556497 chr2:219446477 G/A cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs11690935 0.959 rs3770452 chr2:172668682 A/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.55 -0.75 7.86e-24 Schizophrenia; TGCT cis rs10493773 0.502 rs12061951 chr1:86081453 A/G cg17807903 chr1:86174739 ZNHIT6 -0.39 -4.77 -0.39 5.16e-6 Urate levels in overweight individuals; TGCT cis rs7208859 0.573 rs11656121 chr17:29214043 A/G cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28595532 0.920 rs56302493 chr4:119772382 A/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs4851266 0.898 rs10496346 chr2:100853267 A/G cg07810366 chr2:100720526 AFF3 0.34 4.85 0.4 3.65e-6 Educational attainment; TGCT cis rs9467711 0.659 rs34605993 chr6:26454363 C/T cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs17376456 0.877 rs28575883 chr5:93346035 T/C cg21475434 chr5:93447410 FAM172A 0.63 4.77 0.39 5.14e-6 Diabetic retinopathy; TGCT cis rs7824557 0.564 rs7839307 chr8:11198792 A/G cg21775007 chr8:11205619 TDH 0.74 6.99 0.53 1.49e-10 Retinal vascular caliber; TGCT cis rs7746199 0.668 rs34864796 chr6:27459923 G/A cg02458000 chr6:26745757 NA -0.94 -4.46 -0.37 1.82e-5 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs3020333 0.653 rs851982 chr6:152024985 T/C cg22157087 chr6:152012887 ESR1 0.25 5.99 0.47 2.13e-8 Total body bone mineral density; TGCT cis rs3125734 0.633 rs4979782 chr10:63998527 C/T cg19640130 chr10:64028056 RTKN2 -0.39 -5.04 -0.41 1.64e-6 Rheumatoid arthritis; TGCT cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg12310025 chr6:25882481 NA 0.52 4.62 0.38 9.65e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs1124253 chr4:98949682 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 0.786 rs77943789 chr7:1140158 C/T cg27454412 chr7:1067447 C7orf50 0.56 4.66 0.39 8e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10992471 0.580 rs10992304 chr9:95085365 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.59 -0.45 1.35e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1775715 0.707 rs1541262 chr10:32179771 A/G cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs826838 1.000 rs2129627 chr12:38653036 C/T cg26384229 chr12:38710491 ALG10B 1.05 10.25 0.68 3.18e-18 Heart rate; TGCT cis rs6700896 0.500 rs12040007 chr1:66080160 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7178572 0.633 rs12901130 chr15:77848806 C/T cg22256960 chr15:77711686 NA -0.82 -7.32 -0.55 2.69e-11 Type 2 diabetes; TGCT cis rs2120019 0.567 rs8025170 chr15:75170983 A/G cg09165964 chr15:75287851 SCAMP5 0.85 6.73 0.52 5.72e-10 Blood trace element (Zn levels); TGCT cis rs7830933 0.955 rs57220043 chr8:23602763 A/T cg04349084 chr8:23602677 NA 0.25 4.9 0.4 2.96e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT trans rs1908814 0.516 rs11250178 chr8:11800234 A/C cg15556689 chr8:8085844 FLJ10661 0.78 7.35 0.55 2.37e-11 Neuroticism; TGCT cis rs709400 1.000 rs3915733 chr14:104147353 G/A cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs12134133 0.719 rs6696142 chr1:207402243 C/T cg02152968 chr1:207494213 CD55 0.69 4.75 0.39 5.46e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs2228479 0.717 rs12917681 chr16:89810941 C/A cg27121462 chr16:89883253 FANCA 0.77 4.61 0.38 9.93e-6 Skin colour saturation; TGCT cis rs59197085 0.636 rs2307037 chr7:128449405 G/A cg00260937 chr7:128520193 KCP 0.47 4.9 0.4 2.92e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs1670533 0.932 rs13140341 chr4:1054235 T/C cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs12681287 0.647 rs2953510 chr8:87341914 T/C cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs1801251 1.000 rs6714245 chr2:233580505 T/C cg25237894 chr2:233734115 C2orf82 0.32 5.68 0.45 8.92e-8 Coronary artery disease; TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg24675658 chr1:53192096 ZYG11B -0.84 -10.27 -0.68 2.8e-18 Monocyte count; TGCT cis rs4953345 0.627 rs11900910 chr2:46557600 C/T cg12598524 chr2:46088325 PRKCE -0.24 -4.7 -0.39 6.69e-6 Renal cell carcinoma; TGCT cis rs10464366 0.746 rs12674262 chr7:39141728 G/T cg18850127 chr7:39170497 POU6F2 0.29 6.38 0.5 3.23e-9 IgG glycosylation; TGCT cis rs751984 0.852 rs11230728 chr11:61277698 A/G cg17652291 chr11:60500967 NA -0.41 -4.58 -0.38 1.1e-5 Diastolic blood pressure;Systolic blood pressure;Mean arterial pressure; TGCT cis rs1448094 0.544 rs56330110 chr12:86166666 A/G cg02569458 chr12:86230093 RASSF9 0.38 4.55 0.38 1.25e-5 Major depressive disorder; TGCT cis rs9467773 0.836 rs1977198 chr6:26466225 A/C cg15659132 chr6:26577336 NA 0.58 5.98 0.47 2.23e-8 Intelligence (multi-trait analysis); TGCT cis rs1524927 1.000 rs1524927 chr7:96371732 C/T cg03808172 chr7:96339361 SHFM1 -0.49 -5.34 -0.43 4.22e-7 Total body bone mineral density; TGCT cis rs2050392 0.557 rs306588 chr10:30723593 G/A cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs5769765 0.565 rs8137232 chr22:50256885 G/C cg22709217 chr22:50311962 ALG12;CRELD2 1.0 6.16 0.48 9.32e-9 Schizophrenia; TGCT cis rs7091068 0.518 rs4144098 chr10:95432600 C/T cg20715218 chr10:95462985 C10orf4 0.52 5.56 0.45 1.59e-7 Urinary tract infection frequency; TGCT cis rs13272623 0.502 rs268594 chr8:71513130 C/T cg23757474 chr8:71581111 LACTB2;XKR9 0.6 5.08 0.42 1.33e-6 IgG glycosylation; TGCT cis rs9522267 0.535 rs9515451 chr13:112234382 A/G cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs7772486 0.790 rs2253764 chr6:146199881 T/A cg05347473 chr6:146136440 FBXO30 0.52 4.88 0.4 3.15e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9517302 0.615 rs7983522 chr13:99098055 C/T cg22223119 chr13:99095684 FARP1 -0.51 -5.67 -0.45 9.51e-8 Obesity-related traits; TGCT cis rs2153535 0.580 rs9406171 chr6:8515362 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs11943027 0.818 rs7688418 chr4:38900057 C/G cg25943096 chr4:38869650 MIR574;FAM114A1 0.33 4.49 0.37 1.6e-5 Alcohol dependence; TGCT cis rs6088580 0.634 rs6142159 chr20:32993035 G/A cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs4824093 0.610 rs2208023 chr22:50249983 A/G cg14114931 chr22:50943910 LMF2 0.36 4.51 0.38 1.51e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6543140 0.964 rs6543143 chr2:103085420 A/C cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs2067615 0.560 rs10467028 chr12:107076405 A/G cg15890332 chr12:107067104 RFX4 0.3 5.87 0.47 3.69e-8 Heart rate; TGCT cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs797680 1.000 rs797680 chr1:93716974 G/T cg17826107 chr1:92977322 EVI5 0.24 5.18 0.42 8.56e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7607369 0.714 rs4674334 chr2:219622811 T/C cg02176678 chr2:219576539 TTLL4 -0.5 -6.48 -0.5 1.92e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs71435601 0.600 rs475887 chr2:21389485 T/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs1062177 0.774 rs2964574 chr5:151155711 G/A cg12924095 chr5:151150029 G3BP1 0.34 5.02 0.41 1.78e-6 Preschool internalizing problems; TGCT cis rs6558530 0.615 rs12674711 chr8:1699608 A/G cg09410841 chr8:1729607 CLN8 0.72 6.48 0.5 1.98e-9 Systolic blood pressure; TGCT cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.19e-5 Obesity-related traits; TGCT cis rs6840360 0.967 rs17027798 chr4:152597540 A/G cg17479576 chr4:152424074 FAM160A1 -0.49 -5.18 -0.42 8.55e-7 Intelligence (multi-trait analysis); TGCT cis rs6459804 0.566 rs76186270 chr7:157512420 C/T cg14168080 chr7:157504135 PTPRN2 -0.41 -4.85 -0.4 3.57e-6 Bipolar disorder and schizophrenia; TGCT cis rs3087591 0.708 rs10445402 chr17:29661340 G/T cg24425628 chr17:29625626 OMG;NF1 0.39 5.68 0.45 8.93e-8 Hip circumference; TGCT cis rs908922 0.676 rs10888491 chr1:152492622 A/G cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.16e-9 Hair morphology; TGCT cis rs1891275 0.515 rs7911755 chr10:93489817 G/A cg08448711 chr10:92794806 NA -0.34 -4.48 -0.37 1.69e-5 Intelligence (multi-trait analysis); TGCT cis rs4851266 1.000 rs13034176 chr2:100833913 G/A cg22139774 chr2:100720529 AFF3 -0.35 -5.41 -0.44 3.1e-7 Educational attainment; TGCT cis rs10927875 0.501 rs9660676 chr1:16279041 C/T cg21385522 chr1:16154831 NA -0.94 -9.6 -0.65 1.15e-16 Dilated cardiomyopathy; TGCT cis rs9467773 1.000 rs11756120 chr6:26529808 G/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9814567 1.000 rs7433663 chr3:134235790 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -8.81 -0.62 9.26e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7193541 0.662 rs8058133 chr16:74657485 A/T cg01733217 chr16:74700730 RFWD3 1.03 14.16 0.79 1.15e-27 Multiple myeloma; TGCT cis rs651907 0.535 rs13094911 chr3:101519021 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs6089584 0.853 rs1740367 chr20:60574834 C/T cg06108461 chr20:60628389 TAF4 -0.6 -8.5 -0.61 4.95e-14 Body mass index; TGCT cis rs17711722 0.523 rs313812 chr7:65505043 T/C cg07424592 chr7:64974309 NA 0.62 6.03 0.48 1.71e-8 Calcium levels; TGCT trans rs1814175 0.817 rs4881623 chr11:49804991 C/T cg03929089 chr4:120376271 NA -0.7 -8.19 -0.59 2.72e-13 Height; TGCT cis rs6546537 0.824 rs3771543 chr2:69784255 C/T cg10773587 chr2:69614142 GFPT1 -0.71 -6.88 -0.53 2.63e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs28595532 0.764 rs116788606 chr4:119748849 G/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT trans rs17685 0.712 rs60721456 chr7:75743820 T/A cg19862616 chr7:65841803 NCRNA00174 0.53 9.28 0.64 7.02e-16 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs858239 0.570 rs10235467 chr7:23148808 C/T cg05602783 chr7:23145260 KLHL7 -0.66 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs67311347 0.956 rs13066971 chr3:40462510 A/T cg13683864 chr3:40499215 RPL14 1.01 10.44 0.68 1.1e-18 Renal cell carcinoma; TGCT cis rs12935418 0.616 rs8047785 chr16:80969352 T/C cg07676361 chr16:80966860 NA -0.35 -4.69 -0.39 6.99e-6 Mean corpuscular volume; TGCT cis rs1008375 0.898 rs2079892 chr4:17577163 G/A cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg06634786 chr22:41940651 POLR3H 0.7 6.65 0.51 8.51e-10 Vitiligo; TGCT cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg17264618 chr3:40429014 ENTPD3 0.31 4.54 0.38 1.32e-5 Renal cell carcinoma; TGCT cis rs7937682 0.889 rs12360825 chr11:111528786 A/T cg09085632 chr11:111637200 PPP2R1B -1.03 -10.02 -0.67 1.15e-17 Primary sclerosing cholangitis; TGCT cis rs2439831 0.850 rs12441861 chr15:44060883 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs1371867 0.810 rs1692004 chr8:101247320 T/C cg00191853 chr8:101177733 SPAG1 0.23 4.55 0.38 1.29e-5 Atrioventricular conduction; TGCT cis rs854765 0.583 rs9913724 chr17:17819101 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.69 0.57 3.91e-12 Total body bone mineral density; TGCT cis rs769267 0.930 rs10282 chr19:19619317 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs6089584 0.528 rs4925334 chr20:60626769 C/T cg13770153 chr20:60521292 NA -0.43 -5.15 -0.42 9.9e-7 Body mass index; TGCT trans rs9650657 0.589 rs12542037 chr8:10758496 G/A cg15556689 chr8:8085844 FLJ10661 0.81 7.52 0.56 9.58e-12 Neuroticism; TGCT cis rs2013441 1.000 rs2703801 chr17:20100600 T/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs8050907 0.744 rs9938647 chr16:4572151 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.58 4.74 0.39 5.67e-6 Obesity-related traits; TGCT cis rs4851254 0.695 rs12712069 chr2:100766354 C/G cg23118464 chr2:100721844 AFF3 0.6 4.5 0.37 1.56e-5 Intelligence (multi-trait analysis); TGCT cis rs6032067 0.516 rs2743334 chr20:43919745 A/G cg16667508 chr20:43936853 MATN4;RBPJL -0.39 -6.27 -0.49 5.39e-9 Blood protein levels; TGCT cis rs9674544 0.757 rs4410130 chr17:47122942 C/T cg07075026 chr17:47091521 IGF2BP1 0.43 4.5 0.37 1.54e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs7959452 0.640 rs12370042 chr12:69692420 C/G cg20891283 chr12:69753455 YEATS4 0.66 6.57 0.51 1.26e-9 Blood protein levels; TGCT cis rs13118159 0.934 rs4974608 chr4:1356780 C/T cg13395646 chr4:1353034 KIAA1530 -0.38 -4.57 -0.38 1.16e-5 Longevity; TGCT cis rs3733585 0.578 rs4466042 chr4:9955367 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs208520 0.690 rs207096 chr6:66797287 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.83 -0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs2836974 0.796 rs77153312 chr21:40695499 G/A cg06238570 chr21:40685208 BRWD1 0.7 6.09 0.48 1.34e-8 Cognitive function; TGCT cis rs2228479 0.850 rs12597299 chr16:89822364 C/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg02458000 chr6:26745757 NA -0.5 -4.55 -0.38 1.24e-5 Schizophrenia; TGCT cis rs9902453 1.000 rs28664971 chr17:28437410 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.31 0.55 2.88e-11 Coffee consumption (cups per day); TGCT cis rs67311347 0.910 rs7617361 chr3:40373259 G/T cg13683864 chr3:40499215 RPL14 -0.98 -10.09 -0.67 7.74e-18 Renal cell carcinoma; TGCT cis rs7904368 0.806 rs4612698 chr10:16855070 C/A cg14835575 chr10:16859367 RSU1 0.7 7.48 0.56 1.19e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs6906287 0.625 rs9489355 chr6:118685314 A/G cg21191810 chr6:118973309 C6orf204 0.27 4.58 0.38 1.11e-5 Electrocardiographic conduction measures; TGCT cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Vitiligo; TGCT cis rs1008375 0.966 rs6832962 chr4:17652133 T/C cg10189774 chr4:17578691 LAP3 0.53 4.6 0.38 1.04e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs288326 0.561 rs77318535 chr2:183857319 C/T cg09997497 chr2:183902928 NCKAP1 1.12 4.86 0.4 3.52e-6 Blood protein levels; TGCT cis rs8062405 0.558 rs151228 chr16:28563026 A/G cg09754948 chr16:28834200 ATXN2L 0.55 4.54 0.38 1.3e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT trans rs561341 0.769 rs7217004 chr17:30178092 A/G cg20587970 chr11:113659929 NA 0.89 9.02 0.63 2.99e-15 Hip circumference adjusted for BMI; TGCT cis rs2439831 1.000 rs2253708 chr15:43797273 G/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.11 0.59 4.19e-13 Lung cancer in ever smokers; TGCT cis rs9486719 0.948 rs11153059 chr6:97014537 T/A cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs854765 0.583 rs7214536 chr17:17852446 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs17376456 0.877 rs9314093 chr5:93333347 G/A cg21475434 chr5:93447410 FAM172A 0.63 4.77 0.39 5.14e-6 Diabetic retinopathy; TGCT cis rs7772486 0.686 rs6933161 chr6:146081369 G/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.7 -0.39 6.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs17767294 0.708 rs72848774 chr6:27945640 C/T cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs6964587 1.000 rs13231578 chr7:91663266 C/T cg17063962 chr7:91808500 NA 0.87 9.41 0.65 3.46e-16 Breast cancer; TGCT cis rs7267979 1.000 rs4815426 chr20:25405186 A/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1635 0.826 rs7750106 chr6:28223680 C/A cg15743358 chr6:28303923 ZNF323 -1.1 -4.55 -0.38 1.25e-5 Schizophrenia; TGCT cis rs12468226 0.752 rs116078354 chr2:203001079 T/C cg26506821 chr2:202639771 ALS2 0.35 4.49 0.37 1.61e-5 Urate levels; TGCT cis rs2579519 0.515 rs4907278 chr2:96392196 C/T cg23100626 chr2:96804247 ASTL 0.46 5.68 0.45 9.16e-8 Diastolic blood pressure; TGCT cis rs854765 0.693 rs11657074 chr17:17770355 G/A cg09796270 chr17:17721594 SREBF1 -0.28 -5.63 -0.45 1.13e-7 Total body bone mineral density; TGCT cis rs9581857 0.615 rs61622854 chr13:28023194 T/A cg22138327 chr13:27999177 GTF3A 0.71 5.12 0.42 1.16e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs2456568 0.503 rs4254038 chr11:93666978 T/C cg26875233 chr11:93583750 C11orf90 -0.44 -5.2 -0.42 8.13e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs2760061 0.784 rs708116 chr1:228198196 C/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.08 -0.54 9.57e-11 Diastolic blood pressure; TGCT cis rs12971120 0.891 rs11151960 chr18:72177232 G/A cg25817165 chr18:72167213 CNDP2 -0.27 -4.65 -0.39 8.37e-6 Refractive error; TGCT cis rs7523273 0.568 rs61821293 chr1:208007277 T/G cg22525895 chr1:207977042 MIR29B2 -0.43 -6.24 -0.49 6.48e-9 Schizophrenia; TGCT trans rs916888 0.773 rs199533 chr17:44828931 G/A cg22968622 chr17:43663579 NA 1.31 11.93 0.73 2.49e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4780401 0.588 rs8191298 chr16:11767055 C/A cg01061890 chr16:11836724 TXNDC11 -0.46 -4.5 -0.37 1.52e-5 Rheumatoid arthritis; TGCT cis rs9910055 0.659 rs2251165 chr17:42234748 T/C cg13607699 chr17:42295918 UBTF 0.59 5.44 0.44 2.67e-7 Total body bone mineral density; TGCT cis rs4478858 0.684 rs4949374 chr1:31754511 G/C cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs5769765 0.720 rs138820 chr22:50164078 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.97 -9.21 -0.64 1.01e-15 Schizophrenia; TGCT cis rs752010 0.746 rs10890146 chr1:42089389 G/A cg06885757 chr1:42089581 HIVEP3 0.25 4.56 0.38 1.23e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs11098499 0.780 rs10013652 chr4:120292256 A/G cg09307838 chr4:120376055 NA 0.55 5.41 0.44 3.07e-7 Corneal astigmatism; TGCT cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg17971929 chr21:40555470 PSMG1 -0.68 -5.82 -0.46 4.81e-8 Cognitive function; TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg01802117 chr1:53393560 SCP2 0.48 5.76 0.46 6.16e-8 Monocyte count; TGCT cis rs4478037 1.000 rs58995409 chr3:33161404 T/C cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg16524733 chr11:117070046 TAGLN 0.31 4.46 0.37 1.81e-5 Blood protein levels; TGCT cis rs4595586 0.546 rs11609849 chr12:39258090 C/G cg13010199 chr12:38710504 ALG10B 0.62 4.9 0.4 2.99e-6 Morning vs. evening chronotype; TGCT cis rs1801251 1.000 rs283469 chr2:233656997 G/T cg08000102 chr2:233561755 GIGYF2 0.63 6.34 0.49 3.84e-9 Coronary artery disease; TGCT cis rs1577917 0.958 rs36042496 chr6:86524214 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs11190604 0.767 rs74869390 chr10:102189385 A/G cg16005271 chr10:102321736 NA 0.46 4.67 0.39 7.62e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs929354 0.772 rs2366214 chr7:156992461 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs67460515 0.892 rs35100811 chr3:161084046 A/C cg03342759 chr3:160939853 NMD3 -0.52 -5.38 -0.44 3.56e-7 Parkinson's disease; TGCT cis rs2836974 0.836 rs1041440 chr21:40627325 C/T cg11644478 chr21:40555479 PSMG1 1.0 10.69 0.69 2.7e-19 Cognitive function; TGCT cis rs7772486 0.686 rs9390357 chr6:146129347 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.68e-16 Lobe attachment (rater-scored or self-reported); TGCT trans rs1496653 0.602 rs13091634 chr3:23509363 T/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT trans rs7824557 0.518 rs11783749 chr8:10802055 G/A cg15556689 chr8:8085844 FLJ10661 -0.82 -7.42 -0.55 1.66e-11 Retinal vascular caliber; TGCT cis rs1153858 0.621 rs1719237 chr15:45579822 G/A cg26924012 chr15:45694286 SPATA5L1 1.0 10.91 0.7 7.59e-20 Homoarginine levels; TGCT cis rs9611565 0.559 rs12483860 chr22:41961916 C/T cg13695892 chr22:41940480 POLR3H -0.87 -8.17 -0.59 2.95e-13 Vitiligo; TGCT cis rs6450176 1.000 rs3776716 chr5:53298923 A/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs17376456 0.877 rs35747258 chr5:93310129 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg20999797 chr1:1681921 NA 0.19 4.85 0.4 3.68e-6 Body mass index; TGCT cis rs1218582 0.710 rs9794000 chr1:154878876 T/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.12 -0.54 7.57e-11 Prostate cancer; TGCT cis rs137603 0.644 rs137621 chr22:39710244 G/A cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.75 -0.39 5.59e-6 Primary biliary cholangitis; TGCT cis rs362272 0.525 rs910568 chr4:3307373 A/G cg18352616 chr4:3374830 RGS12 0.23 4.47 0.37 1.73e-5 Serum sulfate level; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg07205460 chr22:24236375 MIF 0.61 4.81 0.4 4.21e-6 S-phenylmercapturic acid levels in smokers; TGCT cis rs7666738 0.830 rs13136930 chr4:98937933 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.15e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9549260 0.755 rs2721069 chr13:41143720 C/T cg21288729 chr13:41239152 FOXO1 0.98 10.08 0.67 8.21e-18 Red blood cell count; TGCT trans rs208515 0.560 rs207084 chr6:66776966 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.07 -15.79 -0.82 1.83e-31 Exhaled nitric oxide levels; TGCT cis rs17253792 0.822 rs76819679 chr14:56134672 C/G cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs73198271 0.694 rs113694763 chr8:8647076 C/T cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7312933 0.558 rs4768402 chr12:42755576 A/G cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.18e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs858239 0.539 rs870476 chr7:23193271 C/T cg05602783 chr7:23145260 KLHL7 -0.59 -4.8 -0.4 4.46e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs1348850 0.519 rs1527407 chr2:178525630 T/G cg22681709 chr2:178499509 PDE11A -0.48 -6.08 -0.48 1.36e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs6121246 0.529 rs73235789 chr20:30196148 T/C cg18721089 chr20:30220636 NA -0.57 -6.19 -0.49 7.9e-9 Mean corpuscular hemoglobin; TGCT cis rs8033133 0.881 rs4344720 chr15:25324141 C/T cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.26 -4.91 -0.4 2.8e-6 Blood osmolality (transformed sodium); TGCT cis rs1005277 0.579 rs1548255 chr10:38417193 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -7.97 -0.58 8.65e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9399135 0.660 rs4472368 chr6:135274232 A/G cg24558204 chr6:135376177 HBS1L 0.5 5.21 0.42 7.48e-7 Red blood cell count; TGCT cis rs2742234 0.794 rs17153156 chr10:43704637 C/G cg02780029 chr10:43622663 RET 0.25 4.92 0.4 2.72e-6 Hirschsprung disease; TGCT cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg03452623 chr4:187889614 NA -0.35 -5.36 -0.43 3.87e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7246657 0.943 rs6508733 chr19:38000548 A/T cg18154014 chr19:37997991 ZNF793 0.73 5.43 0.44 2.85e-7 Coronary artery calcification; TGCT cis rs7666738 0.791 rs28579101 chr4:98843203 T/C cg17366294 chr4:99064904 C4orf37 0.72 7.5 0.56 1.07e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs115226628 chr4:119639818 A/G cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs7552404 0.727 rs4949677 chr1:76266662 T/A cg22875332 chr1:76189707 ACADM 0.64 6.81 0.52 3.82e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs986417 1.000 rs6573318 chr14:61087985 A/G cg27398547 chr14:60952738 C14orf39 1.56 8.38 0.6 9.49e-14 Gut microbiota (bacterial taxa); TGCT cis rs7726839 0.561 rs56410216 chr5:583216 C/A cg09021430 chr5:549028 NA -0.37 -5.23 -0.42 7.12e-7 Obesity-related traits; TGCT cis rs11190604 1.000 rs10883504 chr10:102280687 G/A cg16342193 chr10:102329863 NA -0.43 -5.68 -0.45 8.95e-8 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6088590 0.735 rs6060001 chr20:33294353 C/T cg06115741 chr20:33292138 TP53INP2 -0.55 -4.69 -0.39 6.99e-6 Coronary artery disease; TGCT cis rs9303401 0.659 rs7223708 chr17:56896398 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs62244186 0.748 rs12635624 chr3:44678498 G/A cg02073558 chr3:44770973 ZNF501 0.64 6.25 0.49 5.97e-9 Depressive symptoms; TGCT cis rs11105298 0.891 rs10858871 chr12:89871613 G/A cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6674176 0.597 rs2352990 chr1:44393276 T/A cg12908607 chr1:44402522 ARTN -0.76 -9.36 -0.64 4.58e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1670533 0.932 rs11731289 chr4:1057773 T/G cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs2013441 1.000 rs2703804 chr17:20107195 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs137603 1.000 rs137603 chr22:39694225 A/C cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -5.04 -0.41 1.61e-6 Primary biliary cholangitis; TGCT cis rs2046867 0.818 rs6808341 chr3:72914847 A/G cg25664220 chr3:72788482 NA -0.54 -7.29 -0.55 3.23e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs939658 0.776 rs68147688 chr15:79443848 G/A cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT trans rs797680 0.964 rs624131 chr1:93683210 A/G cg27528825 chr2:159282178 CCDC148 0.34 6.7 0.52 6.63e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6860806 0.507 rs2631372 chr5:131703578 C/G cg24060327 chr5:131705240 SLC22A5 -0.63 -4.98 -0.41 2.05e-6 Breast cancer; TGCT cis rs71636778 0.509 rs61457762 chr1:27284157 C/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg06634786 chr22:41940651 POLR3H -0.85 -7.92 -0.58 1.12e-12 Vitiligo; TGCT cis rs11673344 0.543 rs12980849 chr19:37651714 C/T cg08039142 chr19:36980659 ZNF566 0.49 4.49 0.37 1.63e-5 Obesity-related traits; TGCT cis rs2153535 0.563 rs3117071 chr6:8537908 C/T cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2933343 0.859 rs789245 chr3:128583580 C/A cg11901034 chr3:128598214 ACAD9 -0.62 -5.16 -0.42 9.47e-7 IgG glycosylation; TGCT cis rs1847202 0.859 rs6805260 chr3:72933767 C/T cg25664220 chr3:72788482 NA -0.36 -4.52 -0.38 1.41e-5 Motion sickness; TGCT cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg16049864 chr8:95962084 TP53INP1 -0.77 -11.21 -0.71 1.44e-20 Type 2 diabetes; TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg02493798 chr17:6899577 ALOX12 0.43 4.74 0.39 5.77e-6 Tonsillectomy; TGCT cis rs6987853 0.931 rs2923444 chr8:42397004 C/T cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs2688608 0.620 rs12253408 chr10:75495956 G/T cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs7843479 0.965 rs2291317 chr8:21827162 C/T cg17168535 chr8:21777572 XPO7 0.68 6.46 0.5 2.2e-9 Mean corpuscular volume; TGCT cis rs11098499 0.866 rs9995136 chr4:120286845 A/G cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs539096 0.540 rs3011219 chr1:44306120 A/G cg12908607 chr1:44402522 ARTN -0.68 -8.12 -0.59 3.97e-13 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg17971929 chr21:40555470 PSMG1 -0.52 -4.64 -0.38 8.72e-6 Menarche (age at onset); TGCT cis rs72945132 0.882 rs17853270 chr11:70200529 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs16867321 0.694 rs11889207 chr2:181424527 A/C cg23363182 chr2:181467187 NA -0.38 -5.76 -0.46 6.36e-8 Obesity; TGCT cis rs6088580 0.634 rs4911423 chr20:32999386 T/A cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs12220238 0.915 rs11001020 chr10:76139217 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.21 0.49 7.5e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4919694 0.572 rs7080935 chr10:104929113 C/A cg04362960 chr10:104952993 NT5C2 0.97 6.81 0.52 3.82e-10 Arsenic metabolism; TGCT cis rs2738048 0.545 rs2978950 chr8:6825284 C/G cg24860332 chr8:6827800 DEFA10P -0.44 -6.38 -0.5 3.19e-9 IgA nephropathy; TGCT cis rs8031584 0.752 rs7174744 chr15:31183747 G/A cg08704250 chr15:31115839 NA 0.38 5.63 0.45 1.12e-7 Huntington's disease progression; TGCT cis rs9814567 0.964 rs12492930 chr3:134222722 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2692947 0.537 rs1834135 chr2:96244225 C/A cg23100626 chr2:96804247 ASTL 0.41 4.65 0.39 8.45e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6693567 0.545 rs35705743 chr1:150451832 G/A cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Migraine; TGCT cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg00814883 chr7:100076585 TSC22D4 -0.82 -8.37 -0.6 1.03e-13 Platelet count; TGCT cis rs981844 0.796 rs13140722 chr4:154712203 T/A cg14289246 chr4:154710475 SFRP2 -1.08 -10.27 -0.68 2.72e-18 Response to statins (LDL cholesterol change); TGCT trans rs1005277 0.579 rs2505196 chr10:38393563 G/A cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs7904368 0.754 rs7076955 chr10:16852781 G/A cg14835575 chr10:16859367 RSU1 0.69 7.72 0.57 3.32e-12 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs4665809 1.000 rs4233710 chr2:26291565 G/A cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs7659604 0.540 rs9995322 chr4:122675642 G/A cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs77948430 0.581 rs76016166 chr8:13157068 C/G cg25598624 chr8:12235727 FAM66A 0.31 4.53 0.38 1.36e-5 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs854765 0.583 rs8078138 chr17:17811251 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.91 0.58 1.2e-12 Total body bone mineral density; TGCT cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg08859206 chr1:53392774 SCP2 0.39 5.79 0.46 5.41e-8 Monocyte count; TGCT cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2456568 0.867 rs2462750 chr11:93668590 C/T cg17595323 chr11:93583763 C11orf90 -0.46 -5.79 -0.46 5.39e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT trans rs1470506 0.507 rs55985303 chr2:77224951 G/A cg15576869 chr7:50450374 IKZF1 -0.41 -6.76 -0.52 4.74e-10 IgG glycosylation; TGCT cis rs9911578 0.839 rs7208505 chr17:57187729 C/T cg12560992 chr17:57184187 TRIM37 0.72 8.6 0.61 2.98e-14 Intelligence (multi-trait analysis); TGCT cis rs826838 1.000 rs11168676 chr12:38977304 A/G cg13010199 chr12:38710504 ALG10B 0.8 6.77 0.52 4.58e-10 Heart rate; TGCT cis rs1215050 0.846 rs1839903 chr4:98791414 C/T cg05340658 chr4:99064831 C4orf37 0.46 5.51 0.44 1.94e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2841277 0.708 rs28454709 chr14:105405942 G/A cg19901468 chr14:105411992 AHNAK2 -0.28 -6.09 -0.48 1.31e-8 Rheumatoid arthritis; TGCT cis rs9467711 0.606 rs34273322 chr6:26415409 T/A cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs909674 0.818 rs8136980 chr22:39844574 G/A cg11247378 chr22:39784982 NA -0.73 -9.24 -0.64 8.56e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs35000415 0.938 rs13227075 chr7:128643297 T/C cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg09222892 chr1:25734099 RHCE -0.43 -6.9 -0.53 2.4e-10 Erythrocyte sedimentation rate; TGCT cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg02073558 chr3:44770973 ZNF501 0.56 5.48 0.44 2.25e-7 Depressive symptoms; TGCT cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg06481639 chr22:41940642 POLR3H -0.76 -7.05 -0.54 1.08e-10 Vitiligo; TGCT cis rs11098499 0.874 rs10022508 chr4:120115228 A/G cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs73198271 0.653 rs10099808 chr8:8659873 A/G cg06636001 chr8:8085503 FLJ10661 0.61 4.53 0.38 1.38e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg21226059 chr5:178986404 RUFY1 0.49 5.31 0.43 4.79e-7 Lung cancer; TGCT cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs992157 0.735 rs10932765 chr2:219099484 T/C cg00012203 chr2:219082015 ARPC2 0.81 10.21 0.68 3.88e-18 Colorectal cancer; TGCT cis rs9549260 0.755 rs2701863 chr13:41170140 C/T cg21288729 chr13:41239152 FOXO1 1.0 10.06 0.67 9.29e-18 Red blood cell count; TGCT cis rs1395 0.925 rs2580754 chr2:27398196 A/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.49 6.7 0.52 6.55e-10 Blood metabolite levels; TGCT cis rs11864453 0.647 rs3852781 chr16:72123556 T/A cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs9560113 0.960 rs61967677 chr13:112174044 A/G cg14154082 chr13:112174009 NA 0.34 4.58 0.38 1.09e-5 Menarche (age at onset); TGCT trans rs2727020 0.553 rs3907576 chr11:49536639 A/C cg15704280 chr7:45808275 SEPT13 -0.61 -6.81 -0.52 3.77e-10 Coronary artery disease; TGCT cis rs7731657 0.537 rs72801793 chr5:130376936 A/T cg08523029 chr5:130500466 HINT1 -0.61 -5.05 -0.41 1.55e-6 Fasting plasma glucose; TGCT cis rs1971762 0.583 rs2365345 chr12:54086820 C/T cg16917193 chr12:54089295 NA 1.39 18.43 0.86 2.53e-37 Height; TGCT cis rs9640161 0.742 rs2108851 chr7:150019634 T/C cg10018233 chr7:150070692 REPIN1 0.33 4.74 0.39 5.68e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs9325144 0.555 rs1973292 chr12:38679626 T/C cg26384229 chr12:38710491 ALG10B 0.66 6.13 0.48 1.09e-8 Morning vs. evening chronotype; TGCT cis rs6545883 0.929 rs6705235 chr2:61713580 G/C cg15711740 chr2:61764176 XPO1 -0.57 -5.2 -0.42 7.85e-7 Tuberculosis; TGCT cis rs9549367 0.789 rs2287247 chr13:113889212 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.49 -0.44 2.18e-7 Platelet distribution width; TGCT cis rs1372520 0.684 rs2619368 chr4:90729747 T/G cg15133208 chr4:90757351 SNCA -0.52 -6.07 -0.48 1.44e-8 Neuroticism; TGCT cis rs28595532 0.841 rs114465037 chr4:119778165 A/G cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs10751667 0.666 rs10902243 chr11:949900 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs78487399 0.808 rs17030800 chr2:43671003 C/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.09 -0.42 1.3e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs832540 0.552 rs252924 chr5:56205643 A/G cg20203395 chr5:56204925 C5orf35 -0.52 -4.58 -0.38 1.12e-5 Coronary artery disease; TGCT trans rs66573146 0.831 rs67315413 chr4:6987910 T/C cg07817883 chr1:32538562 TMEM39B 1.3 6.83 0.52 3.41e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg11502198 chr6:26597334 ABT1 0.51 4.61 0.38 9.7e-6 Intelligence (multi-trait analysis); TGCT cis rs9915657 0.715 rs34126003 chr17:70106615 G/T cg06234051 chr17:70120541 SOX9 -0.24 -5.14 -0.42 1.03e-6 Thyroid hormone levels; TGCT cis rs1371867 0.875 rs1660320 chr8:101337579 A/C cg00191853 chr8:101177733 SPAG1 -0.23 -4.73 -0.39 6.08e-6 Atrioventricular conduction; TGCT cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg11279151 chr3:101281821 RG9MTD1 -0.35 -7.28 -0.55 3.4e-11 Colorectal cancer; TGCT cis rs7267979 0.903 rs6115118 chr20:25246734 G/A cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9660180 0.967 rs6603803 chr1:1812688 A/G cg13866156 chr1:1669148 SLC35E2 -0.21 -5.13 -0.42 1.09e-6 Body mass index; TGCT cis rs4891159 0.513 rs2554831 chr18:74113513 C/G cg24786174 chr18:74118243 ZNF516 0.7 14.77 0.8 4.27e-29 Longevity; TGCT cis rs28595532 1.000 rs17258106 chr4:119675406 C/T cg14228332 chr4:119757509 SEC24D -1.04 -6.06 -0.48 1.52e-8 Cannabis dependence symptom count; TGCT cis rs7824557 0.628 rs3779891 chr8:11183505 G/A cg21775007 chr8:11205619 TDH 0.66 6.47 0.5 2.08e-9 Retinal vascular caliber; TGCT cis rs763121 0.719 rs9610995 chr22:39057763 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.9e-12 Menopause (age at onset); TGCT cis rs2692947 0.637 rs1168967 chr2:96826016 A/G cg23100626 chr2:96804247 ASTL 0.44 5.25 0.43 6.37e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs734999 0.545 rs28690427 chr1:2571823 A/G cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs4629710 0.592 rs4424112 chr6:131563788 C/T cg12606694 chr6:131520996 AKAP7 0.41 4.82 0.4 4.09e-6 Multiple myeloma (IgH translocation); TGCT cis rs11105298 0.891 rs11105319 chr12:89927177 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.69 -4.96 -0.41 2.3e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9837602 0.507 rs1718244 chr3:99512608 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.5 0.5 1.78e-9 Breast cancer; TGCT cis rs6671200 0.850 rs259345 chr1:95729649 A/G cg20701556 chr1:95698924 RWDD3 -0.67 -5.63 -0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs1371867 0.846 rs1660312 chr8:101330634 C/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.3 -0.49 4.66e-9 Atrioventricular conduction; TGCT cis rs4285028 0.948 rs6790281 chr3:121665543 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs4081724 0.565 rs73024301 chr19:33803191 C/T cg18823272 chr19:34111733 CHST8 0.4 4.5 0.37 1.52e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1371867 0.846 rs1788197 chr8:101290928 T/C cg06002616 chr8:101225028 SPAG1 -0.53 -6.42 -0.5 2.67e-9 Atrioventricular conduction; TGCT cis rs13242816 1.000 rs17138767 chr7:116137677 A/G cg02799643 chr7:116139180 CAV2 -0.46 -5.92 -0.47 3e-8 P wave duration; TGCT cis rs526231 0.575 rs26822 chr5:102518795 A/G cg23492399 chr5:102201601 PAM -0.5 -4.49 -0.37 1.6e-5 Primary biliary cholangitis; TGCT cis rs4383453 0.539 rs16834218 chr3:123097988 T/C cg04890266 chr3:123102914 ADCY5 -0.5 -8.34 -0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs11690935 0.632 rs62183783 chr2:172865775 A/G cg13550731 chr2:172543902 DYNC1I2 0.6 5.23 0.43 7e-7 Schizophrenia; TGCT cis rs10067451 0.606 rs17419291 chr5:87780432 C/T cg24804195 chr5:87968844 LOC645323 -1.22 -4.67 -0.39 7.7e-6 Photic sneeze reflex; TGCT cis rs12497850 1.000 rs1352420 chr3:48757291 A/G cg18654377 chr3:49208889 KLHDC8B -0.43 -5.71 -0.46 8.06e-8 Parkinson's disease; TGCT cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg10295955 chr4:187884368 NA -0.99 -15.24 -0.81 3.38e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs2657888 1.000 rs2657901 chr12:56933416 A/G cg23002907 chr12:56915593 RBMS2 0.44 6.15 0.48 9.65e-9 Adiponectin levels; TGCT cis rs9611565 0.503 rs5751156 chr22:42170025 A/G cg17554472 chr22:41940697 POLR3H 0.45 4.64 0.38 8.54e-6 Vitiligo; TGCT cis rs7772486 0.902 rs1331643 chr6:146398873 T/A cg23711669 chr6:146136114 FBXO30 0.79 8.32 0.6 1.37e-13 Lobe attachment (rater-scored or self-reported); TGCT cis rs12950390 0.893 rs12325760 chr17:45840886 C/T cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.6e-6 IgG glycosylation; TGCT cis rs7659604 0.540 rs7698889 chr4:122671324 G/T cg19748678 chr4:122722346 EXOSC9 -0.51 -4.93 -0.4 2.58e-6 Type 2 diabetes; TGCT cis rs11992186 0.570 rs17628941 chr8:8587534 G/C cg06636001 chr8:8085503 FLJ10661 -0.58 -4.87 -0.4 3.32e-6 Neuroticism; TGCT cis rs7582180 0.591 rs1030902 chr2:101007178 T/G cg08017756 chr2:100939284 LONRF2 -0.31 -5.07 -0.41 1.4e-6 Intelligence (multi-trait analysis); TGCT cis rs916888 0.821 rs199507 chr17:44858855 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3803170 0.513 rs7302763 chr12:111827569 C/T cg10833066 chr12:111807467 FAM109A 0.36 5.11 0.42 1.17e-6 Mean corpuscular hemoglobin; TGCT trans rs2727020 0.595 rs10839281 chr11:49483373 A/C cg11707556 chr5:10655725 ANKRD33B -0.35 -6.79 -0.52 4.14e-10 Coronary artery disease; TGCT cis rs11587400 0.572 rs2268697 chr1:115227493 A/G cg12756093 chr1:115239321 AMPD1 0.32 4.56 0.38 1.23e-5 Autism; TGCT cis rs1218582 0.804 rs4845678 chr1:154853295 A/G cg09359103 chr1:154839909 KCNN3 -0.65 -12.04 -0.73 1.35e-22 Prostate cancer; TGCT cis rs826838 1.000 rs11183214 chr12:38692938 C/T cg26384229 chr12:38710491 ALG10B 1.12 11.32 0.71 7.88e-21 Heart rate; TGCT cis rs7568458 0.905 rs10198569 chr2:85794415 C/T cg17127132 chr2:85788382 GGCX -0.69 -6.13 -0.48 1.09e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7818688 0.697 rs11787303 chr8:95972864 C/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs981844 0.922 rs2118863 chr4:154657579 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT trans rs9467711 1.000 rs9467704 chr6:26319486 A/G cg20516262 chr7:155325649 CNPY1 -0.56 -6.89 -0.53 2.46e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs2562456 0.834 rs2173727 chr19:21673957 C/T cg25650185 chr19:21324782 ZNF431 0.58 5.04 0.41 1.6e-6 Pain; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg01238044 chr22:24384105 GSTT1 0.58 5.62 0.45 1.18e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT trans rs2727020 0.729 rs1164666 chr11:49295867 C/T cg03929089 chr4:120376271 NA -0.72 -8.3 -0.6 1.48e-13 Coronary artery disease; TGCT cis rs7412746 0.611 rs9661876 chr1:150910911 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs7824557 0.751 rs2099456 chr8:11127001 A/C cg21775007 chr8:11205619 TDH 0.6 5.97 0.47 2.37e-8 Retinal vascular caliber; TGCT cis rs875971 1.000 rs6961717 chr7:65587537 C/T cg18876405 chr7:65276391 NA -0.33 -5.02 -0.41 1.72e-6 Aortic root size; TGCT cis rs67311347 0.955 rs6764102 chr3:40378153 C/G cg13683864 chr3:40499215 RPL14 -1.09 -11.46 -0.72 3.52e-21 Renal cell carcinoma; TGCT cis rs7394190 0.748 rs4746146 chr10:75527197 C/T cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.48e-6 Incident atrial fibrillation; TGCT cis rs2832191 0.967 rs3787660 chr21:30520907 C/T cg08807101 chr21:30365312 RNF160 0.53 4.97 0.41 2.19e-6 Dental caries; TGCT cis rs2066819 1.000 rs57279772 chr12:56698960 G/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs2295359 0.637 rs12044149 chr1:67600686 G/T cg12940439 chr1:67600707 NA 0.7 7.22 0.54 4.5e-11 Psoriasis; TGCT cis rs1005277 0.505 rs7917943 chr10:38195811 T/A cg25427524 chr10:38739819 LOC399744 0.37 7.61 0.56 5.93e-12 Extrinsic epigenetic age acceleration; TGCT cis rs514406 0.584 rs11205997 chr1:53195271 G/C cg25767906 chr1:53392781 SCP2 0.44 4.79 0.4 4.68e-6 Monocyte count; TGCT cis rs10089 1.000 rs3805607 chr5:127477418 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.7e-13 Ileal carcinoids; TGCT cis rs72949976 0.707 rs62186571 chr2:214038673 C/G cg08319019 chr2:214017104 IKZF2 -0.75 -6.35 -0.5 3.78e-9 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs11190604 1.000 rs7905961 chr10:102297391 G/C cg23241863 chr10:102295624 HIF1AN 0.72 5.33 0.43 4.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6558530 0.666 rs7845723 chr8:1697086 T/G cg09410841 chr8:1729607 CLN8 0.67 6.0 0.47 2.05e-8 Systolic blood pressure; TGCT cis rs17445774 1.000 rs1509833 chr2:200865225 G/A cg23649088 chr2:200775458 C2orf69 0.51 7.91 0.58 1.24e-12 LDL cholesterol to HDL cholesterol ratio; TGCT cis rs4253772 0.745 rs78023664 chr22:46647844 G/A cg09491104 chr22:46646882 C22orf40 -0.7 -4.59 -0.38 1.06e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs2404602 0.692 rs72738889 chr15:76992063 G/A cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs2836974 0.644 rs7281853 chr21:40693490 A/G cg11890956 chr21:40555474 PSMG1 -0.71 -6.72 -0.52 5.82e-10 Cognitive function; TGCT cis rs7809950 0.559 rs2248465 chr7:107303628 C/T cg23024343 chr7:107201750 COG5 0.34 4.95 0.41 2.4e-6 Coronary artery disease; TGCT cis rs7772486 0.754 rs2328707 chr6:146053498 G/A cg05347473 chr6:146136440 FBXO30 -0.51 -4.66 -0.39 8.17e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs854765 0.583 rs4553680 chr17:17857722 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.86 0.58 1.58e-12 Total body bone mineral density; TGCT cis rs2658782 1.000 rs2019814 chr11:93168885 A/G cg18152523 chr11:93063302 CCDC67 -0.64 -5.15 -0.42 9.9e-7 Pulmonary function decline; TGCT cis rs4851266 1.000 rs4851266 chr2:100818479 C/T cg07810366 chr2:100720526 AFF3 -0.39 -5.59 -0.45 1.37e-7 Educational attainment; TGCT cis rs1971762 0.527 rs7952858 chr12:54039692 C/G cg16917193 chr12:54089295 NA 1.04 11.29 0.71 8.98e-21 Height; TGCT cis rs72634258 0.554 rs10462018 chr1:7879627 C/T cg26816564 chr1:7831052 VAMP3 0.84 6.29 0.49 5e-9 Inflammatory bowel disease; TGCT cis rs8062405 1.000 rs62036620 chr16:28833097 A/G cg09754948 chr16:28834200 ATXN2L 0.61 4.54 0.38 1.34e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg06873352 chr17:61820015 STRADA 0.59 6.44 0.5 2.37e-9 Prudent dietary pattern; TGCT cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg12310025 chr6:25882481 NA 0.52 5.19 0.42 8.4e-7 Blood metabolite levels; TGCT trans rs3780486 0.846 rs10813960 chr9:33180362 C/T cg20290983 chr6:43655470 MRPS18A 1.08 11.36 0.71 6.12e-21 IgG glycosylation; TGCT cis rs7647973 0.710 rs6797299 chr3:49609794 G/T cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs7095607 0.606 rs6480313 chr10:69957928 C/T cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs2456568 0.548 rs7105031 chr11:93661207 C/T cg26875233 chr11:93583750 C11orf90 -0.41 -4.94 -0.41 2.43e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9916302 0.904 rs7221875 chr17:37543328 G/A cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs28595532 0.920 rs115986613 chr4:119752156 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7027203 0.828 rs4744287 chr9:96585567 A/G cg14396892 chr9:96623032 NA 0.29 6.25 0.49 6.02e-9 DNA methylation (variation); TGCT cis rs1552244 0.935 rs66493421 chr3:10092569 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.0 6.2 0.49 7.85e-9 Alzheimer's disease; TGCT cis rs5769765 0.773 rs138861 chr22:50202276 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.33 4.84 0.4 3.85e-6 Schizophrenia; TGCT cis rs4523957 0.614 rs7208638 chr17:2061334 G/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7681440 0.647 rs11941682 chr4:90804316 T/G cg20003494 chr4:90757398 SNCA -0.53 -4.71 -0.39 6.56e-6 Dementia with Lewy bodies; TGCT cis rs7666738 0.830 rs6818045 chr4:99049374 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs877282 0.583 rs11253441 chr10:828288 C/T cg22713356 chr15:30763199 NA -0.9 -6.84 -0.52 3.22e-10 Uric acid levels; TGCT cis rs9357506 1.000 rs4714924 chr6:46304015 A/T cg21115430 chr6:46460003 NA -0.27 -5.07 -0.41 1.41e-6 Body mass index; TGCT cis rs7772486 0.875 rs2474353 chr6:146323883 G/A cg23711669 chr6:146136114 FBXO30 0.87 9.47 0.65 2.49e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs17152411 1.000 rs1807099 chr10:126593774 C/T cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs1218582 0.772 rs7528532 chr1:154874440 C/T cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs2268241 0.938 rs28653198 chr21:34782395 A/C cg14850771 chr21:34775459 IFNGR2 0.61 5.23 0.43 6.88e-7 Obesity-related traits; TGCT cis rs7085104 0.632 rs7097872 chr10:104606636 C/T cg04362960 chr10:104952993 NT5C2 0.56 4.92 0.4 2.68e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7618915 0.547 rs34610142 chr3:52708429 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs9611519 0.580 rs8138349 chr22:41412723 C/T cg03806693 chr22:41940476 POLR3H -0.64 -6.09 -0.48 1.29e-8 Neuroticism; TGCT cis rs8028182 0.636 rs4886716 chr15:75856022 G/C cg20655648 chr15:75932815 IMP3 0.59 4.49 0.37 1.62e-5 Sudden cardiac arrest; TGCT cis rs4665809 0.816 rs2384359 chr2:26371364 T/C cg25036284 chr2:26402008 FAM59B -0.55 -4.71 -0.39 6.45e-6 Gut microbiome composition (summer); TGCT cis rs892961 1.000 rs2117924 chr17:75401310 C/T cg05865280 chr17:75406074 SEPT9 0.28 6.57 0.51 1.22e-9 Airflow obstruction; TGCT cis rs9322193 0.923 rs9505826 chr6:149955048 A/G cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs5769765 1.000 rs8138941 chr22:50290678 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs9660180 0.967 rs6603803 chr1:1812688 A/G cg20999797 chr1:1681921 NA 0.18 4.61 0.38 9.89e-6 Body mass index; TGCT cis rs12142240 0.698 rs56284503 chr1:46847127 C/G cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT trans rs10203711 0.933 rs907110 chr2:239566391 C/T cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 0.546 rs7551944 chr1:210029430 G/C cg12034118 chr1:209979487 IRF6 0.65 4.54 0.38 1.31e-5 Cleft lip with or without cleft palate; TGCT cis rs10751667 0.643 rs7396623 chr11:934104 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs78487399 0.808 rs74365854 chr2:43661482 T/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.69 0.39 7.08e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs597539 0.518 rs35093305 chr11:68730729 A/G cg06028808 chr11:68637592 NA 0.56 7.27 0.55 3.51e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs17270561 0.779 rs12209218 chr6:25887776 C/A cg17042849 chr6:26104293 HIST1H4C -0.76 -5.36 -0.43 3.98e-7 Iron status biomarkers; TGCT cis rs2762353 0.595 rs12200838 chr6:25753603 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.64 7.0 0.53 1.43e-10 Blood metabolite levels; TGCT cis rs910316 1.000 rs4322591 chr14:75600697 C/T cg08847533 chr14:75593920 NEK9 0.96 10.86 0.7 1.05e-19 Height; TGCT cis rs899997 1.000 rs9888691 chr15:79010046 T/C cg04896959 chr15:78267971 NA 0.35 5.55 0.45 1.65e-7 Coronary artery disease or large artery stroke; TGCT cis rs4478858 0.698 rs6655946 chr1:31805728 G/A cg00250761 chr1:31883323 NA -0.27 -4.9 -0.4 2.92e-6 Alcohol dependence; TGCT cis rs6964587 0.655 rs6965864 chr7:91595596 A/G cg17063962 chr7:91808500 NA 0.75 7.1 0.54 8.68e-11 Breast cancer; TGCT cis rs916888 0.647 rs199449 chr17:44808902 G/A cg15921436 chr17:44337874 NA 0.44 6.62 0.51 9.8e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2404602 0.735 rs11072598 chr15:76764788 T/C cg22467129 chr15:76604101 ETFA 0.48 5.04 0.41 1.58e-6 Blood metabolite levels; TGCT cis rs9911578 1.000 rs7223955 chr17:56917053 C/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.500 rs2011053 chr22:42121278 G/A cg03806693 chr22:41940476 POLR3H 0.96 9.91 0.66 2.06e-17 Vitiligo; TGCT cis rs11696501 0.688 rs714595 chr20:44330591 G/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg03404566 chr17:6899310 ALOX12 -0.41 -4.83 -0.4 4.01e-6 Tonsillectomy; TGCT cis rs9952991 0.566 rs34846641 chr18:12875975 A/G cg23544223 chr18:12777786 NA -0.54 -4.81 -0.4 4.31e-6 Inflammatory skin disease; TGCT cis rs2033711 0.936 rs3794968 chr19:58986799 G/C cg12042659 chr19:58951599 ZNF132 0.52 4.53 0.38 1.39e-5 Uric acid clearance; TGCT trans rs797680 0.856 rs4240966 chr1:93774812 C/A cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs67478160 0.643 rs3742369 chr14:104251276 T/C cg26031613 chr14:104095156 KLC1 -0.63 -6.42 -0.5 2.64e-9 Schizophrenia; TGCT cis rs3733585 0.699 rs1079128 chr4:9951221 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.47 -0.56 1.25e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg18252515 chr7:66147081 NA -1.14 -6.81 -0.52 3.76e-10 Diabetic kidney disease; TGCT cis rs9296092 0.560 rs7765263 chr6:33525559 A/G cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg25703541 chr22:24373054 LOC391322 -0.81 -8.47 -0.61 6.1e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4148883 0.675 rs10015824 chr4:100074544 C/G cg12011299 chr4:100065546 ADH4 0.38 5.71 0.46 7.92e-8 Alcohol dependence; TGCT cis rs514406 0.861 rs4926577 chr1:53226788 C/A cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.29e-11 Monocyte count; TGCT cis rs12291225 0.679 rs11369 chr11:14288096 A/G cg19336497 chr11:14380999 RRAS2 -0.39 -6.01 -0.47 1.96e-8 Sense of smell; TGCT cis rs453301 0.653 rs1562211 chr8:8902424 A/G cg15556689 chr8:8085844 FLJ10661 -0.86 -8.12 -0.59 3.9e-13 Joint mobility (Beighton score); TGCT cis rs17461925 0.964 rs10920559 chr1:203035693 A/G cg21997465 chr1:203055662 MYOG -0.27 -4.57 -0.38 1.18e-5 Atrial fibrillation; TGCT cis rs6570726 0.791 rs11155433 chr6:145907831 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -4.85 -0.4 3.59e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg07424592 chr7:64974309 NA 1.33 8.82 0.62 8.94e-15 Diabetic kidney disease; TGCT cis rs9362426 0.672 rs12663865 chr6:88103149 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.46 4.86 0.4 3.53e-6 Depressive episodes in bipolar disorder; TGCT trans rs12339966 0.581 rs11789872 chr9:11332751 A/C cg03488587 chr11:64876988 C11orf2 0.32 7.03 0.53 1.19e-10 Systolic blood pressure; TGCT cis rs10875746 0.669 rs11168487 chr12:48640709 G/A cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs854765 0.583 rs6502622 chr17:17834691 A/G cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs7324557 0.683 rs9510868 chr13:24383694 A/G cg16602799 chr13:25254742 ATP12A 0.57 4.45 0.37 1.93e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs9733 0.519 rs11204717 chr1:150709129 T/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.87 0.4 3.27e-6 Tonsillectomy; TGCT cis rs17490626 0.568 rs12260685 chr10:71215799 C/T cg12610070 chr10:71211762 TSPAN15 -0.61 -6.95 -0.53 1.83e-10 Thrombosis; TGCT cis rs7786808 0.649 rs6459879 chr7:158211792 C/G cg01191920 chr7:158217561 PTPRN2 -0.37 -5.49 -0.44 2.16e-7 Obesity-related traits; TGCT cis rs2075671 0.903 rs62483570 chr7:100300649 C/T cg20848291 chr7:100343083 ZAN -0.52 -4.56 -0.38 1.21e-5 Other erythrocyte phenotypes; TGCT cis rs12210905 0.688 rs75968505 chr6:27476996 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7513165 0.932 rs12040580 chr1:204148168 T/C cg12731349 chr1:204159619 KISS1 0.47 5.4 0.44 3.2e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs9611565 0.649 rs5751144 chr22:42128097 A/G cg03806693 chr22:41940476 POLR3H -0.96 -9.91 -0.66 2.06e-17 Vitiligo; TGCT cis rs17030434 0.784 rs17370965 chr4:154650948 C/T cg14289246 chr4:154710475 SFRP2 -0.85 -7.14 -0.54 6.81e-11 Electrocardiographic conduction measures; TGCT cis rs10197940 0.624 rs3771901 chr2:152432481 G/A cg19508488 chr2:152266495 RIF1 0.7 6.5 0.5 1.77e-9 Lung cancer; TGCT cis rs11190604 1.000 rs3763695 chr10:102269206 A/G cg16342193 chr10:102329863 NA -0.38 -4.89 -0.4 3.06e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12477438 0.520 rs2171359 chr2:99795360 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs9486715 1.000 rs6905568 chr6:97066382 T/C cg06623918 chr6:96969491 KIAA0776 -1.08 -13.52 -0.77 3.67e-26 Headache; TGCT cis rs5750830 0.649 rs5750813 chr22:39795228 G/C cg24399712 chr22:39784796 NA -1.06 -12.52 -0.75 9.19e-24 Intelligence (multi-trait analysis); TGCT cis rs881375 0.678 rs7031752 chr9:123663482 G/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.41 4.72 0.39 6.38e-6 Rheumatoid arthritis; TGCT cis rs644799 0.526 rs506180 chr11:95623109 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.49 4.84 0.4 3.75e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs56399783 0.614 rs11772508 chr7:2771504 A/C cg19731401 chr7:2775893 GNA12 -0.35 -5.12 -0.42 1.13e-6 Childhood ear infection; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg06675538 chr2:114033490 PAX8;LOC440839 -0.42 -4.65 -0.39 8.23e-6 Lymphocyte counts; TGCT cis rs9473924 0.505 rs9296644 chr6:50828247 G/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg06238570 chr21:40685208 BRWD1 -0.79 -8.79 -0.62 1.01e-14 Cognitive function; TGCT cis rs78487399 0.808 rs77791126 chr2:43744050 G/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.02 -0.41 1.75e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs796364 0.806 rs6435040 chr2:200861161 T/G cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT cis rs1887596 0.705 rs9553869 chr13:27162757 C/G cg01312412 chr13:27282625 NA 0.3 5.28 0.43 5.64e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs17376456 0.569 rs2924374 chr5:93151141 T/C cg25358565 chr5:93447407 FAM172A -0.75 -6.28 -0.49 5.26e-9 Diabetic retinopathy; TGCT cis rs7647973 1.000 rs1982861 chr3:49577665 A/G cg07636037 chr3:49044803 WDR6 0.65 5.35 0.43 4.01e-7 Menarche (age at onset); TGCT cis rs6750047 0.515 rs13417487 chr2:38289162 G/T cg07380506 chr2:38303506 CYP1B1 0.68 6.25 0.49 6.06e-9 Cutaneous malignant melanoma;Melanoma; TGCT cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg11890956 chr21:40555474 PSMG1 1.11 12.43 0.74 1.56e-23 Cognitive function; TGCT cis rs5750830 0.649 rs5757659 chr22:39812409 A/C cg24399712 chr22:39784796 NA -1.03 -11.82 -0.73 4.77e-22 Intelligence (multi-trait analysis); TGCT cis rs2549003 1.000 rs9282763 chr5:131822133 T/C cg02551604 chr5:131831745 NA -0.9 -12.1 -0.74 9.75e-23 Asthma (sex interaction); TGCT cis rs7822232 0.908 rs56138570 chr8:145142206 G/A cg06239191 chr8:145163136 KIAA1875 -0.88 -6.45 -0.5 2.26e-9 Blood metabolite levels; TGCT cis rs3087591 0.960 rs12940303 chr17:29604862 C/T cg24425628 chr17:29625626 OMG;NF1 0.47 7.39 0.55 1.94e-11 Hip circumference; TGCT cis rs7412746 0.658 rs6656535 chr1:150940357 G/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.54 0.38 1.3e-5 Melanoma; TGCT cis rs7809950 0.678 rs75617662 chr7:107030439 G/A cg23024343 chr7:107201750 COG5 -0.46 -6.18 -0.49 8.6e-9 Coronary artery disease; TGCT trans rs6089829 0.925 rs2277767 chr20:61666937 G/A cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7703051 0.520 rs13354746 chr5:74619132 C/T cg07671805 chr5:74907694 NA 0.52 4.64 0.38 8.58e-6 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs185694 1.000 rs672233 chr13:30899601 G/A cg07600127 chr13:30881527 KATNAL1 -0.81 -6.53 -0.51 1.53e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs2836950 0.527 rs2836948 chr21:40599677 T/C cg11890956 chr21:40555474 PSMG1 -0.7 -6.87 -0.52 2.79e-10 Menarche (age at onset); TGCT cis rs1008375 0.900 rs4698622 chr4:17589557 C/T cg16339924 chr4:17578868 LAP3 0.84 7.12 0.54 7.64e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2228479 0.867 rs62052185 chr16:89969254 C/T cg06558623 chr16:89946397 TCF25 0.53 6.65 0.51 8.52e-10 Skin colour saturation; TGCT cis rs6545883 0.540 rs11687956 chr2:61851342 T/C cg15711740 chr2:61764176 XPO1 0.55 4.9 0.4 2.99e-6 Tuberculosis; TGCT cis rs769267 0.965 rs13964 chr19:19468710 C/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.73 -6.5 -0.5 1.8e-9 Tonsillectomy; TGCT cis rs5769765 0.862 rs9616774 chr22:50290599 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs9653442 0.593 rs2309811 chr2:100862359 A/G cg22139774 chr2:100720529 AFF3 -0.39 -6.48 -0.5 1.97e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7647973 0.626 rs7649428 chr3:49868876 A/T cg03034192 chr3:50606346 HEMK1;C3orf18 -0.35 -4.67 -0.39 7.84e-6 Menarche (age at onset); TGCT cis rs77741769 0.529 rs1467283 chr12:121210220 G/C cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.54e-5 Mean corpuscular volume; TGCT cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg03517284 chr6:25882590 NA -0.65 -5.81 -0.46 4.87e-8 Intelligence (multi-trait analysis); TGCT cis rs7246967 0.611 rs73030511 chr19:22826034 T/C cg05241461 chr19:22816980 ZNF492 0.67 4.51 0.38 1.47e-5 Bronchopulmonary dysplasia; TGCT cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.609 rs13082208 chr3:52781539 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.88 -0.4 3.14e-6 Bipolar disorder; TGCT cis rs10782582 0.593 rs17585530 chr1:76134990 G/A cg22875332 chr1:76189707 ACADM -0.55 -6.27 -0.49 5.53e-9 Daytime sleep phenotypes; TGCT cis rs2334880 0.836 rs9939458 chr16:71667131 T/G cg06353428 chr16:71660113 MARVELD3 1.54 12.33 0.74 2.73e-23 Malaria; TGCT cis rs526231 0.726 rs2288789 chr5:102600524 G/A cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs910316 1.000 rs4903281 chr14:75554361 G/C cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs1577917 1.000 rs9647603 chr6:86639341 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg02953382 chr22:24373134 LOC391322 -0.75 -7.83 -0.58 1.87e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs595982 0.661 rs606400 chr19:49371498 T/C cg15549821 chr19:49342101 PLEKHA4 -0.37 -5.03 -0.41 1.65e-6 Red cell distribution width; TGCT cis rs7726839 0.540 rs3762951 chr5:662613 C/G cg20362242 chr5:692897 TPPP 0.5 4.6 0.38 1.01e-5 Obesity-related traits; TGCT cis rs10892173 0.765 rs1892903 chr11:117669619 A/G cg21640587 chr11:117668038 DSCAML1 0.41 4.59 0.38 1.09e-5 Myopia; TGCT cis rs2795502 0.882 rs2744095 chr10:43337949 A/T cg20628663 chr10:43360327 NA -0.44 -6.37 -0.5 3.4e-9 Blood protein levels; TGCT cis rs875971 1.000 rs709597 chr7:65825983 A/G cg18876405 chr7:65276391 NA -0.31 -4.81 -0.4 4.3e-6 Aortic root size; TGCT cis rs9993613 0.841 rs1401139 chr4:73477532 T/C cg15102770 chr4:73434591 ADAMTS3 -0.54 -4.96 -0.41 2.26e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs6921919 0.609 rs9468365 chr6:28357966 A/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.32 -0.43 4.76e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2289681 0.525 rs12451394 chr17:42979592 G/A cg15193461 chr17:42977049 CCDC103;EFTUD2 -0.67 -5.41 -0.44 3.13e-7 Cognitive function; TGCT cis rs910316 1.000 rs10138183 chr14:75615227 T/C cg23033748 chr14:75592666 NEK9 0.27 4.6 0.38 1.05e-5 Height; TGCT cis rs860554 0.660 rs832167 chr1:201255782 T/C cg01022117 chr1:201258280 PKP1 0.33 4.81 0.4 4.29e-6 Panic disorder; TGCT cis rs7412746 0.634 rs2124952 chr1:150923774 T/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs12532878 0.652 rs62482223 chr7:100198878 C/A cg19543017 chr7:100164136 AGFG2 -0.33 -4.78 -0.39 4.81e-6 Mean corpuscular hemoglobin; TGCT cis rs6589563 0.737 rs61905088 chr11:116619867 C/A cg01124546 chr11:117515332 DSCAML1 -0.44 -4.73 -0.39 5.91e-6 Eosinophil counts; TGCT cis rs2456568 0.900 rs2000960 chr11:93682348 C/T cg17595323 chr11:93583763 C11orf90 -0.46 -6.01 -0.47 1.92e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs61990749 0.597 rs8016416 chr14:78213100 T/A cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs9916302 0.706 rs12947506 chr17:37707592 A/G cg07936489 chr17:37558343 FBXL20 -0.85 -6.18 -0.49 8.27e-9 Glomerular filtration rate (creatinine); TGCT cis rs11030122 0.632 rs714380 chr11:4059653 A/T cg18678763 chr11:4115507 RRM1 -0.48 -5.96 -0.47 2.47e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs79387448 0.626 rs80256362 chr2:103025501 A/G cg09003973 chr2:102972529 NA 1.3 8.79 0.62 1.02e-14 Gut microbiota (bacterial taxa); TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg11905131 chr22:24372483 LOC391322 0.95 11.1 0.71 2.66e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9611519 0.580 rs7286603 chr22:41440061 T/C cg03806693 chr22:41940476 POLR3H -0.59 -5.42 -0.44 2.97e-7 Neuroticism; TGCT cis rs6882046 0.513 rs254780 chr5:88019747 G/C cg24804195 chr5:87968844 LOC645323 -0.57 -5.57 -0.45 1.5e-7 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs5769765 1.000 rs764813 chr22:50286172 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs832540 0.656 rs832567 chr5:56152416 C/A cg12311346 chr5:56204834 C5orf35 -0.49 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs79387448 0.745 rs76746266 chr2:103124920 C/T cg09003973 chr2:102972529 NA 0.87 5.8 0.46 5.22e-8 Gut microbiota (bacterial taxa); TGCT cis rs9527 0.545 rs12784384 chr10:104957594 G/C cg15744005 chr10:104629667 AS3MT -0.41 -4.78 -0.39 4.88e-6 Arsenic metabolism; TGCT cis rs595982 0.559 rs17206700 chr19:49361255 A/G cg21252483 chr19:49399788 TULP2 -0.41 -6.26 -0.49 5.75e-9 Red cell distribution width; TGCT cis rs1971762 0.583 rs3844370 chr12:54086137 G/C cg16917193 chr12:54089295 NA 1.36 18.3 0.85 4.98e-37 Height; TGCT cis rs10782582 0.593 rs17848068 chr1:76190216 G/A cg10523679 chr1:76189770 ACADM -0.65 -6.74 -0.52 5.35e-10 Daytime sleep phenotypes; TGCT trans rs10504390 0.585 rs79812520 chr8:66507615 T/C cg15922513 chr12:131561251 GPR133 -0.69 -6.97 -0.53 1.66e-10 IgG glycosylation; TGCT cis rs7010267 0.935 rs11573829 chr8:119959623 T/C cg17171407 chr8:119960777 TNFRSF11B 0.33 6.18 0.49 8.29e-9 Total body bone mineral density (age 45-60); TGCT cis rs7044106 0.791 rs2416799 chr9:123480866 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 7.05 0.53 1.11e-10 Hip circumference adjusted for BMI; TGCT cis rs6570726 0.818 rs9399555 chr6:145877554 T/C cg23711669 chr6:146136114 FBXO30 0.84 8.77 0.62 1.14e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs77669868 0.568 rs3825045 chr11:114073200 C/T cg01914181 chr11:114070210 ZBTB16 0.31 4.65 0.39 8.38e-6 Monocyte percentage of white cells; TGCT cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg24549020 chr5:56110836 MAP3K1 0.7 6.0 0.47 2.02e-8 Initial pursuit acceleration; TGCT cis rs4730430 0.538 rs4455768 chr7:110134590 A/G cg14239618 chr7:110281356 NA -0.25 -4.81 -0.4 4.27e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12142240 0.738 rs17361749 chr1:46806480 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.78 -0.39 4.78e-6 Menopause (age at onset); TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg26354017 chr1:205819088 PM20D1 0.68 9.29 0.64 6.61e-16 Menarche (age at onset); TGCT cis rs6964587 1.000 rs2097739 chr7:91711466 C/T cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs116095464 0.558 rs7714335 chr5:263513 T/C cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs736408 0.812 rs2071508 chr3:52826846 A/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.52 -4.81 -0.4 4.32e-6 Bipolar disorder; TGCT cis rs2235642 0.787 rs2235646 chr16:1601287 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.32 -5.72 -0.46 7.62e-8 Coronary artery disease; TGCT cis rs597539 0.652 rs1249474 chr11:68654774 C/T cg04772025 chr11:68637568 NA 0.6 6.75 0.52 5.19e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6570726 0.935 rs367612 chr6:145828987 A/G cg23711669 chr6:146136114 FBXO30 0.69 6.22 0.49 6.89e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7937682 0.737 rs679032 chr11:111423286 G/T cg09085632 chr11:111637200 PPP2R1B -0.8 -8.33 -0.6 1.3e-13 Primary sclerosing cholangitis; TGCT cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.44 0.65 2.89e-16 Platelet count; TGCT cis rs986417 0.748 rs10145546 chr14:61100892 A/G cg27398547 chr14:60952738 C14orf39 1.44 10.1 0.67 7.17e-18 Gut microbiota (bacterial taxa); TGCT cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT trans rs1005277 0.579 rs1780130 chr10:38485378 T/A cg27523141 chr10:43048294 ZNF37B 0.72 8.28 0.6 1.71e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2820315 1.000 rs2644119 chr1:201807776 C/T cg12730843 chr1:201915899 LMOD1 -0.26 -4.73 -0.39 6.01e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs4499344 0.556 rs438268 chr19:33109904 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.76 7.52 0.56 9.54e-12 Mean platelet volume; TGCT cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg18765753 chr7:1198926 ZFAND2A -0.49 -5.89 -0.47 3.41e-8 Longevity;Endometriosis; TGCT cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg20302342 chr1:156215951 PAQR6 0.36 5.36 0.43 3.93e-7 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs12908161 0.959 rs17534709 chr15:85314397 G/C cg17173187 chr15:85201210 NMB 0.58 6.44 0.5 2.43e-9 Schizophrenia; TGCT cis rs2404602 0.583 rs11072580 chr15:76540231 G/A cg22467129 chr15:76604101 ETFA -0.65 -8.63 -0.61 2.44e-14 Blood metabolite levels; TGCT cis rs4654899 0.865 rs61779073 chr1:21398740 C/A cg01072550 chr1:21505969 NA -0.46 -6.9 -0.53 2.33e-10 Superior frontal gyrus grey matter volume; TGCT cis rs16866061 0.515 rs3738951 chr2:225368321 A/G cg12698349 chr2:225449008 CUL3 1.12 15.51 0.81 8.08e-31 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs1107366 0.637 rs2044575 chr3:125976368 A/C cg01346077 chr3:125931526 NA 0.29 4.84 0.4 3.8e-6 Metabolite levels; TGCT cis rs1903068 0.853 rs12505096 chr4:56006102 C/A cg01777861 chr4:56023843 NA 0.55 6.17 0.48 8.84e-9 Endometriosis; TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs17539620 0.624 rs111484697 chr6:154838903 A/G cg20019720 chr6:154832845 CNKSR3 0.57 4.9 0.4 2.89e-6 Lipoprotein (a) levels; TGCT cis rs4722585 0.533 rs2237335 chr7:26200213 A/G cg07876897 chr7:26191696 NFE2L3 0.39 5.25 0.43 6.49e-7 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs68170813 0.559 rs77185844 chr7:106812916 A/C cg02696742 chr7:106810147 HBP1 -0.7 -6.06 -0.48 1.52e-8 Coronary artery disease; TGCT cis rs2836974 1.000 rs12710454 chr21:40656919 A/G cg11644478 chr21:40555479 PSMG1 0.98 10.36 0.68 1.68e-18 Cognitive function; TGCT cis rs59698941 0.527 rs1032764 chr5:132185419 A/C cg27099455 chr5:132201840 GDF9;UQCRQ 0.29 4.95 0.41 2.35e-6 Apolipoprotein A-IV levels; TGCT cis rs6882076 1.000 rs4704727 chr5:156380067 T/G cg12943317 chr5:156479607 HAVCR1 -0.3 -5.31 -0.43 4.79e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg11644478 chr21:40555479 PSMG1 0.99 10.5 0.69 7.73e-19 Cognitive function; TGCT cis rs7666738 0.830 rs1967979 chr4:98966201 G/T cg17366294 chr4:99064904 C4orf37 0.74 7.54 0.56 8.74e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10197940 0.624 rs17270233 chr2:152372420 A/G cg06191203 chr2:152266755 RIF1 -0.76 -7.11 -0.54 8.05e-11 Lung cancer; TGCT cis rs7267979 0.549 rs6138536 chr20:25182648 A/G cg03522245 chr20:25566470 NINL 0.52 5.55 0.45 1.67e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2228479 0.850 rs11645916 chr16:89835234 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs11718455 0.960 rs11917885 chr3:44008013 A/G cg08738300 chr3:44038990 NA -0.85 -6.44 -0.5 2.36e-9 Coronary artery disease; TGCT cis rs9549367 0.789 rs7994324 chr13:113906497 T/C cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs2243480 1.000 rs58062456 chr7:65394852 G/T cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs595982 0.559 rs73061632 chr19:49361663 G/A cg17863274 chr19:49399704 TULP2 -0.48 -6.89 -0.53 2.45e-10 Red cell distribution width; TGCT cis rs79149102 0.579 rs8034149 chr15:75311842 G/C cg09165964 chr15:75287851 SCAMP5 -1.06 -5.78 -0.46 5.75e-8 Lung cancer; TGCT cis rs1018836 0.608 rs2142147 chr8:91468200 A/G cg16814680 chr8:91681699 NA -0.71 -7.27 -0.55 3.49e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7666738 0.753 rs34164013 chr4:98976333 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs114751999 chr4:119759651 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2982552 0.873 rs1856057 chr6:152067869 C/T cg22157087 chr6:152012887 ESR1 -0.2 -4.65 -0.39 8.39e-6 Bone properties (heel); TGCT cis rs4595586 0.545 rs7970307 chr12:39380760 A/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs986417 0.748 rs10142401 chr14:61039403 A/G cg27398547 chr14:60952738 C14orf39 1.42 10.64 0.69 3.42e-19 Gut microbiota (bacterial taxa); TGCT cis rs6903823 0.508 rs1150724 chr6:28250236 C/T cg18815343 chr6:28367644 ZSCAN12 -0.45 -4.68 -0.39 7.48e-6 Pulmonary function; TGCT cis rs9322193 0.923 rs10872649 chr6:150080590 T/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs11626933 0.885 rs6575125 chr14:90802463 C/T cg14092571 chr14:90743983 NA -0.28 -5.73 -0.46 7.34e-8 Gut microbiota (bacterial taxa); TGCT cis rs861020 0.606 rs689210 chr1:210013723 A/C cg05527609 chr1:210001259 C1orf107 0.89 8.36 0.6 1.08e-13 Orofacial clefts; TGCT cis rs6964587 0.626 rs10234074 chr7:91520119 C/T cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs910316 0.763 rs175057 chr14:75489632 C/T cg08847533 chr14:75593920 NEK9 -0.83 -8.87 -0.62 6.72e-15 Height; TGCT cis rs2204008 0.688 rs12824232 chr12:38175901 G/A cg13010199 chr12:38710504 ALG10B 0.64 5.16 0.42 9.41e-7 Bladder cancer; TGCT cis rs7618915 0.501 rs3733039 chr3:52719088 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.08e-8 Bipolar disorder; TGCT cis rs28595532 0.920 rs114611353 chr4:119736607 C/T cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs2070488 0.766 rs4679050 chr3:38482007 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.96 0.58 9.56e-13 Electrocardiographic conduction measures; TGCT cis rs595982 0.517 rs10404905 chr19:49406175 A/T cg17863274 chr19:49399704 TULP2 0.28 4.47 0.37 1.76e-5 Red cell distribution width; TGCT cis rs7615952 0.733 rs13314847 chr3:125644788 C/T cg05084668 chr3:125655381 ALG1L -0.75 -6.07 -0.48 1.41e-8 Blood pressure (smoking interaction); TGCT cis rs1990950 0.654 rs10055004 chr5:156859525 T/C cg25387487 chr5:157003181 ADAM19 0.29 4.53 0.38 1.37e-5 Lung function (FEV1/FVC); TGCT cis rs5750830 0.649 rs5750815 chr22:39798449 T/C cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs933688 0.938 rs10942634 chr5:90658392 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.92 8.52 0.61 4.52e-14 Smoking behavior; TGCT cis rs17376456 0.877 rs13170509 chr5:93378564 T/C cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs57994353 0.897 rs3812595 chr9:139369062 C/T cg13741927 chr9:139327495 INPP5E -0.25 -5.59 -0.45 1.38e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs78707713 0.560 rs55668536 chr10:71242655 A/G cg12610070 chr10:71211762 TSPAN15 -0.62 -7.37 -0.55 2.12e-11 Venous thromboembolism; TGCT cis rs9913156 0.707 rs72835625 chr17:4560274 G/A cg19197139 chr17:4613644 ARRB2 0.86 7.9 0.58 1.32e-12 Lymphocyte counts; TGCT cis rs1775715 0.737 rs2778672 chr10:32122419 T/C cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.38e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6088590 0.561 rs6059932 chr20:33175466 C/T cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs7666738 0.800 rs10008654 chr4:98820498 C/A cg18180107 chr4:99064573 C4orf37 0.55 5.25 0.43 6.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg23131131 chr22:24373011 LOC391322 -0.77 -8.41 -0.6 8.36e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs501916 0.796 rs75186419 chr15:48043934 G/A cg16110827 chr15:48056943 SEMA6D -0.17 -4.84 -0.4 3.74e-6 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs6912958 0.781 rs2273129 chr6:88182439 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.54 -5.23 -0.43 7.03e-7 Monocyte percentage of white cells; TGCT cis rs17122693 1.000 rs1494176 chr14:51083372 A/C cg04730355 chr14:51134070 SAV1 1.19 8.84 0.62 8.09e-15 Cognitive performance; TGCT cis rs36051895 0.623 rs72703608 chr9:5258127 A/G cg02405213 chr9:5042618 JAK2 -0.69 -8.19 -0.59 2.68e-13 Pediatric autoimmune diseases; TGCT cis rs7666738 0.822 rs11097599 chr4:98959562 T/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2302464 1.000 rs6844968 chr4:15727264 G/T cg18497811 chr4:14860861 NA -0.48 -4.47 -0.37 1.76e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs4711350 0.765 rs756138 chr6:33755711 G/C cg13859433 chr6:33739653 LEMD2 -0.33 -4.93 -0.4 2.6e-6 Schizophrenia; TGCT cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg26338869 chr17:61819248 STRADA 0.58 5.15 0.42 9.97e-7 Prudent dietary pattern; TGCT cis rs2204008 0.807 rs4123933 chr12:37973539 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs3749237 0.636 rs1568662 chr3:49521263 A/G cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.19 -0.42 8.22e-7 Coronary artery disease; TGCT cis rs4629710 0.592 rs3777476 chr6:131533821 A/C cg12606694 chr6:131520996 AKAP7 0.39 4.62 0.38 9.58e-6 Multiple myeloma (IgH translocation); TGCT cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg17554472 chr22:41940697 POLR3H -0.47 -4.79 -0.4 4.68e-6 Vitiligo; TGCT cis rs10791097 0.694 rs7940027 chr11:130745591 A/G cg12179176 chr11:130786555 SNX19 0.84 10.15 0.67 5.61e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9549260 0.755 rs2721066 chr13:41156188 C/T cg21288729 chr13:41239152 FOXO1 -0.98 -10.31 -0.68 2.2e-18 Red blood cell count; TGCT cis rs912057 1.000 rs1294414 chr6:6740366 A/G cg06612196 chr6:6737390 NA 0.39 4.99 0.41 2.02e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg10047753 chr17:41438598 NA 0.91 8.44 0.6 6.86e-14 Menopause (age at onset); TGCT cis rs9308731 1.000 rs2241843 chr2:111879381 C/A cg04202892 chr2:111875749 ACOXL 0.43 4.69 0.39 7.05e-6 Chronic lymphocytic leukemia; TGCT cis rs11252926 0.537 rs61836851 chr10:447231 T/C cg20256804 chr10:444983 DIP2C -0.21 -4.51 -0.38 1.5e-5 Psychosis in Alzheimer's disease; TGCT cis rs13191362 0.935 rs13219926 chr6:163004213 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9611565 0.592 rs4822040 chr22:41963553 C/G cg06634786 chr22:41940651 POLR3H -0.83 -7.84 -0.58 1.8e-12 Vitiligo; TGCT cis rs7833790 1.000 rs7833384 chr8:82730915 T/C cg27398817 chr8:82754497 SNX16 -0.84 -6.34 -0.49 3.89e-9 Diastolic blood pressure; TGCT cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg21672276 chr3:44754072 ZNF502 -0.52 -5.75 -0.46 6.58e-8 Depressive symptoms; TGCT cis rs6540559 0.546 rs74991018 chr1:210033790 T/G cg21951975 chr1:209979733 IRF6 0.69 5.18 0.42 8.74e-7 Cleft lip with or without cleft palate; TGCT cis rs58688157 0.960 rs1051390 chr11:613165 G/C cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs4689592 0.622 rs2276968 chr4:7070118 T/G cg25660036 chr4:7070649 GRPEL1 -0.63 -5.39 -0.44 3.41e-7 Monocyte percentage of white cells; TGCT cis rs9926296 0.643 rs2159114 chr16:89831841 A/G cg03388025 chr16:89894329 SPIRE2 0.31 4.61 0.38 9.86e-6 Vitiligo; TGCT cis rs11098499 0.908 rs12504149 chr4:120318577 G/A cg09307838 chr4:120376055 NA 0.65 6.17 0.48 8.93e-9 Corneal astigmatism; TGCT cis rs7226408 0.842 rs56178761 chr18:34331755 G/A cg06757138 chr18:34340585 FHOD3 0.29 4.95 0.41 2.4e-6 Obesity-related traits; TGCT cis rs10114408 0.918 rs4460439 chr9:96650564 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs3820068 0.705 rs4646063 chr1:15829813 G/A cg05660106 chr1:15850417 CASP9 1.15 12.8 0.75 1.94e-24 Systolic blood pressure; TGCT cis rs28456 1 rs28456 chr11:61589481 A/G cg19610905 chr11:61596333 FADS2 -1.05 -11.51 -0.72 2.6e-21 Bipolar disorder; TGCT cis rs12477438 0.765 rs62154638 chr2:99639584 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs1048466 0.744 rs11062945 chr12:540544 C/G cg26458557 chr12:285704 IQSEC3 0.26 4.55 0.38 1.24e-5 Obesity (early onset extreme); TGCT cis rs6964587 1.000 rs2299238 chr7:91654517 G/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs2456568 0.778 rs2456563 chr11:93678675 C/T cg16099599 chr11:93583650 C11orf90 -0.37 -4.58 -0.38 1.13e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1018836 0.632 rs6995399 chr8:91481629 T/C cg16814680 chr8:91681699 NA -0.77 -7.99 -0.58 7.8e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs11864453 0.647 rs10492814 chr16:72126514 G/A cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs7678296 0.649 rs73128366 chr4:37241908 T/C cg18431856 chr4:37245254 KIAA1239 0.69 4.52 0.38 1.45e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg15687855 chr3:44754131 ZNF502 -0.49 -5.97 -0.47 2.36e-8 Depressive symptoms; TGCT cis rs8064299 0.967 rs3744208 chr17:72767565 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.78 7.92 0.58 1.17e-12 Monocyte count; TGCT cis rs7703051 0.513 rs6895057 chr5:74624234 G/A cg00601450 chr5:74908170 NA -0.43 -4.52 -0.38 1.41e-5 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.92 7.41 0.55 1.73e-11 Platelet count; TGCT cis rs61884328 0.733 rs61897852 chr11:47203155 G/A cg13308137 chr11:47528955 CUGBP1 0.38 4.48 0.37 1.65e-5 Total body bone mineral density (age over 60); TGCT cis rs72634258 0.503 rs34177663 chr1:7833228 A/G cg26816564 chr1:7831052 VAMP3 0.95 6.88 0.53 2.56e-10 Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg20007245 chr22:24372913 LOC391322 -0.71 -7.04 -0.53 1.16e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7267979 1.000 rs2258201 chr20:25272490 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs858239 0.600 rs7787110 chr7:23138474 C/T cg05602783 chr7:23145260 KLHL7 -0.66 -5.8 -0.46 5.24e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs8180040 0.620 rs11720139 chr3:47036756 C/G cg27129171 chr3:47204927 SETD2 -0.7 -8.27 -0.6 1.75e-13 Colorectal cancer; TGCT cis rs13118159 0.550 rs11941200 chr4:1369093 C/G cg20887711 chr4:1340912 KIAA1530 0.92 8.12 0.59 3.93e-13 Longevity; TGCT cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs2721195 0.654 rs4610795 chr8:145881333 C/T cg12270520 chr8:146023939 ZNF517 -0.6 -5.29 -0.43 5.35e-7 Age at first birth; TGCT cis rs9796 0.689 rs6492983 chr15:41436049 T/G cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.84 -0.52 3.18e-10 Menopause (age at onset); TGCT cis rs2236918 0.710 rs1626057 chr1:242038136 G/C cg04158730 chr1:242011433 EXO1 0.56 5.16 0.42 9.57e-7 Menopause (age at onset); TGCT cis rs67478160 0.619 rs10083367 chr14:104314183 C/G cg26031613 chr14:104095156 KLC1 0.69 6.98 0.53 1.59e-10 Schizophrenia; TGCT cis rs8062405 0.540 rs193628 chr16:28582142 G/T cg00931491 chr16:28608288 SULT1A2 0.3 4.44 0.37 1.94e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7659604 0.676 rs6855269 chr4:122697418 T/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.55 -0.45 1.69e-7 Type 2 diabetes; TGCT cis rs6540559 0.611 rs17015226 chr1:209970096 C/G cg21951975 chr1:209979733 IRF6 0.72 5.64 0.45 1.08e-7 Cleft lip with or without cleft palate; TGCT cis rs826838 0.935 rs11168761 chr12:38997211 C/A cg13010199 chr12:38710504 ALG10B 0.82 7.07 0.54 1.01e-10 Heart rate; TGCT cis rs6589563 0.737 rs11825181 chr11:116626258 G/A cg01124546 chr11:117515332 DSCAML1 -0.44 -4.77 -0.39 5.18e-6 Eosinophil counts; TGCT cis rs7216064 0.953 rs10445361 chr17:65962238 G/T cg12091567 chr17:66097778 LOC651250 0.77 6.37 0.5 3.38e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs59197085 0.551 rs3807309 chr7:128472138 G/A cg00260937 chr7:128520193 KCP 0.49 4.87 0.4 3.33e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs7666738 0.791 rs1896156 chr4:99020882 C/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs912057 0.632 rs1294432 chr6:6745027 C/T cg06612196 chr6:6737390 NA 0.47 6.77 0.52 4.57e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs4665809 1.000 rs3910272 chr2:26287842 T/A cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs7769051 1.000 rs6934161 chr6:133124077 C/T cg07930552 chr6:133119739 C6orf192 -0.96 -5.41 -0.44 3.07e-7 Type 2 diabetes nephropathy; TGCT cis rs2243480 1.000 rs10247526 chr7:65780696 T/G cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs6582630 0.679 rs10785514 chr12:38573689 T/C cg26384229 chr12:38710491 ALG10B 0.55 5.04 0.41 1.58e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs763014 0.898 rs8050792 chr16:656033 T/C cg09263875 chr16:632152 PIGQ 0.31 6.76 0.52 4.93e-10 Height; TGCT cis rs36051895 0.632 rs10118930 chr9:5148278 C/T cg02405213 chr9:5042618 JAK2 -0.72 -9.74 -0.66 5.3e-17 Pediatric autoimmune diseases; TGCT cis rs1008375 0.797 rs6843530 chr4:17593605 G/T cg18681998 chr4:17616180 MED28 1.0 10.01 0.67 1.2e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1371867 0.555 rs2861348 chr8:101285074 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.42 -0.5 2.67e-9 Atrioventricular conduction; TGCT cis rs9926296 0.527 rs1800335 chr16:89846195 A/G cg03388025 chr16:89894329 SPIRE2 0.53 9.63 0.65 9.95e-17 Vitiligo; TGCT cis rs8031584 0.707 rs4556757 chr15:31188179 C/T cg08109568 chr15:31115862 NA -0.35 -4.79 -0.4 4.66e-6 Huntington's disease progression; TGCT cis rs6977660 0.714 rs17141884 chr7:19790280 A/G cg05791153 chr7:19748676 TWISTNB -0.84 -5.11 -0.42 1.17e-6 Thyroid stimulating hormone; TGCT cis rs7655441 1.000 rs10000339 chr4:80878580 C/T cg02241357 chr4:80885279 ANTXR2 -0.23 -4.46 -0.37 1.81e-5 Neutrophil percentage of white cells; TGCT cis rs7666738 0.822 rs13110418 chr4:99046963 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT trans rs916888 0.773 rs199443 chr17:44819565 C/T cg01341218 chr17:43662625 NA 1.11 9.15 0.63 1.43e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs35851103 0.627 rs6601644 chr8:11847078 G/A cg06636001 chr8:8085503 FLJ10661 0.78 7.37 0.55 2.11e-11 Neuroticism; TGCT cis rs34526934 0.566 rs34028621 chr2:177042779 C/T cg14324370 chr2:177042789 NA -0.91 -8.69 -0.62 1.8e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs6912958 0.559 rs173333 chr6:88047754 T/G cg12350822 chr6:88032061 C6orf162;GJB7 0.47 6.29 0.49 5.04e-9 Monocyte percentage of white cells; TGCT cis rs4951018 0.853 rs1573104 chr1:205636907 A/C cg07167872 chr1:205819463 PM20D1 -0.37 -4.47 -0.37 1.74e-5 Prostate-specific antigen levels; TGCT cis rs78707713 0.511 rs28697194 chr10:71215483 T/C cg12610070 chr10:71211762 TSPAN15 -0.62 -7.12 -0.54 7.54e-11 Venous thromboembolism; TGCT cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs7523273 0.606 rs859706 chr1:207962270 G/A cg22525895 chr1:207977042 MIR29B2 -0.53 -8.99 -0.63 3.49e-15 Schizophrenia; TGCT cis rs9341808 0.667 rs2490244 chr6:80891112 A/T cg08355045 chr6:80787529 NA 0.31 5.1 0.42 1.26e-6 Sitting height ratio; TGCT cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg02353165 chr6:42928485 GNMT -0.97 -9.95 -0.67 1.66e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9894429 1.000 rs9894429 chr17:79596811 C/T cg21028142 chr17:79581711 NPLOC4 0.29 6.86 0.52 2.94e-10 Eye color traits; TGCT cis rs9868809 0.772 rs9821797 chr3:48718253 T/A cg00383909 chr3:49044727 WDR6 0.96 5.85 0.47 4.04e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9611565 0.506 rs2024566 chr22:41697338 A/G cg13695892 chr22:41940480 POLR3H -0.67 -6.2 -0.49 7.58e-9 Vitiligo; TGCT cis rs35306767 0.761 rs11253560 chr10:1047226 T/G cg20503657 chr10:835505 NA 0.61 6.71 0.52 6.11e-10 Eosinophil percentage of granulocytes; TGCT cis rs763014 0.931 rs2071982 chr16:630405 T/G cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs11711311 0.955 rs9830102 chr3:113408302 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.8 -7.16 -0.54 6.37e-11 IgG glycosylation; TGCT cis rs1008375 0.900 rs13101742 chr4:17701297 G/A cg10189774 chr4:17578691 LAP3 -0.58 -4.96 -0.41 2.29e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1008375 0.900 rs4698625 chr4:17599500 G/T cg18681998 chr4:17616180 MED28 0.87 7.67 0.57 4.29e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs250677 0.687 rs250667 chr5:148455134 A/G cg18129178 chr5:148520854 ABLIM3 0.47 6.49 0.5 1.87e-9 Breast cancer; TGCT cis rs926938 0.583 rs12401670 chr1:115244337 C/T cg12756093 chr1:115239321 AMPD1 -0.42 -5.34 -0.43 4.33e-7 Autism; TGCT cis rs1008375 0.966 rs7658240 chr4:17588950 A/G cg16339924 chr4:17578868 LAP3 -0.82 -7.21 -0.54 4.86e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9486719 0.948 rs11152952 chr6:96894303 A/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7246657 0.722 rs8103647 chr19:38100452 C/A cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.71e-6 Coronary artery calcification; TGCT cis rs2836974 0.932 rs2836955 chr21:40619887 G/A cg06238570 chr21:40685208 BRWD1 0.59 5.29 0.43 5.27e-7 Cognitive function; TGCT cis rs9814567 1.000 rs28409322 chr3:134252385 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2073300 1.000 rs59283536 chr20:23457575 A/T cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs11696501 0.739 rs6073846 chr20:44296323 G/T cg11783356 chr20:44313418 WFDC10B 0.33 4.7 0.39 6.88e-6 Brain structure; TGCT trans rs1814175 0.645 rs866427 chr11:49923853 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs11098499 0.909 rs71614422 chr4:120359340 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs769267 0.965 rs6511026 chr19:19391402 C/T cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs2455799 0.586 rs1900613 chr3:15903638 G/A cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs806795 0.605 rs6935954 chr6:26255451 A/G cg00631329 chr6:26305371 NA -0.33 -5.13 -0.42 1.08e-6 Mosquito bite size; TGCT cis rs2982552 0.844 rs3020343 chr6:152054363 C/T cg22157087 chr6:152012887 ESR1 0.21 5.09 0.42 1.27e-6 Bone properties (heel); TGCT cis rs7010267 0.773 rs10101385 chr8:119923850 A/G cg17171407 chr8:119960777 TNFRSF11B -0.28 -4.94 -0.41 2.46e-6 Total body bone mineral density (age 45-60); TGCT cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.55 -6.35 -0.5 3.74e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs2239785 0.958 rs136162 chr22:36657474 A/G cg15716373 chr22:36655542 APOL1 -0.44 -5.07 -0.41 1.4e-6 Glomerulosclerosis; TGCT cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs11690462 0.926 rs12615704 chr2:26551903 G/C cg04726446 chr2:26624865 C2orf39 0.43 4.61 0.38 1e-5 Coronary artery disease; TGCT cis rs3617 0.573 rs62253583 chr3:52928334 G/A cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.67 0.39 7.65e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6835098 0.924 rs7672108 chr4:174165126 A/G cg08422745 chr4:174089978 GALNT7 0.85 9.14 0.63 1.49e-15 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs9911578 0.967 rs6503890 chr17:57064167 A/G cg12560992 chr17:57184187 TRIM37 0.77 9.3 0.64 6.39e-16 Intelligence (multi-trait analysis); TGCT trans rs1908814 0.516 rs10113145 chr8:11793295 A/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs7666738 0.830 rs7672720 chr4:98938760 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9388451 0.505 rs9372828 chr6:126175185 A/T cg05901451 chr6:126070800 HEY2 -0.7 -7.23 -0.54 4.3e-11 Brugada syndrome; TGCT cis rs514406 0.861 rs4926576 chr1:53226775 C/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.82 -0.62 8.9e-15 Monocyte count; TGCT cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.95 7.54 0.56 8.47e-12 Platelet count; TGCT cis rs3733585 0.699 rs1079128 chr4:9951221 T/C cg00071950 chr4:10020882 SLC2A9 -0.55 -6.43 -0.5 2.49e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12712073 0.837 rs11692867 chr2:100759477 G/A cg07810366 chr2:100720526 AFF3 -0.36 -5.22 -0.42 7.2e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs13122054 chr4:98972974 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs17331151 0.541 rs11709430 chr3:52862055 G/A cg15956490 chr3:53032818 SFMBT1 0.47 6.14 0.48 1.03e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9810089 0.934 rs696520 chr3:136056861 T/C cg12473912 chr3:136751656 NA 0.35 4.9 0.4 2.92e-6 Gestational age at birth (child effect); TGCT cis rs116095464 0.558 rs73031482 chr5:227594 G/A cg22857025 chr5:266934 NA -0.32 -6.53 -0.51 1.5e-9 Breast cancer; TGCT cis rs739496 1.000 rs739496 chr12:111887659 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs9381040 0.610 rs742495 chr6:41018233 A/G cg03526776 chr6:41159608 TREML2 0.26 5.14 0.42 1.05e-6 Alzheimer's disease (late onset); TGCT cis rs8072100 0.688 rs8079142 chr17:45442049 G/A cg08085267 chr17:45401833 C17orf57 -0.51 -5.61 -0.45 1.26e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs8077577 0.945 rs11656035 chr17:18086025 T/C cg09161412 chr17:18057145 MYO15A -0.64 -5.2 -0.42 7.92e-7 Obesity-related traits; TGCT cis rs903263 0.965 rs6695851 chr1:84654139 T/A cg09664975 chr1:84543551 PRKACB 0.47 4.48 0.37 1.65e-5 Breast cancer (male); TGCT cis rs295140 1.000 rs3739121 chr2:201171014 G/C cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs936229 0.813 rs1350193 chr15:75084281 G/C cg10253484 chr15:75165896 SCAMP2 -0.65 -5.12 -0.42 1.15e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs9311474 0.713 rs181274 chr3:52233861 T/A cg10802521 chr3:52805072 NEK4 -0.56 -6.01 -0.47 1.92e-8 Electroencephalogram traits; TGCT cis rs6088580 0.660 rs6087592 chr20:33114503 A/G cg06115741 chr20:33292138 TP53INP2 0.54 4.6 0.38 1.03e-5 Glomerular filtration rate (creatinine); TGCT cis rs394563 0.591 rs237012 chr6:149729198 T/C cg16235748 chr6:149772707 ZC3H12D -0.44 -4.92 -0.4 2.74e-6 Dupuytren's disease; TGCT cis rs2856321 1.000 rs11054423 chr12:11859731 A/G cg26373351 chr12:12031304 ETV6 0.21 4.43 0.37 2.01e-5 Height; TGCT cis rs9296092 0.538 rs62407567 chr6:33537213 A/G cg13560919 chr6:33536144 NA -0.23 -4.81 -0.4 4.34e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs13108904 0.870 rs13132584 chr4:1251504 G/T cg00684032 chr4:1343700 KIAA1530 0.22 4.82 0.4 4.11e-6 Obesity-related traits; TGCT cis rs7726839 0.540 rs72703079 chr5:595173 T/C cg16624210 chr5:671434 TPPP 0.45 4.92 0.4 2.71e-6 Obesity-related traits; TGCT cis rs7089973 0.604 rs2420066 chr10:116583897 A/G cg03647239 chr10:116582469 FAM160B1 0.58 5.63 0.45 1.16e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT trans rs3790455 0.610 rs1185700 chr1:156450719 G/A cg16443977 chr5:115884994 SEMA6A 0.39 6.66 0.51 8.1e-10 Migraine; TGCT cis rs3796352 0.892 rs3821872 chr3:53080555 C/G cg27565382 chr3:53032988 SFMBT1 -0.41 -4.63 -0.38 9.12e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4906332 1.000 rs17680085 chr14:103953154 T/C cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs7553035 1.000 rs2166104 chr1:211690818 A/T cg16589830 chr1:212284214 NA 0.51 4.68 0.39 7.31e-6 Retinopathy in non-diabetics; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.5 -4.67 -0.39 7.61e-6 Prudent dietary pattern; TGCT cis rs7772486 0.790 rs2265918 chr6:146219164 A/G cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.89e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4654899 1.000 rs4654905 chr1:21509558 A/G cg01072550 chr1:21505969 NA -0.5 -8.08 -0.59 4.94e-13 Superior frontal gyrus grey matter volume; TGCT cis rs7192750 0.527 rs30433 chr16:72145404 T/C cg06353428 chr16:71660113 MARVELD3 1.02 5.08 0.42 1.35e-6 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs4665809 1.000 rs2384323 chr2:26306473 C/T cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs6993813 0.653 rs7017881 chr8:120047857 C/T cg17171407 chr8:119960777 TNFRSF11B -0.25 -4.5 -0.37 1.53e-5 Bone mineral density (hip); TGCT cis rs7943203 0.525 rs665293 chr11:108142617 G/A cg04873221 chr11:107992290 ACAT1 -0.61 -4.96 -0.41 2.3e-6 Red blood cell count;Mean corpuscular volume; TGCT cis rs853679 0.517 rs4713141 chr6:28101678 G/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs17473412 0.963 rs79413938 chr5:122686099 T/C cg15125798 chr5:122621645 NA -0.55 -5.09 -0.42 1.28e-6 Total body bone mineral density; TGCT cis rs7714584 1.000 rs11167515 chr5:150239471 G/T cg22134413 chr5:150180641 NA 1.11 8.03 0.58 6.39e-13 Crohn's disease; TGCT cis rs6951245 0.580 rs77101766 chr7:1122438 A/G cg03188948 chr7:1209495 NA 0.51 5.31 0.43 4.84e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7843479 1.000 rs727694 chr8:21849962 T/C cg17168535 chr8:21777572 XPO7 0.64 5.78 0.46 5.66e-8 Mean corpuscular volume; TGCT cis rs3087591 1.000 rs984125 chr17:29547254 A/G cg24425628 chr17:29625626 OMG;NF1 0.46 7.32 0.55 2.77e-11 Hip circumference; TGCT cis rs4819052 0.851 rs2838850 chr21:46671445 G/C cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7674212 0.581 rs11946020 chr4:103944742 T/C cg16532752 chr4:104119610 CENPE -0.59 -5.19 -0.42 8.28e-7 Type 2 diabetes; TGCT cis rs7618915 0.547 rs2118540 chr3:52629386 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs2288884 1.000 rs2288884 chr19:52532271 C/T cg13540795 chr19:52551618 ZNF432 -0.58 -5.03 -0.41 1.67e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT trans rs17685 0.712 rs7794454 chr7:75776010 A/G cg19862616 chr7:65841803 NCRNA00174 -0.52 -9.02 -0.63 2.88e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7017914 0.870 rs2732096 chr8:71919980 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT trans rs2727020 0.734 rs1164663 chr11:49294723 A/T cg11707556 chr5:10655725 ANKRD33B 0.38 6.8 0.52 3.89e-10 Coronary artery disease; TGCT cis rs6831352 0.918 rs3919370 chr4:100064326 A/T cg12011299 chr4:100065546 ADH4 -0.42 -4.98 -0.41 2.06e-6 Alcohol dependence; TGCT cis rs2637266 0.967 rs12246436 chr10:78352914 C/T cg18941641 chr10:78392320 NA 0.42 5.2 0.42 8.09e-7 Pulmonary function; TGCT cis rs6495367 0.803 rs2870111 chr15:79403585 C/T cg17916960 chr15:79447300 NA 0.38 5.75 0.46 6.65e-8 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg05896524 chr21:47604654 C21orf56 -0.43 -4.76 -0.39 5.21e-6 Testicular germ cell tumor; TGCT cis rs2594989 0.837 rs2454497 chr3:11501597 T/C cg00170343 chr3:11313890 ATG7 0.69 5.12 0.42 1.16e-6 Circulating chemerin levels; TGCT cis rs7666738 0.680 rs34267968 chr4:99002574 A/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs62244186 0.608 rs2888390 chr3:44511405 G/A cg04389838 chr3:44770851 ZNF501 -0.38 -4.94 -0.41 2.5e-6 Depressive symptoms; TGCT cis rs617219 0.574 rs3930426 chr5:78597535 C/T cg23514016 chr5:78407564 BHMT -0.3 -4.51 -0.38 1.49e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs3734905 1.000 rs78099962 chr6:169934984 T/C cg20469989 chr6:170102314 C6orf120;WDR27 -0.87 -4.66 -0.39 8.1e-6 HIV-1 control; TGCT cis rs7572733 0.534 rs58374969 chr2:198764363 C/T cg00792783 chr2:198669748 PLCL1 0.59 5.32 0.43 4.73e-7 Dermatomyositis; TGCT cis rs2721195 0.845 rs3816732 chr8:145724275 T/C cg15857475 chr8:145742913 RECQL4;LRRC14 0.86 8.98 0.63 3.68e-15 Age at first birth; TGCT cis rs67073037 0.955 rs4666151 chr2:29177344 C/A cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg02487422 chr3:49467188 NICN1 0.5 4.75 0.39 5.41e-6 Menarche (age at onset); TGCT cis rs8072100 0.790 rs11656856 chr17:45714671 C/T cg10024583 chr17:45772800 TBKBP1 -0.45 -4.61 -0.38 9.75e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT trans rs1005277 0.579 rs1780137 chr10:38501475 C/G cg27523141 chr10:43048294 ZNF37B 0.72 8.34 0.6 1.21e-13 Extrinsic epigenetic age acceleration; TGCT cis rs208520 0.954 rs1468153 chr6:67009054 A/C cg07460842 chr6:66804631 NA 0.69 6.06 0.48 1.51e-8 Exhaled nitric oxide output; TGCT cis rs9368481 0.729 rs9379948 chr6:26944783 T/G cg02458000 chr6:26745757 NA 0.5 4.6 0.38 1.04e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9682041 0.696 rs9872796 chr3:170099393 T/G cg11886554 chr3:170076028 SKIL 0.83 6.42 0.5 2.66e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs17376456 1.000 rs58734583 chr5:93532155 C/T cg21475434 chr5:93447410 FAM172A 0.61 4.51 0.38 1.47e-5 Diabetic retinopathy; TGCT cis rs9611565 0.694 rs202641 chr22:41833116 C/T cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Vitiligo; TGCT cis rs7666738 0.791 rs1405766 chr4:98965389 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6484504 0.532 rs11031332 chr11:31278962 T/C cg26647111 chr11:31128758 NA -0.35 -4.86 -0.4 3.44e-6 Red blood cell count; TGCT cis rs1008375 0.966 rs11947836 chr4:17697187 A/G cg10189774 chr4:17578691 LAP3 -0.56 -4.65 -0.38 8.54e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6951245 1.000 rs11766526 chr7:1101433 G/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17376456 0.825 rs17314762 chr5:93231200 C/T cg21475434 chr5:93447410 FAM172A 0.7 4.86 0.4 3.51e-6 Diabetic retinopathy; TGCT cis rs77741769 0.571 rs3809313 chr12:121329967 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.56e-5 Mean corpuscular volume; TGCT cis rs3816788 0.792 rs10097055 chr8:21872328 A/G cg17168535 chr8:21777572 XPO7 0.77 7.65 0.57 4.88e-12 Lung cancer in ever smokers; TGCT cis rs9527 0.590 rs7897663 chr10:104905604 T/C cg15744005 chr10:104629667 AS3MT -0.41 -4.73 -0.39 6.06e-6 Arsenic metabolism; TGCT cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.12 14.83 0.8 3.07e-29 Height; TGCT cis rs6752107 0.840 rs2119505 chr2:234154651 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.98 0.41 2.06e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs67460515 0.892 rs2100238 chr3:161058055 T/A cg03342759 chr3:160939853 NMD3 -0.52 -5.68 -0.45 9.16e-8 Parkinson's disease; TGCT cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs11785400 0.793 rs3735993 chr8:143741170 G/A cg10596483 chr8:143751796 JRK 0.55 5.49 0.44 2.13e-7 Schizophrenia; TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs1278769 0.786 rs7998551 chr13:113540649 G/T cg11520003 chr13:113540631 ATP11A -0.31 -4.65 -0.39 8.41e-6 Interstitial lung disease; TGCT cis rs8020441 0.541 rs59857560 chr14:51158851 G/A cg04730355 chr14:51134070 SAV1 1.22 9.45 0.65 2.75e-16 Cognitive performance; TGCT cis rs4689388 0.856 rs4308430 chr4:6294095 A/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12681287 0.547 rs60982560 chr8:87515046 C/T cg27223183 chr8:87520930 FAM82B -0.96 -7.08 -0.54 9.31e-11 Caudate activity during reward; TGCT cis rs11098499 0.954 rs13145352 chr4:120409963 C/T cg09307838 chr4:120376055 NA -0.7 -6.58 -0.51 1.21e-9 Corneal astigmatism; TGCT cis rs739496 0.542 rs12423926 chr12:111781055 C/T cg10833066 chr12:111807467 FAM109A -0.45 -7.35 -0.55 2.3e-11 Platelet count; TGCT cis rs2249625 0.545 rs2496488 chr6:72875985 A/T cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs7772486 0.790 rs1854900 chr6:146331382 G/A cg23711669 chr6:146136114 FBXO30 0.87 9.48 0.65 2.27e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1997103 0.954 rs6593235 chr7:55410986 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7582180 0.764 rs12622318 chr2:100927375 T/C cg14675211 chr2:100938903 LONRF2 0.52 4.98 0.41 2.1e-6 Intelligence (multi-trait analysis); TGCT cis rs13256369 1.000 rs13267501 chr8:8574058 G/A cg18904891 chr8:8559673 CLDN23 0.64 5.89 0.47 3.36e-8 Obesity-related traits; TGCT cis rs7829975 0.681 rs2271342 chr8:8643938 C/T cg15556689 chr8:8085844 FLJ10661 0.72 6.52 0.51 1.63e-9 Mood instability; TGCT cis rs9611565 0.921 rs2235846 chr22:41741042 G/C cg17554472 chr22:41940697 POLR3H -0.4 -4.58 -0.38 1.11e-5 Vitiligo; TGCT cis rs60871478 0.636 rs12534606 chr7:895928 A/G cg00475322 chr7:917719 C7orf20 0.5 4.87 0.4 3.37e-6 Cerebrospinal P-tau181p levels; TGCT cis rs9341808 0.591 rs7741013 chr6:80916330 G/A cg08355045 chr6:80787529 NA 0.3 5.05 0.41 1.51e-6 Sitting height ratio; TGCT cis rs707040 0.921 rs7566094 chr2:155228511 T/C cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs72781680 0.715 rs72796332 chr2:24142060 G/A cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs9549367 0.713 rs510160 chr13:113822481 A/G cg00898013 chr13:113819073 PROZ 0.51 6.41 0.5 2.79e-9 Platelet distribution width; TGCT cis rs2228479 0.850 rs79244293 chr16:89896220 T/C cg06558623 chr16:89946397 TCF25 0.55 4.77 0.39 5.13e-6 Skin colour saturation; TGCT cis rs2073300 1.000 rs6137976 chr20:23463241 C/T cg09953122 chr20:23471693 CST8 -0.67 -4.62 -0.38 9.54e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs916888 0.610 rs199442 chr17:44820122 G/A cg15921436 chr17:44337874 NA 0.43 6.49 0.5 1.89e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6582630 0.537 rs2204006 chr12:38407098 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.58 0.56 6.92e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg10108389 chr3:44770937 ZNF501 -0.46 -4.63 -0.38 9.25e-6 Depressive symptoms; TGCT cis rs9910055 0.762 rs227579 chr17:42223134 A/T cg13607699 chr17:42295918 UBTF -0.83 -7.64 -0.57 5.01e-12 Total body bone mineral density; TGCT cis rs77741769 0.571 rs10849807 chr12:121314056 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg21280719 chr6:42927975 GNMT -0.37 -4.57 -0.38 1.17e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs17030434 0.954 rs17030570 chr4:154755186 A/G cg14289246 chr4:154710475 SFRP2 0.93 7.27 0.55 3.54e-11 Electrocardiographic conduction measures; TGCT cis rs11690462 0.963 rs13014464 chr2:26581018 C/T cg11525280 chr2:26624667 C2orf39 0.35 4.47 0.37 1.73e-5 Coronary artery disease; TGCT cis rs3087591 0.683 rs2854303 chr17:29716342 C/G cg24425628 chr17:29625626 OMG;NF1 0.41 6.03 0.48 1.73e-8 Hip circumference; TGCT cis rs10927875 0.830 rs1763610 chr1:16335527 C/G cg22431228 chr1:16359049 CLCNKA 0.25 4.88 0.4 3.19e-6 Dilated cardiomyopathy; TGCT cis rs9425326 0.508 rs2500106 chr1:183808474 T/G cg15569801 chr1:184197096 NA -0.14 -5.03 -0.41 1.7e-6 Antipsychotic drug-induced QTc interval change in schizophrenia; TGCT cis rs4919694 1.000 rs7099987 chr10:104807926 C/T cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT cis rs6752107 0.967 rs55835501 chr2:234157733 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 5.0 0.41 1.87e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1008375 0.932 rs13134570 chr4:17692863 C/T cg10189774 chr4:17578691 LAP3 -0.55 -4.64 -0.38 8.7e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4808199 0.948 rs2023883 chr19:19405480 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.19 0.42 8.51e-7 Nonalcoholic fatty liver disease; TGCT cis rs3829109 0.564 rs11145891 chr9:139293912 T/C cg13741927 chr9:139327495 INPP5E -0.24 -5.18 -0.42 8.84e-7 Peak insulin response;Acute insulin response; TGCT cis rs4746818 1.000 rs10762259 chr10:70890929 C/T cg04149295 chr10:70884716 VPS26A 0.79 5.4 0.44 3.22e-7 Left atrial antero-posterior diameter; TGCT cis rs10032931 0.743 rs1385668 chr4:96459330 A/G cg17031751 chr4:96469067 UNC5C -0.41 -5.08 -0.42 1.35e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs2070488 1.000 rs13074025 chr3:38455704 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 9.06e-17 Electrocardiographic conduction measures; TGCT cis rs7584330 0.784 rs6724766 chr2:238413600 A/G cg14458575 chr2:238380390 NA 0.44 6.59 0.51 1.11e-9 Prostate cancer; TGCT cis rs3733585 0.699 rs10017674 chr4:9967053 T/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.87 -0.58 1.53e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs854765 0.505 rs2955358 chr17:17946623 A/G cg04398451 chr17:18023971 MYO15A 0.34 5.42 0.44 2.98e-7 Total body bone mineral density; TGCT cis rs7666738 0.830 rs2114425 chr4:99023967 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.24 0.43 6.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs35306767 0.761 rs11253537 chr10:1010735 G/A cg18964960 chr10:1102726 WDR37 0.69 4.82 0.4 4.12e-6 Eosinophil percentage of granulocytes; TGCT cis rs4566357 1.000 rs3769637 chr2:227922623 T/C cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs6759518 0.655 rs1659682 chr2:27410735 C/T cg26210250 chr2:26863503 CIB4 -0.78 -4.46 -0.37 1.79e-5 Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs12540874 0.500 rs12719030 chr7:50485073 T/C cg18232548 chr7:50535776 DDC -0.39 -6.75 -0.52 4.98e-10 Systemic sclerosis; TGCT cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg10047753 chr17:41438598 NA 0.97 9.96 0.67 1.57e-17 Menopause (age at onset); TGCT cis rs7772486 0.686 rs6933161 chr6:146081369 G/A cg23711669 chr6:146136114 FBXO30 -0.89 -9.88 -0.66 2.48e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -8.69 -0.62 1.82e-14 Platelet count; TGCT cis rs9549367 0.713 rs9549352 chr13:113833221 A/G cg18105134 chr13:113819100 PROZ -0.47 -8.06 -0.59 5.42e-13 Platelet distribution width; TGCT cis rs1878931 0.501 rs42329 chr16:3425524 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.75 -7.11 -0.54 7.93e-11 Body mass index (adult); TGCT cis rs7698623 0.717 rs4693893 chr4:88797765 A/G cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs2836974 0.568 rs2836969 chr21:40648265 G/A cg06238570 chr21:40685208 BRWD1 -0.8 -9.0 -0.63 3.19e-15 Cognitive function; TGCT cis rs1552244 0.832 rs61056817 chr3:10027641 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.86 5.9 0.47 3.18e-8 Alzheimer's disease; TGCT cis rs4819052 0.851 rs4819049 chr21:46673086 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.59 4.72 0.39 6.28e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1401999 1.000 rs1402002 chr3:183642794 A/G cg01324343 chr3:183735012 ABCC5 0.78 10.02 0.67 1.14e-17 Anterior chamber depth; TGCT cis rs6570726 0.791 rs365747 chr6:145866784 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.752 rs62318905 chr4:99036103 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2730245 0.563 rs2709857 chr7:158685257 T/C cg11984989 chr7:158649758 WDR60 1.07 10.34 0.68 1.87e-18 Height; TGCT cis rs7811142 0.887 rs111972532 chr7:100069088 T/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.78 -0.66 4.27e-17 Platelet count; TGCT cis rs12477438 0.520 rs2632283 chr2:99776000 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs3087591 1.000 rs2952978 chr17:29474744 A/C cg24425628 chr17:29625626 OMG;NF1 0.47 7.52 0.56 9.75e-12 Hip circumference; TGCT cis rs3812831 0.661 rs2987458 chr13:114919835 A/G cg08824895 chr13:115047677 UPF3A 0.5 4.77 0.39 5.04e-6 Schizophrenia; TGCT cis rs7731657 0.510 rs986496 chr5:130282172 C/T cg08523029 chr5:130500466 HINT1 0.58 4.84 0.4 3.8e-6 Fasting plasma glucose; TGCT cis rs6815814 0.950 rs56289835 chr4:38811845 G/C cg02016764 chr4:38805732 TLR1 -0.36 -5.71 -0.46 7.91e-8 Breast cancer; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg26668828 chr6:292823 DUSP22 -0.85 -8.73 -0.62 1.48e-14 Menopause (age at onset); TGCT cis rs3733585 0.673 rs4459990 chr4:9954005 T/C cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7980687 0.527 rs28533432 chr12:123873242 C/T cg00376283 chr12:123451042 ABCB9 0.64 5.34 0.43 4.19e-7 Height;Educational attainment;Head circumference (infant); TGCT cis rs3772130 0.962 rs4280673 chr3:121526107 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg18538332 chr22:24372958 LOC391322 -0.92 -11.41 -0.72 4.6e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7959452 0.536 rs4761237 chr12:69776461 C/G cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs3540 0.533 rs1869179 chr15:90895564 A/C cg22089800 chr15:90895588 ZNF774 0.82 9.07 0.63 2.24e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs4478858 0.611 rs6425721 chr1:31714807 C/T cg00250761 chr1:31883323 NA -0.28 -4.93 -0.4 2.59e-6 Alcohol dependence; TGCT cis rs2742417 0.603 rs2742372 chr3:45783472 T/C cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2730245 0.527 rs924910 chr7:158672272 C/T cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs4499344 0.633 rs259260 chr19:33153261 G/A cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT cis rs9611565 0.625 rs9607819 chr22:41958862 C/G cg06481639 chr22:41940642 POLR3H -0.66 -5.58 -0.45 1.43e-7 Vitiligo; TGCT cis rs3749237 0.964 rs10865959 chr3:49891002 G/C cg10152585 chr3:50297680 NA 0.52 4.7 0.39 6.83e-6 Resting heart rate; TGCT cis rs727563 0.638 rs4820443 chr22:42193913 A/G cg13695892 chr22:41940480 POLR3H -0.8 -7.6 -0.56 6.36e-12 Crohn's disease;Inflammatory bowel disease; TGCT cis rs999943 0.774 rs12205634 chr6:33611667 C/G cg14003231 chr6:33640908 ITPR3 0.42 5.27 0.43 5.82e-7 Obesity (extreme); TGCT cis rs6545883 0.929 rs2593625 chr2:61668769 C/T cg15711740 chr2:61764176 XPO1 -0.56 -5.07 -0.41 1.42e-6 Tuberculosis; TGCT cis rs7726839 0.540 rs3749615 chr5:601485 C/T cg16624210 chr5:671434 TPPP 0.42 4.73 0.39 5.92e-6 Obesity-related traits; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.44 6.24 0.49 6.47e-9 Lymphocyte counts; TGCT cis rs13326165 0.760 rs390802 chr3:52431671 G/A cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg11494091 chr17:61959527 GH2 0.61 14.46 0.79 2.18e-28 Prudent dietary pattern; TGCT cis rs713587 0.525 rs11687089 chr2:25082926 T/C cg01884057 chr2:25150051 NA 0.3 5.66 0.45 9.78e-8 Body mass index in non-asthmatics; TGCT cis rs1865760 0.566 rs9295688 chr6:26084217 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs8179 0.593 rs6948097 chr7:92281953 C/T cg15732164 chr7:92237376 CDK6 -0.29 -5.06 -0.41 1.46e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs67073037 0.826 rs6728138 chr2:29138978 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs6684514 1.000 rs28372828 chr1:156253031 G/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7178572 1.000 rs62007299 chr15:77711719 G/A cg22256960 chr15:77711686 NA -0.95 -10.93 -0.7 6.95e-20 Type 2 diabetes; TGCT cis rs10089 1.000 rs10478796 chr5:127436187 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.79 7.6 0.56 6.47e-12 Ileal carcinoids; TGCT cis rs7586879 0.639 rs2033654 chr2:25103108 C/A cg01884057 chr2:25150051 NA 0.33 6.31 0.49 4.6e-9 Body mass index; TGCT cis rs6121246 0.609 rs1009453 chr20:30404840 C/G cg13852791 chr20:30311386 BCL2L1 0.81 7.58 0.56 7.06e-12 Mean corpuscular hemoglobin; TGCT cis rs10744422 0.858 rs2292136 chr12:123339344 A/G cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs71636778 0.570 rs34026565 chr1:27229976 T/C cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs2239547 0.618 rs13083728 chr3:52868445 G/A cg10802521 chr3:52805072 NEK4 -0.63 -5.99 -0.47 2.16e-8 Schizophrenia; TGCT trans rs7726839 0.540 rs74553517 chr5:665671 C/T cg11887960 chr12:57824829 NA 1.15 9.91 0.66 2.07e-17 Obesity-related traits; TGCT cis rs2153535 0.580 rs1414351 chr6:8476634 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs3782455 1.000 rs79001482 chr12:114403542 T/C cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT trans rs10802346 0.545 rs1361408 chr1:246410054 T/G cg22732515 chr19:44031385 ETHE1 0.97 8.08 0.59 4.79e-13 Fractional exhaled nitric oxide (childhood); TGCT cis rs7666738 0.830 rs4443295 chr4:99044935 G/A cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs40363 1.000 rs1635393 chr16:3520493 C/T cg05754148 chr16:3507555 NAT15 0.46 4.56 0.38 1.22e-5 Tuberculosis; TGCT cis rs2463822 1.000 rs11231050 chr11:62131660 C/G cg23876832 chr11:62092739 NA -0.62 -4.59 -0.38 1.09e-5 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg06634786 chr22:41940651 POLR3H -0.89 -8.16 -0.59 3.16e-13 Vitiligo; TGCT cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg09904177 chr6:26538194 HMGN4 0.69 6.73 0.52 5.6e-10 Intelligence (multi-trait analysis); TGCT cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs9650657 0.615 rs6601534 chr8:10691993 A/G cg16664915 chr8:10907788 XKR6 -0.29 -4.55 -0.38 1.25e-5 Neuroticism; TGCT cis rs34975555 0.527 rs2299596 chr8:17808730 A/G cg05315865 chr8:17013409 ZDHHC2 -0.64 -4.5 -0.37 1.53e-5 Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg26119090 chr2:26468346 HADHA;HADHB -0.93 -6.89 -0.53 2.52e-10 Gut microbiome composition (summer); TGCT cis rs12477438 0.520 rs11123765 chr2:99768064 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.28 0.77 1.43e-25 Chronic sinus infection; TGCT cis rs7264396 0.690 rs2425183 chr20:34450621 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg16325326 chr1:53192061 ZYG11B 0.5 5.56 0.45 1.56e-7 Monocyte count; TGCT cis rs6723226 0.764 rs176403 chr2:32637864 C/A cg02381751 chr2:32503542 YIPF4 -0.56 -5.13 -0.42 1.11e-6 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.885 rs28576202 chr21:46674684 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4654899 1.000 rs7554997 chr1:21400139 C/T cg01072550 chr1:21505969 NA -0.48 -7.71 -0.57 3.44e-12 Superior frontal gyrus grey matter volume; TGCT cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.7e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.636 rs77691549 chr8:58055126 G/T cg08280861 chr8:58055591 NA 0.49 5.52 0.44 1.85e-7 Developmental language disorder (linguistic errors); TGCT cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg07061783 chr6:25882402 NA -0.65 -6.41 -0.5 2.76e-9 Intelligence (multi-trait analysis); TGCT cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg14983838 chr19:29218262 NA 0.86 7.07 0.54 9.71e-11 Methadone dose in opioid dependence; TGCT cis rs4879913 0.801 rs7028425 chr9:35606738 C/G cg18130437 chr9:35658183 CCDC107;RMRP -0.46 -4.54 -0.38 1.32e-5 Electroencephalogram traits; TGCT cis rs6089829 0.632 rs62197308 chr20:61660705 T/C cg08045932 chr20:61659980 NA -0.31 -4.47 -0.37 1.76e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT trans rs1814175 0.817 rs1851858 chr11:49855638 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs4642101 0.640 rs9877049 chr3:12821231 A/G cg05775895 chr3:12838266 CAND2 0.92 11.11 0.71 2.53e-20 QRS complex (12-leadsum); TGCT cis rs10751667 0.961 rs7396670 chr11:929269 A/G cg06064525 chr11:970664 AP2A2 -0.31 -6.11 -0.48 1.19e-8 Alzheimer's disease (late onset); TGCT cis rs6460942 0.908 rs6978877 chr7:12232690 A/G cg06484146 chr7:12443880 VWDE -0.52 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs11626933 1.000 rs59905513 chr14:90749638 T/C cg14092571 chr14:90743983 NA -0.3 -6.13 -0.48 1.06e-8 Gut microbiota (bacterial taxa); TGCT cis rs9902453 0.765 rs8071576 chr17:28188554 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.85 8.11 0.59 4.19e-13 Coffee consumption (cups per day); TGCT cis rs11105298 0.891 rs3825330 chr12:89933710 C/T cg00757033 chr12:89920650 WDR51B 0.29 4.6 0.38 1.01e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs12477438 0.834 rs1563108 chr2:99701153 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.69 -6.1 -0.48 1.28e-8 Chronic sinus infection; TGCT cis rs854765 0.647 rs2056842 chr17:18009028 C/T cg04398451 chr17:18023971 MYO15A -0.38 -6.48 -0.5 1.91e-9 Total body bone mineral density; TGCT cis rs9527 0.590 rs3781281 chr10:104852648 A/G cg04362960 chr10:104952993 NT5C2 -0.68 -5.79 -0.46 5.33e-8 Arsenic metabolism; TGCT cis rs7760949 0.852 rs9475801 chr6:13933115 G/A cg27413430 chr6:13925136 RNF182 0.74 6.83 0.52 3.37e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg08219700 chr8:58056026 NA 0.39 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.647 rs34103231 chr15:76912690 A/G cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs9303401 0.527 rs12939313 chr17:56755616 A/T cg25039879 chr17:56429692 SUPT4H1 0.53 4.55 0.38 1.25e-5 Cognitive test performance; TGCT cis rs28595532 0.920 rs115271785 chr4:119735748 A/T cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs4478858 0.735 rs11576603 chr1:31774031 C/T cg00250761 chr1:31883323 NA -0.27 -4.94 -0.41 2.43e-6 Alcohol dependence; TGCT cis rs713587 0.571 rs563590 chr2:25331172 A/G cg01884057 chr2:25150051 NA -0.26 -5.01 -0.41 1.8e-6 Body mass index in non-asthmatics; TGCT cis rs6088590 1.000 rs910870 chr20:33292893 T/C cg06115741 chr20:33292138 TP53INP2 0.64 5.58 0.45 1.44e-7 Coronary artery disease; TGCT cis rs4523957 0.620 rs58187837 chr17:2073272 G/C cg16513277 chr17:2031491 SMG6 -0.2 -4.46 -0.37 1.8e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9303401 0.659 rs17822735 chr17:56620167 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs9467773 1.000 rs6932156 chr6:26571506 T/G cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.714 rs11784052 chr8:8671962 C/T cg08975724 chr8:8085496 FLJ10661 0.49 4.48 0.37 1.7e-5 Mood instability; TGCT cis rs12950390 0.853 rs11079792 chr17:45863311 T/C cg24803719 chr17:45855879 NA -0.49 -5.03 -0.41 1.64e-6 IgG glycosylation; TGCT cis rs7172809 0.643 rs16968930 chr15:77843434 T/A cg22256960 chr15:77711686 NA -0.47 -4.73 -0.39 5.89e-6 Glucose homeostasis traits; TGCT cis rs28386778 0.897 rs2584639 chr17:61863732 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT trans rs9650657 0.504 rs2409724 chr8:11041642 A/T cg15556689 chr8:8085844 FLJ10661 -0.85 -8.28 -0.6 1.65e-13 Neuroticism; TGCT cis rs3008870 1.000 rs2065000 chr1:67468124 G/C cg08660285 chr1:67390436 MIER1;WDR78 -1.07 -11.34 -0.71 6.75e-21 Lymphocyte percentage of white cells; TGCT cis rs2013441 1.000 rs2703806 chr17:20108239 A/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs12541335 0.639 rs3923439 chr8:22170079 G/A cg26039829 chr8:22132926 PIWIL2 0.26 4.96 0.41 2.32e-6 Hypertriglyceridemia; TGCT cis rs2180341 0.680 rs9388554 chr6:127576234 C/G cg27446573 chr6:127587934 RNF146 0.91 8.5 0.61 5.12e-14 Breast cancer; TGCT cis rs782590 0.764 rs2586969 chr2:55829392 G/C cg18811423 chr2:55921094 PNPT1 0.55 5.72 0.46 7.65e-8 Metabolic syndrome; TGCT cis rs478304 0.718 rs1151490 chr11:65390485 A/C cg17480646 chr11:65405466 SIPA1 0.55 7.19 0.54 5.48e-11 Acne (severe); TGCT cis rs4794202 0.534 rs10428 chr17:45915086 G/A cg02219949 chr17:45927392 SP6 0.37 4.47 0.37 1.76e-5 Alzheimer's disease (cognitive decline); TGCT cis rs6088590 1.000 rs6120708 chr20:33335526 G/A cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs350251 0.833 rs350272 chr16:12234773 A/C cg02910054 chr16:12241554 SNX29 -0.37 -5.13 -0.42 1.08e-6 Intelligence (multi-trait analysis); TGCT cis rs425277 1.000 rs262672 chr1:2080813 G/T cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs9814567 1.000 rs2056604 chr3:134312648 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11098499 0.909 rs11723757 chr4:120299669 C/T cg09307838 chr4:120376055 NA 0.67 6.46 0.5 2.15e-9 Corneal astigmatism; TGCT cis rs2439831 0.850 rs524417 chr15:43772374 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.76 5.22 0.42 7.24e-7 Lung cancer in ever smokers; TGCT cis rs2456568 1.000 rs2456568 chr11:93691332 A/T cg14065697 chr11:93583672 C11orf90 -0.37 -4.55 -0.38 1.27e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4642101 0.855 rs9873475 chr3:12845422 A/G cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs12142240 0.698 rs17357628 chr1:46808462 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs2361718 0.501 rs12944619 chr17:78144109 T/C cg09238746 chr17:78121135 EIF4A3 -1.1 -11.38 -0.71 5.62e-21 Yeast infection; TGCT cis rs736408 0.677 rs1042779 chr3:52821011 A/G cg10802521 chr3:52805072 NEK4 -0.7 -8.28 -0.6 1.7e-13 Bipolar disorder; TGCT cis rs751728 1.000 rs2296748 chr6:33745071 C/T cg00334056 chr6:33755658 LEMD2 -0.25 -4.59 -0.38 1.08e-5 Crohn's disease; TGCT cis rs797680 0.821 rs2391254 chr1:93795166 A/T cg17826107 chr1:92977322 EVI5 -0.23 -5.14 -0.42 1.05e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs7772486 0.686 rs9376956 chr6:145949844 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2204008 0.668 rs1619009 chr12:38120485 G/A cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs8103278 1.000 rs7252126 chr19:46302374 T/A cg11657440 chr19:46296263 DMWD -0.59 -5.71 -0.46 7.83e-8 Coronary artery disease; TGCT cis rs17818399 0.788 rs13013245 chr2:46806086 T/C cg26688816 chr2:46740690 ATP6V1E2 -0.53 -5.24 -0.43 6.72e-7 Height; TGCT cis rs4499344 0.556 rs259217 chr19:33138368 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.26 0.6 1.84e-13 Mean platelet volume; TGCT trans rs2469997 1.000 rs2470017 chr8:120361534 G/A cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs7086627 0.506 rs10749575 chr10:82136921 C/T cg01528321 chr10:82214614 TSPAN14 0.51 4.45 0.37 1.91e-5 Post bronchodilator FEV1; TGCT cis rs6121246 0.559 rs6060952 chr20:30382108 T/G cg10886678 chr20:30946050 ASXL1 -0.53 -4.5 -0.37 1.55e-5 Mean corpuscular hemoglobin; TGCT cis rs1865760 0.533 rs1408270 chr6:25873184 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.59 4.68 0.39 7.54e-6 Height; TGCT cis rs11190604 1.000 rs10883510 chr10:102297018 C/T cg16342193 chr10:102329863 NA -0.43 -5.3 -0.43 5.03e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs17826219 0.500 rs28452421 chr17:29083980 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs11677203 1.000 rs11685890 chr2:12564292 C/T cg00419568 chr2:11919532 LPIN1 -0.2 -4.55 -0.38 1.26e-5 Electroencephalogram traits; TGCT cis rs13223928 0.565 rs10951053 chr7:3155579 C/T cg19214707 chr7:3157722 NA -0.46 -6.8 -0.52 3.87e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs6690583 0.623 rs6672362 chr1:85454881 C/G cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs7589728 0.620 rs76687350 chr2:88473832 G/A cg04511125 chr2:88470314 THNSL2 0.63 4.98 0.41 2.04e-6 Plasma clusterin levels; TGCT cis rs6430585 0.878 rs9677760 chr2:136538939 T/A cg07169764 chr2:136633963 MCM6 -0.88 -7.8 -0.57 2.16e-12 Corneal structure; TGCT cis rs7940866 0.646 rs10894293 chr11:130824213 C/T cg12179176 chr11:130786555 SNX19 -0.61 -5.77 -0.46 5.87e-8 Schizophrenia; TGCT trans rs11764590 0.715 rs62444907 chr7:2083267 C/T cg25206134 chr2:45395956 NA 0.97 6.71 0.52 6.05e-10 Neuroticism; TGCT cis rs7208859 0.623 rs8067035 chr17:29102188 T/C cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg09436375 chr6:42928200 GNMT -0.4 -5.16 -0.42 9.7e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7169223 0.653 rs3971703 chr15:79092481 G/C cg21242079 chr15:79101063 ADAMTS7 0.35 5.57 0.45 1.53e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs7647973 1.000 rs9860055 chr3:49506900 C/T cg07636037 chr3:49044803 WDR6 -0.7 -5.73 -0.46 7.08e-8 Menarche (age at onset); TGCT cis rs79349575 0.783 rs61576918 chr17:46985593 A/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs9308731 0.644 rs1439287 chr2:111871897 G/A cg04202892 chr2:111875749 ACOXL 0.54 6.22 0.49 7.07e-9 Chronic lymphocytic leukemia; TGCT cis rs56235845 0.665 rs4976685 chr5:176766177 C/T cg16006841 chr5:176797999 RGS14 -0.52 -7.59 -0.56 6.54e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg26338869 chr17:61819248 STRADA -0.57 -5.23 -0.43 7.02e-7 Prudent dietary pattern; TGCT trans rs1814175 0.676 rs11040647 chr11:49935947 A/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs66573146 1.000 rs28384174 chr4:6961107 G/T cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs492146 0.729 rs644100 chr6:52842371 A/C cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg08392591 chr16:89556376 ANKRD11 0.57 5.2 0.42 8.01e-7 Multiple myeloma (IgH translocation); TGCT cis rs4689388 0.926 rs10937719 chr4:6295322 C/G cg25554036 chr4:6271136 WFS1 0.54 7.0 0.53 1.42e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7192750 0.652 rs150617 chr16:72139396 T/C cg06353428 chr16:71660113 MARVELD3 1.02 5.25 0.43 6.49e-7 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs13424612 0.896 rs12466838 chr2:240893427 G/A cg26363272 chr2:240904871 NDUFA10 0.28 4.63 0.38 8.95e-6 Odorant perception (isobutyraldehyde); TGCT cis rs769267 1.000 rs2074089 chr19:19449603 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg11890956 chr21:40555474 PSMG1 1.11 12.17 0.74 6.69e-23 Cognitive function; TGCT cis rs72843506 0.722 rs5025290 chr17:20205817 A/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.86 -0.4 3.54e-6 Schizophrenia; TGCT cis rs7208859 0.673 rs79541516 chr17:29240583 C/T cg18442181 chr17:29233375 C17orf42 -0.79 -4.72 -0.39 6.22e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9467773 0.595 rs9366657 chr6:26434914 C/G cg15659132 chr6:26577336 NA 0.43 4.48 0.37 1.65e-5 Intelligence (multi-trait analysis); TGCT cis rs10791323 0.660 rs10791332 chr11:133732150 A/G cg15485101 chr11:133734466 NA 0.37 5.0 0.41 1.9e-6 Childhood ear infection; TGCT cis rs6032067 0.516 rs6104085 chr20:43901302 A/C cg16667508 chr20:43936853 MATN4;RBPJL -0.38 -5.96 -0.47 2.38e-8 Blood protein levels; TGCT cis rs4711350 0.871 rs1998949 chr6:33721457 T/C cg18005901 chr6:33739558 LEMD2 -0.46 -5.04 -0.41 1.62e-6 Schizophrenia; TGCT cis rs968451 0.789 rs1003643 chr22:39676494 T/G cg17798944 chr22:39715225 SNORD43;RPL3 0.75 7.4 0.55 1.77e-11 Primary biliary cholangitis; TGCT cis rs2806561 0.704 rs2806570 chr1:23527005 C/T cg12483005 chr1:23474871 LUZP1 -0.43 -5.35 -0.43 4.02e-7 Height; TGCT cis rs12497850 0.897 rs9681717 chr3:48872998 A/G cg06212747 chr3:49208901 KLHDC8B 0.6 5.48 0.44 2.32e-7 Parkinson's disease; TGCT cis rs2836974 0.602 rs8130854 chr21:40707041 G/A cg06238570 chr21:40685208 BRWD1 -0.82 -8.76 -0.62 1.19e-14 Cognitive function; TGCT cis rs7635838 0.684 rs2594966 chr3:11325276 A/G cg00170343 chr3:11313890 ATG7 -0.64 -6.32 -0.49 4.28e-9 HDL cholesterol; TGCT cis rs854765 0.655 rs4470201 chr17:17844870 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs2153535 0.580 rs718503 chr6:8527463 A/T cg07606381 chr6:8435919 SLC35B3 0.53 4.97 0.41 2.22e-6 Motion sickness; TGCT cis rs681343 0.746 rs633372 chr19:49209226 G/A cg05248581 chr19:49925731 PTH2 0.42 4.57 0.38 1.16e-5 Lung adenocarcinoma;Primary sclerosing cholangitis;Childhood ear infection; TGCT cis rs9302001 0.881 rs9524627 chr13:95469890 A/G cg07483244 chr13:95358924 NA -0.34 -4.47 -0.37 1.71e-5 Panic disorder; TGCT cis rs7845219 0.539 rs10441538 chr8:95868608 G/A cg13393036 chr8:95962371 TP53INP1 -0.49 -5.86 -0.47 3.92e-8 Type 2 diabetes; TGCT cis rs9549260 0.664 rs1360719 chr13:41225874 G/C cg21288729 chr13:41239152 FOXO1 1.01 10.71 0.69 2.36e-19 Red blood cell count; TGCT cis rs7914558 1.000 rs7920251 chr10:104950197 C/T cg15744005 chr10:104629667 AS3MT -0.39 -4.84 -0.4 3.83e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.09 -0.42 1.29e-6 Electroencephalogram traits; TGCT trans rs2688608 0.901 rs2675671 chr10:75632760 C/T cg13918328 chr10:52500089 ASAH2B 0.64 6.76 0.52 4.87e-10 Inflammatory bowel disease; TGCT cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs1801251 1.000 rs3817311 chr2:233612557 C/T cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs2147959 0.882 rs6666241 chr1:228629759 A/G cg22700015 chr1:228743131 NA -0.57 -4.53 -0.38 1.35e-5 Adult asthma; TGCT cis rs9916302 0.706 rs9646419 chr17:37597185 A/G cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs597539 0.652 rs557625 chr11:68634722 G/A cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28595532 1.000 rs17323012 chr4:119605671 A/G cg14228332 chr4:119757509 SEC24D 1.04 5.39 0.44 3.43e-7 Cannabis dependence symptom count; TGCT cis rs1008375 0.966 rs6449329 chr4:17703677 T/C cg10189774 chr4:17578691 LAP3 0.52 4.47 0.37 1.73e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7100689 0.577 rs756208 chr10:82041751 A/G cg01528321 chr10:82214614 TSPAN14 0.7 6.78 0.52 4.43e-10 Post bronchodilator FEV1; TGCT cis rs1903068 0.597 rs10013070 chr4:55997201 A/G cg09978860 chr4:56023921 NA 0.54 5.58 0.45 1.43e-7 Endometriosis; TGCT cis rs11122272 0.735 rs2247132 chr1:231493359 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -6.83 -0.52 3.39e-10 Hemoglobin concentration; TGCT cis rs651907 0.557 rs7651406 chr3:101393296 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.24 0.43 6.66e-7 Colorectal cancer; TGCT cis rs6940638 0.606 rs6456771 chr6:27232395 G/A cg26531700 chr6:26746687 NA -0.66 -5.29 -0.43 5.31e-7 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.659 rs12602389 chr17:56779778 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs6728642 1.000 rs113863815 chr2:97657813 A/G cg26665480 chr2:98280029 ACTR1B -0.96 -5.36 -0.43 3.91e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs62380364 0.602 rs606393 chr5:88058163 T/C cg22951263 chr5:87985283 NA -0.59 -6.27 -0.49 5.5e-9 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg11494091 chr17:61959527 GH2 0.6 14.31 0.79 5.05e-28 Prudent dietary pattern; TGCT cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg13012494 chr21:47604986 C21orf56 0.38 4.56 0.38 1.21e-5 Testicular germ cell tumor; TGCT cis rs9611519 0.929 rs4821991 chr22:41440683 T/C cg13695892 chr22:41940480 POLR3H -0.55 -4.9 -0.4 2.99e-6 Neuroticism; TGCT cis rs7674212 0.510 rs55715738 chr4:104130189 A/G cg16532752 chr4:104119610 CENPE -0.61 -5.56 -0.45 1.61e-7 Type 2 diabetes; TGCT cis rs2677744 0.626 rs868547 chr15:91498760 G/A cg23684204 chr15:91497937 RCCD1 0.41 6.39 0.5 2.98e-9 Attention deficit hyperactivity disorder; TGCT cis rs17376456 1.000 rs13163610 chr5:93548877 A/C cg25358565 chr5:93447407 FAM172A 0.94 7.65 0.57 4.96e-12 Diabetic retinopathy; TGCT cis rs9611565 0.918 rs12484074 chr22:41752747 G/A cg17554472 chr22:41940697 POLR3H -0.52 -5.17 -0.42 9.26e-7 Vitiligo; TGCT cis rs7172809 0.524 rs4886857 chr15:77576567 T/C cg22256960 chr15:77711686 NA -0.47 -4.61 -0.38 9.99e-6 Glucose homeostasis traits; TGCT cis rs28595532 0.844 rs116721336 chr4:119536538 A/G cg14228332 chr4:119757509 SEC24D 1.0 5.75 0.46 6.54e-8 Cannabis dependence symptom count; TGCT cis rs2639990 0.744 rs640261 chr18:72905808 C/T cg03972071 chr18:72917163 ZADH2 0.8 5.4 0.44 3.3e-7 Vascular endothelial growth factor levels; TGCT cis rs13108904 0.875 rs73069950 chr4:1276045 C/A cg05665937 chr4:1216051 CTBP1 -0.24 -4.55 -0.38 1.26e-5 Obesity-related traits; TGCT cis rs17534004 1.000 rs35858501 chr13:31472120 C/T cg13251181 chr13:31481184 C13orf33 0.36 4.99 0.41 1.97e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs11785400 0.793 rs4736362 chr8:143741381 G/A cg24634471 chr8:143751801 JRK 0.56 5.53 0.44 1.81e-7 Schizophrenia; TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg09060608 chr5:178986726 RUFY1 0.53 5.89 0.47 3.36e-8 Lung cancer; TGCT cis rs4746818 0.901 rs7914719 chr10:70903832 T/C cg11621586 chr10:70884670 VPS26A 1.22 10.78 0.7 1.56e-19 Left atrial antero-posterior diameter; TGCT cis rs10276303 1.000 rs10256447 chr7:3338689 A/G cg26053068 chr7:2691072 TTYH3 -0.17 -4.54 -0.38 1.29e-5 Dupuytren's disease; TGCT cis rs12682352 0.652 rs3789843 chr8:8724257 C/T cg06636001 chr8:8085503 FLJ10661 0.68 6.25 0.49 5.99e-9 Neuroticism; TGCT cis rs2688608 0.530 rs71507081 chr10:75493136 G/A cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs611744 0.647 rs587340 chr8:109246032 C/A cg21045802 chr8:109455806 TTC35 0.74 7.37 0.55 2.07e-11 Dupuytren's disease; TGCT cis rs12711979 0.765 rs7559461 chr2:3818623 G/A cg17052675 chr2:3827356 NA -0.4 -7.89 -0.58 1.34e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs2836974 0.897 rs1984022 chr21:40596085 G/A cg11644478 chr21:40555479 PSMG1 1.0 10.6 0.69 4.32e-19 Cognitive function; TGCT cis rs896854 0.875 rs4735333 chr8:95955074 G/A cg13393036 chr8:95962371 TP53INP1 -0.63 -8.79 -0.62 1.04e-14 Type 2 diabetes; TGCT cis rs12950390 0.820 rs58391889 chr17:45865959 A/G cg06532163 chr17:45867833 NA 0.35 5.53 0.44 1.84e-7 IgG glycosylation; TGCT cis rs17376456 0.569 rs7736892 chr5:93205597 G/A cg21475434 chr5:93447410 FAM172A -0.7 -5.15 -0.42 1.02e-6 Diabetic retinopathy; TGCT cis rs801193 0.613 rs2659900 chr7:66184443 G/C cg18876405 chr7:65276391 NA 0.33 4.87 0.4 3.27e-6 Aortic root size; TGCT cis rs6840360 0.571 rs62327272 chr4:152545090 A/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs9393692 0.676 rs1543681 chr6:26187783 G/T cg00631329 chr6:26305371 NA -0.32 -4.78 -0.39 4.81e-6 Educational attainment; TGCT cis rs7945705 0.791 rs10769958 chr11:8815115 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.42 -4.64 -0.38 8.87e-6 Hemoglobin concentration; TGCT cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs1215050 0.765 rs1530905 chr4:98805705 A/G cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs916888 0.773 rs169201 chr17:44790203 A/G cg22433210 chr17:43662623 NA 1.06 7.29 0.55 3.2e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs617791 0.530 rs55947178 chr11:65754230 G/A cg09783858 chr11:65769428 EIF1AD;BANF1 0.5 4.56 0.38 1.2e-5 Breast cancer; TGCT cis rs6570726 0.791 rs9376945 chr6:145828080 T/A cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg10802521 chr3:52805072 NEK4 0.78 10.0 0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs2239547 0.563 rs4687560 chr3:52898121 T/G cg11645453 chr3:52864694 ITIH4 0.32 5.48 0.44 2.27e-7 Schizophrenia; TGCT cis rs7611238 0.560 rs4677843 chr3:195141022 T/C cg27323046 chr3:195102265 ACAP2 0.39 5.15 0.42 1.01e-6 Body mass index; TGCT cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs17384381 1.000 rs71652696 chr1:85831792 A/C cg16011679 chr1:85725395 C1orf52 0.91 6.64 0.51 8.59e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2115630 0.905 rs1975277 chr15:85329558 C/T cg11189052 chr15:85197271 WDR73 -0.62 -5.98 -0.47 2.2e-8 P wave terminal force; TGCT cis rs11614913 0.551 rs1867297 chr12:54396971 A/G cg27482031 chr12:54402697 HOXC8 -0.56 -4.89 -0.4 3.03e-6 Waist circumference adjusted for body mass index; TGCT cis rs7017914 1.000 rs13252719 chr8:71734569 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs6840360 0.571 rs11099823 chr4:152510565 T/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs13235720 chr7:116113663 T/C cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs3733631 1.000 rs3733631 chr4:104641103 G/C cg24090629 chr4:104641072 TACR3 -0.78 -6.33 -0.49 4.08e-9 Menarche (age at onset); TGCT cis rs1218582 0.772 rs10796935 chr1:154891363 G/T cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs41298997 1 rs41298997 chr1:206655331 C/T cg11166312 chr1:206654246 IKBKE 0.26 5.88 0.47 3.61e-8 Psoriasis; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs854765 0.547 rs7212167 chr17:17913504 G/A cg09796270 chr17:17721594 SREBF1 0.25 5.04 0.41 1.61e-6 Total body bone mineral density; TGCT cis rs4478037 0.749 rs6550204 chr3:33107645 C/T cg19404215 chr3:33155277 CRTAP -0.96 -5.69 -0.46 8.54e-8 Major depressive disorder; TGCT cis rs244731 0.959 rs10037110 chr5:176658066 A/T cg16006841 chr5:176797999 RGS14 -0.56 -7.34 -0.55 2.42e-11 Urate levels in lean individuals; TGCT cis rs11785400 1.000 rs6995314 chr8:143749718 A/G cg10596483 chr8:143751796 JRK -0.58 -6.14 -0.48 1.01e-8 Schizophrenia; TGCT cis rs6951245 0.580 rs10257426 chr7:1213694 G/A cg23708337 chr7:1209742 NA 0.6 5.76 0.46 6.27e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17221829 0.681 rs75322840 chr11:89390394 T/A cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs7666738 0.830 rs7663924 chr4:99037679 A/G cg17366294 chr4:99064904 C4orf37 -0.69 -7.05 -0.54 1.09e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 1.000 rs4128740 chr3:40519532 C/A cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs2153535 0.580 rs1414344 chr6:8471365 C/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs797680 0.754 rs12118230 chr1:93651461 T/G cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.89e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs1005277 0.579 rs2474569 chr10:38383491 C/G cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.13e-14 Extrinsic epigenetic age acceleration; TGCT cis rs9467773 0.935 rs4573 chr6:26546808 A/G cg05738196 chr6:26577821 NA 0.82 10.56 0.69 5.35e-19 Intelligence (multi-trait analysis); TGCT cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg26531700 chr6:26746687 NA -0.68 -6.72 -0.52 5.79e-10 Schizophrenia; TGCT cis rs3008870 1.000 rs11208976 chr1:67434411 A/G cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs1372520 0.684 rs1837891 chr4:90736131 C/G cg15133208 chr4:90757351 SNCA 0.51 6.08 0.48 1.35e-8 Neuroticism; TGCT cis rs9556958 0.708 rs9513435 chr13:99160334 C/G cg07423050 chr13:99094983 FARP1 -0.23 -4.89 -0.4 3.02e-6 Educational attainment (years of education); TGCT cis rs7666738 0.830 rs35276471 chr4:99068691 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs548181 0.536 rs503287 chr11:125461788 C/T cg03464685 chr11:125439445 EI24 1.18 9.17 0.64 1.28e-15 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7659604 0.560 rs769238 chr4:122744942 G/A cg06713675 chr4:122721982 EXOSC9 -0.69 -9.7 -0.66 6.92e-17 Type 2 diabetes; TGCT cis rs4242434 0.854 rs3735893 chr8:22452704 A/G cg03733263 chr8:22462867 KIAA1967 1.09 17.94 0.85 2.96e-36 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg10150615 chr22:24372951 LOC391322 -1.01 -13.09 -0.76 3.96e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11098499 0.818 rs55825515 chr4:120486402 A/G cg09307838 chr4:120376055 NA 0.73 6.97 0.53 1.69e-10 Corneal astigmatism; TGCT cis rs1519814 0.616 rs2326428 chr8:121011363 A/G cg22335954 chr8:121166405 COL14A1 -0.36 -4.52 -0.38 1.44e-5 Breast cancer; TGCT cis rs460214 0.564 rs458465 chr21:40024644 A/T cg05519781 chr21:40033154 ERG -0.52 -4.69 -0.39 6.96e-6 Response to cognitive-behavioural therapy in anxiety disorder; TGCT cis rs2721195 0.845 rs756627 chr8:145737286 G/A cg15320075 chr8:145703422 NA 0.69 6.68 0.51 7.07e-10 Age at first birth; TGCT cis rs9303401 0.538 rs2240259 chr17:56458129 A/C cg25039879 chr17:56429692 SUPT4H1 0.61 5.23 0.42 7.07e-7 Cognitive test performance; TGCT cis rs8072100 0.846 rs4264433 chr17:45737275 A/T cg08085267 chr17:45401833 C17orf57 0.47 5.12 0.42 1.11e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.73 0.39 6.13e-6 Schizophrenia; TGCT cis rs9611565 0.802 rs9611571 chr22:41784867 G/A cg06481639 chr22:41940642 POLR3H -0.61 -5.49 -0.44 2.17e-7 Vitiligo; TGCT cis rs9329289 0.888 rs11251273 chr10:2540300 G/C cg15501526 chr10:2543763 NA 0.4 4.79 0.39 4.76e-6 Age-related hearing impairment; TGCT cis rs1867631 1.000 rs10789213 chr1:67128201 T/C cg13052034 chr1:66999238 SGIP1 0.57 4.87 0.4 3.32e-6 Menopause (age at onset); TGCT cis rs4730250 0.554 rs112665932 chr7:106916121 A/G cg02696742 chr7:106810147 HBP1 -0.72 -5.29 -0.43 5.34e-7 Osteoarthritis; TGCT cis rs17384381 0.953 rs2284797 chr1:85792383 C/T cg16011679 chr1:85725395 C1orf52 0.81 6.34 0.49 3.82e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4595586 0.545 rs12823586 chr12:39391677 C/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs3809566 0.676 rs11071719 chr15:63329875 C/A cg08198488 chr15:63333792 TPM1 -0.34 -5.11 -0.42 1.18e-6 Platelet count; TGCT cis rs28374715 0.532 rs11070328 chr15:41651569 T/C cg18705301 chr15:41695430 NDUFAF1 -0.92 -15.84 -0.82 1.44e-31 Ulcerative colitis; TGCT cis rs28595532 0.920 rs28797314 chr4:119783044 A/G cg14228332 chr4:119757509 SEC24D 1.19 6.66 0.51 8.07e-10 Cannabis dependence symptom count; TGCT cis rs2295359 0.892 rs11209005 chr1:67618678 A/G cg08029281 chr1:67600428 NA 0.39 4.57 0.38 1.17e-5 Psoriasis; TGCT cis rs950169 0.840 rs35522895 chr15:84928049 G/A cg17173187 chr15:85201210 NMB 0.52 5.32 0.43 4.75e-7 Schizophrenia; TGCT cis rs2019216 0.564 rs1518053 chr17:21924272 G/T cg22648282 chr17:21454238 C17orf51 -0.56 -5.45 -0.44 2.57e-7 Pelvic organ prolapse; TGCT cis rs2412208 0.565 rs11120822 chr1:7113112 G/C cg20434152 chr1:7120926 CAMTA1 -0.31 -5.07 -0.41 1.42e-6 Survival in sporadic amyotrophic lateral sclerosis; TGCT cis rs9297145 0.585 rs62473049 chr7:98777685 T/C cg05967295 chr7:98741636 SMURF1 -0.68 -8.35 -0.6 1.12e-13 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs11785400 1.000 rs6995314 chr8:143749718 A/G cg24634471 chr8:143751801 JRK -0.58 -6.18 -0.49 8.5e-9 Schizophrenia; TGCT cis rs6547741 0.967 rs4665999 chr2:27834444 T/C cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs11696845 0.626 rs6073537 chr20:43378270 A/G cg25301532 chr20:43378953 KCNK15 -0.47 -5.15 -0.42 9.92e-7 Obesity-related traits; TGCT cis rs9985766 0.958 rs62339879 chr4:150989105 A/G cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs2116941 1.000 rs2033493 chr19:10340854 A/C cg01850179 chr19:10340795 S1PR2 -0.74 -9.93 -0.67 1.82e-17 Pulse pressure; TGCT cis rs1552244 0.882 rs55962400 chr3:10044457 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.22 0.49 7.14e-9 Alzheimer's disease; TGCT cis rs288326 0.561 rs79096460 chr2:183798677 A/G cg09997497 chr2:183902928 NCKAP1 1.12 5.0 0.41 1.88e-6 Blood protein levels; TGCT cis rs12478296 0.901 rs7423119 chr2:243005488 T/A cg06360820 chr2:242988706 NA -0.6 -4.96 -0.41 2.23e-6 Obesity-related traits; TGCT cis rs3741151 1.000 rs3741151 chr11:73020846 G/T cg17517138 chr11:73019481 ARHGEF17 1.17 5.55 0.45 1.67e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs921968 0.643 rs2303561 chr2:219527005 C/T cg02176678 chr2:219576539 TTLL4 -0.38 -5.47 -0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs1670533 1.000 rs13135215 chr4:1054364 A/G cg20887711 chr4:1340912 KIAA1530 0.72 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs2535633 0.631 rs2465101 chr3:52991307 A/T cg11645453 chr3:52864694 ITIH4 -0.27 -5.02 -0.41 1.77e-6 Body mass index; TGCT cis rs2836950 0.565 rs2836943 chr21:40592611 C/T cg06238570 chr21:40685208 BRWD1 -0.6 -6.21 -0.49 7.27e-9 Menarche (age at onset); TGCT cis rs7216064 0.953 rs62086044 chr17:65970837 G/T cg12091567 chr17:66097778 LOC651250 -0.79 -5.99 -0.47 2.07e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg09704166 chr2:114031854 PAX8;LOC440839 -0.33 -4.9 -0.4 2.95e-6 Lymphocyte counts; TGCT cis rs1865760 0.964 rs3799373 chr6:25929173 A/C cg16482183 chr6:26056742 HIST1H1C 0.51 4.57 0.38 1.16e-5 Height; TGCT cis rs116095464 0.558 rs9312979 chr5:222057 A/C cg22857025 chr5:266934 NA -0.34 -6.6 -0.51 1.09e-9 Breast cancer; TGCT cis rs2439831 1.000 rs101094 chr15:43787322 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.51 0.44 1.95e-7 Lung cancer in ever smokers; TGCT cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg22963979 chr7:1858916 MAD1L1 -0.42 -6.99 -0.53 1.51e-10 Schizophrenia; TGCT cis rs9303401 0.614 rs66480139 chr17:57101538 G/A cg25039879 chr17:56429692 SUPT4H1 0.54 4.8 0.4 4.57e-6 Cognitive test performance; TGCT cis rs9611565 0.592 rs5996037 chr22:41965292 A/G cg06481639 chr22:41940642 POLR3H -0.67 -5.71 -0.46 7.87e-8 Vitiligo; TGCT cis rs9467711 0.606 rs12173854 chr6:26371679 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs4766566 0.568 rs11065857 chr12:111739500 A/G cg10833066 chr12:111807467 FAM109A 0.4 7.51 0.56 1.01e-11 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT trans rs783396 0.688 rs1676008 chr6:106999132 A/G cg09013229 chr1:225332226 DNAH14 -0.58 -6.83 -0.52 3.35e-10 Stroke; TGCT cis rs75059851 1.000 rs3802924 chr11:133827733 A/C cg14047540 chr11:133829660 NA -0.58 -5.23 -0.43 6.87e-7 Schizophrenia; TGCT cis rs910316 1.000 rs2098297 chr14:75619118 G/T cg11812906 chr14:75593930 NEK9 -0.74 -7.31 -0.55 2.84e-11 Height; TGCT cis rs11098499 0.657 rs71614442 chr4:120379346 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs651907 0.514 rs34301719 chr3:101417993 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.56 5.02 0.41 1.71e-6 Colorectal cancer; TGCT cis rs595982 0.559 rs17272680 chr19:49364511 A/G cg21252483 chr19:49399788 TULP2 0.42 6.44 0.5 2.44e-9 Red cell distribution width; TGCT cis rs7552404 0.628 rs5745442 chr1:76342858 T/G cg10523679 chr1:76189770 ACADM 0.84 7.71 0.57 3.49e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7201929 1.000 rs11644151 chr16:28895660 G/A cg09754948 chr16:28834200 ATXN2L -0.63 -4.9 -0.4 2.93e-6 QT interval; TGCT cis rs11711311 0.955 rs9860642 chr3:113419211 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.81 -7.2 -0.54 5e-11 IgG glycosylation; TGCT cis rs9733 0.621 rs12746899 chr1:150579678 A/T cg13175981 chr1:150552382 MCL1 0.54 6.16 0.48 9.42e-9 Tonsillectomy; TGCT cis rs35883536 0.566 rs10783141 chr1:101043897 G/A cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.11e-12 Monocyte count; TGCT cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs916888 0.610 rs199444 chr17:44818276 T/C cg17911788 chr17:44343683 NA -0.5 -5.75 -0.46 6.61e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6582630 0.502 rs11181210 chr12:38298069 G/A cg26384229 chr12:38710491 ALG10B 0.8 7.08 0.54 9.28e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs12681287 0.577 rs10481197 chr8:87546551 A/T cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT trans rs1814175 0.669 rs12364577 chr11:49707361 A/C cg03929089 chr4:120376271 NA -0.6 -6.95 -0.53 1.88e-10 Height; TGCT cis rs7147624 1.000 rs10873192 chr14:66110653 A/G cg03016385 chr14:66212404 NA -0.49 -7.08 -0.54 9.33e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs73198271 0.653 rs10087633 chr8:8660444 A/G cg06636001 chr8:8085503 FLJ10661 -0.6 -4.47 -0.37 1.78e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2361718 0.522 rs11867921 chr17:78121170 G/T cg21238619 chr17:78079768 GAA -0.36 -4.54 -0.38 1.32e-5 Yeast infection; TGCT cis rs6752107 0.967 rs36001488 chr2:234185267 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.73 0.39 6.08e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2458413 0.542 rs35723041 chr8:105369123 A/C cg04554929 chr8:105342491 NA 0.49 5.79 0.46 5.35e-8 Paget's disease; TGCT cis rs644799 0.965 rs11021305 chr11:95498269 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.93 11.21 0.71 1.39e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs921968 0.510 rs2577761 chr2:219462500 G/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs351855 0.642 rs2546095 chr5:176509584 G/T cg26069374 chr5:176757514 NA -0.2 -4.58 -0.38 1.12e-5 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2455799 0.613 rs1969095 chr3:15733552 C/T cg16303742 chr3:15540471 COLQ -0.26 -4.89 -0.4 3.1e-6 Mean platelet volume; TGCT cis rs319204 0.843 rs488183 chr5:146280359 T/C cg25021259 chr5:146258546 PPP2R2B 0.35 4.56 0.38 1.23e-5 Schizophrenia; TGCT cis rs3847687 1.000 rs11061291 chr12:131518875 C/T cg25772418 chr12:131519998 GPR133 -0.31 -5.35 -0.43 4.01e-7 Longevity; TGCT cis rs7523273 0.597 rs6657476 chr1:207960104 G/T cg22525895 chr1:207977042 MIR29B2 -0.46 -6.74 -0.52 5.2400000000000005e-10 Schizophrenia; TGCT trans rs7618501 0.699 rs1062633 chr3:49924940 T/C cg21659725 chr3:3221576 CRBN 0.77 9.18 0.64 1.23e-15 Intelligence (multi-trait analysis); TGCT cis rs7639513 0.545 rs55977822 chr3:12704438 C/A cg23032965 chr3:12705835 RAF1 0.75 6.87 0.52 2.8e-10 Itch intensity from mosquito bite; TGCT cis rs78456975 0.527 rs10184112 chr2:1571112 A/G cg12573674 chr2:1569213 NA -0.49 -5.3 -0.43 5.1e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg03517284 chr6:25882590 NA 0.53 5.48 0.44 2.3e-7 Blood metabolite levels; TGCT cis rs6570726 0.846 rs7773939 chr6:145927384 C/T cg13319975 chr6:146136371 FBXO30 0.49 4.49 0.37 1.6e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs875971 1.000 rs6970030 chr7:65968679 T/C cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs2066819 1.000 rs58852079 chr12:56706922 A/C cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs6450176 0.625 rs3822499 chr5:53289459 C/G ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.58 -0.45 1.45e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7647973 1.000 rs3866330 chr3:49582994 T/C cg07636037 chr3:49044803 WDR6 0.6 4.96 0.41 2.22e-6 Menarche (age at onset); TGCT cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg09904177 chr6:26538194 HMGN4 0.66 6.33 0.49 3.99e-9 Intelligence (multi-trait analysis); TGCT cis rs7412746 0.634 rs2124952 chr1:150923774 T/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs344364 0.511 rs2906912 chr16:1953151 G/A cg26617929 chr16:1858877 NA -0.26 -4.66 -0.39 8.04e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7666738 0.830 rs4441757 chr4:98927059 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2836950 0.545 rs2836922 chr21:40516308 C/T cg06238570 chr21:40685208 BRWD1 -0.61 -6.42 -0.5 2.6e-9 Menarche (age at onset); TGCT cis rs1014246 0.541 rs2011695 chr10:118507219 A/C cg14919929 chr10:118506882 NA -0.38 -6.07 -0.48 1.46e-8 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9291683 0.595 rs11731110 chr4:10037346 T/C cg00071950 chr4:10020882 SLC2A9 0.68 8.83 0.62 8.22e-15 Bone mineral density; TGCT cis rs651907 0.514 rs11706494 chr3:101509475 A/T cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs727505 0.607 rs59635547 chr7:124796371 A/C cg23710748 chr7:124431027 NA -0.26 -4.51 -0.38 1.47e-5 Lewy body disease; TGCT cis rs9926296 0.712 rs459920 chr16:89730827 T/C cg26513180 chr16:89883248 FANCA -0.67 -6.37 -0.5 3.32e-9 Vitiligo; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg02953382 chr22:24373134 LOC391322 -0.82 -9.18 -0.64 1.21e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT trans rs72913475 0.579 rs112653862 chr18:44177859 G/A cg26433034 chr7:128430626 CCDC136 0.61 6.63 0.51 9.33e-10 Midgestational circulating levels of PBDEs (fetal genetic effect); TGCT cis rs11126435 0.844 rs363691 chr2:74841569 C/T cg19285774 chr2:74907978 SEMA4F 0.24 4.59 0.38 1.08e-5 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg00024416 chr22:24240387 NA -0.25 -4.76 -0.39 5.27e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs1005277 0.541 rs2505193 chr10:38394638 G/C cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs12549025 0.516 rs13257250 chr8:23342959 G/A cg00472375 chr8:23315376 ENTPD4 0.71 5.42 0.44 2.98e-7 Reticulocyte fraction of red cells; TGCT cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs1933488 0.898 rs1971152 chr6:153425244 G/C cg24028809 chr6:153414101 RGS17 0.21 4.69 0.39 7.12e-6 Prostate cancer; TGCT cis rs17376456 0.825 rs35496867 chr5:93220400 T/C cg21475434 chr5:93447410 FAM172A 0.7 4.9 0.4 2.96e-6 Diabetic retinopathy; TGCT cis rs9296092 0.538 rs75501442 chr6:33519493 A/G cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT trans rs7613875 0.578 rs2624822 chr3:50107219 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg22535103 chr8:58192502 C8orf71 0.42 4.79 0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs4595586 0.545 rs9668716 chr12:39378833 G/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg10802521 chr3:52805072 NEK4 -0.7 -8.52 -0.61 4.47e-14 Bipolar disorder; TGCT cis rs4819052 0.851 rs8130285 chr21:46671701 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs832540 0.564 rs33329 chr5:56145068 T/C cg24531977 chr5:56204891 C5orf35 -0.54 -5.34 -0.43 4.33e-7 Coronary artery disease; TGCT cis rs11696501 0.694 rs7266372 chr20:44266635 T/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs13040088 0.518 rs2427452 chr20:61577275 T/C cg23096297 chr20:61557774 DIDO1 -0.8 -6.36 -0.5 3.56e-9 Menopause (age at onset); TGCT cis rs7819412 0.668 rs2409714 chr8:11010118 A/G cg03192020 chr8:11204681 TDH -0.53 -4.82 -0.4 4.16e-6 Triglycerides; TGCT cis rs2070488 0.896 rs11914389 chr3:38527215 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.89 9.01 0.63 3.09e-15 Electrocardiographic conduction measures; TGCT cis rs6088580 0.601 rs6120668 chr20:33099793 A/G cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs28595532 0.841 rs114155681 chr4:119736427 A/G cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.29 -0.43 5.34e-7 Developmental language disorder (linguistic errors); TGCT cis rs10791097 0.547 rs11222371 chr11:130745719 C/T cg12179176 chr11:130786555 SNX19 0.85 10.17 0.67 4.79e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4919694 1.000 rs11191445 chr10:104651055 C/T cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs4478858 0.709 rs937786 chr1:31857869 G/A cg07478791 chr1:31886160 SERINC2 0.48 4.76 0.39 5.31e-6 Alcohol dependence; TGCT cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg22920501 chr2:26401640 FAM59B -0.79 -6.23 -0.49 6.63e-9 Gut microbiome composition (summer); TGCT cis rs669446 0.533 rs3791042 chr1:44219275 T/C cg12908607 chr1:44402522 ARTN -0.63 -7.47 -0.56 1.25e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs2562456 0.876 rs2681370 chr19:21736838 T/C cg25650185 chr19:21324782 ZNF431 -0.64 -5.73 -0.46 7.12e-8 Pain; TGCT trans rs2688608 0.587 rs2894040 chr10:75478159 A/C cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs3784262 0.692 rs1822205 chr15:58284657 C/A cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.41 -0.5 2.79e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2760061 0.626 rs2313118 chr1:228118084 T/C cg02753203 chr1:228287806 NA -0.34 -6.57 -0.51 1.24e-9 Diastolic blood pressure; TGCT cis rs6681544 0.544 rs17470277 chr1:82393105 A/C cg04226724 chr1:82268649 LPHN2 0.47 4.99 0.41 2.02e-6 Metabolite levels (X-11787); TGCT cis rs797680 0.964 rs4847398 chr1:93578402 C/T cg17826107 chr1:92977322 EVI5 -0.22 -5.04 -0.41 1.59e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg02073558 chr3:44770973 ZNF501 0.56 5.48 0.44 2.25e-7 Depressive symptoms; TGCT cis rs7937682 0.632 rs11214029 chr11:111761230 C/T cg09085632 chr11:111637200 PPP2R1B 0.8 6.72 0.52 5.79e-10 Primary sclerosing cholangitis; TGCT cis rs9952991 0.941 rs60735058 chr18:12795470 T/A cg24737193 chr18:12778029 NA -0.52 -5.44 -0.44 2.71e-7 Inflammatory skin disease; TGCT cis rs886427 0.591 rs57768809 chr16:3003947 G/A cg05630773 chr16:3016717 KREMEN2 0.31 4.52 0.38 1.42e-5 Metabolic syndrome; TGCT cis rs56104184 0.723 rs73063524 chr19:49409004 T/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs8013055 0.796 rs4074937 chr14:106000977 A/G cg19700328 chr14:106028568 NA -0.5 -5.78 -0.46 5.62e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT trans rs916888 0.773 rs169201 chr17:44790203 A/G cg01341218 chr17:43662625 NA 1.04 7.82 0.57 1.97e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12780845 0.540 rs11254411 chr10:17201701 A/G cg01003015 chr10:17271136 VIM -0.52 -4.71 -0.39 6.42e-6 Homocysteine levels; TGCT cis rs10875595 0.836 rs10062604 chr5:140661932 T/C cg24830062 chr5:140700576 TAF7 -0.6 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs12477438 0.520 rs11123761 chr2:99705903 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs4819052 0.766 rs4819035 chr21:46645715 A/C cg06618935 chr21:46677482 NA -0.35 -4.46 -0.37 1.82e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11783469 0.522 rs11781808 chr8:23256905 G/A cg00472375 chr8:23315376 ENTPD4 0.7 5.6 0.45 1.32e-7 Reticulocyte count; TGCT cis rs62244186 0.715 rs11130032 chr3:44704083 G/A cg09333631 chr3:44802604 KIF15;KIAA1143 -0.42 -4.61 -0.38 9.96e-6 Depressive symptoms; TGCT cis rs7394190 0.748 rs78985317 chr10:75514465 C/T cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.44e-6 Incident atrial fibrillation; TGCT cis rs6964587 0.626 rs1011372 chr7:91509867 T/C cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs3087591 0.919 rs9913470 chr17:29566575 A/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.43 -0.56 1.53e-11 Hip circumference; TGCT cis rs42648 0.569 rs110360 chr7:89856608 C/T cg25739043 chr7:89950458 NA -0.5 -4.83 -0.4 3.91e-6 Homocysteine levels; TGCT cis rs755249 0.727 rs2242500 chr1:40037902 A/G cg19494946 chr1:39956641 BMP8A -0.24 -4.52 -0.38 1.43e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7819412 0.594 rs17724226 chr8:10968926 C/T cg03192020 chr8:11204681 TDH -0.48 -4.57 -0.38 1.19e-5 Triglycerides; TGCT cis rs13118159 0.550 rs28733902 chr4:1374789 A/G cg02018176 chr4:1364513 KIAA1530 0.27 4.57 0.38 1.18e-5 Longevity; TGCT cis rs922182 0.613 rs4238401 chr15:64233110 C/T cg02919090 chr15:64263738 DAPK2 -0.33 -6.14 -0.48 1.05e-8 Blood protein levels; TGCT cis rs13191362 0.507 rs2023036 chr6:163122736 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.61 5.67 0.45 9.31e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6121246 0.697 rs6088857 chr20:30226764 G/C cg21427119 chr20:30132790 HM13 -0.37 -5.19 -0.42 8.51e-7 Mean corpuscular hemoglobin; TGCT cis rs7617480 0.544 rs6442129 chr3:48735256 T/C cg07636037 chr3:49044803 WDR6 0.77 6.37 0.5 3.33e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs10464366 0.746 rs4723822 chr7:39141613 C/T cg18850127 chr7:39170497 POU6F2 0.27 5.7 0.46 8.11e-8 IgG glycosylation; TGCT cis rs10791323 0.569 rs11533204 chr11:133743644 A/G cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs17001868 0.568 rs55769635 chr22:40790101 G/A cg07138101 chr22:40742427 ADSL 0.73 5.6 0.45 1.34e-7 Mammographic density (dense area); TGCT cis rs11190604 0.767 rs3750723 chr10:102172989 T/C cg16005271 chr10:102321736 NA 0.45 4.57 0.38 1.15e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7552404 0.731 rs1493367 chr1:76344011 C/A cg22875332 chr1:76189707 ACADM -0.68 -7.11 -0.54 7.96e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs860295 0.580 rs7528441 chr1:155843256 T/G cg05700447 chr1:155978627 NA 0.21 4.46 0.37 1.8e-5 Body mass index; TGCT cis rs7614311 0.681 rs6801346 chr3:63947128 A/G cg22134162 chr3:63841271 THOC7 0.46 6.03 0.48 1.77e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs908922 0.676 rs945788 chr1:152512762 A/G cg20991723 chr1:152506922 NA 0.42 5.58 0.45 1.42e-7 Hair morphology; TGCT cis rs55962025 0.842 rs362306 chr4:3242100 C/T cg06533319 chr4:3265114 C4orf44 0.23 4.55 0.38 1.27e-5 Parental longevity (mother's age at death); TGCT cis rs1799949 1.000 rs4792981 chr17:41308274 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs9296092 0.560 rs3846853 chr6:33528194 C/G cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2249625 0.508 rs60020363 chr6:72844706 C/T cg24401219 chr6:72892597 RIMS1 0.57 4.46 0.37 1.84e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs7193541 0.684 rs9931225 chr16:74699293 T/C cg01733217 chr16:74700730 RFWD3 1.01 13.9 0.78 4.67e-27 Multiple myeloma; TGCT cis rs7208859 0.673 rs2269915 chr17:29233344 C/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28386778 0.669 rs12603821 chr17:62006432 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.5 -4.78 -0.39 4.81e-6 Prudent dietary pattern; TGCT cis rs2180341 0.618 rs11961994 chr6:127649350 A/G cg27446573 chr6:127587934 RNF146 -0.61 -5.53 -0.44 1.83e-7 Breast cancer; TGCT cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.46e-9 Electroencephalogram traits; TGCT cis rs17030434 0.906 rs12643219 chr4:154670798 T/C cg14289246 chr4:154710475 SFRP2 -0.88 -7.18 -0.54 5.68e-11 Electrocardiographic conduction measures; TGCT cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg13695892 chr22:41940480 POLR3H -0.9 -9.03 -0.63 2.7e-15 Vitiligo; TGCT cis rs7043114 0.525 rs6479416 chr9:95053871 G/T cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.95e-5 Height; TGCT cis rs6667605 0.506 rs10797440 chr1:2541269 A/G cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs9300255 0.602 rs4372492 chr12:123697357 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs908922 0.628 rs488393 chr1:152489548 C/T cg20991723 chr1:152506922 NA 0.48 6.68 0.51 7.17e-10 Hair morphology; TGCT cis rs986417 0.901 rs12436953 chr14:61001546 C/T cg27398547 chr14:60952738 C14orf39 1.38 10.8 0.7 1.4e-19 Gut microbiota (bacterial taxa); TGCT cis rs4566357 0.930 rs12621916 chr2:227923564 T/C cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT trans rs931812 0.895 rs7831714 chr8:101913987 C/T cg20993868 chr7:22813445 NA 0.4 8.7 0.62 1.66e-14 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg24846343 chr22:24311635 DDTL 0.21 5.49 0.44 2.22e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9916302 0.904 rs4794813 chr17:37670994 A/T cg15445000 chr17:37608096 MED1 0.33 4.93 0.4 2.59e-6 Glomerular filtration rate (creatinine); TGCT cis rs1552244 0.882 rs36006511 chr3:10054191 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs2933343 1.000 rs1683782 chr3:128640277 A/G cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs9926296 0.712 rs2434872 chr16:89716915 C/G cg04287289 chr16:89883240 FANCA -0.55 -5.06 -0.41 1.48e-6 Vitiligo; TGCT cis rs11741688 0.557 rs6898923 chr5:178330559 C/T cg09339527 chr5:178322752 ZFP2 -0.29 -4.85 -0.4 3.57e-6 Sleep duration; TGCT cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg03264133 chr6:25882463 NA -1.07 -14.31 -0.79 5.01e-28 Urate levels; TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs9914988 0.943 rs11652272 chr17:27167973 C/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs6088580 0.634 rs6088483 chr20:32984714 T/A cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs3796352 1.000 rs36090694 chr3:53010742 T/C cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6049375 1.000 rs6049366 chr20:24045580 T/C cg14741141 chr20:24973699 C20orf3 0.87 4.96 0.41 2.31e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs7617773 0.779 rs77957078 chr3:48331286 G/C cg11946769 chr3:48343235 NME6 0.79 6.8 0.52 3.97e-10 Coronary artery disease; TGCT cis rs7918232 0.830 rs7087033 chr10:27392522 A/G cg14442939 chr10:27389572 ANKRD26 0.72 5.4 0.44 3.3e-7 Breast cancer; TGCT cis rs916888 0.610 rs199529 chr17:44837217 A/C cg17911788 chr17:44343683 NA -0.59 -6.18 -0.49 8.36e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9952991 0.941 rs2542149 chr18:12779018 G/A cg24737193 chr18:12778029 NA 0.54 6.03 0.48 1.76e-8 Inflammatory skin disease; TGCT cis rs9914544 0.545 rs4924945 chr17:18813160 A/G cg26378065 chr17:18585709 ZNF286B 0.51 4.48 0.37 1.66e-5 Educational attainment (years of education); TGCT cis rs9325144 0.723 rs11169482 chr12:39164327 A/T cg13010199 chr12:38710504 ALG10B 0.51 4.72 0.39 6.28e-6 Morning vs. evening chronotype; TGCT cis rs752010 0.574 rs10890161 chr1:42121623 T/C cg06885757 chr1:42089581 HIVEP3 0.24 4.56 0.38 1.21e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs78456975 1.000 rs10205916 chr2:1558451 A/T cg01028140 chr2:1542097 TPO 0.33 4.53 0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs6754311 0.731 rs10207652 chr2:136588478 T/A cg07169764 chr2:136633963 MCM6 -0.61 -5.69 -0.46 8.62e-8 Mosquito bite size; TGCT cis rs11105298 0.891 rs11105313 chr12:89923376 A/T cg08166232 chr12:89918718 WDR51B;GALNT4 0.66 4.78 0.39 4.85e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2820315 1.000 rs8024 chr1:201845575 C/A cg12730843 chr1:201915899 LMOD1 -0.27 -4.81 -0.4 4.25e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.76 0.46 6.35e-8 Height; TGCT cis rs11235843 0.636 rs2140892 chr11:73422879 A/G cg18195628 chr11:73498948 MRPL48 -0.64 -4.46 -0.37 1.8e-5 Hand grip strength; TGCT cis rs1799949 1.000 rs4793229 chr17:41418334 C/T cg23758822 chr17:41437982 NA -0.7 -6.6 -0.51 1.1e-9 Menopause (age at onset); TGCT cis rs2729354 1.000 rs2848630 chr11:57356907 T/C cg24343310 chr11:57249947 NA 0.28 4.8 0.4 4.5e-6 Blood protein levels; TGCT cis rs2153535 0.580 rs6597332 chr6:8504748 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7647973 0.626 rs62262722 chr3:49769419 G/C cg03060546 chr3:49711283 APEH -0.59 -4.93 -0.41 2.54e-6 Menarche (age at onset); TGCT cis rs7208859 0.623 rs122898 chr17:28905254 C/T cg14008862 chr17:28927542 LRRC37B2 -0.9 -5.66 -0.45 1.01e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7208859 0.562 rs8078897 chr17:29106257 T/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10883723 0.773 rs715439 chr10:104257809 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg13944838 chr5:179740914 GFPT2 -0.4 -6.29 -0.49 4.87e-9 Height; TGCT cis rs4642101 0.883 rs6810325 chr3:12840934 T/C cg05775895 chr3:12838266 CAND2 0.51 4.75 0.39 5.6e-6 QRS complex (12-leadsum); TGCT cis rs79349575 0.783 rs12601955 chr17:47034420 C/T cg07967210 chr17:47022446 SNF8 0.44 6.15 0.48 9.98e-9 Type 2 diabetes; TGCT cis rs7666738 0.830 rs3857217 chr4:99034347 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10791323 0.593 rs10791329 chr11:133716356 T/C cg15485101 chr11:133734466 NA 0.41 5.18 0.42 8.75e-7 Childhood ear infection; TGCT trans rs9650657 0.524 rs10088408 chr8:10817197 C/T cg06636001 chr8:8085503 FLJ10661 -0.86 -8.43 -0.6 7.52e-14 Neuroticism; TGCT cis rs2066819 1.000 rs35526714 chr12:56634639 G/C cg26714650 chr12:56694279 CS -1.29 -5.72 -0.46 7.49e-8 Psoriasis vulgaris; TGCT cis rs9611519 0.732 rs1883826 chr22:41703428 G/A cg13695892 chr22:41940480 POLR3H -0.67 -6.28 -0.49 5.18e-9 Neuroticism; TGCT cis rs6484504 0.576 rs208093 chr11:31184400 C/T cg26647111 chr11:31128758 NA 0.4 5.29 0.43 5.38e-7 Red blood cell count; TGCT cis rs2191566 1.000 rs2356549 chr19:44511202 A/T cg03039196 chr19:44506973 ZNF230 0.55 4.72 0.39 6.23e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs3796352 1.000 rs61172708 chr3:52996052 T/G cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4460629 0.742 rs11581730 chr1:155082158 A/T cg23973274 chr1:155060172 NA -0.26 -4.72 -0.39 6.25e-6 Serum magnesium levels; TGCT cis rs7829975 0.846 rs7005216 chr8:8547110 C/G cg08975724 chr8:8085496 FLJ10661 -0.54 -4.64 -0.38 8.81e-6 Mood instability; TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg01802117 chr1:53393560 SCP2 -0.4 -4.72 -0.39 6.33e-6 Monocyte count; TGCT cis rs73198271 0.773 rs66618176 chr8:8646974 G/C cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs17445774 1.000 rs1509833 chr2:200865225 G/A cg17644776 chr2:200775616 C2orf69 0.32 5.24 0.43 6.69e-7 LDL cholesterol to HDL cholesterol ratio; TGCT cis rs9467773 0.869 rs1796521 chr6:26421392 T/C cg09904177 chr6:26538194 HMGN4 -0.5 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis); TGCT cis rs5769765 0.955 rs8139758 chr22:50261123 G/T cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs4665809 1.000 rs2289022 chr2:26350136 G/T cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs7659604 0.502 rs10013916 chr4:122702179 T/G cg19748678 chr4:122722346 EXOSC9 -0.59 -5.85 -0.47 4.02e-8 Type 2 diabetes; TGCT trans rs2727020 0.729 rs7924782 chr11:49267249 A/G cg03929089 chr4:120376271 NA -0.78 -9.21 -0.64 9.98e-16 Coronary artery disease; TGCT cis rs10540 0.730 rs61877766 chr11:512973 T/G cg03934478 chr11:495069 RNH1 0.32 4.82 0.4 4.16e-6 Body mass index; TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg10108389 chr3:44770937 ZNF501 -0.49 -4.97 -0.41 2.18e-6 Depressive symptoms; TGCT cis rs6845621 0.727 rs11933300 chr4:18896653 A/G cg12196642 chr4:18937545 NA -0.25 -4.52 -0.38 1.45e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg21963583 chr11:68658836 MRPL21 0.38 6.4 0.5 2.84e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2070488 0.636 rs2284817 chr3:38510388 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.65 5.11 0.42 1.19e-6 Electrocardiographic conduction measures; TGCT cis rs11792861 0.926 rs1333344 chr9:111776224 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.48 0.37 1.67e-5 Menarche (age at onset); TGCT cis rs17345786 0.798 rs9817043 chr3:101281852 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.63 6.03 0.48 1.71e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2180341 0.814 rs9401959 chr6:127736464 T/C cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs2354432 0.607 rs894471 chr1:146687913 A/G cg25205988 chr1:146714368 CHD1L -1.23 -5.96 -0.47 2.43e-8 Mitochondrial DNA levels; TGCT cis rs9486719 0.857 rs9285393 chr6:97020917 C/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.72 -0.46 7.69e-8 Migraine;Coronary artery disease; TGCT cis rs7572733 0.515 rs6752458 chr2:198835106 G/T cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs7681440 0.967 rs6532191 chr4:90745930 C/T cg26578617 chr4:90757533 SNCA -0.47 -4.83 -0.4 3.9e-6 Dementia with Lewy bodies; TGCT cis rs559928 0.553 rs508326 chr11:64176029 C/T cg12453748 chr11:64085041 PRDX5;TRMT112 -0.55 -4.78 -0.39 4.9100000000000004e-06 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs875971 1.000 rs9986696 chr7:65704576 C/A cg11764359 chr7:65958608 NA -0.62 -5.54 -0.45 1.76e-7 Aortic root size; TGCT cis rs13191362 1.000 rs7769686 chr6:163199467 A/G cg21926612 chr6:163149169 PACRG;PARK2 1.12 8.19 0.59 2.72e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28699126 0.504 rs1056632 chr2:26512733 T/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Mean corpuscular hemoglobin; TGCT cis rs9303401 0.614 rs3087762 chr17:56568680 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.22 0.49 6.83e-9 Cognitive test performance; TGCT cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs11191270 0.554 rs10444022 chr10:104084889 A/G cg15320455 chr10:103880129 LDB1 0.86 5.39 0.44 3.48e-7 Intelligence (multi-trait analysis); TGCT cis rs41271951 0.512 rs11204774 chr1:151062957 C/T cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg21226059 chr5:178986404 RUFY1 -0.62 -7.37 -0.55 2.14e-11 Lung cancer; TGCT cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs137699 0.604 rs137702 chr22:39750158 T/C cg11247378 chr22:39784982 NA -0.61 -6.01 -0.48 1.9e-8 IgG glycosylation; TGCT cis rs1365505 0.600 rs4238381 chr15:50484714 A/T cg26188685 chr15:50540269 HDC 0.35 6.19 0.49 7.98e-9 Blood metabolite ratios; TGCT cis rs453301 0.686 rs11785819 chr8:8870378 T/G cg11995313 chr8:8860691 ERI1 0.51 4.46 0.37 1.84e-5 Joint mobility (Beighton score); TGCT cis rs7826238 0.720 rs12546760 chr8:8374836 A/G cg15556689 chr8:8085844 FLJ10661 -0.6 -5.35 -0.43 4.04e-7 Systolic blood pressure; TGCT cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg17554472 chr22:41940697 POLR3H -0.48 -5.15 -0.42 9.89e-7 Vitiligo; TGCT cis rs11250464 0.833 rs4554799 chr10:1407728 C/T cg20648369 chr10:1411072 ADARB2 -0.32 -4.49 -0.37 1.59e-5 Radiation response; TGCT cis rs763014 0.898 rs4984897 chr16:632180 G/C cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs950776 0.642 rs34694149 chr15:78965917 C/T cg21242079 chr15:79101063 ADAMTS7 -0.31 -4.71 -0.39 6.54e-6 Sudden cardiac arrest; TGCT cis rs7945705 0.902 rs10769980 chr11:9014180 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.48 5.31 0.43 4.95e-7 Hemoglobin concentration; TGCT cis rs2204008 0.840 rs3892363 chr12:38479487 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Bladder cancer; TGCT cis rs4253772 0.513 rs9306512 chr22:46716603 T/C cg24881330 chr22:46731750 TRMU 0.97 6.37 0.5 3.32e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs765787 0.530 rs4238377 chr15:45541981 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs1843834 0.611 rs1058360 chr2:225449242 A/T cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs7926906 1.000 rs10741374 chr11:90521749 C/T cg26138821 chr11:89956704 CHORDC1 -0.51 -5.52 -0.44 1.92e-7 Intelligence (multi-trait analysis); TGCT cis rs9660180 0.836 rs12038134 chr1:1703865 T/A cg20999797 chr1:1681921 NA 0.18 4.77 0.39 5e-6 Body mass index; TGCT cis rs6860806 0.507 rs200837 chr5:131699958 G/A cg24060327 chr5:131705240 SLC22A5 -0.77 -8.47 -0.61 6.11e-14 Breast cancer; TGCT cis rs796364 1.000 rs1704186 chr2:200769539 A/C cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs425277 0.585 rs3107156 chr1:2060630 T/C cg24578937 chr1:2090814 PRKCZ -0.26 -6.31 -0.49 4.4e-9 Height; TGCT cis rs6867913 0.709 rs891987 chr5:141467196 A/T cg24830494 chr5:140474986 PCDHB2 0.4 4.58 0.38 1.14e-5 Asthma; TGCT cis rs4319547 1.000 rs7307735 chr12:123087442 A/G cg23029597 chr12:123009494 RSRC2 -0.3 -4.88 -0.4 3.14e-6 Body mass index; TGCT cis rs35160687 0.901 rs10520415 chr2:86498738 C/T cg03171300 chr2:86307199 POLR1A -0.32 -5.53 -0.44 1.83e-7 Night sleep phenotypes; TGCT trans rs7618501 0.699 rs9821675 chr3:49902544 A/G cg21659725 chr3:3221576 CRBN 0.78 9.37 0.64 4.19e-16 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.867 rs2470134 chr15:43849886 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.96 -6.6 -0.51 1.06e-9 Lung cancer in ever smokers; TGCT cis rs6570726 0.846 rs1935616 chr6:145943512 C/T cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.647 rs4365346 chr17:17989373 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.68 7.01 0.53 1.33e-10 Total body bone mineral density; TGCT trans rs1908814 0.516 rs4841641 chr8:11798227 G/A cg15556689 chr8:8085844 FLJ10661 0.75 7.07 0.54 9.74e-11 Neuroticism; TGCT cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg07424592 chr7:64974309 NA 1.27 7.86 0.58 1.61e-12 Diabetic kidney disease; TGCT cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg11375102 chr16:1583810 IFT140;TMEM204 -0.31 -5.53 -0.44 1.84e-7 Coronary artery disease; TGCT cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs62064224 0.702 rs735555 chr17:30817450 A/G cg25809561 chr17:30822961 MYO1D -0.27 -4.59 -0.38 1.08e-5 Schizophrenia; TGCT cis rs9653442 0.564 rs12992234 chr2:100767886 G/A cg07810366 chr2:100720526 AFF3 -0.35 -5.26 -0.43 6e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs750474 chr3:53085280 A/C cg07884673 chr3:53033167 SFMBT1 0.55 6.0 0.47 1.97e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1215050 0.547 rs35000521 chr4:98626371 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6735179 0.648 rs10469992 chr2:1760091 A/G cg08534653 chr2:1747700 PXDN -0.56 -4.67 -0.39 7.58e-6 Response to antipsychotic treatment; TGCT cis rs7772486 0.701 rs11155438 chr6:145950112 C/G cg05347473 chr6:146136440 FBXO30 0.53 4.97 0.41 2.2e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg03452623 chr4:187889614 NA -0.36 -5.19 -0.42 8.48e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs11671005 0.735 rs3826684 chr19:58918705 T/C cg13877915 chr19:58951672 ZNF132 0.63 4.92 0.4 2.74e-6 Mean platelet volume; TGCT cis rs3847687 1.000 rs11061290 chr12:131518747 C/T cg25772418 chr12:131519998 GPR133 -0.32 -5.47 -0.44 2.34e-7 Longevity; TGCT cis rs79349575 0.783 rs15563 chr17:47005193 A/G cg26022315 chr17:47021804 SNF8 0.5 4.96 0.41 2.25e-6 Type 2 diabetes; TGCT cis rs11971779 0.941 rs1127424 chr7:139107660 A/G cg07862535 chr7:139043722 LUC7L2 0.79 5.8 0.46 5.13e-8 Diisocyanate-induced asthma; TGCT cis rs7772486 0.840 rs2777478 chr6:146309117 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.0 0.41 1.91e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs8032315 1.000 rs6227 chr15:91425232 C/T cg04510874 chr15:91427884 FES 0.48 5.17 0.42 9.21e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs860295 0.580 rs867548 chr1:155880008 G/C cg13795986 chr1:155880507 RIT1 0.38 4.59 0.38 1.05e-5 Body mass index; TGCT cis rs3845702 1.000 rs259808 chr2:180791419 T/G cg01881094 chr2:180872142 CWC22 -0.68 -5.99 -0.47 2.15e-8 Schizophrenia; TGCT cis rs1577917 1.000 rs12213149 chr6:86668644 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs12711979 0.692 rs6751947 chr2:3820739 G/A cg17052675 chr2:3827356 NA -0.4 -7.82 -0.57 2.02e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs2361710 0.669 rs12940486 chr17:78118569 T/C cg09238746 chr17:78121135 EIF4A3 -0.79 -7.49 -0.56 1.13e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs7010267 0.551 rs6469801 chr8:120025675 T/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs1997103 0.954 rs4947505 chr7:55409448 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7213347 0.780 rs216224 chr17:2156285 T/C cg20777128 chr17:1945076 DPH1;OVCA2 0.53 4.86 0.4 3.5e-6 Total body bone mineral density; TGCT cis rs6089584 0.566 rs2181589 chr20:60622817 C/T cg06108461 chr20:60628389 TAF4 0.43 5.46 0.44 2.54e-7 Body mass index; TGCT cis rs10751667 0.961 rs6597954 chr11:987677 G/A cg06064525 chr11:970664 AP2A2 -0.31 -6.16 -0.48 9.52e-9 Alzheimer's disease (late onset); TGCT cis rs2933343 1.000 rs2933343 chr3:128658492 G/A cg11901034 chr3:128598214 ACAD9 -0.62 -5.0 -0.41 1.92e-6 IgG glycosylation; TGCT cis rs362272 0.524 rs2857982 chr4:3358665 G/A cg22655196 chr4:3374909 RGS12 0.22 4.45 0.37 1.86e-5 Serum sulfate level; TGCT cis rs7772486 0.902 rs1125462 chr6:146417832 A/G cg05347473 chr6:146136440 FBXO30 0.55 5.27 0.43 5.86e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs12541335 0.639 rs3923433 chr8:22169798 A/T cg26039829 chr8:22132926 PIWIL2 0.27 5.07 0.41 1.39e-6 Hypertriglyceridemia; TGCT cis rs9372498 0.536 rs62421536 chr6:118727972 G/A cg07617317 chr6:118971624 C6orf204 0.49 5.27 0.43 5.82e-7 Diastolic blood pressure; TGCT cis rs7752195 0.730 rs2744301 chr6:25323143 G/T cg16898833 chr6:26189333 HIST1H4D 1.16 5.04 0.41 1.62e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs453301 0.686 rs11785634 chr8:8892597 G/T cg06636001 chr8:8085503 FLJ10661 -0.66 -5.58 -0.45 1.42e-7 Joint mobility (Beighton score); TGCT cis rs9467711 1.000 rs9467707 chr6:26327905 G/C cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7089973 0.604 rs7920216 chr10:116611794 G/A cg03647239 chr10:116582469 FAM160B1 0.58 5.49 0.44 2.2e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs3785574 0.582 rs62072238 chr17:61948841 A/T cg11494091 chr17:61959527 GH2 0.45 7.56 0.56 7.84e-12 Height; TGCT cis rs17114671 1.000 rs4982325 chr14:21156836 A/G cg19983597 chr14:21852154 SUPT16H -0.77 -4.49 -0.37 1.58e-5 Blood protein levels; TGCT cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg09174653 chr7:1063357 C7orf50;MIR339 0.23 4.58 0.38 1.11e-5 Longevity;Endometriosis; TGCT cis rs939658 0.805 rs11635757 chr15:79432737 T/C cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs17253792 0.822 rs7150841 chr14:56088986 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.74 0.52 5.33e-10 Electroencephalogram traits; TGCT cis rs7508 0.511 rs208025 chr8:17878170 A/G cg01800426 chr8:17659068 MTUS1 -0.6 -4.88 -0.4 3.21e-6 Atrial fibrillation; TGCT cis rs9650657 0.506 rs7823296 chr8:10778546 A/G cg27411982 chr8:10470053 RP1L1 -0.22 -4.54 -0.38 1.32e-5 Neuroticism; TGCT cis rs8013055 0.706 rs8003957 chr14:105971702 A/G cg25008857 chr14:105974488 NA 0.28 4.52 0.38 1.44e-5 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs6430585 0.702 rs1042712 chr2:136545844 C/G cg07169764 chr2:136633963 MCM6 -1.19 -11.11 -0.71 2.49e-20 Corneal structure; TGCT cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg06238570 chr21:40685208 BRWD1 0.7 6.45 0.5 2.3e-9 Cognitive function; TGCT cis rs2836974 0.897 rs34035316 chr21:40594023 T/C cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.67e-16 Cognitive function; TGCT cis rs864537 0.676 rs2056626 chr1:167420425 T/G cg22356347 chr1:167427500 CD247 -0.21 -5.34 -0.43 4.26e-7 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs2839186 0.869 rs17176513 chr21:47682428 A/G cg13732083 chr21:47605072 C21orf56 0.36 4.63 0.38 9.03e-6 Testicular germ cell tumor; TGCT cis rs7552404 0.731 rs1493367 chr1:76344011 C/A cg03433033 chr1:76189801 ACADM -0.76 -7.76 -0.57 2.66e-12 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs4650994 0.524 rs1998544 chr1:178605276 T/C cg05059571 chr16:84539110 KIAA1609 0.52 10.29 0.68 2.48e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs9325144 0.560 rs2387924 chr12:38662883 A/G cg26384229 chr12:38710491 ALG10B -0.63 -5.92 -0.47 2.9e-8 Morning vs. evening chronotype; TGCT cis rs797680 0.664 rs4847420 chr1:93845674 A/C cg17826107 chr1:92977322 EVI5 -0.23 -5.48 -0.44 2.25e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9902453 0.765 rs12601647 chr17:28164953 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 7.95 0.58 9.99e-13 Coffee consumption (cups per day); TGCT cis rs2836950 0.520 rs11911087 chr21:40665192 G/A cg17971929 chr21:40555470 PSMG1 -0.54 -4.83 -0.4 4e-6 Menarche (age at onset); TGCT cis rs2075371 1.000 rs2598292 chr7:133988584 C/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs1867631 1.000 rs11208927 chr1:67089561 T/C cg13052034 chr1:66999238 SGIP1 0.56 4.75 0.39 5.54e-6 Menopause (age at onset); TGCT cis rs7937682 0.562 rs12275761 chr11:111367083 T/A cg09085632 chr11:111637200 PPP2R1B 0.69 6.53 0.51 1.49e-9 Primary sclerosing cholangitis; TGCT cis rs3096299 0.685 rs4238830 chr16:89540241 C/T cg06640241 chr16:89574553 SPG7 0.77 8.86 0.62 7.12e-15 Multiple myeloma (IgH translocation); TGCT cis rs9467773 0.836 rs1624440 chr6:26433329 G/A cg05738196 chr6:26577821 NA -0.63 -6.86 -0.52 2.91e-10 Intelligence (multi-trait analysis); TGCT cis rs881375 0.934 rs1468671 chr9:123657502 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.55 0.45 1.65e-7 Rheumatoid arthritis; TGCT cis rs2742417 1.000 rs938362 chr3:45746365 T/C cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs56235845 0.694 rs36102285 chr5:176774018 C/T cg06060754 chr5:176797920 RGS14 0.42 6.57 0.51 1.23e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs4689388 0.890 rs4688989 chr4:6290594 T/C cg14416269 chr4:6271139 WFS1 0.37 4.92 0.4 2.69e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg08677398 chr8:58056175 NA 0.33 4.73 0.39 6.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs11250098 0.562 rs6987134 chr8:10804906 T/C cg21775007 chr8:11205619 TDH -0.56 -5.09 -0.42 1.3e-6 Morning vs. evening chronotype; TGCT cis rs11249608 0.548 rs7704565 chr5:178473923 G/C cg21905437 chr5:178450457 ZNF879 0.43 4.49 0.37 1.59e-5 Pubertal anthropometrics; TGCT cis rs1451375 0.698 rs12669770 chr7:50656334 G/A cg18232548 chr7:50535776 DDC 0.44 6.66 0.51 8e-10 Malaria; TGCT cis rs6484504 0.532 rs10835757 chr11:31281902 C/T cg26647111 chr11:31128758 NA -0.35 -4.77 -0.39 5.12e-6 Red blood cell count; TGCT cis rs9393692 0.905 rs6931391 chr6:26279235 G/C cg05868516 chr6:26286170 HIST1H4H 0.63 5.91 0.47 3.02e-8 Educational attainment; TGCT cis rs34526934 0.608 rs7606110 chr2:177028551 T/C cg14324370 chr2:177042789 NA -0.9 -8.57 -0.61 3.41e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs1322512 1.000 rs7744715 chr6:152949026 G/A cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs7119 0.604 rs1055691 chr15:77864625 G/C cg27398640 chr15:77910606 LINGO1 0.25 4.64 0.38 8.6e-6 Type 2 diabetes; TGCT cis rs9467773 1.000 rs6926629 chr6:26499903 T/C cg05738196 chr6:26577821 NA 0.87 12.41 0.74 1.7e-23 Intelligence (multi-trait analysis); TGCT cis rs1729951 0.575 rs747843 chr3:136703130 G/C cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs9346649 0.606 rs7750135 chr6:168490841 C/A cg02770688 chr6:168491649 NA 0.31 5.56 0.45 1.56e-7 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs7772486 0.790 rs2265472 chr6:146220758 G/C cg23711669 chr6:146136114 FBXO30 0.89 10.16 0.67 5.28e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2288884 1.000 rs17779301 chr19:52539243 A/G cg13540795 chr19:52551618 ZNF432 0.56 4.94 0.41 2.5e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs72945132 0.882 rs10466703 chr11:70218548 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.39 0.55 1.94e-11 Coronary artery disease; TGCT cis rs60843830 1.000 rs3791220 chr2:227066 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.74 7.48 0.56 1.19e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9300255 0.739 rs10846491 chr12:123753492 C/G cg00376283 chr12:123451042 ABCB9 0.74 5.71 0.46 7.74e-8 Neutrophil percentage of white cells; TGCT cis rs9926296 0.535 rs36022917 chr16:89893238 A/G cg26513180 chr16:89883248 FANCA 0.72 7.15 0.54 6.73e-11 Vitiligo; TGCT cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg26818010 chr10:134567672 INPP5A -0.37 -5.02 -0.41 1.74e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4654899 0.714 rs12133972 chr1:21091338 A/T cg01072550 chr1:21505969 NA -0.48 -7.17 -0.54 6.05e-11 Superior frontal gyrus grey matter volume; TGCT cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg14983838 chr19:29218262 NA 0.83 6.85 0.52 3.07e-10 Methadone dose in opioid dependence; TGCT cis rs4325129 1.000 rs67371748 chr1:159489964 T/C cg07417683 chr1:159440267 NA -0.46 -4.71 -0.39 6.62e-6 Obesity-related traits; TGCT cis rs13256369 0.802 rs11249888 chr8:8564934 T/C cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs6089829 0.855 rs6090205 chr20:61665269 A/G cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs139371 0.550 rs139348 chr22:39507896 C/T cg18708252 chr22:39545030 CBX7 -0.31 -4.65 -0.39 8.52e-6 Multiple myeloma (IgH translocation);Multiple myeloma (hyperdiploidy); TGCT cis rs2637266 1.000 rs2637267 chr10:78331803 A/G cg18941641 chr10:78392320 NA 0.4 4.98 0.41 2.09e-6 Pulmonary function; TGCT cis rs1799899 0.826 rs8177321 chr3:133473834 G/T cg18342939 chr3:134203408 ANAPC13;CEP63 0.55 5.3 0.43 5.23e-7 Alcohol consumption (transferrin glycosylation); TGCT trans rs2688608 0.839 rs2633311 chr10:75598099 C/T cg13918328 chr10:52500089 ASAH2B -0.69 -6.68 -0.51 7.15e-10 Inflammatory bowel disease; TGCT cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg24549020 chr5:56110836 MAP3K1 0.66 5.79 0.46 5.56e-8 Initial pursuit acceleration; TGCT cis rs78456975 0.689 rs10194040 chr2:1543293 T/G cg01028140 chr2:1542097 TPO -0.37 -5.3 -0.43 5.13e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7772486 0.790 rs3923579 chr6:146230232 C/G cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7017914 0.967 rs13258584 chr8:71671579 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs9534288 0.763 rs34175925 chr13:46611800 G/A cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs2066819 1.000 rs2066819 chr12:56750204 C/T cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9325144 0.600 rs61931871 chr12:38829889 G/A cg10518543 chr12:38710700 ALG10B -0.49 -4.48 -0.37 1.65e-5 Morning vs. evening chronotype; TGCT cis rs6032067 0.636 rs6032092 chr20:43911886 A/C cg16667508 chr20:43936853 MATN4;RBPJL -0.4 -6.56 -0.51 1.32e-9 Blood protein levels; TGCT cis rs28595532 0.920 rs115982145 chr4:119605707 A/G cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.12e-11 Cannabis dependence symptom count; TGCT cis rs6754311 0.552 rs1030765 chr2:136553188 A/T cg07169764 chr2:136633963 MCM6 -0.67 -6.14 -0.48 1.01e-8 Mosquito bite size; TGCT cis rs9677476 1.000 rs13415839 chr2:232126534 C/T cg07929768 chr2:232055508 NA 0.3 4.48 0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs6964587 1.000 rs6969981 chr7:91689461 G/C cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs7582180 0.629 rs12991172 chr2:100941671 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs3862260 0.509 rs1045827 chr1:120162442 C/T cg16322792 chr1:120165303 ZNF697 -0.35 -7.95 -0.58 9.59e-13 Systemic lupus erythematosus; TGCT cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg07092213 chr7:1199455 ZFAND2A -0.43 -4.74 -0.39 5.87e-6 Longevity;Endometriosis; TGCT cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.55 -6.53 -0.51 1.5e-9 Alzheimer's disease; TGCT cis rs6121246 0.559 rs6060716 chr20:30274847 C/G cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg03760483 chr17:6899297 ALOX12 0.48 5.5 0.44 2.11e-7 Tonsillectomy; TGCT cis rs9527 0.525 rs12770034 chr10:104635595 A/G cg04362960 chr10:104952993 NT5C2 0.56 4.77 0.39 5.06e-6 Arsenic metabolism; TGCT trans rs7618501 0.966 rs13063621 chr3:49821625 T/C cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs6032067 0.598 rs2741500 chr20:43944958 G/T cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -6.76 -0.52 4.76e-10 Blood protein levels; TGCT cis rs7412746 0.621 rs11204749 chr1:150929563 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs6500602 0.701 rs4785968 chr16:4535307 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.39 6.86 0.52 2.91e-10 Schizophrenia; TGCT cis rs904251 0.523 rs10947675 chr6:37479972 G/A cg25019722 chr6:37503610 NA -0.52 -7.67 -0.57 4.31e-12 Cognitive performance; TGCT cis rs7178572 0.568 rs11630689 chr15:77520094 C/T cg15453836 chr15:77711506 NA -0.44 -4.92 -0.4 2.67e-6 Type 2 diabetes; TGCT cis rs4711350 0.862 rs652049 chr6:33711420 C/T cg00334056 chr6:33755658 LEMD2 0.31 4.81 0.4 4.31e-6 Schizophrenia; TGCT trans rs5771242 0.518 rs5771258 chr22:50675648 C/A cg26607758 chr8:91997553 NA 0.69 6.87 0.53 2.76e-10 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs12510870 0.599 rs28693538 chr4:74450490 T/G cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs9549260 0.755 rs9532577 chr13:41231542 A/G cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs17401966 0.931 rs12137880 chr1:10388620 T/C cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs10504229 0.906 rs56130194 chr8:58197061 C/A cg08280861 chr8:58055591 NA 0.36 4.67 0.39 7.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs1729951 0.575 rs835642 chr3:136703365 A/T cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs7726839 0.540 rs3749618 chr5:602650 A/G cg09021430 chr5:549028 NA -0.39 -5.26 -0.43 6.14e-7 Obesity-related traits; TGCT cis rs916888 0.773 rs199451 chr17:44801784 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.79 5.34 0.43 4.3e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7017914 0.905 rs3110240 chr8:71930104 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs523522 0.962 rs7136951 chr12:120941927 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs250677 0.652 rs1422582 chr5:148436925 T/C cg23229984 chr5:148520753 ABLIM3 0.22 4.98 0.41 2.05e-6 Breast cancer; TGCT cis rs6570726 0.967 rs403584 chr6:145807010 G/A cg23711669 chr6:146136114 FBXO30 0.67 6.32 0.49 4.31e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10851411 0.817 rs56357092 chr15:42790529 G/A cg23803468 chr15:43513504 EPB42 0.28 5.15 0.42 1.01e-6 Glucose homeostasis traits; TGCT cis rs7258465 0.965 rs8100767 chr19:18589088 T/C cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs10992471 0.756 rs11792342 chr9:95143668 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.31 -0.49 4.46e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4319547 0.697 rs7974262 chr12:122896385 C/T cg08088222 chr12:122070432 ORAI1 -0.25 -4.43 -0.37 2.01e-5 Body mass index; TGCT cis rs7666738 0.830 rs3911282 chr4:99037602 T/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9894429 0.646 rs58398000 chr17:79576923 G/A cg21028142 chr17:79581711 NPLOC4 -0.29 -5.95 -0.47 2.56e-8 Eye color traits; TGCT cis rs514406 0.861 rs7524476 chr1:53240212 C/T cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs4595586 0.545 rs2218762 chr12:39397762 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs3540 0.513 rs2589962 chr15:90921636 G/A cg22089800 chr15:90895588 ZNF774 0.82 9.04 0.63 2.61e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs9660180 0.967 rs12040325 chr1:1702436 G/A cg20999797 chr1:1681921 NA 0.18 4.77 0.39 5.09e-6 Body mass index; TGCT cis rs9467773 0.649 rs2145318 chr6:26496603 T/A cg26531700 chr6:26746687 NA 0.57 5.54 0.45 1.75e-7 Intelligence (multi-trait analysis); TGCT cis rs7914558 1.000 rs943038 chr10:104826261 T/C cg04362960 chr10:104952993 NT5C2 0.59 5.28 0.43 5.56e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6582630 0.555 rs11182217 chr12:38480030 G/A cg26384229 chr12:38710491 ALG10B 0.89 8.05 0.59 5.63e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs9383153 1.000 rs9370887 chr6:16329258 G/C cg20052079 chr6:15504923 JARID2 0.85 4.77 0.39 5.06e-6 Gambling; TGCT cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg04267008 chr7:1944627 MAD1L1 0.35 4.62 0.38 9.36e-6 Bipolar disorder and schizophrenia; TGCT cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Vitiligo; TGCT cis rs12579753 0.709 rs34503239 chr12:82124199 G/T cg07988820 chr12:82153109 PPFIA2 -0.67 -7.13 -0.54 7.12e-11 Resting heart rate; TGCT cis rs2880765 0.835 rs4842886 chr15:86035773 G/A cg13263323 chr15:86062960 AKAP13 -0.22 -4.84 -0.4 3.84e-6 Coronary artery disease; TGCT cis rs797680 0.927 rs1000607 chr1:93772001 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.1 -0.42 1.24e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs3091242 0.933 rs909833 chr1:25754140 C/G cg09222892 chr1:25734099 RHCE -0.43 -7.1 -0.54 8.54e-11 Erythrocyte sedimentation rate; TGCT cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg06481639 chr22:41940642 POLR3H -0.72 -6.29 -0.49 4.98e-9 Vitiligo; TGCT cis rs208520 1.000 rs12191403 chr6:66978137 C/T cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs2535633 0.588 rs2564930 chr3:53017307 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.55 5.24 0.43 6.68e-7 Body mass index; TGCT cis rs7552404 1.000 rs28602663 chr1:76235355 C/T cg22875332 chr1:76189707 ACADM 0.76 8.83 0.62 8.53e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9926296 0.744 rs164749 chr16:89708224 A/C cg26513180 chr16:89883248 FANCA -0.56 -5.49 -0.44 2.19e-7 Vitiligo; TGCT cis rs1008375 1.000 rs28552744 chr4:17620165 A/G cg10189774 chr4:17578691 LAP3 0.6 5.21 0.42 7.64e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg06618935 chr21:46677482 NA -0.37 -5.83 -0.46 4.48e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10256972 0.681 rs12702016 chr7:1129392 C/T cg18765753 chr7:1198926 ZFAND2A -0.48 -5.53 -0.44 1.83e-7 Longevity;Endometriosis; TGCT cis rs477895 1.000 rs12785488 chr11:64107521 G/A cg04317338 chr11:64019027 PLCB3 0.69 5.36 0.43 3.98e-7 Mean platelet volume; TGCT cis rs6688613 0.694 rs2075946 chr1:166818566 A/G cg07049167 chr1:166818506 POGK 0.24 5.09 0.42 1.31e-6 Refractive astigmatism; TGCT cis rs651907 0.535 rs13084113 chr3:101534039 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.43 0.68 1.13e-18 Colorectal cancer; TGCT cis rs2243480 1.000 rs1039664 chr7:65449716 T/G cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg11062466 chr8:58055876 NA 0.37 4.48 0.37 1.65e-5 Developmental language disorder (linguistic errors); TGCT cis rs4372836 0.729 rs12714241 chr2:28969413 T/C cg09522027 chr2:28974177 PPP1CB -0.63 -6.25 -0.49 6.12e-9 Body mass index; TGCT cis rs9583531 0.600 rs9555724 chr13:111354110 C/T cg24331049 chr13:111365604 ING1 -0.74 -7.42 -0.55 1.58e-11 Coronary artery disease; TGCT cis rs2836974 0.799 rs8129303 chr21:40711959 G/A cg11890956 chr21:40555474 PSMG1 1.0 9.38 0.64 3.9e-16 Cognitive function; TGCT cis rs9896933 0.775 rs615630 chr17:80730527 T/C cg20578329 chr17:80767326 TBCD 0.32 4.58 0.38 1.1e-5 Bone mineral accretion in asthma (oral corticosteroid dose interaction); TGCT cis rs6952808 0.692 rs11773316 chr7:2027354 C/T cg22963979 chr7:1858916 MAD1L1 -0.44 -7.18 -0.54 5.77e-11 Bipolar disorder and schizophrenia; TGCT cis rs7589728 0.563 rs80324973 chr2:88447264 T/G cg04511125 chr2:88470314 THNSL2 0.79 6.55 0.51 1.37e-9 Plasma clusterin levels; TGCT cis rs9611565 0.546 rs5758426 chr22:42098763 T/G cg06481639 chr22:41940642 POLR3H 0.6 5.18 0.42 8.77e-7 Vitiligo; TGCT cis rs11018874 0.709 rs10830428 chr11:89894294 C/G cg23743573 chr11:89867420 NAALAD2 -0.4 -4.44 -0.37 2e-5 White blood cell types; TGCT cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg23283495 chr1:209979779 IRF6 0.65 5.53 0.44 1.81e-7 Cleft lip with or without cleft palate; TGCT cis rs40363 0.645 rs4786421 chr16:3522303 A/G cg00484396 chr16:3507460 NAT15 -0.44 -6.59 -0.51 1.12e-9 Tuberculosis; TGCT cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg02353165 chr6:42928485 GNMT 0.94 9.64 0.65 9.69e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs36093844 1.000 rs11234452 chr11:85576801 C/T cg25872744 chr11:85566296 CCDC83 -0.52 -5.09 -0.42 1.31e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs6089829 0.962 rs6062776 chr20:61663736 A/G cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT trans rs77457752 0.525 rs10120716 chr9:13897909 G/A cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.21e-10 Breast cancer; TGCT trans rs7618501 0.602 rs34831713 chr3:50118748 T/C cg21659725 chr3:3221576 CRBN -0.73 -8.48 -0.61 5.64e-14 Intelligence (multi-trait analysis); TGCT cis rs2072499 1.000 rs2072499 chr1:156169610 A/G cg25208724 chr1:156163844 SLC25A44 1.11 16.13 0.82 3.11e-32 Testicular germ cell tumor; TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg26354017 chr1:205819088 PM20D1 0.56 6.81 0.52 3.75e-10 Menarche (age at onset); TGCT cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.39 0.5 3.07e-9 Cognitive function; TGCT trans rs208520 0.690 rs10455594 chr6:66737894 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs2594989 0.887 rs2442797 chr3:11555935 C/T cg00170343 chr3:11313890 ATG7 0.63 4.47 0.37 1.77e-5 Circulating chemerin levels; TGCT cis rs981844 0.712 rs10009854 chr4:154741785 C/T cg14289246 chr4:154710475 SFRP2 -1.0 -9.26 -0.64 7.7e-16 Response to statins (LDL cholesterol change); TGCT cis rs8062405 0.824 rs62034319 chr16:28532188 T/G cg09754948 chr16:28834200 ATXN2L 0.6 4.64 0.38 8.69e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2455799 0.573 rs2455833 chr3:15752830 T/C cg16303742 chr3:15540471 COLQ -0.26 -4.99 -0.41 2.03e-6 Mean platelet volume; TGCT cis rs3087591 0.708 rs12940802 chr17:29643564 C/A cg24425628 chr17:29625626 OMG;NF1 0.41 5.82 0.46 4.76e-8 Hip circumference; TGCT cis rs7666738 0.830 rs6843777 chr4:98866635 T/A cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.99e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9341808 0.667 rs1575541 chr6:80917485 T/A cg08355045 chr6:80787529 NA 0.3 5.05 0.41 1.51e-6 Sitting height ratio; TGCT cis rs35306767 0.671 rs11253473 chr10:906826 A/G cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs698813 0.674 rs6544751 chr2:44495845 A/G cg00619915 chr2:44497795 NA -0.24 -5.41 -0.44 3.11e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT trans rs6089829 0.888 rs4809465 chr20:61671156 G/C cg17470723 chr8:74884337 TCEB1 0.78 6.83 0.52 3.42e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1008375 0.966 rs1476836 chr4:17585014 G/C cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs79149102 0.579 rs74247779 chr15:75397131 G/A cg09165964 chr15:75287851 SCAMP5 -0.92 -4.65 -0.39 8.24e-6 Lung cancer; TGCT cis rs3809566 0.654 rs6494384 chr15:63325607 C/G cg00520135 chr15:63333846 TPM1 -0.41 -5.03 -0.41 1.66e-6 Platelet count; TGCT cis rs9399135 0.967 rs9321481 chr6:135352648 C/G cg24558204 chr6:135376177 HBS1L -0.48 -4.91 -0.4 2.85e-6 Red blood cell count; TGCT cis rs4824093 0.610 rs4141437 chr22:50243719 C/G cg14114931 chr22:50943910 LMF2 -0.36 -4.53 -0.38 1.37e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2235642 0.717 rs2236269 chr16:1652614 T/A cg07639376 chr16:1584516 IFT140;TMEM204 -0.29 -5.03 -0.41 1.66e-6 Coronary artery disease; TGCT cis rs9902453 0.808 rs76515799 chr17:28169491 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs7552404 0.727 rs6678348 chr1:76332463 C/T cg03433033 chr1:76189801 ACADM 0.59 5.95 0.47 2.53e-8 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs1005277 0.540 rs116205409 chr10:38478970 G/A cg27523141 chr10:43048294 ZNF37B 0.73 8.51 0.61 4.68e-14 Extrinsic epigenetic age acceleration; TGCT cis rs12220238 1.000 rs73284257 chr10:76000710 T/G cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.36 0.55 2.18e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4906332 0.811 rs2021965 chr14:103997248 C/A cg26031613 chr14:104095156 KLC1 0.57 4.6 0.38 1.02e-5 Coronary artery disease; TGCT cis rs2204008 0.729 rs114133083 chr12:38182923 G/C cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs9906944 0.707 rs9899931 chr17:47108282 G/A cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7086627 0.515 rs6585994 chr10:82191643 A/G cg00277334 chr10:82204260 NA -0.36 -4.9 -0.4 2.94e-6 Post bronchodilator FEV1; TGCT trans rs4919669 0.719 rs11818043 chr10:104391627 A/G cg24066601 chr6:26271455 HIST1H3G 0.68 6.69 0.51 7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs4953076 0.573 rs2053456 chr2:44448632 G/A cg00619915 chr2:44497795 NA -0.22 -5.05 -0.41 1.52e-6 Height; TGCT cis rs1153858 1.000 rs4271549 chr15:45652730 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs597539 0.690 rs608810 chr11:68624118 G/C cg21963583 chr11:68658836 MRPL21 0.38 6.17 0.48 9.07e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7267979 1.000 rs2500436 chr20:25406366 G/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7100689 0.784 rs1870142 chr10:82182296 G/A cg01528321 chr10:82214614 TSPAN14 0.9 9.42 0.65 3.22e-16 Post bronchodilator FEV1; TGCT cis rs7635838 0.684 rs2606758 chr3:11353064 G/A cg00170343 chr3:11313890 ATG7 0.6 5.86 0.47 3.84e-8 HDL cholesterol; TGCT cis rs35771425 0.572 rs34552796 chr1:211422229 C/T cg25617285 chr1:211431773 RCOR3 -0.46 -5.03 -0.41 1.65e-6 Educational attainment (years of education); TGCT trans rs1499614 0.803 rs1922723 chr7:66175063 C/T cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs79349575 0.715 rs62075844 chr17:47002389 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs2637266 1.000 rs2894337 chr10:78344871 C/T cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT cis rs9486719 0.857 rs2971609 chr6:97039665 A/G cg18709589 chr6:96969512 KIAA0776 -0.78 -6.38 -0.5 3.24e-9 Migraine;Coronary artery disease; TGCT cis rs6912958 0.781 rs3757368 chr6:88224495 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs8014204 0.550 rs2302832 chr14:75137664 T/C cg06637938 chr14:75390232 RPS6KL1 0.64 5.86 0.47 3.82e-8 Caffeine consumption; TGCT cis rs1552244 1.000 rs3895942 chr3:10108745 G/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs1982963 0.613 rs2749885 chr14:52516567 T/G cg10843707 chr14:52510701 NID2 -0.27 -4.64 -0.38 8.72e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9660992 0.542 rs17345153 chr1:205179997 A/G cg03948781 chr1:205179583 DSTYK 0.35 4.53 0.38 1.39e-5 Mean corpuscular volume;Mean platelet volume; TGCT trans rs1005277 0.502 rs2800484 chr10:38542415 C/T cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs2299587 0.689 rs2285303 chr8:17797409 A/G cg01800426 chr8:17659068 MTUS1 -0.65 -5.68 -0.45 9.22e-8 Economic and political preferences; TGCT cis rs4900538 0.855 rs1190537 chr14:102887816 C/T cg18135206 chr14:102964638 TECPR2 -0.2 -4.53 -0.38 1.39e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs651907 0.535 rs58658478 chr3:101511667 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.5 4.61 0.38 1.01e-5 Colorectal cancer; TGCT cis rs6088590 0.523 rs6088536 chr20:33189106 T/C cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs360798 0.532 rs360799 chr2:62953166 G/A cg17519650 chr2:63277830 OTX1 -0.54 -4.64 -0.38 8.69e-6 Coronary artery disease; TGCT cis rs6088580 0.634 rs3746455 chr20:32957216 G/A cg08999081 chr20:33150536 PIGU -0.27 -5.33 -0.43 4.46e-7 Glomerular filtration rate (creatinine); TGCT cis rs1005224 0.889 rs12717566 chr14:76147507 C/T cg25116370 chr14:76127843 TTLL5;C14orf1 -0.57 -4.9 -0.4 2.99e-6 Large artery stroke; TGCT cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg11941060 chr3:133502564 NA -0.31 -6.59 -0.51 1.1e-9 Iron status biomarkers; TGCT cis rs854765 0.583 rs6502627 chr17:17849671 C/T cg09796270 chr17:17721594 SREBF1 0.23 4.45 0.37 1.92e-5 Total body bone mineral density; TGCT cis rs10992471 0.528 rs10820975 chr9:95211922 T/G cg13798575 chr9:95087839 CENPP;NOL8 -0.51 -4.88 -0.4 3.25e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10193935 0.901 rs17029411 chr2:42479149 G/A cg27598129 chr2:42591480 NA -0.37 -5.12 -0.42 1.12e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7727544 0.582 rs3749756 chr5:131534499 C/T cg14196790 chr5:131705035 SLC22A5 0.33 4.49 0.37 1.59e-5 Blood metabolite levels; TGCT cis rs10791323 0.604 rs2723605 chr11:133711241 C/G cg15485101 chr11:133734466 NA 0.39 5.03 0.41 1.71e-6 Childhood ear infection; TGCT cis rs5750830 0.621 rs5750810 chr22:39792943 A/G cg24399712 chr22:39784796 NA -1.08 -12.62 -0.75 5.47e-24 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.69 5.83 0.46 4.5e-8 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.626 rs1996663 chr3:49878264 C/G cg03060546 chr3:49711283 APEH -0.61 -5.27 -0.43 5.75e-7 Menarche (age at onset); TGCT cis rs644799 1.000 rs611020 chr11:95567905 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.88 9.12 0.63 1.65e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs478304 0.619 rs10896028 chr11:65432187 A/T cg17480646 chr11:65405466 SIPA1 -0.63 -8.28 -0.6 1.67e-13 Acne (severe); TGCT cis rs7208859 0.673 rs73277964 chr17:29179201 A/T cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28595532 1.000 rs55634130 chr4:119655093 C/T cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT cis rs6752107 1.000 rs6431654 chr2:234161769 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.86 0.4 3.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs711830 1.000 rs6433571 chr2:177039578 G/T cg13092806 chr2:177043255 NA 0.76 6.11 0.48 1.19e-8 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs9858542 0.953 rs4625 chr3:49572140 A/G cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs9810089 0.843 rs1279086 chr3:136038574 G/A cg12473912 chr3:136751656 NA 0.36 5.15 0.42 9.88e-7 Gestational age at birth (child effect); TGCT cis rs4808199 0.895 rs10419672 chr19:19471241 T/C cg03709012 chr19:19516395 GATAD2A 0.83 6.68 0.51 7.27e-10 Nonalcoholic fatty liver disease; TGCT cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs933688 0.938 rs6866923 chr5:90669352 A/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.03 9.42 0.65 3.21e-16 Smoking behavior; TGCT cis rs6554196 0.654 rs7684939 chr4:55509189 G/A cg02821500 chr4:54931072 CHIC2 0.48 4.57 0.38 1.18e-5 Monocyte count; TGCT cis rs7582180 0.715 rs920270 chr2:100917961 T/C cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.45e-6 Intelligence (multi-trait analysis); TGCT trans rs2727020 0.757 rs7924526 chr11:49267043 G/A cg03929089 chr4:120376271 NA 0.73 8.12 0.59 4e-13 Coronary artery disease; TGCT cis rs931127 0.666 rs7932857 chr11:65457493 A/C cg17480646 chr11:65405466 SIPA1 -0.43 -5.74 -0.46 6.76e-8 Systemic lupus erythematosus; TGCT cis rs600231 0.706 rs11227221 chr11:65319265 T/C cg21890820 chr11:65308645 LTBP3 -0.38 -4.76 -0.39 5.39e-6 Bone mineral density; TGCT cis rs1903068 0.719 rs1380068 chr4:56003707 C/G cg16572876 chr4:56024045 NA 0.41 4.5 0.37 1.56e-5 Endometriosis; TGCT cis rs11017221 0.891 rs7905219 chr10:132162712 C/T cg16316180 chr10:131577011 NA 0.27 4.51 0.38 1.48e-5 Migraine; TGCT cis rs7647973 0.731 rs9831648 chr3:49214303 G/T cg07636037 chr3:49044803 WDR6 0.62 4.67 0.39 7.61e-6 Menarche (age at onset); TGCT cis rs3806843 0.576 rs155361 chr5:140307284 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.43 -5.33 -0.43 4.44e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs17376456 0.825 rs13155452 chr5:93164449 C/T cg25358565 chr5:93447407 FAM172A -0.86 -7.11 -0.54 8e-11 Diabetic retinopathy; TGCT cis rs7726839 0.540 rs3792720 chr5:643028 T/G cg09021430 chr5:549028 NA -0.39 -5.37 -0.43 3.77e-7 Obesity-related traits; TGCT cis rs4805272 0.820 rs10408080 chr19:29341652 T/C cg15000279 chr19:29285009 NA 0.56 6.32 0.49 4.37e-9 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs597539 0.617 rs672853 chr11:68636362 G/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.83 7.86 0.58 1.55e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs727563 0.593 rs132770 chr22:42017264 A/G cg06481639 chr22:41940642 POLR3H 0.73 6.46 0.5 2.13e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1348850 0.958 rs11689550 chr2:178456298 A/G cg22681709 chr2:178499509 PDE11A -0.41 -5.02 -0.41 1.77e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs6964587 1.000 rs36120033 chr7:91679298 G/A cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs1023500 0.573 rs133382 chr22:42471774 C/T cg05082376 chr22:42548792 NA -0.23 -5.43 -0.44 2.83e-7 Schizophrenia; TGCT trans rs17603886 0.686 rs13323090 chr3:10506644 C/T cg13546308 chr3:153366155 NA -0.54 -6.76 -0.52 4.74e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs155076 0.711 rs4770131 chr13:21897468 A/G cg11317459 chr13:21872234 NA 1.38 12.23 0.74 4.74e-23 White matter hyperintensity burden; TGCT cis rs7635838 0.617 rs346085 chr3:11282724 T/C cg00170343 chr3:11313890 ATG7 0.64 6.28 0.49 5.27e-9 HDL cholesterol; TGCT cis rs2361718 0.967 rs12942941 chr17:78103013 C/T cg09238746 chr17:78121135 EIF4A3 -0.52 -4.56 -0.38 1.2e-5 Yeast infection; TGCT cis rs513349 0.964 rs210141 chr6:33546825 T/C cg07679836 chr6:33548423 BAK1 0.31 4.47 0.37 1.77e-5 Platelet count; TGCT cis rs539096 0.830 rs10789435 chr1:44026053 T/G cg12908607 chr1:44402522 ARTN -0.51 -5.28 -0.43 5.57e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs2318147 chr8:58114931 C/T cg02725872 chr8:58115012 NA -0.36 -4.81 -0.4 4.33e-6 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs74745121 chr7:106958037 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs4366490 0.687 rs1954993 chr11:62871896 C/A cg21002970 chr11:62369079 MTA2 0.61 4.46 0.37 1.79e-5 Conotruncal heart defects; TGCT cis rs2797160 0.967 rs1777182 chr6:126013614 T/A cg05901451 chr6:126070800 HEY2 0.74 6.12 0.48 1.15e-8 Endometrial cancer; TGCT cis rs12950390 0.853 rs56363619 chr17:45854621 T/C cg06532163 chr17:45867833 NA 0.35 5.44 0.44 2.76e-7 IgG glycosylation; TGCT cis rs6430585 0.759 rs12467770 chr2:136536095 G/A cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs9674544 0.646 rs6504594 chr17:47142697 C/A cg20966754 chr17:47091339 IGF2BP1 -0.42 -4.95 -0.41 2.35e-6 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs11105298 0.891 rs10506972 chr12:89861529 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1865760 0.516 rs10807007 chr6:26048931 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.39 0.55 1.92e-11 Height; TGCT cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg00814883 chr7:100076585 TSC22D4 -0.82 -8.37 -0.6 1.03e-13 Platelet count; TGCT cis rs7666738 0.830 rs10014986 chr4:99000687 A/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6547741 1.000 rs1919125 chr2:27801403 C/G cg27432699 chr2:27873401 GPN1 0.18 4.64 0.38 8.54e-6 Oral cavity cancer; TGCT cis rs225245 0.791 rs6505492 chr17:34026597 C/T cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs67366981 0.800 rs55939042 chr14:77691186 T/A cg06779847 chr14:77687015 TMEM63C -0.42 -4.54 -0.38 1.33e-5 Obsessive-compulsive symptoms; TGCT cis rs57920188 0.535 rs12129515 chr1:4094101 G/A cg20703997 chr1:4087676 NA 0.48 5.7 0.46 8.27e-8 Interleukin-17 levels; TGCT cis rs9814567 1.000 rs6763088 chr3:134254989 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11098499 0.955 rs1397608 chr4:120161744 A/G cg24670566 chr4:120433619 PDE5A 0.23 4.45 0.37 1.89e-5 Corneal astigmatism; TGCT cis rs11785400 0.793 rs9297972 chr8:143723660 C/T cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs2663905 1.000 rs2663905 chr15:81359137 G/A cg09236163 chr15:81426669 C15orf26 -0.45 -4.61 -0.38 9.83e-6 QT interval (drug interaction); TGCT trans rs9929218 0.529 rs2296404 chr16:68729525 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.54 6.81 0.52 3.78e-10 Colorectal cancer; TGCT cis rs3764628 1.000 rs72997355 chr19:18768709 G/A cg20098710 chr19:19640075 YJEFN3 -0.46 -4.78 -0.39 4.8e-6 Orofacial clefts; TGCT cis rs7226408 0.857 rs34250790 chr18:34447980 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9611565 0.729 rs2413647 chr22:41907148 G/A cg13695892 chr22:41940480 POLR3H -0.91 -8.8 -0.62 9.77e-15 Vitiligo; TGCT cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg16049864 chr8:95962084 TP53INP1 -0.6 -7.11 -0.54 8.27e-11 Type 2 diabetes; TGCT cis rs6964587 0.869 rs10250014 chr7:91490208 T/C cg17063962 chr7:91808500 NA -0.85 -9.05 -0.63 2.54e-15 Breast cancer; TGCT cis rs7843479 0.601 rs4872207 chr8:21842751 C/G cg17168535 chr8:21777572 XPO7 -0.8 -8.06 -0.59 5.48e-13 Mean corpuscular volume; TGCT cis rs7119 0.931 rs62009087 chr15:77833064 C/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.68 -0.39 7.4e-6 Type 2 diabetes; TGCT cis rs4819052 0.851 rs8131143 chr21:46671646 C/G cg06618935 chr21:46677482 NA 0.36 5.44 0.44 2.71e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg11494091 chr17:61959527 GH2 -0.6 -13.07 -0.76 4.44e-25 Prudent dietary pattern; TGCT cis rs911555 0.755 rs12436729 chr14:103929889 G/C cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs72945132 0.882 rs66989619 chr11:70202127 G/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs711245 0.573 rs7570763 chr2:36800589 A/C cg15105969 chr2:36825350 FEZ2 -0.61 -5.71 -0.46 7.72e-8 Height; TGCT cis rs4851266 1.000 rs7566527 chr2:100811970 C/T cg22139774 chr2:100720529 AFF3 -0.34 -4.98 -0.41 2.13e-6 Educational attainment; TGCT cis rs12950390 0.853 rs11655112 chr17:45856563 T/C cg24803719 chr17:45855879 NA -0.5 -5.12 -0.42 1.15e-6 IgG glycosylation; TGCT cis rs826838 0.967 rs4768329 chr12:39129394 T/C cg26384229 chr12:38710491 ALG10B -0.87 -7.78 -0.57 2.42e-12 Heart rate; TGCT cis rs35306767 0.623 rs72760943 chr10:1143104 G/A cg26597838 chr10:835615 NA 0.47 4.95 0.41 2.37e-6 Eosinophil percentage of granulocytes; TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg17178900 chr1:205818956 PM20D1 -0.52 -6.47 -0.5 2.04e-9 Monocyte percentage of white cells; TGCT cis rs4478858 0.709 rs3766296 chr1:31820223 G/A cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs7940866 0.903 rs10750457 chr11:130850277 T/C cg05962950 chr11:130786565 SNX19 0.64 6.36 0.5 3.53e-9 Schizophrenia; TGCT cis rs9653442 0.564 rs4851256 chr2:100775045 A/G cg22139774 chr2:100720529 AFF3 -0.33 -5.34 -0.43 4.25e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs7618501 1.000 rs11130219 chr3:49752427 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT trans rs10435719 0.871 rs7815186 chr8:11792062 C/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs8180040 0.966 rs12632132 chr3:47477019 C/T cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs2153535 0.580 rs1335643 chr6:8488021 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs921968 0.612 rs832810 chr2:219322430 T/C cg02176678 chr2:219576539 TTLL4 0.38 5.51 0.44 1.97e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs2742234 0.955 rs2435385 chr10:43665750 A/G cg02780029 chr10:43622663 RET -0.26 -4.98 -0.41 2.07e-6 Hirschsprung disease; TGCT cis rs7727544 0.684 rs2631363 chr5:131707095 A/G cg24060327 chr5:131705240 SLC22A5 0.62 6.77 0.52 4.69e-10 Blood metabolite levels; TGCT cis rs13064411 0.696 rs1486894 chr3:113211513 G/A cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs56176327 0.583 rs7613603 chr3:49812866 C/T cg03060546 chr3:49711283 APEH -0.63 -5.63 -0.45 1.12e-7 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 6.23 0.49 6.72e-9 Menarche (age at onset); TGCT cis rs2637266 0.690 rs2579730 chr10:78443441 G/T cg18941641 chr10:78392320 NA 0.4 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg27211696 chr2:191398769 TMEM194B -0.27 -5.07 -0.41 1.42e-6 Pulse pressure; TGCT cis rs2249625 0.564 rs2496489 chr6:72877338 G/A cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs631288 0.557 rs920682 chr1:146657523 C/A cg25205988 chr1:146714368 CHD1L 1.34 5.37 0.43 3.79e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg10295955 chr4:187884368 NA -0.99 -15.24 -0.81 3.38e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 0.611 rs6540563 chr1:210019858 C/G cg22029157 chr1:209979665 IRF6 0.71 5.09 0.42 1.3e-6 Cleft lip with or without cleft palate; TGCT cis rs10256972 0.641 rs12702017 chr7:1129413 C/T cg18765753 chr7:1198926 ZFAND2A -0.48 -5.53 -0.44 1.83e-7 Longevity;Endometriosis; TGCT cis rs6459804 0.503 rs2159470 chr7:157506540 G/A cg14168080 chr7:157504135 PTPRN2 -0.4 -4.49 -0.37 1.58e-5 Bipolar disorder and schizophrenia; TGCT cis rs3935685 1.000 rs4886904 chr15:78027178 C/T cg25212270 chr15:78015279 NA 0.32 6.43 0.5 2.54e-9 Intelligence (multi-trait analysis); TGCT trans rs10435719 0.899 rs9329251 chr8:11793606 G/A cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs3947 0.855 rs1296026 chr8:11697442 C/T cg02840367 chr8:11660030 FDFT1 0.91 6.65 0.51 8.45e-10 Blood protein levels; TGCT cis rs7226408 0.857 rs11665085 chr18:34469465 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.88 0.4 3.13e-6 Obesity-related traits; TGCT cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs7666738 0.753 rs17027308 chr4:99091088 T/A cg18180107 chr4:99064573 C4orf37 0.55 4.94 0.41 2.45e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.649 rs738422 chr22:42123399 C/T cg17554472 chr22:41940697 POLR3H 0.45 4.84 0.4 3.72e-6 Vitiligo; TGCT cis rs9399135 0.967 rs7773126 chr6:135318390 A/G cg24558204 chr6:135376177 HBS1L 0.46 4.59 0.38 1.09e-5 Red blood cell count; TGCT cis rs7221595 0.673 rs115725560 chr17:3980493 T/A cg09580393 chr17:4869866 SPAG7 -0.39 -4.5 -0.37 1.56e-5 Functional impairment in major depressive disorder, bipolar disorder and schizophrenia; TGCT cis rs7635838 0.750 rs2648463 chr3:11403857 G/A cg00170343 chr3:11313890 ATG7 0.66 6.47 0.5 2.01e-9 HDL cholesterol; TGCT cis rs2486288 0.656 rs2413774 chr15:45549423 C/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs12681288 0.676 rs2701913 chr8:999982 A/T cg04851639 chr8:1020857 NA -0.29 -4.73 -0.39 6.03e-6 Schizophrenia; TGCT cis rs2760061 0.599 rs644794 chr1:228148670 T/C cg18477163 chr1:228402036 OBSCN -0.32 -6.31 -0.49 4.58e-9 Diastolic blood pressure; TGCT cis rs7017914 0.902 rs6472542 chr8:71654087 C/T cg23757474 chr8:71581111 LACTB2;XKR9 0.48 4.73 0.39 6.03e-6 Bone mineral density; TGCT cis rs1865760 0.566 rs2032445 chr6:26044812 T/A cg16482183 chr6:26056742 HIST1H1C 0.57 4.97 0.41 2.21e-6 Height; TGCT cis rs9486719 0.947 rs11757102 chr6:96885073 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT trans rs941408 1.000 rs4807332 chr19:2793289 T/C cg22153745 chr1:153894579 GATAD2B -0.64 -7.22 -0.54 4.49e-11 Total cholesterol levels; TGCT cis rs77633900 0.614 rs2454453 chr15:76913976 T/A cg21673338 chr15:77095150 SCAPER -0.51 -4.82 -0.4 4.09e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs7829975 0.774 rs57312668 chr8:8680477 G/A cg06636001 chr8:8085503 FLJ10661 0.68 5.98 0.47 2.17e-8 Mood instability; TGCT cis rs200810 0.964 rs28657486 chr6:97769261 T/C cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.52 -4.46 -0.37 1.81e-5 Body mass index; TGCT cis rs796364 0.662 rs11688415 chr2:201143409 C/T cg19045956 chr2:200819837 C2orf60;C2orf47 0.67 4.68 0.39 7.3e-6 Schizophrenia; TGCT cis rs6570726 0.791 rs387376 chr6:145822565 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs8008002 1.000 rs8008002 chr14:75865683 C/T cg20011974 chr14:75469661 EIF2B2 -0.5 -4.48 -0.37 1.65e-5 Response to paliperidone in schizophrenia (positive Marder score); TGCT cis rs3771570 1.000 rs41266959 chr2:242275579 G/A cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs35306767 0.903 rs11253494 chr10:937047 C/T cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs858239 0.539 rs10247268 chr7:23187179 G/A cg05602783 chr7:23145260 KLHL7 -0.68 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT trans rs6089829 0.925 rs4809270 chr20:61676709 C/A cg23505145 chr19:12996616 KLF1 0.96 10.09 0.67 7.8e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs11577318 0.853 rs11803933 chr1:26629465 G/C cg04990556 chr1:26633338 UBXN11 -0.63 -5.83 -0.46 4.58e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs2766692 1.000 rs4905941 chr14:100725438 A/G cg14866419 chr14:100704911 YY1 0.58 4.7 0.39 6.92e-6 Electroencephalographic traits in alcoholism; TGCT cis rs11031096 0.655 rs1822288 chr11:4212478 C/T cg18678763 chr11:4115507 RRM1 0.44 5.68 0.45 8.88e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7829975 0.582 rs448231 chr8:8790059 A/T cg15556689 chr8:8085844 FLJ10661 -0.64 -6.02 -0.48 1.85e-8 Mood instability; TGCT cis rs8033133 0.602 rs3803326 chr15:25328715 A/G cg14481604 chr15:25334117 SNORD116-22 -0.24 -5.35 -0.43 4.1e-7 Blood osmolality (transformed sodium); TGCT trans rs74910095 0.530 rs57645565 chr5:62931750 A/G cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs858239 0.539 rs10270695 chr7:23188988 C/T cg05602783 chr7:23145260 KLHL7 0.63 5.17 0.42 9.04e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs667920 0.575 rs9861150 chr3:136183320 G/T cg15507776 chr3:136538369 TMEM22 0.55 4.46 0.37 1.84e-5 Coronary artery disease; TGCT trans rs7618501 0.633 rs4688755 chr3:50064424 G/A cg21659725 chr3:3221576 CRBN -0.75 -9.02 -0.63 2.97e-15 Intelligence (multi-trait analysis); TGCT cis rs394563 0.717 rs548848 chr6:149782009 A/G cg03678062 chr6:149772716 ZC3H12D -0.39 -4.83 -0.4 4.03e-6 Dupuytren's disease; TGCT cis rs6490294 0.799 rs6489819 chr12:112328230 C/A cg10833066 chr12:111807467 FAM109A 0.39 5.81 0.46 4.86e-8 Mean platelet volume; TGCT cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg11644478 chr21:40555479 PSMG1 -0.63 -5.86 -0.47 3.89e-8 Cognitive function; TGCT cis rs926938 0.563 rs360576 chr1:115459174 A/C cg12756093 chr1:115239321 AMPD1 -0.42 -6.39 -0.5 3.05e-9 Autism; TGCT cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.72 7.34 0.55 2.47e-11 Prudent dietary pattern; TGCT cis rs7267979 0.932 rs1985737 chr20:25591468 T/A cg14121845 chr20:25566513 NINL 0.51 5.52 0.44 1.91e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7226408 0.817 rs72888915 chr18:34521261 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg22800045 chr5:56110881 MAP3K1 0.53 4.51 0.38 1.46e-5 Initial pursuit acceleration; TGCT cis rs4819052 0.851 rs35064782 chr21:46674360 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.62 0.56 5.74e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13242816 1.000 rs13242816 chr7:116189376 C/T cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs2120019 1.000 rs7173833 chr15:75369618 C/T cg09165964 chr15:75287851 SCAMP5 -1.16 -9.38 -0.64 3.97e-16 Blood trace element (Zn levels); TGCT cis rs2637266 1.000 rs12784382 chr10:78378348 G/T cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs709400 0.567 rs11624343 chr14:103859156 T/A cg26031613 chr14:104095156 KLC1 0.85 9.32 0.64 5.53e-16 Body mass index; TGCT cis rs4780401 0.609 rs16958588 chr16:11819330 G/A cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs611744 0.647 rs2594358 chr8:109256018 A/G cg21045802 chr8:109455806 TTC35 0.7 6.74 0.52 5.23e-10 Dupuytren's disease; TGCT cis rs597539 0.690 rs578791 chr11:68625809 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.83 7.28 0.55 3.28e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7582180 0.627 rs4407265 chr2:101005846 C/G cg08017756 chr2:100939284 LONRF2 -0.31 -5.01 -0.41 1.85e-6 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs6912958 0.605 rs2754247 chr6:88383571 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.9 -0.4 2.88e-6 Monocyte percentage of white cells; TGCT cis rs7412746 0.634 rs7521592 chr1:150821691 A/C cg04414720 chr1:150670196 GOLPH3L 0.39 4.83 0.4 3.97e-6 Melanoma; TGCT cis rs7589728 0.563 rs79892776 chr2:88470593 G/A cg04511125 chr2:88470314 THNSL2 0.83 6.93 0.53 2e-10 Plasma clusterin levels; TGCT cis rs2153535 0.542 rs1120393 chr6:8486890 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9479482 1.000 rs11155696 chr6:150357283 G/A cg03788504 chr6:150331562 NA -0.24 -4.63 -0.38 9.01e-6 Alopecia areata; TGCT cis rs10791097 0.629 rs11222361 chr11:130731424 T/G cg05962950 chr11:130786565 SNX19 0.84 10.71 0.69 2.4e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs10043228 1.000 rs12517508 chr5:115423574 C/T cg27022334 chr5:167645456 ODZ2 0.4 6.72 0.52 5.92e-10 Asthma or chronic obstructive pulmonary disease; TGCT cis rs155076 1.000 rs12870992 chr13:21846019 A/G cg14456004 chr13:21872349 NA 1.16 9.07 0.63 2.27e-15 White matter hyperintensity burden; TGCT cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg18252515 chr7:66147081 NA -0.79 -5.4 -0.44 3.34e-7 Diabetic kidney disease; TGCT cis rs74233809 1.000 rs3781285 chr10:104825665 C/G cg05855489 chr10:104503620 C10orf26 0.84 4.66 0.39 8.2e-6 Birth weight; TGCT cis rs7223966 0.515 rs2727315 chr17:61961458 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 4.8 0.4 4.55e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs513349 0.964 rs210139 chr6:33543409 A/C cg07679836 chr6:33548423 BAK1 0.3 4.45 0.37 1.88e-5 Platelet count; TGCT cis rs523522 0.962 rs7488320 chr12:120981630 G/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs1008375 1.000 rs1008375 chr4:17682834 T/C cg10189774 chr4:17578691 LAP3 0.54 5.11 0.42 1.18e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7582180 0.652 rs12997725 chr2:100935136 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.95e-6 Intelligence (multi-trait analysis); TGCT cis rs10927875 0.691 rs1048261 chr1:16340951 A/T cg14742211 chr1:16348397 CLCNKA 0.19 4.48 0.37 1.7e-5 Dilated cardiomyopathy; TGCT cis rs6754311 0.593 rs4954280 chr2:136420690 C/T cg07169764 chr2:136633963 MCM6 -0.65 -5.87 -0.47 3.74e-8 Mosquito bite size; TGCT cis rs1865760 1.000 rs3799371 chr6:25912816 A/G cg17042849 chr6:26104293 HIST1H4C 0.5 4.49 0.37 1.61e-5 Height; TGCT cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs6831352 1.000 rs1126671 chr4:100048414 T/C cg12011299 chr4:100065546 ADH4 0.41 5.2 0.42 8.11e-7 Alcohol dependence; TGCT cis rs700651 0.789 rs2196176 chr2:198904914 A/G cg00792783 chr2:198669748 PLCL1 0.59 5.09 0.42 1.28e-6 Intracranial aneurysm; TGCT cis rs73058052 0.569 rs10417980 chr19:50101713 T/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.58 0.45 1.42e-7 Fibrinogen levels; TGCT cis rs9926296 0.533 rs12102290 chr16:89812617 C/T cg21285383 chr16:89894308 SPIRE2 0.42 6.41 0.5 2.82e-9 Vitiligo; TGCT cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg11644478 chr21:40555479 PSMG1 1.04 10.81 0.7 1.38e-19 Cognitive function; TGCT cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg23758822 chr17:41437982 NA 0.78 7.29 0.55 3.14e-11 Menopause (age at onset); TGCT cis rs7715806 0.500 rs72633983 chr5:75002845 C/T cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs9326248 0.520 rs6589602 chr11:117037065 T/C cg01368799 chr11:117014884 PAFAH1B2 0.6 5.48 0.44 2.32e-7 Blood protein levels; TGCT cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg07092213 chr7:1199455 ZFAND2A -0.49 -5.52 -0.44 1.87e-7 Longevity;Endometriosis; TGCT cis rs617791 0.530 rs7934543 chr11:65752508 G/T cg09783858 chr11:65769428 EIF1AD;BANF1 0.5 4.56 0.38 1.2e-5 Breast cancer; TGCT cis rs9467711 0.675 rs58825580 chr6:26365679 T/G cg10795676 chr6:26370623 BTN3A2 -0.44 -4.89 -0.4 3.06e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12681288 0.676 rs2701910 chr8:1001246 G/T cg04851639 chr8:1020857 NA -0.32 -5.32 -0.43 4.74e-7 Schizophrenia; TGCT cis rs2982552 0.844 rs2982560 chr6:152055606 A/T cg22157087 chr6:152012887 ESR1 0.21 5.16 0.42 9.59e-7 Bone properties (heel); TGCT cis rs17881320 0.510 rs7221385 chr17:40562081 C/T cg05878104 chr17:40932452 WNK4 -0.98 -6.77 -0.52 4.62e-10 Atopic dermatitis; TGCT cis rs1552244 0.832 rs17050674 chr3:10027258 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.83 5.71 0.46 7.72e-8 Alzheimer's disease; TGCT cis rs35883536 0.525 rs2647321 chr1:101032006 T/G cg10298815 chr1:101004474 GPR88 0.26 4.7 0.39 6.89e-6 Monocyte count; TGCT cis rs2153535 0.580 rs4404802 chr6:8442052 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs6701037 0.625 rs67332874 chr1:175128537 G/A cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT cis rs111803315 1.000 rs112952088 chr14:60027907 C/T cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg24846343 chr22:24311635 DDTL 0.23 5.61 0.45 1.24e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs929354 0.713 rs6946947 chr7:156948787 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs9926296 0.605 rs886951 chr16:89836865 A/G cg27121462 chr16:89883253 FANCA 0.74 7.88 0.58 1.41e-12 Vitiligo; TGCT cis rs514406 0.560 rs1889033 chr1:53211887 A/G cg24675658 chr1:53192096 ZYG11B 0.83 10.11 0.67 6.99e-18 Monocyte count; TGCT cis rs9303401 0.659 rs17222621 chr17:56695923 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs6951245 1.000 rs78185558 chr7:1090183 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.32 -5.13 -0.42 1.11e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs12339966 0.581 rs62529409 chr9:11332000 T/G cg03488587 chr11:64876988 C11orf2 0.32 7.03 0.53 1.19e-10 Systolic blood pressure; TGCT cis rs10782582 0.609 rs56159153 chr1:76353498 T/G cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs2836974 0.897 rs34035316 chr21:40594023 T/C cg11890956 chr21:40555474 PSMG1 1.1 12.31 0.74 2.99e-23 Cognitive function; TGCT cis rs7599312 0.534 rs6735626 chr2:213403972 G/A cg16329650 chr2:213403929 ERBB4 1.06 16.47 0.83 5.13e-33 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9911578 1.000 rs302840 chr17:56673079 C/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.22 -0.49 7.03e-9 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg01084871 chr4:1340883 KIAA1530 0.59 4.62 0.38 9.57e-6 Longevity; TGCT cis rs17345786 1.000 rs73863360 chr3:101316837 G/A cg12386194 chr3:101231763 SENP7 0.61 5.75 0.46 6.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6840360 0.582 rs4696259 chr4:152310788 A/G cg17479576 chr4:152424074 FAM160A1 -0.65 -7.06 -0.54 1.02e-10 Intelligence (multi-trait analysis); TGCT trans rs7618501 0.521 rs3796386 chr3:49899795 G/A cg21659725 chr3:3221576 CRBN 0.73 8.19 0.59 2.76e-13 Intelligence (multi-trait analysis); TGCT cis rs9291683 0.546 rs13146686 chr4:10034933 A/G cg11266682 chr4:10021025 SLC2A9 0.56 6.24 0.49 6.19e-9 Bone mineral density; TGCT cis rs2243480 1.000 rs6970243 chr7:65388490 C/A cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs9926296 0.568 rs417323 chr16:89746277 T/G cg03388025 chr16:89894329 SPIRE2 -0.31 -4.47 -0.37 1.73e-5 Vitiligo; TGCT cis rs28595532 0.841 rs115209862 chr4:119742225 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7818688 0.697 rs57890591 chr8:95983130 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7572733 0.534 rs1607375 chr2:198800387 C/T cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg13395646 chr4:1353034 KIAA1530 0.38 4.71 0.39 6.42e-6 Obesity-related traits; TGCT cis rs2439831 0.867 rs2584702 chr15:43684914 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.87 6.04 0.48 1.64e-8 Lung cancer in ever smokers; TGCT cis rs9486719 1.000 rs72931061 chr6:96880285 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs1801251 1.000 rs2675971 chr2:233726154 A/G cg25237894 chr2:233734115 C2orf82 -0.33 -5.97 -0.47 2.34e-8 Coronary artery disease; TGCT cis rs6831352 0.918 rs17217949 chr4:100054312 A/G cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs11696501 0.688 rs2072974 chr20:44313401 G/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs7666738 0.687 rs6839454 chr4:99073914 T/C cg18180107 chr4:99064573 C4orf37 0.59 5.27 0.43 5.8e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs36051895 0.623 rs10974939 chr9:5056482 G/T cg02405213 chr9:5042618 JAK2 -0.75 -9.15 -0.63 1.42e-15 Pediatric autoimmune diseases; TGCT cis rs7666738 0.830 rs28622458 chr4:98916651 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.2 0.54 5.03e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9291683 0.509 rs6849717 chr4:9958719 T/C cg00071950 chr4:10020882 SLC2A9 -0.65 -8.23 -0.59 2.24e-13 Bone mineral density; TGCT cis rs1372520 0.564 rs356186 chr4:90705364 A/G cg01966878 chr4:90757139 SNCA -0.31 -4.79 -0.4 4.59e-6 Neuroticism; TGCT cis rs10751667 0.600 rs10751672 chr11:948712 T/C cg06064525 chr11:970664 AP2A2 -0.35 -7.92 -0.58 1.15e-12 Alzheimer's disease (late onset); TGCT cis rs9399135 0.967 rs4895434 chr6:135293365 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.79 0.39 4.76e-6 Red blood cell count; TGCT cis rs7043114 0.525 rs1053441 chr9:95147840 T/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.6 -0.45 1.32e-7 Height; TGCT cis rs2562456 0.876 rs11085465 chr19:21751790 A/G cg01304269 chr19:21688519 ZNF429 -0.58 -4.74 -0.39 5.78e-6 Pain; TGCT cis rs74417235 0.639 rs7443642 chr5:154053450 A/G cg08754654 chr5:154026448 NA -0.57 -5.13 -0.42 1.09e-6 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs2033711 0.905 rs893186 chr19:58969179 C/A cg13877915 chr19:58951672 ZNF132 0.85 9.63 0.65 9.76e-17 Uric acid clearance; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.04 0.82 4.85e-32 Prudent dietary pattern; TGCT cis rs6430585 0.583 rs7581814 chr2:136641593 C/G cg07169764 chr2:136633963 MCM6 -1.33 -12.69 -0.75 3.6e-24 Corneal structure; TGCT cis rs4975616 0.869 rs31490 chr5:1344458 G/A cg07493874 chr5:1342172 CLPTM1L -0.28 -6.6 -0.51 1.07e-9 Lung cancer; TGCT cis rs11650494 0.522 rs117821438 chr17:47325867 A/T cg08112188 chr17:47440006 ZNF652 1.06 5.45 0.44 2.65e-7 Prostate cancer; TGCT cis rs2996428 0.601 rs59414187 chr1:3762815 T/C cg13057898 chr1:3703894 LRRC47 0.22 4.68 0.39 7.24e-6 Red cell distribution width; TGCT cis rs546131 0.928 rs552868 chr11:34830694 G/A cg06937548 chr11:34938143 PDHX;APIP 0.66 5.84 0.46 4.34e-8 Lung disease severity in cystic fibrosis; TGCT cis rs1552244 0.882 rs6443276 chr3:10008905 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.4e-10 Alzheimer's disease; TGCT cis rs114540395 0.858 rs17760784 chr10:103156416 G/C cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg00080972 chr5:178986291 RUFY1 -0.58 -7.45 -0.56 1.37e-11 Lung cancer; TGCT cis rs1580019 0.844 rs4723159 chr7:32512804 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.86 8.3 0.6 1.46e-13 Cognitive ability; TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg07167872 chr1:205819463 PM20D1 -0.54 -6.82 -0.52 3.53e-10 Monocyte percentage of white cells; TGCT cis rs7267979 1.000 rs6037099 chr20:25356876 T/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4900538 0.963 rs2273905 chr14:102974999 T/C cg18135206 chr14:102964638 TECPR2 0.21 5.0 0.41 1.95e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7267979 0.932 rs417110 chr20:25458297 T/C cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7726839 0.574 rs72705014 chr5:619815 C/G cg25482853 chr8:67687455 SGK3 1.23 9.86 0.66 2.81e-17 Obesity-related traits; TGCT cis rs896854 0.738 rs481887 chr8:95967838 A/G cg16049864 chr8:95962084 TP53INP1 0.65 7.57 0.56 7.38e-12 Type 2 diabetes; TGCT cis rs7666738 0.830 rs921522 chr4:98841608 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.05 0.41 1.51e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs6089829 0.962 rs6062778 chr20:61663959 A/G cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs6906287 0.609 rs6938041 chr6:118852468 C/A cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs10782582 0.569 rs4549990 chr1:76125075 A/G cg22875332 chr1:76189707 ACADM -0.54 -6.36 -0.5 3.61e-9 Daytime sleep phenotypes; TGCT cis rs6089584 0.528 rs4925335 chr20:60627034 G/A cg13770153 chr20:60521292 NA -0.43 -5.15 -0.42 9.9e-7 Body mass index; TGCT cis rs7772486 0.686 rs9403746 chr6:146103768 C/A cg13319975 chr6:146136371 FBXO30 0.5 4.62 0.38 9.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 0.529 rs7195906 chr16:89806347 A/T cg04287289 chr16:89883240 FANCA 0.94 11.93 0.73 2.51e-22 Vitiligo; TGCT cis rs7833790 0.636 rs12544174 chr8:82731477 G/A cg23324259 chr8:82754387 SNX16 -0.61 -4.71 -0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs17345786 0.520 rs1476123 chr3:101313413 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.54 5.51 0.44 1.96e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10174077 0.874 rs4664490 chr2:152471923 C/G cg19508488 chr2:152266495 RIF1 -0.7 -6.69 -0.51 7e-10 Squamous cell lung carcinoma; TGCT cis rs2806561 0.734 rs667211 chr1:23516142 T/C cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs6952808 0.529 rs73038442 chr7:2139457 C/T cg04267008 chr7:1944627 MAD1L1 -0.36 -4.82 -0.4 4.05e-6 Bipolar disorder and schizophrenia; TGCT cis rs1008375 1.000 rs4698649 chr4:17692782 A/G cg18681998 chr4:17616180 MED28 0.76 7.28 0.55 3.42e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6951245 1.000 rs75488469 chr7:1102122 A/G cg23708337 chr7:1209742 NA 0.6 5.49 0.44 2.2e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9902453 0.845 rs10853135 chr17:28188675 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.62e-11 Coffee consumption (cups per day); TGCT cis rs7246657 0.941 rs10418729 chr19:37737065 A/C cg18154014 chr19:37997991 ZNF793 0.86 6.33 0.49 4.04e-9 Coronary artery calcification; TGCT cis rs7727544 0.716 rs7701414 chr5:131585958 A/G cg21474247 chr5:131268130 NA 0.32 4.71 0.39 6.41e-6 Blood metabolite levels; TGCT cis rs6964587 1.000 rs2237568 chr7:91622676 G/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs7937682 0.883 rs566647 chr11:111466607 A/G cg09085632 chr11:111637200 PPP2R1B 0.97 9.23 0.64 9.43e-16 Primary sclerosing cholangitis; TGCT cis rs6430585 0.702 rs73958637 chr2:136546927 C/T cg07169764 chr2:136633963 MCM6 1.21 11.47 0.72 3.36e-21 Corneal structure; TGCT cis rs7809950 0.678 rs7777950 chr7:107004672 T/C cg23024343 chr7:107201750 COG5 -0.43 -5.85 -0.47 4.12e-8 Coronary artery disease; TGCT cis rs2274273 0.713 rs56725788 chr14:55540101 A/G cg01923255 chr14:55878535 KIAA0831 0.57 4.89 0.4 3.03e-6 Protein biomarker; TGCT cis rs1541995 1.000 rs4984455 chr15:96357991 G/C cg00882281 chr15:96346592 NA 0.29 4.76 0.39 5.31e-6 Photic sneeze reflex; TGCT cis rs13108904 0.934 rs13128045 chr4:1305309 C/T cg00684032 chr4:1343700 KIAA1530 0.24 5.13 0.42 1.06e-6 Obesity-related traits; TGCT cis rs1008375 1.000 rs1558378 chr4:17650351 T/C cg18681998 chr4:17616180 MED28 1.06 12.43 0.74 1.57e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs896854 0.624 rs9297949 chr8:95969445 A/C cg23172400 chr8:95962367 TP53INP1 -0.39 -6.53 -0.51 1.5e-9 Type 2 diabetes; TGCT cis rs801193 1.000 rs2659912 chr7:66157999 G/C cg18876405 chr7:65276391 NA 0.36 5.31 0.43 4.87e-7 Aortic root size; TGCT cis rs5769707 0.846 rs5770610 chr22:50036897 A/C cg10356904 chr22:49881777 NA -0.22 -4.52 -0.38 1.4e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs651907 0.557 rs17347644 chr3:101547733 C/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.42 -0.5 2.6e-9 Colorectal cancer; TGCT cis rs6570726 0.791 rs1509214 chr6:145784606 A/C cg05347473 chr6:146136440 FBXO30 -0.49 -4.71 -0.39 6.66e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3845702 0.800 rs6744281 chr2:180844382 G/A cg01881094 chr2:180872142 CWC22 -1.08 -7.0 -0.53 1.39e-10 Schizophrenia; TGCT cis rs1903068 0.925 rs1551641 chr4:55993915 C/T cg09978860 chr4:56023921 NA 0.58 6.38 0.5 3.16e-9 Endometriosis; TGCT cis rs7829975 0.593 rs2921061 chr8:8317615 A/T cg08975724 chr8:8085496 FLJ10661 0.63 6.01 0.47 1.91e-8 Mood instability; TGCT cis rs9583531 0.600 rs9555726 chr13:111368316 C/T cg24331049 chr13:111365604 ING1 0.72 6.89 0.53 2.52e-10 Coronary artery disease; TGCT cis rs748404 0.578 rs507178 chr15:43610135 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.46e-6 Lung cancer; TGCT cis rs933688 0.759 rs1423593 chr5:90752351 T/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.06 9.27 0.64 7.2e-16 Smoking behavior; TGCT cis rs422249 0.720 rs174455 chr11:61656117 A/G cg19610905 chr11:61596333 FADS2 -0.67 -6.22 -0.49 6.89e-9 Trans fatty acid levels; TGCT cis rs9818758 0.607 rs34566463 chr3:49245077 T/C cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7666738 0.830 rs11097606 chr4:99011486 C/T cg05340658 chr4:99064831 C4orf37 0.46 5.13 0.42 1.09e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3858526 0.920 rs11511938 chr11:5928793 A/G cg13902645 chr11:5959945 NA -0.44 -4.8 -0.4 4.54e-6 DNA methylation (variation); TGCT cis rs919433 0.617 rs2037590 chr2:198584775 T/A cg00792783 chr2:198669748 PLCL1 -0.54 -4.96 -0.41 2.25e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs59197085 0.636 rs57573379 chr7:128465646 A/G cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg06481639 chr22:41940642 POLR3H -0.69 -6.02 -0.48 1.83e-8 Vitiligo; TGCT cis rs9486719 0.843 rs976357 chr6:96849679 C/T cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs67311347 1.000 rs73080137 chr3:40516412 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.61 0.38 9.99e-6 Renal cell carcinoma; TGCT cis rs7666738 0.830 rs13144771 chr4:99026935 G/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10488084 0.892 rs10226876 chr7:29970171 T/A cg19198568 chr7:28997866 TRIL 0.75 4.55 0.38 1.27e-5 Estradiol levels; TGCT cis rs6674176 0.932 rs7412307 chr1:44433864 C/G cg13606994 chr1:44402422 ARTN 0.47 4.7 0.39 6.93e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7618915 0.571 rs2251219 chr3:52584787 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.63 -6.16 -0.48 9.27e-9 Bipolar disorder; TGCT cis rs10089 0.953 rs4835940 chr5:127406596 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs9303401 0.659 rs17222523 chr17:56620501 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs2777491 0.957 rs7181911 chr15:41674060 T/C cg18705301 chr15:41695430 NDUFAF1 -0.76 -10.64 -0.69 3.42e-19 Ulcerative colitis; TGCT cis rs1865760 0.566 rs9379821 chr6:26054268 A/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.98 0.41 2.12e-6 Height; TGCT cis rs968451 0.789 rs1569501 chr22:39683534 A/T cg17798944 chr22:39715225 SNORD43;RPL3 0.79 7.84 0.58 1.76e-12 Primary biliary cholangitis; TGCT cis rs10510102 0.630 rs79960726 chr10:123713873 T/A cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT trans rs4750440 0.733 rs2446585 chr10:14028086 C/T cg23544566 chr7:157365643 PTPRN2 -0.38 -6.63 -0.51 9.44e-10 Adiponectin levels; TGCT cis rs1538970 0.962 rs3219489 chr1:45797505 C/G cg05343316 chr1:45956843 TESK2 0.65 5.2 0.42 8.04e-7 Platelet count; TGCT cis rs6951245 1.000 rs77305932 chr7:1100861 T/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12620999 0.941 rs2078469 chr2:237983273 C/G cg23555395 chr2:238036564 NA 0.28 4.93 0.4 2.57e-6 Systemic lupus erythematosus; TGCT cis rs1056053 0.514 rs3127331 chr6:166572744 C/T cg17219086 chr6:166541254 NA -0.19 -4.55 -0.38 1.24e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs597539 0.652 rs602364 chr11:68662167 C/T cg04772025 chr11:68637568 NA 0.6 6.77 0.52 4.63e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17401966 0.894 rs12722830 chr1:10395134 A/G cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs10779751 0.770 rs10864490 chr1:11236410 A/C cg08854313 chr1:11322531 MTOR 0.85 8.17 0.59 2.94e-13 Body mass index; TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs12780845 0.540 rs11254435 chr10:17224426 A/T cg01003015 chr10:17271136 VIM 0.52 4.61 0.38 9.97e-6 Homocysteine levels; TGCT cis rs4803468 1.000 rs11670757 chr19:41913431 G/T cg09537434 chr19:41945824 ATP5SL -0.93 -11.06 -0.7 3.31e-20 Height; TGCT cis rs7220711 1.000 rs59303349 chr17:41793668 A/G cg26893861 chr17:41843967 DUSP3 0.5 4.49 0.37 1.61e-5 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs9486719 1.000 rs12210146 chr6:96903962 A/G cg06623918 chr6:96969491 KIAA0776 0.98 8.77 0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs950776 0.642 rs922691 chr15:78963994 A/G cg03762349 chr15:79060523 ADAMTS7 0.27 5.4 0.44 3.23e-7 Sudden cardiac arrest; TGCT cis rs6933660 0.800 rs9383893 chr6:151757327 T/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.54 -4.93 -0.4 2.56e-6 Menarche (age at onset); TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg14159672 chr1:205819179 PM20D1 0.72 10.27 0.68 2.85e-18 Menarche (age at onset); TGCT cis rs6121246 0.559 rs10439608 chr20:30258814 T/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs7635838 0.718 rs2248971 chr3:11403441 T/C cg00170343 chr3:11313890 ATG7 0.66 6.47 0.5 2.01e-9 HDL cholesterol; TGCT trans rs7618501 1.000 rs6446295 chr3:49809063 G/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs9733 0.628 rs7540874 chr1:150702663 A/C cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs1887596 0.624 rs7992057 chr13:27153327 T/A cg01312412 chr13:27282625 NA 0.29 5.32 0.43 4.77e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs916888 0.738 rs199515 chr17:44856641 C/G cg15921436 chr17:44337874 NA -0.5 -6.76 -0.52 4.84e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6582630 0.599 rs12824838 chr12:38373584 G/T cg26384229 chr12:38710491 ALG10B -0.51 -4.55 -0.38 1.24e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs10782582 0.593 rs77208152 chr1:76124255 T/C cg10523679 chr1:76189770 ACADM -0.7 -7.51 -0.56 9.94e-12 Daytime sleep phenotypes; TGCT cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg08683831 chr4:1404607 NA 0.46 4.46 0.37 1.83e-5 Obesity-related traits; TGCT cis rs28595532 0.841 rs114768988 chr4:119744451 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs875971 1.000 rs2077593 chr7:65892530 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs8051431 0.840 rs8062422 chr16:72016839 G/T cg06353428 chr16:71660113 MARVELD3 0.58 4.62 0.38 9.32e-6 LDL cholesterol levels; TGCT cis rs28595532 1.000 rs56225646 chr4:119651217 T/C cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg03303774 chr4:1407052 NA 0.32 4.98 0.41 2.1e-6 Obesity-related traits; TGCT cis rs7772486 0.846 rs2492856 chr6:146323928 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.7 0.39 6.88e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs28595532 0.920 rs114168088 chr4:119772666 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs9911578 1.000 rs2531732 chr17:56548420 T/A cg12560992 chr17:57184187 TRIM37 -0.76 -9.28 -0.64 7.12e-16 Intelligence (multi-trait analysis); TGCT cis rs2295359 0.824 rs11209003 chr1:67601132 G/T cg03340356 chr1:67600835 NA 0.41 4.93 0.4 2.62e-6 Psoriasis; TGCT cis rs9467711 1.000 rs6903015 chr6:26322526 A/G cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2742417 0.603 rs1019129 chr3:45780780 T/C cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg03760483 chr17:6899297 ALOX12 0.47 5.38 0.44 3.55e-7 Tonsillectomy; TGCT cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.55 -5.58 -0.45 1.41e-7 Intelligence (multi-trait analysis); TGCT cis rs910316 1.000 rs4903284 chr14:75592483 G/C cg08847533 chr14:75593920 NEK9 0.95 10.55 0.69 5.83e-19 Height; TGCT cis rs28374715 0.733 rs7167706 chr15:41569644 C/A cg18705301 chr15:41695430 NDUFAF1 -0.86 -13.71 -0.78 1.28e-26 Ulcerative colitis; TGCT cis rs11098499 0.863 rs2306457 chr4:120472839 T/A cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs4242434 0.927 rs10095121 chr8:22538426 A/G cg03733263 chr8:22462867 KIAA1967 1.11 17.19 0.84 1.27e-34 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs11718455 0.960 rs11720974 chr3:43999111 G/C cg08738300 chr3:44038990 NA 0.83 6.19 0.49 8.13e-9 Coronary artery disease; TGCT cis rs79387448 0.745 rs7576324 chr2:103142994 G/A cg09003973 chr2:102972529 NA 0.91 6.0 0.47 2.06e-8 Gut microbiota (bacterial taxa); TGCT cis rs12620999 1.000 rs28727919 chr2:238003313 C/T cg23555395 chr2:238036564 NA 0.29 4.89 0.4 3e-6 Systemic lupus erythematosus; TGCT trans rs3107575 0.572 rs73169365 chr3:165319778 T/C cg04140596 chr1:228404239 OBSCN 0.72 6.63 0.51 9.27e-10 Morning vs. evening chronotype; TGCT cis rs2288884 0.806 rs60193983 chr19:52585912 T/G cg13540795 chr19:52551618 ZNF432 -0.61 -5.28 -0.43 5.48e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs4074961 0.692 rs11264075 chr1:38083941 C/G cg17933807 chr1:38061675 GNL2 0.95 11.07 0.71 3.13e-20 Axial length; TGCT cis rs875971 0.597 rs11771318 chr7:66062480 G/T cg18876405 chr7:65276391 NA -0.39 -6.2 -0.49 7.65e-9 Aortic root size; TGCT cis rs9611519 0.964 rs20551 chr22:41548008 A/G cg03806693 chr22:41940476 POLR3H -0.67 -6.21 -0.49 7.35e-9 Neuroticism; TGCT cis rs1008375 0.544 rs56227066 chr4:17565713 G/A cg18681998 chr4:17616180 MED28 0.73 7.08 0.54 9.45e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg01017244 chr2:74357527 NA 0.47 7.41 0.55 1.7e-11 Gestational age at birth (maternal effect); TGCT cis rs4901869 0.966 rs12878614 chr14:59339477 A/C cg02291164 chr14:59296302 NA 0.23 4.49 0.37 1.61e-5 Panic disorder; TGCT cis rs9611565 0.568 rs2413656 chr22:42129357 G/T cg06634786 chr22:41940651 POLR3H 0.8 7.42 0.55 1.63e-11 Vitiligo; TGCT cis rs3617 0.573 rs2336667 chr3:52916363 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.92 0.4 2.69e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9926296 0.605 rs1800287 chr16:89858525 C/G cg04287289 chr16:89883240 FANCA 0.93 12.17 0.74 6.69e-23 Vitiligo; TGCT cis rs1157477 0.651 rs55950110 chr18:73887018 C/T cg07537417 chr18:74332553 NA -0.65 -4.67 -0.39 7.59e-6 Systolic blood pressure (cigarette smoking interaction); TGCT cis rs67478160 0.643 rs4900594 chr14:104251006 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.42 -0.5 2.64e-9 Schizophrenia; TGCT cis rs3784262 0.900 rs12911071 chr15:58314848 G/A cg12031962 chr15:58353849 ALDH1A2 -0.52 -7.93 -0.58 1.1e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs1570884 0.536 rs1359541 chr13:50158939 A/G cg03651054 chr13:50194643 NA 0.34 5.57 0.45 1.53e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs1577917 0.545 rs9450325 chr6:86475814 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.58 4.84 0.4 3.8e-6 Response to antipsychotic treatment; TGCT cis rs1218582 0.710 rs9793588 chr1:154878878 C/G cg06221963 chr1:154839813 KCNN3 -0.73 -11.82 -0.73 4.65e-22 Prostate cancer; TGCT cis rs3087591 1.000 rs4795577 chr17:29456879 T/G cg24425628 chr17:29625626 OMG;NF1 0.46 7.25 0.55 3.92e-11 Hip circumference; TGCT cis rs7822232 1.000 rs6558296 chr8:145143802 G/A cg14631276 chr8:145163102 KIAA1875 -0.56 -5.05 -0.41 1.55e-6 Blood metabolite levels; TGCT cis rs10972341 1.000 rs10972350 chr9:35149831 A/G cg00812861 chr9:35114699 KIAA1539 0.32 4.97 0.41 2.18e-6 Weight; TGCT cis rs9467773 1.000 rs6924838 chr6:26571756 C/T cg05738196 chr6:26577821 NA 0.9 12.48 0.75 1.16e-23 Intelligence (multi-trait analysis); TGCT cis rs3741404 0.512 rs4980504 chr11:63873083 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.67 -6.28 -0.49 5.22e-9 Platelet count; TGCT cis rs1552244 0.872 rs6771931 chr3:10113408 C/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs1005277 0.579 rs2474575 chr10:38387901 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6570726 0.791 rs9403734 chr6:145931459 C/G cg05347473 chr6:146136440 FBXO30 0.53 4.94 0.41 2.5e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.933 rs35355150 chr6:26526039 G/A cg05738196 chr6:26577821 NA 0.83 10.98 0.7 5.27e-20 Intelligence (multi-trait analysis); TGCT cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 0.53 6.16 0.48 9.43e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs9527 0.590 rs7089680 chr10:104802071 C/T cg04362960 chr10:104952993 NT5C2 -0.65 -5.59 -0.45 1.36e-7 Arsenic metabolism; TGCT trans rs12191082 0.646 rs17470473 chr6:46883779 C/T cg15621338 chr7:128577916 IRF5 -1.22 -6.68 -0.51 7.28e-10 Mean platelet volume; TGCT cis rs7917772 0.503 rs10748825 chr10:104293609 A/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1878931 0.543 rs1129568 chr16:3483475 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.9 9.51 0.65 1.93e-16 Body mass index (adult); TGCT cis rs453301 0.506 rs476845 chr8:8622877 A/G cg06636001 chr8:8085503 FLJ10661 -0.51 -4.49 -0.37 1.62e-5 Joint mobility (Beighton score); TGCT cis rs13191362 1.000 rs13204013 chr6:163002480 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs11696501 0.739 rs6073820 chr20:44249272 T/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.79 -0.4 4.67e-6 Brain structure; TGCT cis rs6860806 0.507 rs169256 chr5:131688533 A/G cg16647868 chr5:131706066 SLC22A5 0.3 4.49 0.37 1.62e-5 Breast cancer; TGCT cis rs2486012 0.826 rs3011229 chr1:44328017 A/G cg12908607 chr1:44402522 ARTN -0.69 -5.57 -0.45 1.49e-7 Intelligence (multi-trait analysis); TGCT cis rs896854 0.818 rs13262110 chr8:95926890 C/T cg16049864 chr8:95962084 TP53INP1 -0.71 -9.71 -0.66 6.44e-17 Type 2 diabetes; TGCT cis rs16958440 0.867 rs16949157 chr18:44691324 A/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs6912958 0.558 rs7741825 chr6:88327338 G/C cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -4.96 -0.41 2.23e-6 Monocyte percentage of white cells; TGCT cis rs78456975 1.000 rs13392535 chr2:1542634 G/T cg01028140 chr2:1542097 TPO -0.36 -4.63 -0.38 9.02e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9291683 0.595 rs35250962 chr4:10048271 C/T cg00071950 chr4:10020882 SLC2A9 0.68 8.48 0.61 5.73e-14 Bone mineral density; TGCT cis rs9447004 0.584 rs56093139 chr6:74432923 C/T cg23004174 chr6:74404879 CD109 0.22 4.58 0.38 1.14e-5 Blood protein levels;Calcium levels; TGCT cis rs7523050 0.643 rs35665867 chr1:109395436 G/A cg08274380 chr1:109419600 GPSM2 1.29 6.23 0.49 6.72e-9 Fat distribution (HIV); TGCT cis rs4689592 0.503 rs3857180 chr4:7073899 T/G cg02503808 chr4:7069936 GRPEL1 -0.97 -7.94 -0.58 1.01e-12 Monocyte percentage of white cells; TGCT cis rs2180341 0.960 rs9398840 chr6:127669744 G/A cg24812749 chr6:127587940 RNF146 1.01 7.62 0.56 5.59e-12 Breast cancer; TGCT cis rs7819412 0.538 rs4523214 chr8:10970773 T/A cg21775007 chr8:11205619 TDH -0.52 -5.03 -0.41 1.67e-6 Triglycerides; TGCT cis rs6429082 0.818 rs167092 chr1:235642359 A/G cg26050004 chr1:235667680 B3GALNT2 0.62 5.58 0.45 1.43e-7 Adiposity; TGCT cis rs10504229 1.000 rs1390411 chr8:58194146 C/A cg08219700 chr8:58056026 NA 0.3 4.55 0.38 1.24e-5 Developmental language disorder (linguistic errors); TGCT cis rs9929218 0.731 rs72785179 chr16:68767912 C/T cg01251360 chr16:68772225 CDH1 0.29 4.95 0.41 2.34e-6 Colorectal cancer; TGCT cis rs9926296 0.656 rs2376882 chr16:89827002 T/C cg27121462 chr16:89883253 FANCA 0.53 4.99 0.41 2.01e-6 Vitiligo; TGCT cis rs12477438 0.798 rs4850891 chr2:99574642 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.21 -0.49 7.35e-9 Chronic sinus infection; TGCT cis rs7715806 0.500 rs17649266 chr5:75001252 C/T cg19683494 chr5:74908142 NA -0.54 -4.49 -0.37 1.58e-5 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7582180 0.627 rs4851312 chr2:101011241 G/A cg08017756 chr2:100939284 LONRF2 -0.31 -5.01 -0.41 1.86e-6 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.532 rs284892 chr15:76721037 A/G cg22467129 chr15:76604101 ETFA -0.44 -4.86 -0.4 3.41e-6 Blood metabolite levels; TGCT cis rs9682041 0.877 rs10804841 chr3:170072031 T/A cg11886554 chr3:170076028 SKIL 0.55 4.58 0.38 1.11e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs2842992 0.789 rs2146163 chr6:160224346 T/C cg11366901 chr6:160182831 ACAT2 1.03 6.98 0.53 1.59e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs17152411 1.000 rs17152377 chr10:126592852 T/G cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT trans rs561341 1.000 rs542132 chr17:30307193 A/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs11167764 0.895 rs6882824 chr5:141474300 A/G cg23435118 chr5:141488016 NDFIP1 -0.27 -4.53 -0.38 1.35e-5 Crohn's disease; TGCT cis rs9560113 1.000 rs9560103 chr13:112174253 G/A cg14154082 chr13:112174009 NA 0.34 4.58 0.38 1.09e-5 Menarche (age at onset); TGCT cis rs2380220 0.872 rs4546494 chr6:95990626 A/C cg04719120 chr6:96025338 MANEA 0.68 4.79 0.4 4.59e-6 Behavioural disinhibition (generation interaction); TGCT cis rs1992660 0.504 rs7712308 chr5:40351716 A/G cg01087697 chr5:40835557 RPL37 0.52 4.7 0.39 6.92e-6 Crohn's disease; TGCT cis rs2204008 0.807 rs11182461 chr12:38539288 T/C cg13010199 chr12:38710504 ALG10B 0.65 5.18 0.42 8.78e-7 Bladder cancer; TGCT cis rs3806843 0.576 rs246047 chr5:140328337 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs6088590 0.687 rs73106933 chr20:33287425 T/C cg06115741 chr20:33292138 TP53INP2 0.58 4.88 0.4 3.14e-6 Coronary artery disease; TGCT cis rs597539 0.652 rs553875 chr11:68695144 T/G cg21862992 chr11:68658383 NA 0.46 6.32 0.49 4.31e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6450176 1.000 rs12654393 chr5:53302620 A/C ch.5.1024479R chr5:53302184 ARL15 0.53 5.1 0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs875971 0.862 rs1983372 chr7:65611351 C/T cg11764359 chr7:65958608 NA -0.56 -5.09 -0.42 1.31e-6 Aortic root size; TGCT cis rs7432375 0.901 rs4038587 chr3:136381368 A/C cg12473912 chr3:136751656 NA -0.36 -5.06 -0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs79349575 0.749 rs957557 chr17:47003221 G/T cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs10875746 0.669 rs4760701 chr12:48698518 A/G cg20731937 chr12:48336164 NA 0.58 4.76 0.39 5.24e-6 Longevity (90 years and older); TGCT cis rs6933660 0.745 rs9371517 chr6:151739810 G/T cg17179660 chr6:151773299 C6orf211;RMND1 -0.51 -4.61 -0.38 9.89e-6 Menarche (age at onset); TGCT cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg04025307 chr7:1156635 C7orf50 0.2 4.73 0.39 5.94e-6 Longevity;Endometriosis; TGCT cis rs9976767 0.637 rs9984108 chr21:43825628 T/G cg23042151 chr21:43824109 UBASH3A -0.23 -5.14 -0.42 1.02e-6 Type 1 diabetes; TGCT trans rs3749237 0.964 rs2352967 chr3:49871641 C/T cg21659725 chr3:3221576 CRBN 0.63 6.65 0.51 8.42e-10 Resting heart rate; TGCT cis rs849210 0.517 rs13011981 chr2:206202372 A/G cg11793701 chr2:206547163 NRP2 -0.57 -4.54 -0.38 1.31e-5 Tonsillectomy; TGCT cis rs1670533 1.000 rs4690215 chr4:1054619 G/C cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT trans rs561341 0.941 rs501773 chr17:30314435 T/G cg20587970 chr11:113659929 NA -1.05 -12.74 -0.75 2.84e-24 Hip circumference adjusted for BMI; TGCT cis rs6088590 1.000 rs6087626 chr20:33347328 C/T cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT cis rs9796 0.689 rs8032195 chr15:41448790 G/A cg18705301 chr15:41695430 NDUFAF1 -0.54 -7.03 -0.53 1.2e-10 Menopause (age at onset); TGCT cis rs933688 1.000 rs2367526 chr5:90740525 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.94 8.08 0.59 4.83e-13 Smoking behavior; TGCT cis rs9611519 1.000 rs9611520 chr22:41613303 C/T cg03806693 chr22:41940476 POLR3H -0.68 -6.38 -0.5 3.17e-9 Neuroticism; TGCT cis rs854765 0.583 rs10048206 chr17:17866897 A/G cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs72647484 0.642 rs28617726 chr1:22586280 G/A cg21876283 chr1:22149684 LDLRAD2;HSPG2 0.27 4.55 0.38 1.26e-5 Colorectal cancer; TGCT cis rs1371867 0.875 rs1788176 chr8:101332112 A/G cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT trans rs561341 1.000 rs527256 chr17:30321293 C/G cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs9311474 0.507 rs6787154 chr3:52784416 C/T cg10802521 chr3:52805072 NEK4 -0.8 -10.49 -0.69 8.31e-19 Electroencephalogram traits; TGCT cis rs17401966 0.931 rs12131441 chr1:10428952 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg06634786 chr22:41940651 POLR3H 0.99 7.75 0.57 2.81e-12 Vitiligo; TGCT cis rs9467773 0.935 rs1056668 chr6:26510605 C/T cg26531700 chr6:26746687 NA 0.61 6.25 0.49 6.06e-9 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs642743 0.517 rs157077 chr10:106037894 C/T cg00899160 chr10:106034472 GSTO2 -0.4 -5.09 -0.42 1.29e-6 Left ventricular obstructive tract defect (maternal effect); TGCT cis rs2730245 0.527 rs62476464 chr7:158698063 C/T cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs858239 0.601 rs764533 chr7:23153875 C/T cg05602783 chr7:23145260 KLHL7 -0.62 -5.22 -0.42 7.15e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs56114371 0.777 rs200482 chr6:27773904 G/A cg08798685 chr6:27730294 NA -0.33 -4.53 -0.38 1.34e-5 Breast cancer; TGCT cis rs6690583 0.623 rs12030730 chr1:85454109 C/G cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs992157 0.835 rs2292555 chr2:219146882 G/C cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg03188948 chr7:1209495 NA 0.5 7.14 0.54 6.77e-11 Longevity;Endometriosis; TGCT cis rs1568889 1.000 rs61889046 chr11:28297024 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.82 8.61 0.61 2.73e-14 Bipolar disorder; TGCT cis rs9372253 0.934 rs9320327 chr6:110715194 T/A cg19196401 chr6:110721138 DDO -0.5 -7.32 -0.55 2.8e-11 Platelet distribution width; TGCT cis rs80033912 0.640 rs6785832 chr3:49224316 C/T cg18654377 chr3:49208889 KLHDC8B -0.35 -4.71 -0.39 6.53e-6 Intelligence (multi-trait analysis); TGCT cis rs2299587 0.554 rs17634704 chr8:17753306 A/G cg01800426 chr8:17659068 MTUS1 -0.58 -5.12 -0.42 1.12e-6 Economic and political preferences; TGCT cis rs367943 0.871 rs348940 chr5:112824530 C/A cg12552261 chr5:112820674 MCC -0.22 -4.7 -0.39 6.84e-6 Type 2 diabetes; TGCT cis rs10751667 0.666 rs7395823 chr11:942701 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg11905131 chr22:24372483 LOC391322 -0.95 -11.19 -0.71 1.58e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1347297 0.526 rs919177 chr2:179258923 C/T cg03991736 chr2:179345203 MIR548N;PLEKHA3 -0.51 -5.01 -0.41 1.86e-6 Alzheimer disease and age of onset; TGCT cis rs9914988 0.887 rs12451790 chr17:27112000 C/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1799949 0.965 rs799910 chr17:41279561 G/C cg10047753 chr17:41438598 NA 0.74 7.06 0.54 1.04e-10 Menopause (age at onset); TGCT cis rs10114408 0.959 rs1316472 chr9:96649157 C/G cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2013441 1.000 rs2013576 chr17:20167692 G/C cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs7296418 0.961 rs1790121 chr12:123604492 G/A cg00376283 chr12:123451042 ABCB9 0.83 7.54 0.56 8.67e-12 Platelet count; TGCT cis rs1451375 1.000 rs921450 chr7:50623260 A/G cg18232548 chr7:50535776 DDC -0.41 -6.46 -0.5 2.13e-9 Malaria; TGCT cis rs524281 0.861 rs7120326 chr11:65849256 C/T cg00563793 chr11:65837595 PACS1 0.56 4.74 0.39 5.69e-6 Electroencephalogram traits; TGCT cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 9.05e-28 Menopause (age at onset); TGCT cis rs911555 0.755 rs2765049 chr14:103975039 G/A cg12935359 chr14:103987150 CKB 0.33 4.57 0.38 1.15e-5 Intelligence (multi-trait analysis); TGCT cis rs765787 0.530 rs1648287 chr15:45516956 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.37 -0.43 3.78e-7 Uric acid levels; TGCT cis rs769267 0.930 rs7254927 chr19:19404786 C/G cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.82 7.52 0.56 9.42e-12 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.567 rs2811 chr20:30194248 A/G cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs6450176 0.909 rs67721004 chr5:53290571 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.09e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs1865760 1.000 rs3752421 chr6:25918688 G/A cg16482183 chr6:26056742 HIST1H1C 0.51 4.55 0.38 1.25e-5 Height; TGCT cis rs4819052 0.590 rs414743 chr21:46512075 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.44 0.37 1.99e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs79387448 0.745 rs72993720 chr2:103121269 A/T cg09003973 chr2:102972529 NA 0.85 5.65 0.45 1.03e-7 Gut microbiota (bacterial taxa); TGCT cis rs1033284 0.748 rs1249433 chr2:141945852 C/T cg20443778 chr2:142887886 LRP1B 0.47 4.48 0.37 1.66e-5 Blood pressure (smoking interaction); TGCT cis rs2033562 0.505 rs9297327 chr8:103540181 A/C cg09916692 chr8:103549622 NA -0.22 -4.47 -0.37 1.71e-5 IgA nephropathy; TGCT cis rs7027203 0.557 rs2490997 chr9:96522109 C/T cg14598338 chr9:96623480 NA -0.49 -7.04 -0.53 1.18e-10 DNA methylation (variation); TGCT cis rs35306767 0.903 rs11253495 chr10:937064 C/T cg26597838 chr10:835615 NA 0.73 10.11 0.67 6.86e-18 Eosinophil percentage of granulocytes; TGCT cis rs7666738 0.830 rs35433756 chr4:99070555 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9318086 0.935 rs9652081 chr13:24435510 C/T cg25267304 chr13:24462978 PCOTH;MIPEP -0.68 -6.87 -0.52 2.82e-10 Myopia (pathological); TGCT cis rs524023 0.837 rs12362590 chr11:64352540 T/A cg07733098 chr11:64478343 NRXN2 0.31 4.56 0.38 1.2e-5 Urate levels in obese individuals; TGCT cis rs769267 0.931 rs2965193 chr19:19454828 G/A cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs6754311 0.593 rs656326 chr2:136428460 A/C cg07169764 chr2:136633963 MCM6 0.66 5.89 0.47 3.45e-8 Mosquito bite size; TGCT cis rs10851411 0.908 rs3986280 chr15:42850380 A/G cg23803468 chr15:43513504 EPB42 0.27 5.19 0.42 8.38e-7 Glucose homeostasis traits; TGCT cis rs12497850 0.897 rs7373778 chr3:48836392 C/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT trans rs9951602 0.512 rs4799246 chr18:76653417 A/G cg02800362 chr5:177631904 HNRNPAB 1.14 12.9 0.76 1.17e-24 Obesity-related traits; TGCT cis rs2387326 1.000 rs10764751 chr10:129926420 A/C cg03458096 chr10:129105057 DOCK1 -0.3 -4.67 -0.39 7.78e-6 Select biomarker traits; TGCT cis rs11585357 0.895 rs72633806 chr1:17617943 A/G cg08277548 chr1:17600880 PADI3 -0.96 -9.78 -0.66 4.35e-17 Hair shape; TGCT cis rs7772486 0.754 rs6937661 chr6:146113299 T/C cg05347473 chr6:146136440 FBXO30 -0.53 -4.99 -0.41 2.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4072705 0.617 rs10283445 chr9:127243637 A/G cg13476313 chr9:127244764 NR5A1 0.29 4.71 0.39 6.66e-6 Menarche (age at onset); TGCT cis rs6754311 0.681 rs4954493 chr2:136609975 T/C cg07169764 chr2:136633963 MCM6 -0.66 -6.13 -0.48 1.08e-8 Mosquito bite size; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs2842992 0.768 rs2273824 chr6:160211445 C/T cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs1799949 0.859 rs11657004 chr17:41442751 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.45 4.84 0.4 3.81e-6 Menopause (age at onset); TGCT cis rs2072499 0.833 rs2842873 chr1:156204653 C/T cg06970220 chr1:156163860 SLC25A44 0.66 6.0 0.47 2.01e-8 Testicular germ cell tumor; TGCT cis rs1215050 0.740 rs783938 chr4:99010336 A/T cg17366294 chr4:99064904 C4orf37 -0.53 -5.41 -0.44 3.06e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4499344 0.556 rs259231 chr19:33129067 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.3 0.6 1.52e-13 Mean platelet volume; TGCT cis rs137699 0.959 rs5757631 chr22:39755953 T/C cg11247378 chr22:39784982 NA -0.47 -5.2 -0.42 8.13e-7 IgG glycosylation; TGCT cis rs9457247 1.000 rs2757047 chr6:167374489 C/T cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.05e-6 Crohn's disease; TGCT cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg13683864 chr3:40499215 RPL14 -1.16 -13.09 -0.76 3.9e-25 Renal cell carcinoma; TGCT cis rs597539 0.652 rs667989 chr11:68685776 T/A cg04772025 chr11:68637568 NA 0.6 6.74 0.52 5.3e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs644799 0.526 rs530914 chr11:95632156 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.49 4.99 0.41 1.99e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs425277 1.000 rs427811 chr1:2075560 T/G cg24578937 chr1:2090814 PRKCZ 0.3 7.05 0.53 1.1e-10 Height; TGCT cis rs35883536 0.647 rs10875317 chr1:101045438 G/T cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT trans rs2469997 1.000 rs2470028 chr8:120365878 A/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs7552404 0.924 rs67757078 chr1:76169456 G/A cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12220898 0.619 rs10735221 chr10:50483563 G/A cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT trans rs35934224 0.783 rs16984299 chr22:19863593 C/T cg07537964 chr19:3722604 NA -0.7 -6.7 -0.52 6.57e-10 Glaucoma (primary open-angle); TGCT cis rs12039431 0.788 rs7535432 chr1:38051585 C/T cg17933807 chr1:38061675 GNL2 -0.8 -7.91 -0.58 1.24e-12 Epithelial ovarian cancer; TGCT cis rs1048238 0.506 rs848195 chr1:16286522 A/G cg21385522 chr1:16154831 NA -0.61 -6.93 -0.53 2.01e-10 Systolic blood pressure; TGCT cis rs9902453 0.934 rs4343336 chr17:28488236 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs6089829 0.925 rs2277767 chr20:61666937 G/A cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs12579753 1.000 rs10862368 chr12:82244514 C/T cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs10791097 0.694 rs4436551 chr11:130755739 A/G cg14779329 chr11:130786720 SNX19 -0.29 -5.0 -0.41 1.95e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs13256369 0.802 rs12153 chr8:8560909 G/C cg18904891 chr8:8559673 CLDN23 0.57 5.27 0.43 5.87e-7 Obesity-related traits; TGCT cis rs6951245 0.706 rs1133116 chr7:1195215 A/C cg09177884 chr7:1199841 ZFAND2A -0.72 -4.47 -0.37 1.72e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7772486 0.875 rs2748502 chr6:146298239 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.92 0.4 2.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs68170813 0.559 rs74584447 chr7:106944755 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs644799 0.540 rs10831422 chr11:95478968 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.64 6.14 0.48 1.01e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9399401 0.710 rs12190271 chr6:142681409 A/G cg03128060 chr6:142623767 GPR126 -0.37 -4.46 -0.37 1.82e-5 Chronic obstructive pulmonary disease; TGCT cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg01802117 chr1:53393560 SCP2 0.44 5.34 0.43 4.33e-7 Monocyte count; TGCT cis rs2762353 0.935 rs1892249 chr6:25768992 A/G cg12310025 chr6:25882481 NA 0.53 5.5 0.44 2.03e-7 Blood metabolite levels; TGCT cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg10802521 chr3:52805072 NEK4 -0.61 -6.53 -0.51 1.55e-9 Bipolar disorder; TGCT cis rs9611565 0.921 rs6002333 chr22:41719469 C/T cg06634786 chr22:41940651 POLR3H -0.72 -6.8 -0.52 3.9e-10 Vitiligo; TGCT trans rs1814175 0.817 rs1818890 chr11:49856882 T/C cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs595982 0.527 rs56021835 chr19:49369989 G/A cg21252483 chr19:49399788 TULP2 -0.42 -6.39 -0.5 3.02e-9 Red cell distribution width; TGCT cis rs17253792 0.822 rs78323463 chr14:56045451 T/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs11098499 0.955 rs35197422 chr4:120169314 T/G cg24670566 chr4:120433619 PDE5A 0.23 4.58 0.38 1.13e-5 Corneal astigmatism; TGCT cis rs11578119 0.872 rs114909548 chr1:170542820 G/A cg09767346 chr1:170501363 GORAB 0.59 4.66 0.39 8.03e-6 Male-pattern baldness; TGCT cis rs2836633 0.929 rs8130434 chr21:40036243 C/T cg12884169 chr21:40033163 ERG -0.43 -4.69 -0.39 7.2e-6 Coronary artery disease; TGCT cis rs6665290 0.904 rs1343744 chr1:227183022 C/T cg10327440 chr1:227177885 CDC42BPA -0.98 -20.16 -0.88 6.05e-41 Myeloid white cell count; TGCT cis rs2288884 1.000 rs76368799 chr19:52561507 A/G cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs950169 0.922 rs62029585 chr15:84951874 C/G cg17173187 chr15:85201210 NMB 0.59 5.87 0.47 3.71e-8 Schizophrenia; TGCT cis rs10782582 0.609 rs1770889 chr1:76401166 A/G cg03433033 chr1:76189801 ACADM -0.52 -5.13 -0.42 1.07e-6 Daytime sleep phenotypes; TGCT cis rs12580194 1.000 rs12582734 chr12:55689572 C/A cg20672549 chr12:56432144 IKZF4 0.27 4.75 0.39 5.55e-6 Cancer; TGCT cis rs2153535 0.580 rs9406158 chr6:8464152 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7246657 0.943 rs7255972 chr19:37933841 T/C cg18154014 chr19:37997991 ZNF793 0.95 6.52 0.51 1.58e-9 Coronary artery calcification; TGCT cis rs2637266 0.905 rs11001834 chr10:78360494 T/C cg18941641 chr10:78392320 NA 0.43 5.57 0.45 1.49e-7 Pulmonary function; TGCT cis rs9372498 0.572 rs62422190 chr6:118909235 A/G cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs116095464 0.558 rs73024831 chr5:257192 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs7586879 0.551 rs7565460 chr2:25130073 C/T cg01884057 chr2:25150051 NA 0.35 6.87 0.53 2.72e-10 Body mass index; TGCT cis rs9383153 0.793 rs9358090 chr6:16348728 G/A cg14009473 chr6:15502099 JARID2 0.62 4.93 0.4 2.58e-6 Gambling; TGCT cis rs4332037 0.539 rs868754 chr7:2033780 G/C cg25834613 chr7:1915315 MAD1L1 -0.53 -4.99 -0.41 2.02e-6 Bipolar disorder; TGCT cis rs71435601 0.628 rs312983 chr2:21378580 A/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs2180341 0.924 rs877661 chr6:127587915 T/G cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs459571 0.635 rs379471 chr9:136890649 G/A cg13789015 chr9:136890014 NCRNA00094 0.39 7.2 0.54 5.17e-11 Platelet distribution width; TGCT cis rs155076 1.000 rs155076 chr13:21870114 A/G cg11317459 chr13:21872234 NA -1.3 -11.71 -0.72 8.86e-22 White matter hyperintensity burden; TGCT cis rs9921338 0.887 rs7189044 chr16:11442196 G/C cg00044050 chr16:11439710 C16orf75 -0.91 -7.1 -0.54 8.47e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs2153535 0.580 rs6918391 chr6:8461178 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs114540395 0.925 rs78646802 chr10:103392029 A/G cg18276125 chr10:102749041 C10orf2 0.41 5.04 0.41 1.58e-6 Schizophrenia; TGCT cis rs7772486 0.806 rs2253648 chr6:146199296 G/A cg23711669 chr6:146136114 FBXO30 0.88 9.63 0.65 9.94e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs67311347 1.000 rs2305521 chr3:40429183 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.29e-6 Renal cell carcinoma; TGCT cis rs2120019 1.000 rs35577967 chr15:75354621 G/A cg17294928 chr15:75287854 SCAMP5 -0.84 -6.3 -0.49 4.75e-9 Blood trace element (Zn levels); TGCT cis rs9303542 0.625 rs7225995 chr17:46596268 G/C cg25032089 chr17:46643351 HOXB3 0.56 5.5 0.44 2.11e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg20607798 chr8:58055168 NA 0.62 5.23 0.43 6.99e-7 Developmental language disorder (linguistic errors); TGCT cis rs790123 0.933 rs812596 chr3:122382301 A/T cg22896480 chr3:122379438 NA 0.2 5.08 0.42 1.35e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs6840360 0.667 rs4266275 chr4:152348064 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs950776 0.642 rs12905641 chr15:78964362 A/G cg21242079 chr15:79101063 ADAMTS7 0.33 5.05 0.41 1.55e-6 Sudden cardiac arrest; TGCT cis rs1577917 0.958 rs1414199 chr6:86522370 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs26868 0.816 rs26872 chr16:2247644 C/T cg25665528 chr16:2260870 C16orf79 -0.31 -4.81 -0.4 4.38e-6 Height; TGCT cis rs3892630 0.878 rs1061686 chr19:33204544 C/T cg22980127 chr19:33182716 NUDT19 -0.62 -5.07 -0.41 1.41e-6 Red blood cell traits; TGCT cis rs9513593 1.000 rs7323390 chr13:99997968 A/G cg21788972 chr13:99853209 UBAC2 0.56 4.5 0.37 1.52e-5 Psoriasis; TGCT cis rs6565180 0.926 rs4787643 chr16:30393660 G/A cg17640201 chr16:30407289 ZNF48 0.96 9.04 0.63 2.57e-15 Tonsillectomy; TGCT cis rs9911578 1.000 rs2270097 chr17:56572070 G/A cg12560992 chr17:57184187 TRIM37 -0.76 -9.14 -0.63 1.48e-15 Intelligence (multi-trait analysis); TGCT cis rs17030434 0.953 rs10010787 chr4:154692059 G/A cg14289246 chr4:154710475 SFRP2 -0.96 -7.81 -0.57 2.06e-12 Electrocardiographic conduction measures; TGCT cis rs9534288 0.619 rs2146881 chr13:46679598 T/C cg15192986 chr13:46630673 CPB2 -0.47 -5.61 -0.45 1.26e-7 Blood protein levels; TGCT cis rs651907 0.535 rs17347156 chr3:101504674 G/A cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.31 -0.49 4.5e-9 Colorectal cancer; TGCT cis rs7727544 0.582 rs10478998 chr5:131516531 G/A cg24060327 chr5:131705240 SLC22A5 -0.45 -4.5 -0.37 1.55e-5 Blood metabolite levels; TGCT cis rs372883 0.600 rs407712 chr21:30722531 G/A cg24692254 chr21:30365293 RNF160 -0.54 -4.83 -0.4 3.97e-6 Pancreatic cancer; TGCT cis rs295140 0.507 rs1369842 chr2:201108987 C/A cg23649088 chr2:200775458 C2orf69 -0.29 -4.92 -0.4 2.68e-6 QT interval; TGCT cis rs2952156 0.684 rs1877031 chr17:37814080 G/A cg00129232 chr17:37814104 STARD3 -0.22 -4.48 -0.37 1.68e-5 Asthma; TGCT cis rs79387448 0.745 rs2310294 chr2:103165706 A/G cg09003973 chr2:102972529 NA 0.93 6.03 0.48 1.73e-8 Gut microbiota (bacterial taxa); TGCT cis rs9393692 0.905 rs7746807 chr6:26293338 C/A cg00631329 chr6:26305371 NA -0.42 -6.22 -0.49 6.83e-9 Educational attainment; TGCT cis rs854765 0.964 rs2230316 chr17:17997209 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.61 -5.8 -0.46 5.24e-8 Total body bone mineral density; TGCT cis rs8017423 0.967 rs11849641 chr14:90727647 T/C cg04374321 chr14:90722782 PSMC1 0.76 7.63 0.57 5.3e-12 Mortality in heart failure; TGCT cis rs9372498 0.536 rs72969531 chr6:118729974 C/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs10769945 0.730 rs217208 chr11:1974892 C/G cg18032502 chr11:1949113 TNNT3 -0.24 -4.45 -0.37 1.9e-5 DNA methylation (variation); TGCT cis rs9556958 0.708 rs4772092 chr13:99166614 A/G cg07423050 chr13:99094983 FARP1 -0.23 -4.87 -0.4 3.38e-6 Educational attainment (years of education); TGCT cis rs1532993 0.518 rs10019787 chr4:98629088 C/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs17152411 0.843 rs7896051 chr10:126583119 T/C cg07906193 chr10:126599966 NA 0.43 5.25 0.43 6.46e-7 Height; TGCT cis rs208520 0.507 rs7755710 chr6:66783355 G/A cg07460842 chr6:66804631 NA -1.08 -15.95 -0.82 8.03e-32 Exhaled nitric oxide output; TGCT cis rs7666738 0.927 rs4699328 chr4:99055890 C/T cg17366294 chr4:99064904 C4orf37 0.69 6.9 0.53 2.33e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6952808 0.798 rs28970524 chr7:1927484 C/T cg04267008 chr7:1944627 MAD1L1 -0.34 -4.59 -0.38 1.08e-5 Bipolar disorder and schizophrenia; TGCT cis rs7805747 0.961 rs17173238 chr7:151406220 A/G cg17611936 chr7:151411526 PRKAG2 0.5 6.54 0.51 1.43e-9 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs7582180 0.629 rs11123826 chr2:100936276 G/T cg08017756 chr2:100939284 LONRF2 0.28 4.62 0.38 9.58e-6 Intelligence (multi-trait analysis); TGCT cis rs11167764 0.945 rs13161849 chr5:141473395 A/G cg08523384 chr5:141488047 NDFIP1 -0.24 -4.91 -0.4 2.85e-6 Crohn's disease; TGCT cis rs9467773 1.000 rs12526680 chr6:26550954 A/G cg15659132 chr6:26577336 NA 0.89 13.12 0.76 3.43e-25 Intelligence (multi-trait analysis); TGCT cis rs9549367 0.673 rs3751413 chr13:113854715 C/T cg09473364 chr13:112927190 NA 0.3 4.68 0.39 7.49e-6 Platelet distribution width; TGCT cis rs2046867 0.818 rs62249875 chr3:72911858 G/A cg25664220 chr3:72788482 NA -0.54 -7.27 -0.55 3.61e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs11785400 1.000 rs11785400 chr8:143730456 C/T cg24634471 chr8:143751801 JRK 0.54 5.85 0.46 4.19e-8 Schizophrenia; TGCT cis rs7267979 0.932 rs433352 chr20:25467992 C/T cg16686733 chr20:25566563 NINL -0.57 -5.75 -0.46 6.6e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs74233809 1.000 rs12413046 chr10:104871204 A/G cg05855489 chr10:104503620 C10orf26 0.84 4.47 0.37 1.71e-5 Birth weight; TGCT cis rs981844 0.683 rs1563462 chr4:154755051 G/A cg14289246 chr4:154710475 SFRP2 -1.0 -9.01 -0.63 3.04e-15 Response to statins (LDL cholesterol change); TGCT cis rs1801251 0.896 rs2197563 chr2:233687080 G/A cg08000102 chr2:233561755 GIGYF2 -0.59 -6.19 -0.49 7.93e-9 Coronary artery disease; TGCT cis rs4849845 0.637 rs4849851 chr2:121055910 A/C cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs9633740 1.000 rs7896832 chr10:82257570 T/C cg01528321 chr10:82214614 TSPAN14 1.03 8.42 0.6 7.78e-14 Post bronchodilator FEV1; TGCT cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg03806693 chr22:41940476 POLR3H -1.14 -12.97 -0.76 7.76e-25 Vitiligo; TGCT cis rs789852 0.867 rs1773175 chr3:194317732 G/A cg18000598 chr3:194342907 TMEM44 -0.76 -5.1 -0.42 1.25e-6 QT interval; TGCT cis rs2657888 0.965 rs2657903 chr12:56933722 G/A cg23932658 chr12:57637574 STAC3 0.48 4.57 0.38 1.18e-5 Adiponectin levels; TGCT cis rs6424115 0.830 rs6424119 chr1:24204143 A/G cg15997130 chr1:24165203 NA 0.85 8.93 0.63 4.81e-15 Immature fraction of reticulocytes; TGCT cis rs67311347 1.000 rs954589 chr3:40444545 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg11941060 chr3:133502564 NA -0.26 -5.32 -0.43 4.74e-7 Iron status biomarkers; TGCT cis rs473651 0.904 rs508274 chr2:239337723 G/A cg08773314 chr2:239334832 ASB1 0.47 7.87 0.58 1.54e-12 Multiple system atrophy; TGCT cis rs2204008 0.569 rs11495449 chr12:37995753 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.22 0.42 7.4e-7 Bladder cancer; TGCT cis rs9393692 0.905 rs7769028 chr6:26267568 C/T cg00631329 chr6:26305371 NA -0.43 -6.41 -0.5 2.72e-9 Educational attainment; TGCT cis rs2742417 1.000 rs2673065 chr3:45771222 C/T cg04837898 chr3:45731254 SACM1L -0.53 -5.53 -0.45 1.78e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs28595532 0.920 rs114262028 chr4:119734877 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs12477438 0.798 rs6542849 chr2:99578493 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.95 10.14 0.67 5.89e-18 Intelligence (multi-trait analysis); TGCT trans rs11764590 0.715 rs11766468 chr7:2082604 G/A cg25206134 chr2:45395956 NA 0.97 6.73 0.52 5.68e-10 Neuroticism; TGCT cis rs8072100 0.817 rs12449647 chr17:45548958 C/A cg08085267 chr17:45401833 C17orf57 -0.47 -5.14 -0.42 1.05e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4555082 0.874 rs11622166 chr14:105759763 C/A cg01266790 chr14:105781312 PACS2 0.56 4.64 0.38 8.89e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs1218582 0.688 rs58629129 chr1:154910930 T/C cg16680214 chr1:154839983 KCNN3 -0.38 -8.26 -0.6 1.85e-13 Prostate cancer; TGCT cis rs4242434 0.819 rs1871902 chr8:22470710 G/A cg03733263 chr8:22462867 KIAA1967 1.08 17.08 0.84 2.28e-34 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7582180 0.700 rs11685401 chr2:100976685 A/G cg14675211 chr2:100938903 LONRF2 0.47 4.6 0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.660 rs112560929 chr1:46822297 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs589448 0.902 rs2603090 chr12:69777188 G/A cg20891283 chr12:69753455 YEATS4 0.91 10.46 0.68 9.81e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs7208859 0.623 rs11651857 chr17:28926362 G/T cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4253772 0.513 rs9615345 chr22:46713631 C/T cg24881330 chr22:46731750 TRMU 0.94 6.05 0.48 1.58e-8 LDL cholesterol;Cholesterol, total; TGCT cis rs1552244 0.608 rs7615408 chr3:10000186 A/G cg00149659 chr3:10157352 C3orf10 0.67 4.91 0.4 2.85e-6 Alzheimer's disease; TGCT cis rs17152411 1.000 rs12355869 chr10:126645231 G/T cg07906193 chr10:126599966 NA 0.41 5.11 0.42 1.18e-6 Height; TGCT cis rs707040 0.921 rs719461 chr2:155230619 T/C cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs5769765 0.908 rs9627788 chr22:50300438 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.36 5.13 0.42 1.08e-6 Schizophrenia; TGCT cis rs11098499 0.722 rs17595727 chr4:120262074 C/T cg09307838 chr4:120376055 NA -0.54 -5.17 -0.42 9.29e-7 Corneal astigmatism; TGCT cis rs57590327 0.679 rs34674953 chr3:81605113 T/G cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs1371867 0.875 rs1660344 chr8:101324659 A/G cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs1403694 0.695 rs11927941 chr3:186433046 A/G cg12454167 chr3:186435060 KNG1 0.5 8.56 0.61 3.65e-14 Blood protein levels; TGCT cis rs1008375 0.646 rs13103430 chr4:17567355 A/C cg16339924 chr4:17578868 LAP3 -0.69 -5.59 -0.45 1.35e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs601339 1.000 rs1798219 chr12:123180061 A/C cg11919336 chr12:123188078 GPR109A 0.64 7.86 0.58 1.61e-12 Adiponectin levels; TGCT cis rs9868809 0.505 rs13063223 chr3:48750340 G/A cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.93 0.47 2.78e-8 Bipolar disorder; TGCT cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.66 6.16 0.48 9.18e-9 Bipolar disorder; TGCT cis rs7959452 0.535 rs7133487 chr12:69774377 G/A cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs7666738 0.830 rs62318504 chr4:98935558 T/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7617773 0.780 rs3731550 chr3:48206583 A/C cg11946769 chr3:48343235 NME6 0.73 6.33 0.49 4.03e-9 Coronary artery disease; TGCT cis rs6921919 0.583 rs1591913 chr6:28351728 C/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.3 -0.43 5.13e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9486719 0.749 rs1009596 chr6:96843688 A/G cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs11690935 0.959 rs10166005 chr2:172607294 C/T cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs35146811 0.625 rs2906645 chr7:99817859 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs6921919 0.583 rs9461459 chr6:28361916 T/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7552404 1.000 rs7548962 chr1:76139266 G/A cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs427394 0.582 rs274662 chr5:6704860 G/A cg10857441 chr5:6722123 POLS -0.29 -6.21 -0.49 7.15e-9 Menopause (age at onset); TGCT cis rs1218582 0.772 rs2335408 chr1:154915977 G/A cg16680214 chr1:154839983 KCNN3 -0.35 -7.15 -0.54 6.42e-11 Prostate cancer; TGCT cis rs4988958 0.584 rs7559845 chr2:103046214 T/G cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs1552244 0.554 rs6762594 chr3:9995516 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.32 -4.84 -0.4 3.76e-6 Alzheimer's disease; TGCT cis rs896854 0.530 rs10956934 chr8:95992473 C/A cg13393036 chr8:95962371 TP53INP1 -0.58 -7.01 -0.53 1.36e-10 Type 2 diabetes; TGCT cis rs11779988 0.501 rs3760 chr8:17886345 T/C cg01800426 chr8:17659068 MTUS1 -0.68 -5.48 -0.44 2.32e-7 Breast cancer; TGCT cis rs617219 0.737 rs6453431 chr5:78493873 G/C cg23514016 chr5:78407564 BHMT 0.34 5.15 0.42 9.87e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4824093 0.610 rs4824113 chr22:50284974 C/T cg20569369 chr22:51173646 NA 0.29 4.74 0.39 5.73e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs16966142 1.000 rs16966142 chr16:89851033 C/T cg26513180 chr16:89883248 FANCA 1.02 5.54 0.45 1.73e-7 Caffeine consumption; TGCT cis rs7666738 0.830 rs1120708 chr4:98931260 G/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11992186 0.570 rs17628941 chr8:8587534 G/C cg15556689 chr8:8085844 FLJ10661 -0.56 -4.69 -0.39 7.07e-6 Neuroticism; TGCT cis rs75804782 0.557 rs3769118 chr2:239342542 C/G cg18131467 chr2:239335373 ASB1 -0.71 -4.44 -0.37 1.98e-5 Morning vs. evening chronotype;Chronotype; TGCT trans rs4650994 0.525 rs2493864 chr1:178545003 A/C cg05059571 chr16:84539110 KIAA1609 -0.52 -10.29 -0.68 2.45e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4727027 0.901 rs66800495 chr7:148763702 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.97 0.41 2.22e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4460629 0.742 rs6693477 chr1:155081940 A/G cg23973274 chr1:155060172 NA -0.28 -5.13 -0.42 1.07e-6 Serum magnesium levels; TGCT cis rs1682825 0.858 rs58731244 chr3:10756497 G/A cg23512531 chr3:10780469 NA 0.62 4.53 0.38 1.36e-5 Economic and political preferences (feminism/equality); TGCT cis rs2463822 0.687 rs118012228 chr11:62155914 G/A cg06239285 chr11:62104954 ASRGL1 -0.94 -6.61 -0.51 1.03e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2730260 0.537 rs73169246 chr7:158890593 C/T cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs12464483 0.556 rs2609934 chr2:30895979 G/A cg12454169 chr2:30669597 LCLAT1 0.45 5.03 0.41 1.67e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs1799949 0.965 rs799912 chr17:41257134 T/C cg10047753 chr17:41438598 NA 0.73 6.97 0.53 1.64e-10 Menopause (age at onset); TGCT cis rs4654899 0.758 rs12137408 chr1:21282945 A/G cg01072550 chr1:21505969 NA -0.55 -8.89 -0.62 6.13e-15 Superior frontal gyrus grey matter volume; TGCT cis rs9787249 0.957 rs11809515 chr1:40205326 C/A cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs12367572 0.965 rs7952764 chr12:45246211 C/A cg04608330 chr12:45269318 NELL2 -0.65 -6.96 -0.53 1.74e-10 Gut microbiome composition (summer); TGCT cis rs6089829 0.926 rs6062395 chr20:61667904 A/G cg08564027 chr20:61660810 NA 0.36 6.66 0.51 7.9e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg24549020 chr5:56110836 MAP3K1 0.68 5.89 0.47 3.46e-8 Initial pursuit acceleration; TGCT cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.64 7.0 0.53 1.43e-10 Blood metabolite levels; TGCT cis rs2268667 0.647 rs11161609 chr1:85862736 G/T cg16011679 chr1:85725395 C1orf52 -0.51 -4.62 -0.38 9.51e-6 Asymmetrical dimethylarginine levels; TGCT cis rs11574514 1.000 rs10775302 chr16:67792439 C/T cg00545966 chr16:67701244 C16orf86;C16orf48 0.73 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs7954584 0.567 rs11043243 chr12:122356370 G/C cg21171335 chr12:122356390 WDR66 0.7 7.02 0.53 1.25e-10 Mean corpuscular volume; TGCT cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg18654377 chr3:49208889 KLHDC8B -0.44 -5.85 -0.47 4.09e-8 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg03264133 chr6:25882463 NA -0.51 -5.37 -0.43 3.77e-7 Blood metabolite levels; TGCT cis rs6598955 0.671 rs11247914 chr1:26648838 G/T cg04990556 chr1:26633338 UBXN11 0.65 4.59 0.38 1.06e-5 Obesity-related traits; TGCT cis rs62244186 0.566 rs6766221 chr3:44882784 C/T cg10263370 chr3:44754102 ZNF502 -0.47 -5.67 -0.45 9.47e-8 Depressive symptoms; TGCT cis rs12971120 0.838 rs747176 chr18:72154931 G/A cg26446133 chr18:72167187 CNDP2 -0.36 -6.38 -0.5 3.22e-9 Refractive error; TGCT cis rs7429990 0.965 rs11709289 chr3:47806649 G/A cg11946769 chr3:48343235 NME6 0.59 4.44 0.37 1.95e-5 Educational attainment (years of education); TGCT cis rs5769765 1.000 rs738711 chr22:50282603 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.81 0.73 5.03e-22 Schizophrenia; TGCT cis rs1008375 0.966 rs3733576 chr4:17586703 T/C cg16339924 chr4:17578868 LAP3 0.83 7.21 0.54 4.92e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9473924 0.505 rs9473921 chr6:50828072 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs2191566 1.000 rs10418363 chr19:44525463 A/G cg03039196 chr19:44506973 ZNF230 0.55 4.77 0.39 5.16e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs6547741 1.000 rs76784350 chr2:27764278 A/G cg27432699 chr2:27873401 GPN1 0.18 4.44 0.37 1.96e-5 Oral cavity cancer; TGCT cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs7909074 1.000 rs10751361 chr10:45398186 C/A cg05187965 chr10:45406764 TMEM72 -0.25 -5.3 -0.43 5.07e-7 Mean corpuscular volume; TGCT cis rs6433895 1.000 rs7598960 chr2:182018382 T/G cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT cis rs2985684 0.841 rs12894785 chr14:50049755 G/C cg04989706 chr14:50066350 PPIL5 -0.53 -4.47 -0.37 1.74e-5 Carotid intima media thickness; TGCT cis rs7666738 0.519 rs13136069 chr4:98819568 C/T cg18180107 chr4:99064573 C4orf37 0.54 4.61 0.38 9.77e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3820928 0.874 rs6706802 chr2:227850776 A/G cg11843606 chr2:227700838 RHBDD1 -0.5 -4.48 -0.37 1.7e-5 Pulmonary function; TGCT cis rs7829975 0.536 rs2980439 chr8:8094870 G/A cg15556689 chr8:8085844 FLJ10661 0.86 8.87 0.62 6.54e-15 Mood instability; TGCT cis rs7412746 0.658 rs11204723 chr1:150731618 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.08 0.42 1.33e-6 Melanoma; TGCT cis rs4149178 0.656 rs9472032 chr6:43294041 C/A cg07522644 chr6:43142093 SRF 0.66 4.69 0.39 7e-6 Urate levels; TGCT cis rs7208859 0.573 rs73267865 chr17:29064204 C/G cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12291225 0.679 rs11605531 chr11:14291594 A/G cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs929354 0.742 rs7801905 chr7:156940111 T/C cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs9303401 0.527 rs12939313 chr17:56755616 A/T cg10487724 chr17:56770010 TEX14;RAD51C 0.61 5.41 0.44 3.12e-7 Cognitive test performance; TGCT cis rs7923609 0.811 rs10822181 chr10:65325126 G/A cg08743896 chr10:65200160 JMJD1C 0.33 4.49 0.37 1.6e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs7523273 0.586 rs2796276 chr1:207951513 G/A cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs9611565 0.503 rs5751156 chr22:42170025 A/G cg03806693 chr22:41940476 POLR3H 1.01 10.26 0.68 3.04e-18 Vitiligo; TGCT cis rs28456 1 rs28456 chr11:61589481 A/G cg01500311 chr11:61656094 FADS3 -0.29 -4.98 -0.41 2.1e-6 Bipolar disorder; TGCT cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs9325144 0.534 rs1973293 chr12:38679575 C/T cg26384229 chr12:38710491 ALG10B 0.67 6.42 0.5 2.56e-9 Morning vs. evening chronotype; TGCT cis rs7635838 0.686 rs347589 chr3:11288419 A/G cg00170343 chr3:11313890 ATG7 0.68 6.6 0.51 1.06e-9 HDL cholesterol; TGCT cis rs4409675 0.576 rs7520860 chr1:28232952 C/A cg23691781 chr1:28212827 C1orf38 0.26 5.44 0.44 2.76e-7 Corneal astigmatism; TGCT cis rs9325144 0.560 rs10785562 chr12:38637419 A/C cg26384229 chr12:38710491 ALG10B -0.64 -5.82 -0.46 4.63e-8 Morning vs. evening chronotype; TGCT cis rs6582630 0.638 rs10880644 chr12:38554959 G/A cg26384229 chr12:38710491 ALG10B 0.52 4.74 0.39 5.65e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6901004 0.803 rs9400470 chr6:111478131 T/C cg15721981 chr6:111408429 SLC16A10 -0.51 -4.53 -0.38 1.35e-5 Blood metabolite levels; TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg22166914 chr1:53195759 ZYG11B 0.3 4.95 0.41 2.41e-6 Monocyte count; TGCT cis rs1552244 0.554 rs6786636 chr3:10045703 T/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs6582630 0.502 rs1607876 chr12:38355750 T/C cg26384229 chr12:38710491 ALG10B 0.77 6.73 0.52 5.54e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs7772486 0.641 rs2253757 chr6:146199686 C/T cg23711669 chr6:146136114 FBXO30 0.76 7.12 0.54 7.5e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs597539 0.616 rs513476 chr11:68698996 C/T cg06028808 chr11:68637592 NA 0.53 6.86 0.52 2.89e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs7615952 1.000 rs7616044 chr3:125649354 G/C cg07211511 chr3:129823064 LOC729375 -0.46 -7.65 -0.57 4.78e-12 Blood pressure (smoking interaction); TGCT cis rs2456568 0.835 rs1518578 chr11:93656854 G/T cg16099599 chr11:93583650 C11orf90 -0.43 -5.09 -0.42 1.27e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs7216064 1.000 rs9912770 chr17:65868233 C/T cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg08280861 chr8:58055591 NA 0.46 6.87 0.52 2.81e-10 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.559 rs6121243 chr20:30415094 C/G cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs9818758 0.607 rs9855123 chr3:49229457 C/T cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9486719 0.895 rs12527021 chr6:97025496 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.52 4.87 0.4 3.3e-6 Prudent dietary pattern; TGCT cis rs13191362 0.507 rs2155506 chr6:163035342 G/A cg06582575 chr6:163149167 PACRG;PARK2 -0.58 -5.73 -0.46 7.06e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs2688608 0.592 rs11814282 chr10:75490217 T/C cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs28595532 0.920 rs114544767 chr4:119728364 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs9913156 0.793 rs72835633 chr17:4562643 C/T cg23387401 chr17:4582204 PELP1 0.31 4.57 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs66561647 0.661 rs7387614 chr8:128929353 C/T cg11792826 chr8:129160931 MIR1208 0.22 5.08 0.42 1.34e-6 Hemoglobin concentration; TGCT cis rs35883536 0.647 rs1335765 chr1:101048612 A/T cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs10875746 0.855 rs73102065 chr12:48492607 T/C cg20731937 chr12:48336164 NA 0.63 4.96 0.41 2.24e-6 Longevity (90 years and older); TGCT cis rs72627509 0.523 rs12650282 chr4:57733604 A/G cg26694713 chr4:57773883 REST -0.57 -5.81 -0.46 4.95e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs11264213 0.591 rs603945 chr1:36490186 C/T cg27506609 chr1:36549197 TEKT2 -0.31 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT cis rs7104764 0.507 rs7111364 chr11:258542 G/C cg18336825 chr11:236787 PSMD13;SIRT3 0.76 5.68 0.45 8.96e-8 Menarche (age at onset); TGCT cis rs28830936 0.625 rs8038764 chr15:41907905 A/C cg17847044 chr15:42102381 MAPKBP1 0.19 5.35 0.43 4.08e-7 Diastolic blood pressure; TGCT cis rs4988958 0.584 rs7589142 chr2:103024660 T/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs6908034 0.556 rs7750703 chr6:19804814 C/G cg02682789 chr6:19804855 NA 0.92 5.24 0.43 6.7e-7 Endometriosis;Deep ovarian and/or rectovaginal disease with dense adhesions; TGCT cis rs6684514 1.000 rs10908496 chr1:156264000 G/A cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1406084 0.576 rs7604919 chr2:154727550 G/C cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 1.000 rs9461271 chr6:26554968 G/A cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs937254 0.866 rs2453088 chr15:57872653 G/T cg05276753 chr15:57844149 NA 0.31 4.48 0.37 1.67e-5 HDL cholesterol; TGCT cis rs9467603 0.547 rs4712936 chr6:25417423 G/T cg16898833 chr6:26189333 HIST1H4D -1.26 -5.08 -0.42 1.35e-6 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.841 rs115987912 chr4:119737085 C/T cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs13033859 0.526 rs12477065 chr2:292753 C/T cg26211041 chr2:776598 NA -0.27 -4.45 -0.37 1.9e-5 Mitochondrial DNA levels; TGCT cis rs7223966 1.000 rs8078462 chr17:61857937 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2921073 0.509 rs2976931 chr8:8257317 C/A cg08975724 chr8:8085496 FLJ10661 0.56 5.01 0.41 1.82e-6 Parkinson's disease; TGCT cis rs3733585 0.673 rs4467563 chr4:9953460 A/T cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7954584 0.567 rs1720033 chr12:122384344 C/T cg22618164 chr12:122356400 WDR66 -0.7 -6.91 -0.53 2.23e-10 Mean corpuscular volume; TGCT cis rs7584330 0.554 rs74001384 chr2:238424530 T/C cg08992911 chr2:238395768 MLPH 0.73 5.01 0.41 1.85e-6 Prostate cancer; TGCT cis rs7572733 0.534 rs1435568 chr2:198762879 T/C cg00792783 chr2:198669748 PLCL1 0.57 5.2 0.42 8.09e-7 Dermatomyositis; TGCT cis rs35306767 0.953 rs11253520 chr10:975961 C/G cg20503657 chr10:835505 NA -0.43 -5.89 -0.47 3.42e-8 Eosinophil percentage of granulocytes; TGCT cis rs801193 0.967 rs2420827 chr7:66147101 G/A cg18876405 chr7:65276391 NA -0.38 -5.83 -0.46 4.44e-8 Aortic root size; TGCT trans rs1974653 0.672 rs9606240 chr22:20071423 A/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs941873 0.900 rs4979861 chr10:81131595 A/G cg09469691 chr10:81107165 PPIF 0.63 6.38 0.5 3.26e-9 Height; TGCT cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4072705 0.646 rs915032 chr9:127245682 G/C cg13476313 chr9:127244764 NR5A1 0.31 5.09 0.42 1.29e-6 Menarche (age at onset); TGCT cis rs12220238 1.000 rs11000890 chr10:75904073 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2980439 0.870 rs2945230 chr8:8109936 A/G cg15556689 chr8:8085844 FLJ10661 0.72 6.38 0.5 3.13e-9 Neuroticism; TGCT cis rs17270561 0.541 rs17586946 chr6:25939053 C/T cg17042849 chr6:26104293 HIST1H4C -0.8 -5.68 -0.45 9.14e-8 Iron status biomarkers; TGCT cis rs2486012 1.000 rs3011227 chr1:44325409 G/A cg12908607 chr1:44402522 ARTN -0.69 -5.59 -0.45 1.36e-7 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs1044826 0.642 rs9833307 chr3:139181370 G/A cg00490450 chr3:139108681 COPB2 0.52 4.53 0.38 1.39e-5 Obesity-related traits; TGCT cis rs6671200 0.541 rs3738170 chr1:95699604 G/C cg06440946 chr1:95699313 RWDD3 -0.62 -5.26 -0.43 6.12e-7 Stearic acid (18:0) levels; TGCT cis rs4862750 0.872 rs6811837 chr4:187898162 G/A cg03452623 chr4:187889614 NA -0.36 -5.34 -0.43 4.32e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs17345786 0.861 rs11707689 chr3:101086475 A/G cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs6722750 0.840 rs6712700 chr2:64374041 A/G cg22352474 chr2:64371530 PELI1 0.73 7.09 0.54 9.04e-11 Neuroticism; TGCT cis rs2486012 1.000 rs2906461 chr1:44334228 G/C cg12908607 chr1:44402522 ARTN -0.72 -5.68 -0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs9300255 0.602 rs884548 chr12:123634122 A/G cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs7829975 1.000 rs7829975 chr8:8548117 T/A cg06636001 chr8:8085503 FLJ10661 -0.69 -5.94 -0.47 2.67e-8 Mood instability; TGCT trans rs210152 0.588 rs3119024 chr6:33450034 T/C cg08795360 chr21:41033440 B3GALT5 -0.45 -7.11 -0.54 8.23e-11 Schizophrenia; TGCT cis rs3540 0.513 rs2601181 chr15:90924702 C/T cg22089800 chr15:90895588 ZNF774 0.82 9.04 0.63 2.61e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2836950 0.502 rs12627205 chr21:40630027 C/T cg17971929 chr21:40555470 PSMG1 -0.54 -4.87 -0.4 3.36e-6 Menarche (age at onset); TGCT cis rs35146811 0.700 rs866500 chr7:99840461 A/G cg22906224 chr7:99728672 NA -0.51 -4.59 -0.38 1.08e-5 Coronary artery disease; TGCT cis rs9325144 0.555 rs6582576 chr12:38701230 C/T cg26384229 chr12:38710491 ALG10B -0.61 -5.83 -0.46 4.42e-8 Morning vs. evening chronotype; TGCT cis rs7586879 0.593 rs11689543 chr2:25130440 A/T cg15423357 chr2:25149977 NA 0.5 4.88 0.4 3.13e-6 Body mass index; TGCT cis rs9814567 1.000 rs9990351 chr3:134239191 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.92 9.3 0.64 6.19e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4851266 1.000 rs4851264 chr2:100810188 T/C cg22139774 chr2:100720529 AFF3 -0.35 -5.23 -0.43 6.99e-7 Educational attainment; TGCT cis rs5750830 0.649 rs4821895 chr22:39823015 A/G cg24399712 chr22:39784796 NA -1.06 -12.45 -0.75 1.37e-23 Intelligence (multi-trait analysis); TGCT cis rs1997103 1.000 rs6953509 chr7:55412179 G/A cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs12477438 0.520 rs8179690 chr2:99795300 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -1.06 -13.07 -0.76 4.41e-25 Chronic sinus infection; TGCT cis rs10871290 0.881 rs11649338 chr16:74471420 C/T cg01733217 chr16:74700730 RFWD3 -0.57 -5.46 -0.44 2.54e-7 Breast cancer; TGCT cis rs6582630 0.537 rs1829579 chr12:38420555 A/G cg13010199 chr12:38710504 ALG10B 0.59 4.79 0.4 4.67e-6 Drug-induced liver injury (flucloxacillin); TGCT trans rs7618501 0.633 rs11925192 chr3:50038664 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.41 0.65 3.39e-16 Intelligence (multi-trait analysis); TGCT cis rs1878931 0.501 rs9635547 chr16:3416664 C/T cg05754148 chr16:3507555 NAT15 -0.33 -4.6 -0.38 1.02e-5 Body mass index (adult); TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 15.82 0.82 1.53e-31 Prudent dietary pattern; TGCT cis rs1371867 0.846 rs1660326 chr8:101290447 G/A cg06636551 chr8:101224915 SPAG1 -0.5 -6.88 -0.53 2.61e-10 Atrioventricular conduction; TGCT cis rs4900538 0.927 rs8005804 chr14:102957803 A/G cg18135206 chr14:102964638 TECPR2 0.21 5.13 0.42 1.08e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs1552244 0.572 rs58223482 chr3:10169746 G/C cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs9486719 0.895 rs11152960 chr6:96900398 A/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs2228479 0.850 rs2238531 chr16:89856217 C/G cg06558623 chr16:89946397 TCF25 0.47 4.58 0.38 1.14e-5 Skin colour saturation; TGCT cis rs2180341 1.000 rs4895822 chr6:127642703 T/C cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs2153535 0.580 rs7766852 chr6:8472417 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.16e-8 Motion sickness; TGCT cis rs1670533 0.615 rs59985183 chr4:1087171 G/T cg27284194 chr4:1044797 NA 0.66 5.85 0.46 4.16e-8 Recombination rate (females); TGCT cis rs1903068 0.657 rs10026340 chr4:55998136 G/A cg09978860 chr4:56023921 NA 0.54 5.66 0.45 9.93e-8 Endometriosis; TGCT cis rs208520 0.690 rs1885100 chr6:66871047 C/G cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs8013055 0.796 rs11628497 chr14:105970789 C/T cg19700328 chr14:106028568 NA -0.54 -5.92 -0.47 3e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7819412 0.617 rs10087081 chr8:10974917 C/T cg21775007 chr8:11205619 TDH -0.5 -4.85 -0.4 3.59e-6 Triglycerides; TGCT cis rs6570726 0.818 rs9390338 chr6:145908265 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.28 0.64 7.13e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7523273 0.586 rs2724359 chr1:207935706 A/G cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs7267979 0.866 rs2424699 chr20:25257462 G/A cg14121845 chr20:25566513 NINL 0.55 5.95 0.47 2.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9549367 0.789 rs12866090 chr13:113869410 G/A cg00898013 chr13:113819073 PROZ -0.4 -4.92 -0.4 2.75e-6 Platelet distribution width; TGCT cis rs9952991 0.941 rs8096138 chr18:12808140 C/G cg24737193 chr18:12778029 NA -0.52 -5.43 -0.44 2.85e-7 Inflammatory skin disease; TGCT cis rs308403 0.509 rs7690409 chr4:123666757 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.84 0.73 4.22e-22 Blood protein levels; TGCT cis rs7666738 0.791 rs2903142 chr4:99040071 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 0.730 rs55759249 chr17:57027135 A/G cg12560992 chr17:57184187 TRIM37 -0.74 -7.04 -0.53 1.18e-10 Intelligence (multi-trait analysis); TGCT trans rs9951602 0.512 rs7240758 chr18:76650677 T/C cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs4689388 0.750 rs10001190 chr4:6284633 C/T cg25554036 chr4:6271136 WFS1 -0.55 -7.72 -0.57 3.32e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7666738 0.830 rs3907021 chr4:99038668 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9311474 0.713 rs352167 chr3:52238656 C/T cg07507251 chr3:52567010 NT5DC2 -0.39 -5.03 -0.41 1.7e-6 Electroencephalogram traits; TGCT cis rs17221829 0.733 rs11018699 chr11:89379962 A/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs13256369 0.802 rs12681326 chr8:8566389 G/A cg18904891 chr8:8559673 CLDN23 0.58 5.4 0.44 3.29e-7 Obesity-related traits; TGCT trans rs2760061 0.819 rs3094914 chr1:228206934 C/T cg16006296 chr10:38738647 LOC399744 -0.31 -7.12 -0.54 7.75e-11 Diastolic blood pressure; TGCT cis rs986417 1.000 rs1956555 chr14:60968804 A/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs981844 0.725 rs872453 chr4:154727131 T/C cg14289246 chr4:154710475 SFRP2 1.04 9.67 0.66 8.17e-17 Response to statins (LDL cholesterol change); TGCT cis rs929354 1.000 rs1182384 chr7:157040642 A/G cg05182265 chr7:156933206 UBE3C 0.3 6.31 0.49 4.59e-9 Body mass index; TGCT cis rs16958440 0.867 rs79275306 chr18:44711620 G/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 5.11 0.42 1.19e-6 Schizophrenia; TGCT cis rs3820068 0.580 rs12747696 chr1:16002978 A/G cg05660106 chr1:15850417 CASP9 0.65 5.82 0.46 4.66e-8 Systolic blood pressure; TGCT cis rs5769707 0.777 rs739243 chr22:50057211 C/T cg05373962 chr22:49881684 NA -0.31 -6.13 -0.48 1.1e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4665809 0.652 rs2384360 chr2:26405016 C/G cg04944784 chr2:26401820 FAM59B -0.76 -6.34 -0.49 3.94e-9 Gut microbiome composition (summer); TGCT cis rs11122272 0.705 rs2790879 chr1:231534389 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.22 -0.49 6.99e-9 Hemoglobin concentration; TGCT cis rs12291225 0.679 rs11238 chr11:14288128 A/C cg19336497 chr11:14380999 RRAS2 0.39 6.01 0.47 1.96e-8 Sense of smell; TGCT cis rs854765 0.583 rs8065970 chr17:17858771 A/G cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs4742903 0.967 rs7048372 chr9:106859738 T/C cg21169611 chr9:106856078 SMC2 0.49 4.6 0.38 1.03e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs10465746 0.967 rs11163861 chr1:84354282 T/C cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg14004847 chr7:1930337 MAD1L1 -0.27 -4.68 -0.39 7.35e-6 Schizophrenia; TGCT cis rs10876993 0.893 rs1678504 chr12:58085498 G/C cg15848620 chr12:58087721 OS9 -0.73 -5.95 -0.47 2.56e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg06481639 chr22:41940642 POLR3H -0.74 -6.55 -0.51 1.41e-9 Vitiligo; TGCT cis rs568617 0.716 rs17854357 chr11:65601560 G/C cg04055107 chr11:65626734 MUS81;CFL1 0.72 5.5 0.44 2.06e-7 Crohn's disease; TGCT cis rs72615157 0.697 rs2056726 chr7:99780283 G/A cg00814883 chr7:100076585 TSC22D4 -0.53 -4.97 -0.41 2.19e-6 Lung function (FEV1/FVC); TGCT cis rs6912958 1.000 rs6937823 chr6:88160386 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.64 -6.31 -0.49 4.58e-9 Monocyte percentage of white cells; TGCT cis rs2204008 0.743 rs2127952 chr12:37995364 G/T cg13010199 chr12:38710504 ALG10B 0.61 4.89 0.4 3.05e-6 Bladder cancer; TGCT cis rs1461503 0.966 rs7113725 chr11:122843511 G/T cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs477895 1.000 rs34292685 chr11:64049021 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.67 5.18 0.42 8.68e-7 Mean platelet volume; TGCT cis rs9527 0.590 rs7067663 chr10:104883650 A/G cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs1365505 0.600 rs1648350 chr15:50486400 G/A cg26188685 chr15:50540269 HDC -0.4 -6.9 -0.53 2.39e-10 Blood metabolite ratios; TGCT cis rs8062405 0.964 rs9972768 chr16:28861734 A/C cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7267979 1.000 rs2387881 chr20:25378172 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7209700 0.742 rs999323 chr17:45371603 T/C cg21624342 chr17:45890973 OSBPL7 0.2 5.44 0.44 2.68e-7 IgG glycosylation; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg20007245 chr22:24372913 LOC391322 -0.7 -6.93 -0.53 2.09e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6495122 0.618 rs4886413 chr15:75262310 G/C cg10253484 chr15:75165896 SCAMP2 -0.6 -5.51 -0.44 2.02e-7 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs244731 1.000 rs244729 chr5:176539018 C/G cg17509989 chr5:176798049 RGS14 0.57 6.74 0.52 5.35e-10 Urate levels in lean individuals; TGCT cis rs6570726 0.791 rs10457788 chr6:145921136 T/A cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9788682 0.655 rs578776 chr15:78888400 G/A cg24631222 chr15:78858424 CHRNA5 0.67 5.38 0.43 3.61e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7552404 0.727 rs6683437 chr1:76316619 G/A cg03433033 chr1:76189801 ACADM 0.6 6.04 0.48 1.66e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10489202 0.608 rs3753934 chr1:168074677 C/T cg24449463 chr1:168025552 DCAF6 -0.53 -5.49 -0.44 2.16e-7 Schizophrenia; TGCT cis rs6882046 0.513 rs2431391 chr5:88046590 C/T cg24804195 chr5:87968844 LOC645323 -0.6 -6.06 -0.48 1.48e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs1775715 0.707 rs2808073 chr10:32179275 A/G cg14930904 chr10:32216787 ARHGAP12 0.51 4.98 0.41 2.04e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs910316 0.874 rs61980828 chr14:75630378 G/A cg23033748 chr14:75592666 NEK9 -0.28 -4.77 -0.39 4.98e-6 Height; TGCT cis rs6089829 0.851 rs6089827 chr20:61668845 C/T cg02380750 chr20:61661411 NA 0.34 5.98 0.47 2.24e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1799949 1.000 rs9646412 chr17:41425893 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs7095607 0.560 rs10997955 chr10:69914664 C/T cg18986048 chr10:69913749 MYPN 0.47 5.14 0.42 1.05e-6 Lung function (FVC); TGCT cis rs12497850 0.931 rs9311430 chr3:48845251 C/T cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs797680 0.753 rs11164881 chr1:93658989 C/A cg17826107 chr1:92977322 EVI5 -0.24 -5.23 -0.43 6.89e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs61931739 0.500 rs7310576 chr12:34474735 T/C cg06521331 chr12:34319734 NA -0.27 -4.53 -0.38 1.37e-5 Morning vs. evening chronotype; TGCT cis rs412000 0.553 rs2680702 chr17:56431549 A/G cg25039879 chr17:56429692 SUPT4H1 0.57 5.45 0.44 2.66e-7 Primary tooth development (time to first tooth eruption); TGCT cis rs11190604 1.000 rs2495758 chr10:102321900 C/G cg23241863 chr10:102295624 HIF1AN 0.66 4.87 0.4 3.37e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7698623 0.541 rs7682273 chr4:88781772 C/T cg27387453 chr4:88533842 DSPP -0.62 -4.64 -0.38 8.66e-6 Cardiovascular disease risk factors; TGCT cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg16423285 chr20:60520624 NA 0.75 9.16 0.64 1.37e-15 Obesity-related traits; TGCT cis rs62244186 0.715 rs10212378 chr3:44667286 C/G cg02073558 chr3:44770973 ZNF501 0.62 6.07 0.48 1.45e-8 Depressive symptoms; TGCT cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.24 0.49 6.41e-9 Schizophrenia; TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg11494091 chr17:61959527 GH2 0.61 14.5 0.79 1.83e-28 Prudent dietary pattern; TGCT trans rs2760061 0.846 rs3094912 chr1:228209815 T/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.08 -0.54 9.5e-11 Diastolic blood pressure; TGCT cis rs6495122 0.630 rs12912343 chr15:75251041 C/G cg09165964 chr15:75287851 SCAMP5 0.52 4.65 0.39 8.45e-6 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs10489202 0.583 rs203782 chr1:167882386 A/G cg24449463 chr1:168025552 DCAF6 0.53 6.17 0.48 8.94e-9 Schizophrenia; TGCT cis rs7819412 0.805 rs2409710 chr8:10979821 A/G cg21775007 chr8:11205619 TDH -0.51 -4.93 -0.4 2.61e-6 Triglycerides; TGCT cis rs9902453 0.780 rs7210991 chr17:28190961 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.62e-11 Coffee consumption (cups per day); TGCT trans rs6089829 0.851 rs10854168 chr20:61669550 A/G cg17470723 chr8:74884337 TCEB1 0.78 6.83 0.52 3.42e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7772486 0.875 rs2814873 chr6:146308932 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.0 0.41 1.91e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg15242686 chr22:24348715 GSTTP1 -0.42 -5.68 -0.45 9.1e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs782590 0.935 rs2627779 chr2:55892356 A/G cg03859395 chr2:55845619 SMEK2 0.89 10.38 0.68 1.49e-18 Metabolic syndrome; TGCT cis rs853679 0.517 rs9357066 chr6:28129831 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7666738 0.830 rs4472144 chr4:98956494 G/A cg18180107 chr4:99064573 C4orf37 0.55 4.98 0.41 2.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7226408 0.749 rs62083174 chr18:34314666 C/A cg06757138 chr18:34340585 FHOD3 0.27 4.79 0.4 4.64e-6 Obesity-related traits; TGCT cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs12049351 0.774 rs10916504 chr1:229655892 A/T cg12130225 chr1:229698885 NA 0.38 4.63 0.38 8.95e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs2153535 0.580 rs2327060 chr6:8447111 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs9486719 1.000 rs2971608 chr6:97039757 T/C cg18709589 chr6:96969512 KIAA0776 -0.78 -6.38 -0.5 3.24e-9 Migraine;Coronary artery disease; TGCT cis rs6977955 0.838 rs917116 chr7:28172739 T/G cg23620719 chr7:28220237 JAZF1 0.62 4.86 0.4 3.46e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6589563 0.609 rs56224630 chr11:116627097 G/A cg01124546 chr11:117515332 DSCAML1 -0.44 -4.77 -0.39 5.18e-6 Eosinophil counts; TGCT cis rs986417 0.748 rs10150234 chr14:61031284 C/G cg27398547 chr14:60952738 C14orf39 -1.35 -10.47 -0.69 8.97e-19 Gut microbiota (bacterial taxa); TGCT cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs9911578 0.813 rs8066773 chr17:56601552 A/G cg05425664 chr17:57184151 TRIM37 -0.66 -6.09 -0.48 1.32e-8 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.595 rs4320356 chr6:26423560 C/T cg15659132 chr6:26577336 NA -0.43 -4.52 -0.38 1.43e-5 Intelligence (multi-trait analysis); TGCT cis rs56804039 0.524 rs4840988 chr8:8403389 C/A cg14215082 chr8:9055850 NA -0.47 -4.7 -0.39 6.74e-6 Cervical cancer; TGCT cis rs2932538 0.922 rs12758377 chr1:113137221 C/A cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs67311347 0.544 rs2123998 chr3:40359005 C/G cg13683864 chr3:40499215 RPL14 0.85 8.54 0.61 3.96e-14 Renal cell carcinoma; TGCT trans rs1814175 0.669 rs11040473 chr11:49703813 C/T cg03929089 chr4:120376271 NA -0.6 -6.95 -0.53 1.88e-10 Height; TGCT cis rs2762353 0.935 rs1165215 chr6:25798932 G/A cg03517284 chr6:25882590 NA -0.52 -5.29 -0.43 5.3e-7 Blood metabolite levels; TGCT cis rs875971 0.658 rs432667 chr7:65514633 A/G cg18876405 chr7:65276391 NA 0.33 4.95 0.41 2.39e-6 Aortic root size; TGCT cis rs10934753 0.560 rs73859048 chr3:125931603 G/A cg01346077 chr3:125931526 NA 0.39 6.1 0.48 1.26e-8 Plasma homocysteine levels (post-methionine load test); TGCT cis rs2795502 1.000 rs2473119 chr10:43339038 A/T cg20628663 chr10:43360327 NA -0.44 -6.37 -0.5 3.4e-9 Blood protein levels; TGCT cis rs992157 0.764 rs4672886 chr2:219185545 C/T cg00012203 chr2:219082015 ARPC2 -0.71 -6.71 -0.52 6.34e-10 Colorectal cancer; TGCT cis rs3027234 0.724 rs11651453 chr17:8103695 A/G cg08322244 chr17:8066669 VAMP2 -0.56 -5.21 -0.42 7.76e-7 Telomere length; TGCT cis rs7959452 0.590 rs11177619 chr12:69758871 G/A cg11871910 chr12:69753446 YEATS4 0.82 8.82 0.62 8.61e-15 Blood protein levels; TGCT cis rs9787249 0.957 rs3738673 chr1:40204823 C/T cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT trans rs208520 1.000 rs208520 chr6:66952828 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.89 -8.42 -0.6 7.99e-14 Exhaled nitric oxide output; TGCT cis rs2562456 0.874 rs2562408 chr19:21709881 C/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs892961 0.932 rs11655686 chr17:75419535 G/A cg05865280 chr17:75406074 SEPT9 0.27 6.31 0.49 4.45e-9 Airflow obstruction; TGCT cis rs9443645 0.775 rs9359359 chr6:79700980 T/C cg09184832 chr6:79620586 NA -0.43 -4.83 -0.4 3.93e-6 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.678 rs10894272 chr11:130731081 A/G cg12179176 chr11:130786555 SNX19 0.77 9.25 0.64 8.44e-16 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2404602 0.692 rs8024476 chr15:76983954 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs42648 0.869 rs42611 chr7:89950060 C/A cg25739043 chr7:89950458 NA -0.73 -7.29 -0.55 3.2e-11 Homocysteine levels; TGCT cis rs3020736 0.500 rs5996111 chr22:42493902 C/T cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.85e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7959452 0.532 rs2291005 chr12:69764388 A/G cg14784868 chr12:69753453 YEATS4 0.83 8.85 0.62 7.59e-15 Blood protein levels; TGCT cis rs9295536 0.651 rs9460707 chr6:22137648 C/G cg25792714 chr6:21666554 FLJ22536 0.51 4.68 0.39 7.53e-6 Neuroblastoma; TGCT cis rs10782582 0.593 rs77208152 chr1:76124255 T/C cg03433033 chr1:76189801 ACADM -0.63 -7.27 -0.55 3.6e-11 Daytime sleep phenotypes; TGCT cis rs6087990 0.735 rs6057647 chr20:31381690 A/T cg13636640 chr20:31349939 DNMT3B 0.95 12.38 0.74 2.06e-23 Ulcerative colitis; TGCT cis rs1322512 1.000 rs1727052 chr6:152947175 T/C cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs6586111 0.967 rs6586110 chr10:82376492 G/A cg03086067 chr10:82368399 SH2D4B -0.23 -4.5 -0.37 1.56e-5 Capecitabine sensitivity; TGCT cis rs10131894 0.575 rs1860935 chr14:75432464 G/A cg08847533 chr14:75593920 NEK9 0.62 5.68 0.45 9.28e-8 Coronary artery disease; TGCT cis rs7091068 0.566 rs7909925 chr10:95507170 A/G cg20715218 chr10:95462985 C10orf4 0.52 4.62 0.38 9.33e-6 Urinary tract infection frequency; TGCT cis rs7119 0.679 rs12909808 chr15:77816944 A/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs3806843 0.576 rs246006 chr5:140339228 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs3733585 0.773 rs13107466 chr4:10019390 G/A cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7647973 0.626 rs11709734 chr3:49745235 G/A cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs6918586 0.658 rs198821 chr6:26123629 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.75 -0.52 4.96e-10 Schizophrenia; TGCT cis rs7312933 0.558 rs7965743 chr12:42736822 A/G cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.18e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs3776081 0.600 rs11167496 chr5:149533956 T/G cg18424208 chr5:149546337 CDX1 -0.25 -4.53 -0.38 1.37e-5 Blood protein levels; TGCT cis rs763121 0.853 rs138706 chr22:39137834 C/G cg06022373 chr22:39101656 GTPBP1 0.72 7.0 0.53 1.39e-10 Menopause (age at onset); TGCT cis rs2204008 0.777 rs6582664 chr12:37947022 A/G cg26384229 chr12:38710491 ALG10B -0.7 -6.12 -0.48 1.11e-8 Bladder cancer; TGCT cis rs727505 1.000 rs56321835 chr7:124529622 T/C cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs2204008 0.715 rs11514282 chr12:38169056 G/T cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT cis rs595982 0.527 rs73061656 chr19:49372355 G/A cg17863274 chr19:49399704 TULP2 -0.47 -6.81 -0.52 3.78e-10 Red cell distribution width; TGCT cis rs13108904 0.875 rs1732099 chr4:1282696 T/C cg08683831 chr4:1404607 NA -0.46 -4.43 -0.37 2.01e-5 Obesity-related traits; TGCT cis rs60843830 0.928 rs55742348 chr2:217563 T/A cg00108164 chr2:264199 ACP1;SH3YL1 0.73 6.56 0.51 1.29e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs12497850 1.000 rs12493578 chr3:48730116 C/T cg18654377 chr3:49208889 KLHDC8B 0.44 5.88 0.47 3.56e-8 Parkinson's disease; TGCT cis rs9911578 0.967 rs8082544 chr17:57185807 C/T cg05425664 chr17:57184151 TRIM37 0.68 6.9 0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs903263 0.932 rs1021490 chr1:84574282 C/T cg09664975 chr1:84543551 PRKACB 0.49 4.55 0.38 1.25e-5 Breast cancer (male); TGCT cis rs11250097 0.528 rs36043848 chr8:11309533 A/G cg21775007 chr8:11205619 TDH -0.52 -4.68 -0.39 7.53e-6 Neuroticism; TGCT cis rs12220898 0.749 rs6537519 chr10:50479824 G/T cg06072769 chr10:50146962 WDFY4 -0.32 -4.51 -0.38 1.48e-5 Inflammatory biomarkers; TGCT cis rs13188771 0.651 rs12520498 chr5:100881358 G/A cg10455971 chr5:101119566 NA 0.44 4.46 0.37 1.83e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs4930561 0.714 rs7945995 chr11:67938302 A/G cg04465784 chr11:67976953 SUV420H1 -0.38 -5.47 -0.44 2.37e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs72781680 0.898 rs55841168 chr2:24007926 T/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs3902035 0.964 rs118167130 chr6:119009065 G/C cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs9326248 0.817 rs1242127 chr11:117076564 A/G cg16524733 chr11:117070046 TAGLN -0.32 -4.74 -0.39 5.84e-6 Blood protein levels; TGCT cis rs12477438 0.765 rs72957180 chr2:99694452 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs7954584 0.616 rs10743186 chr12:122356436 C/T cg21171335 chr12:122356390 WDR66 0.59 6.19 0.49 8.15e-9 Mean corpuscular volume; TGCT cis rs2839186 0.903 rs61182475 chr21:47707050 T/A cg13732083 chr21:47605072 C21orf56 0.34 4.55 0.38 1.27e-5 Testicular germ cell tumor; TGCT cis rs7178572 0.568 rs10152181 chr15:77678346 A/G cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs73058052 0.597 rs10406941 chr19:50091464 A/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.66 5.23 0.43 6.91e-7 Fibrinogen levels; TGCT cis rs6977955 1.000 rs6977955 chr7:28156887 A/G cg23620719 chr7:28220237 JAZF1 -0.67 -5.1 -0.42 1.26e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg10819733 chr22:24237672 NA -0.3 -5.09 -0.42 1.29e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9527 0.569 rs10786730 chr10:104724200 G/A cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT trans rs9650657 0.535 rs7011756 chr8:11019578 C/G cg15556689 chr8:8085844 FLJ10661 -0.86 -8.58 -0.61 3.26e-14 Neuroticism; TGCT cis rs4988958 0.565 rs12712146 chr2:103008714 C/T cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma (childhood onset); TGCT cis rs1018836 0.847 rs2285231 chr8:91545387 G/T cg16814680 chr8:91681699 NA -0.86 -9.52 -0.65 1.82e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs60154123 0.505 rs76426571 chr1:210041634 C/T cg21951975 chr1:209979733 IRF6 0.69 5.18 0.42 8.74e-7 Coronary artery disease; TGCT cis rs60154123 0.505 rs77990373 chr1:210041111 T/C cg21951975 chr1:209979733 IRF6 0.69 5.18 0.42 8.74e-7 Coronary artery disease; TGCT cis rs6090919 0.501 rs17366795 chr20:47481831 C/T cg12392473 chr20:48099331 KCNB1 -0.47 -4.52 -0.38 1.4e-5 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.554 rs3846169 chr3:9997054 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.32 4.94 0.41 2.51e-6 Alzheimer's disease; TGCT cis rs10744422 1.000 rs2292134 chr12:123334033 C/G cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs60154123 0.505 rs2206043 chr1:210042983 G/A cg04352962 chr1:209979756 IRF6 0.69 4.73 0.39 6.04e-6 Coronary artery disease; TGCT cis rs7917772 0.503 rs7093285 chr10:104374815 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.78 7.97 0.58 9.02e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10716631 1 rs10716631 chr2:219138170 T/G cg00012203 chr2:219082015 ARPC2 0.77 7.98 0.58 8.28e-13 High light scatter reticulocyte percentage of red cells;Plateletcrit; TGCT cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg13695892 chr22:41940480 POLR3H 0.87 8.24 0.59 2.06e-13 Vitiligo; TGCT cis rs56176327 0.532 rs9849038 chr3:49771990 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Intelligence (multi-trait analysis); TGCT cis rs288326 0.561 rs75848966 chr2:183878093 A/C cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs782590 0.837 rs782584 chr2:55921116 C/G cg03859395 chr2:55845619 SMEK2 -0.85 -10.02 -0.67 1.13e-17 Metabolic syndrome; TGCT cis rs7412746 0.552 rs4970980 chr1:150864992 A/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs7666738 0.830 rs9994346 chr4:99037986 A/G cg17366294 chr4:99064904 C4orf37 0.73 6.93 0.53 2.07e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1729951 0.575 rs12494558 chr3:136678781 C/G cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs7937682 0.921 rs11213940 chr11:111433927 C/A cg09085632 chr11:111637200 PPP2R1B 0.87 7.31 0.55 2.9e-11 Primary sclerosing cholangitis; TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg07167872 chr1:205819463 PM20D1 0.59 7.56 0.56 7.74e-12 Menarche (age at onset); TGCT cis rs2046867 0.818 rs62249863 chr3:72868666 G/C cg25664220 chr3:72788482 NA -0.56 -7.04 -0.53 1.16e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9902453 0.967 rs4493117 chr17:28489770 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs9990333 0.562 rs58079878 chr3:195827491 T/C cg14488913 chr3:195402182 SDHAP2 -0.35 -4.44 -0.37 1.95e-5 Iron status biomarkers (transferrin levels);Iron status biomarkers (transferrin saturation); TGCT cis rs941408 0.928 rs2260414 chr19:2796316 G/A cg06609049 chr19:2785107 THOP1 0.83 8.08 0.59 4.82e-13 Total cholesterol levels; TGCT cis rs28595532 0.920 rs55726697 chr4:119742863 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2486288 0.656 rs2413773 chr15:45549442 C/A cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs2797160 1.000 rs2797154 chr6:126005197 A/G cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs950169 0.544 rs62021193 chr15:85170583 C/G cg12863693 chr15:85201151 NMB 0.44 5.24 0.43 6.63e-7 Schizophrenia; TGCT cis rs4919694 1.000 rs12242000 chr10:104702413 A/C cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs4824093 0.610 rs12106611 chr22:50242686 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.06 -6.46 -0.5 2.18e-9 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.52 4.56 0.38 1.21e-5 Prudent dietary pattern; TGCT cis rs2677744 0.719 rs1266492 chr15:91456102 T/C cg01710897 chr15:91497902 RCCD1 0.34 4.68 0.39 7.35e-6 Attention deficit hyperactivity disorder; TGCT cis rs425277 1.000 rs427811 chr1:2075560 T/G cg03732007 chr1:2071316 PRKCZ 0.25 5.0 0.41 1.93e-6 Height; TGCT cis rs6089584 0.888 rs6061983 chr20:60621202 T/C cg06108461 chr20:60628389 TAF4 -0.69 -10.64 -0.69 3.59e-19 Body mass index; TGCT cis rs651907 0.557 rs35117343 chr3:101445126 A/G cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.78 -0.52 4.35e-10 Colorectal cancer; TGCT cis rs4927850 0.957 rs4927851 chr3:195751853 A/G cg12923728 chr3:195709715 SDHAP1 -0.36 -7.57 -0.56 7.39e-12 Pancreatic cancer; TGCT cis rs11696845 0.649 rs6031782 chr20:43383832 A/G cg25301532 chr20:43378953 KCNK15 -0.46 -4.98 -0.41 2.09e-6 Obesity-related traits; TGCT cis rs9372498 0.536 rs9489442 chr6:118885950 A/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.83 -0.4 4.03e-6 Diastolic blood pressure; TGCT cis rs17152411 1.000 rs17152433 chr10:126670356 G/A cg07906193 chr10:126599966 NA 0.39 4.79 0.4 4.66e-6 Height; TGCT cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 0.93 7.77 0.57 2.59e-12 Platelet count; TGCT trans rs77457752 0.525 rs7874947 chr9:13899539 A/C cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.04e-10 Breast cancer; TGCT cis rs208520 0.837 rs208486 chr6:66926255 A/T cg07460842 chr6:66804631 NA -0.94 -9.3 -0.64 6.32e-16 Exhaled nitric oxide output; TGCT cis rs6430585 0.583 rs4594504 chr2:136625113 A/C cg07169764 chr2:136633963 MCM6 1.24 12.25 0.74 4.19e-23 Corneal structure; TGCT cis rs873946 0.586 rs12259688 chr10:134549628 A/G cg18305652 chr10:134549665 INPP5A 0.34 5.39 0.44 3.46e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs875971 0.660 rs12698534 chr7:65986845 C/T cg18876405 chr7:65276391 NA 0.36 5.41 0.44 3.12e-7 Aortic root size; TGCT cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs4642101 0.611 rs6442331 chr3:12820636 T/G cg05775895 chr3:12838266 CAND2 0.68 7.27 0.55 3.54e-11 QRS complex (12-leadsum); TGCT cis rs1008375 0.898 rs7670500 chr4:17586957 A/G cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs57920188 0.640 rs4378174 chr1:4080885 C/T cg20703997 chr1:4087676 NA 0.44 5.45 0.44 2.64e-7 Interleukin-17 levels; TGCT cis rs8072100 1.000 rs11870935 chr17:45732605 G/A cg08085267 chr17:45401833 C17orf57 0.47 5.12 0.42 1.14e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg23850913 chr6:15505452 JARID2 0.96 5.75 0.46 6.42e-8 Gambling; TGCT cis rs10197940 0.578 rs1061305 chr2:152346979 T/C cg06191203 chr2:152266755 RIF1 -0.61 -5.14 -0.42 1.03e-6 Lung cancer; TGCT cis rs7618915 0.571 rs1961958 chr3:52585990 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.86 0.47 3.95e-8 Bipolar disorder; TGCT cis rs13256369 0.951 rs13259955 chr8:8565885 C/G cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs7572733 0.534 rs1607374 chr2:198800440 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.18 0.42 8.86e-7 Dermatomyositis; TGCT cis rs35306767 0.715 rs12772979 chr10:1034412 C/T cg18964960 chr10:1102726 WDR37 0.78 5.45 0.44 2.58e-7 Eosinophil percentage of granulocytes; TGCT cis rs6964587 1.000 rs10235941 chr7:91587050 T/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT trans rs57221529 0.766 rs72703042 chr5:579269 C/T cg25482853 chr8:67687455 SGK3 1.16 10.5 0.69 7.91e-19 Lung disease severity in cystic fibrosis; TGCT cis rs75059851 0.756 rs7106715 chr11:133838905 A/G cg14047540 chr11:133829660 NA 0.52 5.11 0.42 1.18e-6 Schizophrenia; TGCT cis rs28595532 0.920 rs115472708 chr4:119773407 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg01411255 chr17:61851458 DDX42;CCDC47 1.12 15.17 0.81 4.81e-30 Height; TGCT cis rs735396 0.595 rs1169279 chr12:121455873 C/T cg02403541 chr12:121454288 C12orf43 0.87 9.52 0.65 1.88e-16 N-glycan levels; TGCT cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg09436375 chr6:42928200 GNMT -0.42 -5.41 -0.44 3.16e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs79349575 0.783 rs318096 chr17:46975370 G/A cg07967210 chr17:47022446 SNF8 0.43 6.08 0.48 1.4e-8 Type 2 diabetes; TGCT cis rs968567 0.559 rs174548 chr11:61571348 C/G cg19610905 chr11:61596333 FADS2 -1.07 -11.76 -0.73 6.62e-22 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs7582180 0.652 rs11678158 chr2:100932297 T/C cg14675211 chr2:100938903 LONRF2 0.53 5.11 0.42 1.16e-6 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs986417 0.901 rs1955688 chr14:60989237 G/A cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.33 -0.55 2.59e-11 Prostate cancer; TGCT cis rs7917772 0.582 rs10883753 chr10:104372441 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3858526 1.000 rs3858527 chr11:5959848 G/A cg05234568 chr11:5960015 NA -0.44 -4.49 -0.37 1.61e-5 DNA methylation (variation); TGCT cis rs7772486 0.875 rs2474353 chr6:146323883 G/A cg05347473 chr6:146136440 FBXO30 0.55 5.27 0.43 5.75e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.688 rs113940455 chr3:10014165 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.71 -0.52 6.05e-10 Alzheimer's disease; TGCT cis rs3741151 1.000 rs74795285 chr11:73033387 A/G cg17517138 chr11:73019481 ARHGEF17 1.04 5.14 0.42 1.05e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs1218582 0.772 rs4845689 chr1:154885524 A/G cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs2301573 0.607 rs9837325 chr3:129315831 C/A cg07730360 chr3:128845626 NA 0.28 5.52 0.44 1.94e-7 Hip circumference; TGCT cis rs1218582 0.741 rs10908444 chr1:154840287 G/A cg06221963 chr1:154839813 KCNN3 -0.73 -12.61 -0.75 5.86e-24 Prostate cancer; TGCT cis rs2549003 1.000 rs2070724 chr5:131822072 A/G cg02551604 chr5:131831745 NA -0.9 -12.1 -0.74 9.75e-23 Asthma (sex interaction); TGCT cis rs11098499 0.564 rs11098507 chr4:120288286 G/A cg09307838 chr4:120376055 NA 0.58 5.7 0.46 8.42e-8 Corneal astigmatism; TGCT cis rs1577917 0.655 rs7742691 chr6:86278691 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 4.76 0.39 5.23e-6 Response to antipsychotic treatment; TGCT trans rs7819412 0.511 rs7464263 chr8:11434176 A/T cg06636001 chr8:8085503 FLJ10661 -0.79 -7.27 -0.55 3.49e-11 Triglycerides; TGCT cis rs6918586 0.557 rs198827 chr6:26121002 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.75 -0.52 4.96e-10 Schizophrenia; TGCT cis rs909674 0.818 rs5750830 chr22:39840828 C/A cg02038168 chr22:39784481 NA -0.74 -5.76 -0.46 6.36e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6088580 0.634 rs6088488 chr20:32992631 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs4862307 0.836 rs11132220 chr4:184997247 A/T cg06737308 chr4:185021514 ENPP6 -0.34 -4.99 -0.41 1.96e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs9291683 0.588 rs3756236 chr4:10013463 T/A cg11266682 chr4:10021025 SLC2A9 0.73 11.04 0.7 3.63e-20 Bone mineral density; TGCT cis rs6570726 0.791 rs6570693 chr6:145910841 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.28 0.64 7.13e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs12048904 0.505 rs6577209 chr1:101255080 A/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.76 6.71 0.52 6.06e-10 Multiple sclerosis; TGCT cis rs3764628 1.000 rs11668413 chr19:18782027 G/A cg20098710 chr19:19640075 YJEFN3 -0.46 -5.22 -0.42 7.26e-7 Orofacial clefts; TGCT cis rs644799 0.672 rs61902245 chr11:95517737 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.8 9.01 0.63 3.14e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9467711 1.000 rs9467708 chr6:26327956 T/C cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2235642 0.859 rs12599207 chr16:1606445 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.29 -5.08 -0.42 1.35e-6 Coronary artery disease; TGCT cis rs9443645 0.810 rs7753531 chr6:79789996 A/C cg09184832 chr6:79620586 NA -0.45 -4.87 -0.4 3.28e-6 Intelligence (multi-trait analysis); TGCT cis rs492146 0.819 rs584124 chr6:52838196 G/A cg06706454 chr6:52930286 FBXO9 -0.5 -4.63 -0.38 9.12e-6 Epilepsy (remission after treatment); TGCT cis rs763121 0.853 rs2072795 chr22:39064209 A/G cg06022373 chr22:39101656 GTPBP1 -0.78 -7.56 -0.56 7.78e-12 Menopause (age at onset); TGCT cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4788815 0.718 rs6499545 chr16:71889173 C/T cg06353428 chr16:71660113 MARVELD3 0.83 7.37 0.55 2.07e-11 Metabolite levels; TGCT cis rs2354432 0.607 rs6694347 chr1:146751140 T/C cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs10197940 0.789 rs2444256 chr2:152280365 C/T cg19508488 chr2:152266495 RIF1 0.72 6.62 0.51 9.56e-10 Lung cancer; TGCT cis rs12681287 0.711 rs28506490 chr8:87246118 T/C cg27223183 chr8:87520930 FAM82B -0.81 -5.77 -0.46 5.91e-8 Caudate activity during reward; TGCT cis rs4319547 0.585 rs7952868 chr12:122846949 A/G cg05707623 chr12:122985044 ZCCHC8 -0.63 -4.88 -0.4 3.18e-6 Body mass index; TGCT cis rs4074961 0.565 rs10908362 chr1:38061706 G/C cg11397548 chr1:38022522 DNALI1 0.42 4.81 0.4 4.38e-6 Axial length; TGCT cis rs10838634 0.706 rs11039012 chr11:46883318 A/C cg18332754 chr11:46939436 LRP4 -0.89 -4.77 -0.39 5.13e-6 Schizophrenia; TGCT cis rs6882046 0.513 rs254779 chr5:88019629 T/C cg22951263 chr5:87985283 NA -0.58 -6.18 -0.49 8.49e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT trans rs5771242 0.776 rs6010198 chr22:50610628 A/G cg26607758 chr8:91997553 NA -0.79 -9.26 -0.64 7.59e-16 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs2230307 0.572 rs2810419 chr1:100643968 C/A cg24955406 chr1:100503596 HIAT1 -0.73 -4.94 -0.41 2.5e-6 Carotid intima media thickness; TGCT cis rs1799949 0.929 rs12937015 chr17:41307473 A/C cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs61935443 0.666 rs11107781 chr12:95301086 T/A cg21533806 chr12:95267307 NA 0.58 4.85 0.4 3.7e-6 Schizophrenia; TGCT cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6840360 0.571 rs17360385 chr4:152587970 C/A cg17479576 chr4:152424074 FAM160A1 -0.74 -8.24 -0.59 2.06e-13 Intelligence (multi-trait analysis); TGCT cis rs2933343 0.679 rs789221 chr3:128591625 A/G cg11901034 chr3:128598214 ACAD9 -0.62 -6.01 -0.48 1.88e-8 IgG glycosylation; TGCT cis rs875971 0.928 rs6970357 chr7:65968878 T/C cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs12477438 0.677 rs12475034 chr2:99699464 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.67 -5.22 -0.42 7.16e-7 Chronic sinus infection; TGCT cis rs1008375 0.932 rs6449321 chr4:17644472 A/G cg16339924 chr4:17578868 LAP3 0.67 5.48 0.44 2.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6089584 0.853 rs1740367 chr20:60574834 C/T cg16423285 chr20:60520624 NA -0.61 -6.64 -0.51 8.67e-10 Body mass index; TGCT cis rs1395 0.778 rs724311 chr2:27441645 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.47 0.65 2.4e-16 Blood metabolite levels; TGCT cis rs9929218 0.529 rs35854485 chr16:68730855 C/G cg01251360 chr16:68772225 CDH1 -0.25 -4.57 -0.38 1.15e-5 Colorectal cancer; TGCT cis rs739401 0.595 rs6578304 chr11:2998279 A/G cg05729581 chr11:3078854 CARS 0.54 4.81 0.4 4.21e-6 Longevity; TGCT cis rs8103278 1.000 rs36091860 chr19:46312880 G/A cg14061069 chr19:46274453 DMPK -0.42 -5.86 -0.47 3.86e-8 Coronary artery disease; TGCT cis rs589448 0.902 rs315138 chr12:69764850 A/T cg11871910 chr12:69753446 YEATS4 0.88 10.41 0.68 1.28e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs2549003 1.000 rs3846732 chr5:131816087 T/C cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs7944584 0.655 rs11039183 chr11:47346940 G/A cg20307385 chr11:47447363 PSMC3 0.8 7.85 0.58 1.7e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs6901250 0.632 rs339355 chr6:117196503 A/T cg12892004 chr6:117198278 RFX6 -0.44 -5.48 -0.44 2.3e-7 C-reactive protein levels; TGCT cis rs4319547 0.915 rs10773208 chr12:122970156 T/C cg23029597 chr12:123009494 RSRC2 -0.29 -4.87 -0.4 3.34e-6 Body mass index; TGCT cis rs6582630 0.502 rs4379906 chr12:38295673 G/A cg26384229 chr12:38710491 ALG10B 0.77 6.88 0.53 2.6200000000000003e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs644799 1.000 rs514170 chr11:95556696 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs921968 0.541 rs72965126 chr2:219330189 C/T cg02176678 chr2:219576539 TTLL4 -0.47 -6.78 -0.52 4.34e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2997447 0.846 rs12069719 chr1:26411918 A/G cg03844060 chr1:26490628 NA 0.27 4.52 0.38 1.41e-5 QRS complex (12-leadsum); TGCT cis rs6582630 0.519 rs11495376 chr12:38284957 A/C cg26384229 chr12:38710491 ALG10B 0.82 7.18 0.54 5.6e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs12540874 0.931 rs4245555 chr7:50661409 A/G cg18232548 chr7:50535776 DDC -0.29 -4.89 -0.4 3.01e-6 Systemic sclerosis; TGCT cis rs9902453 1.000 rs4581755 chr17:28427898 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.57 0.51 1.22e-9 Coffee consumption (cups per day); TGCT cis rs6459788 0.657 rs887627 chr7:157237391 G/A cg06271696 chr7:157225062 NA -0.29 -5.13 -0.42 1.07e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs17767294 0.708 rs72848775 chr6:27949830 A/G cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs826838 0.967 rs11169142 chr12:39085773 A/T cg13010199 chr12:38710504 ALG10B -0.59 -4.89 -0.4 3e-6 Heart rate; TGCT cis rs10875746 0.855 rs73102067 chr12:48494426 A/C cg20731937 chr12:48336164 NA 0.63 4.96 0.41 2.24e-6 Longevity (90 years and older); TGCT cis rs12477438 0.715 rs6724476 chr2:99627316 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs801193 0.660 rs974239 chr7:66213491 G/A cg18876405 chr7:65276391 NA 0.33 4.89 0.4 3.12e-6 Aortic root size; TGCT cis rs1372520 1.000 rs1372520 chr4:90757505 T/C cg15133208 chr4:90757351 SNCA -0.5 -5.77 -0.46 5.88e-8 Neuroticism; TGCT cis rs7219014 1 rs7219014 chr17:37624790 A/G cg15445000 chr17:37608096 MED1 0.33 4.93 0.4 2.59e-6 Urinary metabolites; TGCT cis rs992157 0.764 rs4552182 chr2:219184872 G/T cg00012203 chr2:219082015 ARPC2 0.7 6.58 0.51 1.16e-9 Colorectal cancer; TGCT cis rs42648 0.935 rs42635 chr7:89966198 T/A cg25739043 chr7:89950458 NA -0.76 -7.64 -0.57 5.2e-12 Homocysteine levels; TGCT cis rs11098499 0.909 rs11723839 chr4:120299673 G/A cg09307838 chr4:120376055 NA 0.62 5.94 0.47 2.66e-8 Corneal astigmatism; TGCT cis rs17401966 0.838 rs12139981 chr1:10390696 T/C cg19773385 chr1:10388646 KIF1B -0.23 -5.45 -0.44 2.63e-7 Hepatocellular carcinoma; TGCT cis rs1372520 0.684 rs2583963 chr4:90727088 C/T cg01966878 chr4:90757139 SNCA -0.31 -4.84 -0.4 3.8e-6 Neuroticism; TGCT trans rs28735056 0.967 rs56071379 chr18:77647406 G/A cg05926928 chr17:57297772 GDPD1 -0.68 -7.21 -0.54 4.89e-11 Schizophrenia; TGCT cis rs7777484 0.500 rs2533885 chr7:2835655 C/T cg11411865 chr7:2701802 TTYH3 0.19 4.51 0.38 1.47e-5 Height; TGCT cis rs12548874 0.618 rs10100651 chr8:95887225 G/C cg09323728 chr8:95962352 TP53INP1 -0.42 -4.73 -0.39 6.03e-6 Hemoglobin concentration; TGCT cis rs6933660 0.800 rs6930557 chr6:151755806 G/A cg17179660 chr6:151773299 C6orf211;RMND1 -0.54 -4.92 -0.4 2.64e-6 Menarche (age at onset); TGCT cis rs2929278 0.561 rs3099045 chr15:43923955 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.45 4.5 0.37 1.54e-5 Schizophrenia; TGCT cis rs3916 0.911 rs3999408 chr12:121167387 C/T cg21892295 chr12:121157589 UNC119B -0.23 -4.5 -0.37 1.55e-5 Urinary metabolites (H-NMR features); TGCT cis rs6964587 1.000 rs7806157 chr7:91601930 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs7246657 0.722 rs1564208 chr19:38041221 A/G cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs854765 0.583 rs7207043 chr17:17819188 A/G cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.83e-6 Total body bone mineral density; TGCT cis rs35306767 0.715 rs17293580 chr10:1034895 T/C cg26597838 chr10:835615 NA 0.64 7.08 0.54 9.37e-11 Eosinophil percentage of granulocytes; TGCT cis rs3784262 0.904 rs12901462 chr15:58316487 A/G cg12031962 chr15:58353849 ALDH1A2 -0.52 -7.93 -0.58 1.1e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs8072100 0.713 rs4968257 chr17:45430534 A/G cg08085267 chr17:45401833 C17orf57 -0.5 -5.63 -0.45 1.14e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7666738 0.830 rs17027198 chr4:98991085 G/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs644799 0.511 rs10831420 chr11:95478209 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.65 6.26 0.49 5.81e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9381040 0.701 rs4711658 chr6:41162891 C/T cg03526776 chr6:41159608 TREML2 -0.28 -6.15 -0.48 9.78e-9 Alzheimer's disease (late onset); TGCT cis rs736408 0.648 rs3774355 chr3:52817778 G/A cg10802521 chr3:52805072 NEK4 -0.71 -8.43 -0.6 7.23e-14 Bipolar disorder; TGCT cis rs4653767 1.000 rs708774 chr1:226921530 C/G cg10327440 chr1:227177885 CDC42BPA -0.47 -5.24 -0.43 6.64e-7 Parkinson's disease; TGCT cis rs2153535 0.541 rs6905934 chr6:8440043 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT trans rs28735056 0.875 rs62103181 chr18:77625652 A/G cg05926928 chr17:57297772 GDPD1 0.65 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs7959452 0.527 rs4761157 chr12:69780907 A/G cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg03351412 chr1:154909251 PMVK 0.52 4.92 0.4 2.66e-6 Prostate cancer; TGCT cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12200560 0.505 rs211183 chr6:97074723 G/T cg06623918 chr6:96969491 KIAA0776 -0.56 -4.56 -0.38 1.19e-5 Coronary heart disease; TGCT cis rs2933343 1.000 rs1683776 chr3:128622760 G/T cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs4242434 0.927 rs7843616 chr8:22466541 T/C cg21658235 chr8:22456391 C8orf58 0.43 4.53 0.38 1.37e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs514406 0.505 rs436363 chr1:53172163 T/C cg24675658 chr1:53192096 ZYG11B -0.77 -8.85 -0.62 7.57e-15 Monocyte count; TGCT cis rs854572 0.600 rs854570 chr7:94952692 C/A cg17330251 chr7:94953956 PON1 0.51 6.68 0.51 7.16e-10 Paraoxonase activity; TGCT cis rs12210905 1.000 rs41269245 chr6:27100096 G/A cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs10510102 0.872 rs12259144 chr10:123724948 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs11122272 0.766 rs1435166 chr1:231502310 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -6.92 -0.53 2.19e-10 Hemoglobin concentration; TGCT trans rs1814175 0.817 rs7950856 chr11:49976394 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs1865760 1.000 rs56118523 chr6:25908975 A/G cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs7731657 0.537 rs3962196 chr5:130372512 A/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs12615966 0.932 rs60065121 chr2:105368305 T/C cg16465502 chr2:105461796 NA 0.75 4.65 0.39 8.22e-6 Pancreatic cancer; TGCT cis rs11105298 0.891 rs10858902 chr12:89927789 A/G cg00757033 chr12:89920650 WDR51B 0.3 4.65 0.39 8.21e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg03517284 chr6:25882590 NA 0.89 9.16 0.64 1.32e-15 Blood metabolite levels; TGCT cis rs7618915 0.524 rs10433615 chr3:52638482 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs78456975 1.000 rs13397299 chr2:1564222 A/C cg01028140 chr2:1542097 TPO -0.33 -4.54 -0.38 1.29e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2228479 0.717 rs34027607 chr16:89808939 T/C cg27121462 chr16:89883253 FANCA 0.77 4.61 0.38 9.93e-6 Skin colour saturation; TGCT cis rs5769765 0.773 rs7410291 chr22:50300078 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.21 0.42 7.51e-7 Schizophrenia; TGCT cis rs12478296 0.786 rs72620862 chr2:243044787 T/C cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs7843479 0.898 rs4311656 chr8:21802276 T/G cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs6940638 0.513 rs4424065 chr6:27036456 C/T cg05738196 chr6:26577821 NA -0.54 -5.21 -0.42 7.68e-7 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs72703080 chr5:595238 A/G cg09021430 chr5:549028 NA -0.43 -5.83 -0.46 4.57e-8 Obesity-related traits; TGCT cis rs6460942 1.000 rs7808819 chr7:12297440 C/T cg06484146 chr7:12443880 VWDE -0.54 -4.81 -0.4 4.33e-6 Coronary artery disease; TGCT cis rs2282802 0.660 rs4463213 chr5:139545748 G/A cg01081189 chr5:139537190 NA -0.3 -5.37 -0.43 3.82e-7 Intelligence (multi-trait analysis); TGCT cis rs11958404 0.789 rs72818150 chr5:157484121 A/G cg05962755 chr5:157440814 NA 0.35 4.56 0.38 1.23e-5 IgG glycosylation; TGCT cis rs9929218 0.906 rs10852450 chr16:68749529 G/A cg01251360 chr16:68772225 CDH1 0.3 4.94 0.41 2.45e-6 Colorectal cancer; TGCT cis rs1348850 0.872 rs7559521 chr2:178452328 A/G cg22681709 chr2:178499509 PDE11A 0.41 5.18 0.42 8.85e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1580019 0.961 rs766657 chr7:32499510 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.7 0.57 3.71e-12 Cognitive ability; TGCT cis rs1577917 1.000 rs12199516 chr6:86726221 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs4468007 0.505 rs4836865 chr9:124620721 G/A cg01549227 chr9:124980074 LHX6 -0.3 -4.55 -0.38 1.24e-5 Educational attainment; TGCT cis rs4975709 0.589 rs4975744 chr5:1860049 A/G cg15595755 chr5:1867978 NA 0.46 4.88 0.4 3.26e-6 Cardiovascular disease risk factors; TGCT cis rs7647973 0.588 rs4855848 chr3:49653457 C/T cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs9467711 0.606 rs9393706 chr6:26361500 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4654899 0.772 rs12404954 chr1:21074727 A/G cg01072550 chr1:21505969 NA -0.48 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg06238570 chr21:40685208 BRWD1 -0.84 -9.31 -0.64 6.01e-16 Cognitive function; TGCT cis rs7843479 0.965 rs878872 chr8:21834567 A/G cg17168535 chr8:21777572 XPO7 0.63 5.8 0.46 5.08e-8 Mean corpuscular volume; TGCT cis rs7822232 1.000 rs6558296 chr8:145143802 G/A cg26272248 chr8:145163034 KIAA1875 -0.49 -4.81 -0.4 4.24e-6 Blood metabolite levels; TGCT cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.57 5.32 0.43 4.62e-7 Colorectal cancer; TGCT cis rs9916302 0.752 rs8071300 chr17:37508524 G/C cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg11301795 chr4:187892539 NA -0.33 -4.82 -0.4 4.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg19723775 chr5:179050963 HNRNPH1 0.47 4.52 0.38 1.42e-5 Lung cancer; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.11e-7 Lymphocyte counts; TGCT cis rs7552404 0.924 rs7550974 chr1:76204185 A/G cg10523679 chr1:76189770 ACADM 0.89 9.88 0.66 2.42e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9611565 0.649 rs5758434 chr22:42116163 G/A cg06634786 chr22:41940651 POLR3H 0.82 7.9 0.58 1.3e-12 Vitiligo; TGCT cis rs858239 0.829 rs2268744 chr7:23332280 C/T cg05602783 chr7:23145260 KLHL7 -0.72 -5.71 -0.46 7.84e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs5750830 0.597 rs4821889 chr22:39777254 T/C cg01416388 chr22:39784598 NA -0.63 -6.66 -0.51 8.09e-10 Intelligence (multi-trait analysis); TGCT cis rs12478296 0.685 rs12473450 chr2:242991746 C/T cg06360820 chr2:242988706 NA -0.65 -5.18 -0.42 8.6e-7 Obesity-related traits; TGCT cis rs4886920 0.601 rs4589520 chr15:78079434 C/G cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs9902453 0.542 rs3809789 chr17:27955761 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 7.59 0.56 6.48e-12 Coffee consumption (cups per day); TGCT cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg02503808 chr4:7069936 GRPEL1 1.06 10.42 0.68 1.18e-18 Monocyte percentage of white cells; TGCT cis rs514406 0.683 rs6588440 chr1:53209587 C/T cg01802117 chr1:53393560 SCP2 0.44 5.14 0.42 1.04e-6 Monocyte count; TGCT cis rs7523273 0.606 rs10449303 chr1:207961058 A/G cg22525895 chr1:207977042 MIR29B2 -0.52 -8.74 -0.62 1.38e-14 Schizophrenia; TGCT cis rs1862618 0.802 rs2591949 chr5:56132627 T/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs10791323 0.569 rs5019134 chr11:133713082 G/C cg15485101 chr11:133734466 NA 0.39 5.18 0.42 8.85e-7 Childhood ear infection; TGCT cis rs6912958 0.781 rs2300906 chr6:88207155 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs7095607 0.742 rs7914243 chr10:69928679 A/G cg18986048 chr10:69913749 MYPN 0.46 5.2 0.42 7.88e-7 Lung function (FVC); TGCT cis rs9486719 0.947 rs11757102 chr6:96885073 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs9467711 0.651 rs17528178 chr6:25983777 C/T cg16898833 chr6:26189333 HIST1H4D 1.36 6.0 0.47 2.05e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs6845621 0.901 rs1452553 chr4:18920030 C/G cg12196642 chr4:18937545 NA -0.24 -4.45 -0.37 1.89e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs611744 0.647 rs4735053 chr8:109260776 A/G cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.42e-11 Dupuytren's disease; TGCT cis rs6061231 0.624 rs8668 chr20:60964064 C/T cg22541963 chr20:60982533 CABLES2 -0.58 -4.5 -0.37 1.52e-5 Colorectal cancer; TGCT cis rs9952991 0.941 rs888270 chr18:12774894 G/A cg23544223 chr18:12777786 NA -0.63 -5.78 -0.46 5.6e-8 Inflammatory skin disease; TGCT cis rs11190604 1.000 rs10509744 chr10:102271579 C/T cg23241863 chr10:102295624 HIF1AN 0.68 5.18 0.42 8.56e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7772486 0.869 rs2777473 chr6:146301494 G/A cg23711669 chr6:146136114 FBXO30 0.77 7.93 0.58 1.08e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs11585357 0.947 rs2977304 chr1:17611615 T/C cg08277548 chr1:17600880 PADI3 0.97 9.95 0.67 1.7e-17 Hair shape; TGCT cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs4319547 0.774 rs10773394 chr12:123124778 C/A cg23029597 chr12:123009494 RSRC2 -0.26 -4.51 -0.38 1.51e-5 Body mass index; TGCT cis rs4970988 0.787 rs1532770 chr1:150725335 G/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.94 0.41 2.46e-6 Urate levels; TGCT cis rs66569888 0.507 rs67196165 chr2:106886496 C/G cg16099169 chr2:106886729 NA -0.48 -6.16 -0.48 9.37e-9 Facial morphology (factor 23); TGCT cis rs5750830 0.645 rs756640 chr22:39779300 G/A cg24399712 chr22:39784796 NA -1.04 -13.34 -0.77 1e-25 Intelligence (multi-trait analysis); TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg02675527 chr2:114030824 PAX8;LOC440839 -0.52 -6.86 -0.52 2.9e-10 Lymphocyte counts; TGCT cis rs854765 1.000 rs854765 chr17:18012730 T/C cg04398451 chr17:18023971 MYO15A 0.31 4.84 0.4 3.83e-6 Total body bone mineral density; TGCT cis rs2404602 0.684 rs4886816 chr15:76874707 A/C cg23625390 chr15:77176239 SCAPER -0.37 -4.67 -0.39 7.71e-6 Blood metabolite levels; TGCT trans rs6951245 0.554 rs11761322 chr7:1151657 A/G cg13565492 chr6:43139072 SRF -0.81 -7.71 -0.57 3.45e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6952808 0.595 rs3778982 chr7:2166233 T/C cg04267008 chr7:1944627 MAD1L1 -0.38 -5.19 -0.42 8.33e-7 Bipolar disorder and schizophrenia; TGCT cis rs6429082 0.702 rs7532018 chr1:235706290 C/T cg26050004 chr1:235667680 B3GALNT2 -0.58 -4.93 -0.4 2.55e-6 Adiposity; TGCT cis rs950776 0.518 rs8053 chr15:78841220 T/C cg06917634 chr15:78832804 PSMA4 -0.93 -9.08 -0.63 2.07e-15 Sudden cardiac arrest; TGCT cis rs75686122 0.892 rs79580171 chr8:104514299 T/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs34734847 1.000 rs3752531 chr12:121157851 A/G cg21892295 chr12:121157589 UNC119B -0.23 -5.52 -0.44 1.89e-7 Mean corpuscular volume; TGCT cis rs6089584 0.850 rs6142939 chr20:60627729 A/G cg06108461 chr20:60628389 TAF4 -0.75 -11.03 -0.7 3.95e-20 Body mass index; TGCT cis rs9811920 0.683 rs813218 chr3:99592596 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.45 -5.33 -0.43 4.52e-7 Axial length; TGCT cis rs10875595 0.836 rs59933130 chr5:140667303 G/A cg20560182 chr5:140700478 TAF7 -0.64 -4.96 -0.41 2.26e-6 Pulmonary function decline; TGCT cis rs17401966 0.928 rs11121531 chr1:10277357 G/A cg21474053 chr1:11182049 MTOR 0.19 4.49 0.37 1.58e-5 Hepatocellular carcinoma; TGCT cis rs2224391 0.628 rs2773311 chr6:5250866 A/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs8180040 0.654 rs4682831 chr3:47027138 A/G cg27129171 chr3:47204927 SETD2 -0.7 -8.8 -0.62 9.59e-15 Colorectal cancer; TGCT cis rs17761864 0.718 rs8064885 chr17:2047564 G/A cg02171503 chr17:1588363 PRPF8 -0.5 -4.79 -0.4 4.7e-6 Esophageal cancer (squamous cell); TGCT cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg22105103 chr4:187893119 NA 0.33 4.62 0.38 9.41e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs4650994 0.525 rs17361286 chr1:178521916 C/G cg05059571 chr16:84539110 KIAA1609 -0.53 -10.92 -0.7 7.49e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4927850 0.881 rs7624638 chr3:195748729 C/T cg12923728 chr3:195709715 SDHAP1 -0.36 -7.58 -0.56 6.91e-12 Pancreatic cancer; TGCT cis rs12039431 0.788 rs61776188 chr1:38021326 C/T cg17933807 chr1:38061675 GNL2 -0.81 -7.89 -0.58 1.34e-12 Epithelial ovarian cancer; TGCT cis rs9549367 0.789 rs6577035 chr13:113879997 G/A cg00898013 chr13:113819073 PROZ -0.39 -4.78 -0.39 4.78e-6 Platelet distribution width; TGCT cis rs10779751 0.734 rs1148485 chr1:11148759 G/A cg08854313 chr1:11322531 MTOR 0.89 7.18 0.54 5.5e-11 Body mass index; TGCT cis rs116095464 0.558 rs10068203 chr5:206618 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.72 4.52 0.38 1.4e-5 Breast cancer; TGCT cis rs12477438 0.798 rs4850891 chr2:99574642 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.58 -0.61 3.24e-14 Chronic sinus infection; TGCT cis rs1008375 0.646 rs13146455 chr4:17565617 T/G cg16339924 chr4:17578868 LAP3 -0.79 -6.56 -0.51 1.33e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7829975 0.633 rs2979181 chr8:8323088 A/T cg08975724 chr8:8085496 FLJ10661 0.62 5.97 0.47 2.37e-8 Mood instability; TGCT trans rs916888 0.610 rs199442 chr17:44820122 G/A cg22433210 chr17:43662623 NA 0.96 7.9 0.58 1.29e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9389248 0.690 rs6569982 chr6:135256495 C/G cg24558204 chr6:135376177 HBS1L 0.47 4.75 0.39 5.43e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs6840360 0.593 rs4696286 chr4:152606547 G/A cg17479576 chr4:152424074 FAM160A1 -0.61 -6.29 -0.49 4.86e-9 Intelligence (multi-trait analysis); TGCT cis rs2288073 0.965 rs13395596 chr2:24410738 T/C cg02683114 chr2:24398427 C2orf84 -0.24 -5.72 -0.46 7.53e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs1023500 0.505 rs134886 chr22:42673856 C/T cg15557168 chr22:42548783 NA 0.2 4.75 0.39 5.56e-6 Schizophrenia; TGCT cis rs13256369 0.802 rs13255789 chr8:8562791 T/C cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs6570726 0.846 rs426874 chr6:145880630 A/C cg05347473 chr6:146136440 FBXO30 0.52 4.96 0.41 2.28e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs8177179 0.967 rs10935085 chr3:133459735 C/T cg16262614 chr3:133464971 TF 0.34 4.62 0.38 9.28e-6 Iron status biomarkers (transferrin levels); TGCT cis rs1981331 1.000 rs1981331 chr21:47995443 A/C cg23283320 chr21:48055893 PRMT2 1.29 6.09 0.48 1.31e-8 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg03806693 chr22:41940476 POLR3H 1.14 12.91 0.76 1.07e-24 Vitiligo; TGCT cis rs6918586 0.658 rs198829 chr6:26118893 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.68 -6.46 -0.5 2.15e-9 Schizophrenia; TGCT cis rs12701220 0.894 rs34712249 chr7:1036634 C/T cg07217954 chr7:1067459 C7orf50 -0.48 -4.75 -0.39 5.49e-6 Bronchopulmonary dysplasia; TGCT cis rs12220238 0.722 rs4745750 chr10:76394003 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.64 5.19 0.42 8.46e-7 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7714584 1.000 rs7715981 chr5:150258107 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs3820068 0.608 rs12760450 chr1:16037282 G/A cg05660106 chr1:15850417 CASP9 0.68 6.34 0.49 3.98e-9 Systolic blood pressure; TGCT cis rs7267979 0.873 rs6037062 chr20:25202892 G/A cg16686733 chr20:25566563 NINL 0.55 5.71 0.46 7.87e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11688237 0.805 rs10175481 chr2:144545138 T/C cg07409629 chr2:144282743 ARHGAP15 -0.39 -4.78 -0.39 4.83e-6 Chin dimples; TGCT cis rs735396 0.770 rs1169300 chr12:121431225 G/A cg02403541 chr12:121454288 C12orf43 0.73 6.5 0.5 1.76e-9 N-glycan levels; TGCT cis rs7246657 0.722 rs2909102 chr19:38167364 C/T cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT cis rs864643 0.812 rs59673755 chr3:39545992 C/G cg14968361 chr3:39543547 MOBP 0.44 4.63 0.38 9e-6 Attention deficit hyperactivity disorder; TGCT cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs35146811 0.735 rs2272344 chr7:99786819 C/T cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs6087771 0.642 rs6060403 chr20:30221104 C/A cg21427119 chr20:30132790 HM13 -0.3 -5.05 -0.41 1.53e-6 Subcortical brain region volumes;Putamen volume; TGCT cis rs6964587 0.869 rs7778667 chr7:91520816 C/G cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs896854 0.596 rs7823059 chr8:95974961 T/C cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg04237666 chr4:83674615 SCD5;MIR575 0.6 6.62 0.51 9.65e-10 Breast cancer; TGCT cis rs2404602 0.735 rs2957614 chr15:76696635 C/T cg22467129 chr15:76604101 ETFA -0.45 -4.65 -0.39 8.35e-6 Blood metabolite levels; TGCT cis rs7178572 0.568 rs11072643 chr15:77415508 T/A cg15453836 chr15:77711506 NA 0.42 4.75 0.39 5.48e-6 Type 2 diabetes; TGCT cis rs13118159 0.771 rs13117476 chr4:1334721 A/G cg13395646 chr4:1353034 KIAA1530 -0.41 -4.72 -0.39 6.23e-6 Longevity; TGCT cis rs3784262 0.643 rs12916872 chr15:58375741 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.13 -0.48 1.07e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9902453 0.935 rs9898424 chr17:28392946 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.54 -0.51 1.42e-9 Coffee consumption (cups per day); TGCT cis rs3540 0.533 rs2256097 chr15:90971331 A/T cg22089800 chr15:90895588 ZNF774 0.76 8.16 0.59 3.24e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs11969893 0.737 rs1854483 chr6:101378117 G/A cg12253828 chr6:101329408 ASCC3 1.21 6.03 0.48 1.74e-8 Economic and political preferences (immigration/crime); TGCT cis rs56104184 0.830 rs45589039 chr19:49355385 C/T cg15549821 chr19:49342101 PLEKHA4 -0.84 -10.28 -0.68 2.68e-18 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs10838634 1.000 rs7945548 chr11:46900280 A/G cg18332754 chr11:46939436 LRP4 0.89 4.77 0.39 5.13e-6 Schizophrenia; TGCT cis rs9467773 0.933 rs2024970 chr6:26497520 T/A cg09904177 chr6:26538194 HMGN4 0.57 5.15 0.42 9.82e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs59751489 chr4:98933802 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10851411 0.954 rs34643746 chr15:42861567 A/G cg23803468 chr15:43513504 EPB42 0.27 5.19 0.42 8.38e-7 Glucose homeostasis traits; TGCT cis rs7223966 1.000 rs6504171 chr17:61710010 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.76 0.39 5.24e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1552244 1.000 rs66838678 chr3:10150350 G/A cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs9916302 0.904 rs7503069 chr17:37697128 C/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs36051895 0.659 rs12343065 chr9:5083533 C/T cg02405213 chr9:5042618 JAK2 -0.78 -10.36 -0.68 1.65e-18 Pediatric autoimmune diseases; TGCT cis rs554111 0.891 rs604645 chr1:21043926 T/C cg08890418 chr1:21044141 KIF17 0.59 6.19 0.49 8.06e-9 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs7666738 0.830 rs34671152 chr4:98978177 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1775715 0.737 rs2808072 chr10:32205504 A/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6964587 1.000 rs35653487 chr7:91745441 C/G cg22709100 chr7:91322751 NA 0.29 4.66 0.39 8e-6 Breast cancer; TGCT cis rs9549367 0.713 rs510160 chr13:113822481 A/G cg18105134 chr13:113819100 PROZ 0.47 8.15 0.59 3.4e-13 Platelet distribution width; TGCT cis rs6121246 0.567 rs7361893 chr20:30200751 C/T cg21427119 chr20:30132790 HM13 -0.39 -5.61 -0.45 1.25e-7 Mean corpuscular hemoglobin; TGCT cis rs67311347 1.000 rs6599094 chr3:40399593 A/G cg13683864 chr3:40499215 RPL14 -1.02 -10.8 -0.7 1.43e-19 Renal cell carcinoma; TGCT trans rs114540395 0.858 rs7073902 chr10:103291893 A/C cg10198749 chr1:39920707 MACF1 0.55 7.05 0.53 1.11e-10 Schizophrenia; TGCT cis rs12049351 0.774 rs12125125 chr1:229627666 A/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs72615157 0.716 rs75779608 chr7:99768957 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.69 5.42 0.44 3.04e-7 Lung function (FEV1/FVC); TGCT cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg23758822 chr17:41437982 NA 0.72 6.77 0.52 4.51e-10 Menopause (age at onset); TGCT cis rs514406 0.861 rs11206026 chr1:53281708 G/A cg24675658 chr1:53192096 ZYG11B -0.68 -7.71 -0.57 3.45e-12 Monocyte count; TGCT cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT trans rs916888 0.779 rs199528 chr17:44843136 C/T cg22968622 chr17:43663579 NA 1.24 11.44 0.72 3.96e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3784262 0.527 rs1441815 chr15:58274229 A/C cg12031962 chr15:58353849 ALDH1A2 -0.36 -5.16 -0.42 9.33e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6840360 0.967 rs4696105 chr4:152606702 T/G cg17479576 chr4:152424074 FAM160A1 -0.48 -5.17 -0.42 9.03e-7 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.510 rs55750776 chr5:230467 T/C cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs10838634 1.000 rs10466477 chr11:46782472 C/A cg18332754 chr11:46939436 LRP4 0.84 4.54 0.38 1.29e-5 Schizophrenia; TGCT cis rs7666738 0.546 rs13148080 chr4:98680947 A/G cg18180107 chr4:99064573 C4orf37 0.54 4.73 0.39 5.89e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 0.692 rs7529674 chr1:46818508 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs6121246 0.909 rs7354225 chr20:30296881 C/T cg13852791 chr20:30311386 BCL2L1 0.68 4.79 0.4 4.6e-6 Mean corpuscular hemoglobin; TGCT cis rs7662987 0.517 rs2602872 chr4:100038996 A/G cg12011299 chr4:100065546 ADH4 0.39 4.7 0.39 6.79e-6 Smoking initiation; TGCT cis rs2067615 0.524 rs4246257 chr12:107062329 C/T cg15890332 chr12:107067104 RFX4 0.28 5.56 0.45 1.59e-7 Heart rate; TGCT cis rs6748734 0.817 rs10182575 chr2:241806690 C/T cg04034577 chr2:241836375 C2orf54 -0.38 -6.02 -0.48 1.85e-8 Urinary metabolites; TGCT cis rs736408 1.000 rs736408 chr3:52835354 C/T cg07507251 chr3:52567010 NT5DC2 0.45 6.03 0.48 1.78e-8 Bipolar disorder; TGCT cis rs7267979 0.966 rs454723 chr20:25438928 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2463822 0.583 rs72919477 chr11:62042403 G/C cg06239285 chr11:62104954 ASRGL1 -0.84 -5.17 -0.42 9.26e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs597539 0.617 rs686348 chr11:68636996 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9322193 0.923 rs12174349 chr6:150039148 G/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs911263 0.961 rs1957570 chr14:68729224 A/C cg18825221 chr14:68749962 RAD51L1 -0.28 -5.64 -0.45 1.1e-7 Primary biliary cholangitis; TGCT cis rs12210905 0.688 rs57075114 chr6:27491169 T/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7726839 0.561 rs3915384 chr5:573395 G/T cg20362242 chr5:692897 TPPP 0.48 4.59 0.38 1.06e-5 Obesity-related traits; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg24846343 chr22:24311635 DDTL 0.19 4.64 0.38 8.9e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467711 0.606 rs13212985 chr6:26609989 G/C cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs7302981 0.967 rs2178173 chr12:50517929 A/G cg23855989 chr12:50355821 AQP5 -0.3 -4.44 -0.37 2e-5 Systolic blood pressure; TGCT cis rs7677751 0.806 rs1800810 chr4:55094031 C/G cg17187183 chr4:55093834 PDGFRA 0.53 6.92 0.53 2.19e-10 Corneal astigmatism; TGCT cis rs7819412 0.775 rs4841490 chr8:10936891 T/C cg21775007 chr8:11205619 TDH -0.5 -4.61 -0.38 9.83e-6 Triglycerides; TGCT cis rs2251381 0.640 rs2183568 chr21:30484782 A/T cg24692254 chr21:30365293 RNF160 -0.84 -8.55 -0.61 3.89e-14 Selective IgA deficiency; TGCT cis rs9902453 0.934 rs8079028 chr17:28484234 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs9814567 1.000 rs7619451 chr3:134233238 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -1.04 -8.2 -0.59 2.56e-13 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg11062466 chr8:58055876 NA 0.38 4.5 0.37 1.56e-5 Developmental language disorder (linguistic errors); TGCT cis rs1865760 0.865 rs4478388 chr6:25953633 A/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs6500602 0.627 rs4786494 chr16:4506232 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.37 0.55 2.06e-11 Schizophrenia; TGCT cis rs12478296 0.892 rs11893879 chr2:243010411 G/A cg06360820 chr2:242988706 NA -0.62 -5.23 -0.43 6.93e-7 Obesity-related traits; TGCT cis rs62380364 0.602 rs591228 chr5:88064809 G/A cg24804195 chr5:87968844 LOC645323 -0.58 -5.69 -0.45 8.73e-8 Intelligence (multi-trait analysis); TGCT cis rs2073300 1.000 rs61080017 chr20:23457569 A/G cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs782590 0.967 rs1084522 chr2:55843294 A/G cg18811423 chr2:55921094 PNPT1 0.63 6.81 0.52 3.75e-10 Metabolic syndrome; TGCT cis rs7439150 0.955 rs2227398 chr4:155485138 G/A cg22130008 chr4:155548532 NA -0.47 -5.8 -0.46 5.25e-8 Fibrinogen levels; TGCT cis rs6604026 0.524 rs532834 chr1:93468062 A/T cg17283838 chr1:93427260 FAM69A 0.54 4.58 0.38 1.1e-5 Multiple sclerosis; TGCT cis rs4319547 0.915 rs11058402 chr12:122981053 A/G cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.32 -0.43 4.71e-7 Body mass index; TGCT cis rs11105298 0.891 rs11105312 chr12:89920733 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9611565 0.649 rs202655 chr22:41841564 G/C cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Vitiligo; TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs875971 0.862 rs6964437 chr7:65686444 A/G cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.94e-6 Aortic root size; TGCT cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg11502198 chr6:26597334 ABT1 0.55 4.89 0.4 3.05e-6 Intelligence (multi-trait analysis); TGCT cis rs10979314 1.000 rs10979314 chr9:111072429 A/G cg14131431 chr9:110093467 RAD23B -0.47 -4.56 -0.38 1.23e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs17376456 0.825 rs10038831 chr5:93124115 C/T cg21475434 chr5:93447410 FAM172A 0.63 4.92 0.4 2.72e-6 Diabetic retinopathy; TGCT cis rs11578119 0.667 rs10919394 chr1:170389788 T/C cg09767346 chr1:170501363 GORAB -0.57 -4.7 -0.39 6.94e-6 Male-pattern baldness; TGCT cis rs3892630 0.878 rs6510277 chr19:33183669 C/A cg22980127 chr19:33182716 NUDT19 0.7 5.18 0.42 8.9e-7 Red blood cell traits; TGCT cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg03264133 chr6:25882463 NA -0.64 -5.88 -0.47 3.52e-8 Intelligence (multi-trait analysis); TGCT trans rs4129566 0.641 rs71609829 chr4:174519719 G/A cg01401824 chr2:159902017 TANC1 0.69 7.24 0.55 4.07e-11 Cocaine dependence; TGCT cis rs62064224 0.702 rs2302277 chr17:30791509 C/G cg18200150 chr17:30822561 MYO1D 0.6 8.56 0.61 3.73e-14 Schizophrenia; TGCT cis rs797680 0.930 rs2295423 chr1:93581024 T/C cg17826107 chr1:92977322 EVI5 -0.22 -5.04 -0.41 1.59e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs67311347 1.000 rs4973998 chr3:40460352 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs7714584 1.000 rs75294883 chr5:150196503 T/C cg22134413 chr5:150180641 NA 1.09 7.71 0.57 3.43e-12 Crohn's disease; TGCT cis rs4654899 1.000 rs3767248 chr1:21276854 A/G cg01072550 chr1:21505969 NA -0.49 -7.62 -0.56 5.82e-12 Superior frontal gyrus grey matter volume; TGCT cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg00786635 chr1:25594202 NA 0.56 5.95 0.47 2.54e-8 Erythrocyte sedimentation rate; TGCT cis rs951366 0.873 rs823118 chr1:205723572 C/T cg17178900 chr1:205818956 PM20D1 0.41 4.56 0.38 1.22e-5 Menarche (age at onset); TGCT cis rs916888 0.821 rs199509 chr17:44858728 G/A cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9818758 0.607 rs9990153 chr3:49291883 C/T cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.95 7.54 0.56 8.47e-12 Platelet count; TGCT cis rs4919044 0.808 rs12416051 chr10:94788835 C/T cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT trans rs11088226 0.681 rs11700671 chr21:33938621 T/A cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT cis rs1670533 1.000 rs10003009 chr4:1050849 G/A cg27284194 chr4:1044797 NA 0.68 5.87 0.47 3.76e-8 Recombination rate (females); TGCT cis rs7666738 0.606 rs4699611 chr4:99097492 T/G cg17366294 chr4:99064904 C4orf37 0.53 4.9 0.4 2.89e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.548 rs2320740 chr12:38166421 G/A cg13010199 chr12:38710504 ALG10B 0.62 4.89 0.4 3.09e-6 Bladder cancer; TGCT cis rs751728 0.717 rs2281816 chr6:33772335 A/G cg00334056 chr6:33755658 LEMD2 -0.27 -4.91 -0.4 2.85e-6 Crohn's disease; TGCT cis rs2153535 0.580 rs1832101 chr6:8460177 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs986417 0.786 rs2038277 chr14:61083662 G/A cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs9303401 0.538 rs8078280 chr17:56473132 A/G cg25039879 chr17:56429692 SUPT4H1 0.55 4.88 0.4 3.26e-6 Cognitive test performance; TGCT cis rs9393777 0.588 rs11967935 chr6:26560672 A/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.49 -4.52 -0.38 1.41e-5 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg20203395 chr5:56204925 C5orf35 -0.57 -4.8 -0.4 4.5e-6 Initial pursuit acceleration; TGCT cis rs9399135 0.660 rs4440481 chr6:135276696 A/G cg24558204 chr6:135376177 HBS1L 0.47 5.13 0.42 1.09e-6 Red blood cell count; TGCT cis rs6570726 0.791 rs365869 chr6:145884751 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6684514 1.000 rs12022194 chr1:156312331 T/A cg20302342 chr1:156215951 PAQR6 0.36 4.77 0.39 5.1e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs981844 0.740 rs12644642 chr4:154686550 G/C cg14289246 chr4:154710475 SFRP2 -0.91 -8.31 -0.6 1.38e-13 Response to statins (LDL cholesterol change); TGCT cis rs12510870 0.599 rs66494307 chr4:74448561 G/A cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs1371867 0.875 rs962452 chr8:101331369 G/A cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs6725041 0.819 rs10172865 chr2:213089339 G/A cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs3087591 0.960 rs4435317 chr17:29436512 G/C cg24425628 chr17:29625626 OMG;NF1 0.47 7.35 0.55 2.37e-11 Hip circumference; TGCT cis rs7681440 1.000 rs7681440 chr4:90756550 C/G cg26578617 chr4:90757533 SNCA 0.46 4.79 0.4 4.59e-6 Dementia with Lewy bodies; TGCT cis rs6089584 0.888 rs6061983 chr20:60621202 T/C cg13770153 chr20:60521292 NA -0.54 -7.12 -0.54 7.73e-11 Body mass index; TGCT cis rs6089829 0.962 rs7273930 chr20:61666017 G/A cg02380750 chr20:61661411 NA 0.35 6.27 0.49 5.56e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs40363 0.620 rs1137454 chr16:3533577 C/G cg05754148 chr16:3507555 NAT15 -0.43 -5.2 -0.42 7.94e-7 Tuberculosis; TGCT cis rs7666738 0.830 rs6846229 chr4:99016546 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg15242686 chr22:24348715 GSTTP1 0.49 5.98 0.47 2.17e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7772486 0.754 rs2328707 chr6:146053498 G/A cg23711669 chr6:146136114 FBXO30 -0.95 -10.87 -0.7 9.46e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.861 rs28829607 chr4:98964325 G/C cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10782582 0.609 rs1630587 chr1:76399787 T/C cg03433033 chr1:76189801 ACADM -0.52 -5.13 -0.42 1.07e-6 Daytime sleep phenotypes; TGCT cis rs2439831 0.867 rs12443102 chr15:43932103 G/C cg19166733 chr15:44192098 FRMD5 -0.24 -4.78 -0.39 4.85e-6 Lung cancer in ever smokers; TGCT cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 7.92e-6 Prudent dietary pattern; TGCT cis rs3935685 1.000 rs62007780 chr15:78025464 G/T cg25212270 chr15:78015279 NA 0.31 6.23 0.49 6.71e-9 Intelligence (multi-trait analysis); TGCT cis rs9910055 0.540 rs609292 chr17:42180436 G/A cg19774624 chr17:42201019 HDAC5 0.73 7.1 0.54 8.3e-11 Total body bone mineral density; TGCT cis rs9611565 0.694 rs202617 chr22:41822793 C/T cg17554472 chr22:41940697 POLR3H 0.6 5.34 0.43 4.31e-7 Vitiligo; TGCT cis rs9787249 0.957 rs2274949 chr1:40221067 G/A cg19912559 chr1:40204330 PPIE 0.47 5.52 0.44 1.88e-7 Blood protein levels; TGCT cis rs155076 0.711 rs9550724 chr13:21885030 G/T cg25811766 chr13:21894605 NA 0.32 4.53 0.38 1.36e-5 White matter hyperintensity burden; TGCT cis rs7095607 0.606 rs6480312 chr10:69957845 C/T cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 -0.39 -5.3 -0.43 5.09e-7 Lymphocyte counts; TGCT cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg21672276 chr3:44754072 ZNF502 -0.41 -4.66 -0.39 7.99e-6 Depressive symptoms; TGCT cis rs1552244 1.000 rs6442148 chr3:10078289 G/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs2576037 0.583 rs8098948 chr18:44512332 C/A cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.68 -0.39 7.26e-6 Personality dimensions; TGCT cis rs6700896 0.522 rs67620752 chr1:66157269 T/C cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7666738 0.830 rs6817645 chr4:99016054 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs1005277 0.579 rs11011461 chr10:38431427 G/A cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs919433 0.617 rs700646 chr2:198608511 C/T cg00792783 chr2:198669748 PLCL1 0.55 4.89 0.4 3.04e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs7226408 0.842 rs11662247 chr18:34348510 A/G cg06757138 chr18:34340585 FHOD3 0.29 5.15 0.42 1.01e-6 Obesity-related traits; TGCT cis rs2153535 0.584 rs9502721 chr6:8541379 G/A cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.46e-7 Motion sickness; TGCT cis rs7267979 0.868 rs6107019 chr20:25233985 C/T cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11642862 0.901 rs77604316 chr16:30921487 G/A cg01031475 chr16:30004376 HIRIP3 0.23 4.54 0.38 1.34e-5 Tonsillectomy; TGCT trans rs7613875 0.620 rs17657664 chr3:50032008 T/G cg21665057 chr3:196295764 WDR53;FBXO45 0.83 8.71 0.62 1.65e-14 Body mass index; TGCT cis rs8017423 0.967 rs6575120 chr14:90725094 C/T cg04374321 chr14:90722782 PSMC1 0.73 7.63 0.57 5.38e-12 Mortality in heart failure; TGCT cis rs7267979 1.000 rs2257988 chr20:25270003 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs875971 0.862 rs949930 chr7:65766822 C/G cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.27e-7 Aortic root size; TGCT cis rs916888 0.610 rs199453 chr17:44800946 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.59 4.61 0.38 9.8200000000000008e-06 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg24549020 chr5:56110836 MAP3K1 0.65 5.51 0.44 2.01e-7 Initial pursuit acceleration; TGCT cis rs9611565 0.840 rs4822025 chr22:41776646 C/G cg17554472 chr22:41940697 POLR3H -0.49 -5.17 -0.42 9.2e-7 Vitiligo; TGCT cis rs17376456 0.825 rs10051878 chr5:93064164 T/G cg21475434 chr5:93447410 FAM172A 0.63 4.77 0.39 5.03e-6 Diabetic retinopathy; TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg11965913 chr1:205819406 PM20D1 0.51 7.19 0.54 5.34e-11 Menarche (age at onset); TGCT cis rs9653442 1.000 rs1160542 chr2:100832155 A/G cg22139774 chr2:100720529 AFF3 0.42 7.51 0.56 1.02e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1997103 1.000 rs6968966 chr7:55411356 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs4689388 0.853 rs13103357 chr4:6294544 A/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg12310025 chr6:25882481 NA 0.9 9.29 0.64 6.69e-16 Blood metabolite levels; TGCT cis rs950169 0.686 rs12906474 chr15:85109237 A/G cg17173187 chr15:85201210 NMB 0.45 4.55 0.38 1.24e-5 Schizophrenia; TGCT cis rs8084125 1.000 rs72978665 chr18:74953641 A/G cg07390210 chr18:74961196 GALR1 0.38 4.63 0.38 9.21e-6 Obesity-related traits; TGCT cis rs2070488 0.965 rs7642472 chr3:38525567 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 8.99 0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs259282 0.692 rs17693106 chr19:33125055 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.62 -5.77 -0.46 5.84e-8 Schizophrenia; TGCT cis rs11085466 1.000 rs2292986 chr19:21776332 A/C cg23026602 chr19:21646605 NA 0.54 4.81 0.4 4.25e-6 Colorectal or endometrial cancer; TGCT cis rs2576037 0.583 rs9947131 chr18:44534769 G/T cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.78 -0.39 4.94e-6 Personality dimensions; TGCT cis rs362296 0.698 rs3135168 chr4:3262699 T/C cg06533319 chr4:3265114 C4orf44 0.24 4.74 0.39 5.7e-6 Parental longevity (mother's age at death); TGCT cis rs7267979 0.899 rs6115213 chr20:25550372 G/A cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7586879 0.789 rs17046737 chr2:25127835 C/T cg01884057 chr2:25150051 NA 0.27 4.72 0.39 6.29e-6 Body mass index; TGCT cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg11301795 chr4:187892539 NA -0.34 -5.2 -0.42 7.94e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4389656 0.740 rs412643 chr5:6720715 A/G cg10857441 chr5:6722123 POLS -0.22 -4.86 -0.4 3.44e-6 Coronary artery disease; TGCT cis rs6912958 0.781 rs9450752 chr6:88300013 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs909674 0.514 rs7423 chr22:39781429 C/T cg02038168 chr22:39784481 NA -0.73 -6.35 -0.5 3.77e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10489202 0.632 rs6659713 chr1:168072249 G/T cg24449463 chr1:168025552 DCAF6 0.49 5.59 0.45 1.36e-7 Schizophrenia; TGCT cis rs7772486 0.790 rs9403750 chr6:146167762 G/A cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.61e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs3845702 1.000 rs3768839 chr2:180835992 G/A cg01881094 chr2:180872142 CWC22 -0.66 -5.84 -0.46 4.29e-8 Schizophrenia; TGCT cis rs992157 1.000 rs2292553 chr2:219146803 G/A cg00012203 chr2:219082015 ARPC2 0.78 8.41 0.6 8.04e-14 Colorectal cancer; TGCT cis rs4253772 0.591 rs9615348 chr22:46729338 C/G cg24881330 chr22:46731750 TRMU 0.96 4.79 0.4 4.65e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs6840360 0.870 rs7680604 chr4:152469917 C/T cg17479576 chr4:152424074 FAM160A1 -0.45 -4.88 -0.4 3.15e-6 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.623 rs170051 chr17:28914153 G/A cg14008862 chr17:28927542 LRRC37B2 0.93 5.64 0.45 1.11e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs35306767 0.953 rs35174953 chr10:961191 C/A cg26597838 chr10:835615 NA 0.66 9.01 0.63 3.04e-15 Eosinophil percentage of granulocytes; TGCT cis rs7552404 0.655 rs5745336 chr1:76273519 G/A cg22875332 chr1:76189707 ACADM 0.64 6.9 0.53 2.32e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3087591 0.960 rs2905793 chr17:29470072 C/T cg24425628 chr17:29625626 OMG;NF1 0.49 7.74 0.57 2.97e-12 Hip circumference; TGCT cis rs9486719 0.857 rs4839833 chr6:96882069 T/C cg18709589 chr6:96969512 KIAA0776 0.75 6.3 0.49 4.73e-9 Migraine;Coronary artery disease; TGCT cis rs2404602 1.000 rs11072603 chr15:76881138 G/T cg22467129 chr15:76604101 ETFA -0.44 -4.86 -0.4 3.41e-6 Blood metabolite levels; TGCT cis rs4727443 0.866 rs13238380 chr7:99629061 C/T cg13334819 chr7:99746414 C7orf59 0.56 4.71 0.39 6.63e-6 Interstitial lung disease; TGCT cis rs71435601 0.699 rs563290 chr2:21288226 G/A cg00673290 chr2:21266727 APOB 0.64 4.54 0.38 1.33e-5 Cholesterol, total; TGCT trans rs2727020 0.658 rs10839278 chr11:49450847 G/C cg03929089 chr4:120376271 NA -0.77 -9.03 -0.63 2.74e-15 Coronary artery disease; TGCT cis rs5769707 0.839 rs73176988 chr22:49989649 G/T cg20744362 chr22:50050164 C22orf34 0.27 4.55 0.38 1.25e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7267979 1.000 rs2027003 chr20:25350498 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs637571 0.522 rs538954 chr11:65756808 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.68 6.74 0.52 5.42e-10 Eosinophil percentage of white cells; TGCT cis rs3820928 0.874 rs1949807 chr2:227891861 A/G cg11843606 chr2:227700838 RHBDD1 -0.5 -4.63 -0.38 9.22e-6 Pulmonary function; TGCT cis rs478304 0.651 rs4014192 chr11:65498915 C/T cg27068330 chr11:65405492 SIPA1 -0.94 -9.4 -0.65 3.49e-16 Acne (severe); TGCT cis rs7726839 0.540 rs72703078 chr5:594987 A/C cg16624210 chr5:671434 TPPP 0.45 4.92 0.4 2.71e-6 Obesity-related traits; TGCT cis rs2836950 0.545 rs2836940 chr21:40588696 T/C cg06238570 chr21:40685208 BRWD1 -0.6 -6.3 -0.49 4.8e-9 Menarche (age at onset); TGCT cis rs13082711 0.554 rs73055750 chr3:27401505 C/G cg02860705 chr3:27208620 NA 0.42 5.81 0.46 4.86e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7940866 0.874 rs10894306 chr11:130873882 A/C cg12179176 chr11:130786555 SNX19 0.58 5.69 0.46 8.66e-8 Schizophrenia; TGCT cis rs1008375 0.931 rs6813374 chr4:17649494 T/C cg16339924 chr4:17578868 LAP3 0.67 5.55 0.45 1.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs986417 1.000 rs1956554 chr14:60963775 C/T cg27398547 chr14:60952738 C14orf39 -1.49 -10.81 -0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs629922 0.642 rs615119 chr11:114072224 T/C cg01914181 chr11:114070210 ZBTB16 0.27 4.74 0.39 5.65e-6 Paneth cell defects in Crohn's disease; TGCT cis rs8177253 0.896 rs34252038 chr3:133490621 G/T cg11941060 chr3:133502564 NA -0.29 -6.18 -0.49 8.57e-9 Iron status biomarkers; TGCT cis rs1552244 0.572 rs6785976 chr3:10168647 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.0 -0.47 2.01e-8 Alzheimer's disease; TGCT cis rs74054849 0.717 rs61348093 chr1:15922742 T/G cg05660106 chr1:15850417 CASP9 0.94 4.83 0.4 3.93e-6 Alcoholic chronic pancreatitis; TGCT cis rs11190604 1.000 rs12355721 chr10:102244911 C/T cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs208520 0.789 rs9351549 chr6:66871851 A/G cg07460842 chr6:66804631 NA -0.91 -9.43 -0.65 2.99e-16 Exhaled nitric oxide output; TGCT cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg20891558 chr2:74357851 NA 0.64 9.46 0.65 2.56e-16 Gestational age at birth (maternal effect); TGCT cis rs916888 0.531 rs183211 chr17:44788310 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.6 4.66 0.39 8.02e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs17450420 1.000 rs74240931 chr13:105056429 G/A cg14737571 chr13:113436568 ATP11A 0.61 6.64 0.51 8.8e-10 Esophageal cancer (alcohol interaction); TGCT cis rs877282 1.000 rs7100358 chr10:773681 G/A cg17470449 chr10:769945 NA 0.3 4.79 0.39 4.71e-6 Uric acid levels; TGCT cis rs4478858 0.647 rs11581476 chr1:31717675 C/T cg00250761 chr1:31883323 NA -0.28 -4.97 -0.41 2.2e-6 Alcohol dependence; TGCT cis rs1218582 0.688 rs2135219 chr1:154857217 G/A cg09359103 chr1:154839909 KCNN3 -0.67 -12.84 -0.76 1.57e-24 Prostate cancer; TGCT cis rs8180040 0.966 rs11711824 chr3:47468261 C/T cg27129171 chr3:47204927 SETD2 0.66 7.98 0.58 8.4e-13 Colorectal cancer; TGCT cis rs6951245 0.678 rs28600085 chr7:1169636 C/T cg23708337 chr7:1209742 NA 0.55 5.47 0.44 2.34e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7296418 0.619 rs7139321 chr12:123719528 T/G cg00376283 chr12:123451042 ABCB9 0.7 6.27 0.49 5.58e-9 Platelet count; TGCT cis rs739496 0.615 rs7962138 chr12:112180177 A/G cg10833066 chr12:111807467 FAM109A 0.37 5.02 0.41 1.74e-6 Platelet count; TGCT cis rs7666738 0.830 rs11938686 chr4:98964470 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.0 0.41 1.9e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs782590 0.967 rs17278044 chr2:55748217 G/C cg03859395 chr2:55845619 SMEK2 0.93 11.51 0.72 2.7e-21 Metabolic syndrome; TGCT cis rs67072384 1.000 rs11235579 chr11:72453095 A/G cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs6558530 0.932 rs7846610 chr8:1706675 C/T cg09410841 chr8:1729607 CLN8 0.89 9.79 0.66 4.05e-17 Systolic blood pressure; TGCT trans rs208520 0.802 rs851600 chr6:66893754 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -10.32 -0.68 2.12e-18 Exhaled nitric oxide output; TGCT cis rs7208859 0.623 rs11657662 chr17:29076347 A/G cg14008862 chr17:28927542 LRRC37B2 -0.77 -4.61 -0.38 9.76e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs8013055 0.898 rs8014913 chr14:105977313 T/C cg25008857 chr14:105974488 NA 0.27 4.65 0.39 8.35e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7267979 0.586 rs6050445 chr20:25195394 C/T cg16686733 chr20:25566563 NINL 0.55 5.52 0.44 1.88e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.6 -6.01 -0.48 1.91e-8 Bipolar disorder; TGCT cis rs2032447 0.966 rs7756117 chr6:26046565 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.5 4.79 0.39 4.74e-6 Intelligence (multi-trait analysis); TGCT cis rs42648 0.748 rs10225744 chr7:89946003 T/C cg25739043 chr7:89950458 NA -0.63 -6.04 -0.48 1.64e-8 Homocysteine levels; TGCT cis rs7666738 0.791 rs10033211 chr4:98995624 T/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6912958 0.781 rs1051148 chr6:88221892 T/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs13108904 0.967 rs11727167 chr4:1285521 A/G cg13342137 chr4:2252803 MXD4 0.17 4.58 0.38 1.09e-5 Obesity-related traits; TGCT cis rs3087591 0.708 rs2107359 chr17:29697223 A/T cg24425628 chr17:29625626 OMG;NF1 0.39 5.69 0.46 8.47e-8 Hip circumference; TGCT cis rs7312933 0.558 rs1669936 chr12:42813509 C/A cg19980929 chr12:42632907 YAF2 -0.4 -5.7 -0.46 8.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2723064 0.516 rs2901749 chr2:65292570 G/T cg05010058 chr2:65284262 CEP68 0.47 4.48 0.37 1.66e-5 Atrial fibrillation; TGCT trans rs7088591 0.702 rs10491208 chr10:59703352 C/G cg05779219 chr20:23032166 NA 1.2 7.39 0.55 1.95e-11 Blood pressure; TGCT cis rs3812831 0.695 rs8000778 chr13:114944310 T/C cg15513719 chr13:114904418 NA 0.36 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs12477438 0.520 rs4588238 chr2:99749350 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs2594989 0.887 rs4684071 chr3:11443084 C/G cg00170343 chr3:11313890 ATG7 0.72 5.35 0.43 4.03e-7 Circulating chemerin levels; TGCT cis rs4727027 0.522 rs6956736 chr7:148893472 G/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.61 4.93 0.4 2.59e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12142240 0.730 rs56030283 chr1:46823093 C/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1801239 1.000 rs79801018 chr10:16937659 T/C cg00939682 chr10:16933505 CUBN 0.48 4.56 0.38 1.23e-5 Urinary albumin-to-creatinine ratio in non-diabetics;Urinary albumin excretion; TGCT cis rs9436747 0.653 rs1751479 chr1:66016205 G/A cg14976592 chr1:65886160 LEPROT;LEPR -0.5 -4.71 -0.39 6.48e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs4499344 0.658 rs10415040 chr19:33052706 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.66 -5.64 -0.45 1.08e-7 Mean platelet volume; TGCT cis rs13191362 0.935 rs67889271 chr6:163045753 T/G cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.5 0.61 5.17e-14 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6909279 0.648 rs6919923 chr6:151849670 T/C cg10883421 chr6:151773342 RMND1;C6orf211 -0.49 -4.44 -0.37 1.95e-5 Bone mineral density; TGCT cis rs208520 1.000 rs208537 chr6:66963544 A/G cg07460842 chr6:66804631 NA -0.83 -7.52 -0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg09060608 chr5:178986726 RUFY1 0.63 7.96 0.58 9.3e-13 Lung cancer; TGCT cis rs7586879 0.616 rs10206196 chr2:25137323 T/C cg15423357 chr2:25149977 NA 0.51 5.06 0.41 1.44e-6 Body mass index; TGCT cis rs6121246 0.909 rs6060960 chr20:30394517 G/T cg13852791 chr20:30311386 BCL2L1 -0.8 -6.26 -0.49 5.77e-9 Mean corpuscular hemoglobin; TGCT cis rs66486766 1 rs66486766 chr15:84806060 G/A cg17173187 chr15:85201210 NMB 0.49 5.13 0.42 1.1e-6 Bipolar disorder lithium response (categorical) or schizophrenia; TGCT cis rs7523050 0.643 rs35662800 chr1:109400816 C/A cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs992157 0.835 rs6729058 chr2:219148369 G/A cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT cis rs9902453 0.933 rs8080343 chr17:28456758 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs709400 0.633 rs8019578 chr14:103977724 A/G cg26031613 chr14:104095156 KLC1 0.86 9.54 0.65 1.61e-16 Body mass index; TGCT cis rs7914558 1.000 rs11191539 chr10:104819770 A/G cg04362960 chr10:104952993 NT5C2 0.61 5.46 0.44 2.44e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs72700829 0.593 rs80350997 chr1:150992010 G/A cg00666978 chr1:150947442 LASS2 0.9 4.62 0.38 9.37e-6 Schizophrenia; TGCT cis rs7829975 0.714 rs11777085 chr8:8672429 G/C cg06636001 chr8:8085503 FLJ10661 0.59 5.25 0.43 6.51e-7 Mood instability; TGCT cis rs732765 0.648 rs8185 chr14:75408789 T/C cg15890469 chr14:75408846 PGF -0.26 -4.64 -0.38 8.68e-6 Non-small cell lung cancer; TGCT cis rs4722166 0.695 rs6946509 chr7:22809490 T/C cg26061582 chr7:22766209 IL6 0.48 6.04 0.48 1.64e-8 Lung cancer; TGCT cis rs2115630 0.755 rs7169629 chr15:85191274 C/G cg11189052 chr15:85197271 WDR73 0.66 6.82 0.52 3.6e-10 P wave terminal force; TGCT cis rs7666738 0.791 rs7657399 chr4:98851861 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6684514 0.961 rs72710222 chr1:156285995 T/C cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs4761974 1.000 rs10876176 chr12:51811832 C/G cg09925572 chr12:51518419 TFCP2 0.47 4.92 0.4 2.69e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs739496 0.579 rs7970847 chr12:112281493 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg23982607 chr1:1823379 GNB1 0.54 8.15 0.59 3.29e-13 Body mass index; TGCT cis rs1372520 0.564 rs2737011 chr4:90746219 T/C cg14346243 chr4:90757452 SNCA -0.6 -4.87 -0.4 3.27e-6 Neuroticism; TGCT cis rs7914558 0.966 rs10786719 chr10:104637992 C/T cg04362960 chr10:104952993 NT5C2 -0.53 -4.7 -0.39 6.9e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2243480 1.000 rs160646 chr7:65556280 C/T cg07424592 chr7:64974309 NA 1.26 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs447735 0.565 rs10852626 chr16:89914633 T/G cg08627397 chr16:89984028 MC1R -0.35 -5.42 -0.44 3.04e-7 Hemoglobin concentration; TGCT cis rs6831352 0.879 rs1230154 chr4:99988659 C/T cg12011299 chr4:100065546 ADH4 0.41 5.06 0.41 1.49e-6 Alcohol dependence; TGCT cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs838147 0.534 rs2638280 chr19:49209318 G/A cg13540341 chr19:49222985 MAMSTR -0.36 -4.76 -0.39 5.33e-6 Dietary macronutrient intake; TGCT cis rs9473924 0.632 rs9473926 chr6:50835815 C/T cg14470998 chr6:50812995 TFAP2B 0.49 4.46 0.37 1.84e-5 Body mass index; TGCT cis rs5167 0.743 rs57204168 chr19:45496776 A/G cg09555818 chr19:45449301 APOC2 0.23 4.93 0.41 2.53e-6 Blood protein levels; TGCT cis rs514406 0.763 rs7535088 chr1:53215042 A/G cg01802117 chr1:53393560 SCP2 0.44 5.26 0.43 6.2e-7 Monocyte count; TGCT cis rs986417 1.000 rs12587609 chr14:60928850 C/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs1059312 0.545 rs12303387 chr12:129276733 C/T cg09035930 chr12:129282057 SLC15A4 -0.51 -7.53 -0.56 9.02e-12 Systemic lupus erythematosus; TGCT cis rs67311347 1.000 rs67680017 chr3:40533164 C/T cg13683864 chr3:40499215 RPL14 -1.16 -10.98 -0.7 5.08e-20 Renal cell carcinoma; TGCT cis rs6089829 0.962 rs7267951 chr20:61665979 A/G cg08045932 chr20:61659980 NA 0.49 9.25 0.64 8.4e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs9952991 0.566 rs11875687 chr18:12843137 T/C cg23598886 chr18:12777645 NA -0.54 -4.73 -0.39 6.11e-6 Inflammatory skin disease; TGCT cis rs4478037 0.558 rs59139633 chr3:33080190 G/T cg19404215 chr3:33155277 CRTAP 1.04 4.95 0.41 2.36e-6 Major depressive disorder; TGCT cis rs709400 0.628 rs3783394 chr14:103858673 G/A cg12935359 chr14:103987150 CKB -0.36 -5.38 -0.43 3.63e-7 Body mass index; TGCT cis rs763014 0.932 rs2384974 chr16:651279 C/G cg27436995 chr16:743998 FBXL16 -0.46 -5.08 -0.42 1.35e-6 Height; TGCT cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs57994353 0.793 rs33982662 chr9:139324737 C/A cg13741927 chr9:139327495 INPP5E -0.27 -6.27 -0.49 5.6e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs12368653 0.666 rs1050045 chr12:58115271 A/G cg12615879 chr12:58013172 SLC26A10 0.47 5.77 0.46 5.9e-8 Multiple sclerosis; TGCT cis rs7698623 0.850 rs7676119 chr4:88780778 G/A cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs875971 0.522 rs4718285 chr7:65292005 A/G cg00343986 chr7:65444356 GUSB 0.26 6.14 0.48 1.02e-8 Aortic root size; TGCT cis rs12681288 0.862 rs4735981 chr8:1018437 A/C cg21347738 chr8:1310380 NA -0.22 -4.55 -0.38 1.26e-5 Schizophrenia; TGCT cis rs7927771 0.832 rs10838697 chr11:47384484 T/A cg21462715 chr11:47870315 NUP160 0.57 4.63 0.38 9.08e-6 Subjective well-being; TGCT cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg10047753 chr17:41438598 NA 0.8 7.34 0.55 2.48e-11 Menopause (age at onset); TGCT cis rs10779751 1.000 rs11121702 chr1:11293147 C/T cg08854313 chr1:11322531 MTOR 0.97 8.94 0.63 4.53e-15 Body mass index; TGCT cis rs1448094 0.556 rs11614513 chr12:86167756 G/C cg02569458 chr12:86230093 RASSF9 0.38 4.49 0.37 1.61e-5 Major depressive disorder; TGCT cis rs3741404 0.609 rs635139 chr11:63872210 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.72 7.39 0.55 1.89e-11 Platelet count; TGCT trans rs208515 0.525 rs10944863 chr6:66676238 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.92 10.09 0.67 7.45e-18 Exhaled nitric oxide levels; TGCT trans rs1005277 0.579 rs1740742 chr10:38518860 C/T cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs9914544 0.689 rs8073236 chr17:18787182 C/G cg26378065 chr17:18585709 ZNF286B 0.52 4.72 0.39 6.3e-6 Educational attainment (years of education); TGCT trans rs57221529 0.608 rs11749927 chr5:668842 C/T cg25482853 chr8:67687455 SGK3 1.13 10.5 0.69 7.9e-19 Lung disease severity in cystic fibrosis; TGCT cis rs4778581 0.864 rs11634397 chr15:80432222 C/T cg00975263 chr15:81073649 KIAA1199 0.24 4.67 0.39 7.77e-6 Reticulocyte count;Reticulocyte fraction of red cells; TGCT cis rs2295359 0.892 rs17375018 chr1:67655147 A/G cg08029281 chr1:67600428 NA -0.42 -4.78 -0.39 4.92e-6 Psoriasis; TGCT cis rs7010267 0.776 rs4407910 chr8:119917117 A/G cg17171407 chr8:119960777 TNFRSF11B -0.28 -4.98 -0.41 2.1e-6 Total body bone mineral density (age 45-60); TGCT cis rs62244186 0.659 rs9819766 chr3:44520980 G/C cg04389838 chr3:44770851 ZNF501 -0.38 -4.94 -0.41 2.45e-6 Depressive symptoms; TGCT cis rs16866061 0.926 rs1523919 chr2:225403615 G/A cg12698349 chr2:225449008 CUL3 0.98 9.17 0.64 1.27e-15 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.88 0.47 3.51e-8 Schizophrenia; TGCT cis rs936229 0.656 rs2290572 chr15:75130573 A/G cg10253484 chr15:75165896 SCAMP2 -0.51 -4.79 -0.4 4.65e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg20276088 chr3:133502917 NA -0.28 -5.95 -0.47 2.51e-8 Iron status biomarkers; TGCT cis rs36022378 0.504 rs4688688 chr3:50042690 C/G cg09562331 chr3:50596116 C3orf18 -0.27 -4.99 -0.41 2e-6 Diastolic blood pressure; TGCT cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg00149659 chr3:10157352 C3orf10 1.05 5.81 0.46 4.95e-8 Alzheimer's disease; TGCT cis rs1008375 0.932 rs10029173 chr4:17659598 C/T cg16339924 chr4:17578868 LAP3 -0.67 -5.48 -0.44 2.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs826838 1.000 rs4768328 chr12:39129315 C/T cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs7220711 1.000 rs7220711 chr17:41789965 C/T cg26893861 chr17:41843967 DUSP3 -0.51 -4.56 -0.38 1.21e-5 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs4077515 0.901 rs34826348 chr9:139281570 A/C cg13741927 chr9:139327495 INPP5E -0.2 -4.69 -0.39 7.19e-6 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs1048238 0.506 rs598371 chr1:16212739 G/A cg22431228 chr1:16359049 CLCNKA 0.22 4.44 0.37 1.93e-5 Systolic blood pressure; TGCT cis rs1055129 0.537 rs2467100 chr17:73949038 C/G cg02678768 chr17:74002944 EVPL 0.24 4.59 0.38 1.06e-5 White matter hyperintensity burden; TGCT cis rs12136530 0.577 rs4912002 chr1:19793402 G/T cg18923740 chr1:19971790 NBL1 0.44 5.45 0.44 2.63e-7 Lead levels in blood; TGCT cis rs7666738 0.830 rs13138059 chr4:99050430 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9486715 1.000 rs6905737 chr6:97066659 A/T cg06623918 chr6:96969491 KIAA0776 -1.08 -13.49 -0.77 4.31e-26 Headache; TGCT cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs4824093 0.610 rs73441745 chr22:50237606 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.07 -6.51 -0.5 1.67e-9 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs17331151 0.573 rs11718060 chr3:52875546 G/A cg07884673 chr3:53033167 SFMBT1 0.5 5.62 0.45 1.19e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7666738 0.830 rs13108705 chr4:99044438 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7010267 0.805 rs6992497 chr8:119980069 A/G cg17171407 chr8:119960777 TNFRSF11B 0.32 6.29 0.49 4.95e-9 Total body bone mineral density (age 45-60); TGCT cis rs3008870 0.958 rs12143044 chr1:67460054 A/T cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs11167764 1.000 rs10057309 chr5:141479870 T/C cg02659431 chr5:141694439 SPRY4 -0.22 -4.76 -0.39 5.36e-6 Crohn's disease; TGCT trans rs7726839 0.540 rs72705030 chr5:645562 C/T cg25482853 chr8:67687455 SGK3 1.2 10.44 0.68 1.1e-18 Obesity-related traits; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg19723775 chr5:179050963 HNRNPH1 -0.52 -5.33 -0.43 4.56e-7 Lung cancer; TGCT cis rs9810089 0.934 rs684195 chr3:135993599 A/C cg12473912 chr3:136751656 NA 0.35 4.9 0.4 2.9e-6 Gestational age at birth (child effect); TGCT cis rs2239547 0.603 rs59989280 chr3:53098875 T/C cg11645453 chr3:52864694 ITIH4 0.3 4.83 0.4 3.88e-6 Schizophrenia; TGCT cis rs7552404 0.727 rs1144336 chr1:76277421 C/A cg03433033 chr1:76189801 ACADM 0.66 6.9 0.53 2.36e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9733 0.596 rs2275236 chr1:150669952 A/G cg04414720 chr1:150670196 GOLPH3L -0.39 -5.04 -0.41 1.58e-6 Tonsillectomy; TGCT cis rs7959452 0.649 rs4761239 chr12:69776886 T/A cg11871910 chr12:69753446 YEATS4 0.85 9.02 0.63 2.92e-15 Blood protein levels; TGCT cis rs6490294 0.904 rs7956483 chr12:112424570 A/G cg10833066 chr12:111807467 FAM109A 0.35 5.13 0.42 1.09e-6 Mean platelet volume; TGCT cis rs9330316 0.591 rs747445 chr2:110352673 G/A cg03552103 chr2:110373002 SEPT10;ANKRD57 -0.39 -4.5 -0.38 1.51e-5 Schizophrenia; TGCT cis rs79387448 0.655 rs75579337 chr2:102917302 C/A cg09003973 chr2:102972529 NA 1.34 8.26 0.6 1.89e-13 Gut microbiota (bacterial taxa); TGCT cis rs6484504 0.512 rs2761594 chr11:31318244 A/G cg26647111 chr11:31128758 NA 0.32 4.64 0.38 8.82e-6 Red blood cell count; TGCT cis rs858239 0.600 rs2072369 chr7:23146189 A/G cg05602783 chr7:23145260 KLHL7 -0.67 -5.68 -0.45 9.25e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs4372836 0.504 rs6760186 chr2:29087274 T/C cg09522027 chr2:28974177 PPP1CB -0.57 -5.63 -0.45 1.14e-7 Body mass index; TGCT cis rs7647973 0.593 rs55997059 chr3:49858661 A/T cg05785598 chr3:49045655 WDR6 -0.42 -5.23 -0.42 7.11e-7 Menarche (age at onset); TGCT cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs4819052 0.808 rs11909411 chr21:46676556 A/C cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7772486 0.875 rs7739371 chr6:146424353 C/G cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6964587 1.000 rs2097739 chr7:91711466 C/T cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs7772486 0.875 rs2748485 chr6:146332421 T/C cg13319975 chr6:146136371 FBXO30 -0.5 -4.48 -0.37 1.67e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs67478160 0.704 rs12894254 chr14:104290949 G/C cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs360798 0.512 rs1420018 chr2:63112500 A/G cg17519650 chr2:63277830 OTX1 0.59 4.93 0.4 2.57e-6 Coronary artery disease; TGCT cis rs10514758 0.744 rs72947718 chr3:114880959 T/G cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs6831352 0.918 rs17218239 chr4:100057020 G/A cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs4273100 0.573 rs4924783 chr17:19253981 A/G cg01534423 chr17:18965556 NA -0.79 -7.62 -0.56 5.53e-12 Schizophrenia; TGCT cis rs9733 0.791 rs11800059 chr1:150651175 C/T cg13175981 chr1:150552382 MCL1 0.43 4.79 0.4 4.64e-6 Tonsillectomy; TGCT cis rs832540 0.931 rs832529 chr5:56229288 C/T cg12311346 chr5:56204834 C5orf35 -0.43 -4.58 -0.38 1.11e-5 Coronary artery disease; TGCT cis rs6669919 0.967 rs894983 chr1:211675279 T/C cg26515805 chr1:211431828 RCOR3 -0.39 -4.62 -0.38 9.32e-6 Intelligence (multi-trait analysis); TGCT cis rs3782455 1.000 rs79001482 chr12:114403542 T/C cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT trans rs1814175 0.781 rs1851872 chr11:50009770 A/G cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs1901167 0.908 rs2876849 chr5:40979790 A/T cg02441090 chr5:41871058 OXCT1 -0.31 -4.61 -0.38 9.86e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs6504950 0.720 rs9910653 chr17:52992268 C/T cg07707039 chr17:53042137 COX11 0.27 4.66 0.39 8.15e-6 Breast cancer; TGCT trans rs916888 0.610 rs199452 chr17:44801340 C/T cg10053473 chr17:62856997 LRRC37A3 -0.4 -6.92 -0.53 2.12e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1538970 0.924 rs1006216 chr1:45909994 A/G cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs514406 0.621 rs1930306 chr1:53195686 C/G cg16325326 chr1:53192061 ZYG11B -0.89 -13.12 -0.76 3.31e-25 Monocyte count; TGCT cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg20302342 chr1:156215951 PAQR6 0.38 5.62 0.45 1.22e-7 Tonsillectomy; TGCT cis rs3015497 0.587 rs1353204 chr14:51081515 C/T cg04730355 chr14:51134070 SAV1 -0.58 -5.41 -0.44 3.15e-7 Mean platelet volume; TGCT cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.59 6.01 0.47 1.92e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs34164013 chr4:98976333 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10804591 1.000 rs729208 chr3:129339642 C/G cg07730360 chr3:128845626 NA 0.2 4.66 0.39 7.91e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11585357 0.843 rs72633805 chr1:17617471 A/T cg08277548 chr1:17600880 PADI3 -0.96 -9.78 -0.66 4.35e-17 Hair shape; TGCT cis rs6665290 0.904 rs11587443 chr1:227187896 T/C cg10327440 chr1:227177885 CDC42BPA -0.99 -20.27 -0.88 3.54e-41 Myeloid white cell count; TGCT cis rs425277 0.628 rs262662 chr1:2085033 A/G cg24578937 chr1:2090814 PRKCZ 0.26 6.95 0.53 1.8e-10 Height; TGCT trans rs3780486 0.834 rs75443249 chr9:33149207 A/G cg20290983 chr6:43655470 MRPS18A 1.12 10.71 0.69 2.41e-19 IgG glycosylation; TGCT cis rs8072100 0.817 rs9892497 chr17:45545919 G/A cg08085267 chr17:45401833 C17orf57 -0.47 -5.14 -0.42 1.05e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1801251 1.000 rs11555646 chr2:233599904 A/C cg25237894 chr2:233734115 C2orf82 0.33 5.94 0.47 2.73e-8 Coronary artery disease; TGCT cis rs9322193 0.923 rs10782317 chr6:150075047 C/T cg13206674 chr6:150067644 NUP43 -0.52 -4.51 -0.38 1.5e-5 Lung cancer; TGCT cis rs7226408 0.802 rs59419623 chr18:34450368 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs4595586 1.000 rs3803020 chr12:39233771 A/G cg10518543 chr12:38710700 ALG10B -0.51 -5.09 -0.42 1.31e-6 Morning vs. evening chronotype; TGCT cis rs11098499 0.863 rs3775848 chr4:120447724 C/T cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs7208859 0.623 rs7503335 chr17:29073962 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7104764 1.000 rs7395328 chr11:242624 T/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs6840360 0.582 rs6535796 chr4:152304728 G/A cg17479576 chr4:152424074 FAM160A1 -0.55 -5.79 -0.46 5.42e-8 Intelligence (multi-trait analysis); TGCT cis rs2895526 0.740 rs7072694 chr10:12692577 G/A cg18283737 chr10:12085149 UPF2 0.46 4.53 0.38 1.38e-5 Headache; TGCT cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg06481639 chr22:41940642 POLR3H 0.69 5.92 0.47 2.95e-8 Vitiligo; TGCT cis rs10771431 0.810 rs10771418 chr12:9358995 A/G cg08997352 chr12:9597637 DDX12 -0.29 -6.11 -0.48 1.2e-8 Breast size; TGCT cis rs7772486 0.875 rs1412081 chr6:146409733 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs57221529 0.709 rs111352378 chr5:577079 G/A cg20362242 chr5:692897 TPPP 0.48 4.51 0.38 1.47e-5 Lung disease severity in cystic fibrosis; TGCT cis rs4689388 0.853 rs13103357 chr4:6294544 A/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4824093 0.535 rs73441802 chr22:50273916 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.13 -6.88 -0.53 2.6e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6967414 0.786 rs6972017 chr7:6754034 A/G cg09896999 chr7:6746977 ZNF12 -0.57 -6.42 -0.5 2.62e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs9325144 0.555 rs1825806 chr12:38692547 G/A cg26384229 chr12:38710491 ALG10B 0.66 6.13 0.48 1.09e-8 Morning vs. evening chronotype; TGCT cis rs12220238 0.915 rs7073139 chr10:76071189 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.28 0.49 5.18e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg21724239 chr8:58056113 NA 0.38 5.18 0.42 8.82e-7 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.609 rs6060983 chr20:30420924 T/C cg18721089 chr20:30220636 NA -0.37 -4.53 -0.38 1.35e-5 Mean corpuscular hemoglobin; TGCT cis rs11679640 0.836 rs17682575 chr2:43152304 C/T cg00705576 chr2:44065259 ABCG5;ABCG8 -0.33 -4.67 -0.39 7.79e-6 White matter hyperintensity burden; TGCT cis rs903263 0.897 rs1472243 chr1:84566165 T/A cg09664975 chr1:84543551 PRKACB 0.49 4.6 0.38 1.01e-5 Breast cancer (male); TGCT cis rs3892630 0.878 rs114224536 chr19:33211232 A/G cg22980127 chr19:33182716 NUDT19 0.71 5.23 0.43 6.93e-7 Red blood cell traits; TGCT cis rs12762955 0.687 rs4880470 chr10:1077480 G/A cg20503657 chr10:835505 NA -0.39 -4.94 -0.41 2.47e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs1552244 0.554 rs28667821 chr3:10050767 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs858239 0.539 rs4377861 chr7:23185969 C/T cg05602783 chr7:23145260 KLHL7 -0.68 -5.62 -0.45 1.2e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.24e-9 Blood metabolite levels; TGCT cis rs11098499 0.866 rs13105020 chr4:120285688 G/T cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs12477438 0.520 rs13022329 chr2:99731189 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs67311347 1.000 rs73080138 chr3:40516417 A/G cg17264618 chr3:40429014 ENTPD3 0.33 4.81 0.4 4.21e-6 Renal cell carcinoma; TGCT cis rs11971779 0.816 rs11979272 chr7:139074069 C/T cg07862535 chr7:139043722 LUC7L2 0.79 5.8 0.46 5.13e-8 Diisocyanate-induced asthma; TGCT cis rs1797081 1.000 rs1797081 chr10:16874565 A/G cg23933602 chr10:16859644 RSU1 1.06 13.37 0.77 8.61e-26 Platelet distribution width; TGCT cis rs2836633 0.929 rs62217519 chr21:40034390 G/A cg05519781 chr21:40033154 ERG 0.7 6.9 0.53 2.36e-10 Coronary artery disease; TGCT cis rs9329221 0.935 rs3750310 chr8:10283426 G/A cg12940923 chr8:10282607 MSRA -0.2 -4.73 -0.39 5.97e-6 Neuroticism; TGCT cis rs2463822 1.000 rs1406384 chr11:62083530 A/G cg23876832 chr11:62092739 NA -0.66 -4.87 -0.4 3.39e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6964587 0.933 rs28671255 chr7:91770705 A/G cg22709100 chr7:91322751 NA 0.28 4.44 0.37 1.96e-5 Breast cancer; TGCT cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg15691649 chr6:25882328 NA -0.4 -4.65 -0.39 8.27e-6 Intelligence (multi-trait analysis); TGCT cis rs854765 0.964 rs854810 chr17:18006421 G/C cg09796270 chr17:17721594 SREBF1 -0.26 -5.22 -0.42 7.3e-7 Total body bone mineral density; TGCT cis rs7208859 0.623 rs9891166 chr17:29111902 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs727505 1.000 rs34986416 chr7:124441017 A/G cg23710748 chr7:124431027 NA -0.27 -4.51 -0.38 1.49e-5 Lewy body disease; TGCT cis rs11716531 0.574 rs13075192 chr3:27279235 C/T cg02860705 chr3:27208620 NA 0.45 7.02 0.53 1.26e-10 Diastolic blood pressure; TGCT cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2456568 0.709 rs1546400 chr11:93639203 G/A cg17595323 chr11:93583763 C11orf90 0.47 6.28 0.49 5.09e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3091242 0.904 rs6661533 chr1:25771715 A/G cg09222892 chr1:25734099 RHCE -0.41 -6.8 -0.52 3.99e-10 Erythrocyte sedimentation rate; TGCT cis rs12497850 0.931 rs13064911 chr3:48952385 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs9985766 1.000 rs28513621 chr4:151002394 G/C cg05926478 chr4:151174724 DCLK2 -0.24 -4.72 -0.39 6.32e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs61990749 0.597 rs6574402 chr14:78267950 C/A cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs796364 0.762 rs13030712 chr2:200973569 G/A cg17644776 chr2:200775616 C2orf69 0.35 6.44 0.5 2.32e-9 Schizophrenia; TGCT cis rs36051895 0.632 rs111573904 chr9:5169804 A/T cg02405213 chr9:5042618 JAK2 -0.7 -8.91 -0.62 5.25e-15 Pediatric autoimmune diseases; TGCT cis rs8180040 0.726 rs13094672 chr3:47149439 C/T cg27129171 chr3:47204927 SETD2 0.73 9.48 0.65 2.25e-16 Colorectal cancer; TGCT cis rs12682352 0.652 rs1567398 chr8:8726804 A/C cg15556689 chr8:8085844 FLJ10661 -0.62 -5.75 -0.46 6.57e-8 Neuroticism; TGCT cis rs4862750 0.957 rs1030381 chr4:187903568 G/C cg22105103 chr4:187893119 NA 0.33 4.76 0.39 5.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3902035 0.894 rs62423969 chr6:119010597 A/G cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs617219 0.698 rs72764988 chr5:78533584 G/C cg23987322 chr5:78407566 BHMT 0.36 4.66 0.39 8.06e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs13191362 0.810 rs34714603 chr6:163008078 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2153535 0.580 rs6597330 chr6:8492076 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs929354 1.000 rs1182413 chr7:157058557 G/A cg05182265 chr7:156933206 UBE3C 0.32 6.64 0.51 8.98e-10 Body mass index; TGCT cis rs1862618 0.756 rs13356762 chr5:56110992 G/T cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs6940638 0.956 rs10946899 chr6:27023694 T/A cg26531700 chr6:26746687 NA -0.54 -4.64 -0.38 8.68e-6 Intelligence (multi-trait analysis); TGCT cis rs7246657 0.550 rs10411176 chr19:37686953 G/T cg24025825 chr19:37761650 NA -0.31 -4.48 -0.37 1.64e-5 Coronary artery calcification; TGCT cis rs36051895 0.554 rs10975027 chr9:5248827 G/A cg02405213 chr9:5042618 JAK2 -0.7 -8.27 -0.6 1.78e-13 Pediatric autoimmune diseases; TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg27535305 chr1:53392650 SCP2 -0.24 -4.69 -0.39 6.96e-6 Monocyte count; TGCT cis rs10540 1.000 rs35068485 chr11:466032 A/T cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs1008375 0.932 rs2302389 chr4:17661889 T/C cg16339924 chr4:17578868 LAP3 0.55 4.62 0.38 9.6e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs523522 0.962 rs4767902 chr12:120910004 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.58 0.51 1.19e-9 High light scatter reticulocyte count; TGCT trans rs1005277 0.579 rs2749612 chr10:38488610 G/A cg17830980 chr10:43048298 ZNF37B -0.84 -10.46 -0.68 9.38e-19 Extrinsic epigenetic age acceleration; TGCT cis rs1670533 0.932 rs13106586 chr4:1054182 G/A cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs4563143 0.647 rs34218744 chr19:29256821 A/T cg14983838 chr19:29218262 NA 0.83 6.76 0.52 4.75e-10 Methadone dose in opioid dependence; TGCT cis rs10875746 0.729 rs1990028 chr12:48408013 A/G cg20731937 chr12:48336164 NA 0.57 4.8 0.4 4.42e-6 Longevity (90 years and older); TGCT cis rs2153535 0.580 rs6912374 chr6:8456423 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs858239 0.600 rs2014768 chr7:23122440 C/A cg05602783 chr7:23145260 KLHL7 -0.64 -5.37 -0.43 3.69e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs7926906 0.967 rs7112148 chr11:90525925 C/G cg26138821 chr11:89956704 CHORDC1 -0.53 -5.7 -0.46 8.12e-8 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs474442 chr11:95583995 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.86 9.04 0.63 2.57e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9915657 0.660 rs975772 chr17:70067810 T/G cg06234051 chr17:70120541 SOX9 -0.25 -5.29 -0.43 5.33e-7 Thyroid hormone levels; TGCT cis rs9916302 0.904 rs11654018 chr17:37703740 C/T cg15445000 chr17:37608096 MED1 -0.32 -4.6 -0.38 1.02e-5 Glomerular filtration rate (creatinine); TGCT cis rs6964587 1.000 rs57816416 chr7:91736078 A/C cg22709100 chr7:91322751 NA 0.29 4.79 0.4 4.67e-6 Breast cancer; TGCT cis rs17102423 0.731 rs61987429 chr14:65606248 C/T cg11161011 chr14:65562177 MAX -0.46 -6.06 -0.48 1.51e-8 Obesity-related traits; TGCT cis rs1215050 0.743 rs6532692 chr4:98648005 C/A cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9814567 0.752 rs4634170 chr3:134335471 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.75 -6.75 -0.52 4.98e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7681440 0.626 rs6812593 chr4:90817991 C/T cg20003494 chr4:90757398 SNCA -0.54 -4.88 -0.4 3.21e-6 Dementia with Lewy bodies; TGCT cis rs4499344 0.664 rs259284 chr19:33163262 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.88 9.49 0.65 2.13e-16 Mean platelet volume; TGCT cis rs9393777 0.778 rs4452638 chr6:27229265 A/G cg10876282 chr6:28092338 ZSCAN16 -0.69 -4.51 -0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.622 rs11637296 chr15:77207885 C/A cg22467129 chr15:76604101 ETFA 0.54 5.4 0.44 3.25e-7 Blood metabolite levels; TGCT cis rs881375 0.967 rs10733648 chr9:123700779 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.38 0.43 3.6e-7 Rheumatoid arthritis; TGCT cis rs6088580 0.634 rs6058070 chr20:33103521 G/C cg08999081 chr20:33150536 PIGU 0.28 5.56 0.45 1.61e-7 Glomerular filtration rate (creatinine); TGCT cis rs9394169 0.592 rs4304152 chr6:33723290 C/T cg13859433 chr6:33739653 LEMD2 -0.32 -5.61 -0.45 1.28e-7 Essential tremor; TGCT cis rs7611238 0.517 rs6437375 chr3:195088100 G/A cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs909002 0.849 rs3753611 chr1:32082486 C/T cg11573219 chr1:32083031 HCRTR1 -0.46 -6.08 -0.48 1.38e-8 Intelligence (multi-trait analysis); TGCT cis rs13082711 0.555 rs73038733 chr3:27263537 C/G cg02860705 chr3:27208620 NA 0.46 7.22 0.54 4.63e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs35160687 0.901 rs12472390 chr2:86475083 T/C cg12542933 chr2:85804724 VAMP8 0.4 4.82 0.4 4.16e-6 Night sleep phenotypes; TGCT cis rs4642101 0.597 rs9839769 chr3:12821405 C/T cg05775895 chr3:12838266 CAND2 0.92 11.11 0.71 2.54e-20 QRS complex (12-leadsum); TGCT cis rs12643440 0.538 rs882315 chr4:17149123 A/T cg22650099 chr4:17144496 NA -0.51 -5.1 -0.42 1.26e-6 Metabolite levels (Pyroglutamine); TGCT cis rs2046867 0.862 rs6805234 chr3:72829869 A/G cg25664220 chr3:72788482 NA -0.53 -6.79 -0.52 4.21e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6683273 0.775 rs12567158 chr1:3226833 A/G cg17435683 chr1:3230609 PRDM16 -0.4 -4.53 -0.38 1.35e-5 QRS duration; TGCT cis rs6867032 1.000 rs2129471 chr5:2016236 C/G cg26168224 chr5:2018326 NA 0.43 7.96 0.58 9.31e-13 Gut microbiome composition (winter); TGCT cis rs4237845 0.636 rs11172371 chr12:58286188 C/T cg23860436 chr12:58378763 NA 0.33 4.49 0.37 1.63e-5 Intelligence (multi-trait analysis); TGCT cis rs2760061 0.598 rs605410 chr1:228116281 A/G cg18477163 chr1:228402036 OBSCN -0.3 -5.94 -0.47 2.71e-8 Diastolic blood pressure; TGCT cis rs9393692 0.905 rs2393592 chr6:26285560 A/G cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.14e-9 Educational attainment; TGCT cis rs12681287 0.517 rs13249753 chr8:87513216 A/G cg27223183 chr8:87520930 FAM82B -0.96 -7.04 -0.53 1.16e-10 Caudate activity during reward; TGCT cis rs13177918 0.677 rs13171800 chr5:149824355 G/A cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs7267979 1.000 rs422424 chr20:25445446 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3087591 0.960 rs4795575 chr17:29452625 A/G cg24425628 chr17:29625626 OMG;NF1 0.47 7.58 0.56 7.13e-12 Hip circumference; TGCT cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg13395646 chr4:1353034 KIAA1530 0.39 4.75 0.39 5.62e-6 Obesity-related traits; TGCT cis rs7119 0.717 rs11639293 chr15:77810845 T/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs265548 0.646 rs36689 chr19:17910639 A/G cg04517722 chr19:17905589 B3GNT3 0.47 6.31 0.49 4.46e-9 Tumor biomarkers; TGCT cis rs9291683 0.530 rs73227883 chr4:9979279 T/C cg11266682 chr4:10021025 SLC2A9 0.63 8.85 0.62 7.35e-15 Bone mineral density; TGCT cis rs9916302 0.706 rs582176 chr17:37453999 T/C cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs2456568 0.867 rs2456569 chr11:93691393 C/A cg16099599 chr11:93583650 C11orf90 -0.39 -4.77 -0.39 5.16e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs12216125 0.549 rs9358905 chr6:26077839 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.38 0.55 2.03e-11 Iron status biomarkers; TGCT cis rs2334880 0.678 rs7186112 chr16:71840073 A/T cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Malaria; TGCT cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg02458000 chr6:26745757 NA -0.5 -4.55 -0.38 1.24e-5 Schizophrenia; TGCT cis rs7193541 0.929 rs12933037 chr16:74660174 G/A cg05800356 chr16:74706258 MLKL 0.25 4.53 0.38 1.38e-5 Multiple myeloma; TGCT cis rs7726839 0.574 rs12522955 chr5:639231 C/A cg09021430 chr5:549028 NA -0.38 -5.11 -0.42 1.21e-6 Obesity-related traits; TGCT cis rs7660520 0.556 rs4862103 chr4:183735309 G/A cg04181038 chr4:183730758 NA 0.66 6.03 0.48 1.78e-8 Pediatric autoimmune diseases; TGCT cis rs13108904 0.967 rs2293635 chr4:1291791 A/G cg00684032 chr4:1343700 KIAA1530 0.23 5.01 0.41 1.79e-6 Obesity-related traits; TGCT cis rs9894429 0.816 rs9747093 chr17:79584280 G/A cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs7178572 0.568 rs12901297 chr15:77386675 G/A cg22256960 chr15:77711686 NA -0.84 -8.32 -0.6 1.34e-13 Type 2 diabetes; TGCT cis rs362296 0.698 rs3095082 chr4:3263617 C/A cg06533319 chr4:3265114 C4orf44 0.23 4.64 0.38 8.9e-6 Parental longevity (mother's age at death); TGCT cis rs40363 0.645 rs250631 chr16:3523215 G/C cg21433313 chr16:3507492 NAT15 0.38 5.03 0.41 1.71e-6 Tuberculosis; TGCT cis rs56104184 0.830 rs45589039 chr19:49355385 C/T cg17863274 chr19:49399704 TULP2 -0.5 -6.03 -0.48 1.76e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2688608 0.967 rs2633299 chr10:75656754 T/G cg19442545 chr10:75533431 FUT11 -0.29 -4.71 -0.39 6.5e-6 Inflammatory bowel disease; TGCT cis rs13256369 1.000 rs12550458 chr8:8567832 G/A cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs10089 1.000 rs10478798 chr5:127442394 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.43 0.56 1.53e-11 Ileal carcinoids; TGCT cis rs4788439 0.901 rs74013609 chr16:24995421 C/A cg07626409 chr16:25250191 ZKSCAN2 0.32 4.45 0.37 1.87e-5 Blood metabolite levels; TGCT cis rs7178572 0.962 rs12324627 chr15:77767539 A/G cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs9486719 0.895 rs12527021 chr6:97025496 C/T cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs7772486 0.727 rs12190966 chr6:146146820 T/G cg05347473 chr6:146136440 FBXO30 0.5 4.72 0.39 6.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6121246 0.567 rs6060262 chr20:30193071 A/C cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.42e-6 Mean corpuscular hemoglobin; TGCT cis rs12220238 1.000 rs7904207 chr10:75884474 A/T cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.78 -8.0 -0.58 7.45e-13 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs9380058 chr6:28127444 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7666738 0.830 rs10022389 chr4:99022229 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs1385374 0.563 rs12299194 chr12:129264838 A/G cg09035930 chr12:129282057 SLC15A4 -0.54 -4.76 -0.39 5.33e-6 Systemic lupus erythematosus; TGCT cis rs6977660 0.507 rs28402966 chr7:19774469 A/C cg07541023 chr7:19748670 TWISTNB 1.01 6.55 0.51 1.39e-9 Thyroid stimulating hormone; TGCT trans rs564343 0.545 rs576836 chr11:65823569 G/C cg26701943 chr11:108369231 KDELC2 -0.74 -6.92 -0.53 2.11e-10 Obesity (early onset extreme); TGCT cis rs9788721 0.836 rs72738732 chr15:78752188 C/G cg18825076 chr15:78729989 IREB2 -0.34 -5.11 -0.42 1.18e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg03806693 chr22:41940476 POLR3H 1.12 12.44 0.75 1.45e-23 Vitiligo; TGCT cis rs6671200 1.000 rs259359 chr1:95709039 A/G cg20701556 chr1:95698924 RWDD3 -0.65 -5.55 -0.45 1.67e-7 Stearic acid (18:0) levels; TGCT cis rs7959452 0.901 rs1384 chr12:69747834 C/T cg20891283 chr12:69753455 YEATS4 0.69 6.81 0.52 3.67e-10 Blood protein levels; TGCT cis rs9393692 0.905 rs1124999 chr6:26287043 G/T cg13736514 chr6:26305472 NA -0.41 -5.76 -0.46 6.12e-8 Educational attainment; TGCT cis rs17253792 0.822 rs112418863 chr14:56114079 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs17376456 0.877 rs7701974 chr5:93311417 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT trans rs61931739 0.500 rs35391785 chr12:34444478 C/T cg26384229 chr12:38710491 ALG10B 0.73 6.93 0.53 2e-10 Morning vs. evening chronotype; TGCT trans rs114540395 0.858 rs75919232 chr10:103289312 A/G cg10198749 chr1:39920707 MACF1 0.55 7.05 0.53 1.11e-10 Schizophrenia; TGCT cis rs11098499 0.863 rs6833334 chr4:120504227 C/T cg09307838 chr4:120376055 NA 0.68 6.47 0.5 2.02e-9 Corneal astigmatism; TGCT cis rs7208859 0.615 rs216462 chr17:28895897 T/C cg14008862 chr17:28927542 LRRC37B2 -0.77 -4.47 -0.37 1.78e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1799949 1.000 rs8176265 chr17:41213996 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 4.92 0.4 2.75e-6 Menopause (age at onset); TGCT cis rs55883249 0.957 rs62119393 chr2:9718247 C/T cg23886495 chr2:9695866 ADAM17 0.79 4.71 0.39 6.49e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs478304 0.654 rs11601509 chr11:65456864 T/C cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.79e-13 Acne (severe); TGCT trans rs3107575 0.572 rs73169366 chr3:165320307 C/T cg20820622 chr15:70354647 TLE3 0.97 6.63 0.51 9.3e-10 Morning vs. evening chronotype; TGCT cis rs9467711 0.516 rs1165184 chr6:25836257 C/G cg16898833 chr6:26189333 HIST1H4D 0.7 4.45 0.37 1.9e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs72945132 0.882 rs7122057 chr11:70201430 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7095607 0.813 rs7911060 chr10:69929058 T/C cg18986048 chr10:69913749 MYPN 0.46 5.24 0.43 6.63e-7 Lung function (FVC); TGCT cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg12667521 chr19:29218732 NA 0.55 5.9 0.47 3.29e-8 Methadone dose in opioid dependence; TGCT cis rs832540 0.931 rs832399 chr5:56222358 A/T cg12311346 chr5:56204834 C5orf35 -0.48 -5.18 -0.42 8.6e-7 Coronary artery disease; TGCT cis rs9291768 0.967 rs10939961 chr5:50738478 A/C cg24549912 chr5:50692281 NA -0.22 -4.47 -0.37 1.72e-5 Classic bladder exstrophy; TGCT cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.875 rs1929523 chr6:146339989 T/A cg23711669 chr6:146136114 FBXO30 0.88 9.67 0.66 7.78e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7258465 1.000 rs10425982 chr19:18586519 T/A cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs9486719 1.000 rs10457159 chr6:96993139 G/A cg18709589 chr6:96969512 KIAA0776 -0.76 -5.32 -0.43 4.63e-7 Migraine;Coronary artery disease; TGCT cis rs6688613 0.765 rs56229522 chr1:166816108 T/A cg07049167 chr1:166818506 POGK 0.21 4.55 0.38 1.26e-5 Refractive astigmatism; TGCT cis rs7089973 0.604 rs2420069 chr10:116605103 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7829975 0.902 rs485107 chr8:8581408 C/G cg06636001 chr8:8085503 FLJ10661 -0.59 -4.91 -0.4 2.78e-6 Mood instability; TGCT cis rs2439831 1.000 rs689781 chr15:43792097 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.51 0.44 1.95e-7 Lung cancer in ever smokers; TGCT cis rs9399137 0.507 rs13196486 chr6:135283874 C/G cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs9486719 1.000 rs1303852 chr6:96864523 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT trans rs1814175 0.645 rs1721997 chr11:49916653 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs7760949 0.889 rs9396264 chr6:13930342 T/A cg27413430 chr6:13925136 RNF182 0.73 6.79 0.52 4.22e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7917772 0.636 rs7088981 chr10:104520423 T/C cg05855489 chr10:104503620 C10orf26 0.66 5.25 0.43 6.47e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2797160 0.967 rs1777224 chr6:126019527 T/C cg05901451 chr6:126070800 HEY2 0.71 6.11 0.48 1.16e-8 Endometrial cancer; TGCT cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg21724239 chr8:58056113 NA 0.39 5.24 0.43 6.67e-7 Developmental language disorder (linguistic errors); TGCT cis rs6087990 0.842 rs6119279 chr20:31330612 A/G cg13636640 chr20:31349939 DNMT3B 1.03 14.85 0.8 2.67e-29 Ulcerative colitis; TGCT cis rs3026101 0.697 rs1806267 chr17:5322106 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.76 0.39 5.25e-6 Body mass index; TGCT cis rs7666738 0.830 rs6831588 chr4:98977356 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs986417 0.901 rs1950312 chr14:60989784 A/G cg27398547 chr14:60952738 C14orf39 -1.47 -10.59 -0.69 4.68e-19 Gut microbiota (bacterial taxa); TGCT cis rs3806843 0.607 rs246044 chr5:140330656 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.42 -5.37 -0.43 3.69e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg06634786 chr22:41940651 POLR3H -0.88 -8.23 -0.59 2.17e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3733585 0.781 rs13103690 chr4:9972778 T/G cg11266682 chr4:10021025 SLC2A9 -0.62 -8.54 -0.61 4.06e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs362272 0.545 rs2749783 chr4:3326098 A/C cg18352616 chr4:3374830 RGS12 0.25 5.07 0.41 1.39e-6 Serum sulfate level; TGCT cis rs250677 1.000 rs36082 chr5:148428844 C/G cg23229984 chr5:148520753 ABLIM3 0.21 4.95 0.41 2.33e-6 Breast cancer; TGCT cis rs35522438 1 rs35522438 chr7:91872872 A/AT cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.2e-5 Breast cancer; TGCT cis rs9303542 0.625 rs17703660 chr17:46567134 T/C cg25032089 chr17:46643351 HOXB3 0.58 5.96 0.47 2.45e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg07507251 chr3:52567010 NT5DC2 0.48 6.67 0.51 7.55e-10 Bipolar disorder; TGCT cis rs11971779 0.680 rs11768023 chr7:139054395 T/A cg07862535 chr7:139043722 LUC7L2 0.66 5.07 0.41 1.42e-6 Diisocyanate-induced asthma; TGCT cis rs910316 1.000 rs4903281 chr14:75554361 G/C cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs6430585 0.591 rs4585083 chr2:136486342 C/T cg07169764 chr2:136633963 MCM6 1.12 10.49 0.69 8.04e-19 Corneal structure; TGCT cis rs6952808 0.624 rs60137119 chr7:2083664 A/G cg04267008 chr7:1944627 MAD1L1 -0.41 -5.51 -0.44 1.96e-7 Bipolar disorder and schizophrenia; TGCT cis rs7568458 0.846 rs6738645 chr2:85783128 T/G cg17127132 chr2:85788382 GGCX 0.68 6.58 0.51 1.2e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1371867 0.846 rs1660338 chr8:101242757 C/G cg06002616 chr8:101225028 SPAG1 -0.52 -6.2 -0.49 7.79e-9 Atrioventricular conduction; TGCT cis rs10883723 0.810 rs2296581 chr10:104242886 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs854765 0.547 rs2955359 chr17:17946730 T/C cg04398451 chr17:18023971 MYO15A 0.34 5.49 0.44 2.21e-7 Total body bone mineral density; TGCT cis rs5417 0.636 rs222851 chr17:7139238 G/A cg25256661 chr17:7137939 DVL2 0.68 6.66 0.51 7.88e-10 Diastolic blood pressure; TGCT cis rs3796352 1.000 rs3796352 chr3:52913279 C/T cg07884673 chr3:53033167 SFMBT1 0.6 4.88 0.4 3.16e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg07157834 chr1:205819609 PM20D1 0.49 8.67 0.61 2.01e-14 Menarche (age at onset); TGCT cis rs2832191 0.935 rs67287920 chr21:30523519 C/A cg24692254 chr21:30365293 RNF160 -0.8 -8.31 -0.6 1.41e-13 Dental caries; TGCT cis rs12257961 0.549 rs56276505 chr10:15382499 G/A cg10616319 chr10:15468812 NA 0.25 4.71 0.39 6.49e-6 Selective IgA deficiency; TGCT cis rs7172809 0.897 rs907387 chr15:77828751 T/C cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs3733606 0.503 rs11734132 chr4:6891519 C/G cg27326882 chr4:7789542 AFAP1 -0.26 -5.11 -0.42 1.19e-6 Platelet count; TGCT cis rs67478160 0.608 rs11628787 chr14:104323984 G/A cg01849466 chr14:104193079 ZFYVE21 0.18 4.5 0.37 1.54e-5 Schizophrenia; TGCT cis rs9902453 0.967 rs62070344 chr17:28476997 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.56 0.51 1.32e-9 Coffee consumption (cups per day); TGCT cis rs1894292 0.527 rs2040354 chr4:74367100 C/T cg05868023 chr4:75230803 EREG -0.56 -5.02 -0.41 1.78e-6 Prostate cancer; TGCT cis rs896854 0.738 rs2515226 chr8:95965743 G/A cg16049864 chr8:95962084 TP53INP1 0.64 7.66 0.57 4.51e-12 Type 2 diabetes; TGCT cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg17264618 chr3:40429014 ENTPD3 0.35 5.09 0.42 1.27e-6 Renal cell carcinoma; TGCT cis rs10193935 0.901 rs10189710 chr2:42573102 C/G cg27598129 chr2:42591480 NA -0.4 -5.57 -0.45 1.51e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1023500 0.551 rs4822076 chr22:42364057 C/T cg05082376 chr22:42548792 NA -0.22 -4.86 -0.4 3.53e-6 Schizophrenia; TGCT cis rs55883249 1.000 rs62119429 chr2:9743585 G/C cg23886495 chr2:9695866 ADAM17 0.81 5.0 0.41 1.93e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs2072438 0.503 rs10739590 chr9:123871481 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.48 0.37 1.65e-5 Rheumatoid arthritis; TGCT cis rs2404602 0.692 rs59088060 chr15:76859974 T/C cg26408565 chr15:76604113 ETFA -0.37 -4.78 -0.39 4.9e-6 Blood metabolite levels; TGCT cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7677751 0.806 rs4864858 chr4:55089953 T/A cg17187183 chr4:55093834 PDGFRA 0.53 6.87 0.52 2.83e-10 Corneal astigmatism; TGCT cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.12 15.23 0.81 3.53e-30 Height; TGCT cis rs78487399 0.908 rs61271889 chr2:43825436 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs208520 0.690 rs1351867 chr6:66760995 A/G cg07460842 chr6:66804631 NA 0.96 10.32 0.68 2.1e-18 Exhaled nitric oxide output; TGCT cis rs7399018 0.739 rs7399073 chr12:51614050 C/A cg25754956 chr12:51612065 POU6F1 0.92 9.95 0.67 1.64e-17 Cisplatin-induced ototoxicity; TGCT cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs2948294 0.524 rs13270062 chr8:8112650 C/A cg15556689 chr8:8085844 FLJ10661 0.78 6.78 0.52 4.31e-10 Red cell distribution width; TGCT cis rs295137 0.752 rs10931892 chr2:201104997 C/T cg23649088 chr2:200775458 C2orf69 -0.34 -5.82 -0.46 4.79e-8 Asthma (bronchodilator response); TGCT cis rs1799949 0.965 rs7212284 chr17:41205941 A/G cg05368731 chr17:41323189 NBR1 0.95 9.3 0.64 6.14e-16 Menopause (age at onset); TGCT cis rs2115630 0.967 rs8028490 chr15:85277888 G/A cg11189052 chr15:85197271 WDR73 -0.62 -6.0 -0.47 2e-8 P wave terminal force; TGCT cis rs9400467 0.537 rs12213673 chr6:111544839 C/T cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs9372498 0.536 rs9489399 chr6:118767147 C/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs2982552 0.775 rs2982563 chr6:152052311 T/C cg22157087 chr6:152012887 ESR1 0.19 4.67 0.39 7.81e-6 Bone properties (heel); TGCT cis rs858239 0.600 rs1468592 chr7:23140647 C/T cg05602783 chr7:23145260 KLHL7 0.64 5.35 0.43 4.15e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs1862618 0.802 rs33327 chr5:56142693 T/G cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs77633900 0.614 rs2468123 chr15:76931345 T/C cg21673338 chr15:77095150 SCAPER -0.5 -4.82 -0.4 4.07e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg22166914 chr1:53195759 ZYG11B 0.35 5.78 0.46 5.7e-8 Monocyte count; TGCT cis rs6088580 0.609 rs6059844 chr20:33036482 A/G cg08999081 chr20:33150536 PIGU 0.28 5.7 0.46 8.38e-8 Glomerular filtration rate (creatinine); TGCT cis rs7086627 0.515 rs10887905 chr10:82210855 A/T cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs9393777 0.513 rs7759969 chr6:26663096 T/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs1348850 0.668 rs6734426 chr2:178493770 C/T cg22681709 chr2:178499509 PDE11A -0.43 -4.48 -0.37 1.65e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs8141529 0.732 rs11556025 chr22:29168755 T/C cg02153584 chr22:29168773 CCDC117 0.7 6.01 0.47 1.92e-8 Lymphocyte counts; TGCT cis rs6993813 0.505 rs35533151 chr8:120023725 T/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Bone mineral density (hip); TGCT cis rs2354432 1.000 rs2120003 chr1:146690635 A/G cg25205988 chr1:146714368 CHD1L 1.17 5.89 0.47 3.38e-8 Mitochondrial DNA levels; TGCT cis rs909685 0.590 rs3747177 chr22:39746168 C/A cg17798944 chr22:39715225 SNORD43;RPL3 0.79 7.3 0.55 3.03e-11 Rheumatoid arthritis; TGCT cis rs709400 0.659 rs7160366 chr14:103944137 C/T cg26031613 chr14:104095156 KLC1 0.85 9.72 0.66 5.87e-17 Body mass index; TGCT cis rs9517302 0.615 rs2274053 chr13:99098318 C/T cg22223119 chr13:99095684 FARP1 -0.65 -7.18 -0.54 5.7e-11 Obesity-related traits; TGCT cis rs1696756 0.877 rs1663223 chr17:77826509 A/G cg00646381 chr17:77835854 NA 0.42 5.94 0.47 2.71e-8 Glucocorticoid-induced osteonecrosis (age 10 years and older); TGCT cis rs2820315 1.000 rs2678204 chr1:201800511 T/G cg12730843 chr1:201915899 LMOD1 -0.27 -4.81 -0.4 4.22e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs4975709 0.589 rs1466607 chr5:1864856 A/G cg14773178 chr5:1868261 NA 0.35 6.19 0.49 7.93e-9 Cardiovascular disease risk factors; TGCT cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg11494091 chr17:61959527 GH2 0.42 7.28 0.55 3.36e-11 Height; TGCT cis rs2235642 0.653 rs7197288 chr16:1654753 C/A cg08296037 chr16:1584118 IFT140;TMEM204 -0.28 -4.94 -0.41 2.44e-6 Coronary artery disease; TGCT cis rs7666738 0.791 rs6853608 chr4:99047916 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT trans rs1005277 0.579 rs2474563 chr10:38375938 T/C cg17830980 chr10:43048298 ZNF37B -0.87 -11.04 -0.7 3.63e-20 Extrinsic epigenetic age acceleration; TGCT cis rs17774123 0.671 rs3843640 chr12:54263812 G/T cg14212748 chr12:53343703 KRT18 -0.38 -4.65 -0.39 8.31e-6 Diastolic blood pressure; TGCT cis rs4824093 0.610 rs56810176 chr22:50303149 G/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.07 -5.93 -0.47 2.87e-8 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2290402 0.536 rs73207791 chr4:865941 A/G cg23332689 chr4:987652 IDUA;SLC26A1 0.31 4.82 0.4 4.12e-6 Type 2 diabetes; TGCT cis rs514406 0.861 rs503296 chr1:53283088 A/G cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs259282 0.518 rs259257 chr19:33152296 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 1.01 10.27 0.68 2.83e-18 Schizophrenia; TGCT cis rs7954584 0.531 rs11043271 chr12:122394921 A/C cg21016266 chr12:122356598 WDR66 0.53 6.62 0.51 9.94e-10 Mean corpuscular volume; TGCT cis rs875971 1.000 rs778685 chr7:65836176 G/T cg11764359 chr7:65958608 NA 0.62 5.57 0.45 1.51e-7 Aortic root size; TGCT cis rs6840360 0.571 rs62327271 chr4:152535916 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs6671200 1.000 rs62625008 chr1:95702582 A/G cg20701556 chr1:95698924 RWDD3 0.67 5.63 0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs7845219 0.525 rs7820818 chr8:95919231 G/A cg13393036 chr8:95962371 TP53INP1 -0.49 -5.49 -0.44 2.2e-7 Type 2 diabetes; TGCT cis rs2299587 0.554 rs2073564 chr8:17743341 G/A cg01800426 chr8:17659068 MTUS1 -0.55 -4.96 -0.41 2.25e-6 Economic and political preferences; TGCT cis rs1055129 0.560 rs9891076 chr17:73911715 C/T cg10935138 chr17:73851978 WBP2 0.54 4.71 0.39 6.58e-6 White matter hyperintensity burden; TGCT cis rs2580764 0.541 rs2968786 chr2:55264859 C/G cg09592903 chr2:55203963 RTN4 0.27 6.17 0.48 8.73e-9 Mean platelet volume; TGCT cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg19318889 chr4:1322082 MAEA 0.28 6.7 0.52 6.39e-10 Longevity; TGCT cis rs1971762 0.583 rs12319789 chr12:54090450 G/C cg16917193 chr12:54089295 NA 1.34 17.67 0.85 1.12e-35 Height; TGCT cis rs74233809 1.000 rs11191531 chr10:104806898 G/C cg05855489 chr10:104503620 C10orf26 0.76 4.53 0.38 1.36e-5 Birth weight; TGCT cis rs597539 0.652 rs569777 chr11:68706848 G/A cg21862992 chr11:68658383 NA 0.46 6.26 0.49 5.67e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3087591 0.920 rs4795592 chr17:29612620 C/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.37 -0.55 2.08e-11 Hip circumference; TGCT cis rs7267979 1.000 rs2387880 chr20:25377787 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7635838 0.785 rs2574698 chr3:11557126 G/A cg00170343 chr3:11313890 ATG7 0.68 6.16 0.48 9.56e-9 HDL cholesterol; TGCT cis rs1577917 0.958 rs1447160 chr6:86546123 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs941408 1.000 rs1736180 chr19:2796021 C/T cg06609049 chr19:2785107 THOP1 0.76 7.24 0.54 4.22e-11 Total cholesterol levels; TGCT cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6545883 0.899 rs1562309 chr2:61770126 C/A cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs5769707 0.521 rs6009807 chr22:50058922 A/G cg05373962 chr22:49881684 NA -0.32 -5.46 -0.44 2.46e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs3806843 0.548 rs246058 chr5:140325134 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg20607798 chr8:58055168 NA 0.65 5.5 0.44 2.08e-7 Developmental language disorder (linguistic errors); TGCT cis rs950027 0.549 rs12909409 chr15:45608582 T/G cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.89 -0.47 3.46e-8 Response to fenofibrate (adiponectin levels); TGCT trans rs17685 0.753 rs10245584 chr7:75745866 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7666738 0.861 rs10018654 chr4:99002226 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7617773 0.780 rs11716848 chr3:48378500 G/A cg11946769 chr3:48343235 NME6 0.82 6.99 0.53 1.49e-10 Coronary artery disease; TGCT cis rs9677476 0.515 rs2303353 chr2:231944373 A/T cg27665808 chr2:232055229 NA 0.37 4.68 0.39 7.25e-6 Food antigen IgG levels; TGCT trans rs1814175 0.616 rs28417656 chr11:50040152 C/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs2153535 0.580 rs9392224 chr6:8472614 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9952991 0.941 rs2542151 chr18:12779947 G/T cg24737193 chr18:12778029 NA 0.53 6.01 0.47 1.96e-8 Inflammatory skin disease; TGCT cis rs7429990 0.965 rs34507589 chr3:47874042 C/G cg11946769 chr3:48343235 NME6 0.59 4.45 0.37 1.87e-5 Educational attainment (years of education); TGCT cis rs4722166 0.597 rs2002792 chr7:22763845 C/G cg23864514 chr7:22882512 NA 0.21 4.6 0.38 1.03e-5 Lung cancer; TGCT cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs8017423 0.967 rs2282030 chr14:90730265 G/A cg04374321 chr14:90722782 PSMC1 0.78 7.86 0.58 1.63e-12 Mortality in heart failure; TGCT cis rs6570726 0.791 rs374478 chr6:145840022 C/T cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg04025307 chr7:1156635 C7orf50 0.21 5.13 0.42 1.1e-6 Longevity;Endometriosis; TGCT cis rs11032090 1 rs11032090 chr11:4417129 A/G cg09983885 chr11:4415245 TRIM21 0.39 4.67 0.39 7.63e-6 Lung cancer; TGCT cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg03264133 chr6:25882463 NA -0.64 -6.81 -0.52 3.66e-10 Blood metabolite levels; TGCT cis rs55883249 1.000 rs76964971 chr2:9763904 C/A cg23886495 chr2:9695866 ADAM17 0.74 4.45 0.37 1.9e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs594074 0.859 rs570251 chr6:6556378 C/A cg03251356 chr6:7151709 RREB1 0.31 4.68 0.39 7.38e-6 Diabetic kidney disease; TGCT cis rs2836974 0.899 rs6517514 chr21:40527095 G/T cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs858239 0.600 rs7785842 chr7:23141706 T/A cg05602783 chr7:23145260 KLHL7 -0.68 -5.75 -0.46 6.69e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs4455778 0.580 rs5004391 chr7:49115629 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs939658 0.935 rs4778651 chr15:79447810 G/A cg17916960 chr15:79447300 NA -0.52 -8.3 -0.6 1.5e-13 Refractive error; TGCT trans rs1005277 0.579 rs2504148 chr10:38400788 A/G cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg08280861 chr8:58055591 NA -0.38 -4.56 -0.38 1.19e-5 Developmental language disorder (linguistic errors); TGCT cis rs6500602 0.826 rs7205189 chr16:4460114 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 5.27 0.43 5.92e-7 Schizophrenia; TGCT cis rs7818688 0.697 rs78802294 chr8:95977974 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 6.94 0.53 1.91e-10 Prudent dietary pattern; TGCT cis rs2456568 0.803 rs10831142 chr11:93640781 A/G cg17595323 chr11:93583763 C11orf90 0.47 6.56 0.51 1.34e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7833790 0.660 rs67666182 chr8:82772037 A/G cg06027949 chr8:82754900 SNX16 0.67 5.14 0.42 1.06e-6 Diastolic blood pressure; TGCT cis rs9457247 0.534 rs2757053 chr6:167380338 A/C cg23791538 chr6:167370224 RNASET2 0.63 6.24 0.49 6.21e-9 Crohn's disease; TGCT cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg11062466 chr8:58055876 NA 0.43 6.3 0.49 4.61e-9 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.520 rs2516830 chr2:99773702 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs12438659 1 rs12438659 chr15:78824924 G/A cg06917634 chr15:78832804 PSMA4 -0.7 -5.01 -0.41 1.83e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7914558 0.966 rs746293 chr10:104897254 G/T cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.66e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6860806 0.695 rs6867282 chr5:131583120 G/C cg24060327 chr5:131705240 SLC22A5 -0.58 -5.91 -0.47 3.13e-8 Breast cancer; TGCT cis rs4499344 0.920 rs752719 chr19:33086091 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.6 -0.51 1.07e-9 Mean platelet volume; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs6933660 0.720 rs6913515 chr6:151753470 G/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.86 -9.14 -0.63 1.49e-15 Menarche (age at onset); TGCT cis rs7226408 0.857 rs72887051 chr18:34486993 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7308134 0.766 rs73032452 chr12:1990683 C/T cg09189752 chr12:2113749 DCP1B -0.57 -4.44 -0.37 1.93e-5 QRS duration in Tripanosoma cruzi seropositivity; TGCT cis rs17376456 0.877 rs9314095 chr5:93425495 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs62103177 0.525 rs4799117 chr18:77756604 G/A cg07235805 chr18:78004237 PARD6G -0.45 -4.47 -0.37 1.75e-5 Opioid sensitivity; TGCT cis rs7208859 0.673 rs73265633 chr17:29236306 G/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1799949 1.000 rs11653253 chr17:41182662 G/A cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs72615157 0.645 rs76281814 chr7:99846414 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.82 0.4 4.1e-6 Lung function (FEV1/FVC); TGCT cis rs514406 0.861 rs35581164 chr1:53271373 C/G cg16325326 chr1:53192061 ZYG11B 0.7 8.67 0.61 2.03e-14 Monocyte count; TGCT cis rs35306767 0.903 rs35370435 chr10:898205 T/C cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs7208859 0.573 rs73267873 chr17:29068457 C/T cg13385521 chr17:29058706 SUZ12P 0.82 5.04 0.41 1.61e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7937682 0.924 rs513425 chr11:111504861 C/T cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs79349575 0.783 rs12601955 chr17:47034420 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.48 -0.37 1.67e-5 Type 2 diabetes; TGCT cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg21280719 chr6:42927975 GNMT -0.37 -4.5 -0.37 1.55e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9905704 0.671 rs4337355 chr17:56950920 C/T cg05425664 chr17:57184151 TRIM37 -0.59 -4.69 -0.39 7.16e-6 Testicular germ cell tumor; TGCT cis rs7666738 0.830 rs28615340 chr4:98896922 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.81 0.4 4.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7824557 0.510 rs1435274 chr8:11235910 G/A cg21775007 chr8:11205619 TDH -0.67 -6.51 -0.5 1.7e-9 Retinal vascular caliber; TGCT cis rs12681288 0.676 rs7459467 chr8:999359 C/T cg04851639 chr8:1020857 NA -0.32 -5.32 -0.43 4.74e-7 Schizophrenia; TGCT cis rs2721195 0.845 rs3816732 chr8:145724275 T/C cg11211951 chr8:145729740 GPT 0.27 6.46 0.5 2.14e-9 Age at first birth; TGCT cis rs12681288 0.723 rs12545453 chr8:970582 C/T cg04851639 chr8:1020857 NA -0.33 -5.54 -0.45 1.74e-7 Schizophrenia; TGCT cis rs9914544 1.000 rs1634411 chr17:18833810 C/T cg26306683 chr17:18585705 ZNF286B 0.59 5.26 0.43 5.99e-7 Educational attainment (years of education); TGCT cis rs858239 0.539 rs28716381 chr7:23189015 G/A cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2797160 0.967 rs1739358 chr6:126019736 G/A cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 4.85e-9 Endometrial cancer; TGCT cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs7635838 0.596 rs347599 chr3:11258191 C/T cg00170343 chr3:11313890 ATG7 -0.51 -4.92 -0.4 2.65e-6 HDL cholesterol; TGCT cis rs7100689 0.646 rs1890889 chr10:82090827 G/T cg01528321 chr10:82214614 TSPAN14 0.76 7.53 0.56 9.05e-12 Post bronchodilator FEV1; TGCT cis rs7659604 0.539 rs3217771 chr4:122739483 G/A cg19748678 chr4:122722346 EXOSC9 0.9 9.35 0.64 4.81e-16 Type 2 diabetes; TGCT cis rs4819052 0.851 rs7276591 chr21:46680156 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs904251 0.561 rs1757189 chr6:37483727 G/C cg08126542 chr6:37504118 NA -0.43 -6.2 -0.49 7.72e-9 Cognitive performance; TGCT cis rs1385374 0.858 rs34888374 chr12:129296536 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs9611519 0.580 rs7286603 chr22:41440061 T/C cg13695892 chr22:41940480 POLR3H -0.56 -5.29 -0.43 5.29e-7 Neuroticism; TGCT cis rs7267979 0.932 rs372678 chr20:25465248 G/A cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11642862 1.000 rs75231191 chr16:30788601 C/T cg02466173 chr16:30829666 NA -0.38 -4.57 -0.38 1.16e-5 Tonsillectomy; TGCT cis rs2456568 0.695 rs877341 chr11:93689293 C/T cg17595323 chr11:93583763 C11orf90 0.4 4.99 0.41 1.98e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10193935 1.000 rs13399869 chr2:42386041 C/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3784262 1.000 rs12907038 chr15:58244032 C/G cg12031962 chr15:58353849 ALDH1A2 -0.48 -7.39 -0.55 1.9e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs151227923 1 rs151227923 chr7:155106564 C/T cg06963709 chr7:155150793 NA 0.35 6.84 0.52 3.2e-10 Stem cell growth factor beta levels; TGCT trans rs629535 0.821 rs680993 chr8:70050247 G/A cg21567404 chr3:27674614 NA 0.57 8.67 0.61 2.01e-14 Dupuytren's disease; TGCT cis rs9581857 0.685 rs12584061 chr13:28024544 C/T cg22138327 chr13:27999177 GTF3A 0.7 5.01 0.41 1.85e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs9486715 0.867 rs4240553 chr6:96965324 T/C cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs8030485 0.730 rs57488047 chr15:79403002 T/C cg17916960 chr15:79447300 NA 0.34 4.75 0.39 5.54e-6 Left ventricle wall thickness; TGCT cis rs7824557 0.603 rs11250130 chr8:11214455 C/T cg21775007 chr8:11205619 TDH -0.66 -6.56 -0.51 1.34e-9 Retinal vascular caliber; TGCT cis rs854765 0.547 rs12150369 chr17:17911014 G/A cg04398451 chr17:18023971 MYO15A -0.32 -5.07 -0.41 1.44e-6 Total body bone mineral density; TGCT cis rs2455799 0.559 rs9813577 chr3:15909323 C/T cg12172478 chr3:16357591 RFTN1 -0.36 -5.49 -0.44 2.18e-7 Mean platelet volume; TGCT cis rs9322193 0.923 rs9689716 chr6:149976798 G/A cg13206674 chr6:150067644 NUP43 0.51 4.47 0.37 1.75e-5 Lung cancer; TGCT cis rs6752107 0.901 rs2289477 chr2:234160345 T/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.86 0.4 3.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT trans rs77457752 0.525 rs10121526 chr9:13898615 G/A cg25510823 chr7:47085976 NA 0.45 6.68 0.51 7.21e-10 Breast cancer; TGCT cis rs6964587 0.967 rs10279943 chr7:91587477 G/C cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6598955 0.543 rs60676610 chr1:26543421 G/C cg04990556 chr1:26633338 UBXN11 0.81 7.35 0.55 2.29e-11 Obesity-related traits; TGCT cis rs5769707 0.681 rs9616329 chr22:50026314 G/A cg06623630 chr22:50017776 C22orf34 -0.26 -4.49 -0.37 1.62e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6952808 0.601 rs3778978 chr7:2159817 A/G cg04267008 chr7:1944627 MAD1L1 -0.38 -5.2 -0.42 7.97e-7 Bipolar disorder and schizophrenia; TGCT cis rs7666738 0.830 rs28728124 chr4:99001116 G/T cg17366294 chr4:99064904 C4orf37 0.69 6.82 0.52 3.56e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs13082711 0.954 rs34772035 chr3:27468872 C/G cg02860705 chr3:27208620 NA 0.35 4.83 0.4 3.9e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7213347 0.707 rs9898390 chr17:2177484 C/G cg20777128 chr17:1945076 DPH1;OVCA2 -0.5 -4.57 -0.38 1.17e-5 Total body bone mineral density; TGCT cis rs2268241 0.877 rs17887186 chr21:34779202 G/A cg14850771 chr21:34775459 IFNGR2 0.61 5.23 0.43 6.88e-7 Obesity-related traits; TGCT cis rs71435601 0.574 rs522250 chr2:21387113 T/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs7584330 0.780 rs2292884 chr2:238443226 A/G cg14458575 chr2:238380390 NA 0.45 6.9 0.53 2.38e-10 Prostate cancer; TGCT cis rs7267979 0.834 rs6115100 chr20:25225938 C/A cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs62481355 1.000 rs62481355 chr7:127201664 C/T cg25922125 chr7:127225783 GCC1 -0.42 -4.44 -0.37 1.93e-5 Type 2 diabetes; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg14851468 chr5:179071604 C5orf60 0.22 4.54 0.38 1.32e-5 Lung cancer; TGCT cis rs6540559 0.605 rs3753518 chr1:209977964 G/C cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs59197085 0.636 rs730931 chr7:128462273 C/G cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg25767906 chr1:53392781 SCP2 -0.55 -6.3 -0.49 4.75e-9 Monocyte count; TGCT cis rs208520 0.526 rs9294682 chr6:66795159 G/A cg07460842 chr6:66804631 NA -1.08 -15.95 -0.82 8.03e-32 Exhaled nitric oxide output; TGCT cis rs2153535 0.541 rs6932434 chr6:8467679 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9911578 1.000 rs4636974 chr17:56965373 C/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs4953076 0.573 rs6544746 chr2:44407985 C/T cg00619915 chr2:44497795 NA -0.23 -5.1 -0.42 1.24e-6 Height; TGCT cis rs12887734 0.546 rs12885509 chr14:104273325 T/C cg26031613 chr14:104095156 KLC1 -0.73 -6.28 -0.49 5.3e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7829975 0.688 rs7837587 chr8:8378992 T/C cg06636001 chr8:8085503 FLJ10661 0.77 7.37 0.55 2.12e-11 Mood instability; TGCT trans rs1814175 0.791 rs11040472 chr11:49703116 C/T cg15704280 chr7:45808275 SEPT13 -0.71 -8.23 -0.59 2.14e-13 Height; TGCT cis rs1062177 0.756 rs2964588 chr5:151118386 C/T cg00977110 chr5:151150581 G3BP1 -0.4 -4.67 -0.39 7.7e-6 Preschool internalizing problems; TGCT cis rs12142240 0.659 rs72677602 chr1:46837487 G/A cg00530320 chr1:46809349 NSUN4 0.27 5.45 0.44 2.58e-7 Menopause (age at onset); TGCT cis rs9549367 0.774 rs9549696 chr13:113875062 C/T cg00898013 chr13:113819073 PROZ -0.37 -4.73 -0.39 5.96e-6 Platelet distribution width; TGCT cis rs9341808 0.618 rs6916507 chr6:80862265 T/C cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs1215050 0.874 rs2167893 chr4:99048464 A/T cg05340658 chr4:99064831 C4orf37 0.42 5.03 0.41 1.7e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4819052 0.851 rs8126930 chr21:46671715 A/G cg06618935 chr21:46677482 NA -0.37 -5.68 -0.45 9.21e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs1008375 0.931 rs1860592 chr4:17577028 C/G cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7586879 0.639 rs7580081 chr2:25097072 G/C cg15423357 chr2:25149977 NA 0.47 4.6 0.38 1.02e-5 Body mass index; TGCT cis rs6688613 0.649 rs11584352 chr1:166850372 T/C cg07049167 chr1:166818506 POGK 0.25 5.23 0.43 6.88e-7 Refractive astigmatism; TGCT cis rs11190604 1.000 rs74210981 chr10:102287520 C/T cg23241863 chr10:102295624 HIF1AN 0.66 4.87 0.4 3.38e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1847202 0.826 rs7640629 chr3:72925997 C/T cg25664220 chr3:72788482 NA -0.38 -4.88 -0.4 3.13e-6 Motion sickness; TGCT cis rs3125734 0.572 rs7896627 chr10:64046354 T/G cg09941381 chr10:64027924 RTKN2 -0.33 -4.9 -0.4 2.94e-6 Rheumatoid arthritis; TGCT cis rs7811142 1.000 rs11771241 chr7:99994785 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs7940866 0.838 rs12790299 chr11:130803634 A/G cg05962950 chr11:130786565 SNX19 0.68 6.61 0.51 1.02e-9 Schizophrenia; TGCT cis rs7552404 1.000 rs72686191 chr1:76218319 G/T cg22875332 chr1:76189707 ACADM 0.78 8.98 0.63 3.55e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6967414 0.786 rs6948965 chr7:6758547 G/A cg09896999 chr7:6746977 ZNF12 -0.59 -6.54 -0.51 1.45e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs7582180 0.629 rs893416 chr2:100957443 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.926 rs1060489 chr20:61665921 C/T cg03213289 chr20:61660250 NA 0.7 10.11 0.67 6.94e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs59197085 0.515 rs2291573 chr7:128444820 A/G cg00260937 chr7:128520193 KCP 0.46 5.12 0.42 1.15e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs2255336 0.702 rs7964772 chr12:10520097 G/A cg16084090 chr12:10586130 KLRC2 0.3 4.65 0.39 8.37e-6 Blood protein levels; TGCT cis rs9467773 1.000 rs9393731 chr6:26529374 C/T cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9486719 1.000 rs2971603 chr6:97035418 C/T cg06623918 chr6:96969491 KIAA0776 -1.04 -10.25 -0.68 3.11e-18 Migraine;Coronary artery disease; TGCT cis rs909341 0.868 rs2236508 chr20:62333115 G/A cg14758556 chr20:62440591 NA 0.29 4.48 0.37 1.71e-5 Atopic dermatitis; TGCT cis rs3824867 0.920 rs7101772 chr11:47449378 A/G cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs72949976 0.934 rs13406406 chr2:214034826 C/T cg08319019 chr2:214017104 IKZF2 -0.78 -7.15 -0.54 6.61e-11 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs3740393 0.562 rs11191389 chr10:104523018 C/T cg05855489 chr10:104503620 C10orf26 0.76 6.34 0.5 3.8e-9 Microalbuminuria; TGCT cis rs4455778 0.659 rs10268788 chr7:49048110 G/A cg26309511 chr7:48887640 NA 0.42 4.98 0.41 2.08e-6 Lung cancer in never smokers; TGCT cis rs60871478 0.588 rs6952577 chr7:872100 C/T cg15782153 chr7:917662 C7orf20 -0.52 -4.78 -0.39 4.84e-6 Cerebrospinal P-tau181p levels; TGCT cis rs473651 0.935 rs541128 chr2:239336449 A/G cg08773314 chr2:239334832 ASB1 0.45 7.5 0.56 1.07e-11 Multiple system atrophy; TGCT cis rs589448 0.902 rs315134 chr12:69762713 G/A cg11871910 chr12:69753446 YEATS4 0.88 10.41 0.68 1.28e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs9926296 0.568 rs4420527 chr16:89814188 C/T cg04287289 chr16:89883240 FANCA -0.91 -11.11 -0.71 2.56e-20 Vitiligo; TGCT cis rs4730250 0.707 rs6946931 chr7:106788621 G/T cg02696742 chr7:106810147 HBP1 -0.71 -6.08 -0.48 1.35e-8 Osteoarthritis; TGCT cis rs2070488 1.000 rs2276540 chr3:38512507 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.89 9.58 0.65 1.34e-16 Electrocardiographic conduction measures; TGCT cis rs12210905 0.610 rs72845208 chr6:27395664 C/A cg08851530 chr6:28072375 NA 1.34 6.07 0.48 1.44e-8 Hip circumference adjusted for BMI; TGCT cis rs7552404 0.731 rs5745491 chr1:76350159 T/G cg22875332 chr1:76189707 ACADM -0.67 -6.92 -0.53 2.12e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs12477438 0.765 rs7607578 chr2:99669771 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs1218582 0.741 rs10908447 chr1:154869742 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.65 -6.51 -0.5 1.68e-9 Prostate cancer; TGCT cis rs10501293 0.746 rs7126731 chr11:43007348 T/C cg03447554 chr11:43094025 NA 0.44 6.31 0.49 4.57e-9 Cognitive performance; TGCT cis rs709400 1.000 rs10135248 chr14:104122310 T/C cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT trans rs17471911 0.708 rs11189933 chr10:100772538 A/T cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs12142240 0.698 rs66847432 chr1:46832013 G/A cg00530320 chr1:46809349 NSUN4 0.29 6.03 0.48 1.71e-8 Menopause (age at onset); TGCT cis rs8180040 0.654 rs13078131 chr3:47204939 G/T cg27129171 chr3:47204927 SETD2 0.77 9.86 0.66 2.77e-17 Colorectal cancer; TGCT cis rs1729951 0.575 rs75976 chr3:136700455 G/A cg12473912 chr3:136751656 NA 0.39 6.34 0.49 3.84e-9 Neuroticism; TGCT cis rs7949030 0.626 rs11231144 chr11:62328038 A/G cg13298116 chr11:62369859 EML3;MTA2 0.66 9.69 0.66 7.3e-17 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT trans rs4824093 0.610 rs77128035 chr22:50241024 C/T cg09872104 chr7:134855509 C7orf49 -0.9 -7.32 -0.55 2.72e-11 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs11148252 0.553 rs2147692 chr13:53287023 C/G cg00495681 chr13:53174319 NA 0.73 7.61 0.56 6.01e-12 Lewy body disease; TGCT cis rs7829975 0.811 rs7011229 chr8:8543324 T/C cg06636001 chr8:8085503 FLJ10661 -0.6 -5.0 -0.41 1.92e-6 Mood instability; TGCT trans rs797680 0.856 rs9432681 chr1:93761896 A/G cg27528825 chr2:159282178 CCDC148 0.34 6.71 0.52 6.19e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2486288 0.587 rs12899942 chr15:45547280 T/C cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs10193935 0.901 rs1439231 chr2:42542884 G/A cg27598129 chr2:42591480 NA -0.4 -5.45 -0.44 2.66e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1775715 0.737 rs1023207 chr10:32094890 C/A cg14930904 chr10:32216787 ARHGAP12 0.52 5.1 0.42 1.26e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg05896524 chr21:47604654 C21orf56 0.42 4.45 0.37 1.91e-5 Testicular germ cell tumor; TGCT trans rs6089829 0.926 rs6011552 chr20:61667894 T/C cg13615516 chr5:77269221 NA 0.66 8.06 0.59 5.55e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs12681288 0.550 rs58295701 chr8:962136 T/C cg04851639 chr8:1020857 NA -0.3 -5.08 -0.41 1.36e-6 Schizophrenia; TGCT cis rs644799 0.710 rs10831433 chr11:95519787 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.84 9.19 0.64 1.12e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs17253792 0.822 rs9323289 chr14:56106784 G/C cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs11264213 0.901 rs12031138 chr1:36407806 C/T cg07093915 chr1:36184400 C1orf216 -0.65 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT cis rs28830936 0.510 rs2412640 chr15:42124082 C/T cg17847044 chr15:42102381 MAPKBP1 0.17 4.73 0.39 6.1e-6 Diastolic blood pressure; TGCT cis rs523522 0.962 rs10849757 chr12:120964014 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg10150615 chr22:24372951 LOC391322 -0.74 -7.98 -0.58 8.36e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7226408 0.857 rs10502667 chr18:34482449 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT trans rs1814175 0.791 rs7395713 chr11:49877887 A/G cg03929089 chr4:120376271 NA -0.71 -8.03 -0.58 6.31e-13 Height; TGCT cis rs4654899 1.000 rs6669102 chr1:21355543 A/G cg01072550 chr1:21505969 NA -0.48 -7.78 -0.57 2.49e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7226408 0.857 rs72892516 chr18:34665048 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2204008 0.550 rs11495600 chr12:38126654 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT trans rs28735056 0.904 rs11520415 chr18:77620620 C/T cg05926928 chr17:57297772 GDPD1 0.64 6.68 0.51 7.09e-10 Schizophrenia; TGCT cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg03161606 chr19:29218774 NA 0.62 6.0 0.47 2e-8 Methadone dose in opioid dependence; TGCT cis rs6740731 0.518 rs16823846 chr2:145299944 C/T cg07679370 chr2:145795797 NA 0.27 5.36 0.43 3.83e-7 Coronary artery disease; TGCT cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg26531700 chr6:26746687 NA 0.6 5.81 0.46 5e-8 Intelligence (multi-trait analysis); TGCT trans rs9951602 0.512 rs7241419 chr18:76640778 C/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.78 0.75 2.24e-24 Obesity-related traits; TGCT cis rs10782582 0.593 rs11802717 chr1:76124648 C/T cg10523679 chr1:76189770 ACADM -0.7 -7.51 -0.56 9.94e-12 Daytime sleep phenotypes; TGCT cis rs9325144 0.647 rs12830095 chr12:38864199 C/T cg10518543 chr12:38710700 ALG10B -0.49 -4.46 -0.37 1.81e-5 Morning vs. evening chronotype; TGCT cis rs7959452 0.535 rs7308481 chr12:69659299 A/G cg11871910 chr12:69753446 YEATS4 0.63 6.24 0.49 6.36e-9 Blood protein levels; TGCT cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg06238570 chr21:40685208 BRWD1 0.72 6.84 0.52 3.16e-10 Cognitive function; TGCT cis rs4319547 0.955 rs6489159 chr12:123112806 G/A cg23029597 chr12:123009494 RSRC2 -0.33 -5.35 -0.43 4e-7 Body mass index; TGCT cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg12386194 chr3:101231763 SENP7 0.52 5.01 0.41 1.87e-6 Colorectal cancer; TGCT trans rs3780486 0.846 rs7849148 chr9:33138352 A/T cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg20637647 chr7:64974828 NA 0.98 5.48 0.44 2.3e-7 Diabetic kidney disease; TGCT cis rs9611565 0.608 rs202652 chr22:41838792 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.71 0.39 6.63e-6 Vitiligo; TGCT cis rs7824557 0.628 rs7008205 chr8:11197323 T/G cg21775007 chr8:11205619 TDH 0.69 6.81 0.52 3.8e-10 Retinal vascular caliber; TGCT cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs1577917 0.740 rs9344542 chr6:86393905 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.5 4.63 0.38 9.26e-6 Response to antipsychotic treatment; TGCT cis rs2576037 0.583 rs1465722 chr18:44564499 C/G cg23302884 chr18:44338147 ST8SIA5 0.4 4.79 0.4 4.67e-6 Personality dimensions; TGCT cis rs7804356 0.651 rs1023712 chr7:26803163 A/C cg03456212 chr7:26904342 SKAP2 -0.54 -4.6 -0.38 1.04e-5 Type 1 diabetes; TGCT cis rs6684514 1.000 rs12023438 chr1:156254358 A/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7267979 0.789 rs6076347 chr20:25398790 C/T cg16686733 chr20:25566563 NINL -0.49 -4.64 -0.38 8.6e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17607347 0.542 rs2336437 chr16:72465604 G/T cg06220725 chr16:72042591 DHODH -0.73 -4.83 -0.4 3.96e-6 Intelligence (multi-trait analysis); TGCT trans rs877282 0.853 rs7069720 chr10:754487 A/G cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs2404602 1.000 rs12441433 chr15:76816015 G/A cg22467129 chr15:76604101 ETFA -0.49 -5.48 -0.44 2.3e-7 Blood metabolite levels; TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs4148883 0.603 rs6833176 chr4:100131163 G/C cg12011299 chr4:100065546 ADH4 -0.37 -5.48 -0.44 2.32e-7 Alcohol dependence; TGCT cis rs6908034 0.660 rs7746588 chr6:19804640 C/T cg02682789 chr6:19804855 NA 0.92 5.24 0.43 6.7e-7 Endometriosis;Deep ovarian and/or rectovaginal disease with dense adhesions; TGCT cis rs12682352 0.602 rs11783966 chr8:8665147 A/G cg06636001 chr8:8085503 FLJ10661 -0.65 -5.59 -0.45 1.38e-7 Neuroticism; TGCT cis rs4771122 0.728 rs7992289 chr13:28036430 G/A cg22138327 chr13:27999177 GTF3A -0.72 -5.79 -0.46 5.36e-8 Body mass index; TGCT trans rs459571 0.959 rs2520099 chr9:136918139 T/C cg09836344 chr4:1243392 C4orf42;CTBP1 -0.77 -8.34 -0.6 1.17e-13 Platelet distribution width; TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg22764044 chr5:178986830 RUFY1 -0.5 -5.66 -0.45 9.95e-8 Lung cancer; TGCT cis rs6540559 0.673 rs6698154 chr1:210007777 A/G cg21951975 chr1:209979733 IRF6 0.64 4.82 0.4 4.12e-6 Cleft lip with or without cleft palate; TGCT cis rs8078723 1.000 rs4794824 chr17:38179290 G/A cg17467752 chr17:38218738 THRA 0.53 5.08 0.42 1.33e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7216064 1.000 rs56404791 chr17:65893019 T/G cg12091567 chr17:66097778 LOC651250 -0.84 -6.17 -0.48 8.94e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6032067 0.636 rs6032094 chr20:43912637 G/A cg16667508 chr20:43936853 MATN4;RBPJL -0.48 -7.2 -0.54 5.02e-11 Blood protein levels; TGCT cis rs3008870 0.920 rs3008865 chr1:67402838 T/C cg11518657 chr1:67396239 MIER1 0.54 4.68 0.39 7.24e-6 Lymphocyte percentage of white cells; TGCT cis rs548181 1.000 rs548181 chr11:125461709 A/G cg03464685 chr11:125439445 EI24 1.2 9.28 0.64 6.78e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9926296 0.528 rs4785721 chr16:89839997 G/A cg26513180 chr16:89883248 FANCA 1.07 14.86 0.8 2.59e-29 Vitiligo; TGCT trans rs77457752 0.690 rs10123356 chr9:13912564 T/C cg18948646 chr4:83674694 SCD5;MIR575 0.54 6.62 0.51 9.53e-10 Breast cancer; TGCT cis rs295140 0.605 rs3769471 chr2:201195403 G/A cg23649088 chr2:200775458 C2orf69 -0.27 -4.49 -0.37 1.62e-5 QT interval; TGCT cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.58e-9 Gut microbiome composition (summer); TGCT cis rs6964587 1.000 rs3753108 chr7:91629984 T/G cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs4803468 1.000 rs2241706 chr19:41912807 A/G cg09537434 chr19:41945824 ATP5SL -0.92 -10.69 -0.69 2.72e-19 Height; TGCT cis rs10392 0.543 rs16987679 chr20:37557185 G/C cg27552599 chr20:37590471 DHX35 0.37 4.44 0.37 2e-5 Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis; TGCT cis rs6671200 0.607 rs7528790 chr1:95709074 A/G cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs3096299 0.719 rs2965818 chr16:89510494 A/G cg06640241 chr16:89574553 SPG7 0.76 8.51 0.61 4.86e-14 Multiple myeloma (IgH translocation); TGCT cis rs4727027 0.651 rs12704068 chr7:148856153 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.57 5.0 0.41 1.91e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs826838 1.000 rs34254519 chr12:39041235 G/A cg13010199 chr12:38710504 ALG10B 0.78 6.38 0.5 3.22e-9 Heart rate; TGCT cis rs40363 0.645 rs6501177 chr16:3523681 C/T cg22508957 chr16:3507546 NAT15 0.5 5.79 0.46 5.49e-8 Tuberculosis; TGCT cis rs9467711 0.651 rs13200797 chr6:26122957 G/A cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.57 -4.54 -0.38 1.33e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.765 rs10181422 chr2:99558970 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.52 -0.38 1.45e-5 Chronic sinus infection; TGCT cis rs2456568 0.548 rs6483280 chr11:93661592 T/C cg16099599 chr11:93583650 C11orf90 -0.39 -4.66 -0.39 7.9e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs908922 0.676 rs528427 chr1:152511507 G/C cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs694739 0.628 rs645078 chr11:64135298 A/C cg02228329 chr11:64053129 BAD;GPR137 0.72 7.05 0.53 1.1e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs3125734 0.633 rs1368157 chr10:64001114 T/C cg09941381 chr10:64027924 RTKN2 -0.37 -5.59 -0.45 1.41e-7 Rheumatoid arthritis; TGCT cis rs769267 0.965 rs4808200 chr19:19554803 C/T cg03709012 chr19:19516395 GATAD2A 0.74 6.12 0.48 1.15e-8 Tonsillectomy; TGCT cis rs10883723 0.810 rs7093028 chr10:104259417 A/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2239547 0.522 rs2581805 chr3:52979050 T/C cg11645453 chr3:52864694 ITIH4 -0.32 -5.24 -0.43 6.56e-7 Schizophrenia; TGCT cis rs2070488 1.000 rs2268757 chr3:38505853 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.89 9.83 0.66 3.21e-17 Electrocardiographic conduction measures; TGCT cis rs514475 0.526 rs12197157 chr6:137952912 C/T cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs6728642 0.803 rs11891457 chr2:97632449 G/T cg26665480 chr2:98280029 ACTR1B -0.91 -5.94 -0.47 2.67e-8 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs7666738 0.830 rs6532701 chr4:98745134 C/T cg18180107 chr4:99064573 C4orf37 0.53 5.03 0.41 1.69e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9368481 0.729 rs9379948 chr6:26944783 T/G cg18867708 chr6:26865862 GUSBL1 0.34 4.49 0.37 1.61e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs4595586 0.545 rs6580894 chr12:39371951 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.61 0.38 9.99e-6 Morning vs. evening chronotype; TGCT cis rs2455799 0.559 rs7635539 chr3:15922908 A/G cg12172478 chr3:16357591 RFTN1 0.34 5.1 0.42 1.25e-6 Mean platelet volume; TGCT cis rs801193 0.660 rs2659897 chr7:66187715 A/G cg18876405 chr7:65276391 NA -0.31 -4.6 -0.38 1.03e-5 Aortic root size; TGCT cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.49 0.61 5.35e-14 Platelet count; TGCT cis rs7666738 0.830 rs7678911 chr4:99057430 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6940638 0.688 rs9393795 chr6:27217719 G/C cg26531700 chr6:26746687 NA -0.58 -5.11 -0.42 1.21e-6 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.724 rs2572398 chr8:11178093 A/C cg21775007 chr8:11205619 TDH 0.56 5.14 0.42 1.05e-6 Retinal vascular caliber; TGCT cis rs79349575 0.783 rs903567 chr17:46980318 C/T cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs2721195 0.845 rs3757966 chr8:145744618 G/A cg15320075 chr8:145703422 NA 0.7 7.12 0.54 7.58e-11 Age at first birth; TGCT cis rs55692411 0.537 rs35012435 chr3:50031840 C/T cg14019146 chr3:50243930 SLC38A3 -0.21 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs295137 0.799 rs4145969 chr2:201139961 C/T cg04283868 chr2:201171347 SPATS2L 0.47 4.51 0.38 1.51e-5 Asthma (bronchodilator response); TGCT cis rs9583531 0.600 rs3809344 chr13:111358705 G/A cg24331049 chr13:111365604 ING1 0.76 7.31 0.55 2.95e-11 Coronary artery disease; TGCT cis rs2862064 0.872 rs6555822 chr5:156473185 A/G cg12943317 chr5:156479607 HAVCR1 -0.46 -5.59 -0.45 1.35e-7 Platelet count; TGCT cis rs7666738 0.830 rs4440224 chr4:99044924 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10838634 0.901 rs57485117 chr11:46803700 C/G cg18332754 chr11:46939436 LRP4 0.84 4.54 0.38 1.29e-5 Schizophrenia; TGCT cis rs9611565 0.513 rs739135 chr22:42090069 A/C cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Vitiligo; TGCT cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg17971929 chr21:40555470 PSMG1 0.96 9.05 0.63 2.44e-15 Cognitive function; TGCT cis rs4808199 0.895 rs10421505 chr19:19459554 C/T cg03709012 chr19:19516395 GATAD2A 0.8 6.46 0.5 2.13e-9 Nonalcoholic fatty liver disease; TGCT cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg05738196 chr6:26577821 NA 0.87 9.67 0.66 7.91e-17 Intelligence (multi-trait analysis); TGCT cis rs6684514 0.961 rs72710222 chr1:156285995 T/C cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9303401 0.538 rs10515155 chr17:56481944 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.73 6.73 0.52 5.72e-10 Cognitive test performance; TGCT cis rs28595532 0.844 rs115411027 chr4:119490685 T/C cg14228332 chr4:119757509 SEC24D 1.0 5.75 0.46 6.54e-8 Cannabis dependence symptom count; TGCT cis rs11577318 0.853 rs3795684 chr1:26632781 C/T cg04990556 chr1:26633338 UBXN11 -0.63 -5.77 -0.46 6.01e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs4383453 0.539 rs903571 chr3:123101250 A/C cg04890266 chr3:123102914 ADCY5 -0.49 -8.13 -0.59 3.67e-13 Gestational age at birth (maternal effect); TGCT cis rs13326165 0.760 rs35133416 chr3:52359040 C/T cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6912958 0.559 rs242279 chr6:88048191 A/G cg04972856 chr6:88032051 C6orf162;GJB7 0.4 4.71 0.39 6.65e-6 Monocyte percentage of white cells; TGCT trans rs10203711 1.000 rs4994756 chr2:239567125 T/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6840360 0.870 rs6814554 chr4:152454334 G/A cg17479576 chr4:152424074 FAM160A1 -0.55 -6.17 -0.48 8.74e-9 Intelligence (multi-trait analysis); TGCT cis rs8013055 0.846 rs35723046 chr14:105970548 C/T cg19700328 chr14:106028568 NA -0.53 -5.76 -0.46 6.36e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs644799 0.710 rs10831429 chr11:95508524 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.81 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs7091068 0.671 rs588912 chr10:95402929 T/C cg20715218 chr10:95462985 C10orf4 -0.54 -5.14 -0.42 1.02e-6 Urinary tract infection frequency; TGCT cis rs2887571 0.580 rs34992552 chr12:1637688 G/A cg01940102 chr12:1095972 NA 0.26 4.78 0.39 4.92e-6 Bone mineral density; TGCT cis rs40363 0.951 rs72778117 chr16:3531827 T/C cg05754148 chr16:3507555 NAT15 0.47 4.64 0.38 8.58e-6 Tuberculosis; TGCT cis rs1865760 0.865 rs9467650 chr6:25958235 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs12479064 0.724 rs2305352 chr2:100015124 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -4.71 -0.39 6.5e-6 Chronic sinus infection; TGCT cis rs2663905 0.611 rs1509559 chr15:81391411 G/A cg27045999 chr15:81426544 C15orf26 -0.55 -5.52 -0.44 1.89e-7 QT interval (drug interaction); TGCT cis rs4851254 0.584 rs35774174 chr2:100655130 T/A cg07810366 chr2:100720526 AFF3 -0.47 -4.75 -0.39 5.46e-6 Intelligence (multi-trait analysis); TGCT cis rs7786808 0.776 rs11983316 chr7:158209742 A/G cg01191920 chr7:158217561 PTPRN2 -0.42 -6.48 -0.5 1.95e-9 Obesity-related traits; TGCT cis rs1577917 0.958 rs13213551 chr6:86608701 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs617219 0.597 rs10474581 chr5:78578884 G/A cg23987322 chr5:78407566 BHMT -0.36 -4.66 -0.39 8.06e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6951245 0.554 rs4724294 chr7:1139695 G/A cg09177884 chr7:1199841 ZFAND2A -0.72 -5.71 -0.46 7.86e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10197940 0.662 rs10175134 chr2:152299355 G/A cg06191203 chr2:152266755 RIF1 -0.78 -7.31 -0.55 2.89e-11 Lung cancer; TGCT cis rs6570726 0.935 rs385185 chr6:145814992 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs6582630 0.519 rs8189618 chr12:38276281 A/C cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.19e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs941408 0.515 rs2110118 chr19:2775144 T/C cg06609049 chr19:2785107 THOP1 1.11 12.98 0.76 7.5e-25 Total cholesterol levels; TGCT cis rs3087591 0.922 rs2905801 chr17:29524974 C/T cg24425628 chr17:29625626 OMG;NF1 0.42 6.22 0.49 7.06e-9 Hip circumference; TGCT cis rs796364 0.570 rs4673491 chr2:200669108 A/G cg17644776 chr2:200775616 C2orf69 0.34 4.59 0.38 1.07e-5 Schizophrenia; TGCT cis rs7617773 0.832 rs6775114 chr3:48182620 G/C cg11946769 chr3:48343235 NME6 -0.59 -5.35 -0.43 4.07e-7 Coronary artery disease; TGCT cis rs8032315 0.965 rs12906125 chr15:91427612 G/A cg04510874 chr15:91427884 FES 0.52 5.78 0.46 5.8e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs4919687 0.550 rs12775883 chr10:104485301 G/A cg05855489 chr10:104503620 C10orf26 0.56 4.51 0.38 1.5e-5 Colorectal cancer; TGCT cis rs174479 0.743 rs174464 chr11:61657926 A/G cg01500311 chr11:61656094 FADS3 0.28 5.03 0.41 1.68e-6 Sphingolipid levels; TGCT cis rs854765 0.583 rs11078405 chr17:17824978 G/T cg09796270 chr17:17721594 SREBF1 0.28 5.66 0.45 9.89e-8 Total body bone mineral density; TGCT cis rs9902453 0.866 rs4795529 chr17:28443549 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 7.28 0.55 3.38e-11 Coffee consumption (cups per day); TGCT cis rs801193 1.000 rs10274773 chr7:66133578 G/A cg18876405 chr7:65276391 NA -0.34 -5.19 -0.42 8.37e-7 Aortic root size; TGCT cis rs7267979 0.866 rs2424698 chr20:25256106 C/T cg16686733 chr20:25566563 NINL 0.62 6.43 0.5 2.54e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4819052 0.851 rs2838844 chr21:46670733 A/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.57 0.38 1.15e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs986417 0.901 rs10483726 chr14:61039476 A/G cg27398547 chr14:60952738 C14orf39 1.43 10.61 0.69 4.17e-19 Gut microbiota (bacterial taxa); TGCT cis rs6540559 0.546 rs57315825 chr1:210030197 C/T cg22029157 chr1:209979665 IRF6 0.81 6.07 0.48 1.45e-8 Cleft lip with or without cleft palate; TGCT cis rs9534288 0.830 rs940 chr13:46627480 C/G cg15192986 chr13:46630673 CPB2 -0.52 -6.68 -0.51 7.09e-10 Blood protein levels; TGCT cis rs6951245 1.000 rs75488469 chr7:1102122 A/G cg18402987 chr7:1209562 NA 0.77 6.51 0.5 1.7e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1532993 0.518 rs6532689 chr4:98616963 C/A cg05340658 chr4:99064831 C4orf37 -0.37 -4.44 -0.37 1.98e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs1723838 1.000 rs1792164 chr11:73548670 G/A cg26954736 chr11:73693896 UCP2 -1.1 -4.61 -0.38 9.8e-6 Obesity-related traits; TGCT cis rs1215050 0.791 rs2865942 chr4:98737709 G/C cg17366294 chr4:99064904 C4orf37 0.52 5.57 0.45 1.54e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11030122 0.547 rs10767723 chr11:3955026 G/T cg18678763 chr11:4115507 RRM1 -0.39 -4.76 -0.39 5.24e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs17473412 0.609 rs6875515 chr5:122864629 G/A cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs362272 0.545 rs3129308 chr4:3309272 C/T cg22655196 chr4:3374909 RGS12 0.26 5.36 0.43 3.83e-7 Serum sulfate level; TGCT cis rs12681287 0.546 rs11539113 chr8:87497176 G/A cg27223183 chr8:87520930 FAM82B -0.94 -6.79 -0.52 4.14e-10 Caudate activity during reward; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg25151919 chr3:44754333 ZNF502 -0.43 -5.01 -0.41 1.8e-6 Depressive symptoms; TGCT cis rs651907 0.557 rs13069443 chr3:101373305 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs1218582 0.740 rs1977879 chr1:154879743 G/A cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs765787 0.530 rs7165889 chr15:45531640 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs13272623 0.502 rs268562 chr8:71494780 G/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.71 -5.89 -0.47 3.47e-8 IgG glycosylation; TGCT cis rs13191362 0.507 rs2023038 chr6:163119280 C/G cg21926612 chr6:163149169 PACRG;PARK2 -0.61 -5.69 -0.45 8.8e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs2610739 0.591 rs12211793 chr6:89189968 G/C cg05764691 chr16:22927585 HS3ST2 0.41 6.82 0.52 3.51e-10 IgG glycosylation; TGCT cis rs6912958 0.703 rs9353483 chr6:88097180 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.4 5.17 0.42 8.97e-7 Monocyte percentage of white cells; TGCT trans rs2727020 0.553 rs3862350 chr11:49595912 A/C cg15704280 chr7:45808275 SEPT13 -0.61 -6.89 -0.53 2.47e-10 Coronary artery disease; TGCT cis rs1153858 1.000 rs1145081 chr15:45679667 C/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs61931739 0.500 rs11053198 chr12:34444013 G/C cg06521331 chr12:34319734 NA -0.28 -4.51 -0.38 1.47e-5 Morning vs. evening chronotype; TGCT cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg17554472 chr22:41940697 POLR3H -0.51 -5.5 -0.44 2.09e-7 Vitiligo; TGCT cis rs16958440 0.867 rs12326412 chr18:44683594 A/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs6831352 0.879 rs1984364 chr4:100070783 A/C cg12011299 chr4:100065546 ADH4 -0.43 -5.07 -0.41 1.44e-6 Alcohol dependence; TGCT cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg06640241 chr16:89574553 SPG7 0.79 8.8 0.62 1.01e-14 Multiple myeloma (IgH translocation); TGCT cis rs11971779 0.680 rs73154134 chr7:139039951 G/A cg07862535 chr7:139043722 LUC7L2 0.7 5.21 0.42 7.8e-7 Diisocyanate-induced asthma; TGCT cis rs4819052 0.788 rs9978857 chr21:46705155 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.73 6.65 0.51 8.21e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2832191 0.765 rs2832162 chr21:30461808 G/A cg08807101 chr21:30365312 RNF160 0.65 6.08 0.48 1.34e-8 Dental caries; TGCT cis rs7727544 0.606 rs11950562 chr5:131652529 A/C cg24060327 chr5:131705240 SLC22A5 -0.53 -5.7 -0.46 8.23e-8 Blood metabolite levels; TGCT cis rs7258465 1.000 rs10411009 chr19:18606266 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.68 0.39 7.45e-6 Breast cancer; TGCT cis rs7731657 0.537 rs2905534 chr5:130242005 C/T cg08523029 chr5:130500466 HINT1 -0.58 -4.84 -0.4 3.8e-6 Fasting plasma glucose; TGCT cis rs4919669 0.668 rs10883760 chr10:104419465 G/T cg05855489 chr10:104503620 C10orf26 0.8 4.59 0.38 1.05e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs79349575 0.783 rs4794003 chr17:47029904 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs9611565 0.694 rs202616 chr22:41822221 C/G cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs3784262 0.740 rs2119859 chr15:58254745 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.18 -0.49 8.37e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9330316 0.632 rs6723295 chr2:110363704 G/A cg25199208 chr2:109402912 CCDC138 -0.41 -4.44 -0.37 1.99e-5 Schizophrenia; TGCT cis rs9549367 0.789 rs12869947 chr13:113896156 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.61 -0.45 1.25e-7 Platelet distribution width; TGCT cis rs5769765 0.837 rs4824110 chr22:50271631 T/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs10782582 0.593 rs12131493 chr1:76139172 G/A cg10523679 chr1:76189770 ACADM -0.68 -7.05 -0.53 1.12e-10 Daytime sleep phenotypes; TGCT cis rs7072216 0.763 rs7910247 chr10:100172252 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs838147 0.760 rs412712 chr19:49234299 A/T cg13540341 chr19:49222985 MAMSTR 0.31 4.48 0.37 1.66e-5 Dietary macronutrient intake; TGCT cis rs11203032 1.000 rs11203031 chr10:90964395 G/T cg16672925 chr10:90967113 CH25H 0.69 4.68 0.39 7.41e-6 Heart failure; TGCT cis rs6426558 0.502 rs1929858 chr1:227220175 C/A cg10327440 chr1:227177885 CDC42BPA 0.62 7.52 0.56 9.35e-12 Neutrophil percentage of white cells; TGCT cis rs861020 0.771 rs629150 chr1:209998467 C/T cg05527609 chr1:210001259 C1orf107 1.02 8.92 0.63 5.16e-15 Orofacial clefts; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.08e-7 Lymphocyte counts; TGCT cis rs9914544 0.545 rs2305064 chr17:18770733 G/A cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs12188164 0.930 rs72717440 chr5:449701 A/T cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs7572733 0.515 rs12619300 chr2:198786490 A/C cg00792783 chr2:198669748 PLCL1 -0.57 -5.14 -0.42 1.03e-6 Dermatomyositis; TGCT cis rs9486719 1.000 rs11752584 chr6:96884952 C/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7666738 0.830 rs10025174 chr4:98914172 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.99 0.41 1.98e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9926296 0.687 rs258317 chr16:89732238 C/T cg01097406 chr16:89675127 NA 0.34 5.95 0.47 2.55e-8 Vitiligo; TGCT cis rs4319547 1.000 rs9705654 chr12:123083508 T/C cg23029597 chr12:123009494 RSRC2 -0.29 -4.75 -0.39 5.43e-6 Body mass index; TGCT cis rs6665290 0.594 rs17592479 chr1:227173892 T/A cg10327440 chr1:227177885 CDC42BPA -0.92 -15.37 -0.81 1.66e-30 Myeloid white cell count; TGCT cis rs453301 0.653 rs7853 chr8:8890814 A/G cg15556689 chr8:8085844 FLJ10661 0.79 7.34 0.55 2.42e-11 Joint mobility (Beighton score); TGCT cis rs9303401 0.659 rs17222621 chr17:56695923 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs4950928 0.823 rs7541061 chr1:203163367 G/T cg17014757 chr1:203156097 CHI3L1 0.45 5.39 0.44 3.45e-7 YKL-40 levels; TGCT cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs6429082 0.715 rs2131924 chr1:235580928 G/A cg26050004 chr1:235667680 B3GALNT2 -0.56 -4.9 -0.4 2.97e-6 Adiposity; TGCT cis rs28386778 0.897 rs2665833 chr17:61906846 T/C cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs1451375 1.000 rs1966839 chr7:50627101 T/C cg18232548 chr7:50535776 DDC 0.4 6.26 0.49 5.69e-9 Malaria; TGCT cis rs11577318 0.537 rs12030833 chr1:26689220 A/G cg15090202 chr1:26687087 NA 0.58 4.49 0.37 1.64e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2304725 0.526 rs1601366 chr3:10829706 G/A cg15914589 chr3:10206523 IRAK2 0.47 4.48 0.37 1.66e-5 Pulmonary function in asthmatics; TGCT cis rs7208859 0.673 rs11654331 chr17:29165017 A/G cg18442181 chr17:29233375 C17orf42 -0.79 -4.71 -0.39 6.66e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11190604 0.767 rs4919459 chr10:102200371 C/T cg23241863 chr10:102295624 HIF1AN 0.64 4.8 0.4 4.42e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2228479 0.681 rs8044906 chr16:89969603 T/C cg06558623 chr16:89946397 TCF25 0.4 5.01 0.41 1.8e-6 Skin colour saturation; TGCT cis rs8017423 0.935 rs11624246 chr14:90734826 A/G cg04374321 chr14:90722782 PSMC1 -0.75 -7.32 -0.55 2.75e-11 Mortality in heart failure; TGCT cis rs12410462 0.502 rs77615958 chr1:227806083 T/C cg23173402 chr1:227635558 NA 0.69 4.55 0.38 1.24e-5 Major depressive disorder; TGCT cis rs2334880 0.587 rs8058188 chr16:71675136 G/A cg06353428 chr16:71660113 MARVELD3 0.64 5.16 0.42 9.54e-7 Malaria; TGCT cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg26531700 chr6:26746687 NA 0.5 4.56 0.38 1.21e-5 Intelligence (multi-trait analysis); TGCT cis rs6981523 0.553 rs11783890 chr8:11056388 T/C cg21775007 chr8:11205619 TDH -0.5 -4.65 -0.39 8.26e-6 Neuroticism; TGCT cis rs7226408 0.901 rs1013833 chr18:34462214 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs916888 0.610 rs199454 chr17:44800110 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.58 -4.57 -0.38 1.15e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6701037 0.748 rs11585368 chr1:175135448 G/A cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT trans rs62103177 0.525 rs4799117 chr18:77756604 G/A cg05926928 chr17:57297772 GDPD1 -0.76 -6.89 -0.53 2.48e-10 Opioid sensitivity; TGCT cis rs1005277 0.579 rs2504140 chr10:38387579 T/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7523273 0.526 rs2745980 chr1:208018367 A/C cg22525895 chr1:207977042 MIR29B2 0.55 9.84 0.66 3.08e-17 Schizophrenia; TGCT cis rs909674 0.690 rs1972280 chr22:39831986 T/A cg11247378 chr22:39784982 NA -0.73 -8.55 -0.61 3.78e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs79387448 0.745 rs72993760 chr2:103151704 G/A cg09003973 chr2:102972529 NA 0.97 6.32 0.49 4.33e-9 Gut microbiota (bacterial taxa); TGCT cis rs2439831 0.681 rs2278859 chr15:43632960 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.91 6.89 0.53 2.52e-10 Lung cancer in ever smokers; TGCT cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.74 -0.39 5.78e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs9611565 0.765 rs132914 chr22:41805749 T/C cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs6840360 0.593 rs4696286 chr4:152606547 G/A cg22705602 chr4:152727874 NA -0.33 -5.5 -0.44 2.09e-7 Intelligence (multi-trait analysis); TGCT cis rs2302045 1.000 rs16843245 chr2:242032709 A/G cg04553960 chr2:241721320 KIF1A 0.71 4.8 0.4 4.56e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs2204008 0.837 rs7974888 chr12:37945215 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.8 0.57 2.22e-12 Bladder cancer; TGCT cis rs7216064 1.000 rs56393562 chr17:65933918 C/T cg12091567 chr17:66097778 LOC651250 -0.82 -6.21 -0.49 7.4e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs1577917 0.771 rs9450319 chr6:86427325 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.59 5.07 0.41 1.42e-6 Response to antipsychotic treatment; TGCT trans rs208520 0.690 rs207102 chr6:66795671 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs4689388 0.727 rs1801213 chr4:6293696 C/G cg25554036 chr4:6271136 WFS1 0.56 7.14 0.54 6.9e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs700590 0.532 rs10462335 chr5:88088204 G/A cg24804195 chr5:87968844 LOC645323 -0.49 -4.52 -0.38 1.43e-5 Educational attainment (years of education); TGCT cis rs7666738 0.830 rs28619044 chr4:98789814 G/C cg05340658 chr4:99064831 C4orf37 0.49 5.75 0.46 6.46e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9399137 0.507 rs7772031 chr6:135259734 G/A cg24558204 chr6:135376177 HBS1L -0.51 -5.05 -0.41 1.51e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs1215050 0.765 rs783947 chr4:99012943 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.99 -0.41 1.95e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6671200 0.915 rs34266846 chr1:95739748 G/A cg20701556 chr1:95698924 RWDD3 0.69 5.28 0.43 5.53e-7 Stearic acid (18:0) levels; TGCT cis rs1775715 0.674 rs2778670 chr10:32161676 G/A cg14930904 chr10:32216787 ARHGAP12 0.54 5.3 0.43 5.12e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2115630 0.791 rs2008262 chr15:85305270 C/T cg11189052 chr15:85197271 WDR73 -0.58 -4.94 -0.41 2.45e-6 P wave terminal force; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg08736216 chr1:53307985 ZYG11A -0.3 -5.99 -0.47 2.09e-8 Monocyte count; TGCT cis rs10193935 1.000 rs4494804 chr2:42395946 A/T cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2046867 0.818 rs17010204 chr3:72879099 G/A cg25664220 chr3:72788482 NA -0.52 -5.95 -0.47 2.54e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs13191362 0.507 rs2849525 chr6:163126652 A/C cg21926612 chr6:163149169 PACRG;PARK2 -0.6 -5.61 -0.45 1.23e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7208859 0.673 rs17826219 chr17:29161845 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7552404 0.628 rs4949686 chr1:76473299 G/C cg10523679 chr1:76189770 ACADM 0.85 6.88 0.53 2.56e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3015497 0.653 rs2356455 chr14:51093142 G/A cg04730355 chr14:51134070 SAV1 -0.63 -6.04 -0.48 1.65e-8 Mean platelet volume; TGCT cis rs1997103 1.000 rs9649781 chr7:55411809 A/G cg17469321 chr7:55412551 NA 0.61 5.96 0.47 2.42e-8 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7267979 1.000 rs397119 chr20:25440187 C/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10791097 0.694 rs7926167 chr11:130745045 T/C cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10089 0.953 rs2190797 chr5:127352875 C/A cg19767477 chr5:127420684 SLC12A2 -0.42 -4.44 -0.37 2e-5 Ileal carcinoids; TGCT cis rs7226408 0.857 rs72887048 chr18:34483420 C/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT trans rs3780486 0.718 rs73645257 chr9:33132354 C/T cg20290983 chr6:43655470 MRPS18A 0.98 7.16 0.54 6.38e-11 IgG glycosylation; TGCT trans rs28595532 0.800 rs67686161 chr4:119336720 C/T cg26518628 chr1:97050305 NA -0.56 -6.79 -0.52 4.19e-10 Cannabis dependence symptom count; TGCT cis rs798554 1.000 rs798562 chr7:2757938 C/T cg04166393 chr7:2884313 GNA12 0.6 4.44 0.37 1.97e-5 Height; TGCT cis rs4727027 1.000 rs4727027 chr7:148869277 C/T cg23583168 chr7:148888333 NA -0.73 -9.68 -0.66 7.47e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs11722228 0.522 rs73212880 chr4:10115692 T/A cg26043149 chr18:55253948 FECH 1.14 11.82 0.73 4.58e-22 Gout;Urate levels;Serum uric acid levels; TGCT cis rs7726839 0.526 rs11960159 chr5:568685 C/T cg09021430 chr5:549028 NA -0.42 -5.79 -0.46 5.31e-8 Obesity-related traits; TGCT cis rs7086627 0.515 rs1870147 chr10:82212541 A/T cg00277334 chr10:82204260 NA -0.55 -8.42 -0.6 7.84e-14 Post bronchodilator FEV1; TGCT cis rs1023500 0.551 rs61665536 chr22:42512613 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Schizophrenia; TGCT cis rs9325144 0.647 rs17518186 chr12:38883665 T/C cg26384229 chr12:38710491 ALG10B -0.61 -5.66 -0.45 1.01e-7 Morning vs. evening chronotype; TGCT cis rs4988958 0.565 rs3755265 chr2:103052816 C/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs9486719 0.857 rs2971606 chr6:97043025 C/G cg06623918 chr6:96969491 KIAA0776 -1.04 -10.25 -0.68 3.11e-18 Migraine;Coronary artery disease; TGCT cis rs6988636 1.000 rs10505430 chr8:124191933 A/G cg22384356 chr8:124195192 FAM83A 0.42 5.54 0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs2721195 0.967 rs748195 chr8:145682514 T/C cg17328964 chr8:145687451 CYHR1 -0.54 -8.46 -0.6 6.35e-14 Age at first birth; TGCT cis rs7267979 0.966 rs2257712 chr20:25264910 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 0.966 rs2500417 chr20:25383287 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2404602 0.716 rs2404737 chr15:76872217 T/G cg22467129 chr15:76604101 ETFA -0.44 -5.05 -0.41 1.51e-6 Blood metabolite levels; TGCT cis rs2486012 1.000 rs2485990 chr1:44396790 G/A cg12908607 chr1:44402522 ARTN 0.72 5.68 0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs8180040 0.966 rs11925823 chr3:47443065 C/G cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs3617 0.559 rs11915546 chr3:52866845 A/C cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6750047 0.587 rs2163454 chr2:38279170 A/C cg07380506 chr2:38303506 CYP1B1 0.57 5.07 0.41 1.42e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs4851266 1.000 rs11690335 chr2:100826429 A/G cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs9467773 0.836 rs1977198 chr6:26466225 A/C cg26531700 chr6:26746687 NA 0.54 5.07 0.41 1.43e-6 Intelligence (multi-trait analysis); TGCT cis rs2576037 0.523 rs4890705 chr18:44509758 A/G cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.71 -0.39 6.41e-6 Personality dimensions; TGCT cis rs9911578 0.967 rs57869245 chr17:57106630 A/G cg12560992 chr17:57184187 TRIM37 -0.77 -9.62 -0.65 1.03e-16 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.692 rs7350777 chr15:76985441 G/A cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs6933660 0.720 rs6936936 chr6:151753395 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.88 -9.67 -0.66 8.12e-17 Menarche (age at onset); TGCT cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg11644478 chr21:40555479 PSMG1 1.03 10.99 0.7 4.96e-20 Cognitive function; TGCT cis rs6121246 0.697 rs6088857 chr20:30226764 G/C cg13852791 chr20:30311386 BCL2L1 0.74 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin; TGCT cis rs595982 0.527 rs55706579 chr19:49382969 G/A cg15549821 chr19:49342101 PLEKHA4 -0.69 -8.61 -0.61 2.77e-14 Red cell distribution width; TGCT cis rs5769765 0.720 rs138820 chr22:50164078 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.03 0.48 1.74e-8 Schizophrenia; TGCT cis rs2013441 1.000 rs3850784 chr17:20185030 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs7811142 0.943 rs3900792 chr7:100004577 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.97 8.16 0.59 3.11e-13 Platelet count; TGCT cis rs10782582 0.593 rs4638068 chr1:76161663 G/A cg10523679 chr1:76189770 ACADM -0.69 -7.19 -0.54 5.26e-11 Daytime sleep phenotypes; TGCT cis rs6882046 0.513 rs1081158 chr5:88004616 C/T cg24804195 chr5:87968844 LOC645323 -0.61 -6.09 -0.48 1.31e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs1799949 0.930 rs8176194 chr17:41231221 A/C cg10047753 chr17:41438598 NA 0.97 9.89 0.66 2.27e-17 Menopause (age at onset); TGCT cis rs12477438 0.765 rs17708262 chr2:99696313 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.8 -8.02 -0.58 6.63e-13 Chronic sinus infection; TGCT cis rs10489202 0.608 rs7556350 chr1:168077797 C/T cg24449463 chr1:168025552 DCAF6 -0.49 -5.06 -0.41 1.49e-6 Schizophrenia; TGCT cis rs6089829 0.962 rs6062776 chr20:61663736 A/G cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs796364 1.000 rs281759 chr2:200787719 T/C cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs9362426 1.000 rs173334 chr6:88080223 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.17 0.42 8.91e-7 Depressive episodes in bipolar disorder; TGCT cis rs478304 0.654 rs10896032 chr11:65459419 C/A cg27068330 chr11:65405492 SIPA1 -0.99 -11.36 -0.71 6.13e-21 Acne (severe); TGCT cis rs4819052 0.851 rs7281263 chr21:46695606 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3087591 0.920 rs11080150 chr17:29629326 A/G cg24425628 chr17:29625626 OMG;NF1 -0.49 -7.16 -0.54 6.41e-11 Hip circumference; TGCT cis rs2932538 0.922 rs112363416 chr1:113107543 T/C cg10983938 chr1:113465962 AFARP1;SLC16A1 0.21 4.44 0.37 1.99e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs3087591 1.000 rs12939853 chr17:29455021 G/A cg24425628 chr17:29625626 OMG;NF1 0.48 7.4 0.55 1.77e-11 Hip circumference; TGCT cis rs7726839 0.507 rs72703100 chr5:614291 C/T cg16624210 chr5:671434 TPPP 0.43 4.68 0.39 7.5e-6 Obesity-related traits; TGCT trans rs17685 0.753 rs869804 chr7:75688954 A/G cg19862616 chr7:65841803 NCRNA00174 0.51 8.94 0.63 4.67e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7208859 0.623 rs216445 chr17:28933576 A/G cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2439831 0.867 rs933941 chr15:43632226 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs986417 1.000 rs1950319 chr14:61048844 T/C cg27398547 chr14:60952738 C14orf39 1.62 10.14 0.67 5.7e-18 Gut microbiota (bacterial taxa); TGCT trans rs1814175 0.645 rs28454367 chr11:50045708 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs9807989 0.811 rs11688568 chr2:102969949 C/T cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg03264133 chr6:25882463 NA 0.5 5.31 0.43 4.87e-7 Blood metabolite levels; TGCT cis rs1799949 0.930 rs2298861 chr17:41176831 G/A cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs7666738 0.830 rs10012167 chr4:99048579 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6089584 0.888 rs6089624 chr20:60619907 C/G cg06108461 chr20:60628389 TAF4 -0.69 -10.44 -0.68 1.09e-18 Body mass index; TGCT cis rs10883723 0.810 rs2296590 chr10:104262628 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9972944 0.729 rs10083870 chr17:63773272 C/T cg07283582 chr17:63770753 CCDC46 0.26 5.04 0.41 1.58e-6 Total body bone mineral density; TGCT cis rs6866344 0.661 rs72812606 chr5:178129094 A/T cg10224037 chr5:178157518 ZNF354A 0.92 7.9 0.58 1.27e-12 Neutrophil percentage of white cells; TGCT cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.91 6.75 0.52 5.09e-10 Platelet count; TGCT cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.65 6.39 0.5 3.11e-9 Menarche (age at onset); TGCT cis rs1941184 0.500 rs8096400 chr18:29017326 C/G cg14871544 chr18:29027885 DSG3 -0.43 -4.63 -0.38 9.2e-6 Parkinson's disease (age of onset); TGCT cis rs78456975 0.506 rs6756310 chr2:1549809 A/G cg01028140 chr2:1542097 TPO -0.32 -4.65 -0.39 8.2e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs17122693 1.000 rs1018039 chr14:51085793 C/T cg04730355 chr14:51134070 SAV1 1.2 9.06 0.63 2.38e-15 Cognitive performance; TGCT cis rs8014204 0.901 rs2080087 chr14:75365062 C/T cg06637938 chr14:75390232 RPS6KL1 0.78 7.42 0.55 1.58e-11 Caffeine consumption; TGCT cis rs2075371 0.966 rs2544223 chr7:133995787 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs13315871 0.790 rs9825431 chr3:58406694 G/C cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs7769051 0.615 rs12209144 chr6:133191064 A/T cg07930552 chr6:133119739 C6orf192 0.92 4.96 0.41 2.26e-6 Type 2 diabetes nephropathy; TGCT cis rs765787 0.530 rs12904265 chr15:45526713 C/T cg24006582 chr15:45444508 DUOX1 0.24 5.25 0.43 6.39e-7 Uric acid levels; TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg24503407 chr1:205819492 PM20D1 0.6 8.07 0.59 5.23e-13 Menarche (age at onset); TGCT cis rs2637266 1.000 rs1907305 chr10:78339512 C/G cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT cis rs6725041 0.819 rs11677623 chr2:213082372 A/G cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg00024416 chr22:24240387 NA -0.25 -4.76 -0.39 5.24e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17345786 0.906 rs56171035 chr3:101111108 G/C cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs1801251 0.963 rs13021246 chr2:233623111 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs6424115 0.830 rs3123554 chr1:24196401 C/T cg15997130 chr1:24165203 NA -0.86 -9.47 -0.65 2.43e-16 Immature fraction of reticulocytes; TGCT cis rs4455778 0.580 rs4270912 chr7:49112335 T/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs3796352 1.000 rs13076033 chr3:52898427 T/C cg07884673 chr3:53033167 SFMBT1 0.62 4.89 0.4 3.07e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8180040 0.932 rs11712445 chr3:47434552 T/C cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg13342137 chr4:2252803 MXD4 0.17 4.55 0.38 1.27e-5 Obesity-related traits; TGCT cis rs10751667 0.666 rs10794347 chr11:939863 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs1008375 0.966 rs3796813 chr4:17591648 A/G cg10189774 chr4:17578691 LAP3 0.67 5.88 0.47 3.63e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2276314 1.000 rs2276314 chr18:33557466 C/T cg05985134 chr18:33552581 C18orf21 -0.56 -4.93 -0.4 2.57e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs72615157 0.628 rs7801070 chr7:99847147 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.65 5.01 0.41 1.84e-6 Lung function (FEV1/FVC); TGCT cis rs9926296 0.557 rs11076618 chr16:89807705 T/C cg26513180 chr16:89883248 FANCA 0.73 7.18 0.54 5.53e-11 Vitiligo; TGCT cis rs1218582 0.596 rs4845676 chr1:154827861 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.48 -4.58 -0.38 1.13e-5 Prostate cancer; TGCT cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg23172400 chr8:95962367 TP53INP1 -0.36 -6.14 -0.48 1.04e-8 Type 2 diabetes; TGCT cis rs9611565 0.512 rs9607841 chr22:42186838 G/A cg13695892 chr22:41940480 POLR3H -0.84 -7.96 -0.58 9.47e-13 Vitiligo; TGCT cis rs6831352 0.819 rs1154401 chr4:100009738 G/C cg12011299 chr4:100065546 ADH4 0.41 5.67 0.45 9.35e-8 Alcohol dependence; TGCT cis rs881375 0.967 rs10435844 chr9:123668199 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.06 0.41 1.49e-6 Rheumatoid arthritis; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg06753367 chr22:24256600 NA -0.24 -4.48 -0.37 1.66e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.897 rs1877318 chr17:61819960 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs1124769 0.502 rs35088194 chr15:51065914 C/A cg23028286 chr15:51614521 CYP19A1 0.19 4.47 0.37 1.75e-5 Cognitive performance; TGCT cis rs6089829 0.889 rs6122348 chr20:61663921 C/T cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs112217694 1.000 rs17249293 chr4:104656784 G/A cg24090629 chr4:104641072 TACR3 -1.01 -4.96 -0.41 2.29e-6 Menarche (age at onset); TGCT cis rs11077998 0.933 rs6502121 chr17:80531314 A/G cg10255544 chr17:80519551 FOXK2 0.23 4.44 0.37 1.97e-5 Reticulocyte fraction of red cells; TGCT cis rs12220238 0.822 rs11000979 chr10:76067865 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.88 5.98 0.47 2.22e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9647570 0.582 rs2052467 chr5:167280536 C/T cg11091196 chr5:167285540 ODZ2 0.3 4.51 0.38 1.5e-5 Menarche (age at onset); TGCT cis rs3748682 0.861 rs12563037 chr1:38258644 C/G cg04496824 chr1:38276835 MTF1 -0.21 -4.68 -0.39 7.5e-6 Hypothyroidism; TGCT cis rs6969780 0.632 rs11762730 chr7:27190398 A/C cg04321618 chr7:27170880 HOXA4 -0.44 -5.05 -0.41 1.55e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6905628 1 rs6905628 chr6:90344869 C/G cg23505970 chr6:90529759 MDN1 0.66 5.26 0.43 6e-7 Coronary artery disease; TGCT cis rs2964802 0.505 rs11957751 chr5:10819973 A/G cg14521931 chr5:10832172 NA 0.27 4.55 0.38 1.29e-5 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs3784262 0.669 rs4646554 chr15:58355437 A/G cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7681440 0.838 rs1348224 chr4:90761946 G/A cg20003494 chr4:90757398 SNCA -0.62 -5.98 -0.47 2.24e-8 Dementia with Lewy bodies; TGCT cis rs514406 0.825 rs6695819 chr1:53223366 T/C cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.42e-13 Monocyte count; TGCT cis rs9916302 0.706 rs8182252 chr17:37727950 T/C cg03321784 chr17:37729644 NA -0.43 -4.7 -0.39 6.72e-6 Glomerular filtration rate (creatinine); TGCT cis rs4975709 0.569 rs1684965 chr5:1865248 A/G cg14773178 chr5:1868261 NA 0.32 5.58 0.45 1.43e-7 Cardiovascular disease risk factors; TGCT cis rs7582180 0.629 rs12620139 chr2:100943446 A/G cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs4285028 0.747 rs1127412 chr3:121414061 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.28 -0.55 3.36e-11 Multiple sclerosis; TGCT cis rs10256972 0.642 rs6961424 chr7:1004113 T/C cg18664915 chr7:1043861 C7orf50 -0.27 -4.86 -0.4 3.5e-6 Longevity;Endometriosis; TGCT cis rs17401966 0.838 rs4846209 chr1:10322054 G/A cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs1008375 0.866 rs2109518 chr4:17572162 G/A cg16339924 chr4:17578868 LAP3 0.83 7.27 0.55 3.54e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs492146 0.819 rs612483 chr6:52839958 C/T cg06706454 chr6:52930286 FBXO9 0.51 4.71 0.39 6.54e-6 Epilepsy (remission after treatment); TGCT cis rs7582180 0.676 rs6542940 chr2:100982144 A/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.34e-6 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.809 rs12152763 chr5:93405509 T/A cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs7474896 0.559 rs1208560 chr10:38221618 A/T cg13720705 chr10:37990370 NA -0.34 -4.58 -0.38 1.13e-5 Obesity (extreme); TGCT cis rs4295623 0.559 rs2409836 chr8:11689228 T/G cg21775007 chr8:11205619 TDH 0.57 5.02 0.41 1.78e-6 Morning vs. evening chronotype; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg06873352 chr17:61820015 STRADA 0.58 6.43 0.5 2.55e-9 Prudent dietary pattern; TGCT cis rs2334880 0.602 rs12444212 chr16:71437689 T/C cg06353428 chr16:71660113 MARVELD3 -1.16 -7.04 -0.53 1.18e-10 Malaria; TGCT cis rs10504229 0.639 rs112926738 chr8:58054939 A/G cg02725872 chr8:58115012 NA -0.38 -4.79 -0.39 4.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs362272 0.545 rs2749783 chr4:3326098 A/C cg22655196 chr4:3374909 RGS12 0.24 4.97 0.41 2.13e-6 Serum sulfate level; TGCT cis rs3617 0.573 rs4687680 chr3:52907372 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.52 5.05 0.41 1.55e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg11890956 chr21:40555474 PSMG1 -0.79 -6.98 -0.53 1.58e-10 Cognitive function; TGCT cis rs7917772 0.532 rs10748829 chr10:104527244 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.58 -4.75 -0.39 5.56e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6840360 1.000 rs3749561 chr4:152610117 C/T cg22705602 chr4:152727874 NA 0.25 4.45 0.37 1.92e-5 Intelligence (multi-trait analysis); TGCT cis rs6964587 0.967 rs7788092 chr7:91646198 C/T cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs1153858 1.000 rs3759899 chr15:45655903 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs71435601 0.628 rs559318 chr2:21381490 C/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs11122272 0.735 rs2437147 chr1:231516756 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs4851254 0.618 rs7596359 chr2:100665274 T/G cg22139774 chr2:100720529 AFF3 -0.44 -4.69 -0.39 7.04e-6 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg18654377 chr3:49208889 KLHDC8B -0.39 -5.04 -0.41 1.6e-6 Menarche (age at onset); TGCT cis rs3796352 1.000 rs3806692 chr3:53080987 C/G cg15956490 chr3:53032818 SFMBT1 0.53 6.21 0.49 7.31e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg16145915 chr7:1198662 ZFAND2A -0.6 -8.5 -0.61 5.11e-14 Longevity;Endometriosis; TGCT cis rs9916302 0.904 rs7223438 chr17:37521355 T/C cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs7809950 0.599 rs2237658 chr7:106837866 T/G cg23024343 chr7:107201750 COG5 -0.37 -5.27 -0.43 5.84e-7 Coronary artery disease; TGCT cis rs9393692 0.905 rs34916901 chr6:26286149 G/T cg00631329 chr6:26305371 NA -0.44 -6.59 -0.51 1.15e-9 Educational attainment; TGCT cis rs2046867 0.908 rs62251650 chr3:72809823 T/C cg25664220 chr3:72788482 NA -0.57 -7.16 -0.54 6.2e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs13188771 0.651 rs3912803 chr5:100881268 T/G cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT trans rs7819412 0.594 rs7460507 chr8:10969075 C/T cg15556689 chr8:8085844 FLJ10661 -0.7 -6.86 -0.52 2.97e-10 Triglycerides; TGCT cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg07061783 chr6:25882402 NA -0.43 -4.72 -0.39 6.37e-6 Height; TGCT cis rs2956278 0.717 rs2956284 chr12:84690282 A/G cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs7267979 1.000 rs404394 chr20:25447896 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7659604 0.539 rs2063165 chr4:122750005 A/G cg06713675 chr4:122721982 EXOSC9 -0.68 -9.21 -0.64 1.05e-15 Type 2 diabetes; TGCT cis rs9818758 0.556 rs13086240 chr3:49001409 G/A cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7769051 1.000 rs6910639 chr6:133120553 A/G cg07930552 chr6:133119739 C6orf192 0.94 5.04 0.41 1.6e-6 Type 2 diabetes nephropathy; TGCT cis rs709400 0.663 rs7158822 chr14:103887868 C/T cg26031613 chr14:104095156 KLC1 0.84 9.43 0.65 2.98e-16 Body mass index; TGCT cis rs6540559 0.740 rs2064163 chr1:210048819 G/T cg23283495 chr1:209979779 IRF6 0.7 5.71 0.46 7.88e-8 Cleft lip with or without cleft palate; TGCT cis rs2932538 0.922 rs12138335 chr1:113122760 T/C cg10983938 chr1:113465962 AFARP1;SLC16A1 0.21 4.44 0.37 1.99e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs11190604 1.000 rs9420782 chr10:102235015 G/A cg23241863 chr10:102295624 HIF1AN 0.63 4.97 0.41 2.2e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7843479 0.932 rs68023663 chr8:21794379 T/C cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs801193 1.000 rs7789184 chr7:66210195 A/T cg18876405 chr7:65276391 NA 0.36 5.36 0.43 3.97e-7 Aortic root size; TGCT cis rs8038465 0.622 rs2509 chr15:73859488 A/T cg15420318 chr15:73925796 NPTN -0.59 -6.03 -0.48 1.75e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.830 rs4699331 chr4:99059816 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs651907 0.557 rs59596156 chr3:101394217 C/T cg12386194 chr3:101231763 SENP7 0.52 5.1 0.42 1.24e-6 Colorectal cancer; TGCT cis rs4975709 0.589 rs4975707 chr5:1864028 C/T cg04156016 chr5:1868137 NA 0.34 4.89 0.4 3.06e-6 Cardiovascular disease risk factors; TGCT cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg15691649 chr6:25882328 NA 0.48 5.55 0.45 1.63e-7 Blood metabolite levels; TGCT cis rs6121246 0.738 rs2376996 chr20:30316667 T/A cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg06873352 chr17:61820015 STRADA 0.56 6.12 0.48 1.15e-8 Prudent dietary pattern; TGCT cis rs3806843 1.000 rs6885319 chr5:140200611 A/C cg19875535 chr5:140030758 IK 0.35 5.86 0.47 3.93e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg02487422 chr3:49467188 NICN1 0.5 4.55 0.38 1.24e-5 Parkinson's disease; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg15242686 chr22:24348715 GSTTP1 0.5 7.4 0.55 1.78e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs1814175 0.645 rs1851850 chr11:50012168 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs3091242 0.900 rs1811832 chr1:25753565 G/A cg09222892 chr1:25734099 RHCE -0.42 -6.75 -0.52 5.02e-10 Erythrocyte sedimentation rate; TGCT cis rs12765878 0.603 rs10883944 chr10:105651657 G/T cg11005552 chr10:105648138 OBFC1 -0.4 -6.19 -0.49 8.13e-9 Coronary artery disease; TGCT trans rs12339966 0.653 rs10733231 chr9:11285060 C/G cg07173112 chr1:1114698 TTLL10 -0.34 -6.84 -0.52 3.15e-10 Systolic blood pressure; TGCT cis rs5769707 0.681 rs6009803 chr22:50051007 A/G cg06623630 chr22:50017776 C22orf34 -0.26 -4.51 -0.38 1.45e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs56104184 0.775 rs73061699 chr19:49400511 T/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4727027 0.899 rs11771339 chr7:148854132 A/T cg23583168 chr7:148888333 NA -0.77 -10.05 -0.67 9.78e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs10193935 0.901 rs10200000 chr2:42442212 A/G cg27598129 chr2:42591480 NA -0.37 -5.09 -0.42 1.3e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs4253772 0.591 rs6008362 chr22:46652737 G/A cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs1218582 0.774 rs4845683 chr1:154877407 T/C cg24250549 chr1:154909240 PMVK 0.56 5.42 0.44 2.92e-7 Prostate cancer; TGCT cis rs7666738 0.753 rs28463863 chr4:98844444 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.57 0.56 7.47e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9527 0.615 rs10883810 chr10:104727224 A/C cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs1008375 1.000 rs1121090 chr4:17676437 C/G cg16339924 chr4:17578868 LAP3 0.53 4.62 0.38 9.58e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs981844 0.683 rs1105496 chr4:154756755 T/C cg14289246 chr4:154710475 SFRP2 -0.96 -8.97 -0.63 3.91e-15 Response to statins (LDL cholesterol change); TGCT cis rs7584330 0.737 rs6431539 chr2:238360708 G/T cg14458575 chr2:238380390 NA 0.47 7.39 0.55 1.9e-11 Prostate cancer; TGCT cis rs12360000 0.864 rs11250842 chr10:1904284 A/C cg26364871 chr10:1889757 NA 0.41 4.63 0.38 9.26e-6 Metabolite levels (Dihydroxy docosatrienoic acid); TGCT cis rs931127 0.658 rs4930305 chr11:65464000 A/G cg27068330 chr11:65405492 SIPA1 0.64 6.18 0.49 8.27e-9 Systemic lupus erythematosus; TGCT cis rs790110 1.000 rs2668336 chr3:122384469 T/A cg07366462 chr3:123162899 ADCY5 0.42 4.71 0.39 6.54e-6 Acoustic startle blink response; TGCT cis rs9796 0.621 rs2899013 chr15:41492283 G/T cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.12 -0.54 7.62e-11 Menopause (age at onset); TGCT cis rs916888 0.821 rs199512 chr17:44857352 T/C cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7523273 0.606 rs2761430 chr1:207912408 G/A cg22525895 chr1:207977042 MIR29B2 0.56 9.32 0.64 5.42e-16 Schizophrenia; TGCT cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs34286592 0.929 rs1057452 chr16:29833714 A/G cg07060908 chr16:29884970 SEZ6L2 0.26 4.51 0.38 1.49e-5 Multiple sclerosis; TGCT cis rs12220898 0.749 rs4483512 chr10:50480390 G/A cg09603381 chr10:49954066 WDFY4 0.39 4.48 0.37 1.68e-5 Inflammatory biomarkers; TGCT cis rs7216064 1.000 rs7212293 chr17:65847325 A/G cg12091567 chr17:66097778 LOC651250 -0.85 -6.84 -0.52 3.14e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4819052 0.851 rs35064782 chr21:46674360 G/A cg06618935 chr21:46677482 NA -0.37 -5.54 -0.45 1.71e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs34014631 1.000 rs80080632 chr10:103710001 T/C cg22630918 chr10:102748988 C10orf2 0.42 4.78 0.39 4.86e-6 Coronary artery calcification; TGCT cis rs2762353 0.546 rs2294346 chr6:25689487 G/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.74 -0.39 5.83e-6 Blood metabolite levels; TGCT cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1580019 0.961 rs1580022 chr7:32497712 C/A cg06627557 chr7:32535165 LSM5;AVL9 0.81 7.61 0.56 5.93e-12 Cognitive ability; TGCT cis rs7617773 0.823 rs9839446 chr3:48194666 T/A cg11946769 chr3:48343235 NME6 -0.61 -5.45 -0.44 2.6e-7 Coronary artery disease; TGCT cis rs826838 0.904 rs7973992 chr12:39168233 T/C cg26384229 chr12:38710491 ALG10B 1.0 8.98 0.63 3.56e-15 Heart rate; TGCT cis rs13256369 1.000 rs7004438 chr8:8574379 C/T cg18904891 chr8:8559673 CLDN23 0.64 5.89 0.47 3.36e-8 Obesity-related traits; TGCT cis rs2933343 0.700 rs2624910 chr3:128650275 G/C cg11901034 chr3:128598214 ACAD9 -0.65 -6.08 -0.48 1.38e-8 IgG glycosylation; TGCT cis rs2050392 0.929 rs10826798 chr10:30700904 G/A cg18806716 chr10:30721971 MAP3K8 0.46 5.5 0.44 2.04e-7 Inflammatory bowel disease; TGCT cis rs7809950 1.000 rs2395883 chr7:107089670 T/C cg23024343 chr7:107201750 COG5 -0.36 -5.63 -0.45 1.12e-7 Coronary artery disease; TGCT cis rs736408 0.812 rs746694 chr3:52826620 C/T cg07507251 chr3:52567010 NT5DC2 0.45 5.99 0.47 2.1e-8 Bipolar disorder; TGCT cis rs12762955 0.528 rs10903358 chr10:1102386 G/A cg20503657 chr10:835505 NA 0.57 6.46 0.5 2.21e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs2197308 0.659 rs11181327 chr12:37903171 C/T cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs67311347 1.000 rs9857824 chr3:40459412 A/G cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs55794721 0.509 rs6699113 chr1:25777743 C/T cg10117171 chr1:25599238 RHD -0.32 -5.22 -0.42 7.32e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.76 6.5 0.5 1.8e-9 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs8135665 0.600 rs6519096 chr22:38451389 C/T cg13116946 chr22:38479732 SLC16A8 0.3 5.77 0.46 5.94e-8 Advanced age-related macular degeneration;Age-related macular degeneration; TGCT cis rs1005277 0.579 rs176886 chr10:38403974 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2046867 0.862 rs11922180 chr3:72836119 A/G cg25664220 chr3:72788482 NA 0.56 7.05 0.53 1.1e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1008375 0.966 rs6449313 chr4:17588320 A/G cg16339924 chr4:17578868 LAP3 0.77 6.62 0.51 9.84e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 0.966 rs2261790 chr20:25262789 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 1.000 rs8176296 chr17:41203591 T/C cg23758822 chr17:41437982 NA 0.75 7.03 0.53 1.22e-10 Menopause (age at onset); TGCT cis rs6748734 1.000 rs10933518 chr2:241838091 A/C cg04034577 chr2:241836375 C2orf54 -0.41 -6.31 -0.49 4.55e-9 Urinary metabolites; TGCT cis rs2663905 0.611 rs2663924 chr15:81392903 T/G cg18028999 chr15:81426610 C15orf26 -0.5 -4.66 -0.39 8.07e-6 QT interval (drug interaction); TGCT cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs116098781 chr4:119771613 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs2832191 0.729 rs2832201 chr21:30499841 A/G cg08807101 chr21:30365312 RNF160 -0.67 -6.13 -0.48 1.1e-8 Dental caries; TGCT cis rs769267 0.965 rs10419245 chr19:19383755 G/A cg03709012 chr19:19516395 GATAD2A 0.67 5.78 0.46 5.66e-8 Tonsillectomy; TGCT trans rs3780486 0.846 rs7864705 chr9:33140352 A/C cg04842962 chr6:43655489 MRPS18A 1.22 15.42 0.81 1.27e-30 IgG glycosylation; TGCT cis rs7953508 0.506 rs10859532 chr12:93960917 G/C cg18151635 chr12:93972918 NA -0.19 -4.55 -0.38 1.24e-5 Pubertal anthropometrics; TGCT cis rs10782582 0.545 rs111927462 chr1:76195422 A/G cg22875332 chr1:76189707 ACADM -0.5 -5.51 -0.44 2e-7 Daytime sleep phenotypes; TGCT cis rs807669 0.548 rs885979 chr22:19198375 T/C cg02655711 chr22:19163373 SLC25A1 0.3 5.9 0.47 3.22e-8 Metabolite levels; TGCT cis rs9894429 1.000 rs3935543 chr17:79579874 T/C cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs4455778 0.626 rs10241999 chr7:49052839 C/G cg26309511 chr7:48887640 NA -0.4 -4.86 -0.4 3.53e-6 Lung cancer in never smokers; TGCT cis rs7213347 0.780 rs1555568 chr17:2149505 T/C cg13315690 chr17:1944831 OVCA2;DPH1 -0.38 -4.69 -0.39 7.1e-6 Total body bone mineral density; TGCT cis rs6582630 0.519 rs11495700 chr12:38288240 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.29 0.55 3.15e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs10782582 0.593 rs115291524 chr1:76141811 A/G cg10523679 chr1:76189770 ACADM -0.68 -7.06 -0.54 1.03e-10 Daytime sleep phenotypes; TGCT cis rs9611565 0.918 rs6002351 chr22:41757223 C/T cg06634786 chr22:41940651 POLR3H -0.8 -7.65 -0.57 4.81e-12 Vitiligo; TGCT cis rs2887571 0.505 rs78275802 chr12:1637691 G/A cg01940102 chr12:1095972 NA 0.26 4.78 0.39 4.92e-6 Bone mineral density; TGCT cis rs7588746 0.868 rs12104649 chr2:201128832 C/T cg23649088 chr2:200775458 C2orf69 -0.33 -4.72 -0.39 6.33e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs7659604 0.539 rs72680779 chr4:122797263 C/T cg06713675 chr4:122721982 EXOSC9 -0.67 -8.91 -0.62 5.46e-15 Type 2 diabetes; TGCT trans rs10506458 1.000 rs11174759 chr12:63444363 A/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.62 -0.56 5.8e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs3931020 0.548 rs17618340 chr1:75247617 G/A cg17719053 chr1:75198211 TYW3;CRYZ 0.47 4.9 0.4 2.94e-6 Resistin levels; TGCT cis rs72781680 0.950 rs72796402 chr2:24180104 A/G cg08917208 chr2:24149416 ATAD2B 0.9 5.45 0.44 2.62e-7 Lymphocyte counts; TGCT cis rs801193 0.761 rs2659888 chr7:66230171 T/G cg18876405 chr7:65276391 NA 0.35 5.2 0.42 8.09e-7 Aortic root size; TGCT cis rs3087591 0.922 rs12950506 chr17:29598392 A/G cg24425628 chr17:29625626 OMG;NF1 0.47 7.21 0.54 4.8e-11 Hip circumference; TGCT cis rs17122693 1.000 rs72679576 chr14:51090881 G/A cg04730355 chr14:51134070 SAV1 1.24 8.74 0.62 1.38e-14 Cognitive performance; TGCT cis rs739496 0.843 rs848132 chr12:111989979 C/A cg10833066 chr12:111807467 FAM109A 0.37 4.96 0.41 2.31e-6 Platelet count; TGCT cis rs10832963 1.000 rs2084220 chr11:18656932 C/T cg20219074 chr11:18656078 SPTY2D1 0.98 9.86 0.66 2.75e-17 Breast cancer; TGCT cis rs7647973 0.626 rs7649428 chr3:49868876 A/T cg05785598 chr3:49045655 WDR6 -0.43 -5.38 -0.43 3.63e-7 Menarche (age at onset); TGCT cis rs36051895 0.625 rs12340333 chr9:5176215 C/G cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.2e-20 Pediatric autoimmune diseases; TGCT cis rs1218582 0.741 rs2335407 chr1:154843347 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.65 6.36 0.5 3.55e-9 Prostate cancer; TGCT cis rs1801251 1.000 rs13013142 chr2:233600606 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs7829975 0.840 rs572366 chr8:8578794 A/T cg06636001 chr8:8085503 FLJ10661 0.6 4.92 0.4 2.7e-6 Mood instability; TGCT cis rs68170813 0.599 rs12533516 chr7:106937135 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs9916302 0.904 rs9892055 chr17:37510402 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs9926296 0.512 rs11076626 chr16:89865103 T/A cg04287289 chr16:89883240 FANCA 0.93 12.26 0.74 4.13e-23 Vitiligo; TGCT cis rs9486719 0.948 rs11152970 chr6:96909077 A/G cg06623918 chr6:96969491 KIAA0776 -0.98 -8.77 -0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs7552404 0.727 rs12122939 chr1:76276353 T/C cg22875332 chr1:76189707 ACADM 0.64 6.9 0.53 2.32e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1799949 0.965 rs4793233 chr17:41435437 G/C cg10047753 chr17:41438598 NA 0.94 9.17 0.64 1.28e-15 Menopause (age at onset); TGCT cis rs4642101 0.628 rs1003080 chr3:12811628 C/T cg04715183 chr3:11886989 C3orf31 0.18 4.51 0.38 1.51e-5 QRS complex (12-leadsum); TGCT cis rs10927875 0.800 rs1627145 chr1:16328116 C/T cg14742211 chr1:16348397 CLCNKA 0.19 4.45 0.37 1.88e-5 Dilated cardiomyopathy; TGCT cis rs10089 1.000 rs4835941 chr5:127430905 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.79 7.6 0.56 6.47e-12 Ileal carcinoids; TGCT cis rs3125734 0.608 rs7905731 chr10:64018472 T/C cg09941381 chr10:64027924 RTKN2 -0.36 -5.48 -0.44 2.26e-7 Rheumatoid arthritis; TGCT cis rs350251 0.899 rs350275 chr16:12233099 G/C cg02910054 chr16:12241554 SNX29 0.33 4.57 0.38 1.18e-5 Intelligence (multi-trait analysis); TGCT cis rs4072705 0.967 rs10760369 chr9:127397400 A/G cg13476313 chr9:127244764 NR5A1 0.29 4.72 0.39 6.13e-6 Menarche (age at onset); TGCT cis rs4233949 0.868 rs7607093 chr2:54659174 G/T cg14634210 chr2:54682758 SPTBN1 -0.58 -4.87 -0.4 3.31e-6 Bone mineral density; TGCT cis rs3816788 0.792 rs7013323 chr8:21869024 C/G cg17168535 chr8:21777572 XPO7 0.77 7.84 0.58 1.77e-12 Lung cancer in ever smokers; TGCT cis rs4819052 0.851 rs7279011 chr21:46655995 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.69 6.07 0.48 1.41e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6714710 0.603 rs34502870 chr2:98405929 A/G cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs10751667 0.666 rs12295141 chr11:947065 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.29 -0.6 1.6e-13 Alzheimer's disease (late onset); TGCT cis rs13191362 0.935 rs34035978 chr6:163165336 G/C cg21926612 chr6:163149169 PACRG;PARK2 0.88 7.8 0.57 2.15e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6089829 0.962 rs6011548 chr20:61666063 C/T cg03213289 chr20:61660250 NA 0.7 10.11 0.67 6.94e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs6815814 0.950 rs5743571 chr4:38805489 C/T cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs7584330 0.784 rs6724766 chr2:238413600 A/G cg16989719 chr2:238392110 NA -0.28 -4.78 -0.39 4.8e-6 Prostate cancer; TGCT cis rs2439831 1.000 rs1814538 chr15:43759774 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.93 -8.02 -0.58 6.8e-13 Lung cancer in ever smokers; TGCT cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs3091242 0.933 rs11249250 chr1:25767609 G/A cg23205692 chr1:25664452 TMEM50A 0.49 5.17 0.42 9e-7 Erythrocyte sedimentation rate; TGCT cis rs4595586 0.545 rs7958118 chr12:39376685 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg18402987 chr7:1209562 NA 0.74 6.37 0.5 3.28e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3020736 0.500 rs7364293 chr22:42506370 C/T cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs5769765 1.000 rs764813 chr22:50286172 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs7086627 0.515 rs10887901 chr10:82210581 G/A cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs9527 0.590 rs1046411 chr10:104837816 G/A cg15744005 chr10:104629667 AS3MT -0.38 -4.52 -0.38 1.42e-5 Arsenic metabolism; TGCT cis rs9948 0.529 rs62156222 chr2:97410988 C/A cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs700590 0.723 rs304159 chr5:88138042 C/T cg22951263 chr5:87985283 NA 0.57 5.19 0.42 8.52e-7 Educational attainment (years of education); TGCT cis rs6714710 0.580 rs11692470 chr2:98520564 T/C cg26665480 chr2:98280029 ACTR1B 0.64 6.06 0.48 1.48e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7916852 0.867 rs7091158 chr10:28387300 A/G cg15286905 chr10:27530250 ACBD5 -0.45 -4.46 -0.37 1.78e-5 Glaucoma (primary open-angle); TGCT cis rs10206020 0.921 rs11884956 chr2:1566426 A/G cg01028140 chr2:1542097 TPO -0.34 -5.32 -0.43 4.61e-7 IgG glycosylation; TGCT cis rs4665809 0.941 rs1470096 chr2:26311482 T/C cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs17108533 0.588 rs12886796 chr14:71301556 A/G cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs5750830 0.649 rs5750813 chr22:39795228 G/C cg11247378 chr22:39784982 NA -0.74 -9.62 -0.65 1.08e-16 Intelligence (multi-trait analysis); TGCT cis rs367615 0.918 rs17161889 chr5:108855251 A/G cg17395555 chr5:108820864 NA -0.3 -4.85 -0.4 3.57e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs735396 0.694 rs2264750 chr12:121450165 C/T cg15155738 chr12:121454335 C12orf43 0.55 4.76 0.39 5.4e-6 N-glycan levels; TGCT cis rs6484504 0.576 rs208083 chr11:31196880 C/T cg26647111 chr11:31128758 NA -0.32 -4.47 -0.37 1.74e-5 Red blood cell count; TGCT cis rs8014204 0.836 rs7150254 chr14:75299101 G/A cg06637938 chr14:75390232 RPS6KL1 0.7 6.74 0.52 5.37e-10 Caffeine consumption; TGCT cis rs9325144 0.581 rs2730929 chr12:38942739 T/C cg26384229 chr12:38710491 ALG10B -0.65 -6.51 -0.5 1.69e-9 Morning vs. evening chronotype; TGCT cis rs1799949 1.000 rs2037076 chr17:41305883 G/A cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs2050392 0.931 rs2265189 chr10:30689316 C/T cg18806716 chr10:30721971 MAP3K8 0.42 4.85 0.4 3.65e-6 Inflammatory bowel disease; TGCT cis rs9611565 0.729 rs137831 chr22:41903813 A/C cg13695892 chr22:41940480 POLR3H -0.88 -8.89 -0.62 6.1e-15 Vitiligo; TGCT trans rs797680 0.822 rs6541401 chr1:93738948 G/A cg27528825 chr2:159282178 CCDC148 0.34 6.71 0.52 6.32e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs4975616 0.836 rs13178866 chr5:1323212 C/T cg06550200 chr5:1325588 CLPTM1L -0.3 -4.6 -0.38 1.04e-5 Lung cancer; TGCT cis rs704795 0.805 rs1728926 chr2:27612937 A/G cg12000995 chr2:27665139 KRTCAP3 -0.37 -4.58 -0.38 1.11e-5 Menopause (age at onset); TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg14851468 chr5:179071604 C5orf60 0.22 4.54 0.38 1.32e-5 Lung cancer; TGCT cis rs12477438 1.000 rs6732980 chr2:99921613 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -6.3 -0.49 4.62e-9 Chronic sinus infection; TGCT cis rs7086627 0.515 rs11202959 chr10:82209672 A/G cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs3784262 0.528 rs4646589 chr15:58303165 C/T cg12031962 chr15:58353849 ALDH1A2 0.38 5.43 0.44 2.8e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2243480 1.000 rs35058610 chr7:65390925 G/A cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT trans rs208520 0.690 rs6929762 chr6:66709277 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs11122272 0.735 rs2808586 chr1:231515559 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs17206232 0.534 rs13165244 chr5:64693002 T/C cg09571848 chr5:64330935 NA -0.31 -4.46 -0.37 1.82e-5 Schizophrenia; TGCT cis rs62103177 0.810 rs62103194 chr18:77629482 G/A cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs4273100 0.646 rs4924990 chr17:19294824 G/T cg03910582 chr17:19030146 GRAPL -0.54 -5.44 -0.44 2.73e-7 Schizophrenia; TGCT cis rs6121246 0.542 rs2376990 chr20:30238744 G/A cg21427119 chr20:30132790 HM13 -0.35 -4.72 -0.39 6.19e-6 Mean corpuscular hemoglobin; TGCT trans rs1005277 0.579 rs2472174 chr10:38375382 A/G cg27523141 chr10:43048294 ZNF37B 0.73 8.4 0.6 8.55e-14 Extrinsic epigenetic age acceleration; TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs11098499 0.954 rs6820115 chr4:120398182 T/C cg09307838 chr4:120376055 NA 0.63 6.2 0.49 7.68e-9 Corneal astigmatism; TGCT cis rs910316 0.737 rs175065 chr14:75494983 T/C cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.38e-7 Height; TGCT cis rs13326165 0.616 rs82825 chr3:52471942 G/A cg07884673 chr3:53033167 SFMBT1 -0.39 -4.7 -0.39 6.74e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs422249 0.512 rs174574 chr11:61600342 A/C cg01500311 chr11:61656094 FADS3 0.32 5.69 0.46 8.54e-8 Trans fatty acid levels; TGCT cis rs2836974 0.623 rs34240248 chr21:40685239 A/G cg11644478 chr21:40555479 PSMG1 -0.6 -5.3 -0.43 5.09e-7 Cognitive function; TGCT cis rs4862750 0.832 rs6836076 chr4:187899660 A/C cg03452623 chr4:187889614 NA -0.34 -4.94 -0.41 2.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9905704 0.624 rs34718875 chr17:57072461 G/A cg12560992 chr17:57184187 TRIM37 0.6 5.52 0.44 1.93e-7 Testicular germ cell tumor; TGCT cis rs7216064 0.601 rs35453056 chr17:66039668 A/G cg12091567 chr17:66097778 LOC651250 1.08 8.86 0.62 7.21e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs56399783 0.901 rs73049341 chr7:2812255 G/C cg19731401 chr7:2775893 GNA12 0.35 4.91 0.4 2.76e-6 Childhood ear infection; TGCT cis rs344364 0.511 rs2982433 chr16:1954508 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.4 -4.73 -0.39 6.05e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7618915 0.547 rs3774365 chr3:52642487 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg03264133 chr6:25882463 NA -0.65 -5.88 -0.47 3.48e-8 Intelligence (multi-trait analysis); TGCT cis rs8017423 1.000 rs4900028 chr14:90685594 C/T cg04374321 chr14:90722782 PSMC1 0.77 7.93 0.58 1.12e-12 Mortality in heart failure; TGCT cis rs28595532 0.920 rs17259284 chr4:119779298 T/C cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg11141652 chr22:24348549 GSTTP1 -0.33 -4.58 -0.38 1.1e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11690935 0.632 rs6737308 chr2:172872042 G/A cg13550731 chr2:172543902 DYNC1I2 0.6 5.23 0.43 7e-7 Schizophrenia; TGCT cis rs939658 0.805 rs35318825 chr15:79447098 C/A cg17916960 chr15:79447300 NA -0.51 -7.83 -0.58 1.84e-12 Refractive error; TGCT cis rs2439831 0.867 rs2245715 chr15:43818052 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.98 7.56 0.56 7.97e-12 Lung cancer in ever smokers; TGCT cis rs899997 0.862 rs4887074 chr15:78952110 G/C cg00061860 chr15:78953028 NA -0.33 -5.95 -0.47 2.5e-8 Coronary artery disease or large artery stroke; TGCT cis rs6121246 0.909 rs8126355 chr20:30332660 C/T cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs2016266 0.784 rs10747666 chr12:53716836 G/A cg16917193 chr12:54089295 NA 0.67 5.2 0.42 8e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs1401999 1.000 rs6767013 chr3:183680102 G/A cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs34779708 0.931 rs59418206 chr10:35331624 G/A cg04310649 chr10:35416472 CREM -0.53 -4.79 -0.4 4.64e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs9902453 0.967 rs9913074 chr17:28481199 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs11948739 0.573 rs12332505 chr5:130337348 T/G cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Pediatric bone mineral content (hip); TGCT cis rs10883723 0.810 rs10883729 chr10:104273943 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs8070128 0.600 rs8071238 chr17:17900990 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 7.87 0.58 1.5e-12 Total body bone mineral density; TGCT cis rs6430585 0.528 rs309142 chr2:136715324 T/C cg07169764 chr2:136633963 MCM6 1.22 11.95 0.73 2.26e-22 Corneal structure; TGCT cis rs4930561 0.739 rs7118045 chr11:67978734 C/G cg04465784 chr11:67976953 SUV420H1 -0.38 -5.5 -0.44 2.07e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs8032315 0.965 rs8027450 chr15:91418394 C/T cg04510874 chr15:91427884 FES 0.5 5.62 0.45 1.2e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs8180040 1.000 rs11714294 chr3:47339723 G/A cg27129171 chr3:47204927 SETD2 -0.7 -8.55 -0.61 3.88e-14 Colorectal cancer; TGCT cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg15659132 chr6:26577336 NA 0.86 10.93 0.7 6.8e-20 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.569 rs6556834 chr5:93123067 C/T cg21475434 chr5:93447410 FAM172A -0.6 -4.9 -0.4 2.92e-6 Diabetic retinopathy; TGCT cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg03161606 chr19:29218774 NA 0.62 6.0 0.47 2e-8 Methadone dose in opioid dependence; TGCT cis rs17534004 1.000 rs17534137 chr13:31471920 G/A cg13251181 chr13:31481184 C13orf33 0.36 4.99 0.41 1.97e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT trans rs4576506 0.826 rs1929103 chr9:31503499 T/G cg11445191 chr5:140227765 PCDHA6;PCDHA2;PCDHA1;PCDHA7;PCDHA5;PCDHA9;PCDHA3;PCDHA4;PCDHA8 0.98 6.69 0.51 6.76e-10 Psychosis and Alzheimer's disease; TGCT cis rs6725041 0.547 rs59096325 chr2:213203853 C/T cg20637307 chr2:213403960 ERBB4 -0.53 -4.5 -0.37 1.52e-5 QT interval (ambient particulate matter interaction); TGCT cis rs4455778 0.579 rs4563839 chr7:49076344 T/A cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.07e-9 Lung cancer in never smokers; TGCT cis rs1443512 0.812 rs1867299 chr12:54329975 T/C cg17708016 chr12:54321992 NA 0.57 4.67 0.39 7.84e-6 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); TGCT cis rs61990749 0.597 rs9788540 chr14:78132172 G/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.67 -4.7 -0.39 6.93e-6 Fibroblast growth factor basic levels; TGCT cis rs3733585 0.673 rs4292332 chr4:9953830 C/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs55823223 0.648 rs936393 chr17:73847613 A/G cg10935138 chr17:73851978 WBP2 1.0 10.11 0.67 6.79e-18 Psoriasis; TGCT cis rs3796352 0.892 rs35076015 chr3:53026366 C/T cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg13409248 chr3:40428643 ENTPD3 0.57 4.58 0.38 1.13e-5 Renal cell carcinoma; TGCT cis rs2982552 1.000 rs3020304 chr6:152064464 C/T cg22157087 chr6:152012887 ESR1 0.19 4.57 0.38 1.15e-5 Bone properties (heel); TGCT cis rs2862064 1.000 rs2055429 chr5:156455113 C/G cg12943317 chr5:156479607 HAVCR1 -0.48 -5.94 -0.47 2.64e-8 Platelet count; TGCT cis rs11719291 0.584 rs13080725 chr3:49076092 G/A cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 Cognitive function; TGCT cis rs11148252 1.000 rs11148252 chr13:53009048 C/T cg00495681 chr13:53174319 NA 0.46 4.51 0.38 1.49e-5 Lewy body disease; TGCT cis rs12950390 0.853 rs11079790 chr17:45853626 G/A cg06532163 chr17:45867833 NA 0.33 5.16 0.42 9.7e-7 IgG glycosylation; TGCT cis rs116095464 0.558 rs9312979 chr5:222057 A/C cg12570787 chr5:219185 SDHA;CCDC127 0.71 4.75 0.39 5.44e-6 Breast cancer; TGCT cis rs9457247 0.967 rs2757054 chr6:167380501 A/G cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.08e-6 Crohn's disease; TGCT cis rs6500602 0.893 rs4786489 chr16:4485527 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.13 0.42 1.08e-6 Schizophrenia; TGCT cis rs2439831 1.000 rs2467736 chr15:43784917 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.51 0.44 1.95e-7 Lung cancer in ever smokers; TGCT cis rs7833790 0.929 rs28464834 chr8:82797356 A/T cg17211192 chr8:82754475 SNX16 0.95 7.32 0.55 2.79e-11 Diastolic blood pressure; TGCT cis rs73198271 0.920 rs11781542 chr8:8617181 G/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.79 -0.39 4.72e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7267979 0.780 rs2500413 chr20:25241155 T/C cg03522245 chr20:25566470 NINL 0.48 4.59 0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6770219 0.516 rs7635602 chr3:186134939 G/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs4665809 0.590 rs7579504 chr2:26439995 T/C cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs7017914 0.905 rs2732102 chr8:71922872 C/T cg23757474 chr8:71581111 LACTB2;XKR9 0.55 5.17 0.42 9.24e-7 Bone mineral density; TGCT cis rs12136530 0.593 rs12404362 chr1:19739958 A/G cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs79149102 0.579 rs7172065 chr15:75321910 C/T cg09165964 chr15:75287851 SCAMP5 -1.03 -5.26 -0.43 6.24e-7 Lung cancer; TGCT cis rs6089829 1.000 rs6089829 chr20:61669036 C/T cg02380750 chr20:61661411 NA -0.34 -5.89 -0.47 3.33e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs10489202 0.632 rs202273 chr1:167919963 A/G cg24449463 chr1:168025552 DCAF6 -0.6 -7.25 -0.55 3.86e-11 Schizophrenia; TGCT cis rs2288884 0.943 rs11084131 chr19:52514446 G/A cg13540795 chr19:52551618 ZNF432 -0.56 -4.72 -0.39 6.33e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs6683383 1.000 rs6427990 chr1:203088382 G/T cg04395153 chr1:203052423 MYOG -0.26 -4.45 -0.37 1.87e-5 Asthma; TGCT cis rs7267979 0.966 rs2261785 chr20:25262403 C/T cg03522245 chr20:25566470 NINL 0.62 6.61 0.51 1.04e-9 Liver enzyme levels (alkaline phosphatase); TGCT trans rs561341 0.783 rs512698 chr17:30292507 G/T cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs4665809 0.590 rs1122972 chr2:26418788 A/C cg26119090 chr2:26468346 HADHA;HADHB -0.92 -6.8 -0.52 3.96e-10 Gut microbiome composition (summer); TGCT cis rs9486719 1.000 rs12530462 chr6:97053514 C/T cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs9814567 0.964 rs6805388 chr3:134173534 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -1.01 -9.71 -0.66 6.38e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs28595532 0.841 rs115852209 chr4:119753465 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7089973 0.604 rs1924034 chr10:116578539 C/T cg03647239 chr10:116582469 FAM160B1 0.59 5.42 0.44 2.94e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs3617 0.625 rs2245647 chr3:52862753 A/G cg11645453 chr3:52864694 ITIH4 0.28 5.45 0.44 2.63e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs896854 0.714 rs572547 chr8:95966286 A/G cg23172400 chr8:95962367 TP53INP1 0.36 5.6 0.45 1.33e-7 Type 2 diabetes; TGCT cis rs7647973 1.000 rs11130190 chr3:49402137 T/C cg05785598 chr3:49045655 WDR6 0.39 4.66 0.39 7.89e-6 Menarche (age at onset); TGCT cis rs9393692 0.645 rs4145910 chr6:26313305 T/C cg13736514 chr6:26305472 NA -0.45 -6.67 -0.51 7.52e-10 Educational attainment; TGCT cis rs7666738 0.830 rs6532715 chr4:99016792 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs2727020 0.729 rs34647977 chr11:49195543 G/A cg15704280 chr7:45808275 SEPT13 -0.68 -7.44 -0.56 1.47e-11 Coronary artery disease; TGCT cis rs7552404 0.696 rs10518521 chr1:76461214 G/A cg22875332 chr1:76189707 ACADM 0.63 5.88 0.47 3.48e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs17270561 0.943 rs4478398 chr6:25694684 T/C cg16482183 chr6:26056742 HIST1H1C 0.7 4.62 0.38 9.56e-6 Iron status biomarkers; TGCT cis rs4711350 0.906 rs4713688 chr6:33789407 T/G cg18005901 chr6:33739558 LEMD2 -0.57 -5.75 -0.46 6.68e-8 Schizophrenia; TGCT cis rs1461503 0.868 rs10790543 chr11:122838311 A/C cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs2463822 0.513 rs72919445 chr11:62029078 A/C cg06239285 chr11:62104954 ASRGL1 -0.87 -5.56 -0.45 1.56e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs4443100 0.670 rs13056137 chr22:23407261 C/A cg14186256 chr22:23484241 RTDR1 0.57 4.46 0.37 1.79e-5 Serum parathyroid hormone levels; TGCT cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg11890956 chr21:40555474 PSMG1 -0.71 -6.38 -0.5 3.18e-9 Cognitive function; TGCT cis rs7267979 0.932 rs449703 chr20:25458559 C/T cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs968451 0.547 rs11704319 chr22:39722886 A/G cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.67 -0.39 7.74e-6 Primary biliary cholangitis; TGCT cis rs4455778 0.659 rs2364007 chr7:49016537 G/A cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs3015497 0.653 rs2356456 chr14:51093216 A/T cg04730355 chr14:51134070 SAV1 -0.62 -5.89 -0.47 3.32e-8 Mean platelet volume; TGCT cis rs7647973 0.626 rs62260720 chr3:49853796 T/A cg03060546 chr3:49711283 APEH -0.67 -5.93 -0.47 2.82e-8 Menarche (age at onset); TGCT cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT trans rs2727020 0.553 rs3862350 chr11:49595912 A/C cg03929089 chr4:120376271 NA -0.65 -7.57 -0.56 7.39e-12 Coronary artery disease; TGCT cis rs7904368 0.806 rs12242261 chr10:16872929 T/C cg14835575 chr10:16859367 RSU1 0.62 5.7 0.46 8.39e-8 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs6671200 0.850 rs259345 chr1:95729649 A/G cg26537280 chr1:95699037 RWDD3 -0.7 -5.55 -0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs7727544 0.735 rs270605 chr5:131651811 C/T cg24060327 chr5:131705240 SLC22A5 -0.58 -6.47 -0.5 2.06e-9 Blood metabolite levels; TGCT cis rs9486719 0.895 rs3734239 chr6:96996244 A/G cg06623918 chr6:96969491 KIAA0776 -0.99 -7.99 -0.58 7.78e-13 Migraine;Coronary artery disease; TGCT cis rs13118159 0.550 rs13123016 chr4:1340889 T/C cg20887711 chr4:1340912 KIAA1530 0.93 8.51 0.61 4.9e-14 Longevity; TGCT cis rs854765 0.583 rs7213225 chr17:17869111 T/C cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs9926296 0.548 rs6500439 chr16:89808275 A/C cg26513180 chr16:89883248 FANCA 1.07 14.89 0.8 2.19e-29 Vitiligo; TGCT cis rs71636778 0.509 rs35962879 chr1:27283456 T/C cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs736408 0.812 rs1076425 chr3:52825462 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.49 -0.37 1.6e-5 Bipolar disorder; TGCT trans rs7618501 0.602 rs7642934 chr3:50174848 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.93 -10.82 -0.7 1.3e-19 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.760 rs10826797 chr10:30690376 A/C cg13289132 chr10:30722225 MAP3K8 -0.39 -4.87 -0.4 3.3e-6 Inflammatory bowel disease; TGCT cis rs769267 0.965 rs2023882 chr19:19405405 T/C cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs5769707 0.967 rs763127 chr22:50006078 C/T cg20744362 chr22:50050164 C22orf34 0.28 4.58 0.38 1.12e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2637266 1.000 rs2395388 chr10:78357203 C/T cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs12142240 0.698 rs55670684 chr1:46835139 C/T cg00530320 chr1:46809349 NSUN4 0.27 5.55 0.45 1.68e-7 Menopause (age at onset); TGCT cis rs7666738 0.571 rs7683769 chr4:99091742 T/C cg05340658 chr4:99064831 C4orf37 0.44 4.72 0.39 6.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9583531 0.689 rs9588247 chr13:111375571 G/T cg24331049 chr13:111365604 ING1 -0.9 -8.98 -0.63 3.69e-15 Coronary artery disease; TGCT cis rs2859741 1.000 rs543121 chr1:37497098 T/C cg09363841 chr1:37513479 NA -0.2 -4.59 -0.38 1.07e-5 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs9916302 0.904 rs12450559 chr17:37694709 G/A cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.33e-6 Glomerular filtration rate (creatinine); TGCT cis rs7940866 0.801 rs2113929 chr11:130835974 G/A cg12179176 chr11:130786555 SNX19 0.63 5.96 0.47 2.39e-8 Schizophrenia; TGCT cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg15691649 chr6:25882328 NA 0.5 6.02 0.48 1.84e-8 Blood metabolite levels; TGCT cis rs6426558 0.537 rs12039370 chr1:227326472 A/G cg10327440 chr1:227177885 CDC42BPA -0.58 -6.91 -0.53 2.21e-10 Neutrophil percentage of white cells; TGCT cis rs9532580 0.710 rs9577090 chr13:41225228 G/T cg21288729 chr13:41239152 FOXO1 1.02 10.33 0.68 1.95e-18 Mean corpuscular hemoglobin; TGCT cis rs9303401 0.527 rs12939313 chr17:56755616 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.53 5.05 0.41 1.55e-6 Cognitive test performance; TGCT cis rs929354 0.772 rs1182432 chr7:157029176 A/G cg05182265 chr7:156933206 UBE3C -0.37 -8.49 -0.61 5.4e-14 Body mass index; TGCT cis rs9549260 0.816 rs7328594 chr13:41253764 T/C cg21288729 chr13:41239152 FOXO1 1.01 10.06 0.67 8.86e-18 Red blood cell count; TGCT cis rs8177253 1.000 rs8177247 chr3:133479499 T/G cg16414030 chr3:133502952 NA -0.61 -9.47 -0.65 2.44e-16 Iron status biomarkers; TGCT cis rs1903068 0.925 rs1551641 chr4:55993915 C/T cg01777861 chr4:56023843 NA 0.56 6.43 0.5 2.54e-9 Endometriosis; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg10263370 chr3:44754102 ZNF502 -0.45 -5.45 -0.44 2.66e-7 Depressive symptoms; TGCT cis rs910316 0.967 rs175505 chr14:75529619 C/T cg11812906 chr14:75593930 NEK9 -0.73 -7.01 -0.53 1.38e-10 Height; TGCT cis rs10791323 0.536 rs4937842 chr11:133734542 C/G cg03690763 chr11:133734501 NA 0.39 7.05 0.54 1.09e-10 Childhood ear infection; TGCT cis rs9926296 0.548 rs12447465 chr16:89829895 C/T cg03388025 chr16:89894329 SPIRE2 0.47 8.06 0.59 5.52e-13 Vitiligo; TGCT cis rs10986311 0.775 rs13300918 chr9:127145290 A/C cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.67 0.39 7.64e-6 Vitiligo; TGCT cis rs7666738 0.830 rs9995370 chr4:98732145 T/G cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9810089 0.868 rs4630889 chr3:136278251 T/C cg12473912 chr3:136751656 NA 0.34 4.83 0.4 3.9e-6 Gestational age at birth (child effect); TGCT cis rs908922 0.627 rs1053588 chr1:152488063 C/T cg20991723 chr1:152506922 NA 0.46 6.41 0.5 2.69e-9 Hair morphology; TGCT cis rs7246657 0.943 rs7255785 chr19:37971683 C/T cg18154014 chr19:37997991 ZNF793 0.74 5.44 0.44 2.71e-7 Coronary artery calcification; TGCT cis rs7666738 0.753 rs10004827 chr4:99037953 A/C cg17366294 chr4:99064904 C4orf37 0.74 7.53 0.56 9.32e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9894429 1.000 rs4074916 chr17:79579248 G/A cg18240062 chr17:79603768 NPLOC4 -0.66 -6.66 -0.51 7.97e-10 Eye color traits; TGCT cis rs7647973 0.580 rs12637576 chr3:49237334 C/T cg03060546 chr3:49711283 APEH 0.51 4.9 0.4 2.95e-6 Menarche (age at onset); TGCT cis rs13256369 1.000 rs7004438 chr8:8574379 C/T cg17143192 chr8:8559678 CLDN23 0.63 5.93 0.47 2.8e-8 Obesity-related traits; TGCT cis rs12908161 1.000 rs35524990 chr15:85258203 T/C cg17173187 chr15:85201210 NMB 0.59 6.77 0.52 4.55e-10 Schizophrenia; TGCT cis rs7698623 0.850 rs716808 chr4:88800136 G/T cg02735620 chr4:88950514 PKD2 -0.44 -4.78 -0.39 4.95e-6 Cardiovascular disease risk factors; TGCT cis rs17331151 0.573 rs77223362 chr3:52865125 G/A cg12962167 chr3:53033115 SFMBT1 0.44 4.96 0.41 2.28e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9902453 0.765 rs2259857 chr17:28097780 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.18 -0.59 2.89e-13 Coffee consumption (cups per day); TGCT cis rs12549902 0.966 rs17659386 chr8:41513531 T/C cg00088007 chr8:41504566 NKX6-3 0.34 5.31 0.43 4.93e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs66725070 1 rs66725070 chr15:58267416 GACAT/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.74 -0.57 3.01e-12 Barrett's esophagus; TGCT cis rs9640161 0.750 rs55974958 chr7:150037927 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.78 0.39 4.84e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs78487399 0.808 rs6757251 chr2:43734847 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.65 0.39 8.35e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs597539 0.652 rs579136 chr11:68637476 C/G cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3796352 0.527 rs11714793 chr3:52924930 A/G cg07884673 chr3:53033167 SFMBT1 0.5 5.26 0.43 6.15e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10751667 0.621 rs4075990 chr11:976614 T/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs34779708 0.966 rs113170867 chr10:35450147 C/T cg04310649 chr10:35416472 CREM -0.53 -4.71 -0.39 6.66e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs13191362 0.935 rs35378894 chr6:163123933 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.16 9.92 0.67 1.96e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7043114 0.525 rs7020874 chr9:95112560 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.54 -0.45 1.72e-7 Height; TGCT cis rs8103278 0.740 rs72626215 chr19:46294136 G/A cg14061069 chr19:46274453 DMPK -0.39 -4.99 -0.41 2.02e-6 Coronary artery disease; TGCT trans rs1814175 0.647 rs10839394 chr11:49844747 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.62e-13 Height; TGCT cis rs6089829 0.962 rs11086151 chr20:61664644 C/T cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs1568889 0.877 rs17310076 chr11:28147590 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.8 6.46 0.5 2.2e-9 Bipolar disorder; TGCT cis rs35160687 0.901 rs35281683 chr2:86526372 T/C cg12542933 chr2:85804724 VAMP8 0.4 4.81 0.4 4.21e-6 Night sleep phenotypes; TGCT cis rs9640161 0.789 rs10282458 chr7:150045302 C/T cg10018233 chr7:150070692 REPIN1 0.31 4.55 0.38 1.25e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs910316 0.737 rs2098251 chr14:75492696 G/A cg11812906 chr14:75593930 NEK9 0.59 5.59 0.45 1.36e-7 Height; TGCT cis rs7666738 0.830 rs34628820 chr4:99004764 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10501293 0.675 rs7103629 chr11:43044427 T/A cg03447554 chr11:43094025 NA 0.45 6.52 0.51 1.64e-9 Cognitive performance; TGCT cis rs9611565 0.659 rs4822034 chr22:41931010 T/C cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs13242816 1.000 rs3779513 chr7:116178992 T/C cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.51 0.44 1.95e-7 Parkinson's disease; TGCT cis rs317689 0.513 rs317659 chr12:69686132 T/A cg11871910 chr12:69753446 YEATS4 0.63 6.11 0.48 1.18e-8 Response to diuretic therapy; TGCT cis rs739496 0.615 rs847898 chr12:112163646 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs7100689 0.556 rs946893 chr10:82023524 A/G cg01528321 chr10:82214614 TSPAN14 0.7 6.87 0.52 2.78e-10 Post bronchodilator FEV1; TGCT cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs112591243 0.685 rs2839294 chr21:47917664 T/C cg10657630 chr21:48055338 PRMT2 1.06 5.21 0.42 7.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs2842992 0.830 rs2025190 chr6:160138241 C/T cg11366901 chr6:160182831 ACAT2 1.01 6.74 0.52 5.42e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs9359856 0.510 rs78649003 chr6:90454644 A/C cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.66 -0.39 7.9e-6 Bipolar disorder; TGCT cis rs2463822 0.925 rs2513075 chr11:62102408 C/T cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs78545713 0.892 rs76182849 chr6:26257950 C/T cg12260798 chr6:26240519 HIST1H4F -0.53 -4.48 -0.37 1.71e-5 Iron status biomarkers (total iron binding capacity); TGCT cis rs1045714 0.895 rs17833498 chr7:2647007 A/G cg17215154 chr7:2644645 IQCE -0.28 -4.92 -0.4 2.75e-6 Urate levels in lean individuals; TGCT cis rs11122272 0.735 rs2491408 chr1:231519248 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs7666738 0.830 rs4345191 chr4:98945408 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2130392 0.886 rs3806796 chr4:185652147 G/A cg14471096 chr4:185570637 CCDC111;CASP3 -0.52 -4.91 -0.4 2.85e-6 Kawasaki disease; TGCT cis rs8017423 0.626 rs8003363 chr14:90826840 T/C cg04374321 chr14:90722782 PSMC1 -0.57 -5.61 -0.45 1.27e-7 Mortality in heart failure; TGCT cis rs9362426 0.639 rs5009694 chr6:88131868 A/C cg10919329 chr6:88182879 SLC35A1 -0.61 -4.61 -0.38 9.99e-6 Depressive episodes in bipolar disorder; TGCT cis rs11112613 0.713 rs11112586 chr12:105939816 C/T cg03607813 chr12:105948248 NA 0.44 5.52 0.44 1.9e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs854765 0.647 rs2056842 chr17:18009028 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.72 7.52 0.56 9.79e-12 Total body bone mineral density; TGCT cis rs17052344 0.582 rs111876736 chr17:21747067 A/G cg18423549 chr17:21743878 NA -0.66 -6.21 -0.49 7.18e-9 Cutaneous psoriasis; TGCT cis rs7192750 0.562 rs2335709 chr16:71938442 G/A cg06353428 chr16:71660113 MARVELD3 0.8 7.2 0.54 5.05e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2295359 0.892 rs10789224 chr1:67605134 C/T cg12940439 chr1:67600707 NA -0.59 -5.99 -0.47 2.15e-8 Psoriasis; TGCT cis rs13191362 1.000 rs66529337 chr6:163005662 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9902453 0.904 rs4598962 chr17:28293948 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.25 0.55 4e-11 Coffee consumption (cups per day); TGCT cis rs1008375 0.932 rs4698626 chr4:17605821 G/C cg10189774 chr4:17578691 LAP3 0.57 4.9 0.4 2.93e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs950169 1.000 rs12902672 chr15:84716986 G/A cg17173187 chr15:85201210 NMB 0.47 5.22 0.42 7.36e-7 Schizophrenia; TGCT cis rs12497850 0.863 rs4974084 chr3:48939080 G/A cg06212747 chr3:49208901 KLHDC8B 0.63 5.72 0.46 7.5e-8 Parkinson's disease; TGCT cis rs6988636 0.901 rs2602001 chr8:124195974 T/C cg23067535 chr8:124195133 FAM83A 0.33 5.07 0.41 1.41e-6 Urinary uromodulin levels; TGCT cis rs711245 1.000 rs848602 chr2:36778372 G/A cg09467607 chr2:36825704 FEZ2 0.35 4.86 0.4 3.52e-6 Height; TGCT cis rs8013055 0.846 rs10147392 chr14:105978537 T/G cg23356831 chr14:105996513 TMEM121 0.37 5.55 0.45 1.68e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs12762955 0.561 rs7076107 chr10:1043647 T/C cg20503657 chr10:835505 NA -0.41 -5.33 -0.43 4.56e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs6088590 0.965 rs6119534 chr20:33441257 C/T cg24642439 chr20:33292090 TP53INP2 0.71 6.32 0.49 4.28e-9 Coronary artery disease; TGCT cis rs9486719 1.000 rs11153023 chr6:96968525 C/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs2439831 0.717 rs28495368 chr15:43895642 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.46 0.44 2.5e-7 Lung cancer in ever smokers; TGCT cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs2933343 1.000 rs789232 chr3:128603080 T/G cg11901034 chr3:128598214 ACAD9 -0.64 -5.05 -0.41 1.56e-6 IgG glycosylation; TGCT cis rs7833790 0.777 rs1005850 chr8:82692255 G/A cg27398817 chr8:82754497 SNX16 -0.83 -5.96 -0.47 2.43e-8 Diastolic blood pressure; TGCT cis rs1008375 0.618 rs6842764 chr4:17568420 C/T cg18681998 chr4:17616180 MED28 -0.76 -6.73 -0.52 5.69e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs75059851 0.756 rs2000852 chr11:133838221 C/T cg14047540 chr11:133829660 NA -0.53 -5.34 -0.43 4.37e-7 Schizophrenia; TGCT cis rs12200560 0.505 rs59296768 chr6:97075535 C/T cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs7020830 0.830 rs12554976 chr9:37244505 G/T cg14294708 chr9:37120828 ZCCHC7 1.18 15.7 0.82 2.88e-31 Schizophrenia; TGCT cis rs1153858 1.000 rs4534782 chr15:45652933 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs2204008 0.818 rs7313608 chr12:38383428 C/A cg26384229 chr12:38710491 ALG10B -0.79 -7.02 -0.53 1.26e-10 Bladder cancer; TGCT cis rs3008870 0.755 rs2755271 chr1:67474977 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.81 8.43 0.6 7.53e-14 Lymphocyte percentage of white cells; TGCT cis rs6076065 0.548 rs1112819 chr20:23323987 A/G cg11657817 chr20:23433608 CST11 0.29 5.07 0.41 1.42e-6 Facial morphology (factor 15, philtrum width); TGCT trans rs1814175 0.817 rs4881645 chr11:49791168 G/A cg03929089 chr4:120376271 NA -0.7 -8.19 -0.59 2.72e-13 Height; TGCT cis rs7937682 0.961 rs4935790 chr11:111633014 T/C cg09085632 chr11:111637200 PPP2R1B 1.16 11.37 0.71 5.71e-21 Primary sclerosing cholangitis; TGCT cis rs11874712 1.000 rs28504655 chr18:43665348 G/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs4689388 0.679 rs1046316 chr4:6304087 A/G cg25554036 chr4:6271136 WFS1 0.55 6.83 0.52 3.44e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4713118 0.955 rs9380010 chr6:27683572 A/G cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 7.0 0.53 1.44e-10 Platelet count; TGCT cis rs7524258 0.868 rs4908607 chr1:7269323 A/G cg07173049 chr1:7289937 CAMTA1 0.3 4.99 0.41 1.97e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg24675658 chr1:53192096 ZYG11B -0.84 -10.28 -0.68 2.58e-18 Monocyte count; TGCT cis rs12477438 0.765 rs13406288 chr2:99589585 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs1847202 0.826 rs11925587 chr3:72952227 A/G cg25664220 chr3:72788482 NA 0.35 4.51 0.38 1.49e-5 Motion sickness; TGCT cis rs2404602 0.735 rs283789 chr15:76777577 G/A cg22467129 chr15:76604101 ETFA -0.48 -4.98 -0.41 2.04e-6 Blood metabolite levels; TGCT cis rs2562456 0.834 rs2173727 chr19:21673957 C/T cg01304269 chr19:21688519 ZNF429 -0.58 -4.8 -0.4 4.49e-6 Pain; TGCT cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg03388025 chr16:89894329 SPIRE2 0.38 5.72 0.46 7.5e-8 Vitiligo; TGCT cis rs9653442 0.545 rs2009094 chr2:100765077 G/A cg22139774 chr2:100720529 AFF3 -0.36 -5.65 -0.45 1.04e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9921338 0.961 rs72773830 chr16:11412823 G/C cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs3820068 0.822 rs11581917 chr1:15805722 G/A cg05660106 chr1:15850417 CASP9 1.13 11.01 0.7 4.37e-20 Systolic blood pressure; TGCT cis rs151349 0.555 rs151343 chr20:57583298 C/G cg23907860 chr20:57583709 CTSZ 0.19 5.97 0.47 2.34e-8 Platelet distribution width; TGCT cis rs1801251 0.963 rs7562712 chr2:233606580 A/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs72781680 0.898 rs55846516 chr2:24158003 T/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs13118159 0.872 rs1882105 chr4:1345956 T/C cg20887711 chr4:1340912 KIAA1530 0.57 5.16 0.42 9.57e-7 Longevity; TGCT cis rs77972916 0.561 rs72788900 chr2:43559087 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.46 -0.37 1.78e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs6964587 1.000 rs35317449 chr7:91637010 G/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs12142240 0.698 rs72885198 chr1:46812888 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.73 0.46 7.19e-8 Menopause (age at onset); TGCT cis rs10504229 0.953 rs57131327 chr8:58171895 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs904251 0.864 rs2797801 chr6:37487161 A/G cg08126542 chr6:37504118 NA -0.44 -5.94 -0.47 2.73e-8 Cognitive performance; TGCT cis rs9858542 0.537 rs35869135 chr3:49359102 A/G cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.54 0.38 1.29e-5 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs2982552 0.844 rs2982554 chr6:152058010 G/T cg22157087 chr6:152012887 ESR1 -0.2 -4.9 -0.4 2.94e-6 Bone properties (heel); TGCT cis rs7582180 0.676 rs11680660 chr2:100931738 G/C cg14675211 chr2:100938903 LONRF2 0.53 5.24 0.43 6.82e-7 Intelligence (multi-trait analysis); TGCT cis rs17826219 0.706 rs609472 chr17:28951427 T/C cg19761014 chr17:28927070 LRRC37B2 0.57 4.89 0.4 3.05e-6 Body mass index; TGCT cis rs3820928 0.904 rs2217359 chr2:227759892 C/T cg11843606 chr2:227700838 RHBDD1 -0.55 -4.94 -0.41 2.42e-6 Pulmonary function; TGCT cis rs2439831 1.000 rs2584726 chr15:43715382 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs7027203 0.828 rs4743934 chr9:96581893 A/G cg14396892 chr9:96623032 NA -0.29 -6.22 -0.49 7.08e-9 DNA methylation (variation); TGCT cis rs208520 0.690 rs10944872 chr6:66708239 T/G cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs617219 0.710 rs16876598 chr5:78573970 T/C cg09550809 chr5:78407562 BHMT -0.37 -5.24 -0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1878931 0.582 rs27231 chr16:3434966 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.77 6.6 0.51 1.06e-9 Body mass index (adult); TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.57 5.13 0.42 1.08e-6 Prudent dietary pattern; TGCT cis rs2197308 0.765 rs7295711 chr12:37903631 C/T cg26384229 chr12:38710491 ALG10B 0.89 7.98 0.58 8.43e-13 Morning vs. evening chronotype; TGCT cis rs4924544 1 rs4924544 chr15:41693455 G/T cg18705301 chr15:41695430 NDUFAF1 -0.49 -6.8 -0.52 3.93e-10 Eosinophil percentage of white cells; TGCT cis rs2180341 0.618 rs11961994 chr6:127649350 A/G cg24812749 chr6:127587940 RNF146 -0.59 -5.06 -0.41 1.48e-6 Breast cancer; TGCT cis rs8072100 0.967 rs9894905 chr17:45485982 C/T cg08085267 chr17:45401833 C17orf57 -0.51 -5.6 -0.45 1.34e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6964587 1.000 rs7811564 chr7:91663364 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs1981331 1.000 rs75843712 chr21:47976115 A/G cg23283320 chr21:48055893 PRMT2 1.29 5.89 0.47 3.42e-8 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs910316 0.967 rs4903293 chr14:75656568 A/G cg23033748 chr14:75592666 NEK9 -0.27 -4.51 -0.38 1.5e-5 Height; TGCT cis rs5750830 0.649 rs5750813 chr22:39795228 G/C cg02038168 chr22:39784481 NA -0.77 -6.42 -0.5 2.68e-9 Intelligence (multi-trait analysis); TGCT cis rs6088590 0.965 rs6120727 chr20:33374102 T/C cg24642439 chr20:33292090 TP53INP2 0.69 6.13 0.48 1.09e-8 Coronary artery disease; TGCT cis rs6089829 0.692 rs6122349 chr20:61664096 T/C cg03213289 chr20:61660250 NA 0.57 6.76 0.52 4.74e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs13326165 0.585 rs35860312 chr3:52387078 T/C cg27565382 chr3:53032988 SFMBT1 0.38 5.06 0.41 1.5e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs919433 0.680 rs2124317 chr2:198477606 G/A cg00792783 chr2:198669748 PLCL1 0.5 4.67 0.39 7.61e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs4689388 0.926 rs4688986 chr4:6285797 C/A cg14416269 chr4:6271139 WFS1 0.39 5.25 0.43 6.47e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4304924 0.500 rs12585725 chr13:79220899 C/A cg01819759 chr13:79234251 RNF219 0.86 7.64 0.57 5.22e-12 Large artery stroke; TGCT cis rs1801251 0.896 rs2197563 chr2:233687080 G/A cg25237894 chr2:233734115 C2orf82 -0.27 -4.96 -0.41 2.31e-6 Coronary artery disease; TGCT cis rs3015497 0.967 rs8018308 chr14:51122633 T/C cg04730355 chr14:51134070 SAV1 -0.51 -4.63 -0.38 8.95e-6 Mean platelet volume; TGCT cis rs7937682 0.562 rs10891276 chr11:111370415 A/C cg09085632 chr11:111637200 PPP2R1B -0.63 -5.85 -0.47 4.01e-8 Primary sclerosing cholangitis; TGCT cis rs79976124 0.879 rs12214239 chr6:66636059 A/G cg07460842 chr6:66804631 NA 0.56 5.03 0.41 1.71e-6 Type 2 diabetes; TGCT cis rs7666738 0.830 rs17026973 chr4:98680041 T/A cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.41e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs79349575 0.783 rs4793998 chr17:47019899 C/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs1008375 0.966 rs6813375 chr4:17649499 T/G cg16339924 chr4:17578868 LAP3 0.67 5.55 0.45 1.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10501293 1.000 rs2862694 chr11:43064753 C/T cg03447554 chr11:43094025 NA 0.46 6.64 0.51 8.85e-10 Cognitive performance; TGCT cis rs2404602 0.583 rs12438741 chr15:76542114 C/A cg22467129 chr15:76604101 ETFA -0.62 -8.06 -0.59 5.34e-13 Blood metabolite levels; TGCT cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg06481639 chr22:41940642 POLR3H 0.73 6.49 0.5 1.83e-9 Vitiligo; TGCT cis rs6695640 0.857 rs1555663 chr1:17725011 T/C cg25979543 chr1:17888104 ARHGEF10L -0.24 -4.6 -0.38 1.03e-5 Mean platelet volume; TGCT cis rs7246657 0.943 rs4802766 chr19:37981933 T/C cg18154014 chr19:37997991 ZNF793 0.87 5.63 0.45 1.17e-7 Coronary artery calcification; TGCT cis rs12950390 0.853 rs11079792 chr17:45863311 T/C cg06532163 chr17:45867833 NA 0.37 5.96 0.47 2.45e-8 IgG glycosylation; TGCT cis rs9372498 0.572 rs10484289 chr6:118827836 T/C cg21191810 chr6:118973309 C6orf204 -0.39 -5.04 -0.41 1.62e-6 Diastolic blood pressure; TGCT cis rs10769945 0.500 rs217203 chr11:1972456 G/C cg06503573 chr11:1949039 TNNT3 -0.26 -4.59 -0.38 1.08e-5 DNA methylation (variation); TGCT cis rs478304 0.934 rs12801731 chr11:65549606 T/C cg17480646 chr11:65405466 SIPA1 0.41 5.03 0.41 1.7e-6 Acne (severe); TGCT cis rs9581857 0.547 rs9581868 chr13:28070682 C/T cg22138327 chr13:27999177 GTF3A 0.73 4.45 0.37 1.87e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs6901250 0.851 rs339313 chr6:117179501 C/T cg12892004 chr6:117198278 RFX6 -0.55 -6.76 -0.52 4.74e-10 C-reactive protein levels; TGCT cis rs9796 0.745 rs2947493 chr15:41375694 G/A cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.76 -0.52 4.79e-10 Menopause (age at onset); TGCT trans rs17818859 0.661 rs7594893 chr2:134645345 C/G cg15779785 chr12:2521414 CACNA1C -0.59 -6.68 -0.51 7.24e-10 Neurofibrillary tangles; TGCT cis rs9611519 1.000 rs9611519 chr22:41613188 C/T cg03806693 chr22:41940476 POLR3H -0.68 -6.38 -0.5 3.17e-9 Neuroticism; TGCT cis rs9914988 0.943 rs2242345 chr17:27185827 C/T cg20469991 chr17:27169893 C17orf63 0.71 5.15 0.42 9.95e-7 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs12541335 0.639 rs3923433 chr8:22169798 A/T cg09517075 chr8:22133004 PIWIL2 0.25 4.99 0.41 2.02e-6 Hypertriglyceridemia; TGCT cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg10802521 chr3:52805072 NEK4 -0.76 -10.05 -0.67 9.74e-18 Bipolar disorder; TGCT cis rs8103278 1.000 rs8108864 chr19:46301671 G/A cg11657440 chr19:46296263 DMWD -0.6 -5.78 -0.46 5.75e-8 Coronary artery disease; TGCT cis rs9913156 0.793 rs55974786 chr17:4567564 T/C cg00122941 chr17:4613640 ARRB2 0.88 7.51 0.56 1.03e-11 Lymphocyte counts; TGCT cis rs9486719 1.000 rs13210597 chr6:96969694 C/A cg18709589 chr6:96969512 KIAA0776 -0.72 -5.28 -0.43 5.64e-7 Migraine;Coronary artery disease; TGCT cis rs1218582 0.772 rs2335408 chr1:154915977 G/A cg03351412 chr1:154909251 PMVK 0.51 4.82 0.4 4.18e-6 Prostate cancer; TGCT cis rs9436747 0.641 rs12042884 chr1:66053192 C/G cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.04 0.41 1.59e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs1215050 0.791 rs783950 chr4:98878395 C/T cg05340658 chr4:99064831 C4orf37 -0.47 -5.94 -0.47 2.62e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs72781680 0.665 rs72788298 chr2:24104293 T/C cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg03264133 chr6:25882463 NA 0.86 8.95 0.63 4.38e-15 Blood metabolite levels; TGCT cis rs9467711 0.790 rs35942569 chr6:26339131 A/G cg05948654 chr6:25930507 SLC17A2 0.36 4.59 0.38 1.06e-5 Autism spectrum disorder or schizophrenia; TGCT trans rs77457752 0.525 rs7874947 chr9:13899539 A/C cg23609682 chr1:3070786 PRDM16 0.51 6.81 0.52 3.8e-10 Breast cancer; TGCT cis rs72781680 0.665 rs2953028 chr2:24068126 T/C cg08917208 chr2:24149416 ATAD2B 0.78 4.85 0.4 3.62e-6 Lymphocyte counts; TGCT cis rs11718455 0.960 rs1852037 chr3:44003720 G/T cg08738300 chr3:44038990 NA -0.84 -6.35 -0.5 3.75e-9 Coronary artery disease; TGCT cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg17554472 chr22:41940697 POLR3H -0.5 -5.37 -0.43 3.72e-7 Vitiligo; TGCT cis rs5769765 0.825 rs9616780 chr22:50292763 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.86 -0.73 3.71e-22 Schizophrenia; TGCT cis rs4273100 0.688 rs1467028 chr17:19174874 T/C cg01534423 chr17:18965556 NA 0.79 7.12 0.54 7.86e-11 Schizophrenia; TGCT cis rs9653442 0.675 rs961788 chr2:100641459 T/C cg07810366 chr2:100720526 AFF3 -0.4 -6.53 -0.51 1.5e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs478304 0.651 rs11604462 chr11:65551648 G/A cg17480646 chr11:65405466 SIPA1 -0.55 -6.45 -0.5 2.28e-9 Acne (severe); TGCT cis rs12477438 0.520 rs10865029 chr2:99718298 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs7666738 0.830 rs13121766 chr4:98935766 A/C cg18180107 chr4:99064573 C4orf37 0.55 4.98 0.41 2.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4268898 0.722 rs2288072 chr2:24390517 G/A cg02683114 chr2:24398427 C2orf84 0.2 4.79 0.4 4.63e-6 Asthma; TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg22166914 chr1:53195759 ZYG11B 0.38 6.52 0.51 1.6e-9 Monocyte count; TGCT cis rs4746818 1.000 rs10733850 chr10:70959617 C/T cg11621586 chr10:70884670 VPS26A 1.1 7.75 0.57 2.8e-12 Left atrial antero-posterior diameter; TGCT cis rs4237845 0.742 rs3751330 chr12:58290226 T/C cg02175503 chr12:58329896 NA 0.53 5.63 0.45 1.16e-7 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.744 rs66474616 chr12:38461564 G/A cg13010199 chr12:38710504 ALG10B 0.64 5.09 0.42 1.27e-6 Bladder cancer; TGCT cis rs1570884 0.516 rs9535268 chr13:50175478 C/A cg03651054 chr13:50194643 NA 0.33 5.28 0.43 5.66e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs3733585 0.673 rs9994266 chr4:9954450 C/T cg00071950 chr4:10020882 SLC2A9 -0.52 -6.27 -0.49 5.44e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs5769707 0.904 rs7288869 chr22:50015327 C/T cg20744362 chr22:50050164 C22orf34 0.27 4.44 0.37 1.95e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs61884328 0.733 rs74898661 chr11:47225730 G/A cg13308137 chr11:47528955 CUGBP1 0.38 4.47 0.37 1.76e-5 Total body bone mineral density (age over 60); TGCT cis rs8064299 0.597 rs6501736 chr17:72775358 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.91 10.11 0.67 6.79e-18 Monocyte count; TGCT cis rs3784262 1.000 rs12910113 chr15:58248373 A/C cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.69 -0.57 3.95e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs735396 1.000 rs735396 chr12:121438844 T/C cg02403541 chr12:121454288 C12orf43 0.66 6.27 0.49 5.35e-9 N-glycan levels; TGCT cis rs9467773 0.620 rs9461275 chr6:26590801 C/T cg05738196 chr6:26577821 NA 0.88 11.13 0.71 2.26e-20 Intelligence (multi-trait analysis); TGCT cis rs17376456 1.000 rs13163610 chr5:93548877 A/C cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT trans rs4650994 0.524 rs2811299 chr1:178586377 A/G cg05059571 chr16:84539110 KIAA1609 0.53 10.64 0.69 3.54e-19 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2338224 1.000 rs12697709 chr5:71747083 A/G cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs1218582 0.772 rs6699043 chr1:154913021 T/C cg06221963 chr1:154839813 KCNN3 -0.71 -11.67 -0.72 1.1e-21 Prostate cancer; TGCT cis rs854765 0.724 rs62072049 chr17:17906520 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.77 7.86 0.58 1.55e-12 Total body bone mineral density; TGCT cis rs17376456 0.569 rs2045019 chr5:93201971 C/T cg25358565 chr5:93447407 FAM172A -0.81 -6.54 -0.51 1.47e-9 Diabetic retinopathy; TGCT cis rs7666738 0.753 rs11932536 chr4:98930105 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs941408 0.963 rs1640268 chr19:2791469 T/C cg06609049 chr19:2785107 THOP1 0.82 8.22 0.59 2.31e-13 Total cholesterol levels; TGCT cis rs4081724 0.565 rs7253994 chr19:33805678 T/A cg18823272 chr19:34111733 CHST8 0.42 4.69 0.39 7.05e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10256972 0.528 rs7784607 chr7:1178694 A/G cg18765753 chr7:1198926 ZFAND2A -0.55 -6.48 -0.5 1.94e-9 Longevity;Endometriosis; TGCT cis rs28595532 0.920 rs116834347 chr4:119774155 C/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs478304 0.651 rs12225620 chr11:65505448 T/C cg27068330 chr11:65405492 SIPA1 -0.95 -9.64 -0.65 9.63e-17 Acne (severe); TGCT cis rs9942416 0.660 rs17563686 chr5:74984818 A/T cg19683494 chr5:74908142 NA 0.59 6.29 0.49 4.99e-9 Age-related disease endophenotypes; TGCT cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg10862848 chr6:42927986 GNMT -0.38 -4.53 -0.38 1.34e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9303401 0.573 rs35104446 chr17:57180234 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs11030122 0.673 rs10835601 chr11:4106416 G/A cg18678763 chr11:4115507 RRM1 -0.47 -5.63 -0.45 1.17e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs2832191 0.716 rs9983051 chr21:30371890 C/T cg08807101 chr21:30365312 RNF160 0.64 6.03 0.48 1.72e-8 Dental caries; TGCT trans rs2688608 0.901 rs2664280 chr10:75617344 A/T cg13918328 chr10:52500089 ASAH2B -0.65 -6.62 -0.51 9.63e-10 Inflammatory bowel disease; TGCT cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs3733585 0.673 rs4560411 chr4:9953361 A/G cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs611744 0.967 rs2600614 chr8:109198079 T/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs28735056 0.904 rs9967107 chr18:77633343 C/T cg20368463 chr18:77673604 PQLC1 0.39 4.79 0.39 4.74e-6 Schizophrenia; TGCT cis rs6570726 0.689 rs411785 chr6:145888398 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs853679 0.517 rs6922063 chr6:28094366 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs6750047 0.868 rs1431332 chr2:38280253 G/A cg07380506 chr2:38303506 CYP1B1 0.59 5.17 0.42 9.08e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs2299587 0.560 rs3913556 chr8:17781401 A/G cg01800426 chr8:17659068 MTUS1 -0.65 -5.63 -0.45 1.14e-7 Economic and political preferences; TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg13189271 chr6:15365693 JARID2 1.01 5.11 0.42 1.19e-6 Gambling; TGCT cis rs782590 0.902 rs782600 chr2:55848040 T/C cg03859395 chr2:55845619 SMEK2 0.9 11.04 0.7 3.81e-20 Metabolic syndrome; TGCT cis rs9467773 1.000 rs2208331 chr6:26507319 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs9341808 0.754 rs978814 chr6:80959912 G/T cg08355045 chr6:80787529 NA 0.28 4.84 0.4 3.84e-6 Sitting height ratio; TGCT cis rs8062405 1.000 rs62037371 chr16:28890131 C/A cg09754948 chr16:28834200 ATXN2L 0.6 4.46 0.37 1.79e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1008375 0.932 rs964012 chr4:17619184 A/G cg16339924 chr4:17578868 LAP3 0.71 5.7 0.46 8.2e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17036101 1.000 rs35877199 chr3:12299660 G/A cg00909094 chr3:12586368 NA 0.5 4.51 0.38 1.5e-5 Type 2 diabetes; TGCT cis rs67311347 1.000 rs13095055 chr3:40505666 G/T cg17264618 chr3:40429014 ENTPD3 -0.33 -4.85 -0.4 3.66e-6 Renal cell carcinoma; TGCT cis rs832540 0.552 rs702681 chr5:56218029 C/T cg24531977 chr5:56204891 C5orf35 -0.59 -5.53 -0.44 1.81e-7 Coronary artery disease; TGCT cis rs2933343 0.553 rs35979399 chr3:128697313 G/A cg11901034 chr3:128598214 ACAD9 -0.57 -5.29 -0.43 5.34e-7 IgG glycosylation; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg20007245 chr22:24372913 LOC391322 -0.74 -7.49 -0.56 1.11e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1062177 1.000 rs12654573 chr5:151207473 T/G cg00977110 chr5:151150581 G3BP1 0.39 4.46 0.37 1.84e-5 Preschool internalizing problems; TGCT cis rs2120019 0.608 rs8042558 chr15:75320433 G/T cg09165964 chr15:75287851 SCAMP5 -1.17 -10.87 -0.7 9.5e-20 Blood trace element (Zn levels); TGCT cis rs7246657 0.639 rs3112434 chr19:38198148 G/T cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs5769765 1.000 rs34774661 chr22:50267508 C/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs4319547 0.695 rs4758662 chr12:122924778 G/A cg08088222 chr12:122070432 ORAI1 0.26 4.46 0.37 1.84e-5 Body mass index; TGCT cis rs35306767 0.623 rs36051896 chr10:1155747 T/C cg26597838 chr10:835615 NA 0.52 5.51 0.44 1.96e-7 Eosinophil percentage of granulocytes; TGCT cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.17 0.48 8.71e-9 Schizophrenia; TGCT cis rs425277 0.585 rs2222217 chr1:2063164 G/A cg03732007 chr1:2071316 PRKCZ -0.28 -6.22 -0.49 6.91e-9 Height; TGCT cis rs367943 1.000 rs348963 chr5:112819027 A/G cg12552261 chr5:112820674 MCC -0.25 -5.06 -0.41 1.5e-6 Type 2 diabetes; TGCT cis rs2307449 0.704 rs758131 chr15:89884301 T/A cg24365117 chr15:89879190 POLG 0.31 4.61 0.38 9.71e-6 Menopause (age at onset); TGCT cis rs11190604 0.767 rs11190531 chr10:102187310 T/A cg16342193 chr10:102329863 NA -0.4 -5.02 -0.41 1.74e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2153535 0.607 rs9502722 chr6:8541483 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.61 0.45 1.23e-7 Motion sickness; TGCT cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg15105969 chr2:36825350 FEZ2 0.64 6.44 0.5 2.41e-9 Height; TGCT cis rs2153535 0.580 rs1932280 chr6:8473654 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg10047753 chr17:41438598 NA 0.98 10.04 0.67 1.01e-17 Menopause (age at onset); TGCT trans rs6089829 0.851 rs6122346 chr20:61661822 C/G cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.56 5.09 0.42 1.3e-6 Prudent dietary pattern; TGCT cis rs56104184 0.725 rs4347731 chr19:49385154 A/G cg21252483 chr19:49399788 TULP2 -0.42 -5.7 -0.46 8.1e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs13242816 1.000 rs17138767 chr7:116137677 A/G cg16553024 chr7:116138462 CAV2 -0.44 -5.31 -0.43 4.81e-7 P wave duration; TGCT trans rs208520 0.955 rs9453664 chr6:66976079 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.82 7.48 0.56 1.21e-11 Exhaled nitric oxide output; TGCT cis rs981844 0.885 rs62325082 chr4:154661274 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2730245 0.527 rs2788470 chr7:158649801 G/T cg11984989 chr7:158649758 WDR60 0.98 7.5 0.56 1.05e-11 Height; TGCT trans rs1496653 0.602 rs34916962 chr3:23528743 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs9467711 0.606 rs68072215 chr6:26377927 T/C cg10795676 chr6:26370623 BTN3A2 -0.47 -4.77 -0.39 5.18e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2456568 0.802 rs8181567 chr11:93637209 C/T cg14065697 chr11:93583672 C11orf90 -0.38 -4.74 -0.39 5.65e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1538970 1.000 rs17395553 chr1:45864761 C/T cg05343316 chr1:45956843 TESK2 0.72 5.53 0.44 1.82e-7 Platelet count; TGCT trans rs2727020 0.636 rs11040368 chr11:49453602 C/A cg15704280 chr7:45808275 SEPT13 -0.77 -8.75 -0.62 1.29e-14 Coronary artery disease; TGCT cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.28 -0.43 5.51e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg24675658 chr1:53192096 ZYG11B 0.77 8.95 0.63 4.31e-15 Monocyte count; TGCT cis rs7017914 0.967 rs35207116 chr8:71708971 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs6121246 0.697 rs6088856 chr20:30226543 C/G cg21427119 chr20:30132790 HM13 -0.36 -4.96 -0.41 2.26e-6 Mean corpuscular hemoglobin; TGCT cis rs1062177 1.000 rs72802204 chr5:151183183 T/C cg00977110 chr5:151150581 G3BP1 0.4 4.56 0.38 1.23e-5 Preschool internalizing problems; TGCT cis rs8177253 0.761 rs1830083 chr3:133508551 G/A cg11941060 chr3:133502564 NA -0.31 -6.66 -0.51 7.82e-10 Iron status biomarkers; TGCT cis rs2197308 0.765 rs12824529 chr12:37931656 T/C cg13010199 chr12:38710504 ALG10B 0.66 5.33 0.43 4.41e-7 Morning vs. evening chronotype; TGCT cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs9467773 1.000 rs9467797 chr6:26568473 A/T cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs2067615 0.579 rs10507214 chr12:107194461 G/A cg15890332 chr12:107067104 RFX4 0.28 5.61 0.45 1.27e-7 Heart rate; TGCT cis rs3820068 0.608 rs2057304 chr1:16017710 A/G cg17385448 chr1:15911702 AGMAT 0.34 4.67 0.39 7.66e-6 Systolic blood pressure; TGCT cis rs6901250 0.523 rs641338 chr6:117086265 C/A cg12892004 chr6:117198278 RFX6 0.39 5.01 0.41 1.87e-6 C-reactive protein levels; TGCT cis rs12887734 0.524 rs722637 chr14:104261723 G/T cg26031613 chr14:104095156 KLC1 0.74 6.48 0.5 1.97e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.505 rs269286 chr1:53169018 C/T cg22166914 chr1:53195759 ZYG11B -0.43 -7.51 -0.56 1.01e-11 Monocyte count; TGCT cis rs7586879 0.662 rs2384059 chr2:25100338 C/T cg01884057 chr2:25150051 NA 0.33 6.31 0.49 4.6e-9 Body mass index; TGCT cis rs6840360 0.642 rs2709818 chr4:152382634 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs13102973 0.720 rs13122251 chr4:135887466 C/T cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs13256369 1.000 rs13271966 chr8:8575472 T/C cg17143192 chr8:8559678 CLDN23 0.63 5.93 0.47 2.8e-8 Obesity-related traits; TGCT cis rs12780845 0.540 rs10904904 chr10:17240640 G/C cg01003015 chr10:17271136 VIM -0.62 -5.69 -0.46 8.55e-8 Homocysteine levels; TGCT trans rs4650994 0.525 rs4650997 chr1:178530744 T/A cg05059571 chr16:84539110 KIAA1609 -0.54 -11.05 -0.7 3.58e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs78456975 1.000 rs111935361 chr2:1554192 C/A cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs6121246 0.609 rs6089075 chr20:30392884 A/G cg10886678 chr20:30946050 ASXL1 -0.57 -4.79 -0.4 4.68e-6 Mean corpuscular hemoglobin; TGCT cis rs422249 0.512 rs174561 chr11:61582708 T/C cg01500311 chr11:61656094 FADS3 -0.29 -4.98 -0.41 2.1e-6 Trans fatty acid levels; TGCT cis rs77861329 0.920 rs808787 chr3:52203249 G/A cg08692210 chr3:52188851 WDR51A 0.93 4.79 0.4 4.61e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg20607798 chr8:58055168 NA 0.65 5.43 0.44 2.86e-7 Developmental language disorder (linguistic errors); TGCT cis rs6693567 0.565 rs12736375 chr1:150411912 T/C cg09579323 chr1:150459698 TARS2 0.52 4.62 0.38 9.56e-6 Migraine; TGCT cis rs611744 0.967 rs637626 chr8:109235785 G/T cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs2456568 0.695 rs55756119 chr11:93689909 A/G cg26875233 chr11:93583750 C11orf90 0.39 4.76 0.39 5.28e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1577917 0.958 rs12665542 chr6:86544443 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.19 -0.42 8.51e-7 Response to antipsychotic treatment; TGCT cis rs9911578 0.967 rs8182277 chr17:57144367 C/T cg05425664 chr17:57184151 TRIM37 -0.68 -6.9 -0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs3617 0.573 rs9850563 chr3:52912214 G/A cg11645453 chr3:52864694 ITIH4 -0.27 -5.22 -0.42 7.32e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9300255 0.620 rs1727311 chr12:123660716 T/G cg00376283 chr12:123451042 ABCB9 0.74 5.1 0.42 1.22e-6 Neutrophil percentage of white cells; TGCT cis rs1775715 0.769 rs2799030 chr10:32172935 G/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs7226408 0.842 rs2033117 chr18:34349962 A/T cg06757138 chr18:34340585 FHOD3 0.32 5.29 0.43 5.29e-7 Obesity-related traits; TGCT trans rs28735056 0.935 rs11662267 chr18:77641902 C/G cg05926928 chr17:57297772 GDPD1 -0.7 -7.45 -0.56 1.35e-11 Schizophrenia; TGCT cis rs2777491 0.789 rs316617 chr15:41795900 C/T cg18705301 chr15:41695430 NDUFAF1 0.61 8.15 0.59 3.34e-13 Ulcerative colitis; TGCT cis rs1933488 0.866 rs7756810 chr6:153416133 A/C cg24028809 chr6:153414101 RGS17 0.21 4.67 0.39 7.69e-6 Prostate cancer; TGCT cis rs2836974 0.583 rs8132993 chr21:40716410 T/C cg11890956 chr21:40555474 PSMG1 0.76 7.42 0.55 1.63e-11 Cognitive function; TGCT cis rs2455799 0.573 rs2470523 chr3:15768091 G/C cg16303742 chr3:15540471 COLQ -0.26 -4.96 -0.41 2.26e-6 Mean platelet volume; TGCT cis rs9733 0.596 rs2867304 chr1:150630995 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs8078723 1.000 rs8070454 chr17:38160754 C/T cg17467752 chr17:38218738 THRA 0.55 5.34 0.43 4.24e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs11648796 0.879 rs12448432 chr16:778820 G/A cg27144592 chr16:783916 NARFL 0.46 6.67 0.51 7.68e-10 Height; TGCT cis rs78456975 1.000 rs10208340 chr2:1563100 G/A cg01028140 chr2:1542097 TPO -0.33 -4.58 -0.38 1.12e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs13242816 1.000 rs56309428 chr7:116150137 G/T cg16553024 chr7:116138462 CAV2 -0.44 -5.36 -0.43 3.97e-7 P wave duration; TGCT cis rs7772486 0.764 rs9399569 chr6:146242942 C/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4523957 0.651 rs9906968 chr17:2077493 G/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1667284 0.935 rs1791161 chr18:29204210 C/T cg15259973 chr18:29078565 DSG2 0.49 4.66 0.39 8.04e-6 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs2239547 0.522 rs2581779 chr3:53056199 T/C cg11645453 chr3:52864694 ITIH4 -0.34 -5.34 -0.43 4.36e-7 Schizophrenia; TGCT cis rs2721195 0.743 rs2306386 chr8:145742879 T/C cg15857475 chr8:145742913 RECQL4;LRRC14 0.85 9.13 0.63 1.58e-15 Age at first birth; TGCT cis rs11112613 0.713 rs10507192 chr12:105948247 A/G cg03607813 chr12:105948248 NA 0.52 6.36 0.5 3.47e-9 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs28785552 0.536 rs10401689 chr19:53248430 T/G cg22067481 chr19:53234126 ZNF611 -0.45 -6.04 -0.48 1.65e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs1371867 0.846 rs1660329 chr8:101304048 G/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs9486719 0.843 rs2499789 chr6:96844510 T/C cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs7617773 0.780 rs4511915 chr3:48343858 G/A cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs74400468 0.529 rs11239742 chr10:43205653 G/A cg05525499 chr10:43893015 HNRNPF -0.74 -4.86 -0.4 3.43e-6 Cannabis dependence symptom count; TGCT cis rs1008375 0.966 rs4698642 chr4:17679174 A/T cg10189774 chr4:17578691 LAP3 0.52 4.89 0.4 3.1e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs2727020 0.513 rs10839307 chr11:49609843 A/C cg11707556 chr5:10655725 ANKRD33B -0.34 -6.73 -0.52 5.61e-10 Coronary artery disease; TGCT cis rs56104184 0.775 rs117016425 chr19:49400216 C/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs10789491 1.000 rs11211342 chr1:47163098 T/C cg15501359 chr1:47185051 KIAA0494 0.82 8.15 0.59 3.35e-13 Response to hepatitis C treatment; TGCT cis rs60871478 0.945 rs62432254 chr7:804175 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.48 4.88 0.4 3.21e-6 Cerebrospinal P-tau181p levels; TGCT cis rs986417 0.818 rs767603 chr14:61098683 T/C cg27398547 chr14:60952738 C14orf39 1.57 10.0 0.67 1.28e-17 Gut microbiota (bacterial taxa); TGCT cis rs10876993 0.928 rs1689592 chr12:58057773 C/T cg15848620 chr12:58087721 OS9 -0.72 -5.88 -0.47 3.56e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs2439831 0.764 rs2447193 chr15:43929733 A/C cg19166733 chr15:44192098 FRMD5 -0.24 -4.89 -0.4 3.08e-6 Lung cancer in ever smokers; TGCT cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs6589563 0.737 rs56143464 chr11:116627056 G/A cg20660624 chr11:117307972 DSCAML1 -0.37 -4.92 -0.4 2.71e-6 Eosinophil counts; TGCT cis rs9393777 0.513 rs9368448 chr6:26649355 T/C cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs11190604 1.000 rs7080356 chr10:102266735 A/C cg16342193 chr10:102329863 NA -0.39 -5.01 -0.41 1.83e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs13188771 0.651 rs3846602 chr5:100884294 C/A cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs6964587 1.000 rs2237568 chr7:91622676 G/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6831352 0.703 rs2602862 chr4:100033221 A/G cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs7089973 0.624 rs17586888 chr10:116598121 T/C cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs13411840 1.000 rs6547968 chr2:29880979 G/A cg06611768 chr2:30145152 ALK -0.43 -4.61 -0.38 9.96e-6 Glucose homeostasis traits; TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg04234412 chr22:24373322 LOC391322 -0.87 -10.27 -0.68 2.84e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs910187 0.678 rs1046661 chr20:45817149 G/A cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs929596 0.793 rs2602376 chr2:234582051 C/T cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.29 -4.58 -0.38 1.11e-5 Total bilirubin levels in HIV-1 infection; TGCT cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs1426669 chr4:98945534 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7617773 0.780 rs35778847 chr3:48346985 G/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs797680 0.856 rs12118262 chr1:93651547 C/T cg17826107 chr1:92977322 EVI5 0.23 5.01 0.41 1.85e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs709400 0.628 rs6575983 chr14:103869849 C/G cg12935359 chr14:103987150 CKB -0.3 -4.73 -0.39 6.12e-6 Body mass index; TGCT cis rs6486730 1.000 rs7953661 chr12:129275823 T/A cg09035930 chr12:129282057 SLC15A4 0.4 5.87 0.47 3.73e-8 Systemic lupus erythematosus; TGCT cis rs875971 0.793 rs460678 chr7:65527200 C/G cg11764359 chr7:65958608 NA 0.53 4.64 0.38 8.87e-6 Aortic root size; TGCT cis rs1005224 0.654 rs8005753 chr14:76136086 A/T cg25116370 chr14:76127843 TTLL5;C14orf1 -0.57 -5.06 -0.41 1.45e-6 Large artery stroke; TGCT cis rs274567 0.501 rs2631368 chr5:131705297 T/G cg24060327 chr5:131705240 SLC22A5 0.78 8.62 0.61 2.62e-14 Blood metabolite levels; TGCT cis rs2836974 0.897 rs13339986 chr21:40605982 T/C cg11890956 chr21:40555474 PSMG1 1.03 10.54 0.69 6.18e-19 Cognitive function; TGCT cis rs12210905 1.000 rs9379965 chr6:27227061 C/T cg08851530 chr6:28072375 NA 0.92 4.87 0.4 3.26e-6 Hip circumference adjusted for BMI; TGCT cis rs908922 0.676 rs11584191 chr1:152500428 A/T cg20991723 chr1:152506922 NA -0.47 -6.66 -0.51 7.77e-10 Hair morphology; TGCT cis rs6785206 0.554 rs3772158 chr3:128516142 A/C cg25356066 chr3:128598488 ACAD9 -0.78 -4.45 -0.37 1.91e-5 Lymphocyte percentage of white cells; TGCT cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg17971929 chr21:40555470 PSMG1 0.96 8.86 0.62 6.96e-15 Cognitive function; TGCT cis rs548987 0.529 rs6456703 chr6:25826119 C/T cg03517284 chr6:25882590 NA -0.55 -4.44 -0.37 1.93e-5 Homocysteine levels; TGCT cis rs3771570 1.000 rs3771564 chr2:242355701 G/A cg21155796 chr2:242212141 HDLBP 0.89 6.33 0.49 4.15e-9 Prostate cancer; TGCT cis rs11148252 0.538 rs2274202 chr13:52722798 C/A cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.85e-8 Lewy body disease; TGCT cis rs7213347 0.707 rs216181 chr17:2172753 A/T cg20777128 chr17:1945076 DPH1;OVCA2 0.51 4.51 0.38 1.48e-5 Total body bone mineral density; TGCT cis rs13424612 0.896 rs878925 chr2:240918502 A/G cg26363272 chr2:240904871 NDUFA10 0.28 4.79 0.4 4.65e-6 Odorant perception (isobutyraldehyde); TGCT cis rs11105298 0.891 rs12228177 chr12:89862030 G/T cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2658782 0.526 rs3020062 chr11:93061159 T/C cg15737290 chr11:93063684 CCDC67 1.05 11.65 0.72 1.24e-21 Pulmonary function decline; TGCT cis rs801193 1.000 rs3857688 chr7:66127806 G/A cg18876405 chr7:65276391 NA -0.34 -5.19 -0.42 8.37e-7 Aortic root size; TGCT cis rs6964587 1.000 rs10488512 chr7:91753579 C/T cg17063962 chr7:91808500 NA 0.87 9.26 0.64 7.82e-16 Breast cancer; TGCT cis rs12200560 0.505 rs211177 chr6:97074088 C/T cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs7267979 0.903 rs6132819 chr20:25218618 C/G cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs45509595 0.841 rs370155 chr6:27782031 T/G cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.24e-6 Breast cancer; TGCT cis rs7568458 0.905 rs17026396 chr2:85759127 C/T cg02493740 chr2:85810744 VAMP5 0.27 4.83 0.4 3.93e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs17108533 0.588 rs67204286 chr14:71302188 C/T cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs17376456 0.569 rs17083377 chr5:93164870 C/G cg25358565 chr5:93447407 FAM172A 0.8 6.68 0.51 7.3e-10 Diabetic retinopathy; TGCT cis rs10883723 0.810 rs10748824 chr10:104274466 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7666738 0.830 rs6532715 chr4:99016792 G/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7568458 0.870 rs1009 chr2:85808737 A/G cg02493740 chr2:85810744 VAMP5 -0.26 -4.75 -0.39 5.51e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg02725872 chr8:58115012 NA -0.35 -4.54 -0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs9913156 0.748 rs55959711 chr17:4562581 C/A cg23387401 chr17:4582204 PELP1 0.31 4.57 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs9303401 0.659 rs3809724 chr17:57061238 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.14 0.48 1.03e-8 Cognitive test performance; TGCT cis rs17384381 0.700 rs11161616 chr1:85907625 A/G cg16011679 chr1:85725395 C1orf52 -0.88 -7.16 -0.54 6.29e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs812925 0.537 rs778139 chr2:61684564 A/G cg15711740 chr2:61764176 XPO1 0.51 4.69 0.39 7.1e-6 Immature fraction of reticulocytes; TGCT cis rs9611565 0.592 rs5996039 chr22:41981957 A/G cg06481639 chr22:41940642 POLR3H -0.62 -5.26 -0.43 6.21e-7 Vitiligo; TGCT cis rs11779988 0.545 rs421290 chr8:17766416 G/C cg01800426 chr8:17659068 MTUS1 -0.72 -5.55 -0.45 1.65e-7 Breast cancer; TGCT cis rs6542838 0.780 rs981601 chr2:99463882 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -4.78 -0.39 4.79e-6 Fear of minor pain; TGCT cis rs7615952 0.866 rs1976459 chr3:125647486 A/T cg05084668 chr3:125655381 ALG1L -0.76 -6.08 -0.48 1.39e-8 Blood pressure (smoking interaction); TGCT cis rs1215050 0.740 rs783949 chr4:99001933 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -5.03 -0.41 1.69e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11673344 0.523 rs2562605 chr19:37520204 G/A cg08039142 chr19:36980659 ZNF566 0.5 4.64 0.38 8.58e-6 Obesity-related traits; TGCT cis rs4077468 0.927 rs1342063 chr1:205912859 C/T cg26354017 chr1:205819088 PM20D1 -0.41 -4.44 -0.37 1.93e-5 Cystic fibrosis-related diabetes; TGCT cis rs6952808 0.582 rs11763870 chr7:2027448 T/C cg14004847 chr7:1930337 MAD1L1 0.28 4.68 0.39 7.53e-6 Bipolar disorder and schizophrenia; TGCT cis rs9733 0.519 rs2184833 chr1:150675483 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.49 0.37 1.63e-5 Tonsillectomy; TGCT cis rs1278769 0.786 rs3742238 chr13:113540425 C/T cg11520003 chr13:113540631 ATP11A -0.31 -4.65 -0.39 8.41e-6 Interstitial lung disease; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg12419862 chr22:24373484 LOC391322 -0.79 -8.06 -0.59 5.41e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs908922 0.743 rs10888499 chr1:152532742 C/A cg20991723 chr1:152506922 NA 0.41 5.15 0.42 9.79e-7 Hair morphology; TGCT cis rs908922 0.887 rs6587688 chr1:152529622 C/T cg20991723 chr1:152506922 NA -0.41 -5.21 -0.42 7.66e-7 Hair morphology; TGCT cis rs1865760 0.827 rs9295680 chr6:25944103 T/C cg16482183 chr6:26056742 HIST1H1C 0.53 4.93 0.4 2.57e-6 Height; TGCT cis rs3806843 0.576 rs155359 chr5:140315425 G/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.44 -5.45 -0.44 2.65e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs9467773 0.933 rs2024970 chr6:26497520 T/A cg02458000 chr6:26745757 NA 0.49 4.5 0.37 1.54e-5 Intelligence (multi-trait analysis); TGCT cis rs35160687 0.842 rs11685863 chr2:86554484 G/C cg03171300 chr2:86307199 POLR1A -0.27 -4.73 -0.39 6.08e-6 Night sleep phenotypes; TGCT cis rs79149102 0.579 rs59303424 chr15:75370014 G/A cg09165964 chr15:75287851 SCAMP5 -1.0 -5.42 -0.44 3.02e-7 Lung cancer; TGCT cis rs10751667 0.666 rs4074233 chr11:977685 G/A cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs17345786 0.906 rs58835747 chr3:101243634 T/C cg12386194 chr3:101231763 SENP7 0.61 5.75 0.46 6.52e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs62064224 0.546 rs1018866 chr17:30829664 A/C cg18200150 chr17:30822561 MYO1D 0.53 7.13 0.54 7.31e-11 Schizophrenia; TGCT cis rs6430585 0.528 rs309165 chr2:136667301 T/C cg07169764 chr2:136633963 MCM6 1.2 11.66 0.72 1.12e-21 Corneal structure; TGCT cis rs992157 0.798 rs4996257 chr2:219162836 C/T cg00012203 chr2:219082015 ARPC2 0.74 7.19 0.54 5.36e-11 Colorectal cancer; TGCT cis rs1862618 0.671 rs2591970 chr5:56232595 T/C cg12311346 chr5:56204834 C5orf35 0.57 6.13 0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3796352 1.000 rs11712653 chr3:53070875 A/C cg27565382 chr3:53032988 SFMBT1 -0.48 -5.93 -0.47 2.77e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs7208859 0.614 rs73265646 chr17:29244023 C/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.72 -0.39 6.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs644799 0.603 rs1255180 chr11:95472134 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.48 4.78 0.39 4.88e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs7618501 0.574 rs6765484 chr3:50041313 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.87 -9.34 -0.64 5.1e-16 Intelligence (multi-trait analysis); TGCT cis rs6671200 0.920 rs11165339 chr1:95674064 T/C cg26537280 chr1:95699037 RWDD3 -0.68 -5.49 -0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg07061783 chr6:25882402 NA -0.53 -5.09 -0.42 1.29e-6 Intelligence (multi-trait analysis); TGCT cis rs12549902 0.800 rs7825337 chr8:41507237 C/T cg00088007 chr8:41504566 NKX6-3 0.3 4.8 0.4 4.39e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs10114408 0.959 rs10761300 chr9:96650042 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs707040 0.921 rs707035 chr2:155214352 C/T cg18104148 chr2:154337490 NA -0.19 -4.76 -0.39 5.4e-6 Sudden cardiac arrest; TGCT trans rs10203711 0.789 rs6431616 chr2:239540279 A/G cg16021909 chr1:248021091 TRIM58 -0.71 -7.6 -0.56 6.36e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs13191362 1.000 rs66594243 chr6:163169024 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.96 7.55 0.56 8e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs670523 0.596 rs72708239 chr1:155985899 A/G cg05700447 chr1:155978627 NA 0.25 5.24 0.43 6.59e-7 Inflammatory bowel disease;Crohn's disease; TGCT cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg13393036 chr8:95962371 TP53INP1 -0.63 -8.51 -0.61 4.78e-14 Type 2 diabetes; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg00024416 chr22:24240387 NA -0.25 -4.74 -0.39 5.74e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs295140 0.502 rs12990174 chr2:201240305 C/T cg04283868 chr2:201171347 SPATS2L 0.51 4.85 0.4 3.59e-6 QT interval; TGCT cis rs28595532 0.920 rs116514715 chr4:119756280 G/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9325144 0.647 rs10875953 chr12:39050536 G/C cg26384229 chr12:38710491 ALG10B -0.56 -5.11 -0.42 1.18e-6 Morning vs. evening chronotype; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg25703541 chr22:24373054 LOC391322 0.81 8.48 0.61 5.55e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9296661 0.832 rs927858 chr6:51668949 C/T cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.6e-5 Weight loss (gastric bypass surgery); TGCT cis rs5750830 0.649 rs4821894 chr22:39809820 G/C cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs875971 0.862 rs6947339 chr7:65888470 T/C cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs11250097 0.507 rs2409779 chr8:11311340 A/T cg21775007 chr8:11205619 TDH -0.53 -4.87 -0.4 3.26e-6 Neuroticism; TGCT cis rs76878669 0.561 rs6591217 chr11:66174653 G/A cg18002602 chr11:66138449 SLC29A2 -0.53 -6.41 -0.5 2.75e-9 Educational attainment (years of education); TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg26338869 chr17:61819248 STRADA -0.56 -5.11 -0.42 1.17e-6 Prudent dietary pattern; TGCT cis rs7659604 0.517 rs56311153 chr4:122729685 T/C cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.23e-7 Type 2 diabetes; TGCT cis rs2963155 0.518 rs9324918 chr5:142767160 T/C cg17617527 chr5:142782415 NR3C1 0.85 5.42 0.44 3.01e-7 Breast cancer; TGCT cis rs4665630 0.614 rs7593191 chr2:23884357 C/T cg08063864 chr2:24346004 PFN4;LOC375190 -1.0 -4.97 -0.41 2.17e-6 Hypertension; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg03395511 chr6:291903 DUSP22 -0.69 -7.14 -0.54 6.9e-11 Menopause (age at onset); TGCT cis rs7918232 0.574 rs10458708 chr10:27455605 C/T cg14240646 chr10:27532245 ACBD5 -0.46 -7.47 -0.56 1.23e-11 Breast cancer; TGCT cis rs7677751 0.806 rs890203 chr4:55097405 A/C cg17187183 chr4:55093834 PDGFRA 0.55 7.06 0.54 1.05e-10 Corneal astigmatism; TGCT cis rs4499344 0.730 rs8103269 chr19:33097503 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs6728642 0.901 rs10179966 chr2:97845100 C/T cg26665480 chr2:98280029 ACTR1B -0.99 -5.77 -0.46 5.85e-8 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs2486012 0.826 rs17533707 chr1:44361533 C/T cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs1050631 1.000 rs1785916 chr18:33696156 A/G cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.95 0.41 2.37e-6 Esophageal squamous cell cancer (length of survival); TGCT trans rs208520 0.874 rs208481 chr6:66922636 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -9.95 -0.67 1.64e-17 Exhaled nitric oxide output; TGCT cis rs9457247 1.000 rs9457247 chr6:167392174 C/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs737008 0.922 rs28567501 chr16:11378928 C/A cg00044050 chr16:11439710 C16orf75 -0.69 -6.84 -0.52 3.29e-10 Obesity-related traits; TGCT cis rs858239 0.601 rs10263110 chr7:23160551 G/A cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs4563143 0.675 rs17498203 chr19:29279734 G/T cg04546413 chr19:29218101 NA 0.86 7.0 0.53 1.45e-10 Methadone dose in opioid dependence; TGCT cis rs9733 0.565 rs7524620 chr1:150616699 C/T cg04414720 chr1:150670196 GOLPH3L -0.39 -5.05 -0.41 1.57e-6 Tonsillectomy; TGCT cis rs7000551 0.581 rs4872487 chr8:22256414 C/T cg12081754 chr8:22256438 SLC39A14 0.34 5.09 0.42 1.31e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1570884 0.516 rs9535268 chr13:50175478 C/A cg08779649 chr13:50194554 NA 0.37 5.84 0.46 4.24e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT trans rs1814175 0.607 rs11493324 chr11:50011304 T/C cg15704280 chr7:45808275 SEPT13 -0.61 -7.07 -0.54 1.01e-10 Height; TGCT cis rs61867294 0.794 rs7896463 chr10:106666355 C/T cg08000847 chr10:105880925 C10orf78 0.56 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs3784262 1.000 rs7178497 chr15:58240333 C/T cg12031962 chr15:58353849 ALDH1A2 -0.47 -7.12 -0.54 7.5e-11 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs4824093 0.610 rs73443906 chr22:50274293 A/G cg09872104 chr7:134855509 C7orf49 -0.94 -7.68 -0.57 4.2e-12 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9926296 0.542 rs12599531 chr16:89909401 C/T cg03388025 chr16:89894329 SPIRE2 -0.36 -5.18 -0.42 8.74e-7 Vitiligo; TGCT cis rs1799949 1.000 rs8176297 chr17:41203325 T/A cg23758822 chr17:41437982 NA 0.75 7.03 0.53 1.22e-10 Menopause (age at onset); TGCT cis rs7100689 0.542 rs7096715 chr10:82195949 T/C cg00277334 chr10:82204260 NA -0.43 -5.27 -0.43 5.95e-7 Post bronchodilator FEV1; TGCT cis rs9388451 0.839 rs3799711 chr6:126075313 C/T cg05901451 chr6:126070800 HEY2 0.99 14.43 0.79 2.64e-28 Brugada syndrome; TGCT cis rs7617773 1.000 rs9832957 chr3:48185266 A/G cg11946769 chr3:48343235 NME6 -0.58 -5.27 -0.43 5.75e-7 Coronary artery disease; TGCT cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg02353165 chr6:42928485 GNMT 0.95 9.51 0.65 1.95e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs244731 1.000 rs244730 chr5:176539212 A/G cg17509989 chr5:176798049 RGS14 -0.54 -6.5 -0.5 1.74e-9 Urate levels in lean individuals; TGCT cis rs4319547 1.000 rs6489156 chr12:123100397 C/T cg23029597 chr12:123009494 RSRC2 -0.29 -4.75 -0.39 5.43e-6 Body mass index; TGCT cis rs9811920 0.809 rs4928235 chr3:99706870 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.14 0.42 1.03e-6 Axial length; TGCT cis rs916888 0.687 rs199456 chr17:44797919 C/T cg17911788 chr17:44343683 NA -0.66 -7.02 -0.53 1.25e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs782590 0.967 rs2627759 chr2:55853341 T/C cg03859395 chr2:55845619 SMEK2 0.93 11.51 0.72 2.61e-21 Metabolic syndrome; TGCT cis rs17376456 0.877 rs10213956 chr5:93460839 C/T cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs9527 0.590 rs12785223 chr10:104844011 C/T cg15744005 chr10:104629667 AS3MT 0.45 5.17 0.42 8.91e-7 Arsenic metabolism; TGCT cis rs9302065 1.000 rs9302065 chr13:95971016 C/T cg24476569 chr13:95954382 ABCC4 0.43 6.41 0.5 2.71e-9 Blood metabolite levels; TGCT cis rs7428 0.545 rs1053561 chr2:85546052 A/G cg24342717 chr2:85555507 TGOLN2 -0.47 -8.24 -0.59 2.04e-13 Ear protrusion; TGCT cis rs10484885 0.775 rs55926724 chr6:90417450 A/C cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.66 -0.39 7.9e-6 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs6754311 0.550 rs3213889 chr2:136511575 A/G cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Mosquito bite size; TGCT cis rs138880 0.542 rs9616371 chr22:50306338 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.2 -7.39 -0.55 1.9e-11 Schizophrenia; TGCT cis rs9916302 0.904 rs4794807 chr17:37531718 T/A cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 1.000 rs79561699 chr8:58170601 A/G cg08280861 chr8:58055591 NA 0.37 5.03 0.41 1.66e-6 Developmental language disorder (linguistic errors); TGCT cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg11644478 chr21:40555479 PSMG1 -0.56 -5.23 -0.42 7.09e-7 Menarche (age at onset); TGCT cis rs6545883 0.929 rs2252662 chr2:61670731 T/C cg15711740 chr2:61764176 XPO1 -0.51 -4.62 -0.38 9.42e-6 Tuberculosis; TGCT cis rs11080466 1.000 rs7228069 chr18:10897713 G/A cg02393756 chr18:9912783 VAPA -0.26 -4.71 -0.39 6.56e-6 Non-small cell lung cancer; TGCT cis rs1050631 1.000 rs1539822 chr18:33695943 C/T cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.95 0.41 2.37e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs875971 0.862 rs10950033 chr7:65739673 A/G cg11764359 chr7:65958608 NA -0.57 -5.12 -0.42 1.12e-6 Aortic root size; TGCT trans rs1814175 0.817 rs10839397 chr11:49857074 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs7086627 0.515 rs4933390 chr10:82213081 A/C cg00277334 chr10:82204260 NA -0.56 -8.5 -0.61 5e-14 Post bronchodilator FEV1; TGCT cis rs752010 0.806 rs6696511 chr1:42110888 T/C cg06885757 chr1:42089581 HIVEP3 0.26 4.46 0.37 1.81e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs12541335 0.590 rs11136002 chr8:22217082 C/T cg02463440 chr8:22132932 PIWIL2 0.26 5.02 0.41 1.78e-6 Hypertriglyceridemia; TGCT cis rs12188164 1.000 rs72717411 chr5:429124 C/G cg21144161 chr5:423903 AHRR 0.26 4.93 0.4 2.59e-6 Cystic fibrosis severity; TGCT cis rs4689388 0.926 rs9998519 chr4:6292909 C/T cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs208520 0.526 rs9354366 chr6:66788559 C/T cg07460842 chr6:66804631 NA -1.08 -15.95 -0.82 8.03e-32 Exhaled nitric oxide output; TGCT cis rs8017423 0.935 rs59179255 chr14:90691773 A/C cg04374321 chr14:90722782 PSMC1 0.77 8.03 0.58 6.42e-13 Mortality in heart failure; TGCT trans rs916888 0.773 rs199534 chr17:44824213 T/G cg07870213 chr5:140052090 DND1 0.65 7.75 0.57 2.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3806843 0.933 rs10069930 chr5:140163328 T/A cg19875535 chr5:140030758 IK 0.37 6.25 0.49 5.95e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7552404 0.727 rs1146653 chr1:76280438 A/G cg22875332 chr1:76189707 ACADM 0.63 6.96 0.53 1.71e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10883723 0.810 rs10883729 chr10:104273943 A/G cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6586111 1.000 rs7093787 chr10:82371127 C/T cg03086067 chr10:82368399 SH2D4B -0.24 -4.7 -0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs7918232 0.882 rs788237 chr10:27457932 C/T cg14442939 chr10:27389572 ANKRD26 -0.82 -5.74 -0.46 6.98e-8 Breast cancer; TGCT cis rs2486012 0.737 rs556667 chr1:44287414 G/T cg12908607 chr1:44402522 ARTN -0.68 -5.22 -0.42 7.25e-7 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.561 rs34705151 chr21:40553344 G/A cg17971929 chr21:40555470 PSMG1 -0.52 -4.57 -0.38 1.18e-5 Menarche (age at onset); TGCT cis rs7710178 0.556 rs32080 chr5:156103226 A/G cg19020398 chr5:156886415 NIPAL4 -0.32 -4.6 -0.38 1.03e-5 Airway responsiveness in chronic obstructive pulmonary disease; TGCT trans rs17685 0.753 rs1639609 chr7:75683581 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 8.92 0.63 4.95e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs797680 0.897 rs2295424 chr1:93580879 T/C cg17826107 chr1:92977322 EVI5 -0.22 -4.8 -0.4 4.4e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs769267 0.895 rs1858999 chr19:19497669 C/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.61 -5.07 -0.41 1.41e-6 Tonsillectomy; TGCT cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg03303774 chr4:1407052 NA -0.33 -5.11 -0.42 1.17e-6 Obesity-related traits; TGCT cis rs9952991 0.882 rs2847274 chr18:12777603 T/C cg23544223 chr18:12777786 NA 0.64 6.12 0.48 1.15e-8 Inflammatory skin disease; TGCT cis rs10504229 0.861 rs67042991 chr8:58191749 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2204008 0.604 rs11172718 chr12:38069819 T/C cg13010199 chr12:38710504 ALG10B 0.61 4.89 0.4 3.05e-6 Bladder cancer; TGCT cis rs2072499 0.966 rs1137703 chr1:156184458 T/C cg25208724 chr1:156163844 SLC25A44 1.08 15.41 0.81 1.37e-30 Testicular germ cell tumor; TGCT cis rs77669868 0.866 rs2735195 chr11:114051192 A/G cg01914181 chr11:114070210 ZBTB16 -0.31 -5.35 -0.43 4.04e-7 Monocyte percentage of white cells; TGCT cis rs228437 0.565 rs4526208 chr6:134957385 C/T cg09872934 chr6:134495829 SGK1 -0.58 -4.94 -0.41 2.47e-6 Melanoma; TGCT cis rs11098499 0.863 rs3733525 chr4:120447048 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs3812831 0.635 rs6560937 chr13:114945991 C/G cg15513719 chr13:114904418 NA 0.36 4.46 0.37 1.84e-5 Schizophrenia; TGCT cis rs7772486 0.790 rs9403755 chr6:146231470 C/A cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs950169 0.800 rs4099846 chr15:84956894 C/G cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs875971 1.000 rs12698523 chr7:65968113 C/G cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs1395 1.000 rs1275537 chr2:27441302 C/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.55 7.47 0.56 1.23e-11 Blood metabolite levels; TGCT cis rs7618915 0.501 rs11130308 chr3:52639257 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs4319547 0.737 rs10846920 chr12:122943231 C/T cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.77 -0.39 5.09e-6 Body mass index; TGCT cis rs763014 0.898 rs916414 chr16:632073 C/T cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs9926296 0.618 rs8058179 chr16:89846987 C/T cg26513180 chr16:89883248 FANCA -0.74 -7.19 -0.54 5.39e-11 Vitiligo; TGCT trans rs7698623 0.850 rs716808 chr4:88800136 G/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.61 -0.51 1.01e-9 Cardiovascular disease risk factors; TGCT cis rs59698941 0.527 rs1910075 chr5:132180089 A/T cg21474247 chr5:131268130 NA 0.32 5.12 0.42 1.15e-6 Apolipoprotein A-IV levels; TGCT cis rs801193 1.000 rs4717310 chr7:66161007 C/T cg00343986 chr7:65444356 GUSB 0.22 5.01 0.41 1.84e-6 Aortic root size; TGCT cis rs11690935 0.959 rs6705200 chr2:172637600 A/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs9611565 0.512 rs132767 chr22:42009520 C/T cg17554472 chr22:41940697 POLR3H -0.47 -4.94 -0.41 2.52e-6 Vitiligo; TGCT cis rs1552244 0.882 rs13099507 chr3:10031603 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.36 -0.5 3.55e-9 Alzheimer's disease; TGCT cis rs3772130 0.961 rs13072618 chr3:121391833 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.55 5.02 0.41 1.77e-6 Cognitive performance; TGCT cis rs9443645 0.901 rs4565265 chr6:79741958 A/G cg09184832 chr6:79620586 NA -0.48 -5.29 -0.43 5.43e-7 Intelligence (multi-trait analysis); TGCT cis rs9660992 0.573 rs1172139 chr1:205213962 G/A cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs6988636 0.818 rs59428574 chr8:124166061 G/A cg27053337 chr8:124217698 FAM83A 0.7 5.14 0.42 1.06e-6 Urinary uromodulin levels; TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg14893161 chr1:205819251 PM20D1 0.55 7.8 0.57 2.23e-12 Menarche (age at onset); TGCT cis rs7586879 0.681 rs6723803 chr2:25120713 G/C cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs28735056 0.591 rs2277724 chr18:77694294 C/A cg20368463 chr18:77673604 PQLC1 -0.48 -5.79 -0.46 5.4e-8 Schizophrenia; TGCT cis rs4843747 0.671 rs72818576 chr16:88111019 C/G cg06915872 chr16:87998081 BANP -0.3 -4.52 -0.38 1.44e-5 Menopause (age at onset); TGCT cis rs801193 0.660 rs2659914 chr7:66156914 C/T cg18876405 chr7:65276391 NA 0.33 4.86 0.4 3.46e-6 Aortic root size; TGCT cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg06108461 chr20:60628389 TAF4 -0.59 -8.52 -0.61 4.53e-14 Body mass index; TGCT cis rs1218582 0.596 rs11264275 chr1:154825270 G/T cg06221963 chr1:154839813 KCNN3 0.56 7.82 0.57 1.95e-12 Prostate cancer; TGCT cis rs7937682 0.575 rs7124696 chr11:111747297 A/G cg09085632 chr11:111637200 PPP2R1B 0.88 8.5 0.61 5.19e-14 Primary sclerosing cholangitis; TGCT cis rs4478858 0.684 rs4949373 chr1:31741577 G/A cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs2455799 0.552 rs2470516 chr3:15759050 T/G cg16303742 chr3:15540471 COLQ -0.25 -4.78 -0.39 4.95e-6 Mean platelet volume; TGCT cis rs6430585 0.646 rs12476116 chr2:136497199 A/G cg07169764 chr2:136633963 MCM6 1.17 10.84 0.7 1.14e-19 Corneal structure; TGCT cis rs2439831 1.000 rs2467426 chr15:43989518 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.96 6.63 0.51 9.05e-10 Lung cancer in ever smokers; TGCT cis rs6089584 0.850 rs6089634 chr20:60632566 T/C cg13770153 chr20:60521292 NA -0.6 -7.72 -0.57 3.26e-12 Body mass index; TGCT cis rs13242816 0.881 rs12672038 chr7:116187106 G/A cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs28595532 0.841 rs114385163 chr4:119737058 C/T cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs612683 0.518 rs660945 chr1:100831830 A/T cg06223162 chr1:101003688 GPR88 -0.27 -4.69 -0.39 7.09e-6 Breast cancer; TGCT cis rs1971762 0.527 rs11170590 chr12:53938913 G/A cg16917193 chr12:54089295 NA 1.02 10.38 0.68 1.5e-18 Height; TGCT cis rs9902453 1.000 rs8065261 chr17:28418041 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.52 -0.51 1.63e-9 Coffee consumption (cups per day); TGCT cis rs1008375 1.000 rs6846238 chr4:17629939 A/G cg18681998 chr4:17616180 MED28 1.02 11.4 0.72 4.89e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7959452 0.640 rs10878957 chr12:69699638 G/C cg11871910 chr12:69753446 YEATS4 0.63 6.37 0.5 3.41e-9 Blood protein levels; TGCT cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg18230493 chr5:56204884 C5orf35 0.86 6.85 0.52 3.07e-10 Initial pursuit acceleration; TGCT cis rs3087591 0.960 rs6505232 chr17:29611411 T/C cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.39 -0.55 1.94e-11 Hip circumference; TGCT cis rs8017423 0.967 rs11621431 chr14:90709221 C/T cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs68170813 0.527 rs75382408 chr7:107010406 C/T cg02696742 chr7:106810147 HBP1 -0.71 -5.96 -0.47 2.38e-8 Coronary artery disease; TGCT cis rs7017914 0.905 rs3110252 chr8:71937220 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs801193 0.844 rs2244022 chr7:66202430 A/G cg00343986 chr7:65444356 GUSB 0.21 4.59 0.38 1.07e-5 Aortic root size; TGCT cis rs12681287 0.752 rs10104242 chr8:87247714 G/C cg27223183 chr8:87520930 FAM82B -0.81 -5.77 -0.46 5.91e-8 Caudate activity during reward; TGCT cis rs236907 0.812 rs35400839 chr1:171743312 G/A cg20598894 chr1:171756153 METTL13 -0.19 -4.54 -0.38 1.32e-5 Mean platelet volume; TGCT cis rs7666738 0.579 rs7672718 chr4:98645122 A/G cg05340658 chr4:99064831 C4orf37 0.47 5.14 0.42 1.02e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs79387448 0.745 rs17027430 chr2:103163237 T/C cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs2239547 0.603 rs7644973 chr3:53082937 C/T cg11645453 chr3:52864694 ITIH4 0.3 4.84 0.4 3.73e-6 Schizophrenia; TGCT cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg03264133 chr6:25882463 NA -0.64 -5.93 -0.47 2.82e-8 Intelligence (multi-trait analysis); TGCT cis rs9443645 0.803 rs1547731 chr6:79776104 A/G cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs7639513 0.767 rs13060705 chr3:12710016 C/A cg23032965 chr3:12705835 RAF1 0.77 8.55 0.61 3.81e-14 Itch intensity from mosquito bite; TGCT cis rs6688613 0.840 rs10918607 chr1:166957803 T/C cg07049167 chr1:166818506 POGK 0.26 5.18 0.42 8.56e-7 Refractive astigmatism; TGCT cis rs9640161 0.742 rs2108853 chr7:150017589 A/C cg10018233 chr7:150070692 REPIN1 0.33 4.68 0.39 7.25e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs4273100 0.790 rs2048230 chr17:19276199 G/A cg01534423 chr17:18965556 NA 0.95 6.38 0.5 3.14e-9 Schizophrenia; TGCT trans rs877282 1.000 rs11253370 chr10:773712 G/A cg22713356 chr15:30763199 NA 1.15 9.94 0.67 1.76e-17 Uric acid levels; TGCT cis rs6088590 0.610 rs6120663 chr20:33081906 A/C cg24642439 chr20:33292090 TP53INP2 -0.66 -6.16 -0.48 9.13e-9 Coronary artery disease; TGCT cis rs1887596 0.663 rs9551305 chr13:27249860 A/G cg01312412 chr13:27282625 NA 0.28 4.98 0.41 2.07e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg12310025 chr6:25882481 NA 0.51 5.26 0.43 6.17e-7 Blood metabolite levels; TGCT cis rs42648 0.935 rs42644 chr7:89974864 G/A cg25739043 chr7:89950458 NA -0.77 -7.82 -0.57 1.96e-12 Homocysteine levels; TGCT cis rs12477438 0.798 rs6740035 chr2:99576578 C/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs72627509 0.638 rs1608165 chr4:57894717 G/C cg26694713 chr4:57773883 REST 0.62 4.62 0.38 9.46e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1406084 0.578 rs3843318 chr2:154717559 G/A cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 0.767 rs10883477 chr10:102161396 A/G cg16005271 chr10:102321736 NA 0.46 4.83 0.4 3.93e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2204008 0.616 rs1607852 chr12:38398125 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.42 0.55 1.62e-11 Bladder cancer; TGCT cis rs11098499 0.644 rs10050092 chr4:120532085 T/C cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs2842992 0.789 rs2342446 chr6:160220687 A/G cg11366901 chr6:160182831 ACAT2 1.03 6.98 0.53 1.59e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs6586111 1.000 rs7073089 chr10:82371045 C/G cg03086067 chr10:82368399 SH2D4B -0.24 -4.7 -0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs7937682 0.793 rs7130440 chr11:111417779 A/G cg09085632 chr11:111637200 PPP2R1B 0.65 6.0 0.47 2.04e-8 Primary sclerosing cholangitis; TGCT trans rs853410 0.516 rs9405690 chr6:4005552 C/T cg13911294 chr9:88951310 ZCCHC6 -0.64 -6.66 -0.51 8.02e-10 Night sleep phenotypes; TGCT cis rs2204008 0.775 rs11182513 chr12:38560252 G/C cg13010199 chr12:38710504 ALG10B 0.65 5.18 0.42 8.83e-7 Bladder cancer; TGCT cis rs3771570 1.000 rs62190367 chr2:242376276 G/A cg21155796 chr2:242212141 HDLBP 0.93 6.6 0.51 1.08e-9 Prostate cancer; TGCT cis rs919433 0.679 rs6737060 chr2:198524885 G/C cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg18735214 chr6:43276756 CRIP3 -0.56 -4.88 -0.4 3.24e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10936602 0.527 rs7628572 chr3:169539649 T/A cg08193579 chr3:169529701 LRRC34 0.28 5.16 0.42 9.55e-7 Renal cell carcinoma; TGCT cis rs9653442 0.835 rs1561230 chr2:100746642 C/T cg22139774 chr2:100720529 AFF3 0.43 7.46 0.56 1.31e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs8180040 0.764 rs62246375 chr3:47014464 G/A cg27129171 chr3:47204927 SETD2 -0.71 -8.9 -0.62 5.56e-15 Colorectal cancer; TGCT cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg17971929 chr21:40555470 PSMG1 0.67 6.29 0.49 5.06e-9 Cognitive function; TGCT cis rs4319547 0.585 rs10846792 chr12:122882374 T/C cg05707623 chr12:122985044 ZCCHC8 -0.62 -4.79 -0.4 4.63e-6 Body mass index; TGCT cis rs9858542 0.953 rs35261698 chr3:49537839 C/G cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6964587 0.934 rs73226382 chr7:91692760 T/C cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs9611519 0.828 rs28814423 chr22:41452301 G/A cg13695892 chr22:41940480 POLR3H -0.54 -4.82 -0.4 4.15e-6 Neuroticism; TGCT cis rs41271473 0.526 rs10916344 chr1:228737489 C/T cg10167378 chr1:228756711 NA 0.73 4.57 0.38 1.15e-5 Chronic lymphocytic leukemia; TGCT cis rs7659604 0.628 rs6838153 chr4:122720999 A/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.39 -0.44 3.47e-7 Type 2 diabetes; TGCT cis rs6089584 0.888 rs6061979 chr20:60617141 C/G cg06108461 chr20:60628389 TAF4 -0.69 -10.77 -0.7 1.71e-19 Body mass index; TGCT cis rs7666738 0.830 rs7664340 chr4:99037820 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.13 0.42 1.1e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs74233809 1.000 rs10883835 chr10:104884208 T/C cg05855489 chr10:104503620 C10orf26 0.82 4.44 0.37 1.97e-5 Birth weight; TGCT cis rs4604732 0.631 rs12091081 chr1:247623064 C/T cg22475246 chr1:246888027 SCCPDH 0.67 4.79 0.4 4.57e-6 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); TGCT cis rs41308713 0.606 rs77984335 chr20:37073286 G/A cg09132763 chr20:37064059 LOC388796;SNORA71D 1.34 6.47 0.5 2.09e-9 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs782590 0.557 rs7592219 chr2:55887176 T/C cg03859395 chr2:55845619 SMEK2 -0.63 -5.3 -0.43 5.01e-7 Metabolic syndrome; TGCT cis rs6866344 0.697 rs58549512 chr5:178133204 C/T cg10224037 chr5:178157518 ZNF354A 0.95 8.47 0.61 6.06e-14 Neutrophil percentage of white cells; TGCT cis rs6089829 0.855 rs6090205 chr20:61665269 A/G cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 5.05 0.41 1.52e-6 Prudent dietary pattern; TGCT cis rs6484504 0.576 rs2065208 chr11:31239457 C/T cg26647111 chr11:31128758 NA -0.35 -4.75 -0.39 5.48e-6 Red blood cell count; TGCT cis rs7267979 0.932 rs928121 chr20:25534818 A/G cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1994135 0.669 rs11052746 chr12:33697473 A/C cg06521331 chr12:34319734 NA 0.3 4.59 0.38 1.07e-5 Resting heart rate; TGCT cis rs34014631 1.000 rs78142636 chr10:103601727 G/C cg22630918 chr10:102748988 C10orf2 0.43 4.83 0.4 3.98e-6 Coronary artery calcification; TGCT cis rs2639990 1.000 rs1702831 chr18:72897368 C/A cg21330207 chr18:72916311 ZADH2 0.51 4.57 0.38 1.16e-5 Vascular endothelial growth factor levels; TGCT cis rs77372450 0.551 rs11739081 chr5:157087119 C/G cg12606933 chr5:157078573 SOX30 -0.43 -4.69 -0.39 7e-6 Bipolar disorder (body mass index interaction); TGCT cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg24829409 chr8:58192753 C8orf71 -0.57 -4.72 -0.39 6.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs8077577 1.000 rs8077577 chr17:18064730 C/T cg09161412 chr17:18057145 MYO15A -0.65 -5.36 -0.43 3.89e-7 Obesity-related traits; TGCT cis rs2242194 0.816 rs11264296 chr1:154994750 T/C cg24348479 chr1:155007323 DCST1;DCST2 0.27 5.66 0.45 9.97e-8 Schizophrenia; TGCT cis rs2354432 0.607 rs12402309 chr1:146721983 T/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs5769707 0.777 rs8138399 chr22:50044824 C/T cg05373962 chr22:49881684 NA -0.31 -6.33 -0.49 4.07e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs910316 1.000 rs4899546 chr14:75594946 G/C cg08847533 chr14:75593920 NEK9 0.96 10.86 0.7 1.05e-19 Height; TGCT cis rs1372520 0.684 rs10008964 chr4:90744721 G/A cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.11e-7 Neuroticism; TGCT cis rs910316 0.726 rs12882664 chr14:75446778 C/T cg11812906 chr14:75593930 NEK9 0.59 5.56 0.45 1.61e-7 Height; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg05457628 chr5:178986728 RUFY1 0.54 6.29 0.49 4.98e-9 Lung cancer; TGCT cis rs7267979 1.000 rs2258879 chr20:25279213 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9309473 0.660 rs56131703 chr2:73847260 C/T cg07208825 chr2:73871855 ALMS1P 0.26 5.28 0.43 5.58e-7 Metabolite levels; TGCT cis rs7727544 1.000 rs7727544 chr5:131590534 C/T cg24060327 chr5:131705240 SLC22A5 -0.62 -6.48 -0.5 1.97e-9 Blood metabolite levels; TGCT cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.45 0.37 1.88e-5 Renal cell carcinoma; TGCT cis rs7267979 1.000 rs6083828 chr20:25369918 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg13683864 chr3:40499215 RPL14 -1.16 -12.47 -0.75 1.28e-23 Renal cell carcinoma; TGCT cis rs7208859 0.573 rs73277974 chr17:29189869 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7833790 0.660 rs10091077 chr8:82705464 A/G cg23324259 chr8:82754387 SNX16 -0.58 -4.46 -0.37 1.78e-5 Diastolic blood pressure; TGCT cis rs17102423 0.559 rs11627382 chr14:65480208 A/G cg11161011 chr14:65562177 MAX -0.42 -4.94 -0.41 2.46e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs10014986 chr4:99000687 A/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg06481639 chr22:41940642 POLR3H 0.59 5.38 0.44 3.56e-7 Vitiligo; TGCT trans rs7819412 0.745 rs28591576 chr8:11080675 C/T cg15556689 chr8:8085844 FLJ10661 -0.87 -8.34 -0.6 1.2e-13 Triglycerides; TGCT cis rs1005277 0.505 rs7099777 chr10:38183569 A/C cg13531842 chr10:38383804 ZNF37A 0.38 4.55 0.38 1.24e-5 Extrinsic epigenetic age acceleration; TGCT cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs524281 0.692 rs10896076 chr11:65840668 A/G cg00563793 chr11:65837595 PACS1 0.59 5.36 0.43 3.88e-7 Electroencephalogram traits; TGCT cis rs2836974 0.897 rs8128102 chr21:40606414 G/A cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.67e-16 Cognitive function; TGCT cis rs1371867 0.810 rs1692004 chr8:101247320 T/C cg06002616 chr8:101225028 SPAG1 0.53 6.05 0.48 1.55e-8 Atrioventricular conduction; TGCT cis rs7172809 0.599 rs17471697 chr15:77762493 A/G cg22256960 chr15:77711686 NA 0.53 5.15 0.42 9.86e-7 Glucose homeostasis traits; TGCT cis rs6545883 0.929 rs6707830 chr2:61749472 G/A cg15711740 chr2:61764176 XPO1 -0.52 -4.78 -0.39 4.78e-6 Tuberculosis; TGCT cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg23205692 chr1:25664452 TMEM50A -0.47 -4.96 -0.41 2.27e-6 Erythrocyte sedimentation rate; TGCT cis rs2147959 0.824 rs6669744 chr1:228684825 T/C cg22700015 chr1:228743131 NA -0.61 -4.7 -0.39 6.82e-6 Adult asthma; TGCT cis rs769267 0.965 rs2074299 chr19:19380646 T/C cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs1372520 0.684 rs2583963 chr4:90727088 C/T cg15133208 chr4:90757351 SNCA -0.52 -6.07 -0.48 1.44e-8 Neuroticism; TGCT cis rs1245541 0.720 rs1271933 chr10:73902875 T/C cg09661010 chr10:73848153 SPOCK2 -0.37 -4.53 -0.38 1.39e-5 Insulin-like growth factors; TGCT cis rs1005277 0.522 rs11011343 chr10:38002698 A/G cg25427524 chr10:38739819 LOC399744 -0.33 -6.6 -0.51 1.07e-9 Extrinsic epigenetic age acceleration; TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs9858542 0.953 rs71324979 chr3:49619651 T/C cg03060546 chr3:49711283 APEH -0.63 -5.48 -0.44 2.28e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs4273100 0.541 rs7501702 chr17:19293727 C/T cg03910582 chr17:19030146 GRAPL -0.45 -6.22 -0.49 6.97e-9 Schizophrenia; TGCT cis rs7666738 0.830 rs7673880 chr4:99057262 A/G cg17366294 chr4:99064904 C4orf37 0.69 6.91 0.53 2.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10744422 0.920 rs3896871 chr12:123333610 G/T cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs7582180 0.629 rs11123827 chr2:100951248 C/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs6484504 0.532 rs12222329 chr11:31274340 T/C cg14844989 chr11:31128820 NA -0.25 -4.89 -0.4 3e-6 Red blood cell count; TGCT cis rs4919669 0.719 rs11818043 chr10:104391627 A/G cg05855489 chr10:104503620 C10orf26 0.74 4.73 0.39 5.9e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs12479064 0.724 rs3792150 chr2:100041849 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -4.66 -0.39 8e-6 Chronic sinus infection; TGCT cis rs7178572 1.000 rs952472 chr15:77776562 A/C cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs2840044 1.000 rs7212704 chr17:33898897 C/T cg05299278 chr17:33885742 SLFN14 -0.23 -5.32 -0.43 4.65e-7 Response to radiotherapy in cancer (late toxicity); TGCT cis rs9486719 0.901 rs13206547 chr6:97006942 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.21 -0.59 2.44e-13 Migraine;Coronary artery disease; TGCT cis rs4253772 0.513 rs9615345 chr22:46713631 C/T cg26492175 chr22:47022658 GRAMD4 0.2 4.47 0.37 1.75e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs2562456 0.917 rs2650825 chr19:21699225 A/G cg25650185 chr19:21324782 ZNF431 -0.52 -4.7 -0.39 6.74e-6 Pain; TGCT cis rs4980532 1 rs4980532 chr11:63680719 C/T cg04850017 chr11:63683019 RCOR2 0.41 6.88 0.53 2.59e-10 Pulse pressure; TGCT cis rs1857353 1.000 rs12407255 chr1:75876217 G/T cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs9388451 0.874 rs7739566 chr6:126094757 A/T cg10911889 chr6:126070802 HEY2 0.54 5.64 0.45 1.09e-7 Brugada syndrome; TGCT cis rs950169 0.922 rs4338765 chr15:84916836 G/T cg17173187 chr15:85201210 NMB 0.54 5.55 0.45 1.67e-7 Schizophrenia; TGCT cis rs6591182 0.504 rs7116712 chr11:65372518 A/G cg17480646 chr11:65405466 SIPA1 -0.51 -6.48 -0.5 1.91e-9 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs2948294 0.588 rs4840913 chr8:8116906 A/C cg06636001 chr8:8085503 FLJ10661 0.77 6.9 0.53 2.31e-10 Red cell distribution width; TGCT cis rs6570726 0.599 rs455001 chr6:145854450 A/T cg13319975 chr6:146136371 FBXO30 -0.69 -6.34 -0.49 3.92e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.846 rs1474871 chr6:146406294 G/A cg23711669 chr6:146136114 FBXO30 0.86 9.3 0.64 6.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs11627546 0.615 rs61980617 chr14:70367189 A/G cg10496350 chr14:71275911 MAP3K9 -0.89 -4.5 -0.37 1.52e-5 Red blood cell traits; TGCT cis rs116095464 0.558 rs9312978 chr5:221930 C/G cg22857025 chr5:266934 NA -0.34 -6.6 -0.51 1.09e-9 Breast cancer; TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg19723775 chr5:179050963 HNRNPH1 -0.52 -5.18 -0.42 8.62e-7 Lung cancer; TGCT trans rs7618501 1.000 rs2271961 chr3:49878113 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.554 rs61308159 chr4:152728941 G/A cg22705602 chr4:152727874 NA 0.37 6.54 0.51 1.47e-9 Intelligence (multi-trait analysis); TGCT cis rs736408 0.716 rs2239550 chr3:52822509 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.12 -0.42 1.13e-6 Bipolar disorder; TGCT cis rs6545977 0.531 rs2539981 chr2:63104904 T/C cg17519650 chr2:63277830 OTX1 0.69 6.57 0.51 1.22e-9 Prostate cancer; TGCT cis rs6663390 0.831 rs11118880 chr1:208085583 T/A cg03990033 chr1:208084030 CD34 0.54 5.61 0.45 1.26e-7 Facial morphology (factor 18); TGCT cis rs10504229 0.679 rs17801003 chr8:58050930 A/G cg02725872 chr8:58115012 NA -0.4 -4.78 -0.39 4.78e-6 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg11890956 chr21:40555474 PSMG1 1.04 10.78 0.7 1.56e-19 Cognitive function; TGCT cis rs9325144 0.556 rs34565156 chr12:39028239 G/A cg26384229 chr12:38710491 ALG10B -0.61 -5.81 -0.46 4.99e-8 Morning vs. evening chronotype; TGCT cis rs6922617 0.786 rs73417293 chr6:41342880 A/G cg07798131 chr6:41471673 NA 0.96 4.74 0.39 5.73e-6 Alzheimer's disease biomarkers; TGCT cis rs6733011 0.518 rs12712033 chr2:99457973 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.5 -4.92 -0.4 2.7e-6 Bipolar disorder; TGCT cis rs7937682 0.924 rs1784782 chr11:111525764 A/C cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs4389656 0.857 rs274699 chr5:6730332 A/C cg10857441 chr5:6722123 POLS -0.22 -4.74 -0.39 5.75e-6 Coronary artery disease; TGCT cis rs9303401 0.659 rs7216648 chr17:56790858 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs916888 0.821 rs199514 chr17:44856881 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.73 -5.0 -0.41 1.89e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4654899 0.549 rs4654873 chr1:21152384 G/A cg01072550 chr1:21505969 NA -0.42 -6.15 -0.48 9.87e-9 Superior frontal gyrus grey matter volume; TGCT cis rs9611565 0.559 rs132761 chr22:42004371 C/T cg06634786 chr22:41940651 POLR3H 0.89 8.56 0.61 3.56e-14 Vitiligo; TGCT cis rs2180341 0.920 rs4472373 chr6:127705983 G/A cg24812749 chr6:127587940 RNF146 0.99 7.63 0.57 5.24e-12 Breast cancer; TGCT cis rs2637266 1.000 rs12251434 chr10:78345468 C/A cg18941641 chr10:78392320 NA 0.4 5.02 0.41 1.77e-6 Pulmonary function; TGCT trans rs7618501 0.699 rs9821675 chr3:49902544 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.9 9.84 0.66 3.04e-17 Intelligence (multi-trait analysis); TGCT cis rs736408 0.812 rs2240920 chr3:52831009 A/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.55 -5.01 -0.41 1.79e-6 Bipolar disorder; TGCT cis rs3806843 0.966 rs2337986 chr5:140160622 C/T cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs986417 0.901 rs10139995 chr14:60947177 G/T cg27398547 chr14:60952738 C14orf39 1.42 8.68 0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs7523050 0.643 rs35050241 chr1:109404876 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs9393777 0.622 rs13191326 chr6:27031029 A/G cg16898833 chr6:26189333 HIST1H4D 0.98 5.69 0.46 8.64e-8 Intelligence (multi-trait analysis); TGCT cis rs8180040 0.726 rs10461018 chr3:46995242 C/T cg27129171 chr3:47204927 SETD2 -0.74 -9.5 -0.65 2.08e-16 Colorectal cancer; TGCT cis rs9467773 0.595 rs3846845 chr6:26444915 G/A cg05738196 chr6:26577821 NA -0.52 -5.49 -0.44 2.18e-7 Intelligence (multi-trait analysis); TGCT trans rs2469997 1.000 rs2447160 chr8:120374473 G/A cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs10791097 0.694 rs7940027 chr11:130745591 A/G cg05962950 chr11:130786565 SNX19 0.92 11.53 0.72 2.38e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs17102423 0.755 rs7154852 chr14:65553822 C/A cg11161011 chr14:65562177 MAX -0.55 -7.7 -0.57 3.74e-12 Obesity-related traits; TGCT trans rs17685 0.712 rs2158867 chr7:75815141 C/A cg19862616 chr7:65841803 NCRNA00174 0.5 8.75 0.62 1.28e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs797680 0.930 rs622608 chr1:93715219 G/A cg17826107 chr1:92977322 EVI5 0.24 5.3 0.43 5.16e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2594989 0.779 rs61275424 chr3:11595585 G/C cg00170343 chr3:11313890 ATG7 -0.68 -5.33 -0.43 4.44e-7 Circulating chemerin levels; TGCT cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs877529 0.934 rs139419 chr22:39557340 T/G cg18708252 chr22:39545030 CBX7 -0.35 -4.74 -0.39 5.7e-6 Multiple myeloma; TGCT cis rs7599312 1.000 rs7599312 chr2:213413231 C/T cg20637307 chr2:213403960 ERBB4 0.6 4.91 0.4 2.82e-6 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9911578 1.000 rs2611782 chr17:56717956 T/C cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs12510870 0.566 rs10004505 chr4:74437998 G/A cg05868023 chr4:75230803 EREG 0.55 4.97 0.41 2.18e-6 Iris color (b* coordinate); TGCT cis rs2463822 0.764 rs7125402 chr11:62097259 C/T cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs886126 1.000 rs7973104 chr12:111670774 C/G cg10833066 chr12:111807467 FAM109A 0.32 5.18 0.42 8.75e-7 Coronary heart disease; TGCT cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg08392591 chr16:89556376 ANKRD11 0.6 5.68 0.45 9.12e-8 Multiple myeloma (IgH translocation); TGCT cis rs11190604 0.767 rs7085426 chr10:102163640 T/C cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7772486 0.641 rs2777485 chr6:146334377 G/A cg13319975 chr6:146136371 FBXO30 -0.68 -6.33 -0.49 4.17e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4853012 0.838 rs60705299 chr2:74345370 C/G cg19729930 chr2:74357872 NA 0.62 8.94 0.63 4.63e-15 Gestational age at birth (maternal effect); TGCT cis rs7267979 0.509 rs6115218 chr20:25566485 A/G cg03522245 chr20:25566470 NINL 0.8 8.62 0.61 2.57e-14 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg26116260 chr4:7069785 GRPEL1 1.07 9.88 0.66 2.5e-17 Monocyte percentage of white cells; TGCT cis rs9357506 1.000 rs60870663 chr6:46302975 T/A cg21115430 chr6:46460003 NA -0.27 -5.47 -0.44 2.43e-7 Body mass index; TGCT cis rs910316 1.000 rs175492 chr14:75545220 A/C cg11812906 chr14:75593930 NEK9 0.65 6.27 0.49 5.5e-9 Height; TGCT cis rs10504229 0.593 rs79615400 chr8:57988740 C/T cg02725872 chr8:58115012 NA -0.41 -4.96 -0.41 2.28e-6 Developmental language disorder (linguistic errors); TGCT cis rs4455778 1.000 rs4455778 chr7:49119500 G/T cg26309511 chr7:48887640 NA 0.45 5.22 0.42 7.27e-7 Lung cancer in never smokers; TGCT cis rs17122693 1.000 rs3015444 chr14:51085116 T/C cg04730355 chr14:51134070 SAV1 1.21 9.01 0.63 3.15e-15 Cognitive performance; TGCT cis rs514406 0.763 rs7535088 chr1:53215042 A/G cg22166914 chr1:53195759 ZYG11B -0.41 -7.06 -0.54 1.05e-10 Monocyte count; TGCT cis rs8180040 0.739 rs66539935 chr3:47025327 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.7 -0.62 1.7e-14 Colorectal cancer; TGCT cis rs904251 0.802 rs2646933 chr6:37402070 C/G cg25019722 chr6:37503610 NA -0.44 -5.01 -0.41 1.81e-6 Cognitive performance; TGCT cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg03060546 chr3:49711283 APEH 0.57 5.38 0.44 3.51e-7 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs1395 0.778 rs1439768 chr2:27389660 C/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.66 8.95 0.63 4.24e-15 Blood metabolite levels; TGCT cis rs9328448 0.882 rs7750233 chr6:7983040 A/G cg13863638 chr6:7199401 RREB1 0.19 4.49 0.37 1.64e-5 Coronary artery calcification; TGCT cis rs617219 0.698 rs72764983 chr5:78513806 T/C cg23987322 chr5:78407566 BHMT 0.37 4.86 0.4 3.52e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs655029 0.678 rs4952073 chr2:31457981 T/C cg14018959 chr2:31480232 EHD3 -0.36 -4.84 -0.4 3.76e-6 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs1245541 0.595 rs7072673 chr10:73865742 A/C cg10983208 chr10:73848320 SPOCK2 -0.26 -4.57 -0.38 1.18e-5 Insulin-like growth factors; TGCT cis rs10540 1.000 rs61876340 chr11:495699 A/C cg03352830 chr11:487213 PTDSS2 0.26 4.46 0.37 1.8e-5 Body mass index; TGCT cis rs28595532 0.920 rs114223775 chr4:119775091 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs12421382 0.659 rs57978015 chr11:109385473 T/C cg16359550 chr11:109292809 C11orf87 0.43 4.79 0.39 4.73e-6 Schizophrenia; TGCT cis rs10170846 1.000 rs10170846 chr2:223517705 C/G cg25565276 chr2:223520875 FARSB -0.78 -5.94 -0.47 2.67e-8 Schizophrenia (inflammation and infection response interaction); TGCT cis rs6450176 0.909 rs66872223 chr5:53292730 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7647973 1.000 rs9862534 chr3:49598064 A/G cg07636037 chr3:49044803 WDR6 0.61 5.11 0.42 1.17e-6 Menarche (age at onset); TGCT cis rs6500602 0.826 rs11076830 chr16:4460049 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 5.68 0.45 8.96e-8 Schizophrenia; TGCT cis rs17767294 0.541 rs72845050 chr6:27610070 A/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Parkinson's disease; TGCT cis rs11190604 1.000 rs10786596 chr10:102282126 C/A cg23241863 chr10:102295624 HIF1AN 0.7 5.39 0.44 3.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg18305652 chr10:134549665 INPP5A 0.31 5.23 0.43 6.87e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1062177 1.000 rs2964585 chr5:151141895 C/T cg00977110 chr5:151150581 G3BP1 0.41 4.62 0.38 9.52e-6 Preschool internalizing problems; TGCT cis rs4862307 0.720 rs12650935 chr4:184989565 G/A cg06737308 chr4:185021514 ENPP6 0.36 5.1 0.42 1.23e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs6450176 1.000 rs7736354 chr5:53297591 C/T ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.12 -0.42 1.15e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs4700695 0.614 rs251618 chr5:65215939 C/T cg21114390 chr5:65439923 SFRS12 0.64 4.89 0.4 3.07e-6 Facial morphology (factor 19); TGCT cis rs7666738 0.830 rs34890015 chr4:99023769 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.24 0.43 6.72e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6089584 0.924 rs6142906 chr20:60552554 G/C cg06108461 chr20:60628389 TAF4 -0.58 -8.16 -0.59 3.23e-13 Body mass index; TGCT cis rs9393777 0.513 rs9368451 chr6:26654333 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.767 rs10104728 chr8:11171300 A/G cg21775007 chr8:11205619 TDH 0.54 5.16 0.42 9.62e-7 Retinal vascular caliber; TGCT cis rs26868 0.742 rs26848 chr16:2263516 A/G cg25665528 chr16:2260870 C16orf79 -0.34 -5.71 -0.46 7.88e-8 Height; TGCT cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs28374715 0.532 rs28477406 chr15:41642036 C/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -15.82 -0.82 1.59e-31 Ulcerative colitis; TGCT cis rs6912958 0.967 rs6914299 chr6:88149176 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.63 -6.22 -0.49 7.06e-9 Monocyte percentage of white cells; TGCT cis rs13191362 1.000 rs67487119 chr6:163102657 A/C cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.96 0.67 1.56e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12701220 0.901 rs12701710 chr7:1090396 A/G cg27454412 chr7:1067447 C7orf50 0.49 4.7 0.39 6.86e-6 Bronchopulmonary dysplasia; TGCT cis rs4700695 0.668 rs153393 chr5:65428707 A/G cg21114390 chr5:65439923 SFRS12 -0.89 -7.95 -0.58 9.74e-13 Facial morphology (factor 19); TGCT cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg23982607 chr1:1823379 GNB1 -0.55 -8.57 -0.61 3.52e-14 Body mass index; TGCT cis rs9296661 0.868 rs4715241 chr6:51668490 C/T cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs7172809 0.599 rs75323552 chr15:77421943 A/T cg22256960 chr15:77711686 NA -0.49 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs36051895 0.632 rs10815171 chr9:5172567 G/A cg02405213 chr9:5042618 JAK2 -0.73 -9.91 -0.66 2.12e-17 Pediatric autoimmune diseases; TGCT cis rs651907 0.557 rs7651404 chr3:101393294 C/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs10089 0.953 rs10045113 chr5:127386631 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs11586313 0.507 rs3856026 chr1:152869763 T/C cg07796016 chr1:152779584 LCE1C -0.42 -4.71 -0.39 6.65e-6 Vitamin D levels; TGCT cis rs7267979 1.000 rs6076336 chr20:25319212 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9527 0.590 rs10883829 chr10:104840635 T/C cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs3858526 0.874 rs10838879 chr11:5950169 C/T cg13902645 chr11:5959945 NA -0.48 -5.0 -0.41 1.95e-6 DNA methylation (variation); TGCT cis rs7513165 1.000 rs7513165 chr1:204147186 C/T cg12731349 chr1:204159619 KISS1 -0.47 -5.47 -0.44 2.41e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs4319547 0.656 rs6488951 chr12:122873928 A/G cg08088222 chr12:122070432 ORAI1 0.25 4.49 0.37 1.58e-5 Body mass index; TGCT cis rs6754311 0.731 rs3769005 chr2:136603366 C/G cg07169764 chr2:136633963 MCM6 -0.68 -6.17 -0.48 9.08e-9 Mosquito bite size; TGCT cis rs6088590 0.901 rs6087631 chr20:33403509 T/C cg06115741 chr20:33292138 TP53INP2 0.65 5.45 0.44 2.66e-7 Coronary artery disease; TGCT cis rs539096 0.540 rs3011217 chr1:44303266 C/T cg12908607 chr1:44402522 ARTN 0.69 8.16 0.59 3.22e-13 Intelligence (multi-trait analysis); TGCT cis rs13191362 1.000 rs34714518 chr6:163080778 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.06 8.07 0.59 5.12e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1499614 0.901 rs2178742 chr7:66197799 G/A cg18252515 chr7:66147081 NA -1.23 -7.53 -0.56 9.12e-12 Gout; TGCT cis rs7659604 0.539 rs1507995 chr4:122748308 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.31 -0.43 4.84e-7 Type 2 diabetes; TGCT cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7223966 1.000 rs9901507 chr17:61765524 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.64 5.17 0.42 8.94e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg06238570 chr21:40685208 BRWD1 0.58 5.2 0.42 7.95e-7 Cognitive function; TGCT cis rs6724607 0.875 rs9630991 chr2:191432139 G/A cg27211696 chr2:191398769 TMEM194B 0.3 5.4 0.44 3.22e-7 Pulse pressure; TGCT cis rs7804356 0.734 rs13229947 chr7:26767430 T/C cg03456212 chr7:26904342 SKAP2 0.52 4.52 0.38 1.4e-5 Type 1 diabetes; TGCT cis rs9341808 0.718 rs3805920 chr6:80892745 T/C cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs9733 0.519 rs6700022 chr1:150670484 G/T cg04414720 chr1:150670196 GOLPH3L -0.35 -4.73 -0.39 5.88e-6 Tonsillectomy; TGCT trans rs11088226 0.681 rs2833903 chr21:33940819 C/T cg09050820 chr6:167586206 TCP10L2 0.8 7.25 0.55 3.95e-11 Gastritis; TGCT cis rs7945705 0.747 rs2742480 chr11:8993130 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.43 -4.61 -0.38 9.93e-6 Hemoglobin concentration; TGCT cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9902453 0.740 rs2244247 chr17:28110174 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg01017244 chr2:74357527 NA -0.37 -4.87 -0.4 3.37e-6 Gestational age at birth (maternal effect); TGCT cis rs7267979 0.706 rs6037069 chr20:25234166 C/T cg16686733 chr20:25566563 NINL 0.55 5.58 0.45 1.47e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9902453 0.845 rs2617865 chr17:28049804 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -7.27 -0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs6981523 0.517 rs13251510 chr8:10916974 A/G cg21775007 chr8:11205619 TDH -0.47 -4.66 -0.39 8.07e-6 Neuroticism; TGCT cis rs9393777 0.513 rs9379905 chr6:26630990 G/A cg15659132 chr6:26577336 NA -0.77 -5.48 -0.44 2.26e-7 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.640 rs28649792 chr4:119366463 A/C cg21605333 chr4:119757512 SEC24D 0.79 5.35 0.43 4.18e-7 Cannabis dependence symptom count; TGCT cis rs7524258 0.868 rs2412153 chr1:7272412 C/T cg07173049 chr1:7289937 CAMTA1 0.29 4.86 0.4 3.45e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs1552244 0.554 rs3732964 chr3:10048839 C/G cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs6489785 0.562 rs494632 chr12:121189116 C/T cg02419362 chr12:121203948 SPPL3 0.21 4.88 0.4 3.23e-6 Longevity;Allergic disease (asthma, hay fever or eczema); TGCT cis rs3796352 0.527 rs11714793 chr3:52924930 A/G cg11137980 chr3:52469226 SEMA3G 0.29 4.83 0.4 3.91e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7666738 0.830 rs35276471 chr4:99068691 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg02725872 chr8:58115012 NA -0.32 -4.78 -0.39 4.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs9399137 0.507 rs11757723 chr6:135291293 C/T cg24558204 chr6:135376177 HBS1L 0.46 4.65 0.39 8.46e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs478304 0.934 rs574483 chr11:65515277 A/G cg17480646 chr11:65405466 SIPA1 0.43 5.38 0.43 3.62e-7 Acne (severe); TGCT cis rs9818758 0.545 rs11717978 chr3:48969036 T/A cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9303401 0.659 rs72828726 chr17:56951217 C/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs7772486 0.875 rs1331639 chr6:146431869 A/G cg23711669 chr6:146136114 FBXO30 -0.87 -9.27 -0.64 7.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs950776 0.518 rs952215 chr15:78819153 C/T cg06917634 chr15:78832804 PSMA4 -0.95 -9.52 -0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs6938 0.662 rs12487 chr15:75136694 A/G cg10253484 chr15:75165896 SCAMP2 -0.6 -5.52 -0.44 1.93e-7 Breast cancer; TGCT cis rs992157 0.965 rs62182826 chr2:219148723 C/A cg00012203 chr2:219082015 ARPC2 0.78 8.39 0.6 9.39e-14 Colorectal cancer; TGCT cis rs904251 0.861 rs1757183 chr6:37484790 C/T cg08126542 chr6:37504118 NA 0.39 5.44 0.44 2.73e-7 Cognitive performance; TGCT cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs208520 0.690 rs4710564 chr6:66823478 A/G cg07460842 chr6:66804631 NA 0.94 7.67 0.57 4.32e-12 Exhaled nitric oxide output; TGCT trans rs7613875 0.620 rs3774734 chr3:50108792 C/A cg21659725 chr3:3221576 CRBN -0.67 -7.53 -0.56 9.05e-12 Body mass index; TGCT cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs7523654 1.000 rs7523654 chr1:115861265 A/G cg07790079 chr1:116021925 NA -0.37 -4.78 -0.39 4.81e-6 Schizophrenia; TGCT cis rs11587400 0.572 rs2268699 chr1:115227896 G/T cg12756093 chr1:115239321 AMPD1 0.32 4.52 0.38 1.42e-5 Autism; TGCT cis rs7208859 0.673 rs11649765 chr17:29233888 T/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7208859 0.623 rs11650973 chr17:29214045 G/A cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9902453 0.845 rs7218113 chr17:28372130 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs2880765 0.835 rs11856869 chr15:86029097 C/G cg13263323 chr15:86062960 AKAP13 -0.22 -4.7 -0.39 6.86e-6 Coronary artery disease; TGCT cis rs55665837 0.559 rs11023210 chr11:14422762 A/G cg19336497 chr11:14380999 RRAS2 0.33 5.1 0.42 1.23e-6 Vitamin D levels; TGCT cis rs9303542 0.559 rs12951076 chr17:46625109 T/C cg25032089 chr17:46643351 HOXB3 0.55 5.21 0.42 7.78e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs11190604 1.000 rs7079136 chr10:102292709 T/C cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6674176 0.593 rs6675620 chr1:44417630 C/T cg12908607 chr1:44402522 ARTN -0.67 -8.15 -0.59 3.4e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1903068 0.853 rs28680424 chr4:56009245 T/C cg09978860 chr4:56023921 NA 0.56 6.07 0.48 1.45e-8 Endometriosis; TGCT cis rs151997 1.000 rs151997 chr5:50233199 A/G cg06027927 chr5:50259733 NA -0.48 -5.0 -0.41 1.92e-6 Callous-unemotional behaviour; TGCT cis rs6460942 0.749 rs62448592 chr7:12435985 A/T cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs11098499 0.754 rs2964 chr4:120240131 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs1799949 1.000 rs11659028 chr17:41195025 T/A cg05368731 chr17:41323189 NBR1 1.1 10.91 0.7 7.88e-20 Menopause (age at onset); TGCT cis rs9921222 0.597 rs7193109 chr16:413523 T/G cg12437481 chr16:420112 MRPL28 -0.48 -4.75 -0.39 5.45e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs6933660 0.745 rs6912830 chr6:151743629 A/C cg10883421 chr6:151773342 RMND1;C6orf211 0.62 6.17 0.48 8.69e-9 Menarche (age at onset); TGCT cis rs6088590 0.561 rs6088528 chr20:33156742 G/A cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs7542091 0.666 rs7537070 chr1:210043565 A/G cg21951975 chr1:209979733 IRF6 0.6 6.1 0.48 1.24e-8 Monobrow; TGCT cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.13 -0.54 7.37e-11 Colorectal cancer; TGCT cis rs4304924 0.500 rs2281856 chr13:79207644 C/T cg05295671 chr13:79234353 RNF219 -0.73 -5.69 -0.45 8.7e-8 Large artery stroke; TGCT cis rs9796 0.717 rs2947494 chr15:41375741 C/T cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.76 -0.52 4.79e-10 Menopause (age at onset); TGCT cis rs9611565 0.802 rs132916 chr22:41806768 C/G cg06481639 chr22:41940642 POLR3H 0.57 5.24 0.43 6.79e-7 Vitiligo; TGCT cis rs58688157 0.921 rs12805435 chr11:612355 T/C cg16486109 chr11:613632 IRF7 0.35 5.18 0.42 8.82e-7 Systemic lupus erythematosus; TGCT cis rs4689388 0.890 rs1801206 chr4:6302707 C/T cg14416269 chr4:6271139 WFS1 0.41 5.63 0.45 1.14e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1867631 1.000 rs10889640 chr1:67127851 G/A cg13052034 chr1:66999238 SGIP1 0.56 4.78 0.39 4.85e-6 Menopause (age at onset); TGCT cis rs9611565 0.512 rs139572 chr22:42214532 C/T cg13695892 chr22:41940480 POLR3H -0.87 -8.24 -0.59 2.06e-13 Vitiligo; TGCT cis rs6570726 0.791 rs6570695 chr6:145911286 C/A cg23711669 chr6:146136114 FBXO30 0.86 9.28 0.64 7.13e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7542091 0.704 rs1883331 chr1:210043483 A/G cg22029157 chr1:209979665 IRF6 0.64 6.1 0.48 1.23e-8 Monobrow; TGCT cis rs1008375 0.900 rs4698625 chr4:17599500 G/T cg16339924 chr4:17578868 LAP3 0.84 6.77 0.52 4.62e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10207060 0.500 rs2118399 chr2:240683795 T/C cg07506560 chr2:240697449 NA 0.43 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs9467773 1.000 rs9986382 chr6:26550619 T/C cg15659132 chr6:26577336 NA 0.89 13.12 0.76 3.43e-25 Intelligence (multi-trait analysis); TGCT cis rs6430585 0.591 rs3098103 chr2:136656094 T/C cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs4325129 0.677 rs4540655 chr1:159478959 A/G cg07417683 chr1:159440267 NA 0.35 4.46 0.37 1.84e-5 Obesity-related traits; TGCT cis rs2594989 0.565 rs9848960 chr3:11601360 C/T cg00170343 chr3:11313890 ATG7 -0.72 -5.41 -0.44 3.15e-7 Circulating chemerin levels; TGCT cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs11250097 0.506 rs13281992 chr8:11309294 C/T cg21775007 chr8:11205619 TDH -0.57 -4.57 -0.38 1.16e-5 Neuroticism; TGCT cis rs425277 0.539 rs3128338 chr1:2046786 G/A cg03732007 chr1:2071316 PRKCZ -0.27 -5.9 -0.47 3.26e-8 Height; TGCT cis rs4372836 0.704 rs3190 chr2:29025479 A/G cg09522027 chr2:28974177 PPP1CB -0.7 -7.26 -0.55 3.68e-11 Body mass index; TGCT cis rs981844 0.857 rs41320045 chr4:154720615 A/T cg14289246 chr4:154710475 SFRP2 -1.01 -8.51 -0.61 4.9e-14 Response to statins (LDL cholesterol change); TGCT cis rs11098499 0.863 rs36040693 chr4:120477616 A/G cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg20637647 chr7:64974828 NA 0.95 5.8 0.46 5.3e-8 Diabetic kidney disease; TGCT cis rs986417 0.901 rs1955696 chr14:61028271 A/G cg27398547 chr14:60952738 C14orf39 1.13 10.75 0.69 1.94e-19 Gut microbiota (bacterial taxa); TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 4.98 0.41 2.08e-6 Prudent dietary pattern; TGCT cis rs939574 1.000 rs11552796 chr2:220108300 T/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.05 6.38 0.5 3.13e-9 Platelet distribution width; TGCT cis rs78487399 0.808 rs13405076 chr2:43735353 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.5 0.37 1.57e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7043114 0.507 rs10820971 chr9:95161740 G/C cg14311495 chr9:95764742 FGD3 -0.22 -4.52 -0.38 1.41e-5 Height; TGCT cis rs12935418 0.616 rs62054241 chr16:81004613 G/A cg07676361 chr16:80966860 NA -0.35 -4.56 -0.38 1.19e-5 Mean corpuscular volume; TGCT cis rs1799949 1.000 rs11653069 chr17:41283377 C/T cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs12136530 0.562 rs12125959 chr1:19735262 A/G cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs12540874 0.542 rs3807562 chr7:50566671 G/A cg18232548 chr7:50535776 DDC -0.35 -6.01 -0.48 1.89e-8 Systemic sclerosis; TGCT cis rs208520 0.690 rs74707865 chr6:66717352 A/G cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT trans rs57221529 0.709 rs4957056 chr5:570105 T/C cg25482853 chr8:67687455 SGK3 1.18 10.06 0.67 9.09e-18 Lung disease severity in cystic fibrosis; TGCT cis rs10788575 1.000 rs76774620 chr10:89751985 A/G cg03166508 chr10:89453226 PAPSS2 0.32 4.48 0.37 1.68e-5 Type 2 diabetes; TGCT cis rs7267979 1.000 rs6050559 chr20:25329915 A/G cg16686733 chr20:25566563 NINL 0.6 5.97 0.47 2.29e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6714788 0.565 rs7558817 chr2:100654482 C/A cg22139774 chr2:100720529 AFF3 -0.41 -6.5 -0.5 1.74e-9 Intelligence (multi-trait analysis); TGCT trans rs1005277 0.579 rs1621040 chr10:38497232 T/C cg17830980 chr10:43048298 ZNF37B -0.82 -10.2 -0.68 4.02e-18 Extrinsic epigenetic age acceleration; TGCT cis rs2120019 1.000 rs35577967 chr15:75354621 G/A cg09165964 chr15:75287851 SCAMP5 -1.18 -9.83 -0.66 3.33e-17 Blood trace element (Zn levels); TGCT trans rs2727020 0.615 rs4980435 chr11:49591576 G/A cg03929089 chr4:120376271 NA -0.74 -8.99 -0.63 3.54e-15 Coronary artery disease; TGCT cis rs1552244 1.000 rs3826 chr3:10141065 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs1420338 1.000 rs1420338 chr7:34143256 G/A cg01275685 chr7:34179230 BMPER -0.26 -4.75 -0.39 5.47e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs61990749 0.597 rs10136053 chr14:78155205 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.62 -0.38 9.57e-6 Fibroblast growth factor basic levels; TGCT cis rs789852 0.867 rs9288751 chr3:194316294 C/G cg18000598 chr3:194342907 TMEM44 0.88 5.69 0.46 8.48e-8 QT interval; TGCT cis rs1799949 1.000 rs11079056 chr17:41300799 C/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs12220238 0.908 rs11000937 chr10:75998785 A/C cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.91 0.58 1.21e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7246657 0.943 rs7248733 chr19:37996361 A/C cg18154014 chr19:37997991 ZNF793 0.7 4.86 0.4 3.52e-6 Coronary artery calcification; TGCT cis rs4853012 0.838 rs4429500 chr2:74345336 A/G cg20891558 chr2:74357851 NA 0.55 7.44 0.56 1.43e-11 Gestational age at birth (maternal effect); TGCT cis rs1371867 0.810 rs1618528 chr8:101259134 T/C cg00191853 chr8:101177733 SPAG1 0.22 4.5 0.37 1.53e-5 Atrioventricular conduction; TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg25151919 chr3:44754333 ZNF502 -0.39 -4.57 -0.38 1.15e-5 Depressive symptoms; TGCT cis rs3862030 0.810 rs5870 chr10:104239100 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.48 -4.61 -0.38 1e-5 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs433598 0.619 rs163264 chr16:20662769 A/G cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -4.94 -0.41 2.47e-6 Schizophrenia; TGCT cis rs2836974 0.602 rs2836987 chr21:40706594 C/T cg06238570 chr21:40685208 BRWD1 -0.82 -8.86 -0.62 7.17e-15 Cognitive function; TGCT cis rs68170813 0.641 rs77397573 chr7:107006892 G/A cg02696742 chr7:106810147 HBP1 -0.73 -5.95 -0.47 2.6e-8 Coronary artery disease; TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg16325326 chr1:53192061 ZYG11B 0.61 6.83 0.52 3.33e-10 Monocyte count; TGCT cis rs11779988 0.545 rs208764 chr8:17806270 G/A cg01800426 chr8:17659068 MTUS1 -0.64 -4.99 -0.41 2.02e-6 Breast cancer; TGCT cis rs3749237 1.000 rs6804655 chr3:49738945 C/T cg07636037 chr3:49044803 WDR6 0.65 5.75 0.46 6.7e-8 Resting heart rate; TGCT cis rs6754311 0.512 rs12998387 chr2:136507039 A/G cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Mosquito bite size; TGCT cis rs6087990 0.871 rs1007122 chr20:31346001 C/T cg13636640 chr20:31349939 DNMT3B 0.99 12.99 0.76 6.87e-25 Ulcerative colitis; TGCT cis rs950169 0.887 rs71395453 chr15:85113490 G/C cg17173187 chr15:85201210 NMB 0.47 4.93 0.4 2.62e-6 Schizophrenia; TGCT cis rs10654220 1 rs10654220 chr12:123703422 A/AGTT cg00376283 chr12:123451042 ABCB9 0.73 5.1 0.42 1.26e-6 Platelet count; TGCT cis rs7312933 0.558 rs11181483 chr12:42798384 G/C cg19980929 chr12:42632907 YAF2 0.42 5.94 0.47 2.67e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs539096 0.560 rs56201009 chr1:44098746 A/G cg12908607 chr1:44402522 ARTN -0.53 -5.63 -0.45 1.14e-7 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.887 rs4074838 chr7:100032665 G/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs2243480 0.764 rs2460423 chr7:65601216 A/T cg18252515 chr7:66147081 NA -1.21 -7.89 -0.58 1.36e-12 Diabetic kidney disease; TGCT cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7216064 0.953 rs1966410 chr17:65837215 T/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs12477438 0.501 rs11692336 chr2:99740606 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs7937682 0.564 rs7115263 chr11:111379054 C/A cg09085632 chr11:111637200 PPP2R1B 0.57 5.05 0.41 1.55e-6 Primary sclerosing cholangitis; TGCT cis rs6722750 0.933 rs4671555 chr2:64411137 C/G cg22352474 chr2:64371530 PELI1 -0.58 -5.16 -0.42 9.64e-7 Neuroticism; TGCT cis rs1580019 0.885 rs4460269 chr7:32496445 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg21672276 chr3:44754072 ZNF502 -0.54 -6.25 -0.49 5.94e-9 Depressive symptoms; TGCT cis rs6450176 1.000 rs5024170 chr5:53300827 C/A ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2404602 0.619 rs7342603 chr15:76982625 C/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs9611519 1.000 rs9611505 chr22:41540279 T/C cg03806693 chr22:41940476 POLR3H -0.67 -6.2 -0.49 7.87e-9 Neuroticism; TGCT cis rs79387448 0.745 rs17027428 chr2:103163175 G/A cg09003973 chr2:102972529 NA 0.92 5.89 0.47 3.39e-8 Gut microbiota (bacterial taxa); TGCT cis rs2153535 0.580 rs9505446 chr6:8448691 T/C cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg12667521 chr19:29218732 NA 0.51 6.05 0.48 1.57e-8 Methadone dose in opioid dependence; TGCT cis rs911555 0.713 rs2765051 chr14:103972379 T/C cg12935359 chr14:103987150 CKB 0.33 4.5 0.37 1.52e-5 Intelligence (multi-trait analysis); TGCT cis rs12479064 0.724 rs3087403 chr2:100058870 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -4.9 -0.4 2.99e-6 Chronic sinus infection; TGCT cis rs7666738 0.830 rs17027198 chr4:98991085 G/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs561341 1.000 rs117029332 chr17:30266085 C/G cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs1887596 0.663 rs2025413 chr13:27260914 G/A cg01312412 chr13:27282625 NA 0.3 5.48 0.44 2.32e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs10927875 0.722 rs1763605 chr1:16338925 T/G cg22431228 chr1:16359049 CLCNKA -0.26 -4.91 -0.4 2.79e-6 Dilated cardiomyopathy; TGCT cis rs7681440 0.904 rs2301134 chr4:90758945 A/G cg26578617 chr4:90757533 SNCA -0.48 -4.95 -0.41 2.35e-6 Dementia with Lewy bodies; TGCT cis rs6582630 0.539 rs35114325 chr12:38320886 G/T cg26384229 chr12:38710491 ALG10B -0.52 -4.5 -0.37 1.57e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs7582180 0.638 rs7581011 chr2:100954659 A/G cg14675211 chr2:100938903 LONRF2 -0.51 -5.02 -0.41 1.72e-6 Intelligence (multi-trait analysis); TGCT cis rs28785552 0.800 rs10853855 chr19:53232293 A/G cg10871876 chr19:53194124 ZNF83 0.54 7.4 0.55 1.79e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT trans rs28735056 0.933 rs499472 chr18:77589759 C/T cg05926928 chr17:57297772 GDPD1 -0.71 -7.64 -0.57 5.03e-12 Schizophrenia; TGCT cis rs12042938 0.935 rs751229 chr1:231768539 A/G cg04892437 chr1:231737901 TSNAX-DISC1 0.44 4.52 0.38 1.4e-5 Neuranatomic and neurocognitive phenotypes; TGCT cis rs2455799 0.573 rs924753 chr3:15706124 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.56 -0.38 1.21e-5 Mean platelet volume; TGCT cis rs3806843 0.607 rs246060 chr5:140324749 T/C cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs7824557 0.628 rs7831346 chr8:11193530 C/T cg21775007 chr8:11205619 TDH 0.7 6.86 0.52 2.93e-10 Retinal vascular caliber; TGCT cis rs11098499 0.954 rs11098524 chr4:120390032 A/G cg09307838 chr4:120376055 NA 0.69 5.85 0.46 4.13e-8 Corneal astigmatism; TGCT cis rs9435341 1.000 rs9435341 chr1:107616641 T/C cg09367891 chr1:107599246 PRMT6 -0.6 -5.38 -0.43 3.61e-7 Facial morphology (factor 21, depth of nasal alae); TGCT trans rs7726839 0.540 rs72707016 chr5:665148 A/G cg11887960 chr12:57824829 NA 1.15 9.91 0.66 2.07e-17 Obesity-related traits; TGCT cis rs68170813 0.559 rs4730226 chr7:106887274 A/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs6866344 0.697 rs17184281 chr5:178127563 G/A cg03877680 chr5:178157825 ZNF354A 0.72 5.61 0.45 1.27e-7 Neutrophil percentage of white cells; TGCT cis rs1008375 0.932 rs7677212 chr4:17675932 A/G cg18681998 chr4:17616180 MED28 -0.86 -8.49 -0.61 5.19e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17221829 0.733 rs72952851 chr11:89393495 A/G cg02982614 chr11:89391479 FOLH1B -0.27 -4.66 -0.39 7.89e-6 Anxiety in major depressive disorder; TGCT cis rs2303759 0.874 rs10411630 chr19:49891314 C/A cg22307029 chr19:49891270 CCDC155 0.54 5.09 0.42 1.29e-6 Multiple sclerosis; TGCT cis rs4925386 1.000 rs1889201 chr20:60923075 C/T cg06026331 chr20:60912101 LAMA5 -0.28 -5.14 -0.42 1.03e-6 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs10751667 1.000 rs7395632 chr11:958789 C/T cg06064525 chr11:970664 AP2A2 0.31 6.25 0.49 6.16e-9 Alzheimer's disease (late onset); TGCT cis rs1043515 0.748 rs11653487 chr17:36942631 A/G cg09592244 chr17:37024020 NA -0.49 -4.79 -0.39 4.77e-6 Height; TGCT cis rs9733 0.596 rs11803569 chr1:150664077 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs6882046 0.533 rs599402 chr5:88043656 G/C cg24804195 chr5:87968844 LOC645323 -0.57 -5.69 -0.46 8.66e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs1062177 0.826 rs2053063 chr5:151166764 T/C cg12924095 chr5:151150029 G3BP1 0.34 5.02 0.41 1.78e-6 Preschool internalizing problems; TGCT cis rs709400 0.633 rs8019578 chr14:103977724 A/G cg12935359 chr14:103987150 CKB -0.38 -5.7 -0.46 8.3e-8 Body mass index; TGCT cis rs394563 0.775 rs412894 chr6:149781175 G/A cg03678062 chr6:149772716 ZC3H12D -0.39 -4.83 -0.4 4.03e-6 Dupuytren's disease; TGCT cis rs6964587 1.000 rs7789492 chr7:91668854 C/T cg17063962 chr7:91808500 NA 0.88 9.63 0.65 9.8e-17 Breast cancer; TGCT cis rs921968 0.643 rs500317 chr2:219432953 G/C cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg23172400 chr8:95962367 TP53INP1 -0.36 -6.06 -0.48 1.54e-8 Type 2 diabetes; TGCT cis rs17767294 0.708 rs72847370 chr6:27849424 A/T cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs875971 1.000 rs2087647 chr7:65593188 C/A cg11764359 chr7:65958608 NA -0.57 -4.99 -0.41 2.03e-6 Aortic root size; TGCT cis rs17376456 1.000 rs12188453 chr5:93560807 G/T cg25358565 chr5:93447407 FAM172A -0.98 -7.65 -0.57 4.75e-12 Diabetic retinopathy; TGCT cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg08923669 chr16:420230 MRPL28 -0.54 -5.34 -0.43 4.24e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs9393777 0.513 rs9393737 chr6:26617306 A/G cg06675483 chr6:26987649 LOC100270746;C6orf41 0.48 4.59 0.38 1.06e-5 Intelligence (multi-trait analysis); TGCT cis rs2013441 1.000 rs2703785 chr17:20152418 C/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs4665809 0.590 rs2303894 chr2:26508187 A/G cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs2486012 1.000 rs2428957 chr1:44409048 A/G cg12908607 chr1:44402522 ARTN 0.74 5.92 0.47 2.96e-8 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.744 rs154657 chr16:89708096 A/G cg03388025 chr16:89894329 SPIRE2 0.34 5.21 0.42 7.59e-7 Vitiligo; TGCT trans rs1814175 0.647 rs10839394 chr11:49844747 T/C cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs6840360 0.642 rs7680236 chr4:152409601 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs12210905 0.920 rs9348763 chr6:27302919 G/C cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs137699 1.000 rs2049986 chr22:39756854 C/G cg11247378 chr22:39784982 NA 0.5 5.84 0.46 4.38e-8 IgG glycosylation; TGCT cis rs7043114 0.525 rs7850432 chr9:95130510 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.58 -0.45 1.47e-7 Height; TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg26354017 chr1:205819088 PM20D1 0.68 9.51 0.65 2e-16 Menarche (age at onset); TGCT cis rs9790314 0.586 rs73021449 chr3:161128941 G/A cg03342759 chr3:160939853 NMD3 -0.55 -5.66 -0.45 9.91e-8 Morning vs. evening chronotype; TGCT cis rs10489202 0.632 rs202265 chr1:167990231 G/C cg24449463 chr1:168025552 DCAF6 -0.6 -7.15 -0.54 6.45e-11 Schizophrenia; TGCT cis rs7264396 0.580 rs6119655 chr20:34412049 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.74 -0.39 5.7e-6 Total cholesterol levels; TGCT cis rs899997 1.000 rs11072794 chr15:79006582 A/G cg00061860 chr15:78953028 NA -0.25 -4.59 -0.38 1.05e-5 Coronary artery disease or large artery stroke; TGCT cis rs7666738 0.791 rs7377018 chr4:99034962 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs72615157 0.561 rs113844570 chr7:99873778 A/C cg00814883 chr7:100076585 TSC22D4 -0.59 -5.7 -0.46 8.45e-8 Lung function (FEV1/FVC); TGCT cis rs2033711 0.905 rs893186 chr19:58969179 C/A cg12042659 chr19:58951599 ZNF132 0.56 4.94 0.41 2.51e-6 Uric acid clearance; TGCT trans rs2727020 0.658 rs1851992 chr11:49438110 C/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.23 -0.59 2.15e-13 Coronary artery disease; TGCT cis rs700590 0.723 rs160043 chr5:88115885 T/A cg22951263 chr5:87985283 NA 0.55 5.33 0.43 4.45e-7 Educational attainment (years of education); TGCT cis rs9894429 0.608 rs8477 chr17:79618059 C/T cg18240062 chr17:79603768 NPLOC4 0.56 4.86 0.4 3.49e-6 Eye color traits; TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg27535305 chr1:53392650 SCP2 -0.25 -5.06 -0.41 1.47e-6 Monocyte count; TGCT cis rs7666738 0.519 rs28539191 chr4:98821552 C/T cg18180107 chr4:99064573 C4orf37 0.54 4.61 0.38 9.77e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.754 rs28663627 chr11:50048829 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs12477438 1.000 rs73963398 chr2:99887025 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.82 -6.44 -0.5 2.4e-9 Chronic sinus infection; TGCT cis rs7246657 0.722 rs1531549 chr19:38088009 T/C cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.71e-6 Coronary artery calcification; TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.95 0.41 2.35e-6 Prudent dietary pattern; TGCT cis rs13256369 1.000 rs9329165 chr8:8576642 C/T cg17143192 chr8:8559678 CLDN23 -0.57 -5.39 -0.44 3.48e-7 Obesity-related traits; TGCT cis rs10056811 0.527 rs55798253 chr5:74380957 A/G cg19683494 chr5:74908142 NA 0.63 5.06 0.41 1.49e-6 Coronary artery disease; TGCT cis rs597539 0.652 rs501799 chr11:68631240 G/T cg06112835 chr11:68658793 MRPL21 0.46 8.1 0.59 4.37e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs79349575 0.783 rs962272 chr17:46978283 A/G cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs8017423 0.967 rs4904663 chr14:90729565 G/T cg04374321 chr14:90722782 PSMC1 0.78 7.86 0.58 1.59e-12 Mortality in heart failure; TGCT cis rs7666738 0.830 rs60007031 chr4:98824753 G/C cg18180107 chr4:99064573 C4orf37 0.55 5.25 0.43 6.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9644630 0.870 rs4244453 chr8:19359711 G/A cg01280390 chr8:19363452 CSGALNACT1 0.27 4.66 0.39 8.01e-6 Oropharynx cancer; TGCT cis rs7120118 0.517 rs3758668 chr11:47270775 C/T cg13308137 chr11:47528955 CUGBP1 0.33 5.25 0.43 6.32e-7 HDL cholesterol; TGCT cis rs12210905 0.688 rs72845232 chr6:27428126 T/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs17331151 0.573 rs76029595 chr3:52868523 C/T cg11137980 chr3:52469226 SEMA3G 0.29 5.14 0.42 1.04e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3087591 0.960 rs12942397 chr17:29462498 C/A cg24425628 chr17:29625626 OMG;NF1 0.48 7.4 0.55 1.77e-11 Hip circumference; TGCT cis rs9393692 0.875 rs12526215 chr6:26262916 T/C cg00631329 chr6:26305371 NA -0.44 -6.6 -0.51 1.1e-9 Educational attainment; TGCT cis rs9435341 0.965 rs1762482 chr1:107599002 A/C cg09367891 chr1:107599246 PRMT6 -0.63 -5.52 -0.44 1.89e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs477895 0.652 rs72920332 chr11:63947071 G/T cg04317338 chr11:64019027 PLCB3 0.8 6.61 0.51 1.01e-9 Mean platelet volume; TGCT cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs2836974 0.931 rs12151994 chr21:40690397 A/C cg11890956 chr21:40555474 PSMG1 1.13 11.5 0.72 2.86e-21 Cognitive function; TGCT cis rs3785574 0.924 rs2727292 chr17:61893747 A/G cg11494091 chr17:61959527 GH2 0.43 7.4 0.55 1.82e-11 Height; TGCT cis rs4730250 0.802 rs77936580 chr7:106946343 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Osteoarthritis; TGCT cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg26818010 chr10:134567672 INPP5A -0.38 -5.37 -0.43 3.66e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3617 0.625 rs3774364 chr3:52863605 G/A cg10802521 chr3:52805072 NEK4 -0.57 -6.56 -0.51 1.34e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.519 rs11732209 chr4:98801643 A/G cg05340658 chr4:99064831 C4orf37 0.51 5.66 0.45 9.78e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.502 rs11610978 chr12:38356957 C/G cg26384229 chr12:38710491 ALG10B 0.78 6.98 0.53 1.56e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs6570726 0.935 rs369458 chr6:145812809 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.16e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.772 rs4240875 chr1:154885782 G/A cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs9311474 0.539 rs12489828 chr3:52567014 G/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.56 -5.49 -0.44 2.13e-7 Electroencephalogram traits; TGCT cis rs1499614 1.000 rs2659911 chr7:66158420 G/A cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs7258465 1.000 rs34171762 chr19:18559410 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs9914988 1.000 rs9916866 chr17:27183155 C/G cg20469991 chr17:27169893 C17orf63 0.69 5.05 0.41 1.51e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9807989 0.765 rs13424006 chr2:102967236 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs3862030 0.839 rs2274351 chr10:104264107 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.52 -4.99 -0.41 2e-6 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs4820539 1.000 rs4822360 chr22:23482460 A/G cg21100191 chr22:23484243 RTDR1 0.9 10.72 0.69 2.2e-19 Bone mineral density; TGCT trans rs10156309 0.555 rs16928749 chr8:63273943 C/T cg03123541 chr1:95699097 RWDD3 0.75 6.72 0.52 5.9e-10 Allergic rhinitis; TGCT cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg26531700 chr6:26746687 NA 0.51 4.61 0.38 9.86e-6 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.609 rs6087783 chr20:30421224 T/G cg13852791 chr20:30311386 BCL2L1 0.84 7.59 0.56 6.79e-12 Mean corpuscular hemoglobin; TGCT cis rs992157 0.717 rs3817266 chr2:219142594 C/T cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs2760061 0.819 rs708115 chr1:228198046 C/T cg18477163 chr1:228402036 OBSCN 0.34 7.19 0.54 5.33e-11 Diastolic blood pressure; TGCT cis rs11105298 0.891 rs10858898 chr12:89922111 A/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs3733585 0.726 rs4306953 chr4:9955776 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1008375 1.000 rs2058337 chr4:17678649 C/T cg18681998 chr4:17616180 MED28 0.91 10.02 0.67 1.12e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4975709 0.610 rs4975704 chr5:1859807 C/A cg14773178 chr5:1868261 NA 0.34 5.62 0.45 1.21e-7 Cardiovascular disease risk factors; TGCT cis rs2204008 0.805 rs12146846 chr12:37985847 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs7586879 0.929 rs6545807 chr2:25124358 C/T cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs17345786 0.520 rs13062677 chr3:101305078 G/A cg12386194 chr3:101231763 SENP7 0.52 5.52 0.44 1.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9549367 0.713 rs556990 chr13:113845059 T/C cg00898013 chr13:113819073 PROZ 0.53 7.2 0.54 5.17e-11 Platelet distribution width; TGCT trans rs561341 1.000 rs530209 chr17:30315287 A/G cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs7336332 0.598 rs75439483 chr13:28010512 A/G cg22138327 chr13:27999177 GTF3A 0.8 5.97 0.47 2.35e-8 Weight; TGCT cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg01802117 chr1:53393560 SCP2 -0.44 -5.52 -0.44 1.86e-7 Monocyte count; TGCT cis rs2204008 0.837 rs12366727 chr12:38365748 A/C cg26384229 chr12:38710491 ALG10B 0.83 7.24 0.55 4.15e-11 Bladder cancer; TGCT cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg02725872 chr8:58115012 NA -0.4 -5.23 -0.42 7.07e-7 Developmental language disorder (linguistic errors); TGCT cis rs9420 0.961 rs499188 chr11:57434122 C/A cg23127183 chr11:57508653 C11orf31 -0.45 -4.56 -0.38 1.23e-5 Schizophrenia; TGCT cis rs7705042 0.865 rs11739961 chr5:141508488 A/C cg23435118 chr5:141488016 NDFIP1 -0.2 -4.43 -0.37 2.01e-5 Asthma; TGCT cis rs151997 0.925 rs27286 chr5:50196324 G/T cg06027927 chr5:50259733 NA 0.48 4.95 0.41 2.41e-6 Callous-unemotional behaviour; TGCT cis rs6088590 0.965 rs6087619 chr20:33288511 C/G cg06115741 chr20:33292138 TP53INP2 0.67 5.71 0.46 8.07e-8 Coronary artery disease; TGCT cis rs611744 0.647 rs6981420 chr8:109266694 T/G cg21045802 chr8:109455806 TTC35 0.7 7.23 0.54 4.3e-11 Dupuytren's disease; TGCT cis rs7917772 0.503 rs61871067 chr10:104295382 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 7.86 0.58 1.59e-12 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs853679 0.517 rs35512245 chr6:28079953 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT trans rs9388451 0.868 rs10457467 chr6:126045148 T/A cg05039488 chr6:79577232 IRAK1BP1 -0.76 -8.22 -0.59 2.35e-13 Brugada syndrome; TGCT cis rs12497850 0.931 rs9755490 chr3:48871664 A/C cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs72627509 0.638 rs78272732 chr4:57870537 T/A cg26694713 chr4:57773883 REST 0.62 4.63 0.38 9.06e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6598955 0.671 rs57386998 chr1:26569821 G/A cg04990556 chr1:26633338 UBXN11 0.64 5.11 0.42 1.19e-6 Obesity-related traits; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg16325326 chr1:53192061 ZYG11B -0.61 -6.93 -0.53 2.05e-10 Monocyte count; TGCT cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.6 -0.65 1.15e-16 Platelet count; TGCT cis rs35160687 0.901 rs13017338 chr2:86501553 T/C cg12542933 chr2:85804724 VAMP8 0.39 4.7 0.39 6.7e-6 Night sleep phenotypes; TGCT cis rs10086908 0.669 rs1456310 chr8:128052433 C/T cg26031047 chr8:127570723 FAM84B 0.5 4.91 0.4 2.78e-6 Prostate cancer (SNP x SNP interaction);Prostate cancer; TGCT cis rs9952991 0.883 rs2847260 chr18:12775591 C/T cg09945482 chr18:12777974 NA 0.5 4.75 0.39 5.61e-6 Inflammatory skin disease; TGCT cis rs36051895 0.659 rs67006981 chr9:5070401 A/G cg02405213 chr9:5042618 JAK2 -0.74 -9.47 -0.65 2.46e-16 Pediatric autoimmune diseases; TGCT cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg13393036 chr8:95962371 TP53INP1 -0.65 -8.88 -0.62 6.27e-15 Type 2 diabetes; TGCT cis rs1577917 1.000 rs35419329 chr6:86702291 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs2242194 0.816 rs6671688 chr1:154994265 T/C cg12436631 chr1:155007014 DCST1;DCST2 0.26 7.21 0.54 4.84e-11 Schizophrenia; TGCT cis rs903263 0.965 rs11163906 chr1:84594533 T/C cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.73e-6 Breast cancer (male); TGCT cis rs9611565 0.592 rs6519270 chr22:42078666 A/G cg06481639 chr22:41940642 POLR3H 0.6 5.18 0.42 8.77e-7 Vitiligo; TGCT cis rs9913156 0.894 rs35741745 chr17:4620897 A/G cg00122941 chr17:4613640 ARRB2 0.94 8.09 0.59 4.57e-13 Lymphocyte counts; TGCT cis rs11031096 0.542 rs2412338 chr11:3977521 G/T cg18678763 chr11:4115507 RRM1 -0.41 -5.09 -0.42 1.27e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs864643 1.000 rs634338 chr3:39564243 C/T cg14968361 chr3:39543547 MOBP -0.48 -4.48 -0.37 1.68e-5 Attention deficit hyperactivity disorder; TGCT cis rs1018836 0.884 rs7823461 chr8:91581075 T/C cg16814680 chr8:91681699 NA -0.89 -9.58 -0.65 1.3e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1670533 1.000 rs1670533 chr4:1078187 G/A cg20887711 chr4:1340912 KIAA1530 0.7 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs7208859 0.673 rs61223749 chr17:29163747 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs885389 0.924 rs7957882 chr12:131617417 G/T cg07124762 chr12:131619285 GPR133 -0.31 -6.5 -0.5 1.72e-9 RR interval (heart rate); TGCT cis rs6750047 0.526 rs464603 chr2:38318131 G/C cg07380506 chr2:38303506 CYP1B1 0.59 5.47 0.44 2.37e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs5769765 0.773 rs9616382 chr22:50312979 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs782590 0.902 rs782600 chr2:55848040 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.91 0.53 2.23e-10 Metabolic syndrome; TGCT cis rs3784262 0.934 rs7164408 chr15:58259336 A/G cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.7 -0.57 3.78e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6740322 0.895 rs10172375 chr2:43572047 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.24 -0.49 6.33e-9 Coronary artery disease; TGCT cis rs9467773 1.000 rs1056667 chr6:26510564 T/C cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT cis rs7552404 1.000 rs12126607 chr1:76217097 G/A cg22875332 chr1:76189707 ACADM 0.76 9.2 0.64 1.1e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7829975 0.591 rs12677543 chr8:8644274 G/C cg15556689 chr8:8085844 FLJ10661 0.72 6.52 0.51 1.63e-9 Mood instability; TGCT cis rs2072499 1.000 rs2540173 chr1:156188214 A/G cg24450063 chr1:156163899 SLC25A44 1.14 16.5 0.83 4.43e-33 Testicular germ cell tumor; TGCT cis rs7809950 0.871 rs11771278 chr7:107285925 C/T cg23024343 chr7:107201750 COG5 0.29 4.77 0.39 4.99e-6 Coronary artery disease; TGCT cis rs2456568 0.741 rs9633811 chr11:93628327 A/G cg14291919 chr11:93583693 C11orf90 0.41 4.53 0.38 1.34e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10782582 0.593 rs12132750 chr1:76136222 A/G cg22875332 chr1:76189707 ACADM -0.54 -6.21 -0.49 7.36e-9 Daytime sleep phenotypes; TGCT cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg17554472 chr22:41940697 POLR3H -0.44 -4.6 -0.38 1.03e-5 Vitiligo; TGCT cis rs6912958 0.559 rs369674 chr6:88043402 C/G cg04972856 chr6:88032051 C6orf162;GJB7 -0.4 -4.7 -0.39 6.83e-6 Monocyte percentage of white cells; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg24675658 chr1:53192096 ZYG11B -0.7 -7.9 -0.58 1.26e-12 Monocyte count; TGCT cis rs1371867 0.846 rs1660327 chr8:101292206 A/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs10089 1.000 rs13356473 chr5:127478250 T/G cg19767477 chr5:127420684 SLC12A2 -0.43 -4.56 -0.38 1.21e-5 Ileal carcinoids; TGCT cis rs2300747 0.872 rs11588376 chr1:117072524 T/C cg26677431 chr1:117075710 CD58 -0.23 -4.46 -0.37 1.78e-5 Primary biliary cholangitis;Multiple sclerosis; TGCT cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.08 0.42 1.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs926938 0.618 rs3121506 chr1:115363207 T/G cg12756093 chr1:115239321 AMPD1 0.42 6.0 0.47 2.04e-8 Autism; TGCT cis rs3820068 0.705 rs4646109 chr1:15817319 T/C cg05660106 chr1:15850417 CASP9 1.15 14.12 0.79 1.41e-27 Systolic blood pressure; TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs4808199 0.895 rs8105984 chr19:19374068 T/C cg03709012 chr19:19516395 GATAD2A 0.8 6.04 0.48 1.66e-8 Nonalcoholic fatty liver disease; TGCT cis rs9486719 0.843 rs3860231 chr6:97036563 G/A cg18709589 chr6:96969512 KIAA0776 -0.78 -6.38 -0.5 3.24e-9 Migraine;Coronary artery disease; TGCT cis rs892961 0.899 rs72896163 chr17:75412525 C/T cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs7267979 0.966 rs2424714 chr20:25418681 T/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10411936 1.000 rs11878602 chr19:16555153 A/C cg19006008 chr19:16999768 F2RL3 -0.27 -4.73 -0.39 5.95e-6 White blood cell count;Multiple sclerosis; TGCT cis rs10501293 0.746 rs10768908 chr11:43020214 C/T cg03447554 chr11:43094025 NA 0.43 6.14 0.48 1.03e-8 Cognitive performance; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg11905131 chr22:24372483 LOC391322 -0.95 -11.13 -0.71 2.26e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9329289 1.000 rs9329289 chr10:2542389 A/G cg15501526 chr10:2543763 NA 0.39 4.91 0.4 2.8e-6 Age-related hearing impairment; TGCT cis rs66887589 0.616 rs10032299 chr4:120206419 C/T cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.14e-5 Diastolic blood pressure; TGCT cis rs9393692 0.905 rs989134 chr6:26336224 A/C cg00631329 chr6:26305371 NA -0.4 -5.81 -0.46 4.97e-8 Educational attainment; TGCT cis rs6835098 1.000 rs6814857 chr4:174082805 T/A cg08422745 chr4:174089978 GALNT7 -0.91 -10.41 -0.68 1.31e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg03303774 chr4:1407052 NA -0.32 -4.88 -0.4 3.21e-6 Obesity-related traits; TGCT cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg03517284 chr6:25882590 NA 0.78 8.11 0.59 4.26e-13 Blood metabolite levels; TGCT cis rs7666738 0.800 rs28427190 chr4:98989106 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.658 rs9403737 chr6:145962193 G/T cg23711669 chr6:146136114 FBXO30 0.88 9.78 0.66 4.39e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs67311347 1.000 rs11714032 chr3:40431605 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs1472147 1.000 rs3736609 chr7:128509319 G/A cg05395852 chr7:128750384 NA 0.17 4.58 0.38 1.11e-5 Calcium levels; TGCT cis rs9733 0.527 rs11204694 chr1:150653391 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.13 0.42 1.09e-6 Tonsillectomy; TGCT cis rs281408 0.559 rs204248 chr19:49216224 G/C cg13540341 chr19:49222985 MAMSTR 0.47 7.23 0.54 4.25e-11 Urinary metabolites (H-NMR features); TGCT cis rs1008375 0.932 rs4698628 chr4:17608620 A/G cg18681998 chr4:17616180 MED28 0.98 10.43 0.68 1.17e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9393692 0.578 rs806795 chr6:26205293 G/A cg05868516 chr6:26286170 HIST1H4H 0.51 4.87 0.4 3.27e-6 Educational attainment; TGCT cis rs6840360 0.554 rs58751443 chr4:152709905 A/G cg17479576 chr4:152424074 FAM160A1 -0.51 -5.22 -0.42 7.21e-7 Intelligence (multi-trait analysis); TGCT cis rs7617773 0.780 rs77044321 chr3:48349314 C/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs7666738 0.791 rs1426674 chr4:98924247 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7524258 0.867 rs916392 chr1:7271930 T/C cg07173049 chr1:7289937 CAMTA1 0.31 5.24 0.43 6.74e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs2228479 0.850 rs17226428 chr16:89842884 T/A cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs10114408 0.959 rs10126012 chr9:96634101 C/T cg13679303 chr9:96623674 NA -0.35 -4.58 -0.38 1.1e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6951245 0.554 rs79367977 chr7:1152657 G/A cg03188948 chr7:1209495 NA 0.5 5.23 0.43 6.99e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs950169 0.840 rs2896002 chr15:84945121 A/G cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs734999 0.588 rs2764841 chr1:2529360 G/A cg18854424 chr1:2615690 NA -0.5 -5.9 -0.47 3.25e-8 Ulcerative colitis; TGCT cis rs6089584 0.528 rs4925335 chr20:60627034 G/A cg06108461 chr20:60628389 TAF4 -0.43 -5.2 -0.42 7.98e-7 Body mass index; TGCT cis rs1797081 0.646 rs7090256 chr10:16851949 T/G cg14835575 chr10:16859367 RSU1 0.45 5.46 0.44 2.47e-7 Platelet distribution width; TGCT cis rs1577917 0.959 rs12201739 chr6:86720739 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs9291683 0.530 rs6449196 chr4:9973660 C/T cg00071950 chr4:10020882 SLC2A9 -0.65 -8.23 -0.59 2.24e-13 Bone mineral density; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg04234412 chr22:24373322 LOC391322 -0.92 -11.65 -0.72 1.19e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4285028 0.948 rs34837785 chr3:121657776 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs12477438 0.520 rs2632277 chr2:99778985 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 18.53 0.86 1.57e-37 Chronic sinus infection; TGCT cis rs6964587 0.839 rs17731846 chr7:91440342 A/G cg17063962 chr7:91808500 NA 0.87 9.22 0.64 9.51e-16 Breast cancer; TGCT cis rs6998277 0.830 rs7017839 chr8:103610769 G/C cg10187029 chr8:103597600 NA 0.56 8.73 0.62 1.41e-14 Migraine; TGCT cis rs12643440 0.538 rs10489117 chr4:17145568 G/T cg22650099 chr4:17144496 NA -0.49 -5.03 -0.41 1.66e-6 Metabolite levels (Pyroglutamine); TGCT cis rs10114408 0.959 rs2153062 chr9:96653752 A/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs8014204 0.935 rs2300596 chr14:75353855 C/T cg06637938 chr14:75390232 RPS6KL1 0.7 6.76 0.52 4.74e-10 Caffeine consumption; TGCT cis rs71435601 0.600 rs479545 chr2:21389897 T/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs17401966 0.838 rs8019 chr1:10366487 T/G cg19773385 chr1:10388646 KIF1B -0.23 -5.04 -0.41 1.6e-6 Hepatocellular carcinoma; TGCT cis rs5750830 0.594 rs6001587 chr22:39819008 T/C cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.938 rs113642700 chr7:1105654 C/T cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4713118 0.628 rs9295740 chr6:27689502 G/A cg10876282 chr6:28092338 ZSCAN16 0.64 5.29 0.43 5.39e-7 Parkinson's disease; TGCT cis rs2832077 0.527 rs2738953 chr21:30238363 G/C cg24692254 chr21:30365293 RNF160 0.59 4.98 0.41 2.04e-6 Cognitive test performance; TGCT cis rs6121246 0.559 rs6060922 chr20:30333909 C/T cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT trans rs1005277 0.579 rs2504148 chr10:38400788 A/G cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs533581 0.866 rs865102 chr16:88969969 A/G cg16701003 chr16:89028210 CBFA2T3 0.35 4.78 0.39 4.93e-6 Social autistic-like traits; TGCT cis rs7017914 0.902 rs34882924 chr8:71566308 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.5 -4.68 -0.39 7.37e-6 Bone mineral density; TGCT cis rs7249142 0.573 rs2238668 chr19:19282597 A/G cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.55 0.45 1.64e-7 IgG glycosylation; TGCT cis rs4906332 1.000 rs12889703 chr14:103872951 T/A cg26031613 chr14:104095156 KLC1 -0.51 -4.65 -0.39 8.49e-6 Coronary artery disease; TGCT cis rs453301 0.652 rs2043129 chr8:8825504 C/G cg11995313 chr8:8860691 ERI1 -0.56 -4.95 -0.41 2.35e-6 Joint mobility (Beighton score); TGCT cis rs72781680 0.716 rs2551325 chr2:23979729 C/T cg08917208 chr2:24149416 ATAD2B 0.75 5.04 0.41 1.59e-6 Lymphocyte counts; TGCT cis rs854765 0.583 rs12452219 chr17:17829423 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.77 0.57 2.58e-12 Total body bone mineral density; TGCT cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg09222892 chr1:25734099 RHCE -0.42 -6.65 -0.51 8.38e-10 Erythrocyte sedimentation rate; TGCT cis rs1218582 0.741 rs11264281 chr1:154867221 A/G cg06221963 chr1:154839813 KCNN3 -0.82 -15.75 -0.82 2.27e-31 Prostate cancer; TGCT cis rs4819052 1.000 rs2297286 chr21:46707897 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 5.49 0.44 2.17e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs478304 0.651 rs11537193 chr11:65500003 A/C cg27068330 chr11:65405492 SIPA1 -0.94 -9.4 -0.65 3.49e-16 Acne (severe); TGCT cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs8177253 0.665 rs9869257 chr3:133451412 G/T cg01448562 chr3:133502909 NA -0.26 -5.06 -0.41 1.49e-6 Iron status biomarkers; TGCT cis rs593982 0.925 rs3953806 chr11:65505153 C/T cg08755490 chr11:65554678 OVOL1 -1.48 -10.77 -0.7 1.68e-19 Atopic dermatitis; TGCT cis rs9788721 0.836 rs72738736 chr15:78765122 G/T cg18825076 chr15:78729989 IREB2 -0.32 -5.02 -0.41 1.76e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs2204008 0.515 rs11495471 chr12:38027178 G/A cg26384229 chr12:38710491 ALG10B 0.85 7.62 0.56 5.71e-12 Bladder cancer; TGCT cis rs7267979 1.000 rs2184000 chr20:25395878 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7027203 0.663 rs4428726 chr9:96623559 T/G cg14396892 chr9:96623032 NA -0.28 -5.71 -0.46 7.98e-8 DNA methylation (variation); TGCT cis rs9807989 0.507 rs1420094 chr2:103015687 C/T cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs12776158 1.000 rs12776158 chr10:71218094 T/C cg12610070 chr10:71211762 TSPAN15 -0.59 -5.17 -0.42 9.16e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs6840360 1.000 rs6818667 chr4:152598698 T/C cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs9372253 0.967 rs1055301 chr6:110713042 A/G cg19196401 chr6:110721138 DDO -0.48 -7.05 -0.53 1.1e-10 Platelet distribution width; TGCT cis rs13393800 0.536 rs2697801 chr2:233382123 G/A cg26635044 chr2:233757626 NGEF 0.18 5.0 0.41 1.92e-6 Height; TGCT cis rs11098499 0.691 rs12502524 chr4:120271414 G/A cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.05e-7 Corneal astigmatism; TGCT cis rs7824557 0.603 rs6995404 chr8:11182148 C/G cg21775007 chr8:11205619 TDH 0.62 6.14 0.48 1.03e-8 Retinal vascular caliber; TGCT cis rs4766566 0.590 rs4766567 chr12:111707556 G/A cg10833066 chr12:111807467 FAM109A 0.33 4.65 0.39 8.5e-6 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs17270561 0.887 rs9358870 chr6:25719210 T/C cg15022984 chr6:26056706 HIST1H1C -0.7 -4.62 -0.38 9.28e-6 Iron status biomarkers; TGCT cis rs62380364 0.805 rs2362109 chr5:88148041 C/T cg22951263 chr5:87985283 NA -0.48 -4.62 -0.38 9.39e-6 Intelligence (multi-trait analysis); TGCT cis rs11719291 0.833 rs11709246 chr3:48859498 G/A cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 Cognitive function; TGCT cis rs6060960 0.502 rs15817 chr20:30193538 A/G cg21427119 chr20:30132790 HM13 -0.38 -5.63 -0.45 1.14e-7 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg13695892 chr22:41940480 POLR3H 0.93 8.53 0.61 4.2e-14 Vitiligo; TGCT cis rs6988636 0.710 rs73339623 chr8:124140288 A/G cg22384356 chr8:124195192 FAM83A -0.42 -4.59 -0.38 1.06e-5 Urinary uromodulin levels; TGCT cis rs796364 0.951 rs281793 chr2:200847990 G/A cg17644776 chr2:200775616 C2orf69 0.31 4.87 0.4 3.37e-6 Schizophrenia; TGCT cis rs3820068 0.608 rs11544523 chr1:15904318 C/T cg05660106 chr1:15850417 CASP9 1.16 14.26 0.79 6.71e-28 Systolic blood pressure; TGCT cis rs4788570 0.615 rs4788822 chr16:71681515 A/G cg06353428 chr16:71660113 MARVELD3 1.52 12.45 0.75 1.36e-23 Intelligence (multi-trait analysis); TGCT cis rs2070488 0.662 rs7375040 chr3:38469116 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.72 5.94 0.47 2.7e-8 Electrocardiographic conduction measures; TGCT cis rs514406 0.668 rs1672911 chr1:53340320 T/C cg16325326 chr1:53192061 ZYG11B 0.57 6.26 0.49 5.62e-9 Monocyte count; TGCT cis rs1857353 1.000 rs58248429 chr1:75923753 G/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs595982 0.501 rs112370206 chr19:49396623 C/T cg21252483 chr19:49399788 TULP2 -0.3 -5.05 -0.41 1.54e-6 Red cell distribution width; TGCT cis rs7666738 0.830 rs34135615 chr4:99001325 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.724 rs2955371 chr17:17967397 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.77 -7.93 -0.58 1.1e-12 Total body bone mineral density; TGCT cis rs763014 1.000 rs763014 chr16:675680 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.4 -0.6 8.47e-14 Height; TGCT cis rs1005277 0.540 rs116205409 chr10:38478970 G/A cg25427524 chr10:38739819 LOC399744 -0.41 -8.54 -0.61 4.04e-14 Extrinsic epigenetic age acceleration; TGCT cis rs854765 0.547 rs28537385 chr17:17902135 G/A cg04398451 chr17:18023971 MYO15A -0.32 -5.15 -0.42 1.01e-6 Total body bone mineral density; TGCT cis rs35306767 0.855 rs55708963 chr10:925712 C/A cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs6912958 0.781 rs6454631 chr6:88225863 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.51 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs752010 0.714 rs6664708 chr1:42083070 G/A cg06885757 chr1:42089581 HIVEP3 0.25 4.45 0.37 1.92e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs7659604 0.605 rs67772833 chr4:122723106 G/A cg19748678 chr4:122722346 EXOSC9 0.82 8.75 0.62 1.27e-14 Type 2 diabetes; TGCT cis rs7772486 0.817 rs2144477 chr6:146406248 C/T cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7819412 0.654 rs4840550 chr8:11029029 T/G cg21775007 chr8:11205619 TDH -0.56 -5.2 -0.42 8.06e-7 Triglycerides; TGCT cis rs7772486 0.875 rs2748498 chr6:146319166 C/G cg05347473 chr6:146136440 FBXO30 0.54 5.13 0.42 1.08e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7428 1.000 rs72840063 chr2:85550396 T/A cg24342717 chr2:85555507 TGOLN2 -0.41 -6.54 -0.51 1.43e-9 Ear protrusion; TGCT cis rs9549367 0.789 rs3850451 chr13:113905812 C/G cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs2346177 0.874 rs4953372 chr2:46651624 C/G cg26688816 chr2:46740690 ATP6V1E2 0.42 4.51 0.38 1.47e-5 HDL cholesterol; TGCT cis rs9910055 0.530 rs2269908 chr17:42294198 G/C cg19774624 chr17:42201019 HDAC5 -0.71 -7.51 -0.56 9.96e-12 Total body bone mineral density; TGCT cis rs1153858 1.000 rs12595087 chr15:45655232 A/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs4478858 0.611 rs7527645 chr1:31763787 T/C cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs10782582 0.609 rs5745325 chr1:76269460 G/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs9733 0.596 rs11204704 chr1:150671630 T/C cg09365446 chr1:150670422 GOLPH3L 0.3 4.49 0.37 1.63e-5 Tonsillectomy; TGCT cis rs612683 0.602 rs12565245 chr1:101019326 T/G cg06223162 chr1:101003688 GPR88 0.35 6.09 0.48 1.3e-8 Breast cancer; TGCT trans rs3107575 0.572 rs73169365 chr3:165319778 T/C cg04770195 chr16:53114571 CHD9 1.14 6.64 0.51 8.63e-10 Morning vs. evening chronotype; TGCT cis rs523522 0.962 rs2168319 chr12:120933217 C/T cg12219531 chr12:120966889 COQ5 0.83 7.28 0.55 3.4e-11 High light scatter reticulocyte count; TGCT cis rs35306767 0.623 rs36051896 chr10:1155747 T/C cg18964960 chr10:1102726 WDR37 0.65 4.45 0.37 1.93e-5 Eosinophil percentage of granulocytes; TGCT cis rs6448317 0.954 rs12186333 chr4:24919774 T/C cg21108841 chr4:24914750 CCDC149 -0.63 -4.81 -0.4 4.29e-6 Heschl's gyrus morphology; TGCT cis rs12477438 0.798 rs6736064 chr2:99658201 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg00684032 chr4:1343700 KIAA1530 0.25 5.09 0.42 1.28e-6 Obesity-related traits; TGCT cis rs1008375 0.932 rs4698630 chr4:17614692 C/G cg18681998 chr4:17616180 MED28 1.07 11.25 0.71 1.13e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs929354 0.742 rs6459734 chr7:156935454 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg11890956 chr21:40555474 PSMG1 1.11 12.17 0.74 6.69e-23 Cognitive function; TGCT cis rs1062177 0.502 rs10463321 chr5:151323905 T/G cg12924095 chr5:151150029 G3BP1 0.4 5.52 0.44 1.93e-7 Preschool internalizing problems; TGCT cis rs6939532 0.648 rs9379862 chr6:26370707 T/C cg05738196 chr6:26577821 NA -0.58 -5.0 -0.41 1.89e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7714584 1.000 rs2115069 chr5:150252365 G/A cg22134413 chr5:150180641 NA 0.88 6.69 0.51 6.89e-10 Crohn's disease; TGCT cis rs8103278 0.507 rs8112282 chr19:46265029 C/T cg11657440 chr19:46296263 DMWD 0.74 7.77 0.57 2.62e-12 Coronary artery disease; TGCT cis rs2243480 1.000 rs313807 chr7:65499481 C/T cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs694419 0.602 rs1606890 chr18:60181802 A/G cg13506219 chr18:60193840 ZCCHC2 -0.55 -4.93 -0.4 2.58e-6 Serum albumin level; TGCT cis rs7119038 0.818 rs11217032 chr11:118669605 T/A cg19308663 chr11:118741387 NA 0.31 6.43 0.5 2.56e-9 Sjögren's syndrome; TGCT cis rs2288073 0.965 rs72789923 chr2:24394504 A/C cg02683114 chr2:24398427 C2orf84 -0.25 -5.61 -0.45 1.26e-7 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs10197940 0.578 rs2432957 chr2:152287897 A/C cg19508488 chr2:152266495 RIF1 0.59 5.03 0.41 1.71e-6 Lung cancer; TGCT cis rs6752107 0.967 rs3792111 chr2:234179690 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.7 0.39 6.87e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4478858 0.698 rs7543348 chr1:31804805 A/C cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs11098499 0.954 rs67265404 chr4:120359270 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs2354432 0.556 rs72710311 chr1:146698256 A/G cg25205988 chr1:146714368 CHD1L -1.15 -4.8 -0.4 4.49e-6 Mitochondrial DNA levels; TGCT cis rs1784581 0.651 rs1784590 chr6:162389462 C/A cg17173639 chr6:162384350 PARK2 -0.47 -8.16 -0.59 3.15e-13 Itch intensity from mosquito bite; TGCT cis rs6750047 0.625 rs336037 chr2:38261124 T/C cg07380506 chr2:38303506 CYP1B1 -0.58 -5.2 -0.42 8.09e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs55883249 0.957 rs62119432 chr2:9753939 C/T cg23886495 chr2:9695866 ADAM17 0.79 4.66 0.39 8.09e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs926938 0.501 rs360686 chr1:115502524 C/T cg12756093 chr1:115239321 AMPD1 0.38 5.6 0.45 1.29e-7 Autism; TGCT cis rs28374715 0.787 rs11856169 chr15:41547938 C/T cg18705301 chr15:41695430 NDUFAF1 -0.83 -11.73 -0.73 7.87e-22 Ulcerative colitis; TGCT cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg08439880 chr3:133502540 NA -0.29 -5.42 -0.44 2.93e-7 Iron status biomarkers; TGCT cis rs79976124 0.797 rs79522358 chr6:66641140 C/G cg07460842 chr6:66804631 NA 0.57 5.22 0.42 7.44e-7 Type 2 diabetes; TGCT cis rs2050392 0.928 rs2250077 chr10:30702929 A/G cg18806716 chr10:30721971 MAP3K8 -0.46 -5.5 -0.44 2.04e-7 Inflammatory bowel disease; TGCT trans rs1005277 0.579 rs1548255 chr10:38417193 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.49 0.61 5.22e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2309752 1 rs2309752 chr2:100762169 T/A cg22139774 chr2:100720529 AFF3 -0.45 -8.1 -0.59 4.29e-13 Intelligence (multi-trait analysis); TGCT cis rs644799 0.562 rs1313288 chr11:95520695 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.57 6.21 0.49 7.25e-9 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7255045 0.742 rs4804738 chr19:12953183 T/G cg23899408 chr19:12877188 HOOK2 -0.61 -4.94 -0.41 2.48e-6 Mean corpuscular volume; TGCT cis rs6674176 0.660 rs2108202 chr1:44395786 A/G cg12908607 chr1:44402522 ARTN 0.74 9.15 0.63 1.43e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs875971 0.862 rs2420173 chr7:65645399 A/T cg11764359 chr7:65958608 NA -0.56 -5.04 -0.41 1.61e-6 Aortic root size; TGCT cis rs9393777 0.513 rs9393741 chr6:26654189 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs1055129 0.655 rs7216615 chr17:73833910 T/C cg10935138 chr17:73851978 WBP2 0.51 4.47 0.37 1.72e-5 White matter hyperintensity burden; TGCT cis rs4654899 0.965 rs17418249 chr1:21390582 C/T cg01072550 chr1:21505969 NA -0.49 -7.94 -0.58 1.05e-12 Superior frontal gyrus grey matter volume; TGCT cis rs1008375 0.966 rs1476836 chr4:17585014 G/C cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs208520 1.000 rs72882086 chr6:66976671 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.86 7.83 0.58 1.85e-12 Exhaled nitric oxide output; TGCT cis rs1801251 0.896 rs4973561 chr2:233687337 C/G cg25237894 chr2:233734115 C2orf82 -0.27 -5.0 -0.41 1.94e-6 Coronary artery disease; TGCT cis rs11792861 0.619 rs2289481 chr9:111712924 G/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.67 7.59 0.56 6.76e-12 Menarche (age at onset); TGCT cis rs1018836 0.786 rs10956736 chr8:91602067 C/T cg16814680 chr8:91681699 NA -0.71 -7.25 -0.55 3.89e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs8177253 0.965 rs1525889 chr3:133490033 A/C cg11941060 chr3:133502564 NA -0.29 -6.26 -0.49 5.88e-9 Iron status biomarkers; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg19626725 chr5:178986131 RUFY1 -0.55 -7.38 -0.55 1.96e-11 Lung cancer; TGCT cis rs899997 1.000 rs11633170 chr15:79004642 A/G cg04896959 chr15:78267971 NA -0.35 -4.81 -0.4 4.27e-6 Coronary artery disease or large artery stroke; TGCT cis rs8044995 0.563 rs2279540 chr16:68395061 T/C cg05110241 chr16:68378359 PRMT7 -0.36 -4.46 -0.37 1.84e-5 Schizophrenia; TGCT cis rs709400 0.894 rs56017123 chr14:104075277 G/A cg26031613 chr14:104095156 KLC1 1.15 16.05 0.82 4.72e-32 Body mass index; TGCT cis rs7666738 0.830 rs4472144 chr4:98956494 G/A cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1997103 1.000 rs4947503 chr7:55409427 G/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9660180 0.783 rs1107910 chr1:1692321 C/T cg20999797 chr1:1681921 NA 0.19 5.16 0.42 9.55e-7 Body mass index; TGCT cis rs11690462 0.963 rs7585892 chr2:26609469 G/A cg04726446 chr2:26624865 C2orf39 0.43 4.63 0.38 9.15e-6 Coronary artery disease; TGCT cis rs4733781 0.901 rs4733571 chr8:131290664 T/G cg16277922 chr8:131349729 ASAP1 0.38 4.91 0.4 2.82e-6 Tuberculosis; TGCT cis rs6752107 0.935 rs11688431 chr2:234147175 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.91 0.4 2.8e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2997447 0.802 rs61776621 chr1:26459058 C/G cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs11614913 0.551 rs1867297 chr12:54396971 A/G cg05643303 chr12:54402714 HOXC8 -0.71 -5.84 -0.46 4.28e-8 Waist circumference adjusted for body mass index; TGCT cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg27588902 chr6:42928151 GNMT -0.56 -6.91 -0.53 2.23e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7829975 0.536 rs2980439 chr8:8094870 G/A cg08975724 chr8:8085496 FLJ10661 0.63 5.92 0.47 2.94e-8 Mood instability; TGCT cis rs12477438 0.501 rs11692336 chr2:99740606 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs36051895 0.664 rs17425637 chr9:5110000 C/T cg02405213 chr9:5042618 JAK2 -0.7 -9.06 -0.63 2.38e-15 Pediatric autoimmune diseases; TGCT cis rs6540559 1.000 rs6540559 chr1:209982025 G/A cg22029157 chr1:209979665 IRF6 0.76 6.24 0.49 6.3e-9 Cleft lip with or without cleft palate; TGCT cis rs62064224 0.791 rs11654833 chr17:30667728 C/T cg09324608 chr17:30823087 MYO1D 0.24 4.59 0.38 1.09e-5 Schizophrenia; TGCT cis rs3087591 0.708 rs1129506 chr17:29646032 G/A cg24425628 chr17:29625626 OMG;NF1 0.35 5.01 0.41 1.82e-6 Hip circumference; TGCT cis rs617219 0.596 rs2131977 chr5:78613916 G/C cg05890484 chr5:78407552 BHMT -0.38 -5.16 -0.42 9.59e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs8077577 0.895 rs16960983 chr17:18104568 A/T cg09161412 chr17:18057145 MYO15A -0.61 -5.15 -0.42 9.98e-7 Obesity-related traits; TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg09333631 chr3:44802604 KIF15;KIAA1143 -0.4 -4.45 -0.37 1.86e-5 Depressive symptoms; TGCT cis rs916888 0.773 rs199534 chr17:44824213 T/G cg01570182 chr17:44337453 NA 1.07 9.81 0.66 3.57e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28595532 0.920 rs116331303 chr4:119754542 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT trans rs57221529 0.709 rs72707023 chr5:667620 G/A cg11887960 chr12:57824829 NA 1.14 9.47 0.65 2.39e-16 Lung disease severity in cystic fibrosis; TGCT cis rs3617 0.573 rs9860296 chr3:52913781 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.56 -0.38 1.2e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs875971 0.862 rs709609 chr7:65560561 A/G cg11764359 chr7:65958608 NA -0.56 -4.82 -0.4 4.1e-6 Aortic root size; TGCT cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg22166914 chr1:53195759 ZYG11B -0.39 -6.57 -0.51 1.22e-9 Monocyte count; TGCT cis rs2718812 0.766 rs1822744 chr3:133366227 A/G cg08048268 chr3:133502702 NA -0.38 -4.73 -0.39 6.03e-6 Iron status biomarkers; TGCT cis rs2637266 0.703 rs846624 chr10:78541381 G/A cg18941641 chr10:78392320 NA 0.39 4.63 0.38 9.26e-6 Pulmonary function; TGCT cis rs7086627 0.515 rs4934189 chr10:82214792 C/T cg01528321 chr10:82214614 TSPAN14 0.65 6.22 0.49 7.09e-9 Post bronchodilator FEV1; TGCT cis rs2301573 1.000 rs12635414 chr3:129312981 G/A cg12216435 chr3:128995479 COPG 0.51 4.52 0.38 1.42e-5 Hip circumference; TGCT cis rs6089829 1.000 rs62207535 chr20:61669187 A/G cg08564027 chr20:61660810 NA 0.37 6.64 0.51 8.71e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs6860806 0.507 rs274570 chr5:131713226 C/T cg24060327 chr5:131705240 SLC22A5 0.71 7.64 0.57 5.04e-12 Breast cancer; TGCT cis rs6860806 0.531 rs272888 chr5:131665423 T/C cg24060327 chr5:131705240 SLC22A5 -0.73 -7.83 -0.58 1.83e-12 Breast cancer; TGCT cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg14983838 chr19:29218262 NA 0.86 7.07 0.54 9.71e-11 Methadone dose in opioid dependence; TGCT cis rs28386778 0.830 rs2854210 chr17:61946338 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.36 0.55 2.26e-11 Prudent dietary pattern; TGCT cis rs8072100 0.840 rs56952963 chr17:45493826 T/C cg08085267 chr17:45401833 C17orf57 -0.51 -5.71 -0.46 8.04e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2180341 1.000 rs7776136 chr6:127638348 A/T cg27446573 chr6:127587934 RNF146 1.07 9.67 0.66 8.11e-17 Breast cancer; TGCT cis rs7216064 0.684 rs62084675 chr17:66027025 A/G cg12091567 chr17:66097778 LOC651250 1.07 8.8 0.62 9.68e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2354432 0.556 rs12568866 chr1:146718430 A/C cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs3784262 0.631 rs6493980 chr15:58352290 A/G cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.24 -0.49 6.32e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs13223928 0.565 rs10240820 chr7:3154415 T/C cg19214707 chr7:3157722 NA -0.49 -6.96 -0.53 1.72e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs12142240 0.698 rs17413701 chr1:46818452 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6089829 0.962 rs6089824 chr20:61659207 A/G cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs854765 0.547 rs2955355 chr17:17948475 G/A cg09796270 chr17:17721594 SREBF1 -0.26 -5.16 -0.42 9.37e-7 Total body bone mineral density; TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg06493612 chr6:15502050 JARID2 0.63 5.44 0.44 2.77e-7 Gambling; TGCT cis rs1034435 0.755 rs5767173 chr22:48892473 T/C cg05992904 chr22:48892994 FAM19A5 -0.34 -4.65 -0.39 8.44e-6 Late-onset Alzheimer's disease; TGCT cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg16325326 chr1:53192061 ZYG11B -0.84 -11.96 -0.73 2.15e-22 Monocyte count; TGCT trans rs12103 0.749 rs2649599 chr1:1305493 A/G cg16196077 chr10:64028521 RTKN2 -0.92 -10.18 -0.67 4.67e-18 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; TGCT cis rs7267979 0.844 rs2257649 chr20:25263457 T/G cg16686733 chr20:25566563 NINL 0.52 4.93 0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9910055 0.531 rs6503490 chr17:42246656 A/G cg13607699 chr17:42295918 UBTF 0.6 5.51 0.44 1.96e-7 Total body bone mineral density; TGCT cis rs244731 0.959 rs4976677 chr5:176629546 G/A cg16006841 chr5:176797999 RGS14 -0.53 -6.95 -0.53 1.88e-10 Urate levels in lean individuals; TGCT cis rs7552404 0.824 rs1251077 chr1:76189745 C/G cg03433033 chr1:76189801 ACADM -0.9 -14.45 -0.79 2.31e-28 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4654899 0.895 rs10916865 chr1:21136610 C/T cg01072550 chr1:21505969 NA 0.51 8.07 0.59 5.11e-13 Superior frontal gyrus grey matter volume; TGCT cis rs447735 0.565 rs10852626 chr16:89914633 T/G cg04287289 chr16:89883240 FANCA 0.69 6.59 0.51 1.15e-9 Hemoglobin concentration; TGCT cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs4984778 0.750 rs7198064 chr16:1272472 C/T cg07748719 chr16:1272498 TPSG1 0.51 6.51 0.5 1.7e-9 Blood protein levels; TGCT cis rs736408 0.812 rs2071507 chr3:52826707 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.5 4.62 0.38 9.39e-6 Bipolar disorder; TGCT cis rs6500602 0.564 rs3747584 chr16:4516092 A/G cg08645402 chr16:4508243 NA 0.21 5.02 0.41 1.76e-6 Schizophrenia; TGCT cis rs17401966 0.858 rs61778404 chr1:10432879 A/G cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs904251 0.523 rs2776920 chr6:37480605 G/A cg08126542 chr6:37504118 NA -0.46 -6.64 -0.51 8.96e-10 Cognitive performance; TGCT cis rs9383153 0.793 rs2016498 chr6:16344914 C/T cg14009473 chr6:15502099 JARID2 0.65 5.76 0.46 6.2e-8 Gambling; TGCT cis rs8017423 0.935 rs9944124 chr14:90791501 T/C cg04374321 chr14:90722782 PSMC1 0.74 7.09 0.54 8.75e-11 Mortality in heart failure; TGCT cis rs2070488 1.000 rs7373816 chr3:38490443 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs5750830 0.649 rs5750815 chr22:39798449 T/C cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg04317338 chr11:64019027 PLCB3 0.78 6.42 0.5 2.63e-9 Mean platelet volume; TGCT cis rs10946940 1.000 rs10946940 chr6:27560587 A/G cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.73 -0.39 6.01e-6 Systemic lupus erythematosus; TGCT cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg11644478 chr21:40555479 PSMG1 -0.65 -5.89 -0.47 3.34e-8 Cognitive function; TGCT cis rs1005277 0.579 rs1780121 chr10:38529437 C/A cg25427524 chr10:38739819 LOC399744 -0.4 -8.36 -0.6 1.05e-13 Extrinsic epigenetic age acceleration; TGCT cis rs61935443 1.000 rs61935443 chr12:95249764 G/C cg21533806 chr12:95267307 NA 0.52 4.55 0.38 1.26e-5 Schizophrenia; TGCT cis rs7811142 1.000 rs11773661 chr7:100073069 G/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs7147624 1.000 rs2411349 chr14:66214426 T/C cg03016385 chr14:66212404 NA -0.5 -7.11 -0.54 8.15e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs74181299 0.819 rs2252867 chr2:65296280 T/C cg05010058 chr2:65284262 CEP68 0.43 4.71 0.39 6.58e-6 Pulse pressure; TGCT cis rs7246657 0.941 rs12982333 chr19:37794724 A/G cg18154014 chr19:37997991 ZNF793 0.81 5.56 0.45 1.61e-7 Coronary artery calcification; TGCT cis rs11971779 0.646 rs58682779 chr7:139084712 C/T cg07862535 chr7:139043722 LUC7L2 0.79 5.8 0.46 5.13e-8 Diisocyanate-induced asthma; TGCT cis rs7618915 0.501 rs11714030 chr3:52765882 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.09 -0.67 7.59e-18 Bipolar disorder; TGCT cis rs524281 1.000 rs527897 chr11:65900777 C/T cg00563793 chr11:65837595 PACS1 0.52 4.67 0.39 7.69e-6 Electroencephalogram traits; TGCT cis rs78487399 0.808 rs7564886 chr2:43733028 G/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.5 0.37 1.57e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12286929 1.000 rs12286929 chr11:115022404 A/G cg04017736 chr11:115827165 NA -0.19 -4.44 -0.37 1.98e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs8077889 0.871 rs8081101 chr17:41904332 C/T cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs4253772 0.637 rs9627350 chr22:46663017 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.57 4.48 0.37 1.69e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs459571 0.959 rs2810491 chr9:136923331 C/T cg13789015 chr9:136890014 NCRNA00094 -0.39 -7.04 -0.53 1.16e-10 Platelet distribution width; TGCT cis rs911186 0.812 rs6932590 chr6:27248931 T/C cg11262757 chr6:27280423 POM121L2 0.6 4.77 0.39 5.04e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.753 rs2903143 chr4:99040480 C/T cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs6728302 0.557 rs73002000 chr2:233254052 C/T cg06555452 chr2:233241558 NA 0.36 5.06 0.41 1.49e-6 Height; TGCT cis rs533581 0.816 rs533406 chr16:88974860 A/G cg16701003 chr16:89028210 CBFA2T3 0.34 4.76 0.39 5.2e-6 Social autistic-like traits; TGCT cis rs1497406 0.744 rs10907282 chr1:16510139 A/G cg20430773 chr1:16534157 ARHGEF19 0.55 6.11 0.48 1.18e-8 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs35306767 0.761 rs11253557 chr10:1043667 C/T cg18964960 chr10:1102726 WDR37 0.79 5.55 0.45 1.67e-7 Eosinophil percentage of granulocytes; TGCT cis rs1215050 0.791 rs649866 chr4:98738826 T/C cg05340658 chr4:99064831 C4orf37 0.44 5.62 0.45 1.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7833790 0.724 rs6473309 chr8:82707880 A/G cg27398817 chr8:82754497 SNX16 -0.68 -5.34 -0.43 4.28e-7 Diastolic blood pressure; TGCT cis rs727505 1.000 rs56387611 chr7:124479180 G/A cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs7552167 0.925 rs3932666 chr1:24511566 G/A cg01960748 chr1:24522592 NA -0.49 -5.49 -0.44 2.13e-7 Psoriasis vulgaris; TGCT cis rs2639990 1.000 rs632157 chr18:72911548 G/A cg18449964 chr18:72917101 ZADH2 0.92 6.07 0.48 1.46e-8 Vascular endothelial growth factor levels; TGCT cis rs12477438 0.798 rs6761570 chr2:99577276 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg17554472 chr22:41940697 POLR3H 0.47 5.04 0.41 1.63e-6 Vitiligo; TGCT cis rs1008375 0.606 rs6828925 chr4:17561139 C/T cg18681998 chr4:17616180 MED28 0.75 7.46 0.56 1.34e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs929354 0.742 rs1182396 chr7:157031831 A/C cg05182265 chr7:156933206 UBE3C 0.39 8.85 0.62 7.32e-15 Body mass index; TGCT cis rs7772486 0.875 rs2748485 chr6:146332421 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.55 0.65 1.57e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs12765878 0.967 rs10883941 chr10:105650782 C/T cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs17122693 0.748 rs61607560 chr14:51143649 C/T cg04730355 chr14:51134070 SAV1 1.33 12.04 0.73 1.37e-22 Cognitive performance; TGCT cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg18735214 chr6:43276756 CRIP3 -0.53 -4.56 -0.38 1.21e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs3774830 0.967 rs1004375 chr4:5438478 G/A cg26943120 chr4:5472116 STK32B 0.21 4.63 0.38 8.96e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs13102973 0.720 rs13122447 chr4:135887524 C/T cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg17971929 chr21:40555470 PSMG1 0.97 9.4 0.65 3.57e-16 Cognitive function; TGCT cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg03609598 chr5:56110824 MAP3K1 -0.58 -4.66 -0.39 7.94e-6 Initial pursuit acceleration; TGCT cis rs7829975 0.659 rs4382480 chr8:8721473 C/T cg15556689 chr8:8085844 FLJ10661 0.73 7.28 0.55 3.34e-11 Mood instability; TGCT cis rs314370 1.000 rs12705089 chr7:100465355 C/T cg10426581 chr7:100472382 SRRT 0.98 10.52 0.69 7e-19 Resting heart rate; TGCT cis rs4851254 0.618 rs7572939 chr2:100654914 A/G cg22139774 chr2:100720529 AFF3 -0.46 -4.97 -0.41 2.16e-6 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.772 rs4845694 chr1:154911651 C/G cg16680214 chr1:154839983 KCNN3 -0.35 -7.11 -0.54 8.04e-11 Prostate cancer; TGCT cis rs6938 0.596 rs11072511 chr15:75159433 A/G cg10253484 chr15:75165896 SCAMP2 -0.52 -4.79 -0.39 4.77e-6 Breast cancer; TGCT trans rs7613875 0.663 rs6762477 chr3:50093209 G/A cg21659725 chr3:3221576 CRBN -0.67 -7.53 -0.56 9.05e-12 Body mass index; TGCT cis rs6582630 0.519 rs11495373 chr12:38275470 T/C cg13010199 chr12:38710504 ALG10B 0.6 4.65 0.39 8.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs3820068 0.705 rs72645808 chr1:15870118 G/C cg05660106 chr1:15850417 CASP9 1.13 13.14 0.76 3.06e-25 Systolic blood pressure; TGCT cis rs2742417 1.000 rs2742421 chr3:45732515 G/T cg04837898 chr3:45731254 SACM1L 0.55 5.68 0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs8044995 0.563 rs56899435 chr16:68395675 G/A cg05110241 chr16:68378359 PRMT7 -0.36 -4.46 -0.37 1.84e-5 Schizophrenia; TGCT cis rs4891159 0.790 rs4891018 chr18:74127082 A/T cg24786174 chr18:74118243 ZNF516 -0.59 -8.98 -0.63 3.73e-15 Longevity; TGCT trans rs6089829 0.926 rs1060491 chr20:61665817 C/A cg13615516 chr5:77269221 NA -0.68 -8.33 -0.6 1.3e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs12477438 0.798 rs4850891 chr2:99574642 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.7 -6.22 -0.49 7.15e-9 Chronic sinus infection; TGCT trans rs561341 0.740 rs11080174 chr17:30208521 C/A cg20587970 chr11:113659929 NA 0.65 8.98 0.63 3.67e-15 Hip circumference adjusted for BMI; TGCT cis rs2836950 0.585 rs1029004 chr21:40615343 A/G cg11644478 chr21:40555479 PSMG1 -0.52 -4.84 -0.4 3.78e-6 Menarche (age at onset); TGCT cis rs74233809 1.000 rs10458729 chr10:104841479 C/T cg05855489 chr10:104503620 C10orf26 0.79 4.56 0.38 1.19e-5 Birth weight; TGCT cis rs11651000 0.817 rs7502875 chr17:45823227 A/C cg06532163 chr17:45867833 NA 0.35 4.99 0.41 2.01e-6 IgG glycosylation; TGCT cis rs11754661 1.000 rs73011397 chr6:151205678 A/G cg11579907 chr6:151412213 MTHFD1L 0.54 4.9 0.4 2.99e-6 Alzheimer's disease (late onset); TGCT cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg10295955 chr4:187884368 NA 0.94 14.0 0.78 2.69e-27 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 0.900 rs6851783 chr4:17578469 A/G cg10189774 chr4:17578691 LAP3 0.61 5.15 0.42 9.88e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1903068 0.927 rs12331507 chr4:56011889 A/G cg01777861 chr4:56023843 NA -0.49 -5.68 -0.45 9.21e-8 Endometriosis; TGCT cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg06238570 chr21:40685208 BRWD1 0.72 6.58 0.51 1.16e-9 Cognitive function; TGCT cis rs801193 1.000 rs10234018 chr7:66146284 A/T cg00343986 chr7:65444356 GUSB -0.22 -4.88 -0.4 3.13e-6 Aortic root size; TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg15687855 chr3:44754131 ZNF502 -0.45 -5.4 -0.44 3.24e-7 Depressive symptoms; TGCT cis rs3820928 0.874 rs1917127 chr2:227895125 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs3008870 0.916 rs2025608 chr1:67422550 C/T cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs1670533 1.000 rs62879260 chr4:1050850 T/C cg20887711 chr4:1340912 KIAA1530 0.7 5.66 0.45 9.77e-8 Recombination rate (females); TGCT cis rs11754661 1.000 rs73011386 chr6:151196854 C/T cg01354656 chr6:151411710 MTHFD1L 0.48 4.49 0.37 1.61e-5 Alzheimer's disease (late onset); TGCT cis rs2456568 0.709 rs1354765 chr11:93637776 G/T cg17595323 chr11:93583763 C11orf90 0.47 6.28 0.49 5.27e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4455778 0.538 rs4288325 chr7:49130239 G/A cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.02e-9 Lung cancer in never smokers; TGCT cis rs7666738 0.830 rs10010223 chr4:99021758 G/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2469997 1.000 rs2447171 chr8:120360953 C/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs7412746 0.658 rs11581757 chr1:150892244 A/G cg09365446 chr1:150670422 GOLPH3L 0.33 4.73 0.39 6.05e-6 Melanoma; TGCT cis rs79349575 0.749 rs46521 chr17:46988529 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs11190604 1.000 rs7079756 chr10:102302105 G/A cg23241863 chr10:102295624 HIF1AN 0.72 5.33 0.43 4.52e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7586879 0.616 rs6722587 chr2:25132192 C/A cg01884057 chr2:25150051 NA 0.36 7.1 0.54 8.43e-11 Body mass index; TGCT cis rs8017423 0.967 rs55894943 chr14:90714799 A/G cg04374321 chr14:90722782 PSMC1 0.74 7.5 0.56 1.09e-11 Mortality in heart failure; TGCT cis rs7809950 0.954 rs2189839 chr7:107230026 A/G cg23024343 chr7:107201750 COG5 0.35 5.41 0.44 3.18e-7 Coronary artery disease; TGCT cis rs17152411 0.895 rs7084646 chr10:126585738 T/C cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs561341 0.740 rs11080174 chr17:30208521 C/A cg13647721 chr17:30228624 UTP6 -0.61 -4.81 -0.4 4.26e-6 Hip circumference adjusted for BMI; TGCT cis rs9926296 0.605 rs8047486 chr16:89854025 A/T cg04287289 chr16:89883240 FANCA 0.93 11.83 0.73 4.42e-22 Vitiligo; TGCT cis rs2836974 0.897 rs13049280 chr21:40594656 C/G cg17971929 chr21:40555470 PSMG1 0.94 9.11 0.63 1.78e-15 Cognitive function; TGCT cis rs6089829 0.926 rs6011552 chr20:61667894 T/C cg08564027 chr20:61660810 NA 0.36 6.5 0.5 1.77e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs739401 0.611 rs402276 chr11:3051404 C/G cg05729581 chr11:3078854 CARS -0.55 -5.15 -0.42 9.85e-7 Longevity; TGCT cis rs9929218 0.529 rs8059194 chr16:68749663 C/T cg01251360 chr16:68772225 CDH1 -0.26 -4.9 -0.4 2.88e-6 Colorectal cancer; TGCT cis rs7666738 0.791 rs1527516 chr4:98967937 A/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs921968 0.541 rs55996799 chr2:219558193 C/G cg02176678 chr2:219576539 TTLL4 -0.5 -6.98 -0.53 1.56e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs9916302 0.752 rs6503513 chr17:37561613 A/G cg07936489 chr17:37558343 FBXL20 0.91 7.57 0.56 7.21e-12 Glomerular filtration rate (creatinine); TGCT cis rs11096990 0.634 rs10019594 chr4:39288747 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.19 -0.54 5.48e-11 Prostate cancer; TGCT cis rs270601 0.683 rs81598 chr5:131587960 C/G cg12564285 chr5:131593104 PDLIM4 0.4 4.84 0.4 3.79e-6 Acylcarnitine levels; TGCT cis rs9660992 0.639 rs1151786 chr1:205227760 G/C cg00857998 chr1:205179979 DSTYK 0.52 4.65 0.39 8.41e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs1577917 1.000 rs12205336 chr6:86722367 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs9926296 0.624 rs1110331 chr16:89774396 A/G cg09028487 chr16:89985162 MC1R -0.52 -4.49 -0.37 1.58e-5 Vitiligo; TGCT cis rs9611565 0.649 rs4822050 chr22:42177453 C/G cg17554472 chr22:41940697 POLR3H -0.44 -4.68 -0.39 7.53e-6 Vitiligo; TGCT cis rs2180341 1.000 rs9398837 chr6:127635217 G/A cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs28595532 0.920 rs116105567 chr4:119746204 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs1967977 chr4:98966141 A/G cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.84e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9443189 0.762 rs2748944 chr6:76436106 A/G cg01950844 chr6:76311363 SENP6 0.62 4.48 0.37 1.69e-5 Prostate cancer; TGCT cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg03806693 chr22:41940476 POLR3H -1.13 -12.67 -0.75 4.12e-24 Vitiligo; TGCT cis rs3960554 0.569 rs10464565 chr7:75869526 T/G cg19105122 chr7:75896889 SRRM3 0.58 4.98 0.41 2.1e-6 Eotaxin levels; TGCT cis rs10504229 0.683 rs7820559 chr8:58142662 C/T cg02725872 chr8:58115012 NA -0.36 -4.83 -0.4 3.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.798 rs972768 chr2:99682397 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs4285028 0.656 rs2141487 chr3:121482765 A/G cg01951420 chr3:121553821 IQCB1;EAF2 1.03 8.75 0.62 1.26e-14 Multiple sclerosis; TGCT cis rs1865760 1.000 rs2071297 chr6:25924513 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.65 -6.11 -0.48 1.18e-8 Height; TGCT cis rs7267979 0.816 rs376742 chr20:25487417 A/C cg03522245 chr20:25566470 NINL 0.56 5.74 0.46 6.76e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1692580 0.807 rs12040414 chr1:2192948 T/C cg21194808 chr1:2205498 SKI 0.29 5.78 0.46 5.71e-8 Coronary artery disease; TGCT cis rs9818758 0.607 rs56306491 chr3:49314960 G/A cg00383909 chr3:49044727 WDR6 1.31 6.76 0.52 4.72e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs12188164 0.965 rs11744539 chr5:451425 C/T cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs2296887 0.591 rs7897947 chr10:104157711 T/G cg26089160 chr10:104170217 PSD -0.67 -6.37 -0.5 3.43e-9 Parkinson's disease; TGCT cis rs910316 0.737 rs175071 chr14:75498177 A/G cg11812906 chr14:75593930 NEK9 -0.58 -5.44 -0.44 2.7e-7 Height; TGCT trans rs7726839 0.794 rs10053310 chr5:595661 C/G cg25482853 chr8:67687455 SGK3 0.97 7.64 0.57 5.1e-12 Obesity-related traits; TGCT cis rs11122272 0.735 rs2009873 chr1:231499236 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.63 -0.51 9.1e-10 Hemoglobin concentration; TGCT cis rs12541335 0.639 rs11779277 chr8:22200683 C/T cg07298985 chr8:22133076 PIWIL2 0.34 5.41 0.44 3.07e-7 Hypertriglyceridemia; TGCT cis rs9368481 0.729 rs9379948 chr6:26944783 T/G cg07220782 chr6:26987966 LOC100270746;C6orf41 0.46 5.21 0.42 7.7300000000000005e-07 Autism spectrum disorder or schizophrenia; TGCT cis rs7617773 0.780 rs3197223 chr3:48335857 C/T cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs2841277 0.708 rs10083496 chr14:105402786 G/A cg21017887 chr14:105400489 NA 0.38 5.42 0.44 3.03e-7 Rheumatoid arthritis; TGCT cis rs5750830 0.594 rs6001587 chr22:39819008 T/C cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs4822044 0.680 rs8138780 chr22:42097462 A/T cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Cannabis dependence symptom count; TGCT cis rs28374715 0.662 rs691907 chr15:41474657 C/G cg18705301 chr15:41695430 NDUFAF1 0.74 11.02 0.7 4.25e-20 Ulcerative colitis; TGCT cis rs8064299 0.655 rs734232 chr17:72765731 C/T cg25054828 chr17:72772726 NAT9;TMEM104 0.58 5.43 0.44 2.87e-7 Monocyte count; TGCT cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg06640241 chr16:89574553 SPG7 0.81 9.38 0.64 4.02e-16 Multiple myeloma (IgH translocation); TGCT cis rs10791097 0.694 rs10160281 chr11:130742788 T/C cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs319204 0.843 rs319170 chr5:146290208 T/C cg25021259 chr5:146258546 PPP2R2B 0.35 4.49 0.37 1.64e-5 Schizophrenia; TGCT cis rs2180341 0.814 rs6919277 chr6:127738050 T/C cg24812749 chr6:127587940 RNF146 0.75 6.07 0.48 1.41e-8 Breast cancer; TGCT cis rs1372520 0.627 rs2737025 chr4:90719192 A/G cg14346243 chr4:90757452 SNCA -0.68 -5.64 -0.45 1.12e-7 Neuroticism; TGCT cis rs7216064 1.000 rs2128792 chr17:65857177 C/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs908922 0.605 rs3753448 chr1:152486407 A/C cg20991723 chr1:152506922 NA 0.47 6.5 0.5 1.73e-9 Hair morphology; TGCT cis rs11190604 0.806 rs76835764 chr10:102193612 C/T cg16005271 chr10:102321736 NA 0.46 4.69 0.39 6.99e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg24829409 chr8:58192753 C8orf71 0.61 5.15 0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs7424096 0.555 rs75219072 chr2:37225706 C/T cg14987922 chr2:37194071 STRN 0.52 4.53 0.38 1.37e-5 High light scatter reticulocyte percentage of red cells; TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs1536827 0.688 rs2031922 chr10:135340093 T/C cg12448312 chr10:135032219 KNDC1 -0.41 -4.65 -0.39 8.42e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12950390 0.853 rs56387656 chr17:45860189 C/G cg06532163 chr17:45867833 NA 0.37 5.96 0.47 2.45e-8 IgG glycosylation; TGCT trans rs6089829 0.962 rs6089824 chr20:61659207 A/G cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs11252926 0.537 rs4881274 chr10:459940 G/A cg20256804 chr10:444983 DIP2C -0.21 -4.47 -0.37 1.74e-5 Psychosis in Alzheimer's disease; TGCT cis rs877426 0.515 rs57506460 chr13:114767789 G/A cg16820615 chr13:114884918 RASA3 0.28 4.97 0.41 2.17e-6 Facial morphology (factor 14, intercanthal width); TGCT cis rs4891159 0.790 rs59762437 chr18:74153146 G/A cg24786174 chr18:74118243 ZNF516 -0.54 -7.08 -0.54 9.37e-11 Longevity; TGCT cis rs546131 0.928 rs499183 chr11:34836678 A/G cg06937548 chr11:34938143 PDHX;APIP 0.62 5.6 0.45 1.31e-7 Lung disease severity in cystic fibrosis; TGCT cis rs12048904 0.930 rs11166529 chr1:101333733 C/T cg15686842 chr1:101360669 SLC30A7;EXTL2 0.49 4.46 0.37 1.8e-5 Multiple sclerosis; TGCT cis rs12216125 0.554 rs6942196 chr6:26072804 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.79 7.55 0.56 8.02e-12 Iron status biomarkers; TGCT cis rs595982 0.702 rs623520 chr19:49369943 A/G cg15549821 chr19:49342101 PLEKHA4 -0.38 -5.16 -0.42 9.34e-7 Red cell distribution width; TGCT cis rs6714710 0.580 rs57804205 chr2:98454472 G/A cg26665480 chr2:98280029 ACTR1B 0.66 6.26 0.49 5.74e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs4689388 0.926 rs12508672 chr4:6287965 G/A cg14416269 chr4:6271139 WFS1 0.37 4.87 0.4 3.39e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs7523050 0.643 rs34367763 chr1:109400805 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs6089584 0.861 rs2180302 chr20:60576369 A/G cg16423285 chr20:60520624 NA -0.63 -6.7 -0.52 6.45e-10 Body mass index; TGCT trans rs7618501 0.521 rs3733134 chr3:49939503 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.83 8.73 0.62 1.45e-14 Intelligence (multi-trait analysis); TGCT cis rs986417 1.000 rs10142455 chr14:60980963 G/A cg27398547 chr14:60952738 C14orf39 1.48 11.21 0.71 1.46e-20 Gut microbiota (bacterial taxa); TGCT cis rs3847687 1.000 rs11061292 chr12:131518981 T/A cg13586425 chr12:131519906 GPR133 -0.34 -5.33 -0.43 4.47e-7 Longevity; TGCT cis rs78366141 0.536 rs78517451 chr4:89650437 C/A cg01026744 chr4:89619053 NAP1L5;HERC3 1.15 5.14 0.42 1.03e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs10992471 0.598 rs3174352 chr9:95219248 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.64 6.22 0.49 7.07e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7208859 0.623 rs383436 chr17:28959179 A/G cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7552404 0.727 rs2172508 chr1:76320215 A/G cg10523679 chr1:76189770 ACADM 0.68 6.25 0.49 6.11e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2692947 0.794 rs2692893 chr2:96756547 C/T cg23100626 chr2:96804247 ASTL 0.41 4.84 0.4 3.74e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs950169 0.580 rs4603535 chr15:85173872 C/T cg17173187 chr15:85201210 NMB 0.62 7.09 0.54 8.99e-11 Schizophrenia; TGCT cis rs7178572 0.568 rs11858641 chr15:77585820 C/T cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs3888647 0.622 rs4758618 chr11:2995186 A/T cg05729581 chr11:3078854 CARS -0.54 -4.82 -0.4 4.19e-6 Type 2 diabetes; TGCT cis rs7584330 0.695 rs6709497 chr2:238368925 C/T cg08992911 chr2:238395768 MLPH 0.56 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs477692 0.625 rs4751104 chr10:131405358 G/A cg24747557 chr10:131355152 MGMT 0.3 4.59 0.38 1.05e-5 Response to temozolomide; TGCT cis rs60871478 0.636 rs6976929 chr7:901382 C/T cg00475322 chr7:917719 C7orf20 0.5 4.82 0.4 4.14e-6 Cerebrospinal P-tau181p levels; TGCT trans rs916888 0.773 rs199534 chr17:44824213 T/G cg22968622 chr17:43663579 NA 1.3 11.87 0.73 3.46e-22 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4747241 1.000 rs10740398 chr10:74046191 C/G cg09661010 chr10:73848153 SPOCK2 0.4 4.46 0.37 1.8e-5 Heschl's gyrus morphology; TGCT cis rs11677416 1.000 rs34015482 chr2:113525745 A/G cg27083787 chr2:113543245 IL1A 0.17 4.46 0.37 1.83e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs4499344 0.633 rs166311 chr19:33161246 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.87 9.38 0.64 4.1e-16 Mean platelet volume; TGCT cis rs9318086 0.673 rs7981928 chr13:24435180 T/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.8 8.48 0.61 5.49e-14 Myopia (pathological); TGCT cis rs116095464 0.558 rs10052012 chr5:231908 T/C cg22857025 chr5:266934 NA -0.33 -6.57 -0.51 1.22e-9 Breast cancer; TGCT cis rs17401966 0.894 rs11587309 chr1:10446596 G/T cg19773385 chr1:10388646 KIF1B -0.23 -5.3 -0.43 5.14e-7 Hepatocellular carcinoma; TGCT cis rs10193935 0.901 rs10196091 chr2:42541591 T/C cg27598129 chr2:42591480 NA -0.4 -5.55 -0.45 1.68e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs62321570 chr4:98984276 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.931 rs9311430 chr3:48845251 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs17152411 0.793 rs7085829 chr10:126587142 A/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs1062177 1.000 rs2915882 chr5:151145436 T/C cg12924095 chr5:151150029 G3BP1 0.35 5.07 0.41 1.41e-6 Preschool internalizing problems; TGCT cis rs6952808 0.656 rs12699646 chr7:2093162 T/G cg22963979 chr7:1858916 MAD1L1 0.39 5.96 0.47 2.43e-8 Bipolar disorder and schizophrenia; TGCT cis rs4654899 0.897 rs10916859 chr1:21087956 A/G cg01072550 chr1:21505969 NA -0.5 -8.03 -0.59 6.32e-13 Superior frontal gyrus grey matter volume; TGCT cis rs9372498 0.536 rs77435770 chr6:118819467 G/A cg21191810 chr6:118973309 C6orf204 -0.35 -4.72 -0.39 6.2e-6 Diastolic blood pressure; TGCT cis rs1691799 0.899 rs1168295 chr12:66734151 G/C cg16791601 chr12:66731901 HELB -0.29 -6.31 -0.49 4.41e-9 White blood cell count (basophil); TGCT trans rs1814175 0.817 rs1818890 chr11:49856882 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs798554 0.679 rs2527681 chr7:2892384 A/T cg04166393 chr7:2884313 GNA12 0.56 4.61 0.38 9.9e-6 Height; TGCT cis rs853679 0.546 rs200977 chr6:27854301 T/C cg08798685 chr6:27730294 NA -0.36 -5.01 -0.41 1.86e-6 Depression; TGCT cis rs7085104 0.660 rs3781286 chr10:104595719 C/T cg04362960 chr10:104952993 NT5C2 0.55 4.92 0.4 2.7e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs4499344 0.657 rs4805769 chr19:33049697 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.72 -6.16 -0.48 9.45e-9 Mean platelet volume; TGCT cis rs916888 0.531 rs183211 chr17:44788310 G/A cg17911788 chr17:44343683 NA -0.48 -5.65 -0.45 1.05e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7119 0.717 rs12909645 chr15:77816819 A/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs7772486 0.875 rs2492855 chr6:146296926 A/G cg23711669 chr6:146136114 FBXO30 0.85 9.21 0.64 1.03e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs9677476 0.516 rs11893395 chr2:232022981 G/A cg27665808 chr2:232055229 NA 0.36 4.51 0.38 1.48e-5 Food antigen IgG levels; TGCT cis rs12188164 0.686 rs72711365 chr5:416672 G/A cg26850624 chr5:429559 AHRR -0.22 -5.08 -0.41 1.36e-6 Cystic fibrosis severity; TGCT cis rs1552244 1.000 rs2272123 chr3:10140115 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs9660180 0.967 rs9660106 chr1:1797947 A/G cg17747265 chr1:1875780 NA -0.43 -8.09 -0.59 4.69e-13 Body mass index; TGCT cis rs2242116 0.796 rs4683296 chr3:46973820 G/C cg23352942 chr3:46931381 PTH1R 0.31 4.44 0.37 1.94e-5 Birth weight; TGCT cis rs6121246 0.909 rs1994250 chr20:30287494 A/G cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs62064224 0.512 rs9912766 chr17:30712780 A/G cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.77e-6 Schizophrenia; TGCT cis rs853679 0.546 rs200995 chr6:27813694 C/T cg08798685 chr6:27730294 NA 0.34 4.77 0.39 5.13e-6 Depression; TGCT cis rs826838 0.616 rs4619214 chr12:38614704 C/A cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Heart rate; TGCT cis rs6951245 0.529 rs10262070 chr7:1141738 C/T cg09177884 chr7:1199841 ZFAND2A -0.64 -5.14 -0.42 1.04e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs769267 1.000 rs3764567 chr19:19440066 C/T cg03709012 chr19:19516395 GATAD2A -0.65 -5.47 -0.44 2.34e-7 Tonsillectomy; TGCT cis rs7818688 0.697 rs74553842 chr8:95984392 C/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs986417 1.000 rs8015462 chr14:61046687 G/A cg18240143 chr14:60952599 C14orf39 0.88 4.78 0.39 4.84e-6 Gut microbiota (bacterial taxa); TGCT cis rs17152411 1.000 rs17152381 chr10:126592903 T/G cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg01585852 chr22:24235823 MIF -0.22 -4.79 -0.4 4.65e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7829975 0.560 rs4841013 chr8:8552013 A/G cg17143192 chr8:8559678 CLDN23 -0.49 -4.94 -0.41 2.44e-6 Mood instability; TGCT cis rs62103177 0.759 rs7227794 chr18:77610925 C/T cg12964065 chr18:77638022 KCNG2 0.41 5.48 0.44 2.31e-7 Opioid sensitivity; TGCT cis rs7614311 0.552 rs73117078 chr3:63942084 G/A cg22134162 chr3:63841271 THOC7 -0.47 -5.78 -0.46 5.64e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs7209700 0.777 rs8073827 chr17:45344662 G/T cg21624342 chr17:45890973 OSBPL7 0.19 5.25 0.43 6.39e-7 IgG glycosylation; TGCT cis rs12902680 0.739 rs12438165 chr15:46407408 C/G cg13605988 chr15:45421612 DUOX1;DUOXA1 0.33 4.56 0.38 1.23e-5 Neuroticism; TGCT cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg06640241 chr16:89574553 SPG7 0.8 9.39 0.64 3.77e-16 Multiple myeloma (IgH translocation); TGCT cis rs2153535 0.542 rs9378553 chr6:8472632 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1552244 0.882 rs55962400 chr3:10044457 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.36 -0.5 3.55e-9 Alzheimer's disease; TGCT cis rs7100689 0.646 rs9420370 chr10:82073248 C/T cg01528321 chr10:82214614 TSPAN14 0.75 7.56 0.56 7.74e-12 Post bronchodilator FEV1; TGCT cis rs8180040 0.966 rs6792461 chr3:47473168 C/T cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs8051431 0.876 rs9302633 chr16:72013539 T/C cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs896854 0.812 rs2340586 chr8:95969261 G/A cg13393036 chr8:95962371 TP53INP1 -0.65 -8.82 -0.62 8.57e-15 Type 2 diabetes; TGCT cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT cis rs716804 0.654 rs7924499 chr11:10140797 T/C cg17061862 chr11:9590431 NA -0.34 -4.5 -0.37 1.53e-5 Neuroticism; TGCT cis rs904251 0.600 rs11756241 chr6:37445101 C/T cg08126542 chr6:37504118 NA -0.41 -5.73 -0.46 7.18e-8 Cognitive performance; TGCT cis rs644799 0.511 rs12791736 chr11:95475399 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.59 5.72 0.46 7.49e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9733 0.519 rs6700022 chr1:150670484 G/T cg09365446 chr1:150670422 GOLPH3L -0.29 -4.49 -0.37 1.59e-5 Tonsillectomy; TGCT cis rs9303401 0.659 rs11079358 chr17:56920949 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs12484776 0.735 rs6001799 chr22:40539200 G/A cg07138101 chr22:40742427 ADSL 0.62 4.76 0.39 5.38e-6 Uterine fibroids; TGCT cis rs6582630 0.502 rs10880388 chr12:38401341 A/T cg26384229 chr12:38710491 ALG10B 0.83 7.39 0.55 1.92e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg19045956 chr2:200819837 C2orf60;C2orf47 0.55 5.87 0.47 3.71e-8 Osteoporosis; TGCT cis rs2429369 0.528 rs2526376 chr17:56427142 A/C cg12560992 chr17:57184187 TRIM37 0.64 6.62 0.51 9.89e-10 Cognitive function; TGCT cis rs10751667 0.666 rs7395488 chr11:954111 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs7147624 0.572 rs72714446 chr14:65933144 G/A cg03016385 chr14:66212404 NA 0.6 6.69 0.51 6.88e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs12188164 0.610 rs6555242 chr5:416546 A/C cg22025206 chr5:502436 SLC9A3 -0.24 -4.44 -0.37 1.95e-5 Cystic fibrosis severity; TGCT cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg04352962 chr1:209979756 IRF6 0.61 4.67 0.39 7.72e-6 Cleft lip with or without cleft palate; TGCT cis rs514406 0.505 rs6688064 chr1:53165609 C/T cg25767906 chr1:53392781 SCP2 -0.45 -4.85 -0.4 3.59e-6 Monocyte count; TGCT cis rs67311347 1.000 rs73078164 chr3:40480289 G/A cg13683864 chr3:40499215 RPL14 -1.17 -13.35 -0.77 9.44e-26 Renal cell carcinoma; TGCT cis rs2439831 0.850 rs16977798 chr15:44151948 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs6964587 1.000 rs6952389 chr7:91657994 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs4727027 0.933 rs13225884 chr7:148857795 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.48 4.44 0.37 1.99e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs950776 0.752 rs2869546 chr15:78907345 C/T cg06917634 chr15:78832804 PSMA4 -0.65 -5.3 -0.43 5.01e-7 Sudden cardiac arrest; TGCT cis rs72781680 0.716 rs2712086 chr2:24004739 G/C cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs7714584 1.000 rs10078968 chr5:150244273 C/A cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs735396 1.000 rs1169306 chr12:121438311 C/T cg02403541 chr12:121454288 C12orf43 0.66 6.34 0.49 3.84e-9 N-glycan levels; TGCT cis rs9467773 1.000 rs9467773 chr6:26498426 A/G cg26531700 chr6:26746687 NA 0.46 4.55 0.38 1.27e-5 Intelligence (multi-trait analysis); TGCT cis rs210138 0.882 rs407710 chr6:33554257 A/G cg24505687 chr6:33548425 BAK1 0.45 4.73 0.39 5.98e-6 Testicular germ cell tumor; TGCT cis rs7666738 0.546 rs3911415 chr4:98692401 T/A cg17366294 chr4:99064904 C4orf37 0.61 5.71 0.46 7.81e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.580 rs11635597 chr15:85165699 C/T cg17173187 chr15:85201210 NMB 0.58 6.62 0.51 9.59e-10 Schizophrenia; TGCT cis rs1348850 0.958 rs4243390 chr2:178468008 G/A cg22681709 chr2:178499509 PDE11A -0.39 -4.93 -0.41 2.55e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs769267 0.895 rs2315279 chr19:19479936 C/A cg08509172 chr19:19383838 TM6SF2 0.35 4.66 0.39 7.96e-6 Tonsillectomy; TGCT cis rs644799 1.000 rs516551 chr11:95588626 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 10.59 0.69 4.6e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6754311 0.731 rs1470457 chr2:136581848 A/G cg07169764 chr2:136633963 MCM6 0.73 6.81 0.52 3.81e-10 Mosquito bite size; TGCT cis rs1878931 0.582 rs9921152 chr16:3421199 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 6.35 0.5 3.66e-9 Body mass index (adult); TGCT cis rs763014 0.932 rs2269559 chr16:682297 T/C cg09263875 chr16:632152 PIGQ 0.31 6.89 0.53 2.52e-10 Height; TGCT cis rs1568889 0.838 rs1525717 chr11:28081205 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.35 0.71 6.62e-21 Bipolar disorder; TGCT cis rs6088580 0.634 rs6087579 chr20:32985155 A/G cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs3087591 0.683 rs10512434 chr17:29639590 A/G cg24425628 chr17:29625626 OMG;NF1 -0.33 -4.78 -0.39 4.79e-6 Hip circumference; TGCT cis rs2273156 1.000 rs2273158 chr14:35465784 A/T cg24764865 chr14:36295508 BRMS1L 0.58 4.67 0.39 7.72e-6 Immunoglobulin light chain (AL) amyloidosis; TGCT cis rs6952808 0.575 rs2056479 chr7:1954273 G/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.15 -0.48 9.97e-9 Bipolar disorder and schizophrenia; TGCT cis rs10501293 1.000 rs7111028 chr11:43060516 C/T cg03447554 chr11:43094025 NA 0.46 6.64 0.51 8.85e-10 Cognitive performance; TGCT trans rs797680 0.822 rs1057257 chr1:93621483 A/G cg27528825 chr2:159282178 CCDC148 -0.35 -6.78 -0.52 4.33e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11190604 0.790 rs11190535 chr10:102197441 A/T cg16342193 chr10:102329863 NA -0.41 -5.22 -0.42 7.22e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs28735056 0.563 rs55642704 chr18:77688124 C/T cg05926928 chr17:57297772 GDPD1 -0.67 -6.7 -0.52 6.51e-10 Schizophrenia; TGCT cis rs7781977 0.920 rs7805434 chr7:50340750 G/C cg01139861 chr7:50343298 IKZF1 0.53 5.63 0.45 1.12e-7 IgG glycosylation; TGCT cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg01802117 chr1:53393560 SCP2 0.44 5.34 0.43 4.33e-7 Monocyte count; TGCT cis rs11578119 0.933 rs4423075 chr1:170477349 T/C cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs2730245 0.545 rs2788472 chr7:158649304 T/C cg24397884 chr7:158709396 WDR60 0.37 4.73 0.39 6.11e-6 Height; TGCT cis rs10504229 1.000 rs56740825 chr8:58175617 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2120019 1.000 rs67544533 chr15:75361539 A/G cg09165964 chr15:75287851 SCAMP5 -1.16 -9.79 -0.66 4e-17 Blood trace element (Zn levels); TGCT cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg08392591 chr16:89556376 ANKRD11 0.56 5.15 0.42 1.01e-6 Multiple myeloma (IgH translocation); TGCT cis rs6969780 0.915 rs10085570 chr7:27151188 C/T cg04317399 chr7:27170313 HOXA4 -0.44 -4.87 -0.4 3.3e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs138249 1.000 rs138209 chr22:50539413 T/C cg24864161 chr22:50528282 MOV10L1 0.46 4.95 0.41 2.38e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs3862435 0.572 rs76176014 chr15:90923962 G/A cg14166756 chr15:90894880 ZNF774 -0.32 -5.06 -0.41 1.49e-6 Response to exercise (triglyceride level interaction); TGCT cis rs6570726 1.000 rs1935617 chr6:145943326 C/T cg23711669 chr6:146136114 FBXO30 0.7 6.43 0.5 2.56e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4253772 0.591 rs6007740 chr22:46654323 A/G cg09491104 chr22:46646882 C22orf40 0.61 6.41 0.5 2.82e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs12477438 0.501 rs12995473 chr2:99764884 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs9682041 1.000 rs4955588 chr3:170072864 C/A cg11886554 chr3:170076028 SKIL 0.68 5.37 0.43 3.7e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs2404602 0.669 rs17367297 chr15:77158026 A/C cg22467129 chr15:76604101 ETFA -0.47 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs910316 1.000 rs10149880 chr14:75633008 A/G cg11812906 chr14:75593930 NEK9 -0.75 -7.44 -0.56 1.43e-11 Height; TGCT cis rs367615 0.704 rs55956735 chr5:108845042 A/G cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9894429 0.789 rs8074989 chr17:79598728 G/C cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT cis rs950776 0.593 rs601079 chr15:78869579 T/A cg06917634 chr15:78832804 PSMA4 -0.65 -5.32 -0.43 4.65e-7 Sudden cardiac arrest; TGCT cis rs4665809 1.000 rs6546768 chr2:26328800 A/G cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg08392591 chr16:89556376 ANKRD11 0.57 5.24 0.43 6.61e-7 Multiple myeloma (IgH translocation); TGCT cis rs9807989 0.507 rs6745614 chr2:102991213 A/G cg03938978 chr2:103052716 IL18RAP 0.26 5.22 0.42 7.15e-7 Asthma; TGCT cis rs11696501 0.688 rs1487310 chr20:44308789 A/G cg11783356 chr20:44313418 WFDC10B -0.33 -4.6 -0.38 1.01e-5 Brain structure; TGCT cis rs12220238 0.722 rs11001096 chr10:76413103 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.61 4.76 0.39 5.23e-6 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9467603 1.000 rs9467613 chr6:25812641 T/C cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.585 rs6500441 chr16:89828669 C/G cg27121462 chr16:89883253 FANCA 0.8 8.53 0.61 4.34e-14 Vitiligo; TGCT cis rs7666738 0.753 rs9991512 chr4:99007205 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3733631 0.948 rs3733632 chr4:104640935 A/G cg24090629 chr4:104641072 TACR3 -0.77 -6.29 -0.49 4.9e-9 Menarche (age at onset); TGCT cis rs911263 1.000 rs911263 chr14:68753593 C/T cg18825221 chr14:68749962 RAD51L1 0.28 5.62 0.45 1.22e-7 Primary biliary cholangitis; TGCT cis rs6570726 0.791 rs370112 chr6:145859853 T/G cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7553864 0.614 rs10493796 chr1:87614175 A/G cg17420885 chr1:87600446 LOC339524 0.38 4.86 0.4 3.5e-6 Smoking behavior; TGCT cis rs7267979 1.000 rs4815418 chr20:25382211 T/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.73e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6815814 0.904 rs73236629 chr4:38825449 G/T cg02016764 chr4:38805732 TLR1 -0.29 -4.46 -0.37 1.83e-5 Breast cancer; TGCT cis rs68170813 0.559 rs17427158 chr7:106824259 G/T cg02696742 chr7:106810147 HBP1 -0.7 -6.05 -0.48 1.59e-8 Coronary artery disease; TGCT cis rs651907 0.557 rs3864012 chr3:101397623 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 11.43 0.72 4.08e-21 Colorectal cancer; TGCT cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg04352962 chr1:209979756 IRF6 0.62 4.71 0.39 6.56e-6 Cleft lip with or without cleft palate; TGCT cis rs13256369 0.802 rs12541520 chr8:8564146 G/T cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs17102423 0.723 rs8181939 chr14:65555758 G/A cg11161011 chr14:65562177 MAX -0.55 -7.7 -0.57 3.74e-12 Obesity-related traits; TGCT cis rs6693567 0.565 rs834225 chr1:150300727 T/C cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.02 0.41 1.76e-6 Platelet count; TGCT cis rs56104184 0.779 rs73061627 chr19:49360418 C/T cg17863274 chr19:49399704 TULP2 -0.44 -5.23 -0.42 7.06e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs3849570 0.533 rs6548782 chr3:81993287 T/G cg07356753 chr3:81810745 GBE1 -0.54 -4.51 -0.38 1.49e-5 Waist circumference;Body mass index; TGCT cis rs1552244 0.554 rs13081079 chr3:10056348 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs3733585 0.648 rs67820465 chr4:9975873 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.52 -0.56 9.77e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7552404 1.000 rs1498312 chr1:76177849 C/T cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg00786635 chr1:25594202 NA 0.59 6.09 0.48 1.34e-8 Erythrocyte sedimentation rate; TGCT cis rs7552404 1.000 rs6593585 chr1:76140273 G/A cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6882076 1.000 rs12657266 chr5:156396003 C/T cg12943317 chr5:156479607 HAVCR1 -0.3 -5.59 -0.45 1.38e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs9372498 0.536 rs17424234 chr6:118808521 A/G cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.36e-7 Diastolic blood pressure; TGCT cis rs950776 0.642 rs58946838 chr15:78961449 A/C cg03762349 chr15:79060523 ADAMTS7 0.26 5.05 0.41 1.56e-6 Sudden cardiac arrest; TGCT cis rs9611565 0.694 rs202639 chr22:41856137 T/A cg06634786 chr22:41940651 POLR3H 0.87 8.25 0.6 1.92e-13 Vitiligo; TGCT cis rs3617 0.625 rs2240915 chr3:52859526 T/A cg10802521 chr3:52805072 NEK4 -0.6 -6.89 -0.53 2.46e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7617480 0.648 rs4858800 chr3:48755820 A/G cg07636037 chr3:49044803 WDR6 0.77 6.37 0.5 3.33e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9383153 0.793 rs2016498 chr6:16344914 C/T cg06493612 chr6:15502050 JARID2 0.63 5.58 0.45 1.46e-7 Gambling; TGCT cis rs1799949 1.000 rs33926631 chr17:41304463 T/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs12142240 0.698 rs17413701 chr1:46818452 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg20203395 chr5:56204925 C5orf35 -0.56 -4.8 -0.4 4.39e-6 Initial pursuit acceleration; TGCT cis rs6951245 0.872 rs75280240 chr7:1058511 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.56 -0.38 1.19e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs539096 0.789 rs68191270 chr1:44026180 A/C cg12908607 chr1:44402522 ARTN -0.51 -5.28 -0.43 5.57e-7 Intelligence (multi-trait analysis); TGCT cis rs7044106 0.762 rs1530370 chr9:123424552 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.63 6.68 0.51 7.09e-10 Hip circumference adjusted for BMI; TGCT cis rs4378999 0.702 rs4447760 chr3:50950909 C/T ch.3.1075622R chr3:50010873 RBM6 0.39 4.86 0.4 3.45e-6 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); TGCT cis rs13191362 1.000 rs34653853 chr6:163114362 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.16 9.92 0.67 1.96e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs61897795 0.628 rs174579 chr11:61605613 C/T cg19610905 chr11:61596333 FADS2 -0.88 -6.75 -0.52 5.07e-10 Neutrophil count;Sum basophil neutrophil counts; TGCT cis rs10876993 0.890 rs7976852 chr12:58100551 T/G cg15848620 chr12:58087721 OS9 -0.72 -5.94 -0.47 2.73e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs6994316 0.557 rs1456314 chr8:128075690 A/G cg16485897 chr8:128555993 NA -0.25 -4.67 -0.39 7.67e-6 Prostate cancer; TGCT cis rs10504229 1.000 rs78953746 chr8:58170608 A/G cg21724239 chr8:58056113 NA 0.39 5.24 0.43 6.73e-7 Developmental language disorder (linguistic errors); TGCT trans rs66573146 1.000 rs67067921 chr4:6984341 A/T cg07817883 chr1:32538562 TMEM39B 1.66 8.29 0.6 1.56e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs4654899 1.000 rs4654896 chr1:21356930 T/C cg01072550 chr1:21505969 NA -0.48 -7.78 -0.57 2.49e-12 Superior frontal gyrus grey matter volume; TGCT cis rs1862618 0.853 rs832578 chr5:56164223 C/T cg03609598 chr5:56110824 MAP3K1 -0.59 -4.72 -0.39 6.18e-6 Initial pursuit acceleration; TGCT cis rs6495122 0.644 rs62029217 chr15:75261899 C/T cg10253484 chr15:75165896 SCAMP2 -0.6 -5.51 -0.44 2.02e-7 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs3858526 0.839 rs10466484 chr11:5943696 A/G cg13902645 chr11:5959945 NA -0.44 -4.61 -0.38 9.67e-6 DNA methylation (variation); TGCT cis rs2657888 1.000 rs2657901 chr12:56933416 A/G cg23932658 chr12:57637574 STAC3 0.48 4.57 0.38 1.18e-5 Adiponectin levels; TGCT cis rs854765 0.663 rs3183702 chr17:17747289 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.55 -0.51 1.39e-9 Total body bone mineral density; TGCT cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg07424592 chr7:64974309 NA 1.27 7.86 0.58 1.61e-12 Diabetic kidney disease; TGCT cis rs73058052 0.935 rs3745473 chr19:50086626 T/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.87 7.03 0.53 1.24e-10 Fibrinogen levels; TGCT cis rs968567 0.705 rs174572 chr11:61598288 C/T cg19610905 chr11:61596333 FADS2 -0.99 -9.08 -0.63 2.15e-15 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs523522 0.962 rs11065149 chr12:120956963 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs1887596 0.590 rs608819 chr13:27106141 C/A cg01312412 chr13:27282625 NA -0.28 -4.8 -0.4 4.4e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs3008870 1.000 rs12041926 chr1:67434602 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.06 11.13 0.71 2.26e-20 Lymphocyte percentage of white cells; TGCT cis rs3820068 0.608 rs7516683 chr1:16020502 A/G cg17385448 chr1:15911702 AGMAT -0.35 -4.77 -0.39 5.07e-6 Systolic blood pressure; TGCT cis rs10096908 0.892 rs9886512 chr8:41642164 C/G cg13603914 chr8:41518004 ANK1;MIR486 0.44 4.78 0.39 4.82e-6 Hypertension;Blood pressure traits (multi-trait analysis);Systolic blood pressure; TGCT cis rs9549367 0.789 rs2025247 chr13:113882564 C/G cg18105134 chr13:113819100 PROZ -0.34 -5.45 -0.44 2.63e-7 Platelet distribution width; TGCT cis rs1933488 1.000 rs2119992 chr6:153449670 A/T cg24028809 chr6:153414101 RGS17 0.2 4.53 0.38 1.37e-5 Prostate cancer; TGCT cis rs3784262 0.533 rs12148525 chr15:58196456 A/G cg12031962 chr15:58353849 ALDH1A2 0.51 6.55 0.51 1.38e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg06481639 chr22:41940642 POLR3H -0.66 -5.75 -0.46 6.46e-8 Vitiligo; TGCT cis rs2153535 0.601 rs718504 chr6:8527512 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs10089 0.552 rs1351141 chr5:127550055 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.56 -5.03 -0.41 1.7e-6 Ileal carcinoids; TGCT cis rs9291683 0.588 rs3756236 chr4:10013463 T/A cg02734326 chr4:10020555 SLC2A9 0.38 4.56 0.38 1.22e-5 Bone mineral density; TGCT cis rs916888 0.773 rs199439 chr17:44793503 A/G cg17911788 chr17:44343683 NA -0.65 -6.61 -0.51 1.04e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11785400 1.000 rs4484678 chr8:143730796 A/G cg10596483 chr8:143751796 JRK 0.54 5.77 0.46 5.95e-8 Schizophrenia; TGCT trans rs2688608 0.868 rs2688625 chr10:75631548 T/C cg13918328 chr10:52500089 ASAH2B 0.66 6.85 0.52 3.11e-10 Inflammatory bowel disease; TGCT trans rs11082438 0.786 rs11660485 chr18:42866471 A/C cg13144432 chr15:100513968 ADAMTS17 -0.7 -6.69 -0.51 6.84e-10 Follicular lymphoma; TGCT cis rs9436747 0.641 rs12038998 chr1:66049128 C/A cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.72 0.39 6.28e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7412746 0.563 rs3768013 chr1:150815411 G/A cg04414720 chr1:150670196 GOLPH3L 0.4 4.8 0.4 4.49e-6 Melanoma; TGCT cis rs4455778 0.659 rs2058266 chr7:49015988 G/A cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs1692580 0.777 rs10910037 chr1:2184280 T/C cg24578937 chr1:2090814 PRKCZ 0.24 5.25 0.43 6.42e-7 Coronary artery disease; TGCT cis rs66561647 0.719 rs3739380 chr8:128944507 G/T cg11792826 chr8:129160931 MIR1208 0.21 4.83 0.4 3.93e-6 Hemoglobin concentration; TGCT cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg13395646 chr4:1353034 KIAA1530 -0.41 -4.72 -0.39 6.23e-6 Longevity; TGCT cis rs798554 0.680 rs1713912 chr7:2895784 C/A cg13628971 chr7:2884303 GNA12 0.56 4.6 0.38 1.05e-5 Height; TGCT cis rs12580194 0.593 rs61957924 chr12:55744100 T/C cg10672482 chr12:55725839 OR6C3 -0.52 -4.66 -0.39 8.13e-6 Cancer; TGCT cis rs12210905 0.688 rs79395596 chr6:27490796 C/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs28785552 0.931 rs10406850 chr19:53240807 A/C cg22067481 chr19:53234126 ZNF611 -0.47 -6.7 -0.52 6.59e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs1891275 0.509 rs34190234 chr10:93443074 A/C cg07889827 chr10:93443413 NA -0.33 -6.88 -0.53 2.59e-10 Intelligence (multi-trait analysis); TGCT cis rs17030434 0.953 rs11099905 chr4:154686183 A/G cg14289246 chr4:154710475 SFRP2 0.88 6.58 0.51 1.18e-9 Electrocardiographic conduction measures; TGCT cis rs7258465 1.000 rs10442 chr19:18545341 A/C cg06462663 chr19:18546047 ISYNA1 0.2 4.54 0.38 1.33e-5 Breast cancer; TGCT cis rs7772486 0.754 rs6915718 chr6:146100676 A/G cg13319975 chr6:146136371 FBXO30 0.56 5.01 0.41 1.83e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs629535 1.000 rs644951 chr8:70009082 C/T cg21567404 chr3:27674614 NA -0.56 -8.41 -0.6 8.17e-14 Dupuytren's disease; TGCT cis rs7666738 0.830 rs4699593 chr4:98980628 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.599 rs11181807 chr12:38403763 G/A cg26384229 chr12:38710491 ALG10B -0.52 -4.52 -0.38 1.43e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs56235845 0.694 rs4976643 chr5:176760227 A/C cg06060754 chr5:176797920 RGS14 0.4 6.33 0.49 3.99e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg21280719 chr6:42927975 GNMT -0.37 -4.54 -0.38 1.32e-5 Plasma homocysteine levels (post-methionine load test); TGCT cis rs9400467 0.568 rs12204075 chr6:111489059 G/T cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs2245008 1.000 rs2245008 chr16:83983755 G/A cg27171569 chr16:83987465 OSGIN1 0.57 5.93 0.47 2.82e-8 Pursuit maintenance gain; TGCT cis rs9611565 0.512 rs5751153 chr22:42156561 T/C cg13695892 chr22:41940480 POLR3H 0.87 8.24 0.59 2.06e-13 Vitiligo; TGCT trans rs829418 0.582 rs747662 chr1:21947218 C/G cg24415895 chr10:3598627 NA 0.77 6.7 0.52 6.38e-10 Neurocognitive impairment in HIV-1 infection (continuous); TGCT cis rs9457247 0.967 rs430145 chr6:167410369 C/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs10197940 0.532 rs13425170 chr2:152387112 A/C cg19508488 chr2:152266495 RIF1 0.66 5.79 0.46 5.35e-8 Lung cancer; TGCT cis rs58688157 0.774 rs59115876 chr11:613757 A/G cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs17270561 0.779 rs12209218 chr6:25887776 C/A cg17691542 chr6:26056736 HIST1H1C 0.88 6.05 0.48 1.56e-8 Iron status biomarkers; TGCT cis rs73416724 0.610 rs41275944 chr6:43254597 C/A cg24109273 chr6:43484729 YIPF3;POLR1C 1.15 5.16 0.42 9.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1153858 0.668 rs63603561 chr15:45593323 T/A cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.15 -0.42 9.99e-7 Homoarginine levels; TGCT cis rs6088590 1.000 rs6088607 chr20:33378733 C/T cg24642439 chr20:33292090 TP53INP2 0.69 6.13 0.48 1.09e-8 Coronary artery disease; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.38 5.06 0.41 1.47e-6 Lymphocyte counts; TGCT cis rs12477438 0.520 rs11123764 chr2:99750677 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs2153535 0.580 rs6941771 chr6:8494452 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6938 0.534 rs11854704 chr15:75221015 C/T cg09165964 chr15:75287851 SCAMP5 0.54 4.96 0.41 2.29e-6 Breast cancer; TGCT cis rs2795502 1.000 rs2796575 chr10:43374911 A/G cg20628663 chr10:43360327 NA 0.46 6.56 0.51 1.29e-9 Blood protein levels; TGCT cis rs4319547 1.000 rs7307735 chr12:123087442 A/G cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.44 -0.44 2.69e-7 Body mass index; TGCT cis rs2486288 0.656 rs9921035 chr15:45546660 C/T cg03999130 chr15:45571217 NA -0.51 -4.76 -0.39 5.35e-6 Glomerular filtration rate; TGCT trans rs3780486 0.874 rs10813955 chr9:33141791 C/T cg04842962 chr6:43655489 MRPS18A 1.21 15.08 0.8 7.73e-30 IgG glycosylation; TGCT cis rs16854884 0.837 rs7644767 chr3:143803092 C/G cg06585982 chr3:143692056 C3orf58 0.61 4.72 0.39 6.19e-6 Economic and political preferences (feminism/equality); TGCT cis rs6459788 0.720 rs6965466 chr7:157250749 G/T cg06271696 chr7:157225062 NA -0.27 -5.06 -0.41 1.5e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs523522 0.962 rs687873 chr12:121019634 G/A cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs617219 0.671 rs1316753 chr5:78531337 G/C cg23514016 chr5:78407564 BHMT 0.32 4.86 0.4 3.43e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1401999 1.000 rs10937158 chr3:183708439 T/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs35934224 1.000 rs35934224 chr22:19872645 C/T cg11182965 chr22:19864308 TXNRD2 -0.37 -5.1 -0.42 1.23e-6 Glaucoma (primary open-angle); TGCT cis rs7267979 0.932 rs372678 chr20:25465248 G/A cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1580019 0.961 rs11768506 chr7:32494788 A/C cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs4796354 0.652 rs4377211 chr17:6696047 T/C cg04115740 chr17:6690948 FBXO39 0.25 4.54 0.38 1.33e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs769267 0.929 rs2965180 chr19:19491973 T/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.65 -5.4 -0.44 3.25e-7 Tonsillectomy; TGCT cis rs1215050 0.791 rs2695472 chr4:98855127 T/C cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.18e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9500256 0.967 rs4928431 chr6:58306258 A/G cg16251399 chr6:58287822 GUSBL2 -0.66 -6.19 -0.49 8.21e-9 Eosinophilic esophagitis (pediatric); TGCT cis rs422249 0.512 rs174546 chr11:61569830 C/T cg01500311 chr11:61656094 FADS3 -0.33 -5.6 -0.45 1.3e-7 Trans fatty acid levels; TGCT cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs7926906 0.817 rs7941948 chr11:90527549 C/T cg26138821 chr11:89956704 CHORDC1 -0.52 -5.57 -0.45 1.47e-7 Intelligence (multi-trait analysis); TGCT cis rs6456156 0.819 rs7765739 chr6:167518472 C/T cg07741184 chr6:167504864 NA 0.22 4.44 0.37 2e-5 Primary biliary cholangitis; TGCT cis rs8068544 0.818 rs79892925 chr17:40171819 A/G cg13092355 chr17:39992602 KLHL10;NT5C3L -0.96 -4.47 -0.37 1.72e-5 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs2354432 0.607 rs66486822 chr1:146802653 T/A cg25205988 chr1:146714368 CHD1L -1.41 -5.83 -0.46 4.57e-8 Mitochondrial DNA levels; TGCT trans rs57221529 0.766 rs12519469 chr5:581772 A/G cg11887960 chr12:57824829 NA 1.1 9.83 0.66 3.35e-17 Lung disease severity in cystic fibrosis; TGCT cis rs2070488 0.965 rs13097628 chr3:38521156 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 8.99 0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs2404602 0.583 rs12898415 chr15:76574232 C/T cg26408565 chr15:76604113 ETFA -0.45 -6.35 -0.5 3.66e-9 Blood metabolite levels; TGCT cis rs3849570 0.615 rs9817070 chr3:81982936 A/G cg07356753 chr3:81810745 GBE1 -0.61 -5.3 -0.43 5.08e-7 Waist circumference;Body mass index; TGCT cis rs2153535 0.601 rs2143352 chr6:8530248 G/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs7826238 0.509 rs2948288 chr8:8115304 A/G cg15556689 chr8:8085844 FLJ10661 0.72 6.87 0.53 2.76e-10 Systolic blood pressure; TGCT cis rs611744 0.583 rs1448148 chr8:109333074 T/A cg21045802 chr8:109455806 TTC35 0.82 8.94 0.63 4.53e-15 Dupuytren's disease; TGCT cis rs2120019 0.938 rs35911108 chr15:75322179 G/A cg11632617 chr15:75315747 PPCDC -0.3 -4.44 -0.37 1.95e-5 Blood trace element (Zn levels); TGCT trans rs459571 0.959 rs2810491 chr9:136923331 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 0.72 7.78 0.57 2.47e-12 Platelet distribution width; TGCT cis rs4319547 0.619 rs10744208 chr12:122931559 C/A cg05707623 chr12:122985044 ZCCHC8 -0.71 -5.49 -0.44 2.16e-7 Body mass index; TGCT cis rs1801251 1.000 rs6761324 chr2:233582793 T/G cg08000102 chr2:233561755 GIGYF2 0.63 6.51 0.5 1.72e-9 Coronary artery disease; TGCT cis rs752590 0.945 rs1479 chr2:113975104 T/G cg27425262 chr2:113953981 PSD4;LOC440839 0.42 4.61 0.38 9.75e-6 Mucinous ovarian carcinoma; TGCT cis rs4654899 0.865 rs10916910 chr1:21283192 G/T cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6952808 0.531 rs73039217 chr7:2178731 G/A cg04267008 chr7:1944627 MAD1L1 -0.38 -4.91 -0.4 2.82e-6 Bipolar disorder and schizophrenia; TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT cis rs2013441 1.000 rs2703792 chr17:20166950 G/A cg23224458 chr17:20280056 CCDC144C -0.37 -4.47 -0.37 1.72e-5 Obesity-related traits; TGCT cis rs950169 1.000 rs12915234 chr15:84758301 G/A cg11189052 chr15:85197271 WDR73 0.67 5.68 0.45 9.11e-8 Schizophrenia; TGCT cis rs7937682 0.602 rs4936804 chr11:111743851 A/C cg09085632 chr11:111637200 PPP2R1B 0.88 8.47 0.61 5.93e-14 Primary sclerosing cholangitis; TGCT cis rs12477438 1.000 rs1922624 chr2:99909958 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.81 -0.62 9.23e-15 Chronic sinus infection; TGCT cis rs9811920 0.638 rs793474 chr3:99544380 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -7.02 -0.53 1.32e-10 Axial length; TGCT cis rs7666738 0.546 rs3911415 chr4:98692401 T/A cg18180107 chr4:99064573 C4orf37 0.54 4.78 0.39 4.95e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs921968 0.541 rs10200507 chr2:219335944 C/A cg02176678 chr2:219576539 TTLL4 -0.48 -6.84 -0.52 3.21e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs763121 0.785 rs5757199 chr22:39040617 T/G cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs4509693 1.000 rs6584392 chr10:102497166 G/A cg24127310 chr10:102502104 NA 0.68 5.65 0.45 1.06e-7 Alzheimer's disease; TGCT cis rs9905704 0.647 rs10221208 chr17:57047885 T/C cg12560992 chr17:57184187 TRIM37 0.58 5.16 0.42 9.43e-7 Testicular germ cell tumor; TGCT cis rs28595532 1.000 rs17258106 chr4:119675406 C/T cg21605333 chr4:119757512 SEC24D -1.32 -7.98 -0.58 8.28e-13 Cannabis dependence symptom count; TGCT cis rs6674176 0.628 rs3828146 chr1:44428715 C/T cg13606994 chr1:44402422 ARTN -0.46 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1577917 0.771 rs4419647 chr6:86225739 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.6 5.27 0.43 5.84e-7 Response to antipsychotic treatment; TGCT cis rs7909074 0.966 rs4948645 chr10:45391481 A/G cg05187965 chr10:45406764 TMEM72 -0.23 -5.05 -0.41 1.56e-6 Mean corpuscular volume; TGCT cis rs2777491 0.574 rs11635906 chr15:41779260 A/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -15.65 -0.81 3.87e-31 Ulcerative colitis; TGCT cis rs7588654 1.000 rs7588654 chr2:219983030 C/T cg06736663 chr2:219754761 WNT10A 0.48 4.85 0.4 3.67e-6 Height; TGCT cis rs453301 0.686 rs6987107 chr8:8893581 A/G cg00184457 chr8:8946301 NA -0.26 -4.94 -0.41 2.45e-6 Joint mobility (Beighton score); TGCT cis rs11874712 0.966 rs8093880 chr18:43666786 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs614226 1.000 rs1167727 chr12:120965508 C/A cg01236616 chr12:121019343 POP5 1.26 13.2 0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT trans rs208515 0.525 rs1351866 chr6:66696969 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.33 0.68 1.96e-18 Exhaled nitric oxide levels; TGCT cis rs1008375 0.931 rs6449328 chr4:17700474 C/T cg10189774 chr4:17578691 LAP3 0.52 4.47 0.37 1.73e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9296661 0.868 rs1359676 chr6:51668270 T/A cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs7666738 0.830 rs28417577 chr4:99053007 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.737 rs1497129 chr2:238369184 C/T cg08992911 chr2:238395768 MLPH 0.56 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs200810 0.694 rs17808421 chr6:98013067 A/G cg16511841 chr6:97730490 C6orf167;MIR548H3 0.66 4.62 0.38 9.56e-6 Body mass index; TGCT cis rs2677744 0.626 rs12905855 chr15:91498429 G/C cg22570213 chr15:91497863 RCCD1 0.38 4.61 0.38 9.98e-6 Attention deficit hyperactivity disorder; TGCT cis rs7149242 0.662 rs4905998 chr14:101181781 A/G cg11193865 chr14:101193038 DLK1 -0.47 -5.27 -0.43 5.96e-7 Platelet count; TGCT cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg19318889 chr4:1322082 MAEA 0.17 4.52 0.38 1.45e-5 Obesity-related traits; TGCT cis rs17376456 0.825 rs10078941 chr5:93279029 C/T cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs875971 0.660 rs7807944 chr7:66087195 C/G cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT trans rs1814175 0.817 rs4881627 chr11:49953955 C/A cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs7267979 0.966 rs2261747 chr20:25261784 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1278769 1.000 rs1278769 chr13:113536627 C/T cg17842918 chr13:113540400 ATP11A -0.31 -4.53 -0.38 1.35e-5 Interstitial lung disease; TGCT cis rs13191362 1.000 rs73016459 chr6:163066323 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.86 0.52 2.88e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs17376456 0.569 rs11135397 chr5:93214975 G/T cg25358565 chr5:93447407 FAM172A 0.8 6.53 0.51 1.52e-9 Diabetic retinopathy; TGCT cis rs4906332 1.000 rs4906332 chr14:103980134 A/T cg26031613 chr14:104095156 KLC1 -0.54 -4.66 -0.39 8.15e-6 Coronary artery disease; TGCT cis rs2549003 0.933 rs7719499 chr5:131814091 C/G cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.68e-6 Asthma (sex interaction); TGCT cis rs10949834 0.824 rs2285026 chr7:73530404 C/T cg07137043 chr7:73588983 EIF4H -0.74 -4.53 -0.38 1.38e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs10791097 0.506 rs10750446 chr11:130706918 T/C cg05962950 chr11:130786565 SNX19 -0.61 -6.19 -0.49 7.89e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2296887 0.841 rs12572826 chr10:104132535 C/T cg26089160 chr10:104170217 PSD 0.66 4.66 0.39 8.17e-6 Parkinson's disease; TGCT cis rs9611565 0.559 rs132771 chr22:42025350 A/G cg03806693 chr22:41940476 POLR3H 1.06 11.19 0.71 1.58e-20 Vitiligo; TGCT cis rs752092 0.894 rs8042989 chr15:101770761 T/A cg19997662 chr15:101784653 CHSY1 -0.27 -4.85 -0.4 3.69e-6 Corneal structure; TGCT cis rs7647973 0.961 rs7626076 chr3:49298139 G/A cg06212747 chr3:49208901 KLHDC8B 0.6 4.81 0.4 4.35e-6 Menarche (age at onset); TGCT cis rs2404602 1.000 rs2896954 chr15:76851692 C/A cg26408565 chr15:76604113 ETFA -0.46 -5.92 -0.47 2.98e-8 Blood metabolite levels; TGCT cis rs4242434 0.927 rs11136092 chr8:22466488 T/G cg21658235 chr8:22456391 C8orf58 0.43 4.53 0.38 1.36e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs72945132 0.882 rs66627443 chr11:70199036 C/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs922182 0.633 rs16947621 chr15:64271660 C/G cg02919090 chr15:64263738 DAPK2 0.29 5.24 0.43 6.8e-7 Blood protein levels; TGCT cis rs1580019 0.520 rs13228793 chr7:32711465 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.95 8.78 0.62 1.07e-14 Cognitive ability; TGCT cis rs9303401 0.659 rs17222691 chr17:56771096 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs9902453 0.726 rs3115092 chr17:28036350 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.85 8.57 0.61 3.4e-14 Coffee consumption (cups per day); TGCT cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg22800045 chr5:56110881 MAP3K1 0.54 4.48 0.37 1.69e-5 Initial pursuit acceleration; TGCT cis rs7208859 0.623 rs56163556 chr17:29101868 G/C cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9911578 1.000 rs12453459 chr17:56624291 C/T cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7568458 0.846 rs1078004 chr2:85769711 C/G cg17127132 chr2:85788382 GGCX 0.68 6.59 0.51 1.13e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1008375 1.000 rs11727312 chr4:17669185 C/T cg10189774 chr4:17578691 LAP3 0.58 5.22 0.42 7.16e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2404602 0.716 rs2164101 chr15:76749117 A/G cg26408565 chr15:76604113 ETFA -0.4 -5.26 -0.43 6.23e-7 Blood metabolite levels; TGCT cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg20607798 chr8:58055168 NA 0.47 4.66 0.39 7.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs4919694 0.901 rs12264456 chr10:104830634 C/T cg04362960 chr10:104952993 NT5C2 1.07 7.2 0.54 5.11e-11 Arsenic metabolism; TGCT cis rs250677 0.687 rs42364 chr5:148438858 T/A cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs1205863 1.000 rs1205853 chr6:11942549 T/G cg07106625 chr6:11870215 NA 0.5 5.04 0.41 1.63e-6 Disc degeneration (lumbar); TGCT cis rs1048238 0.506 rs12023422 chr1:16187625 G/A cg21385522 chr1:16154831 NA 0.58 6.49 0.5 1.83e-9 Systolic blood pressure; TGCT cis rs597539 0.690 rs635529 chr11:68626294 C/T cg06112835 chr11:68658793 MRPL21 0.48 8.09 0.59 4.59e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs2865977 chr4:99017916 C/T cg05340658 chr4:99064831 C4orf37 0.47 5.41 0.44 3.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1577917 0.917 rs35738006 chr6:86646309 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs9911578 1.000 rs2567905 chr17:56782297 T/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs6088580 0.634 rs6087588 chr20:33066369 T/C cg06115741 chr20:33292138 TP53INP2 0.54 4.71 0.39 6.47e-6 Glomerular filtration rate (creatinine); TGCT cis rs28374715 0.532 rs28897479 chr15:41690851 T/G cg18705301 chr15:41695430 NDUFAF1 -0.94 -16.83 -0.83 8.04e-34 Ulcerative colitis; TGCT cis rs12477438 0.765 rs6740054 chr2:99576631 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.59 -5.03 -0.41 1.66e-6 Chronic sinus infection; TGCT cis rs4665809 0.590 rs1049987 chr2:26413817 C/T cg25036284 chr2:26402008 FAM59B 0.6 4.64 0.38 8.63e-6 Gut microbiome composition (summer); TGCT cis rs6964587 0.934 rs1544377 chr7:91687351 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs1797081 0.561 rs2603795 chr10:16860256 A/G cg14835575 chr10:16859367 RSU1 0.43 5.5 0.44 2.06e-7 Platelet distribution width; TGCT cis rs7267979 1.000 rs404394 chr20:25447896 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs80282103 0.618 rs2279256 chr10:1132852 G/A cg08668510 chr10:1095578 IDI1 1.07 5.31 0.43 5e-7 Glomerular filtration rate (creatinine); TGCT cis rs9372253 1.000 rs2235989 chr6:110714584 A/T cg01119278 chr6:110721349 DDO -0.35 -5.61 -0.45 1.28e-7 Platelet distribution width; TGCT cis rs7647973 0.925 rs11130183 chr3:49228946 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.57 -4.79 -0.4 4.63e-6 Menarche (age at onset); TGCT cis rs8103278 1.000 rs7258283 chr19:46335511 C/T cg14061069 chr19:46274453 DMPK -0.44 -6.29 -0.49 4.97e-9 Coronary artery disease; TGCT cis rs9534288 0.830 rs1126365 chr13:46633196 T/A cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs10479542 0.702 rs13183521 chr5:178975606 A/G cg21226059 chr5:178986404 RUFY1 -0.45 -4.93 -0.4 2.62e-6 Lung cancer; TGCT cis rs707040 0.843 rs6435170 chr2:155232800 A/C cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs1150668 0.796 rs2531832 chr6:28389222 G/A cg13525197 chr6:28411240 ZSCAN23 -0.51 -4.99 -0.41 1.96e-6 Pubertal anthropometrics; TGCT cis rs2235642 0.826 rs8048410 chr16:1614097 A/G cg07341220 chr16:1583899 IFT140;TMEM204 -0.32 -4.75 -0.39 5.55e-6 Coronary artery disease; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg11905131 chr22:24372483 LOC391322 0.71 5.72 0.46 7.55e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1158570 0.500 rs7846376 chr8:131155443 G/A cg16277922 chr8:131349729 ASAP1 0.45 5.65 0.45 1.04e-7 Platelet count; TGCT cis rs2742417 0.967 rs2742462 chr3:45774696 G/A cg04837898 chr3:45731254 SACM1L -0.53 -5.53 -0.45 1.78e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs3858526 0.628 rs4237762 chr11:5956626 A/C cg05234568 chr11:5960015 NA -0.46 -5.35 -0.43 4.17e-7 DNA methylation (variation); TGCT cis rs11190604 1.000 rs3763695 chr10:102269206 A/G cg23241863 chr10:102295624 HIF1AN 0.67 5.13 0.42 1.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7213347 0.780 rs216224 chr17:2156285 T/C cg22033759 chr17:1182267 TUSC5 0.22 4.51 0.38 1.51e-5 Total body bone mineral density; TGCT cis rs854572 1.000 rs854572 chr7:94954696 C/G cg07404485 chr7:94953653 PON1 -0.3 -5.11 -0.42 1.2e-6 Paraoxonase activity; TGCT cis rs9653442 0.545 rs11681966 chr2:100759457 A/C cg07810366 chr2:100720526 AFF3 0.37 5.42 0.44 3e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7772486 0.686 rs10872579 chr6:145966012 C/G cg23711669 chr6:146136114 FBXO30 0.87 9.51 0.65 1.93e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9426691 1 rs9426691 chr1:23484904 A/G cg12483005 chr1:23474871 LUZP1 0.5 5.84 0.46 4.2e-8 Coenzyme Q10 levels; TGCT cis rs9467711 0.606 rs67509210 chr6:26354100 G/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.765 rs132908 chr22:41801795 G/A cg03806693 chr22:41940476 POLR3H 1.02 11.39 0.72 5.21e-21 Vitiligo; TGCT cis rs71435601 0.628 rs529396 chr2:21381268 G/C cg25035485 chr2:21266500 APOB 0.51 4.49 0.37 1.62e-5 Cholesterol, total; TGCT cis rs2070488 0.574 rs57754356 chr3:38488706 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.8 7.95 0.58 9.86e-13 Electrocardiographic conduction measures; TGCT cis rs10504229 0.953 rs66815941 chr8:58187306 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2729354 0.817 rs2250673 chr11:57268170 T/C cg24343310 chr11:57249947 NA 0.29 4.73 0.39 6.13e-6 Blood protein levels; TGCT cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg00343986 chr7:65444356 GUSB 0.26 5.95 0.47 2.56e-8 Aortic root size; TGCT cis rs2249625 0.584 rs2463744 chr6:72875936 C/T cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs2046867 1.000 rs2046867 chr3:72781075 G/A cg25664220 chr3:72788482 NA -0.55 -6.83 -0.52 3.42e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs6121246 0.821 rs7265413 chr20:30317923 G/A cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs6598955 0.671 rs12090258 chr1:26644698 C/T cg04990556 chr1:26633338 UBXN11 0.62 4.6 0.38 1.04e-5 Obesity-related traits; TGCT cis rs8064299 0.597 rs2166703 chr17:72781812 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.91 10.35 0.68 1.8e-18 Monocyte count; TGCT cis rs7647973 0.600 rs11920267 chr3:49275964 G/A cg03060546 chr3:49711283 APEH 0.54 5.13 0.42 1.11e-6 Menarche (age at onset); TGCT cis rs9972944 0.902 rs12939558 chr17:63772152 A/G cg07283582 chr17:63770753 CCDC46 0.27 5.27 0.43 5.91e-7 Total body bone mineral density; TGCT cis rs9303542 0.694 rs9906950 chr17:46577167 A/G cg25032089 chr17:46643351 HOXB3 -0.52 -5.86 -0.47 3.92e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7267979 0.868 rs6138553 chr20:25239233 G/A cg03522245 chr20:25566470 NINL 0.6 6.45 0.5 2.3e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3782455 1.000 rs77542721 chr12:114402518 C/T cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs10504229 0.683 rs7827014 chr8:58132230 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs17376456 0.809 rs10476602 chr5:93445255 T/C cg25358565 chr5:93447407 FAM172A 0.9 8.26 0.6 1.9e-13 Diabetic retinopathy; TGCT cis rs2235649 0.592 rs8051883 chr16:1958978 G/A cg02432467 chr16:1963432 HS3ST6 -0.31 -4.61 -0.38 9.71e-6 Blood metabolite levels; TGCT cis rs314370 0.951 rs17884589 chr7:100493711 G/A cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg25703541 chr22:24373054 LOC391322 -0.82 -8.62 -0.61 2.61e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs910316 1.000 rs10873275 chr14:75531460 A/T cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs597539 0.652 rs674654 chr11:68698762 G/T cg21862992 chr11:68658383 NA 0.44 6.07 0.48 1.42e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9430161 0.579 rs6694011 chr1:11036935 G/A cg02454025 chr1:11042201 C1orf127 0.92 11.24 0.71 1.21e-20 Ewing sarcoma; TGCT cis rs6684514 1.000 rs12117951 chr1:156305286 G/A cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs12477438 0.715 rs6724476 chr2:99627316 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs8177253 1.000 rs8177271 chr3:133482230 G/A cg08048268 chr3:133502702 NA -0.66 -9.83 -0.66 3.36e-17 Iron status biomarkers; TGCT cis rs9527 0.641 rs4919684 chr10:104587024 A/G cg04362960 chr10:104952993 NT5C2 0.63 5.37 0.43 3.77e-7 Arsenic metabolism; TGCT cis rs1018836 1.000 rs1018836 chr8:91570362 A/G cg16814680 chr8:91681699 NA -0.8 -8.57 -0.61 3.46e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs611744 0.967 rs603571 chr8:109213893 A/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs4851254 0.660 rs4851250 chr2:100729293 T/C cg22139774 chr2:100720529 AFF3 -0.42 -4.45 -0.37 1.85e-5 Intelligence (multi-trait analysis); TGCT cis rs4711350 0.906 rs4713687 chr6:33789402 T/C cg18005901 chr6:33739558 LEMD2 -0.57 -5.75 -0.46 6.68e-8 Schizophrenia; TGCT cis rs12367572 0.504 rs7303573 chr12:45519555 A/C cg04608330 chr12:45269318 NELL2 0.47 4.62 0.38 9.41e-6 Gut microbiome composition (summer); TGCT cis rs2204008 0.805 rs2874289 chr12:38258420 G/A cg13010199 chr12:38710504 ALG10B 0.63 4.92 0.4 2.71e-6 Bladder cancer; TGCT cis rs4148883 0.651 rs2851301 chr4:100010127 C/T cg13256891 chr4:100009986 ADH5 0.42 4.49 0.37 1.64e-5 Alcohol dependence; TGCT cis rs9914988 0.943 rs9915673 chr17:27132893 G/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs73001065 0.901 rs73004962 chr19:19713069 A/T cg03709012 chr19:19516395 GATAD2A 1.04 5.1 0.42 1.26e-6 LDL cholesterol; TGCT cis rs10045504 0.502 rs72746031 chr5:38743161 G/A cg15396434 chr5:38725168 NA -0.35 -4.47 -0.37 1.73e-5 Night sleep phenotypes; TGCT cis rs2050392 0.737 rs7898978 chr10:30699800 T/C cg13289132 chr10:30722225 MAP3K8 0.43 5.33 0.43 4.53e-7 Inflammatory bowel disease; TGCT cis rs9457247 0.935 rs427824 chr6:167403918 T/G cg25258033 chr6:167368657 RNASET2 0.19 4.51 0.38 1.5e-5 Crohn's disease; TGCT cis rs1865760 0.865 rs9467641 chr6:25947236 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT cis rs1371867 0.875 rs2439456 chr8:101336874 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.66 -0.39 8.07e-6 Atrioventricular conduction; TGCT trans rs916888 0.773 rs199448 chr17:44809001 A/G cg10053473 chr17:62856997 LRRC37A3 -0.46 -6.98 -0.53 1.59e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs73110464 0.609 rs727266 chr12:53356411 C/T cg16329197 chr12:53359506 NA -0.56 -7.89 -0.58 1.32e-12 Cancer (pleiotropy); TGCT cis rs6880778 0.505 rs12658567 chr5:40391932 G/T cg01087697 chr5:40835557 RPL37 -0.5 -4.47 -0.37 1.71e-5 Inflammatory bowel disease; TGCT cis rs75686122 0.892 rs77507894 chr8:104580907 T/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg17345569 chr6:42928274 GNMT 0.48 4.97 0.41 2.22e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs854765 0.929 rs854766 chr17:18012775 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.61 5.74 0.46 6.9e-8 Total body bone mineral density; TGCT cis rs2637266 1.000 rs7478008 chr10:78355575 T/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs986417 1.000 rs8021347 chr14:60952773 G/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs7267979 0.586 rs6050445 chr20:25195394 C/T cg14121845 chr20:25566513 NINL 0.45 4.81 0.4 4.26e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg25767906 chr1:53392781 SCP2 0.62 7.81 0.57 2.02e-12 Monocyte count; TGCT cis rs6750047 0.585 rs4670235 chr2:38272528 C/T cg07380506 chr2:38303506 CYP1B1 0.59 5.36 0.43 3.84e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs17125944 0.686 rs7144029 chr14:53333616 G/T cg00686598 chr14:53173677 PSMC6 -0.86 -4.47 -0.37 1.75e-5 Alzheimer's disease (late onset); TGCT cis rs8084351 0.902 rs7245004 chr18:50716945 C/A cg24270629 chr18:50823537 DCC -0.28 -4.61 -0.38 1e-5 Subjective well-being (multi-trait analysis);Depressive symptoms (multi-trait analysis);Neuroticism (multi-trait analysis); TGCT cis rs7312933 0.526 rs1669892 chr12:42811305 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.69 -0.46 8.61e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10504229 0.906 rs56130194 chr8:58197061 C/A cg22535103 chr8:58192502 C8orf71 -0.44 -5.25 -0.43 6.36e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs62318472 chr4:98926030 G/A cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.8e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6461049 0.638 rs1859993 chr7:2183702 A/G cg22963979 chr7:1858916 MAD1L1 -0.41 -6.75 -0.52 4.97e-10 Schizophrenia; TGCT cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs11098499 0.619 rs28502463 chr4:120257023 T/C cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Corneal astigmatism; TGCT cis rs7027203 1.000 rs7864114 chr9:96551954 A/G cg14598338 chr9:96623480 NA 0.59 8.65 0.61 2.17e-14 DNA methylation (variation); TGCT cis rs7666738 0.830 rs11097598 chr4:98946057 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs17685 0.712 rs4552844 chr7:75718095 A/G cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1552244 1.000 rs66797209 chr3:10078526 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs13191362 0.872 rs13206549 chr6:162978032 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.65 5.31 0.43 4.94e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2013441 1.000 rs2526458 chr17:20092200 C/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg03517284 chr6:25882590 NA 0.89 9.16 0.64 1.32e-15 Blood metabolite levels; TGCT cis rs9811920 0.809 rs4928151 chr3:99767553 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.18 0.42 8.61e-7 Axial length; TGCT cis rs2580764 0.573 rs13387751 chr2:55227375 C/G cg09592903 chr2:55203963 RTN4 -0.24 -5.32 -0.43 4.73e-7 Mean platelet volume; TGCT cis rs1577917 1.000 rs12216203 chr6:86675301 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.48 -0.44 2.27e-7 Response to antipsychotic treatment; TGCT trans rs2469997 1.000 rs2470021 chr8:120362644 T/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs2067615 0.560 rs10431462 chr12:107106546 G/A cg15890332 chr12:107067104 RFX4 0.3 5.88 0.47 3.6e-8 Heart rate; TGCT cis rs6923462 0.642 rs13209685 chr6:7779729 G/T cg16988958 chr6:7987739 MGC26597 0.26 4.52 0.38 1.4e-5 Lung function (forced vital capacity); TGCT cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg13695892 chr22:41940480 POLR3H 0.91 9.32 0.64 5.63e-16 Vitiligo; TGCT cis rs76473307 1.000 rs76473307 chr20:57406068 A/C cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs116095464 0.558 rs62346526 chr5:220614 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs6570726 0.599 rs4398765 chr6:145935006 C/A cg13319975 chr6:146136371 FBXO30 -0.68 -6.23 -0.49 6.81e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg11062466 chr8:58055876 NA 0.46 4.88 0.4 3.25e-6 Developmental language disorder (linguistic errors); TGCT cis rs10540 0.730 rs61876338 chr11:493730 A/G cg03352830 chr11:487213 PTDSS2 0.26 4.56 0.38 1.23e-5 Body mass index; TGCT cis rs72720396 0.803 rs114993052 chr1:91190855 T/A cg13456504 chr1:91191583 NA 0.74 5.83 0.46 4.57e-8 Morning vs. evening chronotype;Chronotype; TGCT cis rs7940866 0.804 rs3910267 chr11:130810282 C/T cg12179176 chr11:130786555 SNX19 0.59 5.82 0.46 4.62e-8 Schizophrenia; TGCT cis rs9300255 0.602 rs1790131 chr12:123701010 G/T cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs3806843 0.576 rs246046 chr5:140329264 T/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9486719 0.843 rs976357 chr6:96849679 C/T cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs7172809 0.500 rs17385059 chr15:77637812 T/C cg22256960 chr15:77711686 NA -0.51 -4.81 -0.4 4.29e-6 Glucose homeostasis traits; TGCT cis rs8056742 0.642 rs60115438 chr16:85047240 T/G cg00229868 chr16:85520891 NA 0.4 5.09 0.42 1.3e-6 Amyotrophic lateral sclerosis; TGCT cis rs1018836 0.699 rs13271657 chr8:91474599 C/G cg16814680 chr8:91681699 NA -0.85 -8.36 -0.6 1.1e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT trans rs1814175 0.817 rs10839465 chr11:49981554 C/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs739401 0.611 rs7130841 chr11:3043658 A/G cg25174290 chr11:3078921 CARS 0.47 4.68 0.39 7.52e-6 Longevity; TGCT cis rs2836950 0.565 rs2836931 chr21:40546569 T/G cg11644478 chr21:40555479 PSMG1 -0.54 -4.89 -0.4 3.02e-6 Menarche (age at onset); TGCT cis rs1865760 0.865 rs9467651 chr6:25958257 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs9311474 0.508 rs7614498 chr3:52618941 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.09 -0.42 1.29e-6 Electroencephalogram traits; TGCT cis rs2735413 0.564 rs2344492 chr16:78096226 C/T cg09132178 chr16:78079569 NA 0.33 4.44 0.37 1.98e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs7267979 0.966 rs2257461 chr20:25265554 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 0.844 rs6050477 chr20:25221547 C/T cg03522245 chr20:25566470 NINL -0.55 -5.95 -0.47 2.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3806843 0.648 rs702399 chr5:140024432 C/T cg19875535 chr5:140030758 IK -0.35 -6.27 -0.49 5.41e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs10823500 0.777 rs7919014 chr10:71944577 T/C cg04118878 chr10:71993077 PPA1 0.54 4.96 0.41 2.3e-6 Blood protein levels; TGCT cis rs919433 0.713 rs13411968 chr2:198467141 C/T cg00792783 chr2:198669748 PLCL1 0.48 4.47 0.37 1.75e-5 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs2370759 1.000 rs78959390 chr10:32616346 C/T cg01819863 chr10:32635814 EPC1 1.03 10.0 0.67 1.27e-17 Sexual dysfunction (female); TGCT cis rs9291683 0.597 rs11723016 chr4:10126189 A/G cg11266682 chr4:10021025 SLC2A9 -0.44 -5.33 -0.43 4.44e-7 Bone mineral density; TGCT cis rs6952808 0.609 rs6970034 chr7:1948088 G/A cg04267008 chr7:1944627 MAD1L1 -0.37 -4.83 -0.4 3.94e-6 Bipolar disorder and schizophrenia; TGCT cis rs7772486 0.754 rs4896839 chr6:146019689 T/G cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs7113874 0.531 rs10840094 chr11:8627974 T/A cg14521421 chr11:8862019 ST5 -0.3 -4.61 -0.38 1e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs4665809 0.941 rs41285975 chr2:26351144 T/C cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs35146811 0.735 rs1727130 chr7:99811464 C/G cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs9372498 0.536 rs9489442 chr6:118885950 A/C cg07617317 chr6:118971624 C6orf204 0.52 5.54 0.45 1.71e-7 Diastolic blood pressure; TGCT cis rs11754661 1.000 rs78944278 chr6:151207454 C/T cg01354656 chr6:151411710 MTHFD1L 0.48 4.46 0.37 1.81e-5 Alzheimer's disease (late onset); TGCT cis rs10256972 0.721 rs10435145 chr7:1065988 C/T cg03188948 chr7:1209495 NA 0.5 6.74 0.52 5.38e-10 Longevity;Endometriosis; TGCT cis rs7586879 0.789 rs13382979 chr2:25131736 G/A cg01884057 chr2:25150051 NA 0.27 4.64 0.38 8.78e-6 Body mass index; TGCT cis rs7937682 0.889 rs1789355 chr11:111499718 T/C cg09085632 chr11:111637200 PPP2R1B -1.11 -11.7 -0.72 9.24e-22 Primary sclerosing cholangitis; TGCT cis rs35306767 0.903 rs11253467 chr10:901244 A/G cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs5769765 0.825 rs7511620 chr22:50307932 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.22 -12.54 -0.75 8.41e-24 Schizophrenia; TGCT cis rs10875746 0.669 rs61940962 chr12:48595477 A/C cg20731937 chr12:48336164 NA 0.6 4.6 0.38 1.01e-5 Longevity (90 years and older); TGCT cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.24 0.49 6.39e-9 Schizophrenia; TGCT cis rs6088580 0.634 rs6120650 chr20:33039973 G/A cg08999081 chr20:33150536 PIGU 0.29 5.74 0.46 6.96e-8 Glomerular filtration rate (creatinine); TGCT cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg23719950 chr11:63933701 MACROD1 0.64 5.64 0.45 1.07e-7 Mean platelet volume; TGCT cis rs9486715 0.830 rs2475023 chr6:96996833 G/A cg06623918 chr6:96969491 KIAA0776 -1.1 -14.35 -0.79 3.93e-28 Headache; TGCT cis rs9650657 0.515 rs6601560 chr8:10950866 T/C cg03192020 chr8:11204681 TDH -0.52 -4.52 -0.38 1.42e-5 Neuroticism; TGCT cis rs7552404 0.924 rs1146588 chr1:76229787 C/G cg10523679 chr1:76189770 ACADM 0.82 8.79 0.62 1.05e-14 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9486719 0.857 rs4265039 chr6:96878929 T/C cg18709589 chr6:96969512 KIAA0776 0.76 6.58 0.51 1.19e-9 Migraine;Coronary artery disease; TGCT cis rs11671005 0.693 rs11669665 chr19:58931885 G/A cg13877915 chr19:58951672 ZNF132 0.65 5.14 0.42 1.04e-6 Mean platelet volume; TGCT cis rs2637266 0.846 rs2637263 chr10:78322442 G/A cg18941641 chr10:78392320 NA 0.39 4.94 0.41 2.45e-6 Pulmonary function; TGCT cis rs3008870 0.583 rs3008861 chr1:67396222 T/G cg11518657 chr1:67396239 MIER1 0.59 4.69 0.39 7.23e-6 Lymphocyte percentage of white cells; TGCT cis rs7833790 0.963 rs7836040 chr8:82698328 G/A cg27398817 chr8:82754497 SNX16 -0.81 -5.62 -0.45 1.22e-7 Diastolic blood pressure; TGCT cis rs10782582 0.593 rs12131344 chr1:76136437 C/T cg22875332 chr1:76189707 ACADM -0.55 -6.04 -0.48 1.68e-8 Daytime sleep phenotypes; TGCT cis rs7727544 0.716 rs6863213 chr5:131575932 C/T cg24060327 chr5:131705240 SLC22A5 -0.57 -5.6 -0.45 1.3e-7 Blood metabolite levels; TGCT cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg11644478 chr21:40555479 PSMG1 1.02 10.63 0.69 3.73e-19 Cognitive function; TGCT cis rs854765 0.583 rs4341796 chr17:17839024 C/A cg09796270 chr17:17721594 SREBF1 0.27 5.55 0.45 1.69e-7 Total body bone mineral density; TGCT cis rs4944092 1.000 rs4944092 chr11:75909619 C/T cg04588336 chr11:75916460 WNT11 -0.46 -6.36 -0.5 3.56e-9 PR interval; TGCT cis rs1372520 0.684 rs356188 chr4:90691537 T/C cg20003494 chr4:90757398 SNCA 0.56 4.46 0.37 1.83e-5 Neuroticism; TGCT cis rs3820928 0.839 rs13404750 chr2:227876129 G/A cg11843606 chr2:227700838 RHBDD1 -0.52 -4.62 -0.38 9.54e-6 Pulmonary function; TGCT cis rs881375 0.678 rs7021049 chr9:123683982 G/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.47 5.18 0.42 8.53e-7 Rheumatoid arthritis; TGCT cis rs5750830 0.649 rs4821895 chr22:39823015 A/G cg01416388 chr22:39784598 NA -0.72 -7.14 -0.54 6.88e-11 Intelligence (multi-trait analysis); TGCT cis rs9796 0.775 rs57393155 chr15:41426251 A/G cg18705301 chr15:41695430 NDUFAF1 -0.47 -5.99 -0.47 2.14e-8 Menopause (age at onset); TGCT cis rs12477438 0.501 rs2516833 chr2:99777405 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs17221829 0.733 rs10765228 chr11:89385132 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs116161686 0.500 rs55871867 chr1:210051029 A/G cg21951975 chr1:209979733 IRF6 0.63 4.96 0.41 2.23e-6 Coronary artery disease; TGCT cis rs9291683 0.546 rs13120348 chr4:10053155 C/G cg11266682 chr4:10021025 SLC2A9 -0.61 -7.76 -0.57 2.7e-12 Bone mineral density; TGCT cis rs514406 0.861 rs1749907 chr1:53259658 C/T cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs6500602 0.634 rs2270365 chr16:4526758 G/A cg08645402 chr16:4508243 NA 0.17 4.84 0.4 3.86e-6 Schizophrenia; TGCT cis rs3785574 0.962 rs2597632 chr17:61894739 A/T cg11494091 chr17:61959527 GH2 0.43 7.4 0.55 1.82e-11 Height; TGCT cis rs28453840 1 rs28453840 chr2:136522941 G/A cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Cholesterol, total; TGCT cis rs3772130 0.923 rs3805127 chr3:121556751 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs7267979 0.789 rs9927 chr20:25277244 A/G cg14121845 chr20:25566513 NINL 0.48 4.86 0.4 3.43e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3806843 0.548 rs246055 chr5:140325662 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT trans rs459571 0.959 rs392134 chr9:136909008 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.75 -8.08 -0.59 4.97e-13 Platelet distribution width; TGCT cis rs254781 0.550 rs410216 chr5:88004101 G/A cg22951263 chr5:87985283 NA -0.56 -5.05 -0.41 1.51e-6 Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs3807993 chr7:116197572 T/A cg16553024 chr7:116138462 CAV2 -0.43 -5.19 -0.42 8.16e-7 P wave duration; TGCT trans rs7726839 0.540 rs72703092 chr5:599269 G/A cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs9467773 0.587 rs12214031 chr6:26376628 T/C cg15659132 chr6:26577336 NA -0.52 -5.27 -0.43 5.83e-7 Intelligence (multi-trait analysis); TGCT cis rs7681440 0.904 rs3756063 chr4:90757394 G/C cg20003494 chr4:90757398 SNCA -0.61 -5.78 -0.46 5.8e-8 Dementia with Lewy bodies; TGCT cis rs6088590 0.965 rs6058108 chr20:33288655 A/G cg06115741 chr20:33292138 TP53INP2 0.65 5.49 0.44 2.17e-7 Coronary artery disease; TGCT cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 8.11 0.59 4.07e-13 Platelet count; TGCT cis rs9660180 0.967 rs10907191 chr1:1774820 A/T cg03396347 chr1:1875803 NA -0.37 -6.7 -0.52 6.62e-10 Body mass index; TGCT cis rs79387448 0.614 rs985523 chr2:102954376 G/A cg09003973 chr2:102972529 NA 1.34 10.63 0.69 3.78e-19 Gut microbiota (bacterial taxa); TGCT cis rs2019216 0.521 rs6565386 chr17:21901755 A/G cg22648282 chr17:21454238 C17orf51 0.56 5.53 0.45 1.78e-7 Pelvic organ prolapse; TGCT cis rs9894429 1.000 rs7209180 chr17:79581519 C/A cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs2469997 1.000 rs2447181 chr8:120354288 T/A cg00681363 chr8:120844660 TAF2 0.65 4.52 0.38 1.45e-5 Hypertension (SNP x SNP interaction); TGCT cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg06640241 chr16:89574553 SPG7 0.82 9.41 0.65 3.39e-16 Multiple myeloma (IgH translocation); TGCT cis rs9399135 0.967 rs12527683 chr6:135324534 C/T cg24558204 chr6:135376177 HBS1L 0.47 4.75 0.39 5.58e-6 Red blood cell count; TGCT cis rs4555082 0.957 rs8022526 chr14:105756485 A/G cg10792982 chr14:105748885 BRF1 0.22 4.5 0.37 1.57e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs9435341 0.965 rs55909997 chr1:107581039 G/A cg09367891 chr1:107599246 PRMT6 0.64 5.71 0.46 7.78e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs7267979 0.866 rs437635 chr20:25456888 A/G cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg01585852 chr22:24235823 MIF -0.22 -4.82 -0.4 4.16e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11676348 0.755 rs6436026 chr2:218951738 T/A cg00012203 chr2:219082015 ARPC2 -0.5 -4.63 -0.38 8.99e-6 Ulcerative colitis; TGCT cis rs6684514 0.961 rs12048077 chr1:156299916 T/A cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs17345786 0.861 rs11707689 chr3:101086475 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.84 8.92 0.63 5.05e-15 Colonoscopy-negative controls vs population controls; TGCT cis rs10089 1.000 rs4836367 chr5:127482592 A/G cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.27e-5 Ileal carcinoids; TGCT trans rs7726839 0.574 rs12522955 chr5:639231 C/A cg11887960 chr12:57824829 NA 1.14 9.28 0.64 6.87e-16 Obesity-related traits; TGCT cis rs1018836 0.828 rs1858673 chr8:91551526 C/A cg16814680 chr8:91681699 NA -0.75 -7.83 -0.58 1.84e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7618915 0.501 rs2109634 chr3:52752075 T/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs9500256 0.683 rs10458024 chr6:58324089 T/C cg16251399 chr6:58287822 GUSBL2 0.53 4.47 0.37 1.72e-5 Eosinophilic esophagitis (pediatric); TGCT cis rs765787 0.530 rs12913123 chr15:45516425 C/T cg24006582 chr15:45444508 DUOX1 0.25 5.33 0.43 4.46e-7 Uric acid levels; TGCT cis rs6964587 1.000 rs411 chr7:91557758 C/G cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs9357506 1.000 rs6910772 chr6:46307395 C/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs9388451 0.839 rs10457469 chr6:126083658 G/A cg10911889 chr6:126070802 HEY2 0.54 5.64 0.45 1.08e-7 Brugada syndrome; TGCT cis rs854765 0.505 rs4924832 chr17:17897739 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.06 0.59 5.4e-13 Total body bone mineral density; TGCT cis rs2243480 1.000 rs36033484 chr7:65390558 T/G cg18252515 chr7:66147081 NA -1.14 -6.81 -0.52 3.76e-10 Diabetic kidney disease; TGCT cis rs734999 0.545 rs10797436 chr1:2538349 G/A cg18854424 chr1:2615690 NA 0.41 4.58 0.38 1.13e-5 Ulcerative colitis; TGCT cis rs860295 0.540 rs915178 chr1:155978725 C/T cg05700447 chr1:155978627 NA 0.24 5.09 0.42 1.28e-6 Body mass index; TGCT cis rs514406 0.505 rs12726160 chr1:53175099 A/G cg08859206 chr1:53392774 SCP2 -0.37 -5.39 -0.44 3.4e-7 Monocyte count; TGCT cis rs892961 0.806 rs35489990 chr17:75412312 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs8084125 0.832 rs62105166 chr18:74944518 A/G cg05528293 chr18:74961138 GALR1 0.49 4.84 0.4 3.74e-6 Obesity-related traits; TGCT cis rs6901004 0.771 rs6900781 chr6:111422856 T/A cg15721981 chr6:111408429 SLC16A10 -0.53 -4.62 -0.38 9.3e-6 Blood metabolite levels; TGCT cis rs7178572 0.524 rs7163503 chr15:77493505 C/A cg22256960 chr15:77711686 NA -0.88 -8.99 -0.63 3.53e-15 Type 2 diabetes; TGCT cis rs3764628 0.925 rs11670437 chr19:18783390 C/T cg20098710 chr19:19640075 YJEFN3 -0.46 -5.23 -0.42 7.11e-7 Orofacial clefts; TGCT cis rs8017423 0.967 rs1959002 chr14:90670994 T/A cg04374321 chr14:90722782 PSMC1 0.77 7.95 0.58 9.78e-13 Mortality in heart failure; TGCT cis rs9372498 0.536 rs9489457 chr6:118920285 C/T cg07617317 chr6:118971624 C6orf204 0.49 5.22 0.42 7.37e-7 Diastolic blood pressure; TGCT cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg10047753 chr17:41438598 NA 0.94 9.17 0.64 1.28e-15 Menopause (age at onset); TGCT cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs6570726 0.791 rs378937 chr6:145834745 C/T cg23711669 chr6:146136114 FBXO30 0.82 8.59 0.61 3.08e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs6714710 0.580 rs1838797 chr2:98454572 G/C cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs9311474 0.967 rs11717383 chr3:52287468 G/T cg07507251 chr3:52567010 NT5DC2 0.43 6.0 0.47 2e-8 Electroencephalogram traits; TGCT cis rs7208859 0.623 rs8082537 chr17:29015932 T/C cg13385521 chr17:29058706 SUZ12P 0.75 4.62 0.38 9.34e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9443645 0.901 rs4706079 chr6:79615208 G/A cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.904 rs9900974 chr17:28364456 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.47e-12 Coffee consumption (cups per day); TGCT cis rs782590 0.935 rs62165197 chr2:55801812 C/T cg18811423 chr2:55921094 PNPT1 0.65 6.93 0.53 2.04e-10 Metabolic syndrome; TGCT cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs921968 0.643 rs598701 chr2:219387005 C/G cg02176678 chr2:219576539 TTLL4 -0.38 -5.48 -0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs17221829 0.692 rs2773236 chr11:89454836 C/T cg02982614 chr11:89391479 FOLH1B -0.27 -4.88 -0.4 3.23e-6 Anxiety in major depressive disorder; TGCT cis rs9311474 0.935 rs7622851 chr3:52333671 C/G cg07507251 chr3:52567010 NT5DC2 0.46 6.21 0.49 7.16e-9 Electroencephalogram traits; TGCT cis rs4689388 0.890 rs11732208 chr4:6292716 G/C cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6582630 0.512 rs11182667 chr12:38588392 C/A cg26384229 chr12:38710491 ALG10B -0.54 -4.75 -0.39 5.62e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs10540 0.570 rs8176330 chr11:535798 G/A cg03934478 chr11:495069 RNH1 0.32 4.55 0.38 1.28e-5 Body mass index; TGCT cis rs6582630 0.533 rs4103689 chr12:38702980 A/C cg26384229 chr12:38710491 ALG10B 0.68 6.28 0.49 5.18e-9 Drug-induced liver injury (flucloxacillin); TGCT cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs10927875 0.541 rs1739841 chr1:16342727 A/G cg22431228 chr1:16359049 CLCNKA -0.29 -6.02 -0.48 1.8e-8 Dilated cardiomyopathy; TGCT cis rs9633740 1.000 rs6586028 chr10:82253984 C/T cg01528321 chr10:82214614 TSPAN14 1.02 8.53 0.61 4.31e-14 Post bronchodilator FEV1; TGCT cis rs16957091 0.607 rs7182650 chr15:43342878 T/A cg17935677 chr15:44119062 WDR76 0.56 4.9 0.4 2.93e-6 MGMT methylation in smokers; TGCT cis rs36051895 0.626 rs10283564 chr9:5075628 C/G cg02405213 chr9:5042618 JAK2 -0.79 -10.23 -0.68 3.48e-18 Pediatric autoimmune diseases; TGCT cis rs7618915 0.501 rs3733045 chr3:52643307 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.62 5.93 0.47 2.86e-8 Bipolar disorder; TGCT cis rs4689388 0.926 rs4458523 chr4:6289986 G/T cg14416269 chr4:6271139 WFS1 -0.37 -4.88 -0.4 3.15e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2933343 0.909 rs1683817 chr3:128651536 G/A cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs3020736 0.500 rs6002604 chr22:42493081 A/T cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9381040 0.610 rs6919961 chr6:41020361 T/A cg03526776 chr6:41159608 TREML2 0.27 5.43 0.44 2.89e-7 Alzheimer's disease (late onset); TGCT cis rs2404602 0.692 rs2137307 chr15:77149020 T/A cg22467129 chr15:76604101 ETFA -0.47 -5.4 -0.44 3.28e-7 Blood metabolite levels; TGCT cis rs4975616 0.686 rs37008 chr5:1351538 C/T cg26373071 chr5:1325741 CLPTM1L 0.19 5.03 0.41 1.68e-6 Lung cancer; TGCT cis rs6570726 1.000 rs1935615 chr6:145921117 G/T cg23711669 chr6:146136114 FBXO30 0.65 5.96 0.47 2.4e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs62064224 0.554 rs9901737 chr17:30681354 C/G cg18200150 chr17:30822561 MYO1D 0.39 4.72 0.39 6.34e-6 Schizophrenia; TGCT trans rs10802346 0.515 rs1113270 chr1:246423217 A/G cg22732515 chr19:44031385 ETHE1 0.96 8.12 0.59 3.9e-13 Fractional exhaled nitric oxide (childhood); TGCT cis rs1372520 0.748 rs2737002 chr4:90753180 A/G cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs3096299 0.563 rs4600467 chr16:89562516 C/T cg06640241 chr16:89574553 SPG7 0.84 9.55 0.65 1.55e-16 Multiple myeloma (IgH translocation); TGCT cis rs17221829 0.733 rs10830304 chr11:89366754 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs4900538 0.963 rs1998422 chr14:102980993 G/C cg18135206 chr14:102964638 TECPR2 0.22 5.1 0.42 1.22e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs769267 0.930 rs4808955 chr19:19552413 T/C cg08509172 chr19:19383838 TM6SF2 -0.36 -4.76 -0.39 5.28e-6 Tonsillectomy; TGCT cis rs7119 0.651 rs8041520 chr15:77839169 C/T cg27398640 chr15:77910606 LINGO1 -0.27 -5.1 -0.42 1.22e-6 Type 2 diabetes; TGCT cis rs4819852 0.958 rs2238792 chr22:19983213 C/T cg07821417 chr22:19972146 ARVCF 0.19 4.8 0.4 4.42e-6 Pulse pressure; TGCT cis rs9653442 0.564 rs2309756 chr2:100780269 G/C cg22139774 chr2:100720529 AFF3 -0.36 -5.69 -0.46 8.67e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7829975 0.577 rs940030 chr8:8546928 A/G cg17143192 chr8:8559678 CLDN23 -0.52 -5.26 -0.43 6.11e-7 Mood instability; TGCT cis rs56104184 0.775 rs73061695 chr19:49399988 T/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs12580194 1.000 rs12582022 chr12:55694360 A/G cg20672549 chr12:56432144 IKZF4 0.28 4.52 0.38 1.44e-5 Cancer; TGCT cis rs7772486 0.777 rs1546966 chr6:146386018 G/T cg05347473 chr6:146136440 FBXO30 0.5 4.43 0.37 2.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs912057 0.582 rs1294412 chr6:6739854 A/G cg06612196 chr6:6737390 NA 0.5 7.47 0.56 1.24e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9308731 0.863 rs17558117 chr2:111940996 A/T cg04202892 chr2:111875749 ACOXL 0.47 5.13 0.42 1.08e-6 Chronic lymphocytic leukemia; TGCT cis rs72843506 0.722 rs74255392 chr17:20329052 A/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.78 -0.39 4.96e-6 Schizophrenia; TGCT cis rs7829975 0.688 rs7826660 chr8:8379107 C/A cg06636001 chr8:8085503 FLJ10661 0.77 7.37 0.55 2.12e-11 Mood instability; TGCT cis rs6087990 0.806 rs4911254 chr20:31357579 C/A cg13636640 chr20:31349939 DNMT3B 1.07 14.14 0.79 1.28e-27 Ulcerative colitis; TGCT cis rs9611519 0.780 rs9611528 chr22:41648502 T/C cg03806693 chr22:41940476 POLR3H -0.73 -6.97 -0.53 1.67e-10 Neuroticism; TGCT cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg26119090 chr2:26468346 HADHA;HADHB -0.99 -7.28 -0.55 3.39e-11 Gut microbiome composition (summer); TGCT cis rs35883536 0.584 rs56112014 chr1:101037431 A/G cg06223162 chr1:101003688 GPR88 -0.41 -7.56 -0.56 7.75e-12 Monocyte count; TGCT cis rs116095464 0.558 rs10057674 chr5:266813 C/T cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs6088580 0.634 rs6059850 chr20:33044784 C/G cg06115741 chr20:33292138 TP53INP2 0.55 4.69 0.39 7.24e-6 Glomerular filtration rate (creatinine); TGCT cis rs7617773 0.925 rs35942721 chr3:48173069 C/T cg11946769 chr3:48343235 NME6 0.67 5.34 0.43 4.26e-7 Coronary artery disease; TGCT cis rs2492301 0.540 rs10796907 chr1:37900173 C/T cg17933807 chr1:38061675 GNL2 0.59 6.21 0.49 7.24e-9 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12477438 0.765 rs7605734 chr2:99644068 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs2836974 0.644 rs11088471 chr21:40699313 A/G cg11644478 chr21:40555479 PSMG1 -0.53 -4.57 -0.38 1.17e-5 Cognitive function; TGCT cis rs11864453 0.647 rs3764311 chr16:72125617 C/G cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs477895 1.000 rs7938380 chr11:64034866 G/A cg04317338 chr11:64019027 PLCB3 0.71 5.75 0.46 6.48e-8 Mean platelet volume; TGCT cis rs6089584 0.526 rs6089316 chr20:60627552 C/T cg13770153 chr20:60521292 NA -0.39 -4.61 -0.38 9.96e-6 Body mass index; TGCT cis rs2014572 0.967 rs10412975 chr19:57770554 C/A cg24459738 chr19:57751996 ZNF805 -0.59 -5.79 -0.46 5.52e-8 Hyperactive-impulsive symptoms; TGCT cis rs6088590 1.000 rs6058111 chr20:33310999 T/C cg24642439 chr20:33292090 TP53INP2 0.69 6.01 0.48 1.88e-8 Coronary artery disease; TGCT cis rs7226408 0.749 rs11665002 chr18:34314023 C/T cg06757138 chr18:34340585 FHOD3 0.27 4.86 0.4 3.48e-6 Obesity-related traits; TGCT cis rs78487399 0.808 rs28700209 chr2:43667465 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7937612 1.000 rs4938808 chr11:120336902 G/T cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.48 -0.37 1.66e-5 Intraocular pressure; TGCT cis rs10779751 0.770 rs2791643 chr1:11207269 C/T cg08854313 chr1:11322531 MTOR 0.82 6.66 0.51 7.99e-10 Body mass index; TGCT cis rs9399135 0.967 rs6902438 chr6:135336587 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs9302065 0.565 rs2993585 chr13:95961966 G/A cg24476569 chr13:95954382 ABCC4 -0.54 -8.26 -0.6 1.9e-13 Blood metabolite levels; TGCT cis rs3924048 0.574 rs11121924 chr1:12611629 A/G cg00291366 chr1:12616550 NA 0.32 4.87 0.4 3.34e-6 Optic cup area; TGCT cis rs10504229 0.679 rs11786328 chr8:58039269 A/G cg11062466 chr8:58055876 NA 0.46 4.89 0.4 3.07e-6 Developmental language disorder (linguistic errors); TGCT cis rs4808199 0.948 rs2023883 chr19:19405480 G/A cg03709012 chr19:19516395 GATAD2A 0.79 6.12 0.48 1.14e-8 Nonalcoholic fatty liver disease; TGCT cis rs1865760 0.613 rs9358894 chr6:25923315 C/T cg12310025 chr6:25882481 NA -0.51 -5.3 -0.43 5.11e-7 Height; TGCT cis rs7095607 0.704 rs1900013 chr10:69953929 A/G cg18986048 chr10:69913749 MYPN 0.58 6.79 0.52 4.14e-10 Lung function (FVC); TGCT cis rs7617773 0.817 rs3731497 chr3:48226553 T/G cg11946769 chr3:48343235 NME6 0.76 6.53 0.51 1.54e-9 Coronary artery disease; TGCT cis rs7267979 1.000 rs6076345 chr20:25381895 T/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg00475322 chr7:917719 C7orf20 -0.43 -5.79 -0.46 5.46e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs6671200 1.000 rs12755552 chr1:95685026 A/G cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs3806843 1.000 rs4404730 chr5:140162610 G/A cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg22963979 chr7:1858916 MAD1L1 -0.35 -5.49 -0.44 2.19e-7 Bipolar disorder and schizophrenia; TGCT cis rs7845219 0.544 rs9643352 chr8:95918288 C/T cg16049864 chr8:95962084 TP53INP1 -0.49 -5.36 -0.43 3.88e-7 Type 2 diabetes; TGCT cis rs4595586 0.545 rs11611625 chr12:39387207 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs1215050 0.605 rs1817220 chr4:98615196 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.605 rs202638 chr22:41855458 A/G cg13695892 chr22:41940480 POLR3H 0.92 9.22 0.64 9.72e-16 Vitiligo; TGCT cis rs3751972 0.681 rs4796147 chr17:26186288 A/G cg02948944 chr17:26242737 NA 0.38 5.37 0.43 3.8e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs4242434 0.927 rs11781149 chr8:22473158 C/T cg21658235 chr8:22456391 C8orf58 0.43 4.5 0.37 1.54e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2361718 0.500 rs12451697 chr17:78100690 T/A cg22255288 chr17:78854418 RPTOR -0.23 -4.48 -0.37 1.7e-5 Yeast infection; TGCT cis rs9811920 0.609 rs812657 chr3:99566329 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 6.82 0.52 3.63e-10 Axial length; TGCT cis rs9911578 0.757 rs8081906 chr17:56631907 A/T cg05425664 chr17:57184151 TRIM37 0.62 5.56 0.45 1.59e-7 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.875 rs864390 chr6:146315035 G/T cg05347473 chr6:146136440 FBXO30 0.49 4.69 0.39 7.23e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs651907 0.557 rs3094295 chr3:101401995 T/C cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs12134133 0.962 rs6673890 chr1:207415133 C/T cg02152968 chr1:207494213 CD55 0.6 4.65 0.39 8.43e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs9443645 0.901 rs12193319 chr6:79583437 C/A cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg11301795 chr4:187892539 NA -0.34 -5.25 -0.43 6.33e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7584330 0.554 rs74449293 chr2:238426458 G/A cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs17253792 0.822 rs80174205 chr14:56058694 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs36051895 0.623 rs62541541 chr9:5040817 G/C cg02405213 chr9:5042618 JAK2 -0.76 -10.28 -0.68 2.59e-18 Pediatric autoimmune diseases; TGCT cis rs9467603 1.000 rs9467606 chr6:25809218 A/G cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.904 rs755500 chr17:37409865 C/T cg15445000 chr17:37608096 MED1 0.31 4.58 0.38 1.11e-5 Glomerular filtration rate (creatinine); TGCT cis rs2075371 1.000 rs1868783 chr7:133975087 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.68e-9 Mean platelet volume; TGCT cis rs1801251 1.000 rs12474040 chr2:233615345 T/G cg08000102 chr2:233561755 GIGYF2 0.64 6.52 0.51 1.58e-9 Coronary artery disease; TGCT cis rs509477 0.887 rs595309 chr18:32562402 A/G cg23791764 chr18:32556832 MAPRE2 0.65 5.31 0.43 4.88e-7 Cerebrospinal fluid AB1-42 levels; TGCT cis rs6089829 0.926 rs1060489 chr20:61665921 C/T cg08564027 chr20:61660810 NA 0.37 6.64 0.51 8.85e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs6952808 0.792 rs4721184 chr7:1950784 T/C cg22963979 chr7:1858916 MAD1L1 -0.34 -5.24 -0.43 6.74e-7 Bipolar disorder and schizophrenia; TGCT cis rs74233809 1.000 rs11191575 chr10:104898337 C/T cg05855489 chr10:104503620 C10orf26 0.82 4.44 0.37 1.97e-5 Birth weight; TGCT cis rs9467711 0.538 rs13191445 chr6:26015489 G/A cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs59197085 0.636 rs60894155 chr7:128465755 G/A cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs9900497 0.604 rs12949049 chr17:19653310 A/G cg15323506 chr17:19619410 SLC47A2 0.21 5.1 0.42 1.26e-6 Response to paliperidone in schizophrenia (CGI-S score); TGCT cis rs739496 0.843 rs688812 chr12:111962581 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.16 0.42 9.31e-7 Platelet count; TGCT cis rs6598955 0.724 rs4659420 chr1:26614333 G/A cg04990556 chr1:26633338 UBXN11 -0.9 -11.73 -0.73 7.95e-22 Obesity-related traits; TGCT cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs11098499 0.866 rs6857892 chr4:120282696 G/T cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs10501293 0.662 rs4755686 chr11:42999785 A/C cg03447554 chr11:43094025 NA 0.44 6.49 0.5 1.81e-9 Cognitive performance; TGCT cis rs9818758 0.556 rs9813813 chr3:49207093 T/A cg00383909 chr3:49044727 WDR6 1.33 6.94 0.53 1.92e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2629540 0.781 rs11245362 chr10:126458649 T/C cg08799069 chr10:126477246 METTL10 -0.3 -4.5 -0.37 1.54e-5 Cocaine dependence; TGCT cis rs6121246 0.567 rs6060247 chr20:30190720 C/G cg13852791 chr20:30311386 BCL2L1 0.69 4.53 0.38 1.36e-5 Mean corpuscular hemoglobin; TGCT cis rs9611565 0.592 rs9611613 chr22:41961831 T/C cg06634786 chr22:41940651 POLR3H -0.88 -8.25 -0.6 1.98e-13 Vitiligo; TGCT cis rs4731207 0.596 rs1600739 chr7:124639606 A/G cg10503827 chr7:124401702 GPR37 0.21 4.61 0.38 1e-5 Cutaneous malignant melanoma; TGCT cis rs35306767 0.903 rs12254002 chr10:929133 A/G cg20503657 chr10:835505 NA -0.68 -9.25 -0.64 8.2e-16 Eosinophil percentage of granulocytes; TGCT cis rs7618915 0.851 rs34228726 chr3:52322797 A/G cg07507251 chr3:52567010 NT5DC2 0.46 6.11 0.48 1.18e-8 Bipolar disorder; TGCT cis rs11711311 0.747 rs7638378 chr3:113343630 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -5.88 -0.47 3.5e-8 IgG glycosylation; TGCT cis rs10504229 0.775 rs56082079 chr8:58163732 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs10992471 0.512 rs331379 chr9:95261104 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.51 -4.97 -0.41 2.13e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1429606 0.744 rs10050759 chr5:87246172 A/T cg09451457 chr5:87440246 NA 0.69 4.44 0.37 2e-5 Number of children (6+ vs. 0 or 1); TGCT cis rs1124769 0.502 rs28565448 chr15:51079970 C/T cg23028286 chr15:51614521 CYP19A1 0.19 4.47 0.37 1.75e-5 Cognitive performance; TGCT cis rs7772486 0.701 rs11155438 chr6:145950112 C/G cg13319975 chr6:146136371 FBXO30 -0.56 -5.06 -0.41 1.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs710216 0.619 rs11210771 chr1:43444560 T/C cg03128534 chr1:43423976 SLC2A1 -0.55 -4.63 -0.38 9.03e-6 Red cell distribution width; TGCT cis rs7208859 0.673 rs216409 chr17:28906269 C/T cg13385521 chr17:29058706 SUZ12P -0.71 -4.61 -0.38 9.83e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2439831 0.867 rs2255440 chr15:43830467 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.49 0.44 2.21e-7 Lung cancer in ever smokers; TGCT cis rs13108904 0.539 rs13145722 chr4:1338422 T/A cg00684032 chr4:1343700 KIAA1530 0.22 4.73 0.39 5.89e-6 Obesity-related traits; TGCT cis rs854765 0.624 rs12450799 chr17:17730201 T/C cg09796270 chr17:17721594 SREBF1 -0.25 -4.93 -0.4 2.63e-6 Total body bone mineral density; TGCT cis rs10465746 0.905 rs11163875 chr1:84429605 T/G cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs11190604 0.725 rs9420796 chr10:102323092 G/C cg23241863 chr10:102295624 HIF1AN 0.71 5.39 0.44 3.39e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1008375 0.872 rs2315552 chr4:17627294 A/G cg18681998 chr4:17616180 MED28 0.9 9.64 0.65 9.46e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs8072100 0.688 rs8075843 chr17:45442363 C/T cg08085267 chr17:45401833 C17orf57 -0.51 -5.61 -0.45 1.26e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs8177253 0.665 rs11921527 chr3:133441167 G/A cg11941060 chr3:133502564 NA -0.26 -5.39 -0.44 3.48e-7 Iron status biomarkers; TGCT cis rs4746818 0.793 rs2805914 chr10:70859291 A/G cg11621586 chr10:70884670 VPS26A 1.15 7.67 0.57 4.34e-12 Left atrial antero-posterior diameter; TGCT cis rs1129187 1.000 rs1129187 chr6:42932200 G/T cg27588902 chr6:42928151 GNMT -0.49 -5.93 -0.47 2.85e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1511802 0.666 rs62350519 chr4:187119701 G/A cg19358738 chr4:186734530 SORBS2 0.17 4.52 0.38 1.43e-5 Blood protein levels; TGCT cis rs9291683 0.530 rs11723970 chr4:9980462 T/C cg11266682 chr4:10021025 SLC2A9 0.62 8.63 0.61 2.51e-14 Bone mineral density; TGCT cis rs2204008 0.604 rs2320521 chr12:38253789 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.19e-11 Bladder cancer; TGCT cis rs13242816 1.000 rs17138708 chr7:116109062 T/G cg16553024 chr7:116138462 CAV2 -0.44 -4.53 -0.38 1.34e-5 P wave duration; TGCT cis rs919433 0.679 rs9967823 chr2:198531529 A/G cg00792783 chr2:198669748 PLCL1 0.54 5.02 0.41 1.77e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs2239547 0.603 rs7644973 chr3:53082937 C/T cg10802521 chr3:52805072 NEK4 -0.56 -5.12 -0.42 1.15e-6 Schizophrenia; TGCT cis rs6988636 1.000 rs28670850 chr8:124189125 A/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs11711311 1.000 rs9879760 chr3:113457948 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs7552404 0.656 rs11161792 chr1:76336746 C/T cg03433033 chr1:76189801 ACADM 0.6 5.75 0.46 6.43e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs707040 0.961 rs6760603 chr2:155234908 C/T cg18104148 chr2:154337490 NA 0.19 4.56 0.38 1.2e-5 Sudden cardiac arrest; TGCT cis rs651907 0.557 rs11924013 chr3:101366698 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.12 0.42 1.16e-6 Colorectal cancer; TGCT cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12541335 0.639 rs7003478 chr8:22201123 A/G cg18135555 chr8:22132992 PIWIL2 0.3 6.12 0.48 1.13e-8 Hypertriglyceridemia; TGCT cis rs71435601 0.689 rs17042000 chr2:21422928 C/T cg25035485 chr2:21266500 APOB -0.56 -4.76 -0.39 5.41e-6 Cholesterol, total; TGCT cis rs3733585 0.699 rs4276278 chr4:9948870 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.48 -0.5 1.95e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4642101 0.883 rs11718898 chr3:12848822 T/C cg05775895 chr3:12838266 CAND2 0.51 4.81 0.4 4.38e-6 QRS complex (12-leadsum); TGCT cis rs62103177 0.525 rs612913 chr18:77845882 A/G cg07235805 chr18:78004237 PARD6G -0.51 -4.98 -0.41 2.11e-6 Opioid sensitivity; TGCT trans rs4332037 0.754 rs62436669 chr7:1926636 G/A cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT trans rs17471911 0.708 rs11189937 chr10:100780715 A/G cg03484267 chr2:207988651 KLF7 0.53 6.79 0.52 4.24e-10 Neuroticism; TGCT cis rs2073300 1.000 rs6132628 chr20:23446734 G/A cg09953122 chr20:23471693 CST8 -0.64 -4.53 -0.38 1.37e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs112217694 1.000 rs17196160 chr4:104657842 T/C cg24090629 chr4:104641072 TACR3 -1.01 -4.96 -0.41 2.29e-6 Menarche (age at onset); TGCT cis rs288326 0.561 rs77460513 chr2:183819625 C/T cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Vitiligo; TGCT cis rs910316 0.789 rs175444 chr14:75601782 G/C cg08847533 chr14:75593920 NEK9 -0.85 -8.58 -0.61 3.22e-14 Height; TGCT cis rs2404602 0.735 rs4886493 chr15:76679026 A/G cg22467129 chr15:76604101 ETFA 0.46 4.67 0.39 7.85e-6 Blood metabolite levels; TGCT cis rs6087771 0.650 rs6060395 chr20:30219823 G/C cg13852791 chr20:30311386 BCL2L1 0.82 7.23 0.54 4.29e-11 Subcortical brain region volumes;Putamen volume; TGCT trans rs56011263 0.687 rs4690187 chr4:703813 C/T cg12575136 chr18:32820987 ZNF397 0.77 9.37 0.64 4.3e-16 White blood cell count; TGCT cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs9500256 0.655 rs12191043 chr6:58346483 C/T cg16251399 chr6:58287822 GUSBL2 0.56 4.63 0.38 9.04e-6 Eosinophilic esophagitis (pediatric); TGCT cis rs11118844 0.744 rs11118857 chr1:221952209 C/T cg04222084 chr1:221915650 DUSP10 -0.78 -4.66 -0.39 8.03e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs17376456 0.877 rs12716457 chr5:93397627 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs4561483 0.549 rs6498251 chr16:11952290 A/G cg08843971 chr16:11963173 GSPT1 0.25 4.55 0.38 1.24e-5 Testicular germ cell tumor; TGCT cis rs2243480 1.000 rs316313 chr7:65593548 G/A cg07424592 chr7:64974309 NA 1.26 7.79 0.57 2.25e-12 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs7698771 chr4:98986479 T/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3741404 0.791 rs2282491 chr11:63918373 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.88 9.92 0.67 2.01e-17 Platelet count; TGCT cis rs875971 1.000 rs6957199 chr7:65978519 T/C cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs7267979 0.966 rs3002698 chr20:25303379 C/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13242816 1.000 rs2402078 chr7:116128648 A/C cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs6840360 0.593 rs10022023 chr4:152560731 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs910316 1.000 rs3742778 chr14:75538217 A/C cg23033748 chr14:75592666 NEK9 -0.28 -4.64 -0.38 8.62e-6 Height; TGCT trans rs1908814 0.516 rs13275143 chr8:11796990 T/A cg15556689 chr8:8085844 FLJ10661 0.74 6.77 0.52 4.66e-10 Neuroticism; TGCT cis rs1857353 1.000 rs1858630 chr1:75890640 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs1448094 0.511 rs58742237 chr12:86166444 C/T cg02569458 chr12:86230093 RASSF9 0.38 4.5 0.37 1.57e-5 Major depressive disorder; TGCT cis rs362272 0.545 rs2749785 chr4:3325179 G/C cg18352616 chr4:3374830 RGS12 0.23 4.5 0.37 1.57e-5 Serum sulfate level; TGCT cis rs7666738 0.830 rs35865860 chr4:98968822 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7710178 0.525 rs32073 chr5:156112063 A/G cg19020398 chr5:156886415 NIPAL4 0.3 4.49 0.37 1.61e-5 Airway responsiveness in chronic obstructive pulmonary disease; TGCT cis rs2463822 0.748 rs2513053 chr11:62109473 T/A cg06239285 chr11:62104954 ASRGL1 0.9 6.34 0.49 3.87e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6867032 0.834 rs4526149 chr5:1990166 G/A cg26168224 chr5:2018326 NA -0.33 -5.16 -0.42 9.67e-7 Gut microbiome composition (winter); TGCT cis rs9814567 0.964 rs3856729 chr3:134200925 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.97 -9.24 -0.64 8.89e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs896854 0.654 rs28716845 chr8:95974485 A/G cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs76878669 0.561 rs7940980 chr11:66172910 C/T cg18002602 chr11:66138449 SLC29A2 -0.53 -6.38 -0.5 3.25e-9 Educational attainment (years of education); TGCT trans rs57221529 0.766 rs12519469 chr5:581772 A/G cg25482853 chr8:67687455 SGK3 1.2 11.56 0.72 2.06e-21 Lung disease severity in cystic fibrosis; TGCT cis rs10089 0.953 rs758180 chr5:127354423 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.73 6.75 0.52 5e-10 Ileal carcinoids; TGCT cis rs4711350 0.954 rs11751943 chr6:33729718 G/C cg00334056 chr6:33755658 LEMD2 -0.31 -4.83 -0.4 3.88e-6 Schizophrenia; TGCT cis rs6429082 0.764 rs291377 chr1:235695186 C/T cg26050004 chr1:235667680 B3GALNT2 -0.63 -5.58 -0.45 1.43e-7 Adiposity; TGCT cis rs2073300 1.000 rs6137961 chr20:23443102 G/T cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7582180 0.629 rs4850926 chr2:100954117 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs1158570 0.804 rs2185366 chr8:131342722 T/C cg16277922 chr8:131349729 ASAP1 -0.43 -6.18 -0.49 8.38e-9 Platelet count; TGCT trans rs3780486 0.846 rs3824458 chr9:33144809 C/T cg04842962 chr6:43655489 MRPS18A 1.2 14.72 0.8 5.46e-29 IgG glycosylation; TGCT cis rs7937682 0.575 rs7950926 chr11:111776437 G/C cg09085632 chr11:111637200 PPP2R1B 0.94 9.24 0.64 8.92e-16 Primary sclerosing cholangitis; TGCT cis rs10493773 1.000 rs55654440 chr1:86176158 G/C cg17807903 chr1:86174739 ZNHIT6 -0.38 -4.61 -0.38 9.67e-6 Urate levels in overweight individuals; TGCT cis rs9914544 0.966 rs7210746 chr17:18798593 T/C cg26378065 chr17:18585709 ZNF286B 0.52 4.73 0.39 5.94e-6 Educational attainment (years of education); TGCT cis rs6701037 0.681 rs1057239 chr1:175130204 G/A cg00321850 chr1:175162397 KIAA0040 -0.4 -5.29 -0.43 5.37e-7 Alcohol dependence; TGCT cis rs1371867 0.817 rs1660314 chr8:101332953 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs3806843 1.000 rs10477034 chr5:140169730 A/G cg19875535 chr5:140030758 IK 0.37 6.39 0.5 3.11e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs11792861 0.855 rs116127510 chr9:111868344 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.48 0.37 1.66e-5 Menarche (age at onset); TGCT cis rs6909279 0.933 rs6557149 chr6:151876413 C/T cg14416726 chr6:151773293 C6orf211;RMND1 0.51 4.47 0.37 1.75e-5 Bone mineral density; TGCT cis rs9896933 0.832 rs75552659 chr17:80804630 G/A cg20578329 chr17:80767326 TBCD -0.35 -4.99 -0.41 1.99e-6 Bone mineral accretion in asthma (oral corticosteroid dose interaction); TGCT cis rs250677 0.522 rs998304 chr5:148382365 C/A cg18129178 chr5:148520854 ABLIM3 -0.36 -4.69 -0.39 7.23e-6 Breast cancer; TGCT cis rs6089584 0.606 rs6089599 chr20:60576992 A/G cg06108461 chr20:60628389 TAF4 0.4 4.92 0.4 2.74e-6 Body mass index; TGCT trans rs524675 0.525 rs517536 chr4:13959691 A/T cg02315626 chr17:27188560 MIR451;MIR144 0.4 6.75 0.52 5.03e-10 Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals; TGCT cis rs9467773 0.596 rs2451750 chr6:26646579 A/T cg05738196 chr6:26577821 NA 0.88 10.63 0.69 3.68e-19 Intelligence (multi-trait analysis); TGCT cis rs7681440 0.904 rs28750169 chr4:90774303 A/G cg14346243 chr4:90757452 SNCA -0.57 -5.5 -0.44 2.04e-7 Dementia with Lewy bodies; TGCT cis rs250677 0.958 rs36067 chr5:148417553 T/G cg18129178 chr5:148520854 ABLIM3 -0.4 -5.63 -0.45 1.17e-7 Breast cancer; TGCT cis rs7216064 0.953 rs4790905 chr17:65863350 C/A cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6964587 1.000 rs6956596 chr7:91750107 T/G cg22709100 chr7:91322751 NA 0.28 4.55 0.38 1.25e-5 Breast cancer; TGCT cis rs11167764 0.895 rs9324865 chr5:141488792 T/C cg23435118 chr5:141488016 NDFIP1 -0.28 -4.84 -0.4 3.83e-6 Crohn's disease; TGCT cis rs4665809 1.000 rs1371553 chr2:26262948 G/A cg22920501 chr2:26401640 FAM59B -0.72 -6.22 -0.49 7.14e-9 Gut microbiome composition (summer); TGCT cis rs8177253 0.828 rs8177259 chr3:133480388 T/C cg08439880 chr3:133502540 NA -0.31 -5.91 -0.47 3.1e-8 Iron status biomarkers; TGCT cis rs8180040 0.966 rs4858868 chr3:47455086 G/A cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs1008375 1.000 rs4698198 chr4:17656536 G/A cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3540 0.533 rs11633692 chr15:91056043 G/A cg22089800 chr15:90895588 ZNF774 -0.76 -7.96 -0.58 9.11e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7914558 0.966 rs7908280 chr10:104816947 C/G cg04362960 chr10:104952993 NT5C2 0.61 5.48 0.44 2.28e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg06481639 chr22:41940642 POLR3H -0.69 -6.02 -0.48 1.83e-8 Vitiligo; TGCT trans rs9388451 0.839 rs9401845 chr6:126104118 A/G cg05039488 chr6:79577232 IRAK1BP1 -0.72 -8.04 -0.59 6.03e-13 Brugada syndrome; TGCT cis rs11098499 0.863 rs1010739 chr4:120463471 C/T cg24670566 chr4:120433619 PDE5A 0.24 4.45 0.37 1.87e-5 Corneal astigmatism; TGCT cis rs1775715 0.707 rs2808079 chr10:32167385 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs10256972 0.591 rs6968988 chr7:1169619 A/G cg04025307 chr7:1156635 C7orf50 0.23 5.57 0.45 1.47e-7 Longevity;Endometriosis; TGCT cis rs9388451 0.513 rs1268069 chr6:126039994 A/C cg05901451 chr6:126070800 HEY2 -0.87 -9.95 -0.67 1.7e-17 Brugada syndrome; TGCT cis rs11031096 0.655 rs12275560 chr11:4211564 T/C cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs4819052 0.851 rs2838858 chr21:46681093 T/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.7 0.39 6.83e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1107366 0.513 rs35078897 chr3:125973767 T/C cg01346077 chr3:125931526 NA 0.32 5.3 0.43 5.03e-7 Metabolite levels; TGCT cis rs1799949 1.000 rs12944430 chr17:41330820 C/G cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs2204008 0.774 rs10400552 chr12:38393577 C/G cg26384229 chr12:38710491 ALG10B 0.83 7.39 0.55 1.92e-11 Bladder cancer; TGCT cis rs42648 0.902 rs17874789 chr7:90001160 A/T cg25739043 chr7:89950458 NA 0.65 6.23 0.49 6.69e-9 Homocysteine levels; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.44 4.98 0.41 2.05e-6 Lymphocyte counts; TGCT cis rs9611565 1.000 rs9611565 chr22:41767486 T/C cg06634786 chr22:41940651 POLR3H -0.66 -6.16 -0.48 9.24e-9 Vitiligo; TGCT cis rs1903068 0.853 rs17773240 chr4:55999781 T/C cg01777861 chr4:56023843 NA 0.54 6.38 0.5 3.2e-9 Endometriosis; TGCT cis rs597539 0.652 rs544370 chr11:68653232 C/T cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.62e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4788570 0.727 rs7204118 chr16:71833658 G/C cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs933688 1.000 rs7720132 chr5:90745105 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.47 0.61 6.09e-14 Smoking behavior; TGCT cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg03264133 chr6:25882463 NA -0.73 -6.87 -0.53 2.74e-10 Intelligence (multi-trait analysis); TGCT cis rs10838634 1.000 rs2867206 chr11:46854977 C/T cg18332754 chr11:46939436 LRP4 0.9 4.58 0.38 1.11e-5 Schizophrenia; TGCT cis rs10465746 0.935 rs1871925 chr1:84464468 C/G cg10977910 chr1:84465055 TTLL7 0.63 6.24 0.49 6.38e-9 Obesity-related traits; TGCT cis rs11997175 0.549 rs4357253 chr8:33652458 G/A ch.8.33884649F chr8:33765107 NA 0.28 4.53 0.38 1.35e-5 Body mass index; TGCT cis rs7959452 0.640 rs4761154 chr12:69705362 A/G cg14784868 chr12:69753453 YEATS4 -0.68 -6.95 -0.53 1.81e-10 Blood protein levels; TGCT trans rs1814175 0.645 rs10742953 chr11:49807491 C/G cg11707556 chr5:10655725 ANKRD33B 0.45 11.15 0.71 2.03e-20 Height; TGCT cis rs1949733 0.656 rs2631762 chr4:8423122 A/T cg11789530 chr4:8429930 ACOX3 0.54 4.99 0.41 1.98e-6 Response to antineoplastic agents; TGCT cis rs4730250 0.655 rs75243311 chr7:106890791 C/T cg02696742 chr7:106810147 HBP1 -0.66 -5.51 -0.44 1.94e-7 Osteoarthritis; TGCT cis rs2227564 0.620 rs7098573 chr10:75580014 G/A cg23231163 chr10:75533350 FUT11 -0.28 -4.46 -0.37 1.82e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs17767294 0.522 rs41270589 chr6:28403440 G/A cg08851530 chr6:28072375 NA 1.57 7.31 0.55 2.88e-11 Parkinson's disease; TGCT cis rs7819412 0.775 rs2001329 chr8:10986859 C/T cg21775007 chr8:11205619 TDH -0.55 -5.22 -0.42 7.46e-7 Triglycerides; TGCT cis rs1061377 1.000 rs9990755 chr4:39121439 G/T cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs523522 0.962 rs10744752 chr12:120900554 T/G cg12219531 chr12:120966889 COQ5 0.83 7.3 0.55 2.97e-11 High light scatter reticulocyte count; TGCT cis rs80282103 0.618 rs1079390 chr10:1161653 C/A cg08668510 chr10:1095578 IDI1 1.06 5.03 0.41 1.7e-6 Glomerular filtration rate (creatinine); TGCT cis rs12048904 0.930 rs11166529 chr1:101333733 C/T cg16556008 chr1:101360663 SLC30A7;EXTL2 0.55 5.17 0.42 9.05e-7 Multiple sclerosis; TGCT cis rs2153535 0.601 rs1737581 chr6:8539138 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg12310025 chr6:25882481 NA -0.74 -6.75 -0.52 4.98e-10 Intelligence (multi-trait analysis); TGCT cis rs7698623 0.850 rs4693891 chr4:88787834 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs12497850 0.931 rs28642807 chr3:48926816 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs2439831 0.867 rs2242068 chr15:43699304 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.32 0.43 4.75e-7 Lung cancer in ever smokers; TGCT cis rs9660180 0.837 rs915292 chr1:1792157 A/C cg03396347 chr1:1875803 NA -0.36 -6.46 -0.5 2.14e-9 Body mass index; TGCT cis rs11711311 1.000 rs9827682 chr3:113450251 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.73 -6.83 -0.52 3.45e-10 IgG glycosylation; TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs6840360 0.615 rs6535816 chr4:152614264 T/C cg17479576 chr4:152424074 FAM160A1 -0.52 -5.09 -0.42 1.3e-6 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.962 rs6122350 chr20:61664617 A/G cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs10744422 1.000 rs921808 chr12:123323135 A/G cg25930673 chr12:123319894 HIP1R 0.85 5.01 0.41 1.86e-6 Schizophrenia; TGCT cis rs2506155 0.752 rs2300947 chr10:33517262 C/T cg25928881 chr10:32632685 EPC1 0.31 4.65 0.39 8.31e-6 Migraine; TGCT cis rs5769707 0.681 rs135879 chr22:50018651 C/T cg05373962 chr22:49881684 NA -0.3 -5.25 -0.43 6.29e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6940638 0.956 rs12199218 chr6:27025281 T/C cg26531700 chr6:26746687 NA -0.59 -4.47 -0.37 1.77e-5 Intelligence (multi-trait analysis); TGCT cis rs12765878 0.729 rs12573103 chr10:105639241 A/G cg11005552 chr10:105648138 OBFC1 0.4 6.77 0.52 4.65e-10 Coronary artery disease; TGCT cis rs6951245 0.554 rs11544331 chr7:1131411 C/T cg03188948 chr7:1209495 NA 0.52 5.4 0.44 3.29e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs67478160 0.634 rs2144079 chr14:104258884 C/T cg26031613 chr14:104095156 KLC1 -0.62 -6.19 -0.49 8.13e-9 Schizophrenia; TGCT cis rs9303401 0.659 rs34382037 chr17:56643550 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs2688608 0.967 rs9971038 chr10:75661149 C/T cg19442545 chr10:75533431 FUT11 -0.3 -4.83 -0.4 3.88e-6 Inflammatory bowel disease; TGCT cis rs9325144 0.577 rs12314639 chr12:39119869 T/C cg13010199 chr12:38710504 ALG10B -0.53 -4.72 -0.39 6.22e-6 Morning vs. evening chronotype; TGCT cis rs939658 0.776 rs35382567 chr15:79440897 C/T cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs9916302 0.706 rs801427 chr17:37436711 A/G cg07936489 chr17:37558343 FBXL20 -0.84 -6.23 -0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs7043114 0.525 rs10820964 chr9:95041636 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.57 -0.45 1.53e-7 Height; TGCT cis rs7914558 1.000 rs10748838 chr10:104943986 T/A cg04362960 chr10:104952993 NT5C2 0.61 5.47 0.44 2.42e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg11890956 chr21:40555474 PSMG1 1.14 12.22 0.74 4.93e-23 Cognitive function; TGCT cis rs739496 0.579 rs11066095 chr12:112377537 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs2013441 1.000 rs2013576 chr17:20167692 G/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs10488031 0.850 rs35721463 chr7:37112015 G/A cg06458904 chr7:36312573 EEPD1 0.54 4.63 0.38 9.22e-6 QT interval; TGCT cis rs79349575 0.783 rs62078370 chr17:47026836 G/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs4642101 0.686 rs13085726 chr3:12832672 A/C cg05775895 chr3:12838266 CAND2 0.91 11.07 0.7 3.17e-20 QRS complex (12-leadsum); TGCT cis rs2836950 0.545 rs2836952 chr21:40616651 G/C cg11890956 chr21:40555474 PSMG1 -0.69 -6.74 -0.52 5.41e-10 Menarche (age at onset); TGCT cis rs9527 0.569 rs78193706 chr10:104780564 T/C cg04362960 chr10:104952993 NT5C2 0.65 5.54 0.45 1.73e-7 Arsenic metabolism; TGCT cis rs7833790 0.632 rs6473308 chr8:82707708 G/A cg06027949 chr8:82754900 SNX16 -0.65 -4.93 -0.41 2.53e-6 Diastolic blood pressure; TGCT cis rs12681287 0.605 rs13262672 chr8:87355812 T/C cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs11209185 0.509 rs1938424 chr1:68431722 A/G cg22082780 chr1:68452167 NA -0.31 -4.66 -0.39 8.01e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs4843185 0.669 rs889502 chr16:85716832 A/G cg02644593 chr16:85391138 NA 0.22 5.0 0.41 1.92e-6 Platelet distribution width; TGCT cis rs12908161 0.920 rs35738019 chr15:85280210 T/C cg11189052 chr15:85197271 WDR73 0.7 5.71 0.46 7.73e-8 Schizophrenia; TGCT cis rs2762353 0.845 rs35720558 chr6:25784800 A/C cg03517284 chr6:25882590 NA 0.5 5.23 0.42 7.13e-7 Blood metabolite levels; TGCT cis rs72634258 0.520 rs4908485 chr1:7907984 A/G cg26816564 chr1:7831052 VAMP3 0.86 6.29 0.49 5.01e-9 Inflammatory bowel disease; TGCT cis rs6728302 0.557 rs7600132 chr2:233248198 C/A cg06555452 chr2:233241558 NA 0.37 5.16 0.42 9.6e-7 Height; TGCT cis rs427394 0.582 rs4701751 chr5:6704137 C/T cg10857441 chr5:6722123 POLS -0.29 -6.21 -0.49 7.15e-9 Menopause (age at onset); TGCT cis rs4409675 0.576 rs2078328 chr1:28224976 A/G cg23691781 chr1:28212827 C1orf38 0.25 5.15 0.42 1.01e-6 Corneal astigmatism; TGCT cis rs12541335 0.639 rs68063696 chr8:22153236 A/G cg18135555 chr8:22132992 PIWIL2 0.29 5.62 0.45 1.21e-7 Hypertriglyceridemia; TGCT cis rs10791097 0.765 rs10894269 chr11:130722789 C/T cg05962950 chr11:130786565 SNX19 0.83 9.85 0.66 2.99e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2562456 0.917 rs11085463 chr19:21751302 G/T cg01304269 chr19:21688519 ZNF429 0.55 4.56 0.38 1.2e-5 Pain; TGCT cis rs9894429 0.966 rs6565604 chr17:79589242 G/A cg18240062 chr17:79603768 NPLOC4 0.67 6.85 0.52 3.11e-10 Eye color traits; TGCT cis rs12681287 0.604 rs13279589 chr8:87477723 C/T cg19078186 chr8:87526527 CPNE3 -0.36 -4.45 -0.37 1.86e-5 Caudate activity during reward; TGCT cis rs9916302 0.904 rs585961 chr17:37444036 G/A cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs1467026 0.606 rs9814180 chr3:12818386 A/G cg05775895 chr3:12838266 CAND2 0.78 7.74 0.57 3.04e-12 P wave duration; TGCT cis rs2404602 0.647 rs4886840 chr15:77179002 A/G cg23625390 chr15:77176239 SCAPER -0.39 -5.15 -0.42 9.85e-7 Blood metabolite levels; TGCT cis rs10779751 1.000 rs11121706 chr1:11302065 C/T cg08854313 chr1:11322531 MTOR 0.98 10.78 0.7 1.5700000000000001e-19 Body mass index; TGCT cis rs7267979 0.844 rs6115188 chr20:25432170 G/T cg03522245 chr20:25566470 NINL 0.55 5.54 0.45 1.7e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2836974 0.899 rs34433511 chr21:40618883 A/C cg11644478 chr21:40555479 PSMG1 1.0 10.69 0.69 2.7e-19 Cognitive function; TGCT cis rs2797160 1.000 rs1935772 chr6:125994708 T/C cg05901451 chr6:126070800 HEY2 -0.74 -6.57 -0.51 1.23e-9 Endometrial cancer; TGCT cis rs8067545 1.000 rs2108980 chr17:19920518 G/A cg13482628 chr17:19912719 NA 0.54 4.74 0.39 5.86e-6 Schizophrenia; TGCT cis rs12049351 0.774 rs10916495 chr1:229635521 A/G cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs986417 1.000 rs11845369 chr14:60944959 A/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs6570726 0.791 rs365869 chr6:145884751 C/T cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1843834 0.688 rs2396149 chr2:225601985 G/A cg22455342 chr2:225449267 CUL3 0.65 6.26 0.49 5.64e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs1372520 0.627 rs2737025 chr4:90719192 A/G cg20003494 chr4:90757398 SNCA -0.66 -5.21 -0.42 7.59e-7 Neuroticism; TGCT cis rs1903068 0.962 rs17773813 chr4:56008969 G/A cg16572876 chr4:56024045 NA 0.44 5.1 0.42 1.23e-6 Endometriosis; TGCT cis rs12908161 1.000 rs35630683 chr15:85349231 T/C cg17173187 chr15:85201210 NMB 0.57 6.39 0.5 3.07e-9 Schizophrenia; TGCT cis rs2688608 0.967 rs2688609 chr10:75658181 A/G cg23231163 chr10:75533350 FUT11 0.26 4.49 0.37 1.64e-5 Inflammatory bowel disease; TGCT cis rs1997103 1.000 rs10279035 chr7:55412055 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg10819733 chr22:24237672 NA -0.3 -5.02 -0.41 1.78e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9581857 0.579 rs77187836 chr13:27998646 C/A cg22138327 chr13:27999177 GTF3A 0.78 5.58 0.45 1.43e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs1385374 0.858 rs12305142 chr12:129277490 C/T cg09035930 chr12:129282057 SLC15A4 -0.5 -4.77 -0.39 4.99e-6 Systemic lupus erythematosus; TGCT cis rs11924390 0.800 rs5030059 chr3:186452455 C/G cg12454167 chr3:186435060 KNG1 0.44 6.91 0.53 2.24e-10 Adiponectin levels; TGCT cis rs11098499 0.569 rs10023641 chr4:120258410 C/G cg09307838 chr4:120376055 NA 0.55 5.33 0.43 4.45e-7 Corneal astigmatism; TGCT cis rs5769765 0.955 rs8138687 chr22:50291869 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.91 0.47 3.12e-8 Schizophrenia; TGCT cis rs826838 0.874 rs11183816 chr12:38834656 T/G cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs36051895 0.632 rs10974984 chr9:5150427 T/C cg02405213 chr9:5042618 JAK2 -0.73 -9.46 -0.65 2.54e-16 Pediatric autoimmune diseases; TGCT cis rs7267979 0.844 rs6050477 chr20:25221547 C/T cg16686733 chr20:25566563 NINL -0.55 -5.57 -0.45 1.47e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs801193 0.636 rs2659895 chr7:66196471 C/A cg18876405 chr7:65276391 NA 0.33 4.86 0.4 3.46e-6 Aortic root size; TGCT cis rs6815814 0.950 rs5743560 chr4:38806200 G/T cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs904251 0.600 rs9380673 chr6:37415125 T/C cg01843034 chr6:37503916 NA -0.46 -5.89 -0.47 3.44e-8 Cognitive performance; TGCT cis rs12477438 0.520 rs6743355 chr2:99732360 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs769267 0.930 rs4808203 chr19:19568659 A/G cg03709012 chr19:19516395 GATAD2A 0.77 6.28 0.49 5.18e-9 Tonsillectomy; TGCT cis rs9393777 0.513 rs9379907 chr6:26654318 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs6921919 0.583 rs1054372 chr6:28336742 G/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.37 -0.43 3.8e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11779988 0.545 rs398806 chr8:17786226 T/C cg01800426 chr8:17659068 MTUS1 -0.7 -5.46 -0.44 2.5e-7 Breast cancer; TGCT cis rs589448 0.872 rs315111 chr12:69784695 G/A cg20891283 chr12:69753455 YEATS4 0.91 10.46 0.68 9.81e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg12751644 chr20:60527061 NA -0.39 -4.59 -0.38 1.07e-5 Body mass index; TGCT trans rs208520 1.000 rs12194996 chr6:66973366 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.82 7.48 0.56 1.21e-11 Exhaled nitric oxide output; TGCT cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg21433313 chr16:3507492 NAT15 0.38 4.92 0.4 2.68e-6 Tuberculosis; TGCT cis rs35146811 0.586 rs12666107 chr7:99778019 G/C cg13334819 chr7:99746414 C7orf59 -0.82 -6.99 -0.53 1.54e-10 Coronary artery disease; TGCT cis rs9733 0.596 rs12063547 chr1:150674053 G/T cg09365446 chr1:150670422 GOLPH3L -0.29 -4.52 -0.38 1.44e-5 Tonsillectomy; TGCT cis rs12477438 0.798 rs1453561 chr2:99613924 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.31 -0.6 1.43e-13 Chronic sinus infection; TGCT cis rs11676348 0.818 rs1126579 chr2:219000734 T/C cg00012203 chr2:219082015 ARPC2 -0.51 -4.86 -0.4 3.53e-6 Ulcerative colitis; TGCT cis rs4820539 0.966 rs5751590 chr22:23486830 A/C cg21100191 chr22:23484243 RTDR1 0.92 10.9 0.7 8.12e-20 Bone mineral density; TGCT cis rs10423674 0.526 rs757317 chr19:18819984 C/T cg14292368 chr19:18793705 CRTC1 -0.53 -4.89 -0.4 3.1e-6 Menarche (age at onset); TGCT cis rs28595532 0.920 rs114223775 chr4:119775091 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs904251 1.000 rs12212090 chr6:37431808 A/G cg01843034 chr6:37503916 NA -0.46 -5.44 -0.44 2.72e-7 Cognitive performance; TGCT cis rs11190604 1.000 rs2273695 chr10:102259568 A/G cg16342193 chr10:102329863 NA -0.37 -5.05 -0.41 1.55e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7582180 0.764 rs920269 chr2:100918363 G/A cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.45e-6 Intelligence (multi-trait analysis); TGCT cis rs6558530 0.965 rs730379 chr8:1708093 A/C cg09410841 chr8:1729607 CLN8 0.91 10.31 0.68 2.23e-18 Systolic blood pressure; TGCT cis rs7043114 0.525 rs10283572 chr9:95133074 G/A cg14631576 chr9:95140430 CENPP -0.28 -4.69 -0.39 6.98e-6 Height; TGCT cis rs56011263 0.687 rs4690188 chr4:703930 G/C cg17689763 chr4:710664 PCGF3 -0.25 -7.28 -0.55 3.38e-11 White blood cell count; TGCT cis rs7095607 1.000 rs4746740 chr10:69960999 C/T cg18986048 chr10:69913749 MYPN 0.45 4.86 0.4 3.52e-6 Lung function (FVC); TGCT cis rs2032447 0.839 rs9356995 chr6:25996673 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.9 9.57 0.65 1.42e-16 Intelligence (multi-trait analysis); TGCT cis rs1059312 1.000 rs7135987 chr12:129280117 G/A cg09035930 chr12:129282057 SLC15A4 0.59 11.76 0.73 6.45e-22 Systemic lupus erythematosus; TGCT cis rs9906944 0.707 rs1523136 chr17:47144532 A/G cg20966754 chr17:47091339 IGF2BP1 -0.47 -5.33 -0.43 4.46e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs10484885 0.824 rs72919982 chr6:90532600 C/G cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs12681287 0.511 rs7839601 chr8:87503839 G/C cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs7582180 0.764 rs12712075 chr2:100924129 T/C cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs9330316 0.506 rs1434167 chr2:110396324 A/G cg03552103 chr2:110373002 SEPT10;ANKRD57 -0.42 -4.75 -0.39 5.55e-6 Schizophrenia; TGCT cis rs9467603 0.566 rs10214468 chr6:25789390 T/A cg03517284 chr6:25882590 NA -0.66 -4.5 -0.37 1.53e-5 Intelligence (multi-trait analysis); TGCT cis rs655029 0.837 rs647316 chr2:31464829 A/G cg14018959 chr2:31480232 EHD3 -0.38 -5.09 -0.42 1.3e-6 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs4654899 0.733 rs10442633 chr1:21265097 C/T cg01072550 chr1:21505969 NA -0.56 -9.04 -0.63 2.64e-15 Superior frontal gyrus grey matter volume; TGCT trans rs1814175 0.715 rs11040586 chr11:49858432 T/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs10779751 0.922 rs2295080 chr1:11322628 G/T cg08854313 chr1:11322531 MTOR 0.93 10.45 0.68 1e-18 Body mass index; TGCT cis rs13242816 1.000 rs55803834 chr7:116103141 C/T cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs5769707 0.749 rs7286706 chr22:50058346 G/C cg05373962 chr22:49881684 NA -0.3 -5.98 -0.47 2.18e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7666738 0.612 rs6830172 chr4:99093947 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.07 0.41 1.39e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8077577 1.000 rs2015336 chr17:18073610 A/G cg09161412 chr17:18057145 MYO15A -0.63 -5.02 -0.41 1.74e-6 Obesity-related traits; TGCT cis rs7208859 0.623 rs55724095 chr17:29153058 A/G cg14008862 chr17:28927542 LRRC37B2 0.75 5.06 0.41 1.5e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7555006 0.671 rs11580026 chr1:51476003 A/T cg10511332 chr1:51166032 FAF1 0.36 4.58 0.38 1.1e-5 Headache; TGCT cis rs6570726 0.935 rs442254 chr6:145849118 T/C cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs8073060 0.586 rs2011897 chr17:34054408 A/T cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs539096 0.624 rs603542 chr1:44079411 T/C cg12908607 chr1:44402522 ARTN -0.44 -4.86 -0.4 3.55e-6 Intelligence (multi-trait analysis); TGCT cis rs7223966 0.921 rs67018565 chr17:61928055 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2204008 0.818 rs1589389 chr12:38416041 G/A cg26384229 chr12:38710491 ALG10B -0.79 -7.26 -0.55 3.78e-11 Bladder cancer; TGCT cis rs4819052 0.851 rs2838857 chr21:46681000 A/G cg06618935 chr21:46677482 NA -0.36 -5.38 -0.44 3.57e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6570726 0.643 rs9403735 chr6:145936591 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.69 0.66 7.3e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10824037 0.673 rs11000789 chr10:75595226 T/G cg07699608 chr10:75541558 CHCHD1 0.73 5.15 0.42 9.93e-7 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs13256369 0.802 rs11249888 chr8:8564934 T/C cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs916888 0.773 rs199451 chr17:44801784 G/A cg16520312 chr17:43971471 MAPT;LOC100128977 -0.62 -5.32 -0.43 4.67e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7208859 0.573 rs56031503 chr17:29075665 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg15462221 chr8:8086144 FLJ10661 0.56 5.54 0.45 1.74e-7 Neuroticism; TGCT cis rs9911578 0.967 rs12603238 chr17:57130785 C/T cg12560992 chr17:57184187 TRIM37 -0.79 -9.73 -0.66 5.74e-17 Intelligence (multi-trait analysis); TGCT cis rs9486719 0.895 rs12195315 chr6:96905711 T/G cg06623918 chr6:96969491 KIAA0776 -0.98 -8.77 -0.62 1.15e-14 Migraine;Coronary artery disease; TGCT cis rs3733585 0.605 rs56178126 chr4:10123581 C/T cg00071950 chr4:10020882 SLC2A9 -0.51 -5.3 -0.43 5.07e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3733585 0.673 rs4407505 chr4:9953367 T/G cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3784262 0.507 rs1992231 chr15:58190937 A/G cg12031962 chr15:58353849 ALDH1A2 0.48 6.48 0.5 1.94e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7086627 0.515 rs10887905 chr10:82210855 A/T cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs77972916 0.505 rs6719754 chr2:43526386 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -5.66 -0.45 9.81e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs7824557 0.564 rs34964435 chr8:11230206 G/T cg21775007 chr8:11205619 TDH -0.61 -5.84 -0.46 4.36e-8 Retinal vascular caliber; TGCT cis rs7582180 0.629 rs11686880 chr2:100956229 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.69 0.39 7.19e-6 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.877 rs3817999 chr22:41747717 A/G cg03806693 chr22:41940476 POLR3H 1.04 11.79 0.73 5.71e-22 Vitiligo; TGCT cis rs8072100 0.748 rs9912592 chr17:45556945 G/A cg08085267 chr17:45401833 C17orf57 -0.48 -5.24 -0.43 6.8e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2760061 0.598 rs2796056 chr1:228122901 G/A cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs7666738 0.830 rs6840766 chr4:99016260 C/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6912958 0.781 rs9444522 chr6:88309705 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.57 -0.38 1.16e-5 Monocyte percentage of white cells; TGCT cis rs7267979 1.000 rs6083862 chr20:25411086 A/T cg03522245 chr20:25566470 NINL -0.61 -6.65 -0.51 8.4e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2820315 0.867 rs2820323 chr1:201883160 G/A cg12730843 chr1:201915899 LMOD1 -0.26 -4.84 -0.4 3.8e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs736801 0.521 rs2070729 chr5:131819921 G/T cg02551604 chr5:131831745 NA -0.77 -8.86 -0.62 7.04e-15 Breast cancer;Mosquito bite size; TGCT cis rs7432375 0.901 rs4408829 chr3:136404683 C/T cg12473912 chr3:136751656 NA -0.36 -5.06 -0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT trans rs7613875 0.600 rs7061 chr3:50114515 C/T cg21659725 chr3:3221576 CRBN -0.65 -7.16 -0.54 6.39e-11 Body mass index; TGCT cis rs910316 0.967 rs12890371 chr14:75593839 T/C cg11812906 chr14:75593930 NEK9 0.74 7.37 0.55 2.12e-11 Height; TGCT cis rs926938 0.527 rs360665 chr1:115478503 A/T cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs7582180 0.564 rs2309795 chr2:100954290 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.95 -0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT trans rs10203711 1.000 rs10203711 chr2:239553368 C/T cg16021909 chr1:248021091 TRIM58 -0.68 -6.93 -0.53 2.04e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 1.000 rs10032326 chr4:17630717 A/T cg10189774 chr4:17578691 LAP3 0.59 5.12 0.42 1.13e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17001868 0.568 rs9611314 chr22:40735798 C/G cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs7615952 0.741 rs13314845 chr3:125644782 C/T cg05084668 chr3:125655381 ALG1L -0.75 -6.07 -0.48 1.41e-8 Blood pressure (smoking interaction); TGCT cis rs9549260 0.755 rs4325426 chr13:41216437 C/A cg21288729 chr13:41239152 FOXO1 0.97 10.09 0.67 7.57e-18 Red blood cell count; TGCT cis rs6876348 0.564 rs2577427 chr5:128311818 C/T cg02841155 chr5:128301328 SLC27A6 -0.34 -4.51 -0.38 1.51e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs56104184 0.775 rs56146968 chr19:49398847 A/G cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs797680 0.856 rs569414 chr1:93784901 G/A cg27528825 chr2:159282178 CCDC148 -0.33 -6.67 -0.51 7.68e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs394563 0.591 rs237028 chr6:149718650 C/T cg16235748 chr6:149772707 ZC3H12D -0.44 -4.9 -0.4 2.87e-6 Dupuytren's disease; TGCT cis rs3125734 0.607 rs7923556 chr10:64024648 A/G cg09941381 chr10:64027924 RTKN2 -0.37 -5.64 -0.45 1.1e-7 Rheumatoid arthritis; TGCT cis rs7107174 0.901 rs10899473 chr11:78042983 A/C cg12700464 chr11:78128424 GAB2 -0.66 -4.71 -0.39 6.53e-6 Testicular germ cell tumor; TGCT cis rs6582630 0.576 rs2387836 chr12:38560070 A/G cg26384229 chr12:38710491 ALG10B 0.5 4.68 0.39 7.47e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1205863 1.000 rs209816 chr6:11951031 A/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs7659604 0.521 rs6822155 chr4:122673274 C/A cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.9e-6 Type 2 diabetes; TGCT cis rs1670533 1.000 rs2100411 chr4:1074412 T/C cg20887711 chr4:1340912 KIAA1530 0.7 5.55 0.45 1.64e-7 Recombination rate (females); TGCT cis rs2832191 1.000 rs2832191 chr21:30489300 A/C cg08807101 chr21:30365312 RNF160 -0.49 -4.44 -0.37 1.99e-5 Dental caries; TGCT cis rs7605378 0.658 rs4673507 chr2:200710167 G/C cg17644776 chr2:200775616 C2orf69 0.36 7.47 0.56 1.26e-11 Osteoporosis; TGCT cis rs244731 0.959 rs7724098 chr5:176659570 G/A cg16006841 chr5:176797999 RGS14 -0.56 -7.34 -0.55 2.42e-11 Urate levels in lean individuals; TGCT cis rs6688613 1.000 rs10918605 chr1:166955638 A/G cg07049167 chr1:166818506 POGK 0.21 4.52 0.38 1.43e-5 Refractive astigmatism; TGCT cis rs2749592 0.531 rs1208559 chr10:38221370 T/C cg25427524 chr10:38739819 LOC399744 0.41 8.54 0.61 4.1e-14 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9926296 0.632 rs9935559 chr16:89800529 C/T cg26513180 chr16:89883248 FANCA -0.7 -6.89 -0.53 2.49e-10 Vitiligo; TGCT cis rs6988636 1.000 rs6983795 chr8:124185296 T/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs597539 0.652 rs513359 chr11:68669496 A/T cg21862992 chr11:68658383 NA -0.46 -6.61 -0.51 1.04e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs427394 1.000 rs274672 chr5:6744176 G/A cg10857441 chr5:6722123 POLS -0.28 -6.81 -0.52 3.73e-10 Menopause (age at onset); TGCT cis rs17376456 0.825 rs35496867 chr5:93220400 T/C cg25358565 chr5:93447407 FAM172A 1.01 8.13 0.59 3.77e-13 Diabetic retinopathy; TGCT cis rs7565124 1.000 rs7568106 chr2:20261969 G/A cg00462460 chr2:20212509 MATN3 -0.43 -4.67 -0.39 7.63e-6 Major depressive disorder; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg07798593 chr10:80890238 ZMIZ1 0.65 6.82 0.52 3.47e-10 Gambling; TGCT cis rs2239547 0.522 rs2581823 chr3:53022076 C/G cg10802521 chr3:52805072 NEK4 0.59 5.34 0.43 4.31e-7 Schizophrenia; TGCT cis rs9357506 1.000 rs9367242 chr6:46312875 A/G cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs9796 0.870 rs2925345 chr15:41311799 T/C cg18705301 chr15:41695430 NDUFAF1 0.41 5.31 0.43 4.82e-7 Menopause (age at onset); TGCT cis rs7312933 0.670 rs10880269 chr12:42606135 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs597539 0.652 rs673821 chr11:68678718 G/T cg21963583 chr11:68658836 MRPL21 0.33 5.61 0.45 1.28e-7 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs903263 0.965 rs1057738 chr1:84670816 A/C cg09664975 chr1:84543551 PRKACB 0.49 4.69 0.39 7.19e-6 Breast cancer (male); TGCT cis rs4700695 0.668 rs20768 chr5:65484805 C/T cg21114390 chr5:65439923 SFRS12 -0.79 -7.23 -0.54 4.31e-11 Facial morphology (factor 19); TGCT cis rs34783982 0.529 rs6496536 chr15:89479975 C/T cg26213453 chr15:89455860 MFGE8 0.35 4.89 0.4 3.03e-6 Squamous cell lung carcinoma; TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg21237687 chr17:6899380 ALOX12 0.54 5.72 0.46 7.41e-8 Tonsillectomy; TGCT cis rs7336332 0.800 rs9805452 chr13:28047908 C/T cg22138327 chr13:27999177 GTF3A 0.77 6.42 0.5 2.58e-9 Weight; TGCT cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg08392591 chr16:89556376 ANKRD11 -0.63 -6.1 -0.48 1.24e-8 Multiple myeloma (IgH translocation); TGCT cis rs2075371 0.611 rs34573600 chr7:134018937 C/T cg11752832 chr7:134001865 SLC35B4 0.63 5.1 0.42 1.23e-6 Mean platelet volume; TGCT trans rs7618501 0.633 rs9861216 chr3:50059339 A/G cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT trans rs1974653 0.672 rs8139591 chr22:20093317 A/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs7919533 0.564 rs9415039 chr10:73522694 A/G cg00101602 chr10:73857843 ASCC1 0.28 4.58 0.38 1.11e-5 Monocyte count; TGCT cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs28595532 1.000 rs11938970 chr4:119660152 A/G cg14228332 chr4:119757509 SEC24D 1.03 5.69 0.46 8.65e-8 Cannabis dependence symptom count; TGCT cis rs1805008 0.535 rs7196459 chr16:90141477 G/T cg08547343 chr16:90038815 CENPBD1;AFG3L1 -1.08 -4.63 -0.38 8.94e-6 Skin colour saturation; TGCT cis rs4654899 0.833 rs10916919 chr1:21317524 A/G cg01072550 chr1:21505969 NA 0.46 6.94 0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs9894429 1.000 rs7213129 chr17:79581573 C/T cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs1483890 0.662 rs6780513 chr3:69405494 G/A cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9443645 0.901 rs9343843 chr6:79585625 C/T cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg06481639 chr22:41940642 POLR3H -0.72 -6.2 -0.49 7.62e-9 Vitiligo; TGCT cis rs78487399 0.808 rs6746058 chr2:43687542 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4924935 1.000 rs11658555 chr17:18817486 C/T cg26378065 chr17:18585709 ZNF286B -0.56 -4.72 -0.39 6.38e-6 Pancreatic cancer; TGCT cis rs17401966 0.838 rs12738317 chr1:10419663 C/T cg19773385 chr1:10388646 KIF1B -0.23 -5.38 -0.44 3.57e-7 Hepatocellular carcinoma; TGCT cis rs8067545 0.967 rs1034904 chr17:19927699 A/G cg13482628 chr17:19912719 NA -0.54 -4.7 -0.39 6.85e-6 Schizophrenia; TGCT cis rs9611565 0.573 rs9306355 chr22:42111896 A/T cg13695892 chr22:41940480 POLR3H 0.83 8.18 0.59 2.79e-13 Vitiligo; TGCT cis rs6831352 0.879 rs34360292 chr4:100051303 T/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs4285028 0.851 rs1986368 chr3:121710969 A/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.44 -0.5 2.36e-9 Multiple sclerosis; TGCT cis rs8017423 0.904 rs11622257 chr14:90715014 C/T cg04374321 chr14:90722782 PSMC1 -0.73 -7.29 -0.55 3.12e-11 Mortality in heart failure; TGCT cis rs614226 0.688 rs75111771 chr12:121009943 T/C cg01236616 chr12:121019343 POP5 -1.29 -12.97 -0.76 7.75e-25 Type 1 diabetes nephropathy; TGCT cis rs1903068 0.853 rs28411232 chr4:56000009 A/T cg01777861 chr4:56023843 NA 0.54 6.38 0.5 3.2e-9 Endometriosis; TGCT cis rs11190604 1.000 rs2295772 chr10:102265183 G/A cg23241863 chr10:102295624 HIF1AN 0.67 5.13 0.42 1.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9677476 0.516 rs1035620 chr2:232008305 C/T cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs9527 0.615 rs4917991 chr10:104783833 T/C cg04362960 chr10:104952993 NT5C2 0.65 5.54 0.45 1.73e-7 Arsenic metabolism; TGCT cis rs3771570 1.000 rs62186411 chr2:242236667 A/C cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs514406 0.505 rs405208 chr1:53176674 C/T cg22166914 chr1:53195759 ZYG11B 0.45 7.99 0.58 7.98e-13 Monocyte count; TGCT cis rs617219 0.737 rs1275103 chr5:78448105 C/G cg09550809 chr5:78407562 BHMT 0.39 5.46 0.44 2.54e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs11098499 0.645 rs72676059 chr4:120290828 C/G cg09307838 chr4:120376055 NA 0.58 5.75 0.46 6.63e-8 Corneal astigmatism; TGCT cis rs9372253 0.967 rs1055301 chr6:110713042 A/G cg00083206 chr6:110721305 DDO -0.4 -6.07 -0.48 1.44e-8 Platelet distribution width; TGCT cis rs9814567 0.896 rs2177602 chr3:134245866 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs950776 0.745 rs36045869 chr15:78929498 C/T cg06917634 chr15:78832804 PSMA4 0.61 4.77 0.39 5.17e-6 Sudden cardiac arrest; TGCT cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.7 5.87 0.47 3.73e-8 Mean platelet volume; TGCT cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg17345569 chr6:42928274 GNMT -0.48 -4.97 -0.41 2.22e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs992157 0.560 rs7578940 chr2:219083318 G/T cg00012203 chr2:219082015 ARPC2 -0.81 -9.36 -0.64 4.37e-16 Colorectal cancer; TGCT cis rs7954584 0.520 rs1169096 chr12:122465836 G/C cg13699009 chr12:122356056 WDR66 -0.22 -4.59 -0.38 1.05e-5 Mean corpuscular volume; TGCT cis rs6815814 0.731 rs4504266 chr4:38773754 G/A cg02016764 chr4:38805732 TLR1 -0.28 -4.73 -0.39 5.94e-6 Breast cancer; TGCT cis rs1008375 0.966 rs10489036 chr4:17697687 A/G cg18681998 chr4:17616180 MED28 0.82 7.76 0.57 2.71e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs798766 0.953 rs13123646 chr4:1740539 T/C cg05874882 chr4:1763078 NA -0.33 -4.56 -0.38 1.2e-5 Bladder cancer;Urinary bladder cancer; TGCT trans rs208520 0.526 rs9351542 chr6:66788571 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.09 -16.9 -0.84 5.6e-34 Exhaled nitric oxide output; TGCT cis rs6089584 0.888 rs6061973 chr20:60610870 C/T cg13665807 chr20:60559372 TAF4 -0.46 -4.94 -0.41 2.48e-6 Body mass index; TGCT cis rs6089829 0.962 rs6089826 chr20:61668595 G/A cg02380750 chr20:61661411 NA 0.34 5.98 0.47 2.24e-8 Prostate cancer (SNP x SNP interaction); TGCT trans rs208520 0.802 rs4710314 chr6:66883656 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -10.21 -0.68 4.02e-18 Exhaled nitric oxide output; TGCT cis rs6495122 0.699 rs3784789 chr15:75082552 C/G cg10253484 chr15:75165896 SCAMP2 -0.68 -6.01 -0.48 1.87e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs8064299 0.632 rs750018 chr17:72771637 C/T cg25054828 chr17:72772726 NAT9;TMEM104 0.61 5.64 0.45 1.09e-7 Monocyte count; TGCT cis rs7336332 0.628 rs9581854 chr13:28017782 C/T cg22138327 chr13:27999177 GTF3A 0.83 6.64 0.51 9e-10 Weight; TGCT cis rs7208859 0.673 rs73263755 chr17:29198972 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs709400 0.894 rs61996721 chr14:104061352 G/A cg26031613 chr14:104095156 KLC1 1.16 16.37 0.83 9.05e-33 Body mass index; TGCT cis rs7809950 0.954 rs2520243 chr7:107136973 T/C cg23024343 chr7:107201750 COG5 -0.35 -5.6 -0.45 1.3e-7 Coronary artery disease; TGCT trans rs17685 0.753 rs10262501 chr7:75668172 G/A cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2235642 0.821 rs8051895 chr16:1602811 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.42 -0.44 2.97e-7 Coronary artery disease; TGCT cis rs12134245 0.719 rs61798831 chr1:91996588 C/T cg02896835 chr1:92012615 NA -0.27 -4.59 -0.38 1.08e-5 Breast cancer; TGCT cis rs904251 0.766 rs1757175 chr6:37486694 T/C cg01843034 chr6:37503916 NA -0.52 -6.35 -0.5 3.64e-9 Cognitive performance; TGCT cis rs9929218 0.551 rs6499193 chr16:68727069 C/T cg01251360 chr16:68772225 CDH1 -0.28 -5.27 -0.43 5.8e-7 Colorectal cancer; TGCT cis rs9682041 0.877 rs6804688 chr3:170071191 T/G cg11886554 chr3:170076028 SKIL 0.55 4.58 0.38 1.11e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs78707713 0.535 rs3812705 chr10:71211146 A/G cg12610070 chr10:71211762 TSPAN15 -0.6 -6.98 -0.53 1.62e-10 Venous thromboembolism; TGCT cis rs1153858 1.000 rs8042786 chr15:45703539 T/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.67 0.45 9.65e-8 Homoarginine levels; TGCT cis rs6460942 1.000 rs17668923 chr7:12302873 A/T cg06484146 chr7:12443880 VWDE -0.54 -4.99 -0.41 2.02e-6 Coronary artery disease; TGCT cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg15659132 chr6:26577336 NA -0.56 -5.55 -0.45 1.62e-7 Schizophrenia; TGCT cis rs8038465 0.904 rs11852484 chr15:73988652 G/A cg15420318 chr15:73925796 NPTN 0.52 4.59 0.38 1.08e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9372498 0.536 rs9489428 chr6:118852935 T/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT cis rs1218582 0.772 rs4845689 chr1:154885524 A/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs12681288 0.792 rs4735972 chr8:998618 A/C cg04851639 chr8:1020857 NA -0.35 -5.87 -0.47 3.72e-8 Schizophrenia; TGCT cis rs9644630 0.932 rs4922048 chr8:19360814 A/G cg01280390 chr8:19363452 CSGALNACT1 0.26 4.62 0.38 9.55e-6 Oropharynx cancer; TGCT cis rs2224391 0.590 rs72813700 chr6:5275531 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -1.06 -5.42 -0.44 2.94e-7 Height; TGCT cis rs736408 0.509 rs3774349 chr3:52722335 A/C cg07507251 chr3:52567010 NT5DC2 0.48 7.06 0.54 1.05e-10 Bipolar disorder; TGCT cis rs4862750 0.957 rs2375916 chr4:187903923 A/G cg22105103 chr4:187893119 NA 0.31 4.48 0.37 1.66e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2295359 1.000 rs736197 chr1:67607135 G/T cg12940439 chr1:67600707 NA 0.59 6.16 0.48 9.5e-9 Psoriasis; TGCT trans rs1814175 0.645 rs6486022 chr11:49776137 A/G cg11707556 chr5:10655725 ANKRD33B -0.46 -11.72 -0.72 8.37e-22 Height; TGCT cis rs12908161 1.000 rs35726233 chr15:85337800 C/T cg17173187 chr15:85201210 NMB 0.57 6.39 0.5 3.07e-9 Schizophrenia; TGCT cis rs7666738 0.830 rs28818180 chr4:98953625 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.846 rs6570700 chr6:145931552 A/G cg23711669 chr6:146136114 FBXO30 0.83 8.63 0.61 2.46e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs10470893 chr4:99038756 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs60843830 1.000 rs55753056 chr2:243929 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.69 6.48 0.5 1.91e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1403694 0.695 rs11924390 chr3:186433099 T/C cg12454167 chr3:186435060 KNG1 0.49 8.15 0.59 3.31e-13 Blood protein levels; TGCT cis rs12780845 0.522 rs725355 chr10:17202865 T/C cg01003015 chr10:17271136 VIM -0.52 -4.71 -0.39 6.42e-6 Homocysteine levels; TGCT cis rs10501293 1.000 rs1425850 chr11:43109833 T/C cg03447554 chr11:43094025 NA -0.5 -6.92 -0.53 2.09e-10 Cognitive performance; TGCT cis rs380904 0.963 rs410822 chr8:144574611 A/C cg09317036 chr8:144635547 GSDMD 0.49 4.58 0.38 1.12e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg05738196 chr6:26577821 NA -0.89 -10.62 -0.69 4e-19 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.624 rs303436 chr10:30731893 G/T cg12408189 chr10:30722286 MAP3K8 -0.45 -4.65 -0.39 8.34e-6 Inflammatory bowel disease; TGCT cis rs9914544 0.932 rs11870265 chr17:18820985 A/T cg26378065 chr17:18585709 ZNF286B 0.53 4.75 0.39 5.64e-6 Educational attainment (years of education); TGCT cis rs9303401 0.659 rs7216648 chr17:56790858 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs1218582 0.772 rs12069356 chr1:154849771 C/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.71 -0.57 3.44e-12 Prostate cancer; TGCT cis rs7267979 0.866 rs2424699 chr20:25257462 G/A cg03522245 chr20:25566470 NINL 0.62 6.57 0.51 1.22e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4727027 0.933 rs6961605 chr7:148870108 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.59 0.38 1.07e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg25703541 chr22:24373054 LOC391322 -0.84 -8.98 -0.63 3.58e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg17054783 chr10:134559939 INPP5A 0.23 4.48 0.37 1.64e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9902453 1.000 rs59274738 chr17:28437635 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.57 0.51 1.22e-9 Coffee consumption (cups per day); TGCT cis rs8033133 0.958 rs6420956 chr15:25309559 T/C cg14481604 chr15:25334117 SNORD116-22 -0.28 -5.87 -0.47 3.68e-8 Blood osmolality (transformed sodium); TGCT cis rs11096990 0.964 rs6842390 chr4:39263482 C/G cg14806045 chr4:39367699 RFC1 0.59 4.63 0.38 8.92e-6 Cognitive function; TGCT cis rs9303401 0.614 rs12947982 chr17:57140301 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.8 0.46 5.11e-8 Cognitive test performance; TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg24503407 chr1:205819492 PM20D1 0.59 8.33 0.6 1.3e-13 Menarche (age at onset); TGCT cis rs1008375 0.932 rs3846356 chr4:17614176 C/T cg10189774 chr4:17578691 LAP3 0.65 5.49 0.44 2.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg07061783 chr6:25882402 NA -0.89 -10.69 -0.69 2.63e-19 Urate levels; TGCT cis rs4517514 0.509 rs11018875 chr11:89876356 T/C cg14505434 chr11:89522851 NA 0.45 4.46 0.37 1.82e-5 Trans fatty acid levels; TGCT cis rs28595532 0.920 rs115090643 chr4:119729825 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs225245 0.817 rs225284 chr17:33933006 A/C cg05299278 chr17:33885742 SLFN14 0.21 4.44 0.37 1.98e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs9913156 0.517 rs8065068 chr17:4611453 A/T cg19197139 chr17:4613644 ARRB2 0.73 6.59 0.51 1.14e-9 Lymphocyte counts; TGCT cis rs9611565 0.512 rs5758464 chr22:42171300 A/G cg06634786 chr22:41940651 POLR3H 0.95 6.61 0.51 1.01e-9 Vitiligo; TGCT cis rs17253792 0.822 rs10148122 chr14:56146694 G/T cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT trans rs1814175 0.817 rs3974439 chr11:50022607 G/A cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg07424592 chr7:64974309 NA 1.36 8.08 0.59 4.97e-13 Diabetic kidney disease; TGCT cis rs11190604 1.000 rs11190607 chr10:102303614 C/T cg23241863 chr10:102295624 HIF1AN 0.7 5.14 0.42 1.02e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs17767294 0.541 rs733743 chr6:28327371 C/G cg08851530 chr6:28072375 NA -1.2 -6.39 -0.5 3.01e-9 Parkinson's disease; TGCT cis rs5769707 0.681 rs739236 chr22:50041602 A/G cg05373962 chr22:49881684 NA -0.34 -5.66 -0.45 1.01e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1801251 1.000 rs1446308 chr2:233639309 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs6952808 0.609 rs6950151 chr7:1953521 T/C cg22963979 chr7:1858916 MAD1L1 -0.38 -5.73 -0.46 7.15e-8 Bipolar disorder and schizophrenia; TGCT cis rs9868809 0.656 rs13324119 chr3:48710606 G/C cg00383909 chr3:49044727 WDR6 1.06 6.18 0.49 8.32e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs11741688 0.557 rs6897783 chr5:178330574 G/A cg09339527 chr5:178322752 ZFP2 -0.29 -4.85 -0.4 3.57e-6 Sleep duration; TGCT cis rs9467773 0.596 rs3001369 chr6:26670969 C/T cg09904177 chr6:26538194 HMGN4 0.63 5.4 0.44 3.34e-7 Intelligence (multi-trait analysis); TGCT cis rs9638182 0.725 rs80189144 chr7:72939939 T/C cg14087351 chr7:73037990 MLXIPL -0.57 -4.52 -0.38 1.4e-5 Triglycerides; TGCT cis rs6540559 0.546 rs735693 chr1:210033988 A/C cg04352962 chr1:209979756 IRF6 0.76 5.37 0.43 3.69e-7 Cleft lip with or without cleft palate; TGCT cis rs6918586 0.658 rs198840 chr6:26112164 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.07e-9 Schizophrenia; TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg19536664 chr17:6899085 ALOX12 0.38 6.05 0.48 1.62e-8 Tonsillectomy; TGCT cis rs3809566 0.676 rs62013179 chr15:63329601 T/G cg00520135 chr15:63333846 TPM1 -0.4 -4.9 -0.4 2.95e-6 Platelet count; TGCT cis rs1348850 0.914 rs7587604 chr2:178309848 T/A cg22681709 chr2:178499509 PDE11A -0.34 -4.47 -0.37 1.72e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2229238 0.911 rs4379670 chr1:154439865 T/A cg13067139 chr1:155221277 FAM189B -0.2 -4.56 -0.38 1.22e-5 Coronary heart disease; TGCT cis rs4665809 1.000 rs3910272 chr2:26287842 T/A cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs2762353 0.595 rs10498728 chr6:25751320 A/T cg12310025 chr6:25882481 NA -0.78 -8.1 -0.59 4.37e-13 Blood metabolite levels; TGCT cis rs1799949 1.000 rs4793191 chr17:41204377 A/G cg05368731 chr17:41323189 NBR1 1.1 11.12 0.71 2.38e-20 Menopause (age at onset); TGCT cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg16497277 chr3:49208875 KLHDC8B -0.53 -5.13 -0.42 1.09e-6 Menarche (age at onset); TGCT cis rs1887596 0.705 rs9551299 chr13:27166335 A/G cg01312412 chr13:27282625 NA 0.3 5.33 0.43 4.43e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115437723 chr4:119741828 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs8014204 0.762 rs10139018 chr14:75274292 T/C cg06637938 chr14:75390232 RPS6KL1 0.55 4.91 0.4 2.81e-6 Caffeine consumption; TGCT cis rs12541335 0.639 rs4871994 chr8:22206038 G/A cg02463440 chr8:22132932 PIWIL2 0.26 5.02 0.41 1.78e-6 Hypertriglyceridemia; TGCT cis rs10504229 0.636 rs117439064 chr8:58055279 A/G cg11062466 chr8:58055876 NA 0.43 4.64 0.38 8.85e-6 Developmental language disorder (linguistic errors); TGCT cis rs2862064 1.000 rs2862064 chr5:156445827 C/G cg12943317 chr5:156479607 HAVCR1 -0.38 -5.2 -0.42 8.06e-7 Platelet count; TGCT cis rs7666738 0.830 rs1559859 chr4:99024325 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1372520 0.532 rs2583972 chr4:90747411 T/G cg15133208 chr4:90757351 SNCA -0.5 -5.75 -0.46 6.42e-8 Neuroticism; TGCT cis rs7681440 0.838 rs1348224 chr4:90761946 G/A cg14346243 chr4:90757452 SNCA -0.57 -5.61 -0.45 1.24e-7 Dementia with Lewy bodies; TGCT cis rs3935685 0.874 rs11072663 chr15:77999542 A/G cg03457338 chr15:78040120 NA -0.22 -5.61 -0.45 1.24e-7 Intelligence (multi-trait analysis); TGCT cis rs4886920 0.694 rs7163336 chr15:78087772 A/G cg25212270 chr15:78015279 NA 0.23 4.82 0.4 4.04e-6 Neuroticism; TGCT cis rs3806843 0.766 rs2530239 chr5:140062547 C/T cg19875535 chr5:140030758 IK -0.35 -5.93 -0.47 2.81e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7264396 0.790 rs6121015 chr20:34243017 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.68 -0.39 7.38e-6 Total cholesterol levels; TGCT cis rs453301 0.598 rs1025395 chr8:8836603 G/C cg11995313 chr8:8860691 ERI1 -0.51 -4.48 -0.37 1.68e-5 Joint mobility (Beighton score); TGCT cis rs4727027 0.866 rs1405124 chr7:148779618 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.54 5.0 0.41 1.93e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9682041 0.660 rs34158232 chr3:170115360 T/C cg11886554 chr3:170076028 SKIL 0.62 4.82 0.4 4.11e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs614226 0.748 rs78714658 chr12:121009944 G/A cg01236616 chr12:121019343 POP5 -1.29 -12.97 -0.76 7.75e-25 Type 1 diabetes nephropathy; TGCT cis rs524281 0.773 rs11227413 chr11:65883696 G/A cg00563793 chr11:65837595 PACS1 0.56 4.58 0.38 1.12e-5 Electroencephalogram traits; TGCT trans rs525455 1.000 rs1659837 chr10:13103112 C/T cg21721093 chr17:8906386 NA 0.64 6.7 0.52 6.38e-10 Platelet aggregation; TGCT cis rs7809950 0.678 rs7790080 chr7:107031322 G/A cg23024343 chr7:107201750 COG5 -0.46 -6.18 -0.49 8.6e-9 Coronary artery disease; TGCT cis rs3096299 0.935 rs3102387 chr16:89432276 A/C cg06640241 chr16:89574553 SPG7 0.68 6.82 0.52 3.51e-10 Multiple myeloma (IgH translocation); TGCT cis rs11059919 1 rs11059919 chr12:129289190 G/A cg09035930 chr12:129282057 SLC15A4 0.57 11.13 0.71 2.23e-20 Systemic lupus erythematosus; TGCT cis rs1395 0.744 rs11126932 chr2:27476282 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs7666738 0.830 rs17484966 chr4:99014432 T/C cg17366294 chr4:99064904 C4orf37 0.66 6.75 0.52 5.04e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6546537 0.911 rs4852898 chr2:69872797 C/T cg10773587 chr2:69614142 GFPT1 -0.78 -6.44 -0.5 2.35e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg09060608 chr5:178986726 RUFY1 0.61 7.14 0.54 6.87e-11 Lung cancer; TGCT cis rs4953076 0.573 rs6734443 chr2:44408282 G/C cg04920474 chr2:44395004 PPM1B 0.59 5.92 0.47 2.94e-8 Height; TGCT cis rs2075165 0.901 rs2296374 chr1:156287403 T/C cg16558208 chr1:156270281 VHLL 0.28 5.05 0.41 1.52e-6 Tonsillectomy; TGCT cis rs10927875 0.526 rs2179615 chr1:16282426 G/A cg21385522 chr1:16154831 NA -0.94 -9.6 -0.65 1.15e-16 Dilated cardiomyopathy; TGCT cis rs13082711 0.595 rs34453788 chr3:27330153 T/C cg02860705 chr3:27208620 NA 0.48 7.4 0.55 1.83e-11 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.7 4.86 0.4 3.52e-6 Platelet count; TGCT cis rs6663390 0.831 rs3754171 chr1:208086939 T/C cg03990033 chr1:208084030 CD34 0.54 5.61 0.45 1.26e-7 Facial morphology (factor 18); TGCT cis rs4455778 0.659 rs11185624 chr7:49028252 T/A cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT trans rs7698623 0.850 rs6532020 chr4:88768928 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs12477438 0.501 rs1133977 chr2:99741984 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.73 -7.04 -0.53 1.18e-10 Chronic sinus infection; TGCT cis rs9916302 0.904 rs4795357 chr17:37569551 T/C cg07936489 chr17:37558343 FBXL20 -0.63 -4.91 -0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.791 rs11735105 chr4:98937357 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs732765 0.819 rs714788 chr14:75320043 G/A cg06637938 chr14:75390232 RPS6KL1 -0.59 -5.02 -0.41 1.72e-6 Non-small cell lung cancer; TGCT cis rs4665809 1.000 rs750450 chr2:26324631 A/G cg25036284 chr2:26402008 FAM59B -0.54 -4.69 -0.39 7.11e-6 Gut microbiome composition (summer); TGCT cis rs2046867 0.908 rs1994627 chr3:72783628 A/G cg25664220 chr3:72788482 NA 0.53 6.61 0.51 1e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6141769 0.542 rs2064934 chr20:31314757 C/G cg13636640 chr20:31349939 DNMT3B -0.52 -4.54 -0.38 1.34e-5 Subjective well-being; TGCT cis rs250677 0.958 rs10056942 chr5:148416114 C/A cg18129178 chr5:148520854 ABLIM3 -0.4 -5.63 -0.45 1.17e-7 Breast cancer; TGCT cis rs8177253 1.000 rs8177247 chr3:133479499 T/G cg20276088 chr3:133502917 NA -0.24 -4.96 -0.41 2.28e-6 Iron status biomarkers; TGCT cis rs76878669 0.561 rs11823140 chr11:66098322 G/T cg18002602 chr11:66138449 SLC29A2 -0.52 -6.32 -0.49 4.39e-9 Educational attainment (years of education); TGCT cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg13607699 chr17:42295918 UBTF 0.84 7.55 0.56 8.34e-12 Total body bone mineral density; TGCT cis rs6933660 0.745 rs3778608 chr6:151738131 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.67 0.39 7.55e-6 Menarche (age at onset); TGCT cis rs2677744 0.626 rs868547 chr15:91498760 G/A cg22570213 chr15:91497863 RCCD1 0.39 4.78 0.39 4.9100000000000004e-06 Attention deficit hyperactivity disorder; TGCT trans rs57221529 0.655 rs72704791 chr5:547896 A/G cg11887960 chr12:57824829 NA 1.12 8.48 0.61 5.54e-14 Lung disease severity in cystic fibrosis; TGCT cis rs36051895 0.587 rs7035915 chr9:5238253 C/T cg02405213 chr9:5042618 JAK2 -0.73 -9.52 -0.65 1.88e-16 Pediatric autoimmune diseases; TGCT cis rs7714584 1.000 rs59531858 chr5:150247063 T/G cg22134413 chr5:150180641 NA 1.17 8.71 0.62 1.61e-14 Crohn's disease; TGCT cis rs4746818 1.000 rs7091695 chr10:70964997 A/G cg11621586 chr10:70884670 VPS26A -1.11 -7.83 -0.58 1.87e-12 Left atrial antero-posterior diameter; TGCT cis rs4149178 0.722 rs9472031 chr6:43293101 C/T cg07522644 chr6:43142093 SRF -0.66 -4.69 -0.39 7e-6 Urate levels; TGCT cis rs3820068 0.705 rs4646031 chr1:15834648 A/G cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs2153535 0.580 rs1034272 chr6:8469335 G/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs6430585 0.528 rs586964 chr2:136652491 G/A cg07169764 chr2:136633963 MCM6 1.25 12.43 0.74 1.55e-23 Corneal structure; TGCT cis rs4460629 0.521 rs7367897 chr1:155083289 A/T cg23973274 chr1:155060172 NA -0.25 -4.51 -0.38 1.5e-5 Serum magnesium levels; TGCT cis rs7809950 1.000 rs3801944 chr7:107255548 T/C cg23024343 chr7:107201750 COG5 0.36 5.64 0.45 1.1e-7 Coronary artery disease; TGCT cis rs1843834 0.539 rs6739735 chr2:225405253 A/G cg12698349 chr2:225449008 CUL3 -0.76 -6.29 -0.49 4.91e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs1218582 0.772 rs877343 chr1:154910012 A/G cg16680214 chr1:154839983 KCNN3 -0.35 -7.11 -0.54 8.04e-11 Prostate cancer; TGCT cis rs868036 0.681 rs4776978 chr15:68108305 A/G cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs1784581 0.802 rs9458430 chr6:162426517 G/T cg17173639 chr6:162384350 PARK2 -0.43 -7.5 -0.56 1.09e-11 Itch intensity from mosquito bite; TGCT cis rs9914544 0.966 rs9906795 chr17:18816740 G/A cg26306683 chr17:18585705 ZNF286B 0.57 4.98 0.41 2.06e-6 Educational attainment (years of education); TGCT cis rs4819052 0.851 rs28676615 chr21:46676576 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11122272 0.766 rs2024879 chr1:231528638 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.09e-9 Hemoglobin concentration; TGCT cis rs7432375 0.901 rs1017882 chr3:136357705 T/C cg12473912 chr3:136751656 NA 0.36 5.06 0.41 1.5e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs4595586 0.545 rs12814188 chr12:39380853 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2204008 0.720 rs11170774 chr12:38021722 C/T cg26384229 chr12:38710491 ALG10B -0.7 -6.14 -0.48 1.04e-8 Bladder cancer; TGCT cis rs2963155 0.518 rs56150733 chr5:142765099 T/C cg17617527 chr5:142782415 NR3C1 0.8 4.92 0.4 2.65e-6 Breast cancer; TGCT cis rs10992471 0.576 rs9409664 chr9:95070095 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.63 -6.09 -0.48 1.29e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9291683 0.632 rs13101785 chr4:10042915 T/A cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.29e-14 Bone mineral density; TGCT trans rs7618501 1.000 rs34614773 chr3:49753003 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.870 rs2291199 chr4:1244267 A/G cg03303774 chr4:1407052 NA 0.29 4.76 0.39 5.36e-6 Obesity-related traits; TGCT cis rs3733585 0.775 rs13124007 chr4:10043931 G/C cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13242816 0.881 rs35210394 chr7:116104911 C/G cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs6121246 0.567 rs2889488 chr20:30185758 G/A cg21427119 chr20:30132790 HM13 -0.38 -5.63 -0.45 1.14e-7 Mean corpuscular hemoglobin; TGCT cis rs4566357 1.000 rs6436650 chr2:227925097 C/T cg11843606 chr2:227700838 RHBDD1 -0.5 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs9942416 0.660 rs10462356 chr5:74987108 C/T cg19683494 chr5:74908142 NA 0.59 6.26 0.49 5.62e-9 Age-related disease endophenotypes; TGCT cis rs644799 1.000 rs568668 chr11:95528209 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs611744 0.506 rs4735054 chr8:109261780 A/C cg21045802 chr8:109455806 TTC35 -0.83 -8.7 -0.62 1.71e-14 Dupuytren's disease; TGCT cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2675662 0.525 rs12264025 chr10:75494450 A/G cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Psoriasis vulgaris;Psoriasis; TGCT cis rs9902453 0.584 rs3809790 chr17:27955540 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.85 -7.8 -0.57 2.14e-12 Coffee consumption (cups per day); TGCT cis rs2820315 0.867 rs2819346 chr1:201882087 A/C cg12730843 chr1:201915899 LMOD1 -0.24 -4.5 -0.38 1.52e-5 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs7727544 0.716 rs10058655 chr5:131570896 A/T cg21474247 chr5:131268130 NA 0.32 4.64 0.38 8.57e-6 Blood metabolite levels; TGCT cis rs617219 0.698 rs72764983 chr5:78513806 T/C cg09550809 chr5:78407562 BHMT 0.41 5.66 0.45 9.78e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.632 rs10815166 chr9:5149920 T/G cg02405213 chr9:5042618 JAK2 -0.75 -9.73 -0.66 5.75e-17 Pediatric autoimmune diseases; TGCT cis rs7666738 0.753 rs7698541 chr4:98986351 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9910055 0.571 rs10208 chr17:42300278 C/T cg13607699 chr17:42295918 UBTF 1.12 14.59 0.79 1.1e-28 Total body bone mineral density; TGCT cis rs11190604 0.767 rs7392696 chr10:102182141 G/A cg16005271 chr10:102321736 NA 0.46 4.67 0.39 7.62e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7255045 0.788 rs10424001 chr19:12948462 A/G cg06537894 chr19:12978706 MAST1 -0.49 -4.44 -0.37 1.98e-5 Mean corpuscular volume; TGCT cis rs7246657 0.722 rs954504 chr19:38045394 A/G cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs9896850 0.513 rs10445407 chr17:79261809 A/C cg27412613 chr17:79183705 AZI1 0.23 4.48 0.37 1.65e-5 Frontotemporal dementia; TGCT cis rs7617773 0.780 rs11706277 chr3:48360433 A/G cg11946769 chr3:48343235 NME6 0.8 7.06 0.54 1.03e-10 Coronary artery disease; TGCT cis rs7312933 0.533 rs17551006 chr12:42848738 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.52 4.93 0.4 2.62e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9811216 1.000 rs9831661 chr3:169528523 A/C cg08193579 chr3:169529701 LRRC34 -0.29 -4.58 -0.38 1.13e-5 Neutrophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs11105298 0.685 rs117578503 chr12:89836672 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2594989 0.887 rs7643330 chr3:11442093 A/G cg00170343 chr3:11313890 ATG7 0.66 4.99 0.41 1.96e-6 Circulating chemerin levels; TGCT cis rs908922 0.676 rs1970283 chr1:152495619 G/C cg20991723 chr1:152506922 NA 0.46 6.22 0.49 6.97e-9 Hair morphology; TGCT cis rs10461617 0.541 rs860581 chr5:56150537 A/G cg20203395 chr5:56204925 C5orf35 -0.65 -4.7 -0.39 6.83e-6 Type 2 diabetes; TGCT cis rs7552404 0.691 rs1770890 chr1:76401117 A/G cg10523679 chr1:76189770 ACADM -0.8 -7.4 -0.55 1.79e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2562456 0.876 rs7252585 chr19:21657943 C/T cg01304269 chr19:21688519 ZNF429 -0.57 -4.69 -0.39 7.09e-6 Pain; TGCT cis rs7552404 0.765 rs211717 chr1:76106969 G/A cg10523679 chr1:76189770 ACADM -0.92 -10.1 -0.67 7.29e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs854572 1.000 rs854572 chr7:94954696 C/G cg19678392 chr7:94953810 PON1 -0.69 -7.82 -0.57 1.92e-12 Paraoxonase activity; TGCT cis rs4803468 1.000 rs6508977 chr19:41909346 A/G cg09537434 chr19:41945824 ATP5SL -0.92 -10.69 -0.69 2.72e-19 Height; TGCT cis rs2777491 0.957 rs919961 chr15:41651721 A/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.46 -0.68 9.68e-19 Ulcerative colitis; TGCT cis rs116095464 0.558 rs59113266 chr5:279965 T/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs7666738 0.830 rs115712871 chr4:98954535 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs60843830 0.964 rs7584915 chr2:264227 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.72 6.94 0.53 1.98e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2456568 0.900 rs2456559 chr11:93668858 A/T cg26875233 chr11:93583750 C11orf90 -0.46 -5.59 -0.45 1.4e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg05890377 chr2:74357713 NA 0.52 7.0 0.53 1.44e-10 Gestational age at birth (maternal effect); TGCT cis rs7772486 0.875 rs854145 chr6:146349650 C/T cg23711669 chr6:146136114 FBXO30 0.87 9.51 0.65 1.9e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs8031584 0.752 rs1852035 chr15:31184803 C/G cg08109568 chr15:31115862 NA -0.36 -4.85 -0.4 3.7e-6 Huntington's disease progression; TGCT cis rs709400 0.550 rs11626905 chr14:104016066 C/T cg26031613 chr14:104095156 KLC1 0.77 6.32 0.49 4.33e-9 Body mass index; TGCT cis rs4805272 0.924 rs1363326 chr19:29325650 A/G cg15000279 chr19:29285009 NA -0.52 -5.64 -0.45 1.07e-7 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs6088580 0.634 rs4911423 chr20:32999386 T/A cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs7528419 0.895 rs583104 chr1:109821307 G/T cg00908766 chr1:109817496 CELSR2 0.46 4.77 0.39 5.1e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs263156 0.902 rs263120 chr6:142893857 T/A cg18419694 chr6:143832440 FUCA2 -0.39 -4.57 -0.38 1.18e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg07806771 chr7:64541737 NA 0.44 4.55 0.38 1.26e-5 Calcium levels; TGCT cis rs9894429 0.966 rs10871499 chr17:79589006 G/A cg21028142 chr17:79581711 NPLOC4 0.29 6.83 0.52 3.44e-10 Eye color traits; TGCT cis rs780094 0.585 rs7586601 chr2:27584666 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.33 4.5 0.37 1.57e-5 Calcium levels;Fasting blood insulin;Metabolic traits;Triglyceride levels;Fasting plasma glucose;Urate levels in overweight individuals;Urate levels in obese individuals;Uric acid levels;Height;Age-related diseases, mortality and associated endophenotypes;Renal underexcretion gout;Fasting blood glucose (BMI interaction);Urate levels;Gondoic acid (20:1n-9) levels;Fasting blood insulin (BMI interaction);Triglycerides;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid);Type 2 diabetes;Nonalcoholic fatty liver disease;Hypertriglyceridemia;C-reactive protein;Age-related disease endophenotypes;LDL cholesterol;Metabolic syndrome;Crohn's disease;Alcohol consumption (drinks per week);Homeostasis model assessment of insulin resistance;Alcohol consumption;Red blood cell count;Fasting blood glucose; TGCT cis rs4699052 0.625 rs11734572 chr4:104288620 G/A cg16532752 chr4:104119610 CENPE -0.5 -4.75 -0.39 5.48e-6 Testicular germ cell tumor; TGCT cis rs35160687 0.901 rs12620833 chr2:86472870 T/C cg03171300 chr2:86307199 POLR1A 0.33 5.61 0.45 1.25e-7 Night sleep phenotypes; TGCT cis rs6967414 0.786 rs6463578 chr7:6753050 C/A cg09896999 chr7:6746977 ZNF12 -0.59 -6.6 -0.51 1.06e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.86 0.4 3.51e-6 Lymphocyte counts; TGCT cis rs10256972 0.567 rs2960850 chr7:1211649 A/G cg16145915 chr7:1198662 ZFAND2A -0.56 -6.9 -0.53 2.43e-10 Longevity;Endometriosis; TGCT cis rs7769051 1.000 rs9493443 chr6:133121349 C/T cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs6964587 0.934 rs1544377 chr7:91687351 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs3087591 1.000 rs7220483 chr17:29577248 G/A cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.51 -0.56 1.01e-11 Hip circumference; TGCT cis rs9915657 0.870 rs35271702 chr17:70140516 G/A cg06234051 chr17:70120541 SOX9 -0.24 -4.77 -0.39 4.99e-6 Thyroid hormone levels; TGCT cis rs2742417 0.967 rs2742441 chr3:45748429 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1891498 0.703 rs10900397 chr1:147243153 G/A cg17941330 chr1:147245494 GJA5 0.36 4.53 0.38 1.36e-5 Cognitive performance; TGCT cis rs881375 0.867 rs10818484 chr9:123661194 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.08 0.42 1.34e-6 Rheumatoid arthritis; TGCT cis rs7089973 0.604 rs11196929 chr10:116582080 G/C cg03647239 chr10:116582469 FAM160B1 0.58 5.63 0.45 1.16e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9549260 0.755 rs17061503 chr13:41246758 A/G cg21288729 chr13:41239152 FOXO1 -0.97 -9.76 -0.66 4.95e-17 Red blood cell count; TGCT cis rs6840360 0.558 rs2709821 chr4:152342190 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.36 -0.5 3.48e-9 Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs3806692 chr3:53080987 C/G cg27565382 chr3:53032988 SFMBT1 0.41 4.69 0.39 6.97e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6840360 0.642 rs7678823 chr4:152357119 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT trans rs1005277 0.579 rs2474567 chr10:38382492 C/T cg17830980 chr10:43048298 ZNF37B -0.85 -10.98 -0.7 5.08e-20 Extrinsic epigenetic age acceleration; TGCT cis rs1008375 0.931 rs10008337 chr4:17593849 G/C cg10189774 chr4:17578691 LAP3 0.71 6.05 0.48 1.59e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1814175 0.645 rs10128731 chr11:50023554 G/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs8072100 0.666 rs9913014 chr17:45460189 C/T cg08085267 chr17:45401833 C17orf57 -0.5 -5.47 -0.44 2.38e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs11650776 1 rs11650776 chr17:37641402 G/A cg07936489 chr17:37558343 FBXL20 -0.61 -4.85 -0.4 3.6e-6 Lung function (FEV1); TGCT cis rs739496 0.615 rs57072497 chr12:112145217 A/T cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs644799 0.544 rs555556 chr11:95618425 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.56 5.58 0.45 1.46e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1008375 0.966 rs2159582 chr4:17695655 T/C cg18681998 chr4:17616180 MED28 0.76 7.09 0.54 8.93e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12643440 0.538 rs4698536 chr4:17142175 C/T cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs9733 0.596 rs72702573 chr1:150689050 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT trans rs57221529 0.766 rs17563576 chr5:560476 A/G cg11887960 chr12:57824829 NA 1.2 9.62 0.65 1.04e-16 Lung disease severity in cystic fibrosis; TGCT cis rs2243480 0.901 rs778730 chr7:65823325 T/A cg18252515 chr7:66147081 NA -1.22 -7.4 -0.55 1.81e-11 Diabetic kidney disease; TGCT cis rs3020333 0.875 rs2982573 chr6:152010534 A/G cg22157087 chr6:152012887 ESR1 0.19 4.55 0.38 1.24e-5 Total body bone mineral density; TGCT cis rs611744 0.967 rs684093 chr8:109199355 G/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs3617 0.625 rs7617468 chr3:52849549 T/C cg11645453 chr3:52864694 ITIH4 0.28 5.37 0.43 3.78e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs669446 0.533 rs6429638 chr1:44211010 A/G cg12908607 chr1:44402522 ARTN -0.63 -7.47 -0.56 1.22e-11 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs4930103 0.534 rs2063550 chr11:1979223 G/C cg02850416 chr11:1986266 NA 0.27 4.54 0.38 1.31e-5 DNA methylation (parent-of-origin);DNA methylation (variation); TGCT cis rs7666738 0.830 rs2167892 chr4:99048503 G/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.548 rs2320740 chr12:38166421 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.68 0.57 4.17e-12 Bladder cancer; TGCT cis rs7666738 0.783 rs10028584 chr4:98962404 C/T cg05340658 chr4:99064831 C4orf37 0.53 5.93 0.47 2.85e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs2204008 0.626 rs11520260 chr12:38330092 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs1461503 0.932 rs11218909 chr11:122842613 C/T cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.42e-7 Menarche (age at onset); TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg18538332 chr22:24372958 LOC391322 -0.98 -11.74 -0.73 7.55e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8038465 0.592 rs1542580 chr15:73935834 C/G cg15420318 chr15:73925796 NPTN 0.64 6.67 0.51 7.56e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2013441 1.000 rs4924810 chr17:20071819 T/C cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs7659604 1.000 rs7689722 chr4:122665955 T/C cg19748678 chr4:122722346 EXOSC9 0.55 5.31 0.43 4.92e-7 Type 2 diabetes; TGCT cis rs986417 1.000 rs761555 chr14:61109543 T/C cg27398547 chr14:60952738 C14orf39 1.62 8.87 0.62 6.55e-15 Gut microbiota (bacterial taxa); TGCT cis rs926938 0.520 rs969273 chr1:115256669 G/A cg12756093 chr1:115239321 AMPD1 -0.42 -5.65 -0.45 1.02e-7 Autism; TGCT cis rs1005277 0.540 rs1814077 chr10:37992018 G/C cg25427524 chr10:38739819 LOC399744 -0.32 -6.24 -0.49 6.41e-9 Extrinsic epigenetic age acceleration; TGCT cis rs7208859 0.673 rs1347360 chr17:28914532 T/C cg13385521 chr17:29058706 SUZ12P 0.87 5.44 0.44 2.76e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4665809 0.590 rs1368902 chr2:26440576 T/C cg25036284 chr2:26402008 FAM59B -0.65 -5.19 -0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs6089829 0.889 rs6122348 chr20:61663921 C/T cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs11249608 0.548 rs34881171 chr5:178451932 C/T cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs7264396 0.690 rs2425172 chr20:34443893 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.76 5.1 0.42 1.22e-6 Alzheimer's disease; TGCT cis rs904251 0.861 rs1757171 chr6:37487044 T/C cg08126542 chr6:37504118 NA -0.45 -5.97 -0.47 2.38e-8 Cognitive performance; TGCT cis rs9914988 0.945 rs9279 chr17:27187636 G/T cg20469991 chr17:27169893 C17orf63 0.69 5.05 0.41 1.51e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs11626933 1.000 rs45463097 chr14:90744188 G/A cg14092571 chr14:90743983 NA -0.3 -6.18 -0.48 8.66e-9 Gut microbiota (bacterial taxa); TGCT cis rs17376456 0.825 rs10072232 chr5:93398890 G/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs477895 0.838 rs11607007 chr11:64007976 C/T cg23719950 chr11:63933701 MACROD1 -0.68 -5.67 -0.45 9.3e-8 Mean platelet volume; TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg25767906 chr1:53392781 SCP2 -0.61 -7.2 -0.54 5.02e-11 Monocyte count; TGCT cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs6754311 0.593 rs10186843 chr2:136586958 C/A cg07169764 chr2:136633963 MCM6 -0.61 -5.69 -0.46 8.62e-8 Mosquito bite size; TGCT cis rs17331151 0.505 rs35325270 chr3:52556369 C/T cg07884673 chr3:53033167 SFMBT1 0.67 4.74 0.39 5.74e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7104764 0.673 rs3782118 chr11:222620 T/C cg18336825 chr11:236787 PSMD13;SIRT3 0.96 9.78 0.66 4.29e-17 Menarche (age at onset); TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg01585852 chr22:24235823 MIF -0.23 -5.13 -0.42 1.1e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg09177884 chr7:1199841 ZFAND2A -0.62 -6.49 -0.5 1.83e-9 Longevity;Endometriosis; TGCT cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.85 0.47 4.05e-8 Height; TGCT cis rs1348850 0.598 rs12616259 chr2:178503803 C/T cg22681709 chr2:178499509 PDE11A -0.53 -6.55 -0.51 1.38e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT trans rs56011263 0.687 rs4690188 chr4:703930 G/C cg12575136 chr18:32820987 ZNF397 0.79 9.58 0.65 1.34e-16 White blood cell count; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg10150615 chr22:24372951 LOC391322 -0.76 -6.17 -0.48 9.07e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7666738 0.761 rs28758886 chr4:99059704 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs9929218 0.551 rs7201437 chr16:68727130 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.58 7.41 0.55 1.68e-11 Colorectal cancer; TGCT cis rs7917772 0.503 rs7902306 chr10:104290462 C/T cg05855489 chr10:104503620 C10orf26 -0.55 -4.64 -0.38 8.67e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3820928 0.874 rs6740108 chr2:227889559 G/T cg11843606 chr2:227700838 RHBDD1 0.52 4.82 0.4 4.12e-6 Pulmonary function; TGCT cis rs3818285 0.504 rs7100154 chr10:111650150 T/C cg00817464 chr10:111662876 XPNPEP1 -0.29 -5.07 -0.41 1.38e-6 Superior crus of antihelix expression; TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg27535305 chr1:53392650 SCP2 -0.26 -4.97 -0.41 2.16e-6 Monocyte count; TGCT cis rs11190604 1.000 rs12219789 chr10:102213778 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg05985448 chr10:134359359 INPP5A 0.23 4.99 0.41 2.01e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9467773 0.526 rs10946817 chr6:26364056 C/T cg05738196 chr6:26577821 NA -0.63 -6.61 -0.51 1.01e-9 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.503 rs2031602 chr10:104307955 G/C cg05855489 chr10:104503620 C10orf26 -0.6 -5.25 -0.43 6.32e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs60871478 0.704 rs62432895 chr7:822050 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.48 4.66 0.39 7.91e-6 Cerebrospinal P-tau181p levels; TGCT cis rs9796 0.870 rs8042088 chr15:41337487 C/T cg18705301 chr15:41695430 NDUFAF1 0.39 5.29 0.43 5.42e-7 Menopause (age at onset); TGCT cis rs4455778 0.580 rs10215945 chr7:49096423 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs1862618 0.573 rs2034245 chr5:56243685 T/C cg12311346 chr5:56204834 C5orf35 0.82 7.65 0.57 4.95e-12 Initial pursuit acceleration; TGCT cis rs7772486 0.790 rs9497435 chr6:146265340 C/A cg23711669 chr6:146136114 FBXO30 -0.85 -9.7 -0.66 6.73e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs868036 0.718 rs8025790 chr15:68076399 G/T cg05925327 chr15:68127851 NA -0.51 -4.94 -0.41 2.52e-6 Restless legs syndrome; TGCT cis rs9372253 1.000 rs9384740 chr6:110716207 G/A cg19196401 chr6:110721138 DDO -0.5 -7.33 -0.55 2.59e-11 Platelet distribution width; TGCT cis rs2882877 0.621 rs17198934 chr2:190378371 C/G cg10752008 chr2:190445175 SLC40A1 0.61 4.5 0.37 1.53e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs9902453 0.817 rs62068620 chr17:28167674 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs2832191 0.791 rs4817270 chr21:30480368 G/A cg08807101 chr21:30365312 RNF160 -0.66 -6.19 -0.49 8.16e-9 Dental caries; TGCT cis rs28595532 0.920 rs114966881 chr4:119761078 C/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6088580 0.634 rs6120650 chr20:33039973 G/A cg06115741 chr20:33292138 TP53INP2 0.55 4.85 0.4 3.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs7681440 0.904 rs28507349 chr4:90767063 G/A cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs7666738 0.830 rs6825211 chr4:98807698 A/T cg18180107 chr4:99064573 C4orf37 0.53 5.05 0.41 1.51e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9796 0.870 rs8030306 chr15:41261821 T/A cg18705301 chr15:41695430 NDUFAF1 -0.45 -5.88 -0.47 3.61e-8 Menopause (age at onset); TGCT cis rs1372520 0.623 rs2583975 chr4:90748488 T/C cg14346243 chr4:90757452 SNCA -0.6 -4.87 -0.4 3.27e-6 Neuroticism; TGCT cis rs9733 0.519 rs1134067 chr1:150721175 G/T cg09365446 chr1:150670422 GOLPH3L 0.32 4.73 0.39 6.05e-6 Tonsillectomy; TGCT cis rs80282103 0.618 rs57514701 chr10:1146169 G/A cg18964960 chr10:1102726 WDR37 0.98 4.57 0.38 1.15e-5 Glomerular filtration rate (creatinine); TGCT cis rs17401966 1.000 rs11121532 chr1:10277898 G/T cg21474053 chr1:11182049 MTOR 0.19 4.49 0.37 1.58e-5 Hepatocellular carcinoma; TGCT cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg06238570 chr21:40685208 BRWD1 0.72 6.84 0.52 3.16e-10 Cognitive function; TGCT cis rs67311347 0.544 rs67533651 chr3:40338367 T/A cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs9926296 0.572 rs2376878 chr16:89885161 G/A cg26513180 chr16:89883248 FANCA 0.75 7.52 0.56 9.5e-12 Vitiligo; TGCT cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9303401 0.573 rs34097494 chr17:57171917 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs12579753 0.810 rs1922565 chr12:82135348 T/C cg07988820 chr12:82153109 PPFIA2 -0.66 -7.47 -0.56 1.25e-11 Resting heart rate; TGCT cis rs2013441 1.000 rs2526464 chr17:20075052 A/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs6938 0.534 rs7495739 chr15:75185670 C/T cg10253484 chr15:75165896 SCAMP2 0.53 4.88 0.4 3.15e-6 Breast cancer; TGCT cis rs7264396 0.635 rs6060682 chr20:34506331 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs950169 0.580 rs35516100 chr15:85195430 C/T cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.97e-7 Schizophrenia; TGCT cis rs4803468 1.000 rs10413735 chr19:41921071 C/T cg09537434 chr19:41945824 ATP5SL -0.92 -10.71 -0.69 2.31e-19 Height; TGCT cis rs9929218 1.000 rs28549017 chr16:68758828 G/C cg01251360 chr16:68772225 CDH1 0.29 4.95 0.41 2.34e-6 Colorectal cancer; TGCT cis rs7635838 0.785 rs2606735 chr3:11400714 A/C cg00170343 chr3:11313890 ATG7 0.64 6.13 0.48 1.1e-8 HDL cholesterol; TGCT cis rs2046867 0.818 rs11928620 chr3:72863209 A/C cg25664220 chr3:72788482 NA -0.56 -7.03 -0.53 1.24e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9910055 0.529 rs425038 chr17:42182028 T/C cg19774624 chr17:42201019 HDAC5 0.7 6.68 0.51 7.15e-10 Total body bone mineral density; TGCT cis rs6693567 0.545 rs7411534 chr1:150447269 C/T cg09579323 chr1:150459698 TARS2 0.53 5.04 0.41 1.58e-6 Migraine; TGCT cis rs478304 0.934 rs517115 chr11:65526988 C/T cg17480646 chr11:65405466 SIPA1 0.43 5.38 0.43 3.62e-7 Acne (severe); TGCT cis rs34638657 0.732 rs7206093 chr16:82201884 G/A cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs7666738 0.791 rs6833691 chr4:98951508 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs896854 0.967 rs2879813 chr8:95960947 A/G cg13393036 chr8:95962371 TP53INP1 -0.65 -8.97 -0.63 3.91e-15 Type 2 diabetes; TGCT cis rs910316 1.000 rs11159117 chr14:75584867 C/T cg08847533 chr14:75593920 NEK9 0.96 10.92 0.7 7.35e-20 Height; TGCT cis rs6500602 0.623 rs9929311 chr16:4510426 T/C cg08645402 chr16:4508243 NA 0.2 4.93 0.4 2.6e-6 Schizophrenia; TGCT cis rs7666738 0.678 rs7670805 chr4:99008763 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.0 0.53 1.44e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs908922 0.742 rs499913 chr1:152476743 T/A cg20991723 chr1:152506922 NA 0.46 5.83 0.46 4.43e-8 Hair morphology; TGCT cis rs11874712 0.966 rs9962380 chr18:43678706 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.14 0.42 1.03e-6 Migraine - clinic-based; TGCT cis rs7666738 0.578 rs1989109 chr4:98881246 T/A cg05340658 chr4:99064831 C4orf37 0.54 6.13 0.48 1.06e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2688608 0.839 rs2633310 chr10:75594050 G/T cg19442545 chr10:75533431 FUT11 0.31 4.56 0.38 1.19e-5 Inflammatory bowel disease; TGCT cis rs1008375 1.000 rs2315556 chr4:17670861 T/C cg18681998 chr4:17616180 MED28 0.9 10.33 0.68 1.96e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28595532 0.920 rs116205107 chr4:119730910 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs12220238 1.000 rs11000924 chr10:75972311 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1420338 0.839 rs918036 chr7:34181859 A/G cg01275685 chr7:34179230 BMPER -0.27 -4.9 -0.4 2.92e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs12368653 0.789 rs17852479 chr12:58126234 C/A cg12615879 chr12:58013172 SLC26A10 0.52 6.43 0.5 2.5e-9 Multiple sclerosis; TGCT cis rs1218582 0.804 rs4845678 chr1:154853295 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.67 -6.67 -0.51 7.76e-10 Prostate cancer; TGCT cis rs3902035 0.929 rs62423967 chr6:119010336 C/G cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs4332037 0.539 rs3823624 chr7:2110346 T/C cg25834613 chr7:1915315 MAD1L1 -0.52 -5.04 -0.41 1.64e-6 Bipolar disorder; TGCT cis rs5167 0.743 rs57204168 chr19:45496776 A/G cg13119609 chr19:45449297 APOC2 0.23 4.79 0.4 4.64e-6 Blood protein levels; TGCT cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg16680214 chr1:154839983 KCNN3 0.34 7.2 0.54 4.97e-11 Prostate cancer; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg02953382 chr22:24373134 LOC391322 0.84 9.86 0.66 2.82e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7192750 0.586 rs12935795 chr16:71987452 G/C cg06353428 chr16:71660113 MARVELD3 0.74 6.62 0.51 9.68e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7829975 0.501 rs4840353 chr8:8580570 A/G cg15556689 chr8:8085844 FLJ10661 -0.53 -4.54 -0.38 1.31e-5 Mood instability; TGCT cis rs6570726 0.599 rs9403725 chr6:145897622 A/T cg13319975 chr6:146136371 FBXO30 0.7 6.43 0.5 2.5e-9 Lobe attachment (rater-scored or self-reported); TGCT trans rs941408 1.000 rs1640271 chr19:2799979 C/T cg22153745 chr1:153894579 GATAD2B -0.67 -7.26 -0.55 3.76e-11 Total cholesterol levels; TGCT cis rs6570726 0.791 rs414600 chr6:145879606 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs889312 0.500 rs33328 chr5:56143419 T/C cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs6754311 0.773 rs309137 chr2:136765951 A/G cg07169764 chr2:136633963 MCM6 0.61 5.66 0.45 9.86e-8 Mosquito bite size; TGCT cis rs2456568 0.695 rs908748 chr11:93690148 G/A cg17595323 chr11:93583763 C11orf90 0.4 4.99 0.41 1.98e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7811142 1.000 rs60844404 chr7:100080474 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs9942416 0.660 rs193344 chr5:74977854 T/C cg19683494 chr5:74908142 NA -0.58 -6.12 -0.48 1.14e-8 Age-related disease endophenotypes; TGCT cis rs7617773 0.780 rs4541431 chr3:48365218 G/C cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs4919669 0.668 rs10883737 chr10:104320898 C/G cg05855489 chr10:104503620 C10orf26 0.73 4.71 0.39 6.65e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs7120118 0.517 rs10838694 chr11:47351760 G/A cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.26e-7 HDL cholesterol; TGCT cis rs7103648 0.897 rs11606287 chr11:47407439 C/A cg20307385 chr11:47447363 PSMC3 1.03 12.12 0.74 8.55e-23 Diastolic blood pressure;Systolic blood pressure; TGCT trans rs10504390 0.656 rs80033165 chr8:66478523 T/A cg18118147 chr19:51128640 SYT3 -0.77 -6.82 -0.52 3.51e-10 IgG glycosylation; TGCT cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg05985448 chr10:134359359 INPP5A 0.21 4.6 0.38 1.02e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4851254 0.550 rs13402299 chr2:100659409 C/T cg22139774 chr2:100720529 AFF3 -0.46 -5.13 -0.42 1.08e-6 Intelligence (multi-trait analysis); TGCT cis rs13064411 0.696 rs6799610 chr3:113248748 A/C cg18753928 chr3:113234510 CCDC52 0.66 5.4 0.44 3.29e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs4268898 0.662 rs2288074 chr2:24413595 C/T cg02683114 chr2:24398427 C2orf84 -0.22 -4.48 -0.37 1.69e-5 Asthma; TGCT cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg05368731 chr17:41323189 NBR1 1.08 10.88 0.7 9.36e-20 Menopause (age at onset); TGCT cis rs4455778 0.692 rs2191297 chr7:49010701 A/G cg26309511 chr7:48887640 NA -0.45 -5.58 -0.45 1.42e-7 Lung cancer in never smokers; TGCT cis rs6978712 0.858 rs17714259 chr7:127147097 T/A cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs9883204 1.000 rs2877716 chr3:123094451 A/G cg04890266 chr3:123102914 ADCY5 -0.36 -5.11 -0.42 1.17e-6 Birth weight; TGCT cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4499344 0.730 rs259285 chr19:33164697 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.87 9.38 0.64 3.95e-16 Mean platelet volume; TGCT cis rs4372836 1.000 rs2276547 chr2:28975107 G/C cg09522027 chr2:28974177 PPP1CB -0.57 -4.92 -0.4 2.68e-6 Body mass index; TGCT cis rs4455778 0.580 rs34005483 chr7:49094307 A/G cg26309511 chr7:48887640 NA 0.5 6.45 0.5 2.29e-9 Lung cancer in never smokers; TGCT cis rs10782582 0.593 rs11163915 chr1:76130199 C/T cg10523679 chr1:76189770 ACADM -0.68 -7.05 -0.53 1.11e-10 Daytime sleep phenotypes; TGCT cis rs7635838 0.819 rs2454482 chr3:11534031 C/T cg00170343 chr3:11313890 ATG7 0.68 6.36 0.5 3.46e-9 HDL cholesterol; TGCT cis rs7432375 0.901 rs7648531 chr3:136462223 T/A cg12473912 chr3:136751656 NA -0.36 -5.05 -0.41 1.55e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs2455799 0.553 rs2262664 chr3:15768097 A/T cg16303742 chr3:15540471 COLQ -0.26 -4.96 -0.41 2.26e-6 Mean platelet volume; TGCT cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg23205692 chr1:25664452 TMEM50A 0.52 5.38 0.43 3.59e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs896854 0.967 rs10956933 chr8:95967688 C/G cg16049864 chr8:95962084 TP53INP1 -0.77 -10.92 -0.7 7.16e-20 Type 2 diabetes; TGCT cis rs7674212 0.540 rs2711897 chr4:104023567 C/T cg16532752 chr4:104119610 CENPE -0.55 -4.85 -0.4 3.68e-6 Type 2 diabetes; TGCT cis rs7666738 0.830 rs3852123 chr4:98697586 A/G cg17366294 chr4:99064904 C4orf37 0.71 7.45 0.56 1.41e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs75686122 0.892 rs75861389 chr8:104664993 G/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7223966 1.000 rs2665826 chr17:61944924 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs78456975 0.657 rs116217838 chr2:1569173 T/C cg01028140 chr2:1542097 TPO -0.33 -5.14 -0.42 1.03e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs62380364 0.542 rs2457979 chr5:88039660 T/A cg22951263 chr5:87985283 NA -0.55 -5.93 -0.47 2.83e-8 Intelligence (multi-trait analysis); TGCT cis rs425277 1.000 rs809912 chr1:2078385 C/T cg24578937 chr1:2090814 PRKCZ 0.32 8.03 0.58 6.41e-13 Height; TGCT trans rs208520 0.690 rs12202913 chr6:66734198 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs17221829 0.965 rs10830361 chr11:89456273 C/A cg02982614 chr11:89391479 FOLH1B -0.27 -4.88 -0.4 3.23e-6 Anxiety in major depressive disorder; TGCT cis rs12477438 0.765 rs13390672 chr2:99589829 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs2302045 1.000 rs75811104 chr2:242052338 C/A cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs10114408 0.959 rs7869842 chr9:96644932 C/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs514406 0.861 rs7526275 chr1:53245849 C/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs7264396 0.790 rs6058293 chr20:34248891 T/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs5769765 0.773 rs58375955 chr22:50312630 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs597539 0.615 rs629426 chr11:68671104 A/G cg06028808 chr11:68637592 NA 0.53 6.91 0.53 2.23e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6933660 0.720 rs6914656 chr6:151753421 C/G cg17179660 chr6:151773299 C6orf211;RMND1 -0.53 -4.81 -0.4 4.28e-6 Menarche (age at onset); TGCT cis rs10904887 1.000 rs10904887 chr10:17188641 T/C cg01003015 chr10:17271136 VIM -0.55 -4.96 -0.41 2.23e-6 Telomere length; TGCT cis rs6138458 1.000 rs227651 chr20:24929834 A/G cg26195577 chr20:24973756 C20orf3 1.2 12.06 0.73 1.2e-22 Blood protein levels; TGCT cis rs797680 0.856 rs4240966 chr1:93774812 C/A cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs916888 0.773 rs538628 chr17:44787313 G/C cg07870213 chr5:140052090 DND1 0.67 7.91 0.58 1.22e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6938 0.662 rs12487 chr15:75136694 A/G cg13906792 chr15:75199810 C15orf17 -0.22 -4.96 -0.41 2.28e-6 Breast cancer; TGCT cis rs10858047 0.883 rs12040830 chr1:115108738 T/C cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg20064778 chr22:24384315 GSTT1 -0.48 -4.58 -0.38 1.1e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4455778 0.580 rs7796664 chr7:49117787 C/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7086627 0.515 rs11202963 chr10:82210392 A/G cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs7949030 0.653 rs17773169 chr11:62318530 G/T cg13298116 chr11:62369859 EML3;MTA2 0.65 9.64 0.65 9.48e-17 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.966 rs2263204 chr20:25377688 A/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4455778 0.659 rs4607558 chr7:49023949 C/T cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs10876993 0.928 rs1689586 chr12:58079586 A/T cg15848620 chr12:58087721 OS9 -0.72 -5.98 -0.47 2.25e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs9902453 0.765 rs2628180 chr17:28101723 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs6450176 1.000 rs4334836 chr5:53300835 T/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2456568 0.802 rs10765638 chr11:93636171 A/T cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.07e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9814567 1.000 rs6439487 chr3:134260860 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs77457752 0.525 rs10961293 chr9:13894250 A/G cg12973904 chr7:149457885 NA 0.45 6.78 0.52 4.25e-10 Breast cancer; TGCT cis rs6921919 0.583 rs9468370 chr6:28368940 C/T cg18815343 chr6:28367644 ZSCAN12 -0.55 -5.37 -0.43 3.79e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9906944 0.657 rs4643373 chr17:47123423 T/C cg10950924 chr17:47092072 IGF2BP1 -0.34 -4.44 -0.37 1.97e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7208859 0.673 rs9889755 chr17:29234505 A/G cg18442181 chr17:29233375 C17orf42 0.83 5.39 0.44 3.45e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs589448 0.902 rs315134 chr12:69762713 G/A cg14784868 chr12:69753453 YEATS4 0.89 10.48 0.69 8.4e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs6484504 0.532 rs10835756 chr11:31267622 C/T cg14844989 chr11:31128820 NA -0.25 -4.84 -0.4 3.76e-6 Red blood cell count; TGCT cis rs4819052 0.851 rs2838833 chr21:46665160 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 6.9 0.53 2.4e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2201728 0.967 rs2866151 chr4:100198512 A/T cg07219303 chr4:100140905 ADH6 -0.34 -5.1 -0.42 1.22e-6 Cardiac Troponin-T levels; TGCT cis rs6500596 0.506 rs1530088 chr16:4439131 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.4 5.45 0.44 2.62e-7 Schizophrenia; TGCT cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.53 5.1 0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs394563 0.775 rs412894 chr6:149781175 G/A cg16235748 chr6:149772707 ZC3H12D -0.42 -4.67 -0.39 7.79e-6 Dupuytren's disease; TGCT cis rs7659604 1.000 rs10005932 chr4:122664782 T/C cg19748678 chr4:122722346 EXOSC9 0.57 5.5 0.44 2.07e-7 Type 2 diabetes; TGCT trans rs8073060 0.586 rs225305 chr17:33921160 C/T cg19694781 chr19:47549865 TMEM160 -0.59 -12.7 -0.75 3.37e-24 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6951245 1.000 rs77760339 chr7:1083927 G/T cg03188948 chr7:1209495 NA 0.63 5.17 0.42 8.92e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1062177 1.000 rs2915877 chr5:151150601 C/G cg12924095 chr5:151150029 G3BP1 0.35 5.09 0.42 1.31e-6 Preschool internalizing problems; TGCT cis rs1670533 1.000 rs6827357 chr4:1059202 A/C cg27284194 chr4:1044797 NA 0.67 5.6 0.45 1.29e-7 Recombination rate (females); TGCT cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg21016266 chr12:122356598 WDR66 0.52 7.48 0.56 1.17e-11 Mean corpuscular volume; TGCT cis rs28595532 1.000 rs114912871 chr4:119697004 G/C cg21605333 chr4:119757512 SEC24D 1.41 7.28 0.55 3.45e-11 Cannabis dependence symptom count; TGCT cis rs12497850 0.931 rs7626445 chr3:49114544 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.4 -0.44 3.33e-7 Parkinson's disease; TGCT cis rs9796 0.621 rs1659227 chr15:41472398 G/A cg18705301 chr15:41695430 NDUFAF1 0.52 7.17 0.54 5.94e-11 Menopause (age at onset); TGCT trans rs17685 0.753 rs6953665 chr7:75769049 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1975974 1.000 rs4889703 chr17:21721663 T/C cg18423549 chr17:21743878 NA -0.49 -4.76 -0.39 5.3e-6 Psoriasis; TGCT cis rs916888 0.610 rs199436 chr17:44789285 C/T cg17911788 chr17:44343683 NA 0.43 5.1 0.42 1.21e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs875971 0.767 rs12668005 chr7:65909021 T/C cg11764359 chr7:65958608 NA 0.55 5.07 0.41 1.42e-6 Aortic root size; TGCT cis rs1800469 0.965 rs12983775 chr19:41857439 G/A cg09537434 chr19:41945824 ATP5SL -0.5 -4.59 -0.38 1.06e-5 Colorectal cancer; TGCT cis rs344364 0.636 rs344363 chr16:1972548 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.43 -4.45 -0.37 1.9e-5 Glomerular filtration rate in chronic kidney disease; TGCT cis rs10465746 0.687 rs6576954 chr1:84323701 C/T cg10977910 chr1:84465055 TTLL7 -0.59 -5.85 -0.46 4.14e-8 Obesity-related traits; TGCT cis rs7119 0.931 rs59418918 chr15:77833110 A/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.68 -0.39 7.4e-6 Type 2 diabetes; TGCT cis rs7264396 0.635 rs6058346 chr20:34481043 G/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.27 -4.47 -0.37 1.76e-5 Total cholesterol levels; TGCT cis rs9926296 0.557 rs11076618 chr16:89807705 T/C cg08627397 chr16:89984028 MC1R -0.3 -4.76 -0.39 5.38e-6 Vitiligo; TGCT cis rs896854 0.654 rs4735337 chr8:95973465 T/C cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs3008870 0.920 rs975452 chr1:67480190 A/T cg03991309 chr1:68237761 GNG12 0.27 4.49 0.37 1.6e-5 Lymphocyte percentage of white cells; TGCT trans rs3102947 0.539 rs3111425 chr2:8487785 A/G cg10290200 chr7:128481295 FLNC 0.29 6.91 0.53 2.3e-10 IgE levels; TGCT cis rs6918586 0.658 rs1572982 chr6:26094367 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.7 6.6 0.51 1.09e-9 Schizophrenia; TGCT cis rs6690583 0.623 rs12042018 chr1:85436937 T/C cg20280350 chr1:85513789 MCOLN3 -0.67 -4.5 -0.37 1.52e-5 Serum sulfate level; TGCT cis rs28595532 0.920 rs114314373 chr4:119639128 G/A cg11846333 chr4:119757529 SEC24D 0.95 4.68 0.39 7.54e-6 Cannabis dependence symptom count; TGCT cis rs7590720 0.531 rs6435932 chr2:216906030 T/C cg12620499 chr2:216877984 MREG 0.76 7.54 0.56 8.75e-12 Alcohol dependence; TGCT cis rs7652177 0.810 rs12629746 chr3:171933069 C/A cg03587978 chr3:172165696 GHSR 0.29 4.61 0.38 9.75e-6 Height; TGCT cis rs8103278 0.793 rs59093775 chr19:46374037 G/A cg11657440 chr19:46296263 DMWD -0.64 -5.92 -0.47 2.94e-8 Coronary artery disease; TGCT cis rs6740322 0.895 rs13384080 chr2:43557363 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.54 -0.51 1.45e-9 Coronary artery disease; TGCT cis rs17376456 0.542 rs2043979 chr5:93120782 T/A cg21475434 chr5:93447410 FAM172A -0.64 -6.04 -0.48 1.69e-8 Diabetic retinopathy; TGCT cis rs6089829 0.643 rs6011545 chr20:61660038 G/A cg08045932 chr20:61659980 NA 0.36 5.47 0.44 2.34e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.51 4.52 0.38 1.44e-5 Prudent dietary pattern; TGCT cis rs10411936 1.000 rs11878602 chr19:16555153 A/C cg14704714 chr19:15740395 CYP4F8 -0.26 -4.57 -0.38 1.16e-5 White blood cell count;Multiple sclerosis; TGCT cis rs11098499 0.820 rs11737395 chr4:120520704 C/G cg09307838 chr4:120376055 NA 0.69 6.58 0.51 1.18e-9 Corneal astigmatism; TGCT cis rs6088590 1.000 rs6087632 chr20:33407704 A/C cg06115741 chr20:33292138 TP53INP2 0.65 5.43 0.44 2.82e-7 Coronary artery disease; TGCT cis rs6904897 0.538 rs4639353 chr6:135224328 A/G cg22676075 chr6:135203613 NA -0.64 -7.12 -0.54 7.73e-11 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs610932 0.517 rs600550 chr11:59997666 C/T cg18570331 chr11:60101691 MS4A6E 0.51 4.64 0.38 8.87e-6 Alzheimer's disease; TGCT cis rs10089 1.000 rs73337363 chr5:127483597 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.64e-13 Ileal carcinoids; TGCT cis rs28489187 0.617 rs2840319 chr1:85886224 C/T cg16011679 chr1:85725395 C1orf52 -0.48 -4.45 -0.37 1.91e-5 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs6938 0.534 rs7495739 chr15:75185670 C/T cg09165964 chr15:75287851 SCAMP5 -0.53 -5.08 -0.42 1.33e-6 Breast cancer; TGCT cis rs10465746 0.780 rs11163865 chr1:84366917 C/T cg10977910 chr1:84465055 TTLL7 0.66 6.56 0.51 1.31e-9 Obesity-related traits; TGCT cis rs6952808 0.630 rs1860832 chr7:2161849 G/A cg04267008 chr7:1944627 MAD1L1 -0.37 -5.02 -0.41 1.78e-6 Bipolar disorder and schizophrenia; TGCT cis rs7666738 0.791 rs10013680 chr4:99023030 G/C cg18180107 chr4:99064573 C4orf37 0.56 4.91 0.4 2.86e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.877 rs10044066 chr5:93437580 T/C cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs78487399 0.710 rs57696714 chr2:43626521 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -4.87 -0.4 3.39e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs250677 0.522 rs3763022 chr5:148381078 A/G cg18129178 chr5:148520854 ABLIM3 -0.35 -4.86 -0.4 3.43e-6 Breast cancer; TGCT cis rs67311347 1.000 rs9834052 chr3:40399060 G/A cg13683864 chr3:40499215 RPL14 -1.02 -10.8 -0.7 1.43e-19 Renal cell carcinoma; TGCT cis rs7511006 1.000 rs7364173 chr22:50681029 C/T cg08875078 chr22:50639485 SELO -0.5 -4.87 -0.4 3.27e-6 Obesity-related traits; TGCT cis rs7010267 0.711 rs10955908 chr8:119904557 C/A cg17171407 chr8:119960777 TNFRSF11B -0.29 -5.06 -0.41 1.5e-6 Total body bone mineral density (age 45-60); TGCT cis rs1801251 1.000 rs4973054 chr2:233710713 G/C cg25237894 chr2:233734115 C2orf82 -0.33 -5.94 -0.47 2.71e-8 Coronary artery disease; TGCT cis rs9393692 0.875 rs9358917 chr6:26284417 T/C cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.01e-7 Educational attainment; TGCT cis rs2749592 0.531 rs1208559 chr10:38221370 T/C cg02002400 chr10:38691563 CDC10L 0.38 4.66 0.39 7.94e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs10782582 0.569 rs1770892 chr1:76389359 T/C cg10523679 chr1:76189770 ACADM -0.51 -4.58 -0.38 1.1e-5 Daytime sleep phenotypes; TGCT cis rs10858300 1.000 rs7873100 chr9:137856843 C/G cg13620366 chr9:138839624 UBAC1 -0.23 -4.45 -0.37 1.9e-5 Blood protein levels; TGCT cis rs7647973 0.667 rs6446286 chr3:49681704 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs308403 0.509 rs9990804 chr4:123671984 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.84 0.73 4.22e-22 Blood protein levels; TGCT cis rs9733 0.596 rs12089731 chr1:150647798 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs2760061 0.583 rs708123 chr1:228220495 A/G cg02753203 chr1:228287806 NA 0.4 8.17 0.59 2.97e-13 Diastolic blood pressure; TGCT cis rs3774830 0.846 rs11732645 chr4:5454829 C/T cg26943120 chr4:5472116 STK32B 0.22 4.79 0.4 4.66e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4654899 0.714 rs12123093 chr1:21114416 C/T cg01072550 chr1:21505969 NA -0.47 -7.09 -0.54 8.84e-11 Superior frontal gyrus grey matter volume; TGCT cis rs9916302 0.904 rs8066704 chr17:37477218 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs4499344 0.657 rs4805768 chr19:33049678 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.21 -0.49 7.33e-9 Mean platelet volume; TGCT cis rs12541335 0.579 rs59283125 chr8:22212311 G/A cg00420450 chr8:22132641 PIWIL2 0.24 4.46 0.37 1.81e-5 Hypertriglyceridemia; TGCT cis rs9916302 0.904 rs2338755 chr17:37419317 C/T cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs6951245 0.529 rs10262070 chr7:1141738 C/T cg18402987 chr7:1209562 NA 0.46 4.72 0.39 6.39e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9788721 0.640 rs1394371 chr15:78724469 C/T cg18825076 chr15:78729989 IREB2 -0.33 -4.85 -0.4 3.63e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs9894429 0.572 rs112417725 chr17:79578219 A/G cg21028142 chr17:79581711 NPLOC4 -0.29 -5.95 -0.47 2.56e-8 Eye color traits; TGCT cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg10295955 chr4:187884368 NA -0.99 -15.24 -0.81 3.38e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg22105103 chr4:187893119 NA -0.35 -5.02 -0.41 1.76e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg27535305 chr1:53392650 SCP2 -0.24 -4.73 -0.39 5.98e-6 Monocyte count; TGCT cis rs769267 1.000 rs12985655 chr19:19442434 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs2120019 0.938 rs8040169 chr15:75370958 C/A cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT cis rs727563 0.593 rs5758461 chr22:42162189 G/C cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.03 0.41 1.71e-6 Menopause (age at onset); TGCT cis rs875971 0.964 rs778735 chr7:65814809 C/A cg11764359 chr7:65958608 NA 0.62 5.53 0.44 1.82e-7 Aortic root size; TGCT cis rs10791097 0.667 rs12363163 chr11:130744509 A/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -5.3 -0.43 5.11e-7 Developmental language disorder (linguistic errors); TGCT cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs3806843 0.808 rs6893708 chr5:140125922 T/C cg19875535 chr5:140030758 IK -0.34 -5.66 -0.45 1.01e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs76419734 0.510 rs1447097 chr4:106528633 C/A cg24545054 chr4:106630052 GSTCD;INTS12 0.82 4.67 0.39 7.63e-6 Post bronchodilator FEV1; TGCT cis rs12908161 1.000 rs11638290 chr15:85227636 C/T cg11189052 chr15:85197271 WDR73 0.75 6.3 0.49 4.8e-9 Schizophrenia; TGCT cis rs2836950 0.565 rs2150413 chr21:40614878 C/T cg11890956 chr21:40555474 PSMG1 -0.7 -6.96 -0.53 1.76e-10 Menarche (age at onset); TGCT cis rs78487399 0.808 rs17030818 chr2:43680318 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11585357 0.947 rs2977303 chr1:17611548 A/T cg08277548 chr1:17600880 PADI3 -0.96 -9.86 -0.66 2.8e-17 Hair shape; TGCT cis rs6964587 0.836 rs757040 chr7:91552016 A/G cg17063962 chr7:91808500 NA -0.84 -8.28 -0.6 1.62e-13 Breast cancer; TGCT cis rs7843479 0.601 rs10866827 chr8:21801141 G/A cg17168535 chr8:21777572 XPO7 0.81 8.33 0.6 1.25e-13 Mean corpuscular volume; TGCT cis rs4689592 0.503 rs56099074 chr4:7071259 A/G cg02503808 chr4:7069936 GRPEL1 -1.02 -8.95 -0.63 4.29e-15 Monocyte percentage of white cells; TGCT cis rs2836974 0.965 rs8131126 chr21:40655754 A/G cg11890956 chr21:40555474 PSMG1 1.04 11.03 0.7 3.96e-20 Cognitive function; TGCT cis rs11250097 0.549 rs11784897 chr8:11310442 G/A cg21775007 chr8:11205619 TDH -0.53 -4.87 -0.4 3.31e-6 Neuroticism; TGCT cis rs7582180 0.629 rs13031906 chr2:100939524 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs11247915 0.561 rs11583258 chr1:26624270 C/T cg23732845 chr1:26663426 AIM1L -0.35 -4.54 -0.38 1.3e-5 Obesity-related traits; TGCT cis rs11677370 0.561 rs13003140 chr2:3816759 G/T cg17052675 chr2:3827356 NA -0.44 -7.57 -0.56 7.21e-12 Type 2 diabetes; TGCT cis rs739496 0.614 rs9788231 chr12:112385665 A/C cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs2836974 0.897 rs2026265 chr21:40595517 G/A cg11890956 chr21:40555474 PSMG1 1.1 12.31 0.74 2.99e-23 Cognitive function; TGCT cis rs2836633 0.929 rs8130434 chr21:40036243 C/T cg05519781 chr21:40033154 ERG -0.7 -6.95 -0.53 1.88e-10 Coronary artery disease; TGCT cis rs9486719 0.948 rs12203657 chr6:96883285 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs12142240 0.698 rs68083747 chr1:46807416 T/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.05 0.48 1.59e-8 Alzheimer's disease; TGCT cis rs7654585 1.000 rs7654585 chr4:25942751 A/G cg10409131 chr4:25915609 C4orf52 0.75 7.82 0.57 1.99e-12 Obesity-related traits; TGCT cis rs709400 0.663 rs62007683 chr14:103894071 G/T cg26031613 chr14:104095156 KLC1 0.88 9.61 0.65 1.09e-16 Body mass index; TGCT cis rs4788570 0.543 rs4788820 chr16:71660115 G/C cg06353428 chr16:71660113 MARVELD3 1.57 12.81 0.75 1.9e-24 Intelligence (multi-trait analysis); TGCT cis rs854765 0.647 rs8066764 chr17:17974668 C/T cg04398451 chr17:18023971 MYO15A -0.36 -5.99 -0.47 2.14e-8 Total body bone mineral density; TGCT cis rs6542838 0.611 rs7588441 chr2:99518858 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.64 -0.38 8.77e-6 Fear of minor pain; TGCT cis rs13118159 0.550 rs2878607 chr4:1353310 G/C cg19318889 chr4:1322082 MAEA 0.27 6.66 0.51 7.93e-10 Longevity; TGCT cis rs77861329 1.000 rs9847092 chr3:52199453 T/C cg08692210 chr3:52188851 WDR51A 0.94 4.82 0.4 4.12e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs7824557 0.527 rs2572448 chr8:11239352 G/A cg21775007 chr8:11205619 TDH -0.68 -6.6 -0.51 1.08e-9 Retinal vascular caliber; TGCT cis rs9362426 0.943 rs242291 chr6:88077083 A/T cg12350822 chr6:88032061 C6orf162;GJB7 -0.45 -4.95 -0.41 2.37e-6 Depressive episodes in bipolar disorder; TGCT cis rs2688608 0.620 rs7076525 chr10:75512797 C/T cg04320760 chr10:75533139 FUT11 -0.36 -5.66 -0.45 9.83e-8 Inflammatory bowel disease; TGCT cis rs79387448 0.655 rs79091585 chr2:102917243 C/T cg09003973 chr2:102972529 NA 1.34 8.26 0.6 1.89e-13 Gut microbiota (bacterial taxa); TGCT cis rs9435341 0.896 rs1730850 chr1:107597988 C/T cg09367891 chr1:107599246 PRMT6 -0.64 -5.58 -0.45 1.43e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg19626725 chr5:178986131 RUFY1 0.46 5.76 0.46 6.14e-8 Lung cancer; TGCT cis rs7584330 0.737 rs937392 chr2:238367130 C/T cg14458575 chr2:238380390 NA 0.51 8.14 0.59 3.53e-13 Prostate cancer; TGCT cis rs3812049 0.826 rs34576922 chr5:127364103 C/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.6 -5.5 -0.44 2.11e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs7917772 0.629 rs1475646 chr10:104522564 G/T cg05855489 chr10:104503620 C10orf26 0.67 5.32 0.43 4.77e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6840360 0.554 rs4643789 chr4:152726691 C/T cg22705602 chr4:152727874 NA -0.34 -6.02 -0.48 1.87e-8 Intelligence (multi-trait analysis); TGCT cis rs7611238 0.560 rs60177727 chr3:195069337 C/T cg27323046 chr3:195102265 ACAP2 0.35 4.82 0.4 4.11e-6 Body mass index; TGCT cis rs6087990 0.735 rs2424915 chr20:31378448 C/T cg13636640 chr20:31349939 DNMT3B 0.96 12.64 0.75 4.78e-24 Ulcerative colitis; TGCT cis rs7208859 0.673 rs56085216 chr17:29217234 T/C cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs9394169 0.613 rs2395399 chr6:33777432 T/C cg00334056 chr6:33755658 LEMD2 -0.29 -5.17 -0.42 9.01e-7 Essential tremor; TGCT cis rs765787 0.530 rs12906537 chr15:45520061 T/C cg24006582 chr15:45444508 DUOX1 0.25 5.38 0.43 3.62e-7 Uric acid levels; TGCT cis rs72781680 0.678 rs56145919 chr2:24088489 A/G cg08917208 chr2:24149416 ATAD2B 0.75 4.61 0.38 9.75e-6 Lymphocyte counts; TGCT cis rs919433 0.588 rs11690163 chr2:198527507 A/T cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs854765 0.583 rs11871899 chr17:17826748 C/G cg09796270 chr17:17721594 SREBF1 0.28 5.66 0.45 9.89e-8 Total body bone mineral density; TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs6951245 1.000 rs11763020 chr7:1060288 C/T cg18402987 chr7:1209562 NA 0.66 5.39 0.44 3.36e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7786808 0.527 rs62478405 chr7:158188528 G/A cg01191920 chr7:158217561 PTPRN2 -0.37 -5.44 -0.44 2.67e-7 Obesity-related traits; TGCT cis rs67460515 0.892 rs4856703 chr3:161047720 G/T cg03342759 chr3:160939853 NMD3 -0.48 -5.16 -0.42 9.65e-7 Parkinson's disease; TGCT cis rs7119 0.604 rs2271396 chr15:77907535 C/G cg27398640 chr15:77910606 LINGO1 0.32 6.89 0.53 2.5e-10 Type 2 diabetes; TGCT cis rs10838634 1.000 rs7115038 chr11:46897792 C/G cg18332754 chr11:46939436 LRP4 -0.89 -4.77 -0.39 5.13e-6 Schizophrenia; TGCT cis rs1570884 0.556 rs2146146 chr13:50170368 C/T cg03651054 chr13:50194643 NA 0.32 5.26 0.43 6.06e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT trans rs7819412 0.807 rs4840542 chr8:10944809 G/T cg15556689 chr8:8085844 FLJ10661 -0.88 -8.75 -0.62 1.29e-14 Triglycerides; TGCT cis rs2797160 1.000 rs1739347 chr6:126014157 C/T cg05901451 chr6:126070800 HEY2 0.73 6.32 0.49 4.36e-9 Endometrial cancer; TGCT cis rs6089584 0.927 rs3787427 chr20:60579789 T/C cg16423285 chr20:60520624 NA -0.62 -6.86 -0.52 2.86e-10 Body mass index; TGCT cis rs35883536 0.528 rs1577512 chr1:101030832 G/A cg06223162 chr1:101003688 GPR88 0.43 8.41 0.6 8.23e-14 Monocyte count; TGCT cis rs12220238 1.000 rs10824075 chr10:75880254 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.73 0.57 3.14e-12 Soluble interleukin-2 receptor subunit alpha; TGCT trans rs28595532 0.668 rs58467651 chr4:119349011 T/G cg26518628 chr1:97050305 NA -0.58 -6.69 -0.51 6.71e-10 Cannabis dependence symptom count; TGCT cis rs7551222 0.750 rs898387 chr1:204579373 A/G cg09150239 chr1:204347429 NA -0.5 -5.02 -0.41 1.77e-6 Schizophrenia; TGCT cis rs35306767 0.903 rs12769431 chr10:922633 T/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs2439831 0.850 rs12442297 chr15:44168470 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.85 5.83 0.46 4.52e-8 Lung cancer in ever smokers; TGCT cis rs4285028 0.603 rs79312528 chr3:121608997 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.78 -6.72 -0.52 5.95e-10 Multiple sclerosis; TGCT cis rs12479064 0.724 rs6748200 chr2:100080895 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -4.71 -0.39 6.62e-6 Chronic sinus infection; TGCT cis rs904251 0.523 rs2776872 chr6:37482787 C/G cg01843034 chr6:37503916 NA -0.54 -7.32 -0.55 2.76e-11 Cognitive performance; TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg10862848 chr6:42927986 GNMT -0.39 -4.74 -0.39 5.72e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10782582 0.609 rs10873797 chr1:76377191 G/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.54 4.64 0.38 8.88e-6 Daytime sleep phenotypes; TGCT cis rs79976124 0.837 rs75346757 chr6:66648386 A/T cg07460842 chr6:66804631 NA 0.58 5.29 0.43 5.33e-7 Type 2 diabetes; TGCT cis rs1903068 0.925 rs1551643 chr4:55994226 T/A cg16572876 chr4:56024045 NA 0.45 5.08 0.42 1.34e-6 Endometriosis; TGCT cis rs17030434 1.000 rs732680 chr4:154725211 G/A cg14289246 chr4:154710475 SFRP2 -0.91 -7.2 -0.54 5.18e-11 Electrocardiographic conduction measures; TGCT cis rs877282 0.898 rs11253344 chr10:765162 C/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT trans rs10953454 1.000 rs34439336 chr7:104472327 G/T cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.54e-10 Obesity; TGCT cis rs514406 0.607 rs6696940 chr1:53203427 C/T cg16325326 chr1:53192061 ZYG11B -0.9 -13.18 -0.76 2.44e-25 Monocyte count; TGCT cis rs9467711 0.790 rs66488313 chr6:26631568 G/T cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs6840360 0.533 rs1397683 chr4:152715916 T/C cg17479576 chr4:152424074 FAM160A1 0.49 4.96 0.41 2.29e-6 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.744 rs11182316 chr12:38499552 G/A cg26384229 chr12:38710491 ALG10B 0.89 8.14 0.59 3.55e-13 Bladder cancer; TGCT cis rs4689388 0.890 rs6838400 chr4:6295427 C/G cg14416269 chr4:6271139 WFS1 0.37 4.85 0.4 3.58e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6840360 0.681 rs9968292 chr4:152297368 T/C cg17479576 chr4:152424074 FAM160A1 -0.54 -5.83 -0.46 4.47e-8 Intelligence (multi-trait analysis); TGCT cis rs16958440 0.867 rs74845165 chr18:44690852 T/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs7439150 0.954 rs72679202 chr4:155475566 A/T cg22130008 chr4:155548532 NA -0.43 -5.38 -0.44 3.5e-7 Fibrinogen levels; TGCT cis rs8031584 0.752 rs1852035 chr15:31184803 C/G cg08704250 chr15:31115839 NA -0.42 -6.3 -0.49 4.64e-9 Huntington's disease progression; TGCT cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg03517284 chr6:25882590 NA -0.66 -5.95 -0.47 2.55e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs4699574 chr4:98725544 C/T cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.764 rs115877991 chr4:119728298 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs12142240 0.698 rs12385696 chr1:46818836 A/G cg14993813 chr1:46806288 NSUN4 -0.56 -4.72 -0.39 6.36e-6 Menopause (age at onset); TGCT cis rs514406 0.607 rs1930305 chr1:53195481 G/T cg22166914 chr1:53195759 ZYG11B -0.5 -9.42 -0.65 3.19e-16 Monocyte count; TGCT cis rs3617 0.573 rs4687682 chr3:52916939 T/C cg11645453 chr3:52864694 ITIH4 -0.26 -5.07 -0.41 1.39e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg23205692 chr1:25664452 TMEM50A 0.5 5.21 0.42 7.56e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs2019216 0.521 rs10871487 chr17:21939193 G/A cg22648282 chr17:21454238 C17orf51 -0.58 -5.59 -0.45 1.36e-7 Pelvic organ prolapse; TGCT cis rs12049351 0.774 rs12022203 chr1:229658797 C/T cg12130225 chr1:229698885 NA 0.38 4.59 0.38 1.09e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs9447004 0.583 rs28360541 chr6:74432427 T/G cg23004174 chr6:74404879 CD109 0.23 5.08 0.42 1.35e-6 Blood protein levels;Calcium levels; TGCT cis rs2933343 0.621 rs789242 chr3:128585707 T/C cg11901034 chr3:128598214 ACAD9 -0.62 -6.1 -0.48 1.26e-8 IgG glycosylation; TGCT cis rs73198271 0.740 rs10113326 chr8:8647630 A/T cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2404602 0.583 rs12438741 chr15:76542114 C/A cg26408565 chr15:76604113 ETFA -0.46 -6.46 -0.5 2.15e-9 Blood metabolite levels; TGCT cis rs782590 0.557 rs7592219 chr2:55887176 T/C cg18811423 chr2:55921094 PNPT1 -0.61 -5.3 -0.43 5.2e-7 Metabolic syndrome; TGCT cis rs2439831 1.000 rs689826 chr15:43749916 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.18 0.59 2.83e-13 Lung cancer in ever smokers; TGCT cis rs7523273 0.606 rs2724391 chr1:207953244 T/C cg22525895 chr1:207977042 MIR29B2 0.55 9.54 0.65 1.67e-16 Schizophrenia; TGCT cis rs77216612 0.835 rs56692845 chr12:12887811 C/T cg09462578 chr12:12878428 APOLD1 -1.0 -8.3 -0.6 1.5e-13 Lymphocyte counts; TGCT cis rs8084125 0.832 rs62105180 chr18:74951197 C/G cg15443732 chr18:74961078 GALR1 0.48 4.7 0.39 6.76e-6 Obesity-related traits; TGCT cis rs5769707 0.609 rs739247 chr22:49996657 T/C cg06623630 chr22:50017776 C22orf34 -0.26 -4.44 -0.37 1.97e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1799949 1.000 rs2298862 chr17:41176688 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs700590 0.723 rs700588 chr5:88108574 G/A cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.24e-7 Educational attainment (years of education); TGCT cis rs1862618 0.853 rs252909 chr5:56121131 T/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs2228479 0.850 rs1800355 chr16:89813194 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs56104184 1.000 rs56104184 chr19:49370310 C/T cg17863274 chr19:49399704 TULP2 -0.36 -5.18 -0.42 8.68e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs5769707 0.935 rs9616332 chr22:50047678 C/G cg05373962 chr22:49881684 NA -0.3 -6.19 -0.49 8.22e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10493389 0.673 rs7553999 chr1:66290125 C/G cg08716655 chr1:66257732 PDE4B -0.41 -4.54 -0.38 1.29e-5 Echocardiographic traits; TGCT cis rs8017423 0.630 rs4900038 chr14:90821677 A/G cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs72615157 0.697 rs2056726 chr7:99780283 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.66 5.08 0.42 1.33e-6 Lung function (FEV1/FVC); TGCT cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg08280861 chr8:58055591 NA 0.48 5.29 0.43 5.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7777754 0.512 rs11238131 chr7:50538589 T/C cg18232548 chr7:50535776 DDC -0.39 -6.01 -0.47 1.91e-8 Response to zileuton treatment in asthma (FEV1 change interaction); TGCT cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs79349575 0.783 rs12602933 chr17:47029280 G/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs4722166 0.508 rs1474347 chr7:22768124 A/C cg13104385 chr7:22767384 IL6 -0.21 -4.46 -0.37 1.79e-5 Lung cancer; TGCT cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg20887711 chr4:1340912 KIAA1530 -0.88 -7.99 -0.58 7.85e-13 Longevity; TGCT cis rs10465746 0.775 rs4907186 chr1:84340753 G/T cg10977910 chr1:84465055 TTLL7 0.68 6.7 0.52 6.46e-10 Obesity-related traits; TGCT cis rs2836974 0.533 rs4817999 chr21:40554355 C/A cg11644478 chr21:40555479 PSMG1 -0.63 -5.83 -0.46 4.45e-8 Cognitive function; TGCT cis rs2549003 1.000 rs2070727 chr5:131820275 C/A cg21138405 chr5:131827807 IRF1 0.19 4.79 0.4 4.64e-6 Asthma (sex interaction); TGCT cis rs7017914 0.870 rs3110256 chr8:71938136 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs9796 0.870 rs12905926 chr15:41283408 G/A cg18705301 chr15:41695430 NDUFAF1 0.43 5.52 0.44 1.9e-7 Menopause (age at onset); TGCT cis rs1056107 0.898 rs1417111 chr9:114991313 A/T cg02332936 chr9:115140584 NA -0.25 -4.45 -0.37 1.89e-5 Colorectal cancer; TGCT cis rs9733 0.536 rs6661415 chr1:150635869 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs6570726 0.791 rs10457788 chr6:145921136 T/A cg05347473 chr6:146136440 FBXO30 0.53 4.92 0.4 2.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs853679 0.546 rs200990 chr6:27815823 T/G cg10876282 chr6:28092338 ZSCAN16 0.74 4.44 0.37 1.98e-5 Depression; TGCT cis rs13177918 0.750 rs58256223 chr5:149822019 T/A cg14059543 chr5:149831962 NA -0.7 -9.26 -0.64 7.92e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg04389838 chr3:44770851 ZNF501 -0.41 -5.7 -0.46 8.29e-8 Depressive symptoms; TGCT cis rs2243480 1.000 rs313814 chr7:65503293 C/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs6848397 chr4:98946738 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs57590327 0.528 rs4856346 chr3:81502655 T/G cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs4665809 1.000 rs6729080 chr2:26301282 G/A cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg21951975 chr1:209979733 IRF6 0.66 5.69 0.45 8.77e-8 Cleft lip with or without cleft palate; TGCT cis rs9457247 0.935 rs427824 chr6:167403918 T/G cg23791538 chr6:167370224 RNASET2 -0.52 -5.16 -0.42 9.46e-7 Crohn's disease; TGCT cis rs922182 1.000 rs62021495 chr15:64275409 C/T cg02919090 chr15:64263738 DAPK2 0.29 5.46 0.44 2.47e-7 Blood protein levels; TGCT cis rs11190604 1.000 rs17113137 chr10:102241998 G/C cg16342193 chr10:102329863 NA -0.4 -5.35 -0.43 4.1e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7772486 0.790 rs3924498 chr6:146233338 A/T cg23711669 chr6:146136114 FBXO30 -0.89 -10.38 -0.68 1.54e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs11190604 0.767 rs3829162 chr10:102172752 T/G cg16005271 chr10:102321736 NA 0.45 4.57 0.38 1.15e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs17076896 0.786 rs7331051 chr13:19934191 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs3749237 0.595 rs1050088 chr3:49570882 C/T cg07636037 chr3:49044803 WDR6 -0.62 -5.86 -0.47 3.89e-8 Resting heart rate; TGCT cis rs7542091 0.704 rs9429825 chr1:210052133 C/G cg22029157 chr1:209979665 IRF6 0.64 6.17 0.48 8.82e-9 Monobrow; TGCT cis rs9807989 0.507 rs4851004 chr2:103009537 A/G cg03938978 chr2:103052716 IL18RAP -0.27 -5.41 -0.44 3.17e-7 Asthma; TGCT trans rs2760061 0.819 rs708120 chr1:228207651 G/C cg16006296 chr10:38738647 LOC399744 -0.31 -7.12 -0.54 7.75e-11 Diastolic blood pressure; TGCT cis rs208515 0.525 rs1484577 chr6:66688397 A/G cg07460842 chr6:66804631 NA 0.87 9.16 0.64 1.32e-15 Exhaled nitric oxide levels; TGCT cis rs68170813 0.559 rs75723759 chr7:106962407 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs7412746 0.658 rs10305714 chr1:150800655 C/T cg09365446 chr1:150670422 GOLPH3L -0.34 -4.99 -0.41 1.99e-6 Melanoma; TGCT cis rs10791097 0.694 rs2155750 chr11:130751261 A/C cg05962950 chr11:130786565 SNX19 0.91 11.68 0.72 1.01e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2760061 0.819 rs708115 chr1:228198046 C/T cg02753203 chr1:228287806 NA 0.31 5.94 0.47 2.62e-8 Diastolic blood pressure; TGCT cis rs739496 0.843 rs638791 chr12:111989236 A/G cg10833066 chr12:111807467 FAM109A 0.37 4.96 0.41 2.31e-6 Platelet count; TGCT cis rs6671200 0.920 rs35403759 chr1:95702890 C/T cg03123541 chr1:95699097 RWDD3 0.91 6.4 0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs1322512 0.959 rs1727053 chr6:152947596 A/G cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs6545883 0.929 rs7561229 chr2:61737990 A/T cg15711740 chr2:61764176 XPO1 -0.56 -5.17 -0.42 9.02e-7 Tuberculosis; TGCT cis rs2243480 1.000 rs427044 chr7:65508545 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs12257961 0.579 rs10737095 chr10:15382547 C/G cg10616319 chr10:15468812 NA -0.25 -4.66 -0.39 8.15e-6 Selective IgA deficiency; TGCT cis rs921968 0.608 rs495855 chr2:219357858 A/G cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs4918072 0.667 rs10430666 chr10:105702425 T/C cg11005552 chr10:105648138 OBFC1 0.33 4.67 0.39 7.56e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs13111977 chr4:98953813 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10795061 0.576 rs6601744 chr10:3711563 C/A cg13668419 chr10:3197757 PITRM1 -0.19 -5.32 -0.43 4.62e-7 Subjective well-being; TGCT cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs611744 0.550 rs1448154 chr8:109281053 T/C cg21045802 chr8:109455806 TTC35 0.72 7.43 0.56 1.53e-11 Dupuytren's disease; TGCT cis rs1153858 0.723 rs11855527 chr15:45606685 G/A cg14582100 chr15:45693742 SPATA5L1 -0.45 -4.97 -0.41 2.17e-6 Homoarginine levels; TGCT cis rs6088590 0.561 rs6088528 chr20:33156742 G/A cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs1113500 0.814 rs893983 chr1:108630338 C/T cg22161131 chr1:109420278 GPSM2 -0.49 -4.54 -0.38 1.34e-5 Growth-regulated protein alpha levels; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg14820908 chr5:178986412 RUFY1 -0.6 -6.69 -0.51 7.01e-10 Lung cancer; TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs734999 0.545 rs6684865 chr1:2546229 A/G cg18854424 chr1:2615690 NA -0.43 -4.96 -0.41 2.23e-6 Ulcerative colitis; TGCT cis rs10927875 0.518 rs1763604 chr1:16339772 C/G cg22431228 chr1:16359049 CLCNKA -0.28 -5.81 -0.46 4.9e-8 Dilated cardiomyopathy; TGCT cis rs1949733 0.656 rs6845969 chr4:8402465 A/T cg11789530 chr4:8429930 ACOX3 0.51 4.75 0.39 5.45e-6 Response to antineoplastic agents; TGCT cis rs77741769 0.549 rs57697145 chr12:121333552 T/G cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.56e-5 Mean corpuscular volume; TGCT cis rs7666738 0.753 rs1830230 chr4:99026186 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12900413 0.562 rs11631438 chr15:90300620 C/T cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2997447 0.688 rs17257100 chr1:26439586 C/T cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs270601 0.770 rs932019 chr5:131599370 T/C cg12564285 chr5:131593104 PDLIM4 0.4 4.77 0.39 5.18e-6 Acylcarnitine levels; TGCT cis rs7552404 0.696 rs12140121 chr1:76455001 A/G cg22875332 chr1:76189707 ACADM 0.64 5.79 0.46 5.47e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9389248 0.690 rs6939543 chr6:135255143 A/G cg22676075 chr6:135203613 NA -0.5 -5.04 -0.41 1.59e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs1799949 1.000 rs2175957 chr17:41286822 T/G cg10047753 chr17:41438598 NA 0.97 9.66 0.66 8.66e-17 Menopause (age at onset); TGCT cis rs5750830 0.546 rs4821891 chr22:39785381 C/T cg02038168 chr22:39784481 NA -0.72 -6.06 -0.48 1.55e-8 Intelligence (multi-trait analysis); TGCT cis rs6074578 0.621 rs6086355 chr20:140853 C/G cg16931068 chr20:139680 DEFB127 0.26 4.5 0.37 1.52e-5 Hirschsprung disease; TGCT cis rs7131987 0.903 rs1991114 chr12:29392082 G/T cg09582351 chr12:29534625 ERGIC2 -0.24 -4.53 -0.38 1.35e-5 QT interval; TGCT cis rs11096990 0.552 rs7655170 chr4:39173604 T/G cg20847110 chr4:39482781 LOC401127 0.17 4.96 0.41 2.3e-6 Cognitive function; TGCT cis rs7017914 0.902 rs1373480 chr8:71686967 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs514406 0.893 rs476108 chr1:53317351 C/T cg24675658 chr1:53192096 ZYG11B -0.71 -8.23 -0.59 2.14e-13 Monocyte count; TGCT cis rs35883536 0.647 rs2647325 chr1:101040195 T/C cg10298815 chr1:101004474 GPR88 0.24 4.47 0.37 1.76e-5 Monocyte count; TGCT cis rs9859260 0.710 rs366268 chr3:195782177 A/G cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs916888 0.779 rs199498 chr17:44865603 A/G cg15921436 chr17:44337874 NA 0.38 5.06 0.41 1.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 1.000 rs66796009 chr8:58174529 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1552244 0.832 rs73024591 chr3:10203194 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.55 -6.55 -0.51 1.38e-9 Alzheimer's disease; TGCT cis rs8177253 0.665 rs4525863 chr3:133436136 C/A cg16414030 chr3:133502952 NA -0.5 -6.87 -0.52 2.81e-10 Iron status biomarkers; TGCT cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.95 9.68 0.66 7.34e-17 Intelligence (multi-trait analysis); TGCT cis rs7681440 1.000 rs7681440 chr4:90756550 C/G cg20003494 chr4:90757398 SNCA 0.53 4.94 0.41 2.45e-6 Dementia with Lewy bodies; TGCT cis rs1609391 0.543 rs2117009 chr3:136633571 A/T cg15507776 chr3:136538369 TMEM22 -0.65 -6.73 -0.52 5.6e-10 Neuroticism; TGCT cis rs6569992 0.636 rs55683605 chr6:135487107 C/T cg22676075 chr6:135203613 NA 0.73 4.97 0.41 2.13e-6 Red blood cell traits; TGCT cis rs13191362 0.935 rs7769048 chr6:163010040 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4654899 0.604 rs12031023 chr1:21148839 A/G cg01072550 chr1:21505969 NA 0.55 8.83 0.62 8.24e-15 Superior frontal gyrus grey matter volume; TGCT cis rs4822044 0.560 rs7284839 chr22:42010902 C/T cg17554472 chr22:41940697 POLR3H 0.5 5.35 0.43 4.07e-7 Cannabis dependence symptom count; TGCT cis rs2549003 0.933 rs7719499 chr5:131814091 C/G cg21138405 chr5:131827807 IRF1 0.19 4.64 0.38 8.71e-6 Asthma (sex interaction); TGCT cis rs9393692 0.905 rs9357004 chr6:26303319 A/G cg00631329 chr6:26305371 NA -0.41 -5.87 -0.47 3.81e-8 Educational attainment; TGCT cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Vitiligo; TGCT cis rs4919694 0.615 rs78384860 chr10:105003019 G/T cg04362960 chr10:104952993 NT5C2 1.03 6.7 0.52 6.55e-10 Arsenic metabolism; TGCT cis rs595982 0.517 rs10404905 chr19:49406175 A/T cg15549821 chr19:49342101 PLEKHA4 0.43 5.88 0.47 3.63e-8 Red cell distribution width; TGCT cis rs7973719 0.966 rs1450962 chr12:7320545 A/G cg07052231 chr12:7363540 PEX5 0.34 5.17 0.42 8.99e-7 IgG glycosylation; TGCT cis rs2439831 0.571 rs2470121 chr15:43937618 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.61 0.51 1.03e-9 Lung cancer in ever smokers; TGCT cis rs6912958 0.781 rs9450755 chr6:88303702 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.57 -5.22 -0.42 7.36e-7 Monocyte percentage of white cells; TGCT cis rs2842992 0.789 rs9364536 chr6:160225559 G/C cg11366901 chr6:160182831 ACAT2 1.03 6.98 0.53 1.59e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs3796352 1.000 rs34979715 chr3:53048960 G/A cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs732765 0.734 rs2270425 chr14:75179734 C/G cg06637938 chr14:75390232 RPS6KL1 -0.57 -5.03 -0.41 1.69e-6 Non-small cell lung cancer; TGCT cis rs9811920 0.809 rs6802817 chr3:99779264 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.44 4.94 0.41 2.48e-6 Axial length; TGCT cis rs9677476 0.516 rs3769989 chr2:232011440 C/A cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs909002 0.886 rs10798880 chr1:32097088 G/T cg11573219 chr1:32083031 HCRTR1 -0.48 -6.35 -0.5 3.65e-9 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs9650139 chr8:58190508 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7618915 0.570 rs11130319 chr3:52755592 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.9 0.47 3.2e-8 Bipolar disorder; TGCT cis rs10751667 0.961 rs7943115 chr11:973885 T/C cg06064525 chr11:970664 AP2A2 -0.31 -6.25 -0.49 5.89e-9 Alzheimer's disease (late onset); TGCT cis rs826838 0.933 rs980573 chr12:39127811 T/C cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs6860806 0.507 rs272882 chr5:131669161 G/T cg24060327 chr5:131705240 SLC22A5 -0.76 -8.4 -0.6 8.54e-14 Breast cancer; TGCT cis rs597539 0.652 rs604524 chr11:68629929 G/A cg04772025 chr11:68637568 NA 0.59 6.67 0.51 7.71e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12188164 0.965 rs11745789 chr5:450777 T/C cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs904251 1.000 rs10947673 chr6:37445079 C/T cg08126542 chr6:37504118 NA -0.4 -5.27 -0.43 5.92e-7 Cognitive performance; TGCT cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg09436375 chr6:42928200 GNMT -0.4 -5.2 -0.42 8.08e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6089584 0.888 rs2892060 chr20:60617955 G/T cg13770153 chr20:60521292 NA -0.54 -7.13 -0.54 7.45e-11 Body mass index; TGCT cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg02725872 chr8:58115012 NA -0.43 -5.35 -0.43 4.11e-7 Developmental language disorder (linguistic errors); TGCT cis rs858239 0.863 rs274054 chr7:23390467 G/C cg05602783 chr7:23145260 KLHL7 -0.56 -4.58 -0.38 1.13e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs7772486 0.790 rs2254288 chr6:146204470 G/A cg23711669 chr6:146136114 FBXO30 0.87 9.99 0.67 1.32e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs3780486 0.718 rs10971418 chr9:33122024 A/C cg20290983 chr6:43655470 MRPS18A -1.0 -7.29 -0.55 3.19e-11 IgG glycosylation; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg07157834 chr1:205819609 PM20D1 0.45 7.45 0.56 1.35e-11 Menarche (age at onset); TGCT cis rs6089584 0.819 rs1467593 chr20:60601432 T/G cg13770153 chr20:60521292 NA 0.52 6.68 0.51 7.32e-10 Body mass index; TGCT cis rs7666738 0.609 rs35214820 chr4:98864692 G/A cg17366294 chr4:99064904 C4orf37 0.67 6.02 0.48 1.86e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs916888 0.697 rs199516 chr17:44856485 C/T cg07870213 chr5:140052090 DND1 -0.61 -7.32 -0.55 2.7e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs514406 0.565 rs897732 chr1:53382816 A/C cg27535305 chr1:53392650 SCP2 -0.29 -6.13 -0.48 1.08e-8 Monocyte count; TGCT cis rs17712049 0.908 rs62447150 chr7:48199634 G/C cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs1023500 1.000 rs1023499 chr22:42340582 T/C cg04692870 chr22:42525206 CYP2D6 -0.33 -5.0 -0.41 1.9e-6 Schizophrenia; TGCT cis rs3087591 0.659 rs8065496 chr17:29720140 T/C cg24425628 chr17:29625626 OMG;NF1 0.38 5.5 0.44 2.09e-7 Hip circumference; TGCT trans rs6089829 0.888 rs4809467 chr20:61671688 A/G cg13615516 chr5:77269221 NA 0.73 8.39 0.6 9.12e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs4820539 1.000 rs5759595 chr22:23471624 G/A cg14186256 chr22:23484241 RTDR1 0.99 12.58 0.75 6.81e-24 Bone mineral density; TGCT cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs10504229 0.861 rs57942497 chr8:58171239 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9393777 0.588 rs11967935 chr6:26560672 A/C cg15659132 chr6:26577336 NA -0.76 -5.72 -0.46 7.53e-8 Intelligence (multi-trait analysis); TGCT cis rs9372498 0.536 rs62422189 chr6:118907053 C/T cg07617317 chr6:118971624 C6orf204 0.52 5.43 0.44 2.85e-7 Diastolic blood pressure; TGCT cis rs6534347 0.551 rs925549 chr4:123530993 A/G cg10583651 chr4:123538969 IL21 0.32 4.79 0.4 4.59e-6 Type 1 diabetes; TGCT cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs453301 0.507 rs2929306 chr8:9084909 C/T cg15556689 chr8:8085844 FLJ10661 -0.65 -6.15 -0.48 9.69e-9 Joint mobility (Beighton score); TGCT cis rs1129187 0.702 rs2395943 chr6:42940673 A/G cg09436375 chr6:42928200 GNMT -0.41 -5.19 -0.42 8.34e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs986417 0.818 rs12883272 chr14:61015153 A/G cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs1801251 0.752 rs2592126 chr2:233751377 A/G cg25237894 chr2:233734115 C2orf82 -0.31 -5.98 -0.47 2.2e-8 Coronary artery disease; TGCT cis rs11719291 0.831 rs11715177 chr3:48763894 G/A cg00383909 chr3:49044727 WDR6 1.24 6.68 0.51 7.21e-10 Cognitive function; TGCT cis rs7666738 0.830 rs6833822 chr4:98951354 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12780845 0.540 rs11254413 chr10:17204187 G/A cg01003015 chr10:17271136 VIM 0.58 5.18 0.42 8.62e-7 Homocysteine levels; TGCT cis rs3091242 1.000 rs9689 chr1:25688276 A/G cg09222892 chr1:25734099 RHCE -0.43 -6.98 -0.53 1.6e-10 Erythrocyte sedimentation rate; TGCT cis rs4689388 0.581 rs4688985 chr4:6285715 A/G cg25554036 chr4:6271136 WFS1 0.56 6.72 0.52 5.99e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7647973 1.000 rs1464569 chr3:49460350 A/G cg07690219 chr3:49449608 TCTA;RHOA -0.53 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs6964587 1.000 rs10234434 chr7:91673308 A/T cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs1215050 0.755 rs6851840 chr4:98776366 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs765787 0.530 rs4775834 chr15:45537511 C/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs2836974 0.897 rs36113648 chr21:40555497 G/A cg06238570 chr21:40685208 BRWD1 0.76 7.13 0.54 7.21e-11 Cognitive function; TGCT cis rs4862750 0.872 rs13143414 chr4:187878213 G/A cg11301795 chr4:187892539 NA -0.33 -5.05 -0.41 1.51e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs7178572 0.568 rs12443386 chr15:77491389 C/T cg15453836 chr15:77711506 NA 0.45 5.01 0.41 1.81e-6 Type 2 diabetes; TGCT cis rs10256972 0.721 rs10435145 chr7:1065988 C/T cg18402987 chr7:1209562 NA 0.4 4.87 0.4 3.39e-6 Longevity;Endometriosis; TGCT cis rs711245 0.572 rs3821150 chr2:36795233 G/A cg09467607 chr2:36825704 FEZ2 0.39 5.32 0.43 4.58e-7 Height; TGCT cis rs28785552 0.589 rs11669056 chr19:53244443 G/A cg22067481 chr19:53234126 ZNF611 -0.45 -6.38 -0.5 3.23e-9 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7149242 0.500 rs10144381 chr14:101173297 C/T cg18089426 chr14:101175970 NA 0.44 4.98 0.41 2.09e-6 Platelet count; TGCT cis rs2243480 1.000 rs35283677 chr7:65359233 C/T cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT cis rs6088580 0.602 rs6058064 chr20:33086622 A/G cg08999081 chr20:33150536 PIGU 0.28 5.51 0.44 1.94e-7 Glomerular filtration rate (creatinine); TGCT cis rs13108904 0.557 rs1680033 chr4:1243404 C/T cg20887711 chr4:1340912 KIAA1530 -0.7 -6.37 -0.5 3.4e-9 Obesity-related traits; TGCT cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg03188948 chr7:1209495 NA 0.65 5.45 0.44 2.59e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3806843 1.000 rs1548701 chr5:140164557 T/C cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs1857353 1.000 rs983331 chr1:75880565 C/G cg11838876 chr1:75668600 SLC44A5 -0.53 -4.89 -0.4 3.11e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs3796352 1.000 rs36090694 chr3:53010742 T/C cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2282802 0.685 rs35214989 chr5:139636127 T/C cg01081189 chr5:139537190 NA 0.29 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg03188948 chr7:1209495 NA 0.68 5.75 0.46 6.65e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.830 rs6819047 chr4:98866902 G/A cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6459788 0.692 rs10807645 chr7:157258979 T/C cg04274827 chr7:157277617 NA 0.3 5.47 0.44 2.42e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs1862618 0.613 rs252889 chr5:56227069 C/A cg20203395 chr5:56204925 C5orf35 -0.53 -4.92 -0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs3733585 0.605 rs4235354 chr4:10122942 C/A cg11266682 chr4:10021025 SLC2A9 -0.56 -6.45 -0.5 2.28e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3784262 0.765 rs11631127 chr15:58270009 G/C cg12031962 chr15:58353849 ALDH1A2 -0.41 -5.94 -0.47 2.71e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs700590 0.603 rs160045 chr5:88140942 G/A cg22951263 chr5:87985283 NA 0.63 5.8 0.46 5.25e-8 Educational attainment (years of education); TGCT cis rs10131894 0.611 rs175001 chr14:75436452 A/C cg06637938 chr14:75390232 RPS6KL1 0.52 4.49 0.37 1.64e-5 Coronary artery disease; TGCT cis rs3806843 0.864 rs2531343 chr5:140129346 A/G cg19875535 chr5:140030758 IK -0.35 -5.97 -0.47 2.27e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7582180 0.629 rs74177696 chr2:100938481 C/G cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.89e-6 Intelligence (multi-trait analysis); TGCT cis rs2469997 1.000 rs2447165 chr8:120371318 G/A cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs4742903 0.933 rs10820608 chr9:106890840 A/G cg21169611 chr9:106856078 SMC2 0.51 4.84 0.4 3.81e-6 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg06634786 chr22:41940651 POLR3H 0.95 8.71 0.62 1.61e-14 Vitiligo; TGCT cis rs73058052 0.597 rs7254718 chr19:50073226 A/G cg14048834 chr19:49990801 RPL13AP5;RPL13A -0.52 -4.63 -0.38 9.23e-6 Fibrinogen levels; TGCT cis rs9859260 0.744 rs406271 chr3:195776976 T/C cg02975922 chr3:195473998 MUC4 0.25 5.1 0.42 1.24e-6 Mean corpuscular volume; TGCT cis rs7833790 0.724 rs1054078 chr8:82712153 A/G cg17211192 chr8:82754475 SNX16 -0.95 -8.83 -0.62 8.45e-15 Diastolic blood pressure; TGCT trans rs4332037 0.539 rs1533827 chr7:2074290 A/G cg25206134 chr2:45395956 NA -0.91 -7.01 -0.53 1.32e-10 Bipolar disorder; TGCT cis rs7937840 0.581 rs4963462 chr11:61886672 A/T cg05871569 chr11:61891931 INCENP -0.67 -6.16 -0.48 9.49e-9 Breast cancer; TGCT cis rs709400 0.628 rs11621510 chr14:103869620 T/C cg26031613 chr14:104095156 KLC1 0.85 9.32 0.64 5.54e-16 Body mass index; TGCT cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2576037 0.583 rs545344 chr18:44367079 A/G cg23302884 chr18:44338147 ST8SIA5 -0.43 -4.96 -0.41 2.26e-6 Personality dimensions; TGCT cis rs4808199 0.948 rs1859287 chr19:19422187 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.64 4.75 0.39 5.58e-6 Nonalcoholic fatty liver disease; TGCT cis rs4523957 0.651 rs4790315 chr17:2070529 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs66561647 0.929 rs67423398 chr8:128972220 C/T cg11792826 chr8:129160931 MIR1208 0.21 4.89 0.4 3.02e-6 Hemoglobin concentration; TGCT cis rs9527 1.000 rs4919690 chr10:104616500 C/T cg04362960 chr10:104952993 NT5C2 -0.62 -5.18 -0.42 8.61e-7 Arsenic metabolism; TGCT cis rs813218 0.527 rs793450 chr3:99532532 C/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.46 5.27 0.43 5.89e-7 Orofacial clefts; TGCT cis rs76878669 0.561 rs7105015 chr11:66159390 A/G cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.82e-9 Educational attainment (years of education); TGCT cis rs832540 0.931 rs1466008 chr5:56213406 G/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.18 -0.42 8.65e-7 Coronary artery disease; TGCT trans rs6089829 0.962 rs2872543 chr20:61665017 G/A cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9902453 0.967 rs1906450 chr17:28515744 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.43 0.5 2.49e-9 Coffee consumption (cups per day); TGCT cis rs4919669 0.668 rs10786701 chr10:104412308 C/T cg05855489 chr10:104503620 C10orf26 0.8 4.7 0.39 6.8e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs56104184 0.775 rs56317021 chr19:49395960 C/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs10782582 0.609 rs1770889 chr1:76401166 A/G cg10523679 chr1:76189770 ACADM -0.58 -5.21 -0.42 7.7e-7 Daytime sleep phenotypes; TGCT cis rs3733589 0.744 rs57897925 chr4:10053281 G/A cg02734326 chr4:10020555 SLC2A9 -0.99 -4.48 -0.37 1.7e-5 Renal overload gout; TGCT cis rs7914558 1.000 rs7071373 chr10:104771922 A/G cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.34e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1005277 0.579 rs1780115 chr10:38524773 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs11167764 1.000 rs6887599 chr5:141484349 G/A cg08523384 chr5:141488047 NDFIP1 -0.25 -5.32 -0.43 4.72e-7 Crohn's disease; TGCT cis rs9372498 0.536 rs62422189 chr6:118907053 C/T cg21191810 chr6:118973309 C6orf204 -0.4 -5.12 -0.42 1.12e-6 Diastolic blood pressure; TGCT cis rs10501293 0.956 rs10768918 chr11:43134481 C/T cg03447554 chr11:43094025 NA -0.48 -6.72 -0.52 5.89e-10 Cognitive performance; TGCT cis rs79349575 0.783 rs12602746 chr17:47031741 A/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs9467773 0.933 rs35355150 chr6:26526039 G/A cg26531700 chr6:26746687 NA 0.55 5.57 0.45 1.53e-7 Intelligence (multi-trait analysis); TGCT cis rs2797160 1.000 rs1832938 chr6:125988964 G/C cg05901451 chr6:126070800 HEY2 -0.74 -6.47 -0.5 2.1e-9 Endometrial cancer; TGCT cis rs2439831 1.000 rs2253708 chr15:43797273 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.82 5.71 0.46 7.85e-8 Lung cancer in ever smokers; TGCT cis rs9303401 0.614 rs66480139 chr17:57101538 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.82 0.46 4.8e-8 Cognitive test performance; TGCT cis rs6570726 0.967 rs365515 chr6:145802833 C/T cg23711669 chr6:146136114 FBXO30 -0.65 -5.87 -0.47 3.65e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.47 0.56 1.26e-11 Platelet count; TGCT cis rs10927875 0.541 rs1763601 chr1:16340460 G/T cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs4563143 0.634 rs113736470 chr19:29240125 G/A cg14983838 chr19:29218262 NA 0.75 6.87 0.53 2.69e-10 Methadone dose in opioid dependence; TGCT cis rs17221829 0.574 rs7930964 chr11:89377313 A/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.13e-6 Anxiety in major depressive disorder; TGCT cis rs2236918 0.687 rs2797600 chr1:242029331 C/T cg04158730 chr1:242011433 EXO1 0.56 5.2 0.42 8.05e-7 Menopause (age at onset); TGCT cis rs3748682 0.861 rs28411034 chr1:38276997 G/A cg04496824 chr1:38276835 MTF1 0.21 4.61 0.38 1.01e-5 Hypothyroidism; TGCT cis rs13242816 0.881 rs56034786 chr7:116106360 T/C cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs877282 0.947 rs7923867 chr10:768094 G/A cg17470449 chr10:769945 NA 0.34 5.13 0.42 1.1e-6 Uric acid levels; TGCT cis rs1669338 0.588 rs3864049 chr3:3186719 T/G cg16797762 chr3:3221439 CRBN -0.89 -5.7 -0.46 8.2e-8 White matter integrity; TGCT cis rs614226 0.938 rs7963543 chr12:120923948 C/A cg10072921 chr12:121022843 NA -0.42 -4.65 -0.39 8.28e-6 Type 1 diabetes nephropathy; TGCT cis rs78456975 1.000 rs28742145 chr2:1562671 T/C cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs62064224 0.791 rs11656289 chr17:30761160 T/C cg18200150 chr17:30822561 MYO1D 0.6 8.46 0.6 6.37e-14 Schizophrenia; TGCT cis rs11098499 0.618 rs28491261 chr4:120294900 C/A cg09307838 chr4:120376055 NA 0.66 6.45 0.5 2.22e-9 Corneal astigmatism; TGCT cis rs1670533 0.872 rs13108222 chr4:1054256 C/A cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs8030485 0.536 rs1915724 chr15:79441027 A/G cg17916960 chr15:79447300 NA 0.4 6.21 0.49 7.4e-9 Left ventricle wall thickness; TGCT cis rs7586879 0.616 rs10203386 chr2:25136866 T/A cg15423357 chr2:25149977 NA 0.5 4.98 0.41 2.11e-6 Body mass index; TGCT cis rs6882046 0.513 rs446219 chr5:88005827 T/C cg22951263 chr5:87985283 NA -0.58 -6.22 -0.49 6.92e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs853679 0.517 rs9393896 chr6:28127703 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs10504229 0.953 rs114853497 chr8:58176176 A/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs889312 0.500 rs185219 chr5:56136492 A/G cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs2688608 0.592 rs12253429 chr10:75496161 C/G cg15838173 chr10:75533400 FUT11 -0.31 -5.02 -0.41 1.73e-6 Inflammatory bowel disease; TGCT cis rs6089584 0.526 rs6089619 chr20:60610916 C/T cg06108461 chr20:60628389 TAF4 -0.42 -5.27 -0.43 5.89e-7 Body mass index; TGCT cis rs875971 0.522 rs2008188 chr7:65429013 G/C cg18876405 chr7:65276391 NA 0.38 5.89 0.47 3.4e-8 Aortic root size; TGCT cis rs9926296 0.562 rs4785725 chr16:89893243 A/G cg27121462 chr16:89883253 FANCA 0.53 4.94 0.41 2.48e-6 Vitiligo; TGCT cis rs4268898 0.722 rs11680491 chr2:24416292 T/A cg02683114 chr2:24398427 C2orf84 0.2 4.86 0.4 3.41e-6 Asthma; TGCT cis rs9581857 0.725 rs9319366 chr13:28017722 C/T cg22138327 chr13:27999177 GTF3A 0.77 5.47 0.44 2.33e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs3015497 0.594 rs35637875 chr14:51132533 T/G cg04730355 chr14:51134070 SAV1 -0.62 -6.07 -0.48 1.46e-8 Mean platelet volume; TGCT cis rs6500602 0.964 rs62039173 chr16:4463846 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.31 5.19 0.42 8.4e-7 Schizophrenia; TGCT cis rs9517302 0.615 rs9517306 chr13:99097962 T/C cg22223119 chr13:99095684 FARP1 -0.61 -6.61 -0.51 1.01e-9 Obesity-related traits; TGCT cis rs7412746 0.658 rs3768016 chr1:150809919 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.69 0.39 7.01e-6 Melanoma; TGCT cis rs372883 0.600 rs2832298 chr21:30743863 C/G cg24692254 chr21:30365293 RNF160 0.51 4.55 0.38 1.25e-5 Pancreatic cancer; TGCT cis rs6840360 0.573 rs4696257 chr4:152291689 A/G cg17479576 chr4:152424074 FAM160A1 -0.45 -4.77 -0.39 5.06e-6 Intelligence (multi-trait analysis); TGCT cis rs9616064 0.670 rs11090885 chr22:46951637 C/A cg04500879 chr22:46327243 WNT7B 0.27 4.53 0.38 1.35e-5 Urate levels in obese individuals; TGCT cis rs2180341 0.842 rs7739679 chr6:127545428 G/A cg24812749 chr6:127587940 RNF146 0.91 6.39 0.5 3.02e-9 Breast cancer; TGCT cis rs57590327 0.503 rs1524557 chr3:81892031 A/G cg07356753 chr3:81810745 GBE1 -0.67 -6.18 -0.49 8.32e-9 Extraversion; TGCT cis rs6733011 0.628 rs6726156 chr2:99458607 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -4.72 -0.39 6.14e-6 Bipolar disorder; TGCT cis rs6988636 1.000 rs13260798 chr8:124190192 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs1552244 0.608 rs2075310 chr3:10067651 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.32 -4.67 -0.39 7.58e-6 Alzheimer's disease; TGCT cis rs9787249 0.957 rs3738673 chr1:40204823 C/T cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs7647973 0.626 rs9835157 chr3:49797769 G/A cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.75 -0.39 5.61e-6 Menarche (age at onset); TGCT cis rs2204008 0.684 rs11514164 chr12:38036494 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.56e-12 Bladder cancer; TGCT cis rs9894429 0.646 rs6565609 chr17:79592267 G/A cg21028142 chr17:79581711 NPLOC4 0.29 5.95 0.47 2.56e-8 Eye color traits; TGCT cis rs3771570 0.901 rs4675963 chr2:242324763 G/A cg21155796 chr2:242212141 HDLBP 0.84 6.32 0.49 4.39e-9 Prostate cancer; TGCT cis rs9926296 0.682 rs467357 chr16:89717397 A/G cg26513180 chr16:89883248 FANCA -0.68 -6.33 -0.49 4.16e-9 Vitiligo; TGCT cis rs10464366 0.560 rs12701692 chr7:39135551 A/G cg15212455 chr7:39170539 POU6F2 0.23 5.3 0.43 5.16e-7 IgG glycosylation; TGCT cis rs587847 0.737 rs4924143 chr15:37624260 A/C cg00216138 chr15:37171175 LOC145845 0.3 4.52 0.38 1.43e-5 Intraocular pressure; TGCT cis rs2180341 0.782 rs4487601 chr6:127723521 A/G cg27446573 chr6:127587934 RNF146 0.8 7.08 0.54 9.53e-11 Breast cancer; TGCT cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg02353165 chr6:42928485 GNMT 0.94 9.64 0.65 9.69e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7324557 0.717 rs9553071 chr13:24381379 A/C cg16602799 chr13:25254742 ATP12A 0.57 4.45 0.37 1.93e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs644799 0.582 rs1727149 chr11:95497171 C/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.68 -6.96 -0.53 1.76e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg05552183 chr6:42928497 GNMT 0.58 5.23 0.43 6.89e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7666738 0.515 rs13118898 chr4:98792893 T/A cg05340658 chr4:99064831 C4orf37 0.51 5.65 0.45 1.03e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs316315 chr7:65591205 C/T cg07424592 chr7:64974309 NA -1.12 -7.33 -0.55 2.55e-11 Diabetic kidney disease; TGCT cis rs10206020 0.921 rs10177509 chr2:1568536 T/C cg12573674 chr2:1569213 NA -0.49 -5.41 -0.44 3.17e-7 IgG glycosylation; TGCT cis rs2797160 1.000 rs6927161 chr6:126015954 T/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs1215050 0.740 rs783929 chr4:98972495 T/A cg17366294 chr4:99064904 C4orf37 -0.55 -5.8 -0.46 5.23e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2980436 1 rs2980436 chr8:8092025 A/G cg06636001 chr8:8085503 FLJ10661 -0.85 -8.83 -0.62 8.3e-15 Schizophrenia; TGCT cis rs7565124 1.000 rs12471796 chr2:20256192 G/A cg00462460 chr2:20212509 MATN3 -0.46 -5.01 -0.41 1.85e-6 Major depressive disorder; TGCT cis rs7611238 0.583 rs7621133 chr3:195143983 T/C cg27323046 chr3:195102265 ACAP2 0.37 4.97 0.41 2.17e-6 Body mass index; TGCT cis rs4862307 0.964 rs4862305 chr4:184996810 A/G cg06737308 chr4:185021514 ENPP6 0.45 6.71 0.52 6.04e-10 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs1943345 0.642 rs642669 chr11:82892454 A/T cg07047830 chr11:82868014 PCF11 0.53 5.23 0.43 6.89e-7 Obesity-related traits; TGCT cis rs10751667 0.666 rs10902248 chr11:957742 A/G cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs35306767 0.855 rs11253499 chr10:944090 A/C cg20503657 chr10:835505 NA 0.75 10.55 0.69 5.67e-19 Eosinophil percentage of granulocytes; TGCT trans rs77457752 0.690 rs17224436 chr9:13912875 C/T cg23609682 chr1:3070786 PRDM16 -0.52 -7.07 -0.54 9.77e-11 Breast cancer; TGCT cis rs17331151 0.505 rs13086936 chr3:52659079 T/C cg24616795 chr3:53032891 SFMBT1 0.58 4.85 0.4 3.59e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6582630 0.519 rs10880576 chr12:38497693 T/C cg26384229 chr12:38710491 ALG10B 0.82 7.5 0.56 1.07e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs17122693 0.688 rs72681637 chr14:51152761 C/A cg04730355 chr14:51134070 SAV1 1.32 11.47 0.72 3.4e-21 Cognitive performance; TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg21237687 chr17:6899380 ALOX12 0.52 5.59 0.45 1.36e-7 Tonsillectomy; TGCT cis rs797680 0.786 rs1426318 chr1:93847420 A/G cg17826107 chr1:92977322 EVI5 -0.23 -5.51 -0.44 2.01e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg12419862 chr22:24373484 LOC391322 -0.8 -8.66 -0.61 2.07e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3751972 0.911 rs4796222 chr17:26216786 A/G cg02948944 chr17:26242737 NA 0.49 7.07 0.54 1.02e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs9291683 0.595 rs35501905 chr4:10053431 C/T cg00071950 chr4:10020882 SLC2A9 0.67 8.39 0.6 9.38e-14 Bone mineral density; TGCT cis rs1949733 1.000 rs868105 chr4:8501030 G/T cg11789530 chr4:8429930 ACOX3 -0.64 -5.95 -0.47 2.52e-8 Response to antineoplastic agents; TGCT cis rs10788264 0.590 rs2421012 chr10:124063452 G/C cg09507567 chr10:124027408 NA 0.39 5.46 0.44 2.5e-7 Total body bone mineral density; TGCT cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs72781680 0.716 rs78332127 chr2:24150163 C/G cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT trans rs66573146 0.808 rs55942328 chr4:6990960 T/G cg07817883 chr1:32538562 TMEM39B 1.32 6.94 0.53 1.92e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs7267979 0.789 rs62213729 chr20:25363426 C/T cg21995068 chr20:25989032 LOC100134868 0.43 5.19 0.42 8.41e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3820928 0.874 rs1917123 chr2:227889783 T/G cg11843606 chr2:227700838 RHBDD1 -0.55 -5.05 -0.41 1.52e-6 Pulmonary function; TGCT cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg22166914 chr1:53195759 ZYG11B -0.46 -8.45 -0.6 6.74e-14 Monocyte count; TGCT cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.57e-7 Developmental language disorder (linguistic errors); TGCT cis rs3008870 1.000 rs12132068 chr1:67451924 G/T cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.89 -0.73 3.08e-22 Lymphocyte percentage of white cells; TGCT cis rs3096299 0.933 rs889576 chr16:89429653 A/G cg05504729 chr16:89399490 ANKRD11 0.2 4.45 0.37 1.92e-5 Multiple myeloma (IgH translocation); TGCT cis rs9788682 0.747 rs2036533 chr15:78781687 G/A cg24631222 chr15:78858424 CHRNA5 0.61 4.51 0.38 1.5e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs6495122 0.699 rs12905199 chr15:75070196 A/G cg10253484 chr15:75165896 SCAMP2 -0.68 -5.88 -0.47 3.53e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs78456975 1.000 rs13413356 chr2:1553849 G/T cg01028140 chr2:1542097 TPO -0.35 -4.57 -0.38 1.17e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs12210905 1.000 rs9368493 chr6:27228300 T/G cg08851530 chr6:28072375 NA 0.94 4.88 0.4 3.17e-6 Hip circumference adjusted for BMI; TGCT cis rs9467711 0.606 rs9358935 chr6:26369587 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs858239 0.600 rs7790157 chr7:23126998 G/A cg05602783 chr7:23145260 KLHL7 -0.64 -5.37 -0.43 3.69e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9926296 0.632 rs2011925 chr16:89814064 T/G cg08627397 chr16:89984028 MC1R -0.32 -4.94 -0.41 2.46e-6 Vitiligo; TGCT cis rs2439831 0.850 rs60883262 chr15:44076503 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.9 0.47 3.18e-8 Lung cancer in ever smokers; TGCT cis rs9653442 0.866 rs11123811 chr2:100760172 T/C cg22139774 chr2:100720529 AFF3 -0.45 -8.17 -0.59 2.99e-13 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg06873352 chr17:61820015 STRADA 0.56 6.19 0.49 8.27e-9 Prudent dietary pattern; TGCT cis rs769267 0.965 rs1010207 chr19:19416045 T/C cg03709012 chr19:19516395 GATAD2A 0.67 5.74 0.46 6.83e-8 Tonsillectomy; TGCT cis rs950169 0.580 rs11630887 chr15:85193015 A/T cg11189052 chr15:85197271 WDR73 0.77 6.47 0.5 2.1e-9 Schizophrenia; TGCT cis rs6987853 0.686 rs10087350 chr8:42359484 G/A cg20539142 chr8:42623718 CHRNA6 0.19 4.48 0.37 1.67e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs6598955 0.617 rs11247895 chr1:26599542 G/A cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT trans rs28735056 0.904 rs72980087 chr18:77632194 G/A cg05926928 chr17:57297772 GDPD1 -0.71 -7.6 -0.56 6.2e-12 Schizophrenia; TGCT cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg03806693 chr22:41940476 POLR3H -1.01 -10.3 -0.68 2.33e-18 Vitiligo; TGCT cis rs9486715 1.000 rs9398148 chr6:97063555 A/G cg18709589 chr6:96969512 KIAA0776 -0.77 -7.12 -0.54 7.74e-11 Headache; TGCT cis rs9549367 0.789 rs2302757 chr13:113909339 A/G cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs1018836 0.886 rs10283086 chr8:91616651 G/A cg16814680 chr8:91681699 NA -0.83 -8.65 -0.61 2.22e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg19045956 chr2:200819837 C2orf60;C2orf47 0.55 5.87 0.47 3.71e-8 Osteoporosis; TGCT cis rs909674 0.515 rs9611170 chr22:39784845 G/C cg01416388 chr22:39784598 NA -0.74 -7.48 -0.56 1.16e-11 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9611565 0.592 rs12484254 chr22:41962003 T/A cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs4888262 0.514 rs8048239 chr16:74578317 A/T cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 7.94e-11 Testicular germ cell tumor; TGCT cis rs10464366 0.544 rs6952466 chr7:39155032 A/T cg15212455 chr7:39170539 POU6F2 0.31 7.11 0.54 7.92e-11 IgG glycosylation; TGCT cis rs782590 0.935 rs782606 chr2:55886602 T/C cg03859395 chr2:55845619 SMEK2 0.91 10.8 0.7 1.46e-19 Metabolic syndrome; TGCT cis rs6089829 1.000 rs62207535 chr20:61669187 A/G cg08045932 chr20:61659980 NA 0.49 9.23 0.64 9.11e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs2963155 0.518 rs853179 chr5:142634773 G/T cg17617527 chr5:142782415 NR3C1 0.85 6.29 0.49 4.9e-9 Breast cancer; TGCT cis rs12477438 0.798 rs13409996 chr2:99575497 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.65 -0.61 2.22e-14 Chronic sinus infection; TGCT cis rs7618915 0.571 rs17264436 chr3:52610651 T/A cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs7615952 0.551 rs6438945 chr3:125634473 G/A cg05084668 chr3:125655381 ALG1L -0.63 -4.62 -0.38 9.36e-6 Blood pressure (smoking interaction); TGCT cis rs2013441 1.000 rs2158473 chr17:20139090 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs4803468 1.000 rs2231940 chr19:41944237 T/C cg09537434 chr19:41945824 ATP5SL 0.91 10.05 0.67 9.48e-18 Height; TGCT cis rs7666738 0.830 rs6830124 chr4:99054872 C/T cg17366294 chr4:99064904 C4orf37 -0.74 -7.44 -0.56 1.43e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7805747 0.961 rs10265221 chr7:151414329 T/C cg17611936 chr7:151411526 PRKAG2 0.56 6.71 0.52 6.25e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs7020830 0.898 rs7846747 chr9:37167539 A/C cg14294708 chr9:37120828 ZCCHC7 1.27 18.18 0.85 8.66e-37 Schizophrenia; TGCT cis rs7043114 0.525 rs7850432 chr9:95130510 G/A cg14631576 chr9:95140430 CENPP -0.27 -4.47 -0.37 1.75e-5 Height; TGCT cis rs11711311 1.000 rs2603792 chr3:113509187 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.7 -6.64 -0.51 8.96e-10 IgG glycosylation; TGCT cis rs12134133 1.000 rs10442696 chr1:207438128 A/T cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs933688 1.000 rs11948075 chr5:90680579 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.05 0.59 5.84e-13 Smoking behavior; TGCT cis rs1057239 0.739 rs1014554 chr1:175133626 A/G cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Diastolic blood pressure; TGCT cis rs11792861 0.926 rs1051474 chr9:111881856 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.6 0.38 1.02e-5 Menarche (age at onset); TGCT cis rs7666738 0.546 rs1813970 chr4:98887167 A/G cg17366294 chr4:99064904 C4orf37 -0.67 -5.88 -0.47 3.59e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6089829 0.962 rs3746747 chr20:61667631 T/C cg03213289 chr20:61660250 NA 0.67 9.64 0.65 9.17e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7017914 0.905 rs1389206 chr8:71924862 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs9902453 0.817 rs4794861 chr17:28183174 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.79 0.52 4.12e-10 Coffee consumption (cups per day); TGCT cis rs826838 0.967 rs7963716 chr12:38876090 C/T cg13010199 chr12:38710504 ALG10B 0.67 5.72 0.46 7.57e-8 Heart rate; TGCT cis rs908922 0.887 rs1415432 chr1:152480654 G/A cg20991723 chr1:152506922 NA 0.45 5.74 0.46 7e-8 Hair morphology; TGCT cis rs1218582 0.710 rs4845685 chr1:154878300 C/A cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs5750830 0.649 rs7949 chr22:39827553 G/A cg05872129 chr22:39784769 NA -0.98 -10.82 -0.7 1.27e-19 Intelligence (multi-trait analysis); TGCT cis rs1552244 1.000 rs3846177 chr3:10068572 G/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9549260 0.709 rs9549240 chr13:41186644 T/G cg21288729 chr13:41239152 FOXO1 1.01 10.53 0.69 6.43e-19 Red blood cell count; TGCT cis rs763014 0.898 rs916416 chr16:632198 T/A cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs2204008 0.807 rs12816136 chr12:38456037 A/G cg26384229 chr12:38710491 ALG10B -0.8 -7.43 -0.56 1.51e-11 Bladder cancer; TGCT cis rs4862750 0.914 rs6553028 chr4:187876046 T/C cg11301795 chr4:187892539 NA -0.34 -5.2 -0.42 7.94e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs3845702 1.000 rs9989852 chr2:180839707 G/A cg01881094 chr2:180872142 CWC22 -0.68 -6.06 -0.48 1.51e-8 Schizophrenia; TGCT cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs2458413 0.542 rs2853146 chr8:105370179 G/A cg04554929 chr8:105342491 NA 0.48 5.77 0.46 5.95e-8 Paget's disease; TGCT cis rs380904 0.963 rs410836 chr8:144576849 A/G cg22012530 chr8:144635309 GSDMD 0.49 4.97 0.41 2.16e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs9399135 0.967 rs2327580 chr6:135364417 A/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs4319547 0.656 rs10773075 chr12:122814236 G/A cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.62 -0.38 9.46e-6 Body mass index; TGCT cis rs1552244 1.000 rs17032268 chr3:10067972 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs7264396 0.790 rs6058283 chr20:34216276 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.67 -0.39 7.62e-6 Total cholesterol levels; TGCT cis rs7394579 1 rs7394579 chr11:61581450 A/G cg19610905 chr11:61596333 FADS2 -0.96 -8.96 -0.63 4.02e-15 Red cell distribution width;Mean platelet volume; TGCT cis rs12549902 0.871 rs4736819 chr8:41509915 C/T cg00088007 chr8:41504566 NKX6-3 0.3 4.69 0.39 7.04e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs11190604 1.000 rs11190558 chr10:102209397 C/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6121246 0.529 rs6060296 chr20:30198480 T/C cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.39e-6 Mean corpuscular hemoglobin; TGCT cis rs8020441 0.588 rs67963325 chr14:51181339 C/G cg04730355 chr14:51134070 SAV1 1.01 7.33 0.55 2.58e-11 Cognitive performance; TGCT cis rs68170813 0.559 rs1018947 chr7:106851939 A/T cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.43e-8 Coronary artery disease; TGCT cis rs12902680 0.710 rs8036009 chr15:46419244 G/A cg13605988 chr15:45421612 DUOX1;DUOXA1 0.33 4.59 0.38 1.08e-5 Neuroticism; TGCT cis rs7666738 0.830 rs13138059 chr4:99050430 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs730566 1.000 rs730566 chr3:48487048 G/T cg07636037 chr3:49044803 WDR6 -0.61 -4.86 -0.4 3.47e-6 Prion diseases; TGCT trans rs7618501 0.633 rs12485600 chr3:50025530 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.9 0.66 2.18e-17 Intelligence (multi-trait analysis); TGCT cis rs3015497 0.616 rs11157759 chr14:51087263 A/G cg04730355 chr14:51134070 SAV1 -0.61 -6.01 -0.48 1.89e-8 Mean platelet volume; TGCT trans rs7824557 0.564 rs2572379 chr8:11237480 A/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs1552244 0.872 rs115331527 chr3:10154504 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs8031584 0.697 rs798080 chr15:31122169 T/C cg14829155 chr15:31115871 NA 0.37 4.9 0.4 2.96e-6 Huntington's disease progression; TGCT cis rs6882046 0.513 rs194225 chr5:88001186 A/G cg22951263 chr5:87985283 NA -0.61 -6.54 -0.51 1.47e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg03517284 chr6:25882590 NA -0.66 -7.18 -0.54 5.71e-11 Blood metabolite levels; TGCT cis rs13242816 1.000 rs62468973 chr7:116125834 G/T cg02799643 chr7:116139180 CAV2 -0.45 -5.46 -0.44 2.49e-7 P wave duration; TGCT cis rs6671200 0.607 rs1927043 chr1:95667251 G/A cg06440946 chr1:95699313 RWDD3 -0.65 -5.51 -0.44 1.95e-7 Stearic acid (18:0) levels; TGCT cis rs77140172 0.677 rs77860352 chr4:89627774 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.28 5.48 0.44 2.32e-7 Post bronchodilator FEV1; TGCT cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs12200560 0.505 rs4839848 chr6:97076577 G/A cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs4272321 1 rs4272321 chr7:157951835 A/G cg03180552 chr7:157981849 PTPRN2 0.31 4.77 0.39 5.14e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg15242686 chr22:24348715 GSTTP1 -0.46 -5.33 -0.43 4.42e-7 S-phenylmercapturic acid levels in smokers; TGCT cis rs2239815 0.515 rs12170231 chr22:29237824 C/T cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs4629710 0.592 rs749375 chr6:131553692 C/G cg12606694 chr6:131520996 AKAP7 0.4 4.72 0.39 6.18e-6 Multiple myeloma (IgH translocation); TGCT trans rs11082490 0.947 rs12604912 chr18:43420584 G/C cg05654096 chr12:106477691 NUAK1 0.55 6.66 0.51 8.03e-10 Response to paliperidone in schizophrenia (positive Marder score);Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7246657 0.943 rs2126977 chr19:37995747 C/G cg18154014 chr19:37997991 ZNF793 -0.71 -5.05 -0.41 1.51e-6 Coronary artery calcification; TGCT cis rs11190604 0.943 rs113791644 chr10:102324330 T/G cg16342193 chr10:102329863 NA -0.39 -4.65 -0.39 8.29e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6922269 0.673 rs6902496 chr6:151261637 C/T cg06091934 chr6:150278437 NA -0.3 -5.22 -0.42 7.21e-7 Coronary heart disease; TGCT cis rs7236492 0.683 rs78250476 chr18:77198934 G/A cg15644404 chr18:77186268 NFATC1 -0.35 -4.76 -0.39 5.22e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs317689 0.613 rs315112 chr12:69785926 T/A cg11871910 chr12:69753446 YEATS4 0.57 5.09 0.42 1.27e-6 Response to diuretic therapy; TGCT cis rs13191362 1.000 rs67747005 chr6:163150845 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.9 7.83 0.58 1.87e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6503863 1 rs6503863 chr17:56517034 G/A cg12560992 chr17:57184187 TRIM37 0.61 6.97 0.53 1.65e-10 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg02725872 chr8:58115012 NA -0.38 -4.66 -0.39 8.13e-6 Developmental language disorder (linguistic errors); TGCT cis rs981844 0.617 rs4077965 chr4:154710520 G/C cg14289246 chr4:154710475 SFRP2 1.08 10.27 0.68 2.72e-18 Response to statins (LDL cholesterol change); TGCT cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.819 rs62318904 chr4:99036101 A/T cg18180107 chr4:99064573 C4orf37 0.59 5.37 0.43 3.73e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2295359 0.892 rs11209004 chr1:67613932 G/A cg08029281 chr1:67600428 NA 0.4 4.6 0.38 1.02e-5 Psoriasis; TGCT cis rs7953249 0.656 rs1732391 chr12:121392341 C/T cg02403541 chr12:121454288 C12orf43 -0.62 -5.3 -0.43 5.11e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs13326165 0.760 rs2335640 chr3:52368387 T/C cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6570726 0.755 rs2103633 chr6:145894021 C/T cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs950027 0.967 rs2643718 chr15:45794662 T/C cg26924012 chr15:45694286 SPATA5L1 0.46 4.85 0.4 3.7e-6 Response to fenofibrate (adiponectin levels); TGCT cis rs11190604 1.000 rs10883499 chr10:102232188 T/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3858526 0.959 rs61876224 chr11:5952859 G/A cg05234568 chr11:5960015 NA -0.44 -4.52 -0.38 1.44e-5 DNA methylation (variation); TGCT cis rs4891159 0.548 rs12454625 chr18:74128751 A/G cg24786174 chr18:74118243 ZNF516 0.67 13.58 0.77 2.65e-26 Longevity; TGCT cis rs12110303 1 rs12110303 chr5:90662839 G/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.09 10.08 0.67 8e-18 Breast cancer; TGCT cis rs9807989 0.839 rs11695627 chr2:102970105 A/G cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs2070488 0.775 rs6794397 chr3:38559307 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.71 6.89 0.53 2.46e-10 Electrocardiographic conduction measures; TGCT cis rs769267 0.931 rs15622 chr19:19468734 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.73 -6.5 -0.5 1.8e-9 Tonsillectomy; TGCT cis rs17345786 0.817 rs11720560 chr3:101328484 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.88 9.23 0.64 9.1e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.688 rs2135219 chr1:154857217 G/A cg06221963 chr1:154839813 KCNN3 -0.73 -12.14 -0.74 8.04e-23 Prostate cancer; TGCT cis rs11688237 0.901 rs4662352 chr2:144559796 T/C cg07409629 chr2:144282743 ARHGAP15 -0.36 -4.59 -0.38 1.05e-5 Chin dimples; TGCT cis rs2046867 0.818 rs17010195 chr3:72872852 A/G cg25664220 chr3:72788482 NA 0.52 6.37 0.5 3.28e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs644799 1.000 rs527899 chr11:95529242 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs524281 0.861 rs3825067 chr11:65878419 A/G cg00563793 chr11:65837595 PACS1 -0.53 -4.56 -0.38 1.23e-5 Electroencephalogram traits; TGCT cis rs10193935 0.748 rs11124879 chr2:42697576 C/A cg27598129 chr2:42591480 NA 0.38 5.14 0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.887 rs28699126 chr2:26357294 C/T cg22920501 chr2:26401640 FAM59B -0.72 -6.26 -0.49 5.68e-9 Gut microbiome composition (summer); TGCT cis rs8078723 0.677 rs8073254 chr17:38149350 C/G cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs11098499 0.865 rs11098513 chr4:120316075 A/G cg09307838 chr4:120376055 NA 0.7 6.94 0.53 1.9e-10 Corneal astigmatism; TGCT cis rs6988636 1.000 rs57902736 chr8:124189893 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9341808 0.628 rs2490245 chr6:80892427 A/G cg08355045 chr6:80787529 NA 0.31 5.1 0.42 1.26e-6 Sitting height ratio; TGCT cis rs7605378 0.964 rs2689763 chr2:200689555 G/A cg17644776 chr2:200775616 C2orf69 0.29 5.51 0.44 1.94e-7 Osteoporosis; TGCT cis rs62380364 0.837 rs17487515 chr5:88149291 A/G cg22951263 chr5:87985283 NA -0.48 -4.62 -0.38 9.39e-6 Intelligence (multi-trait analysis); TGCT cis rs8141529 0.732 rs5752798 chr22:29181868 A/G cg02153584 chr22:29168773 CCDC117 0.73 6.22 0.49 7.04e-9 Lymphocyte counts; TGCT cis rs3015497 0.586 rs12587842 chr14:51092562 A/G cg04730355 chr14:51134070 SAV1 -0.64 -6.04 -0.48 1.64e-8 Mean platelet volume; TGCT cis rs68170813 0.523 rs4730241 chr7:107057361 G/A cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.49 4.88 0.4 3.23e-6 Blood metabolite levels; TGCT cis rs208520 0.754 rs851594 chr6:66876695 A/G cg07460842 chr6:66804631 NA -0.91 -9.43 -0.65 2.99e-16 Exhaled nitric oxide output; TGCT cis rs56104184 0.775 rs73061692 chr19:49399676 T/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4523957 0.583 rs4349181 chr17:2040963 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs968451 0.789 rs1569500 chr22:39683515 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.83 8.2 0.59 2.51e-13 Primary biliary cholangitis; TGCT cis rs10504229 0.679 rs12679941 chr8:58051812 G/T cg20607798 chr8:58055168 NA 0.44 4.6 0.38 1.01e-5 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs7772486 0.875 rs1412080 chr6:146417304 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.3 0.64 6.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs497273 0.534 rs9431 chr12:121202664 A/C cg02419362 chr12:121203948 SPPL3 0.19 4.52 0.38 1.43e-5 Systemic lupus erythematosus; TGCT cis rs2455799 0.613 rs13078485 chr3:15883236 T/C cg16303742 chr3:15540471 COLQ -0.25 -4.8 -0.4 4.53e-6 Mean platelet volume; TGCT cis rs10489202 0.683 rs7515429 chr1:168066659 A/G cg24449463 chr1:168025552 DCAF6 -0.55 -5.73 -0.46 7.31e-8 Schizophrenia; TGCT cis rs2730245 0.527 rs842707 chr7:158656012 C/T cg11984989 chr7:158649758 WDR60 1.0 7.7 0.57 3.71e-12 Height; TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs28595532 0.920 rs55668908 chr4:119769799 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs79349575 0.783 rs9912829 chr17:46982749 G/C cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs7824557 0.602 rs7833966 chr8:11206220 C/G cg21775007 chr8:11205619 TDH 0.73 7.08 0.54 9.46e-11 Retinal vascular caliber; TGCT cis rs9677476 0.516 rs2032953 chr2:232035793 C/T cg07929768 chr2:232055508 NA 0.33 5.24 0.43 6.78e-7 Food antigen IgG levels; TGCT cis rs6433857 0.505 rs1542036 chr2:181350009 A/C cg23363182 chr2:181467187 NA -0.32 -4.85 -0.4 3.59e-6 Body mass index; TGCT cis rs10744422 1.000 rs897385 chr12:123341297 A/G cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg20007245 chr22:24372913 LOC391322 -0.8 -8.6 -0.61 2.9e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9300255 0.507 rs1615350 chr12:123650335 C/T cg00376283 chr12:123451042 ABCB9 0.78 6.68 0.51 7.16e-10 Neutrophil percentage of white cells; TGCT cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg02458000 chr6:26745757 NA 0.51 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.903 rs11253488 chr10:922482 G/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs554111 0.634 rs1453265 chr1:21277711 C/T cg01072550 chr1:21505969 NA 0.35 5.36 0.43 3.88e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs4665809 0.590 rs4665315 chr2:26416036 T/G cg26119090 chr2:26468346 HADHA;HADHB -0.92 -6.8 -0.52 3.96e-10 Gut microbiome composition (summer); TGCT cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg02725872 chr8:58115012 NA 0.39 4.84 0.4 3.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs708686 0.553 rs778809 chr19:5830302 A/G cg25387410 chr19:5844109 FUT3 0.19 4.45 0.37 1.89e-5 Vitamin B12 levels; TGCT cis rs9650657 0.644 rs6601535 chr8:10695652 G/C cg16664915 chr8:10907788 XKR6 -0.29 -4.71 -0.39 6.47e-6 Neuroticism; TGCT cis rs7652177 0.905 rs2220895 chr3:171941098 T/C cg03587978 chr3:172165696 GHSR 0.27 4.46 0.37 1.84e-5 Height; TGCT trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg18110333 chr6:292329 DUSP22 -0.66 -7.25 -0.55 3.96e-11 Menopause (age at onset); TGCT cis rs6754311 0.731 rs218174 chr2:136658345 C/T cg07169764 chr2:136633963 MCM6 -0.56 -5.39 -0.44 3.39e-7 Mosquito bite size; TGCT cis rs6725041 0.819 rs4350692 chr2:213090220 T/C cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs9611565 0.649 rs126092 chr22:42178441 A/G cg03806693 chr22:41940476 POLR3H 0.92 8.66 0.61 2.13e-14 Vitiligo; TGCT cis rs3749237 1.000 rs6804655 chr3:49738945 C/T cg10152585 chr3:50297680 NA 0.49 4.47 0.37 1.77e-5 Resting heart rate; TGCT trans rs1005277 0.579 rs1780136 chr10:38501453 A/G cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs7568458 0.905 rs6547620 chr2:85755928 C/T cg17127132 chr2:85788382 GGCX 0.72 6.69 0.51 6.94e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6534347 0.573 rs6829845 chr4:123510766 C/T cg10583651 chr4:123538969 IL21 0.35 4.68 0.39 7.33e-6 Type 1 diabetes; TGCT cis rs17270561 1.000 rs12211184 chr6:25823774 G/A cg17042849 chr6:26104293 HIST1H4C -0.91 -6.17 -0.48 9.01e-9 Iron status biomarkers; TGCT cis rs868036 0.718 rs28399056 chr15:68116010 C/A cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs1964356 0.967 rs17701675 chr8:8850633 A/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.55 -0.51 1.36e-9 Mean corpuscular volume; TGCT cis rs9467711 1.000 rs9467708 chr6:26327956 T/C cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs2624839 0.704 rs13067082 chr3:50221715 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.78 -6.97 -0.53 1.68e-10 Intelligence (multi-trait analysis); TGCT cis rs593982 0.920 rs521678 chr11:65485727 T/G cg08755490 chr11:65554678 OVOL1 1.37 8.14 0.59 3.46e-13 Atopic dermatitis; TGCT cis rs6964587 1.000 rs10225885 chr7:91671007 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs9646954 0.542 rs3828193 chr2:101031561 A/C cg08017756 chr2:100939284 LONRF2 0.29 4.53 0.38 1.39e-5 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.603 rs7537618 chr1:15977682 G/A cg05660106 chr1:15850417 CASP9 0.79 7.46 0.56 1.29e-11 Systolic blood pressure; TGCT cis rs981844 0.816 rs74549610 chr4:154710464 C/G cg14289246 chr4:154710475 SFRP2 1.05 9.32 0.64 5.44e-16 Response to statins (LDL cholesterol change); TGCT cis rs7769051 1.000 rs6910639 chr6:133120553 A/G cg22852734 chr6:133119734 C6orf192 1.22 6.9 0.53 2.34e-10 Type 2 diabetes nephropathy; TGCT cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg13393036 chr8:95962371 TP53INP1 -0.59 -8.08 -0.59 4.84e-13 Type 2 diabetes; TGCT cis rs9325144 0.555 rs1843867 chr12:38703855 A/G cg26384229 chr12:38710491 ALG10B -0.68 -6.27 -0.49 5.35e-9 Morning vs. evening chronotype; TGCT cis rs1949733 1.000 rs6447875 chr4:8503206 T/C cg13073564 chr4:8508604 NA -0.47 -5.05 -0.41 1.55e-6 Response to antineoplastic agents; TGCT cis rs7726839 0.574 rs11134148 chr5:637107 C/T cg20362242 chr5:692897 TPPP 0.52 4.65 0.39 8.29e-6 Obesity-related traits; TGCT cis rs3617 0.625 rs6445541 chr3:52880128 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.49 4.67 0.39 7.57e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4072705 0.646 rs7037254 chr9:127245412 C/T cg13476313 chr9:127244764 NR5A1 -0.31 -5.18 -0.42 8.87e-7 Menarche (age at onset); TGCT cis rs7267979 0.934 rs2261115 chr20:25259807 G/A cg03522245 chr20:25566470 NINL 0.64 6.81 0.52 3.7e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7824557 0.564 rs2572395 chr8:11235360 A/C cg21775007 chr8:11205619 TDH -0.64 -6.25 -0.49 6.11e-9 Retinal vascular caliber; TGCT cis rs4478858 0.698 rs10914370 chr1:31854955 T/C cg00250761 chr1:31883323 NA -0.25 -4.45 -0.37 1.88e-5 Alcohol dependence; TGCT cis rs10114408 0.885 rs10821243 chr9:96638066 C/A cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs111803315 1.000 rs111745772 chr14:60011260 A/G cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs9291683 0.679 rs13137795 chr4:10051506 G/A cg00071950 chr4:10020882 SLC2A9 0.68 8.55 0.61 3.86e-14 Bone mineral density; TGCT cis rs896854 0.573 rs13271375 chr8:95853907 A/G cg13393036 chr8:95962371 TP53INP1 -0.51 -6.26 -0.49 5.79e-9 Type 2 diabetes; TGCT cis rs853679 0.517 rs1853097 chr6:28058635 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs3087591 1.000 rs2525578 chr17:29711411 A/G cg24425628 chr17:29625626 OMG;NF1 -0.49 -7.37 -0.55 2.07e-11 Hip circumference; TGCT cis rs61990749 0.597 rs717683 chr14:78255453 A/G cg02301378 chr14:78227641 SNW1;C14orf178 0.61 4.52 0.38 1.43e-5 Fibroblast growth factor basic levels; TGCT cis rs1799949 1.000 rs8176109 chr17:41265776 A/G cg23758822 chr17:41437982 NA 0.71 6.77 0.52 4.56e-10 Menopause (age at onset); TGCT cis rs9467711 0.591 rs9467622 chr6:25854644 C/A cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7236492 0.688 rs7241538 chr18:77191247 C/T cg15644404 chr18:77186268 NFATC1 -0.35 -4.67 -0.39 7.83e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs904251 0.797 rs1776460 chr6:37485484 A/G cg01843034 chr6:37503916 NA -0.5 -6.03 -0.48 1.71e-8 Cognitive performance; TGCT cis rs2075165 0.901 rs949464 chr1:156272271 C/T cg16558208 chr1:156270281 VHLL 0.27 4.83 0.4 3.87e-6 Tonsillectomy; TGCT cis rs4663866 1.000 rs34897410 chr2:239182123 T/C cg17283117 chr2:239148619 HES6 1.0 4.6 0.38 1.03e-5 Irritable bowel syndrome; TGCT cis rs57920188 0.584 rs12080516 chr1:4089613 C/T cg20703997 chr1:4087676 NA 0.49 6.2 0.49 7.57e-9 Interleukin-17 levels; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs909674 0.515 rs9611170 chr22:39784845 G/C cg02038168 chr22:39784481 NA -0.72 -6.04 -0.48 1.67e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs8177253 0.828 rs8177259 chr3:133480388 T/C cg01448562 chr3:133502909 NA -0.33 -6.71 -0.52 6.07e-10 Iron status biomarkers; TGCT cis rs11690935 0.921 rs4668414 chr2:172704291 A/C cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.1 -0.74 9.69e-23 Schizophrenia; TGCT cis rs66573146 1.000 rs56178503 chr4:6961748 C/T cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs910316 0.934 rs8016330 chr14:75657507 G/T cg08847533 chr14:75593920 NEK9 -0.94 -9.91 -0.66 2.11e-17 Height; TGCT cis rs968567 0.689 rs61897795 chr11:61618169 A/G cg19610905 chr11:61596333 FADS2 -0.73 -4.61 -0.38 9.71e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs7582180 0.676 rs11691135 chr2:100934038 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.95e-6 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.615 rs216462 chr17:28895897 T/C cg13385521 chr17:29058706 SUZ12P -0.9 -5.43 -0.44 2.88e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs2749592 0.550 rs7081464 chr10:37883937 C/T cg25427524 chr10:38739819 LOC399744 0.3 5.5 0.44 2.04e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs17384381 0.636 rs11161615 chr1:85906816 A/G cg16011679 chr1:85725395 C1orf52 -0.78 -6.73 -0.52 5.6e-10 Lobe attachment (rater-scored or self-reported); TGCT trans rs3780486 0.801 rs56687083 chr9:33132134 A/G cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs1891498 0.625 rs11552588 chr1:147245383 T/C cg17941330 chr1:147245494 GJA5 0.36 4.76 0.39 5.28e-6 Cognitive performance; TGCT cis rs2549003 1.000 rs6894655 chr5:131818649 T/C cg21138405 chr5:131827807 IRF1 0.2 5.08 0.41 1.36e-6 Asthma (sex interaction); TGCT cis rs6121246 0.567 rs6120815 chr20:30184866 T/C cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs9486715 0.867 rs11152924 chr6:96877383 A/G cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs2732480 0.577 rs2732457 chr12:48758379 A/G cg04545296 chr12:48745243 ZNF641 -0.35 -4.48 -0.37 1.68e-5 Hemoglobin concentration;Red blood cell count;Hematocrit; TGCT cis rs1215050 0.791 rs165244 chr4:98687889 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.53 0.45 1.77e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9400467 0.506 rs4639374 chr6:111458270 A/G cg15721981 chr6:111408429 SLC16A10 0.71 4.59 0.38 1.05e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs9527 0.614 rs4919691 chr10:104624475 A/C cg04362960 chr10:104952993 NT5C2 0.56 4.79 0.4 4.65e-6 Arsenic metabolism; TGCT cis rs62244186 0.715 rs11130032 chr3:44704083 G/A cg21672276 chr3:44754072 ZNF502 -0.43 -4.76 -0.39 5.31e-6 Depressive symptoms; TGCT cis rs933688 0.938 rs12110065 chr5:90718474 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.65e-14 Smoking behavior; TGCT cis rs3931020 0.548 rs969435 chr1:75273866 A/G cg10128416 chr1:75198403 TYW3;CRYZ -0.42 -4.63 -0.38 9.15e-6 Resistin levels; TGCT cis rs1372520 0.766 rs2583961 chr4:90779758 A/G cg15133208 chr4:90757351 SNCA -0.53 -6.26 -0.49 5.76e-9 Neuroticism; TGCT cis rs17387100 0.901 rs73230225 chr4:15983944 C/T cg13480465 chr4:16795757 LDB2 -0.42 -4.86 -0.4 3.45e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs6701037 0.566 rs10753091 chr1:175134571 T/C cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs4285028 0.699 rs73855465 chr3:121574219 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.79 -6.66 -0.51 8.01e-10 Multiple sclerosis; TGCT cis rs11719291 0.915 rs1048940 chr3:48725707 C/T cg00383909 chr3:49044727 WDR6 1.54 5.91 0.47 3.14e-8 Cognitive function; TGCT cis rs4819052 0.851 rs2838856 chr21:46680766 T/G cg06618935 chr21:46677482 NA -0.36 -5.37 -0.43 3.7e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9486719 0.947 rs2472908 chr6:96875998 A/T cg06623918 chr6:96969491 KIAA0776 1.01 8.73 0.62 1.42e-14 Migraine;Coronary artery disease; TGCT cis rs4851254 0.660 rs56037757 chr2:100690130 A/G cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs11711311 1.000 rs2305545 chr3:113499733 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs526231 0.853 rs377192 chr5:102603554 C/T cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs11264213 0.901 rs2765013 chr1:36374101 C/T cg07093915 chr1:36184400 C1orf216 0.67 4.62 0.38 9.5e-6 Schizophrenia; TGCT cis rs9911578 0.757 rs4793954 chr17:56629527 G/T cg05425664 chr17:57184151 TRIM37 0.59 4.95 0.41 2.38e-6 Intelligence (multi-trait analysis); TGCT cis rs950027 0.620 rs1346267 chr15:45690989 A/G cg26924012 chr15:45694286 SPATA5L1 0.79 8.8 0.62 1e-14 Response to fenofibrate (adiponectin levels); TGCT cis rs2645424 0.550 rs28577034 chr8:11708715 A/T cg18999641 chr8:11876646 NA 0.21 4.46 0.37 1.8e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs2445762 0.518 rs6493496 chr15:51628119 A/T cg00184732 chr15:51633821 GLDN 0.45 5.09 0.42 1.31e-6 Hormone measurements; TGCT cis rs981844 0.922 rs75543972 chr4:154664792 G/C cg14289246 chr4:154710475 SFRP2 1.0 8.25 0.6 1.96e-13 Response to statins (LDL cholesterol change); TGCT cis rs31872 0.521 rs246050 chr5:140326860 T/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Visceral adipose tissue adjusted for BMI; TGCT cis rs9921338 0.961 rs55707838 chr16:11378075 C/T cg00044050 chr16:11439710 C16orf75 -0.85 -6.04 -0.48 1.64e-8 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs3096299 0.685 rs3803681 chr16:89544756 C/T cg02244288 chr16:89573955 SPG7 -0.3 -4.5 -0.37 1.53e-5 Multiple myeloma (IgH translocation); TGCT cis rs8177253 0.901 rs9843728 chr3:133501407 C/T cg08048268 chr3:133502702 NA -0.65 -9.92 -0.67 2.02e-17 Iron status biomarkers; TGCT trans rs35851103 0.627 rs58602899 chr8:11848833 G/T cg15556689 chr8:8085844 FLJ10661 0.86 8.71 0.62 1.61e-14 Neuroticism; TGCT cis rs2204008 0.837 rs11181857 chr12:38413255 C/G cg13010199 chr12:38710504 ALG10B 0.57 4.52 0.38 1.41e-5 Bladder cancer; TGCT cis rs2404602 0.646 rs3764245 chr15:77223176 G/C cg22467129 chr15:76604101 ETFA -0.46 -4.67 -0.39 7.65e-6 Blood metabolite levels; TGCT cis rs7845219 0.544 rs10956930 chr8:95919786 C/G cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs2235649 0.625 rs56206107 chr16:1947425 A/G cg02432467 chr16:1963432 HS3ST6 -0.32 -4.86 -0.4 3.45e-6 Blood metabolite levels; TGCT cis rs3733585 0.631 rs4697924 chr4:10124239 A/G cg00071950 chr4:10020882 SLC2A9 -0.48 -4.93 -0.4 2.57e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2535633 0.631 rs2710314 chr3:52969128 T/C cg11645453 chr3:52864694 ITIH4 -0.28 -4.98 -0.41 2.12e-6 Body mass index; TGCT cis rs7267979 0.727 rs4815431 chr20:25532405 T/C cg16686733 chr20:25566563 NINL -0.52 -5.05 -0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs13108871 chr4:98803872 T/C cg17366294 chr4:99064904 C4orf37 0.65 6.69 0.51 7e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9733 0.543 rs72702558 chr1:150683251 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs2842992 0.672 rs4708845 chr6:160219601 T/G cg11366901 chr6:160182831 ACAT2 1.03 6.98 0.53 1.59e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs7937682 0.889 rs7926485 chr11:111536670 G/A cg09085632 chr11:111637200 PPP2R1B -1.14 -11.73 -0.73 7.67e-22 Primary sclerosing cholangitis; TGCT cis rs9303401 0.734 rs8073316 chr17:57211381 A/T cg12560992 chr17:57184187 TRIM37 -0.46 -4.54 -0.38 1.31e-5 Cognitive test performance; TGCT cis rs60871478 0.636 rs4721600 chr7:871728 C/T cg00475322 chr7:917719 C7orf20 0.48 4.71 0.39 6.54e-6 Cerebrospinal P-tau181p levels; TGCT cis rs12220238 1.000 rs11000887 chr10:75897542 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs951366 0.668 rs823154 chr1:205762406 C/T cg11965913 chr1:205819406 PM20D1 0.61 9.38 0.64 3.9e-16 Menarche (age at onset); TGCT cis rs1218582 0.772 rs7528532 chr1:154874440 C/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg09359103 chr1:154839909 KCNN3 0.61 11.79 0.73 5.54e-22 Prostate cancer; TGCT cis rs9914544 0.545 rs9903574 chr17:18768582 C/T cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs1443512 0.812 rs1992563 chr12:54330441 G/T cg17708016 chr12:54321992 NA 0.57 4.67 0.39 7.84e-6 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); TGCT cis rs61776719 0.875 rs4072980 chr1:38456106 G/A cg12658694 chr1:38397304 INPP5B -0.51 -5.13 -0.42 1.06e-6 Coronary artery disease; TGCT cis rs12681287 0.547 rs71502658 chr8:87478785 T/A cg27223183 chr8:87520930 FAM82B -0.89 -6.34 -0.49 3.84e-9 Caudate activity during reward; TGCT trans rs9388451 0.839 rs3966775 chr6:126067655 C/A cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.3 -0.6 1.49e-13 Brugada syndrome; TGCT cis rs17608059 0.518 rs4792436 chr17:13972307 T/A cg11395062 chr17:14139857 CDRT15 -0.43 -6.31 -0.49 4.48e-9 Temperament; TGCT cis rs1552244 1.000 rs6442146 chr3:10073544 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs3806843 0.576 rs246017 chr5:140335060 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs6545883 0.868 rs7594191 chr2:61840018 A/G cg15711740 chr2:61764176 XPO1 0.56 5.24 0.43 6.57e-7 Tuberculosis; TGCT trans rs916888 0.773 rs199439 chr17:44793503 A/G cg01341218 chr17:43662625 NA 1.04 7.82 0.57 1.97e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg07424592 chr7:64974309 NA 1.33 7.68 0.57 4.1e-12 Diabetic kidney disease; TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg11494091 chr17:61959527 GH2 -0.6 -14.54 -0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs5769707 0.592 rs6009783 chr22:50011001 C/G cg05373962 chr22:49881684 NA -0.29 -4.97 -0.41 2.16e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs926938 0.841 rs11588144 chr1:115239355 G/A cg12756093 chr1:115239321 AMPD1 -0.53 -8.21 -0.59 2.4e-13 Autism; TGCT cis rs9913156 0.793 rs72835642 chr17:4573407 T/C cg23387401 chr17:4582204 PELP1 0.31 4.59 0.38 1.09e-5 Lymphocyte counts; TGCT cis rs2574985 0.548 rs2339506 chr10:52258698 C/T cg12753529 chr10:51525504 NA 0.23 4.55 0.38 1.27e-5 Subjective well-being; TGCT cis rs9311474 0.935 rs7622851 chr3:52333671 C/G cg10802521 chr3:52805072 NEK4 -0.59 -6.4 -0.5 2.91e-9 Electroencephalogram traits; TGCT cis rs6547741 0.844 rs7586655 chr2:27915659 A/G cg27432699 chr2:27873401 GPN1 -0.24 -6.05 -0.48 1.57e-8 Oral cavity cancer; TGCT cis rs3820928 0.839 rs13413292 chr2:227893747 G/C cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs4888262 0.508 rs4888258 chr16:74634198 G/T cg01733217 chr16:74700730 RFWD3 0.74 7.42 0.55 1.6e-11 Testicular germ cell tumor; TGCT cis rs7824557 0.524 rs7835318 chr8:10953874 G/A cg21775007 chr8:11205619 TDH -0.53 -5.04 -0.41 1.59e-6 Retinal vascular caliber; TGCT cis rs924607 1.000 rs924607 chr5:610093 C/T cg04476341 chr5:669733 TPPP -0.26 -4.86 -0.4 3.55e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs9910055 1.000 rs2071167 chr17:42287519 A/G cg19774624 chr17:42201019 HDAC5 0.79 7.37 0.55 2.08e-11 Total body bone mineral density; TGCT cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg17054783 chr10:134559939 INPP5A 0.23 4.82 0.4 4.09e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6693567 0.545 rs6699093 chr1:150440451 A/G cg09579323 chr1:150459698 TARS2 -0.52 -4.62 -0.38 9.55e-6 Migraine; TGCT cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg03517284 chr6:25882590 NA -0.58 -5.16 -0.42 9.65e-7 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs6076336 chr20:25319212 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6062509 0.839 rs3859579 chr20:62301795 A/G cg27236539 chr20:62289627 RTEL1 0.56 4.63 0.38 9.12e-6 Prostate cancer; TGCT cis rs7226408 0.857 rs2166295 chr18:34488481 G/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9291683 0.668 rs2241474 chr4:10086015 T/C cg11266682 chr4:10021025 SLC2A9 0.57 6.72 0.52 5.97e-10 Bone mineral density; TGCT cis rs8180040 0.577 rs12493425 chr3:47176946 T/G cg27129171 chr3:47204927 SETD2 0.7 8.55 0.61 3.75e-14 Colorectal cancer; TGCT cis rs6882046 0.513 rs35148765 chr5:88046158 C/A cg24804195 chr5:87968844 LOC645323 -0.6 -6.06 -0.48 1.48e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs4727027 0.933 rs12704062 chr7:148827865 G/A cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs877426 0.561 rs77687017 chr13:114827394 C/T cg16820615 chr13:114884918 RASA3 0.31 4.66 0.39 8.17e-6 Facial morphology (factor 14, intercanthal width); TGCT cis rs2413583 0.591 rs114556035 chr22:39734647 C/T cg24399712 chr22:39784796 NA 0.82 4.48 0.37 1.69e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7213347 0.581 rs7209460 chr17:2048713 C/T cg22033759 chr17:1182267 TUSC5 -0.23 -4.65 -0.39 8.4e-6 Total body bone mineral density; TGCT cis rs1865760 0.516 rs9295684 chr6:26069669 T/C cg16482183 chr6:26056742 HIST1H1C 0.57 4.99 0.41 1.99e-6 Height; TGCT cis rs9427116 0.502 rs12125166 chr1:154582129 A/G cg17218026 chr1:154582156 ADAR -0.29 -7.18 -0.54 5.65e-11 Blood protein levels; TGCT cis rs6032067 0.561 rs2743317 chr20:43936931 C/T cg16667508 chr20:43936853 MATN4;RBPJL -0.47 -6.99 -0.53 1.47e-10 Blood protein levels; TGCT cis rs11105298 0.786 rs10777186 chr12:89921277 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.91 -0.4 2.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs75768999 1 rs75768999 chr10:61690195 C/T cg14316118 chr10:61668184 CCDC6 0.43 5.5 0.44 2.03e-7 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs67311347 0.955 rs60554147 chr3:40472503 T/C cg13683864 chr3:40499215 RPL14 -1.02 -10.32 -0.68 2.06e-18 Renal cell carcinoma; TGCT cis rs2594989 0.943 rs2252601 chr3:11481234 A/G cg00170343 chr3:11313890 ATG7 0.71 5.3 0.43 5.06e-7 Circulating chemerin levels; TGCT cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg05368731 chr17:41323189 NBR1 1.17 13.27 0.77 1.49e-25 Menopause (age at onset); TGCT cis rs7220711 0.967 rs4793022 chr17:41798855 C/G cg26893861 chr17:41843967 DUSP3 0.51 4.81 0.4 4.32e-6 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs4253772 0.515 rs6007891 chr22:46756833 C/T cg24881330 chr22:46731750 TRMU 0.87 4.94 0.41 2.46e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs9527 0.640 rs7089061 chr10:104723015 C/A cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs111803315 1.000 rs113172694 chr14:59998219 T/C cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs1153858 1.000 rs67831559 chr15:45649307 G/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs8037137 1.000 rs8037137 chr15:91506637 T/C cg23684204 chr15:91497937 RCCD1 0.4 4.6 0.38 1.02e-5 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs7119 0.717 rs8033067 chr15:77825495 G/T cg27398640 chr15:77910606 LINGO1 -0.26 -4.73 -0.39 6.02e-6 Type 2 diabetes; TGCT cis rs3820068 0.603 rs3766163 chr1:15986547 T/C cg05660106 chr1:15850417 CASP9 0.81 7.67 0.57 4.28e-12 Systolic blood pressure; TGCT cis rs1008375 0.932 rs6449317 chr4:17631253 T/C cg16339924 chr4:17578868 LAP3 0.7 5.67 0.45 9.46e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2075371 0.579 rs11766422 chr7:134018160 T/C cg11752832 chr7:134001865 SLC35B4 0.63 5.07 0.41 1.41e-6 Mean platelet volume; TGCT cis rs8070128 0.583 rs7406982 chr17:17942613 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.29 0.6 1.59e-13 Total body bone mineral density; TGCT cis rs12477438 0.501 rs34272114 chr2:99737443 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs10464366 0.746 rs11760807 chr7:39142377 G/A cg18850127 chr7:39170497 POU6F2 0.27 5.7 0.46 8.11e-8 IgG glycosylation; TGCT cis rs10197940 0.624 rs10497082 chr2:152355258 T/C cg19508488 chr2:152266495 RIF1 0.72 6.55 0.51 1.38e-9 Lung cancer; TGCT cis rs7582180 0.629 rs2309798 chr2:100956949 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.95 -0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT cis rs6088580 0.634 rs6141465 chr20:32967314 T/C cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs9457247 1.000 rs2769347 chr6:167371737 T/A cg23791538 chr6:167370224 RNASET2 0.51 5.12 0.42 1.12e-6 Crohn's disease; TGCT cis rs7208859 0.673 rs11657270 chr17:29214387 A/G cg18442181 chr17:29233375 C17orf42 -0.75 -4.56 -0.38 1.2e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9611565 0.571 rs2050032 chr22:42152429 C/T cg06634786 chr22:41940651 POLR3H 0.77 6.89 0.53 2.44e-10 Vitiligo; TGCT cis rs9902453 0.935 rs7220151 chr17:28334710 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs6684514 1.000 rs12117951 chr1:156305286 G/A cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg19723775 chr5:179050963 HNRNPH1 0.59 5.85 0.46 4.19e-8 Lung cancer; TGCT cis rs17068510 0.572 rs67782723 chr8:3877427 G/C cg25338036 chr8:3047536 CSMD1 -0.43 -4.51 -0.38 1.47e-5 Cerebrospinal fluid clusterin levels; TGCT cis rs4631830 0.832 rs11005089 chr10:51510813 C/A cg10326726 chr10:51549505 MSMB 0.27 5.2 0.42 7.86e-7 Prostate-specific antigen levels; TGCT cis rs61884328 0.777 rs61897777 chr11:47133604 C/G cg13308137 chr11:47528955 CUGBP1 0.38 4.47 0.37 1.76e-5 Total body bone mineral density (age over 60); TGCT cis rs1561288 0.553 rs12233169 chr2:25329272 C/T cg15423357 chr2:25149977 NA -0.5 -4.53 -0.38 1.36e-5 Body mass index; TGCT cis rs2997447 0.846 rs3008430 chr1:26390328 A/G cg19633962 chr1:26362018 EXTL1 -0.68 -4.62 -0.38 9.47e-6 QRS complex (12-leadsum); TGCT cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs12210905 0.858 rs858988 chr6:27179195 G/A cg08851530 chr6:28072375 NA -0.99 -4.79 -0.4 4.65e-6 Hip circumference adjusted for BMI; TGCT cis rs61861422 0.516 rs12412216 chr10:134393338 C/T cg10843401 chr10:134073911 STK32C 0.3 4.52 0.38 1.4e-5 Primary sclerosing cholangitis; TGCT cis rs2463822 0.583 rs72917379 chr11:62026112 T/C cg06239285 chr11:62104954 ASRGL1 -0.96 -6.16 -0.48 9.22e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs11673344 0.504 rs6510593 chr19:37634055 A/G cg08039142 chr19:36980659 ZNF566 0.51 4.69 0.39 6.97e-6 Obesity-related traits; TGCT cis rs595982 0.527 rs17206707 chr19:49361441 A/C cg17863274 chr19:49399704 TULP2 -0.48 -6.56 -0.51 1.3e-9 Red cell distribution width; TGCT cis rs12908161 1.000 rs34570071 chr15:85280212 T/A cg12863693 chr15:85201151 NMB 0.44 5.21 0.42 7.63e-7 Schizophrenia; TGCT cis rs4788570 0.547 rs6499538 chr16:71762285 A/C cg06353428 chr16:71660113 MARVELD3 1.49 13.16 0.76 2.72e-25 Intelligence (multi-trait analysis); TGCT cis rs11148252 0.574 rs3742297 chr13:53278067 T/C cg02158880 chr13:53174818 NA 0.4 4.84 0.4 3.7e-6 Lewy body disease; TGCT cis rs4819052 0.885 rs28576202 chr21:46674684 G/A cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9914544 0.564 rs12451220 chr17:18778421 C/T cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.06e-6 Educational attainment (years of education); TGCT cis rs7224685 0.569 rs12947597 chr17:3999199 A/G cg09580393 chr17:4869866 SPAG7 0.38 4.48 0.37 1.64e-5 Type 2 diabetes; TGCT cis rs2249625 0.535 rs4616959 chr6:72828200 A/C cg24401219 chr6:72892597 RIMS1 0.58 4.91 0.4 2.85e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs4727027 0.901 rs4727019 chr7:148822266 A/G cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs593531 0.571 rs10898981 chr11:74092465 A/C cg25592907 chr11:73676012 DNAJB13 0.35 5.05 0.41 1.56e-6 Neuroticism; TGCT cis rs2463822 1.000 rs7481995 chr11:62129312 G/C cg06239285 chr11:62104954 ASRGL1 0.92 6.76 0.52 4.71e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7044106 0.791 rs4836830 chr9:123483668 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.66 7.07 0.54 1.01e-10 Hip circumference adjusted for BMI; TGCT cis rs7582180 0.629 rs4850927 chr2:100969067 A/G cg14675211 chr2:100938903 LONRF2 0.51 4.97 0.41 2.13e-6 Intelligence (multi-trait analysis); TGCT cis rs477895 0.838 rs1058735 chr11:64000410 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 6.91 0.53 2.2e-10 Mean platelet volume; TGCT cis rs6840360 0.615 rs1561917 chr4:152479233 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs8056742 0.643 rs36121983 chr16:85068419 G/C cg00229868 chr16:85520891 NA 0.42 5.17 0.42 9.14e-7 Amyotrophic lateral sclerosis; TGCT cis rs9929218 0.581 rs4783676 chr16:68801077 A/C cg01251360 chr16:68772225 CDH1 -0.25 -4.5 -0.37 1.53e-5 Colorectal cancer; TGCT cis rs6121246 0.909 rs1994249 chr20:30287593 C/T cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs16854884 0.802 rs6783329 chr3:143798454 T/G cg06585982 chr3:143692056 C3orf58 0.61 4.72 0.39 6.28e-6 Economic and political preferences (feminism/equality); TGCT cis rs6921919 0.583 rs1361385 chr6:28358320 A/G cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.32 -0.43 4.76e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9393692 0.572 rs4145878 chr6:26198046 A/T cg05868516 chr6:26286170 HIST1H4H 0.54 4.86 0.4 3.49e-6 Educational attainment; TGCT cis rs3785574 0.621 rs1051684 chr17:62006497 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.52 -4.45 -0.37 1.92e-5 Height; TGCT cis rs3818285 0.504 rs1973972 chr10:111651133 A/T cg00817464 chr10:111662876 XPNPEP1 0.28 4.88 0.4 3.21e-6 Superior crus of antihelix expression; TGCT cis rs7412746 0.553 rs59337856 chr1:150746406 G/T cg09365446 chr1:150670422 GOLPH3L 0.36 5.19 0.42 8.25e-7 Melanoma; TGCT cis rs826838 1.000 rs7975243 chr12:38849220 C/T cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs910316 0.763 rs175042 chr14:75470833 A/T cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.38e-7 Height; TGCT cis rs826838 0.559 rs4882276 chr12:38611994 T/C cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Heart rate; TGCT cis rs2535633 0.631 rs2710346 chr3:52974152 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.57 5.43 0.44 2.84e-7 Body mass index; TGCT cis rs597539 0.652 rs11603827 chr11:68719221 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.81 7.41 0.55 1.74e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9952991 0.941 rs888270 chr18:12774894 G/A cg23598886 chr18:12777645 NA -0.65 -5.91 -0.47 3.15e-8 Inflammatory skin disease; TGCT cis rs6089584 0.819 rs1467593 chr20:60601432 T/G cg16423285 chr20:60520624 NA 0.61 6.55 0.51 1.39e-9 Body mass index; TGCT trans rs4332037 0.539 rs11762545 chr7:2060775 C/T cg25206134 chr2:45395956 NA 0.96 7.31 0.55 2.89e-11 Bipolar disorder; TGCT cis rs2479724 0.870 rs3747753 chr6:41753380 G/T cg08135965 chr6:41755394 TOMM6 -0.49 -4.77 -0.39 5.02e-6 Menarche (age at onset); TGCT cis rs11172134 0.508 rs1800180 chr12:57569513 G/A cg19258868 chr12:57585184 LRP1 -0.32 -6.14 -0.48 1.01e-8 Urate levels in overweight individuals; TGCT cis rs11690935 0.632 rs6433323 chr2:172873060 A/G cg13550731 chr2:172543902 DYNC1I2 -0.54 -4.45 -0.37 1.88e-5 Schizophrenia; TGCT cis rs4862750 0.881 rs6813866 chr4:187872161 T/G cg11301795 chr4:187892539 NA -0.34 -5.03 -0.41 1.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1532993 0.518 rs10014158 chr4:98612677 T/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs67311347 0.544 rs1902073 chr3:40333497 C/T cg13683864 chr3:40499215 RPL14 -0.78 -7.45 -0.56 1.42e-11 Renal cell carcinoma; TGCT cis rs10791097 0.667 rs4937584 chr11:130741761 A/G cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs36051895 0.623 rs11790680 chr9:5248768 C/T cg02405213 chr9:5042618 JAK2 -0.7 -8.27 -0.6 1.78e-13 Pediatric autoimmune diseases; TGCT cis rs4517514 0.509 rs11018875 chr11:89876356 T/C cg05041596 chr11:89867385 NAALAD2 0.52 4.56 0.38 1.22e-5 Trans fatty acid levels; TGCT cis rs7439150 0.954 rs72679196 chr4:155473549 A/C cg22130008 chr4:155548532 NA -0.43 -5.38 -0.44 3.5e-7 Fibrinogen levels; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg04234412 chr22:24373322 LOC391322 -0.94 -12.0 -0.73 1.72e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6088580 0.634 rs6059896 chr20:33111783 T/C cg08999081 chr20:33150536 PIGU 0.28 5.56 0.45 1.61e-7 Glomerular filtration rate (creatinine); TGCT cis rs3829109 0.564 rs10781506 chr9:139271461 C/T cg13741927 chr9:139327495 INPP5E -0.23 -4.94 -0.41 2.46e-6 Peak insulin response;Acute insulin response; TGCT cis rs7940866 0.834 rs1594821 chr11:130835883 C/T cg05962950 chr11:130786565 SNX19 0.78 7.35 0.55 2.37e-11 Schizophrenia; TGCT cis rs904251 0.965 rs62406516 chr6:37439364 C/T cg08126542 chr6:37504118 NA -0.4 -5.27 -0.43 5.92e-7 Cognitive performance; TGCT cis rs10423674 0.526 rs2023878 chr19:18834124 A/G cg14292368 chr19:18793705 CRTC1 0.51 4.66 0.39 7.87e-6 Menarche (age at onset); TGCT cis rs11098499 0.909 rs28884220 chr4:120307211 A/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs523522 0.962 rs11065149 chr12:120956963 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs11098499 0.754 rs17049949 chr4:120255290 A/G cg09307838 chr4:120376055 NA 0.63 6.07 0.48 1.44e-8 Corneal astigmatism; TGCT trans rs10802346 0.545 rs1770012 chr1:246426405 A/G cg22732515 chr19:44031385 ETHE1 0.84 6.8 0.52 3.89e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs4862750 0.872 rs11947595 chr4:187899827 C/T cg03452623 chr4:187889614 NA -0.34 -4.94 -0.41 2.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs422249 0.547 rs174536 chr11:61551927 A/C cg01500311 chr11:61656094 FADS3 -0.32 -5.51 -0.44 2.02e-7 Trans fatty acid levels; TGCT cis rs904251 0.861 rs1757183 chr6:37484790 C/T cg25019722 chr6:37503610 NA 0.46 6.49 0.5 1.84e-9 Cognitive performance; TGCT cis rs908922 0.676 rs10888492 chr1:152499908 G/C cg20991723 chr1:152506922 NA 0.46 6.3 0.49 4.79e-9 Hair morphology; TGCT cis rs1348850 0.914 rs10170667 chr2:178336878 A/G cg22681709 chr2:178499509 PDE11A -0.36 -4.71 -0.39 6.46e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs780096 0.506 rs2950834 chr2:27627366 G/A cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.46 -0.37 1.84e-5 Total body bone mineral density; TGCT cis rs6570726 0.764 rs9322028 chr6:145895797 G/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs78487399 0.808 rs7599781 chr2:43678726 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs8179 0.645 rs42046 chr7:92252203 C/G cg15732164 chr7:92237376 CDK6 -0.3 -5.24 -0.43 6.81e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs7659604 0.518 rs17452156 chr4:122733623 T/C cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.23e-7 Type 2 diabetes; TGCT cis rs892961 0.965 rs312856 chr17:75401598 A/G cg05865280 chr17:75406074 SEPT9 0.27 6.47 0.5 2.03e-9 Airflow obstruction; TGCT cis rs727563 0.580 rs202626 chr22:41847190 C/A cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2760061 0.626 rs596208 chr1:228117982 G/C cg02753203 chr1:228287806 NA -0.34 -6.64 -0.51 8.69e-10 Diastolic blood pressure; TGCT cis rs9467711 0.606 rs9379857 chr6:26367654 G/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs10876993 0.928 rs2640629 chr12:58065448 C/T cg15848620 chr12:58087721 OS9 -0.71 -5.95 -0.47 2.5e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs950169 1.000 rs11638394 chr15:84778928 G/A cg17173187 chr15:85201210 NMB 0.47 5.23 0.43 7.01e-7 Schizophrenia; TGCT cis rs7605378 0.567 rs717915 chr2:200714766 C/T cg23649088 chr2:200775458 C2orf69 0.47 9.61 0.65 1.14e-16 Osteoporosis; TGCT cis rs7666738 0.830 rs4401456 chr4:98959902 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10197940 0.662 rs2432945 chr2:152278414 T/C cg06191203 chr2:152266755 RIF1 -0.71 -6.28 -0.49 5.14e-9 Lung cancer; TGCT trans rs1814175 0.541 rs12287397 chr11:49819799 G/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs2013441 0.965 rs2703808 chr17:20109665 A/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs6671200 0.573 rs3820345 chr1:95713175 C/T cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs7617773 0.817 rs9818937 chr3:48325281 G/A cg11946769 chr3:48343235 NME6 0.72 6.16 0.48 9.39e-9 Coronary artery disease; TGCT cis rs8141529 0.764 rs8137969 chr22:29228484 G/C cg02153584 chr22:29168773 CCDC117 0.68 5.77 0.46 5.95e-8 Lymphocyte counts; TGCT cis rs1552244 0.882 rs13088350 chr3:10044626 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg07157834 chr1:205819609 PM20D1 -0.36 -5.56 -0.45 1.55e-7 Monocyte percentage of white cells; TGCT cis rs939574 1.000 rs2071385 chr2:220118782 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.05 6.46 0.5 2.12e-9 Platelet distribution width; TGCT cis rs3784262 0.669 rs7171261 chr15:58356855 C/G cg12031962 chr15:58353849 ALDH1A2 0.4 5.86 0.47 3.95e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs17471911 0.708 rs2862507 chr10:100807790 T/A cg03484267 chr2:207988651 KLF7 -0.52 -6.67 -0.51 7.53e-10 Neuroticism; TGCT cis rs597539 0.652 rs646586 chr11:68681653 C/T cg06112835 chr11:68658793 MRPL21 -0.39 -6.31 -0.49 4.42e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs227917 0.891 rs6461718 chr7:23664672 G/A cg12601843 chr7:23510954 IGF2BP3 0.6 4.76 0.39 5.25e-6 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs2663905 0.706 rs7162859 chr15:81360038 C/T cg25029264 chr15:81426347 C15orf26 0.61 4.56 0.38 1.21e-5 QT interval (drug interaction); TGCT cis rs12477438 0.748 rs7558239 chr2:99640581 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs4808199 1.000 rs60321073 chr19:19499598 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.7 5.06 0.41 1.5e-6 Nonalcoholic fatty liver disease; TGCT cis rs2594714 1.000 rs2594713 chr19:13954336 G/T cg18576835 chr19:13944261 NA 0.39 4.45 0.37 1.92e-5 Breast cancer; TGCT cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg22920501 chr2:26401640 FAM59B -0.83 -6.76 -0.52 4.93e-10 Gut microbiome composition (summer); TGCT cis rs11252926 0.537 rs4881255 chr10:453638 T/C cg18196295 chr10:418757 DIP2C 0.29 4.73 0.39 5.91e-6 Psychosis in Alzheimer's disease; TGCT cis rs1008375 0.900 rs1003413 chr4:17582442 C/T cg18681998 chr4:17616180 MED28 -0.85 -7.88 -0.58 1.42e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3733585 0.673 rs6849729 chr4:9958732 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg24675658 chr1:53192096 ZYG11B -0.77 -8.79 -0.62 1.05e-14 Monocyte count; TGCT cis rs9811920 0.541 rs1016914 chr3:99640121 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.59 -6.77 -0.52 4.51e-10 Axial length; TGCT cis rs3784262 0.669 rs1061278 chr15:58246029 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.03 -0.48 1.76e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4953076 0.573 rs2054005 chr2:44401843 C/T cg04920474 chr2:44395004 PPM1B 0.56 5.58 0.45 1.43e-7 Height; TGCT cis rs7666738 0.830 rs1834645 chr4:98979593 T/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs2439831 0.702 rs495175 chr15:43798684 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.0 7.94 0.58 1.04e-12 Lung cancer in ever smokers; TGCT cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.04 6.35 0.5 3.65e-9 Gut microbiome composition (summer); TGCT cis rs9399401 0.523 rs171915 chr6:142866845 C/T cg04461802 chr6:142623433 GPR126 0.54 4.85 0.4 3.7e-6 Chronic obstructive pulmonary disease; TGCT cis rs9341808 0.718 rs9448908 chr6:80898069 C/T cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs514406 0.505 rs269289 chr1:53167151 A/C cg08859206 chr1:53392774 SCP2 -0.35 -4.99 -0.41 2.01e-6 Monocyte count; TGCT cis rs36051895 0.603 rs11795305 chr9:5179920 G/C cg02405213 chr9:5042618 JAK2 -0.71 -9.57 -0.65 1.42e-16 Pediatric autoimmune diseases; TGCT cis rs11578119 0.933 rs10919403 chr1:170414584 A/G cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.66e-8 Male-pattern baldness; TGCT cis rs9910055 0.762 rs2631299 chr17:42219773 G/T cg19774624 chr17:42201019 HDAC5 -0.82 -8.35 -0.6 1.15e-13 Total body bone mineral density; TGCT cis rs7666738 0.830 rs79075162 chr4:98960674 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9860250 0.606 rs66663898 chr3:100774092 A/G cg05801080 chr3:100119813 LNP1;TOMM70A 0.54 4.54 0.38 1.29e-5 Optic disc area; TGCT cis rs7940866 0.903 rs10750457 chr11:130850277 T/C cg12179176 chr11:130786555 SNX19 0.52 5.01 0.41 1.79e-6 Schizophrenia; TGCT cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs6088580 0.634 rs3736762 chr20:33037336 C/T cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.43 0.5 2.55e-9 Cognitive function; TGCT cis rs9906944 0.707 rs9912906 chr17:47104432 A/T cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7523273 0.526 rs733177 chr1:208046384 C/T cg22525895 chr1:207977042 MIR29B2 0.34 5.55 0.45 1.63e-7 Schizophrenia; TGCT cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs9611519 0.929 rs11090039 chr22:41496800 G/A cg13695892 chr22:41940480 POLR3H -0.52 -4.74 -0.39 5.69e-6 Neuroticism; TGCT cis rs5769765 0.862 rs138897 chr22:50231067 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.38 5.72 0.46 7.68e-8 Schizophrenia; TGCT cis rs8180040 0.726 rs4682837 chr3:46999707 C/T cg27129171 chr3:47204927 SETD2 0.73 9.4 0.65 3.53e-16 Colorectal cancer; TGCT cis rs73198271 0.628 rs76079102 chr8:8591553 A/T ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs644799 0.710 rs10765771 chr11:95521044 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.8 9.01 0.63 3.14e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs763014 0.966 rs4984677 chr16:671682 A/G cg00908189 chr16:619842 PIGQ 0.87 10.67 0.69 2.91e-19 Height; TGCT cis rs2439831 1.000 rs2439850 chr15:43784854 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.51 0.44 1.95e-7 Lung cancer in ever smokers; TGCT cis rs9926296 0.585 rs8045232 chr16:89857548 A/G cg04287289 chr16:89883240 FANCA 0.93 11.96 0.73 2.13e-22 Vitiligo; TGCT cis rs7586879 0.789 rs13035239 chr2:25134000 T/A cg01884057 chr2:25150051 NA 0.27 4.57 0.38 1.17e-5 Body mass index; TGCT cis rs796364 0.951 rs971232 chr2:200792881 C/T cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.99 0.47 2.06e-8 Bipolar disorder; TGCT cis rs4148883 0.675 rs34511427 chr4:100105405 G/T cg12011299 chr4:100065546 ADH4 0.39 5.85 0.46 4.15e-8 Alcohol dependence; TGCT cis rs9611565 0.503 rs5996062 chr22:42167464 C/G cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs8042680 0.592 rs2001217 chr15:91498246 G/T cg23684204 chr15:91497937 RCCD1 -0.3 -4.61 -0.38 9.87e-6 Type 2 diabetes; TGCT cis rs854765 0.583 rs11656840 chr17:17837354 C/T cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs1008375 1.000 rs7694020 chr4:17682597 C/T cg16339924 chr4:17578868 LAP3 0.52 4.49 0.37 1.63e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.832 rs6922788 chr6:26052291 C/T cg03517284 chr6:25882590 NA -0.65 -5.73 -0.46 7.15e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.515 rs11733968 chr4:98906448 A/C cg17366294 chr4:99064904 C4orf37 -0.62 -5.76 -0.46 6.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4242434 0.927 rs7843616 chr8:22466541 T/C cg03733263 chr8:22462867 KIAA1967 1.13 20.13 0.88 6.96e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7949030 0.626 rs7930896 chr11:62325272 A/G cg22862634 chr11:62369728 EML3;MTA2 0.71 9.04 0.63 2.55e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4788439 0.901 rs72772310 chr16:24995391 A/G cg07626409 chr16:25250191 ZKSCAN2 0.32 4.45 0.37 1.87e-5 Blood metabolite levels; TGCT cis rs9972944 0.756 rs8076925 chr17:63764616 A/C cg07283582 chr17:63770753 CCDC46 -0.23 -4.88 -0.4 3.22e-6 Total body bone mineral density; TGCT cis rs2243480 0.901 rs12530490 chr7:65691647 G/A cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg17971929 chr21:40555470 PSMG1 -0.67 -6.27 -0.49 5.46e-9 Cognitive function; TGCT cis rs12142240 0.698 rs17357676 chr1:46812444 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.79 -0.4 4.68e-6 Menopause (age at onset); TGCT cis rs6840360 0.582 rs11733820 chr4:152316139 T/C cg17479576 chr4:152424074 FAM160A1 -0.63 -6.8 -0.52 4e-10 Intelligence (multi-trait analysis); TGCT cis rs6570726 1.000 rs405622 chr6:145871897 G/T cg23711669 chr6:146136114 FBXO30 0.71 6.66 0.51 7.78e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs473651 0.935 rs541128 chr2:239336449 A/G cg21699342 chr2:239360505 ASB1 0.17 4.78 0.39 4.78e-6 Multiple system atrophy; TGCT cis rs769267 0.930 rs9917108 chr19:19572785 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.73 0.46 7.3e-8 Tonsillectomy; TGCT cis rs7043114 0.525 rs10739927 chr9:95052081 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.57 -0.45 1.53e-7 Height; TGCT cis rs7552404 0.731 rs10732723 chr1:76392437 C/T cg10523679 chr1:76189770 ACADM -0.83 -7.7 -0.57 3.78e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs524023 1.000 rs505802 chr11:64357072 T/C cg07733098 chr11:64478343 NRXN2 -0.31 -4.64 -0.38 8.56e-6 Urate levels in obese individuals; TGCT cis rs17381785 0.545 rs1494947 chr4:14969983 T/G cg12377275 chr4:15005593 CPEB2 0.72 7.04 0.53 1.18e-10 Urate levels in overweight individuals; TGCT cis rs7949030 0.504 rs2516633 chr11:62371773 A/C cg11742103 chr11:62369870 EML3;MTA2 -0.55 -6.57 -0.51 1.24e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7178424 0.742 rs1981917 chr15:62171906 A/G cg00456672 chr15:62358751 C2CD4A -0.31 -4.72 -0.39 6.37e-6 Height; TGCT cis rs6952808 0.689 rs871924 chr7:2047845 A/G cg04267008 chr7:1944627 MAD1L1 -0.41 -5.4 -0.44 3.34e-7 Bipolar disorder and schizophrenia; TGCT cis rs4631830 0.720 rs2125771 chr10:51506957 C/T cg10326726 chr10:51549505 MSMB -0.23 -4.66 -0.39 8.17e-6 Prostate-specific antigen levels; TGCT cis rs12134245 0.747 rs11164912 chr1:92005191 A/T cg02896835 chr1:92012615 NA -0.28 -4.78 -0.39 4.85e-6 Breast cancer; TGCT cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg03264133 chr6:25882463 NA -0.52 -5.53 -0.44 1.81e-7 Height; TGCT cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs35146811 0.695 rs858508 chr7:99821381 C/G cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs3824867 0.920 rs7105907 chr11:47450318 A/T cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs7542091 0.635 rs985431 chr1:210043948 A/T cg23283495 chr1:209979779 IRF6 0.55 5.47 0.44 2.34e-7 Monobrow; TGCT cis rs13108904 0.901 rs12642410 chr4:1308409 A/G cg13342137 chr4:2252803 MXD4 0.17 4.48 0.37 1.66e-5 Obesity-related traits; TGCT cis rs2050392 0.789 rs303438 chr10:30733493 C/T cg18806716 chr10:30721971 MAP3K8 0.48 5.55 0.45 1.65e-7 Inflammatory bowel disease; TGCT cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs2836974 0.583 rs9636957 chr21:40705847 G/A cg17971929 chr21:40555470 PSMG1 -0.68 -5.96 -0.47 2.42e-8 Cognitive function; TGCT cis rs6542838 0.704 rs56125264 chr2:99516699 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.25 -0.43 6.5e-7 Fear of minor pain; TGCT cis rs16854884 0.770 rs1530478 chr3:143819553 C/T cg06585982 chr3:143692056 C3orf58 0.59 4.64 0.38 8.56e-6 Economic and political preferences (feminism/equality); TGCT cis rs9486719 0.947 rs9386648 chr6:97035656 T/C cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs875971 0.895 rs6460278 chr7:65662736 T/C cg11764359 chr7:65958608 NA -0.53 -4.7 -0.39 6.81e-6 Aortic root size; TGCT cis rs9894429 0.646 rs8079963 chr17:79603285 C/T cg21028142 chr17:79581711 NPLOC4 0.29 5.95 0.47 2.56e-8 Eye color traits; TGCT cis rs9788721 1.000 rs55781567 chr15:78857986 C/G cg18825076 chr15:78729989 IREB2 -0.3 -4.47 -0.37 1.74e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg12419862 chr22:24373484 LOC391322 -0.79 -8.23 -0.59 2.19e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3820928 0.874 rs55748731 chr2:227818629 C/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.9e-6 Pulmonary function; TGCT cis rs1552244 0.882 rs3846168 chr3:9996925 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 6.57 0.51 1.28e-9 Alzheimer's disease; TGCT cis rs2836950 0.840 rs12482317 chr21:40588241 A/G cg11890956 chr21:40555474 PSMG1 -0.65 -6.19 -0.49 7.89e-9 Menarche (age at onset); TGCT cis rs6952808 0.964 rs6945719 chr7:1932688 G/A cg22963979 chr7:1858916 MAD1L1 -0.37 -5.99 -0.47 2.07e-8 Bipolar disorder and schizophrenia; TGCT cis rs1008375 0.932 rs2302391 chr4:17660237 T/C cg10189774 chr4:17578691 LAP3 0.57 4.88 0.4 3.21e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9640161 0.750 rs3735173 chr7:150020526 C/T cg17279839 chr7:150038598 RARRES2 0.43 4.59 0.38 1.06e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs11190604 1.000 rs10786597 chr10:102291287 C/T cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4862750 0.872 rs6852907 chr4:187897094 A/C cg03452623 chr4:187889614 NA -0.36 -5.3 -0.43 5.01e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs35883536 0.647 rs10875313 chr1:101043057 T/C cg14855972 chr1:101004472 GPR88 -0.24 -4.49 -0.37 1.64e-5 Monocyte count; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg10263370 chr3:44754102 ZNF502 -0.45 -5.5 -0.44 2.09e-7 Depressive symptoms; TGCT cis rs1538970 0.924 rs1494812 chr1:45876999 C/T cg05343316 chr1:45956843 TESK2 0.72 5.53 0.44 1.82e-7 Platelet count; TGCT cis rs4455778 0.580 rs4336559 chr7:49125213 G/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs12368653 0.641 rs7311632 chr12:58086340 A/C cg12615879 chr12:58013172 SLC26A10 0.49 5.9 0.47 3.27e-8 Multiple sclerosis; TGCT cis rs11190604 0.943 rs11190568 chr10:102224277 C/T cg16342193 chr10:102329863 NA -0.4 -5.12 -0.42 1.14e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg07424592 chr7:64974309 NA 1.36 7.93 0.58 1.1e-12 Diabetic kidney disease; TGCT cis rs2073300 1.000 rs6137977 chr20:23464191 G/T cg09953122 chr20:23471693 CST8 -0.67 -4.62 -0.38 9.54e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs9894429 0.646 rs9902264 chr17:79613828 G/A cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs9300255 0.739 rs11057210 chr12:123733799 A/G cg00376283 chr12:123451042 ABCB9 0.71 5.51 0.44 1.98e-7 Neutrophil percentage of white cells; TGCT cis rs694739 1.000 rs1783521 chr11:64106291 T/C cg02228329 chr11:64053129 BAD;GPR137 0.78 7.74 0.57 2.95e-12 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs4443100 0.631 rs13054904 chr22:23410918 A/T cg14186256 chr22:23484241 RTDR1 -0.58 -4.68 -0.39 7.29e-6 Serum parathyroid hormone levels; TGCT cis rs981844 0.712 rs1350189 chr4:154744951 A/T cg14289246 chr4:154710475 SFRP2 -0.99 -8.93 -0.63 4.84e-15 Response to statins (LDL cholesterol change); TGCT cis rs9527 0.615 rs11191401 chr10:104573403 A/G cg04362960 chr10:104952993 NT5C2 0.6 4.82 0.4 4.19e-6 Arsenic metabolism; TGCT cis rs6570726 0.791 rs11155432 chr6:145898761 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4319547 0.760 rs61954973 chr12:123074168 T/C cg23029597 chr12:123009494 RSRC2 -0.3 -4.92 -0.4 2.65e-6 Body mass index; TGCT cis rs9906944 0.585 rs11650936 chr17:47072261 C/G cg07075026 chr17:47091521 IGF2BP1 0.42 4.71 0.39 6.51e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs9430161 0.611 rs12081181 chr1:11034165 T/G cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs7208859 0.623 rs8075341 chr17:29136565 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs67311347 0.824 rs73073561 chr3:40357298 G/T cg13683864 chr3:40499215 RPL14 -0.92 -8.87 -0.62 6.51e-15 Renal cell carcinoma; TGCT cis rs523522 0.962 rs10774549 chr12:120891172 C/T cg27279351 chr12:120934652 DYNLL1 0.74 6.4 0.5 2.95e-9 High light scatter reticulocyte count; TGCT cis rs5758659 0.714 rs5758574 chr22:42481400 G/C cg15557168 chr22:42548783 NA 0.19 4.92 0.4 2.7e-6 Cognitive function; TGCT cis rs2839186 0.632 rs2839184 chr21:47689013 G/A cg09417038 chr21:47716443 C21orf57 -0.33 -4.56 -0.38 1.19e-5 Testicular germ cell tumor; TGCT cis rs7666738 0.830 rs7684646 chr4:99071062 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.7 0.46 8.19e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs8180040 0.966 rs57346147 chr3:47410564 C/G cg27129171 chr3:47204927 SETD2 -0.64 -7.39 -0.55 1.89e-11 Colorectal cancer; TGCT trans rs1496653 0.602 rs13072325 chr3:23550989 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs9911578 0.967 rs4932693 chr17:57110327 T/C cg12560992 chr17:57184187 TRIM37 -0.79 -9.55 -0.65 1.52e-16 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs2742417 1.000 rs1969624 chr3:45734818 C/T cg04837898 chr3:45731254 SACM1L 0.55 5.68 0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1784581 0.507 rs1790020 chr6:162366266 C/T cg17173639 chr6:162384350 PARK2 -0.41 -6.99 -0.53 1.53e-10 Itch intensity from mosquito bite; TGCT cis rs877282 0.891 rs11253393 chr10:788824 G/T cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT cis rs2204008 0.621 rs7302846 chr12:38072979 A/C cg26384229 chr12:38710491 ALG10B 0.58 4.96 0.41 2.24e-6 Bladder cancer; TGCT cis rs2836950 0.565 rs2150414 chr21:40614988 A/G cg11890956 chr21:40555474 PSMG1 -0.69 -6.62 -0.51 9.84e-10 Menarche (age at onset); TGCT cis rs9611565 0.605 rs202638 chr22:41855458 A/G cg17554472 chr22:41940697 POLR3H 0.47 5.0 0.41 1.87e-6 Vitiligo; TGCT cis rs7714584 1.000 rs4958424 chr5:150225036 C/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs2836974 0.931 rs8132285 chr21:40655752 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.61 0.65 1.14e-16 Cognitive function; TGCT cis rs11785400 1.000 rs3802232 chr8:143746701 A/G cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs763014 0.932 rs2384974 chr16:651279 C/G cg07343612 chr16:622815 PIGQ -0.41 -8.15 -0.59 3.29e-13 Height; TGCT cis rs3772130 0.583 rs7618041 chr3:121566481 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.59 5.43 0.44 2.8e-7 Cognitive performance; TGCT cis rs2485376 0.813 rs1005044 chr10:104152143 C/A cg26089160 chr10:104170217 PSD 0.52 5.09 0.42 1.3e-6 QT interval; TGCT cis rs62064224 0.818 rs11080180 chr17:30682998 G/A cg18200150 chr17:30822561 MYO1D 0.58 7.72 0.57 3.35e-12 Schizophrenia; TGCT cis rs7000551 0.581 rs11787182 chr8:22256727 T/C cg12081754 chr8:22256438 SLC39A14 0.34 4.73 0.39 6.1e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6964587 1.000 rs7806184 chr7:91601978 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs35146811 0.622 rs6946204 chr7:99589125 T/C cg13334819 chr7:99746414 C7orf59 -0.65 -5.74 -0.46 6.78e-8 Coronary artery disease; TGCT cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg26119090 chr2:26468346 HADHA;HADHB -0.85 -6.05 -0.48 1.57e-8 Gut microbiome composition (summer); TGCT cis rs3820928 0.874 rs4234066 chr2:227882180 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -4.94 -0.41 2.51e-6 Pulmonary function; TGCT cis rs4676406 0.608 rs6749767 chr2:241588985 A/G cg23888423 chr2:242254170 SEPT2;HDLBP -0.46 -4.6 -0.38 1.01e-5 Ulcerative colitis; TGCT cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2806561 0.514 rs10917360 chr1:23539010 C/T cg19743168 chr1:23544995 NA 0.45 7.73 0.57 3.21e-12 Height; TGCT trans rs10506458 1.000 rs12425655 chr12:63434463 C/T cg22491629 chr6:157744540 C6orf35 -0.88 -7.81 -0.57 2.07e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs2688608 0.592 rs7080579 chr10:75504029 T/A cg23231163 chr10:75533350 FUT11 -0.28 -4.73 -0.39 5.98e-6 Inflammatory bowel disease; TGCT cis rs875971 1.000 rs6961990 chr7:65888570 C/A cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs10927875 0.541 rs1739843 chr1:16343254 T/C cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs28595532 1.000 rs114778020 chr4:119662584 C/A cg11846333 chr4:119757529 SEC24D 0.95 4.9 0.4 2.97e-6 Cannabis dependence symptom count; TGCT cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg15659132 chr6:26577336 NA 0.49 4.58 0.38 1.1e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9972944 0.651 rs7221371 chr17:63765174 C/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs2016266 0.819 rs7398228 chr12:53660285 T/C cg16917193 chr12:54089295 NA 0.67 5.1 0.42 1.25e-6 Bone mineral density (spine);Bone mineral density; TGCT trans rs561341 1.000 rs548957 chr17:30302411 G/A cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs603424 0.593 rs3829159 chr10:102088906 C/T cg22671421 chr10:102507979 PAX2 -0.54 -4.66 -0.39 7.93e-6 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg17178900 chr1:205818956 PM20D1 0.56 7.03 0.53 1.2e-10 Menarche (age at onset); TGCT cis rs9393692 0.905 rs9379843 chr6:26289435 A/G cg13736514 chr6:26305472 NA -0.41 -5.76 -0.46 6.37e-8 Educational attainment; TGCT cis rs4253772 0.591 rs6007748 chr22:46657798 A/G cg09491104 chr22:46646882 C22orf40 -0.63 -6.39 -0.5 3.05e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs7726839 0.540 rs72703079 chr5:595173 T/C cg09021430 chr5:549028 NA -0.43 -5.83 -0.46 4.57e-8 Obesity-related traits; TGCT cis rs4478858 0.684 rs3737755 chr1:31744168 G/A cg00250761 chr1:31883323 NA -0.25 -4.48 -0.37 1.64e-5 Alcohol dependence; TGCT cis rs4862307 0.964 rs76550057 chr4:184998476 C/G cg06737308 chr4:185021514 ENPP6 0.44 6.47 0.5 2.1e-9 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs950169 0.922 rs4842946 chr15:84942331 G/A cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs9911578 1.000 rs9892062 chr17:56976981 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.716 rs117129193 chr15:76656803 A/G cg22467129 chr15:76604101 ETFA -0.57 -6.69 -0.51 6.91e-10 Blood metabolite levels; TGCT cis rs4891159 0.584 rs2848958 chr18:74157068 C/T cg24786174 chr18:74118243 ZNF516 0.64 11.14 0.71 2.17e-20 Longevity; TGCT cis rs11690935 0.959 rs6724337 chr2:172735329 C/T cg13550731 chr2:172543902 DYNC1I2 -1.17 -12.1 -0.74 9.69e-23 Schizophrenia; TGCT cis rs7267979 0.873 rs6132822 chr20:25228695 C/T cg16686733 chr20:25566563 NINL 0.52 4.89 0.4 3.02e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg10047753 chr17:41438598 NA 0.91 8.44 0.6 6.86e-14 Menopause (age at onset); TGCT cis rs17767294 0.708 rs61744109 chr6:28075519 C/T cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs6665290 0.669 rs6426558 chr1:227175367 G/T cg10327440 chr1:227177885 CDC42BPA -0.91 -15.34 -0.81 1.98e-30 Myeloid white cell count; TGCT cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg23262073 chr20:60523788 NA -0.32 -5.25 -0.43 6.45e-7 Obesity-related traits; TGCT cis rs7180079 0.620 rs1008917 chr15:65059651 A/G cg03791955 chr15:65024147 NA 0.28 4.48 0.37 1.66e-5 Monocyte count; TGCT cis rs2535633 0.594 rs2581789 chr3:53096230 C/T cg11645453 chr3:52864694 ITIH4 -0.27 -5.19 -0.42 8.41e-7 Body mass index; TGCT cis rs12620999 0.941 rs10929215 chr2:238037456 G/A cg23555395 chr2:238036564 NA -0.32 -5.53 -0.44 1.8e-7 Systemic lupus erythematosus; TGCT cis rs7584330 0.868 rs67071074 chr2:238395429 T/C cg08992911 chr2:238395768 MLPH 0.62 4.51 0.38 1.49e-5 Prostate cancer; TGCT cis rs425277 0.606 rs2460001 chr1:2111030 T/C cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.48 -0.37 1.7e-5 Height; TGCT cis rs9650657 0.682 rs6989160 chr8:10705360 A/C cg27411982 chr8:10470053 RP1L1 -0.23 -4.67 -0.39 7.7e-6 Neuroticism; TGCT cis rs425277 0.585 rs3128294 chr1:2065343 G/C cg12140144 chr1:2984275 FLJ42875;PRDM16 0.37 4.95 0.41 2.33e-6 Height; TGCT cis rs57994353 0.897 rs35526483 chr9:139364940 G/A cg13741927 chr9:139327495 INPP5E -0.26 -6.13 -0.48 1.06e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT trans rs6089829 0.851 rs4809460 chr20:61661355 T/C cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs6788371 1.000 rs6788371 chr3:187319124 C/T cg01598596 chr3:187464648 BCL6 -0.43 -4.65 -0.39 8.31e-6 Pursuit maintenance gain; TGCT cis rs2180341 0.538 rs4577822 chr6:127712911 T/G cg27446573 chr6:127587934 RNF146 0.64 6.01 0.47 1.95e-8 Breast cancer; TGCT cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs3820068 0.603 rs7529759 chr1:15977877 A/G cg05660106 chr1:15850417 CASP9 0.79 7.46 0.56 1.29e-11 Systolic blood pressure; TGCT cis rs78487399 0.808 rs79845707 chr2:43788801 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.69 4.59 0.38 1.09e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs35883536 0.647 rs10875328 chr1:101169328 C/T cg06223162 chr1:101003688 GPR88 -0.39 -6.51 -0.5 1.67e-9 Monocyte count; TGCT cis rs769267 0.965 rs7254230 chr19:19434350 C/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs13256369 0.851 rs13271698 chr8:8567539 C/A cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs739401 0.611 rs494427 chr11:3048140 A/G cg05729581 chr11:3078854 CARS -0.53 -4.94 -0.41 2.51e-6 Longevity; TGCT cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg13397359 chr6:42928475 GNMT 0.67 5.93 0.47 2.84e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs16866061 0.517 rs56337305 chr2:225475560 T/C cg22455342 chr2:225449267 CUL3 0.58 4.93 0.4 2.62e-6 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs9810089 0.934 rs10935184 chr3:136153468 T/C cg12473912 chr3:136751656 NA 0.35 4.96 0.41 2.24e-6 Gestational age at birth (child effect); TGCT cis rs67311347 0.955 rs6599100 chr3:40447362 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs12595025 1 rs12595025 chr15:91520131 C/T cg23684204 chr15:91497937 RCCD1 0.4 4.59 0.38 1.07e-5 Mean platelet volume; TGCT cis rs7811142 0.830 rs41280971 chr7:99954457 G/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs8072100 0.607 rs9894594 chr17:45461383 A/G cg08085267 chr17:45401833 C17orf57 -0.51 -5.6 -0.45 1.3e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs477895 0.713 rs3802933 chr11:63988102 C/T cg04317338 chr11:64019027 PLCB3 0.81 6.87 0.53 2.7e-10 Mean platelet volume; TGCT cis rs4711350 0.954 rs943464 chr6:33731469 A/G cg00334056 chr6:33755658 LEMD2 0.31 4.79 0.39 4.72e-6 Schizophrenia; TGCT cis rs2274273 0.712 rs7144652 chr14:55537718 G/A cg01923255 chr14:55878535 KIAA0831 0.57 4.89 0.4 3.03e-6 Protein biomarker; TGCT cis rs7666738 0.830 rs2903152 chr4:99067992 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6671200 1.000 rs62625008 chr1:95702582 A/G cg26537280 chr1:95699037 RWDD3 0.7 5.55 0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs5769765 1.000 rs2295408 chr22:50261051 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.07 -0.48 1.47e-8 Schizophrenia; TGCT cis rs3008870 1.000 rs12044278 chr1:67460977 T/C cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs10504229 0.639 rs2318146 chr8:58114873 T/G cg02725872 chr8:58115012 NA -0.37 -4.99 -0.41 1.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.643 rs612874 chr2:219492924 T/C cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7659604 0.605 rs1396080 chr4:122740454 T/G cg20573242 chr4:122745356 CCNA2 0.58 5.37 0.43 3.73e-7 Type 2 diabetes; TGCT cis rs370915 0.542 rs1425953 chr4:187833652 A/C cg19519643 chr4:187840862 NA -0.23 -4.66 -0.39 7.89e-6 Gout; TGCT cis rs12188164 1.000 rs12188164 chr5:428236 C/A cg26850624 chr5:429559 AHRR -0.2 -4.69 -0.39 7.1e-6 Cystic fibrosis severity; TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg20007245 chr22:24372913 LOC391322 -0.78 -6.39 -0.5 3.11e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs17376456 1.000 rs9968749 chr5:93509559 A/G cg25358565 chr5:93447407 FAM172A 0.95 7.97 0.58 8.71e-13 Diabetic retinopathy; TGCT cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.54 4.82 0.4 4.12e-6 Height; TGCT cis rs713587 0.521 rs6545766 chr2:25077856 C/T cg01884057 chr2:25150051 NA 0.29 5.37 0.43 3.74e-7 Body mass index in non-asthmatics; TGCT cis rs6545883 0.929 rs2463100 chr2:61659199 C/G cg15711740 chr2:61764176 XPO1 -0.54 -4.96 -0.41 2.27e-6 Tuberculosis; TGCT cis rs1403694 1.000 rs2651640 chr3:186438393 G/A cg12454167 chr3:186435060 KNG1 0.42 7.37 0.55 2.15e-11 Blood protein levels; TGCT cis rs854765 0.547 rs4365348 chr17:17912548 C/T cg04398451 chr17:18023971 MYO15A -0.31 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs17221829 0.703 rs12418019 chr11:89391757 T/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs9948 0.786 rs62156231 chr2:97425603 G/A cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs76889437 0.664 rs72807953 chr2:48959451 G/A cg25061755 chr2:48808114 STON1-GTF2A1L;STON1 0.17 4.49 0.37 1.63e-5 Facial morphology (factor 19); TGCT cis rs1975974 0.574 rs17052370 chr17:21736353 A/G cg18423549 chr17:21743878 NA 0.62 6.34 0.49 3.93e-9 Psoriasis; TGCT trans rs1814175 0.654 rs7482446 chr11:49779020 A/G cg15704280 chr7:45808275 SEPT13 -0.69 -8.05 -0.59 5.61e-13 Height; TGCT cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg01411255 chr17:61851458 DDX42;CCDC47 1.1 14.26 0.79 6.49e-28 Height; TGCT cis rs514406 0.861 rs505444 chr1:53251860 C/T cg24675658 chr1:53192096 ZYG11B -0.69 -7.8 -0.57 2.19e-12 Monocyte count; TGCT cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg03452623 chr4:187889614 NA -0.33 -4.94 -0.41 2.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7586879 0.639 rs6713978 chr2:25120851 T/C cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs9814567 1.000 rs6766897 chr3:134191303 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.42 -0.65 3.18e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9443645 0.901 rs9343844 chr6:79586463 T/A cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs3764563 1.000 rs4646530 chr19:15735238 A/T cg20725493 chr19:15740067 CYP4F8 0.49 5.34 0.43 4.2e-7 Inflammatory biomarkers; TGCT cis rs12530845 0.945 rs59664351 chr7:135314717 C/A cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs896854 0.967 rs1320164 chr8:95960767 G/A cg23172400 chr8:95962367 TP53INP1 -0.38 -6.49 -0.5 1.84e-9 Type 2 diabetes; TGCT cis rs17601876 0.814 rs34712049 chr15:51560064 C/T cg19946085 chr15:51559439 CYP19A1 -0.33 -4.99 -0.41 2.03e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs17345786 0.906 rs11710016 chr3:101120030 A/C cg11279151 chr3:101281821 RG9MTD1 0.4 8.36 0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 1.000 rs2257988 chr20:25270003 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6430585 0.583 rs6728946 chr2:136635343 C/G cg07169764 chr2:136633963 MCM6 1.26 12.74 0.75 2.78e-24 Corneal structure; TGCT cis rs477895 0.629 rs7130030 chr11:63933733 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.29 0.49 5.04e-9 Mean platelet volume; TGCT cis rs9916302 0.904 rs55689507 chr17:37404436 G/C cg07936489 chr17:37558343 FBXL20 -0.65 -5.24 -0.43 6.62e-7 Glomerular filtration rate (creatinine); TGCT cis rs35264875 1.000 rs72919430 chr11:68829817 G/T cg02660097 chr11:68866761 NA 0.32 4.8 0.4 4.55e-6 Blond vs. brown hair color; TGCT cis rs9329221 0.905 rs10283145 chr8:10241411 C/T cg27411982 chr8:10470053 RP1L1 -0.21 -4.6 -0.38 1.05e-5 Neuroticism; TGCT cis rs6087990 0.842 rs4911105 chr20:31330413 G/A cg13636640 chr20:31349939 DNMT3B 1.03 14.85 0.8 2.67e-29 Ulcerative colitis; TGCT cis rs4803468 0.967 rs4803462 chr19:41908936 T/A cg09537434 chr19:41945824 ATP5SL -0.92 -10.64 -0.69 3.55e-19 Height; TGCT cis rs9467711 0.651 rs17526722 chr6:25918855 G/A cg16898833 chr6:26189333 HIST1H4D 1.23 5.03 0.41 1.65e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7647973 0.826 rs9834535 chr3:49378797 A/T cg07636037 chr3:49044803 WDR6 0.73 5.93 0.47 2.78e-8 Menarche (age at onset); TGCT cis rs9473924 0.505 rs9473931 chr6:50851411 C/G cg14470998 chr6:50812995 TFAP2B 1.37 8.44 0.6 7.05e-14 Body mass index; TGCT cis rs7474896 0.515 rs2738203 chr10:38277596 G/A cg25427524 chr10:38739819 LOC399744 0.34 4.54 0.38 1.3e-5 Obesity (extreme); TGCT cis rs6424115 0.830 rs2501426 chr1:24199364 G/A cg15997130 chr1:24165203 NA 0.86 9.44 0.65 2.86e-16 Immature fraction of reticulocytes; TGCT cis rs4699052 0.590 rs28728298 chr4:104282850 A/T cg16532752 chr4:104119610 CENPE -0.5 -4.75 -0.39 5.48e-6 Testicular germ cell tumor; TGCT cis rs9397585 0.588 rs6932473 chr6:153438573 A/T cg24028809 chr6:153414101 RGS17 0.22 4.66 0.39 8.15e-6 Body mass index; TGCT cis rs9674544 0.757 rs6504593 chr17:47132819 T/C cg20966754 chr17:47091339 IGF2BP1 -0.4 -4.47 -0.37 1.74e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs3806843 0.576 rs246059 chr5:140325010 G/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs6922617 0.786 rs73417295 chr6:41344173 C/G cg07798131 chr6:41471673 NA 0.98 4.85 0.4 3.6e-6 Alzheimer's disease biomarkers; TGCT cis rs9303401 0.614 rs34058624 chr17:57118121 T/C cg25039879 chr17:56429692 SUPT4H1 0.57 5.14 0.42 1.03e-6 Cognitive test performance; TGCT cis rs28595532 0.920 rs116559327 chr4:119754526 T/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs9972944 0.631 rs6504345 chr17:63757052 T/G cg07283582 chr17:63770753 CCDC46 -0.24 -4.84 -0.4 3.72e-6 Total body bone mineral density; TGCT cis rs10479542 0.766 rs6894980 chr5:178974592 C/T cg19723775 chr5:179050963 HNRNPH1 0.48 4.76 0.39 5.33e-6 Lung cancer; TGCT cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs67311347 0.544 rs9877105 chr3:40333366 T/C cg13683864 chr3:40499215 RPL14 -0.78 -7.45 -0.56 1.42e-11 Renal cell carcinoma; TGCT cis rs7000551 0.725 rs2248987 chr8:22399002 C/G cg12081754 chr8:22256438 SLC39A14 0.31 5.03 0.41 1.7e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg03060546 chr3:49711283 APEH 0.59 5.58 0.45 1.41e-7 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs910187 0.571 rs3746489 chr20:45801716 C/T cg27589058 chr20:45804311 EYA2 -0.39 -8.26 -0.6 1.86e-13 Migraine; TGCT cis rs769267 0.930 rs4808957 chr19:19567248 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.2 0.49 7.59e-9 Tonsillectomy; TGCT cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.07 0.41 1.43e-6 Menopause (age at onset); TGCT cis rs4409675 0.576 rs7356 chr1:28218100 T/C cg23691781 chr1:28212827 C1orf38 0.26 5.32 0.43 4.68e-7 Corneal astigmatism; TGCT cis rs6490294 0.799 rs61670030 chr12:112351854 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.69e-8 Mean platelet volume; TGCT cis rs3617 0.539 rs4687687 chr3:52948332 A/G cg10802521 chr3:52805072 NEK4 0.57 6.57 0.51 1.22e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1008375 0.966 rs4698621 chr4:17587565 C/T cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs524281 0.861 rs7931544 chr11:65917034 C/T cg00563793 chr11:65837595 PACS1 0.58 4.92 0.4 2.66e-6 Electroencephalogram traits; TGCT cis rs67311347 0.544 rs9833640 chr3:40354941 T/A cg13683864 chr3:40499215 RPL14 -0.84 -7.85 -0.58 1.71e-12 Renal cell carcinoma; TGCT cis rs968451 0.724 rs5757599 chr22:39670181 A/C cg17798944 chr22:39715225 SNORD43;RPL3 0.67 6.41 0.5 2.74e-9 Primary biliary cholangitis; TGCT cis rs2191566 0.664 rs55958002 chr19:44543788 A/T cg03039196 chr19:44506973 ZNF230 0.53 4.47 0.37 1.78e-5 Acute lymphoblastic leukemia (childhood); TGCT trans rs459571 0.959 rs455381 chr9:136905577 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.72 -7.83 -0.58 1.87e-12 Platelet distribution width; TGCT cis rs13191362 1.000 rs7764785 chr6:163009967 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4665809 0.878 rs892448 chr2:26366205 A/G cg25036284 chr2:26402008 FAM59B -0.56 -4.78 -0.39 4.9e-6 Gut microbiome composition (summer); TGCT cis rs7772486 0.727 rs2235481 chr6:146056848 T/C cg13319975 chr6:146136371 FBXO30 0.74 6.68 0.51 7.36e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs67478160 0.643 rs11628332 chr14:104241141 C/T cg26031613 chr14:104095156 KLC1 -0.64 -6.7 -0.52 6.67e-10 Schizophrenia; TGCT cis rs4665809 0.567 rs12999875 chr2:26414847 A/C cg04944784 chr2:26401820 FAM59B 0.76 6.21 0.49 7.25e-9 Gut microbiome composition (summer); TGCT cis rs10986311 0.654 rs2416927 chr9:127078521 G/C cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -5.01 -0.41 1.82e-6 Vitiligo; TGCT cis rs644799 0.544 rs56298021 chr11:95545113 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.55 5.83 0.46 4.56e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs16867321 0.671 rs12053494 chr2:181493357 T/A cg23363182 chr2:181467187 NA -0.47 -4.98 -0.41 2.11e-6 Obesity; TGCT cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg06238570 chr21:40685208 BRWD1 -0.67 -6.61 -0.51 1.03e-9 Cognitive function; TGCT cis rs72781680 0.821 rs113014365 chr2:24159903 C/T cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs453301 0.653 rs7016139 chr8:8895470 A/G cg00184457 chr8:8946301 NA -0.24 -4.54 -0.38 1.34e-5 Joint mobility (Beighton score); TGCT cis rs763014 0.932 rs2384974 chr16:651279 C/G cg00908189 chr16:619842 PIGQ 0.85 10.4 0.68 1.33e-18 Height; TGCT cis rs4372836 1.000 rs55835850 chr2:28949296 T/C cg09522027 chr2:28974177 PPP1CB 0.59 4.98 0.41 2.05e-6 Body mass index; TGCT cis rs9906944 0.545 rs11079851 chr17:47092310 G/C cg07075026 chr17:47091521 IGF2BP1 -0.44 -4.6 -0.38 1.02e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT trans rs1005277 0.540 rs1814077 chr10:37992018 G/C cg17830980 chr10:43048298 ZNF37B -0.63 -6.95 -0.53 1.86e-10 Extrinsic epigenetic age acceleration; TGCT cis rs5750830 0.649 rs4821894 chr22:39809820 G/C cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs7727544 0.716 rs11949055 chr5:131576737 T/C cg22598563 chr5:131563921 P4HA2 -0.29 -4.66 -0.39 7.88e-6 Blood metabolite levels; TGCT cis rs892961 0.867 rs312909 chr17:75413954 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.73 0.52 5.56e-10 Airflow obstruction; TGCT cis rs2153904 0.793 rs1772145 chr1:205695695 C/T cg23034840 chr1:205782522 SLC41A1 0.72 5.44 0.44 2.74e-7 Prostate-specific antigen levels; TGCT cis rs9583531 0.527 rs12875067 chr13:111365104 A/G cg24331049 chr13:111365604 ING1 0.76 7.31 0.55 2.95e-11 Coronary artery disease; TGCT cis rs7226408 0.846 rs2121024 chr18:34488206 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1023500 0.596 rs133352 chr22:42434022 C/A cg15557168 chr22:42548783 NA -0.21 -5.34 -0.43 4.22e-7 Schizophrenia; TGCT cis rs7216064 0.953 rs62086043 chr17:65968003 A/G cg12091567 chr17:66097778 LOC651250 -0.78 -5.91 -0.47 3.11e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs611744 0.967 rs686265 chr8:109199763 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs7312933 0.703 rs1059360 chr12:42554505 A/G cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg25036284 chr2:26402008 FAM59B 0.65 5.13 0.42 1.07e-6 Gut microbiome composition (summer); TGCT cis rs12681288 0.550 rs76893867 chr8:962618 G/C cg04851639 chr8:1020857 NA -0.3 -5.08 -0.41 1.36e-6 Schizophrenia; TGCT cis rs9902453 1.000 rs62070270 chr17:28263980 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 6.62 0.51 9.51e-10 Coffee consumption (cups per day); TGCT cis rs9914988 0.619 rs35477460 chr17:27320276 C/T cg17523868 chr17:27313033 SEZ6 -0.56 -4.77 -0.39 5.17e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs6089584 0.606 rs7270666 chr20:60577598 C/T cg13770153 chr20:60521292 NA -0.42 -5.13 -0.42 1.08e-6 Body mass index; TGCT cis rs1635 0.655 rs75885713 chr6:28312356 G/A cg24848467 chr6:28134517 ZNF389 -0.58 -4.7 -0.39 6.75e-6 Schizophrenia; TGCT cis rs6088590 0.965 rs6087639 chr20:33443866 G/A cg24642439 chr20:33292090 TP53INP2 0.71 6.32 0.49 4.28e-9 Coronary artery disease; TGCT cis rs1534166 0.647 rs9853615 chr3:133519981 C/T cg20276088 chr3:133502917 NA -0.22 -4.48 -0.37 1.7e-5 Alcohol consumption (transferrin glycosylation); TGCT cis rs1670533 1.000 rs6599278 chr4:1058798 C/T cg27284194 chr4:1044797 NA 0.66 5.81 0.46 4.98e-8 Recombination rate (females); TGCT cis rs736408 0.561 rs2276815 chr3:52853747 C/G cg10802521 chr3:52805072 NEK4 -0.64 -6.51 -0.5 1.69e-9 Bipolar disorder; TGCT cis rs7772486 0.790 rs9497425 chr6:146234197 G/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10489202 0.632 rs202259 chr1:167962072 G/A cg24449463 chr1:168025552 DCAF6 -0.59 -7.11 -0.54 8.22e-11 Schizophrenia; TGCT cis rs367943 1.000 rs348962 chr5:112819086 C/T cg12552261 chr5:112820674 MCC 0.25 5.01 0.41 1.84e-6 Type 2 diabetes; TGCT cis rs988712 0.607 rs11030084 chr11:27643725 C/T cg10635145 chr11:27742435 BDNF -0.37 -4.6 -0.38 1.03e-5 Obesity; TGCT cis rs35934224 0.831 rs1044732 chr22:19863142 T/C cg11182965 chr22:19864308 TXNRD2 -0.39 -5.24 -0.43 6.67e-7 Glaucoma (primary open-angle); TGCT cis rs8017423 0.838 rs11845950 chr14:90723962 T/A cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs2296887 0.591 rs11191284 chr10:104164210 G/C cg26089160 chr10:104170217 PSD -0.68 -6.13 -0.48 1.1e-8 Parkinson's disease; TGCT cis rs853679 0.517 rs12174753 chr6:28042465 C/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs72615157 0.606 rs941288 chr7:99776808 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.94 0.41 2.51e-6 Lung function (FEV1/FVC); TGCT cis rs6121246 0.580 rs6121016 chr20:30245239 C/T cg21427119 chr20:30132790 HM13 -0.33 -4.49 -0.37 1.59e-5 Mean corpuscular hemoglobin; TGCT cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.14 0.42 1.06e-6 Platelet count; TGCT cis rs10984561 0.737 rs12237970 chr9:122251005 C/G cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs4783244 0.828 rs9940266 chr16:82653548 C/T cg09415485 chr16:82663111 CDH13 -0.24 -4.51 -0.38 1.47e-5 Adiponectin levels; TGCT cis rs6666258 1.000 rs34106427 chr1:154813988 G/A cg06418219 chr1:154948305 SHC1;CKS1B 0.63 5.1 0.42 1.21e-6 Atrial fibrillation; TGCT cis rs13202913 0.709 rs11965449 chr6:151830598 C/T cg14416726 chr6:151773293 C6orf211;RMND1 0.64 4.62 0.38 9.44e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs3617 0.573 rs62253583 chr3:52928334 G/A cg11645453 chr3:52864694 ITIH4 -0.27 -5.14 -0.42 1.05e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs916888 0.821 rs199512 chr17:44857352 T/C cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10088262 0.629 rs7833650 chr8:124822969 C/T cg02993010 chr8:124780839 FAM91A1 -0.61 -4.63 -0.38 9.02e-6 Pancreatic cancer; TGCT cis rs35771425 0.509 rs3120782 chr1:211419700 A/T cg25617285 chr1:211431773 RCOR3 -0.49 -5.68 -0.45 9.25e-8 Educational attainment (years of education); TGCT cis rs6088580 0.634 rs6087588 chr20:33066369 T/C cg08999081 chr20:33150536 PIGU 0.28 5.6 0.45 1.3e-7 Glomerular filtration rate (creatinine); TGCT cis rs10782582 0.609 rs5745325 chr1:76269460 G/A cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs7584330 0.628 rs7591065 chr2:238390739 G/T cg08992911 chr2:238395768 MLPH 0.72 4.64 0.38 8.67e-6 Prostate cancer; TGCT cis rs66887589 0.616 rs7659403 chr4:120207254 T/A cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.14e-5 Diastolic blood pressure; TGCT trans rs7613875 0.600 rs1061474 chr3:50144951 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.82 -8.52 -0.61 4.53e-14 Body mass index; TGCT cis rs3806843 0.568 rs2530232 chr5:140082878 A/G cg19875535 chr5:140030758 IK -0.36 -5.93 -0.47 2.79e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7567389 0.568 rs7568070 chr2:127953054 A/C cg09760422 chr2:128146352 NA 0.38 4.9 0.4 2.98e-6 Self-rated health; TGCT cis rs763121 0.853 rs5750659 chr22:39068789 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs1878931 0.513 rs35160989 chr16:3405506 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.93 10.4 0.68 1.34e-18 Body mass index (adult); TGCT cis rs617219 0.710 rs10474578 chr5:78542290 T/C cg23987322 chr5:78407566 BHMT 0.35 4.69 0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs765787 0.530 rs2413784 chr15:45530516 A/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs8016982 0.855 rs10149681 chr14:81686319 G/A cg01989461 chr14:81687754 GTF2A1 0.61 5.15 0.42 9.99e-7 Schizophrenia; TGCT cis rs854765 0.583 rs4414547 chr17:17859052 G/T cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg15659132 chr6:26577336 NA 0.87 10.72 0.69 2.19e-19 Intelligence (multi-trait analysis); TGCT cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg22168489 chr12:122356033 WDR66 0.2 4.73 0.39 6.08e-6 Mean corpuscular volume; TGCT cis rs2070488 1.000 rs2268753 chr3:38500189 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.89 9.58 0.65 1.34e-16 Electrocardiographic conduction measures; TGCT cis rs10504229 0.683 rs17194995 chr8:58109220 A/C cg11062466 chr8:58055876 NA -0.43 -4.64 -0.38 8.84e-6 Developmental language disorder (linguistic errors); TGCT cis rs10197940 0.624 rs10497082 chr2:152355258 T/C cg06191203 chr2:152266755 RIF1 -0.76 -7.11 -0.54 8.05e-11 Lung cancer; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg04389838 chr3:44770851 ZNF501 -0.36 -4.66 -0.39 8.16e-6 Depressive symptoms; TGCT cis rs7044106 0.762 rs7357638 chr9:123389204 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.63 6.78 0.52 4.27e-10 Hip circumference adjusted for BMI; TGCT cis rs1865760 0.686 rs12210098 chr6:25963966 C/T cg17042849 chr6:26104293 HIST1H4C -0.62 -5.16 -0.42 9.63e-7 Height; TGCT cis rs9910055 0.659 rs227578 chr17:42210189 C/A cg19774624 chr17:42201019 HDAC5 0.89 11.12 0.71 2.32e-20 Total body bone mineral density; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs7085104 0.591 rs4919683 chr10:104585125 G/T cg04362960 chr10:104952993 NT5C2 0.54 4.66 0.39 8.08e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs10972341 0.967 rs13285401 chr9:35152858 T/C cg00812861 chr9:35114699 KIAA1539 0.34 5.24 0.43 6.81e-7 Weight; TGCT cis rs42648 0.869 rs12704518 chr7:89914388 G/T cg25739043 chr7:89950458 NA -0.73 -7.31 -0.55 2.87e-11 Homocysteine levels; TGCT cis rs2721195 0.549 rs2958492 chr8:145919126 C/T cg15857475 chr8:145742913 RECQL4;LRRC14 0.65 6.32 0.49 4.32e-9 Age at first birth; TGCT trans rs1814175 0.817 rs10839351 chr11:49758153 C/T cg15704280 chr7:45808275 SEPT13 -0.69 -7.93 -0.58 1.08e-12 Height; TGCT cis rs853679 0.517 rs9380060 chr6:28132603 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs67478160 0.643 rs12878868 chr14:104233725 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.42 -0.5 2.66e-9 Schizophrenia; TGCT cis rs6964587 0.934 rs12531561 chr7:91707780 A/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs4242434 0.927 rs2291231 chr8:22463912 C/T cg03733263 chr8:22462867 KIAA1967 1.14 20.09 0.87 8.18e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs76419734 0.850 rs112292976 chr4:106779785 C/T cg24545054 chr4:106630052 GSTCD;INTS12 1.09 4.45 0.37 1.9e-5 Post bronchodilator FEV1; TGCT cis rs1005224 0.853 rs2360035 chr14:76297093 A/T cg04684003 chr14:76127793 TTLL5;C14orf1 0.54 4.77 0.39 5.11e-6 Large artery stroke; TGCT cis rs7017914 0.935 rs56289931 chr8:71837754 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.71e-6 Bone mineral density; TGCT cis rs2016266 0.859 rs11170507 chr12:53740682 C/A cg16917193 chr12:54089295 NA -0.7 -4.68 -0.39 7.49e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs1046896 0.576 rs8082558 chr17:80695501 G/A cg00960700 chr17:80709150 TBCD 0.51 5.1 0.42 1.24e-6 Glycated hemoglobin levels; TGCT trans rs1814175 0.645 rs4625470 chr11:49983769 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs4478858 0.684 rs17440445 chr1:31722562 C/T cg00250761 chr1:31883323 NA 0.27 4.76 0.39 5.29e-6 Alcohol dependence; TGCT cis rs4455778 0.728 rs7796636 chr7:49015314 C/G cg26309511 chr7:48887640 NA -0.45 -5.26 -0.43 6.21e-7 Lung cancer in never smokers; TGCT cis rs28386778 0.863 rs2597633 chr17:61872871 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs7192750 0.538 rs4788582 chr16:71981806 A/G cg06353428 chr16:71660113 MARVELD3 0.75 6.74 0.52 5.43e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs9911578 0.935 rs7216698 chr17:57007495 G/A cg12560992 chr17:57184187 TRIM37 0.73 8.7 0.62 1.69e-14 Intelligence (multi-trait analysis); TGCT cis rs651907 0.535 rs34263427 chr3:101507805 A/G cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs926938 0.527 rs1391484 chr1:115522366 A/G cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs9952991 0.883 rs2847260 chr18:12775591 C/T cg24737193 chr18:12778029 NA 0.53 5.93 0.47 2.8e-8 Inflammatory skin disease; TGCT cis rs7666738 0.606 rs10006414 chr4:99101401 T/C cg05340658 chr4:99064831 C4orf37 0.42 4.49 0.37 1.62e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs7937682 0.855 rs539693 chr11:111477387 A/G cg09085632 chr11:111637200 PPP2R1B -1.06 -11.27 -0.71 1.04e-20 Primary sclerosing cholangitis; TGCT cis rs6088590 0.735 rs6060003 chr20:33294945 T/C cg06115741 chr20:33292138 TP53INP2 0.55 4.68 0.39 7.3e-6 Coronary artery disease; TGCT cis rs4319547 0.915 rs1473553 chr12:122985057 G/T cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.32 -0.43 4.71e-7 Body mass index; TGCT cis rs7364180 0.582 rs139568 chr22:42210985 C/T cg06634786 chr22:41940651 POLR3H 0.48 4.69 0.39 7.23e-6 Alzheimer's disease biomarkers; TGCT cis rs2050392 0.861 rs303448 chr10:30727084 G/T cg18806716 chr10:30721971 MAP3K8 -0.51 -6.0 -0.47 2.05e-8 Inflammatory bowel disease; TGCT cis rs10892173 0.765 rs1892903 chr11:117669619 A/G cg07621104 chr11:117668040 DSCAML1 0.51 5.61 0.45 1.28e-7 Myopia; TGCT cis rs4499344 0.664 rs4286210 chr19:33101221 T/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.81 0.62 9.52e-15 Mean platelet volume; TGCT cis rs992157 0.730 rs4280446 chr2:219184721 T/C cg00012203 chr2:219082015 ARPC2 0.69 6.41 0.5 2.77e-9 Colorectal cancer; TGCT cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs9381040 0.610 rs9367094 chr6:41017860 T/C cg03526776 chr6:41159608 TREML2 0.26 5.14 0.42 1.05e-6 Alzheimer's disease (late onset); TGCT cis rs10927875 0.518 rs732286 chr1:16344360 A/G cg22431228 chr1:16359049 CLCNKA -0.29 -5.94 -0.47 2.68e-8 Dilated cardiomyopathy; TGCT cis rs644799 0.526 rs693172 chr11:95636618 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.48 4.91 0.4 2.8e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9911578 0.835 rs9889419 chr17:56473259 C/T cg12560992 chr17:57184187 TRIM37 0.77 9.06 0.63 2.4e-15 Intelligence (multi-trait analysis); TGCT cis rs425277 0.538 rs169037 chr1:2095582 G/T cg24578937 chr1:2090814 PRKCZ 0.26 6.95 0.53 1.8e-10 Height; TGCT cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs975752 0.717 rs12253275 chr10:102043477 T/A cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs4849845 0.584 rs3896630 chr2:121037018 A/G cg24070213 chr2:121070622 NA 0.35 4.64 0.38 8.58e-6 Mean platelet volume; TGCT cis rs12477438 0.798 rs12477754 chr2:99628073 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs9300255 0.543 rs1617156 chr12:123590165 T/C cg00376283 chr12:123451042 ABCB9 0.7 5.17 0.42 9.08e-7 Neutrophil percentage of white cells; TGCT cis rs7949030 0.653 rs2516634 chr11:62367186 G/A cg13298116 chr11:62369859 EML3;MTA2 -0.64 -9.62 -0.65 1.04e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs17162190 0.698 rs6673072 chr1:26844074 G/C cg02450742 chr1:26856648 RPS6KA1 0.54 4.49 0.37 1.62e-5 Mean corpuscular volume; TGCT cis rs3091242 0.933 rs9438905 chr1:25764177 A/G cg09222892 chr1:25734099 RHCE -0.43 -7.07 -0.54 1.02e-10 Erythrocyte sedimentation rate; TGCT cis rs9611565 1.000 rs5751086 chr22:41768862 C/T cg17554472 chr22:41940697 POLR3H -0.44 -5.07 -0.41 1.4e-6 Vitiligo; TGCT cis rs854765 0.583 rs6502622 chr17:17834691 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs13188771 0.578 rs17137390 chr5:100918526 C/T cg17598923 chr5:101119084 NA 0.49 4.68 0.39 7.46e-6 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs72945132 0.882 rs7129843 chr11:70180381 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9611565 0.512 rs5751153 chr22:42156561 T/C cg03806693 chr22:41940476 POLR3H 1.04 10.57 0.69 5.2e-19 Vitiligo; TGCT cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6430585 0.583 rs11886852 chr2:136589379 G/A cg07169764 chr2:136633963 MCM6 1.05 9.56 0.65 1.46e-16 Corneal structure; TGCT cis rs7666738 0.830 rs7696568 chr4:99005333 A/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs67096506 chr8:58195655 G/A cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs12134133 0.752 rs61821051 chr1:207408969 C/G cg02152968 chr1:207494213 CD55 0.69 4.75 0.39 5.46e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs11840576 0.588 rs331976 chr13:110317769 G/T cg15975806 chr13:110319607 NA -0.6 -4.44 -0.37 1.95e-5 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs896854 0.654 rs10429443 chr8:95971164 A/G cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.57e-9 Type 2 diabetes; TGCT cis rs10992471 0.756 rs7848055 chr9:95115492 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.24 -0.49 6.3e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10791097 0.739 rs11222358 chr11:130730497 G/A cg05962950 chr11:130786565 SNX19 0.8 9.66 0.66 8.34e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9894429 0.966 rs6565605 chr17:79589359 C/T cg21028142 chr17:79581711 NPLOC4 0.29 6.83 0.52 3.44e-10 Eye color traits; TGCT cis rs6570726 0.935 rs385134 chr6:145851005 C/T cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs67072384 1.000 rs56693670 chr11:72445143 G/T cg03713592 chr11:72463424 ARAP1 -0.9 -4.63 -0.38 9.26e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs10479542 0.702 rs13183521 chr5:178975606 A/G cg19626725 chr5:178986131 RUFY1 -0.46 -5.87 -0.47 3.67e-8 Lung cancer; TGCT cis rs4986172 0.881 rs9894577 chr17:43223292 G/A cg10701640 chr17:43249399 NA 0.39 4.75 0.39 5.52e-6 Height; TGCT cis rs1008375 0.863 rs4590022 chr4:17614434 T/C cg18681998 chr4:17616180 MED28 1.07 11.25 0.71 1.13e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2072499 1.000 rs2241107 chr1:156182710 C/T cg24450063 chr1:156163899 SLC25A44 -1.14 -16.55 -0.83 3.47e-33 Testicular germ cell tumor; TGCT cis rs17376456 1.000 rs34013242 chr5:93507947 C/T cg21475434 chr5:93447410 FAM172A 0.62 4.5 0.37 1.54e-5 Diabetic retinopathy; TGCT cis rs72717009 0.825 rs6671753 chr1:161478708 G/A cg23840854 chr1:161414152 NA -1.0 -6.43 -0.5 2.47e-9 Rheumatoid arthritis; TGCT cis rs11190604 1.000 rs11190589 chr10:102275471 A/G cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.72e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7208859 0.623 rs1061342 chr17:29114463 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6495122 0.662 rs12898997 chr15:75090349 C/T cg10253484 chr15:75165896 SCAMP2 -0.67 -5.88 -0.47 3.51e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs35146811 0.961 rs35991721 chr7:99728790 G/T cg22906224 chr7:99728672 NA 0.55 5.05 0.41 1.52e-6 Coronary artery disease; TGCT cis rs9611565 0.729 rs12165508 chr22:41819960 T/C cg06481639 chr22:41940642 POLR3H 0.59 5.12 0.42 1.12e-6 Vitiligo; TGCT cis rs478304 0.651 rs4930312 chr11:65499719 G/A cg10518572 chr11:65560635 OVOL1 -0.24 -4.68 -0.39 7.53e-6 Acne (severe); TGCT cis rs34638657 0.702 rs11866709 chr16:82201017 A/G cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs16866061 1.000 rs72972378 chr2:225372562 A/G cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs796364 0.806 rs78527234 chr2:200913453 C/T cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs12701220 0.817 rs59471534 chr7:1085224 G/A cg27454412 chr7:1067447 C7orf50 -0.48 -4.45 -0.37 1.87e-5 Bronchopulmonary dysplasia; TGCT cis rs7584330 0.737 rs7595979 chr2:238364492 G/T cg14458575 chr2:238380390 NA 0.51 8.11 0.59 4.19e-13 Prostate cancer; TGCT cis rs9899728 0.665 rs2307008 chr17:73042682 G/A cg27626185 chr17:73056755 KCTD2 -0.66 -6.23 -0.49 6.77e-9 Alzheimer's disease or small vessel stroke; TGCT cis rs7772486 0.686 rs1337839 chr6:146010239 A/G cg23711669 chr6:146136114 FBXO30 -0.85 -9.45 -0.65 2.66e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.531 rs10199898 chr2:26445485 T/G cg04944784 chr2:26401820 FAM59B -0.76 -6.24 -0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs13256369 1.000 rs13282915 chr8:8570891 T/G cg18904891 chr8:8559673 CLDN23 0.59 5.54 0.45 1.73e-7 Obesity-related traits; TGCT cis rs6867032 0.917 rs10474733 chr5:2004160 A/G cg26168224 chr5:2018326 NA -0.38 -5.97 -0.47 2.31e-8 Gut microbiome composition (winter); TGCT cis rs4906332 1.000 rs11625172 chr14:103944912 G/A cg26031613 chr14:104095156 KLC1 -0.52 -4.72 -0.39 6.31e-6 Coronary artery disease; TGCT cis rs10504229 0.775 rs10504228 chr8:58162053 T/G cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs9972944 0.691 rs10083837 chr17:63775311 C/G cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs9677476 0.516 rs6437001 chr2:232013304 G/T cg07929768 chr2:232055508 NA 0.32 4.97 0.41 2.2e-6 Food antigen IgG levels; TGCT cis rs34526934 0.608 rs7606110 chr2:177028551 T/C cg26754761 chr2:177040938 NA -0.28 -5.22 -0.42 7.15e-7 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs17345786 1.000 rs17345786 chr3:101318318 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.86 -9.19 -0.64 1.17e-15 Colonoscopy-negative controls vs population controls; TGCT trans rs17685 0.712 rs1637049 chr7:75729975 C/G cg19862616 chr7:65841803 NCRNA00174 0.48 7.75 0.57 2.84e-12 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2243480 1.000 rs451396 chr7:65484074 T/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7914558 1.000 rs7896547 chr10:104866958 A/G cg15744005 chr10:104629667 AS3MT -0.42 -5.21 -0.42 7.57e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2228479 0.867 rs62056110 chr16:89946388 A/C cg19635926 chr16:89946313 TCF25 0.28 4.8 0.4 4.47e-6 Skin colour saturation; TGCT cis rs4319547 0.695 rs10773103 chr12:122856532 A/G cg05707623 chr12:122985044 ZCCHC8 0.62 4.87 0.4 3.32e-6 Body mass index; TGCT cis rs700590 0.632 rs244754 chr5:88144026 A/G cg22951263 chr5:87985283 NA 0.54 5.06 0.41 1.48e-6 Educational attainment (years of education); TGCT cis rs6906287 0.647 rs12665409 chr6:118685043 G/A cg21191810 chr6:118973309 C6orf204 0.26 4.46 0.37 1.85e-5 Electrocardiographic conduction measures; TGCT cis rs1697139 0.583 rs6895853 chr5:66541427 T/C cg11553311 chr5:66541588 NA 0.27 5.82 0.46 4.78e-8 Breast cancer; TGCT cis rs6671200 0.607 rs6671408 chr1:95697091 T/C cg06440946 chr1:95699313 RWDD3 -0.62 -5.26 -0.43 6.12e-7 Stearic acid (18:0) levels; TGCT cis rs17473412 0.577 rs9327301 chr5:122860170 G/A cg15125798 chr5:122621645 NA -0.53 -4.9 -0.4 2.93e-6 Total body bone mineral density; TGCT cis rs875971 0.862 rs778697 chr7:65870426 G/A cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs1971256 0.500 rs3912290 chr6:151818297 T/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.75 -4.62 -0.38 9.37e-6 Endometriosis; TGCT cis rs614226 1.000 rs1167727 chr12:120965508 C/A cg10072921 chr12:121022843 NA -0.44 -4.74 -0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs67460515 0.892 rs35310734 chr3:160943209 T/G cg03342759 chr3:160939853 NMD3 -0.49 -5.2 -0.42 7.93e-7 Parkinson's disease; TGCT cis rs4900538 0.855 rs1209151 chr14:102893756 C/T cg18135206 chr14:102964638 TECPR2 -0.2 -4.51 -0.38 1.48e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg12386194 chr3:101231763 SENP7 0.61 5.75 0.46 6.7e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs941408 1.000 rs2741990 chr19:2796644 C/T cg19676328 chr12:49525230 TUBA1B -0.77 -7.83 -0.58 1.84e-12 Total cholesterol levels; TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg25767906 chr1:53392781 SCP2 -0.51 -5.97 -0.47 2.32e-8 Monocyte count; TGCT cis rs12477438 0.605 rs4585080 chr2:99557327 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -5.34 -0.43 4.19e-7 Chronic sinus infection; TGCT cis rs514406 0.505 rs269290 chr1:53167027 A/T cg24675658 chr1:53192096 ZYG11B -0.74 -8.3 -0.6 1.52e-13 Monocyte count; TGCT cis rs9902453 0.845 rs116840018 chr17:28232049 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.26 0.55 3.67e-11 Coffee consumption (cups per day); TGCT cis rs3824867 0.920 rs80241400 chr11:47453828 T/C cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs1865760 1.000 rs6910138 chr6:25904352 C/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs6933660 0.800 rs963193 chr6:151789355 G/T cg14262678 chr6:151773367 RMND1;C6orf211 -0.51 -4.69 -0.39 7.11e-6 Menarche (age at onset); TGCT cis rs7208859 0.573 rs73267865 chr17:29064204 C/G cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2235642 0.685 rs2667681 chr16:1653206 C/T cg11375102 chr16:1583810 IFT140;TMEM204 -0.27 -4.58 -0.38 1.12e-5 Coronary artery disease; TGCT cis rs1887596 0.672 rs1831466 chr13:27231212 C/G cg01312412 chr13:27282625 NA 0.29 5.15 0.42 1.01e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs9467773 0.967 rs9358954 chr6:26531178 A/G cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs17030835 chr2:43686245 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.77 0.39 5.16e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4332037 0.539 rs56180486 chr7:2050747 C/T cg25834613 chr7:1915315 MAD1L1 -0.52 -5.08 -0.42 1.33e-6 Bipolar disorder; TGCT cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs6969780 0.673 rs2301721 chr7:27196113 C/T cg11410718 chr7:27170412 HOXA4 -0.46 -4.57 -0.38 1.18e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs3733585 0.673 rs4459990 chr4:9954005 T/C cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4788570 0.527 rs72791971 chr16:71477297 C/G cg06353428 chr16:71660113 MARVELD3 -1.37 -7.39 -0.55 1.91e-11 Intelligence (multi-trait analysis); TGCT cis rs13064411 0.696 rs7613546 chr3:113228019 G/A cg18753928 chr3:113234510 CCDC52 -0.71 -5.78 -0.46 5.63e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs644799 0.525 rs3016206 chr11:95536724 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.8 8.28 0.6 1.66e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs751728 0.626 rs57150921 chr6:33737518 T/C cg13859433 chr6:33739653 LEMD2 -0.32 -5.6 -0.45 1.29e-7 Crohn's disease; TGCT cis rs6951245 1.000 rs884977 chr7:1066410 T/C cg23708337 chr7:1209742 NA 0.51 4.5 0.37 1.56e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1005224 0.889 rs10132250 chr14:76124380 C/A cg04684003 chr14:76127793 TTLL5;C14orf1 -0.66 -6.11 -0.48 1.18e-8 Large artery stroke; TGCT cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg02487422 chr3:49467188 NICN1 0.53 4.94 0.41 2.43e-6 Menarche (age at onset); TGCT cis rs1801251 0.752 rs2675966 chr2:233735543 T/C cg08000102 chr2:233561755 GIGYF2 -0.44 -4.45 -0.37 1.87e-5 Coronary artery disease; TGCT cis rs9399135 0.967 rs2183709 chr6:135377091 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs7659604 0.539 rs56159666 chr4:122782879 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.31 -0.43 4.79e-7 Type 2 diabetes; TGCT cis rs896854 0.654 rs896847 chr8:95972551 G/A cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.51e-14 Type 2 diabetes; TGCT cis rs72717009 0.825 rs867624 chr1:161467837 A/T cg23840854 chr1:161414152 NA -1.02 -6.37 -0.5 3.42e-9 Rheumatoid arthritis; TGCT cis rs68170813 0.652 rs56949084 chr7:107157387 G/A cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs10504229 0.683 rs11786527 chr8:58131344 G/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.541 rs588770 chr2:219494638 T/C cg02176678 chr2:219576539 TTLL4 0.47 6.7 0.52 6.62e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6920965 0.563 rs1544292 chr6:126175093 G/C cg05901451 chr6:126070800 HEY2 -0.58 -5.11 -0.42 1.16e-6 High light scatter reticulocyte count; TGCT cis rs1552244 0.554 rs3846169 chr3:9997054 A/G cg00149659 chr3:10157352 C3orf10 -0.64 -4.74 -0.39 5.69e-6 Alzheimer's disease; TGCT cis rs17376456 0.877 rs35747258 chr5:93310129 C/T cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs11105298 0.838 rs10858862 chr12:89842053 T/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7937682 0.883 rs568038 chr11:111432161 A/C cg09085632 chr11:111637200 PPP2R1B 0.99 10.25 0.68 3.19e-18 Primary sclerosing cholangitis; TGCT cis rs797680 0.856 rs569414 chr1:93784901 G/A cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg03264133 chr6:25882463 NA -0.73 -7.73 -0.57 3.2e-12 Blood metabolite levels; TGCT cis rs9435341 0.896 rs1623927 chr1:107596120 T/C cg09367891 chr1:107599246 PRMT6 -0.64 -5.5 -0.44 2.07e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs9527 0.571 rs3740400 chr10:104629465 T/G cg15744005 chr10:104629667 AS3MT -0.5 -6.4 -0.5 2.92e-9 Arsenic metabolism; TGCT cis rs13394619 0.605 rs12476152 chr2:11747960 T/C cg07314298 chr2:11723111 GREB1 0.28 4.58 0.38 1.12e-5 Endometriosis; TGCT cis rs1971762 0.545 rs11170632 chr12:54047935 C/T cg16917193 chr12:54089295 NA -1.08 -11.6 -0.72 1.59e-21 Height; TGCT cis rs2290402 0.536 rs3775129 chr4:875155 G/A cg23332689 chr4:987652 IDUA;SLC26A1 0.32 4.92 0.4 2.64e-6 Type 2 diabetes; TGCT cis rs9814567 1.000 rs6763093 chr3:134254995 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs7731657 0.537 rs4705917 chr5:130206326 A/G cg08523029 chr5:130500466 HINT1 -0.59 -4.99 -0.41 1.99e-6 Fasting plasma glucose; TGCT cis rs17376456 0.757 rs10066431 chr5:93198204 A/G cg21475434 chr5:93447410 FAM172A 0.69 4.81 0.4 4.36e-6 Diabetic retinopathy; TGCT cis rs1040555 0.516 rs242547 chr20:31418581 T/C cg13636640 chr20:31349939 DNMT3B 0.79 8.47 0.61 5.92e-14 Lymphocyte percentage of white cells; TGCT cis rs6500602 0.563 rs917304 chr16:4440426 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.38 5.56 0.45 1.55e-7 Schizophrenia; TGCT cis rs9341808 0.754 rs9361591 chr6:80953255 C/A cg08355045 chr6:80787529 NA 0.29 5.1 0.42 1.23e-6 Sitting height ratio; TGCT cis rs765787 0.530 rs55920042 chr15:45541577 G/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs7659604 0.517 rs56311153 chr4:122729685 T/C cg06713675 chr4:122721982 EXOSC9 -0.69 -9.69 -0.66 7.11e-17 Type 2 diabetes; TGCT cis rs3784262 0.528 rs17820966 chr15:58336662 A/G cg12031962 chr15:58353849 ALDH1A2 0.42 6.3 0.49 4.84e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7568458 0.660 rs6547623 chr2:85801964 T/A cg17127132 chr2:85788382 GGCX 0.52 4.9 0.4 2.96e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs17102423 0.559 rs4899160 chr14:65481212 C/T cg11161011 chr14:65562177 MAX -0.46 -5.19 -0.42 8.38e-7 Obesity-related traits; TGCT cis rs2456568 0.775 rs1607404 chr11:93660449 C/G cg17595323 chr11:93583763 C11orf90 -0.47 -6.04 -0.48 1.65e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3784262 1.000 rs4369598 chr15:58318603 G/T cg12031962 chr15:58353849 ALDH1A2 -0.52 -7.98 -0.58 8.57e-13 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9560113 0.960 rs953260 chr13:112173685 C/T cg14154082 chr13:112174009 NA 0.34 4.58 0.38 1.1e-5 Menarche (age at onset); TGCT cis rs4478858 0.684 rs1532861 chr1:31766491 T/C cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs7909074 0.691 rs11239274 chr10:45393219 A/C cg04218760 chr10:45406644 TMEM72 0.25 4.83 0.4 3.87e-6 Mean corpuscular volume; TGCT cis rs9296092 0.538 rs62407564 chr6:33534010 C/T cg13560919 chr6:33536144 NA -0.23 -4.95 -0.41 2.4e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs611744 0.631 rs681963 chr8:109255032 C/A cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs6688613 0.840 rs6669886 chr1:166956710 T/C cg07049167 chr1:166818506 POGK 0.26 5.18 0.42 8.56e-7 Refractive astigmatism; TGCT cis rs10089 1.000 rs73337363 chr5:127483597 A/G cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.27e-5 Ileal carcinoids; TGCT cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs7647973 1.000 rs1464569 chr3:49460350 A/G cg07636037 chr3:49044803 WDR6 0.64 5.26 0.43 6.12e-7 Menarche (age at onset); TGCT cis rs68170813 0.641 rs74524528 chr7:107090979 G/A cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs910187 0.605 rs8124995 chr20:45811788 G/T cg27589058 chr20:45804311 EYA2 -0.38 -8.34 -0.6 1.18e-13 Migraine; TGCT cis rs7917772 0.503 rs11191347 chr10:104351617 C/T cg05855489 chr10:104503620 C10orf26 -0.61 -5.41 -0.44 3.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1997103 1.000 rs2177803 chr7:55410773 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1334894 1.000 rs72913417 chr6:35546866 C/T cg24281267 chr6:35479648 TULP1 -0.44 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs7659604 0.540 rs28615388 chr4:122678418 C/T cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.92e-6 Type 2 diabetes; TGCT cis rs208520 1.000 rs12190316 chr6:66973365 T/C cg07460842 chr6:66804631 NA 0.77 6.82 0.52 3.49e-10 Exhaled nitric oxide output; TGCT cis rs6570726 0.577 rs441982 chr6:145842848 A/G cg23711669 chr6:146136114 FBXO30 0.71 6.29 0.49 4.94e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 0.536 rs4793227 chr17:41412250 A/C cg10047753 chr17:41438598 NA 0.79 7.5 0.56 1.06e-11 Menopause (age at onset); TGCT cis rs950169 0.959 rs12911210 chr15:84792083 A/C cg11189052 chr15:85197271 WDR73 0.7 5.9 0.47 3.28e-8 Schizophrenia; TGCT cis rs12477438 0.520 rs11123761 chr2:99705903 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs2404602 0.608 rs17361504 chr15:76601871 A/G cg22467129 chr15:76604101 ETFA -0.63 -8.02 -0.58 6.71e-13 Blood metabolite levels; TGCT cis rs2463822 1.000 rs2463825 chr11:62094493 G/A cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs524023 0.957 rs893006 chr11:64365796 C/A cg07733098 chr11:64478343 NRXN2 0.32 4.76 0.39 5.35e-6 Urate levels in obese individuals; TGCT cis rs4746818 0.818 rs7076011 chr10:70900430 T/C cg11621586 chr10:70884670 VPS26A 1.21 10.66 0.69 3.17e-19 Left atrial antero-posterior diameter; TGCT cis rs10465746 0.967 rs11163874 chr1:84424437 G/C cg10977910 chr1:84465055 TTLL7 0.65 6.56 0.51 1.31e-9 Obesity-related traits; TGCT cis rs1799949 0.965 rs8176322 chr17:41195773 A/G cg05368731 chr17:41323189 NBR1 1.1 11.24 0.71 1.23e-20 Menopause (age at onset); TGCT trans rs208515 0.525 rs12193034 chr6:66677866 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs6762477 0.505 rs17304079 chr3:50085153 A/G cg14019146 chr3:50243930 SLC38A3 -0.21 -4.51 -0.38 1.47e-5 Menarche (age at onset); TGCT cis rs6089829 0.851 rs10854168 chr20:61669550 A/G cg02380750 chr20:61661411 NA 0.35 5.68 0.45 9.19e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7513165 1.000 rs11240695 chr1:204158132 C/A cg04791601 chr1:204159016 NA 0.26 4.95 0.41 2.38e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs597539 0.518 rs35093305 chr11:68730729 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.79 7.1 0.54 8.45e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6463523 0.933 rs4724821 chr7:762544 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.75 11.22 0.71 1.36e-20 Subjective well-being; TGCT cis rs7091068 0.574 rs10748610 chr10:95462235 C/G cg20715218 chr10:95462985 C10orf4 0.54 5.07 0.41 1.39e-6 Urinary tract infection frequency; TGCT cis rs600231 0.623 rs587080 chr11:65253800 A/C cg17120908 chr11:65337727 SSSCA1 -0.56 -5.19 -0.42 8.17e-7 Bone mineral density; TGCT cis rs9911578 1.000 rs3744109 chr17:56594197 C/T cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs2191566 0.960 rs11083733 chr19:44520919 G/C cg03039196 chr19:44506973 ZNF230 0.52 4.45 0.37 1.87e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs7617773 0.817 rs11130163 chr3:48312658 T/C cg11946769 chr3:48343235 NME6 0.73 6.8 0.52 3.86e-10 Coronary artery disease; TGCT cis rs12142240 0.698 rs1475388 chr1:46816465 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7584330 0.868 rs13386290 chr2:238393136 G/C cg08992911 chr2:238395768 MLPH 0.62 4.51 0.38 1.49e-5 Prostate cancer; TGCT cis rs10992471 0.605 rs7872375 chr9:95064843 C/G cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.95e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 7.8 0.57 2.16e-12 Platelet count; TGCT cis rs7267979 0.789 rs6050472 chr20:25219852 A/G cg16686733 chr20:25566563 NINL 0.49 4.53 0.38 1.36e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg11644478 chr21:40555479 PSMG1 -0.62 -5.81 -0.46 4.87e-8 Cognitive function; TGCT cis rs2072499 1.000 rs2241107 chr1:156182710 C/T cg06970220 chr1:156163860 SLC25A44 -0.68 -6.01 -0.48 1.88e-8 Testicular germ cell tumor; TGCT cis rs9611565 0.729 rs137831 chr22:41903813 A/C cg03806693 chr22:41940476 POLR3H -1.03 -11.06 -0.7 3.38e-20 Vitiligo; TGCT cis rs9611565 0.729 rs169362 chr22:41827589 G/C cg13695892 chr22:41940480 POLR3H 0.86 8.55 0.61 3.95e-14 Vitiligo; TGCT cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg10117171 chr1:25599238 RHD -0.35 -5.73 -0.46 7.34e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs9910055 0.529 rs408282 chr17:42182267 A/G cg13607699 chr17:42295918 UBTF -0.65 -5.39 -0.44 3.34e-7 Total body bone mineral density; TGCT cis rs651907 0.514 rs12636046 chr3:101434448 T/G cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.02 -0.53 1.27e-10 Colorectal cancer; TGCT cis rs7582180 0.606 rs4851299 chr2:100954191 C/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs904251 0.864 rs2797801 chr6:37487161 A/G cg25019722 chr6:37503610 NA -0.51 -7.03 -0.53 1.24e-10 Cognitive performance; TGCT cis rs72781680 0.848 rs715646 chr2:24010566 G/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT trans rs34034104 1.000 rs34034104 chr15:40725033 C/A cg01027929 chr7:26241406 HNRNPA2B1;CBX3 -0.72 -6.68 -0.51 7.22e-10 Itch intensity from mosquito bite adjusted by bite size;Itch intensity from mosquito bite; TGCT cis rs7772486 0.754 rs6915718 chr6:146100676 A/G cg23711669 chr6:146136114 FBXO30 -0.93 -10.53 -0.69 6.46e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs13108904 0.870 rs4974578 chr4:1266072 A/G cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs6671200 0.607 rs10874908 chr1:95704151 C/G cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs1862618 0.671 rs2591957 chr5:56243146 A/T cg24531977 chr5:56204891 C5orf35 0.68 7.14 0.54 6.98e-11 Initial pursuit acceleration; TGCT cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg11845111 chr2:191398756 TMEM194B 0.37 5.65 0.45 1.03e-7 Pulse pressure; TGCT trans rs459571 0.959 rs465724 chr9:136910097 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.73 -7.79 -0.57 2.29e-12 Platelet distribution width; TGCT cis rs763121 0.853 rs5757213 chr22:39053888 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs362272 0.524 rs6819202 chr4:3368264 G/A cg06533319 chr4:3265114 C4orf44 -0.25 -5.14 -0.42 1.04e-6 Serum sulfate level; TGCT cis rs9470794 0.607 rs1931761 chr6:38202822 C/G cg03166753 chr6:38683221 NA 0.6 4.53 0.38 1.37e-5 Type 2 diabetes; TGCT trans rs877282 0.891 rs11595385 chr10:800539 A/G cg22713356 chr15:30763199 NA 1.18 9.92 0.67 1.96e-17 Uric acid levels; TGCT cis rs7119038 0.818 rs10892287 chr11:118642999 C/T cg19308663 chr11:118741387 NA -0.27 -5.43 -0.44 2.86e-7 Sjögren's syndrome; TGCT cis rs1218582 0.710 rs9794000 chr1:154878876 T/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.97 -0.53 1.64e-10 Prostate cancer; TGCT cis rs10744422 1.000 rs7959441 chr12:123363825 C/T cg25930673 chr12:123319894 HIP1R -0.86 -5.08 -0.42 1.34e-6 Schizophrenia; TGCT cis rs3087591 0.960 rs757384 chr17:29596135 C/T cg24425628 chr17:29625626 OMG;NF1 0.46 7.28 0.55 3.41e-11 Hip circumference; TGCT cis rs1865760 0.964 rs6932113 chr6:25913098 C/T cg16482183 chr6:26056742 HIST1H1C 0.55 4.97 0.41 2.19e-6 Height; TGCT cis rs9818758 0.607 rs35060561 chr3:49255503 T/C cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs727505 1.000 rs66513837 chr7:124492763 A/G cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs270601 0.955 rs273911 chr5:131661526 C/G cg24060327 chr5:131705240 SLC22A5 -0.74 -7.84 -0.58 1.73e-12 Acylcarnitine levels; TGCT cis rs8017423 0.967 rs61592400 chr14:90703252 T/C cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs617219 0.698 rs72764983 chr5:78513806 T/C cg05890484 chr5:78407552 BHMT 0.39 5.31 0.43 5e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9389248 0.690 rs2294321 chr6:135253048 T/G cg22676075 chr6:135203613 NA -0.51 -5.11 -0.42 1.17e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs6684514 1.000 rs12024813 chr1:156224529 C/A cg20302342 chr1:156215951 PAQR6 0.37 4.73 0.39 6e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10876993 0.928 rs10082911 chr12:58104104 C/A cg15848620 chr12:58087721 OS9 -0.72 -6.01 -0.48 1.89e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs9359856 0.510 rs4053618 chr6:90459454 G/A cg13799429 chr6:90582589 CASP8AP2 0.45 4.66 0.39 7.9e-6 Bipolar disorder; TGCT cis rs2303745 0.589 rs11086065 chr19:17395003 A/G cg04248312 chr19:17393744 ANKLE1 -0.34 -5.7 -0.46 8.29e-8 Systemic lupus erythematosus; TGCT cis rs6547741 0.935 rs6547738 chr2:27852637 A/G cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs2735413 0.564 rs78769909 chr16:78104002 G/A cg09132178 chr16:78079569 NA 0.35 4.72 0.39 6.29e-6 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs7312933 0.576 rs11181364 chr12:42567800 C/T cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10791097 0.694 rs4937581 chr11:130740335 T/C cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6088580 0.634 rs7271970 chr20:32987666 A/G cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg24846343 chr22:24311635 DDTL 0.22 5.68 0.45 9.16e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10779751 0.770 rs1057079 chr1:11205058 A/G cg08854313 chr1:11322531 MTOR -0.81 -7.96 -0.58 9.32e-13 Body mass index; TGCT cis rs72949976 0.646 rs13029384 chr2:214029164 G/A cg08319019 chr2:214017104 IKZF2 0.87 8.64 0.61 2.34e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg27588902 chr6:42928151 GNMT -0.51 -6.07 -0.48 1.42e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs28386778 0.742 rs3020617 chr17:61947303 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.94 0.41 2.44e-6 Prudent dietary pattern; TGCT cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg16145915 chr7:1198662 ZFAND2A -0.56 -7.16 -0.54 6.17e-11 Longevity;Endometriosis; TGCT cis rs10504229 1.000 rs67913746 chr8:58177825 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2032447 0.867 rs9295683 chr6:26069495 C/T cg07061783 chr6:25882402 NA -0.57 -5.31 -0.43 4.95e-7 Intelligence (multi-trait analysis); TGCT cis rs4654899 1.000 rs6663452 chr1:21423154 T/C cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2594989 0.943 rs4580536 chr3:11422319 A/G cg00170343 chr3:11313890 ATG7 0.67 4.9 0.4 2.9e-6 Circulating chemerin levels; TGCT cis rs7085104 0.552 rs11191414 chr10:104601565 A/T cg15744005 chr10:104629667 AS3MT -0.43 -5.37 -0.43 3.77e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg00684032 chr4:1343700 KIAA1530 0.24 5.16 0.42 9.67e-7 Obesity-related traits; TGCT cis rs34783982 0.529 rs1850324 chr15:89472267 A/G cg26213453 chr15:89455860 MFGE8 0.33 5.25 0.43 6.45e-7 Squamous cell lung carcinoma; TGCT trans rs1814175 0.935 rs6485999 chr11:49658986 G/C cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs1670533 1.000 rs604597 chr4:1094151 G/A cg20518497 chr4:1046821 NA 0.27 4.46 0.37 1.82e-5 Recombination rate (females); TGCT cis rs7666738 0.830 rs28619044 chr4:98789814 G/C cg17366294 chr4:99064904 C4orf37 0.65 6.79 0.52 4.13e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg11494091 chr17:61959527 GH2 0.61 14.45 0.79 2.29e-28 Prudent dietary pattern; TGCT cis rs889312 0.500 rs11960484 chr5:56109154 C/T cg12311346 chr5:56204834 C5orf35 0.43 4.66 0.39 8.14e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs8077577 0.895 rs62073602 chr17:18057907 A/G cg09161412 chr17:18057145 MYO15A -0.64 -5.3 -0.43 5.21e-7 Obesity-related traits; TGCT cis rs6952808 0.825 rs11761818 chr7:1935273 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.53 -0.44 1.84e-7 Bipolar disorder and schizophrenia; TGCT cis rs950169 0.922 rs11631096 chr15:85100929 G/C cg17173187 chr15:85201210 NMB 0.5 5.04 0.41 1.62e-6 Schizophrenia; TGCT cis rs3540 0.554 rs12900987 chr15:91071776 T/C cg22089800 chr15:90895588 ZNF774 -0.75 -7.66 -0.57 4.62e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs11779988 0.545 rs422746 chr8:17784486 C/A cg01800426 chr8:17659068 MTUS1 -0.7 -5.46 -0.44 2.5e-7 Breast cancer; TGCT cis rs3751972 0.590 rs12051730 chr17:26266230 C/T cg02948944 chr17:26242737 NA -0.46 -5.55 -0.45 1.65e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs3809566 0.676 rs4775607 chr15:63328007 C/T cg08198488 chr15:63333792 TPM1 -0.34 -5.26 -0.43 6.02e-7 Platelet count; TGCT cis rs4824093 0.610 rs73441787 chr22:50269646 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.48 4.97 0.41 2.17e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9990333 0.562 rs12632706 chr3:195815594 C/T cg14488913 chr3:195402182 SDHAP2 -0.37 -4.64 -0.38 8.57e-6 Iron status biomarkers (transferrin levels);Iron status biomarkers (transferrin saturation); TGCT cis rs2019137 0.936 rs902696 chr2:113954879 G/T cg27425262 chr2:113953981 PSD4;LOC440839 0.52 8.03 0.59 6.32e-13 Lymphocyte counts; TGCT cis rs9677476 0.608 rs7606037 chr2:232054576 T/C cg07929768 chr2:232055508 NA 0.34 5.48 0.44 2.26e-7 Food antigen IgG levels; TGCT cis rs6121246 0.529 rs7261354 chr20:30202414 T/C cg18721089 chr20:30220636 NA -0.57 -6.19 -0.49 7.9e-9 Mean corpuscular hemoglobin; TGCT cis rs1801251 0.929 rs10933409 chr2:233629386 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs453301 0.500 rs7015336 chr8:8830720 G/A cg06636001 chr8:8085503 FLJ10661 0.76 6.26 0.49 5.85e-9 Joint mobility (Beighton score); TGCT cis rs10504229 0.683 rs16921814 chr8:58107421 A/T cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.962 rs4809462 chr20:61661560 A/G cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs4478858 0.735 rs10798842 chr1:31778648 A/G cg00250761 chr1:31883323 NA -0.27 -4.94 -0.41 2.43e-6 Alcohol dependence; TGCT cis rs933688 0.689 rs12697808 chr5:90605389 T/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.65 -5.55 -0.45 1.67e-7 Smoking behavior; TGCT cis rs710216 0.917 rs4660691 chr1:43417150 T/G cg03128534 chr1:43423976 SLC2A1 -0.58 -4.65 -0.39 8.48e-6 Red cell distribution width; TGCT cis rs2303745 0.589 rs6512179 chr19:17399105 T/C cg02221750 chr19:17393354 ANKLE1 -0.46 -5.87 -0.47 3.73e-8 Systemic lupus erythematosus; TGCT cis rs7829975 0.606 rs7837026 chr8:8801692 T/C cg08975724 chr8:8085496 FLJ10661 -0.55 -4.57 -0.38 1.15e-5 Mood instability; TGCT cis rs9976767 0.637 rs9784215 chr21:43823736 C/A cg23042151 chr21:43824109 UBASH3A -0.23 -5.14 -0.42 1.02e-6 Type 1 diabetes; TGCT cis rs9814567 0.896 rs6799110 chr3:134206749 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2153535 0.505 rs1335629 chr6:8491863 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7914558 0.966 rs56946876 chr10:104653545 T/C cg15744005 chr10:104629667 AS3MT -0.41 -5.09 -0.42 1.29e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs763121 0.853 rs9610986 chr22:39025277 T/C cg06022373 chr22:39101656 GTPBP1 0.78 7.44 0.56 1.48e-11 Menopause (age at onset); TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs991168 chr4:98928293 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs2688608 0.620 rs7080350 chr10:75577843 A/G cg13918328 chr10:52500089 ASAH2B -0.7 -7.21 -0.54 4.8e-11 Inflammatory bowel disease; TGCT cis rs4819052 0.851 rs9753963 chr21:46661437 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs7613875 0.600 rs2624848 chr3:50165101 T/C cg21659725 chr3:3221576 CRBN -0.71 -7.96 -0.58 9.31e-13 Body mass index; TGCT trans rs2727020 0.521 rs7131163 chr11:49574774 C/T cg11707556 chr5:10655725 ANKRD33B -0.42 -8.32 -0.6 1.37e-13 Coronary artery disease; TGCT cis rs9457247 0.967 rs86755 chr6:167403108 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs12497850 0.931 rs7430501 chr3:48890119 C/T cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs10464366 0.571 rs4723825 chr7:39157627 G/C cg15212455 chr7:39170539 POU6F2 0.3 6.63 0.51 9.08e-10 IgG glycosylation; TGCT cis rs62064224 0.614 rs2286645 chr17:30696292 C/T cg18200150 chr17:30822561 MYO1D 0.38 4.44 0.37 1.97e-5 Schizophrenia; TGCT cis rs7824557 0.569 rs10106207 chr8:11015338 C/T cg27411982 chr8:10470053 RP1L1 -0.21 -4.67 -0.39 7.77e-6 Retinal vascular caliber; TGCT cis rs9549367 0.713 rs3024744 chr13:113821477 A/C cg18105134 chr13:113819100 PROZ -0.47 -8.19 -0.59 2.73e-13 Platelet distribution width; TGCT cis rs4689388 0.926 rs10937719 chr4:6295322 C/G cg00701064 chr4:6280414 WFS1 0.37 4.48 0.37 1.65e-5 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs916888 0.779 rs430685 chr17:44859148 T/C cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7191700 0.836 rs28502009 chr16:11426541 G/A cg00044050 chr16:11439710 C16orf75 0.68 5.67 0.45 9.4e-8 Multiple sclerosis; TGCT cis rs2842992 0.830 rs1535475 chr6:160148935 T/C cg11366901 chr6:160182831 ACAT2 1.04 6.93 0.53 2.05e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs1218582 0.774 rs4845683 chr1:154877407 T/C cg09359103 chr1:154839909 KCNN3 -0.71 -15.31 -0.81 2.37e-30 Prostate cancer; TGCT trans rs13064411 0.542 rs11537650 chr3:113222036 G/A cg00307254 chr3:126706825 PLXNA1 0.34 6.78 0.52 4.36e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs11792861 0.781 rs11793272 chr9:111762102 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.69 0.39 6.99e-6 Menarche (age at onset); TGCT trans rs1005277 0.579 rs1548255 chr10:38417193 T/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.25 -0.71 1.16e-20 Extrinsic epigenetic age acceleration; TGCT cis rs11696501 0.688 rs6065861 chr20:44311056 A/G cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs7811142 0.830 rs73401451 chr7:99981895 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs3780378 0.967 rs7857730 chr9:5084049 G/T cg02405213 chr9:5042618 JAK2 -0.64 -8.62 -0.61 2.61e-14 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT trans rs916888 0.610 rs199444 chr17:44818276 T/C cg22433210 chr17:43662623 NA 0.96 7.89 0.58 1.39e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7208859 0.673 rs216435 chr17:28922737 G/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs77972916 0.505 rs6756575 chr2:43528519 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -5.68 -0.45 9.24e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs13108904 0.557 rs1250098 chr4:1238256 A/T cg19318889 chr4:1322082 MAEA -0.2 -4.91 -0.4 2.8e-6 Obesity-related traits; TGCT cis rs2692947 0.644 rs772154 chr2:97021664 G/T cg23100626 chr2:96804247 ASTL 0.41 4.97 0.41 2.22e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs860295 0.580 rs2016251 chr1:155914988 C/T cg05700447 chr1:155978627 NA 0.21 4.44 0.37 1.97e-5 Body mass index; TGCT cis rs12188164 0.930 rs72717436 chr5:448291 C/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs8192284 0.965 rs61812598 chr1:154420087 G/A cg11650704 chr1:154556575 ADAR 0.26 4.56 0.38 1.19e-5 Fibrinogen;C-reactive protein;Fibrinogen levels; TGCT cis rs16958440 0.867 rs57744138 chr18:44700482 A/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs9814567 1.000 rs9826496 chr3:134224437 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9341808 0.667 rs12209624 chr6:80919133 G/A cg08355045 chr6:80787529 NA 0.31 5.17 0.42 9.19e-7 Sitting height ratio; TGCT cis rs2228479 0.702 rs62056090 chr16:89930087 T/A cg06558623 chr16:89946397 TCF25 0.52 4.6 0.38 1.05e-5 Skin colour saturation; TGCT cis rs2562456 0.761 rs35008138 chr19:21731624 A/T cg25650185 chr19:21324782 ZNF431 -0.64 -5.73 -0.46 7.12e-8 Pain; TGCT cis rs478304 0.593 rs9666878 chr11:65475816 A/C cg17480646 chr11:65405466 SIPA1 0.61 8.04 0.59 6.16e-13 Acne (severe); TGCT cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.57 -5.68 -0.45 9.16e-8 Intelligence (multi-trait analysis); TGCT cis rs9399135 0.869 rs9402675 chr6:135325794 C/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg07330114 chr3:11624023 VGLL4 1.09 6.84 0.52 3.2e-10 Gambling; TGCT cis rs28595532 1.000 rs73842212 chr4:119638122 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.52 0.38 1.42e-5 Cannabis dependence symptom count; TGCT cis rs1577917 1.000 rs10455456 chr6:86670322 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs10504229 0.728 rs56180705 chr8:58149734 T/C cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs17030434 0.911 rs17030490 chr4:154738340 C/T cg14289246 chr4:154710475 SFRP2 -0.88 -7.09 -0.54 8.77e-11 Electrocardiographic conduction measures; TGCT trans rs1496653 0.602 rs75034324 chr3:23356795 T/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs1691799 0.899 rs1168317 chr12:66746225 C/T cg16791601 chr12:66731901 HELB -0.28 -6.18 -0.49 8.52e-9 White blood cell count (basophil); TGCT cis rs9486719 0.894 rs34826652 chr6:96899085 A/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7681440 0.904 rs58864428 chr4:90766986 T/C cg01966878 chr4:90757139 SNCA -0.25 -4.56 -0.38 1.2e-5 Dementia with Lewy bodies; TGCT cis rs2153535 0.580 rs9406172 chr6:8515464 T/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs7954584 0.616 rs10743185 chr12:122356435 G/A cg22618164 chr12:122356400 WDR66 0.53 5.18 0.42 8.83e-7 Mean corpuscular volume; TGCT cis rs35306767 0.953 rs12357633 chr10:957246 C/T cg20503657 chr10:835505 NA 0.74 10.28 0.68 2.58e-18 Eosinophil percentage of granulocytes; TGCT cis rs7659604 0.539 rs11731917 chr4:122783233 G/A cg20573242 chr4:122745356 CCNA2 0.63 5.54 0.45 1.72e-7 Type 2 diabetes; TGCT trans rs877282 0.898 rs11253343 chr10:765117 C/T cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs6952407 1 rs6952407 chr7:66045512 A/G cg18876405 chr7:65276391 NA -0.37 -5.57 -0.45 1.52e-7 Cotinine glucuronidation; TGCT cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg02018176 chr4:1364513 KIAA1530 0.27 4.59 0.38 1.07e-5 Longevity; TGCT cis rs6089584 1.000 rs6089580 chr20:60558976 G/A cg16423285 chr20:60520624 NA -0.52 -5.45 -0.44 2.6e-7 Body mass index; TGCT cis rs78487399 0.665 rs17030980 chr2:43751480 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.37 -4.63 -0.38 9.08e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6089829 0.888 rs4809468 chr20:61673566 T/C cg08045932 chr20:61659980 NA 0.5 8.72 0.62 1.54e-14 Prostate cancer (SNP x SNP interaction); TGCT trans rs459571 0.959 rs378740 chr9:136890876 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.71 -7.72 -0.57 3.29e-12 Platelet distribution width; TGCT cis rs727505 1.000 rs28392553 chr7:124442944 C/T cg23710748 chr7:124431027 NA -0.27 -4.62 -0.38 9.49e-6 Lewy body disease; TGCT cis rs11711311 1.000 rs9826808 chr3:113455644 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs3820928 0.874 rs13419455 chr2:227850465 C/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs4722166 0.630 rs7808457 chr7:22798265 A/T cg26061582 chr7:22766209 IL6 -0.47 -6.15 -0.48 9.68e-9 Lung cancer; TGCT cis rs4253772 0.591 rs9615938 chr22:46689468 G/A cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs4563143 0.514 rs73029079 chr19:29294903 A/G cg12756686 chr19:29218302 NA 0.67 5.16 0.42 9.34e-7 Methadone dose in opioid dependence; TGCT cis rs7659604 0.643 rs6839054 chr4:122663628 C/T cg06713675 chr4:122721982 EXOSC9 -0.45 -5.17 -0.42 9.22e-7 Type 2 diabetes; TGCT cis rs3784262 0.643 rs2453280 chr15:58368379 C/T cg12031962 chr15:58353849 ALDH1A2 0.4 5.72 0.46 7.56e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs3784262 0.669 rs4646626 chr15:58256127 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.11 -0.48 1.19e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6671200 1.000 rs34037437 chr1:95660921 C/G cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs28595532 0.920 rs115259971 chr4:119762654 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4074961 0.669 rs6687545 chr1:38071195 C/T cg11397548 chr1:38022522 DNALI1 0.43 4.78 0.39 4.95e-6 Axial length; TGCT cis rs67478160 0.643 rs2295141 chr14:104212949 T/C cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs3733585 0.699 rs6844787 chr4:9959233 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7246657 0.678 rs4802024 chr19:38052193 T/C cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs2549003 1.000 rs2070727 chr5:131820275 C/A cg02551604 chr5:131831745 NA -0.89 -11.95 -0.73 2.33e-22 Asthma (sex interaction); TGCT cis rs6665290 0.904 rs3795451 chr1:227181923 C/T cg10327440 chr1:227177885 CDC42BPA -0.98 -19.78 -0.87 3.72e-40 Myeloid white cell count; TGCT cis rs12497850 0.931 rs7647813 chr3:48833348 G/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs208515 0.525 rs9453538 chr6:66668508 G/A cg07460842 chr6:66804631 NA 0.85 8.73 0.62 1.41e-14 Exhaled nitric oxide levels; TGCT cis rs4665809 1.000 rs6546727 chr2:26275282 C/T cg25036284 chr2:26402008 FAM59B -0.57 -5.0 -0.41 1.94e-6 Gut microbiome composition (summer); TGCT cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg20607798 chr8:58055168 NA 0.62 5.23 0.43 6.99e-7 Developmental language disorder (linguistic errors); TGCT cis rs453301 0.686 rs4840389 chr8:8884503 G/C cg11995313 chr8:8860691 ERI1 0.54 4.73 0.39 6.09e-6 Joint mobility (Beighton score); TGCT cis rs6582630 0.555 rs10880613 chr12:38509553 C/T cg13010199 chr12:38710504 ALG10B 0.64 5.15 0.42 9.97e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs986417 0.818 rs2351173 chr14:61008755 C/T cg27398547 chr14:60952738 C14orf39 1.49 10.43 0.68 1.12e-18 Gut microbiota (bacterial taxa); TGCT cis rs2228479 0.850 rs62056102 chr16:89941438 T/C cg06558623 chr16:89946397 TCF25 0.62 7.04 0.53 1.19e-10 Skin colour saturation; TGCT cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg12437481 chr16:420112 MRPL28 -0.52 -5.17 -0.42 9.01e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs9467773 1.000 rs1884949 chr6:26568067 G/A cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 -0.78 -5.65 -0.45 1.03e-7 Platelet count; TGCT cis rs3820068 0.581 rs6692461 chr1:15928449 A/G cg05660106 chr1:15850417 CASP9 0.74 7.27 0.55 3.53e-11 Systolic blood pressure; TGCT cis rs858239 0.601 rs10278776 chr7:23169759 C/T cg05602783 chr7:23145260 KLHL7 -0.65 -5.48 -0.44 2.32e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6424115 0.965 rs2502979 chr1:24149315 C/A cg15997130 chr1:24165203 NA 0.92 10.57 0.69 5.26e-19 Immature fraction of reticulocytes; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg11115673 chr10:50224628 C10orf72 -0.83 -7.11 -0.54 8.21e-11 Follicular lymphoma; TGCT cis rs9990333 0.526 rs11719682 chr3:195834202 C/T cg14488913 chr3:195402182 SDHAP2 -0.35 -4.47 -0.37 1.71e-5 Iron status biomarkers (transferrin levels);Iron status biomarkers (transferrin saturation); TGCT cis rs76473307 1.000 rs117182713 chr20:57379444 G/A cg06163629 chr20:57414884 GNASAS;GNAS -0.66 -4.53 -0.38 1.39e-5 Chronic lymphocytic leukemia; TGCT cis rs13242816 1.000 rs13243017 chr7:116189371 G/A cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs554111 0.634 rs4654875 chr1:21165176 A/G cg01072550 chr1:21505969 NA 0.33 4.94 0.41 2.43e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs7611238 0.520 rs9848201 chr3:195098843 A/T cg27323046 chr3:195102265 ACAP2 0.39 5.11 0.42 1.18e-6 Body mass index; TGCT cis rs2073300 1.000 rs6132626 chr20:23444672 T/C cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7923609 0.967 rs6479896 chr10:65126832 T/C cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.14e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs3540 0.597 rs7498113 chr15:91051192 C/G cg22089800 chr15:90895588 ZNF774 -0.76 -7.96 -0.58 9.42e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7267979 0.833 rs4619688 chr20:25244101 C/G cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.95e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13108904 0.870 rs1960426 chr4:1274365 C/T cg03303774 chr4:1407052 NA 0.32 5.03 0.41 1.69e-6 Obesity-related traits; TGCT cis rs12497850 0.931 rs9840050 chr3:49133310 A/G cg07636037 chr3:49044803 WDR6 0.96 10.9 0.7 8.39e-20 Parkinson's disease; TGCT cis rs5750830 0.621 rs743838 chr22:39824707 T/G cg11247378 chr22:39784982 NA -0.73 -9.83 -0.66 3.22e-17 Intelligence (multi-trait analysis); TGCT cis rs2180341 1.000 rs3798853 chr6:127636823 C/T cg24812749 chr6:127587940 RNF146 -0.96 -7.45 -0.56 1.42e-11 Breast cancer; TGCT cis rs7267979 0.753 rs404148 chr20:25447931 A/G cg13486641 chr20:25479848 NINL -0.16 -4.54 -0.38 1.32e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1008375 0.932 rs6841784 chr4:17626418 G/A cg16339924 chr4:17578868 LAP3 0.71 5.7 0.46 8.2e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9473924 0.542 rs9473946 chr6:50892950 G/A cg14470998 chr6:50812995 TFAP2B 1.35 8.21 0.59 2.48e-13 Body mass index; TGCT cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs3820068 0.603 rs998032 chr1:15989918 T/C cg05660106 chr1:15850417 CASP9 0.81 7.67 0.57 4.28e-12 Systolic blood pressure; TGCT cis rs7226408 0.857 rs72888926 chr18:34530957 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs394563 0.591 rs6570963 chr6:149691355 T/G cg03678062 chr6:149772716 ZC3H12D 0.38 4.8 0.4 4.4e-6 Dupuytren's disease; TGCT cis rs78456975 0.527 rs10203194 chr2:1558021 A/G cg01028140 chr2:1542097 TPO -0.33 -5.12 -0.42 1.14e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs1008375 1.000 rs9991307 chr4:17662408 A/G cg18681998 chr4:17616180 MED28 0.94 11.11 0.71 2.57e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6964587 0.692 rs2299233 chr7:91626953 C/T cg17063962 chr7:91808500 NA -0.73 -6.97 -0.53 1.68e-10 Breast cancer; TGCT cis rs7246657 0.722 rs2075284 chr19:38189616 T/C cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs3820068 0.608 rs9660255 chr1:16031891 T/G cg17385448 chr1:15911702 AGMAT 0.34 4.78 0.39 4.97e-6 Systolic blood pressure; TGCT cis rs3806843 1.000 rs10037757 chr5:140197222 G/T cg19875535 chr5:140030758 IK 0.35 5.73 0.46 7.12e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9326248 0.954 rs521171 chr11:117064693 C/G cg16524733 chr11:117070046 TAGLN 0.33 4.9 0.4 2.98e-6 Blood protein levels; TGCT cis rs4665809 0.549 rs34075014 chr2:26520842 T/C cg25036284 chr2:26402008 FAM59B 0.67 4.46 0.37 1.79e-5 Gut microbiome composition (summer); TGCT trans rs8073060 0.859 rs17550268 chr17:33874678 T/C cg19694781 chr19:47549865 TMEM160 0.53 10.2 0.68 4.19e-18 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs13401104 0.587 rs56146026 chr2:237145629 A/G cg26422059 chr2:237146110 ASB18 0.57 4.56 0.38 1.19e-5 Educational attainment; TGCT cis rs7267979 0.808 rs84816 chr20:25459919 G/A cg03522245 chr20:25566470 NINL 0.6 6.37 0.5 3.35e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2191566 0.960 rs12232810 chr19:44525122 A/G cg03039196 chr19:44506973 ZNF230 0.53 4.48 0.37 1.7e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs7973719 0.865 rs12820829 chr12:7347534 G/A cg07052231 chr12:7363540 PEX5 0.37 5.68 0.45 9.04e-8 IgG glycosylation; TGCT trans rs7618501 0.815 rs3819325 chr3:49843723 T/C cg21659725 chr3:3221576 CRBN 0.99 15.51 0.81 8.11e-31 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.765 rs727563 chr22:41867377 C/T cg13695892 chr22:41940480 POLR3H 0.86 8.61 0.61 2.75e-14 Vitiligo; TGCT cis rs7588746 0.544 rs2163548 chr2:201226862 C/G cg19045956 chr2:200819837 C2orf60;C2orf47 -0.64 -4.5 -0.37 1.56e-5 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs12893668 0.608 rs12889721 chr14:104034863 C/T cg26031613 chr14:104095156 KLC1 -0.54 -4.45 -0.37 1.88e-5 Reticulocyte count; TGCT cis rs2463822 0.844 rs72923263 chr11:62161170 C/G cg06239285 chr11:62104954 ASRGL1 -0.85 -5.54 -0.45 1.76e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6088580 0.634 rs6058041 chr20:33018008 A/G cg08999081 chr20:33150536 PIGU 0.28 5.52 0.44 1.89e-7 Glomerular filtration rate (creatinine); TGCT cis rs10992471 0.756 rs10992303 chr9:95082804 A/G cg14631576 chr9:95140430 CENPP -0.29 -4.72 -0.39 6.22e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12049351 0.774 rs35464914 chr1:229690232 C/T cg12130225 chr1:229698885 NA 0.38 4.63 0.38 8.95e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs7429990 0.786 rs11919665 chr3:48085349 A/T cg11946769 chr3:48343235 NME6 -0.52 -4.44 -0.37 1.95e-5 Educational attainment (years of education); TGCT cis rs7605378 0.688 rs769961 chr2:200712141 C/A cg19045956 chr2:200819837 C2orf60;C2orf47 0.5 4.72 0.39 6.17e-6 Osteoporosis; TGCT cis rs9733 0.596 rs3087960 chr1:150620569 C/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.51 0.38 1.5e-5 Tonsillectomy; TGCT cis rs11123170 0.529 rs1015755 chr2:113968307 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.54 4.51 0.38 1.5e-5 Renal function-related traits (BUN); TGCT cis rs2839186 0.771 rs13046451 chr21:47641373 T/A cg13732083 chr21:47605072 C21orf56 -0.37 -4.69 -0.39 7.07e-6 Testicular germ cell tumor; TGCT cis rs9303401 0.659 rs16943176 chr17:56769887 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs36051895 0.632 rs7030853 chr9:5179002 C/T cg02405213 chr9:5042618 JAK2 -0.74 -10.54 -0.69 6.32e-19 Pediatric autoimmune diseases; TGCT cis rs9560113 0.881 rs9560111 chr13:112181289 C/T cg14154082 chr13:112174009 NA 0.38 5.01 0.41 1.83e-6 Menarche (age at onset); TGCT cis rs7072216 0.763 rs2147900 chr10:100174721 T/C cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs9616064 0.813 rs9627512 chr22:46977702 C/T cg12346269 chr22:46322472 WNT7B 0.22 4.55 0.38 1.24e-5 Urate levels in obese individuals; TGCT cis rs8038465 0.622 rs710086 chr15:73877001 C/T cg15420318 chr15:73925796 NPTN 0.64 6.76 0.52 4.83e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2580764 0.566 rs2972072 chr2:55295370 G/T cg09592903 chr2:55203963 RTN4 0.25 5.79 0.46 5.55e-8 Mean platelet volume; TGCT cis rs1801251 0.929 rs10933409 chr2:233629386 A/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs2249625 0.545 rs2463743 chr6:72874741 C/T cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg20607798 chr8:58055168 NA 0.61 5.06 0.41 1.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.791 rs441290 chr6:145883183 A/G cg23711669 chr6:146136114 FBXO30 0.84 8.78 0.62 1.07e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.967 rs9467775 chr6:26513435 G/A cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs3824867 0.879 rs10742806 chr11:47456226 T/A cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs735396 0.770 rs2259820 chr12:121435342 C/T cg02403541 chr12:121454288 C12orf43 0.76 7.54 0.56 8.67e-12 N-glycan levels; TGCT cis rs921968 0.643 rs492400 chr2:219349752 C/T cg02176678 chr2:219576539 TTLL4 0.42 6.17 0.48 8.99e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs5750830 0.649 rs4384886 chr22:39793766 C/T cg02038168 chr22:39784481 NA -0.78 -6.7 -0.52 6.48e-10 Intelligence (multi-trait analysis); TGCT cis rs1395 0.922 rs1561535 chr2:27471025 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.48 6.25 0.49 6.03e-9 Blood metabolite levels; TGCT cis rs637571 0.510 rs12575663 chr11:65574535 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.67 -6.01 -0.48 1.9e-8 Eosinophil percentage of white cells; TGCT cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg06634786 chr22:41940651 POLR3H -0.86 -7.8 -0.57 2.13e-12 Vitiligo; TGCT cis rs11190604 1.000 rs7080356 chr10:102266735 A/C cg23241863 chr10:102295624 HIF1AN 0.7 5.38 0.43 3.59e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12544026 0.581 rs472963 chr8:102863119 A/G cg01952226 chr8:102507382 GRHL2 -0.27 -4.54 -0.38 1.31e-5 Major depression and alcohol dependence; TGCT cis rs394563 0.591 rs237012 chr6:149729198 T/C cg03678062 chr6:149772716 ZC3H12D -0.38 -4.74 -0.39 5.83e-6 Dupuytren's disease; TGCT cis rs7010267 0.596 rs7010043 chr8:120011331 G/T cg17171407 chr8:119960777 TNFRSF11B 0.28 5.09 0.42 1.27e-6 Total body bone mineral density (age 45-60); TGCT cis rs903263 0.870 rs2134649 chr1:84662712 T/G cg09664975 chr1:84543551 PRKACB 0.47 4.48 0.37 1.65e-5 Breast cancer (male); TGCT cis rs7772486 0.875 rs10872582 chr6:146373061 G/A cg23711669 chr6:146136114 FBXO30 0.85 9.15 0.63 1.47e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2456568 0.803 rs10831138 chr11:93640468 T/C cg26875233 chr11:93583750 C11orf90 -0.48 -6.35 -0.5 3.73e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs35306767 0.855 rs12781100 chr10:838636 C/T cg26597838 chr10:835615 NA 0.81 12.25 0.74 4.2e-23 Eosinophil percentage of granulocytes; TGCT cis rs6690583 0.623 rs6700723 chr1:85514234 C/T cg20280350 chr1:85513789 MCOLN3 -0.79 -4.9 -0.4 2.9e-6 Serum sulfate level; TGCT cis rs5769707 0.967 rs12485195 chr22:50053871 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.54 0.38 1.32e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs72945132 0.882 rs72945168 chr11:70131471 G/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7666738 0.830 rs62321565 chr4:98976571 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs5769707 0.967 rs9616701 chr22:50025546 G/A cg10356904 chr22:49881777 NA -0.22 -4.52 -0.38 1.4e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs4665809 0.941 rs41285975 chr2:26351144 T/C cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs11673344 0.504 rs4806408 chr19:37588777 C/T cg08039142 chr19:36980659 ZNF566 0.52 4.86 0.4 3.48e-6 Obesity-related traits; TGCT cis rs10791097 0.967 rs6590512 chr11:130717916 A/G cg12179176 chr11:130786555 SNX19 -0.63 -6.43 -0.5 2.52e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11249608 0.548 rs10516150 chr5:178459169 G/C cg01312482 chr5:178451176 ZNF879 -0.49 -4.85 -0.4 3.62e-6 Pubertal anthropometrics; TGCT cis rs7599312 0.534 rs10207878 chr2:213409337 A/G cg16329650 chr2:213403929 ERBB4 1.07 15.96 0.82 7.41e-32 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs739401 0.572 rs739399 chr11:3016452 A/G cg25174290 chr11:3078921 CARS 0.5 4.75 0.39 5.54e-6 Longevity; TGCT cis rs9372498 0.536 rs62422228 chr6:118957276 T/C cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs806215 1.000 rs712697 chr7:127247132 T/A cg25922125 chr7:127225783 GCC1 0.59 5.98 0.47 2.21e-8 Type 2 diabetes; TGCT cis rs2692947 0.537 rs11164049 chr2:96345518 C/T cg23100626 chr2:96804247 ASTL 0.42 5.29 0.43 5.37e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9921338 0.886 rs3931015 chr16:11415639 G/A cg00044050 chr16:11439710 C16orf75 0.95 7.39 0.55 1.92e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs7552404 1.000 rs4949876 chr1:76173377 C/T cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4689388 0.853 rs6446479 chr4:6291737 G/C cg25554036 chr4:6271136 WFS1 0.55 7.59 0.56 6.58e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs765787 0.530 rs12592055 chr15:45514477 C/T cg24006582 chr15:45444508 DUOX1 0.25 5.44 0.44 2.7e-7 Uric acid levels; TGCT cis rs9467711 1.000 rs9467701 chr6:26312170 G/C cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12579753 0.871 rs10862363 chr12:82201254 T/A cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs10089 1.000 rs10060181 chr5:127475573 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.53 0.56 9.3e-12 Ileal carcinoids; TGCT cis rs2721195 0.781 rs10110962 chr8:145780323 C/T cg17328964 chr8:145687451 CYHR1 -0.43 -5.94 -0.47 2.68e-8 Age at first birth; TGCT cis rs1799949 0.965 rs4793234 chr17:41436183 A/G cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 3.03e-27 Menopause (age at onset); TGCT cis rs9325144 0.560 rs13377717 chr12:38639474 T/A cg26384229 chr12:38710491 ALG10B -0.65 -6.12 -0.48 1.13e-8 Morning vs. evening chronotype; TGCT cis rs4299518 0.739 rs17279465 chr3:45814748 C/T cg04837898 chr3:45731254 SACM1L 0.47 4.52 0.38 1.41e-5 Hirschsprung disease; TGCT cis rs4523957 0.620 rs9912385 chr17:2062591 T/G cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs10435719 0.528 rs13250020 chr8:11789769 A/G cg15556689 chr8:8085844 FLJ10661 0.73 6.89 0.53 2.55e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs7582180 0.817 rs1437967 chr2:100929072 C/G cg14675211 chr2:100938903 LONRF2 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs1857353 1.000 rs4540592 chr1:75883281 C/T cg11838876 chr1:75668600 SLC44A5 0.51 4.81 0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs16866061 1.000 rs11694987 chr2:225397409 C/G cg12698349 chr2:225449008 CUL3 0.95 8.97 0.63 3.83e-15 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs36405 0.957 rs36411 chr14:72356551 A/G cg10066683 chr14:71515513 PCNX 0.24 4.7 0.39 6.69e-6 Yang-deficiency constitution; TGCT cis rs8064299 0.655 rs11655219 chr17:72771293 C/T cg25054828 chr17:72772726 NAT9;TMEM104 0.6 5.45 0.44 2.56e-7 Monocyte count; TGCT cis rs9611565 0.559 rs5758428 chr22:42106216 G/A cg13695892 chr22:41940480 POLR3H 0.88 8.63 0.61 2.45e-14 Vitiligo; TGCT trans rs608114 0.793 rs656756 chr6:96380686 G/A cg04008557 chr11:2826328 KCNQ1 -0.65 -6.82 -0.52 3.51e-10 Response to abacavir-containing treatment in HIV-1 infection (virologic failure);Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs1005224 1.000 rs1005224 chr14:76173860 A/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.7 -6.12 -0.48 1.14e-8 Large artery stroke; TGCT cis rs9467773 0.620 rs6925087 chr6:26592853 T/A cg26531700 chr6:26746687 NA 0.5 4.65 0.39 8.29e-6 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs514406 0.698 rs1775540 chr1:53407893 C/A cg16325326 chr1:53192061 ZYG11B 0.5 5.59 0.45 1.38e-7 Monocyte count; TGCT cis rs35828350 1 rs35828350 chr15:85355841 G/A cg17173187 chr15:85201210 NMB 0.56 6.32 0.49 4.23e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg06481639 chr22:41940642 POLR3H -0.62 -5.61 -0.45 1.25e-7 Vitiligo; TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 15.18 0.81 4.71e-30 Prudent dietary pattern; TGCT cis rs3892630 0.817 rs35408716 chr19:33187961 A/C cg22980127 chr19:33182716 NUDT19 0.7 5.18 0.42 8.9e-7 Red blood cell traits; TGCT cis rs12780845 0.540 rs12770238 chr10:17209570 C/G cg01003015 chr10:17271136 VIM 0.54 4.78 0.39 4.87e-6 Homocysteine levels; TGCT cis rs9611565 0.559 rs132761 chr22:42004371 C/T cg06481639 chr22:41940642 POLR3H 0.74 6.64 0.51 8.88e-10 Vitiligo; TGCT cis rs12497850 0.865 rs13072911 chr3:48962128 T/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs912330 0.529 rs4772100 chr13:99196573 G/T cg07423050 chr13:99094983 FARP1 -0.24 -5.19 -0.42 8.43e-7 Alzheimer's disease; TGCT cis rs644799 0.710 rs11021309 chr11:95501898 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.29 0.6 1.54e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9486719 0.947 rs12210834 chr6:96890407 A/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs367615 0.842 rs2578484 chr5:108950808 G/A cg17395555 chr5:108820864 NA -0.29 -4.89 -0.4 3.09e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1129187 0.755 rs9471982 chr6:42935998 G/A cg02353165 chr6:42928485 GNMT 0.97 9.95 0.67 1.66e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9325144 0.647 rs7957185 chr12:38909710 G/A cg26384229 chr12:38710491 ALG10B -0.56 -4.87 -0.4 3.34e-6 Morning vs. evening chronotype; TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg10263370 chr3:44754102 ZNF502 -0.42 -5.03 -0.41 1.65e-6 Depressive symptoms; TGCT cis rs7681440 0.935 rs3756059 chr4:90757272 G/A cg26578617 chr4:90757533 SNCA -0.48 -4.95 -0.41 2.33e-6 Dementia with Lewy bodies; TGCT cis rs8017423 1.000 rs8015379 chr14:90679432 C/T cg04374321 chr14:90722782 PSMC1 0.77 7.94 0.58 1.06e-12 Mortality in heart failure; TGCT cis rs4601821 0.823 rs4938015 chr11:113264644 C/T cg14159747 chr11:113255604 NA -0.4 -5.11 -0.42 1.17e-6 Alcoholic chronic pancreatitis; TGCT cis rs3760982 0.585 rs10422108 chr19:44294868 C/T cg12072164 chr19:44306565 LYPD5 0.3 4.45 0.37 1.86e-5 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs9916302 0.861 rs10491129 chr17:37461643 T/G cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg26118208 chr10:134322334 NA 0.27 5.13 0.42 1.08e-6 Migraine; TGCT cis rs8180040 0.932 rs1531875 chr3:47452786 G/A cg27129171 chr3:47204927 SETD2 0.65 7.74 0.57 2.99e-12 Colorectal cancer; TGCT cis rs9611519 0.754 rs4820435 chr22:41652846 G/T cg06634786 chr22:41940651 POLR3H -0.59 -5.45 -0.44 2.56e-7 Neuroticism; TGCT cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg11494091 chr17:61959527 GH2 0.42 7.33 0.55 2.54e-11 Height; TGCT cis rs36051895 0.695 rs62541534 chr9:5028921 C/G cg02405213 chr9:5042618 JAK2 -0.77 -10.43 -0.68 1.16e-18 Pediatric autoimmune diseases; TGCT cis rs7225537 0.559 rs7214429 chr17:17059872 A/G cg26176665 chr17:16994978 MPRIP -0.24 -5.54 -0.45 1.74e-7 Mean platelet volume; TGCT cis rs10986311 0.862 rs1408096 chr9:127107143 C/G cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.55 0.38 1.28e-5 Vitiligo; TGCT cis rs7267979 0.932 rs1541061 chr20:25521057 G/A cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2243480 0.901 rs3813708 chr7:65305632 C/A cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs4499344 0.730 rs7246338 chr19:33099504 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 8.76 0.62 1.23e-14 Mean platelet volume; TGCT cis rs73198271 0.740 rs10113326 chr8:8647630 A/T cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9916302 0.800 rs8069451 chr17:37504933 C/T cg07936489 chr17:37558343 FBXL20 -0.59 -4.6 -0.38 1.04e-5 Glomerular filtration rate (creatinine); TGCT cis rs6964587 0.934 rs7811328 chr7:91720931 A/T cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs909674 0.731 rs4821897 chr22:39835587 A/G cg11247378 chr22:39784982 NA -0.74 -8.7 -0.62 1.65e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9549367 0.789 rs9549698 chr13:113877701 A/G cg00898013 chr13:113819073 PROZ -0.42 -5.12 -0.42 1.15e-6 Platelet distribution width; TGCT cis rs916888 0.773 rs199445 chr17:44817408 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.64 -5.6 -0.45 1.32e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3772130 0.923 rs34865234 chr3:121560995 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs478304 0.651 rs4930312 chr11:65499719 G/A cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.05e-10 Acne (severe); TGCT cis rs17376456 0.757 rs10476591 chr5:93333723 G/C cg09848695 chr5:92956644 FAM172A;MIR2277 0.64 4.6 0.38 1.03e-5 Diabetic retinopathy; TGCT cis rs6912958 0.712 rs4707383 chr6:88330602 T/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs4727027 0.800 rs10952796 chr7:148813138 G/C cg23583168 chr7:148888333 NA -0.72 -9.16 -0.64 1.34e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9913156 0.841 rs72824957 chr17:4590496 C/T cg23387401 chr17:4582204 PELP1 0.31 4.68 0.39 7.44e-6 Lymphocyte counts; TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs9796 0.870 rs2306083 chr15:41347658 C/T cg18705301 chr15:41695430 NDUFAF1 -0.42 -5.42 -0.44 2.92e-7 Menopause (age at onset); TGCT cis rs1153858 1.000 rs2461701 chr15:45703391 G/A cg26924012 chr15:45694286 SPATA5L1 0.99 12.38 0.74 2.11e-23 Homoarginine levels; TGCT cis rs7666738 0.830 rs17027216 chr4:99009152 G/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4713675 0.649 rs568901 chr6:33710038 A/G cg13859433 chr6:33739653 LEMD2 0.3 5.02 0.41 1.73e-6 Plateletcrit; TGCT cis rs6693567 0.565 rs471657 chr1:150276461 G/A cg09579323 chr1:150459698 TARS2 -0.52 -4.64 -0.38 8.63e-6 Migraine; TGCT cis rs3796352 1.000 rs6445557 chr3:53083969 C/T cg27565382 chr3:53032988 SFMBT1 -0.41 -4.61 -0.38 9.92e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4305276 0.557 rs7607996 chr2:241470735 T/C cg21930842 chr2:241631663 AQP12A -0.27 -4.72 -0.39 6.38e-6 Mean platelet volume; TGCT cis rs514406 0.505 rs395169 chr1:53174071 G/A cg22166914 chr1:53195759 ZYG11B 0.45 7.9 0.58 1.29e-12 Monocyte count; TGCT cis rs7618915 0.571 rs11130307 chr3:52607682 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs10488031 0.850 rs13243420 chr7:37064595 G/A cg06458904 chr7:36312573 EEPD1 0.56 4.74 0.39 5.8e-6 QT interval; TGCT cis rs3093024 0.935 rs10946216 chr6:167538897 T/C cg07741184 chr6:167504864 NA -0.24 -4.85 -0.4 3.6e-6 Rheumatoid arthritis; TGCT cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs7654585 0.645 rs1123943 chr4:25924426 A/G cg10409131 chr4:25915609 C4orf52 -0.7 -6.82 -0.52 3.57e-10 Obesity-related traits; TGCT cis rs3091242 0.933 rs10903130 chr1:25769221 A/T cg09222892 chr1:25734099 RHCE -0.42 -7.15 -0.54 6.72e-11 Erythrocyte sedimentation rate; TGCT cis rs208520 0.690 rs12192710 chr6:66718137 C/T cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs4253772 0.637 rs6008339 chr22:46650846 C/T cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs875971 0.964 rs778723 chr7:65829497 T/C cg11764359 chr7:65958608 NA 0.6 5.31 0.43 4.78e-7 Aortic root size; TGCT cis rs36051895 0.593 rs12340303 chr9:5176147 C/T cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.2e-20 Pediatric autoimmune diseases; TGCT cis rs4654899 0.785 rs12070677 chr1:21337322 A/G cg01072550 chr1:21505969 NA -0.54 -8.69 -0.62 1.82e-14 Superior frontal gyrus grey matter volume; TGCT cis rs17030434 0.906 rs78436201 chr4:154661755 C/A cg14289246 chr4:154710475 SFRP2 -0.88 -7.14 -0.54 6.93e-11 Electrocardiographic conduction measures; TGCT cis rs12477438 0.605 rs4585080 chr2:99557327 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.62 -5.33 -0.43 4.48e-7 Chronic sinus infection; TGCT cis rs4776059 1.000 rs4776068 chr15:52947401 G/A cg25063058 chr15:52860530 ARPP19 0.54 4.86 0.4 3.43e-6 Schizophrenia; TGCT cis rs2439831 0.681 rs2242067 chr15:43699303 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.82 4.7 0.39 6.71e-6 Lung cancer in ever smokers; TGCT cis rs3087591 0.708 rs17885030 chr17:29655218 C/T cg24425628 chr17:29625626 OMG;NF1 0.39 5.46 0.44 2.45e-7 Hip circumference; TGCT cis rs11122272 0.735 rs971534 chr1:231521971 C/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs1334894 0.892 rs72913412 chr6:35536654 G/A cg24281267 chr6:35479648 TULP1 -0.43 -4.49 -0.37 1.63e-5 Coronary artery disease; TGCT cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg13342137 chr4:2252803 MXD4 0.16 4.46 0.37 1.79e-5 Obesity-related traits; TGCT cis rs910316 1.000 rs12897094 chr14:75579416 C/T cg11812906 chr14:75593930 NEK9 0.75 7.4 0.55 1.77e-11 Height; TGCT trans rs34421088 0.560 rs2467520 chr8:11398953 T/C cg15556689 chr8:8085844 FLJ10661 -0.75 -7.02 -0.53 1.28e-10 Neuroticism; TGCT cis rs854765 0.547 rs2955355 chr17:17948475 G/A cg04398451 chr17:18023971 MYO15A 0.33 5.37 0.43 3.76e-7 Total body bone mineral density; TGCT cis rs5769765 1.000 rs5770728 chr22:50259984 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.71 0.72 8.52e-22 Schizophrenia; TGCT cis rs2067615 0.579 rs12312782 chr12:107135647 G/A cg15890332 chr12:107067104 RFX4 0.3 5.93 0.47 2.85e-8 Heart rate; TGCT cis rs9303401 0.580 rs2013166 chr17:56637630 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs854624 0.892 rs2702954 chr17:34334738 C/T cg02022384 chr17:34097390 MMP28 0.5 4.67 0.39 7.74e-6 Blood protein levels; TGCT cis rs492146 0.819 rs677636 chr6:52837307 G/A cg06706454 chr6:52930286 FBXO9 -0.5 -4.63 -0.38 9.12e-6 Epilepsy (remission after treatment); TGCT cis rs9527 0.590 rs7912517 chr10:104905529 G/A cg04362960 chr10:104952993 NT5C2 0.65 5.59 0.45 1.36e-7 Arsenic metabolism; TGCT cis rs10744422 0.764 rs7957643 chr12:123296118 G/A cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg08859206 chr1:53392774 SCP2 0.41 5.98 0.47 2.19e-8 Monocyte count; TGCT cis rs9581857 0.512 rs9652091 chr13:28073509 G/A cg22138327 chr13:27999177 GTF3A 0.83 5.89 0.47 3.44e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg05552183 chr6:42928497 GNMT 0.52 4.55 0.38 1.25e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7249142 0.526 rs7256811 chr19:19283551 A/G cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.55 0.45 1.64e-7 IgG glycosylation; TGCT cis rs7714584 1.000 rs7705542 chr5:150228318 G/A cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs42648 0.869 rs42609 chr7:89949855 A/T cg25739043 chr7:89950458 NA -0.73 -7.29 -0.55 3.2e-11 Homocysteine levels; TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg25767906 chr1:53392781 SCP2 0.6 7.04 0.53 1.15e-10 Monocyte count; TGCT cis rs6582630 0.537 rs66855609 chr12:38299029 T/C cg26384229 chr12:38710491 ALG10B 0.77 6.88 0.53 2.6200000000000003e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs854765 0.964 rs2230316 chr17:17997209 C/T cg09796270 chr17:17721594 SREBF1 -0.25 -4.85 -0.4 3.6e-6 Total body bone mineral density; TGCT cis rs854765 0.618 rs9908017 chr17:17774422 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.75 -7.78 -0.57 2.42e-12 Total body bone mineral density; TGCT cis rs9653442 0.648 rs11123805 chr2:100643464 A/G cg07810366 chr2:100720526 AFF3 -0.4 -6.6 -0.51 1.06e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10193935 0.605 rs10169492 chr2:42401961 G/T cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6460942 0.908 rs6978857 chr7:12232665 A/G cg06484146 chr7:12443880 VWDE -0.52 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs6688613 1.000 rs6656999 chr1:166956807 C/G cg07049167 chr1:166818506 POGK 0.21 4.5 0.37 1.57e-5 Refractive astigmatism; TGCT cis rs10464366 1.000 rs10951593 chr7:39121390 C/T cg15212455 chr7:39170539 POU6F2 0.23 5.06 0.41 1.49e-6 IgG glycosylation; TGCT cis rs6543140 0.601 rs6543135 chr2:103062406 C/T cg09003973 chr2:102972529 NA 0.79 6.41 0.5 2.77e-9 Blood protein levels; TGCT cis rs7412746 0.658 rs2089082 chr1:150800090 T/G cg04414720 chr1:150670196 GOLPH3L 0.38 4.69 0.39 7.01e-6 Melanoma; TGCT cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs68170813 0.559 rs80307895 chr7:106907781 T/A cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs739496 0.579 rs11066046 chr12:112283881 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs6429082 0.755 rs291370 chr1:235693041 A/G cg26050004 chr1:235667680 B3GALNT2 0.66 6.23 0.49 6.65e-9 Adiposity; TGCT cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg26531700 chr6:26746687 NA 0.51 4.64 0.38 8.75e-6 Intelligence (multi-trait analysis); TGCT trans rs1864729 1.000 rs2028480 chr8:98290358 C/G cg08679828 chr8:102218111 ZNF706 -1.08 -7.55 -0.56 8.16e-12 Estradiol plasma levels (breast cancer); TGCT cis rs4727027 0.933 rs7788925 chr7:148831621 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4665809 0.590 rs2384361 chr2:26452209 T/C cg04944784 chr2:26401820 FAM59B -0.77 -6.36 -0.5 3.61e-9 Gut microbiome composition (summer); TGCT cis rs7568458 0.837 rs3770098 chr2:85805367 C/A cg17127132 chr2:85788382 GGCX 0.72 6.68 0.51 7.18e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs12908161 0.959 rs62019472 chr15:85331493 A/G cg17173187 chr15:85201210 NMB 0.55 6.11 0.48 1.17e-8 Schizophrenia; TGCT cis rs8013055 0.846 rs10139300 chr14:105974501 A/G cg23356831 chr14:105996513 TMEM121 0.41 6.33 0.49 4.01e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs3935685 0.874 rs4595768 chr15:78006290 C/T cg03457338 chr15:78040120 NA -0.23 -5.78 -0.46 5.72e-8 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.614 rs2060459 chr8:11212599 C/T cg21775007 chr8:11205619 TDH 0.71 6.81 0.52 3.8e-10 Retinal vascular caliber; TGCT cis rs4665809 1.000 rs2891490 chr2:26325927 T/C cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs10744422 1.000 rs7294991 chr12:123286780 C/T cg25930673 chr12:123319894 HIP1R -0.81 -4.63 -0.38 9.1e-6 Schizophrenia; TGCT cis rs6570726 0.791 rs6570695 chr6:145911286 C/A cg05347473 chr6:146136440 FBXO30 0.51 4.75 0.39 5.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs929596 0.785 rs17862875 chr2:234649302 G/A cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.34 -5.3 -0.43 5.04e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs2580764 0.566 rs2968793 chr2:55285024 C/T cg09592903 chr2:55203963 RTN4 0.26 5.97 0.47 2.27e-8 Mean platelet volume; TGCT cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.53 -5.0 -0.41 1.89e-6 Bipolar disorder; TGCT cis rs644799 1.000 rs3177463 chr11:95502128 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 11.08 0.71 2.9e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1862618 0.853 rs1423621 chr5:56101035 G/T cg24531977 chr5:56204891 C5orf35 -0.76 -7.75 -0.57 2.82e-12 Initial pursuit acceleration; TGCT trans rs208520 0.526 rs7776413 chr6:66783241 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.09 -16.9 -0.84 5.6e-34 Exhaled nitric oxide output; TGCT cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg08645402 chr16:4508243 NA 0.19 4.79 0.4 4.66e-6 Schizophrenia; TGCT cis rs6909430 0.539 rs11968196 chr6:98793832 A/G cg20000812 chr6:99276697 NA -0.51 -4.62 -0.38 9.54e-6 Quantitative traits; TGCT cis rs7647973 0.626 rs1078341 chr3:49685592 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs56104184 0.668 rs73063523 chr19:49408943 T/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg11494091 chr17:61959527 GH2 -0.6 -14.53 -0.79 1.48e-28 Prudent dietary pattern; TGCT cis rs4788570 0.697 rs9930015 chr16:71801092 C/G cg06353428 chr16:71660113 MARVELD3 1.51 11.99 0.73 1.81e-22 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs7659724 chr4:98944063 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9527 0.590 rs12775302 chr10:104911356 A/G cg15744005 chr10:104629667 AS3MT -0.41 -4.73 -0.39 6.06e-6 Arsenic metabolism; TGCT cis rs3812831 0.695 rs3118895 chr13:114931742 G/A cg06611532 chr13:114900021 NA 0.35 6.42 0.5 2.57e-9 Schizophrenia; TGCT trans rs1814175 0.781 rs11040681 chr11:49981654 G/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs3015497 0.789 rs10133849 chr14:51121700 A/G cg04730355 chr14:51134070 SAV1 -0.65 -6.29 -0.49 4.93e-9 Mean platelet volume; TGCT cis rs7615952 0.799 rs13315434 chr3:125641394 T/G cg05084668 chr3:125655381 ALG1L -0.7 -5.74 -0.46 6.93e-8 Blood pressure (smoking interaction); TGCT cis rs11098499 0.866 rs12374244 chr4:120281972 A/T cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs59107033 0.607 rs62262406 chr3:123122494 T/C cg04890266 chr3:123102914 ADCY5 -0.36 -5.43 -0.44 2.85e-7 Lymphocyte counts; TGCT cis rs2486012 1.000 rs2428960 chr1:44393146 A/G cg12908607 chr1:44402522 ARTN 0.73 5.67 0.45 9.51e-8 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.560 rs7912339 chr10:104373758 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9929218 0.954 rs4485355 chr16:68754730 C/T cg01251360 chr16:68772225 CDH1 0.29 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg22963979 chr7:1858916 MAD1L1 -0.44 -7.12 -0.54 7.88e-11 Bipolar disorder and schizophrenia; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg07205460 chr22:24236375 MIF 0.61 4.81 0.4 4.21e-6 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1153858 0.621 rs12913645 chr15:45555066 G/A cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.2 -0.42 8.07e-7 Homoarginine levels; TGCT cis rs651907 0.557 rs3864012 chr3:101397623 T/C cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.08 -0.54 9.37e-11 Colorectal cancer; TGCT cis rs12477438 0.520 rs11677247 chr2:99756358 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs7208859 0.673 rs11656845 chr17:29206164 G/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12220238 1.000 rs7076721 chr10:75996682 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.84 0.58 1.79e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2562456 0.754 rs55771551 chr19:21746380 C/T cg25650185 chr19:21324782 ZNF431 -0.66 -5.86 -0.47 3.92e-8 Pain; TGCT cis rs992157 0.560 rs12987130 chr2:219104990 T/C cg00012203 chr2:219082015 ARPC2 -0.81 -9.21 -0.64 1.03e-15 Colorectal cancer; TGCT cis rs694739 0.628 rs11606081 chr11:64137875 T/C cg02228329 chr11:64053129 BAD;GPR137 0.69 6.78 0.52 4.25e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg09904177 chr6:26538194 HMGN4 0.7 6.67 0.51 7.48e-10 Intelligence (multi-trait analysis); TGCT cis rs3935685 0.874 rs34906247 chr15:78004204 A/G cg25212270 chr15:78015279 NA 0.26 5.57 0.45 1.48e-7 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.735 rs858506 chr7:99820050 T/C cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs13256369 1.000 rs4840351 chr8:8573148 A/G cg06671706 chr8:8559999 CLDN23 0.34 4.44 0.37 1.99e-5 Obesity-related traits; TGCT cis rs5769765 0.773 rs9616383 chr22:50313014 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs17826219 0.561 rs562840 chr17:28949390 G/T cg19761014 chr17:28927070 LRRC37B2 0.53 4.63 0.38 9.04e-6 Body mass index; TGCT trans rs916888 0.821 rs199506 chr17:44859031 A/G cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7672749 0.643 rs7690494 chr4:88800539 A/G cg05816041 chr4:88786914 NA -0.52 -4.51 -0.38 1.48e-5 TB-LM or TBLH-BMD (pleiotropy); TGCT cis rs950776 0.642 rs61630816 chr15:78965866 T/C cg03762349 chr15:79060523 ADAMTS7 0.28 5.42 0.44 2.98e-7 Sudden cardiac arrest; TGCT cis rs7975161 1.000 rs7960443 chr12:104645363 G/A cg25273343 chr12:104657179 TXNRD1 -0.31 -4.86 -0.4 3.45e-6 Toenail selenium levels; TGCT cis rs12477438 0.765 rs13390672 chr2:99589829 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs1395 0.744 rs11126929 chr2:27472027 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.6 -7.79 -0.57 2.35e-12 Blood metabolite levels; TGCT cis rs9814567 1.000 rs13087875 chr3:134261123 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs74233809 0.901 rs17115100 chr10:104591393 G/T cg05855489 chr10:104503620 C10orf26 0.82 4.62 0.38 9.39e-6 Birth weight; TGCT cis rs10489202 0.608 rs7553238 chr1:168076768 G/A cg24449463 chr1:168025552 DCAF6 -0.49 -5.06 -0.41 1.49e-6 Schizophrenia; TGCT cis rs11931598 0.509 rs13140943 chr4:6977109 A/G cg02503808 chr4:7069936 GRPEL1 0.51 4.73 0.39 5.99e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs10114408 0.959 rs10761291 chr9:96640967 C/T cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7914558 0.966 rs4917997 chr10:104945213 A/G cg15744005 chr10:104629667 AS3MT -0.39 -4.73 -0.39 5.91e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs916888 0.773 rs199443 chr17:44819565 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.64 -5.6 -0.45 1.32e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs319204 1.000 rs167635 chr5:146260896 T/C cg25021259 chr5:146258546 PPP2R2B 0.38 4.72 0.39 6.14e-6 Schizophrenia; TGCT cis rs8017423 0.967 rs57793584 chr14:90714833 G/A cg04374321 chr14:90722782 PSMC1 0.74 7.74 0.57 2.98e-12 Mortality in heart failure; TGCT cis rs9911578 1.000 rs368186 chr17:56736659 A/G cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs13326165 0.760 rs11706108 chr3:52372366 T/C cg07884673 chr3:53033167 SFMBT1 0.4 4.86 0.4 3.45e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs597539 0.617 rs672853 chr11:68636362 G/A cg06028808 chr11:68637592 NA 0.52 6.73 0.52 5.58e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17826219 0.568 rs9898097 chr17:29072672 T/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs6089829 0.962 rs2872543 chr20:61665017 G/A cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs231513 1.000 rs231526 chr17:41951277 T/C cg26893861 chr17:41843967 DUSP3 -0.94 -6.51 -0.5 1.72e-9 Cognitive function; TGCT cis rs1371867 0.846 rs1692006 chr8:101252462 C/T cg06636551 chr8:101224915 SPAG1 0.48 6.57 0.51 1.28e-9 Atrioventricular conduction; TGCT trans rs12599106 0.679 rs34584967 chr16:34475725 T/G cg07332563 chr6:291687 DUSP22 -0.65 -6.72 -0.52 5.92e-10 Menopause (age at onset); TGCT cis rs10504229 0.679 rs16921687 chr8:58053514 T/C cg08280861 chr8:58055591 NA 0.35 4.88 0.4 3.2e-6 Developmental language disorder (linguistic errors); TGCT cis rs7829975 0.508 rs1594437 chr8:8825875 T/C cg15556689 chr8:8085844 FLJ10661 0.67 5.53 0.44 1.79e-7 Mood instability; TGCT cis rs9921338 0.961 rs56010295 chr16:11378907 G/A cg00044050 chr16:11439710 C16orf75 -0.87 -6.25 -0.49 5.97e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs739496 0.579 rs12321677 chr12:112339015 A/G cg10833066 chr12:111807467 FAM109A -0.38 -5.41 -0.44 3.08e-7 Platelet count; TGCT cis rs7584330 0.737 rs60187585 chr2:238365159 C/T cg14458575 chr2:238380390 NA 0.51 8.14 0.59 3.53e-13 Prostate cancer; TGCT cis rs10782582 0.609 rs2881785 chr1:76318096 T/C cg10523679 chr1:76189770 ACADM -0.61 -5.62 -0.45 1.22e-7 Daytime sleep phenotypes; TGCT cis rs9393777 0.528 rs34843552 chr6:27241915 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.55 -5.76 -0.46 6.38e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs10033138 chr4:98981922 A/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs313832 chr7:65550891 G/T cg20637647 chr7:64974828 NA 0.87 5.3 0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs8070740 0.898 rs4578712 chr17:5324431 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.77 0.39 5.1e-6 Menopause (age at onset); TGCT cis rs2485376 0.842 rs2145308 chr10:104150999 A/G cg26089160 chr10:104170217 PSD 0.51 5.07 0.41 1.41e-6 QT interval; TGCT cis rs7618915 0.501 rs1468638 chr3:52748058 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs3935685 0.874 rs4073356 chr15:78008430 C/T cg03457338 chr15:78040120 NA -0.23 -6.09 -0.48 1.34e-8 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.632 rs72807526 chr16:89775946 A/G cg26513180 chr16:89883248 FANCA -0.64 -5.6 -0.45 1.29e-7 Vitiligo; TGCT cis rs10992471 0.553 rs1923599 chr9:95092568 G/C cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -4.98 -0.41 2.06e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7208859 0.510 rs216402 chr17:28917126 A/T cg14008862 chr17:28927542 LRRC37B2 0.94 5.7 0.46 8.41e-8 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1580019 0.587 rs1597555 chr7:32546118 T/G cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.15 0.79 1.17e-27 Cognitive ability; TGCT cis rs7113874 0.523 rs7117945 chr11:8532458 C/T cg14521421 chr11:8862019 ST5 0.28 4.44 0.37 1.99e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs10838634 1.000 rs61898463 chr11:46873406 A/G cg18332754 chr11:46939436 LRP4 0.89 4.77 0.39 5.13e-6 Schizophrenia; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg12419862 chr22:24373484 LOC391322 -0.85 -9.35 -0.64 4.61e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2447097 0.935 rs2447095 chr17:2293420 A/G cg27406664 chr17:2294951 MNT 0.3 6.59 0.51 1.16e-9 Autism spectrum disorder; TGCT cis rs2204008 0.575 rs10444564 chr12:38043782 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.63 0.57 5.5e-12 Bladder cancer; TGCT cis rs1218582 0.772 rs1109815 chr1:154909268 A/G cg24250549 chr1:154909240 PMVK 0.62 6.12 0.48 1.14e-8 Prostate cancer; TGCT cis rs8177179 1.000 rs8177179 chr3:133463457 G/A cg24879335 chr3:133465180 TF 0.36 4.82 0.4 4.16e-6 Iron status biomarkers (transferrin levels); TGCT cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg13695892 chr22:41940480 POLR3H -0.93 -9.19 -0.64 1.15e-15 Vitiligo; TGCT cis rs1018836 0.923 rs10808615 chr8:91569704 A/T cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg07061783 chr6:25882402 NA -0.59 -5.78 -0.46 5.76e-8 Intelligence (multi-trait analysis); TGCT cis rs4595586 0.546 rs10876163 chr12:39244915 G/A cg26384229 chr12:38710491 ALG10B 0.65 5.29 0.43 5.43e-7 Morning vs. evening chronotype; TGCT cis rs651907 0.557 rs7651721 chr3:101393583 C/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colorectal cancer; TGCT cis rs10504229 0.636 rs115738451 chr8:58055133 A/T cg11062466 chr8:58055876 NA 0.43 4.64 0.38 8.85e-6 Developmental language disorder (linguistic errors); TGCT cis rs10782582 0.632 rs77099976 chr1:76240524 T/C cg03433033 chr1:76189801 ACADM -0.45 -4.6 -0.38 1.02e-5 Daytime sleep phenotypes; TGCT cis rs114540395 0.687 rs75269434 chr10:103473111 G/C cg03300883 chr10:102748874 C10orf2 0.42 4.69 0.39 7.16e-6 Schizophrenia; TGCT cis rs2721195 0.967 rs1480000 chr8:145702007 C/T cg15320075 chr8:145703422 NA -0.72 -7.61 -0.56 5.87e-12 Age at first birth; TGCT cis rs10927875 0.632 rs10927863 chr1:16165247 C/A cg21385522 chr1:16154831 NA -1.01 -18.25 -0.85 6.38e-37 Dilated cardiomyopathy; TGCT cis rs7772486 0.686 rs9386131 chr6:146121608 G/A cg23711669 chr6:146136114 FBXO30 0.86 9.53 0.65 1.74e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.61 -0.38 9.71e-6 Schizophrenia; TGCT cis rs7945705 1.000 rs7937298 chr11:8867509 G/C cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.96 0.41 2.3e-6 Hemoglobin concentration; TGCT cis rs13326165 0.760 rs3752819 chr3:52400740 G/C cg27565382 chr3:53032988 SFMBT1 0.36 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7809950 0.817 rs11535285 chr7:107143866 A/G cg23024343 chr7:107201750 COG5 -0.47 -6.89 -0.53 2.54e-10 Coronary artery disease; TGCT cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs7147624 0.608 rs4902413 chr14:66187091 T/C cg03016385 chr14:66212404 NA -0.5 -7.04 -0.53 1.13e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9902453 0.874 rs62070271 chr17:28268358 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.26 0.6 1.9e-13 Coffee consumption (cups per day); TGCT cis rs4665809 0.590 rs3806514 chr2:26466772 C/T cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs9914544 0.932 rs11870265 chr17:18820985 A/T cg26306683 chr17:18585705 ZNF286B 0.58 5.25 0.43 6.53e-7 Educational attainment (years of education); TGCT cis rs57590327 0.679 rs35259664 chr3:81586742 C/G cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs7017914 0.934 rs6998024 chr8:71660840 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs9788721 0.836 rs17483721 chr15:78733731 C/T cg18825076 chr15:78729989 IREB2 0.31 5.11 0.42 1.17e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs4478858 0.684 rs7515988 chr1:31731061 C/T cg07478791 chr1:31886160 SERINC2 0.52 5.05 0.41 1.53e-6 Alcohol dependence; TGCT trans rs7726839 0.561 rs72703050 chr5:582917 A/C cg25482853 chr8:67687455 SGK3 1.07 8.9 0.62 5.55e-15 Obesity-related traits; TGCT cis rs2072499 0.966 rs2842869 chr1:156160696 A/G cg06970220 chr1:156163860 SLC25A44 0.72 6.3 0.49 4.62e-9 Testicular germ cell tumor; TGCT cis rs9341808 0.644 rs76102095 chr6:80942026 G/C cg08355045 chr6:80787529 NA -0.28 -4.52 -0.38 1.45e-5 Sitting height ratio; TGCT cis rs9326248 0.539 rs7120565 chr11:117042949 T/C cg01368799 chr11:117014884 PAFAH1B2 0.57 5.26 0.43 6.17e-7 Blood protein levels; TGCT cis rs67385638 1.000 rs10837697 chr11:5281018 G/C cg12559170 chr11:5275217 HBG2 0.48 8.83 0.62 8.46e-15 Hemoglobin levels; TGCT cis rs13191362 0.507 rs2023015 chr6:163060528 A/T cg06582575 chr6:163149167 PACRG;PARK2 -0.6 -5.72 -0.46 7.61e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11250098 0.583 rs7001456 chr8:10804865 C/G cg16664915 chr8:10907788 XKR6 -0.29 -4.5 -0.37 1.52e-5 Morning vs. evening chronotype; TGCT cis rs858239 0.600 rs10256361 chr7:23123885 C/T cg05602783 chr7:23145260 KLHL7 -0.64 -5.36 -0.43 3.9e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10779751 0.960 rs4845860 chr1:11324193 A/G cg08854313 chr1:11322531 MTOR 0.96 9.03 0.63 2.76e-15 Body mass index; TGCT cis rs2204008 0.837 rs11183232 chr12:37941053 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.93 0.4 2.57e-6 Bladder cancer; TGCT cis rs1421811 0.509 rs7733428 chr5:32689850 G/A cg16267343 chr5:32710456 NPR3 0.74 6.6 0.51 1.08e-9 Blood pressure; TGCT cis rs1580019 0.523 rs13236410 chr7:32690663 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.59 4.88 0.4 3.18e-6 Cognitive ability; TGCT cis rs3771570 0.901 rs62190410 chr2:242410621 C/T cg21155796 chr2:242212141 HDLBP 0.93 6.69 0.52 6.74e-10 Prostate cancer; TGCT cis rs2046867 0.818 rs17010184 chr3:72870242 A/T cg25664220 chr3:72788482 NA 0.56 7.03 0.53 1.24e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7617773 0.963 rs12493256 chr3:48176747 C/T cg11946769 chr3:48343235 NME6 -0.57 -5.05 -0.41 1.57e-6 Coronary artery disease; TGCT cis rs2073300 1.000 rs6048825 chr20:23457671 T/C cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs6750047 0.573 rs162329 chr2:38318940 T/C cg07380506 chr2:38303506 CYP1B1 0.59 5.47 0.44 2.37e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs651907 0.557 rs34181125 chr3:101490278 A/G cg12386194 chr3:101231763 SENP7 0.48 4.7 0.39 6.71e-6 Colorectal cancer; TGCT cis rs981844 0.712 rs4434231 chr4:154746293 G/T cg14289246 chr4:154710475 SFRP2 -0.99 -9.24 -0.64 8.63e-16 Response to statins (LDL cholesterol change); TGCT cis rs8179 0.645 rs11771637 chr7:92260161 G/A cg15732164 chr7:92237376 CDK6 -0.29 -5.06 -0.41 1.46e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs425277 0.606 rs2459984 chr1:2086312 A/G cg24578937 chr1:2090814 PRKCZ 0.26 6.52 0.51 1.63e-9 Height; TGCT cis rs2439831 0.867 rs12324572 chr15:43636200 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT trans rs561341 1.000 rs483301 chr17:30293398 G/T cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs2688608 1.000 rs2688608 chr10:75658349 G/T cg23231163 chr10:75533350 FUT11 -0.26 -4.65 -0.39 8.32e-6 Inflammatory bowel disease; TGCT cis rs13401104 0.587 rs55801537 chr2:237145481 C/T cg19324714 chr2:237145437 ASB18 0.48 5.03 0.41 1.67e-6 Educational attainment; TGCT cis rs12210905 1.000 rs4636015 chr6:27097316 C/T cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs3020736 0.500 rs6002605 chr22:42494335 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2204008 0.777 rs11179774 chr12:38219559 A/C cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs13177718 0.908 rs7713158 chr5:108179300 G/A cg20423064 chr5:108166851 FER -0.58 -5.53 -0.45 1.77e-7 Height; TGCT cis rs9393777 0.920 rs55834529 chr6:27072542 A/G cg16898833 chr6:26189333 HIST1H4D 1.29 5.83 0.46 4.6e-8 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.901 rs1540276 chr6:26028819 T/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.59 -5.97 -0.47 2.31e-8 Intelligence (multi-trait analysis); TGCT cis rs11585357 0.895 rs877552 chr1:17631236 C/T cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs6866344 0.697 rs62392832 chr5:178134395 T/C cg03877680 chr5:178157825 ZNF354A 0.75 6.1 0.48 1.25e-8 Neutrophil percentage of white cells; TGCT cis rs597539 0.617 rs686348 chr11:68636996 A/G cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs752590 0.887 rs7603621 chr2:113953984 G/A cg27425262 chr2:113953981 PSD4;LOC440839 0.4 4.65 0.39 8.35e-6 Mucinous ovarian carcinoma; TGCT cis rs12142240 0.698 rs67142569 chr1:46828460 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs8072100 0.790 rs11656856 chr17:45714671 C/T cg08085267 chr17:45401833 C17orf57 0.46 5.05 0.41 1.55e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs35883536 0.647 rs10875313 chr1:101043057 T/C cg10298815 chr1:101004474 GPR88 -0.25 -4.73 -0.39 6.03e-6 Monocyte count; TGCT cis rs7714584 0.793 rs7709721 chr5:150246858 A/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs4595586 0.545 rs4623945 chr12:39364572 A/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7267979 1.000 rs1888999 chr20:25291848 C/T cg14121845 chr20:25566513 NINL 0.5 5.42 0.44 2.98e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs739401 0.572 rs410820 chr11:3080102 G/A cg05729581 chr11:3078854 CARS -0.57 -5.21 -0.42 7.77e-7 Longevity; TGCT cis rs7587476 0.601 rs17489231 chr2:215673739 T/G cg04004882 chr2:215674386 BARD1 -0.64 -4.99 -0.41 1.98e-6 Neuroblastoma; TGCT trans rs17685 0.753 rs11972240 chr7:75694079 A/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1218582 0.772 rs10796934 chr1:154849479 C/G cg03351412 chr1:154909251 PMVK 0.52 4.7 0.39 6.89e-6 Prostate cancer; TGCT cis rs10992471 0.528 rs10429459 chr9:95258119 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.48 4.44 0.37 1.95e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs67072384 1.000 rs66628852 chr11:72454260 C/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT trans rs1415174 0.958 rs11161995 chr1:87847764 A/G cg23065576 chr20:25207247 ENTPD6 -0.27 -6.8 -0.52 3.88e-10 Breast cancer; TGCT cis rs11677203 0.958 rs6728483 chr2:12567278 G/A cg00419568 chr2:11919532 LPIN1 -0.2 -4.47 -0.37 1.72e-5 Electroencephalogram traits; TGCT cis rs13256369 0.901 rs4841015 chr8:8567140 C/G cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6879260 1.000 rs7706951 chr5:179733407 C/T cg23221052 chr5:179740743 GFPT2 -0.36 -5.75 -0.46 6.7e-8 Height; TGCT cis rs8077889 1.000 rs17675122 chr17:41886190 A/G cg26893861 chr17:41843967 DUSP3 1.1 12.5 0.75 1.08e-23 Triglycerides; TGCT cis rs9926296 0.632 rs4785717 chr16:89801133 A/G cg04287289 chr16:89883240 FANCA 0.67 6.64 0.51 8.68e-10 Vitiligo; TGCT cis rs6920965 0.507 rs9385388 chr6:126215296 C/T cg05901451 chr6:126070800 HEY2 -0.64 -6.47 -0.5 2.02e-9 High light scatter reticulocyte count; TGCT cis rs6750047 0.605 rs59501228 chr2:38261972 A/C cg07380506 chr2:38303506 CYP1B1 -0.58 -5.2 -0.42 8.09e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs9914988 0.943 rs4795465 chr17:27151498 A/G cg20469991 chr17:27169893 C17orf63 0.72 5.09 0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1215050 0.740 rs2695464 chr4:98980929 T/C cg05340658 chr4:99064831 C4orf37 -0.43 -5.27 -0.43 5.8e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2439831 1.000 rs690263 chr15:43704465 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.22 0.49 6.97e-9 Lung cancer in ever smokers; TGCT cis rs1964356 0.967 rs2953802 chr8:8851881 G/A cg06636001 chr8:8085503 FLJ10661 0.71 6.21 0.49 7.22e-9 Mean corpuscular volume; TGCT cis rs2013441 1.000 rs2107566 chr17:20103252 C/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.62 -0.38 9.59e-6 Obesity-related traits; TGCT cis rs4689388 0.926 rs4458523 chr4:6289986 G/T cg00701064 chr4:6280414 WFS1 -0.4 -5.11 -0.42 1.2e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs66573146 0.831 rs73088564 chr4:6984553 G/C cg07817883 chr1:32538562 TMEM39B 1.42 7.53 0.56 8.92e-12 Granulocyte percentage of myeloid white cells; TGCT cis rs11711311 0.712 rs3773683 chr3:113341007 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.69 -5.81 -0.46 5.03e-8 IgG glycosylation; TGCT cis rs751728 1.000 rs9394166 chr6:33751122 G/C cg00334056 chr6:33755658 LEMD2 -0.25 -4.58 -0.38 1.11e-5 Crohn's disease; TGCT cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9790314 1.000 rs4350933 chr3:160955879 G/T cg03342759 chr3:160939853 NMD3 -0.43 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs459571 0.959 rs2520099 chr9:136918139 T/C cg13789015 chr9:136890014 NCRNA00094 0.38 6.66 0.51 7.97e-10 Platelet distribution width; TGCT trans rs1005277 0.579 rs2505248 chr10:38459097 A/G cg17830980 chr10:43048298 ZNF37B -0.88 -11.22 -0.71 1.37e-20 Extrinsic epigenetic age acceleration; TGCT cis rs2836950 0.565 rs2836943 chr21:40592611 C/T cg11890956 chr21:40555474 PSMG1 -0.7 -6.87 -0.52 2.79e-10 Menarche (age at onset); TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg00024416 chr22:24240387 NA -0.25 -4.76 -0.39 5.27e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs62103177 0.714 rs28691615 chr18:77612254 C/T cg12964065 chr18:77638022 KCNG2 0.33 4.63 0.38 9.08e-6 Opioid sensitivity; TGCT cis rs1062177 1.000 rs2915887 chr5:151205504 C/T cg12924095 chr5:151150029 G3BP1 0.36 5.18 0.42 8.79e-7 Preschool internalizing problems; TGCT cis rs3806843 0.576 rs246036 chr5:140331886 T/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9611565 0.649 rs202666 chr22:41814719 T/C cg13695892 chr22:41940480 POLR3H 0.91 9.11 0.63 1.79e-15 Vitiligo; TGCT cis rs13394619 1.000 rs4669752 chr2:11727988 G/C cg07314298 chr2:11723111 GREB1 -0.29 -5.26 -0.43 6.09e-7 Endometriosis; TGCT cis rs1008375 1.000 rs17507481 chr4:17620066 A/G cg10189774 chr4:17578691 LAP3 0.67 5.84 0.46 4.33e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg07092213 chr7:1199455 ZFAND2A -0.43 -4.62 -0.38 9.36e-6 Longevity;Endometriosis; TGCT cis rs826838 1.000 rs11609286 chr12:38875511 A/G cg13010199 chr12:38710504 ALG10B -0.82 -6.85 -0.52 3e-10 Heart rate; TGCT cis rs8037137 0.571 rs3743445 chr15:91561182 C/T cg22570213 chr15:91497863 RCCD1 0.52 4.86 0.4 3.41e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs17152411 0.895 rs7094381 chr10:126585848 G/A cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs6840360 0.593 rs28602726 chr4:152499788 T/C cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs13102973 0.645 rs7692242 chr4:135886041 A/G cg14419869 chr4:135874104 NA 0.26 4.6 0.38 1.03e-5 Subjective well-being; TGCT cis rs7236492 0.572 rs7244366 chr18:77179746 C/T cg15644404 chr18:77186268 NFATC1 -0.43 -4.5 -0.37 1.57e-5 Inflammatory bowel disease;Crohn's disease; TGCT trans rs9467711 1.000 rs6939799 chr6:26328366 G/A cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs7119 0.717 rs12917314 chr15:77818285 T/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.61 -0.38 9.81e-6 Type 2 diabetes; TGCT cis rs4631830 0.900 rs7914347 chr10:51537431 C/T cg10326726 chr10:51549505 MSMB -0.25 -5.27 -0.43 5.77e-7 Prostate-specific antigen levels; TGCT cis rs9814567 1.000 rs9827987 chr3:134272621 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.89 -0.66 2.32e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7552404 0.921 rs10873685 chr1:76218818 A/C cg03433033 chr1:76189801 ACADM 0.84 9.67 0.66 8.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9549367 0.713 rs576463 chr13:113846614 C/T cg18105134 chr13:113819100 PROZ 0.46 8.58 0.61 3.25e-14 Platelet distribution width; TGCT cis rs13256369 0.802 rs11249887 chr8:8562184 T/C cg17143192 chr8:8559678 CLDN23 0.54 5.06 0.41 1.47e-6 Obesity-related traits; TGCT cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.55 -6.35 -0.5 3.74e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs13242816 1.000 rs55833477 chr7:116110375 C/G cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs2832191 1.000 rs2832184 chr21:30483265 C/T cg08807101 chr21:30365312 RNF160 -0.49 -4.48 -0.37 1.65e-5 Dental caries; TGCT trans rs35365539 1 rs35365539 chr3:49794347 A/AC cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Blood protein levels; TGCT cis rs9486719 1.000 rs9373978 chr6:97056255 T/C cg18709589 chr6:96969512 KIAA0776 -0.77 -5.47 -0.44 2.38e-7 Migraine;Coronary artery disease; TGCT cis rs11969893 0.737 rs9498439 chr6:101404768 A/T cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs2046867 0.954 rs1490507 chr3:72781356 G/A cg25664220 chr3:72788482 NA 0.53 6.61 0.51 1e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs346785 0.692 rs6501880 chr17:74289705 A/G cg09812376 chr17:74270190 QRICH2 -0.36 -5.33 -0.43 4.43e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs7829975 0.539 rs883647 chr8:8569724 G/A cg06636001 chr8:8085503 FLJ10661 -0.6 -5.08 -0.42 1.33e-6 Mood instability; TGCT cis rs7267979 1.000 rs2258879 chr20:25279213 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs1124253 chr4:98949682 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs114540395 0.925 rs17696674 chr10:103415063 A/T cg03300883 chr10:102748874 C10orf2 0.43 4.5 0.37 1.52e-5 Schizophrenia; TGCT cis rs2075165 0.836 rs7512751 chr1:156234439 T/G cg16558208 chr1:156270281 VHLL 0.26 4.46 0.37 1.8e-5 Tonsillectomy; TGCT cis rs7208859 0.673 rs3764421 chr17:29167653 A/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7020830 0.931 rs13297576 chr9:37142189 A/C cg14294708 chr9:37120828 ZCCHC7 1.29 19.18 0.86 6.46e-39 Schizophrenia; TGCT trans rs8073060 0.586 rs4796098 chr17:33913436 T/C cg19694781 chr19:47549865 TMEM160 0.6 13.04 0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9811920 0.609 rs793460 chr3:99615733 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.82 -0.52 3.63e-10 Axial length; TGCT cis rs6089829 0.747 rs57767914 chr20:61659108 C/G cg03213289 chr20:61660250 NA -0.51 -5.59 -0.45 1.38e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs4409675 0.556 rs2064710 chr1:28231154 G/A cg23691781 chr1:28212827 C1orf38 0.25 5.38 0.43 3.59e-7 Corneal astigmatism; TGCT cis rs2361718 0.933 rs8077849 chr17:78104137 C/T cg09238746 chr17:78121135 EIF4A3 -0.55 -4.68 -0.39 7.5e-6 Yeast infection; TGCT cis rs11971779 0.838 rs58074268 chr7:139108925 C/T cg07862535 chr7:139043722 LUC7L2 0.76 5.49 0.44 2.15e-7 Diisocyanate-induced asthma; TGCT cis rs986417 1.000 rs1272688 chr14:60920718 T/C cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs17331151 0.505 rs79993196 chr3:52697566 T/C cg15956490 chr3:53032818 SFMBT1 0.7 5.71 0.46 7.8e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs12477438 0.520 rs13010904 chr2:99754289 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 12.89 0.76 1.24e-24 Chronic sinus infection; TGCT cis rs921968 0.541 rs4674310 chr2:219318078 T/C cg02176678 chr2:219576539 TTLL4 -0.47 -6.78 -0.52 4.34e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7818688 0.654 rs11783262 chr8:95979816 A/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs3936340 1.000 rs3936340 chr19:48527582 A/G cg03707168 chr19:49379127 PPP1R15A -0.6 -4.56 -0.38 1.22e-5 Intelligence; TGCT trans rs7618501 0.540 rs11130241 chr3:50131459 A/T cg21659725 chr3:3221576 CRBN -0.74 -8.78 -0.62 1.08e-14 Intelligence (multi-trait analysis); TGCT cis rs1215050 0.818 rs1214917 chr4:99080029 G/T cg05340658 chr4:99064831 C4orf37 0.41 4.82 0.4 4.15e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9910055 0.762 rs11080007 chr17:42265442 A/G cg19774624 chr17:42201019 HDAC5 0.72 7.69 0.57 3.88e-12 Total body bone mineral density; TGCT cis rs35146811 0.735 rs1043915 chr7:99799845 T/A cg04778012 chr7:99775508 STAG3;GPC2 0.34 4.61 0.38 9.84e-6 Coronary artery disease; TGCT cis rs916888 0.773 rs199448 chr17:44809001 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.79 5.65 0.45 1.06e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7666738 0.830 rs10005173 chr4:98816062 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.45 0.56 1.42e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7439150 0.954 rs72681204 chr4:155476145 C/A cg22130008 chr4:155548532 NA -0.43 -5.43 -0.44 2.87e-7 Fibrinogen levels; TGCT cis rs7666738 0.830 rs17027058 chr4:98864671 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.59 0.56 6.56e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4273100 1.000 rs16960158 chr17:19163052 A/C cg01534423 chr17:18965556 NA 0.91 5.95 0.47 2.6e-8 Schizophrenia; TGCT cis rs1887596 0.624 rs4769504 chr13:27130516 A/G cg01312412 chr13:27282625 NA 0.27 4.74 0.39 5.68e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs9467773 0.967 rs6932865 chr6:26540166 C/A cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs4455778 0.580 rs4291221 chr7:49114465 C/T cg26309511 chr7:48887640 NA -0.5 -6.47 -0.5 2.02e-9 Lung cancer in never smokers; TGCT cis rs1348850 0.831 rs7606235 chr2:178401288 T/C cg22681709 chr2:178499509 PDE11A -0.36 -4.59 -0.38 1.06e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2455799 0.552 rs1472697 chr3:15750268 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.69 -0.39 6.96e-6 Mean platelet volume; TGCT cis rs1865760 0.516 rs9358903 chr6:26061949 A/C cg16482183 chr6:26056742 HIST1H1C 0.57 4.99 0.41 1.99e-6 Height; TGCT cis rs7017914 0.902 rs6472562 chr8:71969878 A/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.28 -0.43 5.57e-7 Bone mineral density; TGCT cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg09436375 chr6:42928200 GNMT -0.4 -5.19 -0.42 8.31e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7582180 0.638 rs6734316 chr2:100976210 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs4713118 0.513 rs149972 chr6:27983227 C/T cg10876282 chr6:28092338 ZSCAN16 0.49 4.49 0.37 1.6e-5 Parkinson's disease; TGCT cis rs2836974 0.584 rs7276774 chr21:40628725 T/G cg06238570 chr21:40685208 BRWD1 -0.8 -9.0 -0.63 3.3e-15 Cognitive function; TGCT cis rs2842992 0.789 rs7758895 chr6:160193465 T/C cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs57920188 0.535 rs77116992 chr1:4095498 T/A cg20703997 chr1:4087676 NA 0.48 5.62 0.45 1.19e-7 Interleukin-17 levels; TGCT cis rs2692947 0.673 rs1168965 chr2:96787899 C/G cg05933789 chr2:97190408 NA -0.16 -4.61 -0.38 9.67e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs34546498 1 rs34546498 chr6:26961280 C/T cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Breast cancer; TGCT cis rs7027203 0.717 rs7869328 chr9:96588782 A/G cg14598338 chr9:96623480 NA -0.62 -9.51 -0.65 1.96e-16 DNA methylation (variation); TGCT trans rs877282 0.853 rs11595510 chr10:756757 C/G cg22713356 chr15:30763199 NA 1.01 8.45 0.6 6.58e-14 Uric acid levels; TGCT cis rs4074961 0.565 rs10908362 chr1:38061706 G/C cg17933807 chr1:38061675 GNL2 1.09 16.99 0.84 3.64e-34 Axial length; TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg21672276 chr3:44754072 ZNF502 -0.43 -4.82 -0.4 4.06e-6 Depressive symptoms; TGCT cis rs9291683 0.546 rs13129453 chr4:10044784 T/C cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Bone mineral density; TGCT cis rs10782582 0.609 rs12138898 chr1:76375183 G/T cg10523679 chr1:76189770 ACADM -0.58 -5.24 -0.43 6.74e-7 Daytime sleep phenotypes; TGCT cis rs1008375 1.000 rs11947857 chr4:17691047 T/C cg16339924 chr4:17578868 LAP3 -0.58 -4.58 -0.38 1.11e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4919669 0.668 rs4146428 chr10:104401721 G/A cg05855489 chr10:104503620 C10orf26 0.76 4.44 0.37 1.98e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs4478858 0.735 rs7523438 chr1:31788313 C/T cg07478791 chr1:31886160 SERINC2 0.47 4.6 0.38 1.03e-5 Alcohol dependence; TGCT cis rs10256972 0.732 rs12701856 chr7:1107707 C/T cg18765753 chr7:1198926 ZFAND2A -0.41 -4.55 -0.38 1.26e-5 Longevity;Endometriosis; TGCT cis rs2932538 0.885 rs6691025 chr1:113177070 G/T cg22162597 chr1:113214053 CAPZA1 -0.27 -5.88 -0.47 3.49e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7617773 0.501 rs12185901 chr3:48382919 G/T cg11946769 chr3:48343235 NME6 0.55 4.6 0.38 1.02e-5 Coronary artery disease; TGCT cis rs6582630 0.555 rs11610015 chr12:38508856 A/G cg26384229 chr12:38710491 ALG10B 0.83 7.75 0.57 2.83e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs9894429 0.789 rs9747336 chr17:79584189 C/T cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT cis rs2204008 0.537 rs11170128 chr12:38006632 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.2 0.54 4.98e-11 Bladder cancer; TGCT cis rs9399135 1.000 rs9399135 chr6:135368314 G/A cg24558204 chr6:135376177 HBS1L 0.46 4.6 0.38 1.05e-5 Red blood cell count; TGCT cis rs11122272 0.735 rs2808603 chr1:231537738 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.24 -0.49 6.42e-9 Hemoglobin concentration; TGCT cis rs4409675 0.597 rs1000431 chr1:28225114 C/T cg23691781 chr1:28212827 C1orf38 0.25 5.26 0.43 6.19e-7 Corneal astigmatism; TGCT cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg19774624 chr17:42201019 HDAC5 -0.86 -9.25 -0.64 8.4e-16 Total body bone mineral density; TGCT cis rs3892630 0.612 rs10413282 chr19:33182751 A/G cg22980127 chr19:33182716 NUDT19 0.8 6.61 0.51 1.04e-9 Red blood cell traits; TGCT cis rs3774830 0.846 rs17367340 chr4:5457009 T/G cg26943120 chr4:5472116 STK32B 0.26 6.22 0.49 6.95e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs1814175 0.653 rs10839480 chr11:50034556 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs6500602 0.893 rs934888 chr16:4462832 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 5.31 0.43 4.92e-7 Schizophrenia; TGCT cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.76 -0.46 6.11e-8 Coronary artery disease; TGCT cis rs6061231 0.624 rs8668 chr20:60964064 C/T cg24112000 chr20:60950667 NA 0.37 4.93 0.41 2.53e-6 Colorectal cancer; TGCT cis rs9399137 0.507 rs11754021 chr6:135308375 A/G cg24558204 chr6:135376177 HBS1L 0.46 4.65 0.39 8.46e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs10883723 0.773 rs11191313 chr10:104278618 C/T cg05855489 chr10:104503620 C10orf26 -0.6 -5.18 -0.42 8.85e-7 Allergic disease (asthma, hay fever or eczema); TGCT cis rs79349575 0.687 rs12602179 chr17:47010034 G/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs854765 0.583 rs4534911 chr17:17852330 A/G cg09796270 chr17:17721594 SREBF1 0.27 5.42 0.44 2.99e-7 Total body bone mineral density; TGCT cis rs10170846 0.861 rs4674677 chr2:223529658 G/A cg25565276 chr2:223520875 FARSB 0.55 4.58 0.38 1.1e-5 Schizophrenia (inflammation and infection response interaction); TGCT cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg20607798 chr8:58055168 NA -0.49 -4.51 -0.38 1.46e-5 Developmental language disorder (linguistic errors); TGCT cis rs2544527 0.586 rs2544534 chr2:15906466 T/C cg26669897 chr2:15909070 NA 0.42 5.07 0.41 1.39e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs73110464 0.562 rs2363634 chr12:53354683 A/G cg05393297 chr12:53359155 NA -0.79 -8.34 -0.6 1.18e-13 Cancer (pleiotropy); TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg27535305 chr1:53392650 SCP2 -0.27 -5.38 -0.44 3.57e-7 Monocyte count; TGCT cis rs1878931 0.520 rs12447807 chr16:3413896 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.96 11.15 0.71 1.96e-20 Body mass index (adult); TGCT cis rs7647973 0.961 rs11130186 chr3:49275828 A/G cg07636037 chr3:49044803 WDR6 0.67 5.41 0.44 3.15e-7 Menarche (age at onset); TGCT cis rs9303401 0.659 rs34468504 chr17:56648277 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs3096299 0.658 rs3934737 chr16:89560209 G/A cg08392591 chr16:89556376 ANKRD11 0.56 5.2 0.42 8.06e-7 Multiple myeloma (IgH translocation); TGCT cis rs4851254 0.920 rs11689956 chr2:100795329 T/C cg23118464 chr2:100721844 AFF3 0.58 4.46 0.37 1.84e-5 Intelligence (multi-trait analysis); TGCT cis rs1799949 1.000 rs12936816 chr17:41301709 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs59107033 0.607 rs9840967 chr3:123127106 A/G cg04890266 chr3:123102914 ADCY5 0.39 5.94 0.47 2.67e-8 Lymphocyte counts; TGCT cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg06634786 chr22:41940651 POLR3H -0.86 -8.01 -0.58 7.16e-13 Vitiligo; TGCT cis rs155076 0.938 rs485361 chr13:21845826 G/T cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs7829975 0.593 rs2921051 chr8:8320104 C/A cg06636001 chr8:8085503 FLJ10661 0.79 7.89 0.58 1.39e-12 Mood instability; TGCT cis rs9611565 0.765 rs132906 chr22:41799767 G/C cg17554472 chr22:41940697 POLR3H 0.41 4.55 0.38 1.24e-5 Vitiligo; TGCT cis rs3806843 0.548 rs246056 chr5:140325600 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.11e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs1401999 0.510 rs17817736 chr3:183720313 A/T cg01324343 chr3:183735012 ABCC5 -0.48 -5.1 -0.42 1.21e-6 Anterior chamber depth; TGCT cis rs66573146 0.831 rs56300156 chr4:6990813 G/C cg05069807 chr4:6945702 TBC1D14 0.31 4.85 0.4 3.63e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1008375 0.931 rs10019482 chr4:17578079 G/A cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs2727020 0.658 rs4980442 chr11:49445016 G/T cg03929089 chr4:120376271 NA -0.74 -8.56 -0.61 3.56e-14 Coronary artery disease; TGCT cis rs514406 0.929 rs555741 chr1:53318851 T/G cg08736216 chr1:53307985 ZYG11A -0.3 -6.06 -0.48 1.48e-8 Monocyte count; TGCT cis rs1577917 0.958 rs12199832 chr6:86652748 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs12780845 0.540 rs3824632 chr10:17230999 A/G cg01003015 chr10:17271136 VIM 0.49 4.53 0.38 1.35e-5 Homocysteine levels; TGCT cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg10802521 chr3:52805072 NEK4 0.77 9.32 0.64 5.7e-16 Bipolar disorder; TGCT cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg02458000 chr6:26745757 NA -0.54 -5.32 -0.43 4.69e-7 Intelligence (multi-trait analysis); TGCT cis rs4654899 0.758 rs12078457 chr1:21397071 C/T cg01072550 chr1:21505969 NA -0.57 -9.35 -0.64 4.68e-16 Superior frontal gyrus grey matter volume; TGCT cis rs56873913 0.904 rs3760708 chr19:50084596 G/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.65 5.32 0.43 4.59e-7 Schizophrenia; TGCT cis rs734999 0.611 rs10797431 chr1:2501222 G/T cg18854424 chr1:2615690 NA 0.46 5.34 0.43 4.29e-7 Ulcerative colitis; TGCT cis rs4803468 1.000 rs2304242 chr19:41944616 G/T cg09537434 chr19:41945824 ATP5SL 0.91 10.05 0.67 9.48e-18 Height; TGCT cis rs28735056 0.904 rs11665111 chr18:77622996 T/C cg20368463 chr18:77673604 PQLC1 0.39 4.76 0.39 5.21e-6 Schizophrenia; TGCT cis rs12286929 0.576 rs2275997 chr11:115100186 A/G cg04017736 chr11:115827165 NA -0.22 -5.8 -0.46 5.14e-8 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1568889 1.000 rs7945367 chr11:28166272 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.68 0.61 1.88e-14 Bipolar disorder; TGCT cis rs611744 0.573 rs1457210 chr8:109261562 A/G cg21045802 chr8:109455806 TTC35 -0.63 -6.57 -0.51 1.23e-9 Dupuytren's disease; TGCT cis rs10254284 0.959 rs11771411 chr7:28149761 T/C cg23620719 chr7:28220237 JAZF1 -0.54 -4.81 -0.4 4.38e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs262150 0.672 rs2730230 chr7:158788529 A/G cg19418458 chr7:158789849 NA -0.43 -4.58 -0.38 1.13e-5 Facial morphology (factor 20); TGCT cis rs4455778 0.538 rs6977073 chr7:49115340 C/T cg26309511 chr7:48887640 NA 0.5 6.55 0.51 1.4e-9 Lung cancer in never smokers; TGCT trans rs1005277 0.579 rs1985707 chr10:38434098 C/T cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.81e-21 Extrinsic epigenetic age acceleration; TGCT cis rs10851411 0.908 rs2617236 chr15:42815733 A/T cg23803468 chr15:43513504 EPB42 0.23 4.46 0.37 1.82e-5 Glucose homeostasis traits; TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg11494091 chr17:61959527 GH2 0.61 14.35 0.79 4.1e-28 Prudent dietary pattern; TGCT cis rs1843834 0.858 rs4674933 chr2:225514923 C/T cg22455342 chr2:225449267 CUL3 0.74 7.46 0.56 1.29e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs12911832 0.701 rs452698 chr15:59105571 A/G cg05156742 chr15:59063176 FAM63B 0.56 5.25 0.43 6.3e-7 Schizophrenia; TGCT cis rs6840360 0.615 rs6831810 chr4:152461995 A/G cg17479576 chr4:152424074 FAM160A1 -0.71 -7.74 -0.57 2.95e-12 Intelligence (multi-trait analysis); TGCT cis rs2120019 1.000 rs12903201 chr15:75370776 A/C cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT cis rs7027203 0.828 rs4744287 chr9:96585567 A/G cg14598338 chr9:96623480 NA 0.61 9.88 0.66 2.5e-17 DNA methylation (variation); TGCT cis rs7824557 0.767 rs6985146 chr8:11170721 A/C cg21775007 chr8:11205619 TDH 0.48 4.81 0.4 4.27e-6 Retinal vascular caliber; TGCT cis rs921968 0.541 rs532425 chr2:219434194 A/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs11098499 0.909 rs9994810 chr4:120381590 A/G cg09307838 chr4:120376055 NA 0.71 6.98 0.53 1.57e-10 Corneal astigmatism; TGCT cis rs11175194 0.546 rs73122698 chr12:64210942 C/T cg17737263 chr12:64537067 SRGAP1 0.37 4.81 0.4 4.26e-6 Epithelial ovarian cancer; TGCT cis rs539096 0.501 rs713191 chr1:44314553 A/G cg12908607 chr1:44402522 ARTN -0.64 -7.74 -0.57 3e-12 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg00149659 chr3:10157352 C3orf10 0.92 5.82 0.46 4.71e-8 Alzheimer's disease; TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg08859206 chr1:53392774 SCP2 -0.46 -7.42 -0.55 1.64e-11 Monocyte count; TGCT cis rs2708977 1.000 rs34029026 chr2:97250042 T/C cg01950434 chr2:97203154 ARID5A 0.57 4.9 0.4 2.9e-6 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs6840360 1.000 rs907237 chr4:152601146 T/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.59 -0.45 1.37e-7 Intelligence (multi-trait analysis); TGCT cis rs797680 0.856 rs12044657 chr1:93639596 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.04 -0.41 1.59e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11971779 0.680 rs7808740 chr7:139028955 G/T cg07862535 chr7:139043722 LUC7L2 0.56 4.46 0.37 1.82e-5 Diisocyanate-induced asthma; TGCT cis rs6867032 1.000 rs4246753 chr5:2014721 G/A cg26168224 chr5:2018326 NA 0.43 7.96 0.58 9.45e-13 Gut microbiome composition (winter); TGCT cis rs3849570 0.695 rs6804587 chr3:81873423 T/C cg07356753 chr3:81810745 GBE1 -0.6 -5.31 -0.43 4.92e-7 Waist circumference;Body mass index; TGCT cis rs447921 0.861 rs67873924 chr17:74429992 C/G cg09812376 chr17:74270190 QRICH2 -0.48 -4.71 -0.39 6.4e-6 Mitochondrial DNA levels; TGCT cis rs79149102 0.579 rs6495140 chr15:75306041 T/C cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs72781680 0.898 rs12623079 chr2:24103749 G/A cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs12971120 1.000 rs2278161 chr18:72176083 T/C cg26446133 chr18:72167187 CNDP2 -0.33 -6.03 -0.48 1.74e-8 Refractive error; TGCT cis rs10992471 0.598 rs331380 chr9:95256519 C/T cg13798575 chr9:95087839 CENPP;NOL8 0.63 6.25 0.49 5.98e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4689388 0.890 rs1801206 chr4:6302707 C/T cg00701064 chr4:6280414 WFS1 0.43 5.66 0.45 9.73e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs727563 0.580 rs202626 chr22:41847190 C/A cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6545883 0.894 rs35292974 chr2:61522047 T/C cg15711740 chr2:61764176 XPO1 0.54 4.59 0.38 1.09e-5 Tuberculosis; TGCT cis rs8017423 0.967 rs7160032 chr14:90708472 A/G cg04374321 chr14:90722782 PSMC1 0.77 8.04 0.59 6.19e-13 Mortality in heart failure; TGCT cis rs644799 0.965 rs573758 chr11:95539591 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9796 0.870 rs28581803 chr15:41326513 G/A cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.32 -0.43 4.78e-7 Menopause (age at onset); TGCT cis rs1577917 0.739 rs9344532 chr6:86234070 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 5.38 0.43 3.61e-7 Response to antipsychotic treatment; TGCT cis rs6952808 0.510 rs13227554 chr7:2048220 G/C cg04267008 chr7:1944627 MAD1L1 0.36 4.59 0.38 1.05e-5 Bipolar disorder and schizophrenia; TGCT cis rs6684514 1.000 rs7522948 chr1:156275308 C/T cg16558208 chr1:156270281 VHLL 0.48 10.26 0.68 2.98e-18 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1801251 0.896 rs79793315 chr2:233690864 C/T cg08000102 chr2:233561755 GIGYF2 -0.59 -6.22 -0.49 6.86e-9 Coronary artery disease; TGCT cis rs796364 0.616 rs2140486 chr2:200690102 C/T cg17644776 chr2:200775616 C2orf69 0.34 4.84 0.4 3.76e-6 Schizophrenia; TGCT cis rs2549003 0.870 rs61175929 chr5:131821548 C/G cg02551604 chr5:131831745 NA -0.88 -11.45 -0.72 3.69e-21 Asthma (sex interaction); TGCT cis rs12497850 0.931 rs7430501 chr3:48890119 C/T cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs4319547 0.656 rs6488951 chr12:122873928 A/G cg05707623 chr12:122985044 ZCCHC8 -0.62 -4.87 -0.4 3.32e-6 Body mass index; TGCT cis rs9311474 0.629 rs4282054 chr3:52566065 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.53 5.07 0.41 1.42e-6 Electroencephalogram traits; TGCT cis rs4660261 0.526 rs803680 chr1:44364370 G/C cg13606994 chr1:44402422 ARTN -0.42 -4.56 -0.38 1.21e-5 Intelligence (multi-trait analysis); TGCT cis rs7959452 0.684 rs11177615 chr12:69754189 G/A cg20891283 chr12:69753455 YEATS4 0.83 8.52 0.61 4.61e-14 Blood protein levels; TGCT cis rs9303542 0.625 rs62065846 chr17:46592858 G/A cg25032089 chr17:46643351 HOXB3 0.57 5.74 0.46 6.78e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs367943 1.000 rs168365 chr5:112817984 G/A cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs9952991 0.883 rs2542147 chr18:12775851 G/T cg24737193 chr18:12778029 NA 0.53 5.93 0.47 2.8e-8 Inflammatory skin disease; TGCT cis rs7937682 0.562 rs955744 chr11:111374334 C/T cg09085632 chr11:111637200 PPP2R1B 0.7 6.48 0.5 1.94e-9 Primary sclerosing cholangitis; TGCT cis rs2562456 0.833 rs2968076 chr19:21637101 C/T cg01304269 chr19:21688519 ZNF429 -0.61 -4.89 -0.4 3.06e-6 Pain; TGCT cis rs7312933 0.558 rs11181466 chr12:42765181 A/T cg19980929 chr12:42632907 YAF2 0.43 6.03 0.48 1.79e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9291683 0.527 rs11727087 chr4:10096020 A/G cg00071950 chr4:10020882 SLC2A9 0.53 5.61 0.45 1.23e-7 Bone mineral density; TGCT cis rs7617773 0.743 rs13081633 chr3:48357281 A/G cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs9916302 0.861 rs4795376 chr17:37669043 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.88 -0.4 3.2e-6 Glomerular filtration rate (creatinine); TGCT cis rs916888 0.821 rs70600 chr17:44860021 C/T cg01570182 chr17:44337453 NA 1.01 9.1 0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.1 0.42 1.24e-6 Menopause (age at onset); TGCT cis rs9926296 0.656 rs4522419 chr16:89853307 T/C cg26513180 chr16:89883248 FANCA 0.74 7.18 0.54 5.51e-11 Vitiligo; TGCT cis rs4409675 0.527 rs12067053 chr1:28227122 T/G cg23691781 chr1:28212827 C1orf38 0.26 5.44 0.44 2.76e-7 Corneal astigmatism; TGCT cis rs367943 1.000 rs367943 chr5:112809728 C/T cg12552261 chr5:112820674 MCC 0.26 4.87 0.4 3.37e-6 Type 2 diabetes; TGCT cis rs600231 0.706 rs11227221 chr11:65319265 T/C cg17120908 chr11:65337727 SSSCA1 0.54 5.07 0.41 1.4e-6 Bone mineral density; TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg24675658 chr1:53192096 ZYG11B -0.76 -9.17 -0.64 1.25e-15 Monocyte count; TGCT cis rs988712 0.587 rs117567901 chr11:27706040 T/C cg10635145 chr11:27742435 BDNF -0.43 -6.14 -0.48 1.04e-8 Obesity; TGCT cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg12310025 chr6:25882481 NA 0.53 4.83 0.4 4.01e-6 Intelligence (multi-trait analysis); TGCT cis rs6598955 0.543 rs6698557 chr1:26561220 G/C cg24519413 chr1:26490540 NA -0.25 -4.65 -0.39 8.5e-6 Obesity-related traits; TGCT cis rs2243480 1.000 rs466983 chr7:65520496 T/G cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7726839 0.540 rs72703078 chr5:594987 A/C cg09021430 chr5:549028 NA -0.43 -5.83 -0.46 4.57e-8 Obesity-related traits; TGCT cis rs1129187 0.902 rs6907751 chr6:42944850 C/T cg05552183 chr6:42928497 GNMT 0.58 5.17 0.42 8.97e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4746818 1.000 rs4342912 chr10:70959282 T/C cg04149295 chr10:70884716 VPS26A 0.78 5.32 0.43 4.7e-7 Left atrial antero-posterior diameter; TGCT cis rs35771425 0.518 rs1055565 chr1:211605697 G/A cg26515805 chr1:211431828 RCOR3 -0.44 -5.04 -0.41 1.64e-6 Educational attainment (years of education); TGCT cis rs6071524 0.508 rs2244193 chr20:37387985 A/G cg09937324 chr20:37376998 ACTR5 0.54 4.45 0.37 1.91e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs28595532 0.841 rs116587722 chr4:119790517 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.07 0.59 5.05e-13 Cannabis dependence symptom count; TGCT cis rs7267979 1.000 rs6050602 chr20:25401203 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.869 rs1796521 chr6:26421392 T/C cg26531700 chr6:26746687 NA -0.5 -4.82 -0.4 4.06e-6 Intelligence (multi-trait analysis); TGCT cis rs9921338 0.961 rs4780358 chr16:11374212 G/T cg00044050 chr16:11439710 C16orf75 -0.85 -6.07 -0.48 1.47e-8 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs7926906 0.688 rs2213085 chr11:90528586 A/G cg26138821 chr11:89956704 CHORDC1 -0.44 -4.6 -0.38 1.04e-5 Intelligence (multi-trait analysis); TGCT cis rs4072705 0.615 rs7028021 chr9:127249022 A/G cg13476313 chr9:127244764 NR5A1 0.29 4.94 0.41 2.45e-6 Menarche (age at onset); TGCT cis rs6860806 0.661 rs28472559 chr5:131581611 G/A cg24060327 chr5:131705240 SLC22A5 -0.55 -5.61 -0.45 1.27e-7 Breast cancer; TGCT cis rs295140 1.000 rs13028959 chr2:201185919 C/A cg04283868 chr2:201171347 SPATS2L 0.65 6.67 0.51 7.76e-10 QT interval; TGCT cis rs858239 0.539 rs2141306 chr7:23191664 G/A cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs796364 0.568 rs11890894 chr2:201072055 C/T cg04283868 chr2:201171347 SPATS2L -0.55 -4.65 -0.39 8.28e-6 Schizophrenia; TGCT cis rs78487399 0.710 rs72879276 chr2:43627101 T/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -4.87 -0.4 3.39e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1862618 0.853 rs832583 chr5:56178217 A/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs7100689 0.516 rs3862532 chr10:82015725 A/C cg01528321 chr10:82214614 TSPAN14 0.71 6.76 0.52 4.92e-10 Post bronchodilator FEV1; TGCT cis rs7666738 0.753 rs17483788 chr4:98985623 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1511802 0.666 rs4862663 chr4:187119228 T/A cg19358738 chr4:186734530 SORBS2 0.17 4.55 0.38 1.27e-5 Blood protein levels; TGCT cis rs7617480 0.648 rs6766238 chr3:48801929 G/A cg07636037 chr3:49044803 WDR6 0.78 6.5 0.5 1.73e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9372498 0.536 rs62424172 chr6:118777533 C/A cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs2228479 0.850 rs12598316 chr16:89916600 C/A cg06558623 chr16:89946397 TCF25 0.56 4.86 0.4 3.54e-6 Skin colour saturation; TGCT cis rs2594989 0.945 rs2594969 chr3:11353399 C/G cg00170343 chr3:11313890 ATG7 0.62 4.69 0.39 7.07e-6 Circulating chemerin levels; TGCT cis rs858239 0.698 rs858295 chr7:23245569 A/G cg05407003 chr7:23246146 NA -0.29 -4.59 -0.38 1.05e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs2282802 0.685 rs6867870 chr5:139641896 C/A cg01081189 chr5:139537190 NA 0.29 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs6490294 0.904 rs12423126 chr12:112429469 C/G cg10833066 chr12:111807467 FAM109A 0.36 5.11 0.42 1.17e-6 Mean platelet volume; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg25151919 chr3:44754333 ZNF502 -0.45 -5.31 -0.43 4.93e-7 Depressive symptoms; TGCT cis rs7659604 0.791 rs57316471 chr4:122663939 A/G cg06713675 chr4:122721982 EXOSC9 -0.5 -6.45 -0.5 2.23e-9 Type 2 diabetes; TGCT cis rs67311347 0.524 rs7649168 chr3:40356158 T/C cg17264618 chr3:40429014 ENTPD3 0.3 4.48 0.37 1.69e-5 Renal cell carcinoma; TGCT cis rs6714710 0.535 rs13006932 chr2:98370698 T/A cg26665480 chr2:98280029 ACTR1B 0.69 6.27 0.49 5.37e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs11578119 0.933 rs7511715 chr1:170432995 T/C cg09767346 chr1:170501363 GORAB 0.71 5.68 0.45 9.07e-8 Male-pattern baldness; TGCT cis rs1865760 0.566 rs3752420 chr6:26027135 G/A cg16482183 chr6:26056742 HIST1H1C 0.59 5.14 0.42 1.04e-6 Height; TGCT cis rs854765 0.583 rs4257260 chr17:17857003 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs7914558 0.966 rs3758543 chr10:104944744 C/G cg04362960 chr10:104952993 NT5C2 0.61 5.47 0.44 2.42e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6866344 0.697 rs56159071 chr5:178127246 T/A cg03877680 chr5:178157825 ZNF354A 0.73 5.72 0.46 7.46e-8 Neutrophil percentage of white cells; TGCT cis rs4972806 0.739 rs10834 chr2:177042087 A/G cg03152288 chr2:177042942 NA 0.6 4.87 0.4 3.31e-6 IgG glycosylation; TGCT cis rs8072100 0.701 rs6503807 chr17:45772932 T/C cg08085267 chr17:45401833 C17orf57 -0.43 -4.82 -0.4 4.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1903068 0.752 rs28517654 chr4:55993468 T/C cg16572876 chr4:56024045 NA 0.42 4.74 0.39 5.64e-6 Endometriosis; TGCT cis rs875971 1.000 rs12532998 chr7:65967459 A/C cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg07424592 chr7:64974309 NA -1.26 -7.79 -0.57 2.25e-12 Diabetic kidney disease; TGCT cis rs7605378 0.528 rs1704190 chr2:200760629 G/A cg17644776 chr2:200775616 C2orf69 0.34 7.46 0.56 1.31e-11 Osteoporosis; TGCT cis rs250677 0.687 rs40149 chr5:148444275 A/T cg18129178 chr5:148520854 ABLIM3 -0.44 -6.57 -0.51 1.27e-9 Breast cancer; TGCT cis rs10875595 0.836 rs2879202 chr5:140668375 G/T cg24830062 chr5:140700576 TAF7 -0.55 -4.6 -0.38 1.04e-5 Pulmonary function decline; TGCT cis rs6912958 0.559 rs499373 chr6:88042062 A/T cg10393598 chr6:87862264 NA -0.31 -4.51 -0.38 1.5e-5 Monocyte percentage of white cells; TGCT cis rs1023500 0.573 rs133374 chr22:42465941 G/A cg05082376 chr22:42548792 NA -0.22 -5.41 -0.44 3.18e-7 Schizophrenia; TGCT cis rs6570726 0.537 rs1280279 chr6:145884048 G/T cg13319975 chr6:146136371 FBXO30 -0.64 -4.91 -0.4 2.79e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs7949030 0.596 rs71490394 chr11:62370155 G/A cg13298116 chr11:62369859 EML3;MTA2 0.64 9.48 0.65 2.35e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.840 rs2234059 chr22:41777913 T/C cg06481639 chr22:41940642 POLR3H -0.72 -6.52 -0.51 1.61e-9 Vitiligo; TGCT cis rs992157 0.798 rs10206064 chr2:219157959 T/C cg00012203 chr2:219082015 ARPC2 0.81 8.08 0.59 4.97e-13 Colorectal cancer; TGCT cis rs7586879 0.639 rs2033656 chr2:25100902 C/G cg15423357 chr2:25149977 NA 0.5 4.75 0.39 5.43e-6 Body mass index; TGCT cis rs9325144 0.647 rs11169222 chr12:39105210 C/T cg10518543 chr12:38710700 ALG10B -0.49 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs9303401 0.659 rs62083362 chr17:56846464 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT trans rs4765905 0.500 rs3794297 chr12:2338396 C/T cg13866577 chr1:66797481 PDE4B -0.5 -6.85 -0.52 3.03e-10 Schizophrenia; TGCT cis rs1865760 0.566 rs2794720 chr6:26087202 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs2836974 0.627 rs9981301 chr21:40686078 G/C cg06238570 chr21:40685208 BRWD1 -0.83 -9.27 -0.64 7.25e-16 Cognitive function; TGCT cis rs7208859 0.562 rs216408 chr17:28907757 C/G cg04154034 chr17:28927549 LRRC37B2 -0.8 -4.99 -0.41 1.99e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11105298 0.891 rs10777162 chr12:89830523 A/G cg00757033 chr12:89920650 WDR51B 0.31 4.83 0.4 3.92e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs12908161 0.650 rs306206 chr15:85388653 A/G cg11189052 chr15:85197271 WDR73 0.64 5.16 0.42 9.65e-7 Schizophrenia; TGCT cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2486288 0.586 rs12909625 chr15:45572053 C/A cg26924012 chr15:45694286 SPATA5L1 -0.79 -7.73 -0.57 3.24e-12 Glomerular filtration rate; TGCT cis rs2404602 0.647 rs11632765 chr15:76974261 A/T cg22467129 chr15:76604101 ETFA -0.45 -4.58 -0.38 1.11e-5 Blood metabolite levels; TGCT cis rs4595586 0.525 rs7136425 chr12:39376005 C/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7949030 0.695 rs11231161 chr11:62378221 A/G cg11742103 chr11:62369870 EML3;MTA2 0.62 9.29 0.64 6.77e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1215050 0.791 rs1530904 chr4:98805436 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs769267 0.930 rs1054284 chr19:19616953 T/G cg03709012 chr19:19516395 GATAD2A 0.74 6.22 0.49 7.04e-9 Tonsillectomy; TGCT cis rs7582180 0.614 rs4149518 chr2:101013649 A/G cg14675211 chr2:100938903 LONRF2 0.5 4.77 0.39 5.18e-6 Intelligence (multi-trait analysis); TGCT cis rs11677370 0.574 rs10209122 chr2:3871186 C/A cg17052675 chr2:3827356 NA -0.39 -5.69 -0.45 8.81e-8 Type 2 diabetes; TGCT cis rs28595532 0.920 rs115240535 chr4:119745395 G/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs1476679 1.000 rs1476679 chr7:100004446 C/T cg13334819 chr7:99746414 C7orf59 0.64 5.51 0.44 1.98e-7 Alzheimer's disease (late onset); TGCT cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7917772 0.505 rs61869211 chr10:104449836 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.67 5.76 0.46 6.21e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3733585 0.781 rs4292328 chr4:9970962 C/T cg00071950 chr4:10020882 SLC2A9 -0.65 -8.23 -0.59 2.24e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs877282 1.000 rs10904552 chr10:774326 A/G cg17470449 chr10:769945 NA 0.3 4.8 0.4 4.4e-6 Uric acid levels; TGCT cis rs524281 0.861 rs11227415 chr11:65885459 C/T cg00563793 chr11:65837595 PACS1 -0.61 -5.21 -0.42 7.79e-7 Electroencephalogram traits; TGCT cis rs10504229 0.683 rs11775568 chr8:58133762 G/A cg21724239 chr8:58056113 NA 0.47 5.14 0.42 1.05e-6 Developmental language disorder (linguistic errors); TGCT cis rs7824557 0.527 rs2572369 chr8:11238597 C/T cg21775007 chr8:11205619 TDH -0.68 -6.67 -0.51 7.76e-10 Retinal vascular caliber; TGCT cis rs9467773 1.000 rs9295695 chr6:26528250 C/T cg15659132 chr6:26577336 NA -0.86 -12.17 -0.74 6.64e-23 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs431076 chr7:65600320 A/C cg18252515 chr7:66147081 NA -1.21 -7.89 -0.58 1.36e-12 Diabetic kidney disease; TGCT cis rs7659604 0.967 rs28529384 chr4:122664215 T/C cg19748678 chr4:122722346 EXOSC9 0.57 5.54 0.45 1.69e-7 Type 2 diabetes; TGCT cis rs77106637 0.860 rs75896506 chr11:72429579 G/A cg03713592 chr11:72463424 ARAP1 1.23 9.23 0.64 9.14e-16 Type 2 diabetes; TGCT cis rs644799 1.000 rs473148 chr11:95628606 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.84 9.8 0.66 3.92e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6426558 0.537 rs689094 chr1:227308909 G/A cg10327440 chr1:227177885 CDC42BPA 0.58 6.91 0.53 2.21e-10 Neutrophil percentage of white cells; TGCT cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs8177253 0.898 rs8177258 chr3:133480387 C/A cg08439880 chr3:133502540 NA -0.31 -5.91 -0.47 3.1e-8 Iron status biomarkers; TGCT cis rs7226408 0.857 rs55731927 chr18:34731431 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs360798 0.512 rs2215870 chr2:63132342 C/G cg17519650 chr2:63277830 OTX1 0.55 4.76 0.39 5.33e-6 Coronary artery disease; TGCT cis rs13326165 0.616 rs82825 chr3:52471942 G/A cg27565382 chr3:53032988 SFMBT1 -0.37 -4.89 -0.4 3.04e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs2468186 0.583 rs1905775 chr8:120088835 A/G cg02248809 chr8:120845432 TAF2 -0.45 -4.83 -0.4 4.01e-6 Osteoprotegerin levels; TGCT cis rs875971 1.000 rs3981131 chr7:65951677 A/G cg11764359 chr7:65958608 NA 0.61 5.59 0.45 1.37e-7 Aortic root size; TGCT cis rs10984561 0.881 rs10984557 chr9:122249690 C/T cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs7647973 0.667 rs11721148 chr3:49646669 G/A cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs10832169 1.000 rs11023059 chr11:14064392 A/G cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs7246657 0.943 rs10415024 chr19:37814724 A/G cg18154014 chr19:37997991 ZNF793 0.98 6.49 0.5 1.87e-9 Coronary artery calcification; TGCT cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg07636037 chr3:49044803 WDR6 0.95 10.17 0.67 4.99e-18 Parkinson's disease; TGCT cis rs6988636 1.000 rs9987357 chr8:124187620 T/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9916302 0.861 rs11078913 chr17:37671714 G/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.92 -0.4 2.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs1552244 0.882 rs34779351 chr3:10021801 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT trans rs7726839 0.561 rs4957050 chr5:579066 A/C cg11887960 chr12:57824829 NA 0.96 8.01 0.58 7.22e-13 Obesity-related traits; TGCT cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg13695892 chr22:41940480 POLR3H 0.92 8.79 0.62 1.04e-14 Vitiligo; TGCT cis rs4689592 0.546 rs907523 chr4:7052777 A/G cg06697600 chr4:7070879 GRPEL1 -0.46 -4.66 -0.39 7.87e-6 Monocyte percentage of white cells; TGCT cis rs7772486 0.875 rs7739418 chr6:146359188 G/A cg23711669 chr6:146136114 FBXO30 0.85 9.44 0.65 2.92e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 0.712 rs258319 chr16:89732024 A/T cg04287289 chr16:89883240 FANCA -0.54 -4.96 -0.41 2.23e-6 Vitiligo; TGCT cis rs35306767 0.953 rs11253521 chr10:976416 G/C cg20503657 chr10:835505 NA 0.59 8.4 0.6 8.84e-14 Eosinophil percentage of granulocytes; TGCT cis rs8078723 1.000 rs59925331 chr17:38169273 C/G cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7772486 0.790 rs9403749 chr6:146162239 A/G cg23711669 chr6:146136114 FBXO30 0.96 11.46 0.72 3.44e-21 Lobe attachment (rater-scored or self-reported); TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg01516881 chr6:292596 DUSP22 -0.76 -7.92 -0.58 1.16e-12 Menopause (age at onset); TGCT cis rs12484776 0.677 rs6001795 chr22:40530922 G/A cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs9910055 0.529 rs170637 chr17:42186868 C/T cg13607699 chr17:42295918 UBTF -0.64 -5.24 -0.43 6.82e-7 Total body bone mineral density; TGCT cis rs59197085 0.636 rs3823480 chr7:128468881 G/A cg00260937 chr7:128520193 KCP 0.47 4.95 0.41 2.36e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs1577917 0.740 rs2758842 chr6:86308731 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.52 -4.76 -0.39 5.23e-6 Response to antipsychotic treatment; TGCT cis rs9814567 1.000 rs7428326 chr3:134251184 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7666738 0.830 rs17027198 chr4:98991085 G/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs12069356 chr1:154849771 C/T cg24250549 chr1:154909240 PMVK 0.59 5.87 0.47 3.7e-8 Prostate cancer; TGCT cis rs72781680 0.898 rs72796166 chr2:23939311 G/C cg08917208 chr2:24149416 ATAD2B 0.9 5.58 0.45 1.46e-7 Lymphocyte counts; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs1062177 1.000 rs2964576 chr5:151150602 T/G cg00977110 chr5:151150581 G3BP1 0.4 4.57 0.38 1.16e-5 Preschool internalizing problems; TGCT cis rs6495367 1.000 rs755362 chr15:79376601 C/T cg17916960 chr15:79447300 NA -0.35 -5.03 -0.41 1.67e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs12989701 0.740 rs28434131 chr2:127850292 A/G cg08168897 chr2:127865431 BIN1 0.57 6.04 0.48 1.69e-8 Alzheimer's disease (late onset); TGCT cis rs7655841 0.773 rs6812361 chr4:129899758 G/A cg26347359 chr4:129759716 PHF17 0.42 4.9 0.4 2.97e-6 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs931608 0.569 rs17461312 chr19:22554107 G/T cg15554505 chr19:22123728 NA -0.61 -4.71 -0.39 6.61e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs8084125 0.832 rs62105182 chr18:74951407 T/C cg15443732 chr18:74961078 GALR1 0.48 4.7 0.39 6.76e-6 Obesity-related traits; TGCT cis rs2288073 0.965 rs10173949 chr2:24410256 A/C cg05570707 chr2:24270316 C2orf44 -0.5 -4.49 -0.37 1.58e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs6460942 1.000 rs79964328 chr7:12319392 A/C cg06484146 chr7:12443880 VWDE -0.54 -4.55 -0.38 1.26e-5 Coronary artery disease; TGCT cis rs17345786 0.520 rs12638134 chr3:101334609 G/T cg11279151 chr3:101281821 RG9MTD1 -0.22 -4.44 -0.37 1.94e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.519 rs7294292 chr12:38349540 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.33e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg11279151 chr3:101281821 RG9MTD1 0.33 7.05 0.54 1.09e-10 Colorectal cancer; TGCT cis rs2075371 0.933 rs1901214 chr7:133945108 C/T cg11752832 chr7:134001865 SLC35B4 -0.69 -5.97 -0.47 2.32e-8 Mean platelet volume; TGCT cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs77372450 0.551 rs62390781 chr5:157061507 G/A cg19063654 chr5:156516798 HAVCR2 -0.37 -4.43 -0.37 2.01e-5 Bipolar disorder (body mass index interaction); TGCT trans rs1814175 0.647 rs61306292 chr11:49856040 G/C cg03929089 chr4:120376271 NA -0.71 -7.92 -0.58 1.16e-12 Height; TGCT cis rs854765 0.647 rs2955365 chr17:18023897 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.57 0.56 7.33e-12 Total body bone mineral density; TGCT cis rs6540559 0.673 rs58637469 chr1:209971480 T/A cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs9388451 0.839 rs980014 chr6:126068001 T/G cg10911889 chr6:126070802 HEY2 0.57 6.06 0.48 1.51e-8 Brugada syndrome; TGCT cis rs8072100 0.967 rs7219303 chr17:45737701 A/G cg08085267 chr17:45401833 C17orf57 0.42 4.6 0.38 1.04e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1005224 0.963 rs11626062 chr14:76136329 T/C cg04684003 chr14:76127793 TTLL5;C14orf1 -0.61 -5.73 -0.46 7.21e-8 Large artery stroke; TGCT cis rs12421382 0.543 rs11213094 chr11:109357926 G/A cg16359550 chr11:109292809 C11orf87 0.68 7.23 0.54 4.37e-11 Schizophrenia; TGCT cis rs17221829 0.673 rs11018676 chr11:89362728 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs6952808 0.595 rs2398705 chr7:2164995 G/A cg04267008 chr7:1944627 MAD1L1 -0.38 -5.19 -0.42 8.33e-7 Bipolar disorder and schizophrenia; TGCT cis rs986417 0.748 rs4901986 chr14:60969333 T/C cg27398547 chr14:60952738 C14orf39 1.49 10.81 0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs6598955 0.671 rs12068212 chr1:26612935 C/T cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs5750830 0.594 rs5757647 chr22:39775047 C/A cg24399712 chr22:39784796 NA -0.95 -11.01 -0.7 4.37e-20 Intelligence (multi-trait analysis); TGCT cis rs739401 0.527 rs423236 chr11:3065916 C/T cg25174290 chr11:3078921 CARS 0.47 4.44 0.37 1.99e-5 Longevity; TGCT cis rs8179 0.514 rs11773884 chr7:92285123 A/G cg15732164 chr7:92237376 CDK6 -0.28 -5.15 -0.42 9.96e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs12762955 0.561 rs7075141 chr10:1091195 C/T cg18964960 chr10:1102726 WDR37 -0.56 -4.85 -0.4 3.65e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs7818688 0.697 rs78777150 chr8:95984411 C/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs11122272 0.735 rs2749704 chr1:231526243 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs425277 0.606 rs16824792 chr1:2039521 G/T cg24578937 chr1:2090814 PRKCZ -0.22 -5.26 -0.43 6.08e-7 Height; TGCT cis rs9467711 0.606 rs12176317 chr6:26372786 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs75686122 0.892 rs17234986 chr8:104729301 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs2535633 0.631 rs2710326 chr3:52995444 T/C cg10802521 chr3:52805072 NEK4 0.56 6.02 0.48 1.86e-8 Body mass index; TGCT cis rs5750830 0.645 rs4821890 chr22:39777523 G/A cg01416388 chr22:39784598 NA -0.63 -6.66 -0.51 8.09e-10 Intelligence (multi-trait analysis); TGCT cis rs11971779 0.941 rs7800795 chr7:139080348 A/G cg07862535 chr7:139043722 LUC7L2 0.79 5.8 0.46 5.13e-8 Diisocyanate-induced asthma; TGCT cis rs7666738 0.753 rs13122897 chr4:98936185 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3806843 0.932 rs2563257 chr5:140140529 A/G cg19875535 chr5:140030758 IK -0.36 -6.17 -0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs3749237 0.964 rs11717463 chr3:49808981 C/T cg03060546 chr3:49711283 APEH 0.73 7.1 0.54 8.41e-11 Resting heart rate; TGCT cis rs7698623 0.850 rs4693192 chr4:88797913 T/C cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs751728 1.000 rs943477 chr6:33750931 T/C cg00334056 chr6:33755658 LEMD2 -0.25 -4.52 -0.38 1.44e-5 Crohn's disease; TGCT cis rs7829975 0.510 rs332037 chr8:8722675 C/T cg06636001 chr8:8085503 FLJ10661 0.68 6.26 0.49 5.89e-9 Mood instability; TGCT cis rs1371867 0.810 rs2860518 chr8:101238120 G/T cg06636551 chr8:101224915 SPAG1 0.45 6.15 0.48 9.76e-9 Atrioventricular conduction; TGCT cis rs6582630 0.502 rs10880450 chr12:38440294 G/C cg26384229 chr12:38710491 ALG10B 0.83 7.46 0.56 1.32e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs250677 0.958 rs36070 chr5:148417240 T/C cg18129178 chr5:148520854 ABLIM3 -0.4 -5.63 -0.45 1.17e-7 Breast cancer; TGCT cis rs763121 1.000 rs86796 chr22:38881454 A/C cg06022373 chr22:39101656 GTPBP1 -0.71 -6.85 -0.52 3.03e-10 Menopause (age at onset); TGCT cis rs7264396 0.635 rs6060673 chr20:34482396 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.29 5.01 0.41 1.85e-6 Total cholesterol levels; TGCT cis rs7909074 0.798 rs10900126 chr10:45386322 G/T cg04218760 chr10:45406644 TMEM72 -0.28 -5.49 -0.44 2.15e-7 Mean corpuscular volume; TGCT cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg05896524 chr21:47604654 C21orf56 -0.43 -4.54 -0.38 1.31e-5 Testicular germ cell tumor; TGCT cis rs916888 0.610 rs199452 chr17:44801340 C/T cg01570182 chr17:44337453 NA 0.76 7.36 0.55 2.22e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6674176 0.660 rs6680421 chr1:44408969 A/C cg13606994 chr1:44402422 ARTN 0.49 5.38 0.44 3.57e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1355223 0.583 rs1396880 chr11:34870552 C/T cg11058730 chr11:34937778 PDHX;APIP -0.76 -8.22 -0.59 2.3e-13 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs911263 0.603 rs2064911 chr14:68807298 T/C cg18825221 chr14:68749962 RAD51L1 0.22 4.43 0.37 2.01e-5 Primary biliary cholangitis; TGCT cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg03060546 chr3:49711283 APEH 0.5 4.72 0.39 6.38e-6 Menarche (age at onset); TGCT cis rs7100689 0.646 rs10400045 chr10:82077032 A/G cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs250677 0.522 rs10477400 chr5:148359598 T/C cg18129178 chr5:148520854 ABLIM3 0.38 4.95 0.41 2.33e-6 Breast cancer; TGCT cis rs12908161 1.000 rs12903134 chr15:85337699 T/A cg12863693 chr15:85201151 NMB 0.42 5.06 0.41 1.5e-6 Schizophrenia; TGCT cis rs11190604 0.767 rs7076606 chr10:102192267 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.79 0.4 4.69e-6 Palmitoleic acid (16:1n-7) levels; TGCT trans rs1496653 0.602 rs35402533 chr3:23357291 T/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg27535305 chr1:53392650 SCP2 -0.28 -5.93 -0.47 2.85e-8 Monocyte count; TGCT cis rs3824867 0.920 rs7108143 chr11:47453722 T/G cg20307385 chr11:47447363 PSMC3 -0.68 -5.78 -0.46 5.75e-8 Mean corpuscular hemoglobin; TGCT cis rs7635838 0.617 rs184700 chr3:11293061 A/G cg00170343 chr3:11313890 ATG7 0.66 6.53 0.51 1.52e-9 HDL cholesterol; TGCT cis rs3806933 0.522 rs12521169 chr5:110448313 G/A cg04022379 chr5:110408740 TSLP 0.63 6.52 0.51 1.6e-9 Eosinophilic esophagitis; TGCT cis rs838147 0.505 rs1688264 chr19:49209560 T/G cg00822241 chr19:49201468 FUT2 0.28 4.54 0.38 1.32e-5 Dietary macronutrient intake; TGCT cis rs6088580 0.634 rs4911420 chr20:32998654 A/G cg06115741 chr20:33292138 TP53INP2 -0.56 -5.03 -0.41 1.67e-6 Glomerular filtration rate (creatinine); TGCT cis rs4665809 0.793 rs6546715 chr2:26261520 G/A cg04944784 chr2:26401820 FAM59B -0.67 -5.98 -0.47 2.23e-8 Gut microbiome composition (summer); TGCT trans rs7698623 0.850 rs1381958 chr4:88796785 T/C cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs7617480 0.648 rs9284885 chr3:48883100 A/C cg07636037 chr3:49044803 WDR6 0.77 6.4 0.5 2.91e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs6163 0.508 rs12776506 chr10:104532828 A/G cg05855489 chr10:104503620 C10orf26 0.6 4.72 0.39 6.21e-6 Waist circumference;Hip circumference; TGCT trans rs2727020 1.000 rs2727020 chr11:49111407 C/G cg03929089 chr4:120376271 NA 0.71 7.76 0.57 2.74e-12 Coronary artery disease; TGCT cis rs7259965 0.582 rs3895941 chr19:41531212 T/C cg20630647 chr19:41531805 NA 0.39 6.2 0.49 7.68e-9 Midgestational circulating levels of PBDEs;Midgestational circulating levels of organochlorine pesticides; TGCT trans rs877282 1.000 rs12773872 chr10:771939 T/C cg22713356 chr15:30763199 NA 1.14 10.05 0.67 9.58e-18 Uric acid levels; TGCT cis rs10791323 0.604 rs2723598 chr11:133711652 G/A cg03690763 chr11:133734501 NA -0.31 -4.79 -0.39 4.72e-6 Childhood ear infection; TGCT cis rs6750047 0.573 rs162331 chr2:38319594 C/T cg07380506 chr2:38303506 CYP1B1 0.59 5.48 0.44 2.32e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs9790314 0.967 rs457272 chr3:161096746 A/G cg03342759 chr3:160939853 NMD3 -0.44 -4.49 -0.37 1.64e-5 Morning vs. evening chronotype; TGCT cis rs1371867 0.875 rs1788168 chr8:101324960 G/T cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs7267979 0.738 rs2892409 chr20:25638138 C/T cg03522245 chr20:25566470 NINL 0.53 5.43 0.44 2.81e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9650657 0.537 rs11250092 chr8:10786543 A/G cg27411982 chr8:10470053 RP1L1 0.24 5.2 0.42 8.04e-7 Neuroticism; TGCT cis rs1045714 0.895 rs73035504 chr7:2642878 G/A cg17215154 chr7:2644645 IQCE 0.28 4.92 0.4 2.75e-6 Urate levels in lean individuals; TGCT cis rs56104184 0.887 rs4801778 chr19:49370609 G/T cg17863274 chr19:49399704 TULP2 -0.36 -5.18 -0.42 8.68e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4886920 0.563 rs8040813 chr15:78073289 A/G cg25212270 chr15:78015279 NA 0.23 4.81 0.4 4.26e-6 Neuroticism; TGCT cis rs617791 0.530 rs10896073 chr11:65762814 T/C cg09783858 chr11:65769428 EIF1AD;BANF1 0.5 4.56 0.38 1.2e-5 Breast cancer; TGCT cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg11062466 chr8:58055876 NA 0.46 4.89 0.4 3.07e-6 Developmental language disorder (linguistic errors); TGCT cis rs9486719 0.948 rs2499817 chr6:96878321 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs4819052 0.885 rs28576202 chr21:46674684 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11648796 0.757 rs3809665 chr16:764520 G/C cg00908189 chr16:619842 PIGQ 0.7 5.7 0.46 8.1e-8 Height; TGCT cis rs10501293 0.675 rs10768912 chr11:43034756 C/T cg03447554 chr11:43094025 NA 0.44 6.29 0.49 5.05e-9 Cognitive performance; TGCT cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg11375102 chr16:1583810 IFT140;TMEM204 -0.31 -5.51 -0.44 2e-7 Coronary artery disease; TGCT cis rs589249 0.889 rs1002655 chr1:37192677 C/G cg04012535 chr1:37176647 NA 0.32 4.92 0.4 2.74e-6 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs1371867 0.846 rs1660312 chr8:101330634 C/G cg06002616 chr8:101225028 SPAG1 -0.57 -6.63 -0.51 9.18e-10 Atrioventricular conduction; TGCT cis rs7635838 0.617 rs347587 chr3:11287155 A/G cg00170343 chr3:11313890 ATG7 -0.65 -6.54 -0.51 1.47e-9 HDL cholesterol; TGCT cis rs36051895 0.659 rs10974944 chr9:5070831 C/G cg02405213 chr9:5042618 JAK2 -0.74 -8.69 -0.62 1.76e-14 Pediatric autoimmune diseases; TGCT cis rs3806843 0.576 rs246046 chr5:140329264 T/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs78461346 1.000 rs78461346 chr17:80524184 G/A cg15014069 chr17:80540666 FOXK2 0.4 5.04 0.41 1.62e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT trans rs1415174 0.877 rs2065908 chr1:87847053 T/C cg23065576 chr20:25207247 ENTPD6 -0.27 -6.8 -0.52 3.88e-10 Breast cancer; TGCT cis rs9560113 0.960 rs1163862 chr13:112174319 C/T cg14154082 chr13:112174009 NA 0.35 4.93 0.4 2.59e-6 Menarche (age at onset); TGCT cis rs9300255 0.544 rs1790130 chr12:123701270 A/C cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs9921338 0.961 rs4390613 chr16:11422836 T/C cg00044050 chr16:11439710 C16orf75 0.89 6.53 0.51 1.56e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs7666738 0.715 rs61114099 chr4:98931270 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.85 -10.01 -0.67 1.2e-17 Urate levels; TGCT cis rs2439831 0.850 rs28590651 chr15:44113016 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.27 0.49 5.48e-9 Lung cancer in ever smokers; TGCT cis rs4689388 0.926 rs10010131 chr4:6292915 A/G cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7727544 1.000 rs7727038 chr5:131590257 C/T cg24060327 chr5:131705240 SLC22A5 -0.62 -6.48 -0.5 1.97e-9 Blood metabolite levels; TGCT trans rs7726839 0.507 rs56282020 chr5:596701 T/C cg11887960 chr12:57824829 NA 1.21 9.64 0.65 9.42e-17 Obesity-related traits; TGCT cis rs523522 0.962 rs3759394 chr12:120933173 C/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs6840360 0.642 rs7657670 chr4:152353375 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs1334894 0.901 rs1977655 chr6:35521702 G/A cg24281267 chr6:35479648 TULP1 -0.44 -4.54 -0.38 1.29e-5 Coronary artery disease; TGCT cis rs2456568 0.571 rs12807496 chr11:93693064 A/G cg17595323 chr11:93583763 C11orf90 0.38 4.62 0.38 9.46e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3096299 0.900 rs4785666 chr16:89462771 C/G cg06640241 chr16:89574553 SPG7 0.61 5.76 0.46 6.36e-8 Multiple myeloma (IgH translocation); TGCT cis rs4819852 0.958 rs1034564 chr22:19984013 A/G cg07821417 chr22:19972146 ARVCF -0.19 -4.73 -0.39 5.97e-6 Pulse pressure; TGCT cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.79e-6 Obesity-related traits; TGCT cis rs854765 0.822 rs1889014 chr17:17767165 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.41 -0.44 3.16e-7 Total body bone mineral density; TGCT cis rs10489525 0.528 rs360604 chr1:115390019 G/A cg12756093 chr1:115239321 AMPD1 0.36 4.44 0.37 1.94e-5 Autism; TGCT cis rs9581857 0.685 rs9319372 chr13:28042796 C/T cg22138327 chr13:27999177 GTF3A -0.73 -4.98 -0.41 2.07e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7605378 0.567 rs717915 chr2:200714766 C/T cg17644776 chr2:200775616 C2orf69 0.34 7.39 0.55 1.88e-11 Osteoporosis; TGCT cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs6570726 0.791 rs6914203 chr6:145899975 C/A cg23711669 chr6:146136114 FBXO30 0.85 9.24 0.64 8.9e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4919694 0.901 rs12251035 chr10:104671459 A/C cg04362960 chr10:104952993 NT5C2 1.06 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs3771570 0.901 rs4675964 chr2:242324760 A/C cg21155796 chr2:242212141 HDLBP 0.84 6.32 0.49 4.39e-9 Prostate cancer; TGCT cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.96 0.41 2.29e-6 Prudent dietary pattern; TGCT cis rs9916302 0.605 rs12938099 chr17:37612910 T/G cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs6032067 0.516 rs1883829 chr20:43891253 G/C cg16667508 chr20:43936853 MATN4;RBPJL -0.36 -5.61 -0.45 1.27e-7 Blood protein levels; TGCT cis rs7666738 0.716 rs114187620 chr4:98819534 T/A cg05340658 chr4:99064831 C4orf37 0.51 6.03 0.48 1.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs981844 0.683 rs4696191 chr4:154740668 G/A cg14289246 chr4:154710475 SFRP2 -1.0 -9.26 -0.64 7.7e-16 Response to statins (LDL cholesterol change); TGCT cis rs13191362 1.000 rs13193282 chr6:163015442 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1008375 0.800 rs28754811 chr4:17612312 C/T cg16339924 chr4:17578868 LAP3 0.68 5.56 0.45 1.56e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.714 rs2051540 chr6:25947197 T/C cg03517284 chr6:25882590 NA -0.69 -6.22 -0.49 7.11e-9 Intelligence (multi-trait analysis); TGCT cis rs2760061 0.626 rs596675 chr1:228117892 G/A cg02753203 chr1:228287806 NA -0.34 -6.64 -0.51 8.69e-10 Diastolic blood pressure; TGCT cis rs477895 0.838 rs12798333 chr11:64012784 G/A cg23719950 chr11:63933701 MACROD1 -0.69 -5.74 -0.46 6.94e-8 Mean platelet volume; TGCT cis rs2439831 1.000 rs471229 chr15:43733994 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.639 rs757379 chr17:29724557 G/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.83 0.46 4.57e-8 Hip circumference; TGCT cis rs9858542 0.953 rs9818590 chr3:49525096 A/G cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs896854 0.738 rs481887 chr8:95967838 A/G cg23172400 chr8:95962367 TP53INP1 0.37 5.65 0.45 1.02e-7 Type 2 diabetes; TGCT cis rs651907 0.514 rs12636047 chr3:101434449 T/C cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.02 -0.53 1.27e-10 Colorectal cancer; TGCT cis rs72949976 0.584 rs12471432 chr2:214022893 A/T cg08319019 chr2:214017104 IKZF2 0.84 8.41 0.6 8.42e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs7172809 0.643 rs4243046 chr15:77834746 T/C cg22256960 chr15:77711686 NA -0.46 -4.62 -0.38 9.65e-6 Glucose homeostasis traits; TGCT cis rs7772486 0.875 rs10872583 chr6:146396699 G/T cg23711669 chr6:146136114 FBXO30 -0.89 -9.67 -0.66 7.76e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg03407747 chr17:6899364 ALOX12 0.51 5.78 0.46 5.67e-8 Tonsillectomy; TGCT cis rs11874712 1.000 rs13381709 chr18:43670988 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs10484885 0.878 rs72921937 chr6:90579863 T/G cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs12510870 0.599 rs16849629 chr4:74448351 G/A cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs72781680 0.752 rs56152044 chr2:23927680 A/G cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT cis rs11105298 0.786 rs10858897 chr12:89922032 C/A cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2980439 0.818 rs2948294 chr8:8094961 A/G cg15556689 chr8:8085844 FLJ10661 0.88 9.13 0.63 1.6e-15 Neuroticism; TGCT cis rs514406 0.798 rs4351588 chr1:53263826 A/T cg24675658 chr1:53192096 ZYG11B 0.89 11.49 0.72 2.91e-21 Monocyte count; TGCT cis rs36051895 0.659 rs62541540 chr9:5040080 A/G cg02405213 chr9:5042618 JAK2 -0.78 -10.74 -0.69 2.01e-19 Pediatric autoimmune diseases; TGCT cis rs3540 0.512 rs17263706 chr15:91078803 G/T cg22089800 chr15:90895588 ZNF774 0.71 7.3 0.55 3.05e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs12477438 0.765 rs1054042 chr2:99614396 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.63 -5.43 -0.44 2.89e-7 Chronic sinus infection; TGCT cis rs7246657 0.663 rs4803287 chr19:38079435 A/G cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT trans rs17685 0.712 rs59659102 chr7:75710114 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs4819052 0.851 rs2838832 chr21:46664904 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.57 -5.01 -0.41 1.84e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6992820 0.900 rs12678930 chr8:56726277 A/G cg06880721 chr8:56792545 LYN -0.55 -4.68 -0.39 7.33e-6 Mean platelet volume; TGCT cis rs68170813 0.641 rs34084719 chr7:107095227 A/G cg02696742 chr7:106810147 HBP1 -0.61 -4.98 -0.41 2.07e-6 Coronary artery disease; TGCT cis rs11098499 0.615 rs28551750 chr4:120264901 C/T cg09307838 chr4:120376055 NA 0.55 5.41 0.44 3.16e-7 Corneal astigmatism; TGCT cis rs36051895 0.623 rs10120337 chr9:5243511 G/A cg02405213 chr9:5042618 JAK2 -0.73 -9.59 -0.65 1.27e-16 Pediatric autoimmune diseases; TGCT cis rs739496 0.542 rs7399113 chr12:111792848 G/A cg10833066 chr12:111807467 FAM109A 0.44 7.52 0.56 9.58e-12 Platelet count; TGCT cis rs739496 0.579 rs57427612 chr12:112293996 C/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7439150 0.909 rs2227389 chr4:155483170 C/T cg22130008 chr4:155548532 NA -0.47 -5.8 -0.46 5.25e-8 Fibrinogen levels; TGCT cis rs2115630 0.902 rs8023276 chr15:85219638 C/T cg12863693 chr15:85201151 NMB -0.34 -4.73 -0.39 5.96e-6 P wave terminal force; TGCT cis rs7312933 0.703 rs10492388 chr12:42608001 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.53 4.62 0.38 9.51e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1215050 0.791 rs968854 chr4:98837863 T/C cg05340658 chr4:99064831 C4orf37 0.47 5.9 0.47 3.22e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1552244 0.572 rs57268864 chr3:10164233 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs4665809 1.000 rs2891490 chr2:26325927 T/C cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs28595532 0.920 rs116145969 chr4:119770908 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs1218582 0.741 rs705094 chr1:154917314 G/A cg06221963 chr1:154839813 KCNN3 -0.72 -12.31 -0.74 3.04e-23 Prostate cancer; TGCT cis rs78456975 0.600 rs72776256 chr2:1529595 C/A cg01028140 chr2:1542097 TPO -0.36 -4.63 -0.38 9.02e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7772486 0.641 rs67882056 chr6:146416301 T/C cg13319975 chr6:146136371 FBXO30 -0.65 -5.95 -0.47 2.5e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs9640161 0.750 rs4395803 chr7:150025367 A/C cg10018233 chr7:150070692 REPIN1 0.33 4.78 0.39 4.94e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs7577262 0.834 rs13028228 chr2:234843309 C/T cg04621728 chr2:234934131 NA 0.48 4.47 0.37 1.77e-5 Blood pressure measurement (cold pressor test); TGCT cis rs3809566 0.963 rs3809565 chr15:63333619 A/G cg05507819 chr15:63340323 TPM1 0.49 4.59 0.38 1.09e-5 Platelet count; TGCT cis rs4604732 1.000 rs4604732 chr1:247623872 C/T cg22475246 chr1:246888027 SCCPDH -0.59 -4.46 -0.37 1.83e-5 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); TGCT cis rs1395 0.961 rs4665963 chr2:27528692 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.47 6.18 0.48 8.68e-9 Blood metabolite levels; TGCT cis rs7089973 0.604 rs11196943 chr10:116598865 T/C cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT trans rs208520 0.690 rs207082 chr6:66773796 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -11.08 -0.71 3e-20 Exhaled nitric oxide output; TGCT cis rs8031584 0.678 rs798127 chr15:31117403 T/C cg08109568 chr15:31115862 NA 0.4 5.22 0.42 7.31e-7 Huntington's disease progression; TGCT cis rs709400 0.520 rs28583452 chr14:103938664 C/A cg26031613 chr14:104095156 KLC1 0.85 9.72 0.66 5.87e-17 Body mass index; TGCT cis rs7937682 0.889 rs564086 chr11:111501079 C/G cg09085632 chr11:111637200 PPP2R1B -1.11 -11.65 -0.72 1.21e-21 Primary sclerosing cholangitis; TGCT cis rs28493229 0.708 rs78900506 chr19:41160096 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs6088590 0.687 rs6088582 chr20:33286798 G/A cg08999081 chr20:33150536 PIGU 0.27 5.01 0.41 1.81e-6 Coronary artery disease; TGCT cis rs9435341 0.965 rs1335055 chr1:107624563 A/G cg09367891 chr1:107599246 PRMT6 0.6 5.28 0.43 5.68e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs6912958 0.559 rs242287 chr6:88071825 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.42 5.32 0.43 4.64e-7 Monocyte percentage of white cells; TGCT cis rs231513 0.954 rs231501 chr17:41972303 C/T cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs2243480 1.000 rs9769882 chr7:65642925 T/C cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs2795502 0.873 rs1815716 chr10:43410200 G/A cg20628663 chr10:43360327 NA 0.36 5.47 0.44 2.42e-7 Blood protein levels; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg27535305 chr1:53392650 SCP2 -0.23 -4.52 -0.38 1.4e-5 Monocyte count; TGCT cis rs17764205 0.777 rs112570652 chr19:3255789 G/A cg18738857 chr19:3606974 TBXA2R -0.75 -4.65 -0.39 8.31e-6 Bipolar disorder and schizophrenia; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg12419862 chr22:24373484 LOC391322 -0.83 -9.36 -0.64 4.58e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs67311347 1.000 rs2276870 chr3:40499182 C/T cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6690583 0.623 rs1371143 chr1:85455532 C/T cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg18305652 chr10:134549665 INPP5A 0.34 5.75 0.46 6.43e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12220898 0.619 rs7911371 chr10:50485396 T/C cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs4665809 0.938 rs4665822 chr2:26312555 C/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs4372836 0.543 rs11686412 chr2:28992405 A/G cg09522027 chr2:28974177 PPP1CB -0.73 -7.07 -0.54 9.78e-11 Body mass index; TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg17457637 chr7:27170717 HOXA4 -0.46 -5.11 -0.42 1.19e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs2404602 0.532 rs744336 chr15:76674624 T/C cg22467129 chr15:76604101 ETFA -0.43 -4.71 -0.39 6.57e-6 Blood metabolite levels; TGCT cis rs644799 0.625 rs1255175 chr11:95471186 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.48 4.78 0.39 4.88e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1215050 0.791 rs2123100 chr4:98803747 T/C cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg00024416 chr22:24240387 NA -0.25 -4.9 -0.4 2.87e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6450176 1.000 rs4311394 chr5:53300662 A/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs853679 0.607 rs200489 chr6:27798257 T/C cg08798685 chr6:27730294 NA -0.36 -5.0 -0.41 1.91e-6 Depression; TGCT cis rs6089584 0.888 rs6061966 chr20:60607936 C/G cg13665807 chr20:60559372 TAF4 -0.46 -4.97 -0.41 2.2e-6 Body mass index; TGCT cis rs2180341 0.814 rs9401958 chr6:127736357 T/G cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs6752107 0.967 rs3816234 chr2:234185999 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.73 0.39 6.08e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg11965913 chr1:205819406 PM20D1 0.5 6.62 0.51 9.51e-10 Menarche (age at onset); TGCT cis rs34014631 1.000 rs79839205 chr10:103628939 T/C cg22630918 chr10:102748988 C10orf2 0.46 5.12 0.42 1.13e-6 Coronary artery calcification; TGCT cis rs4820539 1.000 rs5759596 chr22:23475750 G/A cg21100191 chr22:23484243 RTDR1 0.89 10.78 0.7 1.61e-19 Bone mineral density; TGCT cis rs11098499 0.954 rs3733520 chr4:120423480 C/G cg09307838 chr4:120376055 NA 0.7 6.81 0.52 3.69e-10 Corneal astigmatism; TGCT cis rs7809950 0.768 rs2701678 chr7:107283711 A/G cg23024343 chr7:107201750 COG5 0.44 6.2 0.49 7.8e-9 Coronary artery disease; TGCT cis rs2637266 0.653 rs846614 chr10:78549265 A/C cg18941641 chr10:78392320 NA 0.39 4.62 0.38 9.6e-6 Pulmonary function; TGCT cis rs7104764 1.000 rs7104764 chr11:229977 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.05 10.79 0.7 1.48e-19 Menarche (age at onset); TGCT cis rs1552244 1.000 rs61052895 chr3:10147516 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs9534288 0.830 rs1409435 chr13:46631660 G/A cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs8050907 0.744 rs10438587 chr16:4522160 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs1395 0.778 rs62128747 chr2:27412605 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.64 8.74 0.62 1.37e-14 Blood metabolite levels; TGCT cis rs12765878 0.967 rs10883940 chr10:105650598 G/A cg11005552 chr10:105648138 OBFC1 0.44 7.7 0.57 3.69e-12 Coronary artery disease; TGCT cis rs12478296 1.000 rs7603984 chr2:243047294 A/G cg06360820 chr2:242988706 NA -0.81 -5.3 -0.43 5.1e-7 Obesity-related traits; TGCT cis rs1799949 1.000 rs8176133 chr17:41257458 A/C cg23758822 chr17:41437982 NA 0.72 6.91 0.53 2.23e-10 Menopause (age at onset); TGCT cis rs10782582 0.586 rs5745383 chr1:76288590 G/C cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs9926296 0.535 rs36022917 chr16:89893238 A/G cg08627397 chr16:89984028 MC1R -0.3 -4.78 -0.39 4.93e-6 Vitiligo; TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg21226059 chr5:178986404 RUFY1 0.63 7.66 0.57 4.7e-12 Lung cancer; TGCT cis rs28595532 1.000 rs11098451 chr4:119717673 C/T cg21605333 chr4:119757512 SEC24D 1.18 7.55 0.56 8.01e-12 Cannabis dependence symptom count; TGCT cis rs6964587 1.000 rs61244255 chr7:91751662 C/T cg17063962 chr7:91808500 NA 0.89 9.51 0.65 1.95e-16 Breast cancer; TGCT cis rs1371867 0.846 rs1660353 chr8:101250907 C/T cg00191853 chr8:101177733 SPAG1 0.23 4.86 0.4 3.42e-6 Atrioventricular conduction; TGCT cis rs13108904 0.557 rs1250098 chr4:1238256 A/T cg20887711 chr4:1340912 KIAA1530 -0.58 -4.97 -0.41 2.17e-6 Obesity-related traits; TGCT cis rs2153535 0.580 rs915350 chr6:8443486 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.63 0.45 1.15e-7 Motion sickness; TGCT cis rs8179 0.645 rs66939011 chr7:92265798 T/C cg15732164 chr7:92237376 CDK6 -0.27 -4.66 -0.39 8.16e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg24846343 chr22:24311635 DDTL 0.23 5.85 0.46 4.19e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg03264133 chr6:25882463 NA 0.49 5.23 0.43 7e-7 Blood metabolite levels; TGCT cis rs12497850 0.931 rs9876848 chr3:48844059 G/A cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs4595586 0.545 rs4438082 chr12:39363870 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs12451471 0.559 rs34746710 chr17:78079224 G/A cg06718696 chr17:78121285 EIF4A3 0.71 5.89 0.47 3.42e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT trans rs208520 0.526 rs7775830 chr6:66755249 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.06 14.9 0.8 2.08e-29 Exhaled nitric oxide output; TGCT cis rs7552404 0.883 rs2185436 chr1:76203783 A/G cg22875332 chr1:76189707 ACADM 0.77 9.49 0.65 2.13e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs9517302 0.512 rs9517305 chr13:99097910 G/C cg22223119 chr13:99095684 FARP1 -0.53 -5.77 -0.46 6e-8 Obesity-related traits; TGCT cis rs9467773 0.967 rs7753565 chr6:26560012 A/G cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs3008870 0.701 rs2815367 chr1:67500762 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.2 0.59 2.61e-13 Lymphocyte percentage of white cells; TGCT cis rs514406 0.861 rs7513052 chr1:53241360 C/T cg22166914 chr1:53195759 ZYG11B -0.39 -6.57 -0.51 1.22e-9 Monocyte count; TGCT cis rs853679 0.527 rs707907 chr6:28291240 A/G cg18815343 chr6:28367644 ZSCAN12 -0.46 -4.79 -0.4 4.62e-6 Depression; TGCT cis rs10791097 0.694 rs2236711 chr11:130739284 G/A cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs17718580 0.536 rs2047150 chr14:51086387 A/G cg04730355 chr14:51134070 SAV1 1.21 9.01 0.63 3.15e-15 Cognitive performance; TGCT cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs2836974 0.653 rs8130556 chr21:40516872 C/T cg11644478 chr21:40555479 PSMG1 1.04 10.91 0.7 7.9e-20 Cognitive function; TGCT cis rs7666738 0.830 rs6532721 chr4:99048015 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs7772486 0.727 rs4896843 chr6:146063451 T/C cg23711669 chr6:146136114 FBXO30 -0.97 -11.02 -0.7 4.06e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs9372498 0.536 rs9489433 chr6:118867006 G/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT cis rs736408 0.609 rs13082960 chr3:52785168 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 5.99 0.47 2.06e-8 Bipolar disorder; TGCT cis rs4654899 0.802 rs76122612 chr1:21243059 C/T cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4988958 0.565 rs10206291 chr2:103038863 T/C cg03938978 chr2:103052716 IL18RAP 0.27 5.4 0.44 3.31e-7 Asthma (childhood onset); TGCT trans rs1814175 0.791 rs1722011 chr11:49899340 G/C cg03929089 chr4:120376271 NA -0.71 -8.06 -0.59 5.34e-13 Height; TGCT cis rs9527 0.590 rs2281877 chr10:104866062 C/T cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs6450176 1.000 rs3776715 chr5:53299095 T/C ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs35306767 0.903 rs12244253 chr10:889320 G/T cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs3947 0.865 rs1296028 chr8:11698747 A/G cg02840367 chr8:11660030 FDFT1 0.87 6.34 0.49 3.96e-9 Blood protein levels; TGCT cis rs6964587 1.000 rs12539231 chr7:91634963 G/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs28386778 0.863 rs58269663 chr17:61843130 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT trans rs1814175 0.745 rs7483456 chr11:49774613 C/T cg11707556 chr5:10655725 ANKRD33B -0.38 -7.76 -0.57 2.75e-12 Height; TGCT cis rs6591341 0.515 rs599301 chr11:68189945 G/C cg16797656 chr11:68205561 LRP5 0.29 5.12 0.42 1.16e-6 Lean body mass; TGCT cis rs13191362 1.000 rs68144677 chr6:163149024 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.35 0.64 4.74e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3020333 0.875 rs2941740 chr6:152009638 A/G cg22157087 chr6:152012887 ESR1 0.2 4.95 0.41 2.41e-6 Total body bone mineral density; TGCT cis rs67311347 0.544 rs7644181 chr3:40355665 A/G cg13683864 chr3:40499215 RPL14 0.81 7.55 0.56 8.09e-12 Renal cell carcinoma; TGCT cis rs7618915 0.501 rs12635140 chr3:52738165 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.55 5.19 0.42 8.2e-7 Bipolar disorder; TGCT cis rs2997447 0.761 rs61776616 chr1:26455812 C/T cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs523522 0.962 rs4766968 chr12:120947788 G/C cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs1008375 1.000 rs3846357 chr4:17635887 A/T cg16339924 chr4:17578868 LAP3 0.66 5.49 0.44 2.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1005277 0.602 rs2504142 chr10:38383793 C/T cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.13e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg12310025 chr6:25882481 NA 0.79 8.09 0.59 4.59e-13 Blood metabolite levels; TGCT cis rs903263 0.601 rs12746741 chr1:84539576 C/T cg09664975 chr1:84543551 PRKACB -0.51 -5.2 -0.42 7.96e-7 Breast cancer (male); TGCT cis rs1552244 0.935 rs11926481 chr3:10142102 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs9467711 0.516 rs523383 chr6:25869848 A/G cg12310025 chr6:25882481 NA -0.75 -5.07 -0.41 1.41e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4654899 0.965 rs10753513 chr1:21492168 T/C cg01072550 chr1:21505969 NA 0.51 8.23 0.59 2.18e-13 Superior frontal gyrus grey matter volume; TGCT cis rs2580764 0.540 rs10210840 chr2:55226009 G/A cg09592903 chr2:55203963 RTN4 -0.26 -5.67 -0.45 9.51e-8 Mean platelet volume; TGCT cis rs72949976 0.646 rs1441169 chr2:214033530 A/G cg08319019 chr2:214017104 IKZF2 0.87 8.54 0.61 4.02e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs11190604 1.000 rs2495754 chr10:102324812 C/T cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.18e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12477438 0.748 rs4851185 chr2:99666497 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs826838 0.838 rs11183646 chr12:38799846 A/T cg13010199 chr12:38710504 ALG10B 0.82 6.85 0.52 3e-10 Heart rate; TGCT cis rs1153858 1.000 rs4774577 chr15:45644685 A/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs896854 0.654 rs896846 chr8:95972453 G/A cg16049864 chr8:95962084 TP53INP1 -0.75 -10.47 -0.69 9.05e-19 Type 2 diabetes; TGCT cis rs9467773 1.000 rs9467782 chr6:26542773 G/A cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs1801251 1.000 rs10933412 chr2:233707226 G/C cg08000102 chr2:233561755 GIGYF2 -0.63 -6.46 -0.5 2.2e-9 Coronary artery disease; TGCT cis rs514406 0.861 rs1412706 chr1:53237721 G/A cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs1887596 0.705 rs653920 chr13:27228192 C/T cg01312412 chr13:27282625 NA 0.28 5.12 0.42 1.15e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs7647973 0.626 rs1352889 chr3:49652148 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs2486288 0.656 rs12911186 chr15:45551423 A/G cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs769267 0.965 rs735273 chr19:19385411 T/C cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs4780401 0.609 rs11639945 chr16:11824056 T/G cg01061890 chr16:11836724 TXNDC11 -0.57 -5.42 -0.44 3.05e-7 Rheumatoid arthritis; TGCT cis rs6089584 0.888 rs6061966 chr20:60607936 C/G cg16423285 chr20:60520624 NA -0.61 -6.51 -0.5 1.7e-9 Body mass index; TGCT cis rs3806843 0.576 rs246036 chr5:140331886 T/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg11644478 chr21:40555479 PSMG1 1.0 10.32 0.68 2.15e-18 Cognitive function; TGCT cis rs4906332 1.000 rs35366629 chr14:103903054 A/G cg26031613 chr14:104095156 KLC1 -0.53 -4.72 -0.39 6.2e-6 Coronary artery disease; TGCT cis rs12477438 0.765 rs6542846 chr2:99563654 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.55 -4.66 -0.39 8.14e-6 Chronic sinus infection; TGCT cis rs2692947 0.727 rs749459 chr2:96795714 G/A cg22654517 chr2:96458247 NA 0.22 4.87 0.4 3.37e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs909674 0.865 rs5757684 chr22:39851584 G/A cg24399712 chr22:39784796 NA -1.06 -11.24 -0.71 1.23e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7772486 0.790 rs7742333 chr6:146159029 A/G cg05347473 chr6:146136440 FBXO30 -0.48 -4.47 -0.37 1.71e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs17376456 0.877 rs12153501 chr5:93360866 T/G cg25358565 chr5:93447407 FAM172A 0.92 8.4 0.6 8.88e-14 Diabetic retinopathy; TGCT cis rs17767294 0.614 rs72849214 chr6:28187215 G/A cg08851530 chr6:28072375 NA 1.46 6.76 0.52 4.79e-10 Parkinson's disease; TGCT cis rs11264213 0.901 rs631202 chr1:36449099 G/C cg27506609 chr1:36549197 TEKT2 0.4 4.7 0.39 6.83e-6 Schizophrenia; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs35951881 chr4:98999474 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9677476 0.542 rs7595464 chr2:231967610 A/G cg27665808 chr2:232055229 NA 0.36 4.6 0.38 1.03e-5 Food antigen IgG levels; TGCT cis rs9443645 0.901 rs9352669 chr6:79584141 T/G cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs8180040 0.726 rs2385867 chr3:47059323 C/T cg27129171 chr3:47204927 SETD2 0.76 9.8 0.66 3.91e-17 Colorectal cancer; TGCT cis rs9905704 0.671 rs4337355 chr17:56950920 C/T cg12560992 chr17:57184187 TRIM37 0.57 4.9 0.4 2.87e-6 Testicular germ cell tumor; TGCT cis rs2404602 0.692 rs60658665 chr15:77042508 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs2243480 1.000 rs313824 chr7:65581207 C/T cg18252515 chr7:66147081 NA -1.24 -8.1 -0.59 4.35e-13 Diabetic kidney disease; TGCT cis rs6840360 0.642 rs2709816 chr4:152380269 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs16958440 0.867 rs78547658 chr18:44669852 C/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs7568458 0.870 rs1010 chr2:85808982 C/T cg02493740 chr2:85810744 VAMP5 0.27 4.77 0.39 4.99e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2204008 0.744 rs8186814 chr12:38335169 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs10197940 0.789 rs2444256 chr2:152280365 C/T cg06191203 chr2:152266755 RIF1 -0.74 -6.87 -0.52 2.79e-10 Lung cancer; TGCT cis rs514406 0.505 rs437954 chr1:53173321 C/G cg25767906 chr1:53392781 SCP2 -0.46 -5.09 -0.42 1.29e-6 Monocyte count; TGCT cis rs2479724 0.901 rs6458244 chr6:41790455 C/T cg08135965 chr6:41755394 TOMM6 -0.48 -4.79 -0.4 4.65e-6 Menarche (age at onset); TGCT cis rs1008375 1.000 rs55939327 chr4:17642937 T/A cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs59698941 0.550 rs11748737 chr5:132201070 C/T cg27099455 chr5:132201840 GDF9;UQCRQ 0.3 5.02 0.41 1.75e-6 Apolipoprotein A-IV levels; TGCT cis rs67460515 0.892 rs4856757 chr3:160999418 A/T cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT cis rs1862618 0.853 rs1833896 chr5:56097669 C/A cg24549020 chr5:56110836 MAP3K1 0.66 5.79 0.46 5.56e-8 Initial pursuit acceleration; TGCT cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg04267008 chr7:1944627 MAD1L1 -0.41 -5.46 -0.44 2.54e-7 Bipolar disorder and schizophrenia; TGCT trans rs10506458 1.000 rs1009539 chr12:63414655 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B 0.47 7.57 0.56 7.43e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs13188771 0.525 rs10477735 chr5:100918100 T/C cg18665594 chr5:101119420 NA 0.46 4.56 0.38 1.22e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs9929218 1.000 rs7200690 chr16:68778457 C/T cg01251360 chr16:68772225 CDH1 0.29 4.87 0.4 3.27e-6 Colorectal cancer; TGCT cis rs17767294 0.708 rs72847332 chr6:27773776 G/A cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs17711722 0.653 rs2460421 chr7:65491123 A/T cg18876405 chr7:65276391 NA -0.31 -4.93 -0.4 2.61e-6 Calcium levels; TGCT trans rs916888 0.697 rs199516 chr17:44856485 C/T cg10053473 chr17:62856997 LRRC37A3 0.46 6.8 0.52 3.99e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8177253 0.965 rs4854761 chr3:133498789 A/G cg08439880 chr3:133502540 NA 0.33 6.24 0.49 6.4e-9 Iron status biomarkers; TGCT cis rs78487399 0.710 rs6731998 chr2:43677273 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs62244186 0.608 rs2888390 chr3:44511405 G/A cg15687855 chr3:44754131 ZNF502 -0.44 -5.11 -0.42 1.18e-6 Depressive symptoms; TGCT cis rs9296092 0.538 rs80012910 chr6:33519542 G/A cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs75059851 0.756 rs11223658 chr11:133843216 G/A cg14047540 chr11:133829660 NA -0.58 -5.77 -0.46 6.07e-8 Schizophrenia; TGCT cis rs12701220 0.522 rs12334290 chr7:1054517 A/G cg03188948 chr7:1209495 NA 0.42 4.49 0.37 1.62e-5 Bronchopulmonary dysplasia; TGCT cis rs3774830 0.679 rs195121 chr4:5436104 C/T cg26943120 chr4:5472116 STK32B -0.25 -5.62 -0.45 1.18e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7611238 0.538 rs1353133 chr3:195160052 A/G cg27323046 chr3:195102265 ACAP2 0.33 4.44 0.37 1.96e-5 Body mass index; TGCT cis rs11190604 0.945 rs7091356 chr10:102292268 G/C cg23241863 chr10:102295624 HIF1AN 0.7 5.36 0.43 3.93e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg02725872 chr8:58115012 NA -0.41 -4.96 -0.41 2.28e-6 Developmental language disorder (linguistic errors); TGCT cis rs7552404 0.731 rs2029683 chr1:76341643 T/G cg22875332 chr1:76189707 ACADM -0.68 -7.11 -0.54 7.96e-11 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs931812 0.825 rs34235568 chr8:101895761 C/T cg20993868 chr7:22813445 NA 0.42 9.03 0.63 2.75e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs2299587 0.637 rs6586677 chr8:17890687 A/G cg04898035 chr8:17640624 MTUS1 -0.22 -4.75 -0.39 5.59e-6 Economic and political preferences; TGCT cis rs11648796 0.757 rs6600231 chr16:766485 A/G cg07343612 chr16:622815 PIGQ 0.34 5.02 0.41 1.75e-6 Height; TGCT cis rs10464366 0.544 rs4723824 chr7:39153698 T/C cg18850127 chr7:39170497 POU6F2 0.33 7.24 0.55 4.1e-11 IgG glycosylation; TGCT cis rs589249 0.853 rs1002656 chr1:37192741 C/T cg04012535 chr1:37176647 NA 0.32 4.87 0.4 3.28e-6 Neuroticism (multi-trait analysis);Schizophrenia; TGCT cis rs858239 0.601 rs6980224 chr7:23149137 C/T cg05602783 chr7:23145260 KLHL7 -0.63 -5.33 -0.43 4.55e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10883723 0.810 rs7072351 chr10:104265047 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2032447 0.867 rs9295683 chr6:26069495 C/T cg03517284 chr6:25882590 NA -0.63 -5.44 -0.44 2.73e-7 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg11905131 chr22:24372483 LOC391322 -1.0 -12.0 -0.73 1.73e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3820068 0.581 rs6429762 chr1:15945595 A/C cg05660106 chr1:15850417 CASP9 0.8 7.94 0.58 1.03e-12 Systolic blood pressure; TGCT cis rs5769765 0.913 rs2319462 chr22:50263370 C/T cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs6088580 0.634 rs6087587 chr20:33058628 G/T cg08999081 chr20:33150536 PIGU 0.29 5.66 0.45 9.97e-8 Glomerular filtration rate (creatinine); TGCT cis rs12497850 0.931 rs7647813 chr3:48833348 G/T cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs9399135 0.935 rs4445070 chr6:135309212 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.75 0.39 5.5e-6 Red blood cell count; TGCT cis rs4563143 0.675 rs55884228 chr19:29243897 G/T cg12667521 chr19:29218732 NA 0.54 5.72 0.46 7.65e-8 Methadone dose in opioid dependence; TGCT cis rs8077889 1.000 rs2342310 chr17:41866199 T/C cg26893861 chr17:41843967 DUSP3 1.08 13.1 0.76 3.73e-25 Triglycerides; TGCT cis rs2486288 0.656 rs7166580 chr15:45571209 C/G cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.32 -0.43 4.71e-7 Glomerular filtration rate; TGCT cis rs9527 0.641 rs34130454 chr10:104903638 A/G cg15744005 chr10:104629667 AS3MT -0.42 -4.86 -0.4 3.41e-6 Arsenic metabolism; TGCT cis rs6835098 1.000 rs4695826 chr4:174089426 T/G cg08422745 chr4:174089978 GALNT7 -0.94 -11.2 -0.71 1.48e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs7809950 1.000 rs2250414 chr7:107140987 T/G cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg26531700 chr6:26746687 NA -0.52 -4.94 -0.41 2.5e-6 Intelligence (multi-trait analysis); TGCT cis rs10782582 0.593 rs17647178 chr1:76210524 A/G cg22875332 chr1:76189707 ACADM -0.49 -5.39 -0.44 3.35e-7 Daytime sleep phenotypes; TGCT cis rs3087591 0.639 rs757378 chr17:29722619 A/T cg24425628 chr17:29625626 OMG;NF1 -0.39 -5.68 -0.45 9.08e-8 Hip circumference; TGCT cis rs13040088 1.000 rs12480870 chr20:61543606 A/C cg23096297 chr20:61557774 DIDO1 1.19 9.82 0.66 3.46e-17 Menopause (age at onset); TGCT cis rs17102423 0.692 rs762810 chr14:65544367 C/A cg11161011 chr14:65562177 MAX -0.55 -7.68 -0.57 4.15e-12 Obesity-related traits; TGCT cis rs6840360 0.607 rs2724565 chr4:152350305 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs12908161 1.000 rs35524990 chr15:85258203 T/C cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.95e-7 Schizophrenia; TGCT cis rs3812049 0.737 rs790154 chr5:127501235 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.57 5.18 0.42 8.76e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs11864453 0.612 rs12708925 chr16:72122706 A/T cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs7169223 0.615 rs11630027 chr15:79096983 C/A cg03762349 chr15:79060523 ADAMTS7 -0.26 -5.49 -0.44 2.18e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs9467711 0.606 rs9379864 chr6:26372584 G/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11648796 0.717 rs10682 chr16:767430 C/G cg00908189 chr16:619842 PIGQ 0.72 5.89 0.47 3.42e-8 Height; TGCT cis rs76878669 0.516 rs7104570 chr11:66159098 A/G cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.82e-9 Educational attainment (years of education); TGCT cis rs950776 0.642 rs7178007 chr15:78965254 G/A cg21242079 chr15:79101063 ADAMTS7 -0.31 -4.84 -0.4 3.74e-6 Sudden cardiac arrest; TGCT cis rs4455778 0.501 rs35433930 chr7:49059052 T/C cg26309511 chr7:48887640 NA 0.52 6.8 0.52 3.99e-10 Lung cancer in never smokers; TGCT cis rs42648 0.596 rs194513 chr7:89850170 G/T cg25739043 chr7:89950458 NA -0.49 -4.69 -0.39 7.02e-6 Homocysteine levels; TGCT cis rs4665809 0.549 rs7577896 chr2:26524493 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.07 6.31 0.49 4.6e-9 Gut microbiome composition (summer); TGCT cis rs3806843 1.000 rs4151680 chr5:140186657 A/G cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs3784262 0.669 rs12915989 chr15:58315736 C/A cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.27 -0.49 5.58e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9393777 0.546 rs9366673 chr6:26893329 C/G cg15659132 chr6:26577336 NA -0.68 -4.7 -0.39 6.94e-6 Intelligence (multi-trait analysis); TGCT cis rs1372520 0.684 rs2583979 chr4:90750588 A/T cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs7017914 0.967 rs59992214 chr8:71599545 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3820068 0.871 rs11585808 chr1:15805662 C/T cg05660106 chr1:15850417 CASP9 1.13 11.01 0.7 4.37e-20 Systolic blood pressure; TGCT cis rs7226408 1.000 rs72883550 chr18:34361547 G/A cg06757138 chr18:34340585 FHOD3 0.28 4.76 0.39 5.23e-6 Obesity-related traits; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg00024416 chr22:24240387 NA 0.35 5.99 0.47 2.14e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9556958 0.708 rs9513435 chr13:99160334 C/G cg15168958 chr13:99100528 FARP1 0.21 4.7 0.39 6.91e-6 Educational attainment (years of education); TGCT cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7937682 0.632 rs7112886 chr11:111743232 T/C cg09085632 chr11:111637200 PPP2R1B 0.81 7.14 0.54 6.97e-11 Primary sclerosing cholangitis; TGCT cis rs2964802 0.505 rs6876703 chr5:10831629 G/A cg14521931 chr5:10832172 NA -0.27 -4.59 -0.38 1.06e-5 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs2721195 0.874 rs2721173 chr8:145744429 C/T cg15320075 chr8:145703422 NA 0.7 7.24 0.55 4.07e-11 Age at first birth; TGCT cis rs7618915 0.508 rs7628578 chr3:52628321 A/T cg07507251 chr3:52567010 NT5DC2 0.48 6.79 0.52 4.12e-10 Bipolar disorder; TGCT trans rs7618501 0.519 rs3774750 chr3:50208406 C/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.79 -8.22 -0.59 2.36e-13 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs1372520 0.873 rs983361 chr4:90761944 T/G cg20003494 chr4:90757398 SNCA -0.67 -5.69 -0.46 8.62e-8 Neuroticism; TGCT cis rs7772486 0.790 rs2249147 chr6:146184999 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.88 0.4 3.26e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2282802 0.635 rs397463 chr5:139584275 C/G cg01081189 chr5:139537190 NA -0.28 -5.07 -0.41 1.43e-6 Intelligence (multi-trait analysis); TGCT cis rs7914558 0.966 rs1890185 chr10:104748718 A/G cg04362960 chr10:104952993 NT5C2 0.6 5.42 0.44 2.99e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs8016982 0.674 rs2288499 chr14:81660997 C/T cg01989461 chr14:81687754 GTF2A1 0.78 7.94 0.58 1.06e-12 Schizophrenia; TGCT cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg10263370 chr3:44754102 ZNF502 -0.4 -4.8 -0.4 4.4e-6 Depressive symptoms; TGCT cis rs208520 0.909 rs62414639 chr6:67023706 G/A cg07460842 chr6:66804631 NA 0.69 5.72 0.46 7.53e-8 Exhaled nitric oxide output; TGCT cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg20203395 chr5:56204925 C5orf35 0.79 6.24 0.49 6.41e-9 Initial pursuit acceleration; TGCT cis rs2153535 0.541 rs9328471 chr6:8468842 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg11905131 chr22:24372483 LOC391322 -0.82 -8.0 -0.58 7.68e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4665809 1.000 rs6546727 chr2:26275282 C/T cg27170947 chr2:26402098 FAM59B -0.4 -4.55 -0.38 1.25e-5 Gut microbiome composition (summer); TGCT cis rs6693567 0.545 rs6664703 chr1:150459087 G/C cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Migraine; TGCT cis rs9527 0.590 rs2274339 chr10:104860053 T/A cg15744005 chr10:104629667 AS3MT -0.41 -4.8 -0.4 4.46e-6 Arsenic metabolism; TGCT cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.89 9.34 0.64 5.06e-16 Platelet count; TGCT trans rs10435719 0.867 rs6999030 chr8:11795308 G/A cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs6565180 0.926 rs4788409 chr16:30393771 G/A cg17640201 chr16:30407289 ZNF48 0.96 9.04 0.63 2.57e-15 Tonsillectomy; TGCT cis rs7246657 0.722 rs16958861 chr19:38124179 G/A cg18154014 chr19:37997991 ZNF793 0.68 4.57 0.38 1.18e-5 Coronary artery calcification; TGCT cis rs1865760 0.865 rs6929805 chr6:25950834 T/A cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs9467773 1.000 rs12526680 chr6:26550954 A/G cg05738196 chr6:26577821 NA 0.91 13.11 0.76 3.53e-25 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs13118159 0.509 rs10023473 chr4:1375285 C/T cg19318889 chr4:1322082 MAEA 0.28 6.63 0.51 9.18e-10 Longevity; TGCT cis rs11190604 1.000 rs11816840 chr10:102309220 G/C cg16342193 chr10:102329863 NA -0.39 -4.95 -0.41 2.36e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4730250 0.707 rs257381 chr7:106803963 T/C cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.9e-8 Osteoarthritis; TGCT cis rs796364 0.616 rs769956 chr2:200693720 C/T cg17644776 chr2:200775616 C2orf69 -0.34 -4.84 -0.4 3.76e-6 Schizophrenia; TGCT cis rs7973719 0.868 rs7315553 chr12:7353838 A/C cg07052231 chr12:7363540 PEX5 0.36 5.6 0.45 1.34e-7 IgG glycosylation; TGCT cis rs9910055 0.607 rs13726 chr17:42239561 C/T cg13607699 chr17:42295918 UBTF 0.79 7.23 0.54 4.29e-11 Total body bone mineral density; TGCT trans rs9329221 0.617 rs483916 chr8:9793601 A/C cg06636001 chr8:8085503 FLJ10661 -0.81 -8.56 -0.61 3.74e-14 Neuroticism; TGCT cis rs9811920 0.809 rs766778 chr3:99751480 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.02 0.41 1.79e-6 Axial length; TGCT cis rs7954584 0.567 rs10840632 chr12:122375460 C/T cg21016266 chr12:122356598 WDR66 0.52 6.4 0.5 2.83e-9 Mean corpuscular volume; TGCT cis rs7954584 0.531 rs10840631 chr12:122373729 C/T cg13699009 chr12:122356056 WDR66 0.29 5.72 0.46 7.44e-8 Mean corpuscular volume; TGCT cis rs12142240 0.698 rs12385695 chr1:46819021 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6088590 0.648 rs6059991 chr20:33280836 C/T cg08999081 chr20:33150536 PIGU 0.27 5.01 0.41 1.81e-6 Coronary artery disease; TGCT cis rs10088262 0.591 rs13270541 chr8:124794849 G/A cg02993010 chr8:124780839 FAM91A1 -0.63 -5.13 -0.42 1.08e-6 Pancreatic cancer; TGCT cis rs17253792 0.822 rs75351812 chr14:56082192 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg02503808 chr4:7069936 GRPEL1 -0.94 -9.06 -0.63 2.36e-15 Monocyte percentage of white cells; TGCT cis rs669446 0.558 rs594293 chr1:44109199 A/G cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs7840202 0.506 rs7827839 chr8:103353730 C/T cg22150661 chr8:104032860 ATP6V1C1 0.3 4.64 0.38 8.9e-6 Rate of cognitive decline in mild cognitive impairment (time interaction);Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs6940638 0.615 rs9393801 chr6:27242681 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.43 -4.5 -0.37 1.52e-5 Intelligence (multi-trait analysis); TGCT cis rs4595586 0.545 rs1303887 chr12:39366523 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs709400 0.633 rs8013101 chr14:103951772 G/C cg26031613 chr14:104095156 KLC1 0.84 9.5 0.65 2.08e-16 Body mass index; TGCT trans rs916888 0.610 rs199436 chr17:44789285 C/T cg01341218 chr17:43662625 NA -0.82 -7.6 -0.56 6.45e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs11088226 0.681 rs2833906 chr21:33945521 G/T cg09050820 chr6:167586206 TCP10L2 0.82 7.4 0.55 1.8e-11 Gastritis; TGCT cis rs2239547 0.522 rs2581805 chr3:52979050 T/C cg10802521 chr3:52805072 NEK4 0.64 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs6912958 0.630 rs9450726 chr6:88236728 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.51 -4.64 -0.38 8.6e-6 Monocyte percentage of white cells; TGCT cis rs7681440 0.626 rs1372510 chr4:90817259 G/A cg10208370 chr4:90758469 SNCA -0.57 -5.41 -0.44 3.05e-7 Dementia with Lewy bodies; TGCT cis rs12257961 0.549 rs7900826 chr10:15382981 C/A cg10616319 chr10:15468812 NA 0.25 4.66 0.39 8.15e-6 Selective IgA deficiency; TGCT cis rs1865760 0.566 rs2858993 chr6:26087856 T/A cg17042849 chr6:26104293 HIST1H4C -0.65 -5.52 -0.44 1.89e-7 Height; TGCT cis rs2836950 0.565 rs7276046 chr21:40581293 T/C cg06238570 chr21:40685208 BRWD1 -0.62 -6.42 -0.5 2.57e-9 Menarche (age at onset); TGCT cis rs9788682 1.000 rs35212593 chr15:78831826 G/A cg06917634 chr15:78832804 PSMA4 -0.7 -4.86 -0.4 3.47e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs1218582 0.741 rs11264283 chr1:154869552 A/G cg09359103 chr1:154839909 KCNN3 -0.66 -12.08 -0.74 1.09e-22 Prostate cancer; TGCT cis rs4700695 0.841 rs706681 chr5:65317913 G/T cg21114390 chr5:65439923 SFRS12 0.62 4.62 0.38 9.51e-6 Facial morphology (factor 19); TGCT cis rs35306767 0.903 rs17159970 chr10:935601 T/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs4455778 0.600 rs4255086 chr7:49109798 T/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs494003 1.000 rs11227288 chr11:65516588 G/C cg04293602 chr11:65553660 OVOL1 0.36 4.62 0.38 9.28e-6 Systemic lupus erythematosus; TGCT cis rs200810 0.694 rs59740076 chr6:97996564 T/G cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.65 -4.45 -0.37 1.91e-5 Body mass index; TGCT cis rs10992471 0.603 rs2094281 chr9:95290654 C/G cg14631576 chr9:95140430 CENPP 0.3 4.8 0.4 4.42e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3770081 1.000 rs78646493 chr2:86283195 A/C cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs2243480 1.000 rs58669269 chr7:65951953 T/C cg20637647 chr7:64974828 NA 0.91 5.33 0.43 4.55e-7 Diabetic kidney disease; TGCT cis rs13102973 0.674 rs11730572 chr4:135885397 C/T cg14419869 chr4:135874104 NA 0.26 4.55 0.38 1.28e-5 Subjective well-being; TGCT cis rs8013055 0.846 rs11624007 chr14:105992183 A/C cg19700328 chr14:106028568 NA -0.53 -5.79 -0.46 5.32e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9682041 0.668 rs6784631 chr3:170100476 T/C cg11886554 chr3:170076028 SKIL 0.88 6.41 0.5 2.82e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7255374 0.566 rs11666982 chr19:41531368 T/G cg20630647 chr19:41531805 NA 0.38 6.57 0.51 1.23e-9 DDT metabolite (p,p'-DDE levels); TGCT cis rs13191362 0.935 rs4273664 chr6:162955494 T/G cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.17e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs10986311 0.706 rs7854989 chr9:127133584 T/C cg14243010 chr9:127117328 LOC100129034;PSMB7 0.18 4.63 0.38 9.02e-6 Vitiligo; TGCT cis rs9517320 0.534 rs912330 chr13:99131294 C/T cg07423050 chr13:99094983 FARP1 -0.26 -4.79 -0.4 4.58e-6 Longevity; TGCT cis rs9318086 0.753 rs9553094 chr13:24474613 A/G cg16267784 chr13:24449046 MIPEP 0.22 4.46 0.37 1.79e-5 Myopia (pathological); TGCT cis rs909674 0.524 rs5757670 chr22:39829736 G/A cg05872129 chr22:39784769 NA -0.97 -10.56 -0.69 5.57e-19 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6430585 0.528 rs309152 chr2:136657252 C/T cg07169764 chr2:136633963 MCM6 -1.11 -10.8 -0.7 1.46e-19 Corneal structure; TGCT cis rs7666738 0.830 rs2865978 chr4:99017946 G/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7635838 0.617 rs346071 chr3:11305584 A/T cg00170343 chr3:11313890 ATG7 -0.62 -6.13 -0.48 1.07e-8 HDL cholesterol; TGCT cis rs2617583 0.530 rs10060889 chr5:1456803 A/G cg13982541 chr5:1466431 LPCAT1 0.19 4.55 0.38 1.28e-5 Breast cancer; TGCT cis rs2594989 0.779 rs111827101 chr3:11587736 T/C cg00170343 chr3:11313890 ATG7 -0.68 -5.1 -0.42 1.26e-6 Circulating chemerin levels; TGCT cis rs10501293 0.746 rs7110938 chr11:43007392 G/A cg03447554 chr11:43094025 NA 0.43 6.19 0.49 8.04e-9 Cognitive performance; TGCT cis rs2797160 1.000 rs6933302 chr6:126016951 T/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg18305652 chr10:134549665 INPP5A 0.34 5.51 0.44 2.02e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6429082 0.518 rs1812350 chr1:235659920 C/A cg26050004 chr1:235667680 B3GALNT2 0.83 8.86 0.62 7.1e-15 Adiposity; TGCT cis rs514406 0.861 rs12038438 chr1:53230581 A/T cg08859206 chr1:53392774 SCP2 0.39 5.98 0.47 2.23e-8 Monocyte count; TGCT cis rs769267 0.965 rs6511026 chr19:19391402 C/T cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs4699052 0.662 rs2866645 chr4:104239201 A/G cg16532752 chr4:104119610 CENPE -0.58 -5.86 -0.47 3.96e-8 Testicular germ cell tumor; TGCT cis rs7552404 0.627 rs12127049 chr1:76353248 G/A cg03433033 chr1:76189801 ACADM 0.76 7.55 0.56 8.35e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1524927 0.933 rs12704874 chr7:96340744 A/G cg03808172 chr7:96339361 SHFM1 0.49 5.06 0.41 1.45e-6 Total body bone mineral density; TGCT cis rs28785552 0.931 rs10424385 chr19:53239133 C/G cg22067481 chr19:53234126 ZNF611 -0.49 -7.05 -0.53 1.1e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs644148 0.836 rs2686774 chr19:44999827 T/C cg15540054 chr19:45004280 ZNF180 -0.65 -5.33 -0.43 4.48e-7 Personality dimensions; TGCT cis rs9910055 0.659 rs7216294 chr17:42251095 T/C cg13607699 chr17:42295918 UBTF 0.59 5.31 0.43 4.88e-7 Total body bone mineral density; TGCT cis rs6669384 0.774 rs7550821 chr1:208029947 C/T cg22525895 chr1:207977042 MIR29B2 -0.4 -5.72 -0.46 7.44e-8 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs2243480 0.831 rs7806717 chr7:65393174 A/G cg20637647 chr7:64974828 NA -0.89 -4.99 -0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs12220898 0.749 rs10735220 chr10:50473635 A/G cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.85e-5 Inflammatory biomarkers; TGCT cis rs1008375 1.000 rs4235388 chr4:17682030 G/A cg16339924 chr4:17578868 LAP3 0.56 4.82 0.4 4.1e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10754283 0.967 rs10737707 chr1:90119304 A/G cg03145924 chr1:90228473 NA -0.4 -4.52 -0.38 1.4e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs25422 0.938 rs7356858 chr6:118765814 G/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Renal cell carcinoma; TGCT cis rs7208859 0.673 rs55904046 chr17:29215391 G/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs346785 0.692 rs6501882 chr17:74289875 C/T cg09812376 chr17:74270190 QRICH2 -0.36 -5.33 -0.43 4.43e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg11494091 chr17:61959527 GH2 0.6 14.48 0.79 1.94e-28 Prudent dietary pattern; TGCT cis rs7267979 0.868 rs6138546 chr20:25216534 G/A cg03522245 chr20:25566470 NINL 0.6 6.57 0.51 1.22e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg20203395 chr5:56204925 C5orf35 0.59 5.12 0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs9457247 1.000 rs397713 chr6:167386714 G/A cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs7666738 0.649 rs28865589 chr4:98954279 C/A cg18180107 chr4:99064573 C4orf37 0.56 5.05 0.41 1.53e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs909685 1.000 rs2069235 chr22:39747780 C/T cg17798944 chr22:39715225 SNORD43;RPL3 0.63 6.08 0.48 1.36e-8 Rheumatoid arthritis; TGCT cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg12310025 chr6:25882481 NA -0.55 -5.84 -0.46 4.23e-8 Height; TGCT cis rs3027009 0.881 rs61828178 chr1:159159041 G/T cg27303699 chr1:158224869 CD1A -0.4 -4.72 -0.39 6.34e-6 Lean body mass and age at menarche (combined); TGCT cis rs7618915 0.571 rs7623199 chr3:52605974 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs2066819 1.000 rs773664 chr12:56702176 C/T cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT cis rs13256369 0.851 rs11249889 chr8:8564992 G/T cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs6582630 0.555 rs11181657 chr12:38381858 T/C cg26384229 chr12:38710491 ALG10B -0.81 -7.13 -0.54 7.23e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs6088580 0.634 rs4911418 chr20:32994257 G/A cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs514406 0.763 rs6685599 chr1:53213172 G/A cg22166914 chr1:53195759 ZYG11B -0.41 -7.06 -0.54 1.05e-10 Monocyte count; TGCT cis rs10504229 0.728 rs72650855 chr8:58152570 A/G cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs12422267 0.609 rs10128884 chr12:132621624 C/T cg09764611 chr12:132620959 NA -0.32 -4.9 -0.4 2.94e-6 Plasma amyloid beta peptide concentrations (ABx-40); TGCT cis rs80033912 0.626 rs71324982 chr3:49669948 G/A cg07636037 chr3:49044803 WDR6 0.62 5.04 0.41 1.57e-6 Intelligence (multi-trait analysis); TGCT cis rs6424115 0.644 rs2267960 chr1:24068544 T/C cg15997130 chr1:24165203 NA 0.62 6.36 0.5 3.5e-9 Immature fraction of reticulocytes; TGCT cis rs1953600 1.000 rs1953600 chr10:81911725 A/G cg04850286 chr10:81895943 PLAC9 0.39 4.54 0.38 1.3e-5 Sarcoidosis; TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg10150615 chr22:24372951 LOC391322 -0.97 -12.64 -0.75 4.94e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836974 0.583 rs9636957 chr21:40705847 G/A cg11644478 chr21:40555479 PSMG1 -0.53 -4.55 -0.38 1.28e-5 Cognitive function; TGCT cis rs8067545 1.000 rs8067545 chr17:19912710 T/C cg13482628 chr17:19912719 NA 0.55 4.83 0.4 3.98e-6 Schizophrenia; TGCT cis rs921968 0.608 rs7598056 chr2:219352511 A/C cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs61935443 0.666 rs73218073 chr12:95314346 A/G cg21533806 chr12:95267307 NA 0.57 4.75 0.39 5.43e-6 Schizophrenia; TGCT cis rs2730245 0.527 rs712197 chr7:158660846 C/G cg11984989 chr7:158649758 WDR60 1.01 7.8 0.57 2.2e-12 Height; TGCT cis rs6840360 0.642 rs2709828 chr4:152355268 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.765 rs6542846 chr2:99563654 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.55 -0.38 1.25e-5 Chronic sinus infection; TGCT cis rs12510870 0.674 rs1528918 chr4:74452590 C/T cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs7246657 0.722 rs3095726 chr19:38229824 T/C cg18154014 chr19:37997991 ZNF793 -0.71 -4.88 -0.4 3.24e-6 Coronary artery calcification; TGCT cis rs10504229 0.683 rs16921831 chr8:58111142 G/A cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg13397359 chr6:42928475 GNMT 0.72 6.48 0.5 1.93e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs172166 0.694 rs9295760 chr6:28147385 G/A cg10876282 chr6:28092338 ZSCAN16 0.49 4.53 0.38 1.37e-5 Cardiac Troponin-T levels; TGCT cis rs2932538 0.961 rs3795820 chr1:113163042 C/A cg22162597 chr1:113214053 CAPZA1 -0.28 -5.85 -0.47 4.01e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7618915 0.571 rs6778844 chr3:52596398 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.63 -6.34 -0.5 3.79e-9 Bipolar disorder; TGCT cis rs2836974 0.897 rs1984022 chr21:40596085 G/A cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.3e-9 Cognitive function; TGCT cis rs10791097 0.694 rs7125622 chr11:130743388 T/C cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2455799 0.634 rs62243671 chr3:15921098 C/T cg16303742 chr3:15540471 COLQ -0.24 -4.61 -0.38 9.69e-6 Mean platelet volume; TGCT cis rs7666738 0.830 rs11721726 chr4:98996314 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs5750830 0.595 rs4821892 chr22:39795683 G/C cg02038168 chr22:39784481 NA -0.77 -6.41 -0.5 2.78e-9 Intelligence (multi-trait analysis); TGCT cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg03452623 chr4:187889614 NA -0.37 -5.7 -0.46 8.2e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg12034118 chr1:209979487 IRF6 0.58 4.48 0.37 1.66e-5 Cleft lip with or without cleft palate; TGCT cis rs2204008 0.582 rs11179135 chr12:38204689 A/C cg26384229 chr12:38710491 ALG10B 0.78 6.56 0.51 1.32e-9 Bladder cancer; TGCT cis rs2730245 1.000 rs2657365 chr7:158722753 A/T cg11984989 chr7:158649758 WDR60 -0.94 -8.49 -0.61 5.3e-14 Height; TGCT cis rs926938 0.812 rs11102832 chr1:115244253 G/C cg12756093 chr1:115239321 AMPD1 -0.43 -5.97 -0.47 2.28e-8 Autism; TGCT cis rs2243480 1.000 rs34577383 chr7:65385726 C/T cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs826838 1.000 rs1719830 chr12:39096992 T/G cg26384229 chr12:38710491 ALG10B -0.85 -8.1 -0.59 4.39e-13 Heart rate; TGCT cis rs3026101 0.624 rs1806261 chr17:5317008 A/C cg25236894 chr17:5323110 RPAIN;NUP88 0.45 4.47 0.37 1.73e-5 Body mass index; TGCT cis rs6598955 0.670 rs12733645 chr1:26540356 G/T cg04990556 chr1:26633338 UBXN11 -0.89 -11.24 -0.71 1.2e-20 Obesity-related traits; TGCT cis rs1153858 1.000 rs1890565 chr15:45663299 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7267979 1.000 rs2482919 chr20:25299756 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28595532 1.000 rs17323012 chr4:119605671 A/G cg11846333 chr4:119757529 SEC24D 0.95 4.68 0.39 7.49e-6 Cannabis dependence symptom count; TGCT cis rs9952991 0.943 rs9952753 chr18:12780463 A/C cg24737193 chr18:12778029 NA 0.53 5.93 0.47 2.8e-8 Inflammatory skin disease; TGCT cis rs4851266 0.966 rs13018640 chr2:100821545 T/C cg07810366 chr2:100720526 AFF3 -0.41 -5.82 -0.46 4.72e-8 Educational attainment; TGCT cis rs2050392 0.590 rs694346 chr10:30711929 C/T cg13289132 chr10:30722225 MAP3K8 -0.46 -5.69 -0.45 8.77e-8 Inflammatory bowel disease; TGCT cis rs2880765 0.835 rs4360875 chr15:86040394 A/G cg13263323 chr15:86062960 AKAP13 -0.23 -4.83 -0.4 4e-6 Coronary artery disease; TGCT cis rs10197940 0.550 rs77233070 chr2:152416477 G/A cg06191203 chr2:152266755 RIF1 -0.67 -5.99 -0.47 2.09e-8 Lung cancer; TGCT cis rs2073300 1.000 rs79255223 chr20:23443559 G/T cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs9486715 0.867 rs926277 chr6:96868837 T/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs1670533 1.000 rs4690212 chr4:1054898 T/C cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs3780378 0.870 rs2149556 chr9:5059440 C/T cg02405213 chr9:5042618 JAK2 -0.64 -8.93 -0.63 4.87e-15 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT trans rs3780486 0.846 rs10116966 chr9:33122370 T/A cg20290983 chr6:43655470 MRPS18A 1.21 15.13 0.81 5.99e-30 IgG glycosylation; TGCT cis rs2012796 0.743 rs12435764 chr14:81836866 A/C cg02996355 chr14:81879375 NA 0.58 5.75 0.46 6.46e-8 Night sleep phenotypes; TGCT cis rs6542838 0.641 rs10192266 chr2:99521837 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.27 -0.43 5.77e-7 Fear of minor pain; TGCT cis rs2115536 1.000 rs11637477 chr15:80193295 C/T cg00225070 chr15:80189496 MTHFS 0.62 5.58 0.45 1.42e-7 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9790314 0.934 rs462413 chr3:161101587 T/C cg03342759 chr3:160939853 NMD3 -0.44 -4.57 -0.38 1.15e-5 Morning vs. evening chronotype; TGCT cis rs9914544 1.000 rs67411574 chr17:18797337 A/G cg26378065 chr17:18585709 ZNF286B 0.52 4.73 0.39 5.94e-6 Educational attainment (years of education); TGCT cis rs1552244 0.515 rs67626468 chr3:10161518 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 4.93 0.41 2.53e-6 Alzheimer's disease; TGCT cis rs617219 0.671 rs2591392 chr5:78546293 G/A cg23987322 chr5:78407566 BHMT 0.35 4.56 0.38 1.23e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1218582 0.741 rs4339857 chr1:154888962 A/G cg24250549 chr1:154909240 PMVK 0.63 6.25 0.49 6.03e-9 Prostate cancer; TGCT cis rs79149102 0.579 rs6495138 chr15:75304692 A/G cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg20203395 chr5:56204925 C5orf35 -0.57 -4.84 -0.4 3.85e-6 Initial pursuit acceleration; TGCT cis rs2204008 0.805 rs11179579 chr12:38213957 A/C cg26384229 chr12:38710491 ALG10B 0.84 7.45 0.56 1.37e-11 Bladder cancer; TGCT cis rs6725041 0.792 rs1533768 chr2:213089875 T/A cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs1372520 0.577 rs2737021 chr4:90739992 T/A cg14346243 chr4:90757452 SNCA -0.68 -5.57 -0.45 1.48e-7 Neuroticism; TGCT cis rs7681440 1.000 rs1471483 chr4:90754292 A/G cg20003494 chr4:90757398 SNCA -0.55 -4.95 -0.41 2.35e-6 Dementia with Lewy bodies; TGCT cis rs9527 0.545 rs7894588 chr10:104756030 A/T cg15744005 chr10:104629667 AS3MT -0.49 -5.32 -0.43 4.62e-7 Arsenic metabolism; TGCT cis rs12477438 0.501 rs11683188 chr2:99724512 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs514406 0.861 rs7526275 chr1:53245849 C/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs9457247 1.000 rs398278 chr6:167388169 A/G cg25258033 chr6:167368657 RNASET2 0.2 4.84 0.4 3.85e-6 Crohn's disease; TGCT cis rs6988636 1.000 rs10096350 chr8:124184470 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs5769707 0.967 rs9616333 chr22:50050847 G/A cg05373962 chr22:49881684 NA -0.32 -6.65 -0.51 8.38e-10 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1005277 0.522 rs7090858 chr10:38003670 A/C cg25427524 chr10:38739819 LOC399744 0.36 7.15 0.54 6.46e-11 Extrinsic epigenetic age acceleration; TGCT cis rs9929218 0.906 rs34565494 chr16:68741769 C/T cg01251360 chr16:68772225 CDH1 0.29 4.77 0.39 5.03e-6 Colorectal cancer; TGCT cis rs6500602 0.647 rs3747600 chr16:4586222 A/G cg08645402 chr16:4508243 NA 0.18 5.05 0.41 1.54e-6 Schizophrenia; TGCT cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.82e-6 Obesity-related traits; TGCT cis rs5769707 0.967 rs17182154 chr22:49990470 A/G cg10356904 chr22:49881777 NA -0.23 -4.77 -0.39 5.14e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9372253 1.000 rs9374170 chr6:110712991 A/G cg00083206 chr6:110721305 DDO -0.4 -6.07 -0.48 1.44e-8 Platelet distribution width; TGCT cis rs2067615 0.542 rs4964184 chr12:107070425 A/T cg15890332 chr12:107067104 RFX4 0.29 5.73 0.46 7.31e-8 Heart rate; TGCT cis rs1670533 1.000 rs11725984 chr4:1087338 C/T cg27284194 chr4:1044797 NA 0.68 5.95 0.47 2.59e-8 Recombination rate (females); TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.13 0.82 3.12e-32 Prudent dietary pattern; TGCT cis rs9388451 0.874 rs3734634 chr6:126111800 G/A cg10911889 chr6:126070802 HEY2 0.48 4.97 0.41 2.18e-6 Brugada syndrome; TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg14893161 chr1:205819251 PM20D1 0.52 6.83 0.52 3.3e-10 Menarche (age at onset); TGCT cis rs7727544 0.684 rs270602 chr5:131656700 T/C cg24060327 chr5:131705240 SLC22A5 -0.57 -6.19 -0.49 8.19e-9 Blood metabolite levels; TGCT cis rs7100689 0.646 rs1934693 chr10:82125650 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg24675658 chr1:53192096 ZYG11B -0.7 -8.15 -0.59 3.44e-13 Monocyte count; TGCT cis rs12478296 0.685 rs67829386 chr2:242992276 T/A cg06360820 chr2:242988706 NA -0.61 -4.68 -0.39 7.26e-6 Obesity-related traits; TGCT cis rs17376456 0.877 rs10476526 chr5:93461916 G/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs9952991 0.941 rs2542151 chr18:12779947 G/T cg09945482 chr18:12777974 NA 0.5 4.82 0.4 4.07e-6 Inflammatory skin disease; TGCT cis rs7224685 0.569 rs7213885 chr17:4018489 T/A cg09580393 chr17:4869866 SPAG7 -0.38 -4.46 -0.37 1.82e-5 Type 2 diabetes; TGCT cis rs35160687 0.842 rs10200619 chr2:86548848 T/C cg03171300 chr2:86307199 POLR1A -0.27 -4.81 -0.4 4.34e-6 Night sleep phenotypes; TGCT cis rs17767294 0.522 rs78037434 chr6:27848898 A/T cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs3885907 0.542 rs4147063 chr13:31319954 A/G cg22282089 chr13:30686841 NA -0.22 -4.56 -0.38 1.21e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT cis rs9916302 0.904 rs602688 chr17:37439496 C/T cg15445000 chr17:37608096 MED1 0.31 4.57 0.38 1.16e-5 Glomerular filtration rate (creatinine); TGCT cis rs12681288 0.823 rs12681230 chr8:994422 G/A cg04851639 chr8:1020857 NA -0.34 -5.75 -0.46 6.43e-8 Schizophrenia; TGCT cis rs6840360 0.642 rs7684462 chr4:152348422 T/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs11711311 1.000 rs11711311 chr3:113430599 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs60871478 0.541 rs56964970 chr7:910791 G/C cg00475322 chr7:917719 C7orf20 0.52 5.04 0.41 1.58e-6 Cerebrospinal P-tau181p levels; TGCT cis rs8062405 0.824 rs4788083 chr16:28545449 A/G cg09754948 chr16:28834200 ATXN2L 0.61 4.82 0.4 4.12e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs34245846 0.769 rs12084791 chr1:154824973 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.74 5.93 0.47 2.84e-8 Atrial fibrillation; TGCT cis rs2456568 0.900 rs2511399 chr11:93682156 C/T cg16099599 chr11:93583650 C11orf90 0.39 4.81 0.4 4.35e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7772486 0.754 rs12199362 chr6:146118225 A/G cg13319975 chr6:146136371 FBXO30 -0.58 -5.24 -0.43 6.75e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6088590 0.561 rs764597 chr20:33161225 C/T cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs61884328 0.657 rs12578030 chr11:47234601 A/G cg13308137 chr11:47528955 CUGBP1 0.38 4.56 0.38 1.23e-5 Total body bone mineral density (age over 60); TGCT cis rs7666738 0.830 rs13125537 chr4:98978428 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.584 rs7548832 chr1:53193576 A/T cg16325326 chr1:53192061 ZYG11B 0.89 12.96 0.76 8.21e-25 Monocyte count; TGCT cis rs7949030 0.622 rs34894392 chr11:62374821 A/G cg13298116 chr11:62369859 EML3;MTA2 0.63 9.23 0.64 9.4e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4819052 0.851 rs8131143 chr21:46671646 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.84 -7.63 -0.57 5.48e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7769051 0.711 rs6569847 chr6:133083187 C/A cg22852734 chr6:133119734 C6orf192 1.17 6.33 0.49 4.15e-9 Type 2 diabetes nephropathy; TGCT cis rs13191362 1.000 rs35103567 chr6:163183400 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.76 0.52 4.71e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2663905 1.000 rs2663905 chr15:81359137 G/A cg18837035 chr15:81426597 C15orf26 -0.58 -5.24 -0.43 6.56e-7 QT interval (drug interaction); TGCT cis rs7582180 0.652 rs4851311 chr2:100980398 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.68 0.39 7.26e-6 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.605 rs1800287 chr16:89858525 C/G cg21285383 chr16:89894308 SPIRE2 0.44 7.03 0.53 1.23e-10 Vitiligo; TGCT cis rs1420338 1.000 rs918038 chr7:34153768 A/G cg01275685 chr7:34179230 BMPER -0.26 -4.83 -0.4 3.96e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs1451375 0.698 rs56766899 chr7:50648938 T/C cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs350251 0.899 rs350275 chr16:12233099 G/C cg01574788 chr16:12184133 SNX29 0.34 4.48 0.37 1.67e-5 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.572 rs3894322 chr3:10168965 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs4478858 0.647 rs11577679 chr1:31726185 T/C cg07478791 chr1:31886160 SERINC2 -0.52 -5.03 -0.41 1.67e-6 Alcohol dependence; TGCT trans rs2727020 0.894 rs2866361 chr11:49372481 A/G cg03929089 chr4:120376271 NA -0.67 -7.01 -0.53 1.38e-10 Coronary artery disease; TGCT cis rs9583531 0.760 rs9521916 chr13:111385509 A/G cg24331049 chr13:111365604 ING1 -0.6 -4.46 -0.37 1.8e-5 Coronary artery disease; TGCT cis rs11247915 0.569 rs869139 chr1:26527699 T/C cg23732845 chr1:26663426 AIM1L 0.32 4.52 0.38 1.45e-5 Obesity-related traits; TGCT cis rs7607369 0.714 rs1344643 chr2:219584975 G/C cg02176678 chr2:219576539 TTLL4 -0.49 -6.44 -0.5 2.34e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs1372520 0.748 rs990085 chr4:90754771 A/G cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs7020830 0.861 rs6476622 chr9:37308049 T/A cg14294708 chr9:37120828 ZCCHC7 1.17 15.12 0.81 6.56e-30 Schizophrenia; TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg16325326 chr1:53192061 ZYG11B 0.6 6.97 0.53 1.68e-10 Monocyte count; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg11905131 chr22:24372483 LOC391322 -0.95 -11.19 -0.71 1.64e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17001868 0.568 rs9611325 chr22:40782490 G/A cg07138101 chr22:40742427 ADSL 0.73 5.47 0.44 2.38e-7 Mammographic density (dense area); TGCT cis rs6540559 1.000 rs742215 chr1:209961023 A/T cg21951975 chr1:209979733 IRF6 0.66 5.69 0.45 8.77e-8 Cleft lip with or without cleft palate; TGCT cis rs13064411 0.696 rs869343 chr3:113226705 C/T cg10517650 chr3:113235015 CCDC52 -0.32 -4.45 -0.37 1.85e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs74417235 0.684 rs13186731 chr5:154056002 C/T cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs2439831 0.867 rs3101443 chr15:43912372 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.46 0.44 2.5e-7 Lung cancer in ever smokers; TGCT cis rs9522267 0.535 rs9515452 chr13:112234553 A/G cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs933688 0.941 rs6452954 chr5:90735692 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.2 0.59 2.51e-13 Smoking behavior; TGCT cis rs17741873 0.779 rs12572101 chr10:75600651 A/G cg07699608 chr10:75541558 CHCHD1 0.75 5.44 0.44 2.7e-7 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs1799949 0.965 rs11650913 chr17:41331597 T/C cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs7744392 0.557 rs6919334 chr6:35341875 G/A cg06087101 chr6:35551932 FKBP5 0.61 4.56 0.38 1.21e-5 Cataracts in type 2 diabetes; TGCT cis rs7811142 1.000 rs11764818 chr7:100043055 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs17345786 0.861 rs79181492 chr3:101216021 G/A cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7926906 0.840 rs7926034 chr11:90514796 A/G cg26138821 chr11:89956704 CHORDC1 -0.52 -5.55 -0.45 1.66e-7 Intelligence (multi-trait analysis); TGCT trans rs1005277 0.579 rs2474599 chr10:38438939 A/G cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.5e-21 Extrinsic epigenetic age acceleration; TGCT cis rs7192750 0.652 rs150617 chr16:72139396 T/C cg14768367 chr16:72042858 DHODH 0.86 4.51 0.38 1.47e-5 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.38e-6 Prudent dietary pattern; TGCT cis rs6952808 0.501 rs3778999 chr7:2180885 G/A cg04267008 chr7:1944627 MAD1L1 -0.34 -4.49 -0.37 1.63e-5 Bipolar disorder and schizophrenia; TGCT cis rs7804356 0.906 rs17323934 chr7:26904330 C/G cg03456212 chr7:26904342 SKAP2 0.6 4.57 0.38 1.16e-5 Type 1 diabetes; TGCT cis rs72945132 0.882 rs61177215 chr11:70129534 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg17554472 chr22:41940697 POLR3H -0.52 -5.37 -0.43 3.79e-7 Vitiligo; TGCT cis rs9522267 0.535 rs9522296 chr13:112234340 C/T cg10483660 chr13:112241077 NA 0.27 4.61 0.38 9.72e-6 Hepatitis; TGCT cis rs56399783 0.901 rs55767077 chr7:2774608 C/T cg19731401 chr7:2775893 GNA12 0.36 5.07 0.41 1.4e-6 Childhood ear infection; TGCT cis rs709400 0.598 rs11627529 chr14:104004557 C/T cg26031613 chr14:104095156 KLC1 0.89 9.8 0.66 3.77e-17 Body mass index; TGCT cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.716 rs11721453 chr4:99045485 G/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7588654 0.793 rs16859517 chr2:219949184 A/G cg19394737 chr2:219892361 CCDC108 0.35 4.55 0.38 1.27e-5 Height; TGCT cis rs10876993 0.928 rs2640631 chr12:58067532 A/T cg15848620 chr12:58087721 OS9 -0.73 -5.99 -0.47 2.12e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs8026198 0.568 rs58712247 chr15:42616288 C/CA cg20699549 chr15:42567973 GANC 0.33 4.98 0.41 2.06e-6 Fibrinogen levels; TGCT cis rs4906332 0.840 rs34161327 chr14:103857325 G/A cg26031613 chr14:104095156 KLC1 -0.52 -4.77 -0.39 5.12e-6 Coronary artery disease; TGCT cis rs6032067 0.561 rs2743317 chr20:43936931 C/T cg20256260 chr20:43936981 MATN4;RBPJL -0.32 -4.6 -0.38 1.02e-5 Blood protein levels; TGCT cis rs941408 0.515 rs759067 chr19:2775668 C/T cg06609049 chr19:2785107 THOP1 1.17 13.17 0.76 2.56e-25 Total cholesterol levels; TGCT cis rs12039431 0.706 rs61605574 chr1:37973943 G/A cg17933807 chr1:38061675 GNL2 -0.76 -7.21 -0.54 4.81e-11 Epithelial ovarian cancer; TGCT cis rs13064411 0.696 rs7610638 chr3:113139656 A/G cg10517650 chr3:113235015 CCDC52 -0.35 -4.63 -0.38 9.06e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2067615 0.579 rs1922438 chr12:107085171 C/G cg15890332 chr12:107067104 RFX4 0.3 5.88 0.47 3.6e-8 Heart rate; TGCT cis rs2302464 1.000 rs60913985 chr4:15728294 C/G cg18497811 chr4:14860861 NA -0.49 -4.5 -0.37 1.57e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs12188164 0.965 rs11745789 chr5:450777 T/C cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs10089 0.953 rs114881127 chr5:127369661 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs2980439 0.818 rs2948294 chr8:8094961 A/G cg15462221 chr8:8086144 FLJ10661 -0.57 -5.29 -0.43 5.23e-7 Neuroticism; TGCT cis rs28595532 0.844 rs116721336 chr4:119536538 A/G cg11846333 chr4:119757529 SEC24D 0.93 5.08 0.42 1.32e-6 Cannabis dependence symptom count; TGCT cis rs35146811 0.586 rs6946168 chr7:99598286 C/T cg13334819 chr7:99746414 C7orf59 -0.77 -6.67 -0.51 7.61e-10 Coronary artery disease; TGCT cis rs2742417 1.000 rs17328701 chr3:45734258 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1008375 1.000 rs7697889 chr4:17617961 G/T cg10189774 chr4:17578691 LAP3 0.54 4.78 0.39 4.9100000000000004e-06 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4711350 0.954 rs1536500 chr6:33723383 T/C cg18005901 chr6:33739558 LEMD2 -0.46 -4.96 -0.41 2.27e-6 Schizophrenia; TGCT cis rs35160687 0.901 rs7571424 chr2:86539160 A/G cg03171300 chr2:86307199 POLR1A 0.31 5.32 0.43 4.66e-7 Night sleep phenotypes; TGCT cis rs2204008 0.774 rs11615665 chr12:38328162 T/A cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs459571 0.792 rs55923934 chr9:136888233 C/G cg13789015 chr9:136890014 NCRNA00094 0.39 7.13 0.54 7.37e-11 Platelet distribution width; TGCT cis rs7197653 0.667 rs7190070 chr16:68353983 C/T cg05110241 chr16:68378359 PRMT7 -0.37 -4.5 -0.37 1.55e-5 Magnesium levels; TGCT cis rs13191362 0.935 rs66635391 chr6:162964577 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.17e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs116095464 0.558 rs9312977 chr5:221916 G/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs11190604 1.000 rs2295770 chr10:102239829 G/A cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg08219700 chr8:58056026 NA 0.4 4.87 0.4 3.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs7226408 0.857 rs72888928 chr18:34531073 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9517320 0.534 rs3825430 chr13:99129653 C/T cg07423050 chr13:99094983 FARP1 -0.28 -5.5 -0.44 2.06e-7 Longevity; TGCT cis rs17030434 0.911 rs115948674 chr4:154742052 G/T cg14289246 chr4:154710475 SFRP2 -0.9 -7.03 -0.53 1.2e-10 Electrocardiographic conduction measures; TGCT cis rs6901250 0.569 rs621486 chr6:117089143 T/C cg12892004 chr6:117198278 RFX6 0.37 4.77 0.39 5.09e-6 C-reactive protein levels; TGCT cis rs861020 0.630 rs585627 chr1:210004199 C/G cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs6912958 0.781 rs4334949 chr6:88290150 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs3617 0.573 rs4687682 chr3:52916939 T/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.52 -0.38 1.41e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs350251 0.934 rs183008 chr16:12201691 C/T cg01574788 chr16:12184133 SNX29 -0.35 -4.52 -0.38 1.45e-5 Intelligence (multi-trait analysis); TGCT cis rs12882406 0.607 rs4270088 chr14:23806190 A/G cg16420801 chr14:23816088 SLC22A17 -0.29 -4.74 -0.39 5.8e-6 Body mass index; TGCT cis rs6496667 0.642 rs62019395 chr15:91066309 G/T cg22089800 chr15:90895588 ZNF774 0.64 4.49 0.37 1.62e-5 Rheumatoid arthritis; TGCT cis rs12762955 0.507 rs10737004 chr10:1039019 T/C cg18964960 chr10:1102726 WDR37 -0.68 -5.93 -0.47 2.77e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs1552244 0.882 rs9312044 chr3:10037481 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs8016982 0.593 rs7160569 chr14:81713686 C/T cg01989461 chr14:81687754 GTF2A1 0.76 7.5 0.56 1.09e-11 Schizophrenia; TGCT cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs6545883 0.929 rs10200055 chr2:61628017 T/A cg15711740 chr2:61764176 XPO1 0.53 4.7 0.39 6.67e-6 Tuberculosis; TGCT cis rs12142240 0.770 rs112869704 chr1:46780285 C/T cg00530320 chr1:46809349 NSUN4 0.25 4.81 0.4 4.3e-6 Menopause (age at onset); TGCT cis rs57590327 0.503 rs7426937 chr3:81881360 T/C cg07356753 chr3:81810745 GBE1 -0.65 -5.67 -0.45 9.68e-8 Extraversion; TGCT cis rs35306767 0.953 rs10904583 chr10:983498 T/C cg26597838 chr10:835615 NA 0.56 7.7 0.57 3.66e-12 Eosinophil percentage of granulocytes; TGCT cis rs4294134 0.608 rs11760746 chr7:135244015 G/A cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs6088580 0.634 rs4911421 chr20:32998948 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs6582630 0.519 rs11514078 chr12:38408817 G/C cg26384229 chr12:38710491 ALG10B 0.87 7.8 0.57 2.17e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs3796352 1.000 rs71301808 chr3:53085577 C/G cg07884673 chr3:53033167 SFMBT1 0.58 5.99 0.47 2.11e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9674544 0.646 rs8069452 chr17:47140999 A/G cg20966754 chr17:47091339 IGF2BP1 0.42 4.96 0.41 2.25e-6 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs10493773 0.532 rs12064199 chr1:86187073 A/T cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.2 -0.59 2.63e-13 Urate levels in overweight individuals; TGCT cis rs9311474 0.607 rs4687625 chr3:52563718 C/T cg10802521 chr3:52805072 NEK4 -0.73 -8.95 -0.63 4.37e-15 Electroencephalogram traits; TGCT cis rs10197940 0.624 rs3771901 chr2:152432481 G/A cg06191203 chr2:152266755 RIF1 -0.76 -7.24 -0.55 4.11e-11 Lung cancer; TGCT cis rs2439831 0.867 rs2264876 chr15:43757419 G/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.18 0.59 2.83e-13 Lung cancer in ever smokers; TGCT cis rs4494114 0.967 rs7532880 chr1:39297734 T/C cg25970120 chr1:39325951 RRAGC -0.66 -6.8 -0.52 3.99e-10 Blood protein levels; TGCT cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs7572733 0.534 rs700688 chr2:198723833 A/G cg00792783 chr2:198669748 PLCL1 -0.55 -4.92 -0.4 2.68e-6 Dermatomyositis; TGCT cis rs1215050 0.765 rs687795 chr4:98754912 C/G cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3020736 0.500 rs7364293 chr22:42506370 C/T cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs1878931 0.582 rs27232 chr16:3436782 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.4 -0.5 2.83e-9 Body mass index (adult); TGCT cis rs7666738 0.830 rs7697315 chr4:98938764 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.8e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7954584 0.567 rs11043233 chr12:122330733 C/T cg22618164 chr12:122356400 WDR66 0.66 6.28 0.49 5.32e-9 Mean corpuscular volume; TGCT cis rs11098499 0.743 rs11098501 chr4:120252017 T/G cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9858542 0.953 rs34588335 chr3:49407660 G/C cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs4654899 0.680 rs3890762 chr1:21198265 G/A cg01072550 chr1:21505969 NA 0.55 8.93 0.63 4.85e-15 Superior frontal gyrus grey matter volume; TGCT cis rs4819052 0.851 rs2236444 chr21:46678226 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.8 6.94 0.53 1.9e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs526231 0.819 rs568999 chr5:102601358 G/C cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs6896969 0.510 rs7730306 chr5:40423257 C/A cg01087697 chr5:40835557 RPL37 0.56 5.03 0.41 1.69e-6 Multiple sclerosis; TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs1801251 1.000 rs6761324 chr2:233582793 T/G cg25237894 chr2:233734115 C2orf82 0.32 5.81 0.46 5.01e-8 Coronary artery disease; TGCT cis rs523522 0.962 rs4767903 chr12:120930046 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs35146811 0.807 rs6465761 chr7:99620277 G/C cg13334819 chr7:99746414 C7orf59 -0.81 -7.25 -0.55 3.95e-11 Coronary artery disease; TGCT cis rs2243480 0.666 rs1880311 chr7:65276752 G/C cg20637647 chr7:64974828 NA -0.96 -4.95 -0.41 2.4e-6 Diabetic kidney disease; TGCT cis rs7618915 0.501 rs6804145 chr3:52694198 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs2201728 1.000 rs6818892 chr4:100158920 G/C cg07219303 chr4:100140905 ADH6 -0.35 -5.22 -0.42 7.29e-7 Cardiac Troponin-T levels; TGCT cis rs10088262 0.540 rs6988602 chr8:124788502 C/T cg20713898 chr8:124780851 FAM91A1 0.78 5.43 0.44 2.84e-7 Pancreatic cancer; TGCT cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg08859206 chr1:53392774 SCP2 -0.4 -6.07 -0.48 1.47e-8 Monocyte count; TGCT cis rs7296418 0.738 rs10846489 chr12:123743927 A/G cg00376283 chr12:123451042 ABCB9 -0.74 -6.67 -0.51 7.62e-10 Platelet count; TGCT cis rs13242816 1.000 rs13235720 chr7:116113663 T/C cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs17376456 0.877 rs7734897 chr5:93305402 G/A cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs861020 0.630 rs686582 chr1:210008673 A/C cg05527609 chr1:210001259 C1orf107 0.89 8.36 0.6 1.08e-13 Orofacial clefts; TGCT cis rs13191362 1.000 rs13207671 chr6:162979056 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs651907 0.535 rs12631513 chr3:101517476 A/C cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs7666738 0.609 rs35214820 chr4:98864692 G/A cg24818145 chr4:99064322 C4orf37 0.53 4.52 0.38 1.41e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs832540 0.629 rs10940512 chr5:56082094 G/C cg12311346 chr5:56204834 C5orf35 -0.47 -4.79 -0.4 4.6e-6 Coronary artery disease; TGCT cis rs3751972 0.590 rs71372355 chr17:26265885 C/A cg02948944 chr17:26242737 NA -0.46 -5.6 -0.45 1.31e-7 Fractional exhaled nitric oxide (childhood); TGCT trans rs4650994 1.000 rs17276527 chr1:178520680 G/A cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.54e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4819052 0.565 rs35776291 chr21:46706142 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.64 6.31 0.49 4.59e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs950169 1.000 rs12902672 chr15:84716986 G/A cg11189052 chr15:85197271 WDR73 0.7 5.94 0.47 2.64e-8 Schizophrenia; TGCT cis rs916888 0.610 rs199438 chr17:44791643 G/A cg01570182 chr17:44337453 NA 0.74 7.02 0.53 1.29e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg00814883 chr7:100076585 TSC22D4 -0.91 -9.48 -0.65 2.3e-16 Platelet count; TGCT cis rs2412208 0.545 rs2275910 chr1:7068679 A/G cg09549827 chr1:6484616 ESPN 0.27 4.72 0.39 6.38e-6 Survival in sporadic amyotrophic lateral sclerosis; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg00024416 chr22:24240387 NA -0.25 -4.71 -0.39 6.61e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3845702 0.736 rs16867131 chr2:180848651 A/G cg01881094 chr2:180872142 CWC22 -0.99 -6.3 -0.49 4.76e-9 Schizophrenia; TGCT cis rs10256972 0.521 rs7457418 chr7:1110255 C/T cg03188948 chr7:1209495 NA 0.47 5.65 0.45 1.04e-7 Longevity;Endometriosis; TGCT cis rs6912958 0.514 rs1980792 chr6:87889917 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.66 -6.67 -0.51 7.5e-10 Monocyte percentage of white cells; TGCT cis rs10461617 0.617 rs1423623 chr5:56065575 A/G cg24531977 chr5:56204891 C5orf35 0.5 5.08 0.42 1.35e-6 Type 2 diabetes; TGCT cis rs1153858 1.000 rs2056493 chr15:45648272 A/G cg26924012 chr15:45694286 SPATA5L1 1.08 15.28 0.81 2.78e-30 Homoarginine levels; TGCT cis rs13256369 0.802 rs13281933 chr8:8562665 C/A cg18904891 chr8:8559673 CLDN23 0.58 5.4 0.44 3.23e-7 Obesity-related traits; TGCT cis rs12477438 0.501 rs12613624 chr2:99732741 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -1.05 -14.89 -0.8 2.21e-29 Chronic sinus infection; TGCT cis rs7666738 0.830 rs7657179 chr4:98948569 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4285028 0.699 rs6771068 chr3:121478745 A/T cg01951420 chr3:121553821 IQCB1;EAF2 1.03 8.69 0.62 1.84e-14 Multiple sclerosis; TGCT cis rs9398235 0.673 rs2073210 chr6:110729973 A/C cg19196401 chr6:110721138 DDO -0.46 -4.47 -0.37 1.77e-5 Systemic lupus erythematosus; TGCT cis rs10256972 0.616 rs4998392 chr7:1113344 A/C cg03188948 chr7:1209495 NA 0.43 5.56 0.45 1.6e-7 Longevity;Endometriosis; TGCT cis rs877282 0.898 rs11253347 chr10:765769 A/G cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs3796352 1.000 rs71301808 chr3:53085577 C/G cg15956490 chr3:53032818 SFMBT1 0.57 6.52 0.51 1.59e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1976403 0.633 rs1780324 chr1:21821757 A/G cg17800788 chr1:21766015 NBPF3 0.25 4.58 0.38 1.1e-5 Liver enzyme levels (alkaline phosphatase); TGCT trans rs561341 1.000 rs55643307 chr17:30263074 T/C cg20587970 chr11:113659929 NA -0.9 -7.84 -0.58 1.78e-12 Hip circumference adjusted for BMI; TGCT cis rs9787249 0.874 rs7520588 chr1:40214525 T/A cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs7010267 0.740 rs11573885 chr8:119949165 T/C cg17171407 chr8:119960777 TNFRSF11B -0.25 -4.44 -0.37 2e-5 Total body bone mineral density (age 45-60); TGCT cis rs7226408 0.857 rs72887089 chr18:34506836 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs10193935 0.901 rs6727657 chr2:42632117 A/G cg27598129 chr2:42591480 NA -0.37 -5.23 -0.42 7.1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11671005 0.735 rs3764529 chr19:58945089 A/G cg13877915 chr19:58951672 ZNF132 0.63 5.0 0.41 1.95e-6 Mean platelet volume; TGCT cis rs11676348 0.755 rs13410318 chr2:219022910 T/G cg00012203 chr2:219082015 ARPC2 0.54 5.2 0.42 7.86e-7 Ulcerative colitis; TGCT cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg16497277 chr3:49208875 KLHDC8B -0.54 -5.17 -0.42 9.07e-7 Menarche (age at onset); TGCT cis rs9611565 0.546 rs132793 chr22:42063681 A/G cg03806693 chr22:41940476 POLR3H 1.06 11.07 0.71 3.09e-20 Vitiligo; TGCT cis rs709400 0.628 rs72708854 chr14:103864885 T/C cg26031613 chr14:104095156 KLC1 0.85 9.32 0.64 5.54e-16 Body mass index; TGCT trans rs66573146 1.000 rs6812771 chr4:6964048 G/A cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs4363385 0.510 rs6677674 chr1:153037601 A/G cg04546999 chr1:152956429 SPRR1A -0.26 -4.63 -0.38 9.15e-6 Inflammatory skin disease; TGCT cis rs2115630 1.000 rs11854291 chr15:85363708 T/C cg11189052 chr15:85197271 WDR73 -0.62 -5.89 -0.47 3.35e-8 P wave terminal force; TGCT cis rs617219 0.737 rs13158309 chr5:78463395 C/T cg23987322 chr5:78407566 BHMT -0.36 -4.83 -0.4 4.01e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs12477438 0.798 rs972768 chr2:99682397 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs11031096 0.628 rs10835735 chr11:4211865 G/C cg18678763 chr11:4115507 RRM1 -0.45 -5.83 -0.46 4.41e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2204008 0.580 rs36118148 chr12:38411812 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Bladder cancer; TGCT cis rs7647973 0.593 rs7652179 chr3:49808618 T/A cg05785598 chr3:49045655 WDR6 -0.42 -4.88 -0.4 3.23e-6 Menarche (age at onset); TGCT cis rs1865760 0.551 rs9461230 chr6:26019240 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.55 0.56 8.31e-12 Height; TGCT cis rs7809950 0.678 rs7788330 chr7:106985648 G/T cg23024343 chr7:107201750 COG5 -0.43 -5.85 -0.47 4.12e-8 Coronary artery disease; TGCT cis rs7647973 1.000 rs2140270 chr3:49439440 A/G cg05785598 chr3:49045655 WDR6 -0.4 -4.67 -0.39 7.57e-6 Menarche (age at onset); TGCT cis rs9393777 0.513 rs1104871 chr6:26665235 T/G cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.5 -4.72 -0.39 6.15e-6 Intelligence (multi-trait analysis); TGCT cis rs7258465 1.000 rs8103622 chr19:18572834 C/T cg06462663 chr19:18546047 ISYNA1 0.21 4.63 0.38 9.14e-6 Breast cancer; TGCT cis rs13256369 0.802 rs11249885 chr8:8562008 C/T cg17143192 chr8:8559678 CLDN23 0.54 5.09 0.42 1.31e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs13124904 chr4:98856973 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7635838 0.684 rs2594965 chr3:11323799 G/C cg00170343 chr3:11313890 ATG7 0.64 6.35 0.5 3.65e-9 HDL cholesterol; TGCT cis rs1670533 1.000 rs11731320 chr4:1057916 T/A cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs2380220 0.541 rs72928283 chr6:96082490 A/C cg04719120 chr6:96025338 MANEA -0.69 -5.11 -0.42 1.18e-6 Behavioural disinhibition (generation interaction); TGCT trans rs797680 0.856 rs687394 chr1:93713917 G/A cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9326248 0.817 rs1242127 chr11:117076564 A/G cg11861562 chr11:117069780 TAGLN -0.28 -4.57 -0.38 1.17e-5 Blood protein levels; TGCT cis rs9916302 0.904 rs6503519 chr17:37706578 A/G cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs4372836 1.000 rs4549034 chr2:28972579 C/T cg09522027 chr2:28974177 PPP1CB -0.59 -5.15 -0.42 1e-6 Body mass index; TGCT cis rs319204 0.877 rs640656 chr5:146287119 G/A cg25021259 chr5:146258546 PPP2R2B 0.35 4.52 0.38 1.4e-5 Schizophrenia; TGCT trans rs9348739 1 rs9348739 chr6:26923099 G/C cg15633603 chr2:190399258 NA 0.4 6.95 0.53 1.81e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs8180040 0.726 rs4078466 chr3:47126543 C/T cg27129171 chr3:47204927 SETD2 0.76 9.8 0.66 3.91e-17 Colorectal cancer; TGCT cis rs1629083 0.967 rs1715456 chr11:118123517 A/G cg16594165 chr11:118135105 MPZL2 -0.34 -4.75 -0.39 5.6e-6 Lung cancer; TGCT cis rs9300255 0.568 rs1790102 chr12:123704890 G/A cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs806215 0.526 rs114283033 chr7:127530017 G/A cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.46e-6 Type 2 diabetes; TGCT cis rs7647973 0.580 rs11716334 chr3:49230096 G/A cg06212747 chr3:49208901 KLHDC8B 0.65 6.23 0.49 6.72e-9 Menarche (age at onset); TGCT cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs13191362 0.935 rs35942036 chr6:163163297 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.96 7.62 0.56 5.6e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11209002 0.614 rs7552205 chr1:67551741 C/A cg02640540 chr1:67518911 SLC35D1 0.55 4.65 0.39 8.42e-6 Crohn's disease; TGCT cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT trans rs1814175 0.781 rs28681334 chr11:50051177 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs4253772 0.591 rs739165 chr22:46684528 C/T cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg03188948 chr7:1209495 NA 0.46 6.15 0.48 9.9e-9 Longevity;Endometriosis; TGCT cis rs78487399 0.808 rs10189235 chr2:43745520 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.87 -0.4 3.28e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7208859 0.524 rs59913838 chr17:29101563 A/T cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs35146811 0.625 rs858514 chr7:99825748 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs6570726 0.599 rs455001 chr6:145854450 A/T cg23711669 chr6:146136114 FBXO30 0.7 6.44 0.5 2.41e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10782582 0.609 rs2029680 chr1:76363505 A/C cg10523679 chr1:76189770 ACADM -0.58 -5.31 -0.43 4.92e-7 Daytime sleep phenotypes; TGCT cis rs2115630 0.967 rs7171167 chr15:85239123 A/T cg11189052 chr15:85197271 WDR73 -0.66 -6.45 -0.5 2.24e-9 P wave terminal force; TGCT cis rs263156 1.000 rs263156 chr6:142907515 T/G cg18419694 chr6:143832440 FUCA2 -0.4 -4.65 -0.39 8.22e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs7107174 0.688 rs2063724 chr11:78133077 T/C cg12700464 chr11:78128424 GAB2 -0.69 -4.6 -0.38 1.03e-5 Testicular germ cell tumor; TGCT cis rs7666738 0.830 rs1876192 chr4:98727555 T/C cg05340658 chr4:99064831 C4orf37 0.49 5.77 0.46 6.02e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs483180 0.531 rs541503 chr1:120208297 A/G cg19096424 chr1:120255104 PHGDH -0.57 -5.35 -0.43 4.02e-7 Macular telangiectasia type 2; TGCT cis rs6940638 0.531 rs12211984 chr6:26986054 G/C cg07220782 chr6:26987966 LOC100270746;C6orf41 0.4 4.47 0.37 1.76e-5 Intelligence (multi-trait analysis); TGCT cis rs33794 0.901 rs33780 chr3:45289715 C/T cg18645101 chr3:44551900 NA 0.55 4.82 0.4 4.08e-6 Lung function (forced expiratory volume in 1 second); TGCT cis rs2594989 0.887 rs2442797 chr3:11555935 C/T cg26283222 chr3:11613257 VGLL4 -0.25 -5.35 -0.43 4.07e-7 Circulating chemerin levels; TGCT cis rs17331151 0.512 rs9637477 chr3:52891426 G/C cg07884673 chr3:53033167 SFMBT1 -0.5 -5.77 -0.46 5.86e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs34779708 0.931 rs35126129 chr10:35452141 G/A cg04310649 chr10:35416472 CREM -0.53 -4.71 -0.39 6.66e-6 Inflammatory bowel disease;Crohn's disease; TGCT trans rs10953454 1.000 rs10216243 chr7:104513624 G/T cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.54e-10 Obesity; TGCT cis rs9581857 0.725 rs117947621 chr13:28022267 T/C cg22138327 chr13:27999177 GTF3A 0.78 5.57 0.45 1.51e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.720 rs7752286 chr6:146072662 C/T cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.844 rs1555330 chr20:25232097 A/C cg03522245 chr20:25566470 NINL 0.57 5.67 0.45 9.54e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1799949 1.000 rs3092994 chr17:41215825 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 4.97 0.41 2.14e-6 Menopause (age at onset); TGCT cis rs4919694 0.901 rs10509763 chr10:104776391 G/A cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs1008375 0.966 rs4698619 chr4:17580955 G/A cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.595 rs36081958 chr8:58117505 C/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs698833 0.509 rs6715202 chr2:44516282 A/G cg23552047 chr2:44669647 C2orf34 0.29 4.65 0.39 8.25e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs10883723 0.738 rs715438 chr10:104258303 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs11671005 0.616 rs12980907 chr19:58956326 C/T cg13877915 chr19:58951672 ZNF132 0.62 4.89 0.4 3.06e-6 Mean platelet volume; TGCT cis rs8062405 1.000 rs62037364 chr16:28868695 G/A cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs10883723 0.703 rs7898410 chr10:104245858 T/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs319204 1.000 rs561789 chr5:146242078 C/G cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg13695892 chr22:41940480 POLR3H -0.89 -9.04 -0.63 2.61e-15 Vitiligo; TGCT cis rs28595532 0.668 rs56410164 chr4:119331625 A/G cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs1008375 0.897 rs2315554 chr4:17660407 T/C cg18681998 chr4:17616180 MED28 0.96 10.34 0.68 1.84e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg20007245 chr22:24372913 LOC391322 -0.78 -6.92 -0.53 2.19e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT trans rs10953454 1.000 rs10262655 chr7:104480132 G/T cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs4746818 0.892 rs2394505 chr10:70871598 A/G cg04149295 chr10:70884716 VPS26A -0.68 -4.56 -0.38 1.19e-5 Left atrial antero-posterior diameter; TGCT cis rs17152411 0.895 rs11245420 chr10:126586469 T/C cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs2013441 1.000 rs972966 chr17:20030992 G/C cg18979559 chr17:20280153 CCDC144C 0.46 4.83 0.4 3.92e-6 Obesity-related traits; TGCT cis rs17539620 0.624 rs7770107 chr6:154836862 A/G cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs3821902 0.646 rs55955229 chr3:64015425 T/C cg22134162 chr3:63841271 THOC7 -0.32 -4.85 -0.4 3.7e-6 Breast cancer; TGCT cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg18402987 chr7:1209562 NA 0.67 5.93 0.47 2.77e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9914544 0.933 rs11871889 chr17:18771425 T/C cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.41 1.36e-6 Educational attainment (years of education); TGCT cis rs896854 0.812 rs2340586 chr8:95969261 G/A cg09323728 chr8:95962352 TP53INP1 -0.54 -6.89 -0.53 2.54e-10 Type 2 diabetes; TGCT cis rs782590 0.783 rs7594279 chr2:55812073 T/G cg03859395 chr2:55845619 SMEK2 0.91 11.16 0.71 1.9e-20 Metabolic syndrome; TGCT cis rs13242816 0.881 rs35037267 chr7:116117587 A/T cg02799643 chr7:116139180 CAV2 -0.49 -5.61 -0.45 1.27e-7 P wave duration; TGCT cis rs12580194 0.556 rs61249728 chr12:55728922 A/G cg10672482 chr12:55725839 OR6C3 -0.56 -4.89 -0.4 3.1e-6 Cancer; TGCT cis rs7811142 1.000 rs11771419 chr7:99988403 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs17376456 0.825 rs28534784 chr5:93063332 C/A cg21475434 chr5:93447410 FAM172A 0.66 5.15 0.42 9.97e-7 Diabetic retinopathy; TGCT cis rs76473307 1.000 rs6026538 chr20:57389420 C/T cg06163629 chr20:57414884 GNASAS;GNAS 0.62 4.65 0.39 8.25e-6 Chronic lymphocytic leukemia; TGCT cis rs7975161 0.572 rs7299669 chr12:104568919 C/T cg25273343 chr12:104657179 TXNRD1 -0.44 -5.61 -0.45 1.26e-7 Toenail selenium levels; TGCT cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg11062466 chr8:58055876 NA 0.44 4.68 0.39 7.38e-6 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.557 rs1680030 chr4:1245500 A/T cg20887711 chr4:1340912 KIAA1530 -0.71 -6.43 -0.5 2.45e-9 Obesity-related traits; TGCT cis rs4803455 0.565 rs11670143 chr19:41864971 A/G cg09537434 chr19:41945824 ATP5SL -0.54 -5.28 -0.43 5.66e-7 Migraine;Coronary artery disease; TGCT cis rs6657613 0.903 rs9435734 chr1:17311190 A/G cg21692666 chr1:17199302 NA -0.42 -4.54 -0.38 1.31e-5 Hip circumference adjusted for BMI; TGCT cis rs2710642 0.849 rs4671450 chr2:62981869 C/A cg17519650 chr2:63277830 OTX1 -0.58 -5.06 -0.41 1.48e-6 LDL cholesterol levels;LDL cholesterol; TGCT cis rs2933343 0.630 rs75824035 chr3:128652985 T/C cg11901034 chr3:128598214 ACAD9 -0.67 -6.43 -0.5 2.46e-9 IgG glycosylation; TGCT cis rs9972944 0.702 rs6416947 chr17:63763970 C/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.29 -0.43 5.45e-7 Total body bone mineral density; TGCT cis rs372883 0.648 rs1153291 chr21:30689070 G/T cg24692254 chr21:30365293 RNF160 -0.53 -4.64 -0.38 8.82e-6 Pancreatic cancer; TGCT cis rs644148 0.730 rs2686766 chr19:44991595 T/G cg15540054 chr19:45004280 ZNF180 -0.61 -4.49 -0.37 1.62e-5 Personality dimensions; TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg09436375 chr6:42928200 GNMT -0.4 -5.16 -0.42 9.7e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10504229 0.953 rs6991035 chr8:58183374 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9303401 0.659 rs7224276 chr17:56897827 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs42648 0.617 rs11563435 chr7:89900207 A/C cg25739043 chr7:89950458 NA -0.55 -5.12 -0.42 1.13e-6 Homocysteine levels; TGCT cis rs7824557 0.606 rs2736270 chr8:11192593 G/A cg21775007 chr8:11205619 TDH 0.73 6.97 0.53 1.68e-10 Retinal vascular caliber; TGCT cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg23719950 chr11:63933701 MACROD1 -0.7 -5.91 -0.47 3.09e-8 Mean platelet volume; TGCT cis rs3087591 0.960 rs2905794 chr17:29470002 G/A cg24425628 chr17:29625626 OMG;NF1 0.49 7.74 0.57 2.97e-12 Hip circumference; TGCT cis rs7223966 1.000 rs13380863 chr17:61780793 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.6 0.38 1.04e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg20276088 chr3:133502917 NA -0.3 -6.27 -0.49 5.42e-9 Iron status biomarkers; TGCT cis rs72781680 0.898 rs12623316 chr2:24087857 A/G cg08917208 chr2:24149416 ATAD2B 0.77 4.69 0.39 7.06e-6 Lymphocyte counts; TGCT cis rs9341808 0.718 rs10080237 chr6:80854470 T/C cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs9788333 0.962 rs12584792 chr13:21887208 C/T cg04632378 chr13:21900426 NA 0.43 5.04 0.41 1.6e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs12497850 0.931 rs13064911 chr3:48952385 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs6918586 0.636 rs198817 chr6:26126524 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.68 -6.46 -0.5 2.13e-9 Schizophrenia; TGCT cis rs1532993 0.518 rs1508461 chr4:98582199 T/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.8 -0.4 4.45e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs858239 0.601 rs929507 chr7:23166664 G/C cg05602783 chr7:23145260 KLHL7 -0.65 -5.48 -0.44 2.32e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6840360 0.571 rs62327274 chr4:152548012 C/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs897984 0.683 rs13337900 chr16:30822409 G/A cg02466173 chr16:30829666 NA -0.28 -4.65 -0.39 8.2e-6 Dementia with Lewy bodies; TGCT cis rs7208859 0.524 rs11653098 chr17:29122501 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7681440 0.904 rs28750169 chr4:90774303 A/G cg26578617 chr4:90757533 SNCA -0.46 -4.73 -0.39 6.01e-6 Dementia with Lewy bodies; TGCT cis rs2832191 0.791 rs2832197 chr21:30497790 T/C cg08807101 chr21:30365312 RNF160 -0.62 -5.8 -0.46 5.14e-8 Dental caries; TGCT cis rs7267979 0.966 rs2482923 chr20:25308981 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs896854 0.967 rs13257021 chr8:95965695 A/G cg16049864 chr8:95962084 TP53INP1 -0.77 -10.92 -0.7 7.16e-20 Type 2 diabetes; TGCT cis rs4927850 0.501 rs9881504 chr3:195656614 A/G cg12923728 chr3:195709715 SDHAP1 -0.26 -4.96 -0.41 2.31e-6 Pancreatic cancer; TGCT cis rs6558174 0.965 rs6558172 chr8:22492052 C/T cg03733263 chr8:22462867 KIAA1967 0.62 4.96 0.41 2.26e-6 Breast cancer; TGCT cis rs921968 0.573 rs684776 chr2:219324016 T/C cg02176678 chr2:219576539 TTLL4 0.49 6.82 0.52 3.62e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6490294 0.904 rs11066098 chr12:112388128 A/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs11718455 0.960 rs34241796 chr3:44000394 A/T cg08738300 chr3:44038990 NA 0.83 6.19 0.49 8.13e-9 Coronary artery disease; TGCT cis rs2153535 0.580 rs9328483 chr6:8521295 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs11785400 0.963 rs6990126 chr8:143728387 T/C cg10596483 chr8:143751796 JRK 0.54 5.84 0.46 4.34e-8 Schizophrenia; TGCT cis rs595982 0.527 rs73061658 chr19:49372376 G/C cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.16 -0.64 1.35e-15 Red cell distribution width; TGCT cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7246657 0.943 rs7255952 chr19:37988797 A/G cg18154014 chr19:37997991 ZNF793 0.8 5.47 0.44 2.33e-7 Coronary artery calcification; TGCT cis rs2836974 0.831 rs4375956 chr21:40521788 G/A cg11890956 chr21:40555474 PSMG1 1.11 12.1 0.74 9.93e-23 Cognitive function; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg11141652 chr22:24348549 GSTTP1 -0.35 -4.85 -0.4 3.67e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10256972 0.721 rs2030959 chr7:1075906 T/C cg03188948 chr7:1209495 NA 0.45 5.88 0.47 3.56e-8 Longevity;Endometriosis; TGCT cis rs17270561 0.887 rs717551 chr6:25855624 T/C cg16482183 chr6:26056742 HIST1H1C 0.86 5.62 0.45 1.2e-7 Iron status biomarkers; TGCT cis rs2762353 0.574 rs9467570 chr6:25699283 C/A cg15691649 chr6:25882328 NA 0.51 5.98 0.47 2.2e-8 Blood metabolite levels; TGCT cis rs6977660 0.714 rs10251774 chr7:19790489 T/C cg05791153 chr7:19748676 TWISTNB 0.88 5.05 0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs7552404 0.924 rs114752222 chr1:76180878 C/T cg10523679 chr1:76189770 ACADM 0.9 9.92 0.67 2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7635838 0.892 rs7372723 chr3:11466511 G/A cg00170343 chr3:11313890 ATG7 0.66 6.25 0.49 6.1e-9 HDL cholesterol; TGCT cis rs4144743 1.000 rs4144744 chr17:45323262 A/G cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs10892173 0.566 rs10892174 chr11:117672565 A/C cg07621104 chr11:117668040 DSCAML1 0.73 7.95 0.58 9.58e-13 Myopia; TGCT cis rs9435341 0.929 rs1762509 chr1:107592959 A/G cg09367891 chr1:107599246 PRMT6 -0.64 -5.5 -0.44 2.07e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs208520 0.690 rs4710311 chr6:66823223 C/T cg07460842 chr6:66804631 NA -0.86 -8.29 -0.6 1.54e-13 Exhaled nitric oxide output; TGCT cis rs1552244 1.000 rs17032396 chr3:10153559 A/G cg00149659 chr3:10157352 C3orf10 -0.94 -6.0 -0.47 2e-8 Alzheimer's disease; TGCT cis rs2836633 0.929 rs2836602 chr21:40039169 A/T cg05519781 chr21:40033154 ERG -0.68 -6.71 -0.52 6.27e-10 Coronary artery disease; TGCT cis rs5769707 0.632 rs135877 chr22:50014002 A/G cg05373962 chr22:49881684 NA -0.29 -4.92 -0.4 2.7e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10504229 0.679 rs11783444 chr8:58131267 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs2228479 0.702 rs62056087 chr16:89920383 C/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs4819052 0.679 rs2255761 chr21:46683622 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.62 6.01 0.47 1.93e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs66823261 0.778 rs2906332 chr8:194943 C/T cg27532244 chr8:182981 ZNF596;RPL23AP53 -0.89 -7.16 -0.54 6.2e-11 Breast cancer (estrogen-receptor negative);Breast cancer; TGCT cis rs801193 1.000 rs10234018 chr7:66146284 A/T cg18876405 chr7:65276391 NA -0.32 -4.82 -0.4 4.1e-6 Aortic root size; TGCT cis rs3008870 1.000 rs1137656 chr1:67451602 A/C cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs7804356 1.000 rs3801842 chr7:26830263 C/T cg03456212 chr7:26904342 SKAP2 -0.63 -4.88 -0.4 3.19e-6 Type 1 diabetes; TGCT cis rs1799949 1.000 rs8077486 chr17:41212805 C/T cg10047753 chr17:41438598 NA 0.76 6.86 0.52 2.95e-10 Menopause (age at onset); TGCT cis rs7647973 0.626 rs11720705 chr3:49753788 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs2204008 0.502 rs2387275 chr12:38142836 G/A cg13010199 chr12:38710504 ALG10B 0.69 5.38 0.43 3.59e-7 Bladder cancer; TGCT cis rs28386778 0.897 rs2727326 chr17:61923016 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs7647973 1.000 rs2312462 chr3:49601255 A/G cg05785598 chr3:49045655 WDR6 0.38 4.65 0.39 8.31e-6 Menarche (age at onset); TGCT cis rs1799949 1.000 rs34942571 chr17:41273379 G/C cg23758822 chr17:41437982 NA 0.72 6.91 0.53 2.23e-10 Menopause (age at onset); TGCT cis rs2721195 0.549 rs2958492 chr8:145919126 C/T cg12270520 chr8:146023939 ZNF517 0.5 4.44 0.37 1.94e-5 Age at first birth; TGCT cis rs12142240 0.698 rs6690075 chr1:46819848 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs9325144 0.600 rs61931871 chr12:38829889 G/A cg26384229 chr12:38710491 ALG10B -0.57 -5.12 -0.42 1.14e-6 Morning vs. evening chronotype; TGCT trans rs9951602 0.512 rs9946115 chr18:76654531 A/C cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs2180341 0.574 rs13192350 chr6:127677762 G/T cg24812749 chr6:127587940 RNF146 0.62 5.14 0.42 1.04e-6 Breast cancer; TGCT cis rs13108904 0.905 rs34490749 chr4:1217981 A/G cg05665937 chr4:1216051 CTBP1 0.26 5.12 0.42 1.13e-6 Obesity-related traits; TGCT cis rs250677 0.559 rs17109198 chr5:148369712 C/T cg18129178 chr5:148520854 ABLIM3 -0.36 -4.69 -0.39 7.23e-6 Breast cancer; TGCT cis rs9467773 0.506 rs9393709 chr6:26365147 C/T cg15659132 chr6:26577336 NA -0.5 -5.05 -0.41 1.53e-6 Intelligence (multi-trait analysis); TGCT cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg11301795 chr4:187892539 NA -0.3 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs155076 0.702 rs482731 chr13:21846075 G/A cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.63e-9 Blood metabolite levels; TGCT cis rs35146811 0.660 rs6465760 chr7:99591418 A/G cg13334819 chr7:99746414 C7orf59 0.65 5.76 0.46 6.21e-8 Coronary artery disease; TGCT cis rs12142240 0.698 rs6667861 chr1:46815749 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 6.09 0.48 1.32e-8 Mean platelet volume; TGCT cis rs7666738 0.830 rs1593570 chr4:99017058 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7726839 0.540 rs72703087 chr5:598029 C/T cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs17030434 0.822 rs7686027 chr4:154680269 T/G cg14289246 chr4:154710475 SFRP2 0.9 7.0 0.53 1.41e-10 Electrocardiographic conduction measures; TGCT cis rs896854 0.812 rs4582532 chr8:95969257 G/A cg13393036 chr8:95962371 TP53INP1 -0.65 -8.82 -0.62 8.57e-15 Type 2 diabetes; TGCT cis rs1371867 0.846 rs1788196 chr8:101290088 C/T cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs2303759 0.830 rs7257053 chr19:49894456 C/G cg22307029 chr19:49891270 CCDC155 0.56 5.34 0.43 4.27e-7 Multiple sclerosis; TGCT cis rs28386778 0.863 rs1376110 chr17:61779927 A/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.52 4.77 0.39 5.18e-6 Prudent dietary pattern; TGCT cis rs10791323 0.604 rs2257010 chr11:133712348 G/A cg03690763 chr11:133734501 NA -0.32 -5.07 -0.41 1.4e-6 Childhood ear infection; TGCT cis rs4803468 0.905 rs284662 chr19:41932275 T/C cg09537434 chr19:41945824 ATP5SL -0.88 -9.46 -0.65 2.61e-16 Height; TGCT cis rs4665809 0.567 rs6546848 chr2:26444414 G/C cg25036284 chr2:26402008 FAM59B -0.65 -5.18 -0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs2836950 0.565 rs8134214 chr21:40542367 A/C cg06238570 chr21:40685208 BRWD1 -0.63 -6.48 -0.5 1.95e-9 Menarche (age at onset); TGCT cis rs6964587 1.000 rs2301559 chr7:91746727 T/C cg22709100 chr7:91322751 NA 0.29 4.66 0.39 8e-6 Breast cancer; TGCT cis rs514406 0.548 rs6670871 chr1:53212082 A/C cg08859206 chr1:53392774 SCP2 0.36 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs9910055 0.529 rs170637 chr17:42186868 C/T cg19774624 chr17:42201019 HDAC5 0.78 7.55 0.56 8.01e-12 Total body bone mineral density; TGCT cis rs67311347 0.544 rs2887965 chr3:40334154 A/G cg13683864 chr3:40499215 RPL14 0.8 7.48 0.56 1.18e-11 Renal cell carcinoma; TGCT cis rs9611565 0.512 rs5758439 chr22:42131762 C/T cg06481639 chr22:41940642 POLR3H 0.7 6.1 0.48 1.24e-8 Vitiligo; TGCT cis rs11997175 0.574 rs872489 chr8:33646401 T/C ch.8.33884649F chr8:33765107 NA 0.28 4.53 0.38 1.35e-5 Body mass index; TGCT cis rs6748734 1.000 rs3936203 chr2:241834654 C/T cg04034577 chr2:241836375 C2orf54 0.4 6.32 0.49 4.22e-9 Urinary metabolites; TGCT cis rs875971 0.862 rs7798630 chr7:65771479 G/C cg11764359 chr7:65958608 NA -0.55 -5.0 -0.41 1.94e-6 Aortic root size; TGCT cis rs151997 0.962 rs26088 chr5:50172670 T/G cg06027927 chr5:50259733 NA 0.44 4.52 0.38 1.42e-5 Callous-unemotional behaviour; TGCT cis rs514406 0.505 rs374662 chr1:53164549 C/A cg24675658 chr1:53192096 ZYG11B -0.74 -8.3 -0.6 1.52e-13 Monocyte count; TGCT cis rs904251 0.828 rs1757178 chr6:37486310 C/T cg25019722 chr6:37503610 NA 0.51 6.84 0.52 3.24e-10 Cognitive performance; TGCT cis rs36051895 0.664 rs10117565 chr9:5094461 G/A cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs2677744 0.719 rs2106673 chr15:91452595 A/G cg23684204 chr15:91497937 RCCD1 0.36 5.17 0.42 9.11e-7 Attention deficit hyperactivity disorder; TGCT cis rs7572733 0.534 rs700670 chr2:198687284 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs13108904 0.870 rs2291199 chr4:1244267 A/G cg05665937 chr4:1216051 CTBP1 0.25 5.03 0.41 1.7e-6 Obesity-related traits; TGCT cis rs8072100 0.807 rs4561509 chr17:45781799 G/A cg08085267 chr17:45401833 C17orf57 -0.49 -5.67 -0.45 9.45e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs6690583 0.524 rs6680422 chr1:85451945 C/T cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs2836950 0.501 rs13047518 chr21:40707307 G/A cg22974920 chr21:40686053 BRWD1 -0.5 -4.46 -0.37 1.8e-5 Menarche (age at onset); TGCT cis rs6121246 0.909 rs6058450 chr20:30343911 G/A cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs1670533 1.000 rs2045066 chr4:1052401 C/T cg20887711 chr4:1340912 KIAA1530 0.63 4.92 0.4 2.7e-6 Recombination rate (females); TGCT cis rs2576037 0.583 rs8096263 chr18:44515216 C/T cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.68 -0.39 7.26e-6 Personality dimensions; TGCT cis rs4478037 0.822 rs9865342 chr3:33118631 G/A cg19404215 chr3:33155277 CRTAP 1.28 6.37 0.5 3.33e-9 Major depressive disorder; TGCT cis rs1729951 0.575 rs10935213 chr3:136693459 A/G cg21827317 chr3:136751795 NA 0.4 5.63 0.45 1.16e-7 Neuroticism; TGCT cis rs950169 0.922 rs4586394 chr15:84822385 G/A cg11189052 chr15:85197271 WDR73 -0.82 -6.5 -0.5 1.73e-9 Schizophrenia; TGCT cis rs740474 0.652 rs251022 chr5:140892643 T/C cg24137543 chr5:140893634 NA 0.46 4.57 0.38 1.16e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2742417 0.967 rs2742419 chr3:45731929 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.67 -0.45 9.39e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs16939607 0.822 rs2128019 chr8:78994159 G/T cg21244580 chr8:79934476 NA 0.49 5.38 0.43 3.64e-7 White blood cell count; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg27535305 chr1:53392650 SCP2 -0.25 -4.65 -0.38 8.53e-6 Monocyte count; TGCT cis rs12478296 1.000 rs55767645 chr2:242999350 G/A cg06360820 chr2:242988706 NA -0.76 -4.93 -0.41 2.55e-6 Obesity-related traits; TGCT cis rs2836974 0.568 rs452377 chr21:40537183 T/C cg06238570 chr21:40685208 BRWD1 0.8 9.11 0.63 1.74e-15 Cognitive function; TGCT cis rs7954584 0.635 rs7137218 chr12:122342877 G/T cg13699009 chr12:122356056 WDR66 0.28 6.26 0.49 5.63e-9 Mean corpuscular volume; TGCT cis rs2070488 1.000 rs36006749 chr3:38443312 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.66 0.66 8.43e-17 Electrocardiographic conduction measures; TGCT cis rs7017914 0.902 rs3098866 chr8:71916574 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.31 -0.43 4.8e-7 Bone mineral density; TGCT cis rs950169 0.656 rs11632395 chr15:85145793 C/A cg17173187 chr15:85201210 NMB 0.5 5.37 0.43 3.76e-7 Schizophrenia; TGCT cis rs73198271 0.751 rs617813 chr8:8635888 A/G cg06671706 chr8:8559999 CLDN23 -0.35 -4.56 -0.38 1.19e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs939658 0.805 rs8024813 chr15:79427260 A/G cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs6866344 0.697 rs61247551 chr5:178133503 G/A cg03877680 chr5:178157825 ZNF354A 0.75 6.1 0.48 1.25e-8 Neutrophil percentage of white cells; TGCT trans rs1496653 0.602 rs13071171 chr3:23585115 G/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs6933660 0.646 rs9397051 chr6:151778325 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.55 5.39 0.44 3.47e-7 Menarche (age at onset); TGCT cis rs539096 0.872 rs663618 chr1:44043105 T/C cg12908607 chr1:44402522 ARTN -0.5 -5.21 -0.42 7.49e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.836 rs1041440 chr21:40627325 C/T cg11890956 chr21:40555474 PSMG1 1.11 12.48 0.75 1.21e-23 Cognitive function; TGCT cis rs554111 0.593 rs9426660 chr1:21520449 A/G cg01072550 chr1:21505969 NA -0.37 -5.58 -0.45 1.45e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs6835098 0.646 rs10012395 chr4:174078772 A/G cg08422745 chr4:174089978 GALNT7 -0.77 -8.6 -0.61 2.87e-14 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs6582630 0.638 rs4882309 chr12:38448595 A/G cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs11118844 0.843 rs12403995 chr1:221921377 C/A cg04222084 chr1:221915650 DUSP10 -0.78 -5.42 -0.44 2.96e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs853679 0.546 rs200949 chr6:27835435 A/G cg01031101 chr6:28227091 NKAPL -0.49 -4.66 -0.39 8.09e-6 Depression; TGCT cis rs3820068 0.608 rs7552400 chr1:16035892 A/G cg05660106 chr1:15850417 CASP9 0.67 6.48 0.5 1.96e-9 Systolic blood pressure; TGCT cis rs1975974 0.574 rs59896566 chr17:21733621 C/T cg18423549 chr17:21743878 NA -0.61 -5.99 -0.47 2.14e-8 Psoriasis; TGCT cis rs4713118 0.621 rs10484403 chr6:28033523 A/G cg12963246 chr6:28129442 ZNF389 0.47 4.66 0.39 8.12e-6 Parkinson's disease; TGCT trans rs916888 0.773 rs199447 chr17:44812188 C/T cg07870213 chr5:140052090 DND1 0.65 7.75 0.57 2.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs1496653 0.602 rs13066741 chr3:23426332 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs6089829 0.962 rs4997812 chr20:61663153 T/G cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs4733781 0.933 rs9643252 chr8:131332667 G/A cg16277922 chr8:131349729 ASAP1 0.36 4.65 0.39 8.22e-6 Tuberculosis; TGCT cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs7666738 0.512 rs6532704 chr4:98777562 C/T cg17366294 chr4:99064904 C4orf37 0.52 5.59 0.45 1.4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs76878669 0.515 rs947978 chr11:66108660 C/T cg18002602 chr11:66138449 SLC29A2 0.53 6.45 0.5 2.23e-9 Educational attainment (years of education); TGCT trans rs4332037 0.851 rs1403175 chr7:1964357 A/T cg25206134 chr2:45395956 NA -1.1 -9.53 -0.65 1.75e-16 Bipolar disorder; TGCT trans rs1814175 0.791 rs9787917 chr11:49937281 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs2836974 0.931 rs2776309 chr21:40715791 A/G cg17971929 chr21:40555470 PSMG1 0.91 7.93 0.58 1.07e-12 Cognitive function; TGCT cis rs9682041 0.825 rs6785326 chr3:170095145 T/C cg07589077 chr3:170072950 NA 0.31 4.7 0.39 6.94e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.753 rs2865957 chr4:99040725 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10927875 0.632 rs4661667 chr1:16162731 C/T cg14742211 chr1:16348397 CLCNKA -0.19 -4.68 -0.39 7.38e-6 Dilated cardiomyopathy; TGCT cis rs595982 0.726 rs607356 chr19:49371241 T/C cg21252483 chr19:49399788 TULP2 -0.31 -5.25 -0.43 6.47e-7 Red cell distribution width; TGCT cis rs9916302 0.706 rs12937013 chr17:37665571 G/A cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs858239 0.539 rs6949363 chr7:23192394 A/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs6882046 0.513 rs601942 chr5:88031820 T/C cg24804195 chr5:87968844 LOC645323 -0.59 -5.9 -0.47 3.31e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs1696756 0.638 rs1285274 chr17:77829907 G/A cg00646381 chr17:77835854 NA 0.44 6.6 0.51 1.06e-9 Glucocorticoid-induced osteonecrosis (age 10 years and older); TGCT cis rs68170813 0.559 rs79564258 chr7:107059803 C/A cg02696742 chr7:106810147 HBP1 -0.71 -5.9 -0.47 3.17e-8 Coronary artery disease; TGCT cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg20607798 chr8:58055168 NA 0.65 5.43 0.44 2.86e-7 Developmental language disorder (linguistic errors); TGCT cis rs12541335 0.639 rs4872468 chr8:22179844 G/C cg18135555 chr8:22132992 PIWIL2 0.3 6.21 0.49 7.5e-9 Hypertriglyceridemia; TGCT cis rs7618915 0.501 rs7622694 chr3:52663882 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs4642101 0.537 rs4997708 chr3:12839603 G/A cg05775895 chr3:12838266 CAND2 0.67 7.07 0.54 9.95e-11 QRS complex (12-leadsum); TGCT cis rs11190604 0.731 rs10883480 chr10:102163821 G/T cg23241863 chr10:102295624 HIF1AN -0.63 -4.82 -0.4 4.06e-6 Palmitoleic acid (16:1n-7) levels; TGCT trans rs916888 0.773 rs199535 chr17:44822662 A/G cg01341218 chr17:43662625 NA 1.08 8.78 0.62 1.12e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs231513 0.906 rs75508812 chr17:42003397 G/A cg26893861 chr17:41843967 DUSP3 0.73 5.12 0.42 1.12e-6 Cognitive function; TGCT cis rs7666738 0.830 rs4699580 chr4:98930673 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4478858 0.709 rs3766296 chr1:31820223 G/A cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs999943 0.846 rs9357162 chr6:33613344 G/A cg14003231 chr6:33640908 ITPR3 0.39 4.9 0.4 2.97e-6 Obesity (extreme); TGCT cis rs10510102 0.515 rs11200285 chr10:123713446 G/C cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs7267979 0.966 rs4815425 chr20:25398876 G/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs734999 0.588 rs78506337 chr1:2537095 G/A cg18854424 chr1:2615690 NA 0.45 5.03 0.41 1.66e-6 Ulcerative colitis; TGCT cis rs7081476 0.826 rs73596338 chr10:27259964 G/C cg08717896 chr10:27541913 LOC387646 -0.77 -4.76 -0.39 5.21e-6 Age-related diseases and mortality;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs7635838 0.785 rs2606738 chr3:11396562 T/C cg00170343 chr3:11313890 ATG7 0.64 6.21 0.49 7.42e-9 HDL cholesterol; TGCT cis rs67311347 1.000 rs73078162 chr3:40477109 G/A cg13683864 chr3:40499215 RPL14 -1.19 -13.31 -0.77 1.2e-25 Renal cell carcinoma; TGCT cis rs9527 0.830 rs10883790 chr10:104640955 A/C cg04362960 chr10:104952993 NT5C2 0.62 5.06 0.41 1.46e-6 Arsenic metabolism; TGCT cis rs9303401 0.659 rs62081315 chr17:56781468 T/C cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs10056811 0.510 rs10058171 chr5:74407991 C/T cg19683494 chr5:74908142 NA 0.63 5.06 0.41 1.49e-6 Coronary artery disease; TGCT cis rs939658 1.000 rs34286854 chr15:79454374 C/T cg17916960 chr15:79447300 NA -0.53 -8.63 -0.61 2.55e-14 Refractive error; TGCT cis rs13343954 0.778 rs10425586 chr19:33543337 G/T cg07624008 chr19:33672378 NA -0.28 -4.76 -0.39 5.22e-6 Colorectal cancer; TGCT cis rs2075371 1.000 rs1862047 chr7:133978078 G/C cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.68e-9 Mean platelet volume; TGCT cis rs7666738 0.830 rs1025203 chr4:99023073 G/A cg17366294 chr4:99064904 C4orf37 0.71 7.0 0.53 1.4e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs76878669 0.561 rs10750784 chr11:66110666 A/G cg18002602 chr11:66138449 SLC29A2 -0.51 -6.18 -0.49 8.42e-9 Educational attainment (years of education); TGCT cis rs9291683 0.588 rs35438220 chr4:9999398 C/T cg11266682 chr4:10021025 SLC2A9 0.66 9.23 0.64 9.39e-16 Bone mineral density; TGCT cis rs539096 0.540 rs37452 chr1:44297573 A/C cg12908607 chr1:44402522 ARTN -0.68 -8.12 -0.59 3.97e-13 Intelligence (multi-trait analysis); TGCT cis rs12257961 0.521 rs10796280 chr10:15375511 A/T cg10616319 chr10:15468812 NA -0.25 -4.56 -0.38 1.2e-5 Selective IgA deficiency; TGCT cis rs7666738 0.606 rs6839946 chr4:99076132 A/C cg17366294 chr4:99064904 C4orf37 0.61 5.73 0.46 7.22e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4478858 0.698 rs4949385 chr1:31793256 C/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.94 -0.41 2.47e-6 Alcohol dependence; TGCT cis rs3099143 1.000 rs7174048 chr15:77165416 T/C cg21673338 chr15:77095150 SCAPER 0.52 5.05 0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs7100689 0.753 rs1361458 chr10:82090339 A/T cg01528321 chr10:82214614 TSPAN14 0.8 7.92 0.58 1.15e-12 Post bronchodilator FEV1; TGCT cis rs610932 0.517 rs1285231 chr11:59979408 T/C cg18570331 chr11:60101691 MS4A6E 0.52 4.84 0.4 3.79e-6 Alzheimer's disease; TGCT cis rs11642862 1.000 rs112234000 chr16:30778808 G/A cg02466173 chr16:30829666 NA -0.39 -4.68 -0.39 7.24e-6 Tonsillectomy; TGCT cis rs2777491 1.000 rs11631770 chr15:41737059 T/C cg18705301 chr15:41695430 NDUFAF1 -0.72 -10.39 -0.68 1.39e-18 Ulcerative colitis; TGCT cis rs9357506 1.000 rs1345059 chr6:46307051 T/C cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs1552244 0.882 rs9757159 chr3:10039166 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs1729951 0.575 rs1654904 chr3:136681149 T/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs9300255 0.739 rs1402275 chr12:123750895 A/G cg00376283 chr12:123451042 ABCB9 0.74 5.71 0.46 7.74e-8 Neutrophil percentage of white cells; TGCT cis rs2239547 0.618 rs4687658 chr3:52860366 C/G cg11645453 chr3:52864694 ITIH4 0.34 5.67 0.45 9.34e-8 Schizophrenia; TGCT cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg16423285 chr20:60520624 NA 0.74 9.09 0.63 2.02e-15 Obesity-related traits; TGCT trans rs877282 0.898 rs36064821 chr10:760952 C/T cg22713356 chr15:30763199 NA 1.17 9.15 0.63 1.44e-15 Uric acid levels; TGCT trans rs797680 0.856 rs6688230 chr1:93641124 C/T cg27528825 chr2:159282178 CCDC148 -0.35 -6.85 -0.52 3.08e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1129187 0.702 rs2395943 chr6:42940673 A/G cg02353165 chr6:42928485 GNMT 0.8 7.13 0.54 7.19e-11 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1568889 0.592 rs7110074 chr11:28469325 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.68 5.25 0.43 6.39e-7 Bipolar disorder; TGCT cis rs9814567 1.000 rs7432268 chr3:134242051 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.11 -0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs506338 0.517 rs490192 chr11:64471369 C/T cg19395706 chr11:64412079 NRXN2 0.52 6.36 0.5 3.45e-9 Body mass index;Urate levels; TGCT cis rs57221529 0.825 rs7443550 chr5:578404 G/T cg20362242 chr5:692897 TPPP 0.48 4.51 0.38 1.47e-5 Lung disease severity in cystic fibrosis; TGCT cis rs7523273 0.597 rs2761437 chr1:207923081 A/G cg22525895 chr1:207977042 MIR29B2 0.44 6.5 0.5 1.79e-9 Schizophrenia; TGCT cis rs2230307 0.536 rs581097 chr1:100515920 C/T cg24955406 chr1:100503596 HIAT1 0.74 4.86 0.4 3.41e-6 Carotid intima media thickness; TGCT cis rs6500602 0.927 rs7200817 chr16:4480598 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.09 0.42 1.28e-6 Schizophrenia; TGCT cis rs910316 0.967 rs2024653 chr14:75595154 G/A cg11812906 chr14:75593930 NEK9 0.73 7.23 0.54 4.36e-11 Height; TGCT cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg17179660 chr6:151773299 C6orf211;RMND1 -0.51 -4.74 -0.39 5.67e-6 Menarche (age at onset); TGCT cis rs8103278 1.000 rs36091860 chr19:46312880 G/A cg11657440 chr19:46296263 DMWD -0.59 -5.72 -0.46 7.54e-8 Coronary artery disease; TGCT cis rs1008375 1.000 rs13106338 chr4:17676871 G/T cg18681998 chr4:17616180 MED28 -0.86 -8.78 -0.62 1.07e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1153858 1.000 rs1346268 chr15:45673029 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs2486012 1.000 rs2486007 chr1:44434613 A/G cg12908607 chr1:44402522 ARTN 0.71 5.8 0.46 5.08e-8 Intelligence (multi-trait analysis); TGCT cis rs734999 0.967 rs7544646 chr1:2496649 C/G cg18854424 chr1:2615690 NA 0.44 5.26 0.43 6.23e-7 Ulcerative colitis; TGCT cis rs597539 0.690 rs608810 chr11:68624118 G/C cg06112835 chr11:68658793 MRPL21 0.49 8.02 0.58 6.66e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6430585 0.527 rs12467569 chr2:136413847 T/C cg07169764 chr2:136633963 MCM6 0.96 8.46 0.61 6.24e-14 Corneal structure; TGCT cis rs6977660 0.714 rs10260866 chr7:19793151 T/C cg07541023 chr7:19748670 TWISTNB 0.85 4.84 0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs877282 0.898 rs12354872 chr10:763362 G/A cg17470449 chr10:769945 NA 0.36 5.17 0.42 9.01e-7 Uric acid levels; TGCT cis rs7829975 0.777 rs560544 chr8:8637429 G/A cg17143192 chr8:8559678 CLDN23 -0.46 -4.45 -0.37 1.88e-5 Mood instability; TGCT cis rs7726839 0.574 rs72705014 chr5:619815 C/G cg09021430 chr5:549028 NA -0.46 -6.07 -0.48 1.42e-8 Obesity-related traits; TGCT cis rs9611565 0.659 rs1810460 chr22:41927700 C/T cg03806693 chr22:41940476 POLR3H -1.11 -13.11 -0.76 3.63e-25 Vitiligo; TGCT cis rs7659604 0.539 rs11098646 chr4:122729301 T/C cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.23e-7 Type 2 diabetes; TGCT cis rs3096299 0.933 rs3096297 chr16:89453155 T/G cg06640241 chr16:89574553 SPG7 0.62 5.99 0.47 2.1e-8 Multiple myeloma (IgH translocation); TGCT cis rs7666738 0.830 rs62321587 chr4:98997958 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs910187 0.597 rs1883885 chr20:45795456 T/C cg27589058 chr20:45804311 EYA2 -0.37 -7.01 -0.53 1.37e-10 Migraine; TGCT cis rs6693567 0.565 rs10888584 chr1:150476406 C/G cg09579323 chr1:150459698 TARS2 0.53 4.63 0.38 9.01e-6 Migraine; TGCT cis rs7605378 0.528 rs1704191 chr2:200816393 C/A cg19045956 chr2:200819837 C2orf60;C2orf47 0.53 5.57 0.45 1.48e-7 Osteoporosis; TGCT cis rs3806843 0.771 rs2563334 chr5:140107065 C/G cg19875535 chr5:140030758 IK -0.37 -6.19 -0.49 7.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9291683 0.552 rs11736410 chr4:10017241 G/A cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Bone mineral density; TGCT cis rs7731657 0.537 rs72801738 chr5:130207637 A/G cg08523029 chr5:130500466 HINT1 -0.59 -4.9 -0.4 2.87e-6 Fasting plasma glucose; TGCT cis rs153916 0.643 rs466748 chr5:95010028 T/C cg26072123 chr5:95066710 RHOBTB3 -0.44 -4.63 -0.38 9.23e-6 Pulmonary function; TGCT cis rs7010267 0.596 rs12682278 chr8:120032328 C/T cg17171407 chr8:119960777 TNFRSF11B -0.26 -5.1 -0.42 1.21e-6 Total body bone mineral density (age 45-60); TGCT cis rs2070488 1.000 rs2268758 chr3:38514049 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.75 0.66 5e-17 Electrocardiographic conduction measures; TGCT cis rs7662987 0.517 rs2851286 chr4:100014976 A/G cg12011299 chr4:100065546 ADH4 -0.42 -5.0 -0.41 1.91e-6 Smoking initiation; TGCT cis rs2075165 0.901 rs7542798 chr1:156224304 A/G cg20302342 chr1:156215951 PAQR6 0.39 5.67 0.45 9.49e-8 Tonsillectomy; TGCT cis rs9611565 0.546 rs132793 chr22:42063681 A/G cg13695892 chr22:41940480 POLR3H 0.85 8.05 0.59 5.7e-13 Vitiligo; TGCT cis rs7940866 0.809 rs11222410 chr11:130833994 A/G cg05962950 chr11:130786565 SNX19 0.69 6.87 0.53 2.73e-10 Schizophrenia; TGCT cis rs7017914 0.967 rs6982406 chr8:71654608 T/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs17102423 0.755 rs12880781 chr14:65576257 C/T cg11161011 chr14:65562177 MAX -0.54 -7.49 -0.56 1.15e-11 Obesity-related traits; TGCT cis rs11677370 0.603 rs10171309 chr2:3851690 C/T cg17052675 chr2:3827356 NA -0.39 -6.74 -0.52 5.41e-10 Type 2 diabetes; TGCT cis rs7666738 0.512 rs6532704 chr4:98777562 C/T cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4595586 0.563 rs11169769 chr12:39233134 C/G cg13010199 chr12:38710504 ALG10B 0.6 4.72 0.39 6.26e-6 Morning vs. evening chronotype; TGCT cis rs17736589 0.789 rs62075626 chr17:76814400 A/G cg05761277 chr17:76356738 SOCS3 -0.54 -4.53 -0.38 1.36e-5 Ulcerative colitis; TGCT cis rs6724607 1.000 rs4853513 chr2:191479455 C/T cg21644426 chr2:191273491 MFSD6 -0.54 -5.22 -0.42 7.42e-7 Pulse pressure; TGCT cis rs3808502 0.563 rs12541800 chr8:11423072 A/G cg21775007 chr8:11205619 TDH 0.52 4.66 0.39 8.06e-6 Neuroticism; TGCT cis rs1580019 0.961 rs958217 chr7:32493417 A/G cg06627557 chr7:32535165 LSM5;AVL9 0.73 7.08 0.54 9.24e-11 Cognitive ability; TGCT cis rs12145833 0.538 rs10754798 chr1:243309958 A/G cg02356786 chr1:243265016 LOC731275 -0.56 -5.17 -0.42 9.04e-7 Obesity (early onset extreme); TGCT cis rs11626933 1.000 rs4559843 chr14:90747488 T/C cg14092571 chr14:90743983 NA -0.3 -6.05 -0.48 1.6e-8 Gut microbiota (bacterial taxa); TGCT cis rs6952808 0.564 rs55865401 chr7:2145720 G/C cg04267008 chr7:1944627 MAD1L1 -0.38 -5.03 -0.41 1.65e-6 Bipolar disorder and schizophrenia; TGCT cis rs1371867 1.000 rs1371867 chr8:101330209 A/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.64 -0.38 8.84e-6 Atrioventricular conduction; TGCT cis rs7772486 0.754 rs4896839 chr6:146019689 T/G cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7772486 0.875 rs7739418 chr6:146359188 G/A cg05347473 chr6:146136440 FBXO30 0.52 4.93 0.41 2.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7843479 1.000 rs17615788 chr8:21814739 C/T cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs9796 0.870 rs11855248 chr15:41276158 G/A cg18705301 chr15:41695430 NDUFAF1 -0.43 -5.66 -0.45 9.84e-8 Menopause (age at onset); TGCT cis rs12908161 0.960 rs34452033 chr15:85221993 A/G cg11189052 chr15:85197271 WDR73 0.75 6.3 0.49 4.8e-9 Schizophrenia; TGCT cis rs4076943 0.634 rs7111444 chr11:11269833 T/A cg21653586 chr11:10530636 NA 0.49 4.99 0.41 1.99e-6 Post bronchodilator FEV1; TGCT cis rs9682041 0.561 rs6790483 chr3:170154406 G/A cg11886554 chr3:170076028 SKIL 0.94 6.65 0.51 8.16e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs42648 0.819 rs2285399 chr7:89969878 A/G cg25739043 chr7:89950458 NA -0.67 -6.46 -0.5 2.11e-9 Homocysteine levels; TGCT cis rs62103177 0.564 rs1864529 chr18:77748975 G/A cg07235805 chr18:78004237 PARD6G -0.47 -4.53 -0.38 1.35e-5 Opioid sensitivity; TGCT cis rs453301 0.686 rs6748 chr8:8890802 C/T cg00184457 chr8:8946301 NA -0.26 -4.94 -0.41 2.45e-6 Joint mobility (Beighton score); TGCT cis rs2692947 0.566 rs11676901 chr2:96370571 A/C cg23100626 chr2:96804247 ASTL 0.42 5.07 0.41 1.41e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7020830 0.898 rs6476617 chr9:37200103 G/A cg14294708 chr9:37120828 ZCCHC7 1.17 16.61 0.83 2.5e-33 Schizophrenia; TGCT cis rs6087990 0.735 rs1003522 chr20:31368560 T/C cg13636640 chr20:31349939 DNMT3B 0.95 12.05 0.73 1.28e-22 Ulcerative colitis; TGCT cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT trans rs6089829 0.962 rs6011544 chr20:61658782 T/C cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs728996 0.561 rs1326559 chr6:51652335 A/G cg20180370 chr6:50691003 TFAP2D -0.49 -4.7 -0.39 6.71e-6 Weight loss (gastric bypass surgery); TGCT cis rs28595532 0.841 rs114123875 chr4:119733408 A/G cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs6087771 0.926 rs6058431 chr20:30297133 C/T cg10886678 chr20:30946050 ASXL1 -0.57 -4.86 -0.4 3.44e-6 Subcortical brain region volumes;Putamen volume; TGCT cis rs7178572 1.000 rs11633054 chr15:77747276 A/G cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs227917 1.000 rs227923 chr7:23655548 C/A cg12601843 chr7:23510954 IGF2BP3 0.58 4.6 0.38 1.01e-5 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs7666738 0.830 rs1365458 chr4:98950961 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.43 0.55 1.56e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs422249 0.547 rs102275 chr11:61557803 T/C cg20584555 chr11:61717780 BEST1 -0.23 -4.49 -0.37 1.6e-5 Trans fatty acid levels; TGCT cis rs9457247 1.000 rs404222 chr6:167402150 G/A cg25258033 chr6:167368657 RNASET2 0.19 4.51 0.38 1.5e-5 Crohn's disease; TGCT trans rs10802346 0.545 rs12134404 chr1:246372144 A/G cg13514129 chr1:39547527 MACF1 0.83 7.33 0.55 2.59e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs4819052 1.000 rs2838847 chr21:46670958 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.99 8.16 0.59 3.26e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8014204 0.736 rs2111705 chr14:75261641 G/A cg06637938 chr14:75390232 RPS6KL1 0.58 5.12 0.42 1.15e-6 Caffeine consumption; TGCT cis rs3947 1.000 rs1736084 chr8:11703657 C/T cg02840367 chr8:11660030 FDFT1 0.9 6.51 0.5 1.64e-9 Blood protein levels; TGCT cis rs9911578 1.000 rs12453049 chr17:56611372 C/T cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.851 rs4390625 chr17:37620347 A/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg16325326 chr1:53192061 ZYG11B -0.85 -11.97 -0.73 1.98e-22 Monocyte count; TGCT cis rs9296092 0.560 rs17627049 chr6:33537802 G/T cg13560919 chr6:33536144 NA -0.21 -4.78 -0.39 4.8e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7618915 0.547 rs11130314 chr3:52697082 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs1580019 0.563 rs764483 chr7:32578150 A/T cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.9 0.4 2.9e-6 Cognitive ability; TGCT cis rs2046867 0.628 rs62249880 chr3:72918940 C/T cg25664220 chr3:72788482 NA -0.43 -5.79 -0.46 5.35e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6076065 0.748 rs6048779 chr20:23374709 C/G cg11657817 chr20:23433608 CST11 0.31 5.47 0.44 2.42e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs8141529 0.732 rs3788409 chr22:29198151 T/G cg02153584 chr22:29168773 CCDC117 0.67 5.68 0.45 9.04e-8 Lymphocyte counts; TGCT cis rs7618915 0.547 rs62253733 chr3:52653414 A/G cg07507251 chr3:52567010 NT5DC2 0.46 6.68 0.51 7.37e-10 Bipolar disorder; TGCT cis rs6500602 0.592 rs4785966 chr16:4518754 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.44 -7.58 -0.56 7.14e-12 Schizophrenia; TGCT cis rs9910055 0.571 rs28897216 chr17:42240824 A/G cg13607699 chr17:42295918 UBTF 0.59 5.45 0.44 2.61e-7 Total body bone mineral density; TGCT cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs765787 0.530 rs11854294 chr15:45527996 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.75e-7 Uric acid levels; TGCT cis rs2354432 0.607 rs11579626 chr1:146741960 A/C cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs9916302 0.904 rs3744348 chr17:37417575 C/G cg15445000 chr17:37608096 MED1 0.33 4.84 0.4 3.8e-6 Glomerular filtration rate (creatinine); TGCT cis rs9467603 0.858 rs972087 chr6:25872579 A/G cg16898833 chr6:26189333 HIST1H4D 1.05 5.43 0.44 2.82e-7 Intelligence (multi-trait analysis); TGCT cis rs9650657 0.683 rs7836366 chr8:10585683 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.51 -0.38 1.46e-5 Neuroticism; TGCT cis rs10114408 0.959 rs1987334 chr9:96635909 G/C cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7666738 0.515 rs13118898 chr4:98792893 T/A cg17366294 chr4:99064904 C4orf37 0.61 5.69 0.46 8.47e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7246657 0.943 rs10422967 chr19:37850137 T/C cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs3784262 0.669 rs10851632 chr15:58242475 A/T cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.14 -0.48 1e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7904368 0.754 rs12269366 chr10:16850344 G/A cg14835575 chr10:16859367 RSU1 0.68 7.32 0.55 2.77e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs60871478 1.000 rs60871478 chr7:827325 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.5 4.86 0.4 3.54e-6 Cerebrospinal P-tau181p levels; TGCT cis rs2688608 0.592 rs11000760 chr10:75493734 G/A cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT trans rs4650994 0.544 rs2476560 chr1:178594919 A/G cg05059571 chr16:84539110 KIAA1609 0.52 10.37 0.68 1.56e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2898681 0.521 rs115874483 chr4:53728272 G/A cg00791764 chr4:53727839 RASL11B 0.54 4.58 0.38 1.1e-5 Optic nerve measurement (cup area); TGCT cis rs11785400 1.000 rs4518642 chr8:143737396 T/C cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs763014 0.865 rs4006748 chr16:632225 T/C cg00908189 chr16:619842 PIGQ 0.87 10.5 0.69 7.53e-19 Height; TGCT cis rs10791097 0.720 rs6590518 chr11:130733530 C/T cg05962950 chr11:130786565 SNX19 0.9 11.14 0.71 2.13e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4689388 0.890 rs4689398 chr4:6302199 C/T cg14416269 chr4:6271139 WFS1 0.41 5.51 0.44 1.98e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2404602 0.684 rs1011084 chr15:77007480 C/G cg22467129 chr15:76604101 ETFA 0.47 4.7 0.39 6.84e-6 Blood metabolite levels; TGCT cis rs317689 0.718 rs315130 chr12:69761444 T/C cg14784868 chr12:69753453 YEATS4 0.56 4.63 0.38 8.93e-6 Response to diuretic therapy; TGCT cis rs9291683 0.609 rs55959894 chr4:10026580 G/A cg00071950 chr4:10020882 SLC2A9 0.7 9.41 0.65 3.47e-16 Bone mineral density; TGCT cis rs78487399 0.710 rs75514072 chr2:43750224 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs28595532 0.841 rs114735834 chr4:119772722 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT trans rs7824557 0.545 rs2572380 chr8:11237477 A/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.12e-10 Retinal vascular caliber; TGCT cis rs12989701 0.877 rs7557280 chr2:127873161 T/A cg08168897 chr2:127865431 BIN1 0.53 5.77 0.46 6.05e-8 Alzheimer's disease (late onset); TGCT cis rs7914558 0.933 rs10883814 chr10:104737404 T/C cg05855489 chr10:104503620 C10orf26 0.51 4.53 0.38 1.39e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs11677416 1.000 rs72825514 chr2:113527706 G/T cg27083787 chr2:113543245 IL1A 0.17 4.46 0.37 1.83e-5 Response to antipsychotic treatment in schizophrenia (working memory); TGCT cis rs6754311 0.773 rs680428 chr2:136630757 A/G cg07169764 chr2:136633963 MCM6 -0.65 -6.06 -0.48 1.5e-8 Mosquito bite size; TGCT cis rs4975616 0.869 rs401681 chr5:1322087 C/T cg06550200 chr5:1325588 CLPTM1L -0.32 -5.0 -0.41 1.92e-6 Lung cancer; TGCT cis rs477895 1.000 rs12785488 chr11:64107521 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.7 5.35 0.43 4.17e-7 Mean platelet volume; TGCT cis rs9486719 1.000 rs11152951 chr6:96894135 C/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs896854 0.812 rs12546365 chr8:95911477 T/C cg09323728 chr8:95962352 TP53INP1 -0.49 -6.26 -0.49 5.8e-9 Type 2 diabetes; TGCT cis rs4699052 0.599 rs11938459 chr4:104233989 T/C cg16532752 chr4:104119610 CENPE -0.47 -4.56 -0.38 1.2e-5 Testicular germ cell tumor; TGCT cis rs2439831 0.681 rs2278858 chr15:43632755 G/T cg27015174 chr15:43622946 ADAL;LCMT2 0.9 5.82 0.46 4.77e-8 Lung cancer in ever smokers; TGCT cis rs9611565 0.512 rs132767 chr22:42009520 C/T cg13695892 chr22:41940480 POLR3H -0.8 -7.41 -0.55 1.71e-11 Vitiligo; TGCT trans rs8097348 0.593 rs9965002 chr18:1710504 G/A cg20681184 chr1:9750813 PIK3CD -0.43 -6.78 -0.52 4.33e-10 Exercise (leisure time); TGCT cis rs597539 0.617 rs686348 chr11:68636996 A/G cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1372520 0.567 rs2619349 chr4:90746646 G/T cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs597539 0.652 rs667989 chr11:68685776 T/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 7.37 0.55 2.06e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs72945132 0.882 rs72947012 chr11:70149472 G/A cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs6490294 0.583 rs4767296 chr12:112463366 T/C cg10833066 chr12:111807467 FAM109A 0.34 5.32 0.43 4.67e-7 Mean platelet volume; TGCT cis rs11122272 0.766 rs2739511 chr1:231526490 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.73 -7.29 -0.55 3.25e-11 Hemoglobin concentration; TGCT trans rs1005277 0.579 rs2474595 chr10:38426782 C/G cg27523141 chr10:43048294 ZNF37B -0.74 -8.46 -0.6 6.33e-14 Extrinsic epigenetic age acceleration; TGCT cis rs6089584 0.888 rs2181590 chr20:60622843 T/C cg16423285 chr20:60520624 NA -0.6 -6.41 -0.5 2.76e-9 Body mass index; TGCT cis rs114540395 0.925 rs77449307 chr10:103385599 A/C cg18276125 chr10:102749041 C10orf2 0.39 4.68 0.39 7.31e-6 Schizophrenia; TGCT cis rs8180040 1.000 rs8180040 chr3:47388947 A/T cg27129171 chr3:47204927 SETD2 0.7 8.63 0.61 2.53e-14 Colorectal cancer; TGCT cis rs7014346 0.767 rs10956366 chr8:128423491 G/A cg04263511 chr8:128962092 PVT1 -0.33 -4.71 -0.39 6.51e-6 Colorectal cancer; TGCT cis rs6831352 0.959 rs6532795 chr4:100042221 C/T cg12011299 chr4:100065546 ADH4 -0.42 -5.22 -0.42 7.16e-7 Alcohol dependence; TGCT cis rs713587 0.563 rs2384057 chr2:25100167 C/G cg01884057 chr2:25150051 NA 0.31 5.82 0.46 4.63e-8 Body mass index in non-asthmatics; TGCT cis rs9987353 0.544 rs2929469 chr8:9062656 T/G cg15556689 chr8:8085844 FLJ10661 0.54 5.13 0.42 1.1e-6 Recombination measurement; TGCT trans rs629535 0.773 rs655299 chr8:70074534 C/T cg21567404 chr3:27674614 NA 0.57 9.09 0.63 1.94e-15 Dupuytren's disease; TGCT cis rs10479542 0.806 rs4700836 chr5:178976393 A/G cg19626725 chr5:178986131 RUFY1 0.44 5.46 0.44 2.49e-7 Lung cancer; TGCT cis rs6964587 1.000 rs2282968 chr7:91580287 A/C cg17063962 chr7:91808500 NA -0.91 -9.88 -0.66 2.45e-17 Breast cancer; TGCT cis rs6840360 1.000 rs6839074 chr4:152603357 A/G cg17479576 chr4:152424074 FAM160A1 0.46 4.91 0.4 2.86e-6 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg17971929 chr21:40555470 PSMG1 0.98 9.51 0.65 1.95e-16 Cognitive function; TGCT cis rs7666738 0.830 rs28810677 chr4:99043193 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1865760 0.566 rs9467672 chr6:26083904 C/T cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg09904177 chr6:26538194 HMGN4 0.67 6.3 0.49 4.72e-9 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.966 rs11953833 chr5:140155123 T/A cg19875535 chr5:140030758 IK 0.36 6.17 0.48 8.74e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6752107 0.837 rs3792108 chr2:234184952 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.73 0.39 6.08e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs5750830 0.649 rs5750814 chr22:39797987 T/C cg02038168 chr22:39784481 NA -0.77 -6.65 -0.51 8.24e-10 Intelligence (multi-trait analysis); TGCT cis rs7666738 1.000 rs7666738 chr4:98968077 C/T cg17366294 chr4:99064904 C4orf37 0.76 6.93 0.53 2.03e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6733011 0.500 rs2280142 chr2:99434872 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.76 -0.39 5.33e-6 Bipolar disorder; TGCT cis rs7584330 0.695 rs77922291 chr2:238366317 T/G cg14458575 chr2:238380390 NA 0.51 8.14 0.59 3.53e-13 Prostate cancer; TGCT cis rs78461346 1.000 rs7504089 chr17:80484851 G/A cg15014069 chr17:80540666 FOXK2 0.4 5.03 0.41 1.65e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs7474896 0.583 rs10764144 chr10:37975732 G/C cg25427524 chr10:38739819 LOC399744 -0.31 -4.86 -0.4 3.44e-6 Obesity (extreme); TGCT cis rs16957091 0.647 rs8041432 chr15:43358759 C/T cg17935677 chr15:44119062 WDR76 0.54 4.83 0.4 3.88e-6 MGMT methylation in smokers; TGCT cis rs10883723 0.810 rs6584507 chr10:104254623 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2013441 1.000 rs3850783 chr17:20184501 C/T cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs12477438 0.765 rs7605734 chr2:99644068 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs9911578 0.839 rs1871751 chr17:57190368 A/G cg12560992 chr17:57184187 TRIM37 0.71 8.14 0.59 3.63e-13 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.569 rs10067754 chr5:93093110 T/A cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT cis rs2322633 0.515 rs1892474 chr6:80862349 G/A cg08355045 chr6:80787529 NA 0.33 4.89 0.4 3.06e-6 Height; TGCT cis rs644799 0.710 rs666398 chr11:95551136 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.48 0.61 5.55e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11122272 0.735 rs2790890 chr1:231514567 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs6964587 1.000 rs12533199 chr7:91757393 C/T cg22709100 chr7:91322751 NA 0.29 4.69 0.39 6.98e-6 Breast cancer; TGCT cis rs4665809 0.531 rs3892649 chr2:26457267 T/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs1577917 1.000 rs35760725 chr6:86648985 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs1018836 0.544 rs2063978 chr8:91459525 C/T cg16814680 chr8:91681699 NA -0.57 -5.56 -0.45 1.56e-7 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs77106637 1.000 rs11602858 chr11:72615069 C/G cg03713592 chr11:72463424 ARAP1 0.83 5.43 0.44 2.87e-7 Type 2 diabetes; TGCT cis rs1008375 0.966 rs10939758 chr4:17698255 C/T cg18681998 chr4:17616180 MED28 0.78 7.35 0.55 2.35e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4478037 0.558 rs57225144 chr3:33078354 G/C cg19404215 chr3:33155277 CRTAP 1.04 4.95 0.41 2.36e-6 Major depressive disorder; TGCT cis rs554111 0.614 rs10799661 chr1:21040079 C/A cg08890418 chr1:21044141 KIF17 0.47 4.62 0.38 9.65e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs1580019 0.563 rs764483 chr7:32578150 A/T cg06627557 chr7:32535165 LSM5;AVL9 1.17 15.04 0.8 9.9e-30 Cognitive ability; TGCT cis rs34638657 0.732 rs10514532 chr16:82200337 C/T cg09439754 chr16:82129088 HSD17B2 0.27 5.16 0.42 9.62e-7 Lung adenocarcinoma; TGCT cis rs1215050 0.791 rs165250 chr4:98696259 G/A cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg01585852 chr22:24235823 MIF -0.21 -4.6 -0.38 1.02e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs10953454 1.000 rs12705281 chr7:104475567 C/T cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.54e-10 Obesity; TGCT cis rs1580019 0.922 rs1466147 chr7:32486262 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.9 8.65 0.61 2.27e-14 Cognitive ability; TGCT cis rs11822910 0.737 rs2729389 chr11:57211646 A/G cg00522883 chr11:57194120 SLC43A3 -0.31 -4.74 -0.39 5.75e-6 Platelet distribution width; TGCT cis rs7582180 0.629 rs11686880 chr2:100956229 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.72 -0.39 6.18e-6 Intelligence (multi-trait analysis); TGCT cis rs765787 0.530 rs2554453 chr15:45522107 A/G cg24006582 chr15:45444508 DUOX1 -0.26 -5.64 -0.45 1.12e-7 Uric acid levels; TGCT cis rs4253772 0.591 rs9627324 chr22:46656511 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.55 4.46 0.37 1.84e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs6912958 0.559 rs6921504 chr6:88058972 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.71 0.46 7.78e-8 Monocyte percentage of white cells; TGCT cis rs4665809 0.793 rs6546715 chr2:26261520 G/A cg22920501 chr2:26401640 FAM59B -0.71 -6.1 -0.48 1.27e-8 Gut microbiome composition (summer); TGCT trans rs2727020 0.701 rs7949044 chr11:49597334 C/T cg03929089 chr4:120376271 NA -0.66 -7.12 -0.54 7.88e-11 Coronary artery disease; TGCT cis rs2346177 0.875 rs2346178 chr2:46647061 C/G cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.75 -0.39 5.45e-6 HDL cholesterol; TGCT cis rs72627509 0.951 rs17087335 chr4:57838583 G/T cg26694713 chr4:57773883 REST 0.75 6.45 0.5 2.32e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs79349575 0.756 rs2643361 chr17:46977462 T/G cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.04e-6 Type 2 diabetes; TGCT cis rs2847281 0.761 rs592390 chr18:12822314 T/C cg23598886 chr18:12777645 NA 0.38 4.61 0.38 9.83e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs61990749 0.597 rs11623088 chr14:78137735 G/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.67 -4.68 -0.39 7.39e-6 Fibroblast growth factor basic levels; TGCT cis rs514406 0.584 rs11205997 chr1:53195271 G/C cg01802117 chr1:53393560 SCP2 0.42 4.92 0.4 2.69e-6 Monocyte count; TGCT cis rs11716531 0.537 rs7626646 chr3:27268316 G/T cg02860705 chr3:27208620 NA 0.4 6.03 0.48 1.76e-8 Diastolic blood pressure; TGCT cis rs910316 0.591 rs7157158 chr14:75457238 A/G cg11812906 chr14:75593930 NEK9 0.58 5.56 0.45 1.6e-7 Height; TGCT cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1799949 1.000 rs8176233 chr17:41219804 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.1 0.42 1.24e-6 Menopause (age at onset); TGCT cis rs2201728 0.967 rs12507573 chr4:100226324 A/C cg07219303 chr4:100140905 ADH6 0.32 4.56 0.38 1.22e-5 Cardiac Troponin-T levels; TGCT cis rs2153535 0.580 rs4960433 chr6:8523697 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.07 0.41 1.4e-6 Motion sickness; TGCT cis rs6912958 0.728 rs6923230 chr6:88213949 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs265548 0.608 rs265544 chr19:17903479 G/C cg16744531 chr19:17905626 B3GNT3 0.4 4.92 0.4 2.65e-6 Tumor biomarkers; TGCT cis rs2836974 0.863 rs8132333 chr21:40527900 A/G cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs10484885 0.887 rs17707738 chr6:90602735 G/A cg13799429 chr6:90582589 CASP8AP2 -0.43 -4.46 -0.37 1.8e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs17376456 0.825 rs12153021 chr5:93073913 A/G cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs12549902 0.966 rs4737000 chr8:41509727 A/C cg00088007 chr8:41504566 NKX6-3 0.34 5.38 0.43 3.59e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs4077515 0.839 rs3812570 chr9:139275204 A/C cg13741927 chr9:139327495 INPP5E -0.19 -4.59 -0.38 1.05e-5 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT trans rs6089829 0.925 rs6122087 chr20:61664553 T/C cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2721195 0.743 rs2306386 chr8:145742879 T/C cg15320075 chr8:145703422 NA 0.65 6.33 0.49 4.07e-9 Age at first birth; TGCT cis rs597539 0.617 rs672853 chr11:68636362 G/A cg04772025 chr11:68637568 NA 0.6 6.78 0.52 4.32e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9926296 0.565 rs8055825 chr16:89832848 C/T cg27121462 chr16:89883253 FANCA 0.77 8.39 0.6 8.98e-14 Vitiligo; TGCT cis rs7582180 0.629 rs2164847 chr2:100958715 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs739401 0.611 rs12284275 chr11:3024384 T/C cg05729581 chr11:3078854 CARS -0.52 -4.71 -0.39 6.44e-6 Longevity; TGCT cis rs6896969 0.510 rs6880419 chr5:40428913 C/T cg01087697 chr5:40835557 RPL37 0.56 5.04 0.41 1.62e-6 Multiple sclerosis; TGCT cis rs9527 0.615 rs10883804 chr10:104706520 G/A cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs7818382 1.000 rs7818382 chr8:96054000 C/T cg13393036 chr8:95962371 TP53INP1 -0.43 -4.85 -0.4 3.7e-6 Alzheimer's disease (late onset); TGCT cis rs11112613 0.762 rs17037312 chr12:105950085 C/T cg03607813 chr12:105948248 NA 0.52 6.0 0.47 2.03e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg23708337 chr7:1209742 NA 0.56 5.1 0.42 1.25e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9549367 0.662 rs3818334 chr13:113825174 C/G cg18105134 chr13:113819100 PROZ -0.47 -8.14 -0.59 3.6e-13 Platelet distribution width; TGCT cis rs7513165 0.935 rs12097666 chr1:204162212 A/G cg04791601 chr1:204159016 NA 0.26 5.14 0.42 1.04e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs4478858 0.735 rs6679360 chr1:31817936 G/T cg07478791 chr1:31886160 SERINC2 -0.47 -4.54 -0.38 1.32e-5 Alcohol dependence; TGCT cis rs12762955 0.507 rs7095853 chr10:1040798 T/C cg26597838 chr10:835615 NA -0.47 -6.26 -0.49 5.7e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs2303745 0.589 rs11086065 chr19:17395003 A/G cg02221750 chr19:17393354 ANKLE1 -0.48 -6.28 -0.49 5.17e-9 Systemic lupus erythematosus; TGCT cis rs600231 0.683 rs588298 chr11:65253574 A/G cg17120908 chr11:65337727 SSSCA1 -0.56 -5.05 -0.41 1.54e-6 Bone mineral density; TGCT cis rs9393777 0.778 rs77666565 chr6:26851415 G/A cg16898833 chr6:26189333 HIST1H4D 1.13 5.55 0.45 1.65e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 1.000 rs7533888 chr1:76160449 A/C cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs986417 0.901 rs1884095 chr14:61017024 C/G cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs10504229 0.906 rs116341227 chr8:58190532 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.861 rs60346509 chr8:58196050 G/T cg24829409 chr8:58192753 C8orf71 -0.55 -4.77 -0.39 5.18e-6 Developmental language disorder (linguistic errors); TGCT cis rs9788682 1.000 rs57064725 chr15:78833036 C/A cg06917634 chr15:78832804 PSMA4 -0.7 -4.86 -0.4 3.47e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs35146811 0.735 rs6465766 chr7:99785671 A/G cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs208515 0.525 rs12191500 chr6:66668681 A/G cg07460842 chr6:66804631 NA 0.85 8.73 0.62 1.41e-14 Exhaled nitric oxide levels; TGCT cis rs6088590 0.931 rs6088617 chr20:33408036 G/A cg06115741 chr20:33292138 TP53INP2 0.65 5.43 0.44 2.82e-7 Coronary artery disease; TGCT cis rs17221829 0.614 rs2388202 chr11:89374231 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs1775715 0.651 rs2808033 chr10:32194127 A/T cg14930904 chr10:32216787 ARHGAP12 0.53 5.03 0.41 1.66e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg20887711 chr4:1340912 KIAA1530 0.78 6.53 0.51 1.51e-9 Longevity; TGCT cis rs68170813 0.559 rs3779498 chr7:106923158 C/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs3091242 0.967 rs3093614 chr1:25677844 T/A cg00786635 chr1:25594202 NA -0.53 -5.35 -0.43 4.08e-7 Erythrocyte sedimentation rate; TGCT cis rs9467773 1.000 rs9467779 chr6:26536687 A/T cg15659132 chr6:26577336 NA -0.83 -11.51 -0.72 2.61e-21 Intelligence (multi-trait analysis); TGCT cis rs35785195 0.593 rs35746281 chr12:114236586 C/T cg11070030 chr12:114232702 NA 0.26 4.45 0.37 1.87e-5 Daytime sleep phenotypes; TGCT cis rs1075232 0.826 rs12437800 chr15:31671432 A/G cg01030201 chr15:31746330 NA -1.01 -5.26 -0.43 6.07e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs7296418 0.961 rs1727307 chr12:123575742 A/G cg00376283 chr12:123451042 ABCB9 0.82 7.08 0.54 9.57e-11 Platelet count; TGCT cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.73 6.7 0.52 6.4e-10 Prudent dietary pattern; TGCT cis rs6901004 0.933 rs12208141 chr6:111572138 A/G cg15721981 chr6:111408429 SLC16A10 -0.52 -4.48 -0.37 1.66e-5 Blood metabolite levels; TGCT cis rs7091068 0.671 rs1764322 chr10:95406276 T/G cg20715218 chr10:95462985 C10orf4 -0.54 -5.12 -0.42 1.11e-6 Urinary tract infection frequency; TGCT trans rs10435719 0.902 rs7459983 chr8:11807221 T/C cg15556689 chr8:8085844 FLJ10661 0.79 7.5 0.56 1.09e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs67478160 0.643 rs11626377 chr14:104234357 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.57 -0.51 1.25e-9 Schizophrenia; TGCT cis rs2456568 0.741 rs2102332 chr11:93635281 G/T cg14065697 chr11:93583672 C11orf90 -0.37 -4.63 -0.38 9.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7681440 0.874 rs1372525 chr4:90776165 G/A cg14346243 chr4:90757452 SNCA -0.56 -5.47 -0.44 2.41e-7 Dementia with Lewy bodies; TGCT trans rs916888 0.610 rs199529 chr17:44837217 A/C cg07870213 chr5:140052090 DND1 0.59 7.11 0.54 8.14e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs208520 1.000 rs12199876 chr6:66989469 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs2836950 0.565 rs2836943 chr21:40592611 C/T cg11644478 chr21:40555479 PSMG1 -0.54 -5.1 -0.42 1.25e-6 Menarche (age at onset); TGCT trans rs561341 0.609 rs7214626 chr17:30190989 G/A cg20587970 chr11:113659929 NA 0.67 8.22 0.59 2.35e-13 Hip circumference adjusted for BMI; TGCT cis rs478304 0.651 rs4014195 chr11:65506822 C/G cg17480646 chr11:65405466 SIPA1 0.55 6.69 0.51 7.02e-10 Acne (severe); TGCT cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.47 -0.37 1.74e-5 Menarche (age at onset); TGCT cis rs8037137 0.571 rs3743445 chr15:91561182 C/T cg23684204 chr15:91497937 RCCD1 0.4 4.5 0.37 1.57e-5 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs317865 0.737 rs73234648 chr4:16193602 T/C cg04764131 chr4:16228633 TAPT1;FLJ39653 0.78 5.11 0.42 1.18e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs7618915 0.524 rs2028216 chr3:52680823 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs4455778 0.735 rs10250566 chr7:49020113 C/A cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs7647973 1.000 rs8897 chr3:49460407 A/G cg05785598 chr3:49045655 WDR6 0.36 4.52 0.38 1.45e-5 Menarche (age at onset); TGCT cis rs10876993 0.855 rs1689604 chr12:58048304 T/C cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs700651 0.789 rs882954 chr2:198907444 A/G cg00792783 chr2:198669748 PLCL1 0.61 5.31 0.43 4.98e-7 Intracranial aneurysm; TGCT cis rs4788570 0.578 rs7204992 chr16:71658444 G/A cg06353428 chr16:71660113 MARVELD3 1.56 12.61 0.75 5.63e-24 Intelligence (multi-trait analysis); TGCT cis rs8051431 0.876 rs7185190 chr16:72019164 T/C cg06353428 chr16:71660113 MARVELD3 0.57 4.54 0.38 1.31e-5 LDL cholesterol levels; TGCT cis rs1008375 0.863 rs7680984 chr4:17600884 A/G cg10189774 chr4:17578691 LAP3 0.74 6.19 0.49 8.18e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4843185 0.637 rs4143866 chr16:85716366 A/G cg06784122 chr16:85688175 KIAA0182 0.27 4.51 0.38 1.46e-5 Platelet distribution width; TGCT cis rs1215050 0.740 rs1214997 chr4:99041533 A/T cg17366294 chr4:99064904 C4orf37 0.58 6.17 0.48 8.78e-9 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs7618501 1.000 rs11130221 chr3:49819102 C/G cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.559 rs2023892 chr7:106847686 C/T cg02696742 chr7:106810147 HBP1 0.68 5.74 0.46 7e-8 Coronary artery disease; TGCT cis rs6879260 1.000 rs7706951 chr5:179733407 C/T cg02891314 chr5:179741120 GFPT2 -0.41 -7.16 -0.54 6.21e-11 Height; TGCT cis rs2797160 1.000 rs2747717 chr6:126008435 A/G cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs7714584 1.000 rs7709650 chr5:150246685 C/T cg22134413 chr5:150180641 NA 0.93 6.99 0.53 1.52e-10 Crohn's disease; TGCT cis rs9467711 1.000 rs6939799 chr6:26328366 G/A cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7659604 0.537 rs6815973 chr4:122663430 A/T cg19748678 chr4:122722346 EXOSC9 -0.76 -6.82 -0.52 3.48e-10 Type 2 diabetes; TGCT cis rs7615952 0.736 rs9862893 chr3:125686974 A/G cg05084668 chr3:125655381 ALG1L -0.81 -5.69 -0.46 8.63e-8 Blood pressure (smoking interaction); TGCT cis rs4845570 0.920 rs11810571 chr1:151762308 C/G cg07092448 chr1:151763213 TDRKH 1.11 9.43 0.65 3.09e-16 Coronary artery disease; TGCT cis rs62103177 0.733 rs62103232 chr18:77635553 G/A cg12964065 chr18:77638022 KCNG2 0.38 4.8 0.4 4.4e-6 Opioid sensitivity; TGCT cis rs28595532 0.920 rs114938162 chr4:119756407 T/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs1018836 0.923 rs1858674 chr8:91580665 G/T cg16814680 chr8:91681699 NA -0.89 -9.58 -0.65 1.3e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.839 rs6901039 chr6:26000885 A/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.54 -4.62 -0.38 9.47e-6 Intelligence (multi-trait analysis); TGCT cis rs8103278 1.000 rs1548029 chr19:46309203 A/C cg14061069 chr19:46274453 DMPK -0.42 -5.82 -0.46 4.68e-8 Coronary artery disease; TGCT cis rs752010 0.619 rs6702659 chr1:42112236 T/C cg06885757 chr1:42089581 HIVEP3 0.28 5.02 0.41 1.78e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs4665809 0.549 rs17527979 chr2:26428132 A/G cg22920501 chr2:26401640 FAM59B -0.79 -5.33 -0.43 4.49e-7 Gut microbiome composition (summer); TGCT cis rs13242816 1.000 rs34936262 chr7:116160022 G/A cg16553024 chr7:116138462 CAV2 -0.45 -5.27 -0.43 5.81e-7 P wave duration; TGCT cis rs477895 0.713 rs12787852 chr11:63954648 G/A cg04317338 chr11:64019027 PLCB3 0.79 6.5 0.5 1.77e-9 Mean platelet volume; TGCT cis rs2456568 0.802 rs8181567 chr11:93637209 C/T cg16099599 chr11:93583650 C11orf90 -0.4 -5.12 -0.42 1.13e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg08645402 chr16:4508243 NA 0.2 5.01 0.41 1.86e-6 Schizophrenia; TGCT cis rs614226 1.000 rs541126 chr12:120972396 C/T cg10072921 chr12:121022843 NA 0.44 4.74 0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs11648796 0.721 rs743987 chr16:769566 C/G cg00908189 chr16:619842 PIGQ 0.8 6.33 0.49 4.04e-9 Height; TGCT cis rs1059312 0.932 rs4760593 chr12:129287220 A/G cg09035930 chr12:129282057 SLC15A4 0.58 11.18 0.71 1.67e-20 Systemic lupus erythematosus; TGCT cis rs67478160 0.643 rs4900600 chr14:104291839 A/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg26531700 chr6:26746687 NA -0.54 -4.87 -0.4 3.36e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs17826219 0.706 rs8071236 chr17:29100002 T/C cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Body mass index; TGCT cis rs66569888 0.507 rs17032699 chr2:106886471 A/G cg15412446 chr2:106886593 NA -0.53 -6.76 -0.52 4.9e-10 Facial morphology (factor 23); TGCT cis rs8077577 0.945 rs62073611 chr17:18071961 C/G cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs17826219 0.714 rs11650821 chr17:28968150 T/C cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Body mass index; TGCT cis rs4843747 0.671 rs28465438 chr16:88103714 G/A cg06915872 chr16:87998081 BANP -0.3 -4.61 -0.38 9.69e-6 Menopause (age at onset); TGCT cis rs6558530 0.666 rs6558523 chr8:1702504 T/C cg09410841 chr8:1729607 CLN8 0.71 6.43 0.5 2.56e-9 Systolic blood pressure; TGCT cis rs2288278 0.580 rs11652746 chr17:46592811 A/G cg25032089 chr17:46643351 HOXB3 -0.42 -5.0 -0.41 1.87e-6 Hand grip strength; TGCT cis rs7824557 0.688 rs2572397 chr8:11176403 G/A cg21775007 chr8:11205619 TDH 0.56 5.14 0.42 1.05e-6 Retinal vascular caliber; TGCT cis rs801193 1.000 rs7782320 chr7:66177098 C/T cg18876405 chr7:65276391 NA 0.33 5.05 0.41 1.55e-6 Aortic root size; TGCT cis rs2243480 0.901 rs58207111 chr7:65486723 C/T cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs10489525 0.599 rs7516121 chr1:115604317 A/G cg12756093 chr1:115239321 AMPD1 -0.41 -5.51 -0.44 1.96e-7 Autism; TGCT cis rs875971 0.508 rs6947808 chr7:66045082 A/G cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs7599312 0.534 rs2371615 chr2:213405660 G/T cg16329650 chr2:213403929 ERBB4 1.06 16.53 0.83 3.82e-33 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3858526 0.959 rs10838901 chr11:5959128 G/A cg05234568 chr11:5960015 NA -0.45 -4.54 -0.38 1.3e-5 DNA methylation (variation); TGCT cis rs4366490 1.000 rs7948969 chr11:62907048 A/C cg21002970 chr11:62369079 MTA2 0.87 4.69 0.39 6.98e-6 Conotruncal heart defects; TGCT cis rs2594989 0.943 rs1391903 chr3:11423271 C/G cg00170343 chr3:11313890 ATG7 -0.67 -4.99 -0.41 2.01e-6 Circulating chemerin levels; TGCT cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs11098499 0.954 rs10031483 chr4:120422636 T/C cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs9467773 0.549 rs9467805 chr6:26583366 C/T cg26531700 chr6:26746687 NA 0.5 4.74 0.39 5.69e-6 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs1577468 chr6:8444266 C/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs79349575 0.811 rs80032154 chr17:47014992 C/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.5 -0.37 1.53e-5 Type 2 diabetes; TGCT cis rs1372520 0.577 rs2737028 chr4:90717016 A/G cg14346243 chr4:90757452 SNCA -0.68 -5.58 -0.45 1.43e-7 Neuroticism; TGCT trans rs2688608 0.698 rs2633323 chr10:75694826 G/A cg13918328 chr10:52500089 ASAH2B 0.68 6.89 0.53 2.56e-10 Inflammatory bowel disease; TGCT cis rs17152411 0.895 rs11245419 chr10:126586392 A/T cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs9549260 0.564 rs6563844 chr13:41298190 T/C cg21288729 chr13:41239152 FOXO1 0.91 8.35 0.6 1.12e-13 Red blood cell count; TGCT cis rs561341 0.663 rs72821936 chr17:30224068 C/G cg13647721 chr17:30228624 UTP6 0.6 5.32 0.43 4.72e-7 Hip circumference adjusted for BMI; TGCT cis rs10782582 0.569 rs1770892 chr1:76389359 T/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.55 4.76 0.39 5.28e-6 Daytime sleep phenotypes; TGCT cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs1532993 0.518 rs3974914 chr4:98605767 G/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs13326165 0.760 rs34762015 chr3:52366044 G/A cg27565382 chr3:53032988 SFMBT1 0.37 4.89 0.4 3.1e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs698813 0.674 rs7590224 chr2:44501209 T/G cg00619915 chr2:44497795 NA -0.22 -5.06 -0.41 1.48e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs72717009 0.825 rs10494360 chr1:161475750 G/A cg23840854 chr1:161414152 NA -0.98 -5.87 -0.47 3.79e-8 Rheumatoid arthritis; TGCT trans rs916888 0.773 rs169201 chr17:44790203 A/G cg22968622 chr17:43663579 NA 1.29 11.02 0.7 4.06e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7833790 0.963 rs6473312 chr8:82732515 C/A cg17211192 chr8:82754475 SNX16 -1.06 -8.63 -0.61 2.54e-14 Diastolic blood pressure; TGCT cis rs2075371 0.830 rs2077671 chr7:133951204 C/T cg11752832 chr7:134001865 SLC35B4 0.68 5.89 0.47 3.32e-8 Mean platelet volume; TGCT cis rs2239785 0.959 rs136159 chr22:36657023 T/C cg15716373 chr22:36655542 APOL1 -0.42 -4.85 -0.4 3.59e-6 Glomerulosclerosis; TGCT cis rs10782582 0.609 rs2029682 chr1:76341619 T/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs1008375 1.000 rs2315560 chr4:17677305 C/G cg18681998 chr4:17616180 MED28 0.89 10.29 0.68 2.47e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs362272 0.505 rs13104157 chr4:3366950 T/C cg18352616 chr4:3374830 RGS12 0.26 5.27 0.43 5.79e-7 Serum sulfate level; TGCT cis rs6490294 0.904 rs9630276 chr12:112404838 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.69e-8 Mean platelet volume; TGCT cis rs35146811 0.735 rs1727133 chr7:99812870 C/T cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs2153535 0.601 rs718504 chr6:8527512 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs4466137 0.953 rs6869030 chr5:83007311 C/T cg16102102 chr5:83017553 HAPLN1 -1.11 -11.15 -0.71 1.97e-20 Prostate cancer; TGCT cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg18876405 chr7:65276391 NA 0.36 5.7 0.46 8.31e-8 Aortic root size; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs9929218 0.551 rs3785134 chr16:68728938 C/T cg01251360 chr16:68772225 CDH1 -0.27 -5.16 -0.42 9.67e-7 Colorectal cancer; TGCT cis rs9894429 1.000 rs7223613 chr17:79574803 C/T cg21028142 chr17:79581711 NPLOC4 -0.29 -6.81 -0.52 3.83e-10 Eye color traits; TGCT cis rs7552404 0.691 rs5745449 chr1:76344711 A/T cg22875332 chr1:76189707 ACADM -0.68 -7.11 -0.54 7.96e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg00684032 chr4:1343700 KIAA1530 -0.22 -4.71 -0.39 6.57e-6 Obesity-related traits; TGCT cis rs72781680 0.752 rs72796116 chr2:23913769 C/T cg08917208 chr2:24149416 ATAD2B 1.0 5.79 0.46 5.41e-8 Lymphocyte counts; TGCT cis rs1552244 0.515 rs111560858 chr3:10166845 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs2288073 0.965 rs10173173 chr2:24415461 G/T cg02683114 chr2:24398427 C2orf84 0.25 5.67 0.45 9.72e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs6921919 0.515 rs1558205 chr6:28382262 A/C cg13525197 chr6:28411240 ZSCAN23 0.46 4.44 0.37 1.95e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs77972916 0.609 rs72790903 chr2:43561985 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.46 -0.37 1.78e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs6684514 1.000 rs12118238 chr1:156235221 G/A cg20302342 chr1:156215951 PAQR6 0.35 4.64 0.38 8.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6964587 0.900 rs6465352 chr7:91775117 A/G cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.33e-6 Breast cancer; TGCT cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs7800443 chr7:106910723 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs346785 0.692 rs2279053 chr17:74287389 C/T cg09812376 chr17:74270190 QRICH2 0.37 5.68 0.45 9.02e-8 White matter hyperintensities in ischemic stroke; TGCT cis rs6967414 0.792 rs6954012 chr7:6755724 A/C cg09896999 chr7:6746977 ZNF12 -0.56 -6.34 -0.49 3.83e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs9837602 0.529 rs793459 chr3:99520591 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.71 0.52 6.1e-10 Breast cancer; TGCT cis rs422249 0.547 rs174533 chr11:61549025 G/A cg01500311 chr11:61656094 FADS3 -0.34 -5.63 -0.45 1.16e-7 Trans fatty acid levels; TGCT cis rs2050392 0.517 rs7096279 chr10:30759608 C/T cg18806716 chr10:30721971 MAP3K8 -0.46 -5.43 -0.44 2.79e-7 Inflammatory bowel disease; TGCT cis rs2832077 0.527 rs2776210 chr21:30268558 A/G cg24692254 chr21:30365293 RNF160 0.62 5.48 0.44 2.26e-7 Cognitive test performance; TGCT cis rs7666738 0.791 rs34152299 chr4:98929862 G/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6951245 1.000 rs28399710 chr7:1070631 G/T cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7940866 0.774 rs10894292 chr11:130820757 C/T cg05962950 chr11:130786565 SNX19 0.68 6.75 0.52 5.03e-10 Schizophrenia; TGCT cis rs7172809 0.573 rs78481361 chr15:77654784 C/T cg22256960 chr15:77711686 NA -0.51 -4.81 -0.4 4.29e-6 Glucose homeostasis traits; TGCT cis rs6952808 0.500 rs3778996 chr7:2177190 G/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.04 -0.48 1.63e-8 Bipolar disorder and schizophrenia; TGCT cis rs9916302 0.904 rs8068427 chr17:37511517 G/A cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs524281 0.692 rs2452681 chr11:65814842 G/A cg00563793 chr11:65837595 PACS1 -0.54 -4.92 -0.4 2.69e-6 Electroencephalogram traits; TGCT cis rs6426558 0.502 rs2813970 chr1:227410637 C/T cg10327440 chr1:227177885 CDC42BPA 0.58 6.52 0.51 1.62e-9 Neutrophil percentage of white cells; TGCT cis rs7267979 1.000 rs7020 chr20:25278600 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7781977 0.782 rs9886239 chr7:50336551 A/C cg01139861 chr7:50343298 IKZF1 0.52 5.75 0.46 6.62e-8 IgG glycosylation; TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg17178900 chr1:205818956 PM20D1 0.56 7.03 0.53 1.2e-10 Menarche (age at onset); TGCT cis rs2836950 0.545 rs2297256 chr21:40558421 C/T cg11644478 chr21:40555479 PSMG1 -0.52 -4.9 -0.4 2.98e-6 Menarche (age at onset); TGCT cis rs2235642 0.821 rs2281234 chr16:1602938 A/G cg07341220 chr16:1583899 IFT140;TMEM204 -0.29 -4.56 -0.38 1.23e-5 Coronary artery disease; TGCT cis rs10782582 0.609 rs76260657 chr1:76338017 C/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg20607798 chr8:58055168 NA 0.49 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs11676855 0.924 rs11680626 chr2:235927511 A/T cg14917874 chr2:235941519 SH3BP4 -0.23 -5.02 -0.41 1.75e-6 Dialysis-related mortality; TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg26338869 chr17:61819248 STRADA -0.55 -5.02 -0.41 1.73e-6 Prudent dietary pattern; TGCT cis rs854765 1.000 rs854765 chr17:18012730 T/C cg09796270 chr17:17721594 SREBF1 -0.27 -5.26 -0.43 6.14e-7 Total body bone mineral density; TGCT cis rs367943 0.966 rs455435 chr5:112799412 T/C cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs4478037 0.558 rs56106158 chr3:33081833 A/G cg19404215 chr3:33155277 CRTAP 1.09 5.31 0.43 4.86e-7 Major depressive disorder; TGCT cis rs694739 1.000 rs1783521 chr11:64106291 T/C cg23796481 chr11:64053134 BAD;GPR137 0.68 7.11 0.54 8.07e-11 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs10484885 0.752 rs72921948 chr6:90582560 T/C cg13799429 chr6:90582589 CASP8AP2 -0.55 -6.49 -0.5 1.87e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs12681287 0.640 rs13252046 chr8:87477751 G/T cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs2964802 0.505 rs6865234 chr5:10829742 C/A cg14521931 chr5:10832172 NA -0.26 -4.46 -0.37 1.78e-5 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs2594989 0.837 rs7642031 chr3:11453754 G/A cg00170343 chr3:11313890 ATG7 0.72 5.37 0.43 3.8e-7 Circulating chemerin levels; TGCT cis rs3772130 0.962 rs9839617 chr3:121516577 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs713587 0.713 rs4665276 chr2:25213333 C/T cg01884057 chr2:25150051 NA -0.38 -7.82 -0.57 1.95e-12 Body mass index in non-asthmatics; TGCT cis rs62064224 0.765 rs62065463 chr17:30732405 G/T cg18200150 chr17:30822561 MYO1D 0.58 7.84 0.58 1.73e-12 Schizophrenia; TGCT cis rs11249608 0.548 rs17078988 chr5:178459283 A/G cg01312482 chr5:178451176 ZNF879 -0.47 -4.68 -0.39 7.41e-6 Pubertal anthropometrics; TGCT cis rs9985766 1.000 rs28374205 chr4:150997822 A/G cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs78487399 0.808 rs10169346 chr2:43741105 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs17376456 0.935 rs13156002 chr5:93508931 G/A cg25358565 chr5:93447407 FAM172A 0.95 7.97 0.58 8.71e-13 Diabetic retinopathy; TGCT cis rs3617 0.572 rs2245538 chr3:52852060 T/C cg10802521 chr3:52805072 NEK4 -0.6 -6.89 -0.53 2.46e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs11650494 0.831 rs7216993 chr17:47454263 A/G cg08112188 chr17:47440006 ZNF652 0.92 5.02 0.41 1.74e-6 Prostate cancer; TGCT cis rs514406 0.825 rs9661082 chr1:53245472 A/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs12971120 1.000 rs734559 chr18:72179579 G/A cg26446133 chr18:72167187 CNDP2 -0.33 -6.03 -0.48 1.74e-8 Refractive error; TGCT cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg04025307 chr7:1156635 C7orf50 0.2 4.73 0.39 5.94e-6 Longevity;Endometriosis; TGCT cis rs8013055 0.706 rs8003957 chr14:105971702 A/G cg19700328 chr14:106028568 NA -0.57 -6.12 -0.48 1.12e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7618915 0.547 rs34537256 chr3:52657472 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.07 0.48 1.47e-8 Bipolar disorder; TGCT cis rs4372836 1.000 rs4666119 chr2:28975690 C/G cg09522027 chr2:28974177 PPP1CB -0.62 -5.43 -0.44 2.87e-7 Body mass index; TGCT cis rs12188164 1.000 rs34847072 chr5:437862 G/C cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.74 -0.39 5.75e-6 Cystic fibrosis severity; TGCT cis rs2742417 0.603 rs2742449 chr3:45764544 T/C cg04837898 chr3:45731254 SACM1L -0.65 -6.95 -0.53 1.84e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs344364 0.511 rs2917515 chr16:1945271 G/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT trans rs61931739 0.500 rs7306435 chr12:34482933 A/G cg26384229 chr12:38710491 ALG10B -0.79 -7.45 -0.56 1.36e-11 Morning vs. evening chronotype; TGCT cis rs28386778 0.897 rs4968599 chr17:61835992 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs12477438 0.798 rs1453561 chr2:99613924 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.75 -0.46 6.58e-8 Chronic sinus infection; TGCT cis rs875971 0.964 rs11765965 chr7:65842221 A/G cg11764359 chr7:65958608 NA 0.61 5.47 0.44 2.35e-7 Aortic root size; TGCT cis rs7572733 0.555 rs7420608 chr2:198915930 A/T cg00792783 chr2:198669748 PLCL1 0.57 4.97 0.41 2.14e-6 Dermatomyositis; TGCT cis rs2760061 0.819 rs964941 chr1:228193857 G/A cg18477163 chr1:228402036 OBSCN 0.34 7.16 0.54 6.26e-11 Diastolic blood pressure; TGCT cis rs7914558 1.000 rs12255047 chr10:104760752 G/A cg05855489 chr10:104503620 C10orf26 0.51 4.53 0.38 1.39e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.0 8.22 0.59 2.32e-13 Platelet count; TGCT cis rs7918232 0.941 rs10741128 chr10:27411509 G/A cg14442939 chr10:27389572 ANKRD26 0.72 5.35 0.43 4.16e-7 Breast cancer; TGCT cis rs114540395 0.925 rs115878498 chr10:103447267 G/A cg03300883 chr10:102748874 C10orf2 0.44 4.89 0.4 3.06e-6 Schizophrenia; TGCT cis rs6582630 0.599 rs8175936 chr12:38426315 C/G cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs73058052 0.597 rs11083979 chr19:50096144 T/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.65 5.22 0.42 7.33e-7 Fibrinogen levels; TGCT cis rs826838 0.935 rs1684406 chr12:39127265 A/G cg26384229 chr12:38710491 ALG10B -0.86 -7.72 -0.57 3.37e-12 Heart rate; TGCT cis rs1371867 0.641 rs1788209 chr8:101337056 C/T cg00191853 chr8:101177733 SPAG1 -0.23 -4.73 -0.39 6.08e-6 Atrioventricular conduction; TGCT cis rs514475 0.526 rs12201110 chr6:137954963 G/A cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs244731 0.959 rs6872021 chr5:176610012 G/A cg16006841 chr5:176797999 RGS14 -0.53 -6.95 -0.53 1.88e-10 Urate levels in lean individuals; TGCT cis rs892961 0.932 rs12452788 chr17:75406866 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.75 0.52 5.04e-10 Airflow obstruction; TGCT cis rs7192750 0.586 rs8058118 chr16:71959733 T/C cg06353428 chr16:71660113 MARVELD3 0.81 7.15 0.54 6.72e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs514406 0.584 rs12095247 chr1:53193796 A/C cg24675658 chr1:53192096 ZYG11B 0.86 10.84 0.7 1.11e-19 Monocyte count; TGCT cis rs2766547 0.669 rs1831030 chr6:35706933 C/T cg01618151 chr6:35707957 C6orf81 -0.27 -4.6 -0.38 1.04e-5 Eosinophil percentage of granulocytes; TGCT cis rs910316 0.726 rs175040 chr14:75469555 A/G cg11812906 chr14:75593930 NEK9 -0.58 -5.55 -0.45 1.67e-7 Height; TGCT cis rs10504229 1.000 rs67096506 chr8:58195655 G/A cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs597539 0.690 rs552517 chr11:68625286 T/G cg21963583 chr11:68658836 MRPL21 0.39 6.34 0.49 3.91e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7681440 0.967 rs1372517 chr4:90755909 G/A cg14346243 chr4:90757452 SNCA -0.58 -5.74 -0.46 6.79e-8 Dementia with Lewy bodies; TGCT cis rs7103648 0.966 rs1377416 chr11:47416746 C/T cg20307385 chr11:47447363 PSMC3 1.01 11.91 0.73 2.85e-22 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs12220238 1.000 rs10824151 chr10:76092179 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.95 6.66 0.51 8.08e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs11190604 1.000 rs7071271 chr10:102264824 G/A cg23241863 chr10:102295624 HIF1AN 0.67 5.13 0.42 1.1e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2439831 1.000 rs471229 chr15:43733994 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs2836974 0.931 rs2989330 chr21:40716209 A/G cg11644478 chr21:40555479 PSMG1 0.87 7.35 0.55 2.36e-11 Cognitive function; TGCT cis rs9921338 0.781 rs7205925 chr16:11462478 C/T cg00044050 chr16:11439710 C16orf75 -0.63 -4.68 -0.39 7.33e-6 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs6598955 0.543 rs6699798 chr1:26556442 G/T cg04990556 chr1:26633338 UBXN11 0.8 7.3 0.55 3.01e-11 Obesity-related traits; TGCT cis rs6121246 0.909 rs7272062 chr20:30259145 A/G cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs290268 1.000 rs188313 chr9:93548302 C/T cg02608019 chr9:93564028 SYK 0.48 4.8 0.4 4.42e-6 Platelet count; TGCT cis rs11098499 0.863 rs6534139 chr4:120449456 A/G cg09307838 chr4:120376055 NA -0.71 -6.47 -0.5 2.03e-9 Corneal astigmatism; TGCT cis rs17125944 0.686 rs55685925 chr14:53334546 A/G cg00686598 chr14:53173677 PSMC6 -0.87 -4.5 -0.37 1.53e-5 Alzheimer's disease (late onset); TGCT cis rs11148252 0.774 rs7993748 chr13:52941631 C/T cg00495681 chr13:53174319 NA 0.55 5.42 0.44 3e-7 Lewy body disease; TGCT cis rs7582180 0.629 rs6757754 chr2:100951273 C/T cg08017756 chr2:100939284 LONRF2 0.3 4.95 0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.846 rs1660323 chr8:101278724 T/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.5 -0.37 1.53e-5 Atrioventricular conduction; TGCT cis rs28386778 0.799 rs2665802 chr17:61995030 A/T cg06896619 chr17:61851486 DDX42;CCDC47 0.53 5.56 0.45 1.58e-7 Prudent dietary pattern; TGCT cis rs1055129 0.560 rs56248937 chr17:73915153 T/A cg10935138 chr17:73851978 WBP2 0.54 4.71 0.39 6.58e-6 White matter hyperintensity burden; TGCT cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs3540 0.574 rs2601205 chr15:90961813 A/G cg22089800 chr15:90895588 ZNF774 0.76 8.15 0.59 3.42e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7959452 0.590 rs56054057 chr12:69775972 C/T cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs6570726 1.000 rs374464 chr6:145846679 A/C cg23711669 chr6:146136114 FBXO30 0.68 6.26 0.49 5.81e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs13393800 0.536 rs2697802 chr2:233381175 C/T cg26635044 chr2:233757626 NGEF 0.17 4.89 0.4 3.11e-6 Height; TGCT cis rs909674 0.731 rs6001594 chr22:39837472 C/T cg11247378 chr22:39784982 NA -0.73 -8.47 -0.61 5.86e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7611238 0.560 rs6771771 chr3:195083233 T/A cg27323046 chr3:195102265 ACAP2 0.39 5.1 0.42 1.25e-6 Body mass index; TGCT cis rs10791323 0.572 rs4412766 chr11:133742811 A/C cg15485101 chr11:133734466 NA 0.41 5.83 0.46 4.6e-8 Childhood ear infection; TGCT cis rs9436747 0.777 rs1475398 chr1:65983257 C/G cg14976592 chr1:65886160 LEPROT;LEPR 0.58 5.05 0.41 1.51e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7095607 0.813 rs4451608 chr10:69933238 C/A cg18986048 chr10:69913749 MYPN 0.46 5.24 0.43 6.65e-7 Lung function (FVC); TGCT cis rs910316 0.664 rs2098252 chr14:75492732 T/C cg08847533 chr14:75593920 NEK9 0.84 8.77 0.62 1.16e-14 Height; TGCT cis rs9527 0.571 rs3740400 chr10:104629465 T/G cg04362960 chr10:104952993 NT5C2 0.56 4.83 0.4 4e-6 Arsenic metabolism; TGCT cis rs66569888 0.507 rs11673736 chr2:106886935 T/C cg15412446 chr2:106886593 NA -0.53 -6.8 -0.52 3.87e-10 Facial morphology (factor 23); TGCT cis rs12497850 0.931 rs4974080 chr3:49030828 A/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.51 0.44 1.95e-7 Parkinson's disease; TGCT cis rs62380364 0.602 rs665324 chr5:88055517 T/C cg24804195 chr5:87968844 LOC645323 -0.57 -5.56 -0.45 1.59e-7 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.502 rs4559747 chr12:38436235 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.58 0.56 6.92e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs79057730 0.599 rs112891948 chr7:816059 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.65 6.07 0.48 1.42e-8 Initial pursuit acceleration; TGCT cis rs4820539 1.000 rs5759595 chr22:23471624 G/A cg21100191 chr22:23484243 RTDR1 0.89 10.61 0.69 4.23e-19 Bone mineral density; TGCT cis rs6993813 0.620 rs12056346 chr8:120042191 T/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs12142240 0.698 rs55971480 chr1:46823206 G/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs992157 0.764 rs1870123 chr2:219187698 G/A cg00012203 chr2:219082015 ARPC2 0.71 6.65 0.51 8.23e-10 Colorectal cancer; TGCT cis rs7267979 0.966 rs2261698 chr20:25259910 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs3792900 0.509 rs6596299 chr5:135570567 A/C cg00308130 chr5:135415190 NA 0.32 4.72 0.39 6.26e-6 Insomnia;Blood protein levels; TGCT cis rs7617480 0.519 rs6790914 chr3:49206318 G/C cg05785598 chr3:49045655 WDR6 0.39 5.17 0.42 9.24e-7 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs62244186 0.715 rs11130032 chr3:44704083 G/A cg02073558 chr3:44770973 ZNF501 0.63 6.03 0.48 1.77e-8 Depressive symptoms; TGCT cis rs11264213 0.591 rs619666 chr1:36488956 C/T cg27506609 chr1:36549197 TEKT2 -0.31 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT cis rs1371867 0.817 rs7846076 chr8:101327629 A/G cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs208520 0.742 rs208454 chr6:66907783 T/C cg07460842 chr6:66804631 NA -0.9 -9.14 -0.63 1.54e-15 Exhaled nitric oxide output; TGCT cis rs244731 0.959 rs4976677 chr5:176629546 G/A cg06060754 chr5:176797920 RGS14 -0.44 -6.2 -0.49 7.79e-9 Urate levels in lean individuals; TGCT cis rs3096299 0.967 rs7205785 chr16:89458984 A/G cg02187348 chr16:89574699 SPG7 0.5 4.7 0.39 6.85e-6 Multiple myeloma (IgH translocation); TGCT cis rs5750830 0.594 rs6001568 chr22:39775786 G/A cg02038168 chr22:39784481 NA -0.63 -5.38 -0.44 3.5e-7 Intelligence (multi-trait analysis); TGCT cis rs28595532 1.000 rs116030177 chr4:119650768 T/C cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT trans rs797680 0.789 rs35940311 chr1:93663604 G/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.95 -0.53 1.87e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs17433780 0.504 rs1409150 chr1:89473175 A/G cg09516651 chr1:89888402 LOC400759 0.24 5.03 0.41 1.69e-6 Carotid intima media thickness; TGCT cis rs10782582 0.593 rs12132750 chr1:76136222 A/G cg10523679 chr1:76189770 ACADM -0.68 -7.05 -0.53 1.11e-10 Daytime sleep phenotypes; TGCT cis rs17253792 0.822 rs17747083 chr14:56110594 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs10927875 0.541 rs1048334 chr1:16340761 T/C cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT cis rs4927850 0.529 rs6800500 chr3:195833507 T/C cg02975922 chr3:195473998 MUC4 -0.24 -4.68 -0.39 7.34e-6 Pancreatic cancer; TGCT cis rs11785400 1.000 rs7002932 chr8:143738816 C/A cg24634471 chr8:143751801 JRK 0.57 6.12 0.48 1.11e-8 Schizophrenia; TGCT cis rs4711350 0.953 rs1951930 chr6:33782655 C/A cg18005901 chr6:33739558 LEMD2 -0.57 -5.8 -0.46 5.11e-8 Schizophrenia; TGCT cis rs7044106 0.708 rs920745 chr9:123429943 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.47 0.5 2.01e-9 Hip circumference adjusted for BMI; TGCT cis rs10791097 0.694 rs7106973 chr11:130758113 G/A cg05962950 chr11:130786565 SNX19 0.94 12.01 0.73 1.58e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7647973 1.000 rs12583 chr3:49571462 G/T cg07636037 chr3:49044803 WDR6 -0.59 -4.6 -0.38 1.03e-5 Menarche (age at onset); TGCT cis rs9467711 0.591 rs28360595 chr6:26030044 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.59 -4.63 -0.38 9.26e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs739496 0.843 rs7398705 chr12:112016016 A/C cg10833066 chr12:111807467 FAM109A -0.37 -5.41 -0.44 3.17e-7 Platelet count; TGCT cis rs6138458 0.743 rs3746330 chr20:24999795 A/G cg26195577 chr20:24973756 C20orf3 1.02 9.35 0.64 4.61e-16 Blood protein levels; TGCT cis rs2721173 0.619 rs997258 chr8:145903077 C/A cg15320075 chr8:145703422 NA -0.64 -5.84 -0.46 4.31e-8 Educational attainment;Cognitive ability (multi-trait analysis);Intelligence (multi-trait analysis); TGCT cis rs7811142 0.945 rs6955362 chr7:100056166 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs6582630 0.576 rs4882372 chr12:38356609 C/A cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg13866156 chr1:1669148 SLC35E2 -0.21 -5.12 -0.42 1.11e-6 Body mass index; TGCT cis rs4901869 0.966 rs4901870 chr14:59334221 A/T cg02291164 chr14:59296302 NA -0.25 -4.65 -0.39 8.39e-6 Panic disorder; TGCT cis rs2963155 0.518 rs864355 chr5:142633229 A/G cg17617527 chr5:142782415 NR3C1 0.85 6.29 0.49 4.9e-9 Breast cancer; TGCT cis rs3733585 0.660 rs13122290 chr4:9933832 A/G cg00071950 chr4:10020882 SLC2A9 -0.61 -7.25 -0.55 3.96e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9653442 0.835 rs11694875 chr2:100732845 A/G cg22139774 chr2:100720529 AFF3 0.45 7.92 0.58 1.17e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7635838 0.827 rs9826044 chr3:11458075 A/G cg00170343 chr3:11313890 ATG7 0.64 6.16 0.48 9.46e-9 HDL cholesterol; TGCT cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg08645402 chr16:4508243 NA 0.21 5.36 0.43 3.98e-7 Schizophrenia; TGCT cis rs236907 0.859 rs17596081 chr1:171746276 G/T cg20598894 chr1:171756153 METTL13 -0.18 -4.53 -0.38 1.34e-5 Mean platelet volume; TGCT cis rs8141529 0.732 rs5762815 chr22:29205076 A/G cg02153584 chr22:29168773 CCDC117 0.67 5.68 0.45 9.04e-8 Lymphocyte counts; TGCT cis rs7647973 0.626 rs62262672 chr3:49655927 T/A cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.59 -0.38 1.08e-5 Menarche (age at onset); TGCT cis rs6547741 0.967 rs4665986 chr2:27755168 G/A cg27432699 chr2:27873401 GPN1 0.18 4.62 0.38 9.37e-6 Oral cavity cancer; TGCT cis rs12541335 0.639 rs6993855 chr8:22163797 A/G cg26039829 chr8:22132926 PIWIL2 0.25 4.67 0.39 7.62e-6 Hypertriglyceridemia; TGCT cis rs13064411 0.696 rs2129434 chr3:113138763 A/C cg18753928 chr3:113234510 CCDC52 -0.71 -5.62 -0.45 1.23e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7772486 0.806 rs2265477 chr6:146212338 T/C cg05347473 chr6:146136440 FBXO30 0.53 5.23 0.43 6.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2458413 0.500 rs2514666 chr8:105351943 C/T cg04554929 chr8:105342491 NA 0.5 6.07 0.48 1.42e-8 Paget's disease; TGCT cis rs9443645 0.901 rs2152951 chr6:79762172 A/G cg09184832 chr6:79620586 NA 0.44 4.9 0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT cis rs10114408 0.918 rs4475560 chr9:96662067 T/C cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs514406 0.536 rs878957 chr1:53197559 C/T cg25767906 chr1:53392781 SCP2 0.49 5.37 0.43 3.73e-7 Monocyte count; TGCT cis rs9611565 0.879 rs5758311 chr22:41759375 G/T cg17554472 chr22:41940697 POLR3H -0.45 -4.91 -0.4 2.84e-6 Vitiligo; TGCT cis rs2296887 0.841 rs945781 chr10:104085921 A/G cg26089160 chr10:104170217 PSD 0.6 5.53 0.44 1.79e-7 Parkinson's disease; TGCT cis rs587847 0.708 rs12902322 chr15:37623366 A/G cg00216138 chr15:37171175 LOC145845 0.3 4.52 0.38 1.43e-5 Intraocular pressure; TGCT cis rs7618915 0.501 rs2336149 chr3:52692124 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs57221529 0.766 rs4245972 chr5:578572 A/G cg20362242 chr5:692897 TPPP 0.48 4.51 0.38 1.47e-5 Lung disease severity in cystic fibrosis; TGCT cis rs4803468 0.967 rs7259900 chr19:41889429 A/T cg09537434 chr19:41945824 ATP5SL -0.89 -9.96 -0.67 1.6e-17 Height; TGCT cis rs8032315 0.965 rs35346340 chr15:91427872 G/C cg03209642 chr15:91427605 FES 0.52 4.91 0.4 2.81e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1150668 0.796 rs2247002 chr6:28397951 G/C cg13525197 chr6:28411240 ZSCAN23 -0.53 -5.14 -0.42 1.03e-6 Pubertal anthropometrics; TGCT cis rs9894429 0.789 rs8074989 chr17:79598728 G/C cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs112591243 0.685 rs2839362 chr21:48024626 G/A cg10657630 chr21:48055338 PRMT2 1.05 6.12 0.48 1.12e-8 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs478304 0.514 rs75601653 chr11:65483370 C/G cg12758867 chr11:65354231 EHBP1L1 0.26 4.48 0.37 1.67e-5 Acne (severe); TGCT cis rs9682041 0.932 rs6782252 chr3:170133639 C/T cg11886554 chr3:170076028 SKIL 0.87 6.38 0.5 3.18e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs9916302 0.904 rs12952384 chr17:37669536 T/C cg15445000 chr17:37608096 MED1 0.32 4.66 0.39 8.18e-6 Glomerular filtration rate (creatinine); TGCT cis rs60843830 1.000 rs3791221 chr2:226933 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.75 7.55 0.56 8.02e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg00989853 chr1:209979345 IRF6 0.41 4.66 0.39 8.16e-6 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg06634786 chr22:41940651 POLR3H -0.72 -6.68 -0.51 7.15e-10 Vitiligo; TGCT cis rs1865760 0.566 rs7772312 chr6:26049616 G/C cg17042849 chr6:26104293 HIST1H4C -0.62 -5.41 -0.44 3.18e-7 Height; TGCT cis rs6570726 0.791 rs383841 chr6:145888329 G/T cg23711669 chr6:146136114 FBXO30 -0.89 -9.93 -0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg07636037 chr3:49044803 WDR6 -0.85 -8.88 -0.62 6.21e-15 Menarche (age at onset); TGCT cis rs6424115 0.767 rs11591202 chr1:24102080 A/C cg15997130 chr1:24165203 NA -0.69 -6.7 -0.52 6.61e-10 Immature fraction of reticulocytes; TGCT cis rs7208859 0.623 rs216423 chr17:28942109 G/C cg19761014 chr17:28927070 LRRC37B2 0.55 4.77 0.39 5.12e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2243480 0.901 rs3813708 chr7:65305632 C/A cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT cis rs453301 0.624 rs2979256 chr8:8871710 C/T cg15556689 chr8:8085844 FLJ10661 0.76 6.59 0.51 1.13e-9 Joint mobility (Beighton score); TGCT cis rs12908161 0.959 rs12906348 chr15:85329421 A/C cg11189052 chr15:85197271 WDR73 0.71 5.92 0.47 2.93e-8 Schizophrenia; TGCT cis rs9611565 0.546 rs5758431 chr22:42109917 A/G cg06634786 chr22:41940651 POLR3H 0.89 9.09 0.63 1.96e-15 Vitiligo; TGCT cis rs1723838 1.000 rs2886812 chr11:73605159 T/G cg18195628 chr11:73498948 MRPL48 0.92 4.5 0.38 1.51e-5 Obesity-related traits; TGCT cis rs2980439 0.517 rs712253 chr8:8103782 C/T cg08975724 chr8:8085496 FLJ10661 -0.54 -4.84 -0.4 3.84e-6 Neuroticism; TGCT cis rs3892630 0.588 rs1976501 chr19:33208155 C/T cg22980127 chr19:33182716 NUDT19 0.77 6.36 0.5 3.47e-9 Red blood cell traits; TGCT cis rs6951245 0.554 rs10270249 chr7:1151886 G/T cg09177884 chr7:1199841 ZFAND2A -0.69 -5.47 -0.44 2.41e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2795502 1.000 rs3121323 chr10:43377166 A/G cg20628663 chr10:43360327 NA -0.46 -6.63 -0.51 9.28e-10 Blood protein levels; TGCT cis rs7089973 0.604 rs765174 chr10:116601888 C/T cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs4786125 0.665 rs1565633 chr16:6919428 G/C cg03623568 chr16:6915990 A2BP1 -0.45 -6.77 -0.52 4.65e-10 Heart rate variability traits (SDNN); TGCT cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.27 0.49 5.58e-9 Mean platelet volume; TGCT cis rs9952991 0.566 rs514000 chr18:12854072 C/T cg23598886 chr18:12777645 NA 0.55 4.77 0.39 5.06e-6 Inflammatory skin disease; TGCT cis rs11098499 0.754 rs9999724 chr4:120239944 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9921192 0.967 rs3747571 chr16:4323983 A/G cg00021532 chr16:4324280 TFAP4 0.83 9.57 0.65 1.39e-16 Prostate-specific antigen levels; TGCT cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg07061783 chr6:25882402 NA -0.42 -4.51 -0.38 1.51e-5 Blood metabolite levels; TGCT cis rs12477438 0.520 rs6542869 chr2:99783403 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs228437 0.657 rs9402619 chr6:134910055 A/C cg09872934 chr6:134495829 SGK1 0.61 4.83 0.4 3.89e-6 Melanoma; TGCT cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7191439 0.858 rs11076701 chr16:88774525 A/G cg27087555 chr16:88793112 FAM38A -0.51 -6.05 -0.48 1.55e-8 Plateletcrit; TGCT cis rs514406 0.861 rs4926577 chr1:53226788 C/A cg25767906 chr1:53392781 SCP2 0.48 5.56 0.45 1.57e-7 Monocyte count; TGCT cis rs2839186 0.588 rs7280110 chr21:47619039 G/A cg13012494 chr21:47604986 C21orf56 -0.39 -4.66 -0.39 7.88e-6 Testicular germ cell tumor; TGCT cis rs6500602 0.627 rs2270363 chr16:4526292 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 4.87 0.4 3.31e-6 Schizophrenia; TGCT cis rs7937682 0.855 rs7109592 chr11:111533105 C/A cg09085632 chr11:111637200 PPP2R1B -1.14 -11.73 -0.73 7.67e-22 Primary sclerosing cholangitis; TGCT cis rs2354432 0.599 rs4950423 chr1:146854539 T/C cg25205988 chr1:146714368 CHD1L 1.32 5.88 0.47 3.62e-8 Mitochondrial DNA levels; TGCT trans rs208515 0.525 rs10455593 chr6:66691341 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs4886920 0.563 rs12915515 chr15:78075555 A/T cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.37e-6 Neuroticism; TGCT cis rs734999 0.545 rs12730932 chr1:2559589 T/G cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs55883249 1.000 rs62119422 chr2:9726599 A/G cg23886495 chr2:9695866 ADAM17 0.77 4.69 0.39 7.19e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs6754311 0.834 rs12465802 chr2:136381348 A/G cg07169764 chr2:136633963 MCM6 -0.53 -4.69 -0.39 7.11e-6 Mosquito bite size; TGCT cis rs2742234 0.955 rs2503849 chr10:43672776 G/A cg02780029 chr10:43622663 RET -0.26 -4.94 -0.41 2.49e-6 Hirschsprung disease; TGCT cis rs6088580 0.634 rs4911419 chr20:32995873 G/A cg24642439 chr20:33292090 TP53INP2 -0.49 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs6840360 0.615 rs12503677 chr4:152610543 A/G cg17479576 chr4:152424074 FAM160A1 -0.54 -5.28 -0.43 5.69e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg06634786 chr22:41940651 POLR3H -0.72 -6.68 -0.51 7.15e-10 Vitiligo; TGCT cis rs17270561 1.000 rs17270561 chr6:25820439 A/C cg17691542 chr6:26056736 HIST1H1C -0.76 -4.88 -0.4 3.2e-6 Iron status biomarkers; TGCT cis rs698813 0.572 rs12712914 chr2:44478649 C/G cg00619915 chr2:44497795 NA -0.24 -5.61 -0.45 1.26e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs2692947 0.599 rs7561198 chr2:96774981 C/G cg23100626 chr2:96804247 ASTL -0.42 -5.0 -0.41 1.92e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7660520 0.524 rs4862100 chr4:183732709 G/T cg04181038 chr4:183730758 NA 0.65 6.11 0.48 1.2e-8 Pediatric autoimmune diseases; TGCT cis rs896854 0.812 rs12546365 chr8:95911477 T/C cg23172400 chr8:95962367 TP53INP1 -0.34 -5.55 -0.45 1.65e-7 Type 2 diabetes; TGCT cis rs7584330 0.554 rs56853932 chr2:238428327 T/C cg08992911 chr2:238395768 MLPH 0.67 4.52 0.38 1.41e-5 Prostate cancer; TGCT cis rs34734847 0.933 rs7975067 chr12:121099454 G/A cg21892295 chr12:121157589 UNC119B -0.19 -4.51 -0.38 1.47e-5 Mean corpuscular volume; TGCT cis rs9486719 1.000 rs2142653 chr6:96871520 C/A cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT trans rs877282 0.629 rs78997110 chr10:764388 A/G cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT trans rs208520 0.754 rs851593 chr6:66875783 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.96 10.31 0.68 2.29e-18 Exhaled nitric oxide output; TGCT cis rs4919669 0.668 rs11191343 chr10:104345225 G/A cg05855489 chr10:104503620 C10orf26 0.73 4.71 0.39 6.65e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs909674 0.818 rs8136980 chr22:39844574 G/A cg01416388 chr22:39784598 NA -0.69 -6.62 -0.51 9.49e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7940866 0.903 rs2324316 chr11:130872353 G/T cg05962950 chr11:130786565 SNX19 0.69 6.64 0.51 8.78e-10 Schizophrenia; TGCT cis rs17387100 0.551 rs2677783 chr4:16020318 G/A cg13480465 chr4:16795757 LDB2 -0.42 -5.33 -0.43 4.56e-7 Suicide attempts in depression or bipolar disorder; TGCT cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9443645 0.901 rs9361466 chr6:79618352 T/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs4595586 0.525 rs7970652 chr12:39374873 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs4664308 1.000 rs6707458 chr2:160914540 G/T cg03641300 chr2:160917029 PLA2R1 -0.26 -6.42 -0.5 2.61e-9 Idiopathic membranous nephropathy; TGCT cis rs6582630 0.615 rs3914894 chr12:38480280 C/T cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4523957 0.651 rs9910413 chr17:2081419 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6519955 0.796 rs4072455 chr22:46422938 T/C cg05468064 chr22:46423449 NA 0.58 6.07 0.48 1.47e-8 Dupuytren's disease; TGCT cis rs4319547 0.656 rs10734918 chr12:122921512 A/C cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.38 -0.44 3.58e-7 Body mass index; TGCT cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg02487422 chr3:49467188 NICN1 0.49 4.53 0.38 1.38e-5 Menarche (age at onset); TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs6429082 0.755 rs291384 chr1:235644300 C/T cg26050004 chr1:235667680 B3GALNT2 0.59 5.26 0.43 6.02e-7 Adiposity; TGCT cis rs3540 0.920 rs7182658 chr15:91019248 A/T cg22089800 chr15:90895588 ZNF774 0.72 6.46 0.5 2.16e-9 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg17554472 chr22:41940697 POLR3H -0.5 -5.37 -0.43 3.72e-7 Vitiligo; TGCT cis rs7929679 0.875 rs1891291 chr11:34813620 T/C cg18414381 chr11:34642885 EHF -0.24 -4.8 -0.4 4.52e-6 Chronic obstructive pulmonary disease-related biomarkers;Lung disease severity in cystic fibrosis; TGCT cis rs7412746 0.611 rs2864873 chr1:150814174 A/G cg09365446 chr1:150670422 GOLPH3L 0.37 5.34 0.43 4.18e-7 Melanoma; TGCT cis rs11578119 0.902 rs1591150 chr1:170426839 A/G cg09767346 chr1:170501363 GORAB -0.72 -5.7 -0.46 8.13e-8 Male-pattern baldness; TGCT cis rs2762353 0.574 rs4419666 chr6:25693274 C/T cg03264133 chr6:25882463 NA 0.87 8.61 0.61 2.72e-14 Blood metabolite levels; TGCT cis rs60871478 0.898 rs4725241 chr7:796883 C/T cg05535760 chr7:792225 HEATR2 0.32 4.51 0.38 1.49e-5 Cerebrospinal P-tau181p levels; TGCT cis rs2013441 1.000 rs2703801 chr17:20100600 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs7586879 0.575 rs6744205 chr2:25133148 T/C cg01884057 chr2:25150051 NA 0.36 7.1 0.54 8.63e-11 Body mass index; TGCT cis rs3924048 0.559 rs4580 chr1:12628188 T/C cg00291366 chr1:12616550 NA 0.31 4.89 0.4 3.08e-6 Optic cup area; TGCT cis rs4727027 0.870 rs1568945 chr7:148874112 T/G cg23583168 chr7:148888333 NA -0.74 -9.81 -0.66 3.64e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4319547 0.695 rs10773152 chr12:122910180 T/C cg08088222 chr12:122070432 ORAI1 0.26 4.53 0.38 1.34e-5 Body mass index; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg23131131 chr22:24373011 LOC391322 -0.81 -8.72 -0.62 1.53e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9486719 1.000 rs2499804 chr6:96861216 A/G cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7666738 0.830 rs7662596 chr4:99019962 G/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 1.000 rs4919469 chr10:102298855 C/A cg16342193 chr10:102329863 NA -0.41 -5.11 -0.42 1.18e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9341808 0.644 rs62408577 chr6:80942024 T/A cg08355045 chr6:80787529 NA -0.28 -4.52 -0.38 1.45e-5 Sitting height ratio; TGCT cis rs1775715 0.737 rs2778661 chr10:32159191 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6061231 0.755 rs11699160 chr20:60958651 T/C cg15674680 chr20:60982522 CABLES2 0.5 4.47 0.37 1.74e-5 Colorectal cancer; TGCT cis rs9733 0.596 rs1136808 chr1:150702717 G/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs875971 0.660 rs10215132 chr7:66054406 C/A cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.45e-7 Aortic root size; TGCT cis rs11208691 0.513 rs60466849 chr1:66107714 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.58 4.53 0.38 1.35e-5 Lymphocyte percentage of white cells; TGCT cis rs9611565 0.625 rs2076199 chr22:41903743 G/T cg17554472 chr22:41940697 POLR3H -0.44 -4.77 -0.39 5.17e-6 Vitiligo; TGCT trans rs629535 0.514 rs55653755 chr8:70154383 A/C cg21567404 chr3:27674614 NA -0.51 -7.55 -0.56 8.15e-12 Dupuytren's disease; TGCT cis rs4074961 0.669 rs4652964 chr1:38078300 A/G cg11397548 chr1:38022522 DNALI1 0.43 4.78 0.39 4.95e-6 Axial length; TGCT cis rs9650657 0.615 rs6601536 chr8:10696311 C/G cg16664915 chr8:10907788 XKR6 -0.29 -4.6 -0.38 1.05e-5 Neuroticism; TGCT cis rs853679 0.567 rs16894106 chr6:28400339 G/A cg18815343 chr6:28367644 ZSCAN12 -0.5 -4.56 -0.38 1.19e-5 Depression; TGCT cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs12145833 0.538 rs61833885 chr1:243397188 C/A cg02356786 chr1:243265016 LOC731275 0.6 5.18 0.42 8.64e-7 Obesity (early onset extreme); TGCT cis rs7635838 0.859 rs9869977 chr3:11480081 C/A cg00170343 chr3:11313890 ATG7 0.64 6.06 0.48 1.5e-8 HDL cholesterol; TGCT cis rs17741873 0.836 rs10824039 chr10:75602849 G/A cg07699608 chr10:75541558 CHCHD1 0.7 4.75 0.39 5.43e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs9811920 0.609 rs7636447 chr3:99612677 G/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.6 -6.82 -0.52 3.63e-10 Axial length; TGCT cis rs796364 0.616 rs6718118 chr2:200691852 G/T cg17644776 chr2:200775616 C2orf69 -0.34 -4.84 -0.4 3.76e-6 Schizophrenia; TGCT cis rs7666738 0.791 rs2865953 chr4:99040319 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7809950 1.000 rs67982599 chr7:107100104 T/G cg23024343 chr7:107201750 COG5 -0.34 -5.43 -0.44 2.92e-7 Coronary artery disease; TGCT cis rs12142240 0.698 rs58162700 chr1:46816659 T/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs1865760 0.516 rs9393683 chr6:26066198 A/G cg17042849 chr6:26104293 HIST1H4C -0.66 -5.85 -0.47 4.02e-8 Height; TGCT cis rs12477438 0.520 rs6739579 chr2:99731552 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs12477438 0.520 rs11677247 chr2:99756358 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs7666738 0.791 rs28579101 chr4:98843203 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.17 0.48 8.71e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 1.000 rs9291659 chr4:17662360 A/C cg18681998 chr4:17616180 MED28 0.94 11.11 0.71 2.57e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4389656 0.883 rs34338480 chr5:6712854 T/C cg10857441 chr5:6722123 POLS 0.22 4.47 0.37 1.73e-5 Coronary artery disease; TGCT trans rs797680 0.786 rs7532195 chr1:93617403 T/G cg27528825 chr2:159282178 CCDC148 -0.35 -6.78 -0.52 4.27e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs11764590 0.671 rs62444906 chr7:2083161 G/T cg25206134 chr2:45395956 NA 0.97 6.73 0.52 5.68e-10 Neuroticism; TGCT cis rs9296661 0.868 rs2225051 chr6:51668394 C/T cg00593404 chr6:52377740 TRAM2 -0.27 -4.49 -0.37 1.62e-5 Weight loss (gastric bypass surgery); TGCT cis rs9611565 0.918 rs9611562 chr22:41760172 T/G cg17554472 chr22:41940697 POLR3H -0.5 -5.2 -0.42 8.14e-7 Vitiligo; TGCT cis rs7829975 0.501 rs74345345 chr8:8578435 C/G cg17143192 chr8:8559678 CLDN23 -0.52 -5.25 -0.43 6.29e-7 Mood instability; TGCT cis rs35306767 0.903 rs17159950 chr10:875287 T/G cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs644799 1.000 rs546809 chr11:95579938 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 9.9 0.66 2.27e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3806843 0.735 rs809635 chr5:140081791 A/G cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs11190604 0.767 rs4919458 chr10:102177728 G/A cg16342193 chr10:102329863 NA 0.37 4.79 0.39 4.73e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg08859206 chr1:53392774 SCP2 -0.42 -6.4 -0.5 2.95e-9 Monocyte count; TGCT cis rs950169 0.840 rs4842853 chr15:84942304 G/T cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs7552404 1.000 rs4949879 chr1:76237143 G/A cg22875332 chr1:76189707 ACADM 0.76 8.83 0.62 8.53e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4073582 0.595 rs555360 chr11:65960061 T/C cg16950941 chr11:66035639 RAB1B -0.55 -5.21 -0.42 7.79e-7 Gout; TGCT cis rs7666738 0.830 rs13328005 chr4:99055480 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.87e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs904251 0.504 rs2797795 chr6:37480683 T/C cg01843034 chr6:37503916 NA -0.56 -7.56 -0.56 7.84e-12 Cognitive performance; TGCT cis rs11031096 0.542 rs1452048 chr11:3965428 G/T cg18678763 chr11:4115507 RRM1 -0.42 -5.14 -0.42 1.05e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1552244 0.882 rs67895180 chr3:10026079 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs17345786 0.861 rs17402964 chr3:101067945 C/T cg12386194 chr3:101231763 SENP7 0.66 6.45 0.5 2.29e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs245880 0.765 rs245893 chr7:29191507 G/C cg17163760 chr7:29186267 CPVL -0.39 -4.89 -0.4 3.12e-6 Warfarin maintenance dose; TGCT cis rs295140 0.605 rs296818 chr2:201176944 C/T cg23649088 chr2:200775458 C2orf69 0.27 4.43 0.37 2.01e-5 QT interval; TGCT cis rs4919694 1.000 rs12241091 chr10:104808997 G/A cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT trans rs1005277 0.602 rs1740743 chr10:38519222 C/T cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs2594989 0.943 rs2443713 chr3:11537540 T/G cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.6e-5 Circulating chemerin levels; TGCT cis rs72615157 0.634 rs74774557 chr7:99810425 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.61 -4.74 -0.39 5.85e-6 Lung function (FEV1/FVC); TGCT cis rs4925386 1.000 rs4925389 chr20:60922512 G/A cg06026331 chr20:60912101 LAMA5 -0.28 -5.11 -0.42 1.16e-6 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs2153535 0.601 rs9502715 chr6:8455709 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs6748734 1.000 rs4293565 chr2:241834770 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -6.34 -0.49 3.87e-9 Urinary metabolites; TGCT cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.45 -0.5 2.27e-9 Alzheimer's disease; TGCT cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg20637647 chr7:64974828 NA -0.92 -5.09 -0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs17423910 1.000 rs17423605 chr1:66677481 A/G cg04880992 chr1:67434664 MIER1 -0.34 -4.69 -0.39 7.1e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs4285028 0.699 rs12629742 chr3:121614895 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.79 -6.62 -0.51 9.97e-10 Multiple sclerosis; TGCT cis rs2762353 0.718 rs1165160 chr6:25864456 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.45 -4.89 -0.4 3.04e-6 Blood metabolite levels; TGCT cis rs6998277 0.830 rs6468836 chr8:103602630 A/G cg10187029 chr8:103597600 NA 0.56 8.85 0.62 7.44e-15 Migraine; TGCT cis rs236907 0.859 rs2181216 chr1:171744655 A/G cg20598894 chr1:171756153 METTL13 -0.19 -4.51 -0.38 1.46e-5 Mean platelet volume; TGCT cis rs4242434 0.927 rs10099846 chr8:22534178 C/T cg03733263 chr8:22462867 KIAA1967 -1.15 -19.4 -0.87 2.29e-39 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7953508 0.506 rs930316 chr12:93967035 A/G cg18151635 chr12:93972918 NA -0.19 -4.52 -0.38 1.41e-5 Pubertal anthropometrics; TGCT cis rs12421382 0.659 rs11213103 chr11:109385935 A/G cg16359550 chr11:109292809 C11orf87 0.4 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs200259120 1 rs200259120 chr18:9719323 TATAAATAA/T cg24441185 chr18:9708096 RAB31 -0.79 -6.0 -0.47 2.04e-8 Strep throat; TGCT cis rs7681440 0.967 rs6532191 chr4:90745930 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.55 -0.45 1.64e-7 Dementia with Lewy bodies; TGCT cis rs2072499 0.722 rs61462713 chr1:156161682 C/T cg25208724 chr1:156163844 SLC25A44 1.01 9.25 0.64 8.38e-16 Testicular germ cell tumor; TGCT cis rs4746818 1.000 rs10998614 chr10:70923347 G/T cg11621586 chr10:70884670 VPS26A 1.23 10.93 0.7 6.87e-20 Left atrial antero-posterior diameter; TGCT cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg24250549 chr1:154909240 PMVK 0.66 6.5 0.5 1.73e-9 Prostate cancer; TGCT cis rs4680 0.737 rs2239393 chr22:19950428 A/G cg22546130 chr22:19950026 COMT -0.35 -5.25 -0.43 6.47e-7 Blood metabolite levels; TGCT cis rs2153535 0.580 rs1414349 chr6:8472290 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7953249 0.618 rs2650000 chr12:121388962 G/T cg02403541 chr12:121454288 C12orf43 0.66 5.96 0.47 2.45e-8 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs2013441 1.000 rs2165897 chr17:20209721 T/C cg18979559 chr17:20280153 CCDC144C -0.49 -4.99 -0.41 1.97e-6 Obesity-related traits; TGCT cis rs6490294 0.632 rs10849966 chr12:112100773 T/A cg10833066 chr12:111807467 FAM109A 0.34 5.15 0.42 1e-6 Mean platelet volume; TGCT cis rs4788815 0.513 rs12929547 chr16:71794734 A/G cg06353428 chr16:71660113 MARVELD3 1.53 12.17 0.74 6.57e-23 Metabolite levels; TGCT cis rs6450176 0.909 rs3776720 chr5:53296158 A/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs9653442 1.000 rs9653442 chr2:100825367 A/G cg22139774 chr2:100720529 AFF3 0.43 7.68 0.57 4.15e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10504229 0.817 rs35207430 chr8:58167614 G/A cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs2982552 0.844 rs3020347 chr6:152056962 T/G cg22157087 chr6:152012887 ESR1 0.21 5.23 0.43 6.99e-7 Bone properties (heel); TGCT cis rs1799949 0.965 rs35954893 chr17:41333786 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs2075371 0.933 rs2544201 chr7:133963561 C/G cg11752832 chr7:134001865 SLC35B4 0.69 6.1 0.48 1.26e-8 Mean platelet volume; TGCT cis rs9902453 0.904 rs4461132 chr17:28423430 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.31 0.55 2.88e-11 Coffee consumption (cups per day); TGCT cis rs7020830 0.823 rs13285624 chr9:37129496 T/G cg14294708 chr9:37120828 ZCCHC7 1.26 17.63 0.85 1.37e-35 Schizophrenia; TGCT cis rs769267 0.930 rs747050 chr19:19584987 C/G cg08509172 chr19:19383838 TM6SF2 -0.36 -4.67 -0.39 7.66e-6 Tonsillectomy; TGCT cis rs739401 0.595 rs402806 chr11:3066432 A/G cg05729581 chr11:3078854 CARS -0.59 -5.46 -0.44 2.45e-7 Longevity; TGCT cis rs875971 0.862 rs801209 chr7:66019390 G/T cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs782590 0.967 rs1823893 chr2:55788921 T/C cg03859395 chr2:55845619 SMEK2 0.93 11.51 0.72 2.61e-21 Metabolic syndrome; TGCT cis rs12762955 0.561 rs11253567 chr10:1054444 A/G cg20503657 chr10:835505 NA 0.4 5.22 0.42 7.18e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs2180341 0.782 rs6912196 chr6:127722732 C/G cg27446573 chr6:127587934 RNF146 0.8 7.08 0.54 9.53e-11 Breast cancer; TGCT cis rs8177179 0.967 rs6782434 chr3:133438834 C/G cg24879335 chr3:133465180 TF 0.37 5.02 0.41 1.72e-6 Iron status biomarkers (transferrin levels); TGCT cis rs2469997 1.000 rs2469999 chr8:120354695 G/A cg00681363 chr8:120844660 TAF2 0.65 4.52 0.38 1.45e-5 Hypertension (SNP x SNP interaction); TGCT cis rs2795502 1.000 rs2795496 chr10:43337842 G/A cg20628663 chr10:43360327 NA -0.45 -6.39 -0.5 3.05e-9 Blood protein levels; TGCT cis rs7089973 0.604 rs12218498 chr10:116578489 T/C cg03647239 chr10:116582469 FAM160B1 0.58 5.31 0.43 4.95e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg26119090 chr2:26468346 HADHA;HADHB -0.97 -7.19 -0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs2073300 1.000 rs6137975 chr20:23461778 A/G cg09953122 chr20:23471693 CST8 0.6 4.71 0.39 6.63e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT trans rs9650657 0.501 rs3021500 chr8:11023997 G/C cg15556689 chr8:8085844 FLJ10661 -0.9 -9.07 -0.63 2.23e-15 Neuroticism; TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg27535305 chr1:53392650 SCP2 -0.28 -5.68 -0.45 9.1e-8 Monocyte count; TGCT cis rs254781 0.505 rs664366 chr5:88055761 A/G cg22951263 chr5:87985283 NA -0.58 -5.73 -0.46 7.2e-8 Intelligence (multi-trait analysis); TGCT cis rs9549260 0.712 rs9532564 chr13:41160579 C/G cg21288729 chr13:41239152 FOXO1 0.65 4.49 0.37 1.61e-5 Red blood cell count; TGCT cis rs854765 0.547 rs9913277 chr17:17919749 G/T cg04398451 chr17:18023971 MYO15A -0.31 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT cis rs2046867 0.568 rs1553376 chr3:72828151 T/C cg25664220 chr3:72788482 NA -0.54 -6.72 -0.52 5.99e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs3780486 0.846 rs7850878 chr9:33126570 A/G cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs2637266 0.905 rs3923669 chr10:78375047 T/C cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT trans rs9951602 0.512 rs9955812 chr18:76650954 T/A cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs7089973 0.604 rs11819372 chr10:116594934 A/G cg03647239 chr10:116582469 FAM160B1 0.61 5.93 0.47 2.79e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7586879 1.000 rs7608185 chr2:25115432 G/C cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs11690935 0.959 rs6758704 chr2:172655097 T/C cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs986417 1.000 rs4901994 chr14:61090202 C/T cg27398547 chr14:60952738 C14orf39 1.57 8.48 0.61 5.63e-14 Gut microbiota (bacterial taxa); TGCT cis rs2836950 0.565 rs7279497 chr21:40531306 A/G cg11890956 chr21:40555474 PSMG1 0.69 6.84 0.52 3.15e-10 Menarche (age at onset); TGCT cis rs9682041 0.932 rs1525362 chr3:170070702 C/T cg07589077 chr3:170072950 NA 0.3 4.87 0.4 3.33e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7819412 0.807 rs9657519 chr8:10945439 A/G cg21775007 chr8:11205619 TDH -0.53 -4.9 -0.4 2.93e-6 Triglycerides; TGCT trans rs7618501 0.633 rs11925192 chr3:50038664 G/A cg21659725 chr3:3221576 CRBN 0.75 9.02 0.63 2.97e-15 Intelligence (multi-trait analysis); TGCT cis rs6089584 0.888 rs2892060 chr20:60617955 G/T cg13665807 chr20:60559372 TAF4 -0.46 -5.0 -0.41 1.92e-6 Body mass index; TGCT cis rs7772486 0.686 rs9403746 chr6:146103768 C/A cg23711669 chr6:146136114 FBXO30 -0.86 -9.74 -0.66 5.4e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.897 rs8128102 chr21:40606414 G/A cg06238570 chr21:40685208 BRWD1 0.68 6.32 0.49 4.3e-9 Cognitive function; TGCT cis rs6790105 1 rs6790105 chr3:49393409 C/T cg05785598 chr3:49045655 WDR6 0.39 4.65 0.39 8.28e-6 Childhood ear infection; TGCT cis rs1801251 1.000 rs12990821 chr2:233617585 C/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs2721195 0.967 rs748193 chr8:145682115 C/T cg15320075 chr8:145703422 NA 0.7 7.38 0.55 1.99e-11 Age at first birth; TGCT cis rs6500602 0.561 rs62039231 chr16:4519548 A/G cg08645402 chr16:4508243 NA 0.18 4.81 0.4 4.34e-6 Schizophrenia; TGCT cis rs6089829 0.962 rs2277768 chr20:61666823 T/C cg03213289 chr20:61660250 NA 0.7 10.69 0.69 2.64e-19 Prostate cancer (SNP x SNP interaction); TGCT cis rs12497850 0.864 rs12493001 chr3:49181885 A/G cg07636037 chr3:49044803 WDR6 0.94 9.88 0.66 2.51e-17 Parkinson's disease; TGCT cis rs9611565 0.512 rs4822052 chr22:42193741 G/A cg06481639 chr22:41940642 POLR3H -0.66 -6.02 -0.48 1.87e-8 Vitiligo; TGCT cis rs12477438 0.520 rs13009147 chr2:99803998 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs807669 0.903 rs1780642 chr22:19170604 T/C cg02655711 chr22:19163373 SLC25A1 0.42 10.01 0.67 1.23e-17 Metabolite levels; TGCT cis rs6860806 1.000 rs6860806 chr5:131640536 C/T cg24060327 chr5:131705240 SLC22A5 0.6 6.64 0.51 9e-10 Breast cancer; TGCT cis rs11190604 1.000 rs4919468 chr10:102288343 G/C cg23241863 chr10:102295624 HIF1AN 0.66 4.87 0.4 3.38e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3820068 0.603 rs6660234 chr1:15962590 T/C cg05660106 chr1:15850417 CASP9 0.83 8.19 0.59 2.78e-13 Systolic blood pressure; TGCT trans rs916888 0.610 rs199444 chr17:44818276 T/C cg01341218 chr17:43662625 NA 0.85 7.37 0.55 2.11e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4478858 0.806 rs6686845 chr1:31708796 A/T cg00250761 chr1:31883323 NA -0.34 -6.25 -0.49 5.94e-9 Alcohol dependence; TGCT cis rs2282802 0.711 rs3777095 chr5:139660916 G/A cg01081189 chr5:139537190 NA 0.28 5.06 0.41 1.46e-6 Intelligence (multi-trait analysis); TGCT cis rs4478858 0.735 rs11590120 chr1:31792324 A/G cg07478791 chr1:31886160 SERINC2 -0.47 -4.52 -0.38 1.43e-5 Alcohol dependence; TGCT cis rs801193 1.000 rs13239306 chr7:66136017 T/G cg18876405 chr7:65276391 NA -0.35 -5.1 -0.42 1.24e-6 Aortic root size; TGCT cis rs4478858 0.684 rs2050816 chr1:31721708 G/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.89 -0.4 3.11e-6 Alcohol dependence; TGCT cis rs700651 0.757 rs6748683 chr2:198878008 T/A cg00792783 chr2:198669748 PLCL1 0.59 5.27 0.43 5.72e-7 Intracranial aneurysm; TGCT cis rs611744 0.625 rs11779824 chr8:109278689 G/A cg21045802 chr8:109455806 TTC35 0.72 7.44 0.56 1.46e-11 Dupuytren's disease; TGCT cis rs651907 0.557 rs7651721 chr3:101393583 C/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs7147624 0.938 rs7151148 chr14:65936665 G/C cg03016385 chr14:66212404 NA -0.5 -7.18 -0.54 5.64e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7666738 0.515 rs13142498 chr4:98792443 G/T cg17366294 chr4:99064904 C4orf37 0.62 5.78 0.46 5.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10791323 0.569 rs2257004 chr11:133712473 C/T cg15485101 chr11:133734466 NA 0.4 5.27 0.43 5.83e-7 Childhood ear infection; TGCT cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg06238570 chr21:40685208 BRWD1 -0.84 -9.31 -0.64 6.01e-16 Cognitive function; TGCT cis rs1552244 0.572 rs7645759 chr3:10157368 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.11 -0.48 1.16e-8 Alzheimer's disease; TGCT cis rs7772486 0.754 rs13214277 chr6:146136125 G/T cg23711669 chr6:146136114 FBXO30 0.94 10.7 0.69 2.56e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 1.000 rs9467796 chr6:26568411 A/G cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.808 rs7601093 chr2:43710807 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -5.26 -0.43 6.23e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2204008 0.837 rs4312131 chr12:38181087 G/T cg26384229 chr12:38710491 ALG10B 0.86 7.65 0.57 4.87e-12 Bladder cancer; TGCT cis rs66573146 1.000 rs28729690 chr4:6962061 C/T cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs35306767 0.622 rs66462130 chr10:1022108 C/T cg26597838 chr10:835615 NA 0.58 6.42 0.5 2.64e-9 Eosinophil percentage of granulocytes; TGCT cis rs4862750 0.872 rs6553029 chr4:187876470 G/T cg03452623 chr4:187889614 NA 0.33 4.82 0.4 4.12e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2721195 1.000 rs750472 chr8:145701453 A/C cg15320075 chr8:145703422 NA -0.73 -7.57 -0.56 7.57e-12 Age at first birth; TGCT cis rs2677744 0.626 rs3743452 chr15:91497515 C/T cg01710897 chr15:91497902 RCCD1 -0.33 -4.5 -0.37 1.53e-5 Attention deficit hyperactivity disorder; TGCT cis rs6674176 0.660 rs11210936 chr1:44391438 A/T cg12908607 chr1:44402522 ARTN -0.75 -9.27 -0.64 7.36e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs3816788 0.596 rs4872083 chr8:21770372 C/T cg17168535 chr8:21777572 XPO7 0.75 7.28 0.55 3.29e-11 Lung cancer in ever smokers; TGCT cis rs7267979 0.808 rs84816 chr20:25459919 G/A cg14121845 chr20:25566513 NINL 0.49 5.27 0.43 5.87e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3782455 1.000 rs117139141 chr12:114402939 T/G cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs12681287 0.604 rs71502657 chr8:87478781 T/A cg27223183 chr8:87520930 FAM82B -0.88 -6.22 -0.49 6.84e-9 Caudate activity during reward; TGCT cis rs514406 0.505 rs425520 chr1:53179805 C/G cg08859206 chr1:53392774 SCP2 -0.36 -5.23 -0.42 7.05e-7 Monocyte count; TGCT cis rs4851266 1.000 rs11690335 chr2:100826429 A/G cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs8017423 0.647 rs4904674 chr14:90817412 G/A cg04374321 chr14:90722782 PSMC1 -0.58 -5.73 -0.46 7.04e-8 Mortality in heart failure; TGCT cis rs514406 0.505 rs269290 chr1:53167027 A/T cg25767906 chr1:53392781 SCP2 -0.45 -4.85 -0.4 3.59e-6 Monocyte count; TGCT cis rs9357506 1.000 rs4714926 chr6:46304245 A/G cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.37e-7 Body mass index; TGCT cis rs854765 0.583 rs62064156 chr17:17822480 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.94 0.58 1.04e-12 Total body bone mineral density; TGCT cis rs7772486 0.790 rs9791313 chr6:146266172 T/C cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg06238570 chr21:40685208 BRWD1 0.7 6.46 0.5 2.16e-9 Cognitive function; TGCT cis rs77741769 0.571 rs35905305 chr12:121328082 T/G cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.56e-5 Mean corpuscular volume; TGCT cis rs6964587 1.000 rs7802668 chr7:91648939 A/G cg17063962 chr7:91808500 NA 0.9 9.7 0.66 6.73e-17 Breast cancer; TGCT cis rs9650657 0.707 rs4593498 chr8:10655470 C/G cg27411982 chr8:10470053 RP1L1 -0.24 -5.09 -0.42 1.3e-6 Neuroticism; TGCT trans rs208520 0.661 rs207099 chr6:66796373 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs10465746 0.658 rs980418 chr1:84365653 T/G cg10977910 chr1:84465055 TTLL7 0.68 6.7 0.52 6.46e-10 Obesity-related traits; TGCT cis rs7772486 0.875 rs7766463 chr6:146364453 A/G cg05347473 chr6:146136440 FBXO30 0.56 5.42 0.44 2.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs11122272 0.525 rs2749713 chr1:231537921 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs7267979 1.000 rs884613 chr20:25288505 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3796352 0.527 rs11714793 chr3:52924930 A/G cg12962167 chr3:53033115 SFMBT1 0.43 4.47 0.37 1.73e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6433857 0.536 rs1901750 chr2:181350739 C/T cg23363182 chr2:181467187 NA -0.32 -4.85 -0.4 3.59e-6 Body mass index; TGCT cis rs2370759 1.000 rs79442609 chr10:32608749 C/T cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs3820068 0.705 rs41270255 chr1:15892980 G/A cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs700651 0.789 rs1976772 chr2:198868201 G/T cg00792783 chr2:198669748 PLCL1 0.6 5.33 0.43 4.39e-7 Intracranial aneurysm; TGCT cis rs1008375 0.966 rs3796812 chr4:17582051 G/A cg16339924 chr4:17578868 LAP3 0.75 6.67 0.51 7.4e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7590720 1.000 rs934156 chr2:216901482 C/T cg12620499 chr2:216877984 MREG -0.83 -8.13 -0.59 3.65e-13 Alcohol dependence; TGCT cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg18654377 chr3:49208889 KLHDC8B -0.38 -5.03 -0.41 1.69e-6 Menarche (age at onset); TGCT cis rs7584330 0.554 rs3751107 chr2:238427251 G/A cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs7226408 0.857 rs72890516 chr18:34591601 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs3771570 0.901 rs55811034 chr2:242406245 C/T cg21155796 chr2:242212141 HDLBP 0.93 6.69 0.52 6.74e-10 Prostate cancer; TGCT cis rs1215050 0.547 rs10017524 chr4:98588142 C/T cg05340658 chr4:99064831 C4orf37 -0.38 -4.49 -0.37 1.59e-5 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6952808 0.792 rs4421257 chr7:1955152 T/C cg04267008 chr7:1944627 MAD1L1 -0.37 -4.93 -0.4 2.58e-6 Bipolar disorder and schizophrenia; TGCT cis rs17001868 0.568 rs9607699 chr22:40737036 G/A cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs34065801 0.584 rs1171086 chr13:36512158 G/A cg03563146 chr13:37393157 RFXAP -0.48 -4.49 -0.37 1.6e-5 Breast size; TGCT cis rs597539 0.521 rs7943745 chr11:68605828 A/G cg21862992 chr11:68658383 NA -0.34 -4.75 -0.39 5.64e-6 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9611565 0.559 rs13056262 chr22:42081921 A/G cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Vitiligo; TGCT cis rs797680 0.789 rs531514 chr1:93700212 C/T cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9303401 0.659 rs7210432 chr17:56668170 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs3617 0.573 rs9850563 chr3:52912214 G/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.52 -4.98 -0.41 2.06e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7523273 1.000 rs12410786 chr1:207976205 T/A cg22525895 chr1:207977042 MIR29B2 -0.49 -8.66 -0.61 2.07e-14 Schizophrenia; TGCT cis rs12497850 0.931 rs4072859 chr3:49032205 G/C cg18654377 chr3:49208889 KLHDC8B -0.42 -5.43 -0.44 2.85e-7 Parkinson's disease; TGCT cis rs9611565 0.559 rs7290990 chr22:41964357 C/A cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs10927875 0.722 rs6660685 chr1:16346988 A/G cg22431228 chr1:16359049 CLCNKA -0.25 -4.64 -0.38 8.84e-6 Dilated cardiomyopathy; TGCT cis rs1541995 0.792 rs12903841 chr15:96239277 G/A cg00882281 chr15:96346592 NA 0.3 4.82 0.4 4.07e-6 Photic sneeze reflex; TGCT cis rs6988636 1.000 rs59601467 chr8:124193488 C/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs1348850 0.914 rs4893950 chr2:178304885 T/C cg22681709 chr2:178499509 PDE11A -0.35 -4.5 -0.37 1.54e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg05785598 chr3:49045655 WDR6 0.36 4.78 0.39 4.78e-6 Menarche (age at onset); TGCT cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg20637647 chr7:64974828 NA 0.88 5.12 0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs17376456 0.569 rs10476520 chr5:93058290 A/C cg25358565 chr5:93447407 FAM172A 0.76 6.68 0.51 7.23e-10 Diabetic retinopathy; TGCT cis rs3096299 0.738 rs9929606 chr16:89527537 C/T cg08392591 chr16:89556376 ANKRD11 0.54 4.75 0.39 5.63e-6 Multiple myeloma (IgH translocation); TGCT cis rs801193 0.935 rs2659899 chr7:66186721 A/G cg18876405 chr7:65276391 NA 0.35 5.2 0.42 7.81e-7 Aortic root size; TGCT cis rs6671200 0.541 rs3738170 chr1:95699604 G/C cg26537280 chr1:95699037 RWDD3 -0.51 -4.73 -0.39 6.03e-6 Stearic acid (18:0) levels; TGCT cis rs12776158 0.901 rs56979471 chr10:71216760 G/A cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs7681440 1.000 rs1471483 chr4:90754292 A/G cg26578617 chr4:90757533 SNCA -0.47 -4.69 -0.39 6.97e-6 Dementia with Lewy bodies; TGCT cis rs7631605 0.905 rs61489663 chr3:37261734 T/A cg17445812 chr3:36986805 TRANK1 0.21 4.66 0.39 8.17e-6 Cerebrospinal P-tau181p levels; TGCT cis rs74181299 0.964 rs1009358 chr2:65276452 C/T cg05010058 chr2:65284262 CEP68 -0.43 -4.97 -0.41 2.15e-6 Pulse pressure; TGCT cis rs2657888 1.000 rs2657890 chr12:56938577 C/T cg23002907 chr12:56915593 RBMS2 0.38 5.24 0.43 6.83e-7 Adiponectin levels; TGCT cis rs769267 0.930 rs892022 chr19:19613381 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.65 5.44 0.44 2.74e-7 Tonsillectomy; TGCT cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs7010267 0.572 rs2450083 chr8:120063542 T/C cg17171407 chr8:119960777 TNFRSF11B 0.29 5.42 0.44 2.98e-7 Total body bone mineral density (age 45-60); TGCT cis rs7568458 0.660 rs2289972 chr2:85766545 C/T cg17127132 chr2:85788382 GGCX 0.52 4.63 0.38 9.19e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs17376456 0.877 rs10060160 chr5:93387879 G/A cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs9399135 0.967 rs9389258 chr6:135361140 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.28e-6 Red blood cell count; TGCT cis rs10832963 0.594 rs1550869 chr11:18613498 G/T cg09201001 chr11:18656081 SPTY2D1 0.68 6.31 0.49 4.43e-9 Breast cancer; TGCT cis rs6969780 1.000 rs1801085 chr7:27168590 A/G cg04321618 chr7:27170880 HOXA4 0.52 4.59 0.38 1.08e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs514406 0.758 rs532242 chr1:53308665 C/G cg16325326 chr1:53192061 ZYG11B 0.7 8.39 0.6 9.13e-14 Monocyte count; TGCT cis rs854765 0.619 rs6502636 chr17:17983817 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.68 7.01 0.53 1.33e-10 Total body bone mineral density; TGCT cis rs59197085 0.748 rs62479619 chr7:128463864 G/A cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs4820539 0.502 rs4820543 chr22:23542535 A/G cg14186256 chr22:23484241 RTDR1 0.81 8.41 0.6 8.08e-14 Bone mineral density; TGCT cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Vitiligo; TGCT cis rs9467711 0.659 rs13220261 chr6:26499185 C/T cg16898833 chr6:26189333 HIST1H4D 1.24 5.61 0.45 1.26e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs8062405 0.754 rs151179 chr16:28487056 A/G cg09754948 chr16:28834200 ATXN2L 0.6 4.66 0.39 8.02e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9611565 0.512 rs139566 chr22:42199277 A/G cg06634786 chr22:41940651 POLR3H -0.84 -7.7 -0.57 3.66e-12 Vitiligo; TGCT cis rs7542091 0.739 rs10863793 chr1:210037420 G/A cg23283495 chr1:209979779 IRF6 0.49 4.82 0.4 4.15e-6 Monobrow; TGCT cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9640161 0.789 rs3735174 chr7:150020489 T/C cg10018233 chr7:150070692 REPIN1 0.32 4.65 0.39 8.41e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs751728 0.865 rs751726 chr6:33764386 G/A cg13859433 chr6:33739653 LEMD2 -0.39 -7.08 -0.54 9.45e-11 Crohn's disease; TGCT cis rs7647973 0.925 rs11130183 chr3:49228946 A/G cg05785598 chr3:49045655 WDR6 0.38 4.68 0.39 7.48e-6 Menarche (age at onset); TGCT cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg00149659 chr3:10157352 C3orf10 1.05 5.81 0.46 4.95e-8 Alzheimer's disease; TGCT cis rs4727027 0.901 rs34201592 chr7:148842403 C/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.55 0.38 1.25e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs586688 1.000 rs571723 chr1:201642628 C/G cg05779441 chr1:201574716 NA 0.29 4.69 0.39 7.2e-6 Obesity-related traits; TGCT cis rs4919669 0.777 rs10883765 chr10:104456686 T/C cg05855489 chr10:104503620 C10orf26 0.73 4.45 0.37 1.91e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs9357506 0.935 rs1345056 chr6:46306707 A/G cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs11252926 0.574 rs7068976 chr10:453112 A/G cg20256804 chr10:444983 DIP2C -0.21 -4.45 -0.37 1.88e-5 Psychosis in Alzheimer's disease; TGCT cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT trans rs2688608 0.620 rs7098444 chr10:75580042 C/T cg13918328 chr10:52500089 ASAH2B 0.7 7.07 0.54 9.81e-11 Inflammatory bowel disease; TGCT cis rs9467773 1.000 rs9467778 chr6:26534743 T/C cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.821 rs3181073 chr20:30307199 A/C cg13852791 chr20:30311386 BCL2L1 -0.78 -5.8 -0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs2549003 1.000 rs2548997 chr5:131835395 C/T cg02551604 chr5:131831745 NA 0.85 10.91 0.7 7.6e-20 Asthma (sex interaction); TGCT cis rs10892173 0.716 rs12792357 chr11:117666595 C/T cg21640587 chr11:117668038 DSCAML1 0.46 5.1 0.42 1.23e-6 Myopia; TGCT cis rs3780378 0.935 rs2230724 chr9:5081780 G/A cg03508284 chr9:4985524 JAK2 -0.47 -4.44 -0.37 1.97e-5 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs4506170 0.943 rs72712308 chr8:128333220 T/C cg07795030 chr8:128802207 NA -0.21 -4.56 -0.38 1.23e-5 Prostate cancer; TGCT cis rs9400467 0.537 rs73530952 chr6:111486242 G/A cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs11190604 1.000 rs1080698 chr10:102295114 G/T cg16342193 chr10:102329863 NA -0.44 -5.68 -0.45 8.88e-8 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2013441 0.965 rs2703820 chr17:20121479 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs514406 0.607 rs1930305 chr1:53195481 G/T cg01802117 chr1:53393560 SCP2 0.42 4.92 0.4 2.69e-6 Monocyte count; TGCT cis rs2594989 0.887 rs2442799 chr3:11488640 A/G cg00170343 chr3:11313890 ATG7 0.68 4.99 0.41 2.01e-6 Circulating chemerin levels; TGCT cis rs539096 0.831 rs650729 chr1:44042539 C/G cg12908607 chr1:44402522 ARTN -0.5 -5.21 -0.42 7.49e-7 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.581 rs72645895 chr1:15931709 G/A cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.38 5.08 0.42 1.33e-6 Lymphocyte counts; TGCT cis rs3733585 0.699 rs60045583 chr4:9971950 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.62 -0.56 5.57e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8072100 0.676 rs9905308 chr17:45409386 T/A cg08085267 chr17:45401833 C17orf57 -0.51 -5.66 -0.45 9.97e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7208859 0.673 rs73277978 chr17:29191449 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2708977 0.901 rs2579505 chr2:97167962 T/C cg01950434 chr2:97203154 ARID5A -0.7 -6.37 -0.5 3.44e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs2235642 0.928 rs9932984 chr16:1605051 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.74 -0.39 5.81e-6 Coronary artery disease; TGCT cis rs2688608 0.967 rs1815076 chr10:75659886 C/T cg19442545 chr10:75533431 FUT11 -0.3 -4.86 -0.4 3.55e-6 Inflammatory bowel disease; TGCT cis rs67072384 0.818 rs2291292 chr11:72467013 C/T cg03713592 chr11:72463424 ARAP1 -0.96 -4.79 -0.4 4.71e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs9291683 0.507 rs6845554 chr4:10013173 T/G cg11266682 chr4:10021025 SLC2A9 0.69 9.24 0.64 8.6e-16 Bone mineral density; TGCT cis rs10193935 0.901 rs222463 chr2:42644080 A/G cg27598129 chr2:42591480 NA -0.32 -4.65 -0.39 8.33e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8017423 0.967 rs2277514 chr14:90723059 T/C cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs7772486 0.681 rs9390343 chr6:146010527 A/T cg23711669 chr6:146136114 FBXO30 -0.81 -8.65 -0.61 2.25e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs6840360 0.615 rs9884167 chr4:152470799 A/G cg17479576 chr4:152424074 FAM160A1 -0.72 -7.96 -0.58 9.32e-13 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs861020 0.606 rs695140 chr1:210005061 G/A cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs6138458 0.828 rs6132785 chr20:24993414 T/C cg26195577 chr20:24973756 C20orf3 1.04 9.62 0.65 1.04e-16 Blood protein levels; TGCT cis rs6088580 0.634 rs6120669 chr20:33105028 T/C cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs1552244 1.000 rs6781811 chr3:10121922 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.83 -5.65 -0.45 1.05e-7 Alzheimer's disease; TGCT trans rs114540395 0.858 rs116952915 chr10:103265796 C/T cg10198749 chr1:39920707 MACF1 0.55 7.12 0.54 7.73e-11 Schizophrenia; TGCT cis rs9640161 0.702 rs1962004 chr7:150020381 G/A cg10018233 chr7:150070692 REPIN1 0.32 4.58 0.38 1.09e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs13108904 0.935 rs6853002 chr4:1295991 C/T cg03303774 chr4:1407052 NA 0.32 4.78 0.39 4.94e-6 Obesity-related traits; TGCT cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.17 -0.42 9.08e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9677476 1.000 rs6704770 chr2:232109816 T/G cg07929768 chr2:232055508 NA 0.3 4.48 0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs7727544 0.557 rs715285 chr5:131485383 A/G cg24060327 chr5:131705240 SLC22A5 -0.47 -4.74 -0.39 5.66e-6 Blood metabolite levels; TGCT cis rs68170813 0.559 rs5002976 chr7:107050620 C/G cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs2072499 0.898 rs2758609 chr1:156202868 G/A cg06970220 chr1:156163860 SLC25A44 0.71 5.87 0.47 3.81e-8 Testicular germ cell tumor; TGCT cis rs12220238 1.000 rs8255 chr10:75879750 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.94 0.58 1.02e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs910316 0.934 rs8006587 chr14:75664939 A/G cg11812906 chr14:75593930 NEK9 0.74 6.83 0.52 3.46e-10 Height; TGCT cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.23e-17 Electroencephalogram traits; TGCT cis rs12142240 0.698 rs61519400 chr1:46855298 A/G cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg11965913 chr1:205819406 PM20D1 0.53 7.54 0.56 8.56e-12 Menarche (age at onset); TGCT cis rs4889855 0.585 rs17848706 chr17:78704618 G/T cg16591659 chr17:78472290 NA 0.31 4.69 0.39 7.21e-6 Fractional excretion of uric acid; TGCT cis rs7267979 1.000 rs397119 chr20:25440187 C/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs116095464 0.558 rs1541822 chr5:269234 A/C cg12570787 chr5:219185 SDHA;CCDC127 -0.7 -4.7 -0.39 6.83e-6 Breast cancer; TGCT cis rs875971 0.895 rs4718349 chr7:65909011 C/G cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.12e-6 Aortic root size; TGCT cis rs1008375 0.966 rs2010053 chr4:17583806 A/C cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg02353165 chr6:42928485 GNMT 1.07 12.13 0.74 8.27e-23 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs9650657 0.572 rs11250098 chr8:10818607 A/G cg06636001 chr8:8085503 FLJ10661 -0.86 -8.31 -0.6 1.44e-13 Neuroticism; TGCT cis rs11711311 0.784 rs13081931 chr3:113349928 G/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.03 -0.48 1.71e-8 IgG glycosylation; TGCT cis rs4824093 0.610 rs58671506 chr22:50288983 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -6.76 -0.52 4.86e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs12753569 0.748 rs6668566 chr1:76507675 C/G cg00791851 chr1:76518896 NA 0.36 4.65 0.39 8.34e-6 Personality dimensions; TGCT cis rs1857353 1.000 rs10493575 chr1:75903516 G/A cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7666738 0.830 rs4699598 chr4:99019158 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.8 0.4 4.49e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs28451101 chr4:99001190 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs526231 0.543 rs6880911 chr5:102307471 T/C cg23492399 chr5:102201601 PAM -0.53 -4.56 -0.38 1.23e-5 Primary biliary cholangitis; TGCT cis rs9527 0.590 rs7901197 chr10:104840433 C/T cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT cis rs12477438 0.520 rs11123765 chr2:99768064 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.05 0.63 2.42e-15 Chronic sinus infection; TGCT cis rs7937682 0.924 rs10891283 chr11:111527672 A/G cg09085632 chr11:111637200 PPP2R1B -1.12 -11.81 -0.73 4.86e-22 Primary sclerosing cholangitis; TGCT cis rs6894249 1.000 rs6894249 chr5:131797547 A/G cg02551604 chr5:131831745 NA -0.53 -5.01 -0.41 1.85e-6 Asthma; TGCT cis rs72843506 0.722 rs74255387 chr17:20101383 G/A cg18979559 chr17:20280153 CCDC144C -0.71 -5.1 -0.42 1.26e-6 Schizophrenia; TGCT cis rs367615 0.959 rs4957830 chr5:108911758 G/T cg17395555 chr5:108820864 NA 0.29 4.6 0.38 1.04e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs8177253 0.761 rs12490148 chr3:133523973 C/T cg08048268 chr3:133502702 NA -0.73 -11.42 -0.72 4.54e-21 Iron status biomarkers; TGCT cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg22920501 chr2:26401640 FAM59B -0.81 -6.36 -0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs9341808 0.527 rs2505946 chr6:80810683 A/G cg08355045 chr6:80787529 NA 0.34 6.13 0.48 1.07e-8 Sitting height ratio; TGCT cis rs9372498 0.706 rs9489396 chr6:118761703 A/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs7216064 0.531 rs62084683 chr17:66031725 A/G cg12091567 chr17:66097778 LOC651250 1.07 8.8 0.62 9.68e-15 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs12210905 1.000 rs12210905 chr6:27151309 A/G cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs7208859 0.623 rs55814012 chr17:29077697 T/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3087591 0.708 rs2854320 chr17:29694063 C/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.55 0.45 1.65e-7 Hip circumference; TGCT cis rs2980439 0.818 rs2945249 chr8:8094726 G/A cg15462221 chr8:8086144 FLJ10661 -0.56 -5.32 -0.43 4.74e-7 Neuroticism; TGCT cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9807989 0.839 rs9808453 chr2:102971306 C/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs1799949 0.931 rs9912203 chr17:41445145 A/G cg19454999 chr17:41278357 BRCA1;NBR2 -0.45 -4.84 -0.4 3.81e-6 Menopause (age at onset); TGCT cis rs899997 0.773 rs11072783 chr15:78965966 G/A cg00061860 chr15:78953028 NA -0.33 -5.21 -0.42 7.75e-7 Coronary artery disease or large artery stroke; TGCT cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs6089829 0.962 rs6062778 chr20:61663959 A/G cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs12908161 0.959 rs2175567 chr15:85200946 C/G cg17173187 chr15:85201210 NMB 0.6 6.74 0.52 5.37e-10 Schizophrenia; TGCT cis rs4665809 0.590 rs7586047 chr2:26447335 A/G cg25036284 chr2:26402008 FAM59B -0.62 -4.9 -0.4 2.94e-6 Gut microbiome composition (summer); TGCT cis rs12477438 0.501 rs9941561 chr2:99753829 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs2439831 0.702 rs3784275 chr15:44091386 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.86 5.35 0.43 4.02e-7 Lung cancer in ever smokers; TGCT cis rs3806843 0.868 rs2563291 chr5:140119599 T/A cg19875535 chr5:140030758 IK -0.35 -5.94 -0.47 2.67e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs71435601 0.600 rs560844 chr2:21389108 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs10791097 0.547 rs3829271 chr11:130753912 T/A cg05962950 chr11:130786565 SNX19 0.94 11.87 0.73 3.48e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9326248 0.817 rs1242127 chr11:117076564 A/G cg26566898 chr11:117069891 TAGLN -0.34 -4.98 -0.41 2.06e-6 Blood protein levels; TGCT cis rs854765 0.693 rs11657074 chr17:17770355 G/A cg04398451 chr17:18023971 MYO15A 0.29 4.56 0.38 1.19e-5 Total body bone mineral density; TGCT cis rs57920188 0.584 rs12080562 chr1:4089697 C/A cg20703997 chr1:4087676 NA 0.49 6.12 0.48 1.11e-8 Interleukin-17 levels; TGCT trans rs7698623 0.850 rs4693894 chr4:88797798 C/T cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs6866344 0.661 rs72812606 chr5:178129094 A/T cg03877680 chr5:178157825 ZNF354A 0.72 5.65 0.45 1.05e-7 Neutrophil percentage of white cells; TGCT cis rs986417 0.901 rs11627533 chr14:61037801 C/T cg27398547 chr14:60952738 C14orf39 1.62 10.36 0.68 1.69e-18 Gut microbiota (bacterial taxa); TGCT cis rs929354 0.772 rs3802126 chr7:156970281 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs12908161 0.960 rs62019463 chr15:85288087 G/A cg17173187 chr15:85201210 NMB 0.57 6.38 0.5 3.25e-9 Schizophrenia; TGCT cis rs4455778 0.724 rs993872 chr7:48993694 T/G cg26309511 chr7:48887640 NA -0.49 -5.95 -0.47 2.51e-8 Lung cancer in never smokers; TGCT cis rs782590 0.774 rs782632 chr2:55898290 C/G cg18811423 chr2:55921094 PNPT1 0.65 6.76 0.52 4.79e-10 Metabolic syndrome; TGCT cis rs514406 0.644 rs928451 chr1:53195800 A/G cg25767906 chr1:53392781 SCP2 0.44 4.79 0.4 4.68e-6 Monocyte count; TGCT cis rs910316 1.000 rs10142626 chr14:75555636 A/T cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs4253772 0.591 rs11703435 chr22:46685563 C/T cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs75686122 0.892 rs2388725 chr8:104633089 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9915657 0.966 rs1042673 chr17:70121339 A/G cg06234051 chr17:70120541 SOX9 -0.29 -5.62 -0.45 1.17e-7 Thyroid hormone levels; TGCT cis rs16865717 1.000 rs12989595 chr2:7029483 A/G cg20486407 chr2:7037101 RSAD2 0.39 5.18 0.42 8.8e-7 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs587847 0.737 rs2069194 chr15:37665211 G/A cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs644799 0.932 rs10831447 chr11:95663017 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.96 -7.37 -0.55 2.08e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6912958 0.559 rs451829 chr6:88041919 A/G cg10393598 chr6:87862264 NA -0.31 -4.5 -0.37 1.55e-5 Monocyte percentage of white cells; TGCT cis rs6840360 0.571 rs62327270 chr4:152533618 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs4665809 1.000 rs12471809 chr2:26307140 A/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs9611565 0.512 rs1534932 chr22:42150146 C/T cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs4886920 0.518 rs4624137 chr15:78078903 A/G cg03457338 chr15:78040120 NA 0.24 5.28 0.43 5.48e-7 Neuroticism; TGCT cis rs2841277 0.676 rs10438246 chr14:105410183 T/C cg21017887 chr14:105400489 NA 0.36 5.15 0.42 9.89e-7 Rheumatoid arthritis; TGCT cis rs7772486 0.686 rs9376961 chr6:146048737 C/T cg23711669 chr6:146136114 FBXO30 0.85 9.68 0.66 7.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10791097 0.547 rs11222371 chr11:130745719 C/T cg05962950 chr11:130786565 SNX19 0.93 11.63 0.72 1.37e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs2727020 0.558 rs1164675 chr11:49325972 C/T cg03929089 chr4:120376271 NA 0.65 6.89 0.53 2.46e-10 Coronary artery disease; TGCT cis rs1552244 1.000 rs6768102 chr3:10149380 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -6.56 -0.51 1.28e-9 Alzheimer's disease; TGCT cis rs8074700 0.518 rs9646424 chr17:46705605 C/A cg05487507 chr17:46671861 LOC404266;HOXB5 0.45 4.99 0.41 2.03e-6 Body mass index in non-asthmatics; TGCT cis rs9611565 0.659 rs9607813 chr22:41941479 G/A cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs2455799 0.573 rs2470520 chr3:15762920 C/T cg16303742 chr3:15540471 COLQ -0.26 -4.96 -0.41 2.26e-6 Mean platelet volume; TGCT cis rs55962025 0.842 rs362267 chr4:3243218 C/T cg06533319 chr4:3265114 C4orf44 0.23 4.44 0.37 2e-5 Parental longevity (mother's age at death); TGCT cis rs9467711 0.606 rs34622023 chr6:26362119 A/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg11890956 chr21:40555474 PSMG1 -0.69 -6.79 -0.52 4.22e-10 Menarche (age at onset); TGCT cis rs10197940 0.662 rs4592848 chr2:152337822 G/A cg19508488 chr2:152266495 RIF1 0.72 6.58 0.51 1.2e-9 Lung cancer; TGCT cis rs111803315 0.661 rs111876050 chr14:59994667 T/C cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg05738196 chr6:26577821 NA 0.49 4.71 0.39 6.42e-6 Schizophrenia; TGCT cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs34244876 chr4:99031336 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8017423 0.647 rs4904679 chr14:90821801 C/T cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs4919044 0.808 rs7895700 chr10:94791099 A/G cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs7095607 1.000 rs7081213 chr10:69954290 G/A cg18986048 chr10:69913749 MYPN 0.46 4.93 0.41 2.54e-6 Lung function (FVC); TGCT cis rs11741688 0.557 rs6897783 chr5:178330574 G/A cg08270223 chr5:178322770 ZFP2 -0.37 -5.49 -0.44 2.14e-7 Sleep duration; TGCT cis rs6540559 0.546 rs74991018 chr1:210033790 T/G cg04352962 chr1:209979756 IRF6 0.69 4.73 0.39 6.04e-6 Cleft lip with or without cleft palate; TGCT cis rs2075671 0.903 rs11520986 chr7:100276994 A/G cg20848291 chr7:100343083 ZAN -0.52 -4.56 -0.38 1.21e-5 Other erythrocyte phenotypes; TGCT cis rs1372520 0.684 rs2583979 chr4:90750588 A/T cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs7666738 0.830 rs11944035 chr4:98931618 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4786125 0.920 rs6500851 chr16:6896521 A/G cg03623568 chr16:6915990 A2BP1 -0.35 -4.76 -0.39 5.25e-6 Heart rate variability traits (SDNN); TGCT cis rs4285028 0.747 rs3772126 chr3:121354583 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.93 -7.37 -0.55 2.1e-11 Multiple sclerosis; TGCT cis rs7833790 0.654 rs7835342 chr8:82698092 A/G cg27398817 chr8:82754497 SNX16 -0.58 -4.66 -0.39 8.19e-6 Diastolic blood pressure; TGCT cis rs7959452 0.640 rs10878957 chr12:69699638 G/C cg14784868 chr12:69753453 YEATS4 0.68 6.93 0.53 2.03e-10 Blood protein levels; TGCT cis rs9393777 0.513 rs9393741 chr6:26654189 A/G cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs6831352 0.819 rs1230158 chr4:99990186 T/C cg12011299 chr4:100065546 ADH4 0.4 5.46 0.44 2.5e-7 Alcohol dependence; TGCT cis rs9611565 0.659 rs56364401 chr22:41951243 T/G cg06634786 chr22:41940651 POLR3H -0.9 -8.98 -0.63 3.59e-15 Vitiligo; TGCT cis rs10504229 0.683 rs67035623 chr8:58139963 G/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs3008870 1.000 rs3008856 chr1:67387901 T/C cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs11098499 0.954 rs7687843 chr4:120421211 C/T cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs9916302 0.706 rs6503500 chr17:37485925 C/T cg07936489 chr17:37558343 FBXL20 -0.78 -5.83 -0.46 4.59e-8 Glomerular filtration rate (creatinine); TGCT cis rs17376456 0.825 rs35426871 chr5:93291613 C/T cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg17554472 chr22:41940697 POLR3H -0.46 -4.79 -0.39 4.71e-6 Vitiligo; TGCT cis rs7666738 0.822 rs28512427 chr4:98919029 G/A cg17366294 chr4:99064904 C4orf37 0.71 7.25 0.55 3.96e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs8077577 1.000 rs7207276 chr17:18065737 G/C cg09161412 chr17:18057145 MYO15A -0.67 -5.44 -0.44 2.69e-7 Obesity-related traits; TGCT cis rs736801 1.000 rs736801 chr5:131833599 C/T cg02551604 chr5:131831745 NA 0.56 4.57 0.38 1.14e-5 Breast cancer;Mosquito bite size; TGCT cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg03264133 chr6:25882463 NA -0.54 -5.78 -0.46 5.69e-8 Height; TGCT cis rs17376456 0.542 rs35672980 chr5:93284877 A/T cg21475434 chr5:93447410 FAM172A -0.62 -5.97 -0.47 2.3e-8 Diabetic retinopathy; TGCT cis rs12477438 0.520 rs2516827 chr2:99772565 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs12049351 0.774 rs34405887 chr1:229618634 C/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs9443645 0.869 rs1567168 chr6:79536455 G/T cg09184832 chr6:79620586 NA -0.46 -4.94 -0.41 2.49e-6 Intelligence (multi-trait analysis); TGCT cis rs11250097 0.549 rs11784897 chr8:11310442 G/A cg01383082 chr8:11323474 FAM167A 0.28 4.54 0.38 1.3e-5 Neuroticism; TGCT cis rs7267979 0.549 rs6138536 chr20:25182648 A/G cg14121845 chr20:25566513 NINL 0.43 4.64 0.38 8.62e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12681287 0.511 rs9297923 chr8:87548989 T/C cg27223183 chr8:87520930 FAM82B 0.94 6.91 0.53 2.24e-10 Caudate activity during reward; TGCT cis rs6570726 0.791 rs370654 chr6:145879005 C/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg16145915 chr7:1198662 ZFAND2A -0.6 -8.54 -0.61 4.04e-14 Longevity;Endometriosis; TGCT cis rs6582630 0.555 rs56228141 chr12:38518652 T/G cg26384229 chr12:38710491 ALG10B 0.84 7.68 0.57 4.16e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs763014 0.865 rs710924 chr16:633353 T/C cg07343612 chr16:622815 PIGQ -0.39 -7.36 -0.55 2.26e-11 Height; TGCT cis rs10504229 0.683 rs6995355 chr8:58113870 C/T cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs6840360 0.571 rs2165789 chr4:152510130 A/T cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs208520 0.690 rs207108 chr6:66794096 T/C cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs3820068 0.581 rs68052904 chr1:15916714 T/C cg05660106 chr1:15850417 CASP9 0.8 8.06 0.59 5.6e-13 Systolic blood pressure; TGCT cis rs2282802 0.660 rs6873248 chr5:139683762 A/G cg01081189 chr5:139537190 NA -0.29 -5.31 -0.43 5e-7 Intelligence (multi-trait analysis); TGCT cis rs9357506 1.000 rs12055407 chr6:46306474 A/G cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs62103177 0.713 rs62103186 chr18:77627574 G/C cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs873946 0.586 rs12776770 chr10:134564831 T/C cg05985448 chr10:134359359 INPP5A 0.22 4.83 0.4 3.89e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7937682 0.883 rs484834 chr11:111465761 G/C cg09085632 chr11:111637200 PPP2R1B -0.99 -9.99 -0.67 1.34e-17 Primary sclerosing cholangitis; TGCT cis rs2692947 0.616 rs2301707 chr2:96931846 T/C cg22654517 chr2:96458247 NA 0.22 4.9 0.4 2.92e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs1949733 0.656 rs2688224 chr4:8404700 C/G cg11789530 chr4:8429930 ACOX3 0.48 4.47 0.37 1.71e-5 Response to antineoplastic agents; TGCT cis rs28386778 0.701 rs2727337 chr17:61991966 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.98 -13.09 -0.76 4.1e-25 Prudent dietary pattern; TGCT cis rs4906332 1.000 rs55930273 chr14:103960298 G/A cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs2456568 0.803 rs10765641 chr11:93640312 T/C cg17595323 chr11:93583763 C11orf90 -0.46 -6.24 -0.49 6.46e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7727544 0.631 rs13357280 chr5:131600187 A/G cg21474247 chr5:131268130 NA 0.3 4.44 0.37 1.94e-5 Blood metabolite levels; TGCT cis rs2224391 0.628 rs2773318 chr6:5258843 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.48 -0.5 1.94e-9 Height; TGCT cis rs11731606 0.508 rs28623728 chr4:95290861 C/T cg00507259 chr4:95128692 SMARCAD1 0.64 4.78 0.39 4.97e-6 Mean platelet volume; TGCT trans rs210152 0.541 rs35432298 chr6:33457013 T/A cg08795360 chr21:41033440 B3GALT5 0.45 7.11 0.54 8.23e-11 Schizophrenia; TGCT cis rs554111 0.634 rs34740989 chr1:21316782 C/T cg01072550 chr1:21505969 NA 0.36 5.43 0.44 2.9e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs950169 0.922 rs11639244 chr15:84832650 G/A cg17173187 chr15:85201210 NMB 0.54 5.52 0.44 1.94e-7 Schizophrenia; TGCT cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg13665807 chr20:60559372 TAF4 -0.5 -5.23 -0.43 6.92e-7 Body mass index; TGCT cis rs4689388 0.926 rs9998835 chr4:6293237 C/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6733011 0.604 rs12712035 chr2:99461298 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -4.75 -0.39 5.58e-6 Bipolar disorder; TGCT cis rs8072100 0.666 rs9913503 chr17:45776330 T/G cg08085267 chr17:45401833 C17orf57 -0.46 -5.17 -0.42 9.01e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7714584 1.000 rs75071288 chr5:150224379 C/T cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs8031584 0.678 rs3122 chr15:31170290 A/T cg14829155 chr15:31115871 NA 0.38 4.82 0.4 4.12e-6 Huntington's disease progression; TGCT cis rs4653767 1.000 rs10495249 chr1:226919119 A/G cg10327440 chr1:227177885 CDC42BPA -0.46 -5.07 -0.41 1.41e-6 Parkinson's disease; TGCT cis rs57221529 0.655 rs72704791 chr5:547896 A/G cg09021430 chr5:549028 NA -0.4 -5.1 -0.42 1.22e-6 Lung disease severity in cystic fibrosis; TGCT cis rs9807989 0.571 rs10208293 chr2:102966310 G/A cg09003973 chr2:102972529 NA 0.83 6.8 0.52 3.98e-10 Asthma; TGCT cis rs10088262 0.629 rs1367829 chr8:124797135 A/G cg02993010 chr8:124780839 FAM91A1 -0.63 -5.13 -0.42 1.08e-6 Pancreatic cancer; TGCT cis rs6089584 0.507 rs6061990 chr20:60628429 T/G cg13665807 chr20:60559372 TAF4 -0.44 -4.77 -0.39 5.09e-6 Body mass index; TGCT cis rs12477438 0.520 rs11123765 chr2:99768064 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.47 0.86 2.08e-37 Chronic sinus infection; TGCT cis rs1153858 1.000 rs12437840 chr15:45669055 C/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs7599312 0.534 rs7607373 chr2:213409719 G/A cg20637307 chr2:213403960 ERBB4 0.91 11.34 0.71 7.02e-21 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1799949 0.860 rs8176279 chr17:41210396 A/C cg05368731 chr17:41323189 NBR1 1.01 10.1 0.67 7.21e-18 Menopause (age at onset); TGCT cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg06640241 chr16:89574553 SPG7 0.77 8.97 0.63 3.82e-15 Multiple myeloma (IgH translocation); TGCT cis rs6831352 1.000 rs6831352 chr4:100063525 T/C cg12011299 chr4:100065546 ADH4 0.42 5.26 0.43 6.06e-7 Alcohol dependence; TGCT cis rs1784581 0.775 rs7755404 chr6:162427731 T/C cg17173639 chr6:162384350 PARK2 0.42 7.38 0.55 2.03e-11 Itch intensity from mosquito bite; TGCT cis rs11779988 0.545 rs10095047 chr8:17750328 T/C cg01800426 chr8:17659068 MTUS1 -0.57 -5.09 -0.42 1.27e-6 Breast cancer; TGCT cis rs10751667 0.666 rs10902239 chr11:946484 A/G cg06064525 chr11:970664 AP2A2 0.35 8.12 0.59 4.04e-13 Alzheimer's disease (late onset); TGCT cis rs1153858 1.000 rs12439274 chr15:45636667 A/G cg26924012 chr15:45694286 SPATA5L1 1.08 14.12 0.79 1.39e-27 Homoarginine levels; TGCT cis rs2235642 0.785 rs1057983 chr16:1660274 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.58 -0.38 1.11e-5 Coronary artery disease; TGCT cis rs2204008 0.774 rs2387811 chr12:38369794 C/A cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.76e-6 Bladder cancer; TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs9660180 0.967 rs12044597 chr1:1708801 A/G cg20999797 chr1:1681921 NA 0.18 4.78 0.39 4.93e-6 Body mass index; TGCT trans rs1814175 0.653 rs10839480 chr11:50034556 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs6690583 0.512 rs7547224 chr1:85456902 T/C cg20280350 chr1:85513789 MCOLN3 -0.79 -5.27 -0.43 5.77e-7 Serum sulfate level; TGCT cis rs10465746 0.780 rs10874423 chr1:84374071 C/T cg10977910 chr1:84465055 TTLL7 0.66 6.65 0.51 8.38e-10 Obesity-related traits; TGCT cis rs2019216 0.542 rs3829569 chr17:21909222 T/C cg22648282 chr17:21454238 C17orf51 -0.56 -5.45 -0.44 2.57e-7 Pelvic organ prolapse; TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs11249608 0.548 rs62393072 chr5:178450056 C/T cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg25703541 chr22:24373054 LOC391322 -0.81 -7.82 -0.57 1.93e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7584330 0.737 rs1497128 chr2:238369211 A/G cg14458575 chr2:238380390 NA 0.49 8.05 0.59 5.71e-13 Prostate cancer; TGCT cis rs1055129 0.655 rs8067076 chr17:73837142 G/T cg10935138 chr17:73851978 WBP2 -0.51 -4.48 -0.37 1.68e-5 White matter hyperintensity burden; TGCT cis rs3785574 0.962 rs2584632 chr17:61880641 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.68 0.45 9.24e-8 Height; TGCT cis rs35146811 0.844 rs4424195 chr7:99642745 A/G cg13334819 chr7:99746414 C7orf59 -0.8 -6.87 -0.52 2.81e-10 Coronary artery disease; TGCT trans rs17471911 0.708 rs6584231 chr10:100784115 G/A cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs9291683 0.588 rs3796829 chr4:10019138 C/G cg02734326 chr4:10020555 SLC2A9 0.38 4.54 0.38 1.34e-5 Bone mineral density; TGCT cis rs17376456 0.757 rs6859757 chr5:93206042 C/T cg25358565 chr5:93447407 FAM172A 0.99 7.65 0.57 4.94e-12 Diabetic retinopathy; TGCT cis rs7639513 0.767 rs9861271 chr3:12707620 A/C cg23032965 chr3:12705835 RAF1 0.77 8.55 0.61 3.81e-14 Itch intensity from mosquito bite; TGCT cis rs11690935 0.959 rs67204065 chr2:172672624 G/A cg13550731 chr2:172543902 DYNC1I2 -1.03 -9.98 -0.67 1.45e-17 Schizophrenia; TGCT cis rs2762353 0.779 rs6905614 chr6:25840485 G/T cg07061783 chr6:25882402 NA -0.43 -4.61 -0.38 9.88e-6 Blood metabolite levels; TGCT cis rs6500602 0.727 rs55939215 chr16:4541390 C/G cg08645402 chr16:4508243 NA 0.18 5.06 0.41 1.44e-6 Schizophrenia; TGCT cis rs2197308 0.619 rs4002730 chr12:37876400 T/C cg26384229 chr12:38710491 ALG10B 0.89 7.98 0.58 8.43e-13 Morning vs. evening chronotype; TGCT cis rs1008375 0.898 rs4698623 chr4:17594702 T/C cg10189774 chr4:17578691 LAP3 0.68 5.74 0.46 6.99e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg07507251 chr3:52567010 NT5DC2 0.46 6.66 0.51 7.92e-10 Bipolar disorder; TGCT cis rs7267979 1.000 rs6083804 chr20:25317060 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12134245 1.000 rs12134245 chr1:92021464 C/T cg02896835 chr1:92012615 NA -0.26 -4.45 -0.37 1.88e-5 Breast cancer; TGCT cis rs9300255 0.566 rs1716169 chr12:123716930 A/T cg00376283 chr12:123451042 ABCB9 0.66 4.59 0.38 1.08e-5 Neutrophil percentage of white cells; TGCT cis rs9611565 0.659 rs11090049 chr22:41915329 C/T cg17554472 chr22:41940697 POLR3H -0.48 -5.15 -0.42 9.89e-7 Vitiligo; TGCT cis rs2836974 0.931 rs2989330 chr21:40716209 A/G cg06238570 chr21:40685208 BRWD1 0.58 4.63 0.38 8.99e-6 Cognitive function; TGCT cis rs3947 0.756 rs1613883 chr8:11699632 T/A cg02840367 chr8:11660030 FDFT1 0.91 6.7 0.52 6.58e-10 Blood protein levels; TGCT cis rs523522 0.962 rs10744752 chr12:120900554 T/G cg27279351 chr12:120934652 DYNLL1 0.76 6.54 0.51 1.46e-9 High light scatter reticulocyte count; TGCT cis rs2204008 0.744 rs11181635 chr12:38378420 C/T cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.76e-6 Bladder cancer; TGCT cis rs5758659 0.504 rs133367 chr22:42463366 A/G cg05082376 chr22:42548792 NA 0.21 5.24 0.43 6.65e-7 Cognitive function; TGCT cis rs2235642 0.750 rs2859310 chr16:1656765 C/T cg08296037 chr16:1584118 IFT140;TMEM204 0.29 4.98 0.41 2.06e-6 Coronary artery disease; TGCT trans rs877282 1.000 rs877282 chr10:771532 G/A cg22713356 chr15:30763199 NA 1.2 10.36 0.68 1.66e-18 Uric acid levels; TGCT cis rs992157 0.560 rs4674275 chr2:219097738 G/A cg00012203 chr2:219082015 ARPC2 -0.81 -9.41 -0.65 3.47e-16 Colorectal cancer; TGCT cis rs2115630 0.936 rs8033459 chr15:85253258 C/T cg24513567 chr15:85260248 SEC11A -0.34 -4.47 -0.37 1.76e-5 P wave terminal force; TGCT cis rs9611519 0.589 rs8138917 chr22:41412425 T/C cg13695892 chr22:41940480 POLR3H -0.55 -5.14 -0.42 1.04e-6 Neuroticism; TGCT cis rs56399783 0.901 rs73049305 chr7:2778755 C/T cg19731401 chr7:2775893 GNA12 0.36 5.07 0.41 1.4e-6 Childhood ear infection; TGCT cis rs2243480 1.000 rs67728539 chr7:65378124 G/A cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs910316 0.726 rs175040 chr14:75469555 A/G cg08847533 chr14:75593920 NEK9 -0.84 -9.11 -0.63 1.75e-15 Height; TGCT cis rs2839186 0.558 rs2968 chr21:47608580 C/T cg13012494 chr21:47604986 C21orf56 -0.41 -5.05 -0.41 1.53e-6 Testicular germ cell tumor; TGCT cis rs801193 0.569 rs10950050 chr7:66239588 A/C cg11764359 chr7:65958608 NA 0.49 4.65 0.39 8.38e-6 Aortic root size; TGCT cis rs617219 0.710 rs2255913 chr5:78562399 G/C cg09550809 chr5:78407562 BHMT 0.37 5.24 0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1372520 0.684 rs2619368 chr4:90729747 T/G cg26578617 chr4:90757533 SNCA -0.52 -4.44 -0.37 1.99e-5 Neuroticism; TGCT cis rs74233809 1.000 rs12219901 chr10:104840967 A/G cg05855489 chr10:104503620 C10orf26 0.79 4.56 0.38 1.19e-5 Birth weight; TGCT cis rs4888262 0.545 rs7184754 chr16:74667864 C/T cg01733217 chr16:74700730 RFWD3 0.73 7.23 0.54 4.25e-11 Testicular germ cell tumor; TGCT cis rs9902453 0.868 rs9890075 chr17:28470464 C/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs514406 0.505 rs395169 chr1:53174071 G/A cg16325326 chr1:53192061 ZYG11B 0.85 11.98 0.73 1.93e-22 Monocyte count; TGCT cis rs1865760 0.663 rs9379815 chr6:25980116 T/A cg16482183 chr6:26056742 HIST1H1C 0.56 5.05 0.41 1.52e-6 Height; TGCT cis rs78487399 0.808 rs116451849 chr2:43662911 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.69 0.39 7.08e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4595586 0.870 rs10876208 chr12:39287667 G/T cg10518543 chr12:38710700 ALG10B -0.47 -4.6 -0.38 1.04e-5 Morning vs. evening chronotype; TGCT cis rs11105298 0.891 rs10858894 chr12:89914261 T/C cg00757033 chr12:89920650 WDR51B 0.34 5.46 0.44 2.52e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6490294 0.583 rs4346023 chr12:112285542 C/T cg10833066 chr12:111807467 FAM109A -0.3 -4.82 -0.4 4.05e-6 Mean platelet volume; TGCT cis rs350251 0.868 rs350278 chr16:12232402 T/C cg02910054 chr16:12241554 SNX29 0.33 4.57 0.38 1.18e-5 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.559 rs451465 chr6:88043372 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.69 -6.99 -0.53 1.48e-10 Monocyte percentage of white cells; TGCT cis rs3540 0.574 rs2256388 chr15:90969335 A/C cg22089800 chr15:90895588 ZNF774 -0.76 -8.15 -0.59 3.42e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs713587 1.000 rs713587 chr2:25158281 C/T cg15423357 chr2:25149977 NA 0.63 6.43 0.5 2.55e-9 Body mass index in non-asthmatics; TGCT cis rs6558530 0.666 rs10113471 chr8:1695827 C/A cg09410841 chr8:1729607 CLN8 0.67 6.0 0.47 2.05e-8 Systolic blood pressure; TGCT cis rs6860806 0.507 rs270614 chr5:131640813 G/A cg24060327 chr5:131705240 SLC22A5 -0.73 -7.65 -0.57 4.87e-12 Breast cancer; TGCT cis rs4595586 0.545 rs1303886 chr12:39366876 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs9300255 0.506 rs11057251 chr12:123791227 A/G cg00376283 chr12:123451042 ABCB9 -0.66 -5.67 -0.45 9.67e-8 Neutrophil percentage of white cells; TGCT cis rs10504229 1.000 rs73609762 chr8:58192695 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9902453 0.791 rs3115090 chr17:28035014 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.85 8.57 0.61 3.4e-14 Coffee consumption (cups per day); TGCT cis rs7826238 0.502 rs10503377 chr8:8378422 C/T cg06636001 chr8:8085503 FLJ10661 0.63 5.17 0.42 9.02e-7 Systolic blood pressure; TGCT cis rs7095607 0.606 rs7095774 chr10:69957554 C/T cg18986048 chr10:69913749 MYPN 0.56 5.87 0.47 3.76e-8 Lung function (FVC); TGCT cis rs6840360 0.607 rs6815320 chr4:152432500 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs939574 1.000 rs908196 chr2:220088248 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.04 -6.48 -0.5 1.91e-9 Platelet distribution width; TGCT cis rs62064224 0.560 rs12162135 chr17:30805795 A/C cg18200150 chr17:30822561 MYO1D 0.53 7.35 0.55 2.33e-11 Schizophrenia; TGCT cis rs4689388 0.889 rs4629534 chr4:6294124 G/T cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7666738 0.830 rs6532721 chr4:99048015 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 1.000 rs2109522 chr4:17658645 T/A cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9330316 0.654 rs3934873 chr2:110286299 G/A cg25199208 chr2:109402912 CCDC138 0.42 4.65 0.39 8.37e-6 Schizophrenia; TGCT cis rs59698941 0.527 rs1557852 chr5:132181800 G/A cg27099455 chr5:132201840 GDF9;UQCRQ 0.29 4.94 0.41 2.52e-6 Apolipoprotein A-IV levels; TGCT cis rs939658 1.000 rs8031504 chr15:79458589 G/T cg17916960 chr15:79447300 NA 0.54 8.64 0.61 2.42e-14 Refractive error; TGCT cis rs854765 0.583 rs4553680 chr17:17857722 A/G cg09796270 chr17:17721594 SREBF1 0.26 5.31 0.43 4.88e-7 Total body bone mineral density; TGCT cis rs13108904 0.710 rs11937232 chr4:1207597 G/C cg05665937 chr4:1216051 CTBP1 0.26 5.16 0.42 9.43e-7 Obesity-related traits; TGCT cis rs7772486 0.727 rs10447449 chr6:146138707 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.9 0.66 2.27e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs4972806 0.814 rs1446575 chr2:177047801 A/C cg14324370 chr2:177042789 NA 0.68 6.49 0.5 1.89e-9 IgG glycosylation; TGCT cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg07424592 chr7:64974309 NA 1.31 8.12 0.59 3.98e-13 Diabetic kidney disease; TGCT cis rs9341808 0.718 rs9448893 chr6:80837239 A/G cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs5769765 0.955 rs5769767 chr22:50276909 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs4700695 0.614 rs251286 chr5:65212769 A/G cg21114390 chr5:65439923 SFRS12 0.68 4.8 0.4 4.54e-6 Facial morphology (factor 19); TGCT cis rs10256972 0.567 rs7782651 chr7:1159895 T/G cg07092213 chr7:1199455 ZFAND2A -0.43 -4.64 -0.38 8.8e-6 Longevity;Endometriosis; TGCT cis rs6547741 0.717 rs2178197 chr2:27860551 C/T cg27432699 chr2:27873401 GPN1 0.24 6.01 0.47 1.96e-8 Oral cavity cancer; TGCT cis rs28595532 1.000 rs116030177 chr4:119650768 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs614226 1.000 rs1167725 chr12:120968559 A/T cg10072921 chr12:121022843 NA -0.44 -4.74 -0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs7312933 0.558 rs55702525 chr12:42814309 T/C cg19980929 chr12:42632907 YAF2 -0.4 -5.7 -0.46 8.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2847281 0.587 rs2542157 chr18:12787247 T/G cg23598886 chr18:12777645 NA 0.37 4.66 0.39 8.02e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs4845570 0.831 rs11588634 chr1:151780686 T/A cg07092448 chr1:151763213 TDRKH -1.17 -8.37 -0.6 1e-13 Coronary artery disease; TGCT cis rs4824093 0.610 rs9627798 chr22:50317857 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.15 -4.45 -0.37 1.86e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9467711 0.790 rs35162296 chr6:26318262 C/T cg05948654 chr6:25930507 SLC17A2 0.34 4.54 0.38 1.29e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6964587 1.000 rs9690778 chr7:91735299 A/G cg22709100 chr7:91322751 NA 0.29 4.79 0.4 4.67e-6 Breast cancer; TGCT cis rs17376456 0.877 rs10055340 chr5:93317644 T/C cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs9393692 0.905 rs6908328 chr6:26292855 C/A cg00631329 chr6:26305371 NA -0.42 -6.22 -0.49 6.83e-9 Educational attainment; TGCT cis rs2730245 0.505 rs2657360 chr7:158673604 A/G cg24397884 chr7:158709396 WDR60 0.37 4.93 0.4 2.63e-6 Height; TGCT cis rs1670533 1.000 rs629261 chr4:1086763 A/C cg27284194 chr4:1044797 NA 0.68 5.95 0.47 2.59e-8 Recombination rate (females); TGCT cis rs1018836 0.663 rs2205152 chr8:91483618 C/T cg16814680 chr8:91681699 NA 0.83 8.39 0.6 9.07e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7772486 0.875 rs2748482 chr6:146336532 T/C cg05347473 chr6:146136440 FBXO30 0.56 5.29 0.43 5.34e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs11690462 0.963 rs2384362 chr2:26630389 A/T cg04726446 chr2:26624865 C2orf39 -0.44 -4.8 -0.4 4.45e-6 Coronary artery disease; TGCT cis rs6831352 0.837 rs2924583 chr4:100044640 T/C cg12011299 chr4:100065546 ADH4 0.41 4.92 0.4 2.72e-6 Alcohol dependence; TGCT cis rs12142240 0.621 rs13374968 chr1:46843908 T/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.51e-8 Menopause (age at onset); TGCT cis rs17490626 0.568 rs12260685 chr10:71215799 C/T cg14388049 chr10:71211838 TSPAN15 -0.39 -4.47 -0.37 1.71e-5 Thrombosis; TGCT cis rs2153535 0.580 rs9406164 chr6:8470048 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs826838 0.935 rs11169508 chr12:39173385 C/T cg13010199 chr12:38710504 ALG10B 0.78 6.16 0.48 9.26e-9 Heart rate; TGCT cis rs9926296 0.744 rs164748 chr16:89708292 C/G cg03388025 chr16:89894329 SPIRE2 -0.34 -5.21 -0.42 7.59e-7 Vitiligo; TGCT cis rs11690935 0.885 rs7602037 chr2:172817794 G/A cg13550731 chr2:172543902 DYNC1I2 -0.89 -7.89 -0.58 1.33e-12 Schizophrenia; TGCT cis rs422249 0.512 rs174576 chr11:61603510 C/A cg01500311 chr11:61656094 FADS3 -0.32 -5.69 -0.46 8.54e-8 Trans fatty acid levels; TGCT cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg23221052 chr5:179740743 GFPT2 -0.35 -5.58 -0.45 1.41e-7 Height; TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg24675658 chr1:53192096 ZYG11B 0.71 8.15 0.59 3.39e-13 Monocyte count; TGCT cis rs7647973 0.626 rs9830730 chr3:49675875 G/C cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs9291683 0.509 rs6849717 chr4:9958719 T/C cg11266682 chr4:10021025 SLC2A9 -0.62 -8.62 -0.61 2.56e-14 Bone mineral density; TGCT cis rs9527 0.590 rs7087459 chr10:104790999 T/C cg04362960 chr10:104952993 NT5C2 0.66 5.57 0.45 1.48e-7 Arsenic metabolism; TGCT cis rs4733781 0.563 rs6985563 chr8:131332344 C/T cg16277922 chr8:131349729 ASAP1 0.43 6.28 0.49 5.19e-9 Tuberculosis; TGCT cis rs6867913 0.709 rs891987 chr5:141467196 A/T cg23435118 chr5:141488016 NDFIP1 0.25 4.63 0.38 9.08e-6 Asthma; TGCT cis rs250677 0.687 rs168750 chr5:148446756 A/G cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs4700695 0.719 rs27584 chr5:65445232 G/A cg21114390 chr5:65439923 SFRS12 -0.84 -7.45 -0.56 1.35e-11 Facial morphology (factor 19); TGCT cis rs11190604 1.000 rs11190599 chr10:102295420 C/T cg16342193 chr10:102329863 NA -0.41 -5.37 -0.43 3.78e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.830 rs34273190 chr4:99004568 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7017914 0.967 rs4628281 chr8:71839164 T/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.52 -4.71 -0.39 6.62e-6 Bone mineral density; TGCT cis rs7666738 0.830 rs7691433 chr4:98968118 A/T cg17366294 chr4:99064904 C4orf37 0.69 6.63 0.51 9.14e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs853679 0.517 rs9368557 chr6:28131537 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs1692580 0.840 rs262679 chr1:2169792 C/T cg21194808 chr1:2205498 SKI 0.28 5.33 0.43 4.44e-7 Coronary artery disease; TGCT cis rs6840360 0.571 rs11939356 chr4:152505234 G/C cg17479576 chr4:152424074 FAM160A1 -0.72 -7.81 -0.57 2.09e-12 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.533 rs4528310 chr11:49983106 C/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs344364 0.529 rs186941 chr16:1930088 T/C cg09830162 chr16:1889614 FAHD1;C16orf73 0.45 5.35 0.43 4.1e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7524258 0.900 rs6670323 chr1:7301947 C/A cg07173049 chr1:7289937 CAMTA1 0.3 4.83 0.4 3.91e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs9467711 0.538 rs9467626 chr6:25873746 C/A cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Autism spectrum disorder or schizophrenia; TGCT trans rs210152 0.588 rs210131 chr6:33535466 T/C cg15679064 chr19:49134105 DBP 1.22 6.8 0.52 4.01e-10 Schizophrenia; TGCT cis rs12541335 0.507 rs9644047 chr8:22158670 T/A cg26039829 chr8:22132926 PIWIL2 0.28 5.17 0.42 9e-7 Hypertriglyceridemia; TGCT cis rs1475911 0.708 rs8129075 chr21:43523430 G/T cg24372256 chr21:43528868 UMODL1;C21orf128 -0.32 -6.07 -0.48 1.47e-8 IgG glycosylation; TGCT cis rs8180040 0.966 rs13079098 chr3:47442863 A/G cg27129171 chr3:47204927 SETD2 0.67 7.78 0.57 2.43e-12 Colorectal cancer; TGCT cis rs9443645 0.901 rs7749916 chr6:79814192 A/G cg09184832 chr6:79620586 NA -0.47 -5.07 -0.41 1.4e-6 Intelligence (multi-trait analysis); TGCT cis rs2075371 0.863 rs2075370 chr7:133967812 A/G cg11752832 chr7:134001865 SLC35B4 0.69 6.1 0.48 1.26e-8 Mean platelet volume; TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg27535305 chr1:53392650 SCP2 -0.28 -5.9 -0.47 3.26e-8 Monocyte count; TGCT cis rs9473924 0.505 rs9473949 chr6:50909659 T/A cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs9858542 0.953 rs10640 chr3:49454277 G/A cg03060546 chr3:49711283 APEH -0.63 -5.55 -0.45 1.67e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs9372498 0.505 rs17080456 chr6:118985938 G/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.71 -0.39 6.4e-6 Diastolic blood pressure; TGCT cis rs6964587 0.626 rs7807765 chr7:91531974 C/A cg17063962 chr7:91808500 NA -0.76 -7.18 -0.54 5.68e-11 Breast cancer; TGCT cis rs2562456 0.917 rs6511256 chr19:21693315 G/T cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs6570726 0.577 rs406868 chr6:145809983 C/T cg13319975 chr6:146136371 FBXO30 -0.64 -5.69 -0.46 8.55e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs17114671 1.000 rs4982326 chr14:21157936 G/A cg19983597 chr14:21852154 SUPT16H 0.84 4.62 0.38 9.54e-6 Blood protein levels; TGCT cis rs13191362 1.000 rs13212608 chr6:163032128 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 4.96 0.41 2.28e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7267979 0.966 rs910996 chr20:25264196 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.508 rs12498066 chr3:52627660 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs10782582 0.532 rs78106188 chr1:76137836 A/G cg22875332 chr1:76189707 ACADM -0.55 -6.28 -0.49 5.25e-9 Daytime sleep phenotypes; TGCT cis rs7226408 1.000 rs72883558 chr18:34372036 A/G cg06757138 chr18:34340585 FHOD3 0.28 4.76 0.39 5.23e-6 Obesity-related traits; TGCT cis rs6089584 0.927 rs2296083 chr20:60574216 C/T cg13770153 chr20:60521292 NA -0.53 -6.98 -0.53 1.58e-10 Body mass index; TGCT cis rs2228479 0.850 rs62056063 chr16:89903680 C/T cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs8028182 0.501 rs11072553 chr15:75932777 C/T cg20655648 chr15:75932815 IMP3 0.61 4.88 0.4 3.24e-6 Sudden cardiac arrest; TGCT cis rs12142240 0.698 rs17361763 chr1:46810670 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs7582180 0.629 rs10202326 chr2:100950237 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.95 -0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT cis rs9910055 0.659 rs3826412 chr17:42255097 A/G cg13607699 chr17:42295918 UBTF 0.58 5.35 0.43 4.02e-7 Total body bone mineral density; TGCT cis rs2549003 1.000 rs2070722 chr5:131824486 A/C cg21138405 chr5:131827807 IRF1 0.17 4.48 0.37 1.68e-5 Asthma (sex interaction); TGCT cis rs7772486 0.682 rs1337840 chr6:146042558 T/C cg23711669 chr6:146136114 FBXO30 -0.83 -8.95 -0.63 4.23e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs644799 1.000 rs586238 chr11:95560371 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.89 11.15 0.71 2.01e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1165205 0.558 rs531750 chr6:25882642 C/G cg03264133 chr6:25882463 NA -1.11 -14.8 -0.8 3.6e-29 Urate levels; TGCT trans rs7553035 1.000 rs2166104 chr1:211690818 A/T cg14538319 chr15:93464153 CHD2 0.6 7.31 0.55 2.85e-11 Retinopathy in non-diabetics; TGCT cis rs950027 0.620 rs1426932 chr15:45687256 T/C cg26924012 chr15:45694286 SPATA5L1 0.8 9.1 0.63 1.83e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs9788682 1.000 rs61204066 chr15:78815298 G/A cg06917634 chr15:78832804 PSMA4 -0.7 -5.17 -0.42 9.22e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg03264133 chr6:25882463 NA -0.62 -5.72 -0.46 7.56e-8 Intelligence (multi-trait analysis); TGCT cis rs523522 0.962 rs12814055 chr12:120987391 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg15659132 chr6:26577336 NA 0.87 10.79 0.7 1.52e-19 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.731 rs61770552 chr1:76373050 T/C cg03433033 chr1:76189801 ACADM 0.76 7.2 0.54 5.19e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7191439 0.674 rs4782429 chr16:88792097 A/G cg27087555 chr16:88793112 FAM38A -0.41 -5.36 -0.43 3.84e-7 Plateletcrit; TGCT cis rs17376456 0.877 rs13153245 chr5:93374891 G/A cg25358565 chr5:93447407 FAM172A 0.89 7.45 0.56 1.41e-11 Diabetic retinopathy; TGCT cis rs7829975 0.511 rs2976906 chr8:8342415 A/T cg15556689 chr8:8085844 FLJ10661 0.63 6.09 0.48 1.3e-8 Mood instability; TGCT cis rs9311474 0.967 rs610060 chr3:52273421 G/A cg10802521 chr3:52805072 NEK4 0.53 5.79 0.46 5.56e-8 Electroencephalogram traits; TGCT cis rs3096299 0.685 rs12446145 chr16:89542695 C/T cg08392591 chr16:89556376 ANKRD11 0.56 5.33 0.43 4.52e-7 Multiple myeloma (IgH translocation); TGCT cis rs10507380 0.824 rs79809567 chr13:27924952 T/C cg25543773 chr13:27185723 WASF3 0.32 4.52 0.38 1.45e-5 Electrocardiographic traits; TGCT cis rs727563 0.635 rs713988 chr22:42159072 A/G cg03806693 chr22:41940476 POLR3H 1.04 10.57 0.69 5.2e-19 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1972863 1.000 rs1972863 chr4:94579511 G/A cg20305610 chr4:95373302 PDLIM5 -0.52 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs7833790 0.660 rs1451995 chr8:82746123 G/C cg23324259 chr8:82754387 SNX16 0.61 4.71 0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs36051895 0.623 rs10975031 chr9:5253153 G/T cg02405213 chr9:5042618 JAK2 -0.73 -9.79 -0.66 4.1e-17 Pediatric autoimmune diseases; TGCT cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.04 13.09 0.76 3.91e-25 Prudent dietary pattern; TGCT cis rs210152 0.588 rs35817932 chr6:33457926 T/C cg16739976 chr6:34101401 GRM4 0.55 4.63 0.38 9.26e-6 Schizophrenia; TGCT cis rs11098499 0.954 rs10024844 chr4:120311528 A/G cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs172166 0.769 rs149965 chr6:28018689 T/A cg10876282 chr6:28092338 ZSCAN16 0.5 4.6 0.38 1.01e-5 Cardiac Troponin-T levels; TGCT cis rs12142240 0.698 rs1053627 chr1:46827728 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7264396 0.508 rs6060739 chr20:34567592 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.97 -0.41 2.21e-6 Total cholesterol levels; TGCT cis rs2153535 0.541 rs6938688 chr6:8521629 G/T cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs3741404 0.757 rs2282492 chr11:63918589 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.87 9.86 0.66 2.77e-17 Platelet count; TGCT cis rs1150668 0.796 rs9468372 chr6:28379361 T/A cg13525197 chr6:28411240 ZSCAN23 -0.52 -5.08 -0.42 1.33e-6 Pubertal anthropometrics; TGCT cis rs1008375 0.900 rs7658447 chr4:17579415 T/C cg18681998 chr4:17616180 MED28 0.83 7.51 0.56 1.02e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs868036 0.718 rs7170185 chr15:68117300 T/A cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs7192750 0.501 rs6499542 chr16:71859830 A/T cg06353428 chr16:71660113 MARVELD3 0.83 7.67 0.57 4.29e-12 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs4595586 0.870 rs1516558 chr12:39283119 A/G cg10518543 chr12:38710700 ALG10B -0.48 -4.73 -0.39 5.91e-6 Morning vs. evening chronotype; TGCT cis rs523522 0.962 rs11065154 chr12:120971417 T/C cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT trans rs916888 0.773 rs1378358 chr17:44787312 C/T cg22968622 chr17:43663579 NA 1.28 10.87 0.7 9.49e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs926938 0.563 rs360635 chr1:115420518 A/C cg12756093 chr1:115239321 AMPD1 0.41 6.44 0.5 2.37e-9 Autism; TGCT cis rs9393692 0.905 rs7747133 chr6:26293470 C/T cg13736514 chr6:26305472 NA -0.41 -5.77 -0.46 6.03e-8 Educational attainment; TGCT cis rs3947 0.951 rs1692814 chr8:11704298 T/C cg02840367 chr8:11660030 FDFT1 0.89 6.47 0.5 2e-9 Blood protein levels; TGCT cis rs2721195 1.000 rs6599530 chr8:145677418 C/G cg15857475 chr8:145742913 RECQL4;LRRC14 -0.82 -8.64 -0.61 2.39e-14 Age at first birth; TGCT cis rs10782582 0.564 rs17647711 chr1:76241710 C/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.51 4.59 0.38 1.06e-5 Daytime sleep phenotypes; TGCT cis rs7666738 0.830 rs13122456 chr4:98936011 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6840360 1.000 rs1105536 chr4:152605027 C/T cg17479576 chr4:152424074 FAM160A1 -0.47 -4.87 -0.4 3.28e-6 Intelligence (multi-trait analysis); TGCT cis rs765787 0.530 rs2433227 chr15:45517119 A/T cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs9467603 0.688 rs13191296 chr6:25684606 C/T cg16898833 chr6:26189333 HIST1H4D 1.36 6.05 0.48 1.56e-8 Intelligence (multi-trait analysis); TGCT cis rs7119038 0.818 rs10892279 chr11:118611781 G/A cg19308663 chr11:118741387 NA 0.22 4.57 0.38 1.17e-5 Sjögren's syndrome; TGCT cis rs55794721 0.509 rs7554255 chr1:25778106 C/T cg23205692 chr1:25664452 TMEM50A 0.48 5.07 0.41 1.42e-6 Plateletcrit;Mean corpuscular volume; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg00080972 chr5:178986291 RUFY1 0.56 6.86 0.52 2.95e-10 Lung cancer; TGCT cis rs3960554 0.569 rs1894761 chr7:75876754 C/T cg19105122 chr7:75896889 SRRM3 -0.54 -4.62 -0.38 9.59e-6 Eotaxin levels; TGCT cis rs9814567 0.964 rs1534028 chr3:134284639 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.18 -0.64 1.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7666738 0.830 rs13130923 chr4:99046281 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs453301 0.631 rs17700611 chr8:8793654 A/G cg15556689 chr8:8085844 FLJ10661 -0.61 -5.26 -0.43 6.1e-7 Joint mobility (Beighton score); TGCT cis rs10992471 0.603 rs7868013 chr9:95240173 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.79 -0.46 5.39e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6752107 1.000 rs13391356 chr2:234170369 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.61 0.38 9.73e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2046867 0.862 rs62251645 chr3:72805733 T/C cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4843747 0.671 rs72818577 chr16:88111181 G/A cg06915872 chr16:87998081 BANP -0.3 -4.58 -0.38 1.1e-5 Menopause (age at onset); TGCT cis rs8072100 0.817 rs11869940 chr17:45578435 T/A cg08085267 chr17:45401833 C17orf57 0.44 4.63 0.38 8.96e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7086627 0.515 rs11202960 chr10:82209807 G/A cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs7937840 0.581 rs4963461 chr11:61884044 G/A cg05871569 chr11:61891931 INCENP 0.7 6.44 0.5 2.38e-9 Breast cancer; TGCT trans rs7726839 0.794 rs10474792 chr5:600058 G/A cg25482853 chr8:67687455 SGK3 0.99 7.83 0.58 1.85e-12 Obesity-related traits; TGCT cis rs3784262 0.528 rs4238327 chr15:58336218 C/T cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.38 -0.5 3.14e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs6089829 0.962 rs6089824 chr20:61659207 A/G cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9398235 0.929 rs2073211 chr6:110729270 A/G cg19196401 chr6:110721138 DDO 0.47 4.48 0.37 1.67e-5 Systemic lupus erythematosus; TGCT cis rs2204008 0.658 rs11495742 chr12:38395688 C/A cg26384229 chr12:38710491 ALG10B 0.89 7.9 0.58 1.26e-12 Bladder cancer; TGCT cis rs7027203 0.595 rs7846827 chr9:96546525 C/T cg14598338 chr9:96623480 NA 0.5 7.2 0.54 5.11e-11 DNA methylation (variation); TGCT trans rs6740731 0.518 rs34586719 chr2:145295647 C/T cg03855592 chr7:113034122 NA 0.42 6.83 0.52 3.31e-10 Coronary artery disease; TGCT cis rs1555895 0.576 rs4881536 chr10:848058 A/G cg02193355 chr10:851439 NA 0.23 5.23 0.43 6.88e-7 Survival in rectal cancer; TGCT cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg09904177 chr6:26538194 HMGN4 0.68 6.27 0.49 5.41e-9 Intelligence (multi-trait analysis); TGCT cis rs709400 0.628 rs12879085 chr14:103874420 G/A cg26031613 chr14:104095156 KLC1 -0.83 -9.19 -0.64 1.17e-15 Body mass index; TGCT cis rs6671200 0.790 rs640527 chr1:95705615 G/A cg03123541 chr1:95699097 RWDD3 -0.91 -6.4 -0.5 2.93e-9 Stearic acid (18:0) levels; TGCT cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs12711979 0.509 rs10178286 chr2:3823821 A/G cg17052675 chr2:3827356 NA 0.53 12.1 0.74 9.98e-23 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs9291683 0.588 rs3756236 chr4:10013463 T/A cg00071950 chr4:10020882 SLC2A9 0.76 10.38 0.68 1.55e-18 Bone mineral density; TGCT cis rs7617773 0.780 rs6793223 chr3:48364101 C/T cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT trans rs208520 0.661 rs7766144 chr6:66827795 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.56 -0.69 5.53e-19 Exhaled nitric oxide output; TGCT cis rs624899 0.655 rs8109248 chr19:11641375 C/T cg12854483 chr19:11649671 CNN1 0.63 5.91 0.47 3.12e-8 Presence of antiphospholipid antibodies; TGCT cis rs7980687 0.527 rs1626703 chr12:123710835 A/C cg00376283 chr12:123451042 ABCB9 0.78 6.61 0.51 1.05e-9 Height;Educational attainment;Head circumference (infant); TGCT cis rs6088590 0.610 rs6120663 chr20:33081906 A/C cg06115741 chr20:33292138 TP53INP2 -0.64 -5.68 -0.45 8.9e-8 Coronary artery disease; TGCT cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg06601766 chr17:61851465 DDX42;CCDC47 -0.55 -4.83 -0.4 4.02e-6 Height; TGCT cis rs9926296 0.712 rs258330 chr16:89729574 T/G cg21285383 chr16:89894308 SPIRE2 -0.32 -4.52 -0.38 1.42e-5 Vitiligo; TGCT cis rs586688 0.625 rs609396 chr1:201655233 C/T cg07139329 chr1:201708558 NAV1 -0.52 -5.32 -0.43 4.74e-7 Obesity-related traits; TGCT cis rs9486719 0.843 rs2472876 chr6:96845723 A/G cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs7582180 0.764 rs10460478 chr2:100919735 G/A cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.45e-6 Intelligence (multi-trait analysis); TGCT cis rs2070488 0.965 rs13093640 chr3:38487176 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs7647973 0.626 rs1996664 chr3:49878395 A/G cg05785598 chr3:49045655 WDR6 -0.42 -5.32 -0.43 4.71e-7 Menarche (age at onset); TGCT cis rs1046896 0.594 rs9914570 chr17:80783721 C/T cg03160526 chr17:80928410 B3GNTL1 0.34 4.73 0.39 5.95e-6 Glycated hemoglobin levels; TGCT cis rs10089 1.000 rs10060181 chr5:127475573 A/G cg19767477 chr5:127420684 SLC12A2 -0.43 -4.56 -0.38 1.21e-5 Ileal carcinoids; TGCT cis rs7919533 0.564 rs9415041 chr10:73524184 G/A cg00101602 chr10:73857843 ASCC1 0.29 4.56 0.38 1.22e-5 Monocyte count; TGCT cis rs7843479 0.965 rs11135742 chr8:21802910 A/T cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs425277 0.628 rs3128340 chr1:2047496 C/G cg03732007 chr1:2071316 PRKCZ -0.28 -6.09 -0.48 1.28e-8 Height; TGCT cis rs4319547 0.656 rs7975747 chr12:122816995 C/T cg08088222 chr12:122070432 ORAI1 0.27 4.74 0.39 5.83e-6 Body mass index; TGCT cis rs28595532 0.920 rs115084148 chr4:119739290 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs877529 0.934 rs139418 chr22:39557162 A/C cg18708252 chr22:39545030 CBX7 -0.35 -4.74 -0.39 5.7e-6 Multiple myeloma; TGCT cis rs11785400 1.000 rs4518642 chr8:143737396 T/C cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs6912958 0.935 rs2179844 chr6:88165773 C/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.74 -0.39 5.79e-6 Monocyte percentage of white cells; TGCT cis rs6540559 1.000 rs4844895 chr1:209958580 T/C cg23283495 chr1:209979779 IRF6 0.67 5.65 0.45 1.03e-7 Cleft lip with or without cleft palate; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg18538332 chr22:24372958 LOC391322 0.86 7.4 0.55 1.79e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7666738 0.546 rs34621463 chr4:98793357 G/C cg05340658 chr4:99064831 C4orf37 0.51 5.65 0.45 1.03e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 0.761 rs1830084 chr3:133508464 A/T cg16414030 chr3:133502952 NA 0.67 11.56 0.72 2.02e-21 Iron status biomarkers; TGCT cis rs12142240 0.698 rs56130131 chr1:46861306 A/C cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs12548874 0.607 rs12543492 chr8:95891843 C/A cg16049864 chr8:95962084 TP53INP1 -0.58 -6.87 -0.53 2.74e-10 Hemoglobin concentration; TGCT cis rs1008375 0.863 rs2058336 chr4:17608299 T/C cg18681998 chr4:17616180 MED28 0.98 10.43 0.68 1.17e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7119 0.717 rs11634174 chr15:77811232 A/T cg27398640 chr15:77910606 LINGO1 -0.25 -4.55 -0.38 1.26e-5 Type 2 diabetes; TGCT cis rs7666738 0.830 rs2903150 chr4:99027184 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4720575 0.931 rs10242850 chr7:47099868 A/C cg00036614 chr7:47093842 NA -0.21 -5.28 -0.43 5.69e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs4665809 1.000 rs11126375 chr2:26344787 G/A cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs2816958 0.708 rs2821329 chr1:200082360 T/C cg07971716 chr1:199773294 NA 0.47 4.6 0.38 1.02e-5 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs11690935 0.959 rs10204501 chr2:172588865 C/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.51 -0.75 9.78e-24 Schizophrenia; TGCT cis rs4568518 0.501 rs6966247 chr7:17989247 A/G cg03009463 chr7:17980271 SNX13 0.57 4.57 0.38 1.18e-5 Measles; TGCT cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.18e-7 Developmental language disorder (linguistic errors); TGCT cis rs1023500 0.552 rs133368 chr22:42463689 T/C cg05082376 chr22:42548792 NA -0.23 -5.44 -0.44 2.72e-7 Schizophrenia; TGCT cis rs116095464 0.510 rs10057501 chr5:239545 T/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg16423285 chr20:60520624 NA -0.77 -9.89 -0.66 2.34e-17 Obesity-related traits; TGCT trans rs561341 1.000 rs117979353 chr17:30272866 A/G cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 5.23 0.43 6.93e-7 Height; TGCT cis rs4654899 1.000 rs6426668 chr1:21396596 T/C cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs35146811 0.660 rs3779046 chr7:99779243 A/G cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs9611565 0.729 rs4822027 chr22:41786227 G/A cg06634786 chr22:41940651 POLR3H -0.89 -8.45 -0.6 6.78e-14 Vitiligo; TGCT cis rs1403694 0.695 rs11919484 chr3:186432839 G/T cg12454167 chr3:186435060 KNG1 0.5 8.56 0.61 3.65e-14 Blood protein levels; TGCT cis rs13256369 0.756 rs13280759 chr8:8562995 G/T cg17143192 chr8:8559678 CLDN23 0.56 5.31 0.43 4.9e-7 Obesity-related traits; TGCT cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs910316 0.763 rs175036 chr14:75464295 C/T cg11812906 chr14:75593930 NEK9 -0.59 -5.69 -0.45 8.84e-8 Height; TGCT cis rs875971 0.522 rs4718286 chr7:65292764 A/G cg18876405 chr7:65276391 NA 0.35 5.66 0.45 1.01e-7 Aortic root size; TGCT cis rs2302045 1.000 rs2270044 chr2:242056924 A/G cg20856893 chr2:242997758 NA -0.56 -4.66 -0.39 8.02e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs7267979 0.903 rs6115109 chr20:25239667 G/A cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6882046 0.513 rs647983 chr5:88048071 T/C cg22951263 chr5:87985283 NA -0.55 -5.88 -0.47 3.54e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg14983838 chr19:29218262 NA 0.83 6.81 0.52 3.8e-10 Methadone dose in opioid dependence; TGCT cis rs17473412 0.609 rs78154385 chr5:122858945 A/G cg15125798 chr5:122621645 NA -0.54 -4.94 -0.41 2.5e-6 Total body bone mineral density; TGCT cis rs67311347 1.000 rs73078123 chr3:40458963 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs28595532 0.920 rs115090643 chr4:119729825 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs7916697 0.947 rs9783176 chr10:70002393 A/T cg18338521 chr10:69995036 NA -0.28 -4.47 -0.37 1.75e-5 Optic disc area; TGCT cis rs2303745 0.589 rs6512182 chr19:17399476 G/T cg02221750 chr19:17393354 ANKLE1 -0.46 -5.87 -0.47 3.73e-8 Systemic lupus erythematosus; TGCT trans rs1814175 0.645 rs10839382 chr11:49823172 C/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs7666738 0.791 rs13127542 chr4:98949159 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2760061 0.819 rs708114 chr1:228197496 G/A cg02753203 chr1:228287806 NA 0.31 5.94 0.47 2.62e-8 Diastolic blood pressure; TGCT cis rs9682041 1.000 rs57508070 chr3:170074374 C/A cg11886554 chr3:170076028 SKIL 0.84 6.34 0.49 3.84e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7412746 0.611 rs11204748 chr1:150927369 G/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs2806561 0.765 rs2806557 chr1:23503372 T/A cg12483005 chr1:23474871 LUZP1 0.37 4.84 0.4 3.74e-6 Height; TGCT cis rs6088580 0.668 rs1205340 chr20:32923871 G/A cg08999081 chr20:33150536 PIGU -0.24 -4.74 -0.39 5.68e-6 Glomerular filtration rate (creatinine); TGCT cis rs3617 0.625 rs2240915 chr3:52859526 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.48 4.59 0.38 1.08e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1005277 0.528 rs2057228 chr10:38515766 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT trans rs941408 0.928 rs2260414 chr19:2796316 G/A cg22153745 chr1:153894579 GATAD2B -0.63 -6.84 -0.52 3.15e-10 Total cholesterol levels; TGCT cis rs2549003 1.000 rs2549003 chr5:131829297 A/G cg21138405 chr5:131827807 IRF1 0.18 4.72 0.39 6.31e-6 Asthma (sex interaction); TGCT cis rs13191362 0.935 rs35537826 chr6:163145867 G/A cg21926612 chr6:163149169 PACRG;PARK2 1.13 8.92 0.63 5.03e-15 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9549367 0.789 rs9549715 chr13:113908240 G/C cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs2729354 0.903 rs1846568 chr11:57357714 A/C cg24343310 chr11:57249947 NA 0.29 5.16 0.42 9.56e-7 Blood protein levels; TGCT cis rs6088590 0.561 rs6059926 chr20:33164804 C/T cg08999081 chr20:33150536 PIGU 0.25 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg03264133 chr6:25882463 NA -0.64 -5.85 -0.47 4.08e-8 Intelligence (multi-trait analysis); TGCT cis rs7586879 0.687 rs11892869 chr2:25096692 A/T cg15423357 chr2:25149977 NA 0.46 4.47 0.37 1.72e-5 Body mass index; TGCT cis rs858239 0.570 rs10242166 chr7:23162799 A/G cg05602783 chr7:23145260 KLHL7 -0.65 -5.52 -0.44 1.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs523522 0.571 rs11065120 chr12:120875456 C/T cg12219531 chr12:120966889 COQ5 0.7 4.76 0.39 5.23e-6 High light scatter reticulocyte count; TGCT cis rs10936602 0.527 rs1920119 chr3:169540397 T/C cg08193579 chr3:169529701 LRRC34 0.28 5.16 0.42 9.55e-7 Renal cell carcinoma; TGCT cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.69e-9 Blood metabolite levels; TGCT cis rs7674212 0.507 rs223322 chr4:103800194 G/A cg16532752 chr4:104119610 CENPE -0.62 -5.59 -0.45 1.41e-7 Type 2 diabetes; TGCT cis rs66887589 0.616 rs6843509 chr4:120220196 G/A cg24670566 chr4:120433619 PDE5A 0.21 4.57 0.38 1.17e-5 Diastolic blood pressure; TGCT cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg03303774 chr4:1407052 NA 0.29 4.71 0.39 6.55e-6 Obesity-related traits; TGCT cis rs2204008 0.575 rs10444564 chr12:38043782 T/C cg13010199 chr12:38710504 ALG10B 0.65 5.23 0.42 7.11e-7 Bladder cancer; TGCT cis rs916888 0.821 rs199506 chr17:44859031 A/G cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1005277 0.579 rs2103938 chr10:38493998 T/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.22 -0.59 2.35e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7044106 0.791 rs10985009 chr9:123493039 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.51 -5.64 -0.45 1.09e-7 Hip circumference adjusted for BMI; TGCT cis rs881375 0.933 rs7859805 chr9:123664123 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.06 0.41 1.49e-6 Rheumatoid arthritis; TGCT cis rs17221829 0.965 rs10830370 chr11:89461535 G/T cg02982614 chr11:89391479 FOLH1B -0.3 -5.29 -0.43 5.47e-7 Anxiety in major depressive disorder; TGCT cis rs7246657 0.943 rs10404602 chr19:37825633 A/T cg18154014 chr19:37997991 ZNF793 0.98 6.49 0.5 1.87e-9 Coronary artery calcification; TGCT cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -8.51 -0.61 4.86e-14 Platelet count; TGCT cis rs806215 1.000 rs698406 chr7:127255285 C/G cg25922125 chr7:127225783 GCC1 0.58 5.86 0.47 3.92e-8 Type 2 diabetes; TGCT cis rs4819052 0.851 rs13049337 chr21:46663460 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4727027 0.933 rs12704063 chr7:148827909 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Vitiligo; TGCT cis rs10782582 0.593 rs11589276 chr1:76105545 G/A cg22875332 chr1:76189707 ACADM -0.52 -6.26 -0.49 5.72e-9 Daytime sleep phenotypes; TGCT cis rs9914988 1.000 rs9914988 chr17:27183104 G/A cg20469991 chr17:27169893 C17orf63 0.69 5.05 0.41 1.51e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9926296 0.632 rs7206546 chr16:89799079 C/T cg03388025 chr16:89894329 SPIRE2 -0.32 -4.74 -0.39 5.8e-6 Vitiligo; TGCT cis rs1865760 0.865 rs9393678 chr6:25945819 C/T cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs28595532 0.920 rs116091383 chr4:119635518 A/G cg14228332 chr4:119757509 SEC24D 1.02 5.37 0.43 3.75e-7 Cannabis dependence symptom count; TGCT cis rs1008375 1.000 rs3815414 chr4:17606659 A/G cg16339924 chr4:17578868 LAP3 -0.63 -5.31 -0.43 4.86e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2070488 0.662 rs7652475 chr3:38481341 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.72 5.94 0.47 2.7e-8 Electrocardiographic conduction measures; TGCT cis rs908922 0.676 rs4845780 chr1:152488846 T/G cg20991723 chr1:152506922 NA 0.47 6.71 0.52 6.16e-10 Hair morphology; TGCT cis rs7917772 0.536 rs17783771 chr10:104410736 C/T cg05855489 chr10:104503620 C10orf26 -0.59 -4.91 -0.4 2.76e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6582630 0.519 rs12372510 chr12:38293074 T/C cg26384229 chr12:38710491 ALG10B 0.78 6.91 0.53 2.24e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs7542091 0.704 rs12022221 chr1:210046178 A/C cg22029157 chr1:209979665 IRF6 0.59 5.76 0.46 6.28e-8 Monobrow; TGCT cis rs9611565 0.592 rs5996038 chr22:41965300 T/C cg06481639 chr22:41940642 POLR3H -0.67 -5.71 -0.46 7.87e-8 Vitiligo; TGCT trans rs16860537 1.000 rs74713356 chr1:183236667 T/C cg10317387 chr2:88470873 THNSL2 -0.67 -6.62 -0.51 9.68e-10 Systemic lupus erythematosus and Systemic sclerosis; TGCT trans rs6089829 0.888 rs4809465 chr20:61671156 G/C cg13615516 chr5:77269221 NA 0.73 8.39 0.6 9.12e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs6558530 0.640 rs4875889 chr8:1695291 C/G cg09410841 chr8:1729607 CLN8 0.67 5.88 0.47 3.61e-8 Systolic blood pressure; TGCT cis rs8062405 0.679 rs72793818 chr16:28893137 G/A cg09754948 chr16:28834200 ATXN2L 0.6 4.48 0.37 1.65e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2032447 0.520 rs198818 chr6:26125711 A/C cg03517284 chr6:25882590 NA 0.5 4.56 0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs4927850 1.000 rs7627706 chr3:195753353 A/C cg02975922 chr3:195473998 MUC4 -0.24 -5.47 -0.44 2.4e-7 Pancreatic cancer; TGCT cis rs11105298 0.891 rs10858865 chr12:89846476 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1062746 0.771 rs10514621 chr16:87369578 G/T cg02258303 chr16:87377426 FBXO31 -0.17 -4.47 -0.37 1.72e-5 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs838147 0.537 rs504963 chr19:49208865 G/A cg04599840 chr19:48886497 KDELR1 0.22 4.49 0.37 1.61e-5 Dietary macronutrient intake; TGCT cis rs2073300 1.000 rs6048826 chr20:23458050 C/A cg09953122 chr20:23471693 CST8 -0.59 -4.75 -0.39 5.62e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs1519814 0.659 rs7829279 chr8:121023514 A/G cg22335954 chr8:121166405 COL14A1 -0.37 -4.73 -0.39 6.06e-6 Breast cancer; TGCT cis rs4819052 0.724 rs1304487 chr21:46657283 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.71 -6.3 -0.49 4.82e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs3780486 0.846 rs10971438 chr9:33180308 A/G cg04842962 chr6:43655489 MRPS18A 1.12 12.0 0.73 1.71e-22 IgG glycosylation; TGCT cis rs7829975 0.711 rs1039916 chr8:8685854 A/G cg08975724 chr8:8085496 FLJ10661 0.59 5.27 0.43 5.74e-7 Mood instability; TGCT cis rs9858542 0.953 rs11713474 chr3:49611457 A/G cg03060546 chr3:49711283 APEH -0.63 -5.48 -0.44 2.28e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs9473924 0.542 rs2744504 chr6:50798668 G/C cg14470998 chr6:50812995 TFAP2B 1.33 7.94 0.58 1.03e-12 Body mass index; TGCT cis rs2153535 0.580 rs9406165 chr6:8488837 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.05 0.41 1.51e-6 Motion sickness; TGCT cis rs9549367 0.713 rs9549681 chr13:113829873 T/C cg00898013 chr13:113819073 PROZ -0.55 -7.05 -0.53 1.12e-10 Platelet distribution width; TGCT cis rs1723838 0.510 rs45523540 chr11:73692990 G/A cg26954736 chr11:73693896 UCP2 -1.41 -6.38 -0.5 3.22e-9 Obesity-related traits; TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg22166914 chr1:53195759 ZYG11B 0.33 5.38 0.43 3.6e-7 Monocyte count; TGCT cis rs950169 0.650 rs12902052 chr15:85125838 A/T cg17173187 chr15:85201210 NMB 0.47 4.87 0.4 3.39e-6 Schizophrenia; TGCT cis rs10791097 0.694 rs4370948 chr11:130755700 A/C cg05962950 chr11:130786565 SNX19 0.91 11.71 0.72 8.72e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2120019 1.000 rs12910644 chr15:75358388 A/G cg09165964 chr15:75287851 SCAMP5 -1.18 -9.83 -0.66 3.33e-17 Blood trace element (Zn levels); TGCT cis rs6754311 0.551 rs2304599 chr2:136528004 C/G cg07169764 chr2:136633963 MCM6 -0.71 -6.47 -0.5 2.09e-9 Mosquito bite size; TGCT cis rs1048238 0.506 rs1262788 chr1:16215608 G/C cg22431228 chr1:16359049 CLCNKA 0.24 4.74 0.39 5.8e-6 Systolic blood pressure; TGCT cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg06481639 chr22:41940642 POLR3H -0.72 -6.52 -0.51 1.61e-9 Vitiligo; TGCT cis rs7666738 0.606 rs10006454 chr4:99080361 G/A cg05340658 chr4:99064831 C4orf37 0.44 4.8 0.4 4.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7208859 0.623 rs11651857 chr17:28926362 G/T cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6920965 0.509 rs575811 chr6:126162282 T/C cg05901451 chr6:126070800 HEY2 0.56 5.0 0.41 1.94e-6 High light scatter reticulocyte count; TGCT cis rs2836974 0.897 rs13047678 chr21:40708853 C/T cg06238570 chr21:40685208 BRWD1 0.63 5.29 0.43 5.45e-7 Cognitive function; TGCT cis rs67311347 1.000 rs951560 chr3:40463471 A/G cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs9926296 0.508 rs1558184 chr16:89842374 T/G cg03388025 chr16:89894329 SPIRE2 0.51 8.89 0.62 5.97e-15 Vitiligo; TGCT cis rs3748682 0.861 rs28625842 chr1:38310786 G/A cg04496824 chr1:38276835 MTF1 0.21 4.61 0.38 1.01e-5 Hypothyroidism; TGCT cis rs7267979 1.000 rs6107047 chr20:25442097 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11122272 0.735 rs2739510 chr1:231526718 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.3 -0.49 4.72e-9 Hemoglobin concentration; TGCT cis rs28785552 0.800 rs10853854 chr19:53232128 A/G cg10871876 chr19:53194124 ZNF83 -0.46 -6.26 -0.49 5.63e-9 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs6547741 1.000 rs6547741 chr2:27855924 G/A cg27432699 chr2:27873401 GPN1 0.18 4.63 0.38 9.05e-6 Oral cavity cancer; TGCT trans rs7819412 0.654 rs6987059 chr8:11071057 A/G cg15556689 chr8:8085844 FLJ10661 -0.75 -6.72 -0.52 5.82e-10 Triglycerides; TGCT cis rs2404602 0.740 rs34924128 chr15:76965169 T/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs72781680 0.898 rs72796152 chr2:23933626 G/A cg08917208 chr2:24149416 ATAD2B 0.76 4.6 0.38 1.03e-5 Lymphocyte counts; TGCT cis rs13242816 1.000 rs35505552 chr7:116104867 T/A cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT trans rs916888 0.610 rs199454 chr17:44800110 G/A cg22968622 chr17:43663579 NA -0.99 -9.5 -0.65 2.03e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs270601 0.739 rs1979981 chr5:131601720 G/A cg24060327 chr5:131705240 SLC22A5 -0.66 -6.85 -0.52 3.07e-10 Acylcarnitine levels; TGCT cis rs4499344 0.577 rs259289 chr19:33164927 G/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.87 9.38 0.64 3.95e-16 Mean platelet volume; TGCT cis rs9638182 0.725 rs111837003 chr7:72907459 C/T cg14087351 chr7:73037990 MLXIPL -0.57 -4.52 -0.38 1.4e-5 Triglycerides; TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg27535305 chr1:53392650 SCP2 -0.25 -4.77 -0.39 5.07e-6 Monocyte count; TGCT cis rs7647973 0.626 rs4855845 chr3:49687043 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.76 0.39 5.27e-6 Menarche (age at onset); TGCT cis rs12908161 1.000 rs12912388 chr15:85344550 T/A cg17173187 chr15:85201210 NMB 0.57 6.39 0.5 3.07e-9 Schizophrenia; TGCT cis rs651907 0.640 rs771573 chr3:101620896 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.64 6.49 0.5 1.88e-9 Colorectal cancer; TGCT cis rs597539 0.652 rs627731 chr11:68698663 A/C cg21862992 chr11:68658383 NA 0.44 6.07 0.48 1.42e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2760061 0.784 rs1745414 chr1:228212159 T/A cg18477163 chr1:228402036 OBSCN 0.35 7.47 0.56 1.22e-11 Diastolic blood pressure; TGCT cis rs11098499 0.865 rs10032158 chr4:120391632 C/T cg09307838 chr4:120376055 NA 0.69 6.56 0.51 1.31e-9 Corneal astigmatism; TGCT cis rs769267 0.895 rs1858999 chr19:19497669 C/G cg03709012 chr19:19516395 GATAD2A -0.76 -6.48 -0.5 1.93e-9 Tonsillectomy; TGCT cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.609 rs6060983 chr20:30420924 T/C cg13852791 chr20:30311386 BCL2L1 0.84 7.49 0.56 1.1e-11 Mean corpuscular hemoglobin; TGCT cis rs231513 0.906 rs11653808 chr17:42005366 A/T cg26893861 chr17:41843967 DUSP3 0.73 5.1 0.42 1.25e-6 Cognitive function; TGCT cis rs3829109 0.564 rs4307444 chr9:139279634 C/T cg13741927 chr9:139327495 INPP5E -0.23 -4.83 -0.4 4.03e-6 Peak insulin response;Acute insulin response; TGCT cis rs1215050 0.791 rs165252 chr4:98758728 A/C cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3027009 0.881 rs12045546 chr1:159132532 A/G cg11719576 chr1:158153771 CD1D 0.37 4.62 0.38 9.55e-6 Lean body mass and age at menarche (combined); TGCT cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.49 -0.61 5.27e-14 Platelet count; TGCT cis rs59107033 0.607 rs73188507 chr3:123126674 T/C cg04890266 chr3:123102914 ADCY5 -0.38 -5.29 -0.43 5.31e-7 Lymphocyte counts; TGCT trans rs941408 1.000 rs941410 chr19:2787329 G/A cg19676328 chr12:49525230 TUBA1B -0.69 -6.66 -0.51 7.89e-10 Total cholesterol levels; TGCT cis rs9858542 0.953 rs12330269 chr3:49513910 G/A cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs28493229 0.708 rs10407889 chr19:41161078 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs644799 0.710 rs473852 chr11:95568757 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.77 7.46 0.56 1.28e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2299587 0.519 rs3850746 chr8:17787536 C/T cg01800426 chr8:17659068 MTUS1 0.64 5.52 0.44 1.91e-7 Economic and political preferences; TGCT cis rs1538970 0.924 rs12046816 chr1:45891543 G/T cg05343316 chr1:45956843 TESK2 0.78 6.29 0.49 4.97e-9 Platelet count; TGCT cis rs10504229 0.639 rs66667899 chr8:58117065 C/T cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs74233809 0.591 rs284853 chr10:104574642 T/A cg05855489 chr10:104503620 C10orf26 -0.73 -4.99 -0.41 1.96e-6 Birth weight; TGCT cis rs4476553 0.868 rs2280041 chr4:4709657 G/A cg05554346 chr4:4145468 NA 0.4 4.73 0.39 5.9e-6 Response to amphetamines; TGCT cis rs2204008 0.665 rs11495668 chr12:38221018 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.43 0.56 1.51e-11 Bladder cancer; TGCT cis rs7103648 0.618 rs11039284 chr11:47564785 A/G cg20307385 chr11:47447363 PSMC3 0.9 8.49 0.61 5.41e-14 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs877282 0.898 rs11253356 chr10:768604 G/A cg17470449 chr10:769945 NA 0.28 4.44 0.37 1.97e-5 Uric acid levels; TGCT cis rs3733585 0.624 rs76574510 chr4:9953252 T/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.609 rs28833816 chr4:98868866 T/C cg17366294 chr4:99064904 C4orf37 0.65 5.93 0.47 2.83e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs73001065 0.711 rs58489806 chr19:19456917 C/T cg03709012 chr19:19516395 GATAD2A 0.92 4.62 0.38 9.41e-6 LDL cholesterol; TGCT cis rs2549003 1.000 rs2548999 chr5:131831058 G/T cg21138405 chr5:131827807 IRF1 -0.18 -4.52 -0.38 1.44e-5 Asthma (sex interaction); TGCT cis rs11864453 0.713 rs9926156 chr16:72142895 G/C cg14768367 chr16:72042858 DHODH 0.51 4.91 0.4 2.77e-6 Fibrinogen levels; TGCT cis rs7833790 0.632 rs6415653 chr8:82702536 A/G cg06027949 chr8:82754900 SNX16 -0.67 -5.02 -0.41 1.77e-6 Diastolic blood pressure; TGCT cis rs506338 0.517 rs17146216 chr11:64451281 C/G cg19395706 chr11:64412079 NRXN2 0.53 6.26 0.49 5.62e-9 Body mass index;Urate levels; TGCT cis rs4820539 0.966 rs2267000 chr22:23455366 A/G cg14186256 chr22:23484241 RTDR1 0.92 10.9 0.7 8.32e-20 Bone mineral density; TGCT cis rs2243480 1.000 rs410128 chr7:65603173 C/T cg18252515 chr7:66147081 NA -1.14 -7.01 -0.53 1.37e-10 Diabetic kidney disease; TGCT cis rs67311347 1.000 rs11715214 chr3:40403004 C/A cg17264618 chr3:40429014 ENTPD3 0.31 4.59 0.38 1.09e-5 Renal cell carcinoma; TGCT trans rs877282 0.891 rs11253406 chr10:796297 G/A cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs12643440 0.538 rs4280726 chr4:17139547 T/C cg22650099 chr4:17144496 NA -0.44 -4.45 -0.37 1.86e-5 Metabolite levels (Pyroglutamine); TGCT cis rs5167 0.743 rs8111069 chr19:45483438 A/C cg09555818 chr19:45449301 APOC2 0.23 5.02 0.41 1.78e-6 Blood protein levels; TGCT cis rs10883723 0.810 rs3818470 chr10:104263675 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7607369 0.580 rs7594289 chr2:219652286 A/G cg02176678 chr2:219576539 TTLL4 -0.45 -5.86 -0.47 3.89e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs28595532 0.920 rs115084148 chr4:119739290 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2742417 1.000 rs2742435 chr3:45740863 C/T cg04837898 chr3:45731254 SACM1L -0.51 -5.41 -0.44 3.08e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6546537 0.550 rs7568057 chr2:69877783 T/G cg10773587 chr2:69614142 GFPT1 -0.51 -4.49 -0.37 1.6e-5 Serum thyroid-stimulating hormone levels; TGCT cis rs4665809 1.000 rs4665306 chr2:26319124 C/T cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs80282103 0.618 rs74117831 chr10:1145707 A/C cg18964960 chr10:1102726 WDR37 0.98 4.57 0.38 1.15e-5 Glomerular filtration rate (creatinine); TGCT cis rs208520 0.690 rs207119 chr6:66786408 C/T cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs875971 0.520 rs2420597 chr7:65915986 A/G cg11764359 chr7:65958608 NA 0.58 5.33 0.43 4.47e-7 Aortic root size; TGCT cis rs6032067 0.561 rs6032104 chr20:43932412 G/A cg16667508 chr20:43936853 MATN4;RBPJL -0.48 -7.03 -0.53 1.2e-10 Blood protein levels; TGCT cis rs858239 0.720 rs10227559 chr7:23272144 G/A cg05602783 chr7:23145260 KLHL7 -0.69 -5.38 -0.43 3.59e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs7786808 0.644 rs4909081 chr7:158200785 G/A cg01191920 chr7:158217561 PTPRN2 -0.42 -6.33 -0.49 4.13e-9 Obesity-related traits; TGCT cis rs28785552 0.769 rs7253672 chr19:53243212 G/C cg10871876 chr19:53194124 ZNF83 0.54 7.66 0.57 4.61e-12 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs17253792 0.822 rs75991559 chr14:56092419 A/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7659604 0.540 rs13113421 chr4:122670064 G/A cg19748678 chr4:122722346 EXOSC9 -0.5 -4.83 -0.4 3.93e-6 Type 2 diabetes; TGCT cis rs7255045 0.664 rs4614850 chr19:12974636 G/T cg06537894 chr19:12978706 MAST1 -0.49 -4.48 -0.37 1.69e-5 Mean corpuscular volume; TGCT cis rs7264396 0.790 rs6060516 chr20:34214368 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.67 -0.39 7.62e-6 Total cholesterol levels; TGCT cis rs9611565 0.681 rs6002372 chr22:41801299 A/T cg17554472 chr22:41940697 POLR3H 0.43 4.6 0.38 1.01e-5 Vitiligo; TGCT cis rs17376456 0.877 rs7701011 chr5:93311456 G/A cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs11785400 0.642 rs4256574 chr8:143725705 C/T cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs806215 1.000 rs806214 chr7:127237003 C/T cg25922125 chr7:127225783 GCC1 -0.56 -6.11 -0.48 1.16e-8 Type 2 diabetes; TGCT cis rs2153535 0.580 rs1414346 chr6:8471574 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs11651000 0.625 rs2074190 chr17:45811210 A/G cg06532163 chr17:45867833 NA 0.33 5.27 0.43 5.75e-7 IgG glycosylation; TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs9549367 0.673 rs3751413 chr13:113854715 C/T cg18105134 chr13:113819100 PROZ 0.43 7.77 0.57 2.58e-12 Platelet distribution width; TGCT cis rs13108904 0.870 rs4974545 chr4:1271923 C/T cg05665937 chr4:1216051 CTBP1 0.24 4.64 0.38 8.83e-6 Obesity-related traits; TGCT cis rs1205863 1.000 rs1205865 chr6:11943612 A/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs57590327 0.508 rs4605572 chr3:81965751 A/G cg07356753 chr3:81810745 GBE1 -0.67 -5.89 -0.47 3.42e-8 Extraversion; TGCT cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.62 -0.51 9.69e-10 Alzheimer's disease; TGCT cis rs2303745 0.589 rs8103523 chr19:17398269 A/G cg02221750 chr19:17393354 ANKLE1 -0.46 -5.87 -0.47 3.7e-8 Systemic lupus erythematosus; TGCT cis rs9467773 0.511 rs11755443 chr6:26891603 T/C cg05738196 chr6:26577821 NA 0.68 6.47 0.5 2.02e-9 Intelligence (multi-trait analysis); TGCT cis rs875971 0.638 rs10278816 chr7:66036987 T/C cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg17554472 chr22:41940697 POLR3H -0.49 -5.22 -0.42 7.33e-7 Vitiligo; TGCT cis rs2066819 1.000 rs74673257 chr12:56638077 T/C cg26714650 chr12:56694279 CS -1.32 -6.2 -0.49 7.69e-9 Psoriasis vulgaris; TGCT cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg17971929 chr21:40555470 PSMG1 -0.51 -4.55 -0.38 1.24e-5 Menarche (age at onset); TGCT cis rs10791323 0.569 rs10791328 chr11:133713730 A/G cg03690763 chr11:133734501 NA -0.32 -5.07 -0.41 1.4e-6 Childhood ear infection; TGCT cis rs12701220 0.817 rs1058727 chr7:1087095 A/G cg27454412 chr7:1067447 C7orf50 -0.47 -4.54 -0.38 1.34e-5 Bronchopulmonary dysplasia; TGCT trans rs1005277 0.579 rs2505198 chr10:38393183 A/C cg27523141 chr10:43048294 ZNF37B 0.71 8.26 0.6 1.86e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2072499 0.833 rs2251847 chr1:156204047 G/A cg25208724 chr1:156163844 SLC25A44 0.98 10.36 0.68 1.7e-18 Testicular germ cell tumor; TGCT cis rs1949733 0.958 rs3103069 chr4:8509451 T/G cg13073564 chr4:8508604 NA 0.45 4.72 0.39 6.21e-6 Response to antineoplastic agents; TGCT cis rs854765 0.686 rs8065497 chr17:17782649 A/G cg09796270 chr17:17721594 SREBF1 -0.27 -5.45 -0.44 2.66e-7 Total body bone mineral density; TGCT cis rs739496 0.615 rs688920 chr12:112157262 C/T cg10833066 chr12:111807467 FAM109A 0.35 5.18 0.42 8.83e-7 Platelet count; TGCT cis rs79149102 0.579 rs7342601 chr15:75306795 G/T cg09165964 chr15:75287851 SCAMP5 1.04 5.73 0.46 7.2e-8 Lung cancer; TGCT cis rs9913156 0.517 rs7215300 chr17:4608622 T/C cg19197139 chr17:4613644 ARRB2 -0.61 -5.82 -0.46 4.82e-8 Lymphocyte counts; TGCT cis rs3733585 0.699 rs7676733 chr4:9966956 G/A cg00071950 chr4:10020882 SLC2A9 -0.57 -6.85 -0.52 3.12e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4843747 0.605 rs4072779 chr16:88107290 C/T cg06915872 chr16:87998081 BANP -0.29 -4.46 -0.37 1.8e-5 Menopause (age at onset); TGCT cis rs1878931 0.597 rs37814 chr16:3455247 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.71 -5.53 -0.44 1.83e-7 Body mass index (adult); TGCT cis rs10782582 0.609 rs6656501 chr1:76266126 A/C cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs1215050 1.000 rs1215050 chr4:98849826 A/G cg05340658 chr4:99064831 C4orf37 -0.48 -5.7 -0.46 8.27e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1371867 0.875 rs2439456 chr8:101336874 C/T cg06002616 chr8:101225028 SPAG1 -0.54 -6.36 -0.5 3.57e-9 Atrioventricular conduction; TGCT cis rs10876993 0.893 rs7979246 chr12:58092554 A/G cg15848620 chr12:58087721 OS9 -0.71 -5.79 -0.46 5.49e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs67073037 0.955 rs4666132 chr2:29136489 G/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs17601876 0.814 rs11636639 chr15:51563092 T/G cg19946085 chr15:51559439 CYP19A1 -0.33 -5.07 -0.41 1.42e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs10186029 0.708 rs4672673 chr2:213981463 A/G cg08319019 chr2:214017104 IKZF2 0.65 5.97 0.47 2.35e-8 Systemic sclerosis; TGCT cis rs7809950 0.678 rs2395868 chr7:106897500 C/T cg23024343 chr7:107201750 COG5 0.43 5.93 0.47 2.78e-8 Coronary artery disease; TGCT cis rs910316 0.737 rs175043 chr14:75471803 G/A cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.38e-7 Height; TGCT cis rs17253792 0.822 rs79618862 chr14:56093971 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs3015497 1.000 rs4075253 chr14:51107737 G/A cg04730355 chr14:51134070 SAV1 -0.51 -4.59 -0.38 1.08e-5 Mean platelet volume; TGCT trans rs7618501 1.000 rs4855867 chr3:49745822 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs12579753 0.917 rs7138533 chr12:82187885 C/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg06238570 chr21:40685208 BRWD1 -0.8 -8.75 -0.62 1.29e-14 Cognitive function; TGCT cis rs4665809 0.941 rs1434079 chr2:26284670 C/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs637571 0.558 rs10896064 chr11:65641033 G/C cg26695010 chr11:65641043 EFEMP2 0.61 6.22 0.49 6.86e-9 Eosinophil percentage of white cells; TGCT cis rs877282 0.945 rs35342920 chr10:790484 T/C cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs2299587 0.554 rs2073562 chr8:17742929 A/G cg04898035 chr8:17640624 MTUS1 -0.2 -4.67 -0.39 7.77e-6 Economic and political preferences; TGCT cis rs981844 0.961 rs6827685 chr4:154662227 C/T cg14289246 chr4:154710475 SFRP2 1.0 8.35 0.6 1.17e-13 Response to statins (LDL cholesterol change); TGCT cis rs2836974 0.644 rs1882779 chr21:40690938 T/C cg11644478 chr21:40555479 PSMG1 -0.55 -4.77 -0.39 5.08e-6 Cognitive function; TGCT cis rs4953076 0.573 rs67537903 chr2:44422111 G/A cg04920474 chr2:44395004 PPM1B 0.58 5.71 0.46 7.87e-8 Height; TGCT cis rs6460942 0.915 rs17444141 chr7:12460971 T/G cg06484146 chr7:12443880 VWDE -0.57 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT cis rs7674212 0.510 rs2720468 chr4:104085153 A/G cg16532752 chr4:104119610 CENPE -0.58 -5.37 -0.43 3.66e-7 Type 2 diabetes; TGCT cis rs7552404 1.000 rs7513559 chr1:76173744 A/G cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1577917 0.916 rs4706252 chr6:86555180 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs6684514 1.000 rs11264468 chr1:156274585 C/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1990950 0.692 rs6885845 chr5:156859610 G/C cg25387487 chr5:157003181 ADAM19 0.31 4.78 0.39 4.78e-6 Lung function (FEV1/FVC); TGCT cis rs9640161 0.750 rs3800780 chr7:150027284 C/A cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 8.99e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs7666738 0.716 rs13136721 chr4:99085602 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.5 0.44 2.07e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg08280861 chr8:58055591 NA 0.49 5.76 0.46 6.39e-8 Developmental language disorder (linguistic errors); TGCT cis rs7586879 0.558 rs6718510 chr2:25122323 A/C cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs1903068 1.000 rs4516787 chr4:56010165 C/T cg01777861 chr4:56023843 NA -0.55 -6.5 -0.5 1.72e-9 Endometriosis; TGCT cis rs17401966 0.898 rs12117635 chr1:10317445 C/T cg19773385 chr1:10388646 KIF1B -0.21 -4.73 -0.39 6e-6 Hepatocellular carcinoma; TGCT cis rs7267979 0.903 rs2500423 chr20:25374882 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 4.69 0.39 7.21e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7833790 0.700 rs7825180 chr8:82723991 T/A cg17211192 chr8:82754475 SNX16 -0.95 -8.83 -0.62 8.45e-15 Diastolic blood pressure; TGCT cis rs6545883 0.931 rs12713437 chr2:61722904 C/T cg15711740 chr2:61764176 XPO1 -0.54 -4.95 -0.41 2.39e-6 Tuberculosis; TGCT cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg08645402 chr16:4508243 NA 0.2 5.01 0.41 1.86e-6 Schizophrenia; TGCT cis rs2073300 1.000 rs6137957 chr20:23437384 G/A cg09953122 chr20:23471693 CST8 -0.66 -4.64 -0.38 8.6e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7917772 0.636 rs2482499 chr10:104516246 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.59 4.79 0.39 4.77e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.51 -4.95 -0.41 2.34e-6 Prudent dietary pattern; TGCT cis rs6430585 0.697 rs7607174 chr2:136513670 T/A cg07169764 chr2:136633963 MCM6 1.2 11.43 0.72 4.14e-21 Corneal structure; TGCT cis rs7949030 0.626 rs11231145 chr11:62328854 G/A cg22862634 chr11:62369728 EML3;MTA2 0.71 9.07 0.63 2.23e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs968451 0.865 rs2076125 chr22:39711351 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.83 8.32 0.6 1.31e-13 Primary biliary cholangitis; TGCT cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg05785598 chr3:49045655 WDR6 0.36 4.84 0.4 3.82e-6 Menarche (age at onset); TGCT cis rs6089829 0.962 rs6122352 chr20:61668284 T/C cg08045932 chr20:61659980 NA 0.48 9.24 0.64 8.5e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs28595532 0.925 rs28627331 chr4:119665345 T/C cg21605333 chr4:119757512 SEC24D 1.4 7.94 0.58 1.04e-12 Cannabis dependence symptom count; TGCT cis rs617219 0.710 rs6874525 chr5:78574237 C/T cg23987322 chr5:78407566 BHMT -0.35 -4.69 -0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7666738 0.830 rs7678567 chr4:99057346 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg07061783 chr6:25882402 NA -0.5 -5.4 -0.44 3.29e-7 Blood metabolite levels; TGCT cis rs7945705 0.934 rs1988709 chr11:8882890 A/T cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.94 0.41 2.5e-6 Hemoglobin concentration; TGCT cis rs8017423 0.967 rs11844225 chr14:90726676 G/A cg04374321 chr14:90722782 PSMC1 0.76 7.88 0.58 1.44e-12 Mortality in heart failure; TGCT cis rs3960554 0.569 rs4728618 chr7:75865059 T/C cg19105122 chr7:75896889 SRRM3 0.6 5.01 0.41 1.86e-6 Eotaxin levels; TGCT cis rs8179 0.645 rs11765954 chr7:92280695 A/G cg15732164 chr7:92237376 CDK6 -0.3 -5.35 -0.43 4.14e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs1577917 0.958 rs12198876 chr6:86525476 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.46 -0.44 2.47e-7 Response to antipsychotic treatment; TGCT cis rs929354 0.742 rs7785227 chr7:156999297 C/T cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs709400 0.663 rs17617941 chr14:103953032 T/C cg26031613 chr14:104095156 KLC1 0.85 9.5 0.65 2.07e-16 Body mass index; TGCT cis rs2895526 1.000 rs2895526 chr10:12726061 A/T cg18283737 chr10:12085149 UPF2 0.45 4.48 0.37 1.64e-5 Headache; TGCT cis rs597539 0.652 rs516425 chr11:68715675 G/A cg21963583 chr11:68658836 MRPL21 0.36 6.02 0.48 1.81e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17221829 0.739 rs7945443 chr11:89372622 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs2730245 0.550 rs2657364 chr7:158683825 T/C cg11984989 chr7:158649758 WDR60 1.02 9.51 0.65 1.95e-16 Height; TGCT cis rs2235642 0.787 rs2235646 chr16:1601287 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.32 -5.73 -0.46 7.16e-8 Coronary artery disease; TGCT cis rs5769765 1.000 rs5770741 chr22:50270215 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs6988636 1.000 rs4282551 chr8:124185916 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs3796352 1.000 rs11717619 chr3:53003179 A/C cg07884673 chr3:53033167 SFMBT1 0.62 6.19 0.49 8.26e-9 Immune reponse to smallpox (secreted IL-2); TGCT trans rs2688608 0.592 rs11000758 chr10:75493610 A/T cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs1949733 0.655 rs2631736 chr4:8478421 C/G cg13073564 chr4:8508604 NA 0.43 4.74 0.39 5.8e-6 Response to antineoplastic agents; TGCT cis rs4595586 0.545 rs12809206 chr12:39388748 A/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs1729951 0.575 rs747842 chr3:136703121 A/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs1552244 0.507 rs6443274 chr3:9995288 A/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.32 -4.85 -0.4 3.57e-6 Alzheimer's disease; TGCT cis rs11077998 0.933 rs4239021 chr17:80531826 T/C cg10255544 chr17:80519551 FOXK2 0.23 4.44 0.37 1.96e-5 Reticulocyte fraction of red cells; TGCT cis rs6951245 0.554 rs10270249 chr7:1151886 G/T cg23708337 chr7:1209742 NA 0.44 4.99 0.41 2e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3820068 0.705 rs58424111 chr1:15868470 A/C cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs12477438 0.798 rs2045057 chr2:99684929 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs8177253 0.965 rs4854761 chr3:133498789 A/G cg16414030 chr3:133502952 NA 0.63 9.94 0.67 1.8e-17 Iron status biomarkers; TGCT cis rs3008870 1.000 rs3008855 chr1:67386204 A/G cg03991309 chr1:68237761 GNG12 -0.27 -4.6 -0.38 1.04e-5 Lymphocyte percentage of white cells; TGCT cis rs2204008 0.805 rs7296063 chr12:37964775 T/G cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs789852 0.867 rs708632 chr3:194325325 C/T cg18000598 chr3:194342907 TMEM44 -0.81 -5.27 -0.43 5.87e-7 QT interval; TGCT cis rs1577917 0.570 rs114854865 chr6:86554236 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs1580019 0.587 rs6951955 chr7:32548761 A/T cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.15 0.79 1.17e-27 Cognitive ability; TGCT cis rs9486719 1.000 rs72931061 chr6:96880285 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs9653442 0.545 rs4851252 chr2:100757280 C/T cg22139774 chr2:100720529 AFF3 -0.38 -5.82 -0.46 4.68e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs736408 0.522 rs11130310 chr3:52674667 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg03395511 chr6:291903 DUSP22 -0.7 -7.09 -0.54 9.19e-11 Menopause (age at onset); TGCT cis rs6671200 0.831 rs9659908 chr1:95656127 C/T cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs72615157 0.634 rs74742883 chr7:99785765 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.61 4.99 0.41 1.98e-6 Lung function (FEV1/FVC); TGCT cis rs12893668 0.616 rs58033365 chr14:104030901 T/C cg26031613 chr14:104095156 KLC1 -0.54 -4.45 -0.37 1.88e-5 Reticulocyte count; TGCT cis rs1218582 0.741 rs11264281 chr1:154867221 A/G cg24250549 chr1:154909240 PMVK 0.57 5.36 0.43 3.88e-7 Prostate cancer; TGCT cis rs73815153 0.744 rs7712571 chr5:180463033 A/G cg00299286 chr5:180478185 BTNL9 0.86 4.95 0.41 2.36e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs7937612 1.000 rs894839 chr11:120337705 A/G cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.61 -0.38 9.71e-6 Intraocular pressure; TGCT cis rs2710642 0.962 rs7557501 chr2:63086639 C/T cg17519650 chr2:63277830 OTX1 0.64 5.94 0.47 2.7e-8 LDL cholesterol levels;LDL cholesterol; TGCT cis rs3011225 0.710 rs3011222 chr1:44317545 C/T cg12908607 chr1:44402522 ARTN -0.64 -7.74 -0.57 3e-12 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs918629 0.679 rs6883880 chr5:95271173 A/T cg16656078 chr5:95278638 ELL2 -0.28 -4.55 -0.38 1.25e-5 IgG glycosylation; TGCT cis rs2637266 1.000 rs2579749 chr10:78332105 T/C cg18941641 chr10:78392320 NA 0.4 4.98 0.41 2.09e-6 Pulmonary function; TGCT cis rs2836974 0.644 rs61300849 chr21:40680194 G/A cg06238570 chr21:40685208 BRWD1 -0.8 -9.08 -0.63 2.07e-15 Cognitive function; TGCT cis rs4727027 0.866 rs35599790 chr7:148806012 C/T cg23583168 chr7:148888333 NA -0.72 -9.16 -0.64 1.34e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7617773 0.925 rs6442105 chr3:48182326 A/G cg11946769 chr3:48343235 NME6 -0.59 -5.36 -0.43 3.96e-7 Coronary artery disease; TGCT cis rs34526934 0.566 rs9141 chr2:177037970 T/C cg23561606 chr2:177418561 NA -0.45 -4.47 -0.37 1.71e-5 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs9436747 0.641 rs1343981 chr1:66045328 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.65 0.39 8.37e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs4900538 0.855 rs72698602 chr14:102880454 T/C cg18135206 chr14:102964638 TECPR2 -0.2 -4.53 -0.38 1.39e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT trans rs1814175 0.817 rs11040700 chr11:50023832 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg04317338 chr11:64019027 PLCB3 0.76 6.27 0.49 5.45e-9 Mean platelet volume; TGCT cis rs700651 0.789 rs6434949 chr2:198855510 T/A cg00792783 chr2:198669748 PLCL1 0.57 5.1 0.42 1.24e-6 Intracranial aneurysm; TGCT cis rs11785400 1.000 rs11785400 chr8:143730456 C/T cg10596483 chr8:143751796 JRK 0.54 5.77 0.46 5.95e-8 Schizophrenia; TGCT cis rs9818758 0.607 rs11719220 chr3:49245201 A/G cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg00024416 chr22:24240387 NA -0.25 -4.65 -0.39 8.31e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7312933 0.618 rs12366848 chr12:42682215 A/G cg19980929 chr12:42632907 YAF2 0.41 5.61 0.45 1.26e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7959452 0.535 rs1350166 chr12:69636314 G/T cg11871910 chr12:69753446 YEATS4 0.62 6.2 0.49 7.84e-9 Blood protein levels; TGCT cis rs13326165 0.760 rs11714402 chr3:52391735 G/T cg07884673 chr3:53033167 SFMBT1 -0.35 -4.56 -0.38 1.21e-5 HDL cholesterol;HDL cholesterol levels; TGCT cis rs9467711 0.606 rs9393714 chr6:26373740 G/T cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4665809 0.941 rs41285975 chr2:26351144 T/C cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs4665809 0.652 rs6727974 chr2:26524639 A/G cg26119090 chr2:26468346 HADHA;HADHB 0.9 6.65 0.51 8.41e-10 Gut microbiome composition (summer); TGCT cis rs969930 0.526 rs4738043 chr8:70775307 T/A cg03719092 chr8:70744881 SLCO5A1 -0.47 -5.04 -0.41 1.6e-6 Lower body strength; TGCT cis rs7312933 0.558 rs11181502 chr12:42823833 A/G cg19980929 chr12:42632907 YAF2 0.42 5.91 0.47 3.05e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6500602 0.793 rs4785964 chr16:4484613 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.38 4.7 0.39 6.78e-6 Schizophrenia; TGCT trans rs7618501 1.000 rs4855867 chr3:49745822 C/T cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs929354 0.742 rs2051877 chr7:157008813 A/T cg05182265 chr7:156933206 UBE3C -0.41 -9.16 -0.64 1.33e-15 Body mass index; TGCT cis rs35146811 0.735 rs1637001 chr7:99808151 G/A cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs1372520 0.684 rs2197120 chr4:90729602 A/G cg01966878 chr4:90757139 SNCA -0.31 -4.84 -0.4 3.8e-6 Neuroticism; TGCT cis rs7089973 0.872 rs7072364 chr10:116620840 G/A cg03647239 chr10:116582469 FAM160B1 0.53 4.73 0.39 6.08e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs4689388 0.853 rs13108780 chr4:6294630 A/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9811920 0.535 rs792831 chr3:99473720 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.39 4.6 0.38 1.04e-5 Axial length; TGCT cis rs514406 0.763 rs7535088 chr1:53215042 A/G cg08859206 chr1:53392774 SCP2 0.4 5.88 0.47 3.56e-8 Monocyte count; TGCT cis rs3770081 0.536 rs7562837 chr2:86306251 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -1.1 -6.55 -0.51 1.38e-9 Facial emotion recognition (sad faces); TGCT cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg23758822 chr17:41437982 NA 0.67 6.68 0.51 7.33e-10 Menopause (age at onset); TGCT cis rs1008375 0.800 rs10008598 chr4:17607323 T/C cg10189774 chr4:17578691 LAP3 0.65 5.53 0.44 1.84e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11673344 0.523 rs8108509 chr19:37551272 T/C cg08039142 chr19:36980659 ZNF566 0.5 4.62 0.38 9.48e-6 Obesity-related traits; TGCT cis rs2836950 0.502 rs2150411 chr21:40574552 G/T cg11644478 chr21:40555479 PSMG1 -0.49 -4.57 -0.38 1.17e-5 Menarche (age at onset); TGCT cis rs9457247 0.508 rs6902119 chr6:167505791 T/C cg07741184 chr6:167504864 NA 0.27 5.25 0.43 6.4e-7 Crohn's disease; TGCT cis rs2739330 0.734 rs2000467 chr22:24241533 C/T cg18538332 chr22:24372958 LOC391322 1.04 11.73 0.73 7.89e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7731657 0.537 rs12516770 chr5:130222575 T/C cg08523029 chr5:130500466 HINT1 -0.6 -5.0 -0.41 1.92e-6 Fasting plasma glucose; TGCT cis rs3771570 1.000 rs1056801 chr2:242292307 T/C cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs13108904 0.539 rs13140926 chr4:1340939 G/A cg00684032 chr4:1343700 KIAA1530 0.24 4.91 0.4 2.82e-6 Obesity-related traits; TGCT cis rs8017423 1.000 rs1959001 chr14:90667739 G/A cg04374321 chr14:90722782 PSMC1 0.77 7.96 0.58 9.31e-13 Mortality in heart failure; TGCT cis rs1568657 0.666 rs55751241 chr15:83752643 T/C cg05615147 chr15:83735916 BTBD1 -0.6 -4.9 -0.4 2.95e-6 Kawasaki disease; TGCT cis rs67311347 1.000 rs12494022 chr3:40426652 A/C cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs6665290 0.901 rs7535826 chr1:227213968 A/C cg10327440 chr1:227177885 CDC42BPA 0.9 16.32 0.83 1.16e-32 Myeloid white cell count; TGCT cis rs875971 0.862 rs6460302 chr7:65960257 C/G cg11764359 chr7:65958608 NA 0.56 5.0 0.41 1.92e-6 Aortic root size; TGCT cis rs9611565 0.512 rs5996063 chr22:42168767 G/A cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs12048904 0.964 rs17123467 chr1:101331760 G/A cg16556008 chr1:101360663 SLC30A7;EXTL2 0.55 5.14 0.42 1.04e-6 Multiple sclerosis; TGCT cis rs2295359 0.824 rs4655679 chr1:67599657 A/G cg08029281 chr1:67600428 NA -0.38 -4.46 -0.37 1.85e-5 Psoriasis; TGCT cis rs13064447 0.874 rs13058951 chr3:12752381 C/T cg20675869 chr3:12750130 NA 0.18 4.59 0.38 1.08e-5 Major depression and alcohol dependence; TGCT cis rs765787 0.556 rs2413778 chr15:45539397 C/A cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs7246657 0.653 rs4805207 chr19:37673733 G/A cg24025825 chr19:37761650 NA -0.32 -5.02 -0.41 1.79e-6 Coronary artery calcification; TGCT cis rs10791097 0.694 rs10791100 chr11:130738946 T/A cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg09904177 chr6:26538194 HMGN4 0.66 6.33 0.49 3.99e-9 Intelligence (multi-trait analysis); TGCT cis rs7586879 0.575 rs6721750 chr2:25128719 A/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs12627970 0.565 rs2072872 chr22:39713128 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.88 11.02 0.7 4.09e-20 Inflammatory bowel disease; TGCT cis rs8050907 0.744 rs1362625 chr16:4526310 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs35306767 0.855 rs2050944 chr10:918910 T/C cg26597838 chr10:835615 NA 0.75 10.56 0.69 5.62e-19 Eosinophil percentage of granulocytes; TGCT trans rs561341 1.000 rs111454793 chr17:30319267 T/C cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs6964587 0.967 rs12538325 chr7:91757479 A/G cg17063962 chr7:91808500 NA 0.89 9.39 0.64 3.84e-16 Breast cancer; TGCT cis rs6032067 0.598 rs2741500 chr20:43944958 G/T cg20256260 chr20:43936981 MATN4;RBPJL -0.32 -4.72 -0.39 6.35e-6 Blood protein levels; TGCT cis rs3806843 0.548 rs246038 chr5:140331699 A/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT trans rs1005277 0.522 rs289649 chr10:37975384 T/C cg17830980 chr10:43048298 ZNF37B -0.66 -7.47 -0.56 1.22e-11 Extrinsic epigenetic age acceleration; TGCT cis rs7666738 0.830 rs6848404 chr4:98946750 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg05665937 chr4:1216051 CTBP1 0.22 4.47 0.37 1.75e-5 Obesity-related traits; TGCT cis rs66573146 1.000 rs55672215 chr4:6970529 T/C cg00086871 chr4:6988644 TBC1D14 0.89 4.51 0.38 1.47e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs67073037 0.955 rs4665437 chr2:29171381 A/G cg09522027 chr2:28974177 PPP1CB -0.57 -4.49 -0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs6570726 0.935 rs425717 chr6:145838620 A/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.716 rs6817529 chr4:99023213 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2295359 0.892 rs6688383 chr1:67655954 C/T cg08029281 chr1:67600428 NA -0.41 -4.73 -0.39 5.91e-6 Psoriasis; TGCT cis rs12210905 1.000 rs6902012 chr6:27243767 C/T cg08851530 chr6:28072375 NA -1.16 -5.14 -0.42 1.02e-6 Hip circumference adjusted for BMI; TGCT cis rs9486715 1.000 rs9486725 chr6:97061159 C/T cg18709589 chr6:96969512 KIAA0776 -0.81 -7.71 -0.57 3.5e-12 Headache; TGCT cis rs7617480 0.648 rs4858830 chr3:48734002 T/C cg07636037 chr3:49044803 WDR6 0.77 6.37 0.5 3.33e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs9486719 1.000 rs11756315 chr6:97008678 A/G cg18709589 chr6:96969512 KIAA0776 0.67 4.84 0.4 3.85e-6 Migraine;Coronary artery disease; TGCT cis rs3862260 0.509 rs10923879 chr1:120163831 A/G cg16322792 chr1:120165303 ZNF697 0.35 8.4 0.6 8.92e-14 Systemic lupus erythematosus; TGCT cis rs2832191 0.791 rs7282843 chr21:30475226 A/G cg08807101 chr21:30365312 RNF160 0.64 6.01 0.48 1.91e-8 Dental caries; TGCT cis rs2721195 1.000 rs2721195 chr8:145677011 T/C cg15857475 chr8:145742913 RECQL4;LRRC14 -0.8 -8.29 -0.6 1.61e-13 Age at first birth; TGCT cis rs6671200 0.573 rs3820345 chr1:95713175 C/T cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT trans rs6089829 0.962 rs6011544 chr20:61658782 T/C cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs12579753 1.000 rs7300900 chr12:82166821 G/T cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.775 rs17805026 chr8:58160637 A/C cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs12478296 1.000 rs6739247 chr2:243039189 C/A cg06360820 chr2:242988706 NA -0.58 -4.47 -0.37 1.76e-5 Obesity-related traits; TGCT cis rs769267 0.930 rs1047361 chr19:19606634 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs892961 0.867 rs1079354 chr17:75415713 C/T cg05865280 chr17:75406074 SEPT9 0.29 6.78 0.52 4.27e-10 Airflow obstruction; TGCT cis rs4252435 0.614 rs10265881 chr7:142602578 G/A cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs2832191 0.720 rs2832194 chr21:30494250 T/C cg24692254 chr21:30365293 RNF160 -0.92 -9.97 -0.67 1.45e-17 Dental caries; TGCT cis rs4862307 0.733 rs7686028 chr4:184994669 T/C cg06737308 chr4:185021514 ENPP6 -0.34 -4.83 -0.4 4e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs11658309 1 rs11658309 chr17:17762247 T/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.78 -0.39 4.77e-6 Strep throat; TGCT cis rs875971 0.628 rs6974355 chr7:65841981 A/G cg18876405 chr7:65276391 NA 0.41 6.33 0.49 3.99e-9 Aortic root size; TGCT cis rs7226408 0.857 rs2121023 chr18:34488414 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1153858 0.943 rs1145079 chr15:45681761 T/C cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs7824557 0.569 rs7816601 chr8:11205593 T/C cg21775007 chr8:11205619 TDH 0.71 6.7 0.52 6.36e-10 Retinal vascular caliber; TGCT cis rs9435341 0.965 rs9435441 chr1:107603330 C/G cg09367891 chr1:107599246 PRMT6 -0.63 -5.42 -0.44 3.03e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs28386778 0.687 rs59596917 chr17:61806264 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs11098499 0.754 rs1511017 chr4:120250805 G/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs6547741 0.967 rs4665995 chr2:27813827 T/G cg27432699 chr2:27873401 GPN1 0.18 4.65 0.38 8.53e-6 Oral cavity cancer; TGCT cis rs593982 0.777 rs72941015 chr11:65457514 A/C cg08755490 chr11:65554678 OVOL1 -1.26 -6.96 -0.53 1.71e-10 Atopic dermatitis; TGCT cis rs4951018 0.853 rs1573104 chr1:205636907 A/C cg24503407 chr1:205819492 PM20D1 -0.36 -4.62 -0.38 9.63e-6 Prostate-specific antigen levels; TGCT cis rs9916302 0.898 rs8072297 chr17:37478048 A/T cg07936489 chr17:37558343 FBXL20 0.6 4.53 0.38 1.38e-5 Glomerular filtration rate (creatinine); TGCT cis rs12541335 0.579 rs59283125 chr8:22212311 G/A cg02463440 chr8:22132932 PIWIL2 0.27 5.21 0.42 7.67e-7 Hypertriglyceridemia; TGCT cis rs17253792 0.732 rs79014965 chr14:56117551 T/G cg01858014 chr14:56050164 KTN1 -0.35 -4.47 -0.37 1.71e-5 Putamen volume; TGCT cis rs1552244 0.882 rs13099136 chr3:10031431 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs1799949 0.965 rs8176140 chr17:41251646 T/A cg23758822 chr17:41437982 NA 0.72 6.85 0.52 3.09e-10 Menopause (age at onset); TGCT cis rs644799 0.648 rs1255181 chr11:95472148 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.48 4.78 0.39 4.88e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs71435601 0.628 rs525172 chr2:21382976 T/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg16145915 chr7:1198662 ZFAND2A -0.54 -7.01 -0.53 1.37e-10 Longevity;Endometriosis; TGCT cis rs2147959 0.766 rs10753451 chr1:228715019 G/T cg22700015 chr1:228743131 NA -0.63 -5.26 -0.43 6.17e-7 Adult asthma; TGCT cis rs1552244 1.000 rs7619340 chr3:10108178 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs42648 0.869 rs1134956 chr7:89938680 C/T cg25739043 chr7:89950458 NA -0.71 -7.09 -0.54 8.84e-11 Homocysteine levels; TGCT cis rs4689388 0.890 rs4689397 chr4:6299387 G/A cg00701064 chr4:6280414 WFS1 0.44 5.81 0.46 4.99e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2197308 0.669 rs11173675 chr12:38091486 A/G cg26384229 chr12:38710491 ALG10B 0.59 5.11 0.42 1.19e-6 Morning vs. evening chronotype; TGCT cis rs1153858 1.000 rs2467863 chr15:45641880 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.82 0.46 4.73e-8 Homoarginine levels; TGCT cis rs854765 0.964 rs2230316 chr17:17997209 C/T cg04398451 chr17:18023971 MYO15A 0.3 4.77 0.39 5.02e-6 Total body bone mineral density; TGCT cis rs4808199 0.947 rs2163804 chr19:19575965 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.73 5.16 0.42 9.65e-7 Nonalcoholic fatty liver disease; TGCT cis rs1801251 0.752 rs2675966 chr2:233735543 T/C cg25237894 chr2:233734115 C2orf82 -0.29 -5.63 -0.45 1.14e-7 Coronary artery disease; TGCT cis rs3138083 0.623 rs3138087 chr9:35645779 C/A cg07116010 chr9:35646325 NA 0.84 10.25 0.68 3.08e-18 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel); TGCT cis rs6088580 0.634 rs2378133 chr20:32919505 C/G cg06115741 chr20:33292138 TP53INP2 -0.54 -4.74 -0.39 5.7e-6 Glomerular filtration rate (creatinine); TGCT cis rs67311347 1.000 rs7625736 chr3:40441345 C/G cg17264618 chr3:40429014 ENTPD3 -0.31 -4.59 -0.38 1.08e-5 Renal cell carcinoma; TGCT cis rs9926296 0.682 rs467357 chr16:89717397 A/G cg03388025 chr16:89894329 SPIRE2 -0.35 -5.05 -0.41 1.53e-6 Vitiligo; TGCT cis rs2032447 0.714 rs199725 chr6:25953684 A/G cg03517284 chr6:25882590 NA -0.64 -5.49 -0.44 2.17e-7 Intelligence (multi-trait analysis); TGCT cis rs9372253 1.000 rs9372253 chr6:110716136 C/T cg00083206 chr6:110721305 DDO -0.43 -6.46 -0.5 2.2e-9 Platelet distribution width; TGCT cis rs12643440 0.538 rs16894433 chr4:17143112 A/C cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg11062466 chr8:58055876 NA 0.38 4.5 0.37 1.56e-5 Developmental language disorder (linguistic errors); TGCT trans rs4650994 0.525 rs2493858 chr1:178541210 A/G cg05059571 chr16:84539110 KIAA1609 -0.54 -11.16 -0.71 1.91e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs34638657 0.500 rs7405197 chr16:82169833 C/A cg09439754 chr16:82129088 HSD17B2 -0.24 -4.86 -0.4 3.51e-6 Lung adenocarcinoma; TGCT cis rs6540559 0.611 rs11810817 chr1:210011747 C/G cg21951975 chr1:209979733 IRF6 0.63 4.76 0.39 5.36e-6 Cleft lip with or without cleft palate; TGCT cis rs806215 0.526 rs62481450 chr7:127568983 C/T cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.37e-6 Type 2 diabetes; TGCT cis rs597539 0.652 rs553875 chr11:68695144 T/G cg06112835 chr11:68658793 MRPL21 0.46 7.8 0.57 2.18e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10193935 1.000 rs13424523 chr2:42413562 T/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4253772 0.515 rs6008591 chr22:46703664 T/C cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9911578 0.757 rs4793954 chr17:56629527 G/T cg12560992 chr17:57184187 TRIM37 -0.73 -7.23 -0.54 4.32e-11 Intelligence (multi-trait analysis); TGCT cis rs907683 0.584 rs2070927 chr2:220282955 C/T cg15015639 chr2:220282977 DES 0.37 4.77 0.39 5.05e-6 Resting heart rate; TGCT cis rs9611565 0.512 rs139562 chr22:42196684 G/C cg13695892 chr22:41940480 POLR3H -0.83 -7.77 -0.57 2.51e-12 Vitiligo; TGCT cis rs4805272 0.962 rs4805277 chr19:29330943 C/G cg15000279 chr19:29285009 NA -0.51 -5.65 -0.45 1.04e-7 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs6136489 0.583 rs6136477 chr20:1922534 G/C cg17747171 chr20:2633605 NOP56;SNORD110 0.54 4.75 0.39 5.46e-6 Platelet distribution width;Mean platelet volume; TGCT cis rs3791556 1.000 rs3791556 chr2:240112972 G/A cg03281426 chr2:240109471 HDAC4 0.28 4.46 0.37 1.82e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs28595532 0.920 rs17258050 chr4:119672019 G/A cg14228332 chr4:119757509 SEC24D 1.06 5.67 0.45 9.69e-8 Cannabis dependence symptom count; TGCT cis rs79349575 0.749 rs1057902 chr17:47005588 C/T cg27201301 chr17:47039149 GIP 0.26 4.63 0.38 9.2e-6 Type 2 diabetes; TGCT cis rs9915657 0.870 rs918081 chr17:70127808 G/A cg06234051 chr17:70120541 SOX9 -0.26 -5.28 -0.43 5.57e-7 Thyroid hormone levels; TGCT cis rs79976124 0.797 rs74995761 chr6:66640216 G/A cg07460842 chr6:66804631 NA 0.57 5.09 0.42 1.26e-6 Type 2 diabetes; TGCT cis rs2120019 0.938 rs35911108 chr15:75322179 G/A cg17294928 chr15:75287854 SCAMP5 -0.79 -6.27 -0.49 5.46e-9 Blood trace element (Zn levels); TGCT cis rs3806843 0.583 rs408652 chr5:140330013 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.42 -5.24 -0.43 6.76e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs4252435 0.520 rs76184304 chr7:142633490 C/G cg09833174 chr7:143059591 FAM131B -1.03 -4.71 -0.39 6.56e-6 Cancer; TGCT cis rs748404 0.631 rs8042688 chr15:43638525 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs5769707 0.967 rs763126 chr22:49988574 G/T cg10356904 chr22:49881777 NA 0.23 4.68 0.39 7.36e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs17741873 0.836 rs2254266 chr10:75601688 T/C cg07699608 chr10:75541558 CHCHD1 0.69 4.87 0.4 3.27e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs7568458 0.837 rs3770098 chr2:85805367 C/A cg02493740 chr2:85810744 VAMP5 -0.27 -4.85 -0.4 3.63e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs910316 1.000 rs3742773 chr14:75579643 A/G cg08847533 chr14:75593920 NEK9 0.95 10.61 0.69 4.09e-19 Height; TGCT cis rs7772486 0.686 rs9399565 chr6:146081906 G/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.7 -0.39 6.74e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1031925 0.640 rs4687775 chr3:51769206 A/C cg10583097 chr3:51429234 RBM15B 0.55 5.07 0.41 1.42e-6 Melanoma; TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs854765 0.583 rs8070128 chr17:17804725 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.61 -0.45 1.24e-7 Total body bone mineral density; TGCT cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg06112835 chr11:68658793 MRPL21 0.46 8.12 0.59 3.91e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2228479 0.850 rs74251568 chr16:89903416 A/C cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs66561647 0.895 rs9649959 chr8:128972721 C/T cg11792826 chr8:129160931 MIR1208 -0.19 -4.49 -0.37 1.6e-5 Hemoglobin concentration; TGCT cis rs2963155 0.518 rs10482614 chr5:142782402 C/T cg17617527 chr5:142782415 NR3C1 0.86 5.51 0.44 2.02e-7 Breast cancer; TGCT cis rs12510870 0.599 rs13144296 chr4:74453988 A/G cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs9733 0.519 rs11807450 chr1:150677719 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.55 0.38 1.24e-5 Tonsillectomy; TGCT cis rs933688 1.000 rs6865495 chr5:90746424 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.93 8.39 0.6 9.04e-14 Smoking behavior; TGCT cis rs10197940 0.545 rs2444267 chr2:152308611 T/G cg19508488 chr2:152266495 RIF1 0.59 4.94 0.41 2.52e-6 Lung cancer; TGCT cis rs4731207 0.596 rs12537431 chr7:124586556 G/A cg10503827 chr7:124401702 GPR37 -0.21 -4.53 -0.38 1.37e-5 Cutaneous malignant melanoma; TGCT cis rs477895 1.000 rs41294396 chr11:64078581 G/A cg23719950 chr11:63933701 MACROD1 -0.59 -4.6 -0.38 1.01e-5 Mean platelet volume; TGCT cis rs981844 1.000 rs2606335 chr4:154656536 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs10465746 0.967 rs12407641 chr1:84368115 T/C cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs1552244 1.000 rs17032278 chr3:10077955 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs7829975 0.774 rs1039915 chr8:8679614 T/C cg08975724 chr8:8085496 FLJ10661 0.53 4.74 0.39 5.88e-6 Mood instability; TGCT cis rs7927771 0.832 rs7105851 chr11:47383275 T/C cg21462715 chr11:47870315 NUP160 -0.57 -4.63 -0.38 9.08e-6 Subjective well-being; TGCT cis rs6714710 0.580 rs11690737 chr2:98461953 C/T cg26665480 chr2:98280029 ACTR1B 0.66 6.18 0.49 8.38e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs10927875 0.597 rs61782184 chr1:16150976 G/A cg21385522 chr1:16154831 NA -1.0 -17.44 -0.84 3.61e-35 Dilated cardiomyopathy; TGCT cis rs2836974 0.932 rs56306759 chr21:40608106 G/A cg11644478 chr21:40555479 PSMG1 1.0 10.6 0.69 4.32e-19 Cognitive function; TGCT cis rs9443189 0.570 rs7755068 chr6:76405700 A/G cg01950844 chr6:76311363 SENP6 1.0 6.24 0.49 6.35e-9 Prostate cancer; TGCT cis rs992157 0.710 rs10169718 chr2:219103580 C/T cg00012203 chr2:219082015 ARPC2 -0.81 -9.9 -0.66 2.21e-17 Colorectal cancer; TGCT cis rs447921 0.861 rs17596582 chr17:74438120 A/T cg09812376 chr17:74270190 QRICH2 0.42 4.49 0.37 1.6e-5 Mitochondrial DNA levels; TGCT cis rs2288073 0.896 rs13404513 chr2:24410780 G/A cg02683114 chr2:24398427 C2orf84 -0.24 -5.72 -0.46 7.53e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs7267979 1.000 rs4815409 chr20:25346697 C/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12291225 0.585 rs12270374 chr11:14375079 T/C cg19336497 chr11:14380999 RRAS2 -0.43 -7.02 -0.53 1.3100000000000001e-10 Sense of smell; TGCT cis rs362272 0.545 rs2749782 chr4:3339761 A/G cg18352616 chr4:3374830 RGS12 0.24 4.89 0.4 3.02e-6 Serum sulfate level; TGCT cis rs6681544 0.760 rs7413275 chr1:82417552 T/G cg04226724 chr1:82268649 LPHN2 -0.46 -4.68 -0.39 7.4e-6 Metabolite levels (X-11787); TGCT cis rs289997 0.777 rs73277029 chr7:25591710 C/T cg14064488 chr7:26331273 SNX10 -0.34 -4.54 -0.38 1.33e-5 Breast cancer; TGCT trans rs10435719 0.780 rs9692662 chr8:11789863 C/T cg15556689 chr8:8085844 FLJ10661 0.74 7.04 0.53 1.17e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs3774830 0.714 rs17464616 chr4:5465004 G/A cg26943120 chr4:5472116 STK32B 0.22 4.82 0.4 4.15e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2836950 0.545 rs11701805 chr21:40618683 T/C cg06238570 chr21:40685208 BRWD1 -0.61 -6.2 -0.49 7.83e-9 Menarche (age at onset); TGCT cis rs597539 0.617 rs598353 chr11:68635770 C/A cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs76473307 1.000 rs117968747 chr20:57397505 A/G cg06163629 chr20:57414884 GNASAS;GNAS -0.67 -4.53 -0.38 1.34e-5 Chronic lymphocytic leukemia; TGCT cis rs4523957 0.614 rs2984941 chr17:2031543 A/G cg16513277 chr17:2031491 SMG6 -0.21 -4.74 -0.39 5.72e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9611565 0.607 rs132792 chr22:42062822 C/T cg03806693 chr22:41940476 POLR3H 0.95 9.44 0.65 2.92e-16 Vitiligo; TGCT cis rs2839186 0.508 rs6518278 chr21:47640571 A/G cg09417038 chr21:47716443 C21orf57 0.31 4.45 0.37 1.89e-5 Testicular germ cell tumor; TGCT cis rs11105298 0.891 rs10858872 chr12:89872932 C/T cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2243480 1.000 rs422164 chr7:65586605 C/G cg18252515 chr7:66147081 NA -1.22 -7.98 -0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs4665809 1.000 rs4665819 chr2:26309073 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs13315871 1.000 rs4362735 chr3:58429893 C/G cg12435725 chr3:58293450 RPP14 -0.44 -4.53 -0.38 1.37e-5 Cholesterol, total; TGCT cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg03351412 chr1:154909251 PMVK -0.53 -4.93 -0.4 2.6e-6 Prostate cancer; TGCT cis rs8056742 1.000 rs16975170 chr16:85092575 C/T cg04622164 chr16:85157906 NA 0.61 5.11 0.42 1.16e-6 Amyotrophic lateral sclerosis; TGCT cis rs2115630 0.936 rs11073663 chr15:85260268 A/G cg12501888 chr15:85177176 SCAND2 -0.49 -4.72 -0.39 6.39e-6 P wave terminal force; TGCT cis rs858239 0.633 rs858300 chr7:23244631 A/G cg05602783 chr7:23145260 KLHL7 -0.65 -5.47 -0.44 2.4e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs28595532 0.800 rs111626798 chr4:119352517 C/T cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs3785574 0.962 rs62077512 chr17:61851435 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.12 15.17 0.81 4.81e-30 Height; TGCT cis rs875971 0.895 rs10755833 chr7:65913917 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs6582630 0.598 rs10880614 chr12:38509766 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg05025164 chr4:1340916 KIAA1530 0.78 6.44 0.5 2.36e-9 Longevity; TGCT cis rs71636778 0.509 rs17360994 chr1:27278573 T/C cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs981844 1.000 rs62325092 chr4:154668674 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs10832169 1.000 rs10832169 chr11:14066486 G/A cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs3824867 0.920 rs3740685 chr11:47468791 C/T cg20307385 chr11:47447363 PSMC3 0.69 5.93 0.47 2.74e-8 Mean corpuscular hemoglobin; TGCT cis rs4799461 0.740 rs7506216 chr18:35125862 C/T cg27332583 chr18:35150602 NA 0.29 4.74 0.39 5.79e-6 Neuroticism; TGCT cis rs9394841 0.667 rs9471667 chr6:41776681 T/C cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs7647973 0.626 rs4855846 chr3:49683526 G/A cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs7578199 0.576 rs3771586 chr2:242401002 A/G cg21155796 chr2:242212141 HDLBP 0.51 4.63 0.38 9.19e-6 Chronic lymphocytic leukemia; TGCT cis rs7615952 0.736 rs13063122 chr3:125643860 G/A cg05084668 chr3:125655381 ALG1L -0.76 -6.21 -0.49 7.3e-9 Blood pressure (smoking interaction); TGCT cis rs713587 0.713 rs12618252 chr2:25207950 G/A cg01884057 chr2:25150051 NA -0.38 -7.81 -0.57 2.04e-12 Body mass index in non-asthmatics; TGCT cis rs35934224 0.831 rs13057374 chr22:19871097 C/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.34 -0.43 4.3e-7 Glaucoma (primary open-angle); TGCT cis rs909002 0.811 rs7545321 chr1:32122164 A/G cg11573219 chr1:32083031 HCRTR1 -0.43 -5.28 -0.43 5.52e-7 Intelligence (multi-trait analysis); TGCT cis rs9362426 1.000 rs242271 chr6:88082029 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.47 5.09 0.42 1.3e-6 Depressive episodes in bipolar disorder; TGCT cis rs6754311 0.731 rs309160 chr2:136685228 C/T cg07169764 chr2:136633963 MCM6 0.62 5.75 0.46 6.66e-8 Mosquito bite size; TGCT cis rs11190604 0.697 rs10748795 chr10:102194818 A/T cg16342193 chr10:102329863 NA 0.4 4.99 0.41 2.04e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs860554 0.660 rs832169 chr1:201256771 C/T cg01022117 chr1:201258280 PKP1 0.34 5.17 0.42 9.18e-7 Panic disorder; TGCT cis rs7666738 0.753 rs28390295 chr4:99028497 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4925325 0.915 rs2427246 chr20:60517047 T/C cg12751644 chr20:60527061 NA -0.52 -7.13 -0.54 7.26e-11 Obesity-related traits; TGCT cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg12667521 chr19:29218732 NA 0.53 5.63 0.45 1.16e-7 Methadone dose in opioid dependence; TGCT cis rs523522 0.962 rs7471 chr12:120941215 T/C cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs10504229 0.775 rs72650876 chr8:58161638 G/A cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9549367 0.789 rs2287247 chr13:113889212 A/G cg00898013 chr13:113819073 PROZ -0.4 -4.92 -0.4 2.7e-6 Platelet distribution width; TGCT cis rs4930561 0.714 rs7122250 chr11:67946472 T/C cg04465784 chr11:67976953 SUV420H1 -0.38 -5.47 -0.44 2.37e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs41308713 0.786 rs8116471 chr20:37034694 A/C cg09132763 chr20:37064059 LOC388796;SNORA71D 1.26 5.95 0.47 2.53e-8 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs916888 0.821 rs415430 chr17:44859144 C/T cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2033711 0.905 rs1077420 chr19:58968875 A/C cg13877915 chr19:58951672 ZNF132 0.85 9.82 0.66 3.48e-17 Uric acid clearance; TGCT trans rs1814175 0.817 rs12290508 chr11:49621037 C/T cg11707556 chr5:10655725 ANKRD33B -0.38 -7.79 -0.57 2.31e-12 Height; TGCT cis rs11711311 1.000 rs2603789 chr3:113470479 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg08219700 chr8:58056026 NA 0.39 4.74 0.39 5.64e-6 Developmental language disorder (linguistic errors); TGCT cis rs9322193 0.923 rs2297930 chr6:150039496 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs4699052 0.963 rs11943325 chr4:104178393 T/C cg16532752 chr4:104119610 CENPE -0.55 -4.97 -0.41 2.19e-6 Testicular germ cell tumor; TGCT cis rs3806843 0.868 rs2262574 chr5:140123635 G/T cg19875535 chr5:140030758 IK -0.34 -5.68 -0.45 8.89e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs1218582 0.772 rs4845400 chr1:154872523 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs6542838 0.611 rs13006398 chr2:99522323 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.08 -0.42 1.35e-6 Fear of minor pain; TGCT cis rs9911578 0.813 rs12452313 chr17:57129882 C/A cg05425664 chr17:57184151 TRIM37 0.67 6.14 0.48 1.04e-8 Intelligence (multi-trait analysis); TGCT cis rs2282802 0.635 rs270162 chr5:139539090 A/G cg01081189 chr5:139537190 NA -0.28 -5.16 -0.42 9.51e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.931 rs2989330 chr21:40716209 A/G cg17971929 chr21:40555470 PSMG1 0.88 7.1 0.54 8.62e-11 Cognitive function; TGCT cis rs10751667 0.666 rs7396509 chr11:956761 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs2243480 1.000 rs160634 chr7:65528664 C/T cg18252515 chr7:66147081 NA 1.03 7.24 0.55 4.11e-11 Diabetic kidney disease; TGCT cis rs2288278 0.601 rs60154639 chr17:46575562 G/A cg25032089 chr17:46643351 HOXB3 -0.42 -5.03 -0.41 1.68e-6 Hand grip strength; TGCT cis rs75686122 0.892 rs78235073 chr8:104647541 G/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs270601 0.683 rs81598 chr5:131587960 C/G cg24060327 chr5:131705240 SLC22A5 -0.59 -6.09 -0.48 1.32e-8 Acylcarnitine levels; TGCT cis rs6845621 0.754 rs7680497 chr4:18885282 T/C cg12196642 chr4:18937545 NA -0.24 -4.51 -0.38 1.5e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs10949662 1.000 rs11765189 chr7:157535977 A/G cg11757124 chr7:157526947 PTPRN2 -0.4 -4.65 -0.39 8.2e-6 Intelligence (multi-trait analysis); TGCT cis rs12643440 0.538 rs4698538 chr4:17150001 T/G cg22650099 chr4:17144496 NA -0.47 -4.84 -0.4 3.86e-6 Metabolite levels (Pyroglutamine); TGCT cis rs1499614 1.000 rs2659903 chr7:66180931 G/A cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs6540559 0.611 rs17015226 chr1:209970096 C/G cg23283495 chr1:209979779 IRF6 0.69 5.37 0.43 3.68e-7 Cleft lip with or without cleft palate; TGCT cis rs10771431 0.782 rs10771415 chr12:9358223 C/T cg08997352 chr12:9597637 DDX12 -0.3 -5.87 -0.47 3.72e-8 Breast size; TGCT cis rs36051895 0.632 rs7040922 chr9:5174829 A/G cg02405213 chr9:5042618 JAK2 0.79 11.03 0.7 3.99e-20 Pediatric autoimmune diseases; TGCT cis rs477895 0.838 rs35090903 chr11:64000598 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.83 6.91 0.53 2.2e-10 Mean platelet volume; TGCT cis rs9926296 0.581 rs6500457 chr16:89898764 C/G cg04287289 chr16:89883240 FANCA -0.67 -6.78 -0.52 4.35e-10 Vitiligo; TGCT cis rs589448 0.902 rs642786 chr12:69758462 T/C cg20891283 chr12:69753455 YEATS4 0.9 10.36 0.68 1.69e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs7809950 0.953 rs3094383 chr7:107143164 G/A cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs12257961 0.521 rs10796279 chr10:15375400 A/T cg10616319 chr10:15468812 NA -0.25 -4.56 -0.38 1.2e-5 Selective IgA deficiency; TGCT cis rs11122272 0.735 rs2790886 chr1:231529491 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT cis rs1552244 0.515 rs67626468 chr3:10161518 C/A cg00149659 chr3:10157352 C3orf10 1.1 6.89 0.53 2.45e-10 Alzheimer's disease; TGCT cis rs2243480 0.615 rs34363376 chr7:65939536 T/C cg07424592 chr7:64974309 NA 1.29 8.01 0.58 7.16e-13 Diabetic kidney disease; TGCT cis rs2836974 0.644 rs4818017 chr21:40690561 G/T cg17971929 chr21:40555470 PSMG1 -0.65 -5.56 -0.45 1.56e-7 Cognitive function; TGCT cis rs6840360 0.571 rs12648420 chr4:152543434 G/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs9436747 0.667 rs7519977 chr1:66033496 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.52 4.5 0.37 1.55e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs651907 0.557 rs13066768 chr3:101486920 A/T cg12386194 chr3:101231763 SENP7 -0.47 -4.59 -0.38 1.07e-5 Colorectal cancer; TGCT cis rs523522 0.962 rs12814055 chr12:120987391 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs10510102 0.872 rs12261371 chr10:123726201 A/C cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs1215050 0.791 rs1215054 chr4:98863009 T/G cg05340658 chr4:99064831 C4orf37 -0.47 -5.9 -0.47 3.18e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9427116 0.502 rs7531982 chr1:154596122 A/T cg17218026 chr1:154582156 ADAR 0.3 7.7 0.57 3.74e-12 Blood protein levels; TGCT cis rs10782582 0.609 rs1001160 chr1:76358591 A/C cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs35306767 0.953 rs7908138 chr10:962978 C/T cg26597838 chr10:835615 NA 0.66 9.01 0.63 3.04e-15 Eosinophil percentage of granulocytes; TGCT cis rs910187 0.641 rs6018327 chr20:45813126 C/T cg27589058 chr20:45804311 EYA2 -0.35 -7.55 -0.56 8.3e-12 Migraine; TGCT cis rs2645424 0.666 rs2272767 chr8:11711059 C/T cg18999641 chr8:11876646 NA 0.21 4.53 0.38 1.39e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs9650657 0.504 rs10109167 chr8:11033525 C/T cg21775007 chr8:11205619 TDH -0.49 -4.56 -0.38 1.19e-5 Neuroticism; TGCT cis rs62244186 1.000 rs62244186 chr3:44739783 G/A cg10263370 chr3:44754102 ZNF502 -0.45 -5.43 -0.44 2.89e-7 Depressive symptoms; TGCT cis rs9818758 0.556 rs116432667 chr3:48947589 C/T cg07636037 chr3:49044803 WDR6 -1.0 -4.98 -0.41 2.11e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs12477438 0.520 rs6542863 chr2:99725138 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs6988636 1.000 rs28600861 chr8:124189063 C/T cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs3820068 0.580 rs12746773 chr1:16001588 C/T cg05660106 chr1:15850417 CASP9 0.65 5.82 0.46 4.66e-8 Systolic blood pressure; TGCT cis rs4455778 0.580 rs4917034 chr7:49113788 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs1348850 0.632 rs1358328 chr2:178517532 G/A cg22681709 chr2:178499509 PDE11A -0.5 -6.0 -0.47 1.99e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs425277 0.606 rs2257182 chr1:2082566 C/T cg24578937 chr1:2090814 PRKCZ -0.25 -6.21 -0.49 7.4e-9 Height; TGCT cis rs174601 0.861 rs174584 chr11:61610750 G/A cg01500311 chr11:61656094 FADS3 -0.32 -5.42 -0.44 2.96e-7 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs9368481 0.729 rs10946881 chr6:26914611 C/T cg02458000 chr6:26745757 NA 0.61 5.41 0.44 3.1e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2115630 1.000 rs1030863 chr15:85282635 C/T cg11189052 chr15:85197271 WDR73 -0.63 -6.04 -0.48 1.67e-8 P wave terminal force; TGCT cis rs2075165 0.901 rs7522860 chr1:156275281 C/T cg16558208 chr1:156270281 VHLL 0.29 5.39 0.44 3.43e-7 Tonsillectomy; TGCT cis rs9549260 0.755 rs7333037 chr13:41215256 A/T cg21288729 chr13:41239152 FOXO1 0.97 10.09 0.67 7.57e-18 Red blood cell count; TGCT cis rs7267979 1.000 rs398036 chr20:25439850 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10791097 0.694 rs2236717 chr11:130739887 G/T cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4372836 0.729 rs10198789 chr2:28968811 C/T cg09522027 chr2:28974177 PPP1CB -0.63 -6.25 -0.49 6.12e-9 Body mass index; TGCT trans rs208520 0.690 rs207114 chr6:66791703 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.01 -10.93 -0.7 7.05e-20 Exhaled nitric oxide output; TGCT cis rs1008375 0.898 rs9998130 chr4:17593905 A/G cg16339924 chr4:17578868 LAP3 0.83 6.98 0.53 1.54e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs3780486 0.846 rs10813950 chr9:33127640 A/G cg20290983 chr6:43655470 MRPS18A -0.95 -7.85 -0.58 1.64e-12 IgG glycosylation; TGCT cis rs7781977 1.000 rs7781977 chr7:50346134 C/T cg01139861 chr7:50343298 IKZF1 0.54 5.67 0.45 9.61e-8 IgG glycosylation; TGCT cis rs138055607 1 rs138055607 chr10:75450901 C/G cg07699608 chr10:75541558 CHCHD1 0.7 4.84 0.4 3.79e-6 Initial pursuit acceleration; TGCT cis rs7267979 0.816 rs443009 chr20:25499817 A/G cg03522245 chr20:25566470 NINL -0.48 -4.87 -0.4 3.34e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854765 0.547 rs28537385 chr17:17902135 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.1 0.59 4.3e-13 Total body bone mineral density; TGCT cis rs2486012 1.000 rs17474535 chr1:44353084 A/G cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs2839186 0.814 rs2276257 chr21:47711229 A/G cg13732083 chr21:47605072 C21orf56 0.34 4.48 0.37 1.68e-5 Testicular germ cell tumor; TGCT cis rs514406 0.893 rs1242315 chr1:53417181 A/G cg08859206 chr1:53392774 SCP2 -0.41 -6.27 -0.49 5.57e-9 Monocyte count; TGCT cis rs2882877 0.513 rs10206897 chr2:190459793 A/T cg10752008 chr2:190445175 SLC40A1 -0.76 -6.87 -0.53 2.74e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs6582630 0.576 rs4882375 chr12:38371939 G/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs13108904 0.901 rs7673398 chr4:1300077 G/A cg00684032 chr4:1343700 KIAA1530 0.25 5.09 0.42 1.31e-6 Obesity-related traits; TGCT cis rs9943465 0.539 rs7068530 chr10:131990328 T/C cg00179795 chr10:131695114 EBF3 -0.36 -4.63 -0.38 9.19e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7267979 0.966 rs2263204 chr20:25377688 A/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs6490294 0.904 rs7304572 chr12:112525073 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.58 0.45 1.46e-7 Mean platelet volume; TGCT cis rs11252926 0.550 rs10795122 chr10:466830 C/T cg13477178 chr10:375248 DIP2C -0.24 -4.45 -0.37 1.88e-5 Psychosis in Alzheimer's disease; TGCT cis rs4478858 0.735 rs4949393 chr1:31851875 G/A cg07478791 chr1:31886160 SERINC2 -0.49 -4.73 -0.39 5.88e-6 Alcohol dependence; TGCT cis rs9611519 0.590 rs4821980 chr22:41415479 C/G cg06634786 chr22:41940651 POLR3H -0.49 -4.54 -0.38 1.33e-5 Neuroticism; TGCT cis rs6964587 0.692 rs12536220 chr7:91805595 T/G cg17063962 chr7:91808500 NA 0.74 6.94 0.53 1.93e-10 Breast cancer; TGCT trans rs877282 0.947 rs7475589 chr10:767479 C/G cg22713356 chr15:30763199 NA 1.17 9.64 0.65 9.24e-17 Uric acid levels; TGCT cis rs302972 0.826 rs303011 chr6:25080848 A/C cg18428180 chr6:24646492 KIAA0319 -1.03 -4.51 -0.38 1.49e-5 Creatinine levels in ischemic stroke; TGCT cis rs4819052 0.851 rs9974628 chr21:46672647 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9467773 1.000 rs6930120 chr6:26555484 A/G cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs9406161 chr6:8466144 G/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs1552244 1.000 rs17032283 chr3:10081545 C/G cg00149659 chr3:10157352 C3orf10 0.81 5.21 0.42 7.72e-7 Alzheimer's disease; TGCT cis rs1865760 1.000 rs9348698 chr6:25929689 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.18 0.49 8.63e-9 Height; TGCT cis rs2243480 1.000 rs6460274 chr7:65628484 T/A cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs7618915 0.547 rs13064064 chr3:52657002 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.07 0.48 1.47e-8 Bipolar disorder; TGCT cis rs1691799 0.867 rs1495497 chr12:66770020 A/T cg16791601 chr12:66731901 HELB -0.28 -5.88 -0.47 3.51e-8 White blood cell count (basophil); TGCT cis rs13191362 0.507 rs2846535 chr6:163034019 T/C cg06582575 chr6:163149167 PACRG;PARK2 -0.58 -5.72 -0.46 7.5e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs981844 1.000 rs2606329 chr4:154654643 A/C cg14289246 chr4:154710475 SFRP2 1.05 8.74 0.62 1.39e-14 Response to statins (LDL cholesterol change); TGCT cis rs68170813 0.559 rs12534676 chr7:106943640 G/A cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs10426930 0.752 rs10401934 chr19:5038715 C/T cg09001777 chr19:5851504 FUT3 0.21 4.46 0.37 1.78e-5 Monocyte percentage of white cells; TGCT cis rs1023500 0.551 rs4822076 chr22:42364057 C/T cg04692870 chr22:42525206 CYP2D6 0.32 5.06 0.41 1.47e-6 Schizophrenia; TGCT cis rs17711722 0.522 rs4642526 chr7:65216742 G/T cg07424592 chr7:64974309 NA -0.65 -6.34 -0.49 3.83e-9 Calcium levels; TGCT trans rs1973993 0.934 rs588660 chr1:96886604 G/A cg10631902 chr5:14652156 NA 0.35 7.94 0.58 1.04e-12 Weight; TGCT cis rs7647973 1.000 rs1009051 chr3:49521549 G/A cg07690219 chr3:49449608 TCTA;RHOA -0.53 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs514406 0.621 rs928452 chr1:53195926 G/C cg08859206 chr1:53392774 SCP2 0.34 4.82 0.4 4.1e-6 Monocyte count; TGCT cis rs4819052 0.679 rs2838859 chr21:46684517 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.64 6.19 0.49 8.26e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6693567 0.565 rs12731296 chr1:150411787 A/G cg09579323 chr1:150459698 TARS2 0.52 4.62 0.38 9.56e-6 Migraine; TGCT cis rs8177253 0.965 rs3811658 chr3:133476852 C/T cg08048268 chr3:133502702 NA -0.64 -9.25 -0.64 8.35e-16 Iron status biomarkers; TGCT cis rs12908161 0.920 rs35738019 chr15:85280210 T/C cg17173187 chr15:85201210 NMB 0.59 6.57 0.51 1.22e-9 Schizophrenia; TGCT cis rs9581857 0.685 rs9319371 chr13:28042564 A/G cg22138327 chr13:27999177 GTF3A 0.72 4.6 0.38 1.03e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs17711722 0.510 rs11767457 chr7:65290615 C/T cg07424592 chr7:64974309 NA -0.57 -5.55 -0.45 1.65e-7 Calcium levels; TGCT cis rs7100689 0.646 rs1340374 chr10:82129114 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs7085104 0.700 rs743572 chr10:104597152 A/G cg05855489 chr10:104503620 C10orf26 0.54 4.88 0.4 3.15e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs75229567 0.618 rs1882194 chr12:70215086 C/G cg10114359 chr12:70132523 RAB3IP -1.06 -5.93 -0.47 2.81e-8 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg08859206 chr1:53392774 SCP2 -0.45 -7.37 -0.55 2.16e-11 Monocyte count; TGCT cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg10263370 chr3:44754102 ZNF502 -0.39 -4.8 -0.4 4.41e-6 Depressive symptoms; TGCT cis rs17665859 0.844 rs17738513 chr8:446359 G/T cg17960703 chr8:356704 FBXO25 -1.4 -5.27 -0.43 5.9e-7 Bilirubin levels; TGCT cis rs916888 0.697 rs199516 chr17:44856485 C/T cg01570182 chr17:44337453 NA -1.01 -9.24 -0.64 8.71e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6460942 0.908 rs6956500 chr7:12232120 T/C cg06484146 chr7:12443880 VWDE -0.57 -4.74 -0.39 5.65e-6 Coronary artery disease; TGCT trans rs7618501 1.000 rs6775384 chr3:49853073 G/A cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.08e-30 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.877 rs10476596 chr5:93367074 C/T cg21475434 chr5:93447410 FAM172A -0.6 -4.62 -0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs981844 0.712 rs1037646 chr4:154738015 C/T cg14289246 chr4:154710475 SFRP2 -1.0 -9.32 -0.64 5.46e-16 Response to statins (LDL cholesterol change); TGCT cis rs3847687 0.966 rs3847689 chr12:131525534 T/G cg13586425 chr12:131519906 GPR133 -0.33 -5.26 -0.43 6.17e-7 Longevity; TGCT cis rs11209185 0.509 rs1926279 chr1:68450681 A/G cg22082780 chr1:68452167 NA 0.31 4.67 0.39 7.66e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs651907 0.514 rs12636046 chr3:101434448 T/G cg12386194 chr3:101231763 SENP7 0.51 4.9 0.4 2.89e-6 Colorectal cancer; TGCT cis rs13256369 0.951 rs13259955 chr8:8565885 C/G cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs2456568 0.803 rs10831142 chr11:93640781 A/G cg14065697 chr11:93583672 C11orf90 0.4 5.02 0.41 1.78e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6546537 0.868 rs62133967 chr2:69891708 G/C cg10773587 chr2:69614142 GFPT1 -0.82 -7.07 -0.54 1.01e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs62380364 0.692 rs61104616 chr5:88163771 G/A cg22951263 chr5:87985283 NA -0.52 -5.32 -0.43 4.77e-7 Intelligence (multi-trait analysis); TGCT cis rs617219 0.671 rs6414979 chr5:78548010 T/G cg23987322 chr5:78407566 BHMT 0.36 4.66 0.39 8.06e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1552244 0.882 rs13074282 chr3:10024699 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs4819052 0.851 rs2838864 chr21:46711474 A/T cg06618935 chr21:46677482 NA 0.36 5.76 0.46 6.18e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4788570 0.566 rs1804984 chr16:71481520 T/A cg06353428 chr16:71660113 MARVELD3 -1.32 -7.86 -0.58 1.6e-12 Intelligence (multi-trait analysis); TGCT cis rs4366490 0.848 rs2839987 chr11:62904137 T/G cg21002970 chr11:62369079 MTA2 0.87 4.67 0.39 7.78e-6 Conotruncal heart defects; TGCT cis rs514406 0.861 rs2065477 chr1:53250213 C/T cg08736216 chr1:53307985 ZYG11A -0.25 -4.92 -0.4 2.7e-6 Monocyte count; TGCT cis rs9359856 0.623 rs1179907 chr6:90324849 A/G cg13799429 chr6:90582589 CASP8AP2 -0.43 -4.69 -0.39 7.15e-6 Bipolar disorder; TGCT cis rs10883723 0.810 rs1884929 chr10:104275418 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs4713118 0.586 rs9468290 chr6:28087674 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Parkinson's disease; TGCT cis rs4819052 0.851 rs13052312 chr21:46662359 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.08 0.42 1.35e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg26818010 chr10:134567672 INPP5A -0.38 -5.21 -0.42 7.61e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2115630 0.936 rs8033459 chr15:85253258 C/T cg12863693 chr15:85201151 NMB -0.33 -4.51 -0.38 1.48e-5 P wave terminal force; TGCT cis rs9291683 0.588 rs4697705 chr4:10108127 G/A cg11266682 chr4:10021025 SLC2A9 -0.43 -5.16 -0.42 9.47e-7 Bone mineral density; TGCT cis rs9894429 0.966 rs10871499 chr17:79589006 G/A cg18240062 chr17:79603768 NPLOC4 0.67 6.85 0.52 3.11e-10 Eye color traits; TGCT cis rs7267979 0.873 rs6132822 chr20:25228695 C/T cg14121845 chr20:25566513 NINL 0.47 4.84 0.4 3.73e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs912057 0.526 rs1294400 chr6:6733421 A/G cg06612196 chr6:6737390 NA -0.46 -6.77 -0.52 4.57e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9443645 0.901 rs6937465 chr6:79570345 G/T cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs1865760 1.000 rs3799371 chr6:25912816 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.65 -6.36 -0.5 3.54e-9 Height; TGCT trans rs2688608 0.736 rs2227566 chr10:75673731 C/T cg13918328 chr10:52500089 ASAH2B 0.68 6.8 0.52 3.96e-10 Inflammatory bowel disease; TGCT cis rs11948739 0.539 rs1119863 chr5:130282399 T/G cg08523029 chr5:130500466 HINT1 0.6 4.9 0.4 2.88e-6 Pediatric bone mineral content (hip); TGCT cis rs911555 0.723 rs6575991 chr14:103908433 C/T cg23461800 chr14:103021989 NA -0.34 -4.5 -0.37 1.57e-5 Intelligence (multi-trait analysis); TGCT cis rs4141404 0.701 rs1985531 chr22:31566177 T/G cg02404636 chr22:31891804 SFI1 -0.31 -4.65 -0.39 8.51e-6 Paclitaxel-induced neuropathy; TGCT cis rs227584 0.663 rs2040810 chr17:42243771 C/T cg19774624 chr17:42201019 HDAC5 0.64 6.82 0.52 3.47e-10 Bone mineral density (hip);Bone mineral density; TGCT cis rs3776081 0.555 rs56293808 chr5:149538157 T/C cg18424208 chr5:149546337 CDX1 -0.25 -4.57 -0.38 1.16e-5 Blood protein levels; TGCT cis rs7568458 0.709 rs2028898 chr2:85777270 G/A cg02493740 chr2:85810744 VAMP5 -0.28 -5.26 -0.43 6.1e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs155076 1.000 rs2783107 chr13:21837532 C/A cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs10504229 0.953 rs57669205 chr8:58172253 T/C cg24829409 chr8:58192753 C8orf71 -0.57 -5.37 -0.43 3.74e-7 Developmental language disorder (linguistic errors); TGCT cis rs11065961 1 rs11065961 chr12:112023067 G/A cg10833066 chr12:111807467 FAM109A -0.37 -5.99 -0.47 2.15e-8 Platelet distribution width; TGCT cis rs1799949 0.965 rs799912 chr17:41257134 T/C cg05368731 chr17:41323189 NBR1 1.02 11.4 0.72 5.02e-21 Menopause (age at onset); TGCT cis rs12142240 0.698 rs17357635 chr1:46808668 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg24829409 chr8:58192753 C8orf71 -0.55 -5.2 -0.42 8.06e-7 Developmental language disorder (linguistic errors); TGCT cis rs9467773 0.595 rs4320356 chr6:26423560 C/T cg05738196 chr6:26577821 NA -0.52 -5.52 -0.44 1.88e-7 Intelligence (multi-trait analysis); TGCT cis rs826838 0.585 rs12296822 chr12:38625829 A/T cg26384229 chr12:38710491 ALG10B -0.54 -4.74 -0.39 5.87e-6 Heart rate; TGCT cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg15320075 chr8:145703422 NA -0.68 -6.82 -0.52 3.52e-10 Age at first birth; TGCT cis rs597539 0.652 rs579136 chr11:68637476 C/G cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12188164 1.000 rs72717412 chr5:429381 C/T cg21144161 chr5:423903 AHRR 0.26 4.93 0.4 2.59e-6 Cystic fibrosis severity; TGCT trans rs1908814 0.516 rs60176945 chr8:11796674 T/C cg15556689 chr8:8085844 FLJ10661 0.75 7.07 0.54 9.74e-11 Neuroticism; TGCT cis rs2115630 0.645 rs2292463 chr15:85175750 A/G cg11189052 chr15:85197271 WDR73 -0.75 -7.17 -0.54 5.89e-11 P wave terminal force; TGCT cis rs10504229 0.683 rs55637580 chr8:58135419 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs9999200 chr4:99030690 A/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7017914 0.967 rs13255735 chr8:71859739 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.29 -0.43 5.4e-7 Bone mineral density; TGCT cis rs1894292 0.527 rs1997333 chr4:74374425 G/A cg05868023 chr4:75230803 EREG 0.56 5.05 0.41 1.56e-6 Prostate cancer; TGCT cis rs597539 0.652 rs667989 chr11:68685776 T/A cg06028808 chr11:68637592 NA 0.52 6.67 0.51 7.43e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7264396 0.561 rs2050930 chr20:34579397 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.81 -0.4 4.29e-6 Total cholesterol levels; TGCT cis rs4851254 0.626 rs71413861 chr2:100673501 A/G cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs2440129 0.611 rs11571335 chr17:6904263 C/T cg03404566 chr17:6899310 ALOX12 0.45 5.12 0.42 1.14e-6 Tonsillectomy; TGCT cis rs7095607 0.606 rs4746737 chr10:69959779 T/C cg18986048 chr10:69913749 MYPN 0.59 6.2 0.49 7.86e-9 Lung function (FVC); TGCT cis rs854765 0.583 rs4925125 chr17:17794444 T/C cg09796270 chr17:17721594 SREBF1 -0.23 -4.69 -0.39 7.14e-6 Total body bone mineral density; TGCT cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg23172400 chr8:95962367 TP53INP1 -0.38 -6.49 -0.5 1.84e-9 Type 2 diabetes; TGCT cis rs2204008 0.555 rs7310307 chr12:38107497 G/T cg26384229 chr12:38710491 ALG10B 0.85 7.57 0.56 7.57e-12 Bladder cancer; TGCT cis rs6882076 1.000 rs6878680 chr5:156387137 G/C cg12943317 chr5:156479607 HAVCR1 -0.29 -5.27 -0.43 5.93e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs3806843 0.517 rs246031 chr5:140333107 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs10540 1.000 rs12419716 chr11:503385 C/G cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs1008375 0.897 rs6820164 chr4:17630115 G/A cg10189774 chr4:17578691 LAP3 0.64 5.47 0.44 2.42e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs56235845 0.964 rs4075958 chr5:176784512 A/G cg17509989 chr5:176798049 RGS14 -0.77 -12.25 -0.74 4.2e-23 Hemoglobin concentration;Hematocrit; TGCT cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs909674 0.690 rs5750825 chr22:39831278 A/G cg11247378 chr22:39784982 NA -0.73 -8.55 -0.61 3.78e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.61 -0.38 9.71e-6 Schizophrenia; TGCT cis rs9611519 0.929 rs73174660 chr22:41437304 T/C cg13695892 chr22:41940480 POLR3H -0.55 -4.9 -0.4 2.99e-6 Neuroticism; TGCT cis rs7552404 0.807 rs2066183 chr1:76153745 A/G cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2836974 0.526 rs418359 chr21:40536734 T/C cg06238570 chr21:40685208 BRWD1 -0.8 -9.1 -0.63 1.91e-15 Cognitive function; TGCT cis rs4242434 0.927 rs13264187 chr8:22506098 C/T cg03733263 chr8:22462867 KIAA1967 1.15 17.7 0.85 9.76e-36 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs4665809 0.590 rs62128455 chr2:26466530 G/A cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs7897654 0.571 rs12767543 chr10:104631663 G/A cg15744005 chr10:104629667 AS3MT -0.45 -4.52 -0.38 1.45e-5 Schizophrenia; TGCT cis rs2204008 0.806 rs7305409 chr12:38349133 G/A cg26384229 chr12:38710491 ALG10B 0.83 7.25 0.55 4e-11 Bladder cancer; TGCT cis rs4478858 0.735 rs10914344 chr1:31769025 T/C cg07478791 chr1:31886160 SERINC2 -0.49 -4.92 -0.4 2.73e-6 Alcohol dependence; TGCT cis rs10779751 0.922 rs11121708 chr1:11307253 G/C cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg15242686 chr22:24348715 GSTTP1 0.43 5.95 0.47 2.54e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17376456 0.569 rs10076965 chr5:93094972 G/A cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs916888 0.779 rs430685 chr17:44859148 T/C cg15921436 chr17:44337874 NA -0.51 -6.96 -0.53 1.77e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9308731 0.644 rs1054873 chr2:111876148 G/A cg04202892 chr2:111875749 ACOXL 0.54 6.22 0.49 6.95e-9 Chronic lymphocytic leukemia; TGCT cis rs9807841 0.670 rs8099926 chr19:10778647 A/G cg17848348 chr19:10766748 ILF3 -0.4 -4.58 -0.38 1.12e-5 Inflammatory skin disease; TGCT cis rs597539 0.652 rs660614 chr11:68659488 G/A cg04772025 chr11:68637568 NA 0.6 6.69 0.52 6.8e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7639513 0.767 rs2348201 chr3:12711696 A/G cg23032965 chr3:12705835 RAF1 0.78 8.62 0.61 2.61e-14 Itch intensity from mosquito bite; TGCT cis rs875971 0.862 rs1860469 chr7:66106875 A/G cg11764359 chr7:65958608 NA -0.55 -4.98 -0.41 2.1e-6 Aortic root size; TGCT cis rs7829975 0.774 rs13259216 chr8:8673601 A/C cg15556689 chr8:8085844 FLJ10661 0.67 6.08 0.48 1.38e-8 Mood instability; TGCT cis rs7666738 0.830 rs28451001 chr4:98924544 T/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7119 0.651 rs12904200 chr15:77845902 C/G cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs8017423 0.935 rs10147186 chr14:90779879 G/C cg04374321 chr14:90722782 PSMC1 0.74 7.09 0.54 8.75e-11 Mortality in heart failure; TGCT cis rs9650657 0.572 rs11250098 chr8:10818607 A/G cg21775007 chr8:11205619 TDH -0.53 -5.0 -0.41 1.93e-6 Neuroticism; TGCT cis rs17152411 1.000 rs7092008 chr10:126638226 G/A cg07906193 chr10:126599966 NA 0.41 5.11 0.42 1.18e-6 Height; TGCT cis rs4906332 0.966 rs7401563 chr14:103964425 G/A cg26031613 chr14:104095156 KLC1 -0.51 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs4253772 0.591 rs6008538 chr22:46685963 G/A cg24881330 chr22:46731750 TRMU 0.96 6.38 0.5 3.18e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs7618915 0.531 rs77146033 chr3:52701501 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.93 0.47 2.8e-8 Bipolar disorder; TGCT trans rs57221529 0.709 rs72703090 chr5:598314 C/T cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Lung disease severity in cystic fibrosis; TGCT cis rs2115630 1.000 rs10220733 chr15:85280864 G/A cg11189052 chr15:85197271 WDR73 -0.63 -6.04 -0.48 1.67e-8 P wave terminal force; TGCT cis rs1799949 1.000 rs4793229 chr17:41418334 C/T cg10047753 chr17:41438598 NA -0.94 -9.23 -0.64 9.06e-16 Menopause (age at onset); TGCT cis rs9393692 0.905 rs4412192 chr6:26290377 A/G cg00631329 chr6:26305371 NA 0.41 6.09 0.48 1.34e-8 Educational attainment; TGCT cis rs6964587 0.967 rs12531966 chr7:91765840 A/G cg22709100 chr7:91322751 NA 0.29 4.58 0.38 1.13e-5 Breast cancer; TGCT cis rs56104184 0.830 rs28556985 chr19:49351149 C/T cg15549821 chr19:49342101 PLEKHA4 -0.81 -9.48 -0.65 2.33e-16 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg21482265 chr2:113992762 PAX8;LOC440839;LOC654433 0.44 6.28 0.49 5.28e-9 Lymphocyte counts; TGCT cis rs7568458 0.846 rs6705839 chr2:85761279 A/T cg17127132 chr2:85788382 GGCX 0.56 5.39 0.44 3.47e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs782590 0.967 rs1975487 chr2:55809054 A/G cg03859395 chr2:55845619 SMEK2 0.91 11.13 0.71 2.26e-20 Metabolic syndrome; TGCT cis rs7666738 0.830 rs12233741 chr4:98950296 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.966 rs2286773 chr4:17616214 C/A cg16339924 chr4:17578868 LAP3 0.68 5.6 0.45 1.33e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs9929218 0.508 rs6499194 chr16:68744100 T/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.62 8.1 0.59 4.5e-13 Colorectal cancer; TGCT cis rs2885056 0.800 rs8105074 chr19:10708692 A/G cg04833646 chr19:10679720 CDKN2D 0.96 9.21 0.64 1.01e-15 Red cell distribution width; TGCT cis rs9807989 0.765 rs6704565 chr2:102967431 G/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 5.35 0.43 4.14e-7 Height; TGCT cis rs2692947 0.644 rs1030864 chr2:96822373 A/G cg22654517 chr2:96458247 NA 0.23 4.91 0.4 2.8e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs617219 0.659 rs13182512 chr5:78573790 A/T cg09550809 chr5:78407562 BHMT -0.37 -5.24 -0.43 6.65e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs780096 0.546 rs8179225 chr2:27737181 A/G cg12000995 chr2:27665139 KRTCAP3 -0.37 -4.44 -0.37 1.98e-5 Total body bone mineral density; TGCT cis rs514406 0.570 rs1332776 chr1:53189816 C/T cg24675658 chr1:53192096 ZYG11B -0.88 -12.64 -0.75 4.86e-24 Monocyte count; TGCT cis rs6121246 0.522 rs6088736 chr20:30195166 C/G cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs7524258 0.868 rs4243824 chr1:7289777 G/A cg07173049 chr1:7289937 CAMTA1 0.29 4.91 0.4 2.81e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7666738 0.830 rs11947578 chr4:98930462 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs681343 1.000 rs679574 chr19:49206108 C/G cg13540341 chr19:49222985 MAMSTR -0.33 -4.48 -0.37 1.69e-5 Lung adenocarcinoma;Primary sclerosing cholangitis;Childhood ear infection; TGCT cis rs12478296 0.901 rs58906257 chr2:243028248 T/C cg06360820 chr2:242988706 NA -0.58 -4.62 -0.38 9.32e-6 Obesity-related traits; TGCT cis rs9902453 1.000 rs56280226 chr17:28429575 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.74 6.57 0.51 1.22e-9 Coffee consumption (cups per day); TGCT cis rs17401966 0.838 rs912963 chr1:10348042 C/T cg19773385 chr1:10388646 KIF1B -0.21 -4.79 -0.4 4.59e-6 Hepatocellular carcinoma; TGCT cis rs9291683 0.588 rs34501273 chr4:9996996 C/T cg00071950 chr4:10020882 SLC2A9 0.74 9.16 0.64 1.33e-15 Bone mineral density; TGCT cis rs17253792 0.822 rs77415412 chr14:56154146 A/G cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg11494091 chr17:61959527 GH2 0.42 7.46 0.56 1.29e-11 Height; TGCT cis rs7100689 0.622 rs10887798 chr10:82131613 G/A cg01528321 chr10:82214614 TSPAN14 0.78 7.61 0.56 5.85e-12 Post bronchodilator FEV1; TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg10263370 chr3:44754102 ZNF502 0.43 5.1 0.42 1.21e-6 Depressive symptoms; TGCT cis rs1552244 0.572 rs17032426 chr3:10167112 G/A cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs9682041 0.877 rs9682908 chr3:170072010 C/T cg11886554 chr3:170076028 SKIL 0.55 4.58 0.38 1.11e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.74 0.39 5.79e-6 Prudent dietary pattern; TGCT cis rs1577917 0.740 rs12212560 chr6:86342679 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.54 -4.87 -0.4 3.28e-6 Response to antipsychotic treatment; TGCT cis rs9790314 0.846 rs4560315 chr3:160982132 G/T cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs10255878 0.500 rs11975657 chr7:97040014 C/T cg01534613 chr7:96337050 SHFM1 0.29 4.44 0.37 1.97e-5 Adverse response to radiation therapy; TGCT cis rs3793683 0.556 rs2803989 chr10:134560596 C/T cg27286337 chr10:134555280 INPP5A 0.42 5.28 0.43 5.56e-7 Migraine; TGCT cis rs597539 0.652 rs513359 chr11:68669496 A/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.85 -8.21 -0.59 2.42e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9443645 0.901 rs9352670 chr6:79584433 A/G cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs1334894 1.000 rs113244441 chr6:35528690 C/A cg24281267 chr6:35479648 TULP1 -0.43 -4.47 -0.37 1.78e-5 Coronary artery disease; TGCT cis rs1552244 0.935 rs41520445 chr3:10153141 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 0.48 6.74 0.52 5.26e-10 Alzheimer's disease; TGCT cis rs4689388 0.889 rs13101355 chr4:6293446 T/C cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3812831 0.695 rs423237 chr13:114930955 C/T cg15513719 chr13:114904418 NA 0.38 4.65 0.39 8.31e-6 Schizophrenia; TGCT cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg02725872 chr8:58115012 NA -0.39 -4.83 -0.4 3.9e-6 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.503 rs5751156 chr22:42170025 A/G cg06481639 chr22:41940642 POLR3H 0.68 5.95 0.47 2.59e-8 Vitiligo; TGCT cis rs7772486 0.790 rs9497424 chr6:146225271 C/A cg23711669 chr6:146136114 FBXO30 -0.85 -9.77 -0.66 4.46e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9640161 0.830 rs13307276 chr7:150061525 T/C cg10018233 chr7:150070692 REPIN1 0.31 4.73 0.39 5.9e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs1552244 1.000 rs7622963 chr3:10139825 C/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs4819052 1.000 rs733739 chr21:46666210 A/G cg06618935 chr21:46677482 NA -0.37 -4.94 -0.41 2.5e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4455778 0.580 rs6952911 chr7:49092794 C/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs4555082 0.874 rs2816620 chr14:105732704 G/T cg01266790 chr14:105781312 PACS2 0.56 4.6 0.38 1.04e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs10254284 0.885 rs10276070 chr7:28150689 T/C cg23620719 chr7:28220237 JAZF1 -0.53 -4.69 -0.39 7.18e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs514406 0.861 rs6588443 chr1:53250650 G/A cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT trans rs1814175 0.817 rs10839318 chr11:49657511 G/C cg03929089 chr4:120376271 NA -0.74 -8.94 -0.63 4.49e-15 Height; TGCT cis rs4237845 0.788 rs6581157 chr12:58288793 C/T cg23860436 chr12:58378763 NA 0.37 5.31 0.43 4.9e-7 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.69 4.91 0.4 2.75e-6 Platelet count; TGCT cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg23205692 chr1:25664452 TMEM50A -0.47 -4.88 -0.4 3.21e-6 Erythrocyte sedimentation rate; TGCT cis rs7698623 0.850 rs4693892 chr4:88796983 T/G cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs1692580 0.870 rs262680 chr1:2167149 C/T cg24578937 chr1:2090814 PRKCZ 0.21 4.68 0.39 7.54e-6 Coronary artery disease; TGCT cis rs922182 0.569 rs7180050 chr15:64263784 G/A cg02919090 chr15:64263738 DAPK2 0.36 6.87 0.53 2.76e-10 Blood protein levels; TGCT cis rs10501293 0.746 rs7929831 chr11:43006825 G/A cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.2e-9 Cognitive performance; TGCT cis rs9388451 0.657 rs4895799 chr6:126052729 C/T cg05901451 chr6:126070800 HEY2 -0.92 -9.7 -0.66 6.85e-17 Brugada syndrome; TGCT cis rs344364 0.511 rs1742473 chr16:1953095 T/C cg26617929 chr16:1858877 NA -0.26 -4.66 -0.39 8.04e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9527 0.615 rs12248123 chr10:104735366 A/G cg15744005 chr10:104629667 AS3MT -0.47 -5.57 -0.45 1.47e-7 Arsenic metabolism; TGCT cis rs881375 1.000 rs7037140 chr9:123656327 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.34 0.43 4.31e-7 Rheumatoid arthritis; TGCT cis rs9942416 0.650 rs2640646 chr5:74977458 A/T cg19683494 chr5:74908142 NA -0.6 -6.37 -0.5 3.39e-9 Age-related disease endophenotypes; TGCT cis rs6121246 0.559 rs6087779 chr20:30370566 T/C cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Mean corpuscular hemoglobin; TGCT cis rs7208859 0.623 rs11657662 chr17:29076347 A/G cg13385521 chr17:29058706 SUZ12P -0.8 -4.85 -0.4 3.66e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10883723 0.810 rs2296586 chr10:104245575 C/T cg05855489 chr10:104503620 C10orf26 -0.55 -4.88 -0.4 3.21e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7172809 0.548 rs75329354 chr15:77668065 C/T cg22256960 chr15:77711686 NA -0.51 -4.79 -0.4 4.65e-6 Glucose homeostasis traits; TGCT cis rs2921036 0.545 rs4840975 chr8:8363258 C/T cg15556689 chr8:8085844 FLJ10661 -0.56 -4.98 -0.41 2.04e-6 Neuroticism; TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg11965913 chr1:205819406 PM20D1 0.51 7.2 0.54 5.16e-11 Menarche (age at onset); TGCT cis rs4862750 0.914 rs6814259 chr4:187872337 T/C cg11301795 chr4:187892539 NA -0.34 -5.03 -0.41 1.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11696501 0.694 rs6130870 chr20:44263263 T/C cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT cis rs6840360 0.573 rs7692939 chr4:152258455 C/T cg17479576 chr4:152424074 FAM160A1 -0.42 -4.51 -0.38 1.5e-5 Intelligence (multi-trait analysis); TGCT cis rs1030877 0.557 rs2278501 chr2:105979506 C/T cg02079111 chr2:105885981 TGFBRAP1 -0.17 -5.28 -0.43 5.65e-7 Obesity-related traits; TGCT trans rs731174 0.592 rs6699887 chr1:38192604 G/A cg19725343 chr19:51830960 IGLON5 -0.63 -7.19 -0.54 5.35e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs12210905 0.688 rs72841376 chr6:27456321 G/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7714584 1.000 rs7714415 chr5:150270292 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs769267 0.965 rs2965191 chr19:19453521 T/G cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs526231 0.853 rs35802 chr5:102607585 A/T cg05225461 chr5:102596755 C5orf30 0.23 4.65 0.39 8.39e-6 Primary biliary cholangitis; TGCT cis rs7614311 0.594 rs2280162 chr3:63997491 C/T cg22134162 chr3:63841271 THOC7 -0.31 -4.49 -0.37 1.59e-5 Lung function (FVC);Lung function (FEV1); TGCT cis rs7666738 0.830 rs6831588 chr4:98977356 T/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs17767294 0.708 rs72845896 chr6:27697645 C/G cg08851530 chr6:28072375 NA 1.56 7.38 0.55 1.95e-11 Parkinson's disease; TGCT cis rs2033711 0.783 rs11671113 chr19:58958087 C/T cg13877915 chr19:58951672 ZNF132 0.91 11.5 0.72 2.79e-21 Uric acid clearance; TGCT cis rs7772486 0.686 rs857875 chr6:145980033 T/G cg23711669 chr6:146136114 FBXO30 -0.83 -9.29 -0.64 6.68e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7582180 0.602 rs7585582 chr2:100998030 G/C cg08017756 chr2:100939284 LONRF2 -0.31 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.791 rs7377018 chr4:99034962 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs614226 0.516 rs1794748 chr12:120953758 A/G cg01236616 chr12:121019343 POP5 1.26 13.2 0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT cis rs13242816 0.881 rs17138706 chr7:116109019 A/G cg02799643 chr7:116139180 CAV2 -0.48 -5.45 -0.44 2.56e-7 P wave duration; TGCT cis rs8038465 0.571 rs7176654 chr15:73999006 C/T cg15420318 chr15:73925796 NPTN -0.59 -5.81 -0.46 4.97e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467773 1.000 rs1321481 chr6:26538210 A/T cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg22166914 chr1:53195759 ZYG11B 0.37 6.41 0.5 2.77e-9 Monocyte count; TGCT cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg17054783 chr10:134559939 INPP5A 0.26 5.21 0.42 7.76e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7100689 0.577 rs7901663 chr10:82153488 C/G cg01528321 chr10:82214614 TSPAN14 0.68 6.8 0.52 4e-10 Post bronchodilator FEV1; TGCT cis rs7811142 0.779 rs77370288 chr7:99947897 A/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs7208859 0.623 rs9916725 chr17:29107471 A/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2204008 0.744 rs11519905 chr12:38222959 G/A cg13010199 chr12:38710504 ALG10B 0.62 4.87 0.4 3.26e-6 Bladder cancer; TGCT cis rs2116941 1.000 rs8104426 chr19:10338676 G/T cg01850179 chr19:10340795 S1PR2 0.76 10.43 0.68 1.14e-18 Pulse pressure; TGCT cis rs1371867 0.513 rs1542812 chr8:101207064 G/A cg00191853 chr8:101177733 SPAG1 0.29 6.45 0.5 2.26e-9 Atrioventricular conduction; TGCT cis rs79349575 0.783 rs4294857 chr17:46983391 G/A cg26022315 chr17:47021804 SNF8 0.48 4.82 0.4 4.06e-6 Type 2 diabetes; TGCT cis rs11711311 0.868 rs13091621 chr3:113481977 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT cis rs2742234 0.504 rs7093409 chr10:43740067 A/G cg02780029 chr10:43622663 RET 0.26 4.91 0.4 2.84e-6 Hirschsprung disease; TGCT cis rs2456568 0.771 rs8181530 chr11:93638678 G/A cg14065697 chr11:93583672 C11orf90 -0.38 -4.74 -0.39 5.65e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2346177 0.576 rs1530621 chr2:46688688 T/C cg26688816 chr2:46740690 ATP6V1E2 -0.41 -4.49 -0.37 1.62e-5 HDL cholesterol; TGCT cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg00343986 chr7:65444356 GUSB 0.26 6.14 0.48 1.05e-8 Aortic root size; TGCT cis rs35160687 0.862 rs13024964 chr2:86511868 G/A cg03171300 chr2:86307199 POLR1A 0.32 5.39 0.44 3.35e-7 Night sleep phenotypes; TGCT cis rs11785400 0.793 rs4567014 chr8:143737690 G/C cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs10736390 1.000 rs11206402 chr1:55104317 G/C cg01517571 chr1:55089959 ACOT11;FAM151A -0.42 -8.1 -0.59 4.34e-13 Survival in pancreatic cancer; TGCT cis rs6121246 0.529 rs6060296 chr20:30198480 T/C cg13852791 chr20:30311386 BCL2L1 0.7 4.68 0.39 7.29e-6 Mean corpuscular hemoglobin; TGCT cis rs4294134 0.608 rs11763242 chr7:135242973 T/G cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs7826238 0.566 rs2945886 chr8:8148270 C/G cg15462221 chr8:8086144 FLJ10661 -0.53 -4.71 -0.39 6.46e-6 Systolic blood pressure; TGCT cis rs35306767 0.904 rs10904584 chr10:983747 A/T cg20503657 chr10:835505 NA 0.58 7.98 0.58 8.43e-13 Eosinophil percentage of granulocytes; TGCT cis rs4494114 1.000 rs10890491 chr1:39354602 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.1e-9 Blood protein levels; TGCT cis rs6088590 1.000 rs6119516 chr20:33328024 C/T cg06115741 chr20:33292138 TP53INP2 0.66 5.38 0.44 3.54e-7 Coronary artery disease; TGCT cis rs10984561 0.881 rs12235333 chr9:122247927 A/G cg14242995 chr9:122249943 NA 0.75 6.41 0.5 2.7e-9 Pulmonary function decline; TGCT cis rs7666738 0.791 rs34790496 chr4:98930516 C/T cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.8e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs9291683 0.530 rs4697698 chr4:9942577 C/T cg00071950 chr4:10020882 SLC2A9 0.68 8.55 0.61 3.91e-14 Bone mineral density; TGCT cis rs801193 1.000 rs6975195 chr7:66124774 T/A cg18876405 chr7:65276391 NA -0.34 -5.19 -0.42 8.37e-7 Aortic root size; TGCT cis rs9372498 0.536 rs62424199 chr6:118827252 G/A cg21191810 chr6:118973309 C6orf204 -0.36 -4.77 -0.39 5.1e-6 Diastolic blood pressure; TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg14159672 chr1:205819179 PM20D1 0.62 7.38 0.55 1.99e-11 Menarche (age at onset); TGCT cis rs7208859 0.623 rs3752021 chr17:29111043 G/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs861020 0.606 rs629224 chr1:210005071 C/T cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg24829409 chr8:58192753 C8orf71 -0.55 -5.17 -0.42 9.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6484504 0.576 rs208072 chr11:31141288 A/G cg26647111 chr11:31128758 NA 0.33 4.69 0.39 7.09e-6 Red blood cell count; TGCT cis rs3806843 0.832 rs2531360 chr5:140116664 G/A cg19875535 chr5:140030758 IK -0.34 -5.75 -0.46 6.6e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs1775715 0.737 rs11817598 chr10:32206259 A/G cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6089584 0.888 rs6142927 chr20:60605848 A/G cg13665807 chr20:60559372 TAF4 -0.48 -5.1 -0.42 1.22e-6 Body mass index; TGCT cis rs2637266 0.745 rs241 chr10:78444456 G/T cg18941641 chr10:78392320 NA 0.37 4.5 0.37 1.57e-5 Pulmonary function; TGCT cis rs12477438 0.520 rs6542870 chr2:99796638 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs68170813 0.559 rs7794598 chr7:106826381 C/T cg02696742 chr7:106810147 HBP1 -0.73 -6.54 -0.51 1.41e-9 Coronary artery disease; TGCT cis rs6089829 0.888 rs4809268 chr20:61675249 C/G cg08045932 chr20:61659980 NA 0.5 8.69 0.62 1.75e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs1843834 0.755 rs10194591 chr2:225574276 T/A cg22455342 chr2:225449267 CUL3 0.66 6.28 0.49 5.25e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs3784262 0.935 rs4646636 chr15:58251034 A/G cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.63 -0.57 5.26e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs13108904 0.967 rs4642180 chr4:1278914 T/C cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.41 2.55e-6 Obesity-related traits; TGCT cis rs611744 0.967 rs630492 chr8:109215368 C/T cg21045802 chr8:109455806 TTC35 -0.52 -4.79 -0.4 4.63e-6 Dupuytren's disease; TGCT trans rs1005277 0.505 rs7917943 chr10:38195811 T/A cg17830980 chr10:43048298 ZNF37B 0.74 8.59 0.61 3.11e-14 Extrinsic epigenetic age acceleration; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg14893161 chr1:205819251 PM20D1 0.57 8.2 0.59 2.5e-13 Menarche (age at onset); TGCT cis rs13191362 1.000 rs13200329 chr6:163004418 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2455799 0.613 rs13096622 chr3:15837656 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.19e-6 Mean platelet volume; TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg27535305 chr1:53392650 SCP2 -0.27 -5.47 -0.44 2.39e-7 Monocyte count; TGCT cis rs4700695 0.719 rs27588 chr5:65459360 C/A cg21114390 chr5:65439923 SFRS12 -0.84 -7.33 -0.55 2.58e-11 Facial morphology (factor 19); TGCT cis rs35160687 0.901 rs35762338 chr2:86513553 G/A cg12542933 chr2:85804724 VAMP8 0.4 4.79 0.39 4.75e-6 Night sleep phenotypes; TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg18402987 chr7:1209562 NA 0.38 4.86 0.4 3.51e-6 Longevity;Endometriosis; TGCT cis rs10791323 0.569 rs10791328 chr11:133713730 A/G cg15485101 chr11:133734466 NA 0.42 5.45 0.44 2.62e-7 Childhood ear infection; TGCT cis rs7043114 0.525 rs7864630 chr9:95267560 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.37 -0.43 3.72e-7 Height; TGCT cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs651907 0.535 rs11707250 chr3:101509371 A/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.51 -4.86 -0.4 3.51e-6 Colorectal cancer; TGCT cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg20203395 chr5:56204925 C5orf35 -0.61 -5.35 -0.43 4.05e-7 Initial pursuit acceleration; TGCT cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2439831 1.000 rs1814538 chr15:43759774 C/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.78 -5.91 -0.47 3.04e-8 Lung cancer in ever smokers; TGCT cis rs79349575 0.783 rs62075839 chr17:46996434 G/C cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT trans rs208520 0.690 rs12192710 chr6:66718137 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs1057239 0.510 rs3766694 chr1:175143207 T/C cg14847009 chr1:175162515 KIAA0040 -0.35 -5.16 -0.42 9.35e-7 Diastolic blood pressure; TGCT cis rs6725041 0.819 rs4350692 chr2:213090220 T/C cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs6920364 1 rs6920364 chr6:167376466 G/C cg25258033 chr6:167368657 RNASET2 -0.2 -4.82 -0.4 4.19e-6 Lung cancer; TGCT cis rs17221829 0.617 rs11018677 chr11:89362820 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.67 -0.39 7.58e-6 Anxiety in major depressive disorder; TGCT cis rs28785552 0.931 rs10424385 chr19:53239133 C/G cg04754360 chr19:53238445 ZNF611 -0.71 -5.64 -0.45 1.11e-7 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs2549003 1.000 rs6894655 chr5:131818649 T/C cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs933688 0.639 rs332530 chr5:90789810 G/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 7.6 0.56 6.19e-12 Smoking behavior; TGCT cis rs12477438 0.520 rs4850897 chr2:99768419 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs9467773 0.595 rs7767847 chr6:26597893 A/T cg11502198 chr6:26597334 ABT1 0.54 4.96 0.41 2.31e-6 Intelligence (multi-trait analysis); TGCT cis rs9583531 0.689 rs9521905 chr13:111352600 G/A cg24331049 chr13:111365604 ING1 -0.88 -8.19 -0.59 2.68e-13 Coronary artery disease; TGCT cis rs9914988 0.943 rs9894335 chr17:27138483 C/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT trans rs4332037 0.906 rs62442903 chr7:1953416 G/A cg25206134 chr2:45395956 NA 1.06 9.01 0.63 3.03e-15 Bipolar disorder; TGCT cis rs9682041 0.866 rs6444926 chr3:170133235 T/C cg11886554 chr3:170076028 SKIL 0.87 6.38 0.5 3.18e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs4919694 0.572 rs12243903 chr10:104906992 T/C cg04362960 chr10:104952993 NT5C2 0.97 6.81 0.52 3.82e-10 Arsenic metabolism; TGCT cis rs4824093 0.610 rs56810176 chr22:50303149 G/C cg20569369 chr22:51173646 NA 0.29 4.56 0.38 1.19e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs28735056 0.660 rs12454454 chr18:77674634 C/T cg20368463 chr18:77673604 PQLC1 -0.55 -6.67 -0.51 7.65e-10 Schizophrenia; TGCT cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.88 0.47 3.59e-8 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.601 rs9379224 chr6:8538413 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs1552244 0.572 rs68013239 chr3:10165711 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.12 0.42 1.11e-6 Alzheimer's disease; TGCT cis rs7582180 0.764 rs11691684 chr2:100921776 T/A cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT trans rs7819412 0.775 rs2898257 chr8:10935368 A/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.07 -0.54 1.01e-10 Triglycerides; TGCT cis rs910316 0.967 rs1071989 chr14:75564659 G/T cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs7226408 0.948 rs72883595 chr18:34392790 T/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs9611565 0.512 rs6002474 chr22:42168181 A/G cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs9902453 1.000 rs9912741 chr17:28359511 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs9326248 1.000 rs585849 chr11:117069061 A/G cg26566898 chr11:117069891 TAGLN 0.35 4.95 0.41 2.32e-6 Blood protein levels; TGCT cis rs8077889 1.000 rs59044152 chr17:41888747 A/G cg26893861 chr17:41843967 DUSP3 1.1 12.5 0.75 1.08e-23 Triglycerides; TGCT cis rs7829975 0.806 rs2428 chr8:8641145 C/T cg08975724 chr8:8085496 FLJ10661 0.53 4.58 0.38 1.12e-5 Mood instability; TGCT cis rs2997447 0.739 rs3008224 chr1:26389647 G/A cg19633962 chr1:26362018 EXTL1 -0.68 -4.62 -0.38 9.47e-6 QRS complex (12-leadsum); TGCT cis rs7666738 0.830 rs6839203 chr4:98839814 C/G cg18180107 chr4:99064573 C4orf37 0.56 5.17 0.42 9.04e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6908034 0.769 rs6916589 chr6:19761363 T/G cg02682789 chr6:19804855 NA 0.81 4.64 0.38 8.61e-6 Endometriosis;Deep ovarian and/or rectovaginal disease with dense adhesions; TGCT cis rs6087771 0.642 rs6060411 chr20:30222139 T/C cg18721089 chr20:30220636 NA -0.42 -5.19 -0.42 8.31e-7 Subcortical brain region volumes;Putamen volume; TGCT cis rs8072100 0.935 rs12150231 chr17:45717091 G/A cg08085267 chr17:45401833 C17orf57 0.47 5.13 0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs76473307 1.000 rs79820260 chr20:57420268 G/A cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs10782582 0.586 rs1796813 chr1:76400403 G/A cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.34e-6 Daytime sleep phenotypes; TGCT cis rs9858542 1.000 rs9836291 chr3:49697459 G/A cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs10782582 0.609 rs1159215 chr1:76317869 A/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.51 4.53 0.38 1.34e-5 Daytime sleep phenotypes; TGCT cis rs1005277 0.522 rs7072977 chr10:37940440 C/A cg25427524 chr10:38739819 LOC399744 -0.35 -7.04 -0.53 1.18e-10 Extrinsic epigenetic age acceleration; TGCT cis rs17767294 0.708 rs72851182 chr6:28106699 G/T cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs7809950 0.954 rs2520247 chr7:107143946 A/T cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs10782582 0.609 rs5745545 chr1:76377356 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.55 4.72 0.39 6.24e-6 Daytime sleep phenotypes; TGCT cis rs2562456 0.720 rs6511250 chr19:21656046 C/T cg25650185 chr19:21324782 ZNF431 0.56 4.85 0.4 3.68e-6 Pain; TGCT cis rs3087591 0.960 rs12603885 chr17:29466722 C/T cg24425628 chr17:29625626 OMG;NF1 0.49 7.65 0.57 4.83e-12 Hip circumference; TGCT trans rs11764590 0.715 rs55770986 chr7:2087823 T/C cg25206134 chr2:45395956 NA 0.97 6.72 0.52 5.86e-10 Neuroticism; TGCT cis rs9393692 0.846 rs9366651 chr6:26336696 G/T cg00631329 chr6:26305371 NA -0.38 -5.6 -0.45 1.31e-7 Educational attainment; TGCT cis rs9993613 0.875 rs1518487 chr4:73466458 G/C cg15102770 chr4:73434591 ADAMTS3 0.51 4.8 0.4 4.47e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs611744 0.870 rs638905 chr8:109203406 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT trans rs114540395 0.858 rs77209663 chr10:103300166 G/A cg10198749 chr1:39920707 MACF1 0.55 7.05 0.53 1.11e-10 Schizophrenia; TGCT cis rs7829975 0.626 rs332040 chr8:8730488 G/A cg15556689 chr8:8085844 FLJ10661 0.67 6.22 0.49 6.82e-9 Mood instability; TGCT cis rs4788570 0.615 rs7193549 chr16:71649416 T/C cg06353428 chr16:71660113 MARVELD3 1.55 12.96 0.76 8.29e-25 Intelligence (multi-trait analysis); TGCT cis rs4595586 0.545 rs12811619 chr12:39392196 T/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7824557 0.614 rs7816606 chr8:11205602 T/C cg21775007 chr8:11205619 TDH 0.71 6.77 0.52 4.57e-10 Retinal vascular caliber; TGCT cis rs208520 0.690 rs851459 chr6:66813989 A/G cg07460842 chr6:66804631 NA -0.93 -9.66 -0.66 8.29e-17 Exhaled nitric oxide output; TGCT cis rs7264396 0.790 rs6058288 chr20:34228680 A/G cg04508476 chr20:34239394 CPNE1;RBM12 0.28 4.68 0.39 7.38e-6 Total cholesterol levels; TGCT cis rs8013055 0.796 rs8021330 chr14:106002352 C/A cg23356831 chr14:105996513 TMEM121 0.35 5.71 0.46 7.75e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs1448094 0.556 rs11611968 chr12:86168022 G/A cg02569458 chr12:86230093 RASSF9 0.38 4.49 0.37 1.61e-5 Major depressive disorder; TGCT trans rs916888 0.821 rs199514 chr17:44856881 G/A cg22433210 chr17:43662623 NA -1.01 -7.25 -0.55 3.91e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12950390 0.853 rs55745341 chr17:45855778 G/C cg06532163 chr17:45867833 NA 0.33 5.2 0.42 8.03e-7 IgG glycosylation; TGCT cis rs858239 0.601 rs10239760 chr7:23149950 C/T cg05602783 chr7:23145260 KLHL7 -0.72 -6.17 -0.48 8.95e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs9467773 1.000 rs9467787 chr6:26556769 G/T cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs17345786 0.861 rs11711808 chr3:101235101 T/C cg11279151 chr3:101281821 RG9MTD1 -0.42 -8.68 -0.61 1.85e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs7178424 0.516 rs12595300 chr15:62324519 T/C cg00456672 chr15:62358751 C2CD4A -0.29 -4.46 -0.37 1.84e-5 Height; TGCT cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2243480 0.522 rs431168 chr7:65511604 G/T cg18252515 chr7:66147081 NA -1.13 -6.09 -0.48 1.29e-8 Diabetic kidney disease; TGCT cis rs3796352 0.527 rs11716506 chr3:52944328 C/T cg07884673 chr3:53033167 SFMBT1 0.46 4.68 0.39 7.39e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7772486 0.754 rs864148 chr6:145976675 T/C cg13319975 chr6:146136371 FBXO30 0.57 5.19 0.42 8.17e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9952991 1.000 rs9952991 chr18:12780464 G/A cg23544223 chr18:12777786 NA 0.62 5.85 0.47 4.05e-8 Inflammatory skin disease; TGCT cis rs10504229 0.728 rs17215851 chr8:58154160 A/C cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs12497850 0.644 rs11928552 chr3:48739883 T/C cg16497277 chr3:49208875 KLHDC8B -0.49 -4.53 -0.38 1.36e-5 Parkinson's disease; TGCT cis rs7246657 0.943 rs7255407 chr19:37933936 G/A cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs13217239 0.646 rs10946891 chr6:26973215 T/C cg15659132 chr6:26577336 NA 0.55 5.55 0.45 1.62e-7 Schizophrenia; TGCT cis rs6733011 0.582 rs2280256 chr2:99449174 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.92 -0.4 2.66e-6 Bipolar disorder; TGCT cis rs17539620 0.624 rs62432743 chr6:154836214 T/G cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs31872 0.520 rs246053 chr5:140326290 T/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Visceral adipose tissue adjusted for BMI; TGCT cis rs9399135 0.967 rs4895436 chr6:135295001 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs2677744 1.000 rs1266489 chr15:91458485 G/A cg22288577 chr15:91498497 RCCD1 0.47 4.83 0.4 3.95e-6 Attention deficit hyperactivity disorder; TGCT cis rs7020830 0.823 rs7019699 chr9:37125081 C/A cg14294708 chr9:37120828 ZCCHC7 1.31 20.37 0.88 2.24e-41 Schizophrenia; TGCT cis rs6088580 0.601 rs6059872 chr20:33082775 C/A cg08999081 chr20:33150536 PIGU 0.29 5.57 0.45 1.54e-7 Glomerular filtration rate (creatinine); TGCT cis rs13191362 1.000 rs66529337 chr6:163005662 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1552244 1.000 rs9879080 chr3:10084224 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9549260 0.609 rs9315781 chr13:41264053 T/C cg21288729 chr13:41239152 FOXO1 0.9 8.44 0.6 7.07e-14 Red blood cell count; TGCT cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs8031584 0.678 rs3122 chr15:31170290 A/T cg08704250 chr15:31115839 NA 0.45 6.16 0.48 9.25e-9 Huntington's disease progression; TGCT cis rs6500602 0.627 rs11639998 chr16:4527109 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.28 0.49 5.19e-9 Schizophrenia; TGCT cis rs2070488 0.965 rs35091896 chr3:38443320 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.96 10.52 0.69 6.73e-19 Electrocardiographic conduction measures; TGCT cis rs875971 1.000 rs7792762 chr7:66004138 T/C cg11764359 chr7:65958608 NA 0.59 5.32 0.43 4.66e-7 Aortic root size; TGCT cis rs1949733 1.000 rs2631740 chr4:8484106 C/A cg13073564 chr4:8508604 NA 0.48 5.13 0.42 1.08e-6 Response to antineoplastic agents; TGCT cis rs2439831 0.867 rs28415933 chr15:43635800 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs9913156 0.789 rs55999196 chr17:4600655 A/G cg19197139 chr17:4613644 ARRB2 0.83 7.74 0.57 3.03e-12 Lymphocyte counts; TGCT cis rs1218582 0.682 rs12144978 chr1:154850445 G/A cg16680214 chr1:154839983 KCNN3 -0.42 -8.81 -0.62 9.12e-15 Prostate cancer; TGCT cis rs2204008 0.811 rs2139752 chr12:38370398 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.39 0.55 1.91e-11 Bladder cancer; TGCT cis rs8180040 0.800 rs11920354 chr3:47262246 C/A cg27129171 chr3:47204927 SETD2 -0.67 -7.84 -0.58 1.77e-12 Colorectal cancer; TGCT cis rs3087591 1.000 rs8068801 chr17:29570587 G/T cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.48 -0.56 1.18e-11 Hip circumference; TGCT cis rs1018836 0.608 rs1015994 chr8:91465011 T/C cg16814680 chr8:91681699 NA -0.72 -7.55 -0.56 8.16e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs939658 0.967 rs11629665 chr15:79457133 C/T cg17916960 chr15:79447300 NA 0.49 7.91 0.58 1.21e-12 Refractive error; TGCT cis rs79057730 0.599 rs34411410 chr7:811721 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.74 5.59 0.45 1.36e-7 Initial pursuit acceleration; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.99 0.41 2.03e-6 Prudent dietary pattern; TGCT cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs9899728 0.520 rs12936866 chr17:73052050 A/G cg27626185 chr17:73056755 KCTD2 -0.92 -8.01 -0.58 7.17e-13 Alzheimer's disease or small vessel stroke; TGCT cis rs9796 0.516 rs28473405 chr15:41293170 C/T cg26219294 chr15:41245916 CHAC1 0.38 4.64 0.38 8.83e-6 Menopause (age at onset); TGCT cis rs17473412 0.963 rs76431217 chr5:122697458 G/A cg15125798 chr5:122621645 NA -0.56 -5.02 -0.41 1.75e-6 Total body bone mineral density; TGCT cis rs1552244 0.572 rs67227131 chr3:10172744 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -5.43 -0.44 2.9e-7 Alzheimer's disease; TGCT cis rs7647973 0.626 rs9830730 chr3:49675875 G/C cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs1670533 1.000 rs13119276 chr4:1051574 T/C cg27284194 chr4:1044797 NA 0.68 5.8 0.46 5.11e-8 Recombination rate (females); TGCT cis rs4273100 0.688 rs12938803 chr17:19204432 A/C cg03910582 chr17:19030146 GRAPL -0.46 -5.17 -0.42 9.23e-7 Schizophrenia; TGCT cis rs7120118 0.517 rs3758671 chr11:47273089 G/C cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.16e-7 HDL cholesterol; TGCT cis rs78456975 0.574 rs13412980 chr2:1545231 C/A cg01028140 chr2:1542097 TPO -0.39 -5.51 -0.44 1.97e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs55962025 0.842 rs362272 chr4:3234980 C/T cg06533319 chr4:3265114 C4orf44 0.23 4.54 0.38 1.31e-5 Parental longevity (mother's age at death); TGCT cis rs35146811 0.807 rs6953441 chr7:99617067 G/A cg13334819 chr7:99746414 C7orf59 -0.82 -7.38 -0.55 2.05e-11 Coronary artery disease; TGCT cis rs1474256 0.630 rs79015977 chr15:79450147 G/A cg17916960 chr15:79447300 NA 0.39 5.38 0.44 3.56e-7 Bronchopulmonary dysplasia; TGCT cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg24829409 chr8:58192753 C8orf71 -0.6 -5.18 -0.42 8.6e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs4323111 chr4:98952276 A/G cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.8e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6701037 0.782 rs12760073 chr1:175139295 G/T cg00321850 chr1:175162397 KIAA0040 -0.41 -5.51 -0.44 1.95e-7 Alcohol dependence; TGCT cis rs68170813 0.559 rs3801963 chr7:106898036 C/T cg02696742 chr7:106810147 HBP1 -0.66 -5.51 -0.44 1.94e-7 Coronary artery disease; TGCT cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg20203395 chr5:56204925 C5orf35 -0.56 -4.67 -0.39 7.83e-6 Initial pursuit acceleration; TGCT cis rs4730250 0.707 rs80095766 chr7:106901394 G/T cg02696742 chr7:106810147 HBP1 -0.66 -5.51 -0.44 1.94e-7 Osteoarthritis; TGCT cis rs9921192 1.000 rs9921192 chr16:4349111 T/C cg00021532 chr16:4324280 TFAP4 0.75 7.96 0.58 9.23e-13 Prostate-specific antigen levels; TGCT cis rs3806843 0.900 rs2563287 chr5:140124786 C/T cg19875535 chr5:140030758 IK 0.35 5.81 0.46 4.92e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2153535 0.580 rs6597326 chr6:8482019 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs4824093 0.610 rs60036544 chr22:50264019 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.48 4.97 0.41 2.17e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7258465 1.000 rs10413237 chr19:18548249 A/C cg06462663 chr19:18546047 ISYNA1 0.2 4.56 0.38 1.21e-5 Breast cancer; TGCT cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg05738196 chr6:26577821 NA 0.87 11.3 0.71 8.47e-21 Intelligence (multi-trait analysis); TGCT cis rs1150668 0.796 rs2531825 chr6:28349264 C/T cg19488431 chr6:28601329 NA 0.2 4.63 0.38 9.19e-6 Pubertal anthropometrics; TGCT cis rs7647973 0.626 rs35129566 chr3:49866584 T/G cg05785598 chr3:49045655 WDR6 -0.42 -5.32 -0.43 4.71e-7 Menarche (age at onset); TGCT cis rs10858047 0.824 rs222502 chr1:115165472 T/A cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs1218582 0.772 rs10908445 chr1:154849590 A/G cg06221963 chr1:154839813 KCNN3 0.72 13.42 0.77 6.35e-26 Prostate cancer; TGCT cis rs6952808 0.531 rs3800922 chr7:2184505 A/G cg22963979 chr7:1858916 MAD1L1 -0.38 -6.04 -0.48 1.64e-8 Bipolar disorder and schizophrenia; TGCT cis rs36051895 0.632 rs10114315 chr9:5125741 G/A cg02405213 chr9:5042618 JAK2 -0.75 -10.16 -0.67 5.11e-18 Pediatric autoimmune diseases; TGCT cis rs9807989 0.839 rs4851565 chr2:102971481 C/A cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs2742417 1.000 rs1877934 chr3:45753295 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9296092 0.538 rs62405948 chr6:33522753 A/C cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7428 0.527 rs1053560 chr2:85546192 C/T cg03728395 chr2:85555865 TGOLN2 -0.32 -5.51 -0.44 2.02e-7 Ear protrusion; TGCT cis rs7208859 0.623 rs7208088 chr17:29143667 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg08736216 chr1:53307985 ZYG11A -0.26 -5.01 -0.41 1.83e-6 Monocyte count; TGCT cis rs11118844 0.843 rs7518806 chr1:221915633 T/A cg04222084 chr1:221915650 DUSP10 -0.88 -5.95 -0.47 2.59e-8 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs7772486 0.875 rs7739371 chr6:146424353 C/G cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs4253772 0.591 rs11704614 chr22:46691936 A/G cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs8177179 0.967 rs4078166 chr3:133435979 C/A cg16262614 chr3:133464971 TF 0.35 4.73 0.39 6.04e-6 Iron status biomarkers (transferrin levels); TGCT cis rs523522 0.962 rs651627 chr12:121009198 C/T cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs7085104 0.700 rs7096183 chr10:104609466 T/C cg15744005 chr10:104629667 AS3MT -0.45 -5.8 -0.46 5.2e-8 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs17331151 0.505 rs71299610 chr3:52641703 T/G cg07884673 chr3:53033167 SFMBT1 0.75 5.59 0.45 1.35e-7 Immune reponse to smallpox (secreted IL-2); TGCT trans rs7726839 0.540 rs72707016 chr5:665148 A/G cg25482853 chr8:67687455 SGK3 1.19 10.53 0.69 6.56e-19 Obesity-related traits; TGCT cis rs7246657 1.000 rs10426297 chr19:37798373 A/G cg18154014 chr19:37997991 ZNF793 0.81 5.56 0.45 1.61e-7 Coronary artery calcification; TGCT cis rs71281886 1 rs71281886 chr3:48352568 C/CA cg11946769 chr3:48343235 NME6 0.82 7.03 0.53 1.23e-10 Breast cancer; TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg17345569 chr6:42928274 GNMT -0.47 -4.81 -0.4 4.25e-6 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs11992162 0.621 rs9774603 chr8:11777406 C/T cg15556689 chr8:8085844 FLJ10661 -0.79 -6.77 -0.52 4.69e-10 Monocyte count; TGCT cis rs9858542 0.537 rs9818758 chr3:49382925 G/A cg00383909 chr3:49044727 WDR6 0.7 4.75 0.39 5.48e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6940638 0.744 rs858964 chr6:27142614 C/G cg26531700 chr6:26746687 NA 0.63 5.73 0.46 7.17e-8 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.846 rs1788199 chr8:101292854 A/G cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs12477438 0.520 rs6741772 chr2:99738961 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.16 0.84 1.49e-34 Chronic sinus infection; TGCT cis rs1862618 0.525 rs2662021 chr5:56261691 C/T cg12311346 chr5:56204834 C5orf35 0.79 6.87 0.53 2.76e-10 Initial pursuit acceleration; TGCT cis rs67072384 1.000 rs2886367 chr11:72455034 C/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs11122272 0.668 rs2808616 chr1:231554993 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.66 6.37 0.5 3.33e-9 Hemoglobin concentration; TGCT cis rs77972916 0.611 rs11693190 chr2:43602415 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.2 -0.49 7.52e-9 Granulocyte percentage of myeloid white cells; TGCT cis rs7937682 0.824 rs539524 chr11:111477325 A/G cg09085632 chr11:111637200 PPP2R1B -1.04 -11.09 -0.71 2.89e-20 Primary sclerosing cholangitis; TGCT cis rs981844 0.712 rs897610 chr4:154755439 C/A cg14289246 chr4:154710475 SFRP2 -0.96 -8.97 -0.63 3.91e-15 Response to statins (LDL cholesterol change); TGCT cis rs6582630 0.555 rs11182193 chr12:38474090 C/G cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs6754311 0.550 rs1438307 chr2:136499166 A/C cg07169764 chr2:136633963 MCM6 0.65 6.03 0.48 1.76e-8 Mosquito bite size; TGCT cis rs2820315 1.000 rs2250377 chr1:201860626 A/G cg12730843 chr1:201915899 LMOD1 0.27 4.73 0.39 5.98e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs6964587 0.900 rs4279 chr7:91764128 C/A cg17063962 chr7:91808500 NA 0.92 9.77 0.66 4.5e-17 Breast cancer; TGCT cis rs200810 0.664 rs35997403 chr6:98030207 T/C cg16511841 chr6:97730490 C6orf167;MIR548H3 -0.65 -4.44 -0.37 1.94e-5 Body mass index; TGCT cis rs4788570 0.697 rs6499540 chr16:71822250 A/C cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs4665809 1.000 rs4665308 chr2:26330514 C/A cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs2243480 0.901 rs778687 chr7:65835819 G/A cg07424592 chr7:64974309 NA 1.27 7.28 0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs10986311 0.862 rs2416924 chr9:127108146 A/T cg14243010 chr9:127117328 LOC100129034;PSMB7 0.2 4.79 0.4 4.57e-6 Vitiligo; TGCT cis rs79349575 0.721 rs4794004 chr17:47038471 C/T cg07967210 chr17:47022446 SNF8 0.44 5.94 0.47 2.68e-8 Type 2 diabetes; TGCT cis rs10972341 0.904 rs10972352 chr9:35151320 A/T cg00812861 chr9:35114699 KIAA1539 0.33 5.06 0.41 1.44e-6 Weight; TGCT cis rs3008870 0.959 rs56707923 chr1:67388016 T/C cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs10791323 0.569 rs2156679 chr11:133742304 C/T cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg03188948 chr7:1209495 NA 0.65 5.39 0.44 3.36e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs61867294 0.597 rs2050801 chr10:106694346 G/A cg08000847 chr10:105880925 C10orf78 0.49 4.43 0.37 2.01e-5 Schizophrenia; TGCT cis rs611744 0.967 rs650968 chr8:109211055 C/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs9894429 0.789 rs7502346 chr17:79603741 T/C cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs28374715 0.783 rs11635269 chr15:41570710 A/G cg18705301 chr15:41695430 NDUFAF1 -0.82 -12.81 -0.75 1.87e-24 Ulcerative colitis; TGCT cis rs12484776 0.685 rs1807579 chr22:40528220 T/C cg07138101 chr22:40742427 ADSL 0.62 4.82 0.4 4.09e-6 Uterine fibroids; TGCT cis rs806215 1.000 rs806219 chr7:127240094 A/C cg00893242 chr7:127291580 SND1 0.43 4.5 0.37 1.54e-5 Type 2 diabetes; TGCT cis rs155076 1.000 rs484365 chr13:21845944 G/T cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs738144 0.542 rs4303811 chr22:39157755 A/G cg06022373 chr22:39101656 GTPBP1 -0.77 -5.14 -0.42 1.05e-6 IgG glycosylation; TGCT cis rs10504229 0.593 rs16921626 chr8:58040359 C/T cg08280861 chr8:58055591 NA 0.4 5.57 0.45 1.49e-7 Developmental language disorder (linguistic errors); TGCT cis rs4642101 0.824 rs9820977 chr3:12842932 G/A cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs12136530 0.593 rs9287046 chr1:19736395 C/G cg24875000 chr1:19041556 PAX7 -0.25 -4.47 -0.37 1.72e-5 Lead levels in blood; TGCT cis rs6952808 0.723 rs60432611 chr7:2029629 G/C cg04267008 chr7:1944627 MAD1L1 -0.41 -5.45 -0.44 2.65e-7 Bipolar disorder and schizophrenia; TGCT cis rs79349575 0.783 rs318095 chr17:46974734 T/C cg26022315 chr17:47021804 SNF8 0.48 4.65 0.39 8.39e-6 Type 2 diabetes; TGCT cis rs11690462 0.794 rs2384364 chr2:26541427 C/G cg15315096 chr2:27193331 MAPRE3 0.52 4.46 0.37 1.8e-5 Coronary artery disease; TGCT cis rs8084125 0.832 rs62105172 chr18:74946703 C/T cg05528293 chr18:74961138 GALR1 0.48 4.8 0.4 4.45e-6 Obesity-related traits; TGCT cis rs9911578 1.000 rs12938772 chr17:56776320 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs10789285 0.681 rs2249230 chr1:69701497 A/T ch.1.69469992R chr1:69697404 NA 0.3 4.46 0.37 1.82e-5 Psoriasis; TGCT cis rs12134245 0.776 rs625525 chr1:91997593 C/T cg25838465 chr1:92012736 NA -0.41 -7.0 -0.53 1.44e-10 Breast cancer; TGCT cis rs6964587 0.934 rs6465344 chr7:91640273 G/A cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs727505 1.000 rs28523990 chr7:124436139 C/T cg23710748 chr7:124431027 NA -0.27 -4.53 -0.38 1.4e-5 Lewy body disease; TGCT cis rs66573146 1.000 rs59683609 chr4:6964910 C/G cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs12477438 0.765 rs62154638 chr2:99639584 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs1997103 1.000 rs1965556 chr7:55403584 C/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6121246 0.522 rs6088736 chr20:30195166 C/G cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT trans rs7819412 0.668 rs2409714 chr8:11010118 A/G cg15556689 chr8:8085844 FLJ10661 -0.73 -6.79 -0.52 4.14e-10 Triglycerides; TGCT cis rs12477438 0.520 rs2516829 chr2:99773201 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.03 12.17 0.74 6.51e-23 Chronic sinus infection; TGCT cis rs5769765 1.000 rs5769764 chr22:50270784 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs13256369 1.000 rs4840352 chr8:8573508 A/G cg18904891 chr8:8559673 CLDN23 0.62 5.67 0.45 9.47e-8 Obesity-related traits; TGCT cis rs9906944 0.545 rs11079850 chr17:47092252 G/T cg07075026 chr17:47091521 IGF2BP1 -0.44 -4.6 -0.38 1.02e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs1801251 1.000 rs3816334 chr2:233708806 A/G cg25237894 chr2:233734115 C2orf82 -0.33 -5.94 -0.47 2.71e-8 Coronary artery disease; TGCT cis rs2120019 1.000 rs7162900 chr15:75368017 T/C cg09165964 chr15:75287851 SCAMP5 -1.09 -8.86 -0.62 7.08e-15 Blood trace element (Zn levels); TGCT cis rs2242194 0.844 rs11264295 chr1:154987526 C/T cg24348479 chr1:155007323 DCST1;DCST2 0.27 5.73 0.46 7.17e-8 Schizophrenia; TGCT cis rs926938 0.505 rs360629 chr1:115414733 A/G cg12756093 chr1:115239321 AMPD1 0.41 6.44 0.5 2.37e-9 Autism; TGCT cis rs2070488 1.000 rs7373805 chr3:38455439 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 9.06e-17 Electrocardiographic conduction measures; TGCT cis rs2361718 0.522 rs11867921 chr17:78121170 G/T cg27614120 chr17:77386099 HRNBP3 0.26 4.56 0.38 1.22e-5 Yeast infection; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg10108389 chr3:44770937 ZNF501 -0.49 -4.9 -0.4 2.92e-6 Depressive symptoms; TGCT cis rs9611519 0.929 rs9611465 chr22:41426139 G/A cg13695892 chr22:41940480 POLR3H -0.53 -4.62 -0.38 9.54e-6 Neuroticism; TGCT cis rs981844 0.775 rs17371261 chr4:154738479 G/T cg14289246 chr4:154710475 SFRP2 -1.0 -8.8 -0.62 9.95e-15 Response to statins (LDL cholesterol change); TGCT cis rs6815814 0.851 rs9715769 chr4:38774489 A/C cg02016764 chr4:38805732 TLR1 -0.35 -5.67 -0.45 9.56e-8 Breast cancer; TGCT cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg03264133 chr6:25882463 NA -0.88 -8.54 -0.61 4.08e-14 Intelligence (multi-trait analysis); TGCT cis rs877282 1.000 rs11253369 chr10:773610 C/G cg17470449 chr10:769945 NA 0.31 5.23 0.43 6.96e-7 Uric acid levels; TGCT cis rs916888 0.821 rs199509 chr17:44858728 G/A cg01570182 chr17:44337453 NA -1.01 -9.1 -0.63 1.83e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs200895692 1 rs200895692 chr1:43421956 CGCCTGTAATCCCAG/C cg12656391 chr1:43425156 SLC2A1 -0.55 -5.43 -0.44 2.92e-7 Monocyte count; TGCT cis rs7582180 0.663 rs6542930 chr2:100944383 T/A cg08017756 chr2:100939284 LONRF2 -0.3 -5.01 -0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs7584330 0.518 rs78856668 chr2:238438055 A/C cg14458575 chr2:238380390 NA 0.43 4.52 0.38 1.44e-5 Prostate cancer; TGCT cis rs367943 0.933 rs451453 chr5:112808970 G/C cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs9788333 0.788 rs35007728 chr13:21893221 G/C cg04632378 chr13:21900426 NA 0.41 4.55 0.38 1.27e-5 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9611565 0.729 rs169362 chr22:41827589 G/C cg17554472 chr22:41940697 POLR3H 0.46 5.0 0.41 1.89e-6 Vitiligo; TGCT cis rs9929218 0.861 rs4783667 chr16:68752878 C/A cg01251360 chr16:68772225 CDH1 0.3 4.83 0.4 3.92e-6 Colorectal cancer; TGCT trans rs7618501 0.633 rs2624843 chr3:49997963 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.4 0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs835154 0.900 rs835153 chr5:14877474 A/G cg14843632 chr5:14870594 ANKH 0.44 6.52 0.5 1.64e-9 Blood metabolite levels; TGCT trans rs10203711 0.966 rs4293520 chr2:239567184 A/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs796364 0.616 rs2689762 chr2:200687204 G/T cg17644776 chr2:200775616 C2orf69 0.35 4.96 0.41 2.29e-6 Schizophrenia; TGCT cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs736408 0.648 rs3774355 chr3:52817778 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.53 0.51 1.55e-9 Bipolar disorder; TGCT cis rs13392177 0.637 rs61041183 chr2:219056380 G/A cg00012203 chr2:219082015 ARPC2 0.79 8.34 0.6 1.23e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg20999797 chr1:1681921 NA 0.19 4.83 0.4 4.01e-6 Body mass index; TGCT cis rs881375 0.631 rs10739577 chr9:123668854 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.92e-7 Rheumatoid arthritis; TGCT cis rs2920503 1.000 rs2920503 chr3:12324230 C/T cg04748988 chr3:12329223 PPARG 0.63 5.46 0.44 2.46e-7 LDL cholesterol; TGCT cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs4975709 0.610 rs1531994 chr5:1859297 T/C cg15595755 chr5:1867978 NA 0.45 5.13 0.42 1.08e-6 Cardiovascular disease risk factors; TGCT cis rs7120118 0.517 rs2290149 chr11:47345916 T/C cg13308137 chr11:47528955 CUGBP1 0.33 5.04 0.41 1.63e-6 HDL cholesterol; TGCT cis rs6840360 0.642 rs2709819 chr4:152383832 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.31 -0.49 4.44e-9 Intelligence (multi-trait analysis); TGCT cis rs4383453 0.539 rs12633849 chr3:123102862 T/C cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT trans rs1005277 0.602 rs1831315 chr10:38473353 T/C cg27523141 chr10:43048294 ZNF37B 0.72 8.28 0.6 1.71e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7179456 0.545 rs585192 chr15:59052210 T/C cg05156742 chr15:59063176 FAM63B 0.5 4.8 0.4 4.45e-6 Asperger disorder; TGCT cis rs9535307 0.769 rs9535306 chr13:50290817 A/G cg08779649 chr13:50194554 NA 0.41 4.81 0.4 4.35e-6 Obesity-related traits; TGCT cis rs6586163 0.872 rs1926201 chr10:90746360 G/C cg03111039 chr10:90751583 FAS;ACTA2 -0.37 -4.59 -0.38 1.06e-5 Chronic lymphocytic leukemia; TGCT cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT trans rs2624839 0.629 rs2526397 chr3:50187790 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.76 -6.73 -0.52 5.5e-10 Intelligence (multi-trait analysis); TGCT cis rs858239 0.539 rs3950345 chr7:23191114 T/C cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7666738 0.800 rs28427190 chr4:98989106 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs2061690 chr1:154919080 C/T cg09359103 chr1:154839909 KCNN3 -0.65 -12.28 -0.74 3.6e-23 Prostate cancer; TGCT cis rs9916302 0.904 rs13341996 chr17:37536862 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs4253772 0.515 rs6007891 chr22:46756833 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.73 4.85 0.4 3.56e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs3947 1.000 rs2645425 chr8:11701278 G/A cg02840367 chr8:11660030 FDFT1 0.91 6.7 0.52 6.58e-10 Blood protein levels; TGCT cis rs34526934 0.566 rs35563571 chr2:177044459 T/G cg14324370 chr2:177042789 NA -0.91 -8.6 -0.61 2.9e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs35160687 0.736 rs6746198 chr2:86542113 A/G cg03171300 chr2:86307199 POLR1A -0.27 -4.73 -0.39 6.06e-6 Night sleep phenotypes; TGCT cis rs5769765 0.955 rs9616366 chr22:50301178 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.21 0.42 7.51e-7 Schizophrenia; TGCT cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg22800045 chr5:56110881 MAP3K1 0.53 4.49 0.37 1.64e-5 Initial pursuit acceleration; TGCT cis rs600231 0.719 rs7114809 chr11:65251444 A/G cg17120908 chr11:65337727 SSSCA1 -0.56 -5.21 -0.42 7.77e-7 Bone mineral density; TGCT cis rs28595532 0.920 rs115472708 chr4:119773407 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs17376456 0.825 rs67328989 chr5:93243133 T/A cg25358565 chr5:93447407 FAM172A 1.01 7.9 0.58 1.29e-12 Diabetic retinopathy; TGCT cis rs919433 0.617 rs700638 chr2:198588950 A/C cg00792783 chr2:198669748 PLCL1 0.53 4.69 0.39 6.95e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs12497850 0.931 rs11705888 chr3:48817289 T/C cg07636037 chr3:49044803 WDR6 0.95 10.74 0.69 2e-19 Parkinson's disease; TGCT cis rs73198271 1.000 rs11776513 chr8:8609057 T/C ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs4851254 0.660 rs35869550 chr2:100684578 T/A cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs12711979 0.765 rs897069 chr2:3818947 C/T cg17052675 chr2:3827356 NA 0.4 7.89 0.58 1.34e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs12048904 0.964 rs8888 chr1:101338324 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 4.58 0.38 1.12e-5 Multiple sclerosis; TGCT cis rs28595532 0.920 rs116634064 chr4:119736514 C/T cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs10032931 0.717 rs970689 chr4:96460537 A/G cg17031751 chr4:96469067 UNC5C -0.36 -4.48 -0.37 1.7e-5 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs12541335 0.692 rs2290274 chr8:22214374 C/T cg02463440 chr8:22132932 PIWIL2 0.27 5.21 0.42 7.6e-7 Hypertriglyceridemia; TGCT cis rs1005277 0.557 rs2983338 chr10:38550734 C/T cg25427524 chr10:38739819 LOC399744 -0.41 -8.55 -0.61 3.9e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2594989 0.943 rs11128550 chr3:11466828 C/T cg00170343 chr3:11313890 ATG7 -0.65 -4.75 -0.39 5.51e-6 Circulating chemerin levels; TGCT cis rs7605378 0.528 rs281780 chr2:200756331 G/C cg17644776 chr2:200775616 C2orf69 0.34 7.46 0.56 1.31e-11 Osteoporosis; TGCT cis rs13217239 0.646 rs10946898 chr6:27003884 T/C cg15659132 chr6:26577336 NA 0.54 5.44 0.44 2.78e-7 Schizophrenia; TGCT cis rs7027203 0.576 rs7865043 chr9:96549004 G/T cg14598338 chr9:96623480 NA 0.52 7.51 0.56 1.01e-11 DNA methylation (variation); TGCT cis rs2806561 0.765 rs641032 chr1:23513980 C/T cg12483005 chr1:23474871 LUZP1 -0.37 -4.67 -0.39 7.86e-6 Height; TGCT cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg13695892 chr22:41940480 POLR3H 0.88 8.63 0.61 2.45e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs904251 0.600 rs11756241 chr6:37445101 C/T cg01843034 chr6:37503916 NA -0.47 -6.03 -0.48 1.78e-8 Cognitive performance; TGCT trans rs7726839 0.507 rs72703100 chr5:614291 C/T cg25482853 chr8:67687455 SGK3 1.23 9.86 0.66 2.81e-17 Obesity-related traits; TGCT cis rs7772486 0.603 rs2223411 chr6:146028767 T/C cg23711669 chr6:146136114 FBXO30 -0.73 -6.84 -0.52 3.19e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3785574 0.962 rs2247435 chr17:61892862 G/A cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.91 0.4 2.83e-6 Height; TGCT cis rs832540 0.866 rs832579 chr5:56164943 A/G cg12311346 chr5:56204834 C5orf35 -0.46 -5.0 -0.41 1.87e-6 Coronary artery disease; TGCT cis rs950027 0.549 rs11070452 chr15:45594836 C/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.39 -0.55 1.86e-11 Response to fenofibrate (adiponectin levels); TGCT cis rs902774 0.530 rs11834907 chr12:53350985 C/T cg03404339 chr12:52639319 KRT7 0.41 4.46 0.37 1.85e-5 Prostate cancer; TGCT cis rs12887734 0.524 rs12588797 chr14:104300020 C/T cg26031613 chr14:104095156 KLC1 0.72 6.2 0.49 7.61e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs9583531 0.600 rs4773241 chr13:111363021 A/G cg24331049 chr13:111365604 ING1 0.76 7.31 0.55 2.95e-11 Coronary artery disease; TGCT cis rs4665809 1.000 rs12471809 chr2:26307140 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs2657888 0.529 rs12316930 chr12:56885816 C/G cg23002907 chr12:56915593 RBMS2 -0.37 -4.66 -0.39 7.9e-6 Adiponectin levels; TGCT cis rs875971 0.862 rs6944374 chr7:65686929 C/G cg11764359 chr7:65958608 NA -0.52 -4.75 -0.39 5.45e-6 Aortic root size; TGCT cis rs2463822 0.925 rs1881535 chr11:62121623 C/T cg06239285 chr11:62104954 ASRGL1 0.92 6.76 0.52 4.71e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6099314 0.920 rs6014857 chr20:55453688 A/G cg18918007 chr20:54975754 CSTF1 0.27 4.52 0.38 1.44e-5 Chronic obstructive pulmonary disease (moderate to severe); TGCT cis rs6088590 1.000 rs6058111 chr20:33310999 T/C cg06115741 chr20:33292138 TP53INP2 0.66 5.39 0.44 3.37e-7 Coronary artery disease; TGCT cis rs751728 0.687 rs4711355 chr6:33759906 G/T cg13859433 chr6:33739653 LEMD2 -0.33 -5.78 -0.46 5.71e-8 Crohn's disease; TGCT cis rs9926296 0.744 rs164747 chr16:89708680 T/G cg26513180 chr16:89883248 FANCA -0.61 -5.76 -0.46 6.13e-8 Vitiligo; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs9527 0.615 rs11191485 chr10:104729816 G/C cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs11761231 1.000 rs4348414 chr7:131369298 C/T cg08326674 chr7:132266446 PLXNA4 0.23 4.57 0.38 1.14e-5 Rheumatoid arthritis; TGCT cis rs447921 0.861 rs62084971 chr17:74425318 T/G cg09812376 chr17:74270190 QRICH2 0.48 4.71 0.39 6.4e-6 Mitochondrial DNA levels; TGCT cis rs763121 1.000 rs138464 chr22:38906432 C/T cg06022373 chr22:39101656 GTPBP1 -0.7 -6.69 -0.52 6.75e-10 Menopause (age at onset); TGCT cis rs6665290 0.904 rs6677602 chr1:227187838 G/T cg10327440 chr1:227177885 CDC42BPA -0.85 -11.61 -0.72 1.54e-21 Myeloid white cell count; TGCT cis rs6725041 0.819 rs10048796 chr2:213083326 C/G cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs2115630 1.000 rs4633690 chr15:85361960 C/T cg09876464 chr15:85330779 ZNF592 0.2 4.56 0.38 1.21e-5 P wave terminal force; TGCT cis rs6089829 0.851 rs6089827 chr20:61668845 C/T cg03213289 chr20:61660250 NA 0.7 10.08 0.67 8.1e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs137603 0.966 rs470079 chr22:39708333 T/C cg17798944 chr22:39715225 SNORD43;RPL3 -0.57 -5.68 -0.45 9.16e-8 Primary biliary cholangitis; TGCT cis rs11696501 0.688 rs6104293 chr20:44326298 T/C cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs6933660 0.646 rs6911456 chr6:151778934 A/G cg17179660 chr6:151773299 C6orf211;RMND1 -0.58 -5.47 -0.44 2.41e-7 Menarche (age at onset); TGCT cis rs12479064 0.724 rs10496336 chr2:99996165 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -6.33 -0.49 4.06e-9 Chronic sinus infection; TGCT cis rs910187 0.678 rs3818009 chr20:45816514 C/T cg27589058 chr20:45804311 EYA2 -0.35 -7.58 -0.56 7.14e-12 Migraine; TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.51 -0.38 1.51e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9733 0.818 rs11204695 chr1:150657011 T/G cg13175981 chr1:150552382 MCL1 0.43 4.79 0.4 4.64e-6 Tonsillectomy; TGCT cis rs939574 0.790 rs114196239 chr2:220094307 G/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.11 5.34 0.43 4.31e-7 Platelet distribution width; TGCT cis rs611744 0.967 rs660065 chr8:109191932 G/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT trans rs10435719 0.899 rs7815595 chr8:11792351 C/A cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs17102423 0.731 rs942629 chr14:65539318 A/G cg11161011 chr14:65562177 MAX -0.46 -6.14 -0.48 1.04e-8 Obesity-related traits; TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs9300255 0.722 rs10773008 chr12:123800820 A/G cg00376283 chr12:123451042 ABCB9 0.65 4.57 0.38 1.17e-5 Neutrophil percentage of white cells; TGCT cis rs7524258 0.903 rs4908450 chr1:7292756 T/C cg04342483 chr1:7259290 CAMTA1 -0.31 -4.49 -0.37 1.6e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs4665809 1.000 rs4665309 chr2:26335502 T/C cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs514406 0.825 rs6588441 chr1:53223494 G/A cg08859206 chr1:53392774 SCP2 0.4 5.97 0.47 2.38e-8 Monocyte count; TGCT cis rs826838 1.000 rs4575342 chr12:38663831 G/A cg26384229 chr12:38710491 ALG10B 1.05 10.25 0.68 3.18e-18 Heart rate; TGCT cis rs10510102 0.872 rs7076727 chr10:123706515 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs708547 0.792 rs7667084 chr4:57727435 T/C cg25525207 chr4:57843836 C4orf14;POLR2B 0.52 4.44 0.37 1.94e-5 Response to bleomycin (chromatid breaks); TGCT cis rs12580194 0.593 rs7959124 chr12:55726957 A/G cg10672482 chr12:55725839 OR6C3 -0.56 -4.89 -0.4 3.1e-6 Cancer; TGCT trans rs4332037 0.950 rs11771828 chr7:1941003 T/C cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT cis rs7568458 0.684 rs3731828 chr2:85806266 C/T cg17127132 chr2:85788382 GGCX 0.51 4.58 0.38 1.1e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3020736 0.500 rs8143153 chr22:42515637 G/C cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs8017423 0.536 rs11625794 chr14:90811229 C/T cg04374321 chr14:90722782 PSMC1 0.52 4.93 0.4 2.61e-6 Mortality in heart failure; TGCT cis rs9393777 0.513 rs13210025 chr6:26654817 A/C cg15659132 chr6:26577336 NA -0.75 -5.25 -0.43 6.33e-7 Intelligence (multi-trait analysis); TGCT cis rs919433 0.679 rs10497806 chr2:198508951 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.03 0.41 1.68e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs853679 0.517 rs9393887 chr6:28059020 G/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs17152411 0.895 rs7079416 chr10:126587312 C/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs6460942 0.908 rs3887296 chr7:12257966 A/G cg06484146 chr7:12443880 VWDE -0.55 -4.68 -0.39 7.25e-6 Coronary artery disease; TGCT cis rs7119 0.637 rs2667775 chr15:77864802 T/G cg27398640 chr15:77910606 LINGO1 0.27 4.78 0.39 4.92e-6 Type 2 diabetes; TGCT cis rs35000415 1.000 rs35000415 chr7:128585616 C/T cg06242719 chr7:129414860 MIR183;MIR96 -0.32 -4.51 -0.38 1.5e-5 Systemic lupus erythematosus; TGCT cis rs2243480 1.000 rs316317 chr7:65613637 G/T cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs9357506 1.000 rs6911147 chr6:46307628 C/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs9473924 0.542 rs9473923 chr6:50833565 A/T cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs7666738 0.723 rs35327100 chr4:98977788 C/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3751972 0.590 rs10512428 chr17:26268925 G/C cg02948944 chr17:26242737 NA -0.45 -5.54 -0.45 1.75e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs60871478 0.636 rs7792072 chr7:886239 C/T cg15782153 chr7:917662 C7orf20 0.54 4.92 0.4 2.74e-6 Cerebrospinal P-tau181p levels; TGCT cis rs3087591 0.683 rs7502556 chr17:29642430 T/C cg24425628 chr17:29625626 OMG;NF1 0.39 5.87 0.47 3.67e-8 Hip circumference; TGCT cis rs9653442 0.900 rs4851269 chr2:100830348 C/T cg22139774 chr2:100720529 AFF3 0.38 6.18 0.49 8.42e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9430161 0.598 rs34350247 chr1:11034460 A/G cg02454025 chr1:11042201 C1orf127 0.94 11.41 0.72 4.75e-21 Ewing sarcoma; TGCT cis rs1691799 0.806 rs1168319 chr12:66744857 T/A cg16791601 chr12:66731901 HELB -0.28 -6.18 -0.49 8.52e-9 White blood cell count (basophil); TGCT cis rs1348850 0.567 rs4144276 chr2:178523420 T/C cg22681709 chr2:178499509 PDE11A -0.48 -6.19 -0.49 8.16e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs56309584 0.521 rs11651599 chr17:8179512 A/G cg08322244 chr17:8066669 VAMP2 -0.57 -5.31 -0.43 4.89e-7 Initial pursuit acceleration; TGCT cis rs17221829 0.536 rs7943784 chr11:89377310 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.13e-6 Anxiety in major depressive disorder; TGCT cis rs9921222 1.000 rs10794639 chr16:377367 A/G cg00101154 chr16:420108 MRPL28 -0.58 -7.04 -0.53 1.13e-10 Bone mineral density (spine);Bone mineral density; TGCT cis rs6669919 0.553 rs12568639 chr1:211675300 G/A cg10512769 chr1:211675356 NA -0.25 -4.6 -0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT trans rs10022799 0.725 rs9996643 chr4:168137082 G/A cg08507725 chr4:8239220 SH3TC1 0.37 6.89 0.53 2.53e-10 Cognitive function; TGCT cis rs7647973 0.554 rs13096480 chr3:49658084 A/G cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs7267979 1.000 rs2258201 chr20:25272490 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg07061783 chr6:25882402 NA -0.85 -8.68 -0.61 1.94e-14 Intelligence (multi-trait analysis); TGCT trans rs1496653 0.557 rs71317829 chr3:23325990 G/T cg02770683 chr12:57597238 LRP1 0.36 6.66 0.51 8.06e-10 Type 2 diabetes; TGCT cis rs875971 0.862 rs2460432 chr7:65554385 C/T cg11764359 chr7:65958608 NA -0.56 -4.82 -0.4 4.04e-6 Aortic root size; TGCT cis rs854572 0.600 rs854570 chr7:94952692 C/A cg19678392 chr7:94953810 PON1 0.58 6.42 0.5 2.67e-9 Paraoxonase activity; TGCT cis rs314370 0.521 rs314308 chr7:100420878 C/T cg10426581 chr7:100472382 SRRT 0.72 7.41 0.55 1.69e-11 Resting heart rate; TGCT cis rs2070488 1.000 rs34258593 chr3:38464565 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.67 0.66 8.06e-17 Electrocardiographic conduction measures; TGCT cis rs4252435 0.614 rs4252393 chr7:142628482 C/G cg09833174 chr7:143059591 FAM131B 0.88 4.64 0.38 8.69e-6 Cancer; TGCT cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg04267008 chr7:1944627 MAD1L1 -0.4 -5.3 -0.43 5.03e-7 Bipolar disorder and schizophrenia; TGCT cis rs34526934 0.619 rs17336374 chr2:177068638 T/G cg14324370 chr2:177042789 NA -0.64 -4.92 -0.4 2.72e-6 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs2735413 0.564 rs80225322 chr16:78095753 C/A cg09132178 chr16:78079569 NA 0.33 4.44 0.37 1.98e-5 Systolic blood pressure (alcohol consumption interaction); TGCT trans rs916888 0.821 rs199505 chr17:44859410 A/G cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6424115 0.679 rs2294495 chr1:24075876 C/T cg15997130 chr1:24165203 NA -0.65 -6.03 -0.48 1.73e-8 Immature fraction of reticulocytes; TGCT cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs76878669 0.754 rs10896113 chr11:66117111 C/T cg18002602 chr11:66138449 SLC29A2 -0.5 -5.71 -0.46 7.72e-8 Educational attainment (years of education); TGCT cis rs3947 0.851 rs1736089 chr8:11705870 G/A cg02840367 chr8:11660030 FDFT1 0.92 6.72 0.52 5.93e-10 Blood protein levels; TGCT cis rs8064299 0.584 rs2384957 chr17:72784630 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.87 10.03 0.67 1.06e-17 Monocyte count; TGCT cis rs66573146 1.000 rs55833486 chr4:6978729 C/A cg05069807 chr4:6945702 TBC1D14 0.32 5.01 0.41 1.83e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6964587 0.626 rs10243083 chr7:91552530 G/A cg17063962 chr7:91808500 NA -0.76 -7.25 -0.55 3.94e-11 Breast cancer; TGCT cis rs2197308 0.765 rs10880643 chr12:37926452 C/T cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs12762955 0.529 rs2387213 chr10:1051420 C/T cg26597838 chr10:835615 NA 0.46 6.13 0.48 1.1e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs7829975 0.535 rs4841005 chr8:8501230 A/G cg15556689 chr8:8085844 FLJ10661 -0.54 -5.1 -0.42 1.22e-6 Mood instability; TGCT cis rs2075371 0.501 rs1643051 chr7:134025372 A/G cg11752832 chr7:134001865 SLC35B4 -0.6 -5.21 -0.42 7.57e-7 Mean platelet volume; TGCT cis rs4788570 0.667 rs8052910 chr16:71790221 A/G cg06353428 chr16:71660113 MARVELD3 1.53 12.17 0.74 6.57e-23 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.846 rs866473 chr6:146353414 A/C cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.601 rs9393030 chr6:8516489 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9308731 0.644 rs3789065 chr2:111915022 C/G cg04202892 chr2:111875749 ACOXL 0.55 6.48 0.5 1.94e-9 Chronic lymphocytic leukemia; TGCT cis rs7246657 0.722 rs10417576 chr19:38119212 A/C cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.7e-6 Coronary artery calcification; TGCT cis rs9818758 0.607 rs5030795 chr3:49141116 C/T cg00383909 chr3:49044727 WDR6 1.18 6.77 0.52 4.48e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4803468 1.000 rs1473248 chr19:41923314 C/T cg09537434 chr19:41945824 ATP5SL 0.92 10.72 0.69 2.21e-19 Height; TGCT cis rs12477438 0.798 rs12473029 chr2:99637961 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -5.89 -0.47 3.39e-8 Chronic sinus infection; TGCT cis rs9814567 0.806 rs13076825 chr3:134317239 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.77 6.92 0.53 2.15e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs7088591 0.702 rs10491208 chr10:59703352 C/G cg15976763 chr18:24443729 AQP4 0.59 6.79 0.52 4.06e-10 Blood pressure; TGCT cis rs7584330 0.822 rs13390494 chr2:238388792 G/A cg08992911 chr2:238395768 MLPH 0.67 5.44 0.44 2.69e-7 Prostate cancer; TGCT cis rs61990749 0.544 rs176979 chr14:78198072 A/C cg23188588 chr14:78226832 SNW1;C14orf178 0.65 4.59 0.38 1.06e-5 Fibroblast growth factor basic levels; TGCT cis rs259282 0.524 rs4805006 chr19:33124136 G/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.81 0.46 4.85e-8 Schizophrenia; TGCT cis rs7772486 0.754 rs9386133 chr6:146141213 A/G cg23711669 chr6:146136114 FBXO30 0.84 9.43 0.65 3.05e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1018836 0.923 rs9693182 chr8:91621876 T/C cg16814680 chr8:91681699 NA -0.86 -9.19 -0.64 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs12701220 0.744 rs2030958 chr7:1076010 G/T cg07217954 chr7:1067459 C7orf50 -0.48 -4.7 -0.39 6.84e-6 Bronchopulmonary dysplasia; TGCT cis rs986417 1.000 rs996285 chr14:60869837 T/G cg27398547 chr14:60952738 C14orf39 -1.42 -8.68 -0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs854765 0.551 rs6502626 chr17:17849450 C/T cg09796270 chr17:17721594 SREBF1 0.23 4.46 0.37 1.82e-5 Total body bone mineral density; TGCT cis rs1023500 0.573 rs133378 chr22:42467695 G/C cg05082376 chr22:42548792 NA -0.23 -5.49 -0.44 2.21e-7 Schizophrenia; TGCT cis rs9653442 0.545 rs12987209 chr2:100761148 C/T cg22139774 chr2:100720529 AFF3 -0.36 -5.72 -0.46 7.68e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7412746 0.658 rs11204750 chr1:150939744 C/A cg04414720 chr1:150670196 GOLPH3L 0.38 4.54 0.38 1.3e-5 Melanoma; TGCT cis rs921968 0.613 rs6436066 chr2:219578361 T/G cg02176678 chr2:219576539 TTLL4 -0.34 -4.45 -0.37 1.88e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs9303401 0.573 rs62081879 chr17:57181524 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs875971 1.000 rs6961155 chr7:65933295 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs4319547 0.695 rs10734915 chr12:122873408 A/C cg08088222 chr12:122070432 ORAI1 0.25 4.45 0.37 1.89e-5 Body mass index; TGCT cis rs875971 1.000 rs6979382 chr7:65886375 C/T cg18876405 chr7:65276391 NA 0.31 4.78 0.39 4.81e-6 Aortic root size; TGCT cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg07636037 chr3:49044803 WDR6 0.86 8.75 0.62 1.33e-14 Menarche (age at onset); TGCT cis rs892961 0.932 rs7208336 chr17:75412932 T/C cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs7523273 0.606 rs2724388 chr1:207933577 T/G cg22525895 chr1:207977042 MIR29B2 0.52 8.49 0.61 5.2e-14 Schizophrenia; TGCT cis rs4409675 0.576 rs6660899 chr1:28214281 G/C cg23691781 chr1:28212827 C1orf38 0.25 5.26 0.43 6.19e-7 Corneal astigmatism; TGCT cis rs3764563 1.000 rs11673070 chr19:15746095 A/G cg20725493 chr19:15740067 CYP4F8 -0.45 -4.44 -0.37 1.93e-5 Inflammatory biomarkers; TGCT cis rs1577917 0.771 rs7452605 chr6:86240951 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 5.32 0.43 4.64e-7 Response to antipsychotic treatment; TGCT cis rs270601 0.633 rs4535443 chr5:131572561 A/G cg24060327 chr5:131705240 SLC22A5 -0.61 -6.37 -0.5 3.32e-9 Acylcarnitine levels; TGCT cis rs7949030 0.591 rs35880596 chr11:62369884 C/G cg11742103 chr11:62369870 EML3;MTA2 0.6 8.45 0.6 6.69e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10197940 0.686 rs12616688 chr2:152242099 C/G cg06191203 chr2:152266755 RIF1 -0.83 -7.95 -0.58 9.67e-13 Lung cancer; TGCT cis rs911555 0.887 rs2071407 chr14:103987140 T/C cg12935359 chr14:103987150 CKB -0.35 -5.01 -0.41 1.86e-6 Intelligence (multi-trait analysis); TGCT cis rs6988636 1.000 rs6983795 chr8:124185296 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs2562456 0.550 rs4809143 chr19:21772728 C/A cg13978929 chr19:21580086 ZNF493 -0.56 -4.72 -0.39 6.29e-6 Pain; TGCT cis rs6969780 0.722 rs4722666 chr7:27197601 C/G cg17457637 chr7:27170717 HOXA4 -0.44 -4.81 -0.4 4.29e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs1048238 0.506 rs10737911 chr1:16167855 C/T cg21385522 chr1:16154831 NA -0.6 -6.92 -0.53 2.11e-10 Systolic blood pressure; TGCT cis rs79057730 0.599 rs4333501 chr7:803244 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.66 6.27 0.49 5.39e-9 Initial pursuit acceleration; TGCT cis rs6752107 1.000 rs10165561 chr2:234172915 G/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.65 0.39 8.35e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1475911 0.671 rs12483409 chr21:43521902 G/A cg14562523 chr21:43528734 C21orf128;UMODL1 -0.27 -5.33 -0.43 4.5e-7 IgG glycosylation; TGCT cis rs4766566 0.694 rs3847952 chr12:111746678 T/G cg10833066 chr12:111807467 FAM109A 0.4 7.5 0.56 1.07e-11 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs9372498 0.536 rs62424198 chr6:118827247 A/G cg07617317 chr6:118971624 C6orf204 0.47 5.1 0.42 1.23e-6 Diastolic blood pressure; TGCT trans rs7618501 0.966 rs9882639 chr3:49799475 A/C cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs875971 0.660 rs2013222 chr7:66035936 C/G cg18876405 chr7:65276391 NA -0.41 -6.34 -0.5 3.8e-9 Aortic root size; TGCT cis rs2153535 0.580 rs9378556 chr6:8514695 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs597539 0.552 rs10896384 chr11:68720011 A/G cg04772025 chr11:68637568 NA -0.58 -6.52 -0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2303759 0.918 rs1054770 chr19:49878115 G/A cg22307029 chr19:49891270 CCDC155 0.56 5.29 0.43 5.38e-7 Multiple sclerosis; TGCT cis rs6909279 0.678 rs6557143 chr6:151848611 G/A cg14416726 chr6:151773293 C6orf211;RMND1 0.62 5.67 0.45 9.47e-8 Bone mineral density; TGCT cis rs8180040 0.845 rs295441 chr3:47333295 T/A cg27129171 chr3:47204927 SETD2 0.7 8.89 0.62 5.88e-15 Colorectal cancer; TGCT cis rs6450176 0.951 rs255757 chr5:53309371 G/A ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.58 -0.38 1.13e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs17401966 1.000 rs12141416 chr1:10327867 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.6 -0.38 1.02e-5 Hepatocellular carcinoma; TGCT cis rs6121246 0.529 rs6088814 chr20:30218172 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs4843185 0.667 rs4143865 chr16:85716612 T/A cg06784122 chr16:85688175 KIAA0182 0.27 4.51 0.38 1.46e-5 Platelet distribution width; TGCT cis rs10782582 0.593 rs2147039 chr1:76143166 C/T cg03433033 chr1:76189801 ACADM -0.66 -7.6 -0.56 6.31e-12 Daytime sleep phenotypes; TGCT cis rs2878628 0.596 rs57039206 chr3:52758570 T/A cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Intelligence (multi-trait analysis); TGCT cis rs1801251 0.893 rs6733151 chr2:233592341 A/C cg25237894 chr2:233734115 C2orf82 0.32 5.81 0.46 4.94e-8 Coronary artery disease; TGCT cis rs7824557 0.527 rs2572446 chr8:11239565 C/T cg21775007 chr8:11205619 TDH -0.68 -6.6 -0.51 1.08e-9 Retinal vascular caliber; TGCT cis rs801193 0.935 rs11772264 chr7:66176387 T/C cg18876405 chr7:65276391 NA 0.35 5.21 0.42 7.76e-7 Aortic root size; TGCT cis rs427394 0.593 rs880993 chr5:6732120 C/G cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs67311347 1.000 rs73080165 chr3:40533062 G/T cg17264618 chr3:40429014 ENTPD3 0.33 4.44 0.37 1.98e-5 Renal cell carcinoma; TGCT cis rs2070488 0.804 rs7646429 chr3:38467713 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.97 0.58 8.66e-13 Electrocardiographic conduction measures; TGCT cis rs651907 0.535 rs4342086 chr3:101503765 G/A cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs13185784 0.632 rs4469167 chr5:179650964 C/T cg04734276 chr5:178882605 NA 0.31 4.78 0.39 4.83e-6 TRAIL levels; TGCT cis rs7666738 0.830 rs6832568 chr4:98994061 G/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs114564223 chr4:119729953 A/G cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs3008870 0.583 rs17497947 chr1:67457199 G/T cg08660285 chr1:67390436 MIER1;WDR78 -0.97 -8.16 -0.59 3.17e-13 Lymphocyte percentage of white cells; TGCT cis rs4851254 0.618 rs35840153 chr2:100669829 A/G cg22139774 chr2:100720529 AFF3 -0.43 -4.63 -0.38 9.26e-6 Intelligence (multi-trait analysis); TGCT trans rs6089829 0.962 rs7267951 chr20:61665979 A/G cg13615516 chr5:77269221 NA 0.69 8.57 0.61 3.51e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7599312 0.534 rs6735626 chr2:213403972 G/A cg20637307 chr2:213403960 ERBB4 0.91 11.8 0.73 5.21e-22 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7824557 0.527 rs2736296 chr8:11234844 G/A cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.97e-9 Retinal vascular caliber; TGCT cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg03188948 chr7:1209495 NA 0.47 6.15 0.48 9.79e-9 Longevity;Endometriosis; TGCT cis rs2404602 0.647 rs10851889 chr15:77023336 C/T cg23625390 chr15:77176239 SCAPER -0.36 -4.56 -0.38 1.21e-5 Blood metabolite levels; TGCT cis rs12134245 0.776 rs61548854 chr1:92001536 C/T cg07090678 chr1:91966139 CDC7 0.35 4.75 0.39 5.58e-6 Breast cancer; TGCT cis rs79349575 0.783 rs4794000 chr17:47022755 C/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs77204473 1.000 rs17120157 chr11:116812628 C/T cg14727452 chr11:117283767 CEP164 -0.37 -4.51 -0.38 1.49e-5 Eosinophil counts;Sum eosinophil basophil counts; TGCT cis rs2742417 1.000 rs9821974 chr3:45784963 T/C cg04837898 chr3:45731254 SACM1L -0.53 -5.52 -0.44 1.92e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs4927850 1.000 rs10881564 chr3:195750326 C/T cg12923728 chr3:195709715 SDHAP1 -0.36 -7.58 -0.56 6.91e-12 Pancreatic cancer; TGCT cis rs2956278 0.717 rs2947124 chr12:84679239 C/G cg25678815 chr12:85673915 ALX1 -0.54 -4.83 -0.4 3.96e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs3806843 0.735 rs2530240 chr5:140060547 T/C cg19875535 chr5:140030758 IK -0.36 -6.15 -0.48 9.57e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2204008 0.687 rs2320523 chr12:38251397 T/C cg13010199 chr12:38710504 ALG10B 0.59 4.61 0.38 9.88e-6 Bladder cancer; TGCT cis rs10504229 0.906 rs111838497 chr8:58185620 A/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs1420338 0.933 rs10253869 chr7:34149922 A/G cg01275685 chr7:34179230 BMPER -0.27 -4.94 -0.41 2.52e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs425277 0.628 rs262662 chr1:2085033 A/G cg03732007 chr1:2071316 PRKCZ 0.28 6.63 0.51 9.05e-10 Height; TGCT cis rs986417 0.901 rs1955696 chr14:61028271 A/G cg18240143 chr14:60952599 C14orf39 0.64 4.46 0.37 1.81e-5 Gut microbiota (bacterial taxa); TGCT cis rs7666738 0.830 rs35491210 chr4:99003364 T/C cg05340658 chr4:99064831 C4orf37 0.49 5.6 0.45 1.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1371867 0.810 rs1618528 chr8:101259134 T/C cg06636551 chr8:101224915 SPAG1 0.49 6.83 0.52 3.32e-10 Atrioventricular conduction; TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg08859206 chr1:53392774 SCP2 0.48 7.82 0.57 1.97e-12 Monocyte count; TGCT cis rs2228479 0.850 rs17227064 chr16:89816314 A/G cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs9818758 0.607 rs9880088 chr3:49178990 G/A cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs10791097 0.694 rs6590520 chr11:130747386 C/G cg14779329 chr11:130786720 SNX19 0.28 4.79 0.4 4.63e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2836974 1.000 rs12710454 chr21:40656919 A/G cg17971929 chr21:40555470 PSMG1 0.94 9.06 0.63 2.38e-15 Cognitive function; TGCT cis rs13393800 0.536 rs2697804 chr2:233380020 A/G cg26635044 chr2:233757626 NGEF -0.17 -5.13 -0.42 1.09e-6 Height; TGCT cis rs7666738 0.830 rs13138920 chr4:99020786 A/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2777491 0.915 rs28583065 chr15:41608470 T/C cg18705301 chr15:41695430 NDUFAF1 -0.76 -10.72 -0.69 2.3e-19 Ulcerative colitis; TGCT cis rs4820539 1.000 rs5751589 chr22:23475762 A/G cg14186256 chr22:23484241 RTDR1 -0.97 -12.31 -0.74 2.96e-23 Bone mineral density; TGCT cis rs1153858 0.943 rs67045941 chr15:45677011 A/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs4631830 0.932 rs4581397 chr10:51532367 A/G cg10326726 chr10:51549505 MSMB -0.24 -4.92 -0.4 2.66e-6 Prostate-specific antigen levels; TGCT cis rs6940638 0.956 rs10946899 chr6:27023694 T/A cg15659132 chr6:26577336 NA -0.58 -5.4 -0.44 3.33e-7 Intelligence (multi-trait analysis); TGCT cis rs10858047 0.883 rs2137365 chr1:115078685 C/G cg12756093 chr1:115239321 AMPD1 -0.4 -4.46 -0.37 1.78e-5 Autism; TGCT cis rs7772486 0.754 rs4360151 chr6:146255079 A/C cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg05665937 chr4:1216051 CTBP1 0.25 4.68 0.39 7.33e-6 Obesity-related traits; TGCT cis rs763121 0.886 rs1013339 chr22:38974680 C/T cg06022373 chr22:39101656 GTPBP1 0.82 8.4 0.6 8.68e-14 Menopause (age at onset); TGCT cis rs6993813 0.593 rs10086835 chr8:120040181 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg03452623 chr4:187889614 NA -0.36 -5.51 -0.44 1.97e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9653442 0.564 rs2309753 chr2:100775920 C/A cg07810366 chr2:100720526 AFF3 -0.34 -5.13 -0.42 1.1e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4237845 0.611 rs10877036 chr12:58321650 A/G cg02175503 chr12:58329896 NA -0.62 -6.89 -0.53 2.45e-10 Intelligence (multi-trait analysis); TGCT cis rs12484776 0.786 rs73165040 chr22:40538602 C/T cg07138101 chr22:40742427 ADSL 0.62 4.76 0.39 5.38e-6 Uterine fibroids; TGCT trans rs877282 1.000 rs7100358 chr10:773681 G/A cg22713356 chr15:30763199 NA 1.15 9.94 0.67 1.76e-17 Uric acid levels; TGCT cis rs7611238 0.560 rs6803763 chr3:195078942 A/C cg27323046 chr3:195102265 ACAP2 0.37 4.93 0.4 2.56e-6 Body mass index; TGCT cis rs6671200 1.000 rs10747468 chr1:95686291 C/T cg20701556 chr1:95698924 RWDD3 0.62 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg18765753 chr7:1198926 ZFAND2A -0.49 -5.65 -0.45 1.03e-7 Longevity;Endometriosis; TGCT cis rs17376456 1.000 rs13154249 chr5:93550508 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs78487399 0.808 rs7591387 chr2:43756032 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.78 4.84 0.4 3.8e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2014572 0.901 rs35658377 chr19:57755627 T/G cg24459738 chr19:57751996 ZNF805 -0.54 -5.4 -0.44 3.21e-7 Hyperactive-impulsive symptoms; TGCT cis rs10504229 0.861 rs57314710 chr8:58196051 T/C cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg08048268 chr3:133502702 NA 0.69 10.86 0.7 1.01e-19 Iron status biomarkers; TGCT cis rs9308731 1.000 rs13396983 chr2:111900598 A/G cg04202892 chr2:111875749 ACOXL 0.43 4.62 0.38 9.43e-6 Chronic lymphocytic leukemia; TGCT cis rs7584330 0.554 rs6760890 chr2:238400645 G/A cg14458575 chr2:238380390 NA 0.56 5.13 0.42 1.08e-6 Prostate cancer; TGCT cis rs3785574 0.962 rs2665840 chr17:61873307 C/T cg06601766 chr17:61851465 DDX42;CCDC47 -0.57 -4.97 -0.41 2.15e-6 Height; TGCT cis rs832540 0.629 rs3309 chr5:56092779 A/T cg12311346 chr5:56204834 C5orf35 0.45 4.48 0.37 1.69e-5 Coronary artery disease; TGCT cis rs2243480 1.000 rs73142121 chr7:65311206 C/T cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg16325326 chr1:53192061 ZYG11B 0.67 7.68 0.57 4.03e-12 Monocyte count; TGCT cis rs3008870 1.000 rs912797 chr1:67413478 A/G cg03991309 chr1:68237761 GNG12 0.27 4.57 0.38 1.18e-5 Lymphocyte percentage of white cells; TGCT cis rs61867294 0.544 rs1525396 chr10:106692748 A/C cg08000847 chr10:105880925 C10orf78 0.49 4.43 0.37 2.01e-5 Schizophrenia; TGCT cis rs13326165 0.760 rs498946 chr3:52434967 T/C cg07884673 chr3:53033167 SFMBT1 0.39 4.87 0.4 3.29e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1903068 0.853 rs73236111 chr4:56019068 A/C cg09978860 chr4:56023921 NA 0.55 5.88 0.47 3.53e-8 Endometriosis; TGCT cis rs9549367 0.789 rs9549705 chr13:113888425 T/C cg00898013 chr13:113819073 PROZ -0.4 -4.92 -0.4 2.7e-6 Platelet distribution width; TGCT cis rs116095464 0.867 rs10074958 chr5:230828 C/T cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs7044106 0.791 rs735110 chr9:123488940 T/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 7.88 0.58 1.46e-12 Hip circumference adjusted for BMI; TGCT cis rs10927875 0.894 rs10927878 chr1:16319957 C/T cg21385522 chr1:16154831 NA -0.63 -7.07 -0.54 9.8e-11 Dilated cardiomyopathy; TGCT cis rs2963155 0.518 rs72801054 chr5:142687742 T/C cg17617527 chr5:142782415 NR3C1 0.84 5.71 0.46 8.05e-8 Breast cancer; TGCT cis rs6598955 0.640 rs4233460 chr1:26633387 A/G cg04990556 chr1:26633338 UBXN11 -0.92 -12.17 -0.74 6.52e-23 Obesity-related traits; TGCT cis rs9911578 1.000 rs3744108 chr17:56585872 G/C cg05425664 chr17:57184151 TRIM37 0.63 6.21 0.49 7.37e-9 Intelligence (multi-trait analysis); TGCT cis rs3087591 0.597 rs731759 chr17:29722809 A/T cg24425628 chr17:29625626 OMG;NF1 -0.37 -5.42 -0.44 2.93e-7 Hip circumference; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs9818758 0.556 rs116432667 chr3:48947589 C/T cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs13118159 0.527 rs9328733 chr4:1388583 A/G cg20887711 chr4:1340912 KIAA1530 0.95 8.36 0.6 1.08e-13 Longevity; TGCT cis rs7267979 0.702 rs449801 chr20:25491847 C/T cg13486641 chr20:25479848 NINL -0.15 -4.55 -0.38 1.28e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2933343 0.700 rs1683777 chr3:128624880 T/G cg11901034 chr3:128598214 ACAD9 -0.63 -6.06 -0.48 1.54e-8 IgG glycosylation; TGCT cis rs9926296 0.632 rs9935559 chr16:89800529 C/T cg04287289 chr16:89883240 FANCA -0.64 -6.46 -0.5 2.12e-9 Vitiligo; TGCT cis rs7666738 0.830 rs7662389 chr4:99019892 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.69 0.39 7.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2742417 0.603 rs2253979 chr3:45773320 A/G cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs10479542 0.892 rs7723230 chr5:178980474 T/C cg14820908 chr5:178986412 RUFY1 0.45 4.56 0.38 1.23e-5 Lung cancer; TGCT cis rs12497850 0.931 rs12493289 chr3:48905161 G/A cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs3748682 0.731 rs3891572 chr1:38298876 C/T cg04496824 chr1:38276835 MTF1 0.21 4.55 0.38 1.26e-5 Hypothyroidism; TGCT cis rs17221829 0.764 rs12146462 chr11:89385374 T/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs2019216 0.542 rs12450889 chr17:21889379 A/G cg22648282 chr17:21454238 C17orf51 -0.55 -5.44 -0.44 2.68e-7 Pelvic organ prolapse; TGCT cis rs12477438 0.520 rs13798 chr2:99813614 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.88 8.83 0.62 8.31e-15 Chronic sinus infection; TGCT cis rs9308731 0.644 rs56952027 chr2:111877104 C/T cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.18e-9 Chronic lymphocytic leukemia; TGCT cis rs2816958 0.708 rs2816972 chr1:200085004 A/G cg07971716 chr1:199773294 NA 0.5 4.77 0.39 5e-6 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs769267 0.965 rs7254230 chr19:19434350 C/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs13064447 0.874 rs9310408 chr3:12757726 T/C cg20675869 chr3:12750130 NA 0.19 4.92 0.4 2.68e-6 Major depression and alcohol dependence; TGCT cis rs986417 1.000 rs10149915 chr14:60943110 G/A cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg06108461 chr20:60628389 TAF4 -0.75 -11.02 -0.7 4.27e-20 Body mass index; TGCT cis rs6558174 0.802 rs6558171 chr8:22487422 T/C cg03733263 chr8:22462867 KIAA1967 0.6 4.8 0.4 4.41e-6 Breast cancer; TGCT cis rs3812831 0.695 rs3118895 chr13:114931742 G/A cg15513719 chr13:114904418 NA 0.38 4.65 0.39 8.31e-6 Schizophrenia; TGCT cis rs208520 0.690 rs207112 chr6:66792092 C/T cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs9300255 0.602 rs1626899 chr12:123708063 A/G cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs826838 0.510 rs10506129 chr12:39224242 A/T cg13010199 chr12:38710504 ALG10B 0.6 4.7 0.39 6.75e-6 Heart rate; TGCT cis rs4499344 0.622 rs7259049 chr19:33056594 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.65 -5.5 -0.44 2.1e-7 Mean platelet volume; TGCT cis rs17376456 0.825 rs28610997 chr5:93248374 T/C cg09848695 chr5:92956644 FAM172A;MIR2277 0.74 4.76 0.39 5.26e-6 Diabetic retinopathy; TGCT cis rs7091068 0.671 rs591392 chr10:95406081 G/A cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs4711350 0.765 rs943473 chr6:33743651 G/C cg00334056 chr6:33755658 LEMD2 -0.27 -4.47 -0.37 1.75e-5 Schizophrenia; TGCT cis rs6570726 0.791 rs7765687 chr6:145915100 A/C cg23711669 chr6:146136114 FBXO30 0.85 8.98 0.63 3.55e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7726839 0.540 rs72703092 chr5:599269 G/A cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Obesity-related traits; TGCT cis rs12780845 0.505 rs10795459 chr10:17244124 C/T cg01003015 chr10:17271136 VIM -0.62 -5.74 -0.46 6.8e-8 Homocysteine levels; TGCT cis rs929354 1.000 rs1182381 chr7:157043473 G/A cg05182265 chr7:156933206 UBE3C 0.3 6.31 0.49 4.59e-9 Body mass index; TGCT cis rs12579753 0.917 rs11115058 chr12:82263427 T/C cg07988820 chr12:82153109 PPFIA2 -0.51 -5.37 -0.43 3.66e-7 Resting heart rate; TGCT cis rs1609391 0.561 rs9289523 chr3:136635589 C/G cg15507776 chr3:136538369 TMEM22 0.65 6.81 0.52 3.72e-10 Neuroticism; TGCT cis rs933688 1.000 rs7720132 chr5:90745105 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 8.8 0.62 9.68e-15 Smoking behavior; TGCT cis rs11122272 0.701 rs2790894 chr1:231505587 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs112217694 0.867 rs77585392 chr4:104643797 G/A cg24090629 chr4:104641072 TACR3 -1.0 -5.19 -0.42 8.44e-7 Menarche (age at onset); TGCT cis rs1552244 1.000 rs6789156 chr3:10124120 C/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs6540559 0.673 rs17015361 chr1:210018901 C/G cg22029157 chr1:209979665 IRF6 0.68 4.88 0.4 3.22e-6 Cleft lip with or without cleft palate; TGCT trans rs629535 0.773 rs686683 chr8:70070364 G/A cg21567404 chr3:27674614 NA 0.57 9.11 0.63 1.82e-15 Dupuytren's disease; TGCT cis rs597539 0.652 rs569777 chr11:68706848 G/A cg06112835 chr11:68658793 MRPL21 0.48 8.14 0.59 3.49e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12497850 0.865 rs7649458 chr3:48920127 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs554111 0.686 rs519209 chr1:21043790 C/T cg08890418 chr1:21044141 KIF17 -0.49 -5.59 -0.45 1.41e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg13012494 chr21:47604986 C21orf56 0.4 4.88 0.4 3.21e-6 Testicular germ cell tumor; TGCT cis rs2243480 1.000 rs781156 chr7:65479141 C/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs6570726 0.846 rs870491 chr6:145933390 T/G cg23711669 chr6:146136114 FBXO30 0.83 8.67 0.61 2.02e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs9341808 0.667 rs3805919 chr6:80906809 C/G cg08355045 chr6:80787529 NA 0.3 4.98 0.41 2.07e-6 Sitting height ratio; TGCT cis rs7089973 0.604 rs7095816 chr10:116585109 T/C cg03647239 chr10:116582469 FAM160B1 0.6 5.75 0.46 6.62e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs11711311 1.000 rs13073843 chr3:113449150 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs7474896 0.559 rs2738185 chr10:38247736 G/A cg13720705 chr10:37990370 NA -0.34 -4.51 -0.38 1.46e-5 Obesity (extreme); TGCT cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6750047 1.000 rs6750047 chr2:38276549 A/G cg07380506 chr2:38303506 CYP1B1 0.62 5.63 0.45 1.12e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs7614311 0.636 rs66490742 chr3:63913653 G/A cg22134162 chr3:63841271 THOC7 -0.48 -6.11 -0.48 1.2e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs1865760 0.593 rs9295678 chr6:25937033 G/A cg12310025 chr6:25882481 NA -0.52 -5.28 -0.43 5.47e-7 Height; TGCT cis rs7302981 0.967 rs35549836 chr12:50553202 C/T cg23855989 chr12:50355821 AQP5 0.3 4.5 0.38 1.52e-5 Systolic blood pressure; TGCT trans rs324780 0.544 rs3112090 chr12:83917047 C/T cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.29e-10 Vertical cup-disc ratio; TGCT cis rs478304 0.651 rs4930313 chr11:65500428 C/T cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.05e-10 Acne (severe); TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg06753367 chr22:24256600 NA -0.23 -4.5 -0.37 1.52e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs910316 0.967 rs2024653 chr14:75595154 G/A cg08847533 chr14:75593920 NEK9 0.95 10.55 0.69 5.83e-19 Height; TGCT cis rs11190604 0.673 rs10883498 chr10:102228709 T/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4654899 0.802 rs17410008 chr1:21220701 G/C cg01072550 chr1:21505969 NA -0.47 -7.09 -0.54 8.84e-11 Superior frontal gyrus grey matter volume; TGCT cis rs36051895 0.589 rs10491650 chr9:5203054 C/T cg02405213 chr9:5042618 JAK2 0.69 8.41 0.6 8.24e-14 Pediatric autoimmune diseases; TGCT cis rs8017423 0.904 rs4603489 chr14:90760607 A/G cg04374321 chr14:90722782 PSMC1 -0.74 -7.09 -0.54 9.2e-11 Mortality in heart failure; TGCT cis rs1862618 0.671 rs2591964 chr5:56236900 T/G cg24531977 chr5:56204891 C5orf35 0.68 7.22 0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs4141404 0.748 rs2232176 chr22:31536133 A/C cg01546248 chr22:31477006 SMTN -0.61 -4.54 -0.38 1.33e-5 Paclitaxel-induced neuropathy; TGCT cis rs9811920 0.809 rs35422475 chr3:99711545 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.14 0.42 1.03e-6 Axial length; TGCT cis rs651907 0.535 rs11712309 chr3:101519097 T/C cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg11301795 chr4:187892539 NA -0.33 -4.82 -0.4 4.14e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs2727020 0.566 rs10839234 chr11:49185524 C/T cg15704280 chr7:45808275 SEPT13 -0.67 -7.51 -0.56 1.02e-11 Coronary artery disease; TGCT trans rs7618501 1.000 rs11716575 chr3:49744890 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs9796 0.516 rs28473405 chr15:41293170 C/T cg18705301 chr15:41695430 NDUFAF1 -0.5 -6.45 -0.5 2.22e-9 Menopause (age at onset); TGCT cis rs9443645 0.901 rs2050663 chr6:79753394 T/C cg09184832 chr6:79620586 NA -0.48 -5.24 -0.43 6.81e-7 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.877 rs9885329 chr5:93380278 G/A cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs9381040 0.610 rs9381028 chr6:41025081 C/A cg03526776 chr6:41159608 TREML2 0.27 5.29 0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs7829975 0.523 rs9644774 chr8:8559832 G/A cg17143192 chr8:8559678 CLDN23 -0.5 -4.92 -0.4 2.73e-6 Mood instability; TGCT cis rs2204008 0.545 rs1663283 chr12:38132039 G/A cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs1205863 1.000 rs209814 chr6:11951861 C/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs10789207 0.576 rs6690186 chr1:67003479 T/C cg22855438 chr1:67395917 MIER1 -0.7 -4.49 -0.37 1.61e-5 Resting heart rate; TGCT cis rs78487399 0.808 rs6726917 chr2:43753913 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.07 -0.41 1.41e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9814567 0.712 rs9838467 chr3:134332222 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg22166914 chr1:53195759 ZYG11B -0.36 -5.91 -0.47 3.06e-8 Monocyte count; TGCT cis rs4631830 0.900 rs7920517 chr10:51532621 G/A cg10326726 chr10:51549505 MSMB -0.27 -5.38 -0.43 3.6e-7 Prostate-specific antigen levels; TGCT cis rs13191362 1.000 rs67046187 chr6:163068532 C/A cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.86 0.52 2.88e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs797680 0.856 rs7513705 chr1:93666349 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.03 -0.41 1.67e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2836974 0.932 rs8129416 chr21:40617145 C/T cg11890956 chr21:40555474 PSMG1 1.11 12.48 0.75 1.21e-23 Cognitive function; TGCT cis rs2241685 0.850 rs7582679 chr2:1942742 A/G cg21862353 chr2:1801628 MYT1L -0.52 -4.77 -0.39 5.05e-6 Attention deficit hyperactivity disorder; TGCT cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs1552244 0.572 rs59132826 chr3:10169725 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT trans rs2070856 0.655 rs116067827 chr20:23699577 G/A cg13434034 chr8:135477110 NA 0.78 6.65 0.51 8.27e-10 Blood protein levels; TGCT cis rs2456568 0.867 rs1395384 chr11:93663250 C/T cg16099599 chr11:93583650 C11orf90 0.38 4.51 0.38 1.51e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3824867 0.676 rs7104366 chr11:47462115 G/A cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs9611565 0.506 rs1883825 chr22:41703408 A/G cg03806693 chr22:41940476 POLR3H -0.75 -7.26 -0.55 3.78e-11 Vitiligo; TGCT cis rs644799 0.672 rs11021347 chr11:95653494 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.75 7.57 0.56 7.54e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6582630 0.576 rs4403871 chr12:38292193 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs114540395 0.920 rs115066444 chr10:103461443 G/C cg18276125 chr10:102749041 C10orf2 0.42 4.92 0.4 2.65e-6 Schizophrenia; TGCT cis rs8177253 0.930 rs12595 chr3:133496553 T/C cg20276088 chr3:133502917 NA -0.24 -5.07 -0.41 1.41e-6 Iron status biomarkers; TGCT cis rs10927875 0.757 rs4661679 chr1:16321010 C/T cg21385522 chr1:16154831 NA 0.51 5.31 0.43 4.96e-7 Dilated cardiomyopathy; TGCT cis rs6087990 0.735 rs2424920 chr20:31385452 T/C cg13636640 chr20:31349939 DNMT3B 0.95 12.38 0.74 2.08e-23 Ulcerative colitis; TGCT cis rs9902453 0.934 rs7211246 chr17:28485762 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs13256369 1.000 rs13267501 chr8:8574058 G/A cg06671706 chr8:8559999 CLDN23 0.35 4.62 0.38 9.35e-6 Obesity-related traits; TGCT cis rs4919694 1.000 rs78893207 chr10:104796138 T/C cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs5769765 0.908 rs138864 chr22:50204712 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.38 5.75 0.46 6.53e-8 Schizophrenia; TGCT cis rs9914544 0.564 rs11868520 chr17:18770367 A/G cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs1862618 0.641 rs252893 chr5:56224714 T/C cg20203395 chr5:56204925 C5orf35 -0.53 -4.92 -0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs858239 0.665 rs858305 chr7:23242830 C/G cg05407003 chr7:23246146 NA 0.28 4.52 0.38 1.43e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs617219 0.737 rs13158309 chr5:78463395 C/T cg23514016 chr5:78407564 BHMT -0.34 -5.17 -0.42 9.08e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT trans rs6089829 0.889 rs6090206 chr20:61668363 G/A cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT trans rs6951245 0.554 rs10270249 chr7:1151886 G/T cg13565492 chr6:43139072 SRF -0.81 -7.71 -0.57 3.45e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7192750 0.586 rs8050651 chr16:71881444 C/G cg06353428 chr16:71660113 MARVELD3 0.8 7.26 0.55 3.8e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2836974 0.545 rs3167757 chr21:40714478 C/T cg11644478 chr21:40555479 PSMG1 0.63 6.09 0.48 1.34e-8 Cognitive function; TGCT trans rs1814175 0.817 rs10839351 chr11:49758153 C/T cg03929089 chr4:120376271 NA -0.69 -7.97 -0.58 8.64e-13 Height; TGCT cis rs9926296 0.569 rs4785708 chr16:89796569 C/T cg03388025 chr16:89894329 SPIRE2 -0.31 -4.63 -0.38 9.05e-6 Vitiligo; TGCT cis rs250677 1.000 rs250676 chr5:148425518 A/T cg23229984 chr5:148520753 ABLIM3 0.21 4.98 0.41 2.05e-6 Breast cancer; TGCT cis rs921968 0.509 rs832813 chr2:219354569 T/C cg02176678 chr2:219576539 TTLL4 0.46 6.6 0.51 1.08e-9 Mean corpuscular hemoglobin concentration; TGCT trans rs561341 0.654 rs6505265 chr17:30172580 C/T cg20587970 chr11:113659929 NA 0.67 8.2 0.59 2.57e-13 Hip circumference adjusted for BMI; TGCT cis rs7267979 1.000 rs404394 chr20:25447896 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs951366 0.903 rs823114 chr1:205719532 G/A cg24503407 chr1:205819492 PM20D1 0.42 5.17 0.42 9.1e-7 Menarche (age at onset); TGCT cis rs9308731 0.644 rs7593638 chr2:111876941 A/C cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.1e-9 Chronic lymphocytic leukemia; TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg09177884 chr7:1199841 ZFAND2A -0.6 -6.31 -0.49 4.58e-9 Longevity;Endometriosis; TGCT cis rs2820315 1.000 rs2820309 chr1:201834944 A/G cg12730843 chr1:201915899 LMOD1 -0.25 -4.54 -0.38 1.32e-5 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2456568 0.778 rs7940973 chr11:93682045 C/G cg26875233 chr11:93583750 C11orf90 0.41 5.22 0.42 7.28e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3931020 0.530 rs12125889 chr1:75241971 A/G cg17719053 chr1:75198211 TYW3;CRYZ 0.48 4.81 0.4 4.32e-6 Resistin levels; TGCT cis rs2948294 0.566 rs13261997 chr8:8112295 C/T cg15462221 chr8:8086144 FLJ10661 -0.59 -4.82 -0.4 4.11e-6 Red cell distribution width; TGCT cis rs3540 0.960 rs8030722 chr15:90974920 G/A cg22089800 chr15:90895588 ZNF774 0.74 6.88 0.53 2.59e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2980439 0.783 rs2948305 chr8:8098577 G/A cg15556689 chr8:8085844 FLJ10661 0.88 9.0 0.63 3.23e-15 Neuroticism; TGCT cis rs7617773 0.780 rs6442111 chr3:48312060 G/C cg11946769 chr3:48343235 NME6 0.72 6.2 0.49 7.83e-9 Coronary artery disease; TGCT cis rs6460942 0.908 rs6978768 chr7:12232366 G/A cg06484146 chr7:12443880 VWDE -0.53 -4.6 -0.38 1.03e-5 Coronary artery disease; TGCT cis rs77741769 0.571 rs1696357 chr12:121348649 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.45 0.37 1.87e-5 Mean corpuscular volume; TGCT cis rs7226408 0.857 rs72887052 chr18:34487296 A/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7772486 0.790 rs2256998 chr6:146207657 A/C cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6912958 0.559 rs107690 chr6:88069352 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.68 -7.08 -0.54 9.23e-11 Monocyte percentage of white cells; TGCT cis rs12579753 1.000 rs7966755 chr12:82221604 A/G cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs8072100 0.840 rs12453233 chr17:45454570 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.09 -0.42 1.28e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs763014 0.966 rs4984904 chr16:680809 C/G cg00908189 chr16:619842 PIGQ 0.87 10.68 0.69 2.85e-19 Height; TGCT cis rs17376456 0.569 rs12653528 chr5:93212833 T/C cg25358565 chr5:93447407 FAM172A -0.81 -6.54 -0.51 1.47e-9 Diabetic retinopathy; TGCT cis rs1061377 0.965 rs7677729 chr4:39121990 C/T cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs62064224 0.533 rs11657826 chr17:30790386 T/A cg18200150 chr17:30822561 MYO1D 0.59 8.48 0.61 5.5e-14 Schizophrenia; TGCT cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg25811766 chr13:21894605 NA 0.28 5.38 0.44 3.53e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs67311347 0.544 rs13062243 chr3:40336789 G/A cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs2239547 0.657 rs12496077 chr3:52886241 G/A cg11645453 chr3:52864694 ITIH4 0.35 5.77 0.46 5.97e-8 Schizophrenia; TGCT cis rs13082711 0.554 rs13087873 chr3:27392326 C/T cg02860705 chr3:27208620 NA 0.43 6.0 0.47 2.03e-8 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7264396 0.690 rs2425170 chr20:34442672 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.27 -4.47 -0.37 1.76e-5 Total cholesterol levels; TGCT cis rs4242434 0.927 rs3736147 chr8:22471824 A/G cg21658235 chr8:22456391 C8orf58 -0.43 -4.5 -0.37 1.54e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9549367 0.826 rs9549710 chr13:113898064 A/C cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs13392177 0.660 rs10932762 chr2:219076213 G/C cg00012203 chr2:219082015 ARPC2 -0.79 -8.02 -0.58 6.73e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg18654377 chr3:49208889 KLHDC8B -0.38 -5.03 -0.41 1.69e-6 Menarche (age at onset); TGCT cis rs77861329 1.000 rs876782 chr3:52107909 C/T cg08692210 chr3:52188851 WDR51A -0.84 -4.56 -0.38 1.2e-5 Macrophage inflammatory protein 1b levels; TGCT cis rs6933660 0.676 rs3757316 chr6:151774339 A/G cg10883421 chr6:151773342 RMND1;C6orf211 -0.82 -9.11 -0.63 1.79e-15 Menarche (age at onset); TGCT cis rs7267979 1.000 rs6083813 chr20:25337671 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6089829 0.925 rs3746748 chr20:61667526 C/T cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs7666738 0.927 rs4699328 chr4:99055890 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.26 0.43 6.03e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.724 rs16922734 chr8:58111192 C/T cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs2404602 0.716 rs7179142 chr15:76698268 G/A cg26408565 chr15:76604113 ETFA -0.41 -5.42 -0.44 2.92e-7 Blood metabolite levels; TGCT cis rs1801251 0.963 rs6739638 chr2:233576015 G/A cg25237894 chr2:233734115 C2orf82 0.31 5.52 0.44 1.92e-7 Coronary artery disease; TGCT cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.33e-9 Electroencephalogram traits; TGCT cis rs5771225 0.544 rs1555048 chr22:50688348 A/G cg16473166 chr22:50639996 SELO 0.67 5.37 0.43 3.68e-7 Late-onset Alzheimer's disease; TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg03724423 chr7:27170755 HOXA4 -0.43 -4.59 -0.38 1.05e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6700896 0.500 rs4655754 chr1:66114747 C/T cg14976592 chr1:65886160 LEPROT;LEPR -0.57 -4.56 -0.38 1.19e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs12620999 0.878 rs59725626 chr2:237970010 G/A cg23555395 chr2:238036564 NA 0.28 4.97 0.41 2.19e-6 Systemic lupus erythematosus; TGCT cis rs7666738 0.753 rs11097594 chr4:98944486 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6901250 0.568 rs4946198 chr6:117176599 C/T cg12892004 chr6:117198278 RFX6 -0.47 -5.37 -0.43 3.7e-7 C-reactive protein levels; TGCT cis rs8067545 0.717 rs9907788 chr17:20008903 T/C cg13482628 chr17:19912719 NA 0.53 4.51 0.38 1.49e-5 Schizophrenia; TGCT cis rs1124769 0.502 rs12148865 chr15:51078597 C/G cg23028286 chr15:51614521 CYP19A1 0.2 4.51 0.38 1.46e-5 Cognitive performance; TGCT cis rs2153535 0.601 rs9502715 chr6:8455709 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs11030122 0.702 rs1349583 chr11:3972236 G/A cg18678763 chr11:4115507 RRM1 -0.49 -6.27 -0.49 5.56e-9 Mean platelet volume;Platelet distribution width; TGCT cis rs2658782 0.951 rs2608214 chr11:93148665 C/T cg18152523 chr11:93063302 CCDC67 -0.62 -5.14 -0.42 1.03e-6 Pulmonary function decline; TGCT trans rs8073060 0.586 rs9303690 chr17:34005513 C/T cg19694781 chr19:47549865 TMEM160 -0.62 -14.07 -0.78 1.86e-27 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2230307 0.536 rs496798 chr1:100507990 G/A cg24955406 chr1:100503596 HIAT1 0.74 4.86 0.4 3.41e-6 Carotid intima media thickness; TGCT cis rs7017914 0.905 rs2639960 chr8:71922139 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs6032067 0.929 rs2664581 chr20:43804522 A/C cg16667508 chr20:43936853 MATN4;RBPJL -0.39 -4.96 -0.41 2.31e-6 Blood protein levels; TGCT cis rs1008375 1.000 rs10009541 chr4:17682218 C/T cg10189774 chr4:17578691 LAP3 -0.53 -4.69 -0.39 7.14e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7647973 0.961 rs11130186 chr3:49275828 A/G cg05785598 chr3:49045655 WDR6 0.39 4.61 0.38 9.91e-6 Menarche (age at onset); TGCT cis rs8033133 0.881 rs3803328 chr15:25330550 T/A cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.27 -5.09 -0.42 1.32e-6 Blood osmolality (transformed sodium); TGCT cis rs7829975 0.539 rs883647 chr8:8569724 G/A cg17143192 chr8:8559678 CLDN23 -0.52 -5.14 -0.42 1.02e-6 Mood instability; TGCT cis rs6770219 0.516 rs7635507 chr3:186134871 G/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs9467773 1.000 rs6926629 chr6:26499903 T/C cg15659132 chr6:26577336 NA 0.84 11.93 0.73 2.59e-22 Intelligence (multi-trait analysis); TGCT cis rs7258465 1.000 rs8105994 chr19:18593553 A/G cg06462663 chr19:18546047 ISYNA1 0.21 4.76 0.39 5.35e-6 Breast cancer; TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg05215272 chr17:6899095 ALOX12 -0.51 -6.29 -0.49 4.9e-9 Tonsillectomy; TGCT cis rs2562456 0.793 rs7259708 chr19:21750648 T/C cg25650185 chr19:21324782 ZNF431 -0.66 -5.86 -0.47 3.92e-8 Pain; TGCT cis rs2276314 0.857 rs28530656 chr18:33588700 C/T cg19628046 chr18:33552617 C18orf21 -0.51 -4.46 -0.37 1.79e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs11792861 0.926 rs3750451 chr9:111822866 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.47 0.37 1.73e-5 Menarche (age at onset); TGCT cis rs7824557 0.614 rs17741537 chr8:11213092 A/G cg21775007 chr8:11205619 TDH 0.71 6.81 0.52 3.73e-10 Retinal vascular caliber; TGCT cis rs7681440 0.904 rs28734152 chr4:90767359 C/T cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs12681288 0.644 rs2123058 chr8:1000304 A/G cg04851639 chr8:1020857 NA -0.29 -4.8 -0.4 4.54e-6 Schizophrenia; TGCT cis rs7178572 0.568 rs11854193 chr15:77458136 C/A cg15453836 chr15:77711506 NA -0.45 -4.99 -0.41 2.02e-6 Type 2 diabetes; TGCT cis rs477895 1.000 rs7939107 chr11:64034773 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.32 0.43 4.6e-7 Mean platelet volume; TGCT cis rs6952808 0.609 rs34967784 chr7:1949507 T/G cg22963979 chr7:1858916 MAD1L1 -0.39 -5.89 -0.47 3.36e-8 Bipolar disorder and schizophrenia; TGCT cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg15659132 chr6:26577336 NA -0.55 -5.37 -0.43 3.7e-7 Schizophrenia; TGCT cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg09177884 chr7:1199841 ZFAND2A -0.48 -4.55 -0.38 1.27e-5 Longevity;Endometriosis; TGCT cis rs3087591 0.922 rs2341348 chr17:29534867 C/T cg24425628 chr17:29625626 OMG;NF1 0.48 6.99 0.53 1.52e-10 Hip circumference; TGCT cis rs4665809 0.567 rs6711402 chr2:26430983 A/G cg25036284 chr2:26402008 FAM59B -0.74 -5.29 -0.43 5.28e-7 Gut microbiome composition (summer); TGCT cis rs9311474 0.713 rs352170 chr3:52236077 A/G cg07507251 chr3:52567010 NT5DC2 0.4 5.32 0.43 4.68e-7 Electroencephalogram traits; TGCT cis rs769267 0.930 rs6909 chr19:19619542 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs9513627 0.573 rs12431100 chr13:100184918 C/G cg15490075 chr13:100150979 NA -0.68 -4.55 -0.38 1.25e-5 Obesity-related traits; TGCT cis rs2677744 0.962 rs1266486 chr15:91460284 T/C cg23684204 chr15:91497937 RCCD1 0.34 5.15 0.42 1e-6 Attention deficit hyperactivity disorder; TGCT cis rs9810089 0.786 rs10935183 chr3:136149139 C/T cg12473912 chr3:136751656 NA 0.36 5.1 0.42 1.22e-6 Gestational age at birth (child effect); TGCT cis rs75229567 0.618 rs35394896 chr12:70188346 T/A cg10114359 chr12:70132523 RAB3IP 1.06 5.95 0.47 2.6e-8 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT trans rs1814175 0.791 rs10839395 chr11:49846274 G/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs2115536 1.000 rs11072871 chr15:80197931 T/C cg00225070 chr15:80189496 MTHFS 0.58 5.15 0.42 9.94e-7 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs35306767 0.714 rs7075188 chr10:1088746 G/T cg20503657 chr10:835505 NA -0.45 -4.91 -0.4 2.87e-6 Eosinophil percentage of granulocytes; TGCT trans rs916888 0.821 rs199514 chr17:44856881 G/A cg07870213 chr5:140052090 DND1 -0.61 -7.28 -0.55 3.35e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs231513 0.906 rs179586 chr17:41999094 T/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.03 -0.41 1.67e-6 Cognitive function; TGCT cis rs2535633 0.602 rs2581816 chr3:53014657 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.55 -5.32 -0.43 4.66e-7 Body mass index; TGCT cis rs1215050 0.765 rs783925 chr4:98969881 T/C cg17366294 chr4:99064904 C4orf37 -0.55 -5.8 -0.46 5.23e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs910316 0.967 rs175502 chr14:75533679 A/G cg08847533 chr14:75593920 NEK9 -0.95 -10.3 -0.68 2.33e-18 Height; TGCT cis rs10984561 0.881 rs7039410 chr9:122251769 T/G cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs7208859 0.623 rs7217984 chr17:29092766 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2688608 0.592 rs7909802 chr10:75484186 G/C cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs6088580 0.634 rs4911423 chr20:32999386 T/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs67311347 1.000 rs6795475 chr3:40489281 A/G cg13683864 chr3:40499215 RPL14 -1.04 -10.81 -0.7 1.34e-19 Renal cell carcinoma; TGCT cis rs7017914 0.905 rs2639951 chr8:71927225 C/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs3091242 0.933 rs35497030 chr1:25783066 A/G cg00786635 chr1:25594202 NA -0.52 -5.54 -0.45 1.71e-7 Erythrocyte sedimentation rate; TGCT trans rs2727020 0.729 rs2866328 chr11:49282421 A/G cg15704280 chr7:45808275 SEPT13 0.73 8.33 0.6 1.27e-13 Coronary artery disease; TGCT cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg24250549 chr1:154909240 PMVK 0.66 6.5 0.5 1.73e-9 Prostate cancer; TGCT cis rs9467773 1.000 rs3736782 chr6:26505403 C/A cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT cis rs3087591 0.922 rs757383 chr17:29596045 C/G cg24425628 chr17:29625626 OMG;NF1 0.47 7.46 0.56 1.3e-11 Hip circumference; TGCT cis rs896854 1.000 rs896854 chr8:95960511 T/C cg23172400 chr8:95962367 TP53INP1 -0.38 -6.49 -0.5 1.84e-9 Type 2 diabetes; TGCT cis rs1153858 1.000 rs4625670 chr15:45652926 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs765787 0.530 rs11854690 chr15:45516016 C/T cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT trans rs9650657 0.513 rs7005884 chr8:10796472 A/G cg15556689 chr8:8085844 FLJ10661 -0.8 -7.38 -0.55 1.96e-11 Neuroticism; TGCT cis rs1218582 0.741 rs10908446 chr1:154869559 G/A cg03351412 chr1:154909251 PMVK 0.53 4.83 0.4 3.89e-6 Prostate cancer; TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg07157834 chr1:205819609 PM20D1 0.42 6.65 0.51 8.2e-10 Menarche (age at onset); TGCT cis rs9457247 0.846 rs2757052 chr6:167380174 T/C cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.08e-6 Crohn's disease; TGCT cis rs8017423 0.647 rs12883357 chr14:90815032 A/G cg04374321 chr14:90722782 PSMC1 -0.57 -5.6 -0.45 1.33e-7 Mortality in heart failure; TGCT cis rs7267979 1.000 rs7343481 chr20:25300113 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs561341 0.883 rs1034626 chr17:30219500 C/G cg20587970 chr11:113659929 NA 0.8 9.45 0.65 2.65e-16 Hip circumference adjusted for BMI; TGCT cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg09323728 chr8:95962352 TP53INP1 -0.44 -5.26 -0.43 6.04e-7 Type 2 diabetes; TGCT cis rs7193541 0.684 rs4888265 chr16:74683737 T/C cg01733217 chr16:74700730 RFWD3 1.0 13.03 0.76 5.7e-25 Multiple myeloma; TGCT cis rs6674176 1.000 rs11210937 chr1:44405563 T/C cg13606994 chr1:44402422 ARTN -0.52 -5.07 -0.41 1.39e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6089829 0.962 rs9679865 chr20:61666132 C/G cg08045932 chr20:61659980 NA 0.49 9.25 0.64 8.4e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs56255635 chr8:58178264 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6430585 0.528 rs309166 chr2:136667487 C/T cg07169764 chr2:136633963 MCM6 1.19 11.56 0.72 2.02e-21 Corneal structure; TGCT cis rs7804356 1.000 rs73065521 chr7:26831409 C/A cg03456212 chr7:26904342 SKAP2 -0.62 -4.71 -0.39 6.51e-6 Type 1 diabetes; TGCT cis rs9394841 0.692 rs9381095 chr6:41806708 T/A cg08135965 chr6:41755394 TOMM6 0.54 4.96 0.41 2.31e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs9993613 0.875 rs11728435 chr4:73509826 T/C cg15102770 chr4:73434591 ADAMTS3 0.52 4.87 0.4 3.28e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs1005277 0.579 rs1740749 chr10:38521646 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4517514 0.509 rs11018894 chr11:89904238 C/A cg05041596 chr11:89867385 NAALAD2 0.55 5.14 0.42 1.05e-6 Trans fatty acid levels; TGCT cis rs12220238 1.000 rs11000901 chr10:75919971 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs12136530 0.593 rs11578302 chr1:19724835 A/G cg24875000 chr1:19041556 PAX7 -0.27 -4.61 -0.38 9.8200000000000008e-06 Lead levels in blood; TGCT cis rs36051895 0.664 rs3824433 chr9:5113577 C/T cg02405213 chr9:5042618 JAK2 -0.75 -10.29 -0.68 2.45e-18 Pediatric autoimmune diseases; TGCT cis rs7666738 0.830 rs13144771 chr4:99026935 G/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.861 rs551435 chr1:53260537 G/T cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs17108533 0.588 rs35201218 chr14:71302023 C/T cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs4918072 0.798 rs2067831 chr10:105643223 G/C cg11005552 chr10:105648138 OBFC1 0.4 5.28 0.43 5.58e-7 Coronary artery disease; TGCT cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg03452623 chr4:187889614 NA -0.36 -5.34 -0.43 4.32e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs1496653 0.602 rs35027557 chr3:23552752 C/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs10504229 0.609 rs56289889 chr8:58116276 G/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs4273100 0.790 rs60166680 chr17:19277544 C/G cg23267110 chr17:19140637 EPN2 -0.74 -4.48 -0.37 1.68e-5 Schizophrenia; TGCT cis rs947211 0.846 rs823155 chr1:205762946 T/C cg24503407 chr1:205819492 PM20D1 0.43 4.48 0.37 1.67e-5 Parkinson's disease; TGCT cis rs208515 0.525 rs12193034 chr6:66677866 C/T cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs72843506 0.656 rs16959946 chr17:20172447 A/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.92 -0.4 2.67e-6 Schizophrenia; TGCT cis rs2404602 0.967 rs2083762 chr15:76907376 T/C cg26408565 chr15:76604113 ETFA -0.37 -4.65 -0.39 8.21e-6 Blood metabolite levels; TGCT cis rs2836950 0.501 rs11088470 chr21:40689162 A/G cg06238570 chr21:40685208 BRWD1 -0.63 -6.44 -0.5 2.42e-9 Menarche (age at onset); TGCT cis rs2742417 1.000 rs2673034 chr3:45755138 A/G cg04837898 chr3:45731254 SACM1L -0.52 -5.28 -0.43 5.58e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7829975 0.593 rs2921077 chr8:8304502 C/T cg06636001 chr8:8085503 FLJ10661 0.73 7.19 0.54 5.43e-11 Mood instability; TGCT cis rs4808199 0.948 rs12982276 chr19:19459800 T/C cg03709012 chr19:19516395 GATAD2A 0.8 6.46 0.5 2.13e-9 Nonalcoholic fatty liver disease; TGCT cis rs2742417 1.000 rs1877933 chr3:45753487 C/T cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7044106 0.762 rs12003646 chr9:123470621 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 6.83 0.52 3.4e-10 Hip circumference adjusted for BMI; TGCT cis rs28785552 0.931 rs10406850 chr19:53240807 A/C cg10871876 chr19:53194124 ZNF83 0.57 8.16 0.59 3.1400000000000003e-13 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg27170947 chr2:26402098 FAM59B -0.43 -4.48 -0.37 1.69e-5 Gut microbiome composition (summer); TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg16145915 chr7:1198662 ZFAND2A -0.61 -8.69 -0.62 1.8e-14 Longevity;Endometriosis; TGCT cis rs7666738 0.518 rs13133925 chr4:98706398 G/T cg18180107 chr4:99064573 C4orf37 0.54 4.78 0.39 4.93e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs13121558 chr4:99002848 G/A cg18180107 chr4:99064573 C4orf37 0.5 4.46 0.37 1.79e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs1406084 0.636 rs3842900 chr2:154717391 G/C cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs6088590 0.687 rs6088580 chr20:33285053 G/C cg06115741 chr20:33292138 TP53INP2 0.57 4.86 0.4 3.51e-6 Coronary artery disease; TGCT trans rs17685 0.884 rs8565 chr7:75630274 T/C cg19862616 chr7:65841803 NCRNA00174 -0.47 -7.26 -0.55 3.81e-11 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs892961 0.932 rs312853 chr17:75406045 T/G cg05865280 chr17:75406074 SEPT9 0.27 6.69 0.52 6.81e-10 Airflow obstruction; TGCT cis rs67311347 0.544 rs2278927 chr3:40350447 G/A cg13683864 chr3:40499215 RPL14 -0.8 -7.58 -0.56 6.86e-12 Renal cell carcinoma; TGCT cis rs763121 0.853 rs2179142 chr22:39037954 G/A cg06022373 chr22:39101656 GTPBP1 0.81 7.91 0.58 1.21e-12 Menopause (age at onset); TGCT cis rs11252926 0.537 rs61836851 chr10:447231 T/C cg18196295 chr10:418757 DIP2C 0.3 4.89 0.4 3.1e-6 Psychosis in Alzheimer's disease; TGCT cis rs597539 0.690 rs497149 chr11:68626639 A/T cg06112835 chr11:68658793 MRPL21 0.48 8.13 0.59 3.78e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6952808 0.929 rs12532128 chr7:1925454 T/C cg22963979 chr7:1858916 MAD1L1 -0.35 -5.5 -0.44 2.08e-7 Bipolar disorder and schizophrenia; TGCT cis rs3862260 0.509 rs10802124 chr1:120164252 G/A cg11530693 chr1:120165357 ZNF697 0.21 4.75 0.39 5.48e-6 Systemic lupus erythematosus; TGCT cis rs67311347 1.000 rs9849992 chr3:40402140 C/T cg13683864 chr3:40499215 RPL14 -1.1 -11.83 -0.73 4.49e-22 Renal cell carcinoma; TGCT cis rs2797160 1.000 rs4897153 chr6:126003403 A/G cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs611744 0.967 rs678387 chr8:109242730 G/C cg21045802 chr8:109455806 TTC35 0.5 4.57 0.38 1.18e-5 Dupuytren's disease; TGCT cis rs7169223 0.615 rs8038189 chr15:79099026 G/C cg03762349 chr15:79060523 ADAMTS7 -0.25 -4.91 -0.4 2.83e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs12579753 0.810 rs1922565 chr12:82135348 T/C cg21231944 chr12:82153410 PPFIA2 -0.33 -4.48 -0.37 1.68e-5 Resting heart rate; TGCT cis rs910187 0.624 rs6063077 chr20:45787261 C/T cg27589058 chr20:45804311 EYA2 -0.36 -6.75 -0.52 4.97e-10 Migraine; TGCT cis rs9381040 0.610 rs2294694 chr6:41046177 G/A cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs9611565 0.559 rs4822048 chr22:41988225 C/T cg03806693 chr22:41940476 POLR3H -1.11 -11.64 -0.72 1.26e-21 Vitiligo; TGCT cis rs4704846 1.000 rs6861025 chr5:156519097 C/T cg12943317 chr5:156479607 HAVCR1 -0.31 -4.56 -0.38 1.21e-5 Blood protein levels; TGCT cis rs6424115 0.557 rs35904775 chr1:24180623 T/C cg15997130 chr1:24165203 NA -0.91 -10.51 -0.69 7.36e-19 Immature fraction of reticulocytes; TGCT cis rs2439831 0.850 rs558656 chr15:43723514 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs669446 0.558 rs620851 chr1:44110489 A/G cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs2932538 0.922 rs3790611 chr1:113067792 A/G cg22162597 chr1:113214053 CAPZA1 0.27 5.92 0.47 2.95e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs4689388 0.890 rs11732208 chr4:6292716 G/C cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs739401 0.595 rs402806 chr11:3066432 A/G cg25174290 chr11:3078921 CARS 0.47 4.5 0.37 1.53e-5 Longevity; TGCT cis rs9486715 1.000 rs9373985 chr6:97063522 C/G cg06623918 chr6:96969491 KIAA0776 -1.08 -13.52 -0.77 3.67e-26 Headache; TGCT trans rs5771242 0.518 rs6010216 chr22:50679471 C/T cg26607758 chr8:91997553 NA 0.72 7.33 0.55 2.55e-11 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs10931896 0.531 rs296801 chr2:201142812 C/T cg17644776 chr2:200775616 C2orf69 0.27 4.8 0.4 4.45e-6 Systolic blood pressure; TGCT cis rs739496 0.843 rs583140 chr12:111985954 G/A cg10833066 chr12:111807467 FAM109A 0.35 4.52 0.38 1.42e-5 Platelet count; TGCT cis rs9443645 0.670 rs79209669 chr6:79719623 C/G cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.559 rs11769861 chr7:106979559 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs13242816 1.000 rs35800776 chr7:116110069 C/A cg02799643 chr7:116139180 CAV2 -0.45 -4.84 -0.4 3.76e-6 P wave duration; TGCT cis rs2760061 0.599 rs849903 chr1:228137659 T/C cg18477163 chr1:228402036 OBSCN -0.32 -6.21 -0.49 7.19e-9 Diastolic blood pressure; TGCT cis rs3796352 1.000 rs35576914 chr3:53092270 G/A cg27565382 chr3:53032988 SFMBT1 0.43 4.6 0.38 1.01e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs5769765 0.825 rs7511620 chr22:50307932 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.44 6.19 0.49 8.01e-9 Schizophrenia; TGCT cis rs11711311 1.000 rs9830978 chr3:113455940 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs67311347 1.000 rs2305522 chr3:40429358 A/G cg13683864 chr3:40499215 RPL14 -1.05 -11.13 -0.71 2.2e-20 Renal cell carcinoma; TGCT cis rs9902453 0.872 rs34698290 chr17:28500465 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.56 0.51 1.32e-9 Coffee consumption (cups per day); TGCT cis rs6427419 0.934 rs874844 chr1:158067047 A/C cg07184316 chr1:157669111 FCRL3 0.24 4.52 0.38 1.43e-5 Obesity-related traits; TGCT cis rs12926788 0.689 rs1862450 chr16:24856775 A/G cg06028605 chr16:24865363 SLC5A11 -0.43 -4.87 -0.4 3.34e-6 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1577917 0.958 rs12205492 chr6:86475976 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.48 -0.44 2.28e-7 Response to antipsychotic treatment; TGCT cis rs12142240 0.738 rs41293275 chr1:46806429 A/T cg00530320 chr1:46809349 NSUN4 0.29 5.95 0.47 2.58e-8 Menopause (age at onset); TGCT cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg16049864 chr8:95962084 TP53INP1 -0.72 -10.19 -0.67 4.46e-18 Type 2 diabetes; TGCT cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs12142240 0.698 rs55971480 chr1:46823206 G/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7781977 0.644 rs10269380 chr7:50354512 G/A cg01139861 chr7:50343298 IKZF1 0.5 5.91 0.47 3.13e-8 IgG glycosylation; TGCT cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg01802117 chr1:53393560 SCP2 0.47 5.77 0.46 5.88e-8 Monocyte count; TGCT cis rs4499344 1.000 rs4499344 chr19:33073431 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.79 -7.14 -0.54 6.92e-11 Mean platelet volume; TGCT cis rs6750047 0.932 rs2116232 chr2:38268718 C/A cg07380506 chr2:38303506 CYP1B1 0.59 5.28 0.43 5.71e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs6671200 1.000 rs259346 chr1:95728746 G/T cg20701556 chr1:95698924 RWDD3 0.67 5.63 0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs4638749 1.000 rs12616140 chr2:108867728 A/G cg06795125 chr2:108905320 SULT1C2 -0.37 -4.69 -0.39 6.95e-6 Blood pressure; TGCT cis rs1800469 1.000 rs1982072 chr19:41864509 T/A cg09537434 chr19:41945824 ATP5SL -0.51 -4.64 -0.38 8.66e-6 Colorectal cancer; TGCT cis rs4285028 0.747 rs9824235 chr3:121432177 G/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.91 -6.89 -0.53 2.47e-10 Multiple sclerosis; TGCT cis rs6840360 0.606 rs10028035 chr4:152347825 T/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT trans rs916888 0.821 rs199513 chr17:44856932 A/G cg22433210 chr17:43662623 NA -0.9 -6.71 -0.52 6.31e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4319547 0.728 rs61954974 chr12:123074169 T/C cg23029597 chr12:123009494 RSRC2 -0.3 -4.92 -0.4 2.65e-6 Body mass index; TGCT cis rs2303759 0.874 rs8108669 chr19:49845895 C/T cg22307029 chr19:49891270 CCDC155 0.55 5.14 0.42 1.02e-6 Multiple sclerosis; TGCT cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg16497277 chr3:49208875 KLHDC8B -0.54 -5.2 -0.42 7.97e-7 Menarche (age at onset); TGCT cis rs826838 0.935 rs1160162 chr12:38959795 G/A cg13010199 chr12:38710504 ALG10B 0.8 6.77 0.52 4.58e-10 Heart rate; TGCT cis rs12291225 0.585 rs4517475 chr11:14386145 A/G cg19336497 chr11:14380999 RRAS2 -0.46 -7.45 -0.56 1.38e-11 Sense of smell; TGCT cis rs17221829 0.829 rs11018737 chr11:89427132 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.46 -0.37 1.83e-5 Anxiety in major depressive disorder; TGCT cis rs763121 0.853 rs2072794 chr22:39150543 G/T cg06022373 chr22:39101656 GTPBP1 0.76 6.73 0.52 5.68e-10 Menopause (age at onset); TGCT cis rs7216064 1.000 rs4569324 chr17:65872750 C/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs12477438 0.520 rs12621007 chr2:99791946 G/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.31 0.77 1.16e-25 Chronic sinus infection; TGCT cis rs10504229 1.000 rs66936919 chr8:58172868 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs10540 1.000 rs12417570 chr11:462684 C/T cg03934478 chr11:495069 RNH1 0.33 5.08 0.42 1.33e-6 Body mass index; TGCT cis rs2204008 0.570 rs12318341 chr12:38251087 T/C cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Bladder cancer; TGCT cis rs9467711 0.606 rs72841536 chr6:26378288 T/A cg16898833 chr6:26189333 HIST1H4D 1.1 5.3 0.43 5.01e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg18538332 chr22:24372958 LOC391322 -0.88 -9.89 -0.66 2.28e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7681440 0.746 rs1442134 chr4:90819154 A/G cg20003494 chr4:90757398 SNCA -0.53 -4.94 -0.41 2.42e-6 Dementia with Lewy bodies; TGCT cis rs1218582 0.741 rs10908446 chr1:154869559 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.67 -6.63 -0.51 9.37e-10 Prostate cancer; TGCT cis rs9682041 0.696 rs6786542 chr3:170105378 C/T cg11886554 chr3:170076028 SKIL 0.62 4.82 0.4 4.11e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs711830 1.000 rs1549334 chr2:177039197 G/A cg13092806 chr2:177043255 NA 0.74 5.95 0.47 2.58e-8 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs10504229 0.815 rs16921955 chr8:58164553 C/T cg24829409 chr8:58192753 C8orf71 -0.51 -4.45 -0.37 1.88e-5 Developmental language disorder (linguistic errors); TGCT cis rs644799 1.000 rs568668 chr11:95528209 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7552404 0.921 rs10873685 chr1:76218818 A/C cg22875332 chr1:76189707 ACADM 0.78 9.11 0.63 1.8e-15 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs1814175 0.935 rs11040438 chr11:49622521 G/A cg11707556 chr5:10655725 ANKRD33B -0.34 -6.67 -0.51 7.47e-10 Height; TGCT cis rs3820068 0.581 rs72645861 chr1:15920314 A/G cg05660106 chr1:15850417 CASP9 0.84 8.27 0.6 1.8e-13 Systolic blood pressure; TGCT cis rs7216064 0.953 rs4791048 chr17:65848994 G/A cg12091567 chr17:66097778 LOC651250 -0.84 -6.8 -0.52 4.01e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs854765 0.583 rs66531105 chr17:17809001 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.77 0.57 2.63e-12 Total body bone mineral density; TGCT cis rs4918072 0.917 rs35041090 chr10:105648686 G/A cg11005552 chr10:105648138 OBFC1 0.4 5.34 0.43 4.26e-7 Coronary artery disease; TGCT cis rs10858047 0.883 rs7556270 chr1:115178041 T/C cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs10504229 0.906 rs2270609 chr8:58194684 G/A cg24829409 chr8:58192753 C8orf71 -0.55 -4.83 -0.4 3.91e-6 Developmental language disorder (linguistic errors); TGCT cis rs6696846 0.691 rs11240370 chr1:205118336 T/G cg03948781 chr1:205179583 DSTYK 0.34 4.47 0.37 1.72e-5 Red blood cell count; TGCT cis rs11992186 0.597 rs77717027 chr8:8591632 T/C cg17143192 chr8:8559678 CLDN23 -0.51 -5.02 -0.41 1.79e-6 Neuroticism; TGCT cis rs11731606 0.508 rs17021533 chr4:95280587 C/T cg00507259 chr4:95128692 SMARCAD1 0.63 4.72 0.39 6.18e-6 Mean platelet volume; TGCT cis rs1023500 0.507 rs6002600 chr22:42488906 G/A cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Schizophrenia; TGCT cis rs6598955 0.671 rs6686100 chr1:26617338 G/C cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs155076 0.666 rs2015241 chr13:21888254 A/G cg14456004 chr13:21872349 NA 1.25 12.41 0.74 1.76e-23 White matter hyperintensity burden; TGCT cis rs9291683 0.527 rs73212848 chr4:10093299 T/C cg11266682 chr4:10021025 SLC2A9 -0.57 -6.84 -0.52 3.15e-10 Bone mineral density; TGCT cis rs9583531 0.600 rs7330080 chr13:111367115 C/T cg24331049 chr13:111365604 ING1 0.74 7.15 0.54 6.44e-11 Coronary artery disease; TGCT cis rs17125944 0.505 rs75838476 chr14:53242362 G/A cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg13695892 chr22:41940480 POLR3H -0.93 -9.17 -0.64 1.26e-15 Vitiligo; TGCT cis rs644799 1.000 rs564675 chr11:95561873 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs35146811 0.844 rs4729576 chr7:99692594 G/A cg13334819 chr7:99746414 C7orf59 -0.81 -6.91 -0.53 2.23e-10 Coronary artery disease; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg21672276 chr3:44754072 ZNF502 -0.52 -5.92 -0.47 2.97e-8 Depressive symptoms; TGCT cis rs7681440 0.935 rs3756059 chr4:90757272 G/A cg20003494 chr4:90757398 SNCA -0.61 -5.77 -0.46 5.89e-8 Dementia with Lewy bodies; TGCT cis rs4788570 0.615 rs2334880 chr16:71653637 A/G cg06353428 chr16:71660113 MARVELD3 1.55 13.15 0.76 2.84e-25 Intelligence (multi-trait analysis); TGCT cis rs950169 0.922 rs4842939 chr15:84827966 C/T cg11189052 chr15:85197271 WDR73 -0.8 -6.6 -0.51 1.07e-9 Schizophrenia; TGCT cis rs12220898 0.749 rs4310533 chr10:50482625 C/G cg25968469 chr10:49687287 ARHGAP22 0.25 4.47 0.37 1.78e-5 Inflammatory biomarkers; TGCT cis rs2072499 1.000 rs2241107 chr1:156182710 C/T cg25208724 chr1:156163844 SLC25A44 -1.08 -15.52 -0.81 7.74e-31 Testicular germ cell tumor; TGCT cis rs67478160 0.619 rs11628481 chr14:104241499 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.57 -0.51 1.25e-9 Schizophrenia; TGCT cis rs740474 0.652 rs251022 chr5:140892643 T/C cg00076195 chr5:140892677 NA 0.42 4.86 0.4 3.42e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs57221529 0.766 rs12519469 chr5:581772 A/G cg09021430 chr5:549028 NA -0.37 -5.3 -0.43 5.09e-7 Lung disease severity in cystic fibrosis; TGCT cis rs8062405 0.540 rs480400 chr16:28574615 A/G cg09754948 chr16:28834200 ATXN2L 0.54 4.52 0.38 1.41e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs12210905 1.000 rs72843607 chr6:27110715 C/A cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs7949030 0.626 rs11231154 chr11:62362293 A/G cg22862634 chr11:62369728 EML3;MTA2 0.7 8.89 0.62 5.98e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2456568 0.571 rs1105113 chr11:93693323 G/A cg17595323 chr11:93583763 C11orf90 0.38 4.62 0.38 9.46e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6952808 0.630 rs4719443 chr7:2161099 A/G cg22963979 chr7:1858916 MAD1L1 -0.39 -6.52 -0.51 1.63e-9 Bipolar disorder and schizophrenia; TGCT cis rs17270561 0.579 rs10456326 chr6:25919662 G/A cg17042849 chr6:26104293 HIST1H4C -0.78 -5.66 -0.45 9.93e-8 Iron status biomarkers; TGCT cis rs10782582 0.609 rs2881785 chr1:76318096 T/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.47 0.37 1.72e-5 Daytime sleep phenotypes; TGCT cis rs9311474 0.629 rs7636227 chr3:52566682 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.84 0.52 3.14e-10 Electroencephalogram traits; TGCT cis rs2120019 0.938 rs8040169 chr15:75370958 C/A cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs4727027 0.704 rs2269972 chr7:148914047 C/T cg23583168 chr7:148888333 NA 0.83 10.69 0.69 2.62e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9303401 0.659 rs12946397 chr17:56769979 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs2688608 0.620 rs7098444 chr10:75580042 C/T cg19442545 chr10:75533431 FUT11 -0.36 -5.67 -0.45 9.61e-8 Inflammatory bowel disease; TGCT cis rs2463822 1.000 rs11231050 chr11:62131660 C/G cg06239285 chr11:62104954 ASRGL1 -0.91 -6.69 -0.51 7e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs4919669 0.777 rs5011218 chr10:104401218 A/C cg05855489 chr10:104503620 C10orf26 0.76 4.44 0.37 1.98e-5 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs6582630 0.548 rs1607870 chr12:38385964 G/T cg26384229 chr12:38710491 ALG10B -0.52 -4.51 -0.38 1.5e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs8103278 0.507 rs1865116 chr19:46294510 G/A cg14061069 chr19:46274453 DMPK 0.62 10.67 0.69 3.04e-19 Coronary artery disease; TGCT cis rs9467711 0.606 rs9358936 chr6:26370657 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2242116 1.000 rs2168443 chr3:46947087 A/T cg27129171 chr3:47204927 SETD2 -0.59 -5.71 -0.46 7.93e-8 Birth weight; TGCT trans rs877282 0.838 rs11253408 chr10:796374 T/C cg22713356 chr15:30763199 NA 1.18 10.55 0.69 5.81e-19 Uric acid levels; TGCT cis rs1023500 0.529 rs133375 chr22:42466509 C/G cg05082376 chr22:42548792 NA -0.23 -5.44 -0.44 2.75e-7 Schizophrenia; TGCT cis rs769267 0.930 rs7256149 chr19:19566255 T/C cg03709012 chr19:19516395 GATAD2A 0.75 6.2 0.49 7.59e-9 Tonsillectomy; TGCT cis rs7829975 0.577 rs79495969 chr8:8545250 G/A cg17143192 chr8:8559678 CLDN23 -0.52 -5.21 -0.42 7.57e-7 Mood instability; TGCT cis rs9302001 0.960 rs9524624 chr13:95464661 G/A cg07483244 chr13:95358924 NA 0.37 4.76 0.39 5.29e-6 Panic disorder; TGCT cis rs4566357 0.615 rs10198406 chr2:227913539 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -5.25 -0.43 6.53e-7 Coronary artery disease; TGCT cis rs9638182 0.725 rs7797566 chr7:72896395 A/C cg14087351 chr7:73037990 MLXIPL -0.57 -4.52 -0.38 1.4e-5 Triglycerides; TGCT trans rs1005277 0.579 rs1780115 chr10:38524773 C/T cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7829975 0.533 rs7820146 chr8:8699757 T/A cg06636001 chr8:8085503 FLJ10661 0.71 6.25 0.49 6.17e-9 Mood instability; TGCT cis rs6089829 0.926 rs7273917 chr20:61665975 G/A cg03213289 chr20:61660250 NA 0.7 10.02 0.67 1.14e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs8030485 0.728 rs28415942 chr15:79384850 C/T cg17916960 chr15:79447300 NA 0.33 4.49 0.37 1.63e-5 Left ventricle wall thickness; TGCT cis rs9911578 1.000 rs2009948 chr17:56611920 A/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs3809566 1.000 rs3809566 chr15:63333724 A/G cg24483493 chr15:63333476 TPM1 -0.26 -4.46 -0.37 1.85e-5 Platelet count; TGCT cis rs10750165 0.644 rs10790343 chr11:119630480 A/G cg18567470 chr11:120208005 ARHGEF12 0.42 4.7 0.39 6.91e-6 Aggressiveness in attention deficit hyperactivity disorder; TGCT cis rs7208859 0.573 rs60724269 chr17:29113273 G/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3796352 0.892 rs11718388 chr3:53076415 G/A cg07884673 chr3:53033167 SFMBT1 0.6 6.24 0.49 6.25e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9611565 0.625 rs12483991 chr22:41935285 A/G cg06481639 chr22:41940642 POLR3H -0.63 -5.76 -0.46 6.21e-8 Vitiligo; TGCT cis rs7258465 1.000 rs4808136 chr19:18618867 A/G cg06462663 chr19:18546047 ISYNA1 -0.21 -4.78 -0.39 4.86e-6 Breast cancer; TGCT cis rs7095607 0.813 rs7088768 chr10:69933421 A/T cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.72e-6 Lung function (FVC); TGCT cis rs72772090 0.522 rs17398914 chr5:96005180 A/C cg19084281 chr5:95765746 PCSK1 0.56 4.47 0.37 1.77e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg11941060 chr3:133502564 NA -0.3 -6.41 -0.5 2.69e-9 Iron status biomarkers; TGCT cis rs4494114 0.629 rs9439074 chr1:39296300 G/A cg25970120 chr1:39325951 RRAGC -0.52 -5.02 -0.41 1.74e-6 Blood protein levels; TGCT cis rs896854 0.738 rs509594 chr8:95967156 C/G cg23172400 chr8:95962367 TP53INP1 0.36 5.6 0.45 1.29e-7 Type 2 diabetes; TGCT cis rs427394 0.659 rs274678 chr5:6752385 A/G cg10857441 chr5:6722123 POLS 0.29 5.91 0.47 3.09e-8 Menopause (age at onset); TGCT cis rs8017423 0.647 rs12883844 chr14:90820519 T/C cg04374321 chr14:90722782 PSMC1 -0.56 -5.62 -0.45 1.19e-7 Mortality in heart failure; TGCT cis rs1499614 1.000 rs2707838 chr7:66159201 C/T cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs5750830 0.594 rs9611169 chr22:39783027 C/T cg24399712 chr22:39784796 NA -0.92 -10.84 -0.7 1.17e-19 Intelligence (multi-trait analysis); TGCT cis rs9911578 0.967 rs2429369 chr17:56501420 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.16 -0.48 9.42e-9 Intelligence (multi-trait analysis); TGCT cis rs6735179 0.643 rs10200618 chr2:1746140 A/C cg20311673 chr2:1746207 PXDN 0.27 4.49 0.37 1.59e-5 Response to antipsychotic treatment; TGCT cis rs7312933 0.703 rs11181378 chr12:42600658 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs28595532 0.920 rs55758547 chr4:119769475 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs526231 0.853 rs187579 chr5:102604933 A/C cg05225461 chr5:102596755 C5orf30 0.23 4.62 0.38 9.51e-6 Primary biliary cholangitis; TGCT cis rs344364 0.511 rs2982447 chr16:1947413 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 0.44 4.91 0.4 2.75e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.871 rs60342323 chr8:58154899 T/C cg08280861 chr8:58055591 NA 0.37 4.8 0.4 4.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.932 rs1985737 chr20:25591468 T/A cg16686733 chr20:25566563 NINL 0.55 5.54 0.45 1.7e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17331151 0.573 rs3755801 chr3:52865798 G/A cg27565382 chr3:53032988 SFMBT1 0.46 5.89 0.47 3.45e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4372836 0.504 rs10183665 chr2:28995226 A/G cg09522027 chr2:28974177 PPP1CB -0.52 -5.22 -0.42 7.4e-7 Body mass index; TGCT cis rs9467773 0.935 rs1056668 chr6:26510605 C/T cg09904177 chr6:26538194 HMGN4 0.58 5.6 0.45 1.28e-7 Intelligence (multi-trait analysis); TGCT cis rs7226408 0.857 rs72887032 chr18:34473233 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6964587 1.000 rs6974607 chr7:91750116 G/A cg22709100 chr7:91322751 NA 0.28 4.55 0.38 1.25e-5 Breast cancer; TGCT trans rs1814175 0.817 rs12277258 chr11:49940216 T/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs7617773 0.780 rs36121690 chr3:48345511 C/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs28595532 0.920 rs116023344 chr4:119760263 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs7769051 0.711 rs6569847 chr6:133083187 C/A cg07930552 chr6:133119739 C6orf192 0.88 4.57 0.38 1.18e-5 Type 2 diabetes nephropathy; TGCT cis rs2486288 0.656 rs11632651 chr15:45550838 C/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs12908161 0.959 rs61074241 chr15:85333396 C/T cg17173187 chr15:85201210 NMB 0.51 5.56 0.45 1.56e-7 Schizophrenia; TGCT cis rs76878669 0.793 rs7924580 chr11:66080770 C/T cg18002602 chr11:66138449 SLC29A2 -0.52 -5.71 -0.46 8.01e-8 Educational attainment (years of education); TGCT cis rs72615157 0.628 rs7801070 chr7:99847147 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.63 -5.16 -0.42 9.65e-7 Lung function (FEV1/FVC); TGCT cis rs78487399 0.665 rs6753942 chr2:43749436 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.68 -0.39 7.51e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6867032 0.958 rs4975797 chr5:2015573 G/A cg26168224 chr5:2018326 NA 0.43 7.82 0.57 2e-12 Gut microbiome composition (winter); TGCT cis rs1865760 0.516 rs9295684 chr6:26069669 T/C cg17042849 chr6:26104293 HIST1H4C -0.66 -5.85 -0.47 4.02e-8 Height; TGCT cis rs2562456 0.561 rs12610883 chr19:21750059 A/G cg25650185 chr19:21324782 ZNF431 -0.66 -5.86 -0.47 3.92e-8 Pain; TGCT cis rs7192750 0.586 rs12444521 chr16:71941698 A/T cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2404602 0.716 rs66754747 chr15:76828568 G/A cg22467129 chr15:76604101 ETFA -0.48 -5.53 -0.44 1.81e-7 Blood metabolite levels; TGCT cis rs2201841 0.921 rs12567232 chr1:67728018 G/A cg25131922 chr1:68698529 GPR177 0.44 4.66 0.39 8.11e-6 Ulcerative colitis;Psoriasis;Crohn's disease; TGCT cis rs9303401 0.659 rs17822807 chr17:56687190 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs6724607 1.000 rs6434402 chr2:191469322 C/T cg21644426 chr2:191273491 MFSD6 -0.6 -5.91 -0.47 3.12e-8 Pulse pressure; TGCT cis rs1008375 0.966 rs4698636 chr4:17632834 T/C cg10189774 chr4:17578691 LAP3 0.64 5.81 0.46 4.97e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs17685 0.712 rs60232511 chr7:75800082 A/G cg19862616 chr7:65841803 NCRNA00174 0.5 8.46 0.6 6.36e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs826838 1.000 rs11514441 chr12:38775190 C/T cg13010199 chr12:38710504 ALG10B 0.82 6.86 0.52 2.91e-10 Heart rate; TGCT cis rs916888 0.531 rs183211 chr17:44788310 G/A cg01570182 chr17:44337453 NA 0.76 7.25 0.55 3.88e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7772486 0.686 rs7739735 chr6:146123536 G/A cg05347473 chr6:146136440 FBXO30 0.47 4.48 0.37 1.7e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs17270561 0.887 rs12201170 chr6:25866247 A/G cg16482183 chr6:26056742 HIST1H1C 0.87 5.67 0.45 9.5e-8 Iron status biomarkers; TGCT cis rs2882877 0.735 rs994227 chr2:190432467 T/C cg10752008 chr2:190445175 SLC40A1 0.67 5.26 0.43 6.24e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg06481639 chr22:41940642 POLR3H -0.73 -6.64 -0.51 8.91e-10 Vitiligo; TGCT cis rs3806843 0.576 rs155360 chr5:140309016 C/T cg09824255 chr5:140014002 CD14 0.25 4.54 0.38 1.32e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs1008375 1.000 rs7654345 chr4:17691796 A/G cg18681998 chr4:17616180 MED28 0.76 7.28 0.55 3.42e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12478296 0.901 rs56318767 chr2:243046591 T/A cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs9467773 0.620 rs2451711 chr6:26663110 A/G cg05738196 chr6:26577821 NA 0.88 10.71 0.69 2.37e-19 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs6088590 1.000 rs3787222 chr20:33333040 T/A cg06115741 chr20:33292138 TP53INP2 0.68 5.69 0.45 8.67e-8 Coronary artery disease; TGCT cis rs739496 0.615 rs602276 chr12:112133924 G/A cg10833066 chr12:111807467 FAM109A 0.37 4.79 0.39 4.76e-6 Platelet count; TGCT cis rs1215050 0.791 rs1648546 chr4:98899294 T/C cg05340658 chr4:99064831 C4orf37 -0.46 -5.82 -0.46 4.74e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs875971 0.862 rs7796162 chr7:65745758 T/C cg11764359 chr7:65958608 NA -0.54 -4.86 -0.4 3.45e-6 Aortic root size; TGCT cis rs597539 0.617 rs672853 chr11:68636362 G/A cg21963583 chr11:68658836 MRPL21 0.36 6.1 0.48 1.25e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7412746 0.658 rs57818453 chr1:150763139 G/A cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs561341 0.739 rs1978116 chr17:30220978 A/C cg13647721 chr17:30228624 UTP6 0.62 4.92 0.4 2.72e-6 Hip circumference adjusted for BMI; TGCT cis rs929354 0.772 rs1182441 chr7:157026650 A/G cg05182265 chr7:156933206 UBE3C 0.4 9.05 0.63 2.54e-15 Body mass index; TGCT cis rs2742417 0.624 rs2673068 chr3:45768981 G/A cg04837898 chr3:45731254 SACM1L -0.63 -6.62 -0.51 9.64e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs4644046 0.515 rs10948625 chr6:51429472 G/C cg14391730 chr6:52021665 NA 0.31 4.46 0.37 1.8e-5 Coronary artery disease; TGCT cis rs2692947 0.526 rs58719199 chr2:96578247 G/A cg13655245 chr2:97463316 CNNM4 0.15 4.51 0.38 1.48e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg12310025 chr6:25882481 NA -0.65 -5.86 -0.47 3.84e-8 Intelligence (multi-trait analysis); TGCT cis rs938554 0.571 rs7696092 chr4:10025320 C/A cg11266682 chr4:10021025 SLC2A9 0.56 5.5 0.44 2.05e-7 Blood metabolite levels; TGCT cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg03264133 chr6:25882463 NA -0.86 -8.32 -0.6 1.32e-13 Intelligence (multi-trait analysis); TGCT cis rs8072100 0.539 rs36043200 chr17:45629406 G/A cg08085267 chr17:45401833 C17orf57 0.47 5.15 0.42 1.01e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs17376456 1.000 rs9968691 chr5:93509756 C/G cg25358565 chr5:93447407 FAM172A 0.95 7.97 0.58 8.71e-13 Diabetic retinopathy; TGCT cis rs4689592 0.554 rs66925245 chr4:7071999 C/T cg02503808 chr4:7069936 GRPEL1 -1.01 -8.75 -0.62 1.27e-14 Monocyte percentage of white cells; TGCT cis rs13108904 0.967 rs13150571 chr4:1278636 C/G cg03303774 chr4:1407052 NA 0.31 4.87 0.4 3.31e-6 Obesity-related traits; TGCT cis rs12900413 0.603 rs2882677 chr15:90299514 C/T cg24249390 chr15:90295951 MESP1 -0.29 -5.11 -0.42 1.19e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs9859260 0.744 rs539816 chr3:195784076 T/A cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs9611565 0.512 rs139566 chr22:42199277 A/G cg13695892 chr22:41940480 POLR3H -0.86 -8.04 -0.59 6.03e-13 Vitiligo; TGCT cis rs9467773 1.000 rs2393670 chr6:26535541 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.659 rs111723629 chr1:46853361 G/T cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs7714584 1.000 rs114244137 chr5:150264753 C/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs1867631 1.000 rs11208928 chr1:67089562 G/T cg13052034 chr1:66999238 SGIP1 0.59 4.93 0.41 2.53e-6 Menopause (age at onset); TGCT cis rs6500602 0.727 rs6500607 chr16:4503631 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.26 4.9 0.4 2.95e-6 Schizophrenia; TGCT cis rs4788570 0.615 rs9888756 chr16:71740477 G/A cg06353428 chr16:71660113 MARVELD3 1.55 12.69 0.75 3.63e-24 Intelligence (multi-trait analysis); TGCT cis rs8013055 0.796 rs4074937 chr14:106000977 A/G cg23356831 chr14:105996513 TMEM121 0.39 6.45 0.5 2.22e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7255045 0.742 rs10407116 chr19:12962272 G/A cg06537894 chr19:12978706 MAST1 -0.49 -4.48 -0.37 1.69e-5 Mean corpuscular volume; TGCT cis rs10769945 0.592 rs1635155 chr11:1972919 G/T cg06679296 chr11:1949032 TNNT3 -0.25 -4.57 -0.38 1.16e-5 DNA methylation (variation); TGCT cis rs9905759 0.603 rs4130509 chr17:7930778 C/T cg15403654 chr17:7747012 KDM6B 0.46 4.95 0.41 2.39e-6 Childhood ear infection; TGCT cis rs12681287 0.640 rs7816629 chr8:87350788 A/T cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs10782582 0.593 rs12126155 chr1:76131555 C/G cg03433033 chr1:76189801 ACADM -0.64 -7.32 -0.55 2.78e-11 Daytime sleep phenotypes; TGCT cis rs4665809 0.590 rs72809668 chr2:26467653 C/T cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs11673344 0.583 rs7254411 chr19:37525871 G/A cg08039142 chr19:36980659 ZNF566 0.52 4.83 0.4 3.9e-6 Obesity-related traits; TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.12 0.54 7.78e-11 Prudent dietary pattern; TGCT cis rs968567 0.638 rs7943728 chr11:61547068 G/A cg19610905 chr11:61596333 FADS2 -0.8 -4.9 -0.4 2.96e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs1008375 0.931 rs979823 chr4:17700176 G/A cg18681998 chr4:17616180 MED28 0.8 7.63 0.57 5.41e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2439831 0.850 rs12441984 chr15:44126285 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT cis rs9325144 0.647 rs11168104 chr12:38857616 G/T cg10518543 chr12:38710700 ALG10B -0.48 -4.46 -0.37 1.84e-5 Morning vs. evening chronotype; TGCT cis rs7312933 0.566 rs11181454 chr12:42746486 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.7 -0.46 8.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10992471 0.565 rs12552866 chr9:95110549 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.63 -6.13 -0.48 1.1e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7568458 0.591 rs55971080 chr2:85812746 T/C cg02493740 chr2:85810744 VAMP5 -0.34 -6.31 -0.49 4.52e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7584330 0.780 rs937395 chr2:238378749 T/C cg14458575 chr2:238380390 NA 0.51 8.41 0.6 8.33e-14 Prostate cancer; TGCT cis rs6500602 0.627 rs9938228 chr16:4530597 T/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 4.92 0.4 2.73e-6 Schizophrenia; TGCT cis rs7818688 0.697 rs11784140 chr8:95987480 G/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7523273 0.526 rs558248 chr1:208047435 A/G cg22525895 chr1:207977042 MIR29B2 -0.33 -5.35 -0.43 4.02e-7 Schizophrenia; TGCT cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg15556689 chr8:8085844 FLJ10661 -0.84 -9.23 -0.64 9.23e-16 Neuroticism; TGCT cis rs4925386 0.840 rs6142738 chr20:60919960 C/T cg06026331 chr20:60912101 LAMA5 -0.4 -6.81 -0.52 3.82e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs62380364 0.602 rs640177 chr5:88002084 T/A cg22951263 chr5:87985283 NA -0.61 -6.53 -0.51 1.49e-9 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs892961 0.932 rs67415822 chr17:75412678 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT trans rs561341 0.556 rs41290963 chr17:30396390 C/T cg20587970 chr11:113659929 NA -1.0 -8.24 -0.59 2.08e-13 Hip circumference adjusted for BMI; TGCT cis rs12472274 0.941 rs11677230 chr2:239092054 T/C cg17459225 chr2:239074497 NA 0.33 4.88 0.4 3.23e-6 Phospholipid levels (plasma); TGCT cis rs1519814 0.668 rs7836786 chr8:121006826 G/A cg22335954 chr8:121166405 COL14A1 -0.36 -4.55 -0.38 1.26e-5 Breast cancer; TGCT cis rs7598759 0.548 rs11693738 chr2:232360484 C/T cg19187155 chr2:232395269 NMUR1 0.48 5.62 0.45 1.2e-7 Noise-induced hearing loss; TGCT cis rs13191362 0.507 rs1079020 chr6:163066596 C/T cg21926612 chr6:163149169 PACRG;PARK2 -0.6 -5.29 -0.43 5.44e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs79149102 0.579 rs7181942 chr15:75300623 G/C cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs929354 1.000 rs1182452 chr7:157053618 G/A cg05182265 chr7:156933206 UBE3C 0.32 6.63 0.51 9.07e-10 Body mass index; TGCT cis rs7809950 1.000 rs10273733 chr7:107258121 A/G cg23024343 chr7:107201750 COG5 0.3 4.62 0.38 9.29e-6 Coronary artery disease; TGCT trans rs561341 1.000 rs473356 chr17:30321762 G/C cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs1843834 0.539 rs1494109 chr2:225441833 G/A cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs1971256 0.500 rs6925359 chr6:151798783 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.74 -4.49 -0.37 1.63e-5 Endometriosis; TGCT cis rs36051895 0.632 rs11788963 chr9:5120157 C/A cg02405213 chr9:5042618 JAK2 -0.71 -9.55 -0.65 1.57e-16 Pediatric autoimmune diseases; TGCT cis rs7589728 0.563 rs4972044 chr2:88466196 T/C cg04511125 chr2:88470314 THNSL2 0.83 6.93 0.53 2e-10 Plasma clusterin levels; TGCT cis rs7666738 0.830 rs1111541 chr4:99033860 A/G cg18180107 chr4:99064573 C4orf37 -0.59 -5.4 -0.44 3.23e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8072100 0.575 rs1221385 chr17:45527574 T/G cg08085267 chr17:45401833 C17orf57 -0.43 -4.61 -0.38 9.85e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7618915 0.547 rs8906 chr3:52739520 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs9633740 1.000 rs7097656 chr10:82250831 T/C cg01528321 chr10:82214614 TSPAN14 1.0 8.33 0.6 1.25e-13 Post bronchodilator FEV1; TGCT cis rs950169 0.959 rs12911210 chr15:84792083 A/C cg12863693 chr15:85201151 NMB 0.39 4.62 0.38 9.33e-6 Schizophrenia; TGCT cis rs4665809 0.627 rs35461456 chr2:26482361 C/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs7568458 0.846 rs6547621 chr2:85774676 G/A cg02493740 chr2:85810744 VAMP5 -0.29 -5.47 -0.44 2.37e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs763014 0.932 rs34498660 chr16:666149 A/G cg27436995 chr16:743998 FBXL16 -0.47 -5.13 -0.42 1.07e-6 Height; TGCT cis rs9929218 0.507 rs62057805 chr16:68742390 G/C cg01251360 chr16:68772225 CDH1 -0.25 -4.57 -0.38 1.18e-5 Colorectal cancer; TGCT cis rs12477438 0.834 rs11903311 chr2:99701807 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.92 -9.58 -0.65 1.29e-16 Chronic sinus infection; TGCT cis rs875971 0.830 rs4718358 chr7:65973668 T/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.65e-6 Aortic root size; TGCT cis rs5750830 0.645 rs756640 chr22:39779300 G/A cg01416388 chr22:39784598 NA -0.63 -6.3 -0.49 4.69e-9 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.622 rs10815143 chr9:5009541 G/A cg02405213 chr9:5042618 JAK2 -0.78 -11.02 -0.7 4.05e-20 Pediatric autoimmune diseases; TGCT cis rs6912958 0.500 rs4707352 chr6:87929705 G/A cg10393598 chr6:87862264 NA 0.3 4.44 0.37 1.99e-5 Monocyte percentage of white cells; TGCT cis rs1218582 0.772 rs6656435 chr1:154876869 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs9549260 0.753 rs4943794 chr13:41173408 G/C cg21288729 chr13:41239152 FOXO1 0.67 4.68 0.39 7.31e-6 Red blood cell count; TGCT cis rs7552404 0.696 rs1417405 chr1:76457797 T/C cg22875332 chr1:76189707 ACADM 0.63 5.51 0.44 1.97e-7 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10791097 0.694 rs7926167 chr11:130745045 T/C cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7208859 0.623 rs9899268 chr17:29150255 T/C cg13385521 chr17:29058706 SUZ12P 0.81 4.85 0.4 3.68e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.830 rs10516426 chr4:99035827 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs72781680 0.898 rs56303870 chr2:24086944 G/A cg08917208 chr2:24149416 ATAD2B 0.77 4.69 0.39 7.06e-6 Lymphocyte counts; TGCT cis rs12681288 0.523 rs112307130 chr8:962483 G/A cg04851639 chr8:1020857 NA -0.29 -4.76 -0.39 5.27e-6 Schizophrenia; TGCT cis rs6540559 1.000 rs6659367 chr1:209982408 G/T cg23283495 chr1:209979779 IRF6 0.67 5.7 0.46 8.12e-8 Cleft lip with or without cleft palate; TGCT cis rs2180341 0.618 rs12210968 chr6:127596985 A/G cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs9926296 0.682 rs258328 chr16:89730314 C/T cg01097406 chr16:89675127 NA 0.34 5.88 0.47 3.54e-8 Vitiligo; TGCT cis rs12479064 0.724 rs6748200 chr2:100080895 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.73 -6.42 -0.5 2.58e-9 Chronic sinus infection; TGCT cis rs10493773 0.775 rs11161662 chr1:86185040 A/G cg17807903 chr1:86174739 ZNHIT6 -0.43 -6.18 -0.49 8.46e-9 Urate levels in overweight individuals; TGCT cis rs6121246 0.529 rs6060210 chr20:30187681 C/T cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs4072705 0.967 rs4838208 chr9:127528035 C/A cg13476313 chr9:127244764 NR5A1 0.28 4.57 0.38 1.18e-5 Menarche (age at onset); TGCT cis rs6121246 0.909 rs1075698 chr20:30387992 G/C cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg13395646 chr4:1353034 KIAA1530 -0.41 -5.08 -0.42 1.33e-6 Longevity; TGCT cis rs9581857 0.579 rs75872792 chr13:27996064 G/T cg22138327 chr13:27999177 GTF3A 0.81 5.55 0.45 1.68e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7617773 0.817 rs9834095 chr3:48327751 G/A cg11946769 chr3:48343235 NME6 0.74 6.34 0.49 3.97e-9 Coronary artery disease; TGCT cis rs933688 1.000 rs6867091 chr5:90734333 C/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 10.69 0.69 2.68e-19 Smoking behavior; TGCT cis rs826838 1.000 rs11169031 chr12:39056738 T/C cg26384229 chr12:38710491 ALG10B 1.01 9.58 0.65 1.31e-16 Heart rate; TGCT cis rs9916302 0.904 rs11078898 chr17:37536480 A/G cg07936489 chr17:37558343 FBXL20 0.64 4.98 0.41 2.1e-6 Glomerular filtration rate (creatinine); TGCT cis rs17711722 0.565 rs73372653 chr7:65442795 A/T cg20849893 chr7:64541193 NA 0.48 4.81 0.4 4.3e-6 Calcium levels; TGCT cis rs826838 1.000 rs10506122 chr12:38699232 A/G cg26384229 chr12:38710491 ALG10B 0.97 9.5 0.65 2.02e-16 Heart rate; TGCT cis rs7119 0.636 rs34020536 chr15:77819586 G/A cg27398640 chr15:77910606 LINGO1 -0.25 -4.55 -0.38 1.27e-5 Type 2 diabetes; TGCT cis rs10992471 0.598 rs2031262 chr9:95170368 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.63 -6.22 -0.49 6.86e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT trans rs916888 0.779 rs430685 chr17:44859148 T/C cg22433210 chr17:43662623 NA -1.0 -7.13 -0.54 7.26e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7119038 0.818 rs10892280 chr11:118611817 C/T cg19308663 chr11:118741387 NA 0.28 5.34 0.43 4.29e-7 Sjögren's syndrome; TGCT cis rs4665809 1.000 rs4665823 chr2:26312723 A/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs9527 0.615 rs7080462 chr10:104736699 T/C cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs6500602 0.610 rs1659499 chr16:4595269 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.3 -5.67 -0.45 9.66e-8 Schizophrenia; TGCT cis rs1008375 0.932 rs4698628 chr4:17608620 A/G cg10189774 chr4:17578691 LAP3 0.57 4.9 0.4 2.93e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6071524 0.508 rs911721 chr20:37399874 C/T cg09937324 chr20:37376998 ACTR5 0.61 4.69 0.39 7.22e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7829975 0.711 rs4841051 chr8:8685646 C/T cg06636001 chr8:8085503 FLJ10661 -0.71 -6.42 -0.5 2.59e-9 Mood instability; TGCT cis rs1153858 1.000 rs7169587 chr15:45640379 A/G cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs35883536 0.609 rs1855631 chr1:101040010 C/T cg06223162 chr1:101003688 GPR88 -0.43 -8.27 -0.6 1.73e-13 Monocyte count; TGCT cis rs4900538 0.928 rs1190551 chr14:102911508 A/G cg18135206 chr14:102964638 TECPR2 -0.22 -5.31 -0.43 4.81e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7172809 0.535 rs17385296 chr15:77646338 A/C cg22256960 chr15:77711686 NA -0.51 -4.81 -0.4 4.29e-6 Glucose homeostasis traits; TGCT cis rs11172134 0.508 rs1800194 chr12:57567762 C/T cg19258868 chr12:57585184 LRP1 -0.32 -6.0 -0.47 2.05e-8 Urate levels in overweight individuals; TGCT cis rs10489202 0.608 rs6659593 chr1:168072152 A/T cg24449463 chr1:168025552 DCAF6 -0.54 -5.7 -0.46 8.13e-8 Schizophrenia; TGCT cis rs2229238 0.911 rs73023339 chr1:154510852 C/T cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs12579753 0.879 rs1922552 chr12:82158093 G/T cg21231944 chr12:82153410 PPFIA2 -0.34 -4.64 -0.38 8.84e-6 Resting heart rate; TGCT cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg25151919 chr3:44754333 ZNF502 -0.47 -5.45 -0.44 2.56e-7 Depressive symptoms; TGCT cis rs9372498 0.536 rs17080292 chr6:118850266 A/G cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT cis rs2120019 0.938 rs8033925 chr15:75311959 A/G cg11632617 chr15:75315747 PPCDC -0.3 -4.44 -0.37 1.95e-5 Blood trace element (Zn levels); TGCT cis rs1903068 1.000 rs4516787 chr4:56010165 C/T cg09978860 chr4:56023921 NA -0.58 -6.64 -0.51 8.88e-10 Endometriosis; TGCT cis rs7246657 0.943 rs34603719 chr19:37794528 T/G cg18154014 chr19:37997991 ZNF793 0.91 6.21 0.49 7.22e-9 Coronary artery calcification; TGCT cis rs7666738 0.830 rs6819047 chr4:98866902 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.791 rs11040513 chr11:49778153 G/C cg15704280 chr7:45808275 SEPT13 -0.69 -8.05 -0.59 5.61e-13 Height; TGCT trans rs208520 0.661 rs207090 chr6:66783963 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.7 -0.69 2.47e-19 Exhaled nitric oxide output; TGCT cis rs2921073 0.605 rs2976933 chr8:8254875 A/G cg06636001 chr8:8085503 FLJ10661 0.51 4.58 0.38 1.12e-5 Parkinson's disease; TGCT cis rs9443645 0.687 rs6915558 chr6:79769056 A/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.555 rs1981549 chr7:99541636 A/G cg13334819 chr7:99746414 C7orf59 -0.6 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT trans rs561341 1.000 rs72825712 chr17:30316119 A/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs4820792 0.623 rs6519761 chr22:29101600 A/G cg03733026 chr22:29445468 ZNRF3 0.26 4.9 0.4 2.94e-6 Breast size; TGCT cis rs9311474 0.607 rs4475032 chr3:52560021 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.92 0.4 2.75e-6 Electroencephalogram traits; TGCT cis rs1395 1.000 rs1275522 chr2:27426878 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.5 -6.65 -0.51 8.27e-10 Blood metabolite levels; TGCT cis rs9430161 0.611 rs12081197 chr1:11034239 T/C cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs17387100 0.551 rs1517598 chr4:16020664 T/C cg13480465 chr4:16795757 LDB2 -0.42 -5.33 -0.43 4.56e-7 Suicide attempts in depression or bipolar disorder; TGCT cis rs9393692 0.645 rs766406 chr6:26319588 G/T cg00631329 chr6:26305371 NA -0.48 -7.28 -0.55 3.41e-11 Educational attainment; TGCT cis rs7714584 1.000 rs1428551 chr5:150259832 G/A cg22134413 chr5:150180641 NA 0.83 6.27 0.49 5.47e-9 Crohn's disease; TGCT cis rs1691799 0.899 rs2951656 chr12:66732273 T/G cg16791601 chr12:66731901 HELB -0.27 -5.99 -0.47 2.14e-8 White blood cell count (basophil); TGCT cis rs7043114 0.525 rs10739927 chr9:95052081 G/T cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.95e-5 Height; TGCT cis rs79349575 0.783 rs12601955 chr17:47034420 C/T cg27201301 chr17:47039149 GIP 0.25 4.47 0.37 1.72e-5 Type 2 diabetes; TGCT cis rs7044106 0.762 rs1158553 chr9:123400974 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 6.93 0.53 2.01e-10 Hip circumference adjusted for BMI; TGCT trans rs7864133 1.000 rs12377364 chr9:84103358 G/T cg23451063 chr7:1059876 C7orf50 0.62 7.18 0.54 5.76e-11 Post bronchodilator FEV1 in COPD; TGCT cis rs28595532 0.925 rs56200441 chr4:119497440 T/G cg14228332 chr4:119757509 SEC24D 1.0 5.75 0.46 6.54e-8 Cannabis dependence symptom count; TGCT cis rs10791097 0.703 rs11222360 chr11:130730871 C/T cg05962950 chr11:130786565 SNX19 0.84 10.43 0.68 1.16e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs61931739 0.500 rs11615231 chr12:34413330 T/C cg26384229 chr12:38710491 ALG10B 0.73 6.89 0.53 2.44e-10 Morning vs. evening chronotype; TGCT cis rs2688608 0.592 rs13013 chr10:75562161 C/A cg15838173 chr10:75533400 FUT11 -0.3 -4.77 -0.39 5e-6 Inflammatory bowel disease; TGCT cis rs9611565 0.608 rs2003816 chr22:42095140 T/G cg13695892 chr22:41940480 POLR3H 0.84 8.04 0.59 5.93e-13 Vitiligo; TGCT cis rs875971 1.000 rs1167612 chr7:65567976 C/A cg18876405 chr7:65276391 NA -0.34 -5.26 -0.43 6.23e-7 Aortic root size; TGCT cis rs11785400 0.793 rs10956992 chr8:143736235 A/C cg24634471 chr8:143751801 JRK 0.55 5.53 0.44 1.85e-7 Schizophrenia; TGCT cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs6121246 0.567 rs6120879 chr20:30202961 T/C cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs17253792 0.822 rs76472022 chr14:56053660 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs4727027 0.704 rs12535115 chr7:148895087 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.45 0.37 1.9e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7666738 0.830 rs7698771 chr4:98986479 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4808199 0.895 rs7252888 chr19:19628037 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.72 4.85 0.4 3.62e-6 Nonalcoholic fatty liver disease; TGCT cis rs79349575 0.749 rs318093 chr17:46989354 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.45 -0.37 1.93e-5 Type 2 diabetes; TGCT cis rs2354432 0.607 rs68080346 chr1:146708484 T/C cg25205988 chr1:146714368 CHD1L -1.15 -4.8 -0.4 4.49e-6 Mitochondrial DNA levels; TGCT cis rs11167764 1.000 rs6580220 chr5:141480558 G/A cg08523384 chr5:141488047 NDFIP1 -0.25 -5.19 -0.42 8.44e-7 Crohn's disease; TGCT cis rs2072499 0.750 rs7534339 chr1:156156219 A/G cg25208724 chr1:156163844 SLC25A44 1.0 9.15 0.63 1.46e-15 Testicular germ cell tumor; TGCT cis rs2412208 0.527 rs4436414 chr1:7120915 G/A cg20434152 chr1:7120926 CAMTA1 -0.3 -4.93 -0.4 2.56e-6 Survival in sporadic amyotrophic lateral sclerosis; TGCT cis rs6988636 1.000 rs6988636 chr8:124185970 A/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs4727027 0.727 rs1568944 chr7:148873497 A/T cg15662616 chr7:148823355 ZNF425;ZNF398 0.54 4.57 0.38 1.18e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs57221529 0.766 rs58015612 chr5:580665 A/T cg25482853 chr8:67687455 SGK3 1.17 11.24 0.71 1.19e-20 Lung disease severity in cystic fibrosis; TGCT cis rs3784262 0.669 rs3742959 chr15:58249113 A/G cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.34 -0.49 3.96e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4595586 0.545 rs1607042 chr12:39368028 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs1865760 1.000 rs9393675 chr6:25930116 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.18 0.49 8.63e-9 Height; TGCT cis rs6964587 0.872 rs57969083 chr7:91665627 A/T cg17063962 chr7:91808500 NA 0.9 9.89 0.66 2.3e-17 Breast cancer; TGCT cis rs2235649 0.561 rs12599786 chr16:1965257 T/G cg02432467 chr16:1963432 HS3ST6 -0.31 -4.59 -0.38 1.09e-5 Blood metabolite levels; TGCT trans rs1496653 0.602 rs71322173 chr3:23400823 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs56104184 0.830 rs17206679 chr19:49342237 C/G cg15549821 chr19:49342101 PLEKHA4 -0.87 -11.91 -0.73 2.81e-22 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs9560113 1.000 rs4771757 chr13:112176379 G/T cg14154082 chr13:112174009 NA 0.34 4.65 0.39 8.49e-6 Menarche (age at onset); TGCT cis rs17376456 0.877 rs13173952 chr5:93307557 A/T cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs10883723 0.810 rs61873733 chr10:104251458 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9549367 0.737 rs9549712 chr13:113902355 G/A cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs55882075 0.967 rs59666900 chr5:179147641 C/T cg14593053 chr5:179126677 CANX 0.47 4.89 0.4 3.12e-6 Monocyte percentage of white cells; TGCT cis rs10791097 0.694 rs10160281 chr11:130742788 T/C cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1552244 0.882 rs67895180 chr3:10026079 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs2832191 0.740 rs13048618 chr21:30458684 A/G cg08807101 chr21:30365312 RNF160 0.65 6.14 0.48 1.03e-8 Dental caries; TGCT cis rs1887596 0.624 rs9553861 chr13:27146449 A/G cg01312412 chr13:27282625 NA -0.27 -4.86 -0.4 3.54e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs7647973 1.000 rs4241407 chr3:49600319 C/T cg07636037 chr3:49044803 WDR6 0.65 5.35 0.43 4.01e-7 Menarche (age at onset); TGCT cis rs1008375 0.898 rs4698620 chr4:17587361 C/T cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.569 rs6002328 chr22:41710034 T/C cg13695892 chr22:41940480 POLR3H -0.64 -6.03 -0.48 1.78e-8 Vitiligo; TGCT cis rs4689592 0.583 rs12501362 chr4:7083563 C/T cg02503808 chr4:7069936 GRPEL1 -0.78 -7.39 -0.55 1.87e-11 Monocyte percentage of white cells; TGCT trans rs7613875 0.521 rs4688754 chr3:50074641 G/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.8 -8.32 -0.6 1.31e-13 Body mass index; TGCT cis rs3820068 0.655 rs59605679 chr1:15863796 T/G cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT trans rs7613875 0.578 rs2526749 chr3:50076734 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs4372836 1.000 rs11688129 chr2:28952581 T/C cg09522027 chr2:28974177 PPP1CB 0.59 5.15 0.42 1e-6 Body mass index; TGCT cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg27286337 chr10:134555280 INPP5A 0.4 4.74 0.39 5.71e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6912958 0.512 rs910563 chr6:88058885 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.71 0.46 7.78e-8 Monocyte percentage of white cells; TGCT cis rs4888262 0.526 rs8057279 chr16:74627303 C/T cg01733217 chr16:74700730 RFWD3 0.74 7.42 0.55 1.6e-11 Testicular germ cell tumor; TGCT cis rs7017914 0.967 rs1902614 chr8:71656167 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs12497850 0.931 rs6446253 chr3:48911443 C/T cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs28386778 1.000 rs3020613 chr17:61955983 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.04 0.82 5e-32 Prudent dietary pattern; TGCT cis rs17253792 0.822 rs77990307 chr14:56070049 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs10779751 1.000 rs6670821 chr1:11308762 T/C cg08854313 chr1:11322531 MTOR 0.98 9.12 0.63 1.65e-15 Body mass index; TGCT cis rs6547741 0.935 rs4260197 chr2:27794150 C/G cg27432699 chr2:27873401 GPN1 -0.19 -4.68 -0.39 7.41e-6 Oral cavity cancer; TGCT cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg02782426 chr3:40428986 ENTPD3 -0.4 -4.57 -0.38 1.15e-5 Renal cell carcinoma; TGCT cis rs2235642 0.928 rs2076435 chr16:1607574 C/T cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.47 -0.44 2.39e-7 Coronary artery disease; TGCT cis rs1577917 0.682 rs6909767 chr6:86228109 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.53 4.84 0.4 3.74e-6 Response to antipsychotic treatment; TGCT cis rs1008375 0.897 rs6820164 chr4:17630115 G/A cg18681998 chr4:17616180 MED28 1.0 10.26 0.68 2.93e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9291683 0.588 rs3733586 chr4:9997534 C/T cg11266682 chr4:10021025 SLC2A9 0.66 9.38 0.64 4.02e-16 Bone mineral density; TGCT cis rs7917772 0.503 rs11191326 chr10:104302959 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.92 -6.8 -0.52 3.96e-10 Gut microbiome composition (summer); TGCT cis rs367615 0.918 rs4576198 chr5:108867350 T/G cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs984222 0.501 rs1361906 chr1:119484644 C/T cg18199617 chr1:120311653 HMGCS2 0.19 4.5 0.37 1.57e-5 Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-hip ratio; TGCT cis rs60843830 0.661 rs11674325 chr2:105517 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.62 5.52 0.44 1.92e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10504229 0.683 rs7464038 chr8:58111908 T/C cg20607798 chr8:58055168 NA 0.56 4.66 0.39 7.88e-6 Developmental language disorder (linguistic errors); TGCT cis rs7103411 0.637 rs6416056 chr11:27646745 A/G cg10635145 chr11:27742435 BDNF -0.32 -4.56 -0.38 1.2e-5 Menarche (age at onset);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically active individuals; TGCT cis rs6866344 0.697 rs62392832 chr5:178134395 T/C cg10224037 chr5:178157518 ZNF354A 0.95 8.47 0.61 6.06e-14 Neutrophil percentage of white cells; TGCT cis rs3772130 1.000 rs17691170 chr3:121357626 G/C cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.95 0.41 2.41e-6 Cognitive performance; TGCT cis rs9926296 0.572 rs2376878 chr16:89885161 G/A cg08627397 chr16:89984028 MC1R -0.3 -4.79 -0.4 4.65e-6 Vitiligo; TGCT cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg08280861 chr8:58055591 NA 0.39 4.57 0.38 1.17e-5 Developmental language disorder (linguistic errors); TGCT cis rs2243480 1.000 rs316312 chr7:65596491 T/G cg07424592 chr7:64974309 NA 1.26 7.79 0.57 2.25e-12 Diabetic kidney disease; TGCT trans rs10435719 0.902 rs6601633 chr8:11805173 C/T cg15556689 chr8:8085844 FLJ10661 -0.73 -7.03 -0.53 1.2e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs9611565 0.592 rs8779 chr22:42070276 T/C cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Vitiligo; TGCT cis rs7666738 0.830 rs4699598 chr4:99019158 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.5 0.44 2.12e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10791097 0.547 rs10791101 chr11:130739133 C/T cg12179176 chr11:130786555 SNX19 0.85 10.17 0.67 4.79e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4372836 0.729 rs4665436 chr2:29090227 T/C cg09522027 chr2:28974177 PPP1CB 0.67 6.95 0.53 1.84e-10 Body mass index; TGCT cis rs7937682 1.000 rs10502147 chr11:111569931 G/A cg09085632 chr11:111637200 PPP2R1B 1.04 9.55 0.65 1.58e-16 Primary sclerosing cholangitis; TGCT cis rs478304 0.654 rs10896032 chr11:65459419 C/A cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.79e-13 Acne (severe); TGCT cis rs9650657 0.589 rs10107145 chr8:10758213 A/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.64 -0.38 8.87e-6 Neuroticism; TGCT cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg03452623 chr4:187889614 NA -0.34 -4.94 -0.41 2.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg18765753 chr7:1198926 ZFAND2A -0.54 -6.63 -0.51 9.33e-10 Longevity;Endometriosis; TGCT cis rs6988636 0.579 rs28528232 chr8:124189308 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9660180 0.780 rs12038111 chr1:1703849 T/C cg03396347 chr1:1875803 NA -0.36 -6.58 -0.51 1.18e-9 Body mass index; TGCT cis rs1008375 0.932 rs12500947 chr4:17603424 C/T cg16339924 chr4:17578868 LAP3 0.76 6.09 0.48 1.28e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs57221529 0.766 rs72706606 chr5:558609 T/C cg11887960 chr12:57824829 NA 1.15 9.35 0.64 4.71e-16 Lung disease severity in cystic fibrosis; TGCT cis rs875971 0.660 rs2013222 chr7:66035936 C/G cg00343986 chr7:65444356 GUSB -0.23 -5.01 -0.41 1.79e-6 Aortic root size; TGCT cis rs6860806 0.661 rs6871350 chr5:131580220 A/G cg24060327 chr5:131705240 SLC22A5 -0.55 -5.43 -0.44 2.81e-7 Breast cancer; TGCT cis rs853679 0.517 rs9393886 chr6:28050039 T/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs11190604 1.000 rs10883502 chr10:102238343 T/G cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT trans rs7819412 0.634 rs6987767 chr8:10910066 T/C cg06636001 chr8:8085503 FLJ10661 0.73 7.2 0.54 5.14e-11 Triglycerides; TGCT cis rs17221829 1.000 rs17221829 chr11:89466732 A/C cg02982614 chr11:89391479 FOLH1B 0.3 5.29 0.43 5.45e-7 Anxiety in major depressive disorder; TGCT cis rs2762353 0.595 rs12207270 chr6:25751721 A/G cg12310025 chr6:25882481 NA -0.78 -8.1 -0.59 4.37e-13 Blood metabolite levels; TGCT cis rs7772486 0.840 rs2777478 chr6:146309117 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.5 0.65 2.02e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9952991 0.566 rs514000 chr18:12854072 C/T cg23544223 chr18:12777786 NA 0.54 4.71 0.39 6.43e-6 Inflammatory skin disease; TGCT cis rs8031584 0.958 rs1043742 chr15:31232581 A/C cg08704250 chr15:31115839 NA -0.35 -4.9 -0.4 2.97e-6 Huntington's disease progression; TGCT cis rs9611565 0.546 rs739134 chr22:42089623 T/C cg03806693 chr22:41940476 POLR3H 1.06 11.74 0.73 7.15e-22 Vitiligo; TGCT cis rs763014 0.966 rs4984903 chr16:680695 A/G cg07343612 chr16:622815 PIGQ -0.42 -8.45 -0.6 6.8e-14 Height; TGCT cis rs10984561 0.881 rs57572849 chr9:122256522 T/A cg14242995 chr9:122249943 NA 0.74 6.01 0.47 1.96e-8 Pulmonary function decline; TGCT cis rs6845621 0.754 rs6820563 chr4:18887467 G/A cg12196642 chr4:18937545 NA -0.24 -4.47 -0.37 1.76e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs79149102 0.522 rs11072519 chr15:75278340 T/C cg09165964 chr15:75287851 SCAMP5 -1.08 -6.04 -0.48 1.66e-8 Lung cancer; TGCT cis rs3809566 0.613 rs16946330 chr15:63324501 C/G cg08198488 chr15:63333792 TPM1 0.32 4.68 0.39 7.3e-6 Platelet count; TGCT cis rs6987853 0.933 rs2974341 chr8:42398302 T/A cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs916888 0.779 rs199528 chr17:44843136 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.74 5.21 0.42 7.56e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs13256369 0.802 rs13256404 chr8:8562974 T/C cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs6089584 0.606 rs2144674 chr20:60576579 G/A cg06108461 chr20:60628389 TAF4 -0.4 -4.86 -0.4 3.47e-6 Body mass index; TGCT cis rs4523957 0.583 rs2984943 chr17:2030135 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9868809 0.881 rs13063312 chr3:48661985 G/A cg00383909 chr3:49044727 WDR6 0.97 5.08 0.42 1.34e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9902453 0.765 rs3102562 chr17:28040403 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.39 0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs4478858 0.735 rs1566963 chr1:31772206 G/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.03 -0.41 1.67e-6 Alcohol dependence; TGCT cis rs12887734 0.566 rs8548 chr14:104199580 A/C cg26031613 chr14:104095156 KLC1 -0.71 -5.94 -0.47 2.7e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs17030434 0.775 rs4696493 chr4:154680007 T/C cg14289246 chr4:154710475 SFRP2 0.9 7.0 0.53 1.41e-10 Electrocardiographic conduction measures; TGCT cis rs7552404 0.924 rs1858536 chr1:76161595 G/T cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10466239 0.803 rs60739384 chr10:43868029 G/A cg14116799 chr10:43800154 NA -0.56 -4.48 -0.37 1.69e-5 Telomere length; TGCT cis rs4911259 0.533 rs6058931 chr20:31471012 C/T cg13636640 chr20:31349939 DNMT3B -0.87 -9.47 -0.65 2.42e-16 Inflammatory bowel disease; TGCT cis rs7674212 0.541 rs17217473 chr4:104114742 A/C cg16532752 chr4:104119610 CENPE -0.58 -5.37 -0.43 3.66e-7 Type 2 diabetes; TGCT cis rs2730260 0.578 rs56375711 chr7:158854935 G/A cg18387198 chr7:157949267 PTPRN2 0.45 4.44 0.37 1.96e-5 Myopia (pathological); TGCT cis rs9300255 0.568 rs1727300 chr12:123664205 C/T cg00376283 chr12:123451042 ABCB9 0.72 5.61 0.45 1.27e-7 Neutrophil percentage of white cells; TGCT cis rs12701220 0.894 rs8591 chr7:1036799 C/T cg07217954 chr7:1067459 C7orf50 -0.48 -4.79 -0.39 4.76e-6 Bronchopulmonary dysplasia; TGCT cis rs4862750 0.872 rs7679956 chr4:187900229 C/T cg22105103 chr4:187893119 NA 0.33 4.67 0.39 7.83e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1568889 0.838 rs7127069 chr11:28325412 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 10.99 0.7 4.8e-20 Bipolar disorder; TGCT cis rs2456568 0.802 rs10831136 chr11:93636860 T/C cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.07e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9303401 0.659 rs17222523 chr17:56620501 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs10791097 0.748 rs4937580 chr11:130734270 T/C cg14779329 chr11:130786720 SNX19 0.29 5.12 0.42 1.16e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9810089 0.814 rs696518 chr3:136120300 A/C cg12473912 chr3:136751656 NA 0.36 5.04 0.41 1.58e-6 Gestational age at birth (child effect); TGCT cis rs916888 0.610 rs199438 chr17:44791643 G/A cg15921436 chr17:44337874 NA 0.41 6.17 0.48 8.72e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7681440 0.904 rs12331318 chr4:90770255 A/G cg14346243 chr4:90757452 SNCA -0.55 -5.36 -0.43 3.99e-7 Dementia with Lewy bodies; TGCT cis rs12220898 0.619 rs7911371 chr10:50485396 T/C cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs9640161 0.789 rs6964110 chr7:150041836 A/C cg10018233 chr7:150070692 REPIN1 0.31 4.67 0.39 7.76e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs4819052 0.851 rs8127834 chr21:46696109 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.76 0.39 5.19e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.822 rs28367231 chr4:98845726 G/T cg18180107 chr4:99064573 C4orf37 0.55 5.1 0.42 1.22e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9383153 1.000 rs9370887 chr6:16329258 G/C cg06493612 chr6:15502050 JARID2 0.59 4.74 0.39 5.7e-6 Gambling; TGCT cis rs3820068 0.581 rs6693694 chr1:15980135 G/T cg05660106 chr1:15850417 CASP9 0.79 7.46 0.56 1.29e-11 Systolic blood pressure; TGCT cis rs2070488 0.804 rs13085153 chr3:38461279 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.9 0.58 1.26e-12 Electrocardiographic conduction measures; TGCT cis rs4699052 0.963 rs6816055 chr4:104143160 T/C cg16532752 chr4:104119610 CENPE -0.58 -5.46 -0.44 2.43e-7 Testicular germ cell tumor; TGCT cis rs2268241 0.938 rs9978223 chr21:34770358 G/A cg14850771 chr21:34775459 IFNGR2 0.6 5.15 0.42 1.01e-6 Obesity-related traits; TGCT cis rs9611565 0.921 rs5751077 chr22:41720728 G/C cg17554472 chr22:41940697 POLR3H -0.39 -4.49 -0.37 1.58e-5 Vitiligo; TGCT cis rs4595586 0.545 rs11615718 chr12:39395335 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs7772486 0.764 rs2265471 chr6:146220250 G/A cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.89e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs116401323 chr4:119721727 C/T cg21605333 chr4:119757512 SEC24D 1.72 8.99 0.63 3.52e-15 Cannabis dependence symptom count; TGCT cis rs72781680 1.000 rs74704838 chr2:24158270 C/A cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs9611565 0.659 rs12483786 chr22:41938536 A/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs4595586 0.545 rs12812262 chr12:39392567 T/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs10504229 1.000 rs17216711 chr8:58170856 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg08859206 chr1:53392774 SCP2 -0.49 -7.71 -0.57 3.61e-12 Monocyte count; TGCT cis rs4862750 0.624 rs34414639 chr4:187873417 C/A cg10295955 chr4:187884368 NA -0.94 -13.14 -0.76 3.11e-25 Lobe attachment (rater-scored or self-reported); TGCT cis rs8180040 0.629 rs7426969 chr3:47091355 T/C cg27129171 chr3:47204927 SETD2 0.71 8.55 0.61 3.9e-14 Colorectal cancer; TGCT cis rs7647973 1.000 rs7613491 chr3:49508976 T/C cg07636037 chr3:49044803 WDR6 -0.73 -5.87 -0.47 3.65e-8 Menarche (age at onset); TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs3096299 0.933 rs3114848 chr16:89452771 G/A cg06640241 chr16:89574553 SPG7 0.65 6.25 0.49 6.15e-9 Multiple myeloma (IgH translocation); TGCT cis rs8064299 0.597 rs3785539 chr17:72775099 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.91 10.11 0.67 6.79e-18 Monocyte count; TGCT cis rs17387100 0.551 rs2677788 chr4:16018363 G/A cg13480465 chr4:16795757 LDB2 -0.42 -5.33 -0.43 4.56e-7 Suicide attempts in depression or bipolar disorder; TGCT cis rs7843479 0.965 rs11775479 chr8:21859991 C/T cg17168535 chr8:21777572 XPO7 0.64 5.82 0.46 4.81e-8 Mean corpuscular volume; TGCT cis rs1577917 0.740 rs6926049 chr6:86266133 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.61 5.32 0.43 4.64e-7 Response to antipsychotic treatment; TGCT cis rs7819412 0.715 rs2409727 chr8:11043236 C/T cg21775007 chr8:11205619 TDH -0.51 -4.66 -0.39 7.89e-6 Triglycerides; TGCT cis rs6695640 0.854 rs2526830 chr1:17728119 A/G cg25979543 chr1:17888104 ARHGEF10L -0.25 -4.61 -0.38 9.87e-6 Mean platelet volume; TGCT cis rs4851254 0.921 rs11679078 chr2:100757881 C/G cg23118464 chr2:100721844 AFF3 0.7 5.17 0.42 9.07e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg08677398 chr8:58056175 NA 0.35 4.7 0.39 6.72e-6 Developmental language disorder (linguistic errors); TGCT cis rs59197085 0.636 rs57072537 chr7:128435596 G/C cg00260937 chr7:128520193 KCP 0.46 4.78 0.39 4.96e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs17711722 0.522 rs62469933 chr7:65265639 G/A cg20849893 chr7:64541193 NA 0.5 5.16 0.42 9.37e-7 Calcium levels; TGCT cis rs9486719 1.000 rs2472880 chr6:96860130 G/A cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs3785574 0.962 rs4968660 chr17:61792221 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.11 14.68 0.8 6.95e-29 Height; TGCT cis rs2013441 1.000 rs2080673 chr17:20062395 C/A cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg01585852 chr22:24235823 MIF -0.22 -4.68 -0.39 7.49e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2688608 0.967 rs72814394 chr10:75656325 C/T cg23231163 chr10:75533350 FUT11 -0.25 -4.45 -0.37 1.89e-5 Inflammatory bowel disease; TGCT cis rs1691799 0.899 rs1168320 chr12:66744849 C/T cg16791601 chr12:66731901 HELB -0.28 -6.18 -0.49 8.52e-9 White blood cell count (basophil); TGCT cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs3796352 1.000 rs35849389 chr3:53005235 A/G cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9916302 0.904 rs9898170 chr17:37510092 T/C cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs72615157 0.634 rs7789890 chr7:99800559 G/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.6 -5.05 -0.41 1.54e-6 Lung function (FEV1/FVC); TGCT cis rs2692947 0.696 rs1724121 chr2:96808549 T/C cg22654517 chr2:96458247 NA 0.23 5.22 0.42 7.29e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg17554472 chr22:41940697 POLR3H 0.49 5.06 0.41 1.44e-6 Vitiligo; TGCT cis rs4665809 0.887 rs4665814 chr2:26273687 G/T cg25036284 chr2:26402008 FAM59B -0.56 -4.9 -0.4 2.88e-6 Gut microbiome composition (summer); TGCT cis rs9650657 0.515 rs6601560 chr8:10950866 T/C cg21775007 chr8:11205619 TDH -0.54 -5.03 -0.41 1.7e-6 Neuroticism; TGCT cis rs875971 1.000 rs778694 chr7:65871558 A/G cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.53e-7 Aortic root size; TGCT cis rs9357506 1.000 rs6934148 chr6:46307787 T/A cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT trans rs6089829 0.889 rs6122348 chr20:61663921 C/T cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs67311347 0.955 rs4974068 chr3:40376929 T/C cg13409248 chr3:40428643 ENTPD3 0.54 4.47 0.37 1.72e-5 Renal cell carcinoma; TGCT cis rs1215050 0.791 rs7688192 chr4:98900798 G/T cg05340658 chr4:99064831 C4orf37 -0.46 -5.82 -0.46 4.74e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10464366 0.571 rs4723825 chr7:39157627 G/C cg18850127 chr7:39170497 POU6F2 0.33 7.16 0.54 6.13e-11 IgG glycosylation; TGCT cis rs3858526 0.920 rs11511938 chr11:5928793 A/G cg05234568 chr11:5960015 NA -0.44 -4.6 -0.38 1.03e-5 DNA methylation (variation); TGCT cis rs6912958 0.559 rs376633 chr6:88042785 T/C cg10393598 chr6:87862264 NA -0.31 -4.5 -0.37 1.55e-5 Monocyte percentage of white cells; TGCT cis rs763014 0.931 rs2071982 chr16:630405 T/G cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs6760805 0.606 rs12693273 chr2:182112233 G/A cg15587571 chr2:181849325 UBE2E3 -0.3 -4.45 -0.37 1.9e-5 Lymphocyte counts; TGCT cis rs6867913 0.709 rs2338874 chr5:141466926 G/A cg01311360 chr5:140792558 PCDHGA4;PCDHGA6;PCDHGA9;PCDHGA1;PCDHGA8;PCDHGA5;PCDHGB1;PCDHGB4;PCDHGA3;PCDHGA10;PCDHGA2;PCDHGB6;PCDHGA7;PCDHGB2;PCDHGB5;PCDHGB3 -0.42 -4.84 -0.4 3.75e-6 Asthma; TGCT cis rs2657888 0.560 rs6581096 chr12:56878120 G/A cg23002907 chr12:56915593 RBMS2 -0.38 -4.78 -0.39 4.81e-6 Adiponectin levels; TGCT cis rs9993613 0.875 rs1878756 chr4:73478415 C/T cg15102770 chr4:73434591 ADAMTS3 0.49 4.72 0.39 6.34e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs6918586 0.658 rs198814 chr6:26127759 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.66 -6.22 -0.49 7.01e-9 Schizophrenia; TGCT cis rs7617480 0.648 rs9882443 chr3:48749064 G/A cg07636037 chr3:49044803 WDR6 0.77 6.25 0.49 6.14e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs1552244 0.882 rs13084194 chr3:10031492 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.22 0.49 7.14e-9 Alzheimer's disease; TGCT cis rs3820068 0.506 rs17448966 chr1:15990983 T/G cg05660106 chr1:15850417 CASP9 0.77 7.41 0.55 1.7e-11 Systolic blood pressure; TGCT cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg13607699 chr17:42295918 UBTF 0.6 5.72 0.46 7.67e-8 Total body bone mineral density; TGCT cis rs1635 0.826 rs4713159 chr6:28283772 G/A cg15743358 chr6:28303923 ZNF323 -1.34 -5.96 -0.47 2.44e-8 Schizophrenia; TGCT cis rs10466239 0.730 rs2243492 chr10:43849358 C/T cg08951903 chr10:44070173 ZNF239 -0.79 -4.91 -0.4 2.8e-6 Telomere length; TGCT cis rs1406084 0.636 rs12693841 chr2:154724818 A/C cg25703346 chr2:154729189 GALNT13 -0.77 -4.6 -0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9929218 0.559 rs55907909 chr16:68805805 C/T cg01251360 chr16:68772225 CDH1 -0.25 -4.49 -0.37 1.63e-5 Colorectal cancer; TGCT cis rs9581857 0.685 rs9579084 chr13:28028201 A/G cg22138327 chr13:27999177 GTF3A -0.7 -5.35 -0.43 4.05e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs4474465 0.850 rs10751292 chr11:78242201 C/G cg26707845 chr11:78719384 ODZ4 -0.34 -4.68 -0.39 7.39e-6 Alzheimer's disease (survival time); TGCT cis rs1153858 1.000 rs4775895 chr15:45617957 T/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.66 0.45 9.96e-8 Homoarginine levels; TGCT cis rs7226408 0.948 rs11662126 chr18:34408318 A/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs10992471 0.630 rs10453241 chr9:95198887 C/A cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -5.3 -0.43 5.16e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4478858 0.839 rs10798834 chr1:31708977 G/A cg00250761 chr1:31883323 NA -0.3 -5.66 -0.45 9.88e-8 Alcohol dependence; TGCT cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg11644478 chr21:40555479 PSMG1 0.99 10.5 0.69 7.73e-19 Cognitive function; TGCT cis rs4819052 0.819 rs8134084 chr21:46693295 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg04995860 chr1:53192072 ZYG11B -0.41 -4.48 -0.37 1.65e-5 Monocyte count; TGCT cis rs10504229 0.775 rs55764517 chr8:58158238 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs8177253 1.000 rs6439439 chr3:133481498 G/T cg01448562 chr3:133502909 NA -0.33 -6.58 -0.51 1.16e-9 Iron status biomarkers; TGCT cis rs11585357 1.000 rs11585357 chr1:17601165 C/T cg08277548 chr1:17600880 PADI3 -0.97 -9.95 -0.67 1.7e-17 Hair shape; TGCT cis rs1975974 0.511 rs113941161 chr17:21741346 T/C cg18423549 chr17:21743878 NA -0.66 -6.21 -0.49 7.18e-9 Psoriasis; TGCT cis rs13242816 1.000 rs12672236 chr7:116111369 A/G cg16553024 chr7:116138462 CAV2 0.44 4.74 0.39 5.74e-6 P wave duration; TGCT cis rs6484504 0.576 rs208091 chr11:31190099 G/C cg26647111 chr11:31128758 NA -0.34 -4.63 -0.38 9.09e-6 Red blood cell count; TGCT cis rs798554 0.759 rs1636255 chr7:2892804 A/C cg13628971 chr7:2884303 GNA12 -0.56 -4.44 -0.37 1.96e-5 Height; TGCT cis rs35934224 0.783 rs28360650 chr22:19857061 A/G cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT cis rs2235642 0.893 rs8051295 chr16:1588087 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.31 -5.42 -0.44 2.95e-7 Coronary artery disease; TGCT cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg27286337 chr10:134555280 INPP5A 0.41 5.13 0.42 1.07e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7267979 1.000 rs2482928 chr20:25331530 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs709400 0.663 rs7152202 chr14:103886757 A/G cg12935359 chr14:103987150 CKB -0.35 -5.41 -0.44 3.17e-7 Body mass index; TGCT cis rs651907 0.557 rs34457525 chr3:101435225 C/T cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.02 -0.53 1.27e-10 Colorectal cancer; TGCT cis rs10510102 0.872 rs12247367 chr10:123721071 G/A cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs9926296 0.546 rs6500442 chr16:89828862 T/C cg26513180 chr16:89883248 FANCA 1.04 14.54 0.79 1.42e-28 Vitiligo; TGCT cis rs72781680 0.898 rs17762609 chr2:24114729 G/T cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs10089 1.000 rs4835945 chr5:127526481 C/A cg19767477 chr5:127420684 SLC12A2 -0.42 -4.47 -0.37 1.77e-5 Ileal carcinoids; TGCT cis rs5769707 0.967 rs2051626 chr22:50008973 G/A cg10356904 chr22:49881777 NA -0.24 -4.81 -0.4 4.35e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg13944838 chr5:179740914 GFPT2 -0.4 -6.32 -0.49 4.35e-9 Height; TGCT cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs6831352 0.918 rs13110764 chr4:100062466 C/T cg12011299 chr4:100065546 ADH4 -0.4 -4.94 -0.41 2.51e-6 Alcohol dependence; TGCT cis rs2280018 0.526 rs2966129 chr16:15152927 A/C cg07549590 chr16:15018862 NA 0.35 5.24 0.43 6.59e-7 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9473924 0.542 rs36093098 chr6:50833931 G/A cg14470998 chr6:50812995 TFAP2B 1.33 7.94 0.58 1.05e-12 Body mass index; TGCT cis rs7267979 0.873 rs6083853 chr20:25404541 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1577917 0.771 rs9362230 chr6:86305013 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs13108904 0.539 rs13140926 chr4:1340939 G/A cg13395646 chr4:1353034 KIAA1530 -0.6 -8.06 -0.59 5.55e-13 Obesity-related traits; TGCT cis rs926938 0.618 rs360624 chr1:115409476 A/C cg12756093 chr1:115239321 AMPD1 0.41 6.19 0.49 8.06e-9 Autism; TGCT cis rs11997175 0.574 rs12541661 chr8:33649856 T/G ch.8.33884649F chr8:33765107 NA 0.28 4.53 0.38 1.35e-5 Body mass index; TGCT cis rs539096 0.874 rs2842175 chr1:44023615 G/A cg12908607 chr1:44402522 ARTN 0.55 5.51 0.44 2e-7 Intelligence (multi-trait analysis); TGCT trans rs210152 0.588 rs35817932 chr6:33457926 T/C cg08795360 chr21:41033440 B3GALT5 0.41 6.67 0.51 7.51e-10 Schizophrenia; TGCT cis rs9788721 0.802 rs56219465 chr15:78742579 A/G cg18825076 chr15:78729989 IREB2 -0.33 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs13118159 0.801 rs7690727 chr4:1340811 C/A cg22683308 chr4:1340831 KIAA1530 -0.67 -6.31 -0.49 4.6e-9 Longevity; TGCT cis rs35883536 0.609 rs2647327 chr1:101041766 C/T cg06223162 chr1:101003688 GPR88 0.42 7.93 0.58 1.11e-12 Monocyte count; TGCT cis rs2797160 0.904 rs1612274 chr6:126014907 C/A cg05901451 chr6:126070800 HEY2 0.77 6.72 0.52 5.88e-10 Endometrial cancer; TGCT cis rs7000551 0.606 rs7844699 chr8:22248920 G/T cg12081754 chr8:22256438 SLC39A14 -0.3 -4.5 -0.37 1.55e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs12048904 0.964 rs3188491 chr1:101338482 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 4.54 0.38 1.31e-5 Multiple sclerosis; TGCT cis rs78487399 0.908 rs57066469 chr2:43843813 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.58 0.38 1.12e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1153858 1.000 rs4534782 chr15:45652933 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs2980439 0.783 rs2955587 chr8:8098079 A/G cg08975724 chr8:8085496 FLJ10661 0.58 5.4 0.44 3.29e-7 Neuroticism; TGCT cis rs73198271 0.628 rs11777742 chr8:8589858 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs72945132 0.882 rs7935969 chr11:70194175 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs55883249 0.958 rs113937820 chr2:9746668 A/G cg23886495 chr2:9695866 ADAM17 0.82 5.0 0.41 1.89e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT trans rs561341 1.000 rs7214017 chr17:30332220 T/C cg20587970 chr11:113659929 NA -1.05 -12.74 -0.75 2.84e-24 Hip circumference adjusted for BMI; TGCT cis rs1348850 0.914 rs8941 chr2:178406481 C/T cg22681709 chr2:178499509 PDE11A -0.34 -4.53 -0.38 1.34e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs514475 0.526 rs9688558 chr6:137956333 G/A cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs11650494 0.908 rs73340392 chr17:47358308 G/A cg08112188 chr17:47440006 ZNF652 1.05 5.4 0.44 3.32e-7 Prostate cancer; TGCT cis rs7811142 1.000 rs7783159 chr7:100017454 C/T cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs7666738 0.830 rs7657497 chr4:99044028 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 0.652 rs76629555 chr10:102191417 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.79 0.4 4.69e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs72700829 0.576 rs6695311 chr1:151002758 G/A cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Schizophrenia; TGCT cis rs7666738 0.606 rs4637413 chr4:99088151 A/G cg17366294 chr4:99064904 C4orf37 0.57 5.34 0.43 4.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2050392 0.590 rs2065723 chr10:30720462 A/T cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT cis rs7829975 0.626 rs332040 chr8:8730488 G/A cg08975724 chr8:8085496 FLJ10661 0.57 5.27 0.43 5.92e-7 Mood instability; TGCT cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT trans rs10506458 0.915 rs998506 chr12:63400017 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT trans rs12038357 0.867 rs11802217 chr1:34963866 C/G cg06277588 chr6:13489246 GFOD1 0.52 7.09 0.54 8.88e-11 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs4820539 0.708 rs5751591 chr22:23489042 G/A cg14186256 chr22:23484241 RTDR1 0.81 8.79 0.62 1.02e-14 Bone mineral density; TGCT cis rs11674184 0.686 rs2358039 chr2:11729606 A/G cg07314298 chr2:11723111 GREB1 -0.4 -6.87 -0.53 2.77e-10 Endometriosis; TGCT cis rs174551 1 rs174551 chr11:61573684 T/C cg01500311 chr11:61656094 FADS3 -0.3 -5.25 -0.43 6.42e-7 LDL cholesterol; TGCT cis rs7552404 1.000 rs4949879 chr1:76237143 G/A cg10523679 chr1:76189770 ACADM 0.9 9.48 0.65 2.34e-16 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs7618501 0.602 rs2624853 chr3:50128893 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.87 -9.4 -0.65 3.62e-16 Intelligence (multi-trait analysis); TGCT cis rs2562456 0.917 rs2562471 chr19:21715819 C/T cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs2688608 0.901 rs2459446 chr10:75601596 C/T cg19442545 chr10:75533431 FUT11 0.3 4.54 0.38 1.29e-5 Inflammatory bowel disease; TGCT cis rs453301 0.598 rs10104303 chr8:8834528 A/T cg15556689 chr8:8085844 FLJ10661 0.72 6.53 0.51 1.52e-9 Joint mobility (Beighton score); TGCT cis rs7647973 0.961 rs4955443 chr3:49286618 T/G cg05785598 chr3:49045655 WDR6 0.39 4.61 0.38 9.91e-6 Menarche (age at onset); TGCT cis rs9560113 1.000 rs9560107 chr13:112180146 G/A cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs6545883 0.894 rs2177962 chr2:61588070 T/A cg15711740 chr2:61764176 XPO1 0.55 4.73 0.39 6.08e-6 Tuberculosis; TGCT cis rs4566648 0.553 rs7658518 chr4:84160279 C/T cg05523065 chr4:83483483 TMEM150C 0.44 4.5 0.37 1.54e-5 Monocyte count; TGCT cis rs6938 0.618 rs11072514 chr15:75221865 T/A cg09165964 chr15:75287851 SCAMP5 0.55 5.03 0.41 1.67e-6 Breast cancer; TGCT cis rs7618915 0.547 rs2590846 chr3:52692359 C/G cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs4919044 0.756 rs835257 chr10:94779801 T/A cg05127821 chr10:94822908 CYP26C1 -0.77 -5.03 -0.41 1.71e-6 Coronary artery disease; TGCT cis rs4478858 0.595 rs4949387 chr1:31803440 T/A cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs916888 0.647 rs199524 chr17:44848438 G/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.6 -4.63 -0.38 9.07e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs16867321 0.671 rs13386747 chr2:181499171 C/T cg23363182 chr2:181467187 NA -0.45 -4.71 -0.39 6.57e-6 Obesity; TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.33 0.43 4.5e-7 Prudent dietary pattern; TGCT cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg18305652 chr10:134549665 INPP5A 0.35 5.94 0.47 2.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9868809 0.505 rs11719291 chr3:48735706 A/G cg00383909 chr3:49044727 WDR6 0.98 5.67 0.45 9.63e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs2204008 0.683 rs12370288 chr12:38127740 G/A cg13010199 chr12:38710504 ALG10B 0.67 5.31 0.43 4.83e-7 Bladder cancer; TGCT cis rs6840360 0.593 rs7654294 chr4:152690975 T/C cg17479576 chr4:152424074 FAM160A1 -0.53 -5.28 -0.43 5.53e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs6500602 0.592 rs28789232 chr16:4447552 C/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.35 5.18 0.42 8.63e-7 Schizophrenia; TGCT cis rs7147624 1.000 rs7147624 chr14:65865625 G/T cg03016385 chr14:66212404 NA 0.49 7.16 0.54 6.19e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs11190604 1.000 rs11190597 chr10:102293676 A/T cg23241863 chr10:102295624 HIF1AN 0.67 5.12 0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10751667 0.643 rs10751666 chr11:941933 C/T cg06064525 chr11:970664 AP2A2 -0.34 -8.09 -0.59 4.71e-13 Alzheimer's disease (late onset); TGCT cis rs10256972 0.721 rs6975972 chr7:1070468 A/G cg16145915 chr7:1198662 ZFAND2A -0.46 -5.42 -0.44 2.96e-7 Longevity;Endometriosis; TGCT cis rs35160687 0.901 rs34048420 chr2:86529748 A/G cg12542933 chr2:85804724 VAMP8 0.41 4.9 0.4 2.97e-6 Night sleep phenotypes; TGCT cis rs8014204 0.816 rs28426374 chr14:75346740 C/T cg06637938 chr14:75390232 RPS6KL1 -0.54 -4.72 -0.39 6.15e-6 Caffeine consumption; TGCT cis rs9430161 0.645 rs12081186 chr1:11034195 T/C cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs6582630 0.555 rs4601853 chr12:38435569 G/A cg26384229 chr12:38710491 ALG10B 0.84 7.7 0.57 3.77e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg17179660 chr6:151773299 C6orf211;RMND1 -0.5 -4.59 -0.38 1.07e-5 Menarche (age at onset); TGCT cis rs9467773 1.000 rs1321479 chr6:26501897 C/T cg15659132 chr6:26577336 NA -0.84 -12.16 -0.74 7.03e-23 Intelligence (multi-trait analysis); TGCT cis rs2033711 0.503 rs7254299 chr19:58884965 A/G cg13877915 chr19:58951672 ZNF132 0.51 5.06 0.41 1.5e-6 Uric acid clearance; TGCT cis rs2456568 0.802 rs1395387 chr11:93639307 A/T cg17595323 chr11:93583763 C11orf90 -0.48 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9291683 0.632 rs10939669 chr4:10045827 A/G cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.29e-14 Bone mineral density; TGCT cis rs950169 0.845 rs4106951 chr15:84833394 C/G cg17173187 chr15:85201210 NMB 0.54 5.52 0.44 1.87e-7 Schizophrenia; TGCT cis rs6701037 0.681 rs13374887 chr1:175131962 A/T cg08873628 chr1:175162347 KIAA0040 0.48 4.67 0.39 7.58e-6 Alcohol dependence; TGCT cis rs2729354 0.779 rs2511984 chr11:57278733 T/C cg24343310 chr11:57249947 NA 0.29 4.68 0.39 7.49e-6 Blood protein levels; TGCT cis rs4629710 0.592 rs9492864 chr6:131531306 A/T cg12606694 chr6:131520996 AKAP7 0.39 4.58 0.38 1.11e-5 Multiple myeloma (IgH translocation); TGCT cis rs2718812 0.719 rs1867505 chr3:133411052 T/C cg08048268 chr3:133502702 NA 0.38 4.67 0.39 7.62e-6 Iron status biomarkers; TGCT cis rs4783244 0.526 rs11647188 chr16:82648514 A/G cg09415485 chr16:82663111 CDH13 0.25 4.58 0.38 1.13e-5 Adiponectin levels; TGCT cis rs778371 0.748 rs2675953 chr2:233749565 G/C cg25237894 chr2:233734115 C2orf82 -0.24 -4.47 -0.37 1.71e-5 Schizophrenia; TGCT cis rs10504229 0.683 rs10504225 chr8:58145121 A/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs7226408 0.857 rs57233384 chr18:34546721 A/G cg06757138 chr18:34340585 FHOD3 0.24 4.61 0.38 9.97e-6 Obesity-related traits; TGCT cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg17554472 chr22:41940697 POLR3H -0.49 -5.12 -0.42 1.11e-6 Vitiligo; TGCT cis rs807669 0.525 rs738904 chr22:19167385 C/A cg02655711 chr22:19163373 SLC25A1 0.25 4.67 0.39 7.78e-6 Metabolite levels; TGCT cis rs9486719 0.947 rs11153071 chr6:97039741 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs986417 0.818 rs10144990 chr14:60927816 T/C cg27398547 chr14:60952738 C14orf39 1.42 8.68 0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg23034840 chr1:205782522 SLC41A1 0.64 6.02 0.48 1.8e-8 Monocyte percentage of white cells; TGCT cis rs3780378 0.935 rs2149560 chr9:5082106 G/T cg03508284 chr9:4985524 JAK2 -0.47 -4.44 -0.37 1.97e-5 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1153858 1.000 rs11070456 chr15:45686835 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs17401966 0.931 rs12408430 chr1:10323339 T/A cg19773385 chr1:10388646 KIF1B -0.21 -4.55 -0.38 1.24e-5 Hepatocellular carcinoma; TGCT cis rs4819052 0.851 rs3673 chr21:46681775 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.03 0.53 1.23e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10880689 1 rs10880689 chr12:37930102 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.93 0.4 2.57e-6 Resting heart rate; TGCT cis rs7666738 0.830 rs6848404 chr4:98946750 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7949030 0.626 rs35587183 chr11:62318656 C/T cg13298116 chr11:62369859 EML3;MTA2 0.6 7.23 0.54 4.38e-11 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7659604 0.539 rs3217753 chr4:122746325 A/G cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.35 -0.43 4.15e-7 Type 2 diabetes; TGCT cis rs10791097 0.748 rs4937580 chr11:130734270 T/C cg05962950 chr11:130786565 SNX19 0.88 10.99 0.7 4.85e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs3808502 0.503 rs2061830 chr8:11397457 C/G cg15556689 chr8:8085844 FLJ10661 0.78 7.9 0.58 1.32e-12 Neuroticism; TGCT cis rs7552404 0.690 rs12723575 chr1:76335203 T/C cg03433033 chr1:76189801 ACADM -0.59 -5.97 -0.47 2.34e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs826838 0.967 rs980572 chr12:39127673 A/C cg13010199 chr12:38710504 ALG10B 0.64 5.25 0.43 6.45e-7 Heart rate; TGCT cis rs9916302 0.851 rs7225096 chr17:37664443 T/C cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs11711311 0.955 rs12636536 chr3:113474226 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs7044106 0.791 rs10984998 chr9:123481516 G/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.46 4.97 0.41 2.13e-6 Hip circumference adjusted for BMI; TGCT cis rs3733585 0.699 rs6856127 chr4:9965443 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs28595532 0.920 rs115841156 chr4:119740073 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs763014 0.932 rs35067229 chr16:649638 T/C cg27436995 chr16:743998 FBXL16 -0.47 -5.13 -0.42 1.07e-6 Height; TGCT cis rs2469997 1.000 rs2447160 chr8:120374473 G/A cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs79387448 0.745 rs17027341 chr2:103136559 A/G cg09003973 chr2:102972529 NA 0.81 5.21 0.42 7.75e-7 Gut microbiota (bacterial taxa); TGCT cis rs1577917 1.000 rs12216328 chr6:86703418 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs10504229 1.000 rs68112919 chr8:58188247 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2760061 0.583 rs1745413 chr1:228212456 A/G cg18477163 chr1:228402036 OBSCN 0.34 7.06 0.54 1.04e-10 Diastolic blood pressure; TGCT cis rs12497850 0.931 rs4974087 chr3:48919232 A/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs950880 0.560 rs10189202 chr2:102930380 A/G cg09003973 chr2:102972529 NA -0.51 -4.49 -0.37 1.59e-5 Serum protein levels (sST2); TGCT cis rs910316 0.967 rs11624893 chr14:75660124 A/G cg11812906 chr14:75593930 NEK9 -0.72 -6.79 -0.52 4.14e-10 Height; TGCT cis rs926938 0.563 rs360645 chr1:115427218 A/G cg12756093 chr1:115239321 AMPD1 0.4 6.31 0.49 4.55e-9 Autism; TGCT trans rs4919669 0.668 rs17114810 chr10:104391545 C/T cg24066601 chr6:26271455 HIST1H3G 0.68 6.69 0.51 7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs881375 0.715 rs10818482 chr9:123648085 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 -0.4 -4.56 -0.38 1.23e-5 Rheumatoid arthritis; TGCT cis rs711245 0.518 rs11886145 chr2:36825716 C/G cg09467607 chr2:36825704 FEZ2 0.37 5.81 0.46 5.01e-8 Height; TGCT cis rs13108904 0.837 rs4591539 chr4:1279938 G/C cg05665937 chr4:1216051 CTBP1 0.24 4.47 0.37 1.72e-5 Obesity-related traits; TGCT cis rs5769765 0.955 rs5769767 chr22:50276909 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs11098499 0.874 rs12509054 chr4:120115075 A/C cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs9916302 0.706 rs4287601 chr17:37513852 T/C cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs3087591 0.708 rs964288 chr17:29679246 G/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.52 0.44 1.87e-7 Hip circumference; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg10263370 chr3:44754102 ZNF502 -0.44 -5.25 -0.43 6.37e-7 Depressive symptoms; TGCT cis rs4455778 0.626 rs6583485 chr7:49014353 A/G cg26309511 chr7:48887640 NA -0.45 -5.56 -0.45 1.6e-7 Lung cancer in never smokers; TGCT cis rs9303401 0.538 rs2240258 chr17:56458183 C/A cg25039879 chr17:56429692 SUPT4H1 0.61 5.25 0.43 6.47e-7 Cognitive test performance; TGCT cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg08280861 chr8:58055591 NA 0.5 5.52 0.44 1.93e-7 Developmental language disorder (linguistic errors); TGCT cis rs899997 1.000 rs11072800 chr15:79045857 C/T cg04896959 chr15:78267971 NA -0.3 -4.46 -0.37 1.79e-5 Coronary artery disease or large artery stroke; TGCT cis rs75565482 0.546 rs12091766 chr1:168463133 A/G cg09922481 chr1:168698463 DPT 0.54 4.51 0.38 1.45e-5 Emphysema imaging phenotypes; TGCT cis rs4788570 0.667 rs9929840 chr16:71800942 C/T cg06353428 chr16:71660113 MARVELD3 -1.57 -11.92 -0.73 2.63e-22 Intelligence (multi-trait analysis); TGCT cis rs7010267 0.740 rs6993910 chr8:119950781 C/T cg17171407 chr8:119960777 TNFRSF11B -0.25 -4.44 -0.37 2e-5 Total body bone mineral density (age 45-60); TGCT cis rs9928842 0.770 rs8048371 chr16:75275547 C/T cg09066997 chr16:75300724 BCAR1 0.27 4.79 0.39 4.72e-6 Alcoholic chronic pancreatitis; TGCT cis rs9611565 0.546 rs34077262 chr22:42061639 A/G cg13695892 chr22:41940480 POLR3H 0.8 7.59 0.56 6.62e-12 Vitiligo; TGCT cis rs9611565 0.570 rs12159188 chr22:42121125 A/T cg17554472 chr22:41940697 POLR3H 0.46 5.0 0.41 1.91e-6 Vitiligo; TGCT cis rs7211079 0.505 rs60323863 chr17:78125086 A/G cg09238746 chr17:78121135 EIF4A3 -0.76 -5.2 -0.42 7.86e-7 Myocardial infarction; TGCT cis rs7666738 0.830 rs6831219 chr4:98993576 C/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.690 rs552517 chr11:68625286 T/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 7.55 0.56 8.19e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9311474 1.000 rs2276834 chr3:52325759 A/G cg07507251 chr3:52567010 NT5DC2 0.46 6.21 0.49 7.16e-9 Electroencephalogram traits; TGCT cis rs10992471 0.528 rs1924244 chr9:95224952 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.52 -4.91 -0.4 2.8e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4918072 0.667 rs11191874 chr10:105711107 T/C cg11005552 chr10:105648138 OBFC1 0.33 4.6 0.38 1.03e-5 Coronary artery disease; TGCT cis rs9894429 0.646 rs7406828 chr17:79619226 A/G cg21028142 chr17:79581711 NPLOC4 -0.29 -6.07 -0.48 1.45e-8 Eye color traits; TGCT trans rs561341 0.739 rs6505267 chr17:30225950 A/C cg20587970 chr11:113659929 NA -0.65 -9.12 -0.63 1.65e-15 Hip circumference adjusted for BMI; TGCT cis rs7246657 0.943 rs4801803 chr19:37966923 A/G cg18154014 chr19:37997991 ZNF793 -0.95 -6.63 -0.51 9.39e-10 Coronary artery calcification; TGCT cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg17554472 chr22:41940697 POLR3H 0.47 4.91 0.4 2.87e-6 Vitiligo; TGCT cis rs765787 0.530 rs12440238 chr15:45512905 T/C cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs72945132 0.769 rs680571 chr11:70187441 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs904251 0.523 rs2797794 chr6:37480604 T/C cg25019722 chr6:37503610 NA -0.53 -7.98 -0.58 8.18e-13 Cognitive performance; TGCT cis rs9328448 1.000 rs2326980 chr6:7990901 A/G cg13863638 chr6:7199401 RREB1 0.19 4.57 0.38 1.15e-5 Coronary artery calcification; TGCT cis rs7568458 0.870 rs6733913 chr2:85757379 T/C cg17127132 chr2:85788382 GGCX 0.72 6.69 0.51 6.94e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs478304 0.900 rs502468 chr11:65525119 T/G cg27068330 chr11:65405492 SIPA1 0.75 7.57 0.56 7.2e-12 Acne (severe); TGCT cis rs9902453 0.845 rs3115101 chr17:28041627 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs4713118 0.629 rs172165 chr6:28020814 T/G cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs2188554 0.958 rs73480753 chr7:117027181 C/T cg09181792 chr7:117119393 CFTR 0.51 4.43 0.37 2.01e-5 Esophageal adenocarcinoma; TGCT cis rs9467773 0.565 rs6925047 chr6:26521435 C/G cg15659132 chr6:26577336 NA 0.73 9.04 0.63 2.64e-15 Intelligence (multi-trait analysis); TGCT cis rs4727027 0.933 rs4727028 chr7:148874666 A/G cg23583168 chr7:148888333 NA 0.72 9.42 0.65 3.26e-16 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs796364 0.906 rs281789 chr2:200780698 T/G cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs9660992 0.573 rs12126439 chr1:205200720 C/T cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs11098499 0.866 rs3756156 chr4:120524841 G/A cg09307838 chr4:120376055 NA 0.67 6.29 0.49 5.06e-9 Corneal astigmatism; TGCT cis rs7178572 1.000 rs8034133 chr15:77763712 C/G cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs3806933 0.522 rs13179305 chr5:110444474 G/A cg04022379 chr5:110408740 TSLP 0.58 6.0 0.47 1.97e-8 Eosinophilic esophagitis; TGCT cis rs2692947 0.683 rs62153700 chr2:96581338 C/T cg23100626 chr2:96804247 ASTL 0.5 5.9 0.47 3.24e-8 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg20887711 chr4:1340912 KIAA1530 0.91 7.95 0.58 1e-12 Longevity; TGCT cis rs916888 0.610 rs199452 chr17:44801340 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.59 4.61 0.38 9.8200000000000008e-06 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7267979 1.000 rs2257809 chr20:25266476 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1878931 0.597 rs2680221 chr16:3462595 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.71 -5.62 -0.45 1.18e-7 Body mass index (adult); TGCT cis rs7043114 0.525 rs10116241 chr9:95240546 T/C cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.98e-5 Height; TGCT cis rs1865760 0.566 rs9379825 chr6:26083871 C/A cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs9303401 0.659 rs34426768 chr17:56683385 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs6121246 0.529 rs6060144 chr20:30178624 A/G cg18721089 chr20:30220636 NA -0.63 -6.68 -0.51 7.29e-10 Mean corpuscular hemoglobin; TGCT cis rs1712517 0.524 rs4917384 chr10:104995788 T/C cg04362960 chr10:104952993 NT5C2 0.59 4.66 0.39 7.89e-6 Migraine; TGCT cis rs7020830 0.898 rs308523 chr9:37338785 C/T cg14294708 chr9:37120828 ZCCHC7 1.11 14.41 0.79 2.97e-28 Schizophrenia; TGCT cis rs10504229 0.683 rs2101864 chr8:58113226 C/T cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs427394 0.796 rs274683 chr5:6747950 T/A cg10857441 chr5:6722123 POLS -0.23 -4.98 -0.41 2.11e-6 Menopause (age at onset); TGCT cis rs1372520 0.873 rs983361 chr4:90761944 T/G cg26578617 chr4:90757533 SNCA -0.5 -4.52 -0.38 1.42e-5 Neuroticism; TGCT cis rs9346649 0.967 rs6915427 chr6:168490000 A/T cg02770688 chr6:168491649 NA 0.27 5.08 0.41 1.36e-6 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 -0.52 -5.54 -0.45 1.74e-7 Lymphocyte counts; TGCT cis rs2963155 0.518 rs852978 chr5:142690596 T/C cg17617527 chr5:142782415 NR3C1 0.85 6.31 0.49 4.42e-9 Breast cancer; TGCT cis rs734999 0.566 rs6664969 chr1:2534978 G/A cg18854424 chr1:2615690 NA 0.43 4.96 0.41 2.31e-6 Ulcerative colitis; TGCT cis rs78487399 0.908 rs12467151 chr2:43813764 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs26868 0.742 rs26848 chr16:2263516 A/G cg11648456 chr16:2261069 C16orf79 -0.26 -5.18 -0.42 8.64e-7 Height; TGCT cis rs11785400 0.793 rs4430070 chr8:143729184 G/C cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.79e-7 Schizophrenia; TGCT cis rs62244186 0.606 rs6798590 chr3:44556861 T/A cg02073558 chr3:44770973 ZNF501 0.66 6.19 0.49 8.13e-9 Depressive symptoms; TGCT cis rs13108904 0.935 rs11247984 chr4:1292811 G/A cg00684032 chr4:1343700 KIAA1530 0.23 5.01 0.41 1.79e-6 Obesity-related traits; TGCT cis rs6570726 0.791 rs6902404 chr6:145905254 G/A cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs916888 0.821 rs199504 chr17:44861003 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.72 -4.93 -0.4 2.57e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs804280 0.505 rs804271 chr8:11627214 C/A cg26752888 chr8:11627280 NEIL2 -0.57 -5.26 -0.43 6.15e-7 Myopia (pathological); TGCT cis rs28386778 0.897 rs968719 chr17:61908271 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.53 4.76 0.39 5.37e-6 Prudent dietary pattern; TGCT cis rs7949030 0.591 rs11231156 chr11:62366454 G/A cg22862634 chr11:62369728 EML3;MTA2 0.7 8.89 0.62 5.98e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs644799 0.542 rs10831418 chr11:95468828 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.6 5.9 0.47 3.17e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9790314 0.905 rs7611367 chr3:161003182 A/G cg03342759 chr3:160939853 NMD3 0.41 4.51 0.38 1.51e-5 Morning vs. evening chronotype; TGCT cis rs77972916 0.561 rs10167415 chr2:43552460 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.81 -0.46 4.84e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs9914988 0.943 rs28847895 chr17:27172520 T/C cg20469991 chr17:27169893 C17orf63 -0.68 -5.01 -0.41 1.87e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1008375 0.966 rs1860591 chr4:17577329 A/G cg18681998 chr4:17616180 MED28 0.88 9.23 0.64 9.32e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12477438 0.798 rs10202452 chr2:99569409 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.28 -0.49 5.3e-9 Chronic sinus infection; TGCT cis rs9868809 0.881 rs2286652 chr3:48689192 G/A cg07636037 chr3:49044803 WDR6 -0.88 -4.54 -0.38 1.32e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs2334880 0.610 rs8051767 chr16:71731720 C/T cg06353428 chr16:71660113 MARVELD3 1.56 12.9 0.76 1.14e-24 Malaria; TGCT cis rs514406 0.763 rs6685599 chr1:53213172 G/A cg08736216 chr1:53307985 ZYG11A 0.25 4.77 0.39 4.98e-6 Monocyte count; TGCT cis rs1125355 0.690 rs1356173 chr2:159651973 G/A cg21992932 chr2:159651813 DAPL1 -0.23 -4.43 -0.37 2.01e-5 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs8073060 0.614 rs225279 chr17:33974214 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7172809 0.643 rs80347838 chr15:77841783 A/G cg22256960 chr15:77711686 NA -0.48 -4.84 -0.4 3.84e-6 Glucose homeostasis traits; TGCT cis rs4319547 0.586 rs7956480 chr12:122817507 A/G cg08088222 chr12:122070432 ORAI1 0.27 4.78 0.39 4.94e-6 Body mass index; TGCT cis rs10927875 0.526 rs35340817 chr1:16178917 T/C cg21385522 chr1:16154831 NA -0.91 -9.29 -0.64 6.69e-16 Dilated cardiomyopathy; TGCT cis rs7772486 0.790 rs9497431 chr6:146248177 T/C cg23711669 chr6:146136114 FBXO30 -0.88 -10.27 -0.68 2.84e-18 Lobe attachment (rater-scored or self-reported); TGCT trans rs561341 0.941 rs7215147 chr17:30266711 G/A cg20587970 chr11:113659929 NA -0.95 -10.83 -0.7 1.21e-19 Hip circumference adjusted for BMI; TGCT cis rs7584330 0.868 rs2325839 chr2:238386286 T/C cg14458575 chr2:238380390 NA 0.55 8.27 0.6 1.78e-13 Prostate cancer; TGCT cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg13395646 chr4:1353034 KIAA1530 -0.38 -4.72 -0.39 6.28e-6 Obesity-related traits; TGCT trans rs66573146 0.831 rs67602077 chr4:7024244 A/G cg07817883 chr1:32538562 TMEM39B 1.7 8.44 0.6 7.06e-14 Granulocyte percentage of myeloid white cells; TGCT cis rs453301 0.631 rs28572014 chr8:8793607 C/T cg15556689 chr8:8085844 FLJ10661 -0.63 -5.37 -0.43 3.82e-7 Joint mobility (Beighton score); TGCT cis rs3784262 0.542 rs2899611 chr15:58327347 A/C cg12031962 chr15:58353849 ALDH1A2 -0.39 -5.84 -0.46 4.33e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6840360 0.593 rs59350867 chr4:152695935 G/A cg17479576 chr4:152424074 FAM160A1 -0.53 -5.26 -0.43 5.99e-7 Intelligence (multi-trait analysis); TGCT cis rs6671200 0.920 rs259350 chr1:95724831 G/C cg26537280 chr1:95699037 RWDD3 -0.7 -5.55 -0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs12908161 1.000 rs12912388 chr15:85344550 T/A cg12863693 chr15:85201151 NMB 0.42 5.06 0.41 1.5e-6 Schizophrenia; TGCT cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 4.92 0.4 2.73e-6 Schizophrenia; TGCT cis rs1153858 1.000 rs1145074 chr15:45703824 T/A cg26924012 chr15:45694286 SPATA5L1 0.98 12.23 0.74 4.72e-23 Homoarginine levels; TGCT cis rs35146811 0.735 rs1637001 chr7:99808151 G/A cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs6074578 0.535 rs1858592 chr20:138606 A/G cg16931068 chr20:139680 DEFB127 0.28 4.56 0.38 1.21e-5 Hirschsprung disease; TGCT cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs7592578 0.713 rs60915953 chr2:191331304 G/C cg11845111 chr2:191398756 TMEM194B -0.41 -4.54 -0.38 1.32e-5 Diastolic blood pressure; TGCT cis rs2439831 0.867 rs2447196 chr15:43893818 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.89 -6.57 -0.51 1.25e-9 Lung cancer in ever smokers; TGCT cis rs2832191 0.791 rs7283853 chr21:30498515 G/A cg24692254 chr21:30365293 RNF160 -0.86 -9.11 -0.63 1.83e-15 Dental caries; TGCT cis rs7191439 0.674 rs4782430 chr16:88792047 A/G cg27087555 chr16:88793112 FAM38A -0.41 -5.56 -0.45 1.57e-7 Plateletcrit; TGCT cis rs11264213 0.591 rs3754076 chr1:36549157 A/G cg27506609 chr1:36549197 TEKT2 -0.4 -6.54 -0.51 1.48e-9 Schizophrenia; TGCT cis rs7267979 0.586 rs6037057 chr20:25182089 T/C cg16686733 chr20:25566563 NINL 0.53 5.43 0.44 2.9e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs523522 0.962 rs12309824 chr12:120990582 A/C cg12219531 chr12:120966889 COQ5 0.8 7.15 0.54 6.6e-11 High light scatter reticulocyte count; TGCT cis rs3749237 1.000 rs11920900 chr3:49823024 G/C cg03060546 chr3:49711283 APEH 0.73 7.58 0.56 7.07e-12 Resting heart rate; TGCT cis rs9308731 1.000 rs1980045 chr2:111904541 A/G cg04202892 chr2:111875749 ACOXL 0.43 4.45 0.37 1.92e-5 Chronic lymphocytic leukemia; TGCT cis rs11030122 0.632 rs7925954 chr11:3982746 A/T cg18678763 chr11:4115507 RRM1 -0.41 -5.09 -0.42 1.27e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs877282 1.000 rs877281 chr10:771557 T/G cg17470449 chr10:769945 NA 0.31 4.77 0.39 5.04e-6 Uric acid levels; TGCT trans rs7618501 1.000 rs4855862 chr3:49748833 C/T cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs2188554 1.000 rs2188554 chr7:117040117 A/G cg09181792 chr7:117119393 CFTR 0.51 4.57 0.38 1.15e-5 Esophageal adenocarcinoma; TGCT cis rs1061377 1.000 rs7675782 chr4:39121668 G/A cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.43 -0.44 2.84e-7 Coronary artery disease; TGCT cis rs7845219 0.544 rs9643351 chr8:95917290 C/T cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs986417 1.000 rs2144114 chr14:61064210 T/C cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs7824557 0.564 rs2572389 chr8:11236392 T/C cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs10782582 0.545 rs12138018 chr1:76186794 T/C cg03433033 chr1:76189801 ACADM -0.62 -6.81 -0.52 3.69e-10 Daytime sleep phenotypes; TGCT cis rs617219 0.726 rs1275105 chr5:78444148 T/C cg23987322 chr5:78407566 BHMT 0.35 4.68 0.39 7.3e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2034088 0.591 rs4968166 chr17:404537 C/T cg04370829 chr17:406249 NA -0.36 -5.26 -0.43 6.01e-7 Hip circumference adjusted for BMI; TGCT cis rs2841277 0.708 rs9671643 chr14:105408030 A/G cg21017887 chr14:105400489 NA 0.36 5.14 0.42 1.04e-6 Rheumatoid arthritis; TGCT cis rs11096990 0.593 rs7685619 chr4:39213399 T/G cg20847110 chr4:39482781 LOC401127 0.16 4.58 0.38 1.13e-5 Cognitive function; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg12419862 chr22:24373484 LOC391322 0.87 10.28 0.68 2.65e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2404602 0.692 rs12594556 chr15:77165363 G/A cg26408565 chr15:76604113 ETFA -0.36 -4.52 -0.38 1.41e-5 Blood metabolite levels; TGCT cis rs796364 0.806 rs1605900 chr2:200870197 C/G cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT cis rs11249608 0.548 rs11960161 chr5:178453837 A/G cg23951258 chr5:178450506 ZNF879 0.45 4.61 0.38 9.7e-6 Pubertal anthropometrics; TGCT cis rs116095464 0.558 rs6878061 chr5:223072 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs6722750 0.651 rs2901646 chr2:64414892 A/G cg22352474 chr2:64371530 PELI1 0.51 4.52 0.38 1.45e-5 Neuroticism; TGCT cis rs6952808 0.723 rs11765550 chr7:2027324 G/A cg22963979 chr7:1858916 MAD1L1 -0.45 -7.4 -0.55 1.76e-11 Bipolar disorder and schizophrenia; TGCT cis rs56104184 0.775 rs55981795 chr19:49401952 A/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT trans rs10506458 0.915 rs17687426 chr12:63397900 G/C cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs2147959 0.941 rs7524236 chr1:228630395 C/T cg22700015 chr1:228743131 NA 0.56 4.45 0.37 1.91e-5 Adult asthma; TGCT cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs57994353 0.897 rs72775772 chr9:139356738 C/T cg13741927 chr9:139327495 INPP5E -0.26 -6.0 -0.47 2.05e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9611565 0.592 rs4822040 chr22:41963553 C/G cg17554472 chr22:41940697 POLR3H -0.45 -4.73 -0.39 5.94e-6 Vitiligo; TGCT cis rs259282 0.605 rs28615461 chr19:33110149 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.54 4.91 0.4 2.76e-6 Schizophrenia; TGCT cis rs853679 0.550 rs1150692 chr6:28173957 A/G cg12963246 chr6:28129442 ZNF389 0.5 4.88 0.4 3.15e-6 Depression; TGCT cis rs4862750 0.832 rs4862744 chr4:187877074 T/A cg11301795 chr4:187892539 NA -0.32 -4.72 -0.39 6.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2046867 0.628 rs7617996 chr3:72915315 C/T cg25664220 chr3:72788482 NA -0.41 -5.67 -0.45 9.38e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4665809 0.938 rs35844686 chr2:26304949 A/G cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 3e-8 Gut microbiome composition (summer); TGCT cis rs911555 1.000 rs2756127 chr14:104000183 C/T cg12935359 chr14:103987150 CKB 0.35 4.99 0.41 2.03e-6 Intelligence (multi-trait analysis); TGCT cis rs16957091 0.647 rs16957422 chr15:43393646 G/A cg17935677 chr15:44119062 WDR76 0.56 4.73 0.39 5.94e-6 MGMT methylation in smokers; TGCT cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2832191 0.636 rs8131295 chr21:30516819 A/T cg24692254 chr21:30365293 RNF160 -0.61 -5.38 -0.43 3.62e-7 Dental caries; TGCT trans rs2469997 1.000 rs2470008 chr8:120359366 C/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs8180040 0.966 rs2291298 chr3:47555142 C/A cg27129171 chr3:47204927 SETD2 0.62 7.34 0.55 2.41e-11 Colorectal cancer; TGCT cis rs72615157 0.634 rs74774557 chr7:99810425 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.74 5.77 0.46 6e-8 Lung function (FEV1/FVC); TGCT cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs12541335 0.692 rs2290274 chr8:22214374 C/T cg09517075 chr8:22133004 PIWIL2 0.25 4.96 0.41 2.29e-6 Hypertriglyceridemia; TGCT cis rs751728 1.000 rs1359781 chr6:33762104 T/C cg13859433 chr6:33739653 LEMD2 -0.39 -7.08 -0.54 9.45e-11 Crohn's disease; TGCT cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg17971929 chr21:40555470 PSMG1 0.67 6.26 0.49 5.74e-9 Cognitive function; TGCT cis rs12902680 0.739 rs28894739 chr15:46420019 G/A cg13605988 chr15:45421612 DUOX1;DUOXA1 0.32 4.52 0.38 1.4e-5 Neuroticism; TGCT cis rs2921073 0.510 rs2976945 chr8:8270871 G/T cg06636001 chr8:8085503 FLJ10661 0.65 5.45 0.44 2.59e-7 Parkinson's disease; TGCT cis rs4076764 0.914 rs10753614 chr1:163365903 C/T cg24596788 chr1:163392923 NA 0.17 4.9 0.4 2.99e-6 Motion sickness; TGCT cis rs2882877 0.648 rs35000023 chr2:190375710 G/T cg10752008 chr2:190445175 SLC40A1 0.61 4.48 0.37 1.68e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs174479 0.647 rs174461 chr11:61657401 A/C cg01500311 chr11:61656094 FADS3 0.28 5.03 0.41 1.68e-6 Sphingolipid levels; TGCT cis rs603446 1.000 rs603446 chr11:116654435 C/T cg20608306 chr11:116969690 SIK3 0.41 4.74 0.39 5.85e-6 Triglycerides; TGCT cis rs5769707 0.732 rs135865 chr22:50004829 G/A cg05373962 chr22:49881684 NA -0.31 -5.97 -0.47 2.34e-8 Monocyte count;Monocyte percentage of white cells; TGCT trans rs1814175 0.817 rs2866545 chr11:49630824 A/C cg11707556 chr5:10655725 ANKRD33B -0.38 -7.57 -0.56 7.52e-12 Height; TGCT cis rs1008375 1.000 rs6811887 chr4:17640858 C/T cg18681998 chr4:17616180 MED28 1.0 11.93 0.73 2.54e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6570726 0.693 rs450921 chr6:145864260 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs13121558 chr4:99002848 G/A cg05340658 chr4:99064831 C4orf37 0.47 5.19 0.42 8.29e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9894429 0.752 rs7502883 chr17:79588557 T/C cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.1e-17 Eye color traits; TGCT cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs926938 0.527 rs11084 chr1:115537933 A/G cg12756093 chr1:115239321 AMPD1 0.34 4.97 0.41 2.19e-6 Autism; TGCT cis rs12643440 0.538 rs62296683 chr4:17137441 C/G cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs9905704 0.647 rs2036730 chr17:57038282 A/G cg05425664 chr17:57184151 TRIM37 -0.6 -4.75 -0.39 5.47e-6 Testicular germ cell tumor; TGCT cis rs7523273 0.606 rs2488252 chr1:207938228 C/T cg22525895 chr1:207977042 MIR29B2 0.53 8.71 0.62 1.62e-14 Schizophrenia; TGCT cis rs11105298 0.891 rs10858899 chr12:89923811 G/C cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs66573146 1.000 rs7675281 chr4:7002120 C/T cg05069807 chr4:6945702 TBC1D14 0.38 5.12 0.42 1.11e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs4233949 0.897 rs6752877 chr2:54661569 A/C cg14634210 chr2:54682758 SPTBN1 -0.58 -4.83 -0.4 3.9e-6 Bone mineral density; TGCT cis rs10504229 0.906 rs56138544 chr8:58184558 A/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs3782455 0.793 rs2290801 chr12:114404424 C/G cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1887596 0.588 rs523019 chr13:27109968 A/T cg01312412 chr13:27282625 NA -0.26 -4.49 -0.37 1.62e-5 Facial morphology (factor 3, length of philtrum); TGCT cis rs9921222 0.509 rs3743883 chr16:404750 T/C cg00101154 chr16:420108 MRPL28 -0.55 -5.67 -0.45 9.41e-8 Bone mineral density (spine);Bone mineral density; TGCT cis rs346785 0.965 rs443970 chr17:74303370 G/A cg09812376 chr17:74270190 QRICH2 -0.39 -5.72 -0.46 7.49e-8 White matter hyperintensities in ischemic stroke; TGCT cis rs7829975 0.742 rs7832968 chr8:8652889 G/A cg06636001 chr8:8085503 FLJ10661 0.68 5.95 0.47 2.61e-8 Mood instability; TGCT cis rs9611565 0.512 rs6002474 chr22:42168181 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT trans rs4332037 1.000 rs62442899 chr7:1948454 C/T cg25206134 chr2:45395956 NA 1.11 9.39 0.64 3.79e-16 Bipolar disorder; TGCT cis rs7954584 0.813 rs12827200 chr12:122451278 G/A cg21171335 chr12:122356390 WDR66 0.55 5.34 0.43 4.21e-7 Mean corpuscular volume; TGCT cis rs9611565 0.644 rs2413652 chr22:42097238 C/T cg03806693 chr22:41940476 POLR3H 0.97 9.76 0.66 4.74e-17 Vitiligo; TGCT cis rs2535633 0.631 rs2710346 chr3:52974152 C/T cg11645453 chr3:52864694 ITIH4 -0.28 -5.05 -0.41 1.54e-6 Body mass index; TGCT cis rs28595532 0.841 rs115924581 chr4:119786333 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs42648 0.905 rs42622 chr7:89956824 A/G cg25739043 chr7:89950458 NA -0.75 -7.62 -0.56 5.63e-12 Homocysteine levels; TGCT cis rs11948739 0.537 rs12518203 chr5:130233745 G/A cg08523029 chr5:130500466 HINT1 -0.59 -4.93 -0.4 2.58e-6 Pediatric bone mineral content (hip); TGCT cis rs7666738 0.830 rs34070283 chr4:98893027 A/T cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.81e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6545977 0.531 rs2539982 chr2:63111004 G/A cg17519650 chr2:63277830 OTX1 0.72 7.2 0.54 5.17e-11 Prostate cancer; TGCT cis rs6490294 0.651 rs440 chr12:112228714 T/C cg10833066 chr12:111807467 FAM109A 0.37 4.72 0.39 6.22e-6 Mean platelet volume; TGCT cis rs3087591 1.000 rs9902893 chr17:29625638 G/A cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.51 -0.56 1.01e-11 Hip circumference; TGCT cis rs7264396 0.790 rs6058297 chr20:34271861 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs9926296 0.632 rs4785717 chr16:89801133 A/G cg08627397 chr16:89984028 MC1R -0.32 -5.18 -0.42 8.68e-7 Vitiligo; TGCT cis rs7769051 1.000 rs9493445 chr6:133125409 C/T cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs10782582 0.609 rs1796810 chr1:76403305 C/T cg03433033 chr1:76189801 ACADM -0.52 -5.06 -0.41 1.44e-6 Daytime sleep phenotypes; TGCT cis rs1865760 0.663 rs9348704 chr6:26000393 A/C cg16482183 chr6:26056742 HIST1H1C 0.57 5.13 0.42 1.08e-6 Height; TGCT cis rs10465746 0.967 rs10493744 chr1:84444752 C/T cg10977910 chr1:84465055 TTLL7 -0.63 -6.23 -0.49 6.49e-9 Obesity-related traits; TGCT cis rs11969893 0.850 rs9498409 chr6:101299966 G/A cg12253828 chr6:101329408 ASCC3 1.36 6.32 0.49 4.33e-9 Economic and political preferences (immigration/crime); TGCT cis rs265548 0.595 rs265543 chr19:17904260 T/G cg04517722 chr19:17905589 B3GNT3 0.46 5.96 0.47 2.42e-8 Tumor biomarkers; TGCT cis rs910316 0.687 rs175059 chr14:75490667 T/C cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.36e-7 Height; TGCT cis rs12497850 0.931 rs7430501 chr3:48890119 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg11905131 chr22:24372483 LOC391322 -0.95 -11.19 -0.71 1.64e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs317689 0.718 rs315122 chr12:69771073 G/T cg14784868 chr12:69753453 YEATS4 0.54 4.58 0.38 1.11e-5 Response to diuretic therapy; TGCT cis rs6582630 0.623 rs12299293 chr12:38436288 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6951245 0.554 rs79367977 chr7:1152657 G/A cg09177884 chr7:1199841 ZFAND2A -0.69 -5.47 -0.44 2.41e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs6089584 0.861 rs2180302 chr20:60576369 A/G cg13770153 chr20:60521292 NA -0.55 -7.02 -0.53 1.27e-10 Body mass index; TGCT cis rs12367572 0.930 rs10880695 chr12:45233261 T/C cg04608330 chr12:45269318 NELL2 -0.5 -4.68 -0.39 7.33e-6 Gut microbiome composition (summer); TGCT cis rs67311347 0.544 rs7652439 chr3:40349948 G/T cg13683864 chr3:40499215 RPL14 -0.76 -6.62 -0.51 9.6e-10 Renal cell carcinoma; TGCT cis rs6940638 0.662 rs7759694 chr6:27240956 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.43 -4.55 -0.38 1.28e-5 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.632 rs1328919 chr9:5166548 C/T cg02405213 chr9:5042618 JAK2 -0.74 -9.77 -0.66 4.49e-17 Pediatric autoimmune diseases; TGCT cis rs2455799 0.634 rs62243670 chr3:15918990 C/T cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.68e-6 Mean platelet volume; TGCT cis rs4975616 0.839 rs2447853 chr5:1333077 A/G cg07493874 chr5:1342172 CLPTM1L -0.28 -6.52 -0.51 1.63e-9 Lung cancer; TGCT cis rs727563 0.593 rs5758461 chr22:42162189 G/C cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1862618 0.853 rs832554 chr5:56115036 A/G cg20203395 chr5:56204925 C5orf35 -0.57 -4.84 -0.4 3.8e-6 Initial pursuit acceleration; TGCT cis rs12579753 0.917 rs12311988 chr12:82177209 C/A cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs60871478 0.898 rs4725241 chr7:796883 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 0.44 4.51 0.38 1.46e-5 Cerebrospinal P-tau181p levels; TGCT cis rs13424612 1.000 rs4149551 chr2:240921463 C/T cg26363272 chr2:240904871 NDUFA10 0.29 4.9 0.4 2.99e-6 Odorant perception (isobutyraldehyde); TGCT cis rs7432375 0.566 rs835636 chr3:136674500 A/C cg15507776 chr3:136538369 TMEM22 0.54 5.68 0.45 9.18e-8 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs2836974 0.604 rs2854727 chr21:40713787 A/G cg11644478 chr21:40555479 PSMG1 0.62 5.83 0.46 4.48e-8 Cognitive function; TGCT cis rs9914544 0.564 rs8072860 chr17:18807884 T/C cg26378065 chr17:18585709 ZNF286B 0.51 4.5 0.37 1.53e-5 Educational attainment (years of education); TGCT cis rs1385374 0.858 rs11059923 chr12:129293057 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs4973397 0.810 rs12694890 chr2:232276553 A/T cg09339159 chr2:232260559 B3GNT7 -0.53 -4.55 -0.38 1.27e-5 Anti-saccade response; TGCT cis rs12458462 0.892 rs2242174 chr18:77458037 T/C cg11879182 chr18:77439856 CTDP1 0.71 8.16 0.59 3.11e-13 Monocyte count; TGCT cis rs7666738 0.716 rs7656233 chr4:99079237 G/A cg17366294 chr4:99064904 C4orf37 0.71 6.87 0.53 2.73e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg05025164 chr4:1340916 KIAA1530 0.68 5.65 0.45 1.05e-7 Longevity; TGCT cis rs7811142 0.943 rs11769886 chr7:99998607 G/A cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs61935443 0.673 rs11107770 chr12:95275147 C/T cg21533806 chr12:95267307 NA -0.5 -4.5 -0.37 1.52e-5 Schizophrenia; TGCT cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1005277 0.579 rs1985707 chr10:38434098 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.25 -0.6 1.91e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7296418 0.961 rs12425850 chr12:123501972 T/C cg00376283 chr12:123451042 ABCB9 0.86 8.06 0.59 5.57e-13 Platelet count; TGCT cis rs1371867 0.875 rs1371868 chr8:101330267 C/T cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs9302001 0.960 rs1408651 chr13:95460891 G/A cg07483244 chr13:95358924 NA 0.37 4.81 0.4 4.22e-6 Panic disorder; TGCT cis rs9926296 0.572 rs2079671 chr16:89884981 T/C cg21285383 chr16:89894308 SPIRE2 0.34 4.87 0.4 3.36e-6 Vitiligo; TGCT cis rs916888 0.697 rs199516 chr17:44856485 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.75 -5.26 -0.43 6.07e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1062177 0.950 rs59580263 chr5:151269577 T/A cg12924095 chr5:151150029 G3BP1 0.37 5.04 0.41 1.59e-6 Preschool internalizing problems; TGCT cis rs806215 1.000 rs712703 chr7:127257498 C/T cg25922125 chr7:127225783 GCC1 -0.58 -6.05 -0.48 1.56e-8 Type 2 diabetes; TGCT cis rs6570726 0.791 rs9373466 chr6:145912016 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.75 0.39 5.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 0.692 rs1867197 chr15:76910031 A/G cg26408565 chr15:76604113 ETFA 0.35 4.53 0.38 1.36e-5 Blood metabolite levels; TGCT cis rs80282103 0.571 rs56183119 chr10:1068370 C/T cg08668510 chr10:1095578 IDI1 1.1 5.19 0.42 8.32e-7 Glomerular filtration rate (creatinine); TGCT cis rs9303401 0.659 rs12602808 chr17:56698420 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs3806843 0.735 rs2563314 chr5:140047289 A/G cg19875535 chr5:140030758 IK -0.36 -6.15 -0.48 9.57e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9467773 1.000 rs10946834 chr6:26533664 G/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9811920 0.683 rs10936003 chr3:99667565 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.45 5.33 0.43 4.52e-7 Axial length; TGCT cis rs9393692 0.645 rs28446029 chr6:26305801 C/G cg00631329 chr6:26305371 NA -0.46 -6.91 -0.53 2.23e-10 Educational attainment; TGCT trans rs1814175 0.541 rs12287397 chr11:49819799 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT trans rs7819412 0.511 rs2409799 chr8:11435927 G/C cg06636001 chr8:8085503 FLJ10661 -0.76 -6.96 -0.53 1.71e-10 Triglycerides; TGCT cis rs4788570 0.538 rs72797713 chr16:71534208 G/A cg06353428 chr16:71660113 MARVELD3 -1.32 -7.86 -0.58 1.6e-12 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.716 rs8025134 chr15:76781729 C/T cg26408565 chr15:76604113 ETFA -0.39 -5.24 -0.43 6.74e-7 Blood metabolite levels; TGCT cis rs1799949 0.965 rs11080034 chr17:41443014 T/C cg10047753 chr17:41438598 NA 0.79 7.58 0.56 7.06e-12 Menopause (age at onset); TGCT cis rs1857353 1.000 rs114407954 chr1:75871366 C/A cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT trans rs9388451 0.839 rs980014 chr6:126068001 T/G cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.29 -0.6 1.61e-13 Brugada syndrome; TGCT cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2073300 1.000 rs6048824 chr20:23457645 C/A cg09953122 chr20:23471693 CST8 -0.59 -4.71 -0.39 6.5e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs6969780 0.632 rs11762730 chr7:27190398 A/C cg17457637 chr7:27170717 HOXA4 -0.36 -4.48 -0.37 1.71e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs539096 0.500 rs2906457 chr1:44338575 A/C cg13606994 chr1:44402422 ARTN -0.42 -4.52 -0.38 1.44e-5 Intelligence (multi-trait analysis); TGCT cis rs3015497 0.789 rs2356457 chr14:51116863 C/T cg04730355 chr14:51134070 SAV1 -0.65 -6.27 -0.49 5.6e-9 Mean platelet volume; TGCT cis rs2836950 0.545 rs4818001 chr21:40575088 T/C cg11644478 chr21:40555479 PSMG1 -0.49 -4.57 -0.38 1.17e-5 Menarche (age at onset); TGCT cis rs7010267 0.692 rs2073618 chr8:119964052 G/C cg17171407 chr8:119960777 TNFRSF11B 0.25 4.45 0.37 1.86e-5 Total body bone mineral density (age 45-60); TGCT cis rs1903068 0.925 rs1551645 chr4:55994314 T/G cg09978860 chr4:56023921 NA 0.58 6.38 0.5 3.16e-9 Endometriosis; TGCT cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg05738196 chr6:26577821 NA -0.5 -4.77 -0.39 5.05e-6 Schizophrenia; TGCT cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs9653442 0.835 rs7565967 chr2:100744683 G/T cg07810366 chr2:100720526 AFF3 -0.47 -7.82 -0.57 1.99e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9788682 1.000 rs2036534 chr15:78826948 T/C cg06917634 chr15:78832804 PSMA4 -0.71 -4.93 -0.4 2.63e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs1448094 0.556 rs4897831 chr12:86168248 C/T cg02569458 chr12:86230093 RASSF9 0.37 4.46 0.37 1.83e-5 Major depressive disorder; TGCT cis rs904251 0.523 rs2776874 chr6:37483197 C/T cg25019722 chr6:37503610 NA -0.48 -7.81 -0.57 2.09e-12 Cognitive performance; TGCT cis rs9394841 0.667 rs9357366 chr6:41786976 T/G cg08135965 chr6:41755394 TOMM6 0.55 5.15 0.42 9.77e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs71435601 0.628 rs530474 chr2:21381435 G/A cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.66e-5 Cholesterol, total; TGCT cis rs17221829 0.549 rs9666894 chr11:89358359 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs617219 0.671 rs2591388 chr5:78557241 A/G cg09550809 chr5:78407562 BHMT 0.39 5.17 0.42 9.09e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs12950390 0.893 rs4794110 chr17:45847230 A/G cg06532163 chr17:45867833 NA 0.31 5.33 0.43 4.49e-7 IgG glycosylation; TGCT cis rs1799949 1.000 rs11654731 chr17:41326940 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs7017914 0.905 rs3098870 chr8:71929935 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs6969780 0.915 rs4722657 chr7:27157756 G/A cg04321618 chr7:27170880 HOXA4 -0.5 -4.81 -0.4 4.35e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT trans rs2235808 0.554 rs6031453 chr20:42833144 C/T cg01217180 chr20:25176214 ENTPD6 0.96 6.63 0.51 9.44e-10 Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.754 rs12506610 chr4:120241659 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs10479542 1.000 rs10479542 chr5:178981241 T/A cg09060608 chr5:178986726 RUFY1 0.49 5.59 0.45 1.36e-7 Lung cancer; TGCT cis rs7258465 1.000 rs2278238 chr19:18576484 T/C cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg03517284 chr6:25882590 NA -0.5 -5.18 -0.42 8.55e-7 Height; TGCT cis rs724767 1.000 rs73065951 chr3:193721651 T/A cg19410732 chr3:194305082 NA -0.65 -4.68 -0.39 7.33e-6 Estradiol plasma levels (breast cancer); TGCT cis rs2862064 0.932 rs1553319 chr5:156479001 T/A cg12943317 chr5:156479607 HAVCR1 -0.46 -5.54 -0.45 1.74e-7 Platelet count; TGCT cis rs7432375 0.899 rs6439655 chr3:136466599 A/G cg12473912 chr3:136751656 NA -0.36 -5.11 -0.42 1.19e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs10193935 1.000 rs12618105 chr2:42414146 T/G cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6546537 0.826 rs2704443 chr2:69889338 A/C cg10773587 chr2:69614142 GFPT1 -0.82 -7.07 -0.54 1.01e-10 Serum thyroid-stimulating hormone levels; TGCT trans rs629535 0.814 rs62513373 chr8:70080753 C/T cg21567404 chr3:27674614 NA -0.57 -8.99 -0.63 3.38e-15 Dupuytren's disease; TGCT cis rs425277 0.583 rs4648807 chr1:2040898 A/G cg24578937 chr1:2090814 PRKCZ -0.23 -5.38 -0.44 3.57e-7 Height; TGCT cis rs3820928 0.904 rs10933161 chr2:227764872 A/G cg11843606 chr2:227700838 RHBDD1 -0.53 -4.68 -0.39 7.31e-6 Pulmonary function; TGCT cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs6938 0.596 rs11072511 chr15:75159433 A/G cg09165964 chr15:75287851 SCAMP5 0.55 5.18 0.42 8.56e-7 Breast cancer; TGCT cis rs6733011 0.519 rs6739097 chr2:99458601 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.85 -0.4 3.55e-6 Bipolar disorder; TGCT cis rs8077577 0.895 rs11078412 chr17:18100618 C/T cg09161412 chr17:18057145 MYO15A 0.63 5.06 0.41 1.46e-6 Obesity-related traits; TGCT cis rs1801251 0.964 rs10933411 chr2:233706847 A/G cg08000102 chr2:233561755 GIGYF2 -0.63 -6.46 -0.5 2.2e-9 Coronary artery disease; TGCT cis rs2033711 0.870 rs11084545 chr19:58951693 G/C cg04608855 chr19:58913158 NA 0.58 5.64 0.45 1.11e-7 Uric acid clearance; TGCT cis rs1355223 0.583 rs2956076 chr11:34874124 T/C cg11058730 chr11:34937778 PDHX;APIP 0.79 8.54 0.61 4.08e-14 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs7223966 1.000 rs11657120 chr17:61857218 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7582180 0.544 rs13026570 chr2:100939498 A/C cg14675211 chr2:100938903 LONRF2 0.49 4.75 0.39 5.48e-6 Intelligence (multi-trait analysis); TGCT cis rs1691799 0.899 rs1168314 chr12:66746937 A/G cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.87e-9 White blood cell count (basophil); TGCT cis rs950169 0.840 rs62029595 chr15:84955301 C/T cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs2456568 0.802 rs10765639 chr11:93636194 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -6.44 -0.5 2.38e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6951245 1.000 rs77702926 chr7:1088838 G/A cg23708337 chr7:1209742 NA 0.56 5.08 0.42 1.34e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7617773 0.963 rs12495221 chr3:48179178 C/T cg11946769 chr3:48343235 NME6 -0.58 -5.14 -0.42 1.03e-6 Coronary artery disease; TGCT cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg20887711 chr4:1340912 KIAA1530 -0.88 -8.34 -0.6 1.21e-13 Longevity; TGCT cis rs4925386 1.000 rs4925382 chr20:60918542 G/C cg06026331 chr20:60912101 LAMA5 -0.3 -5.5 -0.44 2.12e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs1891275 0.515 rs7098763 chr10:93444827 C/T cg07889827 chr10:93443413 NA -0.33 -6.99 -0.53 1.53e-10 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg06873352 chr17:61820015 STRADA 0.53 5.82 0.46 4.67e-8 Prudent dietary pattern; TGCT cis rs1008375 0.897 rs1006723 chr4:17618524 G/A cg16339924 chr4:17578868 LAP3 0.68 5.49 0.44 2.14e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 0.844 rs6107017 chr20:25232300 A/G cg14121845 chr20:25566513 NINL 0.49 4.96 0.41 2.24e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg01585852 chr22:24235823 MIF -0.21 -4.56 -0.38 1.23e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7726839 0.540 rs61731455 chr5:665295 A/G cg16624210 chr5:671434 TPPP 0.42 4.89 0.4 3.06e-6 Obesity-related traits; TGCT cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs28386778 0.897 rs8077013 chr17:61850392 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs9926296 0.607 rs2079672 chr16:89884917 A/G cg03388025 chr16:89894329 SPIRE2 -0.34 -5.01 -0.41 1.81e-6 Vitiligo; TGCT cis rs13177918 0.603 rs2748241 chr5:149827494 C/T cg14059543 chr5:149831962 NA -0.7 -10.23 -0.68 3.52e-18 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2932538 0.922 rs12750621 chr1:113206502 G/C cg10983938 chr1:113465962 AFARP1;SLC16A1 0.21 4.51 0.38 1.51e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs79387448 1.000 rs79387448 chr2:103215410 C/T cg09003973 chr2:102972529 NA 0.91 5.44 0.44 2.71e-7 Gut microbiota (bacterial taxa); TGCT cis rs10504229 0.728 rs72650860 chr8:58153111 A/G cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg11494091 chr17:61959527 GH2 0.62 15.19 0.81 4.3e-30 Prudent dietary pattern; TGCT cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg05754148 chr16:3507555 NAT15 0.41 4.93 0.4 2.63e-6 Tuberculosis; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg24846343 chr22:24311635 DDTL 0.23 5.7 0.46 8.19e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg06634786 chr22:41940651 POLR3H -0.86 -8.34 -0.6 1.18e-13 Vitiligo; TGCT trans rs1814175 0.616 rs1722020 chr11:49904189 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.24e-19 Height; TGCT cis rs8032315 0.895 rs4932370 chr15:91404705 A/G cg03209642 chr15:91427605 FES -0.52 -4.96 -0.41 2.24e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs11722228 0.521 rs56403947 chr4:10112529 T/G cg26043149 chr18:55253948 FECH 1.17 12.23 0.74 4.71e-23 Gout;Urate levels;Serum uric acid levels; TGCT cis rs11122272 0.735 rs2572248 chr1:231514942 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs854765 0.964 rs854764 chr17:18011750 A/G cg00306284 chr17:18855313 SLC5A10 -0.24 -4.51 -0.38 1.5e-5 Total body bone mineral density; TGCT cis rs1971762 0.730 rs12830769 chr12:54087705 G/A cg09709951 chr12:54017699 ATF7 0.36 5.2 0.42 7.91e-7 Height; TGCT cis rs950169 1.000 rs950169 chr15:84706461 C/T cg17173187 chr15:85201210 NMB 0.49 5.45 0.44 2.64e-7 Schizophrenia; TGCT cis rs8081395 0.775 rs2526355 chr17:57953233 G/C cg16369400 chr17:58041258 RNFT1 0.23 4.47 0.37 1.72e-5 White blood cell count; TGCT cis rs80282103 0.618 rs74120451 chr10:1126866 T/C cg08668510 chr10:1095578 IDI1 1.09 5.31 0.43 4.98e-7 Glomerular filtration rate (creatinine); TGCT cis rs17122693 1.000 rs1018036 chr14:51085429 C/T cg04730355 chr14:51134070 SAV1 1.21 9.01 0.63 3.15e-15 Cognitive performance; TGCT cis rs2153535 0.580 rs9379210 chr6:8461928 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9303401 0.527 rs12946522 chr17:56768103 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.62 5.52 0.44 1.93e-7 Cognitive test performance; TGCT cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg23103009 chr10:134564232 INPP5A 0.28 4.44 0.37 1.94e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9611565 0.694 rs79011 chr22:41866938 A/G cg17554472 chr22:41940697 POLR3H 0.5 5.16 0.42 9.35e-7 Vitiligo; TGCT cis rs6952808 0.573 rs12668848 chr7:2020995 G/A cg04267008 chr7:1944627 MAD1L1 -0.34 -4.44 -0.37 1.99e-5 Bipolar disorder and schizophrenia; TGCT cis rs7659604 0.539 rs7660548 chr4:122730821 G/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.31 -0.43 4.82e-7 Type 2 diabetes; TGCT cis rs10791097 0.694 rs2155749 chr11:130751094 G/T cg14779329 chr11:130786720 SNX19 0.29 5.01 0.41 1.85e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6951245 1.000 rs1997243 chr7:1083777 A/G cg18402987 chr7:1209562 NA 0.7 5.71 0.46 7.73e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs77633900 0.614 rs2459363 chr15:76874952 T/C cg21673338 chr15:77095150 SCAPER -0.52 -4.83 -0.4 3.88e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs57590327 0.679 rs13094809 chr3:81666806 G/A cg07356753 chr3:81810745 GBE1 -0.62 -5.01 -0.41 1.85e-6 Extraversion; TGCT cis rs2677744 0.626 rs11854429 chr15:91489685 C/T cg23684204 chr15:91497937 RCCD1 -0.36 -5.44 -0.44 2.69e-7 Attention deficit hyperactivity disorder; TGCT cis rs7666738 0.830 rs9996098 chr4:98867740 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10489525 0.502 rs12026930 chr1:115597836 G/A cg12756093 chr1:115239321 AMPD1 -0.41 -5.8 -0.46 5.26e-8 Autism; TGCT cis rs2120019 0.938 rs3850093 chr15:75318482 A/G cg09165964 chr15:75287851 SCAMP5 1.21 10.33 0.68 2.05e-18 Blood trace element (Zn levels); TGCT cis rs7666738 0.791 rs2081622 chr4:98927369 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2280018 0.526 rs2966128 chr16:15153389 G/T cg07549590 chr16:15018862 NA -0.35 -5.24 -0.43 6.59e-7 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid);Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs1008375 0.898 rs61047804 chr4:17593965 G/A cg16339924 chr4:17578868 LAP3 0.81 6.69 0.52 6.75e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4986172 0.539 rs12603813 chr17:43196584 T/C cg10701640 chr17:43249399 NA 0.45 5.42 0.44 3.03e-7 Height; TGCT cis rs11864453 0.611 rs1050361 chr16:72130203 C/G cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs6906287 0.647 rs11153753 chr6:118836153 T/C cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs909674 0.690 rs1972280 chr22:39831986 T/A cg24399712 chr22:39784796 NA -1.06 -10.99 -0.7 4.84e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4285214 0.715 rs10079692 chr5:124025450 A/G cg15082166 chr5:124005151 ZNF608 -0.36 -4.89 -0.4 3.08e-6 Survival in pancreatic cancer; TGCT cis rs3741404 0.620 rs11231722 chr11:63967770 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 8.19 0.59 2.77e-13 Platelet count; TGCT cis rs4727027 0.737 rs10278971 chr7:148780659 A/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.77 0.39 5.09e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6450176 0.538 rs12186486 chr5:53306549 T/A ch.5.1024479R chr5:53302184 ARL15 -0.87 -6.8 -0.52 3.92e-10 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs9399135 0.967 rs7763836 chr6:135362378 T/C cg24558204 chr6:135376177 HBS1L 0.46 4.56 0.38 1.22e-5 Red blood cell count; TGCT cis rs12367572 0.965 rs1506676 chr12:45237401 T/C cg04608330 chr12:45269318 NELL2 -0.5 -4.65 -0.39 8.44e-6 Gut microbiome composition (summer); TGCT cis rs11190604 1.000 rs10883496 chr10:102221931 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs651907 0.557 rs11711079 chr3:101386918 G/A cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs3008870 0.709 rs62883160 chr1:67392889 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.79 8.43 0.6 7.38e-14 Lymphocyte percentage of white cells; TGCT cis rs4888262 0.526 rs4888253 chr16:74583146 C/T cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 7.94e-11 Testicular germ cell tumor; TGCT cis rs780096 0.546 rs4425043 chr2:27733452 G/A cg12000995 chr2:27665139 KRTCAP3 -0.39 -4.72 -0.39 6.14e-6 Total body bone mineral density; TGCT cis rs796364 1.000 rs281760 chr2:200787804 A/G cg17644776 chr2:200775616 C2orf69 0.31 4.85 0.4 3.58e-6 Schizophrenia; TGCT cis rs8060598 0.528 rs4785452 chr16:50842077 T/C cg04429994 chr16:51093890 NA 0.18 4.89 0.4 3.05e-6 Leprosy; TGCT cis rs4727027 0.866 rs1358062 chr7:148783743 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.54 5.04 0.41 1.57e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7843479 0.601 rs727693 chr8:21850116 A/G cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.11e-12 Mean corpuscular volume; TGCT cis rs12049351 0.722 rs6703347 chr1:229626166 A/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs1218582 0.741 rs2335407 chr1:154843347 A/G cg09359103 chr1:154839909 KCNN3 0.74 15.9 0.82 1.02e-31 Prostate cancer; TGCT cis rs13256369 1.000 rs1109619 chr8:8571616 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs13108904 0.935 rs1732100 chr4:1281761 C/T cg00684032 chr4:1343700 KIAA1530 -0.22 -4.73 -0.39 6.06e-6 Obesity-related traits; TGCT cis rs1153858 1.000 rs11858495 chr15:45637662 A/G cg26924012 chr15:45694286 SPATA5L1 -1.06 -12.44 -0.75 1.44e-23 Homoarginine levels; TGCT cis rs7647973 0.626 rs7649428 chr3:49868876 A/T cg03060546 chr3:49711283 APEH -0.63 -5.57 -0.45 1.52e-7 Menarche (age at onset); TGCT cis rs12421382 0.511 rs2212430 chr11:109289538 C/T cg16359550 chr11:109292809 C11orf87 0.69 7.54 0.56 8.55e-12 Schizophrenia; TGCT cis rs1552244 1.000 rs6764068 chr3:10153842 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.5 -6.94 -0.53 1.89e-10 Alzheimer's disease; TGCT cis rs933688 1.000 rs985434 chr5:90744509 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.47 0.61 6.09e-14 Smoking behavior; TGCT cis rs1005277 0.579 rs2504140 chr10:38387579 T/G cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs7267979 1.000 rs2259837 chr20:25280205 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2836974 0.666 rs4624474 chr21:40686327 T/C cg11644478 chr21:40555479 PSMG1 -0.58 -5.1 -0.42 1.23e-6 Cognitive function; TGCT cis rs7975161 0.520 rs9739833 chr12:104737430 A/T cg25273343 chr12:104657179 TXNRD1 -0.35 -4.72 -0.39 6.28e-6 Toenail selenium levels; TGCT cis rs7772486 0.875 rs13198450 chr6:146370524 C/A cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs11098499 0.657 rs9996569 chr4:120299004 G/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs7246657 0.722 rs3829688 chr19:38077100 T/C cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs546131 0.890 rs485845 chr11:34830389 G/T cg06937548 chr11:34938143 PDHX;APIP -0.67 -5.94 -0.47 2.65e-8 Lung disease severity in cystic fibrosis; TGCT cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg04267008 chr7:1944627 MAD1L1 -0.4 -5.28 -0.43 5.67e-7 Bipolar disorder and schizophrenia; TGCT cis rs1008375 1.000 rs2872958 chr4:17665032 A/G cg18681998 chr4:17616180 MED28 0.94 11.11 0.71 2.49e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs981844 1.000 rs72731672 chr4:154664925 G/T cg14289246 chr4:154710475 SFRP2 1.0 8.25 0.6 1.96e-13 Response to statins (LDL cholesterol change); TGCT cis rs6089829 0.855 rs4809459 chr20:61661345 C/T cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs9916302 0.904 rs55660616 chr17:37684990 C/A cg07936489 chr17:37558343 FBXL20 -0.61 -4.92 -0.4 2.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs62064224 0.589 rs9889607 chr17:30785585 A/C cg18200150 chr17:30822561 MYO1D -0.38 -4.66 -0.39 8.03e-6 Schizophrenia; TGCT cis rs473651 0.935 rs515412 chr2:239345394 A/T cg18131467 chr2:239335373 ASB1 0.97 13.84 0.78 6.56e-27 Multiple system atrophy; TGCT cis rs7714584 1.000 rs11748553 chr5:150184553 A/G cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs1865760 0.566 rs9295686 chr6:26081983 G/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.13e-6 Height; TGCT cis rs514406 0.505 rs387436 chr1:53179376 C/T cg24675658 chr1:53192096 ZYG11B 0.79 9.71 0.66 6.32e-17 Monocyte count; TGCT cis rs1799949 0.501 rs9675035 chr17:41415016 A/T cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs7086627 0.515 rs7077373 chr10:82211615 C/T cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs801193 1.000 rs4279493 chr7:66226620 C/T cg00343986 chr7:65444356 GUSB 0.23 5.13 0.42 1.08e-6 Aortic root size; TGCT cis rs13202913 0.748 rs2859824 chr6:151815865 C/A cg03627880 chr6:151815985 C6orf97 -0.62 -5.75 -0.46 6.43e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7523050 0.643 rs35907086 chr1:109406625 A/G cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs4494114 1.000 rs4589074 chr1:39354508 T/G cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.1e-9 Blood protein levels; TGCT cis rs7666738 0.830 rs11935588 chr4:98979862 A/G cg17366294 chr4:99064904 C4orf37 -0.71 -7.11 -0.54 7.99e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.679 rs12375285 chr8:58040084 G/A cg21724239 chr8:58056113 NA 0.34 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs1153858 1.000 rs1153849 chr15:45695695 G/A cg14582100 chr15:45693742 SPATA5L1 0.47 5.62 0.45 1.22e-7 Homoarginine levels; TGCT cis rs4642101 0.512 rs9813960 chr3:12818205 A/G cg05775895 chr3:12838266 CAND2 0.76 7.82 0.57 2e-12 QRS complex (12-leadsum); TGCT cis rs72781680 0.821 rs12623521 chr2:24181670 C/T cg08917208 chr2:24149416 ATAD2B 0.72 4.5 0.37 1.56e-5 Lymphocyte counts; TGCT cis rs2456568 0.805 rs55784864 chr11:93682887 G/A cg16099599 chr11:93583650 C11orf90 -0.39 -4.69 -0.39 7.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9788682 0.948 rs59133824 chr15:78833450 C/A cg24631222 chr15:78858424 CHRNA5 0.92 7.57 0.56 7.51e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg02353165 chr6:42928485 GNMT 0.99 9.9 0.66 2.25e-17 Alzheimer's disease in APOE e4+ carriers; TGCT trans rs2288327 0.557 rs7577862 chr2:179352857 G/A cg18634211 chr1:26737262 LIN28 0.91 6.86 0.52 2.86e-10 Atrial fibrillation; TGCT cis rs4879913 0.801 rs7047802 chr9:35591601 G/A cg18130437 chr9:35658183 CCDC107;RMRP -0.5 -4.95 -0.41 2.38e-6 Electroencephalogram traits; TGCT cis rs7412746 0.611 rs36008098 chr1:150856806 G/A cg09365446 chr1:150670422 GOLPH3L 0.35 5.0 0.41 1.87e-6 Melanoma; TGCT cis rs3008870 1.000 rs12044278 chr1:67460977 T/C cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs447921 0.813 rs4419085 chr17:74443683 C/T cg09812376 chr17:74270190 QRICH2 0.47 4.97 0.41 2.17e-6 Mitochondrial DNA levels; TGCT cis rs501916 1.000 rs648627 chr15:48055738 C/T cg16110827 chr15:48056943 SEMA6D -0.17 -5.12 -0.42 1.12e-6 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs4803468 1.000 rs284663 chr19:41932612 C/T cg09537434 chr19:41945824 ATP5SL -0.91 -10.05 -0.67 9.48e-18 Height; TGCT cis rs231513 0.954 rs231506 chr17:41970191 A/G cg26893861 chr17:41843967 DUSP3 -0.71 -5.14 -0.42 1.05e-6 Cognitive function; TGCT cis rs17253792 0.749 rs74979160 chr14:56097568 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7267979 1.000 rs6050626 chr20:25428261 T/C cg03522245 chr20:25566470 NINL 0.63 6.84 0.52 3.25e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6912958 0.559 rs242287 chr6:88071825 C/T cg10393598 chr6:87862264 NA -0.32 -4.48 -0.37 1.67e-5 Monocyte percentage of white cells; TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.12e-6 Prudent dietary pattern; TGCT cis rs7772486 0.651 rs1292338 chr6:145967471 A/C cg23711669 chr6:146136114 FBXO30 -0.83 -8.98 -0.63 3.75e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs4851266 1.000 rs11687241 chr2:100824595 A/G cg07810366 chr2:100720526 AFF3 -0.41 -5.82 -0.46 4.72e-8 Educational attainment; TGCT cis rs7647973 0.807 rs4955416 chr3:49108428 T/C cg07636037 chr3:49044803 WDR6 0.79 6.56 0.51 1.32e-9 Menarche (age at onset); TGCT cis rs9788682 0.747 rs8042059 chr15:78907859 A/C cg24631222 chr15:78858424 CHRNA5 0.77 5.91 0.47 3.06e-8 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs4819052 0.851 rs8133045 chr21:46658137 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13191362 0.872 rs13196631 chr6:163001588 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3820928 0.874 rs13383070 chr2:227904939 C/T cg11843606 chr2:227700838 RHBDD1 -0.53 -5.03 -0.41 1.7e-6 Pulmonary function; TGCT cis rs1865760 0.622 rs10946807 chr6:26079638 T/C cg16482183 chr6:26056742 HIST1H1C 0.68 5.62 0.45 1.17e-7 Height; TGCT cis rs13217239 0.646 rs9379956 chr6:27033735 T/C cg05738196 chr6:26577821 NA -0.51 -4.92 -0.4 2.71e-6 Schizophrenia; TGCT cis rs739496 0.579 rs4767068 chr12:112281013 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs362272 0.524 rs881816 chr4:3365366 A/G cg22655196 chr4:3374909 RGS12 0.22 4.45 0.37 1.86e-5 Serum sulfate level; TGCT cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg18402987 chr7:1209562 NA 0.37 4.55 0.38 1.25e-5 Longevity;Endometriosis; TGCT cis rs4862750 0.914 rs1346126 chr4:187876404 T/C cg11301795 chr4:187892539 NA -0.34 -5.25 -0.43 6.45e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs9381040 0.610 rs6941090 chr6:41043465 G/A cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs1005277 0.541 rs2472177 chr10:38384015 T/G cg25427524 chr10:38739819 LOC399744 -0.38 -7.91 -0.58 1.23e-12 Extrinsic epigenetic age acceleration; TGCT cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs910316 0.934 rs7141705 chr14:75655352 G/C cg23033748 chr14:75592666 NEK9 -0.27 -4.51 -0.38 1.5e-5 Height; TGCT cis rs7659604 0.628 rs3828485 chr4:122722368 G/A cg06713675 chr4:122721982 EXOSC9 -0.7 -9.58 -0.65 1.32e-16 Type 2 diabetes; TGCT cis rs7542091 0.813 rs2049999 chr1:210031331 A/G cg05527609 chr1:210001259 C1orf107 -0.51 -4.51 -0.38 1.48e-5 Monobrow; TGCT cis rs59197085 0.534 rs2307039 chr7:128449355 A/G cg00260937 chr7:128520193 KCP 0.47 4.9 0.4 2.92e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs6688613 1.000 rs7528849 chr1:166954870 A/G cg07049167 chr1:166818506 POGK 0.22 4.72 0.39 6.29e-6 Refractive astigmatism; TGCT cis rs4319547 0.915 rs7966094 chr12:123115771 A/G cg05707623 chr12:122985044 ZCCHC8 -0.68 -5.42 -0.44 3.02e-7 Body mass index; TGCT cis rs208520 0.690 rs12213575 chr6:66735989 A/G cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs9902453 0.765 rs1531553 chr17:28066752 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.4 -0.6 8.88e-14 Coffee consumption (cups per day); TGCT cis rs10883723 0.773 rs715439 chr10:104257809 A/C cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12541335 0.603 rs9792127 chr8:22180334 G/A cg02463440 chr8:22132932 PIWIL2 0.26 5.16 0.42 9.37e-7 Hypertriglyceridemia; TGCT cis rs7772486 0.875 rs6570736 chr6:146388320 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1784581 0.802 rs6455787 chr6:162411378 G/A cg17173639 chr6:162384350 PARK2 0.42 7.3 0.55 3.02e-11 Itch intensity from mosquito bite; TGCT cis rs1862618 0.620 rs189695 chr5:56225769 T/C cg24531977 chr5:56204891 C5orf35 -0.68 -7.22 -0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs9926296 0.632 rs4785717 chr16:89801133 A/G cg27121462 chr16:89883253 FANCA 0.55 5.06 0.41 1.45e-6 Vitiligo; TGCT cis rs9611565 0.559 rs5758412 chr22:42080803 T/A cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Vitiligo; TGCT cis rs595982 0.527 rs55670257 chr19:49382654 G/A cg15549821 chr19:49342101 PLEKHA4 -0.69 -8.7 -0.62 1.73e-14 Red cell distribution width; TGCT cis rs61884328 0.535 rs4647735 chr11:47253075 T/A cg13308137 chr11:47528955 CUGBP1 0.39 5.41 0.44 3.13e-7 Total body bone mineral density (age over 60); TGCT cis rs5750830 0.597 rs4821889 chr22:39777254 T/C cg05872129 chr22:39784769 NA -0.9 -10.38 -0.68 1.51e-18 Intelligence (multi-trait analysis); TGCT cis rs9393692 1.000 rs2393593 chr6:26285683 T/C cg05868516 chr6:26286170 HIST1H4H 0.62 5.75 0.46 6.64e-8 Educational attainment; TGCT cis rs3749237 0.964 rs1799845 chr3:49847623 A/G cg03060546 chr3:49711283 APEH 0.71 7.31 0.55 2.8e-11 Resting heart rate; TGCT cis rs16957091 0.647 rs3759792 chr15:43252764 A/G cg17935677 chr15:44119062 WDR76 0.53 4.7 0.39 6.83e-6 MGMT methylation in smokers; TGCT cis rs710216 0.917 rs900837 chr1:43412793 A/G cg03128534 chr1:43423976 SLC2A1 -0.56 -4.53 -0.38 1.35e-5 Red cell distribution width; TGCT cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs3776081 0.600 rs2302273 chr5:149535255 G/A cg18424208 chr5:149546337 CDX1 -0.25 -4.48 -0.37 1.66e-5 Blood protein levels; TGCT cis rs1348850 0.914 rs4893961 chr2:178411075 A/G cg22681709 chr2:178499509 PDE11A -0.36 -4.77 -0.39 5.03e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1570884 0.516 rs9316463 chr13:50176844 G/A cg03651054 chr13:50194643 NA 0.33 5.28 0.43 5.66e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs7246657 0.524 rs10411251 chr19:37428755 C/T cg18154014 chr19:37997991 ZNF793 0.69 4.51 0.38 1.46e-5 Coronary artery calcification; TGCT trans rs12339966 0.581 rs62529407 chr9:11331229 C/A cg03488587 chr11:64876988 C11orf2 0.32 7.03 0.53 1.19e-10 Systolic blood pressure; TGCT cis rs17376456 0.877 rs28539612 chr5:93499099 C/T cg25358565 chr5:93447407 FAM172A 0.97 8.32 0.6 1.34e-13 Diabetic retinopathy; TGCT cis rs1008375 1.000 rs2159584 chr4:17620568 G/A cg10189774 chr4:17578691 LAP3 0.6 5.21 0.42 7.64e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs986417 0.688 rs8018111 chr14:60964347 A/G cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs6665290 0.935 rs1929863 chr1:227195728 C/T cg10327440 chr1:227177885 CDC42BPA -1.0 -20.65 -0.88 6.07e-42 Myeloid white cell count; TGCT cis rs4595586 0.545 rs1156705 chr12:39372672 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs3020333 0.653 rs851983 chr6:152024415 A/G cg22157087 chr6:152012887 ESR1 0.23 5.65 0.45 1.04e-7 Total body bone mineral density; TGCT cis rs9902453 1.000 rs4074170 chr17:28381141 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs4372836 0.729 rs4666122 chr2:29092850 G/T cg09522027 chr2:28974177 PPP1CB 0.67 6.91 0.53 2.24e-10 Body mass index; TGCT cis rs6951245 1.000 rs6951245 chr7:1058193 G/A cg03188948 chr7:1209495 NA 0.55 4.56 0.38 1.2e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg15242686 chr22:24348715 GSTTP1 0.49 7.11 0.54 8.12e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467603 0.592 rs1184498 chr6:25864882 G/C cg16898833 chr6:26189333 HIST1H4D 0.75 4.61 0.38 9.91e-6 Intelligence (multi-trait analysis); TGCT cis rs881375 0.967 rs1548783 chr9:123658639 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.52 5.59 0.45 1.38e-7 Rheumatoid arthritis; TGCT cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg25767906 chr1:53392781 SCP2 0.5 5.83 0.46 4.53e-8 Monocyte count; TGCT cis rs3820068 0.705 rs4646087 chr1:15822404 A/G cg05660106 chr1:15850417 CASP9 1.18 13.63 0.77 2.04e-26 Systolic blood pressure; TGCT cis rs11148252 1.000 rs4886018 chr13:52990717 C/T cg00495681 chr13:53174319 NA 0.46 4.51 0.38 1.49e-5 Lewy body disease; TGCT cis rs644799 1.000 rs500054 chr11:95593806 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 10.89 0.7 8.66e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs28595532 0.764 rs115011450 chr4:119778171 C/T cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs61867294 0.501 rs7907824 chr10:106711060 G/A cg08000847 chr10:105880925 C10orf78 0.48 4.46 0.37 1.81e-5 Schizophrenia; TGCT cis rs9309473 0.607 rs6740173 chr2:73602266 C/G cg20560298 chr2:73613845 ALMS1 -0.41 -4.54 -0.38 1.31e-5 Metabolite levels; TGCT cis rs903263 0.965 rs6576960 chr1:84593913 T/G cg09664975 chr1:84543551 PRKACB 0.5 4.67 0.39 7.62e-6 Breast cancer (male); TGCT cis rs1371867 0.726 rs1660333 chr8:101309989 A/G cg06002616 chr8:101225028 SPAG1 -0.55 -6.38 -0.5 3.14e-9 Atrioventricular conduction; TGCT cis rs7698623 0.850 rs4693892 chr4:88796983 T/G cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs7772486 0.754 rs6932863 chr6:146021255 A/T cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs941408 1.000 rs1076448 chr19:2792343 G/A cg06609049 chr19:2785107 THOP1 0.8 7.95 0.58 9.77e-13 Total cholesterol levels; TGCT cis rs9788682 1.000 rs12441426 chr15:78812329 T/C cg06917634 chr15:78832804 PSMA4 -0.71 -5.21 -0.42 7.71e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9916302 0.904 rs9905432 chr17:37555918 C/A cg15445000 chr17:37608096 MED1 -0.34 -4.8 -0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg17554472 chr22:41940697 POLR3H -0.52 -5.37 -0.43 3.79e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2243480 1.000 rs1723269 chr7:65472786 C/G cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs1949733 0.598 rs4696838 chr4:8540349 A/G cg13073564 chr4:8508604 NA 0.49 4.8 0.4 4.48e-6 Response to antineoplastic agents; TGCT cis rs9430161 0.611 rs12081197 chr1:11034239 T/C cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs6831352 0.589 rs2602836 chr4:100014805 C/T cg12011299 chr4:100065546 ADH4 -0.37 -4.73 -0.39 5.98e-6 Alcohol dependence; TGCT cis rs7267979 0.789 rs4815400 chr20:25292560 T/C cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs938554 0.657 rs7679724 chr4:9985376 G/T cg00071950 chr4:10020882 SLC2A9 0.49 4.56 0.38 1.2e-5 Blood metabolite levels; TGCT cis rs422249 0.720 rs174455 chr11:61656117 A/G cg01500311 chr11:61656094 FADS3 -0.43 -9.35 -0.64 4.84e-16 Trans fatty acid levels; TGCT cis rs739401 0.566 rs7931504 chr11:3026712 C/T cg25174290 chr11:3078921 CARS 0.5 4.79 0.4 4.6e-6 Longevity; TGCT cis rs17331151 0.541 rs1139106 chr3:52871101 G/A cg07884673 chr3:53033167 SFMBT1 0.49 5.61 0.45 1.26e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7659604 0.582 rs3217780 chr4:122737278 T/C cg19748678 chr4:122722346 EXOSC9 0.9 9.35 0.64 4.81e-16 Type 2 diabetes; TGCT cis rs67460515 0.892 rs2054710 chr3:161090616 C/T cg03342759 chr3:160939853 NMD3 -0.52 -5.38 -0.44 3.56e-7 Parkinson's disease; TGCT cis rs10779751 1.000 rs11121698 chr1:11267283 C/T cg08854313 chr1:11322531 MTOR 0.92 10.28 0.68 2.6e-18 Body mass index; TGCT cis rs7010267 0.870 rs7014574 chr8:119977077 C/T cg17171407 chr8:119960777 TNFRSF11B 0.32 6.21 0.49 7.44e-9 Total body bone mineral density (age 45-60); TGCT cis rs4372836 0.504 rs12185717 chr2:29069551 C/A cg09522027 chr2:28974177 PPP1CB -0.57 -5.55 -0.45 1.63e-7 Body mass index; TGCT cis rs7923609 1.000 rs7910927 chr10:65138910 T/G cg08743896 chr10:65200160 JMJD1C -0.34 -4.57 -0.38 1.15e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs12286929 0.600 rs4445669 chr11:115045237 C/T cg04017736 chr11:115827165 NA 0.2 4.83 0.4 4.02e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7267979 1.000 rs3761117 chr20:25388070 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7786877 0.508 rs11765509 chr7:100310990 T/G cg16850897 chr7:100343110 ZAN -0.47 -4.45 -0.37 1.9e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1577917 0.958 rs12192033 chr6:86472559 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.22 -0.42 7.42e-7 Response to antipsychotic treatment; TGCT trans rs7618501 0.602 rs2301166 chr3:50148305 C/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.51 -0.65 1.92e-16 Intelligence (multi-trait analysis); TGCT cis rs155076 1.000 rs12870992 chr13:21846019 A/G cg11317459 chr13:21872234 NA 1.28 10.32 0.68 2.1e-18 White matter hyperintensity burden; TGCT cis rs4850410 0.581 rs12990099 chr2:197908096 T/G cg19149314 chr2:197065128 HECW2 0.23 4.51 0.38 1.46e-5 Interferon alpha levels in systemic lupus erythematosus; TGCT cis rs1903068 0.853 rs9312656 chr4:56002972 C/G cg01777861 chr4:56023843 NA 0.53 6.21 0.49 7.2e-9 Endometriosis; TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs739496 0.615 rs666951 chr12:112136583 C/A cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT trans rs901683 0.702 rs73292848 chr10:46169752 T/C cg03466342 chr12:52753899 KRT85 -0.6 -7.24 -0.55 4.23e-11 Red blood cell traits;Mean corpuscular volume; TGCT cis rs3820928 0.967 rs2396435 chr2:227778397 G/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs11771526 0.901 rs2191000 chr7:32275098 C/A cg27532318 chr7:32358331 NA 0.56 4.61 0.38 9.78e-6 Body mass index; TGCT cis rs8017423 0.967 rs55667096 chr14:90714798 C/T cg04374321 chr14:90722782 PSMC1 0.74 7.74 0.57 2.98e-12 Mortality in heart failure; TGCT cis rs1018836 0.859 rs10808614 chr8:91569677 C/G cg16814680 chr8:91681699 NA -0.75 -7.85 -0.58 1.71e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs736408 0.562 rs1014969 chr3:52808341 G/A cg10802521 chr3:52805072 NEK4 -0.82 -9.71 -0.66 6.55e-17 Bipolar disorder; TGCT cis rs12681288 0.823 rs6994989 chr8:1007284 C/A cg04851639 chr8:1020857 NA -0.36 -6.29 -0.49 4.97e-9 Schizophrenia; TGCT cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg03396347 chr1:1875803 NA -0.36 -6.58 -0.51 1.19e-9 Body mass index; TGCT cis rs4595586 0.545 rs12828866 chr12:39391925 C/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7237497 0.532 rs515151 chr18:12860934 G/C cg23598886 chr18:12777645 NA 0.56 4.91 0.4 2.77e-6 Inflammatory skin disease; TGCT cis rs6088590 0.965 rs6058108 chr20:33288655 A/G cg24642439 chr20:33292090 TP53INP2 0.68 6.14 0.48 1.02e-8 Coronary artery disease; TGCT cis rs910316 0.575 rs12889133 chr14:75465089 C/T cg08847533 chr14:75593920 NEK9 0.71 6.77 0.52 4.59e-10 Height; TGCT cis rs12210905 1.000 rs12153912 chr6:27179829 A/G cg08851530 chr6:28072375 NA -0.87 -4.87 -0.4 3.34e-6 Hip circumference adjusted for BMI; TGCT trans rs4650994 1.000 rs12138541 chr1:178518707 G/A cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.54e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9788682 0.633 rs2656070 chr15:78730252 A/G cg24631222 chr15:78858424 CHRNA5 -0.65 -4.87 -0.4 3.38e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs6121246 0.567 rs6058197 chr20:30194899 A/G cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs1635 0.655 rs73742536 chr6:28303243 G/A cg15743358 chr6:28303923 ZNF323 -1.28 -6.27 -0.49 5.57e-9 Schizophrenia; TGCT cis rs11585357 0.709 rs735281 chr1:17616194 T/C cg08277548 chr1:17600880 PADI3 0.96 9.72 0.66 5.97e-17 Hair shape; TGCT cis rs10782582 0.593 rs4638068 chr1:76161663 G/A cg22875332 chr1:76189707 ACADM -0.55 -6.35 -0.5 3.77e-9 Daytime sleep phenotypes; TGCT cis rs8013055 0.796 rs35592422 chr14:105996593 G/C cg19700328 chr14:106028568 NA -0.51 -5.67 -0.45 9.58e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9611565 0.500 rs10775759 chr22:42088158 T/C cg13695892 chr22:41940480 POLR3H 0.9 9.02 0.63 2.89e-15 Vitiligo; TGCT cis rs9911578 1.000 rs9904879 chr17:56864422 G/A cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7474896 0.583 rs11011347 chr10:38019264 G/A cg13720705 chr10:37990370 NA 0.34 4.9 0.4 2.9e-6 Obesity (extreme); TGCT cis rs76954792 0.826 rs62062240 chr17:30026212 C/T cg18427091 chr17:30115417 NA -0.35 -4.55 -0.38 1.24e-5 Coronary artery disease; TGCT cis rs13108904 0.901 rs1316393 chr4:1315619 A/G cg00684032 chr4:1343700 KIAA1530 -0.23 -4.93 -0.4 2.58e-6 Obesity-related traits; TGCT cis rs492146 0.765 rs622902 chr6:52846474 G/A cg06706454 chr6:52930286 FBXO9 -0.53 -4.95 -0.41 2.36e-6 Epilepsy (remission after treatment); TGCT cis rs8078723 1.000 rs4795418 chr17:38164851 T/C cg17467752 chr17:38218738 THRA 0.54 5.22 0.42 7.25e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs7617773 0.817 rs6791930 chr3:48329900 A/G cg11946769 chr3:48343235 NME6 0.74 6.34 0.49 3.97e-9 Coronary artery disease; TGCT cis rs981844 1.000 rs2251994 chr4:154654097 C/T cg14289246 chr4:154710475 SFRP2 1.02 8.53 0.61 4.35e-14 Response to statins (LDL cholesterol change); TGCT cis rs1005277 0.579 rs2474587 chr10:38420666 C/T cg13531842 chr10:38383804 ZNF37A -0.38 -4.55 -0.38 1.25e-5 Extrinsic epigenetic age acceleration; TGCT cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg05985448 chr10:134359359 INPP5A 0.22 4.75 0.39 5.54e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1915146 0.967 rs7086481 chr10:126844523 A/T cg05090351 chr10:126851162 NA -0.43 -4.96 -0.41 2.25e-6 Menarche (age at onset); TGCT cis rs2535633 0.602 rs6801235 chr3:53009595 T/C cg11645453 chr3:52864694 ITIH4 0.25 4.66 0.39 8.13e-6 Body mass index; TGCT cis rs910316 1.000 rs910316 chr14:75626042 A/C cg23033748 chr14:75592666 NEK9 0.28 4.77 0.39 4.98e-6 Height; TGCT cis rs7809950 0.678 rs2237661 chr7:106863123 T/C cg23024343 chr7:107201750 COG5 -0.43 -5.91 -0.47 3.13e-8 Coronary artery disease; TGCT cis rs73110464 0.609 rs6580923 chr12:53358352 A/G cg05393297 chr12:53359155 NA -0.79 -8.43 -0.6 7.2e-14 Cancer (pleiotropy); TGCT cis rs11031096 0.655 rs34295904 chr11:4206701 C/A cg18678763 chr11:4115507 RRM1 -0.45 -5.84 -0.46 4.31e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs763121 0.853 rs5757208 chr22:39049230 A/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg08859206 chr1:53392774 SCP2 0.4 6.05 0.48 1.58e-8 Monocyte count; TGCT cis rs7439150 1.000 rs1800790 chr4:155483708 G/A cg22130008 chr4:155548532 NA -0.48 -5.91 -0.47 3.02e-8 Fibrinogen levels; TGCT cis rs13256369 0.802 rs35382339 chr8:8559255 G/A cg17143192 chr8:8559678 CLDN23 0.54 4.86 0.4 3.53e-6 Obesity-related traits; TGCT cis rs2204008 0.682 rs2320517 chr12:38259239 A/T cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Bladder cancer; TGCT cis rs1401999 0.674 rs562 chr3:183637845 T/C cg01324343 chr3:183735012 ABCC5 0.73 8.93 0.63 4.76e-15 Anterior chamber depth; TGCT cis rs1385374 0.858 rs11059933 chr12:129303593 T/C cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs10504229 1.000 rs59708460 chr8:58196526 G/A cg24829409 chr8:58192753 C8orf71 -0.55 -4.74 -0.39 5.83e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs4472144 chr4:98956494 G/A cg05340658 chr4:99064831 C4orf37 0.53 6.02 0.48 1.8e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1670533 1.000 rs13107058 chr4:1054379 G/A cg27284194 chr4:1044797 NA 0.69 5.71 0.46 7.76e-8 Recombination rate (females); TGCT trans rs1005277 0.579 rs2474587 chr10:38420666 C/T cg27523141 chr10:43048294 ZNF37B 0.72 8.36 0.6 1.09e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7100689 0.784 rs4258322 chr10:82184770 T/C cg01528321 chr10:82214614 TSPAN14 0.9 9.42 0.65 3.22e-16 Post bronchodilator FEV1; TGCT cis rs6728642 0.803 rs11891458 chr2:97632450 G/T cg26665480 chr2:98280029 ACTR1B -0.91 -5.94 -0.47 2.67e-8 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs6495367 1.000 rs6495367 chr15:79375347 C/T cg17916960 chr15:79447300 NA 0.34 4.82 0.4 4.08e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs4727027 0.901 rs1137432 chr7:148801658 C/T cg23583168 chr7:148888333 NA -0.72 -9.11 -0.63 1.8e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6121246 0.609 rs2149281 chr20:30417918 G/A cg13852791 chr20:30311386 BCL2L1 0.77 7.01 0.53 1.34e-10 Mean corpuscular hemoglobin; TGCT cis rs2562456 0.793 rs627522 chr19:21495804 C/T cg01304269 chr19:21688519 ZNF429 0.54 4.45 0.37 1.87e-5 Pain; TGCT cis rs3741404 0.594 rs11231704 chr11:63898182 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.68 -5.92 -0.47 2.88e-8 Platelet count; TGCT cis rs694739 1.000 rs499425 chr11:64105929 A/G cg02228329 chr11:64053129 BAD;GPR137 -0.78 -7.87 -0.58 1.54e-12 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs10832963 1.000 rs10832962 chr11:18656271 C/T cg09201001 chr11:18656081 SPTY2D1 1.04 11.77 0.73 6.2e-22 Breast cancer; TGCT cis rs7267979 1.000 rs2257808 chr20:25266450 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7681440 0.904 rs6532192 chr4:90764131 G/A cg26578617 chr4:90757533 SNCA -0.49 -5.1 -0.42 1.26e-6 Dementia with Lewy bodies; TGCT cis rs1008375 0.932 rs4698626 chr4:17605821 G/C cg18681998 chr4:17616180 MED28 0.98 10.43 0.68 1.17e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4268898 0.722 rs7564420 chr2:24414002 C/T cg02683114 chr2:24398427 C2orf84 -0.2 -4.89 -0.4 3.01e-6 Asthma; TGCT cis rs2228479 0.867 rs17784386 chr16:89947457 A/G cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs9396146 0.609 rs3734672 chr6:13787578 C/T cg25000576 chr6:13769806 NA 0.35 4.56 0.38 1.21e-5 Yeast infection; TGCT cis rs2046867 0.818 rs62249862 chr3:72867949 G/C cg25664220 chr3:72788482 NA -0.56 -7.04 -0.53 1.16e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs892961 0.899 rs7222532 chr17:75413302 G/C cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs7547997 0.615 rs12038925 chr1:158319449 G/A cg03528325 chr1:158223921 CD1A 0.34 4.71 0.39 6.65e-6 QRS duration; TGCT cis rs1008375 1.000 rs2286771 chr4:17643848 G/A cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.66 -6.72 -0.52 5.84e-10 Intelligence (multi-trait analysis); TGCT cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs2836974 0.897 rs2836932 chr21:40546717 G/A cg06238570 chr21:40685208 BRWD1 0.73 6.66 0.51 8.12e-10 Cognitive function; TGCT cis rs769267 0.896 rs2074298 chr19:19377716 C/G cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs2153535 0.541 rs1414352 chr6:8485547 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7523050 0.642 rs12044219 chr1:109481236 T/C cg08274380 chr1:109419600 GPSM2 1.03 5.92 0.47 2.91e-8 Fat distribution (HIV); TGCT cis rs12681287 0.605 rs2953509 chr8:87343194 C/T cg27223183 chr8:87520930 FAM82B -0.9 -6.71 -0.52 6.12e-10 Caudate activity during reward; TGCT cis rs4660261 0.545 rs803682 chr1:44362623 G/A cg13606994 chr1:44402422 ARTN -0.42 -4.52 -0.38 1.44e-5 Intelligence (multi-trait analysis); TGCT cis rs2303745 0.589 rs891018 chr19:17396761 C/T cg02221750 chr19:17393354 ANKLE1 0.49 6.64 0.51 8.88e-10 Systemic lupus erythematosus; TGCT cis rs10986311 0.722 rs17315546 chr9:127148229 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.73 0.39 5.91e-6 Vitiligo; TGCT cis rs3858526 0.959 rs11039723 chr11:5956002 G/C cg05234568 chr11:5960015 NA -0.44 -4.5 -0.37 1.57e-5 DNA methylation (variation); TGCT cis rs7267979 0.932 rs367666 chr20:25449818 T/C cg16686733 chr20:25566563 NINL 0.56 5.61 0.45 1.26e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2730260 0.537 rs3793223 chr7:158863574 C/A cg09066883 chr7:157932951 PTPRN2 0.44 4.83 0.4 3.96e-6 Myopia (pathological); TGCT cis rs2895526 0.902 rs7077657 chr10:12668814 C/G cg18283737 chr10:12085149 UPF2 0.51 4.97 0.41 2.18e-6 Headache; TGCT cis rs9660180 0.846 rs10907195 chr1:1713348 C/T cg13866156 chr1:1669148 SLC35E2 0.2 4.44 0.37 1.94e-5 Body mass index; TGCT cis rs2066819 1.000 rs2306694 chr12:56680636 C/T cg26714650 chr12:56694279 CS 1.36 6.06 0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs854765 0.647 rs854814 chr17:18003648 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.71 7.41 0.55 1.72e-11 Total body bone mineral density; TGCT cis rs28595532 0.920 rs56227053 chr4:119772460 C/T cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs6121246 0.567 rs6088796 chr20:30213229 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs2180341 0.695 rs6569487 chr6:127726196 C/T cg27446573 chr6:127587934 RNF146 -0.74 -7.46 -0.56 1.28e-11 Breast cancer; TGCT cis rs2342371 0.848 rs5016648 chr3:196207989 A/G cg15048948 chr3:196158458 UBXN7 -0.54 -4.62 -0.38 9.56e-6 Fat distribution (HIV); TGCT cis rs9914544 1.000 rs8066385 chr17:18761133 C/T cg26378065 chr17:18585709 ZNF286B 0.52 4.73 0.39 5.94e-6 Educational attainment (years of education); TGCT cis rs875971 0.798 rs6460304 chr7:65964728 G/A cg11764359 chr7:65958608 NA 0.58 5.34 0.43 4.22e-7 Aortic root size; TGCT cis rs7772486 0.659 rs9376957 chr6:146011064 C/T cg23711669 chr6:146136114 FBXO30 -0.85 -9.45 -0.65 2.66e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg06481639 chr22:41940642 POLR3H 0.74 6.59 0.51 1.11e-9 Vitiligo; TGCT cis rs2688608 0.967 rs72814394 chr10:75656325 C/T cg02947784 chr10:75434997 AGAP5 0.16 4.56 0.38 1.21e-5 Inflammatory bowel disease; TGCT cis rs17270561 0.525 rs10484432 chr6:26008876 G/A cg17042849 chr6:26104293 HIST1H4C -0.81 -5.71 -0.46 7.76e-8 Iron status biomarkers; TGCT trans rs7613875 0.641 rs6793528 chr3:50100188 C/A cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT trans rs208520 0.690 rs12189780 chr6:66759619 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs10276381 0.786 rs10281102 chr7:28243473 A/G cg23620719 chr7:28220237 JAZF1 0.95 5.75 0.46 6.52e-8 Crohn's disease; TGCT cis rs597539 0.652 rs602805 chr11:68662076 A/T cg06028808 chr11:68637592 NA 0.51 6.62 0.51 9.55e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs709400 0.604 rs7158144 chr14:103887615 A/G cg26031613 chr14:104095156 KLC1 0.86 9.43 0.65 2.96e-16 Body mass index; TGCT cis rs9916302 0.861 rs3889368 chr17:37683231 C/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.92 -0.4 2.69e-6 Glomerular filtration rate (creatinine); TGCT cis rs709400 0.628 rs6575983 chr14:103869849 C/G cg26031613 chr14:104095156 KLC1 0.76 8.89 0.62 5.88e-15 Body mass index; TGCT cis rs1568889 0.838 rs10835273 chr11:28156598 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.01 0.7 4.33e-20 Bipolar disorder; TGCT cis rs861020 1.000 rs642961 chr1:209989270 A/G cg05527609 chr1:210001259 C1orf107 0.93 7.67 0.57 4.25e-12 Orofacial clefts; TGCT cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.791 rs1527516 chr4:98967937 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4689388 0.647 rs9997824 chr4:6283253 T/C cg14416269 chr4:6271139 WFS1 0.38 4.78 0.39 4.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs611744 0.967 rs686584 chr8:109192357 G/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs10464366 0.544 rs4540324 chr7:39185299 G/C cg18850127 chr7:39170497 POU6F2 0.33 7.18 0.54 5.5e-11 IgG glycosylation; TGCT cis rs853679 0.550 rs1233701 chr6:28168726 C/G cg12963246 chr6:28129442 ZNF389 -0.48 -4.85 -0.4 3.65e-6 Depression; TGCT cis rs3733585 0.673 rs4314284 chr4:9956096 C/T cg00071950 chr4:10020882 SLC2A9 -0.58 -6.98 -0.53 1.57e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs823143 0.570 rs823084 chr1:205798313 G/T cg26354017 chr1:205819088 PM20D1 0.55 6.66 0.51 7.98e-10 Monocyte percentage of white cells; TGCT trans rs2727020 0.688 rs2734002 chr11:49234162 A/G cg15704280 chr7:45808275 SEPT13 0.7 7.64 0.57 5e-12 Coronary artery disease; TGCT cis rs17331151 0.573 rs2276818 chr3:52864635 A/G cg27565382 chr3:53032988 SFMBT1 0.47 5.96 0.47 2.42e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9755467 0.539 rs4974430 chr3:127168018 A/T cg26017091 chr3:126748781 PLXNA1 0.19 4.63 0.38 9.18e-6 Educational attainment (years of education); TGCT cis rs6964587 1.000 rs7806157 chr7:91601930 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg07157834 chr1:205819609 PM20D1 0.42 6.7 0.52 6.47e-10 Menarche (age at onset); TGCT cis rs892961 1.000 rs11653743 chr17:75401923 C/A cg05865280 chr17:75406074 SEPT9 0.29 6.82 0.52 3.6e-10 Airflow obstruction; TGCT cis rs77633900 0.614 rs280008 chr15:77011815 T/C cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs6570726 0.905 rs377143 chr6:145834220 C/T cg23711669 chr6:146136114 FBXO30 0.67 6.05 0.48 1.58e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs4689388 0.782 rs4262051 chr4:6281775 G/A cg14416269 chr4:6271139 WFS1 0.4 5.13 0.42 1.07e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs13108904 0.967 rs900029 chr4:1279145 C/T cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs67478160 0.595 rs2295146 chr14:104199356 C/T cg26031613 chr14:104095156 KLC1 -0.74 -7.51 -0.56 9.92e-12 Schizophrenia; TGCT cis rs12289510 1.000 rs12289510 chr11:124947051 C/T cg03868193 chr11:124958746 SLC37A2 0.36 4.73 0.39 6.1e-6 Platelet-derived growth factor BB levels; TGCT cis rs2249625 0.545 rs2463746 chr6:72876954 C/G cg08500200 chr6:72892038 RIMS1 -0.42 -4.54 -0.38 1.33e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs4665809 1.000 rs4665306 chr2:26319124 C/T cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs8017423 0.935 rs17188598 chr14:90722473 A/T cg04374321 chr14:90722782 PSMC1 0.76 7.69 0.57 3.88e-12 Mortality in heart failure; TGCT cis rs7567389 0.599 rs6430938 chr2:128162623 A/G cg02161262 chr2:127865248 BIN1 -0.51 -4.6 -0.38 1.01e-5 Self-rated health; TGCT cis rs6089584 1.000 rs3787425 chr20:60559256 C/T cg16423285 chr20:60520624 NA -0.52 -5.45 -0.44 2.6e-7 Body mass index; TGCT cis rs2549003 1.000 rs2070725 chr5:131821788 C/T cg00255919 chr5:131827918 IRF1 0.2 4.65 0.39 8.22e-6 Asthma (sex interaction); TGCT trans rs28735056 0.967 rs498541 chr18:77589655 G/A cg05926928 chr17:57297772 GDPD1 -0.71 -7.64 -0.57 5.03e-12 Schizophrenia; TGCT cis rs7267979 0.844 rs6083851 chr20:25401235 G/A cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs586688 0.625 rs688122 chr1:201653344 T/C cg07139329 chr1:201708558 NAV1 -0.52 -5.29 -0.43 5.27e-7 Obesity-related traits; TGCT cis rs2760061 0.583 rs1745413 chr1:228212456 A/G cg02753203 chr1:228287806 NA 0.39 7.91 0.58 1.2e-12 Diastolic blood pressure; TGCT cis rs459571 0.920 rs2520094 chr9:136919985 A/T cg13789015 chr9:136890014 NCRNA00094 0.37 6.32 0.49 4.31e-9 Platelet distribution width; TGCT cis rs6845621 0.870 rs1377150 chr4:18922754 C/G cg12196642 chr4:18937545 NA 0.26 4.64 0.38 8.81e-6 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs1552244 0.816 rs9847657 chr3:10173492 G/T cg00149659 chr3:10157352 C3orf10 0.79 5.58 0.45 1.41e-7 Alzheimer's disease; TGCT cis rs4812048 0.793 rs62205397 chr20:57597011 C/T cg24457521 chr20:57607420 ATP5E -0.7 -4.64 -0.38 8.78e-6 Mean platelet volume; TGCT cis rs2288884 1.000 rs2288884 chr19:52532271 C/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.6 -0.38 1.03e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs12950390 0.853 rs11655336 chr17:45858836 A/G cg24803719 chr17:45855879 NA 0.5 5.19 0.42 8.41e-7 IgG glycosylation; TGCT cis rs2463822 1.000 rs72921501 chr11:62115622 A/T cg06239285 chr11:62104954 ASRGL1 -0.94 -6.62 -0.51 9.63e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7582180 0.614 rs1530031 chr2:101009326 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.77 -0.39 5.18e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs2167892 chr4:99048503 G/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2153535 0.580 rs6937186 chr6:8494493 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1372520 0.684 rs2737030 chr4:90710099 C/T cg20003494 chr4:90757398 SNCA -0.6 -4.83 -0.4 3.89e-6 Neuroticism; TGCT cis rs4843747 0.671 rs28671027 chr16:88116323 G/A cg06915872 chr16:87998081 BANP -0.3 -4.57 -0.38 1.14e-5 Menopause (age at onset); TGCT cis rs11578119 1.000 rs11578119 chr1:170501456 C/T cg09767346 chr1:170501363 GORAB 0.64 5.11 0.42 1.16e-6 Male-pattern baldness; TGCT cis rs7647973 0.626 rs62260723 chr3:49872124 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 -0.34 -4.51 -0.38 1.5e-5 Menarche (age at onset); TGCT cis rs9644031 1 rs9644031 chr8:23359280 C/A cg00472375 chr8:23315376 ENTPD4 0.61 4.53 0.38 1.37e-5 Mean corpuscular volume; TGCT cis rs9650657 0.501 rs3021500 chr8:11023997 G/C cg21775007 chr8:11205619 TDH -0.56 -5.28 -0.43 5.59e-7 Neuroticism; TGCT cis rs2760061 0.583 rs1774757 chr1:228211135 C/G cg02753203 chr1:228287806 NA 0.39 7.85 0.58 1.67e-12 Diastolic blood pressure; TGCT cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.61 0.51 1.01e-9 Bipolar disorder; TGCT cis rs7917772 0.505 rs61869211 chr10:104449836 A/G cg05855489 chr10:104503620 C10orf26 -0.68 -5.57 -0.45 1.52e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9611565 0.694 rs5751107 chr22:41857812 A/G cg17554472 chr22:41940697 POLR3H 0.48 4.95 0.41 2.39e-6 Vitiligo; TGCT cis rs478304 0.593 rs9666878 chr11:65475816 A/C cg27068330 chr11:65405492 SIPA1 0.97 10.59 0.69 4.53e-19 Acne (severe); TGCT cis rs10504229 1.000 rs72652905 chr8:58188355 A/G cg24829409 chr8:58192753 C8orf71 -0.57 -5.35 -0.43 4.03e-7 Developmental language disorder (linguistic errors); TGCT cis rs11167764 0.945 rs13161849 chr5:141473395 A/G cg23435118 chr5:141488016 NDFIP1 -0.28 -4.58 -0.38 1.1e-5 Crohn's disease; TGCT cis rs7769051 0.522 rs7738256 chr6:133113066 C/G cg22852734 chr6:133119734 C6orf192 1.23 4.59 0.38 1.06e-5 Type 2 diabetes nephropathy; TGCT cis rs10464366 1.000 rs10951593 chr7:39121390 C/T cg18850127 chr7:39170497 POU6F2 0.23 5.03 0.41 1.66e-6 IgG glycosylation; TGCT cis rs4494114 1.000 rs4607833 chr1:39354272 G/C cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.1e-9 Blood protein levels; TGCT cis rs12368653 0.666 rs799267 chr12:58113158 C/T cg12615879 chr12:58013172 SLC26A10 0.49 5.89 0.47 3.39e-8 Multiple sclerosis; TGCT cis rs9457247 1.000 rs439553 chr6:167391212 A/G cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg20637647 chr7:64974828 NA 0.96 5.59 0.45 1.41e-7 Diabetic kidney disease; TGCT cis rs644799 1.000 rs12786522 chr11:95522858 G/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.51 0.61 4.7e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12291225 0.585 rs10832246 chr11:14380828 G/A cg19336497 chr11:14380999 RRAS2 -0.44 -7.14 -0.54 6.96e-11 Sense of smell; TGCT trans rs8073060 0.586 rs225294 chr17:33925762 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.04 -0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg21951975 chr1:209979733 IRF6 0.69 5.63 0.45 1.16e-7 Cleft lip with or without cleft palate; TGCT cis rs10992471 0.598 rs7867300 chr9:95183107 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.52 4.81 0.4 4.32e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3793683 1.000 rs3793683 chr10:134568387 G/T cg27286337 chr10:134555280 INPP5A -0.46 -7.29 -0.55 3.16e-11 Migraine; TGCT cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg08280861 chr8:58055591 NA 0.38 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.897 rs13052882 chr21:40555351 G/C cg11644478 chr21:40555479 PSMG1 1.03 10.32 0.68 2.12e-18 Cognitive function; TGCT cis rs6933660 0.720 rs6936936 chr6:151753395 A/G cg14262678 chr6:151773367 RMND1;C6orf211 0.5 4.76 0.39 5.36e-6 Menarche (age at onset); TGCT cis rs6490294 0.747 rs7978068 chr12:112501766 T/G cg10833066 chr12:111807467 FAM109A 0.37 5.44 0.44 2.68e-7 Mean platelet volume; TGCT cis rs4713118 0.588 rs200994 chr6:27813813 A/C cg18675097 chr6:28227127 NKAPL 0.37 4.69 0.39 7.13e-6 Parkinson's disease; TGCT cis rs4808199 0.947 rs4808960 chr19:19574277 G/C cg03709012 chr19:19516395 GATAD2A 1.0 7.8 0.57 2.23e-12 Nonalcoholic fatty liver disease; TGCT cis rs6003958 1 rs6003958 chr22:24264089 T/G cg18538332 chr22:24372958 LOC391322 0.89 7.91 0.58 1.21e-12 S-phenylmercapturic acid levels in smokers; TGCT cis rs7618915 0.570 rs4687633 chr3:52630548 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs5750830 0.594 rs5757648 chr22:39775156 G/A cg05872129 chr22:39784769 NA -0.84 -8.83 -0.62 8.39e-15 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.559 rs376633 chr6:88042785 T/C cg04972856 chr6:88032051 C6orf162;GJB7 0.41 4.81 0.4 4.22e-6 Monocyte percentage of white cells; TGCT cis rs6121246 0.909 rs1994251 chr20:30287328 T/G cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs12049351 0.665 rs6663689 chr1:229630163 C/T cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs2688608 0.620 rs11000767 chr10:75516626 G/T cg19442545 chr10:75533431 FUT11 -0.36 -5.74 -0.46 6.99e-8 Inflammatory bowel disease; TGCT cis rs12477438 0.798 rs12477754 chr2:99628073 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs1008375 1.000 rs13149474 chr4:17688582 G/A cg16339924 chr4:17578868 LAP3 -0.61 -4.81 -0.4 4.33e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2204008 0.777 rs8189597 chr12:38307739 G/C cg26384229 chr12:38710491 ALG10B -0.81 -7.05 -0.53 1.13e-10 Bladder cancer; TGCT cis rs8177253 0.965 rs4854762 chr3:133499063 A/G cg16414030 chr3:133502952 NA 0.6 9.35 0.64 4.64e-16 Iron status biomarkers; TGCT cis rs7772486 0.875 rs9399573 chr6:146403255 A/T cg05347473 chr6:146136440 FBXO30 0.55 5.14 0.42 1.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs877529 0.625 rs714016 chr22:39532554 G/T cg18708252 chr22:39545030 CBX7 0.35 5.1 0.42 1.23e-6 Multiple myeloma; TGCT cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg10802521 chr3:52805072 NEK4 -0.8 -9.8 -0.66 3.79e-17 Bipolar disorder; TGCT cis rs13401104 0.587 rs7581196 chr2:237151098 A/C cg19324714 chr2:237145437 ASB18 -0.46 -4.88 -0.4 3.17e-6 Educational attainment; TGCT cis rs5769707 0.681 rs8137111 chr22:50043750 G/A cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 4.99e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7666738 0.800 rs7683737 chr4:99070880 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2410601 0.503 rs7843518 chr8:18925159 C/T cg19414122 chr8:18896631 NA -0.27 -4.51 -0.38 1.51e-5 Urinary albumin excretion rate in type 1 diabetes; TGCT cis rs2688608 0.618 rs28553894 chr10:75489843 C/A cg15838173 chr10:75533400 FUT11 -0.31 -5.16 -0.42 9.66e-7 Inflammatory bowel disease; TGCT cis rs554111 1.000 rs554111 chr1:21042300 C/G cg08890418 chr1:21044141 KIF17 0.57 6.03 0.48 1.73e-8 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs11718455 1.000 rs28731098 chr3:44019816 A/C cg08738300 chr3:44038990 NA 0.88 6.65 0.51 8.52e-10 Coronary artery disease; TGCT trans rs4332037 0.539 rs55993248 chr7:2071132 A/G cg25206134 chr2:45395956 NA 0.97 7.42 0.55 1.6e-11 Bipolar disorder; TGCT cis rs9611565 1.000 rs5751086 chr22:41768862 C/T cg06634786 chr22:41940651 POLR3H -0.63 -6.07 -0.48 1.46e-8 Vitiligo; TGCT cis rs1218582 0.710 rs7553195 chr1:154837796 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.68 -6.73 -0.52 5.48e-10 Prostate cancer; TGCT cis rs9467773 1.000 rs10946834 chr6:26533664 G/C cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs9733 0.744 rs3754211 chr1:150951857 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 5.02 0.41 1.74e-6 Tonsillectomy; TGCT cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs2012796 0.956 rs6574646 chr14:81819809 A/G cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs68170813 0.559 rs3823960 chr7:107009349 T/C cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs9295536 0.620 rs6915330 chr6:22136172 C/G cg25792714 chr6:21666554 FLJ22536 -0.52 -4.72 -0.39 6.22e-6 Neuroblastoma; TGCT cis rs2204008 0.576 rs11519979 chr12:37999413 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs8141529 0.702 rs469992 chr22:29314899 T/C cg02153584 chr22:29168773 CCDC117 -0.62 -4.89 -0.4 3.05e-6 Lymphocyte counts; TGCT cis rs2806561 0.606 rs218341 chr1:23294153 G/C cg12483005 chr1:23474871 LUZP1 0.41 5.27 0.43 5.89e-7 Height; TGCT cis rs66573146 1.000 rs66712119 chr4:6965428 A/T cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs7100689 0.784 rs6585986 chr10:82171559 T/C cg01528321 chr10:82214614 TSPAN14 0.94 9.82 0.66 3.45e-17 Post bronchodilator FEV1; TGCT cis rs4517514 0.509 rs11018869 chr11:89865168 A/G cg14505434 chr11:89522851 NA 0.45 4.46 0.37 1.82e-5 Trans fatty acid levels; TGCT cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs916888 0.610 rs199453 chr17:44800946 C/T cg22433210 chr17:43662623 NA 0.94 8.08 0.59 4.8e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10875746 0.768 rs4760676 chr12:48421663 G/A cg20731937 chr12:48336164 NA 0.72 6.09 0.48 1.34e-8 Longevity (90 years and older); TGCT cis rs10927875 1.000 rs10927875 chr1:16299312 A/G cg22431228 chr1:16359049 CLCNKA -0.25 -4.55 -0.38 1.24e-5 Dilated cardiomyopathy; TGCT cis rs6089584 0.893 rs6089306 chr20:60574868 G/A cg16423285 chr20:60520624 NA -0.63 -6.97 -0.53 1.66e-10 Body mass index; TGCT cis rs798766 1.000 rs798741 chr4:1712413 A/G cg05874882 chr4:1763078 NA -0.36 -4.96 -0.41 2.28e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs9733 0.596 rs34600506 chr1:150687808 C/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs9653442 0.564 rs11902705 chr2:100795207 A/G cg22139774 chr2:100720529 AFF3 0.31 4.78 0.39 4.81e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs5757676 1.000 rs5757676 chr22:39841700 T/C cg24399712 chr22:39784796 NA -0.98 -8.16 -0.59 3.18e-13 IgG glycosylation; TGCT cis rs7552404 0.727 rs12122939 chr1:76276353 T/C cg10523679 chr1:76189770 ACADM 0.75 7.21 0.54 4.89e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs112591243 0.685 rs115448966 chr21:47988420 G/A cg10657630 chr21:48055338 PRMT2 1.0 5.29 0.43 5.4e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs2230307 0.536 rs6677998 chr1:100461046 G/A cg24955406 chr1:100503596 HIAT1 0.75 4.88 0.4 3.2e-6 Carotid intima media thickness; TGCT cis rs7523050 0.730 rs34182354 chr1:109416340 C/T cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs28595532 0.920 rs115446044 chr4:119754635 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs78366141 0.536 rs80239864 chr4:89698183 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.26 5.46 0.44 2.54e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs736408 0.545 rs6445529 chr3:52662722 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs4689592 0.554 rs3951346 chr4:7073321 C/T cg25660036 chr4:7070649 GRPEL1 -0.66 -5.82 -0.46 4.71e-8 Monocyte percentage of white cells; TGCT cis rs2046867 0.908 rs6771413 chr3:72790308 G/A cg25664220 chr3:72788482 NA -0.54 -6.8 -0.52 3.96e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs916888 0.821 rs199505 chr17:44859410 A/G cg17911788 chr17:44343683 NA 0.59 6.13 0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1862618 0.671 rs2591955 chr5:56244948 C/T cg24531977 chr5:56204891 C5orf35 0.69 7.29 0.55 3.25e-11 Initial pursuit acceleration; TGCT cis rs35306767 0.761 rs12773961 chr10:1013215 C/G cg18964960 chr10:1102726 WDR37 0.7 4.91 0.4 2.84e-6 Eosinophil percentage of granulocytes; TGCT cis rs748404 0.631 rs3809482 chr15:43661802 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs769267 0.965 rs2074550 chr19:19387743 A/C cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs9682041 1.000 rs9682041 chr3:170091902 C/T cg07589077 chr3:170072950 NA 0.3 4.54 0.38 1.3e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7772486 0.754 rs702319 chr6:146006117 T/C cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12497850 0.931 rs6791542 chr3:48787219 A/G cg07636037 chr3:49044803 WDR6 0.95 10.62 0.69 3.95e-19 Parkinson's disease; TGCT cis rs8067545 0.967 rs4924801 chr17:19921070 T/C cg13482628 chr17:19912719 NA 0.56 4.82 0.4 4.18e-6 Schizophrenia; TGCT cis rs763014 0.966 rs7185390 chr16:666382 A/G cg07343612 chr16:622815 PIGQ -0.42 -8.39 -0.6 9.08e-14 Height; TGCT cis rs17253792 0.822 rs79024594 chr14:56092997 T/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs594074 0.951 rs559443 chr6:6558928 A/G cg03251356 chr6:7151709 RREB1 -0.37 -4.85 -0.4 3.62e-6 Diabetic kidney disease; TGCT cis rs7772486 0.686 rs6570701 chr6:145954090 A/G cg23711669 chr6:146136114 FBXO30 0.85 9.48 0.65 2.33e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.931 rs7283569 chr21:40644062 T/G cg17971929 chr21:40555470 PSMG1 0.98 9.61 0.65 1.14e-16 Cognitive function; TGCT cis rs1577917 0.740 rs7775864 chr6:86247759 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.54 4.87 0.4 3.29e-6 Response to antipsychotic treatment; TGCT cis rs9653442 0.511 rs6739695 chr2:100859622 A/G cg07810366 chr2:100720526 AFF3 -0.4 -6.08 -0.48 1.35e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11673344 0.503 rs1667370 chr19:37490220 A/T cg08039142 chr19:36980659 ZNF566 0.56 5.24 0.43 6.67e-7 Obesity-related traits; TGCT cis rs801193 1.000 rs4717319 chr7:66242593 A/G cg18876405 chr7:65276391 NA 0.34 5.06 0.41 1.5e-6 Aortic root size; TGCT cis rs7809950 1.000 rs2178497 chr7:107278901 T/C cg23024343 chr7:107201750 COG5 0.34 5.3 0.43 5.01e-7 Coronary artery disease; TGCT cis rs362272 0.505 rs10155132 chr4:3369500 A/G cg18352616 chr4:3374830 RGS12 0.24 5.02 0.41 1.76e-6 Serum sulfate level; TGCT cis rs10501293 0.746 rs1565252 chr11:43009119 A/C cg03447554 chr11:43094025 NA 0.44 6.25 0.49 5.97e-9 Cognitive performance; TGCT cis rs13118159 0.550 rs10016557 chr4:1363628 C/T cg05025164 chr4:1340916 KIAA1530 -0.75 -6.57 -0.51 1.23e-9 Longevity; TGCT cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.67 -7.32 -0.55 2.74e-11 Blood metabolite levels; TGCT cis rs2180341 0.920 rs1073931 chr6:127681762 A/T cg27446573 chr6:127587934 RNF146 1.14 10.91 0.7 7.51e-20 Breast cancer; TGCT cis rs6831352 0.918 rs13133633 chr4:100058697 C/G cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Vitiligo; TGCT cis rs12681288 0.862 rs4735981 chr8:1018437 A/C cg04851639 chr8:1020857 NA -0.37 -6.77 -0.52 4.49e-10 Schizophrenia; TGCT cis rs7804356 1.000 rs3801840 chr7:26832986 A/G cg03456212 chr7:26904342 SKAP2 -0.63 -4.78 -0.39 4.84e-6 Type 1 diabetes; TGCT cis rs10037670 0.530 rs59459154 chr5:153819672 G/A cg21964928 chr5:153872958 NA 0.25 4.49 0.37 1.63e-5 Behavioural disinhibition (generation interaction); TGCT cis rs7635838 0.892 rs9814907 chr3:11438645 G/A cg00170343 chr3:11313890 ATG7 0.65 6.26 0.49 5.79e-9 HDL cholesterol; TGCT cis rs9915657 0.660 rs12602039 chr17:70089384 A/G cg06234051 chr17:70120541 SOX9 -0.25 -5.13 -0.42 1.1e-6 Thyroid hormone levels; TGCT cis rs2153535 0.580 rs6926759 chr6:8456176 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6815814 0.950 rs5743794 chr4:38832727 C/T cg02016764 chr4:38805732 TLR1 -0.32 -4.91 -0.4 2.75e-6 Breast cancer; TGCT cis rs853679 0.546 rs200949 chr6:27835435 A/G cg10876282 chr6:28092338 ZSCAN16 0.75 4.45 0.37 1.88e-5 Depression; TGCT cis rs2456568 0.775 rs1607404 chr11:93660449 C/G cg16099599 chr11:93583650 C11orf90 -0.39 -4.57 -0.38 1.15e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10779751 0.762 rs1074078 chr1:11326788 C/T cg08854313 chr1:11322531 MTOR -0.82 -8.61 -0.61 2.7e-14 Body mass index; TGCT cis rs875971 0.662 rs448725 chr7:65514628 A/G cg18876405 chr7:65276391 NA 0.33 4.95 0.41 2.39e-6 Aortic root size; TGCT cis rs3617 0.573 rs2336668 chr3:52919096 G/T cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.92 0.4 2.69e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10186029 0.676 rs10187830 chr2:213964796 C/G cg08319019 chr2:214017104 IKZF2 0.62 5.76 0.46 6.13e-8 Systemic sclerosis; TGCT cis rs12580194 0.593 rs7971053 chr12:55729947 A/C cg10672482 chr12:55725839 OR6C3 -0.56 -4.89 -0.4 3.1e-6 Cancer; TGCT cis rs909674 0.690 rs5750823 chr22:39829973 C/T cg01416388 chr22:39784598 NA -0.74 -6.78 -0.52 4.37e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs36051895 0.623 rs3780382 chr9:5232299 G/A cg02405213 chr9:5042618 JAK2 -0.68 -7.9 -0.58 1.3e-12 Pediatric autoimmune diseases; TGCT cis rs4975709 0.589 rs1684967 chr5:1863055 G/C cg04156016 chr5:1868137 NA 0.31 4.46 0.37 1.81e-5 Cardiovascular disease risk factors; TGCT cis rs13256369 0.851 rs13249700 chr8:8563637 C/T cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs244731 0.959 rs9313752 chr5:176645435 G/T cg06060754 chr5:176797920 RGS14 -0.47 -6.4 -0.5 2.86e-9 Urate levels in lean individuals; TGCT cis rs7104764 1.000 rs2293167 chr11:211644 A/G cg18336825 chr11:236787 PSMD13;SIRT3 -1.02 -10.54 -0.69 6.26e-19 Menarche (age at onset); TGCT cis rs9858542 0.537 rs34915642 chr3:49358646 G/A cg00383909 chr3:49044727 WDR6 0.71 4.89 0.4 3.09e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2729354 0.768 rs2581922 chr11:57265400 C/T cg24343310 chr11:57249947 NA 0.28 4.67 0.39 7.56e-6 Blood protein levels; TGCT cis rs9611565 0.625 rs12483991 chr22:41935285 A/G cg17554472 chr22:41940697 POLR3H -0.48 -5.37 -0.43 3.71e-7 Vitiligo; TGCT cis rs12711979 1.000 rs6542655 chr2:3872434 T/C cg17052675 chr2:3827356 NA -0.32 -5.85 -0.46 4.12e-8 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs10875746 0.855 rs12310999 chr12:48447658 A/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs7104764 1.000 rs10902114 chr11:246234 A/G cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs6748734 1.000 rs4675868 chr2:241828542 A/C cg04034577 chr2:241836375 C2orf54 -0.4 -6.32 -0.49 4.22e-9 Urinary metabolites; TGCT cis rs11250097 0.528 rs36043848 chr8:11309533 A/G cg01383082 chr8:11323474 FAM167A 0.29 4.84 0.4 3.78e-6 Neuroticism; TGCT cis rs6121246 0.909 rs6060633 chr20:30263317 G/T cg18721089 chr20:30220636 NA -0.42 -4.65 -0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs10791097 0.694 rs11222370 chr11:130744767 T/G cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs8016982 0.633 rs7141288 chr14:81710232 C/A cg01989461 chr14:81687754 GTF2A1 0.79 7.79 0.57 2.26e-12 Schizophrenia; TGCT cis rs112217694 1.000 rs61117475 chr4:104654578 C/A cg24090629 chr4:104641072 TACR3 -1.0 -5.19 -0.42 8.44e-7 Menarche (age at onset); TGCT cis rs9549367 0.713 rs3024757 chr13:113823186 G/T cg00898013 chr13:113819073 PROZ -0.52 -6.19 -0.49 7.89e-9 Platelet distribution width; TGCT cis rs9291683 0.679 rs2241483 chr4:10099831 A/G cg11266682 chr4:10021025 SLC2A9 -0.47 -5.45 -0.44 2.58e-7 Bone mineral density; TGCT cis rs7095607 0.777 rs10762191 chr10:69920031 C/A cg18986048 chr10:69913749 MYPN 0.41 4.48 0.37 1.66e-5 Lung function (FVC); TGCT cis rs7144547 0.803 rs8008602 chr14:81890171 T/A cg02996355 chr14:81879375 NA -0.78 -8.39 -0.6 9.44e-14 Prudent dietary pattern; TGCT cis rs4819052 0.918 rs34886433 chr21:46680538 G/C cg06618935 chr21:46677482 NA -0.42 -5.21 -0.42 7.76e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1552244 0.554 rs7638846 chr3:10048601 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.32 -4.71 -0.39 6.47e-6 Alzheimer's disease; TGCT cis rs736408 0.546 rs3733046 chr3:52621627 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -4.93 -0.4 2.62e-6 Bipolar disorder; TGCT cis rs9513593 1.000 rs2182954 chr13:99937082 A/G cg21788972 chr13:99853209 UBAC2 0.54 4.55 0.38 1.28e-5 Psoriasis; TGCT cis rs2766692 1.000 rs35788933 chr14:100743555 C/T cg14866419 chr14:100704911 YY1 0.57 4.54 0.38 1.3e-5 Electroencephalographic traits in alcoholism; TGCT cis rs10089 1.000 rs72794396 chr5:127501386 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.85 8.02 0.58 6.93e-13 Ileal carcinoids; TGCT cis rs360798 0.532 rs1022110 chr2:63046039 T/G cg17519650 chr2:63277830 OTX1 -0.64 -5.5 -0.44 2.07e-7 Coronary artery disease; TGCT cis rs10256972 0.669 rs10229964 chr7:1051776 A/G cg00431813 chr7:1051703 C7orf50 -0.26 -5.59 -0.45 1.35e-7 Longevity;Endometriosis; TGCT cis rs7209700 1.000 rs7209700 chr17:45351118 A/G cg21624342 chr17:45890973 OSBPL7 0.17 4.77 0.39 5.14e-6 IgG glycosylation; TGCT cis rs6882046 0.513 rs185291 chr5:88006764 T/C cg24804195 chr5:87968844 LOC645323 -0.61 -6.15 -0.48 9.97e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg13866156 chr1:1669148 SLC35E2 -0.23 -5.52 -0.44 1.9e-7 Body mass index; TGCT cis rs910316 0.523 rs4026175 chr14:75502240 C/A cg08847533 chr14:75593920 NEK9 0.72 6.82 0.52 3.54e-10 Height; TGCT cis rs9468199 0.510 rs72847322 chr6:27740054 C/T cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs17270561 1.000 rs12200962 chr6:25828986 T/C cg17042849 chr6:26104293 HIST1H4C -0.91 -6.17 -0.48 9.01e-9 Iron status biomarkers; TGCT cis rs35306767 0.855 rs11253468 chr10:903261 G/A cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs8180040 0.654 rs6773521 chr3:47234419 A/G cg27129171 chr3:47204927 SETD2 -0.7 -8.35 -0.6 1.13e-13 Colorectal cancer; TGCT cis rs2688608 0.967 rs1815076 chr10:75659886 C/T cg04320760 chr10:75533139 FUT11 -0.3 -4.57 -0.38 1.18e-5 Inflammatory bowel disease; TGCT cis rs2228479 0.850 rs62056061 chr16:89901767 G/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs7917772 0.582 rs4917973 chr10:104333700 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2836950 0.545 rs2836956 chr21:40623018 C/G cg11644478 chr21:40555479 PSMG1 0.52 4.84 0.4 3.77e-6 Menarche (age at onset); TGCT cis rs6882046 0.513 rs194225 chr5:88001186 A/G cg24804195 chr5:87968844 LOC645323 -0.59 -5.71 -0.46 7.88e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2228479 0.850 rs117675822 chr16:89919081 C/A cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs1215050 0.765 rs687795 chr4:98754912 C/G cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9916302 0.904 rs9944411 chr17:37483599 T/C cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs4654899 1.000 rs6689819 chr1:21472395 A/T cg01072550 chr1:21505969 NA -0.5 -8.07 -0.59 5.13e-13 Superior frontal gyrus grey matter volume; TGCT cis rs6840360 0.554 rs10222838 chr4:152690099 T/C cg17479576 chr4:152424074 FAM160A1 -0.52 -5.2 -0.42 8.05e-7 Intelligence (multi-trait analysis); TGCT cis rs11031096 0.683 rs55898672 chr11:4189284 G/C cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7017914 0.905 rs3110242 chr8:71932967 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs6969780 0.630 rs3735530 chr7:27189982 C/T cg04317399 chr7:27170313 HOXA4 -0.44 -4.9 -0.4 2.94e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs4148883 0.651 rs10020052 chr4:100086331 C/G cg12011299 chr4:100065546 ADH4 0.39 5.85 0.47 4.03e-8 Alcohol dependence; TGCT cis rs7267979 1.000 rs2500432 chr20:25290512 A/C cg16686733 chr20:25566563 NINL 0.6 6.15 0.48 9.59e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6089829 0.855 rs4809459 chr20:61661345 C/T cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs826838 1.000 rs1095575 chr12:39110284 C/G cg13010199 chr12:38710504 ALG10B -0.6 -4.85 -0.4 3.56e-6 Heart rate; TGCT trans rs804280 0.542 rs34117651 chr8:11791617 G/C cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Myopia (pathological); TGCT cis rs12765878 0.812 rs2475214 chr10:105660986 T/C cg11005552 chr10:105648138 OBFC1 -0.44 -7.29 -0.55 3.12e-11 Coronary artery disease; TGCT cis rs6088590 0.965 rs910869 chr20:33292777 C/T cg06115741 chr20:33292138 TP53INP2 0.67 5.77 0.46 5.93e-8 Coronary artery disease; TGCT cis rs896854 0.738 rs1713669 chr8:95958637 C/G cg23172400 chr8:95962367 TP53INP1 -0.36 -5.79 -0.46 5.33e-8 Type 2 diabetes; TGCT cis rs6141769 0.542 rs6057625 chr20:31304994 G/A cg13636640 chr20:31349939 DNMT3B -0.51 -4.48 -0.37 1.68e-5 Subjective well-being; TGCT cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg11502198 chr6:26597334 ABT1 -0.53 -4.93 -0.4 2.6e-6 Intelligence (multi-trait analysis); TGCT cis rs7178424 0.711 rs4283171 chr15:62172384 G/T cg00456672 chr15:62358751 C2CD4A -0.31 -4.72 -0.39 6.37e-6 Height; TGCT cis rs2204008 0.558 rs66545149 chr12:38204694 A/G cg26384229 chr12:38710491 ALG10B 0.78 6.56 0.51 1.32e-9 Bladder cancer; TGCT trans rs4083482 1.000 rs16927393 chr11:35375388 A/G cg12303247 chr1:155853542 SYT11 0.7 6.63 0.51 9.21e-10 Plasma omega-6 polyunsaturated fatty acid levels (adrenic acid); TGCT cis rs4711336 1.000 rs2296741 chr6:33659557 C/T cg14003231 chr6:33640908 ITPR3 0.29 4.7 0.39 6.79e-6 Height; TGCT cis rs1055129 0.655 rs7216615 chr17:73833910 T/C cg08125733 chr17:73851984 WBP2 0.52 4.68 0.39 7.51e-6 White matter hyperintensity burden; TGCT cis rs11190604 1.000 rs4919471 chr10:102299239 A/G cg23241863 chr10:102295624 HIF1AN 0.73 4.95 0.41 2.35e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7647973 0.516 rs12490393 chr3:49196132 C/T cg16497277 chr3:49208875 KLHDC8B -0.54 -5.2 -0.42 7.97e-7 Menarche (age at onset); TGCT cis rs7772486 0.686 rs6570705 chr6:145961201 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7824557 0.507 rs7010590 chr8:11062882 C/T cg21775007 chr8:11205619 TDH 0.52 5.15 0.42 1.01e-6 Retinal vascular caliber; TGCT cis rs11822910 0.911 rs2250887 chr11:57202184 G/A cg00522883 chr11:57194120 SLC43A3 0.32 4.58 0.38 1.1e-5 Platelet distribution width; TGCT cis rs73036520 0.846 rs17356664 chr19:45740771 C/T cg20198684 chr19:45742032 NA 0.28 5.32 0.43 4.78e-7 Monocyte percentage of white cells; TGCT cis rs1488864 1.000 rs10769689 chr11:6347116 A/T cg12755421 chr11:6342214 PRKCDBP -0.56 -4.57 -0.38 1.18e-5 Smooth-surface caries; TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.03 0.82 5.32e-32 Prudent dietary pattern; TGCT cis rs9948 0.655 rs57582887 chr2:97406354 A/C cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT cis rs9325144 0.647 rs11168104 chr12:38857616 G/T cg26384229 chr12:38710491 ALG10B -0.6 -5.49 -0.44 2.2e-7 Morning vs. evening chronotype; TGCT cis rs9291683 0.507 rs3775940 chr4:10025163 A/T cg00071950 chr4:10020882 SLC2A9 0.62 7.37 0.55 2.1e-11 Bone mineral density; TGCT cis rs6938 0.618 rs12912839 chr15:75221245 C/T cg10253484 chr15:75165896 SCAMP2 -0.57 -5.05 -0.41 1.53e-6 Breast cancer; TGCT cis rs1990950 0.605 rs4704863 chr5:156879727 C/T cg25387487 chr5:157003181 ADAM19 0.39 5.95 0.47 2.58e-8 Lung function (FEV1/FVC); TGCT cis rs12220777 1.000 rs11201660 chr10:81854531 A/G cg03267442 chr10:82210566 NA -0.38 -4.68 -0.39 7.54e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7223966 1.000 rs11079511 chr17:61858537 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1005277 0.579 rs1548255 chr10:38417193 T/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.52 -0.38 1.41e-5 Extrinsic epigenetic age acceleration; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg18538332 chr22:24372958 LOC391322 -0.98 -12.03 -0.73 1.42e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7698623 0.850 rs6532019 chr4:88768672 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.64 -0.38 8.7e-6 Cardiovascular disease risk factors; TGCT cis rs3733585 0.781 rs13103879 chr4:9972879 T/C cg00071950 chr4:10020882 SLC2A9 -0.63 -8.03 -0.58 6.51e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs3087591 0.639 rs2342052 chr17:29721011 T/C cg24425628 chr17:29625626 OMG;NF1 0.4 5.87 0.47 3.67e-8 Hip circumference; TGCT cis rs1552244 0.938 rs7625049 chr3:10115619 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs881375 0.967 rs7034492 chr9:123687211 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.12 0.42 1.14e-6 Rheumatoid arthritis; TGCT cis rs739401 0.527 rs418832 chr11:3072236 C/T cg05729581 chr11:3078854 CARS -0.57 -5.31 -0.43 4.86e-7 Longevity; TGCT cis rs853679 0.517 rs35193936 chr6:28076270 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs1552244 1.000 rs9811771 chr3:10133949 A/G cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs12039431 0.666 rs177347 chr1:37964322 G/C cg17933807 chr1:38061675 GNL2 -0.76 -7.21 -0.54 4.81e-11 Epithelial ovarian cancer; TGCT cis rs377070 0.966 rs368931 chr4:123631597 G/T cg10495464 chr4:123653540 BBS12;LOC729338 0.49 5.42 0.44 3.03e-7 Mosquito bite size; TGCT cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg11644478 chr21:40555479 PSMG1 -0.61 -5.74 -0.46 6.75e-8 Cognitive function; TGCT cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1371867 0.775 rs6511 chr8:101252680 T/C cg06002616 chr8:101225028 SPAG1 0.55 6.34 0.49 3.87e-9 Atrioventricular conduction; TGCT cis rs2652822 0.550 rs12593078 chr15:63517347 A/G cg12855773 chr15:63363890 TPM1 -0.17 -5.11 -0.42 1.16e-6 Metabolic traits; TGCT cis rs7267979 0.866 rs437635 chr20:25456888 A/G cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9457247 0.534 rs9356551 chr6:167400345 T/C cg23791538 chr6:167370224 RNASET2 0.61 6.02 0.48 1.85e-8 Crohn's disease; TGCT cis rs362272 0.524 rs2749781 chr4:3346617 T/C cg22655196 chr4:3374909 RGS12 0.26 5.21 0.42 7.55e-7 Serum sulfate level; TGCT cis rs68170813 0.559 rs2395880 chr7:107074264 A/G cg02696742 chr7:106810147 HBP1 -0.71 -5.9 -0.47 3.17e-8 Coronary artery disease; TGCT cis rs7772486 0.754 rs6937661 chr6:146113299 T/C cg23711669 chr6:146136114 FBXO30 -0.93 -10.49 -0.69 8.22e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs6050561 chr20:25334855 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1153858 0.621 rs2687512 chr15:45581495 T/C cg26924012 chr15:45694286 SPATA5L1 -1.0 -10.84 -0.7 1.12e-19 Homoarginine levels; TGCT cis rs4242434 0.819 rs6558167 chr8:22473850 T/C cg03733263 chr8:22462867 KIAA1967 1.07 16.48 0.83 4.9e-33 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs617219 0.698 rs7445125 chr5:78507417 A/G cg09550809 chr5:78407562 BHMT 0.41 5.7 0.46 8.14e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6430585 0.528 rs309161 chr2:136688749 A/G cg07169764 chr2:136633963 MCM6 -1.19 -11.63 -0.72 1.33e-21 Corneal structure; TGCT cis rs5167 0.566 rs60876330 chr19:45488133 C/T cg13119609 chr19:45449297 APOC2 0.24 4.64 0.38 8.62e-6 Blood protein levels; TGCT cis rs12220238 1.000 rs11000905 chr10:75925532 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs13315871 1.000 rs9844128 chr3:58391127 C/T cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg26338869 chr17:61819248 STRADA -0.57 -5.16 -0.42 9.43e-7 Prudent dietary pattern; TGCT cis rs295140 0.647 rs295132 chr2:201233502 A/G cg04283868 chr2:201171347 SPATS2L 0.53 5.16 0.42 9.63e-7 QT interval; TGCT cis rs9916302 0.652 rs9903269 chr17:37742383 A/T cg07936489 chr17:37558343 FBXL20 -0.7 -5.49 -0.44 2.21e-7 Glomerular filtration rate (creatinine); TGCT cis rs79057730 0.599 rs79272827 chr7:807015 C/G cg11064039 chr7:766100 PRKAR1B;HEATR2 0.75 5.67 0.45 9.59e-8 Initial pursuit acceleration; TGCT cis rs2576037 0.583 rs641366 chr18:44430326 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs7178572 0.524 rs11853287 chr15:77399371 A/G cg22256960 chr15:77711686 NA -0.85 -8.71 -0.62 1.61e-14 Type 2 diabetes; TGCT cis rs6964587 1.000 rs1859114 chr7:91682848 T/C cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs34638657 0.536 rs2967327 chr16:82188657 C/T cg09439754 chr16:82129088 HSD17B2 -0.22 -4.8 -0.4 4.55e-6 Lung adenocarcinoma; TGCT cis rs1691799 0.836 rs1184552 chr12:66756215 A/G cg16791601 chr12:66731901 HELB -0.29 -6.16 -0.48 9.12e-9 White blood cell count (basophil); TGCT cis rs4642101 0.662 rs3901664 chr3:12824660 T/C cg05775895 chr3:12838266 CAND2 0.92 11.15 0.71 2.02e-20 QRS complex (12-leadsum); TGCT trans rs4650994 0.525 rs2761463 chr1:178557137 T/C cg05059571 chr16:84539110 KIAA1609 0.52 10.34 0.68 1.86e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs8177253 1.000 rs8177253 chr3:133480192 A/G cg08048268 chr3:133502702 NA 0.65 9.81 0.66 3.64e-17 Iron status biomarkers; TGCT cis rs8031584 0.678 rs36047941 chr15:31159235 A/G cg08109568 chr15:31115862 NA -0.38 -5.03 -0.41 1.67e-6 Huntington's disease progression; TGCT cis rs12477438 0.734 rs4851184 chr2:99666434 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs669446 0.561 rs531459 chr1:44090675 T/C cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs4906332 1.000 rs34479426 chr14:103881823 G/C cg26031613 chr14:104095156 KLC1 -0.51 -4.63 -0.38 9.17e-6 Coronary artery disease; TGCT cis rs35934224 0.783 rs7284106 chr22:19857549 T/C cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT cis rs765787 0.530 rs28897155 chr15:45533974 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs7666738 0.753 rs4699604 chr4:99056353 T/C cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.9e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs3733585 0.699 rs6449171 chr4:9965998 C/T cg11266682 chr4:10021025 SLC2A9 0.56 7.45 0.56 1.37e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs67460515 1.000 rs67460515 chr3:161068566 T/C cg03342759 chr3:160939853 NMD3 -0.52 -5.38 -0.44 3.56e-7 Parkinson's disease; TGCT cis rs9814567 1.000 rs1138273 chr3:134261437 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.11 -0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs137603 0.644 rs470082 chr22:39715140 C/T cg17798944 chr22:39715225 SNORD43;RPL3 -0.66 -7.1 -0.54 8.7e-11 Primary biliary cholangitis; TGCT cis rs76878669 0.561 rs7125752 chr11:66162419 C/T cg18002602 chr11:66138449 SLC29A2 -0.54 -6.62 -0.51 9.59e-10 Educational attainment (years of education); TGCT cis rs7726839 0.540 rs57306627 chr5:597643 T/C cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs1568079 0.530 rs7070259 chr10:125243654 A/G cg04278168 chr10:124578263 NA -0.45 -4.64 -0.38 8.9e-6 Body mass index; TGCT cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs1048238 0.506 rs848209 chr1:16256007 T/C cg21385522 chr1:16154831 NA -0.58 -6.39 -0.5 3.09e-9 Systolic blood pressure; TGCT cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs916888 0.647 rs199523 chr17:44848517 C/A cg16520312 chr17:43971471 MAPT;LOC100128977 0.48 4.67 0.39 7.86e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6740322 0.748 rs6544636 chr2:43487486 C/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -5.81 -0.46 4.91e-8 Coronary artery disease; TGCT cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg03517284 chr6:25882590 NA -0.48 -4.78 -0.39 4.78e-6 Height; TGCT cis rs4268898 0.662 rs55661701 chr2:24400769 A/C cg02683114 chr2:24398427 C2orf84 -0.23 -4.56 -0.38 1.19e-5 Asthma; TGCT cis rs72387598 1 rs72387598 chr1:45922977 CAT/C cg05343316 chr1:45956843 TESK2 0.86 6.87 0.53 2.7e-10 Platelet distribution width; TGCT cis rs903263 0.965 rs12760594 chr1:84596910 C/T cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.73e-6 Breast cancer (male); TGCT cis rs1218582 0.688 rs58629129 chr1:154910930 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.64 -6.58 -0.51 1.21e-9 Prostate cancer; TGCT cis rs4975616 0.869 rs401681 chr5:1322087 C/T cg07493874 chr5:1342172 CLPTM1L -0.28 -6.64 -0.51 8.68e-10 Lung cancer; TGCT cis rs709400 0.663 rs17617941 chr14:103953032 T/C cg12935359 chr14:103987150 CKB -0.38 -5.78 -0.46 5.69e-8 Body mass index; TGCT cis rs2070997 0.517 rs9762 chr9:133762553 A/G cg01000188 chr9:133769184 QRFP 0.28 4.63 0.38 8.98e-6 Response to amphetamines; TGCT cis rs245880 0.740 rs245902 chr7:29194919 T/A cg17163760 chr7:29186267 CPVL -0.41 -5.08 -0.42 1.35e-6 Warfarin maintenance dose; TGCT cis rs28595532 0.920 rs116246794 chr4:119732491 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs9972944 0.756 rs7215462 chr17:63770498 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs1008375 0.931 rs10939734 chr4:17570709 C/T cg18681998 chr4:17616180 MED28 0.94 9.51 0.65 1.93e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7819412 0.745 rs6601569 chr8:11073578 C/T cg15556689 chr8:8085844 FLJ10661 -0.76 -7.35 -0.55 2.28e-11 Triglycerides; TGCT cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg13395646 chr4:1353034 KIAA1530 -0.39 -5.11 -0.42 1.19e-6 Longevity; TGCT cis rs854765 0.663 rs3183702 chr17:17747289 A/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.52 -0.38 1.43e-5 Total body bone mineral density; TGCT cis rs6952808 0.723 rs4721282 chr7:2025040 A/G cg22963979 chr7:1858916 MAD1L1 -0.43 -6.78 -0.52 4.36e-10 Bipolar disorder and schizophrenia; TGCT cis rs9653442 0.609 rs2576678 chr2:100704810 T/C cg07810366 chr2:100720526 AFF3 -0.43 -7.29 -0.55 3.26e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7523273 0.565 rs34355011 chr1:207887322 T/G cg22525895 chr1:207977042 MIR29B2 0.35 5.7 0.46 8.31e-8 Schizophrenia; TGCT cis rs9814567 0.762 rs13079012 chr3:134247706 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.83 6.48 0.5 1.99e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6088580 0.634 rs6088475 chr20:32964987 T/C cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs9868809 0.772 rs9883469 chr3:48719637 G/A cg15315015 chr3:49131774 QRICH1 0.98 4.65 0.38 8.53e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs10193935 0.892 rs7574609 chr2:42388468 C/A cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs10029849 chr4:99059362 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs4975616 0.686 rs37011 chr5:1348798 A/T cg07493874 chr5:1342172 CLPTM1L -0.26 -6.04 -0.48 1.65e-8 Lung cancer; TGCT cis rs909002 1.000 rs2292993 chr1:32140733 C/T cg11573219 chr1:32083031 HCRTR1 -0.4 -4.87 -0.4 3.32e-6 Intelligence (multi-trait analysis); TGCT cis rs9303401 0.614 rs35308719 chr17:57163501 C/T cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs6570726 0.905 rs419575 chr6:145840174 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9660180 0.967 rs6664664 chr1:1751264 G/A cg13866156 chr1:1669148 SLC35E2 -0.22 -5.23 -0.42 7.05e-7 Body mass index; TGCT cis rs2013441 0.965 rs8071665 chr17:20209943 T/C cg18979559 chr17:20280153 CCDC144C -0.49 -4.99 -0.41 1.97e-6 Obesity-related traits; TGCT cis rs2066819 1.000 rs11171803 chr12:56718422 T/C cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs2072499 0.778 rs41265025 chr1:156163906 C/T cg25208724 chr1:156163844 SLC25A44 1.01 9.29 0.64 6.58e-16 Testicular germ cell tumor; TGCT cis rs1008375 0.897 rs2315554 chr4:17660407 T/C cg10189774 chr4:17578691 LAP3 0.53 4.61 0.38 1e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2066819 1.000 rs76430365 chr12:56699993 A/C cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs10256972 0.577 rs4999286 chr7:1199506 C/G cg04025307 chr7:1156635 C7orf50 0.22 5.35 0.43 4.09e-7 Longevity;Endometriosis; TGCT cis rs28595532 0.920 rs115850161 chr4:119732447 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs748404 0.660 rs2439845 chr15:43722610 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs7599312 0.586 rs7565257 chr2:213388276 G/A cg16329650 chr2:213403929 ERBB4 0.55 4.62 0.38 9.45e-6 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10789491 0.951 rs35050319 chr1:47103886 C/A cg15501359 chr1:47185051 KIAA0494 -0.85 -8.33 -0.6 1.26e-13 Response to hepatitis C treatment; TGCT cis rs6570726 0.577 rs9497315 chr6:145791967 C/T cg13319975 chr6:146136371 FBXO30 0.64 5.69 0.46 8.55e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs10791097 0.592 rs4936122 chr11:130734264 A/C cg05962950 chr11:130786565 SNX19 0.9 11.39 0.72 5.2e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7829975 0.711 rs4841051 chr8:8685646 C/T cg15556689 chr8:8085844 FLJ10661 -0.69 -6.22 -0.49 6.86e-9 Mood instability; TGCT cis rs7914558 0.933 rs12763665 chr10:104653717 G/A cg04362960 chr10:104952993 NT5C2 0.58 5.16 0.42 9.65e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4689388 0.890 rs4689397 chr4:6299387 G/A cg25554036 chr4:6271136 WFS1 0.56 7.94 0.58 1.06e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7824557 0.767 rs7003241 chr8:11169075 A/G cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs3803170 0.513 rs10849946 chr12:111830485 C/G cg10833066 chr12:111807467 FAM109A -0.34 -5.36 -0.43 3.97e-7 Mean corpuscular hemoglobin; TGCT cis rs73001065 0.901 rs3794991 chr19:19610596 C/T cg03709012 chr19:19516395 GATAD2A 1.07 5.24 0.43 6.67e-7 LDL cholesterol; TGCT cis rs1008375 1.000 rs6811887 chr4:17640858 C/T cg16339924 chr4:17578868 LAP3 0.64 5.47 0.44 2.42e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1941023 0.503 rs4939349 chr11:60135880 G/A cg08716584 chr11:60157161 MS4A7 -0.31 -4.56 -0.38 1.21e-5 Congenital heart disease (maternal effect); TGCT cis rs7973719 0.833 rs11044332 chr12:7358768 C/A cg07052231 chr12:7363540 PEX5 0.37 5.74 0.46 6.97e-8 IgG glycosylation; TGCT cis rs6459788 0.527 rs6980250 chr7:157228710 C/T cg06271696 chr7:157225062 NA -0.35 -6.51 -0.5 1.65e-9 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT trans rs1814175 0.765 rs1794141 chr11:49914135 G/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs1532993 0.518 rs2174937 chr4:98552585 G/A cg05340658 chr4:99064831 C4orf37 -0.42 -5.05 -0.41 1.57e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9660180 0.839 rs12040826 chr1:1705287 A/C cg23982607 chr1:1823379 GNB1 -0.55 -8.57 -0.61 3.52e-14 Body mass index; TGCT cis rs6840360 0.615 rs7669465 chr4:152609289 C/T cg22705602 chr4:152727874 NA -0.31 -5.07 -0.41 1.41e-6 Intelligence (multi-trait analysis); TGCT cis rs10992471 0.580 rs7030920 chr9:95122952 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.5 -0.44 2.09e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1045714 0.895 rs4721867 chr7:2643352 A/G cg17215154 chr7:2644645 IQCE -0.27 -4.76 -0.39 5.19e-6 Urate levels in lean individuals; TGCT cis rs250677 0.617 rs166106 chr5:148447061 T/C cg18129178 chr5:148520854 ABLIM3 -0.42 -5.74 -0.46 6.77e-8 Breast cancer; TGCT cis rs208520 0.874 rs208491 chr6:66928459 C/G cg07460842 chr6:66804631 NA -0.94 -9.3 -0.64 6.32e-16 Exhaled nitric oxide output; TGCT cis rs2948294 0.588 rs7011221 chr8:8114246 C/T cg15462221 chr8:8086144 FLJ10661 -0.6 -5.11 -0.42 1.2e-6 Red cell distribution width; TGCT cis rs13064411 0.501 rs13092925 chr3:113209375 C/G cg18753928 chr3:113234510 CCDC52 -0.54 -4.58 -0.38 1.12e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs524023 0.957 rs893007 chr11:64365668 C/A cg07733098 chr11:64478343 NRXN2 0.32 4.83 0.4 3.9e-6 Urate levels in obese individuals; TGCT cis rs12532878 0.652 rs11768465 chr7:100198386 C/T cg19543017 chr7:100164136 AGFG2 -0.32 -4.71 -0.39 6.4e-6 Mean corpuscular hemoglobin; TGCT trans rs1814175 0.817 rs1851860 chr11:49861310 A/C cg15704280 chr7:45808275 SEPT13 -0.7 -8.0 -0.58 7.59e-13 Height; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg04234412 chr22:24373322 LOC391322 0.92 10.83 0.7 1.2e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6163 0.588 rs12763284 chr10:104508202 C/T cg22532475 chr10:104410764 TRIM8 -0.17 -4.54 -0.38 1.32e-5 Waist circumference;Hip circumference; TGCT cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg10047753 chr17:41438598 NA 0.77 7.43 0.56 1.52e-11 Menopause (age at onset); TGCT cis rs9611519 0.507 rs12484525 chr22:41443877 G/C cg13695892 chr22:41940480 POLR3H -0.58 -5.57 -0.45 1.52e-7 Neuroticism; TGCT cis rs112591243 0.685 rs117443865 chr21:47959731 C/G cg10657630 chr21:48055338 PRMT2 1.06 5.21 0.42 7.69e-7 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg21226059 chr5:178986404 RUFY1 0.62 7.13 0.54 7.36e-11 Lung cancer; TGCT cis rs2153535 0.580 rs9392220 chr6:8457946 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs524281 0.648 rs10896089 chr11:65936292 A/G cg00563793 chr11:65837595 PACS1 0.57 4.97 0.41 2.13e-6 Electroencephalogram traits; TGCT cis rs6748734 1.000 rs6751693 chr2:241837332 T/C cg04034577 chr2:241836375 C2orf54 -0.4 -6.3 -0.49 4.63e-9 Urinary metabolites; TGCT cis rs35146811 0.660 rs3779045 chr7:99779259 T/C cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs57994353 0.897 rs3812594 chr9:139368953 G/A cg13741927 chr9:139327495 INPP5E -0.24 -5.55 -0.45 1.66e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs13256369 0.951 rs13260947 chr8:8565883 A/G cg17143192 chr8:8559678 CLDN23 0.58 5.55 0.45 1.64e-7 Obesity-related traits; TGCT cis rs2832191 0.632 rs1984011 chr21:30337831 T/A cg08807101 chr21:30365312 RNF160 -0.63 -5.72 -0.46 7.47e-8 Dental caries; TGCT cis rs7584330 0.784 rs1463795 chr2:238412392 C/G cg14458575 chr2:238380390 NA -0.45 -6.77 -0.52 4.52e-10 Prostate cancer; TGCT cis rs10207060 0.500 rs4365487 chr2:240706803 T/C cg15726768 chr2:241314588 NA -0.32 -4.49 -0.37 1.63e-5 Obesity-related traits; TGCT cis rs7772486 0.875 rs9322048 chr6:146400439 A/G cg23711669 chr6:146136114 FBXO30 0.86 9.3 0.64 6.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs8077889 0.917 rs4793038 chr17:41916761 A/T cg26893861 chr17:41843967 DUSP3 1.06 12.21 0.74 5.35e-23 Triglycerides; TGCT cis rs7772486 0.790 rs2247666 chr6:146220409 C/A cg05347473 chr6:146136440 FBXO30 0.53 5.08 0.42 1.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs35306767 0.859 rs11817793 chr10:878895 C/T cg20503657 chr10:835505 NA 0.72 10.36 0.68 1.73e-18 Eosinophil percentage of granulocytes; TGCT cis rs2019137 0.936 rs4849169 chr2:113953657 A/C cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.56e-13 Lymphocyte counts; TGCT cis rs12908161 0.853 rs12912342 chr15:85248216 T/C cg11189052 chr15:85197271 WDR73 0.68 6.43 0.5 2.55e-9 Schizophrenia; TGCT cis rs734999 0.588 rs4648653 chr1:2535895 C/T cg18854424 chr1:2615690 NA 0.43 4.91 0.4 2.77e-6 Ulcerative colitis; TGCT cis rs9677476 0.657 rs11897387 chr2:232122576 T/C cg07929768 chr2:232055508 NA 0.32 5.08 0.41 1.38e-6 Food antigen IgG levels; TGCT cis rs7086627 0.515 rs1870147 chr10:82212541 A/T cg01528321 chr10:82214614 TSPAN14 0.67 6.36 0.5 3.61e-9 Post bronchodilator FEV1; TGCT cis rs3796352 1.000 rs11713290 chr3:52971579 G/A cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT trans rs1973993 0.567 rs2800431 chr1:97000998 C/T cg10631902 chr5:14652156 NA 0.37 9.49 0.65 2.22e-16 Weight; TGCT cis rs6733011 0.628 rs6713991 chr2:99464384 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -4.78 -0.39 4.78e-6 Bipolar disorder; TGCT cis rs11785400 0.731 rs9720504 chr8:143725502 T/C cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs765787 0.530 rs2554455 chr15:45521304 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.38 -0.43 3.63e-7 Uric acid levels; TGCT cis rs4455778 0.536 rs38770 chr7:48940586 A/G cg26309511 chr7:48887640 NA 0.46 5.51 0.44 1.98e-7 Lung cancer in never smokers; TGCT cis rs858239 0.539 rs2141305 chr7:23191899 T/C cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs10089 0.953 rs2016015 chr5:127527253 T/C cg19767477 chr5:127420684 SLC12A2 -0.43 -4.54 -0.38 1.3e-5 Ileal carcinoids; TGCT cis rs9916302 0.706 rs6503521 chr17:37715551 A/C cg03321784 chr17:37729644 NA -0.43 -4.55 -0.38 1.28e-5 Glomerular filtration rate (creatinine); TGCT cis rs7826238 0.623 rs2976893 chr8:8338219 G/T cg08975724 chr8:8085496 FLJ10661 -0.58 -5.52 -0.44 1.88e-7 Systolic blood pressure; TGCT trans rs2727020 0.576 rs10839305 chr11:49598733 T/C cg03929089 chr4:120376271 NA -0.76 -9.26 -0.64 7.66e-16 Coronary artery disease; TGCT cis rs2299587 0.554 rs2073567 chr8:17754034 G/A cg01800426 chr8:17659068 MTUS1 -0.58 -5.11 -0.42 1.18e-6 Economic and political preferences; TGCT cis rs797680 0.856 rs11164902 chr1:93778794 A/G cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6540559 0.546 rs59435160 chr1:210030730 C/A cg22029157 chr1:209979665 IRF6 0.84 6.31 0.49 4.44e-9 Cleft lip with or without cleft palate; TGCT cis rs875971 1.000 rs6979382 chr7:65886375 C/T cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs4523957 0.651 rs8068642 chr17:2060353 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9467773 1.000 rs9467797 chr6:26568473 A/T cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs4076764 0.846 rs12035840 chr1:163419177 G/C cg24596788 chr1:163392923 NA -0.17 -4.84 -0.4 3.8e-6 Motion sickness; TGCT cis rs7726839 0.540 rs61731455 chr5:665295 A/G cg09021430 chr5:549028 NA -0.4 -5.64 -0.45 1.08e-7 Obesity-related traits; TGCT cis rs3820068 0.608 rs12740492 chr1:16048951 A/T cg17385448 chr1:15911702 AGMAT 0.36 4.76 0.39 5.21e-6 Systolic blood pressure; TGCT cis rs7959452 0.590 rs11177644 chr12:69785748 A/G cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs614226 0.938 rs7972244 chr12:120994872 A/G cg01236616 chr12:121019343 POP5 1.26 13.2 0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT cis rs7703051 0.585 rs918623 chr5:74596682 A/C cg07671805 chr5:74907694 NA 0.49 4.46 0.37 1.84e-5 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs4776059 1.000 rs1863512 chr15:52959687 C/T cg25063058 chr15:52860530 ARPP19 0.54 4.79 0.4 4.6e-6 Schizophrenia; TGCT cis rs6912958 0.781 rs9450739 chr6:88268271 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs7772486 0.558 rs7753273 chr6:146066039 C/T cg13319975 chr6:146136371 FBXO30 0.73 6.55 0.51 1.36e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs17433780 0.523 rs6701673 chr1:89525812 C/G cg09516651 chr1:89888402 LOC400759 0.26 5.15 0.42 1.01e-6 Carotid intima media thickness; TGCT cis rs12220898 0.749 rs10776553 chr10:50482929 C/T cg06072769 chr10:50146962 WDFY4 0.38 5.15 0.42 1.02e-6 Inflammatory biomarkers; TGCT cis rs4925325 0.741 rs6142886 chr20:60511190 A/G cg12751644 chr20:60527061 NA 0.51 7.01 0.53 1.35e-10 Obesity-related traits; TGCT cis rs8141529 0.732 rs5997408 chr22:29207915 G/A cg02153584 chr22:29168773 CCDC117 0.68 5.9 0.47 3.31e-8 Lymphocyte counts; TGCT cis rs8067545 0.750 rs1421174 chr17:19950190 G/T cg13482628 chr17:19912719 NA 0.55 4.7 0.39 6.78e-6 Schizophrenia; TGCT cis rs12367572 0.965 rs11182706 chr12:45223339 T/C cg04608330 chr12:45269318 NELL2 -0.5 -4.68 -0.39 7.33e-6 Gut microbiome composition (summer); TGCT cis rs10875595 0.836 rs10067231 chr5:140673429 C/T cg20560182 chr5:140700478 TAF7 -0.64 -4.91 -0.4 2.76e-6 Pulmonary function decline; TGCT cis rs644799 0.710 rs11021311 chr11:95505227 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.81 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg03517284 chr6:25882590 NA 0.5 4.48 0.37 1.65e-5 Intelligence (multi-trait analysis); TGCT cis rs875971 1.000 rs6460292 chr7:65810075 G/A cg11764359 chr7:65958608 NA -0.61 -5.51 -0.44 1.96e-7 Aortic root size; TGCT cis rs4242434 0.927 rs11778693 chr8:22462852 T/C cg21658235 chr8:22456391 C8orf58 0.43 4.53 0.38 1.36e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs1552244 0.882 rs3755782 chr3:10029305 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs4494114 1.000 rs4491033 chr1:39352083 A/C cg25970120 chr1:39325951 RRAGC -0.53 -5.44 -0.44 2.72e-7 Blood protein levels; TGCT cis rs11122272 0.735 rs2808611 chr1:231548480 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.66 6.2 0.49 7.88e-9 Hemoglobin concentration; TGCT cis rs5769765 1.000 rs4597652 chr22:50270570 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs1008375 0.966 rs4698621 chr4:17587565 C/T cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 0.744 rs6050463 chr20:25208990 G/A cg03522245 chr20:25566470 NINL 0.53 5.3 0.43 5.01e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7513165 0.611 rs4951314 chr1:204152933 G/A cg12731349 chr1:204159619 KISS1 0.53 5.19 0.42 8.33e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs6988636 0.579 rs28528232 chr8:124189308 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs2637266 0.791 rs2395392 chr10:78359933 C/A cg18941641 chr10:78392320 NA 0.42 5.39 0.44 3.4e-7 Pulmonary function; TGCT cis rs8072100 0.713 rs4968228 chr17:45497548 T/C cg08085267 chr17:45401833 C17orf57 -0.51 -5.64 -0.45 1.11e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9929218 0.954 rs112225541 chr16:68755165 C/T cg01251360 chr16:68772225 CDH1 0.29 4.87 0.4 3.39e-6 Colorectal cancer; TGCT cis rs7312933 0.592 rs1551210 chr12:42865874 C/T cg19980929 chr12:42632907 YAF2 0.43 6.16 0.48 9.17e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6701037 0.681 rs13374887 chr1:175131962 A/T cg00321850 chr1:175162397 KIAA0040 0.44 6.03 0.48 1.7e-8 Alcohol dependence; TGCT cis rs798766 1.000 rs7682402 chr4:1743343 G/A cg05874882 chr4:1763078 NA -0.36 -4.83 -0.4 3.87e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs853679 0.517 rs9357063 chr6:28060005 G/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs698813 0.604 rs58667148 chr2:44481443 G/A cg00619915 chr2:44497795 NA -0.25 -5.7 -0.46 8.13e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs854765 0.964 rs72827413 chr17:17988299 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.65 -6.2 -0.49 7.84e-9 Total body bone mineral density; TGCT cis rs2721195 1.000 rs1871541 chr8:145681713 G/T cg11211951 chr8:145729740 GPT -0.21 -4.89 -0.4 3e-6 Age at first birth; TGCT cis rs10927875 0.632 rs904911 chr1:16126932 C/T cg21385522 chr1:16154831 NA -0.96 -15.62 -0.81 4.59e-31 Dilated cardiomyopathy; TGCT cis rs3924048 0.574 rs12410270 chr1:12612843 G/A cg00291366 chr1:12616550 NA 0.33 4.93 0.4 2.6e-6 Optic cup area; TGCT cis rs7192750 0.586 rs2335713 chr16:71904291 T/C cg06353428 chr16:71660113 MARVELD3 0.83 7.37 0.55 2.07e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs8180040 1.000 rs1638676 chr3:47327651 A/G cg27129171 chr3:47204927 SETD2 0.7 8.89 0.62 5.88e-15 Colorectal cancer; TGCT cis rs7258465 1.000 rs10403249 chr19:18604942 T/C cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs1008375 0.932 rs9291660 chr4:17663414 A/G cg16339924 chr4:17578868 LAP3 0.63 5.22 0.42 7.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3785574 0.962 rs2727324 chr17:61922102 G/C cg11494091 chr17:61959527 GH2 0.42 7.46 0.56 1.34e-11 Height; TGCT cis rs8179 0.761 rs42034 chr7:92239144 A/G cg15732164 chr7:92237376 CDK6 -0.3 -5.34 -0.43 4.37e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs7681440 0.904 rs6817001 chr4:90766019 C/T cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs769267 0.965 rs2269873 chr19:19392401 T/C cg03709012 chr19:19516395 GATAD2A 0.67 5.75 0.46 6.45e-8 Tonsillectomy; TGCT cis rs7017914 0.967 rs7814648 chr8:71603984 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs11030122 0.547 rs10767720 chr11:3953297 T/C cg18678763 chr11:4115507 RRM1 -0.39 -4.76 -0.39 5.24e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs2239547 0.522 rs2581779 chr3:53056199 T/C cg10802521 chr3:52805072 NEK4 0.6 5.38 0.44 3.52e-7 Schizophrenia; TGCT trans rs916888 0.821 rs199514 chr17:44856881 G/A cg22968622 chr17:43663579 NA -1.24 -11.14 -0.71 2.12e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7027203 0.576 rs7848045 chr9:96551824 G/A cg14598338 chr9:96623480 NA 0.5 7.25 0.55 3.86e-11 DNA methylation (variation); TGCT cis rs2486288 0.656 rs9920290 chr15:45548035 G/A cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs453301 0.597 rs7001187 chr8:8792782 G/A cg06636001 chr8:8085503 FLJ10661 -0.69 -5.92 -0.47 2.9e-8 Joint mobility (Beighton score); TGCT cis rs3820068 0.608 rs10927831 chr1:16028373 T/G cg05660106 chr1:15850417 CASP9 0.64 5.99 0.47 2.09e-8 Systolic blood pressure; TGCT cis rs950169 0.881 rs34591918 chr15:84950833 C/T cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs1577917 1.000 rs2812972 chr6:86669880 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg08280861 chr8:58055591 NA 0.49 5.38 0.43 3.64e-7 Developmental language disorder (linguistic errors); TGCT cis rs7914558 1.000 rs7094843 chr10:104806654 A/C cg15744005 chr10:104629667 AS3MT -0.38 -4.69 -0.39 7.04e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4891159 0.527 rs34956524 chr18:74130480 A/G cg24786174 chr18:74118243 ZNF516 0.67 13.58 0.77 2.65e-26 Longevity; TGCT cis rs4523957 0.620 rs9892754 chr17:2084565 G/T cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2239547 0.618 rs4687663 chr3:52870618 T/A cg10802521 chr3:52805072 NEK4 -0.63 -5.96 -0.47 2.41e-8 Schizophrenia; TGCT cis rs11190604 1.000 rs3793706 chr10:102269085 A/C cg23241863 chr10:102295624 HIF1AN -0.7 -5.38 -0.43 3.59e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs16867321 0.694 rs4666853 chr2:181439671 C/T cg23363182 chr2:181467187 NA 0.4 6.02 0.48 1.87e-8 Obesity; TGCT cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs7647973 1.000 rs3870341 chr3:49584745 A/G cg05785598 chr3:49045655 WDR6 0.38 4.76 0.39 5.38e-6 Menarche (age at onset); TGCT cis rs8077889 0.956 rs17742347 chr17:41846468 A/G cg26893861 chr17:41843967 DUSP3 -1.08 -13.44 -0.77 5.71e-26 Triglycerides; TGCT cis rs4081724 0.572 rs12151047 chr19:33810278 G/T cg18823272 chr19:34111733 CHST8 0.42 4.69 0.39 7.11e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28595532 0.920 rs114678295 chr4:119756281 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs6545883 0.862 rs1880866 chr2:61698972 G/C cg15711740 chr2:61764176 XPO1 -0.52 -4.69 -0.39 7.01e-6 Tuberculosis; TGCT cis rs2153535 0.580 rs1414350 chr6:8472331 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs2243480 0.901 rs73148097 chr7:65431787 A/C cg18252515 chr7:66147081 NA -1.22 -7.16 -0.54 6.34e-11 Diabetic kidney disease; TGCT cis rs5769765 0.862 rs9616386 chr22:50313179 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs4237845 0.816 rs61935769 chr12:58294344 G/A cg02175503 chr12:58329896 NA 0.52 4.77 0.39 5.09e-6 Intelligence (multi-trait analysis); TGCT cis rs611744 0.560 rs58605513 chr8:109279122 A/C cg21045802 chr8:109455806 TTC35 0.72 7.43 0.56 1.53e-11 Dupuytren's disease; TGCT cis rs4700695 0.614 rs394828 chr5:65209552 C/T cg21114390 chr5:65439923 SFRS12 0.67 4.69 0.39 7.07e-6 Facial morphology (factor 19); TGCT cis rs1218582 0.772 rs7528532 chr1:154874440 C/T cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs344364 0.511 rs1742469 chr16:1950244 C/T cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9303401 0.614 rs3803752 chr17:56540267 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.71 6.74 0.52 5.45e-10 Cognitive test performance; TGCT cis rs8062405 1.000 rs7187776 chr16:28857645 A/G cg09754948 chr16:28834200 ATXN2L 0.64 4.98 0.41 2.07e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7086627 0.515 rs7088877 chr10:82208860 C/G cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs950776 0.518 rs4243083 chr15:78833830 C/G cg06917634 chr15:78832804 PSMA4 -0.95 -9.52 -0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs7647973 0.593 rs1799844 chr3:49847642 G/A cg03034192 chr3:50606346 HEMK1;C3orf18 -0.37 -4.69 -0.39 7.03e-6 Menarche (age at onset); TGCT cis rs11578119 0.933 rs10800526 chr1:170480292 C/T cg09767346 chr1:170501363 GORAB -0.71 -5.64 -0.45 1.11e-7 Male-pattern baldness; TGCT cis rs7584330 0.652 rs7607231 chr2:238372896 T/C cg14458575 chr2:238380390 NA 0.48 7.57 0.56 7.54e-12 Prostate cancer; TGCT cis rs10504229 0.593 rs11781042 chr8:57993056 A/T cg08280861 chr8:58055591 NA 0.34 4.69 0.39 7.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs1372520 0.684 rs1442148 chr4:90748846 T/A cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs3617 0.539 rs11922975 chr3:52936763 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.52 5.06 0.41 1.48e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2282802 0.685 rs6889283 chr5:139653439 G/T cg01081189 chr5:139537190 NA 0.28 5.15 0.42 9.75e-7 Intelligence (multi-trait analysis); TGCT cis rs3125734 0.608 rs7905731 chr10:64018472 T/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.48 -0.37 1.67e-5 Rheumatoid arthritis; TGCT cis rs34638657 0.732 rs12597171 chr16:82200119 A/G cg09439754 chr16:82129088 HSD17B2 0.26 4.83 0.4 4.01e-6 Lung adenocarcinoma; TGCT cis rs6570726 0.791 rs12205752 chr6:145896118 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs921968 0.541 rs549026 chr2:219339283 T/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2120019 1.000 rs2083731 chr15:75368538 A/C cg17294928 chr15:75287854 SCAMP5 -0.85 -6.5 -0.5 1.78e-9 Blood trace element (Zn levels); TGCT cis rs11031096 0.711 rs10835694 chr11:4178757 G/C cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7267979 0.816 rs3746337 chr20:25208272 C/T cg14121845 chr20:25566513 NINL 0.49 5.02 0.41 1.75e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs7178572 0.568 rs7175674 chr15:77670910 C/T cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs6952808 0.594 rs3778965 chr7:2138296 G/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.44 -0.5 2.44e-9 Bipolar disorder and schizophrenia; TGCT cis rs9915657 0.870 rs12600458 chr17:70130545 C/T cg06234051 chr17:70120541 SOX9 -0.24 -4.82 -0.4 4.16e-6 Thyroid hormone levels; TGCT cis rs644799 0.965 rs10831430 chr11:95509638 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.46 0.6 6.27e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs79149102 0.579 rs12593476 chr15:75282092 A/C cg09165964 chr15:75287851 SCAMP5 -1.09 -6.08 -0.48 1.39e-8 Lung cancer; TGCT cis rs3020736 0.500 rs6002597 chr22:42488160 C/A cg15557168 chr22:42548783 NA 0.22 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs8017423 0.935 rs3742667 chr14:90767856 T/C cg04374321 chr14:90722782 PSMC1 -0.73 -6.71 -0.52 6.06e-10 Mortality in heart failure; TGCT cis rs936229 0.813 rs2301249 chr15:75092384 T/C cg10253484 chr15:75165896 SCAMP2 -0.64 -5.11 -0.42 1.16e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs875971 0.895 rs12698520 chr7:65918707 C/A cg11764359 chr7:65958608 NA 0.61 5.5 0.44 2.1e-7 Aortic root size; TGCT trans rs4332037 0.707 rs10268797 chr7:1873756 C/G cg25206134 chr2:45395956 NA -0.87 -6.98 -0.53 1.59e-10 Bipolar disorder; TGCT cis rs11731606 0.508 rs6827755 chr4:95309170 C/T cg00507259 chr4:95128692 SMARCAD1 0.63 4.67 0.39 7.66e-6 Mean platelet volume; TGCT cis rs2153535 0.580 rs2327050 chr6:8440630 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs1570884 0.516 rs7330830 chr13:50167929 T/A cg08779649 chr13:50194554 NA 0.38 6.1 0.48 1.25e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs245880 0.740 rs245889 chr7:29190626 C/T cg17163760 chr7:29186267 CPVL -0.42 -5.28 -0.43 5.71e-7 Warfarin maintenance dose; TGCT cis rs9341808 0.667 rs3805913 chr6:80927322 A/G cg08355045 chr6:80787529 NA 0.3 5.0 0.41 1.91e-6 Sitting height ratio; TGCT cis rs7945705 0.747 rs10840158 chr11:9020897 A/C cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -4.98 -0.41 2.11e-6 Hemoglobin concentration; TGCT cis rs11125080 1.000 rs11125079 chr2:46732215 C/T cg14327359 chr2:47419263 NA -0.41 -4.59 -0.38 1.07e-5 Anti-saccade response;Anti-saccade error rate in psychotic disorders; TGCT cis rs9993613 0.750 rs12643350 chr4:73535169 G/T cg15102770 chr4:73434591 ADAMTS3 0.51 4.46 0.37 1.83e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs4722166 0.630 rs12537614 chr7:22789551 C/G cg26061582 chr7:22766209 IL6 0.6 5.96 0.47 2.39e-8 Lung cancer; TGCT trans rs2727020 0.729 rs685789 chr11:49241228 G/A cg03929089 chr4:120376271 NA 0.71 7.69 0.57 3.98e-12 Coronary artery disease; TGCT cis rs17767294 0.708 rs72847361 chr6:27834216 G/T cg08851530 chr6:28072375 NA 1.58 7.16 0.54 6.15e-11 Parkinson's disease; TGCT cis rs116095464 0.558 rs10060089 chr5:205565 G/A cg22857025 chr5:266934 NA -0.34 -6.42 -0.5 2.63e-9 Breast cancer; TGCT cis rs3749237 0.595 rs35701831 chr3:49515000 A/C cg07636037 chr3:49044803 WDR6 0.63 5.98 0.47 2.26e-8 Resting heart rate; TGCT cis rs2243480 1.000 rs56291018 chr7:65390339 G/A cg20637647 chr7:64974828 NA 0.93 5.2 0.42 8.11e-7 Diabetic kidney disease; TGCT cis rs2067615 0.579 rs10778510 chr12:107162965 A/G cg15890332 chr12:107067104 RFX4 -0.29 -5.75 -0.46 6.56e-8 Heart rate; TGCT cis rs1784581 0.674 rs3016555 chr6:162391421 T/C cg17173639 chr6:162384350 PARK2 -0.46 -8.18 -0.59 2.92e-13 Itch intensity from mosquito bite; TGCT cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg09436375 chr6:42928200 GNMT -0.41 -5.18 -0.42 8.65e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4665809 0.590 rs7588328 chr2:26469788 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs11785400 0.793 rs11785376 chr8:143730412 C/T cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.79e-7 Schizophrenia; TGCT cis rs5769707 0.616 rs6009786 chr22:50015145 A/G cg05373962 chr22:49881684 NA -0.29 -4.97 -0.41 2.16e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9399135 1.000 rs4895435 chr6:135293463 C/A cg24558204 chr6:135376177 HBS1L 0.48 4.79 0.39 4.76e-6 Red blood cell count; TGCT cis rs9486719 1.000 rs34236778 chr6:96884556 C/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT trans rs16870629 0.541 rs2334955 chr5:1062444 A/G cg04701034 chr14:52536175 NID2 -0.74 -8.37 -0.6 1.01e-13 QT interval; TGCT cis rs711245 0.574 rs1179494 chr2:36809496 C/G cg15105969 chr2:36825350 FEZ2 -0.52 -4.52 -0.38 1.4e-5 Height; TGCT cis rs7424096 0.613 rs111805423 chr2:37248924 G/T cg14987922 chr2:37194071 STRN 0.52 4.65 0.39 8.4e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs6674176 0.597 rs9326136 chr1:44390392 A/G cg13606994 chr1:44402422 ARTN 0.51 5.5 0.44 2.07e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7949030 0.688 rs11231155 chr11:62365619 A/G cg22862634 chr11:62369728 EML3;MTA2 0.7 9.04 0.63 2.65e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2932538 0.922 rs12750621 chr1:113206502 G/C cg22162597 chr1:113214053 CAPZA1 0.28 5.98 0.47 2.2e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs6060960 0.502 rs15817 chr20:30193538 A/G cg13852791 chr20:30311386 BCL2L1 0.69 4.65 0.39 8.44e-6 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs9811920 0.809 rs1384062 chr3:99597928 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.44 -4.99 -0.41 1.97e-6 Axial length; TGCT cis rs9291683 0.546 rs7442336 chr4:10045783 G/A cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Bone mineral density; TGCT cis rs9467773 0.620 rs2130657 chr6:26650826 C/T cg05738196 chr6:26577821 NA 0.88 10.63 0.69 3.68e-19 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.595 rs3778982 chr7:2166233 T/C cg22963979 chr7:1858916 MAD1L1 -0.4 -6.38 -0.5 3.12e-9 Bipolar disorder and schizophrenia; TGCT cis rs9549367 0.713 rs9577211 chr13:113830718 G/C cg00898013 chr13:113819073 PROZ -0.57 -7.68 -0.57 4.14e-12 Platelet distribution width; TGCT cis rs5769707 0.967 rs9616327 chr22:50010891 G/A cg10356904 chr22:49881777 NA -0.23 -4.68 -0.39 7.53e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs17483521 chr4:98974058 A/T cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs4563143 0.675 rs56407818 chr19:29279379 G/A cg03161606 chr19:29218774 NA 0.62 6.0 0.47 2e-8 Methadone dose in opioid dependence; TGCT cis rs854765 0.547 rs2955356 chr17:17964717 G/A cg04398451 chr17:18023971 MYO15A 0.33 5.39 0.44 3.47e-7 Total body bone mineral density; TGCT cis rs9902453 0.780 rs10445384 chr17:28182685 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.59e-11 Coffee consumption (cups per day); TGCT cis rs3087591 0.919 rs11080148 chr17:29609922 T/C cg24425628 chr17:29625626 OMG;NF1 -0.43 -6.29 -0.49 4.94e-9 Hip circumference; TGCT cis rs74233809 0.892 rs11191447 chr10:104652323 C/T cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs13191362 1.000 rs67046187 chr6:163068532 C/A cg21926612 chr6:163149169 PACRG;PARK2 1.06 8.12 0.59 3.96e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs473651 0.935 rs472357 chr2:239355454 A/G cg21699342 chr2:239360505 ASB1 -0.17 -4.69 -0.39 7.05e-6 Multiple system atrophy; TGCT cis rs4237845 0.715 rs4760340 chr12:58275176 A/T cg03728296 chr12:58013271 SLC26A10 -0.4 -4.49 -0.37 1.58e-5 Intelligence (multi-trait analysis); TGCT cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg05738196 chr6:26577821 NA 0.88 11.4 0.72 5.07e-21 Intelligence (multi-trait analysis); TGCT cis rs6088590 1.000 rs2236270 chr20:33523155 G/T cg24642439 chr20:33292090 TP53INP2 0.67 5.52 0.44 1.92e-7 Coronary artery disease; TGCT cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs2288884 0.943 rs3752120 chr19:52552021 C/T cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs9534288 0.797 rs2182482 chr13:46582654 T/A cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs2299587 0.560 rs11987695 chr8:17781085 A/G cg01800426 chr8:17659068 MTUS1 -0.64 -5.52 -0.44 1.91e-7 Economic and political preferences; TGCT trans rs7613875 0.654 rs3774751 chr3:50209053 G/T cg21659725 chr3:3221576 CRBN -0.7 -7.99 -0.58 8.03e-13 Body mass index; TGCT cis rs7264396 0.570 rs1970576 chr20:34336720 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs4689388 0.890 rs4481292 chr4:6298375 C/T cg25554036 chr4:6271136 WFS1 0.56 7.87 0.58 1.48e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs78487399 0.808 rs6728106 chr2:43683885 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.45 -5.79 -0.46 5.47e-8 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7255045 0.702 rs2293682 chr19:12989560 G/A cg23899408 chr19:12877188 HOOK2 -0.62 -5.07 -0.41 1.39e-6 Mean corpuscular volume; TGCT cis rs7267979 0.966 rs2261795 chr20:25263136 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10479542 0.766 rs7733389 chr5:178974997 C/T cg14820908 chr5:178986412 RUFY1 0.46 4.82 0.4 4.1e-6 Lung cancer; TGCT cis rs137699 0.568 rs137682 chr22:39738425 A/C cg24399712 chr22:39784796 NA -0.72 -5.41 -0.44 3.16e-7 IgG glycosylation; TGCT cis rs2204008 0.712 rs12371182 chr12:38321143 A/C cg13010199 chr12:38710504 ALG10B 0.61 4.81 0.4 4.2e-6 Bladder cancer; TGCT cis rs1691799 0.867 rs1027400 chr12:66760922 A/T cg16791601 chr12:66731901 HELB -0.28 -6.03 -0.48 1.76e-8 White blood cell count (basophil); TGCT cis rs208520 0.526 rs6913344 chr6:66754285 A/C cg07460842 chr6:66804631 NA -1.03 -13.83 -0.78 6.68e-27 Exhaled nitric oxide output; TGCT cis rs868036 0.645 rs4776972 chr15:68083436 A/C cg27219399 chr15:67835830 MAP2K5 0.34 4.49 0.37 1.6e-5 Restless legs syndrome; TGCT cis rs7223966 0.921 rs2854207 chr17:61947107 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.51 0.38 1.5e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1865760 1.000 rs3799371 chr6:25912816 A/G cg16482183 chr6:26056742 HIST1H1C -0.53 -4.82 -0.4 4.09e-6 Height; TGCT trans rs877282 1.000 rs34257857 chr10:772993 C/A cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg19635926 chr16:89946313 TCF25 0.27 4.58 0.38 1.11e-5 Skin colour saturation; TGCT cis rs36051895 0.554 rs7856773 chr9:5204705 T/C cg02405213 chr9:5042618 JAK2 -0.75 -9.5 -0.65 2.05e-16 Pediatric autoimmune diseases; TGCT cis rs17767294 1.000 rs17767294 chr6:28054198 A/G cg08851530 chr6:28072375 NA 1.07 5.6 0.45 1.31e-7 Parkinson's disease; TGCT cis rs7178572 0.568 rs12900433 chr15:77495028 T/C cg15453836 chr15:77711506 NA -0.44 -4.91 -0.4 2.86e-6 Type 2 diabetes; TGCT cis rs6570726 0.935 rs379164 chr6:145829093 A/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1670533 1.000 rs6822863 chr4:1055606 G/A cg20887711 chr4:1340912 KIAA1530 0.69 5.48 0.44 2.32e-7 Recombination rate (females); TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg14820908 chr5:178986412 RUFY1 -0.59 -6.47 -0.5 2.08e-9 Lung cancer; TGCT cis rs682748 0.810 rs34630503 chr5:17139285 A/T cg23987134 chr5:17158319 LOC285696 -0.21 -5.19 -0.42 8.4e-7 Hippocampal atrophy; TGCT cis rs9910055 0.530 rs2269908 chr17:42294198 G/C cg13607699 chr17:42295918 UBTF 0.96 11.07 0.7 3.21e-20 Total body bone mineral density; TGCT cis rs12579753 0.797 rs1922561 chr12:82152640 C/A cg07988820 chr12:82153109 PPFIA2 -0.66 -7.01 -0.53 1.32e-10 Resting heart rate; TGCT cis rs12210905 0.688 rs12215289 chr6:27468705 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7267979 1.000 rs6115153 chr20:25325567 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.79 -8.24 -0.59 2.06e-13 Intelligence (multi-trait analysis); TGCT cis rs769267 0.965 rs6511026 chr19:19391402 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT trans rs7613875 0.620 rs13079006 chr3:49996924 G/T cg21659725 chr3:3221576 CRBN 0.67 7.53 0.56 9.05e-12 Body mass index; TGCT cis rs4900538 0.963 rs8017980 chr14:102961341 C/G cg18135206 chr14:102964638 TECPR2 0.22 5.19 0.42 8.24e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9372253 0.645 rs7753212 chr6:110700229 T/C cg19196401 chr6:110721138 DDO -0.42 -5.75 -0.46 6.45e-8 Platelet distribution width; TGCT cis rs854765 0.583 rs7503334 chr17:17779458 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.5 -0.44 2.04e-7 Total body bone mineral density; TGCT trans rs7726839 0.561 rs4957049 chr5:579080 C/A cg11887960 chr12:57824829 NA 0.96 8.01 0.58 7.22e-13 Obesity-related traits; TGCT cis rs3784262 0.669 rs3784257 chr15:58262974 C/T cg12031962 chr15:58353849 ALDH1A2 0.42 6.16 0.48 9.41e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs931812 0.757 rs13251801 chr8:101902629 A/T cg20993868 chr7:22813445 NA 0.32 6.63 0.51 9.13e-10 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs12477438 0.501 rs12619780 chr2:99707307 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.1 16.08 0.82 4.04e-32 Chronic sinus infection; TGCT cis rs2180341 1.000 rs2144742 chr6:127595786 C/A cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs4769475 1.000 rs7320397 chr13:26730629 G/A cg19000612 chr13:26506281 ATP8A2 0.34 4.66 0.39 8.12e-6 Response to Homoharringtonine (cytotoxicity); TGCT cis rs2019216 0.500 rs908696 chr17:21940987 T/G cg22648282 chr17:21454238 C17orf51 -0.58 -4.95 -0.41 2.37e-6 Pelvic organ prolapse; TGCT cis rs2658782 0.547 rs3133454 chr11:93059019 A/C cg15737290 chr11:93063684 CCDC67 1.05 11.65 0.72 1.24e-21 Pulmonary function decline; TGCT cis rs61884328 0.789 rs61897788 chr11:47181051 A/T cg13308137 chr11:47528955 CUGBP1 0.38 4.44 0.37 1.94e-5 Total body bone mineral density (age over 60); TGCT cis rs453301 0.658 rs3855900 chr8:8901921 A/G cg15556689 chr8:8085844 FLJ10661 -0.66 -5.39 -0.44 3.47e-7 Joint mobility (Beighton score); TGCT cis rs231513 0.954 rs231510 chr17:41966470 T/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.21 -0.42 7.57e-7 Cognitive function; TGCT cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg10207240 chr12:122356781 WDR66 0.34 4.66 0.39 8.03e-6 Mean corpuscular volume; TGCT cis rs586688 0.556 rs1256473 chr1:201652342 T/G cg07139329 chr1:201708558 NAV1 -0.51 -5.29 -0.43 5.27e-7 Obesity-related traits; TGCT cis rs9400467 0.537 rs12211045 chr6:111498116 C/T cg15721981 chr6:111408429 SLC16A10 0.78 4.7 0.39 6.66e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs57221529 0.766 rs72703075 chr5:592819 C/T cg09021430 chr5:549028 NA -0.42 -5.55 -0.45 1.64e-7 Lung disease severity in cystic fibrosis; TGCT cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg03735888 chr19:58951602 ZNF132 0.55 4.83 0.4 3.98e-6 Uric acid clearance; TGCT cis rs4654899 0.758 rs6690574 chr1:21504279 G/A cg01072550 chr1:21505969 NA -0.58 -9.63 -0.65 9.9900000000000006e-17 Superior frontal gyrus grey matter volume; TGCT cis rs11112613 0.653 rs59504344 chr12:105950837 C/T cg03607813 chr12:105948248 NA 0.51 6.11 0.48 1.19e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs11614913 0.509 rs12300425 chr12:54395082 G/T cg05643303 chr12:54402714 HOXC8 -0.72 -6.15 -0.48 9.66e-9 Waist circumference adjusted for body mass index; TGCT cis rs7104764 0.957 rs56357554 chr11:204715 C/T cg18336825 chr11:236787 PSMD13;SIRT3 -1.02 -10.55 -0.69 5.9e-19 Menarche (age at onset); TGCT cis rs9611565 0.512 rs45500192 chr22:42177899 A/G cg06481639 chr22:41940642 POLR3H -0.66 -5.75 -0.46 6.46e-8 Vitiligo; TGCT cis rs11085466 1.000 rs4399664 chr19:21778026 C/T cg23026602 chr19:21646605 NA -0.53 -4.55 -0.38 1.28e-5 Colorectal or endometrial cancer; TGCT cis rs2046867 0.908 rs62251601 chr3:72786768 C/G cg25664220 chr3:72788482 NA -0.56 -7.03 -0.53 1.25e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1218582 0.772 rs4240874 chr1:154885779 C/T cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs7267979 0.966 rs2387882 chr20:25378802 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4332037 0.539 rs11762636 chr7:2061111 C/A cg25834613 chr7:1915315 MAD1L1 -0.51 -4.99 -0.41 1.95e-6 Bipolar disorder; TGCT cis rs763121 0.853 rs138705 chr22:39133803 C/T cg06022373 chr22:39101656 GTPBP1 0.8 7.56 0.56 7.77e-12 Menopause (age at onset); TGCT cis rs7940866 0.834 rs10894298 chr11:130840571 C/A cg05962950 chr11:130786565 SNX19 0.73 7.14 0.54 6.99e-11 Schizophrenia; TGCT cis rs9674544 0.556 rs1390154 chr17:47071483 A/G cg20966754 chr17:47091339 IGF2BP1 -0.43 -4.71 -0.39 6.46e-6 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs2463822 0.583 rs72917377 chr11:62025930 A/G cg06239285 chr11:62104954 ASRGL1 -0.96 -6.16 -0.48 9.22e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs57143961 1 rs57143961 chr19:16533225 C/CT cg14704714 chr19:15740395 CYP4F8 -0.32 -4.44 -0.37 1.97e-5 Lymphocyte percentage of white cells; TGCT cis rs10540 0.730 rs34690033 chr11:492677 G/C cg03934478 chr11:495069 RNH1 0.36 5.84 0.46 4.21e-8 Body mass index; TGCT cis rs2153535 0.580 rs6597335 chr6:8527714 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9457247 1.000 rs10946199 chr6:167404492 G/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs11785400 0.793 rs4736367 chr8:143742477 G/A cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs7617773 0.780 rs35297395 chr3:48342882 C/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs892961 0.932 rs7216909 chr17:75405234 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.48 0.5 1.92e-9 Airflow obstruction; TGCT cis rs9362426 0.708 rs7744793 chr6:88102040 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.44 4.81 0.4 4.29e-6 Depressive episodes in bipolar disorder; TGCT cis rs7937682 0.889 rs1940529 chr11:111498523 G/C cg09085632 chr11:111637200 PPP2R1B -1.1 -11.28 -0.71 9.81e-21 Primary sclerosing cholangitis; TGCT cis rs7681440 0.874 rs1442154 chr4:90775761 C/G cg20003494 chr4:90757398 SNCA -0.56 -5.35 -0.43 4.11e-7 Dementia with Lewy bodies; TGCT cis rs1719271 1.000 rs1719271 chr15:65183801 C/T cg26157579 chr15:65137040 PLEKHO2 0.35 4.59 0.38 1.09e-5 Platelet count; TGCT cis rs2235642 0.750 rs2859310 chr16:1656765 C/T cg00463982 chr16:1583984 IFT140;TMEM204 0.27 4.53 0.38 1.37e-5 Coronary artery disease; TGCT cis rs2070488 0.775 rs2051213 chr3:38560254 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.7 6.64 0.51 8.65e-10 Electrocardiographic conduction measures; TGCT cis rs10197940 0.624 rs10497081 chr2:152353395 T/G cg19508488 chr2:152266495 RIF1 0.72 6.55 0.51 1.38e-9 Lung cancer; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs67073037 0.868 rs4666142 chr2:29171544 A/G cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs854765 0.647 rs854791 chr17:18029857 C/T cg04398451 chr17:18023971 MYO15A -0.38 -6.45 -0.5 2.26e-9 Total body bone mineral density; TGCT cis rs67311347 0.955 rs12487955 chr3:40412853 T/C cg13683864 chr3:40499215 RPL14 -1.12 -11.9 -0.73 2.94e-22 Renal cell carcinoma; TGCT cis rs9611565 0.568 rs2413656 chr22:42129357 G/T cg13695892 chr22:41940480 POLR3H 0.83 7.96 0.58 9.24e-13 Vitiligo; TGCT cis rs1797081 0.967 rs780633 chr10:16863161 C/T cg14835575 chr10:16859367 RSU1 0.44 5.31 0.43 4.92e-7 Platelet distribution width; TGCT cis rs2282802 0.685 rs2337082 chr5:139649201 G/A cg01081189 chr5:139537190 NA 0.28 5.15 0.42 9.75e-7 Intelligence (multi-trait analysis); TGCT cis rs4076764 0.801 rs4571944 chr1:163367975 T/C cg24596788 chr1:163392923 NA -0.17 -5.19 -0.42 8.2e-7 Motion sickness; TGCT cis rs3806843 0.576 rs246027 chr5:140333601 A/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs1046896 0.538 rs3803771 chr17:80687758 G/A cg00960700 chr17:80709150 TBCD -0.49 -4.99 -0.41 1.97e-6 Glycated hemoglobin levels; TGCT cis rs6964587 1.000 rs4727267 chr7:91570290 G/C cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs7824557 0.547 rs2572370 chr8:11238587 A/G cg21775007 chr8:11205619 TDH -0.75 -7.08 -0.54 9.52e-11 Retinal vascular caliber; TGCT cis rs7809950 1.000 rs4727684 chr7:107226470 C/T cg23024343 chr7:107201750 COG5 -0.33 -5.13 -0.42 1.09e-6 Coronary artery disease; TGCT cis rs2688608 0.868 rs2688625 chr10:75631548 T/C cg04320760 chr10:75533139 FUT11 -0.32 -4.93 -0.4 2.61e-6 Inflammatory bowel disease; TGCT cis rs4713118 0.662 rs9380046 chr6:28030499 T/C cg12963246 chr6:28129442 ZNF389 0.45 4.51 0.38 1.48e-5 Parkinson's disease; TGCT cis rs9467773 0.566 rs66972160 chr6:26359306 T/C cg05738196 chr6:26577821 NA -0.63 -6.8 -0.52 3.97e-10 Intelligence (multi-trait analysis); TGCT cis rs4076943 0.634 rs7111708 chr11:11270284 A/T cg21653586 chr11:10530636 NA 0.49 4.97 0.41 2.14e-6 Post bronchodilator FEV1; TGCT cis rs9807989 0.507 rs10203558 chr2:103027640 T/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs137699 0.695 rs137653 chr22:39732171 A/G cg11247378 chr22:39784982 NA 0.46 5.0 0.41 1.92e-6 IgG glycosylation; TGCT cis rs7786808 0.530 rs7785656 chr7:158184164 C/G cg01191920 chr7:158217561 PTPRN2 -0.35 -4.92 -0.4 2.64e-6 Obesity-related traits; TGCT cis rs6964587 0.967 rs4729015 chr7:91561592 T/G cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs13256369 0.901 rs13251887 chr8:8568678 G/A cg17143192 chr8:8559678 CLDN23 0.58 5.56 0.45 1.56e-7 Obesity-related traits; TGCT cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 1.1 6.25 0.49 6.06e-9 Alzheimer's disease; TGCT cis rs3785574 0.962 rs2665835 chr17:61903258 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.57 4.91 0.4 2.83e-6 Height; TGCT cis rs72717009 0.825 rs7552317 chr1:161479438 C/T cg23840854 chr1:161414152 NA -0.97 -5.92 -0.47 2.93e-8 Rheumatoid arthritis; TGCT cis rs4722166 0.630 rs12700390 chr7:22777129 G/T cg26061582 chr7:22766209 IL6 0.57 7.36 0.55 2.27e-11 Lung cancer; TGCT cis rs12188164 1.000 rs72717414 chr5:429818 C/G cg26850624 chr5:429559 AHRR -0.2 -4.81 -0.4 4.22e-6 Cystic fibrosis severity; TGCT cis rs3087591 0.919 rs12603838 chr17:29408059 C/T cg24425628 chr17:29625626 OMG;NF1 0.47 7.31 0.55 2.94e-11 Hip circumference; TGCT cis rs3733585 0.736 rs4543113 chr4:10008305 G/A cg00071950 chr4:10020882 SLC2A9 0.62 7.05 0.53 1.12e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs453301 0.568 rs13281377 chr8:8811564 C/T cg06636001 chr8:8085503 FLJ10661 0.74 5.99 0.47 2.1e-8 Joint mobility (Beighton score); TGCT cis rs9611565 0.921 rs2143695 chr22:41728620 A/G cg06634786 chr22:41940651 POLR3H -0.59 -5.59 -0.45 1.36e-7 Vitiligo; TGCT cis rs1577917 1.000 rs12192992 chr6:86609915 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs17718580 0.536 rs59807161 chr14:51091475 G/C cg04730355 chr14:51134070 SAV1 1.24 8.74 0.62 1.38e-14 Cognitive performance; TGCT cis rs1692580 0.777 rs10910037 chr1:2184280 T/C cg21194808 chr1:2205498 SKI 0.29 5.5 0.44 2.06e-7 Coronary artery disease; TGCT trans rs2749592 0.531 rs994804 chr10:37900140 A/C cg17830980 chr10:43048298 ZNF37B 0.65 6.85 0.52 3.1e-10 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs597539 0.616 rs10896386 chr11:68722694 C/T cg21963583 chr11:68658836 MRPL21 0.36 6.09 0.48 1.3e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10883723 0.810 rs3781289 chr10:104244991 G/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9341808 0.754 rs6918172 chr6:81019242 A/G cg08355045 chr6:80787529 NA 0.27 4.61 0.38 9.8200000000000008e-06 Sitting height ratio; TGCT cis rs9611565 0.625 rs2076199 chr22:41903743 G/T cg06481639 chr22:41940642 POLR3H -0.55 -4.77 -0.39 5.11e-6 Vitiligo; TGCT cis rs1862618 0.853 rs33326 chr5:56142601 G/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs9362426 1.000 rs406900 chr6:88085447 T/C cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.19 0.42 8.5e-7 Depressive episodes in bipolar disorder; TGCT cis rs79349575 0.651 rs4378658 chr17:46993370 G/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs11105298 0.891 rs10858906 chr12:89934474 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.85 -0.4 3.63e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7937682 0.575 rs11604704 chr11:111764396 G/A cg09085632 chr11:111637200 PPP2R1B 0.91 8.56 0.61 3.6e-14 Primary sclerosing cholangitis; TGCT trans rs6089829 0.925 rs6062396 chr20:61667949 T/C cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs56235845 0.694 rs12055081 chr5:176757191 C/T cg16006841 chr5:176797999 RGS14 0.5 7.45 0.56 1.38e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs4295623 0.559 rs4841600 chr8:11688148 T/C cg02840367 chr8:11660030 FDFT1 -0.66 -5.38 -0.43 3.63e-7 Morning vs. evening chronotype; TGCT cis rs4746818 1.000 rs7899844 chr10:70949694 A/G cg11621586 chr10:70884670 VPS26A 1.21 10.5 0.69 7.7e-19 Left atrial antero-posterior diameter; TGCT cis rs7760949 0.852 rs9464423 chr6:13931851 A/G cg27413430 chr6:13925136 RNF182 0.74 6.83 0.52 3.37e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs57590327 0.503 rs13066091 chr3:81589912 T/C cg07356753 chr3:81810745 GBE1 -0.61 -5.1 -0.42 1.24e-6 Extraversion; TGCT cis rs10504229 0.635 rs72649130 chr8:58053810 G/T cg02725872 chr8:58115012 NA -0.39 -4.74 -0.39 5.67e-6 Developmental language disorder (linguistic errors); TGCT cis rs62388641 0.539 rs56304710 chr6:1542576 C/T cg01806741 chr6:1527072 NA -0.3 -4.63 -0.38 9.19e-6 Daytime sleep phenotypes; TGCT cis rs74705753 1.000 rs74705753 chr22:42201517 A/G cg03806693 chr22:41940476 POLR3H -1.04 -5.02 -0.41 1.72e-6 Intelligence (multi-trait analysis); TGCT cis rs1395 1.000 rs2014252 chr2:27462405 T/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.76 0.52 4.84e-10 Blood metabolite levels; TGCT cis rs986417 0.551 rs1956553 chr14:60952298 T/A cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs992157 0.710 rs7569907 chr2:219070551 C/T cg00012203 chr2:219082015 ARPC2 0.81 10.19 0.68 4.34e-18 Colorectal cancer; TGCT trans rs57221529 0.709 rs72706611 chr5:561146 C/A cg11887960 chr12:57824829 NA 1.16 9.59 0.65 1.25e-16 Lung disease severity in cystic fibrosis; TGCT cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6088580 0.634 rs6059850 chr20:33044784 C/G cg08999081 chr20:33150536 PIGU 0.29 5.59 0.45 1.37e-7 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs4252435 0.520 rs7797896 chr7:142641189 T/C cg09833174 chr7:143059591 FAM131B -1.02 -4.65 -0.39 8.26e-6 Cancer; TGCT cis rs3806843 0.576 rs251376 chr5:140253689 A/G cg07102913 chr5:140593443 PCDHB13 0.48 4.59 0.38 1.06e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs4851266 1.000 rs893246 chr2:100814917 T/C cg22139774 chr2:100720529 AFF3 -0.36 -5.38 -0.44 3.55e-7 Educational attainment; TGCT cis rs9325144 0.647 rs1875609 chr12:39018259 C/T cg13010199 chr12:38710504 ALG10B -0.51 -4.58 -0.38 1.13e-5 Morning vs. evening chronotype; TGCT cis rs7264396 0.790 rs6060542 chr20:34249061 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs17376456 0.866 rs13356088 chr5:93423479 C/T cg25358565 chr5:93447407 FAM172A 0.87 6.63 0.51 9.2e-10 Diabetic retinopathy; TGCT cis rs11190604 1.000 rs10883512 chr10:102308516 A/G cg23241863 chr10:102295624 HIF1AN 0.68 5.13 0.42 1.08e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs57920188 0.568 rs10915665 chr1:4093717 G/T cg20703997 chr1:4087676 NA 0.47 5.03 0.41 1.71e-6 Interleukin-17 levels; TGCT cis rs2243480 1.000 rs958550 chr7:65635679 C/T cg20637647 chr7:64974828 NA -0.9 -5.21 -0.42 7.51e-7 Diabetic kidney disease; TGCT trans rs4650994 1.000 rs4077194 chr1:178533832 A/C cg05059571 chr16:84539110 KIAA1609 0.38 7.17 0.54 5.97e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9372498 0.536 rs13437605 chr6:118899014 C/T cg21191810 chr6:118973309 C6orf204 -0.39 -5.04 -0.41 1.59e-6 Diastolic blood pressure; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg27535305 chr1:53392650 SCP2 -0.24 -4.9 -0.4 2.94e-6 Monocyte count; TGCT cis rs5769707 0.681 rs4824068 chr22:50024801 G/A cg06623630 chr22:50017776 C22orf34 -0.27 -4.7 -0.39 6.81e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs11249608 0.548 rs34054398 chr5:178458371 A/G cg23951258 chr5:178450506 ZNF879 0.44 4.56 0.38 1.22e-5 Pubertal anthropometrics; TGCT cis rs9341808 0.718 rs3812121 chr6:80968727 A/G cg08355045 chr6:80787529 NA 0.29 4.95 0.41 2.37e-6 Sitting height ratio; TGCT cis rs208520 0.690 rs864314 chr6:66814830 G/A cg07460842 chr6:66804631 NA -1.07 -15.41 -0.81 1.34e-30 Exhaled nitric oxide output; TGCT cis rs12477438 0.501 rs6727749 chr2:99793590 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs910316 0.763 rs175014 chr14:75456927 A/G cg08847533 chr14:75593920 NEK9 -0.86 -9.08 -0.63 2.05e-15 Height; TGCT cis rs7091068 0.550 rs7901909 chr10:95492508 C/T cg20715218 chr10:95462985 C10orf4 0.5 5.7 0.46 8.21e-8 Urinary tract infection frequency; TGCT trans rs6952808 0.582 rs11763870 chr7:2027448 T/C cg24694675 chr1:76082066 NA -0.64 -6.63 -0.51 9.42e-10 Bipolar disorder and schizophrenia; TGCT cis rs539096 0.872 rs3828150 chr1:44050856 T/C cg12908607 chr1:44402522 ARTN -0.48 -4.83 -0.4 3.93e-6 Intelligence (multi-trait analysis); TGCT cis rs9443645 0.901 rs9448580 chr6:79551812 C/G cg09184832 chr6:79620586 NA -0.47 -5.23 -0.43 6.98e-7 Intelligence (multi-trait analysis); TGCT trans rs797680 0.856 rs2765545 chr1:93677269 G/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.88 -0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs832540 0.864 rs832576 chr5:56163255 C/A cg12311346 chr5:56204834 C5orf35 -0.49 -5.37 -0.43 3.73e-7 Coronary artery disease; TGCT cis rs9467711 0.606 rs9358937 chr6:26374274 C/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs829418 0.582 rs747662 chr1:21947218 C/G cg07081061 chr6:3350901 SLC22A23 -0.71 -6.88 -0.53 2.6e-10 Neurocognitive impairment in HIV-1 infection (continuous); TGCT cis rs1205863 1.000 rs960414 chr6:11946676 G/A cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs763014 0.833 rs916415 chr16:632115 G/A cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs9611565 0.512 rs139560 chr22:42194962 A/G cg06481639 chr22:41940642 POLR3H -0.67 -5.95 -0.47 2.57e-8 Vitiligo; TGCT cis rs868036 0.681 rs9920643 chr15:68104314 C/T cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs2836974 0.568 rs442972 chr21:40534757 C/T cg11644478 chr21:40555479 PSMG1 -0.61 -5.72 -0.46 7.44e-8 Cognitive function; TGCT cis rs6121246 0.609 rs1009453 chr20:30404840 C/G cg10886678 chr20:30946050 ASXL1 -0.57 -4.79 -0.4 4.68e-6 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.683 rs59679713 chr8:58134370 G/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs12142240 0.698 rs17361812 chr1:46814008 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs9467773 1.000 rs6910899 chr6:26524339 A/G cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs4918072 0.728 rs7099351 chr10:105710933 A/G cg11005552 chr10:105648138 OBFC1 0.34 4.47 0.37 1.75e-5 Coronary artery disease; TGCT cis rs57590327 0.503 rs1464790 chr3:81852923 A/T cg07356753 chr3:81810745 GBE1 0.67 6.15 0.48 9.91e-9 Extraversion; TGCT cis rs797680 0.754 rs3767964 chr1:93815490 T/C cg17826107 chr1:92977322 EVI5 -0.24 -5.65 -0.45 1.05e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs4642101 0.561 rs4560285 chr3:12809066 G/A cg05775895 chr3:12838266 CAND2 0.49 4.75 0.39 5.58e-6 QRS complex (12-leadsum); TGCT cis rs319204 0.843 rs319161 chr5:146300154 T/C cg25021259 chr5:146258546 PPP2R2B 0.37 4.59 0.38 1.06e-5 Schizophrenia; TGCT cis rs7809950 1.000 rs4727681 chr7:107096144 T/C cg23024343 chr7:107201750 COG5 -0.33 -5.27 -0.43 5.81e-7 Coronary artery disease; TGCT cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg09467607 chr2:36825704 FEZ2 0.33 4.67 0.39 7.72e-6 Height; TGCT cis rs6570726 0.905 rs406799 chr6:145821837 G/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs17767294 0.615 rs72845058 chr6:27647420 T/C cg08851530 chr6:28072375 NA 1.56 7.38 0.55 1.95e-11 Parkinson's disease; TGCT cis rs73001065 0.636 rs11668104 chr19:19426181 G/A cg03709012 chr19:19516395 GATAD2A 0.87 4.66 0.39 8.18e-6 LDL cholesterol; TGCT cis rs727505 1.000 rs10233596 chr7:124556659 A/G cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.63e-5 Lewy body disease; TGCT trans rs7726839 0.718 rs6887972 chr5:597274 C/G cg11887960 chr12:57824829 NA 0.95 7.37 0.55 2.12e-11 Obesity-related traits; TGCT cis rs6988636 0.710 rs62521806 chr8:124161054 C/T cg27053337 chr8:124217698 FAM83A 0.71 5.42 0.44 3e-7 Urinary uromodulin levels; TGCT cis rs11031096 0.502 rs4910598 chr11:4101368 C/T cg18678763 chr11:4115507 RRM1 -0.45 -5.42 -0.44 2.96e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs981844 0.712 rs62325150 chr4:154728117 T/G cg14289246 chr4:154710475 SFRP2 1.04 9.67 0.66 8.17e-17 Response to statins (LDL cholesterol change); TGCT trans rs7824557 0.564 rs2437152 chr8:11235497 G/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.48e-10 Retinal vascular caliber; TGCT cis rs61867294 0.597 rs6584641 chr10:106691096 C/T cg08000847 chr10:105880925 C10orf78 -0.49 -4.46 -0.37 1.8e-5 Schizophrenia; TGCT cis rs6748734 0.817 rs10182575 chr2:241806690 C/T cg07537917 chr2:241836409 C2orf54 -0.2 -4.47 -0.37 1.71e-5 Urinary metabolites; TGCT cis rs225245 0.817 rs225269 chr17:33967931 G/T cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.53e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs1733410 0.504 rs11181874 chr12:37912890 C/A cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs2180341 0.920 rs9398836 chr6:127576497 T/G cg24812749 chr6:127587940 RNF146 0.93 7.35 0.55 2.36e-11 Breast cancer; TGCT cis rs6754311 0.773 rs632632 chr2:136638216 A/G cg07169764 chr2:136633963 MCM6 0.6 5.71 0.46 7.98e-8 Mosquito bite size; TGCT cis rs12048904 0.619 rs10783153 chr1:101328230 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.85 8.05 0.59 5.63e-13 Multiple sclerosis; TGCT cis rs7666738 0.830 rs11727653 chr4:99001774 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs13256369 0.802 rs11249885 chr8:8562008 C/T cg18904891 chr8:8559673 CLDN23 0.59 5.54 0.45 1.75e-7 Obesity-related traits; TGCT cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg12310025 chr6:25882481 NA -0.62 -6.53 -0.51 1.53e-9 Blood metabolite levels; TGCT cis rs2224391 0.590 rs2753235 chr6:5252182 C/T cg09085698 chr6:5261316 LYRM4;FARS2 1.01 6.92 0.53 2.18e-10 Height; TGCT cis rs12136530 0.593 rs9287047 chr1:19736534 T/C cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs9368481 0.761 rs9348746 chr6:26970357 C/G cg10547057 chr6:26987810 LOC100270746;C6orf41 -0.47 -4.88 -0.4 3.15e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2032447 0.702 rs199753 chr6:26001888 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.92 10.02 0.67 1.16e-17 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.568 rs428602 chr21:40547004 A/G cg11890956 chr21:40555474 PSMG1 0.8 7.66 0.57 4.53e-12 Cognitive function; TGCT cis rs10858047 0.883 rs222493 chr1:115128087 A/G cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs34014631 0.892 rs79550344 chr10:103613098 G/A cg22630918 chr10:102748988 C10orf2 0.43 4.8 0.4 4.57e-6 Coronary artery calcification; TGCT cis rs912057 0.833 rs1294421 chr6:6743149 A/C cg06612196 chr6:6737390 NA 0.37 4.88 0.4 3.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9928842 0.765 rs6564222 chr16:75225044 A/G cg09066997 chr16:75300724 BCAR1 0.28 5.14 0.42 1.06e-6 Alcoholic chronic pancreatitis; TGCT trans rs4332037 0.707 rs62435130 chr7:1890002 C/T cg25206134 chr2:45395956 NA 0.96 8.2 0.59 2.59e-13 Bipolar disorder; TGCT cis rs586688 1.000 rs586688 chr1:201630955 G/A cg05779441 chr1:201574716 NA 0.29 4.7 0.39 6.78e-6 Obesity-related traits; TGCT trans rs7819412 0.668 rs2409715 chr8:11010136 A/T cg15556689 chr8:8085844 FLJ10661 -0.81 -7.28 -0.55 3.44e-11 Triglycerides; TGCT cis rs4918072 0.754 rs4918065 chr10:105617578 T/C cg11005552 chr10:105648138 OBFC1 0.4 5.15 0.42 9.8e-7 Coronary artery disease; TGCT cis rs736408 0.581 rs3617 chr3:52833805 C/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.66 -0.39 8.06e-6 Bipolar disorder; TGCT cis rs611744 0.870 rs633794 chr8:109174702 A/G cg21045802 chr8:109455806 TTC35 0.68 6.08 0.48 1.4e-8 Dupuytren's disease; TGCT cis rs9916302 0.904 rs1966916 chr17:37425238 T/G cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs1153858 1.000 rs1346268 chr15:45673029 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2274273 0.745 rs8005399 chr14:55542845 A/G cg01923255 chr14:55878535 KIAA0831 0.56 4.59 0.38 1.09e-5 Protein biomarker; TGCT trans rs1814175 0.817 rs4881658 chr11:49941123 G/A cg03929089 chr4:120376271 NA -0.7 -7.87 -0.58 1.51e-12 Height; TGCT cis rs10791097 0.967 rs10750450 chr11:130719061 G/T cg12179176 chr11:130786555 SNX19 0.65 6.88 0.53 2.63e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11122272 0.701 rs2486725 chr1:231540288 G/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs57920188 0.585 rs12127463 chr1:4079127 C/T cg20703997 chr1:4087676 NA 0.46 5.71 0.46 8.05e-8 Interleukin-17 levels; TGCT cis rs4727027 0.868 rs10952799 chr7:148840772 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.55 0.38 1.25e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6918586 0.616 rs1056314 chr6:26114653 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.7 6.6 0.51 1.09e-9 Schizophrenia; TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs7843479 0.601 rs9969551 chr8:21860007 T/C cg17168535 chr8:21777572 XPO7 0.8 7.93 0.58 1.11e-12 Mean corpuscular volume; TGCT trans rs1005277 0.602 rs1780141 chr10:38504299 T/C cg17830980 chr10:43048298 ZNF37B -0.81 -10.13 -0.67 6.19e-18 Extrinsic epigenetic age acceleration; TGCT cis rs7296418 0.885 rs1051434 chr12:123641200 C/T cg05973401 chr12:123451056 ABCB9 0.54 4.47 0.37 1.71e-5 Platelet count; TGCT cis rs2033711 0.870 rs4801583 chr19:58918405 A/G cg13877915 chr19:58951672 ZNF132 0.87 10.88 0.7 9.34e-20 Uric acid clearance; TGCT cis rs929354 0.772 rs3802125 chr7:156970563 A/C cg05182265 chr7:156933206 UBE3C -0.37 -8.21 -0.59 2.42e-13 Body mass index; TGCT cis rs911555 0.504 rs61995761 chr14:104075712 T/C cg26031613 chr14:104095156 KLC1 0.61 5.6 0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs17401966 0.867 rs61775872 chr1:10279308 T/C cg19773385 chr1:10388646 KIF1B -0.22 -4.65 -0.39 8.41e-6 Hepatocellular carcinoma; TGCT cis rs7267979 1.000 rs7019 chr20:25278278 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs58696666 chr4:99006913 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs7662948 chr4:99020132 G/C cg05340658 chr4:99064831 C4orf37 0.46 5.13 0.42 1.09e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs68170813 0.562 rs17429825 chr7:107050731 C/T cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs12497850 1.000 rs6788650 chr3:48749543 T/C cg06212747 chr3:49208901 KLHDC8B 0.62 5.94 0.47 2.65e-8 Parkinson's disease; TGCT cis rs4665809 0.590 rs13387855 chr2:26420708 T/G cg22920501 chr2:26401640 FAM59B -0.78 -6.26 -0.49 5.88e-9 Gut microbiome composition (summer); TGCT cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.63 5.12 0.42 1.11e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3806843 0.548 rs246055 chr5:140325662 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7098414 0.531 rs4120852 chr10:82018594 G/T cg01528321 chr10:82214614 TSPAN14 0.63 5.67 0.45 9.43e-8 Post bronchodilator FEV1; TGCT cis rs9910055 0.573 rs228768 chr17:42191893 A/C cg19774624 chr17:42201019 HDAC5 -0.64 -6.85 -0.52 3.1e-10 Total body bone mineral density; TGCT cis rs5769765 1.000 rs4824106 chr22:50267822 T/C cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7772486 0.686 rs702314 chr6:146003510 G/A cg05347473 chr6:146136440 FBXO30 -0.48 -4.51 -0.38 1.47e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9534288 0.699 rs1467665 chr13:46662919 C/T cg15192986 chr13:46630673 CPB2 -0.51 -6.02 -0.48 1.87e-8 Blood protein levels; TGCT cis rs11209002 0.614 rs12140736 chr1:67586671 T/C cg02640540 chr1:67518911 SLC35D1 0.56 4.62 0.38 9.4e-6 Crohn's disease; TGCT cis rs2346177 1.000 rs12619985 chr2:46641627 T/C cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.64 -0.38 8.81e-6 HDL cholesterol; TGCT cis rs5769765 0.954 rs5770707 chr22:50244533 G/A cg15316289 chr22:50310904 ALG12;CRELD2 -0.37 -5.7 -0.46 8.42e-8 Schizophrenia; TGCT cis rs4720575 1.000 rs917108 chr7:47088047 A/G cg00036614 chr7:47093842 NA -0.21 -5.14 -0.42 1.02e-6 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs7681440 0.874 rs10028246 chr4:90766704 G/A cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs709400 0.628 rs1951392 chr14:103853367 T/G cg12935359 chr14:103987150 CKB -0.38 -5.59 -0.45 1.35e-7 Body mass index; TGCT cis rs11874712 1.000 rs1800640 chr18:43671400 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.51 4.84 0.4 3.81e-6 Migraine - clinic-based; TGCT cis rs10876993 0.749 rs703832 chr12:58024626 G/C cg15848620 chr12:58087721 OS9 -0.76 -5.73 -0.46 7.12e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs10838634 1.000 rs7123729 chr11:46830575 T/C cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs7246657 0.882 rs10412043 chr19:37826626 A/C cg18154014 chr19:37997991 ZNF793 0.72 5.18 0.42 8.64e-7 Coronary artery calcification; TGCT cis rs4786125 0.587 rs12920700 chr16:6926397 C/T cg03623568 chr16:6915990 A2BP1 -0.43 -6.42 -0.5 2.62e-9 Heart rate variability traits (SDNN); TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg11965913 chr1:205819406 PM20D1 0.49 6.62 0.51 9.88e-10 Menarche (age at onset); TGCT cis rs12510870 0.599 rs28407399 chr4:74448433 T/G cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs8008270 0.648 rs17125955 chr14:53406442 T/C cg01926858 chr14:53619558 DDHD1 -0.76 -4.61 -0.38 9.89e-6 Prostate cancer; TGCT cis rs2594989 0.623 rs6802055 chr3:11470642 T/A cg00170343 chr3:11313890 ATG7 0.86 5.27 0.43 5.97e-7 Circulating chemerin levels; TGCT cis rs4372836 0.715 rs66904522 chr2:29080892 A/C cg09522027 chr2:28974177 PPP1CB 0.67 6.94 0.53 1.89e-10 Body mass index; TGCT cis rs4499344 0.526 rs17832981 chr19:33034461 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.7 6.0 0.47 2.03e-8 Mean platelet volume; TGCT cis rs1552244 0.882 rs34779351 chr3:10021801 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs4595586 0.545 rs925829 chr12:39364167 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs28595532 0.920 rs114928651 chr4:119734194 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg03303774 chr4:1407052 NA -0.32 -4.92 -0.4 2.7e-6 Obesity-related traits; TGCT cis rs9486719 1.000 rs12205655 chr6:96891733 T/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs1997103 1.000 rs6973450 chr7:55396537 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs12220898 0.749 rs4838377 chr10:50488101 C/G cg06072769 chr10:50146962 WDFY4 0.36 4.78 0.39 4.88e-6 Inflammatory biomarkers; TGCT cis rs6733011 0.628 rs10188156 chr2:99465875 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.47 -4.68 -0.39 7.34e-6 Bipolar disorder; TGCT cis rs651907 0.557 rs34181125 chr3:101490278 A/G cg11279151 chr3:101281821 RG9MTD1 -0.32 -6.66 -0.51 7.93e-10 Colorectal cancer; TGCT cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg05985448 chr10:134359359 INPP5A 0.22 4.92 0.4 2.74e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs921968 1.000 rs921968 chr2:219272294 G/T cg02176678 chr2:219576539 TTLL4 0.34 4.82 0.4 4.05e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs4665809 1.000 rs7588802 chr2:26277789 A/G cg04944784 chr2:26401820 FAM59B -0.67 -6.05 -0.48 1.62e-8 Gut microbiome composition (summer); TGCT cis rs12950390 0.853 rs8071192 chr17:45856141 A/G cg24803719 chr17:45855879 NA -0.5 -5.12 -0.42 1.15e-6 IgG glycosylation; TGCT cis rs2013441 1.000 rs34712254 chr17:20049308 C/T cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs1371867 0.846 rs1788191 chr8:101260844 C/T cg06002616 chr8:101225028 SPAG1 0.57 6.77 0.52 4.48e-10 Atrioventricular conduction; TGCT cis rs782590 0.935 rs782649 chr2:55860308 T/C cg03859395 chr2:55845619 SMEK2 0.94 11.41 0.72 4.58e-21 Metabolic syndrome; TGCT cis rs7010267 0.869 rs1982763 chr8:119947828 C/T cg17171407 chr8:119960777 TNFRSF11B -0.33 -6.2 -0.49 7.72e-9 Total body bone mineral density (age 45-60); TGCT cis rs7246657 0.722 rs2972438 chr19:38210847 A/G cg18154014 chr19:37997991 ZNF793 0.74 5.28 0.43 5.63e-7 Coronary artery calcification; TGCT cis rs9902453 0.765 rs6505143 chr17:28150585 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 7.95 0.58 9.99e-13 Coffee consumption (cups per day); TGCT cis rs7726839 0.540 rs28364691 chr5:664084 G/A cg09021430 chr5:549028 NA -0.4 -5.64 -0.45 1.08e-7 Obesity-related traits; TGCT cis rs4638749 1.000 rs1466211 chr2:108856412 G/A cg06795125 chr2:108905320 SULT1C2 -0.39 -4.81 -0.4 4.26e-6 Blood pressure; TGCT cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2229238 0.911 rs6681207 chr1:154517217 T/C cg13067139 chr1:155221277 FAM189B 0.21 4.48 0.37 1.68e-5 Coronary heart disease; TGCT cis rs1670533 1.000 rs7669399 chr4:1058478 T/G cg27284194 chr4:1044797 NA 0.68 5.88 0.47 3.56e-8 Recombination rate (females); TGCT cis rs7010267 0.744 rs2062377 chr8:120007420 T/A cg17171407 chr8:119960777 TNFRSF11B 0.28 5.14 0.42 1.03e-6 Total body bone mineral density (age 45-60); TGCT cis rs7666738 0.830 rs13101352 chr4:98957544 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.877 rs10476597 chr5:93367172 C/T cg21475434 chr5:93447410 FAM172A -0.69 -4.97 -0.41 2.21e-6 Diabetic retinopathy; TGCT cis rs7095607 0.813 rs2087345 chr10:69922843 T/C cg18986048 chr10:69913749 MYPN 0.48 5.57 0.45 1.54e-7 Lung function (FVC); TGCT cis rs2404602 0.684 rs12437981 chr15:76842401 A/G cg23625390 chr15:77176239 SCAPER -0.38 -4.68 -0.39 7.3e-6 Blood metabolite levels; TGCT cis rs72717009 0.825 rs7529225 chr1:161479352 G/A cg23840854 chr1:161414152 NA -0.97 -5.65 -0.45 1.03e-7 Rheumatoid arthritis; TGCT cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9653442 0.593 rs7597861 chr2:100853187 G/A cg22139774 chr2:100720529 AFF3 -0.39 -6.33 -0.49 4.13e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs35000415 0.938 rs12535158 chr7:128625019 C/T cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs4765905 0.500 rs2239033 chr12:2337746 C/A cg07807026 chr12:2041581 NA -0.25 -4.45 -0.37 1.91e-5 Schizophrenia; TGCT cis rs8072100 1.000 rs4794048 chr17:45763073 A/C cg08085267 chr17:45401833 C17orf57 -0.43 -4.73 -0.39 6.01e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs425277 0.628 rs3107145 chr1:2047547 G/A cg03732007 chr1:2071316 PRKCZ -0.28 -6.2 -0.49 7.52e-9 Height; TGCT cis rs4972806 0.775 rs2857534 chr2:177035676 G/T cg03152288 chr2:177042942 NA 0.62 5.45 0.44 2.6e-7 IgG glycosylation; TGCT cis rs644799 0.648 rs1016031 chr11:95473365 C/T cg03916912 chr11:95522834 CEP57;FAM76B -0.56 -5.44 -0.44 2.69e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1371867 0.846 rs1660338 chr8:101242757 C/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.86 -0.4 3.42e-6 Atrioventricular conduction; TGCT cis rs7412746 0.646 rs10399947 chr1:150861960 G/A cg09365446 chr1:150670422 GOLPH3L 0.34 4.81 0.4 4.33e-6 Melanoma; TGCT cis rs2456568 0.802 rs1108910 chr11:93629677 C/T cg16099599 chr11:93583650 C11orf90 0.41 4.99 0.41 2.03e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs8017423 0.529 rs12898020 chr14:90835752 A/G cg04374321 chr14:90722782 PSMC1 -0.53 -4.7 -0.39 6.71e-6 Mortality in heart failure; TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg22166914 chr1:53195759 ZYG11B 0.3 4.95 0.41 2.41e-6 Monocyte count; TGCT cis rs8051149 0.793 rs12445334 chr16:87871213 G/A cg01412419 chr16:87856264 NA 0.49 5.79 0.46 5.38e-8 Blood metabolite levels; TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs7714584 1.000 rs7724558 chr5:150328866 T/C cg22134413 chr5:150180641 NA 0.89 5.24 0.43 6.8e-7 Crohn's disease; TGCT cis rs13064411 0.542 rs9846539 chr3:113228688 A/G cg18753928 chr3:113234510 CCDC52 -0.56 -4.72 -0.39 6.3e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs4900538 0.821 rs2009575 chr14:102820787 C/T cg18135206 chr14:102964638 TECPR2 -0.22 -5.09 -0.42 1.31e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9467773 0.595 rs2237236 chr6:26451553 A/G cg05738196 chr6:26577821 NA -0.51 -5.51 -0.44 2.03e-7 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.577 rs41270271 chr1:15913582 G/C cg05660106 chr1:15850417 CASP9 1.05 11.89 0.73 3.11e-22 Systolic blood pressure; TGCT cis rs2721811 0.570 rs2721803 chr7:24781532 C/T cg17569154 chr7:24781545 DFNA5 0.22 4.77 0.39 5.15e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1371867 0.846 rs1660327 chr8:101292206 A/C cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg02487422 chr3:49467188 NICN1 0.49 4.46 0.37 1.85e-5 Parkinson's disease; TGCT cis rs2288884 0.708 rs59104696 chr19:52555170 C/T cg15405931 chr19:52693188 PPP2R1A -0.64 -4.5 -0.38 1.51e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs12477438 0.765 rs28648058 chr2:99696417 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.8 -8.02 -0.58 6.63e-13 Chronic sinus infection; TGCT cis rs763121 0.853 rs6001191 chr22:39074452 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs2456568 0.508 rs1607403 chr11:93660514 A/G cg26875233 chr11:93583750 C11orf90 -0.41 -4.97 -0.41 2.14e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10504229 0.683 rs16921808 chr8:58106049 C/T cg21724239 chr8:58056113 NA 0.45 4.8 0.4 4.39e-6 Developmental language disorder (linguistic errors); TGCT trans rs7824557 0.564 rs2736293 chr8:11234613 T/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.42e-10 Retinal vascular caliber; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg04234412 chr22:24373322 LOC391322 -0.86 -9.6 -0.65 1.17e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg11905131 chr22:24372483 LOC391322 0.94 11.12 0.71 2.42e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2933343 0.621 rs789241 chr3:128585752 G/A cg11901034 chr3:128598214 ACAD9 -0.64 -6.16 -0.48 9.37e-9 IgG glycosylation; TGCT cis rs2456568 0.900 rs2000960 chr11:93682348 C/T cg14065697 chr11:93583672 C11orf90 -0.38 -4.58 -0.38 1.13e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs41271951 0.512 rs12058128 chr1:151106113 C/T cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs9611565 0.527 rs2234053 chr22:41777315 G/T cg13695892 chr22:41940480 POLR3H -0.92 -9.33 -0.64 5.22e-16 Vitiligo; TGCT cis rs9916302 0.706 rs9906612 chr17:37547631 A/C cg07936489 chr17:37558343 FBXL20 0.86 6.12 0.48 1.15e-8 Glomerular filtration rate (creatinine); TGCT cis rs769267 1.000 rs2074090 chr19:19449686 G/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT trans rs608114 0.623 rs507546 chr6:96375839 C/T cg04008557 chr11:2826328 KCNQ1 -0.65 -6.82 -0.52 3.51e-10 Response to abacavir-containing treatment in HIV-1 infection (virologic failure);Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs3771570 0.786 rs62186396 chr2:242221219 A/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg17971929 chr21:40555470 PSMG1 0.97 9.54 0.65 1.63e-16 Cognitive function; TGCT cis rs2204008 0.614 rs4578492 chr12:38036350 T/C cg13010199 chr12:38710504 ALG10B 0.65 5.23 0.42 7.11e-7 Bladder cancer; TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs2562456 0.874 rs2562417 chr19:21711202 T/C cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT trans rs12599106 0.679 rs34584967 chr16:34475725 T/G cg01516881 chr6:292596 DUSP22 -0.71 -7.54 -0.56 8.6e-12 Menopause (age at onset); TGCT cis rs3820068 0.577 rs9728986 chr1:16040603 G/A cg17385448 chr1:15911702 AGMAT 0.35 4.99 0.41 1.96e-6 Systolic blood pressure; TGCT cis rs4727027 0.933 rs1044358 chr7:148879951 C/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.77 0.39 5.16e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2239785 0.920 rs136154 chr22:36656138 A/T cg15716373 chr22:36655542 APOL1 -0.41 -4.75 -0.39 5.58e-6 Glomerulosclerosis; TGCT cis rs2836950 0.565 rs2150413 chr21:40614878 C/T cg11644478 chr21:40555479 PSMG1 -0.53 -4.96 -0.41 2.23e-6 Menarche (age at onset); TGCT cis rs6426551 0.958 rs6702917 chr1:226547174 C/T cg18564989 chr1:226411057 MIXL1 -0.48 -4.8 -0.4 4.44e-6 Coronary artery disease; TGCT cis rs3806843 0.648 rs2530233 chr5:140082876 A/G cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2172802 1.000 rs12642315 chr4:62448934 C/G cg04118610 chr4:62707027 LPHN3 -0.41 -4.83 -0.4 3.92e-6 Partial epilepsies; TGCT cis rs225245 0.817 rs225255 chr17:33955243 A/G cg05299278 chr17:33885742 SLFN14 -0.21 -4.64 -0.38 8.76e-6 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs28595532 0.841 rs115725150 chr4:119768647 T/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs9291683 0.507 rs3775940 chr4:10025163 A/T cg11266682 chr4:10021025 SLC2A9 0.64 8.48 0.61 5.5e-14 Bone mineral density; TGCT cis rs524281 0.861 rs7935336 chr11:65865325 C/T cg00563793 chr11:65837595 PACS1 0.55 4.62 0.38 9.44e-6 Electroencephalogram traits; TGCT cis rs826838 0.967 rs10875979 chr12:39095149 G/A cg13010199 chr12:38710504 ALG10B 0.71 5.78 0.46 5.59e-8 Heart rate; TGCT cis rs9427116 0.702 rs884618 chr1:154601157 A/G cg17218026 chr1:154582156 ADAR 0.28 7.06 0.54 1.06e-10 Blood protein levels; TGCT cis rs6500602 0.702 rs2058812 chr16:4524443 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.26 4.86 0.4 3.44e-6 Schizophrenia; TGCT cis rs3125734 0.633 rs10740068 chr10:63982254 A/C cg19640130 chr10:64028056 RTKN2 -0.39 -5.11 -0.42 1.19e-6 Rheumatoid arthritis; TGCT cis rs910316 1.000 rs2268617 chr14:75608728 G/A cg23033748 chr14:75592666 NEK9 0.29 4.9 0.4 2.95e-6 Height; TGCT cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs3806843 0.576 rs246007 chr5:140338748 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7267979 1.000 rs2257420 chr20:25275890 C/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1416584 1.000 rs12683691 chr9:8220627 T/A cg26401796 chr12:5574420 NTF3 0.6 6.85 0.52 3.04e-10 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs899997 1.000 rs11629824 chr15:79005524 T/G cg00061860 chr15:78953028 NA -0.25 -4.61 -0.38 9.69e-6 Coronary artery disease or large artery stroke; TGCT cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg07636037 chr3:49044803 WDR6 0.88 9.28 0.64 6.89e-16 Menarche (age at onset); TGCT cis rs854765 0.583 rs62064158 chr17:17826935 T/C cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs28595532 0.920 rs56303276 chr4:119723514 C/T cg21605333 chr4:119757512 SEC24D 1.72 8.99 0.63 3.52e-15 Cannabis dependence symptom count; TGCT cis rs6840360 1.000 rs10007015 chr4:152603528 C/G cg17479576 chr4:152424074 FAM160A1 -0.48 -5.16 -0.42 9.63e-7 Intelligence (multi-trait analysis); TGCT cis rs896854 0.846 rs7845219 chr8:95937502 T/C cg09323728 chr8:95962352 TP53INP1 -0.52 -6.69 -0.52 6.78e-10 Type 2 diabetes; TGCT cis rs7258465 0.931 rs7249020 chr19:18608147 A/G cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs896854 0.625 rs7823886 chr8:95986459 A/T cg09323728 chr8:95962352 TP53INP1 -0.51 -6.46 -0.5 2.13e-9 Type 2 diabetes; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg04234412 chr22:24373322 LOC391322 0.93 11.89 0.73 3.2e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6582630 0.555 rs10880544 chr12:38473464 G/C cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12701220 0.894 rs2141274 chr7:1034717 G/A cg07217954 chr7:1067459 C7orf50 -0.49 -4.89 -0.4 3.09e-6 Bronchopulmonary dysplasia; TGCT cis rs2836974 0.627 rs8127986 chr21:40687211 A/T cg11644478 chr21:40555479 PSMG1 -0.57 -4.86 -0.4 3.44e-6 Cognitive function; TGCT cis rs35883536 0.588 rs10465764 chr1:101105030 A/G cg06223162 chr1:101003688 GPR88 0.33 5.41 0.44 3.15e-7 Monocyte count; TGCT cis rs709400 0.628 rs7154246 chr14:103876794 G/A cg12935359 chr14:103987150 CKB 0.34 5.19 0.42 8.36e-7 Body mass index; TGCT cis rs5769707 0.681 rs8140095 chr22:50043795 A/G cg06623630 chr22:50017776 C22orf34 -0.27 -4.67 -0.39 7.81e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7267979 1.000 rs2258135 chr20:25272323 C/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854765 0.547 rs4643387 chr17:17972973 C/T cg09796270 chr17:17721594 SREBF1 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs8014252 0.803 rs10135356 chr14:71030355 T/C cg11204974 chr14:71022665 NA -0.53 -4.49 -0.37 1.63e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs36051895 0.695 rs12347727 chr9:5000811 A/G cg02405213 chr9:5042618 JAK2 -0.76 -10.04 -0.67 1e-17 Pediatric autoimmune diseases; TGCT cis rs1008375 0.931 rs2315558 chr4:17674558 C/A cg18681998 chr4:17616180 MED28 0.93 10.58 0.69 4.83e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7772486 0.875 rs2814869 chr6:146315509 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.13 0.42 1.1e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4713118 0.699 rs200978 chr6:27853168 C/G cg18675097 chr6:28227127 NKAPL -0.35 -4.47 -0.37 1.72e-5 Parkinson's disease; TGCT cis rs2836950 0.565 rs2836926 chr21:40536790 G/A cg17971929 chr21:40555470 PSMG1 -0.51 -4.55 -0.38 1.25e-5 Menarche (age at onset); TGCT cis rs634534 0.563 rs470192 chr11:65724291 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.6 6.03 0.48 1.75e-8 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs11190604 1.000 rs11190569 chr10:102227409 C/T cg16342193 chr10:102329863 NA -0.41 -5.44 -0.44 2.67e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1723838 0.826 rs1466218 chr11:73589184 G/T cg18195628 chr11:73498948 MRPL48 0.93 4.55 0.38 1.28e-5 Obesity-related traits; TGCT cis rs1580019 0.523 rs13236410 chr7:32690663 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 13.49 0.77 4.38e-26 Cognitive ability; TGCT cis rs17253792 0.822 rs17683728 chr14:56060389 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7843479 0.965 rs9314269 chr8:21804989 A/G cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs4478037 1.000 rs4074417 chr3:33161153 A/C cg19404215 chr3:33155277 CRTAP 1.28 8.55 0.61 3.75e-14 Major depressive disorder; TGCT cis rs6570726 0.791 rs9497357 chr6:145912888 G/A cg23711669 chr6:146136114 FBXO30 0.88 9.32 0.64 5.56e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7523273 0.565 rs4081159 chr1:207885479 G/A cg22525895 chr1:207977042 MIR29B2 0.35 5.69 0.45 8.78e-8 Schizophrenia; TGCT cis rs826838 0.967 rs7963716 chr12:38876090 C/T cg26384229 chr12:38710491 ALG10B 0.94 9.68 0.66 7.64e-17 Heart rate; TGCT cis rs4699052 0.625 rs11097808 chr4:104263130 G/A cg16532752 chr4:104119610 CENPE -0.5 -4.92 -0.4 2.71e-6 Testicular germ cell tumor; TGCT cis rs13191362 0.935 rs67673890 chr6:163107647 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.16 9.92 0.67 1.96e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11112613 0.775 rs7299470 chr12:105961773 G/A cg03607813 chr12:105948248 NA 0.46 5.56 0.45 1.6e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7635838 0.819 rs2454476 chr3:11545442 G/A cg00170343 chr3:11313890 ATG7 0.67 6.13 0.48 1.1e-8 HDL cholesterol; TGCT cis rs6693567 0.565 rs4926395 chr1:150405298 T/C cg09579323 chr1:150459698 TARS2 0.52 4.6 0.38 1.03e-5 Migraine; TGCT cis rs9549367 0.713 rs9549356 chr13:113851633 A/G cg18105134 chr13:113819100 PROZ -0.46 -8.3 -0.6 1.46e-13 Platelet distribution width; TGCT cis rs116095464 0.558 rs9312957 chr5:202194 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.73 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs7666738 0.753 rs4699604 chr4:99056353 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9467711 0.790 rs10484439 chr6:26309908 G/A cg05948654 chr6:25930507 SLC17A2 0.34 4.54 0.38 1.29e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6754311 0.593 rs1438305 chr2:136502792 C/G cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Mosquito bite size; TGCT trans rs6089829 0.962 rs6062780 chr20:61666648 T/C cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs765787 0.530 rs4775844 chr15:45542048 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs28386778 0.897 rs2727290 chr17:61894728 G/T cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs7647973 0.710 rs6446284 chr3:49616997 A/G cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs7772486 0.875 rs2777481 chr6:146310036 G/T cg05347473 chr6:146136440 FBXO30 0.51 4.76 0.39 5.34e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs6089829 0.962 rs2277768 chr20:61666823 T/C cg23505145 chr19:12996616 KLF1 0.76 7.98 0.58 8.44e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2637266 1.000 rs2130799 chr10:78322922 C/T cg18941641 chr10:78392320 NA 0.38 4.72 0.39 6.21e-6 Pulmonary function; TGCT cis rs2153535 0.580 rs2152347 chr6:8474281 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs42648 0.935 rs42659 chr7:89981958 A/G cg25739043 chr7:89950458 NA -0.65 -6.22 -0.49 6.96e-9 Homocysteine levels; TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs7043114 0.525 rs10283572 chr9:95133074 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.58 -0.45 1.42e-7 Height; TGCT cis rs7833790 0.636 rs12544174 chr8:82731477 G/A cg27398817 chr8:82754497 SNX16 -0.67 -5.34 -0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs9640161 0.789 rs2373751 chr7:150021599 G/C cg10018233 chr7:150070692 REPIN1 0.32 4.58 0.38 1.1e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs73058052 0.569 rs2116922 chr19:50103252 G/A cg09250473 chr19:50168907 IRF3;BCL2L12 0.68 5.58 0.45 1.42e-7 Fibrinogen levels; TGCT cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg20607798 chr8:58055168 NA 0.45 4.59 0.38 1.06e-5 Developmental language disorder (linguistic errors); TGCT cis rs9911578 0.900 rs8067264 chr17:57182793 G/C cg12560992 chr17:57184187 TRIM37 0.79 9.71 0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs17030434 0.815 rs78638854 chr4:154648804 C/T cg14289246 chr4:154710475 SFRP2 -0.85 -6.45 -0.5 2.28e-9 Electrocardiographic conduction measures; TGCT cis rs4563143 0.514 rs73029076 chr19:29292032 G/T cg04546413 chr19:29218101 NA 0.73 5.38 0.43 3.65e-7 Methadone dose in opioid dependence; TGCT cis rs875971 0.619 rs2302918 chr7:66000932 A/G cg18876405 chr7:65276391 NA 0.36 5.44 0.44 2.7e-7 Aortic root size; TGCT cis rs17601876 0.786 rs2414100 chr15:51562420 T/A cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs76788097 0.614 rs7151034 chr14:61820669 T/G cg11001769 chr14:61748440 TMEM30B -0.52 -4.55 -0.38 1.24e-5 Marginal zone lymphoma; TGCT cis rs933688 1.000 rs10474353 chr5:90732285 A/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 8.86 0.62 7.17e-15 Smoking behavior; TGCT cis rs6495367 1.000 rs1007366 chr15:79379541 G/A cg17916960 chr15:79447300 NA 0.36 5.12 0.42 1.14e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs6088580 0.634 rs1205334 chr20:32930369 T/C cg08999081 chr20:33150536 PIGU -0.26 -4.98 -0.41 2.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs4730250 0.707 rs10953537 chr7:107027905 G/A cg02696742 chr7:106810147 HBP1 -0.67 -5.36 -0.43 3.86e-7 Osteoarthritis; TGCT cis rs7582180 0.700 rs4851303 chr2:100962064 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs7104764 0.957 rs3782120 chr11:206089 G/A cg18336825 chr11:236787 PSMD13;SIRT3 -1.02 -10.55 -0.69 5.9e-19 Menarche (age at onset); TGCT cis rs9436747 0.667 rs6657632 chr1:66038666 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.88 0.4 3.21e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs13217239 0.574 rs9366680 chr6:27006123 A/T cg02458000 chr6:26745757 NA 0.49 4.6 0.38 1.03e-5 Schizophrenia; TGCT trans rs941408 1.000 rs1640272 chr19:2800192 A/T cg19676328 chr12:49525230 TUBA1B -0.71 -6.93 -0.53 2.07e-10 Total cholesterol levels; TGCT cis rs72634258 0.554 rs35123409 chr1:7878568 C/T cg26816564 chr1:7831052 VAMP3 0.87 6.3 0.49 4.76e-9 Inflammatory bowel disease; TGCT cis rs875971 0.862 rs10224872 chr7:65759773 T/A cg11764359 chr7:65958608 NA -0.57 -5.07 -0.41 1.4e-6 Aortic root size; TGCT cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg17554472 chr22:41940697 POLR3H -0.52 -5.37 -0.43 3.79e-7 Vitiligo; TGCT cis rs151997 0.962 rs27273 chr5:50181074 G/A cg06027927 chr5:50259733 NA 0.46 4.61 0.38 9.69e-6 Callous-unemotional behaviour; TGCT cis rs1153858 1.000 rs12594857 chr15:45667178 A/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs4499344 0.623 rs11670818 chr19:33099854 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.81 8.12 0.59 3.9e-13 Mean platelet volume; TGCT cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg09904177 chr6:26538194 HMGN4 0.67 6.48 0.5 1.94e-9 Intelligence (multi-trait analysis); TGCT cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg12667521 chr19:29218732 NA 0.53 5.61 0.45 1.25e-7 Methadone dose in opioid dependence; TGCT trans rs3780486 0.846 rs6476399 chr9:33123013 A/G cg20290983 chr6:43655470 MRPS18A 1.21 15.13 0.81 5.99e-30 IgG glycosylation; TGCT cis rs7584330 0.826 rs72620825 chr2:238381243 G/A cg14458575 chr2:238380390 NA 0.61 9.36 0.64 4.53e-16 Prostate cancer; TGCT cis rs2230307 0.505 rs641458 chr1:100578672 G/C cg24955406 chr1:100503596 HIAT1 -0.77 -5.23 -0.43 6.91e-7 Carotid intima media thickness; TGCT cis rs1372520 0.627 rs2583964 chr4:90727218 A/G cg26578617 chr4:90757533 SNCA -0.52 -4.44 -0.37 1.99e-5 Neuroticism; TGCT cis rs17741873 0.779 rs4746154 chr10:75629396 G/A cg07699608 chr10:75541558 CHCHD1 0.79 5.64 0.45 1.07e-7 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg09904177 chr6:26538194 HMGN4 0.67 6.3 0.49 4.72e-9 Intelligence (multi-trait analysis); TGCT cis rs4455778 0.536 rs38774 chr7:48939388 C/T cg26309511 chr7:48887640 NA 0.48 5.68 0.45 9.01e-8 Lung cancer in never smokers; TGCT cis rs7959452 0.535 rs2305641 chr12:69646914 C/T cg20891283 chr12:69753455 YEATS4 0.63 6.09 0.48 1.32e-8 Blood protein levels; TGCT cis rs17122693 0.748 rs8014572 chr14:51095780 C/A cg04730355 chr14:51134070 SAV1 1.24 10.9 0.7 8.04e-20 Cognitive performance; TGCT cis rs2243480 0.803 rs34804747 chr7:65412942 G/C cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs7666738 0.830 rs13137808 chr4:99047095 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.967 rs13149715 chr4:1278255 C/A cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs7698623 0.850 rs4693891 chr4:88787834 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs1215050 0.791 rs11729826 chr4:98657190 G/T cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs67311347 0.955 rs11719205 chr3:40417258 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs9788682 0.948 rs28498264 chr15:78837673 C/T cg24631222 chr15:78858424 CHRNA5 0.94 7.61 0.56 5.94e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs11190604 1.000 rs2489035 chr10:102319395 C/T cg16342193 chr10:102329863 NA -0.39 -5.0 -0.41 1.92e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12762955 0.561 rs2620942 chr10:1048398 C/T cg26597838 chr10:835615 NA 0.47 6.32 0.49 4.23e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs4851251 1.000 rs62150284 chr2:100784118 T/C cg07810366 chr2:100720526 AFF3 0.39 5.1 0.42 1.22e-6 Educational attainment (years of education); TGCT cis rs1215050 0.791 rs10856931 chr4:98819306 C/T cg17366294 chr4:99064904 C4orf37 0.56 6.05 0.48 1.57e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg20887711 chr4:1340912 KIAA1530 0.95 8.36 0.6 1.08e-13 Longevity; TGCT cis rs1865760 1.000 rs7770139 chr6:25925823 A/G cg16482183 chr6:26056742 HIST1H1C 0.51 4.59 0.38 1.06e-5 Height; TGCT cis rs1577917 0.958 rs2324817 chr6:86462654 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.27 -0.43 5.96e-7 Response to antipsychotic treatment; TGCT cis rs7226408 0.901 rs10502671 chr18:34741111 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs651907 0.535 rs4342086 chr3:101503765 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs11864453 0.713 rs9925763 chr16:72142595 C/A cg14768367 chr16:72042858 DHODH 0.52 4.98 0.41 2.04e-6 Fibrinogen levels; TGCT cis rs10876993 0.928 rs1689587 chr12:58075398 A/G cg15848620 chr12:58087721 OS9 -0.71 -5.77 -0.46 5.92e-8 Celiac disease or Rheumatoid arthritis; TGCT trans rs2688482 0.512 rs3103954 chr3:195516630 G/T cg17952111 chr19:54960355 LENG8 0.84 6.99 0.53 1.52e-10 Lung disease severity in cystic fibrosis; TGCT cis rs72781680 0.678 rs11125293 chr2:24102423 A/G cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs7584330 0.826 rs7604315 chr2:238381729 C/G cg08992911 chr2:238395768 MLPH 0.61 4.75 0.39 5.62e-6 Prostate cancer; TGCT cis rs1334894 1.000 rs12527893 chr6:35585099 T/C cg24281267 chr6:35479648 TULP1 -0.44 -4.73 -0.39 5.95e-6 Coronary artery disease; TGCT cis rs9830388 0.584 rs3104243 chr3:23463993 C/T cg25382821 chr3:23496403 UBE2E2 0.25 4.53 0.38 1.38e-5 RR interval (tricyclic/tetracyclic antidepressant use interaction); TGCT cis rs1783925 1.000 rs610236 chr11:125297925 T/A cg03464685 chr11:125439445 EI24 -0.55 -4.55 -0.38 1.24e-5 Formal thought disorder in schizophrenia; TGCT cis rs7681440 0.669 rs7693616 chr4:90792230 G/T cg10208370 chr4:90758469 SNCA 0.55 5.09 0.42 1.31e-6 Dementia with Lewy bodies; TGCT cis rs1577917 0.958 rs13207354 chr6:86700263 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs642803 0.613 rs489574 chr11:65542739 C/T cg27068330 chr11:65405492 SIPA1 0.64 5.69 0.46 8.6e-8 Urate levels; TGCT cis rs10514758 0.744 rs34711605 chr3:114924122 T/G cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs46522 0.585 rs79049364 chr17:47014991 T/A cg26022315 chr17:47021804 SNF8 0.52 5.17 0.42 9.24e-7 Coronary heart disease; TGCT cis rs75646498 0.571 rs77241922 chr15:29859371 T/A cg08904058 chr15:29859427 FAM189A1 -0.47 -4.53 -0.38 1.38e-5 Diisocyanate-induced asthma; TGCT cis rs3087591 0.920 rs4795571 chr17:29398369 G/A cg24425628 chr17:29625626 OMG;NF1 0.49 7.4 0.55 1.76e-11 Hip circumference; TGCT cis rs7208859 0.614 rs216412 chr17:28903394 A/G cg14008862 chr17:28927542 LRRC37B2 -0.74 -4.8 -0.4 4.44e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs514406 0.505 rs447581 chr1:53177098 T/C cg22166914 chr1:53195759 ZYG11B 0.45 7.99 0.58 7.98e-13 Monocyte count; TGCT trans rs17277593 0.517 rs34414566 chr9:13875448 G/A cg24852548 chr4:57522632 HOPX 0.73 6.82 0.52 3.57e-10 Endometriosis; TGCT cis rs514406 0.861 rs4926932 chr1:53247495 C/T cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs6840360 0.615 rs6836249 chr4:152465829 T/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs2688608 0.592 rs11000757 chr10:75486815 T/C cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs7017914 0.905 rs3110257 chr8:71938151 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs9916302 0.821 rs12938268 chr17:37572139 G/A cg07936489 chr17:37558343 FBXL20 -0.63 -4.91 -0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs858239 1.000 rs166663 chr7:23316742 A/C cg05602783 chr7:23145260 KLHL7 -0.55 -4.46 -0.37 1.85e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs909674 0.690 rs1972280 chr22:39831986 T/A cg01416388 chr22:39784598 NA -0.74 -6.78 -0.52 4.37e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6089829 0.962 rs6011544 chr20:61658782 T/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs6088580 0.634 rs4277599 chr20:33008905 A/G cg06115741 chr20:33292138 TP53INP2 -0.51 -4.44 -0.37 1.98e-5 Glomerular filtration rate (creatinine); TGCT cis rs826838 0.872 rs826878 chr12:39088837 A/T cg13010199 chr12:38710504 ALG10B -0.56 -4.6 -0.38 1.04e-5 Heart rate; TGCT cis rs7727544 0.642 rs7705189 chr5:131623358 C/T cg24060327 chr5:131705240 SLC22A5 0.51 4.94 0.41 2.48e-6 Blood metabolite levels; TGCT cis rs1215050 0.669 rs783962 chr4:98884473 G/A cg05340658 chr4:99064831 C4orf37 -0.45 -5.47 -0.44 2.39e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9926296 0.546 rs6500442 chr16:89828862 T/C cg04287289 chr16:89883240 FANCA 0.92 11.69 0.72 9.94e-22 Vitiligo; TGCT cis rs6089829 0.925 rs6062396 chr20:61667949 T/C cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT trans rs2688608 0.592 rs7909802 chr10:75484186 G/C cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs2777491 0.872 rs11267024 chr15:41576241 C/T cg18705301 chr15:41695430 NDUFAF1 -0.71 -9.22 -0.64 9.96e-16 Ulcerative colitis; TGCT cis rs6540559 0.673 rs17317411 chr1:209961314 C/T cg23283495 chr1:209979779 IRF6 -0.63 -4.59 -0.38 1.07e-5 Cleft lip with or without cleft palate; TGCT cis rs113084984 0.642 rs13021546 chr2:11681043 G/T cg25804072 chr2:10829725 NOL10 0.52 4.58 0.38 1.1e-5 Breast cancer; TGCT cis rs17711722 0.565 rs4717276 chr7:65294741 G/T cg20849893 chr7:64541193 NA 0.5 5.22 0.42 7.27e-7 Calcium levels; TGCT cis rs526231 0.747 rs39984 chr5:102597292 G/T cg05225461 chr5:102596755 C5orf30 0.22 4.49 0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs3096299 0.685 rs4329923 chr16:89560178 C/T cg08392591 chr16:89556376 ANKRD11 0.53 5.0 0.41 1.89e-6 Multiple myeloma (IgH translocation); TGCT cis rs11190604 1.000 rs4919465 chr10:102221703 C/T cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12681287 0.640 rs34794500 chr8:87449995 G/A cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs8062405 0.824 rs28698667 chr16:28533071 C/T cg09754948 chr16:28834200 ATXN2L 0.58 4.57 0.38 1.14e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT trans rs4650994 0.625 rs6681348 chr1:178526271 A/C cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.37e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs4788439 0.901 rs8049531 chr16:24979232 G/A cg07626409 chr16:25250191 ZKSCAN2 0.32 4.45 0.37 1.87e-5 Blood metabolite levels; TGCT cis rs35000415 0.566 rs35144535 chr7:128721777 A/G cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs7824557 0.564 rs55758514 chr8:11230259 A/T cg21775007 chr8:11205619 TDH -0.61 -5.82 -0.46 4.66e-8 Retinal vascular caliber; TGCT cis rs9790314 0.871 rs466626 chr3:161103629 A/C cg03342759 chr3:160939853 NMD3 -0.47 -4.96 -0.41 2.23e-6 Morning vs. evening chronotype; TGCT cis rs1534166 0.601 rs13324779 chr3:133510413 G/A cg16414030 chr3:133502952 NA 0.45 5.81 0.46 4.92e-8 Alcohol consumption (transferrin glycosylation); TGCT cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg25151919 chr3:44754333 ZNF502 -0.46 -5.48 -0.44 2.26e-7 Depressive symptoms; TGCT cis rs7666738 0.830 rs28878289 chr4:98855181 C/T cg05340658 chr4:99064831 C4orf37 0.52 6.0 0.47 1.98e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6893807 0.778 rs16903285 chr5:87978252 T/C cg24804195 chr5:87968844 LOC645323 0.78 4.6 0.38 1.04e-5 Body mass index; TGCT cis rs11148252 0.755 rs116860555 chr13:52936937 C/T cg00495681 chr13:53174319 NA -0.49 -4.64 -0.38 8.75e-6 Lewy body disease; TGCT cis rs2562456 0.874 rs9304986 chr19:21682062 G/A cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs12477438 0.765 rs17708262 chr2:99696313 T/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.61 -5.23 -0.43 6.94e-7 Chronic sinus infection; TGCT cis rs36051895 0.632 rs7029084 chr9:5174638 T/C cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.34e-20 Pediatric autoimmune diseases; TGCT cis rs6840360 0.615 rs6535816 chr4:152614264 T/C cg22705602 chr4:152727874 NA -0.36 -6.01 -0.48 1.91e-8 Intelligence (multi-trait analysis); TGCT cis rs7107174 0.688 rs11237489 chr11:78130325 G/A cg12700464 chr11:78128424 GAB2 -0.67 -4.46 -0.37 1.83e-5 Testicular germ cell tumor; TGCT cis rs7666738 0.753 rs4699604 chr4:99056353 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.92 0.47 2.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.791 rs6570692 chr6:145904401 T/A cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.899 rs2836938 chr21:40574191 C/T cg06238570 chr21:40685208 BRWD1 0.7 6.45 0.5 2.3e-9 Cognitive function; TGCT cis rs28595532 0.920 rs113034745 chr4:119750044 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs11577318 0.579 rs11548246 chr1:26697166 G/A cg15090202 chr1:26687087 NA 0.58 4.43 0.37 2.01e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs231513 0.681 rs35362475 chr17:42012813 C/A cg26893861 chr17:41843967 DUSP3 0.76 4.64 0.38 8.65e-6 Cognitive function; TGCT cis rs10875746 0.951 rs2228500 chr12:48526712 A/G cg20731937 chr12:48336164 NA -0.64 -5.02 -0.41 1.76e-6 Longevity (90 years and older); TGCT cis rs2439831 1.000 rs2264239 chr15:43765533 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs7666738 0.830 rs13139078 chr4:99020774 C/T cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.66 0.39 8.18e-6 Prudent dietary pattern; TGCT cis rs28595532 0.920 rs55633605 chr4:119761589 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs13102973 0.965 rs7656209 chr4:135875550 G/A cg14419869 chr4:135874104 NA 0.24 4.46 0.37 1.83e-5 Subjective well-being; TGCT cis rs9929218 0.859 rs9936682 chr16:68748223 A/G cg01251360 chr16:68772225 CDH1 0.31 5.03 0.41 1.67e-6 Colorectal cancer; TGCT cis rs7568458 0.709 rs762684 chr2:85782023 G/A cg17127132 chr2:85788382 GGCX 0.51 4.58 0.38 1.12e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10751667 0.643 rs7396046 chr11:937176 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.28 -0.6 1.65e-13 Alzheimer's disease (late onset); TGCT cis rs262150 0.502 rs73167295 chr7:158782949 T/A cg01219135 chr7:158766336 NA -0.44 -4.63 -0.38 9.13e-6 Facial morphology (factor 20); TGCT cis rs6866344 0.570 rs1071881 chr5:178135917 C/T cg10224037 chr5:178157518 ZNF354A 0.95 9.24 0.64 8.55e-16 Neutrophil percentage of white cells; TGCT cis rs6988636 1.000 rs13260798 chr8:124190192 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs7917772 0.502 rs4919670 chr10:104515799 C/A cg05855489 chr10:104503620 C10orf26 0.73 6.06 0.48 1.48e-8 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs79349575 0.811 rs1057897 chr17:47005509 T/G cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs2204008 0.775 rs12099736 chr12:38344111 C/G cg26384229 chr12:38710491 ALG10B 0.82 7.22 0.54 4.5e-11 Bladder cancer; TGCT cis rs7225537 0.559 rs4985730 chr17:17016726 T/C cg26176665 chr17:16994978 MPRIP 0.24 5.76 0.46 6.16e-8 Mean platelet volume; TGCT cis rs7178572 0.633 rs7162637 chr15:77843365 A/G cg22256960 chr15:77711686 NA -0.82 -7.51 -0.56 1.03e-11 Type 2 diabetes; TGCT cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs769267 0.930 rs2304098 chr19:19646272 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.66 5.43 0.44 2.84e-7 Tonsillectomy; TGCT cis rs478304 0.651 rs78412025 chr11:65495696 T/C cg27068330 chr11:65405492 SIPA1 -0.94 -9.4 -0.65 3.54e-16 Acne (severe); TGCT cis rs35000415 0.638 rs77508372 chr7:128721797 T/G cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs5769765 1.000 rs5770755 chr22:50280136 T/C cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.4e-22 Schizophrenia; TGCT cis rs7829975 0.514 rs2920991 chr8:8259117 T/A cg08975724 chr8:8085496 FLJ10661 0.56 5.01 0.41 1.82e-6 Mood instability; TGCT cis rs9311474 0.507 rs4687644 chr3:52746541 T/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs7772486 0.686 rs6570701 chr6:145954090 A/G cg13319975 chr6:146136371 FBXO30 -0.52 -4.78 -0.39 4.81e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10927875 0.688 rs2009371 chr1:16348083 A/T cg22431228 chr1:16359049 CLCNKA -0.25 -4.64 -0.38 8.84e-6 Dilated cardiomyopathy; TGCT cis rs7171869 1 rs7171869 chr15:78900909 A/G cg24631222 chr15:78858424 CHRNA5 -0.88 -6.66 -0.51 7.79e-10 Post bronchodilator FEV1; TGCT cis rs1997103 1.000 rs4947500 chr7:55407270 C/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7829975 0.509 rs7838674 chr8:8797073 A/T cg06636001 chr8:8085503 FLJ10661 -0.7 -6.19 -0.49 8.23e-9 Mood instability; TGCT cis rs908922 0.676 rs10888494 chr1:152514709 T/C cg20991723 chr1:152506922 NA 0.46 6.17 0.48 8.79e-9 Hair morphology; TGCT cis rs290268 1.000 rs290274 chr9:93546913 C/T cg02608019 chr9:93564028 SYK 0.49 4.89 0.4 3.09e-6 Platelet count; TGCT cis rs9364220 0.646 rs2029489 chr6:168496038 A/G cg02770688 chr6:168491649 NA -0.31 -5.88 -0.47 3.59e-8 Attention deficit hyperactivity disorder (inattention symptoms);Attention deficit hyperactivity disorder (combined symptoms); TGCT cis rs7954584 0.567 rs11612028 chr12:122387872 C/G cg22168489 chr12:122356033 WDR66 0.22 4.76 0.39 5.26e-6 Mean corpuscular volume; TGCT trans rs28735056 0.933 rs56181785 chr18:77633629 G/A cg05926928 chr17:57297772 GDPD1 -0.71 -7.55 -0.56 8.06e-12 Schizophrenia; TGCT cis rs10114408 0.959 rs10124030 chr9:96652310 T/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7937682 0.924 rs10891284 chr11:111527737 T/C cg09085632 chr11:111637200 PPP2R1B -1.12 -11.81 -0.73 4.86e-22 Primary sclerosing cholangitis; TGCT cis rs6076065 0.748 rs6048750 chr20:23334192 T/G cg11657817 chr20:23433608 CST11 0.31 5.29 0.43 5.46e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs9788333 0.888 rs35880230 chr13:21885972 A/G cg22663859 chr13:21900854 NA 0.36 4.99 0.41 1.97e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs12510870 0.588 rs10938085 chr4:74396579 A/G cg05868023 chr4:75230803 EREG 0.54 4.73 0.39 5.93e-6 Iris color (b* coordinate); TGCT cis rs10504229 0.775 rs17805074 chr8:58161048 C/T cg11062466 chr8:58055876 NA -0.36 -4.6 -0.38 1.04e-5 Developmental language disorder (linguistic errors); TGCT cis rs911555 1.000 rs911555 chr14:103999347 G/C cg12935359 chr14:103987150 CKB 0.35 4.99 0.41 2.03e-6 Intelligence (multi-trait analysis); TGCT cis rs17387100 0.515 rs2677791 chr4:16024136 G/A cg13480465 chr4:16795757 LDB2 -0.39 -5.11 -0.42 1.2e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs68170813 0.559 rs4515482 chr7:107072681 A/C cg02696742 chr7:106810147 HBP1 -0.71 -5.9 -0.47 3.17e-8 Coronary artery disease; TGCT cis rs240764 0.548 rs12206838 chr6:101180128 G/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs137699 0.652 rs2413589 chr22:39755689 C/T cg05872129 chr22:39784769 NA 0.54 4.5 0.37 1.54e-5 IgG glycosylation; TGCT cis rs6921919 0.609 rs9461455 chr6:28329731 C/T cg18815343 chr6:28367644 ZSCAN12 -0.57 -5.33 -0.43 4.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10779751 0.734 rs7533211 chr1:11132965 G/C cg08854313 chr1:11322531 MTOR 0.84 8.3 0.6 1.47e-13 Body mass index; TGCT cis rs425277 0.628 rs262668 chr1:2082602 A/G cg24578937 chr1:2090814 PRKCZ 0.26 6.95 0.53 1.8e-10 Height; TGCT cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg09177884 chr7:1199841 ZFAND2A -0.52 -4.97 -0.41 2.13e-6 Longevity;Endometriosis; TGCT cis rs2288073 0.965 rs10199334 chr2:24392618 T/C cg02683114 chr2:24398427 C2orf84 -0.25 -5.61 -0.45 1.26e-7 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs1865760 0.892 rs9379806 chr6:25940958 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.66 6.2 0.49 7.8e-9 Height; TGCT cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg11890956 chr21:40555474 PSMG1 -0.73 -7.15 -0.54 6.65e-11 Menarche (age at onset); TGCT cis rs9640161 0.750 rs11764936 chr7:150025915 G/T cg17279839 chr7:150038598 RARRES2 0.43 4.48 0.37 1.69e-5 Blood protein levels;Circulating chemerin levels; TGCT trans rs77457752 0.532 rs77481510 chr9:13902347 G/A cg23609682 chr1:3070786 PRDM16 0.51 6.81 0.52 3.8e-10 Breast cancer; TGCT cis rs7829975 0.511 rs2980426 chr8:8145609 T/C cg15556689 chr8:8085844 FLJ10661 0.88 8.41 0.6 8.32e-14 Mood instability; TGCT cis rs7605378 1.000 rs769958 chr2:200695901 G/A cg17644776 chr2:200775616 C2orf69 0.28 5.33 0.43 4.51e-7 Osteoporosis; TGCT cis rs6933660 0.745 rs9322320 chr6:151751908 C/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.88 -9.67 -0.66 8.12e-17 Menarche (age at onset); TGCT cis rs6714710 0.603 rs78006955 chr2:98455510 G/C cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs28386778 0.897 rs2665823 chr17:61885917 G/A cg26338869 chr17:61819248 STRADA -0.55 -5.04 -0.41 1.6e-6 Prudent dietary pattern; TGCT cis rs9640161 0.750 rs61421252 chr7:150037972 T/C cg10018233 chr7:150070692 REPIN1 0.32 4.78 0.39 4.84e-6 Blood protein levels;Circulating chemerin levels; TGCT trans rs114540395 0.858 rs7900797 chr10:103192220 A/G cg10198749 chr1:39920707 MACF1 0.56 7.44 0.56 1.47e-11 Schizophrenia; TGCT cis rs950169 0.922 rs11630760 chr15:85113337 G/T cg11189052 chr15:85197271 WDR73 0.77 6.44 0.5 2.34e-9 Schizophrenia; TGCT cis rs793571 0.650 rs12899638 chr15:58920275 G/A cg05156742 chr15:59063176 FAM63B 0.57 5.36 0.43 3.9e-7 Schizophrenia; TGCT cis rs554111 0.963 rs601329 chr1:21044161 A/G cg08890418 chr1:21044141 KIF17 0.59 6.23 0.49 6.74e-9 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs9653442 0.593 rs10865036 chr2:100860595 A/G cg22139774 chr2:100720529 AFF3 -0.39 -6.4 -0.5 2.93e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9916302 0.706 rs903507 chr17:37726423 A/G cg03321784 chr17:37729644 NA 0.44 4.58 0.38 1.1e-5 Glomerular filtration rate (creatinine); TGCT cis rs1552244 0.554 rs6762397 chr3:10007840 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.3 -4.7 -0.39 6.82e-6 Alzheimer's disease; TGCT cis rs1372520 0.873 rs2736989 chr4:90776257 T/C cg14346243 chr4:90757452 SNCA -0.62 -5.26 -0.43 6.17e-7 Neuroticism; TGCT cis rs2243480 1.000 rs35825738 chr7:65318027 A/G cg05590025 chr7:65112418 INTS4L2 -0.77 -4.5 -0.37 1.52e-5 Diabetic kidney disease; TGCT cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg12310025 chr6:25882481 NA 0.51 5.26 0.43 6.17e-7 Blood metabolite levels; TGCT cis rs6912958 0.667 rs7746545 chr6:88090225 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.86 0.47 4e-8 Monocyte percentage of white cells; TGCT cis rs9733 0.596 rs72702585 chr1:150696427 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT trans rs11662586 0.517 rs7228070 chr18:77698967 C/T cg05926928 chr17:57297772 GDPD1 0.78 7.64 0.57 5.01e-12 Exploratory eye movement dysfunction in schizophrenia (responsive search score); TGCT cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs9650657 0.648 rs7833945 chr8:10700266 T/G cg27411982 chr8:10470053 RP1L1 -0.22 -4.58 -0.38 1.12e-5 Neuroticism; TGCT cis rs933688 1.000 rs9293568 chr5:90737845 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.94 8.08 0.59 4.83e-13 Smoking behavior; TGCT cis rs78456975 1.000 rs11898988 chr2:1560336 G/A cg01028140 chr2:1542097 TPO -0.33 -4.53 -0.38 1.37e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs6089829 0.925 rs4809270 chr20:61676709 C/A cg08045932 chr20:61659980 NA 0.5 8.72 0.62 1.54e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs6088590 0.965 rs6119534 chr20:33441257 C/T cg06115741 chr20:33292138 TP53INP2 0.64 5.22 0.42 7.36e-7 Coronary artery disease; TGCT cis rs9898058 0.660 rs9915811 chr17:47786332 G/C cg10517230 chr17:48661425 CACNA1G 0.47 4.51 0.38 1.48e-5 Milk allergy; TGCT cis rs344364 0.511 rs1742468 chr16:1950243 C/G cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs17253792 0.822 rs74824071 chr14:56095142 T/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs344364 0.511 rs2982455 chr16:1950498 T/G cg26617929 chr16:1858877 NA -0.27 -4.75 -0.39 5.6e-6 Glomerular filtration rate in chronic kidney disease; TGCT trans rs34421088 0.548 rs2618443 chr8:11384556 A/G cg15556689 chr8:8085844 FLJ10661 -0.71 -6.63 -0.51 9.32e-10 Neuroticism; TGCT cis rs9650657 0.740 rs7002282 chr8:10666993 A/G cg27411982 chr8:10470053 RP1L1 -0.22 -4.9 -0.4 2.95e-6 Neuroticism; TGCT cis rs2274459 0.500 rs10947426 chr6:33637897 A/C cg00898486 chr6:34006557 GRM4 0.32 4.92 0.4 2.65e-6 Obesity (extreme); TGCT cis rs12134245 0.719 rs61798831 chr1:91996588 C/T cg07090678 chr1:91966139 CDC7 0.35 4.75 0.39 5.58e-6 Breast cancer; TGCT cis rs2963155 0.518 rs55817235 chr5:142765733 C/T cg17617527 chr5:142782415 NR3C1 0.8 4.92 0.4 2.65e-6 Breast cancer; TGCT cis rs7523273 0.565 rs2796239 chr1:207902206 G/A cg22525895 chr1:207977042 MIR29B2 -0.33 -5.31 -0.43 4.87e-7 Schizophrenia; TGCT cis rs2463822 0.858 rs2463836 chr11:62126494 A/G cg06239285 chr11:62104954 ASRGL1 0.92 6.76 0.52 4.71e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs950169 0.922 rs4586394 chr15:84822385 G/A cg17173187 chr15:85201210 NMB -0.56 -5.74 -0.46 6.84e-8 Schizophrenia; TGCT cis rs28595532 0.920 rs115982145 chr4:119605707 A/G cg11846333 chr4:119757529 SEC24D 0.95 4.68 0.39 7.54e-6 Cannabis dependence symptom count; TGCT cis rs17102423 0.593 rs11624558 chr14:65615653 T/C cg11161011 chr14:65562177 MAX -0.46 -5.83 -0.46 4.56e-8 Obesity-related traits; TGCT cis rs2688608 0.592 rs12253429 chr10:75496161 C/G cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs9311474 0.713 rs352166 chr3:52238677 C/T cg10802521 chr3:52805072 NEK4 -0.61 -6.98 -0.53 1.59e-10 Electroencephalogram traits; TGCT cis rs4851254 0.618 rs35730185 chr2:100648085 G/A cg07810366 chr2:100720526 AFF3 -0.46 -4.64 -0.38 8.78e-6 Intelligence (multi-trait analysis); TGCT cis rs10875746 0.903 rs11168386 chr12:48467977 C/T cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs2749592 0.918 rs11011388 chr10:38155210 C/T cg25427524 chr10:38739819 LOC399744 0.35 5.18 0.42 8.84e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9291683 0.588 rs12506364 chr4:10023448 C/T cg11266682 chr4:10021025 SLC2A9 0.68 9.96 0.67 1.58e-17 Bone mineral density; TGCT cis rs2180341 0.618 rs12199451 chr6:127597780 C/G cg24812749 chr6:127587940 RNF146 0.64 5.46 0.44 2.52e-7 Breast cancer; TGCT trans rs1496653 0.602 rs13065646 chr3:23556657 G/T cg02770683 chr12:57597238 LRP1 0.36 6.66 0.51 8.06e-10 Type 2 diabetes; TGCT cis rs9486719 0.741 rs976356 chr6:96849437 T/A cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs7267979 0.966 rs2145126 chr20:25263648 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6964587 1.000 rs2188155 chr7:91599825 A/C cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs6500602 0.527 rs13338333 chr16:4443250 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.38 5.52 0.44 1.88e-7 Schizophrenia; TGCT cis rs875971 0.505 rs1723275 chr7:65504633 G/C cg18876405 chr7:65276391 NA -0.36 -5.69 -0.45 8.79e-8 Aortic root size; TGCT trans rs1814175 0.511 rs61905634 chr11:49819736 G/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs13256369 0.760 rs7816171 chr8:8575835 T/C cg18904891 chr8:8559673 CLDN23 0.64 5.89 0.47 3.36e-8 Obesity-related traits; TGCT cis rs9929218 1.000 rs17772363 chr16:68788909 G/T cg01251360 chr16:68772225 CDH1 0.29 4.89 0.4 3.01e-6 Colorectal cancer; TGCT cis rs9379774 0.623 rs1876372 chr6:25442464 C/T cg13320114 chr6:26216906 HIST1H2AE;HIST1H2BG 0.75 4.72 0.39 6.18e-6 Coronary artery disease; TGCT cis rs9926296 0.632 rs1800286 chr16:89869761 T/C cg21285383 chr16:89894308 SPIRE2 0.34 4.52 0.38 1.43e-5 Vitiligo; TGCT cis rs12134245 0.776 rs12124682 chr1:91995542 A/G cg25838465 chr1:92012736 NA -0.41 -6.57 -0.51 1.23e-9 Breast cancer; TGCT cis rs2836950 0.520 rs2836966 chr21:40637521 A/G cg17971929 chr21:40555470 PSMG1 -0.54 -4.83 -0.4 4e-6 Menarche (age at onset); TGCT cis rs564309 0.681 rs1150917 chr1:228607395 T/C cg22700015 chr1:228743131 NA -0.75 -4.5 -0.37 1.55e-5 Hip circumference (psychosocial stress interaction); TGCT cis rs9311474 0.713 rs352169 chr3:52236762 C/T cg10802521 chr3:52805072 NEK4 -0.58 -6.37 -0.5 3.43e-9 Electroencephalogram traits; TGCT cis rs11190604 0.767 rs7085426 chr10:102163640 T/C cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9457247 0.967 rs2149092 chr6:167372978 C/T cg23791538 chr6:167370224 RNASET2 0.51 5.13 0.42 1.11e-6 Crohn's disease; TGCT cis rs7226408 0.857 rs72887063 chr18:34493121 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT trans rs2727020 0.615 rs35423199 chr11:49514914 T/C cg15704280 chr7:45808275 SEPT13 -0.75 -8.81 -0.62 9.51e-15 Coronary artery disease; TGCT cis rs2637266 0.934 rs2395408 chr10:78380929 G/A cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs55882075 0.750 rs13184690 chr5:179146993 T/C cg14593053 chr5:179126677 CANX 0.48 5.4 0.44 3.23e-7 Monocyte percentage of white cells; TGCT cis rs4862750 0.794 rs7672272 chr4:187896774 T/G cg10295955 chr4:187884368 NA -1.02 -15.6 -0.81 5.02e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.572 rs58862481 chr3:10164308 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.43 -5.07 -0.41 1.42e-6 Alzheimer's disease; TGCT cis rs17711722 0.653 rs2460421 chr7:65491123 A/T cg00343986 chr7:65444356 GUSB -0.21 -4.83 -0.4 3.87e-6 Calcium levels; TGCT cis rs7027203 0.576 rs11792101 chr9:96535470 C/T cg13679303 chr9:96623674 NA 0.53 7.67 0.57 4.34e-12 DNA methylation (variation); TGCT cis rs7714584 1.000 rs11167519 chr5:150265407 C/T cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs2836974 0.674 rs1011413 chr21:40638241 A/G cg11890956 chr21:40555474 PSMG1 -0.76 -7.44 -0.56 1.48e-11 Cognitive function; TGCT cis rs9467711 0.606 rs72841536 chr6:26378288 T/A cg10795676 chr6:26370623 BTN3A2 -0.47 -4.77 -0.39 5.18e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs3096299 0.754 rs2965816 chr16:89514183 G/T cg06640241 chr16:89574553 SPG7 -0.79 -9.08 -0.63 2.09e-15 Multiple myeloma (IgH translocation); TGCT cis rs7909074 0.831 rs2065466 chr10:45384047 T/C cg04218760 chr10:45406644 TMEM72 -0.29 -5.63 -0.45 1.15e-7 Mean corpuscular volume; TGCT cis rs9611519 0.589 rs8138917 chr22:41412425 T/C cg06634786 chr22:41940651 POLR3H -0.53 -4.84 -0.4 3.83e-6 Neuroticism; TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg01802117 chr1:53393560 SCP2 -0.46 -5.43 -0.44 2.84e-7 Monocyte count; TGCT cis rs9467711 1.000 rs9467701 chr6:26312170 G/C cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs17331151 0.505 rs71299613 chr3:52698805 G/A cg07884673 chr3:53033167 SFMBT1 0.75 5.59 0.45 1.35e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4808199 0.649 rs34755166 chr19:19665581 G/A cg03709012 chr19:19516395 GATAD2A 0.9 5.63 0.45 1.12e-7 Nonalcoholic fatty liver disease; TGCT trans rs10203711 1.000 rs907107 chr2:239565780 T/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.64 -0.51 8.76e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs2404602 0.716 rs8039545 chr15:76707247 A/G cg26408565 chr15:76604113 ETFA -0.42 -5.43 -0.44 2.8e-7 Blood metabolite levels; TGCT cis rs7267979 1.000 rs4815426 chr20:25405186 A/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4808199 0.894 rs10418051 chr19:19397789 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.81 0.46 4.95e-8 Nonalcoholic fatty liver disease; TGCT cis rs7681440 0.933 rs10005233 chr4:90743331 C/T cg26578617 chr4:90757533 SNCA -0.47 -4.83 -0.4 3.91e-6 Dementia with Lewy bodies; TGCT cis rs6598955 0.515 rs61776655 chr1:26541430 T/C cg04990556 chr1:26633338 UBXN11 -0.89 -11.3 -0.71 8.55e-21 Obesity-related traits; TGCT cis rs6121246 0.559 rs6060944 chr20:30372114 G/A cg13852791 chr20:30311386 BCL2L1 0.82 7.92 0.58 1.16e-12 Mean corpuscular hemoglobin; TGCT cis rs35934224 0.724 rs35374520 chr22:19851149 A/G cg11182965 chr22:19864308 TXNRD2 -0.36 -4.95 -0.41 2.33e-6 Glaucoma (primary open-angle); TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg14893161 chr1:205819251 PM20D1 -0.52 -7.5 -0.56 1.05e-11 Monocyte percentage of white cells; TGCT cis rs6693567 0.565 rs10157197 chr1:150250636 G/A cg09579323 chr1:150459698 TARS2 -0.57 -5.22 -0.42 7.27e-7 Migraine; TGCT cis rs1799949 1.000 rs12944597 chr17:41187684 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs6558530 0.626 rs6558524 chr8:1702512 T/G cg09410841 chr8:1729607 CLN8 0.72 6.49 0.5 1.87e-9 Systolic blood pressure; TGCT cis rs9653442 0.527 rs4850923 chr2:100782256 A/C cg22139774 chr2:100720529 AFF3 -0.34 -5.28 -0.43 5.56e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2204008 0.569 rs11495449 chr12:37995753 C/T cg26384229 chr12:38710491 ALG10B 0.87 7.79 0.57 2.32e-12 Bladder cancer; TGCT cis rs13082711 0.522 rs864241 chr3:27332674 T/C cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs5769765 0.954 rs910799 chr22:50278568 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.14 12.65 0.75 4.51e-24 Schizophrenia; TGCT cis rs7949030 0.596 rs11231138 chr11:62316195 C/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.18 0.64 1.21e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9300255 0.602 rs1106240 chr12:123626982 C/T cg00376283 chr12:123451042 ABCB9 0.72 4.96 0.41 2.31e-6 Neutrophil percentage of white cells; TGCT cis rs2229238 0.866 rs61403567 chr1:154504927 T/C cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs9611565 0.877 rs3817999 chr22:41747717 A/G cg06481639 chr22:41940642 POLR3H 0.63 5.61 0.45 1.25e-7 Vitiligo; TGCT cis rs11167764 1.000 rs7730511 chr5:141480418 T/C cg02659431 chr5:141694439 SPRY4 -0.22 -4.71 -0.39 6.46e-6 Crohn's disease; TGCT cis rs71636778 0.509 rs17340509 chr1:27274700 A/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs35146811 0.555 rs2527898 chr7:99534030 C/G cg13334819 chr7:99746414 C7orf59 -0.6 -5.05 -0.41 1.52e-6 Coronary artery disease; TGCT cis rs8141529 0.632 rs5762803 chr22:29193638 G/C cg02153584 chr22:29168773 CCDC117 0.76 6.36 0.5 3.56e-9 Lymphocyte counts; TGCT cis rs4746818 1.000 rs7071904 chr10:70903005 C/T cg11621586 chr10:70884670 VPS26A 1.22 10.78 0.7 1.56e-19 Left atrial antero-posterior diameter; TGCT cis rs1949733 0.656 rs6845969 chr4:8402465 A/T cg13073564 chr4:8508604 NA -0.47 -5.32 -0.43 4.59e-7 Response to antineoplastic agents; TGCT cis rs12458462 0.892 rs2242175 chr18:77464406 G/A cg11879182 chr18:77439856 CTDP1 0.69 8.12 0.59 3.98e-13 Monocyte count; TGCT cis rs4664308 1.000 rs17831161 chr2:160909360 A/G cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs651907 0.557 rs62284198 chr3:101474699 G/A cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.69 -0.51 7.01e-10 Colorectal cancer; TGCT cis rs3008870 1.000 rs2755248 chr1:67492624 A/G cg03991309 chr1:68237761 GNG12 0.27 4.5 0.37 1.56e-5 Lymphocyte percentage of white cells; TGCT cis rs2072499 0.722 rs61462713 chr1:156161682 C/T cg24450063 chr1:156163899 SLC25A44 1.11 10.16 0.67 5.03e-18 Testicular germ cell tumor; TGCT cis rs9457247 0.935 rs9348211 chr6:167375173 G/C cg25258033 chr6:167368657 RNASET2 -0.2 -4.82 -0.4 4.19e-6 Crohn's disease; TGCT cis rs12510870 0.599 rs34859660 chr4:74452233 A/C cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs6088590 1.000 rs55753039 chr20:33394940 C/T cg24642439 chr20:33292090 TP53INP2 0.68 6.12 0.48 1.11e-8 Coronary artery disease; TGCT cis rs12477438 0.520 rs7604557 chr2:99747829 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.47 0.86 2.08e-37 Chronic sinus infection; TGCT cis rs10504229 0.953 rs2270610 chr8:58194669 A/G cg22535103 chr8:58192502 C8orf71 -0.4 -4.71 -0.39 6.62e-6 Developmental language disorder (linguistic errors); TGCT cis rs5757676 1.000 rs5757676 chr22:39841700 T/C cg01416388 chr22:39784598 NA -0.7 -5.62 -0.45 1.21e-7 IgG glycosylation; TGCT cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg03452623 chr4:187889614 NA -0.34 -4.94 -0.41 2.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7714584 1.000 rs6579806 chr5:150271084 C/T cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg11494091 chr17:61959527 GH2 0.61 14.63 0.8 8.78e-29 Prudent dietary pattern; TGCT cis rs9467773 1.000 rs2255070 chr6:26501777 C/G cg15659132 chr6:26577336 NA 0.84 11.72 0.73 8.07e-22 Intelligence (multi-trait analysis); TGCT cis rs422249 0.512 rs174578 chr11:61605499 T/A cg01500311 chr11:61656094 FADS3 -0.33 -5.69 -0.46 8.6e-8 Trans fatty acid levels; TGCT cis rs111803315 1.000 rs112555934 chr14:59977232 T/C cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs36405 1.000 rs36412 chr14:72356535 A/G cg10066683 chr14:71515513 PCNX 0.24 4.45 0.37 1.87e-5 Yang-deficiency constitution; TGCT cis rs2204008 0.840 rs3892363 chr12:38479487 G/A cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Bladder cancer; TGCT cis rs6484504 0.576 rs58702363 chr11:31246397 C/A cg26647111 chr11:31128758 NA -0.34 -4.73 -0.39 5.88e-6 Red blood cell count; TGCT cis rs4273100 0.850 rs11204306 chr17:19267371 A/G cg01534423 chr17:18965556 NA 0.94 6.42 0.5 2.66e-9 Schizophrenia; TGCT cis rs853679 0.517 rs9380061 chr6:28132803 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs59197085 0.636 rs60324735 chr7:128465450 A/G cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs17221829 0.733 rs11018679 chr11:89362869 G/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.67 -0.39 7.58e-6 Anxiety in major depressive disorder; TGCT cis rs35883536 1.000 rs11583008 chr1:101085094 A/G cg06223162 chr1:101003688 GPR88 0.31 4.89 0.4 3.07e-6 Monocyte count; TGCT cis rs4566357 0.964 rs4296416 chr2:227921926 C/T cg11843606 chr2:227700838 RHBDD1 -0.59 -5.37 -0.43 3.8e-7 Coronary artery disease; TGCT cis rs11098499 0.954 rs7656252 chr4:120404268 T/C cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs644799 0.601 rs7902 chr11:95565288 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.62 5.6 0.45 1.32e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10276381 1.000 rs10260837 chr7:28181129 C/T cg23620719 chr7:28220237 JAZF1 0.99 5.75 0.46 6.58e-8 Crohn's disease; TGCT cis rs9399135 0.967 rs1014020 chr6:135334426 C/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs317689 0.819 rs317685 chr12:69715457 A/G cg11871910 chr12:69753446 YEATS4 -0.53 -4.61 -0.38 9.74e-6 Response to diuretic therapy; TGCT cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs308403 0.509 rs13122636 chr4:123671045 A/G cg10495464 chr4:123653540 BBS12;LOC729338 0.85 12.28 0.74 3.54e-23 Blood protein levels; TGCT cis rs7586879 0.861 rs10164466 chr2:25114069 T/C cg01884057 chr2:25150051 NA 0.27 4.81 0.4 4.36e-6 Body mass index; TGCT cis rs6733011 0.628 rs4850888 chr2:99456946 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.46 -4.63 -0.38 9.16e-6 Bipolar disorder; TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg07167872 chr1:205819463 PM20D1 0.58 7.5 0.56 1.09e-11 Menarche (age at onset); TGCT cis rs1994135 0.715 rs10844625 chr12:33693006 C/T cg06521331 chr12:34319734 NA -0.3 -4.69 -0.39 6.97e-6 Resting heart rate; TGCT cis rs7582180 0.739 rs10195793 chr2:100925803 A/G cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs10479542 0.929 rs7718673 chr5:178980009 C/T cg21226059 chr5:178986404 RUFY1 -0.44 -4.62 -0.38 9.37e-6 Lung cancer; TGCT cis rs10510102 0.808 rs17102804 chr10:123727880 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs6504340 0.600 rs2325946 chr17:46584631 G/C cg25032089 chr17:46643351 HOXB3 -0.52 -5.82 -0.46 4.61e-8 Primary tooth development (number of teeth); TGCT cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8017423 0.967 rs55962513 chr14:90729460 C/G cg04374321 chr14:90722782 PSMC1 0.78 7.86 0.58 1.59e-12 Mortality in heart failure; TGCT cis rs1005277 0.505 rs7069702 chr10:38247359 G/T cg13531842 chr10:38383804 ZNF37A 0.39 4.58 0.38 1.12e-5 Extrinsic epigenetic age acceleration; TGCT cis rs10751667 1.000 rs7394449 chr11:962190 T/C cg06064525 chr11:970664 AP2A2 -0.33 -6.53 -0.51 1.54e-9 Alzheimer's disease (late onset); TGCT cis rs7772486 0.790 rs2814880 chr6:146208937 T/G cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6061231 0.793 rs2427320 chr20:60976723 A/G cg24112000 chr20:60950667 NA -0.39 -5.06 -0.41 1.48e-6 Colorectal cancer; TGCT cis rs881375 1.000 rs1953126 chr9:123640500 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.56 0.38 1.19e-5 Rheumatoid arthritis; TGCT cis rs1552244 1.000 rs9845756 chr3:10067548 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs7412746 0.611 rs4319334 chr1:150766822 G/A cg09365446 chr1:150670422 GOLPH3L 0.32 4.6 0.38 1.04e-5 Melanoma; TGCT cis rs8056742 0.642 rs66677993 chr16:85048238 C/G cg00229868 chr16:85520891 NA 0.41 4.89 0.4 3.09e-6 Amyotrophic lateral sclerosis; TGCT cis rs45430 1.000 rs416981 chr21:42745414 G/A cg22778903 chr21:42741698 MX2 0.32 5.21 0.42 7.61e-7 Melanoma; TGCT cis rs6815814 0.731 rs10776482 chr4:38774785 A/G cg02016764 chr4:38805732 TLR1 -0.28 -4.79 -0.4 4.63e-6 Breast cancer; TGCT cis rs7614311 0.731 rs73117087 chr3:63948696 A/G cg22134162 chr3:63841271 THOC7 -0.46 -5.87 -0.47 3.73e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs11671005 0.735 rs11667591 chr19:58937637 G/A cg13877915 chr19:58951672 ZNF132 0.63 4.97 0.41 2.14e-6 Mean platelet volume; TGCT cis rs11249608 0.548 rs11960161 chr5:178453837 A/G cg21905437 chr5:178450457 ZNF879 0.43 4.5 0.37 1.53e-5 Pubertal anthropometrics; TGCT cis rs7927592 0.513 rs630225 chr11:68194611 A/C cg16797656 chr11:68205561 LRP5 0.28 5.08 0.41 1.36e-6 Total body bone mineral density; TGCT cis rs1862618 0.641 rs2591954 chr5:56245044 G/C cg24531977 chr5:56204891 C5orf35 0.69 7.29 0.55 3.25e-11 Initial pursuit acceleration; TGCT cis rs7172809 0.599 rs17471431 chr15:77749068 T/C cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs9914988 1.000 rs901975 chr17:27189774 A/G cg20469991 chr17:27169893 C17orf63 0.69 5.06 0.41 1.5e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1475911 0.744 rs12481958 chr21:43517269 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 0.45 6.35 0.5 3.68e-9 IgG glycosylation; TGCT cis rs2070488 0.965 rs6599209 chr3:38558197 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT cis rs10256972 0.621 rs2280725 chr7:1087426 G/T cg09177884 chr7:1199841 ZFAND2A -0.5 -4.68 -0.39 7.46e-6 Longevity;Endometriosis; TGCT cis rs2562456 0.874 rs2562408 chr19:21709881 C/G cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs7937612 0.965 rs10892570 chr11:120274501 G/T cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.56 -0.38 1.2e-5 Intraocular pressure; TGCT trans rs62103177 0.810 rs62103187 chr18:77627633 G/C cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs7666738 0.888 rs13110683 chr4:98983368 G/C cg05340658 chr4:99064831 C4orf37 0.49 4.88 0.4 3.14e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9814567 0.806 rs4535271 chr3:134321669 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4689388 0.750 rs10755148 chr4:6295064 A/G cg25554036 chr4:6271136 WFS1 0.51 6.79 0.52 4.21e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2456568 0.835 rs8181533 chr11:93638614 C/T cg17595323 chr11:93583763 C11orf90 -0.47 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9549260 0.785 rs10507484 chr13:41218134 T/C cg21288729 chr13:41239152 FOXO1 0.99 10.35 0.68 1.79e-18 Red blood cell count; TGCT cis rs6061231 0.631 rs927133 chr20:60972109 C/T cg15674680 chr20:60982522 CABLES2 0.57 4.91 0.4 2.81e-6 Colorectal cancer; TGCT cis rs17221829 0.703 rs12365715 chr11:89374075 G/T cg02982614 chr11:89391479 FOLH1B -0.27 -4.85 -0.4 3.63e-6 Anxiety in major depressive disorder; TGCT cis rs2456568 0.548 rs6483281 chr11:93661840 G/C cg17595323 chr11:93583763 C11orf90 -0.42 -5.26 -0.43 6.25e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs514406 0.825 rs6588441 chr1:53223494 G/A cg01802117 chr1:53393560 SCP2 0.43 5.13 0.42 1.1e-6 Monocyte count; TGCT trans rs4332037 0.539 rs55993248 chr7:2071132 A/G cg10840412 chr1:235813424 GNG4 0.95 6.94 0.53 1.97e-10 Bipolar disorder; TGCT cis rs1511802 0.666 rs13106826 chr4:187125168 T/A cg19358738 chr4:186734530 SORBS2 0.18 4.57 0.38 1.18e-5 Blood protein levels; TGCT trans rs10504390 0.656 rs78912269 chr8:66511446 C/T cg15922513 chr12:131561251 GPR133 -0.69 -6.97 -0.53 1.66e-10 IgG glycosylation; TGCT cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg05738196 chr6:26577821 NA 0.88 11.31 0.71 8.33e-21 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.967 rs7167613 chr15:77041192 C/A cg26408565 chr15:76604113 ETFA -0.37 -4.64 -0.38 8.88e-6 Blood metabolite levels; TGCT cis rs34421088 0.506 rs4841519 chr8:11146228 A/T cg03192020 chr8:11204681 TDH 0.51 4.51 0.38 1.46e-5 Neuroticism; TGCT cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg17971929 chr21:40555470 PSMG1 -0.7 -6.32 -0.49 4.38e-9 Cognitive function; TGCT cis rs380904 0.963 rs410836 chr8:144576849 A/G cg01134012 chr8:144635316 GSDMD 0.49 4.51 0.38 1.49e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs765787 0.505 rs12593605 chr15:45497448 T/A cg24006582 chr15:45444508 DUOX1 0.25 5.26 0.43 6.23e-7 Uric acid levels; TGCT cis rs1475911 1.000 rs55645900 chr21:43515728 G/T cg19766460 chr21:43528205 UMODL1;C21orf128 0.51 6.7 0.52 6.42e-10 IgG glycosylation; TGCT cis rs4285028 0.747 rs11928871 chr3:121483388 G/C cg01951420 chr3:121553821 IQCB1;EAF2 -1.03 -8.75 -0.62 1.26e-14 Multiple sclerosis; TGCT trans rs10825036 0.567 rs437228 chr10:55333482 T/C cg03092930 chr2:132586330 NA 0.53 7.07 0.54 9.91e-11 Disease-free survival in breast cancer; TGCT cis rs7223966 1.000 rs6504167 chr17:61693194 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.81 0.4 4.22e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs4499344 0.556 rs259236 chr19:33116122 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.8 7.9 0.58 1.26e-12 Mean platelet volume; TGCT cis rs10037055 1.000 rs10037055 chr5:176691279 G/T cg18465082 chr5:176734745 MXD3 0.27 4.43 0.37 2.01e-5 Migraine without aura; TGCT cis rs12478296 0.901 rs7420176 chr2:243005277 G/A cg06360820 chr2:242988706 NA -0.6 -4.96 -0.41 2.23e-6 Obesity-related traits; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg04234412 chr22:24373322 LOC391322 -0.9 -10.44 -0.68 1.07e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7552404 0.731 rs11161857 chr1:76370228 G/C cg10523679 chr1:76189770 ACADM 0.83 7.23 0.54 4.29e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs611744 0.870 rs2212703 chr8:109198401 G/C cg21045802 chr8:109455806 TTC35 0.68 6.03 0.48 1.72e-8 Dupuytren's disease; TGCT cis rs9549367 0.789 rs34568744 chr13:113894564 G/T cg18105134 chr13:113819100 PROZ -0.34 -5.52 -0.44 1.9e-7 Platelet distribution width; TGCT cis rs11190604 1.000 rs3793772 chr10:102222825 A/G cg23241863 chr10:102295624 HIF1AN 0.61 4.71 0.39 6.59e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs523522 0.962 rs4766969 chr12:120988238 A/G cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs7824557 0.564 rs4631424 chr8:11236809 T/C cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs853679 0.517 rs4713137 chr6:28083521 C/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs28386778 0.830 rs2665841 chr17:61861219 A/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs7149242 1.000 rs7149242 chr14:101159416 G/T cg18089426 chr14:101175970 NA 0.45 4.81 0.4 4.3e-6 Platelet count; TGCT cis rs12142240 0.698 rs67487250 chr1:46811333 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs2439831 0.850 rs28504496 chr15:44016883 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.88 5.93 0.47 2.85e-8 Lung cancer in ever smokers; TGCT cis rs4654899 0.680 rs12407731 chr1:21254789 C/T cg01072550 chr1:21505969 NA -0.52 -8.56 -0.61 3.7e-14 Superior frontal gyrus grey matter volume; TGCT cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg13397359 chr6:42928475 GNMT 0.73 6.8 0.52 3.86e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1799899 0.826 rs6796795 chr3:133466222 A/G cg18342939 chr3:134203408 ANAPC13;CEP63 0.48 4.91 0.4 2.85e-6 Alcohol consumption (transferrin glycosylation); TGCT cis rs7666738 0.546 rs13149516 chr4:98913030 T/A cg05340658 chr4:99064831 C4orf37 0.59 6.52 0.51 1.62e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.897 rs13339986 chr21:40605982 T/C cg17971929 chr21:40555470 PSMG1 0.93 8.72 0.62 1.49e-14 Cognitive function; TGCT cis rs12541595 0.686 rs34011925 chr8:125901855 T/C cg01919908 chr8:126310179 NSMCE2 -0.18 -4.51 -0.38 1.5e-5 Left ventricle diastolic internal dimension; TGCT cis rs9902453 0.740 rs2628189 chr17:28088813 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.83 -8.18 -0.59 2.86e-13 Coffee consumption (cups per day); TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg20007245 chr22:24372913 LOC391322 -0.71 -6.96 -0.53 1.71e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6461049 0.766 rs10256077 chr7:2171450 C/T cg22963979 chr7:1858916 MAD1L1 0.45 7.65 0.57 4.92e-12 Schizophrenia; TGCT cis rs6879260 0.963 rs1035412 chr5:179729328 C/T cg02891314 chr5:179741120 GFPT2 -0.41 -7.09 -0.54 8.81e-11 Height; TGCT cis rs1008375 1.000 rs7436403 chr4:17692685 T/G cg18681998 chr4:17616180 MED28 -0.79 -7.33 -0.55 2.58e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4689388 0.890 rs4501291 chr4:6298582 C/T cg00701064 chr4:6280414 WFS1 0.44 5.77 0.46 5.96e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6684514 0.961 rs10908497 chr1:156274740 G/A cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7296418 0.630 rs11608305 chr12:123791165 C/G cg00376283 chr12:123451042 ABCB9 0.65 5.53 0.44 1.79e-7 Platelet count; TGCT cis rs7811142 1.000 rs76913697 chr7:100002772 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs2228479 0.850 rs62052212 chr16:89981960 G/A cg06558623 chr16:89946397 TCF25 0.58 6.67 0.51 7.45e-10 Skin colour saturation; TGCT cis rs7246657 0.722 rs1975937 chr19:38091932 A/T cg03611452 chr19:38183253 ZNF781 0.59 4.72 0.39 6.14e-6 Coronary artery calcification; TGCT cis rs7772486 0.754 rs697054 chr6:146003770 C/T cg23711669 chr6:146136114 FBXO30 0.91 10.55 0.69 5.67e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs34779708 0.966 rs12769484 chr10:35465746 G/A cg03585969 chr10:35415529 CREM 0.43 4.52 0.38 1.4e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs9913156 0.707 rs9902000 chr17:4582426 A/C cg23387401 chr17:4582204 PELP1 -0.3 -4.55 -0.38 1.25e-5 Lymphocyte counts; TGCT cis rs13118159 0.641 rs4974598 chr4:1313220 C/T cg05025164 chr4:1340916 KIAA1530 0.55 4.76 0.39 5.33e-6 Longevity; TGCT trans rs1005277 0.579 rs2474580 chr10:38398713 G/A cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg17554472 chr22:41940697 POLR3H -0.46 -4.69 -0.39 7.09e-6 Vitiligo; TGCT cis rs9309473 0.514 rs62149659 chr2:73585196 C/T cg07208825 chr2:73871855 ALMS1P 0.27 5.11 0.42 1.21e-6 Metabolite levels; TGCT cis rs274567 0.501 rs272856 chr5:131687081 G/C cg24060327 chr5:131705240 SLC22A5 -0.75 -8.27 -0.6 1.8e-13 Blood metabolite levels; TGCT cis rs1514658 0.903 rs7674055 chr4:119272958 T/C cg21605333 chr4:119757512 SEC24D -0.5 -4.5 -0.37 1.56e-5 Congenital heart disease (maternal effect); TGCT cis rs7926906 1.000 rs7944479 chr11:90524289 T/C cg26138821 chr11:89956704 CHORDC1 -0.51 -5.52 -0.44 1.92e-7 Intelligence (multi-trait analysis); TGCT cis rs10791323 0.582 rs2851120 chr11:133708065 A/G cg15485101 chr11:133734466 NA 0.38 5.0 0.41 1.95e-6 Childhood ear infection; TGCT cis rs7618915 1.000 rs3844291 chr3:52341215 A/C cg10802521 chr3:52805072 NEK4 -0.57 -5.92 -0.47 2.9e-8 Bipolar disorder; TGCT cis rs3785574 0.638 rs2854182 chr17:61969062 G/A cg11494091 chr17:61959527 GH2 0.42 6.96 0.53 1.76e-10 Height; TGCT cis rs3784262 0.669 rs12915508 chr15:58302036 G/A cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.27 -0.49 5.58e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6598955 0.640 rs6667826 chr1:26531408 T/C cg04990556 chr1:26633338 UBXN11 -0.89 -11.04 -0.7 3.67e-20 Obesity-related traits; TGCT cis rs6087990 0.735 rs2424921 chr20:31385814 C/T cg13636640 chr20:31349939 DNMT3B 0.97 12.49 0.75 1.08e-23 Ulcerative colitis; TGCT cis rs727563 0.635 rs713988 chr22:42159072 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.69 0.39 7.09e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1878931 0.624 rs27241 chr16:3447282 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.45 -0.5 2.3e-9 Body mass index (adult); TGCT cis rs9653442 0.675 rs2871326 chr2:100662010 T/C cg07810366 chr2:100720526 AFF3 -0.42 -7.07 -0.54 9.86e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs651907 0.557 rs11712748 chr3:101383562 G/A cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.08 -0.54 9.37e-11 Colorectal cancer; TGCT cis rs3733585 0.699 rs7683283 chr4:9969974 T/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.85 -0.58 1.63e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2282300 0.956 rs654710 chr11:30394303 A/G cg25418670 chr11:30344373 C11orf46 0.4 5.13 0.42 1.08e-6 Morning vs. evening chronotype; TGCT cis rs13242816 1.000 rs1018859 chr7:116067347 C/T cg16553024 chr7:116138462 CAV2 -0.48 -5.31 -0.43 4.89e-7 P wave duration; TGCT trans rs1005277 0.579 rs1780145 chr10:38537070 A/G cg27523141 chr10:43048294 ZNF37B 0.73 8.5 0.61 5.09e-14 Extrinsic epigenetic age acceleration; TGCT cis rs4975709 0.610 rs4975704 chr5:1859807 C/A cg12288994 chr5:1860383 NA 0.24 4.52 0.38 1.42e-5 Cardiovascular disease risk factors; TGCT cis rs3617 0.625 rs7652667 chr3:52866535 C/A cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2075165 0.901 rs6701440 chr1:156249505 A/G cg20302342 chr1:156215951 PAQR6 0.36 5.38 0.44 3.56e-7 Tonsillectomy; TGCT cis rs8017423 0.935 rs11628906 chr14:90738002 C/T cg04374321 chr14:90722782 PSMC1 -0.75 -7.32 -0.55 2.67e-11 Mortality in heart failure; TGCT cis rs7824557 0.614 rs2060456 chr8:11213363 C/T cg21775007 chr8:11205619 TDH 0.68 6.46 0.5 2.16e-9 Retinal vascular caliber; TGCT cis rs8180040 0.620 rs6767907 chr3:47162661 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.49 -0.61 5.34e-14 Colorectal cancer; TGCT cis rs7027203 0.576 rs7874836 chr9:96559370 C/T cg14598338 chr9:96623480 NA -0.54 -7.8 -0.57 2.19e-12 DNA methylation (variation); TGCT cis rs60843830 0.661 rs7561648 chr2:105171 G/T cg00108164 chr2:264199 ACP1;SH3YL1 0.54 4.51 0.38 1.45e-5 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7666738 0.830 rs10005120 chr4:99038200 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2486288 0.656 rs8040185 chr15:45552081 G/A cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs72781680 0.752 rs7578606 chr2:23902360 T/C cg08917208 chr2:24149416 ATAD2B 1.0 5.56 0.45 1.59e-7 Lymphocyte counts; TGCT cis rs2535633 0.631 rs6799185 chr3:53101580 C/T cg10802521 chr3:52805072 NEK4 -0.52 -5.44 -0.44 2.77e-7 Body mass index; TGCT cis rs9325144 0.624 rs12231544 chr12:38901956 C/T cg26384229 chr12:38710491 ALG10B -0.6 -5.48 -0.44 2.31e-7 Morning vs. evening chronotype; TGCT cis rs7666738 0.830 rs2114426 chr4:98933130 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.570 rs12159188 chr22:42121125 A/T cg03806693 chr22:41940476 POLR3H 1.02 10.91 0.7 7.73e-20 Vitiligo; TGCT cis rs6951245 0.935 rs113365567 chr7:1108785 T/C cg18402987 chr7:1209562 NA 0.78 6.58 0.51 1.16e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4930561 0.714 rs6591335 chr11:67976812 T/C cg04465784 chr11:67976953 SUV420H1 -0.38 -5.5 -0.44 2.07e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs13108904 0.557 rs1250095 chr4:1239312 C/T cg20887711 chr4:1340912 KIAA1530 -0.58 -4.97 -0.41 2.17e-6 Obesity-related traits; TGCT cis rs9906944 0.707 rs12942084 chr17:47114392 A/G cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs8017423 0.967 rs17188605 chr14:90722579 C/T cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs1670533 1.000 rs11247971 chr4:1053580 A/G cg27284194 chr4:1044797 NA 0.66 5.69 0.45 8.85e-8 Recombination rate (females); TGCT cis rs9534288 0.797 rs9534287 chr13:46603926 A/C cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs1059312 1.000 rs3825180 chr12:129279242 A/G cg09035930 chr12:129282057 SLC15A4 -0.56 -11.07 -0.71 3.1e-20 Systemic lupus erythematosus; TGCT cis rs295140 0.605 rs295149 chr2:201175244 A/G cg23649088 chr2:200775458 C2orf69 -0.28 -4.52 -0.38 1.42e-5 QT interval; TGCT cis rs8051431 0.840 rs8056943 chr16:72008854 G/A cg06353428 chr16:71660113 MARVELD3 0.58 4.98 0.41 2.07e-6 LDL cholesterol levels; TGCT cis rs2153535 0.601 rs9502719 chr6:8541032 A/G cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.46e-7 Motion sickness; TGCT cis rs72781680 0.821 rs72796325 chr2:24134537 G/A cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs9831754 0.906 rs2102601 chr3:78410536 G/A cg06138941 chr3:78371609 NA -0.47 -5.01 -0.41 1.87e-6 Calcium levels; TGCT cis rs17030434 0.871 rs74380369 chr4:154730273 C/T cg14289246 chr4:154710475 SFRP2 -0.9 -7.58 -0.56 7.16e-12 Electrocardiographic conduction measures; TGCT cis rs514406 0.861 rs1749907 chr1:53259658 C/T cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs13064411 0.696 rs9869318 chr3:113146271 T/C cg18753928 chr3:113234510 CCDC52 -0.7 -5.12 -0.42 1.12e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs938554 0.513 rs3775948 chr4:9995182 G/C cg02734326 chr4:10020555 SLC2A9 0.53 4.92 0.4 2.71e-6 Blood metabolite levels; TGCT cis rs2204008 0.805 rs11514348 chr12:38243427 T/C cg13010199 chr12:38710504 ALG10B 0.64 5.01 0.41 1.85e-6 Bladder cancer; TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.27 0.81 2.85e-30 Prudent dietary pattern; TGCT cis rs7635838 0.617 rs346084 chr3:11281159 C/T cg00170343 chr3:11313890 ATG7 0.64 6.28 0.49 5.27e-9 HDL cholesterol; TGCT cis rs4711336 1.000 rs11759396 chr6:33656654 C/G cg14003231 chr6:33640908 ITPR3 0.28 4.49 0.37 1.58e-5 Height; TGCT cis rs981844 0.740 rs1020702 chr4:154685712 A/C cg14289246 chr4:154710475 SFRP2 -0.91 -8.31 -0.6 1.38e-13 Response to statins (LDL cholesterol change); TGCT cis rs778371 0.915 rs748002 chr2:233757679 G/A cg08000102 chr2:233561755 GIGYF2 -0.6 -6.31 -0.49 4.46e-9 Schizophrenia; TGCT cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg18765753 chr7:1198926 ZFAND2A -0.4 -4.45 -0.37 1.85e-5 Longevity;Endometriosis; TGCT cis rs514406 0.505 rs6703127 chr1:53180565 C/T cg24675658 chr1:53192096 ZYG11B -0.8 -9.66 -0.66 8.35e-17 Monocyte count; TGCT cis rs12477438 0.520 rs34766932 chr2:99737273 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs709400 0.633 rs7160208 chr14:103965528 G/A cg26031613 chr14:104095156 KLC1 0.84 9.5 0.65 2.08e-16 Body mass index; TGCT cis rs7647973 0.580 rs35218722 chr3:49275805 A/G cg02487422 chr3:49467188 NICN1 0.55 5.32 0.43 4.77e-7 Menarche (age at onset); TGCT cis rs68170813 0.559 rs78440378 chr7:106962782 C/A cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs362296 0.671 rs1006798 chr4:3258373 A/G cg06533319 chr4:3265114 C4orf44 0.24 4.52 0.38 1.44e-5 Parental longevity (mother's age at death); TGCT cis rs2742417 0.609 rs11709306 chr3:45773732 G/A cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs10466239 0.730 rs12221341 chr10:43857330 C/G cg12891252 chr10:43902500 HNRNPF -0.74 -4.95 -0.41 2.4e-6 Telomere length; TGCT cis rs1971762 0.527 rs1247957 chr12:53961493 G/T cg16917193 chr12:54089295 NA -1.04 -10.73 -0.69 2.06e-19 Height; TGCT cis rs2242116 0.796 rs2290546 chr3:46965197 C/G cg02527881 chr3:46936655 PTH1R -0.33 -6.09 -0.48 1.29e-8 Birth weight; TGCT trans rs10802346 0.524 rs10802356 chr1:246385857 T/C cg13514129 chr1:39547527 MACF1 0.96 8.52 0.61 4.45e-14 Fractional exhaled nitric oxide (childhood); TGCT cis rs9359856 0.510 rs17294495 chr6:90445753 T/G cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.66 -0.39 7.9e-6 Bipolar disorder; TGCT cis rs9527 0.571 rs12765337 chr10:104635344 G/C cg04362960 chr10:104952993 NT5C2 0.56 4.77 0.39 5.06e-6 Arsenic metabolism; TGCT trans rs6931743 1 rs6931743 chr6:19236109 G/A cg05334032 chr14:105041531 NA 0.66 6.74 0.52 5.38e-10 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs295140 0.502 rs3754797 chr2:201242293 G/A cg04283868 chr2:201171347 SPATS2L 0.52 4.98 0.41 2.06e-6 QT interval; TGCT cis rs6684514 1.000 rs12141236 chr1:156302575 A/C cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6754311 0.731 rs309164 chr2:136691825 T/C cg07169764 chr2:136633963 MCM6 0.69 6.43 0.5 2.49e-9 Mosquito bite size; TGCT trans rs56011263 0.687 rs11734460 chr4:705074 C/T cg12575136 chr18:32820987 ZNF397 0.77 9.37 0.64 4.3e-16 White blood cell count; TGCT cis rs1538970 0.962 rs4660301 chr1:45820149 T/A cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs2982552 0.873 rs2152751 chr6:152069999 A/G cg22157087 chr6:152012887 ESR1 0.2 4.77 0.39 5e-6 Bone properties (heel); TGCT cis rs4727027 0.680 rs6464941 chr7:148826352 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.58 5.17 0.42 9.03e-7 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7044106 0.791 rs7036766 chr9:123479621 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 6.99 0.53 1.48e-10 Hip circumference adjusted for BMI; TGCT cis rs10504229 0.679 rs17193048 chr8:58055392 G/A cg08280861 chr8:58055591 NA 0.51 5.73 0.46 7.17e-8 Developmental language disorder (linguistic errors); TGCT cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg11003573 chr3:44754125 ZNF502 0.45 5.08 0.42 1.32e-6 Depressive symptoms; TGCT cis rs7552404 0.924 rs1303169 chr1:76195041 T/C cg22875332 chr1:76189707 ACADM 0.72 9.02 0.63 2.88e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4478858 0.735 rs10798843 chr1:31797094 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs2458413 0.542 rs2002812 chr8:105365234 C/T cg04554929 chr8:105342491 NA 0.49 5.9 0.47 3.21e-8 Paget's disease; TGCT cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs889312 0.500 rs832566 chr5:56151744 C/T cg12311346 chr5:56204834 C5orf35 -0.44 -4.67 -0.39 7.74e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs7666738 0.753 rs13122897 chr4:98936185 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1975974 1.000 rs1985718 chr17:21731656 C/T cg18423549 chr17:21743878 NA -0.58 -5.39 -0.44 3.34e-7 Psoriasis; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg10150615 chr22:24372951 LOC391322 -1.01 -13.22 -0.76 1.96e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7149242 0.696 rs7141210 chr14:101182470 T/C cg11193865 chr14:101193038 DLK1 -0.48 -5.41 -0.44 3.15e-7 Platelet count; TGCT cis rs10751667 0.666 rs7103585 chr11:971166 T/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs74233809 1.000 rs79668541 chr10:104793904 C/T cg05855489 chr10:104503620 C10orf26 0.77 4.55 0.38 1.27e-5 Birth weight; TGCT trans rs877282 0.838 rs34912955 chr10:772222 T/C cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs8177253 1.000 rs6439439 chr3:133481498 G/T cg11941060 chr3:133502564 NA -0.29 -6.15 -0.48 9.6e-9 Iron status biomarkers; TGCT cis rs6582630 0.555 rs7133706 chr12:38475465 G/A cg26384229 chr12:38710491 ALG10B -0.81 -7.57 -0.56 7.38e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9467773 0.620 rs2451731 chr6:26624822 A/C cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs3096299 1.000 rs3096299 chr16:89448663 G/A cg06640241 chr16:89574553 SPG7 0.7 7.0 0.53 1.44e-10 Multiple myeloma (IgH translocation); TGCT cis rs514406 0.861 rs503296 chr1:53283088 A/G cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs3784262 0.669 rs12914455 chr15:58312096 G/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.83e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4889911 0.544 rs2587498 chr17:77830737 G/A cg00646381 chr17:77835854 NA 0.44 6.6 0.51 1.06e-9 Electroencephalogram traits; TGCT cis rs4252435 0.614 rs78357866 chr7:142629280 T/G cg09833174 chr7:143059591 FAM131B -1.03 -4.71 -0.39 6.56e-6 Cancer; TGCT cis rs7666738 0.830 rs35276471 chr4:99068691 A/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 0.651 rs313829 chr7:65552497 A/G cg07424592 chr7:64974309 NA 0.61 5.02 0.41 1.74e-6 Aortic root size; TGCT cis rs13256369 0.755 rs12680167 chr8:8562467 A/G cg18904891 chr8:8559673 CLDN23 0.59 5.43 0.44 2.82e-7 Obesity-related traits; TGCT cis rs4919694 1.000 rs7083328 chr10:104769268 G/A cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs416603 0.967 rs7191538 chr16:11363389 C/G cg00044050 chr16:11439710 C16orf75 -0.81 -8.38 -0.6 9.95e-14 Type 1 diabetes; TGCT cis rs7091068 0.616 rs7901507 chr10:95505424 C/G cg20715218 chr10:95462985 C10orf4 0.53 4.71 0.39 6.57e-6 Urinary tract infection frequency; TGCT cis rs9346649 0.630 rs4235913 chr6:168491697 T/C cg02770688 chr6:168491649 NA 0.34 6.05 0.48 1.6e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs12497850 0.765 rs12487580 chr3:49182932 G/A cg06212747 chr3:49208901 KLHDC8B 0.61 5.55 0.45 1.66e-7 Parkinson's disease; TGCT cis rs9733 0.596 rs2867301 chr1:150653795 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs6089829 0.962 rs6011548 chr20:61666063 C/T cg08564027 chr20:61660810 NA 0.37 6.64 0.51 8.85e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs17539620 0.624 rs871068 chr6:154837514 C/A cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs7666738 0.753 rs17483788 chr4:98985623 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs4951018 0.853 rs1573104 chr1:205636907 A/C cg14159672 chr1:205819179 PM20D1 -0.39 -4.45 -0.37 1.85e-5 Prostate-specific antigen levels; TGCT cis rs9486719 1.000 rs2472890 chr6:96867646 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs8177253 0.665 rs7646118 chr3:133450039 C/T cg11941060 chr3:133502564 NA -0.26 -5.32 -0.43 4.74e-7 Iron status biomarkers; TGCT cis rs11792861 1.000 rs11792861 chr9:111809295 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.54 0.38 1.29e-5 Menarche (age at onset); TGCT cis rs1371867 0.846 rs959022 chr8:101295992 T/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs8002180 0.959 rs7317112 chr13:95923523 C/T cg24476569 chr13:95954382 ABCC4 -0.38 -4.71 -0.39 6.51e-6 Blood metabolite levels; TGCT cis rs12200560 0.505 rs211172 chr6:97070691 C/A cg06623918 chr6:96969491 KIAA0776 0.59 5.02 0.41 1.76e-6 Coronary heart disease; TGCT trans rs7819412 0.511 rs2409797 chr8:11433780 T/C cg06636001 chr8:8085503 FLJ10661 -0.78 -7.03 -0.53 1.25e-10 Triglycerides; TGCT cis rs57590327 0.679 rs35628094 chr3:81605371 C/A cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs2836950 0.527 rs2836958 chr21:40623526 T/C cg11890956 chr21:40555474 PSMG1 -0.69 -6.81 -0.52 3.7e-10 Menarche (age at onset); TGCT cis rs950169 0.580 rs17598114 chr15:85171317 C/T cg12863693 chr15:85201151 NMB 0.44 5.2 0.42 7.82e-7 Schizophrenia; TGCT cis rs74544699 1.000 rs79472060 chr4:74837932 G/A cg16072462 chr4:74847758 PF4 0.76 4.86 0.4 3.49e-6 Growth-regulated protein alpha levels; TGCT cis rs67478160 0.609 rs1547604 chr14:104270659 A/T cg01849466 chr14:104193079 ZFYVE21 -0.17 -4.44 -0.37 1.94e-5 Schizophrenia; TGCT cis rs904251 0.861 rs1757169 chr6:37487076 G/T cg25019722 chr6:37503610 NA -0.5 -6.92 -0.53 2.17e-10 Cognitive performance; TGCT cis rs7542091 0.704 rs4133950 chr1:210044393 C/G cg00989853 chr1:209979345 IRF6 0.43 4.58 0.38 1.12e-5 Monobrow; TGCT cis rs2066819 1.000 rs2371454 chr12:56647243 A/G cg26714650 chr12:56694279 CS 1.33 6.24 0.49 6.46e-9 Psoriasis vulgaris; TGCT cis rs35306767 0.855 rs12771179 chr10:872347 A/G cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs9467711 1.000 rs6939799 chr6:26328366 G/A cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs910316 0.967 rs11624893 chr14:75660124 A/G cg08847533 chr14:75593920 NEK9 -0.94 -9.91 -0.66 2.11e-17 Height; TGCT cis rs8014204 0.804 rs35641442 chr14:75207263 G/A cg06637938 chr14:75390232 RPS6KL1 0.74 7.31 0.55 2.81e-11 Caffeine consumption; TGCT cis rs2075371 0.933 rs2544182 chr7:133949793 C/T cg11752832 chr7:134001865 SLC35B4 0.7 6.05 0.48 1.57e-8 Mean platelet volume; TGCT cis rs916888 0.821 rs199525 chr17:44847834 T/G cg17911788 chr17:44343683 NA -0.62 -6.7 -0.52 6.65e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs1814175 0.585 rs4881661 chr11:50000117 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT trans rs804280 0.509 rs9886639 chr8:11784529 G/T cg15556689 chr8:8085844 FLJ10661 0.8 7.54 0.56 8.53e-12 Myopia (pathological); TGCT cis rs10791323 0.569 rs10791335 chr11:133739571 A/T cg15485101 chr11:133734466 NA 0.38 5.54 0.45 1.7e-7 Childhood ear infection; TGCT cis rs9527 0.590 rs10883834 chr10:104881402 T/C cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs2013441 1.000 rs2526483 chr17:20112216 A/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs2404602 0.608 rs12439484 chr15:76602937 A/C cg22467129 chr15:76604101 ETFA -0.63 -8.12 -0.59 3.98e-13 Blood metabolite levels; TGCT cis rs710216 0.843 rs710220 chr1:43415346 G/T cg03128534 chr1:43423976 SLC2A1 0.59 4.83 0.4 3.93e-6 Red cell distribution width; TGCT cis rs13118159 0.509 rs9683830 chr4:1377873 A/G cg05025164 chr4:1340916 KIAA1530 0.79 6.64 0.51 8.6e-10 Longevity; TGCT cis rs17376456 0.825 rs34967135 chr5:93221785 G/A cg21475434 chr5:93447410 FAM172A 0.7 4.9 0.4 2.96e-6 Diabetic retinopathy; TGCT cis rs12449000 1 rs12449000 chr16:89872970 T/C cg27121462 chr16:89883253 FANCA 0.73 7.17 0.54 5.81e-11 Schizophrenia; TGCT cis rs9611565 0.580 rs5758449 chr22:42140160 C/T cg13695892 chr22:41940480 POLR3H 0.84 7.96 0.58 9.2e-13 Vitiligo; TGCT cis rs7666738 0.791 rs17549003 chr4:98969132 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs4478858 0.684 rs4949372 chr1:31738857 G/A cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs11696845 0.626 rs1111032 chr20:43378770 A/G cg25301532 chr20:43378953 KCNK15 0.47 5.15 0.42 9.92e-7 Obesity-related traits; TGCT cis rs9443645 0.901 rs9443638 chr6:79720867 T/A cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.692 rs7532149 chr1:46824932 A/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs57024841 0.562 rs2071006 chr9:139839904 G/T cg00693599 chr9:139836323 FBXW5 -0.22 -5.03 -0.41 1.68e-6 Beta-trace protein levels; TGCT cis rs9467773 1.000 rs1884946 chr6:26545308 C/G cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.11e-23 Intelligence (multi-trait analysis); TGCT cis rs9788682 1.000 rs7181245 chr15:78814389 C/T cg24631222 chr15:78858424 CHRNA5 0.89 7.68 0.57 4.22e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9468199 1.000 rs9468199 chr6:27681215 G/A cg27179866 chr6:27740120 NA 0.39 4.5 0.37 1.52e-5 Parkinson's disease; TGCT cis rs7914558 1.000 rs11191539 chr10:104819770 A/G cg15744005 chr10:104629667 AS3MT -0.38 -4.69 -0.39 7.04e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17122693 0.748 rs72681607 chr14:51115866 T/C cg04730355 chr14:51134070 SAV1 1.35 12.44 0.75 1.47e-23 Cognitive performance; TGCT cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg10047753 chr17:41438598 NA 0.95 9.5 0.65 2.09e-16 Menopause (age at onset); TGCT cis rs4727027 0.866 rs35599790 chr7:148806012 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.6 0.38 1.04e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs453301 0.658 rs9650616 chr8:8869199 T/G cg00184457 chr8:8946301 NA -0.26 -4.71 -0.39 6.41e-6 Joint mobility (Beighton score); TGCT cis rs2404602 0.583 rs12898415 chr15:76574232 C/T cg22467129 chr15:76604101 ETFA -0.61 -7.93 -0.58 1.07e-12 Blood metabolite levels; TGCT cis rs2836974 0.568 rs2142111 chr21:40549289 G/C cg11890956 chr21:40555474 PSMG1 0.8 7.51 0.56 1e-11 Cognitive function; TGCT cis rs11195062 0.521 rs4918485 chr10:111949323 A/T cg00817464 chr10:111662876 XPNPEP1 0.27 4.52 0.38 1.4e-5 Multiple myeloma; TGCT cis rs6835098 1.000 rs4561909 chr4:174086937 A/T cg08422745 chr4:174089978 GALNT7 -1.0 -10.07 -0.67 8.62e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs11030122 0.702 rs12286710 chr11:3967171 T/G cg18678763 chr11:4115507 RRM1 -0.49 -6.27 -0.49 5.56e-9 Mean platelet volume;Platelet distribution width; TGCT cis rs889312 0.532 rs6877300 chr5:56008916 C/T cg17801930 chr5:56009405 NA -0.25 -4.57 -0.38 1.18e-5 Breast cancer;Breast cancer (early onset); TGCT cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs7552404 0.960 rs12134854 chr1:76137606 A/G cg22875332 chr1:76189707 ACADM 0.8 10.09 0.67 7.7e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1205863 1.000 rs1205877 chr6:11945807 G/A cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs3733585 0.673 rs4235348 chr4:9951968 T/C cg00071950 chr4:10020882 SLC2A9 -0.55 -6.63 -0.51 9.3e-10 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs10506458 1.000 rs11174759 chr12:63444363 A/T cg22491629 chr6:157744540 C6orf35 -0.96 -8.34 -0.6 1.21e-13 Hemostatic factors and hematological phenotypes; TGCT cis rs10504229 1.000 rs17216648 chr8:58169429 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12049351 0.719 rs10916499 chr1:229641078 T/G cg12130225 chr1:229698885 NA 0.39 4.6 0.38 1.02e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7829975 0.514 rs2979139 chr8:8268313 A/G cg15556689 chr8:8085844 FLJ10661 0.71 6.27 0.49 5.47e-9 Mood instability; TGCT cis rs875971 0.862 rs4718330 chr7:65715243 G/A cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.27e-7 Aortic root size; TGCT cis rs6906287 0.647 rs12206329 chr6:118863789 G/T cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg08736216 chr1:53307985 ZYG11A -0.27 -5.37 -0.43 3.74e-7 Monocyte count; TGCT cis rs61990749 0.597 rs176971 chr14:78191599 T/G cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs10193935 0.901 rs13393459 chr2:42463124 C/T cg27598129 chr2:42591480 NA -0.39 -5.15 -0.42 9.84e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9357506 1.000 rs58585138 chr6:46302987 A/G cg21115430 chr6:46460003 NA -0.27 -5.47 -0.44 2.43e-7 Body mass index; TGCT cis rs3008870 1.000 rs2985817 chr1:67398607 G/C cg11518657 chr1:67396239 MIER1 0.54 4.68 0.39 7.24e-6 Lymphocyte percentage of white cells; TGCT cis rs2456568 0.802 rs11020586 chr11:93638547 G/A cg14065697 chr11:93583672 C11orf90 -0.38 -4.74 -0.39 5.65e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6728642 0.614 rs113485946 chr2:97866442 T/C cg26665480 chr2:98280029 ACTR1B -0.97 -4.85 -0.4 3.69e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs362272 0.524 rs6819202 chr4:3368264 G/A cg18352616 chr4:3374830 RGS12 0.24 5.04 0.41 1.6e-6 Serum sulfate level; TGCT cis rs644799 0.862 rs1150361 chr11:95633805 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.82 9.32 0.64 5.46e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4665809 0.590 rs2303892 chr2:26461733 C/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs2880765 0.835 rs56406982 chr15:86036379 G/A cg13263323 chr15:86062960 AKAP13 -0.22 -4.84 -0.4 3.84e-6 Coronary artery disease; TGCT cis rs10791323 0.582 rs2723613 chr11:133706696 G/A cg03690763 chr11:133734501 NA -0.35 -5.38 -0.44 3.5e-7 Childhood ear infection; TGCT cis rs6121246 0.954 rs6060978 chr20:30416893 G/A cg18721089 chr20:30220636 NA -0.45 -4.93 -0.4 2.56e-6 Mean corpuscular hemoglobin; TGCT cis rs12497850 0.931 rs6446253 chr3:48911443 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs9341808 0.558 rs2322635 chr6:80897210 A/G cg08355045 chr6:80787529 NA 0.31 5.01 0.41 1.81e-6 Sitting height ratio; TGCT cis rs1153858 1.000 rs4775937 chr15:45678614 C/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs3806843 0.771 rs801174 chr5:140112712 C/T cg19875535 chr5:140030758 IK -0.37 -6.19 -0.49 7.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4665809 0.887 rs2384324 chr2:26354239 A/G cg25036284 chr2:26402008 FAM59B -0.52 -4.59 -0.38 1.08e-5 Gut microbiome composition (summer); TGCT cis rs9611519 0.964 rs4820428 chr22:41537589 C/T cg13695892 chr22:41940480 POLR3H 0.51 4.57 0.38 1.16e-5 Neuroticism; TGCT cis rs6519955 0.860 rs8136098 chr22:46425646 A/G cg05468064 chr22:46423449 NA 0.54 5.62 0.45 1.21e-7 Dupuytren's disease; TGCT cis rs2013441 0.965 rs2703790 chr17:20163209 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs875971 0.660 rs28698552 chr7:66005018 A/G cg00343986 chr7:65444356 GUSB 0.24 5.29 0.43 5.43e-7 Aortic root size; TGCT cis rs2404602 0.716 rs12437627 chr15:76845050 T/C cg22467129 chr15:76604101 ETFA -0.55 -6.51 -0.5 1.65e-9 Blood metabolite levels; TGCT trans rs1557351 0.512 rs17751615 chr18:54730479 A/T cg02701435 chr19:4903909 ARRDC5 0.6 7.06 0.54 1.02e-10 Multiple sclerosis (age of onset); TGCT cis rs2832191 0.716 rs1984012 chr21:30392472 T/C cg08807101 chr21:30365312 RNF160 0.64 6.06 0.48 1.52e-8 Dental caries; TGCT cis rs7014346 0.767 rs11998706 chr8:128422098 C/G cg04263511 chr8:128962092 PVT1 -0.31 -4.5 -0.37 1.54e-5 Colorectal cancer; TGCT cis rs12142240 0.698 rs41294458 chr1:46810304 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs42648 0.596 rs194511 chr7:89846727 A/G cg25739043 chr7:89950458 NA -0.51 -4.85 -0.4 3.65e-6 Homocysteine levels; TGCT cis rs7937682 0.575 rs34695265 chr11:111719128 T/C cg09085632 chr11:111637200 PPP2R1B 0.88 8.32 0.6 1.31e-13 Primary sclerosing cholangitis; TGCT cis rs2836974 0.796 rs77153312 chr21:40695499 G/A cg11890956 chr21:40555474 PSMG1 1.12 11.39 0.72 5.25e-21 Cognitive function; TGCT cis rs6951245 0.872 rs57068908 chr7:1060084 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.54 -0.38 1.32e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs35306767 0.903 rs12762228 chr10:880854 G/A cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs6840360 1.000 rs6840360 chr4:152604031 C/T cg17479576 chr4:152424074 FAM160A1 -0.49 -5.3 -0.43 5.05e-7 Intelligence (multi-trait analysis); TGCT cis rs6460942 0.908 rs6979124 chr7:12232551 G/T cg06484146 chr7:12443880 VWDE -0.52 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs2637266 0.967 rs4553314 chr10:78358244 C/T cg18941641 chr10:78392320 NA 0.41 4.86 0.4 3.51e-6 Pulmonary function; TGCT cis rs79349575 0.749 rs8182364 chr17:47018025 A/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs6952808 0.689 rs11771625 chr7:2050401 C/T cg22963979 chr7:1858916 MAD1L1 -0.46 -7.22 -0.54 4.49e-11 Bipolar disorder and schizophrenia; TGCT cis rs910316 1.000 rs13099 chr14:75599155 G/A cg11812906 chr14:75593930 NEK9 -0.73 -7.08 -0.54 9.66e-11 Height; TGCT cis rs7119038 0.509 rs10892257 chr11:118579327 G/A cg19308663 chr11:118741387 NA 0.24 4.5 0.37 1.54e-5 Sjögren's syndrome; TGCT cis rs1218582 0.744 rs6674853 chr1:154892753 G/C cg09359103 chr1:154839909 KCNN3 -0.71 -14.71 -0.8 5.71e-29 Prostate cancer; TGCT cis rs9818758 0.607 rs34823813 chr3:49749976 G/A cg07636037 chr3:49044803 WDR6 -0.99 -4.74 -0.39 5.85e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4819852 1.000 rs1034565 chr22:19984211 A/G cg07821417 chr22:19972146 ARVCF -0.18 -4.7 -0.39 6.94e-6 Pulse pressure; TGCT cis rs10851411 0.789 rs12898937 chr15:42770853 G/A cg23803468 chr15:43513504 EPB42 -0.24 -4.75 -0.39 5.44e-6 Glucose homeostasis traits; TGCT cis rs2153535 0.601 rs330105 chr6:8543981 A/C cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.56e-7 Motion sickness; TGCT cis rs10883723 0.810 rs7912901 chr10:104277440 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs35771425 0.500 rs3738199 chr1:211545344 A/G cg26515805 chr1:211431828 RCOR3 -0.46 -5.28 -0.43 5.52e-7 Educational attainment (years of education); TGCT cis rs2404602 0.647 rs4312276 chr15:77164361 T/C cg22467129 chr15:76604101 ETFA 0.47 4.79 0.4 4.69e-6 Blood metabolite levels; TGCT cis rs2576037 0.583 rs8086286 chr18:44467515 A/G cg23302884 chr18:44338147 ST8SIA5 0.45 5.23 0.42 7.06e-7 Personality dimensions; TGCT cis rs9393777 0.720 rs35212793 chr6:26998693 T/C cg16898833 chr6:26189333 HIST1H4D 0.97 5.95 0.47 2.6e-8 Intelligence (multi-trait analysis); TGCT cis rs1008375 1.000 rs2058338 chr4:17678600 A/G cg16339924 chr4:17578868 LAP3 -0.53 -4.5 -0.37 1.56e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs56309584 0.673 rs11650444 chr17:8106317 C/T cg08322244 chr17:8066669 VAMP2 -0.55 -5.16 -0.42 9.44e-7 Initial pursuit acceleration; TGCT cis rs2688608 0.592 rs11000759 chr10:75493726 G/A cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs968567 0.539 rs174549 chr11:61571382 A/G cg01500311 chr11:61656094 FADS3 0.28 4.94 0.41 2.52e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs12477438 0.520 rs6717729 chr2:99756941 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.03 12.86 0.76 1.46e-24 Chronic sinus infection; TGCT cis rs9611565 0.592 rs5996039 chr22:41981957 A/G cg06634786 chr22:41940651 POLR3H -0.83 -7.66 -0.57 4.6e-12 Vitiligo; TGCT cis rs9976767 0.608 rs2277797 chr21:43823910 A/G cg23042151 chr21:43824109 UBASH3A -0.22 -4.87 -0.4 3.4e-6 Type 1 diabetes; TGCT cis rs1008375 0.966 rs10939736 chr4:17581617 T/A cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11761231 1.000 rs4348414 chr7:131369298 C/T cg23399222 chr7:130417715 KLF14 0.25 4.6 0.38 1.04e-5 Rheumatoid arthritis; TGCT cis rs10431058 0.930 rs11212297 chr11:107475371 T/C cg18204760 chr11:107461044 ELMOD1;LOC643923 0.74 7.08 0.54 9.56e-11 Common traits (Other); TGCT cis rs11264213 0.591 rs538638 chr1:36534644 G/T cg27506609 chr1:36549197 TEKT2 -0.31 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT cis rs7267979 0.586 rs6050431 chr20:25183908 C/T cg03522245 chr20:25566470 NINL 0.5 5.27 0.43 5.88e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs56104184 0.775 rs56349331 chr19:49403009 T/A cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs62244186 0.659 rs7649834 chr3:44503732 C/T cg10263370 chr3:44754102 ZNF502 -0.39 -4.8 -0.4 4.41e-6 Depressive symptoms; TGCT cis rs2980439 0.607 rs2980419 chr8:8114141 A/T cg15556689 chr8:8085844 FLJ10661 0.75 6.78 0.52 4.3e-10 Neuroticism; TGCT cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg03188948 chr7:1209495 NA 0.7 6.21 0.49 7.43e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs67311347 0.956 rs12633446 chr3:40505661 G/A cg17264618 chr3:40429014 ENTPD3 -0.33 -4.8 -0.4 4.51e-6 Renal cell carcinoma; TGCT cis rs2228479 0.850 rs12597296 chr16:89822331 C/T cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs911263 0.563 rs12883719 chr14:68810217 G/T cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs2933343 0.700 rs789239 chr3:128633808 T/C cg11901034 chr3:128598214 ACAD9 -0.63 -6.04 -0.48 1.68e-8 IgG glycosylation; TGCT cis rs9810089 0.843 rs556788 chr3:136027549 A/G cg12473912 chr3:136751656 NA 0.35 4.91 0.4 2.77e-6 Gestational age at birth (child effect); TGCT cis rs614226 0.744 rs787832 chr12:120986801 A/G cg10072921 chr12:121022843 NA -0.44 -4.74 -0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs7584330 0.554 rs6760913 chr2:238400702 C/T cg14458575 chr2:238380390 NA 0.55 5.27 0.43 5.73e-7 Prostate cancer; TGCT cis rs3858526 0.959 rs4758219 chr11:5951846 G/C cg05234568 chr11:5960015 NA -0.48 -4.77 -0.39 5.08e-6 DNA methylation (variation); TGCT cis rs11718455 0.881 rs17076257 chr3:44006787 C/T cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg10117171 chr1:25599238 RHD -0.32 -5.17 -0.42 9e-7 Erythrocyte sedimentation rate; TGCT cis rs597539 0.652 rs514296 chr11:68654182 G/T cg21963583 chr11:68658836 MRPL21 0.37 6.24 0.49 6.47e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs909674 0.818 rs5757678 chr22:39843409 A/G cg02038168 chr22:39784481 NA 0.67 5.22 0.42 7.39e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs908922 0.676 rs491077 chr1:152519570 C/A cg20991723 chr1:152506922 NA 0.45 6.09 0.48 1.33e-8 Hair morphology; TGCT cis rs6461049 0.800 rs3800909 chr7:2159594 C/G cg04267008 chr7:1944627 MAD1L1 -0.34 -4.57 -0.38 1.14e-5 Schizophrenia; TGCT cis rs9650657 0.572 rs4841465 chr8:10819854 C/T cg21775007 chr8:11205619 TDH -0.53 -4.97 -0.41 2.22e-6 Neuroticism; TGCT cis rs6089584 0.566 rs6061972 chr20:60610245 C/T cg13770153 chr20:60521292 NA -0.39 -4.77 -0.39 5.17e-6 Body mass index; TGCT cis rs1215050 0.791 rs9993992 chr4:98810851 C/G cg05340658 chr4:99064831 C4orf37 0.44 5.57 0.45 1.53e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs797680 0.754 rs10874777 chr1:93862020 T/C cg17826107 chr1:92977322 EVI5 -0.23 -5.41 -0.44 3.14e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9653442 1.000 rs7580200 chr2:100811903 G/T cg07810366 chr2:100720526 AFF3 0.46 7.66 0.57 4.58e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4478858 0.735 rs6676354 chr1:31800746 A/T cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs9291683 0.668 rs2241474 chr4:10086015 T/C cg00071950 chr4:10020882 SLC2A9 0.58 6.28 0.49 5.18e-9 Bone mineral density; TGCT cis rs7119 0.717 rs12910512 chr15:77817253 C/A cg27398640 chr15:77910606 LINGO1 -0.26 -4.65 -0.39 8.42e-6 Type 2 diabetes; TGCT cis rs939574 0.656 rs6710315 chr2:220137991 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.06 -5.13 -0.42 1.07e-6 Platelet distribution width; TGCT cis rs1215050 0.791 rs2865942 chr4:98737709 G/C cg05340658 chr4:99064831 C4orf37 0.44 5.63 0.45 1.15e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2050392 0.894 rs2480277 chr10:30703513 G/T cg18806716 chr10:30721971 MAP3K8 0.47 5.59 0.45 1.35e-7 Inflammatory bowel disease; TGCT cis rs9858542 0.953 rs9878943 chr3:49434654 G/A cg03060546 chr3:49711283 APEH -0.63 -5.49 -0.44 2.18e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1799949 0.931 rs34474989 chr17:41445410 A/T cg23758822 chr17:41437982 NA 0.71 6.99 0.53 1.49e-10 Menopause (age at onset); TGCT cis rs11785400 0.762 rs7017931 chr8:143726728 A/G cg10596483 chr8:143751796 JRK 0.53 5.3 0.43 5.12e-7 Schizophrenia; TGCT cis rs826838 0.967 rs826855 chr12:39114888 T/C cg26384229 chr12:38710491 ALG10B -0.86 -7.76 -0.57 2.68e-12 Heart rate; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs4727027 0.727 rs3801980 chr7:148878620 T/A cg23583168 chr7:148888333 NA -0.68 -7.82 -0.57 1.98e-12 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7208859 0.573 rs4055105 chr17:29102550 A/G cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1635 0.826 rs3800324 chr6:28264681 G/A cg15743358 chr6:28303923 ZNF323 -1.34 -5.96 -0.47 2.44e-8 Schizophrenia; TGCT cis rs7945705 0.902 rs10743093 chr11:8869129 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.42 4.86 0.4 3.53e-6 Hemoglobin concentration; TGCT cis rs9486719 0.843 rs3860230 chr6:97036560 T/A cg18709589 chr6:96969512 KIAA0776 -0.77 -6.26 -0.49 5.65e-9 Migraine;Coronary artery disease; TGCT trans rs9383153 1.000 rs2073518 chr6:16332730 T/C cg19402885 chr12:15475236 PTPRO 0.92 6.69 0.51 6.85e-10 Gambling; TGCT cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs3741151 1.000 rs75912489 chr11:73073846 G/A cg17517138 chr11:73019481 ARHGEF17 0.94 4.71 0.39 6.45e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs17401966 0.867 rs10492973 chr1:10398985 T/C cg19773385 chr1:10388646 KIF1B -0.23 -5.45 -0.44 2.63e-7 Hepatocellular carcinoma; TGCT cis rs55962025 0.883 rs82332 chr4:3225466 A/G cg06533319 chr4:3265114 C4orf44 0.24 4.72 0.39 6.24e-6 Parental longevity (mother's age at death); TGCT cis rs709400 0.663 rs11628213 chr14:103952453 A/C cg26031613 chr14:104095156 KLC1 0.85 9.5 0.65 2.07e-16 Body mass index; TGCT cis rs3008870 1.000 rs3008859 chr1:67390999 G/C cg11518657 chr1:67396239 MIER1 0.52 4.53 0.38 1.39e-5 Lymphocyte percentage of white cells; TGCT cis rs10504229 1.000 rs67546820 chr8:58168567 G/A cg22535103 chr8:58192502 C8orf71 -0.4 -5.13 -0.42 1.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.925 rs9881860 chr3:49352522 A/T cg07636037 chr3:49044803 WDR6 0.72 5.8 0.46 5.09e-8 Menarche (age at onset); TGCT cis rs7949030 0.622 rs34894392 chr11:62374821 A/G cg11742103 chr11:62369870 EML3;MTA2 0.6 8.72 0.62 1.53e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg07636037 chr3:49044803 WDR6 -0.89 -9.27 -0.64 7.32e-16 Menarche (age at onset); TGCT cis rs6951245 0.882 rs10256720 chr7:1210825 C/G cg23708337 chr7:1209742 NA 0.71 6.31 0.49 4.42e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg20007245 chr22:24372913 LOC391322 0.7 6.93 0.53 2.09e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2188554 0.740 rs213944 chr7:117190066 C/T cg08576598 chr7:116962626 WNT2 -0.36 -4.64 -0.38 8.54e-6 Esophageal adenocarcinoma; TGCT cis rs12449000 1 rs12449000 chr16:89872970 T/C cg04287289 chr16:89883240 FANCA 0.94 11.27 0.71 1.04e-20 Schizophrenia; TGCT cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg26818010 chr10:134567672 INPP5A -0.35 -4.48 -0.37 1.65e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11690935 0.632 rs12991740 chr2:172885996 C/T cg13550731 chr2:172543902 DYNC1I2 0.64 5.65 0.45 1.02e-7 Schizophrenia; TGCT cis rs9916302 0.904 rs8076494 chr17:37516722 A/G cg15445000 chr17:37608096 MED1 -0.32 -5.02 -0.41 1.79e-6 Glomerular filtration rate (creatinine); TGCT cis rs10256972 0.504 rs3735687 chr7:1066297 A/G cg16145915 chr7:1198662 ZFAND2A -0.49 -5.61 -0.45 1.28e-7 Longevity;Endometriosis; TGCT cis rs4776059 1.000 rs12914502 chr15:52911335 A/G cg25063058 chr15:52860530 ARPP19 0.53 4.76 0.39 5.22e-6 Schizophrenia; TGCT cis rs2228479 0.702 rs2074963 chr16:89877269 T/C cg06558623 chr16:89946397 TCF25 0.57 4.88 0.4 3.2e-6 Skin colour saturation; TGCT trans rs13064411 0.542 rs7631335 chr3:113209166 C/T cg00307254 chr3:126706825 PLXNA1 0.34 6.72 0.52 5.79e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs2224391 0.628 rs2753223 chr6:5244317 C/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs4851266 0.898 rs13010010 chr2:100852734 C/T cg22139774 chr2:100720529 AFF3 -0.32 -4.72 -0.39 6.3e-6 Educational attainment; TGCT cis rs1994135 0.692 rs1579909 chr12:33694780 T/C cg06521331 chr12:34319734 NA -0.3 -4.69 -0.39 6.97e-6 Resting heart rate; TGCT cis rs7666738 0.830 rs13101766 chr4:98957696 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9303401 0.659 rs62081314 chr17:56778328 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs12135062 0.755 rs1553287 chr1:3101277 G/A cg00254258 chr1:3105189 PRDM16 -0.31 -4.97 -0.41 2.18e-6 Migraine; TGCT cis rs74233809 1.000 rs11191519 chr10:104784918 C/T cg05855489 chr10:104503620 C10orf26 0.76 4.53 0.38 1.36e-5 Birth weight; TGCT cis rs3008870 0.583 rs2031495 chr1:67421714 G/T cg08660285 chr1:67390436 MIER1;WDR78 0.97 8.16 0.59 3.17e-13 Lymphocyte percentage of white cells; TGCT cis rs514406 0.525 rs269291 chr1:53189297 C/T cg22166914 chr1:53195759 ZYG11B 0.5 9.38 0.64 4.09e-16 Monocyte count; TGCT cis rs57504626 1 rs57504626 chr19:19720399 C/T cg03709012 chr19:19516395 GATAD2A 1.04 5.1 0.42 1.26e-6 Total cholesterol change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs4713118 0.955 rs9368529 chr6:27684631 G/A cg10876282 chr6:28092338 ZSCAN16 0.51 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs1577917 0.876 rs4618490 chr6:86518403 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.51 -0.44 1.99e-7 Response to antipsychotic treatment; TGCT cis rs1008375 0.966 rs6833808 chr4:17652526 T/A cg10189774 chr4:17578691 LAP3 0.61 5.33 0.43 4.55e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg03188948 chr7:1209495 NA 0.49 7.01 0.53 1.32e-10 Longevity;Endometriosis; TGCT cis rs9814567 1.000 rs1863913 chr3:134200205 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -9.28 -0.64 7.11e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11249608 0.636 rs13361077 chr5:178449174 G/C cg21905437 chr5:178450457 ZNF879 0.45 4.48 0.37 1.67e-5 Pubertal anthropometrics; TGCT trans rs4650994 0.525 rs10913574 chr1:178536482 G/C cg05059571 chr16:84539110 KIAA1609 -0.54 -11.05 -0.7 3.58e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs28595532 0.920 rs116146507 chr4:119749556 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs1997103 0.822 rs940878 chr7:55419663 A/G cg17469321 chr7:55412551 NA 0.61 5.91 0.47 3.03e-8 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1670533 1.000 rs10084888 chr4:1053814 G/T cg27284194 chr4:1044797 NA 0.67 5.77 0.46 5.9e-8 Recombination rate (females); TGCT cis rs9303401 0.659 rs16943326 chr17:57050365 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.38 0.5 3.24e-9 Cognitive test performance; TGCT trans rs8073060 0.586 rs2523116 chr17:34025460 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2120019 1.000 rs8033837 chr15:75353975 A/C cg11632617 chr15:75315747 PPCDC -0.32 -4.67 -0.39 7.58e-6 Blood trace element (Zn levels); TGCT cis rs9611519 0.780 rs3171692 chr22:41642212 C/T cg03806693 chr22:41940476 POLR3H -0.75 -7.07 -0.54 9.78e-11 Neuroticism; TGCT cis rs6728642 0.708 rs56807297 chr2:97861340 A/C cg26665480 chr2:98280029 ACTR1B -0.98 -5.58 -0.45 1.42e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs1008375 1.000 rs10805357 chr4:17652352 G/A cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6570726 0.791 rs435671 chr6:145881215 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.962 rs7267951 chr20:61665979 A/G cg08564027 chr20:61660810 NA 0.37 6.64 0.51 8.85e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs11098499 0.954 rs7681544 chr4:120411255 T/C cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs10504229 0.639 rs17331850 chr8:58113538 G/T cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT trans rs57221529 0.709 rs111352378 chr5:577079 G/A cg25482853 chr8:67687455 SGK3 1.16 10.5 0.69 7.91e-19 Lung disease severity in cystic fibrosis; TGCT trans rs10435719 0.678 rs74724594 chr8:11790576 C/A cg15556689 chr8:8085844 FLJ10661 0.76 7.18 0.54 5.62e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs12134133 1.000 rs11580382 chr1:207418392 A/C cg02152968 chr1:207494213 CD55 0.61 4.83 0.4 3.92e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7829975 0.514 rs2920983 chr8:8268063 G/C cg06636001 chr8:8085503 FLJ10661 0.71 6.22 0.49 7.04e-9 Mood instability; TGCT cis rs782590 0.517 rs13013133 chr2:55889466 G/A cg03859395 chr2:55845619 SMEK2 -0.62 -5.17 -0.42 8.94e-7 Metabolic syndrome; TGCT cis rs7843479 1.000 rs2054711 chr8:21818060 A/G cg17168535 chr8:21777572 XPO7 0.65 5.99 0.47 2.14e-8 Mean corpuscular volume; TGCT cis rs4478858 0.684 rs11579845 chr1:31736248 A/G cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs12497850 0.931 rs9682444 chr3:48852639 A/G cg06212747 chr3:49208901 KLHDC8B 0.61 5.62 0.45 1.2e-7 Parkinson's disease; TGCT cis rs10927875 0.541 rs1739842 chr1:16342848 T/G cg22431228 chr1:16359049 CLCNKA -0.29 -6.02 -0.48 1.8e-8 Dilated cardiomyopathy; TGCT cis rs7666738 0.830 rs4699574 chr4:98725544 C/T cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs11992162 0.529 rs6995037 chr8:11780887 A/G cg15556689 chr8:8085844 FLJ10661 -0.79 -6.77 -0.52 4.69e-10 Monocyte count; TGCT cis rs459571 0.796 rs10993894 chr9:136884511 C/T cg14405625 chr9:136855902 VAV2 -0.3 -4.44 -0.37 1.99e-5 Platelet distribution width; TGCT cis rs6138458 1.000 rs227618 chr20:24909472 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs6500602 0.787 rs7204624 chr16:4459834 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.42 5.22 0.42 7.34e-7 Schizophrenia; TGCT cis rs617791 0.530 rs7952056 chr11:65744597 C/T cg09783858 chr11:65769428 EIF1AD;BANF1 0.49 4.48 0.37 1.67e-5 Breast cancer; TGCT cis rs172166 0.611 rs203882 chr6:28078502 G/A cg10876282 chr6:28092338 ZSCAN16 0.51 4.69 0.39 6.99e-6 Cardiac Troponin-T levels; TGCT cis rs6952808 1.000 rs6957894 chr7:1887362 G/A cg22963979 chr7:1858916 MAD1L1 -0.32 -4.95 -0.41 2.39e-6 Bipolar disorder and schizophrenia; TGCT cis rs6665290 0.904 rs2297418 chr1:227192579 A/C cg10327440 chr1:227177885 CDC42BPA -1.0 -20.5 -0.88 1.18e-41 Myeloid white cell count; TGCT cis rs8180040 0.620 rs1811652 chr3:47208698 C/G cg27129171 chr3:47204927 SETD2 -0.7 -8.33 -0.6 1.26e-13 Colorectal cancer; TGCT cis rs9291683 0.588 rs3733586 chr4:9997534 C/T cg00071950 chr4:10020882 SLC2A9 0.7 9.39 0.64 3.88e-16 Bone mineral density; TGCT cis rs7584330 1.000 rs7584330 chr2:238387228 A/G cg14458575 chr2:238380390 NA 0.49 7.53 0.56 9.28e-12 Prostate cancer; TGCT cis rs28595532 0.841 rs116093021 chr4:119763872 C/G cg21605333 chr4:119757512 SEC24D 1.55 8.04 0.59 6.15e-13 Cannabis dependence symptom count; TGCT cis rs1005224 0.889 rs2059382 chr14:76158916 T/C cg04684003 chr14:76127793 TTLL5;C14orf1 -0.67 -5.99 -0.47 2.07e-8 Large artery stroke; TGCT cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9297145 0.761 rs112155177 chr7:98747963 C/T cg05967295 chr7:98741636 SMURF1 1.01 12.87 0.76 1.33e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs7267979 0.932 rs4280527 chr20:25544014 A/G cg14121845 chr20:25566513 NINL 0.48 5.16 0.42 9.69e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3806843 0.576 rs251370 chr5:140246287 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.42 5.03 0.41 1.69e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs72781680 0.898 rs72788302 chr2:24107246 C/T cg08917208 chr2:24149416 ATAD2B 0.9 5.6 0.45 1.29e-7 Lymphocyte counts; TGCT cis rs12541335 0.639 rs4565458 chr8:22154133 T/C cg18135555 chr8:22132992 PIWIL2 0.29 5.71 0.46 7.76e-8 Hypertriglyceridemia; TGCT cis rs9911578 1.000 rs391370 chr17:56675050 A/C cg12560992 chr17:57184187 TRIM37 0.76 9.16 0.64 1.32e-15 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.656 rs11764212 chr7:2067593 C/A cg22963979 chr7:1858916 MAD1L1 -0.39 -6.16 -0.48 9.33e-9 Bipolar disorder and schizophrenia; TGCT cis rs4727027 0.782 rs10245343 chr7:148796333 T/C cg23583168 chr7:148888333 NA -0.65 -7.35 -0.55 2.36e-11 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4234284 0.556 rs7650549 chr3:126968288 C/T cg26312807 chr3:127057048 NA -0.5 -4.6 -0.38 1.03e-5 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs67311347 1.000 rs9882171 chr3:40518821 G/A cg13683864 chr3:40499215 RPL14 -1.14 -12.22 -0.74 4.89e-23 Renal cell carcinoma; TGCT cis rs4665809 1.000 rs6546766 chr2:26328680 T/C cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs6951245 1.000 rs76388414 chr7:1100694 G/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs909674 0.818 rs5757681 chr22:39845547 A/G cg24399712 chr22:39784796 NA -1.06 -11.27 -0.71 1.01e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs854765 0.624 rs9902941 chr17:17733760 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.52 -0.5 1.64e-9 Total body bone mineral density; TGCT cis rs12541335 0.536 rs4266653 chr8:22169087 A/G cg26039829 chr8:22132926 PIWIL2 0.25 4.8 0.4 4.56e-6 Hypertriglyceridemia; TGCT cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 6.45 0.5 2.24e-9 Schizophrenia; TGCT cis rs853679 0.517 rs9380057 chr6:28104634 G/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.9 7.25 0.55 3.93e-11 Platelet count; TGCT cis rs7586879 0.639 rs13407913 chr2:25097644 A/G cg15423357 chr2:25149977 NA 0.46 4.47 0.37 1.72e-5 Body mass index; TGCT cis rs9486715 0.867 rs9486181 chr6:96868132 G/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs6570726 0.791 rs12205752 chr6:145896118 A/G cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7412746 0.611 rs752376 chr1:150941381 C/T cg09365446 chr1:150670422 GOLPH3L 0.34 4.7 0.39 6.76e-6 Melanoma; TGCT cis rs11098499 0.863 rs3736115 chr4:120488703 A/G cg09307838 chr4:120376055 NA -0.71 -6.1 -0.48 1.22e-8 Corneal astigmatism; TGCT cis rs36051895 0.659 rs10121491 chr9:5046935 T/C cg02405213 chr9:5042618 JAK2 -0.78 -10.85 -0.7 1.1e-19 Pediatric autoimmune diseases; TGCT trans rs7819412 0.775 rs4841489 chr8:10936811 A/G cg06636001 chr8:8085503 FLJ10661 -0.77 -7.08 -0.54 9.66e-11 Triglycerides; TGCT cis rs77106637 0.932 rs3814730 chr11:72555553 G/A cg03713592 chr11:72463424 ARAP1 0.87 5.88 0.47 3.52e-8 Type 2 diabetes; TGCT cis rs35146811 0.844 rs10281368 chr7:99655897 A/G cg13334819 chr7:99746414 C7orf59 -0.81 -7.0 -0.53 1.43e-10 Coronary artery disease; TGCT cis rs7523050 0.730 rs7519107 chr1:109399367 A/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs6088580 0.634 rs4911422 chr20:32999345 T/C cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs941873 0.868 rs2145998 chr10:81121696 T/A cg09469691 chr10:81107165 PPIF 0.55 5.42 0.44 2.93e-7 Height; TGCT cis rs7829975 0.582 rs11783950 chr8:8597831 A/C cg06636001 chr8:8085503 FLJ10661 -0.66 -5.81 -0.46 4.89e-8 Mood instability; TGCT cis rs10791323 0.569 rs1119851 chr11:133742842 T/C cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.92 -6.8 -0.52 3.96e-10 Gut microbiome composition (summer); TGCT cis rs6459788 0.693 rs11981578 chr7:157250133 C/T cg06271696 chr7:157225062 NA -0.27 -4.94 -0.41 2.46e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT trans rs12655019 0.920 rs12657064 chr5:56220999 G/A cg25190722 chr1:3801660 DFFB 0.65 7.42 0.55 1.63e-11 Breast cancer (early onset); TGCT cis rs74054849 0.571 rs77157441 chr1:15941508 G/A cg05660106 chr1:15850417 CASP9 0.86 4.47 0.37 1.71e-5 Alcoholic chronic pancreatitis; TGCT cis rs35522438 1 rs35522438 chr7:91872872 A/AT cg17063962 chr7:91808500 NA 0.91 9.85 0.66 2.94e-17 Breast cancer; TGCT cis rs2224391 0.628 rs2753222 chr6:5242075 T/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.12 -0.48 1.16e-8 Height; TGCT cis rs1552244 0.572 rs17032426 chr3:10167112 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg11644478 chr21:40555479 PSMG1 -0.62 -5.73 -0.46 7.03e-8 Cognitive function; TGCT cis rs4654899 0.931 rs10753506 chr1:21141022 A/G cg01072550 chr1:21505969 NA 0.49 7.71 0.57 3.49e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2153535 0.580 rs2143355 chr6:8517856 T/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs7769051 1.000 rs7761365 chr6:133101561 T/A cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs9549367 0.713 rs11620600 chr13:113829090 G/A cg00898013 chr13:113819073 PROZ -0.55 -7.05 -0.53 1.12e-10 Platelet distribution width; TGCT cis rs28595532 0.920 rs114547492 chr4:119773078 G/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs7772486 0.875 rs2777483 chr6:146329235 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.98 0.41 2.12e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13191362 0.872 rs73020362 chr6:163005737 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1800813 0.515 rs34148754 chr4:55057049 G/A cg17187183 chr4:55093834 PDGFRA 0.41 4.9 0.4 2.94e-6 Corneal curvature; TGCT cis rs7552404 0.731 rs2029683 chr1:76341643 T/G cg10523679 chr1:76189770 ACADM -0.83 -7.8 -0.57 2.24e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg03404566 chr17:6899310 ALOX12 0.47 5.26 0.43 6.17e-7 Tonsillectomy; TGCT cis rs9818758 0.607 rs73074866 chr3:49626666 C/T cg00383909 chr3:49044727 WDR6 1.31 6.63 0.51 9.3e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7523273 0.565 rs2985104 chr1:207892012 C/T cg22525895 chr1:207977042 MIR29B2 -0.35 -5.67 -0.45 9.4e-8 Schizophrenia; TGCT cis rs3091242 0.836 rs35346083 chr1:25788425 C/A cg09222892 chr1:25734099 RHCE 0.4 6.43 0.5 2.46e-9 Erythrocyte sedimentation rate; TGCT cis rs7246657 0.722 rs2972438 chr19:38210847 A/G cg03611452 chr19:38183253 ZNF781 0.53 4.44 0.37 1.95e-5 Coronary artery calcification; TGCT cis rs7772486 0.875 rs1929523 chr6:146339989 T/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.56 -0.38 1.23e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10197940 0.578 rs6718372 chr2:152345871 C/G cg19508488 chr2:152266495 RIF1 0.59 4.98 0.41 2.11e-6 Lung cancer; TGCT cis rs17152411 1.000 rs17152411 chr10:126649516 A/G cg07906193 chr10:126599966 NA 0.37 4.64 0.38 8.78e-6 Height; TGCT cis rs492146 0.765 rs316140 chr6:52846188 C/T cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs7666738 0.830 rs35822567 chr4:98654138 G/A cg17366294 chr4:99064904 C4orf37 0.62 6.4 0.5 2.94e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9487051 0.714 rs6902892 chr6:109627601 G/T cg01475377 chr6:109611718 NA -0.3 -4.73 -0.39 6.01e-6 Reticulocyte fraction of red cells; TGCT cis rs6939532 0.522 rs13218591 chr6:26376832 T/C cg05738196 chr6:26577821 NA -0.51 -4.96 -0.41 2.22e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6951245 1.000 rs78861357 chr7:1095418 C/T cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7267979 0.932 rs449370 chr20:25451180 A/G cg14121845 chr20:25566513 NINL -0.5 -5.38 -0.43 3.61e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs4332037 0.950 rs10267593 chr7:1937261 G/A cg25206134 chr2:45395956 NA 0.96 7.99 0.58 8.02e-13 Bipolar disorder; TGCT cis rs9926296 0.593 rs6500456 chr16:89888341 T/C cg27121462 chr16:89883253 FANCA 0.54 5.0 0.41 1.87e-6 Vitiligo; TGCT cis rs9534288 0.913 rs9534298 chr13:46625566 C/G cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs7208859 0.623 rs60890550 chr17:29030861 A/G cg14008862 chr17:28927542 LRRC37B2 0.76 4.63 0.38 9.23e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs13088645 0.532 rs9857134 chr3:134161607 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.66 6.03 0.48 1.71e-8 Coronary artery disease; TGCT cis rs929843 1 rs929843 chr16:70045748 A/C cg09409435 chr16:70099608 PDXDC2 0.85 7.28 0.55 3.36e-11 Menarche (age at onset); TGCT cis rs112591243 0.685 rs4819269 chr21:48023532 A/G cg05707788 chr21:47165437 NA 0.52 4.59 0.38 1.06e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs17253792 0.822 rs74935793 chr14:56143277 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs873946 0.648 rs1543593 chr10:134553185 A/T cg26818010 chr10:134567672 INPP5A -0.35 -4.48 -0.37 1.65e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2836974 0.627 rs8127986 chr21:40687211 A/T cg11890956 chr21:40555474 PSMG1 -0.77 -6.92 -0.53 2.13e-10 Cognitive function; TGCT cis rs10193935 0.901 rs10201586 chr2:42622594 C/G cg27598129 chr2:42591480 NA -0.37 -5.23 -0.42 7.1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6912958 0.559 rs2985039 chr6:88041757 A/G cg04972856 chr6:88032051 C6orf162;GJB7 0.39 4.48 0.37 1.66e-5 Monocyte percentage of white cells; TGCT trans rs551517 0.541 rs498328 chr9:113643828 C/G cg18410444 chr5:89825535 LYSMD3 -0.65 -6.62 -0.51 9.91e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs7666738 0.800 rs7684523 chr4:98983175 G/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs908922 0.676 rs1053590 chr1:152488428 T/C cg20991723 chr1:152506922 NA 0.48 6.72 0.52 5.75e-10 Hair morphology; TGCT cis rs10479542 0.892 rs7736163 chr5:178980316 G/C cg19626725 chr5:178986131 RUFY1 0.45 5.7 0.46 8.11e-8 Lung cancer; TGCT trans rs7618501 1.000 rs11709680 chr3:49745188 C/T cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs77741769 0.571 rs4766979 chr12:121281748 G/A cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.58e-5 Mean corpuscular volume; TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs7246657 0.943 rs10415358 chr19:37808863 C/A cg18154014 chr19:37997991 ZNF793 0.98 6.49 0.5 1.87e-9 Coronary artery calcification; TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg18722847 chr3:44754129 ZNF502 -0.4 -4.49 -0.37 1.59e-5 Depressive symptoms; TGCT cis rs514406 0.861 rs1571979 chr1:53237526 G/A cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs12681288 0.862 rs34510005 chr8:1018943 T/C cg06709756 chr8:1339049 NA -0.23 -4.52 -0.38 1.42e-5 Schizophrenia; TGCT cis rs68170813 0.559 rs6964798 chr7:106933013 C/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs6840360 0.571 rs7664663 chr4:152508014 G/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs8066754 chr17:61816590 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs1215050 0.791 rs7688192 chr4:98900798 G/T cg17366294 chr4:99064904 C4orf37 -0.53 -5.69 -0.45 8.67e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs56104184 0.830 rs17272645 chr19:49342366 C/G cg21252483 chr19:49399788 TULP2 0.36 4.99 0.41 2e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6894249 0.874 rs11745587 chr5:131796922 A/G cg02551604 chr5:131831745 NA 0.54 5.39 0.44 3.45e-7 Asthma; TGCT cis rs11696501 0.637 rs6104298 chr20:44327774 A/G cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs6933660 0.646 rs6911456 chr6:151778934 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -1.05 -14.06 -0.78 1.99e-27 Menarche (age at onset); TGCT cis rs6089584 0.888 rs2386555 chr20:60612373 C/T cg13665807 chr20:60559372 TAF4 -0.46 -4.94 -0.41 2.48e-6 Body mass index; TGCT cis rs35146811 0.844 rs59261051 chr7:99650429 C/T cg13334819 chr7:99746414 C7orf59 -0.81 -6.82 -0.52 3.49e-10 Coronary artery disease; TGCT cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs57920188 0.584 rs10915657 chr1:4092904 T/C cg20703997 chr1:4087676 NA 0.49 5.5 0.44 2.03e-7 Interleukin-17 levels; TGCT cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg20637647 chr7:64974828 NA 0.9 5.06 0.41 1.45e-6 Diabetic kidney disease; TGCT cis rs4820539 1.000 rs916583 chr22:23469267 C/T cg21100191 chr22:23484243 RTDR1 0.89 10.51 0.69 7.38e-19 Bone mineral density; TGCT cis rs826838 0.935 rs1601579 chr12:39178606 G/C cg26384229 chr12:38710491 ALG10B 1.0 8.98 0.63 3.56e-15 Heart rate; TGCT cis rs6570726 0.846 rs453834 chr6:145886261 T/C cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs8063761 0.689 rs4785763 chr16:90066936 G/T cg08547343 chr16:90038815 CENPBD1;AFG3L1 -0.52 -4.6 -0.38 1.03e-5 Squamous cell carcinoma; TGCT cis rs9527 0.641 rs34130454 chr10:104903638 A/G cg04362960 chr10:104952993 NT5C2 0.68 5.76 0.46 6.3e-8 Arsenic metabolism; TGCT cis rs1163251 0.902 rs483360 chr1:120200606 C/T cg19096424 chr1:120255104 PHGDH -0.57 -5.27 -0.43 5.97e-7 Blood metabolite levels; TGCT trans rs7726839 0.540 rs3749618 chr5:602650 A/G cg25482853 chr8:67687455 SGK3 1.22 10.58 0.69 4.8e-19 Obesity-related traits; TGCT cis rs9303401 0.659 rs16943326 chr17:57050365 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.57 0.38 1.16e-5 Cognitive test performance; TGCT cis rs6570726 0.791 rs408443 chr6:145874643 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs3733585 0.673 rs4519796 chr4:9955936 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7811142 1.000 rs60257855 chr7:100026780 G/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.6 -0.65 1.17e-16 Platelet count; TGCT cis rs7267979 0.816 rs6115094 chr20:25210827 A/G cg16686733 chr20:25566563 NINL 0.48 4.45 0.37 1.86e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs55883249 0.957 rs10495572 chr2:9734859 C/G cg23886495 chr2:9695866 ADAM17 -0.81 -5.0 -0.41 1.93e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs61776719 0.500 rs11210866 chr1:38449565 T/C cg26398791 chr1:38455867 SF3A3 -0.47 -4.56 -0.38 1.19e-5 Coronary artery disease; TGCT cis rs868036 0.718 rs3784710 chr15:68072458 T/C cg05925327 chr15:68127851 NA -0.5 -4.81 -0.4 4.34e-6 Restless legs syndrome; TGCT cis rs13256369 0.950 rs13270006 chr8:8574197 C/A cg17143192 chr8:8559678 CLDN23 0.63 5.93 0.47 2.8e-8 Obesity-related traits; TGCT cis rs875971 0.862 rs6460282 chr7:65691246 T/C cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.94e-6 Aortic root size; TGCT cis rs1552244 0.572 rs6797536 chr3:10168802 C/T cg00149659 chr3:10157352 C3orf10 -1.2 -7.56 -0.56 7.9e-12 Alzheimer's disease; TGCT cis rs12681288 0.963 rs35220148 chr8:1027602 G/A cg04851639 chr8:1020857 NA -0.35 -6.06 -0.48 1.5e-8 Schizophrenia; TGCT cis rs7246657 0.551 rs10407224 chr19:37651470 G/T cg24025825 chr19:37761650 NA -0.3 -4.82 -0.4 4.17e-6 Coronary artery calcification; TGCT cis rs11098499 0.863 rs1383533 chr4:120434576 G/A cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs2486012 1.000 rs783301 chr1:44369009 C/T cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs2760061 0.819 rs708114 chr1:228197496 G/A cg18477163 chr1:228402036 OBSCN 0.34 7.19 0.54 5.33e-11 Diastolic blood pressure; TGCT cis rs796364 1.000 rs1509835 chr2:200814809 C/G cg17644776 chr2:200775616 C2orf69 0.3 4.77 0.39 5.12e-6 Schizophrenia; TGCT cis rs2153535 0.601 rs969420 chr6:8451966 T/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs2180341 0.618 rs12529077 chr6:127634244 G/T cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs2204008 0.643 rs1315347 chr12:38162494 C/T cg26384229 chr12:38710491 ALG10B -0.58 -5.08 -0.42 1.33e-6 Bladder cancer; TGCT cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs600231 0.665 rs2105608 chr11:65228618 T/A cg17120908 chr11:65337727 SSSCA1 -0.53 -4.86 -0.4 3.43e-6 Bone mineral density; TGCT trans rs916888 0.773 rs199443 chr17:44819565 C/T cg07870213 chr5:140052090 DND1 0.65 7.75 0.57 2.79e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6964587 1.000 rs7802668 chr7:91648939 A/G cg22709100 chr7:91322751 NA 0.28 4.49 0.37 1.61e-5 Breast cancer; TGCT cis rs5750830 0.594 rs1010170 chr22:39778327 C/T cg24399712 chr22:39784796 NA 1.0 11.31 0.71 8.1899999999999992e-21 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg08683831 chr4:1404607 NA -0.46 -4.43 -0.37 2.01e-5 Obesity-related traits; TGCT cis rs6671200 0.920 rs11165339 chr1:95674064 T/C cg20701556 chr1:95698924 RWDD3 -0.65 -5.58 -0.45 1.43e-7 Stearic acid (18:0) levels; TGCT cis rs854765 0.547 rs2955356 chr17:17964717 G/A cg09796270 chr17:17721594 SREBF1 -0.26 -5.17 -0.42 9.05e-7 Total body bone mineral density; TGCT cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg03517284 chr6:25882590 NA -0.61 -5.5 -0.44 2.12e-7 Intelligence (multi-trait analysis); TGCT cis rs1334894 0.901 rs7768598 chr6:35520651 A/G cg24281267 chr6:35479648 TULP1 0.42 4.5 0.37 1.54e-5 Coronary artery disease; TGCT cis rs12681287 0.640 rs7832493 chr8:87371533 A/C cg27223183 chr8:87520930 FAM82B 0.9 6.71 0.52 6.12e-10 Caudate activity during reward; TGCT cis rs2839186 0.872 rs13052233 chr21:47707284 G/T cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg00934597 chr7:893267 UNC84A 0.2 4.49 0.37 1.58e-5 Perceived unattractiveness to mosquitoes; TGCT cis rs10489202 0.683 rs4657730 chr1:168072738 A/T cg24449463 chr1:168025552 DCAF6 -0.53 -5.62 -0.45 1.2e-7 Schizophrenia; TGCT cis rs2197308 0.765 rs11182900 chr12:37934009 C/T cg26384229 chr12:38710491 ALG10B 0.87 7.83 0.58 1.85e-12 Morning vs. evening chronotype; TGCT cis rs713587 0.563 rs11686663 chr2:25107759 C/T cg01884057 chr2:25150051 NA 0.31 5.96 0.47 2.43e-8 Body mass index in non-asthmatics; TGCT cis rs73198271 1.000 rs11784958 chr8:8607781 C/A ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs6879260 1.000 rs6874653 chr5:179730843 A/G cg23221052 chr5:179740743 GFPT2 -0.35 -5.6 -0.45 1.34e-7 Height; TGCT cis rs514406 0.861 rs554760 chr1:53266749 G/A cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs6988636 0.534 rs73337894 chr8:124123010 T/C cg27053337 chr8:124217698 FAM83A 0.56 4.9 0.4 2.88e-6 Urinary uromodulin levels; TGCT cis rs2762353 0.935 rs1165209 chr6:25801319 G/A cg03264133 chr6:25882463 NA -0.51 -5.37 -0.43 3.77e-7 Blood metabolite levels; TGCT cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg15659132 chr6:26577336 NA 0.86 10.81 0.7 1.36e-19 Intelligence (multi-trait analysis); TGCT cis rs10193935 1.000 rs10195776 chr2:42425098 G/A cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11651000 0.654 rs12451801 chr17:45820975 T/C cg06532163 chr17:45867833 NA 0.34 4.9 0.4 2.95e-6 IgG glycosylation; TGCT cis rs4765913 0.874 rs4765914 chr12:2420377 A/G cg14310533 chr12:2046230 NA 0.24 4.46 0.37 1.81e-5 Bipolar disorder; TGCT cis rs2836974 0.666 rs2836975 chr21:40663620 A/G cg11890956 chr21:40555474 PSMG1 -0.8 -7.62 -0.56 5.74e-12 Cognitive function; TGCT cis rs2456568 0.802 rs10831136 chr11:93636860 T/C cg14065697 chr11:93583672 C11orf90 -0.37 -4.63 -0.38 9.11e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs12579753 0.879 rs7958657 chr12:82135067 G/A cg07988820 chr12:82153109 PPFIA2 -0.68 -7.32 -0.55 2.7e-11 Resting heart rate; TGCT cis rs727505 0.954 rs59283092 chr7:124678282 T/C cg23710748 chr7:124431027 NA -0.26 -4.51 -0.38 1.49e-5 Lewy body disease; TGCT cis rs9560113 1.000 rs4773379 chr13:112176088 G/C cg14154082 chr13:112174009 NA 0.34 4.5 0.37 1.52e-5 Menarche (age at onset); TGCT cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg16145915 chr7:1198662 ZFAND2A -0.46 -5.47 -0.44 2.36e-7 Longevity;Endometriosis; TGCT cis rs11711311 1.000 rs2242108 chr3:113433903 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs909674 0.731 rs4821897 chr22:39835587 A/G cg05872129 chr22:39784769 NA -1.03 -10.02 -0.67 1.11e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10504229 0.645 rs35142596 chr8:58128151 C/T cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs1799949 1.000 rs2037075 chr17:41305826 G/T cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs1799949 1.000 rs8176120 chr17:41261233 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.73e-7 Menopause (age at onset); TGCT cis rs295140 1.000 rs7578220 chr2:201183701 A/G cg04283868 chr2:201171347 SPATS2L 0.65 6.67 0.51 7.63e-10 QT interval; TGCT cis rs17125944 0.505 rs2274275 chr14:53235728 G/T cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs3806843 0.520 rs246051 chr5:140326464 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs2727020 0.521 rs7930855 chr11:49521660 C/T cg11707556 chr5:10655725 ANKRD33B 0.42 8.63 0.61 2.5e-14 Coronary artery disease; TGCT cis rs9303401 0.614 rs3087762 chr17:56568680 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.71 6.74 0.52 5.45e-10 Cognitive test performance; TGCT cis rs36051895 0.659 rs61284219 chr9:5062816 C/A cg02405213 chr9:5042618 JAK2 -0.8 -11.72 -0.73 8.06e-22 Pediatric autoimmune diseases; TGCT cis rs12142240 0.698 rs68191463 chr1:46808695 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs9341808 0.754 rs1324121 chr6:80946077 A/G cg08355045 chr6:80787529 NA 0.29 5.1 0.42 1.23e-6 Sitting height ratio; TGCT cis rs4900538 0.892 rs4906208 chr14:102956489 G/C cg18135206 chr14:102964638 TECPR2 0.21 5.13 0.42 1.08e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs11167764 1.000 rs3761757 chr5:141488219 A/C cg23435118 chr5:141488016 NDFIP1 -0.28 -4.84 -0.4 3.83e-6 Crohn's disease; TGCT cis rs3540 0.553 rs4031431 chr15:90990782 G/T cg22089800 chr15:90895588 ZNF774 0.76 8.13 0.59 3.83e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7149242 0.961 rs7142683 chr14:101158882 A/G cg18089426 chr14:101175970 NA -0.45 -4.7 -0.39 6.79e-6 Platelet count; TGCT cis rs6430585 0.528 rs499483 chr2:136652524 G/A cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs9972944 0.692 rs8071561 chr17:63763434 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.24 -0.43 6.6e-7 Total body bone mineral density; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg01585852 chr22:24235823 MIF 0.22 4.82 0.4 4.16e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8177253 0.509 rs6762415 chr3:133478557 T/G cg08048268 chr3:133502702 NA -0.56 -6.53 -0.51 1.54e-9 Iron status biomarkers; TGCT cis rs1862618 0.525 rs2662016 chr5:56269047 A/G cg24531977 chr5:56204891 C5orf35 0.85 7.52 0.56 9.7e-12 Initial pursuit acceleration; TGCT cis rs60871478 0.636 rs73045423 chr7:893952 G/A cg00475322 chr7:917719 C7orf20 0.5 4.87 0.4 3.37e-6 Cerebrospinal P-tau181p levels; TGCT cis rs7944584 0.632 rs11039159 chr11:47294021 G/T cg20307385 chr11:47447363 PSMC3 0.79 7.81 0.57 2.08e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs6752107 0.935 rs10929322 chr2:234149702 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 -0.2 -4.91 -0.4 2.83e-6 Crohn's disease;Inflammatory bowel disease; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg22767166 chr8:49833685 SNAI2 0.84 6.62 0.51 9.69e-10 Gambling; TGCT cis rs9309473 0.583 rs11126397 chr2:73588733 C/T cg20560298 chr2:73613845 ALMS1 -0.41 -4.54 -0.38 1.31e-5 Metabolite levels; TGCT cis rs903263 0.965 rs6695305 chr1:84593401 T/A cg09664975 chr1:84543551 PRKACB 0.49 4.6 0.38 1.01e-5 Breast cancer (male); TGCT cis rs208520 0.706 rs851601 chr6:66893853 G/A cg07460842 chr6:66804631 NA -0.9 -9.33 -0.64 5.29e-16 Exhaled nitric oxide output; TGCT cis rs1801251 0.896 rs7573208 chr2:233696701 C/A cg08000102 chr2:233561755 GIGYF2 -0.59 -6.23 -0.49 6.64e-9 Coronary artery disease; TGCT cis rs8177253 1.000 rs3811647 chr3:133484029 G/A cg01448562 chr3:133502909 NA -0.33 -6.68 -0.51 7.33e-10 Iron status biomarkers; TGCT cis rs55823223 0.564 rs4572466 chr17:73846314 A/C cg08125733 chr17:73851984 WBP2 0.88 8.95 0.63 4.39e-15 Psoriasis; TGCT cis rs7258465 1.000 rs10409505 chr19:18590251 C/G cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs6089829 0.962 rs4809462 chr20:61661560 A/G cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT trans rs208520 0.690 rs6932475 chr6:66863155 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs9858542 1.000 rs4283605 chr3:49678651 A/G cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT trans rs8073060 0.544 rs8072676 chr17:33999517 C/T cg19694781 chr19:47549865 TMEM160 -0.59 -13.15 -0.76 2.9e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs910316 0.967 rs4899549 chr14:75647494 G/A cg23033748 chr14:75592666 NEK9 -0.29 -4.93 -0.41 2.55e-6 Height; TGCT cis rs2153535 0.601 rs2327054 chr6:8443130 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs8031584 0.578 rs1088473 chr15:31139298 A/G cg14829155 chr15:31115871 NA 0.36 4.72 0.39 6.14e-6 Huntington's disease progression; TGCT cis rs1005277 0.579 rs2505197 chr10:38393310 T/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs514406 0.505 rs431459 chr1:53183230 T/G cg22166914 chr1:53195759 ZYG11B 0.45 8.18 0.59 2.87e-13 Monocyte count; TGCT cis rs7829975 0.577 rs940032 chr8:8546343 C/T cg06636001 chr8:8085503 FLJ10661 -0.6 -5.18 -0.42 8.83e-7 Mood instability; TGCT cis rs597539 0.652 rs546382 chr11:68704264 C/T cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.82 7.52 0.56 9.42e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1372520 0.748 rs2737002 chr4:90753180 A/G cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs12681287 0.517 rs34596274 chr8:87517679 C/T cg19078186 chr8:87526527 CPNE3 -0.36 -4.49 -0.37 1.59e-5 Caudate activity during reward; TGCT cis rs7552167 0.925 rs3932664 chr1:24511663 G/T cg01960748 chr1:24522592 NA -0.44 -5.01 -0.41 1.87e-6 Psoriasis vulgaris; TGCT cis rs3782455 1.000 rs75596675 chr12:114401944 A/G cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs56399783 0.901 rs17132624 chr7:2778496 G/A cg19731401 chr7:2775893 GNA12 0.36 5.07 0.41 1.4e-6 Childhood ear infection; TGCT cis rs6671200 0.541 rs7555339 chr1:95691579 G/A cg06440946 chr1:95699313 RWDD3 -0.62 -5.34 -0.43 4.22e-7 Stearic acid (18:0) levels; TGCT cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs3749237 0.964 rs13084243 chr3:49821878 G/C cg03060546 chr3:49711283 APEH 0.73 7.58 0.56 7.07e-12 Resting heart rate; TGCT cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg23205692 chr1:25664452 TMEM50A 0.5 5.17 0.42 9.02e-7 Erythrocyte sedimentation rate; TGCT cis rs6088590 1.000 rs6088607 chr20:33378733 C/T cg06115741 chr20:33292138 TP53INP2 0.66 5.51 0.44 2.01e-7 Coronary artery disease; TGCT cis rs2455799 0.614 rs2121735 chr3:15871201 C/G cg12172478 chr3:16357591 RFTN1 -0.29 -4.48 -0.37 1.7e-5 Mean platelet volume; TGCT cis rs1062177 0.826 rs2915822 chr5:151130901 G/T cg12924095 chr5:151150029 G3BP1 -0.34 -4.93 -0.4 2.62e-6 Preschool internalizing problems; TGCT cis rs1475911 0.708 rs66994219 chr21:43521647 G/A cg14562523 chr21:43528734 C21orf128;UMODL1 -0.27 -5.2 -0.42 7.81e-7 IgG glycosylation; TGCT cis rs6089829 0.925 rs2277767 chr20:61666937 G/A cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs236907 0.859 rs2232819 chr1:171755182 G/A cg20598894 chr1:171756153 METTL13 -0.2 -4.54 -0.38 1.31e-5 Mean platelet volume; TGCT cis rs7666738 0.924 rs13124368 chr4:99039615 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.520 rs7572660 chr2:99788582 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 1.12 15.78 0.82 1.91e-31 Chronic sinus infection; TGCT cis rs2046867 0.644 rs56947804 chr3:72788435 T/C cg25664220 chr3:72788482 NA -0.56 -7.17 -0.54 6.04e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9368481 0.700 rs6911401 chr6:26913214 C/G cg02458000 chr6:26745757 NA 0.6 5.28 0.43 5.6e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9911578 1.000 rs9904879 chr17:56864422 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7824557 0.591 rs2736283 chr8:11225910 A/G cg21775007 chr8:11205619 TDH -0.74 -7.67 -0.57 4.37e-12 Retinal vascular caliber; TGCT cis rs367943 1.000 rs348958 chr5:112821137 G/A cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs12477438 0.765 rs62156363 chr2:99693324 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs28595532 1.000 rs41455648 chr4:119718030 A/G cg21605333 chr4:119757512 SEC24D 1.38 8.0 0.58 7.43e-13 Cannabis dependence symptom count; TGCT cis rs2463822 0.844 rs2513737 chr11:62119495 G/C cg23876832 chr11:62092739 NA 0.63 4.68 0.39 7.29e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9733 0.596 rs11807058 chr1:150640475 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs2046867 0.908 rs62251636 chr3:72792650 A/G cg25664220 chr3:72788482 NA -0.56 -7.15 -0.54 6.59e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4862750 0.872 rs6821507 chr4:187876829 G/T cg03452623 chr4:187889614 NA 0.34 5.19 0.42 8.44e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs506338 0.517 rs530252 chr11:64443465 T/C cg19395706 chr11:64412079 NRXN2 0.5 6.05 0.48 1.58e-8 Body mass index;Urate levels; TGCT cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg04352962 chr1:209979756 IRF6 0.64 4.89 0.4 3.12e-6 Cleft lip with or without cleft palate; TGCT cis rs6087990 0.735 rs2424922 chr20:31386449 T/C cg13636640 chr20:31349939 DNMT3B 0.95 12.3 0.74 3.25e-23 Ulcerative colitis; TGCT cis rs6750047 0.781 rs4670809 chr2:38277364 A/C cg07380506 chr2:38303506 CYP1B1 0.55 4.79 0.4 4.7e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs929354 0.742 rs2006844 chr7:157002851 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.77 -0.62 1.19e-14 Body mass index; TGCT cis rs9611565 0.592 rs5996038 chr22:41965300 T/C cg13695892 chr22:41940480 POLR3H -0.87 -8.17 -0.59 2.95e-13 Vitiligo; TGCT cis rs4713118 0.662 rs9380045 chr6:28025279 A/G cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs986417 0.892 rs74060153 chr14:60794488 T/A cg27398547 chr14:60952738 C14orf39 -1.47 -6.28 -0.49 5.17e-9 Gut microbiota (bacterial taxa); TGCT cis rs10789285 0.650 rs2245330 chr1:69690808 G/A ch.1.69469992R chr1:69697404 NA 0.31 4.54 0.38 1.32e-5 Psoriasis; TGCT cis rs9913156 0.517 rs8065068 chr17:4611453 A/T cg00122941 chr17:4613640 ARRB2 0.83 7.26 0.55 3.77e-11 Lymphocyte counts; TGCT cis rs10193935 0.901 rs1496329 chr2:42688797 T/C cg27598129 chr2:42591480 NA 0.39 5.36 0.43 3.85e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.744 rs11168870 chr12:37973333 A/G cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs6815814 0.861 rs28393318 chr4:38784267 A/G cg02016764 chr4:38805732 TLR1 -0.28 -4.52 -0.38 1.41e-5 Breast cancer; TGCT cis rs941408 1.000 rs4807332 chr19:2793289 T/C cg06609049 chr19:2785107 THOP1 0.79 7.79 0.57 2.36e-12 Total cholesterol levels; TGCT cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg04944784 chr2:26401820 FAM59B -0.77 -6.37 -0.5 3.27e-9 Gut microbiome composition (summer); TGCT cis rs7617773 0.817 rs6796490 chr3:48237104 A/C cg11946769 chr3:48343235 NME6 0.76 7.23 0.54 4.42e-11 Coronary artery disease; TGCT cis rs8037137 0.915 rs79253100 chr15:91551876 C/T cg22570213 chr15:91497863 RCCD1 0.51 4.69 0.39 6.96e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs4819052 0.819 rs13046807 chr21:46672286 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.82 7.39 0.55 1.85e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6964587 0.967 rs58673519 chr7:91823887 T/G cg17063962 chr7:91808500 NA 0.91 9.8 0.66 3.82e-17 Breast cancer; TGCT cis rs4819052 0.851 rs13050359 chr21:46672671 T/G cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12762955 0.507 rs7070724 chr10:1040138 C/T cg18964960 chr10:1102726 WDR37 -0.72 -6.21 -0.49 7.49e-9 Response to angiotensin II receptor blocker therapy; TGCT trans rs324780 0.504 rs1387939 chr12:83912829 T/G cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.29e-10 Vertical cup-disc ratio; TGCT trans rs57221529 0.766 rs12521051 chr5:560440 A/G cg25482853 chr8:67687455 SGK3 -1.18 -10.06 -0.67 9.09e-18 Lung disease severity in cystic fibrosis; TGCT cis rs28595532 1.000 rs115004746 chr4:119642137 C/T cg21605333 chr4:119757512 SEC24D 1.36 7.4 0.55 1.81e-11 Cannabis dependence symptom count; TGCT cis rs3849570 1.000 rs9818006 chr3:81828230 A/C cg07356753 chr3:81810745 GBE1 -0.68 -5.77 -0.46 5.87e-8 Waist circumference;Body mass index; TGCT cis rs73001065 0.551 rs56397647 chr19:19642795 C/T cg03709012 chr19:19516395 GATAD2A 0.93 4.98 0.41 2.1e-6 LDL cholesterol; TGCT cis rs2721173 0.619 rs997258 chr8:145903077 C/A cg15857475 chr8:145742913 RECQL4;LRRC14 -0.93 -9.9 -0.66 2.19e-17 Educational attainment;Cognitive ability (multi-trait analysis);Intelligence (multi-trait analysis); TGCT cis rs2334880 0.678 rs12922597 chr16:71452393 T/C cg06353428 chr16:71660113 MARVELD3 -1.0 -6.72 -0.52 5.97e-10 Malaria; TGCT cis rs7044106 0.762 rs4837789 chr9:123426256 G/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.56 0.38 1.21e-5 Hip circumference adjusted for BMI; TGCT cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg21724239 chr8:58056113 NA 0.38 5.18 0.42 8.82e-7 Developmental language disorder (linguistic errors); TGCT cis rs9650657 0.707 rs10097283 chr8:10659406 G/C cg27411982 chr8:10470053 RP1L1 -0.23 -5.11 -0.42 1.18e-6 Neuroticism; TGCT cis rs6952808 0.717 rs10950422 chr7:1926577 T/C cg22963979 chr7:1858916 MAD1L1 -0.37 -5.67 -0.45 9.59e-8 Bipolar disorder and schizophrenia; TGCT cis rs9818758 0.545 rs9853352 chr3:49813258 C/T cg00383909 chr3:49044727 WDR6 -1.31 -6.76 -0.52 4.72e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs265548 0.595 rs265543 chr19:17904260 T/G cg03316864 chr19:17906309 B3GNT3 0.43 5.0 0.41 1.88e-6 Tumor biomarkers; TGCT cis rs7666738 0.830 rs10019087 chr4:99030211 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6504950 0.705 rs17745123 chr17:52988232 G/T cg07707039 chr17:53042137 COX11 0.28 4.66 0.39 8.03e-6 Breast cancer; TGCT cis rs6815814 0.950 rs5743580 chr4:38804405 C/T cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs6121246 0.567 rs6088796 chr20:30213229 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT trans rs28595532 0.623 rs17516540 chr4:119278443 A/G cg26518628 chr1:97050305 NA -0.6 -7.07 -0.54 1.01e-10 Cannabis dependence symptom count; TGCT cis rs9868809 0.881 rs2276852 chr3:48666923 A/G cg00383909 chr3:49044727 WDR6 0.83 4.64 0.38 8.57e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9899728 0.572 rs9915968 chr17:73059616 G/C cg27626185 chr17:73056755 KCTD2 -0.46 -4.49 -0.37 1.59e-5 Alzheimer's disease or small vessel stroke; TGCT cis rs185694 1.000 rs653251 chr13:30894542 C/T cg07600127 chr13:30881527 KATNAL1 -0.79 -6.56 -0.51 1.34e-9 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs950776 0.545 rs34275594 chr15:78981282 A/C cg21242079 chr15:79101063 ADAMTS7 -0.31 -5.06 -0.41 1.48e-6 Sudden cardiac arrest; TGCT cis rs727563 0.594 rs132807 chr22:42071584 T/C cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10833905 0.680 rs10833893 chr11:23027431 T/G cg06387204 chr11:22647648 FANCF -0.55 -5.07 -0.41 1.44e-6 Sudden cardiac arrest; TGCT cis rs68170813 0.559 rs10953532 chr7:106881808 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs617219 0.574 rs7732681 chr5:78595246 C/T cg09550809 chr5:78407562 BHMT -0.34 -4.58 -0.38 1.11e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10479542 0.929 rs7718673 chr5:178980009 C/T cg00080972 chr5:178986291 RUFY1 -0.43 -4.92 -0.4 2.75e-6 Lung cancer; TGCT cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs2880765 0.835 rs6496027 chr15:86049988 C/T cg13263323 chr15:86062960 AKAP13 -0.23 -4.96 -0.41 2.28e-6 Coronary artery disease; TGCT cis rs7043114 0.563 rs10820986 chr9:95312961 T/G cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -5.26 -0.43 6.07e-7 Height; TGCT cis rs7607369 0.714 rs4674332 chr2:219604326 C/T cg02176678 chr2:219576539 TTLL4 0.5 6.61 0.51 1.04e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg22166914 chr1:53195759 ZYG11B -0.35 -5.81 -0.46 4.89e-8 Monocyte count; TGCT cis rs1322512 1.000 rs2758812 chr6:152965908 C/T cg03415253 chr6:152958462 SYNE1 -0.5 -4.53 -0.38 1.38e-5 Tonometry; TGCT cis rs61897795 0.628 rs93923 chr11:61613745 C/T cg19610905 chr11:61596333 FADS2 -0.81 -6.26 -0.49 5.64e-9 Neutrophil count;Sum basophil neutrophil counts; TGCT cis rs4821897 0.514 rs739141 chr22:39824450 A/G cg11247378 chr22:39784982 NA 0.66 8.79 0.62 1.04e-14 IgG glycosylation; TGCT cis rs765787 0.530 rs4775835 chr15:45537553 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg21724239 chr8:58056113 NA -0.42 -5.04 -0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs4819052 0.851 rs7276828 chr21:46695039 T/G cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs8073515 chr17:61795328 A/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs428668 0.681 rs430961 chr5:150700559 C/G cg11125805 chr5:150678162 SLC36A3 0.26 5.9 0.47 3.19e-8 Skin aging (microtopography measurement); TGCT cis rs10927875 0.691 rs1048261 chr1:16340951 A/T cg22431228 chr1:16359049 CLCNKA -0.25 -4.77 -0.39 5.1e-6 Dilated cardiomyopathy; TGCT cis rs806215 1.000 rs806215 chr7:127237312 T/C cg00893242 chr7:127291580 SND1 -0.42 -4.46 -0.37 1.84e-5 Type 2 diabetes; TGCT cis rs7772486 0.875 rs1331637 chr6:146337087 T/C cg05347473 chr6:146136440 FBXO30 0.56 5.29 0.43 5.34e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs367615 0.660 rs4632850 chr5:108832883 C/G cg17395555 chr5:108820864 NA 0.31 5.9 0.47 3.17e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs651907 0.535 rs11707250 chr3:101509371 A/T cg11279151 chr3:101281821 RG9MTD1 0.31 6.52 0.51 1.56e-9 Colorectal cancer; TGCT cis rs597539 0.652 rs559032 chr11:68710847 G/T cg06112835 chr11:68658793 MRPL21 0.46 7.79 0.57 2.3e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs12579753 0.912 rs4417392 chr12:82158722 C/A cg21231944 chr12:82153410 PPFIA2 -0.34 -4.63 -0.38 8.95e-6 Resting heart rate; TGCT cis rs2637266 0.967 rs4979898 chr10:78355672 G/A cg18941641 chr10:78392320 NA 0.4 5.01 0.41 1.81e-6 Pulmonary function; TGCT cis rs7811142 0.830 rs7792959 chr7:99972403 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.9 7.25 0.55 3.93e-11 Platelet count; TGCT cis rs4680 0.737 rs3810595 chr22:19949644 G/C cg22546130 chr22:19950026 COMT -0.35 -5.26 -0.43 6.21e-7 Blood metabolite levels; TGCT cis rs587847 0.597 rs10162992 chr15:37763299 T/C cg00216138 chr15:37171175 LOC145845 0.31 4.55 0.38 1.26e-5 Intraocular pressure; TGCT cis rs9739070 1 rs9739070 chr12:123771032 A/G cg00376283 chr12:123451042 ABCB9 0.7 4.78 0.39 4.84e-6 Allergy; TGCT cis rs2115630 0.641 rs11073613 chr15:85185893 G/A cg11189052 chr15:85197271 WDR73 -0.73 -7.39 -0.55 1.9e-11 P wave terminal force; TGCT cis rs7777484 0.534 rs2258709 chr7:2832365 C/T cg25467336 chr7:2757616 NA 0.24 4.63 0.38 8.93e-6 Height; TGCT cis rs7829975 0.688 rs7817376 chr8:8380530 C/T cg08975724 chr8:8085496 FLJ10661 -0.64 -6.03 -0.48 1.77e-8 Mood instability; TGCT cis rs9916302 0.904 rs11078915 chr17:37715426 T/C cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs7834745 0.553 rs1485286 chr8:119950668 C/T cg17171407 chr8:119960777 TNFRSF11B -0.29 -4.55 -0.38 1.24e-5 Eosinophil counts;Sum eosinophil basophil counts; TGCT cis rs3733585 0.673 rs10018204 chr4:9964570 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4819052 0.851 rs2838855 chr21:46680566 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.84 -7.5 -0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs2692947 0.666 rs10183151 chr2:96774786 T/G cg05933789 chr2:97190408 NA -0.17 -4.95 -0.41 2.34e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7727544 0.545 rs10074490 chr5:131340032 C/T cg24060327 chr5:131705240 SLC22A5 -0.54 -4.68 -0.39 7.27e-6 Blood metabolite levels; TGCT cis rs9354352 0.935 rs9354354 chr6:66699333 A/G cg07460842 chr6:66804631 NA -0.64 -6.64 -0.51 8.69e-10 Initial pursuit acceleration in psychotic disorders; TGCT cis rs875971 0.660 rs7807944 chr7:66087195 C/G cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs6484504 0.532 rs7117286 chr11:31283810 T/A cg14844989 chr11:31128820 NA -0.24 -4.66 -0.39 7.87e-6 Red blood cell count; TGCT cis rs9902453 0.934 rs12453172 chr17:28441590 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.55 0.51 1.4e-9 Coffee consumption (cups per day); TGCT cis rs1218582 0.688 rs58629129 chr1:154910930 T/C cg24250549 chr1:154909240 PMVK 0.47 4.49 0.37 1.58e-5 Prostate cancer; TGCT cis rs6748734 0.843 rs6749674 chr2:241834501 G/C cg04034577 chr2:241836375 C2orf54 -0.4 -6.32 -0.49 4.22e-9 Urinary metabolites; TGCT cis rs7937612 1.000 rs7937612 chr11:120278688 T/C cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.44 -0.37 1.96e-5 Intraocular pressure; TGCT cis rs7917772 0.503 rs7096072 chr10:104299976 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11676348 0.818 rs6436033 chr2:218983763 A/G cg00012203 chr2:219082015 ARPC2 -0.52 -4.98 -0.41 2.08e-6 Ulcerative colitis; TGCT cis rs3749237 0.595 rs4855861 chr3:49525962 G/T cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs8072100 0.701 rs8078309 chr17:45774072 T/C cg08085267 chr17:45401833 C17orf57 -0.43 -4.82 -0.4 4.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs35306767 0.903 rs12260800 chr10:927933 T/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs968451 1.000 rs62228376 chr22:39701097 G/C cg17798944 chr22:39715225 SNORD43;RPL3 0.87 7.73 0.57 3.17e-12 Primary biliary cholangitis; TGCT cis rs3733585 0.673 rs4627861 chr4:9954238 T/G cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11673344 0.504 rs10403975 chr19:37573074 A/G cg08039142 chr19:36980659 ZNF566 0.5 4.6 0.38 1.01e-5 Obesity-related traits; TGCT cis rs797680 0.856 rs9432681 chr1:93761896 A/G cg17826107 chr1:92977322 EVI5 0.23 5.1 0.42 1.24e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6484504 0.532 rs2616799 chr11:31319044 T/C cg26647111 chr11:31128758 NA 0.32 4.64 0.38 8.82e-6 Red blood cell count; TGCT cis rs12497850 0.864 rs6779394 chr3:49157771 G/A cg07636037 chr3:49044803 WDR6 0.95 9.94 0.67 1.78e-17 Parkinson's disease; TGCT cis rs910316 0.934 rs4903278 chr14:75535019 C/A cg08847533 chr14:75593920 NEK9 0.95 10.3 0.68 2.36e-18 Height; TGCT trans rs561341 1.000 rs4795667 chr17:30244443 T/C cg20587970 chr11:113659929 NA -0.97 -11.47 -0.72 3.31e-21 Hip circumference adjusted for BMI; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg09033563 chr22:24373618 LOC391322 -0.52 -5.06 -0.41 1.46e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6693567 0.565 rs3754214 chr1:150478623 T/C cg09579323 chr1:150459698 TARS2 0.52 4.63 0.38 9.26e-6 Migraine; TGCT cis rs9653442 0.545 rs11123813 chr2:100765692 C/T cg22139774 chr2:100720529 AFF3 -0.35 -5.58 -0.45 1.45e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs875971 0.929 rs12673810 chr7:65923853 T/A cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg26116260 chr4:7069785 GRPEL1 1.06 10.07 0.67 8.61e-18 Monocyte percentage of white cells; TGCT cis rs832540 0.931 rs1466008 chr5:56213406 G/C cg12311346 chr5:56204834 C5orf35 -0.47 -4.97 -0.41 2.15e-6 Coronary artery disease; TGCT cis rs2013441 1.000 rs4924809 chr17:20044673 C/T cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs6817645 chr4:99016054 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 0.837 rs208471 chr6:66916749 A/C cg07460842 chr6:66804631 NA -0.9 -9.16 -0.64 1.34e-15 Exhaled nitric oxide output; TGCT cis rs36051895 0.559 rs12342390 chr9:5211297 G/A cg02405213 chr9:5042618 JAK2 -0.65 -8.06 -0.59 5.34e-13 Pediatric autoimmune diseases; TGCT cis rs941898 0.625 rs6575763 chr14:100571762 A/G cg19757573 chr14:101506246 MIR654;MIR376B;MIR376A2;MIR300;MIR376A1 0.15 4.67 0.39 7.66e-6 White matter hyperintensity burden; TGCT cis rs6866344 0.570 rs1132338 chr5:178139442 T/G cg03877680 chr5:178157825 ZNF354A 0.77 6.79 0.52 4.12e-10 Neutrophil percentage of white cells; TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs8016982 0.633 rs7160342 chr14:81713427 G/C cg01989461 chr14:81687754 GTF2A1 0.76 7.5 0.56 1.09e-11 Schizophrenia; TGCT cis rs9303401 0.592 rs12936771 chr17:56725052 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs3849570 0.533 rs6548784 chr3:81995889 G/A cg07356753 chr3:81810745 GBE1 -0.56 -4.67 -0.39 7.73e-6 Waist circumference;Body mass index; TGCT cis rs1406084 0.526 rs1373584 chr2:154723354 G/C cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT trans rs6089829 0.962 rs2277769 chr20:61666805 C/T cg17470723 chr8:74884337 TCEB1 0.74 7.16 0.54 6.16e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs72781680 0.756 rs2712059 chr2:24020539 T/C cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs3806843 0.966 rs6579965 chr5:140168811 T/G cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs2836974 0.965 rs2836965 chr21:40633631 C/G cg11644478 chr21:40555479 PSMG1 -0.95 -10.52 -0.69 6.69e-19 Cognitive function; TGCT cis rs10501293 1.000 rs10838010 chr11:43122962 T/C cg03447554 chr11:43094025 NA -0.49 -6.73 -0.52 5.72e-10 Cognitive performance; TGCT trans rs3822625 0.541 rs76679228 chr5:56199511 C/T cg25190722 chr1:3801660 DFFB 0.56 6.67 0.51 7.53e-10 Breast cancer (early onset); TGCT cis rs7772486 0.790 rs2265919 chr6:146221753 A/G cg05347473 chr6:146136440 FBXO30 0.52 5.0 0.41 1.89e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4808199 0.895 rs10421505 chr19:19459554 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.71 5.73 0.46 7.17e-8 Nonalcoholic fatty liver disease; TGCT cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.52 5.49 0.44 2.14e-7 Menopause (age at onset); TGCT cis rs7954584 0.567 rs11043251 chr12:122373279 C/T cg22618164 chr12:122356400 WDR66 0.69 6.52 0.51 1.6e-9 Mean corpuscular volume; TGCT cis rs6912958 0.728 rs7773906 chr6:88251869 T/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs954108 0.522 rs7983818 chr13:29383182 A/C cg11788234 chr13:29393811 NA -0.49 -6.84 -0.52 3.26e-10 Obesity-related traits; TGCT cis rs4788570 0.511 rs4788830 chr16:71732267 A/G cg06353428 chr16:71660113 MARVELD3 1.57 13.04 0.76 5.38e-25 Intelligence (multi-trait analysis); TGCT trans rs28735056 0.584 rs35614280 chr18:77636679 C/G cg05926928 chr17:57297772 GDPD1 0.86 9.32 0.64 5.69e-16 Schizophrenia; TGCT cis rs3015497 1.000 rs3015497 chr14:51113398 T/C cg04730355 chr14:51134070 SAV1 -0.54 -4.74 -0.39 5.8e-6 Mean platelet volume; TGCT cis rs2576037 0.544 rs629097 chr18:44378097 T/C cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.7 -0.39 6.77e-6 Personality dimensions; TGCT cis rs9359856 0.510 rs2768936 chr6:90441851 A/G cg13799429 chr6:90582589 CASP8AP2 -0.45 -4.66 -0.39 7.9e-6 Bipolar disorder; TGCT cis rs12620999 1.000 rs13004252 chr2:238035408 C/A cg23555395 chr2:238036564 NA -0.29 -4.69 -0.39 7.03e-6 Systemic lupus erythematosus; TGCT cis rs2455799 0.517 rs1447647 chr3:15933465 C/T cg12172478 chr3:16357591 RFTN1 -0.33 -4.78 -0.39 4.86e-6 Mean platelet volume; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.37 4.86 0.4 3.54e-6 Lymphocyte counts; TGCT cis rs2721195 0.967 rs748195 chr8:145682514 T/C cg15320075 chr8:145703422 NA 0.71 7.34 0.55 2.45e-11 Age at first birth; TGCT cis rs7666738 0.830 rs10012003 chr4:99064881 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.86 0.47 3.86e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2075371 1.000 rs2598294 chr7:133991690 C/T cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs9814567 0.806 rs9839705 chr3:134323819 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.77 -7.21 -0.54 4.87e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs597539 0.652 rs579136 chr11:68637476 C/G cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs5769765 0.773 rs9616206 chr22:50310847 G/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.22 -12.49 -0.75 1.11e-23 Schizophrenia; TGCT cis rs2456568 0.548 rs10466335 chr11:93663820 G/C cg26875233 chr11:93583750 C11orf90 -0.41 -5.0 -0.41 1.87e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7089973 0.668 rs7077148 chr10:116644896 A/G cg03647239 chr10:116582469 FAM160B1 0.58 5.42 0.44 2.94e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs72945132 0.882 rs7945389 chr11:70158876 C/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs6121246 0.567 rs6120815 chr20:30184866 T/C cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs2439831 0.850 rs544122 chr15:43775732 A/T cg02155558 chr15:43621948 ADAL;LCMT2 0.94 6.52 0.51 1.58e-9 Lung cancer in ever smokers; TGCT cis rs6496667 0.558 rs61653706 chr15:91076654 G/A cg22089800 chr15:90895588 ZNF774 0.71 5.45 0.44 2.63e-7 Rheumatoid arthritis; TGCT cis rs2066819 1.000 rs76466034 chr12:56719450 G/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.520 rs2964969 chr2:99782811 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs1008375 0.931 rs7672369 chr4:17604825 A/G cg16339924 chr4:17578868 LAP3 0.74 5.92 0.47 3e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1218582 0.774 rs2335409 chr1:154916106 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.67 -6.61 -0.51 1.01e-9 Prostate cancer; TGCT cis rs3087591 1.000 rs2854332 chr17:29712378 A/T cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.26 -0.55 3.66e-11 Hip circumference; TGCT cis rs4455778 0.580 rs6583509 chr7:49122419 A/G cg26309511 chr7:48887640 NA -0.51 -6.64 -0.51 8.83e-10 Lung cancer in never smokers; TGCT cis rs986417 1.000 rs1116853 chr14:60917476 A/G cg27398547 chr14:60952738 C14orf39 1.37 8.92 0.63 5.07e-15 Gut microbiota (bacterial taxa); TGCT cis rs9646954 0.542 rs4149513 chr2:101022726 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.76 0.39 5.2e-6 Intelligence (multi-trait analysis); TGCT cis rs7412746 0.634 rs3754212 chr1:150738200 A/G cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs3824867 0.879 rs10769267 chr11:47460098 C/T cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs9894429 0.646 rs7406828 chr17:79619226 A/G cg18240062 chr17:79603768 NPLOC4 -0.57 -5.05 -0.41 1.53e-6 Eye color traits; TGCT cis rs4919044 0.808 rs835280 chr10:94811786 A/G cg05127821 chr10:94822908 CYP26C1 -0.75 -4.85 -0.4 3.66e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs35951881 chr4:98999474 A/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2338224 1.000 rs4703886 chr5:71745985 C/T cg01187920 chr5:71015162 CARTPT -0.53 -4.57 -0.38 1.15e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT trans rs621559 0.535 rs678101 chr1:43671495 T/C cg19324027 chr2:74699582 MRPL53 0.87 6.75 0.52 5.12e-10 Telomere length; TGCT cis rs60871478 1.000 rs4397290 chr7:828493 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.47 -4.48 -0.37 1.7e-5 Cerebrospinal P-tau181p levels; TGCT cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.11 -0.63 1.82e-15 Bipolar disorder; TGCT cis rs5769707 0.967 rs12485195 chr22:50053871 G/A cg05373962 chr22:49881684 NA -0.32 -6.66 -0.51 7.86e-10 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7267979 0.668 rs2387977 chr20:25599776 C/T cg14121845 chr20:25566513 NINL -0.45 -5.08 -0.41 1.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg25767906 chr1:53392781 SCP2 -0.51 -6.22 -0.49 6.83e-9 Monocyte count; TGCT cis rs11209002 0.614 rs4655673 chr1:67555018 T/C cg02640540 chr1:67518911 SLC35D1 0.55 4.63 0.38 8.99e-6 Crohn's disease; TGCT cis rs12908161 0.920 rs35758837 chr15:85311382 C/T cg17173187 chr15:85201210 NMB 0.57 6.4 0.5 2.89e-9 Schizophrenia; TGCT cis rs7100689 0.753 rs1572816 chr10:82137600 A/G cg01528321 chr10:82214614 TSPAN14 0.88 8.51 0.61 4.73e-14 Post bronchodilator FEV1; TGCT cis rs7843479 1.000 rs67385415 chr8:21853733 T/C cg17168535 chr8:21777572 XPO7 0.63 5.71 0.46 7.71e-8 Mean corpuscular volume; TGCT cis rs3749237 0.595 rs6797765 chr3:49423976 A/G cg02487422 chr3:49467188 NICN1 0.59 6.01 0.47 1.92e-8 Resting heart rate; TGCT cis rs7953249 0.807 rs7970695 chr12:121423376 G/A cg02403541 chr12:121454288 C12orf43 -0.53 -4.56 -0.38 1.23e-5 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs4889855 0.530 rs4889863 chr17:78550468 C/T cg16591659 chr17:78472290 NA -0.28 -4.45 -0.37 1.89e-5 Fractional excretion of uric acid; TGCT cis rs4788570 0.566 rs72791974 chr16:71478574 A/T cg06353428 chr16:71660113 MARVELD3 -1.31 -7.67 -0.57 4.46e-12 Intelligence (multi-trait analysis); TGCT cis rs56104184 0.830 rs17272658 chr19:49355405 C/T cg21252483 chr19:49399788 TULP2 -0.41 -5.21 -0.42 7.47e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4566357 0.539 rs10933164 chr2:227860671 A/G cg11843606 chr2:227700838 RHBDD1 -0.76 -6.43 -0.5 2.49e-9 Coronary artery disease; TGCT cis rs12220238 1.000 rs10824083 chr10:75911342 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.53 -0.61 4.23e-14 Platelet count; TGCT cis rs711830 0.931 rs6755766 chr2:177043205 T/C cg13092806 chr2:177043255 NA 0.77 6.12 0.48 1.14e-8 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs9527 0.590 rs10883830 chr10:104851285 G/A cg04362960 chr10:104952993 NT5C2 0.67 5.76 0.46 6.28e-8 Arsenic metabolism; TGCT trans rs7726839 0.526 rs11960158 chr5:568665 C/T cg25482853 chr8:67687455 SGK3 1.1 8.74 0.62 1.34e-14 Obesity-related traits; TGCT cis rs6725041 0.792 rs1533769 chr2:213089956 A/C cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs3733585 0.699 rs7676733 chr4:9966956 G/A cg11266682 chr4:10021025 SLC2A9 -0.59 -7.87 -0.58 1.53e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs682748 0.755 rs2402349 chr5:17122819 T/C cg23987134 chr5:17158319 LOC285696 -0.21 -4.98 -0.41 2.1e-6 Hippocampal atrophy; TGCT cis rs1348850 0.567 rs12994392 chr2:178536640 A/G cg22681709 chr2:178499509 PDE11A -0.49 -6.15 -0.48 9.86e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7119 0.717 rs11635567 chr15:77819515 A/G cg27398640 chr15:77910606 LINGO1 -0.26 -4.66 -0.39 7.98e-6 Type 2 diabetes; TGCT cis rs933688 0.938 rs6869048 chr5:90664322 G/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 10.13 0.67 6.16e-18 Smoking behavior; TGCT cis rs16854884 0.741 rs55909524 chr3:143794734 T/C cg06585982 chr3:143692056 C3orf58 0.61 4.72 0.39 6.19e-6 Economic and political preferences (feminism/equality); TGCT cis rs11112613 0.713 rs60865625 chr12:105940256 A/C cg03607813 chr12:105948248 NA 0.45 4.98 0.41 2.05e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7666738 0.716 rs28792413 chr4:99083707 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.5 0.44 2.07e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg13342137 chr4:2252803 MXD4 0.17 4.47 0.37 1.71e-5 Obesity-related traits; TGCT cis rs1532993 0.518 rs28838303 chr4:98616189 G/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs9534288 0.912 rs4941540 chr13:46604710 C/T cg15192986 chr13:46630673 CPB2 -0.51 -6.62 -0.51 9.95e-10 Blood protein levels; TGCT cis rs7829975 0.560 rs17154599 chr8:8551418 C/T cg06636001 chr8:8085503 FLJ10661 -0.6 -5.35 -0.43 4.13e-7 Mood instability; TGCT cis rs7542091 0.637 rs9429826 chr1:210052146 G/A cg23283495 chr1:209979779 IRF6 0.54 5.28 0.43 5.66e-7 Monobrow; TGCT cis rs2456568 0.802 rs1395387 chr11:93639307 A/T cg16099599 chr11:93583650 C11orf90 -0.4 -4.99 -0.41 1.98e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2594989 0.943 rs9878389 chr3:11457099 T/G cg00170343 chr3:11313890 ATG7 0.67 5.12 0.42 1.13e-6 Circulating chemerin levels; TGCT cis rs10479542 0.766 rs7733389 chr5:178974997 C/T cg09060608 chr5:178986726 RUFY1 0.49 5.67 0.45 9.29e-8 Lung cancer; TGCT cis rs9326248 1.000 rs10790175 chr11:117034729 A/G cg11861562 chr11:117069780 TAGLN 0.28 4.64 0.38 8.74e-6 Blood protein levels; TGCT cis rs208520 0.955 rs12204033 chr6:67001525 T/C cg07460842 chr6:66804631 NA 0.69 5.83 0.46 4.48e-8 Exhaled nitric oxide output; TGCT cis rs6582630 0.572 rs1969363 chr12:38514872 A/G cg26384229 chr12:38710491 ALG10B 0.57 5.01 0.41 1.85e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs12477438 0.765 rs1054042 chr2:99614396 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.79 -7.94 -0.58 1.06e-12 Chronic sinus infection; TGCT cis rs877282 0.853 rs11595507 chr10:756703 C/T cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg15462221 chr8:8086144 FLJ10661 -0.54 -4.88 -0.4 3.22e-6 Systolic blood pressure; TGCT cis rs1322512 0.760 rs2038615 chr6:152927267 C/T cg03415253 chr6:152958462 SYNE1 0.5 4.93 0.4 2.61e-6 Tonometry; TGCT trans rs12339966 0.615 rs62529419 chr9:11336618 G/T cg03488587 chr11:64876988 C11orf2 0.32 7.0 0.53 1.42e-10 Systolic blood pressure; TGCT cis rs2180341 1.000 rs9388561 chr6:127634921 C/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs9322193 0.884 rs10782312 chr6:149943805 G/T cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs2242116 0.727 rs7635480 chr3:46968227 T/C cg02527881 chr3:46936655 PTH1R -0.29 -5.44 -0.44 2.77e-7 Birth weight; TGCT cis rs73198271 0.740 rs28402110 chr8:8647249 C/A cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1023500 0.505 rs134885 chr22:42673811 C/G cg05082376 chr22:42548792 NA -0.21 -4.47 -0.37 1.76e-5 Schizophrenia; TGCT cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg17054783 chr10:134559939 INPP5A 0.24 4.78 0.39 4.95e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3820928 0.935 rs10203363 chr2:227896976 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -4.96 -0.41 2.29e-6 Pulmonary function; TGCT cis rs12477438 0.798 rs4851179 chr2:99568774 G/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.75 -6.57 -0.51 1.27e-9 Chronic sinus infection; TGCT cis rs2456568 0.778 rs7940973 chr11:93682045 C/G cg17595323 chr11:93583763 C11orf90 0.4 5.27 0.43 5.97e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2456568 0.802 rs1574515 chr11:93629643 T/C cg17595323 chr11:93583763 C11orf90 -0.47 -6.49 -0.5 1.85e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4689388 0.926 rs10937718 chr4:6295217 T/C cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9296092 0.538 rs75652975 chr6:33516251 C/T cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.25e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6952808 0.729 rs35797753 chr7:1954914 G/A cg22963979 chr7:1858916 MAD1L1 -0.35 -5.25 -0.43 6.34e-7 Bipolar disorder and schizophrenia; TGCT cis rs9787249 1.000 rs9787249 chr1:40212878 G/A cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs61008539 0.893 rs4721502 chr7:862186 A/G cg00475322 chr7:917719 C7orf20 0.5 6.52 0.51 1.63e-9 Perceived unattractiveness to mosquitoes; TGCT cis rs17076896 0.786 rs7339224 chr13:19934027 C/T cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs1552244 1.000 rs4260416 chr3:10125283 C/T cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs916888 0.821 rs199514 chr17:44856881 G/A cg05721485 chr17:44071124 MAPT -0.25 -4.44 -0.37 1.96e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1355223 0.583 rs1553757 chr11:34867089 G/A cg24088639 chr11:34937564 PDHX;APIP -0.5 -4.51 -0.38 1.45e-5 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs2046867 0.908 rs113001746 chr3:72824260 C/T cg25664220 chr3:72788482 NA -0.53 -6.71 -0.52 6.19e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs17767294 0.708 rs72847343 chr6:27790833 A/G cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg10047753 chr17:41438598 NA 0.97 9.67 0.66 7.94e-17 Menopause (age at onset); TGCT cis rs28595532 0.920 rs17257945 chr4:119666465 T/A cg14228332 chr4:119757509 SEC24D 1.06 5.75 0.46 6.55e-8 Cannabis dependence symptom count; TGCT cis rs9379850 0.730 rs9393738 chr6:26620658 G/A cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.48 -4.59 -0.38 1.06e-5 Intelligence (multi-trait analysis); TGCT cis rs3947 1.000 rs3947 chr8:11702375 G/A cg02840367 chr8:11660030 FDFT1 0.91 6.7 0.52 6.58e-10 Blood protein levels; TGCT cis rs1552244 0.572 rs59074548 chr3:10164347 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.37 -0.43 3.72e-7 Alzheimer's disease; TGCT cis rs12210905 0.610 rs12204953 chr6:27396737 G/A cg08851530 chr6:28072375 NA 1.34 6.07 0.48 1.44e-8 Hip circumference adjusted for BMI; TGCT cis rs12530845 0.945 rs12540273 chr7:135333854 T/G cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs4253772 0.513 rs6008612 chr22:46707907 G/A cg24881330 chr22:46731750 TRMU 0.97 6.37 0.5 3.32e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs3733585 0.753 rs1122141 chr4:9947278 T/C cg00071950 chr4:10020882 SLC2A9 -0.64 -7.92 -0.58 1.18e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs858239 0.730 rs858290 chr7:23248036 A/G cg05407003 chr7:23246146 NA -0.28 -4.54 -0.38 1.29e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs1552244 0.572 rs66514627 chr3:10166632 A/C cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs7223966 1.000 rs3817181 chr17:61776538 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.51 0.38 1.49e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs8051431 0.876 rs1122531 chr16:72012772 C/T cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs7246657 0.525 rs1667351 chr19:37478027 A/T cg18154014 chr19:37997991 ZNF793 0.67 5.37 0.43 3.75e-7 Coronary artery calcification; TGCT cis rs806215 0.547 rs62481385 chr7:127410711 G/A cg11539674 chr7:127291444 SND1 -0.37 -4.72 -0.39 6.35e-6 Type 2 diabetes; TGCT cis rs2836950 0.545 rs2836940 chr21:40588696 T/C cg11890956 chr21:40555474 PSMG1 -0.68 -6.67 -0.51 7.62e-10 Menarche (age at onset); TGCT cis rs17221829 0.673 rs10765225 chr11:89384988 T/C cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs7772486 0.623 rs735535 chr6:146036829 C/T cg23711669 chr6:146136114 FBXO30 -0.89 -10.12 -0.67 6.37e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs6964587 1.000 rs13224513 chr7:91601465 G/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs9467773 0.967 rs7753565 chr6:26560012 A/G cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs11098499 0.865 rs11722183 chr4:120280597 A/C cg09307838 chr4:120376055 NA 0.66 6.56 0.51 1.29e-9 Corneal astigmatism; TGCT cis rs10504229 0.680 rs11777459 chr8:58044241 A/T cg11062466 chr8:58055876 NA 0.34 4.57 0.38 1.16e-5 Developmental language disorder (linguistic errors); TGCT cis rs1670533 0.932 rs2248083 chr4:1052166 A/C cg20887711 chr4:1340912 KIAA1530 0.74 5.84 0.46 4.22e-8 Recombination rate (females); TGCT cis rs74233809 0.901 rs77335224 chr10:104636276 C/T cg05855489 chr10:104503620 C10orf26 0.79 4.56 0.38 1.19e-5 Birth weight; TGCT cis rs10540 1.000 rs61876334 chr11:487201 T/C cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.12e-5 Body mass index; TGCT cis rs2070488 1.000 rs3792527 chr3:38493212 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs6424115 0.771 rs2229586 chr1:24200903 G/C cg15997130 chr1:24165203 NA 0.87 9.52 0.65 1.79e-16 Immature fraction of reticulocytes; TGCT cis rs801193 0.548 rs2659891 chr7:66201114 A/G cg11764359 chr7:65958608 NA 0.54 4.79 0.4 4.68e-6 Aortic root size; TGCT cis rs858239 0.831 rs7796541 chr7:23389073 G/T cg05602783 chr7:23145260 KLHL7 -0.65 -5.8 -0.46 5.13e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg04317338 chr11:64019027 PLCB3 0.7 6.04 0.48 1.69e-8 Mean platelet volume; TGCT cis rs9810089 0.802 rs10935182 chr3:136137422 G/A cg12473912 chr3:136751656 NA 0.35 5.1 0.42 1.26e-6 Gestational age at birth (child effect); TGCT cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs2836950 0.501 rs11702505 chr21:40700614 G/T cg11890956 chr21:40555474 PSMG1 -0.64 -5.97 -0.47 2.38e-8 Menarche (age at onset); TGCT cis rs7845219 0.525 rs10956931 chr8:95930301 A/G cg16049864 chr8:95962084 TP53INP1 -0.44 -4.75 -0.39 5.61e-6 Type 2 diabetes; TGCT cis rs79149102 0.579 rs79916508 chr15:75373721 A/C cg09165964 chr15:75287851 SCAMP5 -1.0 -5.42 -0.44 3.02e-7 Lung cancer; TGCT cis rs10089 1.000 rs13356473 chr5:127478250 T/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.53 0.56 9.3e-12 Ileal carcinoids; TGCT trans rs1814175 0.817 rs4084376 chr11:49831160 T/C cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs6701037 0.566 rs10489326 chr1:175134677 A/G cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs1355223 0.583 rs2915177 chr11:34880266 A/G cg11058730 chr11:34937778 PDHX;APIP 0.8 8.94 0.63 4.49e-15 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs7044106 0.791 rs12554440 chr9:123485333 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.51 5.62 0.45 1.22e-7 Hip circumference adjusted for BMI; TGCT cis rs7394190 0.748 rs11000773 chr10:75534115 G/T cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs854765 0.647 rs854770 chr17:18019048 A/G cg04398451 chr17:18023971 MYO15A -0.39 -6.75 -0.52 5e-10 Total body bone mineral density; TGCT cis rs4455778 0.659 rs9642330 chr7:49032828 A/C cg26309511 chr7:48887640 NA 0.44 5.22 0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs2562456 0.755 rs1879234 chr19:21704479 T/G cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs4688759 0.609 rs113176147 chr3:49534439 G/T cg00383909 chr3:49044727 WDR6 1.47 6.03 0.48 1.75e-8 Blood protein levels; TGCT cis rs259282 0.524 rs1559180 chr19:33127443 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.82 0.46 4.63e-8 Schizophrenia; TGCT cis rs7809950 0.815 rs62482495 chr7:106965009 A/G cg23024343 chr7:107201750 COG5 -0.43 -5.85 -0.47 4.12e-8 Coronary artery disease; TGCT cis rs7572733 0.534 rs1589162 chr2:198782692 A/G cg00792783 chr2:198669748 PLCL1 0.58 5.05 0.41 1.52e-6 Dermatomyositis; TGCT cis rs10089 1.000 rs13357268 chr5:127423051 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.77 7.29 0.55 3.16e-11 Ileal carcinoids; TGCT cis rs4949454 0.542 rs10914457 chr1:32094261 A/C cg13919466 chr1:32135498 COL16A1 0.37 5.1 0.42 1.23e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.546 rs10461174 chr4:98698293 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.78 0.39 4.93e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.935 rs110289 chr6:145865176 C/G cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.679 rs6995378 chr8:58113933 C/T cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs3125734 0.608 rs7094950 chr10:64019744 T/C cg09941381 chr10:64027924 RTKN2 -0.36 -5.49 -0.44 2.19e-7 Rheumatoid arthritis; TGCT cis rs1865760 0.566 rs9348706 chr6:26065481 G/C cg17042849 chr6:26104293 HIST1H4C -0.63 -5.5 -0.44 2.1e-7 Height; TGCT cis rs2016266 0.855 rs930900 chr12:53727545 T/C cg16917193 chr12:54089295 NA 0.64 4.56 0.38 1.23e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs992157 0.798 rs12053514 chr2:219167965 C/T cg00012203 chr2:219082015 ARPC2 -0.82 -8.13 -0.59 3.76e-13 Colorectal cancer; TGCT cis rs769267 0.929 rs2965180 chr19:19491973 T/C cg03709012 chr19:19516395 GATAD2A -0.76 -6.42 -0.5 2.64e-9 Tonsillectomy; TGCT cis rs12477438 0.798 rs12473029 chr2:99637961 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.71 -6.18 -0.49 8.51e-9 Chronic sinus infection; TGCT cis rs9948 0.655 rs61742095 chr2:97366088 T/C cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs10992471 0.603 rs9299405 chr9:95284873 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.59 -5.61 -0.45 1.26e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs611744 0.967 rs660816 chr8:109178048 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs116095464 0.558 rs6878087 chr5:223117 C/T cg12570787 chr5:219185 SDHA;CCDC127 -0.73 -5.16 -0.42 9.52e-7 Breast cancer; TGCT cis rs36051895 0.622 rs10974952 chr9:5079828 A/T cg02405213 chr9:5042618 JAK2 -0.78 -10.08 -0.67 8.17e-18 Pediatric autoimmune diseases; TGCT cis rs739496 0.527 rs3752632 chr12:112376297 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs9303401 0.659 rs12935851 chr17:56600244 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs10510102 0.872 rs12265542 chr10:123728255 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs4494114 1.000 rs880303 chr1:39340282 C/T cg25970120 chr1:39325951 RRAGC -0.6 -6.23 -0.49 6.58e-9 Blood protein levels; TGCT cis rs4927850 1.000 rs7627868 chr3:195753473 A/T cg02975922 chr3:195473998 MUC4 -0.24 -5.47 -0.44 2.4e-7 Pancreatic cancer; TGCT cis rs7617773 0.817 rs11709691 chr3:48303669 A/G cg11946769 chr3:48343235 NME6 0.76 6.64 0.51 8.76e-10 Coronary artery disease; TGCT cis rs7804356 0.651 rs7803699 chr7:26814173 T/C cg03456212 chr7:26904342 SKAP2 -0.54 -4.6 -0.38 1.04e-5 Type 1 diabetes; TGCT cis rs42648 0.935 rs7793743 chr7:90031619 G/A cg25739043 chr7:89950458 NA 0.62 5.99 0.47 2.08e-8 Homocysteine levels; TGCT cis rs7267979 1.000 rs7267979 chr20:25298087 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9916302 0.706 rs4795385 chr17:37733148 A/G cg07936489 chr17:37558343 FBXL20 0.84 6.16 0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs58688157 0.960 rs1055382 chr11:612182 T/C cg16486109 chr11:613632 IRF7 0.35 5.18 0.42 8.82e-7 Systemic lupus erythematosus; TGCT cis rs7666738 0.830 rs1593570 chr4:99017058 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8017423 0.740 rs7152196 chr14:90703900 G/T cg04374321 chr14:90722782 PSMC1 0.77 8.04 0.59 6.19e-13 Mortality in heart failure; TGCT cis rs7178572 0.568 rs7167794 chr15:77635875 T/C cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs4629710 0.568 rs9492880 chr6:131565962 G/T cg12606694 chr6:131520996 AKAP7 0.38 4.44 0.37 1.97e-5 Multiple myeloma (IgH translocation); TGCT cis rs35883536 0.626 rs10493933 chr1:101111282 A/G cg06223162 chr1:101003688 GPR88 -0.38 -6.71 -0.52 6.07e-10 Monocyte count; TGCT cis rs3008870 0.677 rs2815354 chr1:67483642 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.97 8.09 0.59 4.6e-13 Lymphocyte percentage of white cells; TGCT cis rs9467773 1.000 rs11756120 chr6:26529808 G/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs2797160 0.651 rs1268066 chr6:126035041 C/T cg05901451 chr6:126070800 HEY2 0.75 6.67 0.51 7.42e-10 Endometrial cancer; TGCT trans rs629535 0.767 rs72654070 chr8:70079369 G/A cg21567404 chr3:27674614 NA -0.57 -8.99 -0.63 3.38e-15 Dupuytren's disease; TGCT cis rs9467711 0.606 rs9379901 chr6:26603866 T/C cg16898833 chr6:26189333 HIST1H4D 1.02 5.25 0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9913156 0.576 rs2036656 chr17:4622071 C/G cg00122941 chr17:4613640 ARRB2 -0.77 -6.91 -0.53 2.22e-10 Lymphocyte counts; TGCT cis rs10504229 0.906 rs58559296 chr8:58171714 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7568458 0.709 rs2592551 chr2:85780131 G/A cg17127132 chr2:85788382 GGCX 0.51 4.58 0.38 1.12e-5 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7267979 1.000 rs6138575 chr20:25438952 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9911578 0.935 rs9911753 chr17:56983174 G/A cg12560992 chr17:57184187 TRIM37 0.73 8.7 0.62 1.69e-14 Intelligence (multi-trait analysis); TGCT cis rs76878669 0.561 rs4244813 chr11:66129488 G/C cg18002602 chr11:66138449 SLC29A2 0.54 6.62 0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs35146811 0.844 rs34031156 chr7:99677917 T/A cg13334819 chr7:99746414 C7orf59 -0.79 -6.8 -0.52 3.94e-10 Coronary artery disease; TGCT cis rs9486719 0.843 rs2499787 chr6:96841762 G/C cg06623918 chr6:96969491 KIAA0776 0.9 6.41 0.5 2.73e-9 Migraine;Coronary artery disease; TGCT cis rs9733 0.650 rs12406712 chr1:150545084 C/A cg13175981 chr1:150552382 MCL1 0.52 5.6 0.45 1.32e-7 Tonsillectomy; TGCT cis rs9916302 0.904 rs7208274 chr17:37513796 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg07092213 chr7:1199455 ZFAND2A 0.43 4.59 0.38 1.05e-5 Longevity;Endometriosis; TGCT cis rs1182196 0.502 rs757786 chr7:2836019 C/T cg11411865 chr7:2701802 TTYH3 0.19 4.52 0.38 1.44e-5 Plateletcrit; TGCT cis rs4886920 0.518 rs12902224 chr15:78076272 T/C cg03457338 chr15:78040120 NA 0.24 5.21 0.42 7.79e-7 Neuroticism; TGCT cis rs2153535 0.580 rs9505455 chr6:8478622 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9467711 0.720 rs9348716 chr6:26375658 G/A cg16898833 chr6:26189333 HIST1H4D 1.1 5.3 0.43 5.16e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs60871478 1.000 rs62432860 chr7:807522 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.6 0.38 1.04e-5 Cerebrospinal P-tau181p levels; TGCT cis rs2797160 0.651 rs1268092 chr6:126029043 A/G cg05901451 chr6:126070800 HEY2 -0.76 -7.14 -0.54 6.93e-11 Endometrial cancer; TGCT cis rs79149102 0.579 rs7163390 chr15:75280426 T/C cg09165964 chr15:75287851 SCAMP5 -1.08 -6.09 -0.48 1.32e-8 Lung cancer; TGCT cis rs1008375 1.000 rs10805359 chr4:17684886 A/G cg10189774 chr4:17578691 LAP3 0.52 4.71 0.39 6.54e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12946454 0.696 rs4792819 chr17:43247957 A/C cg10701640 chr17:43249399 NA 0.52 7.24 0.55 4.11e-11 Systolic blood pressure; TGCT cis rs308403 0.533 rs12644866 chr4:123667604 T/A cg10495464 chr4:123653540 BBS12;LOC729338 0.81 11.72 0.73 8.06e-22 Blood protein levels; TGCT cis rs9457247 1.000 rs402749 chr6:167386104 C/T cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs6671200 1.000 rs6678964 chr1:95694268 C/T cg01206378 chr1:95698827 RWDD3 0.55 4.58 0.38 1.11e-5 Stearic acid (18:0) levels; TGCT cis rs7804356 0.651 rs3801857 chr7:26811484 C/T cg03456212 chr7:26904342 SKAP2 -0.54 -4.6 -0.38 1.04e-5 Type 1 diabetes; TGCT cis rs9527 0.615 rs10883781 chr10:104581130 A/G cg04362960 chr10:104952993 NT5C2 0.59 4.73 0.39 5.97e-6 Arsenic metabolism; TGCT cis rs28595532 0.920 rs56150431 chr4:119764786 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs60871478 1.000 rs62432242 chr7:797715 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.64 0.38 8.77e-6 Cerebrospinal P-tau181p levels; TGCT cis rs6430585 0.583 rs7561565 chr2:136640787 A/C cg07169764 chr2:136633963 MCM6 1.22 11.9 0.73 3.03e-22 Corneal structure; TGCT cis rs1577917 0.958 rs12192546 chr6:86476484 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.68 5.53 0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs3776081 0.568 rs7720799 chr5:149523777 C/T cg18424208 chr5:149546337 CDX1 -0.26 -4.75 -0.39 5.5e-6 Blood protein levels; TGCT cis rs1513670 0.686 rs9303538 chr17:41814083 G/A cg20702314 chr17:41856518 DUSP3;C17orf105 -0.54 -4.46 -0.37 1.78e-5 Bone mineral density (hip); TGCT cis rs4654899 1.000 rs885363 chr1:21325360 C/A cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg09704166 chr2:114031854 PAX8;LOC440839 -0.32 -4.82 -0.4 4.04e-6 Lymphocyte counts; TGCT cis rs10465746 0.780 rs10874424 chr1:84424033 C/T cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT cis rs11719291 0.651 rs1134043 chr3:49200137 G/T cg03060546 chr3:49711283 APEH -0.69 -4.75 -0.39 5.49e-6 Cognitive function; TGCT cis rs9941219 0.528 rs7191218 chr16:50436394 C/T cg08560952 chr16:50278816 NA 0.36 4.55 0.38 1.28e-5 Liver enzyme levels (alanine transaminase); TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg00024416 chr22:24240387 NA -0.25 -4.91 -0.4 2.86e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1480597 0.518 rs7097094 chr10:45210690 A/C cg12063947 chr10:45878068 ALOX5 0.27 4.54 0.38 1.32e-5 Parkinson's disease; TGCT cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg10802521 chr3:52805072 NEK4 -0.67 -8.06 -0.59 5.58e-13 Bipolar disorder; TGCT cis rs2404602 0.692 rs12904198 chr15:77146978 G/A cg26408565 chr15:76604113 ETFA -0.36 -4.53 -0.38 1.36e-5 Blood metabolite levels; TGCT cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7659604 0.540 rs10001092 chr4:122677177 C/T cg19748678 chr4:122722346 EXOSC9 -0.51 -5.0 -0.41 1.89e-6 Type 2 diabetes; TGCT cis rs710216 0.843 rs10890232 chr1:43416514 C/T cg03128534 chr1:43423976 SLC2A1 0.61 5.02 0.41 1.79e-6 Red cell distribution width; TGCT cis rs514406 0.758 rs532242 chr1:53308665 C/G cg22166914 chr1:53195759 ZYG11B 0.41 7.09 0.54 9.16e-11 Monocyte count; TGCT cis rs2579519 0.547 rs11683523 chr2:96544855 T/C cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Diastolic blood pressure; TGCT cis rs782590 0.522 rs12329050 chr2:55894428 G/A cg18811423 chr2:55921094 PNPT1 -0.6 -5.88 -0.47 3.61e-8 Metabolic syndrome; TGCT cis rs1153858 1.000 rs12909158 chr15:45621174 A/G cg26924012 chr15:45694286 SPATA5L1 1.07 14.49 0.79 1.89e-28 Homoarginine levels; TGCT cis rs5769765 0.740 rs2103932 chr22:50272515 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs3741151 1.000 rs7129663 chr11:73045129 C/T cg17517138 chr11:73019481 ARHGEF17 1.22 6.25 0.49 5.95e-9 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs28595532 0.920 rs116607127 chr4:119731072 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs7772486 0.790 rs2814879 chr6:146201743 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.88 0.4 3.15e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3091242 0.933 rs9438904 chr1:25756860 T/C cg23205692 chr1:25664452 TMEM50A 0.5 5.2 0.42 8.14e-7 Erythrocyte sedimentation rate; TGCT cis rs6879260 1.000 rs10903252 chr5:179733934 T/C cg13944838 chr5:179740914 GFPT2 -0.4 -6.42 -0.5 2.66e-9 Height; TGCT cis rs6121246 0.609 rs2149281 chr20:30417918 G/A cg18721089 chr20:30220636 NA -0.36 -4.6 -0.38 1.04e-5 Mean corpuscular hemoglobin; TGCT cis rs56104184 0.690 rs56312501 chr19:49395933 T/C cg15549821 chr19:49342101 PLEKHA4 -0.45 -5.89 -0.47 3.37e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2742234 0.955 rs2075910 chr10:43614230 G/A cg02780029 chr10:43622663 RET -0.25 -4.85 -0.4 3.64e-6 Hirschsprung disease; TGCT cis rs7618915 0.571 rs2289249 chr3:52597664 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs12142240 0.698 rs112068407 chr1:46822291 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7727544 1.000 rs10076701 chr5:131596419 A/G cg24060327 chr5:131705240 SLC22A5 -0.57 -6.03 -0.48 1.75e-8 Blood metabolite levels; TGCT cis rs1035144 0.510 rs12432357 chr14:81299468 A/G cg06600135 chr14:81408086 NA -0.57 -5.35 -0.43 4.18e-7 Male sexual orientation; TGCT cis rs7666738 0.791 rs2081621 chr4:98926753 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12210905 1.000 rs9368499 chr6:27254332 C/T cg08851530 chr6:28072375 NA 1.29 5.49 0.44 2.19e-7 Hip circumference adjusted for BMI; TGCT cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg27588902 chr6:42928151 GNMT -0.56 -6.93 -0.53 2.08e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6545883 0.929 rs10173974 chr2:61748900 C/G cg15711740 chr2:61764176 XPO1 -0.57 -5.29 -0.43 5.25e-7 Tuberculosis; TGCT cis rs6061231 0.631 rs2427310 chr20:60969929 C/G cg24112000 chr20:60950667 NA -0.35 -4.98 -0.41 2.12e-6 Colorectal cancer; TGCT cis rs76788097 0.614 rs7151034 chr14:61820669 T/G cg15891218 chr14:61748354 TMEM30B -0.68 -4.63 -0.38 9.1e-6 Marginal zone lymphoma; TGCT cis rs1552244 1.000 rs2160869 chr3:10079255 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs2229238 0.823 rs61275241 chr1:154504887 T/G cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg11890956 chr21:40555474 PSMG1 1.11 12.39 0.74 1.95e-23 Cognitive function; TGCT cis rs10411936 1.000 rs10411936 chr19:16548375 C/T cg19006008 chr19:16999768 F2RL3 -0.27 -4.73 -0.39 5.88e-6 White blood cell count;Multiple sclerosis; TGCT cis rs12681287 0.752 rs4472493 chr8:87251914 C/T cg27223183 chr8:87520930 FAM82B -0.8 -5.67 -0.45 9.58e-8 Caudate activity during reward; TGCT cis rs1692580 0.840 rs263526 chr1:2173504 T/C cg24578937 chr1:2090814 PRKCZ 0.24 5.32 0.43 4.74e-7 Coronary artery disease; TGCT trans rs6089829 0.962 rs6062778 chr20:61663959 A/G cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs7511006 0.893 rs2038049 chr22:50654888 G/C cg19026356 chr22:50624276 TRABD -0.5 -4.6 -0.38 1.01e-5 Obesity-related traits; TGCT cis rs7098414 0.511 rs7898787 chr10:82156042 G/A cg00277334 chr10:82204260 NA -0.38 -4.98 -0.41 2.08e-6 Post bronchodilator FEV1; TGCT trans rs1814175 0.791 rs9787917 chr11:49937281 C/T cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs9788333 0.762 rs4441120 chr13:21886863 T/A cg10411590 chr13:21900810 NA 0.34 4.75 0.39 5.46e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs1775715 0.678 rs7096139 chr10:32217404 A/C cg14930904 chr10:32216787 ARHGAP12 0.49 4.61 0.38 9.88e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs780096 0.565 rs8179252 chr2:27746832 A/C cg12000995 chr2:27665139 KRTCAP3 -0.39 -4.62 -0.38 9.61e-6 Total body bone mineral density; TGCT cis rs79976124 0.800 rs6918860 chr6:66637741 G/C cg07460842 chr6:66804631 NA 0.58 5.12 0.42 1.14e-6 Type 2 diabetes; TGCT cis rs7731657 0.537 rs2419934 chr5:130295768 T/C cg08523029 chr5:130500466 HINT1 -0.58 -4.84 -0.4 3.8e-6 Fasting plasma glucose; TGCT trans rs7726839 0.540 rs72703083 chr5:595365 C/T cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs7744392 1.000 rs6922548 chr6:35353523 A/G cg06087101 chr6:35551932 FKBP5 0.61 4.56 0.38 1.21e-5 Cataracts in type 2 diabetes; TGCT cis rs317689 0.918 rs689415 chr12:69738139 A/G cg11871910 chr12:69753446 YEATS4 -0.57 -4.88 -0.4 3.13e-6 Response to diuretic therapy; TGCT cis rs2637266 0.967 rs2579748 chr10:78328313 T/C cg18941641 chr10:78392320 NA 0.41 4.98 0.41 2.05e-6 Pulmonary function; TGCT cis rs3812831 0.695 rs7998546 chr13:114939914 C/G cg06611532 chr13:114900021 NA 0.31 5.64 0.45 1.07e-7 Schizophrenia; TGCT cis rs174479 0.647 rs174457 chr11:61656975 T/C cg19610905 chr11:61596333 FADS2 0.59 5.09 0.42 1.27e-6 Sphingolipid levels; TGCT cis rs6860540 0.504 rs4704871 chr5:156919806 A/G cg25387487 chr5:157003181 ADAM19 -0.31 -4.65 -0.39 8.21e-6 Inflammatory skin disease; TGCT cis rs6831352 0.819 rs13832 chr4:99993075 C/A cg12011299 chr4:100065546 ADH4 0.41 5.7 0.46 8.36e-8 Alcohol dependence; TGCT cis rs3784262 0.692 rs4646590 chr15:58303137 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.85e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs72781680 1.000 rs11125372 chr2:24257582 A/T cg08917208 chr2:24149416 ATAD2B -0.81 -4.44 -0.37 1.99e-5 Lymphocyte counts; TGCT cis rs9457247 0.967 rs443570 chr6:167389925 G/A cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs7772486 0.754 rs9386133 chr6:146141213 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.73 0.39 6.04e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs6089829 0.888 rs4809468 chr20:61673566 T/C cg23505145 chr19:12996616 KLF1 0.96 10.09 0.67 7.8e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs2302464 1.000 rs58978163 chr4:15728008 G/A cg18497811 chr4:14860861 NA -0.48 -4.47 -0.37 1.76e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs28595532 0.920 rs112097820 chr4:119746532 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6061231 1.000 rs11908473 chr20:60957770 C/G cg24112000 chr20:60950667 NA -0.36 -5.17 -0.42 9.03e-7 Colorectal cancer; TGCT cis rs6582630 0.519 rs11182021 chr12:38443709 A/T cg26384229 chr12:38710491 ALG10B -0.8 -7.45 -0.56 1.42e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1215050 0.765 rs783925 chr4:98969881 T/C cg05340658 chr4:99064831 C4orf37 -0.43 -5.27 -0.43 5.8e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs7824557 0.627 rs7838897 chr8:11207326 C/A cg21775007 chr8:11205619 TDH 0.73 7.03 0.53 1.23e-10 Retinal vascular caliber; TGCT cis rs4845570 1.000 rs6673002 chr1:151743275 G/T cg07092448 chr1:151763213 TDRKH 1.17 8.92 0.63 5.08e-15 Coronary artery disease; TGCT cis rs1008375 0.966 rs3775923 chr4:17585625 T/C cg18681998 chr4:17616180 MED28 0.85 8.18 0.59 2.86e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs704 0.790 rs4795434 chr17:26716917 G/T cg10342447 chr17:26645325 TMEM97 -0.51 -4.91 -0.4 2.84e-6 Osteoprotegerin levels; TGCT cis rs4253772 0.530 rs79354880 chr22:46746419 C/A cg24881330 chr22:46731750 TRMU 1.06 5.5 0.44 2.08e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs7246657 0.678 rs2972446 chr19:38129893 G/A cg03611452 chr19:38183253 ZNF781 -0.59 -4.76 -0.39 5.34e-6 Coronary artery calcification; TGCT cis rs6951245 0.554 rs76243429 chr7:1152543 C/T cg09177884 chr7:1199841 ZFAND2A -0.7 -5.57 -0.45 1.48e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7582180 0.715 rs764828 chr2:100908634 A/C cg14675211 chr2:100938903 LONRF2 0.46 4.55 0.38 1.28e-5 Intelligence (multi-trait analysis); TGCT cis rs3008870 1.000 rs11208976 chr1:67434411 A/G cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs7208859 0.725 rs9897673 chr17:29243366 T/C cg14008862 chr17:28927542 LRRC37B2 0.67 4.65 0.39 8.47e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs66573146 0.831 rs6832482 chr4:7023433 A/T cg05069807 chr4:6945702 TBC1D14 0.32 5.14 0.42 1.04e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9467711 1.000 rs9467704 chr6:26319486 A/G cg03517284 chr6:25882590 NA 0.87 4.68 0.39 7.52e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1403694 0.695 rs3774292 chr3:186433574 A/T cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs17253792 0.822 rs78922774 chr14:56115302 T/A cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg19626725 chr5:178986131 RUFY1 0.5 6.38 0.5 3.15e-9 Lung cancer; TGCT trans rs66573146 1.000 rs55688389 chr4:7030689 C/G cg07817883 chr1:32538562 TMEM39B 1.81 8.44 0.6 6.87e-14 Granulocyte percentage of myeloid white cells; TGCT cis rs3091242 0.900 rs669063 chr1:25721154 A/G cg10117171 chr1:25599238 RHD -0.37 -6.02 -0.48 1.86e-8 Erythrocyte sedimentation rate; TGCT cis rs7010267 0.543 rs6469803 chr8:120040538 G/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs1568889 0.838 rs7131053 chr11:28143312 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.24 0.71 1.22e-20 Bipolar disorder; TGCT cis rs10089 1.000 rs2898096 chr5:127433214 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.7e-13 Ileal carcinoids; TGCT cis rs763121 0.853 rs6001185 chr22:39052155 G/A cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs597539 0.652 rs611046 chr11:68631704 A/G cg06028808 chr11:68637592 NA 0.53 6.83 0.52 3.33e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs644799 1.000 rs509720 chr11:95562771 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2228479 0.717 rs1061647 chr16:89806063 G/C cg06558623 chr16:89946397 TCF25 0.45 4.51 0.38 1.47e-5 Skin colour saturation; TGCT cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs208520 0.690 rs2144081 chr6:66824972 G/A cg07460842 chr6:66804631 NA -0.95 -9.88 -0.66 2.43e-17 Exhaled nitric oxide output; TGCT cis rs7666738 0.715 rs116787789 chr4:98718720 G/A cg17366294 chr4:99064904 C4orf37 0.65 6.72 0.52 5.97e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7617773 0.780 rs13082859 chr3:48344675 C/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs4819052 0.851 rs2236445 chr21:46678453 T/C cg06618935 chr21:46677482 NA -0.36 -5.39 -0.44 3.4e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3812831 0.654 rs367312 chr13:114930195 G/A cg06611532 chr13:114900021 NA 0.29 5.5 0.44 2.09e-7 Schizophrenia; TGCT cis rs916888 0.773 rs199535 chr17:44822662 A/G cg15921436 chr17:44337874 NA 0.55 7.71 0.57 3.46e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs909674 0.865 rs5757682 chr22:39848259 T/G cg24399712 chr22:39784796 NA -1.05 -11.03 -0.7 3.84e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7635838 0.596 rs443503 chr3:11261912 A/T cg00170343 chr3:11313890 ATG7 -0.62 -5.71 -0.46 7.92e-8 HDL cholesterol; TGCT cis rs6688613 0.694 rs12562794 chr1:166828957 A/G cg07049167 chr1:166818506 POGK 0.25 5.28 0.43 5.7e-7 Refractive astigmatism; TGCT cis rs2730260 0.537 rs73169248 chr7:158891742 T/G cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs9457247 1.000 rs4710147 chr6:167374239 G/A cg25258033 chr6:167368657 RNASET2 -0.18 -4.48 -0.37 1.65e-5 Crohn's disease; TGCT cis rs2012796 0.956 rs10450940 chr14:81825326 C/A cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs10504229 0.683 rs35244711 chr8:58117762 T/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs6754311 0.593 rs11679508 chr2:136474098 A/T cg07169764 chr2:136633963 MCM6 -0.67 -6.08 -0.48 1.41e-8 Mosquito bite size; TGCT cis rs11785400 0.753 rs9773415 chr8:143731170 G/A cg10596483 chr8:143751796 JRK 0.53 5.21 0.42 7.5e-7 Schizophrenia; TGCT cis rs7267979 1.000 rs4815420 chr20:25383979 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6500602 0.627 rs863501 chr16:4588394 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.39 -7.09 -0.54 9.1e-11 Schizophrenia; TGCT cis rs2742417 0.603 rs2673032 chr3:45756927 C/T cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs3824867 0.959 rs4237544 chr11:47454271 G/T cg20307385 chr11:47447363 PSMC3 -0.69 -6.07 -0.48 1.41e-8 Mean corpuscular hemoglobin; TGCT cis rs28595532 0.920 rs55640619 chr4:119761999 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg16145915 chr7:1198662 ZFAND2A -0.54 -7.0 -0.53 1.42e-10 Longevity;Endometriosis; TGCT trans rs941408 1.000 rs1736184 chr19:2810248 G/A cg19676328 chr12:49525230 TUBA1B -0.77 -7.34 -0.55 2.43e-11 Total cholesterol levels; TGCT cis rs59197085 0.515 rs2402938 chr7:128444295 T/C cg00260937 chr7:128520193 KCP 0.46 5.12 0.42 1.15e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs10256972 0.616 rs7806746 chr7:1075573 A/C cg16145915 chr7:1198662 ZFAND2A -0.44 -5.3 -0.43 5.01e-7 Longevity;Endometriosis; TGCT cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg17747265 chr1:1875780 NA -0.39 -7.32 -0.55 2.73e-11 Body mass index; TGCT cis rs28595532 0.920 rs114051506 chr4:119772893 A/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs79075162 chr4:98960674 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 0.933 rs2531726 chr17:56522533 C/T cg12560992 chr17:57184187 TRIM37 -0.7 -8.63 -0.61 2.53e-14 Intelligence (multi-trait analysis); TGCT cis rs6500602 0.702 rs6500605 chr16:4502410 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.28 5.18 0.42 8.68e-7 Schizophrenia; TGCT cis rs5167 0.566 rs7253458 chr19:45482570 C/T cg13119609 chr19:45449297 APOC2 0.23 4.65 0.39 8.26e-6 Blood protein levels; TGCT cis rs651907 0.514 rs10936744 chr3:101433440 C/T cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.02 -0.53 1.27e-10 Colorectal cancer; TGCT cis rs17818399 0.749 rs35625984 chr2:46805908 A/G cg26688816 chr2:46740690 ATP6V1E2 -0.53 -5.24 -0.43 6.72e-7 Height; TGCT cis rs524023 0.914 rs2666559 chr11:64439227 G/T cg19395706 chr11:64412079 NRXN2 -0.43 -5.16 -0.42 9.33e-7 Urate levels in obese individuals; TGCT cis rs7681440 0.647 rs11941682 chr4:90804316 T/G cg10208370 chr4:90758469 SNCA -0.56 -5.27 -0.43 5.93e-7 Dementia with Lewy bodies; TGCT trans rs2727020 0.587 rs1164658 chr11:49298551 C/A cg03929089 chr4:120376271 NA 0.72 8.44 0.6 7.15e-14 Coronary artery disease; TGCT cis rs13256369 0.802 rs13255789 chr8:8562791 T/C cg18904891 chr8:8559673 CLDN23 0.58 5.4 0.44 3.23e-7 Obesity-related traits; TGCT cis rs854765 0.547 rs2955355 chr17:17948475 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.8 -8.46 -0.61 6.18e-14 Total body bone mineral density; TGCT cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs921968 0.541 rs3845835 chr2:219342284 T/C cg02176678 chr2:219576539 TTLL4 -0.48 -6.84 -0.52 3.21e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs3845702 0.736 rs56401468 chr2:180857757 C/T cg01881094 chr2:180872142 CWC22 1.06 6.66 0.51 8.12e-10 Schizophrenia; TGCT cis rs1670533 1.000 rs6858612 chr4:1053353 C/T cg20887711 chr4:1340912 KIAA1530 0.57 4.48 0.37 1.65e-5 Recombination rate (females); TGCT cis rs13256369 0.950 rs12548792 chr8:8568031 T/C cg17143192 chr8:8559678 CLDN23 0.58 5.56 0.45 1.56e-7 Obesity-related traits; TGCT cis rs2153535 0.580 rs1577467 chr6:8444241 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs10953536 chr7:107021691 G/A cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs6754311 0.551 rs313519 chr2:136439517 A/C cg07169764 chr2:136633963 MCM6 0.63 5.62 0.45 1.19e-7 Mosquito bite size; TGCT cis rs28595532 0.920 rs115484560 chr4:119756781 T/G cg14228332 chr4:119757509 SEC24D 1.29 6.0 0.47 1.98e-8 Cannabis dependence symptom count; TGCT cis rs769267 0.930 rs3752151 chr19:19616026 T/C cg03709012 chr19:19516395 GATAD2A 0.74 6.22 0.49 7.04e-9 Tonsillectomy; TGCT cis rs7552404 0.727 rs4949677 chr1:76266662 T/A cg10523679 chr1:76189770 ACADM 0.75 7.12 0.54 7.71e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3796352 0.764 rs11714902 chr3:53101544 G/C cg15956490 chr3:53032818 SFMBT1 0.6 6.81 0.52 3.78e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs250677 0.522 rs1432801 chr5:148390979 T/C cg18129178 chr5:148520854 ABLIM3 -0.35 -4.58 -0.38 1.12e-5 Breast cancer; TGCT cis rs877282 0.945 rs11253397 chr10:789774 A/G cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs4332037 0.539 rs11982455 chr7:1911458 A/C cg25834613 chr7:1915315 MAD1L1 -0.47 -4.63 -0.38 8.98e-6 Bipolar disorder; TGCT cis rs12908161 1.000 rs12908549 chr15:85322351 C/G cg12863693 chr15:85201151 NMB 0.43 5.12 0.42 1.15e-6 Schizophrenia; TGCT cis rs5750830 0.649 rs6001588 chr22:39819049 G/C cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs13242816 1.000 rs62471189 chr7:116101588 G/A cg16553024 chr7:116138462 CAV2 -0.46 -5.15 -0.42 9.77e-7 P wave duration; TGCT trans rs561341 0.714 rs75861674 chr17:30304317 A/G cg20587970 chr11:113659929 NA -1.04 -12.58 -0.75 6.7e-24 Hip circumference adjusted for BMI; TGCT cis rs57994353 0.897 rs72775778 chr9:139381128 G/A cg13741927 chr9:139327495 INPP5E -0.23 -5.12 -0.42 1.12e-6 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9300255 0.568 rs1627724 chr12:123638580 T/A cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs11190604 0.767 rs10883483 chr10:102174244 T/C cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs651907 0.535 rs1460097 chr3:101497569 C/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.52 -0.51 1.56e-9 Colorectal cancer; TGCT cis rs6912958 0.781 rs9450738 chr6:88267314 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs11711311 0.747 rs11928494 chr3:113343219 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.68 -5.83 -0.46 4.6e-8 IgG glycosylation; TGCT cis rs17162190 0.559 rs4402166 chr1:26850406 C/T cg02450742 chr1:26856648 RPS6KA1 0.54 4.49 0.37 1.62e-5 Mean corpuscular volume; TGCT cis rs7772486 0.875 rs9399572 chr6:146362945 T/G cg23711669 chr6:146136114 FBXO30 0.87 9.53 0.65 1.75e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6831352 0.918 rs1042365 chr4:100045500 G/T cg12011299 chr4:100065546 ADH4 -0.42 -5.14 -0.42 1.04e-6 Alcohol dependence; TGCT cis rs2070488 0.932 rs4678604 chr3:38444273 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.66 0.66 8.43e-17 Electrocardiographic conduction measures; TGCT cis rs7819412 0.537 rs2127127 chr8:11434792 C/G cg21775007 chr8:11205619 TDH -0.53 -5.06 -0.41 1.45e-6 Triglycerides; TGCT cis rs10540 1.000 rs61876333 chr11:487136 G/A cg03934478 chr11:495069 RNH1 0.33 5.08 0.42 1.33e-6 Body mass index; TGCT cis rs778371 0.958 rs778341 chr2:233728801 C/A cg08000102 chr2:233561755 GIGYF2 -0.56 -5.99 -0.47 2.12e-8 Schizophrenia; TGCT cis rs1018836 0.665 rs7000724 chr8:91516335 A/T cg16814680 chr8:91681699 NA -0.74 -7.47 -0.56 1.22e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs12477438 0.520 rs13018891 chr2:99755099 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs7819412 0.818 rs11989439 chr8:11055597 C/A cg21775007 chr8:11205619 TDH -0.49 -4.55 -0.38 1.27e-5 Triglycerides; TGCT cis rs6866344 0.570 rs1079487 chr5:178136005 G/A cg10224037 chr5:178157518 ZNF354A 0.99 9.62 0.65 1.03e-16 Neutrophil percentage of white cells; TGCT trans rs1814175 0.754 rs7103235 chr11:49699191 A/G cg15704280 chr7:45808275 SEPT13 -0.7 -8.14 -0.59 3.51e-13 Height; TGCT cis rs10504229 0.683 rs7822631 chr8:58130916 C/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9399137 0.507 rs4520025 chr6:135278619 G/T cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs12135062 0.538 rs2651929 chr1:3101353 C/T cg25382214 chr1:3105252 PRDM16 0.22 4.44 0.37 2.01e-5 Migraine; TGCT cis rs3617 0.573 rs3821873 chr3:52913006 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.51 4.97 0.41 2.18e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7191439 0.858 rs4390574 chr16:88776297 T/C cg27087555 chr16:88793112 FAM38A -0.5 -5.49 -0.44 2.16e-7 Plateletcrit; TGCT cis rs4689592 0.503 rs11945642 chr4:7051065 G/C cg02503808 chr4:7069936 GRPEL1 -0.94 -7.53 -0.56 9.02e-12 Monocyte percentage of white cells; TGCT cis rs919433 0.617 rs10460394 chr2:198548741 G/A cg00792783 chr2:198669748 PLCL1 -0.56 -5.11 -0.42 1.21e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs929596 0.755 rs4148325 chr2:234673309 C/T cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.33 -5.5 -0.44 2.12e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs4689592 0.546 rs10937782 chr4:7057106 G/C cg02503808 chr4:7069936 GRPEL1 0.97 9.11 0.63 1.78e-15 Monocyte percentage of white cells; TGCT cis rs7511006 0.893 rs760743 chr22:50647375 C/T cg08875078 chr22:50639485 SELO 0.57 5.45 0.44 2.59e-7 Obesity-related traits; TGCT cis rs9611565 0.512 rs139560 chr22:42194962 A/G cg06634786 chr22:41940651 POLR3H -0.82 -7.77 -0.57 2.62e-12 Vitiligo; TGCT cis rs9911578 0.967 rs6503893 chr17:57149695 G/A cg05425664 chr17:57184151 TRIM37 -0.68 -6.9 -0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs13326165 0.760 rs13059674 chr3:52371789 T/G cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs13242816 0.881 rs35062002 chr7:116142458 G/A cg16553024 chr7:116138462 CAV2 -0.44 -5.36 -0.43 3.97e-7 P wave duration; TGCT cis rs6688613 1.000 rs6688613 chr1:166951869 A/G cg07049167 chr1:166818506 POGK -0.21 -4.52 -0.38 1.43e-5 Refractive astigmatism; TGCT cis rs8177253 0.896 rs34252038 chr3:133490621 G/T cg08048268 chr3:133502702 NA -0.64 -9.81 -0.66 3.59e-17 Iron status biomarkers; TGCT cis rs28386778 0.863 rs8076760 chr17:61920497 T/C cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs2549003 1.000 rs7735073 chr5:131815357 G/A cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs6938 0.618 rs11638130 chr15:75183935 G/A cg09165964 chr15:75287851 SCAMP5 0.58 5.33 0.43 4.45e-7 Breast cancer; TGCT cis rs909341 0.537 rs12481497 chr20:62385541 G/A cg14758556 chr20:62440591 NA 0.4 5.74 0.46 6.9e-8 Atopic dermatitis; TGCT cis rs2016266 0.859 rs7953656 chr12:53738433 G/T cg16917193 chr12:54089295 NA 0.66 4.54 0.38 1.33e-5 Bone mineral density (spine);Bone mineral density; TGCT cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.68 4.89 0.4 3e-6 Platelet count; TGCT trans rs1005277 0.540 rs7903942 chr10:37929276 C/T cg17830980 chr10:43048298 ZNF37B 0.67 7.5 0.56 1.07e-11 Extrinsic epigenetic age acceleration; TGCT cis rs2204008 0.837 rs11495722 chr12:38337245 G/A cg13010199 chr12:38710504 ALG10B 0.61 4.77 0.39 5.11e-6 Bladder cancer; TGCT cis rs12468579 0.503 rs1168 chr2:191829777 C/T cg21497043 chr2:191745649 GLS 0.51 4.66 0.39 8.05e-6 JT interval (sulfonylurea treatment interaction); TGCT cis rs1552244 0.935 rs4441636 chr3:10083876 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs11578119 0.689 rs6689586 chr1:170392301 C/T cg09767346 chr1:170501363 GORAB -0.57 -4.7 -0.39 6.94e-6 Male-pattern baldness; TGCT cis rs826838 0.967 rs7136593 chr12:39128265 C/T cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs6088590 1.000 rs11696546 chr20:33452999 C/G cg24642439 chr20:33292090 TP53INP2 0.7 5.98 0.47 2.17e-8 Coronary artery disease; TGCT cis rs62103177 0.759 rs9956512 chr18:77607517 G/A cg12964065 chr18:77638022 KCNG2 0.41 5.48 0.44 2.31e-7 Opioid sensitivity; TGCT cis rs13242816 1.000 rs56180538 chr7:116079711 C/T cg16553024 chr7:116138462 CAV2 -0.47 -5.23 -0.43 6.88e-7 P wave duration; TGCT cis rs6456156 0.792 rs10946213 chr6:167516095 A/G cg07741184 chr6:167504864 NA -0.23 -4.7 -0.39 6.8e-6 Primary biliary cholangitis; TGCT cis rs765787 0.530 rs1631533 chr15:45518628 C/T cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs4975709 0.569 rs2353583 chr5:1858834 G/C cg14773178 chr5:1868261 NA 0.34 5.62 0.45 1.18e-7 Cardiovascular disease risk factors; TGCT cis rs2239547 0.618 rs3733047 chr3:52871929 A/G cg10802521 chr3:52805072 NEK4 0.6 6.07 0.48 1.44e-8 Schizophrenia; TGCT cis rs860295 0.557 rs6696019 chr1:155864977 T/C cg05700447 chr1:155978627 NA 0.23 4.72 0.39 6.14e-6 Body mass index; TGCT cis rs9611565 0.921 rs5751080 chr22:41736267 A/G cg13695892 chr22:41940480 POLR3H -0.72 -7.37 -0.55 2.15e-11 Vitiligo; TGCT cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs3812831 0.572 rs3118896 chr13:114931769 C/G cg08824895 chr13:115047677 UPF3A 0.5 5.02 0.41 1.75e-6 Schizophrenia; TGCT cis rs8031584 0.706 rs2177670 chr15:31157751 G/T cg08704250 chr15:31115839 NA -0.43 -6.31 -0.49 4.47e-9 Huntington's disease progression; TGCT cis rs7711186 0.655 rs75315590 chr5:178020818 A/T cg17371294 chr5:178012716 COL23A1 -0.57 -4.71 -0.39 6.39e-6 Urate levels in obese individuals; TGCT trans rs17685 0.712 rs10271413 chr7:75754858 G/A cg19862616 chr7:65841803 NCRNA00174 0.52 8.96 0.63 4.04e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs10782582 0.593 rs12130832 chr1:76234294 T/C cg22875332 chr1:76189707 ACADM -0.45 -4.98 -0.41 2.06e-6 Daytime sleep phenotypes; TGCT cis rs7829975 0.633 rs2979181 chr8:8323088 A/T cg15556689 chr8:8085844 FLJ10661 0.71 6.71 0.52 6.06e-10 Mood instability; TGCT cis rs2404602 0.536 rs12915248 chr15:76765615 A/T cg22467129 chr15:76604101 ETFA -0.49 -5.95 -0.47 2.53e-8 Blood metabolite levels; TGCT cis rs6586163 0.527 rs3740286 chr10:90751340 A/G cg03111039 chr10:90751583 FAS;ACTA2 0.6 7.77 0.57 2.59e-12 Chronic lymphocytic leukemia; TGCT cis rs1784581 0.722 rs1619122 chr6:162400198 G/T cg17173639 chr6:162384350 PARK2 -0.47 -8.25 -0.6 1.94e-13 Itch intensity from mosquito bite; TGCT cis rs9583531 0.689 rs9521913 chr13:111382058 C/T cg24331049 chr13:111365604 ING1 -0.88 -8.83 -0.62 8.12e-15 Coronary artery disease; TGCT cis rs4455778 0.659 rs2364008 chr7:49017001 A/G cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs7727544 0.570 rs7701237 chr5:131534381 C/T cg14196790 chr5:131705035 SLC22A5 0.33 4.49 0.37 1.59e-5 Blood metabolite levels; TGCT cis rs56104184 0.775 rs73061694 chr19:49399978 T/C cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs875971 0.895 rs10447522 chr7:65796074 A/G cg11764359 chr7:65958608 NA -0.55 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs2180341 0.960 rs9375503 chr6:127677071 T/C cg27446573 chr6:127587934 RNF146 1.21 10.87 0.7 9.57e-20 Breast cancer; TGCT cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg03806693 chr22:41940476 POLR3H 1.06 10.94 0.7 6.7e-20 Crohn's disease;Inflammatory bowel disease; TGCT cis rs5769765 1.000 rs4824112 chr22:50284345 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.42 6.28 0.49 5.18e-9 Schizophrenia; TGCT cis rs2594989 0.943 rs2594995 chr3:11369117 A/G cg00170343 chr3:11313890 ATG7 -0.67 -5.06 -0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs478304 0.934 rs1193692 chr11:65504069 A/C cg17480646 chr11:65405466 SIPA1 0.43 5.24 0.43 6.71e-7 Acne (severe); TGCT cis rs9611565 0.694 rs9611591 chr22:41830212 G/A cg17554472 chr22:41940697 POLR3H 0.47 5.17 0.42 8.97e-7 Vitiligo; TGCT cis rs7824557 0.591 rs2293859 chr8:11216761 T/G cg21775007 chr8:11205619 TDH 0.69 6.65 0.51 8.29e-10 Retinal vascular caliber; TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg11965913 chr1:205819406 PM20D1 -0.46 -6.44 -0.5 2.34e-9 Monocyte percentage of white cells; TGCT cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg17971929 chr21:40555470 PSMG1 -0.51 -4.47 -0.37 1.74e-5 Menarche (age at onset); TGCT cis rs4665809 0.590 rs7582341 chr2:26416301 A/G cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.58e-9 Gut microbiome composition (summer); TGCT cis rs2439831 0.850 rs28718261 chr15:44043793 C/G cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs669446 0.527 rs585711 chr1:44099863 G/T cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs7824557 0.602 rs10110557 chr8:11207508 T/C cg21775007 chr8:11205619 TDH 0.73 7.03 0.53 1.23e-10 Retinal vascular caliber; TGCT cis rs7246657 0.525 rs997516 chr19:37474264 T/C cg18154014 chr19:37997991 ZNF793 0.73 4.58 0.38 1.11e-5 Coronary artery calcification; TGCT cis rs59197085 0.818 rs4472439 chr7:128466635 G/A cg00260937 chr7:128520193 KCP 0.47 4.95 0.41 2.36e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs7677751 0.767 rs6831380 chr4:55076345 G/A cg17187183 chr4:55093834 PDGFRA 0.48 6.4 0.5 2.84e-9 Corneal astigmatism; TGCT cis rs4631830 0.863 rs10826127 chr10:51530757 G/A cg10326726 chr10:51549505 MSMB -0.27 -5.38 -0.43 3.6e-7 Prostate-specific antigen levels; TGCT cis rs2243480 1.000 rs778691 chr7:65873092 G/C cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs4730250 0.554 rs76257331 chr7:106916279 G/A cg02696742 chr7:106810147 HBP1 -0.68 -5.2 -0.42 8.03e-7 Osteoarthritis; TGCT cis rs9303401 0.659 rs35539277 chr17:56853833 G/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs13108904 0.905 rs1732108 chr4:1276550 C/T cg13342137 chr4:2252803 MXD4 -0.17 -4.44 -0.37 2e-5 Obesity-related traits; TGCT cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg06634786 chr22:41940651 POLR3H 0.87 8.2 0.59 2.56e-13 Vitiligo; TGCT cis rs1783925 0.881 rs643446 chr11:125306472 T/C cg03464685 chr11:125439445 EI24 -0.6 -5.04 -0.41 1.63e-6 Formal thought disorder in schizophrenia; TGCT cis rs208520 0.560 rs2351880 chr6:66863707 G/A cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs12210905 1.000 rs9348758 chr6:27255238 T/G cg08851530 chr6:28072375 NA 1.29 5.49 0.44 2.19e-7 Hip circumference adjusted for BMI; TGCT cis rs7208859 0.623 rs34756112 chr17:29113016 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4253772 0.678 rs9627281 chr22:46644168 A/G cg09491104 chr22:46646882 C22orf40 -0.5 -5.35 -0.43 4.04e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs6815814 0.847 rs11725309 chr4:38783848 T/C cg02016764 chr4:38805732 TLR1 -0.36 -5.54 -0.45 1.71e-7 Breast cancer; TGCT cis rs149866169 1 rs149866169 chr6:27441723 T/A cg26587870 chr6:27730563 NA -0.47 -4.49 -0.37 1.6e-5 Neuroticism (multi-trait analysis);Lung cancer in ever smokers;Subjective well-being (multi-trait analysis);Lung cancer;Squamous cell lung carcinoma; TGCT cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg03517284 chr6:25882590 NA 0.64 5.8 0.46 5.28e-8 Intelligence (multi-trait analysis); TGCT cis rs1799949 1.000 rs4793229 chr17:41418334 C/T cg19454999 chr17:41278357 BRCA1;NBR2 -0.51 -5.37 -0.43 3.71e-7 Menopause (age at onset); TGCT cis rs6088580 0.634 rs6087580 chr20:32992592 A/G cg06115741 chr20:33292138 TP53INP2 -0.52 -4.52 -0.38 1.44e-5 Glomerular filtration rate (creatinine); TGCT cis rs9302065 0.595 rs1547746 chr13:95964267 G/A cg24476569 chr13:95954382 ABCC4 -0.48 -6.93 -0.53 2.08e-10 Blood metabolite levels; TGCT cis rs2836633 0.965 rs2836621 chr21:40054149 C/T cg05519781 chr21:40033154 ERG 0.55 5.48 0.44 2.24e-7 Coronary artery disease; TGCT cis rs76878669 0.538 rs1546358 chr11:66175261 G/C cg18002602 chr11:66138449 SLC29A2 0.53 6.41 0.5 2.75e-9 Educational attainment (years of education); TGCT cis rs6484504 0.576 rs11031324 chr11:31250299 T/C cg14844989 chr11:31128820 NA -0.25 -4.88 -0.4 3.24e-6 Red blood cell count; TGCT cis rs35000415 0.938 rs71581958 chr7:128665542 C/T cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs950169 0.580 rs1061737 chr15:85183790 G/C cg11189052 chr15:85197271 WDR73 0.73 6.01 0.47 1.96e-8 Schizophrenia; TGCT cis rs2255336 0.608 rs7957681 chr12:10518822 G/A cg16084090 chr12:10586130 KLRC2 0.3 4.62 0.38 9.55e-6 Blood protein levels; TGCT cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.69 4.91 0.4 2.75e-6 Platelet count; TGCT cis rs2180341 0.722 rs9388555 chr6:127576363 G/A cg27446573 chr6:127587934 RNF146 0.98 8.94 0.63 4.63e-15 Breast cancer; TGCT cis rs2439831 0.764 rs12324584 chr15:43683446 G/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.14 0.59 3.58e-13 Lung cancer in ever smokers; TGCT trans rs524675 0.581 rs527273 chr4:13957156 G/A cg02315626 chr17:27188560 MIR451;MIR144 0.42 6.87 0.53 2.82e-10 Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs909674 0.734 rs5757675 chr22:39838892 G/T cg02038168 chr22:39784481 NA -0.71 -5.56 -0.45 1.55e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs877282 0.898 rs11253338 chr10:759559 C/T cg17470449 chr10:769945 NA 0.33 4.85 0.4 3.58e-6 Uric acid levels; TGCT cis rs9467773 0.869 rs9295689 chr6:26455811 T/C cg15659132 chr6:26577336 NA 0.61 6.86 0.52 2.96e-10 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.541 rs9379207 chr6:8458186 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9818758 0.505 rs11716159 chr3:49631585 G/A cg07636037 chr3:49044803 WDR6 -0.98 -4.72 -0.39 6.18e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6683383 1.000 rs722915 chr1:203087657 C/T cg04395153 chr1:203052423 MYOG -0.27 -4.48 -0.37 1.66e-5 Asthma; TGCT cis rs12220238 1.000 rs10824102 chr10:75948915 C/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs3099143 1.000 rs35645941 chr15:77140302 C/T cg21673338 chr15:77095150 SCAPER -0.52 -5.05 -0.41 1.54e-6 Recalcitrant atopic dermatitis; TGCT cis rs6582630 0.576 rs2222345 chr12:38356020 G/A cg26384229 chr12:38710491 ALG10B -0.53 -4.66 -0.39 8.04e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg08048268 chr3:133502702 NA -0.53 -7.17 -0.54 5.89e-11 Iron status biomarkers; TGCT cis rs854765 0.583 rs4413022 chr17:17858280 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs514406 0.505 rs269286 chr1:53169018 C/T cg24675658 chr1:53192096 ZYG11B 0.77 8.88 0.62 6.42e-15 Monocyte count; TGCT cis rs2072499 0.833 rs2251636 chr1:156202809 G/C cg25208724 chr1:156163844 SLC25A44 0.96 12.22 0.74 4.94e-23 Testicular germ cell tumor; TGCT cis rs6087990 0.735 rs2424906 chr20:31359109 A/G cg13636640 chr20:31349939 DNMT3B 0.95 12.44 0.75 1.49e-23 Ulcerative colitis; TGCT cis rs288326 0.561 rs41270217 chr2:183850877 C/T cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs782590 0.807 rs782572 chr2:55912120 T/C cg03859395 chr2:55845619 SMEK2 0.82 9.59 0.65 1.27e-16 Metabolic syndrome; TGCT cis rs9948 0.786 rs56797569 chr2:97413555 G/T cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs7552404 0.731 rs10873787 chr1:76367797 G/A cg22875332 chr1:76189707 ACADM 0.7 6.84 0.52 3.26e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2243480 1.000 rs781149 chr7:65481284 C/T cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs11711311 1.000 rs12637067 chr3:113527606 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs4389656 0.695 rs1532333 chr5:6770502 C/T cg12187999 chr5:6845652 NA -0.34 -4.78 -0.39 4.94e-6 Coronary artery disease; TGCT cis rs7659604 0.702 rs6826506 chr4:122710865 T/G cg19748678 chr4:122722346 EXOSC9 0.9 9.48 0.65 2.3e-16 Type 2 diabetes; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg08736216 chr1:53307985 ZYG11A -0.24 -4.74 -0.39 5.75e-6 Monocyte count; TGCT cis rs1153858 1.000 rs12101539 chr15:45650666 C/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs877282 0.842 rs7092986 chr10:756373 G/A cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs3091242 0.933 rs9645452 chr1:25668326 C/T cg09222892 chr1:25734099 RHCE 0.44 7.1 0.54 8.59e-11 Erythrocyte sedimentation rate; TGCT cis rs3782455 1.000 rs78363483 chr12:114401643 T/C cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6570726 0.967 rs450973 chr6:145863065 C/A cg05347473 chr6:146136440 FBXO30 0.5 4.44 0.37 1.99e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs651907 0.535 rs34063583 chr3:101509948 C/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg13683864 chr3:40499215 RPL14 -1.11 -11.84 -0.73 4.15e-22 Renal cell carcinoma; TGCT cis rs7819412 0.875 rs6981523 chr8:11061792 C/T cg27411982 chr8:10470053 RP1L1 -0.2 -4.46 -0.37 1.84e-5 Triglycerides; TGCT cis rs7611238 0.560 rs1994881 chr3:195140441 T/C cg27323046 chr3:195102265 ACAP2 0.37 4.97 0.41 2.19e-6 Body mass index; TGCT cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.23e-9 Blood metabolite levels; TGCT cis rs7119 0.635 rs907374 chr15:77884026 C/T cg27398640 chr15:77910606 LINGO1 0.33 6.9 0.53 2.37e-10 Type 2 diabetes; TGCT cis rs2439831 1.000 rs527921 chr15:43770416 G/T cg27015174 chr15:43622946 ADAL;LCMT2 -0.82 -5.29 -0.43 5.3e-7 Lung cancer in ever smokers; TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg21226059 chr5:178986404 RUFY1 0.51 5.4 0.44 3.2e-7 Lung cancer; TGCT cis rs7617773 0.817 rs3731534 chr3:48211777 C/T cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT trans rs10203711 1.000 rs907108 chr2:239566285 T/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.64 -0.51 8.76e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs8028182 0.636 rs8030802 chr15:75813153 A/G cg20655648 chr15:75932815 IMP3 0.59 4.62 0.38 9.55e-6 Sudden cardiac arrest; TGCT cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg22029157 chr1:209979665 IRF6 0.76 6.24 0.49 6.3e-9 Cleft lip with or without cleft palate; TGCT cis rs9348729 1 rs9348729 chr6:26664268 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.61 -4.95 -0.41 2.33e-6 Intelligence (multi-trait analysis); TGCT trans rs877282 0.945 rs12767287 chr10:787310 A/G cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs2046867 0.908 rs62251639 chr3:72801214 G/A cg25664220 chr3:72788482 NA -0.56 -7.03 -0.53 1.25e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9467711 1.000 rs9467707 chr6:26327905 G/C cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7017914 0.967 rs10089583 chr8:71849484 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.52 -4.81 -0.4 4.3e-6 Bone mineral density; TGCT cis rs10504229 0.545 rs56394419 chr8:58128982 T/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs986417 1.000 rs2350900 chr14:60938681 T/A cg27398547 chr14:60952738 C14orf39 1.31 8.57 0.61 3.4e-14 Gut microbiota (bacterial taxa); TGCT cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs704 0.628 rs1128162 chr17:26721791 C/A cg10342447 chr17:26645325 TMEM97 -0.47 -4.69 -0.39 7.21e-6 Osteoprotegerin levels; TGCT cis rs3733585 0.624 rs7376154 chr4:9952587 C/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.63 -0.51 9.3e-10 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs3780486 0.757 rs10758189 chr9:33125804 A/G cg20290983 chr6:43655470 MRPS18A 1.15 14.06 0.78 1.98e-27 IgG glycosylation; TGCT cis rs73058052 0.530 rs10421333 chr19:50086080 A/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.65 5.22 0.42 7.36e-7 Fibrinogen levels; TGCT cis rs514406 0.505 rs427319 chr1:53178807 T/G cg16325326 chr1:53192061 ZYG11B 0.85 12.13 0.74 8.13e-23 Monocyte count; TGCT cis rs6540559 0.673 rs41305104 chr1:209950848 G/A cg23283495 chr1:209979779 IRF6 0.63 4.7 0.39 6.71e-6 Cleft lip with or without cleft palate; TGCT trans rs1814175 0.817 rs6486046 chr11:49997017 T/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg07317062 chr7:27170388 HOXA4 -0.44 -4.62 -0.38 9.57e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7833790 0.724 rs10958045 chr8:82722994 T/C cg06027949 chr8:82754900 SNX16 -0.65 -5.03 -0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs61776719 0.520 rs12569027 chr1:38449163 C/T cg26398791 chr1:38455867 SF3A3 -0.47 -4.56 -0.38 1.19e-5 Coronary artery disease; TGCT cis rs7582180 0.614 rs10193204 chr2:101004540 A/G cg08017756 chr2:100939284 LONRF2 0.28 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs9790314 0.586 rs11710086 chr3:161125858 A/T cg03342759 chr3:160939853 NMD3 -0.55 -5.7 -0.46 8.15e-8 Morning vs. evening chronotype; TGCT cis rs4566357 0.615 rs10178098 chr2:227914425 C/T cg11843606 chr2:227700838 RHBDD1 -0.54 -5.25 -0.43 6.53e-7 Coronary artery disease; TGCT cis rs7772486 0.720 rs1890171 chr6:146072114 T/C cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs1075232 0.522 rs57924788 chr15:31749722 G/A cg01030201 chr15:31746330 NA -0.65 -4.46 -0.37 1.85e-5 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg25703541 chr22:24373054 LOC391322 -0.81 -8.7 -0.62 1.68e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7172809 0.599 rs17471753 chr15:77763809 C/T cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs7811142 1.000 rs67471932 chr7:100009985 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs6484504 0.576 rs11031323 chr11:31245413 T/G cg26647111 chr11:31128758 NA -0.34 -4.73 -0.39 5.88e-6 Red blood cell count; TGCT cis rs17826219 0.706 rs9893922 chr17:29068425 T/C cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Body mass index; TGCT cis rs6912958 1.000 rs2207144 chr6:88150816 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.37 -4.74 -0.39 5.79e-6 Monocyte percentage of white cells; TGCT cis rs6964587 0.610 rs6942852 chr7:91437883 A/C cg17063962 chr7:91808500 NA 0.73 6.71 0.52 6.06e-10 Breast cancer; TGCT cis rs295140 1.000 rs7584810 chr2:201167772 G/A cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs7412746 0.658 rs12097963 chr1:150870450 T/C cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT trans rs3780486 0.846 rs10813950 chr9:33127640 A/G cg04842962 chr6:43655489 MRPS18A -1.11 -9.81 -0.66 3.67e-17 IgG glycosylation; TGCT cis rs453301 0.686 rs1045527 chr8:8890041 A/G cg11995313 chr8:8860691 ERI1 0.5 4.5 0.37 1.56e-5 Joint mobility (Beighton score); TGCT cis rs2594989 0.887 rs2454498 chr3:11500953 A/G cg00170343 chr3:11313890 ATG7 0.69 5.12 0.42 1.16e-6 Circulating chemerin levels; TGCT cis rs11997175 0.574 rs4538830 chr8:33653741 C/G ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg03303774 chr4:1407052 NA 0.27 4.56 0.38 1.2e-5 Obesity-related traits; TGCT cis rs4851254 0.660 rs1821830 chr2:100680279 C/T cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs7635838 0.653 rs2606749 chr3:11373635 A/G cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.29e-8 HDL cholesterol; TGCT cis rs1008375 0.932 rs12500947 chr4:17603424 C/T cg10189774 chr4:17578691 LAP3 0.67 5.69 0.45 8.77e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10791097 0.720 rs6590515 chr11:130733365 A/G cg12179176 chr11:130786555 SNX19 -0.84 -10.73 -0.69 2.18e-19 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3741151 0.892 rs7125949 chr11:73009084 G/A cg17517138 chr11:73019481 ARHGEF17 0.93 5.04 0.41 1.59e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs11741688 0.597 rs6880072 chr5:178334480 G/C cg09339527 chr5:178322752 ZFP2 -0.29 -4.85 -0.4 3.57e-6 Sleep duration; TGCT cis rs13108904 0.934 rs4974596 chr4:1301052 A/G cg00684032 chr4:1343700 KIAA1530 0.24 5.14 0.42 1.05e-6 Obesity-related traits; TGCT cis rs875971 1.000 rs709597 chr7:65825983 A/G cg11764359 chr7:65958608 NA -0.6 -5.47 -0.44 2.43e-7 Aortic root size; TGCT cis rs6998277 0.830 rs6468838 chr8:103609336 T/C cg10187029 chr8:103597600 NA 0.56 8.82 0.62 8.69e-15 Migraine; TGCT cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs6969780 0.915 rs886339 chr7:27190670 A/C cg04321618 chr7:27170880 HOXA4 -0.52 -4.5 -0.38 1.51e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs601339 1.000 rs525215 chr12:123179771 G/A cg11919336 chr12:123188078 GPR109A 0.64 7.86 0.58 1.61e-12 Adiponectin levels; TGCT cis rs1552244 0.572 rs113406084 chr3:10170190 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs6933660 0.720 rs6914656 chr6:151753421 C/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.88 -9.67 -0.66 8.12e-17 Menarche (age at onset); TGCT cis rs13191362 0.507 rs2846536 chr6:163033492 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.59 5.98 0.47 2.21e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6456156 0.526 rs3093025 chr6:167532731 A/G cg07741184 chr6:167504864 NA -0.23 -4.66 -0.39 7.98e-6 Primary biliary cholangitis; TGCT cis rs2228479 0.717 rs17233678 chr16:89809962 T/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs6141769 0.542 rs7360824 chr20:31315158 A/G cg13636640 chr20:31349939 DNMT3B -0.51 -4.48 -0.37 1.68e-5 Subjective well-being; TGCT cis rs9660180 0.967 rs10907191 chr1:1774820 A/T cg20999797 chr1:1681921 NA 0.18 4.66 0.39 7.9e-6 Body mass index; TGCT cis rs73198271 0.710 rs11779565 chr8:8680020 G/A cg06671706 chr8:8559999 CLDN23 -0.35 -4.46 -0.37 1.84e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs57590327 0.503 rs2372905 chr3:81504592 C/G cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs7666738 0.962 rs13147921 chr4:99069296 C/G cg17366294 chr4:99064904 C4orf37 0.76 6.63 0.51 9.04e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2440129 0.632 rs2292353 chr17:6903537 C/T cg03407747 chr17:6899364 ALOX12 0.53 5.72 0.46 7.68e-8 Tonsillectomy; TGCT cis rs854765 0.663 rs3744115 chr17:17749822 G/A cg09796270 chr17:17721594 SREBF1 -0.3 -5.86 -0.47 3.85e-8 Total body bone mineral density; TGCT cis rs1023500 0.573 rs8135801 chr22:42475568 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Schizophrenia; TGCT cis rs60843830 0.964 rs7584915 chr2:264227 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.75 7.57 0.56 7.28e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs3806843 0.548 rs246057 chr5:140325583 A/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT trans rs11088226 0.681 rs1015047 chr21:33949423 A/G cg09050820 chr6:167586206 TCP10L2 0.74 7.3 0.55 2.96e-11 Gastritis; TGCT cis rs7635838 0.819 rs2454478 chr3:11541885 A/G cg00170343 chr3:11313890 ATG7 0.67 6.26 0.49 5.88e-9 HDL cholesterol; TGCT cis rs9653442 0.564 rs2164711 chr2:100775422 G/T cg07810366 chr2:100720526 AFF3 -0.34 -5.13 -0.42 1.1e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs12599106 0.792 rs12597352 chr16:34638507 A/T cg01516881 chr6:292596 DUSP22 -0.71 -7.45 -0.56 1.35e-11 Menopause (age at onset); TGCT cis rs6831352 0.918 rs29001224 chr4:100047373 G/A cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs6582630 0.555 rs11182202 chr12:38476451 C/G cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs736408 0.608 rs4687657 chr3:52852538 G/T cg11645453 chr3:52864694 ITIH4 0.31 5.34 0.43 4.24e-7 Bipolar disorder; TGCT cis rs2786098 0.577 rs10922305 chr1:197821769 C/T cg00114966 chr1:197893920 LHX9 -0.38 -4.62 -0.38 9.54e-6 Asthma; TGCT cis rs9291683 0.669 rs887733 chr4:10183108 T/C cg11266682 chr4:10021025 SLC2A9 -0.45 -4.95 -0.41 2.36e-6 Bone mineral density; TGCT cis rs1008375 1.000 rs1008375 chr4:17682834 T/C cg16339924 chr4:17578868 LAP3 0.53 4.69 0.39 7.15e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs1005277 0.505 rs200910 chr10:38108176 C/T cg17830980 chr10:43048298 ZNF37B -0.72 -8.22 -0.59 2.27e-13 Extrinsic epigenetic age acceleration; TGCT cis rs9443189 0.570 rs7770824 chr6:76408189 G/A cg01950844 chr6:76311363 SENP6 1.0 6.24 0.49 6.35e-9 Prostate cancer; TGCT cis rs11748023 0.605 rs155949 chr5:139523684 A/G cg01081189 chr5:139537190 NA 0.26 4.62 0.38 9.47e-6 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs654071 chr11:68653432 A/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.13 0.59 3.82e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs875971 0.964 rs6978721 chr7:65883204 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs7666738 0.830 rs7687958 chr4:99014495 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.679 rs4819053 chr21:46711357 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 -0.61 -5.89 -0.47 3.45e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1568889 1.000 rs7937117 chr11:28370038 C/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.8 7.92 0.58 1.13e-12 Bipolar disorder; TGCT cis rs1218582 0.774 rs12036859 chr1:154859940 A/C cg06221963 chr1:154839813 KCNN3 0.8 15.27 0.81 2.9e-30 Prostate cancer; TGCT cis rs9942416 0.660 rs2047059 chr5:75008193 T/C cg02573091 chr5:74908125 NA 0.44 4.95 0.41 2.4e-6 Age-related disease endophenotypes; TGCT cis rs12497850 0.897 rs6795025 chr3:49081247 T/C cg07636037 chr3:49044803 WDR6 0.97 10.64 0.69 3.45e-19 Parkinson's disease; TGCT cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg03264133 chr6:25882463 NA -0.66 -6.03 -0.48 1.76e-8 Intelligence (multi-trait analysis); TGCT cis rs9581857 0.547 rs17753121 chr13:28052613 T/C cg22138327 chr13:27999177 GTF3A 0.74 4.82 0.4 4.15e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs35160687 0.798 rs11127029 chr2:86554625 C/G cg03171300 chr2:86307199 POLR1A -0.27 -4.59 -0.38 1.07e-5 Night sleep phenotypes; TGCT cis rs1129187 0.755 rs2274517 chr6:42932715 A/G cg10862848 chr6:42927986 GNMT 0.38 4.72 0.39 6.35e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs8016982 0.662 rs9806020 chr14:81668555 A/C cg01989461 chr14:81687754 GTF2A1 0.62 4.65 0.39 8.47e-6 Schizophrenia; TGCT cis rs6951245 0.529 rs76001997 chr7:1152615 C/T cg18402987 chr7:1209562 NA 0.47 4.69 0.39 7.03e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9972944 0.899 rs9972954 chr17:63771050 T/C cg07283582 chr17:63770753 CCDC46 0.28 5.89 0.47 3.36e-8 Total body bone mineral density; TGCT cis rs7666738 0.830 rs11097605 chr4:98985167 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs644799 0.965 rs11021317 chr11:95517576 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.91 11.08 0.71 2.9e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6912958 0.535 rs1753154 chr6:88032843 G/C cg12350822 chr6:88032061 C6orf162;GJB7 0.43 5.57 0.45 1.51e-7 Monocyte percentage of white cells; TGCT cis rs780096 0.526 rs3845687 chr2:27689899 T/C cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT cis rs9926296 0.744 rs154656 chr16:89708003 T/A cg01097406 chr16:89675127 NA 0.35 6.22 0.49 6.81e-9 Vitiligo; TGCT cis rs9733 0.569 rs11588404 chr1:150688529 C/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs9858542 0.953 rs9837341 chr3:49664767 A/G cg03060546 chr3:49711283 APEH -0.65 -5.72 -0.46 7.7e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7845219 0.544 rs6987400 chr8:95921295 T/C cg13393036 chr8:95962371 TP53INP1 -0.44 -5.14 -0.42 1.05e-6 Type 2 diabetes; TGCT cis rs75229567 0.618 rs11495622 chr12:70161286 G/A cg10114359 chr12:70132523 RAB3IP 1.35 6.71 0.52 6.17e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs12497850 0.864 rs4513485 chr3:49139966 G/A cg06212747 chr3:49208901 KLHDC8B 0.6 5.44 0.44 2.75e-7 Parkinson's disease; TGCT cis rs7945705 0.783 rs11042125 chr11:8938049 A/T cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -5.16 -0.42 9.67e-7 Hemoglobin concentration; TGCT cis rs7726839 0.794 rs11739663 chr5:594083 A/G cg09021430 chr5:549028 NA -0.41 -5.87 -0.47 3.65e-8 Obesity-related traits; TGCT cis rs9611565 0.729 rs169362 chr22:41827589 G/C cg06634786 chr22:41940651 POLR3H 0.81 7.71 0.57 3.43e-12 Vitiligo; TGCT cis rs35306767 0.855 rs11253468 chr10:903261 G/A cg26597838 chr10:835615 NA 0.75 10.61 0.69 4.13e-19 Eosinophil percentage of granulocytes; TGCT cis rs988712 0.672 rs16917237 chr11:27702383 A/C cg10635145 chr11:27742435 BDNF 0.42 5.7 0.46 8.44e-8 Obesity; TGCT cis rs951366 0.870 rs3747973 chr1:205677148 A/G cg24503407 chr1:205819492 PM20D1 0.43 5.08 0.42 1.34e-6 Menarche (age at onset); TGCT trans rs208520 0.586 rs208442 chr6:66900618 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -7.75 -0.57 2.86e-12 Exhaled nitric oxide output; TGCT cis rs17376456 0.569 rs6895356 chr5:93060781 A/G cg21475434 chr5:93447410 FAM172A 0.65 5.42 0.44 2.93e-7 Diabetic retinopathy; TGCT cis rs7666738 0.830 rs2865949 chr4:99039967 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs6089829 0.962 rs4997812 chr20:61663153 T/G cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9583531 0.891 rs61969072 chr13:111380701 T/G cg24331049 chr13:111365604 ING1 -0.76 -5.34 -0.43 4.34e-7 Coronary artery disease; TGCT cis rs910316 0.763 rs13712 chr14:75483812 T/C cg08847533 chr14:75593920 NEK9 0.84 9.12 0.63 1.69e-15 Height; TGCT cis rs9325144 0.505 rs6582691 chr12:38806894 T/C cg13010199 chr12:38710504 ALG10B -0.65 -5.48 -0.44 2.26e-7 Morning vs. evening chronotype; TGCT cis rs56104184 0.690 rs56312501 chr19:49395933 T/C cg21252483 chr19:49399788 TULP2 -0.28 -4.46 -0.37 1.8e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs12477438 0.798 rs6740035 chr2:99576578 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs4699052 0.928 rs10516502 chr4:104214616 A/G cg16532752 chr4:104119610 CENPE -0.53 -4.8 -0.4 4.42e-6 Testicular germ cell tumor; TGCT cis rs453301 0.658 rs6986044 chr8:8874786 G/C cg15556689 chr8:8085844 FLJ10661 -0.61 -5.05 -0.41 1.52e-6 Joint mobility (Beighton score); TGCT cis rs10504229 0.817 rs55949560 chr8:58167603 T/C cg24829409 chr8:58192753 C8orf71 -0.51 -4.93 -0.41 2.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs775227 0.574 rs34049435 chr3:113099499 C/T cg18753928 chr3:113234510 CCDC52 -0.64 -4.67 -0.39 7.75e-6 Dental caries; TGCT cis rs78487399 0.731 rs13395302 chr2:43706350 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.37 -0.43 3.75e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs8177253 1.000 rs6762719 chr3:133480817 A/G cg11941060 chr3:133502564 NA -0.29 -6.14 -0.48 1.02e-8 Iron status biomarkers; TGCT cis rs4953076 0.573 rs9973609 chr2:44450435 T/C cg00619915 chr2:44497795 NA -0.23 -5.08 -0.41 1.36e-6 Height; TGCT cis rs4819052 0.851 rs9977178 chr21:46664531 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11249608 0.636 rs13359572 chr5:178449276 T/C cg01312482 chr5:178451176 ZNF879 -0.58 -5.77 -0.46 5.94e-8 Pubertal anthropometrics; TGCT cis rs8177253 0.555 rs4481157 chr3:133464684 G/A cg24879335 chr3:133465180 TF 0.36 4.72 0.39 6.19e-6 Iron status biomarkers; TGCT cis rs3858526 0.959 rs11039540 chr11:5928334 C/T cg05234568 chr11:5960015 NA -0.44 -4.6 -0.38 1.03e-5 DNA methylation (variation); TGCT cis rs1153858 1.000 rs1288775 chr15:45661678 T/A cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs1865760 1.000 rs9393675 chr6:25930116 G/A cg17042849 chr6:26104293 HIST1H4C -0.5 -4.44 -0.37 2e-5 Height; TGCT cis rs3849570 0.615 rs6766011 chr3:81986136 G/A cg07356753 chr3:81810745 GBE1 -0.62 -5.43 -0.44 2.82e-7 Waist circumference;Body mass index; TGCT cis rs35934224 0.724 rs16984286 chr22:19858114 A/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.22 -0.42 7.16e-7 Glaucoma (primary open-angle); TGCT cis rs78456975 0.568 rs115482599 chr2:1571960 A/G cg12573674 chr2:1569213 NA -0.48 -5.13 -0.42 1.1e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs2832191 0.791 rs2832181 chr21:30481371 G/T cg24692254 chr21:30365293 RNF160 -0.95 -10.52 -0.69 7.06e-19 Dental caries; TGCT cis rs13064411 0.696 rs9860549 chr3:113148368 G/A cg18753928 chr3:113234510 CCDC52 -0.67 -5.12 -0.42 1.14e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs3096299 0.728 rs1011749 chr16:89510869 G/C cg06640241 chr16:89574553 SPG7 0.77 8.61 0.61 2.82e-14 Multiple myeloma (IgH translocation); TGCT cis rs9467711 0.606 rs9379852 chr6:26357278 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9309473 0.687 rs6706235 chr2:73613558 C/G cg20560298 chr2:73613845 ALMS1 -0.48 -5.39 -0.44 3.36e-7 Metabolite levels; TGCT cis rs67311347 0.910 rs7651204 chr3:40512835 C/T cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs9611565 0.729 rs203319 chr22:41914593 C/T cg06481639 chr22:41940642 POLR3H -0.63 -5.74 -0.46 6.81e-8 Vitiligo; TGCT cis rs10972341 1.000 rs10972341 chr9:35141705 C/T cg00812861 chr9:35114699 KIAA1539 -0.3 -4.46 -0.37 1.79e-5 Weight; TGCT cis rs9611565 0.512 rs715498 chr22:42148467 G/A cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs651907 0.535 rs1460097 chr3:101497569 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.86 0.4 3.51e-6 Colorectal cancer; TGCT cis rs9611565 0.512 rs8141103 chr22:42136930 T/C cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Vitiligo; TGCT cis rs1552244 1.000 rs76041173 chr3:10078695 G/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs12048904 0.541 rs1571046 chr1:101299216 T/C cg00063077 chr1:101360652 SLC30A7;EXTL2 0.82 7.43 0.56 1.5e-11 Multiple sclerosis; TGCT cis rs6690583 0.562 rs11588919 chr1:85442813 A/T cg20280350 chr1:85513789 MCOLN3 -0.69 -4.48 -0.37 1.68e-5 Serum sulfate level; TGCT trans rs3780486 0.846 rs6476402 chr9:33148552 G/A cg04842962 chr6:43655489 MRPS18A 1.18 14.79 0.8 3.8e-29 IgG glycosylation; TGCT cis rs10883723 0.775 rs2296579 chr10:104241375 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs35306767 0.903 rs11812523 chr10:915638 C/T cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs7589728 0.514 rs78204719 chr2:88460747 G/C cg04511125 chr2:88470314 THNSL2 0.72 5.94 0.47 2.71e-8 Plasma clusterin levels; TGCT cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.55 -5.66 -0.45 1e-7 Intelligence (multi-trait analysis); TGCT cis rs4953076 0.573 rs9973609 chr2:44450435 T/C cg04920474 chr2:44395004 PPM1B 0.6 6.02 0.48 1.81e-8 Height; TGCT cis rs9443645 0.901 rs9448596 chr6:79629429 T/C cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs6714788 0.503 rs1370356 chr2:100675241 G/C cg07810366 chr2:100720526 AFF3 -0.39 -5.57 -0.45 1.54e-7 Intelligence (multi-trait analysis); TGCT cis rs9527 0.535 rs4917999 chr10:104963051 C/G cg04362960 chr10:104952993 NT5C2 -0.73 -6.12 -0.48 1.11e-8 Arsenic metabolism; TGCT cis rs7267979 1.000 rs6115168 chr20:25372891 C/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2455799 0.613 rs2654654 chr3:15789242 C/T cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs1568889 1.000 rs34337978 chr11:28136746 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 9.0 0.63 3.18e-15 Bipolar disorder; TGCT cis rs2836974 0.644 rs9978775 chr21:40694526 A/G cg11890956 chr21:40555474 PSMG1 -0.72 -6.58 -0.51 1.21e-9 Cognitive function; TGCT cis rs3821902 0.646 rs56359789 chr3:64016911 T/C cg22134162 chr3:63841271 THOC7 -0.32 -4.73 -0.39 6.09e-6 Breast cancer; TGCT cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs61884328 0.584 rs74924988 chr11:47279765 G/A cg13308137 chr11:47528955 CUGBP1 0.42 5.82 0.46 4.68e-8 Total body bone mineral density (age over 60); TGCT cis rs9611519 0.639 rs7290458 chr22:41476337 C/T cg03806693 chr22:41940476 POLR3H 0.5 4.54 0.38 1.34e-5 Neuroticism; TGCT cis rs3858526 0.606 rs10838883 chr11:5952147 G/A cg24799795 chr11:5959658 NA 0.42 5.19 0.42 8.35e-7 DNA methylation (variation); TGCT cis rs2439831 0.867 rs2412780 chr15:43655794 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs1008375 0.966 rs4698642 chr4:17679174 A/T cg18681998 chr4:17616180 MED28 0.88 10.28 0.68 2.7e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs250677 0.687 rs168750 chr5:148446756 A/G cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs9733 0.621 rs6669122 chr1:150591732 A/G cg13175981 chr1:150552382 MCL1 0.53 6.08 0.48 1.39e-8 Tonsillectomy; TGCT cis rs9611565 0.503 rs5996062 chr22:42167464 C/G cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs9341808 0.935 rs9343974 chr6:80924645 A/G cg08355045 chr6:80787529 NA 0.27 4.68 0.39 7.39e-6 Sitting height ratio; TGCT cis rs10823500 0.549 rs10999204 chr10:72007306 G/A cg04118878 chr10:71993077 PPA1 0.57 5.4 0.44 3.27e-7 Blood protein levels; TGCT cis rs1865760 0.573 rs7450342 chr6:25919480 T/C cg03264133 chr6:25882463 NA -0.46 -4.72 -0.39 6.36e-6 Height; TGCT cis rs10838634 1.000 rs9735937 chr11:46809382 G/A cg18332754 chr11:46939436 LRP4 0.89 4.45 0.37 1.85e-5 Schizophrenia; TGCT cis rs79349575 0.783 rs17635252 chr17:47006950 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs9921192 1.000 rs251733 chr16:4321605 A/T cg00021532 chr16:4324280 TFAP4 0.84 9.73 0.66 5.68e-17 Prostate-specific antigen levels; TGCT cis rs9399135 0.967 rs11754783 chr6:135347661 T/A cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs2070488 0.965 rs4679060 chr3:38536261 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.87 -8.97 -0.63 3.85e-15 Electrocardiographic conduction measures; TGCT cis rs317689 0.690 rs547827 chr12:69669703 G/A cg14784868 chr12:69753453 YEATS4 0.53 4.51 0.38 1.5e-5 Response to diuretic therapy; TGCT cis rs28595532 0.920 rs114639588 chr4:119736176 T/C cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs2456568 0.802 rs1395386 chr11:93639331 A/G cg17595323 chr11:93583763 C11orf90 0.45 6.12 0.48 1.13e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs11105298 0.891 rs12369195 chr12:89934972 G/C cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.78e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9905704 0.647 rs12944274 chr17:57041293 C/G cg12560992 chr17:57184187 TRIM37 -0.58 -5.05 -0.41 1.53e-6 Testicular germ cell tumor; TGCT cis rs7172809 0.574 rs907398 chr15:77772003 G/A cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs875971 0.767 rs61348003 chr7:66005934 C/T cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs587847 0.895 rs28507799 chr15:37630205 A/G cg22444584 chr15:37174661 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs3008870 1.000 rs6673462 chr1:67461857 A/C cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs74400468 0.529 rs10128322 chr10:43206700 G/T cg05525499 chr10:43893015 HNRNPF -0.73 -4.81 -0.4 4.33e-6 Cannabis dependence symptom count; TGCT cis rs10131894 0.575 rs6574203 chr14:75429846 T/C cg08847533 chr14:75593920 NEK9 0.67 6.11 0.48 1.17e-8 Coronary artery disease; TGCT cis rs6866344 0.570 rs1079487 chr5:178136005 G/A cg03877680 chr5:178157825 ZNF354A 0.77 6.65 0.51 8.23e-10 Neutrophil percentage of white cells; TGCT cis rs1552244 0.572 rs3894321 chr3:10168892 A/C cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs1005224 0.927 rs1981899 chr14:76175594 G/A cg25116370 chr14:76127843 TTLL5;C14orf1 -0.61 -4.91 -0.4 2.79e-6 Large artery stroke; TGCT cis rs9486715 1.000 rs3798297 chr6:97062835 C/T cg06623918 chr6:96969491 KIAA0776 -1.08 -13.59 -0.77 2.61e-26 Headache; TGCT cis rs2880765 0.835 rs12324277 chr15:86041735 G/A cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs9467603 0.920 rs13213957 chr6:25786226 T/C cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Intelligence (multi-trait analysis); TGCT cis rs9549367 0.707 rs9549353 chr13:113843427 G/A cg09473364 chr13:112927190 NA -0.3 -4.6 -0.38 1.01e-5 Platelet distribution width; TGCT cis rs116095464 0.558 rs9687621 chr5:229194 C/T cg12570787 chr5:219185 SDHA;CCDC127 0.72 4.78 0.39 4.89e-6 Breast cancer; TGCT cis rs7513165 0.935 rs4951316 chr1:204161490 C/T cg12731349 chr1:204159619 KISS1 -0.49 -5.62 -0.45 1.19e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs7584330 0.868 rs7569197 chr2:238383073 A/G cg08992911 chr2:238395768 MLPH 0.64 5.13 0.42 1.07e-6 Prostate cancer; TGCT cis rs9487051 0.676 rs6913093 chr6:109636205 T/C cg01475377 chr6:109611718 NA -0.32 -4.86 -0.4 3.54e-6 Reticulocyte fraction of red cells; TGCT cis rs6988636 0.710 rs62521806 chr8:124161054 C/T cg22384356 chr8:124195192 FAM83A -0.39 -4.57 -0.38 1.19e-5 Urinary uromodulin levels; TGCT cis rs7959452 0.535 rs11615712 chr12:69619736 A/T cg11871910 chr12:69753446 YEATS4 -0.62 -6.08 -0.48 1.4e-8 Blood protein levels; TGCT cis rs2153535 0.580 rs6900007 chr6:8474035 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7582180 0.629 rs2309796 chr2:100954385 C/T cg14675211 chr2:100938903 LONRF2 0.53 5.16 0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs4891159 0.790 rs8087557 chr18:74116848 G/C cg24786174 chr18:74118243 ZNF516 -0.65 -10.7 -0.69 2.46e-19 Longevity; TGCT cis rs9906944 0.707 rs729003 chr17:47117775 C/T cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7829975 0.577 rs17684466 chr8:8545233 G/A cg06636001 chr8:8085503 FLJ10661 -0.61 -5.17 -0.42 9.06e-7 Mood instability; TGCT cis rs35146811 0.700 rs4729579 chr7:99780282 C/G cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs7209700 1.000 rs7209700 chr17:45351118 A/G cg17185639 chr17:45330862 ITGB3 0.18 4.57 0.38 1.15e-5 IgG glycosylation; TGCT cis rs3806843 0.547 rs246048 chr5:140327900 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs709400 0.643 rs11621777 chr14:104072090 A/G cg26031613 chr14:104095156 KLC1 1.15 16.05 0.82 4.72e-32 Body mass index; TGCT cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg15687855 chr3:44754131 ZNF502 0.52 6.31 0.49 4.59e-9 Depressive symptoms; TGCT cis rs6089829 0.888 rs4809467 chr20:61671688 A/G cg02380750 chr20:61661411 NA 0.35 5.68 0.45 9.19e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7940866 0.845 rs10894294 chr11:130830748 G/T cg12179176 chr11:130786555 SNX19 0.6 4.9 0.4 2.89e-6 Schizophrenia; TGCT cis rs68170813 0.563 rs6979198 chr7:107197694 T/G cg02696742 chr7:106810147 HBP1 -0.63 -5.19 -0.42 8.46e-7 Coronary artery disease; TGCT cis rs6540559 0.673 rs11805830 chr1:209984969 C/T cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs910316 1.000 rs175442 chr14:75603564 T/C cg08847533 chr14:75593920 NEK9 -0.94 -10.33 -0.68 2.03e-18 Height; TGCT cis rs644799 1.000 rs557079 chr11:95530125 C/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11098499 0.866 rs72676074 chr4:120359841 A/C cg09307838 chr4:120376055 NA 0.69 6.63 0.51 9.32e-10 Corneal astigmatism; TGCT cis rs7223966 1.000 rs9891018 chr17:61827856 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2594989 0.779 rs2443702 chr3:11586435 C/T cg00170343 chr3:11313890 ATG7 -0.68 -5.03 -0.41 1.65e-6 Circulating chemerin levels; TGCT cis rs6840360 1.000 rs1105535 chr4:152605170 A/G cg17479576 chr4:152424074 FAM160A1 -0.47 -4.87 -0.4 3.28e-6 Intelligence (multi-trait analysis); TGCT cis rs4563143 0.663 rs73025068 chr19:29238998 G/A cg04546413 chr19:29218101 NA 0.73 6.61 0.51 1.02e-9 Methadone dose in opioid dependence; TGCT cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs72781680 1.000 rs72796359 chr2:24160545 T/C cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.48 0.61 5.53e-14 Platelet count; TGCT cis rs12477438 0.520 rs1044575 chr2:99812070 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs155076 1.000 rs261404 chr13:21858162 T/G cg14456004 chr13:21872349 NA -1.27 -10.27 -0.68 2.79e-18 White matter hyperintensity burden; TGCT cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs34014631 0.786 rs74348615 chr10:103584682 G/A cg22630918 chr10:102748988 C10orf2 0.43 4.83 0.4 3.98e-6 Coronary artery calcification; TGCT cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg05738196 chr6:26577821 NA 0.88 11.13 0.71 2.26e-20 Intelligence (multi-trait analysis); TGCT cis rs7617773 1.000 rs12496784 chr3:48186267 C/T cg11946769 chr3:48343235 NME6 -0.61 -5.51 -0.44 2.02e-7 Coronary artery disease; TGCT cis rs9790314 0.543 rs1349352 chr3:161118486 C/T cg03342759 chr3:160939853 NMD3 -0.55 -5.7 -0.46 8.15e-8 Morning vs. evening chronotype; TGCT cis rs2204008 0.805 rs4589389 chr12:37946120 C/A cg26384229 chr12:38710491 ALG10B -0.7 -6.28 -0.49 5.12e-9 Bladder cancer; TGCT cis rs1153858 1.000 rs2461702 chr15:45647427 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs9787249 0.957 rs2274949 chr1:40221067 G/A cg20968010 chr1:40505947 CAP1 -0.5 -4.7 -0.39 6.72e-6 Blood protein levels; TGCT trans rs877282 0.755 rs11253399 chr10:790030 T/A cg22713356 chr15:30763199 NA 0.95 8.14 0.59 3.51e-13 Uric acid levels; TGCT trans rs6762477 0.748 rs11714286 chr3:50185508 G/A cg21659725 chr3:3221576 CRBN -0.68 -7.58 -0.56 6.91e-12 Menarche (age at onset); TGCT cis rs11209185 0.509 rs9326077 chr1:68452192 A/G cg22082780 chr1:68452167 NA 0.32 5.19 0.42 8.22e-7 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7618915 0.547 rs6762813 chr3:52726695 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs73635312 0.850 rs17506027 chr10:8995460 A/G cg20281962 chr10:8089733 NA -0.73 -4.43 -0.37 2.01e-5 Basal cell carcinoma; TGCT trans rs3780486 0.846 rs7873903 chr9:33142728 G/A cg04842962 chr6:43655489 MRPS18A 1.21 14.37 0.79 3.68e-28 IgG glycosylation; TGCT cis rs10089 0.904 rs2195921 chr5:127489754 A/C cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.27e-5 Ileal carcinoids; TGCT cis rs9556958 0.635 rs4529985 chr13:99167120 G/C cg07423050 chr13:99094983 FARP1 -0.23 -4.81 -0.4 4.37e-6 Educational attainment (years of education); TGCT cis rs2243480 0.808 rs12698508 chr7:65411958 A/T cg07424592 chr7:64974309 NA 1.32 8.15 0.59 3.39e-13 Diabetic kidney disease; TGCT cis rs6912958 0.781 rs9450712 chr6:88193175 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.54 -5.23 -0.43 7.03e-7 Monocyte percentage of white cells; TGCT cis rs611744 0.625 rs6469168 chr8:109288399 G/T cg21045802 chr8:109455806 TTC35 0.74 7.77 0.57 2.59e-12 Dupuytren's disease; TGCT cis rs6545977 1.000 rs6545977 chr2:63301164 G/A cg17519650 chr2:63277830 OTX1 -0.73 -7.85 -0.58 1.68e-12 Prostate cancer; TGCT cis rs7091068 0.662 rs829106 chr10:95441742 G/T cg20715218 chr10:95462985 C10orf4 0.49 4.49 0.37 1.61e-5 Urinary tract infection frequency; TGCT cis rs7584330 0.554 rs7582964 chr2:238385766 C/T cg08992911 chr2:238395768 MLPH -0.88 -5.15 -0.42 9.94e-7 Prostate cancer; TGCT cis rs950776 0.518 rs12916999 chr15:78826912 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs10411936 0.962 rs10402422 chr19:16475388 G/A cg19006008 chr19:16999768 F2RL3 0.29 5.02 0.41 1.74e-6 White blood cell count;Multiple sclerosis; TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs924607 0.583 rs12516251 chr5:608939 C/T cg18765565 chr5:669397 TPPP -0.48 -4.61 -0.38 9.96e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT trans rs1005277 0.579 rs2505240 chr10:38442419 G/T cg27523141 chr10:43048294 ZNF37B 0.74 8.61 0.61 2.7e-14 Extrinsic epigenetic age acceleration; TGCT cis rs11239930 0.538 rs17160592 chr1:146555193 T/C cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs2243480 0.908 rs2460431 chr7:65622846 A/G cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs8017423 0.967 rs11621045 chr14:90714003 C/T cg04374321 chr14:90722782 PSMC1 0.72 7.55 0.56 8.1e-12 Mortality in heart failure; TGCT cis rs28595532 0.764 rs115877991 chr4:119728298 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs10507380 0.824 rs77197829 chr13:27924604 G/T cg25543773 chr13:27185723 WASF3 0.32 4.52 0.38 1.45e-5 Electrocardiographic traits; TGCT cis rs1577917 1.000 rs955197 chr6:86729675 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.2 -0.42 7.94e-7 Response to antipsychotic treatment; TGCT cis rs5769707 0.967 rs9616327 chr22:50010891 G/A cg05373962 chr22:49881684 NA -0.3 -6.16 -0.48 9.42e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs5769707 0.609 rs739247 chr22:49996657 T/C cg05373962 chr22:49881684 NA -0.3 -5.16 -0.42 9.59e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2469997 0.858 rs1551785 chr8:120352397 T/A cg00681363 chr8:120844660 TAF2 0.65 4.45 0.37 1.9e-5 Hypertension (SNP x SNP interaction); TGCT cis rs2288278 0.543 rs11869101 chr17:46568013 T/G cg25032089 chr17:46643351 HOXB3 -0.41 -5.01 -0.41 1.86e-6 Hand grip strength; TGCT cis rs4953076 0.573 rs6738023 chr2:44405931 T/C cg00619915 chr2:44497795 NA -0.22 -5.01 -0.41 1.82e-6 Height; TGCT cis rs13242816 1.000 rs12672236 chr7:116111369 A/G cg02799643 chr7:116139180 CAV2 0.47 5.5 0.44 2.08e-7 P wave duration; TGCT cis rs7552404 0.889 rs380075 chr1:76106961 T/A cg22875332 chr1:76189707 ACADM -0.79 -9.72 -0.66 6.2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4689388 0.926 rs6446480 chr4:6295565 C/T cg25554036 chr4:6271136 WFS1 0.53 7.28 0.55 3.4e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9467773 1.000 rs2208331 chr6:26507319 A/G cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.962 rs3746747 chr20:61667631 T/C cg18188782 chr20:61659543 NA 0.44 5.36 0.43 3.87e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs896854 1.000 rs896854 chr8:95960511 T/C cg09323728 chr8:95962352 TP53INP1 -0.53 -6.88 -0.53 2.67e-10 Type 2 diabetes; TGCT cis rs1355223 0.583 rs2941041 chr11:34874734 A/C cg11058730 chr11:34937778 PDHX;APIP 0.78 8.67 0.61 2e-14 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs17401966 0.540 rs4846221 chr1:10472026 C/A cg19773385 chr1:10388646 KIF1B -0.22 -5.22 -0.42 7.29e-7 Hepatocellular carcinoma; TGCT cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg13607699 chr17:42295918 UBTF 0.59 5.31 0.43 4.88e-7 Total body bone mineral density; TGCT cis rs7829975 0.711 rs12682352 chr8:8646246 A/G cg06636001 chr8:8085503 FLJ10661 0.7 6.34 0.5 3.8e-9 Mood instability; TGCT cis rs62244186 0.748 rs6441861 chr3:44652287 A/G cg11003573 chr3:44754125 ZNF502 -0.41 -4.69 -0.39 6.98e-6 Depressive symptoms; TGCT cis rs4722166 0.573 rs35436671 chr7:22775508 G/A cg05265849 chr7:22767390 IL6 0.23 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs7824557 0.564 rs2572379 chr8:11237480 A/G cg21775007 chr8:11205619 TDH -0.65 -6.39 -0.5 3.07e-9 Retinal vascular caliber; TGCT cis rs765787 0.530 rs2899379 chr15:45534799 C/T cg24006582 chr15:45444508 DUOX1 0.24 5.25 0.43 6.52e-7 Uric acid levels; TGCT cis rs62185668 0.693 rs6077967 chr20:10919774 T/C cg17778165 chr20:10414372 MKKS -0.58 -4.53 -0.38 1.35e-5 Urinary bladder cancer; TGCT cis rs4595586 0.545 rs12826080 chr12:39387772 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs853679 0.517 rs9348794 chr6:28117757 T/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs3733585 0.699 rs4473653 chr4:9971058 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.68 -0.57 4.13e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7552404 1.000 rs9662166 chr1:76235906 C/A cg10523679 chr1:76189770 ACADM 0.9 9.48 0.65 2.34e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11792861 0.962 rs3829084 chr9:111801724 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.48 -4.45 -0.37 1.9e-5 Menarche (age at onset); TGCT cis rs4144743 0.938 rs35439279 chr17:45321694 C/T cg18085866 chr17:45331354 ITGB3 -0.7 -4.67 -0.39 7.69e-6 Body mass index; TGCT cis rs994533 0.674 rs12694416 chr2:218289497 A/C cg25097514 chr2:219157373 TMBIM1;PNKD -0.34 -4.46 -0.37 1.79e-5 Height; TGCT cis rs1375194 0.558 rs13418410 chr2:33800899 C/A cg04131969 chr2:33951647 MYADML -0.58 -5.22 -0.42 7.3e-7 Response to antidepressants in depression; TGCT cis rs73110464 0.505 rs2638503 chr12:53307369 C/G cg16329197 chr12:53359506 NA -0.31 -4.61 -0.38 9.68e-6 Cancer (pleiotropy); TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg18538332 chr22:24372958 LOC391322 0.84 7.23 0.54 4.44e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7666738 0.830 rs34412187 chr4:99010454 A/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs16957091 0.647 rs7176957 chr15:43336802 C/T cg17935677 chr15:44119062 WDR76 0.52 4.71 0.39 6.44e-6 MGMT methylation in smokers; TGCT cis rs9296092 0.517 rs6911036 chr6:33471652 C/G cg13560919 chr6:33536144 NA -0.22 -4.49 -0.37 1.6e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs9611565 0.592 rs5996037 chr22:41965292 A/G cg03806693 chr22:41940476 POLR3H -1.08 -11.36 -0.71 6.34e-21 Vitiligo; TGCT cis rs7809950 1.000 rs2237673 chr7:107131580 T/C cg23024343 chr7:107201750 COG5 -0.33 -5.32 -0.43 4.78e-7 Coronary artery disease; TGCT cis rs9653442 0.900 rs2309837 chr2:100837567 T/C cg22139774 chr2:100720529 AFF3 -0.39 -6.27 -0.49 5.59e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs17376456 0.542 rs1453003 chr5:93151611 T/C cg21475434 chr5:93447410 FAM172A -0.62 -5.06 -0.41 1.45e-6 Diabetic retinopathy; TGCT cis rs1843834 0.539 rs2068244 chr2:225440011 A/G cg12698349 chr2:225449008 CUL3 -0.78 -6.3 -0.49 4.75e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs9549260 0.785 rs2253001 chr13:41145330 A/T cg21288729 chr13:41239152 FOXO1 1.0 10.34 0.68 1.86e-18 Red blood cell count; TGCT cis rs12479064 0.724 rs2309618 chr2:99974473 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.74 -6.33 -0.49 4.06e-9 Chronic sinus infection; TGCT cis rs797680 0.786 rs555161 chr1:93676314 A/G cg17826107 chr1:92977322 EVI5 -0.24 -5.29 -0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs1005277 0.579 rs2474571 chr10:38384639 T/G cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.17e-14 Extrinsic epigenetic age acceleration; TGCT cis rs3849570 0.615 rs1851918 chr3:81980557 C/T cg07356753 chr3:81810745 GBE1 -0.61 -5.45 -0.44 2.61e-7 Waist circumference;Body mass index; TGCT cis rs1799949 0.965 rs11651623 chr17:41329847 G/A cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs7666738 0.830 rs1593569 chr4:99017485 C/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.65e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.808 rs6726917 chr2:43753913 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6831352 0.877 rs29001183 chr4:100056539 C/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs208520 0.690 rs12213928 chr6:66762978 G/A cg07460842 chr6:66804631 NA 0.96 10.32 0.68 2.1e-18 Exhaled nitric oxide output; TGCT cis rs854765 0.718 rs12943500 chr17:17790588 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.65 -6.47 -0.5 2.03e-9 Total body bone mineral density; TGCT cis rs1857353 0.901 rs17644957 chr1:75877394 A/G cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs4409675 0.576 rs10751724 chr1:28215631 C/T cg23691781 chr1:28212827 C1orf38 0.26 5.32 0.43 4.68e-7 Corneal astigmatism; TGCT cis rs9911578 0.900 rs717828 chr17:56535932 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.28 0.64 7.12e-16 Intelligence (multi-trait analysis); TGCT cis rs2075371 0.829 rs9641970 chr7:134004887 C/A cg11752832 chr7:134001865 SLC35B4 0.74 6.69 0.51 6.91e-10 Mean platelet volume; TGCT cis rs1061377 1.000 rs12646251 chr4:39134371 G/A cg24403649 chr4:39172243 NA 0.2 4.59 0.38 1.09e-5 Uric acid levels; TGCT cis rs12620999 0.941 rs10803654 chr2:238036570 C/T cg23555395 chr2:238036564 NA -0.31 -5.51 -0.44 2.02e-7 Systemic lupus erythematosus; TGCT cis rs35883536 0.626 rs11799819 chr1:101049382 G/A cg06223162 chr1:101003688 GPR88 -0.43 -8.04 -0.59 5.96e-13 Monocyte count; TGCT cis rs1552244 0.882 rs6443279 chr3:10053599 C/A cg00149659 chr3:10157352 C3orf10 0.78 4.99 0.41 2.04e-6 Alzheimer's disease; TGCT cis rs7072216 0.763 rs6584204 chr10:100173580 C/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs7552404 1.000 rs9662166 chr1:76235906 C/A cg03433033 chr1:76189801 ACADM 0.82 9.39 0.64 3.73e-16 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs2469997 0.925 rs2470011 chr8:120359937 G/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs921968 0.541 rs581013 chr2:219432040 G/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7267979 0.966 rs7270835 chr20:25435067 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4819052 0.851 rs4819039 chr21:46659458 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6696846 0.740 rs11240369 chr1:205115099 G/A cg03948781 chr1:205179583 DSTYK 0.34 4.47 0.37 1.72e-5 Red blood cell count; TGCT cis rs4665809 1.000 rs4665817 chr2:26305167 G/A cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs3540 0.512 rs3862437 chr15:91084632 A/G cg22089800 chr15:90895588 ZNF774 -0.74 -7.59 -0.56 6.78e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7647973 1.000 rs11130190 chr3:49402137 T/C cg07636037 chr3:49044803 WDR6 0.71 5.76 0.46 6.26e-8 Menarche (age at onset); TGCT cis rs2404602 0.632 rs34338978 chr15:77226805 T/C cg26408565 chr15:76604113 ETFA -0.37 -4.63 -0.38 9.04e-6 Blood metabolite levels; TGCT cis rs9467773 0.595 rs12525810 chr6:26623511 T/A cg02458000 chr6:26745757 NA 0.65 6.35 0.5 3.7e-9 Intelligence (multi-trait analysis); TGCT trans rs28595532 0.641 rs72670220 chr4:119300053 A/G cg26518628 chr1:97050305 NA -0.61 -7.34 -0.55 2.45e-11 Cannabis dependence symptom count; TGCT cis rs35160687 0.901 rs12472676 chr2:86510815 T/C cg03171300 chr2:86307199 POLR1A 0.32 5.52 0.44 1.88e-7 Night sleep phenotypes; TGCT cis rs3008870 1.000 rs2985795 chr1:67426223 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs644148 0.836 rs2686775 chr19:45000059 C/T cg15540054 chr19:45004280 ZNF180 -0.64 -5.25 -0.43 6.3e-7 Personality dimensions; TGCT cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg07341220 chr16:1583899 IFT140;TMEM204 -0.3 -4.7 -0.39 6.94e-6 Coronary artery disease; TGCT cis rs3015497 0.616 rs7152874 chr14:51046040 C/G cg04730355 chr14:51134070 SAV1 -0.62 -6.13 -0.48 1.07e-8 Mean platelet volume; TGCT cis rs6988636 1.000 rs9987357 chr8:124187620 T/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs3764400 0.567 rs67345313 chr17:46302201 T/C cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs7542091 0.704 rs2142907 chr1:210039505 T/C cg22029157 chr1:209979665 IRF6 0.65 6.3 0.49 4.63e-9 Monobrow; TGCT cis rs2075371 0.966 rs1646676 chr7:133999267 G/A cg11752832 chr7:134001865 SLC35B4 0.7 6.31 0.49 4.39e-9 Mean platelet volume; TGCT cis rs8032315 0.965 rs8027450 chr15:91418394 C/T cg05211768 chr15:91427848 FES 0.49 5.0 0.41 1.93e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6589563 0.609 rs10466589 chr11:116611985 G/A cg01124546 chr11:117515332 DSCAML1 -0.43 -4.68 -0.39 7.39e-6 Eosinophil counts; TGCT cis rs36051895 0.623 rs6476955 chr9:5256533 C/G cg02405213 chr9:5042618 JAK2 -0.7 -8.47 -0.61 5.88e-14 Pediatric autoimmune diseases; TGCT cis rs12908161 1.000 rs35960805 chr15:85343980 T/G cg11189052 chr15:85197271 WDR73 0.71 5.87 0.47 3.68e-8 Schizophrenia; TGCT cis rs903263 0.965 rs12756529 chr1:84664815 T/C cg09664975 chr1:84543551 PRKACB 0.48 4.53 0.38 1.39e-5 Breast cancer (male); TGCT cis rs7914558 0.902 rs3736922 chr10:104850632 A/G cg15744005 chr10:104629667 AS3MT 0.4 4.95 0.41 2.35e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1799949 1.000 rs11656097 chr17:41290613 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg18722847 chr3:44754129 ZNF502 -0.4 -4.49 -0.37 1.63e-5 Depressive symptoms; TGCT cis rs1552244 0.554 rs2272122 chr3:10047975 C/G cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs2663905 0.611 rs1509559 chr15:81391411 G/A cg09236163 chr15:81426669 C15orf26 -0.52 -5.58 -0.45 1.47e-7 QT interval (drug interaction); TGCT cis rs2455799 0.594 rs11928773 chr3:15925135 A/G cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.68e-6 Mean platelet volume; TGCT cis rs10892173 0.545 rs115865940 chr11:117666711 C/T cg21640587 chr11:117668038 DSCAML1 0.65 7.53 0.56 9.06e-12 Myopia; TGCT cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9942416 0.660 rs17563863 chr5:74998334 G/A cg19683494 chr5:74908142 NA 0.57 6.37 0.5 3.33e-9 Age-related disease endophenotypes; TGCT cis rs7091068 0.550 rs7079013 chr10:95487878 A/C cg20715218 chr10:95462985 C10orf4 0.5 5.95 0.47 2.59e-8 Urinary tract infection frequency; TGCT cis rs9611565 0.559 rs5758412 chr22:42080803 T/A cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Vitiligo; TGCT cis rs2836950 0.545 rs2836959 chr21:40623668 T/G cg06238570 chr21:40685208 BRWD1 -0.62 -6.33 -0.49 4.04e-9 Menarche (age at onset); TGCT cis rs6089584 0.888 rs6061981 chr20:60618973 T/C cg13770153 chr20:60521292 NA -0.54 -7.13 -0.54 7.45e-11 Body mass index; TGCT trans rs57221529 0.709 rs72707023 chr5:667620 G/A cg25482853 chr8:67687455 SGK3 1.2 10.45 0.68 1.03e-18 Lung disease severity in cystic fibrosis; TGCT cis rs9399135 0.967 rs6902954 chr6:135313994 C/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs477895 0.653 rs7939784 chr11:63910153 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.25 0.49 6.17e-9 Mean platelet volume; TGCT cis rs7660520 0.557 rs76004373 chr4:183731011 C/G cg04181038 chr4:183730758 NA 0.65 6.12 0.48 1.12e-8 Pediatric autoimmune diseases; TGCT cis rs2842992 0.830 rs2758313 chr6:160154099 C/G cg11366901 chr6:160182831 ACAT2 1.02 7.09 0.54 8.89e-11 Age-related macular degeneration (geographic atrophy); TGCT cis rs9787249 0.957 rs7547787 chr1:40220806 C/T cg20968010 chr1:40505947 CAP1 -0.48 -4.44 -0.37 2e-5 Blood protein levels; TGCT cis rs4478858 0.735 rs2271072 chr1:31840426 C/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.93 -0.41 2.55e-6 Alcohol dependence; TGCT cis rs11955175 1.000 rs75728011 chr5:40797505 A/C cg17351974 chr5:40835760 RPL37 0.87 5.92 0.47 2.98e-8 Bipolar disorder and schizophrenia; TGCT cis rs9393777 0.513 rs9368451 chr6:26654333 A/G cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.855 rs56222464 chr10:867535 C/G cg26597838 chr10:835615 NA 0.8 12.0 0.73 1.67e-22 Eosinophil percentage of granulocytes; TGCT cis rs10193935 0.901 rs222479 chr2:42656857 T/G cg27598129 chr2:42591480 NA -0.32 -4.75 -0.39 5.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg10802521 chr3:52805072 NEK4 -0.69 -8.09 -0.59 4.65e-13 Bipolar disorder; TGCT cis rs9926296 0.605 rs886952 chr16:89836781 G/A cg04287289 chr16:89883240 FANCA 0.91 11.66 0.72 1.15e-21 Vitiligo; TGCT cis rs28595532 0.920 rs114789346 chr4:119748652 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs1865760 0.865 rs9393677 chr6:25945815 G/A cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT cis rs79149102 0.579 rs7168638 chr15:75280826 T/C cg09165964 chr15:75287851 SCAMP5 -1.09 -6.08 -0.48 1.39e-8 Lung cancer; TGCT cis rs11204677 1 rs11204677 chr1:150574695 C/G cg13175981 chr1:150552382 MCL1 0.54 6.16 0.48 9.42e-9 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs10504229 1.000 rs67705655 chr8:58177688 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2130392 0.926 rs7679215 chr4:185635311 C/T cg14471096 chr4:185570637 CCDC111;CASP3 -0.52 -4.76 -0.39 5.33e-6 Kawasaki disease; TGCT cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs7552404 1.000 rs72686191 chr1:76218319 G/T cg03433033 chr1:76189801 ACADM 0.84 9.57 0.65 1.39e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7191700 0.836 rs12708722 chr16:11428905 T/A cg00044050 chr16:11439710 C16orf75 0.68 5.65 0.45 1.05e-7 Multiple sclerosis; TGCT cis rs11031096 0.655 rs1372806 chr11:4212308 C/T cg18678763 chr11:4115507 RRM1 -0.44 -5.69 -0.46 8.66e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs59586681 0.542 rs2064846 chr20:2233252 C/T cg04428163 chr20:1294021 SDCBP2 0.39 4.51 0.38 1.51e-5 Basal cell carcinoma; TGCT cis rs11098499 0.863 rs10009626 chr4:120470005 T/C cg09307838 chr4:120376055 NA 0.72 6.87 0.52 2.81e-10 Corneal astigmatism; TGCT cis rs2439831 0.850 rs28413704 chr15:44148427 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs35934224 0.783 rs12106549 chr22:19846987 G/T cg11182965 chr22:19864308 TXNRD2 -0.35 -4.8 -0.4 4.55e-6 Glaucoma (primary open-angle); TGCT cis rs35146811 0.695 rs858508 chr7:99821381 C/G cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs3734729 0.702 rs4870392 chr6:150566068 A/G cg16439130 chr6:149658548 MAP3K7IP2 0.47 4.85 0.4 3.58e-6 Pulmonary function;Pulmonary function (smoking interaction); TGCT cis rs7511006 0.858 rs2294402 chr22:50654428 T/G cg08875078 chr22:50639485 SELO 0.56 5.52 0.44 1.86e-7 Obesity-related traits; TGCT cis rs10791323 0.693 rs10750544 chr11:133718740 A/G cg15485101 chr11:133734466 NA 0.35 4.44 0.37 1.95e-5 Childhood ear infection; TGCT cis rs1008375 0.898 rs10008445 chr4:17593978 G/T cg10189774 chr4:17578691 LAP3 0.71 6.05 0.48 1.59e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4499344 0.526 rs8111902 chr19:33032243 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.64 -5.58 -0.45 1.44e-7 Mean platelet volume; TGCT cis rs782590 0.837 rs2627769 chr2:55927288 G/C cg03859395 chr2:55845619 SMEK2 0.84 9.73 0.66 5.7e-17 Metabolic syndrome; TGCT cis rs6964587 1.000 rs6969981 chr7:91689461 G/C cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs473651 0.967 rs483042 chr2:239335320 A/G cg08773314 chr2:239334832 ASB1 0.46 7.79 0.57 2.33e-12 Multiple system atrophy; TGCT cis rs9677476 0.516 rs1025107 chr2:232034342 C/T cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs7267979 0.934 rs2482913 chr20:25405086 T/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11247915 0.622 rs4072445 chr1:26664219 T/C cg23732845 chr1:26663426 AIM1L -0.37 -4.7 -0.39 6.89e-6 Obesity-related traits; TGCT cis rs2153535 0.580 rs7748455 chr6:8453625 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs7226408 0.948 rs1426755 chr18:34410831 A/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs1008375 0.931 rs7672369 chr4:17604825 A/G cg18681998 chr4:17616180 MED28 1.05 11.09 0.71 2.85e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.897 rs1062791 chr17:61896487 C/T cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.38e-6 Prudent dietary pattern; TGCT cis rs13427251 0.868 rs1901284 chr2:100146040 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 0.56 5.42 0.44 2.96e-7 Chronic sinus infection; TGCT trans rs208520 0.609 rs208436 chr6:66897470 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -7.75 -0.57 2.86e-12 Exhaled nitric oxide output; TGCT cis rs7707921 0.522 rs4703537 chr5:81480371 C/T cg15871215 chr5:81402204 ATG10 0.25 4.89 0.4 3.04e-6 Breast cancer; TGCT cis rs1552244 0.554 rs2272121 chr3:10047680 A/G cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs9972944 0.756 rs9907969 chr17:63754860 G/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.03 -0.41 1.65e-6 Total body bone mineral density; TGCT cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg17054783 chr10:134559939 INPP5A 0.24 4.83 0.4 3.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9807989 0.507 rs2041739 chr2:102994333 A/G cg03938978 chr2:103052716 IL18RAP -0.25 -5.01 -0.41 1.8e-6 Asthma; TGCT cis rs909002 0.849 rs10753257 chr1:32086089 G/A cg11573219 chr1:32083031 HCRTR1 -0.49 -6.39 -0.5 3.06e-9 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.571 rs4696279 chr4:152560449 G/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs10510102 0.872 rs11200269 chr10:123693536 A/G cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs9796 0.866 rs2176998 chr15:41420807 A/G cg18705301 chr15:41695430 NDUFAF1 -0.47 -6.2 -0.49 7.6e-9 Menopause (age at onset); TGCT cis rs12681288 0.712 rs2600488 chr8:1021266 A/C cg04851639 chr8:1020857 NA -0.37 -6.86 -0.52 2.92e-10 Schizophrenia; TGCT cis rs17384381 1.000 rs12128907 chr1:85891385 A/G cg16011679 chr1:85725395 C1orf52 0.8 6.44 0.5 2.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7178572 0.524 rs12904088 chr15:77399397 C/G cg15453836 chr15:77711506 NA -0.4 -4.54 -0.38 1.31e-5 Type 2 diabetes; TGCT cis rs137603 0.623 rs470075 chr22:39686806 G/A cg01093212 chr22:39715156 SNORD43;RPL3 -0.53 -4.85 -0.4 3.55e-6 Primary biliary cholangitis; TGCT cis rs6088580 0.634 rs1205336 chr20:32926336 G/A cg08999081 chr20:33150536 PIGU -0.24 -4.74 -0.39 5.68e-6 Glomerular filtration rate (creatinine); TGCT cis rs4654899 0.802 rs7517642 chr1:21252696 T/C cg01072550 chr1:21505969 NA -0.47 -7.06 -0.54 1.03e-10 Superior frontal gyrus grey matter volume; TGCT cis rs6598955 0.612 rs12738188 chr1:26548029 G/C cg04990556 chr1:26633338 UBXN11 -0.89 -11.55 -0.72 2.18e-21 Obesity-related traits; TGCT trans rs330048 0.545 rs11249913 chr8:9143521 G/T cg15556689 chr8:8085844 FLJ10661 -0.67 -6.96 -0.53 1.77e-10 Systemic lupus erythematosus; TGCT cis rs9858542 0.953 rs9827021 chr3:49514764 C/A cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2249625 0.523 rs2463707 chr6:72861732 G/A cg24401219 chr6:72892597 RIMS1 -0.54 -4.7 -0.39 6.92e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs12497850 0.931 rs7643368 chr3:48992855 T/G cg06212747 chr3:49208901 KLHDC8B 0.6 5.43 0.44 2.82e-7 Parkinson's disease; TGCT cis rs1215050 0.755 rs9991112 chr4:98651479 A/C cg05340658 chr4:99064831 C4orf37 -0.43 -5.4 -0.44 3.2e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs5750830 0.649 rs2413590 chr22:39790191 G/C cg24399712 chr22:39784796 NA -1.07 -12.53 -0.75 8.77e-24 Intelligence (multi-trait analysis); TGCT trans rs28735056 0.660 rs12454454 chr18:77674634 C/T cg05926928 chr17:57297772 GDPD1 -0.7 -6.79 -0.52 4.06e-10 Schizophrenia; TGCT cis rs6671200 1.000 rs259354 chr1:95718205 T/C cg20701556 chr1:95698924 RWDD3 -0.67 -5.63 -0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs295140 0.773 rs13007517 chr2:201129729 C/T cg04283868 chr2:201171347 SPATS2L 0.52 5.2 0.42 8.14e-7 QT interval; TGCT cis rs68170813 0.559 rs12537342 chr7:106943563 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs5750830 0.594 rs5757648 chr22:39775156 G/A cg24399712 chr22:39784796 NA -0.95 -11.01 -0.7 4.37e-20 Intelligence (multi-trait analysis); TGCT cis rs919433 0.617 rs700642 chr2:198600730 G/T cg00792783 chr2:198669748 PLCL1 -0.57 -5.32 -0.43 4.74e-7 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg27286337 chr10:134555280 INPP5A 0.4 4.86 0.4 3.52e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs62084913 0.511 rs895690 chr17:72784649 C/T cg25054828 chr17:72772726 NAT9;TMEM104 0.57 5.89 0.47 3.44e-8 Breast cancer; TGCT cis rs7523050 0.730 rs12734623 chr1:109442654 A/G cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs929354 0.772 rs6459737 chr7:156975136 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6725041 0.819 rs10175497 chr2:213082649 A/G cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT cis rs896854 0.902 rs726816 chr8:95968413 T/G cg23172400 chr8:95962367 TP53INP1 -0.38 -6.31 -0.49 4.42e-9 Type 2 diabetes; TGCT cis rs7208859 0.673 rs4131618 chr17:29204801 C/T cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12477438 0.520 rs11689265 chr2:99799267 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.05 13.31 0.77 1.16e-25 Chronic sinus infection; TGCT cis rs7208859 0.623 rs77009951 chr17:29080650 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4808199 0.847 rs34647936 chr19:19548239 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.69 4.99 0.41 1.98e-6 Nonalcoholic fatty liver disease; TGCT cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs17270561 0.525 rs10484432 chr6:26008876 G/A cg16482183 chr6:26056742 HIST1H1C 0.97 7.36 0.55 2.21e-11 Iron status biomarkers; TGCT cis rs9733 0.650 rs11204684 chr1:150608894 A/G cg13175981 chr1:150552382 MCL1 0.51 5.75 0.46 6.61e-8 Tonsillectomy; TGCT cis rs60154123 0.505 rs76101197 chr1:210044089 T/C cg22029157 chr1:209979665 IRF6 0.79 5.78 0.46 5.6e-8 Coronary artery disease; TGCT cis rs76419734 0.850 rs72673889 chr4:106810547 A/G cg24545054 chr4:106630052 GSTCD;INTS12 1.01 4.61 0.38 9.7e-6 Post bronchodilator FEV1; TGCT cis rs7017914 0.840 rs13254851 chr8:71689034 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs4819052 0.851 rs2838848 chr21:46671017 A/G cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2549003 0.870 rs10053046 chr5:131821558 A/G cg21138405 chr5:131827807 IRF1 0.19 4.79 0.4 4.64e-6 Asthma (sex interaction); TGCT cis rs9443645 0.901 rs9361480 chr6:79724429 C/T cg09184832 chr6:79620586 NA -0.5 -5.58 -0.45 1.46e-7 Intelligence (multi-trait analysis); TGCT cis rs6063312 0.518 rs6122718 chr20:47346225 A/G cg18078177 chr20:47281410 PREX1 -0.38 -4.63 -0.38 9e-6 Tonometry; TGCT cis rs6582630 0.519 rs11609739 chr12:38547969 G/A cg26384229 chr12:38710491 ALG10B 0.85 7.75 0.57 2.91e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs778371 0.723 rs12999865 chr2:233627250 T/C cg08000102 chr2:233561755 GIGYF2 0.72 8.68 0.61 1.91e-14 Schizophrenia; TGCT cis rs259282 0.605 rs36107586 chr19:33109674 G/A cg26639809 chr19:33781782 NA 0.23 4.53 0.38 1.39e-5 Schizophrenia; TGCT cis rs8038465 0.662 rs57771618 chr15:73967578 T/C cg15420318 chr15:73925796 NPTN 0.71 7.52 0.56 9.44e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs644799 1.000 rs12291986 chr11:95523030 T/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2153535 0.546 rs9378559 chr6:8539058 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.6 0.45 1.33e-7 Motion sickness; TGCT cis rs6484504 0.576 rs11031323 chr11:31245413 T/G cg14844989 chr11:31128820 NA -0.23 -4.51 -0.38 1.47e-5 Red blood cell count; TGCT cis rs2032447 0.670 rs198845 chr6:26107790 A/C cg03264133 chr6:25882463 NA -0.52 -4.76 -0.39 5.32e-6 Intelligence (multi-trait analysis); TGCT cis rs367615 0.918 rs13173339 chr5:108871318 T/A cg17395555 chr5:108820864 NA 0.29 4.71 0.39 6.59e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg07157834 chr1:205819609 PM20D1 0.44 7.03 0.53 1.21e-10 Menarche (age at onset); TGCT cis rs7666738 0.753 rs13120995 chr4:98972762 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs763121 0.853 rs4821809 chr22:39065743 G/C cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs4699052 0.739 rs1607094 chr4:104225413 G/A cg16532752 chr4:104119610 CENPE -0.5 -4.73 -0.39 5.91e-6 Testicular germ cell tumor; TGCT cis rs28595532 0.920 rs17324821 chr4:119770716 A/G cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs9807989 0.839 rs3755276 chr2:102978459 C/T cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs523522 0.962 rs509445 chr12:121017243 A/C cg27279351 chr12:120934652 DYNLL1 0.76 6.43 0.5 2.51e-9 High light scatter reticulocyte count; TGCT cis rs6570726 0.846 rs439035 chr6:145887990 G/C cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs9926296 0.681 rs12923946 chr16:89821080 C/T cg04287289 chr16:89883240 FANCA 0.68 6.86 0.52 2.83e-10 Vitiligo; TGCT cis rs6674176 1.000 rs11210937 chr1:44405563 T/C cg12908607 chr1:44402522 ARTN -0.82 -9.42 -0.65 3.12e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7267979 1.000 rs6037086 chr20:25306338 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1008375 1.000 rs10440301 chr4:17663199 G/A cg10189774 chr4:17578691 LAP3 0.53 4.68 0.39 7.26e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6460942 0.659 rs13247187 chr7:12551851 T/C cg06484146 chr7:12443880 VWDE -0.53 -4.92 -0.4 2.66e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs9995386 chr4:98907826 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.32 0.49 4.21e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4665809 0.838 rs2243834 chr2:26357748 A/C cg04944784 chr2:26401820 FAM59B 0.61 6.02 0.48 1.87e-8 Gut microbiome composition (summer); TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.54 -5.36 -0.43 3.83e-7 Prudent dietary pattern; TGCT cis rs7617773 0.817 rs11707606 chr3:48237087 A/C cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs1801251 0.711 rs778339 chr2:233739678 T/C cg25237894 chr2:233734115 C2orf82 -0.29 -5.61 -0.45 1.23e-7 Coronary artery disease; TGCT cis rs9443645 0.901 rs1572585 chr6:79690576 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs11239930 0.538 rs4950362 chr1:146559883 A/G cg00044796 chr1:146552390 NA -0.35 -4.5 -0.37 1.54e-5 AIDS progression; TGCT cis rs10465746 0.714 rs12730621 chr1:84433745 C/G cg10977910 chr1:84465055 TTLL7 0.69 7.04 0.53 1.14e-10 Obesity-related traits; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs617219 0.698 rs12189248 chr5:78517143 A/G cg23987322 chr5:78407566 BHMT -0.37 -4.94 -0.41 2.48e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1862618 0.853 rs252922 chr5:56136343 G/T cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs2180341 1.000 rs9401950 chr6:127655485 C/T cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs11190604 1.000 rs11190552 chr10:102206607 G/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9467773 1.000 rs9393731 chr6:26529374 C/T cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg11062466 chr8:58055876 NA 0.42 4.46 0.37 1.84e-5 Developmental language disorder (linguistic errors); TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg21237687 chr17:6899380 ALOX12 0.54 5.72 0.46 7.41e-8 Tonsillectomy; TGCT cis rs2243480 1.000 rs464895 chr7:65527106 A/G cg07424592 chr7:64974309 NA 1.35 7.62 0.56 5.53e-12 Diabetic kidney disease; TGCT trans rs2469997 0.858 rs2470007 chr8:120358833 T/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT trans rs629535 0.773 rs681534 chr8:70056964 A/C cg21567404 chr3:27674614 NA 0.56 8.82 0.62 8.75e-15 Dupuytren's disease; TGCT cis rs6570726 0.935 rs425731 chr6:145834151 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs769267 0.965 rs12460764 chr19:19431963 G/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg07636037 chr3:49044803 WDR6 0.95 10.21 0.68 3.98e-18 Parkinson's disease; TGCT cis rs7089973 0.604 rs7904188 chr10:116610271 G/C cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs2456568 1.000 rs2456568 chr11:93691332 A/T cg16099599 chr11:93583650 C11orf90 -0.39 -4.86 -0.4 3.48e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4851266 1.000 rs12619178 chr2:100838157 C/T cg07810366 chr2:100720526 AFF3 -0.37 -5.33 -0.43 4.53e-7 Educational attainment; TGCT cis rs593982 0.920 rs487264 chr11:65481465 A/C cg08755490 chr11:65554678 OVOL1 1.27 7.71 0.57 3.56e-12 Atopic dermatitis; TGCT cis rs4689592 0.546 rs10937784 chr4:7060935 G/C cg06697600 chr4:7070879 GRPEL1 -0.43 -4.46 -0.37 1.81e-5 Monocyte percentage of white cells; TGCT cis rs2535633 0.631 rs2710326 chr3:52995444 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.56 5.29 0.43 5.37e-7 Body mass index; TGCT trans rs459571 0.715 rs401826 chr9:136890591 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.71 -7.53 -0.56 9.17e-12 Platelet distribution width; TGCT cis rs1891275 0.508 rs2096079 chr10:93496667 C/G cg07889827 chr10:93443413 NA -0.32 -6.8 -0.52 4e-10 Intelligence (multi-trait analysis); TGCT cis rs12048904 0.505 rs11166511 chr1:101240686 G/C cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.78 -6.84 -0.52 3.2e-10 Multiple sclerosis; TGCT cis rs2797780 1.000 rs2776882 chr6:37508075 T/C cg00985040 chr6:37553208 NA 0.24 4.77 0.39 5.04e-6 Systemic lupus erythematosus; TGCT cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg20887711 chr4:1340912 KIAA1530 0.91 8.34 0.6 1.22e-13 Longevity; TGCT cis rs873946 0.564 rs12772704 chr10:134557318 G/A cg27286337 chr10:134555280 INPP5A 0.41 4.9 0.4 2.97e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs60154123 0.505 rs1319435 chr1:210047618 C/T cg21951975 chr1:209979733 IRF6 -0.65 -4.72 -0.39 6.19e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs7696715 chr4:98938486 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg11062466 chr8:58055876 NA 0.43 4.58 0.38 1.11e-5 Developmental language disorder (linguistic errors); TGCT cis rs4819052 0.851 rs10470247 chr21:46659018 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.78 0.52 4.27e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1577917 1.000 rs1577919 chr6:86757296 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.2 -0.42 8.12e-7 Response to antipsychotic treatment; TGCT cis rs7528684 0.779 rs7529060 chr1:157725264 T/G cg17134153 chr1:157670328 FCRL3 -0.26 -4.58 -0.38 1.11e-5 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs651907 0.737 rs9844218 chr3:101584983 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 -0.63 -6.66 -0.51 8.05e-10 Colorectal cancer; TGCT cis rs17601876 0.623 rs1062033 chr15:51547938 C/G cg19946085 chr15:51559439 CYP19A1 -0.34 -4.84 -0.4 3.73e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs514406 0.505 rs7543239 chr1:53162416 A/G cg22166914 chr1:53195759 ZYG11B 0.44 7.64 0.57 5.13e-12 Monocyte count; TGCT cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg26818010 chr10:134567672 INPP5A -0.36 -4.82 -0.4 4.08e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs16866061 1.000 rs72974269 chr2:225454907 C/T cg12698349 chr2:225449008 CUL3 1.0 9.4 0.64 3.62e-16 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs62064224 0.614 rs8065246 chr17:30682274 T/C cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.66e-6 Schizophrenia; TGCT cis rs3020333 0.875 rs3020334 chr6:152012956 A/G cg22157087 chr6:152012887 ESR1 0.19 4.65 0.39 8.27e-6 Total body bone mineral density; TGCT cis rs13108904 0.935 rs922698 chr4:1282722 C/T cg00684032 chr4:1343700 KIAA1530 -0.22 -4.73 -0.39 6.06e-6 Obesity-related traits; TGCT cis rs2072499 0.898 rs2758609 chr1:156202868 G/A cg25208724 chr1:156163844 SLC25A44 0.97 10.22 0.68 3.76e-18 Testicular germ cell tumor; TGCT cis rs4950928 0.887 rs7556099 chr1:203166198 C/G cg17014757 chr1:203156097 CHI3L1 -0.36 -4.56 -0.38 1.22e-5 YKL-40 levels; TGCT cis rs12210905 0.920 rs9379975 chr6:27295808 T/A cg08851530 chr6:28072375 NA 1.29 5.45 0.44 2.65e-7 Hip circumference adjusted for BMI; TGCT cis rs597539 0.652 rs513615 chr11:68705504 G/T cg06028808 chr11:68637592 NA 0.54 6.88 0.53 2.63e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2224391 0.628 rs2753237 chr6:5252675 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.49 -0.5 1.9e-9 Height; TGCT cis rs6430585 0.941 rs60963894 chr2:136539670 T/G cg07169764 chr2:136633963 MCM6 0.89 7.96 0.58 9.17e-13 Corneal structure; TGCT cis rs9926296 0.656 rs2376881 chr16:89827011 C/G cg27121462 chr16:89883253 FANCA 0.57 5.41 0.44 3.15e-7 Vitiligo; TGCT cis rs28386778 0.897 rs2665797 chr17:61922485 C/G cg06873352 chr17:61820015 STRADA -0.58 -6.3 -0.49 4.66e-9 Prudent dietary pattern; TGCT cis rs12681288 0.550 rs72507624 chr8:961324 G/A cg04851639 chr8:1020857 NA -0.29 -4.76 -0.39 5.27e-6 Schizophrenia; TGCT cis rs8031584 0.958 rs61997079 chr15:31238271 G/C cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.29e-6 Huntington's disease progression; TGCT cis rs9894429 0.683 rs112612275 chr17:79552604 C/A cg21984481 chr17:79567631 NPLOC4 0.26 4.83 0.4 3.98e-6 Eye color traits; TGCT cis rs921943 0.554 rs163132 chr5:78285921 A/G cg18828365 chr5:78281819 ARSB 0.35 4.6 0.38 1.05e-5 Blood and toenail selenium levels;Blood trace element (Se levels); TGCT cis rs1580019 0.961 rs4460271 chr7:32496503 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs1008375 0.544 rs56227066 chr4:17565713 G/A cg10189774 chr4:17578691 LAP3 0.58 5.32 0.43 4.76e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs36051895 0.632 rs10815164 chr9:5131312 T/A cg02405213 chr9:5042618 JAK2 -0.71 -9.55 -0.65 1.57e-16 Pediatric autoimmune diseases; TGCT cis rs2439831 0.867 rs11856184 chr15:43919162 A/C cg19166733 chr15:44192098 FRMD5 -0.24 -4.89 -0.4 3.08e-6 Lung cancer in ever smokers; TGCT cis rs9810089 0.872 rs527888 chr3:136031358 G/C cg12473912 chr3:136751656 NA 0.35 4.91 0.4 2.77e-6 Gestational age at birth (child effect); TGCT cis rs7647973 0.961 rs62259943 chr3:49425167 A/G cg07636037 chr3:49044803 WDR6 -0.72 -5.7 -0.46 8.28e-8 Menarche (age at onset); TGCT cis rs7147624 0.938 rs10467734 chr14:65913947 C/T cg03016385 chr14:66212404 NA -0.5 -7.18 -0.54 5.64e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6684514 1.000 rs3806409 chr1:156252291 A/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs4268898 0.760 rs4665675 chr2:24468132 C/T cg02683114 chr2:24398427 C2orf84 -0.21 -4.87 -0.4 3.39e-6 Asthma; TGCT cis rs3818285 0.515 rs12258440 chr10:111676799 C/T cg00817464 chr10:111662876 XPNPEP1 -0.32 -5.51 -0.44 2.03e-7 Superior crus of antihelix expression; TGCT cis rs3771570 0.901 rs62190413 chr2:242417950 G/A cg21155796 chr2:242212141 HDLBP 0.92 6.63 0.51 9.25e-10 Prostate cancer; TGCT cis rs8017423 0.967 rs2277516 chr14:90722824 G/C cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs13064411 0.696 rs7624994 chr3:113228009 T/C cg10517650 chr3:113235015 CCDC52 -0.32 -4.45 -0.37 1.85e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs66561647 0.661 rs35851359 chr8:128935626 G/C cg11792826 chr8:129160931 MIR1208 0.21 4.87 0.4 3.38e-6 Hemoglobin concentration; TGCT cis rs7833790 1.000 rs7833384 chr8:82730915 T/C cg23324259 chr8:82754387 SNX16 -0.65 -4.49 -0.37 1.59e-5 Diastolic blood pressure; TGCT cis rs882732 0.576 rs10139508 chr14:95035399 A/G cg24754598 chr14:95966488 NA 0.24 4.64 0.38 8.75e-6 Blood protein levels; TGCT cis rs10504229 1.000 rs67594249 chr8:58180521 T/A cg08219700 chr8:58056026 NA 0.3 4.55 0.38 1.25e-5 Developmental language disorder (linguistic errors); TGCT cis rs61524473 1 rs61524473 chr15:45646283 T/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Metabolite levels (small molecules and protein measures); TGCT cis rs7582180 0.790 rs13020451 chr2:100927131 T/G cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs6546537 1.000 rs17036866 chr2:69857711 T/C cg10773587 chr2:69614142 GFPT1 -0.77 -6.5 -0.5 1.79e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs3796352 1.000 rs11712653 chr3:53070875 A/C cg07884673 chr3:53033167 SFMBT1 -0.62 -7.53 -0.56 9.25e-12 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4325129 0.651 rs11265220 chr1:159494324 T/C cg07417683 chr1:159440267 NA 0.37 4.64 0.38 8.54e-6 Obesity-related traits; TGCT cis rs7172809 0.561 rs76746801 chr15:77789773 C/T cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs10791097 0.547 rs3829271 chr11:130753912 T/A cg12179176 chr11:130786555 SNX19 0.86 10.31 0.68 2.26e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs1008375 0.931 rs7672369 chr4:17604825 A/G cg10189774 chr4:17578691 LAP3 0.65 5.53 0.44 1.84e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs950776 0.518 rs12910100 chr15:78822667 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT trans rs9329221 0.741 rs58689676 chr8:9806492 T/C cg15556689 chr8:8085844 FLJ10661 -0.82 -7.76 -0.57 2.7e-12 Neuroticism; TGCT cis rs6089584 0.927 rs2296083 chr20:60574216 C/T cg16423285 chr20:60520624 NA -0.63 -6.97 -0.53 1.66e-10 Body mass index; TGCT cis rs992157 0.764 rs13020391 chr2:219184436 C/T cg00012203 chr2:219082015 ARPC2 -0.74 -6.77 -0.52 4.62e-10 Colorectal cancer; TGCT cis rs7615952 0.866 rs13063119 chr3:125643847 G/A cg05084668 chr3:125655381 ALG1L -0.76 -6.21 -0.49 7.3e-9 Blood pressure (smoking interaction); TGCT cis rs12049351 0.774 rs11805194 chr1:229631734 T/C cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs28386778 0.863 rs2251164 chr17:61884120 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs6840360 0.593 rs867800 chr4:152691470 T/C cg17479576 chr4:152424074 FAM160A1 -0.53 -5.26 -0.43 5.99e-7 Intelligence (multi-trait analysis); TGCT cis rs11627546 0.528 rs61980573 chr14:70362467 G/A cg10496350 chr14:71275911 MAP3K9 -1.01 -4.93 -0.41 2.54e-6 Red blood cell traits; TGCT cis rs597539 0.652 rs584108 chr11:68630282 A/T cg06028808 chr11:68637592 NA -0.52 -6.74 -0.52 5.39e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1933488 0.931 rs9397587 chr6:153416912 G/A cg24028809 chr6:153414101 RGS17 0.21 4.67 0.39 7.69e-6 Prostate cancer; TGCT cis rs9341808 0.667 rs3828753 chr6:80912746 C/T cg08355045 chr6:80787529 NA 0.3 4.98 0.41 2.07e-6 Sitting height ratio; TGCT cis rs7917772 0.636 rs1475644 chr10:104491164 G/A cg05855489 chr10:104503620 C10orf26 -0.66 -5.31 -0.43 5e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10464366 0.571 rs13233049 chr7:39187536 C/T cg15212455 chr7:39170539 POU6F2 0.3 6.73 0.52 5.66e-10 IgG glycosylation; TGCT cis rs611744 0.870 rs613179 chr8:109166006 G/A cg21045802 chr8:109455806 TTC35 0.69 6.06 0.48 1.51e-8 Dupuytren's disease; TGCT trans rs3780486 0.846 rs73484568 chr9:33132492 G/A cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs9948 0.737 rs878064 chr2:97438552 G/C cg01990225 chr2:97406019 LMAN2L -0.79 -4.96 -0.41 2.27e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs735396 0.770 rs2257764 chr12:121446446 T/A cg02403541 chr12:121454288 C12orf43 -0.77 -7.48 -0.56 1.16e-11 N-glycan levels; TGCT cis rs7647973 0.560 rs7638154 chr3:49299375 C/A cg06212747 chr3:49208901 KLHDC8B 0.67 6.36 0.5 3.57e-9 Menarche (age at onset); TGCT cis rs9486715 0.867 rs4839842 chr6:96955387 A/T cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs7826238 0.564 rs2921053 chr8:8319963 G/C cg15556689 chr8:8085844 FLJ10661 0.73 6.9 0.53 2.38e-10 Systolic blood pressure; TGCT cis rs9921338 0.961 rs4315353 chr16:11414160 T/C cg00044050 chr16:11439710 C16orf75 0.95 7.39 0.55 1.92e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9326248 0.911 rs474339 chr11:117059552 G/A cg16524733 chr11:117070046 TAGLN 0.33 4.95 0.41 2.33e-6 Blood protein levels; TGCT cis rs11209185 0.527 rs11209186 chr1:68434340 A/G cg22082780 chr1:68452167 NA -0.31 -4.66 -0.39 8.01e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs2153535 0.580 rs1932281 chr6:8473765 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs12477438 0.734 rs4851184 chr2:99666434 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs7937682 0.632 rs3944619 chr11:111774743 A/G cg09085632 chr11:111637200 PPP2R1B 0.84 7.34 0.55 2.4e-11 Primary sclerosing cholangitis; TGCT cis rs9300255 0.596 rs11057202 chr12:123720775 G/T cg00376283 chr12:123451042 ABCB9 0.79 6.72 0.52 6e-10 Neutrophil percentage of white cells; TGCT cis rs7829975 0.711 rs4481596 chr8:8704330 G/C cg08975724 chr8:8085496 FLJ10661 0.56 5.04 0.41 1.6e-6 Mood instability; TGCT cis rs6500602 0.702 rs11076834 chr16:4549583 C/G cg08645402 chr16:4508243 NA 0.19 5.23 0.43 6.9e-7 Schizophrenia; TGCT cis rs447921 0.861 rs4789297 chr17:74447351 G/T cg09812376 chr17:74270190 QRICH2 -0.42 -4.54 -0.38 1.29e-5 Mitochondrial DNA levels; TGCT cis rs155076 1.000 rs564685 chr13:21846879 A/G cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs7666738 0.830 rs11727612 chr4:99001662 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7926906 0.715 rs7127256 chr11:90525490 C/T cg26138821 chr11:89956704 CHORDC1 0.49 5.03 0.41 1.69e-6 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs3008870 1.000 rs3008894 chr1:67377739 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.08 11.27 0.71 1.02e-20 Lymphocyte percentage of white cells; TGCT trans rs783396 0.685 rs67667413 chr6:107086560 G/A cg27564810 chr2:201635376 AOX2P 0.5 6.61 0.51 1e-9 Stroke; TGCT cis rs67311347 1.000 rs7641495 chr3:40494690 T/C cg13683864 chr3:40499215 RPL14 1.16 12.09 0.74 1.04e-22 Renal cell carcinoma; TGCT cis rs7208859 0.623 rs11650271 chr17:29213943 C/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7089973 0.565 rs7082836 chr10:116646237 G/A cg03647239 chr10:116582469 FAM160B1 0.55 5.04 0.41 1.64e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs12681287 0.752 rs4463401 chr8:87250309 C/T cg27223183 chr8:87520930 FAM82B -0.8 -5.67 -0.45 9.58e-8 Caudate activity during reward; TGCT cis rs2836974 0.897 rs2836929 chr21:40543811 T/C cg11890956 chr21:40555474 PSMG1 1.13 12.1 0.74 1e-22 Cognitive function; TGCT cis rs951366 0.903 rs823116 chr1:205720483 G/A cg24503407 chr1:205819492 PM20D1 0.42 5.17 0.42 9.1e-7 Menarche (age at onset); TGCT cis rs7647973 0.626 rs4855845 chr3:49687043 T/C cg03060546 chr3:49711283 APEH 0.65 5.7 0.46 8.3e-8 Menarche (age at onset); TGCT cis rs7917772 0.503 rs7896841 chr10:104294665 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs62244186 0.659 rs56234157 chr3:44516221 G/A cg10108389 chr3:44770937 ZNF501 -0.48 -4.97 -0.41 2.13e-6 Depressive symptoms; TGCT cis rs9902453 0.765 rs2264302 chr17:28057095 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.39 -0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs8070740 0.841 rs2189337 chr17:5326178 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs644799 1.000 rs623191 chr11:95548359 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs16867321 0.588 rs1919156 chr2:181456978 C/T cg23363182 chr2:181467187 NA -0.41 -6.04 -0.48 1.69e-8 Obesity; TGCT cis rs9467773 0.967 rs9461267 chr6:26525455 T/G cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs61990749 0.597 rs17106157 chr14:78146878 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.65 -0.39 8.45e-6 Fibroblast growth factor basic levels; TGCT cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg15687855 chr3:44754131 ZNF502 -0.46 -5.54 -0.45 1.69e-7 Depressive symptoms; TGCT cis rs8031584 0.918 rs34331396 chr15:31248736 C/G cg08704250 chr15:31115839 NA -0.36 -4.98 -0.41 2.07e-6 Huntington's disease progression; TGCT cis rs8180040 0.701 rs7625067 chr3:47095305 T/C cg27129171 chr3:47204927 SETD2 0.74 9.79 0.66 4.15e-17 Colorectal cancer; TGCT cis rs6951245 0.706 rs28483034 chr7:1170171 C/A cg03188948 chr7:1209495 NA 0.63 5.71 0.46 7.71e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9381040 0.655 rs9381031 chr6:41044957 A/T cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs72781680 0.898 rs17462670 chr2:24026579 T/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs2535633 0.631 rs2710314 chr3:52969128 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.54 4.88 0.4 3.22e-6 Body mass index; TGCT cis rs826838 0.935 rs1601579 chr12:39178606 G/C cg13010199 chr12:38710504 ALG10B 0.78 6.16 0.48 9.26e-9 Heart rate; TGCT cis rs2153535 0.542 rs9393012 chr6:8439809 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs66887589 0.616 rs11732621 chr4:120212883 A/C cg24670566 chr4:120433619 PDE5A 0.21 4.61 0.38 9.68e-6 Diastolic blood pressure; TGCT cis rs11651000 0.857 rs16947078 chr17:45825500 A/G cg06532163 chr17:45867833 NA 0.37 5.23 0.43 6.97e-7 IgG glycosylation; TGCT cis rs8077577 0.895 rs6502640 chr17:18122485 G/A cg09161412 chr17:18057145 MYO15A -0.6 -4.79 -0.4 4.61e-6 Obesity-related traits; TGCT cis rs2204008 0.506 rs11495470 chr12:38026904 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.9 0.4 2.88e-6 Bladder cancer; TGCT cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg20887711 chr4:1340912 KIAA1530 -0.76 -6.57 -0.51 1.22e-9 Longevity; TGCT cis rs3806843 0.900 rs2563279 chr5:140131535 G/A cg19875535 chr5:140030758 IK -0.36 -5.96 -0.47 2.41e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs6543140 0.964 rs1035126 chr2:103019981 C/T cg09003973 chr2:102972529 NA 0.57 4.8 0.4 4.45e-6 Blood protein levels; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg00024416 chr22:24240387 NA -0.25 -4.84 -0.4 3.81e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9359856 0.564 rs72915904 chr6:90421412 C/A cg13799429 chr6:90582589 CASP8AP2 -0.48 -4.51 -0.38 1.49e-5 Bipolar disorder; TGCT cis rs909674 0.662 rs2899318 chr22:39837625 A/G cg05872129 chr22:39784769 NA -0.98 -9.4 -0.65 3.51e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs11785400 0.793 rs11785012 chr8:143748355 G/A cg10596483 chr8:143751796 JRK 0.55 5.34 0.43 4.27e-7 Schizophrenia; TGCT cis rs9640161 0.789 rs10952250 chr7:150025966 T/C cg17279839 chr7:150038598 RARRES2 0.43 4.66 0.39 7.91e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg02073558 chr3:44770973 ZNF501 0.57 5.66 0.45 9.81e-8 Depressive symptoms; TGCT cis rs7552404 1.000 rs11161521 chr1:76216330 T/C cg10523679 chr1:76189770 ACADM 0.89 9.53 0.65 1.72e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6893807 0.778 rs1501673 chr5:87963600 G/A cg24804195 chr5:87968844 LOC645323 0.82 5.14 0.42 1.03e-6 Body mass index; TGCT cis rs6754311 0.593 rs313522 chr2:136430866 T/A cg07169764 chr2:136633963 MCM6 0.65 5.79 0.46 5.38e-8 Mosquito bite size; TGCT cis rs9527 0.590 rs2274339 chr10:104860053 T/A cg04362960 chr10:104952993 NT5C2 0.68 5.82 0.46 4.81e-8 Arsenic metabolism; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg04234412 chr22:24373322 LOC391322 -0.91 -10.4 -0.68 1.31e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6049375 1.000 rs6036628 chr20:24044396 A/G cg14741141 chr20:24973699 C20orf3 0.74 4.67 0.39 7.81e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs514406 0.825 rs6695819 chr1:53223366 T/C cg16325326 chr1:53192061 ZYG11B -0.71 -8.82 -0.62 8.9e-15 Monocyte count; TGCT cis rs3087591 0.664 rs2525565 chr17:29666588 T/C cg24425628 chr17:29625626 OMG;NF1 0.39 5.56 0.45 1.57e-7 Hip circumference; TGCT cis rs7432375 0.610 rs60574021 chr3:136520281 C/G cg15507776 chr3:136538369 TMEM22 0.55 5.63 0.45 1.15e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs17331151 0.505 rs35325270 chr3:52556369 C/T cg15956490 chr3:53032818 SFMBT1 0.63 4.8 0.4 4.48e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg07092213 chr7:1199455 ZFAND2A -0.48 -5.53 -0.44 1.83e-7 Longevity;Endometriosis; TGCT cis rs59107033 0.607 rs12496583 chr3:123121286 C/T cg04890266 chr3:123102914 ADCY5 0.36 5.36 0.43 3.9e-7 Lymphocyte counts; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg25703541 chr22:24373054 LOC391322 0.81 8.47 0.61 5.88e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17030434 0.953 rs10014299 chr4:154700858 A/G cg14289246 chr4:154710475 SFRP2 -0.95 -7.52 -0.56 9.48e-12 Electrocardiographic conduction measures; TGCT cis rs595982 0.510 rs3826817 chr19:49401444 C/T cg21252483 chr19:49399788 TULP2 -0.29 -5.12 -0.42 1.13e-6 Red cell distribution width; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg12419862 chr22:24373484 LOC391322 -0.79 -8.23 -0.59 2.19e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2153535 0.580 rs4960411 chr6:8438231 C/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg18538332 chr22:24372958 LOC391322 -1.02 -13.36 -0.77 9.13e-26 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7659604 0.517 rs56311153 chr4:122729685 T/C cg19748678 chr4:122722346 EXOSC9 0.9 9.34 0.64 4.9e-16 Type 2 diabetes; TGCT cis rs6570726 0.935 rs369214 chr6:145856709 G/A cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs752590 0.720 rs2305132 chr2:113956941 T/A cg27425262 chr2:113953981 PSD4;LOC440839 0.4 4.63 0.38 9.02e-6 Mucinous ovarian carcinoma; TGCT cis rs78456975 1.000 rs6730391 chr2:1566838 A/C cg01028140 chr2:1542097 TPO -0.33 -4.54 -0.38 1.29e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs3796352 1.000 rs4478072 chr3:53106125 G/T cg07884673 chr3:53033167 SFMBT1 0.57 6.03 0.48 1.78e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11605924 0.934 rs7945565 chr11:45878992 A/G ch.11.939596F chr11:45881766 CRY2 -0.38 -4.61 -0.38 9.73e-6 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs7095607 0.813 rs7905259 chr10:69926610 A/C cg18986048 chr10:69913749 MYPN 0.44 5.03 0.41 1.68e-6 Lung function (FVC); TGCT cis rs2832191 0.755 rs2832192 chr21:30491173 G/T cg08807101 chr21:30365312 RNF160 -0.62 -5.79 -0.46 5.38e-8 Dental caries; TGCT cis rs497273 0.517 rs580240 chr12:121199903 T/G cg02419362 chr12:121203948 SPPL3 0.19 4.52 0.38 1.43e-5 Systemic lupus erythematosus; TGCT cis rs2033711 0.936 rs7257999 chr19:58964860 C/G cg04608855 chr19:58913158 NA 0.61 5.93 0.47 2.86e-8 Uric acid clearance; TGCT cis rs877282 0.945 rs11599043 chr10:777972 C/T cg17470449 chr10:769945 NA 0.31 5.02 0.41 1.76e-6 Uric acid levels; TGCT cis rs7772486 0.875 rs2814873 chr6:146308932 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.5 0.65 2.02e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7833790 0.724 rs10958045 chr8:82722994 T/C cg17211192 chr8:82754475 SNX16 -0.95 -8.83 -0.62 8.45e-15 Diastolic blood pressure; TGCT cis rs6840360 0.615 rs12647465 chr4:152607318 C/A cg22705602 chr4:152727874 NA -0.32 -5.44 -0.44 2.71e-7 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.728 rs6923230 chr6:88213949 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs597539 0.518 rs35093305 chr11:68730729 A/G cg21862992 chr11:68658383 NA 0.45 6.11 0.48 1.21e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg00024416 chr22:24240387 NA -0.26 -4.93 -0.4 2.61e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10782582 0.609 rs1630302 chr1:76412090 A/T cg03433033 chr1:76189801 ACADM -0.52 -5.06 -0.41 1.44e-6 Daytime sleep phenotypes; TGCT trans rs6089829 0.855 rs6090205 chr20:61665269 A/G cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9910055 0.762 rs4239142 chr17:42205876 A/G cg13607699 chr17:42295918 UBTF -0.83 -7.37 -0.55 2.14e-11 Total body bone mineral density; TGCT cis rs3741404 0.931 rs594942 chr11:64006292 T/C cg19570321 chr11:63258214 HRASLS5 -0.45 -5.18 -0.42 8.76e-7 Platelet count; TGCT cis rs4888262 0.545 rs4243108 chr16:74692453 A/G cg01733217 chr16:74700730 RFWD3 -0.74 -7.5 -0.56 1.05e-11 Testicular germ cell tumor; TGCT trans rs74976893 1.000 rs2429935 chr17:69719420 A/G cg25743221 chr6:152501416 SYNE1 0.94 6.78 0.52 4.46e-10 Response to abacavir-containing treatment in HIV-1 infection (virologic failure);Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs3774830 0.748 rs7698146 chr4:5465476 G/A cg26943120 chr4:5472116 STK32B 0.22 4.82 0.4 4.15e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2070997 0.715 rs11244164 chr9:133736116 A/G cg01000188 chr9:133769184 QRFP 0.26 4.49 0.37 1.59e-5 Response to amphetamines; TGCT cis rs2594989 1.000 rs2594989 chr3:11316143 C/T cg00170343 chr3:11313890 ATG7 0.67 5.23 0.42 7.12e-7 Circulating chemerin levels; TGCT cis rs2404602 0.647 rs11631959 chr15:77040048 T/C cg23625390 chr15:77176239 SCAPER -0.38 -4.79 -0.39 4.75e-6 Blood metabolite levels; TGCT cis rs7267979 0.727 rs4815431 chr20:25532405 T/C cg03522245 chr20:25566470 NINL -0.56 -5.79 -0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6570726 0.738 rs6925594 chr6:145898454 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.904 rs12600751 chr17:37553651 G/C cg15445000 chr17:37608096 MED1 -0.36 -5.09 -0.42 1.31e-6 Glomerular filtration rate (creatinine); TGCT trans rs1499614 1.000 rs2707838 chr7:66159201 C/T cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.65 -6.18 -0.49 8.55e-9 Bipolar disorder; TGCT cis rs72615157 0.628 rs7801070 chr7:99847147 T/G cg00814883 chr7:100076585 TSC22D4 -0.58 -5.56 -0.45 1.57e-7 Lung function (FEV1/FVC); TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg10150615 chr22:24372951 LOC391322 0.84 7.28 0.55 3.42e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2745967 0.529 rs658347 chr1:208058924 C/T cg22525895 chr1:207977042 MIR29B2 -0.36 -5.65 -0.45 1.03e-7 Resting heart rate; TGCT cis rs1552244 0.572 rs68121641 chr3:10165845 T/A cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs8072100 0.846 rs6503796 chr17:45765249 T/C cg08085267 chr17:45401833 C17orf57 -0.49 -5.3 -0.43 5.16e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs8017423 0.967 rs2277515 chr14:90723000 A/G cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs77633900 0.614 rs2439982 chr15:76925071 T/G cg21673338 chr15:77095150 SCAPER -0.5 -4.82 -0.4 4.07e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs2019137 0.836 rs4848318 chr2:113953952 T/C cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.53e-13 Lymphocyte counts; TGCT cis rs6671200 1.000 rs76064624 chr1:95661033 A/G cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs950169 1.000 rs12903820 chr15:84723820 A/G cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.14e-8 Schizophrenia; TGCT cis rs7824557 0.707 rs3808518 chr8:11143272 A/C cg21775007 chr8:11205619 TDH -0.6 -5.79 -0.46 5.49e-8 Retinal vascular caliber; TGCT cis rs2236918 0.687 rs1776176 chr1:242012554 C/T cg04158730 chr1:242011433 EXO1 0.57 5.31 0.43 4.82e-7 Menopause (age at onset); TGCT cis rs9611565 0.570 rs12159188 chr22:42121125 A/T cg06634786 chr22:41940651 POLR3H 0.86 8.54 0.61 4.12e-14 Vitiligo; TGCT cis rs11711311 1.000 rs2242109 chr3:113434100 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs9677476 0.608 rs6437005 chr2:232055735 A/G cg07929768 chr2:232055508 NA 0.35 5.64 0.45 1.09e-7 Food antigen IgG levels; TGCT cis rs6582630 0.519 rs11181998 chr12:38439970 C/A cg13010199 chr12:38710504 ALG10B 0.59 4.79 0.4 4.67e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6951245 0.706 rs28522260 chr7:1183964 C/A cg27454412 chr7:1067447 C7orf50 0.56 4.5 0.37 1.55e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3806843 0.576 rs246043 chr5:140330924 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6740731 0.518 rs35766785 chr2:145295628 C/T cg07679370 chr2:145795797 NA 0.29 5.63 0.45 1.14e-7 Coronary artery disease; TGCT cis rs9534288 0.700 rs9316178 chr13:46570449 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs9913156 0.789 rs56003988 chr17:4600764 G/A cg00122941 chr17:4613640 ARRB2 0.88 7.63 0.57 5.46e-12 Lymphocyte counts; TGCT cis rs4455778 0.580 rs4275185 chr7:49114615 C/G cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.07e-9 Lung cancer in never smokers; TGCT cis rs2574985 0.530 rs4935727 chr10:52277400 G/A cg12753529 chr10:51525504 NA 0.23 4.67 0.39 7.62e-6 Subjective well-being; TGCT cis rs4372836 0.504 rs3768666 chr2:29005870 C/T cg09522027 chr2:28974177 PPP1CB -0.56 -5.65 -0.45 1.06e-7 Body mass index; TGCT cis rs4148883 0.504 rs2000864 chr4:100123776 A/C cg12011299 chr4:100065546 ADH4 0.36 4.99 0.41 1.95e-6 Alcohol dependence; TGCT cis rs804280 0.564 rs4639 chr8:11644751 A/G cg26752888 chr8:11627280 NEIL2 -0.56 -5.16 -0.42 9.44e-7 Myopia (pathological); TGCT cis rs1865760 0.534 rs2032444 chr6:26046744 T/G cg17691542 chr6:26056736 HIST1H1C 0.71 5.55 0.45 1.69e-7 Height; TGCT cis rs11785400 0.793 rs1137521 chr8:143739162 C/T cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT trans rs9951602 0.512 rs12607612 chr18:76651799 G/A cg02800362 chr5:177631904 HNRNPAB 1.14 12.9 0.76 1.17e-24 Obesity-related traits; TGCT cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg27211696 chr2:191398769 TMEM194B 0.28 5.28 0.43 5.54e-7 Pulse pressure; TGCT cis rs1903068 0.853 rs12331597 chr4:55997914 T/C cg09978860 chr4:56023921 NA 0.59 6.55 0.51 1.38e-9 Endometriosis; TGCT trans rs210152 0.588 rs210131 chr6:33535466 T/C cg08795360 chr21:41033440 B3GALT5 -0.47 -7.42 -0.55 1.59e-11 Schizophrenia; TGCT cis rs72634258 0.572 rs66692705 chr1:7938565 T/C cg26816564 chr1:7831052 VAMP3 0.65 4.98 0.41 2.11e-6 Inflammatory bowel disease; TGCT cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg22535103 chr8:58192502 C8orf71 -0.4 -5.13 -0.42 1.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs911555 0.570 rs752624 chr14:104020454 T/C cg26031613 chr14:104095156 KLC1 0.57 5.19 0.42 8.39e-7 Intelligence (multi-trait analysis); TGCT cis rs7818688 0.697 rs77402106 chr8:95970484 C/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg07617317 chr6:118971624 C6orf204 0.51 5.52 0.44 1.92e-7 Diastolic blood pressure; TGCT cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg06108461 chr20:60628389 TAF4 -0.75 -11.02 -0.7 4.27e-20 Body mass index; TGCT cis rs12780845 0.505 rs10795462 chr10:17245119 A/C cg01003015 chr10:17271136 VIM -0.63 -5.69 -0.46 8.67e-8 Homocysteine levels; TGCT cis rs17270561 1.000 rs17270561 chr6:25820439 A/C cg16482183 chr6:26056742 HIST1H1C -0.77 -5.23 -0.43 6.93e-7 Iron status biomarkers; TGCT cis rs10791097 0.547 rs1050078 chr11:130746146 T/C cg14779329 chr11:130786720 SNX19 0.29 4.79 0.4 4.58e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs947211 0.846 rs708726 chr1:205762139 G/T cg11965913 chr1:205819406 PM20D1 -0.44 -4.8 -0.4 4.41e-6 Parkinson's disease; TGCT cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs3770081 1.000 rs11899576 chr2:86256193 G/A cg23655155 chr2:86332777 POLR1A;PTCD3 -1.18 -4.81 -0.4 4.33e-6 Facial emotion recognition (sad faces); TGCT trans rs561341 1.000 rs501957 chr17:30314504 C/T cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs612683 0.599 rs2809823 chr1:101003762 C/A cg09408571 chr1:101003634 GPR88 0.3 4.77 0.39 5.1e-6 Breast cancer; TGCT cis rs2688482 0.557 rs2550236 chr3:195522321 A/G cg13752114 chr3:195489708 MUC4 0.32 4.71 0.39 6.56e-6 Lung disease severity in cystic fibrosis; TGCT cis rs12908161 0.959 rs12908699 chr15:85240403 G/T cg12863693 chr15:85201151 NMB 0.46 5.53 0.44 1.79e-7 Schizophrenia; TGCT cis rs3008870 1.000 rs12117131 chr1:67451922 C/T cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs17253792 0.822 rs8009239 chr14:56062490 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6688613 0.685 rs2142615 chr1:166922731 G/C cg07049167 chr1:166818506 POGK 0.25 5.13 0.42 1.08e-6 Refractive astigmatism; TGCT cis rs910316 0.737 rs108621 chr14:75480637 T/C cg11812906 chr14:75593930 NEK9 -0.58 -5.41 -0.44 3.16e-7 Height; TGCT cis rs17253792 0.822 rs78429067 chr14:56092551 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs916888 0.773 rs169201 chr17:44790203 A/G cg17911788 chr17:44343683 NA -0.65 -6.61 -0.51 1.04e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2370759 1.000 rs79487858 chr10:32616405 T/C cg01819863 chr10:32635814 EPC1 1.03 10.0 0.67 1.27e-17 Sexual dysfunction (female); TGCT cis rs1167827 1.000 rs1167827 chr7:75163169 A/G cg09919756 chr7:75617850 TMEM120A -0.21 -4.61 -0.38 1e-5 Body mass index;BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4776059 1.000 rs62023352 chr15:52889448 T/C cg25063058 chr15:52860530 ARPP19 0.54 4.81 0.4 4.23e-6 Schizophrenia; TGCT cis rs8177253 1.000 rs8177261 chr3:133480588 A/C cg11941060 chr3:133502564 NA -0.29 -6.14 -0.48 1.02e-8 Iron status biomarkers; TGCT trans rs57221529 0.766 rs12522140 chr5:587261 C/A cg11887960 chr12:57824829 NA 1.14 9.3 0.64 6.29e-16 Lung disease severity in cystic fibrosis; TGCT trans rs7726839 0.507 rs60068988 chr5:597668 T/C cg11887960 chr12:57824829 NA 1.2 9.56 0.65 1.47e-16 Obesity-related traits; TGCT cis rs2288278 0.601 rs11652125 chr17:46597109 T/G cg25032089 chr17:46643351 HOXB3 -0.42 -5.01 -0.41 1.86e-6 Hand grip strength; TGCT cis rs6674176 0.597 rs6671164 chr1:44403489 G/T cg13606994 chr1:44402422 ARTN -0.48 -5.19 -0.42 8.24e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs12620999 0.774 rs2875726 chr2:237954576 T/C cg23555395 chr2:238036564 NA 0.26 4.56 0.38 1.21e-5 Systemic lupus erythematosus; TGCT cis rs8111998 0.826 rs10418805 chr19:22765991 A/G cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs614226 1.000 rs580016 chr12:120933977 T/C cg17541002 chr12:121714889 CAMKK2 0.24 4.46 0.37 1.83e-5 Type 1 diabetes nephropathy; TGCT cis rs7267979 0.789 rs6083820 chr20:25354178 G/A cg13486641 chr20:25479848 NINL 0.16 4.57 0.38 1.17e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs904251 0.772 rs1224127 chr6:37417556 G/A cg01843034 chr6:37503916 NA -0.44 -4.52 -0.38 1.43e-5 Cognitive performance; TGCT cis rs1670533 0.697 rs658846 chr4:1084723 G/C cg27284194 chr4:1044797 NA 0.64 5.09 0.42 1.26e-6 Recombination rate (females); TGCT cis rs6740322 0.857 rs11690012 chr2:43542480 C/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.71 -0.52 6.14e-10 Coronary artery disease; TGCT cis rs4631830 0.863 rs57263518 chr10:51519154 A/G cg10326726 chr10:51549505 MSMB -0.26 -5.27 -0.43 5.78e-7 Prostate-specific antigen levels; TGCT cis rs2836974 0.932 rs6517527 chr21:40581751 G/A cg11890956 chr21:40555474 PSMG1 1.1 11.97 0.73 2e-22 Cognitive function; TGCT cis rs8062405 0.824 rs28772958 chr16:28535305 A/G cg09754948 chr16:28834200 ATXN2L 0.63 5.01 0.41 1.79e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs908922 0.676 rs4112785 chr1:152533115 G/C cg20991723 chr1:152506922 NA 0.44 5.91 0.47 3.08e-8 Hair morphology; TGCT cis rs9952991 0.709 rs11874945 chr18:12754775 T/C cg23598886 chr18:12777645 NA -0.65 -4.66 -0.39 8.08e-6 Inflammatory skin disease; TGCT cis rs288326 0.561 rs74869113 chr2:183858306 C/T cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT trans rs2688608 0.592 rs10824032 chr10:75528130 G/A cg13918328 chr10:52500089 ASAH2B 0.68 6.81 0.52 3.67e-10 Inflammatory bowel disease; TGCT cis rs7945705 0.902 rs2016942 chr11:8938787 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.49 5.52 0.44 1.89e-7 Hemoglobin concentration; TGCT cis rs7104764 0.957 rs6598075 chr11:207275 C/G cg18336825 chr11:236787 PSMD13;SIRT3 -0.99 -10.18 -0.67 4.61e-18 Menarche (age at onset); TGCT cis rs858239 0.539 rs2178140 chr7:23191625 G/C cg05602783 chr7:23145260 KLHL7 -0.63 -4.98 -0.41 2.09e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs10032931 0.962 rs10030217 chr4:96457804 A/T cg03008707 chr4:96468962 UNC5C -0.33 -4.48 -0.37 1.65e-5 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs73198271 0.563 rs74556999 chr8:8548459 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.31 -5.1 -0.42 1.25e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs3809566 0.676 rs62013179 chr15:63329601 T/G cg08198488 chr15:63333792 TPM1 -0.33 -4.97 -0.41 2.15e-6 Platelet count; TGCT cis rs903263 0.901 rs11163908 chr1:84597803 A/T cg09664975 chr1:84543551 PRKACB 0.5 4.67 0.39 7.62e-6 Breast cancer (male); TGCT cis rs10791097 0.667 rs1893019 chr11:130756664 C/G cg12179176 chr11:130786555 SNX19 0.83 9.92 0.67 1.94e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9309473 0.607 rs7567343 chr2:73596605 C/A cg20560298 chr2:73613845 ALMS1 -0.41 -4.54 -0.38 1.31e-5 Metabolite levels; TGCT cis rs7666738 0.830 rs1876192 chr4:98727555 T/C cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9549367 0.774 rs9549696 chr13:113875062 C/T cg18105134 chr13:113819100 PROZ -0.31 -5.29 -0.43 5.41e-7 Platelet distribution width; TGCT cis rs460214 0.564 rs464519 chr21:40024182 A/G cg05519781 chr21:40033154 ERG -0.53 -4.55 -0.38 1.24e-5 Response to cognitive-behavioural therapy in anxiety disorder; TGCT cis rs7809950 1.000 rs2712214 chr7:107188031 G/A cg23024343 chr7:107201750 COG5 -0.35 -5.4 -0.44 3.21e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs34212748 chr4:99068708 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10858047 0.883 rs6701882 chr1:115181249 C/T cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs12510870 0.598 rs12643650 chr4:74408727 G/A cg05868023 chr4:75230803 EREG 0.56 5.14 0.42 1.06e-6 Iris color (b* coordinate); TGCT cis rs763014 0.932 rs2269559 chr16:682297 T/C cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.12e-6 Height; TGCT cis rs2153904 0.793 rs12564209 chr1:205720212 C/G cg23034840 chr1:205782522 SLC41A1 -0.82 -4.97 -0.41 2.19e-6 Prostate-specific antigen levels; TGCT cis rs858239 0.669 rs1006709 chr7:23140099 C/T cg00469287 chr7:23338798 C7orf30 0.42 4.5 0.38 1.51e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs9646954 0.542 rs4149510 chr2:101023635 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.76 0.39 5.2e-6 Intelligence (multi-trait analysis); TGCT cis rs55794721 0.509 rs909834 chr1:25757996 A/G cg10117171 chr1:25599238 RHD -0.34 -5.63 -0.45 1.15e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs2235642 0.891 rs2281231 chr16:1601879 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.27 -4.66 -0.39 8.15e-6 Coronary artery disease; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg25703541 chr22:24373054 LOC391322 -0.94 -11.48 -0.72 3.07e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7618915 0.547 rs4687636 chr3:52633929 G/A cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs9302001 0.626 rs9561696 chr13:95469626 A/G cg07483244 chr13:95358924 NA -0.36 -4.56 -0.38 1.19e-5 Panic disorder; TGCT cis rs9674544 0.757 rs4410130 chr17:47122942 C/T cg20966754 chr17:47091339 IGF2BP1 0.45 4.99 0.41 2.02e-6 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs7547997 0.615 rs716221 chr1:158303872 C/T cg07950803 chr1:158223934 CD1A 0.31 4.68 0.39 7.4e-6 QRS duration; TGCT cis rs769267 0.895 rs2965189 chr19:19519518 G/T cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.28 0.43 5.61e-7 Tonsillectomy; TGCT cis rs9467711 0.523 rs9379853 chr6:26357635 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4938534 0.785 rs1944926 chr11:111287287 T/G cg24049888 chr11:111250129 POU2AF1 -0.26 -4.54 -0.38 1.3e-5 Primary biliary cholangitis; TGCT trans rs17685 0.725 rs4728548 chr7:75654632 A/T cg19862616 chr7:65841803 NCRNA00174 -0.47 -6.97 -0.53 1.65e-10 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7617773 0.817 rs17786132 chr3:48249420 C/G cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs2243480 1.000 rs1499614 chr7:65730798 A/T cg07424592 chr7:64974309 NA 1.31 7.72 0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs6964587 1.000 rs6952671 chr7:91597934 C/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs933688 1.000 rs2367526 chr5:90740525 A/G cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.03 8.74 0.62 1.33e-14 Smoking behavior; TGCT cis rs9308731 1.000 rs6542334 chr2:111907214 G/A cg04202892 chr2:111875749 ACOXL 0.42 4.52 0.38 1.45e-5 Chronic lymphocytic leukemia; TGCT cis rs7103648 1.000 rs11039225 chr11:47430599 G/A cg20307385 chr11:47447363 PSMC3 1.02 12.61 0.75 5.75e-24 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs701145 0.938 rs1086056 chr3:154088411 T/G cg17054900 chr3:154042577 DHX36 0.49 4.48 0.37 1.69e-5 Coronary artery disease; TGCT trans rs877282 0.945 rs10904550 chr10:774177 C/T cg22713356 chr15:30763199 NA 1.11 9.86 0.66 2.79e-17 Uric acid levels; TGCT cis rs1696756 0.877 rs2587500 chr17:77827362 A/T cg00646381 chr17:77835854 NA 0.43 6.11 0.48 1.21e-8 Glucocorticoid-induced osteonecrosis (age 10 years and older); TGCT cis rs3796352 0.527 rs11714793 chr3:52924930 A/G cg15956490 chr3:53032818 SFMBT1 0.47 5.4 0.44 3.27e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6424115 0.760 rs2999566 chr1:24051124 A/G cg15997130 chr1:24165203 NA 0.67 6.31 0.49 4.56e-9 Immature fraction of reticulocytes; TGCT cis rs10504229 0.593 rs1442127 chr8:57992136 T/C cg08280861 chr8:58055591 NA 0.34 4.69 0.39 7.23e-6 Developmental language disorder (linguistic errors); TGCT trans rs3780486 0.541 rs10738909 chr9:33148834 T/C cg20290983 chr6:43655470 MRPS18A 0.78 8.36 0.6 1.08e-13 IgG glycosylation; TGCT cis rs4713118 0.955 rs9468206 chr6:27690453 G/T cg10876282 chr6:28092338 ZSCAN16 0.5 4.67 0.39 7.86e-6 Parkinson's disease; TGCT cis rs3741404 0.895 rs1860368 chr11:63994692 T/C cg19570321 chr11:63258214 HRASLS5 -0.46 -5.28 -0.43 5.67e-7 Platelet count; TGCT cis rs7412746 0.553 rs59337856 chr1:150746406 G/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs875971 0.929 rs10950041 chr7:65973875 T/C cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.1e-6 Aortic root size; TGCT cis rs12497850 0.864 rs4955410 chr3:49181218 A/G cg07636037 chr3:49044803 WDR6 0.94 10.1 0.67 7.08e-18 Parkinson's disease; TGCT cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs854765 0.654 rs9911281 chr17:17762457 G/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.8 -0.4 4.56e-6 Total body bone mineral density; TGCT cis rs1799949 0.602 rs8176257 chr17:41216205 G/T cg23758822 chr17:41437982 NA 0.6 4.85 0.4 3.63e-6 Menopause (age at onset); TGCT cis rs13202913 0.652 rs9371528 chr6:151832668 G/A cg03627880 chr6:151815985 C6orf97 -0.55 -5.35 -0.43 4.1e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs4689388 0.853 rs6446479 chr4:6291737 G/C cg14416269 chr4:6271139 WFS1 0.4 5.29 0.43 5.44e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2742417 1.000 rs1534876 chr3:45741257 G/T cg04837898 chr3:45731254 SACM1L -0.52 -5.24 -0.43 6.71e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs10504229 0.683 rs16921937 chr8:58145010 A/G cg08280861 chr8:58055591 NA 0.4 4.76 0.39 5.34e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115154776 chr4:119774803 A/G cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg00024416 chr22:24240387 NA -0.26 -4.99 -0.41 2e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6490294 0.799 rs2339941 chr12:112490764 G/T cg10833066 chr12:111807467 FAM109A 0.37 5.44 0.44 2.68e-7 Mean platelet volume; TGCT cis rs68170813 0.523 rs111590023 chr7:107055323 T/C cg02696742 chr7:106810147 HBP1 -0.71 -5.9 -0.47 3.17e-8 Coronary artery disease; TGCT cis rs896854 0.684 rs2340534 chr8:95992330 G/A cg13393036 chr8:95962371 TP53INP1 -0.58 -7.95 -0.58 1e-12 Type 2 diabetes; TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg16325326 chr1:53192061 ZYG11B 0.6 6.91 0.53 2.3e-10 Monocyte count; TGCT cis rs1372520 0.684 rs2619355 chr4:90748374 A/C cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT cis rs7772486 0.782 rs7747576 chr6:146277827 C/T cg23711669 chr6:146136114 FBXO30 -0.87 -9.69 -0.66 6.98e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs56104184 0.723 rs73063524 chr19:49409004 T/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs911555 0.547 rs8006994 chr14:103841296 C/T cg12935359 chr14:103987150 CKB -0.32 -4.56 -0.38 1.21e-5 Intelligence (multi-trait analysis); TGCT cis rs7769051 0.522 rs7775241 chr6:133109022 T/C cg07930552 chr6:133119739 C6orf192 1.28 5.03 0.41 1.69e-6 Type 2 diabetes nephropathy; TGCT cis rs2836974 0.644 rs2836981 chr21:40688365 C/T cg11890956 chr21:40555474 PSMG1 -0.8 -7.22 -0.54 4.51e-11 Cognitive function; TGCT cis rs3749237 0.595 rs1464566 chr3:49459376 T/C cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs1008375 0.966 rs4698638 chr4:17632988 G/C cg10189774 chr4:17578691 LAP3 0.62 5.5 0.44 2.08e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7095607 0.606 rs6480311 chr10:69956848 T/C cg18986048 chr10:69913749 MYPN 0.56 5.87 0.47 3.76e-8 Lung function (FVC); TGCT cis rs10514758 0.744 rs72947752 chr3:114932571 C/T cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs10501293 0.667 rs4565888 chr11:42986051 G/A cg03447554 chr11:43094025 NA 0.44 6.43 0.5 2.5e-9 Cognitive performance; TGCT cis rs9858542 0.537 rs115753735 chr3:49355005 T/C cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.68 0.39 7.43e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs11190604 0.767 rs10883491 chr10:102196071 G/T cg16005271 chr10:102321736 NA 0.46 4.68 0.39 7.39e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9291683 0.566 rs13122689 chr4:10044648 A/G cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Bone mineral density; TGCT cis rs59197085 0.636 rs17165226 chr7:128453626 C/G cg00260937 chr7:128520193 KCP -0.43 -4.92 -0.4 2.68e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs614226 1.000 rs1614223 chr12:120964043 T/C cg10072921 chr12:121022843 NA -0.44 -4.74 -0.39 5.78e-6 Type 1 diabetes nephropathy; TGCT cis rs6500602 0.648 rs7702 chr16:4560929 G/C cg08645402 chr16:4508243 NA 0.19 4.83 0.4 4e-6 Schizophrenia; TGCT cis rs7223966 1.000 rs11870797 chr17:61804622 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7666738 0.753 rs13137152 chr4:98938044 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs10908448 chr1:154882544 A/G cg16680214 chr1:154839983 KCNN3 0.36 7.19 0.54 5.36e-11 Prostate cancer; TGCT cis rs1023500 0.551 rs133355 chr22:42440285 G/A cg15557168 chr22:42548783 NA -0.21 -5.28 -0.43 5.69e-7 Schizophrenia; TGCT cis rs9303542 0.625 rs11868098 chr17:46570869 C/G cg25032089 chr17:46643351 HOXB3 -0.52 -5.62 -0.45 1.22e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT trans rs335810 1.000 rs1704083 chr15:60504055 C/T cg22845496 chr15:54303927 UNC13C 1.01 7.3 0.55 3.06e-11 Type 2 diabetes; TGCT cis rs910316 0.967 rs4903292 chr14:75656245 A/G cg11812906 chr14:75593930 NEK9 0.71 7.05 0.53 1.13e-10 Height; TGCT cis rs10782582 0.586 rs12130324 chr1:76370012 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.54 4.6 0.38 1.02e-5 Daytime sleep phenotypes; TGCT cis rs72627509 0.951 rs72627508 chr4:57831564 C/G cg26694713 chr4:57773883 REST 0.75 6.72 0.52 5.99e-10 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg06873352 chr17:61820015 STRADA 0.56 6.15 0.48 9.93e-9 Prudent dietary pattern; TGCT cis rs6879260 1.000 rs729568 chr5:179732350 C/T cg02891314 chr5:179741120 GFPT2 0.41 7.12 0.54 7.57e-11 Height; TGCT cis rs7119038 0.818 rs76704408 chr11:118683327 G/T cg19308663 chr11:118741387 NA 0.27 5.56 0.45 1.61e-7 Sjögren's syndrome; TGCT cis rs752590 0.943 rs13407583 chr2:113967740 G/A cg27425262 chr2:113953981 PSD4;LOC440839 0.41 4.62 0.38 9.37e-6 Mucinous ovarian carcinoma; TGCT cis rs35000415 0.688 rs12537284 chr7:128717906 G/A cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs17253792 0.822 rs112739186 chr14:56065167 A/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs151997 0.962 rs39955 chr5:50187501 C/A cg06027927 chr5:50259733 NA 0.46 4.78 0.39 4.84e-6 Callous-unemotional behaviour; TGCT cis rs4862750 0.874 rs6553027 chr4:187875777 T/C cg03452623 chr4:187889614 NA -0.36 -5.46 -0.44 2.45e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.87e-10 Electroencephalogram traits; TGCT cis rs7447593 0.626 rs3812036 chr5:176813404 C/T cg06060754 chr5:176797920 RGS14 0.51 7.51 0.56 9.94e-12 Urinary electrolytes (magnesium/calcium ratio); TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg00024416 chr22:24240387 NA -0.25 -4.68 -0.39 7.42e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs853679 0.517 rs9468286 chr6:28079428 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs12477438 0.765 rs7591794 chr2:99567514 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.66 -5.64 -0.45 1.08e-7 Chronic sinus infection; TGCT cis rs9517302 0.847 rs9517300 chr13:99095057 T/C cg22223119 chr13:99095684 FARP1 -0.7 -9.17 -0.64 1.25e-15 Obesity-related traits; TGCT cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg17054783 chr10:134559939 INPP5A -0.22 -4.8 -0.4 4.46e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs8042680 0.554 rs8035844 chr15:91519642 C/T cg22570213 chr15:91497863 RCCD1 0.43 4.54 0.38 1.33e-5 Type 2 diabetes; TGCT cis rs739496 0.579 rs7974772 chr12:112332283 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9611565 0.504 rs5758452 chr22:42144927 G/A cg17554472 chr22:41940697 POLR3H 0.43 4.61 0.38 9.67e-6 Vitiligo; TGCT cis rs9296404 1 rs9296404 chr6:42925803 T/C cg27588902 chr6:42928151 GNMT -0.56 -6.8 -0.52 4.02e-10 Plasma homocysteine levels (post-methionine load test); TGCT cis rs10411936 0.962 rs10404046 chr19:16477255 G/C cg19006008 chr19:16999768 F2RL3 0.27 4.75 0.39 5.53e-6 White blood cell count;Multiple sclerosis; TGCT cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs28852677 chr4:99039509 T/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 1.000 rs72882102 chr6:66983408 C/A cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs1476679 1.000 rs34919929 chr7:100012334 G/A cg13334819 chr7:99746414 C7orf59 0.72 6.03 0.48 1.71e-8 Alzheimer's disease (late onset); TGCT trans rs797680 0.856 rs7526112 chr1:93747683 T/G cg27528825 chr2:159282178 CCDC148 0.34 6.72 0.52 5.93e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs12533831 0.556 rs2253592 chr7:150878260 C/G cg04712895 chr7:150801789 AGAP3 0.19 4.67 0.39 7.7e-6 Childhood ear infection; TGCT cis rs9549367 0.826 rs2302755 chr13:113898418 C/T cg18105134 chr13:113819100 PROZ -0.35 -5.85 -0.47 4.05e-8 Platelet distribution width; TGCT cis rs7666738 1.000 rs13144055 chr4:99026849 A/G cg05340658 chr4:99064831 C4orf37 0.46 4.57 0.38 1.18e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs11719291 0.831 rs11715177 chr3:48763894 G/A cg03547606 chr3:48723644 NCKIPSD 0.46 4.56 0.38 1.21e-5 Cognitive function; TGCT cis rs12549902 0.871 rs4736819 chr8:41509915 C/T cg21772509 chr8:41503840 NKX6-3 0.8 8.71 0.62 1.63e-14 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs2243480 0.901 rs35256305 chr7:65306405 T/C cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs4689388 0.647 rs9997824 chr4:6283253 T/C cg25554036 chr4:6271136 WFS1 0.53 6.84 0.52 3.19e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs644799 1.000 rs566204 chr11:95580926 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 9.73 0.66 5.62e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs34734847 0.787 rs695948 chr12:121149596 A/G cg21892295 chr12:121157589 UNC119B -0.21 -4.94 -0.41 2.47e-6 Mean corpuscular volume; TGCT cis rs751728 1.000 rs3806108 chr6:33767579 C/G cg13859433 chr6:33739653 LEMD2 -0.4 -7.46 -0.56 1.33e-11 Crohn's disease; TGCT cis rs58365266 1.000 rs58365266 chr3:195813757 C/T cg01181863 chr3:195395398 SDHAP2 -0.46 -4.87 -0.4 3.3e-6 Red cell distribution width; TGCT cis rs2243480 0.901 rs57126451 chr7:65416306 T/C cg18252515 chr7:66147081 NA -1.18 -7.51 -0.56 9.96e-12 Diabetic kidney disease; TGCT cis rs644799 0.965 rs11021313 chr11:95506907 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.82 0.7 1.31e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2455799 0.559 rs4685268 chr3:15923510 C/A cg12172478 chr3:16357591 RFTN1 -0.34 -5.14 -0.42 1.02e-6 Mean platelet volume; TGCT cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg22105103 chr4:187893119 NA 0.34 4.62 0.38 9.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg08645402 chr16:4508243 NA 0.2 4.82 0.4 4.04e-6 Schizophrenia; TGCT cis rs2115630 0.967 rs8028490 chr15:85277888 G/A cg17173187 chr15:85201210 NMB -0.39 -4.85 -0.4 3.67e-6 P wave terminal force; TGCT cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg24531977 chr5:56204891 C5orf35 -0.93 -8.14 -0.59 3.61e-13 Initial pursuit acceleration; TGCT cis rs7829975 0.533 rs1039917 chr8:8718850 C/T cg06636001 chr8:8085503 FLJ10661 0.75 6.9 0.53 2.31e-10 Mood instability; TGCT cis rs9393692 0.905 rs6916289 chr6:26289122 A/T cg00631329 chr6:26305371 NA -0.41 -6.09 -0.48 1.34e-8 Educational attainment; TGCT cis rs4665809 1.000 rs6704930 chr2:26325705 G/A cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs72615157 0.634 rs7789890 chr7:99800559 G/T cg00814883 chr7:100076585 TSC22D4 -0.52 -5.14 -0.42 1.06e-6 Lung function (FEV1/FVC); TGCT cis rs6988636 1.000 rs60827294 chr8:124187842 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs3782455 0.793 rs2290798 chr12:114404143 C/T cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs4665809 0.590 rs4665321 chr2:26433801 A/C cg22920501 chr2:26401640 FAM59B -0.8 -6.34 -0.5 3.8e-9 Gut microbiome composition (summer); TGCT cis rs7959452 0.640 rs1598543 chr12:69688757 G/T cg14784868 chr12:69753453 YEATS4 0.68 6.95 0.53 1.81e-10 Blood protein levels; TGCT cis rs4819052 0.959 rs9976074 chr21:46655638 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.81 6.65 0.51 8.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.906 rs28447218 chr8:58170813 T/G cg24829409 chr8:58192753 C8orf71 -0.51 -4.99 -0.41 2.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs9653442 0.564 rs6707067 chr2:100767232 G/A cg07810366 chr2:100720526 AFF3 -0.35 -5.26 -0.43 6e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6429082 0.523 rs704718 chr1:235666159 A/T cg26050004 chr1:235667680 B3GALNT2 0.82 9.15 0.63 1.46e-15 Adiposity; TGCT cis rs2721195 0.874 rs2721197 chr8:145727705 A/G cg17328964 chr8:145687451 CYHR1 -0.39 -5.32 -0.43 4.78e-7 Age at first birth; TGCT cis rs2153535 0.580 rs2143354 chr6:8517907 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs4478858 0.775 rs6701861 chr1:31708125 A/C cg00250761 chr1:31883323 NA -0.3 -5.71 -0.46 7.91e-8 Alcohol dependence; TGCT cis rs2243480 1.000 rs34933526 chr7:65383199 A/G cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs9926296 0.744 rs6860 chr16:89711120 C/T cg26513180 chr16:89883248 FANCA -0.66 -6.08 -0.48 1.38e-8 Vitiligo; TGCT cis rs10504229 0.775 rs17804840 chr8:58157045 C/T cg11062466 chr8:58055876 NA 0.37 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs425277 0.606 rs262663 chr1:2084598 T/C cg12140144 chr1:2984275 FLJ42875;PRDM16 -0.32 -4.46 -0.37 1.81e-5 Height; TGCT cis rs7659604 0.676 rs7691955 chr4:122700462 A/T cg06713675 chr4:122721982 EXOSC9 -0.62 -8.5 -0.61 5.12e-14 Type 2 diabetes; TGCT cis rs4240897 0.935 rs2236055 chr1:12042261 A/G cg13216073 chr1:12042593 MFN2 0.19 5.83 0.46 4.45e-8 Tuberculosis; TGCT cis rs2549003 0.811 rs10035166 chr5:131823927 C/T cg00255919 chr5:131827918 IRF1 -0.19 -4.52 -0.38 1.44e-5 Asthma (sex interaction); TGCT cis rs1799949 1.000 rs1545764 chr17:41424565 G/A cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs7666738 0.753 rs10033138 chr4:98981922 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs28374715 0.532 rs7164211 chr15:41705041 A/T cg18705301 chr15:41695430 NDUFAF1 -0.93 -17.29 -0.84 7.63e-35 Ulcerative colitis; TGCT cis rs1801251 1.000 rs2592102 chr2:233726772 G/T cg25237894 chr2:233734115 C2orf82 -0.33 -5.97 -0.47 2.34e-8 Coronary artery disease; TGCT cis rs317689 0.600 rs478188 chr12:69639215 A/G cg11871910 chr12:69753446 YEATS4 0.54 4.47 0.37 1.72e-5 Response to diuretic therapy; TGCT cis rs950776 0.545 rs28444683 chr15:78984507 C/A cg03762349 chr15:79060523 ADAMTS7 0.29 6.3 0.49 4.7e-9 Sudden cardiac arrest; TGCT cis rs2762353 0.574 rs4419666 chr6:25693274 C/T cg12310025 chr6:25882481 NA 0.91 8.98 0.63 3.56e-15 Blood metabolite levels; TGCT cis rs2639990 1.000 rs2639990 chr18:72915551 T/C cg03972071 chr18:72917163 ZADH2 0.83 5.63 0.45 1.14e-7 Vascular endothelial growth factor levels; TGCT cis rs9911578 1.000 rs7223955 chr17:56917053 C/A cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2721195 0.549 rs2620666 chr8:145703413 T/C cg11211951 chr8:145729740 GPT 0.23 5.55 0.45 1.62e-7 Age at first birth; TGCT cis rs10465746 0.935 rs11163878 chr1:84442654 G/A cg10977910 chr1:84465055 TTLL7 0.63 6.23 0.49 6.49e-9 Obesity-related traits; TGCT cis rs2816062 0.710 rs2816052 chr1:18895536 T/C cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT cis rs12615966 0.932 rs58391435 chr2:105368520 A/G cg16465502 chr2:105461796 NA 0.75 4.65 0.39 8.22e-6 Pancreatic cancer; TGCT cis rs35306767 0.953 rs10904583 chr10:983498 T/C cg20503657 chr10:835505 NA 0.58 8.09 0.59 4.54e-13 Eosinophil percentage of granulocytes; TGCT cis rs611744 0.810 rs672161 chr8:109164182 G/A cg21045802 chr8:109455806 TTC35 0.69 6.06 0.48 1.51e-8 Dupuytren's disease; TGCT cis rs2243480 1.000 rs6460261 chr7:65215580 T/C cg20637647 chr7:64974828 NA -0.9 -5.06 -0.41 1.45e-6 Diabetic kidney disease; TGCT cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9517320 0.515 rs61969456 chr13:99174799 C/G cg07423050 chr13:99094983 FARP1 -0.28 -5.64 -0.45 1.11e-7 Longevity; TGCT cis rs5769765 1.000 rs768619 chr22:50287266 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs9926296 0.607 rs11076629 chr16:89875259 T/C cg27121462 chr16:89883253 FANCA 0.58 5.23 0.43 6.88e-7 Vitiligo; TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg08859206 chr1:53392774 SCP2 -0.43 -6.71 -0.52 6.09e-10 Monocyte count; TGCT cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg17747265 chr1:1875780 NA 0.39 7.34 0.55 2.52e-11 Body mass index; TGCT cis rs6459680 0.504 rs1881008 chr7:156259409 T/A cg02321112 chr7:156810523 NA 0.35 4.47 0.37 1.74e-5 Glomerular filtration rate (creatinine); TGCT cis rs2204008 0.837 rs11183232 chr12:37941053 A/G cg26384229 chr12:38710491 ALG10B 0.85 7.82 0.57 1.94e-12 Bladder cancer; TGCT cis rs526231 0.819 rs35801 chr5:102608213 G/T cg05225461 chr5:102596755 C5orf30 0.23 4.65 0.39 8.39e-6 Primary biliary cholangitis; TGCT cis rs67072384 1.000 rs72966113 chr11:72450970 C/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs4799461 0.773 rs9953231 chr18:35150526 G/A cg27332583 chr18:35150602 NA 0.29 4.46 0.37 1.83e-5 Neuroticism; TGCT cis rs7582180 0.700 rs2309852 chr2:100982527 T/C cg08017756 chr2:100939284 LONRF2 -0.31 -4.95 -0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs4891159 0.790 rs689885 chr18:74110563 T/G cg24786174 chr18:74118243 ZNF516 0.62 9.53 0.65 1.73e-16 Longevity; TGCT cis rs6688613 1.000 rs7550698 chr1:166951081 A/G cg07049167 chr1:166818506 POGK 0.21 4.5 0.37 1.57e-5 Refractive astigmatism; TGCT cis rs1372520 0.684 rs2737010 chr4:90746466 G/A cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.09e-7 Neuroticism; TGCT cis rs3087591 0.960 rs2952984 chr17:29469614 T/C cg24425628 chr17:29625626 OMG;NF1 0.51 7.9 0.58 1.25e-12 Hip circumference; TGCT trans rs3780486 0.505 rs10117038 chr9:33122626 T/C cg04842962 chr6:43655489 MRPS18A 0.82 8.89 0.62 5.88e-15 IgG glycosylation; TGCT cis rs59698941 0.550 rs11748063 chr5:132200943 C/T cg27099455 chr5:132201840 GDF9;UQCRQ 0.3 5.02 0.41 1.75e-6 Apolipoprotein A-IV levels; TGCT cis rs10782582 0.609 rs5745430 chr1:76332994 C/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs3796352 0.667 rs11720228 chr3:52877270 G/A cg27565382 chr3:53032988 SFMBT1 0.49 4.47 0.37 1.75e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg15242686 chr22:24348715 GSTTP1 0.44 6.02 0.48 1.86e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1865760 0.827 rs9295681 chr6:25944117 T/G cg17042849 chr6:26104293 HIST1H4C -0.5 -4.55 -0.38 1.27e-5 Height; TGCT cis rs6138458 0.585 rs1007881 chr20:25014385 A/G cg26195577 chr20:24973756 C20orf3 1.01 9.23 0.64 9.14e-16 Blood protein levels; TGCT cis rs12541335 0.590 rs11136002 chr8:22217082 C/T cg18135555 chr8:22132992 PIWIL2 0.29 5.61 0.45 1.23e-7 Hypertriglyceridemia; TGCT cis rs1570884 0.536 rs1359541 chr13:50158939 A/G cg08779649 chr13:50194554 NA 0.38 6.25 0.49 5.89e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT trans rs7726839 0.540 rs72703080 chr5:595238 A/G cg11887960 chr12:57824829 NA 1.2 9.65 0.65 8.99e-17 Obesity-related traits; TGCT cis rs9296092 0.538 rs35381461 chr6:33519751 T/C cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2439831 0.681 rs526450 chr15:43599325 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.12 9.1 0.63 1.91e-15 Lung cancer in ever smokers; TGCT cis rs11122272 0.735 rs2244994 chr1:231537127 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.5 -0.5 1.77e-9 Hemoglobin concentration; TGCT cis rs2242116 0.592 rs6442039 chr3:46960797 C/G cg27129171 chr3:47204927 SETD2 0.57 5.0 0.41 1.91e-6 Birth weight; TGCT cis rs752092 0.855 rs7171515 chr15:101769618 C/T cg25114630 chr15:101792522 CHSY1 0.5 4.7 0.39 6.7e-6 Corneal structure; TGCT cis rs7917772 0.507 rs2778036 chr10:104485725 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.65 5.45 0.44 2.61e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg02675527 chr2:114030824 PAX8;LOC440839 -0.52 -6.89 -0.53 2.52e-10 Lymphocyte counts; TGCT cis rs6964587 0.869 rs10241720 chr7:91527367 G/T cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs9549260 0.755 rs2297627 chr13:41233931 A/G cg21288729 chr13:41239152 FOXO1 0.96 9.98 0.67 1.45e-17 Red blood cell count; TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.91 -0.4 2.81e-6 Prudent dietary pattern; TGCT trans rs916888 0.647 rs199524 chr17:44848438 G/T cg22433210 chr17:43662623 NA -0.92 -7.55 -0.56 8e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11971779 0.625 rs10260850 chr7:139003602 G/T cg07862535 chr7:139043722 LUC7L2 0.59 4.66 0.39 7.89e-6 Diisocyanate-induced asthma; TGCT cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg21280719 chr6:42927975 GNMT -0.37 -4.52 -0.38 1.41e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2404602 0.647 rs907593 chr15:77196953 G/A cg22467129 chr15:76604101 ETFA 0.55 5.52 0.44 1.9e-7 Blood metabolite levels; TGCT cis rs13191362 1.000 rs34714518 chr6:163080778 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.83 0.52 3.35e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs782590 0.967 rs782586 chr2:55836165 A/C cg03859395 chr2:55845619 SMEK2 0.92 11.37 0.71 5.88e-21 Metabolic syndrome; TGCT cis rs2288884 0.943 rs11084132 chr19:52514580 C/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.47 -0.37 1.77e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs4886920 0.518 rs4624137 chr15:78078903 A/G cg25212270 chr15:78015279 NA -0.28 -5.12 -0.42 1.16e-6 Neuroticism; TGCT cis rs2549003 0.966 rs10065633 chr5:131816716 T/C cg00255919 chr5:131827918 IRF1 0.22 5.15 0.42 1.01e-6 Asthma (sex interaction); TGCT cis rs875971 1.000 rs709597 chr7:65825983 A/G cg00343986 chr7:65444356 GUSB -0.2 -4.47 -0.37 1.75e-5 Aortic root size; TGCT cis rs26868 0.816 rs26871 chr16:2248133 G/A cg26873644 chr16:2260806 C16orf79 -0.24 -4.8 -0.4 4.51e-6 Height; TGCT cis rs896854 0.846 rs13254283 chr8:95914103 G/T cg13393036 chr8:95962371 TP53INP1 -0.59 -8.0 -0.58 7.34e-13 Type 2 diabetes; TGCT cis rs1670533 1.000 rs604597 chr4:1094151 G/A cg27284194 chr4:1044797 NA -0.7 -6.06 -0.48 1.53e-8 Recombination rate (females); TGCT cis rs7927771 0.832 rs67116452 chr11:47385194 G/A cg21462715 chr11:47870315 NUP160 0.57 4.63 0.38 9.08e-6 Subjective well-being; TGCT trans rs1814175 0.817 rs10769598 chr11:49669326 C/G cg03929089 chr4:120376271 NA -0.71 -8.34 -0.6 1.21e-13 Height; TGCT cis rs477895 1.000 rs2276014 chr11:64081445 G/A cg04317338 chr11:64019027 PLCB3 0.71 5.65 0.45 1.05e-7 Mean platelet volume; TGCT cis rs72781680 0.716 rs2712056 chr2:23959131 C/T cg08917208 chr2:24149416 ATAD2B 0.78 5.26 0.43 6.01e-7 Lymphocyte counts; TGCT cis rs76878669 0.561 rs12794121 chr11:66126169 G/T cg18002602 chr11:66138449 SLC29A2 0.54 6.62 0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs9467711 0.790 rs72843784 chr6:26498758 G/T cg16898833 chr6:26189333 HIST1H4D 1.35 5.89 0.47 3.43e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs7953508 0.506 rs1316740 chr12:93968288 C/A cg18151635 chr12:93972918 NA -0.19 -4.52 -0.38 1.41e-5 Pubertal anthropometrics; TGCT cis rs6964587 0.967 rs17164315 chr7:91659150 C/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg06896619 chr17:61851486 DDX42;CCDC47 0.51 4.96 0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs7312933 0.703 rs7957471 chr12:42545591 G/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1008375 0.574 rs7670135 chr4:17566221 G/T cg10189774 chr4:17578691 LAP3 0.62 5.65 0.45 1.05e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs514406 0.661 rs550561 chr1:53375134 C/T cg08859206 chr1:53392774 SCP2 -0.46 -7.42 -0.55 1.64e-11 Monocyte count; TGCT cis rs11614913 0.509 rs12300425 chr12:54395082 G/T cg16264616 chr12:54390824 NA 0.34 4.84 0.4 3.76e-6 Waist circumference adjusted for body mass index; TGCT cis rs1862618 0.671 rs2591964 chr5:56236900 T/G cg20203395 chr5:56204925 C5orf35 0.53 4.92 0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg23708337 chr7:1209742 NA 0.55 5.45 0.44 2.62e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7772486 0.875 rs2814877 chr6:146299763 C/G cg05347473 chr6:146136440 FBXO30 0.53 5.0 0.41 1.87e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs13115356 chr4:98933171 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs174479 0.647 rs174454 chr11:61650747 A/G cg19610905 chr11:61596333 FADS2 -0.61 -5.22 -0.42 7.32e-7 Sphingolipid levels; TGCT cis rs804280 0.662 rs11784764 chr8:11610874 C/T cg26752888 chr8:11627280 NEIL2 0.7 5.47 0.44 2.42e-7 Myopia (pathological); TGCT cis rs2721195 0.614 rs12719778 chr8:145879883 T/C cg15320075 chr8:145703422 NA 0.64 5.84 0.46 4.31e-8 Age at first birth; TGCT cis rs10501293 1.000 rs2114087 chr11:43133002 G/C cg03447554 chr11:43094025 NA -0.48 -6.72 -0.52 5.89e-10 Cognitive performance; TGCT cis rs7192750 0.562 rs4788566 chr16:71893470 T/C cg06353428 chr16:71660113 MARVELD3 0.8 7.26 0.55 3.8e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs10089 1.000 rs10061367 chr5:127449021 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg14893161 chr1:205819251 PM20D1 0.57 8.17 0.59 2.97e-13 Menarche (age at onset); TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs155076 0.711 rs9550724 chr13:21885030 G/T cg11317459 chr13:21872234 NA 1.32 13.31 0.77 1.2e-25 White matter hyperintensity burden; TGCT cis rs9733 0.596 rs6686525 chr1:150635811 C/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs1218582 0.596 rs11264275 chr1:154825270 G/T cg06418219 chr1:154948305 SHC1;CKS1B 0.5 4.73 0.39 5.92e-6 Prostate cancer; TGCT cis rs67478160 0.619 rs12885018 chr14:104273812 A/G cg26031613 chr14:104095156 KLC1 -0.64 -6.57 -0.51 1.23e-9 Schizophrenia; TGCT cis rs1113500 0.787 rs4571989 chr1:108631344 G/A cg22161131 chr1:109420278 GPSM2 0.49 4.54 0.38 1.34e-5 Growth-regulated protein alpha levels; TGCT cis rs453301 0.624 rs2288673 chr8:8860276 G/T cg06636001 chr8:8085503 FLJ10661 0.8 7.14 0.54 7.09e-11 Joint mobility (Beighton score); TGCT cis rs56104184 0.830 rs55966626 chr19:49342396 G/T cg21252483 chr19:49399788 TULP2 -0.42 -5.58 -0.45 1.46e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4478858 0.684 rs10798838 chr1:31719450 G/A cg07478791 chr1:31886160 SERINC2 -0.49 -4.8 -0.4 4.51e-6 Alcohol dependence; TGCT cis rs4478037 1.000 rs58864038 chr3:33161355 G/A cg19404215 chr3:33155277 CRTAP 1.28 8.55 0.61 3.75e-14 Major depressive disorder; TGCT cis rs7599312 0.586 rs4404217 chr2:213385817 G/A cg16329650 chr2:213403929 ERBB4 0.55 4.62 0.38 9.45e-6 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7178572 0.568 rs1191196 chr15:77646504 C/T cg15453836 chr15:77711506 NA 0.42 4.79 0.4 4.68e-6 Type 2 diabetes; TGCT cis rs2239547 0.657 rs12488303 chr3:52862003 G/A cg11645453 chr3:52864694 ITIH4 0.34 5.67 0.45 9.34e-8 Schizophrenia; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg16325326 chr1:53192061 ZYG11B 0.61 6.79 0.52 4.18e-10 Monocyte count; TGCT cis rs1552244 0.872 rs6792951 chr3:10119603 C/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT trans rs10504390 0.656 rs76479008 chr8:66486620 G/T cg18118147 chr19:51128640 SYT3 -0.77 -6.81 -0.52 3.71e-10 IgG glycosylation; TGCT cis rs644799 1.000 rs500054 chr11:95593806 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.04 0.59 6.21e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg13683864 chr3:40499215 RPL14 1.14 12.22 0.74 4.89e-23 Renal cell carcinoma; TGCT cis rs6815814 0.950 rs73236617 chr4:38793860 C/G cg02016764 chr4:38805732 TLR1 -0.34 -5.4 -0.44 3.2e-7 Breast cancer; TGCT cis rs57590327 0.503 rs13075250 chr3:81907952 T/C cg07356753 chr3:81810745 GBE1 -0.67 -6.16 -0.48 9.35e-9 Extraversion; TGCT cis rs2075165 0.901 rs1043165 chr1:156220056 T/C cg16558208 chr1:156270281 VHLL 0.26 4.5 0.37 1.52e-5 Tonsillectomy; TGCT cis rs1163251 0.902 rs627707 chr1:120217133 C/G cg19096424 chr1:120255104 PHGDH 0.56 5.29 0.43 5.46e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs10011009 chr4:98981749 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs861020 0.630 rs627069 chr1:210004613 C/G cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg18252515 chr7:66147081 NA -1.09 -6.4 -0.5 2.88e-9 Diabetic kidney disease; TGCT cis rs7772486 0.625 rs9390355 chr6:146112942 C/T cg23711669 chr6:146136114 FBXO30 -0.86 -9.74 -0.66 5.4e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7312933 0.701 rs10880260 chr12:42561398 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 4.99 0.41 1.99e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg06238570 chr21:40685208 BRWD1 0.69 6.43 0.5 2.55e-9 Cognitive function; TGCT cis rs9549260 0.755 rs7993233 chr13:41219434 T/A cg21288729 chr13:41239152 FOXO1 1.01 10.71 0.69 2.36e-19 Red blood cell count; TGCT cis rs210138 0.882 rs407710 chr6:33554257 A/G cg07679836 chr6:33548423 BAK1 0.35 4.63 0.38 9.12e-6 Testicular germ cell tumor; TGCT cis rs9303401 0.659 rs12150536 chr17:56640834 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.88 0.47 3.62e-8 Cognitive test performance; TGCT cis rs950169 0.920 rs17300048 chr15:84749477 C/T cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.14e-8 Schizophrenia; TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg06601766 chr17:61851465 DDX42;CCDC47 -0.5 -4.61 -0.38 9.7e-6 Prudent dietary pattern; TGCT cis rs2099527 0.504 rs1548256 chr10:52268572 A/T cg12753529 chr10:51525504 NA 0.23 4.54 0.38 1.32e-5 Life satisfaction; TGCT cis rs9430161 0.644 rs34365965 chr1:11034442 G/A cg02454025 chr1:11042201 C1orf127 0.94 11.41 0.72 4.75e-21 Ewing sarcoma; TGCT cis rs4478858 0.735 rs10798842 chr1:31778648 A/G cg07478791 chr1:31886160 SERINC2 -0.48 -4.61 -0.38 1e-5 Alcohol dependence; TGCT cis rs68170813 0.559 rs7804979 chr7:106999453 C/G cg02696742 chr7:106810147 HBP1 -0.73 -5.95 -0.47 2.6e-8 Coronary artery disease; TGCT cis rs10927875 0.632 rs4481843 chr1:16128205 G/A cg21385522 chr1:16154831 NA -0.96 -15.62 -0.81 4.59e-31 Dilated cardiomyopathy; TGCT cis rs12220238 0.915 rs12217890 chr10:76024496 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 6.27 0.49 5.39e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs35146811 0.696 rs1727124 chr7:99804104 T/G cg13334819 chr7:99746414 C7orf59 0.74 6.32 0.49 4.34e-9 Coronary artery disease; TGCT cis rs6570726 0.791 rs436156 chr6:145874873 A/G cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11085466 1.000 rs73552468 chr19:21772097 G/A cg02997983 chr19:21646781 NA -0.6 -4.59 -0.38 1.06e-5 Colorectal or endometrial cancer; TGCT cis rs694419 0.579 rs9965948 chr18:60201864 T/G cg13506219 chr18:60193840 ZCCHC2 -0.53 -4.78 -0.39 4.82e-6 Serum albumin level; TGCT cis rs17221829 0.703 rs4237550 chr11:89360585 C/T cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs11792861 0.816 rs3763643 chr9:111695607 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 5.0 0.41 1.88e-6 Menarche (age at onset); TGCT cis rs929354 0.772 rs2051876 chr7:157009037 A/G cg05182265 chr7:156933206 UBE3C 0.39 8.77 0.62 1.16e-14 Body mass index; TGCT cis rs5769707 0.967 rs5770585 chr22:50007874 G/A cg10356904 chr22:49881777 NA -0.23 -4.69 -0.39 7.05e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1552244 0.832 rs115415687 chr3:10195704 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 1.1 6.25 0.49 6.06e-9 Alzheimer's disease; TGCT cis rs7714584 1.000 rs11740172 chr5:150300278 A/G cg22134413 chr5:150180641 NA 1.01 7.24 0.55 4.17e-11 Crohn's disease; TGCT trans rs9985766 1.000 rs28654919 chr4:151017407 C/T cg02993991 chr19:4064177 ZBTB7A 0.57 6.7 0.52 6.59e-10 Coronary artery disease;Myocardial infarction; TGCT cis rs7731657 0.537 rs7726927 chr5:130215211 G/T cg08523029 chr5:130500466 HINT1 -0.55 -4.83 -0.4 3.86e-6 Fasting plasma glucose; TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg16325326 chr1:53192061 ZYG11B 0.59 7.1 0.54 8.48e-11 Monocyte count; TGCT trans rs916888 0.610 rs199454 chr17:44800110 G/A cg22433210 chr17:43662623 NA -0.94 -7.97 -0.58 8.83e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2795502 1.000 rs1581702 chr10:43344246 G/A cg20628663 chr10:43360327 NA 0.45 6.42 0.5 2.61e-9 Blood protein levels; TGCT cis rs861020 1.000 rs7555285 chr1:209970355 C/G cg05527609 chr1:210001259 C1orf107 -0.92 -7.72 -0.57 3.42e-12 Orofacial clefts; TGCT cis rs10540 0.818 rs12806089 chr11:501468 G/A cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs1395 0.922 rs6547521 chr2:27488432 G/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.64 0.51 8.74e-10 Blood metabolite levels; TGCT cis rs453301 0.571 rs2929452 chr8:9084465 G/A cg06636001 chr8:8085503 FLJ10661 -0.56 -4.97 -0.41 2.14e-6 Joint mobility (Beighton score); TGCT cis rs2580764 0.565 rs35631428 chr2:55244438 G/A cg09592903 chr2:55203963 RTN4 -0.27 -6.09 -0.48 1.3e-8 Mean platelet volume; TGCT cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg17554472 chr22:41940697 POLR3H 0.47 5.04 0.41 1.63e-6 Vitiligo; TGCT cis rs28595532 0.841 rs115725150 chr4:119768647 T/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs13191362 1.000 rs2156257 chr6:163100710 G/T cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.96 0.67 1.56e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs478304 0.934 rs498354 chr11:65528213 A/G cg17480646 chr11:65405466 SIPA1 0.43 5.38 0.43 3.62e-7 Acne (severe); TGCT cis rs17221829 0.733 rs7945304 chr11:89372524 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs992157 0.798 rs2382819 chr2:219155909 G/T cg00012203 chr2:219082015 ARPC2 -0.77 -7.41 -0.55 1.68e-11 Colorectal cancer; TGCT cis rs6121246 0.697 rs7269866 chr20:30232504 G/A cg21427119 chr20:30132790 HM13 -0.37 -5.19 -0.42 8.51e-7 Mean corpuscular hemoglobin; TGCT cis rs523522 0.923 rs10774553 chr12:120954984 T/C cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs7914558 0.902 rs3736922 chr10:104850632 A/G cg04362960 chr10:104952993 NT5C2 -0.53 -4.61 -0.38 9.97e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2439831 1.000 rs2584725 chr15:43793135 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.19 0.59 2.67e-13 Lung cancer in ever smokers; TGCT cis rs60843830 0.928 rs62114494 chr2:211317 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.69 6.26 0.49 5.66e-9 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg22907277 chr7:1156413 C7orf50 0.2 4.48 0.37 1.7e-5 Longevity;Endometriosis; TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg02493798 chr17:6899577 ALOX12 0.43 4.65 0.39 8.35e-6 Tonsillectomy; TGCT cis rs7296418 0.961 rs1790106 chr12:123591596 G/T cg13010344 chr12:123464640 ARL6IP4 -0.32 -4.46 -0.37 1.81e-5 Platelet count; TGCT cis rs11783469 0.524 rs17089283 chr8:23335762 A/T cg00472375 chr8:23315376 ENTPD4 0.68 5.11 0.42 1.17e-6 Reticulocyte count; TGCT cis rs921968 0.643 rs659185 chr2:219335935 C/T cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT trans rs7618501 0.521 rs3774759 chr3:49939120 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.36 0.6 1.06e-13 Intelligence (multi-trait analysis); TGCT cis rs28595532 1.000 rs11098451 chr4:119717673 C/T cg14228332 chr4:119757509 SEC24D 0.91 5.64 0.45 1.08e-7 Cannabis dependence symptom count; TGCT cis rs736408 0.774 rs4687551 chr3:52823448 C/T cg10802521 chr3:52805072 NEK4 0.61 6.91 0.53 2.23e-10 Bipolar disorder; TGCT cis rs713587 0.935 rs4430895 chr2:25161386 C/T cg01884057 chr2:25150051 NA 0.39 7.9 0.58 1.29e-12 Body mass index in non-asthmatics; TGCT cis rs9517320 0.534 rs4772088 chr13:99138270 T/G cg20487152 chr13:99095054 FARP1 -0.25 -4.63 -0.38 8.94e-6 Longevity; TGCT cis rs10193935 1.000 rs4048 chr2:42424595 A/C cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2839186 1.000 rs2839186 chr21:47690068 C/T cg13732083 chr21:47605072 C21orf56 0.36 4.57 0.38 1.14e-5 Testicular germ cell tumor; TGCT cis rs6880778 0.505 rs10473183 chr5:40370251 T/C cg01087697 chr5:40835557 RPL37 0.53 4.83 0.4 3.95e-6 Inflammatory bowel disease; TGCT cis rs3087591 0.960 rs7212264 chr17:29454766 C/T cg24425628 chr17:29625626 OMG;NF1 0.49 7.28 0.55 3.29e-11 Hip circumference; TGCT cis rs6831352 0.879 rs4699717 chr4:100066137 C/T cg12011299 chr4:100065546 ADH4 -0.43 -5.07 -0.41 1.44e-6 Alcohol dependence; TGCT cis rs2204008 0.837 rs11495548 chr12:38076756 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.24 0.43 6.69e-7 Bladder cancer; TGCT cis rs2108225 0.967 rs7785790 chr7:107449896 C/T cg20438043 chr7:107601757 LAMB1 0.24 4.46 0.37 1.78e-5 Ulcerative colitis; TGCT cis rs877282 0.838 rs34778553 chr10:796865 T/C cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs5769765 0.817 rs8142561 chr22:50291750 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.86 -0.73 3.71e-22 Schizophrenia; TGCT cis rs1008375 1.000 rs10012335 chr4:17628630 C/G cg10189774 chr4:17578691 LAP3 0.59 5.13 0.42 1.06e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9479482 1.000 rs11155697 chr6:150357423 C/T cg03788504 chr6:150331562 NA -0.24 -4.63 -0.38 9.01e-6 Alopecia areata; TGCT cis rs17331151 0.573 rs2276818 chr3:52864635 A/G cg15956490 chr3:53032818 SFMBT1 0.46 5.75 0.46 6.57e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2692947 0.770 rs72823920 chr2:96430876 G/A cg23100626 chr2:96804247 ASTL 0.37 4.44 0.37 1.93e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4746818 1.000 rs906218 chr10:70960913 C/T cg11621586 chr10:70884670 VPS26A 1.21 9.94 0.67 1.73e-17 Left atrial antero-posterior diameter; TGCT trans rs10504390 0.527 rs4392943 chr8:66523799 C/A cg18118147 chr19:51128640 SYT3 -0.77 -6.85 -0.52 2.99e-10 IgG glycosylation; TGCT cis rs11585357 0.557 rs17378462 chr1:17595702 C/T cg08277548 chr1:17600880 PADI3 -0.72 -5.01 -0.41 1.84e-6 Hair shape; TGCT cis rs9911578 0.867 rs4793941 chr17:56472366 G/A cg05425664 chr17:57184151 TRIM37 0.61 5.86 0.47 4e-8 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.966 rs2261720 chr20:25260641 T/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9399135 0.935 rs949547 chr6:135343499 C/G cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT cis rs2371030 0.965 rs12998879 chr2:211583332 G/A cg18417063 chr2:211583084 NA -0.31 -4.45 -0.37 1.91e-5 Non-small cell lung cancer; TGCT cis rs2970818 0.831 rs2970810 chr12:4608103 A/G cg02722637 chr12:4922070 KCNA6 0.32 5.75 0.46 6.67e-8 Phosphorus levels; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs4689388 0.926 rs10937718 chr4:6295217 T/C cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2197308 0.765 rs68029712 chr12:37906585 T/G cg13010199 chr12:38710504 ALG10B 0.67 5.34 0.43 4.33e-7 Morning vs. evening chronotype; TGCT cis rs826415 0.864 rs41276588 chr1:118148384 G/A cg11819305 chr1:117910798 MAN1A2 0.5 4.47 0.37 1.78e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9549367 0.713 rs3024764 chr13:113824314 A/G cg18105134 chr13:113819100 PROZ -0.47 -8.58 -0.61 3.23e-14 Platelet distribution width; TGCT cis rs208515 0.525 rs12215007 chr6:66671008 C/T cg07460842 chr6:66804631 NA -0.86 -8.95 -0.63 4.31e-15 Exhaled nitric oxide levels; TGCT cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg03264133 chr6:25882463 NA -0.65 -5.88 -0.47 3.48e-8 Intelligence (multi-trait analysis); TGCT cis rs11992186 0.597 rs11781841 chr8:8595263 T/A cg15556689 chr8:8085844 FLJ10661 -0.56 -4.66 -0.39 8.09e-6 Neuroticism; TGCT cis rs79057730 0.599 rs4720893 chr7:804434 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.66 6.27 0.49 5.39e-9 Initial pursuit acceleration; TGCT cis rs3008870 0.959 rs1886686 chr1:67390468 C/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.09 0.74 1.01e-22 Lymphocyte percentage of white cells; TGCT trans rs77457752 0.525 rs10120716 chr9:13897909 G/A cg23609682 chr1:3070786 PRDM16 0.5 6.79 0.52 4.09e-10 Breast cancer; TGCT cis rs3820068 0.871 rs76155024 chr1:15807142 T/C cg05660106 chr1:15850417 CASP9 1.13 11.01 0.7 4.37e-20 Systolic blood pressure; TGCT cis rs12780845 0.505 rs10904893 chr10:17204944 T/C cg01003015 chr10:17271136 VIM -0.51 -4.47 -0.37 1.76e-5 Homocysteine levels; TGCT cis rs10540 1.000 rs10540 chr11:494662 G/A cg03352830 chr11:487213 PTDSS2 0.26 4.46 0.37 1.8e-5 Body mass index; TGCT cis rs3749237 0.595 rs4955412 chr3:49418168 A/C cg03060546 chr3:49711283 APEH 0.77 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg18876405 chr7:65276391 NA 0.37 5.85 0.47 4.02e-8 Aortic root size; TGCT cis rs2243480 1.000 rs402418 chr7:65509469 G/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs10949834 0.642 rs2356530 chr7:73533221 T/A cg07137043 chr7:73588983 EIF4H -0.74 -4.53 -0.38 1.38e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg20203395 chr5:56204925 C5orf35 -0.71 -5.58 -0.45 1.44e-7 Type 2 diabetes; TGCT cis rs3087591 1.000 rs2107360 chr17:29697901 C/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.28 -0.55 3.31e-11 Hip circumference; TGCT cis rs41271951 0.512 rs114222784 chr1:151084781 C/T cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs10504229 0.683 rs11785258 chr8:58132893 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs2677744 0.626 rs3743452 chr15:91497515 C/T cg22570213 chr15:91497863 RCCD1 -0.41 -5.04 -0.41 1.6e-6 Attention deficit hyperactivity disorder; TGCT cis rs9527 0.662 rs10883783 chr10:104591152 T/A cg15744005 chr10:104629667 AS3MT -0.48 -5.82 -0.46 4.72e-8 Arsenic metabolism; TGCT cis rs1799949 1.000 rs4793236 chr17:41436440 T/C cg23758822 chr17:41437982 NA 0.69 6.41 0.5 2.75e-9 Menopause (age at onset); TGCT cis rs873946 0.586 rs12770021 chr10:134562021 G/A cg27286337 chr10:134555280 INPP5A 0.37 4.54 0.38 1.3e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2013441 0.965 rs9896221 chr17:20180337 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs7829975 0.774 rs35039922 chr8:8675325 A/T cg15556689 chr8:8085844 FLJ10661 0.68 6.15 0.48 1e-8 Mood instability; TGCT cis rs11971779 0.680 rs66491565 chr7:139088977 C/G cg07862535 chr7:139043722 LUC7L2 0.71 5.55 0.45 1.63e-7 Diisocyanate-induced asthma; TGCT cis rs10276381 0.786 rs73300665 chr7:28227024 G/A cg23620719 chr7:28220237 JAZF1 0.95 5.75 0.46 6.52e-8 Crohn's disease; TGCT cis rs7119038 0.629 rs10892272 chr11:118602707 C/G cg19308663 chr11:118741387 NA 0.23 4.57 0.38 1.16e-5 Sjögren's syndrome; TGCT cis rs12580194 0.593 rs12099665 chr12:55731191 G/T cg10672482 chr12:55725839 OR6C3 -0.54 -4.77 -0.39 5.17e-6 Cancer; TGCT cis rs4253772 0.575 rs6008684 chr22:46719100 C/G cg24881330 chr22:46731750 TRMU 1.01 4.96 0.41 2.22e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg16497277 chr3:49208875 KLHDC8B -0.53 -5.13 -0.42 1.09e-6 Menarche (age at onset); TGCT cis rs483180 0.512 rs866321 chr1:120224469 T/C cg19096424 chr1:120255104 PHGDH 0.59 5.58 0.45 1.43e-7 Macular telangiectasia type 2; TGCT cis rs7267979 0.816 rs404775 chr20:25481117 A/G cg16686733 chr20:25566563 NINL 0.52 5.05 0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9435341 1.000 rs1762484 chr1:107613923 A/C cg09367891 chr1:107599246 PRMT6 -0.62 -5.17 -0.42 8.93e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs7213347 0.780 rs170041 chr17:2170216 C/T cg13315690 chr17:1944831 OVCA2;DPH1 0.38 4.69 0.39 7.1e-6 Total body bone mineral density; TGCT trans rs208520 0.690 rs4386800 chr6:66755242 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.98 10.83 0.7 1.19e-19 Exhaled nitric oxide output; TGCT cis rs2692947 0.666 rs10183151 chr2:96774786 T/G cg23100626 chr2:96804247 ASTL -0.39 -4.61 -0.38 1e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4253772 0.591 rs6519994 chr22:46656805 A/G cg09491104 chr22:46646882 C22orf40 0.63 6.39 0.5 3.05e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs4478037 1.000 rs61433006 chr3:33162363 T/A cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs4808199 0.895 rs4808196 chr19:19476520 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.7 4.94 0.41 2.48e-6 Nonalcoholic fatty liver disease; TGCT cis rs73001065 0.792 rs16996148 chr19:19658472 G/T cg03709012 chr19:19516395 GATAD2A 1.08 5.49 0.44 2.14e-7 LDL cholesterol; TGCT cis rs523522 1.000 rs1563333 chr12:120934407 C/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs28595532 0.920 rs115294251 chr4:119772833 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs6460942 0.732 rs73677576 chr7:12286535 G/A cg06484146 chr7:12443880 VWDE -0.54 -4.82 -0.4 4.13e-6 Coronary artery disease; TGCT cis rs752010 0.714 rs6600384 chr1:42085141 A/G cg06885757 chr1:42089581 HIVEP3 -0.25 -4.77 -0.39 5.05e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs4478858 0.684 rs1546375 chr1:31765968 C/T cg07478791 chr1:31886160 SERINC2 -0.48 -4.6 -0.38 1.05e-5 Alcohol dependence; TGCT cis rs7772486 0.840 rs2474355 chr6:146312540 C/G cg05347473 chr6:146136440 FBXO30 0.54 5.17 0.42 9.22e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs611744 0.967 rs671139 chr8:109191260 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs7937682 0.924 rs11213968 chr11:111527629 G/C cg09085632 chr11:111637200 PPP2R1B -1.12 -11.78 -0.73 5.92e-22 Primary sclerosing cholangitis; TGCT cis rs7666738 0.830 rs1896154 chr4:99021161 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9549260 0.564 rs7998086 chr13:41268924 T/C cg21288729 chr13:41239152 FOXO1 0.93 9.21 0.64 1.05e-15 Red blood cell count; TGCT cis rs4819852 0.958 rs2238784 chr22:19972559 G/A cg07821417 chr22:19972146 ARVCF 0.19 4.79 0.4 4.7e-6 Pulse pressure; TGCT cis rs6952808 0.689 rs1107591 chr7:2041638 G/A cg22963979 chr7:1858916 MAD1L1 -0.45 -7.4 -0.55 1.78e-11 Bipolar disorder and schizophrenia; TGCT cis rs330071 0.686 rs4841139 chr8:9249210 C/T cg11995313 chr8:8860691 ERI1 -0.49 -4.68 -0.39 7.31e-6 Acne (severe); TGCT cis rs6570726 1.000 rs6570699 chr6:145920732 G/A cg23711669 chr6:146136114 FBXO30 0.65 5.96 0.47 2.4e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs926938 0.527 rs360583 chr1:115462743 C/T cg12756093 chr1:115239321 AMPD1 0.34 4.95 0.41 2.35e-6 Autism; TGCT cis rs2239547 0.563 rs4687560 chr3:52898121 T/G cg10802521 chr3:52805072 NEK4 -0.59 -5.7 -0.46 8.37e-8 Schizophrenia; TGCT cis rs3617 0.573 rs12638968 chr3:52919447 T/A cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.92 0.4 2.69e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7819412 0.521 rs13256092 chr8:11000377 A/T cg21775007 chr8:11205619 TDH -0.52 -4.55 -0.38 1.24e-5 Triglycerides; TGCT cis rs35264875 0.808 rs2305498 chr11:68866914 G/A cg02660097 chr11:68866761 NA 0.31 4.88 0.4 3.17e-6 Blond vs. brown hair color; TGCT cis rs1570884 0.516 rs7330830 chr13:50167929 T/A cg03651054 chr13:50194643 NA 0.34 5.45 0.44 2.6e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs7584330 0.737 rs12465714 chr2:238365637 C/T cg14458575 chr2:238380390 NA 0.51 8.14 0.59 3.53e-13 Prostate cancer; TGCT cis rs42648 0.790 rs42637 chr7:89969831 A/G cg25739043 chr7:89950458 NA -0.62 -6.1 -0.48 1.24e-8 Homocysteine levels; TGCT cis rs10791323 0.572 rs10791334 chr11:133735810 A/C cg15485101 chr11:133734466 NA 0.43 6.18 0.49 8.32e-9 Childhood ear infection; TGCT cis rs593982 0.920 rs645621 chr11:65490756 T/C cg08755490 chr11:65554678 OVOL1 1.34 7.74 0.57 2.98e-12 Atopic dermatitis; TGCT cis rs2677744 1.000 rs4773 chr15:91463842 G/A cg23684204 chr15:91497937 RCCD1 0.34 5.1 0.42 1.24e-6 Attention deficit hyperactivity disorder; TGCT cis rs62064224 0.791 rs11654833 chr17:30667728 C/T cg25809561 chr17:30822961 MYO1D 0.29 4.73 0.39 6.03e-6 Schizophrenia; TGCT cis rs17594362 0.573 rs79034467 chr13:42147535 C/T cg09909069 chr13:41860793 NA -0.36 -4.45 -0.37 1.86e-5 Multiple sclerosis; TGCT cis rs6901250 1.000 rs6901250 chr6:117114025 A/G cg12892004 chr6:117198278 RFX6 -0.44 -4.92 -0.4 2.69e-6 C-reactive protein levels; TGCT cis rs79349575 0.651 rs4378658 chr17:46993370 G/A cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs9393777 0.513 rs13195210 chr6:26646521 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.935 rs2199956 chr4:1248919 A/G cg13395646 chr4:1353034 KIAA1530 -0.39 -4.76 -0.39 5.34e-6 Obesity-related traits; TGCT cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg10117171 chr1:25599238 RHD -0.35 -5.75 -0.46 6.69e-8 Erythrocyte sedimentation rate; TGCT cis rs10152811 0.675 rs55882120 chr15:86818162 A/G cg21672992 chr15:86584249 NA 0.27 4.55 0.38 1.24e-5 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9788333 0.695 rs12871086 chr13:21890224 A/T cg10411590 chr13:21900810 NA 0.34 4.75 0.39 5.46e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9467773 0.572 rs62394558 chr6:26604650 G/A cg15659132 chr6:26577336 NA 0.84 9.93 0.67 1.82e-17 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs2281588 chr6:28072602 G/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs6121246 0.954 rs73241710 chr20:30424956 G/A cg18721089 chr20:30220636 NA -0.45 -5.0 -0.41 1.9e-6 Mean corpuscular hemoglobin; TGCT cis rs1580019 0.563 rs10486509 chr7:32585443 C/G cg07520158 chr7:32535189 LSM5;AVL9 -0.57 -5.02 -0.41 1.78e-6 Cognitive ability; TGCT cis rs11242417 0.786 rs11746476 chr5:137511540 T/C ch.5.2533981R chr5:137298291 FAM13B -0.39 -4.47 -0.37 1.72e-5 Immune reponse to smallpox (secreted IL-12p40); TGCT cis rs10504229 0.636 rs72649123 chr8:58045789 A/T cg08219700 chr8:58056026 NA 0.29 4.5 0.37 1.54e-5 Developmental language disorder (linguistic errors); TGCT cis rs6964587 0.773 rs17757926 chr7:91987702 T/C cg17063962 chr7:91808500 NA 0.83 8.18 0.59 2.83e-13 Breast cancer; TGCT cis rs1150668 0.799 rs1150707 chr6:28197605 C/T cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.61 -0.38 9.84e-6 Pubertal anthropometrics; TGCT cis rs938554 0.578 rs7663032 chr4:9993838 C/T cg11266682 chr4:10021025 SLC2A9 0.51 5.1 0.42 1.23e-6 Blood metabolite levels; TGCT cis rs35146811 0.735 rs858505 chr7:99819577 G/A cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs7267979 1.000 rs6037121 chr20:25428311 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28595532 0.844 rs80188901 chr4:119500014 C/T cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.15e-11 Cannabis dependence symptom count; TGCT cis rs28595532 0.920 rs116795224 chr4:119734570 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs2016266 0.859 rs10876433 chr12:53734114 G/A cg16917193 chr12:54089295 NA -0.7 -4.62 -0.38 9.55e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg15556689 chr8:8085844 FLJ10661 0.83 8.1 0.59 4.45e-13 Systolic blood pressure; TGCT cis rs2288073 1.000 rs6708328 chr2:24412413 A/G cg02683114 chr2:24398427 C2orf84 -0.25 -5.73 -0.46 7.14e-8 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs10267417 0.544 rs2072185 chr7:19748700 G/A cg05791153 chr7:19748676 TWISTNB 1.33 13.99 0.78 2.88e-27 Night sleep phenotypes; TGCT cis rs7582180 0.790 rs4851288 chr2:100920451 T/C cg14675211 chr2:100938903 LONRF2 0.46 4.52 0.38 1.43e-5 Intelligence (multi-trait analysis); TGCT cis rs12519773 0.526 rs7714485 chr5:92515301 A/C cg04854328 chr5:92914828 FLJ42709 -0.3 -4.58 -0.38 1.12e-5 Migraine; TGCT cis rs941408 0.515 rs2110118 chr19:2775144 T/C cg26465405 chr19:3039745 TLE2 -0.22 -4.52 -0.38 1.44e-5 Total cholesterol levels; TGCT cis rs9549260 0.564 rs7998724 chr13:41324793 G/T cg21288729 chr13:41239152 FOXO1 0.99 9.68 0.66 7.68e-17 Red blood cell count; TGCT cis rs1635 0.655 rs73742544 chr6:28317536 T/A cg15743358 chr6:28303923 ZNF323 -1.3 -4.94 -0.41 2.45e-6 Schizophrenia; TGCT cis rs6540559 1.000 rs6696825 chr1:209982372 A/G cg22029157 chr1:209979665 IRF6 0.78 6.29 0.49 5.01e-9 Cleft lip with or without cleft palate; TGCT cis rs2115630 0.645 rs2292463 chr15:85175750 A/G cg17173187 chr15:85201210 NMB -0.49 -5.99 -0.47 2.15e-8 P wave terminal force; TGCT cis rs13336428 0.730 rs28653458 chr16:1525850 T/C cg26690334 chr16:1524521 CLCN7 -0.4 -6.87 -0.52 2.78e-10 Bone mineral density; TGCT cis rs6540559 0.611 rs926347 chr1:209965193 T/C cg21951975 chr1:209979733 IRF6 0.68 5.3 0.43 5.17e-7 Cleft lip with or without cleft palate; TGCT cis rs1215050 0.755 rs811479 chr4:98727398 A/T cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 1.95e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs765787 0.530 rs12903149 chr15:45539076 G/A cg24006582 chr15:45444508 DUOX1 0.24 5.23 0.43 6.85e-7 Uric acid levels; TGCT trans rs7618501 0.633 rs4688690 chr3:50022292 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.38 0.64 3.95e-16 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.710 rs7572923 chr2:43685109 C/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.77 0.39 5.16e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11096990 0.634 rs10029074 chr4:39292502 T/G cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs7772486 0.846 rs1331636 chr6:146338826 T/C cg23711669 chr6:146136114 FBXO30 0.88 9.67 0.66 7.78e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg07167872 chr1:205819463 PM20D1 0.68 9.92 0.67 2.01e-17 Menarche (age at onset); TGCT cis rs34014631 0.786 rs75773111 chr10:103658180 T/C cg22630918 chr10:102748988 C10orf2 0.42 4.82 0.4 4.15e-6 Coronary artery calcification; TGCT cis rs7954584 0.616 rs10743185 chr12:122356435 G/A cg10207240 chr12:122356781 WDR66 0.34 4.68 0.39 7.53e-6 Mean corpuscular volume; TGCT cis rs6992820 0.967 rs6996402 chr8:56752230 G/C cg06880721 chr8:56792545 LYN -0.55 -4.71 -0.39 6.4e-6 Mean platelet volume; TGCT cis rs7267979 1.000 rs2387880 chr20:25377787 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3774830 1.000 rs6827240 chr4:5440224 G/T cg26943120 chr4:5472116 STK32B 0.21 4.62 0.38 9.37e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs28595532 0.841 rs116452272 chr4:119770802 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs4499344 0.633 rs259271 chr19:33157100 A/G cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT cis rs7954584 0.520 rs1169095 chr12:122465738 G/A cg13699009 chr12:122356056 WDR66 -0.22 -4.59 -0.38 1.05e-5 Mean corpuscular volume; TGCT cis rs6951245 1.000 rs11763793 chr7:1094342 A/G cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs986417 0.748 rs1955700 chr14:61046481 A/G cg18240143 chr14:60952599 C14orf39 0.82 4.51 0.38 1.46e-5 Gut microbiota (bacterial taxa); TGCT cis rs1552244 0.572 rs12107622 chr3:10171898 T/A cg00149659 chr3:10157352 C3orf10 1.2 7.56 0.56 7.9e-12 Alzheimer's disease; TGCT cis rs2153535 0.623 rs6597338 chr6:8533508 A/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs6951245 0.554 rs78999139 chr7:1138525 G/A cg03188948 chr7:1209495 NA 0.52 5.4 0.44 3.29e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs35934224 0.891 rs13054713 chr22:19867914 C/A cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.08e-7 Glaucoma (primary open-angle); TGCT cis rs7618915 0.547 rs1561337 chr3:52659963 C/T cg07507251 chr3:52567010 NT5DC2 0.49 7.06 0.54 1.06e-10 Bipolar disorder; TGCT cis rs9393777 0.513 rs9379907 chr6:26654318 C/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT trans rs7819412 0.511 rs35558344 chr8:11434232 C/T cg06636001 chr8:8085503 FLJ10661 -0.8 -7.51 -0.56 1.03e-11 Triglycerides; TGCT cis rs2197308 0.765 rs12370231 chr12:37917881 T/C cg26384229 chr12:38710491 ALG10B 0.88 7.7 0.57 3.71e-12 Morning vs. evening chronotype; TGCT cis rs2204008 0.645 rs9989043 chr12:38238505 G/A cg26384229 chr12:38710491 ALG10B -0.52 -4.46 -0.37 1.8e-5 Bladder cancer; TGCT cis rs11098499 0.615 rs28850368 chr4:120554313 G/A cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs7772486 0.875 rs2748490 chr6:146329681 G/T cg23711669 chr6:146136114 FBXO30 0.82 8.92 0.63 5.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs62103177 0.673 rs7242867 chr18:77603270 A/T cg12964065 chr18:77638022 KCNG2 0.33 4.63 0.38 9.06e-6 Opioid sensitivity; TGCT cis rs7651039 0.641 rs2455823 chr3:15666856 T/C cg16303742 chr3:15540471 COLQ 0.25 4.56 0.38 1.19e-5 Coronary heart disease; TGCT cis rs11105298 0.891 rs4842661 chr12:89930399 A/G cg00757033 chr12:89920650 WDR51B 0.29 4.46 0.37 1.78e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7677751 0.806 rs6850748 chr4:55099164 T/G cg17187183 chr4:55093834 PDGFRA 0.55 7.06 0.54 1.05e-10 Corneal astigmatism; TGCT cis rs11578119 0.933 rs3923079 chr1:170462467 A/G cg09767346 chr1:170501363 GORAB -0.68 -5.41 -0.44 3.18e-7 Male-pattern baldness; TGCT cis rs12468226 1.000 rs111542497 chr2:203195092 G/T cg26506821 chr2:202639771 ALS2 0.32 4.46 0.37 1.84e-5 Urate levels; TGCT cis rs3812049 0.737 rs1112956 chr5:127433798 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.63 -5.8 -0.46 5.2e-8 Lymphocyte counts;Red cell distribution width; TGCT cis rs3809566 0.963 rs4775608 chr15:63331940 A/G cg08198488 chr15:63333792 TPM1 -0.35 -5.23 -0.43 7e-7 Platelet count; TGCT cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg26818010 chr10:134567672 INPP5A -0.39 -5.51 -0.44 1.96e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2404602 0.692 rs67010831 chr15:76965308 T/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs116095464 0.558 rs6555056 chr5:226222 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs2952156 1.000 rs2643194 chr17:37853048 C/T cg19468946 chr17:37922297 IKZF3 -0.19 -4.46 -0.37 1.82e-5 Asthma; TGCT cis rs7091068 0.671 rs604489 chr10:95405408 T/C cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs4409675 0.549 rs72872888 chr1:28239809 G/A cg23691781 chr1:28212827 C1orf38 0.28 5.82 0.46 4.66e-8 Corneal astigmatism; TGCT cis rs6951245 1.000 rs2363286 chr7:1091625 A/G cg03188948 chr7:1209495 NA 0.53 4.86 0.4 3.5e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.830 rs10031190 chr4:98908683 C/A cg17366294 chr4:99064904 C4orf37 0.71 7.33 0.55 2.63e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2486012 0.678 rs3011218 chr1:44303329 T/A cg12908607 chr1:44402522 ARTN -0.71 -5.54 -0.45 1.77e-7 Intelligence (multi-trait analysis); TGCT cis rs9486715 0.929 rs2025044 chr6:97067028 A/G cg06623918 chr6:96969491 KIAA0776 -1.09 -13.44 -0.77 5.74e-26 Headache; TGCT cis rs13242816 1.000 rs13221364 chr7:116083544 C/T cg02799643 chr7:116139180 CAV2 -0.5 -5.4 -0.44 3.32e-7 P wave duration; TGCT cis rs2486012 1.000 rs2906467 chr1:44320476 C/A cg12908607 chr1:44402522 ARTN -0.72 -5.68 -0.45 8.89e-8 Intelligence (multi-trait analysis); TGCT cis rs11792861 0.781 rs11789252 chr9:111762010 A/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.69 0.39 6.99e-6 Menarche (age at onset); TGCT cis rs7582180 0.629 rs11685406 chr2:100946638 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.861 rs7503514 chr17:37669884 G/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.88 -0.4 3.2e-6 Glomerular filtration rate (creatinine); TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg14893161 chr1:205819251 PM20D1 0.53 7.2 0.54 5.19e-11 Menarche (age at onset); TGCT cis rs4845570 0.850 rs4618976 chr1:151766588 A/G cg07092448 chr1:151763213 TDRKH 1.16 9.41 0.65 3.38e-16 Coronary artery disease; TGCT cis rs1552244 0.935 rs7621551 chr3:10114205 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs889312 0.500 rs832566 chr5:56151744 C/T cg24531977 chr5:56204891 C5orf35 -0.48 -4.78 -0.39 4.9e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs644148 0.967 rs613876 chr19:44968788 T/C cg15540054 chr19:45004280 ZNF180 -0.59 -5.18 -0.42 8.71e-7 Personality dimensions; TGCT cis rs7267979 1.000 rs2500446 chr20:25339664 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6570726 0.935 rs12663205 chr6:145818378 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10419226 0.625 rs12974777 chr19:18765663 C/T cg14292368 chr19:18793705 CRTC1 -0.49 -5.42 -0.44 2.98e-7 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs986417 1.000 rs986417 chr14:60858761 C/T cg23984976 chr14:60032921 C14orf38 -0.5 -4.63 -0.38 9.07e-6 Gut microbiota (bacterial taxa); TGCT cis rs12541335 0.639 rs7003478 chr8:22201123 A/G cg02788857 chr8:22132959 PIWIL2 0.28 5.15 0.42 9.82e-7 Hypertriglyceridemia; TGCT cis rs688020 1.000 rs673500 chr7:4229445 C/G cg24441899 chr7:4244372 SDK1 -0.39 -4.94 -0.41 2.43e-6 Liver fibrosis in pediatric non-alcoholic fatty acid liver disease; TGCT cis rs72945132 0.619 rs34053053 chr11:70260598 C/T cg00319359 chr11:70116639 PPFIA1 0.99 6.52 0.51 1.56e-9 Coronary artery disease; TGCT cis rs2197308 0.715 rs11181816 chr12:37911626 A/G cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs2836974 0.931 rs13047663 chr21:40708818 C/T cg11644478 chr21:40555479 PSMG1 0.9 8.01 0.58 7.21e-13 Cognitive function; TGCT cis rs1799949 0.965 rs799916 chr17:41243190 G/T cg19454999 chr17:41278357 BRCA1;NBR2 -0.39 -4.61 -0.38 1e-5 Menopause (age at onset); TGCT cis rs9911578 0.935 rs9911753 chr17:56983174 G/A cg05425664 chr17:57184151 TRIM37 -0.56 -5.42 -0.44 2.99e-7 Intelligence (multi-trait analysis); TGCT cis rs7547997 0.615 rs73029766 chr1:158320989 G/A cg07950803 chr1:158223934 CD1A 0.31 4.71 0.39 6.42e-6 QRS duration; TGCT cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs2549003 0.934 rs2549006 chr5:131827065 A/G cg21138405 chr5:131827807 IRF1 -0.18 -4.46 -0.37 1.82e-5 Asthma (sex interaction); TGCT cis rs425277 0.500 rs908744 chr1:2038893 G/A cg03732007 chr1:2071316 PRKCZ -0.27 -5.96 -0.47 2.42e-8 Height; TGCT cis rs13217239 0.646 rs12209886 chr6:26984757 G/A cg07220782 chr6:26987966 LOC100270746;C6orf41 0.4 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs12142240 0.698 rs72890727 chr1:46860237 G/A cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs7940866 0.903 rs1820353 chr11:130870765 A/G cg05962950 chr11:130786565 SNX19 0.62 6.14 0.48 1.05e-8 Schizophrenia; TGCT cis rs910187 0.678 rs3818013 chr20:45816639 A/G cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs9457247 0.967 rs425039 chr6:167410527 C/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs1799949 0.930 rs35292991 chr17:41334016 C/A cg05368731 chr17:41323189 NBR1 1.17 13.48 0.77 4.54e-26 Menopause (age at onset); TGCT cis rs11249608 0.636 rs62393070 chr5:178447943 A/G cg21905437 chr5:178450457 ZNF879 0.45 4.53 0.38 1.38e-5 Pubertal anthropometrics; TGCT cis rs138249 0.902 rs138240 chr22:50564181 A/C cg24864161 chr22:50528282 MOV10L1 -0.47 -5.02 -0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs4689592 0.503 rs3857180 chr4:7073899 T/G cg25660036 chr4:7070649 GRPEL1 0.59 4.62 0.38 9.55e-6 Monocyte percentage of white cells; TGCT cis rs2456568 0.548 rs10501809 chr11:93666263 C/G cg26875233 chr11:93583750 C11orf90 -0.43 -5.25 -0.43 6.44e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10791097 0.720 rs6590517 chr11:130733505 C/T cg05962950 chr11:130786565 SNX19 0.9 10.98 0.7 5.34e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs478304 0.903 rs1151502 chr11:65503485 G/C cg27068330 chr11:65405492 SIPA1 0.75 7.39 0.55 1.93e-11 Acne (severe); TGCT trans rs208520 1.000 rs208536 chr6:66963440 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.88 -8.21 -0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg25036284 chr2:26402008 FAM59B -0.65 -5.18 -0.42 8.8e-7 Gut microbiome composition (summer); TGCT cis rs2404602 0.716 rs17364076 chr15:76760891 C/T cg22467129 chr15:76604101 ETFA -0.55 -6.71 -0.52 6.16e-10 Blood metabolite levels; TGCT cis rs6426558 0.559 rs485234 chr1:227317747 A/G cg10327440 chr1:227177885 CDC42BPA 0.58 6.91 0.53 2.21e-10 Neutrophil percentage of white cells; TGCT cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT trans rs12599106 0.629 rs1391904 chr16:34548934 C/T cg18110333 chr6:292329 DUSP22 -0.68 -7.5 -0.56 1.08e-11 Menopause (age at onset); TGCT cis rs2153535 0.541 rs4637688 chr6:8446501 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.71 0.46 7.86e-8 Motion sickness; TGCT cis rs950169 0.580 rs11634320 chr15:85172183 A/C cg12863693 chr15:85201151 NMB -0.46 -5.56 -0.45 1.6e-7 Schizophrenia; TGCT cis rs9611565 0.512 rs2899349 chr22:42164660 T/C cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs2070488 0.775 rs9838614 chr3:38537671 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.66 -6.0 -0.47 2.05e-8 Electrocardiographic conduction measures; TGCT cis rs11122272 0.735 rs2749709 chr1:231530476 G/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT cis rs10751667 0.961 rs10794358 chr11:985547 C/T cg06064525 chr11:970664 AP2A2 -0.31 -6.16 -0.48 9.52e-9 Alzheimer's disease (late onset); TGCT cis rs10114408 0.959 rs10125611 chr9:96646491 G/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6570726 0.620 rs367693 chr6:145815949 G/A cg23711669 chr6:146136114 FBXO30 0.71 6.51 0.5 1.72e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs76473307 1.000 rs116859592 chr20:57419988 T/C cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs2242116 0.793 rs9855938 chr3:46957298 G/A cg27129171 chr3:47204927 SETD2 0.63 6.13 0.48 1.08e-8 Birth weight; TGCT cis rs17152411 0.895 rs7086128 chr10:126587373 A/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs9653442 0.545 rs4490209 chr2:100766711 C/G cg22139774 chr2:100720529 AFF3 -0.35 -5.56 -0.45 1.57e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11792861 0.926 rs17628095 chr9:111889172 A/G cg14432460 chr9:111696404 IKBKAP;C9orf6 -0.49 -4.58 -0.38 1.1e-5 Menarche (age at onset); TGCT cis rs896854 0.902 rs896852 chr8:95960886 G/T cg16049864 chr8:95962084 TP53INP1 -0.76 -11.14 -0.71 2.13e-20 Type 2 diabetes; TGCT cis rs116161686 0.500 rs55871867 chr1:210051029 A/G cg04352962 chr1:209979756 IRF6 0.63 4.48 0.37 1.65e-5 Coronary artery disease; TGCT cis rs7226408 0.857 rs56049218 chr18:34429685 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs6450176 1.000 rs6876198 chr5:53303595 A/G ch.5.1024479R chr5:53302184 ARL15 -0.51 -4.58 -0.38 1.13e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2721195 0.874 rs2721197 chr8:145727705 A/G cg15320075 chr8:145703422 NA 0.69 6.75 0.52 5.13e-10 Age at first birth; TGCT cis rs2637266 1.000 rs10219023 chr10:78364537 G/A cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs7833790 1.000 rs28696138 chr8:82770794 G/A cg17211192 chr8:82754475 SNX16 1.06 8.51 0.61 4.89e-14 Diastolic blood pressure; TGCT cis rs40363 0.645 rs250633 chr16:3523002 C/T cg05754148 chr16:3507555 NAT15 0.41 4.9 0.4 2.9e-6 Tuberculosis; TGCT cis rs10206020 0.759 rs11903889 chr2:1576601 C/T cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs9527 0.544 rs1572578 chr10:104822431 C/G cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs2290402 0.536 rs56080039 chr4:886519 G/A cg23332689 chr4:987652 IDUA;SLC26A1 0.33 5.0 0.41 1.94e-6 Type 2 diabetes; TGCT cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.72 -7.32 -0.55 2.76e-11 Prudent dietary pattern; TGCT cis rs644799 0.965 rs573758 chr11:95539591 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9814567 1.000 rs6802654 chr3:134217072 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7095607 0.777 rs7919994 chr10:69931144 T/G cg18986048 chr10:69913749 MYPN 0.46 5.24 0.43 6.63e-7 Lung function (FVC); TGCT cis rs10504229 0.728 rs17804335 chr8:58151428 G/T cg24829409 chr8:58192753 C8orf71 0.59 4.97 0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs1023500 0.573 rs133377 chr22:42466950 C/T cg15557168 chr22:42548783 NA -0.22 -5.58 -0.45 1.47e-7 Schizophrenia; TGCT cis rs6952808 0.792 rs2056481 chr7:1955435 A/G cg04267008 chr7:1944627 MAD1L1 -0.34 -4.45 -0.37 1.87e-5 Bipolar disorder and schizophrenia; TGCT cis rs6733011 0.508 rs4850889 chr2:99521385 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.44 -0.44 2.74e-7 Bipolar disorder; TGCT cis rs7119 0.679 rs34075648 chr15:77847802 G/C cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.11 0.48 1.19e-8 Bipolar disorder; TGCT cis rs968567 0.539 rs174549 chr11:61571382 A/G cg19610905 chr11:61596333 FADS2 0.99 10.68 0.69 2.87e-19 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs9788682 0.694 rs10851906 chr15:78774676 A/G cg24631222 chr15:78858424 CHRNA5 0.61 4.53 0.38 1.37e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs910316 1.000 rs3742780 chr14:75505008 G/C cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.36e-19 Height; TGCT cis rs73198271 0.694 rs114184516 chr8:8647082 A/G cg06671706 chr8:8559999 CLDN23 -0.35 -4.5 -0.37 1.52e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs36051895 0.632 rs7850425 chr9:5170645 G/T cg02405213 chr9:5042618 JAK2 -0.72 -9.46 -0.65 2.63e-16 Pediatric autoimmune diseases; TGCT cis rs2832191 0.740 rs2012645 chr21:30445961 G/A cg24692254 chr21:30365293 RNF160 0.98 11.36 0.71 6.16e-21 Dental caries; TGCT cis rs2033711 0.870 rs1465789 chr19:58946056 C/T cg12042659 chr19:58951599 ZNF132 0.52 4.6 0.38 1.03e-5 Uric acid clearance; TGCT cis rs10992471 0.603 rs6479422 chr9:95190694 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.94 -0.47 2.62e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10504229 0.775 rs17804888 chr8:58158315 G/T cg21724239 chr8:58056113 NA -0.39 -4.65 -0.39 8.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.875 rs1125461 chr6:146417653 C/T cg23711669 chr6:146136114 FBXO30 0.89 9.5 0.65 2.1e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs1865760 0.865 rs9467641 chr6:25947236 T/C cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT cis rs6121246 0.697 rs6088856 chr20:30226543 C/G cg13852791 chr20:30311386 BCL2L1 0.73 4.75 0.39 5.43e-6 Mean corpuscular hemoglobin; TGCT cis rs12220898 0.749 rs10857456 chr10:50474756 A/G cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.85e-5 Inflammatory biomarkers; TGCT cis rs71435601 0.628 rs1652419 chr2:21385649 C/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs10256972 0.521 rs7811577 chr7:1102829 C/G cg18402987 chr7:1209562 NA 0.4 4.6 0.38 1.04e-5 Longevity;Endometriosis; TGCT cis rs710216 0.917 rs1681859 chr1:43411829 G/A cg03128534 chr1:43423976 SLC2A1 0.61 4.46 0.37 1.81e-5 Red cell distribution width; TGCT cis rs8016982 0.609 rs8009519 chr14:81702503 C/G cg01989461 chr14:81687754 GTF2A1 0.84 8.65 0.61 2.22e-14 Schizophrenia; TGCT cis rs2153535 0.580 rs1932285 chr6:8477719 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs425277 0.527 rs3107144 chr1:2045380 C/A cg03732007 chr1:2071316 PRKCZ -0.24 -5.38 -0.44 3.57e-7 Height; TGCT cis rs992157 0.804 rs6758540 chr2:219138625 A/G cg00012203 chr2:219082015 ARPC2 -0.78 -7.64 -0.57 5.16e-12 Colorectal cancer; TGCT cis rs76878669 0.606 rs1785639 chr11:66100430 G/A cg18002602 chr11:66138449 SLC29A2 0.52 6.5 0.5 1.76e-9 Educational attainment (years of education); TGCT cis rs9527 0.590 rs34104646 chr10:104896078 T/A cg15744005 chr10:104629667 AS3MT -0.43 -4.94 -0.41 2.45e-6 Arsenic metabolism; TGCT cis rs77972916 0.536 rs62137421 chr2:43594091 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.33 -4.61 -0.38 1.01e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg18402987 chr7:1209562 NA 0.74 6.19 0.49 7.92e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs929354 0.772 rs6969244 chr7:157004012 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.77 -0.62 1.19e-14 Body mass index; TGCT cis rs6969780 0.673 rs2301721 chr7:27196113 C/T cg04321618 chr7:27170880 HOXA4 -0.52 -5.18 -0.42 8.67e-7 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs11098499 0.863 rs3822191 chr4:120428101 A/T cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.36e-9 Corneal astigmatism; TGCT cis rs425277 0.606 rs262669 chr1:2082489 A/G cg24578937 chr1:2090814 PRKCZ -0.26 -6.91 -0.53 2.21e-10 Height; TGCT cis rs9660992 0.710 rs1768586 chr1:205238275 A/G cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs7829975 0.688 rs7826660 chr8:8379107 C/A cg15556689 chr8:8085844 FLJ10661 0.67 6.2 0.49 7.84e-9 Mood instability; TGCT cis rs476633 0.691 rs2164996 chr15:41536624 A/G cg11362250 chr15:42265079 EHD4 -0.35 -4.48 -0.37 1.68e-5 Glomerular filtration rate (creatinine); TGCT cis rs2013441 1.000 rs2526483 chr17:20112216 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs68170813 0.559 rs77150993 chr7:106817100 G/T cg02696742 chr7:106810147 HBP1 -0.7 -6.05 -0.48 1.59e-8 Coronary artery disease; TGCT cis rs3091242 0.933 rs61775167 chr1:25780893 A/G cg00786635 chr1:25594202 NA -0.52 -5.56 -0.45 1.59e-7 Erythrocyte sedimentation rate; TGCT cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs597539 0.552 rs6591360 chr11:68718669 G/T cg21963583 chr11:68658836 MRPL21 0.36 5.99 0.47 2.1e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs72615157 0.613 rs56089143 chr7:99819844 G/A cg00814883 chr7:100076585 TSC22D4 -0.55 -5.42 -0.44 3.01e-7 Lung function (FEV1/FVC); TGCT cis rs763014 0.966 rs4984903 chr16:680695 A/G cg09263875 chr16:632152 PIGQ 0.31 6.89 0.53 2.52e-10 Height; TGCT cis rs9993613 0.808 rs1401153 chr4:73432895 C/T cg15102770 chr4:73434591 ADAMTS3 0.51 4.57 0.38 1.16e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs597539 0.552 rs6591360 chr11:68718669 G/T cg06028808 chr11:68637592 NA 0.53 6.87 0.52 2.78e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.6 -0.38 1.01e-5 Schizophrenia; TGCT cis rs68170813 0.559 rs7779062 chr7:106880195 T/A cg02696742 chr7:106810147 HBP1 -0.66 -5.51 -0.44 1.94e-7 Coronary artery disease; TGCT cis rs7647973 0.593 rs1799844 chr3:49847642 G/A cg03060546 chr3:49711283 APEH -0.62 -5.23 -0.43 6.88e-7 Menarche (age at onset); TGCT cis rs4780401 0.609 rs4781142 chr16:11808806 T/C cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs950169 1.000 rs950169 chr15:84706461 C/T cg11189052 chr15:85197271 WDR73 0.7 6.02 0.48 1.82e-8 Schizophrenia; TGCT cis rs2862064 0.932 rs1809941 chr5:156482459 G/T cg12943317 chr5:156479607 HAVCR1 -0.48 -6.14 -0.48 1.05e-8 Platelet count; TGCT cis rs873946 0.517 rs2803990 chr10:134560340 A/G cg17054783 chr10:134559939 INPP5A 0.23 4.64 0.38 8.63e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs3829109 0.564 rs10781511 chr9:139280766 G/A cg13741927 chr9:139327495 INPP5E -0.23 -4.88 -0.4 3.19e-6 Peak insulin response;Acute insulin response; TGCT cis rs2115630 0.645 rs6496284 chr15:85178270 A/G cg12863693 chr15:85201151 NMB -0.36 -4.71 -0.39 6.42e-6 P wave terminal force; TGCT cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg05738196 chr6:26577821 NA 0.88 10.63 0.69 3.68e-19 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs1153858 0.943 rs7402632 chr15:45701913 A/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.67 0.45 9.65e-8 Homoarginine levels; TGCT cis rs6060960 0.502 rs6057968 chr20:30082779 A/T cg18721089 chr20:30220636 NA -0.55 -5.74 -0.46 6.72e-8 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT trans rs1814175 0.645 rs1722000 chr11:49917928 A/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs60871478 0.730 rs73042471 chr7:927762 G/A cg15782153 chr7:917662 C7orf20 0.55 4.89 0.4 3.11e-6 Cerebrospinal P-tau181p levels; TGCT cis rs7666738 0.830 rs10856936 chr4:99011319 T/C cg17366294 chr4:99064904 C4orf37 0.67 6.97 0.53 1.69e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4455778 0.759 rs1860514 chr7:49006428 G/T cg26309511 chr7:48887640 NA -0.5 -5.98 -0.47 2.22e-8 Lung cancer in never smokers; TGCT cis rs7829975 0.774 rs35431455 chr8:8673736 T/C cg15556689 chr8:8085844 FLJ10661 0.68 6.21 0.49 7.2e-9 Mood instability; TGCT cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg10263370 chr3:44754102 ZNF502 -0.4 -4.8 -0.4 4.4e-6 Depressive symptoms; TGCT cis rs12478296 1.000 rs57603292 chr2:243028537 G/A cg06360820 chr2:242988706 NA -0.81 -5.39 -0.44 3.36e-7 Obesity-related traits; TGCT cis rs2180341 0.920 rs6916990 chr6:127698759 G/A cg24812749 chr6:127587940 RNF146 0.99 7.63 0.57 5.24e-12 Breast cancer; TGCT cis rs916888 0.773 rs199447 chr17:44812188 C/T cg16228356 chr17:43848958 NA -0.26 -4.53 -0.38 1.37e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7223966 1.000 rs9899788 chr17:61756384 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.05 0.41 1.51e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9527 0.622 rs12779263 chr10:104886533 G/T cg04362960 chr10:104952993 NT5C2 0.74 6.23 0.49 6.77e-9 Arsenic metabolism; TGCT cis rs3806843 0.576 rs265316 chr5:140290843 T/C cg07102913 chr5:140593443 PCDHB13 -0.48 -4.71 -0.39 6.57e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7631605 0.905 rs11714716 chr3:37269678 A/G cg17445812 chr3:36986805 TRANK1 0.22 4.86 0.4 3.43e-6 Cerebrospinal P-tau181p levels; TGCT cis rs1395 0.778 rs1978881 chr2:27400850 C/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.65 9.03 0.63 2.73e-15 Blood metabolite levels; TGCT cis rs735396 0.694 rs2264750 chr12:121450165 C/T cg02403541 chr12:121454288 C12orf43 0.77 7.48 0.56 1.16e-11 N-glycan levels; TGCT cis rs7772486 0.686 rs6570701 chr6:145954090 A/G cg05347473 chr6:146136440 FBXO30 0.48 4.56 0.38 1.19e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs651907 0.557 rs62284199 chr3:101478531 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.34 0.68 1.93e-18 Colorectal cancer; TGCT cis rs10504229 0.679 rs56040464 chr8:58131603 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs611744 0.870 rs57723916 chr8:109191433 A/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT trans rs1814175 0.645 rs7115592 chr11:50013243 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs6964587 1.000 rs34043009 chr7:91578447 T/C cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs7647973 1.000 rs940045 chr3:49449638 G/A cg05785598 chr3:49045655 WDR6 0.37 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs25422 0.938 rs7356858 chr6:118765814 G/C cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Renal cell carcinoma; TGCT cis rs9611565 0.512 rs139572 chr22:42214532 C/T cg03806693 chr22:41940476 POLR3H -1.04 -10.57 -0.69 5.2e-19 Vitiligo; TGCT trans rs7819412 0.807 rs10105315 chr8:10932203 G/C cg15556689 chr8:8085844 FLJ10661 -0.81 -7.79 -0.57 2.36e-12 Triglycerides; TGCT cis rs4804368 1.000 rs12460089 chr19:7190716 T/C cg04811526 chr19:8009138 TIMM44 0.52 4.5 0.38 1.52e-5 Renal cell carcinoma; TGCT cis rs13242816 1.000 rs13247015 chr7:116095623 A/C cg16553024 chr7:116138462 CAV2 -0.46 -5.18 -0.42 8.58e-7 P wave duration; TGCT cis rs2762353 0.574 rs9467573 chr6:25704190 C/A cg03264133 chr6:25882463 NA 0.86 8.5 0.61 5.01e-14 Blood metabolite levels; TGCT cis rs433598 0.765 rs163268 chr16:20660553 A/G cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -4.92 -0.4 2.68e-6 Schizophrenia; TGCT cis rs7746199 0.736 rs17693963 chr6:27710165 A/C cg10876282 chr6:28092338 ZSCAN16 0.95 4.95 0.41 2.4e-6 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs9807989 0.839 rs4988958 chr2:102968285 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg17054783 chr10:134559939 INPP5A 0.24 4.83 0.4 3.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs2637266 0.703 rs6480836 chr10:78446866 C/T cg18941641 chr10:78392320 NA 0.4 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs9517302 0.544 rs2281766 chr13:99098882 A/C cg22223119 chr13:99095684 FARP1 -0.6 -6.41 -0.5 2.71e-9 Obesity-related traits; TGCT cis rs1401999 0.650 rs3792585 chr3:183646222 A/G cg01324343 chr3:183735012 ABCC5 0.67 7.98 0.58 8.16e-13 Anterior chamber depth; TGCT cis rs8016982 0.698 rs12590764 chr14:81704417 G/A cg01989461 chr14:81687754 GTF2A1 0.77 7.16 0.54 6.37e-11 Schizophrenia; TGCT cis rs7572733 0.534 rs700673 chr2:198692929 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs2762353 0.808 rs1165180 chr6:25826347 A/T cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.63e-9 Blood metabolite levels; TGCT cis rs4788570 0.513 rs2113223 chr16:71607915 A/G cg06353428 chr16:71660113 MARVELD3 -1.29 -10.45 -0.68 1e-18 Intelligence (multi-trait analysis); TGCT cis rs8177253 1.000 rs6762719 chr3:133480817 A/G cg20276088 chr3:133502917 NA -0.24 -5.06 -0.41 1.5e-6 Iron status biomarkers; TGCT cis rs2842992 0.830 rs2758352 chr6:160122921 A/G cg11366901 chr6:160182831 ACAT2 1.01 6.67 0.51 7.61e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs7937682 0.924 rs4630327 chr11:111539327 C/T cg09085632 chr11:111637200 PPP2R1B 1.11 12.06 0.73 1.25e-22 Primary sclerosing cholangitis; TGCT cis rs9325144 0.505 rs6582691 chr12:38806894 T/C cg26384229 chr12:38710491 ALG10B -0.83 -7.83 -0.58 1.89e-12 Morning vs. evening chronotype; TGCT cis rs3796352 1.000 rs11712653 chr3:53070875 A/C cg12962167 chr3:53033115 SFMBT1 -0.44 -4.97 -0.41 2.17e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7646507 0.826 rs13071639 chr3:172546930 C/T cg10532262 chr3:172428426 NCEH1 0.92 4.69 0.39 7.21e-6 Obesity-related traits; TGCT cis rs10504229 0.683 rs903702 chr8:58128557 T/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs8180040 0.620 rs9858443 chr3:47086048 G/A cg27129171 chr3:47204927 SETD2 0.71 8.55 0.61 3.9e-14 Colorectal cancer; TGCT cis rs10504229 1.000 rs17805656 chr8:58180318 T/C cg20607798 chr8:58055168 NA 0.45 4.59 0.38 1.06e-5 Developmental language disorder (linguistic errors); TGCT cis rs7208859 0.673 rs216440 chr17:28928309 A/T cg19761014 chr17:28927070 LRRC37B2 0.53 4.63 0.38 9.04e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs7176093 0.665 rs17581281 chr15:86386197 C/T cg03164243 chr17:17717894 MIR33B;SREBF1 0.38 6.92 0.53 2.18e-10 Aging traits; TGCT cis rs9595066 0.941 rs9533777 chr13:44708720 C/T cg04068111 chr13:44716778 NA 0.47 4.6 0.38 1.04e-5 Schizophrenia; TGCT trans rs66573146 1.000 rs55913461 chr4:7017509 C/T cg07817883 chr1:32538562 TMEM39B 1.69 8.36 0.6 1.1e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.708 rs7406783 chr17:29689980 A/G cg24425628 chr17:29625626 OMG;NF1 0.39 5.52 0.44 1.87e-7 Hip circumference; TGCT cis rs113577745 0.725 rs41264179 chr2:10102735 T/C cg17603321 chr2:9696605 ADAM17 -1.15 -5.09 -0.42 1.31e-6 Breast cancer; TGCT cis rs6770219 0.516 rs7632528 chr3:186134307 C/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg11905131 chr22:24372483 LOC391322 -0.95 -11.19 -0.71 1.64e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg19570321 chr11:63258214 HRASLS5 0.44 4.87 0.4 3.35e-6 Platelet count; TGCT cis rs28595532 0.920 rs56212415 chr4:119737731 C/T cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs2688608 0.620 rs11000767 chr10:75516626 G/T cg23231163 chr10:75533350 FUT11 -0.28 -4.86 -0.4 3.51e-6 Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs7833790 1.000 rs7833790 chr8:82731157 T/C cg27398817 chr8:82754497 SNX16 -0.8 -5.98 -0.47 2.2e-8 Diastolic blood pressure; TGCT cis rs10779751 1.000 rs12124983 chr1:11286178 C/T cg08854313 chr1:11322531 MTOR -0.92 -10.28 -0.68 2.6e-18 Body mass index; TGCT cis rs9527 0.615 rs12248123 chr10:104735366 A/G cg04362960 chr10:104952993 NT5C2 0.67 5.69 0.45 8.72e-8 Arsenic metabolism; TGCT cis rs9581857 0.725 rs9581853 chr13:28016236 T/C cg22138327 chr13:27999177 GTF3A 0.77 5.47 0.44 2.33e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs10465746 0.725 rs2024591 chr1:84329235 C/T cg10977910 chr1:84465055 TTLL7 0.66 6.61 0.51 1.03e-9 Obesity-related traits; TGCT cis rs10504229 0.679 rs17804870 chr8:58158071 A/G cg08280861 chr8:58055591 NA 0.44 4.6 0.38 1.01e-5 Developmental language disorder (linguistic errors); TGCT cis rs9549260 0.709 rs4943795 chr13:41173433 C/T cg21288729 chr13:41239152 FOXO1 -0.94 -8.14 -0.59 3.64e-13 Red blood cell count; TGCT cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.52 0.44 1.86e-7 Height; TGCT cis rs3806843 0.576 rs246047 chr5:140328337 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7937682 0.564 rs11600652 chr11:111754368 A/T cg09085632 chr11:111637200 PPP2R1B 0.92 8.7 0.62 1.7e-14 Primary sclerosing cholangitis; TGCT cis rs9677476 0.516 rs2303349 chr2:232030861 A/G cg07929768 chr2:232055508 NA 0.33 5.21 0.42 7.7300000000000005e-07 Food antigen IgG levels; TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg15242686 chr22:24348715 GSTTP1 0.47 5.3 0.43 5.14e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2956278 0.717 rs7976572 chr12:84684995 A/T cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs2688608 0.869 rs2250140 chr10:75612881 T/C cg19442545 chr10:75533431 FUT11 -0.31 -4.94 -0.41 2.48e-6 Inflammatory bowel disease; TGCT cis rs4253772 0.591 rs6008545 chr22:46686375 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.66 4.77 0.39 5.13e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs4478858 0.735 rs6670067 chr1:31842947 C/T cg07478791 chr1:31886160 SERINC2 -0.49 -4.66 -0.39 7.9e-6 Alcohol dependence; TGCT cis rs1865760 0.566 rs2032449 chr6:26026599 G/C cg16482183 chr6:26056742 HIST1H1C 0.59 5.14 0.42 1.04e-6 Height; TGCT cis rs6089829 0.851 rs10854168 chr20:61669550 A/G cg08564027 chr20:61660810 NA 0.37 5.98 0.47 2.26e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs597539 0.652 rs674654 chr11:68698762 G/T cg06028808 chr11:68637592 NA 0.53 6.86 0.52 2.89e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs61990749 0.597 rs28534379 chr14:78172140 G/A cg02301378 chr14:78227641 SNW1;C14orf178 -0.63 -4.62 -0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs35146811 0.735 rs1727139 chr7:99815367 C/T cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs17133449 0.718 rs11252674 chr10:4753422 C/T cg04530666 chr10:3759553 NA -0.3 -5.04 -0.41 1.58e-6 Major depressive disorder; TGCT cis rs9383153 1.000 rs9383153 chr6:16343056 A/G cg06493612 chr6:15502050 JARID2 0.59 4.88 0.4 3.16e-6 Gambling; TGCT cis rs7666738 0.861 rs5010991 chr4:98972179 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs72949976 0.734 rs62189579 chr2:214016984 T/A cg08319019 chr2:214017104 IKZF2 -0.83 -7.53 -0.56 8.95e-12 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs7666738 0.893 rs11729640 chr4:99052699 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.754 rs2036857 chr4:120249240 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs11250098 0.583 rs73196860 chr8:10814133 A/G cg21775007 chr8:11205619 TDH -0.55 -5.0 -0.41 1.9e-6 Morning vs. evening chronotype; TGCT cis rs4808199 0.948 rs8108647 chr19:19427623 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.65 4.72 0.39 6.18e-6 Nonalcoholic fatty liver disease; TGCT trans rs1814175 0.867 rs7926002 chr11:49616018 A/G cg15704280 chr7:45808275 SEPT13 -0.61 -6.75 -0.52 5e-10 Height; TGCT trans rs17471911 0.708 rs11189938 chr10:100780869 C/G cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs17711722 0.522 rs6957759 chr7:65271785 A/G cg20849893 chr7:64541193 NA 0.5 5.17 0.42 9.05e-7 Calcium levels; TGCT cis rs853679 0.585 rs201001 chr6:27808899 T/C cg10876282 chr6:28092338 ZSCAN16 0.58 4.79 0.39 4.76e-6 Depression; TGCT cis rs7715806 0.500 rs10515213 chr5:74980572 C/T cg19683494 chr5:74908142 NA -0.56 -5.07 -0.41 1.43e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7000551 0.751 rs1482337 chr8:22395509 A/G cg12081754 chr8:22256438 SLC39A14 -0.28 -4.46 -0.37 1.85e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT trans rs561341 0.609 rs11658984 chr17:30186612 C/T cg20587970 chr11:113659929 NA 0.66 8.12 0.59 3.98e-13 Hip circumference adjusted for BMI; TGCT cis rs1552244 0.882 rs55840655 chr3:10042690 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs7523273 0.565 rs2104303 chr1:207886684 C/T cg22525895 chr1:207977042 MIR29B2 -0.35 -5.82 -0.46 4.72e-8 Schizophrenia; TGCT cis rs2404602 0.647 rs12903586 chr15:77168240 G/A cg23625390 chr15:77176239 SCAPER -0.39 -5.05 -0.41 1.55e-6 Blood metabolite levels; TGCT cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.501 rs7611731 chr3:52692721 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs9790314 0.540 rs35462273 chr3:160991877 C/T cg03342759 chr3:160939853 NMD3 -0.51 -5.42 -0.44 2.98e-7 Morning vs. evening chronotype; TGCT cis rs2956278 0.603 rs2947132 chr12:84691481 C/T cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs6938 0.575 rs12902515 chr15:75160998 G/C cg09165964 chr15:75287851 SCAMP5 0.53 5.08 0.42 1.33e-6 Breast cancer; TGCT cis rs35160687 0.862 rs17737955 chr2:86508014 C/T cg03171300 chr2:86307199 POLR1A 0.32 5.35 0.43 4.05e-7 Night sleep phenotypes; TGCT trans rs459571 0.959 rs2073818 chr9:136918662 C/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.79 -8.59 -0.61 3.1e-14 Platelet distribution width; TGCT trans rs7618501 0.933 rs3811695 chr3:49761613 C/T cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs2224391 0.628 rs9504365 chr6:5256116 A/G cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -6.11 -0.48 1.21e-8 Height; TGCT cis rs1008375 0.902 rs6844984 chr4:17651304 C/G cg18681998 chr4:17616180 MED28 1.02 12.01 0.73 1.65e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1691799 0.899 rs1168303 chr12:66738586 A/G cg16791601 chr12:66731901 HELB -0.28 -6.11 -0.48 1.19e-8 White blood cell count (basophil); TGCT cis rs1729951 0.575 rs361243 chr3:136697786 C/T cg21827317 chr3:136751795 NA 0.4 5.6 0.45 1.28e-7 Neuroticism; TGCT cis rs6987853 0.830 rs4361746 chr8:42355041 C/T cg20539142 chr8:42623718 CHRNA6 0.19 4.52 0.38 1.44e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs11235843 0.636 rs6592531 chr11:73412354 C/T cg18195628 chr11:73498948 MRPL48 -0.64 -4.52 -0.38 1.42e-5 Hand grip strength; TGCT cis rs6723226 0.961 rs13010404 chr2:32848854 T/G cg02381751 chr2:32503542 YIPF4 -0.52 -4.82 -0.4 4.18e-6 Intelligence (multi-trait analysis); TGCT cis rs7264396 0.635 rs6060709 chr20:34536022 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg06753367 chr22:24256600 NA -0.24 -4.66 -0.39 7.89e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2932538 0.922 rs12048528 chr1:113210534 A/C cg22162597 chr1:113214053 CAPZA1 -0.28 -6.31 -0.49 4.46e-9 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1403694 0.515 rs710448 chr3:186452885 A/G cg12454167 chr3:186435060 KNG1 0.44 6.91 0.53 2.24e-10 Blood protein levels; TGCT cis rs1062177 1.000 rs2964571 chr5:151171256 C/T cg00977110 chr5:151150581 G3BP1 0.4 4.57 0.38 1.16e-5 Preschool internalizing problems; TGCT cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT trans rs208520 0.690 rs3846808 chr6:66818604 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.98 -0.7 5.08e-20 Exhaled nitric oxide output; TGCT cis rs79149102 0.649 rs75985113 chr15:75379312 C/T cg09165964 chr15:75287851 SCAMP5 -1.02 -5.43 -0.44 2.87e-7 Lung cancer; TGCT cis rs6089829 0.925 rs11086152 chr20:61664656 T/C cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs3733585 0.699 rs6844316 chr4:9958977 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4237845 0.788 rs1962047 chr12:58292707 G/A cg23860436 chr12:58378763 NA 0.35 4.92 0.4 2.7e-6 Intelligence (multi-trait analysis); TGCT cis rs10791323 0.604 rs2853116 chr11:133707063 A/G cg15485101 chr11:133734466 NA 0.41 5.17 0.42 9.21e-7 Childhood ear infection; TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg03188948 chr7:1209495 NA 0.49 6.93 0.53 2.07e-10 Longevity;Endometriosis; TGCT cis rs916888 0.773 rs199439 chr17:44793503 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.76 5.05 0.41 1.51e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs910316 0.967 rs4899551 chr14:75660246 C/G cg08847533 chr14:75593920 NEK9 -0.94 -10.15 -0.67 5.35e-18 Height; TGCT cis rs7726839 0.540 rs72707016 chr5:665148 A/G cg09021430 chr5:549028 NA -0.4 -5.64 -0.45 1.08e-7 Obesity-related traits; TGCT cis rs7223966 1.000 rs9903903 chr17:61762044 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.05 0.41 1.51e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9814567 0.702 rs9871226 chr3:134331466 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10479542 0.752 rs12658664 chr5:178986987 C/T cg05457628 chr5:178986728 RUFY1 0.54 6.32 0.49 4.19e-9 Lung cancer; TGCT cis rs3803170 0.513 rs11065884 chr12:111818701 A/G cg10833066 chr12:111807467 FAM109A 0.35 5.51 0.44 1.94e-7 Mean corpuscular hemoglobin; TGCT cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg08219700 chr8:58056026 NA 0.39 5.06 0.41 1.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs2760061 0.569 rs621631 chr1:228114728 A/G cg02753203 chr1:228287806 NA -0.34 -6.64 -0.51 8.94e-10 Diastolic blood pressure; TGCT cis rs3749237 0.964 rs11714957 chr3:49776178 C/T cg07636037 chr3:49044803 WDR6 0.64 5.63 0.45 1.13e-7 Resting heart rate; TGCT cis rs56399783 0.901 rs73049327 chr7:2795544 T/G cg19731401 chr7:2775893 GNA12 0.35 4.92 0.4 2.7e-6 Childhood ear infection; TGCT cis rs1862618 1.000 rs1862618 chr5:56096315 C/G cg20203395 chr5:56204925 C5orf35 -0.56 -4.96 -0.41 2.31e-6 Initial pursuit acceleration; TGCT cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2019216 0.521 rs9807074 chr17:21930856 T/C cg22648282 chr17:21454238 C17orf51 -0.59 -5.89 -0.47 3.46e-8 Pelvic organ prolapse; TGCT cis rs236907 0.859 rs56377810 chr1:171757657 A/C cg20598894 chr1:171756153 METTL13 -0.2 -4.54 -0.38 1.31e-5 Mean platelet volume; TGCT cis rs7772486 0.720 rs991507 chr6:146023609 G/A cg05347473 chr6:146136440 FBXO30 -0.52 -4.85 -0.4 3.61e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9914544 0.564 rs9907723 chr17:18758853 T/C cg26378065 chr17:18585709 ZNF286B 0.53 4.59 0.38 1.09e-5 Educational attainment (years of education); TGCT cis rs9611565 0.506 rs4822020 chr22:41700203 C/T cg13695892 chr22:41940480 POLR3H -0.67 -6.2 -0.49 7.58e-9 Vitiligo; TGCT cis rs617219 0.710 rs2591386 chr5:78561373 C/T cg23514016 chr5:78407564 BHMT 0.32 4.86 0.4 3.48e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4237845 0.611 rs7298370 chr12:58318897 C/T cg02175503 chr12:58329896 NA 0.69 7.42 0.55 1.63e-11 Intelligence (multi-trait analysis); TGCT cis rs1395 0.744 rs11679220 chr2:27476378 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.65 8.48 0.61 5.54e-14 Blood metabolite levels; TGCT cis rs6570726 0.620 rs367693 chr6:145815949 G/A cg05347473 chr6:146136440 FBXO30 0.62 5.72 0.46 7.48e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2762353 0.808 rs1165179 chr6:25826514 C/T cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.63e-9 Blood metabolite levels; TGCT cis rs3820068 0.603 rs56032936 chr1:15970953 T/C cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.25e-13 Systolic blood pressure; TGCT cis rs17030434 0.627 rs17371643 chr4:154769372 C/T cg14289246 chr4:154710475 SFRP2 -0.85 -7.05 -0.54 1.07e-10 Electrocardiographic conduction measures; TGCT cis rs2769264 0.505 rs11801791 chr1:151387508 C/T cg18801370 chr1:151430492 POGZ 0.64 6.17 0.48 8.77e-9 Blood trace element (Cu levels); TGCT cis rs7829975 0.536 rs2980439 chr8:8094870 G/A cg15462221 chr8:8086144 FLJ10661 -0.53 -4.89 -0.4 3.11e-6 Mood instability; TGCT cis rs612683 0.599 rs2809823 chr1:101003762 C/A cg10298815 chr1:101004474 GPR88 0.25 4.74 0.39 5.67e-6 Breast cancer; TGCT cis rs6430585 0.527 rs12465544 chr2:136451676 C/T cg07169764 chr2:136633963 MCM6 1.0 9.14 0.63 1.51e-15 Corneal structure; TGCT cis rs2735413 0.564 rs73580867 chr16:78120953 C/T cg09132178 chr16:78079569 NA 0.35 4.51 0.38 1.47e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs11264213 0.901 rs682686 chr1:36443778 T/A cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs10791097 0.609 rs3751039 chr11:130773076 A/G cg14779329 chr11:130786720 SNX19 -0.28 -4.8 -0.4 4.55e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9467711 0.790 rs67777156 chr6:26633711 T/A cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2455799 0.613 rs11920540 chr3:15854608 G/A cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.19e-6 Mean platelet volume; TGCT cis rs9916302 0.904 rs801426 chr17:37441109 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.05 0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs7000551 0.715 rs34649162 chr8:22314730 T/C cg12081754 chr8:22256438 SLC39A14 0.3 5.04 0.41 1.59e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs13191362 0.935 rs66923841 chr6:163177317 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.94 6.76 0.52 4.71e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs921968 0.607 rs529474 chr2:219463283 C/T cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs826838 1.000 rs11609286 chr12:38875511 A/G cg26384229 chr12:38710491 ALG10B -1.06 -10.68 -0.69 2.84e-19 Heart rate; TGCT cis rs2075371 0.501 rs1646653 chr7:134024686 A/G cg11752832 chr7:134001865 SLC35B4 0.61 5.18 0.42 8.64e-7 Mean platelet volume; TGCT cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg23172400 chr8:95962367 TP53INP1 0.36 6.04 0.48 1.7e-8 Type 2 diabetes; TGCT cis rs2456568 0.900 rs877340 chr11:93689292 A/T cg26875233 chr11:93583750 C11orf90 -0.45 -5.65 -0.45 1.03e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs208520 0.779 rs208451 chr6:66906155 G/A cg07460842 chr6:66804631 NA -0.9 -9.14 -0.63 1.54e-15 Exhaled nitric oxide output; TGCT cis rs9911578 1.000 rs8076121 chr17:57041699 G/A cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs514406 0.861 rs503015 chr1:53254456 T/C cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs9527 0.545 rs10883847 chr10:104958284 C/T cg04362960 chr10:104952993 NT5C2 0.68 5.73 0.46 7.14e-8 Arsenic metabolism; TGCT cis rs2836974 0.931 rs2776307 chr21:40713833 C/G cg11644478 chr21:40555479 PSMG1 -0.86 -8.29 -0.6 1.54e-13 Cognitive function; TGCT trans rs208520 0.690 rs2144081 chr6:66824972 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.72 -0.69 2.28e-19 Exhaled nitric oxide output; TGCT cis rs7542091 0.635 rs985431 chr1:210043948 A/T cg21951975 chr1:209979733 IRF6 0.6 6.1 0.48 1.24e-8 Monobrow; TGCT cis rs2243480 1.000 rs160633 chr7:65528228 T/C cg18252515 chr7:66147081 NA -1.13 -7.39 -0.55 1.94e-11 Diabetic kidney disease; TGCT trans rs7618501 1.000 rs6775384 chr3:49853073 G/A cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.7e-25 Intelligence (multi-trait analysis); TGCT cis rs7119038 0.774 rs10892290 chr11:118653503 G/T cg19308663 chr11:118741387 NA 0.31 6.13 0.48 1.06e-8 Sjögren's syndrome; TGCT cis rs78487399 0.808 rs7586101 chr2:43669851 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.43 5.45 0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg21016266 chr12:122356598 WDR66 0.5 7.11 0.54 7.97e-11 Mean corpuscular volume; TGCT cis rs3749237 0.964 rs34522271 chr3:49808517 A/G cg10152585 chr3:50297680 NA 0.5 4.59 0.38 1.08e-5 Resting heart rate; TGCT cis rs2842992 0.830 rs1998365 chr6:160179535 A/T cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs9993613 0.841 rs6852061 chr4:73436699 G/A cg15102770 chr4:73434591 ADAMTS3 0.53 4.82 0.4 4.11e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs7666738 0.830 rs7657497 chr4:99044028 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs10049627 chr4:99025272 A/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs769267 1.000 rs7247309 chr19:19439631 A/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs7752195 0.643 rs76426173 chr6:25317752 T/C cg16898833 chr6:26189333 HIST1H4D 1.2 5.18 0.42 8.53e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7698623 0.850 rs4693883 chr4:88770174 A/G cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs2486288 0.656 rs9921025 chr15:45546602 G/A cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs11031096 0.589 rs935130 chr11:4213530 A/G cg18678763 chr11:4115507 RRM1 -0.43 -5.54 -0.45 1.77e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2188554 0.785 rs2518881 chr7:117172731 A/G cg08576598 chr7:116962626 WNT2 -0.36 -4.71 -0.39 6.55e-6 Esophageal adenocarcinoma; TGCT cis rs10504229 1.000 rs116444534 chr8:58181915 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2549003 1.000 rs10068129 chr5:131821246 A/G cg21138405 chr5:131827807 IRF1 -0.18 -4.69 -0.39 7.03e-6 Asthma (sex interaction); TGCT cis rs2839186 0.609 rs2839189 chr21:47694357 C/T cg09417038 chr21:47716443 C21orf57 0.33 5.03 0.41 1.67e-6 Testicular germ cell tumor; TGCT cis rs9787249 0.874 rs12094291 chr1:40226046 G/A cg20968010 chr1:40505947 CAP1 -0.5 -4.68 -0.39 7.29e-6 Blood protein levels; TGCT cis rs7095607 0.606 rs7095492 chr10:69957375 C/T cg18986048 chr10:69913749 MYPN 0.56 5.87 0.47 3.76e-8 Lung function (FVC); TGCT cis rs3749237 0.557 rs7631908 chr3:49425707 T/G cg07636037 chr3:49044803 WDR6 0.64 6.04 0.48 1.63e-8 Resting heart rate; TGCT cis rs10504229 1.000 rs115548028 chr8:58170672 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs10751667 0.643 rs10794350 chr11:946070 A/G cg06064525 chr11:970664 AP2A2 -0.34 -7.95 -0.58 9.9e-13 Alzheimer's disease (late onset); TGCT cis rs6540559 0.673 rs17015183 chr1:209948711 A/C cg23283495 chr1:209979779 IRF6 0.67 5.23 0.43 6.85e-7 Cleft lip with or without cleft palate; TGCT cis rs617219 0.684 rs2896766 chr5:78586493 A/G cg05890484 chr5:78407552 BHMT -0.34 -4.63 -0.38 8.97e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6426558 0.681 rs10495274 chr1:227175253 C/T cg10327440 chr1:227177885 CDC42BPA -0.69 -7.85 -0.58 1.72e-12 Neutrophil percentage of white cells; TGCT cis rs7829975 0.606 rs7819827 chr8:8797055 G/C cg06636001 chr8:8085503 FLJ10661 -0.7 -6.19 -0.49 8.23e-9 Mood instability; TGCT cis rs12643440 0.530 rs551555 chr4:17231715 C/G cg23316648 chr4:17096664 NA -0.24 -4.47 -0.37 1.73e-5 Metabolite levels (Pyroglutamine); TGCT cis rs9303401 0.615 rs35288118 chr17:56600748 A/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs68092024 0.731 rs793479 chr3:99488232 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 5.94 0.47 2.64e-8 Cleft lip with or without cleft palate; TGCT cis rs6429082 0.818 rs210037 chr1:235649501 A/G cg26050004 chr1:235667680 B3GALNT2 0.59 5.26 0.43 6.02e-7 Adiposity; TGCT cis rs10858047 0.883 rs4543788 chr1:115179501 C/T cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs854765 0.587 rs4077828 chr17:17833644 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs9916302 0.653 rs11657058 chr17:37699378 T/G cg07936489 chr17:37558343 FBXL20 -0.84 -6.16 -0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1372520 0.564 rs2737011 chr4:90746219 T/C cg01966878 chr4:90757139 SNCA -0.3 -4.64 -0.38 8.54e-6 Neuroticism; TGCT cis rs78487399 0.520 rs7609256 chr2:43672499 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.09 -0.42 1.3e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7267979 0.706 rs6138542 chr20:25207773 C/A cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.54e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs873946 0.689 rs2803993 chr10:134550606 T/C cg18305652 chr10:134549665 INPP5A 0.31 4.91 0.4 2.83e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs36207871 1 rs36207871 chr12:56684496 TAGGAA/T cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Inflammatory skin disease; TGCT cis rs524281 0.861 rs11227411 chr11:65879478 C/T cg00563793 chr11:65837595 PACS1 0.55 4.62 0.38 9.28e-6 Electroencephalogram traits; TGCT cis rs1891275 0.515 rs1418161 chr10:93484655 C/G cg07889827 chr10:93443413 NA -0.32 -6.74 -0.52 5.19e-10 Intelligence (multi-trait analysis); TGCT trans rs6089829 0.889 rs6062773 chr20:61663262 G/C cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs2997447 0.633 rs6665062 chr1:26362001 C/T cg19633962 chr1:26362018 EXTL1 -0.7 -4.72 -0.39 6.3e-6 QRS complex (12-leadsum); TGCT cis rs13223928 0.541 rs17132968 chr7:3136074 T/G cg19214707 chr7:3157722 NA -0.43 -5.77 -0.46 5.93e-8 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs1862618 0.853 rs832553 chr5:56114786 A/G cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs16854884 0.789 rs34096668 chr3:143794483 C/T cg06585982 chr3:143692056 C3orf58 0.62 4.82 0.4 4.11e-6 Economic and political preferences (feminism/equality); TGCT cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6912958 0.781 rs4464759 chr6:88282621 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs76878669 0.561 rs56321771 chr11:66161072 C/T cg18002602 chr11:66138449 SLC29A2 0.53 6.57 0.51 1.22e-9 Educational attainment (years of education); TGCT cis rs3858526 0.959 rs1840179 chr11:5949148 A/G cg13902645 chr11:5959945 NA -0.48 -5.0 -0.41 1.95e-6 DNA methylation (variation); TGCT cis rs666930 0.519 rs483180 chr1:120267505 C/G cg19096424 chr1:120255104 PHGDH -0.64 -5.66 -0.45 1.01e-7 Breast cancer; TGCT cis rs6089584 0.606 rs7270469 chr20:60577258 G/A cg06108461 chr20:60628389 TAF4 -0.4 -5.02 -0.41 1.74e-6 Body mass index; TGCT cis rs55962025 0.883 rs362273 chr4:3227419 A/G cg06533319 chr4:3265114 C4orf44 0.24 4.63 0.38 9.13e-6 Parental longevity (mother's age at death); TGCT cis rs240764 0.853 rs12660725 chr6:100978570 C/T cg21058520 chr6:100914733 NA 0.35 4.63 0.38 9.07e-6 Neuroticism; TGCT cis rs12776158 0.901 rs12414706 chr10:71214729 G/A cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs881375 0.900 rs1930786 chr9:123691469 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.99 0.41 2.03e-6 Rheumatoid arthritis; TGCT cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg03264133 chr6:25882463 NA -0.73 -6.94 -0.53 1.97e-10 Intelligence (multi-trait analysis); TGCT cis rs12188164 0.965 rs72717438 chr5:448663 C/T cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs72945132 0.660 rs67433166 chr11:70121604 T/A cg00319359 chr11:70116639 PPFIA1 0.99 7.24 0.55 4.12e-11 Coronary artery disease; TGCT trans rs77457752 0.690 rs12349396 chr9:13912144 T/C cg12973904 chr7:149457885 NA 0.46 7.07 0.54 9.92e-11 Breast cancer; TGCT cis rs3138083 0.645 rs12376747 chr9:35639629 C/G cg07116010 chr9:35646325 NA 0.82 10.29 0.68 2.44e-18 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel); TGCT cis rs1975974 1.000 rs111981054 chr17:21725592 C/G cg18423549 chr17:21743878 NA -0.55 -5.06 -0.41 1.49e-6 Psoriasis; TGCT cis rs2742417 0.935 rs2742442 chr3:45748599 T/A cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT trans rs3780486 0.957 rs10971434 chr9:33168891 C/A cg20290983 chr6:43655470 MRPS18A 1.13 10.89 0.7 8.6e-20 IgG glycosylation; TGCT cis rs1862618 0.671 rs72644088 chr5:56241019 G/A cg24531977 chr5:56204891 C5orf35 0.7 7.39 0.55 1.91e-11 Initial pursuit acceleration; TGCT cis rs2346177 1.000 rs2346177 chr2:46642249 A/G cg26688816 chr2:46740690 ATP6V1E2 0.41 4.5 0.37 1.54e-5 HDL cholesterol; TGCT cis rs1005224 0.895 rs11624114 chr14:76131800 A/G cg04684003 chr14:76127793 TTLL5;C14orf1 -0.6 -5.67 -0.45 9.59e-8 Large artery stroke; TGCT cis rs28386778 0.897 rs1470697 chr17:61799840 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.97 -0.41 2.18e-6 Prudent dietary pattern; TGCT cis rs425277 0.538 rs169037 chr1:2095582 G/T cg03732007 chr1:2071316 PRKCZ 0.28 6.63 0.51 9.05e-10 Height; TGCT cis rs79349575 0.715 rs4793997 chr17:47019672 C/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs739496 0.615 rs4648328 chr12:112222788 C/T cg10833066 chr12:111807467 FAM109A 0.36 4.67 0.39 7.74e-6 Platelet count; TGCT cis rs3806843 0.741 rs4912597 chr5:140106857 C/G cg19875535 chr5:140030758 IK -0.37 -6.19 -0.49 7.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9291683 0.609 rs12500810 chr4:10031068 G/A cg00071950 chr4:10020882 SLC2A9 0.67 8.64 0.61 2.31e-14 Bone mineral density; TGCT cis rs1008375 1.000 rs7671752 chr4:17661398 C/T cg16339924 chr4:17578868 LAP3 0.58 4.96 0.41 2.29e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2016266 0.855 rs1056692 chr12:53687387 A/G cg16917193 chr12:54089295 NA -0.71 -5.18 -0.42 8.57e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs116095464 0.614 rs62344339 chr5:252995 T/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs10972341 1.000 rs4879869 chr9:35141508 C/T cg00812861 chr9:35114699 KIAA1539 0.34 5.06 0.41 1.47e-6 Weight; TGCT cis rs28374715 0.532 rs7168431 chr15:41672384 A/G cg18705301 chr15:41695430 NDUFAF1 -0.93 -16.21 -0.82 2.08e-32 Ulcerative colitis; TGCT cis rs7091068 0.671 rs1096025 chr10:95404701 T/C cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs7267979 1.000 rs2258135 chr20:25272323 C/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7216064 0.765 rs6504550 chr17:65894542 A/G cg12091567 chr17:66097778 LOC651250 -0.76 -5.79 -0.46 5.42e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4824093 0.610 rs73441745 chr22:50237606 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.45 4.64 0.38 8.83e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1552244 0.935 rs7618815 chr3:10151045 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs13191362 1.000 rs67747005 chr6:163150845 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.69 5.81 0.46 4.87e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs651907 0.557 rs17411983 chr3:101399126 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 -0.55 -5.03 -0.41 1.65e-6 Colorectal cancer; TGCT cis rs270601 0.770 rs932019 chr5:131599370 T/C cg24060327 chr5:131705240 SLC22A5 -0.66 -6.87 -0.53 2.75e-10 Acylcarnitine levels; TGCT cis rs9814567 0.752 rs4306899 chr3:134334513 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.75 6.75 0.52 4.98e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9581857 0.547 rs78273785 chr13:28052884 T/C cg22138327 chr13:27999177 GTF3A 0.74 4.82 0.4 4.15e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs10037670 0.608 rs73285282 chr5:153821966 G/C cg21964928 chr5:153872958 NA 0.26 4.59 0.38 1.09e-5 Behavioural disinhibition (generation interaction); TGCT cis rs6840360 0.967 rs7667197 chr4:152613952 G/A cg22705602 chr4:152727874 NA -0.25 -4.47 -0.37 1.71e-5 Intelligence (multi-trait analysis); TGCT cis rs10779751 0.887 rs6686835 chr1:11305316 G/A cg08854313 chr1:11322531 MTOR 0.99 10.58 0.69 4.78e-19 Body mass index; TGCT cis rs476633 0.708 rs13329237 chr15:41450808 A/C cg18705301 chr15:41695430 NDUFAF1 -0.59 -7.88 -0.58 1.42e-12 Glomerular filtration rate (creatinine); TGCT cis rs6987853 0.830 rs2272685 chr8:42354102 C/T cg20539142 chr8:42623718 CHRNA6 0.19 4.52 0.38 1.44e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs11785400 0.793 rs4430070 chr8:143729184 G/C cg10596483 chr8:143751796 JRK 0.53 5.21 0.42 7.5e-7 Schizophrenia; TGCT cis rs3091242 1.000 rs646867 chr1:25709258 A/C cg23205692 chr1:25664452 TMEM50A 0.51 5.23 0.42 7.13e-7 Erythrocyte sedimentation rate; TGCT cis rs6733011 0.578 rs10181972 chr2:99497284 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.76 -0.39 5.3e-6 Bipolar disorder; TGCT cis rs12950390 0.853 rs56363619 chr17:45854621 T/C cg24803719 chr17:45855879 NA -0.47 -4.76 -0.39 5.24e-6 IgG glycosylation; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg04234412 chr22:24373322 LOC391322 -0.94 -11.83 -0.73 4.5e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2242116 0.796 rs7623898 chr3:46974172 C/T cg23352942 chr3:46931381 PTH1R 0.31 4.44 0.37 1.94e-5 Birth weight; TGCT cis rs12497850 0.931 rs7616815 chr3:48779715 C/T cg07636037 chr3:49044803 WDR6 0.95 10.8 0.7 1.46e-19 Parkinson's disease; TGCT cis rs1018836 0.828 rs7006279 chr8:91605364 A/G cg16814680 chr8:91681699 NA -0.71 -7.25 -0.55 3.89e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg02953382 chr22:24373134 LOC391322 -0.77 -7.9 -0.58 1.27e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2469997 0.925 rs2447170 chr8:120361421 C/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs5750830 0.621 rs743838 chr22:39824707 T/G cg02038168 chr22:39784481 NA -0.79 -6.79 -0.52 4.07e-10 Intelligence (multi-trait analysis); TGCT cis rs9611565 1.000 rs1109151 chr22:41752944 A/G cg06481639 chr22:41940642 POLR3H -0.57 -5.07 -0.41 1.4e-6 Vitiligo; TGCT cis rs727505 0.607 rs10464674 chr7:124791551 A/G cg23710748 chr7:124431027 NA -0.26 -4.51 -0.38 1.47e-5 Lewy body disease; TGCT cis rs7086627 0.515 rs12245180 chr10:82211897 C/G cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs6671200 0.607 rs6671408 chr1:95697091 T/C cg03123541 chr1:95699097 RWDD3 -0.8 -7.03 -0.53 1.24e-10 Stearic acid (18:0) levels; TGCT cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg00431813 chr7:1051703 C7orf50 -0.21 -4.47 -0.37 1.76e-5 Longevity;Endometriosis; TGCT cis rs9318086 0.776 rs1326130 chr13:24447664 A/C cg25267304 chr13:24462978 PCOTH;MIPEP 0.62 6.16 0.48 9.35e-9 Myopia (pathological); TGCT cis rs7072216 0.727 rs7913541 chr10:100172479 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg12311346 chr5:56204834 C5orf35 -0.63 -6.36 -0.5 3.5e-9 Initial pursuit acceleration; TGCT cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg05896524 chr21:47604654 C21orf56 -0.43 -4.54 -0.38 1.31e-5 Testicular germ cell tumor; TGCT cis rs28595532 0.702 rs72670256 chr4:119391043 G/A cg11846333 chr4:119757529 SEC24D 0.69 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.6e-9 Gut microbiome composition (summer); TGCT cis rs67072384 1.000 rs5008485 chr11:72455152 C/T cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs4786125 0.665 rs1492371 chr16:6921285 A/C cg03623568 chr16:6915990 A2BP1 -0.45 -6.77 -0.52 4.65e-10 Heart rate variability traits (SDNN); TGCT cis rs6460942 0.915 rs6966791 chr7:12439714 T/C cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs9972944 0.729 rs10512505 chr17:63776696 A/G cg07283582 chr17:63770753 CCDC46 0.27 5.19 0.42 8.35e-7 Total body bone mineral density; TGCT cis rs1005277 0.589 rs2749624 chr10:38529865 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2797160 0.602 rs4897150 chr6:125985540 C/T cg05901451 chr6:126070800 HEY2 -0.84 -7.89 -0.58 1.33e-12 Endometrial cancer; TGCT cis rs9381040 0.701 rs722442 chr6:41089681 A/G cg03526776 chr6:41159608 TREML2 0.24 4.95 0.41 2.33e-6 Alzheimer's disease (late onset); TGCT cis rs4319547 0.656 rs7135419 chr12:122911861 T/A cg08088222 chr12:122070432 ORAI1 0.26 4.53 0.38 1.34e-5 Body mass index; TGCT cis rs3749237 0.595 rs11720264 chr3:49580347 C/T cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs2204008 0.774 rs7304438 chr12:38361146 T/G cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.44e-11 Bladder cancer; TGCT cis rs11190604 1.000 rs7090431 chr10:102261753 A/G cg16342193 chr10:102329863 NA -0.39 -5.01 -0.41 1.83e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2762353 0.574 rs11756503 chr6:25710432 C/T cg15691649 chr6:25882328 NA 0.5 6.02 0.48 1.84e-8 Blood metabolite levels; TGCT cis rs7226408 0.842 rs56239982 chr18:34331754 T/A cg06757138 chr18:34340585 FHOD3 0.29 4.95 0.41 2.4e-6 Obesity-related traits; TGCT cis rs735396 0.770 rs1169301 chr12:121431300 C/T cg02403541 chr12:121454288 C12orf43 0.73 6.51 0.5 1.68e-9 N-glycan levels; TGCT cis rs9902453 1.000 rs7212497 chr17:28335949 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs2692947 0.832 rs2579550 chr2:96741944 G/A cg23100626 chr2:96804247 ASTL 0.4 4.75 0.39 5.55e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs12579753 1.000 rs66646148 chr12:82248520 T/G cg07988820 chr12:82153109 PPFIA2 -0.6 -6.61 -0.51 1.02e-9 Resting heart rate; TGCT cis rs9905704 0.647 rs9901655 chr17:56987142 G/A cg12560992 chr17:57184187 TRIM37 0.58 4.93 0.4 2.57e-6 Testicular germ cell tumor; TGCT cis rs6882046 0.513 rs185291 chr5:88006764 T/C cg22951263 chr5:87985283 NA -0.58 -6.22 -0.49 6.92e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs4268898 0.722 rs4665253 chr2:24382546 G/A cg02683114 chr2:24398427 C2orf84 0.19 4.57 0.38 1.14e-5 Asthma; TGCT cis rs7017914 0.935 rs7826483 chr8:71702893 T/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.52 -4.8 -0.4 4.53e-6 Bone mineral density; TGCT cis rs704 0.605 rs2227736 chr17:26693231 G/C cg10342447 chr17:26645325 TMEM97 -0.6 -6.02 -0.48 1.8e-8 Osteoprotegerin levels; TGCT cis rs644799 1.000 rs644799 chr11:95564259 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.9 9.97 0.67 1.46e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2243480 1.000 rs709607 chr7:65449541 C/G cg20637647 chr7:64974828 NA -1.03 -5.75 -0.46 6.45e-8 Diabetic kidney disease; TGCT cis rs1218582 0.774 rs1007170 chr1:154881461 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.65 -6.51 -0.5 1.68e-9 Prostate cancer; TGCT cis rs7474896 0.609 rs1830612 chr10:37999883 A/G cg13720705 chr10:37990370 NA 0.33 4.91 0.4 2.86e-6 Obesity (extreme); TGCT cis rs7086627 0.515 rs2125040 chr10:82208422 G/C cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs1008375 1.000 rs7697889 chr4:17617961 G/T cg18681998 chr4:17616180 MED28 1.01 11.57 0.72 1.95e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4149178 0.722 rs10948072 chr6:43307861 G/A cg12269535 chr6:43142014 SRF 0.56 4.7 0.39 6.76e-6 Urate levels; TGCT cis rs1008375 0.898 rs9998130 chr4:17593905 A/G cg10189774 chr4:17578691 LAP3 0.64 5.41 0.44 3.1e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs1580019 0.562 rs4720064 chr7:32559638 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.23 0.79 7.81e-28 Cognitive ability; TGCT cis rs9322193 0.923 rs17745062 chr6:150042215 T/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs698813 0.604 rs12712917 chr2:44482190 A/G cg00619915 chr2:44497795 NA -0.24 -5.68 -0.45 9.26e-8 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs8051431 0.840 rs8047837 chr16:72010728 G/A cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT trans rs7618501 0.521 rs34654589 chr3:49911449 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.82 8.47 0.61 6.11e-14 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg02487422 chr3:49467188 NICN1 0.55 5.32 0.43 4.77e-7 Menarche (age at onset); TGCT cis rs11190604 0.943 rs7085261 chr10:102209811 G/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2243480 0.908 rs55876148 chr7:65379800 G/A cg07424592 chr7:64974309 NA 1.36 8.08 0.59 4.97e-13 Diabetic kidney disease; TGCT cis rs7584330 0.554 rs74001383 chr2:238424418 T/C cg08992911 chr2:238395768 MLPH 0.73 5.01 0.41 1.85e-6 Prostate cancer; TGCT cis rs6138458 1.000 rs227615 chr20:24908721 T/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs75059851 0.756 rs11223659 chr11:133844708 G/A cg14047540 chr11:133829660 NA -0.58 -5.77 -0.46 6.07e-8 Schizophrenia; TGCT cis rs12200560 0.505 rs984520 chr6:97076454 A/G cg06623918 chr6:96969491 KIAA0776 -0.61 -5.25 -0.43 6.53e-7 Coronary heart disease; TGCT cis rs4148883 0.675 rs10000357 chr4:100099942 G/C cg12011299 chr4:100065546 ADH4 0.39 5.85 0.47 4.03e-8 Alcohol dependence; TGCT cis rs7208859 0.623 rs11657990 chr17:29124200 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9549367 0.789 rs9549361 chr13:113898329 C/T cg18105134 chr13:113819100 PROZ 0.34 5.51 0.44 1.96e-7 Platelet distribution width; TGCT cis rs3902035 0.964 rs1891715 chr6:119004731 A/G cg07617317 chr6:118971624 C6orf204 -0.43 -5.08 -0.41 1.37e-6 QT interval; TGCT cis rs7937682 0.737 rs663763 chr11:111422217 C/T cg09085632 chr11:111637200 PPP2R1B -0.8 -8.33 -0.6 1.3e-13 Primary sclerosing cholangitis; TGCT cis rs698833 0.506 rs4952705 chr2:44499867 T/C cg00619915 chr2:44497795 NA -0.22 -4.99 -0.41 2.02e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs9393692 0.875 rs6939589 chr6:26289203 C/T cg00631329 chr6:26305371 NA 0.44 6.48 0.5 1.95e-9 Educational attainment; TGCT cis rs9611565 0.512 rs715498 chr22:42148467 G/A cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs9952991 0.941 rs2542150 chr18:12779763 G/C cg09945482 chr18:12777974 NA 0.51 4.86 0.4 3.47e-6 Inflammatory skin disease; TGCT cis rs651907 0.514 rs10936744 chr3:101433440 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.89 10.45 0.68 1.02e-18 Colorectal cancer; TGCT cis rs3749237 1.000 rs2291542 chr3:49751585 C/T cg07636037 chr3:49044803 WDR6 0.64 5.55 0.45 1.68e-7 Resting heart rate; TGCT cis rs6840360 0.533 rs13147021 chr4:152722688 A/C cg22705602 chr4:152727874 NA 0.33 6.0 0.47 2.01e-8 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.867 rs7726582 chr5:215349 C/G cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs13064411 0.627 rs28710051 chr3:113143531 G/A cg10517650 chr3:113235015 CCDC52 -0.35 -4.63 -0.38 9.06e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs614226 0.935 rs3887875 chr12:120895749 A/G cg01236616 chr12:121019343 POP5 -1.23 -12.24 -0.74 4.57e-23 Type 1 diabetes nephropathy; TGCT cis rs3806843 0.547 rs246048 chr5:140327900 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs11031096 0.782 rs10767845 chr11:4156922 C/T cg18678763 chr11:4115507 RRM1 -0.52 -6.66 -0.51 7.83e-10 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1552244 0.554 rs13079240 chr3:10047246 C/T cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs61990749 0.597 rs1477260 chr14:78256818 G/C cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs4862750 0.837 rs1863404 chr4:187874654 T/C cg10295955 chr4:187884368 NA -0.98 -14.77 -0.8 4.24e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs12615966 0.789 rs6758786 chr2:105367587 A/G cg16465502 chr2:105461796 NA -0.75 -4.7 -0.39 6.76e-6 Pancreatic cancer; TGCT cis rs7954584 0.531 rs11043271 chr12:122394921 A/C cg22168489 chr12:122356033 WDR66 0.22 4.76 0.39 5.3e-6 Mean corpuscular volume; TGCT cis rs3008870 1.000 rs2815352 chr1:67482104 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.08 11.47 0.72 3.32e-21 Lymphocyte percentage of white cells; TGCT cis rs9916302 0.904 rs8077104 chr17:37530510 A/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT trans rs1005277 0.505 rs7069702 chr10:38247359 G/T cg17830980 chr10:43048298 ZNF37B 0.73 8.35 0.6 1.13e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2404602 0.735 rs2454450 chr15:76831236 G/A cg22467129 chr15:76604101 ETFA 0.44 4.56 0.38 1.22e-5 Blood metabolite levels; TGCT cis rs4819052 0.851 rs2838865 chr21:46712299 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7312933 0.558 rs11181502 chr12:42823833 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.14 0.42 1.06e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6546537 0.562 rs1985342 chr2:69758927 C/T cg10773587 chr2:69614142 GFPT1 -0.87 -9.17 -0.64 1.31e-15 Serum thyroid-stimulating hormone levels; TGCT cis rs10193935 0.901 rs6724626 chr2:42689757 C/G cg27598129 chr2:42591480 NA 0.39 5.39 0.44 3.39e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.738 rs4402703 chr2:238374957 T/A cg14458575 chr2:238380390 NA 0.48 7.62 0.56 5.63e-12 Prostate cancer; TGCT cis rs9818758 0.607 rs3923475 chr3:49055788 G/T cg00383909 chr3:49044727 WDR6 1.3 6.73 0.52 5.74e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT trans rs4650994 0.816 rs2811304 chr1:178596794 A/T cg05059571 chr16:84539110 KIAA1609 0.4 7.53 0.56 8.98e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6933660 0.646 rs9397410 chr6:151770503 C/T cg14262678 chr6:151773367 RMND1;C6orf211 0.56 5.53 0.44 1.83e-7 Menarche (age at onset); TGCT cis rs9549367 0.713 rs56002882 chr13:113830694 T/C cg00898013 chr13:113819073 PROZ -0.55 -7.05 -0.53 1.12e-10 Platelet distribution width; TGCT cis rs4555082 0.834 rs11622165 chr14:105759761 C/A cg01266790 chr14:105781312 PACS2 0.56 4.64 0.38 8.89e-6 Mean platelet volume;Platelet distribution width; TGCT cis rs7617773 0.743 rs71323397 chr3:48374874 A/G cg11946769 chr3:48343235 NME6 0.81 6.96 0.53 1.71e-10 Coronary artery disease; TGCT cis rs9611565 0.694 rs9607816 chr22:41950897 G/A cg13695892 chr22:41940480 POLR3H -0.91 -9.11 -0.63 1.82e-15 Vitiligo; TGCT cis rs4455778 0.538 rs4326333 chr7:49125565 A/T cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs7959452 0.503 rs7300266 chr12:69654187 A/G cg14784868 chr12:69753453 YEATS4 0.69 7.13 0.54 7.26e-11 Blood protein levels; TGCT cis rs10791097 0.568 rs4411284 chr11:130738568 A/C cg05962950 chr11:130786565 SNX19 0.91 11.51 0.72 2.63e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7246657 0.722 rs2972447 chr19:38129736 C/T cg03611452 chr19:38183253 ZNF781 -0.59 -4.76 -0.39 5.34e-6 Coronary artery calcification; TGCT cis rs7845219 0.544 rs2945554 chr8:95939594 C/A cg16049864 chr8:95962084 TP53INP1 -0.49 -5.42 -0.44 2.98e-7 Type 2 diabetes; TGCT cis rs74233809 1.000 rs943037 chr10:104835919 C/T cg05855489 chr10:104503620 C10orf26 0.82 4.58 0.38 1.12e-5 Birth weight; TGCT cis rs9913156 0.793 rs55974786 chr17:4567564 T/C cg23387401 chr17:4582204 PELP1 0.31 4.59 0.38 1.09e-5 Lymphocyte counts; TGCT cis rs9534288 0.762 rs9534285 chr13:46601902 T/C cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs7647973 0.626 rs9835157 chr3:49797769 G/A cg03060546 chr3:49711283 APEH -0.63 -5.63 -0.45 1.12e-7 Menarche (age at onset); TGCT cis rs10751667 0.643 rs10902245 chr11:953014 C/T cg06064525 chr11:970664 AP2A2 0.35 8.01 0.58 7.17e-13 Alzheimer's disease (late onset); TGCT cis rs13067306 1.000 rs13067306 chr3:94243713 C/T cg16274205 chr3:94243571 NA 0.42 4.86 0.4 3.48e-6 Blood pressure measurement (high sodium intervention); TGCT cis rs1018836 0.923 rs2105965 chr8:91537690 T/C cg16814680 chr8:91681699 NA -0.88 -9.89 -0.66 2.34e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9916302 0.851 rs7220650 chr17:37487168 A/G cg07936489 chr17:37558343 FBXL20 0.65 5.05 0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.683 rs55645894 chr8:58116145 A/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg02187348 chr16:89574699 SPG7 0.62 6.86 0.52 2.85e-10 Multiple myeloma (IgH translocation); TGCT cis rs151997 0.962 rs27272 chr5:50181865 A/G cg06027927 chr5:50259733 NA 0.46 4.61 0.38 9.69e-6 Callous-unemotional behaviour; TGCT cis rs10791097 0.967 rs10791099 chr11:130718813 G/C cg12179176 chr11:130786555 SNX19 0.65 6.88 0.53 2.63e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2839186 0.770 rs2330353 chr21:47669648 T/A cg13732083 chr21:47605072 C21orf56 0.34 4.52 0.38 1.44e-5 Testicular germ cell tumor; TGCT cis rs6088590 0.561 rs11167239 chr20:33140472 G/A cg06115741 chr20:33292138 TP53INP2 0.54 4.72 0.39 6.29e-6 Coronary artery disease; TGCT cis rs7412746 0.611 rs11803940 chr1:150685835 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Melanoma; TGCT cis rs6076065 0.722 rs6048760 chr20:23345844 G/T cg11657817 chr20:23433608 CST11 -0.32 -5.39 -0.44 3.49e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs7208859 0.673 rs9891179 chr17:29208160 G/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg09222892 chr1:25734099 RHCE 0.42 6.88 0.53 2.61e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs7568458 0.663 rs699664 chr2:85780536 A/G cg17127132 chr2:85788382 GGCX -0.5 -4.83 -0.4 3.89e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4242434 0.689 rs4872006 chr8:22536502 T/C cg03733263 chr8:22462867 KIAA1967 -1.08 -15.57 -0.81 5.71e-31 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7666738 0.791 rs2903151 chr4:99027218 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.738 rs72918577 chr4:120326701 G/A cg09307838 chr4:120376055 NA 0.7 6.7 0.52 6.57e-10 Corneal astigmatism; TGCT cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg06481639 chr22:41940642 POLR3H -0.69 -6.15 -0.48 9.84e-9 Vitiligo; TGCT cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg23205692 chr1:25664452 TMEM50A 0.53 5.46 0.44 2.5e-7 Erythrocyte sedimentation rate; TGCT cis rs6740322 0.696 rs11685054 chr2:43474295 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.15 -0.48 9.74e-9 Coronary artery disease; TGCT cis rs17152411 0.895 rs61872119 chr10:126583534 A/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs875971 0.505 rs6955582 chr7:65431686 A/G cg18876405 chr7:65276391 NA 0.36 5.69 0.46 8.66e-8 Aortic root size; TGCT cis rs7945705 0.967 rs7123861 chr11:8892323 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.86 0.4 3.42e-6 Hemoglobin concentration; TGCT cis rs4563143 0.514 rs73029081 chr19:29295583 C/G cg14983838 chr19:29218262 NA 0.71 5.19 0.42 8.21e-7 Methadone dose in opioid dependence; TGCT cis rs7528419 1.000 rs7528419 chr1:109817192 A/G cg00908766 chr1:109817496 CELSR2 -0.53 -5.43 -0.44 2.86e-7 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Myocardial infarction;Lipoprotein-associated phospholipase A2 activity and mass;Lipoprotein-associated phospholipase A2 activity change in response to darapladib treatment in cardiovascular disease;Cholesterol, total;Coronary artery disease; TGCT cis rs7402982 0.625 rs4966009 chr15:99203496 C/T cg03437748 chr15:99193247 IGF1R 0.45 4.45 0.37 1.86e-5 Birth weight; TGCT cis rs9368481 1.000 rs9368481 chr6:26961761 C/T cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.36 -4.58 -0.38 1.11e-5 Autism spectrum disorder or schizophrenia; TGCT trans rs57221529 0.766 rs72703065 chr5:588123 C/A cg11887960 chr12:57824829 NA 1.14 9.3 0.64 6.29e-16 Lung disease severity in cystic fibrosis; TGCT cis rs12478296 0.901 rs73007142 chr2:243010852 T/C cg06360820 chr2:242988706 NA -0.86 -5.89 -0.47 3.44e-8 Obesity-related traits; TGCT cis rs12549902 0.800 rs7825494 chr8:41507350 C/T cg21772509 chr8:41503840 NKX6-3 0.82 9.16 0.64 1.34e-15 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs62103177 0.810 rs62103192 chr18:77629050 A/T cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT trans rs2727020 0.521 rs1909220 chr11:49572109 T/C cg11707556 chr5:10655725 ANKRD33B -0.4 -7.59 -0.56 6.71e-12 Coronary artery disease; TGCT cis rs7954584 0.611 rs3887885 chr12:122336486 C/T cg13699009 chr12:122356056 WDR66 0.29 6.56 0.51 1.32e-9 Mean corpuscular volume; TGCT cis rs704 0.628 rs241775 chr17:26644668 C/T cg10494684 chr17:26645200 TMEM97 0.44 4.51 0.38 1.5e-5 Osteoprotegerin levels; TGCT cis rs7226408 0.842 rs62083201 chr18:34347836 A/G cg06757138 chr18:34340585 FHOD3 0.29 5.15 0.42 1.01e-6 Obesity-related traits; TGCT cis rs1552244 1.000 rs56270432 chr3:10087517 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT trans rs28595532 0.748 rs72670258 chr4:119391660 A/T cg26518628 chr1:97050305 NA -0.54 -6.79 -0.52 4.14e-10 Cannabis dependence symptom count; TGCT trans rs916888 0.773 rs199457 chr17:44795469 C/T cg07870213 chr5:140052090 DND1 0.67 7.94 0.58 1.03e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs208520 0.690 rs4710311 chr6:66823223 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.89 -8.9 -0.62 5.76e-15 Exhaled nitric oxide output; TGCT cis rs80282103 0.867 rs74117668 chr10:1076620 C/T cg18964960 chr10:1102726 WDR37 1.09 4.69 0.39 7.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs2070488 0.804 rs1870914 chr3:38494220 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.77 7.45 0.56 1.37e-11 Electrocardiographic conduction measures; TGCT cis rs9486719 1.000 rs10872018 chr6:97026429 G/A cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs523522 0.962 rs3893104 chr12:120903936 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.54 0.51 1.46e-9 High light scatter reticulocyte count; TGCT cis rs4891159 0.790 rs72975925 chr18:74143902 G/A cg24786174 chr18:74118243 ZNF516 -0.53 -7.05 -0.53 1.12e-10 Longevity; TGCT cis rs6121246 0.909 rs2376992 chr20:30263418 T/C cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs3540 0.618 rs11609 chr15:91043765 C/G cg22089800 chr15:90895588 ZNF774 -0.75 -7.58 -0.56 6.9e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs514406 0.644 rs7552663 chr1:53204352 C/T cg22166914 chr1:53195759 ZYG11B -0.46 -8.42 -0.6 7.72e-14 Monocyte count; TGCT cis rs208520 0.690 rs12201156 chr6:66720874 G/T cg07460842 chr6:66804631 NA 0.95 10.11 0.67 6.77e-18 Exhaled nitric oxide output; TGCT cis rs16957091 0.647 rs28796057 chr15:43188764 C/T cg17935677 chr15:44119062 WDR76 0.52 4.71 0.39 6.44e-6 MGMT methylation in smokers; TGCT cis rs7208859 0.673 rs423151 chr17:28952286 A/G cg04154034 chr17:28927549 LRRC37B2 0.78 4.98 0.41 2.07e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.830 rs4292342 chr4:98959870 A/T cg17366294 chr4:99064904 C4orf37 0.71 7.35 0.55 2.35e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12681287 0.547 rs7837569 chr8:87507366 C/T cg27223183 chr8:87520930 FAM82B -0.95 -6.95 -0.53 1.81e-10 Caudate activity during reward; TGCT cis rs7236492 0.515 rs76804350 chr18:77180607 C/T cg15644404 chr18:77186268 NFATC1 -0.43 -4.5 -0.37 1.57e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs1975974 0.935 rs11870387 chr17:21730236 G/C cg18423549 chr17:21743878 NA -0.58 -5.39 -0.44 3.34e-7 Psoriasis; TGCT cis rs7914558 0.966 rs2065977 chr10:104729415 C/T cg04362960 chr10:104952993 NT5C2 0.6 5.34 0.43 4.34e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs57221529 0.709 rs72703034 chr5:577101 C/T cg09021430 chr5:549028 NA -0.37 -5.16 -0.42 9.7e-7 Lung disease severity in cystic fibrosis; TGCT cis rs231513 0.911 rs124722 chr17:41956002 T/G cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs7260538 0.773 rs1552223 chr19:41525952 A/G cg27089200 chr19:41531976 NA -0.41 -5.5 -0.44 2.06e-7 DDT metabolite (p,p'-DDE levels); TGCT cis rs6554196 0.743 rs6831020 chr4:55500226 C/A cg02821500 chr4:54931072 CHIC2 0.49 4.45 0.37 1.89e-5 Monocyte count; TGCT cis rs1862618 0.853 rs6450409 chr5:56101399 A/G cg20203395 chr5:56204925 C5orf35 -0.56 -4.8 -0.4 4.39e-6 Initial pursuit acceleration; TGCT cis rs4654899 0.897 rs3736880 chr1:21097727 G/A cg01072550 chr1:21505969 NA -0.49 -7.89 -0.58 1.37e-12 Superior frontal gyrus grey matter volume; TGCT cis rs12908161 0.853 rs11633788 chr15:85305142 T/A cg17173187 chr15:85201210 NMB 0.41 4.82 0.4 4.2e-6 Schizophrenia; TGCT cis rs733175 0.855 rs10022499 chr4:10006537 C/A cg11266682 chr4:10021025 SLC2A9 0.47 4.63 0.38 9.05e-6 Psychosis and Alzheimer's disease; TGCT cis rs2440129 0.611 rs1042356 chr17:6902743 G/A cg03404566 chr17:6899310 ALOX12 0.44 5.15 0.42 9.77e-7 Tonsillectomy; TGCT cis rs9467711 0.659 rs36033628 chr6:26456074 T/G cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.798 rs6732579 chr2:99560239 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -5.79 -0.46 5.36e-8 Chronic sinus infection; TGCT cis rs7582180 0.625 rs11892034 chr2:100938952 T/C cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs965706 chr6:8464708 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs4372836 0.729 rs6547874 chr2:28982030 A/G cg09522027 chr2:28974177 PPP1CB -0.68 -6.93 -0.53 2e-10 Body mass index; TGCT cis rs2243480 0.803 rs55700941 chr7:65389800 T/A cg18252515 chr7:66147081 NA -1.14 -6.81 -0.52 3.76e-10 Diabetic kidney disease; TGCT cis rs7119038 0.779 rs73005502 chr11:118697906 A/G cg19308663 chr11:118741387 NA 0.3 5.88 0.47 3.49e-8 Sjögren's syndrome; TGCT cis rs7772486 0.534 rs34541797 chr6:146205304 A/G cg13319975 chr6:146136371 FBXO30 -0.63 -5.67 -0.45 9.51e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769765 0.542 rs5770725 chr22:50256309 C/T cg22709217 chr22:50311962 ALG12;CRELD2 1.02 6.31 0.49 4.46e-9 Schizophrenia; TGCT cis rs854765 0.583 rs8078105 chr17:17853782 T/C cg09796270 chr17:17721594 SREBF1 0.23 4.55 0.38 1.27e-5 Total body bone mineral density; TGCT cis rs10510102 0.872 rs7077035 chr10:123706645 A/G cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT trans rs2727020 0.658 rs7111215 chr11:49430552 T/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.26 -0.6 1.91e-13 Coronary artery disease; TGCT cis rs1153858 1.000 rs12909158 chr15:45621174 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.65 0.45 1.05e-7 Homoarginine levels; TGCT cis rs36051895 0.623 rs76960049 chr9:5064548 G/A cg02405213 chr9:5042618 JAK2 -0.83 -12.29 -0.74 3.38e-23 Pediatric autoimmune diseases; TGCT cis rs2594989 0.831 rs7651886 chr3:11572728 A/G cg26283222 chr3:11613257 VGLL4 -0.2 -4.45 -0.37 1.89e-5 Circulating chemerin levels; TGCT cis rs9905704 0.624 rs34718875 chr17:57072461 G/A cg05425664 chr17:57184151 TRIM37 -0.61 -5.09 -0.42 1.3e-6 Testicular germ cell tumor; TGCT cis rs548987 0.529 rs6456703 chr6:25826119 C/T cg03264133 chr6:25882463 NA -0.54 -4.44 -0.37 1.99e-5 Homocysteine levels; TGCT cis rs11018874 0.735 rs4307680 chr11:89900630 A/C cg05041596 chr11:89867385 NAALAD2 0.55 5.07 0.41 1.4e-6 White blood cell types; TGCT trans rs114540395 0.858 rs76807333 chr10:103234534 C/T cg10198749 chr1:39920707 MACF1 0.55 7.12 0.54 7.73e-11 Schizophrenia; TGCT cis rs6840360 0.555 rs4554052 chr4:152726610 T/C cg22705602 chr4:152727874 NA 0.33 6.0 0.47 2.01e-8 Intelligence (multi-trait analysis); TGCT cis rs6460942 0.915 rs62447638 chr7:12484667 G/A cg06484146 chr7:12443880 VWDE -0.61 -5.43 -0.44 2.87e-7 Coronary artery disease; TGCT cis rs3792900 0.509 rs6596299 chr5:135570567 A/C cg16684184 chr5:135415129 NA 0.26 4.83 0.4 3.96e-6 Insomnia;Blood protein levels; TGCT cis rs4953076 0.574 rs4953074 chr2:44464629 C/T cg04920474 chr2:44395004 PPM1B 0.59 5.91 0.47 3.04e-8 Height; TGCT cis rs74054849 0.717 rs3856275 chr1:15918676 C/T cg05660106 chr1:15850417 CASP9 -0.81 -4.5 -0.37 1.54e-5 Alcoholic chronic pancreatitis; TGCT cis rs3617 0.539 rs11130331 chr3:52956918 G/A cg11645453 chr3:52864694 ITIH4 -0.28 -5.39 -0.44 3.41e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9926296 1.000 rs9926296 chr16:89818089 A/G cg04287289 chr16:89883240 FANCA 0.78 8.6 0.61 2.98e-14 Vitiligo; TGCT cis rs72945132 0.882 rs7128969 chr11:70205017 C/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs2710642 0.962 rs7567923 chr2:63085848 C/T cg17519650 chr2:63277830 OTX1 -0.59 -5.34 -0.43 4.28e-7 LDL cholesterol levels;LDL cholesterol; TGCT cis rs494003 1.000 rs72922733 chr11:65520746 A/G cg04293602 chr11:65553660 OVOL1 0.37 4.77 0.39 5.13e-6 Systemic lupus erythematosus; TGCT cis rs35883536 0.565 rs2647322 chr1:101031962 G/T cg06223162 chr1:101003688 GPR88 0.42 8.14 0.59 3.53e-13 Monocyte count; TGCT cis rs2243480 1.000 rs709607 chr7:65449541 C/G cg18252515 chr7:66147081 NA 1.27 7.7 0.57 3.73e-12 Diabetic kidney disease; TGCT cis rs4819052 0.851 rs7276591 chr21:46680156 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9640161 0.789 rs34311995 chr7:150059255 T/C cg10018233 chr7:150070692 REPIN1 0.31 4.62 0.38 9.57e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs1218582 0.772 rs1976559 chr1:154879788 A/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs6815814 0.808 rs7673348 chr4:38845198 G/A cg02016764 chr4:38805732 TLR1 -0.29 -4.68 -0.39 7.51e-6 Breast cancer; TGCT cis rs35160687 0.901 rs11127026 chr2:86531748 C/T cg04877910 chr2:85804641 VAMP8 0.34 4.51 0.38 1.49e-5 Night sleep phenotypes; TGCT cis rs4294134 0.608 rs35229763 chr7:135246305 A/G cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs7267979 1.000 rs11100 chr20:25281184 G/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2463822 0.583 rs11600383 chr11:62060451 A/G cg23876832 chr11:62092739 NA 0.6 4.69 0.39 7.17e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs35146811 0.695 rs858508 chr7:99821381 C/G cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs1577917 0.798 rs7772384 chr6:86639680 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs933688 1.000 rs6862125 chr5:90724598 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.97 8.45 0.6 6.56e-14 Smoking behavior; TGCT cis rs2075371 0.966 rs2244690 chr7:133987039 A/G cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs1878931 0.501 rs28735976 chr16:3418419 G/A cg22508957 chr16:3507546 NAT15 -0.38 -4.98 -0.41 2.1e-6 Body mass index (adult); TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg17178900 chr1:205818956 PM20D1 0.58 7.02 0.53 1.27e-10 Menarche (age at onset); TGCT cis rs4889855 0.578 rs7216808 chr17:78484187 A/G cg16591659 chr17:78472290 NA -0.35 -5.57 -0.45 1.48e-7 Fractional excretion of uric acid; TGCT cis rs9443645 0.901 rs9443622 chr6:79582790 C/T cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.754 rs1051131 chr6:88221546 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs5769765 0.773 rs4075331 chr22:50302850 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -10.96 -0.7 5.67e-20 Schizophrenia; TGCT cis rs1799949 0.965 rs12950779 chr17:41306523 C/T cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs6089829 0.962 rs6062393 chr20:61663230 G/A cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1475911 1.000 rs55645900 chr21:43515728 G/T cg24372256 chr21:43528868 UMODL1;C21orf128 -0.27 -4.85 -0.4 3.56e-6 IgG glycosylation; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg01577475 chr2:114033581 PAX8;LOC440839 -0.44 -4.75 -0.39 5.42e-6 Lymphocyte counts; TGCT trans rs7824557 0.564 rs2572399 chr8:11234520 A/G cg15556689 chr8:8085844 FLJ10661 -0.74 -6.7 -0.52 6.42e-10 Retinal vascular caliber; TGCT cis rs909674 0.775 rs8138462 chr22:39839670 G/C cg11247378 chr22:39784982 NA -0.73 -8.98 -0.63 3.69e-15 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs3733585 0.638 rs6449155 chr4:9956547 T/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.73 -0.57 3.25e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg07424592 chr7:64974309 NA 1.11 8.02 0.58 6.87e-13 Diabetic kidney disease; TGCT cis rs7820838 0.548 rs6468119 chr8:32401561 A/G cg22651812 chr8:32095135 NRG1 -0.22 -4.79 -0.4 4.65e-6 Post bronchodilator FEV1/FVC ratio in COPD;Lung cancer; TGCT cis rs751728 0.664 rs2296744 chr6:33740382 G/A cg13859433 chr6:33739653 LEMD2 -0.32 -5.72 -0.46 7.4e-8 Crohn's disease; TGCT cis rs7666738 0.830 rs10012271 chr4:99065154 A/C cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10883723 0.810 rs7094366 chr10:104274730 C/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs858239 0.600 rs6960001 chr7:23130876 T/C cg05602783 chr7:23145260 KLHL7 -0.64 -5.37 -0.43 3.69e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6138458 1.000 rs227621 chr20:24910528 A/C cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT cis rs362296 0.698 rs362283 chr4:3259558 T/C cg06533319 chr4:3265114 C4orf44 0.24 4.45 0.37 1.86e-5 Parental longevity (mother's age at death); TGCT cis rs6570726 0.846 rs397311 chr6:145806701 C/T cg23711669 chr6:146136114 FBXO30 -0.7 -6.86 -0.52 2.9e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10509586 1.000 rs17503635 chr10:91734598 C/T cg25278353 chr10:91717815 NA 0.49 4.72 0.39 6.32e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs9942416 0.660 rs60423072 chr5:75006113 T/A cg19683494 chr5:74908142 NA 0.57 5.95 0.47 2.5e-8 Age-related disease endophenotypes; TGCT cis rs6543140 0.964 rs6734203 chr2:103080066 G/C cg09003973 chr2:102972529 NA 0.55 4.56 0.38 1.2e-5 Blood protein levels; TGCT cis rs6570726 0.738 rs7746330 chr6:145899257 A/C cg05347473 chr6:146136440 FBXO30 0.54 5.12 0.42 1.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.962 rs4809456 chr20:61660849 C/A cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs6918586 0.658 rs198830 chr6:26118246 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.68 -6.46 -0.5 2.15e-9 Schizophrenia; TGCT cis rs6089829 0.855 rs6090203 chr20:61663632 G/A cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467711 0.790 rs13204572 chr6:26189356 G/C cg16898833 chr6:26189333 HIST1H4D 1.44 6.24 0.49 6.22e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs7098414 0.511 rs7898787 chr10:82156042 G/A cg01528321 chr10:82214614 TSPAN14 0.56 4.98 0.41 2.07e-6 Post bronchodilator FEV1; TGCT cis rs12902680 0.739 rs1578910 chr15:46391797 G/A cg13605988 chr15:45421612 DUOX1;DUOXA1 0.32 4.5 0.37 1.56e-5 Neuroticism; TGCT cis rs10504229 0.683 rs16921829 chr8:58110950 A/G cg08280861 chr8:58055591 NA 0.41 4.66 0.39 8.1e-6 Developmental language disorder (linguistic errors); TGCT cis rs11731606 0.508 rs10000820 chr4:95313493 G/A cg00507259 chr4:95128692 SMARCAD1 0.65 4.8 0.4 4.43e-6 Mean platelet volume; TGCT cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs13108904 0.518 rs4974602 chr4:1342391 C/T cg03303774 chr4:1407052 NA 0.38 5.88 0.47 3.49e-8 Obesity-related traits; TGCT cis rs7666738 0.791 rs13149968 chr4:99070262 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12530845 1.000 rs6975251 chr7:135328689 C/G cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs17221829 0.710 rs12421890 chr11:89391799 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs7542091 0.579 rs34638782 chr1:210032055 C/G cg21951975 chr1:209979733 IRF6 0.48 4.89 0.4 3.01e-6 Monobrow; TGCT cis rs11250098 0.583 rs73196860 chr8:10814133 A/G cg16664915 chr8:10907788 XKR6 -0.31 -4.95 -0.41 2.35e-6 Morning vs. evening chronotype; TGCT cis rs7617773 0.780 rs13066758 chr3:48343877 G/A cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs7617773 0.817 rs35414021 chr3:48293524 G/C cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.64e-10 Coronary artery disease; TGCT cis rs7666738 0.830 rs28497822 chr4:98906873 C/T cg17366294 chr4:99064904 C4orf37 0.67 6.94 0.53 1.91e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2469997 1.000 rs2470008 chr8:120359366 C/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs732765 0.734 rs12323361 chr14:75171706 T/C cg06637938 chr14:75390232 RPS6KL1 -0.57 -4.97 -0.41 2.2e-6 Non-small cell lung cancer; TGCT cis rs1614887 1 rs1614887 chr6:26393021 A/G cg05738196 chr6:26577821 NA 0.5 5.21 0.42 7.66e-7 Intelligence (multi-trait analysis);Lobe attachment (rater-scored or self-reported); TGCT cis rs11578119 0.933 rs10919418 chr1:170443986 A/G cg09767346 chr1:170501363 GORAB -0.7 -5.48 -0.44 2.32e-7 Male-pattern baldness; TGCT cis rs422249 0.512 rs99780 chr11:61596633 C/T cg19610905 chr11:61596333 FADS2 -0.97 -9.93 -0.67 1.9e-17 Trans fatty acid levels; TGCT cis rs9341808 0.650 rs6909546 chr6:80869923 C/G cg08355045 chr6:80787529 NA 0.32 5.64 0.45 1.11e-7 Sitting height ratio; TGCT cis rs3749237 0.595 rs3924462 chr3:49524236 T/G cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs28595532 0.841 rs114107504 chr4:119771080 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs4788570 0.655 rs1392484 chr16:71822101 T/A cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.512 rs2899349 chr22:42164660 T/C cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs7659604 0.518 rs17452156 chr4:122733623 T/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.31 -0.43 4.82e-7 Type 2 diabetes; TGCT cis rs7180079 0.620 rs2733382 chr15:64856394 A/G cg03791955 chr15:65024147 NA -0.28 -4.46 -0.37 1.81e-5 Monocyte count; TGCT cis rs736408 0.608 rs35004449 chr3:52852897 G/T cg10802521 chr3:52805072 NEK4 -0.64 -6.51 -0.5 1.69e-9 Bipolar disorder; TGCT cis rs11190604 0.767 rs7078070 chr10:102166415 A/C cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9389248 0.690 rs2072826 chr6:135253558 G/C cg24558204 chr6:135376177 HBS1L -0.47 -4.81 -0.4 4.35e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs12643440 0.502 rs56163730 chr4:17143120 A/G cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs6430585 0.583 rs59213715 chr2:136646582 A/C cg07169764 chr2:136633963 MCM6 1.21 11.72 0.72 8.21e-22 Corneal structure; TGCT cis rs7937682 0.883 rs1784776 chr11:111472392 C/T cg09085632 chr11:111637200 PPP2R1B -1.07 -11.27 -0.71 1.04e-20 Primary sclerosing cholangitis; TGCT cis rs797680 0.789 rs7539307 chr1:93652703 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.03 -0.41 1.67e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6558530 0.730 rs10097891 chr8:1726809 C/A cg09410841 chr8:1729607 CLN8 0.85 9.98 0.67 1.44e-17 Systolic blood pressure; TGCT trans rs12599106 0.792 rs12597352 chr16:34638507 A/T cg03395511 chr6:291903 DUSP22 -0.64 -6.62 -0.51 9.7e-10 Menopause (age at onset); TGCT cis rs7267979 1.000 rs2424710 chr20:25283886 C/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7020830 0.898 rs13289199 chr9:37278064 A/T cg14294708 chr9:37120828 ZCCHC7 1.12 13.76 0.78 9.91e-27 Schizophrenia; TGCT cis rs1005224 1.000 rs1005224 chr14:76173860 A/T cg25116370 chr14:76127843 TTLL5;C14orf1 -0.55 -4.66 -0.39 8.03e-6 Large artery stroke; TGCT cis rs9660992 0.590 rs1779411 chr1:205238530 C/T cg00857998 chr1:205179979 DSTYK 0.52 4.54 0.38 1.29e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs11785400 0.731 rs4644221 chr8:143736984 C/T cg10596483 chr8:143751796 JRK -0.54 -5.49 -0.44 2.19e-7 Schizophrenia; TGCT cis rs796364 1.000 rs11694369 chr2:200741720 G/A cg17644776 chr2:200775616 C2orf69 -0.31 -4.69 -0.39 7.18e-6 Schizophrenia; TGCT cis rs7954584 0.545 rs12824593 chr12:122374108 G/A cg22168489 chr12:122356033 WDR66 0.22 4.78 0.39 4.96e-6 Mean corpuscular volume; TGCT cis rs938554 0.744 rs13129697 chr4:9926967 T/G cg00071950 chr4:10020882 SLC2A9 -0.5 -4.78 -0.39 4.93e-6 Blood metabolite levels; TGCT cis rs6459788 0.527 rs6980250 chr7:157228710 C/T cg03453431 chr7:157225567 NA -0.56 -9.25 -0.64 8.11e-16 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs910316 1.000 rs175436 chr14:75608683 C/G cg11812906 chr14:75593930 NEK9 -0.71 -6.67 -0.51 7.42e-10 Height; TGCT trans rs1814175 0.647 rs28456013 chr11:50047629 T/C cg15704280 chr7:45808275 SEPT13 -0.6 -6.79 -0.52 4.13e-10 Height; TGCT cis rs12142240 0.698 rs68112720 chr1:46813888 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7917772 0.502 rs10748827 chr10:104368336 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 8.21 0.59 2.44e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9914988 0.943 rs9902953 chr17:27139834 C/A cg20469991 chr17:27169893 C17orf63 -0.71 -4.97 -0.41 2.18e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg03161606 chr19:29218774 NA 0.6 5.79 0.46 5.33e-8 Methadone dose in opioid dependence; TGCT cis rs7178572 0.568 rs12900433 chr15:77495028 T/C cg22256960 chr15:77711686 NA -0.88 -8.99 -0.63 3.53e-15 Type 2 diabetes; TGCT cis rs7727544 0.548 rs4705938 chr5:131694077 A/G cg14196790 chr5:131705035 SLC22A5 0.34 4.59 0.38 1.06e-5 Blood metabolite levels; TGCT cis rs12580194 0.593 rs7313465 chr12:55736863 C/T cg10672482 chr12:55725839 OR6C3 -0.51 -4.6 -0.38 1.02e-5 Cancer; TGCT cis rs7072216 0.655 rs3830025 chr10:100176104 A/G cg26618903 chr10:100175079 PYROXD2 -0.42 -4.44 -0.37 1.93e-5 Metabolite levels; TGCT cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg13695892 chr22:41940480 POLR3H -0.87 -8.35 -0.6 1.14e-13 Vitiligo; TGCT trans rs12655019 0.920 rs6450410 chr5:56206701 A/G cg25190722 chr1:3801660 DFFB 0.62 7.17 0.54 5.87e-11 Breast cancer (early onset); TGCT cis rs12900413 0.603 rs12911871 chr15:90301429 T/C cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs2760061 0.626 rs2796057 chr1:228124414 G/C cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs7811142 0.830 rs6948685 chr7:99970188 C/T cg00814883 chr7:100076585 TSC22D4 -0.86 -8.76 -0.62 1.21e-14 Platelet count; TGCT cis rs79349575 0.783 rs4793996 chr17:47019597 T/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs7662987 0.517 rs3018048 chr4:100005538 C/T cg12011299 chr4:100065546 ADH4 0.38 4.71 0.39 6.42e-6 Smoking initiation; TGCT cis rs8180040 0.966 rs6765990 chr3:47542894 G/A cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs1552244 0.882 rs13099507 chr3:10031603 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 6.22 0.49 7.14e-9 Alzheimer's disease; TGCT cis rs6752107 0.967 rs10210302 chr2:234158839 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.86 0.4 3.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.28 -0.43 5.51e-7 Developmental language disorder (linguistic errors); TGCT cis rs10197940 0.662 rs2432945 chr2:152278414 T/C cg19508488 chr2:152266495 RIF1 0.74 6.66 0.51 7.77e-10 Lung cancer; TGCT cis rs4601821 0.823 rs10891546 chr11:113265292 C/T cg14159747 chr11:113255604 NA -0.45 -5.52 -0.44 1.91e-7 Alcoholic chronic pancreatitis; TGCT cis rs739496 0.615 rs2339818 chr12:112046476 T/C cg10833066 chr12:111807467 FAM109A 0.36 4.98 0.41 2.1e-6 Platelet count; TGCT cis rs9653442 0.527 rs10176782 chr2:100782827 C/A cg07810366 chr2:100720526 AFF3 -0.36 -5.26 -0.43 6.14e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6089584 0.888 rs6061981 chr20:60618973 T/C cg06108461 chr20:60628389 TAF4 -0.69 -10.77 -0.7 1.71e-19 Body mass index; TGCT cis rs9394169 0.818 rs1547671 chr6:33777260 C/T cg00334056 chr6:33755658 LEMD2 -0.23 -4.47 -0.37 1.76e-5 Essential tremor; TGCT cis rs1878931 0.501 rs17136359 chr16:3420814 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.77 -7.14 -0.54 7.09e-11 Body mass index (adult); TGCT cis rs9790314 0.846 rs12495310 chr3:160970956 T/A cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs473651 0.935 rs35080527 chr2:239351387 T/C cg08773314 chr2:239334832 ASB1 0.45 7.5 0.56 1.07e-11 Multiple system atrophy; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg02953382 chr22:24373134 LOC391322 0.77 8.01 0.58 7.12e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs644799 1.000 rs12786522 chr11:95522858 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 11.0 0.7 4.62e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9914544 0.564 rs1859083 chr17:18843306 C/T cg26378065 chr17:18585709 ZNF286B -0.49 -4.56 -0.38 1.21e-5 Educational attainment (years of education); TGCT cis rs2439831 0.717 rs28495368 chr15:43895642 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.93 6.64 0.51 8.7e-10 Lung cancer in ever smokers; TGCT cis rs4237845 0.537 rs7969844 chr12:58278271 C/T cg23860436 chr12:58378763 NA 0.34 4.75 0.39 5.48e-6 Intelligence (multi-trait analysis); TGCT cis rs6690583 0.623 rs12041012 chr1:85515644 G/A cg20280350 chr1:85513789 MCOLN3 -0.79 -4.99 -0.41 1.98e-6 Serum sulfate level; TGCT cis rs9926296 0.632 rs1800286 chr16:89869761 T/C cg27121462 chr16:89883253 FANCA 0.61 5.51 0.44 2.03e-7 Vitiligo; TGCT cis rs35883536 0.605 rs2133118 chr1:101034337 C/T cg10298815 chr1:101004474 GPR88 -0.25 -4.61 -0.38 9.74e-6 Monocyte count; TGCT cis rs9419702 0.538 rs9322837 chr10:133539229 G/A cg04492858 chr10:133558786 NA 0.57 6.1 0.48 1.25e-8 Survival in rectal cancer; TGCT cis rs2229238 0.911 rs6672087 chr1:154516122 A/C cg13067139 chr1:155221277 FAM189B 0.2 4.45 0.37 1.87e-5 Coronary heart disease; TGCT cis rs78487399 0.808 rs17031001 chr2:43761218 T/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -4.72 -0.39 6.22e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs769267 0.965 rs2269873 chr19:19392401 T/C cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs9928842 0.882 rs8048956 chr16:75254966 C/G cg09066997 chr16:75300724 BCAR1 -0.27 -5.02 -0.41 1.79e-6 Alcoholic chronic pancreatitis; TGCT cis rs3809566 0.963 rs12148057 chr15:63331509 A/T cg00520135 chr15:63333846 TPM1 -0.44 -5.46 -0.44 2.44e-7 Platelet count; TGCT cis rs6598955 1.000 rs10902728 chr1:26598281 T/C cg04990556 chr1:26633338 UBXN11 0.84 9.5 0.65 2e-16 Obesity-related traits; TGCT cis rs9486719 1.000 rs12208011 chr6:96991105 G/A cg18709589 chr6:96969512 KIAA0776 -0.76 -5.32 -0.43 4.63e-7 Migraine;Coronary artery disease; TGCT cis rs4319547 0.626 rs12423420 chr12:122938466 G/A cg23029597 chr12:123009494 RSRC2 -0.27 -4.46 -0.37 1.8e-5 Body mass index; TGCT cis rs709400 0.663 rs11623869 chr14:103883633 G/T cg12935359 chr14:103987150 CKB -0.35 -5.33 -0.43 4.54e-7 Body mass index; TGCT cis rs9634489 0.502 rs9513143 chr13:97085570 A/G cg11411106 chr13:97107445 HS6ST3 -0.28 -5.13 -0.42 1.09e-6 Body mass index; TGCT cis rs873946 0.648 rs3793673 chr10:134547732 A/C cg27286337 chr10:134555280 INPP5A 0.43 5.08 0.42 1.33e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs303386 0.501 rs4908302 chr1:99583122 A/C cg03593336 chr1:99471295 LPPR5 0.27 5.54 0.45 1.7e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors);Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin); TGCT cis rs4819052 0.819 rs34818688 chr21:46672416 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8028182 0.636 rs8036758 chr15:75817562 G/A cg20655648 chr15:75932815 IMP3 0.6 4.65 0.38 8.54e-6 Sudden cardiac arrest; TGCT cis rs523522 0.602 rs7132474 chr12:120866996 A/C cg12219531 chr12:120966889 COQ5 0.72 4.88 0.4 3.18e-6 High light scatter reticulocyte count; TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg24675658 chr1:53192096 ZYG11B -0.71 -7.72 -0.57 3.38e-12 Monocyte count; TGCT cis rs7172809 0.548 rs11856513 chr15:77471105 A/C cg22256960 chr15:77711686 NA 0.49 4.44 0.37 1.95e-5 Glucose homeostasis traits; TGCT cis rs6121246 0.567 rs2889488 chr20:30185758 G/A cg13852791 chr20:30311386 BCL2L1 0.69 4.65 0.39 8.44e-6 Mean corpuscular hemoglobin; TGCT cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs36051895 0.559 rs72701682 chr9:5208025 A/G cg02405213 chr9:5042618 JAK2 -0.63 -7.47 -0.56 1.25e-11 Pediatric autoimmune diseases; TGCT cis rs2797160 0.875 rs12527010 chr6:125991507 A/G cg05901451 chr6:126070800 HEY2 0.79 7.42 0.55 1.65e-11 Endometrial cancer; TGCT trans rs1005277 0.522 rs289643 chr10:37941494 T/G cg17830980 chr10:43048298 ZNF37B -0.65 -7.09 -0.54 9.18e-11 Extrinsic epigenetic age acceleration; TGCT cis rs8062405 0.754 rs62034323 chr16:28536473 C/T cg09754948 chr16:28834200 ATXN2L 0.58 4.57 0.38 1.14e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6831352 0.918 rs35662508 chr4:100050974 C/G cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs600231 0.665 rs2846861 chr11:65222305 A/G cg17120908 chr11:65337727 SSSCA1 -0.51 -4.71 -0.39 6.59e-6 Bone mineral density; TGCT cis rs9928842 0.824 rs12924999 chr16:75262425 T/G cg09066997 chr16:75300724 BCAR1 0.28 5.01 0.41 1.85e-6 Alcoholic chronic pancreatitis; TGCT cis rs478304 0.934 rs570954 chr11:65498261 A/G cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.18e-7 Acne (severe); TGCT cis rs975752 0.867 rs4919440 chr10:102014919 C/T cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs17376456 0.877 rs9314092 chr5:93326362 A/G cg21475434 chr5:93447410 FAM172A 0.66 4.97 0.41 2.2e-6 Diabetic retinopathy; TGCT cis rs617219 0.698 rs7706045 chr5:78507910 T/G cg05890484 chr5:78407552 BHMT 0.38 5.2 0.42 8.14e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs873946 0.648 rs3750578 chr10:134563366 A/G cg18305652 chr10:134549665 INPP5A 0.34 5.75 0.46 6.43e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs539096 0.671 rs513862 chr1:44114405 A/T cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Intelligence (multi-trait analysis); TGCT cis rs12136530 0.625 rs4912086 chr1:19730181 A/G cg24875000 chr1:19041556 PAX7 -0.25 -4.47 -0.37 1.72e-5 Lead levels in blood; TGCT cis rs10256972 0.577 rs6962809 chr7:1208889 A/G cg18765753 chr7:1198926 ZFAND2A -0.53 -6.58 -0.51 1.18e-9 Longevity;Endometriosis; TGCT cis rs1568889 0.838 rs11030206 chr11:28099747 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.34 0.71 7.08e-21 Bipolar disorder; TGCT cis rs73198271 0.640 rs7838012 chr8:8656630 A/G cg06671706 chr8:8559999 CLDN23 -0.36 -4.52 -0.38 1.42e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs73815153 0.744 rs10479600 chr5:180459653 G/A cg00299286 chr5:180478185 BTNL9 0.87 4.98 0.41 2.08e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs10851411 0.789 rs28886308 chr15:42770032 A/G cg23803468 chr15:43513504 EPB42 0.23 4.53 0.38 1.36e-5 Glucose homeostasis traits; TGCT cis rs6500602 0.702 rs9929475 chr16:4540885 C/T cg08645402 chr16:4508243 NA -0.17 -4.66 -0.39 8.09e-6 Schizophrenia; TGCT cis rs8077889 0.956 rs55768269 chr17:41888997 C/T cg26893861 chr17:41843967 DUSP3 1.1 12.5 0.75 1.08e-23 Triglycerides; TGCT cis rs4654899 0.865 rs61779065 chr1:21356474 A/T cg01072550 chr1:21505969 NA -0.46 -6.95 -0.53 1.88e-10 Superior frontal gyrus grey matter volume; TGCT cis rs10056811 0.556 rs57441318 chr5:74379675 T/A cg19683494 chr5:74908142 NA 0.58 5.17 0.42 9.04e-7 Coronary artery disease; TGCT cis rs12048904 0.595 rs10493937 chr1:101342650 A/T cg16556008 chr1:101360663 SLC30A7;EXTL2 -0.72 -7.67 -0.57 4.42e-12 Multiple sclerosis; TGCT cis rs4850410 0.581 rs12997637 chr2:197909347 T/G cg19149314 chr2:197065128 HECW2 0.23 4.47 0.37 1.77e-5 Interferon alpha levels in systemic lupus erythematosus; TGCT cis rs3845702 0.736 rs72960664 chr2:180832672 C/T cg01881094 chr2:180872142 CWC22 1.04 6.58 0.51 1.16e-9 Schizophrenia; TGCT cis rs9467773 0.620 rs2494694 chr6:26619328 A/T cg05738196 chr6:26577821 NA 0.87 11.3 0.71 8.47e-21 Intelligence (multi-trait analysis); TGCT cis rs4824093 0.535 rs73443931 chr22:50291603 G/A cg14114931 chr22:50943910 LMF2 0.37 4.58 0.38 1.11e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs9787249 0.957 rs7548120 chr1:40204424 A/T cg19912559 chr1:40204330 PPIE 0.49 5.7 0.46 8.41e-8 Blood protein levels; TGCT cis rs17376456 0.825 rs10476590 chr5:93244884 A/T cg21475434 chr5:93447410 FAM172A 0.71 4.91 0.4 2.86e-6 Diabetic retinopathy; TGCT trans rs1814175 0.817 rs10839465 chr11:49981554 C/A cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs7726839 0.507 rs72703100 chr5:614291 C/T cg09021430 chr5:549028 NA -0.46 -6.07 -0.48 1.42e-8 Obesity-related traits; TGCT cis rs9467773 0.565 rs4343916 chr6:26522675 A/T cg09904177 chr6:26538194 HMGN4 0.5 4.76 0.39 5.25e-6 Intelligence (multi-trait analysis); TGCT cis rs12210905 0.920 rs12191414 chr6:27278634 C/G cg08851530 chr6:28072375 NA 1.29 5.26 0.43 6.03e-7 Hip circumference adjusted for BMI; TGCT cis rs4654899 0.802 rs12123910 chr1:21233316 C/T cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs11190604 1.000 rs10883499 chr10:102232188 T/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1862618 0.671 rs28397234 chr5:56248428 T/G cg12311346 chr5:56204834 C5orf35 0.57 6.09 0.48 1.28e-8 Initial pursuit acceleration; TGCT cis rs7192750 0.519 rs2008675 chr16:71995980 A/C cg06353428 chr16:71660113 MARVELD3 0.76 6.53 0.51 1.53e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs929354 1.000 rs1182377 chr7:157048403 T/C cg05182265 chr7:156933206 UBE3C 0.32 6.63 0.51 9.08e-10 Body mass index; TGCT cis rs2836950 0.502 rs2150411 chr21:40574552 G/T cg11890956 chr21:40555474 PSMG1 -0.68 -6.6 -0.51 1.09e-9 Menarche (age at onset); TGCT cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs34638657 0.732 rs62045962 chr16:82200604 T/C cg09439754 chr16:82129088 HSD17B2 -0.24 -4.63 -0.38 9.27e-6 Lung adenocarcinoma; TGCT cis rs7027203 0.964 rs6479512 chr9:96556985 G/A cg14598338 chr9:96623480 NA 0.6 8.72 0.62 1.51e-14 DNA methylation (variation); TGCT cis rs9399137 0.507 rs6923512 chr6:135335268 A/G cg24558204 chr6:135376177 HBS1L -0.46 -4.65 -0.39 8.3e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg26118208 chr10:134322334 NA 0.26 5.21 0.42 7.56e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7246657 0.943 rs2891699 chr19:37920237 A/G cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9368481 0.761 rs3931464 chr6:26939856 C/A cg26531700 chr6:26746687 NA 0.61 5.65 0.45 1.06e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs151997 1.000 rs27249 chr5:50232678 A/G cg06027927 chr5:50259733 NA 0.47 4.8 0.4 4.41e-6 Callous-unemotional behaviour; TGCT cis rs526231 0.575 rs12652973 chr5:102306322 G/A cg23492399 chr5:102201601 PAM -0.53 -4.56 -0.38 1.23e-5 Primary biliary cholangitis; TGCT cis rs1348850 0.872 rs4893959 chr2:178400204 G/A cg22681709 chr2:178499509 PDE11A -0.38 -4.73 -0.39 6.12e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9814567 1.000 rs6785027 chr3:134211649 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.93 9.4 0.64 3.66e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs236907 0.859 rs34320898 chr1:171759139 G/C cg20598894 chr1:171756153 METTL13 -0.2 -4.54 -0.38 1.31e-5 Mean platelet volume; TGCT cis rs9527 0.640 rs6584541 chr10:104929124 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.63 -0.38 9.04e-6 Arsenic metabolism; TGCT cis rs597539 0.652 rs627731 chr11:68698663 A/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.8 7.43 0.55 1.56e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7267979 1.000 rs2482943 chr20:25380593 G/A cg03522245 chr20:25566470 NINL -0.64 -7.05 -0.53 1.12e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2204008 0.811 rs11525004 chr12:38333807 T/A cg13010199 chr12:38710504 ALG10B 0.59 4.53 0.38 1.37e-5 Bladder cancer; TGCT cis rs7666738 0.861 rs5010991 chr4:98972179 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7017914 0.905 rs1908034 chr8:71922554 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs986417 0.901 rs1884098 chr14:61038944 A/T cg18240143 chr14:60952599 C14orf39 0.94 5.09 0.42 1.29e-6 Gut microbiota (bacterial taxa); TGCT cis rs2404602 0.716 rs17363713 chr15:76746128 G/C cg26408565 chr15:76604113 ETFA -0.4 -5.26 -0.43 6.23e-7 Blood metabolite levels; TGCT cis rs909674 0.818 rs5750833 chr22:39843091 C/A cg24399712 chr22:39784796 NA -1.04 -11.0 -0.7 4.62e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs6815814 0.904 rs7664239 chr4:38786304 T/C cg02016764 chr4:38805732 TLR1 -0.28 -4.59 -0.38 1.06e-5 Breast cancer; TGCT cis rs4455778 0.659 rs4917196 chr7:49021759 C/T cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs7681440 0.904 rs2301134 chr4:90758945 A/G cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.87e-8 Dementia with Lewy bodies; TGCT cis rs9814567 1.000 rs4498009 chr3:134198008 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.97 -9.24 -0.64 8.89e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs35000415 0.938 rs12531711 chr7:128617466 A/G cg06242719 chr7:129414860 MIR183;MIR96 -0.31 -4.52 -0.38 1.4e-5 Systemic lupus erythematosus; TGCT cis rs76935404 1.000 rs76935404 chr19:41419294 C/T cg19493303 chr19:41414353 NA 0.42 5.11 0.42 1.17e-6 nicotine metabolite ratio in current smokers; TGCT cis rs12188164 0.965 rs1056465 chr5:442438 T/A cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs7830933 0.955 rs1550279 chr8:23600854 C/G cg04349084 chr8:23602677 NA 0.24 4.88 0.4 3.24e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs7666738 0.606 rs10006454 chr4:99080361 G/A cg17366294 chr4:99064904 C4orf37 0.57 5.34 0.43 4.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9814567 1.000 rs1874883 chr3:134205071 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -9.97 -0.67 1.5e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7666738 0.830 rs28618180 chr4:98912184 A/C cg18180107 chr4:99064573 C4orf37 0.53 4.99 0.41 1.98e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2562456 0.792 rs2562398 chr19:21722949 A/G cg25650185 chr19:21324782 ZNF431 0.64 5.7 0.46 8.3e-8 Pain; TGCT cis rs9611565 0.512 rs964898 chr22:42142306 C/T cg13695892 chr22:41940480 POLR3H -0.81 -7.54 -0.56 8.75e-12 Vitiligo; TGCT cis rs7917772 0.503 rs7896841 chr10:104294665 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg00786635 chr1:25594202 NA 0.54 5.78 0.46 5.67e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs9811920 0.809 rs793464 chr3:99626028 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.46 -5.2 -0.42 7.88e-7 Axial length; TGCT cis rs6933660 0.800 rs6930557 chr6:151755806 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.94 -10.66 -0.69 3.05e-19 Menarche (age at onset); TGCT cis rs7267979 0.966 rs4815425 chr20:25398876 G/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6674176 0.628 rs3828146 chr1:44428715 C/T cg12908607 chr1:44402522 ARTN -0.67 -8.15 -0.59 3.4e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs826838 0.967 rs11168985 chr12:39045983 A/C cg13010199 chr12:38710504 ALG10B -0.68 -5.16 -0.42 9.31e-7 Heart rate; TGCT cis rs3733585 0.664 rs17245436 chr4:9958169 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.71e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2204008 0.538 rs11514000 chr12:38067706 A/G cg26384229 chr12:38710491 ALG10B 0.59 5.06 0.41 1.47e-6 Bladder cancer; TGCT cis rs9814567 0.964 rs4974480 chr3:134178562 A/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -9.92 -0.67 2.01e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4888262 0.526 rs4404098 chr16:74570050 G/A cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 8.09e-11 Testicular germ cell tumor; TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg09060608 chr5:178986726 RUFY1 0.63 7.96 0.58 9.3e-13 Lung cancer; TGCT cis rs1322512 0.959 rs1744375 chr6:152944464 C/T cg03415253 chr6:152958462 SYNE1 -0.57 -4.98 -0.41 2.05e-6 Tonometry; TGCT cis rs12541335 0.639 rs68063696 chr8:22153236 A/G cg26039829 chr8:22132926 PIWIL2 0.26 4.73 0.39 5.98e-6 Hypertriglyceridemia; TGCT cis rs17376456 0.569 rs68122392 chr5:93077807 A/T cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg21226059 chr5:178986404 RUFY1 0.57 6.46 0.5 2.12e-9 Lung cancer; TGCT cis rs2066819 1.000 rs11575234 chr12:56744276 C/G cg26714650 chr12:56694279 CS -1.44 -7.47 -0.56 1.26e-11 Psoriasis vulgaris; TGCT cis rs7618915 0.501 rs62253740 chr3:52684128 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs3820928 1.000 rs7561378 chr2:227772248 T/C cg11843606 chr2:227700838 RHBDD1 -0.54 -4.82 -0.4 4.12e-6 Pulmonary function; TGCT cis rs2228479 0.850 rs12596934 chr16:89841605 T/G cg06558623 chr16:89946397 TCF25 0.45 4.52 0.38 1.42e-5 Skin colour saturation; TGCT cis rs3772130 0.962 rs1920320 chr3:121547527 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs910316 1.000 rs876403 chr14:75602834 A/T cg11812906 chr14:75593930 NEK9 0.73 7.1 0.54 8.42e-11 Height; TGCT cis rs7666738 0.819 rs13120307 chr4:99036100 A/C cg18180107 chr4:99064573 C4orf37 0.59 5.37 0.43 3.73e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs17221829 0.733 rs1962259 chr11:89380637 G/C cg02982614 chr11:89391479 FOLH1B -0.27 -4.85 -0.4 3.63e-6 Anxiety in major depressive disorder; TGCT cis rs6714710 0.603 rs11691494 chr2:98419726 T/A cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7424096 0.582 rs7600245 chr2:37220614 A/C cg14987922 chr2:37194071 STRN 0.52 4.53 0.38 1.37e-5 High light scatter reticulocyte percentage of red cells; TGCT cis rs12257961 0.549 rs1955342 chr10:15377871 A/G cg10616319 chr10:15468812 NA -0.25 -4.56 -0.38 1.2e-5 Selective IgA deficiency; TGCT cis rs826838 1.000 rs11183196 chr12:38685915 G/T cg13010199 chr12:38710504 ALG10B 0.82 6.65 0.51 8.46e-10 Heart rate; TGCT cis rs6951245 0.580 rs78894484 chr7:1138721 T/G cg03188948 chr7:1209495 NA 0.52 5.4 0.44 3.29e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7267979 1.000 rs2424712 chr20:25416942 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 1.000 rs73607874 chr8:58173433 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs853679 0.517 rs9380055 chr6:28081629 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs12477438 0.501 rs6708878 chr2:99801564 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs7584330 0.554 rs6740834 chr2:238423442 T/C cg08992911 chr2:238395768 MLPH 0.76 5.32 0.43 4.77e-7 Prostate cancer; TGCT cis rs2637266 1.000 rs2637268 chr10:78332213 G/T cg18941641 chr10:78392320 NA 0.39 4.97 0.41 2.16e-6 Pulmonary function; TGCT cis rs644799 0.511 rs1016030 chr11:95472693 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.6 5.86 0.47 3.96e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4862750 0.872 rs13101408 chr4:187894777 G/A cg11301795 chr4:187892539 NA -0.34 -4.9 -0.4 2.97e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1372520 0.748 rs1471484 chr4:90754313 C/T cg01966878 chr4:90757139 SNCA -0.3 -4.62 -0.38 9.66e-6 Neuroticism; TGCT cis rs9910055 0.614 rs12944572 chr17:42245241 T/C cg13607699 chr17:42295918 UBTF 0.59 5.45 0.44 2.61e-7 Total body bone mineral density; TGCT cis rs1018836 0.537 rs13251501 chr8:91458796 G/A cg16814680 chr8:91681699 NA -0.76 -6.99 -0.53 1.5e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs10883723 0.810 rs7094366 chr10:104274730 C/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9549367 0.789 rs9549365 chr13:113907391 C/T cg18105134 chr13:113819100 PROZ 0.35 5.89 0.47 3.45e-8 Platelet distribution width; TGCT cis rs6840360 0.593 rs4696106 chr4:152606818 A/G cg22705602 chr4:152727874 NA -0.32 -5.27 -0.43 5.96e-7 Intelligence (multi-trait analysis); TGCT cis rs2404602 0.692 rs34287706 chr15:76942402 A/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs17152411 1.000 rs1065301 chr10:126616038 A/G cg07906193 chr10:126599966 NA 0.41 5.12 0.42 1.12e-6 Height; TGCT cis rs4819052 0.851 rs10470258 chr21:46658989 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs600231 0.706 rs1111934 chr11:65329392 A/G cg13974409 chr11:65292307 SCYL1 0.5 4.91 0.4 2.78e-6 Bone mineral density; TGCT cis rs9790314 0.586 rs11713185 chr3:161111357 C/G cg03342759 chr3:160939853 NMD3 -0.55 -5.7 -0.46 8.15e-8 Morning vs. evening chronotype; TGCT cis rs2486288 0.656 rs9921035 chr15:45546660 C/T cg14582100 chr15:45693742 SPATA5L1 -0.41 -4.95 -0.41 2.36e-6 Glomerular filtration rate; TGCT cis rs35000415 0.506 rs34288126 chr7:128735438 G/A cg06242719 chr7:129414860 MIR183;MIR96 -0.32 -4.66 -0.39 7.91e-6 Systemic lupus erythematosus; TGCT cis rs1055129 0.655 rs8067076 chr17:73837142 G/T cg08125733 chr17:73851984 WBP2 -0.52 -4.68 -0.39 7.42e-6 White matter hyperintensity burden; TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg16325326 chr1:53192061 ZYG11B 0.56 6.12 0.48 1.15e-8 Monocyte count; TGCT cis rs10782582 0.609 rs1796815 chr1:76396793 T/G cg10523679 chr1:76189770 ACADM -0.55 -4.94 -0.41 2.5e-6 Daytime sleep phenotypes; TGCT cis rs231513 0.954 rs231508 chr17:41967583 G/A cg26893861 chr17:41843967 DUSP3 -0.71 -5.25 -0.43 6.26e-7 Cognitive function; TGCT cis rs2204008 0.580 rs1315373 chr12:38179114 T/G cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs2224391 0.628 rs766340 chr6:5243521 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs13242816 1.000 rs17138714 chr7:116114274 C/T cg02799643 chr7:116139180 CAV2 -0.43 -5.22 -0.42 7.45e-7 P wave duration; TGCT cis rs7833790 0.724 rs4739627 chr8:82734657 A/G cg06027949 chr8:82754900 SNX16 -0.65 -5.03 -0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs2288884 1.000 rs11673286 chr19:52540318 C/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.6 -0.38 1.03e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs4819052 0.851 rs7275874 chr21:46671223 C/T cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7726839 0.555 rs4541696 chr5:581053 A/G cg09021430 chr5:549028 NA -0.46 -8.99 -0.63 3.47e-15 Obesity-related traits; TGCT cis rs1403694 0.515 rs1648722 chr3:186448989 C/T cg12454167 chr3:186435060 KNG1 0.46 7.19 0.54 5.47e-11 Blood protein levels; TGCT cis rs9325144 0.510 rs6582599 chr12:38715965 T/G cg26384229 chr12:38710491 ALG10B 0.64 6.0 0.47 2.03e-8 Morning vs. evening chronotype; TGCT cis rs7027203 0.538 rs10125195 chr9:96523224 T/C cg13679303 chr9:96623674 NA -0.53 -7.48 -0.56 1.18e-11 DNA methylation (variation); TGCT trans rs12599106 0.818 rs17723574 chr16:34602945 C/G cg21548813 chr6:291882 DUSP22 -0.63 -6.65 -0.51 8.55e-10 Menopause (age at onset); TGCT cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg16414030 chr3:133502952 NA -0.5 -7.12 -0.54 7.86e-11 Iron status biomarkers; TGCT cis rs912057 0.833 rs1294426 chr6:6744477 T/C cg06612196 chr6:6737390 NA 0.37 4.88 0.4 3.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs17376456 0.877 rs35075119 chr5:93385457 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs9650657 0.711 rs35091929 chr8:10693492 T/C cg27411982 chr8:10470053 RP1L1 -0.24 -4.96 -0.41 2.24e-6 Neuroticism; TGCT cis rs7666738 0.830 rs6831925 chr4:98947401 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9308731 0.966 rs6753785 chr2:111923630 T/G cg04202892 chr2:111875749 ACOXL 0.44 4.88 0.4 3.18e-6 Chronic lymphocytic leukemia; TGCT cis rs1150668 0.796 rs213236 chr6:28324397 T/C cg13525197 chr6:28411240 ZSCAN23 -0.49 -4.68 -0.39 7.38e-6 Pubertal anthropometrics; TGCT cis rs2235649 0.551 rs1742454 chr16:1939378 G/T cg02432467 chr16:1963432 HS3ST6 -0.31 -4.89 -0.4 3.12e-6 Blood metabolite levels; TGCT trans rs7613875 0.578 rs2624822 chr3:50107219 T/C cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT cis rs2228479 0.867 rs76885005 chr16:89966668 A/G cg04013166 chr16:89971882 TCF25 0.33 4.64 0.38 8.86e-6 Skin colour saturation; TGCT cis rs6570726 0.791 rs446362 chr6:145878716 G/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs78487399 0.808 rs10180005 chr2:43737465 C/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1894292 0.527 rs1997332 chr4:74374174 C/T cg05868023 chr4:75230803 EREG -0.56 -5.05 -0.41 1.56e-6 Prostate cancer; TGCT cis rs3818285 0.679 rs612155 chr10:111630731 C/G cg00817464 chr10:111662876 XPNPEP1 0.32 5.7 0.46 8.35e-8 Superior crus of antihelix expression; TGCT cis rs478607 0.915 rs521793 chr11:64482947 G/C cg19395706 chr11:64412079 NRXN2 -0.47 -5.02 -0.41 1.73e-6 Urate levels; TGCT cis rs74233809 1.000 rs11191607 chr10:104959188 G/T cg05855489 chr10:104503620 C10orf26 0.82 4.7 0.39 6.66e-6 Birth weight; TGCT cis rs28386778 0.897 rs9913323 chr17:61851485 C/A cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs2115630 0.645 rs6496284 chr15:85178270 A/G cg17173187 chr15:85201210 NMB -0.46 -5.53 -0.44 1.82e-7 P wave terminal force; TGCT cis rs589448 0.967 rs634512 chr12:69754012 C/T cg20891283 chr12:69753455 YEATS4 0.91 10.33 0.68 1.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs2380220 0.510 rs9387562 chr6:96057006 G/T cg04719120 chr6:96025338 MANEA 0.74 5.55 0.45 1.67e-7 Behavioural disinhibition (generation interaction); TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg14820908 chr5:178986412 RUFY1 -0.59 -6.43 -0.5 2.52e-9 Lung cancer; TGCT cis rs12450688 1 rs12450688 chr17:38144229 G/A cg17467752 chr17:38218738 THRA -0.53 -5.33 -0.43 4.45e-7 Sum eosinophil basophil counts; TGCT cis rs7607369 0.618 rs62193298 chr2:219655211 T/G cg02176678 chr2:219576539 TTLL4 -0.47 -6.0 -0.47 2.02e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs6951245 0.935 rs78573577 chr7:1089087 C/A cg23708337 chr7:1209742 NA 0.56 5.08 0.42 1.34e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs853679 0.567 rs16894091 chr6:28390137 A/T cg18815343 chr6:28367644 ZSCAN12 0.5 4.61 0.38 9.72e-6 Depression; TGCT cis rs1801251 0.644 rs283473 chr2:233654847 A/G cg08000102 chr2:233561755 GIGYF2 0.61 6.89 0.53 2.54e-10 Coronary artery disease; TGCT cis rs1568889 0.667 rs16917914 chr11:28459909 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.66 5.48 0.44 2.3e-7 Bipolar disorder; TGCT cis rs4076764 0.958 rs6691127 chr1:163384831 T/C cg24596788 chr1:163392923 NA -0.17 -5.1 -0.42 1.23e-6 Motion sickness; TGCT cis rs12575480 0.672 rs74048171 chr11:2093603 C/A cg15541987 chr11:2077307 NA -0.37 -4.47 -0.37 1.71e-5 Pursuit maintenance gain; TGCT cis rs7119 0.623 rs11637932 chr15:77847353 T/G cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs9611565 0.592 rs4481089 chr22:41980892 T/C cg06481639 chr22:41940642 POLR3H -0.62 -5.26 -0.43 6.21e-7 Vitiligo; TGCT cis rs8177253 0.965 rs7638018 chr3:133495461 C/T cg08048268 chr3:133502702 NA 0.64 9.82 0.66 3.42e-17 Iron status biomarkers; TGCT trans rs1814175 0.817 rs28594987 chr11:50045181 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs9368481 0.761 rs3931464 chr6:26939856 C/A cg02458000 chr6:26745757 NA 0.52 4.61 0.38 9.87e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs12681288 0.676 rs1562921 chr8:1021986 G/T cg08872321 chr8:1308229 NA -0.24 -4.45 -0.37 1.86e-5 Schizophrenia; TGCT cis rs4862750 0.914 rs10027250 chr4:187873460 T/C cg10295955 chr4:187884368 NA -0.94 -13.14 -0.76 3.07e-25 Lobe attachment (rater-scored or self-reported); TGCT cis rs2070488 0.965 rs2284820 chr3:38562579 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT cis rs933688 0.759 rs1423593 chr5:90752351 T/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.99 8.63 0.61 2.51e-14 Smoking behavior; TGCT cis rs3617 0.625 rs2071042 chr3:52864584 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.77 -0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT trans rs80264589 1 rs80264589 chr6:26927602 G/A cg20516262 chr7:155325649 CNPY1 0.63 7.11 0.54 7.99e-11 Lung cancer;Intelligence (multi-trait analysis); TGCT cis rs4664308 0.806 rs4665162 chr2:161060184 A/G cg03641300 chr2:160917029 PLA2R1 -0.27 -6.83 -0.52 3.31e-10 Idiopathic membranous nephropathy; TGCT cis rs9467711 0.790 rs34107459 chr6:26328353 T/C cg16898833 chr6:26189333 HIST1H4D 1.27 5.72 0.46 7.64e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs854765 0.583 rs4925130 chr17:17807858 G/A cg09796270 chr17:17721594 SREBF1 0.23 4.57 0.38 1.14e-5 Total body bone mineral density; TGCT cis rs3806843 0.576 rs246017 chr5:140335060 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs6840360 0.608 rs6831644 chr4:152283746 A/G cg17479576 chr4:152424074 FAM160A1 -0.45 -4.72 -0.39 6.27e-6 Intelligence (multi-trait analysis); TGCT cis rs9322193 0.923 rs9689599 chr6:149953109 A/C cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs6951245 0.872 rs76161580 chr7:1100307 G/T cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1008375 0.933 rs10939757 chr4:17694125 T/C cg18681998 chr4:17616180 MED28 0.78 7.27 0.55 3.58e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4851254 0.660 rs1821830 chr2:100680279 C/T cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs7818382 1.000 rs7818382 chr8:96054000 C/T cg16049864 chr8:95962084 TP53INP1 -0.54 -5.91 -0.47 3.03e-8 Alzheimer's disease (late onset); TGCT cis rs7811142 0.943 rs67196635 chr7:100025564 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs3008870 1.000 rs2985825 chr1:67412822 T/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.91 0.73 2.83e-22 Lymphocyte percentage of white cells; TGCT cis rs4727027 0.899 rs6464942 chr7:148826368 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7666738 0.791 rs2865953 chr4:99040319 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs10504229 1.000 rs67236942 chr8:58176525 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10464366 0.746 rs6945547 chr7:39145389 C/G cg18850127 chr7:39170497 POU6F2 0.28 5.93 0.47 2.76e-8 IgG glycosylation; TGCT cis rs6543140 0.964 rs11886793 chr2:103072220 T/G cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs28595532 0.920 rs116799007 chr4:119763562 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs514406 0.505 rs269289 chr1:53167151 A/C cg24675658 chr1:53192096 ZYG11B -0.75 -8.4 -0.6 8.59e-14 Monocyte count; TGCT cis rs12477438 0.520 rs2632283 chr2:99776000 C/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs6964587 0.967 rs34040612 chr7:91798916 G/T cg22709100 chr7:91322751 NA 0.29 4.74 0.39 5.78e-6 Breast cancer; TGCT cis rs9926296 0.509 rs2159113 chr16:89832083 C/T cg04287289 chr16:89883240 FANCA 0.68 6.91 0.53 2.27e-10 Vitiligo; TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs8037137 0.915 rs3826033 chr15:91548601 G/A cg22570213 chr15:91497863 RCCD1 0.52 4.84 0.4 3.84e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs796364 0.806 rs203767 chr2:200902411 G/A cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs2204008 0.744 rs11181337 chr12:38322083 C/A cg26384229 chr12:38710491 ALG10B 0.77 6.85 0.52 3.04e-10 Bladder cancer; TGCT cis rs67311347 1.000 rs67680017 chr3:40533164 C/T cg02782426 chr3:40428986 ENTPD3 0.42 4.44 0.37 1.99e-5 Renal cell carcinoma; TGCT cis rs941408 1.000 rs1640274 chr19:2807375 G/A cg06609049 chr19:2785107 THOP1 0.79 6.52 0.51 1.61e-9 Total cholesterol levels; TGCT cis rs7586879 0.638 rs13035244 chr2:25134009 T/C cg01884057 chr2:25150051 NA 0.36 7.1 0.54 8.63e-11 Body mass index; TGCT cis rs6831352 0.918 rs2213035 chr4:100064233 G/A cg12011299 chr4:100065546 ADH4 -0.42 -4.98 -0.41 2.06e-6 Alcohol dependence; TGCT cis rs826838 0.967 rs11183577 chr12:38781887 A/G cg26384229 chr12:38710491 ALG10B 1.08 10.86 0.7 1.01e-19 Heart rate; TGCT cis rs2013441 1.000 rs2703810 chr17:20113715 C/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs1245541 0.934 rs921361 chr10:73867454 C/T cg09661010 chr10:73848153 SPOCK2 -0.38 -4.53 -0.38 1.34e-5 Insulin-like growth factors; TGCT cis rs3087591 0.960 rs4795593 chr17:29613600 G/C cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.43 -0.56 1.52e-11 Hip circumference; TGCT cis rs1843834 0.611 rs1058360 chr2:225449242 A/T cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs7100689 0.577 rs1340385 chr10:82058851 G/A cg01528321 chr10:82214614 TSPAN14 0.69 6.72 0.52 5.76e-10 Post bronchodilator FEV1; TGCT cis rs9300255 0.664 rs28372579 chr12:123881176 A/G cg00376283 chr12:123451042 ABCB9 -0.65 -4.58 -0.38 1.1e-5 Neutrophil percentage of white cells; TGCT cis rs2074585 0.839 rs11638780 chr15:91041896 G/T cg22089800 chr15:90895588 ZNF774 -0.76 -7.77 -0.57 2.55e-12 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs7615952 0.551 rs12695470 chr3:125635718 C/A cg05084668 chr3:125655381 ALG1L -0.63 -4.49 -0.37 1.58e-5 Blood pressure (smoking interaction); TGCT cis rs13191038 1 rs13191038 chr6:28482917 T/C cg10876282 chr6:28092338 ZSCAN16 0.86 4.47 0.37 1.72e-5 Urinary tract infection frequency; TGCT cis rs1577917 1.000 rs10455455 chr6:86670214 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.36 -0.43 3.86e-7 Response to antipsychotic treatment; TGCT cis rs263156 0.967 rs190522 chr6:142879060 T/A cg18419694 chr6:143832440 FUCA2 -0.38 -4.53 -0.38 1.36e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs6952808 0.792 rs12536261 chr7:1953571 G/A cg04267008 chr7:1944627 MAD1L1 -0.38 -5.12 -0.42 1.12e-6 Bipolar disorder and schizophrenia; TGCT cis rs9611519 0.857 rs4820434 chr22:41637119 G/T cg06634786 chr22:41940651 POLR3H -0.57 -5.21 -0.42 7.5e-7 Neuroticism; TGCT cis rs7572733 0.534 rs1518361 chr2:198812874 A/G cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs9560113 0.922 rs4773377 chr13:112174152 G/C cg14154082 chr13:112174009 NA 0.34 4.58 0.38 1.09e-5 Menarche (age at onset); TGCT cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg25703541 chr22:24373054 LOC391322 -0.82 -8.53 -0.61 4.22e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17601876 0.814 rs17523527 chr15:51554032 C/T cg19946085 chr15:51559439 CYP19A1 -0.32 -4.82 -0.4 4.06e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs4851266 0.966 rs13017207 chr2:100841235 G/A cg07810366 chr2:100720526 AFF3 -0.38 -5.43 -0.44 2.81e-7 Educational attainment; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg18538332 chr22:24372958 LOC391322 -0.87 -9.91 -0.66 2.08e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4819052 1.000 rs2297285 chr21:46705621 A/G cg06618935 chr21:46677482 NA 0.41 5.2 0.42 7.93e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6964587 1.000 rs6964587 chr7:91630620 G/T cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs2180341 0.781 rs7760652 chr6:127572096 A/G cg24812749 chr6:127587940 RNF146 0.79 6.6 0.51 1.09e-9 Breast cancer; TGCT cis rs1783925 1.000 rs1783925 chr11:125304009 C/T cg03464685 chr11:125439445 EI24 0.59 4.94 0.41 2.49e-6 Formal thought disorder in schizophrenia; TGCT cis rs7552404 1.000 rs11161510 chr1:76210289 A/G cg10523679 chr1:76189770 ACADM -0.91 -9.9 -0.66 2.26e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9926296 0.572 rs8047581 chr16:89884502 C/T cg27121462 chr16:89883253 FANCA 0.59 5.77 0.46 6.09e-8 Vitiligo; TGCT cis rs72781680 0.716 rs2712068 chr2:23984000 A/G cg08917208 chr2:24149416 ATAD2B 0.75 5.04 0.41 1.59e-6 Lymphocyte counts; TGCT cis rs950169 0.881 rs4081123 chr15:84956235 A/G cg17173187 chr15:85201210 NMB 0.58 5.93 0.47 2.77e-8 Schizophrenia; TGCT cis rs2730245 0.505 rs1188956 chr7:158690576 G/A cg24397884 chr7:158709396 WDR60 0.39 5.1 0.42 1.23e-6 Height; TGCT cis rs13082711 0.522 rs569960 chr3:27329540 C/T cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg20637647 chr7:64974828 NA -0.92 -5.09 -0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs7582180 0.614 rs4149518 chr2:101013649 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 6.02e-6 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.588 rs9883000 chr3:49667691 A/G cg05785598 chr3:49045655 WDR6 0.39 4.67 0.39 7.55e-6 Menarche (age at onset); TGCT cis rs5769765 0.658 rs2157536 chr22:50190180 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -0.94 -8.64 -0.61 2.38e-14 Schizophrenia; TGCT cis rs739496 0.615 rs649406 chr12:112126065 T/C cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs7267979 0.966 rs2387885 chr20:25415224 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9427116 0.502 rs9426827 chr1:154589965 T/C cg17218026 chr1:154582156 ADAR 0.31 7.97 0.58 8.71e-13 Blood protein levels; TGCT cis rs682748 0.846 rs12657901 chr5:17162704 A/G cg23987134 chr5:17158319 LOC285696 -0.22 -5.37 -0.43 3.82e-7 Hippocampal atrophy; TGCT cis rs7824557 0.628 rs7820301 chr8:11228672 G/A cg21775007 chr8:11205619 TDH 0.74 7.49 0.56 1.1e-11 Retinal vascular caliber; TGCT cis rs4819052 0.851 rs35560973 chr21:46662573 T/C cg06618935 chr21:46677482 NA -0.34 -5.32 -0.43 4.78e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs933688 0.938 rs12110065 chr5:90718474 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.17 0.59 3.05e-13 Smoking behavior; TGCT cis rs9295536 0.620 rs6901879 chr6:22137547 T/C cg25792714 chr6:21666554 FLJ22536 -0.54 -4.87 -0.4 3.29e-6 Neuroblastoma; TGCT cis rs7267979 0.549 rs11698185 chr20:25181998 T/C cg14121845 chr20:25566513 NINL 0.42 4.45 0.37 1.85e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6952808 1.000 rs6954521 chr7:1886865 C/A cg22963979 chr7:1858916 MAD1L1 -0.36 -5.62 -0.45 1.21e-7 Bipolar disorder and schizophrenia; TGCT cis rs2032447 0.670 rs198801 chr6:26139741 T/C cg03264133 chr6:25882463 NA 0.5 4.53 0.38 1.39e-5 Intelligence (multi-trait analysis); TGCT cis rs933688 1.000 rs12654787 chr5:90713259 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.35 0.6 1.17e-13 Smoking behavior; TGCT cis rs66573146 0.831 rs67665838 chr4:7064870 G/A cg02503808 chr4:7069936 GRPEL1 -0.88 -4.54 -0.38 1.31e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2797160 0.651 rs1268067 chr6:126036621 T/C cg05901451 chr6:126070800 HEY2 0.75 6.71 0.52 6.16e-10 Endometrial cancer; TGCT cis rs2677744 0.626 rs2001216 chr15:91498130 T/C cg22570213 chr15:91497863 RCCD1 0.38 4.61 0.38 9.98e-6 Attention deficit hyperactivity disorder; TGCT cis rs56104184 0.775 rs73061695 chr19:49399988 T/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs36051895 0.659 rs1575285 chr9:5267440 A/G cg02405213 chr9:5042618 JAK2 -0.61 -7.53 -0.56 9.03e-12 Pediatric autoimmune diseases; TGCT cis rs9467773 1.000 rs767471 chr6:26557854 C/T cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs7100689 0.646 rs6585967 chr10:82139791 A/G cg01528321 chr10:82214614 TSPAN14 -0.81 -8.55 -0.61 3.8e-14 Post bronchodilator FEV1; TGCT cis rs4808199 1.000 rs17288409 chr19:19504167 T/C cg03709012 chr19:19516395 GATAD2A 0.97 7.52 0.56 9.52e-12 Nonalcoholic fatty liver disease; TGCT cis rs35306767 0.761 rs11253559 chr10:1044809 T/C cg18964960 chr10:1102726 WDR37 0.78 5.46 0.44 2.45e-7 Eosinophil percentage of granulocytes; TGCT cis rs11122272 0.735 rs2739513 chr1:231515201 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -6.96 -0.53 1.78e-10 Hemoglobin concentration; TGCT cis rs7474896 0.609 rs11011336 chr10:37985316 A/G cg25427524 chr10:38739819 LOC399744 -0.31 -4.86 -0.4 3.52e-6 Obesity (extreme); TGCT cis rs10789491 1.000 rs7547522 chr1:47179918 C/G cg15501359 chr1:47185051 KIAA0494 0.81 8.34 0.6 1.19e-13 Response to hepatitis C treatment; TGCT cis rs13191362 0.688 rs73035006 chr6:162997083 G/T cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9611565 0.512 rs9607842 chr22:42192722 G/A cg13695892 chr22:41940480 POLR3H -0.83 -7.85 -0.58 1.69e-12 Vitiligo; TGCT cis rs6840360 0.550 rs62327267 chr4:152518753 G/T cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs6952809 0.532 rs6953297 chr7:2440874 C/G cg23289794 chr7:2394357 EIF3B -0.83 -7.0 -0.53 1.44e-10 Multiple sclerosis; TGCT cis rs9296092 0.517 rs62405895 chr6:33471969 G/T cg13560919 chr6:33536144 NA -0.22 -4.49 -0.37 1.6e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7824557 0.606 rs1047950 chr8:11185096 G/C cg21775007 chr8:11205619 TDH 0.69 6.62 0.51 9.52e-10 Retinal vascular caliber; TGCT cis rs66573146 0.831 rs56081162 chr4:6989718 C/T cg05069807 chr4:6945702 TBC1D14 0.31 4.83 0.4 3.91e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs8180040 0.932 rs62248599 chr3:47516728 G/A cg27129171 chr3:47204927 SETD2 -0.65 -7.68 -0.57 4.2e-12 Colorectal cancer; TGCT cis rs28595532 0.748 rs72670249 chr4:119336823 G/T cg11846333 chr4:119757529 SEC24D 0.72 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs832540 0.656 rs2408597 chr5:56098632 G/A cg24531977 chr5:56204891 C5orf35 -0.51 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs17345786 0.798 rs9817043 chr3:101281852 A/G cg11279151 chr3:101281821 RG9MTD1 -0.45 -10.63 -0.69 3.76e-19 Colonoscopy-negative controls vs population controls; TGCT cis rs13177918 0.677 rs13161156 chr5:149822586 A/G cg14059543 chr5:149831962 NA -0.71 -9.46 -0.65 2.58e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2354432 0.556 rs57388899 chr1:146773422 T/C cg25205988 chr1:146714368 CHD1L -1.18 -7.03 -0.53 1.24e-10 Mitochondrial DNA levels; TGCT cis rs4242434 0.927 rs720746 chr8:22471399 T/C cg21658235 chr8:22456391 C8orf58 0.43 4.5 0.37 1.54e-5 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs881375 0.678 rs10760130 chr9:123701990 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.93 0.4 2.56e-6 Rheumatoid arthritis; TGCT cis rs10510102 0.872 rs12246728 chr10:123726133 C/T cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT trans rs11250098 0.583 rs36030755 chr8:10816771 G/C cg06636001 chr8:8085503 FLJ10661 -0.78 -6.96 -0.53 1.77e-10 Morning vs. evening chronotype; TGCT cis rs79349575 0.783 rs12603969 chr17:47034419 A/G cg26022315 chr17:47021804 SNF8 0.47 4.61 0.38 9.94e-6 Type 2 diabetes; TGCT cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg13695892 chr22:41940480 POLR3H -0.92 -9.33 -0.64 5.22e-16 Vitiligo; TGCT cis rs2933343 0.679 rs789229 chr3:128602526 C/T cg11901034 chr3:128598214 ACAD9 -0.68 -6.63 -0.51 9.16e-10 IgG glycosylation; TGCT cis rs7953249 0.618 rs7954331 chr12:121398657 G/T cg02403541 chr12:121454288 C12orf43 -0.65 -5.5 -0.44 2.07e-7 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs28595532 0.841 rs115987912 chr4:119737085 C/T cg21605333 chr4:119757512 SEC24D 1.61 8.95 0.63 4.36e-15 Cannabis dependence symptom count; TGCT cis rs6951245 0.554 rs11544331 chr7:1131411 C/T cg09177884 chr7:1199841 ZFAND2A -0.72 -5.71 -0.46 7.86e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4663866 0.901 rs34040298 chr2:239191607 T/C cg17283117 chr2:239148619 HES6 1.01 4.66 0.39 8.09e-6 Irritable bowel syndrome; TGCT cis rs4372836 0.505 rs6710082 chr2:28989977 A/C cg09522027 chr2:28974177 PPP1CB -0.73 -7.07 -0.54 9.78e-11 Body mass index; TGCT cis rs78487399 0.808 rs7556744 chr2:43672795 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 -0.72 -4.62 -0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg05457628 chr5:178986728 RUFY1 0.53 5.85 0.47 4.03e-8 Lung cancer; TGCT cis rs981844 0.848 rs72731652 chr4:154641123 A/T cg14289246 chr4:154710475 SFRP2 1.01 8.19 0.59 2.76e-13 Response to statins (LDL cholesterol change); TGCT cis rs9486719 0.947 rs2499801 chr6:96854594 G/A cg06623918 chr6:96969491 KIAA0776 0.98 8.23 0.59 2.13e-13 Migraine;Coronary artery disease; TGCT cis rs11122272 0.735 rs2250719 chr1:231486208 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.88 -0.53 2.66e-10 Hemoglobin concentration; TGCT cis rs896854 0.654 rs6982393 chr8:95980708 T/C cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs75686122 0.892 rs17805990 chr8:104534025 T/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs926938 0.618 rs360617 chr1:115404099 G/A cg12756093 chr1:115239321 AMPD1 0.4 5.91 0.47 3.1e-8 Autism; TGCT cis rs2303745 0.589 rs751599 chr19:17396549 A/G cg02221750 chr19:17393354 ANKLE1 -0.48 -6.23 -0.49 6.76e-9 Systemic lupus erythematosus; TGCT trans rs10435719 0.899 rs11250177 chr8:11799099 G/A cg15556689 chr8:8085844 FLJ10661 0.75 7.07 0.54 9.74e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs644148 0.785 rs117048220 chr19:44965555 G/A cg15540054 chr19:45004280 ZNF180 0.59 5.34 0.43 4.35e-7 Personality dimensions; TGCT cis rs2486288 0.656 rs2413772 chr15:45549862 G/A cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.45 -0.56 1.41e-11 Glomerular filtration rate; TGCT trans rs28735056 0.875 rs4239346 chr18:77641226 A/G cg05926928 chr17:57297772 GDPD1 0.68 7.27 0.55 3.61e-11 Schizophrenia; TGCT cis rs17221829 0.645 rs4753227 chr11:89369102 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs782590 0.967 rs4290693 chr2:55799991 C/G cg03859395 chr2:55845619 SMEK2 0.91 11.18 0.71 1.71e-20 Metabolic syndrome; TGCT cis rs739496 0.947 rs28362508 chr12:111884415 T/C cg10833066 chr12:111807467 FAM109A 0.35 4.75 0.39 5.49e-6 Platelet count; TGCT trans rs7613875 0.600 rs2624826 chr3:50155468 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.82 -8.52 -0.61 4.53e-14 Body mass index; TGCT cis rs9810089 0.802 rs833861 chr3:136231067 T/A cg12473912 chr3:136751656 NA 0.33 4.79 0.4 4.64e-6 Gestational age at birth (child effect); TGCT cis rs17221829 0.589 rs7930747 chr11:89377160 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs17384381 1.000 rs12758768 chr1:85835206 C/T cg16011679 chr1:85725395 C1orf52 0.86 6.78 0.52 4.3e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs60154123 0.730 rs11119455 chr1:210457762 C/T cg22029157 chr1:209979665 IRF6 0.6 4.46 0.37 1.81e-5 Coronary artery disease; TGCT cis rs1552244 0.572 rs6785976 chr3:10168647 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.85 5.14 0.42 1.04e-6 Alzheimer's disease; TGCT cis rs9443645 0.901 rs10943612 chr6:79698380 C/T cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs13124904 chr4:98856973 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs71435601 0.628 rs529697 chr2:21387948 G/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs861020 0.563 rs12046618 chr1:210043135 C/T cg05527609 chr1:210001259 C1orf107 0.94 7.34 0.55 2.5e-11 Orofacial clefts; TGCT cis rs6121246 0.559 rs6119650 chr20:30258480 C/A cg13852791 chr20:30311386 BCL2L1 0.81 7.61 0.56 5.85e-12 Mean corpuscular hemoglobin; TGCT cis rs259282 0.602 rs194589 chr19:33144621 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.81 7.96 0.58 9.26e-13 Schizophrenia; TGCT cis rs79349575 0.811 rs1057897 chr17:47005509 T/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs1371867 0.846 rs1660317 chr8:101333252 G/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs9473924 0.954 rs9463653 chr6:50835180 A/G cg14470998 chr6:50812995 TFAP2B 0.61 4.48 0.37 1.7e-5 Body mass index; TGCT cis rs6840360 0.571 rs11726892 chr4:152555106 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs6089829 0.851 rs10854168 chr20:61669550 A/G cg03213289 chr20:61660250 NA 0.72 9.45 0.65 2.69e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg05368731 chr17:41323189 NBR1 1.05 11.93 0.73 2.59e-22 Menopause (age at onset); TGCT cis rs4819052 0.851 rs8134392 chr21:46663790 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 -0.6 -4.9 -0.4 2.93e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11190604 1.000 rs2495754 chr10:102324812 C/T cg16342193 chr10:102329863 NA -0.4 -5.08 -0.42 1.32e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1472147 1.000 rs4323418 chr7:128506970 C/T cg00260937 chr7:128520193 KCP -0.39 -6.01 -0.47 1.92e-8 Calcium levels; TGCT cis rs12049351 0.774 rs12039754 chr1:229644896 G/A cg12130225 chr1:229698885 NA 0.38 4.46 0.37 1.82e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs854765 0.547 rs2955380 chr17:17944349 A/G cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.87e-6 Total body bone mineral density; TGCT cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg16049864 chr8:95962084 TP53INP1 -0.7 -9.94 -0.67 1.76e-17 Type 2 diabetes; TGCT cis rs909674 0.541 rs5757655 chr22:39797178 C/G cg01416388 chr22:39784598 NA 0.72 7.4 0.55 1.78e-11 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2832191 0.716 rs2297252 chr21:30377104 G/A cg24692254 chr21:30365293 RNF160 0.97 11.36 0.71 6.01e-21 Dental caries; TGCT cis rs7267979 0.844 rs6050477 chr20:25221547 C/T cg21995068 chr20:25989032 LOC100134868 0.39 4.81 0.4 4.35e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs610932 0.517 rs668287 chr11:59974629 G/T cg18570331 chr11:60101691 MS4A6E 0.52 4.84 0.4 3.79e-6 Alzheimer's disease; TGCT cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg12756686 chr19:29218302 NA 0.76 6.52 0.51 1.6e-9 Methadone dose in opioid dependence; TGCT cis rs2456568 0.802 rs10765640 chr11:93636462 C/T cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.07e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3617 0.573 rs62253582 chr3:52928333 G/A cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.67 0.39 7.65e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4494114 1.000 rs4388668 chr1:39360730 A/T cg25970120 chr1:39325951 RRAGC -0.6 -6.32 -0.49 4.21e-9 Blood protein levels; TGCT cis rs25422 0.887 rs9481844 chr6:118990941 G/A cg07617317 chr6:118971624 C6orf204 0.44 4.7 0.39 6.74e-6 Renal cell carcinoma; TGCT cis rs74233809 1.000 rs11191514 chr10:104773364 C/T cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs2639990 1.000 rs2639990 chr18:72915551 T/C cg18449964 chr18:72917101 ZADH2 0.94 6.32 0.49 4.19e-9 Vascular endothelial growth factor levels; TGCT cis rs36051895 0.632 rs1360063 chr9:5167649 A/G cg02405213 chr9:5042618 JAK2 -0.72 -9.42 -0.65 3.18e-16 Pediatric autoimmune diseases; TGCT cis rs9914544 0.689 rs1634423 chr17:18844736 C/T cg26306683 chr17:18585705 ZNF286B 0.56 5.23 0.42 7.08e-7 Educational attainment (years of education); TGCT cis rs3784262 0.757 rs74655564 chr15:58325512 G/C cg12031962 chr15:58353849 ALDH1A2 -0.58 -8.99 -0.63 3.42e-15 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs6740731 0.518 rs34586719 chr2:145295647 C/T cg19463199 chr3:197401858 MIR922;KIAA0226 0.38 6.77 0.52 4.64e-10 Coronary artery disease; TGCT cis rs7098414 0.511 rs12262228 chr10:82160425 C/T cg00277334 chr10:82204260 NA -0.38 -4.98 -0.41 2.08e-6 Post bronchodilator FEV1; TGCT cis rs2242116 0.796 rs2290546 chr3:46965197 C/G cg27129171 chr3:47204927 SETD2 0.66 6.34 0.49 3.88e-9 Birth weight; TGCT cis rs769267 0.965 rs735273 chr19:19385411 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs3820068 0.705 rs74054769 chr1:15860147 A/C cg05660106 chr1:15850417 CASP9 1.15 13.74 0.78 1.14e-26 Systolic blood pressure; TGCT cis rs4664308 0.935 rs17216980 chr2:160960932 G/A cg03641300 chr2:160917029 PLA2R1 -0.28 -6.88 -0.53 2.57e-10 Idiopathic membranous nephropathy; TGCT cis rs3799378 0.579 rs9348715 chr6:26375642 C/G cg05738196 chr6:26577821 NA -0.53 -5.05 -0.41 1.55e-6 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.501 rs13000731 chr2:99795231 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs807669 0.772 rs809901 chr22:19228736 C/T cg02655711 chr22:19163373 SLC25A1 0.34 7.43 0.55 1.58e-11 Metabolite levels; TGCT cis rs4595586 0.545 rs6580888 chr12:39369704 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs1018836 0.923 rs13262354 chr8:91635731 G/A cg16814680 chr8:91681699 NA -0.91 -9.92 -0.67 1.98e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs11514810 1.000 rs9648620 chr7:1427980 T/C cg24899294 chr7:1481343 MICALL2 -0.41 -5.69 -0.46 8.5e-8 Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder; TGCT cis rs9611565 0.649 rs6002480 chr22:42176917 A/T cg06634786 chr22:41940651 POLR3H -0.77 -7.17 -0.54 6.02e-11 Vitiligo; TGCT cis rs4704846 1.000 rs6555849 chr5:156529647 A/G cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs7845219 0.539 rs713113 chr8:95877787 C/T cg16049864 chr8:95962084 TP53INP1 0.54 6.17 0.48 8.74e-9 Type 2 diabetes; TGCT cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs28595532 1.000 rs75497896 chr4:119636703 T/C cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.12e-11 Cannabis dependence symptom count; TGCT cis rs4665809 1.000 rs2384321 chr2:26290054 A/G cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs514406 0.621 rs928452 chr1:53195926 G/C cg16325326 chr1:53192061 ZYG11B -0.89 -13.12 -0.76 3.31e-25 Monocyte count; TGCT cis rs9372498 0.536 rs9320660 chr6:118956827 A/T cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs10504229 1.000 rs77857677 chr8:58170131 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs752092 0.894 rs8036083 chr15:101767822 T/G cg19997662 chr15:101784653 CHSY1 -0.27 -4.85 -0.4 3.62e-6 Corneal structure; TGCT cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg17554472 chr22:41940697 POLR3H 0.47 4.89 0.4 3.06e-6 Vitiligo; TGCT cis rs9650657 0.504 rs10108347 chr8:11033517 G/C cg21775007 chr8:11205619 TDH -0.49 -4.56 -0.38 1.19e-5 Neuroticism; TGCT cis rs763014 0.833 rs916415 chr16:632115 G/A cg09263875 chr16:632152 PIGQ 0.3 6.4 0.5 2.88e-9 Height; TGCT cis rs12935418 0.616 rs62054239 chr16:81000184 G/T cg07676361 chr16:80966860 NA -0.35 -4.56 -0.38 1.19e-5 Mean corpuscular volume; TGCT cis rs1577917 0.958 rs34994386 chr6:86524135 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.21 -0.42 7.64e-7 Response to antipsychotic treatment; TGCT cis rs7829975 0.624 rs7823056 chr8:8382705 A/G cg15556689 chr8:8085844 FLJ10661 0.74 7.02 0.53 1.27e-10 Mood instability; TGCT cis rs910316 1.000 rs12879542 chr14:75507525 C/T cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.36e-19 Height; TGCT cis rs854765 0.624 rs11657423 chr17:17728574 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.71 -0.52 6.32e-10 Total body bone mineral density; TGCT cis rs5769765 0.955 rs7511159 chr22:50307896 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.52 0.44 1.93e-7 Schizophrenia; TGCT cis rs3731896 0.706 rs11886864 chr2:220156531 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.71 4.45 0.37 1.87e-5 Educational attainment; TGCT trans rs1005277 0.522 rs289645 chr10:37943642 T/C cg17830980 chr10:43048298 ZNF37B -0.65 -6.94 -0.53 1.96e-10 Extrinsic epigenetic age acceleration; TGCT cis rs9611565 0.512 rs6519289 chr22:42170432 A/C cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs13326165 0.760 rs34523877 chr3:52375711 T/C cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7605378 1.000 rs769957 chr2:200695524 A/C cg23649088 chr2:200775458 C2orf69 0.34 5.53 0.44 1.84e-7 Osteoporosis; TGCT cis rs9859260 0.744 rs3933 chr3:195784997 C/T cg22891161 chr3:195456627 MUC20 0.23 4.64 0.38 8.64e-6 Mean corpuscular volume; TGCT cis rs13191362 0.507 rs2803051 chr6:163034979 G/A cg21926612 chr6:163149169 PACRG;PARK2 -0.61 -5.85 -0.46 4.17e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12188164 1.000 rs12188164 chr5:428236 C/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.41 -4.77 -0.39 5.03e-6 Cystic fibrosis severity; TGCT cis rs2455799 0.634 rs1584326 chr3:15903951 G/A cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.68e-6 Mean platelet volume; TGCT cis rs2404602 0.647 rs11072616 chr15:76985269 T/C cg23625390 chr15:77176239 SCAPER -0.37 -4.73 -0.39 5.88e-6 Blood metabolite levels; TGCT cis rs524281 0.861 rs10896081 chr11:65880354 A/T cg00563793 chr11:65837595 PACS1 0.53 4.58 0.38 1.12e-5 Electroencephalogram traits; TGCT cis rs394563 0.591 rs11964335 chr6:149658101 A/T cg03678062 chr6:149772716 ZC3H12D 0.38 4.83 0.4 3.94e-6 Dupuytren's disease; TGCT cis rs17433780 0.897 rs12142922 chr1:89489915 A/G cg09516651 chr1:89888402 LOC400759 0.26 4.48 0.37 1.67e-5 Carotid intima media thickness; TGCT cis rs9733 0.519 rs72704603 chr1:150707992 C/T cg04414720 chr1:150670196 GOLPH3L 0.38 5.0 0.41 1.88e-6 Tonsillectomy; TGCT cis rs8064299 0.934 rs895692 chr17:72766252 G/A cg25054828 chr17:72772726 NAT9;TMEM104 0.78 7.84 0.58 1.77e-12 Monocyte count; TGCT cis rs2180341 0.855 rs4308584 chr6:127714874 A/G cg24812749 chr6:127587940 RNF146 0.79 6.49 0.5 1.9e-9 Breast cancer; TGCT cis rs7772486 0.720 rs702320 chr6:146006654 G/A cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs736408 0.608 rs4687657 chr3:52852538 G/T cg10802521 chr3:52805072 NEK4 -0.64 -6.51 -0.5 1.69e-9 Bipolar disorder; TGCT trans rs877282 0.853 rs10904545 chr10:757100 G/A cg22713356 chr15:30763199 NA 1.13 8.3 0.6 1.52e-13 Uric acid levels; TGCT cis rs3774830 0.743 rs11728680 chr4:5462247 A/G cg26943120 chr4:5472116 STK32B 0.23 5.16 0.42 9.66e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs1865760 0.865 rs4478388 chr6:25953633 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.31 0.49 4.56e-9 Height; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.51 5.23 0.42 7.05e-7 Lymphocyte counts; TGCT cis rs9435341 0.965 rs3108680 chr1:107572997 T/C cg09367891 chr1:107599246 PRMT6 0.64 5.6 0.45 1.29e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs1113500 0.814 rs12039712 chr1:108641199 A/G cg22161131 chr1:109420278 GPSM2 0.5 4.6 0.38 1.04e-5 Growth-regulated protein alpha levels; TGCT cis rs617219 0.596 rs2131977 chr5:78613916 G/C cg23987322 chr5:78407566 BHMT -0.36 -4.69 -0.39 7.01e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs782590 0.620 rs7596377 chr2:55888612 T/A cg03859395 chr2:55845619 SMEK2 -0.75 -6.87 -0.52 2.78e-10 Metabolic syndrome; TGCT cis rs9916302 0.904 rs6503506 chr17:37524653 C/A cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs7949030 0.626 rs7930896 chr11:62325272 A/G cg11742103 chr11:62369870 EML3;MTA2 0.6 8.46 0.6 6.37e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs951366 0.903 rs708723 chr1:205739266 C/T cg17178900 chr1:205818956 PM20D1 0.42 4.7 0.39 6.72e-6 Menarche (age at onset); TGCT cis rs644799 0.965 rs10831426 chr11:95505888 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.46 0.6 6.27e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7772486 0.692 rs1577916 chr6:146069789 G/A cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.545 rs3167757 chr21:40714478 C/T cg17971929 chr21:40555470 PSMG1 0.6 5.51 0.44 1.97e-7 Cognitive function; TGCT cis rs988712 0.516 rs6484320 chr11:27703188 T/A cg10635145 chr11:27742435 BDNF 0.43 6.14 0.48 1.04e-8 Obesity; TGCT cis rs6582630 0.519 rs10880194 chr12:38302836 G/A cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.3e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs1008375 0.932 rs4698629 chr4:17608884 C/G cg18681998 chr4:17616180 MED28 0.73 4.95 0.41 2.4e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6988636 0.710 rs62521805 chr8:124159200 C/T cg27053337 chr8:124217698 FAM83A 0.67 5.12 0.42 1.11e-6 Urinary uromodulin levels; TGCT cis rs10791097 0.765 rs7943757 chr11:130716157 C/T cg12179176 chr11:130786555 SNX19 0.63 6.55 0.51 1.39e-9 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs57590327 0.504 rs4856348 chr3:81502923 T/G cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs9611565 0.921 rs8137373 chr22:41729216 A/G cg13695892 chr22:41940480 POLR3H 0.76 7.25 0.55 3.83e-11 Vitiligo; TGCT cis rs28595532 0.844 rs115573749 chr4:119756848 T/A cg14228332 chr4:119757509 SEC24D 1.29 6.0 0.47 1.98e-8 Cannabis dependence symptom count; TGCT cis rs10893109 0.934 rs7130744 chr11:123801600 A/C cg14126608 chr11:122846540 NA -0.3 -4.51 -0.38 1.46e-5 Facial morphology (factor 13, vertical position of alar curvature relative to upper lip); TGCT cis rs11105298 0.891 rs10858869 chr12:89857611 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6951245 1.000 rs111899361 chr7:1112348 C/T cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17401966 0.809 rs12406943 chr1:10308545 T/C cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs7666738 0.753 rs2865957 chr4:99040725 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9394169 0.514 rs1886355 chr6:33776877 C/T cg00334056 chr6:33755658 LEMD2 -0.24 -4.55 -0.38 1.28e-5 Essential tremor; TGCT cis rs9913156 0.793 rs55782417 chr17:4562845 G/A cg19197139 chr17:4613644 ARRB2 0.86 7.9 0.58 1.32e-12 Lymphocyte counts; TGCT cis rs7513165 0.935 rs4951319 chr1:204162230 A/G cg04791601 chr1:204159016 NA 0.24 5.02 0.41 1.77e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs1670533 1.000 rs1670534 chr4:1087265 T/C cg27284194 chr4:1044797 NA 0.68 5.95 0.47 2.59e-8 Recombination rate (females); TGCT cis rs6964587 0.967 rs12538325 chr7:91757479 A/G cg22709100 chr7:91322751 NA 0.28 4.58 0.38 1.1e-5 Breast cancer; TGCT cis rs2721811 0.738 rs1544366 chr7:24758248 A/G cg17569154 chr7:24781545 DFNA5 0.21 4.54 0.38 1.32e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9646954 0.542 rs4149513 chr2:101022726 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 5.95e-6 Intelligence (multi-trait analysis); TGCT cis rs727505 0.954 rs2170352 chr7:124605584 G/A cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs6693567 0.507 rs9436120 chr1:150473084 T/C cg09579323 chr1:150459698 TARS2 0.53 4.63 0.38 9.01e-6 Migraine; TGCT cis rs9811920 0.535 rs1610509 chr3:99474327 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.38 -4.63 -0.38 9.01e-6 Axial length; TGCT cis rs6089829 0.925 rs3746748 chr20:61667526 C/T cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs2836974 0.897 rs35391055 chr21:40525516 G/A cg11644478 chr21:40555479 PSMG1 1.02 10.86 0.7 1.05e-19 Cognitive function; TGCT cis rs611744 0.647 rs628206 chr8:109247873 A/G cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs7726839 0.540 rs12520279 chr5:657291 T/C cg16624210 chr5:671434 TPPP 0.41 4.6 0.38 1.02e-5 Obesity-related traits; TGCT cis rs1862618 0.671 rs2255726 chr5:56243128 T/C cg20203395 chr5:56204925 C5orf35 0.51 4.73 0.39 5.91e-6 Initial pursuit acceleration; TGCT cis rs7439150 0.954 rs2059502 chr4:155493319 C/T cg22130008 chr4:155548532 NA 0.5 6.14 0.48 1.05e-8 Fibrinogen levels; TGCT cis rs2404602 0.655 rs34748201 chr15:77221530 G/T cg22467129 chr15:76604101 ETFA -0.5 -5.65 -0.45 1.06e-7 Blood metabolite levels; TGCT cis rs7267979 1.000 rs4815411 chr20:25350223 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6674176 0.935 rs4314918 chr1:44377503 G/A cg13606994 chr1:44402422 ARTN -0.46 -4.71 -0.39 6.45e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7666738 0.830 rs13149346 chr4:99009933 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs12950390 0.893 rs4794110 chr17:45847230 A/G cg24803719 chr17:45855879 NA -0.41 -4.55 -0.38 1.25e-5 IgG glycosylation; TGCT cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg23719950 chr11:63933701 MACROD1 -0.72 -5.97 -0.47 2.28e-8 Mean platelet volume; TGCT cis rs7089973 0.872 rs10490908 chr10:116616162 T/C cg03647239 chr10:116582469 FAM160B1 0.52 4.64 0.38 8.75e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7091068 0.615 rs11187609 chr10:95467031 A/C cg20715218 chr10:95462985 C10orf4 0.51 4.94 0.41 2.45e-6 Urinary tract infection frequency; TGCT cis rs17376456 0.877 rs9314101 chr5:93461593 A/T cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs2439831 0.681 rs524527 chr15:43599116 C/G cg02155558 chr15:43621948 ADAL;LCMT2 -1.08 -8.94 -0.63 4.46e-15 Lung cancer in ever smokers; TGCT cis rs6684514 0.506 rs3762281 chr1:156304782 A/G cg16558208 chr1:156270281 VHLL 0.27 4.89 0.4 3.06e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7513165 0.611 rs34729972 chr1:204159178 A/G cg04791601 chr1:204159016 NA 0.24 4.43 0.37 2.01e-5 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs10782582 0.593 rs11163967 chr1:76154185 T/C cg22875332 chr1:76189707 ACADM -0.55 -6.35 -0.5 3.77e-9 Daytime sleep phenotypes; TGCT cis rs1046896 0.514 rs9894705 chr17:80823758 A/C cg03160526 chr17:80928410 B3GNTL1 -0.33 -4.59 -0.38 1.07e-5 Glycated hemoglobin levels; TGCT cis rs7714584 1.000 rs6862814 chr5:150245259 G/A cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs7020830 0.931 rs7034554 chr9:37081301 A/G cg14235030 chr9:37121269 ZCCHC7 0.4 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs6867032 0.958 rs4505990 chr5:2015811 A/G cg26168224 chr5:2018326 NA 0.43 7.96 0.58 9.31e-13 Gut microbiome composition (winter); TGCT cis rs4819052 0.885 rs9980676 chr21:46665430 A/G cg06618935 chr21:46677482 NA -0.37 -5.64 -0.45 1.1e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2153535 0.541 rs9505456 chr6:8479001 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2243480 1.000 rs313802 chr7:65516373 A/G cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs10876993 0.890 rs1082502 chr12:58035706 C/T cg15848620 chr12:58087721 OS9 -0.72 -5.86 -0.47 3.87e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7586879 0.559 rs13387729 chr2:25076126 A/G cg01884057 chr2:25150051 NA 0.3 5.61 0.45 1.26e-7 Body mass index; TGCT cis rs3741404 0.895 rs1860368 chr11:63994692 T/C cg03236948 chr11:63997492 DNAJC4 -0.39 -4.93 -0.4 2.6e-6 Platelet count; TGCT cis rs4383453 0.539 rs56276445 chr3:123098242 C/A cg04890266 chr3:123102914 ADCY5 -0.5 -8.3 -0.6 1.48e-13 Gestational age at birth (maternal effect); TGCT cis rs9913156 0.707 rs9902000 chr17:4582426 A/C cg19197139 chr17:4613644 ARRB2 -0.82 -7.88 -0.58 1.42e-12 Lymphocyte counts; TGCT cis rs8179 0.593 rs73232024 chr7:92277315 G/A cg15732164 chr7:92237376 CDK6 -0.29 -5.06 -0.41 1.46e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs7224685 0.569 rs8066580 chr17:3996494 T/C cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs12711979 0.513 rs7566217 chr2:3851381 A/C cg17052675 chr2:3827356 NA -0.26 -4.48 -0.37 1.7e-5 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs478304 0.934 rs603645 chr11:65533000 A/C cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.01e-7 Acne (severe); TGCT cis rs7107174 0.688 rs10899501 chr11:78131408 C/T cg12700464 chr11:78128424 GAB2 -0.67 -4.46 -0.37 1.83e-5 Testicular germ cell tumor; TGCT cis rs6964587 0.967 rs10231350 chr7:91808499 G/T cg22709100 chr7:91322751 NA 0.29 4.69 0.39 7.08e-6 Breast cancer; TGCT cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg07507251 chr3:52567010 NT5DC2 0.47 6.95 0.53 1.88e-10 Bipolar disorder; TGCT cis rs3008870 0.959 rs3008852 chr1:67383416 G/A cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.08 0.74 1.11e-22 Lymphocyte percentage of white cells; TGCT cis rs769267 1.000 rs7246748 chr19:19433105 C/T cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs76878669 0.515 rs12576299 chr11:66132286 T/C cg18002602 chr11:66138449 SLC29A2 0.54 6.62 0.51 9.76e-10 Educational attainment (years of education); TGCT cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs4478858 0.735 rs4494186 chr1:31857847 G/A cg00250761 chr1:31883323 NA 0.24 4.45 0.37 1.91e-5 Alcohol dependence; TGCT cis rs9640161 0.750 rs17173617 chr7:150038023 G/C cg17279839 chr7:150038598 RARRES2 0.45 4.91 0.4 2.83e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs4917300 0.743 rs34292923 chr8:143094726 G/C cg08115556 chr8:142137922 DENND3 0.25 4.5 0.37 1.52e-5 Amyotrophic lateral sclerosis; TGCT cis rs12479064 0.604 rs11893359 chr2:99954608 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.62 -4.96 -0.41 2.29e-6 Chronic sinus infection; TGCT cis rs9894429 0.621 rs9747119 chr17:79607017 A/G cg21028142 chr17:79581711 NPLOC4 0.29 5.95 0.47 2.56e-8 Eye color traits; TGCT cis rs3087591 0.960 rs12942479 chr17:29461912 T/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.3 0.55 3.03e-11 Hip circumference; TGCT cis rs8177253 1.000 rs8177261 chr3:133480588 A/C cg20276088 chr3:133502917 NA -0.24 -5.06 -0.41 1.5e-6 Iron status biomarkers; TGCT cis rs28386778 0.863 rs3760254 chr17:61851751 T/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs6977660 0.714 rs1468287 chr7:19784210 T/A cg05791153 chr7:19748676 TWISTNB 0.84 4.86 0.4 3.49e-6 Thyroid stimulating hormone; TGCT cis rs3740393 0.562 rs11191393 chr10:104527430 C/G cg05855489 chr10:104503620 C10orf26 -0.77 -6.34 -0.49 3.94e-9 Microalbuminuria; TGCT cis rs9325144 0.534 rs1973293 chr12:38679575 C/T cg13010199 chr12:38710504 ALG10B 0.53 4.72 0.39 6.36e-6 Morning vs. evening chronotype; TGCT cis rs597539 0.731 rs664229 chr11:68624483 C/G cg04772025 chr11:68637568 NA 0.61 6.53 0.51 1.51e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9926296 0.568 rs7203907 chr16:89833774 C/G cg27121462 chr16:89883253 FANCA 0.77 8.39 0.6 8.98e-14 Vitiligo; TGCT cis rs12220238 0.818 rs16931294 chr10:75999169 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.91 0.58 1.2e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4727027 0.834 rs7811446 chr7:148773226 G/T cg23583168 chr7:148888333 NA -0.69 -8.67 -0.61 2.04e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4925325 0.876 rs6089560 chr20:60517325 T/G cg06108461 chr20:60628389 TAF4 -0.36 -4.44 -0.37 1.96e-5 Obesity-related traits; TGCT cis rs7267979 1.000 rs2257496 chr20:25279315 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10782582 0.593 rs11801414 chr1:76124517 G/A cg10523679 chr1:76189770 ACADM -0.7 -7.51 -0.56 9.94e-12 Daytime sleep phenotypes; TGCT cis rs6835098 0.961 rs2078475 chr4:174098226 A/C cg08422745 chr4:174089978 GALNT7 0.89 9.06 0.63 2.41e-15 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs60871478 0.898 rs62432225 chr7:789433 G/A cg05729249 chr7:766119 PRKAR1B;HEATR2 0.49 4.68 0.39 7.47e-6 Cerebrospinal P-tau181p levels; TGCT trans rs7618501 0.699 rs2777888 chr3:49898000 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.93 10.31 0.68 2.22e-18 Intelligence (multi-trait analysis); TGCT cis rs3820928 0.605 rs6718767 chr2:227800776 A/G cg11843606 chr2:227700838 RHBDD1 -0.51 -4.82 -0.4 4.1e-6 Pulmonary function; TGCT cis rs4788570 0.584 rs6499528 chr16:71672762 T/C cg06353428 chr16:71660113 MARVELD3 1.54 12.33 0.74 2.73e-23 Intelligence (multi-trait analysis); TGCT cis rs425277 0.606 rs12082939 chr1:2078922 C/T cg24578937 chr1:2090814 PRKCZ 0.26 6.52 0.51 1.63e-9 Height; TGCT trans rs9650657 0.513 rs4314618 chr8:10816772 A/G cg15556689 chr8:8085844 FLJ10661 -0.93 -9.85 -0.66 2.99e-17 Neuroticism; TGCT cis rs12477438 0.520 rs6741773 chr2:99738962 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.85 0.76 1.49e-24 Chronic sinus infection; TGCT cis rs2762353 0.808 rs1747522 chr6:25821807 T/A cg07061783 chr6:25882402 NA -0.42 -4.51 -0.38 1.51e-5 Blood metabolite levels; TGCT cis rs1215050 0.791 rs165244 chr4:98687889 C/T cg05340658 chr4:99064831 C4orf37 0.45 5.57 0.45 1.48e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs62244186 0.541 rs62244226 chr3:44831831 G/A cg04389838 chr3:44770851 ZNF501 -0.37 -4.77 -0.39 4.99e-6 Depressive symptoms; TGCT cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs1062177 0.756 rs2964587 chr5:151119972 C/T cg12924095 chr5:151150029 G3BP1 -0.34 -4.97 -0.41 2.17e-6 Preschool internalizing problems; TGCT cis rs9346649 0.630 rs4708641 chr6:168491416 G/A cg02770688 chr6:168491649 NA 0.34 6.05 0.48 1.6e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs66573146 0.572 rs67750430 chr4:6957266 T/G cg00086871 chr4:6988644 TBC1D14 0.88 4.62 0.38 9.39e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs6121246 0.609 rs6060627 chr20:30262159 C/T cg13852791 chr20:30311386 BCL2L1 0.8 7.55 0.56 8e-12 Mean corpuscular hemoglobin; TGCT cis rs13108904 0.517 rs13134568 chr4:1334289 G/A cg13395646 chr4:1353034 KIAA1530 -0.55 -7.57 -0.56 7.56e-12 Obesity-related traits; TGCT cis rs514406 0.505 rs440871 chr1:53173052 C/T cg01802117 chr1:53393560 SCP2 -0.38 -4.44 -0.37 1.98e-5 Monocyte count; TGCT cis rs6089584 0.888 rs6061983 chr20:60621202 T/C cg16423285 chr20:60520624 NA -0.6 -6.41 -0.5 2.76e-9 Body mass index; TGCT cis rs939658 0.626 rs11636901 chr15:79446292 T/C cg17916960 chr15:79447300 NA -0.44 -6.1 -0.48 1.28e-8 Refractive error; TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg19626725 chr5:178986131 RUFY1 0.49 6.08 0.48 1.38e-8 Lung cancer; TGCT cis rs1218582 0.774 rs4845681 chr1:154868055 G/T cg09359103 chr1:154839909 KCNN3 -0.72 -15.03 -0.8 1.01e-29 Prostate cancer; TGCT cis rs11077773 1.000 rs11077773 chr17:73060073 C/T cg27626185 chr17:73056755 KCTD2 0.64 5.57 0.45 1.47e-7 Information processing speed; TGCT cis rs3820068 0.603 rs6429769 chr1:15968610 C/G cg05660106 chr1:15850417 CASP9 0.79 7.91 0.58 1.23e-12 Systolic blood pressure; TGCT cis rs7523050 0.643 rs12736534 chr1:109399934 T/C cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs344364 0.511 rs1742469 chr16:1950244 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs651907 0.588 rs1672380 chr3:101633171 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.5 4.79 0.4 4.65e-6 Colorectal cancer; TGCT cis rs78487399 0.808 rs17030845 chr2:43687879 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.19 -0.42 8.37e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs765787 0.530 rs11636410 chr15:45535913 A/C cg24006582 chr15:45444508 DUOX1 0.25 5.53 0.44 1.8e-7 Uric acid levels; TGCT cis rs7666738 0.830 rs34135615 chr4:99001325 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9902453 0.817 rs4294865 chr17:28205736 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.12 0.48 1.15e-8 Coffee consumption (cups per day); TGCT cis rs7000551 0.646 rs2979302 chr8:22359156 G/A cg12081754 chr8:22256438 SLC39A14 0.28 4.6 0.38 1.04e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7772486 0.622 rs1292333 chr6:145982344 C/T cg13319975 chr6:146136371 FBXO30 0.52 4.8 0.4 4.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9291683 0.588 rs6857693 chr4:10018435 G/A cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Bone mineral density; TGCT cis rs2439831 0.867 rs2412778 chr15:43660982 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs12519773 0.501 rs10428523 chr5:92536365 G/A cg04854328 chr5:92914828 FLJ42709 -0.3 -4.58 -0.38 1.12e-5 Migraine; TGCT cis rs6740322 0.793 rs13414908 chr2:43546658 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -6.85 -0.52 3.13e-10 Coronary artery disease; TGCT cis rs9972944 0.756 rs6504349 chr17:63764140 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs7267979 0.868 rs6138550 chr20:25223430 C/T cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs208515 0.556 rs12206707 chr6:66697182 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.33 0.68 1.96e-18 Exhaled nitric oxide levels; TGCT cis rs4975709 0.589 rs1684967 chr5:1863055 G/C cg14773178 chr5:1868261 NA 0.3 5.12 0.42 1.12e-6 Cardiovascular disease risk factors; TGCT cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg08280861 chr8:58055591 NA 0.32 4.49 0.37 1.63e-5 Developmental language disorder (linguistic errors); TGCT cis rs6430585 0.528 rs75667274 chr2:136682486 C/T cg07169764 chr2:136633963 MCM6 1.24 12.13 0.74 8.21e-23 Corneal structure; TGCT cis rs42648 0.623 rs194505 chr7:89841307 G/A cg25739043 chr7:89950458 NA -0.53 -4.92 -0.4 2.68e-6 Homocysteine levels; TGCT cis rs1541995 1.000 rs4984609 chr15:96349079 G/A cg00882281 chr15:96346592 NA 0.29 4.8 0.4 4.46e-6 Photic sneeze reflex; TGCT cis rs992157 0.965 rs13427681 chr2:219167563 G/C cg00012203 chr2:219082015 ARPC2 0.78 8.4 0.6 8.9e-14 Colorectal cancer; TGCT cis rs11098499 0.754 rs10213267 chr4:120239074 A/G cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs3091242 0.900 rs35345536 chr1:25766488 A/G cg10117171 chr1:25599238 RHD -0.33 -5.44 -0.44 2.77e-7 Erythrocyte sedimentation rate; TGCT cis rs617219 0.671 rs13165414 chr5:78548873 C/T cg05890484 chr5:78407552 BHMT 0.34 4.63 0.38 9.24e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1784581 0.599 rs1789992 chr6:162401854 A/G cg17173639 chr6:162384350 PARK2 -0.46 -8.02 -0.58 6.6e-13 Itch intensity from mosquito bite; TGCT cis rs1975974 0.511 rs112710683 chr17:21741695 C/A cg18423549 chr17:21743878 NA -0.69 -6.64 -0.51 8.59e-10 Psoriasis; TGCT cis rs9926296 0.656 rs7191144 chr16:89823393 C/T cg27121462 chr16:89883253 FANCA 0.5 4.62 0.38 9.49e-6 Vitiligo; TGCT cis rs796364 0.760 rs56225698 chr2:200910653 A/C cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs9527 0.830 rs10883790 chr10:104640955 A/C cg15744005 chr10:104629667 AS3MT -0.51 -6.04 -0.48 1.63e-8 Arsenic metabolism; TGCT cis rs4851254 0.660 rs60697219 chr2:100699507 G/A cg22139774 chr2:100720529 AFF3 -0.43 -4.76 -0.39 5.4e-6 Intelligence (multi-trait analysis); TGCT cis rs7617773 0.823 rs9839447 chr3:48194667 T/C cg11946769 chr3:48343235 NME6 -0.61 -5.45 -0.44 2.6e-7 Coronary artery disease; TGCT cis rs9311474 0.508 rs7652191 chr3:52610415 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs877282 0.842 rs35117541 chr10:764683 C/T cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs2235642 0.859 rs9927529 chr16:1619488 C/T cg10465839 chr16:1584050 IFT140;TMEM204 -0.32 -4.92 -0.4 2.68e-6 Coronary artery disease; TGCT cis rs903263 0.965 rs10874428 chr1:84560010 G/A cg09664975 chr1:84543551 PRKACB 0.49 4.6 0.38 1.01e-5 Breast cancer (male); TGCT cis rs7412746 0.658 rs10305704 chr1:150804429 A/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.69 0.39 7.01e-6 Melanoma; TGCT cis rs1577917 0.958 rs36053156 chr6:86575509 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.42 -0.44 3.02e-7 Response to antipsychotic treatment; TGCT cis rs7584330 0.666 rs937386 chr2:238364039 C/T cg14458575 chr2:238380390 NA 0.59 8.82 0.62 8.92e-15 Prostate cancer; TGCT cis rs208520 0.874 rs208485 chr6:66925654 T/C cg07460842 chr6:66804631 NA -0.94 -9.3 -0.64 6.32e-16 Exhaled nitric oxide output; TGCT cis rs9942416 0.660 rs41534344 chr5:74997832 T/C cg02573091 chr5:74908125 NA 0.38 4.51 0.38 1.47e-5 Age-related disease endophenotypes; TGCT cis rs9818758 0.607 rs34326553 chr3:49134429 A/G cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2404602 0.684 rs1011083 chr15:77007527 C/T cg23625390 chr15:77176239 SCAPER -0.38 -4.82 -0.4 4.05e-6 Blood metabolite levels; TGCT cis rs9653442 0.564 rs11123809 chr2:100758137 C/T cg22139774 chr2:100720529 AFF3 -0.36 -5.62 -0.45 1.21e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs3097417 chr3:53088601 C/G cg27565382 chr3:53032988 SFMBT1 -0.42 -4.69 -0.39 7.17e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2204008 0.754 rs11181643 chr12:38380553 G/A cg13010199 chr12:38710504 ALG10B 0.59 4.64 0.38 8.86e-6 Bladder cancer; TGCT cis rs6669072 0.739 rs3843305 chr1:91243376 G/A cg08895590 chr1:91227319 NA -0.35 -4.65 -0.39 8.28e-6 Cognitive function; TGCT cis rs9902453 0.904 rs55633288 chr17:28368196 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs12893668 0.638 rs11851616 chr14:104065600 G/A cg26031613 chr14:104095156 KLC1 -0.55 -4.64 -0.38 8.81e-6 Reticulocyte count; TGCT cis rs28386778 0.863 rs6919 chr17:61909485 A/T cg06873352 chr17:61820015 STRADA -0.58 -6.46 -0.5 2.16e-9 Prudent dietary pattern; TGCT cis rs4819052 0.851 rs7275870 chr21:46671214 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7226408 0.857 rs1365511 chr18:34425998 G/T cg06757138 chr18:34340585 FHOD3 0.26 5.05 0.41 1.56e-6 Obesity-related traits; TGCT cis rs7178572 1.000 rs7178572 chr15:77747190 A/G cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs2180341 0.576 rs2057224 chr6:127624414 C/G cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs7072216 0.763 rs6584205 chr10:100173806 C/T cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs2948294 0.545 rs11776397 chr8:8115161 C/T cg15462221 chr8:8086144 FLJ10661 -0.6 -5.1 -0.42 1.23e-6 Red cell distribution width; TGCT cis rs3796352 1.000 rs75217232 chr3:53132373 A/C cg15956490 chr3:53032818 SFMBT1 0.54 6.37 0.5 3.42e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11190604 1.000 rs11190541 chr10:102203071 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs483180 0.512 rs597308 chr1:120214953 G/A cg19096424 chr1:120255104 PHGDH 0.56 5.26 0.43 6.1e-7 Macular telangiectasia type 2; TGCT cis rs1862618 0.853 rs43184 chr5:56141777 G/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs4819052 0.851 rs9754134 chr21:46661751 T/C cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4929949 0.688 rs10769905 chr11:8441716 C/T cg14521421 chr11:8862019 ST5 0.31 4.66 0.39 8.03e-6 Body mass index; TGCT cis rs9653442 0.527 rs12712064 chr2:100756548 C/T cg22139774 chr2:100720529 AFF3 -0.36 -5.56 -0.45 1.55e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9296092 0.517 rs9461876 chr6:33516657 C/T cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.08e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs3784262 0.528 rs4553566 chr15:58336319 T/C cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.38 -0.5 3.14e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7809950 0.723 rs62483634 chr7:106878516 G/A cg23024343 chr7:107201750 COG5 -0.44 -6.26 -0.49 5.66e-9 Coronary artery disease; TGCT cis rs1113500 0.527 rs1777482 chr1:108611374 C/G cg22161131 chr1:109420278 GPSM2 -0.51 -4.52 -0.38 1.43e-5 Growth-regulated protein alpha levels; TGCT cis rs7822232 1.000 rs7822232 chr8:145145687 A/C cg06239191 chr8:145163136 KIAA1875 -0.62 -5.71 -0.46 7.88e-8 Blood metabolite levels; TGCT cis rs1215050 0.755 rs2952911 chr4:98850666 T/C cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs908922 0.651 rs6671924 chr1:152485830 T/C cg20991723 chr1:152506922 NA 0.47 6.64 0.51 8.74e-10 Hair morphology; TGCT cis rs13191362 1.000 rs34653853 chr6:163114362 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.17 0.59 3.08e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6591182 0.504 rs7130955 chr11:65372580 C/T cg12758867 chr11:65354231 EHBP1L1 0.25 4.88 0.4 3.19e-6 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs2842992 0.915 rs1967802 chr6:160097791 G/A cg11366901 chr6:160182831 ACAT2 0.96 6.28 0.49 5.21e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg26818010 chr10:134567672 INPP5A -0.38 -5.19 -0.42 8.5e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6558530 0.932 rs7842425 chr8:1706041 G/T cg09410841 chr8:1729607 CLN8 0.85 9.29 0.64 6.66e-16 Systolic blood pressure; TGCT cis rs858239 0.537 rs2286272 chr7:23224367 T/C cg05602783 chr7:23145260 KLHL7 -0.71 -5.55 -0.45 1.68e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs769267 0.930 rs4808955 chr19:19552413 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.63 5.19 0.42 8.51e-7 Tonsillectomy; TGCT cis rs67311347 0.577 rs1880763 chr3:40283255 C/T cg13683864 chr3:40499215 RPL14 0.79 7.49 0.56 1.12e-11 Renal cell carcinoma; TGCT cis rs2730260 0.500 rs73169244 chr7:158887293 T/C cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs2299587 0.560 rs3913555 chr8:17781810 A/C cg01800426 chr8:17659068 MTUS1 -0.64 -5.52 -0.44 1.91e-7 Economic and political preferences; TGCT cis rs4478858 0.735 rs12126725 chr1:31805853 G/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs28386778 0.897 rs8069969 chr17:61822223 T/G cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs7824557 0.525 rs12682349 chr8:11245303 C/G cg21775007 chr8:11205619 TDH 0.72 7.39 0.55 1.94e-11 Retinal vascular caliber; TGCT cis rs2739330 0.796 rs5760106 chr22:24250645 A/C cg00024416 chr22:24240387 NA 0.25 4.74 0.39 5.74e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11098499 0.954 rs3890049 chr4:120326283 T/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs2354432 0.546 rs7539416 chr1:146881586 C/T cg25205988 chr1:146714368 CHD1L 1.21 7.72 0.57 3.34e-12 Mitochondrial DNA levels; TGCT cis rs301043 0.697 rs2596779 chr12:95845962 A/G cg07805603 chr12:95869602 METAP2 0.33 4.5 0.37 1.52e-5 Immature fraction of reticulocytes; TGCT cis rs3749237 1.000 rs4768 chr3:49758764 A/G cg03060546 chr3:49711283 APEH 0.74 7.6 0.56 6.37e-12 Resting heart rate; TGCT cis rs6542838 0.580 rs1607256 chr2:99543444 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.55 -5.25 -0.43 6.43e-7 Fear of minor pain; TGCT cis rs1580019 0.537 rs7804609 chr7:32558094 A/C cg07520158 chr7:32535189 LSM5;AVL9 0.56 4.86 0.4 3.42e-6 Cognitive ability; TGCT cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg03264133 chr6:25882463 NA -0.9 -8.74 -0.62 1.39e-14 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs28485415 chr4:99060340 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg18230493 chr5:56204884 C5orf35 0.86 6.85 0.52 3.07e-10 Initial pursuit acceleration; TGCT cis rs1799949 1.000 rs11655505 chr17:41278377 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs2469997 0.748 rs2470019 chr8:120362558 T/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs10032931 0.962 rs1385671 chr4:96455967 C/T cg03008707 chr4:96468962 UNC5C -0.34 -4.78 -0.39 4.79e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs611744 0.839 rs638238 chr8:109169152 A/G cg21045802 chr8:109455806 TTC35 0.69 6.06 0.48 1.51e-8 Dupuytren's disease; TGCT cis rs2549003 1.000 rs2070723 chr5:131823187 A/G cg21138405 chr5:131827807 IRF1 0.18 4.58 0.38 1.11e-5 Asthma (sex interaction); TGCT cis rs11107903 1.000 rs12372152 chr12:95520064 A/G cg10621809 chr12:95840313 NA 0.68 5.04 0.41 1.57e-6 Coronary artery disease; TGCT cis rs10510102 0.688 rs74570569 chr10:123704862 G/A cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs2594989 0.943 rs2454502 chr3:11499331 T/C cg00170343 chr3:11313890 ATG7 0.69 5.12 0.42 1.16e-6 Circulating chemerin levels; TGCT cis rs4888262 0.604 rs12935075 chr16:74676033 A/T cg01733217 chr16:74700730 RFWD3 0.73 7.26 0.55 3.68e-11 Testicular germ cell tumor; TGCT cis rs2243480 1.000 rs34703416 chr7:65300642 A/G cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs4699052 0.826 rs17033498 chr4:104179961 C/G cg16532752 chr4:104119610 CENPE -0.56 -5.09 -0.42 1.28e-6 Testicular germ cell tumor; TGCT cis rs950169 0.922 rs11635505 chr15:85097034 A/C cg11189052 chr15:85197271 WDR73 -0.77 -6.42 -0.5 2.68e-9 Schizophrenia; TGCT cis rs6840360 0.554 rs6849111 chr4:152708874 T/C cg17479576 chr4:152424074 FAM160A1 -0.51 -5.22 -0.42 7.21e-7 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.933 rs2424708 chr20:25281398 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8033133 0.836 rs11634716 chr15:25306646 C/T cg14481604 chr15:25334117 SNORD116-22 0.23 4.73 0.39 5.93e-6 Blood osmolality (transformed sodium); TGCT cis rs16958440 0.609 rs75911383 chr18:44716011 C/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs9926296 0.508 rs1558184 chr16:89842374 T/G cg26513180 chr16:89883248 FANCA 1.06 14.66 0.8 7.38e-29 Vitiligo; TGCT cis rs10949834 0.504 rs12539781 chr7:73568425 C/T cg07137043 chr7:73588983 EIF4H -0.72 -5.58 -0.45 1.45e-7 Verbal memory performance (residualized delayed recall change); TGCT cis rs3806843 0.576 rs246005 chr5:140339884 A/C cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7027203 0.759 rs10761282 chr9:96586175 G/A cg13679303 chr9:96623674 NA -0.65 -10.05 -0.67 9.45e-18 DNA methylation (variation); TGCT cis rs12765878 1.000 rs61277100 chr10:105643352 A/G cg11005552 chr10:105648138 OBFC1 0.44 7.6 0.56 6.24e-12 Coronary artery disease; TGCT cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg13607699 chr17:42295918 UBTF -0.84 -7.55 -0.56 8.34e-12 Total body bone mineral density; TGCT cis rs7772486 0.594 rs6901864 chr6:146023050 C/A cg05347473 chr6:146136440 FBXO30 -0.52 -4.81 -0.4 4.26e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7226408 0.842 rs17652345 chr18:34391493 T/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs12950390 0.853 rs8071192 chr17:45856141 A/G cg03474202 chr17:45855739 NA -0.44 -4.51 -0.38 1.5e-5 IgG glycosylation; TGCT cis rs7681440 0.904 rs7680761 chr4:90763510 A/T cg26578617 chr4:90757533 SNCA -0.49 -5.1 -0.42 1.26e-6 Dementia with Lewy bodies; TGCT cis rs367943 0.966 rs348945 chr5:112822889 C/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs11112613 0.713 rs73184081 chr12:105951745 C/T cg03607813 chr12:105948248 NA 0.47 5.72 0.46 7.49e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs524023 0.874 rs519090 chr11:64456240 G/C cg19395706 chr11:64412079 NRXN2 -0.36 -4.44 -0.37 1.96e-5 Urate levels in obese individuals; TGCT cis rs72615157 0.634 rs74742883 chr7:99785765 T/G cg00814883 chr7:100076585 TSC22D4 -0.52 -5.14 -0.42 1.06e-6 Lung function (FEV1/FVC); TGCT cis rs9653442 0.675 rs12995420 chr2:100652578 T/C cg07810366 chr2:100720526 AFF3 -0.4 -6.59 -0.51 1.14e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs799165 1.000 rs799166 chr7:73051932 C/G cg14087351 chr7:73037990 MLXIPL -0.6 -4.44 -0.37 1.99e-5 Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg26531700 chr6:26746687 NA -0.53 -5.14 -0.42 1.04e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs1495867 chr8:58155500 G/T cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs7264396 0.790 rs1040695 chr20:34244829 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.68 -0.39 7.38e-6 Total cholesterol levels; TGCT cis rs34014631 0.901 rs80213387 chr10:103717673 G/A cg22630918 chr10:102748988 C10orf2 0.42 4.78 0.39 4.86e-6 Coronary artery calcification; TGCT cis rs4563143 0.514 rs73029076 chr19:29292032 G/T cg12756686 chr19:29218302 NA 0.67 5.16 0.42 9.34e-7 Methadone dose in opioid dependence; TGCT cis rs2486288 0.656 rs11854365 chr15:45558083 G/A cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.34 -0.43 4.26e-7 Glomerular filtration rate; TGCT cis rs2153535 0.580 rs2183112 chr6:8528212 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs36051895 0.695 rs10974922 chr9:5028813 C/T cg02405213 chr9:5042618 JAK2 -0.83 -12.17 -0.74 6.58e-23 Pediatric autoimmune diseases; TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg04389838 chr3:44770851 ZNF501 0.42 5.7 0.46 8.29e-8 Depressive symptoms; TGCT cis rs589448 0.900 rs588493 chr12:69751986 G/A cg20891283 chr12:69753455 YEATS4 0.9 10.24 0.68 3.28e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs2485376 0.842 rs7077329 chr10:104161967 T/C cg26089160 chr10:104170217 PSD -0.52 -5.13 -0.42 1.09e-6 QT interval; TGCT trans rs17685 0.753 rs1639617 chr7:75701728 A/G cg19862616 chr7:65841803 NCRNA00174 0.51 8.59 0.61 3.07e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs3820928 0.874 rs10189579 chr2:227864876 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs6582630 0.502 rs7311700 chr12:38463232 T/A cg26384229 chr12:38710491 ALG10B 0.88 8.04 0.59 5.98e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs1862618 0.853 rs252916 chr5:56121788 G/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs933688 1.000 rs332531 chr5:90790451 G/C cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.94 8.24 0.59 2.07e-13 Smoking behavior; TGCT cis rs9733 0.596 rs6669369 chr1:150695892 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs854765 0.583 rs4925123 chr17:17784374 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.86 -0.58 1.61e-12 Total body bone mineral density; TGCT trans rs11722228 0.508 rs3796825 chr4:10092879 T/A cg26043149 chr18:55253948 FECH 1.16 11.23 0.71 1.26e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg25703541 chr22:24373054 LOC391322 0.84 7.14 0.54 6.85e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7953249 0.807 rs2393775 chr12:121424574 G/A cg02403541 chr12:121454288 C12orf43 -0.53 -4.56 -0.38 1.23e-5 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT trans rs10203711 0.933 rs4994754 chr2:239567218 A/G cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10465746 0.967 rs11163868 chr1:84397013 T/G cg10977910 chr1:84465055 TTLL7 0.63 6.25 0.49 5.95e-9 Obesity-related traits; TGCT cis rs7246657 0.943 rs7252099 chr19:37933780 G/A cg18154014 chr19:37997991 ZNF793 0.95 6.52 0.51 1.58e-9 Coronary artery calcification; TGCT cis rs912057 0.526 rs737449 chr6:6733729 A/G cg06612196 chr6:6737390 NA -0.47 -6.82 -0.52 3.61e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs9486719 1.000 rs12208884 chr6:96885572 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs7216064 1.000 rs62084213 chr17:65842016 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs10256972 0.721 rs10435145 chr7:1065988 C/T cg16145915 chr7:1198662 ZFAND2A -0.46 -5.46 -0.44 2.52e-7 Longevity;Endometriosis; TGCT cis rs9467773 1.000 rs6456734 chr6:26566965 G/T cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.585 rs7969814 chr12:42669657 C/G cg19980929 chr12:42632907 YAF2 0.41 5.81 0.46 4.91e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs858239 0.600 rs6461690 chr7:23135534 A/G cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 2.02e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs7586879 1.000 rs11683212 chr2:25120196 T/C cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs7772486 0.790 rs9497424 chr6:146225271 C/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.87 -0.4 3.29e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 0.965 rs9646413 chr17:41426157 A/G cg23758822 chr17:41437982 NA 0.62 6.36 0.5 3.6e-9 Menopause (age at onset); TGCT cis rs7731657 0.537 rs10478953 chr5:130185380 A/C cg08523029 chr5:130500466 HINT1 0.55 4.54 0.38 1.32e-5 Fasting plasma glucose; TGCT cis rs4886920 0.666 rs4595767 chr15:78083715 A/G cg25212270 chr15:78015279 NA -0.23 -4.86 -0.4 3.45e-6 Neuroticism; TGCT trans rs10506458 0.915 rs12423078 chr12:63397529 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs2014572 0.967 rs10411941 chr19:57762886 C/T cg24459738 chr19:57751996 ZNF805 -0.58 -5.7 -0.46 8.38e-8 Hyperactive-impulsive symptoms; TGCT trans rs561341 0.609 rs4795659 chr17:30187139 C/G cg20587970 chr11:113659929 NA 0.66 8.12 0.59 3.98e-13 Hip circumference adjusted for BMI; TGCT cis rs4927850 1.000 rs7625570 chr3:195747398 A/G cg02975922 chr3:195473998 MUC4 -0.24 -5.39 -0.44 3.4e-7 Pancreatic cancer; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg01577475 chr2:114033581 PAX8;LOC440839 -0.45 -4.8 -0.4 4.55e-6 Lymphocyte counts; TGCT cis rs11822910 1.000 rs11822910 chr11:57195917 G/A cg00522883 chr11:57194120 SLC43A3 0.36 4.61 0.38 9.93e-6 Platelet distribution width; TGCT cis rs6831352 0.877 rs2602890 chr4:100043179 C/T cg12011299 chr4:100065546 ADH4 0.42 4.99 0.41 2e-6 Alcohol dependence; TGCT cis rs10744422 0.925 rs2880678 chr12:123317099 C/T cg25930673 chr12:123319894 HIP1R -0.85 -5.01 -0.41 1.86e-6 Schizophrenia; TGCT cis rs804280 0.504 rs2645457 chr8:11614112 T/G cg26752888 chr8:11627280 NEIL2 0.72 6.13 0.48 1.06e-8 Myopia (pathological); TGCT cis rs11190604 0.767 rs10786590 chr10:102164604 T/C cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9368481 0.761 rs9379952 chr6:26987900 A/T cg26531700 chr6:26746687 NA -0.54 -4.87 -0.4 3.36e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6570726 0.935 rs387965 chr6:145869366 A/G cg23711669 chr6:146136114 FBXO30 0.72 6.97 0.53 1.68e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs11096990 0.656 rs2123027 chr4:39291113 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.51 -0.38 1.48e-5 Cognitive function; TGCT cis rs709400 0.628 rs10150072 chr14:103977605 C/T cg26031613 chr14:104095156 KLC1 0.86 9.54 0.65 1.61e-16 Body mass index; TGCT cis rs2228479 0.681 rs4287569 chr16:89957815 A/G cg06558623 chr16:89946397 TCF25 0.39 4.85 0.4 3.56e-6 Skin colour saturation; TGCT cis rs6738485 0.507 rs66569888 chr2:106886967 G/A cg16099169 chr2:106886729 NA -0.42 -4.7 -0.39 6.89e-6 Pursuit maintenance gain;Pursuit maintenance gain in psychotic disorders; TGCT cis rs12477438 0.798 rs10198293 chr2:99602929 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs2439831 1.000 rs2439831 chr15:43784475 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.99 8.01 0.58 7.16e-13 Lung cancer in ever smokers; TGCT cis rs28595532 0.920 rs114037572 chr4:119735609 T/G cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs7940866 0.801 rs2113928 chr11:130835975 A/G cg05962950 chr11:130786565 SNX19 0.76 7.3 0.55 2.95e-11 Schizophrenia; TGCT cis rs6988636 1.000 rs58741168 chr8:124191852 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs6964587 0.626 rs404 chr7:91544316 G/T cg17063962 chr7:91808500 NA -0.77 -7.32 -0.55 2.77e-11 Breast cancer; TGCT cis rs9388451 0.874 rs7739566 chr6:126094757 A/T cg05901451 chr6:126070800 HEY2 -1.02 -15.06 -0.8 8.78e-30 Brugada syndrome; TGCT cis rs28595532 0.925 rs116785973 chr4:119611350 G/A cg11846333 chr4:119757529 SEC24D 0.92 5.01 0.41 1.85e-6 Cannabis dependence symptom count; TGCT cis rs36051895 0.623 rs1120679 chr9:5248073 C/G cg02405213 chr9:5042618 JAK2 -0.72 -9.57 -0.65 1.37e-16 Pediatric autoimmune diseases; TGCT cis rs2544523 0.511 rs2544536 chr2:15906854 T/C cg26669897 chr2:15909070 NA 0.38 4.97 0.41 2.2e-6 Asthma or chronic obstructive pulmonary disease; TGCT cis rs7267979 1.000 rs6050598 chr20:25397257 C/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9583531 0.509 rs12184676 chr13:111396484 A/G cg24331049 chr13:111365604 ING1 -0.83 -5.63 -0.45 1.14e-7 Coronary artery disease; TGCT cis rs7267979 0.966 rs2261698 chr20:25259910 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7474896 0.583 rs7071147 chr10:38003376 T/C cg13720705 chr10:37990370 NA 0.34 4.9 0.4 2.9e-6 Obesity (extreme); TGCT cis rs7940866 0.801 rs10894296 chr11:130840433 T/G cg05962950 chr11:130786565 SNX19 0.73 7.14 0.54 6.88e-11 Schizophrenia; TGCT cis rs7666738 0.830 rs17027225 chr4:99028564 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs8180040 0.627 rs58956475 chr3:47224615 G/C cg27129171 chr3:47204927 SETD2 -0.7 -8.33 -0.6 1.26e-13 Colorectal cancer; TGCT cis rs2576037 0.583 rs2187091 chr18:44520048 T/C cg23302884 chr18:44338147 ST8SIA5 -0.41 -4.68 -0.39 7.26e-6 Personality dimensions; TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg07092213 chr7:1199455 ZFAND2A -0.48 -5.53 -0.44 1.83e-7 Longevity;Endometriosis; TGCT cis rs1552244 1.000 rs7622966 chr3:10139833 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs2637266 0.703 rs1660907 chr10:78494859 A/C cg18941641 chr10:78392320 NA 0.42 4.99 0.41 2.01e-6 Pulmonary function; TGCT cis rs7923609 0.811 rs7899657 chr10:65323265 G/A cg08743896 chr10:65200160 JMJD1C 0.32 4.46 0.37 1.82e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs7681440 0.874 rs1372525 chr4:90776165 G/A cg26578617 chr4:90757533 SNCA -0.44 -4.54 -0.38 1.31e-5 Dementia with Lewy bodies; TGCT cis rs698813 0.674 rs6544752 chr2:44499049 G/A cg00619915 chr2:44497795 NA -0.23 -5.32 -0.43 4.74e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs6089829 0.925 rs6062396 chr20:61667949 T/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2153535 0.580 rs962590 chr6:8450899 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg05552183 chr6:42928497 GNMT 0.52 4.57 0.38 1.16e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6912958 0.781 rs2325064 chr6:88224467 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs6095298 0.595 rs752421 chr20:47435039 G/A cg12307787 chr20:48099359 KCNB1 0.43 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs35064900 chr21:40555492 A/G cg11644478 chr21:40555479 PSMG1 1.02 10.59 0.69 4.75e-19 Cognitive function; TGCT cis rs7824557 0.564 rs1435275 chr8:11235735 T/C cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.95e-9 Retinal vascular caliber; TGCT cis rs2153535 0.580 rs7763190 chr6:8484197 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1018836 0.923 rs2187982 chr8:91556317 G/T cg16814680 chr8:91681699 NA -0.87 -9.88 -0.66 2.41e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg13395646 chr4:1353034 KIAA1530 -0.39 -4.98 -0.41 2.13e-6 Obesity-related traits; TGCT cis rs67478160 0.625 rs7141473 chr14:104316055 A/C cg26031613 chr14:104095156 KLC1 0.67 6.91 0.53 2.23e-10 Schizophrenia; TGCT cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg02891314 chr5:179741120 GFPT2 -0.39 -6.43 -0.5 2.46e-9 Height; TGCT cis rs981844 0.921 rs2606336 chr4:154656792 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs60154123 0.505 rs77990373 chr1:210041111 T/C cg04352962 chr1:209979756 IRF6 0.69 4.73 0.39 6.04e-6 Coronary artery disease; TGCT cis rs6938 0.597 rs11856413 chr15:75199892 A/G cg10253484 chr15:75165896 SCAMP2 -0.6 -5.54 -0.45 1.74e-7 Breast cancer; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg10150615 chr22:24372951 LOC391322 -0.81 -8.99 -0.63 3.41e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11031096 0.769 rs12803541 chr11:4208906 G/A cg08557956 chr11:4115526 RRM1 0.49 4.65 0.39 8.43e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9611565 0.614 rs4822053 chr22:42212936 C/A cg13695892 chr22:41940480 POLR3H -0.77 -7.18 -0.54 5.51e-11 Vitiligo; TGCT cis rs3847687 1.000 rs11061290 chr12:131518747 C/T cg13586425 chr12:131519906 GPR133 -0.33 -4.96 -0.41 2.29e-6 Longevity; TGCT cis rs7914558 0.966 rs10786745 chr10:104956827 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.85 -0.4 3.57e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6901004 0.803 rs1040903 chr6:111470153 A/C cg15721981 chr6:111408429 SLC16A10 -0.54 -4.7 -0.39 6.77e-6 Blood metabolite levels; TGCT cis rs561341 0.739 rs8070554 chr17:30216868 A/T cg13647721 chr17:30228624 UTP6 -0.61 -4.8 -0.4 4.39e-6 Hip circumference adjusted for BMI; TGCT cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg04944784 chr2:26401820 FAM59B 0.72 5.92 0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs2594989 1.000 rs2594993 chr3:11360744 C/T cg00170343 chr3:11313890 ATG7 0.66 4.87 0.4 3.39e-6 Circulating chemerin levels; TGCT cis rs6674176 0.660 rs12726706 chr1:44399942 G/A cg13606994 chr1:44402422 ARTN -0.49 -5.39 -0.44 3.36e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs929354 0.742 rs886677 chr7:157003782 T/A cg05182265 chr7:156933206 UBE3C -0.39 -8.77 -0.62 1.19e-14 Body mass index; TGCT cis rs77861329 1.000 rs352150 chr3:52209995 A/G cg08692210 chr3:52188851 WDR51A 0.94 4.83 0.4 3.91e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs704 0.523 rs11080054 chr17:26645991 G/A cg10342447 chr17:26645325 TMEM97 -0.62 -6.26 -0.49 5.78e-9 Osteoprotegerin levels; TGCT trans rs561341 0.830 rs7218801 chr17:30217778 A/G cg20587970 chr11:113659929 NA 0.8 9.45 0.65 2.65e-16 Hip circumference adjusted for BMI; TGCT cis rs916888 0.738 rs199515 chr17:44856641 C/G cg01570182 chr17:44337453 NA -0.97 -8.53 -0.61 4.19e-14 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs35306767 0.953 rs12762973 chr10:960761 C/G cg26597838 chr10:835615 NA 0.67 9.17 0.64 1.29e-15 Eosinophil percentage of granulocytes; TGCT cis rs6558174 0.965 rs2009212 chr8:22491496 G/A cg03733263 chr8:22462867 KIAA1967 0.67 5.35 0.43 4.11e-7 Breast cancer; TGCT cis rs4803468 1.000 rs284655 chr19:41928765 C/T cg09537434 chr19:41945824 ATP5SL -0.92 -10.57 -0.69 5.19e-19 Height; TGCT cis rs58904263 1 rs58904263 chr20:30401406 A/AG cg18721089 chr20:30220636 NA -0.42 -4.64 -0.38 8.8e-6 Monocyte count; TGCT cis rs9467773 0.620 rs2101582 chr6:26622734 C/T cg09904177 chr6:26538194 HMGN4 0.65 6.35 0.5 3.74e-9 Intelligence (multi-trait analysis); TGCT cis rs5769707 0.967 rs5769698 chr22:49997706 A/G cg10356904 chr22:49881777 NA -0.25 -5.05 -0.41 1.54e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs7663924 chr4:99037679 A/G cg05340658 chr4:99064831 C4orf37 -0.48 -5.45 -0.44 2.66e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3008870 0.651 rs2815376 chr1:67508531 G/A cg02640540 chr1:67518911 SLC35D1 0.59 5.58 0.45 1.41e-7 Lymphocyte percentage of white cells; TGCT trans rs3780486 0.846 rs10813954 chr9:33137596 A/C cg04842962 chr6:43655489 MRPS18A 1.24 15.76 0.82 2.18e-31 IgG glycosylation; TGCT cis rs4727027 0.901 rs11760293 chr7:148811725 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.6 0.38 1.04e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 0.41 4.58 0.38 1.14e-5 Schizophrenia; TGCT cis rs8177253 0.509 rs6762415 chr3:133478557 T/G cg08439880 chr3:133502540 NA -0.31 -5.03 -0.41 1.68e-6 Iron status biomarkers; TGCT cis rs6882076 0.884 rs7717984 chr5:156369171 A/G cg12943317 chr5:156479607 HAVCR1 0.3 5.54 0.45 1.74e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs28386778 0.734 rs12946669 chr17:62006007 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.49 4.64 0.38 8.69e-6 Prudent dietary pattern; TGCT cis rs13108904 0.604 rs13103860 chr4:1320120 G/A cg00684032 chr4:1343700 KIAA1530 0.26 5.71 0.46 7.76e-8 Obesity-related traits; TGCT cis rs4595586 0.545 rs61939643 chr12:39378460 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2562456 0.833 rs8106025 chr19:21634724 A/C cg01304269 chr19:21688519 ZNF429 -0.6 -4.89 -0.4 3.07e-6 Pain; TGCT cis rs12580194 0.593 rs73118998 chr12:55736659 T/C cg10672482 chr12:55725839 OR6C3 -0.51 -4.51 -0.38 1.46e-5 Cancer; TGCT cis rs636291 0.517 rs672606 chr1:10526144 G/A cg17425144 chr1:10567563 PEX14 0.53 7.35 0.55 2.37e-11 Prostate cancer; TGCT cis rs4911259 0.552 rs2014837 chr20:31461082 C/T cg13636640 chr20:31349939 DNMT3B 0.88 9.38 0.64 4.01e-16 Inflammatory bowel disease; TGCT cis rs2692947 0.727 rs1657502 chr2:96795608 A/C cg05933789 chr2:97190408 NA 0.15 4.45 0.37 1.91e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs864745 0.967 rs1513272 chr7:28200097 C/T cg23620719 chr7:28220237 JAZF1 -0.48 -4.45 -0.37 1.92e-5 Crohn's disease;Type 2 diabetes; TGCT cis rs7611238 0.560 rs6801007 chr3:195102447 A/T cg27323046 chr3:195102265 ACAP2 -0.36 -4.91 -0.4 2.78e-6 Body mass index; TGCT cis rs1008375 1.000 rs7661631 chr4:17679751 T/C cg16339924 chr4:17578868 LAP3 -0.59 -4.97 -0.41 2.13e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg25703541 chr22:24373054 LOC391322 0.82 6.94 0.53 1.89e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7635838 0.654 rs164101 chr3:11281082 G/A cg00170343 chr3:11313890 ATG7 0.68 6.46 0.5 2.19e-9 HDL cholesterol; TGCT cis rs57221529 0.766 rs72703026 chr5:572383 G/A cg20362242 chr5:692897 TPPP 0.51 4.56 0.38 1.21e-5 Lung disease severity in cystic fibrosis; TGCT cis rs7809950 0.678 rs17154040 chr7:107005246 C/T cg23024343 chr7:107201750 COG5 0.43 5.85 0.47 4.12e-8 Coronary artery disease; TGCT cis rs1552244 0.572 rs57268864 chr3:10164233 C/A cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs5758659 0.714 rs6002626 chr22:42517989 C/G cg15557168 chr22:42548783 NA 0.17 4.48 0.37 1.66e-5 Cognitive function; TGCT cis rs6500602 0.702 rs6500606 chr16:4502514 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.28 -5.16 -0.42 9.51e-7 Schizophrenia; TGCT cis rs713587 0.713 rs11125884 chr2:25239264 C/T cg01884057 chr2:25150051 NA 0.38 7.82 0.57 1.95e-12 Body mass index in non-asthmatics; TGCT cis rs597539 0.689 rs596874 chr11:68630874 C/T cg06112835 chr11:68658793 MRPL21 -0.45 -7.62 -0.56 5.68e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs561341 0.739 rs7213369 chr17:30211878 G/A cg20587970 chr11:113659929 NA 0.65 8.95 0.63 4.33e-15 Hip circumference adjusted for BMI; TGCT cis rs2841233 0.692 rs2028416 chr14:105348552 C/T cg03469805 chr14:105330648 KIAA0284 -0.45 -5.05 -0.41 1.55e-6 IgG glycosylation; TGCT cis rs2839186 0.933 rs4818832 chr21:47708634 C/T cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs2806561 0.704 rs2868573 chr1:23508253 C/G cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs13191362 1.000 rs4260737 chr6:163137746 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.35 0.64 4.74e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1023500 0.505 rs134874 chr22:42661144 A/G cg15557168 chr22:42548783 NA -0.22 -5.17 -0.42 9.3e-7 Schizophrenia; TGCT cis rs78487399 0.808 rs78886764 chr2:43653499 C/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.46 0.37 1.79e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg10047753 chr17:41438598 NA 0.95 9.54 0.65 1.61e-16 Menopause (age at onset); TGCT cis rs3806843 0.576 rs246064 chr5:140324309 C/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs10193935 0.901 rs12622153 chr2:42598386 C/A cg27598129 chr2:42591480 NA -0.4 -5.44 -0.44 2.71e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4074961 0.604 rs4411102 chr1:38063424 C/G cg17933807 chr1:38061675 GNL2 0.96 11.14 0.71 2.11e-20 Axial length; TGCT cis rs6896969 0.504 rs10472332 chr5:40368373 T/G cg01087697 chr5:40835557 RPL37 0.53 4.83 0.4 3.95e-6 Multiple sclerosis; TGCT cis rs7246657 0.722 rs2927747 chr19:38159530 C/T cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT cis rs539096 0.723 rs530373 chr1:44070032 C/T cg12908607 chr1:44402522 ARTN 0.45 4.66 0.39 8.02e-6 Intelligence (multi-trait analysis); TGCT cis rs2216164 1.000 rs7968411 chr12:68561575 G/A cg17065850 chr12:67807625 NA 0.24 4.47 0.37 1.73e-5 Alopecia areata; TGCT cis rs10782582 0.609 rs5745553 chr1:76379135 A/T cg10523679 chr1:76189770 ACADM -0.57 -5.22 -0.42 7.19e-7 Daytime sleep phenotypes; TGCT cis rs1372520 0.577 rs2737021 chr4:90739992 T/A cg15133208 chr4:90757351 SNCA -0.52 -5.96 -0.47 2.45e-8 Neuroticism; TGCT cis rs2243480 1.000 rs1701758 chr7:65470201 T/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs17401966 0.838 rs11579365 chr1:10470846 G/T cg19773385 chr1:10388646 KIF1B -0.22 -5.17 -0.42 9.17e-7 Hepatocellular carcinoma; TGCT cis rs2847281 0.764 rs2847277 chr18:12778032 G/T cg23598886 chr18:12777645 NA 0.36 4.54 0.38 1.3e-5 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs10131894 0.575 rs8006147 chr14:75430033 G/A cg06637938 chr14:75390232 RPS6KL1 0.55 4.83 0.4 3.97e-6 Coronary artery disease; TGCT cis rs2242116 0.932 rs1531137 chr3:46943028 T/C cg23352942 chr3:46931381 PTH1R -0.37 -5.81 -0.46 5.02e-8 Birth weight; TGCT cis rs9322193 0.923 rs9322200 chr6:149951214 G/A cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs4499344 0.730 rs614370 chr19:33106390 T/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.74 0.62 1.36e-14 Mean platelet volume; TGCT cis rs6088580 0.624 rs6120645 chr20:33025171 C/T cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs116095464 0.558 rs10043002 chr5:226753 G/A cg22857025 chr5:266934 NA -0.32 -6.53 -0.51 1.5e-9 Breast cancer; TGCT cis rs4689388 0.926 rs9998835 chr4:6293237 C/G cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2637266 0.875 rs2395409 chr10:78381004 A/G cg18941641 chr10:78392320 NA 0.43 5.57 0.45 1.49e-7 Pulmonary function; TGCT cis rs2762353 0.718 rs1165207 chr6:25865266 A/G cg03264133 chr6:25882463 NA -0.64 -7.2 -0.54 4.97e-11 Blood metabolite levels; TGCT cis rs7666738 0.830 rs28769113 chr4:98950371 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg03806693 chr22:41940476 POLR3H -1.14 -13.38 -0.77 8.05e-26 Vitiligo; TGCT cis rs10504229 0.683 rs2318148 chr8:58114955 G/A cg02725872 chr8:58115012 NA -0.37 -4.99 -0.41 1.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs9503598 0.714 rs7758776 chr6:3452245 C/T cg00476032 chr6:3446245 SLC22A23 0.2 5.95 0.47 2.5e-8 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs71301814 chr3:53117663 G/A cg07884673 chr3:53033167 SFMBT1 0.57 5.86 0.47 3.94e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs5750830 0.649 rs5750814 chr22:39797987 T/C cg24399712 chr22:39784796 NA -1.07 -13.49 -0.77 4.49e-26 Intelligence (multi-trait analysis); TGCT cis rs2777491 0.574 rs11858812 chr15:41731550 G/A cg18705301 chr15:41695430 NDUFAF1 -0.94 -17.34 -0.84 6.15e-35 Ulcerative colitis; TGCT cis rs13418410 0.539 rs11677468 chr2:33839053 T/C cg04131969 chr2:33951647 MYADML -0.78 -7.46 -0.56 1.31e-11 Non-response to antidepressants and depression; TGCT cis rs7312933 0.558 rs1796394 chr12:42826359 G/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.69 -0.46 8.61e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs6540559 0.546 rs59435160 chr1:210030730 C/A cg23283495 chr1:209979779 IRF6 0.73 5.64 0.45 1.07e-7 Cleft lip with or without cleft palate; TGCT cis rs13188771 0.633 rs350506 chr5:100874283 C/T cg18665594 chr5:101119420 NA 0.44 4.46 0.37 1.83e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs9303401 0.580 rs12946396 chr17:57164195 T/A cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs7666738 0.830 rs17550735 chr4:99014076 T/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs644799 0.710 rs10765771 chr11:95521044 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.28 0.6 1.63e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7714584 1.000 rs73284126 chr5:150261307 G/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.9 0.4 2.98e-6 Lymphocyte counts; TGCT cis rs6952808 0.609 rs11772205 chr7:1951236 C/T cg22963979 chr7:1858916 MAD1L1 -0.37 -5.58 -0.45 1.42e-7 Bipolar disorder and schizophrenia; TGCT cis rs10504229 0.683 rs7827881 chr8:58132137 C/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs56389935 chr4:119683571 G/A cg14228332 chr4:119757509 SEC24D 1.05 5.39 0.44 3.45e-7 Cannabis dependence symptom count; TGCT cis rs6542838 0.702 rs6739176 chr2:99536846 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.57 -5.44 -0.44 2.74e-7 Fear of minor pain; TGCT cis rs4665809 0.590 rs62128457 chr2:26467347 C/A cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs9303401 0.573 rs34717648 chr17:56886624 T/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs7666738 0.830 rs28618180 chr4:98912184 A/C cg05340658 chr4:99064831 C4orf37 0.54 6.51 0.5 1.7e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs12142240 0.659 rs72677602 chr1:46837487 G/A cg14993813 chr1:46806288 NSUN4 -0.57 -4.72 -0.39 6.32e-6 Menopause (age at onset); TGCT cis rs854765 0.693 rs4924823 chr17:17764502 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.65 -0.57 4.87e-12 Total body bone mineral density; TGCT cis rs6121246 0.528 rs6060252 chr20:30191084 A/G cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs2839186 0.967 rs17176131 chr21:47705237 T/C cg13732083 chr21:47605072 C21orf56 0.34 4.52 0.38 1.44e-5 Testicular germ cell tumor; TGCT cis rs7772486 0.754 rs702324 chr6:146008793 A/G cg13319975 chr6:146136371 FBXO30 0.54 4.81 0.4 4.29e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1691799 0.899 rs1168307 chr12:66739539 A/G cg16791601 chr12:66731901 HELB -0.28 -6.17 -0.48 8.87e-9 White blood cell count (basophil); TGCT cis rs600550 0.926 rs675655 chr11:60020874 G/C cg18570331 chr11:60101691 MS4A6E 0.52 4.48 0.37 1.67e-5 Lipoprotein-associated phospholipase A2 activity and mass; TGCT cis rs9549367 0.826 rs1885688 chr13:113894236 G/T cg18105134 chr13:113819100 PROZ -0.35 -5.89 -0.47 3.46e-8 Platelet distribution width; TGCT cis rs7216064 0.532 rs3890640 chr17:66053028 C/T cg12091567 chr17:66097778 LOC651250 1.17 9.62 0.65 1.04e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9787249 0.915 rs58589165 chr1:40213670 A/T cg20968010 chr1:40505947 CAP1 -0.53 -5.0 -0.41 1.91e-6 Blood protein levels; TGCT cis rs4786125 0.581 rs1967404 chr16:6921483 G/A cg03623568 chr16:6915990 A2BP1 -0.45 -6.68 -0.51 7.28e-10 Heart rate variability traits (SDNN); TGCT cis rs4332037 0.539 rs11762545 chr7:2060775 C/T cg25834613 chr7:1915315 MAD1L1 -0.51 -4.99 -0.41 1.95e-6 Bipolar disorder; TGCT cis rs7812088 0.901 rs73169679 chr7:150953855 C/T cg03289901 chr7:150933506 CHPF2 0.36 4.62 0.38 9.61e-6 Bone mineral density; TGCT cis rs2688608 0.592 rs7909544 chr10:75484004 G/C cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs28595532 0.844 rs80188901 chr4:119500014 C/T cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.8e-7 Cannabis dependence symptom count; TGCT cis rs1895302 0.634 rs4867917 chr5:169538188 C/T cg23221885 chr5:170171749 NA 0.29 4.64 0.38 8.87e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (all platinum-based drugs); TGCT cis rs11696501 0.694 rs6094184 chr20:44256575 G/A cg11783356 chr20:44313418 WFDC10B -0.32 -4.63 -0.38 9.25e-6 Brain structure; TGCT trans rs1814175 0.791 rs1722023 chr11:49908136 G/C cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs72781680 0.716 rs2712061 chr2:24026411 G/A cg08917208 chr2:24149416 ATAD2B 0.79 4.94 0.41 2.51e-6 Lymphocyte counts; TGCT cis rs2742417 0.603 rs2673075 chr3:45778288 C/A cg04837898 chr3:45731254 SACM1L -0.67 -7.3 -0.55 3.06e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6121246 0.697 rs45557936 chr20:30226690 G/A cg13852791 chr20:30311386 BCL2L1 0.74 4.84 0.4 3.77e-6 Mean corpuscular hemoglobin; TGCT cis rs10197940 0.510 rs7557092 chr2:152423459 T/A cg19508488 chr2:152266495 RIF1 0.63 5.69 0.46 8.47e-8 Lung cancer; TGCT cis rs4722166 0.630 rs4722169 chr7:22785419 C/T cg26061582 chr7:22766209 IL6 0.57 7.31 0.55 2.85e-11 Lung cancer; TGCT cis rs7829975 0.742 rs12547493 chr8:8661534 C/T cg06636001 chr8:8085503 FLJ10661 -0.64 -5.75 -0.46 6.46e-8 Mood instability; TGCT cis rs2760061 0.819 rs1745416 chr1:228204497 G/A cg18477163 chr1:228402036 OBSCN 0.34 7.22 0.54 4.65e-11 Diastolic blood pressure; TGCT cis rs12142240 0.698 rs17361833 chr1:46828700 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs3770081 1.000 rs3770087 chr2:86267068 T/C cg23655155 chr2:86332777 POLR1A;PTCD3 -1.18 -4.81 -0.4 4.33e-6 Facial emotion recognition (sad faces); TGCT cis rs9486719 1.000 rs926276 chr6:96868735 C/T cg06623918 chr6:96969491 KIAA0776 0.97 9.2 0.64 1.06e-15 Migraine;Coronary artery disease; TGCT cis rs4455778 0.580 rs4437600 chr7:49090274 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs2404602 0.692 rs12911902 chr15:77053575 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs2455799 0.573 rs2455836 chr3:15754538 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.69 -0.39 7.09e-6 Mean platelet volume; TGCT cis rs17376456 0.877 rs28418572 chr5:93144161 A/C cg21475434 chr5:93447410 FAM172A 0.6 4.58 0.38 1.13e-5 Diabetic retinopathy; TGCT cis rs12042938 0.600 rs1094655 chr1:231774362 A/G cg04892437 chr1:231737901 TSNAX-DISC1 0.46 4.79 0.4 4.68e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs7666738 0.830 rs6843777 chr4:98866635 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.13 0.42 1.09e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.964 rs854813 chr17:18003845 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.65 -6.31 -0.49 4.57e-9 Total body bone mineral density; TGCT cis rs7954584 0.626 rs12809676 chr12:122442381 C/A cg21016266 chr12:122356598 WDR66 0.54 6.64 0.51 8.76e-10 Mean corpuscular volume; TGCT cis rs11148252 0.595 rs9526974 chr13:53251040 C/G cg00495681 chr13:53174319 NA 0.67 6.59 0.51 1.13e-9 Lewy body disease; TGCT cis rs7412746 0.658 rs6657388 chr1:150748786 A/G cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs1008375 1.000 rs10011865 chr4:17645710 G/A cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9303401 0.659 rs17222621 chr17:56695923 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs9902453 0.904 rs9894893 chr17:28270350 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.87 8.26 0.6 1.9e-13 Coffee consumption (cups per day); TGCT cis rs6138458 1.000 rs4273288 chr20:24900873 G/A cg26195577 chr20:24973756 C20orf3 -1.2 -12.04 -0.73 1.35e-22 Blood protein levels; TGCT cis rs4455778 0.580 rs7808387 chr7:49125122 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs8177253 0.828 rs8177259 chr3:133480388 T/C cg20276088 chr3:133502917 NA -0.24 -5.05 -0.41 1.53e-6 Iron status biomarkers; TGCT cis rs7727544 0.716 rs72793278 chr5:131561372 C/A cg24060327 chr5:131705240 SLC22A5 -0.54 -5.1 -0.42 1.22e-6 Blood metabolite levels; TGCT cis rs7178572 0.568 rs7177533 chr15:77387923 C/T cg22256960 chr15:77711686 NA -0.84 -8.34 -0.6 1.23e-13 Type 2 diabetes; TGCT cis rs1799949 0.931 rs9891977 chr17:41437398 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.46 4.9 0.4 2.91e-6 Menopause (age at onset); TGCT cis rs1801251 1.000 rs283476 chr2:233650168 A/G cg08000102 chr2:233561755 GIGYF2 0.65 6.45 0.5 2.28e-9 Coronary artery disease; TGCT cis rs1757171 0.534 rs2797793 chr6:37477262 C/T cg25019722 chr6:37503610 NA 0.42 6.02 0.48 1.87e-8 Cognitive performance; TGCT cis rs12887734 0.524 rs4906363 chr14:104210239 G/A cg26031613 chr14:104095156 KLC1 -0.71 -6.14 -0.48 1.04e-8 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs75686122 0.892 rs17806929 chr8:104571608 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9914988 0.887 rs4795456 chr17:27072463 G/A cg20469991 chr17:27169893 C17orf63 -0.73 -5.11 -0.42 1.17e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7086627 0.515 rs11202963 chr10:82210392 A/G cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs56104184 0.615 rs73061693 chr19:49399941 C/A cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7914558 1.000 rs1890184 chr10:104748459 A/C cg04362960 chr10:104952993 NT5C2 0.62 5.51 0.44 2.03e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs8103278 1.000 rs725660 chr19:46262286 C/A cg14061069 chr19:46274453 DMPK -0.44 -6.34 -0.49 3.86e-9 Coronary artery disease; TGCT cis rs7943203 0.525 rs920679 chr11:108038477 C/T cg04873221 chr11:107992290 ACAT1 0.64 4.72 0.39 6.23e-6 Red blood cell count;Mean corpuscular volume; TGCT cis rs3924048 0.574 rs11121928 chr1:12615888 C/G cg00291366 chr1:12616550 NA 0.32 5.05 0.41 1.54e-6 Optic cup area; TGCT cis rs2243480 1.000 rs160637 chr7:65584318 C/T cg18252515 chr7:66147081 NA -1.24 -8.1 -0.59 4.35e-13 Diabetic kidney disease; TGCT cis rs12477438 0.798 rs6736064 chr2:99658201 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs2594989 0.943 rs6784861 chr3:11465568 T/C cg00170343 chr3:11313890 ATG7 0.72 5.37 0.43 3.8e-7 Circulating chemerin levels; TGCT cis rs17270561 1.000 rs17270561 chr6:25820439 A/C cg17042849 chr6:26104293 HIST1H4C 0.82 5.59 0.45 1.39e-7 Iron status biomarkers; TGCT cis rs4246215 1 rs4246215 chr11:61564299 G/T cg19610905 chr11:61596333 FADS2 -1.07 -11.4 -0.72 5.06e-21 Plasma omega-3 polyunsaturated fatty acid levels (alphalinolenic acid);Platelet count;Inflammatory bowel disease;Trans fatty acid levels;Crohn's disease;Plasma omega-3 polyunsaturated fatty acid level (eicosapentaenoic acid);Red blood cell fatty acid levels;Plasma omega-3 polyunsaturated fatty acid levels (docosapentaenoic acid); TGCT cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg06238570 chr21:40685208 BRWD1 -0.8 -9.12 -0.63 1.7e-15 Cognitive function; TGCT trans rs1005277 0.579 rs2474568 chr10:38383147 A/T cg27523141 chr10:43048294 ZNF37B 0.73 8.42 0.6 7.92e-14 Extrinsic epigenetic age acceleration; TGCT cis rs1799949 0.931 rs34410138 chr17:41279770 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.15 0.42 1e-6 Menopause (age at onset); TGCT cis rs7666738 0.830 rs10440379 chr4:98902822 G/T cg18180107 chr4:99064573 C4orf37 0.53 4.81 0.4 4.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs709400 0.663 rs9671911 chr14:103967343 T/C cg26031613 chr14:104095156 KLC1 0.84 9.5 0.65 2.08e-16 Body mass index; TGCT cis rs3785574 0.925 rs2727340 chr17:61970224 T/A cg11494091 chr17:61959527 GH2 0.41 6.97 0.53 1.67e-10 Height; TGCT cis rs2688608 0.901 rs2675671 chr10:75632760 C/T cg19442545 chr10:75533431 FUT11 -0.29 -4.75 -0.39 5.46e-6 Inflammatory bowel disease; TGCT cis rs10501293 0.703 rs4561205 chr11:42988504 A/T cg03447554 chr11:43094025 NA 0.44 6.45 0.5 2.25e-9 Cognitive performance; TGCT cis rs1218582 0.710 rs9793588 chr1:154878878 C/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.97 -0.53 1.64e-10 Prostate cancer; TGCT cis rs7666738 0.830 rs35939134 chr4:98980311 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.861 rs11206011 chr1:53235910 T/C cg22166914 chr1:53195759 ZYG11B -0.39 -6.57 -0.51 1.22e-9 Monocyte count; TGCT cis rs709400 0.930 rs61996717 chr14:104048571 T/C cg26031613 chr14:104095156 KLC1 1.17 16.1 0.82 3.56e-32 Body mass index; TGCT cis rs896854 0.738 rs509594 chr8:95967156 C/G cg13393036 chr8:95962371 TP53INP1 0.56 6.85 0.52 2.99e-10 Type 2 diabetes; TGCT cis rs12900413 0.603 rs2882678 chr15:90299542 A/G cg24249390 chr15:90295951 MESP1 -0.29 -5.03 -0.41 1.7e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg11965913 chr1:205819406 PM20D1 0.52 7.21 0.54 4.73e-11 Menarche (age at onset); TGCT cis rs6964587 0.872 rs57969083 chr7:91665627 A/T cg22709100 chr7:91322751 NA 0.28 4.51 0.38 1.49e-5 Breast cancer; TGCT cis rs4727027 0.870 rs11525060 chr7:148801091 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.68 0.39 7.53e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7429990 0.965 rs7651237 chr3:48105528 A/G cg11946769 chr3:48343235 NME6 -0.61 -4.7 -0.39 6.69e-6 Educational attainment (years of education); TGCT cis rs7017914 0.905 rs2732116 chr8:71929327 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs1891275 0.515 rs7093728 chr10:93443617 C/T cg07889827 chr10:93443413 NA -0.33 -6.99 -0.53 1.53e-10 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs2168111 chr3:40395325 T/G cg13683864 chr3:40499215 RPL14 -1.02 -10.8 -0.7 1.43e-19 Renal cell carcinoma; TGCT cis rs4455778 0.580 rs4273799 chr7:49079809 T/C cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs910316 0.967 rs8013444 chr14:75661981 A/G cg08847533 chr14:75593920 NEK9 -0.93 -9.92 -0.67 1.95e-17 Height; TGCT cis rs6951245 0.935 rs61910751 chr7:1097895 A/G cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3540 0.513 rs2589963 chr15:90922675 A/G cg22089800 chr15:90895588 ZNF774 0.82 9.04 0.63 2.61e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7100689 0.622 rs2994389 chr10:82062257 C/G cg01528321 chr10:82214614 TSPAN14 0.75 7.46 0.56 1.32e-11 Post bronchodilator FEV1; TGCT cis rs4780401 0.609 rs12927966 chr16:11814562 C/T cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs2147959 0.941 rs10916317 chr1:228645063 A/G cg22700015 chr1:228743131 NA -0.57 -4.5 -0.37 1.55e-5 Adult asthma; TGCT cis rs3796352 1.000 rs75217232 chr3:53132373 A/C cg27565382 chr3:53032988 SFMBT1 0.4 4.44 0.37 1.94e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs916888 0.773 rs199535 chr17:44822662 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 -0.63 -5.5 -0.44 2.06e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs57221529 0.709 rs72707024 chr5:667915 G/A cg16624210 chr5:671434 TPPP 0.42 4.71 0.39 6.61e-6 Lung disease severity in cystic fibrosis; TGCT cis rs950027 0.549 rs9920634 chr15:45596546 G/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.4 -0.55 1.76e-11 Response to fenofibrate (adiponectin levels); TGCT cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg03517284 chr6:25882590 NA 0.5 4.58 0.38 1.12e-5 Intelligence (multi-trait analysis); TGCT cis rs9921338 0.961 rs7202814 chr16:11389774 C/T cg00044050 chr16:11439710 C16orf75 -0.96 -6.92 -0.53 2.16e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs35160687 0.842 rs10200526 chr2:86527599 G/A cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.48e-7 Night sleep phenotypes; TGCT cis rs2153535 0.601 rs1737581 chr6:8539138 A/G cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2688608 0.901 rs2675671 chr10:75632760 C/T cg04320760 chr10:75533139 FUT11 -0.3 -4.7 -0.39 6.79e-6 Inflammatory bowel disease; TGCT cis rs2439831 1.000 rs690002 chr15:43729349 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs6701037 0.566 rs4344281 chr1:175135376 C/T cg00321850 chr1:175162397 KIAA0040 0.38 5.02 0.41 1.71e-6 Alcohol dependence; TGCT cis rs8077889 1.000 rs2079005 chr17:41865627 T/G cg26893861 chr17:41843967 DUSP3 1.08 13.1 0.76 3.73e-25 Triglycerides; TGCT cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg25151919 chr3:44754333 ZNF502 -0.39 -4.58 -0.38 1.12e-5 Depressive symptoms; TGCT cis rs736408 0.609 rs13095332 chr3:52787242 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -5.13 -0.42 1.09e-6 Bipolar disorder; TGCT cis rs6866344 0.697 rs11749438 chr5:178131245 C/T cg03877680 chr5:178157825 ZNF354A 0.73 5.93 0.47 2.85e-8 Neutrophil percentage of white cells; TGCT cis rs114540395 0.925 rs12244100 chr10:103379397 T/C cg18276125 chr10:102749041 C10orf2 0.39 4.68 0.39 7.31e-6 Schizophrenia; TGCT cis rs2439831 0.867 rs8039638 chr15:43634405 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg15659132 chr6:26577336 NA -0.56 -5.55 -0.45 1.62e-7 Schizophrenia; TGCT trans rs629535 0.508 rs56207225 chr8:70146628 C/A cg21567404 chr3:27674614 NA -0.52 -7.76 -0.57 2.74e-12 Dupuytren's disease; TGCT cis rs2549003 0.811 rs10035166 chr5:131823927 C/T cg21138405 chr5:131827807 IRF1 -0.19 -4.75 -0.39 5.55e-6 Asthma (sex interaction); TGCT cis rs875971 0.929 rs6970860 chr7:65976634 A/G cg18876405 chr7:65276391 NA 0.31 4.8 0.4 4.53e-6 Aortic root size; TGCT cis rs854765 0.654 rs9911281 chr17:17762457 G/C cg04398451 chr17:18023971 MYO15A 0.29 4.57 0.38 1.15e-5 Total body bone mineral density; TGCT cis rs12579753 0.789 rs35448307 chr12:82165817 A/G cg07988820 chr12:82153109 PPFIA2 -0.69 -7.77 -0.57 2.56e-12 Resting heart rate; TGCT cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT trans rs17685 0.712 rs7778735 chr7:75770237 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs28595532 0.844 rs115411027 chr4:119490685 T/C cg11846333 chr4:119757529 SEC24D 0.93 5.08 0.42 1.32e-6 Cannabis dependence symptom count; TGCT cis rs13188771 0.690 rs352055 chr5:100871666 A/T cg18665594 chr5:101119420 NA 0.45 4.5 0.37 1.56e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs10114408 0.959 rs10761304 chr9:96656982 A/G cg13679303 chr9:96623674 NA -0.36 -4.65 -0.39 8.37e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6429082 0.749 rs291362 chr1:235686690 T/A cg26050004 chr1:235667680 B3GALNT2 0.64 5.99 0.47 2.13e-8 Adiposity; TGCT trans rs561341 0.800 rs7209766 chr17:30234848 T/A cg20587970 chr11:113659929 NA -0.68 -9.45 -0.65 2.75e-16 Hip circumference adjusted for BMI; TGCT trans rs1814175 0.615 rs12417290 chr11:49876951 G/A cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs6922269 0.748 rs6902664 chr6:151252917 A/G cg21950534 chr6:152128483 ESR1 -0.52 -4.55 -0.38 1.24e-5 Coronary heart disease; TGCT cis rs7249142 0.549 rs1858846 chr19:19281187 T/G cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.55 0.45 1.66e-7 IgG glycosylation; TGCT cis rs17718580 0.826 rs72679533 chr14:50996692 G/T cg04730355 chr14:51134070 SAV1 1.0 5.61 0.45 1.24e-7 Cognitive performance; TGCT cis rs4285028 0.699 rs1574115 chr3:121469225 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.99 -7.86 -0.58 1.55e-12 Multiple sclerosis; TGCT cis rs2663905 0.611 rs2663924 chr15:81392903 T/G cg18837035 chr15:81426597 C15orf26 -0.55 -4.77 -0.39 5.15e-6 QT interval (drug interaction); TGCT cis rs5769707 1.000 rs5769707 chr22:50013402 G/T cg20744362 chr22:50050164 C22orf34 0.27 4.48 0.37 1.67e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9486719 0.948 rs2472881 chr6:96862562 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs1862618 0.671 rs252897 chr5:56223000 G/A cg18230493 chr5:56204884 C5orf35 -0.51 -4.48 -0.37 1.7e-5 Initial pursuit acceleration; TGCT cis rs9928842 0.664 rs7205074 chr16:75220009 A/C cg09066997 chr16:75300724 BCAR1 -0.23 -4.77 -0.39 5.14e-6 Alcoholic chronic pancreatitis; TGCT cis rs9611565 0.729 rs73176686 chr22:41782119 C/T cg03806693 chr22:41940476 POLR3H -1.16 -13.37 -0.77 8.59e-26 Vitiligo; TGCT cis rs2075371 0.933 rs1833474 chr7:133958240 A/G cg11752832 chr7:134001865 SLC35B4 0.68 5.89 0.47 3.32e-8 Mean platelet volume; TGCT cis rs6430585 0.528 rs660002 chr2:136723504 C/T cg07169764 chr2:136633963 MCM6 1.22 11.95 0.73 2.26e-22 Corneal structure; TGCT cis rs912057 0.526 rs201061 chr6:6730512 C/T cg06612196 chr6:6737390 NA -0.49 -7.19 -0.54 5.25e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs6840360 0.967 rs7695162 chr4:152510541 G/A cg17479576 chr4:152424074 FAM160A1 -0.43 -4.54 -0.38 1.29e-5 Intelligence (multi-trait analysis); TGCT cis rs13082711 1.000 rs73050029 chr3:27514760 C/A cg02860705 chr3:27208620 NA 0.34 4.77 0.39 5.18e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7528684 0.648 rs7546623 chr1:157761419 C/T cg17134153 chr1:157670328 FCRL3 -0.27 -4.86 -0.4 3.51e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs67311347 0.713 rs9861194 chr3:40309225 C/T cg13683864 chr3:40499215 RPL14 -0.87 -8.51 -0.61 4.77e-14 Renal cell carcinoma; TGCT cis rs7726839 0.574 rs12517345 chr5:628294 G/A cg16624210 chr5:671434 TPPP 0.42 4.68 0.39 7.38e-6 Obesity-related traits; TGCT cis rs769267 0.896 rs7253807 chr19:19631444 A/T cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs751728 0.965 rs4713681 chr6:33754817 T/C cg00334056 chr6:33755658 LEMD2 -0.26 -4.69 -0.39 7.12e-6 Crohn's disease; TGCT cis rs9790314 0.871 rs336561 chr3:161125305 C/T cg03342759 chr3:160939853 NMD3 -0.49 -5.13 -0.42 1.08e-6 Morning vs. evening chronotype; TGCT cis rs4664308 0.967 rs17831329 chr2:160915819 T/C cg03641300 chr2:160917029 PLA2R1 -0.26 -6.46 -0.5 2.13e-9 Idiopathic membranous nephropathy; TGCT cis rs13108904 0.604 rs13103860 chr4:1320120 G/A cg03303774 chr4:1407052 NA 0.37 5.98 0.47 2.26e-8 Obesity-related traits; TGCT cis rs6988636 1.000 rs60362869 chr8:124189971 A/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs1215050 0.743 rs6532692 chr4:98648005 C/A cg17366294 chr4:99064904 C4orf37 -0.52 -5.51 -0.44 1.97e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs144345632 1 rs144345632 chr6:96886894 T/TA cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs11690935 0.632 rs11690807 chr2:172628120 G/A cg13550731 chr2:172543902 DYNC1I2 0.68 6.0 0.47 2.02e-8 Schizophrenia; TGCT cis rs853679 0.550 rs1225599 chr6:28165190 C/T cg12963246 chr6:28129442 ZNF389 0.48 4.74 0.39 5.69e-6 Depression; TGCT cis rs78456975 0.550 rs111467480 chr2:1569154 A/G cg01028140 chr2:1542097 TPO -0.34 -5.22 -0.42 7.31e-7 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs62064224 0.606 rs61390192 chr17:30837447 C/T cg18200150 chr17:30822561 MYO1D 0.51 6.66 0.51 7.87e-10 Schizophrenia; TGCT cis rs2032447 0.832 rs10425 chr6:26056549 A/G cg03517284 chr6:25882590 NA -0.66 -5.82 -0.46 4.67e-8 Intelligence (multi-trait analysis); TGCT cis rs8177253 1.000 rs8177252 chr3:133480174 C/A cg08439880 chr3:133502540 NA -0.31 -5.91 -0.47 3.08e-8 Iron status biomarkers; TGCT cis rs61008539 0.893 rs7783487 chr7:860160 A/C cg00475322 chr7:917719 C7orf20 0.47 6.04 0.48 1.68e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs9640161 0.871 rs56156367 chr7:150047201 A/T cg10018233 chr7:150070692 REPIN1 0.31 4.52 0.38 1.42e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs950169 0.922 rs2033284 chr15:84946273 C/T cg12863693 chr15:85201151 NMB 0.45 4.93 0.41 2.55e-6 Schizophrenia; TGCT cis rs1005277 0.579 rs2474569 chr10:38383491 C/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.2 -0.59 2.5e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.5 5.64 0.45 1.11e-7 Lymphocyte counts; TGCT cis rs7192750 0.586 rs2018384 chr16:71940825 T/C cg06353428 chr16:71660113 MARVELD3 0.83 7.25 0.55 3.86e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2180341 0.618 rs12199451 chr6:127597780 C/G cg27446573 chr6:127587934 RNF146 0.63 5.58 0.45 1.42e-7 Breast cancer; TGCT cis rs9309473 0.660 rs17349321 chr2:73643753 C/T cg07208825 chr2:73871855 ALMS1P 0.25 4.54 0.38 1.33e-5 Metabolite levels; TGCT cis rs10782582 0.609 rs112431348 chr1:76275571 A/G cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs7666738 0.800 rs12163918 chr4:98835794 T/C cg05340658 chr4:99064831 C4orf37 0.53 6.18 0.49 8.5e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.512 rs9611667 chr22:42187015 C/T cg06634786 chr22:41940651 POLR3H -0.84 -7.83 -0.57 1.91e-12 Vitiligo; TGCT cis rs3849570 0.695 rs62265411 chr3:81573660 T/C cg07356753 chr3:81810745 GBE1 -0.61 -5.1 -0.42 1.24e-6 Waist circumference;Body mass index; TGCT cis rs7119 0.689 rs11630926 chr15:77819582 T/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.55 -0.38 1.27e-5 Type 2 diabetes; TGCT cis rs9816784 0.566 rs11720913 chr3:195832560 T/C cg14488913 chr3:195402182 SDHAP2 -0.35 -4.47 -0.37 1.71e-5 Mean corpuscular hemoglobin; TGCT cis rs4891159 0.790 rs72973773 chr18:74115176 T/C cg24786174 chr18:74118243 ZNF516 -0.62 -9.4 -0.65 3.56e-16 Longevity; TGCT cis rs10838532 0.591 rs11038743 chr11:46029826 T/A cg10516359 chr11:45827763 SLC35C1 -0.38 -4.45 -0.37 1.92e-5 Axial length; TGCT cis rs12142240 0.698 rs41294456 chr1:46809782 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs12478296 0.581 rs4973645 chr2:242993577 T/C cg06360820 chr2:242988706 NA -0.8 -5.22 -0.42 7.18e-7 Obesity-related traits; TGCT cis rs9916302 0.904 rs4795355 chr17:37427382 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs9322193 0.923 rs62441279 chr6:150042330 G/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg12386194 chr3:101231763 SENP7 0.59 5.39 0.44 3.43e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4253772 0.513 rs6008597 chr22:46703904 A/C cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg21548813 chr6:291882 DUSP22 0.67 7.24 0.55 4.14e-11 Menopause (age at onset); TGCT cis rs73110464 0.609 rs4919752 chr12:53359229 G/C cg05393297 chr12:53359155 NA -0.79 -8.5 -0.61 5.05e-14 Cancer (pleiotropy); TGCT cis rs769267 0.930 rs1047361 chr19:19606634 G/A cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs4788570 0.615 rs7206470 chr16:71668800 G/A cg06353428 chr16:71660113 MARVELD3 1.55 12.46 0.75 1.33e-23 Intelligence (multi-trait analysis); TGCT trans rs208520 0.690 rs207112 chr6:66792092 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs2456568 0.771 rs2102333 chr11:93634749 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -6.44 -0.5 2.38e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2836974 0.897 rs6517513 chr21:40526878 A/G cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs916888 0.821 rs199513 chr17:44856932 A/G cg01570182 chr17:44337453 NA -0.88 -8.06 -0.59 5.56e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7178572 0.568 rs1125617 chr15:77532711 A/G cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs9926296 0.632 rs2011925 chr16:89814064 T/G cg27121462 chr16:89883253 FANCA 0.58 5.29 0.43 5.29e-7 Vitiligo; TGCT cis rs1799949 1.000 rs16942 chr17:41244000 T/C cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 9.05e-28 Menopause (age at onset); TGCT cis rs7811142 0.779 rs111312383 chr7:99905325 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.68 0.61 1.9e-14 Platelet count; TGCT cis rs28595532 1.000 rs11938970 chr4:119660152 A/G cg21605333 chr4:119757512 SEC24D 1.35 7.72 0.57 3.38e-12 Cannabis dependence symptom count; TGCT cis rs1801251 1.000 rs283471 chr2:233656627 G/A cg25237894 chr2:233734115 C2orf82 0.27 4.68 0.39 7.35e-6 Coronary artery disease; TGCT cis rs394563 0.775 rs420430 chr6:149785539 T/G cg03678062 chr6:149772716 ZC3H12D -0.36 -4.45 -0.37 1.87e-5 Dupuytren's disease; TGCT cis rs10465746 0.933 rs2224990 chr1:84436275 C/A cg10977910 chr1:84465055 TTLL7 0.63 6.23 0.49 6.49e-9 Obesity-related traits; TGCT cis rs7818688 0.697 rs58282276 chr8:95985391 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs78461346 0.610 rs111617764 chr17:80468182 A/G cg15014069 chr17:80540666 FOXK2 0.38 4.63 0.38 9.19e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs9653442 0.628 rs12474386 chr2:100857017 G/A cg22139774 chr2:100720529 AFF3 -0.39 -6.41 -0.5 2.73e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs1008375 0.932 rs13127157 chr4:17618049 A/G cg16339924 chr4:17578868 LAP3 -0.71 -5.7 -0.46 8.27e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1865760 0.865 rs4478388 chr6:25953633 A/G cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT cis rs9549260 0.753 rs61963264 chr13:41154792 G/A cg21288729 chr13:41239152 FOXO1 0.68 4.75 0.39 5.58e-6 Red blood cell count; TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs3772130 1.000 rs34086988 chr3:121352745 G/C cg01951420 chr3:121553821 IQCB1;EAF2 0.55 4.95 0.41 2.35e-6 Cognitive performance; TGCT cis rs2836950 0.805 rs2836961 chr21:40627020 A/C cg06238570 chr21:40685208 BRWD1 -0.57 -5.68 -0.45 9.16e-8 Menarche (age at onset); TGCT cis rs9303401 0.538 rs35454383 chr17:56475599 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.62 0.45 1.18e-7 Cognitive test performance; TGCT cis rs9311474 0.508 rs6805156 chr3:52609362 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Electroencephalogram traits; TGCT cis rs6121246 0.559 rs6058468 chr20:30406448 C/A cg13852791 chr20:30311386 BCL2L1 0.79 7.34 0.55 2.42e-11 Mean corpuscular hemoglobin; TGCT cis rs6933660 0.745 rs6912830 chr6:151743629 A/C cg14416726 chr6:151773293 C6orf211;RMND1 -0.87 -9.56 -0.65 1.45e-16 Menarche (age at onset); TGCT cis rs6840360 0.571 rs4696098 chr4:152489053 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs7635838 0.617 rs2122031 chr3:11314143 G/A cg00170343 chr3:11313890 ATG7 0.61 5.98 0.47 2.16e-8 HDL cholesterol; TGCT cis rs3099143 1.000 rs7178759 chr15:77143513 A/G cg21673338 chr15:77095150 SCAPER 0.51 5.03 0.41 1.65e-6 Recalcitrant atopic dermatitis; TGCT cis rs4819052 0.851 rs13048789 chr21:46660714 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs17345786 1.000 rs3804778 chr3:101294572 C/T cg12386194 chr3:101231763 SENP7 0.59 5.39 0.44 3.43e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9926296 0.533 rs7190823 chr16:89866043 A/G cg03388025 chr16:89894329 SPIRE2 0.48 8.34 0.6 1.21e-13 Vitiligo; TGCT cis rs3733631 1.000 rs3796951 chr4:104628158 A/T cg24090629 chr4:104641072 TACR3 0.73 5.81 0.46 4.96e-8 Menarche (age at onset); TGCT trans rs11098499 0.954 rs12510138 chr4:120423935 C/G cg25214090 chr10:38739885 LOC399744 0.38 6.65 0.51 8.51e-10 Corneal astigmatism; TGCT cis rs12477438 0.501 rs6542868 chr2:99782848 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs9926296 0.548 rs6500439 chr16:89808275 A/C cg04287289 chr16:89883240 FANCA 0.95 12.12 0.74 8.63e-23 Vitiligo; TGCT cis rs1153858 0.945 rs16943246 chr15:45720597 G/A cg14582100 chr15:45693742 SPATA5L1 0.45 5.1 0.42 1.22e-6 Homoarginine levels; TGCT cis rs1005277 0.505 rs10827836 chr10:38215441 A/G cg13531842 chr10:38383804 ZNF37A 0.39 4.58 0.38 1.12e-5 Extrinsic epigenetic age acceleration; TGCT cis rs72781680 0.904 rs72796340 chr2:24143622 T/A cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs7208859 0.673 rs11658435 chr17:29228561 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7824557 0.547 rs6601570 chr8:11079367 G/A cg27411982 chr8:10470053 RP1L1 -0.22 -4.55 -0.38 1.26e-5 Retinal vascular caliber; TGCT cis rs3540 0.597 rs3743409 chr15:91045539 T/A cg22089800 chr15:90895588 ZNF774 -0.76 -7.77 -0.57 2.55e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2243480 0.708 rs13242216 chr7:65898277 T/C cg18252515 chr7:66147081 NA -1.18 -7.56 -0.56 7.99e-12 Diabetic kidney disease; TGCT cis rs6845621 0.901 rs1452552 chr4:18919979 G/A cg12196642 chr4:18937545 NA -0.24 -4.45 -0.37 1.91e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs2290402 0.536 rs12509561 chr4:850701 C/T cg06416060 chr4:1402434 NA 0.32 4.43 0.37 2.01e-5 Type 2 diabetes; TGCT cis rs1005224 0.963 rs2302592 chr14:76129287 C/G cg04684003 chr14:76127793 TTLL5;C14orf1 0.61 5.68 0.45 9.22e-8 Large artery stroke; TGCT cis rs6909279 0.678 rs9479056 chr6:151848899 C/A cg10883421 chr6:151773342 RMND1;C6orf211 -0.49 -4.44 -0.37 1.95e-5 Bone mineral density; TGCT cis rs4304924 0.500 rs12585725 chr13:79220899 C/A cg05295671 chr13:79234353 RNF219 0.78 6.17 0.48 8.8e-9 Large artery stroke; TGCT cis rs9910055 0.659 rs227580 chr17:42223068 C/T cg13607699 chr17:42295918 UBTF -0.56 -5.49 -0.44 2.21e-7 Total body bone mineral density; TGCT cis rs7267979 1.000 rs2500436 chr20:25406366 G/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.87 0.47 3.73e-8 Alzheimer's disease; TGCT cis rs1292048 1 rs1292048 chr17:57955071 A/G cg16369400 chr17:58041258 RNFT1 0.23 4.47 0.37 1.72e-5 Red cell distribution width; TGCT cis rs17741873 0.836 rs4745723 chr10:75603338 T/C cg07699608 chr10:75541558 CHCHD1 0.71 4.82 0.4 4.03e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs9902453 0.791 rs7219163 chr17:28210703 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.9 8.62 0.61 2.66e-14 Coffee consumption (cups per day); TGCT cis rs2594989 0.887 rs9850117 chr3:11571991 C/T cg00170343 chr3:11313890 ATG7 -0.68 -4.91 -0.4 2.8e-6 Circulating chemerin levels; TGCT cis rs17345786 0.861 rs79181492 chr3:101216021 G/A cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs6554196 0.606 rs7663318 chr4:55538880 T/C cg22722822 chr4:54931066 CHIC2 0.59 4.98 0.41 2.09e-6 Monocyte count; TGCT cis rs17401966 0.931 rs4846213 chr1:10399178 A/G cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs2486288 0.586 rs12909625 chr15:45572053 C/A cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.38 -0.44 3.57e-7 Glomerular filtration rate; TGCT cis rs2201728 0.967 rs6532814 chr4:100173968 T/C cg07219303 chr4:100140905 ADH6 -0.35 -5.21 -0.42 7.63e-7 Cardiac Troponin-T levels; TGCT cis rs704 0.605 rs2071379 chr17:26695832 A/G cg10342447 chr17:26645325 TMEM97 -0.61 -6.18 -0.49 8.64e-9 Osteoprotegerin levels; TGCT cis rs2070433 0.706 rs2268524 chr21:47838700 C/T cg04277056 chr21:48021941 S100B 0.31 4.48 0.37 1.67e-5 Lymphocyte counts; TGCT cis rs894734 0.535 rs2366143 chr12:54323256 G/A cg17708016 chr12:54321992 NA 0.66 5.53 0.44 1.81e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); TGCT cis rs2243480 0.901 rs778732 chr7:65822360 C/T cg18252515 chr7:66147081 NA -1.11 -6.62 -0.51 9.81e-10 Diabetic kidney disease; TGCT cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.63 5.12 0.42 1.11e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7666738 0.819 rs13139560 chr4:99081188 C/T cg17366294 chr4:99064904 C4orf37 0.71 5.48 0.44 2.27e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1371867 0.555 rs2861348 chr8:101285074 A/G cg06636551 chr8:101224915 SPAG1 -0.43 -5.95 -0.47 2.58e-8 Atrioventricular conduction; TGCT cis rs7267979 1.000 rs6050562 chr20:25336186 C/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2997447 0.653 rs56134135 chr1:26440718 A/T cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg06873352 chr17:61820015 STRADA 0.58 6.36 0.5 3.51e-9 Prudent dietary pattern; TGCT cis rs11677370 0.561 rs13015012 chr2:3821252 C/G cg17052675 chr2:3827356 NA 0.45 8.02 0.58 6.66e-13 Type 2 diabetes; TGCT cis rs8180040 0.545 rs9311403 chr3:47138878 T/C cg27129171 chr3:47204927 SETD2 0.7 8.55 0.61 3.75e-14 Colorectal cancer; TGCT cis rs4595586 0.545 rs6580895 chr12:39372011 C/T cg10518543 chr12:38710700 ALG10B -0.54 -4.44 -0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs587847 0.737 rs4368128 chr15:37677359 G/T cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs8177253 0.665 rs10935074 chr3:133441692 T/G cg11941060 chr3:133502564 NA -0.26 -5.43 -0.44 2.88e-7 Iron status biomarkers; TGCT cis rs7666738 0.519 rs13136069 chr4:98819568 C/T cg17366294 chr4:99064904 C4orf37 0.65 5.96 0.47 2.39e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11711311 0.869 rs1026364 chr3:113370010 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.71 -6.11 -0.48 1.21e-8 IgG glycosylation; TGCT cis rs9921222 0.585 rs7195617 chr16:376781 A/G cg00101154 chr16:420108 MRPL28 0.53 5.67 0.45 9.45e-8 Bone mineral density (spine);Bone mineral density; TGCT cis rs7017914 0.967 rs34558600 chr8:71586152 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs2229238 0.911 rs4639752 chr1:154508974 T/A cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs12971120 0.891 rs3794955 chr18:72174827 C/T cg25817165 chr18:72167213 CNDP2 -0.27 -4.65 -0.39 8.37e-6 Refractive error; TGCT cis rs7666738 0.570 rs1869351 chr4:99077286 T/C cg18180107 chr4:99064573 C4orf37 0.51 4.56 0.38 1.21e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs3020333 1.000 rs3020332 chr6:152008924 C/T cg22157087 chr6:152012887 ESR1 0.19 4.61 0.38 9.97e-6 Total body bone mineral density; TGCT cis rs1857353 1.000 rs2040079 chr1:75906421 G/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs151997 0.962 rs27475 chr5:50180439 A/C cg06027927 chr5:50259733 NA 0.46 4.61 0.38 9.69e-6 Callous-unemotional behaviour; TGCT cis rs35306767 0.953 rs10904581 chr10:964685 A/T cg26597838 chr10:835615 NA 0.63 9.1 0.63 1.93e-15 Eosinophil percentage of granulocytes; TGCT cis rs514406 0.729 rs534070 chr1:53308858 T/G cg25767906 chr1:53392781 SCP2 -0.63 -7.64 -0.57 5e-12 Monocyte count; TGCT cis rs12148488 0.763 rs2304902 chr15:75340727 G/T cg10253484 chr15:75165896 SCAMP2 -0.57 -4.93 -0.41 2.53e-6 Caffeine consumption; TGCT cis rs1552244 1.000 rs6782602 chr3:10116541 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs4595586 0.545 rs12809435 chr12:39404341 C/T cg10518543 chr12:38710700 ALG10B -0.54 -4.44 -0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs35771425 0.509 rs3120782 chr1:211419700 A/T cg26515805 chr1:211431828 RCOR3 -0.44 -4.78 -0.39 4.87e-6 Educational attainment (years of education); TGCT cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg11941060 chr3:133502564 NA -0.26 -5.27 -0.43 5.95e-7 Iron status biomarkers; TGCT cis rs1775715 0.513 rs2808089 chr10:32145112 A/T cg14930904 chr10:32216787 ARHGAP12 0.53 5.1 0.42 1.22e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg13695892 chr22:41940480 POLR3H -0.9 -9.03 -0.63 2.7e-15 Vitiligo; TGCT cis rs7552404 0.924 rs2173378 chr1:76201992 G/T cg03433033 chr1:76189801 ACADM 0.77 9.25 0.64 8.26e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28735056 1.000 rs3826576 chr18:77633976 G/A cg20368463 chr18:77673604 PQLC1 -0.44 -5.51 -0.44 1.99e-7 Schizophrenia; TGCT cis rs5769765 0.954 rs6009900 chr22:50236610 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.12 -12.25 -0.74 4.22e-23 Schizophrenia; TGCT cis rs611744 0.967 rs597649 chr8:109187718 T/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs6089829 0.962 rs6062776 chr20:61663736 A/G cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg08859206 chr1:53392774 SCP2 -0.43 -6.71 -0.52 6.09e-10 Monocyte count; TGCT cis rs67311347 1.000 rs4973898 chr3:40459532 A/G cg13683864 chr3:40499215 RPL14 1.01 10.31 0.68 2.27e-18 Renal cell carcinoma; TGCT cis rs6964587 0.967 rs6974827 chr7:91772945 C/T cg17063962 chr7:91808500 NA 0.93 10.08 0.67 8.03e-18 Breast cancer; TGCT cis rs9534288 0.797 rs6561278 chr13:46572937 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs57590327 0.555 rs7634258 chr3:81799100 T/C cg07356753 chr3:81810745 GBE1 -0.77 -7.2 -0.54 5.1e-11 Extraversion; TGCT cis rs2645424 0.635 rs62495697 chr8:11709007 G/A cg18999641 chr8:11876646 NA 0.22 4.54 0.38 1.31e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs67311347 1.000 rs7642906 chr3:40492633 G/A cg13683864 chr3:40499215 RPL14 1.07 10.74 0.69 1.99e-19 Renal cell carcinoma; TGCT cis rs7666738 0.830 rs10009206 chr4:99056900 A/C cg05340658 chr4:99064831 C4orf37 -0.51 -5.78 -0.46 5.78e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3087591 0.960 rs2952999 chr17:29509801 G/T cg24425628 chr17:29625626 OMG;NF1 0.47 7.11 0.54 8e-11 Hip circumference; TGCT cis rs1348850 0.914 rs2364854 chr2:178378452 T/A cg22681709 chr2:178499509 PDE11A -0.35 -4.67 -0.39 7.69e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7917772 0.532 rs10748829 chr10:104527244 G/A cg05855489 chr10:104503620 C10orf26 0.66 5.24 0.43 6.74e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7674212 1.000 rs7674212 chr4:103988899 G/T cg16532752 chr4:104119610 CENPE -0.53 -5.03 -0.41 1.7e-6 Type 2 diabetes; TGCT cis rs16866061 1.000 rs72974267 chr2:225454209 T/C cg12698349 chr2:225449008 CUL3 1.02 9.8 0.66 3.83e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs67311347 1.000 rs6599094 chr3:40399593 A/G cg17264618 chr3:40429014 ENTPD3 0.31 4.65 0.39 8.38e-6 Renal cell carcinoma; TGCT cis rs4622507 0.688 rs4784464 chr16:55073590 T/C cg27642062 chr16:55513148 MMP2 -0.65 -4.68 -0.39 7.52e-6 Social communication problems; TGCT cis rs9303401 0.614 rs34678056 chr17:57177549 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.64 5.87 0.47 3.79e-8 Cognitive test performance; TGCT cis rs7219021 0.705 rs999475 chr17:46988044 C/T cg26022315 chr17:47021804 SNF8 -0.54 -4.65 -0.39 8.2e-6 Schizophrenia or bipolar disorder; TGCT cis rs7086627 0.515 rs10887900 chr10:82210265 A/G cg01528321 chr10:82214614 TSPAN14 0.61 5.74 0.46 6.72e-8 Post bronchodilator FEV1; TGCT cis rs11190604 1.000 rs1106565 chr10:102211613 T/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2404602 0.692 rs59088060 chr15:76859974 T/C cg22467129 chr15:76604101 ETFA -0.47 -5.43 -0.44 2.87e-7 Blood metabolite levels; TGCT cis rs10751667 1.000 rs7396798 chr11:970510 G/T cg06064525 chr11:970664 AP2A2 -0.33 -6.51 -0.5 1.71e-9 Alzheimer's disease (late onset); TGCT cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg17345569 chr6:42928274 GNMT -0.48 -4.96 -0.41 2.29e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs56036086 1.000 rs73187249 chr22:50634526 G/A cg01548456 chr22:50352384 NA 0.37 4.82 0.4 4.17e-6 Platelet count;Plateletcrit; TGCT cis rs11247915 0.600 rs72649360 chr1:26662904 C/T cg23732845 chr1:26663426 AIM1L -0.38 -4.8 -0.4 4.4e-6 Obesity-related traits; TGCT cis rs6840360 0.550 rs62327349 chr4:152627230 G/C cg17479576 chr4:152424074 FAM160A1 -0.66 -6.63 -0.51 9.17e-10 Intelligence (multi-trait analysis); TGCT cis rs875971 0.767 rs1643394 chr7:65836094 A/G cg11764359 chr7:65958608 NA 0.58 5.31 0.43 4.91e-7 Aortic root size; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.42 4.65 0.39 8.34e-6 Lymphocyte counts; TGCT cis rs36051895 0.589 rs10283734 chr9:5217139 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.36 -0.64 4.53e-16 Pediatric autoimmune diseases; TGCT cis rs35883536 0.647 rs1335765 chr1:101048612 A/T cg10298815 chr1:101004474 GPR88 -0.25 -4.5 -0.37 1.54e-5 Monocyte count; TGCT cis rs2120019 0.567 rs8029351 chr15:75177237 A/C cg09165964 chr15:75287851 SCAMP5 -0.88 -7.07 -0.54 9.73e-11 Blood trace element (Zn levels); TGCT cis rs896854 0.738 rs509594 chr8:95967156 C/G cg16049864 chr8:95962084 TP53INP1 0.65 7.67 0.57 4.37e-12 Type 2 diabetes; TGCT cis rs4273100 0.749 rs7221299 chr17:19250679 G/A cg01534423 chr17:18965556 NA 0.9 5.1 0.42 1.22e-6 Schizophrenia; TGCT cis rs6089829 1.000 rs6089828 chr20:61668998 C/T cg08564027 chr20:61660810 NA 0.38 6.77 0.52 4.65e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7698623 0.850 rs4693195 chr4:88798211 G/A cg27387453 chr4:88533842 DSPP -0.6 -4.53 -0.38 1.37e-5 Cardiovascular disease risk factors; TGCT cis rs9291683 0.595 rs11722930 chr4:10035454 G/A cg00071950 chr4:10020882 SLC2A9 0.68 8.84 0.62 7.71e-15 Bone mineral density; TGCT cis rs9388451 0.903 rs9388446 chr6:126064920 T/A cg05901451 chr6:126070800 HEY2 -1.01 -13.78 -0.78 9.03e-27 Brugada syndrome; TGCT cis rs2762353 0.603 rs9393670 chr6:25789061 A/G cg03517284 chr6:25882590 NA 0.54 5.44 0.44 2.77e-7 Blood metabolite levels; TGCT cis rs2730245 0.527 rs2036582 chr7:158701708 A/T cg11984989 chr7:158649758 WDR60 0.91 7.29 0.55 3.16e-11 Height; TGCT cis rs11190604 1.000 rs7085439 chr10:102210100 C/T cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3741404 0.620 rs12787945 chr11:63977546 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 8.19 0.59 2.77e-13 Platelet count; TGCT cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg18252515 chr7:66147081 NA 1.22 7.33 0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs13256369 0.802 rs11995449 chr8:8559898 G/A cg17143192 chr8:8559678 CLDN23 0.53 4.82 0.4 4.03e-6 Obesity-related traits; TGCT cis rs7959452 0.535 rs7133487 chr12:69774377 G/A cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs4699052 0.963 rs6533078 chr4:104212156 C/T cg16532752 chr4:104119610 CENPE -0.56 -5.1 -0.42 1.26e-6 Testicular germ cell tumor; TGCT cis rs8103278 1.000 rs8109951 chr19:46289503 C/T cg14061069 chr19:46274453 DMPK -0.43 -6.19 -0.49 8.07e-9 Coronary artery disease; TGCT cis rs2878628 0.650 rs56098033 chr3:52758571 T/A cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.627 rs4407265 chr2:101005846 C/G cg14675211 chr2:100938903 LONRF2 0.47 4.56 0.38 1.22e-5 Intelligence (multi-trait analysis); TGCT cis rs9914988 0.943 rs11651867 chr17:27147248 T/G cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9788333 0.962 rs34853044 chr13:21883784 C/T cg04632378 chr13:21900426 NA 0.43 5.04 0.41 1.6e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs597539 0.652 rs482172 chr11:68668437 C/A cg21963583 chr11:68658836 MRPL21 0.36 6.04 0.48 1.7e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs910316 0.810 rs77939209 chr14:75670070 A/G cg23033748 chr14:75592666 NEK9 -0.26 -4.49 -0.37 1.6e-5 Height; TGCT cis rs7847628 0.587 rs4837796 chr9:123610288 A/G cg14255062 chr9:123606675 PSMD5;LOC253039 -0.22 -5.51 -0.44 1.98e-7 Birth weight; TGCT cis rs6951245 0.580 rs77101766 chr7:1122438 A/G cg09177884 chr7:1199841 ZFAND2A -0.7 -5.52 -0.44 1.92e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs908922 0.676 rs12116609 chr1:152497685 C/T cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.26e-9 Hair morphology; TGCT cis rs7617773 0.815 rs6793150 chr3:48351560 G/A cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs6598955 0.671 rs3924325 chr1:26616320 T/C cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs6912958 0.582 rs242285 chr6:88070743 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.44 5.83 0.46 4.53e-8 Monocyte percentage of white cells; TGCT cis rs40363 0.645 rs6501177 chr16:3523681 C/T cg05754148 chr16:3507555 NAT15 0.43 5.14 0.42 1.02e-6 Tuberculosis; TGCT cis rs6089829 0.643 rs6011545 chr20:61660038 G/A cg18188782 chr20:61659543 NA 0.41 4.45 0.37 1.91e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs7223966 1.000 rs8069687 chr17:61883023 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.58 -4.63 -0.38 8.91e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs11674184 0.516 rs72772088 chr2:11742458 A/G cg07314298 chr2:11723111 GREB1 -0.38 -6.85 -0.52 3.13e-10 Endometriosis; TGCT cis rs244731 0.959 rs6872021 chr5:176610012 G/A cg06060754 chr5:176797920 RGS14 -0.44 -6.2 -0.49 7.79e-9 Urate levels in lean individuals; TGCT cis rs11190604 1.000 rs10883511 chr10:102299407 A/G cg23241863 chr10:102295624 HIF1AN 0.72 5.33 0.43 4.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12478296 0.901 rs9653611 chr2:243006956 C/G cg06360820 chr2:242988706 NA -0.62 -5.23 -0.43 6.93e-7 Obesity-related traits; TGCT cis rs9914988 0.887 rs4795463 chr17:27146389 G/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT trans rs7613875 0.620 rs13079006 chr3:49996924 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.32 0.6 1.31e-13 Body mass index; TGCT cis rs2762353 0.808 rs1184803 chr6:25834658 T/C cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.23e-9 Blood metabolite levels; TGCT cis rs13256369 1.000 rs4841017 chr8:8577093 A/G cg17143192 chr8:8559678 CLDN23 0.62 5.83 0.46 4.47e-8 Obesity-related traits; TGCT cis rs4689388 0.791 rs1046317 chr4:6304242 T/C cg25554036 chr4:6271136 WFS1 0.54 6.41 0.5 2.79e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs8078723 0.866 rs7502514 chr17:38188844 A/G cg17467752 chr17:38218738 THRA -0.63 -6.18 -0.49 8.61e-9 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs35306767 0.903 rs11253495 chr10:937064 C/T cg20503657 chr10:835505 NA 0.73 9.92 0.67 1.92e-17 Eosinophil percentage of granulocytes; TGCT trans rs1908814 0.510 rs57655799 chr8:11782417 A/C cg15556689 chr8:8085844 FLJ10661 0.8 7.57 0.56 7.56e-12 Neuroticism; TGCT cis rs4455778 0.665 rs3925006 chr7:49068450 G/C cg26309511 chr7:48887640 NA 0.47 5.33 0.43 4.56e-7 Lung cancer in never smokers; TGCT cis rs7267979 1.000 rs2258884 chr20:25279539 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs707040 0.961 rs2882047 chr2:155235000 G/T cg18104148 chr2:154337490 NA 0.19 4.56 0.38 1.2e-5 Sudden cardiac arrest; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg06753367 chr22:24256600 NA -0.24 -4.5 -0.37 1.56e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1129187 0.755 rs13215983 chr6:42924193 C/T cg13397359 chr6:42928475 GNMT 0.73 6.54 0.51 1.45e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs3749237 0.595 rs4855861 chr3:49525962 G/T cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs11031096 0.678 rs12292724 chr11:4176671 T/A cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.758 rs532242 chr1:53308665 C/G cg08859206 chr1:53392774 SCP2 -0.42 -6.22 -0.49 7.06e-9 Monocyte count; TGCT cis rs4285028 0.747 rs1920299 chr3:121593769 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.74 6.3 0.49 4.77e-9 Multiple sclerosis; TGCT cis rs861020 0.606 rs4844903 chr1:210006267 C/T cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs4862750 0.872 rs6825289 chr4:187879109 T/G cg03452623 chr4:187889614 NA -0.37 -5.53 -0.44 1.84e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg14983838 chr19:29218262 NA 0.83 6.85 0.52 3.07e-10 Methadone dose in opioid dependence; TGCT cis rs2354432 0.607 rs2353999 chr1:146830686 T/C cg25205988 chr1:146714368 CHD1L -1.37 -6.13 -0.48 1.1e-8 Mitochondrial DNA levels; TGCT cis rs6938 0.534 rs12907898 chr15:75207872 C/T cg09165964 chr15:75287851 SCAMP5 0.54 5.07 0.41 1.39e-6 Breast cancer; TGCT cis rs6964587 1.000 rs10274756 chr7:91740796 G/A cg17063962 chr7:91808500 NA 0.87 9.34 0.64 4.87e-16 Breast cancer; TGCT cis rs73001065 0.688 rs59148799 chr19:19484008 A/G cg03709012 chr19:19516395 GATAD2A 0.88 4.69 0.39 7.11e-6 LDL cholesterol; TGCT trans rs208520 0.661 rs6937856 chr6:66867468 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs10193935 0.901 rs72798529 chr2:42537471 C/T cg27598129 chr2:42591480 NA -0.4 -5.51 -0.44 1.98e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs208520 1.000 rs12209225 chr6:66996443 G/T cg07460842 chr6:66804631 NA 0.8 6.98 0.53 1.61e-10 Exhaled nitric oxide output; TGCT cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs10504229 0.683 rs61241336 chr8:58106585 A/G cg02725872 chr8:58115012 NA -0.41 -5.38 -0.44 3.5e-7 Developmental language disorder (linguistic errors); TGCT cis rs2576037 0.583 rs4890698 chr18:44489725 A/G cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.57 -0.38 1.18e-5 Personality dimensions; TGCT cis rs714052 0.518 rs13234378 chr7:73026151 A/T cg14087351 chr7:73037990 MLXIPL -0.81 -5.58 -0.45 1.47e-7 Hypertriglyceridemia;Triglycerides; TGCT cis rs9910055 0.529 rs228746 chr17:42173752 T/C cg13607699 chr17:42295918 UBTF -0.63 -5.14 -0.42 1.04e-6 Total body bone mineral density; TGCT cis rs9383153 0.793 rs9358090 chr6:16348728 G/A cg06493612 chr6:15502050 JARID2 0.62 4.92 0.4 2.74e-6 Gambling; TGCT trans rs7618501 0.699 rs2681780 chr3:49897830 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.93 10.31 0.68 2.22e-18 Intelligence (multi-trait analysis); TGCT cis rs1990950 0.692 rs10054988 chr5:156859483 T/G cg25387487 chr5:157003181 ADAM19 0.31 4.78 0.39 4.78e-6 Lung function (FEV1/FVC); TGCT cis rs10114408 0.959 rs10821258 chr9:96657324 C/T cg13679303 chr9:96623674 NA -0.36 -4.62 -0.38 9.52e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs16958440 0.867 rs10083937 chr18:44695602 A/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs611744 0.967 rs598022 chr8:109187759 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs11696501 0.694 rs1487325 chr20:44258989 A/G cg11783356 chr20:44313418 WFDC10B 0.32 4.63 0.38 9.25e-6 Brain structure; TGCT cis rs7726839 0.574 rs11134148 chr5:637107 C/T cg16624210 chr5:671434 TPPP 0.42 4.68 0.39 7.38e-6 Obesity-related traits; TGCT cis rs7618915 0.547 rs11130313 chr3:52676190 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs600231 0.665 rs12790095 chr11:65326086 T/G cg17120908 chr11:65337727 SSSCA1 -0.52 -4.79 -0.39 4.76e-6 Bone mineral density; TGCT cis rs7666738 0.830 rs4699590 chr4:98974030 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.547 rs4368210 chr17:17896090 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.78 -8.1 -0.59 4.3e-13 Total body bone mineral density; TGCT cis rs11190604 1.000 rs10883492 chr10:102206089 G/A cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9638182 0.673 rs13233571 chr7:72971231 C/T cg14087351 chr7:73037990 MLXIPL -0.65 -4.88 -0.4 3.18e-6 Triglycerides; TGCT cis rs394563 0.591 rs237016 chr6:149744859 T/C cg03678062 chr6:149772716 ZC3H12D -0.36 -4.55 -0.38 1.27e-5 Dupuytren's disease; TGCT cis rs1062177 1.000 rs6890099 chr5:151151962 A/G cg12924095 chr5:151150029 G3BP1 0.35 5.09 0.42 1.31e-6 Preschool internalizing problems; TGCT cis rs11935103 0.636 rs1470752 chr4:187296170 T/C cg16785698 chr4:186456103 PDLIM3 0.44 4.47 0.37 1.74e-5 Response to citalopram treatment; TGCT cis rs6435862 0.636 rs717548 chr2:215676905 G/A cg04004882 chr2:215674386 BARD1 -0.75 -6.65 -0.51 8.39e-10 Neuroblastoma (high-risk); TGCT cis rs2235642 0.821 rs8051895 chr16:1602811 A/G cg07639376 chr16:1584516 IFT140;TMEM204 -0.33 -5.85 -0.46 4.15e-8 Coronary artery disease; TGCT cis rs7820838 0.510 rs6468120 chr8:32402094 T/C cg22651812 chr8:32095135 NRG1 -0.22 -4.56 -0.38 1.21e-5 Post bronchodilator FEV1/FVC ratio in COPD;Lung cancer; TGCT cis rs10504229 0.683 rs66893068 chr8:58144238 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg15242686 chr22:24348715 GSTTP1 -0.42 -5.68 -0.45 9.1e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs853679 0.517 rs9468292 chr6:28095355 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs3785574 0.886 rs62077504 chr17:61837734 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.73 0.46 7.09e-8 Height; TGCT cis rs739496 0.653 rs7956676 chr12:112191139 A/G cg10833066 chr12:111807467 FAM109A 0.35 5.18 0.42 8.83e-7 Platelet count; TGCT cis rs1156327 0.510 rs4617845 chr16:19325209 A/G cg02978544 chr16:19716338 NA -0.42 -4.46 -0.37 1.82e-5 Periodontal disease-related phenotypes; TGCT cis rs1372520 0.684 rs2583963 chr4:90727088 C/T cg26578617 chr4:90757533 SNCA -0.52 -4.44 -0.37 1.99e-5 Neuroticism; TGCT cis rs3772130 0.775 rs6781857 chr3:121560721 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.62 0.38 9.48e-6 Cognitive performance; TGCT cis rs250677 0.687 rs250671 chr5:148446523 T/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs6866344 0.570 rs11740283 chr5:178136440 T/C cg10224037 chr5:178157518 ZNF354A 0.98 9.45 0.65 2.77e-16 Neutrophil percentage of white cells; TGCT cis rs11955175 0.717 rs41271053 chr5:40835393 A/C cg17351974 chr5:40835760 RPL37 0.87 5.92 0.47 2.98e-8 Bipolar disorder and schizophrenia; TGCT cis rs12510870 0.634 rs12510629 chr4:74380330 G/A cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs6089584 0.889 rs6142923 chr20:60596617 C/T cg13665807 chr20:60559372 TAF4 0.47 5.04 0.41 1.62e-6 Body mass index; TGCT cis rs7924176 0.521 rs10824137 chr10:76033154 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.47 4.57 0.38 1.15e-5 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs2115630 0.691 rs61322921 chr15:85163638 T/C cg17173187 chr15:85201210 NMB -0.47 -5.85 -0.47 4.06e-8 P wave terminal force; TGCT cis rs2439831 0.867 rs2251844 chr15:43836478 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.97 7.38 0.55 2.03e-11 Lung cancer in ever smokers; TGCT cis rs6429082 0.755 rs291372 chr1:235694106 G/C cg26050004 chr1:235667680 B3GALNT2 0.64 5.79 0.46 5.53e-8 Adiposity; TGCT cis rs67311347 1.000 rs17078511 chr3:40396254 A/G cg13683864 chr3:40499215 RPL14 -1.1 -11.79 -0.73 5.64e-22 Renal cell carcinoma; TGCT cis rs6752107 0.967 rs10203952 chr2:234153366 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 5.0 0.41 1.87e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs8103278 1.000 rs7256192 chr19:46338492 G/A cg14061069 chr19:46274453 DMPK -0.44 -6.29 -0.49 4.97e-9 Coronary artery disease; TGCT cis rs2050392 1.000 rs2183176 chr10:30698544 C/T cg13289132 chr10:30722225 MAP3K8 0.37 4.71 0.39 6.64e-6 Inflammatory bowel disease; TGCT cis rs7772486 0.875 rs2748483 chr6:146335560 A/T cg23711669 chr6:146136114 FBXO30 -0.83 -9.07 -0.63 2.2e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2228479 0.867 rs12930056 chr16:89946649 C/A cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs7000551 0.725 rs4871998 chr8:22308150 A/T cg12081754 chr8:22256438 SLC39A14 0.3 5.0 0.41 1.93e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs17102423 0.826 rs10873180 chr14:65604361 A/G cg11161011 chr14:65562177 MAX 0.49 6.85 0.52 3.13e-10 Obesity-related traits; TGCT cis rs2429030 0.901 rs2245565 chr10:70759180 T/G cg12938159 chr10:71332776 NEUROG3 -0.36 -4.48 -0.37 1.68e-5 Schizophrenia; TGCT cis rs2836950 0.565 rs2836934 chr21:40564885 A/C cg11890956 chr21:40555474 PSMG1 -0.68 -6.78 -0.52 4.39e-10 Menarche (age at onset); TGCT cis rs2070488 0.804 rs13059256 chr3:38504315 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.79 7.9 0.58 1.3e-12 Electrocardiographic conduction measures; TGCT cis rs61884328 0.852 rs61897782 chr11:47150177 G/A cg13308137 chr11:47528955 CUGBP1 0.38 4.47 0.37 1.76e-5 Total body bone mineral density (age over 60); TGCT cis rs769267 0.930 rs4808959 chr19:19572108 T/G cg03709012 chr19:19516395 GATAD2A 0.75 6.24 0.49 6.45e-9 Tonsillectomy; TGCT cis rs7072216 0.691 rs3829853 chr10:100171174 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs344364 0.511 rs1657132 chr16:1949924 C/T cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs36051895 0.603 rs10123980 chr9:5130363 T/C cg02405213 chr9:5042618 JAK2 -0.76 -10.6 -0.69 4.38e-19 Pediatric autoimmune diseases; TGCT cis rs7666738 0.830 rs10011009 chr4:98981749 G/A cg18180107 chr4:99064573 C4orf37 0.53 4.89 0.4 3.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7552404 0.727 rs11161626 chr1:76260837 C/T cg10523679 chr1:76189770 ACADM 0.73 6.77 0.52 4.67e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs5769765 0.658 rs2157536 chr22:50190180 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.32 4.51 0.38 1.49e-5 Schizophrenia; TGCT cis rs6121246 0.528 rs6060252 chr20:30191084 A/G cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs4929949 0.902 rs61875898 chr11:8627224 C/A cg14521421 chr11:8862019 ST5 -0.3 -4.62 -0.38 9.42e-6 Body mass index; TGCT cis rs8067545 1.000 rs9891739 chr17:19942177 C/T cg13482628 chr17:19912719 NA 0.54 4.73 0.39 5.94e-6 Schizophrenia; TGCT cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg04317338 chr11:64019027 PLCB3 0.77 6.43 0.5 2.48e-9 Mean platelet volume; TGCT cis rs7707921 0.522 rs10070637 chr5:81490608 A/G cg15871215 chr5:81402204 ATG10 0.25 4.97 0.41 2.22e-6 Breast cancer; TGCT cis rs6671200 0.831 rs79662819 chr1:95619804 C/T cg20701556 chr1:95698924 RWDD3 0.57 4.49 0.37 1.62e-5 Stearic acid (18:0) levels; TGCT cis rs28735056 0.967 rs11662248 chr18:77619009 C/T cg20368463 chr18:77673604 PQLC1 -0.44 -5.42 -0.44 2.99e-7 Schizophrenia; TGCT cis rs34783982 0.748 rs12438134 chr15:89487518 T/A cg26213453 chr15:89455860 MFGE8 0.34 4.64 0.38 8.87e-6 Squamous cell lung carcinoma; TGCT cis rs12478296 1.000 rs56387669 chr2:243043889 T/C cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs17345786 1.000 rs3804775 chr3:101306507 C/T cg11279151 chr3:101281821 RG9MTD1 -0.45 -9.64 -0.65 9.35e-17 Colonoscopy-negative controls vs population controls; TGCT cis rs1334894 0.792 rs56318292 chr6:35531163 C/T cg24281267 chr6:35479648 TULP1 -0.43 -4.47 -0.37 1.78e-5 Coronary artery disease; TGCT cis rs1799949 0.965 rs8176087 chr17:41270666 C/A cg23758822 chr17:41437982 NA 0.72 6.91 0.53 2.23e-10 Menopause (age at onset); TGCT cis rs6582630 0.519 rs1607882 chr12:38361657 G/A cg26384229 chr12:38710491 ALG10B 0.76 6.86 0.52 2.86e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs1215050 0.740 rs783945 chr4:99014394 G/A cg17366294 chr4:99064904 C4orf37 -0.54 -5.86 -0.47 3.98e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6582630 0.560 rs11504462 chr12:38440379 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6060960 0.502 rs6089110 chr20:30486907 A/T cg06102403 chr20:30458708 TTLL9;DUSP15 0.41 5.11 0.42 1.18e-6 Oppositional defiant disorder dimensions in attention-deficit hyperactivity disorder; TGCT cis rs4927850 1.000 rs7630875 chr3:195753766 A/G cg22891161 chr3:195456627 MUC20 -0.24 -5.58 -0.45 1.45e-7 Pancreatic cancer; TGCT cis rs7826238 0.601 rs2979206 chr8:8345581 G/C cg06636001 chr8:8085503 FLJ10661 0.64 5.96 0.47 2.41e-8 Systolic blood pressure; TGCT cis rs1348850 0.567 rs2222711 chr2:178534110 G/T cg22681709 chr2:178499509 PDE11A -0.47 -6.01 -0.47 1.94e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs806215 0.547 rs765971 chr7:127420642 C/T cg11539674 chr7:127291444 SND1 -0.36 -4.6 -0.38 1.02e-5 Type 2 diabetes; TGCT cis rs2070488 0.965 rs3762788 chr3:38493852 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs698813 0.642 rs1837702 chr2:44492444 T/A cg00619915 chr2:44497795 NA -0.24 -5.51 -0.44 1.99e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs10423674 0.526 rs11085241 chr19:18828546 G/A cg20185461 chr19:18899082 COMP -0.53 -5.03 -0.41 1.68e-6 Menarche (age at onset); TGCT cis rs10510102 0.872 rs12265369 chr10:123727970 A/T cg23691251 chr10:123688108 ATE1 -0.59 -4.7 -0.39 6.75e-6 Breast cancer; TGCT cis rs1801251 0.963 rs7591176 chr2:233581803 C/A cg08000102 chr2:233561755 GIGYF2 0.64 6.5 0.5 1.75e-9 Coronary artery disease; TGCT cis rs17473412 1.000 rs76499408 chr5:122711035 G/A cg15125798 chr5:122621645 NA -0.57 -5.13 -0.42 1.08e-6 Total body bone mineral density; TGCT cis rs7666738 0.609 rs28833816 chr4:98868866 T/C cg18180107 chr4:99064573 C4orf37 0.54 4.54 0.38 1.32e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs1532993 0.518 rs11097567 chr4:98597987 T/C cg05340658 chr4:99064831 C4orf37 -0.38 -4.49 -0.37 1.59e-5 Post bronchodilator FEV1/FVC ratio; TGCT cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9534288 0.912 rs2404732 chr13:46618611 C/A cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg20007245 chr22:24372913 LOC391322 0.7 6.93 0.53 2.09e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9583531 0.760 rs1887200 chr13:111393137 A/C cg24331049 chr13:111365604 ING1 -0.67 -4.88 -0.4 3.21e-6 Coronary artery disease; TGCT cis rs6089584 0.526 rs6061965 chr20:60607858 A/C cg13770153 chr20:60521292 NA -0.41 -5.23 -0.43 6.91e-7 Body mass index; TGCT cis rs1580019 0.587 rs6968990 chr7:32552159 C/T cg06627557 chr7:32535165 LSM5;AVL9 -1.17 -14.08 -0.78 1.71e-27 Cognitive ability; TGCT cis rs62244186 0.566 rs55852922 chr3:44826188 A/G cg25151919 chr3:44754333 ZNF502 -0.47 -5.44 -0.44 2.78e-7 Depressive symptoms; TGCT cis rs7267979 0.934 rs2261753 chr20:25262291 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12477438 0.798 rs6542848 chr2:99573732 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.21 -0.49 7.35e-9 Chronic sinus infection; TGCT cis rs7208859 0.573 rs8078182 chr17:29149664 C/T cg13385521 chr17:29058706 SUZ12P 0.74 4.5 0.37 1.56e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12188164 0.965 rs72717435 chr5:448202 G/A cg26850624 chr5:429559 AHRR -0.2 -4.77 -0.39 5.02e-6 Cystic fibrosis severity; TGCT cis rs12477438 0.520 rs6717729 chr2:99756941 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.12 17.23 0.84 1.05e-34 Chronic sinus infection; TGCT cis rs9926296 0.605 rs8046243 chr16:89852133 A/G cg04287289 chr16:89883240 FANCA 0.93 11.59 0.72 1.71e-21 Vitiligo; TGCT cis rs6121246 0.529 rs6060296 chr20:30198480 T/C cg21427119 chr20:30132790 HM13 -0.39 -5.61 -0.45 1.25e-7 Mean corpuscular hemoglobin; TGCT cis rs1005277 0.557 rs1854563 chr10:38434961 G/A cg25427524 chr10:38739819 LOC399744 -0.4 -8.23 -0.59 2.17e-13 Extrinsic epigenetic age acceleration; TGCT cis rs28735056 0.933 rs56181785 chr18:77633629 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.58 -0.45 1.47e-7 Schizophrenia; TGCT cis rs2439831 0.681 rs511673 chr15:43618863 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.69 0.62 1.84e-14 Lung cancer in ever smokers; TGCT cis rs11098499 0.691 rs9996494 chr4:120238880 C/A cg09307838 chr4:120376055 NA 0.63 6.14 0.48 1.01e-8 Corneal astigmatism; TGCT cis rs7089973 0.604 rs58587374 chr10:116597572 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs1334894 1.000 rs72913427 chr6:35581803 G/C cg24281267 chr6:35479648 TULP1 -0.43 -4.69 -0.39 7.09e-6 Coronary artery disease; TGCT cis rs2115630 0.967 rs11073702 chr15:85310071 G/A cg17173187 chr15:85201210 NMB -0.39 -4.76 -0.39 5.4e-6 P wave terminal force; TGCT cis rs909674 0.865 rs5757682 chr22:39848259 T/G cg11247378 chr22:39784982 NA -0.72 -8.67 -0.61 2.01e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs765787 0.530 rs11636018 chr15:45539137 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs9660180 0.620 rs34298494 chr1:1663402 A/C cg27541892 chr1:1571801 CDK11B -0.42 -5.55 -0.45 1.65e-7 Body mass index; TGCT cis rs514406 0.505 rs7543239 chr1:53162416 A/G cg16325326 chr1:53192061 ZYG11B 0.85 11.54 0.72 2.24e-21 Monocyte count; TGCT cis rs9902453 0.900 rs9910970 chr17:28478329 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs7666738 0.830 rs7669407 chr4:98750251 G/A cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6598955 0.671 rs11579630 chr1:26612297 C/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs6665290 0.870 rs1045289 chr1:227178713 C/T cg10327440 chr1:227177885 CDC42BPA -1.01 -20.94 -0.88 1.57e-42 Myeloid white cell count; TGCT cis rs10504229 1.000 rs112284078 chr8:58191640 A/G cg21724239 chr8:58056113 NA 0.38 5.14 0.42 1.02e-6 Developmental language disorder (linguistic errors); TGCT cis rs116095464 0.558 rs73029475 chr5:206969 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.7 4.65 0.39 8.29e-6 Breast cancer; TGCT cis rs5750830 0.649 rs5750822 chr22:39826788 C/T cg24399712 chr22:39784796 NA -1.0 -12.1 -0.74 9.99e-23 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.563 rs1737585 chr6:8536594 A/G cg07606381 chr6:8435919 SLC35B3 -0.53 -4.96 -0.41 2.27e-6 Motion sickness; TGCT cis rs2721195 0.845 rs756627 chr8:145737286 G/A cg17328964 chr8:145687451 CYHR1 -0.44 -6.04 -0.48 1.62e-8 Age at first birth; TGCT cis rs7953508 0.506 rs768775 chr12:93968197 T/C cg18151635 chr12:93972918 NA -0.19 -4.52 -0.38 1.41e-5 Pubertal anthropometrics; TGCT cis rs2243480 1.000 rs4718315 chr7:65648541 T/C cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs2242116 1.000 rs1138518 chr3:46944274 T/C cg23352942 chr3:46931381 PTH1R -0.33 -4.81 -0.4 4.35e-6 Birth weight; TGCT cis rs9311474 0.581 rs4687626 chr3:52569098 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 5.17 0.42 9.23e-7 Electroencephalogram traits; TGCT trans rs208520 1.000 rs208529 chr6:66957549 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.87 -8.1 -0.59 4.41e-13 Exhaled nitric oxide output; TGCT cis rs77633900 0.614 rs2439984 chr15:76923917 T/C cg21673338 chr15:77095150 SCAPER -0.49 -4.73 -0.39 6.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs8031584 0.678 rs4779790 chr15:31164595 T/C cg08109568 chr15:31115862 NA -0.38 -5.03 -0.41 1.67e-6 Huntington's disease progression; TGCT cis rs3771570 1.000 rs62193256 chr2:242362168 C/T cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.97e-10 Prostate cancer; TGCT cis rs2072499 0.750 rs72708291 chr1:156177285 A/T cg24450063 chr1:156163899 SLC25A44 1.09 10.11 0.67 6.85e-18 Testicular germ cell tumor; TGCT cis rs6964587 1.000 rs34548928 chr7:91668365 G/A cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs1799949 1.000 rs915945 chr17:41179864 C/T cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs617219 0.698 rs72764988 chr5:78533584 G/C cg09550809 chr5:78407562 BHMT 0.4 5.49 0.44 2.19e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs804280 0.662 rs804283 chr8:11611043 G/A cg26752888 chr8:11627280 NEIL2 -0.69 -5.46 -0.44 2.53e-7 Myopia (pathological); TGCT cis rs13191362 1.000 rs13209100 chr6:163159350 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.64 5.62 0.45 1.22e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6671200 1.000 rs35143903 chr1:95622527 C/T cg26537280 chr1:95699037 RWDD3 0.69 5.46 0.44 2.47e-7 Stearic acid (18:0) levels; TGCT trans rs1908814 0.516 rs13281077 chr8:11794814 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs477895 1.000 rs1047206 chr11:64089216 C/G cg23719950 chr11:63933701 MACROD1 -0.59 -4.6 -0.38 1.01e-5 Mean platelet volume; TGCT cis rs2439831 0.850 rs12101756 chr15:44053887 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs2153535 0.580 rs1319169 chr6:8464456 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9902453 0.967 rs8072664 chr17:28333385 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.59 -0.51 1.12e-9 Coffee consumption (cups per day); TGCT cis rs1218582 0.744 rs6674853 chr1:154892753 G/C cg24250549 chr1:154909240 PMVK 0.55 5.27 0.43 5.92e-7 Prostate cancer; TGCT cis rs2458413 0.935 rs2514667 chr8:105358590 C/T cg13045555 chr8:105342365 NA 0.42 6.91 0.53 2.22e-10 Paget's disease; TGCT cis rs7264396 0.676 rs6060730 chr20:34558503 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs7399018 1.000 rs7399018 chr12:51610365 C/T cg25754956 chr12:51612065 POU6F1 -0.77 -7.03 -0.53 1.19e-10 Cisplatin-induced ototoxicity; TGCT cis rs7439150 0.955 rs57292098 chr4:155481006 C/T cg22130008 chr4:155548532 NA -0.44 -5.59 -0.45 1.36e-7 Fibrinogen levels; TGCT cis rs4819052 0.851 rs914218 chr21:46698445 G/C cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg07424592 chr7:64974309 NA 1.26 8.11 0.59 4.17e-13 Diabetic kidney disease; TGCT cis rs875971 0.929 rs12535036 chr7:65964063 G/T cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs796364 0.662 rs11687313 chr2:201146399 G/A cg17644776 chr2:200775616 C2orf69 -0.37 -5.05 -0.41 1.54e-6 Schizophrenia; TGCT cis rs12887734 0.569 rs66953418 chr14:104271470 G/A cg26031613 chr14:104095156 KLC1 -0.71 -6.2 -0.49 7.82e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.679 rs12375285 chr8:58040084 G/A cg08219700 chr8:58056026 NA 0.29 4.5 0.37 1.54e-5 Developmental language disorder (linguistic errors); TGCT cis rs7584330 0.737 rs13397017 chr2:238361241 G/A cg14458575 chr2:238380390 NA 0.51 8.09 0.59 4.69e-13 Prostate cancer; TGCT cis rs67311347 1.000 rs4246666 chr3:40407670 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs73110464 0.609 rs727266 chr12:53356411 C/T cg05393297 chr12:53359155 NA -0.79 -8.43 -0.6 7.2e-14 Cancer (pleiotropy); TGCT cis rs60871478 0.636 rs10245785 chr7:894422 T/C cg00475322 chr7:917719 C7orf20 0.5 4.87 0.4 3.37e-6 Cerebrospinal P-tau181p levels; TGCT cis rs2760061 0.626 rs2796057 chr1:228124414 G/C cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs7954584 0.531 rs6486781 chr12:122318985 A/C cg10207240 chr12:122356781 WDR66 0.33 4.51 0.38 1.46e-5 Mean corpuscular volume; TGCT cis rs9916302 0.706 rs6503521 chr17:37715551 A/C cg07936489 chr17:37558343 FBXL20 0.81 6.02 0.48 1.85e-8 Glomerular filtration rate (creatinine); TGCT cis rs17712049 1.000 rs17712049 chr7:48266195 A/G cg16849860 chr7:48352531 ABCA13 -0.32 -4.93 -0.4 2.57e-6 Refractive astigmatism; TGCT cis rs453301 0.568 rs13281377 chr8:8811564 C/T cg15556689 chr8:8085844 FLJ10661 0.7 5.68 0.45 9.28e-8 Joint mobility (Beighton score); TGCT cis rs3733585 0.699 rs4339211 chr4:9947658 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.42 -0.55 1.62e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4509693 1.000 rs4917908 chr10:102502674 G/C cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT trans rs1814175 0.708 rs10839464 chr11:49981386 T/C cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs9611565 0.559 rs5751160 chr22:42175695 A/G cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT cis rs17221829 0.673 rs4491227 chr11:89403759 G/A cg02982614 chr11:89391479 FOLH1B -0.28 -4.67 -0.39 7.81e-6 Anxiety in major depressive disorder; TGCT cis rs68170813 0.559 rs74898466 chr7:107053998 C/A cg02696742 chr7:106810147 HBP1 -0.7 -5.68 -0.45 8.91e-8 Coronary artery disease; TGCT cis rs8031584 0.678 rs798086 chr15:31129211 C/G cg08704250 chr15:31115839 NA 0.45 6.56 0.51 1.3e-9 Huntington's disease progression; TGCT cis rs8017423 0.586 rs2896134 chr14:90831293 G/A cg04374321 chr14:90722782 PSMC1 -0.58 -5.74 -0.46 6.9e-8 Mortality in heart failure; TGCT cis rs13256369 0.851 rs13254997 chr8:8563753 G/C cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs6754311 0.731 rs2322660 chr2:136557319 A/G cg07169764 chr2:136633963 MCM6 0.61 5.59 0.45 1.35e-7 Mosquito bite size; TGCT cis rs4272321 1 rs4272321 chr7:157951835 A/G cg06715136 chr7:158046025 PTPRN2 0.39 5.69 0.45 8.71e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2463822 1.000 rs2513749 chr11:62105391 C/T cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs6952808 0.542 rs10243920 chr7:1950385 G/A cg04267008 chr7:1944627 MAD1L1 -0.36 -4.6 -0.38 1.03e-5 Bipolar disorder and schizophrenia; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg26516362 chr5:178986906 RUFY1 0.44 4.93 0.4 2.57e-6 Lung cancer; TGCT cis rs6088590 0.965 rs6120727 chr20:33374102 T/C cg06115741 chr20:33292138 TP53INP2 0.66 5.51 0.44 2.01e-7 Coronary artery disease; TGCT cis rs4242434 0.819 rs55776566 chr8:22469492 T/C cg03733263 chr8:22462867 KIAA1967 1.08 17.0 0.84 3.37e-34 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs155076 1.000 rs261430 chr13:21865242 C/T cg11317459 chr13:21872234 NA -1.32 -10.89 -0.7 8.4e-20 White matter hyperintensity burden; TGCT cis rs875971 1.000 rs11974264 chr7:65647582 C/G cg11764359 chr7:65958608 NA -0.6 -5.32 -0.43 4.68e-7 Aortic root size; TGCT cis rs9611519 0.929 rs4820425 chr22:41431342 C/A cg13695892 chr22:41940480 POLR3H -0.55 -4.66 -0.39 8.05e-6 Neuroticism; TGCT cis rs3796352 0.667 rs9831977 chr3:52854140 T/G cg07884673 chr3:53033167 SFMBT1 0.61 4.98 0.41 2.07e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10504229 1.000 rs61998258 chr8:58192284 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs4808199 1.000 rs12972397 chr19:19562349 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.7 5.07 0.41 1.41e-6 Nonalcoholic fatty liver disease; TGCT cis rs10504229 1.000 rs17805326 chr8:58169533 A/C cg22535103 chr8:58192502 C8orf71 -0.43 -5.28 -0.43 5.64e-7 Developmental language disorder (linguistic errors); TGCT cis rs12477438 0.765 rs6754843 chr2:99680485 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs137699 0.652 rs137707 chr22:39751401 T/C cg05872129 chr22:39784769 NA -0.73 -5.62 -0.45 1.2e-7 IgG glycosylation; TGCT cis rs941873 0.803 rs5015119 chr10:81101609 G/C cg09469691 chr10:81107165 PPIF 0.53 5.29 0.43 5.38e-7 Height; TGCT cis rs7744392 0.557 rs9296148 chr6:35337467 G/A cg06087101 chr6:35551932 FKBP5 0.61 4.56 0.38 1.21e-5 Cataracts in type 2 diabetes; TGCT cis rs425277 0.606 rs262664 chr1:2083537 G/C cg24578937 chr1:2090814 PRKCZ 0.26 6.95 0.53 1.8e-10 Height; TGCT cis rs1218582 0.772 rs12069356 chr1:154849771 C/T cg09359103 chr1:154839909 KCNN3 -0.67 -13.37 -0.77 8.58e-26 Prostate cancer; TGCT cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg09904177 chr6:26538194 HMGN4 0.66 6.3 0.49 4.64e-9 Intelligence (multi-trait analysis); TGCT cis rs7209700 0.742 rs7217710 chr17:45370582 C/T cg21624342 chr17:45890973 OSBPL7 -0.2 -5.37 -0.43 3.71e-7 IgG glycosylation; TGCT cis rs9303401 0.580 rs34076823 chr17:57114497 C/G cg25039879 chr17:56429692 SUPT4H1 0.57 5.14 0.42 1.03e-6 Cognitive test performance; TGCT cis rs9902453 0.935 rs4310926 chr17:28433275 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.82 7.98 0.58 8.56e-13 Coffee consumption (cups per day); TGCT cis rs2033711 0.870 rs7409473 chr19:58939165 A/G cg13877915 chr19:58951672 ZNF132 0.89 11.16 0.71 1.92e-20 Uric acid clearance; TGCT cis rs116095464 0.558 rs34629844 chr5:200829 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.72 4.62 0.38 9.36e-6 Breast cancer; TGCT cis rs9733 0.596 rs11807058 chr1:150640475 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs6981523 0.553 rs11783045 chr8:11056175 A/G cg21775007 chr8:11205619 TDH -0.48 -4.46 -0.37 1.81e-5 Neuroticism; TGCT cis rs1218582 0.772 rs877343 chr1:154910012 A/G cg06221963 chr1:154839813 KCNN3 -0.71 -11.67 -0.72 1.1e-21 Prostate cancer; TGCT cis rs56104184 0.775 rs55737338 chr19:49403141 A/G cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6540559 1.000 rs742214 chr1:209960925 T/C cg22029157 chr1:209979665 IRF6 0.76 6.32 0.49 4.37e-9 Cleft lip with or without cleft palate; TGCT cis rs4889855 0.614 rs7221663 chr17:78484166 T/C cg16591659 chr17:78472290 NA -0.35 -5.57 -0.45 1.48e-7 Fractional excretion of uric acid; TGCT cis rs12780845 0.540 rs7096079 chr10:17180675 A/C cg01003015 chr10:17271136 VIM -0.58 -5.4 -0.44 3.26e-7 Homocysteine levels; TGCT cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.42 0.65 3.26e-16 Platelet count; TGCT cis rs6545883 0.794 rs12053388 chr2:61532320 G/A cg15711740 chr2:61764176 XPO1 0.55 4.59 0.38 1.06e-5 Tuberculosis; TGCT cis rs10504229 0.679 rs12375285 chr8:58040084 G/A cg08280861 chr8:58055591 NA 0.4 5.57 0.45 1.49e-7 Developmental language disorder (linguistic errors); TGCT cis rs7226408 0.857 rs17567681 chr18:34481867 A/C cg06757138 chr18:34340585 FHOD3 -0.24 -4.66 -0.39 8.12e-6 Obesity-related traits; TGCT cis rs4845570 0.834 rs13376155 chr1:151721270 A/G cg07092448 chr1:151763213 TDRKH -1.03 -7.53 -0.56 8.99e-12 Coronary artery disease; TGCT cis rs9611565 0.559 rs132768 chr22:42013523 C/A cg06634786 chr22:41940651 POLR3H 0.89 8.56 0.61 3.56e-14 Vitiligo; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg23131131 chr22:24373011 LOC391322 -0.81 -8.74 -0.62 1.33e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11209002 0.614 rs10732837 chr1:67573120 A/G cg02640540 chr1:67518911 SLC35D1 0.59 4.97 0.41 2.18e-6 Crohn's disease; TGCT cis rs2692947 0.526 rs58719199 chr2:96578247 G/A cg23100626 chr2:96804247 ASTL 0.38 4.61 0.38 9.79e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs1499614 0.831 rs3800822 chr7:66147149 A/G cg18252515 chr7:66147081 NA 1.26 7.95 0.58 9.71e-13 Gout; TGCT cis rs7937682 0.889 rs1789361 chr11:111485334 T/C cg09085632 chr11:111637200 PPP2R1B -1.04 -11.23 -0.71 1.28e-20 Primary sclerosing cholangitis; TGCT cis rs3096299 0.738 rs9929606 chr16:89527537 C/T cg06640241 chr16:89574553 SPG7 0.71 7.13 0.54 7.22e-11 Multiple myeloma (IgH translocation); TGCT cis rs7100689 0.784 rs10749578 chr10:82139115 A/G cg01528321 chr10:82214614 TSPAN14 -0.89 -8.97 -0.63 3.94e-15 Post bronchodilator FEV1; TGCT cis rs11085466 1.000 rs4399664 chr19:21778026 C/T cg02997983 chr19:21646781 NA -0.6 -4.6 -0.38 1.03e-5 Colorectal or endometrial cancer; TGCT cis rs7267979 0.966 rs2257461 chr20:25265554 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2153535 0.563 rs3117071 chr6:8537908 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs1218582 0.741 rs11264291 chr1:154914797 C/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.44 -0.56 1.42e-11 Prostate cancer; TGCT cis rs1552244 0.765 rs17050675 chr3:10027686 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.83 5.71 0.46 7.72e-8 Alzheimer's disease; TGCT cis rs9993613 0.756 rs60145670 chr4:73448172 T/C cg15102770 chr4:73434591 ADAMTS3 0.5 4.49 0.37 1.59e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs17345786 0.906 rs55710435 chr3:101180330 G/A cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT trans rs7824557 0.505 rs2736313 chr8:11086942 C/T cg15556689 chr8:8085844 FLJ10661 0.86 8.37 0.6 1.05e-13 Retinal vascular caliber; TGCT cis rs941408 0.890 rs1640269 chr19:2793194 A/C cg06609049 chr19:2785107 THOP1 0.81 7.49 0.56 1.13e-11 Total cholesterol levels; TGCT cis rs16910800 0.638 rs12273883 chr11:23164569 C/G cg20040320 chr11:23191996 NA 0.52 4.51 0.38 1.48e-5 Cancer; TGCT cis rs17030434 1.000 rs75418383 chr4:154719084 A/G cg14289246 chr4:154710475 SFRP2 -0.91 -7.2 -0.54 5.18e-11 Electrocardiographic conduction measures; TGCT cis rs35306767 0.855 rs12781100 chr10:838636 C/T cg20503657 chr10:835505 NA 0.78 11.43 0.72 4.26e-21 Eosinophil percentage of granulocytes; TGCT cis rs13191362 0.935 rs34009353 chr6:163007668 T/G cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7772486 0.790 rs2485632 chr6:146193228 A/G cg05347473 chr6:146136440 FBXO30 0.54 4.98 0.41 2.05e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs10021044 chr4:99002488 A/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs1330939 chr6:146308518 T/A cg23711669 chr6:146136114 FBXO30 0.84 8.85 0.62 7.33e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs4665809 1.000 rs10048683 chr2:26320519 C/T cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs9303401 0.592 rs66583824 chr17:56639853 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs2239547 0.657 rs2071040 chr3:52864860 A/G cg10802521 chr3:52805072 NEK4 -0.64 -6.04 -0.48 1.64e-8 Schizophrenia; TGCT cis rs10504229 0.681 rs11779172 chr8:58045538 A/G cg20607798 chr8:58055168 NA 0.45 4.68 0.39 7.52e-6 Developmental language disorder (linguistic errors); TGCT cis rs7615952 0.932 rs13321217 chr3:125631771 G/A cg05084668 chr3:125655381 ALG1L -0.68 -5.6 -0.45 1.33e-7 Blood pressure (smoking interaction); TGCT cis rs3741151 1.000 rs75007932 chr11:73080336 G/A cg17517138 chr11:73019481 ARHGEF17 0.94 4.71 0.39 6.45e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs250677 0.522 rs12520924 chr5:148349149 C/T cg18129178 chr5:148520854 ABLIM3 0.41 5.06 0.41 1.46e-6 Breast cancer; TGCT cis rs589448 0.535 rs12423794 chr12:69713018 G/A cg11871910 chr12:69753446 YEATS4 0.68 7.13 0.54 7.33e-11 Cerebrospinal fluid biomarker levels; TGCT cis rs6988636 0.792 rs62521803 chr8:124152970 A/C cg27053337 chr8:124217698 FAM83A 0.78 5.42 0.44 3.01e-7 Urinary uromodulin levels; TGCT cis rs9807989 0.729 rs10170583 chr2:102974764 G/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs12579753 0.597 rs2244802 chr12:82153749 C/G cg07988820 chr12:82153109 PPFIA2 0.48 5.37 0.43 3.82e-7 Resting heart rate; TGCT cis rs10875595 0.836 rs62378923 chr5:140656398 C/T cg24830062 chr5:140700576 TAF7 -0.6 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs7666738 0.830 rs10031190 chr4:98908683 C/A cg05340658 chr4:99064831 C4orf37 0.54 6.39 0.5 3.04e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4780401 0.588 rs7205167 chr16:11791057 A/T cg01061890 chr16:11836724 TXNDC11 -0.45 -4.47 -0.37 1.76e-5 Rheumatoid arthritis; TGCT cis rs9868809 0.881 rs13076269 chr3:48675925 T/C cg00383909 chr3:49044727 WDR6 0.93 4.92 0.4 2.68e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9611565 0.921 rs761366 chr22:41744022 C/G cg06481639 chr22:41940642 POLR3H -0.58 -5.2 -0.42 8.04e-7 Vitiligo; TGCT cis rs12477438 0.520 rs11685759 chr2:99766217 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.05 0.63 2.42e-15 Chronic sinus infection; TGCT cis rs2354432 0.505 rs4424556 chr1:146863973 G/C cg25205988 chr1:146714368 CHD1L 1.32 5.88 0.47 3.62e-8 Mitochondrial DNA levels; TGCT cis rs7659604 0.539 rs11098648 chr4:122759872 C/T cg19748678 chr4:122722346 EXOSC9 0.89 8.94 0.63 4.53e-15 Type 2 diabetes; TGCT cis rs7647973 1.000 rs892974 chr3:49398514 C/A cg07636037 chr3:49044803 WDR6 0.72 5.76 0.46 6.38e-8 Menarche (age at onset); TGCT cis rs1577917 0.959 rs16876540 chr6:86612519 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.18 -0.42 8.73e-7 Response to antipsychotic treatment; TGCT cis rs9443189 0.570 rs523465 chr6:76330434 G/C cg01950844 chr6:76311363 SENP6 0.99 6.27 0.49 5.49e-9 Prostate cancer; TGCT cis rs2404602 0.735 rs11857015 chr15:76649390 T/C cg26408565 chr15:76604113 ETFA 0.38 4.47 0.37 1.72e-5 Blood metabolite levels; TGCT cis rs35883536 0.647 rs10875313 chr1:101043057 T/C cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.1e-12 Monocyte count; TGCT cis rs7959452 0.527 rs4761157 chr12:69780907 A/G cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs4704846 0.821 rs35521254 chr5:156526629 T/C cg12943317 chr5:156479607 HAVCR1 -0.3 -4.48 -0.37 1.7e-5 Blood protein levels; TGCT cis rs4824093 0.610 rs77128035 chr22:50241024 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.07 -6.52 -0.51 1.61e-9 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs6674176 0.611 rs3120802 chr1:44386305 C/T cg12908607 chr1:44402522 ARTN -0.71 -4.55 -0.38 1.28e-5 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7043114 0.525 rs10761153 chr9:95130769 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.58 -0.45 1.42e-7 Height; TGCT cis rs9611565 0.559 rs7290991 chr22:41964361 C/G cg03806693 chr22:41940476 POLR3H -1.08 -11.36 -0.71 6.34e-21 Vitiligo; TGCT cis rs2050392 0.517 rs2489847 chr10:30743673 G/A cg18806716 chr10:30721971 MAP3K8 -0.47 -5.56 -0.45 1.61e-7 Inflammatory bowel disease; TGCT cis rs617219 0.698 rs10055956 chr5:78479678 G/A cg23987322 chr5:78407566 BHMT 0.37 4.97 0.41 2.18e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs922182 0.535 rs28729238 chr15:64195152 T/G cg02919090 chr15:64263738 DAPK2 0.34 5.94 0.47 2.67e-8 Blood protein levels; TGCT cis rs9660180 0.868 rs72634846 chr1:1704915 C/G cg13866156 chr1:1669148 SLC35E2 -0.24 -5.87 -0.47 3.74e-8 Body mass index; TGCT cis rs9368481 0.645 rs10456350 chr6:26975581 A/C cg26531700 chr6:26746687 NA 0.56 5.03 0.41 1.67e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7539409 0.651 rs969724 chr1:84300712 T/G cg10977910 chr1:84465055 TTLL7 0.96 5.87 0.47 3.76e-8 Alzheimer's disease; TGCT cis rs968451 0.547 rs738331 chr22:39714216 A/G cg17798944 chr22:39715225 SNORD43;RPL3 0.88 11.02 0.7 4.09e-20 Primary biliary cholangitis; TGCT trans rs2727020 0.701 rs7949044 chr11:49597334 C/T cg15704280 chr7:45808275 SEPT13 -0.64 -6.74 -0.52 5.26e-10 Coronary artery disease; TGCT cis rs10883723 0.810 rs2296589 chr10:104248106 T/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12142240 0.698 rs966907 chr1:46817125 C/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1406084 0.636 rs3910688 chr2:154717147 A/T cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.932 rs12500912 chr4:17603318 C/T cg16339924 chr4:17578868 LAP3 0.76 6.09 0.48 1.28e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7772486 0.720 rs6901888 chr6:146023144 A/G cg23711669 chr6:146136114 FBXO30 -0.95 -11.14 -0.71 2.17e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs1372520 0.684 rs2619341 chr4:90741773 A/G cg15133208 chr4:90757351 SNCA -0.49 -5.69 -0.45 8.67e-8 Neuroticism; TGCT cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg02458000 chr6:26745757 NA 0.49 4.45 0.37 1.92e-5 Schizophrenia; TGCT cis rs13108904 0.935 rs13148614 chr4:1248357 G/C cg13395646 chr4:1353034 KIAA1530 -0.39 -5.21 -0.42 7.7300000000000005e-07 Obesity-related traits; TGCT cis rs6724607 0.905 rs7603849 chr2:191438741 A/C cg11845111 chr2:191398756 TMEM194B 0.38 5.81 0.46 5.02e-8 Pulse pressure; TGCT cis rs1552244 0.935 rs2272124 chr3:10138189 T/C cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.532 rs4401299 chr22:42156517 A/G cg03806693 chr22:41940476 POLR3H 0.91 8.69 0.62 1.82e-14 Vitiligo; TGCT cis rs9916302 0.707 rs11078903 chr17:37631924 G/A cg07936489 chr17:37558343 FBXL20 -0.61 -4.79 -0.39 4.73e-6 Glomerular filtration rate (creatinine); TGCT cis rs11779988 0.528 rs208029 chr8:17840987 A/C cg01800426 chr8:17659068 MTUS1 -0.57 -4.54 -0.38 1.32e-5 Breast cancer; TGCT cis rs13177918 0.677 rs13181401 chr5:149822596 T/C cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs35306767 0.579 rs7091502 chr10:1154979 C/T cg26597838 chr10:835615 NA 0.52 5.51 0.44 1.96e-7 Eosinophil percentage of granulocytes; TGCT cis rs4285028 0.747 rs7623901 chr3:121529011 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.95 8.29 0.6 1.55e-13 Multiple sclerosis; TGCT cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg24549020 chr5:56110836 MAP3K1 0.66 5.79 0.46 5.56e-8 Initial pursuit acceleration; TGCT cis rs7044106 0.762 rs10760115 chr9:123476952 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.35 0.5 3.69e-9 Hip circumference adjusted for BMI; TGCT cis rs2050392 0.624 rs303449 chr10:30726845 G/A cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg20007245 chr22:24372913 LOC391322 -0.73 -6.83 -0.52 3.37e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7582180 0.614 rs6737217 chr2:101006267 T/G cg14675211 chr2:100938903 LONRF2 0.49 4.7 0.39 6.74e-6 Intelligence (multi-trait analysis); TGCT cis rs9556958 0.588 rs9556964 chr13:99159306 T/C cg07423050 chr13:99094983 FARP1 -0.25 -4.8 -0.4 4.41e-6 Educational attainment (years of education); TGCT cis rs7829975 0.774 rs1039915 chr8:8679614 T/C cg06636001 chr8:8085503 FLJ10661 0.68 5.98 0.47 2.17e-8 Mood instability; TGCT cis rs11190604 1.000 rs11190613 chr10:102313997 C/T cg16342193 chr10:102329863 NA 0.39 4.95 0.41 2.37e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6665290 0.669 rs3795446 chr1:227180981 C/T cg10327440 chr1:227177885 CDC42BPA 0.88 14.4 0.79 3.14e-28 Myeloid white cell count; TGCT cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs8072100 0.837 rs8070463 chr17:45768836 A/G cg10024583 chr17:45772800 TBKBP1 0.4 4.5 0.37 1.55e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs8014204 0.836 rs8021280 chr14:75290018 C/G cg06637938 chr14:75390232 RPS6KL1 0.7 6.74 0.52 5.37e-10 Caffeine consumption; TGCT cis rs589448 0.933 rs523398 chr12:69752775 C/T cg20891283 chr12:69753455 YEATS4 0.91 10.33 0.68 1.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs10779751 0.666 rs77270747 chr1:11214584 A/C cg08854313 chr1:11322531 MTOR -0.8 -6.61 -0.51 9.98e-10 Body mass index; TGCT cis rs6750047 0.678 rs4670811 chr2:38277376 C/A cg07380506 chr2:38303506 CYP1B1 0.58 5.02 0.41 1.74e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs7662987 0.517 rs2602883 chr4:100040914 A/T cg12011299 chr4:100065546 ADH4 0.4 4.77 0.39 5.18e-6 Smoking initiation; TGCT cis rs2760061 0.784 rs1745414 chr1:228212159 T/A cg02753203 chr1:228287806 NA 0.32 6.26 0.49 5.64e-9 Diastolic blood pressure; TGCT cis rs12048904 0.533 rs1590580 chr1:101292668 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.87 7.69 0.57 3.82e-12 Multiple sclerosis; TGCT cis rs6088580 0.634 rs2424992 chr20:33012060 C/T cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs3902035 0.964 rs62424000 chr6:119014557 G/A cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs9926296 0.509 rs2159113 chr16:89832083 C/T cg26513180 chr16:89883248 FANCA 0.81 8.35 0.6 1.17e-13 Vitiligo; TGCT cis rs801193 0.569 rs2659892 chr7:66200305 A/G cg11764359 chr7:65958608 NA 0.54 4.79 0.4 4.68e-6 Aortic root size; TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs10751667 0.621 rs11246345 chr11:934924 T/C cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs514406 0.929 rs485631 chr1:53330245 A/G cg16325326 chr1:53192061 ZYG11B 0.6 6.94 0.53 1.98e-10 Monocyte count; TGCT cis rs10986311 0.752 rs3780208 chr9:127084594 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -5.23 -0.43 6.84e-7 Vitiligo; TGCT cis rs6121246 0.821 rs6119718 chr20:30331074 A/G cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs9916302 0.904 rs1619021 chr17:37739274 G/A cg07936489 chr17:37558343 FBXL20 -0.59 -4.49 -0.37 1.59e-5 Glomerular filtration rate (creatinine); TGCT cis rs2361710 0.611 rs12451471 chr17:78102517 C/T cg06718696 chr17:78121285 EIF4A3 0.57 4.56 0.38 1.22e-5 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs9611565 0.649 rs79005 chr22:41835544 G/A cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Vitiligo; TGCT cis rs72945132 0.882 rs4261311 chr11:70132902 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs317689 0.702 rs544696 chr12:69749939 T/C cg19645103 chr12:69753606 YEATS4 -0.63 -5.26 -0.43 6.09e-7 Response to diuretic therapy; TGCT trans rs9388451 0.626 rs1268074 chr6:126107791 G/C cg05039488 chr6:79577232 IRAK1BP1 -0.79 -9.1 -0.63 1.88e-15 Brugada syndrome; TGCT cis rs2243480 1.000 rs7787230 chr7:65629099 G/A cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs709400 0.526 rs8017780 chr14:103987305 C/A cg26031613 chr14:104095156 KLC1 0.72 5.77 0.46 5.85e-8 Body mass index; TGCT cis rs12911832 0.958 rs12912003 chr15:58986001 A/T cg05156742 chr15:59063176 FAM63B 0.54 5.11 0.42 1.19e-6 Schizophrenia; TGCT cis rs769267 0.930 rs4808967 chr19:19640524 A/G cg08509172 chr19:19383838 TM6SF2 -0.35 -4.54 -0.38 1.32e-5 Tonsillectomy; TGCT cis rs909674 0.865 rs5757684 chr22:39851584 G/A cg01416388 chr22:39784598 NA -0.66 -5.99 -0.47 2.09e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs854765 0.618 rs8066982 chr17:17851377 T/C cg09796270 chr17:17721594 SREBF1 0.23 4.45 0.37 1.92e-5 Total body bone mineral density; TGCT cis rs9807989 0.811 rs4485585 chr2:102970759 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs7714584 1.000 rs3906527 chr5:150266392 T/A cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs939658 0.805 rs4778924 chr15:79443363 T/C cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs4900538 0.855 rs12590993 chr14:102844064 A/G cg18135206 chr14:102964638 TECPR2 -0.2 -4.49 -0.37 1.62e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs12200560 0.505 rs4240555 chr6:97076274 T/C cg06623918 chr6:96969491 KIAA0776 0.59 5.03 0.41 1.71e-6 Coronary heart disease; TGCT cis rs9486715 0.838 rs9386576 chr6:96954717 C/T cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs422249 0.512 rs174554 chr11:61579463 A/G cg19610905 chr11:61596333 FADS2 -1.07 -12.03 -0.73 1.43e-22 Trans fatty acid levels; TGCT trans rs66573146 0.803 rs59809420 chr4:6969928 G/T cg07817883 chr1:32538562 TMEM39B 1.63 8.24 0.59 2.04e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs1403694 0.734 rs266723 chr3:186447047 A/C cg12454167 chr3:186435060 KNG1 0.44 7.05 0.53 1.09e-10 Blood protein levels; TGCT cis rs344364 0.511 rs2917519 chr16:1950479 C/A cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.11 -0.42 1.17e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs36051895 0.589 rs6476947 chr9:5204279 A/G cg02405213 chr9:5042618 JAK2 -0.74 -9.28 -0.64 7.07e-16 Pediatric autoimmune diseases; TGCT cis rs11190604 1.000 rs11190592 chr10:102291059 T/C cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs523522 0.962 rs55848094 chr12:120966659 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs11143230 1.000 rs62564005 chr9:74888383 A/T cg02514559 chr9:74675332 C9orf57 -0.22 -4.56 -0.38 1.22e-5 Suicidal ideation; TGCT cis rs6028335 0.502 rs6028235 chr20:37608550 A/G cg27552599 chr20:37590471 DHX35 0.37 4.67 0.39 7.57e-6 Alcohol and nicotine co-dependence; TGCT cis rs9393692 0.905 rs9393694 chr6:26279296 T/C cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.01e-7 Educational attainment; TGCT cis rs28386778 0.897 rs2854213 chr17:61945631 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT trans rs57221529 0.766 rs72703065 chr5:588123 C/A cg25482853 chr8:67687455 SGK3 1.2 10.12 0.67 6.42e-18 Lung disease severity in cystic fibrosis; TGCT cis rs614226 1.000 rs614226 chr12:120974510 C/T cg01236616 chr12:121019343 POP5 -1.26 -13.2 -0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT cis rs2456568 0.802 rs1574515 chr11:93629643 T/C cg16099599 chr11:93583650 C11orf90 -0.4 -5.06 -0.41 1.49e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs78487399 0.710 rs6544665 chr2:43729212 G/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.49 0.37 1.59e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4727027 0.866 rs2373438 chr7:148780287 C/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.54 5.04 0.41 1.57e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2486288 0.656 rs11639420 chr15:45559268 A/C cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.46 -0.44 2.51e-7 Glomerular filtration rate; TGCT cis rs2243480 1.000 rs1618893 chr7:66096119 C/T cg18252515 chr7:66147081 NA -1.17 -6.86 -0.52 2.91e-10 Diabetic kidney disease; TGCT cis rs561341 0.629 rs7216107 chr17:30224419 G/A cg13647721 chr17:30228624 UTP6 0.58 5.13 0.42 1.07e-6 Hip circumference adjusted for BMI; TGCT cis rs4665809 0.590 rs4665318 chr2:26424517 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.89 6.55 0.51 1.39e-9 Gut microbiome composition (summer); TGCT cis rs6582630 0.519 rs8189549 chr12:38245752 A/G cg13010199 chr12:38710504 ALG10B 0.64 5.01 0.41 1.85e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs13126513 0.510 rs10516445 chr4:100524679 C/G cg05468953 chr4:100565104 NA 0.43 6.04 0.48 1.64e-8 Metabolite levels (MHPG); TGCT cis rs9807989 0.839 rs10204837 chr2:102977730 C/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs9357506 1.000 rs12055715 chr6:46308436 A/G cg21115430 chr6:46460003 NA 0.26 5.22 0.42 7.34e-7 Body mass index; TGCT cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs3770081 1.000 rs76081054 chr2:86285037 T/G cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs7412746 0.658 rs11204739 chr1:150865760 A/G cg09365446 chr1:150670422 GOLPH3L 0.33 4.73 0.39 6.05e-6 Melanoma; TGCT cis rs7267979 1.000 rs10966 chr20:25282944 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.13 14.76 0.8 4.39e-29 Height; TGCT cis rs6582630 0.599 rs4882313 chr12:38454011 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.79 -0.4 4.57e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1971762 0.521 rs5009146 chr12:54089297 A/C cg16917193 chr12:54089295 NA 1.33 17.67 0.85 1.11e-35 Height; TGCT cis rs9467711 0.790 rs35942569 chr6:26339131 A/G cg02458000 chr6:26745757 NA -0.99 -4.44 -0.37 2e-5 Autism spectrum disorder or schizophrenia; TGCT trans rs7618501 1.000 rs6802890 chr3:49832261 A/G cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.878 rs35709953 chr2:26334997 G/A cg04944784 chr2:26401820 FAM59B 0.7 5.91 0.47 3.11e-8 Gut microbiome composition (summer); TGCT cis rs13108904 0.967 rs11247986 chr4:1294347 G/A cg13395646 chr4:1353034 KIAA1530 -0.4 -5.0 -0.41 1.93e-6 Obesity-related traits; TGCT cis rs10927875 0.662 rs698893 chr1:16302982 C/T cg22431228 chr1:16359049 CLCNKA -0.27 -5.62 -0.45 1.17e-7 Dilated cardiomyopathy; TGCT cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg13695892 chr22:41940480 POLR3H 0.9 8.66 0.61 2.17e-14 Vitiligo; TGCT cis rs734999 0.572 rs4310388 chr1:2507415 G/T cg18854424 chr1:2615690 NA 0.43 4.85 0.4 3.61e-6 Ulcerative colitis; TGCT cis rs1334894 1.000 rs72911397 chr6:35525821 A/G cg24281267 chr6:35479648 TULP1 -0.43 -4.54 -0.38 1.34e-5 Coronary artery disease; TGCT cis rs4689388 0.890 rs4688991 chr4:6302220 C/G cg25554036 chr4:6271136 WFS1 0.56 7.96 0.58 9.38e-13 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1799949 1.000 rs8176220 chr17:41222462 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.1 0.42 1.24e-6 Menopause (age at onset); TGCT cis rs501916 1.000 rs3743276 chr15:48055119 C/T cg16110827 chr15:48056943 SEMA6D 0.17 5.15 0.42 9.79e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs3820068 0.544 rs7551750 chr1:16035008 T/C cg05660106 chr1:15850417 CASP9 0.67 6.48 0.5 1.96e-9 Systolic blood pressure; TGCT cis rs1008375 1.000 rs13148861 chr4:17688338 G/A cg10189774 chr4:17578691 LAP3 -0.61 -5.18 -0.42 8.77e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs453301 0.564 rs28649568 chr8:8959671 T/G cg06636001 chr8:8085503 FLJ10661 -0.67 -5.44 -0.44 2.71e-7 Joint mobility (Beighton score); TGCT cis rs854765 0.547 rs2955384 chr17:17939573 C/T cg04398451 chr17:18023971 MYO15A -0.3 -4.85 -0.4 3.64e-6 Total body bone mineral density; TGCT cis rs1799949 1.000 rs12942277 chr17:41187974 G/C cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs62244186 0.541 rs9859879 chr3:44840166 G/A cg15687855 chr3:44754131 ZNF502 -0.53 -6.73 -0.52 5.64e-10 Depressive symptoms; TGCT cis rs514406 0.861 rs1571979 chr1:53237526 G/A cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs6733011 0.581 rs4851162 chr2:99466659 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.46 -4.51 -0.38 1.46e-5 Bipolar disorder; TGCT cis rs7945705 0.936 rs978636 chr11:8836596 C/T cg21881798 chr11:8931708 C11orf17;ST5 0.41 4.51 0.38 1.47e-5 Hemoglobin concentration; TGCT cis rs2758596 1.000 rs2758617 chr1:156160693 A/G cg24450063 chr1:156163899 SLC25A44 0.8 4.65 0.39 8.25e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs4499344 0.535 rs7260509 chr19:33121595 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.62 5.76 0.46 6.37e-8 Mean platelet volume; TGCT cis rs9522267 0.535 rs9522290 chr13:112233130 A/G cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs35306767 0.716 rs34487581 chr10:897201 G/A cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs4803468 1.000 rs10853751 chr19:41903220 G/A cg09537434 chr19:41945824 ATP5SL -0.89 -10.04 -0.67 9.93e-18 Height; TGCT cis rs593982 1.000 rs74638829 chr11:65495571 C/T cg08755490 chr11:65554678 OVOL1 -1.47 -10.68 -0.69 2.87e-19 Atopic dermatitis; TGCT cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg20887711 chr4:1340912 KIAA1530 -0.65 -5.74 -0.46 6.9e-8 Obesity-related traits; TGCT cis rs11112613 0.713 rs4015312 chr12:105948757 A/G cg03607813 chr12:105948248 NA 0.51 5.74 0.46 6.75e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs6088580 0.634 rs4142007 chr20:32990050 G/T cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.909 rs35165976 chr4:120325630 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs9291683 0.609 rs4622999 chr4:10003395 C/G cg00071950 chr4:10020882 SLC2A9 0.71 9.36 0.64 4.43e-16 Bone mineral density; TGCT trans rs6089829 0.962 rs6062776 chr20:61663736 A/G cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs910316 1.000 rs7145159 chr14:75583268 A/G cg23033748 chr14:75592666 NEK9 0.28 4.76 0.39 5.41e-6 Height; TGCT cis rs6121246 0.821 rs3181073 chr20:30307199 A/C cg18721089 chr20:30220636 NA 0.42 4.65 0.39 8.2e-6 Mean corpuscular hemoglobin; TGCT cis rs6495367 0.966 rs745029 chr15:79381779 C/T cg17916960 chr15:79447300 NA 0.37 5.28 0.43 5.56e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs7010267 0.642 rs11992136 chr8:120003727 C/G cg17171407 chr8:119960777 TNFRSF11B 0.32 6.05 0.48 1.62e-8 Total body bone mineral density (age 45-60); TGCT cis rs11924390 0.800 rs1648698 chr3:186449582 G/C cg12454167 chr3:186435060 KNG1 0.46 7.19 0.54 5.47e-11 Adiponectin levels; TGCT trans rs1005277 0.540 rs116205409 chr10:38478970 G/A cg17830980 chr10:43048298 ZNF37B -0.84 -10.46 -0.68 9.38e-19 Extrinsic epigenetic age acceleration; TGCT cis rs2177596 0.549 rs4592846 chr2:227948866 G/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.61 -0.38 9.85e-6 Body mass index; TGCT cis rs950169 0.580 rs11633762 chr15:85187152 T/C cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 2.02e-7 Schizophrenia; TGCT cis rs7666738 0.830 rs10005120 chr4:99038200 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4253772 0.515 rs6007891 chr22:46756833 C/T cg09491104 chr22:46646882 C22orf40 -0.59 -4.49 -0.37 1.59e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs4372836 0.504 rs7597048 chr2:29066756 A/G cg09522027 chr2:28974177 PPP1CB 0.5 5.16 0.42 9.51e-7 Body mass index; TGCT cis rs9296092 0.538 rs7761268 chr6:33519300 C/T cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs8078723 1.000 rs4795415 chr17:38157995 C/T cg17467752 chr17:38218738 THRA 0.55 5.34 0.43 4.24e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs9436747 0.615 rs6691346 chr1:66046397 G/A cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.03 0.41 1.69e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs2820315 1.000 rs2494114 chr1:201801011 C/G cg12730843 chr1:201915899 LMOD1 -0.27 -4.81 -0.4 4.22e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs739496 0.615 rs2285727 chr12:112093078 G/T cg10833066 chr12:111807467 FAM109A 0.36 5.06 0.41 1.46e-6 Platelet count; TGCT cis rs7572733 0.514 rs770659 chr2:198669754 G/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs2153535 0.580 rs2327058 chr6:8447018 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs8103278 1.000 rs725660 chr19:46262286 C/A cg11657440 chr19:46296263 DMWD -0.54 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs17433780 0.808 rs12125301 chr1:89508501 G/A cg09516651 chr1:89888402 LOC400759 0.26 4.94 0.41 2.48e-6 Carotid intima media thickness; TGCT cis rs9311474 0.713 rs352168 chr3:52237970 C/T cg10802521 chr3:52805072 NEK4 -0.59 -6.49 -0.5 1.88e-9 Electroencephalogram traits; TGCT cis rs801193 0.569 rs11761542 chr7:66218196 G/A cg11764359 chr7:65958608 NA 0.54 4.79 0.4 4.68e-6 Aortic root size; TGCT cis rs13188771 0.527 rs408727 chr5:100877888 T/C cg10455971 chr5:101119566 NA 0.44 4.44 0.37 1.95e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs921968 0.612 rs10189479 chr2:219287276 C/A cg02176678 chr2:219576539 TTLL4 -0.43 -6.33 -0.49 4.18e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs3806843 0.545 rs251375 chr5:140252960 T/G cg09824255 chr5:140014002 CD14 -0.26 -4.54 -0.38 1.3e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs13191362 1.000 rs35911566 chr6:162994154 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.32 0.43 4.73e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3096299 0.658 rs4291902 chr16:89560315 G/C cg06640241 chr16:89574553 SPG7 0.83 9.52 0.65 1.81e-16 Multiple myeloma (IgH translocation); TGCT cis rs916888 0.773 rs169201 chr17:44790203 A/G cg01570182 chr17:44337453 NA 1.08 9.48 0.65 2.25e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1670533 1.000 rs34956924 chr4:1047270 T/C cg27284194 chr4:1044797 NA 0.68 5.75 0.46 6.41e-8 Recombination rate (females); TGCT cis rs7586879 0.828 rs11675013 chr2:25107208 G/A cg01884057 chr2:25150051 NA 0.26 4.67 0.39 7.85e-6 Body mass index; TGCT cis rs10504229 0.593 rs76118562 chr8:57988110 G/C cg02725872 chr8:58115012 NA -0.41 -4.94 -0.41 2.47e-6 Developmental language disorder (linguistic errors); TGCT cis rs3741404 1.000 rs11603042 chr11:64003843 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.87 9.44 0.65 2.9e-16 Platelet count; TGCT cis rs9486719 1.000 rs11153018 chr6:96956137 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7312933 0.584 rs7974654 chr12:42630466 C/A cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.16 0.42 9.61e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1061377 1.000 rs28465556 chr4:39121189 T/G cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs7552404 1.000 rs6672180 chr1:76123973 C/G cg10523679 chr1:76189770 ACADM 0.93 10.32 0.68 2.12e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2456568 0.741 rs2102332 chr11:93635281 G/T cg17595323 chr11:93583763 C11orf90 -0.47 -6.44 -0.5 2.38e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2440129 0.611 rs10852889 chr17:6900845 C/T cg21237687 chr17:6899380 ALOX12 0.53 5.91 0.47 3.05e-8 Tonsillectomy; TGCT cis rs17162190 0.569 rs3122646 chr1:26829071 A/G cg02450742 chr1:26856648 RPS6KA1 -0.54 -4.46 -0.37 1.79e-5 Mean corpuscular volume; TGCT cis rs4389656 0.857 rs5001282 chr5:6757668 T/C cg10857441 chr5:6722123 POLS -0.21 -4.6 -0.38 1.03e-5 Coronary artery disease; TGCT cis rs7223966 1.000 rs8075061 chr17:61804723 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1670533 1.000 rs11725984 chr4:1087338 C/T cg20887711 chr4:1340912 KIAA1530 0.66 5.33 0.43 4.49e-7 Recombination rate (females); TGCT cis rs9633740 0.773 rs7080009 chr10:82269461 T/C cg01528321 chr10:82214614 TSPAN14 1.03 8.28 0.6 1.66e-13 Post bronchodilator FEV1; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg23131131 chr22:24373011 LOC391322 -0.58 -5.66 -0.45 1e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3761847 0.593 rs10985140 chr9:123822837 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 4.52 0.38 1.42e-5 Rheumatoid arthritis; TGCT cis rs10782582 0.593 rs115291524 chr1:76141811 A/G cg22875332 chr1:76189707 ACADM -0.54 -6.17 -0.48 8.76e-9 Daytime sleep phenotypes; TGCT cis rs477895 0.653 rs34089806 chr11:63887987 C/T cg23719950 chr11:63933701 MACROD1 -0.71 -5.93 -0.47 2.77e-8 Mean platelet volume; TGCT cis rs344364 0.511 rs1742464 chr16:1947335 A/G cg09830162 chr16:1889614 FAHD1;C16orf73 0.45 5.08 0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg26516362 chr5:178986906 RUFY1 -0.43 -4.71 -0.39 6.55e-6 Lung cancer; TGCT cis rs3820068 0.603 rs16851884 chr1:15961871 A/G cg05660106 chr1:15850417 CASP9 0.83 8.19 0.59 2.78e-13 Systolic blood pressure; TGCT cis rs9517320 0.534 rs4772088 chr13:99138270 T/G cg07423050 chr13:99094983 FARP1 -0.29 -5.62 -0.45 1.17e-7 Longevity; TGCT cis rs4746818 0.818 rs10823302 chr10:70895418 G/T cg11621586 chr10:70884670 VPS26A 1.21 10.66 0.69 3.17e-19 Left atrial antero-posterior diameter; TGCT cis rs7949030 0.622 rs34894392 chr11:62374821 A/G cg22862634 chr11:62369728 EML3;MTA2 0.69 8.75 0.62 1.27e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7017914 0.840 rs1481804 chr8:71969430 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.63 -5.74 -0.46 6.9e-8 Bone mineral density; TGCT cis rs7432375 0.966 rs7618871 chr3:136400420 G/T cg12473912 chr3:136751656 NA -0.34 -4.93 -0.41 2.55e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs12580194 0.593 rs61957933 chr12:55744710 T/G cg10672482 chr12:55725839 OR6C3 -0.52 -4.66 -0.39 8.13e-6 Cancer; TGCT cis rs11252926 0.537 rs6560836 chr10:444997 C/T cg20256804 chr10:444983 DIP2C -0.22 -4.61 -0.38 1.01e-5 Psychosis in Alzheimer's disease; TGCT cis rs7772486 0.686 rs2142983 chr6:146069701 G/C cg05347473 chr6:146136440 FBXO30 -0.49 -4.52 -0.38 1.42e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1218582 0.741 rs4339857 chr1:154888962 A/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs9467711 0.606 rs9366653 chr6:26354247 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg19318889 chr4:1322082 MAEA 0.19 4.94 0.41 2.42e-6 Longevity; TGCT cis rs1371867 0.846 rs924057 chr8:101266157 A/G cg06636551 chr8:101224915 SPAG1 0.43 5.95 0.47 2.58e-8 Atrioventricular conduction; TGCT cis rs16866061 1.000 rs4674916 chr2:225365635 C/A cg12698349 chr2:225449008 CUL3 1.0 10.02 0.67 1.14e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs2762353 0.779 rs3799352 chr6:25822620 C/T cg12310025 chr6:25882481 NA -0.59 -6.04 -0.48 1.65e-8 Blood metabolite levels; TGCT cis rs4851254 0.660 rs77023845 chr2:100712346 G/A cg07810366 chr2:100720526 AFF3 -0.45 -4.72 -0.39 6.35e-6 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.845 rs72823935 chr17:28008595 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.76e-11 Coffee consumption (cups per day); TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg27535305 chr1:53392650 SCP2 -0.28 -5.61 -0.45 1.28e-7 Monocyte count; TGCT cis rs17253792 0.818 rs78393484 chr14:56065802 T/C cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs4455778 0.580 rs10229899 chr7:49110363 C/T cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs35160687 0.871 rs11127028 chr2:86537509 A/T cg04877910 chr2:85804641 VAMP8 0.34 4.51 0.38 1.49e-5 Night sleep phenotypes; TGCT cis rs9790314 0.905 rs6441370 chr3:160993754 C/T cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT trans rs3822625 0.541 rs112793966 chr5:56204118 C/T cg25190722 chr1:3801660 DFFB 0.56 6.67 0.51 7.53e-10 Breast cancer (early onset); TGCT cis rs2115630 1.000 rs2115630 chr15:85364516 C/T cg17173187 chr15:85201210 NMB -0.4 -4.84 -0.4 3.82e-6 P wave terminal force; TGCT cis rs9611565 0.694 rs2142505 chr22:41820541 A/G cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs8102476 0.905 rs7250689 chr19:38753625 C/T cg14131526 chr19:38747285 PPP1R14A 0.53 4.63 0.38 8.93e-6 Prostate cancer;Prostate cancer (SNP x SNP interaction); TGCT cis rs10507380 0.824 rs77605840 chr13:27921658 G/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs6964587 0.869 rs2374519 chr7:91541481 T/C cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs2235649 0.552 rs7203361 chr16:1963085 G/A cg02432467 chr16:1963432 HS3ST6 -0.31 -4.63 -0.38 9.07e-6 Blood metabolite levels; TGCT cis rs7959452 0.718 rs10878963 chr12:69717166 T/G cg11871910 chr12:69753446 YEATS4 0.59 5.83 0.46 4.59e-8 Blood protein levels; TGCT trans rs1814175 0.817 rs10769617 chr11:49810421 G/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs1865760 0.865 rs10946800 chr6:25957773 C/T cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs8141529 0.509 rs12628211 chr22:29239250 T/C cg02153584 chr22:29168773 CCDC117 0.62 5.05 0.41 1.57e-6 Lymphocyte counts; TGCT cis rs10193935 1.000 rs57883795 chr2:42387926 C/T cg27598129 chr2:42591480 NA -0.4 -5.05 -0.41 1.52e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6545883 0.965 rs7591345 chr2:61729641 T/A cg15711740 chr2:61764176 XPO1 -0.55 -5.01 -0.41 1.85e-6 Tuberculosis; TGCT cis rs17376456 1.000 rs9968749 chr5:93509559 A/G cg21475434 chr5:93447410 FAM172A 0.62 4.5 0.37 1.54e-5 Diabetic retinopathy; TGCT cis rs12142240 0.659 rs1984491 chr1:46858607 T/G cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs7824557 0.620 rs6996368 chr8:11182704 G/A cg21775007 chr8:11205619 TDH 0.63 6.14 0.48 1.02e-8 Retinal vascular caliber; TGCT cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs6964587 0.810 rs408 chr7:91556284 A/G cg17063962 chr7:91808500 NA -0.89 -9.52 -0.65 1.81e-16 Breast cancer; TGCT cis rs483180 0.512 rs1163251 chr1:120209755 T/C cg19096424 chr1:120255104 PHGDH -0.57 -5.45 -0.44 2.62e-7 Macular telangiectasia type 2; TGCT cis rs13256369 0.826 rs7846050 chr8:8575669 A/G cg18904891 chr8:8559673 CLDN23 0.6 5.49 0.44 2.19e-7 Obesity-related traits; TGCT cis rs78487399 0.908 rs77888770 chr2:43787107 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.67 4.52 0.38 1.41e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9325144 0.534 rs6582538 chr12:38629997 A/C cg26384229 chr12:38710491 ALG10B -0.65 -6.03 -0.48 1.74e-8 Morning vs. evening chronotype; TGCT cis rs2657888 0.628 rs2638334 chr12:56882528 A/C cg23002907 chr12:56915593 RBMS2 0.4 5.26 0.43 6.06e-7 Adiponectin levels; TGCT cis rs10504229 0.953 rs72652908 chr8:58191324 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7829975 0.606 rs7837026 chr8:8801692 T/C cg06636001 chr8:8085503 FLJ10661 -0.83 -7.29 -0.55 3.26e-11 Mood instability; TGCT cis rs6495122 0.532 rs2472304 chr15:75044238 G/A cg13906792 chr15:75199810 C15orf17 -0.22 -4.71 -0.39 6.64e-6 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs9611565 0.512 rs2050031 chr22:42152266 A/G cg06634786 chr22:41940651 POLR3H 0.86 8.01 0.58 7.16e-13 Vitiligo; TGCT cis rs2797160 1.000 rs1832979 chr6:125997436 A/G cg05901451 chr6:126070800 HEY2 -0.73 -6.5 -0.5 1.73e-9 Endometrial cancer; TGCT cis rs9494142 0.592 rs1547247 chr6:135390836 C/T cg24558204 chr6:135376177 HBS1L 0.49 4.69 0.39 7.05e-6 Lymphocyte counts;Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs736801 0.538 rs2548998 chr5:131832514 G/A cg00255919 chr5:131827918 IRF1 -0.2 -4.5 -0.37 1.57e-5 Breast cancer;Mosquito bite size; TGCT cis rs2439831 0.850 rs28696802 chr15:44140395 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs4665809 0.627 rs13014338 chr2:26463024 C/T cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs4319547 0.956 rs10744275 chr12:123048618 A/G cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.5 -0.44 2.05e-7 Body mass index; TGCT cis rs9393692 0.905 rs34916901 chr6:26286149 G/T cg05868516 chr6:26286170 HIST1H4H 0.63 5.9 0.47 3.18e-8 Educational attainment; TGCT cis rs523522 0.962 rs10774549 chr12:120891172 C/T cg12219531 chr12:120966889 COQ5 0.79 6.99 0.53 1.47e-10 High light scatter reticulocyte count; TGCT cis rs10875595 0.779 rs1363451 chr5:140658138 G/A cg24830062 chr5:140700576 TAF7 -0.6 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs1801251 1.000 rs67013068 chr2:233608253 G/C cg08000102 chr2:233561755 GIGYF2 0.63 6.49 0.5 1.88e-9 Coronary artery disease; TGCT cis rs6700896 0.522 rs4655583 chr1:66155407 C/A cg14976592 chr1:65886160 LEPROT;LEPR 0.63 4.84 0.4 3.78e-6 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7255045 0.788 rs2290688 chr19:12958697 T/C cg23899408 chr19:12877188 HOOK2 -0.63 -5.3 -0.43 5.11e-7 Mean corpuscular volume; TGCT cis rs9399135 0.527 rs61738492 chr6:135282771 G/A cg24558204 chr6:135376177 HBS1L 0.46 4.67 0.39 7.71e-6 Red blood cell count; TGCT cis rs921968 0.541 rs1863704 chr2:219562675 C/T cg02176678 chr2:219576539 TTLL4 -0.5 -7.05 -0.54 1.09e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs941408 0.515 rs1736193 chr19:2785273 G/C cg17333051 chr19:2783644 SGTA 0.42 5.11 0.42 1.2e-6 Total cholesterol levels; TGCT cis rs453301 0.606 rs6601279 chr8:8908231 G/A cg06636001 chr8:8085503 FLJ10661 -0.71 -5.8 -0.46 5.19e-8 Joint mobility (Beighton score); TGCT cis rs5769765 0.728 rs6520064 chr22:50294469 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -12.1 -0.74 9.56e-23 Schizophrenia; TGCT cis rs9467773 0.620 rs9467810 chr6:26608261 A/C cg11502198 chr6:26597334 ABT1 0.54 4.95 0.41 2.41e-6 Intelligence (multi-trait analysis); TGCT cis rs2191566 0.845 rs7258517 chr19:44535999 G/T cg03039196 chr19:44506973 ZNF230 0.56 4.76 0.39 5.38e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs10504229 1.000 rs116995796 chr8:58181960 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs611744 0.781 rs656406 chr8:109173843 G/A cg21045802 chr8:109455806 TTC35 0.69 6.06 0.48 1.51e-8 Dupuytren's disease; TGCT cis rs1348850 0.789 rs2197611 chr2:178369036 G/C cg22681709 chr2:178499509 PDE11A -0.35 -4.55 -0.38 1.27e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs896854 0.902 rs726816 chr8:95968413 T/G cg13393036 chr8:95962371 TP53INP1 -0.63 -8.6 -0.61 2.94e-14 Type 2 diabetes; TGCT cis rs10504229 0.593 rs78459635 chr8:58004995 G/T cg11062466 chr8:58055876 NA 0.43 4.52 0.38 1.45e-5 Developmental language disorder (linguistic errors); TGCT cis rs8180040 1.000 rs295442 chr3:47335881 A/C cg27129171 chr3:47204927 SETD2 0.72 8.98 0.63 3.59e-15 Colorectal cancer; TGCT cis rs694739 0.930 rs574087 chr11:64102948 A/G cg02228329 chr11:64053129 BAD;GPR137 0.78 7.83 0.58 1.86e-12 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs425277 0.606 rs262664 chr1:2083537 G/C cg03732007 chr1:2071316 PRKCZ 0.28 6.63 0.51 9.05e-10 Height; TGCT cis rs875971 0.638 rs801216 chr7:66011667 T/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs12188164 0.965 rs11744539 chr5:451425 C/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs707040 0.921 rs2037662 chr2:155231121 T/C cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs6964587 1.000 rs733957 chr7:91707197 C/T cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs6840360 0.642 rs7682770 chr4:152390413 A/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs664172 1 rs664172 chr15:78862762 G/A cg24631222 chr15:78858424 CHRNA5 0.86 6.45 0.5 2.3e-9 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9372498 0.536 rs7356947 chr6:118767920 A/G cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs6952808 0.692 rs12666575 chr7:2004421 C/T cg04267008 chr7:1944627 MAD1L1 -0.36 -4.68 -0.39 7.34e-6 Bipolar disorder and schizophrenia; TGCT cis rs2014572 0.967 rs11667407 chr19:57763122 C/T cg24459738 chr19:57751996 ZNF805 -0.58 -5.7 -0.46 8.38e-8 Hyperactive-impulsive symptoms; TGCT cis rs67311347 0.869 rs9832311 chr3:40381322 A/T cg17264618 chr3:40429014 ENTPD3 0.32 4.63 0.38 9.1e-6 Renal cell carcinoma; TGCT trans rs3780486 1.000 rs10813957 chr9:33153527 G/T cg04842962 chr6:43655489 MRPS18A 1.27 11.2 0.71 1.52e-20 IgG glycosylation; TGCT cis rs909674 0.818 rs5750833 chr22:39843091 C/A cg11247378 chr22:39784982 NA -0.71 -8.48 -0.61 5.76e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7666738 0.830 rs36047842 chr4:99004902 C/A cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs1552244 0.882 rs2030564 chr3:10039044 A/G cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.3e-6 Alzheimer's disease; TGCT cis rs739401 0.527 rs423236 chr11:3065916 C/T cg05729581 chr11:3078854 CARS -0.57 -5.27 -0.43 5.81e-7 Longevity; TGCT cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg26119090 chr2:26468346 HADHA;HADHB -0.89 -6.4 -0.5 2.85e-9 Gut microbiome composition (summer); TGCT cis rs28595532 0.920 rs116739193 chr4:119771024 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs523522 0.962 rs4767904 chr12:120930798 T/G cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs7822232 0.908 rs56138570 chr8:145142206 G/A cg26272248 chr8:145163034 KIAA1875 -0.49 -4.81 -0.4 4.24e-6 Blood metabolite levels; TGCT cis rs7811142 0.945 rs6974282 chr7:100098295 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 7.77 0.57 2.61e-12 Platelet count; TGCT cis rs6500602 0.855 rs2304631 chr16:4475868 A/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.43 5.29 0.43 5.42e-7 Schizophrenia; TGCT cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg03806693 chr22:41940476 POLR3H 1.15 13.16 0.76 2.69e-25 Vitiligo; TGCT cis rs1395 1.000 rs6717980 chr2:27452784 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.68 0.51 7.27e-10 Blood metabolite levels; TGCT cis rs4363385 0.507 rs6587710 chr1:152870716 A/G cg07796016 chr1:152779584 LCE1C -0.45 -5.09 -0.42 1.32e-6 Inflammatory skin disease; TGCT cis rs10927875 0.541 rs761759 chr1:16342350 A/T cg21385522 chr1:16154831 NA 0.46 4.85 0.4 3.64e-6 Dilated cardiomyopathy; TGCT trans rs9388451 0.626 rs2875881 chr6:126072853 C/G cg05039488 chr6:79577232 IRAK1BP1 -0.87 -9.71 -0.66 6.39e-17 Brugada syndrome; TGCT cis rs9943465 0.539 rs34862546 chr10:131990793 C/G cg00179795 chr10:131695114 EBF3 -0.35 -4.45 -0.37 1.87e-5 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs7809950 0.861 rs10264412 chr7:107183877 G/A cg23024343 chr7:107201750 COG5 -0.48 -6.95 -0.53 1.82e-10 Coronary artery disease; TGCT trans rs797680 0.856 rs10874759 chr1:93630172 G/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.78 -0.52 4.33e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs66573146 1.000 rs59683609 chr4:6964910 C/G cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs8177253 0.761 rs35332919 chr3:133519002 T/A cg20276088 chr3:133502917 NA -0.28 -5.88 -0.47 3.56e-8 Iron status biomarkers; TGCT cis rs1997103 0.822 rs10273426 chr7:55417857 G/A cg17469321 chr7:55412551 NA 0.61 5.91 0.47 3.03e-8 QRS interval (sulfonylurea treatment interaction); TGCT cis rs903263 0.965 rs6689844 chr1:84592019 G/A cg09664975 chr1:84543551 PRKACB 0.49 4.55 0.38 1.27e-5 Breast cancer (male); TGCT cis rs651907 0.535 rs1460097 chr3:101497569 C/T cg12386194 chr3:101231763 SENP7 0.47 4.7 0.39 6.87e-6 Colorectal cancer; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg07167872 chr1:205819463 PM20D1 0.6 7.82 0.57 2.02e-12 Menarche (age at onset); TGCT cis rs6987853 0.966 rs2084709 chr8:42423190 A/G cg20539142 chr8:42623718 CHRNA6 -0.21 -5.11 -0.42 1.21e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs250677 0.652 rs250675 chr5:148438565 A/C cg18129178 chr5:148520854 ABLIM3 0.42 5.46 0.44 2.51e-7 Breast cancer; TGCT cis rs9902453 0.904 rs7219456 chr17:28374112 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs597539 0.652 rs686390 chr11:68656077 T/C cg21862992 chr11:68658383 NA 0.46 6.38 0.5 3.26e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4808199 0.895 rs6511036 chr19:19582651 A/G cg03709012 chr19:19516395 GATAD2A 1.0 7.8 0.57 2.23e-12 Nonalcoholic fatty liver disease; TGCT cis rs4689388 0.926 rs4234730 chr4:6296343 A/G cg25554036 chr4:6271136 WFS1 0.54 7.32 0.55 2.66e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7582180 0.629 rs11682557 chr2:100948008 C/A cg08017756 chr2:100939284 LONRF2 -0.29 -4.62 -0.38 9.47e-6 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.694 rs2155752 chr11:130755998 C/T cg14779329 chr11:130786720 SNX19 0.29 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs308403 0.640 rs34518478 chr4:123719999 T/G cg10495464 chr4:123653540 BBS12;LOC729338 0.66 5.7 0.46 8.18e-8 Blood protein levels; TGCT cis rs1215050 0.791 rs2865943 chr4:98778449 C/T cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg21226059 chr5:178986404 RUFY1 -0.55 -6.37 -0.5 3.4e-9 Lung cancer; TGCT cis rs9527 0.615 rs7073295 chr10:104672233 A/G cg15744005 chr10:104629667 AS3MT -0.45 -5.31 -0.43 4.9e-7 Arsenic metabolism; TGCT cis rs11098499 0.955 rs1511015 chr4:120170473 A/C cg24670566 chr4:120433619 PDE5A 0.23 4.58 0.38 1.13e-5 Corneal astigmatism; TGCT cis rs12142240 0.698 rs17361936 chr1:46862893 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs8013055 0.846 rs8003942 chr14:105971670 A/G cg23356831 chr14:105996513 TMEM121 0.41 6.33 0.49 4.01e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs12134133 1.000 rs2782854 chr1:207462714 A/G cg02152968 chr1:207494213 CD55 0.57 4.47 0.37 1.74e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs7647973 0.667 rs9869256 chr3:49624095 T/G cg03060546 chr3:49711283 APEH 0.62 4.83 0.4 4e-6 Menarche (age at onset); TGCT cis rs138249 0.867 rs138226 chr22:50556787 A/G cg24864161 chr22:50528282 MOV10L1 0.47 5.02 0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs11190604 0.697 rs10748795 chr10:102194818 A/T cg23241863 chr10:102295624 HIF1AN -0.66 -4.9 -0.4 2.98e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs72615157 0.634 rs11762932 chr7:99792666 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 -0.67 -5.33 -0.43 4.45e-7 Lung function (FEV1/FVC); TGCT cis rs1005277 0.579 rs2505237 chr10:38438898 T/G cg13531842 chr10:38383804 ZNF37A -0.39 -4.64 -0.38 8.78e-6 Extrinsic epigenetic age acceleration; TGCT cis rs854765 1.000 rs854765 chr17:18012730 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.67 -6.45 -0.5 2.27e-9 Total body bone mineral density; TGCT cis rs2742417 1.000 rs2742422 chr3:45732820 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs875971 1.000 rs7781698 chr7:65896312 A/T cg00343986 chr7:65444356 GUSB 0.2 4.5 0.37 1.57e-5 Aortic root size; TGCT cis rs2692947 0.631 rs2312954 chr2:96772447 C/T cg05933789 chr2:97190408 NA -0.16 -4.74 -0.39 5.75e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7267979 1.000 rs1888997 chr20:25298988 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs6762477 0.748 rs11711407 chr3:50225029 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.75 -7.79 -0.57 2.37e-12 Menarche (age at onset); TGCT cis rs2354432 0.607 rs9661159 chr1:146757923 G/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg10263370 chr3:44754102 ZNF502 -0.45 -5.47 -0.44 2.36e-7 Depressive symptoms; TGCT cis rs10875746 0.855 rs10875729 chr12:48426726 A/G cg20731937 chr12:48336164 NA 0.67 5.15 0.42 9.92e-7 Longevity (90 years and older); TGCT cis rs7119 0.717 rs11630916 chr15:77821331 G/A cg27398640 chr15:77910606 LINGO1 -0.25 -4.61 -0.38 9.7e-6 Type 2 diabetes; TGCT cis rs4690686 0.500 rs7657249 chr4:177275198 A/G cg17059388 chr4:177262070 NA 0.29 4.59 0.38 1.09e-5 Essential tremor; TGCT cis rs10504229 1.000 rs56350499 chr8:58178139 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7513165 0.935 rs7538038 chr1:204161026 C/T cg04791601 chr1:204159016 NA -0.27 -5.25 -0.43 6.42e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs2153535 0.580 rs9406159 chr6:8464859 C/G cg07606381 chr6:8435919 SLC35B3 0.55 5.16 0.42 9.35e-7 Motion sickness; TGCT cis rs295140 0.605 rs159320 chr2:201187775 A/G cg23649088 chr2:200775458 C2orf69 0.28 4.55 0.38 1.25e-5 QT interval; TGCT cis rs68170813 0.652 rs117775624 chr7:107124113 C/T cg02696742 chr7:106810147 HBP1 -0.65 -4.93 -0.4 2.55e-6 Coronary artery disease; TGCT cis rs2046867 0.818 rs9814945 chr3:72803590 C/T cg25664220 chr3:72788482 NA -0.54 -6.8 -0.52 3.92e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs3125734 0.633 rs3765002 chr10:64006124 G/T cg09941381 chr10:64027924 RTKN2 -0.37 -5.58 -0.45 1.46e-7 Rheumatoid arthritis; TGCT cis rs910316 1.000 rs7303 chr14:75520065 T/C cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT trans rs916888 0.821 rs199505 chr17:44859410 A/G cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9527 0.544 rs11191549 chr10:104846797 C/T cg04362960 chr10:104952993 NT5C2 0.67 5.76 0.46 6.28e-8 Arsenic metabolism; TGCT cis rs854765 0.647 rs1008136 chr17:18027142 C/G cg04398451 chr17:18023971 MYO15A -0.39 -6.7 -0.52 6.51e-10 Total body bone mineral density; TGCT cis rs12220238 1.000 rs11000894 chr10:75906598 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs34638657 0.732 rs12595971 chr16:82200309 T/C cg09439754 chr16:82129088 HSD17B2 -0.24 -4.63 -0.38 9.27e-6 Lung adenocarcinoma; TGCT cis rs7666738 0.830 rs7673880 chr4:99057262 A/G cg18180107 chr4:99064573 C4orf37 0.54 4.86 0.4 3.54e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs61990749 0.597 rs12896026 chr14:78244436 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.64 4.5 0.37 1.54e-5 Fibroblast growth factor basic levels; TGCT cis rs6563842 0.563 rs9603786 chr13:41316364 G/A cg21288729 chr13:41239152 FOXO1 0.95 9.36 0.64 4.52e-16 Eosinophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs6933660 0.720 rs6936936 chr6:151753395 A/G cg17179660 chr6:151773299 C6orf211;RMND1 -0.53 -4.81 -0.4 4.28e-6 Menarche (age at onset); TGCT cis rs9467773 1.000 rs6910899 chr6:26524339 A/G cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.727 rs5745433 chr1:76333163 T/G cg03433033 chr1:76189801 ACADM 0.59 5.95 0.47 2.53e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10501293 0.746 rs4578378 chr11:43031293 C/T cg03447554 chr11:43094025 NA 0.44 6.29 0.49 5.05e-9 Cognitive performance; TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg10150615 chr22:24372951 LOC391322 0.86 7.67 0.57 4.36e-12 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs910316 1.000 rs10143132 chr14:75525850 G/A cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs2658782 0.547 rs3020052 chr11:93055184 C/G cg15737290 chr11:93063684 CCDC67 1.06 11.42 0.72 4.37e-21 Pulmonary function decline; TGCT cis rs4862750 0.914 rs7658351 chr4:187875680 G/T cg10295955 chr4:187884368 NA -0.97 -14.61 -0.8 1e-28 Lobe attachment (rater-scored or self-reported); TGCT cis rs950027 0.596 rs2467865 chr15:45638307 T/C cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs1371867 0.875 rs1962901 chr8:101326428 A/G cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs12765878 0.580 rs11191833 chr10:105619678 G/A cg11005552 chr10:105648138 OBFC1 -0.39 -6.06 -0.48 1.54e-8 Coronary artery disease; TGCT cis rs12477438 0.798 rs1993230 chr2:99686079 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs55883249 1.000 rs17362902 chr2:9768564 C/T cg23886495 chr2:9695866 ADAM17 -0.74 -4.53 -0.38 1.37e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9467773 0.620 rs9461276 chr6:26595168 T/C cg26531700 chr6:26746687 NA 0.5 4.65 0.39 8.29e-6 Intelligence (multi-trait analysis); TGCT cis rs7937682 0.847 rs583032 chr11:111432757 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.25 -0.68 3.19e-18 Primary sclerosing cholangitis; TGCT cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs9916302 0.904 rs10852933 chr17:37698194 G/T cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs4595586 0.870 rs2388172 chr12:39290539 A/G cg10518543 chr12:38710700 ALG10B 0.47 4.6 0.38 1.01e-5 Morning vs. evening chronotype; TGCT cis rs1580019 0.587 rs9638880 chr7:32552401 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.94 0.41 2.43e-6 Cognitive ability; TGCT cis rs6867032 0.958 rs9312970 chr5:2002415 C/A cg26168224 chr5:2018326 NA -0.39 -6.05 -0.48 1.56e-8 Gut microbiome composition (winter); TGCT cis rs2404602 0.569 rs283793 chr15:76774752 G/A cg22467129 chr15:76604101 ETFA -0.46 -4.71 -0.39 6.53e-6 Blood metabolite levels; TGCT cis rs9814567 0.929 rs2241556 chr3:134183312 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.97 9.51 0.65 1.89e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs10426930 0.607 rs877287 chr19:5041989 G/A cg09001777 chr19:5851504 FUT3 0.2 4.57 0.38 1.14e-5 Monocyte percentage of white cells; TGCT cis rs9733 0.596 rs72702523 chr1:150650425 G/T cg04414720 chr1:150670196 GOLPH3L 0.39 5.11 0.42 1.19e-6 Tonsillectomy; TGCT cis rs7772486 0.686 rs9497380 chr6:145955305 T/C cg23711669 chr6:146136114 FBXO30 0.84 9.17 0.64 1.25e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2835872 0.932 rs73222345 chr21:39036569 G/A cg20424643 chr21:39039972 KCNJ6 0.25 5.41 0.44 3.16e-7 Electroencephalographic traits in alcoholism; TGCT cis rs3099143 1.000 rs4886832 chr15:77121196 G/A cg21673338 chr15:77095150 SCAPER 0.51 4.88 0.4 3.17e-6 Recalcitrant atopic dermatitis; TGCT cis rs1887596 0.639 rs11149445 chr13:27162727 A/G cg01312412 chr13:27282625 NA 0.32 5.72 0.46 7.42e-8 Facial morphology (factor 3, length of philtrum); TGCT cis rs597539 0.652 rs686877 chr11:68637169 G/A cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs896854 0.654 rs4735339 chr8:95974373 C/T cg13393036 chr8:95962371 TP53INP1 -0.63 -8.52 -0.61 4.43e-14 Type 2 diabetes; TGCT cis rs727505 1.000 rs722560 chr7:124488035 T/C cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs2073300 1.000 rs6137982 chr20:23468892 T/A cg09953122 chr20:23471693 CST8 -0.68 -4.7 -0.39 6.92e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7666738 0.546 rs10007424 chr4:98885450 C/T cg17366294 chr4:99064904 C4orf37 0.67 6.0 0.47 2e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6598955 0.670 rs6676619 chr1:26539035 T/G cg04990556 chr1:26633338 UBXN11 -0.89 -11.24 -0.71 1.2e-20 Obesity-related traits; TGCT cis rs7666738 0.830 rs1025203 chr4:99023073 G/A cg18180107 chr4:99064573 C4orf37 0.54 4.8 0.4 4.53e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 0.631 rs9646213 chr15:76807672 G/C cg22467129 chr15:76604101 ETFA -0.56 -6.57 -0.51 1.28e-9 Blood metabolite levels; TGCT cis rs13191362 1.000 rs13191362 chr6:163033350 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.8 6.91 0.53 2.2e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7226408 0.857 rs11081970 chr18:34484766 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs910316 0.763 rs175450 chr14:75590340 G/A cg08847533 chr14:75593920 NEK9 -0.85 -8.58 -0.61 3.22e-14 Height; TGCT cis rs523522 0.962 rs4767902 chr12:120910004 C/T cg12219531 chr12:120966889 COQ5 0.83 7.33 0.55 2.6e-11 High light scatter reticulocyte count; TGCT cis rs9393777 0.528 rs35982103 chr6:27243134 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -5.17 -0.42 9.21e-7 Intelligence (multi-trait analysis); TGCT cis rs854765 0.583 rs8078105 chr17:17853782 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs28595532 0.920 rs55649377 chr4:119752745 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs28595532 0.841 rs115725150 chr4:119768647 T/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs7267979 1.000 rs6050590 chr20:25384994 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4242434 0.927 rs2272718 chr8:22457388 G/A cg03733263 chr8:22462867 KIAA1967 1.16 19.41 0.87 2.12e-39 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs644148 0.803 rs2686771 chr19:44999494 T/C cg15540054 chr19:45004280 ZNF180 -0.65 -5.33 -0.43 4.48e-7 Personality dimensions; TGCT cis rs7264396 0.790 rs2295355 chr20:34252654 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs2836633 0.929 rs2836602 chr21:40039169 A/T cg12884169 chr21:40033163 ERG -0.44 -4.8 -0.4 4.56e-6 Coronary artery disease; TGCT cis rs4642101 1.000 rs7650482 chr3:12841804 A/G cg05775895 chr3:12838266 CAND2 0.54 5.16 0.42 9.56e-7 QRS complex (12-leadsum); TGCT cis rs1538970 0.962 rs2153608 chr1:45813941 C/T cg05343316 chr1:45956843 TESK2 -0.67 -5.07 -0.41 1.39e-6 Platelet count; TGCT cis rs9796 0.700 rs2305656 chr15:41279519 T/A cg18705301 chr15:41695430 NDUFAF1 -0.51 -6.46 -0.5 2.16e-9 Menopause (age at onset); TGCT cis rs263156 0.967 rs263105 chr6:142876920 T/A cg18419694 chr6:143832440 FUCA2 -0.38 -4.53 -0.38 1.36e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs9916302 0.904 rs7221875 chr17:37543328 G/A cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs7618915 0.547 rs34610878 chr3:52759169 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs7524258 0.934 rs6689453 chr1:7288384 C/T cg07173049 chr1:7289937 CAMTA1 0.27 4.44 0.37 1.97e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs7666738 0.830 rs7657982 chr4:99044015 G/A cg17366294 chr4:99064904 C4orf37 0.72 7.4 0.55 1.76e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9296092 0.500 rs9469503 chr6:33527234 G/T cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6690583 0.623 rs12037219 chr1:85505951 G/A cg20280350 chr1:85513789 MCOLN3 -0.71 -4.53 -0.38 1.38e-5 Serum sulfate level; TGCT cis rs4074961 0.669 rs6687545 chr1:38071195 C/T cg17933807 chr1:38061675 GNL2 0.96 11.42 0.72 4.35e-21 Axial length; TGCT cis rs2228479 0.614 rs1137042 chr16:89975638 A/G cg06558623 chr16:89946397 TCF25 0.38 4.58 0.38 1.12e-5 Skin colour saturation; TGCT cis rs8180040 0.903 rs6791842 chr3:47279810 T/C cg27129171 chr3:47204927 SETD2 0.7 8.64 0.61 2.35e-14 Colorectal cancer; TGCT cis rs6964587 1.000 rs12531366 chr7:91683849 C/G cg22709100 chr7:91322751 NA 0.29 4.92 0.4 2.71e-6 Breast cancer; TGCT cis rs78487399 0.908 rs12471686 chr2:43831083 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1865760 0.865 rs9467651 chr6:25958257 C/G cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs478607 0.831 rs3825074 chr11:64415767 G/A cg19395706 chr11:64412079 NRXN2 0.48 4.84 0.4 3.8e-6 Urate levels; TGCT cis rs3782455 1.000 rs117470230 chr12:114403053 G/C cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2455799 0.613 rs12491914 chr3:15808672 A/C cg16303742 chr3:15540471 COLQ -0.25 -4.74 -0.39 5.76e-6 Mean platelet volume; TGCT cis rs10791097 1.000 rs10791097 chr11:130718630 G/T cg05962950 chr11:130786565 SNX19 -0.74 -7.04 -0.53 1.15e-10 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs10435719 0.753 rs9694940 chr8:11789858 G/C cg15556689 chr8:8085844 FLJ10661 0.74 7.04 0.53 1.17e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs4851254 0.961 rs13011181 chr2:100732446 T/C cg22139774 chr2:100720529 AFF3 -0.4 -4.74 -0.39 5.7e-6 Intelligence (multi-trait analysis); TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg04234412 chr22:24373322 LOC391322 -0.85 -8.55 -0.61 3.95e-14 Urinary 1,3-butadiene metabolite levels in smokers; TGCT trans rs4919669 0.546 rs4919656 chr10:104282861 G/A cg19053889 chr7:1098703 C7orf50;GPR146 0.51 6.78 0.52 4.25e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs6988636 0.710 rs17315999 chr8:124153763 A/G cg23067535 chr8:124195133 FAM83A -0.37 -4.59 -0.38 1.07e-5 Urinary uromodulin levels; TGCT cis rs1218582 0.772 rs10908448 chr1:154882544 A/G cg03351412 chr1:154909251 PMVK -0.52 -4.85 -0.4 3.55e-6 Prostate cancer; TGCT cis rs2239547 0.657 rs2072391 chr3:52862200 C/T cg10802521 chr3:52805072 NEK4 -0.62 -5.85 -0.47 4.1e-8 Schizophrenia; TGCT cis rs950169 0.526 rs698620 chr15:85177208 G/A cg11189052 chr15:85197271 WDR73 -0.73 -7.16 -0.54 6.16e-11 Schizophrenia; TGCT cis rs7618915 0.501 rs55678971 chr3:52717229 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.59 5.6 0.45 1.31e-7 Bipolar disorder; TGCT cis rs13108904 0.901 rs1680073 chr4:1280337 G/A cg08683831 chr4:1404607 NA -0.46 -4.43 -0.37 2.01e-5 Obesity-related traits; TGCT trans rs1814175 0.669 rs12416837 chr11:49669761 G/T cg03929089 chr4:120376271 NA -0.6 -7.01 -0.53 1.34e-10 Height; TGCT cis rs2742417 1.000 rs2742420 chr3:45732237 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.67 -0.45 9.39e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs8072100 1.000 rs7210738 chr17:45757598 G/A cg08085267 chr17:45401833 C17orf57 0.47 5.13 0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs3015497 0.789 rs923908 chr14:51123595 C/T cg04730355 chr14:51134070 SAV1 -0.66 -6.46 -0.5 2.19e-9 Mean platelet volume; TGCT cis rs600231 0.651 rs2846862 chr11:65219790 A/G cg17120908 chr11:65337727 SSSCA1 -0.52 -4.68 -0.39 7.41e-6 Bone mineral density; TGCT cis rs2120019 1.000 rs7175720 chr15:75348962 C/G cg11632617 chr15:75315747 PPCDC 0.33 4.77 0.39 5.14e-6 Blood trace element (Zn levels); TGCT cis rs3026101 0.671 rs8067917 chr17:5278307 G/A cg25236894 chr17:5323110 RPAIN;NUP88 0.47 4.57 0.38 1.18e-5 Body mass index; TGCT cis rs7267979 0.868 rs6107019 chr20:25233985 C/T cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs250677 0.652 rs250670 chr5:148446646 G/T cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs2115630 0.645 rs1107179 chr15:85198362 A/C cg17173187 chr15:85201210 NMB 0.47 5.71 0.46 7.96e-8 P wave terminal force; TGCT cis rs1008375 0.966 rs6839660 chr4:17667987 C/T cg10189774 chr4:17578691 LAP3 0.51 4.7 0.39 6.71e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11098499 0.954 rs3733524 chr4:120423729 T/C cg09307838 chr4:120376055 NA 0.67 6.3 0.49 4.63e-9 Corneal astigmatism; TGCT cis rs4689592 0.503 rs4689064 chr4:7055603 A/G cg02503808 chr4:7069936 GRPEL1 -0.96 -8.24 -0.59 2.12e-13 Monocyte percentage of white cells; TGCT cis rs1843834 0.539 rs1494109 chr2:225441833 G/A cg22455342 chr2:225449267 CUL3 1.04 10.75 0.69 1.87e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs7246657 0.722 rs13744 chr19:38077912 C/T cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs10504229 1.000 rs57261109 chr8:58172152 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.962 rs4699605 chr4:99064379 A/G cg18180107 chr4:99064573 C4orf37 0.55 4.48 0.37 1.64e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.877 rs7728736 chr5:93404277 C/T cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs2075371 0.829 rs11770521 chr7:133936251 A/C cg11752832 chr7:134001865 SLC35B4 0.66 5.51 0.44 1.95e-7 Mean platelet volume; TGCT cis rs2067615 0.524 rs754184 chr12:107117521 A/G cg15890332 chr12:107067104 RFX4 0.26 5.3 0.43 5.03e-7 Heart rate; TGCT cis rs7843479 0.601 rs3824338 chr8:21864540 A/C cg17168535 chr8:21777572 XPO7 0.8 8.05 0.59 5.9e-13 Mean corpuscular volume; TGCT cis rs1062177 1.000 rs12518722 chr5:151231460 A/G cg00977110 chr5:151150581 G3BP1 0.4 4.5 0.38 1.51e-5 Preschool internalizing problems; TGCT cis rs9486715 0.793 rs2499777 chr6:97013814 T/C cg18709589 chr6:96969512 KIAA0776 -0.86 -8.45 -0.6 6.73e-14 Headache; TGCT cis rs588177 0.522 rs34358026 chr11:64015422 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.84 7.09 0.54 9.2e-11 High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg08280861 chr8:58055591 NA 0.36 4.98 0.41 2.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs4700695 0.841 rs784276 chr5:65317332 A/T cg21114390 chr5:65439923 SFRS12 0.6 4.53 0.38 1.36e-5 Facial morphology (factor 19); TGCT cis rs3858526 0.606 rs10838883 chr11:5952147 G/A cg05234568 chr11:5960015 NA 0.57 6.13 0.48 1.06e-8 DNA methylation (variation); TGCT cis rs10782582 0.586 rs1796813 chr1:76400403 G/A cg10523679 chr1:76189770 ACADM -0.56 -5.04 -0.41 1.6e-6 Daytime sleep phenotypes; TGCT cis rs4499344 0.604 rs259275 chr19:33159693 A/G cg26639809 chr19:33781782 NA 0.22 4.47 0.37 1.75e-5 Mean platelet volume; TGCT cis rs1552244 0.572 rs67227131 chr3:10172744 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.98 5.69 0.45 8.72e-8 Alzheimer's disease; TGCT cis rs13108904 0.901 rs4516656 chr4:1279860 A/G cg13395646 chr4:1353034 KIAA1530 -0.39 -4.96 -0.41 2.3e-6 Obesity-related traits; TGCT cis rs6748734 1.000 rs4675860 chr2:241840417 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -6.35 -0.5 3.72e-9 Urinary metabolites; TGCT cis rs9303401 0.625 rs34963822 chr17:56988424 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.16 0.48 9.11e-9 Cognitive test performance; TGCT cis rs2032447 0.672 rs9379811 chr6:25955197 G/C cg03517284 chr6:25882590 NA -0.65 -5.74 -0.46 6.73e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.753 rs6826709 chr4:98714553 C/G cg05340658 chr4:99064831 C4orf37 0.49 5.71 0.46 7.99e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6969780 0.722 rs983185 chr7:27188607 G/A cg06942814 chr7:27170819 HOXA4 -0.4 -4.45 -0.37 1.92e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs2832191 0.967 rs2832216 chr21:30521921 C/T cg24692254 chr21:30365293 RNF160 0.82 9.12 0.63 1.67e-15 Dental caries; TGCT cis rs7267979 0.932 rs6115215 chr20:25562500 C/T cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs981844 0.683 rs1037647 chr4:154737991 A/G cg14289246 chr4:154710475 SFRP2 -1.0 -9.32 -0.64 5.46e-16 Response to statins (LDL cholesterol change); TGCT cis rs7777484 0.534 rs2533888 chr7:2831083 T/C cg25467336 chr7:2757616 NA -0.25 -4.64 -0.38 8.88e-6 Height; TGCT cis rs644799 1.000 rs543530 chr11:95545170 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7772486 0.875 rs932522 chr6:146374026 A/G cg23711669 chr6:146136114 FBXO30 -0.9 -9.98 -0.67 1.41e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs4478858 0.647 rs11581476 chr1:31717675 C/T cg07478791 chr1:31886160 SERINC2 -0.48 -4.6 -0.38 1.03e-5 Alcohol dependence; TGCT cis rs9443645 0.869 rs6913028 chr6:79513590 C/T cg09184832 chr6:79620586 NA -0.46 -5.01 -0.41 1.83e-6 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs514833 chr11:68657734 C/T cg06028808 chr11:68637592 NA 0.51 6.54 0.51 1.48e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7428 0.545 rs7572750 chr2:85552186 C/A cg24342717 chr2:85555507 TGOLN2 -0.49 -7.83 -0.58 1.88e-12 Ear protrusion; TGCT cis rs597539 0.552 rs10792006 chr11:68722306 T/C cg21963583 chr11:68658836 MRPL21 -0.25 -4.56 -0.38 1.2e-5 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2404602 1.000 rs12441433 chr15:76816015 G/A cg26408565 chr15:76604113 ETFA -0.41 -5.3 -0.43 5.13e-7 Blood metabolite levels; TGCT cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg22168489 chr12:122356033 WDR66 0.23 5.52 0.44 1.91e-7 Mean corpuscular volume; TGCT cis rs60871478 0.947 rs62432862 chr7:807719 G/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.6 0.38 1.04e-5 Cerebrospinal P-tau181p levels; TGCT cis rs10883723 0.773 rs11191313 chr10:104278618 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.79 7.79 0.57 2.25e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs61935443 0.832 rs11107768 chr12:95274182 A/T cg21533806 chr12:95267307 NA -0.52 -4.64 -0.38 8.68e-6 Schizophrenia; TGCT cis rs6490294 0.898 rs4767202 chr12:112354075 T/C cg10833066 chr12:111807467 FAM109A 0.39 5.65 0.45 1.03e-7 Mean platelet volume; TGCT cis rs9677476 0.863 rs3731775 chr2:232063578 G/A cg07929768 chr2:232055508 NA 0.31 4.49 0.37 1.61e-5 Food antigen IgG levels; TGCT cis rs6089584 1.000 rs6089585 chr20:60564395 G/A cg13770153 chr20:60521292 NA -0.44 -5.69 -0.46 8.52e-8 Body mass index; TGCT cis rs614226 1.000 rs563920 chr12:121017439 A/G cg01236616 chr12:121019343 POP5 1.29 14.01 0.78 2.51e-27 Type 1 diabetes nephropathy; TGCT trans rs9929218 0.551 rs2296405 chr16:68721470 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.63 -8.27 -0.6 1.74e-13 Colorectal cancer; TGCT cis rs56235845 0.694 rs11949401 chr5:176765989 A/G cg06060754 chr5:176797920 RGS14 0.4 6.33 0.49 3.99e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs9902453 0.934 rs4427857 chr17:28457989 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs7666738 0.830 rs4699589 chr4:98973889 A/G cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10256972 0.713 rs10435026 chr7:1065948 A/G cg09174653 chr7:1063357 C7orf50;MIR339 -0.22 -4.44 -0.37 2e-5 Longevity;Endometriosis; TGCT cis rs7705042 0.686 rs62381975 chr5:141513018 G/A cg07392085 chr5:141489673 NDFIP1 -0.34 -4.54 -0.38 1.34e-5 Asthma; TGCT cis rs2033711 0.870 rs1051500 chr19:58944402 A/G cg04608855 chr19:58913158 NA 0.58 5.74 0.46 6.86e-8 Uric acid clearance; TGCT trans rs561341 1.000 rs4795670 chr17:30244839 T/C cg20587970 chr11:113659929 NA -0.97 -12.13 -0.74 8.27e-23 Hip circumference adjusted for BMI; TGCT cis rs13177918 0.677 rs4841 chr5:149826526 C/T cg14059543 chr5:149831962 NA -0.71 -9.35 -0.64 4.68e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7677751 0.537 rs6554164 chr4:55106695 T/C cg17187183 chr4:55093834 PDGFRA 0.35 4.48 0.37 1.64e-5 Corneal astigmatism; TGCT cis rs600231 0.651 rs2846862 chr11:65219790 A/G cg21890820 chr11:65308645 LTBP3 0.38 4.7 0.39 6.92e-6 Bone mineral density; TGCT cis rs10875746 0.669 rs11168510 chr12:48685555 A/G cg20731937 chr12:48336164 NA 0.59 4.49 0.37 1.61e-5 Longevity (90 years and older); TGCT cis rs17401966 0.931 rs61778401 chr1:10426474 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.03e-7 Hepatocellular carcinoma; TGCT cis rs854765 0.551 rs56886154 chr17:17831473 C/A cg09796270 chr17:17721594 SREBF1 0.27 5.55 0.45 1.69e-7 Total body bone mineral density; TGCT cis rs10089 1.000 rs4836360 chr5:127458161 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.17 0.59 2.99e-13 Ileal carcinoids; TGCT cis rs6088590 0.687 rs6088580 chr20:33285053 G/C cg08999081 chr20:33150536 PIGU 0.27 5.01 0.41 1.81e-6 Coronary artery disease; TGCT cis rs9926296 0.529 rs7195906 chr16:89806347 A/T cg27121462 chr16:89883253 FANCA 0.81 8.9 0.62 5.56e-15 Vitiligo; TGCT cis rs4845570 1.000 rs3811415 chr1:151763767 C/T cg07092448 chr1:151763213 TDRKH -1.12 -8.62 -0.61 2.64e-14 Coronary artery disease; TGCT cis rs2486288 0.656 rs1060896 chr15:45554267 C/A cg14582100 chr15:45693742 SPATA5L1 -0.44 -5.28 -0.43 5.62e-7 Glomerular filtration rate; TGCT cis rs8016982 0.633 rs55822231 chr14:81708677 C/T cg01989461 chr14:81687754 GTF2A1 0.84 8.66 0.61 2.06e-14 Schizophrenia; TGCT cis rs858239 0.539 rs6955969 chr7:23186699 C/T cg05602783 chr7:23145260 KLHL7 -0.6 -4.74 -0.39 5.86e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs644799 0.525 rs3016206 chr11:95536724 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.8 8.76 0.62 1.21e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6867913 0.709 rs2338874 chr5:141466926 G/A cg01169021 chr5:140792918 PCDHGA4;PCDHGA6;PCDHGA9;PCDHGA1;PCDHGA8;PCDHGA5;PCDHGB1;PCDHGA10;PCDHGB4;PCDHGA3;PCDHGA2;PCDHGB6;PCDHGA7;PCDHGB2;PCDHGB5;PCDHGB3 -0.41 -5.09 -0.42 1.31e-6 Asthma; TGCT cis rs9303401 0.615 rs7502342 chr17:56922629 C/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs3096299 0.967 rs2965830 chr16:89460290 T/C cg06640241 chr16:89574553 SPG7 0.66 6.32 0.49 4.33e-9 Multiple myeloma (IgH translocation); TGCT cis rs1048238 0.846 rs945420 chr1:16345208 G/A cg22431228 chr1:16359049 CLCNKA -0.29 -6.2 -0.49 7.76e-9 Systolic blood pressure; TGCT cis rs11190604 1.000 rs11190601 chr10:102296730 A/G cg23241863 chr10:102295624 HIF1AN 0.67 5.12 0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1158570 0.773 rs6984963 chr8:131332096 A/G cg16277922 chr8:131349729 ASAP1 0.48 7.2 0.54 5.06e-11 Platelet count; TGCT cis rs7267979 0.966 rs6050611 chr20:25414419 A/G cg14121845 chr20:25566513 NINL 0.48 5.06 0.41 1.45e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11761231 1.000 rs11761231 chr7:131370039 A/G cg23399222 chr7:130417715 KLF14 0.24 4.52 0.38 1.42e-5 Rheumatoid arthritis; TGCT cis rs6450176 1.000 rs4588541 chr5:53300640 A/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.1 -0.42 1.23e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg02073558 chr3:44770973 ZNF501 0.7 6.99 0.53 1.49e-10 Depressive symptoms; TGCT cis rs4746059 0.516 rs4747080 chr10:72466545 A/G cg03087610 chr10:71892362 AIFM2 0.54 4.78 0.39 4.85e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 1.000 rs12213740 chr6:86656733 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg08439880 chr3:133502540 NA -0.28 -5.15 -0.42 9.73e-7 Iron status biomarkers; TGCT cis rs7044106 0.791 rs7036196 chr9:123479457 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 6.99 0.53 1.48e-10 Hip circumference adjusted for BMI; TGCT cis rs12210905 1.000 rs1102557 chr6:27149794 C/A cg08851530 chr6:28072375 NA -1.12 -5.43 -0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs9910055 0.639 rs11656871 chr17:42269141 G/C cg13607699 chr17:42295918 UBTF 0.6 5.48 0.44 2.23e-7 Total body bone mineral density; TGCT cis rs6951245 0.882 rs10256720 chr7:1210825 C/G cg00738919 chr7:1100172 C7orf50 0.47 4.47 0.37 1.72e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4718428 0.705 rs11028 chr7:66276217 T/C cg18252515 chr7:66147081 NA -0.59 -4.51 -0.38 1.47e-5 Corneal structure; TGCT cis rs910316 1.000 rs10136948 chr14:75511075 C/T cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs910316 0.763 rs175450 chr14:75590340 G/A cg11812906 chr14:75593930 NEK9 -0.63 -5.81 -0.46 4.98e-8 Height; TGCT cis rs3785574 0.962 rs4480868 chr17:61788859 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.57 0.45 1.52e-7 Height; TGCT cis rs10504229 0.679 rs16921677 chr8:58052431 T/C cg08280861 chr8:58055591 NA 0.36 5.14 0.42 1.03e-6 Developmental language disorder (linguistic errors); TGCT cis rs2469997 0.925 rs2470005 chr8:120358483 T/G cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg05590025 chr7:65112418 INTS4L2 -0.76 -4.44 -0.37 1.96e-5 Diabetic kidney disease; TGCT cis rs1008375 1.000 rs55939327 chr4:17642937 T/A cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13108904 1.000 rs13108904 chr4:1291113 G/T cg03303774 chr4:1407052 NA 0.29 4.5 0.37 1.52e-5 Obesity-related traits; TGCT cis rs7119 0.651 rs12915057 chr15:77847745 C/A cg27398640 chr15:77910606 LINGO1 -0.28 -5.11 -0.42 1.21e-6 Type 2 diabetes; TGCT cis rs6688613 0.959 rs112416021 chr1:166944745 T/C cg07049167 chr1:166818506 POGK 0.22 4.55 0.38 1.28e-5 Refractive astigmatism; TGCT cis rs2013441 1.000 rs2703810 chr17:20113715 C/T cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs7552404 1.000 rs7552404 chr1:76135946 A/G cg03433033 chr1:76189801 ACADM 0.84 10.07 0.67 8.62e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9388451 0.839 rs9401845 chr6:126104118 A/G cg05901451 chr6:126070800 HEY2 -1.0 -14.45 -0.79 2.37e-28 Brugada syndrome; TGCT cis rs854765 0.547 rs8069811 chr17:17922280 G/A cg04398451 chr17:18023971 MYO15A -0.31 -5.05 -0.41 1.56e-6 Total body bone mineral density; TGCT cis rs5769765 1.000 rs5769760 chr22:50259696 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.71 0.72 8.52e-22 Schizophrenia; TGCT trans rs117132860 0.661 rs10224957 chr7:17117288 T/C cg25519926 chr7:130132360 MEST;MESTIT1 0.95 6.72 0.52 5.93e-10 Cutaneous squamous cell carcinoma; TGCT cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg11644478 chr21:40555479 PSMG1 1.01 10.35 0.68 1.81e-18 Cognitive function; TGCT cis rs4788570 0.584 rs11862723 chr16:71704222 T/C cg06353428 chr16:71660113 MARVELD3 1.56 12.54 0.75 8.54e-24 Intelligence (multi-trait analysis); TGCT cis rs514406 0.536 rs878957 chr1:53197559 C/T cg08859206 chr1:53392774 SCP2 0.38 5.39 0.44 3.49e-7 Monocyte count; TGCT trans rs2688608 0.869 rs2250140 chr10:75612881 T/C cg13918328 chr10:52500089 ASAH2B 0.68 6.95 0.53 1.87e-10 Inflammatory bowel disease; TGCT cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg18654377 chr3:49208889 KLHDC8B -0.47 -6.21 -0.49 7.35e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7916697 0.947 rs1900004 chr10:70000881 C/T cg18338521 chr10:69995036 NA -0.28 -4.47 -0.37 1.75e-5 Optic disc area; TGCT cis rs7677751 0.708 rs6554160 chr4:55077549 T/A cg17187183 chr4:55093834 PDGFRA 0.48 6.31 0.49 4.41e-9 Corneal astigmatism; TGCT cis rs6500602 0.674 rs7191664 chr16:4541924 T/C cg08645402 chr16:4508243 NA 0.2 5.01 0.41 1.86e-6 Schizophrenia; TGCT cis rs6681544 0.544 rs3790912 chr1:82377091 C/T cg04226724 chr1:82268649 LPHN2 0.47 4.87 0.4 3.28e-6 Metabolite levels (X-11787); TGCT cis rs35306767 0.903 rs35957139 chr10:884889 C/T cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT cis rs11214589 0.774 rs7107223 chr11:113255574 A/T cg14159747 chr11:113255604 NA 0.36 4.52 0.38 1.41e-5 Neuroticism; TGCT cis rs2730260 0.537 rs73169239 chr7:158884305 C/A cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs9640161 0.789 rs28432021 chr7:150046235 G/C cg10018233 chr7:150070692 REPIN1 0.31 4.55 0.38 1.25e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs6542838 0.588 rs4851174 chr2:99530113 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.53 -4.99 -0.41 2.01e-6 Fear of minor pain; TGCT cis rs5750830 0.594 rs9611169 chr22:39783027 C/T cg01416388 chr22:39784598 NA -0.61 -6.26 -0.49 5.88e-9 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg15242686 chr22:24348715 GSTTP1 0.42 5.62 0.45 1.22e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4730250 0.707 rs1981696 chr7:106794100 C/T cg02696742 chr7:106810147 HBP1 0.71 5.67 0.45 9.61e-8 Osteoarthritis; TGCT cis rs68170813 0.559 rs1018946 chr7:106851754 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs904251 0.965 rs1317563 chr6:37451854 G/T cg08126542 chr6:37504118 NA -0.36 -4.76 -0.39 5.3e-6 Cognitive performance; TGCT cis rs7000551 0.663 rs7827118 chr8:22334669 T/G cg12081754 chr8:22256438 SLC39A14 0.28 4.5 0.37 1.54e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2013441 1.000 rs3850784 chr17:20185030 A/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs10746514 0.833 rs10864720 chr1:232271232 C/T cg09506761 chr1:232265262 NA -0.52 -5.41 -0.44 3.16e-7 Response to statin therapy; TGCT cis rs72781680 1.000 rs72781680 chr2:24238928 C/T cg08917208 chr2:24149416 ATAD2B 0.83 5.08 0.42 1.35e-6 Lymphocyte counts; TGCT cis rs6684514 0.961 rs12126696 chr1:156241348 C/T cg20302342 chr1:156215951 PAQR6 0.36 4.75 0.39 5.6e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs16854884 0.770 rs4450810 chr3:143809091 C/A cg06585982 chr3:143692056 C3orf58 0.57 4.49 0.37 1.63e-5 Economic and political preferences (feminism/equality); TGCT cis rs394563 0.591 rs11155641 chr6:149648595 G/A cg03678062 chr6:149772716 ZC3H12D 0.38 4.83 0.4 3.99e-6 Dupuytren's disease; TGCT cis rs10507380 0.824 rs75922600 chr13:27914656 C/T cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs595982 0.527 rs35023389 chr19:49377873 G/A cg17863274 chr19:49399704 TULP2 -0.55 -7.9 -0.58 1.31e-12 Red cell distribution width; TGCT cis rs12908161 0.650 rs182517 chr15:85389631 G/A cg11189052 chr15:85197271 WDR73 0.64 5.16 0.42 9.65e-7 Schizophrenia; TGCT cis rs3733585 0.746 rs4318650 chr4:10016868 T/C cg11266682 chr4:10021025 SLC2A9 0.69 9.1 0.63 1.93e-15 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1008375 0.966 rs2315645 chr4:17579678 G/C cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2594989 0.673 rs62245959 chr3:11601797 G/T cg00170343 chr3:11313890 ATG7 -0.71 -4.91 -0.4 2.87e-6 Circulating chemerin levels; TGCT cis rs764284 0.506 rs9379980 chr6:27306518 C/T cg02458000 chr6:26745757 NA -0.48 -4.49 -0.37 1.6e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2153535 0.505 rs1335629 chr6:8491863 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs6964587 0.934 rs7793861 chr7:91742728 C/G cg17063962 chr7:91808500 NA 0.87 9.34 0.64 4.87e-16 Breast cancer; TGCT cis rs826838 0.585 rs4363678 chr12:38624514 G/A cg26384229 chr12:38710491 ALG10B 0.56 5.11 0.42 1.21e-6 Heart rate; TGCT cis rs7666738 0.830 rs4699595 chr4:99012827 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7119 0.717 rs12904212 chr15:77815833 C/A cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs6582630 0.555 rs7978749 chr12:38527141 G/T cg26384229 chr12:38710491 ALG10B 0.85 7.74 0.57 3.08e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.710 rs7674407 chr4:98838522 A/G cg05340658 chr4:99064831 C4orf37 0.53 6.17 0.48 8.71e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs1448094 0.533 rs2169572 chr12:86170370 G/T cg02569458 chr12:86230093 RASSF9 -0.39 -4.58 -0.38 1.14e-5 Major depressive disorder; TGCT cis rs1577917 0.917 rs1584273 chr6:86524577 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs11785400 1.000 rs13266249 chr8:143732433 A/C cg24634471 chr8:143751801 JRK 0.54 5.85 0.46 4.19e-8 Schizophrenia; TGCT trans rs1814175 0.654 rs7482446 chr11:49779020 A/G cg11707556 chr5:10655725 ANKRD33B -0.38 -7.76 -0.57 2.75e-12 Height; TGCT cis rs7659604 1.000 rs7659943 chr4:122665560 C/T cg19748678 chr4:122722346 EXOSC9 0.53 5.01 0.41 1.82e-6 Type 2 diabetes; TGCT cis rs7666738 0.570 rs1921415 chr4:99093804 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.75 0.39 5.61e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.909 rs35111518 chr4:120440682 A/G cg09307838 chr4:120376055 NA 0.69 6.53 0.51 1.49e-9 Corneal astigmatism; TGCT cis rs7811142 0.830 rs11761253 chr7:99939321 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.14 0.42 1.06e-6 Platelet count; TGCT cis rs11098499 0.588 rs2389874 chr4:120554991 A/G cg09307838 chr4:120376055 NA -0.57 -5.35 -0.43 4.16e-7 Corneal astigmatism; TGCT cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg10295955 chr4:187884368 NA -0.97 -14.62 -0.8 9.35e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs2898681 0.519 rs6554057 chr4:53730147 A/T cg00791764 chr4:53727839 RASL11B 0.54 4.58 0.38 1.1e-5 Optic nerve measurement (cup area); TGCT cis rs198851 0.736 rs198846 chr6:26107463 A/G cg11837274 chr6:26034134 HIST1H2AB 0.71 4.55 0.38 1.28e-5 Red cell distribution width;High light scatter reticulocyte percentage of red cells;Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs698813 0.604 rs2340814 chr2:44490977 C/T cg00619915 chr2:44497795 NA -0.24 -5.5 -0.44 2.05e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs7191439 0.858 rs6500489 chr16:88772046 T/C cg27087555 chr16:88793112 FAM38A -0.6 -6.37 -0.5 3.36e-9 Plateletcrit; TGCT cis rs2172802 0.659 rs2343251 chr4:62492671 C/A cg04118610 chr4:62707027 LPHN3 0.43 4.66 0.39 8.13e-6 Partial epilepsies; TGCT cis rs3858526 1.000 rs10838909 chr11:5960490 G/A cg13902645 chr11:5959945 NA -0.44 -4.72 -0.39 6.39e-6 DNA methylation (variation); TGCT cis rs17253792 0.822 rs28681420 chr14:56088403 G/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs1129187 0.902 rs10948059 chr6:42928461 C/T cg13397359 chr6:42928475 GNMT 0.84 8.18 0.59 2.89e-13 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs763121 0.819 rs4560233 chr22:38982442 A/T cg06022373 chr22:39101656 GTPBP1 0.77 7.39 0.55 1.94e-11 Menopause (age at onset); TGCT cis rs7726839 0.574 rs11134149 chr5:637277 A/G cg16624210 chr5:671434 TPPP 0.38 4.63 0.38 9.02e-6 Obesity-related traits; TGCT cis rs17221829 0.931 rs35892874 chr11:89452677 C/T cg02982614 chr11:89391479 FOLH1B -0.29 -4.95 -0.41 2.4e-6 Anxiety in major depressive disorder; TGCT cis rs7666738 0.753 rs28390295 chr4:99028497 C/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9291683 0.588 rs3756237 chr4:10013378 G/A cg02734326 chr4:10020555 SLC2A9 0.38 4.56 0.38 1.22e-5 Bone mineral density; TGCT cis rs12477438 0.765 rs10193039 chr2:99692373 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.64 -5.45 -0.44 2.61e-7 Chronic sinus infection; TGCT cis rs28735056 0.967 rs56071379 chr18:77647406 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.54 -0.45 1.75e-7 Schizophrenia; TGCT cis rs6570726 0.935 rs367643 chr6:145859602 A/C cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1801251 1.000 rs1801251 chr2:233633460 G/A cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT trans rs12339966 0.581 rs62529408 chr9:11331268 T/G cg03488587 chr11:64876988 C11orf2 0.31 6.62 0.51 9.51e-10 Systolic blood pressure; TGCT cis rs933688 0.938 rs6866923 chr5:90669352 A/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 10.13 0.67 6.16e-18 Smoking behavior; TGCT cis rs2933343 0.859 rs789247 chr3:128580585 C/A cg11901034 chr3:128598214 ACAD9 -0.62 -5.16 -0.42 9.47e-7 IgG glycosylation; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg11883238 chr10:62676418 RHOBTB1 -0.7 -6.8 -0.52 4.03e-10 Follicular lymphoma; TGCT cis rs9409154 0.823 rs7467175 chr9:118109239 C/T cg14094498 chr9:119000864 PAPPA 0.26 4.76 0.39 5.32e-6 Visceral adipose tissue adjusted for BMI; TGCT cis rs9311474 0.607 rs34005367 chr3:52558904 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.91 0.4 2.75e-6 Electroencephalogram traits; TGCT cis rs62064224 0.553 rs6505297 chr17:30765767 A/G cg18200150 chr17:30822561 MYO1D 0.44 5.27 0.43 5.73e-7 Schizophrenia; TGCT cis rs858239 0.600 rs7788821 chr7:23133645 A/T cg05602783 chr7:23145260 KLHL7 -0.58 -4.85 -0.4 3.68e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs35146811 0.695 rs1727132 chr7:99812297 T/C cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs6912958 0.781 rs6916732 chr6:88259225 C/T cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs4273100 1.000 rs4273100 chr17:19153417 T/C cg01534423 chr17:18965556 NA 0.92 5.56 0.45 1.55e-7 Schizophrenia; TGCT cis rs763121 0.853 rs7289855 chr22:39042221 G/T cg06022373 chr22:39101656 GTPBP1 0.76 7.22 0.54 4.54e-11 Menopause (age at onset); TGCT cis rs853679 0.515 rs4580862 chr6:28367663 T/C cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Depression; TGCT cis rs1692580 0.807 rs12138597 chr1:2189477 T/C cg21194808 chr1:2205498 SKI 0.29 5.78 0.46 5.71e-8 Coronary artery disease; TGCT cis rs7666738 0.830 rs6832209 chr4:98994120 A/G cg18180107 chr4:99064573 C4orf37 0.51 4.68 0.39 7.37e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs17471911 0.708 rs10466169 chr10:100772791 C/T cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs3816788 0.792 rs13257744 chr8:21872853 T/C cg17168535 chr8:21777572 XPO7 0.77 7.65 0.57 4.88e-12 Lung cancer in ever smokers; TGCT cis rs9811216 1.000 rs9868000 chr3:169510789 G/A cg08193579 chr3:169529701 LRRC34 0.29 4.48 0.37 1.68e-5 Neutrophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs11644362 0.966 rs11645507 chr16:12992570 C/A cg06890432 chr16:12997467 SHISA9 -0.61 -6.55 -0.51 1.41e-9 Positive affect;Subjective well-being; TGCT cis rs2120019 0.938 rs5020842 chr15:75322310 T/C cg09165964 chr15:75287851 SCAMP5 -1.2 -10.21 -0.68 3.83e-18 Blood trace element (Zn levels); TGCT cis rs1552244 1.000 rs7615646 chr3:10089773 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs208520 1.000 rs208521 chr6:66953625 C/T cg07460842 chr6:66804631 NA -0.83 -7.52 -0.56 9.8e-12 Exhaled nitric oxide output; TGCT cis rs12220238 1.000 rs10824076 chr10:75886956 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7267979 1.000 rs10966 chr20:25282944 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2816062 0.813 rs2816050 chr1:18894432 A/G cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.04e-27 Urate levels in lean individuals; TGCT trans rs1814175 0.765 rs1722003 chr11:49895896 G/A cg03929089 chr4:120376271 NA -0.72 -8.15 -0.59 3.33e-13 Height; TGCT cis rs7666738 0.830 rs10028692 chr4:98962585 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs12908161 1.000 rs17600551 chr15:85319258 A/G cg17173187 chr15:85201210 NMB 0.57 6.4 0.5 2.89e-9 Schizophrenia; TGCT cis rs9388451 0.626 rs2875881 chr6:126072853 C/G cg05901451 chr6:126070800 HEY2 -1.04 -13.0 -0.76 6.65e-25 Brugada syndrome; TGCT cis rs11671005 0.735 rs3826682 chr19:58918748 C/T cg13877915 chr19:58951672 ZNF132 0.63 4.92 0.4 2.74e-6 Mean platelet volume; TGCT cis rs1355223 0.583 rs1549789 chr11:34867947 G/A cg24088639 chr11:34937564 PDHX;APIP -0.5 -4.51 -0.38 1.45e-5 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs11690935 0.655 rs17614941 chr2:172541378 A/G cg13550731 chr2:172543902 DYNC1I2 0.73 6.37 0.5 3.29e-9 Schizophrenia; TGCT cis rs16971465 0.850 rs62053226 chr16:73022013 C/T cg01557791 chr16:72042693 DHODH 0.91 4.54 0.38 1.29e-5 Schizophrenia; TGCT cis rs10791097 0.690 rs12286234 chr11:130730528 T/C cg14779329 chr11:130786720 SNX19 0.25 4.44 0.37 1.96e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2692947 0.759 rs2692937 chr2:96751871 G/A cg23100626 chr2:96804247 ASTL 0.4 4.75 0.39 5.55e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs66782572 1 rs66782572 chr3:52567617 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.87 0.4 3.31e-6 Hemoglobin concentration; TGCT cis rs7568458 0.846 rs10179195 chr2:85762761 A/G cg02493740 chr2:85810744 VAMP5 -0.27 -4.97 -0.41 2.2e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs1008375 0.966 rs4698619 chr4:17580955 G/A cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3733585 0.805 rs882222 chr4:9981294 G/A cg11266682 chr4:10021025 SLC2A9 0.62 8.63 0.61 2.51e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9322193 0.923 rs2297932 chr6:150039361 C/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs11249608 0.548 rs6867208 chr5:178455575 G/A cg21905437 chr5:178450457 ZNF879 0.43 4.5 0.37 1.53e-5 Pubertal anthropometrics; TGCT cis rs427394 0.659 rs274717 chr5:6721067 C/T cg10857441 chr5:6722123 POLS 0.28 5.86 0.47 3.82e-8 Menopause (age at onset); TGCT cis rs1857353 1.000 rs1857354 chr1:75902948 C/T cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs17401966 0.867 rs7546364 chr1:10418815 G/A cg19773385 chr1:10388646 KIF1B -0.23 -5.38 -0.44 3.57e-7 Hepatocellular carcinoma; TGCT cis rs1801251 1.000 rs2592105 chr2:233645968 C/G cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs8017423 1.000 rs2183189 chr14:90670057 A/G cg04374321 chr14:90722782 PSMC1 0.77 7.95 0.58 9.78e-13 Mortality in heart failure; TGCT cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg26818010 chr10:134567672 INPP5A -0.35 -4.76 -0.39 5.21e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7617773 0.780 rs11714944 chr3:48366971 C/A cg11946769 chr3:48343235 NME6 0.8 6.91 0.53 2.26e-10 Coronary artery disease; TGCT cis rs2486288 0.656 rs1706770 chr15:45575062 T/C cg26924012 chr15:45694286 SPATA5L1 -0.84 -9.07 -0.63 2.28e-15 Glomerular filtration rate; TGCT cis rs2050392 0.517 rs687036 chr10:30761249 G/A cg18806716 chr10:30721971 MAP3K8 -0.55 -6.7 -0.52 6.64e-10 Inflammatory bowel disease; TGCT cis rs7119167 0.813 rs7101831 chr11:73106690 T/C cg17517138 chr11:73019481 ARHGEF17 0.57 4.44 0.37 2e-5 Blood protein levels; TGCT cis rs644799 0.965 rs2508713 chr11:95547927 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs28386778 0.799 rs2727322 chr17:61921706 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg03264133 chr6:25882463 NA -0.49 -5.11 -0.42 1.17e-6 Height; TGCT cis rs12579753 1.000 rs34894912 chr12:82228721 A/G cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs9296092 0.522 rs62405955 chr6:33527176 T/C cg13560919 chr6:33536144 NA -0.23 -5.06 -0.41 1.49e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs67311347 1.000 rs9817142 chr3:40425774 C/A cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs7226408 0.948 rs17567496 chr18:34355579 T/G cg06757138 chr18:34340585 FHOD3 0.29 4.91 0.4 2.76e-6 Obesity-related traits; TGCT cis rs11671005 0.735 rs35652377 chr19:58929200 A/C cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT cis rs4242434 0.597 rs4066629 chr8:22529073 A/C cg03733263 chr8:22462867 KIAA1967 -1.03 -14.31 -0.79 4.99e-28 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs559406 0.501 rs2542167 chr18:12795849 A/T cg23598886 chr18:12777645 NA 0.35 4.44 0.37 1.97e-5 Psoriasis; TGCT cis rs9911578 1.000 rs2643119 chr17:56827760 G/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs2549003 1.000 rs2070726 chr5:131821738 C/A cg00255919 chr5:131827918 IRF1 0.2 4.65 0.39 8.22e-6 Asthma (sex interaction); TGCT cis rs3020736 0.500 rs5996109 chr22:42493098 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2019137 0.901 rs4849176 chr2:113977936 C/T cg27425262 chr2:113953981 PSD4;LOC440839 -0.48 -7.03 -0.53 1.25e-10 Lymphocyte counts; TGCT cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg26531700 chr6:26746687 NA -0.7 -6.84 -0.52 3.25e-10 Schizophrenia; TGCT cis rs3749237 1.000 rs11130214 chr3:49735746 C/G cg03060546 chr3:49711283 APEH -0.74 -7.7 -0.57 3.78e-12 Resting heart rate; TGCT trans rs797680 0.856 rs797672 chr1:93702119 A/T cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6570726 0.935 rs386344 chr6:145855622 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.42 0.55 1.64e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs910187 0.591 rs13041142 chr20:45788979 C/T cg27589058 chr20:45804311 EYA2 -0.37 -6.97 -0.53 1.67e-10 Migraine; TGCT cis rs12693043 0.727 rs2163236 chr2:175431707 C/G cg11778734 chr2:175439522 WIPF1 -0.37 -4.75 -0.39 5.51e-6 Urate levels (BMI interaction); TGCT cis rs12134133 0.688 rs6540875 chr1:207395031 C/T cg02152968 chr1:207494213 CD55 0.69 4.75 0.39 5.46e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs67311347 0.876 rs13068097 chr3:40504424 T/A cg17264618 chr3:40429014 ENTPD3 -0.33 -4.85 -0.4 3.66e-6 Renal cell carcinoma; TGCT cis rs2115630 1.000 rs1030863 chr15:85282635 C/T cg17173187 chr15:85201210 NMB -0.39 -4.76 -0.39 5.4e-6 P wave terminal force; TGCT cis rs7618915 0.501 rs7624716 chr3:52751534 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg26118208 chr10:134322334 NA 0.26 5.1 0.42 1.22e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17253792 0.822 rs112308750 chr14:56080073 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7818688 0.697 rs10504939 chr8:95983354 C/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs6570726 0.755 rs2092296 chr6:145893684 A/C cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs367615 0.591 rs4530812 chr5:108858587 A/C cg17395555 chr5:108820864 NA -0.27 -4.83 -0.4 3.88e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6988636 1.000 rs57165742 chr8:124184559 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs1348850 0.914 rs3902850 chr2:178315899 G/A cg22681709 chr2:178499509 PDE11A -0.35 -4.57 -0.38 1.18e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs1865760 0.566 rs2032449 chr6:26026599 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.44 0.56 1.47e-11 Height; TGCT cis rs9393777 0.528 rs7745603 chr6:27090404 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.54 -5.27 -0.43 5.73e-7 Intelligence (multi-trait analysis); TGCT cis rs17539620 0.624 rs62432740 chr6:154836054 C/T cg20019720 chr6:154832845 CNKSR3 0.57 5.02 0.41 1.72e-6 Lipoprotein (a) levels; TGCT cis rs1008375 1.000 rs9291659 chr4:17662360 A/C cg16339924 chr4:17578868 LAP3 0.56 4.86 0.4 3.51e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12477438 0.748 rs6712773 chr2:99585781 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs9926296 0.533 rs7190823 chr16:89866043 A/G cg27121462 chr16:89883253 FANCA 0.78 8.52 0.61 4.65e-14 Vitiligo; TGCT cis rs921968 0.608 rs678814 chr2:219359287 T/C cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs751728 0.648 rs6922275 chr6:33749739 G/A cg13859433 chr6:33739653 LEMD2 -0.32 -5.67 -0.45 9.47e-8 Crohn's disease; TGCT cis rs67311347 0.955 rs60554147 chr3:40472503 T/C cg17264618 chr3:40429014 ENTPD3 0.32 4.67 0.39 7.68e-6 Renal cell carcinoma; TGCT cis rs1670533 1.000 rs6836350 chr4:1069973 C/T cg27284194 chr4:1044797 NA 0.7 6.11 0.48 1.17e-8 Recombination rate (females); TGCT cis rs7258465 1.000 rs8103622 chr19:18572834 C/T cg22489759 chr19:18572700 ELL 0.2 4.46 0.37 1.81e-5 Breast cancer; TGCT cis rs35306767 0.761 rs11253558 chr10:1043983 T/C cg20503657 chr10:835505 NA 0.61 6.71 0.52 6.11e-10 Eosinophil percentage of granulocytes; TGCT cis rs7731657 0.537 rs10520092 chr5:130202197 C/T cg08523029 chr5:130500466 HINT1 0.55 4.63 0.38 8.92e-6 Fasting plasma glucose; TGCT cis rs10782582 0.609 rs5745347 chr1:76274520 C/T cg03433033 chr1:76189801 ACADM 0.48 4.86 0.4 3.48e-6 Daytime sleep phenotypes; TGCT cis rs2228479 0.850 rs62054609 chr16:89816569 C/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs17376456 0.877 rs10060462 chr5:93455073 C/T cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs9929218 0.551 rs4783663 chr16:68720271 T/C cg01251360 chr16:68772225 CDH1 -0.26 -4.59 -0.38 1.05e-5 Colorectal cancer; TGCT cis rs2233152 0.572 rs10411008 chr19:41297241 T/C cg11601297 chr19:41224147 ITPKC;ADCK4 0.49 4.73 0.39 5.94e-6 Kawasaki disease; TGCT cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg21724239 chr8:58056113 NA 0.39 5.24 0.43 6.73e-7 Developmental language disorder (linguistic errors); TGCT cis rs2760061 0.505 rs708109 chr1:228190657 C/T cg02753203 chr1:228287806 NA 0.39 7.63 0.57 5.36e-12 Diastolic blood pressure; TGCT cis rs1552244 0.938 rs7647987 chr3:10140696 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs6421571 0.565 rs10892263 chr11:118587319 T/C cg19308663 chr11:118741387 NA 0.25 4.48 0.37 1.66e-5 Primary biliary cholangitis; TGCT cis rs2469997 0.925 rs2470010 chr8:120359532 T/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg13695892 chr22:41940480 POLR3H 0.89 8.48 0.61 5.62e-14 Vitiligo; TGCT cis rs9399135 0.967 rs1590975 chr6:135352088 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.79 0.4 4.67e-6 Red blood cell count; TGCT cis rs9362426 0.943 rs1884320 chr6:88089160 C/T cg12350822 chr6:88032061 C6orf162;GJB7 -0.41 -4.45 -0.37 1.86e-5 Depressive episodes in bipolar disorder; TGCT trans rs6089829 0.926 rs7273917 chr20:61665975 G/A cg13615516 chr5:77269221 NA 0.69 8.53 0.61 4.28e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs6988636 0.534 rs62521775 chr8:124109949 A/G cg27053337 chr8:124217698 FAM83A 0.55 4.82 0.4 4.2e-6 Urinary uromodulin levels; TGCT cis rs11098499 0.865 rs28634456 chr4:120375778 A/G cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs1008375 0.966 rs10939755 chr4:17693755 T/C cg18681998 chr4:17616180 MED28 0.77 7.32 0.55 2.7e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs425277 1.000 rs262657 chr1:2088577 G/A cg24578937 chr1:2090814 PRKCZ 0.32 7.86 0.58 1.56e-12 Height; TGCT cis rs4722166 0.597 rs1554606 chr7:22768707 T/G cg13104385 chr7:22767384 IL6 0.23 4.99 0.41 2.03e-6 Lung cancer; TGCT cis rs6754311 0.517 rs1469995 chr2:136542559 G/A cg07169764 chr2:136633963 MCM6 0.89 7.81 0.57 2.05e-12 Mosquito bite size; TGCT cis rs881375 0.902 rs2900180 chr9:123706382 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.72 0.39 6.28e-6 Rheumatoid arthritis; TGCT cis rs911555 0.570 rs942862 chr14:104022124 G/C cg26031613 chr14:104095156 KLC1 0.6 5.4 0.44 3.22e-7 Intelligence (multi-trait analysis); TGCT cis rs4631830 0.869 rs4131357 chr10:51537292 C/A cg10326726 chr10:51549505 MSMB -0.25 -5.27 -0.43 5.73e-7 Prostate-specific antigen levels; TGCT cis rs10426930 0.621 rs10409229 chr19:5009545 C/T cg09001777 chr19:5851504 FUT3 0.24 4.6 0.38 1.03e-5 Monocyte percentage of white cells; TGCT cis rs751728 1.000 rs2296747 chr6:33744882 C/G cg13859433 chr6:33739653 LEMD2 -0.4 -7.16 -0.54 6.37e-11 Crohn's disease; TGCT cis rs853679 0.517 rs9468298 chr6:28122345 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7267979 1.000 rs2482919 chr20:25299756 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2204008 0.619 rs11178987 chr12:38201258 C/T cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Bladder cancer; TGCT cis rs10504229 0.683 rs16921819 chr8:58107936 G/T cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.694 rs7285041 chr22:41829149 G/T cg13695892 chr22:41940480 POLR3H 0.93 9.1 0.63 1.88e-15 Vitiligo; TGCT cis rs9341808 0.935 rs4706113 chr6:80839315 C/T cg08355045 chr6:80787529 NA 0.28 4.89 0.4 3.04e-6 Sitting height ratio; TGCT cis rs7178572 0.568 rs12912050 chr15:77689423 C/T cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs4253772 0.591 rs11705624 chr22:46685380 C/T cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs2204008 0.687 rs1733404 chr12:38123395 G/T cg26384229 chr12:38710491 ALG10B -0.85 -7.68 -0.57 4.21e-12 Bladder cancer; TGCT cis rs3733585 0.699 rs7694997 chr4:9947811 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.45 -0.5 2.22e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs858239 0.633 rs858300 chr7:23244631 A/G cg05407003 chr7:23246146 NA -0.29 -4.59 -0.38 1.07e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs3820068 0.705 rs57971278 chr1:15838604 G/A cg05660106 chr1:15850417 CASP9 1.13 13.41 0.77 6.7e-26 Systolic blood pressure; TGCT cis rs950169 0.920 rs17300048 chr15:84749477 C/T cg17173187 chr15:85201210 NMB 0.47 5.23 0.42 7.11e-7 Schizophrenia; TGCT cis rs10984561 0.881 rs73540236 chr9:122252550 T/C cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs11190604 0.767 rs10883483 chr10:102174244 T/C cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4319547 0.915 rs7314638 chr12:122983460 A/G cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.32 -0.43 4.71e-7 Body mass index; TGCT cis rs1976403 0.633 rs1697422 chr1:21821897 T/C cg17800788 chr1:21766015 NBPF3 0.25 4.77 0.39 4.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs637571 0.522 rs12792888 chr11:65761446 C/T cg17985854 chr11:65770987 BANF1;EIF1AD 0.21 4.51 0.38 1.46e-5 Eosinophil percentage of white cells; TGCT cis rs12200560 0.505 rs211174 chr6:97071120 C/T cg06623918 chr6:96969491 KIAA0776 0.59 5.02 0.41 1.76e-6 Coronary heart disease; TGCT cis rs7744392 0.557 rs9470007 chr6:35349739 C/T cg06087101 chr6:35551932 FKBP5 -0.61 -4.56 -0.38 1.21e-5 Cataracts in type 2 diabetes; TGCT cis rs10992471 0.603 rs10820968 chr9:95106443 A/G cg14631576 chr9:95140430 CENPP -0.31 -4.68 -0.39 7.5e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs11867934 0.724 rs4985746 chr17:17098213 G/A cg26176665 chr17:16994978 MPRIP 0.27 4.88 0.4 3.24e-6 Diabetic retinopathy; TGCT cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.835 rs1561230 chr2:100746642 C/T cg07810366 chr2:100720526 AFF3 0.47 7.78 0.57 2.45e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs13108904 0.846 rs9631805 chr4:1283035 T/C cg00684032 chr4:1343700 KIAA1530 -0.22 -4.47 -0.37 1.76e-5 Obesity-related traits; TGCT cis rs514406 0.929 rs562178 chr1:53319562 T/C cg16325326 chr1:53192061 ZYG11B 0.63 7.34 0.55 2.51e-11 Monocyte count; TGCT cis rs4689592 0.523 rs4256224 chr4:7074583 T/C cg02503808 chr4:7069936 GRPEL1 1.01 9.62 0.65 1.08e-16 Monocyte percentage of white cells; TGCT cis rs1534166 1.000 rs1534166 chr3:133537067 C/T cg16414030 chr3:133502952 NA -0.42 -4.96 -0.41 2.3e-6 Alcohol consumption (transferrin glycosylation); TGCT cis rs1075232 0.677 rs72714666 chr15:31492226 T/C cg01030201 chr15:31746330 NA -0.87 -4.63 -0.38 9.12e-6 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs2120019 0.935 rs34835684 chr15:75331805 T/G cg17294928 chr15:75287854 SCAMP5 -0.78 -6.12 -0.48 1.14e-8 Blood trace element (Zn levels); TGCT cis rs2439831 0.681 rs484029 chr15:43619560 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.63 0.51 9.35e-10 Lung cancer in ever smokers; TGCT cis rs9457247 0.515 rs1951459 chr6:167402536 G/A cg23791538 chr6:167370224 RNASET2 0.61 6.0 0.47 2.06e-8 Crohn's disease; TGCT cis rs9584850 0.794 rs9630321 chr13:99106979 C/G cg15168958 chr13:99100528 FARP1 -0.24 -4.53 -0.38 1.34e-5 Neuroticism; TGCT trans rs2727020 0.656 rs7925524 chr11:49437542 G/A cg15704280 chr7:45808275 SEPT13 -0.65 -6.64 -0.51 8.97e-10 Coronary artery disease; TGCT cis rs1577917 0.876 rs12201992 chr6:86618219 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs17376456 0.877 rs2290937 chr5:93356515 A/T cg25358565 chr5:93447407 FAM172A 1.01 8.01 0.58 6.99e-13 Diabetic retinopathy; TGCT cis rs7552404 0.889 rs380075 chr1:76106961 T/A cg10523679 chr1:76189770 ACADM -0.92 -10.1 -0.67 7.29e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9443645 0.901 rs1984195 chr6:79657391 G/A cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs6555052 chr5:224268 G/A cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs806215 1.000 rs806215 chr7:127237312 T/C cg25922125 chr7:127225783 GCC1 -0.57 -6.04 -0.48 1.64e-8 Type 2 diabetes; TGCT cis rs4478858 0.735 rs2889730 chr1:31827159 C/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.94 -0.41 2.46e-6 Alcohol dependence; TGCT cis rs12908161 0.959 rs1051168 chr15:85200520 G/T cg11189052 chr15:85197271 WDR73 0.75 6.14 0.48 1.04e-8 Schizophrenia; TGCT cis rs9486715 0.838 rs9320127 chr6:96865358 G/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs7100689 0.646 rs10736347 chr10:82134465 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs6570726 0.791 rs9403730 chr6:145907233 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs41307935 0.818 rs35576939 chr1:27274095 A/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs36051895 0.632 rs10115962 chr9:5140841 T/C cg02405213 chr9:5042618 JAK2 -0.74 -10.39 -0.68 1.4e-18 Pediatric autoimmune diseases; TGCT cis rs8177253 0.633 rs10935073 chr3:133439184 T/C cg16414030 chr3:133502952 NA -0.51 -7.13 -0.54 7.28e-11 Iron status biomarkers; TGCT cis rs1218582 0.710 rs4845687 chr1:154878911 A/G cg03351412 chr1:154909251 PMVK 0.54 5.02 0.41 1.72e-6 Prostate cancer; TGCT cis rs6089829 0.962 rs3746747 chr20:61667631 T/C cg08564027 chr20:61660810 NA 0.37 6.67 0.51 7.47e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs6570726 0.791 rs9497357 chr6:145912888 G/A cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.71e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs57221529 0.766 rs58015612 chr5:580665 A/T cg20362242 chr5:692897 TPPP 0.5 4.88 0.4 3.21e-6 Lung disease severity in cystic fibrosis; TGCT cis rs77741769 0.571 rs12580949 chr12:121298164 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.58e-5 Mean corpuscular volume; TGCT cis rs4332037 0.539 rs11772627 chr7:2109821 G/C cg25834613 chr7:1915315 MAD1L1 -0.52 -5.07 -0.41 1.41e-6 Bipolar disorder; TGCT cis rs11671005 0.693 rs11668821 chr19:58955813 G/A cg13877915 chr19:58951672 ZNF132 0.62 4.89 0.4 3.06e-6 Mean platelet volume; TGCT cis rs6424115 0.830 rs1130321 chr1:24200524 C/T cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs9611565 0.694 rs79008 chr22:41850500 C/T cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.52e-6 Vitiligo; TGCT cis rs9611565 0.512 rs5751145 chr22:42133552 C/T cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Vitiligo; TGCT cis rs7113874 0.569 rs1446463 chr11:8566329 G/A cg14521421 chr11:8862019 ST5 0.29 4.68 0.39 7.52e-6 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs2016266 0.819 rs4758965 chr12:53662735 C/T cg16917193 chr12:54089295 NA 0.64 5.35 0.43 4.04e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs2952156 1.000 rs2934971 chr17:37854507 G/T cg19468946 chr17:37922297 IKZF3 -0.18 -4.47 -0.37 1.72e-5 Asthma; TGCT cis rs2839186 0.770 rs2839171 chr21:47673247 C/T cg13732083 chr21:47605072 C21orf56 -0.35 -4.76 -0.39 5.38e-6 Testicular germ cell tumor; TGCT cis rs9291683 0.509 rs10939671 chr4:10050815 T/C cg11266682 chr4:10021025 SLC2A9 0.61 7.73 0.57 3.25e-12 Bone mineral density; TGCT cis rs7772486 0.790 rs4435956 chr6:146232403 G/C cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.899 rs6115213 chr20:25550372 G/A cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9916302 0.904 rs12452880 chr17:37591149 G/C cg07936489 chr17:37558343 FBXL20 -0.61 -4.81 -0.4 4.27e-6 Glomerular filtration rate (creatinine); TGCT cis rs2370759 1.000 rs16933225 chr10:32599464 C/T cg01819863 chr10:32635814 EPC1 0.96 9.09 0.63 1.96e-15 Sexual dysfunction (female); TGCT cis rs7267979 0.816 rs8115257 chr20:25207931 A/G cg03522245 chr20:25566470 NINL 0.53 5.3 0.43 5.05e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 0.765 rs1974435 chr17:61994096 G/A cg11494091 chr17:61959527 GH2 -0.59 -15.93 -0.82 8.56e-32 Prudent dietary pattern; TGCT cis rs6840360 1.000 rs6841783 chr4:152598876 C/G cg17479576 chr4:152424074 FAM160A1 -0.5 -5.4 -0.44 3.26e-7 Intelligence (multi-trait analysis); TGCT cis rs698813 0.637 rs7579841 chr2:44498887 T/A cg00619915 chr2:44497795 NA -0.24 -5.52 -0.44 1.91e-7 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs78487399 0.710 rs80147536 chr2:43698028 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.52 -0.38 1.42e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg16590910 chr6:42928470 GNMT -0.49 -4.52 -0.38 1.4e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs904251 0.698 rs2646926 chr6:37424988 G/A cg25019722 chr6:37503610 NA -0.4 -4.75 -0.39 5.48e-6 Cognitive performance; TGCT cis rs61935443 0.720 rs10859784 chr12:95288926 G/A cg21533806 chr12:95267307 NA 0.55 4.83 0.4 3.88e-6 Schizophrenia; TGCT cis rs7523273 0.526 rs12132968 chr1:207884292 T/C cg22525895 chr1:207977042 MIR29B2 0.35 5.73 0.46 7.22e-8 Schizophrenia; TGCT cis rs10791323 0.582 rs2851120 chr11:133708065 A/G cg03690763 chr11:133734501 NA -0.31 -4.88 -0.4 3.18e-6 Childhood ear infection; TGCT trans rs6951245 0.554 rs79367977 chr7:1152657 G/A cg13565492 chr6:43139072 SRF -0.81 -7.71 -0.57 3.45e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs362272 0.545 rs2749782 chr4:3339761 A/G cg06533319 chr4:3265114 C4orf44 -0.26 -5.38 -0.44 3.51e-7 Serum sulfate level; TGCT cis rs9682041 1.000 rs15709 chr3:170110529 T/A cg07589077 chr3:170072950 NA 0.3 4.54 0.38 1.3e-5 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs9581857 0.579 rs76657892 chr13:27997604 A/G cg22138327 chr13:27999177 GTF3A 0.81 5.74 0.46 6.97e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT trans rs916888 0.779 rs199528 chr17:44843136 C/T cg07870213 chr5:140052090 DND1 0.61 7.51 0.56 9.93e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs877282 0.583 rs12358255 chr10:828626 C/T cg22713356 chr15:30763199 NA 0.89 6.71 0.52 6.26e-10 Uric acid levels; TGCT cis rs9814567 0.806 rs7648616 chr3:134318074 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.54 -4.78 -0.39 4.9100000000000004e-06 Prudent dietary pattern; TGCT cis rs9549367 0.713 rs3024776 chr13:113827075 A/G cg09473364 chr13:112927190 NA 0.3 4.53 0.38 1.35e-5 Platelet distribution width; TGCT cis rs4746818 1.000 rs4746817 chr10:70882515 T/C cg11621586 chr10:70884670 VPS26A 1.12 7.84 0.58 1.73e-12 Left atrial antero-posterior diameter; TGCT cis rs939574 1.000 rs45488900 chr2:220116509 G/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.05 6.46 0.5 2.12e-9 Platelet distribution width; TGCT cis rs7726839 0.540 rs72703092 chr5:599269 G/A cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT trans rs1005277 0.579 rs2474586 chr10:38418882 T/C cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs72627509 0.680 rs12648788 chr4:57717475 A/T cg26694713 chr4:57773883 REST 0.76 6.03 0.48 1.75e-8 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs651907 0.557 rs62284198 chr3:101474699 G/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.68 0.39 7.44e-6 Colorectal cancer; TGCT cis rs739401 0.611 rs417957 chr11:3046231 A/G cg05729581 chr11:3078854 CARS -0.56 -5.22 -0.42 7.36e-7 Longevity; TGCT cis rs2803122 0.502 rs1329731 chr9:19234908 C/T cg13469590 chr9:19229767 NA -0.48 -4.51 -0.38 1.48e-5 Pulse pressure; TGCT cis rs1395 0.634 rs72817542 chr2:27526681 C/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.95 0.58 1e-12 Blood metabolite levels; TGCT cis rs55882075 0.967 rs62404346 chr5:179141391 A/C cg14593053 chr5:179126677 CANX 0.45 4.76 0.39 5.28e-6 Monocyte percentage of white cells; TGCT trans rs208520 1.000 rs72884033 chr6:66995747 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.84 7.59 0.56 6.69e-12 Exhaled nitric oxide output; TGCT cis rs735396 0.965 rs2257962 chr12:121445808 T/C cg02403541 chr12:121454288 C12orf43 0.66 6.38 0.5 3.2e-9 N-glycan levels; TGCT cis rs3845702 0.877 rs12693216 chr2:180839793 T/A cg01881094 chr2:180872142 CWC22 -0.68 -6.06 -0.48 1.51e-8 Schizophrenia; TGCT cis rs7267979 0.966 rs6037097 chr20:25347221 C/T cg14121845 chr20:25566513 NINL 0.5 5.3 0.43 5.23e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs6951245 1.000 rs75488469 chr7:1102122 A/G cg27454412 chr7:1067447 C7orf50 0.59 4.63 0.38 8.92e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1371867 0.846 rs1788206 chr8:101306966 A/G cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs2204008 0.807 rs11182461 chr12:38539288 T/C cg26384229 chr12:38710491 ALG10B 0.89 8.13 0.59 3.76e-13 Bladder cancer; TGCT cis rs10927875 0.518 rs1763597 chr1:16343297 C/T cg22431228 chr1:16359049 CLCNKA -0.29 -6.07 -0.48 1.42e-8 Dilated cardiomyopathy; TGCT cis rs3087591 1.000 rs2051507 chr17:29700101 A/G cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.28 -0.55 3.31e-11 Hip circumference; TGCT cis rs6450176 0.909 rs12659966 chr5:53292892 C/G ch.5.1024479R chr5:53302184 ARL15 0.49 4.67 0.39 7.77e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs801193 1.000 rs2659915 chr7:66153101 A/G cg00343986 chr7:65444356 GUSB 0.2 4.65 0.39 8.47e-6 Aortic root size; TGCT cis rs9926296 0.581 rs12598477 chr16:89902482 T/C cg08627397 chr16:89984028 MC1R -0.34 -5.43 -0.44 2.79e-7 Vitiligo; TGCT cis rs2290416 0.688 rs62522171 chr8:144690832 C/A cg16316162 chr8:144660157 NAPRT1 0.68 4.48 0.37 1.71e-5 Attention deficit hyperactivity disorder; TGCT cis rs7666738 0.830 rs6827516 chr4:98971740 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg10150615 chr22:24372951 LOC391322 -0.96 -11.9 -0.73 2.98e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs422249 0.547 rs174533 chr11:61549025 G/A cg19610905 chr11:61596333 FADS2 -1.05 -10.42 -0.68 1.18e-18 Trans fatty acid levels; TGCT cis rs12579753 0.917 rs7138895 chr12:82203280 T/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs7772486 0.875 rs2777477 chr6:146305491 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.92 0.4 2.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7824557 0.602 rs7815463 chr8:11210983 A/G cg21775007 chr8:11205619 TDH 0.73 7.03 0.53 1.23e-10 Retinal vascular caliber; TGCT cis rs77633900 0.614 rs2439989 chr15:76883862 G/C cg21673338 chr15:77095150 SCAPER -0.52 -4.83 -0.4 3.88e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg08859206 chr1:53392774 SCP2 -0.47 -7.31 -0.55 2.92e-11 Monocyte count; TGCT cis rs2153535 0.580 rs1928184 chr6:8532108 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs67311347 1.000 rs11539046 chr3:40503809 G/A cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs4819052 0.851 rs12626188 chr21:46669258 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 6.95 0.53 1.86e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28374715 0.532 rs11854820 chr15:41676526 G/A cg18705301 chr15:41695430 NDUFAF1 -0.93 -16.21 -0.82 2.08e-32 Ulcerative colitis; TGCT cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs12541335 0.639 rs11135995 chr8:22200148 C/T cg09517075 chr8:22133004 PIWIL2 -0.24 -4.92 -0.4 2.72e-6 Hypertriglyceridemia; TGCT cis rs597480 0.892 rs680498 chr11:85447611 C/T cg11817631 chr11:85522609 SYTL2 0.51 5.09 0.42 1.29e-6 Drug-induced liver injury (nonsteroidal anti-inflammatory drugs); TGCT cis rs9302065 0.681 rs9524903 chr13:95963565 A/G cg24476569 chr13:95954382 ABCC4 -0.45 -6.44 -0.5 2.43e-9 Blood metabolite levels; TGCT cis rs4665809 1.000 rs6546726 chr2:26275116 A/G cg27170947 chr2:26402098 FAM59B -0.4 -4.55 -0.38 1.25e-5 Gut microbiome composition (summer); TGCT cis rs6952809 0.532 rs6952152 chr7:2440912 G/A cg23289794 chr7:2394357 EIF3B -0.84 -7.21 -0.54 4.72e-11 Multiple sclerosis; TGCT cis rs2439831 0.681 rs28594657 chr15:43588888 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.92 5.27 0.43 5.83e-7 Lung cancer in ever smokers; TGCT cis rs4631830 0.863 rs2926494 chr10:51517356 T/C cg10326726 chr10:51549505 MSMB -0.25 -4.99 -0.41 2.01e-6 Prostate-specific antigen levels; TGCT cis rs4924935 1.000 rs35341640 chr17:18818228 G/A cg26378065 chr17:18585709 ZNF286B -0.56 -4.72 -0.39 6.38e-6 Pancreatic cancer; TGCT cis rs12477438 0.520 rs6542865 chr2:99764521 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs79349575 0.783 rs55771415 chr17:46999937 C/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs12681287 0.673 rs4464946 chr8:87326259 G/A cg27223183 chr8:87520930 FAM82B -0.92 -6.97 -0.53 1.7e-10 Caudate activity during reward; TGCT cis rs1268083 0.546 rs9398785 chr6:126057748 A/G cg05901451 chr6:126070800 HEY2 -0.78 -7.25 -0.55 4e-11 Migraine; TGCT cis rs7804356 1.000 rs12532395 chr7:26841702 G/A cg03456212 chr7:26904342 SKAP2 -0.61 -4.7 -0.39 6.82e-6 Type 1 diabetes; TGCT cis rs1552244 0.882 rs13100734 chr3:10022878 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.85 5.54 0.45 1.71e-7 Alzheimer's disease; TGCT cis rs35306767 0.903 rs61830933 chr10:934195 G/A cg20503657 chr10:835505 NA 0.8 11.88 0.73 3.41e-22 Eosinophil percentage of granulocytes; TGCT cis rs13191362 1.000 rs35383933 chr6:163002869 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3771570 1.000 rs3771570 chr2:242382864 C/T cg21155796 chr2:242212141 HDLBP 0.93 6.6 0.51 1.08e-9 Prostate cancer; TGCT cis rs908922 0.676 rs11581947 chr1:152482587 G/A cg20991723 chr1:152506922 NA 0.47 6.65 0.51 8.33e-10 Hair morphology; TGCT cis rs4730250 0.707 rs257373 chr7:106798290 G/A cg02696742 chr7:106810147 HBP1 -0.73 -6.04 -0.48 1.63e-8 Osteoarthritis; TGCT cis rs6722750 1.000 rs6722750 chr2:64381259 T/G cg22352474 chr2:64371530 PELI1 0.58 4.97 0.41 2.14e-6 Neuroticism; TGCT cis rs13272623 0.502 rs268627 chr8:71561041 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.61 -5.12 -0.42 1.12e-6 IgG glycosylation; TGCT cis rs739496 0.579 rs12322899 chr12:112288202 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs637571 0.522 rs679581 chr11:65746653 A/G cg02427764 chr11:65769310 BANF1;EIF1AD 0.67 6.58 0.51 1.18e-9 Eosinophil percentage of white cells; TGCT cis rs9467773 0.967 rs7753565 chr6:26560012 A/G cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs6938 0.534 rs4886636 chr15:75196176 G/A cg10253484 chr15:75165896 SCAMP2 -0.55 -5.1 -0.42 1.22e-6 Breast cancer; TGCT cis rs2842992 0.789 rs10945635 chr6:160214487 C/A cg11366901 chr6:160182831 ACAT2 1.06 7.17 0.54 5.89e-11 Age-related macular degeneration (geographic atrophy); TGCT cis rs7584330 0.868 rs13408361 chr2:238382899 A/G cg16989719 chr2:238392110 NA -0.26 -4.48 -0.37 1.7e-5 Prostate cancer; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg12419862 chr22:24373484 LOC391322 -0.81 -8.64 -0.61 2.33e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs611744 0.901 rs2348801 chr8:109167337 C/T cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs1799949 1.000 rs4793212 chr17:41302750 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs7208859 0.673 rs73263776 chr17:29211331 G/C cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs394563 0.622 rs237024 chr6:149721965 T/C cg03678062 chr6:149772716 ZC3H12D -0.38 -4.82 -0.4 4.12e-6 Dupuytren's disease; TGCT cis rs2153535 0.580 rs9328486 chr6:8528008 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs12477438 1.000 rs6732980 chr2:99921613 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.78 -0.62 1.12e-14 Chronic sinus infection; TGCT cis rs9611565 0.512 rs1983576 chr22:42166486 G/A cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs832540 0.656 rs6862118 chr5:56106474 G/A cg24531977 chr5:56204891 C5orf35 -0.55 -5.47 -0.44 2.37e-7 Coronary artery disease; TGCT cis rs13108904 0.846 rs9631804 chr4:1283032 A/T cg00684032 chr4:1343700 KIAA1530 -0.22 -4.47 -0.37 1.76e-5 Obesity-related traits; TGCT cis rs9611565 0.659 rs12484175 chr22:41953739 A/C cg17554472 chr22:41940697 POLR3H -0.5 -5.37 -0.43 3.72e-7 Vitiligo; TGCT cis rs13326165 0.511 rs1011063 chr3:52506848 A/G cg07884673 chr3:53033167 SFMBT1 0.39 4.87 0.4 3.39e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg15687855 chr3:44754131 ZNF502 -0.48 -5.93 -0.47 2.83e-8 Depressive symptoms; TGCT cis rs6582630 0.519 rs11181998 chr12:38439970 C/A cg26384229 chr12:38710491 ALG10B 0.84 7.7 0.57 3.77e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs926938 0.520 rs4140445 chr1:115291978 T/C cg12756093 chr1:115239321 AMPD1 -0.41 -4.93 -0.4 2.62e-6 Autism; TGCT cis rs9581857 0.556 rs9579085 chr13:28041039 G/A cg22138327 chr13:27999177 GTF3A 0.73 5.7 0.46 8.09e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs73198271 0.653 rs10099808 chr8:8659873 A/G cg06671706 chr8:8559999 CLDN23 0.36 4.62 0.38 9.5e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs832540 0.603 rs6870175 chr5:56093371 A/G cg12311346 chr5:56204834 C5orf35 -0.49 -5.13 -0.42 1.08e-6 Coronary artery disease; TGCT cis rs1008375 1.000 rs1558377 chr4:17650758 A/G cg10189774 chr4:17578691 LAP3 0.6 5.29 0.43 5.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1371867 0.875 rs1660319 chr8:101337530 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.73 -0.39 6.08e-6 Atrioventricular conduction; TGCT cis rs1577917 0.876 rs11752223 chr6:86573394 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.47 -0.44 2.33e-7 Response to antipsychotic treatment; TGCT cis rs2299587 0.521 rs3739406 chr8:17739538 T/C cg01800426 chr8:17659068 MTUS1 -0.56 -4.99 -0.41 1.97e-6 Economic and political preferences; TGCT cis rs35146811 0.735 rs1727133 chr7:99812870 C/T cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs3087591 0.960 rs34941185 chr17:29425587 G/A cg24425628 chr17:29625626 OMG;NF1 0.47 7.16 0.54 6.19e-11 Hip circumference; TGCT cis rs12049351 0.774 rs12138176 chr1:229657902 G/A cg12130225 chr1:229698885 NA 0.38 4.59 0.38 1.09e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7599312 0.534 rs6751692 chr2:213408120 C/T cg16329650 chr2:213403929 ERBB4 1.08 16.09 0.82 3.86e-32 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7772486 0.754 rs6921073 chr6:146144377 G/A cg05347473 chr6:146136440 FBXO30 0.5 4.72 0.39 6.35e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs1005277 0.579 rs2474572 chr10:38385316 A/G cg27523141 chr10:43048294 ZNF37B 0.71 8.31 0.6 1.4e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2302464 1.000 rs11944132 chr4:15725914 C/T cg18497811 chr4:14860861 NA -0.48 -4.47 -0.37 1.76e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs3772130 0.962 rs6784571 chr3:121539991 C/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs17122693 0.710 rs77598393 chr14:51159342 T/G cg04730355 chr14:51134070 SAV1 1.22 9.45 0.65 2.75e-16 Cognitive performance; TGCT cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs10504229 0.679 rs12679941 chr8:58051812 G/T cg08219700 chr8:58056026 NA 0.29 4.45 0.37 1.91e-5 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.697 rs45557936 chr20:30226690 G/A cg18721089 chr20:30220636 NA -0.53 -5.43 -0.44 2.86e-7 Mean corpuscular hemoglobin; TGCT cis rs2180341 0.843 rs4895821 chr6:127572761 T/A cg24812749 chr6:127587940 RNF146 0.93 7.35 0.55 2.36e-11 Breast cancer; TGCT cis rs909002 0.811 rs11575883 chr1:32085485 G/A cg11573219 chr1:32083031 HCRTR1 -0.49 -6.39 -0.5 3.06e-9 Intelligence (multi-trait analysis); TGCT cis rs1158570 0.835 rs6470816 chr8:131349715 C/T cg16277922 chr8:131349729 ASAP1 -0.6 -10.42 -0.68 1.19e-18 Platelet count; TGCT cis rs28595532 1.000 rs56225646 chr4:119651217 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs26868 0.690 rs26835 chr16:2237549 C/T cg02248941 chr16:2239361 CASKIN1 0.17 4.58 0.38 1.1e-5 Height; TGCT cis rs35000415 0.745 rs117944677 chr7:128698185 A/T cg06242719 chr7:129414860 MIR183;MIR96 -0.34 -4.67 -0.39 7.58e-6 Systemic lupus erythematosus; TGCT trans rs561341 1.000 rs72823789 chr17:30284084 G/A cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs3733585 0.674 rs7375643 chr4:9955239 A/G cg11266682 chr4:10021025 SLC2A9 -0.62 -8.62 -0.61 2.56e-14 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1018836 0.923 rs13268594 chr8:91588545 G/T cg16814680 chr8:91681699 NA -0.85 -8.84 -0.62 7.73e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs28595532 0.764 rs56359736 chr4:119769689 G/A cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs11971779 0.941 rs74299967 chr7:139043769 G/T cg07862535 chr7:139043722 LUC7L2 0.79 5.85 0.46 4.16e-8 Diisocyanate-induced asthma; TGCT cis rs67311347 0.956 rs4974029 chr3:40521318 C/G cg17264618 chr3:40429014 ENTPD3 0.33 4.75 0.39 5.53e-6 Renal cell carcinoma; TGCT cis rs6076065 0.548 rs6048740 chr20:23325047 G/A cg11657817 chr20:23433608 CST11 0.28 5.03 0.41 1.67e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs782590 0.935 rs782606 chr2:55886602 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.74 0.52 5.25e-10 Metabolic syndrome; TGCT cis rs210138 1.000 rs210144 chr6:33547430 G/A cg24505687 chr6:33548425 BAK1 0.53 6.11 0.48 1.16e-8 Testicular germ cell tumor; TGCT cis rs7103648 0.838 rs2293576 chr11:47434986 A/G cg20307385 chr11:47447363 PSMC3 -0.98 -11.23 -0.71 1.31e-20 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs9611565 0.546 rs739134 chr22:42089623 T/C cg17554472 chr22:41940697 POLR3H 0.5 5.36 0.43 3.92e-7 Vitiligo; TGCT cis rs7511006 1.000 rs7511006 chr22:50676259 T/C cg16473166 chr22:50639996 SELO 0.61 5.99 0.47 2.15e-8 Obesity-related traits; TGCT cis rs904251 0.523 rs9349039 chr6:37480392 A/G cg25019722 chr6:37503610 NA -0.54 -7.82 -0.57 1.92e-12 Cognitive performance; TGCT cis rs13256369 0.950 rs1522839 chr8:8580453 C/T cg17143192 chr8:8559678 CLDN23 0.63 5.6 0.45 1.34e-7 Obesity-related traits; TGCT cis rs17221829 0.733 rs11018681 chr11:89364443 C/T cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs1580019 0.885 rs1610141 chr7:32498435 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.85 7.95 0.58 9.92e-13 Cognitive ability; TGCT cis rs763014 0.932 rs2384972 chr16:674424 G/A cg07343612 chr16:622815 PIGQ -0.42 -8.4 -0.6 8.47e-14 Height; TGCT trans rs941408 1.000 rs941406 chr19:2803623 A/G cg22153745 chr1:153894579 GATAD2B -0.77 -7.96 -0.58 9.1e-13 Total cholesterol levels; TGCT cis rs9985766 0.958 rs10022936 chr4:150988778 T/C cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs72781680 0.898 rs72780125 chr2:24000145 T/C cg08917208 chr2:24149416 ATAD2B 0.93 5.84 0.46 4.22e-8 Lymphocyte counts; TGCT cis rs10504229 0.683 rs56408763 chr8:58137276 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs9677476 1.000 rs9677476 chr2:232126290 C/T cg07929768 chr2:232055508 NA -0.3 -4.48 -0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs9916302 0.904 rs1966916 chr17:37425238 T/G cg15445000 chr17:37608096 MED1 0.32 4.69 0.39 7.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs4654899 0.758 rs6689852 chr1:21341051 T/C cg01072550 chr1:21505969 NA -0.55 -8.93 -0.63 4.73e-15 Superior frontal gyrus grey matter volume; TGCT cis rs1799949 0.965 rs33988650 chr17:41287880 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs597539 0.616 rs473997 chr11:68639481 C/T cg21963583 chr11:68658836 MRPL21 0.36 6.1 0.48 1.25e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs60871478 0.636 rs12532761 chr7:905229 C/T cg15782153 chr7:917662 C7orf20 0.57 5.12 0.42 1.14e-6 Cerebrospinal P-tau181p levels; TGCT cis rs7586879 0.575 rs6721750 chr2:25128719 A/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs7772486 0.817 rs12198065 chr6:146385286 G/C cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2549003 1.000 rs2548997 chr5:131835395 C/T cg00255919 chr5:131827918 IRF1 -0.22 -5.3 -0.43 5.07e-7 Asthma (sex interaction); TGCT cis rs4499344 0.730 rs406470 chr19:33104472 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.63 0.61 2.53e-14 Mean platelet volume; TGCT cis rs11105298 0.891 rs10858852 chr12:89833338 T/C cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1008375 1.000 rs2058338 chr4:17678600 A/G cg10189774 chr4:17578691 LAP3 -0.64 -6.07 -0.48 1.44e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2153535 0.580 rs1414350 chr6:8472331 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs35883536 1.000 rs2297716 chr1:101092526 G/C cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.19e-5 Monocyte count; TGCT cis rs769267 0.825 rs1469713 chr19:19528806 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.51 0.5 1.71e-9 Tonsillectomy; TGCT cis rs77861329 0.920 rs9860982 chr3:52096432 T/C cg08692210 chr3:52188851 WDR51A 0.96 4.5 0.37 1.54e-5 Macrophage inflammatory protein 1b levels; TGCT cis rs9911578 0.900 rs7214335 chr17:57158840 G/A cg05425664 chr17:57184151 TRIM37 -0.64 -6.28 -0.49 5.3300000000000004e-09 Intelligence (multi-trait analysis); TGCT trans rs10506458 1.000 rs73128794 chr12:63445313 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.62 -0.56 5.8e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs6714710 0.603 rs2305143 chr2:98413781 C/T cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs8017423 0.967 rs2151748 chr14:90694897 G/C cg04374321 chr14:90722782 PSMC1 0.78 8.11 0.59 4.21e-13 Mortality in heart failure; TGCT cis rs763121 1.000 rs1946990 chr22:38912771 C/T cg06022373 chr22:39101656 GTPBP1 -0.77 -7.79 -0.57 2.26e-12 Menopause (age at onset); TGCT cis rs2468186 0.554 rs2450066 chr8:120096807 A/C cg02248809 chr8:120845432 TAF2 -0.45 -4.83 -0.4 3.99e-6 Osteoprotegerin levels; TGCT cis rs6570726 0.791 rs4332001 chr6:145934841 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.49 -0.37 1.59e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs826838 0.967 rs1684411 chr12:39128494 C/T cg13010199 chr12:38710504 ALG10B -0.59 -4.66 -0.39 8.16e-6 Heart rate; TGCT cis rs2637266 1.000 rs2395394 chr10:78360679 G/C cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs78545713 0.881 rs74608402 chr6:26240474 C/T cg12260798 chr6:26240519 HIST1H4F -0.64 -4.65 -0.39 8.25e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs950169 0.810 rs62029594 chr15:84955252 T/C cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs9926296 0.605 rs7205053 chr16:89856763 G/C cg04287289 chr16:89883240 FANCA 0.94 11.98 0.73 1.9e-22 Vitiligo; TGCT cis rs3772130 0.962 rs4311252 chr3:121514161 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.53 4.83 0.4 3.94e-6 Cognitive performance; TGCT cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg13393036 chr8:95962371 TP53INP1 -0.65 -8.97 -0.63 3.91e-15 Type 2 diabetes; TGCT cis rs9898058 0.545 rs75764946 chr17:47782865 G/T cg10517230 chr17:48661425 CACNA1G 0.47 4.5 0.37 1.53e-5 Milk allergy; TGCT cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.24e-9 Blood metabolite levels; TGCT cis rs2549003 1.000 rs2549003 chr5:131829297 A/G cg02551604 chr5:131831745 NA -0.9 -12.28 -0.74 3.61e-23 Asthma (sex interaction); TGCT cis rs28595532 0.920 rs114414928 chr4:119728188 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs694739 1.000 rs646153 chr11:64089588 C/T cg02228329 chr11:64053129 BAD;GPR137 0.8 7.9 0.58 1.26e-12 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9534288 0.797 rs7990095 chr13:46587262 G/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs7647973 0.506 rs11920251 chr3:49356671 C/T cg03060546 chr3:49711283 APEH 0.66 6.51 0.5 1.71e-9 Menarche (age at onset); TGCT cis rs13191362 0.935 rs7763118 chr6:162954720 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.65 5.18 0.42 8.81e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6125597 0.967 rs6063378 chr20:47866411 C/T cg11220565 chr20:47934802 NA -0.3 -4.6 -0.38 1.02e-5 Intelligence (multi-trait analysis); TGCT cis rs12615966 0.929 rs9941698 chr2:105384717 G/A cg16465502 chr2:105461796 NA 0.78 5.03 0.41 1.66e-6 Pancreatic cancer; TGCT cis rs7412746 0.658 rs72704685 chr1:150897687 C/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs3772130 0.923 rs13090798 chr3:121482768 C/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs6089584 0.854 rs2380146 chr20:60632233 C/T cg13665807 chr20:60559372 TAF4 -0.51 -5.25 -0.43 6.34e-7 Body mass index; TGCT cis rs11098499 0.954 rs9993199 chr4:120392873 A/G cg09307838 chr4:120376055 NA -0.69 -6.57 -0.51 1.22e-9 Corneal astigmatism; TGCT cis rs10782582 0.609 rs11588643 chr1:76255613 A/G cg03433033 chr1:76189801 ACADM -0.5 -4.95 -0.41 2.39e-6 Daytime sleep phenotypes; TGCT cis rs4246949 0.597 rs4625397 chr10:125519383 A/G cg12769705 chr10:125521557 CPXM2 -0.43 -4.53 -0.38 1.36e-5 Ulcerative colitis; TGCT cis rs1056107 0.931 rs10118422 chr9:114998396 A/G cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs10504229 0.953 rs66509078 chr8:58174734 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7086627 0.515 rs7077373 chr10:82211615 C/T cg00277334 chr10:82204260 NA -0.54 -8.46 -0.61 6.23e-14 Post bronchodilator FEV1; TGCT cis rs4595586 0.545 rs2388179 chr12:39364036 T/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT trans rs1496653 0.602 rs35156003 chr3:23425738 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs921968 0.612 rs4674323 chr2:219517088 T/C cg02176678 chr2:219576539 TTLL4 0.38 5.47 0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7226408 0.857 rs72887072 chr18:34499453 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs13328042 chr4:99055406 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.825 rs28705226 chr5:93233135 T/C cg25358565 chr5:93447407 FAM172A 1.01 8.13 0.59 3.77e-13 Diabetic retinopathy; TGCT cis rs6088580 0.634 rs1205344 chr20:32918298 G/A cg08999081 chr20:33150536 PIGU -0.25 -4.99 -0.41 2e-6 Glomerular filtration rate (creatinine); TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg07594247 chr2:113993304 PAX8;LOC440839;LOC654433 0.51 5.51 0.44 2.02e-7 Lymphocyte counts; TGCT cis rs3087591 0.922 rs2905879 chr17:29545431 T/A cg24425628 chr17:29625626 OMG;NF1 0.46 7.17 0.54 6.02e-11 Hip circumference; TGCT cis rs4242434 0.819 rs1059592 chr8:22477778 G/A cg03733263 chr8:22462867 KIAA1967 1.06 16.11 0.82 3.45e-32 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg19723775 chr5:179050963 HNRNPH1 0.48 4.58 0.38 1.13e-5 Lung cancer; TGCT cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs651907 0.535 rs13065944 chr3:101473088 G/A cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.78 -0.52 4.35e-10 Colorectal cancer; TGCT cis rs10504229 1.000 rs67188507 chr8:58187492 A/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.589 rs16922779 chr9:5200127 G/A cg02405213 chr9:5042618 JAK2 -0.75 -9.79 -0.66 4.03e-17 Pediatric autoimmune diseases; TGCT cis rs514406 0.861 rs10888755 chr1:53240829 A/G cg08859206 chr1:53392774 SCP2 0.41 6.25 0.49 6.12e-9 Monocyte count; TGCT cis rs3892630 0.588 rs12610342 chr19:33250690 C/T cg22980127 chr19:33182716 NUDT19 0.75 6.12 0.48 1.14e-8 Red blood cell traits; TGCT cis rs2013441 1.000 rs17686839 chr17:20039171 A/G cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs2115630 1.000 rs7183401 chr15:85371944 G/T cg11189052 chr15:85197271 WDR73 -0.67 -6.53 -0.51 1.56e-9 P wave terminal force; TGCT cis rs7647973 1.000 rs13322887 chr3:49555583 G/A cg07636037 chr3:49044803 WDR6 -0.65 -5.35 -0.43 4.01e-7 Menarche (age at onset); TGCT cis rs13064447 0.845 rs11128610 chr3:12761123 G/T cg20675869 chr3:12750130 NA -0.2 -4.99 -0.41 2.03e-6 Major depression and alcohol dependence; TGCT cis rs2456568 0.802 rs1506656 chr11:93639813 G/A cg17595323 chr11:93583763 C11orf90 -0.46 -6.23 -0.49 6.52e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs886126 0.650 rs4766566 chr12:111706877 C/T cg10833066 chr12:111807467 FAM109A 0.37 6.55 0.51 1.37e-9 Coronary heart disease; TGCT cis rs17473412 1.000 rs17473412 chr5:122697431 C/T cg15125798 chr5:122621645 NA -0.57 -5.0 -0.41 1.89e-6 Total body bone mineral density; TGCT cis rs904251 0.523 rs2797794 chr6:37480604 T/C cg01843034 chr6:37503916 NA -0.55 -7.33 -0.55 2.54e-11 Cognitive performance; TGCT cis rs7552404 0.696 rs10518521 chr1:76461214 G/A cg03433033 chr1:76189801 ACADM 0.73 6.74 0.52 5.45e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9318086 0.935 rs9553083 chr13:24441525 C/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.68 -6.77 -0.52 4.61e-10 Myopia (pathological); TGCT cis rs9993613 0.875 rs16848284 chr4:73476901 T/C cg15102770 chr4:73434591 ADAMTS3 0.54 4.96 0.41 2.26e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs2204008 0.701 rs3898237 chr12:38219714 A/G cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs9926296 0.533 rs10852623 chr16:89865242 T/C cg27121462 chr16:89883253 FANCA 0.79 8.71 0.62 1.62e-14 Vitiligo; TGCT cis rs9913156 0.748 rs55959711 chr17:4562581 C/A cg19197139 chr17:4613644 ARRB2 0.86 7.9 0.58 1.32e-12 Lymphocyte counts; TGCT cis rs1183201 0.505 rs1165201 chr6:25874823 A/C cg12310025 chr6:25882481 NA -1.02 -11.72 -0.73 8.08e-22 Uric acid levels; TGCT cis rs9894429 0.752 rs6565610 chr17:79592652 A/G cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs801193 1.000 rs7783924 chr7:66209057 A/C cg00343986 chr7:65444356 GUSB 0.24 5.25 0.43 6.3e-7 Aortic root size; TGCT cis rs477895 0.838 rs11607007 chr11:64007976 C/T cg04317338 chr11:64019027 PLCB3 0.82 7.02 0.53 1.3e-10 Mean platelet volume; TGCT cis rs151997 0.853 rs6882235 chr5:50260139 T/C cg06027927 chr5:50259733 NA 0.57 5.94 0.47 2.72e-8 Callous-unemotional behaviour; TGCT cis rs7772486 0.790 rs2485632 chr6:146193228 A/G cg23711669 chr6:146136114 FBXO30 0.95 10.8 0.7 1.44e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs4689388 0.926 rs5018647 chr4:6292799 A/C cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs11191270 0.554 rs11191265 chr10:104102118 G/A cg15320455 chr10:103880129 LDB1 0.86 5.39 0.44 3.48e-7 Intelligence (multi-trait analysis); TGCT cis rs7178572 0.568 rs4886515 chr15:77686886 G/A cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg12419862 chr22:24373484 LOC391322 -0.75 -6.97 -0.53 1.66e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg18867708 chr6:26865862 GUSBL1 -0.38 -5.03 -0.41 1.65e-6 Autism spectrum disorder or schizophrenia; TGCT trans rs72634030 0.702 rs3026105 chr17:5281758 C/T cg08933409 chr10:42672859 NA 0.88 6.65 0.51 8.16e-10 Rheumatoid arthritis; TGCT cis rs10504229 1.000 rs77120900 chr8:58170368 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.841 rs114465037 chr4:119778165 A/G cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg21672276 chr3:44754072 ZNF502 -0.49 -5.68 -0.45 8.97e-8 Depressive symptoms; TGCT cis rs514406 0.825 rs6588441 chr1:53223494 G/A cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.42e-13 Monocyte count; TGCT cis rs250677 0.522 rs4705301 chr5:148354902 C/G cg18129178 chr5:148520854 ABLIM3 -0.35 -4.5 -0.37 1.53e-5 Breast cancer; TGCT cis rs2204008 0.617 rs11831608 chr12:38210687 C/T cg26384229 chr12:38710491 ALG10B -0.6 -5.2 -0.42 7.91e-7 Bladder cancer; TGCT cis rs17681684 0.565 rs12150149 chr17:9764039 A/C cg15743799 chr17:9805578 RCVRN 0.25 5.41 0.44 3.16e-7 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs3749237 1.000 rs3749237 chr3:49770032 C/T cg07636037 chr3:49044803 WDR6 0.64 5.63 0.45 1.13e-7 Resting heart rate; TGCT cis rs6543140 0.964 rs62154972 chr2:103048738 G/A cg09003973 chr2:102972529 NA 0.6 4.98 0.41 2.12e-6 Blood protein levels; TGCT cis rs7267979 1.000 rs2424712 chr20:25416942 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7193541 0.640 rs4072222 chr16:74706736 A/C cg01733217 chr16:74700730 RFWD3 0.98 12.91 0.76 1.1e-24 Multiple myeloma; TGCT cis rs66573146 1.000 rs6812391 chr4:6963893 G/A cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1057239 0.739 rs1014554 chr1:175133626 A/G cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Diastolic blood pressure; TGCT cis rs13242816 1.000 rs35595472 chr7:116122306 G/A cg16553024 chr7:116138462 CAV2 -0.44 -4.59 -0.38 1.05e-5 P wave duration; TGCT cis rs477895 0.838 rs72922039 chr11:64013116 A/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.84 7.01 0.53 1.38e-10 Mean platelet volume; TGCT trans rs4948418 0.579 rs10994321 chr10:62135206 G/A cg03916014 chr16:1722352 CRAMP1L 0.45 6.84 0.52 3.16e-10 Bipolar disorder; TGCT cis rs709400 0.628 rs2010281 chr14:103862322 G/A cg12935359 chr14:103987150 CKB -0.36 -5.38 -0.43 3.63e-7 Body mass index; TGCT cis rs909674 0.818 rs7364148 chr22:39842165 T/C cg05872129 chr22:39784769 NA -0.98 -9.55 -0.65 1.54e-16 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7781977 0.669 rs7791218 chr7:50353627 G/A cg01139861 chr7:50343298 IKZF1 0.5 5.93 0.47 2.78e-8 IgG glycosylation; TGCT cis rs8077889 1.000 rs2066725 chr17:41891473 A/G cg26893861 chr17:41843967 DUSP3 1.08 12.8 0.75 1.98e-24 Triglycerides; TGCT cis rs10782582 0.609 rs5745410 chr1:76314356 C/A cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs7926906 0.875 rs2213084 chr11:90518158 G/A cg22332266 chr11:89956777 CHORDC1 -0.42 -4.48 -0.37 1.7e-5 Intelligence (multi-trait analysis); TGCT cis rs9457247 0.967 rs387733 chr6:167409771 C/T cg23791538 chr6:167370224 RNASET2 0.5 5.14 0.42 1.02e-6 Crohn's disease; TGCT cis rs2862064 1.000 rs1354163 chr5:156420703 C/T cg12943317 chr5:156479607 HAVCR1 -0.44 -5.47 -0.44 2.35e-7 Platelet count; TGCT cis rs7666738 0.822 rs6815312 chr4:99058220 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1205863 0.749 rs1205888 chr6:11948183 T/A cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs7000551 0.675 rs2469758 chr8:22363032 C/T cg12081754 chr8:22256438 SLC39A14 0.29 4.74 0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9902453 0.904 rs6505148 chr17:28289818 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.82 7.63 0.57 5.3e-12 Coffee consumption (cups per day); TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg00080972 chr5:178986291 RUFY1 0.51 5.96 0.47 2.45e-8 Lung cancer; TGCT cis rs13326165 0.760 rs67248391 chr3:52412006 A/T cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs16958440 0.867 rs80006910 chr18:44696382 C/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs3806843 0.735 rs6849 chr5:140086191 G/T cg19875535 chr5:140030758 IK -0.37 -6.23 -0.49 6.51e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7089973 0.872 rs17092497 chr10:116612628 G/A cg03647239 chr10:116582469 FAM160B1 0.52 4.64 0.38 8.75e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7044106 0.791 rs735109 chr9:123488879 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.82 0.4 4.12e-6 Hip circumference adjusted for BMI; TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs7412746 0.611 rs111905669 chr1:150777565 T/C cg09365446 chr1:150670422 GOLPH3L 0.37 5.33 0.43 4.48e-7 Melanoma; TGCT cis rs6138458 0.701 rs6050255 chr20:25007089 A/G cg26195577 chr20:24973756 C20orf3 1.02 9.23 0.64 8.94e-16 Blood protein levels; TGCT cis rs6714710 0.603 rs895438 chr2:98382886 G/A cg26665480 chr2:98280029 ACTR1B 0.73 6.86 0.52 2.93e-10 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg10150615 chr22:24372951 LOC391322 -1.01 -13.09 -0.76 3.96e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9926296 0.605 rs12448860 chr16:89849629 T/A cg04287289 chr16:89883240 FANCA 0.93 11.56 0.72 2.07e-21 Vitiligo; TGCT trans rs7613875 0.537 rs6446195 chr3:50070853 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.8 -8.32 -0.6 1.31e-13 Body mass index; TGCT trans rs916888 0.821 rs199509 chr17:44858728 G/A cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9972944 0.783 rs9972942 chr17:63771007 A/G cg07283582 chr17:63770753 CCDC46 0.25 5.09 0.42 1.27e-6 Total body bone mineral density; TGCT cis rs7666738 0.791 rs13128640 chr4:99003918 A/C cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs992157 0.835 rs4674283 chr2:219144254 G/A cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs9902453 1.000 rs4075623 chr17:28386526 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs1129187 0.935 rs9986447 chr6:42942779 C/T cg09436375 chr6:42928200 GNMT 0.38 5.07 0.41 1.42e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4746818 1.000 rs6480384 chr10:70890757 C/T cg04149295 chr10:70884716 VPS26A 0.79 5.4 0.44 3.22e-7 Left atrial antero-posterior diameter; TGCT cis rs1865760 0.865 rs9467647 chr6:25957642 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs10791097 0.748 rs2282579 chr11:130735482 C/T cg12179176 chr11:130786555 SNX19 0.81 9.83 0.66 3.29e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9611565 0.659 rs17367716 chr22:41913844 A/G cg06481639 chr22:41940642 POLR3H -0.73 -6.64 -0.51 8.91e-10 Vitiligo; TGCT cis rs4478858 0.698 rs6655946 chr1:31805728 G/A cg07478791 chr1:31886160 SERINC2 -0.47 -4.54 -0.38 1.32e-5 Alcohol dependence; TGCT cis rs9911578 0.835 rs1990008 chr17:56459408 C/G cg12560992 chr17:57184187 TRIM37 -0.74 -8.29 -0.6 1.62e-13 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.774 rs4845681 chr1:154868055 G/T cg06418219 chr1:154948305 SHC1;CKS1B -0.68 -6.7 -0.52 6.44e-10 Prostate cancer; TGCT cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs35883536 0.545 rs115017855 chr1:101101830 T/A cg06223162 chr1:101003688 GPR88 0.32 5.34 0.43 4.31e-7 Monocyte count; TGCT cis rs4319547 0.774 rs7959238 chr12:123131498 A/T cg23029597 chr12:123009494 RSRC2 -0.27 -4.73 -0.39 6.11e-6 Body mass index; TGCT cis rs7914558 0.933 rs10786729 chr10:104719378 A/G cg04362960 chr10:104952993 NT5C2 0.6 5.38 0.44 3.56e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9926296 0.682 rs467357 chr16:89717397 A/G cg27121462 chr16:89883253 FANCA -0.55 -5.0 -0.41 1.93e-6 Vitiligo; TGCT cis rs8013055 0.846 rs35590487 chr14:105989599 C/T cg19700328 chr14:106028568 NA -0.47 -4.9 -0.4 2.91e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg11494091 chr17:61959527 GH2 0.59 13.79 0.78 8.61e-27 Prudent dietary pattern; TGCT cis rs1994135 0.647 rs11052745 chr12:33695999 G/T cg06521331 chr12:34319734 NA -0.3 -4.69 -0.39 6.97e-6 Resting heart rate; TGCT cis rs748404 0.578 rs2278856 chr15:43631356 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.48 5.0 0.41 1.93e-6 Lung cancer; TGCT cis rs931127 0.554 rs11227261 chr11:65462843 C/G cg27068330 chr11:65405492 SIPA1 -0.58 -5.16 -0.42 9.58e-7 Systemic lupus erythematosus; TGCT cis rs6582630 0.502 rs7312212 chr12:38274760 T/G cg13010199 chr12:38710504 ALG10B 0.59 4.59 0.38 1.08e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs9303542 0.625 rs6504340 chr17:46617019 A/G cg25032089 chr17:46643351 HOXB3 -0.51 -5.66 -0.45 9.85e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs2645424 0.604 rs9644756 chr8:11715100 A/T cg18999641 chr8:11876646 NA 0.23 5.0 0.41 1.88e-6 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs7959452 0.535 rs7308481 chr12:69659299 A/G cg20891283 chr12:69753455 YEATS4 0.66 6.37 0.5 3.41e-9 Blood protein levels; TGCT cis rs61990749 0.597 rs2267758 chr14:78147429 T/C cg23188588 chr14:78226832 SNW1;C14orf178 -0.67 -4.73 -0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs1406084 0.636 rs1444686 chr2:154727135 C/T cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 1.000 rs2245790 chr15:43744457 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs4972806 0.849 rs1542180 chr2:177028767 C/T cg13092806 chr2:177043255 NA 0.56 4.97 0.41 2.13e-6 IgG glycosylation; TGCT cis rs1552244 0.744 rs6763366 chr3:10033544 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs2637266 0.739 rs2579768 chr10:78415481 A/G cg18941641 chr10:78392320 NA 0.39 4.56 0.38 1.2e-5 Pulmonary function; TGCT cis rs9549367 0.713 rs3024757 chr13:113823186 G/T cg18105134 chr13:113819100 PROZ -0.47 -7.74 -0.57 3.05e-12 Platelet distribution width; TGCT cis rs7513165 0.867 rs4951318 chr1:204161513 G/C cg12731349 chr1:204159619 KISS1 0.49 5.62 0.45 1.19e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs1218582 0.772 rs12069356 chr1:154849771 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.63 -6.47 -0.5 2.08e-9 Prostate cancer; TGCT cis rs7937682 0.632 rs10789850 chr11:111750829 C/T cg09085632 chr11:111637200 PPP2R1B 0.81 7.16 0.54 6.3e-11 Primary sclerosing cholangitis; TGCT cis rs11671005 0.693 rs34023391 chr19:58913368 G/A cg13877915 chr19:58951672 ZNF132 0.66 4.9 0.4 2.94e-6 Mean platelet volume; TGCT cis rs733175 0.904 rs3775944 chr4:10019974 G/T cg11266682 chr4:10021025 SLC2A9 0.5 4.57 0.38 1.14e-5 Psychosis and Alzheimer's disease; TGCT cis rs929596 0.958 rs17862873 chr2:234646722 A/C cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.34 -4.83 -0.4 3.95e-6 Total bilirubin levels in HIV-1 infection; TGCT trans rs1814175 0.765 rs11493326 chr11:50018063 T/C cg03929089 chr4:120376271 NA -0.71 -8.08 -0.59 4.79e-13 Height; TGCT cis rs7246657 0.722 rs2909105 chr19:38167906 A/G cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs7147624 1.000 rs7160390 chr14:66052460 G/A cg03016385 chr14:66212404 NA -0.49 -7.08 -0.54 9.33e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs12600856 1 rs12600856 chr17:38163295 T/C cg17467752 chr17:38218738 THRA 0.54 5.22 0.42 7.25e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg18765753 chr7:1198926 ZFAND2A -0.53 -6.52 -0.51 1.59e-9 Longevity;Endometriosis; TGCT cis rs7666738 0.830 rs60411337 chr4:99046617 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg04389838 chr3:44770851 ZNF501 -0.37 -4.76 -0.39 5.27e-6 Depressive symptoms; TGCT cis rs61990749 0.597 rs2267759 chr14:78147615 C/T cg02301378 chr14:78227641 SNW1;C14orf178 -0.63 -4.62 -0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs2996428 0.667 rs7511793 chr1:3744249 A/G cg13057898 chr1:3703894 LRRC47 0.22 4.68 0.39 7.24e-6 Red cell distribution width; TGCT cis rs9611565 0.592 rs12484254 chr22:41962003 T/A cg06634786 chr22:41940651 POLR3H -0.88 -8.25 -0.6 1.98e-13 Vitiligo; TGCT cis rs9549260 0.755 rs9532579 chr13:41243458 T/C cg21288729 chr13:41239152 FOXO1 1.01 10.56 0.69 5.52e-19 Red blood cell count; TGCT cis rs36051895 0.695 rs11794708 chr9:5023441 G/A cg02405213 chr9:5042618 JAK2 -0.75 -10.05 -0.67 9.54e-18 Pediatric autoimmune diseases; TGCT cis rs1499614 0.803 rs1796229 chr7:66119661 G/A cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs7264396 0.733 rs6058305 chr20:34310757 C/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.27 -5.05 -0.41 1.54e-6 Total cholesterol levels; TGCT cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg18252515 chr7:66147081 NA 1.2 7.83 0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs7267979 0.966 rs2424715 chr20:25420077 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6684514 1.000 rs6684514 chr1:156255456 G/A cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs77861329 1.000 rs1237830 chr3:52202820 T/C cg08692210 chr3:52188851 WDR51A 0.93 4.79 0.4 4.61e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs12048904 0.619 rs10875346 chr1:101328083 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.69 5.64 0.45 1.1e-7 Multiple sclerosis; TGCT cis rs9653442 0.545 rs11900482 chr2:100758709 G/C cg07810366 chr2:100720526 AFF3 -0.35 -5.06 -0.41 1.48e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT trans rs7726839 0.561 rs72703046 chr5:580129 T/C cg11887960 chr12:57824829 NA 0.96 8.01 0.58 7.22e-13 Obesity-related traits; TGCT cis rs2070488 0.965 rs7640050 chr3:38525864 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 8.99 0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs6450176 0.638 rs1542167 chr5:53305742 T/G ch.5.1024479R chr5:53302184 ARL15 -0.83 -6.16 -0.48 9.32e-9 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs12497850 0.864 rs4513485 chr3:49139966 G/A cg16497277 chr3:49208875 KLHDC8B -0.49 -4.48 -0.37 1.68e-5 Parkinson's disease; TGCT cis rs2050392 0.590 rs17547917 chr10:30718303 G/A cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs17401966 0.931 rs746881 chr1:10346810 C/T cg19773385 chr1:10388646 KIF1B 0.2 4.61 0.38 9.88e-6 Hepatocellular carcinoma; TGCT cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.75 0.46 6.49e-8 Height; TGCT cis rs2243480 1.000 rs35542501 chr7:65431215 T/C cg07424592 chr7:64974309 NA 1.33 7.68 0.57 4.1e-12 Diabetic kidney disease; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg15242686 chr22:24348715 GSTTP1 -0.5 -5.8 -0.46 5.24e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs76878669 0.561 rs55998145 chr11:66152586 A/G cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.84e-9 Educational attainment (years of education); TGCT cis rs7582180 0.663 rs1114595 chr2:100960072 T/A cg14675211 chr2:100938903 LONRF2 0.47 4.57 0.38 1.16e-5 Intelligence (multi-trait analysis); TGCT cis rs6952808 0.692 rs11765549 chr7:2027311 G/T cg04267008 chr7:1944627 MAD1L1 -0.41 -5.39 -0.44 3.35e-7 Bipolar disorder and schizophrenia; TGCT cis rs9902453 0.845 rs7222842 chr17:28246943 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.28 0.55 3.32e-11 Coffee consumption (cups per day); TGCT cis rs9486715 0.867 rs4131519 chr6:96964939 G/A cg06623918 chr6:96969491 KIAA0776 1.08 14.42 0.79 2.72e-28 Headache; TGCT cis rs9549367 0.713 rs556990 chr13:113845059 T/C cg09473364 chr13:112927190 NA 0.29 4.64 0.38 8.73e-6 Platelet distribution width; TGCT cis rs7829975 0.623 rs10092965 chr8:8373485 A/G cg08975724 chr8:8085496 FLJ10661 0.58 5.42 0.44 2.99e-7 Mood instability; TGCT cis rs365132 0.818 rs6879982 chr5:176351330 A/T cg16631384 chr5:176070735 EIF4E1B -0.15 -4.64 -0.38 8.83e-6 Menarche and menopause (age at onset);Menopause (age at onset); TGCT cis rs12971120 0.891 rs3764510 chr18:72166846 A/G cg25817165 chr18:72167213 CNDP2 -0.29 -4.98 -0.41 2.05e-6 Refractive error; TGCT cis rs1552244 1.000 rs35220123 chr3:10083169 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs12477438 0.520 rs11689265 chr2:99799267 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.9 9.33 0.64 5.15e-16 Chronic sinus infection; TGCT cis rs11711311 0.955 rs2124105 chr3:113406003 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.05 -0.54 1.09e-10 IgG glycosylation; TGCT cis rs926938 0.765 rs1884296 chr1:115235716 A/C cg12756093 chr1:115239321 AMPD1 -0.42 -6.1 -0.48 1.24e-8 Autism; TGCT cis rs10972341 0.967 rs10972348 chr9:35148203 C/G cg00812861 chr9:35114699 KIAA1539 0.34 5.24 0.43 6.82e-7 Weight; TGCT cis rs4642101 0.597 rs9865624 chr3:12822786 T/A cg05775895 chr3:12838266 CAND2 0.8 9.07 0.63 2.18e-15 QRS complex (12-leadsum); TGCT trans rs2727020 0.704 rs4144700 chr11:49370834 C/A cg15704280 chr7:45808275 SEPT13 -0.74 -8.45 -0.6 6.53e-14 Coronary artery disease; TGCT cis rs6484504 0.532 rs7116443 chr11:31283170 T/C cg14844989 chr11:31128820 NA -0.24 -4.72 -0.39 6.34e-6 Red blood cell count; TGCT cis rs7772486 0.754 rs1055212 chr6:146058315 A/T cg23711669 chr6:146136114 FBXO30 -0.95 -10.87 -0.7 9.46e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs7582180 0.629 rs11686842 chr2:100956139 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs57920188 0.585 rs6696138 chr1:4073575 G/A cg20703997 chr1:4087676 NA 0.47 5.8 0.46 5.14e-8 Interleukin-17 levels; TGCT trans rs2727020 0.521 rs11040377 chr11:49474346 T/C cg03929089 chr4:120376271 NA -0.64 -7.26 -0.55 3.71e-11 Coronary artery disease; TGCT cis rs10197940 0.638 rs2288193 chr2:152348842 T/A cg06191203 chr2:152266755 RIF1 -0.79 -7.38 -0.55 1.98e-11 Lung cancer; TGCT cis rs9534288 0.699 rs2146886 chr13:46646711 C/T cg15192986 chr13:46630673 CPB2 -0.53 -6.61 -0.51 1.03e-9 Blood protein levels; TGCT cis rs3091242 0.933 rs3093584 chr1:25668714 T/C cg09222892 chr1:25734099 RHCE 0.45 7.27 0.55 3.47e-11 Erythrocyte sedimentation rate; TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg06896619 chr17:61851486 DDX42;CCDC47 0.48 4.63 0.38 9.08e-6 Prudent dietary pattern; TGCT cis rs68170813 0.559 rs3801959 chr7:106955666 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs765787 0.530 rs7167731 chr15:45510900 T/C cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT cis rs17712049 0.656 rs7795227 chr7:48198036 A/C cg16849860 chr7:48352531 ABCA13 0.27 5.05 0.41 1.51e-6 Refractive astigmatism; TGCT trans rs4332037 0.802 rs73048106 chr7:1929019 G/T cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT cis rs9467773 0.626 rs6935803 chr6:26350495 A/G cg15659132 chr6:26577336 NA -0.55 -5.68 -0.45 9.13e-8 Intelligence (multi-trait analysis); TGCT cis rs9807989 0.507 rs7605284 chr2:103044175 T/G cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs7552167 0.636 rs4090311 chr1:24513768 G/A cg01960748 chr1:24522592 NA -0.42 -4.83 -0.4 3.99e-6 Psoriasis vulgaris; TGCT cis rs2933343 0.951 rs789220 chr3:128592135 A/G cg11901034 chr3:128598214 ACAD9 0.63 5.12 0.42 1.15e-6 IgG glycosylation; TGCT cis rs9443645 0.901 rs4421161 chr6:79564219 A/G cg09184832 chr6:79620586 NA 0.47 5.24 0.43 6.69e-7 Intelligence (multi-trait analysis); TGCT cis rs12464483 0.591 rs4952170 chr2:30885429 G/A cg12454169 chr2:30669597 LCLAT1 0.5 5.35 0.43 4.07e-7 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs6952808 0.595 rs2398705 chr7:2164995 G/A cg22963979 chr7:1858916 MAD1L1 -0.4 -6.38 -0.5 3.12e-9 Bipolar disorder and schizophrenia; TGCT cis rs13392177 0.684 rs11695527 chr2:219068103 A/G cg00012203 chr2:219082015 ARPC2 0.76 7.61 0.56 6.04e-12 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs9649213 0.519 rs3735258 chr7:97866291 G/A cg09267113 chr7:98030324 BAIAP2L1 -0.77 -6.78 -0.52 4.41e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs7674212 0.570 rs2069274 chr4:104020781 C/G cg16532752 chr4:104119610 CENPE -0.56 -5.2 -0.42 8.01e-7 Type 2 diabetes; TGCT cis rs1461503 0.966 rs7944630 chr11:122838844 G/A cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs7226408 0.842 rs72885229 chr18:34406352 T/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs4727443 0.866 rs35228488 chr7:99617852 G/C cg13334819 chr7:99746414 C7orf59 0.56 4.71 0.39 6.63e-6 Interstitial lung disease; TGCT cis rs28595532 0.920 rs55794497 chr4:119764664 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7296418 0.885 rs1727305 chr12:123633382 T/C cg05973401 chr12:123451056 ABCB9 0.54 4.47 0.37 1.71e-5 Platelet count; TGCT cis rs733175 0.855 rs10023068 chr4:10004832 C/T cg11266682 chr4:10021025 SLC2A9 -0.47 -4.59 -0.38 1.09e-5 Psychosis and Alzheimer's disease; TGCT cis rs1005277 0.540 rs2224248 chr10:38451886 A/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.23 -0.59 2.17e-13 Extrinsic epigenetic age acceleration; TGCT cis rs881375 0.678 rs7037195 chr9:123684000 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.47 5.18 0.42 8.53e-7 Rheumatoid arthritis; TGCT cis rs778371 0.697 rs2344611 chr2:233581937 A/G cg08000102 chr2:233561755 GIGYF2 0.69 7.85 0.58 1.69e-12 Schizophrenia; TGCT cis rs10464366 0.746 rs12670510 chr7:39142146 A/G cg15212455 chr7:39170539 POU6F2 0.26 5.62 0.45 1.19e-7 IgG glycosylation; TGCT cis rs8013055 0.796 rs4075105 chr14:106000231 C/T cg23356831 chr14:105996513 TMEM121 0.34 5.31 0.43 4.91e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7607369 0.637 rs3888879 chr2:219290676 C/T cg02176678 chr2:219576539 TTLL4 -0.49 -6.29 -0.49 4.85e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs10746514 0.833 rs2026302 chr1:232264047 A/G cg09506761 chr1:232265262 NA -0.49 -4.99 -0.41 2.01e-6 Response to statin therapy; TGCT cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 14.32 0.79 4.83e-28 Prudent dietary pattern; TGCT cis rs4746059 0.516 rs12358019 chr10:72470176 C/T cg03087610 chr10:71892362 AIFM2 -0.51 -4.5 -0.37 1.54e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs950169 0.580 rs62021208 chr15:85196244 G/A cg17173187 chr15:85201210 NMB 0.59 6.75 0.52 5.05e-10 Schizophrenia; TGCT cis rs1153858 0.943 rs12439575 chr15:45684816 T/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs9303401 0.659 rs35539277 chr17:56853833 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs1167827 1.000 rs1167827 chr7:75163169 A/G cg04681579 chr7:75027559 TRIM73;TRIM74 -0.41 -4.82 -0.4 4.19e-6 Body mass index;BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6598955 0.617 rs11247883 chr1:26576247 T/G cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs3772130 1.000 rs35988617 chr3:121432902 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.85 0.4 3.66e-6 Cognitive performance; TGCT cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg03517284 chr6:25882590 NA -0.64 -5.74 -0.46 6.84e-8 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs560854 chr11:95584905 G/A cg25478527 chr11:95522999 CEP57;FAM76B 0.47 4.46 0.37 1.85e-5 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7772486 0.686 rs6570705 chr6:145961201 C/T cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs12765878 0.580 rs10786772 chr10:105610326 A/G cg11005552 chr10:105648138 OBFC1 0.38 5.98 0.47 2.17e-8 Coronary artery disease; TGCT trans rs1499614 1.000 rs2707840 chr7:66158015 C/T cg07424592 chr7:64974309 NA 1.35 8.05 0.59 5.72e-13 Gout; TGCT cis rs826838 1.000 rs1719848 chr12:39085586 A/G cg26384229 chr12:38710491 ALG10B -0.85 -8.09 -0.59 4.68e-13 Heart rate; TGCT cis rs56114371 0.530 rs9348774 chr6:27688930 C/T cg10876282 chr6:28092338 ZSCAN16 0.64 5.29 0.43 5.39e-7 Breast cancer; TGCT cis rs7412746 0.658 rs11582281 chr1:150826831 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 4.98 0.41 2.11e-6 Melanoma; TGCT cis rs2479724 0.840 rs6925777 chr6:41750822 C/T cg08135965 chr6:41755394 TOMM6 -0.49 -4.77 -0.39 5e-6 Menarche (age at onset); TGCT cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs933688 1.000 rs2059207 chr5:90731931 C/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.88 8.2 0.59 2.51e-13 Smoking behavior; TGCT cis rs17401966 0.838 rs12737239 chr1:10323973 C/G cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs17030434 1.000 rs75083896 chr4:154719082 A/G cg14289246 chr4:154710475 SFRP2 -0.91 -7.2 -0.54 5.18e-11 Electrocardiographic conduction measures; TGCT cis rs7772486 0.686 rs857879 chr6:145974043 C/A cg23711669 chr6:146136114 FBXO30 -0.83 -8.98 -0.63 3.75e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs9814567 1.000 rs9989967 chr3:134238964 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -9.2 -0.64 1.11e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7017914 0.905 rs3110246 chr8:71934613 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs17345786 0.906 rs72946021 chr3:101250008 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.85 8.66 0.61 2.16e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs7826238 0.720 rs12546760 chr8:8374836 A/G cg08975724 chr8:8085496 FLJ10661 -0.57 -5.25 -0.43 6.53e-7 Systolic blood pressure; TGCT cis rs7666738 0.830 rs11727653 chr4:99001774 T/C cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs11083475 0.714 rs1471432 chr19:39260282 G/A cg17759274 chr19:39260954 NA 0.34 4.55 0.38 1.28e-5 Heart rate; TGCT cis rs4891159 0.548 rs690414 chr18:74117840 T/C cg24786174 chr18:74118243 ZNF516 0.71 15.66 0.82 3.6e-31 Longevity; TGCT cis rs2075165 0.870 rs12128955 chr1:156243821 C/T cg16558208 chr1:156270281 VHLL 0.27 4.74 0.39 5.65e-6 Tonsillectomy; TGCT cis rs2762353 0.808 rs1185978 chr6:25835895 A/G cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.62e-9 Blood metabolite levels; TGCT cis rs2932538 1.000 rs2932538 chr1:113216543 A/G cg22162597 chr1:113214053 CAPZA1 -0.28 -6.31 -0.49 4.46e-9 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs4819052 1.000 rs9306123 chr21:46709922 A/G cg06618935 chr21:46677482 NA -0.38 -4.97 -0.41 2.22e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3749237 1.000 rs11130216 chr3:49736172 C/A cg10152585 chr3:50297680 NA 0.49 4.47 0.37 1.77e-5 Resting heart rate; TGCT cis rs4665809 0.941 rs3177055 chr2:26359315 G/A cg25036284 chr2:26402008 FAM59B -0.55 -4.58 -0.38 1.14e-5 Gut microbiome composition (summer); TGCT cis rs17102423 0.826 rs10873181 chr14:65604459 A/C cg11161011 chr14:65562177 MAX -0.49 -6.78 -0.52 4.38e-10 Obesity-related traits; TGCT cis rs7119038 0.865 rs10892299 chr11:118726843 C/T cg19308663 chr11:118741387 NA 0.31 5.86 0.47 3.87e-8 Sjögren's syndrome; TGCT cis rs2115630 0.967 rs11073731 chr15:85355113 C/A cg17173187 chr15:85201210 NMB -0.39 -4.79 -0.39 4.76e-6 P wave terminal force; TGCT cis rs35146811 0.735 rs1636978 chr7:99813912 G/A cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs7246657 0.722 rs968073 chr19:38192021 G/A cg03611452 chr19:38183253 ZNF781 -0.56 -4.63 -0.38 8.97e-6 Coronary artery calcification; TGCT cis rs6089829 0.962 rs11086151 chr20:61664644 C/T cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7582180 0.629 rs4851296 chr2:100949570 T/C cg14675211 chr2:100938903 LONRF2 0.53 5.16 0.42 9.36e-7 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.931 rs4974080 chr3:49030828 A/C cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.97e-6 Parkinson's disease; TGCT cis rs7959452 0.590 rs11177619 chr12:69758871 G/A cg14784868 chr12:69753453 YEATS4 0.83 8.85 0.62 7.59e-15 Blood protein levels; TGCT cis rs9467711 0.651 rs13206443 chr6:26119245 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.57 -4.54 -0.38 1.33e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs7095607 0.967 rs7095603 chr10:69957340 G/A cg18986048 chr10:69913749 MYPN 0.46 4.93 0.41 2.54e-6 Lung function (FVC); TGCT cis rs1903068 0.853 rs73236111 chr4:56019068 A/C cg16572876 chr4:56024045 NA 0.44 4.8 0.4 4.5e-6 Endometriosis; TGCT cis rs362272 0.524 rs2857982 chr4:3358665 G/A cg18352616 chr4:3374830 RGS12 0.23 4.54 0.38 1.31e-5 Serum sulfate level; TGCT cis rs9611565 0.765 rs132920 chr22:41810170 T/C cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs1903068 0.853 rs28838369 chr4:56007249 A/G cg01777861 chr4:56023843 NA 0.55 6.18 0.49 8.58e-9 Endometriosis; TGCT cis rs10489202 0.657 rs201541 chr1:167992344 T/A cg24449463 chr1:168025552 DCAF6 -0.61 -7.19 -0.54 5.24e-11 Schizophrenia; TGCT cis rs9372498 0.536 rs9489460 chr6:118925754 C/T cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg15242686 chr22:24348715 GSTTP1 0.44 5.88 0.47 3.64e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2762353 0.574 rs9467574 chr6:25705718 C/G cg07061783 chr6:25882402 NA 0.72 7.17 0.54 5.98e-11 Blood metabolite levels; TGCT cis rs2580764 0.566 rs2920878 chr2:55296415 C/T cg09592903 chr2:55203963 RTN4 0.25 5.79 0.46 5.55e-8 Mean platelet volume; TGCT cis rs12188164 1.000 rs56104584 chr5:437542 T/C cg26850624 chr5:429559 AHRR -0.2 -4.82 -0.4 4.05e-6 Cystic fibrosis severity; TGCT cis rs7954584 0.545 rs12824593 chr12:122374108 G/A cg22618164 chr12:122356400 WDR66 0.69 6.52 0.51 1.6e-9 Mean corpuscular volume; TGCT cis rs344364 0.511 rs2982449 chr16:1947878 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs6598955 0.724 rs3924934 chr1:26644079 A/G cg04990556 chr1:26633338 UBXN11 -0.92 -11.21 -0.71 1.46e-20 Obesity-related traits; TGCT cis rs12210905 0.920 rs9348759 chr6:27290888 C/T cg08851530 chr6:28072375 NA 1.29 5.45 0.44 2.65e-7 Hip circumference adjusted for BMI; TGCT cis rs35160687 0.871 rs2278105 chr2:86466516 A/G cg12542933 chr2:85804724 VAMP8 0.4 4.77 0.39 5.15e-6 Night sleep phenotypes; TGCT cis rs11190604 1.000 rs6584379 chr10:102224490 G/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs13118159 0.801 rs7690727 chr4:1340811 C/A cg20887711 chr4:1340912 KIAA1530 0.6 5.38 0.44 3.5e-7 Longevity; TGCT cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs28712821 0.930 rs11940694 chr4:39414993 C/T cg12062995 chr4:39368212 RFC1 -0.4 -4.8 -0.4 4.41e-6 Alcohol consumption; TGCT cis rs394563 0.726 rs6906384 chr6:149664540 G/A cg11245181 chr6:149772854 ZC3H12D 0.29 4.84 0.4 3.77e-6 Dupuytren's disease; TGCT cis rs11122272 0.735 rs2808596 chr1:231530723 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT trans rs6069325 0.529 rs6069323 chr20:54139209 C/G cg26869512 chr4:8389770 ACOX3 0.47 6.92 0.53 2.12e-10 Motion sickness; TGCT cis rs3806843 1.000 rs2240695 chr5:140168151 G/T cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7772486 0.790 rs10223507 chr6:146285204 C/A cg23711669 chr6:146136114 FBXO30 -0.87 -9.97 -0.67 1.5e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.546 rs10026181 chr4:98814118 C/T cg18180107 chr4:99064573 C4orf37 -0.57 -4.83 -0.4 3.9e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.808 rs74600494 chr2:43743491 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.78 4.84 0.4 3.8e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs12599106 0.629 rs1391904 chr16:34548934 C/T cg03395511 chr6:291903 DUSP22 -0.65 -6.78 -0.52 4.28e-10 Menopause (age at onset); TGCT cis rs1008375 1.000 rs7671752 chr4:17661398 C/T cg18681998 chr4:17616180 MED28 0.96 11.17 0.71 1.81e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg18110333 chr6:292329 DUSP22 -0.72 -7.63 -0.57 5.43e-12 Menopause (age at onset); TGCT cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg04389838 chr3:44770851 ZNF501 -0.37 -4.83 -0.4 4.02e-6 Depressive symptoms; TGCT cis rs6754311 0.773 rs666407 chr2:136640233 A/G cg07169764 chr2:136633963 MCM6 0.64 6.0 0.47 1.99e-8 Mosquito bite size; TGCT cis rs12188164 1.000 rs12188678 chr5:428231 T/C cg26850624 chr5:429559 AHRR -0.2 -4.69 -0.39 7.1e-6 Cystic fibrosis severity; TGCT cis rs4700695 0.545 rs253275 chr5:65509809 A/G cg21114390 chr5:65439923 SFRS12 -0.81 -7.72 -0.57 3.39e-12 Facial morphology (factor 19); TGCT cis rs7927771 0.864 rs2053979 chr11:47439444 A/G cg10139015 chr11:47448256 PSMC3 0.52 4.46 0.37 1.78e-5 Subjective well-being; TGCT cis rs908922 0.676 rs4845443 chr1:152507156 C/T cg20991723 chr1:152506922 NA 0.46 6.3 0.49 4.77e-9 Hair morphology; TGCT cis rs514406 0.505 rs374662 chr1:53164549 C/A cg25767906 chr1:53392781 SCP2 -0.45 -4.85 -0.4 3.59e-6 Monocyte count; TGCT cis rs72700829 0.531 rs12070288 chr1:151009984 C/G cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Schizophrenia; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg23131131 chr22:24373011 LOC391322 -0.67 -7.05 -0.53 1.11e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7829975 0.593 rs2921061 chr8:8317615 A/T cg06636001 chr8:8085503 FLJ10661 0.77 7.52 0.56 9.75e-12 Mood instability; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.5 4.61 0.38 9.7e-6 Prudent dietary pattern; TGCT cis rs2013441 0.931 rs12937827 chr17:20033202 G/C cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs1153858 1.000 rs7171577 chr15:45627979 G/A cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs2762353 0.776 rs765285 chr6:25828242 G/C cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.63e-9 Blood metabolite levels; TGCT cis rs2013441 1.000 rs9915059 chr17:20177104 G/T cg18979559 chr17:20280153 CCDC144C -0.48 -4.69 -0.39 7.09e-6 Obesity-related traits; TGCT cis rs8077577 0.836 rs58441148 chr17:18106498 T/A cg09161412 chr17:18057145 MYO15A -0.64 -5.22 -0.42 7.2e-7 Obesity-related traits; TGCT cis rs6500602 0.627 rs934929 chr16:4587789 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.4 -7.18 -0.54 5.64e-11 Schizophrenia; TGCT cis rs295140 0.506 rs295136 chr2:201141002 G/C cg23649088 chr2:200775458 C2orf69 0.28 4.59 0.38 1.06e-5 QT interval; TGCT cis rs12477438 0.520 rs2171359 chr2:99795360 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs2180341 1.000 rs6569486 chr6:127708424 A/C cg24812749 chr6:127587940 RNF146 0.99 7.63 0.57 5.24e-12 Breast cancer; TGCT cis rs7818688 0.697 rs58314911 chr8:95985111 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs6076065 0.748 rs999068 chr20:23376483 G/A cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs916888 0.610 rs199442 chr17:44820122 G/A cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.64 4.95 0.41 2.39e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs763121 0.962 rs1980455 chr22:38925719 A/C cg06022373 chr22:39101656 GTPBP1 0.75 7.53 0.56 9.08e-12 Menopause (age at onset); TGCT cis rs7666738 0.830 rs10516426 chr4:99035827 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs801193 1.000 rs3800812 chr7:66223461 T/C cg00343986 chr7:65444356 GUSB 0.23 5.13 0.42 1.08e-6 Aortic root size; TGCT cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg23758822 chr17:41437982 NA 0.69 6.36 0.5 3.54e-9 Menopause (age at onset); TGCT cis rs9512730 0.553 rs6491213 chr13:28049822 T/C cg04070771 chr13:27998621 GTF3A 0.52 4.57 0.38 1.18e-5 Schizophrenia; TGCT cis rs62380364 0.558 rs34319 chr5:88023349 A/T cg22951263 chr5:87985283 NA -0.54 -5.78 -0.46 5.76e-8 Intelligence (multi-trait analysis); TGCT cis rs34172651 0.517 rs12920774 chr16:24830750 T/C cg06028605 chr16:24865363 SLC5A11 0.41 4.47 0.37 1.76e-5 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.731 rs10873787 chr1:76367797 G/A cg10523679 chr1:76189770 ACADM 0.85 7.54 0.56 8.71e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2025751 0.692 rs9474103 chr6:51696869 A/G cg23457901 chr6:52402140 TRAM2 -0.22 -4.45 -0.37 1.85e-5 Intraocular pressure; TGCT cis rs546131 0.642 rs568529 chr11:34842506 C/A cg06937548 chr11:34938143 PDHX;APIP 0.51 4.51 0.38 1.46e-5 Lung disease severity in cystic fibrosis; TGCT cis rs7264396 0.690 rs2425180 chr20:34447160 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs6933660 0.720 rs6914656 chr6:151753421 C/G cg10883421 chr6:151773342 RMND1;C6orf211 0.64 6.4 0.5 2.87e-9 Menarche (age at onset); TGCT cis rs2013441 1.000 rs2034109 chr17:20196633 C/T cg23224458 chr17:20280056 CCDC144C -0.42 -4.91 -0.4 2.82e-6 Obesity-related traits; TGCT cis rs9929218 0.551 rs3785135 chr16:68728976 A/C cg01251360 chr16:68772225 CDH1 0.27 5.25 0.43 6.5e-7 Colorectal cancer; TGCT cis rs4755351 0.553 rs11032157 chr11:33158566 A/G cg14646457 chr11:33280348 HIPK3 -0.91 -4.85 -0.4 3.55e-6 Lung cancer in ever smokers; TGCT cis rs9733 0.818 rs12403609 chr1:150676485 T/C cg13175981 chr1:150552382 MCL1 0.43 4.78 0.39 4.77e-6 Tonsillectomy; TGCT cis rs3091242 0.809 rs660129 chr1:25727438 C/T cg09222892 chr1:25734099 RHCE -0.44 -7.09 -0.54 9.15e-11 Erythrocyte sedimentation rate; TGCT cis rs11098499 0.863 rs11723090 chr4:120490592 T/C cg09307838 chr4:120376055 NA 0.68 6.47 0.5 2.02e-9 Corneal astigmatism; TGCT cis rs9653442 0.545 rs11123814 chr2:100767082 A/G cg22139774 chr2:100720529 AFF3 -0.34 -5.4 -0.44 3.21e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs614226 0.935 rs77955762 chr12:121009948 T/C cg01236616 chr12:121019343 POP5 -1.29 -12.97 -0.76 7.75e-25 Type 1 diabetes nephropathy; TGCT cis rs9486719 0.948 rs2472906 chr6:96875318 G/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs5769765 0.908 rs9616376 chr22:50310829 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs7568458 0.811 rs3755014 chr2:85764006 C/T cg02493740 chr2:85810744 VAMP5 -0.29 -5.46 -0.44 2.47e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg01448562 chr3:133502909 NA 0.26 4.91 0.4 2.81e-6 Iron status biomarkers; TGCT cis rs9372498 0.908 rs17080082 chr6:118700137 C/T cg21191810 chr6:118973309 C6orf204 -0.5 -4.61 -0.38 9.92e-6 Diastolic blood pressure; TGCT trans rs11722228 0.508 rs3756227 chr4:10087995 C/A cg26043149 chr18:55253948 FECH 1.12 11.04 0.7 3.79e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs9467711 0.516 rs1177441 chr6:25859413 A/G cg12310025 chr6:25882481 NA -0.72 -4.77 -0.39 5.17e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs597539 0.652 rs496616 chr11:68672800 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.16 0.59 3.19e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9814567 1.000 rs7371896 chr3:134249769 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4665809 0.590 rs3806515 chr2:26466975 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs66887589 0.934 rs41464847 chr4:120532401 A/G cg24670566 chr4:120433619 PDE5A -0.24 -4.48 -0.37 1.67e-5 Diastolic blood pressure; TGCT cis rs875971 0.660 rs13224319 chr7:66007363 A/G cg18876405 chr7:65276391 NA 0.36 5.41 0.44 3.12e-7 Aortic root size; TGCT cis rs6087990 0.836 rs2424909 chr20:31361861 T/C cg13636640 chr20:31349939 DNMT3B 1.08 14.21 0.79 8.84e-28 Ulcerative colitis; TGCT cis rs6089829 0.890 rs6062775 chr20:61663650 T/C cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs11648796 0.765 rs61112891 chr16:783156 G/C cg00908189 chr16:619842 PIGQ 0.65 4.79 0.39 4.75e-6 Height; TGCT cis rs9467711 0.932 rs11966360 chr6:26316982 A/G cg16898833 chr6:26189333 HIST1H4D 1.0 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7172809 0.599 rs2012756 chr15:77745301 G/C cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs6669384 0.774 rs4844622 chr1:208034329 C/T cg22525895 chr1:207977042 MIR29B2 -0.39 -5.45 -0.44 2.57e-7 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT trans rs1005277 0.557 rs1854563 chr10:38434961 G/A cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.5e-21 Extrinsic epigenetic age acceleration; TGCT cis rs2735413 0.564 rs8051817 chr16:78121254 C/T cg09132178 chr16:78079569 NA 0.35 4.51 0.38 1.47e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs2420915 0.841 rs2254455 chr10:122872517 G/A cg23234726 chr10:122735589 NA -0.32 -4.48 -0.37 1.67e-5 Fibrinogen levels; TGCT cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg09222892 chr1:25734099 RHCE 0.42 6.78 0.52 4.33e-10 Erythrocyte sedimentation rate; TGCT cis rs394563 0.726 rs366905 chr6:149735097 T/A cg03678062 chr6:149772716 ZC3H12D -0.39 -4.83 -0.4 4.02e-6 Dupuytren's disease; TGCT cis rs4478858 0.735 rs10914360 chr1:31817476 G/A cg07478791 chr1:31886160 SERINC2 -0.47 -4.54 -0.38 1.32e-5 Alcohol dependence; TGCT cis rs10779751 0.734 rs1194820 chr1:11129259 A/C cg08854313 chr1:11322531 MTOR 0.84 8.29 0.6 1.55e-13 Body mass index; TGCT trans rs10802346 0.515 rs1113270 chr1:246423217 A/G cg13514129 chr1:39547527 MACF1 1.02 9.4 0.65 3.68e-16 Fractional exhaled nitric oxide (childhood); TGCT cis rs12908161 1.000 rs12903134 chr15:85337699 T/A cg11189052 chr15:85197271 WDR73 0.71 5.87 0.47 3.68e-8 Schizophrenia; TGCT cis rs10504229 0.683 rs6999131 chr8:58127052 C/A cg20607798 chr8:58055168 NA 0.58 4.89 0.4 3.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs7917772 0.582 rs12779854 chr10:104358474 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.46 -0.44 2.51e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9486719 1.000 rs2499809 chr6:96870110 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs10876993 0.890 rs774888 chr12:58036506 A/G cg15848620 chr12:58087721 OS9 -0.72 -5.78 -0.46 5.57e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs992157 0.764 rs2382827 chr2:219184387 G/A cg00012203 chr2:219082015 ARPC2 0.7 6.59 0.51 1.11e-9 Colorectal cancer; TGCT cis rs2663905 0.706 rs2683260 chr15:81385552 A/C cg27045999 chr15:81426544 C15orf26 -0.64 -5.78 -0.46 5.63e-8 QT interval (drug interaction); TGCT trans rs1814175 0.817 rs2866545 chr11:49630824 A/C cg03929089 chr4:120376271 NA -0.74 -8.69 -0.62 1.75e-14 Height; TGCT cis rs12477438 0.748 rs6712773 chr2:99585781 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs9916302 0.904 rs587343 chr17:37440603 C/T cg07936489 chr17:37558343 FBXL20 0.6 4.75 0.39 5.45e-6 Glomerular filtration rate (creatinine); TGCT cis rs12220898 0.679 rs4838485 chr10:50484825 T/A cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs36051895 0.558 rs7038687 chr9:5134065 C/T cg02405213 chr9:5042618 JAK2 0.79 11.01 0.7 4.46e-20 Pediatric autoimmune diseases; TGCT cis rs1552244 1.000 rs67852463 chr3:10157205 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs17030434 0.871 rs6847648 chr4:154729700 G/A cg14289246 chr4:154710475 SFRP2 -0.9 -7.56 -0.56 7.62e-12 Electrocardiographic conduction measures; TGCT cis rs72843506 0.722 rs79590067 chr17:20107414 G/A cg18979559 chr17:20280153 CCDC144C -0.64 -4.84 -0.4 3.71e-6 Schizophrenia; TGCT cis rs9913156 0.802 rs4538065 chr17:4566015 G/A cg19197139 chr17:4613644 ARRB2 -0.87 -8.05 -0.59 5.79e-13 Lymphocyte counts; TGCT trans rs877282 0.898 rs34490091 chr10:765800 A/C cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs1799949 1.000 rs8077486 chr17:41212805 C/T cg23758822 chr17:41437982 NA 0.72 6.99 0.53 1.47e-10 Menopause (age at onset); TGCT cis rs2580764 0.540 rs2920893 chr2:55270629 C/T cg09592903 chr2:55203963 RTN4 0.27 6.06 0.48 1.51e-8 Mean platelet volume; TGCT cis rs709400 0.628 rs6575984 chr14:103876454 A/G cg12935359 chr14:103987150 CKB 0.34 5.19 0.42 8.36e-7 Body mass index; TGCT cis rs12148488 0.738 rs4886417 chr15:75330159 T/G cg09165964 chr15:75287851 SCAMP5 0.52 4.56 0.38 1.21e-5 Caffeine consumption; TGCT cis rs11122272 0.735 rs2739515 chr1:231514681 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT trans rs9650657 0.535 rs7011756 chr8:11019578 C/G cg06636001 chr8:8085503 FLJ10661 -0.8 -7.48 -0.56 1.18e-11 Neuroticism; TGCT cis rs208520 0.770 rs1342960 chr6:66883514 T/C cg07460842 chr6:66804631 NA -0.9 -9.36 -0.64 4.37e-16 Exhaled nitric oxide output; TGCT cis rs2178146 0.535 rs4843946 chr16:86445827 A/G cg11165158 chr16:86613094 FOXL1 -0.36 -4.92 -0.4 2.71e-6 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT cis rs13326165 0.715 rs11716017 chr3:52380991 C/T cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.36e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs12142240 0.698 rs66847432 chr1:46832013 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.8 -0.4 4.46e-6 Menopause (age at onset); TGCT cis rs3820928 0.845 rs13415319 chr2:227878936 G/C cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.13e-5 Pulmonary function; TGCT cis rs425277 0.583 rs925905 chr1:2044037 T/C cg24578937 chr1:2090814 PRKCZ -0.24 -5.84 -0.46 4.38e-8 Height; TGCT cis rs12464483 0.524 rs1901906 chr2:30884576 A/G cg12454169 chr2:30669597 LCLAT1 -0.45 -4.88 -0.4 3.17e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs2191566 1.000 rs7256908 chr19:44528898 C/T cg03039196 chr19:44506973 ZNF230 0.57 4.91 0.4 2.87e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs2204008 0.837 rs7308714 chr12:38274307 T/C cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.19e-11 Bladder cancer; TGCT trans rs6951245 0.554 rs4724294 chr7:1139695 G/A cg13565492 chr6:43139072 SRF -0.82 -7.72 -0.57 3.43e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs6920965 0.583 rs9388456 chr6:126147197 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.6 -6.71 -0.52 6.23e-10 High light scatter reticulocyte count; TGCT cis rs12477438 0.765 rs7591992 chr2:99668954 A/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT trans rs1814175 0.817 rs11518158 chr11:49985633 G/T cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.25e-14 Height; TGCT cis rs1552244 0.882 rs6443279 chr3:10053599 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.98 0.47 2.23e-8 Alzheimer's disease; TGCT cis rs9858542 0.903 rs35999162 chr3:49597230 C/G cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs950169 0.580 rs36126054 chr15:85177723 T/G cg17173187 chr15:85201210 NMB 0.62 7.09 0.54 8.99e-11 Schizophrenia; TGCT cis rs4319547 0.688 rs10847415 chr12:123144293 T/C cg23029597 chr12:123009494 RSRC2 -0.3 -5.14 -0.42 1.02e-6 Body mass index; TGCT cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg09177884 chr7:1199841 ZFAND2A -0.53 -5.09 -0.42 1.31e-6 Longevity;Endometriosis; TGCT cis rs8056742 0.730 rs62048415 chr16:85063709 G/A cg00229868 chr16:85520891 NA 0.4 5.45 0.44 2.65e-7 Amyotrophic lateral sclerosis; TGCT cis rs3784262 0.565 rs2642632 chr15:58308254 C/A cg12031962 chr15:58353849 ALDH1A2 -0.38 -5.43 -0.44 2.8e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs13256369 0.851 rs11249889 chr8:8564992 G/T cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs2463822 0.925 rs6863 chr11:62160725 G/T cg06239285 chr11:62104954 ASRGL1 -0.8 -5.2 -0.42 8.1e-7 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs1865760 0.566 rs9295686 chr6:26081983 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs3008870 1.000 rs2985824 chr1:67410171 C/T cg11518657 chr1:67396239 MIER1 -0.53 -4.63 -0.38 9.2e-6 Lymphocyte percentage of white cells; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg27535305 chr1:53392650 SCP2 -0.26 -5.25 -0.43 6.37e-7 Monocyte count; TGCT cis rs1499614 0.901 rs3936 chr7:66126489 C/T cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs9611565 0.573 rs9306355 chr22:42111896 A/T cg06481639 chr22:41940642 POLR3H 0.56 4.87 0.4 3.39e-6 Vitiligo; TGCT cis rs6570726 0.935 rs376991 chr6:145828073 G/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs12477438 0.520 rs7605843 chr2:99811894 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.88 8.83 0.62 8.31e-15 Chronic sinus infection; TGCT cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg04013166 chr16:89971882 TCF25 0.33 4.64 0.38 8.86e-6 Skin colour saturation; TGCT trans rs4919669 0.546 rs4919652 chr10:104274157 A/C cg19053889 chr7:1098703 C7orf50;GPR146 -0.51 -6.78 -0.52 4.25e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT trans rs9388451 0.805 rs1028481 chr6:126106573 G/T cg05039488 chr6:79577232 IRAK1BP1 -0.72 -8.04 -0.59 6.03e-13 Brugada syndrome; TGCT cis rs7917772 0.582 rs7907417 chr10:104370662 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.36 -0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9549260 0.755 rs9577091 chr13:41227865 G/A cg21288729 chr13:41239152 FOXO1 1.01 10.71 0.69 2.36e-19 Red blood cell count; TGCT cis rs6840360 0.642 rs1470280 chr4:152431770 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs910316 1.000 rs7145159 chr14:75583268 A/G cg11812906 chr14:75593930 NEK9 0.74 7.28 0.55 3.42e-11 Height; TGCT cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.67 5.58 0.45 1.43e-7 Intelligence (multi-trait analysis); TGCT cis rs909002 0.889 rs1061392 chr1:32118160 C/A cg11573219 chr1:32083031 HCRTR1 -0.48 -5.92 -0.47 2.92e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs28485415 chr4:99060340 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7586879 0.575 rs6712981 chr2:25126230 A/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs6674176 0.551 rs2242637 chr1:44401384 A/G cg12908607 chr1:44402522 ARTN -0.69 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs3008870 1.000 rs2985794 chr1:67425311 T/G cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs1045714 0.836 rs56246161 chr7:2644679 G/A cg17215154 chr7:2644645 IQCE 0.26 4.57 0.38 1.18e-5 Urate levels in lean individuals; TGCT cis rs55962025 0.804 rs362268 chr4:3242148 C/G cg06533319 chr4:3265114 C4orf44 0.23 4.53 0.38 1.34e-5 Parental longevity (mother's age at death); TGCT trans rs17685 0.884 rs3823882 chr7:75631913 T/C cg19862616 chr7:65841803 NCRNA00174 -0.47 -7.26 -0.55 3.81e-11 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs3960554 0.569 rs11973658 chr7:75882026 A/C cg19105122 chr7:75896889 SRRM3 0.62 5.32 0.43 4.78e-7 Eotaxin levels; TGCT cis rs9640161 0.830 rs3757423 chr7:150067714 A/G cg10018233 chr7:150070692 REPIN1 -0.41 -6.8 -0.52 3.84e-10 Blood protein levels;Circulating chemerin levels; TGCT cis rs7246657 0.882 rs10422667 chr19:37937876 T/C cg18154014 chr19:37997991 ZNF793 0.94 6.56 0.51 1.3e-9 Coronary artery calcification; TGCT trans rs8073060 0.927 rs7502331 chr17:33868858 A/G cg19694781 chr19:47549865 TMEM160 0.43 7.85 0.58 1.71e-12 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs611744 0.507 rs2121900 chr8:109333542 T/C cg21045802 chr8:109455806 TTC35 0.76 7.76 0.57 2.7e-12 Dupuytren's disease; TGCT cis rs7666738 0.830 rs62318472 chr4:98926030 G/A cg18180107 chr4:99064573 C4orf37 0.55 4.98 0.41 2.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs67072384 0.786 rs60497375 chr11:72452645 A/G cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs11785400 0.701 rs9297968 chr8:143723009 A/G cg24634471 chr8:143751801 JRK 0.53 5.24 0.43 6.7e-7 Schizophrenia; TGCT cis rs7806994 1 rs7806994 chr7:56139505 A/T cg23942717 chr7:56437746 NA 0.48 4.99 0.41 1.99e-6 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.765 rs1974435 chr17:61994096 G/A cg22520471 chr17:61851767 DDX42;CCDC47 -0.53 -5.1 -0.42 1.26e-6 Prudent dietary pattern; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg10150615 chr22:24372951 LOC391322 -0.96 -11.46 -0.72 3.58e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2404602 0.692 rs12595586 chr15:77172210 A/G cg26408565 chr15:76604113 ETFA -0.36 -4.52 -0.38 1.41e-5 Blood metabolite levels; TGCT cis rs71597109 0.568 rs11940179 chr4:102727577 C/T cg14855874 chr4:102712397 BANK1 0.41 4.72 0.39 6.16e-6 Chronic lymphocytic leukemia; TGCT cis rs1865760 0.964 rs1324084 chr6:25915134 C/T cg16482183 chr6:26056742 HIST1H1C 0.52 4.6 0.38 1.04e-5 Height; TGCT cis rs7044106 0.734 rs1981020 chr9:123388464 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.57 0.38 1.14e-5 Hip circumference adjusted for BMI; TGCT trans rs941408 1.000 rs1736179 chr19:2795516 T/A cg19676328 chr12:49525230 TUBA1B -0.76 -7.65 -0.57 4.74e-12 Total cholesterol levels; TGCT cis rs9837602 0.507 rs793452 chr3:99529523 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 -0.57 -6.61 -0.51 9.98e-10 Breast cancer; TGCT cis rs597539 0.652 rs478647 chr11:68700424 C/T cg21862992 chr11:68658383 NA 0.44 6.07 0.48 1.42e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12479064 0.724 rs10496336 chr2:99996165 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.57 -4.47 -0.37 1.71e-5 Chronic sinus infection; TGCT cis rs13177918 0.626 rs67026795 chr5:149831660 T/C cg14059543 chr5:149831962 NA -0.68 -9.02 -0.63 2.93e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg18538332 chr22:24372958 LOC391322 0.75 6.21 0.49 7.22e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs910316 0.687 rs11627442 chr14:75669649 A/G cg11812906 chr14:75593930 NEK9 -0.55 -4.74 -0.39 5.72e-6 Height; TGCT trans rs629535 0.783 rs510632 chr8:70034570 A/G cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs9611519 1.000 rs5758267 chr22:41619350 A/T cg13695892 chr22:41940480 POLR3H 0.52 4.79 0.39 4.74e-6 Neuroticism; TGCT cis rs7772486 0.713 rs1986729 chr6:146194831 G/A cg13319975 chr6:146136371 FBXO30 -0.54 -4.81 -0.4 4.27e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6964587 1.000 rs6944591 chr7:91642714 T/C cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs651907 0.535 rs9830943 chr3:101428899 T/G cg12386194 chr3:101231763 SENP7 0.48 4.6 0.38 1.04e-5 Colorectal cancer; TGCT cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg04944784 chr2:26401820 FAM59B -0.72 -5.92 -0.47 2.93e-8 Gut microbiome composition (summer); TGCT cis rs6964587 0.967 rs12535601 chr7:91718346 A/G cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs939574 0.790 rs72955452 chr2:220101783 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.03 4.62 0.38 9.29e-6 Platelet distribution width; TGCT cis rs4788570 0.566 rs72795864 chr16:71483497 C/G cg06353428 chr16:71660113 MARVELD3 -1.33 -7.91 -0.58 1.24e-12 Intelligence (multi-trait analysis); TGCT cis rs12681288 0.782 rs6559213 chr8:1030923 A/G cg04851639 chr8:1020857 NA -0.36 -6.16 -0.48 9.23e-9 Schizophrenia; TGCT cis rs4499344 0.730 rs410616 chr19:33106109 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.74 0.62 1.36e-14 Mean platelet volume; TGCT cis rs7662987 0.517 rs1154405 chr4:100008750 G/A cg12011299 chr4:100065546 ADH4 0.4 4.76 0.39 5.33e-6 Smoking initiation; TGCT cis rs7914558 1.000 rs7094843 chr10:104806654 A/C cg04362960 chr10:104952993 NT5C2 0.61 5.46 0.44 2.44e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs8020441 0.945 rs72681670 chr14:51169272 C/T cg04730355 chr14:51134070 SAV1 0.75 6.28 0.49 5.1e-9 Cognitive performance; TGCT cis rs6545883 0.965 rs3771258 chr2:61764140 C/T cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs6087771 0.851 rs6087775 chr20:30325765 G/A cg13852791 chr20:30311386 BCL2L1 0.84 8.15 0.59 3.38e-13 Subcortical brain region volumes;Putamen volume; TGCT cis rs3820068 0.705 rs4645992 chr1:15849742 G/T cg05660106 chr1:15850417 CASP9 1.13 13.14 0.76 3.06e-25 Systolic blood pressure; TGCT cis rs7666738 0.830 rs7657982 chr4:99044015 G/A cg18180107 chr4:99064573 C4orf37 0.56 5.17 0.42 8.97e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.790 rs2253654 chr6:146199445 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.06 0.41 1.47e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3935685 0.874 rs55858810 chr15:78004230 G/T cg25212270 chr15:78015279 NA 0.26 5.57 0.45 1.48e-7 Intelligence (multi-trait analysis); TGCT cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg07424592 chr7:64974309 NA 1.26 8.11 0.59 4.17e-13 Diabetic kidney disease; TGCT cis rs514406 0.760 rs475969 chr1:53292607 T/A cg24675658 chr1:53192096 ZYG11B -0.89 -11.35 -0.71 6.62e-21 Monocyte count; TGCT cis rs4478858 0.735 rs11583123 chr1:31751772 T/C cg00250761 chr1:31883323 NA -0.26 -4.55 -0.38 1.28e-5 Alcohol dependence; TGCT cis rs2439831 0.850 rs28564774 chr15:44125475 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.9 6.3 0.49 4.62e-9 Lung cancer in ever smokers; TGCT cis rs4665809 0.590 rs11897162 chr2:26503654 T/C cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs4891159 0.548 rs660342 chr18:74130896 C/G cg24786174 chr18:74118243 ZNF516 0.67 13.58 0.77 2.65e-26 Longevity; TGCT cis rs1395 0.922 rs13404327 chr2:27519153 G/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.47 6.24 0.49 6.46e-9 Blood metabolite levels; TGCT cis rs12367572 1.000 rs7295923 chr12:45269284 C/T cg04608330 chr12:45269318 NELL2 -0.65 -6.63 -0.51 9.33e-10 Gut microbiome composition (summer); TGCT cis rs6484504 0.576 rs286649 chr11:31230468 C/T cg14844989 chr11:31128820 NA -0.23 -4.51 -0.38 1.47e-5 Red blood cell count; TGCT cis rs9611565 0.643 rs202634 chr22:41809623 A/G cg03806693 chr22:41940476 POLR3H 1.02 11.36 0.71 6.13e-21 Vitiligo; TGCT cis rs8177253 1.000 rs8177253 chr3:133480192 A/G cg01448562 chr3:133502909 NA 0.34 6.94 0.53 1.95e-10 Iron status biomarkers; TGCT cis rs11785400 0.793 rs10956992 chr8:143736235 A/C cg10596483 chr8:143751796 JRK 0.55 5.47 0.44 2.41e-7 Schizophrenia; TGCT cis rs67460515 0.567 rs34691229 chr3:160876897 G/T cg03342759 chr3:160939853 NMD3 -0.45 -4.53 -0.38 1.38e-5 Parkinson's disease; TGCT cis rs7924176 0.521 rs61863363 chr10:76140251 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.46 -4.48 -0.37 1.65e-5 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs6671200 0.573 rs3738171 chr1:95699594 A/G cg06440946 chr1:95699313 RWDD3 -0.65 -5.43 -0.44 2.89e-7 Stearic acid (18:0) levels; TGCT cis rs2235642 0.893 rs2076442 chr16:1591112 G/T cg10465839 chr16:1584050 IFT140;TMEM204 -0.32 -5.22 -0.42 7.17e-7 Coronary artery disease; TGCT cis rs17376456 0.877 rs9314099 chr5:93447375 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs9549260 0.755 rs58919811 chr13:41226485 A/C cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT trans rs10435719 0.509 rs13248956 chr8:11789768 C/A cg15556689 chr8:8085844 FLJ10661 0.73 6.89 0.53 2.55e-10 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs9902453 0.730 rs4583306 chr17:28538715 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.59 -5.59 -0.45 1.4e-7 Coffee consumption (cups per day); TGCT cis rs12220238 1.000 rs10824113 chr10:75969018 G/C cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2153535 0.580 rs7741456 chr6:8452424 G/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs1218582 0.596 rs11264275 chr1:154825270 G/T cg16680214 chr1:154839983 KCNN3 0.27 5.08 0.41 1.37e-6 Prostate cancer; TGCT cis rs981844 0.714 rs2405202 chr4:154705132 A/G cg14289246 chr4:154710475 SFRP2 -0.92 -8.41 -0.6 8.38e-14 Response to statins (LDL cholesterol change); TGCT cis rs4566357 0.964 rs2396443 chr2:227921208 A/G cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs3820928 1.000 rs9288617 chr2:227762815 G/C cg11843606 chr2:227700838 RHBDD1 -0.53 -4.68 -0.39 7.31e-6 Pulmonary function; TGCT cis rs9611565 0.512 rs5751147 chr22:42139054 G/A cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Vitiligo; TGCT cis rs2404602 0.647 rs11072628 chr15:77107761 C/A cg22467129 chr15:76604101 ETFA 0.48 4.7 0.39 6.7e-6 Blood metabolite levels; TGCT cis rs3099143 0.901 rs76101229 chr15:77134975 C/T cg21673338 chr15:77095150 SCAPER -0.49 -4.49 -0.37 1.59e-5 Recalcitrant atopic dermatitis; TGCT cis rs9811920 0.809 rs1387647 chr3:99826942 T/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.44 -4.81 -0.4 4.25e-6 Axial length; TGCT cis rs1843834 0.858 rs2047136 chr2:225511361 A/T cg22455342 chr2:225449267 CUL3 0.76 7.77 0.57 2.6e-12 IgE levels in asthmatics (D.p. specific); TGCT cis rs3617 0.572 rs2256332 chr3:52855865 A/G cg10802521 chr3:52805072 NEK4 0.6 6.95 0.53 1.88e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg11003573 chr3:44754125 ZNF502 -0.47 -5.44 -0.44 2.75e-7 Depressive symptoms; TGCT cis rs986417 1.000 rs1254322 chr14:60906976 G/A cg27398547 chr14:60952738 C14orf39 -1.42 -8.68 -0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs2594989 0.673 rs9855241 chr3:11602910 C/T cg00170343 chr3:11313890 ATG7 -0.69 -4.87 -0.4 3.28e-6 Circulating chemerin levels; TGCT cis rs7647973 0.593 rs9870755 chr3:49809841 A/G cg03060546 chr3:49711283 APEH 0.61 5.36 0.43 3.96e-7 Menarche (age at onset); TGCT cis rs7647973 0.626 rs1586827 chr3:49671224 T/C cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs2302464 1.000 rs16892272 chr4:15728079 C/G cg18497811 chr4:14860861 NA -0.49 -4.5 -0.37 1.57e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs854765 0.547 rs7209003 chr17:17907393 T/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.3 0.6 1.53e-13 Total body bone mineral density; TGCT cis rs6570726 0.755 rs451699 chr6:145830594 C/G cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs7613875 0.641 rs2624845 chr3:50062437 C/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.8 -8.32 -0.6 1.31e-13 Body mass index; TGCT cis rs1865760 0.865 rs1541987 chr6:25950397 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.62 -6.12 -0.48 1.12e-8 Height; TGCT cis rs7267979 1.000 rs448396 chr20:25440269 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2228479 0.764 rs7184960 chr16:89961661 C/T cg06558623 chr16:89946397 TCF25 0.5 5.92 0.47 2.91e-8 Skin colour saturation; TGCT cis rs992157 0.735 rs13393821 chr2:219076742 C/G cg00012203 chr2:219082015 ARPC2 0.81 10.19 0.68 4.34e-18 Colorectal cancer; TGCT cis rs7255045 0.752 rs11085822 chr19:12985576 A/G cg06537894 chr19:12978706 MAST1 -0.49 -4.47 -0.37 1.73e-5 Mean corpuscular volume; TGCT cis rs6460942 0.915 rs7809263 chr7:12450589 C/G cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs7666738 0.546 rs28590002 chr4:98722642 C/T cg05340658 chr4:99064831 C4orf37 0.51 5.68 0.45 9.1e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.547 rs2955380 chr17:17944349 A/G cg04398451 chr17:18023971 MYO15A 0.33 5.28 0.43 5.67e-7 Total body bone mineral density; TGCT cis rs933688 0.818 rs10052492 chr5:90759930 T/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 9.34 0.64 4.9e-16 Smoking behavior; TGCT cis rs9549260 0.753 rs9532563 chr13:41160270 T/C cg21288729 chr13:41239152 FOXO1 0.69 4.85 0.4 3.56e-6 Red blood cell count; TGCT cis rs910316 0.967 rs1071989 chr14:75564659 G/T cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs644799 0.965 rs10831425 chr11:95500628 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 11.41 0.72 4.75e-21 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7095607 0.785 rs10997959 chr10:69916909 G/C cg18986048 chr10:69913749 MYPN 0.42 4.77 0.39 5.13e-6 Lung function (FVC); TGCT cis rs7937682 0.921 rs7130753 chr11:111470567 C/T cg09085632 chr11:111637200 PPP2R1B 0.92 8.2 0.59 2.5e-13 Primary sclerosing cholangitis; TGCT cis rs6987853 0.933 rs2974352 chr8:42408483 C/T cg20539142 chr8:42623718 CHRNA6 -0.19 -4.63 -0.38 9.21e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs12136530 0.806 rs7522676 chr1:19762660 T/C cg18923740 chr1:19971790 NBL1 0.35 4.57 0.38 1.16e-5 Lead levels in blood; TGCT cis rs7845219 0.544 rs7015841 chr8:95920193 A/C cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs9993613 0.875 rs4694125 chr4:73491873 G/A cg15102770 chr4:73434591 ADAMTS3 0.51 4.7 0.39 6.79e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs9325144 0.624 rs10783333 chr12:39118931 A/T cg13010199 chr12:38710504 ALG10B 0.53 4.72 0.39 6.22e-6 Morning vs. evening chronotype; TGCT cis rs12497850 0.931 rs7621015 chr3:49016056 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.41 -0.44 3.09e-7 Parkinson's disease; TGCT cis rs2075371 0.933 rs1868785 chr7:133945855 G/C cg11752832 chr7:134001865 SLC35B4 0.7 6.0 0.47 2.04e-8 Mean platelet volume; TGCT cis rs2006933 0.959 rs16964203 chr17:26582710 A/C cg03094083 chr17:26864469 FOXN1 0.23 4.53 0.38 1.34e-5 Amyotrophic lateral sclerosis; TGCT cis rs6500602 0.627 rs9934267 chr16:4534366 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 7.4 0.55 1.78e-11 Schizophrenia; TGCT cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.7e-7 Developmental language disorder (linguistic errors); TGCT cis rs593982 0.925 rs603509 chr11:65507605 C/T cg08755490 chr11:65554678 OVOL1 -1.19 -11.29 -0.71 9.28e-21 Atopic dermatitis; TGCT cis rs4665809 0.590 rs35727620 chr2:26458364 G/A cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs34734847 1.000 rs35360964 chr12:121156290 T/C cg21892295 chr12:121157589 UNC119B -0.23 -5.63 -0.45 1.14e-7 Mean corpuscular volume; TGCT cis rs11809207 0.723 rs57653638 chr1:26524401 A/G cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs11098499 0.908 rs9995234 chr4:120321827 A/G cg09307838 chr4:120376055 NA 0.67 6.39 0.5 3.05e-9 Corneal astigmatism; TGCT cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.2 -0.42 7.9e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs5769765 0.773 rs138834 chr22:50180497 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.12 -9.53 -0.65 1.73e-16 Schizophrenia; TGCT cis rs4234284 0.556 rs9968173 chr3:126965437 G/A cg26312807 chr3:127057048 NA -0.5 -4.6 -0.38 1.03e-5 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs425277 0.606 rs3128339 chr1:2046938 G/T cg24578937 chr1:2090814 PRKCZ -0.25 -5.99 -0.47 2.14e-8 Height; TGCT cis rs62244186 0.659 rs9850129 chr3:44532047 C/T cg10263370 chr3:44754102 ZNF502 -0.4 -4.8 -0.4 4.4e-6 Depressive symptoms; TGCT cis rs2980439 0.525 rs2945238 chr8:8170136 A/C cg06636001 chr8:8085503 FLJ10661 0.72 6.33 0.49 4.14e-9 Neuroticism; TGCT cis rs9913156 0.793 rs72835642 chr17:4573407 T/C cg00122941 chr17:4613640 ARRB2 0.88 7.51 0.56 1.03e-11 Lymphocyte counts; TGCT cis rs854765 0.927 rs12943914 chr17:17980671 A/G cg04398451 chr17:18023971 MYO15A -0.3 -4.72 -0.39 6.28e-6 Total body bone mineral density; TGCT cis rs3806843 0.576 rs246045 chr5:140329884 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7707921 0.752 rs2897554 chr5:81276241 C/T cg15871215 chr5:81402204 ATG10 0.29 5.07 0.41 1.39e-6 Breast cancer; TGCT trans rs4262150 0.544 rs17549488 chr5:151917354 C/A cg26032021 chr14:54804413 NA 0.39 6.64 0.51 8.72e-10 Bipolar disorder and schizophrenia; TGCT cis rs2017387 0.572 rs157546 chr19:50525126 G/A cg19230443 chr19:49950584 PIH1D1 -0.29 -4.69 -0.39 7.22e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs17384381 0.859 rs12724823 chr1:85906385 G/T cg16011679 chr1:85725395 C1orf52 0.84 6.87 0.52 2.83e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6450176 1.000 rs6886510 chr5:53303127 A/G ch.5.1024479R chr5:53302184 ARL15 0.55 5.37 0.43 3.68e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs10782582 0.609 rs5745469 chr1:76347394 G/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs9534288 0.797 rs2404728 chr13:46581862 T/C cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs858239 0.670 rs6967526 chr7:23159241 C/A cg05602783 chr7:23145260 KLHL7 -0.59 -4.94 -0.41 2.42e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4689592 0.619 rs3796908 chr4:7061378 G/A cg26116260 chr4:7069785 GRPEL1 1.0 9.12 0.63 1.72e-15 Monocyte percentage of white cells; TGCT cis rs9419702 0.568 rs10782366 chr10:133557866 G/A cg20568497 chr10:133558893 NA 0.47 5.04 0.41 1.63e-6 Survival in rectal cancer; TGCT cis rs6430585 0.697 rs1050115 chr2:136511817 A/G cg07169764 chr2:136633963 MCM6 1.2 11.43 0.72 4.14e-21 Corneal structure; TGCT cis rs8017423 0.866 rs10184 chr14:90744672 G/A cg04374321 chr14:90722782 PSMC1 -0.73 -6.84 -0.52 3.15e-10 Mortality in heart failure; TGCT cis rs17387100 0.901 rs55808189 chr4:15983246 T/C cg14577840 chr4:16257979 FLJ39653 0.5 4.85 0.4 3.56e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs916888 0.773 rs538628 chr17:44787313 G/C cg15921436 chr17:44337874 NA 0.59 8.18 0.59 2.85e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9467711 0.790 rs13198716 chr6:26582035 A/G cg12315302 chr6:26189340 HIST1H4D -0.99 -4.44 -0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2836633 1.000 rs2836631 chr21:40065906 G/T cg05519781 chr21:40033154 ERG -0.55 -5.44 -0.44 2.74e-7 Coronary artery disease; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg01585852 chr22:24235823 MIF -0.22 -4.68 -0.39 7.49e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1577917 0.958 rs34230196 chr6:86526022 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs7772486 0.875 rs864390 chr6:146315035 G/T cg23711669 chr6:146136114 FBXO30 0.82 8.84 0.62 7.71e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg19318889 chr4:1322082 MAEA 0.27 6.56 0.51 1.3e-9 Longevity; TGCT cis rs9916302 0.706 rs801418 chr17:37457982 G/C cg07936489 chr17:37558343 FBXL20 0.84 6.23 0.49 6.68e-9 Glomerular filtration rate (creatinine); TGCT cis rs7552404 0.924 rs1251075 chr1:76190569 C/G cg22875332 chr1:76189707 ACADM 0.73 9.16 0.64 1.34e-15 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs6561151 0.957 rs7995004 chr13:44478820 C/T cg12856521 chr11:46389249 DGKZ 0.69 7.75 0.57 2.8e-12 Crohn's disease; TGCT cis rs854624 0.892 rs1608206 chr17:34336836 G/A cg02022384 chr17:34097390 MMP28 0.49 4.55 0.38 1.28e-5 Blood protein levels; TGCT cis rs9902453 0.967 rs3813034 chr17:28524804 A/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs7267979 0.586 rs1007707 chr20:25190598 A/G cg03522245 chr20:25566470 NINL 0.5 5.24 0.43 6.66e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3751972 0.911 rs1157502 chr17:26250109 G/T cg02948944 chr17:26242737 NA 0.51 7.15 0.54 6.43e-11 Fractional exhaled nitric oxide (childhood); TGCT cis rs9443645 0.901 rs9343856 chr6:79678211 G/A cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.3e-7 Intelligence (multi-trait analysis); TGCT cis rs3752962 0.569 rs3803806 chr17:1940713 T/C cg24156229 chr17:1948635 NA -0.37 -7.07 -0.54 9.83e-11 Itch intensity from mosquito bite; TGCT cis rs763121 0.853 rs6001175 chr22:39018334 T/C cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs651907 0.535 rs13065944 chr3:101473088 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.87 10.21 0.68 3.89e-18 Colorectal cancer; TGCT cis rs6690583 0.623 rs2083283 chr1:85439996 C/A cg20280350 chr1:85513789 MCOLN3 -0.67 -4.5 -0.37 1.52e-5 Serum sulfate level; TGCT cis rs7089973 0.604 rs7895830 chr10:116625776 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.61 0.45 1.26e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs9517320 0.534 rs4771306 chr13:99143661 T/C cg07423050 chr13:99094983 FARP1 -0.29 -5.74 -0.46 6.86e-8 Longevity; TGCT cis rs6746896 1.000 rs4619651 chr2:97416153 G/A cg26085987 chr2:97230376 NA 0.19 4.66 0.39 8.17e-6 Bipolar disorder; TGCT cis rs9929218 0.953 rs3114411 chr16:68734591 G/T cg01251360 chr16:68772225 CDH1 -0.31 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs62244186 0.659 rs4682745 chr3:44508967 T/C cg10263370 chr3:44754102 ZNF502 -0.39 -4.8 -0.4 4.41e-6 Depressive symptoms; TGCT cis rs2692947 0.727 rs893173 chr2:96789787 T/C cg23100626 chr2:96804247 ASTL 0.43 5.24 0.43 6.58e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7513165 0.611 rs34729972 chr1:204159178 A/G cg12731349 chr1:204159619 KISS1 0.54 5.87 0.47 3.77e-8 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs1008375 0.898 rs4698623 chr4:17594702 T/C cg18681998 chr4:17616180 MED28 1.0 10.06 0.67 8.8e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7017914 0.967 rs13254801 chr8:71688984 T/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs4642101 0.855 rs9836128 chr3:12845426 G/C cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg22997113 chr7:27170241 HOXA4 -0.44 -4.6 -0.38 1.05e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7100689 0.646 rs12253992 chr10:82158710 G/A cg01528321 chr10:82214614 TSPAN14 0.73 7.73 0.57 3.25e-12 Post bronchodilator FEV1; TGCT cis rs4711350 1.000 rs2395401 chr6:33759471 T/C cg18005901 chr6:33739558 LEMD2 -0.55 -5.89 -0.47 3.38e-8 Schizophrenia; TGCT cis rs240764 0.658 rs4840148 chr6:101182500 G/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs7267979 0.789 rs4815429 chr20:25521611 T/C cg14121845 chr20:25566513 NINL -0.46 -4.76 -0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9399135 0.967 rs4451151 chr6:135310546 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs2456568 0.771 rs2102333 chr11:93634749 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.07e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1799949 1.000 rs4793192 chr17:41204390 T/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.05 0.41 1.51e-6 Menopause (age at onset); TGCT cis rs1971762 0.504 rs1843318 chr12:53958077 C/T cg16917193 chr12:54089295 NA 1.02 10.34 0.68 1.87e-18 Height; TGCT cis rs2153535 0.601 rs7741024 chr6:8530313 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs1129187 0.805 rs1053538 chr6:42903763 C/G cg02353165 chr6:42928485 GNMT 0.69 6.07 0.48 1.43e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4689592 0.513 rs2358718 chr4:7068743 A/C cg26116260 chr4:7069785 GRPEL1 -1.07 -10.78 -0.7 1.56e-19 Monocyte percentage of white cells; TGCT cis rs8020441 0.541 rs67447434 chr14:51156101 G/A cg04730355 chr14:51134070 SAV1 1.23 9.65 0.66 8.78e-17 Cognitive performance; TGCT cis rs3771570 0.901 rs4675969 chr2:242217627 C/T cg21155796 chr2:242212141 HDLBP 0.85 6.47 0.5 2.05e-9 Prostate cancer; TGCT cis rs66561647 0.563 rs4733580 chr8:128932677 G/A cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.6 0.38 1.01e-5 Hemoglobin concentration; TGCT cis rs3540 1.000 rs7173724 chr15:91036855 A/G cg22089800 chr15:90895588 ZNF774 0.78 7.92 0.58 1.15e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9926296 0.712 rs2434872 chr16:89716915 C/G cg27121462 chr16:89883253 FANCA -0.55 -5.0 -0.41 1.93e-6 Vitiligo; TGCT cis rs10875746 0.903 rs10875735 chr12:48463806 T/C cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs78456975 0.527 rs11884165 chr2:1561052 A/G cg12573674 chr2:1569213 NA -0.45 -4.76 -0.39 5.37e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs55794721 0.543 rs1293260 chr1:25709104 C/G cg09222892 chr1:25734099 RHCE -0.42 -6.69 -0.51 6.94e-10 Plateletcrit;Mean corpuscular volume; TGCT cis rs2836974 0.897 rs7280375 chr21:40552408 C/T cg17971929 chr21:40555470 PSMG1 -0.92 -8.25 -0.6 1.98e-13 Cognitive function; TGCT cis rs10791323 0.628 rs2853117 chr11:133705266 T/G cg15485101 chr11:133734466 NA 0.4 5.08 0.42 1.34e-6 Childhood ear infection; TGCT cis rs3809566 0.654 rs4775606 chr15:63327605 A/G cg08198488 chr15:63333792 TPM1 -0.35 -5.37 -0.43 3.81e-7 Platelet count; TGCT trans rs6089829 0.890 rs6062775 chr20:61663650 T/C cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2354432 0.556 rs2883319 chr1:146838177 A/G cg25205988 chr1:146714368 CHD1L -1.35 -5.81 -0.46 4.96e-8 Mitochondrial DNA levels; TGCT cis rs7223966 1.000 rs1877316 chr17:61766880 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.61 0.38 1e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9916302 0.861 rs2338801 chr17:37490780 G/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs11250097 0.506 rs13281992 chr8:11309294 C/T cg01383082 chr8:11323474 FAM167A 0.33 4.92 0.4 2.73e-6 Neuroticism; TGCT cis rs11676348 0.935 rs2230054 chr2:219000310 C/T cg00012203 chr2:219082015 ARPC2 -0.5 -4.45 -0.37 1.88e-5 Ulcerative colitis; TGCT cis rs9611565 0.879 rs5758307 chr22:41750219 A/G cg06481639 chr22:41940642 POLR3H -0.57 -4.93 -0.4 2.61e-6 Vitiligo; TGCT cis rs7809950 0.817 rs2237671 chr7:107131528 A/T cg23024343 chr7:107201750 COG5 -0.45 -6.69 -0.51 6.9e-10 Coronary artery disease; TGCT cis rs1729951 0.575 rs1682357 chr3:136692009 G/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs2836950 0.502 rs2150411 chr21:40574552 G/T cg06238570 chr21:40685208 BRWD1 -0.62 -6.42 -0.5 2.58e-9 Menarche (age at onset); TGCT cis rs137699 1.000 rs137699 chr22:39748854 A/G cg11247378 chr22:39784982 NA -0.44 -4.71 -0.39 6.48e-6 IgG glycosylation; TGCT cis rs4689388 0.824 rs4467645 chr4:6294305 C/T cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9916302 0.904 rs679995 chr17:37441679 A/T cg07936489 chr17:37558343 FBXL20 0.6 4.75 0.39 5.45e-6 Glomerular filtration rate (creatinine); TGCT cis rs447921 0.773 rs11077821 chr17:74455579 C/T cg09812376 chr17:74270190 QRICH2 -0.45 -4.5 -0.37 1.53e-5 Mitochondrial DNA levels; TGCT cis rs7107174 0.681 rs881337 chr11:78128335 G/C cg12700464 chr11:78128424 GAB2 -0.67 -4.46 -0.37 1.83e-5 Testicular germ cell tumor; TGCT cis rs9325144 0.556 rs34565156 chr12:39028239 G/A cg10518543 chr12:38710700 ALG10B -0.51 -4.84 -0.4 3.83e-6 Morning vs. evening chronotype; TGCT cis rs10791323 0.569 rs10791335 chr11:133739571 A/T cg03690763 chr11:133734501 NA -0.28 -4.76 -0.39 5.32e-6 Childhood ear infection; TGCT cis rs6582630 0.519 rs12582285 chr12:38298753 C/T cg26384229 chr12:38710491 ALG10B 0.8 7.04 0.53 1.17e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs2228638 0.816 rs2269094 chr10:33528486 T/C cg08604594 chr10:33798231 NA -0.38 -4.81 -0.4 4.23e-6 Tetralogy of Fallot; TGCT cis rs288326 0.561 rs17703779 chr2:183895919 C/T cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs853679 0.527 rs213228 chr6:28331252 A/C cg18815343 chr6:28367644 ZSCAN12 -0.5 -5.01 -0.41 1.81e-6 Depression; TGCT cis rs9372498 0.536 rs72952733 chr6:118834452 A/G cg07617317 chr6:118971624 C6orf204 0.51 5.42 0.44 3e-7 Diastolic blood pressure; TGCT cis rs3771570 0.901 rs35496488 chr2:242434316 G/A cg21155796 chr2:242212141 HDLBP 0.92 6.63 0.51 9.25e-10 Prostate cancer; TGCT cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg21724239 chr8:58056113 NA 0.39 4.59 0.38 1.07e-5 Developmental language disorder (linguistic errors); TGCT cis rs4820539 1.000 rs885964 chr22:23461003 G/C cg21100191 chr22:23484243 RTDR1 0.91 10.67 0.69 2.9e-19 Bone mineral density; TGCT cis rs858239 0.537 rs10279691 chr7:23228387 A/G cg05602783 chr7:23145260 KLHL7 -0.71 -5.5 -0.44 2.12e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2120019 1.000 rs7162900 chr15:75368017 T/C cg17294928 chr15:75287854 SCAMP5 -0.85 -6.5 -0.5 1.78e-9 Blood trace element (Zn levels); TGCT cis rs2797160 1.000 rs1739348 chr6:126014573 T/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs2760061 0.626 rs591582 chr1:228117360 C/A cg18477163 chr1:228402036 OBSCN -0.32 -6.35 -0.5 3.71e-9 Diastolic blood pressure; TGCT cis rs6088580 0.634 rs6059779 chr20:32950325 C/T cg06115741 chr20:33292138 TP53INP2 -0.55 -4.8 -0.4 4.5e-6 Glomerular filtration rate (creatinine); TGCT cis rs739496 0.579 rs12319315 chr12:112341019 A/C cg10833066 chr12:111807467 FAM109A 0.38 4.94 0.41 2.51e-6 Platelet count; TGCT cis rs1519814 0.616 rs28885745 chr8:121012458 T/C cg22335954 chr8:121166405 COL14A1 -0.36 -4.52 -0.38 1.44e-5 Breast cancer; TGCT trans rs8073060 0.586 rs225256 chr17:33955756 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs12497850 1.000 rs6788650 chr3:48749543 T/C cg07636037 chr3:49044803 WDR6 0.92 10.34 0.68 1.91e-18 Parkinson's disease; TGCT cis rs9322193 0.884 rs11155675 chr6:150064019 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.46e-5 Lung cancer; TGCT cis rs9291683 0.679 rs3756225 chr4:10094133 G/C cg11266682 chr4:10021025 SLC2A9 -0.51 -6.16 -0.48 9.39e-9 Bone mineral density; TGCT cis rs950776 0.518 rs4886572 chr15:78837452 A/G cg06917634 chr15:78832804 PSMA4 -0.93 -9.08 -0.63 2.07e-15 Sudden cardiac arrest; TGCT cis rs2677744 0.719 rs2106673 chr15:91452595 A/G cg22570213 chr15:91497863 RCCD1 0.39 4.52 0.38 1.41e-5 Attention deficit hyperactivity disorder; TGCT cis rs1862618 0.853 rs2548664 chr5:56133555 G/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs478607 1.000 rs478607 chr11:64478063 A/G cg19395706 chr11:64412079 NRXN2 0.47 5.08 0.41 1.35e-6 Urate levels; TGCT trans rs3780486 0.505 rs10813958 chr9:33165985 A/G cg04842962 chr6:43655489 MRPS18A 0.81 8.89 0.62 6.14e-15 IgG glycosylation; TGCT cis rs11030122 0.660 rs10835248 chr11:3910328 G/A cg18678763 chr11:4115507 RRM1 -0.35 -4.45 -0.37 1.85e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs10488031 0.557 rs71539815 chr7:37111356 C/T cg06458904 chr7:36312573 EEPD1 0.58 4.8 0.4 4.49e-6 QT interval; TGCT cis rs875971 1.000 rs6460295 chr7:65882728 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.79e-7 Aortic root size; TGCT cis rs7552404 0.731 rs5745458 chr1:76345429 G/A cg03433033 chr1:76189801 ACADM -0.76 -7.76 -0.57 2.66e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg20203395 chr5:56204925 C5orf35 -0.58 -4.94 -0.41 2.45e-6 Initial pursuit acceleration; TGCT cis rs3733585 0.699 rs4621431 chr4:9947590 C/T cg11266682 chr4:10021025 SLC2A9 -0.62 -8.11 -0.59 4.09e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9611519 0.780 rs2235849 chr22:41653540 T/G cg13695892 chr22:41940480 POLR3H -0.62 -5.83 -0.46 4.54e-8 Neuroticism; TGCT cis rs7000551 0.715 rs7828610 chr8:22307326 C/T cg12081754 chr8:22256438 SLC39A14 0.33 5.48 0.44 2.26e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7178572 0.568 rs8037561 chr15:77680462 A/G cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg03806693 chr22:41940476 POLR3H -1.13 -12.32 -0.74 2.89e-23 Vitiligo; TGCT cis rs4927850 0.666 rs4927853 chr3:195752053 G/C cg12923728 chr3:195709715 SDHAP1 -0.37 -6.5 -0.5 1.78e-9 Pancreatic cancer; TGCT cis rs4711350 0.862 rs688209 chr6:33700376 G/T cg18005901 chr6:33739558 LEMD2 -0.45 -4.81 -0.4 4.3e-6 Schizophrenia; TGCT cis rs78707713 0.560 rs61848397 chr10:71225584 C/A cg14388049 chr10:71211838 TSPAN15 -0.39 -4.68 -0.39 7.52e-6 Venous thromboembolism; TGCT cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg10560079 chr2:191398806 TMEM194B 0.37 5.33 0.43 4.5e-7 Pulse pressure; TGCT cis rs1499614 1.000 rs2707828 chr7:66171377 G/A cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT trans rs854624 0.681 rs79694259 chr17:34328890 C/T cg25044186 chr6:170494475 NA 0.75 6.73 0.52 5.7e-10 Blood protein levels; TGCT cis rs317689 0.718 rs645026 chr12:69757931 G/A cg14784868 chr12:69753453 YEATS4 0.55 4.68 0.39 7.24e-6 Response to diuretic therapy; TGCT cis rs7843479 0.965 rs11785657 chr8:21859485 G/A cg17168535 chr8:21777572 XPO7 0.64 5.82 0.46 4.81e-8 Mean corpuscular volume; TGCT cis rs921968 0.643 rs484085 chr2:219396684 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs7523273 0.505 rs35438924 chr1:207881489 T/G cg22525895 chr1:207977042 MIR29B2 0.29 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs17293817 0.650 rs12778422 chr10:1413776 A/G cg05483559 chr10:1416597 ADARB2 0.25 4.45 0.37 1.89e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs3772130 0.962 rs6791046 chr3:121394707 A/G cg01951420 chr3:121553821 IQCB1;EAF2 0.55 4.98 0.41 2.09e-6 Cognitive performance; TGCT cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs1372520 0.684 rs10008964 chr4:90744721 G/A cg15133208 chr4:90757351 SNCA -0.49 -5.69 -0.45 8.67e-8 Neuroticism; TGCT cis rs4149423 1.000 rs4149423 chr2:108916044 A/G cg25838818 chr2:108905173 SULT1C2 -0.42 -7.16 -0.54 6.16e-11 Lobe size; TGCT cis rs6840360 0.642 rs2724567 chr4:152351160 C/T cg17479576 chr4:152424074 FAM160A1 0.57 6.07 0.48 1.46e-8 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg16680214 chr1:154839983 KCNN3 -0.36 -7.33 -0.55 2.59e-11 Prostate cancer; TGCT cis rs4689592 0.554 rs3822270 chr4:7069804 C/A cg02503808 chr4:7069936 GRPEL1 1.0 9.53 0.65 1.77e-16 Monocyte percentage of white cells; TGCT cis rs9733 0.596 rs7549795 chr1:150656873 G/A cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs7147624 1.000 rs2411354 chr14:66062132 T/C cg03016385 chr14:66212404 NA -0.49 -7.08 -0.54 9.33e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs7772486 0.806 rs2253648 chr6:146199296 G/A cg05347473 chr6:146136440 FBXO30 0.55 5.21 0.42 7.53e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs7824557 0.524 rs7835318 chr8:10953874 G/A cg06636001 chr8:8085503 FLJ10661 -0.77 -7.05 -0.53 1.11e-10 Retinal vascular caliber; TGCT cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg03609598 chr5:56110824 MAP3K1 -0.56 -4.57 -0.38 1.14e-5 Initial pursuit acceleration; TGCT cis rs7940866 0.834 rs7939417 chr11:130853832 T/A cg05962950 chr11:130786565 SNX19 0.71 6.9 0.53 2.33e-10 Schizophrenia; TGCT cis rs1568889 1.000 rs11603799 chr11:28196488 T/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 8.17 0.59 3.04e-13 Bipolar disorder; TGCT cis rs1453308 0.938 rs1453307 chr2:237186698 G/A cg19324714 chr2:237145437 ASB18 0.57 5.08 0.41 1.37e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs2153535 0.580 rs5001322 chr6:8451608 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs68170813 0.559 rs77829121 chr7:106968470 A/G cg02696742 chr7:106810147 HBP1 -0.7 -5.85 -0.47 4.03e-8 Coronary artery disease; TGCT cis rs8016982 0.963 rs2099108 chr14:81675420 C/G cg01989461 chr14:81687754 GTF2A1 0.62 5.27 0.43 5.83e-7 Schizophrenia; TGCT cis rs2836974 0.800 rs73221174 chr21:40540939 T/C cg17971929 chr21:40555470 PSMG1 0.93 8.54 0.61 3.97e-14 Cognitive function; TGCT cis rs2820315 0.964 rs2820311 chr1:201841476 A/G cg12730843 chr1:201915899 LMOD1 -0.26 -4.71 -0.39 6.53e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs36051895 0.589 rs16922786 chr9:5200714 A/G cg02405213 chr9:5042618 JAK2 -0.73 -9.54 -0.65 1.67e-16 Pediatric autoimmune diseases; TGCT cis rs6089584 0.893 rs6089305 chr20:60571817 T/C cg13770153 chr20:60521292 NA -0.54 -7.28 -0.55 3.32e-11 Body mass index; TGCT cis rs10504229 0.728 rs17804720 chr8:58154565 T/C cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs1215050 0.791 rs260890 chr4:98741698 A/G cg05340658 chr4:99064831 C4orf37 0.42 5.14 0.42 1.04e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7647973 1.000 rs3905330 chr3:49550774 A/G cg07636037 chr3:49044803 WDR6 0.6 4.96 0.41 2.22e-6 Menarche (age at onset); TGCT cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg24829409 chr8:58192753 C8orf71 -0.54 -4.69 -0.39 7.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.62e-9 Blood metabolite levels; TGCT cis rs1670533 1.000 rs4690215 chr4:1054619 G/C cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs79976124 0.879 rs12214948 chr6:66633603 G/A cg07460842 chr6:66804631 NA 0.57 5.18 0.42 8.76e-7 Type 2 diabetes; TGCT cis rs2836974 0.965 rs7354783 chr21:40652992 G/A cg17971929 chr21:40555470 PSMG1 0.97 9.52 0.65 1.86e-16 Cognitive function; TGCT cis rs9457247 1.000 rs1819333 chr6:167373547 G/T cg23791538 chr6:167370224 RNASET2 -0.51 -5.12 -0.42 1.15e-6 Crohn's disease; TGCT cis rs1468333 0.724 rs7726580 chr5:137608666 A/G cg27119451 chr5:137514611 BRD8;KIF20A -0.46 -4.45 -0.37 1.91e-5 Resting heart rate; TGCT cis rs11894932 0.848 rs6711099 chr2:99232873 C/T cg27446566 chr2:99952965 EIF5B;TXNDC9 0.67 4.57 0.38 1.16e-5 Left ventricular obstructive tract defect (inherited effect); TGCT cis rs826838 1.000 rs7299124 chr12:39002661 T/C cg26384229 chr12:38710491 ALG10B 1.04 10.21 0.68 4.01e-18 Heart rate; TGCT cis rs4722166 0.597 rs2069845 chr7:22770149 G/A cg26061582 chr7:22766209 IL6 0.58 7.53 0.56 8.97e-12 Lung cancer; TGCT cis rs1865760 0.613 rs2071300 chr6:25914572 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.62 6.63 0.51 9.14e-10 Height; TGCT cis rs514406 0.607 rs6696940 chr1:53203427 C/T cg22166914 chr1:53195759 ZYG11B -0.49 -9.15 -0.63 1.43e-15 Monocyte count; TGCT cis rs6951245 1.000 rs79683221 chr7:1096139 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs561341 1.000 rs510264 chr17:30323414 A/G cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs707040 1.000 rs707040 chr2:155226677 C/T cg18104148 chr2:154337490 NA 0.18 4.44 0.37 1.95e-5 Sudden cardiac arrest; TGCT cis rs11650494 0.908 rs9907478 chr17:47395729 C/T cg08112188 chr17:47440006 ZNF652 0.98 5.33 0.43 4.57e-7 Prostate cancer; TGCT cis rs11190604 0.767 rs77769532 chr10:102193646 T/C cg16342193 chr10:102329863 NA -0.41 -5.2 -0.42 8.01e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7819412 0.745 rs28591576 chr8:11080675 C/T cg21775007 chr8:11205619 TDH -0.56 -5.15 -0.42 9.93e-7 Triglycerides; TGCT cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs2013441 0.711 rs1682297 chr17:20384920 C/T cg23224458 chr17:20280056 CCDC144C 0.38 4.66 0.39 8.02e-6 Obesity-related traits; TGCT cis rs12765878 1.000 rs7100920 chr10:105640978 A/G cg11005552 chr10:105648138 OBFC1 -0.4 -6.95 -0.53 1.88e-10 Coronary artery disease; TGCT cis rs56235845 0.694 rs6876677 chr5:176755342 T/C cg06060754 chr5:176797920 RGS14 0.39 6.22 0.49 7.05e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs6495122 0.651 rs11636952 chr15:75114322 T/C cg10253484 chr15:75165896 SCAMP2 -0.66 -5.62 -0.45 1.19e-7 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs6545883 0.929 rs1209434 chr2:61672958 G/A cg15711740 chr2:61764176 XPO1 -0.51 -4.57 -0.38 1.15e-5 Tuberculosis; TGCT cis rs947211 0.846 rs708726 chr1:205762139 G/T cg14893161 chr1:205819251 PM20D1 -0.47 -5.17 -0.42 9.03e-7 Parkinson's disease; TGCT cis rs6988636 1.000 rs4282551 chr8:124185916 G/A cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs17387100 1.000 rs73230286 chr4:15993149 A/C cg13480465 chr4:16795757 LDB2 -0.41 -4.66 -0.39 8e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs73198271 0.729 rs11786474 chr8:8605492 T/C ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.7 -0.39 6.66e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs546131 0.928 rs552171 chr11:34830709 G/T cg11058730 chr11:34937778 PDHX;APIP 0.58 5.06 0.41 1.46e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7267979 1.000 rs6050629 chr20:25430680 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9303401 0.659 rs17822807 chr17:56687190 A/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs9217 0.841 rs56226499 chr17:7398223 C/T cg17892169 chr17:7452644 TNFSF12;TNFSF12-TNFSF13 -0.23 -4.44 -0.37 1.99e-5 Height; TGCT cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.46 4.52 0.38 1.4e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1629083 0.905 rs17121882 chr11:118081468 C/T cg16594165 chr11:118135105 MPZL2 -0.33 -4.59 -0.38 1.09e-5 Lung cancer; TGCT cis rs860554 0.640 rs2268150 chr1:201257838 G/A cg01022117 chr1:201258280 PKP1 -0.36 -6.91 -0.53 2.27e-10 Panic disorder; TGCT cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg00684032 chr4:1343700 KIAA1530 0.23 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs7017914 0.967 rs10448014 chr8:71688165 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg20637647 chr7:64974828 NA 0.86 4.93 0.4 2.58e-6 Diabetic kidney disease; TGCT cis rs3096299 0.658 rs34590044 chr16:89543157 A/C cg08392591 chr16:89556376 ANKRD11 0.56 5.33 0.43 4.39e-7 Multiple myeloma (IgH translocation); TGCT cis rs57994353 0.760 rs4413892 chr9:139330158 G/A cg13741927 chr9:139327495 INPP5E -0.27 -6.41 -0.5 2.72e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9916302 0.851 rs11078907 chr17:37662954 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs12497850 0.863 rs4974084 chr3:48939080 G/A cg07636037 chr3:49044803 WDR6 0.95 9.97 0.67 1.53e-17 Parkinson's disease; TGCT cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs9916302 0.904 rs602282 chr17:37433021 C/T cg15445000 chr17:37608096 MED1 0.33 4.81 0.4 4.3e-6 Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.897 rs2584635 chr17:61865934 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.63 0.38 9.2e-6 Prudent dietary pattern; TGCT cis rs35883536 0.967 rs2783689 chr1:101092411 C/G cg06223162 chr1:101003688 GPR88 -0.3 -4.96 -0.41 2.28e-6 Monocyte count; TGCT cis rs28386778 0.700 rs11079515 chr17:62005645 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.5 -4.8 -0.4 4.55e-6 Prudent dietary pattern; TGCT cis rs17221829 0.733 rs12281810 chr11:89409595 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 1.96e-5 Anxiety in major depressive disorder; TGCT cis rs3784262 0.669 rs4646609 chr15:58274989 G/A cg12031962 chr15:58353849 ALDH1A2 -0.41 -5.82 -0.46 4.72e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs3749237 1.000 rs11710675 chr3:49751900 C/A cg07636037 chr3:49044803 WDR6 0.63 5.5 0.44 2.08e-7 Resting heart rate; TGCT cis rs2268241 0.938 rs9974603 chr21:34776300 C/A cg14850771 chr21:34775459 IFNGR2 0.63 5.34 0.43 4.3e-7 Obesity-related traits; TGCT cis rs2836633 0.929 rs11702165 chr21:40035313 C/T cg05519781 chr21:40033154 ERG 0.7 6.95 0.53 1.86e-10 Coronary artery disease; TGCT cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs9303401 0.614 rs2007993 chr17:56590643 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs1018836 0.786 rs7016220 chr8:91606848 A/G cg16814680 chr8:91681699 NA -0.71 -7.25 -0.55 3.89e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs3820068 0.608 rs10927831 chr1:16028373 T/G cg17385448 chr1:15911702 AGMAT 0.34 4.78 0.39 4.97e-6 Systolic blood pressure; TGCT cis rs2439831 0.867 rs2412779 chr15:43655927 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs1371867 0.846 rs1788199 chr8:101292854 A/G cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs17293817 0.588 rs17221652 chr10:1416472 C/G cg05336292 chr10:466338 DIP2C -0.19 -4.46 -0.37 1.83e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1799949 1.000 rs11652332 chr17:41295489 G/A cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.79e-10 Menopause (age at onset); TGCT trans rs2727020 0.617 rs7102702 chr11:49401125 T/G cg15704280 chr7:45808275 SEPT13 -0.65 -6.71 -0.52 6.25e-10 Coronary artery disease; TGCT cis rs67311347 0.544 rs6769627 chr3:40327845 G/A cg13683864 chr3:40499215 RPL14 -0.77 -7.15 -0.54 6.65e-11 Renal cell carcinoma; TGCT cis rs9457247 1.000 rs408918 chr6:167399282 G/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.92 -0.4 2.7e-6 Crohn's disease; TGCT cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7267979 1.000 rs2387881 chr20:25378172 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7258465 1.000 rs3810429 chr19:18543270 G/T cg06462663 chr19:18546047 ISYNA1 0.2 4.54 0.38 1.33e-5 Breast cancer; TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg26354017 chr1:205819088 PM20D1 0.58 7.1 0.54 8.46e-11 Menarche (age at onset); TGCT cis rs9457247 0.967 rs1590257 chr6:167377782 G/T cg23791538 chr6:167370224 RNASET2 0.5 4.98 0.41 2.06e-6 Crohn's disease; TGCT cis rs595982 0.527 rs55670257 chr19:49382654 G/A cg21252483 chr19:49399788 TULP2 -0.46 -7.03 -0.53 1.25e-10 Red cell distribution width; TGCT cis rs6582630 0.538 rs7971292 chr12:38498151 A/G cg26384229 chr12:38710491 ALG10B -0.55 -4.91 -0.4 2.86e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs1008375 0.932 rs11941874 chr4:17666416 C/T cg16339924 chr4:17578868 LAP3 -0.6 -4.91 -0.4 2.76e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9733 0.596 rs11204687 chr1:150629880 C/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs10504229 0.769 rs17804383 chr8:58151830 A/G cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs319204 1.000 rs319232 chr5:146241598 C/T cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs11577318 0.853 rs11247913 chr1:26648551 G/C cg12733254 chr1:26682999 NA -0.21 -4.51 -0.38 1.46e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs7666738 0.830 rs17484890 chr4:99013778 T/C cg17366294 chr4:99064904 C4orf37 0.67 6.97 0.53 1.69e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7731657 0.537 rs10073388 chr5:130188080 C/T cg08523029 chr5:130500466 HINT1 -0.55 -4.57 -0.38 1.15e-5 Fasting plasma glucose; TGCT cis rs3858526 0.920 rs11039548 chr11:5930283 G/A cg13902645 chr11:5959945 NA -0.44 -4.8 -0.4 4.54e-6 DNA methylation (variation); TGCT cis rs67311347 1.000 rs12634013 chr3:40452388 T/C cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs8111998 0.826 rs4932774 chr19:22766593 G/T cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs4629710 0.592 rs13206776 chr6:131576679 T/G cg12606694 chr6:131520996 AKAP7 0.4 4.74 0.39 5.82e-6 Multiple myeloma (IgH translocation); TGCT cis rs986417 1.000 rs1254254 chr14:60831146 G/A cg27398547 chr14:60952738 C14orf39 -1.36 -8.75 -0.62 1.28e-14 Gut microbiota (bacterial taxa); TGCT cis rs4665809 1.000 rs7588802 chr2:26277789 A/G cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.36e-9 Gut microbiome composition (summer); TGCT cis rs4919044 0.808 rs835277 chr10:94809677 T/C cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs270601 0.690 rs162907 chr5:131580152 A/G cg24060327 chr5:131705240 SLC22A5 0.6 6.19 0.49 7.99e-9 Acylcarnitine levels; TGCT cis rs79149102 0.579 rs12591175 chr15:75356073 C/T cg09165964 chr15:75287851 SCAMP5 -1.15 -6.31 -0.49 4.4e-9 Lung cancer; TGCT cis rs7666738 0.753 rs7698541 chr4:98986351 T/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.882 rs2030564 chr3:10039044 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.68 -0.51 7.22e-10 Alzheimer's disease; TGCT cis rs17102423 0.594 rs1256417 chr14:65563678 C/T cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.57e-9 Obesity-related traits; TGCT cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs6831352 0.760 rs1311616 chr4:100012303 T/G cg12011299 chr4:100065546 ADH4 0.4 4.76 0.39 5.33e-6 Alcohol dependence; TGCT cis rs6089584 0.854 rs6061985 chr20:60622362 T/C cg16423285 chr20:60520624 NA -0.6 -6.41 -0.5 2.76e-9 Body mass index; TGCT cis rs16867321 0.950 rs4667228 chr2:181498824 T/A cg23363182 chr2:181467187 NA -0.38 -5.55 -0.45 1.62e-7 Obesity; TGCT cis rs9660180 0.836 rs12038134 chr1:1703865 T/A cg17747265 chr1:1875780 NA -0.38 -7.18 -0.54 5.62e-11 Body mass index; TGCT cis rs2836950 0.565 rs2836942 chr21:40591381 A/G cg11644478 chr21:40555479 PSMG1 -0.52 -4.84 -0.4 3.83e-6 Menarche (age at onset); TGCT cis rs1797885 0.546 rs2454421 chr3:12601105 C/T cg05775895 chr3:12838266 CAND2 0.5 4.86 0.4 3.41e-6 Immature fraction of reticulocytes; TGCT cis rs6570726 0.935 rs430561 chr6:145813140 C/T cg23711669 chr6:146136114 FBXO30 0.73 6.89 0.53 2.55e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs13191362 0.935 rs116735807 chr6:163010615 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10206020 0.885 rs6720797 chr2:1574340 T/C cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs2455799 0.573 rs2470539 chr3:15717844 C/T cg16303742 chr3:15540471 COLQ -0.24 -4.81 -0.4 4.24e-6 Mean platelet volume; TGCT cis rs1865760 0.929 rs9467646 chr6:25957408 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.2 0.49 7.73e-9 Height; TGCT cis rs854765 0.583 rs950966 chr17:17783748 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.98 -0.58 8.43e-13 Total body bone mineral density; TGCT cis rs7312933 0.703 rs2406567 chr12:42551479 G/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 4.99 0.41 1.99e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7666738 0.830 rs4699601 chr4:99034429 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6570726 0.755 rs2092297 chr6:145893765 A/G cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs644799 0.965 rs549695 chr11:95617788 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.74 7.66 0.57 4.71e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11792861 0.816 rs7027263 chr9:111699569 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 5.0 0.41 1.88e-6 Menarche (age at onset); TGCT cis rs9527 0.545 rs7915816 chr10:104881750 A/G cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs858239 0.539 rs10280815 chr7:23188370 A/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs986417 0.748 rs10142927 chr14:61041956 A/G cg27398547 chr14:60952738 C14orf39 1.42 10.64 0.69 3.42e-19 Gut microbiota (bacterial taxa); TGCT cis rs7568458 0.709 rs11895401 chr2:85753847 C/T cg17127132 chr2:85788382 GGCX 0.51 4.73 0.39 5.89e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs8177253 1.000 rs8177272 chr3:133482870 C/T cg08048268 chr3:133502702 NA -0.66 -9.85 -0.66 2.89e-17 Iron status biomarkers; TGCT cis rs1878931 0.501 rs9635563 chr16:3416940 A/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.12 0.54 7.59e-11 Body mass index (adult); TGCT cis rs7552404 0.924 rs67757078 chr1:76169456 G/A cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9905704 0.647 rs9898048 chr17:57108543 C/T cg05425664 chr17:57184151 TRIM37 -0.68 -5.61 -0.45 1.25e-7 Testicular germ cell tumor; TGCT cis rs801193 1.000 rs1553609 chr7:66197139 T/C cg00343986 chr7:65444356 GUSB 0.23 5.14 0.42 1.06e-6 Aortic root size; TGCT cis rs6939532 0.522 rs9366652 chr6:26354219 C/G cg05738196 chr6:26577821 NA -0.52 -5.02 -0.41 1.73e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs832540 0.669 rs832538 chr5:56200016 C/T cg20203395 chr5:56204925 C5orf35 -0.55 -4.89 -0.4 3.03e-6 Coronary artery disease; TGCT cis rs7772486 0.754 rs1415747 chr6:146077249 A/G cg23711669 chr6:146136114 FBXO30 0.93 10.78 0.7 1.61e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs651907 0.557 rs11914318 chr3:101453858 C/T cg12386194 chr3:101231763 SENP7 0.48 4.63 0.38 9.23e-6 Colorectal cancer; TGCT cis rs9611565 0.512 rs2899347 chr22:42158204 T/C cg13695892 chr22:41940480 POLR3H 0.87 8.24 0.59 2.06e-13 Vitiligo; TGCT cis rs4776059 1.000 rs3751614 chr15:52901638 T/C cg25063058 chr15:52860530 ARPP19 0.52 4.73 0.39 6.01e-6 Schizophrenia; TGCT cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs13177918 0.559 rs12109637 chr5:149834718 G/T cg14059543 chr5:149831962 NA -0.62 -7.91 -0.58 1.19e-12 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs950880 0.560 rs6733174 chr2:102929012 T/C cg09003973 chr2:102972529 NA -0.53 -4.69 -0.39 7.02e-6 Serum protein levels (sST2); TGCT cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg06212747 chr3:49208901 KLHDC8B 0.6 5.44 0.44 2.75e-7 Parkinson's disease; TGCT cis rs7267979 0.966 rs2500433 chr20:25296335 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs11942114 chr4:99066261 C/G cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10791097 0.694 rs4456262 chr11:130755813 C/T cg12179176 chr11:130786555 SNX19 -0.84 -5.99 -0.47 2.07e-8 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4888262 0.545 rs7195499 chr16:74693973 C/G cg01733217 chr16:74700730 RFWD3 0.73 7.3 0.55 3.08e-11 Testicular germ cell tumor; TGCT trans rs1814175 0.817 rs28502006 chr11:50049930 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs7172809 0.573 rs17383078 chr15:77484746 C/T cg22256960 chr15:77711686 NA -0.49 -4.63 -0.38 9.01e-6 Glucose homeostasis traits; TGCT cis rs155076 1.000 rs567166 chr13:21837519 T/C cg11317459 chr13:21872234 NA -1.42 -12.02 -0.73 1.53e-22 White matter hyperintensity burden; TGCT cis rs7681440 0.904 rs2870029 chr4:90772057 G/T cg14346243 chr4:90757452 SNCA -0.57 -5.5 -0.44 2.04e-7 Dementia with Lewy bodies; TGCT cis rs2554380 0.943 rs11636516 chr15:84361773 A/T cg14598478 chr15:84363061 ADAMTSL3 -0.41 -4.46 -0.37 1.84e-5 Height; TGCT cis rs62229266 0.682 rs11700546 chr21:37371139 A/C cg08632701 chr21:37451849 NA -0.15 -4.6 -0.38 1.03e-5 Mitral valve prolapse; TGCT cis rs28386778 0.897 rs1062788 chr17:61896127 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs1256061 0.630 rs1256030 chr14:64747170 A/G cg21174375 chr14:64681225 SYNE2 0.21 4.5 0.37 1.55e-5 Hemoglobin concentration;Red blood cell count;Hematocrit; TGCT cis rs6598955 0.670 rs6598942 chr1:26531034 C/T cg01614726 chr1:26633154 UBXN11 0.48 4.52 0.38 1.44e-5 Obesity-related traits; TGCT cis rs986417 1.000 rs6573313 chr14:60961299 A/G cg27398547 chr14:60952738 C14orf39 1.49 10.81 0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs6570726 0.935 rs384806 chr6:145814889 C/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3091242 0.933 rs11802413 chr1:25760920 A/G cg10117171 chr1:25599238 RHD 0.32 5.27 0.43 5.82e-7 Erythrocyte sedimentation rate; TGCT cis rs1218582 0.772 rs6683557 chr1:154852307 C/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.35 -0.55 2.36e-11 Prostate cancer; TGCT cis rs7618915 0.547 rs11130323 chr3:52770277 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs3770081 1.000 rs1036554 chr2:86236099 G/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.1 -4.5 -0.37 1.52e-5 Facial emotion recognition (sad faces); TGCT cis rs7248779 0.512 rs3848635 chr19:2410332 T/C cg22729335 chr19:2427816 TIMM13 1.13 13.34 0.77 9.83e-26 Cortisol levels (saliva); TGCT cis rs796364 0.760 rs56285751 chr2:200919836 C/T cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs12902680 0.739 rs1402118 chr15:46392288 T/C cg13605988 chr15:45421612 DUOX1;DUOXA1 0.32 4.45 0.37 1.87e-5 Neuroticism; TGCT cis rs4076764 0.957 rs4443867 chr1:163434917 T/C cg24596788 chr1:163392923 NA -0.17 -4.75 -0.39 5.46e-6 Motion sickness; TGCT cis rs4077468 1.000 rs4077469 chr1:205914885 C/T cg24503407 chr1:205819492 PM20D1 -0.39 -4.59 -0.38 1.07e-5 Cystic fibrosis-related diabetes; TGCT cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg18735214 chr6:43276756 CRIP3 -0.55 -4.83 -0.4 3.94e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9733 0.596 rs17606613 chr1:150683015 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs7584330 0.737 rs12469894 chr2:238365528 T/C cg14458575 chr2:238380390 NA 0.51 8.14 0.59 3.53e-13 Prostate cancer; TGCT cis rs151997 1.000 rs152854 chr5:50223206 G/A cg06027927 chr5:50259733 NA -0.48 -4.84 -0.4 3.72e-6 Callous-unemotional behaviour; TGCT cis rs17401966 0.838 rs12132134 chr1:10378428 A/G cg19773385 chr1:10388646 KIF1B -0.24 -5.38 -0.44 3.56e-7 Hepatocellular carcinoma; TGCT cis rs8054556 0.740 rs3924855 chr16:29954955 A/G cg26859862 chr16:30389551 SEPT1 -0.56 -4.9 -0.4 2.91e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2230307 0.536 rs834164 chr1:100603948 A/C cg24955406 chr1:100503596 HIAT1 -0.71 -4.75 -0.39 5.44e-6 Carotid intima media thickness; TGCT cis rs931608 0.640 rs2082478 chr19:22539848 G/A cg15554505 chr19:22123728 NA -0.63 -4.57 -0.38 1.18e-5 Dental caries;Response to statins (LDL cholesterol change); TGCT trans rs916888 0.610 rs199442 chr17:44820122 G/A cg22968622 chr17:43663579 NA 1.05 10.05 0.67 9.4e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6964587 0.773 rs10488514 chr7:91951842 C/A cg17063962 chr7:91808500 NA 0.84 8.33 0.6 1.29e-13 Breast cancer; TGCT cis rs131777 0.547 rs131753 chr22:51022862 A/G cg25309564 chr22:51001381 C22orf41 0.55 5.22 0.42 7.17e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6693567 0.565 rs696617 chr1:150376311 G/T cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs7246657 0.941 rs67293224 chr19:37803248 C/T cg18154014 chr19:37997991 ZNF793 0.91 6.29 0.49 5.01e-9 Coronary artery calcification; TGCT cis rs1857353 1.000 rs1858631 chr1:75886523 G/C cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs7772486 0.654 rs6928007 chr6:146074941 G/A cg23711669 chr6:146136114 FBXO30 -0.88 -9.63 -0.65 1.01e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs12510870 0.599 rs1590116 chr4:74389830 A/C cg05868023 chr4:75230803 EREG 0.56 5.07 0.41 1.42e-6 Iris color (b* coordinate); TGCT cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg20607798 chr8:58055168 NA 0.45 4.66 0.39 7.88e-6 Developmental language disorder (linguistic errors); TGCT cis rs1847202 0.859 rs13079651 chr3:72922181 C/T cg25664220 chr3:72788482 NA -0.37 -4.79 -0.4 4.63e-6 Motion sickness; TGCT cis rs8177253 0.829 rs9813689 chr3:133514822 C/T cg01448562 chr3:133502909 NA -0.34 -6.9 -0.53 2.37e-10 Iron status biomarkers; TGCT cis rs9372498 0.536 rs62424175 chr6:118797381 T/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.76 -0.39 5.36e-6 Diastolic blood pressure; TGCT cis rs74544699 0.609 rs72855280 chr4:74835131 C/A cg16072462 chr4:74847758 PF4 0.71 4.82 0.4 4.05e-6 Growth-regulated protein alpha levels; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.08 15.31 0.81 2.29e-30 Prudent dietary pattern; TGCT cis rs1008375 1.000 rs10939738 chr4:17604295 G/C cg16339924 chr4:17578868 LAP3 0.64 5.22 0.42 7.4e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs981844 0.696 rs17030349 chr4:154636039 C/T cg14289246 chr4:154710475 SFRP2 0.94 7.38 0.55 1.99e-11 Response to statins (LDL cholesterol change); TGCT cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.46 4.58 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs2070488 0.695 rs6599201 chr3:38476614 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.8 7.96 0.58 9.4e-13 Electrocardiographic conduction measures; TGCT cis rs9379774 0.623 rs1876373 chr6:25442684 G/C cg13320114 chr6:26216906 HIST1H2AE;HIST1H2BG 0.75 4.72 0.39 6.15e-6 Coronary artery disease; TGCT cis rs7267979 0.738 rs2892409 chr20:25638138 C/T cg21995068 chr20:25989032 LOC100134868 -0.44 -5.42 -0.44 2.94e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs644799 0.625 rs1255177 chr11:95471495 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.5 4.8 0.4 4.53e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1008375 1.000 rs10939744 chr4:17664473 G/T cg16339924 chr4:17578868 LAP3 0.55 4.73 0.39 5.96e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs838147 0.537 rs603985 chr19:49207257 T/C cg04599840 chr19:48886497 KDELR1 0.22 4.58 0.38 1.14e-5 Dietary macronutrient intake; TGCT cis rs4727027 0.754 rs917124 chr7:148851213 C/T cg15662616 chr7:148823355 ZNF425;ZNF398 0.55 4.52 0.38 1.42e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7959452 0.530 rs12811632 chr12:69755003 G/A cg14784868 chr12:69753453 YEATS4 0.83 8.84 0.62 7.84e-15 Blood protein levels; TGCT cis rs533581 0.873 rs555191 chr16:88978850 C/T cg16701003 chr16:89028210 CBFA2T3 0.36 4.86 0.4 3.53e-6 Social autistic-like traits; TGCT trans rs2727020 0.595 rs10769583 chr11:49483193 G/A cg11707556 chr5:10655725 ANKRD33B -0.36 -6.9 -0.53 2.36e-10 Coronary artery disease; TGCT cis rs11874712 0.527 rs4257298 chr18:43689353 C/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.49 4.86 0.4 3.47e-6 Migraine - clinic-based; TGCT cis rs916888 0.773 rs199439 chr17:44793503 A/G cg15921436 chr17:44337874 NA 0.59 8.18 0.59 2.85e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2249625 0.526 rs17781511 chr6:72845455 C/T cg24401219 chr6:72892597 RIMS1 0.57 4.46 0.37 1.84e-5 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs74233809 0.710 rs4147157 chr10:104536360 G/A cg05855489 chr10:104503620 C10orf26 0.81 4.57 0.38 1.15e-5 Birth weight; TGCT cis rs250677 0.958 rs36078 chr5:148430567 G/A cg18129178 chr5:148520854 ABLIM3 -0.42 -5.79 -0.46 5.4e-8 Breast cancer; TGCT cis rs2749592 0.513 rs9417249 chr10:37837155 C/T cg25427524 chr10:38739819 LOC399744 0.3 5.16 0.42 9.41e-7 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9929218 0.551 rs2296405 chr16:68721470 C/T cg01251360 chr16:68772225 CDH1 0.25 4.63 0.38 8.9e-6 Colorectal cancer; TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg16325326 chr1:53192061 ZYG11B 0.59 7.1 0.54 8.48e-11 Monocyte count; TGCT cis rs763014 0.932 rs2384972 chr16:674424 G/A cg00908189 chr16:619842 PIGQ 0.87 10.65 0.69 3.27e-19 Height; TGCT cis rs79349575 0.783 rs4793992 chr17:47008207 A/G cg26022315 chr17:47021804 SNF8 0.47 4.61 0.38 9.8200000000000008e-06 Type 2 diabetes; TGCT cis rs4595586 0.545 rs3858554 chr12:39381460 C/T cg26963002 chr12:38532352 NA 0.54 4.48 0.37 1.66e-5 Morning vs. evening chronotype; TGCT cis rs7523050 0.643 rs17563938 chr1:109401654 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs6429082 0.755 rs291367 chr1:235690800 G/A cg26050004 chr1:235667680 B3GALNT2 0.65 6.07 0.48 1.44e-8 Adiposity; TGCT cis rs1862618 0.671 rs2591964 chr5:56236900 T/G cg12311346 chr5:56204834 C5orf35 0.57 6.13 0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs2945232 1 rs2945232 chr8:8098038 T/C cg06636001 chr8:8085503 FLJ10661 0.9 9.11 0.63 1.82e-15 Schizophrenia; TGCT cis rs7954584 0.504 rs10840633 chr12:122377511 A/T cg13699009 chr12:122356056 WDR66 0.28 5.45 0.44 2.55e-7 Mean corpuscular volume; TGCT cis rs514406 0.861 rs4926932 chr1:53247495 C/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs17221829 0.764 rs7931085 chr11:89386197 C/T cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs61990749 0.597 rs4903643 chr14:78254791 C/T cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs7914558 0.966 rs10786727 chr10:104698523 G/A cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4919694 0.572 rs72846714 chr10:104878454 G/A cg04362960 chr10:104952993 NT5C2 0.99 7.01 0.53 1.36e-10 Arsenic metabolism; TGCT cis rs6840360 0.593 rs2175409 chr4:152701656 A/G cg22705602 chr4:152727874 NA -0.35 -6.01 -0.47 1.95e-8 Intelligence (multi-trait analysis); TGCT cis rs9549367 0.713 rs2146750 chr13:113822530 A/G cg18105134 chr13:113819100 PROZ 0.38 5.91 0.47 3.05e-8 Platelet distribution width; TGCT cis rs644799 0.710 rs666398 chr11:95551136 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.64 0.61 2.36e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs13256369 0.755 rs12680167 chr8:8562467 A/G cg17143192 chr8:8559678 CLDN23 0.56 5.23 0.43 7.03e-7 Obesity-related traits; TGCT cis rs6815814 0.950 rs11722813 chr4:38810769 C/T cg02016764 chr4:38805732 TLR1 -0.39 -6.05 -0.48 1.61e-8 Breast cancer; TGCT cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg11890956 chr21:40555474 PSMG1 1.1 12.36 0.74 2.27e-23 Cognitive function; TGCT cis rs4930561 0.714 rs7126326 chr11:67947275 T/G cg04465784 chr11:67976953 SUV420H1 -0.38 -5.47 -0.44 2.37e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs7666738 0.830 rs1365458 chr4:98950961 C/T cg18180107 chr4:99064573 C4orf37 0.59 5.29 0.43 5.35e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7246657 0.943 rs8111782 chr19:37867904 A/G cg18154014 chr19:37997991 ZNF793 1.0 6.69 0.52 6.81e-10 Coronary artery calcification; TGCT cis rs2180341 0.960 rs3756996 chr6:127664258 G/C cg27446573 chr6:127587934 RNF146 1.19 10.56 0.69 5.48e-19 Breast cancer; TGCT cis rs1008375 0.932 rs13134570 chr4:17692863 C/T cg18681998 chr4:17616180 MED28 -0.83 -7.8 -0.57 2.22e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.48 -4.44 -0.37 1.93e-5 Prudent dietary pattern; TGCT cis rs7587476 0.601 rs17489363 chr2:215674341 A/G cg04004882 chr2:215674386 BARD1 -0.65 -5.13 -0.42 1.09e-6 Neuroblastoma; TGCT cis rs7681440 0.904 rs28403500 chr4:90769729 T/G cg01966878 chr4:90757139 SNCA -0.25 -4.53 -0.38 1.39e-5 Dementia with Lewy bodies; TGCT cis rs3845702 1.000 rs3768837 chr2:180835792 T/A cg01881094 chr2:180872142 CWC22 -0.68 -6.06 -0.48 1.51e-8 Schizophrenia; TGCT cis rs617219 0.726 rs7717669 chr5:78452983 A/C cg09550809 chr5:78407562 BHMT 0.39 5.46 0.44 2.54e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs80282103 0.618 rs11250264 chr10:1151723 A/C cg18964960 chr10:1102726 WDR37 0.98 4.57 0.38 1.15e-5 Glomerular filtration rate (creatinine); TGCT cis rs1395 1.000 rs4665958 chr2:27443196 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.73 0.52 5.6e-10 Blood metabolite levels; TGCT cis rs73001065 0.636 rs10415849 chr19:19505087 C/T cg03709012 chr19:19516395 GATAD2A 0.86 4.58 0.38 1.12e-5 LDL cholesterol; TGCT cis rs9653442 0.675 rs1115910 chr2:100647872 A/G cg07810366 chr2:100720526 AFF3 -0.4 -6.54 -0.51 1.43e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2115630 0.818 rs7176522 chr15:85215383 C/G cg12863693 chr15:85201151 NMB -0.33 -4.45 -0.37 1.88e-5 P wave terminal force; TGCT cis rs6964587 0.967 rs2188153 chr7:91595117 G/T cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs10510102 0.872 rs7907815 chr10:123725466 G/T cg23691251 chr10:123688108 ATE1 -0.59 -4.64 -0.38 8.68e-6 Breast cancer; TGCT trans rs1973993 0.967 rs6679458 chr1:96946253 G/T cg10631902 chr5:14652156 NA 0.29 6.73 0.52 5.57e-10 Weight; TGCT cis rs9733 0.519 rs10788792 chr1:150638572 T/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs7547997 0.685 rs11264965 chr1:158352400 T/G cg03528325 chr1:158223921 CD1A 0.33 4.56 0.38 1.22e-5 QRS duration; TGCT cis rs28595532 0.920 rs114213539 chr4:119758794 G/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs1448094 0.534 rs11613070 chr12:86167544 T/A cg02569458 chr12:86230093 RASSF9 0.38 4.49 0.37 1.61e-5 Major depressive disorder; TGCT cis rs9972944 0.756 rs6504352 chr17:63765287 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.31 -0.43 4.9e-7 Total body bone mineral density; TGCT trans rs459571 0.959 rs465535 chr9:136910905 C/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.75 -8.02 -0.58 6.93e-13 Platelet distribution width; TGCT cis rs67478160 0.643 rs8004408 chr14:104203938 G/A cg26031613 chr14:104095156 KLC1 -0.63 -6.36 -0.5 3.45e-9 Schizophrenia; TGCT cis rs66573146 1.000 rs6812771 chr4:6964048 G/A cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs9926296 0.605 rs3743859 chr16:89846050 A/G cg03388025 chr16:89894329 SPIRE2 -0.53 -9.4 -0.65 3.5e-16 Vitiligo; TGCT cis rs478304 0.654 rs6591185 chr11:65455742 A/G cg17480646 chr11:65405466 SIPA1 -0.61 -8.27 -0.6 1.79e-13 Acne (severe); TGCT cis rs860295 0.500 rs12032631 chr1:155995080 G/A cg05700447 chr1:155978627 NA -0.19 -4.66 -0.39 8.09e-6 Body mass index; TGCT cis rs2832191 0.671 rs2409332 chr21:30512779 G/A cg24692254 chr21:30365293 RNF160 -0.61 -5.41 -0.44 3.08e-7 Dental caries; TGCT cis rs9399135 0.967 rs13199205 chr6:135286505 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.75 0.39 5.48e-6 Red blood cell count; TGCT cis rs875971 0.964 rs9691480 chr7:65944306 A/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs5769765 0.865 rs9616369 chr22:50304591 A/C cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.61 0.45 1.24e-7 Schizophrenia; TGCT cis rs7246657 0.722 rs10403173 chr19:38078680 G/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs3820068 0.655 rs72645823 chr1:15887442 C/T cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs4665809 1.000 rs7599132 chr2:26279810 A/T cg25036284 chr2:26402008 FAM59B 0.53 4.71 0.39 6.48e-6 Gut microbiome composition (summer); TGCT cis rs2535633 0.631 rs11915851 chr3:53096047 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.92 -0.4 2.73e-6 Body mass index; TGCT cis rs6714710 0.603 rs34503448 chr2:98587288 A/G cg26665480 chr2:98280029 ACTR1B 0.66 6.26 0.49 5.84e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs1799949 1.000 rs3092988 chr17:41201702 C/T cg23758822 chr17:41437982 NA 0.76 7.12 0.54 7.84e-11 Menopause (age at onset); TGCT cis rs6933660 0.760 rs1825368 chr6:151775259 C/A cg14262678 chr6:151773367 RMND1;C6orf211 0.55 5.21 0.42 7.61e-7 Menarche (age at onset); TGCT cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs523522 0.962 rs3213565 chr12:120992401 C/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs28595532 0.920 rs114653217 chr4:119769216 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs4242434 0.892 rs4872527 chr8:22496048 G/A cg03733263 chr8:22462867 KIAA1967 1.16 17.73 0.85 8.57e-36 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2236918 0.687 rs851778 chr1:242037110 A/G cg04158730 chr1:242011433 EXO1 0.56 5.16 0.42 9.57e-7 Menopause (age at onset); TGCT cis rs2075371 1.000 rs1862050 chr7:133980999 T/C cg11752832 chr7:134001865 SLC35B4 0.7 6.53 0.51 1.51e-9 Mean platelet volume; TGCT cis rs1801251 1.000 rs283468 chr2:233658309 C/T cg25237894 chr2:233734115 C2orf82 0.27 4.68 0.39 7.35e-6 Coronary artery disease; TGCT cis rs7666738 0.830 rs6532720 chr4:99043781 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs208520 0.690 rs4618506 chr6:66756889 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.76 -0.69 1.76e-19 Exhaled nitric oxide output; TGCT cis rs7772486 0.764 rs9399569 chr6:146242942 C/T cg23711669 chr6:146136114 FBXO30 -0.85 -9.7 -0.66 6.73e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs6987853 0.830 rs4737048 chr8:42359035 G/T cg20539142 chr8:42623718 CHRNA6 0.19 4.52 0.38 1.44e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs1862618 0.802 rs832547 chr5:56183941 C/G cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs28374715 0.617 rs16971735 chr15:41563970 C/G cg18705301 chr15:41695430 NDUFAF1 -0.63 -8.21 -0.59 2.43e-13 Ulcerative colitis; TGCT cis rs17711722 0.523 rs365896 chr7:65510697 A/G cg00343986 chr7:65444356 GUSB -0.21 -5.32 -0.43 4.59e-7 Calcium levels; TGCT cis rs2439831 0.850 rs28595038 chr15:44044859 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs7635838 0.654 rs346086 chr3:11272932 G/T cg00170343 chr3:11313890 ATG7 0.66 6.18 0.49 8.61e-9 HDL cholesterol; TGCT cis rs10479542 1.000 rs10479542 chr5:178981241 T/A cg19723775 chr5:179050963 HNRNPH1 0.53 5.29 0.43 5.31e-7 Lung cancer; TGCT cis rs873946 0.517 rs7071784 chr10:134559980 T/C cg27286337 chr10:134555280 INPP5A 0.41 5.11 0.42 1.2e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4378999 0.660 rs7433217 chr3:50987194 G/A ch.3.1075622R chr3:50010873 RBM6 -0.36 -4.56 -0.38 1.23e-5 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); TGCT cis rs473651 0.935 rs1103770 chr2:239339281 G/C cg18131467 chr2:239335373 ASB1 0.95 9.87 0.66 2.62e-17 Multiple system atrophy; TGCT cis rs9467773 0.550 rs9379874 chr6:26440429 A/T cg05738196 chr6:26577821 NA -0.52 -5.49 -0.44 2.18e-7 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.614 rs3748930 chr2:101010082 G/C cg14675211 chr2:100938903 LONRF2 0.5 4.82 0.4 4.16e-6 Intelligence (multi-trait analysis); TGCT cis rs6121246 0.909 rs6060821 chr20:30294034 C/T cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs4862750 0.872 rs4862748 chr4:187877388 C/T cg03452623 chr4:187889614 NA 0.41 5.8 0.46 5.14e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs3796352 0.571 rs11713926 chr3:53155072 C/T cg15956490 chr3:53032818 SFMBT1 0.53 6.22 0.49 6.87e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs832540 1.000 rs252913 chr5:56195846 C/T cg12311346 chr5:56204834 C5orf35 0.46 4.85 0.4 3.66e-6 Coronary artery disease; TGCT cis rs9372253 1.000 rs7740028 chr6:110719180 A/G cg00083206 chr6:110721305 DDO -0.44 -6.67 -0.51 7.55e-10 Platelet distribution width; TGCT cis rs10504229 0.724 rs58715581 chr8:58134568 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs10492972 0.523 rs12746471 chr1:10475011 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.8 -0.4 4.49e-6 Multiple sclerosis; TGCT cis rs7666738 0.830 rs10470893 chr4:99038756 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.834 rs1563107 chr2:99701276 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.64 5.49 0.44 2.18e-7 Chronic sinus infection; TGCT cis rs4699052 1.000 rs7661702 chr4:104140129 C/G cg16532752 chr4:104119610 CENPE -0.58 -5.59 -0.45 1.4e-7 Testicular germ cell tumor; TGCT cis rs2299587 0.554 rs3913558 chr8:17747909 T/G cg01800426 chr8:17659068 MTUS1 -0.58 -5.12 -0.42 1.16e-6 Economic and political preferences; TGCT cis rs28595532 0.920 rs116366070 chr4:119764180 A/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT trans rs877282 0.838 rs11253373 chr10:774857 A/G cg22713356 chr15:30763199 NA 1.12 9.83 0.66 3.23e-17 Uric acid levels; TGCT cis rs11718455 0.920 rs34909426 chr3:44000472 G/A cg08738300 chr3:44038990 NA 0.83 6.19 0.49 8.13e-9 Coronary artery disease; TGCT cis rs5769707 0.874 rs9616714 chr22:50050859 G/A cg10356904 chr22:49881777 NA -0.23 -4.66 -0.39 7.88e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs10276381 0.786 rs10272155 chr7:28246989 A/G cg23620719 chr7:28220237 JAZF1 0.93 5.69 0.46 8.65e-8 Crohn's disease; TGCT cis rs727563 0.636 rs2413653 chr22:42106996 T/C cg17554472 chr22:41940697 POLR3H 0.47 5.04 0.41 1.63e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10504229 1.000 rs66840104 chr8:58190001 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2271316 0.587 rs11078659 chr17:6903944 G/A cg05215272 chr17:6899095 ALOX12 0.45 5.38 0.44 3.57e-7 Blood metabolite levels; TGCT cis rs1799949 1.000 rs1799966 chr17:41223094 T/C cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 2.93e-27 Menopause (age at onset); TGCT cis rs9326248 1.000 rs585849 chr11:117069061 A/G cg16524733 chr11:117070046 TAGLN 0.33 4.73 0.39 5.9e-6 Blood protein levels; TGCT cis rs9486719 1.000 rs11752584 chr6:96884952 C/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs9303401 0.921 rs34102441 chr17:56877414 A/G cg12560992 chr17:57184187 TRIM37 0.54 5.61 0.45 1.26e-7 Cognitive test performance; TGCT cis rs4563143 0.502 rs73029061 chr19:29283980 T/A cg04546413 chr19:29218101 NA 0.86 7.0 0.53 1.45e-10 Methadone dose in opioid dependence; TGCT cis rs2243480 0.803 rs35268390 chr7:65416536 C/G cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs9549367 0.673 rs575453 chr13:113837871 C/A cg18105134 chr13:113819100 PROZ 0.46 8.58 0.61 3.25e-14 Platelet distribution width; TGCT cis rs6964587 1.000 rs11982047 chr7:91705274 G/A cg22709100 chr7:91322751 NA 0.27 4.46 0.37 1.84e-5 Breast cancer; TGCT cis rs10504229 0.815 rs72650879 chr8:58164648 A/G cg24829409 chr8:58192753 C8orf71 -0.57 -4.72 -0.39 6.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg18735214 chr6:43276756 CRIP3 -0.56 -4.89 -0.4 3.05e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4665630 0.522 rs2551351 chr2:23914065 C/T cg08063864 chr2:24346004 PFN4;LOC375190 -1.22 -5.82 -0.46 4.81e-8 Hypertension; TGCT cis rs2657888 1.000 rs7309685 chr12:56935413 A/G cg23932658 chr12:57637574 STAC3 -0.52 -4.83 -0.4 3.91e-6 Adiponectin levels; TGCT cis rs7539409 0.833 rs2057083 chr1:84269942 T/G cg10977910 chr1:84465055 TTLL7 0.91 5.13 0.42 1.08e-6 Alzheimer's disease; TGCT cis rs8051431 0.876 rs4788591 chr16:72020323 A/G cg06353428 chr16:71660113 MARVELD3 0.56 4.47 0.37 1.73e-5 LDL cholesterol levels; TGCT cis rs4819052 1.000 rs13047688 chr21:46669290 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.8 6.14 0.48 1.02e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs1814175 0.616 rs4881723 chr11:49788566 G/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.32 -0.71 7.95e-21 Height; TGCT trans rs1814175 0.817 rs7927373 chr11:49957640 A/C cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs1862618 0.713 rs832549 chr5:56183542 C/T cg12311346 chr5:56204834 C5orf35 -0.67 -6.77 -0.52 4.59e-10 Initial pursuit acceleration; TGCT cis rs751728 1.000 rs6920075 chr6:33731797 C/T cg13859433 chr6:33739653 LEMD2 -0.39 -7.42 -0.55 1.65e-11 Crohn's disease; TGCT cis rs1552244 0.882 rs66559400 chr3:10012551 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs73198271 0.920 rs11783112 chr8:8606193 C/T ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.73 -0.39 5.95e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs17384381 0.953 rs12717763 chr1:85808164 A/T cg16011679 chr1:85725395 C1orf52 0.81 6.36 0.5 3.47e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs1008375 0.931 rs10008337 chr4:17593849 G/C cg18681998 chr4:17616180 MED28 1.0 10.01 0.67 1.2e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6882076 1.000 rs7724832 chr5:156381370 C/T cg12943317 chr5:156479607 HAVCR1 -0.32 -5.6 -0.45 1.33e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs2153535 0.601 rs2015281 chr6:8539673 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs6570726 0.620 rs12201226 chr6:145913419 A/T cg05347473 chr6:146136440 FBXO30 0.62 5.7 0.46 8.22e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.966 rs2145126 chr20:25263648 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3820068 0.581 rs6669417 chr1:15922371 G/T cg05660106 chr1:15850417 CASP9 0.79 8.54 0.61 4.01e-14 Systolic blood pressure; TGCT cis rs60871478 1.000 rs9195 chr7:825786 C/T cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.48 -4.75 -0.39 5.5e-6 Cerebrospinal P-tau181p levels; TGCT cis rs7618915 0.501 rs13085775 chr3:52678370 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs9457247 0.967 rs2769355 chr6:167380493 G/A cg25258033 chr6:167368657 RNASET2 -0.18 -4.49 -0.37 1.63e-5 Crohn's disease; TGCT cis rs9549367 0.789 rs7338235 chr13:113888687 T/C cg00898013 chr13:113819073 PROZ -0.38 -4.66 -0.39 8.1e-6 Platelet distribution width; TGCT cis rs7647973 0.560 rs77473999 chr3:49777660 T/C cg03060546 chr3:49711283 APEH -0.61 -5.14 -0.42 1.03e-6 Menarche (age at onset); TGCT cis rs9611565 0.559 rs5758412 chr22:42080803 T/A cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Vitiligo; TGCT cis rs2070488 0.965 rs1984312 chr3:38538466 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.88 -9.19 -0.64 1.13e-15 Electrocardiographic conduction measures; TGCT cis rs6088580 0.634 rs4911418 chr20:32994257 G/A cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.44 0.56 1.45e-11 Platelet count; TGCT cis rs6088580 0.634 rs6059878 chr20:33087166 A/T cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs2013441 1.000 rs9325894 chr17:20197101 T/C cg18979559 chr17:20280153 CCDC144C -0.49 -5.04 -0.41 1.59e-6 Obesity-related traits; TGCT cis rs11053548 0.602 rs11053554 chr12:10175667 G/A cg24820250 chr12:10084936 CLEC2A 0.25 4.51 0.38 1.49e-5 Systolic blood pressure in sickle cell anemia; TGCT cis rs59104589 0.959 rs60624480 chr2:242297118 G/A cg21155796 chr2:242212141 HDLBP 0.55 4.75 0.39 5.56e-6 Fibrinogen levels; TGCT cis rs6835098 0.962 rs4377567 chr4:174083590 C/G cg08422745 chr4:174089978 GALNT7 0.91 10.78 0.7 1.59e-19 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs1799949 0.965 rs33961729 chr17:41287924 C/A cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.93 0.4 2.63e-6 Menopause (age at onset); TGCT cis rs66573146 1.000 rs28729690 chr4:6962061 C/T cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs62064224 0.905 rs9891969 chr17:30627085 C/T cg18200150 chr17:30822561 MYO1D 0.45 5.83 0.46 4.57e-8 Schizophrenia; TGCT cis rs801193 0.569 rs2707847 chr7:66202871 C/G cg11764359 chr7:65958608 NA 0.54 4.79 0.4 4.68e-6 Aortic root size; TGCT cis rs2688608 0.592 rs7909544 chr10:75484004 G/C cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs9291683 0.551 rs62295971 chr4:9978142 G/A cg11266682 chr4:10021025 SLC2A9 0.62 8.63 0.61 2.51e-14 Bone mineral density; TGCT cis rs6582630 0.638 rs1829584 chr12:38526299 G/T cg26384229 chr12:38710491 ALG10B -0.55 -4.89 -0.4 3.05e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs11534004 0.515 rs12533776 chr7:113689001 T/C cg21852992 chr7:112726869 GPR85 -0.35 -5.05 -0.41 1.53e-6 Schizophrenia; TGCT cis rs2730260 0.537 rs73169238 chr7:158883818 G/A cg09066883 chr7:157932951 PTPRN2 0.42 4.66 0.39 8.09e-6 Myopia (pathological); TGCT cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs7147624 1.000 rs4902408 chr14:66111901 A/T cg03016385 chr14:66212404 NA -0.48 -7.04 -0.53 1.17e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs8062405 0.824 rs4788085 chr16:28535003 A/G cg09754948 chr16:28834200 ATXN2L 0.63 5.01 0.41 1.79e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT trans rs208520 0.526 rs7771233 chr6:66819784 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -12.42 -0.74 1.68e-23 Exhaled nitric oxide output; TGCT cis rs6951245 0.872 rs113119264 chr7:1080564 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11252926 0.528 rs11252090 chr10:436547 C/T cg20256804 chr10:444983 DIP2C 0.21 4.66 0.39 8e-6 Psychosis in Alzheimer's disease; TGCT cis rs11252926 0.550 rs10904148 chr10:454551 G/T cg20256804 chr10:444983 DIP2C -0.22 -4.73 -0.39 6.02e-6 Psychosis in Alzheimer's disease; TGCT cis rs62402013 1 rs62402013 chr6:26915000 A/G cg26531700 chr6:26746687 NA 0.69 6.41 0.5 2.71e-9 Schizophrenia; TGCT cis rs7267979 1.000 rs2500418 chr20:25382268 C/T cg16686733 chr20:25566563 NINL -0.59 -6.05 -0.48 1.57e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg13397359 chr6:42928475 GNMT 0.67 5.92 0.47 2.89e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4986172 0.539 rs3744760 chr17:43195981 C/T cg10701640 chr17:43249399 NA -0.39 -4.84 -0.4 3.84e-6 Height; TGCT cis rs688020 1.000 rs688020 chr7:4228553 C/T cg23797551 chr7:4243526 SDK1 -0.24 -4.45 -0.37 1.89e-5 Liver fibrosis in pediatric non-alcoholic fatty acid liver disease; TGCT cis rs7769051 0.711 rs9493435 chr6:133088205 A/G cg22852734 chr6:133119734 C6orf192 1.14 6.78 0.52 4.32e-10 Type 2 diabetes nephropathy; TGCT cis rs7666738 0.830 rs4699580 chr4:98930673 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs8016982 0.963 rs7149672 chr14:81657336 A/G cg01989461 chr14:81687754 GTF2A1 0.56 4.52 0.38 1.45e-5 Schizophrenia; TGCT cis rs12477438 0.748 rs7558239 chr2:99640581 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs9926296 0.572 rs8046872 chr16:89841552 T/C cg08627397 chr16:89984028 MC1R -0.29 -4.57 -0.38 1.15e-5 Vitiligo; TGCT cis rs804280 0.565 rs2645453 chr8:11622001 G/A cg26752888 chr8:11627280 NEIL2 -0.52 -4.76 -0.39 5.29e-6 Myopia (pathological); TGCT cis rs11779988 0.545 rs397096 chr8:17798848 C/G cg01800426 chr8:17659068 MTUS1 0.61 5.04 0.41 1.57e-6 Breast cancer; TGCT cis rs2486288 0.656 rs12440356 chr15:45567529 T/C cg26924012 chr15:45694286 SPATA5L1 0.82 8.09 0.59 4.62e-13 Glomerular filtration rate; TGCT cis rs7681440 0.869 rs894280 chr4:90760883 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.62 -0.45 1.19e-7 Dementia with Lewy bodies; TGCT cis rs17376456 0.569 rs10476520 chr5:93058290 A/C cg21475434 chr5:93447410 FAM172A 0.6 4.9 0.4 2.92e-6 Diabetic retinopathy; TGCT cis rs6545883 0.965 rs2305155 chr2:61729258 A/G cg15711740 chr2:61764176 XPO1 -0.51 -4.6 -0.38 1.03e-5 Tuberculosis; TGCT cis rs77972916 0.505 rs6727824 chr2:43528377 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -5.68 -0.45 9.24e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs6558530 0.692 rs10105317 chr8:1701432 G/A cg09410841 chr8:1729607 CLN8 0.72 6.49 0.5 1.87e-9 Systolic blood pressure; TGCT cis rs478304 0.718 rs61744384 chr11:65387378 T/A cg27068330 chr11:65405492 SIPA1 -0.87 -8.89 -0.62 5.88e-15 Acne (severe); TGCT cis rs7909074 0.651 rs10900127 chr10:45390103 C/A cg05187965 chr10:45406764 TMEM72 -0.24 -4.78 -0.39 4.97e-6 Mean corpuscular volume; TGCT cis rs7659604 0.521 rs13130789 chr4:122690166 G/A cg19748678 chr4:122722346 EXOSC9 -0.56 -5.56 -0.45 1.61e-7 Type 2 diabetes; TGCT cis rs4366490 0.848 rs1939757 chr11:62903823 T/A cg21002970 chr11:62369079 MTA2 0.87 4.67 0.39 7.78e-6 Conotruncal heart defects; TGCT cis rs617219 0.698 rs72764988 chr5:78533584 G/C cg23514016 chr5:78407564 BHMT 0.34 5.09 0.42 1.29e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6912958 0.874 rs9294381 chr6:88152681 A/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.6 -5.84 -0.46 4.27e-8 Monocyte percentage of white cells; TGCT cis rs12220238 0.908 rs11000893 chr10:75905996 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs4973397 0.810 rs12993290 chr2:232279687 G/A cg09339159 chr2:232260559 B3GNT7 0.57 4.79 0.4 4.69e-6 Anti-saccade response; TGCT cis rs2456568 0.900 rs1518571 chr11:93667420 C/A cg17595323 chr11:93583763 C11orf90 -0.46 -5.86 -0.47 3.87e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4788570 0.566 rs72795867 chr16:71484465 A/G cg06353428 chr16:71660113 MARVELD3 -1.33 -7.9 -0.58 1.28e-12 Intelligence (multi-trait analysis); TGCT cis rs2594989 0.943 rs2606737 chr3:11398654 A/G cg00170343 chr3:11313890 ATG7 0.66 5.08 0.42 1.34e-6 Circulating chemerin levels; TGCT cis rs6901250 0.569 rs686708 chr6:117091683 A/G cg12892004 chr6:117198278 RFX6 0.37 4.77 0.39 5.09e-6 C-reactive protein levels; TGCT cis rs6540559 0.605 rs3753518 chr1:209977964 G/C cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs9581857 0.685 rs9319367 chr13:28042197 T/C cg22138327 chr13:27999177 GTF3A 0.72 4.62 0.38 9.33e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT trans rs11722228 0.522 rs62286604 chr4:10131161 A/G cg26043149 chr18:55253948 FECH 1.24 13.96 0.78 3.39e-27 Gout;Urate levels;Serum uric acid levels; TGCT cis rs12478296 0.685 rs35577962 chr2:242993575 A/G cg06360820 chr2:242988706 NA -0.61 -4.68 -0.39 7.26e-6 Obesity-related traits; TGCT trans rs941408 1.000 rs1736181 chr19:2797703 C/T cg22153745 chr1:153894579 GATAD2B -0.65 -7.1 -0.54 8.37e-11 Total cholesterol levels; TGCT cis rs2980439 0.557 rs2976876 chr8:8318850 T/C cg15556689 chr8:8085844 FLJ10661 0.7 6.4 0.5 2.85e-9 Neuroticism; TGCT cis rs7772486 0.623 rs9485021 chr6:146068797 A/G cg05347473 chr6:146136440 FBXO30 -0.49 -4.52 -0.38 1.42e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1371867 0.875 rs1788187 chr8:101336099 A/G cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs751728 0.717 rs3763260 chr6:33774070 C/T cg13859433 chr6:33739653 LEMD2 -0.38 -6.72 -0.52 5.77e-10 Crohn's disease; TGCT cis rs42648 0.738 rs10248104 chr7:89895262 C/T cg25739043 chr7:89950458 NA -0.52 -4.68 -0.39 7.51e-6 Homocysteine levels; TGCT cis rs763121 0.925 rs4821815 chr22:39105707 G/A cg06022373 chr22:39101656 GTPBP1 0.76 7.85 0.58 1.7e-12 Menopause (age at onset); TGCT cis rs3771570 1.000 rs62193204 chr2:242315443 A/G cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 4.98 0.41 2.08e-6 Prudent dietary pattern; TGCT cis rs546131 0.928 rs553789 chr11:34827579 G/A cg11058730 chr11:34937778 PDHX;APIP 0.54 4.78 0.39 4.93e-6 Lung disease severity in cystic fibrosis; TGCT cis rs2025751 0.666 rs10214608 chr6:51686253 C/T cg23457901 chr6:52402140 TRAM2 -0.22 -4.52 -0.38 1.43e-5 Intraocular pressure; TGCT cis rs5769765 0.954 rs910799 chr22:50278568 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.42 -6.36 -0.5 3.59e-9 Schizophrenia; TGCT cis rs9952991 0.566 rs579052 chr18:12858610 T/C cg23598886 chr18:12777645 NA 0.57 5.05 0.41 1.51e-6 Inflammatory skin disease; TGCT cis rs637571 0.522 rs503524 chr11:65751764 C/T cg17985854 chr11:65770987 BANF1;EIF1AD 0.21 4.45 0.37 1.9e-5 Eosinophil percentage of white cells; TGCT cis rs2243480 0.901 rs35823062 chr7:65965821 A/G cg20637647 chr7:64974828 NA 0.91 5.37 0.43 3.74e-7 Diabetic kidney disease; TGCT cis rs7959452 0.868 rs10784774 chr12:69737879 C/T cg20891283 chr12:69753455 YEATS4 -0.62 -6.24 -0.49 6.24e-9 Blood protein levels; TGCT cis rs7659604 0.628 rs3828485 chr4:122722368 G/A cg20573242 chr4:122745356 CCNA2 0.64 5.72 0.46 7.42e-8 Type 2 diabetes; TGCT cis rs72945132 0.882 rs12295111 chr11:70131882 C/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs910316 1.000 rs4903279 chr14:75546583 C/T cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.3e-19 Height; TGCT cis rs3091242 0.900 rs1883427 chr1:25744468 C/T cg00786635 chr1:25594202 NA 0.61 6.42 0.5 2.57e-9 Erythrocyte sedimentation rate; TGCT cis rs56104184 0.775 rs117744769 chr19:49402686 G/T cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs5750830 0.620 rs1007337 chr22:39781585 C/T cg02038168 chr22:39784481 NA -0.72 -5.96 -0.47 2.45e-8 Intelligence (multi-trait analysis); TGCT cis rs7662987 0.517 rs1453874 chr4:100022724 G/A cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs2730260 0.578 rs56375711 chr7:158854935 G/A cg27122614 chr7:157913741 PTPRN2 0.45 4.55 0.38 1.24e-5 Myopia (pathological); TGCT cis rs4822044 0.568 rs1883370 chr22:42143740 C/A cg06634786 chr22:41940651 POLR3H 0.83 7.8 0.57 2.19e-12 Cannabis dependence symptom count; TGCT cis rs28595532 0.920 rs115046587 chr4:119779604 T/C cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs9435341 0.762 rs3861909 chr1:107544176 A/G cg09367891 chr1:107599246 PRMT6 -0.68 -5.8 -0.46 5.16e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs6951245 0.580 rs78894484 chr7:1138721 T/G cg23708337 chr7:1209742 NA 0.44 4.87 0.4 3.27e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs1814175 0.817 rs1794162 chr11:49899506 A/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.04 -0.53 1.16e-10 Height; TGCT cis rs478304 0.903 rs495961 chr11:65540886 C/T cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.01e-7 Acne (severe); TGCT cis rs7943191 0.810 rs7942154 chr11:62337163 G/A cg11742103 chr11:62369870 EML3;MTA2 0.53 6.24 0.49 6.4e-9 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs7772486 0.719 rs702317 chr6:146005010 C/T cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs637571 0.510 rs3892696 chr11:65582341 G/C cg04055107 chr11:65626734 MUS81;CFL1 -0.66 -5.74 -0.46 7.01e-8 Eosinophil percentage of white cells; TGCT cis rs10193935 0.901 rs6733464 chr2:42563597 A/G cg27598129 chr2:42591480 NA -0.41 -5.66 -0.45 1e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs4332037 0.802 rs12113633 chr7:1932936 G/A cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT trans rs7618501 0.699 rs1062633 chr3:49924940 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.89 9.73 0.66 5.74e-17 Intelligence (multi-trait analysis); TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg01802117 chr1:53393560 SCP2 -0.45 -5.45 -0.44 2.57e-7 Monocyte count; TGCT cis rs11690935 0.851 rs7581072 chr2:172859849 C/T cg13550731 chr2:172543902 DYNC1I2 -0.9 -8.09 -0.59 4.7e-13 Schizophrenia; TGCT cis rs875971 0.638 rs10278816 chr7:66036987 T/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs7402982 0.647 rs34038360 chr15:99201573 A/C cg03437748 chr15:99193247 IGF1R 0.48 4.84 0.4 3.79e-6 Birth weight; TGCT cis rs7727544 0.678 rs7735891 chr5:131597005 C/T cg24060327 chr5:131705240 SLC22A5 -0.54 -5.29 -0.43 5.45e-7 Blood metabolite levels; TGCT cis rs4273100 0.512 rs7502682 chr17:19295450 G/T cg01534423 chr17:18965556 NA -0.75 -7.83 -0.58 1.83e-12 Schizophrenia; TGCT cis rs10782582 0.632 rs77099976 chr1:76240524 T/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.51 4.59 0.38 1.06e-5 Daytime sleep phenotypes; TGCT cis rs9611519 0.894 rs13053242 chr22:41459486 G/A cg03806693 chr22:41940476 POLR3H -0.67 -6.05 -0.48 1.57e-8 Neuroticism; TGCT cis rs10832963 0.686 rs11024743 chr11:18653712 A/G cg09201001 chr11:18656081 SPTY2D1 1.04 11.77 0.73 6.2e-22 Breast cancer; TGCT cis rs10256972 0.626 rs62433138 chr7:1050877 T/C cg00431813 chr7:1051703 C7orf50 -0.26 -5.81 -0.46 5.03e-8 Longevity;Endometriosis; TGCT cis rs12681287 0.752 rs1436628 chr8:87313345 C/G cg27223183 chr8:87520930 FAM82B 0.83 6.32 0.49 4.32e-9 Caudate activity during reward; TGCT cis rs10504229 1.000 rs73609747 chr8:58189104 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6978712 1.000 rs55921267 chr7:127148361 A/T cg01017541 chr7:127776461 NA 0.76 4.6 0.38 1.01e-5 Medication adherence in chronic diseases; TGCT cis rs13217239 0.574 rs9366680 chr6:27006123 A/T cg26531700 chr6:26746687 NA 0.68 6.91 0.53 2.29e-10 Schizophrenia; TGCT cis rs877529 0.605 rs139412 chr22:39553003 A/G cg18708252 chr22:39545030 CBX7 0.37 5.46 0.44 2.52e-7 Multiple myeloma; TGCT cis rs11574514 1.000 rs117447021 chr16:67669455 G/A cg00545966 chr16:67701244 C16orf86;C16orf48 0.72 4.45 0.37 1.87e-5 Crohn's disease; TGCT cis rs17345786 0.906 rs12638137 chr3:101150964 C/T cg12386194 chr3:101231763 SENP7 0.65 6.39 0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9633740 0.545 rs2343306 chr10:82230146 A/G cg01528321 chr10:82214614 TSPAN14 -0.9 -6.37 -0.5 3.39e-9 Post bronchodilator FEV1; TGCT cis rs5758343 1 rs5758343 chr22:41816652 A/T cg06634786 chr22:41940651 POLR3H 0.94 8.87 0.62 6.61e-15 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7246657 0.943 rs7408563 chr19:37808585 G/C cg18154014 chr19:37997991 ZNF793 0.91 6.09 0.48 1.29e-8 Coronary artery calcification; TGCT cis rs7829975 0.500 rs7841082 chr8:8168987 C/T cg06636001 chr8:8085503 FLJ10661 -0.6 -5.25 -0.43 6.52e-7 Mood instability; TGCT cis rs9972944 0.676 rs9303489 chr17:63784817 T/C cg07283582 chr17:63770753 CCDC46 0.25 4.72 0.39 6.22e-6 Total body bone mineral density; TGCT cis rs4455778 0.659 rs11185626 chr7:49042022 C/T cg26309511 chr7:48887640 NA 0.42 4.98 0.41 2.08e-6 Lung cancer in never smokers; TGCT cis rs6951245 0.872 rs76713558 chr7:1095866 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9467711 0.659 rs3823158 chr6:26463271 T/A cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.5 0.44 2.08e-7 Schizophrenia; TGCT cis rs7010267 0.568 rs2220189 chr8:120007708 C/G cg17171407 chr8:119960777 TNFRSF11B 0.28 5.15 0.42 9.93e-7 Total body bone mineral density (age 45-60); TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg27535305 chr1:53392650 SCP2 -0.29 -6.1 -0.48 1.27e-8 Monocyte count; TGCT cis rs8051431 0.876 rs1559399 chr16:72011261 A/G cg06353428 chr16:71660113 MARVELD3 0.58 4.96 0.41 2.28e-6 LDL cholesterol levels; TGCT cis rs11785400 0.793 rs7459963 chr8:143737129 C/T cg24634471 chr8:143751801 JRK 0.57 5.7 0.46 8.4e-8 Schizophrenia; TGCT cis rs10465746 0.714 rs12141272 chr1:84434517 C/T cg10977910 chr1:84465055 TTLL7 0.69 7.04 0.53 1.14e-10 Obesity-related traits; TGCT cis rs7267979 0.773 rs6132821 chr20:25226192 A/G cg14121845 chr20:25566513 NINL 0.49 4.96 0.41 2.24e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854765 0.856 rs2955382 chr17:17947710 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.34 -0.43 4.31e-7 Total body bone mineral density; TGCT cis rs7020830 0.898 rs997318 chr9:37364094 C/T cg14294708 chr9:37120828 ZCCHC7 1.16 16.05 0.82 4.79e-32 Schizophrenia; TGCT cis rs4077515 0.870 rs10781510 chr9:139279173 G/A cg13741927 chr9:139327495 INPP5E -0.2 -4.67 -0.39 7.59e-6 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs4523957 0.548 rs11869619 chr17:2066150 G/C cg16513277 chr17:2031491 SMG6 -0.21 -4.58 -0.38 1.09e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3764628 0.925 rs752981 chr19:18774790 G/T cg20098710 chr19:19640075 YJEFN3 -0.45 -4.85 -0.4 3.62e-6 Orofacial clefts; TGCT cis rs5750830 0.594 rs6001568 chr22:39775786 G/A cg01416388 chr22:39784598 NA -0.59 -5.85 -0.47 4.11e-8 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.935 rs408768 chr6:145871735 A/G cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg15105969 chr2:36825350 FEZ2 0.58 5.27 0.43 5.88e-7 Height; TGCT cis rs6089829 0.889 rs6090206 chr20:61668363 G/A cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs864643 0.812 rs1513218 chr3:39545588 C/T cg14968361 chr3:39543547 MOBP -0.44 -4.52 -0.38 1.41e-5 Attention deficit hyperactivity disorder; TGCT cis rs2470135 1 rs2470135 chr15:43995789 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.45 4.56 0.38 1.22e-5 Diastolic blood pressure; TGCT cis rs6089584 0.821 rs4925332 chr20:60604639 C/T cg06108461 chr20:60628389 TAF4 -0.65 -9.83 -0.66 3.35e-17 Body mass index; TGCT cis rs3820928 0.874 rs13430941 chr2:227904447 G/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.77 -0.39 5.14e-6 Pulmonary function; TGCT trans rs1005277 0.505 rs200939 chr10:38139483 T/C cg17830980 chr10:43048298 ZNF37B -0.72 -8.22 -0.59 2.33e-13 Extrinsic epigenetic age acceleration; TGCT cis rs2832191 1.000 rs8131214 chr21:30483386 T/G cg24692254 chr21:30365293 RNF160 -0.79 -7.92 -0.58 1.17e-12 Dental caries; TGCT cis rs7666738 0.830 rs2098934 chr4:98992403 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs453301 0.653 rs1045529 chr8:8890098 A/G cg06636001 chr8:8085503 FLJ10661 -0.79 -7.3 -0.55 3.08e-11 Joint mobility (Beighton score); TGCT cis rs4700695 0.686 rs251710 chr5:65347357 G/C cg21114390 chr5:65439923 SFRS12 0.61 4.51 0.38 1.46e-5 Facial morphology (factor 19); TGCT cis rs3806843 0.576 rs246064 chr5:140324309 C/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs1030877 1.000 rs1030877 chr2:105910513 G/A cg02079111 chr2:105885981 TGFBRAP1 0.2 5.93 0.47 2.75e-8 Obesity-related traits; TGCT cis rs854765 0.583 rs11650890 chr17:17790882 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.98 -0.58 8.43e-13 Total body bone mineral density; TGCT cis rs6714788 0.523 rs6542905 chr2:100654707 C/G cg07810366 chr2:100720526 AFF3 -0.36 -5.07 -0.41 1.43e-6 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.600 rs13064780 chr3:49274826 T/G cg03060546 chr3:49711283 APEH 0.53 5.14 0.42 1.05e-6 Menarche (age at onset); TGCT cis rs11191419 1 rs11191419 chr10:104612335 T/A cg04362960 chr10:104952993 NT5C2 0.55 4.74 0.39 5.7e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3806843 0.735 rs801189 chr5:140063091 A/G cg19875535 chr5:140030758 IK -0.36 -6.15 -0.48 9.57e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs7681440 0.904 rs28507349 chr4:90767063 G/A cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs2180341 0.960 rs7773484 chr6:127670779 T/C cg27446573 chr6:127587934 RNF146 1.21 10.87 0.7 9.57e-20 Breast cancer; TGCT cis rs13177918 0.578 rs35919198 chr5:149831991 A/T cg14059543 chr5:149831962 NA -0.69 -9.12 -0.63 1.68e-15 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT trans rs1814175 0.645 rs28447324 chr11:50046629 C/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs4853012 0.941 rs4852329 chr2:74354544 A/G cg20891558 chr2:74357851 NA 0.59 7.39 0.55 1.93e-11 Gestational age at birth (maternal effect); TGCT cis rs7666738 0.830 rs1426666 chr4:99030887 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10465746 0.780 rs2389649 chr1:84379449 C/T cg10977910 chr1:84465055 TTLL7 0.66 6.61 0.51 1.01e-9 Obesity-related traits; TGCT cis rs9650657 0.771 rs4840516 chr8:10667335 C/G cg27411982 chr8:10470053 RP1L1 0.22 4.97 0.41 2.14e-6 Neuroticism; TGCT cis rs7937682 1.000 rs7937682 chr11:111579939 C/G cg09085632 chr11:111637200 PPP2R1B -1.01 -9.96 -0.67 1.61e-17 Primary sclerosing cholangitis; TGCT cis rs12497850 0.931 rs6414613 chr3:49035885 C/T cg06212747 chr3:49208901 KLHDC8B 0.6 5.43 0.44 2.8e-7 Parkinson's disease; TGCT cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs1949733 0.959 rs2688242 chr4:8429943 T/G cg13073564 chr4:8508604 NA -0.48 -5.14 -0.42 1.02e-6 Response to antineoplastic agents; TGCT cis rs7772486 0.790 rs6926657 chr6:146255794 G/A cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs6597334 chr6:8504779 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs250677 0.687 rs3095947 chr5:148436728 T/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs2762353 0.935 rs3757131 chr6:25783909 C/T cg03517284 chr6:25882590 NA 0.5 5.23 0.42 7.13e-7 Blood metabolite levels; TGCT cis rs7956193 0.530 rs1293781 chr12:113463665 A/T cg04001726 chr12:112547043 NAA25 -0.45 -4.49 -0.37 1.58e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs7833790 0.660 rs7839178 chr8:82763479 A/G cg27398817 chr8:82754497 SNX16 0.69 5.52 0.44 1.9e-7 Diastolic blood pressure; TGCT cis rs748404 0.578 rs552701 chr15:43613810 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.82 0.4 4.07e-6 Lung cancer; TGCT trans rs916888 0.773 rs199533 chr17:44828931 G/A cg01341218 chr17:43662625 NA 1.12 9.2 0.64 1.06e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11098499 0.661 rs10015965 chr4:120268237 A/G cg09307838 chr4:120376055 NA 0.56 5.57 0.45 1.51e-7 Corneal astigmatism; TGCT cis rs951366 0.789 rs823137 chr1:205738302 C/T cg26354017 chr1:205819088 PM20D1 0.57 7.01 0.53 1.33e-10 Menarche (age at onset); TGCT cis rs4563143 0.675 rs56293553 chr19:29270455 A/G cg14983838 chr19:29218262 NA 0.83 6.81 0.52 3.8e-10 Methadone dose in opioid dependence; TGCT cis rs11190604 1.000 rs3750630 chr10:102275780 A/G cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.72e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1865760 0.566 rs9379821 chr6:26054268 A/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.1e-11 Height; TGCT cis rs2842992 0.915 rs2758321 chr6:160071611 C/G cg11366901 chr6:160182831 ACAT2 0.96 6.29 0.49 5.04e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs9653442 0.545 rs1821827 chr2:100764717 T/C cg22139774 chr2:100720529 AFF3 -0.38 -5.98 -0.47 2.19e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11971779 0.793 rs9632774 chr7:139137562 C/T cg07862535 chr7:139043722 LUC7L2 0.63 4.65 0.39 8.25e-6 Diisocyanate-induced asthma; TGCT cis rs903263 0.582 rs11163898 chr1:84547271 C/T cg09664975 chr1:84543551 PRKACB 0.5 4.87 0.4 3.39e-6 Breast cancer (male); TGCT cis rs7267979 1.000 rs2500448 chr20:25404027 A/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7267979 0.873 rs6037062 chr20:25202892 G/A cg14121845 chr20:25566513 NINL 0.45 5.01 0.41 1.81e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2730245 0.545 rs2788472 chr7:158649304 T/C cg11984989 chr7:158649758 WDR60 1.04 9.33 0.64 5.3e-16 Height; TGCT cis rs7909670 0.716 rs10906245 chr10:12928438 T/C cg23097415 chr10:13391488 SEPHS1 0.49 4.62 0.38 9.32e-6 Height; TGCT cis rs6912958 0.547 rs451089 chr6:88041859 A/G cg04972856 chr6:88032051 C6orf162;GJB7 0.41 4.81 0.4 4.22e-6 Monocyte percentage of white cells; TGCT cis rs875971 0.577 rs34888281 chr7:65585771 C/T cg00343986 chr7:65444356 GUSB -0.23 -4.9 -0.4 2.87e-6 Aortic root size; TGCT cis rs854765 0.654 rs9911281 chr17:17762457 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.65 -0.57 4.87e-12 Total body bone mineral density; TGCT cis rs2677744 0.626 rs12915155 chr15:91490894 G/T cg23684204 chr15:91497937 RCCD1 0.36 5.37 0.43 3.79e-7 Attention deficit hyperactivity disorder; TGCT cis rs1008375 0.966 rs6825133 chr4:17577776 C/T cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9534288 0.730 rs7985754 chr13:46581287 G/A cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs453301 0.507 rs2929306 chr8:9084909 C/T cg06636001 chr8:8085503 FLJ10661 -0.56 -5.06 -0.41 1.46e-6 Joint mobility (Beighton score); TGCT cis rs981844 0.857 rs72731698 chr4:154716353 T/C cg14289246 chr4:154710475 SFRP2 1.05 8.88 0.62 6.23e-15 Response to statins (LDL cholesterol change); TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg23131131 chr22:24373011 LOC391322 -0.81 -9.08 -0.63 2.09e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836974 0.899 rs35774464 chr21:40580169 G/A cg17971929 chr21:40555470 PSMG1 0.95 9.07 0.63 2.19e-15 Cognitive function; TGCT cis rs2816958 0.803 rs2737685 chr1:200093351 C/T cg07971716 chr1:199773294 NA 0.46 4.52 0.38 1.45e-5 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs2050392 0.624 rs2489842 chr10:30721991 T/C cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs1997103 0.911 rs11238361 chr7:55395981 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.63 6.79 0.52 4.17e-10 Height; TGCT trans rs4332037 0.950 rs11771828 chr7:1941003 T/C cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs35146811 0.586 rs12705067 chr7:99594726 T/C cg13334819 chr7:99746414 C7orf59 -0.65 -5.76 -0.46 6.21e-8 Coronary artery disease; TGCT cis rs3027009 0.881 rs3026942 chr1:159131857 A/G cg24432768 chr1:158149974 CD1D -0.48 -4.62 -0.38 9.29e-6 Lean body mass and age at menarche (combined); TGCT cis rs8014204 0.570 rs7147721 chr14:75186010 A/G cg06637938 chr14:75390232 RPS6KL1 0.74 7.31 0.55 2.81e-11 Caffeine consumption; TGCT cis rs4803468 0.967 rs3786553 chr19:41902746 T/G cg09537434 chr19:41945824 ATP5SL -0.91 -10.71 -0.69 2.37e-19 Height; TGCT cis rs35146811 0.735 rs6465766 chr7:99785671 A/G cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs7552404 0.590 rs1565717 chr1:76320441 T/C cg10523679 chr1:76189770 ACADM -0.67 -6.36 -0.5 3.5e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs986417 0.818 rs1010051 chr14:61002988 G/C cg27398547 chr14:60952738 C14orf39 1.49 10.43 0.68 1.12e-18 Gut microbiota (bacterial taxa); TGCT cis rs2439831 0.867 rs2447211 chr15:43936351 G/A cg19166733 chr15:44192098 FRMD5 -0.24 -4.89 -0.4 3.08e-6 Lung cancer in ever smokers; TGCT cis rs7949030 0.591 rs11231156 chr11:62366454 G/A cg13298116 chr11:62369859 EML3;MTA2 0.64 9.48 0.65 2.35e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1609391 0.561 rs9817967 chr3:136629490 G/A cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs7528684 0.902 rs2210912 chr1:157668701 A/C cg17134153 chr1:157670328 FCRL3 -0.25 -4.73 -0.39 5.9e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs950169 0.595 rs11631921 chr15:85143277 G/A cg11189052 chr15:85197271 WDR73 0.86 7.28 0.55 3.31e-11 Schizophrenia; TGCT cis rs2777491 0.957 rs3743038 chr15:41694743 C/T cg18705301 chr15:41695430 NDUFAF1 -0.75 -10.81 -0.7 1.35e-19 Ulcerative colitis; TGCT cis rs3015497 0.616 rs4901043 chr14:51083594 C/T cg04730355 chr14:51134070 SAV1 0.62 5.98 0.47 2.23e-8 Mean platelet volume; TGCT cis rs60871478 0.898 rs35928069 chr7:823067 G/C cg15782153 chr7:917662 C7orf20 -0.51 -4.58 -0.38 1.1e-5 Cerebrospinal P-tau181p levels; TGCT cis rs2153535 0.601 rs1855768 chr6:8472969 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1538970 0.961 rs4660854 chr1:45854087 A/T cg05343316 chr1:45956843 TESK2 0.69 5.25 0.43 6.49e-7 Platelet count; TGCT cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg16145915 chr7:1198662 ZFAND2A -0.62 -8.8 -0.62 9.71e-15 Longevity;Endometriosis; TGCT cis rs9894429 0.621 rs7502337 chr17:79588470 T/C cg18240062 chr17:79603768 NPLOC4 0.56 4.94 0.41 2.5e-6 Eye color traits; TGCT cis rs228437 0.586 rs2207421 chr6:134913417 A/C cg09872934 chr6:134495829 SGK1 0.55 4.75 0.39 5.62e-6 Melanoma; TGCT cis rs7582180 0.629 rs7597615 chr2:100954828 T/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs1023500 0.551 rs2859438 chr22:42466980 A/T cg15557168 chr22:42548783 NA -0.22 -5.58 -0.45 1.47e-7 Schizophrenia; TGCT cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs6500602 0.653 rs4786487 chr16:4440397 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.3 -4.9 -0.4 2.91e-6 Schizophrenia; TGCT cis rs2486288 0.656 rs11632920 chr15:45551264 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.57 -0.45 1.51e-7 Glomerular filtration rate; TGCT cis rs2228479 0.702 rs62052710 chr16:89854893 C/T cg06558623 chr16:89946397 TCF25 0.47 4.58 0.38 1.14e-5 Skin colour saturation; TGCT cis rs78487399 0.808 rs7573500 chr2:43685625 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.77 0.39 5.16e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2468186 0.710 rs2450063 chr8:120097576 G/A cg02248809 chr8:120845432 TAF2 -0.43 -4.55 -0.38 1.27e-5 Osteoprotegerin levels; TGCT cis rs12210905 0.920 rs77380818 chr6:27305498 G/A cg08851530 chr6:28072375 NA 1.32 5.79 0.46 5.48e-8 Hip circumference adjusted for BMI; TGCT cis rs1218582 0.803 rs7531728 chr1:154840516 C/A cg24250549 chr1:154909240 PMVK 0.55 5.34 0.43 4.31e-7 Prostate cancer; TGCT cis rs2721195 0.816 rs4251689 chr8:145741130 C/T cg15320075 chr8:145703422 NA 0.7 7.03 0.53 1.2e-10 Age at first birth; TGCT cis rs1577917 1.000 rs7760207 chr6:86721700 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs12989701 1.000 rs13004848 chr2:127887560 C/T cg08168897 chr2:127865431 BIN1 -0.59 -5.76 -0.46 6.14e-8 Alzheimer's disease (late onset); TGCT cis rs950776 0.518 rs1979907 chr15:78842239 T/C cg06917634 chr15:78832804 PSMA4 -0.95 -9.52 -0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs9527 0.662 rs4919687 chr10:104595248 G/A cg04362960 chr10:104952993 NT5C2 0.62 5.39 0.44 3.37e-7 Arsenic metabolism; TGCT cis rs5769707 0.632 rs5770601 chr22:50021903 A/G cg05373962 chr22:49881684 NA -0.3 -5.02 -0.41 1.78e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9311474 0.508 rs11718420 chr3:52611413 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs4878497 0.544 rs3205166 chr9:32459450 G/T cg14213824 chr9:33265091 SUGT1P1;BAG1;CHMP5 -0.47 -4.55 -0.38 1.24e-5 Inflammatory skin disease; TGCT cis rs1371867 0.846 rs1660338 chr8:101242757 C/G cg06636551 chr8:101224915 SPAG1 -0.44 -6.11 -0.48 1.19e-8 Atrioventricular conduction; TGCT cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs6866344 0.697 rs72812613 chr5:178135257 G/A cg03877680 chr5:178157825 ZNF354A 0.75 6.02 0.48 1.79e-8 Neutrophil percentage of white cells; TGCT cis rs6665290 0.935 rs12403236 chr1:227196502 C/G cg10327440 chr1:227177885 CDC42BPA -1.0 -20.65 -0.88 6.07e-42 Myeloid white cell count; TGCT cis rs7267979 0.899 rs442834 chr20:25458096 A/G cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.683 rs113492050 chr8:58130046 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs79349575 0.783 rs55771415 chr17:46999937 C/T cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs6598955 0.585 rs12138111 chr1:26590432 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs2839186 0.721 rs13051200 chr21:47701693 A/T cg13732083 chr21:47605072 C21orf56 0.34 4.52 0.38 1.44e-5 Testicular germ cell tumor; TGCT cis rs12367572 1.000 rs12822444 chr12:45276677 G/A cg04608330 chr12:45269318 NELL2 -0.65 -6.63 -0.51 9.33e-10 Gut microbiome composition (summer); TGCT cis rs10832169 0.967 rs11023065 chr11:14068729 C/G cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs7312933 0.531 rs2708059 chr12:42851008 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.56 -5.53 -0.44 1.8e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT trans rs7819412 0.668 rs4841507 chr8:11046394 C/G cg15556689 chr8:8085844 FLJ10661 -0.81 -7.6 -0.56 6.26e-12 Triglycerides; TGCT cis rs1867631 0.876 rs10889637 chr1:67097465 C/T cg13052034 chr1:66999238 SGIP1 0.57 4.75 0.39 5.53e-6 Menopause (age at onset); TGCT cis rs9810089 0.749 rs664088 chr3:136036986 T/C cg12473912 chr3:136751656 NA 0.35 4.99 0.41 2.01e-6 Gestational age at birth (child effect); TGCT cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs244731 1.000 rs244731 chr5:176539679 C/T cg06060754 chr5:176797920 RGS14 0.39 5.45 0.44 2.56e-7 Urate levels in lean individuals; TGCT cis rs7909074 0.966 rs4245614 chr10:45397007 C/T cg05187965 chr10:45406764 TMEM72 -0.24 -5.07 -0.41 1.42e-6 Mean corpuscular volume; TGCT cis rs3935685 0.874 rs36058724 chr15:78006745 C/A cg03457338 chr15:78040120 NA -0.22 -5.74 -0.46 6.9e-8 Intelligence (multi-trait analysis); TGCT cis rs7819412 0.837 rs17724467 chr8:10975682 C/G cg21775007 chr8:11205619 TDH -0.52 -4.99 -0.41 1.98e-6 Triglycerides; TGCT cis rs3772130 0.962 rs35679661 chr3:121484763 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs2841277 0.741 rs9672139 chr14:105408182 T/G cg21017887 chr14:105400489 NA 0.34 4.87 0.4 3.36e-6 Rheumatoid arthritis; TGCT cis rs10504229 0.683 rs56196593 chr8:58141898 G/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.764 rs76635693 chr6:145834070 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg02953382 chr22:24373134 LOC391322 -0.77 -7.9 -0.58 1.27e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs931812 0.895 rs965625 chr8:101909749 T/C cg20993868 chr7:22813445 NA 0.4 8.94 0.63 4.62e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT trans rs7618501 0.633 rs6772095 chr3:49978069 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.92 0.67 1.95e-17 Intelligence (multi-trait analysis); TGCT cis rs854765 0.583 rs4534911 chr17:17852330 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.76 7.88 0.58 1.41e-12 Total body bone mineral density; TGCT cis rs1153858 1.000 rs7181167 chr15:45686236 C/G cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT trans rs11992162 0.597 rs7824564 chr8:11780180 A/G cg15556689 chr8:8085844 FLJ10661 -0.79 -6.77 -0.52 4.69e-10 Monocyte count; TGCT cis rs1933488 1.000 rs1442744 chr6:153441733 G/C cg24028809 chr6:153414101 RGS17 0.2 4.5 0.38 1.51e-5 Prostate cancer; TGCT trans rs9364554 0.506 rs3125055 chr6:160736787 A/T cg26000619 chr19:2251067 AMH -0.86 -6.66 -0.51 7.77e-10 Prostate cancer (SNP x SNP interaction);Prostate cancer; TGCT cis rs6459788 0.502 rs9692347 chr7:157232659 C/T cg06271696 chr7:157225062 NA -0.35 -6.37 -0.5 3.36e-9 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs137699 1.000 rs2413588 chr22:39755175 A/G cg11247378 chr22:39784982 NA -0.46 -5.09 -0.42 1.28e-6 IgG glycosylation; TGCT cis rs4727027 0.933 rs757738 chr7:148872351 T/G cg23583168 chr7:148888333 NA -0.75 -9.84 -0.66 3.1e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs931812 0.757 rs4734015 chr8:101909258 C/G cg20993868 chr7:22813445 NA 0.33 6.77 0.52 4.48e-10 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs7264396 0.635 rs6058344 chr20:34475038 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs4665809 0.590 rs4665313 chr2:26415897 A/G cg22920501 chr2:26401640 FAM59B -0.79 -6.36 -0.5 3.58e-9 Gut microbiome composition (summer); TGCT cis rs11031096 0.542 rs7924984 chr11:3974588 C/T cg08557956 chr11:4115526 RRM1 -0.52 -4.72 -0.39 6.28e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs10504229 0.953 rs6990806 chr8:58183113 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1580019 0.587 rs7805311 chr7:32558302 A/G cg06627557 chr7:32535165 LSM5;AVL9 -1.1 -14.09 -0.78 1.65e-27 Cognitive ability; TGCT cis rs174601 0.833 rs174541 chr11:61565908 T/C cg01500311 chr11:61656094 FADS3 -0.31 -5.16 -0.42 9.37e-7 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs10504229 0.953 rs59034808 chr8:58185337 T/C cg22535103 chr8:58192502 C8orf71 -0.37 -4.73 -0.39 6.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs921968 0.608 rs832817 chr2:219358603 C/T cg02176678 chr2:219576539 TTLL4 0.44 6.33 0.49 4.17e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg01411255 chr17:61851458 DDX42;CCDC47 0.99 11.05 0.7 3.51e-20 Height; TGCT cis rs12220238 0.915 rs11000987 chr10:76073265 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.28 0.49 5.18e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9926296 0.585 rs8045232 chr16:89857548 A/G cg27121462 chr16:89883253 FANCA 0.83 9.35 0.64 4.78e-16 Vitiligo; TGCT cis rs644799 0.603 rs1255180 chr11:95472134 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.5 4.8 0.4 4.53e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7674212 0.507 rs223413 chr4:103732866 A/G cg16532752 chr4:104119610 CENPE 0.61 5.1 0.42 1.26e-6 Type 2 diabetes; TGCT cis rs7216064 1.000 rs6504542 chr17:65836642 T/C cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs35306767 0.903 rs35968821 chr10:910225 A/G cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs8177253 0.798 rs9871148 chr3:133507509 T/C cg08048268 chr3:133502702 NA -0.67 -10.27 -0.68 2.75e-18 Iron status biomarkers; TGCT cis rs2299587 0.689 rs12546237 chr8:17797055 A/G cg01800426 chr8:17659068 MTUS1 -0.65 -5.68 -0.45 9.22e-8 Economic and political preferences; TGCT cis rs35306767 0.953 rs34405399 chr10:981015 G/A cg18964960 chr10:1102726 WDR37 0.56 4.58 0.38 1.12e-5 Eosinophil percentage of granulocytes; TGCT cis rs910316 1.000 rs12435391 chr14:75601737 A/G cg11812906 chr14:75593930 NEK9 0.73 7.18 0.54 5.79e-11 Height; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg24846343 chr22:24311635 DDTL 0.23 5.74 0.46 6.85e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs909674 0.734 rs5757675 chr22:39838892 G/T cg05872129 chr22:39784769 NA -0.98 -9.83 -0.66 3.19e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs986417 1.000 rs1268621 chr14:60921571 G/A cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs929354 0.713 rs3802130 chr7:156965237 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs7017914 0.837 rs2639952 chr8:71925730 T/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.21e-6 Bone mineral density; TGCT cis rs35146811 0.735 rs1061230 chr7:99807265 G/A cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs6893807 0.778 rs35991856 chr5:87968347 C/A cg24804195 chr5:87968844 LOC645323 0.77 4.58 0.38 1.11e-5 Body mass index; TGCT cis rs10782582 0.593 rs79552201 chr1:76215497 A/T cg22875332 chr1:76189707 ACADM -0.49 -5.39 -0.44 3.35e-7 Daytime sleep phenotypes; TGCT cis rs1865760 0.566 rs1971509 chr6:26085777 T/C cg17042849 chr6:26104293 HIST1H4C -0.63 -5.47 -0.44 2.43e-7 Height; TGCT cis rs12681288 0.862 rs935821 chr8:1022455 G/A cg08872321 chr8:1308229 NA -0.25 -4.67 -0.39 7.63e-6 Schizophrenia; TGCT cis rs6840360 1.000 rs1896883 chr4:152595373 C/T cg17479576 chr4:152424074 FAM160A1 0.51 5.46 0.44 2.5e-7 Intelligence (multi-trait analysis); TGCT cis rs2692947 0.644 rs772178 chr2:96963684 C/T cg22654517 chr2:96458247 NA -0.21 -4.75 -0.39 5.54e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs3785574 0.927 rs2008018 chr17:61954471 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.98 10.69 0.69 2.69e-19 Height; TGCT cis rs6964587 1.000 rs10281556 chr7:91660053 C/T cg22709100 chr7:91322751 NA -0.27 -4.5 -0.37 1.55e-5 Breast cancer; TGCT trans rs9951602 0.512 rs4799245 chr18:76653397 T/C cg02800362 chr5:177631904 HNRNPAB 1.14 12.9 0.76 1.17e-24 Obesity-related traits; TGCT cis rs1801251 1.000 rs2044449 chr2:233718808 G/A cg08000102 chr2:233561755 GIGYF2 -0.63 -6.41 -0.5 2.72e-9 Coronary artery disease; TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg16325326 chr1:53192061 ZYG11B 0.59 6.41 0.5 2.81e-9 Monocyte count; TGCT cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg10263370 chr3:44754102 ZNF502 -0.47 -5.47 -0.44 2.4e-7 Depressive symptoms; TGCT cis rs9409154 1.000 rs9408867 chr9:118209531 T/A cg14094498 chr9:119000864 PAPPA 0.23 4.59 0.38 1.05e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs7666738 0.680 rs11726233 chr4:99079773 G/A cg17366294 chr4:99064904 C4orf37 0.68 6.58 0.51 1.19e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.72 -0.39 6.2e-6 Coronary artery disease; TGCT cis rs7611238 0.583 rs58178384 chr3:195130096 G/A cg27323046 chr3:195102265 ACAP2 0.36 4.89 0.4 3.1e-6 Body mass index; TGCT cis rs3935685 0.874 rs36058724 chr15:78006745 C/A cg25212270 chr15:78015279 NA 0.26 5.45 0.44 2.64e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.546 rs5758430 chr22:42109844 G/T cg17554472 chr22:41940697 POLR3H 0.48 5.17 0.42 9e-7 Vitiligo; TGCT cis rs1577917 1.000 rs7756203 chr6:86627707 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs7772486 0.521 rs9485017 chr6:146023326 C/T cg23711669 chr6:146136114 FBXO30 0.68 6.38 0.5 3.21e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9393692 0.627 rs1059486 chr6:26200083 A/G cg05868516 chr6:26286170 HIST1H4H 0.52 5.18 0.42 8.72e-7 Educational attainment; TGCT cis rs35306767 0.761 rs12359796 chr10:1021479 G/C cg18964960 chr10:1102726 WDR37 0.74 5.25 0.43 6.39e-7 Eosinophil percentage of granulocytes; TGCT cis rs3125734 0.660 rs10733769 chr10:63974255 G/T cg19640130 chr10:64028056 RTKN2 -0.41 -5.19 -0.42 8.51e-7 Rheumatoid arthritis; TGCT cis rs6500602 0.855 rs1139652 chr16:4476089 T/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.44 5.42 0.44 3.01e-7 Schizophrenia; TGCT cis rs7208859 0.573 rs216442 chr17:28931197 T/G cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1692580 0.840 rs263526 chr1:2173504 T/C cg21194808 chr1:2205498 SKI 0.3 5.69 0.46 8.51e-8 Coronary artery disease; TGCT cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs9660992 0.573 rs1172159 chr1:205207512 T/C cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs7095607 0.813 rs10997973 chr10:69930054 T/C cg18986048 chr10:69913749 MYPN 0.44 5.02 0.41 1.72e-6 Lung function (FVC); TGCT cis rs71636778 0.509 rs34976021 chr1:27298564 C/A cg23921621 chr1:27994728 IFI6 -0.43 -4.66 -0.39 8.14e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs9914988 0.943 rs34693224 chr17:27079555 C/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs514406 0.679 rs960570 chr1:53237763 A/G cg25767906 chr1:53392781 SCP2 0.6 7.21 0.54 4.89e-11 Monocyte count; TGCT cis rs3749237 0.964 rs62260719 chr3:49852419 G/A cg07636037 chr3:49044803 WDR6 0.61 5.36 0.43 3.9e-7 Resting heart rate; TGCT cis rs1580019 0.885 rs3801331 chr7:32497039 A/G cg06627557 chr7:32535165 LSM5;AVL9 -0.85 -7.93 -0.58 1.08e-12 Cognitive ability; TGCT cis rs28386778 0.897 rs2854221 chr17:61941445 G/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs11785400 0.762 rs4401833 chr8:143739731 A/T cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs9372253 0.678 rs9487392 chr6:110708626 C/T cg00083206 chr6:110721305 DDO 0.38 5.51 0.44 1.94e-7 Platelet distribution width; TGCT cis rs3096299 0.719 rs2965945 chr16:89514017 T/C cg06640241 chr16:89574553 SPG7 0.77 8.57 0.61 3.4e-14 Multiple myeloma (IgH translocation); TGCT cis rs7178572 0.568 rs11072643 chr15:77415508 T/A cg22256960 chr15:77711686 NA 0.85 8.6 0.61 2.85e-14 Type 2 diabetes; TGCT cis rs4072705 0.615 rs6478666 chr9:127249343 C/G cg13476313 chr9:127244764 NR5A1 -0.3 -5.01 -0.41 1.81e-6 Menarche (age at onset); TGCT cis rs797680 0.964 rs624131 chr1:93683210 A/G cg17826107 chr1:92977322 EVI5 0.24 5.3 0.43 5.16e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs9951602 0.512 rs4799249 chr18:76654370 A/G cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs9916302 0.904 rs11869109 chr17:37518205 G/T cg07936489 chr17:37558343 FBXL20 0.65 5.09 0.42 1.3e-6 Glomerular filtration rate (creatinine); TGCT cis rs2204008 0.714 rs11520135 chr12:38114863 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.19 0.42 8.26e-7 Bladder cancer; TGCT cis rs6964587 1.000 rs6976122 chr7:91610962 T/C cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs7267979 0.966 rs416745 chr20:25438868 T/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7772486 0.817 rs2144477 chr6:146406248 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9436747 0.680 rs1171268 chr1:65996166 G/T cg14976592 chr1:65886160 LEPROT;LEPR -0.5 -4.69 -0.39 7.14e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs12762955 0.507 rs7070724 chr10:1040138 C/T cg26597838 chr10:835615 NA -0.49 -6.41 -0.5 2.76e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs10114408 0.959 rs57222595 chr9:96663077 G/A cg13679303 chr9:96623674 NA -0.36 -4.66 -0.39 8e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs904251 0.772 rs2252920 chr6:37418327 A/G cg08126542 chr6:37504118 NA -0.39 -4.49 -0.37 1.6e-5 Cognitive performance; TGCT cis rs13242816 1.000 rs56298491 chr7:116116687 C/T cg16553024 chr7:116138462 CAV2 -0.45 -4.75 -0.39 5.64e-6 P wave duration; TGCT cis rs9818758 0.607 rs9311439 chr3:49310408 A/G cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs1552244 0.554 rs6762702 chr3:10055789 G/A cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs6977940 0.818 rs73033457 chr7:2899235 C/A cg19731401 chr7:2775893 GNA12 0.37 4.49 0.37 1.61e-5 White matter integrity; TGCT cis rs4803468 1.000 rs55986560 chr19:41939835 C/T cg09537434 chr19:41945824 ATP5SL 0.92 10.44 0.68 1.1e-18 Height; TGCT trans rs17685 0.753 rs1574107 chr7:75685047 A/C cg19862616 chr7:65841803 NCRNA00174 0.5 8.31 0.6 1.45e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs9399135 0.967 rs2297338 chr6:135375762 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs9341808 0.591 rs6454147 chr6:80916328 G/A cg08355045 chr6:80787529 NA 0.31 5.17 0.42 9e-7 Sitting height ratio; TGCT trans rs4332037 0.851 rs73050128 chr7:1961882 C/A cg10840412 chr1:235813424 GNG4 1.05 8.44 0.6 7.18e-14 Bipolar disorder; TGCT cis rs4665809 1.000 rs2384321 chr2:26290054 A/G cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2197308 0.765 rs11182481 chr12:37926019 T/C cg13010199 chr12:38710504 ALG10B 0.63 5.2 0.42 7.87e-7 Morning vs. evening chronotype; TGCT cis rs11190604 1.000 rs4604805 chr10:102261409 C/G cg16342193 chr10:102329863 NA -0.4 -5.17 -0.42 9.14e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3820928 0.874 rs2276593 chr2:227898434 A/G cg11843606 chr2:227700838 RHBDD1 0.52 4.62 0.38 9.37e-6 Pulmonary function; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg04234412 chr22:24373322 LOC391322 -0.91 -10.46 -0.68 9.75e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2180341 0.574 rs13192350 chr6:127677762 G/T cg27446573 chr6:127587934 RNF146 0.67 5.92 0.47 2.88e-8 Breast cancer; TGCT cis rs10504229 0.906 rs73607868 chr8:58172482 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs8177253 1.000 rs8177272 chr3:133482870 C/T cg08439880 chr3:133502540 NA -0.32 -5.89 -0.47 3.39e-8 Iron status biomarkers; TGCT cis rs6912958 0.678 rs9450733 chr6:88250081 C/T cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs11031096 0.655 rs56172516 chr11:4182004 G/T cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7772486 0.713 rs2328704 chr6:146020494 T/C cg23711669 chr6:146136114 FBXO30 -0.81 -8.65 -0.61 2.25e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs7017914 0.934 rs62530772 chr8:71601541 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs7662987 0.517 rs2602881 chr4:100040695 A/G cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs6693567 0.565 rs1260457 chr1:150347374 G/A cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs6809651 0.524 rs6444105 chr3:185811301 C/T cg00760338 chr3:185826511 ETV5 -0.78 -6.56 -0.51 1.32e-9 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs10504229 1.000 rs17216620 chr8:58169412 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs35883536 0.513 rs4907910 chr1:101013277 T/A cg06223162 chr1:101003688 GPR88 0.42 8.13 0.59 3.84e-13 Monocyte count; TGCT cis rs6840360 0.642 rs2053566 chr4:152445831 A/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.569 rs75466737 chr8:58055034 A/G cg08280861 chr8:58055591 NA 0.51 5.73 0.46 7.17e-8 Developmental language disorder (linguistic errors); TGCT cis rs902774 0.554 rs4919749 chr12:53358034 C/T cg16329197 chr12:53359506 NA -0.52 -7.63 -0.57 5.32e-12 Prostate cancer; TGCT cis rs12369635 1.000 rs9645723 chr12:129554501 C/T cg01909103 chr12:129572610 TMEM132D -0.64 -4.63 -0.38 9.16e-6 Schizophrenia (inflammation and infection response interaction); TGCT cis rs1008375 1.000 rs56308330 chr4:17643050 G/A cg16339924 chr4:17578868 LAP3 0.61 5.19 0.42 8.41e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs2842992 0.662 rs2273826 chr6:160211421 A/G cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs3812831 0.629 rs7318527 chr13:114946956 C/T cg15513719 chr13:114904418 NA 0.38 4.68 0.39 7.53e-6 Schizophrenia; TGCT cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg24675658 chr1:53192096 ZYG11B 0.9 12.17 0.74 6.61e-23 Monocyte count; TGCT cis rs6061231 0.798 rs2427308 chr20:60969451 C/T cg24112000 chr20:60950667 NA -0.4 -5.06 -0.41 1.44e-6 Colorectal cancer; TGCT cis rs7246657 0.943 rs10417503 chr19:37842735 T/C cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs3087591 0.919 rs2952993 chr17:29539998 G/A cg24425628 chr17:29625626 OMG;NF1 0.42 6.22 0.49 7.06e-9 Hip circumference; TGCT cis rs9436747 0.680 rs2154381 chr1:65995701 C/T cg14976592 chr1:65886160 LEPROT;LEPR -0.49 -4.52 -0.38 1.42e-5 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs2469997 1.000 rs2447183 chr8:120352978 A/G cg00681363 chr8:120844660 TAF2 0.65 4.52 0.38 1.45e-5 Hypertension (SNP x SNP interaction); TGCT cis rs62380364 0.602 rs588282 chr5:88032651 G/T cg24804195 chr5:87968844 LOC645323 -0.59 -5.9 -0.47 3.31e-8 Intelligence (multi-trait analysis); TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg19536664 chr17:6899085 ALOX12 0.39 6.1 0.48 1.23e-8 Tonsillectomy; TGCT cis rs4595586 0.967 rs1400280 chr12:39241240 A/G cg10518543 chr12:38710700 ALG10B -0.52 -5.37 -0.43 3.7e-7 Morning vs. evening chronotype; TGCT cis rs707040 1.000 rs6760854 chr2:155235144 C/T cg18104148 chr2:154337490 NA 0.19 4.56 0.38 1.2e-5 Sudden cardiac arrest; TGCT cis rs7666738 0.822 rs979946 chr4:98921235 C/A cg18180107 chr4:99064573 C4orf37 0.56 5.13 0.42 1.08e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7598759 0.527 rs7571691 chr2:232369401 C/T cg19187155 chr2:232395269 NMUR1 0.47 5.43 0.44 2.91e-7 Noise-induced hearing loss; TGCT cis rs16958440 0.867 rs28578518 chr18:44687548 A/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs2019137 0.967 rs902695 chr2:113955074 G/A cg27425262 chr2:113953981 PSD4;LOC440839 -0.53 -8.24 -0.59 2.08e-13 Lymphocyte counts; TGCT cis rs10114408 0.959 rs1933675 chr9:96655212 C/T cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 7e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg21724239 chr8:58056113 NA 0.4 5.01 0.41 1.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs57590327 0.503 rs9874464 chr3:81505488 C/G cg07356753 chr3:81810745 GBE1 -0.59 -5.03 -0.41 1.67e-6 Extraversion; TGCT cis rs6665290 0.904 rs2297416 chr1:227172935 C/G cg10327440 chr1:227177885 CDC42BPA -1.0 -19.47 -0.87 1.62e-39 Myeloid white cell count; TGCT cis rs55823223 0.646 rs74410877 chr17:73832384 C/T cg10935138 chr17:73851978 WBP2 0.91 5.54 0.45 1.72e-7 Psoriasis; TGCT cis rs2688608 0.592 rs12253429 chr10:75496161 C/G cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs2836974 0.681 rs8128827 chr21:40710547 C/T cg06238570 chr21:40685208 BRWD1 0.67 5.95 0.47 2.5e-8 Cognitive function; TGCT cis rs13217239 0.646 rs12209886 chr6:26984757 G/A cg02458000 chr6:26745757 NA 0.5 4.61 0.38 9.84e-6 Schizophrenia; TGCT cis rs9300255 0.602 rs1727315 chr12:123638930 A/G cg00376283 chr12:123451042 ABCB9 -0.67 -5.27 -0.43 5.78e-7 Neutrophil percentage of white cells; TGCT cis rs1348850 0.958 rs11684320 chr2:178456346 T/C cg22681709 chr2:178499509 PDE11A -0.4 -4.97 -0.41 2.18e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs7772486 0.875 rs11155452 chr6:146424631 C/T cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs3749237 0.615 rs11130202 chr3:49566715 C/T cg07636037 chr3:49044803 WDR6 0.64 6.11 0.48 1.18e-8 Resting heart rate; TGCT cis rs6964587 0.655 rs6465351 chr7:91773213 T/C cg17063962 chr7:91808500 NA 0.74 6.94 0.53 1.93e-10 Breast cancer; TGCT cis rs7107174 0.581 rs11237485 chr11:78126011 G/A cg12700464 chr11:78128424 GAB2 -0.66 -4.45 -0.37 1.9e-5 Testicular germ cell tumor; TGCT cis rs2739330 0.964 rs2739338 chr22:24297130 T/C cg12419862 chr22:24373484 LOC391322 -0.8 -8.67 -0.61 1.97e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs1864729 1.000 rs2439702 chr8:98272647 C/T cg08679828 chr8:102218111 ZNF706 -1.09 -7.6 -0.56 6.34e-12 Estradiol plasma levels (breast cancer); TGCT cis rs7940866 0.834 rs1594821 chr11:130835883 C/T cg12179176 chr11:130786555 SNX19 0.66 6.07 0.48 1.46e-8 Schizophrenia; TGCT cis rs17376456 0.825 rs67328989 chr5:93243133 T/A cg09848695 chr5:92956644 FAM172A;MIR2277 0.74 4.89 0.4 3.12e-6 Diabetic retinopathy; TGCT cis rs4499344 0.633 rs411328 chr19:33140178 T/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.96 0.63 4.15e-15 Mean platelet volume; TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg06873352 chr17:61820015 STRADA -0.53 -5.99 -0.47 2.14e-8 Prudent dietary pattern; TGCT cis rs939574 1.000 rs6712442 chr2:220117333 T/G cg00496455 chr2:220118770 TUBA4A;TUBA4B -1.05 -6.46 -0.5 2.12e-9 Platelet distribution width; TGCT cis rs8180040 1.000 rs11130127 chr3:47398793 C/G cg27129171 chr3:47204927 SETD2 -0.7 -8.63 -0.61 2.53e-14 Colorectal cancer; TGCT cis rs858239 0.602 rs6953996 chr7:23175946 A/G cg05602783 chr7:23145260 KLHL7 -0.67 -5.71 -0.46 8.04e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs74233809 1.000 rs12219027 chr10:104811203 T/C cg05855489 chr10:104503620 C10orf26 0.76 4.53 0.38 1.36e-5 Birth weight; TGCT cis rs13256369 1.000 rs13256369 chr8:8577379 T/C cg17143192 chr8:8559678 CLDN23 0.62 5.87 0.47 3.67e-8 Obesity-related traits; TGCT trans rs1814175 0.817 rs4084376 chr11:49831160 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs926938 0.563 rs360652 chr1:115445478 C/T cg12756093 chr1:115239321 AMPD1 0.4 6.33 0.49 4.02e-9 Autism; TGCT cis rs7611238 0.560 rs9855453 chr3:195067232 G/A cg27323046 chr3:195102265 ACAP2 0.35 4.82 0.4 4.11e-6 Body mass index; TGCT cis rs7178572 0.568 rs28584877 chr15:77599003 C/A cg15453836 chr15:77711506 NA 0.42 4.79 0.4 4.68e-6 Type 2 diabetes; TGCT cis rs116095464 0.558 rs7703803 chr5:292311 A/G cg22857025 chr5:266934 NA -0.34 -6.64 -0.51 8.6e-10 Breast cancer; TGCT cis rs9467773 0.587 rs10946813 chr6:26345141 A/G cg05738196 chr6:26577821 NA 0.62 6.59 0.51 1.12e-9 Intelligence (multi-trait analysis); TGCT cis rs8180040 1.000 rs7613282 chr3:47389409 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.63 -0.61 2.53e-14 Colorectal cancer; TGCT trans rs7618501 0.521 rs868891 chr3:49949071 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.79 8.11 0.59 4.13e-13 Intelligence (multi-trait analysis); TGCT cis rs4919694 1.000 rs4917379 chr10:104752831 A/T cg04362960 chr10:104952993 NT5C2 1.07 7.07 0.54 9.73e-11 Arsenic metabolism; TGCT cis rs17108533 0.588 rs12886330 chr14:71301048 G/A cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs9325144 0.752 rs12300353 chr12:39154492 G/C cg26384229 chr12:38710491 ALG10B -0.64 -6.04 -0.48 1.67e-8 Morning vs. evening chronotype; TGCT cis rs3796352 1.000 rs34244302 chr3:53102236 C/G cg07884673 chr3:53033167 SFMBT1 0.59 6.05 0.48 1.6e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9868809 0.772 rs34096717 chr3:48719453 A/C cg00383909 chr3:49044727 WDR6 1.04 5.88 0.47 3.6e-8 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs57920188 0.703 rs10915642 chr1:4089244 T/C cg20703997 chr1:4087676 NA 0.49 6.12 0.48 1.11e-8 Interleukin-17 levels; TGCT cis rs7246657 0.722 rs10402671 chr19:38117086 C/T cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs2458413 0.771 rs7010076 chr8:105342827 C/G cg13045555 chr8:105342365 NA -0.4 -6.46 -0.5 2.11e-9 Paget's disease; TGCT cis rs6121246 0.512 rs45443696 chr20:30311396 A/C cg13852791 chr20:30311386 BCL2L1 0.83 8.0 0.58 7.45e-13 Mean corpuscular hemoglobin; TGCT cis rs769267 0.792 rs4808961 chr19:19577215 C/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.47 -0.37 1.76e-5 Tonsillectomy; TGCT cis rs7824557 0.843 rs2736375 chr8:11115749 C/T cg21775007 chr8:11205619 TDH -0.5 -4.83 -0.4 3.9e-6 Retinal vascular caliber; TGCT cis rs9926296 0.585 rs6500450 chr16:89858024 A/G cg27121462 chr16:89883253 FANCA 0.83 9.3 0.64 6.14e-16 Vitiligo; TGCT cis rs9341808 0.667 rs6938280 chr6:80897782 G/A cg08355045 chr6:80787529 NA 0.3 5.09 0.42 1.27e-6 Sitting height ratio; TGCT cis rs6700896 0.500 rs6700421 chr1:66082135 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs308403 0.600 rs13135445 chr4:123664457 C/T cg10495464 chr4:123653540 BBS12;LOC729338 0.67 6.55 0.51 1.4e-9 Blood protein levels; TGCT cis rs7223966 1.000 rs11658175 chr17:61923838 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs12971120 0.891 rs4891558 chr18:72170359 A/G cg26446133 chr18:72167187 CNDP2 -0.35 -6.06 -0.48 1.51e-8 Refractive error; TGCT cis rs1552244 0.572 rs7645759 chr3:10157368 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.51 0.44 2.02e-7 Alzheimer's disease; TGCT cis rs3784262 0.967 rs35511675 chr15:58266978 T/A cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.7 -0.57 3.78e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs60843830 1.000 rs57542652 chr2:228088 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.77 7.58 0.56 6.95e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs3947 0.906 rs709822 chr8:11702313 C/G cg02840367 chr8:11660030 FDFT1 1.0 8.13 0.59 3.82e-13 Blood protein levels; TGCT cis rs2296887 0.841 rs10883717 chr10:103967590 A/G cg26089160 chr10:104170217 PSD -0.56 -4.97 -0.41 2.18e-6 Parkinson's disease; TGCT cis rs7119 0.717 rs7176307 chr15:77816684 G/C cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs9303401 0.614 rs2240719 chr17:56582477 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.71 6.78 0.52 4.45e-10 Cognitive test performance; TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg16325326 chr1:53192061 ZYG11B 0.65 7.94 0.58 1.05e-12 Monocyte count; TGCT cis rs765787 0.530 rs11639403 chr15:45538350 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs709400 0.603 rs2296486 chr14:104003070 A/G cg26031613 chr14:104095156 KLC1 0.89 9.8 0.66 3.77e-17 Body mass index; TGCT cis rs13082711 0.522 rs820617 chr3:27335510 T/C cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg03806693 chr22:41940476 POLR3H -1.15 -13.24 -0.77 1.73e-25 Vitiligo; TGCT cis rs79349575 0.729 rs62075824 chr17:46986679 A/G cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT cis rs769267 0.965 rs12977937 chr19:19429975 C/G cg03709012 chr19:19516395 GATAD2A 0.67 5.72 0.46 7.56e-8 Tonsillectomy; TGCT cis rs12210905 1.000 rs114337870 chr6:27254937 A/C cg08851530 chr6:28072375 NA 1.29 5.49 0.44 2.19e-7 Hip circumference adjusted for BMI; TGCT cis rs1555895 0.568 rs4097329 chr10:844839 T/C cg02193355 chr10:851439 NA 0.22 4.71 0.39 6.6e-6 Survival in rectal cancer; TGCT cis rs17001868 0.568 rs760700 chr22:40800071 C/T cg07138101 chr22:40742427 ADSL -0.74 -5.71 -0.46 8.01e-8 Mammographic density (dense area); TGCT cis rs8177253 1.000 rs8177253 chr3:133480192 A/G cg20276088 chr3:133502917 NA 0.26 5.39 0.44 3.44e-7 Iron status biomarkers; TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg17178900 chr1:205818956 PM20D1 0.58 7.21 0.54 4.81e-11 Menarche (age at onset); TGCT cis rs35934224 0.783 rs34462686 chr22:19859917 A/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.28 -0.43 5.71e-7 Glaucoma (primary open-angle); TGCT cis rs17376456 0.825 rs17372615 chr5:93124768 C/T cg21475434 chr5:93447410 FAM172A 0.63 4.92 0.4 2.72e-6 Diabetic retinopathy; TGCT cis rs739496 0.579 rs3752631 chr12:112376157 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs6540559 0.673 rs17015309 chr1:210007218 C/T cg22029157 chr1:209979665 IRF6 0.71 5.09 0.42 1.3e-6 Cleft lip with or without cleft palate; TGCT cis rs7193541 0.684 rs4888264 chr16:74681632 T/G cg01733217 chr16:74700730 RFWD3 0.99 13.32 0.77 1.14e-25 Multiple myeloma; TGCT cis rs35160687 0.901 rs12472676 chr2:86510815 T/C cg12542933 chr2:85804724 VAMP8 0.39 4.69 0.39 7.08e-6 Night sleep phenotypes; TGCT cis rs7954584 0.567 rs1169071 chr12:122390084 G/T cg22618164 chr12:122356400 WDR66 0.7 6.91 0.53 2.23e-10 Mean corpuscular volume; TGCT trans rs7613875 0.641 rs2624845 chr3:50062437 C/A cg21659725 chr3:3221576 CRBN -0.67 -7.53 -0.56 9.05e-12 Body mass index; TGCT cis rs68170813 0.559 rs3815148 chr7:106938420 G/T cg02696742 chr7:106810147 HBP1 0.69 5.95 0.47 2.61e-8 Coronary artery disease; TGCT cis rs826838 1.000 rs10875991 chr12:39108886 G/C cg26384229 chr12:38710491 ALG10B 1.06 10.35 0.68 1.82e-18 Heart rate; TGCT cis rs13188771 0.651 rs12523298 chr5:100903067 T/A cg18665594 chr5:101119420 NA 0.44 4.47 0.37 1.74e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs916888 0.697 rs199516 chr17:44856485 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 0.59 5.17 0.42 8.98e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7824557 0.564 rs13268126 chr8:11230574 G/A cg21775007 chr8:11205619 TDH -0.64 -6.2 -0.49 7.66e-9 Retinal vascular caliber; TGCT cis rs4689388 0.926 rs9998519 chr4:6292909 C/T cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs1362404 0.648 rs7193742 chr16:51991794 G/A cg03955530 chr16:52681474 NA 0.31 4.55 0.38 1.24e-5 Gut microbiota (bacterial taxa); TGCT cis rs10540 1.000 rs12801148 chr11:511707 T/G cg03934478 chr11:495069 RNH1 0.32 4.82 0.4 4.16e-6 Body mass index; TGCT cis rs2742417 0.603 rs2742457 chr3:45767487 G/A cg04837898 chr3:45731254 SACM1L -0.66 -7.09 -0.54 9.07e-11 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7666738 0.861 rs10018654 chr4:99002226 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.897 rs12481860 chr21:40537836 T/A cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs4642101 0.640 rs7629354 chr3:12827746 T/G cg05775895 chr3:12838266 CAND2 0.66 7.03 0.53 1.21e-10 QRS complex (12-leadsum); TGCT cis rs9611519 0.894 rs4821998 chr22:41468273 C/G cg03806693 chr22:41940476 POLR3H -0.66 -5.98 -0.47 2.25e-8 Neuroticism; TGCT cis rs17539620 0.624 rs117591255 chr6:154839118 G/A cg20019720 chr6:154832845 CNKSR3 0.57 4.99 0.41 2.02e-6 Lipoprotein (a) levels; TGCT cis rs7654585 0.704 rs10212993 chr4:25937476 T/A cg10409131 chr4:25915609 C4orf52 0.75 6.41 0.5 2.78e-9 Obesity-related traits; TGCT cis rs433598 0.894 rs395501 chr16:20683296 C/T cg16616769 chr16:19727142 IQCK;C16orf88 -0.2 -4.58 -0.38 1.1e-5 Schizophrenia; TGCT cis rs367615 0.704 rs11747622 chr5:108844720 G/A cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7552404 1.000 rs4559448 chr1:76203456 A/G cg22875332 chr1:76189707 ACADM 0.77 9.42 0.65 3.17e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs3820068 0.655 rs11587521 chr1:15839206 T/C cg05660106 chr1:15850417 CASP9 1.15 13.74 0.78 1.14e-26 Systolic blood pressure; TGCT cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs9348729 1 rs9348729 chr6:26664268 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.84 -0.46 4.22e-8 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.962 rs6122347 chr20:61661866 C/T cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs910316 1.000 rs175449 chr14:75590846 A/T cg11812906 chr14:75593930 NEK9 -0.73 -7.13 -0.54 7.35e-11 Height; TGCT cis rs7542091 0.739 rs10863793 chr1:210037420 G/A cg22029157 chr1:209979665 IRF6 0.58 5.57 0.45 1.5e-7 Monobrow; TGCT cis rs10464366 0.571 rs13233049 chr7:39187536 C/T cg18850127 chr7:39170497 POU6F2 0.33 7.18 0.54 5.5e-11 IgG glycosylation; TGCT cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs2762353 0.603 rs12201071 chr6:25778055 C/T cg12310025 chr6:25882481 NA 0.48 4.68 0.39 7.3e-6 Blood metabolite levels; TGCT trans rs7618501 0.602 rs2624816 chr3:50117312 T/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.87 -9.4 -0.65 3.62e-16 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.864 rs60309406 chr17:41435665 C/T cg05368731 chr17:41323189 NBR1 1.19 13.97 0.78 3.22e-27 Menopause (age at onset); TGCT trans rs7613875 0.620 rs17657688 chr3:50033228 C/T cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT cis rs854765 0.583 rs10048206 chr17:17866897 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs739401 0.611 rs3782069 chr11:3033275 G/A cg05729581 chr11:3078854 CARS -0.55 -5.24 -0.43 6.76e-7 Longevity; TGCT cis rs2228479 0.618 rs62052174 chr16:89950901 G/A cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs13108904 0.870 rs13115355 chr4:1261576 G/A cg00684032 chr4:1343700 KIAA1530 0.22 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs9372498 0.536 rs9481808 chr6:118784571 G/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs2439831 0.850 rs28524541 chr15:44124831 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.71 4.44 0.37 1.99e-5 Lung cancer in ever smokers; TGCT cis rs7523273 0.925 rs12132780 chr1:207999605 C/T cg22525895 chr1:207977042 MIR29B2 -0.48 -8.57 -0.61 3.42e-14 Schizophrenia; TGCT cis rs941873 0.805 rs10762860 chr10:81117794 C/G cg09469691 chr10:81107165 PPIF 0.54 5.37 0.43 3.75e-7 Height; TGCT cis rs7226408 0.857 rs17652513 chr18:34483319 C/T cg06757138 chr18:34340585 FHOD3 0.26 5.24 0.43 6.63e-7 Obesity-related traits; TGCT cis rs13177918 0.677 rs2070844 chr5:149823785 G/A cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7618915 0.501 rs13079063 chr3:52744460 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs698813 0.674 rs4952707 chr2:44500683 G/C cg00619915 chr2:44497795 NA -0.22 -4.91 -0.4 2.79e-6 Adverse response to chemotherapy in breast cancer (alopecia) (paclitaxel); TGCT cis rs35146811 0.520 rs1015538 chr7:99626035 A/G cg13334819 chr7:99746414 C7orf59 0.61 5.68 0.45 8.98e-8 Coronary artery disease; TGCT cis rs35160687 0.842 rs10200526 chr2:86527599 G/A cg12542933 chr2:85804724 VAMP8 0.41 4.9 0.4 2.97e-6 Night sleep phenotypes; TGCT cis rs10504229 1.000 rs117231141 chr8:58185465 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs322662 1.000 rs322662 chr3:25356873 A/G cg23683962 chr3:24549503 NA 0.18 4.45 0.37 1.9e-5 Calcium levels; TGCT cis rs651907 0.535 rs11919389 chr3:101424458 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.54 5.0 0.41 1.91e-6 Colorectal cancer; TGCT cis rs6933660 0.512 rs13198669 chr6:151799924 A/G cg03627880 chr6:151815985 C6orf97 0.72 6.84 0.52 3.29e-10 Menarche (age at onset); TGCT cis rs6840360 0.571 rs875668 chr4:152525661 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT trans rs9859260 0.744 rs492288 chr3:195784210 C/T cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs6977660 0.507 rs72591450 chr7:19775480 A/G cg05791153 chr7:19748676 TWISTNB 1.01 6.63 0.51 9.26e-10 Thyroid stimulating hormone; TGCT cis rs2243480 1.000 rs56985706 chr7:65394562 C/T cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs4851254 0.660 rs35869550 chr2:100684578 T/A cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs7264396 0.790 rs2425083 chr20:34300456 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.96e-7 Total cholesterol levels; TGCT cis rs9921338 0.961 rs6498185 chr16:11444726 C/T cg00044050 chr16:11439710 C16orf75 -0.71 -5.47 -0.44 2.43e-7 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs362272 0.505 rs3129310 chr4:3301388 T/G cg22655196 chr4:3374909 RGS12 0.24 4.69 0.39 7.07e-6 Serum sulfate level; TGCT cis rs9322193 0.923 rs62441284 chr6:150072678 C/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs1552244 0.572 rs6785976 chr3:10168647 A/G cg00149659 chr3:10157352 C3orf10 1.13 7.41 0.55 1.72e-11 Alzheimer's disease; TGCT cis rs8031584 0.958 rs11629793 chr15:31238423 G/A cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.29e-6 Huntington's disease progression; TGCT cis rs7208859 0.673 rs9894876 chr17:29182020 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs941408 1.000 rs1736181 chr19:2797703 C/T cg19676328 chr12:49525230 TUBA1B -0.77 -7.68 -0.57 4.09e-12 Total cholesterol levels; TGCT cis rs514406 0.861 rs4926932 chr1:53247495 C/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs6845621 0.901 rs207294 chr4:18918758 C/A cg12196642 chr4:18937545 NA -0.24 -4.45 -0.37 1.91e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs12681287 0.640 rs2953516 chr8:87332545 C/T cg27223183 chr8:87520930 FAM82B -0.94 -7.06 -0.54 1.02e-10 Caudate activity during reward; TGCT cis rs8177253 1.000 rs6439439 chr3:133481498 G/T cg16414030 chr3:133502952 NA -0.61 -9.47 -0.65 2.44e-16 Iron status biomarkers; TGCT cis rs72945132 0.619 rs61887436 chr11:70243337 C/T cg00319359 chr11:70116639 PPFIA1 1.01 7.03 0.53 1.21e-10 Coronary artery disease; TGCT cis rs10206020 0.836 rs10202105 chr2:1553301 C/T cg01028140 chr2:1542097 TPO -0.34 -4.86 -0.4 3.54e-6 IgG glycosylation; TGCT cis rs78487399 0.808 rs13417883 chr2:43700154 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4654899 0.833 rs10127757 chr1:21490045 A/G cg01072550 chr1:21505969 NA -0.48 -7.14 -0.54 7.03e-11 Superior frontal gyrus grey matter volume; TGCT cis rs17725255 0.636 rs1205222 chr20:18131766 T/G cg02706653 chr20:17208584 PCSK2 0.6 4.48 0.37 1.65e-5 Anorexia nervosa; TGCT cis rs904251 0.797 rs1757181 chr6:37485728 A/G cg01843034 chr6:37503916 NA 0.49 6.01 0.47 1.91e-8 Cognitive performance; TGCT cis rs7618915 0.533 rs35107891 chr3:52613656 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs6714788 0.565 rs9308833 chr2:100662618 C/T cg22139774 chr2:100720529 AFF3 -0.41 -6.58 -0.51 1.19e-9 Intelligence (multi-trait analysis); TGCT trans rs877282 0.853 rs7083589 chr10:754494 G/A cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs1129187 0.967 rs3805951 chr6:42937176 C/A cg02353165 chr6:42928485 GNMT 0.94 9.64 0.65 9.69e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9311474 1.000 rs9311474 chr3:52338852 T/C cg07507251 chr3:52567010 NT5DC2 0.46 6.21 0.49 7.16e-9 Electroencephalogram traits; TGCT cis rs9383153 1.000 rs2237223 chr6:16329741 G/A cg20052079 chr6:15504923 JARID2 0.92 5.01 0.41 1.82e-6 Gambling; TGCT cis rs13118159 0.509 rs1882098 chr4:1352431 T/C cg19318889 chr4:1322082 MAEA 0.27 6.66 0.51 7.93e-10 Longevity; TGCT cis rs67460515 0.892 rs1478566 chr3:161030335 A/T cg03342759 chr3:160939853 NMD3 -0.49 -5.31 -0.43 4.98e-7 Parkinson's disease; TGCT cis rs1857353 1.000 rs79777526 chr1:75909485 T/C cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs10927875 0.501 rs61782229 chr1:16220118 G/A cg21385522 chr1:16154831 NA -0.94 -9.41 -0.65 3.36e-16 Dilated cardiomyopathy; TGCT cis rs2562456 0.516 rs56072098 chr19:21651960 G/T cg01304269 chr19:21688519 ZNF429 -0.56 -4.7 -0.39 6.71e-6 Pain; TGCT cis rs910316 1.000 rs12897094 chr14:75579416 C/T cg23033748 chr14:75592666 NEK9 0.28 4.72 0.39 6.22e-6 Height; TGCT cis rs9811920 0.609 rs4244713 chr3:99679584 T/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.62 6.98 0.53 1.6e-10 Axial length; TGCT cis rs2692947 0.702 rs2312955 chr2:96777168 T/G cg22654517 chr2:96458247 NA -0.21 -4.58 -0.38 1.11e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2456568 0.570 rs1827932 chr11:93663319 A/T cg26875233 chr11:93583750 C11orf90 -0.42 -5.04 -0.41 1.59e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3806843 0.576 rs246008 chr5:140338485 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7937682 0.889 rs10789844 chr11:111579109 A/T cg09085632 chr11:111637200 PPP2R1B -1.12 -12.65 -0.75 4.62e-24 Primary sclerosing cholangitis; TGCT cis rs12188164 0.965 rs11744539 chr5:451425 C/T cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs981844 0.743 rs17371461 chr4:154759220 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.89 0.62 5.85e-15 Response to statins (LDL cholesterol change); TGCT cis rs13108904 0.967 rs11247987 chr4:1294532 G/A cg05665937 chr4:1216051 CTBP1 0.25 4.68 0.39 7.33e-6 Obesity-related traits; TGCT cis rs250677 1.000 rs190378 chr5:148434275 G/T cg23229984 chr5:148520753 ABLIM3 0.21 4.96 0.41 2.22e-6 Breast cancer; TGCT cis rs7027203 0.828 rs4744287 chr9:96585567 A/G cg13679303 chr9:96623674 NA 0.66 10.69 0.69 2.63e-19 DNA methylation (variation); TGCT cis rs11098499 0.954 rs6849171 chr4:120409549 G/A cg09307838 chr4:120376055 NA 0.72 7.08 0.54 9.22e-11 Corneal astigmatism; TGCT cis rs9549367 0.789 rs34448227 chr13:113884754 A/C cg00898013 chr13:113819073 PROZ -0.39 -4.79 -0.4 4.67e-6 Platelet distribution width; TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg11965913 chr1:205819406 PM20D1 0.61 9.92 0.67 2e-17 Menarche (age at onset); TGCT cis rs7659604 1.000 rs28532673 chr4:122664323 A/G cg19748678 chr4:122722346 EXOSC9 -0.57 -5.49 -0.44 2.15e-7 Type 2 diabetes; TGCT cis rs2836974 0.644 rs2836986 chr21:40702136 A/C cg11644478 chr21:40555479 PSMG1 -0.53 -4.57 -0.38 1.17e-5 Cognitive function; TGCT cis rs595982 0.527 rs55706579 chr19:49382969 G/A cg17863274 chr19:49399704 TULP2 -0.55 -7.89 -0.58 1.32e-12 Red cell distribution width; TGCT cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg08280861 chr8:58055591 NA 0.39 4.76 0.39 5.35e-6 Developmental language disorder (linguistic errors); TGCT cis rs76935404 0.811 rs12150973 chr19:41434524 T/C cg19493303 chr19:41414353 NA 0.38 4.55 0.38 1.25e-5 nicotine metabolite ratio in current smokers; TGCT trans rs57221529 0.766 rs56278696 chr5:582669 A/G cg11887960 chr12:57824829 NA 1.14 9.3 0.64 6.29e-16 Lung disease severity in cystic fibrosis; TGCT cis rs909685 0.538 rs5757596 chr22:39668961 G/T cg17798944 chr22:39715225 SNORD43;RPL3 0.74 8.41 0.6 8.05e-14 Rheumatoid arthritis; TGCT cis rs13424612 0.864 rs4854071 chr2:240885050 C/T cg26363272 chr2:240904871 NDUFA10 0.29 4.99 0.41 1.96e-6 Odorant perception (isobutyraldehyde); TGCT cis rs4372836 0.729 rs4132617 chr2:29031312 C/A cg09522027 chr2:28974177 PPP1CB -0.69 -7.27 -0.55 3.54e-11 Body mass index; TGCT cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7267979 1.000 rs4815407 chr20:25341478 G/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs796364 0.806 rs1509832 chr2:200874443 G/T cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT cis rs597539 0.652 rs660614 chr11:68659488 G/A cg06112835 chr11:68658793 MRPL21 0.47 8.14 0.59 3.49e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.723 rs35327100 chr4:98977788 C/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs4319547 1.000 rs6489157 chr12:123101673 C/G cg23029597 chr12:123009494 RSRC2 0.29 4.75 0.39 5.43e-6 Body mass index; TGCT cis rs11711311 1.000 rs12631232 chr3:113497386 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.73 -6.63 -0.51 9.38e-10 IgG glycosylation; TGCT cis rs9398235 0.929 rs4945861 chr6:110728429 C/T cg00083206 chr6:110721305 DDO 0.47 4.78 0.39 4.92e-6 Systemic lupus erythematosus; TGCT cis rs4516970 0.826 rs59246098 chr6:160149462 C/CA cg25736982 chr6:160182554 ACAT2 0.7 6.49 0.5 1.88e-9 Iron status biomarkers; TGCT cis rs4689388 0.853 rs1079216 chr4:6282473 T/C cg25554036 chr4:6271136 WFS1 0.57 7.77 0.57 2.63e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7208859 0.623 rs216433 chr17:28921860 T/C cg19761014 chr17:28927070 LRRC37B2 0.56 4.81 0.4 4.32e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.712 rs11731393 chr4:98859070 G/C cg17366294 chr4:99064904 C4orf37 0.7 5.2 0.42 8.14e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9913156 0.793 rs8074545 chr17:4567337 C/G cg19197139 chr17:4613644 ARRB2 -0.87 -8.05 -0.59 5.79e-13 Lymphocyte counts; TGCT cis rs17068510 0.572 rs11777171 chr8:3875443 C/T cg25338036 chr8:3047536 CSMD1 -0.46 -4.88 -0.4 3.19e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.59 -6.01 -0.47 1.92e-8 Intelligence (multi-trait analysis); TGCT cis rs7216064 1.000 rs8081517 chr17:65845697 A/T cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7666738 0.753 rs35146453 chr4:98902278 A/G cg17366294 chr4:99064904 C4orf37 0.67 6.83 0.52 3.3e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7975161 1.000 rs7975161 chr12:104645405 C/T cg25273343 chr12:104657179 TXNRD1 0.32 4.88 0.4 3.2e-6 Toenail selenium levels; TGCT cis rs9534288 0.789 rs4942470 chr13:46636652 A/G cg15192986 chr13:46630673 CPB2 -0.51 -6.19 -0.49 8.15e-9 Blood protein levels; TGCT trans rs916888 0.821 rs199509 chr17:44858728 G/A cg07870213 chr5:140052090 DND1 -0.62 -7.4 -0.55 1.84e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6121246 0.520 rs6060425 chr20:30224355 C/T cg21427119 chr20:30132790 HM13 -0.37 -4.95 -0.41 2.4e-6 Mean corpuscular hemoglobin; TGCT cis rs9952991 0.883 rs2847293 chr18:12782448 A/T cg23598886 chr18:12777645 NA 0.62 5.78 0.46 5.63e-8 Inflammatory skin disease; TGCT cis rs739496 0.579 rs7956495 chr12:112295693 T/G cg10833066 chr12:111807467 FAM109A 0.38 5.4 0.44 3.24e-7 Platelet count; TGCT cis rs910316 1.000 rs3742780 chr14:75505008 G/C cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.32e-6 Height; TGCT cis rs7089973 0.872 rs41284358 chr10:116622339 A/G cg03647239 chr10:116582469 FAM160B1 0.52 4.62 0.38 9.32e-6 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7937682 0.889 rs567859 chr11:111486738 A/G cg09085632 chr11:111637200 PPP2R1B -1.05 -11.36 -0.71 6.21e-21 Primary sclerosing cholangitis; TGCT cis rs13191362 1.000 rs67646369 chr6:163003233 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7119038 0.818 rs2155433 chr11:118612921 G/A cg19308663 chr11:118741387 NA 0.24 4.79 0.4 4.65e-6 Sjögren's syndrome; TGCT cis rs28785552 0.931 rs10406850 chr19:53240807 A/C cg04754360 chr19:53238445 ZNF611 -0.63 -5.05 -0.41 1.57e-6 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs6809651 0.524 rs4686730 chr3:185805993 C/T cg00760338 chr3:185826511 ETV5 -0.77 -6.32 -0.49 4.23e-9 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs801193 1.000 rs6975195 chr7:66124774 T/A cg00343986 chr7:65444356 GUSB -0.23 -5.13 -0.42 1.07e-6 Aortic root size; TGCT cis rs11190604 0.767 rs872290 chr10:102198879 G/A cg23241863 chr10:102295624 HIF1AN 0.64 4.8 0.4 4.42e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.791 rs62318907 chr4:99037120 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10262624 0.528 rs722294 chr7:23746585 A/C cg09690326 chr7:23720549 C7orf46 0.43 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs7714584 1.000 rs1896707 chr5:150245129 C/T cg22134413 chr5:150180641 NA 0.8 6.27 0.49 5.47e-9 Crohn's disease; TGCT cis rs4148883 0.689 rs2602861 chr4:100030896 C/T cg12011299 chr4:100065546 ADH4 0.38 5.74 0.46 6.75e-8 Alcohol dependence; TGCT cis rs763014 0.931 rs1981483 chr16:630665 G/A cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs7829975 0.557 rs7816427 chr8:8545884 T/C cg06636001 chr8:8085503 FLJ10661 -0.6 -5.18 -0.42 8.83e-7 Mood instability; TGCT cis rs2180341 0.538 rs11556354 chr6:127664661 G/A cg24812749 chr6:127587940 RNF146 0.62 5.41 0.44 3.13e-7 Breast cancer; TGCT cis rs4664308 0.935 rs4292050 chr2:160940899 G/T cg03641300 chr2:160917029 PLA2R1 -0.27 -6.58 -0.51 1.2e-9 Idiopathic membranous nephropathy; TGCT cis rs1670533 1.000 rs2290410 chr4:1052078 A/T cg20887711 chr4:1340912 KIAA1530 0.7 5.33 0.43 4.53e-7 Recombination rate (females); TGCT cis rs933688 1.000 rs889213 chr5:90682151 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.42 0.6 7.91e-14 Smoking behavior; TGCT cis rs114540395 0.925 rs77449307 chr10:103385599 A/C cg03300883 chr10:102748874 C10orf2 0.42 4.58 0.38 1.13e-5 Schizophrenia; TGCT trans rs12339966 0.653 rs4740488 chr9:11277303 C/G cg07173112 chr1:1114698 TTLL10 -0.33 -6.69 -0.51 6.89e-10 Systolic blood pressure; TGCT cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs2204008 0.774 rs11520273 chr12:38354075 A/T cg26384229 chr12:38710491 ALG10B 0.79 6.98 0.53 1.61e-10 Bladder cancer; TGCT cis rs7843479 0.870 rs1809498 chr8:21836384 C/G cg17168535 chr8:21777572 XPO7 -0.61 -5.52 -0.44 1.94e-7 Mean corpuscular volume; TGCT cis rs7829975 0.514 rs2920991 chr8:8259117 T/A cg15556689 chr8:8085844 FLJ10661 0.73 6.64 0.51 8.65e-10 Mood instability; TGCT cis rs1008375 0.966 rs3796812 chr4:17582051 G/A cg18681998 chr4:17616180 MED28 0.88 9.22 0.64 9.770000000000001e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1403694 1.000 rs2689197 chr3:186438346 C/T cg12454167 chr3:186435060 KNG1 0.42 7.37 0.55 2.15e-11 Blood protein levels; TGCT cis rs12971120 0.947 rs8083001 chr18:72165058 A/G cg25817165 chr18:72167213 CNDP2 -0.29 -5.42 -0.44 3.02e-7 Refractive error; TGCT cis rs1205863 1.000 rs1205861 chr6:11943295 T/G cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs9830388 0.528 rs7645209 chr3:23482138 A/T cg25382821 chr3:23496403 UBE2E2 -0.26 -4.62 -0.38 9.44e-6 RR interval (tricyclic/tetracyclic antidepressant use interaction); TGCT cis rs501916 1.000 rs501916 chr15:48053229 C/A cg16110827 chr15:48056943 SEMA6D -0.17 -5.15 -0.42 9.79e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs6121246 0.529 rs6060174 chr20:30183538 G/A cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg03517284 chr6:25882590 NA -0.62 -6.45 -0.5 2.23e-9 Blood metabolite levels; TGCT cis rs6951245 0.554 rs75075857 chr7:1140298 C/T cg23708337 chr7:1209742 NA 0.42 4.84 0.4 3.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg05738196 chr6:26577821 NA 0.87 10.75 0.69 1.87e-19 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.576 rs246002 chr5:140341104 A/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs2760061 0.626 rs635563 chr1:228136834 C/T cg18477163 chr1:228402036 OBSCN -0.32 -6.42 -0.5 2.58e-9 Diastolic blood pressure; TGCT cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg18305652 chr10:134549665 INPP5A 0.33 5.59 0.45 1.37e-7 Migraine; TGCT cis rs13191362 0.507 rs2846535 chr6:163034019 T/C cg21926612 chr6:163149169 PACRG;PARK2 -0.61 -5.85 -0.46 4.17e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10465746 0.967 rs12118434 chr1:84328629 C/T cg10977910 chr1:84465055 TTLL7 0.6 6.07 0.48 1.47e-8 Obesity-related traits; TGCT cis rs807669 0.548 rs9605957 chr22:19187375 G/A cg02655711 chr22:19163373 SLC25A1 0.29 5.69 0.46 8.54e-8 Metabolite levels; TGCT cis rs881375 0.934 rs1468671 chr9:123657502 C/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.38 4.52 0.38 1.43e-5 Rheumatoid arthritis; TGCT cis rs2235642 0.893 rs2076445 chr16:1592266 A/T cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.49 -0.44 2.2e-7 Coronary artery disease; TGCT cis rs11779988 0.545 rs208058 chr8:17820433 G/A cg01800426 chr8:17659068 MTUS1 -0.65 -4.9 -0.4 2.91e-6 Breast cancer; TGCT cis rs35000415 0.873 rs13246321 chr7:128701331 T/C cg06242719 chr7:129414860 MIR183;MIR96 -0.34 -4.67 -0.39 7.58e-6 Systemic lupus erythematosus; TGCT cis rs514406 0.861 rs11206026 chr1:53281708 G/A cg22166914 chr1:53195759 ZYG11B 0.41 7.27 0.55 3.5e-11 Monocyte count; TGCT cis rs6582630 0.502 rs11514371 chr12:38306306 G/C cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.3e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs1580019 0.563 rs2392071 chr7:32572536 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.16 14.73 0.8 5.31e-29 Cognitive ability; TGCT cis rs2197308 0.765 rs2387436 chr12:37935337 C/T cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.22 -0.42 7.16e-7 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs114575045 chr4:119739794 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs892864 0.685 rs6873360 chr5:127734030 T/C cg01939274 chr5:127874478 FBN2 0.91 4.52 0.38 1.44e-5 Multiple system atrophy; TGCT cis rs7267979 0.903 rs6107015 chr20:25216764 G/A cg14121845 chr20:25566513 NINL 0.5 5.51 0.44 1.98e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6840360 0.681 rs4519779 chr4:152301185 G/A cg17479576 chr4:152424074 FAM160A1 -0.56 -6.11 -0.48 1.21e-8 Intelligence (multi-trait analysis); TGCT cis rs9381040 0.610 rs9357345 chr6:41025118 G/C cg03526776 chr6:41159608 TREML2 0.27 5.29 0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs6582630 0.519 rs4294627 chr12:38293982 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.3e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs4788570 0.625 rs2247603 chr16:71609364 G/A cg06353428 chr16:71660113 MARVELD3 -1.45 -12.16 -0.74 6.98e-23 Intelligence (multi-trait analysis); TGCT cis rs9457247 1.000 rs439237 chr6:167391392 A/G cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs9399135 0.622 rs3817776 chr6:135256756 C/T cg22676075 chr6:135203613 NA -0.48 -4.99 -0.41 2.03e-6 Red blood cell count; TGCT cis rs2458413 0.563 rs2458419 chr8:105337141 G/C cg13045555 chr8:105342365 NA -0.39 -6.6 -0.51 1.05e-9 Paget's disease; TGCT trans rs66573146 0.808 rs56268690 chr4:6923887 C/T cg07817883 chr1:32538562 TMEM39B 1.31 7.04 0.53 1.19e-10 Granulocyte percentage of myeloid white cells; TGCT trans rs1814175 0.626 rs1722008 chr11:49897676 A/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.12 -0.54 7.87e-11 Height; TGCT cis rs524023 0.958 rs12802649 chr11:64359627 C/T cg07733098 chr11:64478343 NRXN2 0.31 4.64 0.38 8.82e-6 Urate levels in obese individuals; TGCT cis rs933688 1.000 rs332531 chr5:90790451 G/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.89 7.88 0.58 1.46e-12 Smoking behavior; TGCT cis rs1008375 0.932 rs6814465 chr4:17659034 C/T cg18681998 chr4:17616180 MED28 0.98 10.79 0.7 1.49e-19 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9467711 0.606 rs9358937 chr6:26374274 C/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9383153 1.000 rs7749925 chr6:16340776 C/G cg06493612 chr6:15502050 JARID2 -0.65 -5.46 -0.44 2.47e-7 Gambling; TGCT cis rs7937682 0.883 rs1789358 chr11:111474116 G/A cg09085632 chr11:111637200 PPP2R1B -1.07 -11.45 -0.72 3.83e-21 Primary sclerosing cholangitis; TGCT cis rs1372520 0.873 rs2737026 chr4:90779823 A/G cg15133208 chr4:90757351 SNCA -0.53 -6.26 -0.49 5.76e-9 Neuroticism; TGCT cis rs6964587 1.000 rs11981461 chr7:91692662 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs7824557 0.650 rs2572406 chr8:11092252 C/G cg21775007 chr8:11205619 TDH 0.47 4.44 0.37 1.94e-5 Retinal vascular caliber; TGCT cis rs4523957 0.584 rs7219557 chr17:2086200 G/A cg16513277 chr17:2031491 SMG6 -0.22 -4.96 -0.41 2.28e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9549367 0.865 rs9549366 chr13:113907644 G/A cg18105134 chr13:113819100 PROZ -0.35 -5.94 -0.47 2.68e-8 Platelet distribution width; TGCT cis rs968451 0.906 rs12628367 chr22:39717104 A/C cg17798944 chr22:39715225 SNORD43;RPL3 0.84 8.54 0.61 4.02e-14 Primary biliary cholangitis; TGCT cis rs7659604 0.539 rs7686200 chr4:122764553 C/T cg20573242 chr4:122745356 CCNA2 0.64 5.62 0.45 1.22e-7 Type 2 diabetes; TGCT cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.7 0.46 8.33e-8 Height; TGCT cis rs7552404 1.000 rs6672180 chr1:76123973 C/G cg03433033 chr1:76189801 ACADM 0.85 10.21 0.68 3.81e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6770219 0.516 rs11925189 chr3:186138413 T/A cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs911555 0.755 rs8014013 chr14:103937372 A/G cg23461800 chr14:103021989 NA -0.35 -4.61 -0.38 9.72e-6 Intelligence (multi-trait analysis); TGCT cis rs3785574 1.000 rs7223257 chr17:61787684 T/C cg11494091 chr17:61959527 GH2 0.42 7.39 0.55 1.86e-11 Height; TGCT cis rs8031584 0.918 rs35784593 chr15:31254588 G/A cg08704250 chr15:31115839 NA -0.35 -4.94 -0.41 2.47e-6 Huntington's disease progression; TGCT cis rs7617773 0.817 rs9311421 chr3:48293078 G/A cg11946769 chr3:48343235 NME6 0.76 6.66 0.51 7.89e-10 Coronary artery disease; TGCT cis rs1878931 0.501 rs42329 chr16:3425524 G/A cg05754148 chr16:3507555 NAT15 0.33 4.67 0.39 7.61e-6 Body mass index (adult); TGCT cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Vitiligo; TGCT cis rs7829975 0.501 rs4840353 chr8:8580570 A/G cg17143192 chr8:8559678 CLDN23 -0.48 -4.81 -0.4 4.29e-6 Mood instability; TGCT cis rs10504229 0.861 rs60346509 chr8:58196050 G/T cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs877282 0.853 rs12777155 chr10:754731 G/C cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs7267979 1.000 rs6115182 chr20:25410259 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs793571 0.502 rs421829 chr15:59079902 G/C cg05156742 chr15:59063176 FAM63B 0.56 5.26 0.43 6.22e-7 Schizophrenia; TGCT cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg13395646 chr4:1353034 KIAA1530 -0.35 -4.58 -0.38 1.11e-5 Obesity-related traits; TGCT cis rs2980439 0.783 rs2955587 chr8:8098079 A/G cg15462221 chr8:8086144 FLJ10661 -0.57 -5.29 -0.43 5.23e-7 Neuroticism; TGCT cis rs11190604 0.697 rs12355942 chr10:102201320 T/C cg16342193 chr10:102329863 NA 0.39 5.16 0.42 9.7e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.830 rs13139024 chr4:99020700 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.798 rs6705583 chr2:99602625 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.86 -8.66 -0.61 2.13e-14 Chronic sinus infection; TGCT cis rs2115536 1.000 rs2115540 chr15:80190308 A/G cg00225070 chr15:80189496 MTHFS 0.61 5.53 0.44 1.82e-7 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9911578 1.000 rs7207693 chr17:57016525 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs826838 1.000 rs7315028 chr12:38710523 G/A cg13010199 chr12:38710504 ALG10B 0.82 6.8 0.52 3.99e-10 Heart rate; TGCT cis rs798766 1.000 rs798756 chr4:1707447 T/C cg05874882 chr4:1763078 NA -0.38 -5.2 -0.42 7.93e-7 Bladder cancer;Urinary bladder cancer; TGCT cis rs5769707 0.605 rs9616702 chr22:50025938 A/G cg05373962 chr22:49881684 NA -0.31 -5.24 -0.43 6.74e-7 Monocyte count;Monocyte percentage of white cells; TGCT trans rs524675 0.581 rs79446337 chr4:13956492 G/A cg02315626 chr17:27188560 MIR451;MIR144 0.42 6.87 0.53 2.82e-10 Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals; TGCT cis rs6540559 0.546 rs75308488 chr1:210030639 T/C cg22029157 chr1:209979665 IRF6 0.78 5.69 0.46 8.55e-8 Cleft lip with or without cleft palate; TGCT cis rs9811920 0.809 rs793443 chr3:99573547 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.43 4.89 0.4 3.05e-6 Axial length; TGCT cis rs611744 0.647 rs2848620 chr8:109249551 G/T cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs10782582 0.593 rs74968421 chr1:76233496 T/C cg22875332 chr1:76189707 ACADM -0.45 -4.98 -0.41 2.06e-6 Daytime sleep phenotypes; TGCT cis rs11671005 0.779 rs55875034 chr19:58983558 T/G cg07764513 chr19:58919909 ZNF584 -0.71 -4.59 -0.38 1.06e-5 Mean platelet volume; TGCT cis rs8031584 0.706 rs2177670 chr15:31157751 G/T cg08109568 chr15:31115862 NA -0.38 -5.03 -0.41 1.67e-6 Huntington's disease progression; TGCT cis rs642803 1.000 rs642803 chr11:65560620 C/T cg27068330 chr11:65405492 SIPA1 0.56 4.97 0.41 2.19e-6 Urate levels; TGCT cis rs8028182 0.636 rs8029112 chr15:75808972 T/C cg20655648 chr15:75932815 IMP3 0.6 4.65 0.38 8.54e-6 Sudden cardiac arrest; TGCT cis rs4294134 0.608 rs11767012 chr7:135246747 T/C cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs2729354 0.729 rs2848634 chr11:57252328 G/A cg24343310 chr11:57249947 NA 0.28 4.59 0.38 1.05e-5 Blood protein levels; TGCT trans rs1973993 0.691 rs11165623 chr1:96893000 G/A cg10631902 chr5:14652156 NA 0.4 10.7 0.69 2.56e-19 Weight; TGCT cis rs7937682 0.855 rs490897 chr11:111487914 A/G cg09085632 chr11:111637200 PPP2R1B -1.1 -11.94 -0.73 2.41e-22 Primary sclerosing cholangitis; TGCT cis rs954108 0.772 rs1592058 chr13:29369519 C/G cg11788234 chr13:29393811 NA -0.39 -4.72 -0.39 6.26e-6 Obesity-related traits; TGCT cis rs6089829 0.925 rs6062396 chr20:61667949 T/C cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs950776 0.745 rs3743075 chr15:78909452 T/C cg06917634 chr15:78832804 PSMA4 -0.58 -4.64 -0.38 8.84e-6 Sudden cardiac arrest; TGCT cis rs2702888 0.503 rs2702931 chr8:6758979 A/C cg26795848 chr8:6756730 NA -0.31 -6.18 -0.49 8.38e-9 Blood pressure; TGCT cis rs6500602 0.627 rs841231 chr16:4583147 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.4 -7.15 -0.54 6.75e-11 Schizophrenia; TGCT cis rs5769707 0.837 rs5770599 chr22:50019981 C/G cg20744362 chr22:50050164 C22orf34 0.29 4.54 0.38 1.29e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9906944 0.707 rs4794020 chr17:47111399 C/T cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs3772130 0.962 rs11719093 chr3:121487686 G/A cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.74 0.39 5.87e-6 Cognitive performance; TGCT cis rs11785400 1.000 rs7459630 chr8:143738585 A/C cg10596483 chr8:143751796 JRK 0.57 6.12 0.48 1.12e-8 Schizophrenia; TGCT cis rs7819412 0.623 rs7833435 chr8:10801137 A/G cg27411982 chr8:10470053 RP1L1 -0.24 -4.93 -0.4 2.62e-6 Triglycerides; TGCT cis rs3809863 0.602 rs6504833 chr17:45396087 A/G cg08085267 chr17:45401833 C17orf57 -0.67 -7.87 -0.58 1.5e-12 Glaucoma (primary open-angle); TGCT cis rs3849570 1.000 rs4411908 chr3:81802418 A/C cg07356753 chr3:81810745 GBE1 -0.72 -6.23 -0.49 6.58e-9 Waist circumference;Body mass index; TGCT cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.9 7.25 0.55 3.93e-11 Platelet count; TGCT cis rs10751667 0.643 rs7396951 chr11:927355 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs1218582 0.803 rs7531728 chr1:154840516 C/A cg06418219 chr1:154948305 SHC1;CKS1B -0.64 -6.41 -0.5 2.72e-9 Prostate cancer; TGCT cis rs453301 0.682 rs2929451 chr8:9085295 A/T cg15556689 chr8:8085844 FLJ10661 0.7 6.54 0.51 1.47e-9 Joint mobility (Beighton score); TGCT cis rs79057730 0.599 rs9458 chr7:825494 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 -0.65 -6.33 -0.49 4.13e-9 Initial pursuit acceleration; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg09033563 chr22:24373618 LOC391322 -0.48 -4.65 -0.39 8.35e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8031584 0.958 rs35256769 chr15:31237776 G/A cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.29e-6 Huntington's disease progression; TGCT cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg03517284 chr6:25882590 NA 0.52 4.73 0.39 6.01e-6 Intelligence (multi-trait analysis); TGCT cis rs2066819 1.000 rs2695788 chr12:56697110 G/A cg26714650 chr12:56694279 CS 1.51 8.1 0.59 4.38e-13 Psoriasis vulgaris; TGCT cis rs6504663 0.558 rs11871603 chr17:48559037 T/G cg03168497 chr17:48586147 MYCBPAP 0.46 4.9 0.4 2.98e-6 Visceral fat; TGCT cis rs4689592 0.523 rs3857179 chr4:7070496 T/A cg26116260 chr4:7069785 GRPEL1 1.13 11.15 0.71 1.99e-20 Monocyte percentage of white cells; TGCT cis rs7666738 0.893 rs11729640 chr4:99052699 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs2290402 0.536 rs3775127 chr4:886061 G/A cg23332689 chr4:987652 IDUA;SLC26A1 0.33 5.0 0.41 1.94e-6 Type 2 diabetes; TGCT cis rs7914558 1.000 rs10883837 chr10:104896486 G/A cg15744005 chr10:104629667 AS3MT -0.42 -5.24 -0.43 6.69e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs514406 0.679 rs960570 chr1:53237763 A/G cg27535305 chr1:53392650 SCP2 0.26 5.13 0.42 1.09e-6 Monocyte count; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg26516362 chr5:178986906 RUFY1 -0.43 -4.76 -0.39 5.21e-6 Lung cancer; TGCT cis rs790110 1.000 rs790130 chr3:122384661 C/G cg07366462 chr3:123162899 ADCY5 0.42 4.71 0.39 6.54e-6 Acoustic startle blink response; TGCT cis rs10193935 0.901 rs13429697 chr2:42529818 C/T cg27598129 chr2:42591480 NA -0.41 -5.65 -0.45 1.04e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7226408 0.857 rs3747896 chr18:34647323 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs612683 0.735 rs10493923 chr1:100930254 A/G cg06223162 chr1:101003688 GPR88 -0.31 -4.89 -0.4 3.09e-6 Breast cancer; TGCT cis rs2354432 0.607 rs7545467 chr1:146746248 A/G cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs9527 0.590 rs7074395 chr10:104844928 A/C cg15744005 chr10:104629667 AS3MT 0.4 4.63 0.38 9.04e-6 Arsenic metabolism; TGCT cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7662987 0.517 rs1377689 chr4:100021787 A/G cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs7772486 0.641 rs2748489 chr6:146331287 T/G cg23711669 chr6:146136114 FBXO30 0.68 6.39 0.5 3e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4822044 0.561 rs132781 chr22:42046122 T/G cg13695892 chr22:41940480 POLR3H 0.86 7.84 0.58 1.77e-12 Cannabis dependence symptom count; TGCT cis rs9527 0.830 rs3740392 chr10:104636855 T/C cg15744005 chr10:104629667 AS3MT -0.49 -5.59 -0.45 1.38e-7 Arsenic metabolism; TGCT cis rs7010267 0.773 rs13439134 chr8:119918868 G/C cg17171407 chr8:119960777 TNFRSF11B -0.28 -4.97 -0.41 2.2e-6 Total body bone mineral density (age 45-60); TGCT cis rs2050392 0.965 rs2265368 chr10:30690289 G/C cg18806716 chr10:30721971 MAP3K8 -0.44 -5.17 -0.42 9.28e-7 Inflammatory bowel disease; TGCT cis rs7909074 1.000 rs7079573 chr10:45400406 G/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.31 -0.43 4.88e-7 Mean corpuscular volume; TGCT cis rs9549367 0.789 rs7338235 chr13:113888687 T/C cg18105134 chr13:113819100 PROZ -0.33 -5.37 -0.43 3.79e-7 Platelet distribution width; TGCT cis rs9467711 0.745 rs9467714 chr6:26340785 C/T cg02458000 chr6:26745757 NA -0.96 -4.76 -0.39 5.19e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs739496 0.615 rs7136874 chr12:112113658 C/T cg10833066 chr12:111807467 FAM109A 0.35 5.18 0.42 8.89e-7 Platelet count; TGCT cis rs7666738 0.515 rs10015315 chr4:98700137 A/G cg05340658 chr4:99064831 C4orf37 0.5 5.57 0.45 1.5e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11098499 0.954 rs66506550 chr4:120371445 T/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs986417 0.892 rs8017336 chr14:60798682 G/A cg27398547 chr14:60952738 C14orf39 -1.55 -6.83 -0.52 3.44e-10 Gut microbiota (bacterial taxa); TGCT cis rs12142240 0.698 rs17361819 chr1:46828109 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7258465 1.000 rs10164323 chr19:18569492 C/T cg06462663 chr19:18546047 ISYNA1 0.2 4.63 0.38 9.01e-6 Breast cancer; TGCT trans rs7618501 0.538 rs9856572 chr3:50109073 A/T cg21659725 chr3:3221576 CRBN -0.73 -8.48 -0.61 5.64e-14 Intelligence (multi-trait analysis); TGCT trans rs17685 0.753 rs10251863 chr7:75790192 T/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.88 0.62 6.28e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6754311 0.597 rs6760329 chr2:136544752 A/G cg07169764 chr2:136633963 MCM6 -0.71 -6.47 -0.5 2.09e-9 Mosquito bite size; TGCT cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg18305652 chr10:134549665 INPP5A -0.31 -5.66 -0.45 9.81e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs769267 0.899 rs67720221 chr19:19440864 C/T cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.51 -0.38 1.5e-5 Tonsillectomy; TGCT cis rs7809950 0.678 rs7803151 chr7:106934246 G/A cg23024343 chr7:107201750 COG5 -0.43 -5.88 -0.47 3.51e-8 Coronary artery disease; TGCT cis rs17221829 0.733 rs12363392 chr11:89370598 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT trans rs6089829 0.926 rs1060491 chr20:61665817 C/A cg23505145 chr19:12996616 KLF1 -0.79 -8.13 -0.59 3.84e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs10751667 0.666 rs7950967 chr11:955638 G/A cg06064525 chr11:970664 AP2A2 -0.35 -8.22 -0.59 2.29e-13 Alzheimer's disease (late onset); TGCT cis rs1008375 0.932 rs2302394 chr4:17641188 A/G cg10189774 chr4:17578691 LAP3 0.53 4.6 0.38 1.04e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs611744 0.647 rs1448150 chr8:109276161 T/C cg21045802 chr8:109455806 TTC35 0.72 7.39 0.55 1.94e-11 Dupuytren's disease; TGCT cis rs10484885 0.878 rs72921916 chr6:90555990 C/T cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs939658 0.805 rs8035606 chr15:79420245 C/T cg17916960 chr15:79447300 NA -0.5 -7.7 -0.57 3.74e-12 Refractive error; TGCT cis rs2777491 0.874 rs7161772 chr15:41611066 A/T cg18705301 chr15:41695430 NDUFAF1 -0.76 -10.72 -0.69 2.3e-19 Ulcerative colitis; TGCT cis rs2050392 0.767 rs10763786 chr10:30693567 G/C cg13289132 chr10:30722225 MAP3K8 0.42 5.12 0.42 1.12e-6 Inflammatory bowel disease; TGCT cis rs11252926 0.574 rs4881254 chr10:453567 C/T cg18196295 chr10:418757 DIP2C 0.29 4.73 0.39 5.91e-6 Psychosis in Alzheimer's disease; TGCT cis rs10489202 0.608 rs4657733 chr1:168086434 G/A cg24449463 chr1:168025552 DCAF6 -0.54 -5.39 -0.44 3.37e-7 Schizophrenia; TGCT cis rs7726839 0.507 rs60068988 chr5:597668 T/C cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg00786635 chr1:25594202 NA 0.6 6.25 0.49 6.14e-9 Erythrocyte sedimentation rate; TGCT cis rs6840360 0.615 rs12647616 chr4:152607662 G/A cg17479576 chr4:152424074 FAM160A1 -0.6 -6.13 -0.48 1.07e-8 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.626 rs2329021 chr3:49679072 G/A cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs4073582 0.595 rs801739 chr11:65922589 A/G cg16950941 chr11:66035639 RAB1B 0.55 5.27 0.43 5.9e-7 Gout; TGCT cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg18654377 chr3:49208889 KLHDC8B 0.37 4.91 0.4 2.78e-6 Menarche (age at onset); TGCT cis rs17401966 0.838 rs1013952 chr1:10319247 G/A cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs2404602 0.716 rs2164101 chr15:76749117 A/G cg22467129 chr15:76604101 ETFA -0.57 -6.83 -0.52 3.31e-10 Blood metabolite levels; TGCT cis rs9660180 0.836 rs12038134 chr1:1703865 T/A cg13866156 chr1:1669148 SLC35E2 -0.24 -5.86 -0.47 4e-8 Body mass index; TGCT cis rs7674212 0.539 rs6821617 chr4:104128410 G/A cg16532752 chr4:104119610 CENPE -0.6 -5.46 -0.44 2.51e-7 Type 2 diabetes; TGCT cis rs2180341 0.781 rs7742161 chr6:127571676 T/C cg24812749 chr6:127587940 RNF146 0.79 6.6 0.51 1.09e-9 Breast cancer; TGCT cis rs28595532 0.920 rs115878132 chr4:119756239 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs928736 0.557 rs2834083 chr21:34436973 A/G cg04836472 chr21:34405997 NA 0.46 5.62 0.45 1.19e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs4304924 0.500 rs7339081 chr13:79235501 A/G cg07926092 chr13:79233506 RNF219 0.71 5.42 0.44 3.05e-7 Large artery stroke; TGCT cis rs8014204 0.935 rs10141438 chr14:75354600 A/G cg06637938 chr14:75390232 RPS6KL1 -0.75 -7.25 -0.55 4e-11 Caffeine consumption; TGCT cis rs72627509 0.951 rs6554401 chr4:57825336 C/G cg26694713 chr4:57773883 REST 0.73 6.46 0.5 2.17e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2046867 0.908 rs62251600 chr3:72778545 C/T cg25664220 chr3:72788482 NA -0.56 -7.02 -0.53 1.28e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs752590 1.000 rs752590 chr2:113972945 A/G cg27425262 chr2:113953981 PSD4;LOC440839 0.4 4.52 0.38 1.43e-5 Mucinous ovarian carcinoma; TGCT cis rs727505 0.954 rs1014163 chr7:124443604 G/A cg23710748 chr7:124431027 NA -0.27 -4.71 -0.39 6.53e-6 Lewy body disease; TGCT cis rs6540559 0.611 rs6540563 chr1:210019858 C/G cg21951975 chr1:209979733 IRF6 0.64 4.82 0.4 4.12e-6 Cleft lip with or without cleft palate; TGCT cis rs35000415 0.688 rs59110799 chr7:128716007 G/T cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.56 -0.38 1.19e-5 Systemic lupus erythematosus; TGCT cis rs921968 0.541 rs12987171 chr2:219327030 G/C cg02176678 chr2:219576539 TTLL4 0.47 6.72 0.52 5.75e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs2239547 0.522 rs6792578 chr3:53004604 G/A cg10802521 chr3:52805072 NEK4 -0.59 -5.41 -0.44 3.08e-7 Schizophrenia; TGCT cis rs8072100 0.935 rs78551919 chr17:45626002 A/C cg08085267 chr17:45401833 C17orf57 0.48 5.3 0.43 5.03e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs2463822 0.583 rs72919462 chr11:62035663 G/A cg06239285 chr11:62104954 ASRGL1 -0.91 -5.83 -0.46 4.41e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs12291225 0.639 rs61883858 chr11:14294708 C/T cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs2233152 0.656 rs2287691 chr19:41286163 C/G cg11601297 chr19:41224147 ITPKC;ADCK4 0.53 4.86 0.4 3.46e-6 Kawasaki disease; TGCT cis rs12188164 0.930 rs11743825 chr5:475463 C/T cg17553881 chr5:443987 EXOC3;C5orf55 -0.41 -4.74 -0.39 5.66e-6 Cystic fibrosis severity; TGCT cis rs11249608 0.548 rs7704565 chr5:178473923 G/C cg23951258 chr5:178450506 ZNF879 0.44 4.5 0.37 1.57e-5 Pubertal anthropometrics; TGCT cis rs8070740 0.898 rs4790770 chr17:5324893 A/C cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT cis rs597539 0.652 rs686877 chr11:68637169 G/A cg21862992 chr11:68658383 NA 0.46 6.52 0.51 1.6e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs68170813 0.559 rs76208112 chr7:106964222 C/T cg02696742 chr7:106810147 HBP1 -0.68 -5.52 -0.44 1.9e-7 Coronary artery disease; TGCT cis rs4788570 0.566 rs61171207 chr16:71504798 C/T cg06353428 chr16:71660113 MARVELD3 -1.19 -7.71 -0.57 3.49e-12 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs55944282 chr8:58180821 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7017914 0.967 rs6993170 chr8:71693519 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.1e-6 Bone mineral density; TGCT cis rs4819052 0.851 rs8130285 chr21:46671701 G/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.84 7.5 0.56 1.08e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2456568 1.000 rs2456568 chr11:93691332 A/T cg26875233 chr11:93583750 C11orf90 -0.44 -5.63 -0.45 1.12e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9902453 1.000 rs7222308 chr17:28277041 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 7.0 0.53 1.44e-10 Coffee consumption (cups per day); TGCT cis rs3806843 0.576 rs155360 chr5:140309016 C/T cg07102913 chr5:140593443 PCDHB13 -0.49 -4.88 -0.4 3.24e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs8177253 0.965 rs8177245 chr3:133479230 A/G cg01448562 chr3:133502909 NA -0.33 -6.58 -0.51 1.16e-9 Iron status biomarkers; TGCT cis rs2153535 0.580 rs4960433 chr6:8523697 A/G cg23788917 chr6:8435910 SLC35B3 0.64 5.93 0.47 2.86e-8 Motion sickness; TGCT cis rs7772486 0.686 rs857880 chr6:145971115 T/C cg23711669 chr6:146136114 FBXO30 -0.86 -9.6 -0.65 1.2e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs7552404 1.000 rs11161515 chr1:76212559 C/T cg03433033 chr1:76189801 ACADM 0.81 9.52 0.65 1.84e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7223966 0.961 rs17631783 chr17:61687600 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.56 -4.51 -0.38 1.49e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3820068 0.580 rs12082523 chr1:16005792 A/G cg05660106 chr1:15850417 CASP9 -0.65 -6.31 -0.49 4.39e-9 Systolic blood pressure; TGCT cis rs6912958 0.781 rs4334949 chr6:88290150 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs2836950 0.501 rs2836985 chr21:40701169 A/G cg17971929 chr21:40555470 PSMG1 -0.51 -4.48 -0.37 1.7e-5 Menarche (age at onset); TGCT cis rs7635838 0.565 rs347594 chr3:11249528 C/T cg00170343 chr3:11313890 ATG7 0.59 5.5 0.44 2.05e-7 HDL cholesterol; TGCT cis rs1371867 0.875 rs1788178 chr8:101332518 A/C cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs6121246 0.529 rs58757492 chr20:30181425 G/A cg18721089 chr20:30220636 NA -0.63 -6.86 -0.52 2.95e-10 Mean corpuscular hemoglobin; TGCT cis rs7178424 0.742 rs2414755 chr15:62172429 C/T cg00456672 chr15:62358751 C2CD4A -0.3 -4.7 -0.39 6.79e-6 Height; TGCT cis rs3806843 1.000 rs2879089 chr5:140191893 A/T cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs1371867 0.846 rs1660326 chr8:101290447 G/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.51 -0.38 1.48e-5 Atrioventricular conduction; TGCT cis rs7772486 0.738 rs75288066 chr6:146319386 C/A cg05347473 chr6:146136440 FBXO30 0.55 5.06 0.41 1.5e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs55794721 0.509 rs6699896 chr1:25762902 A/T cg10117171 chr1:25599238 RHD -0.34 -5.5 -0.44 2.05e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs7726839 0.574 rs12517345 chr5:628294 G/A cg09021430 chr5:549028 NA -0.38 -5.11 -0.42 1.21e-6 Obesity-related traits; TGCT cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg03188948 chr7:1209495 NA 0.65 5.5 0.44 2.07e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9325144 0.647 rs1875609 chr12:39018259 C/T cg26384229 chr12:38710491 ALG10B -0.6 -5.76 -0.46 6.3e-8 Morning vs. evening chronotype; TGCT cis rs13108904 0.967 rs4428235 chr4:1278891 C/T cg03303774 chr4:1407052 NA 0.31 4.87 0.4 3.31e-6 Obesity-related traits; TGCT cis rs9486715 1.000 rs9486715 chr6:97059769 A/C cg18709589 chr6:96969512 KIAA0776 -0.83 -7.92 -0.58 1.13e-12 Headache; TGCT cis rs7811142 1.000 rs11769700 chr7:100090049 T/C cg00814883 chr7:100076585 TSC22D4 -0.89 -9.26 -0.64 7.79e-16 Platelet count; TGCT cis rs13217239 0.646 rs6456767 chr6:27070543 C/T cg15659132 chr6:26577336 NA -0.55 -5.37 -0.43 3.7e-7 Schizophrenia; TGCT trans rs1814175 0.754 rs10839453 chr11:49955815 A/T cg03929089 chr4:120376271 NA -0.73 -8.42 -0.6 7.65e-14 Height; TGCT cis rs1008375 0.966 rs7658240 chr4:17588950 A/G cg10189774 chr4:17578691 LAP3 -0.61 -5.29 -0.43 5.43e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6951245 1.000 rs80212261 chr7:1114012 C/T cg18402987 chr7:1209562 NA 0.76 6.39 0.5 3e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs797680 0.856 rs637646 chr1:93716383 A/C cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg11141652 chr22:24348549 GSTTP1 0.33 4.6 0.38 1.05e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9926296 0.533 rs10852623 chr16:89865242 T/C cg21285383 chr16:89894308 SPIRE2 0.46 7.34 0.55 2.41e-11 Vitiligo; TGCT cis rs7226408 0.857 rs72894317 chr18:34706241 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs367615 0.704 rs17161885 chr5:108852642 A/G cg17395555 chr5:108820864 NA 0.31 5.73 0.46 7.24e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs227917 1.000 rs227917 chr7:23646317 C/A cg12601843 chr7:23510954 IGF2BP3 0.59 4.53 0.38 1.38e-5 Common carotid intima-media thickness in HIV negative individuals; TGCT cis rs4819052 0.851 rs2838845 chr21:46670812 A/G cg06618935 chr21:46677482 NA -0.36 -5.2 -0.42 8.1e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3916 1.000 rs2014355 chr12:121175524 A/G cg21892295 chr12:121157589 UNC119B -0.22 -4.44 -0.37 1.95e-5 Urinary metabolites (H-NMR features); TGCT cis rs4076764 1.000 rs12740984 chr1:163422151 A/G cg24596788 chr1:163392923 NA 0.16 4.49 0.37 1.6e-5 Motion sickness; TGCT cis rs875971 1.000 rs1167612 chr7:65567976 C/A cg11764359 chr7:65958608 NA -0.57 -5.02 -0.41 1.76e-6 Aortic root size; TGCT cis rs631288 0.793 rs11239952 chr1:146715204 A/G cg25205988 chr1:146714368 CHD1L 1.26 6.08 0.48 1.35e-8 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs17221829 0.645 rs11018705 chr11:89382700 T/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs2486288 0.656 rs1706770 chr15:45575062 T/C cg14582100 chr15:45693742 SPATA5L1 -0.43 -5.11 -0.42 1.18e-6 Glomerular filtration rate; TGCT cis rs2762353 0.776 rs1165177 chr6:25829659 T/A cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.69e-9 Blood metabolite levels; TGCT cis rs6831352 0.918 rs7670638 chr4:100059807 G/C cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT trans rs208520 0.690 rs10944872 chr6:66708239 T/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs7918232 0.941 rs6482598 chr10:27426375 T/C cg14442939 chr10:27389572 ANKRD26 0.72 5.35 0.43 4.16e-7 Breast cancer; TGCT trans rs34421088 0.560 rs2248315 chr8:11397086 T/A cg15556689 chr8:8085844 FLJ10661 -0.75 -7.08 -0.54 9.46e-11 Neuroticism; TGCT cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg13699009 chr12:122356056 WDR66 0.3 6.53 0.51 1.51e-9 Mean corpuscular volume; TGCT cis rs72945132 0.882 rs17160762 chr11:70134766 A/G cg00319359 chr11:70116639 PPFIA1 -0.99 -6.85 -0.52 3.07e-10 Coronary artery disease; TGCT cis rs2463822 0.669 rs72919480 chr11:62043133 G/A cg06239285 chr11:62104954 ASRGL1 -0.87 -5.04 -0.41 1.6e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs478304 0.934 rs610037 chr11:65546857 A/C cg27068330 chr11:65405492 SIPA1 0.72 7.12 0.54 7.68e-11 Acne (severe); TGCT cis rs739496 0.947 rs1029388 chr12:111926901 A/G cg10833066 chr12:111807467 FAM109A 0.33 5.0 0.41 1.88e-6 Platelet count; TGCT cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg21016266 chr12:122356598 WDR66 -0.47 -6.47 -0.5 2.07e-9 Mean corpuscular volume; TGCT cis rs9393777 0.513 rs7754159 chr6:26620312 G/A cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.48 -4.59 -0.38 1.06e-5 Intelligence (multi-trait analysis); TGCT cis rs11997175 0.846 rs6999445 chr8:33732693 G/A ch.8.33884649F chr8:33765107 NA 0.32 4.74 0.39 5.66e-6 Body mass index; TGCT cis rs9467773 1.000 rs3736782 chr6:26505403 C/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.580 rs78894484 chr7:1138721 T/G cg09177884 chr7:1199841 ZFAND2A -0.72 -5.71 -0.46 7.86e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2594989 0.895 rs2594980 chr3:11381387 C/T cg00170343 chr3:11313890 ATG7 0.66 5.26 0.43 6.16e-7 Circulating chemerin levels; TGCT cis rs694739 1.000 rs11231757 chr11:64106317 C/T cg02228329 chr11:64053129 BAD;GPR137 0.78 7.75 0.57 2.92e-12 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs6964587 0.967 rs2282969 chr7:91583772 T/C cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs17767294 0.708 rs72847379 chr6:27873090 G/A cg08851530 chr6:28072375 NA 1.57 7.27 0.55 3.59e-11 Parkinson's disease; TGCT cis rs4638749 0.588 rs13401731 chr2:108885340 C/T cg25838818 chr2:108905173 SULT1C2 -0.33 -5.0 -0.41 1.93e-6 Blood pressure; TGCT cis rs2242116 0.932 rs1531137 chr3:46943028 T/C cg02527881 chr3:46936655 PTH1R -0.3 -5.77 -0.46 5.91e-8 Birth weight; TGCT cis rs1163251 0.756 rs539799 chr1:120208472 C/T cg19096424 chr1:120255104 PHGDH 0.62 6.19 0.49 8.01e-9 Blood metabolite levels; TGCT cis rs2456568 0.802 rs1395386 chr11:93639331 A/G cg14065697 chr11:93583672 C11orf90 0.38 4.81 0.4 4.33e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7829975 0.714 rs4840362 chr8:8670082 C/G cg15556689 chr8:8085844 FLJ10661 -0.67 -6.08 -0.48 1.36e-8 Mood instability; TGCT cis rs11578508 0.508 rs1204677 chr1:208050972 A/G cg22525895 chr1:207977042 MIR29B2 0.33 5.16 0.42 9.39e-7 Heart rate; TGCT cis rs2180341 0.961 rs9375501 chr6:127652539 C/T cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs10114408 0.921 rs1320545 chr9:96655555 A/G cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 7e-6 Colorectal cancer (SNP x SNP interaction); TGCT trans rs877282 0.945 rs12782447 chr10:771870 C/T cg22713356 chr15:30763199 NA 1.11 9.55 0.65 1.55e-16 Uric acid levels; TGCT cis rs7772486 0.632 rs9386128 chr6:146049053 G/A cg23711669 chr6:146136114 FBXO30 -0.88 -9.78 -0.66 4.22e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs17001868 0.568 rs17001846 chr22:40744053 A/G cg07138101 chr22:40742427 ADSL 0.73 5.5 0.44 2.12e-7 Mammographic density (dense area); TGCT cis rs6424115 0.965 rs2502986 chr1:24135292 G/T cg15997130 chr1:24165203 NA 0.91 10.39 0.68 1.4e-18 Immature fraction of reticulocytes; TGCT cis rs10779751 0.690 rs2791659 chr1:11126569 C/A cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs2933343 0.533 rs11915889 chr3:128700866 A/C cg11901034 chr3:128598214 ACAD9 -0.57 -5.29 -0.43 5.34e-7 IgG glycosylation; TGCT trans rs8073060 0.586 rs6505486 chr17:33996776 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6582630 0.502 rs11520276 chr12:38359216 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.52 0.38 1.41e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs4975709 0.589 rs4975707 chr5:1864028 C/T cg15595755 chr5:1867978 NA 0.47 5.47 0.44 2.39e-7 Cardiovascular disease risk factors; TGCT cis rs9952991 0.527 rs2847259 chr18:12775821 A/C cg23544223 chr18:12777786 NA 0.41 4.64 0.38 8.89e-6 Inflammatory skin disease; TGCT cis rs7246657 0.722 rs3101746 chr19:38146400 T/A cg18154014 chr19:37997991 ZNF793 -0.67 -4.69 -0.39 6.96e-6 Coronary artery calcification; TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs875971 0.862 rs6460307 chr7:66060871 A/G cg11764359 chr7:65958608 NA 0.48 4.51 0.38 1.5e-5 Aortic root size; TGCT trans rs17685 0.725 rs7795291 chr7:75725206 C/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.3 0.6 1.51e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs1552244 0.572 rs3894323 chr3:10168967 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs78366141 0.649 rs7666372 chr4:89687531 C/T cg01026744 chr4:89619053 NAP1L5;HERC3 1.26 5.58 0.45 1.43e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs10791323 0.569 rs1119852 chr11:133743022 C/A cg03690763 chr11:133734501 NA -0.3 -5.16 -0.42 9.36e-7 Childhood ear infection; TGCT cis rs12497850 0.931 rs10780033 chr3:48891275 T/C cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs682748 1.000 rs617089 chr5:17146347 C/T cg23987134 chr5:17158319 LOC285696 -0.23 -5.33 -0.43 4.46e-7 Hippocampal atrophy; TGCT cis rs10504229 0.683 rs11774585 chr8:58132685 G/A cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs77948430 0.655 rs77793842 chr8:13157188 A/C cg25598624 chr8:12235727 FAM66A 0.31 4.59 0.38 1.08e-5 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs2455826 0.500 rs2455852 chr3:15688688 C/T cg16303742 chr3:15540471 COLQ -0.23 -4.54 -0.38 1.33e-5 Inflammatory skin disease; TGCT cis rs9894429 0.716 rs7405578 chr17:79588306 C/A cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.98e-6 Eye color traits; TGCT cis rs933688 1.000 rs1964292 chr5:90743608 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.25 0.6 1.91e-13 Smoking behavior; TGCT cis rs12477438 0.798 rs1453562 chr2:99615850 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs8017423 0.647 rs12589952 chr14:90821364 T/C cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs28595532 0.920 rs114963870 chr4:119758099 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2836974 0.897 rs34394827 chr21:40528087 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs12762955 0.507 rs7070724 chr10:1040138 C/T cg20503657 chr10:835505 NA -0.44 -5.62 -0.45 1.17e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs2013441 1.000 rs2703818 chr17:20119976 T/A cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs3540 0.553 rs12592611 chr15:91004093 C/T cg22089800 chr15:90895588 ZNF774 0.76 7.96 0.58 9.24e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs1577917 0.958 rs3900313 chr6:86537154 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs10782582 0.593 rs6675076 chr1:76118503 A/C cg22875332 chr1:76189707 ACADM -0.54 -6.26 -0.49 5.65e-9 Daytime sleep phenotypes; TGCT cis rs62380364 0.613 rs254781 chr5:88000636 C/T cg22951263 chr5:87985283 NA -0.61 -6.46 -0.5 2.13e-9 Intelligence (multi-trait analysis); TGCT cis rs4851254 0.660 rs10209201 chr2:100672808 C/T cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs12188164 1.000 rs56104584 chr5:437542 T/C cg21144161 chr5:423903 AHRR 0.26 4.94 0.41 2.49e-6 Cystic fibrosis severity; TGCT cis rs2354432 0.556 rs7525622 chr1:146774116 G/A cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs4319547 0.656 rs28730465 chr12:122863864 A/C cg08088222 chr12:122070432 ORAI1 -0.25 -4.49 -0.37 1.58e-5 Body mass index; TGCT cis rs7236492 0.688 rs77069608 chr18:77186319 C/T cg15644404 chr18:77186268 NFATC1 -0.35 -4.67 -0.39 7.83e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs6486730 1.000 rs6486730 chr12:129275027 C/T cg09035930 chr12:129282057 SLC15A4 0.39 5.86 0.47 3.84e-8 Systemic lupus erythematosus; TGCT cis rs10791323 0.569 rs10750542 chr11:133713436 T/C cg03690763 chr11:133734501 NA -0.31 -4.92 -0.4 2.73e-6 Childhood ear infection; TGCT cis rs910316 1.000 rs11159117 chr14:75584867 C/T cg11812906 chr14:75593930 NEK9 0.75 7.54 0.56 8.47e-12 Height; TGCT cis rs6952809 0.532 rs10272548 chr7:2439467 G/A cg23289794 chr7:2394357 EIF3B -0.84 -7.21 -0.54 4.72e-11 Multiple sclerosis; TGCT trans rs6089829 0.925 rs3746748 chr20:61667526 C/T cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs9357506 1.000 rs9381440 chr6:46308778 G/A cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs1865760 0.865 rs1541987 chr6:25950397 A/G cg16482183 chr6:26056742 HIST1H1C -0.52 -4.89 -0.4 3.04e-6 Height; TGCT cis rs35306767 0.903 rs10904577 chr10:922077 A/G cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs2204008 0.902 rs11520218 chr12:38223227 G/A cg13010199 chr12:38710504 ALG10B 0.62 4.87 0.4 3.26e-6 Bladder cancer; TGCT cis rs6951245 1.000 rs28528096 chr7:1070912 G/C cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4372836 0.796 rs7580078 chr2:28997001 G/C cg09522027 chr2:28974177 PPP1CB -0.71 -5.9 -0.47 3.18e-8 Body mass index; TGCT cis rs713587 0.713 rs1982200 chr2:25205427 C/T cg15423357 chr2:25149977 NA -0.58 -5.9 -0.47 3.16e-8 Body mass index in non-asthmatics; TGCT cis rs116095464 0.558 rs1812843 chr5:267658 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs4372836 0.729 rs4638745 chr2:29093803 A/G cg09522027 chr2:28974177 PPP1CB 0.67 6.91 0.53 2.24e-10 Body mass index; TGCT cis rs116095464 0.558 rs10077076 chr5:231940 C/T cg22857025 chr5:266934 NA -0.33 -6.57 -0.51 1.22e-9 Breast cancer; TGCT cis rs617219 0.671 rs1062326 chr5:78617534 A/C cg05890484 chr5:78407552 BHMT -0.37 -4.95 -0.41 2.4e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs11792861 0.591 rs4978763 chr9:111728067 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.64 7.34 0.55 2.4e-11 Menarche (age at onset); TGCT cis rs10461617 0.531 rs2662033 chr5:56213410 T/G cg12311346 chr5:56204834 C5orf35 -0.77 -7.11 -0.54 8.24e-11 Type 2 diabetes; TGCT cis rs713587 0.713 rs1077492 chr2:25286435 C/T cg15423357 chr2:25149977 NA -0.6 -6.12 -0.48 1.15e-8 Body mass index in non-asthmatics; TGCT cis rs6570726 0.846 rs1935616 chr6:145943512 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4730250 0.654 rs12705405 chr7:106792517 C/T cg02696742 chr7:106810147 HBP1 0.72 5.89 0.47 3.44e-8 Osteoarthritis; TGCT cis rs11098499 0.863 rs10004484 chr4:120442428 C/T cg09307838 chr4:120376055 NA 0.71 6.96 0.53 1.71e-10 Corneal astigmatism; TGCT cis rs2580764 0.540 rs10174838 chr2:55241216 A/T cg09592903 chr2:55203963 RTN4 -0.27 -5.92 -0.47 3e-8 Mean platelet volume; TGCT cis rs1023500 0.573 rs133380 chr22:42468910 C/T cg05082376 chr22:42548792 NA -0.23 -5.59 -0.45 1.4e-7 Schizophrenia; TGCT cis rs56804039 0.524 rs6991161 chr8:8405994 C/T cg14215082 chr8:9055850 NA -0.45 -4.65 -0.39 8.38e-6 Cervical cancer; TGCT cis rs11718455 0.960 rs13082990 chr3:44005172 T/C cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs7246657 1.000 rs1529957 chr19:37739801 A/G cg24025825 chr19:37761650 NA -0.25 -4.53 -0.38 1.34e-5 Coronary artery calcification; TGCT cis rs35146811 0.660 rs3779046 chr7:99779243 A/G cg13334819 chr7:99746414 C7orf59 -0.74 -6.31 -0.49 4.4e-9 Coronary artery disease; TGCT cis rs3099143 1.000 rs3110381 chr15:77099665 A/T cg21673338 chr15:77095150 SCAPER -0.52 -4.99 -0.41 2.01e-6 Recalcitrant atopic dermatitis; TGCT cis rs853679 0.527 rs853693 chr6:28282648 C/T cg13525197 chr6:28411240 ZSCAN23 -0.46 -4.66 -0.39 8.1e-6 Depression; TGCT cis rs10883723 0.737 rs11191312 chr10:104278601 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.79 7.79 0.57 2.25e-12 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg10150615 chr22:24372951 LOC391322 -1.0 -12.91 -0.76 1.1e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs4512344 0.509 rs2409784 chr8:11396856 G/T cg15556689 chr8:8085844 FLJ10661 -0.81 -8.5 -0.61 5.1e-14 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1348850 0.958 rs4893941 chr2:178269531 A/T cg22681709 chr2:178499509 PDE11A -0.35 -4.6 -0.38 1.03e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2019872 0.543 rs216175 chr17:2167690 A/C cg24156229 chr17:1948635 NA 0.37 4.55 0.38 1.26e-5 Schizophrenia; TGCT trans rs3780486 0.846 rs4584234 chr9:33147479 G/A cg20290983 chr6:43655470 MRPS18A 1.14 13.92 0.78 4.12e-27 IgG glycosylation; TGCT cis rs6141769 0.542 rs6058833 chr20:31316767 T/G cg13636640 chr20:31349939 DNMT3B -0.52 -4.54 -0.38 1.34e-5 Subjective well-being; TGCT cis rs3785574 0.962 rs2727332 chr17:61878584 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.68 0.45 9.24e-8 Height; TGCT cis rs34014631 0.786 rs76228295 chr10:103685231 A/C cg22630918 chr10:102748988 C10orf2 0.42 4.78 0.39 4.86e-6 Coronary artery calcification; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.49 5.37 0.43 3.75e-7 Lymphocyte counts; TGCT cis rs9611565 0.694 rs202618 chr22:41822856 A/G cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT cis rs9399135 0.967 rs7750300 chr6:135350950 C/G cg24558204 chr6:135376177 HBS1L 0.49 5.0 0.41 1.88e-6 Red blood cell count; TGCT cis rs11167764 0.895 rs7734160 chr5:141473144 G/T cg08523384 chr5:141488047 NDFIP1 -0.24 -4.91 -0.4 2.85e-6 Crohn's disease; TGCT cis rs6740322 0.895 rs9309098 chr2:43554972 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.41 6.86 0.52 2.87e-10 Coronary artery disease; TGCT cis rs2851682 0.706 rs2727270 chr11:61603237 C/T cg20584555 chr11:61717780 BEST1 -0.35 -4.45 -0.37 1.87e-5 Gestational age at birth (child effect);Trans fatty acid levels; TGCT cis rs514406 0.825 rs487453 chr1:53271225 T/C cg01802117 chr1:53393560 SCP2 0.44 5.35 0.43 4.14e-7 Monocyte count; TGCT cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg13397359 chr6:42928475 GNMT 0.67 5.93 0.47 2.84e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2692947 0.673 rs4907299 chr2:96780122 G/T cg05933789 chr2:97190408 NA 0.17 4.66 0.39 7.93e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6951245 1.000 rs28379681 chr7:1070539 C/T cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs561341 0.714 rs7218466 chr17:30263314 A/G cg20587970 chr11:113659929 NA -0.83 -7.97 -0.58 8.86e-13 Hip circumference adjusted for BMI; TGCT cis rs1401999 1.000 rs3805108 chr3:183691650 T/C cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs11673344 0.543 rs1818748 chr19:37556318 T/C cg08039142 chr19:36980659 ZNF566 0.48 4.47 0.37 1.75e-5 Obesity-related traits; TGCT cis rs394563 0.591 rs237019 chr6:149727064 G/A cg03678062 chr6:149772716 ZC3H12D -0.38 -4.74 -0.39 5.83e-6 Dupuytren's disease; TGCT cis rs9457247 0.967 rs2757054 chr6:167380501 A/G cg25258033 chr6:167368657 RNASET2 -0.18 -4.49 -0.37 1.63e-5 Crohn's disease; TGCT cis rs68170813 0.559 rs1002935 chr7:106832361 G/A cg02696742 chr7:106810147 HBP1 -0.72 -6.05 -0.48 1.56e-8 Coronary artery disease; TGCT cis rs6867032 1.000 rs4398675 chr5:2015816 G/A cg26168224 chr5:2018326 NA 0.43 7.96 0.58 9.31e-13 Gut microbiome composition (winter); TGCT cis rs3091242 0.933 rs7541095 chr1:25761291 T/C cg10117171 chr1:25599238 RHD -0.32 -5.18 -0.42 8.61e-7 Erythrocyte sedimentation rate; TGCT cis rs17711722 0.640 rs13237956 chr7:65318029 G/A cg00343986 chr7:65444356 GUSB 0.26 6.14 0.48 1.02e-8 Calcium levels; TGCT cis rs78487399 0.908 rs55640722 chr2:43846040 A/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.65 4.58 0.38 1.12e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs62103177 0.810 rs62103192 chr18:77629050 A/T cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs9916302 0.904 rs4357971 chr17:37717280 C/T cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs3931020 0.548 rs969435 chr1:75273866 A/G cg17719053 chr1:75198211 TYW3;CRYZ -0.48 -5.12 -0.42 1.15e-6 Resistin levels; TGCT trans rs459571 1.000 rs467387 chr9:136907005 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.71 -7.47 -0.56 1.26e-11 Platelet distribution width; TGCT cis rs2084898 1.000 rs569044 chr11:119999191 A/G cg00437969 chr11:120009135 TRIM29 0.4 4.66 0.39 7.89e-6 Stroke (pediatric); TGCT cis rs10875746 0.951 rs8804 chr12:48541757 A/G cg20731937 chr12:48336164 NA 0.63 5.19 0.42 8.18e-7 Longevity (90 years and older); TGCT cis rs853679 0.550 rs1233707 chr6:28172953 G/A cg12963246 chr6:28129442 ZNF389 0.49 4.82 0.4 4.15e-6 Depression; TGCT cis rs9733 0.503 rs7556451 chr1:150913142 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Tonsillectomy; TGCT cis rs2404602 0.536 rs1587381 chr15:76769620 G/A cg26408565 chr15:76604113 ETFA -0.37 -4.99 -0.41 2.03e-6 Blood metabolite levels; TGCT cis rs3749237 0.595 rs1568661 chr3:49520958 A/G cg07636037 chr3:49044803 WDR6 0.63 5.9 0.47 3.22e-8 Resting heart rate; TGCT cis rs6701037 0.625 rs72719370 chr1:175128536 G/C cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT cis rs1878931 0.531 rs9635548 chr16:3417156 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.12 0.54 7.59e-11 Body mass index (adult); TGCT cis rs3820928 0.967 rs4675114 chr2:227768362 C/T cg11843606 chr2:227700838 RHBDD1 -0.51 -4.5 -0.37 1.52e-5 Pulmonary function; TGCT cis rs9894429 0.690 rs12949956 chr17:79542813 C/T cg21028142 chr17:79581711 NPLOC4 -0.3 -6.96 -0.53 1.79e-10 Eye color traits; TGCT cis rs1532993 0.518 rs12502451 chr4:98602932 C/T cg05340658 chr4:99064831 C4orf37 -0.42 -5.02 -0.41 1.72e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs6089829 0.925 rs6122086 chr20:61664528 T/C cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs6570726 0.902 rs4895678 chr6:145935510 C/T cg23711669 chr6:146136114 FBXO30 0.65 5.95 0.47 2.53e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs7193541 0.826 rs56143602 chr16:74694692 T/C cg01733217 chr16:74700730 RFWD3 0.81 7.76 0.57 2.74e-12 Multiple myeloma; TGCT cis rs7811142 1.000 rs1073 chr7:100031612 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs3125734 0.633 rs7088891 chr10:64034019 G/T cg05499367 chr10:63213510 TMEM26 -0.33 -4.52 -0.38 1.45e-5 Rheumatoid arthritis; TGCT trans rs4332037 0.539 rs56180486 chr7:2050747 C/T cg10840412 chr1:235813424 GNG4 0.96 6.89 0.53 2.47e-10 Bipolar disorder; TGCT cis rs7089973 0.584 rs4752255 chr10:116576790 C/T cg03647239 chr10:116582469 FAM160B1 0.6 5.5 0.44 2.03e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs453301 0.658 rs9329175 chr8:8866661 C/T cg06636001 chr8:8085503 FLJ10661 -0.64 -5.42 -0.44 2.93e-7 Joint mobility (Beighton score); TGCT cis rs587847 0.540 rs635200 chr15:37662390 T/G cg16890051 chr15:37175029 LOC145845 -0.37 -4.44 -0.37 1.95e-5 Intraocular pressure; TGCT cis rs6988636 0.584 rs73337885 chr8:124116300 A/G cg27053337 chr8:124217698 FAM83A 0.56 4.9 0.4 2.88e-6 Urinary uromodulin levels; TGCT cis rs7829975 0.533 rs13274028 chr8:8729193 A/C cg15556689 chr8:8085844 FLJ10661 0.78 7.58 0.56 6.92e-12 Mood instability; TGCT cis rs7954584 0.567 rs1169071 chr12:122390084 G/T cg22168489 chr12:122356033 WDR66 0.22 4.9 0.4 2.97e-6 Mean corpuscular volume; TGCT cis rs2153535 0.580 rs1932279 chr6:8473653 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs8014204 0.935 rs8010840 chr14:75355203 T/C cg06637938 chr14:75390232 RPS6KL1 -0.75 -7.25 -0.55 4e-11 Caffeine consumption; TGCT cis rs13424612 1.000 rs4854058 chr2:240923677 C/A cg26363272 chr2:240904871 NDUFA10 0.29 4.85 0.4 3.55e-6 Odorant perception (isobutyraldehyde); TGCT cis rs7659604 0.689 rs4283687 chr4:122663460 A/G cg19748678 chr4:122722346 EXOSC9 0.54 4.6 0.38 1.05e-5 Type 2 diabetes; TGCT cis rs6952808 0.825 rs34296663 chr7:1935245 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.53 -0.44 1.84e-7 Bipolar disorder and schizophrenia; TGCT cis rs4780401 0.609 rs35649585 chr16:11813899 G/A cg01061890 chr16:11836724 TXNDC11 -0.6 -5.82 -0.46 4.74e-8 Rheumatoid arthritis; TGCT cis rs28595532 0.844 rs115202072 chr4:119732458 C/T cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs12477438 0.520 rs13031919 chr2:99848932 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.98 11.89 0.73 3.21e-22 Chronic sinus infection; TGCT cis rs12579753 0.879 rs11115009 chr12:82165409 G/T cg21231944 chr12:82153410 PPFIA2 0.34 4.62 0.38 9.52e-6 Resting heart rate; TGCT cis rs10504229 0.683 rs56204590 chr8:58131642 T/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs651907 0.557 rs11924013 chr3:101366698 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 11.18 0.71 1.7e-20 Colorectal cancer; TGCT cis rs10479542 0.784 rs6601050 chr5:178986261 C/G cg09060608 chr5:178986726 RUFY1 -0.62 -7.74 -0.57 3.01e-12 Lung cancer; TGCT cis rs10875595 0.836 rs10067231 chr5:140673429 C/T cg24830062 chr5:140700576 TAF7 -0.61 -5.14 -0.42 1.04e-6 Pulmonary function decline; TGCT cis rs6570726 0.905 rs388728 chr6:145816419 T/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7027203 0.576 rs7848045 chr9:96551824 G/A cg14396892 chr9:96623032 NA 0.22 4.51 0.38 1.51e-5 DNA methylation (variation); TGCT cis rs853679 0.550 rs1233704 chr6:28166923 A/G cg12963246 chr6:28129442 ZNF389 -0.49 -4.72 -0.39 6.15e-6 Depression; TGCT cis rs12530845 1.000 rs60179239 chr7:135333028 A/G cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs42648 0.869 rs3810891 chr7:89908851 A/G cg25739043 chr7:89950458 NA -0.73 -7.29 -0.55 3.15e-11 Homocysteine levels; TGCT cis rs3008870 0.755 rs2815374 chr1:67507387 G/A cg08660285 chr1:67390436 MIER1;WDR78 0.8 7.94 0.58 1.06e-12 Lymphocyte percentage of white cells; TGCT cis rs12541335 0.615 rs4872464 chr8:22153381 G/A cg09517075 chr8:22133004 PIWIL2 0.24 4.57 0.38 1.18e-5 Hypertriglyceridemia; TGCT cis rs2730245 1.000 rs6965685 chr7:158726462 C/T cg11984989 chr7:158649758 WDR60 0.98 8.74 0.62 1.33e-14 Height; TGCT cis rs3749237 0.964 rs1799843 chr3:49849723 G/A cg10152585 chr3:50297680 NA 0.51 4.84 0.4 3.79e-6 Resting heart rate; TGCT cis rs12908161 1.000 rs11638290 chr15:85227636 C/T cg12863693 chr15:85201151 NMB 0.46 5.53 0.44 1.79e-7 Schizophrenia; TGCT trans rs4332037 0.851 rs10268609 chr7:1962163 A/C cg22232500 chr2:134024266 NCKAP5 0.84 6.66 0.51 8.03e-10 Bipolar disorder; TGCT cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg24531977 chr5:56204891 C5orf35 -0.76 -7.66 -0.57 4.53e-12 Initial pursuit acceleration; TGCT cis rs892961 1.000 rs1110638 chr17:75400690 T/C cg05865280 chr17:75406074 SEPT9 0.26 6.09 0.48 1.29e-8 Airflow obstruction; TGCT cis rs11249608 0.548 rs6867208 chr5:178455575 G/A cg23951258 chr5:178450506 ZNF879 0.45 4.61 0.38 9.7e-6 Pubertal anthropometrics; TGCT cis rs7666738 0.830 rs969048 chr4:98988921 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs853679 0.550 rs1150689 chr6:28165099 T/C cg12963246 chr6:28129442 ZNF389 0.48 4.74 0.39 5.69e-6 Depression; TGCT cis rs11785400 1.000 rs3735999 chr8:143746069 T/C cg24634471 chr8:143751801 JRK 0.55 5.92 0.47 2.93e-8 Schizophrenia; TGCT cis rs514406 0.607 rs1930305 chr1:53195481 G/T cg08859206 chr1:53392774 SCP2 0.34 4.82 0.4 4.1e-6 Monocyte count; TGCT cis rs11574514 1.000 rs79631436 chr16:67728369 T/A cg11238564 chr16:67218787 KIAA0895L;EXOC3L 0.71 4.54 0.38 1.33e-5 Crohn's disease; TGCT cis rs2439831 0.681 rs484029 chr15:43619560 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.69 0.62 1.84e-14 Lung cancer in ever smokers; TGCT cis rs3764400 0.567 rs1979897 chr17:46309546 C/T cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs11249608 0.548 rs10479520 chr5:178451447 C/A cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs911555 0.723 rs2273701 chr14:103923225 G/T cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs74233809 1.000 rs79082900 chr10:104877302 T/C cg05855489 chr10:104503620 C10orf26 0.84 4.47 0.37 1.71e-5 Birth weight; TGCT cis rs1568889 0.838 rs11030265 chr11:28296168 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.93 10.99 0.7 4.8e-20 Bipolar disorder; TGCT cis rs7312933 0.558 rs61926593 chr12:42818912 C/T cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.54 5.14 0.42 1.06e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2243480 1.000 rs35046236 chr7:65408613 T/C cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT trans rs3808502 0.563 rs12549144 chr8:11422861 C/G cg15556689 chr8:8085844 FLJ10661 0.8 7.37 0.55 2.09e-11 Neuroticism; TGCT cis rs1949733 0.628 rs2688231 chr4:8490981 G/A cg13073564 chr4:8508604 NA -0.45 -5.09 -0.42 1.32e-6 Response to antineoplastic agents; TGCT cis rs7772486 0.846 rs9373482 chr6:146363123 A/C cg05347473 chr6:146136440 FBXO30 0.57 5.51 0.44 2.02e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.904 rs12452509 chr17:37574722 G/A cg07936489 chr17:37558343 FBXL20 -0.65 -4.98 -0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs4900538 0.819 rs72698591 chr14:102838896 G/A cg18135206 chr14:102964638 TECPR2 -0.2 -4.76 -0.39 5.3e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs586688 0.625 rs567337 chr1:201652979 G/A cg07139329 chr1:201708558 NAV1 -0.51 -5.18 -0.42 8.82e-7 Obesity-related traits; TGCT cis rs3733606 0.775 rs66514314 chr4:6827238 C/T cg18375902 chr4:7764949 AFAP1;LOC84740 0.26 4.58 0.38 1.13e-5 Platelet count; TGCT cis rs9868809 0.881 rs2310996 chr3:48671834 T/C cg00383909 chr3:49044727 WDR6 0.82 4.5 0.37 1.55e-5 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7937682 0.889 rs559482 chr11:111497902 G/A cg09085632 chr11:111637200 PPP2R1B -1.09 -11.3 -0.71 8.63e-21 Primary sclerosing cholangitis; TGCT cis rs2404602 0.692 rs4360890 chr15:77173295 G/A cg22467129 chr15:76604101 ETFA -0.47 -5.39 -0.44 3.44e-7 Blood metabolite levels; TGCT cis rs7666738 0.830 rs6532701 chr4:98745134 C/T cg17366294 chr4:99064904 C4orf37 0.65 6.75 0.52 5.05e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9388451 0.839 rs10457469 chr6:126083658 G/A cg05901451 chr6:126070800 HEY2 -1.02 -15.06 -0.8 8.77e-30 Brugada syndrome; TGCT cis rs208520 1.000 rs72882100 chr6:66981495 G/C cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs6543140 0.964 rs2310301 chr2:103072935 C/T cg09003973 chr2:102972529 NA 0.55 4.67 0.39 7.71e-6 Blood protein levels; TGCT cis rs13326165 0.715 rs66462821 chr3:52390555 C/T cg27565382 chr3:53032988 SFMBT1 0.37 4.93 0.41 2.55e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs3818285 0.959 rs492943 chr10:111629030 A/T cg00817464 chr10:111662876 XPNPEP1 0.28 4.48 0.37 1.67e-5 Superior crus of antihelix expression; TGCT cis rs1865760 0.566 rs7772312 chr6:26049616 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.1e-11 Height; TGCT cis rs889312 0.500 rs252920 chr5:56148741 C/A cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs4523957 0.651 rs8082485 chr17:2060407 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3733585 0.699 rs12498956 chr4:9950705 G/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.46 -0.56 1.29e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6121246 0.567 rs6058187 chr20:30190923 T/C cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT trans rs797680 0.856 rs602204 chr1:93727579 A/G cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2820315 1.000 rs2494115 chr1:201832864 G/C cg12730843 chr1:201915899 LMOD1 -0.27 -4.8 -0.4 4.44e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs9467711 0.606 rs2073527 chr6:26374978 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.729 rs2413646 chr22:41906325 C/T cg13695892 chr22:41940480 POLR3H -0.91 -8.67 -0.61 1.97e-14 Vitiligo; TGCT cis rs2576037 0.623 rs2571000 chr18:44580347 G/A cg23302884 chr18:44338147 ST8SIA5 0.47 5.47 0.44 2.43e-7 Personality dimensions; TGCT cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT cis rs4319547 0.741 rs4758663 chr12:122939483 A/G cg05707623 chr12:122985044 ZCCHC8 -0.62 -5.02 -0.41 1.72e-6 Body mass index; TGCT trans rs877282 0.945 rs17293517 chr10:778770 C/T cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs12497850 0.864 rs4279134 chr3:49156676 A/G cg18654377 chr3:49208889 KLHDC8B -0.38 -4.76 -0.39 5.31e-6 Parkinson's disease; TGCT cis rs2562456 1.000 rs2359155 chr19:21671869 C/A cg25650185 chr19:21324782 ZNF431 0.58 4.96 0.41 2.31e-6 Pain; TGCT cis rs769267 0.965 rs4808937 chr19:19398005 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs3858526 0.874 rs10838879 chr11:5950169 C/T cg05234568 chr11:5960015 NA -0.48 -4.77 -0.39 5.08e-6 DNA methylation (variation); TGCT cis rs734999 0.566 rs12748729 chr1:2558740 C/T cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs9311474 0.652 rs614288 chr3:52220203 T/C cg07507251 chr3:52567010 NT5DC2 0.35 4.56 0.38 1.19e-5 Electroencephalogram traits; TGCT cis rs736408 0.677 rs2286798 chr3:52821177 G/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.59 -5.54 -0.45 1.7e-7 Bipolar disorder; TGCT cis rs754133 0.963 rs12319419 chr12:54420776 G/C cg16264616 chr12:54390824 NA 0.32 4.81 0.4 4.26e-6 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs6450176 0.625 rs3776726 chr5:53290052 T/A ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.58 -0.45 1.45e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs12134133 1.000 rs61822674 chr1:207436723 T/C cg02152968 chr1:207494213 CD55 0.61 4.66 0.39 7.94e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT trans rs9859260 0.744 rs539816 chr3:195784076 T/A cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs13256369 0.802 rs13280101 chr8:8562773 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs3796352 1.000 rs35174175 chr3:53041509 T/C cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs797680 0.856 rs682514 chr1:93719430 A/C cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs11948739 0.576 rs11242051 chr5:130261276 G/A cg08523029 chr5:130500466 HINT1 0.58 4.75 0.39 5.41e-6 Pediatric bone mineral content (hip); TGCT cis rs2019216 0.502 rs1842113 chr17:21872137 G/A cg22648282 chr17:21454238 C17orf51 -0.56 -5.48 -0.44 2.25e-7 Pelvic organ prolapse; TGCT cis rs992157 0.932 rs4672884 chr2:219182481 G/A cg00012203 chr2:219082015 ARPC2 -0.7 -7.0 -0.53 1.39e-10 Colorectal cancer; TGCT cis rs769267 1.000 rs769267 chr19:19446936 A/G cg19010396 chr19:19431384 KIAA0892;SF4 0.6 4.95 0.41 2.39e-6 Tonsillectomy; TGCT cis rs2980439 0.818 rs2948300 chr8:8106508 C/T cg15556689 chr8:8085844 FLJ10661 0.88 8.8 0.62 9.78e-15 Neuroticism; TGCT cis rs9467773 1.000 rs6940188 chr6:26562029 G/C cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs17802743 chr8:58105897 C/T cg02725872 chr8:58115012 NA -0.4 -4.86 -0.4 3.44e-6 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.935 rs446242 chr6:145843866 A/G cg23711669 chr6:146136114 FBXO30 0.66 6.39 0.5 3.08e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6430585 0.528 rs111682961 chr2:136653848 C/T cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs10504229 0.683 rs35889486 chr8:58117749 T/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs861020 1.000 rs595918 chr1:209966843 A/G cg05527609 chr1:210001259 C1orf107 0.9 7.62 0.56 5.54e-12 Orofacial clefts; TGCT cis rs6815814 0.950 rs5743566 chr4:38805942 G/C cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs12142240 0.698 rs72886907 chr1:46814265 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.4e-6 Menopause (age at onset); TGCT cis rs9911578 0.933 rs2531725 chr17:56517962 G/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.16 -0.48 9.42e-9 Intelligence (multi-trait analysis); TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg00024416 chr22:24240387 NA 0.33 5.64 0.45 1.09e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg06634786 chr22:41940651 POLR3H 0.9 8.62 0.61 2.67e-14 Vitiligo; TGCT cis rs2842992 0.672 rs7738253 chr6:160193917 G/T cg11366901 chr6:160182831 ACAT2 0.98 6.47 0.5 2e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs7937682 0.824 rs11213962 chr11:111506027 G/A cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs6688613 0.649 rs2280995 chr1:166846069 A/G cg07049167 chr1:166818506 POGK 0.25 5.23 0.43 6.88e-7 Refractive astigmatism; TGCT cis rs7647973 1.000 rs6785045 chr3:49435243 G/C cg05785598 chr3:49045655 WDR6 -0.4 -4.67 -0.39 7.57e-6 Menarche (age at onset); TGCT cis rs35306767 0.903 rs11253485 chr10:919362 C/T cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs9311474 0.629 rs7639267 chr3:52568805 G/T cg07507251 chr3:52567010 NT5DC2 0.49 7.22 0.54 4.7e-11 Electroencephalogram traits; TGCT cis rs1865760 0.713 rs7766342 chr6:25990674 C/A cg16482183 chr6:26056742 HIST1H1C 0.54 4.77 0.39 5.15e-6 Height; TGCT trans rs6089829 1.000 rs6089829 chr20:61669036 C/T cg23505145 chr19:12996616 KLF1 -0.84 -8.83 -0.62 8.17e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs6570726 0.935 rs12663211 chr6:145818427 G/A cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1801251 1.000 rs71421663 chr2:233619131 A/G cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs6912958 0.781 rs2284908 chr6:88194500 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.92 -0.4 2.67e-6 Monocyte percentage of white cells; TGCT cis rs11718455 1.000 rs3856744 chr3:44045812 T/C cg08738300 chr3:44038990 NA 0.82 5.68 0.45 9.03e-8 Coronary artery disease; TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg17178900 chr1:205818956 PM20D1 -0.53 -6.55 -0.51 1.39e-9 Monocyte percentage of white cells; TGCT cis rs6540559 0.546 rs57315825 chr1:210030197 C/T cg12034118 chr1:209979487 IRF6 0.67 4.74 0.39 5.85e-6 Cleft lip with or without cleft palate; TGCT cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg13770153 chr20:60521292 NA -0.54 -7.35 -0.55 2.36e-11 Body mass index; TGCT cis rs4727027 0.933 rs12667123 chr7:148850621 G/A cg23583168 chr7:148888333 NA -0.77 -10.1 -0.67 7.35e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs3780486 0.505 rs10758188 chr9:33123386 C/T cg20290983 chr6:43655470 MRPS18A -0.78 -8.21 -0.59 2.38e-13 IgG glycosylation; TGCT cis rs6940638 0.688 rs7764984 chr6:27034181 A/G cg15659132 chr6:26577336 NA -0.56 -4.99 -0.41 1.97e-6 Intelligence (multi-trait analysis); TGCT cis rs66573146 1.000 rs7675281 chr4:7002120 C/T cg01220768 chr4:7056774 TADA2B 0.41 4.88 0.4 3.16e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs56104184 0.775 rs56149557 chr19:49401384 C/A cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7681440 0.869 rs7680557 chr4:90763360 C/A cg20003494 chr4:90757398 SNCA -0.63 -6.09 -0.48 1.3e-8 Dementia with Lewy bodies; TGCT cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg17554472 chr22:41940697 POLR3H -0.42 -4.56 -0.38 1.19e-5 Vitiligo; TGCT cis rs9398235 0.929 rs4945860 chr6:110728383 A/G cg19196401 chr6:110721138 DDO 0.49 4.62 0.38 9.53e-6 Systemic lupus erythematosus; TGCT cis rs9910055 0.762 rs1135215 chr17:42253519 T/C cg19774624 chr17:42201019 HDAC5 -0.84 -8.44 -0.6 7.03e-14 Total body bone mineral density; TGCT cis rs9650657 0.571 rs4240673 chr8:10787612 T/C cg27411982 chr8:10470053 RP1L1 -0.23 -4.93 -0.4 2.56e-6 Neuroticism; TGCT cis rs6912958 0.754 rs2268994 chr6:88185386 A/T cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -5.02 -0.41 1.72e-6 Monocyte percentage of white cells; TGCT cis rs763014 0.966 rs12935215 chr16:670605 T/C cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.15e-6 Height; TGCT cis rs3777722 0.688 rs2757045 chr6:167350963 C/T cg06783166 chr6:167814257 NA -0.28 -4.48 -0.37 1.67e-5 Spontaneous preterm birth (preterm birth); TGCT cis rs801193 0.967 rs3800823 chr7:66147110 C/A cg00343986 chr7:65444356 GUSB -0.21 -4.59 -0.38 1.06e-5 Aortic root size; TGCT cis rs6500602 0.701 rs4785969 chr16:4536934 A/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.41 7.48 0.56 1.16e-11 Schizophrenia; TGCT trans rs2727020 0.521 rs10839299 chr11:49573981 C/T cg11707556 chr5:10655725 ANKRD33B -0.42 -8.32 -0.6 1.37e-13 Coronary artery disease; TGCT cis rs12682352 0.652 rs1567398 chr8:8726804 A/C cg17143192 chr8:8559678 CLDN23 -0.47 -4.95 -0.41 2.39e-6 Neuroticism; TGCT cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg05025164 chr4:1340916 KIAA1530 0.51 4.48 0.37 1.65e-5 Longevity; TGCT cis rs60154123 0.730 rs12403947 chr1:210456524 A/G cg04352962 chr1:209979756 IRF6 -0.65 -4.74 -0.39 5.67e-6 Coronary artery disease; TGCT cis rs2204008 0.870 rs12369578 chr12:38444227 C/T cg13010199 chr12:38710504 ALG10B 0.56 4.44 0.37 2e-5 Bladder cancer; TGCT cis rs17376456 0.825 rs10054903 chr5:93281491 C/A cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg03806693 chr22:41940476 POLR3H 1.08 11.99 0.73 1.84e-22 Vitiligo; TGCT cis rs9549260 0.564 rs4245402 chr13:41287540 C/T cg21288729 chr13:41239152 FOXO1 0.94 9.06 0.63 2.41e-15 Red blood cell count; TGCT cis rs478304 0.651 rs7110576 chr11:65512057 T/G cg17480646 chr11:65405466 SIPA1 -0.57 -6.93 -0.53 2.03e-10 Acne (severe); TGCT cis rs72634258 0.519 rs2071984 chr1:7928656 C/T cg26816564 chr1:7831052 VAMP3 0.62 4.99 0.41 1.98e-6 Inflammatory bowel disease; TGCT cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg20203395 chr5:56204925 C5orf35 -0.75 -5.9 -0.47 3.19e-8 Initial pursuit acceleration; TGCT cis rs28595532 0.920 rs114544767 chr4:119728364 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs11190604 0.767 rs7090150 chr10:102173446 G/T cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9303401 0.659 rs7225896 chr17:56637337 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.954 rs6060978 chr20:30416893 G/A cg13852791 chr20:30311386 BCL2L1 0.76 5.65 0.45 1.06e-7 Mean corpuscular hemoglobin; TGCT cis rs3813359 0.614 rs12202999 chr6:130751454 A/G cg25049486 chr6:130544510 SAMD3 0.37 4.48 0.37 1.66e-5 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9297145 0.565 rs7794690 chr7:98764768 G/A cg05967295 chr7:98741636 SMURF1 -0.66 -8.35 -0.6 1.13e-13 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs11779988 0.545 rs375203 chr8:17769054 T/A cg01800426 chr8:17659068 MTUS1 -0.73 -5.71 -0.46 7.76e-8 Breast cancer; TGCT cis rs7100689 0.784 rs7089058 chr10:82071263 T/C cg01528321 chr10:82214614 TSPAN14 0.8 8.0 0.58 7.5e-13 Post bronchodilator FEV1; TGCT cis rs2063714 0.532 rs2063713 chr6:157196299 G/T cg23222435 chr6:157204239 ARID1B -0.46 -7.45 -0.56 1.38e-11 Sitting height ratio; TGCT cis rs7714584 1.000 rs11747065 chr5:150295486 C/T cg22134413 chr5:150180641 NA 1.01 7.24 0.55 4.17e-11 Crohn's disease; TGCT trans rs6089829 0.962 rs6122347 chr20:61661866 C/T cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs2832191 0.647 rs11170 chr21:30378090 C/T cg08807101 chr21:30365312 RNF160 0.6 5.88 0.47 3.5e-8 Dental caries; TGCT cis rs1062177 0.756 rs2964592 chr5:151115688 A/G cg12924095 chr5:151150029 G3BP1 -0.33 -4.75 -0.39 5.62e-6 Preschool internalizing problems; TGCT cis rs6840360 0.967 rs4383600 chr4:152694383 T/C cg22705602 chr4:152727874 NA -0.24 -4.55 -0.38 1.24e-5 Intelligence (multi-trait analysis); TGCT cis rs12188164 0.686 rs72711367 chr5:418494 A/G cg22025206 chr5:502436 SLC9A3 -0.26 -4.59 -0.38 1.06e-5 Cystic fibrosis severity; TGCT cis rs981844 0.712 rs6535957 chr4:154749862 C/A cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs7246657 0.943 rs7253091 chr19:37967214 C/T cg18154014 chr19:37997991 ZNF793 0.73 5.33 0.43 4.4e-7 Coronary artery calcification; TGCT cis rs1865760 0.865 rs10946800 chr6:25957773 C/T cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs3796352 0.571 rs11713926 chr3:53155072 C/T cg07884673 chr3:53033167 SFMBT1 0.56 6.14 0.48 1.04e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs12220238 1.000 rs12220238 chr10:75952670 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.28 0.55 3.4e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs6089829 0.962 rs4997812 chr20:61663153 T/G cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs12110303 1 rs12110303 chr5:90662839 G/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 9.14 0.63 1.53e-15 Breast cancer; TGCT cis rs10992471 0.603 rs7033979 chr9:95223980 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.74 -0.46 6.79e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2456568 0.778 rs2456563 chr11:93678675 C/T cg17595323 chr11:93583763 C11orf90 -0.4 -5.12 -0.42 1.13e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs11153730 0.503 rs445099 chr6:118618252 T/C cg21191810 chr6:118973309 C6orf204 0.27 4.55 0.38 1.27e-5 QT interval;Heart rate;QRS duration;QRS complex (Sokolow-Lyon); TGCT cis rs9894429 0.634 rs11655346 chr17:79572399 A/G cg21028142 chr17:79581711 NPLOC4 -0.29 -5.95 -0.47 2.56e-8 Eye color traits; TGCT cis rs7412746 0.634 rs12409208 chr1:150860055 A/G cg09365446 chr1:150670422 GOLPH3L 0.35 5.0 0.41 1.87e-6 Melanoma; TGCT trans rs8073060 0.544 rs225258 chr17:33956883 C/T cg19694781 chr19:47549865 TMEM160 -0.62 -14.07 -0.78 1.86e-27 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7829975 0.523 rs9644774 chr8:8559832 G/A cg15556689 chr8:8085844 FLJ10661 -0.54 -4.55 -0.38 1.27e-5 Mood instability; TGCT cis rs6599388 1.000 rs6599388 chr4:939087 C/T cg17500754 chr4:1581635 NA 0.33 4.68 0.39 7.49e-6 Parkinson's disease; TGCT cis rs644799 1.000 rs514170 chr11:95556696 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6880778 0.505 rs6891952 chr5:40400885 C/T cg01087697 chr5:40835557 RPL37 0.54 4.93 0.4 2.6e-6 Inflammatory bowel disease; TGCT cis rs780096 0.526 rs809058 chr2:27616790 T/C cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.46 -0.37 1.84e-5 Total body bone mineral density; TGCT cis rs7809950 0.678 rs982447 chr7:106973534 T/C cg23024343 chr7:107201750 COG5 -0.42 -5.67 -0.45 9.29e-8 Coronary artery disease; TGCT cis rs67073037 0.955 rs4371318 chr2:29156360 T/C cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT trans rs3780486 0.801 rs3780495 chr9:33125942 A/C cg20290983 chr6:43655470 MRPS18A 1.19 14.71 0.8 5.8e-29 IgG glycosylation; TGCT cis rs1997103 1.000 rs10224446 chr7:55413147 C/G cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg12310025 chr6:25882481 NA -0.75 -6.87 -0.52 2.79e-10 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs76944716 chr8:58191643 T/C cg21724239 chr8:58056113 NA 0.38 5.14 0.42 1.02e-6 Developmental language disorder (linguistic errors); TGCT cis rs9926296 0.632 rs7206546 chr16:89799079 C/T cg27121462 chr16:89883253 FANCA -0.53 -5.01 -0.41 1.87e-6 Vitiligo; TGCT cis rs35306767 0.633 rs17221491 chr10:1065191 A/G cg26597838 chr10:835615 NA 0.57 6.32 0.49 4.34e-9 Eosinophil percentage of granulocytes; TGCT cis rs10791323 0.546 rs55801927 chr11:133713094 A/C cg15485101 chr11:133734466 NA 0.39 5.18 0.42 8.85e-7 Childhood ear infection; TGCT trans rs7698623 0.850 rs7676119 chr4:88780778 G/A cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs11741688 0.557 rs6898923 chr5:178330559 C/T cg08270223 chr5:178322770 ZFP2 -0.37 -5.49 -0.44 2.14e-7 Sleep duration; TGCT cis rs12580194 0.957 rs12579451 chr12:55694116 C/T cg20672549 chr12:56432144 IKZF4 0.29 4.61 0.38 9.79e-6 Cancer; TGCT cis rs497273 0.553 rs508595 chr12:121198891 C/G cg02419362 chr12:121203948 SPPL3 0.19 4.52 0.38 1.43e-5 Systemic lupus erythematosus; TGCT cis rs6570726 0.875 rs416243 chr6:145868081 A/T cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg07507251 chr3:52567010 NT5DC2 0.42 5.89 0.47 3.41e-8 Bipolar disorder; TGCT cis rs77106637 0.932 rs2886599 chr11:72721271 C/A cg03713592 chr11:72463424 ARAP1 0.81 5.14 0.42 1.05e-6 Type 2 diabetes; TGCT cis rs10876993 0.715 rs2169987 chr12:58012111 G/A cg15848620 chr12:58087721 OS9 0.68 4.93 0.4 2.6e-6 Celiac disease or Rheumatoid arthritis; TGCT cis rs11785400 0.793 rs4736367 chr8:143742477 G/A cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs2242116 0.796 rs4683297 chr3:46973673 T/C cg23352942 chr3:46931381 PTH1R 0.31 4.53 0.38 1.36e-5 Birth weight; TGCT cis rs6912958 0.631 rs9450704 chr6:88182704 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.54 -5.23 -0.43 7.03e-7 Monocyte percentage of white cells; TGCT cis rs10832963 1.000 rs10128711 chr11:18632984 A/G cg09201001 chr11:18656081 SPTY2D1 1.02 11.0 0.7 4.62e-20 Breast cancer; TGCT cis rs6674176 0.660 rs3791112 chr1:44379248 T/G cg12908607 chr1:44402522 ARTN -0.72 -9.08 -0.63 2.12e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs4665809 0.887 rs2384324 chr2:26354239 A/G cg22920501 chr2:26401640 FAM59B -0.7 -6.22 -0.49 6.98e-9 Gut microbiome composition (summer); TGCT cis rs6688613 0.685 rs10918600 chr1:166919342 C/T cg07049167 chr1:166818506 POGK -0.24 -5.09 -0.42 1.31e-6 Refractive astigmatism; TGCT cis rs1008375 1.000 rs7694020 chr4:17682597 C/T cg10189774 chr4:17578691 LAP3 0.55 5.22 0.42 7.45e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3733585 0.781 rs13103690 chr4:9972778 T/G cg00071950 chr4:10020882 SLC2A9 -0.63 -7.92 -0.58 1.15e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1784581 0.588 rs1784606 chr6:162405992 A/T cg17173639 chr6:162384350 PARK2 -0.39 -6.68 -0.51 7.2e-10 Itch intensity from mosquito bite; TGCT cis rs832540 0.864 rs252908 chr5:56120686 T/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Coronary artery disease; TGCT cis rs2120019 0.938 rs2120020 chr15:75316845 T/C cg11632617 chr15:75315747 PPCDC -0.3 -4.44 -0.37 1.95e-5 Blood trace element (Zn levels); TGCT cis rs62244186 0.606 rs6798590 chr3:44556861 T/A cg11003573 chr3:44754125 ZNF502 -0.41 -4.51 -0.38 1.51e-5 Depressive symptoms; TGCT cis rs9300255 0.602 rs1617434 chr12:123649486 A/G cg00376283 chr12:123451042 ABCB9 0.72 4.96 0.41 2.29e-6 Neutrophil percentage of white cells; TGCT cis rs7674212 0.865 rs1481279 chr4:103977938 A/T cg16532752 chr4:104119610 CENPE 0.5 4.55 0.38 1.26e-5 Type 2 diabetes; TGCT cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.97 10.44 0.68 1.06e-18 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.744 rs164747 chr16:89708680 T/G cg04287289 chr16:89883240 FANCA -0.51 -4.81 -0.4 4.28e-6 Vitiligo; TGCT cis rs3026101 0.671 rs1143206 chr17:5284698 A/G cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.68 0.39 7.51e-6 Body mass index; TGCT cis rs10986311 0.775 rs11791153 chr9:127166457 C/G cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -4.57 -0.38 1.17e-5 Vitiligo; TGCT cis rs9341808 0.718 rs9443734 chr6:80820293 C/T cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs7267979 1.000 rs2856 chr20:25433536 T/C cg03522245 chr20:25566470 NINL 0.62 6.56 0.51 1.34e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2486288 0.656 rs12904150 chr15:45547605 T/C cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs769267 0.965 rs8101938 chr19:19390497 G/A cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs2204008 0.775 rs3900361 chr12:38238936 A/G cg13010199 chr12:38710504 ALG10B -0.59 -4.54 -0.38 1.29e-5 Bladder cancer; TGCT cis rs908922 0.676 rs7531317 chr1:152528439 A/C cg20991723 chr1:152506922 NA 0.44 5.96 0.47 2.44e-8 Hair morphology; TGCT cis rs2153535 0.580 rs1932283 chr6:8477661 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg22168489 chr12:122356033 WDR66 -0.24 -5.98 -0.47 2.26e-8 Mean corpuscular volume; TGCT cis rs875971 0.660 rs6460308 chr7:66084740 T/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.17e-7 Aortic root size; TGCT cis rs910316 1.000 rs10146482 chr14:75574087 C/T cg11812906 chr14:75593930 NEK9 0.74 7.44 0.56 1.43e-11 Height; TGCT cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg13695892 chr22:41940480 POLR3H -0.89 -8.37 -0.6 1.03e-13 Vitiligo; TGCT cis rs12210905 0.688 rs72845025 chr6:27524443 G/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7223966 1.000 rs7211213 chr17:61769456 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.05 0.41 1.51e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs1532993 0.518 rs877376 chr4:98625497 A/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs12701220 0.894 rs10257744 chr7:1045612 C/T cg27454412 chr7:1067447 C7orf50 -0.48 -4.47 -0.37 1.75e-5 Bronchopulmonary dysplasia; TGCT cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg17554472 chr22:41940697 POLR3H -0.49 -5.06 -0.41 1.46e-6 Vitiligo; TGCT cis rs7666738 0.830 rs13101766 chr4:98957696 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1775715 0.677 rs2799034 chr10:32175896 A/G cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs7267979 0.844 rs4815413 chr20:25359229 G/T cg14121845 chr20:25566513 NINL -0.45 -4.6 -0.38 1.02e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs71435601 0.628 rs1367120 chr2:21386304 T/C cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs4699052 1.000 rs6533059 chr4:104133376 T/G cg16532752 chr4:104119610 CENPE -0.6 -5.61 -0.45 1.28e-7 Testicular germ cell tumor; TGCT cis rs360798 0.512 rs2430388 chr2:63106784 T/C cg17519650 chr2:63277830 OTX1 0.62 5.64 0.45 1.09e-7 Coronary artery disease; TGCT cis rs67311347 1.000 rs2305521 chr3:40429183 A/G cg13683864 chr3:40499215 RPL14 -1.05 -11.13 -0.71 2.2e-20 Renal cell carcinoma; TGCT cis rs875971 0.706 rs1643374 chr7:65872682 T/A cg18876405 chr7:65276391 NA 0.41 6.26 0.49 5.83e-9 Aortic root size; TGCT cis rs9611565 0.681 rs132918 chr22:41808350 C/T cg06481639 chr22:41940642 POLR3H 0.59 5.38 0.44 3.56e-7 Vitiligo; TGCT cis rs9393777 0.778 rs67457459 chr6:27198343 T/G cg10876282 chr6:28092338 ZSCAN16 0.71 4.62 0.38 9.6e-6 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.754 rs702304 chr6:145990797 A/G cg23711669 chr6:146136114 FBXO30 -0.93 -10.56 -0.69 5.5e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6952808 0.542 rs10243920 chr7:1950385 G/A cg22963979 chr7:1858916 MAD1L1 -0.38 -5.8 -0.46 5.26e-8 Bipolar disorder and schizophrenia; TGCT cis rs2380220 0.606 rs9488080 chr6:96006973 A/G cg04719120 chr6:96025338 MANEA 0.62 4.94 0.41 2.44e-6 Behavioural disinhibition (generation interaction); TGCT cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg03609598 chr5:56110824 MAP3K1 -0.56 -4.57 -0.38 1.14e-5 Initial pursuit acceleration; TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs7666738 0.579 rs7672718 chr4:98645122 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.74 0.39 5.77e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.850 rs2439832 chr15:43779686 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.76 5.22 0.42 7.24e-7 Lung cancer in ever smokers; TGCT cis rs597539 0.652 rs674654 chr11:68698762 G/T cg21963583 chr11:68658836 MRPL21 0.35 5.8 0.46 5.09e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs10504229 1.000 rs76270388 chr8:58195605 T/A cg08280861 chr8:58055591 NA 0.36 4.61 0.38 9.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs2549003 1.000 rs2070725 chr5:131821788 C/T cg02551604 chr5:131831745 NA -0.9 -12.1 -0.74 9.75e-23 Asthma (sex interaction); TGCT cis rs7246657 0.943 rs13343502 chr19:37962292 C/T cg18154014 chr19:37997991 ZNF793 0.95 6.52 0.51 1.58e-9 Coronary artery calcification; TGCT cis rs12210905 0.688 rs9393814 chr6:27372978 C/T cg08851530 chr6:28072375 NA 1.33 5.85 0.47 4.08e-8 Hip circumference adjusted for BMI; TGCT cis rs1572072 0.593 rs3814787 chr13:24152370 G/C cg06150803 chr13:24144257 TNFRSF19 0.41 4.89 0.4 3.01e-6 Nasopharyngeal carcinoma; TGCT cis rs11122272 0.735 rs2024878 chr1:231528415 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.61 5.82 0.46 4.71e-8 Hemoglobin concentration; TGCT trans rs62103177 1.000 rs62103177 chr18:77624479 G/A cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs35883536 0.647 rs1995142 chr1:101041174 G/A cg06223162 chr1:101003688 GPR88 0.42 7.96 0.58 9.22e-13 Monocyte count; TGCT trans rs561341 0.941 rs2470236 chr17:30304940 G/C cg20587970 chr11:113659929 NA -1.05 -12.74 -0.75 2.84e-24 Hip circumference adjusted for BMI; TGCT cis rs709400 0.628 rs12889639 chr14:103860206 G/A cg26031613 chr14:104095156 KLC1 -0.83 -9.22 -0.64 9.94e-16 Body mass index; TGCT trans rs1974653 0.672 rs2904565 chr22:20091628 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg13695892 chr22:41940480 POLR3H -0.79 -7.55 -0.56 8.2e-12 Vitiligo; TGCT cis rs35306767 0.953 rs12354639 chr10:963681 G/A cg18964960 chr10:1102726 WDR37 0.57 4.55 0.38 1.27e-5 Eosinophil percentage of granulocytes; TGCT cis rs12541335 0.692 rs2290274 chr8:22214374 C/T cg18135555 chr8:22132992 PIWIL2 0.3 6.07 0.48 1.41e-8 Hypertriglyceridemia; TGCT cis rs875971 0.522 rs1617484 chr7:65463095 G/A cg18876405 chr7:65276391 NA 0.43 6.91 0.53 2.26e-10 Aortic root size; TGCT cis rs6088590 1.000 rs6119524 chr20:33373813 C/T cg24642439 chr20:33292090 TP53INP2 0.69 6.13 0.48 1.09e-8 Coronary artery disease; TGCT cis rs35306767 0.761 rs12770173 chr10:1027108 A/C cg26597838 chr10:835615 NA 0.58 6.55 0.51 1.35e-9 Eosinophil percentage of granulocytes; TGCT cis rs11514810 1.000 rs11514810 chr7:1428476 C/T cg24899294 chr7:1481343 MICALL2 -0.39 -5.5 -0.44 2.04e-7 Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder; TGCT cis rs7611238 0.560 rs7622180 chr3:195003633 A/T cg27323046 chr3:195102265 ACAP2 -0.37 -4.99 -0.41 1.96e-6 Body mass index; TGCT cis rs858239 0.539 rs57864591 chr7:23184424 T/A cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs12142240 0.698 rs17357628 chr1:46808462 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs4253772 0.591 rs7286155 chr22:46714735 A/G cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs28595532 0.841 rs17258907 chr4:119769905 A/G cg14228332 chr4:119757509 SEC24D 1.3 6.62 0.51 9.62e-10 Cannabis dependence symptom count; TGCT cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg03806693 chr22:41940476 POLR3H -1.11 -12.56 -0.75 7.44e-24 Vitiligo; TGCT cis rs314370 0.951 rs12666989 chr7:100486754 G/C cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs7236492 0.688 rs76247824 chr18:77186287 G/A cg15644404 chr18:77186268 NFATC1 -0.35 -4.67 -0.39 7.83e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs854765 0.583 rs5002487 chr17:17832460 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.89 0.58 1.36e-12 Total body bone mineral density; TGCT cis rs9993613 1.000 rs753944 chr4:73449917 T/C cg15102770 chr4:73434591 ADAMTS3 -0.5 -4.58 -0.38 1.09e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs9911578 0.835 rs2301867 chr17:56480074 T/A cg05425664 chr17:57184151 TRIM37 0.61 5.73 0.46 7.03e-8 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.66 -7.59 -0.56 6.5e-12 Height; TGCT cis rs826838 0.967 rs826858 chr12:39116731 A/G cg13010199 chr12:38710504 ALG10B -0.64 -5.07 -0.41 1.39e-6 Heart rate; TGCT cis rs1215050 0.740 rs783963 chr4:98989070 A/G cg17366294 chr4:99064904 C4orf37 0.54 5.6 0.45 1.3e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9303401 0.659 rs8074016 chr17:56840587 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs2354432 0.891 rs2165743 chr1:146690319 C/T cg25205988 chr1:146714368 CHD1L 1.24 7.08 0.54 9.53e-11 Mitochondrial DNA levels; TGCT cis rs926938 0.584 rs6689326 chr1:115369112 T/A cg12756093 chr1:115239321 AMPD1 -0.41 -6.02 -0.48 1.79e-8 Autism; TGCT cis rs6951245 0.882 rs56048221 chr7:1092533 A/G cg18402987 chr7:1209562 NA 0.56 5.06 0.41 1.47e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg22166914 chr1:53195759 ZYG11B 0.32 5.25 0.43 6.28e-7 Monocyte count; TGCT cis rs208520 0.909 rs62414636 chr6:67015723 T/G cg07460842 chr6:66804631 NA 0.69 5.72 0.46 7.53e-8 Exhaled nitric oxide output; TGCT cis rs9911578 0.935 rs2567912 chr17:56731270 T/C cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs832540 0.966 rs252925 chr5:56203773 G/A cg24531977 chr5:56204891 C5orf35 -0.54 -5.39 -0.44 3.45e-7 Coronary artery disease; TGCT cis rs644799 0.544 rs56298021 chr11:95545113 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.56 5.71 0.46 7.98e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs67311347 1.000 rs7612015 chr3:40399974 A/C cg17264618 chr3:40429014 ENTPD3 0.31 4.65 0.39 8.38e-6 Renal cell carcinoma; TGCT cis rs9486715 0.867 rs9373833 chr6:96904998 A/G cg18709589 chr6:96969512 KIAA0776 -0.77 -7.64 -0.57 4.99e-12 Headache; TGCT cis rs4906332 0.570 rs7140558 chr14:104018651 A/G cg26031613 chr14:104095156 KLC1 -0.65 -5.19 -0.42 8.4e-7 Coronary artery disease; TGCT cis rs6951245 0.935 rs79067319 chr7:1065548 C/T cg18402987 chr7:1209562 NA 0.65 5.32 0.43 4.65e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8033133 0.602 rs12438531 chr15:25323876 A/C cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.24 -4.82 -0.4 4.2e-6 Blood osmolality (transformed sodium); TGCT cis rs1552244 0.935 rs7649243 chr3:10089470 T/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs5769707 0.681 rs4622843 chr22:50036916 T/G cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 5e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs45509595 0.841 rs200485 chr6:27775697 G/C cg08798685 chr6:27730294 NA -0.33 -4.53 -0.38 1.34e-5 Breast cancer; TGCT cis rs6840360 0.642 rs1372977 chr4:152452398 G/A cg17479576 chr4:152424074 FAM160A1 -0.59 -6.29 -0.49 4.87e-9 Intelligence (multi-trait analysis); TGCT cis rs910316 0.737 rs175424 chr14:75626257 T/C cg08847533 chr14:75593920 NEK9 -0.83 -8.23 -0.59 2.13e-13 Height; TGCT trans rs2469997 0.925 rs2470032 chr8:120371299 A/G cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs10946940 0.930 rs10807029 chr6:27573463 G/A cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.73 -0.39 5.93e-6 Systemic lupus erythematosus; TGCT cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs2836974 0.897 rs13047678 chr21:40708853 C/T cg11644478 chr21:40555479 PSMG1 0.92 8.18 0.59 2.86e-13 Cognitive function; TGCT cis rs12908161 1.000 rs12912388 chr15:85344550 T/A cg11189052 chr15:85197271 WDR73 0.71 5.87 0.47 3.68e-8 Schizophrenia; TGCT cis rs1953600 0.818 rs2152546 chr10:81906384 G/T cg04850286 chr10:81895943 PLAC9 -0.4 -4.91 -0.4 2.85e-6 Sarcoidosis; TGCT cis rs2070488 0.965 rs2051215 chr3:38560345 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.82 -8.21 -0.59 2.46e-13 Electrocardiographic conduction measures; TGCT cis rs669446 0.562 rs304303 chr1:44178070 T/G cg12908607 chr1:44402522 ARTN -0.55 -5.73 -0.46 7.35e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs6964587 0.839 rs12536702 chr7:91471576 G/C cg17063962 chr7:91808500 NA 0.82 8.48 0.61 5.69e-14 Breast cancer; TGCT cis rs210138 0.832 rs375555 chr6:33557741 T/C cg24505687 chr6:33548425 BAK1 0.46 4.87 0.4 3.38e-6 Testicular germ cell tumor; TGCT cis rs6669384 0.774 rs4844621 chr1:208030303 A/G cg22525895 chr1:207977042 MIR29B2 -0.44 -6.65 -0.51 8.33e-10 Immune response to measles vaccine (measles-specific neutralising antibody titre); TGCT cis rs7607369 0.680 rs533760 chr2:219381405 T/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs11690462 0.963 rs7603413 chr2:26561117 C/A cg04726446 chr2:26624865 C2orf39 0.44 4.72 0.39 6.34e-6 Coronary artery disease; TGCT cis rs4149423 1.000 rs4149420 chr2:108913090 G/T cg25838818 chr2:108905173 SULT1C2 -0.42 -6.91 -0.53 2.22e-10 Lobe size; TGCT cis rs35883536 0.647 rs2809790 chr1:101040461 C/T cg10298815 chr1:101004474 GPR88 0.24 4.51 0.38 1.47e-5 Monocyte count; TGCT cis rs7666738 0.830 rs7659420 chr4:98878714 G/C cg05340658 chr4:99064831 C4orf37 0.54 6.13 0.48 1.06e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs561341 0.700 rs6505266 chr17:30225813 G/A cg13647721 chr17:30228624 UTP6 0.6 5.32 0.43 4.72e-7 Hip circumference adjusted for BMI; TGCT cis rs6484504 0.600 rs208063 chr11:31159777 C/T cg26647111 chr11:31128758 NA -0.33 -4.62 -0.38 9.66e-6 Red blood cell count; TGCT cis rs916888 0.773 rs199534 chr17:44824213 T/G cg15921436 chr17:44337874 NA 0.56 7.75 0.57 2.88e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12477438 0.539 rs720228 chr2:99704547 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.81 0.75 1.89e-24 Chronic sinus infection; TGCT cis rs2204008 0.685 rs4556621 chr12:38187236 C/A cg26384229 chr12:38710491 ALG10B 0.85 7.48 0.56 1.21e-11 Bladder cancer; TGCT cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg12756686 chr19:29218302 NA 0.77 6.61 0.51 1.01e-9 Methadone dose in opioid dependence; TGCT cis rs11118844 0.843 rs11118847 chr1:221922614 A/G cg04222084 chr1:221915650 DUSP10 -0.78 -5.42 -0.44 2.99e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs2019137 0.539 rs6755040 chr2:113981137 T/C cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.38 5.06 0.41 1.47e-6 Lymphocyte counts; TGCT cis rs7666738 0.716 rs6814353 chr4:99074202 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.16 0.54 6.13e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2288884 0.943 rs11671792 chr19:52581683 A/T cg15405931 chr19:52693188 PPP2R1A -0.7 -4.57 -0.38 1.16e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs9611565 0.504 rs5758452 chr22:42144927 G/A cg13695892 chr22:41940480 POLR3H 0.8 7.65 0.57 4.87e-12 Vitiligo; TGCT cis rs6840360 0.901 rs1561915 chr4:152479724 G/A cg17479576 chr4:152424074 FAM160A1 -0.54 -6.09 -0.48 1.31e-8 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.904 rs55866125 chr17:28312993 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 7.92 0.58 1.17e-12 Coffee consumption (cups per day); TGCT cis rs2594989 0.895 rs2442789 chr3:11540188 C/T cg00170343 chr3:11313890 ATG7 0.64 4.74 0.39 5.78e-6 Circulating chemerin levels; TGCT cis rs35146811 0.735 rs1637001 chr7:99808151 G/A cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs950027 0.787 rs1547487 chr15:45723983 A/G cg26924012 chr15:45694286 SPATA5L1 0.66 7.08 0.54 9.38e-11 Response to fenofibrate (adiponectin levels); TGCT cis rs7586879 0.964 rs13412941 chr2:25102709 C/T cg01884057 chr2:25150051 NA 0.26 4.58 0.38 1.13e-5 Body mass index; TGCT cis rs317689 0.702 rs544696 chr12:69749939 T/C cg20891283 chr12:69753455 YEATS4 0.67 5.88 0.47 3.62e-8 Response to diuretic therapy; TGCT trans rs1814175 0.817 rs10839401 chr11:49876144 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs617219 0.671 rs2220839 chr5:78603510 T/A cg23987322 chr5:78407566 BHMT -0.35 -4.75 -0.39 5.49e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7760949 0.963 rs9349840 chr6:13903809 G/A cg27413430 chr6:13925136 RNF182 0.51 4.78 0.39 4.79e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs8072100 0.701 rs8075566 chr17:45771037 G/A cg08085267 chr17:45401833 C17orf57 -0.43 -4.82 -0.4 4.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7914558 0.966 rs4917997 chr10:104945213 A/G cg04362960 chr10:104952993 NT5C2 0.61 5.47 0.44 2.42e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs709400 0.526 rs11622835 chr14:103967504 G/A cg12935359 chr14:103987150 CKB -0.48 -6.32 -0.49 4.2e-9 Body mass index; TGCT cis rs9325144 0.723 rs3887436 chr12:39189526 A/C cg10518543 chr12:38710700 ALG10B -0.5 -4.65 -0.39 8.28e-6 Morning vs. evening chronotype; TGCT cis rs7584330 0.554 rs79213383 chr2:238426890 A/G cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs2404602 0.692 rs57178708 chr15:76904069 T/C cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.08e-6 Blood metabolite levels; TGCT cis rs9660180 0.620 rs34298494 chr1:1663402 A/C cg13866156 chr1:1669148 SLC35E2 0.24 5.5 0.44 2.03e-7 Body mass index; TGCT cis rs6087990 0.735 rs4911261 chr20:31391360 A/G cg13636640 chr20:31349939 DNMT3B 0.95 12.3 0.74 3.25e-23 Ulcerative colitis; TGCT cis rs7100689 0.646 rs1047952 chr10:82126808 C/G cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs1153858 1.000 rs1554521 chr15:45664189 A/T cg26924012 chr15:45694286 SPATA5L1 -1.1 -14.88 -0.8 2.26e-29 Homoarginine levels; TGCT cis rs11640734 0.619 rs2293586 chr16:89962394 A/G cg06558623 chr16:89946397 TCF25 0.41 4.82 0.4 4.15e-6 Interleukin-17 levels; TGCT cis rs11247915 0.583 rs66569416 chr1:26659737 C/G cg23732845 chr1:26663426 AIM1L -0.34 -4.44 -0.37 1.95e-5 Obesity-related traits; TGCT cis rs2278034 0.578 rs881753 chr3:195606770 C/T cg01181863 chr3:195395398 SDHAP2 0.36 5.12 0.42 1.11e-6 Bronchopulmonary dysplasia; TGCT cis rs2836950 0.501 rs2836980 chr21:40687618 G/T cg11890956 chr21:40555474 PSMG1 -0.66 -6.24 -0.49 6.47e-9 Menarche (age at onset); TGCT cis rs9486715 0.867 rs12207471 chr6:96963782 A/G cg18709589 chr6:96969512 KIAA0776 0.82 8.01 0.58 7.14e-13 Headache; TGCT cis rs1552244 0.882 rs67762674 chr3:10014485 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 5.93 0.47 2.76e-8 Alzheimer's disease; TGCT cis rs9486715 0.838 rs9486275 chr6:96901187 C/T cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg04944784 chr2:26401820 FAM59B 0.77 6.37 0.5 3.27e-9 Gut microbiome composition (summer); TGCT cis rs7552404 1.000 rs7548962 chr1:76139266 G/A cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4767364 0.848 rs10774649 chr12:112539516 A/G cg10833066 chr12:111807467 FAM109A 0.34 5.22 0.42 7.39e-7 Oral cavity and pharyngeal cancer; TGCT cis rs478304 0.651 rs11227279 chr11:65495211 G/A cg17480646 chr11:65405466 SIPA1 -0.57 -6.92 -0.53 2.1e-10 Acne (severe); TGCT cis rs4665809 0.590 rs35532350 chr2:26441605 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs7086627 0.515 rs11202957 chr10:82209592 A/G cg01528321 chr10:82214614 TSPAN14 0.65 6.21 0.49 7.21e-9 Post bronchodilator FEV1; TGCT cis rs7312933 0.645 rs12049942 chr12:42587052 G/A cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs1483890 0.723 rs6549207 chr3:69412018 T/G cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs9921192 0.872 rs12930815 chr16:4348635 C/T cg00021532 chr16:4324280 TFAP4 0.83 9.35 0.64 4.71e-16 Prostate-specific antigen levels; TGCT cis rs12477438 0.501 rs6753063 chr2:99801469 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs7666738 0.791 rs11729596 chr4:99045461 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2147959 0.630 rs10753449 chr1:228672526 A/G cg22700015 chr1:228743131 NA -0.61 -4.7 -0.39 6.82e-6 Adult asthma; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.56 5.0 0.41 1.91e-6 Prudent dietary pattern; TGCT cis rs12497850 0.931 rs13315711 chr3:48986399 A/T cg07636037 chr3:49044803 WDR6 0.96 10.39 0.68 1.45e-18 Parkinson's disease; TGCT cis rs2637266 0.818 rs7894799 chr10:78392012 T/C cg18941641 chr10:78392320 NA 0.43 5.58 0.45 1.46e-7 Pulmonary function; TGCT cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs7216064 1.000 rs6504543 chr17:65837659 T/C cg12091567 chr17:66097778 LOC651250 -0.84 -6.8 -0.52 4.01e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7246657 0.722 rs4802051 chr19:38072328 C/A cg18154014 chr19:37997991 ZNF793 0.69 4.67 0.39 7.74e-6 Coronary artery calcification; TGCT cis rs12541335 0.603 rs9792127 chr8:22180334 G/A cg26039829 chr8:22132926 PIWIL2 0.27 5.07 0.41 1.39e-6 Hypertriglyceridemia; TGCT cis rs514406 0.929 rs1672908 chr1:53340885 A/G cg08736216 chr1:53307985 ZYG11A -0.29 -5.7 -0.46 8.08e-8 Monocyte count; TGCT cis rs1552244 0.572 rs6783705 chr3:10164783 A/G cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs826838 1.000 rs826888 chr12:39104719 C/G cg13010199 chr12:38710504 ALG10B -0.62 -5.03 -0.41 1.7e-6 Heart rate; TGCT cis rs478304 0.651 rs4930313 chr11:65500428 C/T cg10518572 chr11:65560635 OVOL1 -0.24 -4.68 -0.39 7.53e-6 Acne (severe); TGCT cis rs854765 0.647 rs854767 chr17:18018263 A/C cg04398451 chr17:18023971 MYO15A 0.38 6.63 0.51 9.43e-10 Total body bone mineral density; TGCT cis rs67072384 1.000 rs7125722 chr11:72449716 G/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs4689388 0.890 rs4481292 chr4:6298375 C/T cg00701064 chr4:6280414 WFS1 0.44 5.77 0.46 5.96e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg03806693 chr22:41940476 POLR3H 1.16 13.01 0.76 6.19e-25 Vitiligo; TGCT cis rs11690935 0.610 rs3770458 chr2:172651287 C/T cg13550731 chr2:172543902 DYNC1I2 0.69 6.04 0.48 1.69e-8 Schizophrenia; TGCT cis rs7824557 0.736 rs35392635 chr8:11164349 G/C cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs56399783 0.901 rs757788 chr7:2836433 A/G cg19731401 chr7:2775893 GNA12 0.35 4.73 0.39 5.94e-6 Childhood ear infection; TGCT cis rs7959452 0.590 rs7968629 chr12:69782857 G/A cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs4499344 0.556 rs259243 chr19:33144726 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.2 0.59 2.58e-13 Mean platelet volume; TGCT cis rs7208859 0.562 rs11650923 chr17:29008167 G/A cg13385521 chr17:29058706 SUZ12P 0.75 4.51 0.38 1.5e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs8051431 0.876 rs9927968 chr16:72021767 T/C cg06353428 chr16:71660113 MARVELD3 0.59 4.56 0.38 1.23e-5 LDL cholesterol levels; TGCT cis rs514406 0.861 rs35517489 chr1:53304062 G/C cg22166914 chr1:53195759 ZYG11B 0.4 6.66 0.51 8.01e-10 Monocyte count; TGCT cis rs12540874 0.522 rs4947641 chr7:50489038 C/T cg18232548 chr7:50535776 DDC -0.37 -6.42 -0.5 2.68e-9 Systemic sclerosis; TGCT cis rs6879260 1.000 rs7730585 chr5:179733440 T/C cg23221052 chr5:179740743 GFPT2 -0.36 -5.75 -0.46 6.7e-8 Height; TGCT cis rs77741769 0.571 rs3883901 chr12:121256520 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs4862750 0.872 rs7658314 chr4:187900356 T/C cg03452623 chr4:187889614 NA -0.34 -4.94 -0.41 2.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs75686122 0.892 rs17234011 chr8:104634925 A/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs10504229 0.683 rs35840293 chr8:58117634 C/T cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs6964587 0.740 rs2020360 chr7:91439506 G/C cg17063962 chr7:91808500 NA 0.82 8.45 0.6 6.54e-14 Breast cancer; TGCT cis rs2242116 0.743 rs11719795 chr3:46951935 T/C cg27129171 chr3:47204927 SETD2 0.58 5.46 0.44 2.5e-7 Birth weight; TGCT trans rs1814175 0.817 rs6486044 chr11:49982718 C/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs769267 0.895 rs1000237 chr19:19518316 T/A cg20644253 chr19:19431407 KIAA0892;SF4 0.62 5.25 0.43 6.3e-7 Tonsillectomy; TGCT cis rs2153535 0.580 rs2327062 chr6:8453858 G/A cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs4478858 0.775 rs12139418 chr1:31706352 T/C cg00250761 chr1:31883323 NA -0.3 -5.52 -0.44 1.88e-7 Alcohol dependence; TGCT cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg03517284 chr6:25882590 NA -0.64 -5.76 -0.46 6.3e-8 Intelligence (multi-trait analysis); TGCT cis rs6088580 0.634 rs62212172 chr20:32987705 G/A cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs769267 1.000 rs12985655 chr19:19442434 G/A cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.11 -0.42 1.17e-6 Tonsillectomy; TGCT cis rs10206020 0.885 rs13411553 chr2:1574018 A/G cg12573674 chr2:1569213 NA -0.45 -5.12 -0.42 1.14e-6 IgG glycosylation; TGCT cis rs910316 1.000 rs10142626 chr14:75555636 A/T cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT cis rs2486288 0.656 rs7162022 chr15:45565253 C/T cg26924012 chr15:45694286 SPATA5L1 -0.72 -6.91 -0.53 2.3e-10 Glomerular filtration rate; TGCT cis rs2847281 0.761 rs641085 chr18:12824930 A/T cg23598886 chr18:12777645 NA 0.39 4.75 0.39 5.61e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs10931896 0.531 rs295117 chr2:201146828 C/T cg23649088 chr2:200775458 C2orf69 0.39 6.35 0.5 3.65e-9 Systolic blood pressure; TGCT cis rs4253772 0.514 rs11704878 chr22:46714664 C/T cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs2836974 0.644 rs7281853 chr21:40693490 A/G cg11644478 chr21:40555479 PSMG1 -0.52 -4.64 -0.38 8.56e-6 Cognitive function; TGCT cis rs3809566 0.559 rs4775605 chr15:63324048 C/G cg00520135 chr15:63333846 TPM1 -0.4 -5.0 -0.41 1.95e-6 Platelet count; TGCT cis rs394563 0.559 rs7752555 chr6:149671116 A/G cg16235748 chr6:149772707 ZC3H12D 0.44 5.06 0.41 1.47e-6 Dupuytren's disease; TGCT cis rs12039431 0.788 rs11749 chr1:38023316 C/T cg17933807 chr1:38061675 GNL2 -0.8 -7.8 -0.57 2.15e-12 Epithelial ovarian cancer; TGCT cis rs3733585 0.699 rs62294332 chr4:9959989 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg04317399 chr7:27170313 HOXA4 -0.44 -5.04 -0.41 1.64e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs3617 0.573 rs4687680 chr3:52907372 G/A cg10802521 chr3:52805072 NEK4 -0.54 -5.99 -0.47 2.09e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs6964587 1.000 rs10243241 chr7:91705696 A/G cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs4665809 0.590 rs13019536 chr2:26526978 C/A cg04944784 chr2:26401820 FAM59B -0.75 -5.38 -0.43 3.64e-7 Gut microbiome composition (summer); TGCT cis rs4478858 0.735 rs7556340 chr1:31788453 A/T cg00250761 chr1:31883323 NA -0.27 -4.82 -0.4 4.15e-6 Alcohol dependence; TGCT cis rs1153858 0.723 rs1719238 chr15:45594766 C/T cg14582100 chr15:45693742 SPATA5L1 -0.47 -5.08 -0.42 1.34e-6 Homoarginine levels; TGCT cis rs116095464 0.558 rs10057626 chr5:239720 T/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs6089584 1.000 rs6089584 chr20:60564086 G/C cg13770153 chr20:60521292 NA -0.44 -5.69 -0.46 8.52e-8 Body mass index; TGCT cis rs8063761 0.640 rs4785760 chr16:90051438 G/A cg08547343 chr16:90038815 CENPBD1;AFG3L1 0.68 6.63 0.51 9.15e-10 Squamous cell carcinoma; TGCT cis rs1008375 1.000 rs13119927 chr4:17691640 G/A cg18681998 chr4:17616180 MED28 -0.78 -7.29 -0.55 3.26e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs910316 1.000 rs12590452 chr14:75548756 T/C cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs6667605 0.527 rs12046118 chr1:2540343 A/C cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs10256972 0.567 rs2960835 chr7:1202963 A/G cg18402987 chr7:1209562 NA 0.37 4.58 0.38 1.1e-5 Longevity;Endometriosis; TGCT cis rs7954584 0.520 rs1169094 chr12:122465535 A/G cg22168489 chr12:122356033 WDR66 -0.19 -4.52 -0.38 1.42e-5 Mean corpuscular volume; TGCT cis rs2594989 0.943 rs2454499 chr3:11500531 T/C cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.58e-5 Circulating chemerin levels; TGCT cis rs66486766 1 rs66486766 chr15:84806060 G/A cg11189052 chr15:85197271 WDR73 0.78 6.39 0.5 3.08e-9 Bipolar disorder lithium response (categorical) or schizophrenia; TGCT cis rs4790312 0.513 rs12451211 chr17:1965542 A/G cg24156229 chr17:1948635 NA 0.34 5.99 0.47 2.09e-8 Left atrial antero-posterior diameter; TGCT cis rs11696845 0.626 rs6073537 chr20:43378270 A/G cg09357268 chr20:43379437 KCNK15 -0.24 -4.53 -0.38 1.36e-5 Obesity-related traits; TGCT cis rs11190604 1.000 rs12354411 chr10:102294537 G/A cg23241863 chr10:102295624 HIF1AN 0.67 5.12 0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28386778 0.897 rs6504187 chr17:61917099 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs4819052 0.851 rs28622522 chr21:46676599 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12908161 0.959 rs17598603 chr15:85200211 C/G cg11189052 chr15:85197271 WDR73 -0.73 -6.2 -0.49 7.8e-9 Schizophrenia; TGCT cis rs11098499 0.644 rs7693919 chr4:120540571 G/A cg09307838 chr4:120376055 NA 0.62 5.86 0.47 3.86e-8 Corneal astigmatism; TGCT cis rs4494114 0.967 rs9438980 chr1:39355371 A/G cg25970120 chr1:39325951 RRAGC -0.6 -6.25 -0.49 6.18e-9 Blood protein levels; TGCT cis rs2075371 1.000 rs2544221 chr7:133993014 G/C cg11752832 chr7:134001865 SLC35B4 0.71 6.38 0.5 3.21e-9 Mean platelet volume; TGCT cis rs3806843 1.000 rs10050455 chr5:140204650 A/G cg19875535 chr5:140030758 IK 0.37 6.16 0.48 9.55e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9399135 0.967 rs9376077 chr6:135299713 C/G cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.33e-6 Red blood cell count; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg11905131 chr22:24372483 LOC391322 -0.95 -11.07 -0.7 3.16e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1218582 0.682 rs12046459 chr1:154912017 A/C cg09359103 chr1:154839909 KCNN3 -0.66 -12.3 -0.74 3.3e-23 Prostate cancer; TGCT cis rs7568458 0.846 rs6743030 chr2:85763520 C/T cg02493740 chr2:85810744 VAMP5 -0.27 -4.97 -0.41 2.2e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs3008870 1.000 rs2985797 chr1:67431499 C/T cg08660285 chr1:67390436 MIER1;WDR78 -1.12 -11.45 -0.72 3.77e-21 Lymphocyte percentage of white cells; TGCT cis rs4889911 0.544 rs2650254 chr17:77833655 A/G cg00646381 chr17:77835854 NA 0.45 6.48 0.5 1.99e-9 Electroencephalogram traits; TGCT cis rs7926906 0.643 rs4320920 chr11:90530211 A/G cg26138821 chr11:89956704 CHORDC1 -0.47 -4.77 -0.39 5.18e-6 Intelligence (multi-trait analysis); TGCT cis rs7216064 1.000 rs2365764 chr17:65857714 G/A cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs17331151 0.505 rs35225119 chr3:52623465 A/T cg07884673 chr3:53033167 SFMBT1 0.78 5.72 0.46 7.67e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4253772 0.591 rs8135363 chr22:46651713 T/C cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs4383453 0.539 rs55762427 chr3:123098421 A/G cg04890266 chr3:123102914 ADCY5 -0.49 -8.3 -0.6 1.5e-13 Gestational age at birth (maternal effect); TGCT cis rs7727544 0.735 rs274557 chr5:131721204 T/C cg24060327 chr5:131705240 SLC22A5 0.58 6.45 0.5 2.23e-9 Blood metabolite levels; TGCT cis rs1629083 0.935 rs2368238 chr11:118091761 T/G cg16594165 chr11:118135105 MPZL2 -0.33 -4.7 -0.39 6.73e-6 Lung cancer; TGCT cis rs9300255 0.602 rs1051431 chr12:123645803 G/A cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs9611565 0.765 rs727563 chr22:41867377 C/T cg06634786 chr22:41940651 POLR3H 0.81 7.78 0.57 2.42e-12 Vitiligo; TGCT cis rs933688 0.938 rs6866923 chr5:90669352 A/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.99 9.32 0.64 5.44e-16 Smoking behavior; TGCT cis rs11191270 0.590 rs12569901 chr10:104025410 C/G cg15320455 chr10:103880129 LDB1 0.85 5.39 0.44 3.36e-7 Intelligence (multi-trait analysis); TGCT cis rs4900538 0.787 rs11704 chr14:102808655 C/G cg18135206 chr14:102964638 TECPR2 0.19 4.53 0.38 1.37e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7829975 0.684 rs546603 chr8:8595838 T/G cg15556689 chr8:8085844 FLJ10661 -0.64 -5.47 -0.44 2.39e-7 Mood instability; TGCT cis rs57221529 0.825 rs72703051 chr5:582997 G/A cg09021430 chr5:549028 NA -0.41 -5.24 -0.43 6.79e-7 Lung disease severity in cystic fibrosis; TGCT trans rs7618501 0.633 rs12496973 chr3:50002245 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.87 9.66 0.66 8.25e-17 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs13136930 chr4:98937933 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.17 0.42 8.93e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.506 rs1984839 chr22:41685937 G/C cg06634786 chr22:41940651 POLR3H -0.63 -5.7 -0.46 8.4e-8 Vitiligo; TGCT cis rs250677 0.687 rs2963485 chr5:148452043 A/G cg18129178 chr5:148520854 ABLIM3 0.43 6.16 0.48 9.37e-9 Breast cancer; TGCT cis rs950169 0.579 rs881983 chr15:84647308 C/T cg11189052 chr15:85197271 WDR73 0.63 4.9 0.4 2.94e-6 Schizophrenia; TGCT cis rs477895 0.713 rs11607165 chr11:63963947 T/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 6.47 0.5 2.06e-9 Mean platelet volume; TGCT cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg03806693 chr22:41940476 POLR3H -1.02 -11.5 -0.72 2.83e-21 Vitiligo; TGCT cis rs9790314 0.586 rs1811483 chr3:161130900 A/G cg03342759 chr3:160939853 NMD3 -0.55 -5.69 -0.45 8.73e-8 Morning vs. evening chronotype; TGCT cis rs853679 0.567 rs6905380 chr6:28374902 A/G cg18815343 chr6:28367644 ZSCAN12 -0.48 -4.45 -0.37 1.88e-5 Depression; TGCT cis rs6845621 0.901 rs4697202 chr4:18920624 A/G cg12196642 chr4:18937545 NA -0.25 -4.44 -0.37 1.97e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs6964587 1.000 rs7811873 chr7:91751120 G/A cg22709100 chr7:91322751 NA 0.29 4.69 0.39 6.98e-6 Breast cancer; TGCT cis rs617219 0.737 rs2166343 chr5:78484060 A/G cg09550809 chr5:78407562 BHMT 0.41 5.75 0.46 6.45e-8 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7943203 1.000 rs7943063 chr11:108336907 G/T cg04873221 chr11:107992290 ACAT1 -0.49 -4.63 -0.38 9.02e-6 Red blood cell count;Mean corpuscular volume; TGCT cis rs68170813 0.617 rs17486 chr7:107112890 C/T cg02696742 chr7:106810147 HBP1 -0.64 -4.84 -0.4 3.8e-6 Coronary artery disease; TGCT cis rs2730245 0.527 rs842702 chr7:158696814 C/T cg11984989 chr7:158649758 WDR60 1.01 7.85 0.58 1.65e-12 Height; TGCT cis rs7666738 0.830 rs11932887 chr4:99072965 C/G cg18180107 chr4:99064573 C4orf37 0.6 5.35 0.43 4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 0.684 rs11854850 chr15:76844571 C/T cg23625390 chr15:77176239 SCAPER -0.37 -4.64 -0.38 8.72e-6 Blood metabolite levels; TGCT cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg04944784 chr2:26401820 FAM59B 0.75 6.09 0.48 1.29e-8 Gut microbiome composition (summer); TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.5 -4.72 -0.39 6.33e-6 Prudent dietary pattern; TGCT cis rs11190604 1.000 rs2495741 chr10:102331795 A/G cg23241863 chr10:102295624 HIF1AN 0.69 5.12 0.42 1.15e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs554111 0.613 rs3816455 chr1:21191430 A/G cg01072550 chr1:21505969 NA 0.34 5.22 0.42 7.27e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg01448562 chr3:133502909 NA -0.28 -5.27 -0.43 5.8e-7 Iron status biomarkers; TGCT cis rs17253792 0.822 rs10483650 chr14:56145312 A/G cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs16854884 0.586 rs4527375 chr3:143735515 A/T cg06585982 chr3:143692056 C3orf58 -0.56 -4.74 -0.39 5.87e-6 Economic and political preferences (feminism/equality); TGCT cis rs8077577 0.895 rs10048161 chr17:18082796 C/G cg09161412 chr17:18057145 MYO15A -0.66 -5.36 -0.43 3.94e-7 Obesity-related traits; TGCT cis rs13326165 0.760 rs67834575 chr3:52411929 T/A cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7666738 0.546 rs28444809 chr4:98916934 C/T cg05340658 chr4:99064831 C4orf37 0.6 6.62 0.51 9.9e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9611519 0.780 rs9611527 chr22:41644428 G/A cg13695892 chr22:41940480 POLR3H -0.65 -6.09 -0.48 1.3e-8 Neuroticism; TGCT cis rs986417 0.892 rs55695351 chr14:60796565 G/T cg27398547 chr14:60952738 C14orf39 -1.56 -6.75 -0.52 5.13e-10 Gut microbiota (bacterial taxa); TGCT cis rs2243480 1.000 rs1723267 chr7:65473314 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7917772 0.582 rs10748826 chr10:104354804 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4824093 0.610 rs2208023 chr22:50249983 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.47 4.86 0.4 3.55e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2070488 0.965 rs9829192 chr3:38569463 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.83 -8.45 -0.6 6.78e-14 Electrocardiographic conduction measures; TGCT cis rs7523273 0.606 rs2724398 chr1:207993699 A/G cg22525895 chr1:207977042 MIR29B2 -0.52 -8.85 -0.62 7.34e-15 Schizophrenia; TGCT cis rs1215050 0.765 rs644839 chr4:98716357 C/A cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs10435719 0.805 rs13269417 chr8:11791962 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs72899043 0.800 rs1942032 chr18:35337574 C/T cg10209886 chr18:34833563 BRUNOL4 0.46 4.72 0.39 6.38e-6 Neuroticism; TGCT cis rs72945132 0.882 rs7940090 chr11:70227824 C/G cg00319359 chr11:70116639 PPFIA1 1.03 7.86 0.58 1.59e-12 Coronary artery disease; TGCT cis rs66573146 0.901 rs55882710 chr4:7030704 G/A cg01220768 chr4:7056774 TADA2B 0.39 4.89 0.4 3.05e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7572733 0.555 rs700671 chr2:198690001 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs986417 1.000 rs10136642 chr14:60946098 G/C cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs909674 0.865 rs5757683 chr22:39850174 G/A cg01416388 chr22:39784598 NA -0.68 -6.21 -0.49 7.5e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4746818 0.579 rs79229724 chr10:70953872 C/T cg11621586 chr10:70884670 VPS26A -1.23 -5.0 -0.41 1.94e-6 Left atrial antero-posterior diameter; TGCT cis rs7208859 0.573 rs7223803 chr17:29077193 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2070488 0.775 rs13072731 chr3:38533335 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.76 7.39 0.55 1.93e-11 Electrocardiographic conduction measures; TGCT cis rs1552244 1.000 rs56394721 chr3:10150795 A/G cg00149659 chr3:10157352 C3orf10 0.95 6.09 0.48 1.32e-8 Alzheimer's disease; TGCT cis rs1799949 0.930 rs3765640 chr17:41276247 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs6693567 0.565 rs7544900 chr1:150262333 A/C cg09579323 chr1:150459698 TARS2 -0.53 -4.81 -0.4 4.38e-6 Migraine; TGCT cis rs6840360 0.571 rs6833814 chr4:152539679 A/G cg17479576 chr4:152424074 FAM160A1 -0.71 -7.72 -0.57 3.41e-12 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.966 rs2261794 chr20:25263062 T/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs72700829 0.593 rs77209899 chr1:150992019 G/A cg00666978 chr1:150947442 LASS2 0.9 4.62 0.38 9.37e-6 Schizophrenia; TGCT cis rs7567389 0.785 rs4150474 chr2:128033327 C/A cg09760422 chr2:128146352 NA -0.34 -4.46 -0.37 1.81e-5 Self-rated health; TGCT cis rs6933660 0.646 rs3816778 chr6:151773353 G/C cg14262678 chr6:151773367 RMND1;C6orf211 0.54 5.28 0.43 5.5e-7 Menarche (age at onset); TGCT cis rs478607 0.834 rs2666560 chr11:64480308 C/T cg19395706 chr11:64412079 NRXN2 -0.47 -5.02 -0.41 1.73e-6 Urate levels; TGCT cis rs2739330 0.892 rs4822455 chr22:24255296 C/T cg10819733 chr22:24237672 NA -0.3 -4.74 -0.39 5.76e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1670533 1.000 rs7679432 chr4:1050521 G/A cg27284194 chr4:1044797 NA 0.68 5.87 0.47 3.76e-8 Recombination rate (females); TGCT cis rs981844 1.000 rs2606328 chr4:154653864 C/T cg14289246 chr4:154710475 SFRP2 0.99 8.39 0.6 9.39e-14 Response to statins (LDL cholesterol change); TGCT cis rs10465746 0.967 rs28445286 chr1:84430483 A/G cg10977910 chr1:84465055 TTLL7 0.63 6.27 0.49 5.38e-9 Obesity-related traits; TGCT cis rs1541995 0.824 rs71396827 chr15:96243636 C/G cg00882281 chr15:96346592 NA 0.3 4.85 0.4 3.7e-6 Photic sneeze reflex; TGCT cis rs2658782 0.951 rs117384439 chr11:93111478 T/G cg18152523 chr11:93063302 CCDC67 0.67 5.33 0.43 4.44e-7 Pulmonary function decline; TGCT cis rs79349575 0.594 rs62078375 chr17:47034974 A/G cg26022315 chr17:47021804 SNF8 0.46 4.48 0.37 1.7e-5 Type 2 diabetes; TGCT trans rs12655019 0.920 rs16886497 chr5:56220714 T/C cg25190722 chr1:3801660 DFFB 0.67 7.44 0.56 1.48e-11 Breast cancer (early onset); TGCT cis rs7666738 0.606 rs4577589 chr4:99087858 A/G cg17366294 chr4:99064904 C4orf37 0.57 5.34 0.43 4.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10782582 0.593 rs77733234 chr1:76101655 A/T cg03433033 chr1:76189801 ACADM -0.61 -7.24 -0.55 4.07e-11 Daytime sleep phenotypes; TGCT cis rs422249 0.512 rs174576 chr11:61603510 C/A cg20584555 chr11:61717780 BEST1 -0.23 -4.47 -0.37 1.74e-5 Trans fatty acid levels; TGCT cis rs9473924 0.542 rs2857506 chr6:50800308 C/T cg14470998 chr6:50812995 TFAP2B 1.37 8.51 0.61 4.67e-14 Body mass index; TGCT cis rs12477438 0.765 rs17708262 chr2:99696313 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -5.07 -0.41 1.4e-6 Chronic sinus infection; TGCT cis rs7552404 0.691 rs61770550 chr1:76366966 C/T cg22875332 chr1:76189707 ACADM 0.7 6.84 0.52 3.26e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9915657 0.966 rs8071725 chr17:70128726 C/T cg06234051 chr17:70120541 SOX9 -0.28 -5.54 -0.45 1.72e-7 Thyroid hormone levels; TGCT cis rs9372498 0.505 rs62424204 chr6:118861642 G/A cg07617317 chr6:118971624 C6orf204 0.52 5.55 0.45 1.69e-7 Diastolic blood pressure; TGCT cis rs926938 0.527 rs58658580 chr1:115539726 A/G cg12756093 chr1:115239321 AMPD1 0.34 5.02 0.41 1.74e-6 Autism; TGCT cis rs174551 1 rs174551 chr11:61573684 T/C cg19610905 chr11:61596333 FADS2 -1.07 -12.03 -0.73 1.43e-22 LDL cholesterol; TGCT cis rs4733781 0.509 rs1158570 chr8:131331073 C/T cg16277922 chr8:131349729 ASAP1 -0.51 -8.42 -0.6 7.66e-14 Tuberculosis; TGCT cis rs11098499 0.954 rs11729521 chr4:120416788 T/C cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg25767906 chr1:53392781 SCP2 -0.51 -6.22 -0.49 6.83e-9 Monocyte count; TGCT cis rs4460629 0.742 rs7368345 chr1:155080090 C/T cg23973274 chr1:155060172 NA 0.24 4.65 0.39 8.33e-6 Serum magnesium levels; TGCT cis rs4951018 0.821 rs7529037 chr1:205637501 C/G cg14893161 chr1:205819251 PM20D1 -0.37 -4.9 -0.4 2.99e-6 Prostate-specific antigen levels; TGCT cis rs11098499 0.604 rs12642411 chr4:120580525 T/C cg09307838 chr4:120376055 NA 0.65 6.25 0.49 5.95e-9 Corneal astigmatism; TGCT cis rs7567389 0.583 rs11683427 chr2:127956543 A/G cg09760422 chr2:128146352 NA 0.36 4.58 0.38 1.1e-5 Self-rated health; TGCT cis rs13064411 0.735 rs6778800 chr3:113149236 A/G cg10517650 chr3:113235015 CCDC52 -0.35 -4.69 -0.39 7.18e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs10832963 1.000 rs10832956 chr11:18645668 A/G cg09201001 chr11:18656081 SPTY2D1 1.01 11.4 0.72 4.91e-21 Breast cancer; TGCT cis rs1865760 0.929 rs1436307 chr6:25939723 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.66 6.2 0.49 7.8e-9 Height; TGCT cis rs459571 0.959 rs2520099 chr9:136918139 T/C cg14405625 chr9:136855902 VAV2 -0.31 -4.53 -0.38 1.36e-5 Platelet distribution width; TGCT cis rs2760061 0.624 rs10442629 chr1:228191070 T/A cg02753203 chr1:228287806 NA 0.38 7.31 0.55 2.94e-11 Diastolic blood pressure; TGCT cis rs7178572 0.568 rs12913233 chr15:77543297 C/T cg22256960 chr15:77711686 NA -0.86 -8.69 -0.62 1.77e-14 Type 2 diabetes; TGCT cis rs3027234 0.727 rs74659626 chr17:8199143 G/A cg08322244 chr17:8066669 VAMP2 -0.56 -5.22 -0.42 7.34e-7 Telomere length; TGCT cis rs7264396 0.747 rs6058291 chr20:34247769 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.25 -0.43 6.33e-7 Total cholesterol levels; TGCT cis rs5769707 0.967 rs2071904 chr22:50034477 C/T cg05373962 chr22:49881684 NA -0.31 -6.42 -0.5 2.6e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs13118159 0.550 rs4974612 chr4:1364543 A/G cg05025164 chr4:1340916 KIAA1530 0.8 6.98 0.53 1.62e-10 Longevity; TGCT cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs425277 0.561 rs11584491 chr1:2042543 A/G cg24578937 chr1:2090814 PRKCZ -0.24 -5.62 -0.45 1.19e-7 Height; TGCT cis rs7829975 0.623 rs10092965 chr8:8373485 A/G cg06636001 chr8:8085503 FLJ10661 0.81 7.9 0.58 1.27e-12 Mood instability; TGCT cis rs208520 0.690 rs1563929 chr6:66702108 G/A cg07460842 chr6:66804631 NA 0.96 10.29 0.68 2.52e-18 Exhaled nitric oxide output; TGCT cis rs922182 0.617 rs28737203 chr15:64241169 C/T cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.33e-10 Blood protein levels; TGCT cis rs9467773 1.000 rs6925703 chr6:26521589 G/A cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.875 rs7767660 chr6:146436550 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.01 0.41 1.86e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7954584 0.567 rs11043246 chr12:122368944 G/A cg22168489 chr12:122356033 WDR66 0.22 4.76 0.39 5.27e-6 Mean corpuscular volume; TGCT cis rs12971120 0.891 rs4891557 chr18:72170299 C/T cg25817165 chr18:72167213 CNDP2 -0.29 -5.11 -0.42 1.16e-6 Refractive error; TGCT cis rs4819052 0.851 rs10470246 chr21:46659017 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.62 5.22 0.42 7.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs236907 0.859 rs10489252 chr1:171748145 A/T cg20598894 chr1:171756153 METTL13 -0.19 -4.47 -0.37 1.72e-5 Mean platelet volume; TGCT cis rs425277 0.917 rs12410859 chr1:2038732 C/T cg24578937 chr1:2090814 PRKCZ 0.29 6.55 0.51 1.38e-9 Height; TGCT cis rs1801251 1.000 rs9653383 chr2:233670380 A/C cg25237894 chr2:233734115 C2orf82 -0.33 -5.95 -0.47 2.53e-8 Coronary artery disease; TGCT cis rs2404602 0.716 rs12437627 chr15:76845050 T/C cg26408565 chr15:76604113 ETFA -0.4 -5.23 -0.43 6.98e-7 Blood metabolite levels; TGCT cis rs7246657 0.679 rs12461113 chr19:38083188 G/A cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs854765 0.647 rs7211714 chr17:17986955 A/G cg04398451 chr17:18023971 MYO15A -0.36 -6.31 -0.49 4.49e-9 Total body bone mineral density; TGCT cis rs644799 0.965 rs10831426 chr11:95505888 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.9 10.82 0.7 1.31e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs35306767 0.715 rs17221456 chr10:1037234 T/C cg18964960 chr10:1102726 WDR37 0.78 5.45 0.44 2.58e-7 Eosinophil percentage of granulocytes; TGCT cis rs6424115 0.657 rs519202 chr1:24045820 C/T cg15997130 chr1:24165203 NA 0.69 6.17 0.48 8.77e-9 Immature fraction of reticulocytes; TGCT cis rs4665809 1.000 rs10182857 chr2:26344411 C/T cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs6089829 0.962 rs4997812 chr20:61663153 T/G cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg10802521 chr3:52805072 NEK4 -0.7 -8.55 -0.61 3.79e-14 Bipolar disorder; TGCT cis rs8017423 0.967 rs28424204 chr14:90705669 G/C cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT trans rs4650994 0.935 rs2811290 chr1:178572978 C/T cg05059571 chr16:84539110 KIAA1609 0.39 7.01 0.53 1.33e-10 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg12889195 chr2:113992843 PAX8;LOC440839;LOC654433 0.38 5.06 0.41 1.47e-6 Lymphocyte counts; TGCT cis rs1775715 0.707 rs2065443 chr10:32164236 C/G cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs9916302 0.706 rs57933226 chr17:37412829 C/T cg07936489 chr17:37558343 FBXL20 -0.88 -6.37 -0.5 3.43e-9 Glomerular filtration rate (creatinine); TGCT cis rs7647973 0.667 rs4241405 chr3:49642027 C/T cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs6977660 0.714 rs10249635 chr7:19787090 A/G cg07541023 chr7:19748670 TWISTNB 0.85 4.72 0.39 6.16e-6 Thyroid stimulating hormone; TGCT cis rs7618915 0.532 rs13060675 chr3:52674300 T/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs6500602 0.679 rs736685 chr16:4508606 T/C cg08645402 chr16:4508243 NA 0.17 4.72 0.39 6.27e-6 Schizophrenia; TGCT cis rs3091242 0.967 rs665372 chr1:25719235 A/C cg23205692 chr1:25664452 TMEM50A 0.5 5.18 0.42 8.85e-7 Erythrocyte sedimentation rate; TGCT cis rs10823500 0.545 rs7082562 chr10:71945684 A/G cg04118878 chr10:71993077 PPA1 0.48 4.84 0.4 3.84e-6 Blood protein levels; TGCT cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg06634786 chr22:41940651 POLR3H -0.85 -8.04 -0.59 6.2e-13 Vitiligo; TGCT cis rs875971 0.862 rs7783779 chr7:65796626 A/G cg11764359 chr7:65958608 NA -0.54 -4.96 -0.41 2.27e-6 Aortic root size; TGCT cis rs875971 0.790 rs10257911 chr7:65743770 A/G cg11764359 chr7:65958608 NA -0.55 -4.89 -0.4 3.11e-6 Aortic root size; TGCT cis rs916888 0.610 rs199444 chr17:44818276 T/C cg01570182 chr17:44337453 NA 0.83 7.93 0.58 1.09e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs854624 0.901 rs1734960 chr17:34336348 A/G cg02022384 chr17:34097390 MMP28 0.5 4.67 0.39 7.74e-6 Blood protein levels; TGCT cis rs4727443 0.866 rs2897075 chr7:99630342 C/T cg13334819 chr7:99746414 C7orf59 0.56 4.71 0.39 6.63e-6 Interstitial lung disease; TGCT trans rs2288327 0.557 rs60488846 chr2:179357842 C/T cg18634211 chr1:26737262 LIN28 0.91 6.86 0.52 2.86e-10 Atrial fibrillation; TGCT cis rs875971 0.638 rs3898855 chr7:66036398 G/C cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs1158570 0.814 rs7839523 chr8:131281826 G/T cg16277922 chr8:131349729 ASAP1 0.47 6.98 0.53 1.59e-10 Platelet count; TGCT cis rs57920188 0.585 rs12126679 chr1:4072921 C/T cg20703997 chr1:4087676 NA 0.47 5.8 0.46 5.14e-8 Interleukin-17 levels; TGCT cis rs9467773 0.620 rs2498351 chr6:26659642 C/T cg05738196 chr6:26577821 NA 0.88 10.63 0.69 3.68e-19 Intelligence (multi-trait analysis); TGCT cis rs514406 0.679 rs61768344 chr1:53229274 G/A cg16325326 chr1:53192061 ZYG11B -0.58 -6.44 -0.5 2.36e-9 Monocyte count; TGCT cis rs2204008 0.715 rs12368462 chr12:38336116 C/G cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs8064299 0.967 rs7420 chr17:72765215 A/G cg25054828 chr17:72772726 NAT9;TMEM104 -0.73 -7.51 -0.56 1.02e-11 Monocyte count; TGCT cis rs478304 0.593 rs2236682 chr11:65480090 G/T cg17480646 chr11:65405466 SIPA1 -0.59 -6.88 -0.53 2.63e-10 Acne (severe); TGCT cis rs6089829 0.925 rs13041507 chr20:61666180 T/C cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs7193541 0.662 rs8063458 chr16:74469121 G/T cg01733217 chr16:74700730 RFWD3 -0.71 -7.33 -0.55 2.58e-11 Multiple myeloma; TGCT cis rs6684514 1.000 rs12132794 chr1:156281020 C/G cg20302342 chr1:156215951 PAQR6 -0.35 -4.74 -0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10782582 0.609 rs76260657 chr1:76338017 C/T cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs12908161 1.000 rs17601029 chr15:85347709 A/G cg17173187 chr15:85201210 NMB 0.56 6.26 0.49 5.79e-9 Schizophrenia; TGCT cis rs739401 0.572 rs384490 chr11:3078885 A/C cg05729581 chr11:3078854 CARS -0.55 -5.02 -0.41 1.71e-6 Longevity; TGCT cis rs7208859 0.623 rs9896603 chr17:29078512 C/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7100689 0.784 rs7082705 chr10:82170856 C/T cg01528321 chr10:82214614 TSPAN14 -0.95 -9.99 -0.67 1.36e-17 Post bronchodilator FEV1; TGCT cis rs10504229 0.683 rs16921810 chr8:58106067 A/G cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs1971762 0.762 rs4759282 chr12:54072435 C/A cg22997177 chr12:54070527 ATP5G2 -0.34 -4.54 -0.38 1.32e-5 Height; TGCT cis rs12701220 0.894 rs8591 chr7:1036799 C/T cg27454412 chr7:1067447 C7orf50 -0.48 -4.61 -0.38 9.67e-6 Bronchopulmonary dysplasia; TGCT cis rs9650657 0.645 rs4841407 chr8:10516185 G/A cg27411982 chr8:10470053 RP1L1 -0.23 -4.93 -0.4 2.62e-6 Neuroticism; TGCT cis rs7582180 0.629 rs893416 chr2:100957443 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1862618 0.853 rs10461617 chr5:56104308 A/G cg18230493 chr5:56204884 C5orf35 -0.67 -5.88 -0.47 3.5e-8 Initial pursuit acceleration; TGCT cis rs9362426 0.708 rs4707365 chr6:88100912 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.43 4.81 0.4 4.34e-6 Depressive episodes in bipolar disorder; TGCT cis rs7647973 0.626 rs11720705 chr3:49753788 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs6074578 0.597 rs7353361 chr20:134400 G/A cg16931068 chr20:139680 DEFB127 0.27 4.49 0.37 1.59e-5 Hirschsprung disease; TGCT cis rs28595532 0.920 rs115673173 chr4:119755321 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7258465 0.965 rs2561043 chr19:18622683 A/T cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs763014 0.966 rs4984677 chr16:671682 A/G cg09263875 chr16:632152 PIGQ 0.31 6.88 0.53 2.58e-10 Height; TGCT cis rs739496 0.579 rs7133881 chr12:112378768 A/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs36051895 0.623 rs7027871 chr9:5236822 C/G cg02405213 chr9:5042618 JAK2 0.64 6.89 0.53 2.5e-10 Pediatric autoimmune diseases; TGCT cis rs4808199 0.895 rs2285628 chr19:19467996 T/A cg20644253 chr19:19431407 KIAA0892;SF4 0.71 5.56 0.45 1.59e-7 Nonalcoholic fatty liver disease; TGCT cis rs9467711 1.000 rs1883215 chr6:26314233 G/C cg26531700 chr6:26746687 NA -1.08 -5.74 -0.46 7.01e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs4747241 1.000 rs4746112 chr10:74042995 G/A cg09661010 chr10:73848153 SPOCK2 0.4 4.46 0.37 1.8e-5 Heschl's gyrus morphology; TGCT cis rs9322193 0.884 rs12528279 chr6:150072028 A/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs539096 0.602 rs2970610 chr1:44097530 T/C cg12908607 chr1:44402522 ARTN -0.42 -4.7 -0.39 6.81e-6 Intelligence (multi-trait analysis); TGCT cis rs11122272 0.735 rs2256908 chr1:231506557 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs2075371 0.611 rs62462979 chr7:134019379 G/T cg11752832 chr7:134001865 SLC35B4 0.63 5.22 0.42 7.24e-7 Mean platelet volume; TGCT cis rs3784262 0.607 rs4646576 chr15:58338998 A/T cg12031962 chr15:58353849 ALDH1A2 -0.54 -8.34 -0.6 1.2e-13 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6088580 0.634 rs4142007 chr20:32990050 G/T cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs597539 0.690 rs647661 chr11:68625875 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.83 7.34 0.55 2.49e-11 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9653442 0.545 rs11681966 chr2:100759457 A/C cg22139774 chr2:100720529 AFF3 0.38 5.96 0.47 2.43e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7647973 0.826 rs9834535 chr3:49378797 A/T cg05785598 chr3:49045655 WDR6 0.38 4.5 0.37 1.56e-5 Menarche (age at onset); TGCT cis rs9311474 0.607 rs4475032 chr3:52560021 C/T cg10802521 chr3:52805072 NEK4 -0.73 -8.95 -0.63 4.37e-15 Electroencephalogram traits; TGCT cis rs769267 0.930 rs6909 chr19:19619542 A/G cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs4665809 0.590 rs6749046 chr2:26429451 C/G cg22920501 chr2:26401640 FAM59B 0.8 6.34 0.5 3.8e-9 Gut microbiome composition (summer); TGCT cis rs7809950 0.953 rs28687365 chr7:107106712 A/C cg23024343 chr7:107201750 COG5 -0.33 -5.34 -0.43 4.25e-7 Coronary artery disease; TGCT cis rs12497850 0.897 rs9850134 chr3:48957147 A/G cg05785598 chr3:49045655 WDR6 0.36 4.75 0.39 5.46e-6 Parkinson's disease; TGCT cis rs7659604 0.643 rs6839054 chr4:122663628 C/T cg19748678 chr4:122722346 EXOSC9 0.59 5.13 0.42 1.07e-6 Type 2 diabetes; TGCT cis rs3859192 0.561 rs12451547 chr17:38181168 T/C cg17467752 chr17:38218738 THRA -0.52 -4.59 -0.38 1.09e-5 White blood cell count; TGCT cis rs4642101 0.765 rs9871991 chr3:12827525 C/A cg05775895 chr3:12838266 CAND2 0.79 9.0 0.63 3.36e-15 QRS complex (12-leadsum); TGCT cis rs367943 0.871 rs348938 chr5:112825032 C/A cg12552261 chr5:112820674 MCC -0.22 -4.7 -0.39 6.84e-6 Type 2 diabetes; TGCT cis rs3733585 0.699 rs13328050 chr4:9951120 G/T cg11266682 chr4:10021025 SLC2A9 -0.54 -7.05 -0.54 1.08e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9611565 0.592 rs1811113 chr22:42073134 C/T cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Vitiligo; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg20007245 chr22:24372913 LOC391322 -0.77 -8.37 -0.6 1.03e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13394619 0.655 rs7578132 chr2:11718858 C/T cg07314298 chr2:11723111 GREB1 -0.27 -4.56 -0.38 1.21e-5 Endometriosis; TGCT cis rs5769707 0.967 rs739241 chr22:50052921 G/A cg20744362 chr22:50050164 C22orf34 0.28 4.54 0.38 1.32e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs12541335 0.639 rs7003478 chr8:22201123 A/G cg02463440 chr8:22132932 PIWIL2 0.26 5.2 0.42 7.85e-7 Hypertriglyceridemia; TGCT cis rs7927771 0.800 rs35996350 chr11:47389223 A/G cg21462715 chr11:47870315 NUP160 0.58 4.74 0.39 5.68e-6 Subjective well-being; TGCT cis rs6912958 0.559 rs446851 chr6:88043640 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.47 6.33 0.49 4.08e-9 Monocyte percentage of white cells; TGCT cis rs7044106 0.500 rs56725168 chr9:123492576 T/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.69 7.99 0.58 8.05e-13 Hip circumference adjusted for BMI; TGCT cis rs4665809 1.000 rs750452 chr2:26324995 G/A cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs12421382 0.543 rs10890996 chr11:109328421 A/G cg27471124 chr11:109292789 C11orf87 -0.49 -6.22 -0.49 7.04e-9 Schizophrenia; TGCT cis rs6951245 0.935 rs79143504 chr7:1110212 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg07061783 chr6:25882402 NA -0.46 -4.9 -0.4 2.94e-6 Blood metabolite levels; TGCT cis rs2243480 1.000 rs4145008 chr7:65647511 T/G cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs1862618 0.671 rs2591961 chr5:56238597 A/G cg24531977 chr5:56204891 C5orf35 0.7 7.44 0.56 1.47e-11 Initial pursuit acceleration; TGCT cis rs2439831 0.764 rs2447193 chr15:43929733 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.61 0.51 1.03e-9 Lung cancer in ever smokers; TGCT cis rs9527 0.590 rs10883818 chr10:104759586 A/G cg04362960 chr10:104952993 NT5C2 0.68 5.7 0.46 8.14e-8 Arsenic metabolism; TGCT cis rs7582180 0.629 rs11678148 chr2:100966950 A/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs6681544 0.544 rs3790904 chr1:82382517 G/T cg04226724 chr1:82268649 LPHN2 0.47 4.95 0.41 2.33e-6 Metabolite levels (X-11787); TGCT cis rs9308731 0.563 rs6760053 chr2:111932997 C/G cg04202892 chr2:111875749 ACOXL 0.44 4.88 0.4 3.2e-6 Chronic lymphocytic leukemia; TGCT cis rs10751667 0.961 rs10902263 chr11:992691 A/C cg06064525 chr11:970664 AP2A2 0.27 5.4 0.44 3.34e-7 Alzheimer's disease (late onset); TGCT cis rs59107033 0.559 rs62262396 chr3:123105491 A/G cg04890266 chr3:123102914 ADCY5 -0.48 -7.84 -0.58 1.81e-12 Lymphocyte counts; TGCT cis rs1008375 1.000 rs2286771 chr4:17643848 G/A cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28595532 0.688 rs116053430 chr4:119731375 G/A cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs4663969 0.873 rs759174 chr2:234668245 A/C cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.45 -0.37 1.86e-5 Total bilirubin levels in HIV-1 infection; TGCT cis rs9611565 0.879 rs2235845 chr22:41729294 T/G cg17554472 chr22:41940697 POLR3H -0.39 -4.49 -0.37 1.58e-5 Vitiligo; TGCT cis rs916888 0.821 rs199506 chr17:44859031 A/G cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs644799 0.664 rs603625 chr11:95554283 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.64 0.61 2.36e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs10174077 0.874 rs6750342 chr2:152485754 A/G cg06191203 chr2:152266755 RIF1 -0.71 -6.76 -0.52 4.93e-10 Squamous cell lung carcinoma; TGCT cis rs12579753 0.830 rs12825476 chr12:82238350 G/A cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg00814883 chr7:100076585 TSC22D4 -0.91 -8.03 -0.58 6.36e-13 Platelet count; TGCT cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.85 0.4 3.68e-6 Bipolar disorder; TGCT cis rs904251 0.600 rs12211110 chr6:37466232 A/G cg01843034 chr6:37503916 NA -0.48 -5.99 -0.47 2.11e-8 Cognitive performance; TGCT cis rs4924935 0.887 rs2428380 chr17:18843089 C/A cg26378065 chr17:18585709 ZNF286B -0.56 -4.59 -0.38 1.05e-5 Pancreatic cancer; TGCT cis rs17376456 0.569 rs2045021 chr5:93224222 G/A cg21475434 chr5:93447410 FAM172A -0.69 -5.2 -0.42 7.83e-7 Diabetic retinopathy; TGCT trans rs1864729 0.688 rs2567768 chr8:98303151 G/A cg08679828 chr8:102218111 ZNF706 -1.06 -7.16 -0.54 6.21e-11 Estradiol plasma levels (breast cancer); TGCT cis rs12220898 0.749 rs11101075 chr10:50485110 G/T cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs9486719 1.000 rs3906199 chr6:97049899 C/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs10858047 0.883 rs6658815 chr1:115209050 T/C cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs9581857 0.547 rs9579095 chr13:28082555 C/T cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs9733 0.544 rs2867302 chr1:150653650 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg02725872 chr8:58115012 NA -0.4 -4.78 -0.39 4.78e-6 Developmental language disorder (linguistic errors); TGCT cis rs9912789 0.744 rs9893755 chr17:79187432 C/T cg14413466 chr17:79170920 AZI1 0.25 4.45 0.37 1.9e-5 Frontotemporal dementia; TGCT trans rs208520 1.000 rs12190773 chr6:66968194 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.88 8.21 0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs344364 0.511 rs2982453 chr16:1949520 G/A cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs4788570 0.697 rs11075904 chr16:71816899 G/A cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs9788721 0.836 rs2656065 chr15:78750549 G/A cg18825076 chr15:78729989 IREB2 -0.32 -5.12 -0.42 1.15e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs4499344 0.920 rs2868149 chr19:33086096 C/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.6 -0.51 1.07e-9 Mean platelet volume; TGCT cis rs9634489 0.502 rs1328048 chr13:97119528 A/G cg11411106 chr13:97107445 HS6ST3 0.27 4.72 0.39 6.26e-6 Body mass index; TGCT cis rs3809863 0.602 rs6504833 chr17:45396087 A/G cg25173405 chr17:45401733 C17orf57 -0.42 -4.6 -0.38 1.04e-5 Glaucoma (primary open-angle); TGCT cis rs1461503 0.900 rs7102462 chr11:122828767 C/G cg27398637 chr11:122830231 C11orf63 -0.41 -4.77 -0.39 5.14e-6 Menarche (age at onset); TGCT cis rs7829975 0.714 rs12544992 chr8:8661681 C/G cg08975724 chr8:8085496 FLJ10661 0.56 4.89 0.4 3.03e-6 Mood instability; TGCT cis rs1348850 0.558 rs4337505 chr2:178529714 A/T cg22681709 chr2:178499509 PDE11A -0.46 -5.89 -0.47 3.46e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs250677 0.522 rs10040598 chr5:148365720 C/A cg18129178 chr5:148520854 ABLIM3 0.36 4.69 0.39 7.23e-6 Breast cancer; TGCT cis rs10823500 0.523 rs12774848 chr10:71932436 T/C cg04118878 chr10:71993077 PPA1 0.6 5.11 0.42 1.21e-6 Blood protein levels; TGCT cis rs6969780 0.915 rs12666926 chr7:27189561 A/G cg04321618 chr7:27170880 HOXA4 -0.52 -4.5 -0.38 1.51e-5 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs7772486 0.875 rs2748482 chr6:146336532 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.56 -0.38 1.23e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs853679 0.546 rs200953 chr6:27837267 T/C cg01031101 chr6:28227091 NKAPL -0.49 -4.63 -0.38 9.05e-6 Depression; TGCT trans rs4332037 0.826 rs4721188 chr7:1953615 G/A cg10840412 chr1:235813424 GNG4 -1.02 -8.17 -0.59 3.04e-13 Bipolar disorder; TGCT cis rs28595532 0.920 rs56104443 chr4:119752052 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs9467711 0.606 rs2073529 chr6:26375159 C/T cg16898833 chr6:26189333 HIST1H4D -1.09 -5.27 -0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2239547 0.522 rs2336669 chr3:52994138 C/T cg10802521 chr3:52805072 NEK4 0.61 5.9 0.47 3.2e-8 Schizophrenia; TGCT trans rs1908814 0.516 rs10113062 chr8:11793249 A/G cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 Neuroticism; TGCT cis rs7607369 0.566 rs55658481 chr2:219284215 G/A cg02176678 chr2:219576539 TTLL4 -0.48 -6.1 -0.48 1.23e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs7666738 0.678 rs7670805 chr4:99008763 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.5 0.44 2.09e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6500602 0.727 rs11076836 chr16:4569331 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.97 0.47 2.35e-8 Schizophrenia; TGCT cis rs3784262 0.565 rs2899613 chr15:58347260 T/C cg12031962 chr15:58353849 ALDH1A2 -0.38 -5.57 -0.45 1.53e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs11098499 0.866 rs12374352 chr4:120281977 C/T cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs911555 0.755 rs8014013 chr14:103937372 A/G cg12935359 chr14:103987150 CKB 0.33 4.51 0.38 1.46e-5 Intelligence (multi-trait analysis); TGCT cis rs1903068 0.719 rs1350545 chr4:56004454 C/T cg09978860 chr4:56023921 NA 0.53 5.63 0.45 1.14e-7 Endometriosis; TGCT cis rs9814567 1.000 rs9869981 chr3:134248801 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9858542 0.953 rs11719996 chr3:49525958 T/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs17401966 0.894 rs61778406 chr1:10435816 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.45 -0.44 2.57e-7 Hepatocellular carcinoma; TGCT cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg02353165 chr6:42928485 GNMT 0.97 9.95 0.67 1.66e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs5750830 0.594 rs5757650 chr22:39778419 A/G cg24399712 chr22:39784796 NA -0.93 -11.33 -0.71 7.31e-21 Intelligence (multi-trait analysis); TGCT cis rs9814567 1.000 rs4309773 chr3:134277301 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -8.81 -0.62 9.26e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg11905131 chr22:24372483 LOC391322 -0.95 -11.07 -0.7 3.22e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs425277 1.000 rs196128 chr1:2078444 T/G cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs7824557 0.568 rs35747588 chr8:11206627 C/G cg21775007 chr8:11205619 TDH 0.73 7.01 0.53 1.32e-10 Retinal vascular caliber; TGCT cis rs10031466 0.935 rs902909 chr4:189021465 A/G cg04086012 chr4:189060900 TRIML1 0.2 4.48 0.37 1.7e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg27588902 chr6:42928151 GNMT -0.56 -6.8 -0.52 4.02e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1997103 1.000 rs10278894 chr7:55404748 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs6582630 0.537 rs10785436 chr12:38461040 G/C cg26384229 chr12:38710491 ALG10B 0.82 7.5 0.56 1.07e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs8072100 1.000 rs4375701 chr17:45712218 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.13 -0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs711245 0.573 rs3770796 chr2:36799515 T/C cg10546459 chr2:36825355 FEZ2 0.57 5.18 0.42 8.89e-7 Height; TGCT cis rs2836974 0.526 rs1888488 chr21:40686521 C/T cg11890956 chr21:40555474 PSMG1 -0.77 -7.01 -0.53 1.33e-10 Cognitive function; TGCT cis rs9443189 0.570 rs567903 chr6:76327851 C/T cg01950844 chr6:76311363 SENP6 1.01 6.06 0.48 1.54e-8 Prostate cancer; TGCT cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs736408 0.581 rs3617 chr3:52833805 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.55 5.14 0.42 1.06e-6 Bipolar disorder; TGCT cis rs1018836 0.886 rs4734246 chr8:91569028 A/C cg16814680 chr8:91681699 NA -0.9 -9.91 -0.66 2.06e-17 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7246657 0.606 rs2972439 chr19:38212581 T/C cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs7829975 0.688 rs13270194 chr8:8378102 T/C cg06636001 chr8:8085503 FLJ10661 0.76 7.26 0.55 3.71e-11 Mood instability; TGCT cis rs11031096 0.711 rs10835723 chr11:4207566 G/C cg18678763 chr11:4115507 RRM1 -0.45 -5.84 -0.46 4.31e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs910316 0.712 rs175074 chr14:75504454 G/A cg11812906 chr14:75593930 NEK9 -0.58 -5.52 -0.44 1.92e-7 Height; TGCT cis rs12762955 0.561 rs1904671 chr10:1014603 G/A cg18964960 chr10:1102726 WDR37 -0.65 -5.81 -0.46 4.9e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs7809950 0.773 rs2237668 chr7:107050209 A/G cg23024343 chr7:107201750 COG5 -0.48 -6.33 -0.49 4.11e-9 Coronary artery disease; TGCT cis rs2302045 1.000 rs113807377 chr2:242052354 T/C cg04553960 chr2:241721320 KIF1A -0.7 -4.68 -0.39 7.4e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs12049351 0.774 rs12140727 chr1:229626891 C/G cg12130225 chr1:229698885 NA -0.39 -4.59 -0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs11931598 0.513 rs3857170 chr4:7003366 A/T cg02503808 chr4:7069936 GRPEL1 0.52 4.79 0.4 4.64e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs939574 0.512 rs2276638 chr2:220145286 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.78 5.54 0.45 1.71e-7 Platelet distribution width; TGCT cis rs2963155 0.518 rs865482 chr5:142640317 C/A cg17617527 chr5:142782415 NR3C1 0.85 6.31 0.49 4.45e-9 Breast cancer; TGCT cis rs9611565 0.592 rs5751139 chr22:42099981 G/C cg13695892 chr22:41940480 POLR3H 0.88 8.63 0.61 2.45e-14 Vitiligo; TGCT cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg15659132 chr6:26577336 NA 0.84 10.91 0.7 7.83e-20 Intelligence (multi-trait analysis); TGCT cis rs2862064 0.929 rs2088917 chr5:156432215 A/G cg12943317 chr5:156479607 HAVCR1 -0.45 -5.77 -0.46 5.83e-8 Platelet count; TGCT cis rs8016982 0.674 rs1951615 chr14:81671762 G/A cg01989461 chr14:81687754 GTF2A1 0.81 8.45 0.6 6.73e-14 Schizophrenia; TGCT cis rs17221829 0.692 rs55823055 chr11:89388744 G/A cg02982614 chr11:89391479 FOLH1B -0.25 -4.46 -0.37 1.8e-5 Anxiety in major depressive disorder; TGCT cis rs4880487 0.505 rs883660 chr10:1206834 A/G cg03183215 chr10:1252341 ADARB2 -0.24 -4.73 -0.39 5.99e-6 Migraine; TGCT cis rs9549260 0.816 rs964901 chr13:41248698 C/T cg21288729 chr13:41239152 FOXO1 0.97 9.92 0.67 1.94e-17 Red blood cell count; TGCT cis rs7666738 0.962 rs11728816 chr4:98951767 C/T cg17366294 chr4:99064904 C4orf37 0.8 7.2 0.54 5.04e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 0.698 rs1053628 chr1:46827769 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs17473412 0.784 rs116765405 chr5:122702576 A/G cg15125798 chr5:122621645 NA -0.57 -4.83 -0.4 3.88e-6 Total body bone mineral density; TGCT cis rs597539 0.652 rs602364 chr11:68662167 C/T cg06028808 chr11:68637592 NA 0.51 6.62 0.51 9.55e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs56341938 0.656 rs1420472 chr3:168776326 A/C cg07302051 chr16:51671357 NA -0.36 -6.67 -0.51 7.7e-10 Lung function (FEV1/FVC); TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg16590910 chr6:42928470 GNMT -0.49 -4.55 -0.38 1.24e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs751728 0.717 rs3763258 chr6:33773744 A/G cg00334056 chr6:33755658 LEMD2 -0.27 -4.88 -0.4 3.13e-6 Crohn's disease; TGCT cis rs9435341 0.965 rs55924375 chr1:107566690 C/A cg09367891 chr1:107599246 PRMT6 0.62 5.4 0.44 3.22e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg07167872 chr1:205819463 PM20D1 0.59 7.3 0.55 3.02e-11 Menarche (age at onset); TGCT cis rs6867032 1.000 rs4413568 chr5:2016894 A/G cg26168224 chr5:2018326 NA 0.43 8.0 0.58 7.57e-13 Gut microbiome composition (winter); TGCT cis rs6088580 0.634 rs1890000 chr20:32968312 G/T cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs3806843 0.518 rs2569188 chr5:140008419 G/A cg19875535 chr5:140030758 IK -0.33 -5.26 -0.43 6.05e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs6952808 0.789 rs35729895 chr7:1885069 C/T cg22963979 chr7:1858916 MAD1L1 -0.32 -4.78 -0.39 4.9e-6 Bipolar disorder and schizophrenia; TGCT cis rs7267979 1.000 rs6037095 chr20:25335687 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2288884 1.000 rs17835749 chr19:52578695 C/G cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs651907 0.535 rs12631513 chr3:101517476 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs7666738 0.680 rs11097613 chr4:99079991 G/T cg18180107 chr4:99064573 C4orf37 0.58 5.15 0.42 9.95e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs16921914 0.565 rs286650 chr11:31230207 T/C cg14844989 chr11:31128820 NA -0.23 -4.51 -0.38 1.47e-5 Bone mineral density (spine); TGCT cis rs853679 0.546 rs200981 chr6:27833174 A/G cg01031101 chr6:28227091 NKAPL -0.49 -4.66 -0.39 8.09e-6 Depression; TGCT cis rs12950390 0.853 rs12450733 chr17:45855404 A/G cg24803719 chr17:45855879 NA -0.47 -4.72 -0.39 6.14e-6 IgG glycosylation; TGCT cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs11264213 0.901 rs581459 chr1:36375110 C/T cg07093915 chr1:36184400 C1orf216 0.68 4.56 0.38 1.21e-5 Schizophrenia; TGCT cis rs17108533 0.588 rs12880297 chr14:71300055 A/T cg23900759 chr14:71108106 TTC9 -1.13 -4.56 -0.38 1.19e-5 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs3087591 1.000 rs2040791 chr17:29627297 G/C cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.51 -0.56 1.01e-11 Hip circumference; TGCT cis rs76889437 0.701 rs12987764 chr2:48961338 A/T cg25061755 chr2:48808114 STON1-GTF2A1L;STON1 0.17 4.49 0.37 1.63e-5 Facial morphology (factor 19); TGCT cis rs7677751 0.767 rs890205 chr4:55063373 C/A cg17187183 chr4:55093834 PDGFRA 0.48 6.38 0.5 3.27e-9 Corneal astigmatism; TGCT cis rs950027 0.620 rs35861938 chr15:45637343 T/C cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs7267979 1.000 rs2258066 chr20:25271326 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg25703541 chr22:24373054 LOC391322 0.94 11.43 0.72 4.18e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9906944 0.707 rs3816272 chr17:47120467 A/G cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs4689592 0.583 rs6823154 chr4:7078145 C/T cg25660036 chr4:7070649 GRPEL1 -0.57 -4.96 -0.41 2.25e-6 Monocyte percentage of white cells; TGCT cis rs13118159 0.778 rs12650998 chr4:1338832 T/C cg13395646 chr4:1353034 KIAA1530 -0.39 -4.83 -0.4 4.01e-6 Longevity; TGCT cis rs13108904 0.557 rs1250097 chr4:1238338 C/T cg19318889 chr4:1322082 MAEA -0.2 -4.91 -0.4 2.8e-6 Obesity-related traits; TGCT cis rs7267979 1.000 rs6050562 chr20:25336186 C/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9357506 0.935 rs1867015 chr6:46321089 T/G cg21115430 chr6:46460003 NA -0.24 -4.76 -0.39 5.19e-6 Body mass index; TGCT cis rs1799949 1.000 rs33994002 chr17:41328818 T/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs6740731 0.518 rs12996668 chr2:145298273 T/C cg07679370 chr2:145795797 NA 0.28 5.4 0.44 3.34e-7 Coronary artery disease; TGCT cis rs7727544 0.594 rs10479000 chr5:131607402 T/C cg24060327 chr5:131705240 SLC22A5 -0.54 -5.26 -0.43 6.24e-7 Blood metabolite levels; TGCT cis rs7828089 0.561 rs13266541 chr8:22266135 G/A cg12081754 chr8:22256438 SLC39A14 0.31 4.49 0.37 1.59e-5 Verbal declarative memory; TGCT cis rs2964802 0.505 rs13164697 chr5:10831212 C/T cg14521931 chr5:10832172 NA -0.27 -4.59 -0.38 1.06e-5 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg08859206 chr1:53392774 SCP2 -0.41 -6.12 -0.48 1.11e-8 Monocyte count; TGCT cis rs3820928 1.000 rs6752707 chr2:227766822 C/G cg11843606 chr2:227700838 RHBDD1 -0.51 -4.49 -0.37 1.6e-5 Pulmonary function; TGCT cis rs2836974 0.897 rs34599551 chr21:40594898 C/A cg17971929 chr21:40555470 PSMG1 0.98 9.58 0.65 1.3e-16 Cognitive function; TGCT cis rs7727544 0.548 rs35696821 chr5:131508017 C/T cg24060327 chr5:131705240 SLC22A5 -0.45 -4.47 -0.37 1.73e-5 Blood metabolite levels; TGCT cis rs2832191 0.755 rs2832193 chr21:30493589 T/C cg08807101 chr21:30365312 RNF160 -0.63 -5.79 -0.46 5.53e-8 Dental caries; TGCT cis rs3733585 0.664 rs28602527 chr4:9958327 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13108904 0.875 rs3822017 chr4:1236312 C/T cg16405210 chr4:1374714 KIAA1530 -0.21 -4.51 -0.38 1.48e-5 Obesity-related traits; TGCT cis rs11122272 0.701 rs2749702 chr1:231523808 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs3806843 0.966 rs6891559 chr5:140145206 G/A cg19875535 chr5:140030758 IK 0.37 6.23 0.49 6.53e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9467603 1.000 rs6939997 chr6:25821224 C/T cg16898833 chr6:26189333 HIST1H4D 1.18 5.6 0.45 1.33e-7 Intelligence (multi-trait analysis); TGCT cis rs240764 0.578 rs9322216 chr6:101251720 A/C cg21058520 chr6:100914733 NA 0.35 4.54 0.38 1.33e-5 Neuroticism; TGCT cis rs1129187 0.755 rs9471986 chr6:42944127 A/G cg17345569 chr6:42928274 GNMT -0.48 -5.01 -0.41 1.87e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6582630 0.502 rs11504451 chr12:38425294 G/A cg26384229 chr12:38710491 ALG10B 0.85 7.59 0.56 6.74e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs523522 0.923 rs3916065 chr12:120934624 A/C cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs9527 0.571 rs7096249 chr10:104618524 G/A cg04362960 chr10:104952993 NT5C2 0.55 4.73 0.39 5.91e-6 Arsenic metabolism; TGCT cis rs7172809 0.573 rs55994208 chr15:77525296 C/T cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT cis rs7017914 0.905 rs3110247 chr8:71934887 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs67311347 1.000 rs9829800 chr3:40443927 T/C cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg08736216 chr1:53307985 ZYG11A -0.3 -5.94 -0.47 2.72e-8 Monocyte count; TGCT cis rs6032067 0.516 rs16989916 chr20:43899514 C/T cg16667508 chr20:43936853 MATN4;RBPJL -0.38 -5.96 -0.47 2.38e-8 Blood protein levels; TGCT cis rs9467773 0.967 rs6924865 chr6:26521353 A/G cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs981844 1.000 rs72731670 chr4:154662471 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs929596 0.793 rs2741046 chr2:234580249 T/C cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.29 -4.58 -0.38 1.11e-5 Total bilirubin levels in HIV-1 infection; TGCT cis rs4455778 0.501 rs10227306 chr7:49048026 A/G cg26309511 chr7:48887640 NA 0.51 6.66 0.51 7.85e-10 Lung cancer in never smokers; TGCT cis rs8180040 0.701 rs13066214 chr3:47033937 C/T cg27129171 chr3:47204927 SETD2 0.74 9.74 0.66 5.36e-17 Colorectal cancer; TGCT cis rs1552244 1.000 rs17032276 chr3:10076975 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs9910055 0.530 rs8072954 chr17:42294722 G/A cg19774624 chr17:42201019 HDAC5 -0.7 -7.47 -0.56 1.24e-11 Total body bone mineral density; TGCT cis rs6558174 0.802 rs6558170 chr8:22487388 C/G cg03733263 chr8:22462867 KIAA1967 0.6 4.8 0.4 4.41e-6 Breast cancer; TGCT cis rs60843830 1.000 rs57542652 chr2:228088 G/A cg00108164 chr2:264199 ACP1;SH3YL1 0.73 6.74 0.52 5.3e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs13177918 0.677 rs3797622 chr5:149827098 G/A cg14059543 chr5:149831962 NA -0.71 -9.3 -0.64 6.32e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7809950 1.000 rs2293658 chr7:107270567 C/T cg23024343 chr7:107201750 COG5 -0.36 -6.02 -0.48 1.83e-8 Coronary artery disease; TGCT cis rs2439831 0.850 rs16965120 chr15:44100342 T/G cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.27 0.49 5.48e-9 Lung cancer in ever smokers; TGCT cis rs1107366 0.593 rs12635766 chr3:125930021 T/C cg01346077 chr3:125931526 NA 0.4 6.52 0.51 1.62e-9 Metabolite levels; TGCT cis rs739496 0.615 rs668774 chr12:112169652 G/C cg10833066 chr12:111807467 FAM109A 0.35 5.18 0.42 8.83e-7 Platelet count; TGCT cis rs11030122 0.660 rs10835247 chr11:3910306 G/A cg18678763 chr11:4115507 RRM1 -0.35 -4.45 -0.37 1.85e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs4919669 0.668 rs4244354 chr10:104426177 G/A cg05855489 chr10:104503620 C10orf26 0.86 4.63 0.38 9.05e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs875971 1.000 rs2036264 chr7:65799904 G/A cg11764359 chr7:65958608 NA -0.61 -5.51 -0.44 1.96e-7 Aortic root size; TGCT cis rs4595586 0.545 rs12810822 chr12:39391807 T/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7647973 1.000 rs7619789 chr3:49476263 T/C cg05785598 chr3:49045655 WDR6 0.37 4.52 0.38 1.42e-5 Menarche (age at onset); TGCT cis rs9486719 1.000 rs13208422 chr6:96892119 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs13242816 1.000 rs13233553 chr7:116182232 C/G cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs4144743 0.941 rs7222617 chr17:45324080 G/T cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs933688 1.000 rs332531 chr5:90790451 G/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.07 10.06 0.67 9.13e-18 Smoking behavior; TGCT cis rs9796 0.870 rs12910027 chr15:41283817 A/T cg18705301 chr15:41695430 NDUFAF1 0.43 5.52 0.44 1.9e-7 Menopause (age at onset); TGCT cis rs4595586 0.545 rs12812750 chr12:39363258 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.45 0.37 1.92e-5 Morning vs. evening chronotype; TGCT cis rs7224685 0.569 rs67005107 chr17:3991943 A/G cg09580393 chr17:4869866 SPAG7 -0.37 -4.49 -0.37 1.62e-5 Type 2 diabetes; TGCT cis rs2243480 1.000 rs7795242 chr7:65390094 T/C cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs17253792 0.822 rs2274075 chr14:56096731 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7010267 0.596 rs13262276 chr8:120033918 A/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs782590 0.935 rs2627779 chr2:55892356 A/G cg18811423 chr2:55921094 PNPT1 0.63 6.36 0.5 3.48e-9 Metabolic syndrome; TGCT cis rs7267979 0.844 rs8184820 chr20:25250577 C/T cg14121845 chr20:25566513 NINL -0.49 -4.96 -0.41 2.24e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs896854 1.000 rs896854 chr8:95960511 T/C cg13393036 chr8:95962371 TP53INP1 -0.63 -8.66 -0.61 2.14e-14 Type 2 diabetes; TGCT cis rs61884328 0.733 rs61897855 chr11:47231040 C/T cg13308137 chr11:47528955 CUGBP1 0.38 4.56 0.38 1.23e-5 Total body bone mineral density (age over 60); TGCT cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg09323728 chr8:95962352 TP53INP1 -0.53 -6.88 -0.53 2.67e-10 Type 2 diabetes; TGCT cis rs17253792 0.822 rs77033617 chr14:56129746 T/A cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs910316 1.000 rs4903275 chr14:75512509 C/T cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.36e-19 Height; TGCT cis rs1008375 1.000 rs6811887 chr4:17640858 C/T cg10189774 chr4:17578691 LAP3 0.56 5.04 0.41 1.57e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12477438 0.700 rs12467679 chr2:99654449 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs12477438 0.798 rs4850894 chr2:99629396 A/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs6121246 0.567 rs6058187 chr20:30190923 T/C cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs290268 0.838 rs290987 chr9:93563267 T/A cg02608019 chr9:93564028 SYK 0.44 4.44 0.37 1.94e-5 Platelet count; TGCT cis rs7772486 0.846 rs1331636 chr6:146338826 T/C cg05347473 chr6:146136440 FBXO30 0.56 5.29 0.43 5.34e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2046867 0.908 rs2679208 chr3:72787440 G/A cg25664220 chr3:72788482 NA 0.53 6.81 0.52 3.8e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs28595532 0.668 rs58467651 chr4:119349011 T/G cg11846333 chr4:119757529 SEC24D 0.76 4.57 0.38 1.17e-5 Cannabis dependence symptom count; TGCT cis rs2072499 0.966 rs11587860 chr1:156156951 G/C cg25208724 chr1:156163844 SLC25A44 1.11 15.72 0.82 2.62e-31 Testicular germ cell tumor; TGCT cis rs6089829 0.962 rs57684920 chr20:61662639 G/A cg18188782 chr20:61659543 NA -0.44 -5.19 -0.42 8.51e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs644799 0.710 rs3017756 chr11:95537358 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.65 0.61 2.18e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9733 0.596 rs6681990 chr1:150695929 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs4273100 0.646 rs6587216 chr17:19224397 G/C cg03910582 chr17:19030146 GRAPL -0.46 -5.09 -0.42 1.31e-6 Schizophrenia; TGCT cis rs1218582 0.804 rs869506 chr1:154859581 A/C cg06221963 chr1:154839813 KCNN3 -0.76 -13.06 -0.76 4.81e-25 Prostate cancer; TGCT cis rs9916302 0.904 rs9892055 chr17:37510402 C/T cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs16867321 0.570 rs73025489 chr2:181548425 A/G cg12875548 chr2:181044332 NA -0.35 -4.53 -0.38 1.34e-5 Obesity; TGCT cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.764 rs9403733 chr6:145912311 A/C cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT trans rs2688482 0.557 rs2550236 chr3:195522321 A/G cg17952111 chr19:54960355 LENG8 0.84 6.99 0.53 1.53e-10 Lung disease severity in cystic fibrosis; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg20007245 chr22:24372913 LOC391322 -0.71 -7.07 -0.54 1.01e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs854765 0.893 rs712265 chr17:18008447 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.65 -6.31 -0.49 4.57e-9 Total body bone mineral density; TGCT cis rs908922 0.923 rs11205010 chr1:152457964 C/T cg20991723 chr1:152506922 NA 0.47 5.96 0.47 2.39e-8 Hair morphology; TGCT cis rs514406 0.525 rs269291 chr1:53189297 C/T cg24675658 chr1:53192096 ZYG11B -0.87 -10.96 -0.7 5.93e-20 Monocyte count; TGCT cis rs10986311 0.862 rs912353 chr9:127119356 A/C cg14243010 chr9:127117328 LOC100129034;PSMB7 0.2 4.75 0.39 5.64e-6 Vitiligo; TGCT cis rs3864277 0.510 rs31478 chr5:131423475 T/C cg24060327 chr5:131705240 SLC22A5 -0.43 -4.55 -0.38 1.25e-5 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs9581857 0.685 rs9319368 chr13:28042275 T/G cg22138327 chr13:27999177 GTF3A 0.72 4.6 0.38 1.03e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7772486 0.790 rs2253307 chr6:146196181 T/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.46 -0.37 1.83e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9393777 0.588 rs11967935 chr6:26560672 A/C cg05738196 chr6:26577821 NA -0.63 -4.49 -0.37 1.59e-5 Intelligence (multi-trait analysis); TGCT cis rs2282802 0.685 rs1347143 chr5:139669386 A/G cg01081189 chr5:139537190 NA -0.28 -5.04 -0.41 1.59e-6 Intelligence (multi-trait analysis); TGCT cis rs1525293 0.509 rs10257424 chr7:70502669 T/C cg21135135 chr7:70597687 WBSCR17 -0.61 -5.63 -0.45 1.17e-7 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs9910055 0.659 rs7212573 chr17:42254281 A/G cg13607699 chr17:42295918 UBTF 0.57 5.08 0.41 1.38e-6 Total body bone mineral density; TGCT cis rs2688608 0.967 rs9971040 chr10:75661162 G/C cg23231163 chr10:75533350 FUT11 -0.27 -4.74 -0.39 5.8e-6 Inflammatory bowel disease; TGCT cis rs11190604 1.000 rs3750629 chr10:102275727 A/G cg16342193 chr10:102329863 NA -0.41 -5.34 -0.43 4.33e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7020830 0.898 rs13284651 chr9:37222681 G/T cg14294708 chr9:37120828 ZCCHC7 -1.24 -14.09 -0.78 1.68e-27 Schizophrenia; TGCT cis rs11105298 0.891 rs4842653 chr12:89834113 C/T cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2243480 1.000 rs1392104 chr7:65759107 G/A cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs7584330 0.666 rs60671275 chr2:238374318 C/A cg14458575 chr2:238380390 NA 0.6 9.06 0.63 2.41e-15 Prostate cancer; TGCT cis rs9457247 0.967 rs402191 chr6:167405553 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs10504229 0.906 rs6990615 chr8:58182956 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs11997175 0.574 rs58858314 chr8:33658221 T/C ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs7659604 0.605 rs1396080 chr4:122740454 T/G cg19748678 chr4:122722346 EXOSC9 0.81 8.3 0.6 1.46e-13 Type 2 diabetes; TGCT cis rs12210905 1.000 rs5030958 chr6:27214257 G/C cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT cis rs1348850 0.872 rs4893825 chr2:178298687 A/G cg22681709 chr2:178499509 PDE11A -0.37 -4.79 -0.4 4.67e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2120019 1.000 rs35736167 chr15:75332002 T/G cg17294928 chr15:75287854 SCAMP5 -0.78 -6.12 -0.48 1.14e-8 Blood trace element (Zn levels); TGCT cis rs6665290 0.901 rs61834005 chr1:227202789 C/T cg10327440 chr1:227177885 CDC42BPA -0.93 -16.71 -0.83 1.49e-33 Myeloid white cell count; TGCT cis rs10504229 1.000 rs68076606 chr8:58191271 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4372836 0.602 rs11685682 chr2:29056801 T/A cg09522027 chr2:28974177 PPP1CB 0.65 6.59 0.51 1.12e-9 Body mass index; TGCT cis rs2933343 1.000 rs789237 chr3:128636961 A/C cg11901034 chr3:128598214 ACAD9 -0.58 -4.96 -0.41 2.31e-6 IgG glycosylation; TGCT cis rs4713118 0.911 rs9295746 chr6:27730064 T/C cg20933634 chr6:27740509 NA 0.34 4.75 0.39 5.58e-6 Parkinson's disease; TGCT cis rs9611565 0.879 rs5758311 chr22:41759375 G/T cg02107564 chr22:41488750 EP300 -0.54 -4.44 -0.37 1.95e-5 Vitiligo; TGCT cis rs17253792 0.822 rs10483645 chr14:56103766 G/T cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs7226408 0.857 rs11661504 chr18:34518724 A/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs8177253 0.898 rs8177258 chr3:133480387 C/A cg11941060 chr3:133502564 NA -0.29 -6.16 -0.48 9.45e-9 Iron status biomarkers; TGCT cis rs4845570 1.000 rs6659705 chr1:151769750 T/C cg07092448 chr1:151763213 TDRKH -1.16 -9.41 -0.65 3.38e-16 Coronary artery disease; TGCT cis rs6921919 0.583 rs16894021 chr6:28345026 C/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6918586 0.658 rs198837 chr6:26113398 A/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.7 6.65 0.51 8.44e-10 Schizophrenia; TGCT cis rs10504229 0.773 rs60466370 chr8:58171248 A/C cg24829409 chr8:58192753 C8orf71 -0.51 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs908922 0.651 rs1885531 chr1:152480233 T/G cg20991723 chr1:152506922 NA 0.48 6.55 0.51 1.39e-9 Hair morphology; TGCT cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs2204008 0.869 rs34438288 chr12:38211582 G/T cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT trans rs7819412 0.538 rs4523214 chr8:10970773 T/A cg06636001 chr8:8085503 FLJ10661 -0.74 -6.84 -0.52 3.17e-10 Triglycerides; TGCT cis rs2228479 0.702 rs12599561 chr16:89894358 C/G cg06558623 chr16:89946397 TCF25 0.55 4.79 0.4 4.69e-6 Skin colour saturation; TGCT cis rs12615966 0.790 rs72830459 chr2:105387628 T/G cg16465502 chr2:105461796 NA 0.78 4.98 0.41 2.11e-6 Pancreatic cancer; TGCT trans rs1814175 0.817 rs7947526 chr11:49983654 T/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs11783469 0.524 rs2235116 chr8:23337410 C/T cg00472375 chr8:23315376 ENTPD4 -0.66 -5.13 -0.42 1.09e-6 Reticulocyte count; TGCT cis rs546131 0.890 rs496558 chr11:34826425 C/T cg11058730 chr11:34937778 PDHX;APIP 0.54 4.78 0.39 4.9100000000000004e-06 Lung disease severity in cystic fibrosis; TGCT cis rs62244186 0.659 rs6441844 chr3:44503579 C/T cg15687855 chr3:44754131 ZNF502 -0.44 -5.11 -0.42 1.17e-6 Depressive symptoms; TGCT cis rs3091242 0.804 rs631133 chr1:25724146 T/C cg00786635 chr1:25594202 NA 0.56 5.63 0.45 1.12e-7 Erythrocyte sedimentation rate; TGCT cis rs9916302 0.904 rs34363096 chr17:37594294 G/A cg07936489 chr17:37558343 FBXL20 -0.61 -4.82 -0.4 4.16e-6 Glomerular filtration rate (creatinine); TGCT cis rs6598955 0.671 rs11247893 chr1:26597086 A/C cg04990556 chr1:26633338 UBXN11 -0.66 -5.08 -0.41 1.38e-6 Obesity-related traits; TGCT cis rs2456568 0.803 rs10831141 chr11:93640728 C/T cg17595323 chr11:93583763 C11orf90 -0.46 -6.15 -0.48 9.78e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9486719 0.895 rs3734239 chr6:96996244 A/G cg18709589 chr6:96969512 KIAA0776 -0.76 -5.32 -0.43 4.63e-7 Migraine;Coronary artery disease; TGCT cis rs6860806 0.507 rs2631362 chr5:131707293 A/G cg24060327 chr5:131705240 SLC22A5 0.76 8.14 0.59 3.46e-13 Breast cancer; TGCT cis rs3733585 0.699 rs2018643 chr4:9947121 C/T cg11266682 chr4:10021025 SLC2A9 0.57 7.23 0.54 4.26e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8180040 0.835 rs6780013 chr3:47452118 G/A cg27129171 chr3:47204927 SETD2 -0.54 -5.86 -0.47 4e-8 Colorectal cancer; TGCT cis rs7674212 0.531 rs7665026 chr4:103936648 T/C cg16532752 chr4:104119610 CENPE -0.6 -5.29 -0.43 5.33e-7 Type 2 diabetes; TGCT cis rs6728642 0.908 rs10203833 chr2:98017363 G/A cg26665480 chr2:98280029 ACTR1B -0.95 -5.34 -0.43 4.21e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs1018836 0.892 rs5005585 chr8:91581975 A/G cg16814680 chr8:91681699 NA -0.78 -8.24 -0.6 2.02e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1941184 0.500 rs55779595 chr18:29015187 C/T cg14871544 chr18:29027885 DSG3 0.44 4.63 0.38 9.18e-6 Parkinson's disease (age of onset); TGCT cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.39 6.86 0.52 2.91e-10 Schizophrenia; TGCT cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg17554472 chr22:41940697 POLR3H -0.42 -4.56 -0.38 1.19e-5 Vitiligo; TGCT cis rs4566357 0.930 rs6436647 chr2:227922958 G/C cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs2243480 1.000 rs1701750 chr7:65467145 T/C cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs7937682 0.883 rs517982 chr11:111462687 T/C cg09085632 chr11:111637200 PPP2R1B -0.98 -9.83 -0.66 3.23e-17 Primary sclerosing cholangitis; TGCT trans rs10506458 0.834 rs12426860 chr12:63387948 C/T cg22491629 chr6:157744540 C6orf35 -0.99 -8.5 -0.61 5.08e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs6969780 0.524 rs12530948 chr7:27201258 C/G cg04321618 chr7:27170880 HOXA4 -0.58 -4.87 -0.4 3.35e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.79e-6 Obesity-related traits; TGCT cis rs2836974 0.965 rs6517538 chr21:40656242 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.45 0.5 2.28e-9 Cognitive function; TGCT cis rs1538970 1.000 rs7417107 chr1:45831915 G/C cg05343316 chr1:45956843 TESK2 0.64 5.13 0.42 1.08e-6 Platelet count; TGCT cis rs7027203 0.828 rs10821229 chr9:96595136 A/C cg14598338 chr9:96623480 NA -0.61 -9.54 -0.65 1.68e-16 DNA methylation (variation); TGCT cis rs478304 0.593 rs4645933 chr11:65485120 C/T cg17480646 chr11:65405466 SIPA1 -0.59 -5.25 -0.43 6.26e-7 Acne (severe); TGCT cis rs1461503 0.966 rs10892936 chr11:122841720 G/A cg27398637 chr11:122830231 C11orf63 -0.42 -5.25 -0.43 6.48e-7 Menarche (age at onset); TGCT cis rs10804591 0.848 rs6782700 chr3:129309147 G/C cg07730360 chr3:128845626 NA -0.19 -4.45 -0.37 1.91e-5 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9467773 1.000 rs6940053 chr6:26562122 C/T cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs2469997 1.000 rs2447163 chr8:120373249 G/A cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs9916302 0.904 rs9898170 chr17:37510092 T/C cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs875971 1.000 rs11974264 chr7:65647582 C/G cg18876405 chr7:65276391 NA -0.33 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs17345786 1.000 rs997739 chr3:101313940 A/G cg11279151 chr3:101281821 RG9MTD1 -0.44 -9.59 -0.65 1.25e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs11578119 0.689 rs12145296 chr1:170389515 C/T cg09767346 chr1:170501363 GORAB -0.57 -4.65 -0.39 8.41e-6 Male-pattern baldness; TGCT cis rs36051895 0.632 rs10815167 chr9:5150058 A/G cg02405213 chr9:5042618 JAK2 -0.75 -9.81 -0.66 3.74e-17 Pediatric autoimmune diseases; TGCT cis rs4654899 0.802 rs6426648 chr1:21179527 A/G cg01072550 chr1:21505969 NA -0.46 -6.91 -0.53 2.3e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4478858 0.735 rs12126725 chr1:31805853 G/T cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT trans rs208520 0.690 rs12192851 chr6:66705862 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.22 0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs12142240 0.698 rs1135459 chr1:46815930 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs875971 0.508 rs10242423 chr7:66059175 A/G cg00343986 chr7:65444356 GUSB -0.2 -4.51 -0.38 1.51e-5 Aortic root size; TGCT cis rs1801251 1.000 rs35212961 chr2:233582762 C/T cg08000102 chr2:233561755 GIGYF2 0.63 6.51 0.5 1.72e-9 Coronary artery disease; TGCT cis rs11098499 0.865 rs4507344 chr4:120307485 C/A cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs7772486 0.720 rs1890171 chr6:146072114 T/C cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7804356 1.000 rs28733208 chr7:26830825 G/A cg03456212 chr7:26904342 SKAP2 -0.63 -4.88 -0.4 3.19e-6 Type 1 diabetes; TGCT cis rs3796352 0.892 rs58515094 chr3:52995575 C/T cg15956490 chr3:53032818 SFMBT1 0.59 6.04 0.48 1.65e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2708977 0.698 rs772160 chr2:97039666 C/A cg14837825 chr2:96917567 TMEM127 0.3 4.44 0.37 1.93e-5 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT trans rs1864982 0.892 rs560150 chr5:146314104 G/A cg14363954 chr9:139437479 NOTCH1 0.41 6.65 0.51 8.27e-10 Alcohol dependence; TGCT cis rs155076 1.000 rs261423 chr13:21852331 A/C cg11317459 chr13:21872234 NA -1.42 -12.26 -0.74 4.07e-23 White matter hyperintensity burden; TGCT cis rs10504229 0.728 rs17215753 chr8:58153764 A/G cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs6951245 0.580 rs78894484 chr7:1138721 T/G cg18402987 chr7:1209562 NA 0.48 4.79 0.39 4.72e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10838532 0.506 rs11038739 chr11:46017895 A/T cg10516359 chr11:45827763 SLC35C1 -0.42 -4.77 -0.39 5.18e-6 Axial length; TGCT cis rs9534288 0.912 rs9526135 chr13:46624992 G/C cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs2075371 0.611 rs1862045 chr7:134023412 A/G cg11752832 chr7:134001865 SLC35B4 0.66 5.37 0.43 3.71e-7 Mean platelet volume; TGCT cis rs74417235 0.610 rs35212808 chr5:154057808 A/G cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs3749237 0.595 rs7637999 chr3:49535115 C/T cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs4699052 0.739 rs6855777 chr4:104242364 C/T cg16532752 chr4:104119610 CENPE 0.5 4.97 0.41 2.18e-6 Testicular germ cell tumor; TGCT cis rs7178572 0.568 rs4886866 chr15:77696166 A/T cg22256960 chr15:77711686 NA -0.87 -8.97 -0.63 3.84e-15 Type 2 diabetes; TGCT cis rs1008375 0.900 rs7658447 chr4:17579415 T/C cg16339924 chr4:17578868 LAP3 0.83 7.06 0.54 1.04e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7809950 1.000 rs2712191 chr7:107182724 C/G cg23024343 chr7:107201750 COG5 -0.35 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs988712 0.672 rs925947 chr11:27667367 G/T cg10635145 chr11:27742435 BDNF -0.38 -5.25 -0.43 6.38e-7 Obesity; TGCT cis rs9430161 0.611 rs2095920 chr1:11033457 T/A cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs3806843 0.735 rs2530241 chr5:140054485 C/T cg19875535 chr5:140030758 IK -0.37 -6.25 -0.49 6.12e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs11122272 0.735 rs2790884 chr1:231531932 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.56 -0.51 1.3e-9 Hemoglobin concentration; TGCT cis rs7169223 0.653 rs12905740 chr15:79082364 C/T cg21242079 chr15:79101063 ADAMTS7 -0.32 -5.29 -0.43 5.38e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs514406 0.861 rs6588443 chr1:53250650 G/A cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs854765 0.624 rs11657130 chr17:17733826 T/C cg09796270 chr17:17721594 SREBF1 -0.27 -5.19 -0.42 8.39e-7 Total body bone mineral density; TGCT cis rs35160687 0.901 rs12472390 chr2:86475083 T/C cg03171300 chr2:86307199 POLR1A 0.32 5.53 0.44 1.83e-7 Night sleep phenotypes; TGCT cis rs17102423 0.963 rs11626496 chr14:65600981 C/G cg11161011 chr14:65562177 MAX -0.5 -6.93 -0.53 2.04e-10 Obesity-related traits; TGCT cis rs17102423 0.964 rs8015330 chr14:65602183 C/T cg11161011 chr14:65562177 MAX -0.49 -6.7 -0.52 6.46e-10 Obesity-related traits; TGCT cis rs6921919 0.583 rs35599905 chr6:28379663 C/T cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs951366 0.559 rs823101 chr1:205667006 T/C cg14159672 chr1:205819179 PM20D1 0.59 6.91 0.53 2.23e-10 Menarche (age at onset); TGCT cis rs3809863 0.602 rs2317677 chr17:45393407 G/A cg08085267 chr17:45401833 C17orf57 -0.66 -7.62 -0.56 5.77e-12 Glaucoma (primary open-angle); TGCT cis rs12544026 0.581 rs520880 chr8:102860827 C/T cg01952226 chr8:102507382 GRHL2 0.27 4.54 0.38 1.31e-5 Major depression and alcohol dependence; TGCT cis rs2235642 1.000 rs2235642 chr16:1584866 T/C cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.35 -0.43 4.01e-7 Coronary artery disease; TGCT cis rs9486719 1.000 rs2472888 chr6:96865501 T/C cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs780096 0.546 rs1104 chr2:27599875 T/G cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.44 -0.37 1.97e-5 Total body bone mineral density; TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs2120019 1.000 rs12185102 chr15:75352201 G/A cg09165964 chr15:75287851 SCAMP5 -1.18 -10.44 -0.68 1.07e-18 Blood trace element (Zn levels); TGCT cis rs7666738 0.791 rs11730069 chr4:98945772 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9640161 0.750 rs59211922 chr7:150023790 T/G cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 9.08e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs6882076 1.000 rs1501908 chr5:156398169 C/G cg12943317 chr5:156479607 HAVCR1 0.29 5.57 0.45 1.5e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs6088590 0.561 rs6059918 chr20:33150503 C/T cg06115741 chr20:33292138 TP53INP2 0.53 4.69 0.39 7.07e-6 Coronary artery disease; TGCT cis rs617219 0.596 rs2131977 chr5:78613916 G/C cg23514016 chr5:78407564 BHMT -0.33 -4.97 -0.41 2.17e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT trans rs731174 0.592 rs11264093 chr1:38194156 G/A cg19725343 chr19:51830960 IGLON5 -0.63 -7.18 -0.54 5.57e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs611744 0.967 rs666821 chr8:109204313 T/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs9611565 0.694 rs202664 chr22:41813886 C/T cg06481639 chr22:41940642 POLR3H 0.71 6.26 0.49 5.75e-9 Vitiligo; TGCT cis rs7216064 0.953 rs75231441 chr17:65885485 A/G cg12091567 chr17:66097778 LOC651250 -0.83 -6.48 -0.5 1.92e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs6463523 0.933 rs4724821 chr7:762544 C/T cg11064039 chr7:766100 PRKAR1B;HEATR2 0.93 11.77 0.73 6.11e-22 Subjective well-being; TGCT cis rs6860806 0.603 rs112300250 chr5:131583292 G/A cg24060327 chr5:131705240 SLC22A5 -0.58 -5.88 -0.47 3.48e-8 Breast cancer; TGCT cis rs7809950 1.000 rs7782057 chr7:107098877 T/A cg23024343 chr7:107201750 COG5 -0.33 -5.27 -0.43 5.81e-7 Coronary artery disease; TGCT cis rs17376456 0.825 rs66564678 chr5:93165894 C/T cg21475434 chr5:93447410 FAM172A 0.66 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs6563842 0.563 rs4575411 chr13:41277794 C/G cg21288729 chr13:41239152 FOXO1 0.93 9.23 0.64 8.96e-16 Eosinophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs9948 0.529 rs62152773 chr2:97448073 T/C cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs9814567 1.000 rs7611611 chr3:134307877 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg15921436 chr17:44337874 NA 0.59 8.06 0.59 5.55e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10876993 0.928 rs10877008 chr12:58103592 A/G cg15848620 chr12:58087721 OS9 -0.72 -5.98 -0.47 2.25e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7618915 1.000 rs3852064 chr3:52349412 G/T cg07507251 chr3:52567010 NT5DC2 0.45 6.02 0.48 1.83e-8 Bipolar disorder; TGCT cis rs6545883 0.965 rs778752 chr2:61776902 C/G cg15711740 chr2:61764176 XPO1 -0.58 -5.36 -0.43 3.92e-7 Tuberculosis; TGCT cis rs4803468 0.967 rs4802116 chr19:41905540 C/T cg09537434 chr19:41945824 ATP5SL -0.89 -10.04 -0.67 9.93e-18 Height; TGCT cis rs9303401 0.615 rs7502342 chr17:56922629 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs1372520 0.684 rs1442144 chr4:90736113 T/C cg15133208 chr4:90757351 SNCA -0.53 -6.29 -0.49 4.94e-9 Neuroticism; TGCT cis rs12142240 0.698 rs9661240 chr1:46827050 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs3087591 0.639 rs2854333 chr17:29713300 T/C cg24425628 chr17:29625626 OMG;NF1 0.41 6.06 0.48 1.48e-8 Hip circumference; TGCT trans rs1496653 0.602 rs35105861 chr3:23529047 A/G cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs61008539 0.853 rs10950611 chr7:861094 G/T cg15782153 chr7:917662 C7orf20 0.49 5.74 0.46 6.99e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs2013441 0.896 rs1812934 chr17:20030960 A/T cg23224458 chr17:20280056 CCDC144C -0.35 -4.44 -0.37 1.95e-5 Obesity-related traits; TGCT cis rs2153535 0.580 rs7341206 chr6:8470489 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7681440 0.904 rs7671549 chr4:90771147 T/A cg20003494 chr4:90757398 SNCA -0.59 -5.52 -0.44 1.9e-7 Dementia with Lewy bodies; TGCT cis rs9611565 0.694 rs5758389 chr22:41941749 T/C cg06481639 chr22:41940642 POLR3H -0.64 -5.89 -0.47 3.42e-8 Vitiligo; TGCT trans rs11764590 0.950 rs62444919 chr7:2109499 C/T cg25206134 chr2:45395956 NA 0.94 6.93 0.53 2e-10 Neuroticism; TGCT cis rs1008375 0.931 rs6813374 chr4:17649494 T/C cg18681998 chr4:17616180 MED28 1.06 12.43 0.74 1.57e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9916302 0.904 rs12952384 chr17:37669536 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.88 -0.4 3.2e-6 Glomerular filtration rate (creatinine); TGCT cis rs67073037 0.911 rs12477538 chr2:29171288 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs11671005 0.735 rs34511020 chr19:58921296 A/G cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.99e-6 Mean platelet volume; TGCT cis rs10760123 1 rs10760123 chr9:123650534 T/G cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.53 0.38 1.35e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs9611565 0.649 rs9623450 chr22:42175231 G/A cg06481639 chr22:41940642 POLR3H 0.53 4.54 0.38 1.29e-5 Vitiligo; TGCT cis rs11148252 0.967 rs11620062 chr13:52994026 T/G cg00495681 chr13:53174319 NA 0.5 5.08 0.42 1.34e-6 Lewy body disease; TGCT cis rs28595532 0.920 rs115271785 chr4:119735748 A/T cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs9858542 0.953 rs9858280 chr3:49597737 T/C cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs10782582 0.593 rs12129523 chr1:76129223 C/A cg22875332 chr1:76189707 ACADM -0.54 -6.21 -0.49 7.36e-9 Daytime sleep phenotypes; TGCT cis rs28386778 0.897 rs7222189 chr17:61836372 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs13108904 0.557 rs1250086 chr4:1248051 G/A cg19318889 chr4:1322082 MAEA -0.2 -5.1 -0.42 1.24e-6 Obesity-related traits; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs7020830 1.000 rs7020830 chr9:37085184 A/T cg14294708 chr9:37120828 ZCCHC7 1.2 18.29 0.85 5.19e-37 Schizophrenia; TGCT cis rs1420338 0.869 rs1362452 chr7:34170519 G/A cg01275685 chr7:34179230 BMPER -0.25 -4.57 -0.38 1.16e-5 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs1862618 0.802 rs42769 chr5:56144152 G/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg15687855 chr3:44754131 ZNF502 -0.52 -6.31 -0.49 4.59e-9 Depressive symptoms; TGCT cis rs597539 0.690 rs635529 chr11:68626294 C/T cg21963583 chr11:68658836 MRPL21 0.37 6.08 0.48 1.39e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9372253 1.000 rs9374170 chr6:110712991 A/G cg13266496 chr6:110720918 DDO -0.45 -5.5 -0.44 2.11e-7 Platelet distribution width; TGCT cis rs9810089 0.843 rs518972 chr3:136039268 C/A cg12473912 chr3:136751656 NA 0.36 5.15 0.42 9.88e-7 Gestational age at birth (child effect); TGCT cis rs7647973 1.000 rs8897 chr3:49460407 A/G cg07636037 chr3:49044803 WDR6 0.63 5.39 0.44 3.48e-7 Menarche (age at onset); TGCT cis rs10791097 0.667 rs2155358 chr11:130740357 T/C cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6141769 0.518 rs6058847 chr20:31324135 C/T cg13636640 chr20:31349939 DNMT3B -0.51 -4.6 -0.38 1.04e-5 Subjective well-being; TGCT cis rs79349575 0.691 rs11079847 chr17:47037024 A/T cg07967210 chr17:47022446 SNF8 -0.42 -5.35 -0.43 4.03e-7 Type 2 diabetes; TGCT cis rs12519773 0.502 rs67862943 chr5:92529268 G/A cg04854328 chr5:92914828 FLJ42709 -0.3 -4.55 -0.38 1.24e-5 Migraine; TGCT cis rs11098499 0.908 rs2017057 chr4:120257711 A/G cg09307838 chr4:120376055 NA 0.63 5.89 0.47 3.41e-8 Corneal astigmatism; TGCT cis rs4148883 0.628 rs34195655 chr4:100073795 C/T cg12011299 chr4:100065546 ADH4 0.38 5.72 0.46 7.71e-8 Alcohol dependence; TGCT cis rs910316 0.967 rs2268619 chr14:75640354 C/G cg08847533 chr14:75593920 NEK9 -0.93 -9.55 -0.65 1.59e-16 Height; TGCT cis rs988712 0.705 rs4923461 chr11:27656910 A/G cg10635145 chr11:27742435 BDNF -0.38 -5.23 -0.43 7e-7 Obesity; TGCT cis rs9638182 0.623 rs13246490 chr7:72992350 C/T cg14087351 chr7:73037990 MLXIPL -0.64 -5.01 -0.41 1.83e-6 Triglycerides; TGCT cis rs7017914 0.934 rs10504479 chr8:71577515 T/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs6733011 0.578 rs10169003 chr2:99508866 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.52 5.2 0.42 8.07e-7 Bipolar disorder; TGCT cis rs453301 0.653 rs11784393 chr8:8903134 C/T cg15556689 chr8:8085844 FLJ10661 0.88 7.98 0.58 8.36e-13 Joint mobility (Beighton score); TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs6088580 0.634 rs6088488 chr20:32992631 T/C cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs2153535 0.601 rs2327059 chr6:8447071 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs2075371 0.830 rs12669960 chr7:133931782 A/G cg11752832 chr7:134001865 SLC35B4 0.63 5.16 0.42 9.38e-7 Mean platelet volume; TGCT cis rs151997 0.630 rs26064 chr5:50217806 T/C cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs1056107 0.931 rs4979089 chr9:114999096 C/T cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs10927875 0.518 rs945416 chr1:16344402 G/A cg21385522 chr1:16154831 NA 0.47 4.85 0.4 3.57e-6 Dilated cardiomyopathy; TGCT cis rs7809950 0.817 rs3779495 chr7:107250260 G/A cg23024343 chr7:107201750 COG5 0.43 6.16 0.48 9.49e-9 Coronary artery disease; TGCT cis rs9467711 0.790 rs45527431 chr6:26599509 A/G cg12315302 chr6:26189340 HIST1H4D 0.99 4.44 0.37 1.93e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs6754311 0.509 rs10188066 chr2:136539513 G/A cg07169764 chr2:136633963 MCM6 -0.71 -6.41 -0.5 2.69e-9 Mosquito bite size; TGCT cis rs1635 0.655 rs723475 chr6:28304841 G/T cg15743358 chr6:28303923 ZNF323 1.29 6.5 0.5 1.73e-9 Schizophrenia; TGCT cis rs9549367 0.774 rs9549364 chr13:113903745 T/C cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs7614311 0.731 rs17401592 chr3:63954490 A/G cg22134162 chr3:63841271 THOC7 -0.45 -5.73 -0.46 7.3e-8 Lung function (FVC);Lung function (FEV1); TGCT cis rs9527 0.590 rs12246739 chr10:104787019 A/C cg04362960 chr10:104952993 NT5C2 -0.64 -5.18 -0.42 8.55e-7 Arsenic metabolism; TGCT cis rs11098499 0.865 rs4001305 chr4:120359236 G/T cg09307838 chr4:120376055 NA 0.71 6.98 0.53 1.57e-10 Corneal astigmatism; TGCT cis rs7618915 0.547 rs11130311 chr3:52675005 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs1371867 0.846 rs1788167 chr8:101319996 C/T cg06002616 chr8:101225028 SPAG1 -0.53 -6.21 -0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs612683 0.599 rs2809823 chr1:101003762 C/A cg06223162 chr1:101003688 GPR88 0.43 8.81 0.62 9.45e-15 Breast cancer; TGCT cis rs9894429 0.738 rs8077038 chr17:79577127 T/G cg21984481 chr17:79567631 NPLOC4 0.26 4.9 0.4 2.91e-6 Eye color traits; TGCT cis rs1971762 0.527 rs784568 chr12:53927554 C/A cg16917193 chr12:54089295 NA -1.05 -10.82 -0.7 1.27e-19 Height; TGCT cis rs2836974 0.932 rs6517523 chr21:40557332 T/C cg11644478 chr21:40555479 PSMG1 0.99 10.5 0.69 7.73e-19 Cognitive function; TGCT cis rs9325144 0.647 rs12822023 chr12:39097964 T/C cg10518543 chr12:38710700 ALG10B -0.49 -4.58 -0.38 1.11e-5 Morning vs. evening chronotype; TGCT cis rs986417 0.901 rs8020867 chr14:61093246 A/T cg27398547 chr14:60952738 C14orf39 1.48 8.31 0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs13118159 0.899 rs3796613 chr4:1353321 A/T cg13395646 chr4:1353034 KIAA1530 -0.43 -4.89 -0.4 3.08e-6 Longevity; TGCT cis rs71636778 0.509 rs11807824 chr1:27270338 A/C cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs4836694 0.574 rs3780712 chr9:132943082 A/G cg05251000 chr9:132935664 FREQ 0.53 5.84 0.46 4.35e-8 Alzheimer's disease (cognitive decline); TGCT cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 -0.64 -4.6 -0.38 1.04e-5 Tuberculosis; TGCT cis rs9486719 1.000 rs12190508 chr6:96898269 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs12220898 0.584 rs10857455 chr10:50474712 A/T cg06072769 chr10:50146962 WDFY4 0.36 4.67 0.39 7.64e-6 Inflammatory biomarkers; TGCT cis rs6545883 0.931 rs778765 chr2:61786385 A/T cg15711740 chr2:61764176 XPO1 -0.57 -5.1 -0.42 1.22e-6 Tuberculosis; TGCT cis rs4149178 0.656 rs3734683 chr6:43316023 A/G cg12269535 chr6:43142014 SRF 0.61 5.14 0.42 1.02e-6 Urate levels; TGCT cis rs11585357 0.947 rs11585118 chr1:17605774 C/A cg08277548 chr1:17600880 PADI3 -0.97 -9.95 -0.67 1.7e-17 Hair shape; TGCT cis rs9811920 0.683 rs4928230 chr3:99661963 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.4 4.88 0.4 3.17e-6 Axial length; TGCT cis rs12134133 0.962 rs6682586 chr1:207416467 A/C cg02152968 chr1:207494213 CD55 0.61 4.74 0.39 5.83e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs9467773 0.620 rs2504600 chr6:26648334 C/A cg26531700 chr6:26746687 NA 0.51 4.61 0.38 9.86e-6 Intelligence (multi-trait analysis); TGCT cis rs8050907 0.744 rs13330957 chr16:4525330 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs12477438 0.765 rs72957180 chr2:99694452 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs3780378 0.870 rs7034878 chr9:5058991 G/T cg02405213 chr9:5042618 JAK2 0.54 6.87 0.53 2.75e-10 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT trans rs57221529 0.825 rs7443550 chr5:578404 G/T cg11887960 chr12:57824829 NA 1.1 9.44 0.65 2.89e-16 Lung disease severity in cystic fibrosis; TGCT cis rs13118159 0.550 rs4974611 chr4:1358449 T/C cg19318889 chr4:1322082 MAEA 0.27 6.66 0.51 8.13e-10 Longevity; TGCT cis rs1059312 0.778 rs4760594 chr12:129296865 T/A cg09035930 chr12:129282057 SLC15A4 0.55 10.73 0.69 2.06e-19 Systemic lupus erythematosus; TGCT cis rs9906944 0.933 rs4794018 chr17:47093398 T/C cg07075026 chr17:47091521 IGF2BP1 -0.45 -4.87 -0.4 3.33e-6 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs11673344 0.504 rs11666786 chr19:37624849 C/T cg08039142 chr19:36980659 ZNF566 0.51 4.62 0.38 9.29e-6 Obesity-related traits; TGCT cis rs7772486 0.790 rs7753092 chr6:146248863 C/T cg23711669 chr6:146136114 FBXO30 -0.88 -10.27 -0.68 2.84e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9297145 0.761 rs62473005 chr7:98742510 G/C cg05967295 chr7:98741636 SMURF1 1.01 12.87 0.76 1.33e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs3849570 0.555 rs9968070 chr3:82010368 G/A cg07356753 chr3:81810745 GBE1 -0.62 -5.38 -0.44 3.5e-7 Waist circumference;Body mass index; TGCT cis rs7954584 0.546 rs10840630 chr12:122352445 C/T cg21171335 chr12:122356390 WDR66 0.7 7.02 0.53 1.25e-10 Mean corpuscular volume; TGCT cis rs73001065 1.000 rs73001065 chr19:19460541 G/C cg03709012 chr19:19516395 GATAD2A 1.08 5.01 0.41 1.83e-6 LDL cholesterol; TGCT cis rs7208859 0.673 rs73265612 chr17:29225983 A/G cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10901296 0.588 rs12003046 chr9:133741626 T/C cg01000188 chr9:133769184 QRFP 0.33 4.57 0.38 1.18e-5 Bilirubin levels; TGCT cis rs6860806 0.507 rs273912 chr5:131661349 A/C cg24060327 chr5:131705240 SLC22A5 0.8 7.9 0.58 1.3e-12 Breast cancer; TGCT cis rs7666738 0.716 rs9994641 chr4:99101605 C/T cg18180107 chr4:99064573 C4orf37 0.52 4.66 0.39 8.01e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2458413 0.669 rs12681140 chr8:105346112 A/C cg04554929 chr8:105342491 NA 0.6 9.37 0.64 4.33e-16 Paget's disease; TGCT cis rs7027203 0.797 rs3996254 chr9:96591239 A/G cg14396892 chr9:96623032 NA -0.26 -5.46 -0.44 2.51e-7 DNA methylation (variation); TGCT cis rs832540 0.931 rs832534 chr5:56213672 G/A cg12311346 chr5:56204834 C5orf35 -0.47 -4.97 -0.41 2.15e-6 Coronary artery disease; TGCT cis rs416603 0.967 rs11644184 chr16:11365104 G/A cg00044050 chr16:11439710 C16orf75 -0.82 -8.44 -0.6 6.82e-14 Type 1 diabetes; TGCT cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg06481639 chr22:41940642 POLR3H -0.6 -5.23 -0.43 6.98e-7 Vitiligo; TGCT cis rs4273100 0.607 rs1043809 chr17:19239432 C/T cg01534423 chr17:18965556 NA -0.79 -7.19 -0.54 5.25e-11 Schizophrenia; TGCT cis rs796364 0.806 rs79156935 chr2:200913822 T/G cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs1215050 0.740 rs783936 chr4:98928628 G/T cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.12e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs514406 0.505 rs436363 chr1:53172163 T/C cg22166914 chr1:53195759 ZYG11B 0.45 7.74 0.57 3.05e-12 Monocyte count; TGCT cis rs11673344 0.542 rs826331 chr19:37498262 G/A cg08039142 chr19:36980659 ZNF566 0.56 5.35 0.43 4.02e-7 Obesity-related traits; TGCT cis rs1371867 0.846 rs1660346 chr8:101312497 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs9790314 0.791 rs6809256 chr3:161026513 G/A cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs3796352 0.667 rs3755805 chr3:52866299 G/A cg15956490 chr3:53032818 SFMBT1 0.57 5.25 0.43 6.25e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9393777 0.513 rs9368447 chr6:26646674 A/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs9915657 0.803 rs12449851 chr17:70099002 C/T cg06234051 chr17:70120541 SOX9 0.26 5.41 0.44 3.14e-7 Thyroid hormone levels; TGCT cis rs17784882 0.521 rs11713693 chr3:47074906 T/C cg27129171 chr3:47204927 SETD2 -0.67 -7.68 -0.57 4.15e-12 QT interval; TGCT cis rs9611565 0.592 rs80477 chr22:42001183 C/T cg06481639 chr22:41940642 POLR3H 0.62 5.29 0.43 5.4e-7 Vitiligo; TGCT cis rs9818758 0.607 rs13077498 chr3:49313978 C/T cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9952991 0.941 rs7237497 chr18:12777325 T/C cg23598886 chr18:12777645 NA 0.62 5.9 0.47 3.25e-8 Inflammatory skin disease; TGCT cis rs28595532 0.920 rs115437723 chr4:119741828 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9914988 0.887 rs4795464 chr17:27146497 G/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7208859 0.623 rs3794796 chr17:29130880 G/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.66e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7959452 0.562 rs10878975 chr12:69782044 G/C cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg03452623 chr4:187889614 NA 0.37 5.63 0.45 1.16e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs17473412 0.864 rs13436337 chr5:122681230 G/C cg15125798 chr5:122621645 NA -0.55 -5.01 -0.41 1.84e-6 Total body bone mineral density; TGCT cis rs66573146 1.000 rs73088528 chr4:6967747 G/C cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs941408 1.000 rs941410 chr19:2787329 G/A cg06609049 chr19:2785107 THOP1 0.84 8.47 0.61 6.01e-14 Total cholesterol levels; TGCT cis rs12681288 0.894 rs66739903 chr8:1010492 C/A cg04851639 chr8:1020857 NA -0.32 -5.32 -0.43 4.59e-7 Schizophrenia; TGCT cis rs916888 0.773 rs199447 chr17:44812188 C/T cg15921436 chr17:44337874 NA 0.56 7.75 0.57 2.88e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12643440 0.538 rs6834807 chr4:17138244 T/C cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs9581857 0.547 rs9581871 chr13:28085767 G/A cg22138327 chr13:27999177 GTF3A 0.73 4.54 0.38 1.34e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs1552244 0.832 rs67145301 chr3:10197314 G/A cg00149659 chr3:10157352 C3orf10 1.05 5.81 0.46 4.95e-8 Alzheimer's disease; TGCT cis rs9303401 0.538 rs8078280 chr17:56473132 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.69 6.56 0.51 1.3e-9 Cognitive test performance; TGCT cis rs587847 0.708 rs28588437 chr15:37632513 G/T cg00216138 chr15:37171175 LOC145845 0.32 4.74 0.39 5.71e-6 Intraocular pressure; TGCT cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.1 14.88 0.8 2.36e-29 Height; TGCT cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg13866156 chr1:1669148 SLC35E2 -0.21 -5.12 -0.42 1.13e-6 Body mass index; TGCT cis rs9926296 0.533 rs7190823 chr16:89866043 A/G cg21285383 chr16:89894308 SPIRE2 0.45 7.13 0.54 7.2e-11 Vitiligo; TGCT cis rs3540 1.000 rs3540 chr15:91045408 G/A cg22089800 chr15:90895588 ZNF774 0.79 7.8 0.57 2.17e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs17767294 0.708 rs77689085 chr6:28072536 G/A cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs12908161 1.000 rs12908161 chr15:85207825 A/G cg11189052 chr15:85197271 WDR73 0.75 6.3 0.49 4.8e-9 Schizophrenia; TGCT cis rs3820928 0.874 rs10933165 chr2:227883648 C/G cg11843606 chr2:227700838 RHBDD1 0.54 5.02 0.41 1.72e-6 Pulmonary function; TGCT cis rs9733 0.519 rs7511673 chr1:150707636 A/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs16867321 0.671 rs4667318 chr2:181516693 G/A cg23363182 chr2:181467187 NA -0.44 -4.59 -0.38 1.09e-5 Obesity; TGCT cis rs2066819 1.000 rs79824801 chr12:56728137 T/C cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs6534347 0.551 rs1398553 chr4:123548068 A/G cg10583651 chr4:123538969 IL21 -0.31 -4.51 -0.38 1.49e-5 Type 1 diabetes; TGCT cis rs736408 0.511 rs12637632 chr3:52708073 A/T cg10802521 chr3:52805072 NEK4 -0.72 -8.98 -0.63 3.75e-15 Bipolar disorder; TGCT cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6490294 0.904 rs11066112 chr12:112416586 C/T cg10833066 chr12:111807467 FAM109A 0.35 5.13 0.42 1.09e-6 Mean platelet volume; TGCT cis rs4819052 0.851 rs2838843 chr21:46669284 T/C cg06618935 chr21:46677482 NA -0.37 -5.58 -0.45 1.41e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1372520 0.745 rs2736994 chr4:90784528 A/G cg15133208 chr4:90757351 SNCA -0.48 -5.48 -0.44 2.28e-7 Neuroticism; TGCT cis rs981844 0.683 rs1037655 chr4:154750408 A/G cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs6558530 0.666 rs7005699 chr8:1700620 A/T cg09410841 chr8:1729607 CLN8 0.72 6.49 0.5 1.87e-9 Systolic blood pressure; TGCT cis rs7772486 0.686 rs2072911 chr6:146056801 G/A cg23711669 chr6:146136114 FBXO30 -0.87 -9.51 -0.65 1.94e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs950776 0.518 rs952216 chr15:78819202 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs4319547 0.586 rs7956480 chr12:122817507 A/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.58 -0.38 1.11e-5 Body mass index; TGCT cis rs9467711 0.606 rs9366656 chr6:26434630 T/C cg16898833 chr6:26189333 HIST1H4D 1.12 5.36 0.43 3.91e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4237845 0.735 rs11172375 chr12:58291574 G/C cg02175503 chr12:58329896 NA 0.52 4.86 0.4 3.52e-6 Intelligence (multi-trait analysis); TGCT cis rs34638657 0.732 rs7205534 chr16:82201618 C/T cg09439754 chr16:82129088 HSD17B2 -0.24 -4.72 -0.39 6.21e-6 Lung adenocarcinoma; TGCT cis rs9393777 1.000 rs9393777 chr6:26942027 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.58 -4.63 -0.38 9.02e-6 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.784 rs4699602 chr4:99034903 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.84 0.46 4.24e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs617219 0.765 rs10053349 chr5:78475423 T/C cg05890484 chr5:78407552 BHMT 0.38 5.23 0.42 7.13e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9467773 1.000 rs6932156 chr6:26571506 T/G cg15659132 chr6:26577336 NA 0.88 12.27 0.74 3.83e-23 Intelligence (multi-trait analysis); TGCT cis rs3820928 1.000 rs10193404 chr2:227777757 A/G cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs7666738 0.791 rs11097610 chr4:99011795 C/G cg17366294 chr4:99064904 C4orf37 0.66 6.63 0.51 9.33e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9788682 0.747 rs2568485 chr15:78752114 C/T cg24631222 chr15:78858424 CHRNA5 -0.61 -4.55 -0.38 1.25e-5 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs344364 0.511 rs62040571 chr16:1948514 C/G cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9467773 0.596 rs3001369 chr6:26670969 C/T cg02458000 chr6:26745757 NA 0.56 4.83 0.4 3.89e-6 Intelligence (multi-trait analysis); TGCT cis rs951366 0.585 rs72750964 chr1:205675240 C/T cg17178900 chr1:205818956 PM20D1 0.58 7.13 0.54 7.41e-11 Menarche (age at onset); TGCT cis rs763014 0.932 rs7204439 chr16:661335 T/C cg27436995 chr16:743998 FBXL16 -0.44 -4.81 -0.4 4.32e-6 Height; TGCT cis rs9291683 0.588 rs3756238 chr4:10013202 C/T cg11266682 chr4:10021025 SLC2A9 0.73 11.04 0.7 3.63e-20 Bone mineral density; TGCT cis rs6690583 0.524 rs12029690 chr1:85452867 C/G cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs4595586 0.545 rs11615700 chr12:39365104 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs4711350 0.765 rs6921772 chr6:33749686 A/G cg18005901 chr6:33739558 LEMD2 -0.59 -6.65 -0.51 8.34e-10 Schizophrenia; TGCT cis rs7216064 0.553 rs62084690 chr17:66035411 A/G cg12091567 chr17:66097778 LOC651250 0.8 6.67 0.51 7.53e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg16145915 chr7:1198662 ZFAND2A -0.42 -4.89 -0.4 3.08e-6 Longevity;Endometriosis; TGCT cis rs6061231 0.631 rs2427317 chr20:60975725 C/T cg24112000 chr20:60950667 NA -0.35 -4.91 -0.4 2.77e-6 Colorectal cancer; TGCT cis rs2278034 0.502 rs3747672 chr3:195612034 T/C cg01181863 chr3:195395398 SDHAP2 -0.34 -4.75 -0.39 5.5e-6 Bronchopulmonary dysplasia; TGCT cis rs2839186 0.709 rs2839176 chr21:47678173 A/G cg13732083 chr21:47605072 C21orf56 0.34 4.74 0.39 5.86e-6 Testicular germ cell tumor; TGCT cis rs4819052 0.724 rs9753962 chr21:46661384 G/T cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2486012 0.655 rs2906598 chr1:44372290 C/G cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs79057730 0.528 rs6965219 chr7:821807 C/G cg06242242 chr7:766104 PRKAR1B;HEATR2 0.63 5.13 0.42 1.09e-6 Initial pursuit acceleration; TGCT cis rs10504229 0.679 rs7839948 chr8:58130607 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.683 rs72649188 chr8:58108829 A/G cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs3785574 0.962 rs58131426 chr17:61854375 T/C cg11494091 chr17:61959527 GH2 0.43 7.51 0.56 9.88e-12 Height; TGCT cis rs1799949 1.000 rs33946455 chr17:41321846 C/T cg05368731 chr17:41323189 NBR1 1.2 14.38 0.79 3.45e-28 Menopause (age at onset); TGCT cis rs9611565 0.765 rs202659 chr22:41811620 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg26354017 chr1:205819088 PM20D1 -0.55 -6.82 -0.52 3.49e-10 Monocyte percentage of white cells; TGCT cis rs13118159 0.801 rs13147602 chr4:1332175 A/G cg20887711 chr4:1340912 KIAA1530 0.52 4.49 0.37 1.62e-5 Longevity; TGCT cis rs881375 0.935 rs7034390 chr9:123646488 A/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.49 5.49 0.44 2.19e-7 Rheumatoid arthritis; TGCT cis rs10489525 0.599 rs7526323 chr1:115604241 G/A cg12756093 chr1:115239321 AMPD1 -0.4 -5.49 -0.44 2.19e-7 Autism; TGCT cis rs4819052 0.851 rs2838839 chr21:46667858 C/G cg06618935 chr21:46677482 NA 0.38 5.76 0.46 6.27e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg20007245 chr22:24372913 LOC391322 -0.74 -7.49 -0.56 1.11e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2361718 0.500 rs4889818 chr17:78085228 A/G cg09238746 chr17:78121135 EIF4A3 -1.03 -9.67 -0.66 8.14e-17 Yeast infection; TGCT cis rs10435719 0.902 rs7006538 chr8:11804982 A/G cg02840367 chr8:11660030 FDFT1 -0.52 -4.48 -0.37 1.7e-5 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs7772486 0.720 rs6901888 chr6:146023144 A/G cg13319975 chr6:146136371 FBXO30 0.53 4.8 0.4 4.49e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs112591243 0.685 rs113059032 chr21:47751646 C/T cg10657630 chr21:48055338 PRMT2 1.06 5.76 0.46 6.29e-8 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1862618 0.529 rs978406 chr5:56259808 A/T cg24549020 chr5:56110836 MAP3K1 -0.67 -4.85 -0.4 3.66e-6 Initial pursuit acceleration; TGCT cis rs1577917 1.000 rs1337844 chr6:86677273 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.39e-7 Response to antipsychotic treatment; TGCT cis rs4886920 0.537 rs6495247 chr15:78069431 C/T cg03457338 chr15:78040120 NA -0.21 -5.23 -0.43 6.96e-7 Neuroticism; TGCT cis rs7267979 1.000 rs2257991 chr20:25270339 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs752092 1.000 rs8033360 chr15:101778710 C/A cg19997662 chr15:101784653 CHSY1 -0.31 -5.81 -0.46 4.9e-8 Corneal structure; TGCT cis rs9948 0.786 rs62156233 chr2:97434061 C/G cg01990225 chr2:97406019 LMAN2L -0.79 -4.98 -0.41 2.12e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs28386778 0.897 rs2727330 chr17:61925498 A/G cg26338869 chr17:61819248 STRADA 0.53 5.19 0.42 8.45e-7 Prudent dietary pattern; TGCT cis rs904251 0.523 rs1757191 chr6:37482871 C/T cg01843034 chr6:37503916 NA -0.54 -7.32 -0.55 2.76e-11 Cognitive performance; TGCT cis rs896854 0.715 rs12548874 chr8:95935164 A/C cg09323728 chr8:95962352 TP53INP1 0.49 5.82 0.46 4.79e-8 Type 2 diabetes; TGCT cis rs1005277 0.602 rs1740743 chr10:38519222 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.04 -0.59 5.95e-13 Extrinsic epigenetic age acceleration; TGCT cis rs10769945 0.592 rs1635155 chr11:1972919 G/T cg18032502 chr11:1949113 TNNT3 -0.25 -4.82 -0.4 4.06e-6 DNA methylation (variation); TGCT trans rs6561151 0.681 rs17462017 chr13:44472235 C/T cg12856521 chr11:46389249 DGKZ 0.77 7.12 0.54 7.74e-11 Crohn's disease; TGCT trans rs1005277 0.579 rs9418322 chr10:38377296 G/T cg27523141 chr10:43048294 ZNF37B 0.73 8.39 0.6 9.23e-14 Extrinsic epigenetic age acceleration; TGCT cis rs2839186 0.616 rs4819213 chr21:47619300 G/A cg13732083 chr21:47605072 C21orf56 -0.35 -4.51 -0.38 1.5e-5 Testicular germ cell tumor; TGCT cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg13395646 chr4:1353034 KIAA1530 -0.36 -4.57 -0.38 1.14e-5 Obesity-related traits; TGCT cis rs11577318 0.579 rs35456934 chr1:26686864 G/A cg14210634 chr1:25870291 LDLRAP1 0.54 4.73 0.39 6.06e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs11122272 0.735 rs2491407 chr1:231518928 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs2820315 0.867 rs2820318 chr1:201878620 T/C cg12730843 chr1:201915899 LMOD1 -0.28 -5.13 -0.42 1.07e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs1568889 1.000 rs7937778 chr11:28104605 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs7666738 0.618 rs10856932 chr4:98819992 C/T cg05340658 chr4:99064831 C4orf37 0.51 6.03 0.48 1.76e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7085104 0.700 rs6163 chr10:104596924 C/A cg05855489 chr10:104503620 C10orf26 0.54 4.88 0.4 3.15e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7296418 0.961 rs10848428 chr12:123572495 C/T cg00376283 chr12:123451042 ABCB9 0.82 7.46 0.56 1.33e-11 Platelet count; TGCT cis rs1461503 0.932 rs10892934 chr11:122837950 C/T cg27398637 chr11:122830231 C11orf63 -0.43 -5.32 -0.43 4.69e-7 Menarche (age at onset); TGCT cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs1799949 1.000 rs1399323 chr17:41332330 T/C cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs892961 0.932 rs7216155 chr17:75405155 C/G cg05865280 chr17:75406074 SEPT9 0.29 6.76 0.52 4.91e-10 Airflow obstruction; TGCT trans rs1814175 0.817 rs4881627 chr11:49953955 C/A cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs2153535 0.563 rs1737586 chr6:8535897 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.63 0.45 1.14e-7 Motion sickness; TGCT cis rs17376456 0.569 rs11135394 chr5:93187135 C/T cg21475434 chr5:93447410 FAM172A -0.64 -5.89 -0.47 3.35e-8 Diabetic retinopathy; TGCT cis rs12477438 0.798 rs1349778 chr2:99645011 G/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.31 -0.6 1.43e-13 Chronic sinus infection; TGCT cis rs9302001 0.881 rs9516481 chr13:95469560 C/T cg07483244 chr13:95358924 NA 0.36 4.7 0.39 6.89e-6 Panic disorder; TGCT cis rs4727027 0.704 rs12704071 chr7:148904795 C/T cg23583168 chr7:148888333 NA -0.83 -10.88 -0.7 8.98e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs4077515 0.934 rs78428995 chr9:139281847 T/C cg13741927 chr9:139327495 INPP5E -0.2 -4.6 -0.38 1.01e-5 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs9682041 0.808 rs9880558 chr3:170067771 A/G cg07589077 chr3:170072950 NA -0.32 -5.28 -0.43 5.69e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs1635 0.655 rs10484542 chr6:28309753 C/T cg15743358 chr6:28303923 ZNF323 -0.85 -4.57 -0.38 1.17e-5 Schizophrenia; TGCT cis rs28374715 0.681 rs7162231 chr15:41591859 G/A cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.62 -0.8 9.13e-29 Ulcerative colitis; TGCT cis rs3806843 0.576 rs251373 chr5:140252615 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 0.43 5.17 0.42 8.91e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg08280861 chr8:58055591 NA 0.39 4.64 0.38 8.72e-6 Developmental language disorder (linguistic errors); TGCT cis rs9677476 0.517 rs2368563 chr2:232058493 A/G cg07929768 chr2:232055508 NA 0.3 4.83 0.4 4.01e-6 Food antigen IgG levels; TGCT cis rs12681288 0.550 rs59004371 chr8:962393 T/C cg04851639 chr8:1020857 NA -0.3 -5.08 -0.41 1.36e-6 Schizophrenia; TGCT cis rs981844 1.000 rs56331473 chr4:154668052 C/A cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs612683 0.524 rs11166456 chr1:100925633 C/T cg06223162 chr1:101003688 GPR88 0.3 4.93 0.41 2.53e-6 Breast cancer; TGCT cis rs7523273 0.606 rs12401619 chr1:207976276 G/C cg22525895 chr1:207977042 MIR29B2 -0.53 -9.07 -0.63 2.17e-15 Schizophrenia; TGCT cis rs6570726 0.791 rs436156 chr6:145874873 A/G cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs916888 0.773 rs199533 chr17:44828931 G/A cg10053473 chr17:62856997 LRRC37A3 -0.46 -6.7 -0.52 6.41e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9394169 0.536 rs3998115 chr6:33784833 G/C cg00334056 chr6:33755658 LEMD2 -0.28 -4.9 -0.4 2.97e-6 Essential tremor; TGCT cis rs6951245 1.000 rs77083167 chr7:1071823 C/T cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs17685 0.697 rs2302437 chr7:75677016 G/A cg19862616 chr7:65841803 NCRNA00174 -0.52 -8.84 -0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7180079 0.620 rs6494487 chr15:64998248 T/A cg03791955 chr15:65024147 NA 0.28 5.45 0.44 2.61e-7 Monocyte count; TGCT cis rs2033711 0.837 rs3764535 chr19:58929052 G/A cg04608855 chr19:58913158 NA 0.58 5.69 0.46 8.64e-8 Uric acid clearance; TGCT cis rs3008870 1.000 rs12044278 chr1:67460977 T/C cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs7017914 0.905 rs3110244 chr8:71933197 C/T cg23757474 chr8:71581111 LACTB2;XKR9 0.52 4.74 0.39 5.73e-6 Bone mineral density; TGCT cis rs1784581 0.802 rs9365355 chr6:162414604 A/G cg17173639 chr6:162384350 PARK2 0.42 7.3 0.55 3.02e-11 Itch intensity from mosquito bite; TGCT cis rs3125734 0.633 rs6479804 chr10:64048327 T/C cg19640130 chr10:64028056 RTKN2 -0.38 -4.79 -0.39 4.73e-6 Rheumatoid arthritis; TGCT cis rs6725041 0.819 rs13420153 chr2:213083191 C/G cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT cis rs9814567 0.806 rs6799543 chr3:134216139 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9926296 0.585 rs1800337 chr16:89845194 A/G cg26513180 chr16:89883248 FANCA 1.06 14.53 0.79 1.56e-28 Vitiligo; TGCT cis rs903263 0.965 rs7515264 chr1:84599832 C/T cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.73e-6 Breast cancer (male); TGCT cis rs2836974 0.666 rs1888487 chr21:40683259 A/G cg11890956 chr21:40555474 PSMG1 -0.78 -7.27 -0.55 3.48e-11 Cognitive function; TGCT cis rs6089584 0.854 rs6061407 chr20:60622048 A/C cg13770153 chr20:60521292 NA -0.54 -7.12 -0.54 7.73e-11 Body mass index; TGCT cis rs801193 0.967 rs3800823 chr7:66147110 C/A cg18876405 chr7:65276391 NA -0.38 -5.83 -0.46 4.44e-8 Aortic root size; TGCT cis rs763121 0.853 rs138713 chr22:39142615 T/C cg06022373 chr22:39101656 GTPBP1 0.69 6.39 0.5 3.1e-9 Menopause (age at onset); TGCT cis rs2932538 0.961 rs3013441 chr1:113192605 C/T cg22728128 chr1:112299491 DDX20;C1orf183 -0.25 -4.72 -0.39 6.22e-6 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9527 0.590 rs10883818 chr10:104759586 A/G cg15744005 chr10:104629667 AS3MT -0.44 -5.11 -0.42 1.18e-6 Arsenic metabolism; TGCT cis rs3820928 1.000 rs2396433 chr2:227772502 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -4.82 -0.4 4.12e-6 Pulmonary function; TGCT cis rs769267 0.930 rs1865034 chr19:19605763 C/T cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs3749237 0.555 rs7637665 chr3:49552295 T/C cg02487422 chr3:49467188 NICN1 0.57 5.84 0.46 4.26e-8 Resting heart rate; TGCT cis rs8062405 0.690 rs6498089 chr16:28629300 C/T cg09754948 chr16:28834200 ATXN2L -0.59 -4.78 -0.39 4.82e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6088580 0.634 rs4911152 chr20:32955024 T/C cg06115741 chr20:33292138 TP53INP2 -0.55 -4.8 -0.4 4.5e-6 Glomerular filtration rate (creatinine); TGCT cis rs6429082 0.764 rs291369 chr1:235691913 T/C cg26050004 chr1:235667680 B3GALNT2 0.6 5.25 0.43 6.36e-7 Adiposity; TGCT cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Electroencephalogram traits; TGCT cis rs12048904 0.595 rs2295280 chr1:101342497 T/C cg15686842 chr1:101360669 SLC30A7;EXTL2 0.63 6.07 0.48 1.42e-8 Multiple sclerosis; TGCT cis rs6951245 1.000 rs6951245 chr7:1058193 G/A cg18402987 chr7:1209562 NA 0.65 5.32 0.43 4.65e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs35934224 0.783 rs7285948 chr22:19861127 T/C cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.04e-7 Glaucoma (primary open-angle); TGCT cis rs709400 0.628 rs11623470 chr14:104004810 T/A cg12935359 chr14:103987150 CKB -0.38 -5.67 -0.45 9.37e-8 Body mass index; TGCT cis rs739496 0.542 rs10849937 chr12:111792427 A/G cg10833066 chr12:111807467 FAM109A 0.45 7.67 0.57 4.32e-12 Platelet count; TGCT cis rs9911578 0.935 rs117819974 chr17:57002324 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs6570726 0.935 rs585292 chr6:145862228 T/C cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs250677 0.522 rs10042466 chr5:148393634 T/C cg18129178 chr5:148520854 ABLIM3 -0.36 -4.62 -0.38 9.43e-6 Breast cancer; TGCT cis rs1568889 0.838 rs10835283 chr11:28214985 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.91 9.94 0.67 1.75e-17 Bipolar disorder; TGCT cis rs9611565 0.512 rs5758436 chr22:42124265 C/T cg03806693 chr22:41940476 POLR3H 1.08 11.99 0.73 1.84e-22 Vitiligo; TGCT cis rs4819052 1.000 rs2297284 chr21:46705345 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.97 7.57 0.56 7.23e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1371867 0.817 rs1660315 chr8:101332956 G/A cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs4664308 0.935 rs4665148 chr2:160917901 A/G cg03641300 chr2:160917029 PLA2R1 -0.27 -6.58 -0.51 1.2e-9 Idiopathic membranous nephropathy; TGCT cis rs10504229 1.000 rs67237174 chr8:58175776 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs12134245 0.776 rs12125947 chr1:91990487 T/C cg25838465 chr1:92012736 NA -0.42 -6.6 -0.51 1.09e-9 Breast cancer; TGCT cis rs12477438 0.520 rs11890338 chr2:99767868 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs71435601 0.574 rs528113 chr2:21382624 G/T cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs1865721 0.656 rs724765 chr18:73139794 A/G cg26385618 chr18:73139727 C18orf62 -0.23 -4.5 -0.37 1.55e-5 Intelligence; TGCT cis rs13191362 1.000 rs35383933 chr6:163002869 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7095607 0.785 rs3956957 chr10:69919445 A/T cg18986048 chr10:69913749 MYPN 0.41 4.48 0.37 1.66e-5 Lung function (FVC); TGCT cis rs9894429 0.608 rs7406219 chr17:79609410 G/T cg18240062 chr17:79603768 NPLOC4 0.56 4.92 0.4 2.67e-6 Eye color traits; TGCT cis rs6429082 0.818 rs291391 chr1:235649955 A/G cg26050004 chr1:235667680 B3GALNT2 0.62 5.58 0.45 1.43e-7 Adiposity; TGCT cis rs7940866 0.834 rs7939417 chr11:130853832 T/A cg12179176 chr11:130786555 SNX19 0.61 5.88 0.47 3.59e-8 Schizophrenia; TGCT cis rs2019216 0.500 rs12946184 chr17:21944675 A/C cg22648282 chr17:21454238 C17orf51 -0.58 -4.95 -0.41 2.37e-6 Pelvic organ prolapse; TGCT cis rs736408 0.634 rs11717836 chr3:52807736 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.9 -0.4 2.9e-6 Bipolar disorder; TGCT cis rs10089 1.000 rs62373701 chr5:127416294 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.81 7.57 0.56 7.27e-12 Ileal carcinoids; TGCT cis rs2404602 0.684 rs8029283 chr15:76837140 A/G cg23625390 chr15:77176239 SCAPER -0.38 -4.68 -0.39 7.3e-6 Blood metabolite levels; TGCT cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.12 -0.42 1.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg20607798 chr8:58055168 NA 0.45 4.6 0.38 1.05e-5 Developmental language disorder (linguistic errors); TGCT cis rs6460942 0.841 rs17443848 chr7:12443688 A/G cg06484146 chr7:12443880 VWDE -0.54 -5.76 -0.46 6.25e-8 Coronary artery disease; TGCT cis rs11718455 0.767 rs11708363 chr3:43966585 G/A cg08738300 chr3:44038990 NA 0.75 5.71 0.46 7.9e-8 Coronary artery disease; TGCT cis rs35883536 0.514 rs4908062 chr1:101013211 T/C cg10298815 chr1:101004474 GPR88 0.24 4.6 0.38 1.01e-5 Monocyte count; TGCT cis rs478607 0.915 rs61884449 chr11:64485193 C/T cg19395706 chr11:64412079 NRXN2 0.54 5.67 0.45 9.56e-8 Urate levels; TGCT cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs2404602 0.735 rs11635463 chr15:76762986 C/T cg22467129 chr15:76604101 ETFA 0.48 5.11 0.42 1.16e-6 Blood metabolite levels; TGCT cis rs902774 0.515 rs2363635 chr12:53354622 T/C cg25025879 chr12:53359317 NA -0.45 -5.01 -0.41 1.82e-6 Prostate cancer; TGCT cis rs13191362 1.000 rs34725898 chr6:163127302 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.16 9.92 0.67 1.96e-17 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11711311 0.911 rs28577577 chr3:113447276 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -7.13 -0.54 7.14e-11 IgG glycosylation; TGCT cis rs5769765 0.913 rs4824111 chr22:50284305 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.18 13.09 0.76 4.1e-25 Schizophrenia; TGCT cis rs17376456 0.825 rs74825443 chr5:93254973 T/C cg21475434 chr5:93447410 FAM172A 0.65 4.5 0.37 1.57e-5 Diabetic retinopathy; TGCT cis rs6582630 0.519 rs12578283 chr12:38325349 A/T cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs10504229 1.000 rs6987435 chr8:58177334 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs3008870 1.000 rs7511948 chr1:67430427 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs769267 0.965 rs2965198 chr19:19473030 A/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.68 -5.57 -0.45 1.51e-7 Tonsillectomy; TGCT cis rs9549260 0.785 rs6563842 chr13:41244297 G/T cg21288729 chr13:41239152 FOXO1 1.0 10.25 0.68 3.06e-18 Red blood cell count; TGCT cis rs5760092 0.755 rs3884794 chr22:24251766 C/A cg00024416 chr22:24240387 NA -0.34 -5.91 -0.47 3.02e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs8180040 0.620 rs11715121 chr3:47072621 T/A cg27129171 chr3:47204927 SETD2 -0.71 -8.51 -0.61 4.8e-14 Colorectal cancer; TGCT cis rs875971 1.000 rs10257427 chr7:65743208 T/C cg18876405 chr7:65276391 NA -0.34 -5.08 -0.41 1.38e-6 Aortic root size; TGCT cis rs1005277 0.557 rs176887 chr10:38406094 T/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs7843479 0.601 rs7220 chr8:21863290 G/A cg17168535 chr8:21777572 XPO7 0.8 8.16 0.59 3.19e-13 Mean corpuscular volume; TGCT cis rs7954584 0.531 rs11043271 chr12:122394921 A/C cg21171335 chr12:122356390 WDR66 0.7 6.99 0.53 1.46e-10 Mean corpuscular volume; TGCT cis rs6076065 0.594 rs6048755 chr20:23337233 A/G cg11657817 chr20:23433608 CST11 0.31 5.35 0.43 4.06e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs2721195 0.549 rs2958492 chr8:145919126 C/T cg15320075 chr8:145703422 NA 0.49 4.61 0.38 9.86e-6 Age at first birth; TGCT cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg02725872 chr8:58115012 NA -0.4 -4.86 -0.4 3.52e-6 Developmental language disorder (linguistic errors); TGCT cis rs2594989 0.565 rs62245958 chr3:11601493 C/G cg00170343 chr3:11313890 ATG7 -0.64 -4.8 -0.4 4.57e-6 Circulating chemerin levels; TGCT cis rs7666738 0.791 rs13127542 chr4:98949159 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs56309584 0.523 rs3027172 chr17:8055723 A/G cg08322244 chr17:8066669 VAMP2 -0.52 -4.71 -0.39 6.61e-6 Initial pursuit acceleration; TGCT cis rs1150668 0.796 rs1052215 chr6:28348158 T/G cg19488431 chr6:28601329 NA -0.2 -4.52 -0.38 1.42e-5 Pubertal anthropometrics; TGCT cis rs9807989 0.765 rs6751967 chr2:102967413 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs78487399 0.808 rs6544666 chr2:43732234 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.82 -0.4 4.03e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1055129 0.655 rs3744006 chr17:73838816 G/A cg08125733 chr17:73851984 WBP2 0.58 5.12 0.42 1.12e-6 White matter hyperintensity burden; TGCT cis rs651907 0.535 rs12633089 chr3:101528763 C/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.52 -0.51 1.56e-9 Colorectal cancer; TGCT cis rs7811142 1.000 rs112317829 chr7:100043173 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs1949733 0.848 rs2255501 chr4:8475014 G/A cg11789530 chr4:8429930 ACOX3 -0.58 -5.19 -0.42 8.5e-7 Response to antineoplastic agents; TGCT cis rs3824867 0.920 rs7130693 chr11:47452321 T/C cg20307385 chr11:47447363 PSMC3 -0.69 -5.86 -0.47 3.99e-8 Mean corpuscular hemoglobin; TGCT cis rs704795 0.867 rs7566052 chr2:27628635 A/G cg12000995 chr2:27665139 KRTCAP3 -0.35 -4.46 -0.37 1.84e-5 Menopause (age at onset); TGCT cis rs12479064 0.724 rs2309618 chr2:99974473 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.57 -4.47 -0.37 1.71e-5 Chronic sinus infection; TGCT cis rs6701037 0.566 rs729675 chr1:175136946 T/C cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs28386778 0.966 rs2854161 chr17:61976093 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.51 -4.49 -0.37 1.62e-5 Prudent dietary pattern; TGCT cis rs597539 0.652 rs686390 chr11:68656077 T/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.01 0.58 7.13e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4654899 0.643 rs12123092 chr1:21067001 A/G cg01072550 chr1:21505969 NA 0.44 6.88 0.53 2.68e-10 Superior frontal gyrus grey matter volume; TGCT cis rs902774 0.554 rs4919749 chr12:53358034 C/T cg14581129 chr12:53358946 NA -0.56 -6.32 -0.49 4.32e-9 Prostate cancer; TGCT trans rs10506458 0.834 rs73125186 chr12:63373400 C/T cg22491629 chr6:157744540 C6orf35 -0.96 -8.25 -0.6 2.01e-13 Hemostatic factors and hematological phenotypes; TGCT cis rs709400 0.633 rs3783395 chr14:103895020 T/C cg12935359 chr14:103987150 CKB -0.35 -5.28 -0.43 5.66e-7 Body mass index; TGCT cis rs10191773 0.535 rs11685514 chr2:113100014 C/T cg07905836 chr2:113190072 RGPD8;RGPD5 0.47 5.03 0.41 1.67e-6 Yeast infection; TGCT cis rs9397585 0.626 rs6932847 chr6:153448307 G/A cg24028809 chr6:153414101 RGS17 0.22 4.66 0.39 8.15e-6 Body mass index; TGCT trans rs916888 0.610 rs199438 chr17:44791643 G/A cg22968622 chr17:43663579 NA 0.98 9.28 0.64 7.03e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg03806693 chr22:41940476 POLR3H 1.12 13.0 0.76 6.57e-25 Vitiligo; TGCT trans rs629535 0.679 rs62511660 chr8:70157089 G/A cg21567404 chr3:27674614 NA -0.51 -7.72 -0.57 3.4e-12 Dupuytren's disease; TGCT cis rs72945132 0.882 rs56368190 chr11:70204328 T/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9653442 0.545 rs13415465 chr2:100764004 T/G cg22139774 chr2:100720529 AFF3 -0.36 -5.72 -0.46 7.68e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3096299 0.692 rs4785565 chr16:89515759 T/C cg06640241 chr16:89574553 SPG7 0.75 8.35 0.6 1.12e-13 Multiple myeloma (IgH translocation); TGCT cis rs6912958 0.781 rs9444504 chr6:88181046 A/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.18 -0.42 8.55e-7 Monocyte percentage of white cells; TGCT cis rs3824867 0.881 rs4752829 chr11:47396654 G/A cg20307385 chr11:47447363 PSMC3 -0.65 -5.44 -0.44 2.73e-7 Mean corpuscular hemoglobin; TGCT cis rs4654899 0.897 rs10916856 chr1:21082074 A/C cg01072550 chr1:21505969 NA -0.49 -7.93 -0.58 1.12e-12 Superior frontal gyrus grey matter volume; TGCT cis rs4819052 0.851 rs2838850 chr21:46671445 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3617 0.573 rs6795646 chr3:52922621 C/T cg10802521 chr3:52805072 NEK4 0.56 6.23 0.49 6.81e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7192750 0.562 rs9889011 chr16:71987816 T/A cg06353428 chr16:71660113 MARVELD3 0.74 6.6 0.51 1.09e-9 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7819412 0.618 rs34772085 chr8:10964906 C/T cg12940923 chr8:10282607 MSRA -0.18 -4.5 -0.37 1.55e-5 Triglycerides; TGCT cis rs9858542 1.000 rs2172252 chr3:49678307 A/T cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs832540 0.629 rs10461616 chr5:56080347 T/C cg24531977 chr5:56204891 C5orf35 -0.5 -5.08 -0.42 1.34e-6 Coronary artery disease; TGCT cis rs2033711 0.936 rs893185 chr19:58989495 A/C cg13877915 chr19:58951672 ZNF132 0.82 8.77 0.62 1.17e-14 Uric acid clearance; TGCT cis rs7226408 0.894 rs72885212 chr18:34399131 G/A cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs589448 0.872 rs315111 chr12:69784695 G/A cg11871910 chr12:69753446 YEATS4 0.89 10.53 0.69 6.39e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs929354 0.772 rs7778193 chr7:156980087 C/T cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs25422 0.878 rs55894300 chr6:118982076 T/A cg07617317 chr6:118971624 C6orf204 0.49 5.15 0.42 9.91e-7 Renal cell carcinoma; TGCT trans rs1814175 0.791 rs10769625 chr11:49869887 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs9311474 0.508 rs11720243 chr3:52618018 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.09 -0.42 1.29e-6 Electroencephalogram traits; TGCT cis rs634534 0.562 rs661335 chr11:65754061 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.65 6.38 0.5 3.14e-9 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs11030122 0.702 rs7128762 chr11:3943277 C/G cg18678763 chr11:4115507 RRM1 -0.49 -6.14 -0.48 1.01e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs3785574 0.962 rs7215915 chr17:61828385 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.58 5.24 0.43 6.6e-7 Height; TGCT cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs2836974 0.931 rs13047663 chr21:40708818 C/T cg06238570 chr21:40685208 BRWD1 0.61 5.06 0.41 1.46e-6 Cognitive function; TGCT cis rs1563304 1 rs1563304 chr17:44874453 C/T cg15921436 chr17:44337874 NA 0.46 5.28 0.43 5.65e-7 Neuroticism; TGCT cis rs700651 0.789 rs10497812 chr2:198911245 A/G cg00792783 chr2:198669748 PLCL1 -0.6 -5.2 -0.42 8.05e-7 Intracranial aneurysm; TGCT cis rs9291683 0.526 rs12506122 chr4:10033538 C/A cg00071950 chr4:10020882 SLC2A9 0.6 6.93 0.53 2.08e-10 Bone mineral density; TGCT cis rs7264396 0.836 rs6058282 chr20:34212590 T/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -4.82 -0.4 4.17e-6 Total cholesterol levels; TGCT cis rs138249 0.966 rs138238 chr22:50563140 T/C cg24864161 chr22:50528282 MOV10L1 0.47 4.78 0.39 4.9100000000000004e-06 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs34779708 0.931 rs17591135 chr10:35465190 T/A cg03585969 chr10:35415529 CREM 0.43 4.52 0.38 1.4e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs1692580 0.807 rs4648628 chr1:2203490 C/T cg24578937 chr1:2090814 PRKCZ 0.21 4.58 0.38 1.13e-5 Coronary artery disease; TGCT cis rs896854 0.625 rs4735336 chr8:95973410 A/C cg09323728 chr8:95962352 TP53INP1 0.48 6.18 0.49 8.33e-9 Type 2 diabetes; TGCT cis rs453301 0.686 rs6601280 chr8:8909236 A/T cg15556689 chr8:8085844 FLJ10661 0.66 5.67 0.45 9.32e-8 Joint mobility (Beighton score); TGCT cis rs42648 0.837 rs6970750 chr7:89938191 G/A cg25739043 chr7:89950458 NA -0.71 -7.18 -0.54 5.5e-11 Homocysteine levels; TGCT cis rs1008375 1.000 rs6846238 chr4:17629939 A/G cg10189774 chr4:17578691 LAP3 0.59 5.13 0.42 1.06e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9911578 0.933 rs11868348 chr17:57179238 C/T cg05425664 chr17:57184151 TRIM37 -0.68 -6.9 -0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs1865760 0.566 rs9467663 chr6:26021456 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.8 7.57 0.56 7.45e-12 Height; TGCT cis rs11190604 0.513 rs2489003 chr10:102360855 A/G cg16342193 chr10:102329863 NA -0.46 -5.15 -0.42 1.02e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs875971 1.000 rs1144895 chr7:65541307 C/G cg11764359 chr7:65958608 NA -0.56 -4.7 -0.39 6.74e-6 Aortic root size; TGCT cis rs4494114 0.967 rs11211566 chr1:39354700 G/C cg25970120 chr1:39325951 RRAGC -0.6 -6.19 -0.49 8.1e-9 Blood protein levels; TGCT cis rs10946940 0.965 rs6456799 chr6:27573536 A/G cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.73 -0.39 5.93e-6 Systemic lupus erythematosus; TGCT cis rs7429990 0.965 rs2882668 chr3:47980306 A/G cg11946769 chr3:48343235 NME6 0.53 4.48 0.37 1.65e-5 Educational attainment (years of education); TGCT cis rs2243480 1.000 rs1167613 chr7:65487439 C/T cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs922182 0.557 rs730589 chr15:64194173 G/T cg02919090 chr15:64263738 DAPK2 0.33 5.92 0.47 2.97e-8 Blood protein levels; TGCT trans rs2469997 1.000 rs2447172 chr8:120360863 A/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs13256369 0.756 rs13280759 chr8:8562995 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs2120019 1.000 rs12324912 chr15:75361006 G/A cg17294928 chr15:75287854 SCAMP5 -0.84 -6.34 -0.5 3.8e-9 Blood trace element (Zn levels); TGCT cis rs7666738 0.830 rs13129479 chr4:98987860 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs826838 1.000 rs1843881 chr12:38733706 A/G cg13010199 chr12:38710504 ALG10B -0.8 -6.55 -0.51 1.37e-9 Heart rate; TGCT trans rs9985766 1.000 rs9968348 chr4:151022142 G/A cg02993991 chr19:4064177 ZBTB7A 0.57 6.7 0.52 6.59e-10 Coronary artery disease;Myocardial infarction; TGCT cis rs832540 0.966 rs252925 chr5:56203773 G/A cg12311346 chr5:56204834 C5orf35 -0.49 -5.24 -0.43 6.72e-7 Coronary artery disease; TGCT cis rs11673344 0.504 rs4806407 chr19:37588751 A/G cg08039142 chr19:36980659 ZNF566 -0.53 -4.84 -0.4 3.84e-6 Obesity-related traits; TGCT cis rs231513 0.822 rs53907 chr17:41950810 C/A cg26893861 chr17:41843967 DUSP3 -0.8 -5.9 -0.47 3.3e-8 Cognitive function; TGCT cis rs854765 0.724 rs62072049 chr17:17906520 T/C cg09796270 chr17:17721594 SREBF1 0.27 5.4 0.44 3.22e-7 Total body bone mineral density; TGCT cis rs7772486 0.597 rs2246132 chr6:146182515 C/G cg05347473 chr6:146136440 FBXO30 0.66 6.24 0.49 6.34e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs910316 0.967 rs4899550 chr14:75647666 C/T cg23033748 chr14:75592666 NEK9 -0.29 -4.93 -0.41 2.55e-6 Height; TGCT cis rs727505 0.754 rs56012154 chr7:124781250 A/G cg23710748 chr7:124431027 NA -0.25 -4.44 -0.37 1.97e-5 Lewy body disease; TGCT cis rs13118159 0.934 rs2878608 chr4:1354286 C/G cg22683308 chr4:1340831 KIAA1530 -0.59 -5.69 -0.46 8.47e-8 Longevity; TGCT cis rs3125734 0.582 rs7904465 chr10:64002393 G/A cg05499367 chr10:63213510 TMEM26 -0.33 -4.44 -0.37 1.96e-5 Rheumatoid arthritis; TGCT cis rs1341267 0.529 rs6492720 chr13:95256305 T/C cg18412871 chr13:95254051 GPR180 -0.62 -5.45 -0.44 2.58e-7 Triglyceride levels; TGCT cis rs6429082 0.791 rs291394 chr1:235651682 A/G cg26050004 chr1:235667680 B3GALNT2 0.59 5.26 0.43 6.02e-7 Adiposity; TGCT cis rs2836974 0.533 rs418298 chr21:40536654 A/T cg17971929 chr21:40555470 PSMG1 0.7 6.39 0.5 2.97e-9 Cognitive function; TGCT cis rs739496 0.579 rs12313385 chr12:112292147 C/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs78487399 0.808 rs13431070 chr2:43721954 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.44 5.77 0.46 6.09e-8 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7617773 0.780 rs34946886 chr3:48338487 A/G cg11946769 chr3:48343235 NME6 0.82 7.06 0.54 1.03e-10 Coronary artery disease; TGCT cis rs317689 0.690 rs10878946 chr12:69642315 C/T cg14784868 chr12:69753453 YEATS4 0.54 4.5 0.37 1.56e-5 Response to diuretic therapy; TGCT cis rs546131 0.928 rs550313 chr11:34830919 C/T cg11058730 chr11:34937778 PDHX;APIP 0.58 5.12 0.42 1.16e-6 Lung disease severity in cystic fibrosis; TGCT cis rs2932538 0.922 rs112363416 chr1:113107543 T/C cg22162597 chr1:113214053 CAPZA1 0.28 5.83 0.46 4.4e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs208515 0.525 rs10498841 chr6:66663706 C/T cg07460842 chr6:66804631 NA 0.85 8.73 0.62 1.41e-14 Exhaled nitric oxide levels; TGCT cis rs7666738 0.830 rs1593572 chr4:98979322 A/G cg17366294 chr4:99064904 C4orf37 -0.63 -6.32 -0.49 4.34e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7819412 0.502 rs4840548 chr8:10992883 C/T cg21775007 chr8:11205619 TDH -0.56 -4.95 -0.41 2.34e-6 Triglycerides; TGCT cis rs12541335 0.639 rs7003478 chr8:22201123 A/G cg26039829 chr8:22132926 PIWIL2 0.27 5.13 0.42 1.1e-6 Hypertriglyceridemia; TGCT cis rs4253772 0.530 rs6008774 chr22:46755298 C/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.64 4.8 0.4 4.57e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs2562456 1.000 rs2562456 chr19:21666210 A/G cg25650185 chr19:21324782 ZNF431 -0.56 -4.83 -0.4 4.02e-6 Pain; TGCT cis rs4862750 0.872 rs4862747 chr4:187877236 A/T cg11301795 chr4:187892539 NA 0.31 4.76 0.39 5.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9660180 0.967 rs2272908 chr1:1721479 A/G cg20999797 chr1:1681921 NA -0.18 -4.81 -0.4 4.38e-6 Body mass index; TGCT cis rs73058052 0.597 rs7251877 chr19:50097547 A/G cg09250473 chr19:50168907 IRF3;BCL2L12 0.65 5.22 0.42 7.33e-7 Fibrinogen levels; TGCT cis rs2742417 1.000 rs2673057 chr3:45735730 A/T cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.14e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2334880 0.678 rs12918320 chr16:71463602 A/G cg06353428 chr16:71660113 MARVELD3 -1.16 -7.18 -0.54 5.59e-11 Malaria; TGCT cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs9916302 0.706 rs11657153 chr17:37699729 A/G cg07936489 chr17:37558343 FBXL20 -0.84 -6.16 -0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs2439831 0.681 rs528517 chr15:43612925 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.69 0.62 1.84e-14 Lung cancer in ever smokers; TGCT cis rs3935685 0.874 rs12911718 chr15:78004325 G/A cg03457338 chr15:78040120 NA -0.22 -5.73 -0.46 7.26e-8 Intelligence (multi-trait analysis); TGCT cis rs9341808 0.714 rs9448911 chr6:80913859 A/G cg08355045 chr6:80787529 NA 0.31 5.1 0.42 1.26e-6 Sitting height ratio; TGCT cis rs13242816 1.000 rs7809755 chr7:116110732 C/T cg02799643 chr7:116139180 CAV2 -0.48 -5.52 -0.44 1.87e-7 P wave duration; TGCT cis rs8017423 0.967 rs12589808 chr14:90719236 C/T cg04374321 chr14:90722782 PSMC1 -0.74 -7.35 -0.55 2.38e-11 Mortality in heart failure; TGCT cis rs5769707 0.967 rs5770585 chr22:50007874 G/A cg05373962 chr22:49881684 NA -0.3 -6.19 -0.49 8.01e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9399135 0.967 rs13218642 chr6:135309940 A/G cg24558204 chr6:135376177 HBS1L 0.48 4.75 0.39 5.5e-6 Red blood cell count; TGCT cis rs9527 0.590 rs3781282 chr10:104852419 C/T cg04362960 chr10:104952993 NT5C2 -0.72 -6.18 -0.49 8.27e-9 Arsenic metabolism; TGCT cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs904251 0.525 rs12200378 chr6:37425304 A/G cg25019722 chr6:37503610 NA -0.48 -6.96 -0.53 1.72e-10 Cognitive performance; TGCT cis rs2455799 0.573 rs2062824 chr3:15757901 T/C cg16303742 chr3:15540471 COLQ -0.26 -5.08 -0.41 1.37e-6 Mean platelet volume; TGCT cis rs4285028 0.948 rs7615571 chr3:121665950 A/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs611744 0.669 rs13251024 chr8:109258333 T/C cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs9611565 0.921 rs5751081 chr22:41742788 A/T cg13695892 chr22:41940480 POLR3H -0.72 -7.37 -0.55 2.15e-11 Vitiligo; TGCT cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.57 4.85 0.4 3.59e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs617219 0.726 rs955897 chr5:78431486 A/C cg23987322 chr5:78407566 BHMT 0.35 4.56 0.38 1.22e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10504229 0.683 rs67048677 chr8:58140023 C/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs36051895 0.695 rs10123976 chr9:4997333 A/T cg02405213 chr9:5042618 JAK2 -0.73 -9.48 -0.65 2.27e-16 Pediatric autoimmune diseases; TGCT cis rs1577917 1.000 rs34622557 chr6:86630852 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg03806693 chr22:41940476 POLR3H 1.13 12.99 0.76 6.98e-25 Vitiligo; TGCT cis rs4766566 0.590 rs3809283 chr12:111707754 A/T cg10833066 chr12:111807467 FAM109A 0.33 4.65 0.39 8.5e-6 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs137603 0.933 rs137591 chr22:39685450 A/G cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -5.02 -0.41 1.78e-6 Primary biliary cholangitis; TGCT cis rs2074585 0.647 rs2589961 chr15:90916840 G/A cg22089800 chr15:90895588 ZNF774 0.82 9.04 0.63 2.58e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs1670533 1.000 rs6852850 chr4:1052857 C/G cg27284194 chr4:1044797 NA 0.67 5.77 0.46 5.9e-8 Recombination rate (females); TGCT cis rs2840044 1.000 rs8073935 chr17:33985849 C/T cg05299278 chr17:33885742 SLFN14 0.22 4.98 0.41 2.07e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs9457247 0.534 rs9366078 chr6:167399512 A/G cg23791538 chr6:167370224 RNASET2 0.61 6.02 0.48 1.85e-8 Crohn's disease; TGCT cis rs769267 0.899 rs67720221 chr19:19440864 C/T cg02546618 chr19:19431379 KIAA0892;SF4 -0.6 -4.96 -0.41 2.26e-6 Tonsillectomy; TGCT cis rs79349575 0.715 rs999474 chr17:46987665 G/A cg07967210 chr17:47022446 SNF8 -0.41 -5.44 -0.44 2.69e-7 Type 2 diabetes; TGCT cis rs7027203 0.595 rs4308796 chr9:96570165 G/A cg14598338 chr9:96623480 NA 0.52 7.48 0.56 1.16e-11 DNA methylation (variation); TGCT cis rs6582630 0.555 rs7305352 chr12:38473800 T/C cg13010199 chr12:38710504 ALG10B 0.64 5.09 0.42 1.27e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs6565180 0.888 rs11150586 chr16:30420851 T/C cg17640201 chr16:30407289 ZNF48 0.92 8.66 0.61 2.06e-14 Tonsillectomy; TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.94 -0.41 2.48e-6 Prudent dietary pattern; TGCT cis rs1153858 1.000 rs2668747 chr15:45617216 T/C cg14582100 chr15:45693742 SPATA5L1 0.46 5.44 0.44 2.73e-7 Homoarginine levels; TGCT cis rs13096760 1 rs13096760 chr3:49476806 T/C cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs118119933 chr7:99939050 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.99 6.93 0.53 2.02e-10 Platelet count; TGCT cis rs4285028 0.699 rs7637495 chr3:121573850 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.78 -6.72 -0.52 5.95e-10 Multiple sclerosis; TGCT cis rs7267979 0.744 rs6050463 chr20:25208990 G/A cg16686733 chr20:25566563 NINL 0.48 4.51 0.38 1.5e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8078723 0.738 rs4065321 chr17:38143548 C/T cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.69e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs1322512 0.677 rs2695251 chr6:152927101 T/C cg03415253 chr6:152958462 SYNE1 -0.55 -5.2 -0.42 8.12e-7 Tonometry; TGCT trans rs7618501 1.000 rs7634902 chr3:49762662 G/T cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs9311474 0.508 rs1570 chr3:52586682 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.1 -0.42 1.22e-6 Electroencephalogram traits; TGCT cis rs711245 0.637 rs6729495 chr2:36834192 T/A cg15105969 chr2:36825350 FEZ2 0.62 6.06 0.48 1.49e-8 Height; TGCT cis rs931127 0.747 rs11820062 chr11:65429936 T/C cg27068330 chr11:65405492 SIPA1 -0.62 -6.12 -0.48 1.16e-8 Systemic lupus erythematosus; TGCT cis rs1577917 0.771 rs2475790 chr6:86368068 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs72949976 0.646 rs11681232 chr2:214033002 G/A cg08319019 chr2:214017104 IKZF2 0.87 8.64 0.61 2.37e-14 Lung cancer;Squamous cell lung carcinoma; TGCT cis rs3812831 0.599 rs428636 chr13:114927133 T/C cg06611532 chr13:114900021 NA 0.35 6.39 0.5 3.1e-9 Schizophrenia; TGCT cis rs1552244 0.572 rs41464050 chr3:10158393 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.61 0.45 1.27e-7 Alzheimer's disease; TGCT cis rs7208859 0.623 rs1054400 chr17:29109954 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.83 0.4 3.98e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs889312 0.500 rs252906 chr5:56119190 G/T cg12311346 chr5:56204834 C5orf35 -0.45 -4.87 -0.4 3.28e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs67311347 1.000 rs6801859 chr3:40493218 G/T cg13683864 chr3:40499215 RPL14 1.12 11.95 0.73 2.27e-22 Renal cell carcinoma; TGCT cis rs7772486 0.905 rs9373486 chr6:146446024 C/G cg23711669 chr6:146136114 FBXO30 -0.86 -9.69 -0.66 7.19e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.671 rs2591961 chr5:56238597 A/G cg12311346 chr5:56204834 C5orf35 0.58 6.19 0.49 7.92e-9 Initial pursuit acceleration; TGCT cis rs921968 0.541 rs585185 chr2:219457741 G/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs4851266 0.966 rs13018640 chr2:100821545 T/C cg22139774 chr2:100720529 AFF3 -0.36 -5.4 -0.44 3.26e-7 Educational attainment; TGCT cis rs7010267 0.623 rs13254554 chr8:120010805 T/C cg17171407 chr8:119960777 TNFRSF11B 0.27 4.94 0.41 2.49e-6 Total body bone mineral density (age 45-60); TGCT cis rs11098499 0.863 rs1552095 chr4:120460306 A/G cg09307838 chr4:120376055 NA 0.71 6.69 0.52 6.71e-10 Corneal astigmatism; TGCT cis rs2204008 0.837 rs12581130 chr12:38319387 A/G cg26384229 chr12:38710491 ALG10B 0.79 6.97 0.53 1.67e-10 Bladder cancer; TGCT cis rs9486715 0.838 rs6928442 chr6:96870118 A/G cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs7666738 1.000 rs880473 chr4:98922596 C/T cg05340658 chr4:99064831 C4orf37 0.51 5.0 0.41 1.88e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs74233809 1.000 rs2297787 chr10:104680137 T/A cg05855489 chr10:104503620 C10orf26 0.77 4.49 0.37 1.61e-5 Birth weight; TGCT cis rs6089829 0.888 rs4809467 chr20:61671688 A/G cg08045932 chr20:61659980 NA 0.5 8.69 0.62 1.75e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs7399018 0.739 rs7953955 chr12:51608467 A/G cg25754956 chr12:51612065 POU6F1 0.96 10.38 0.68 1.47e-18 Cisplatin-induced ototoxicity; TGCT cis rs3806843 1.000 rs2240694 chr5:140183058 G/A cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6840360 0.615 rs4696268 chr4:152464723 G/A cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs7940866 0.801 rs10894300 chr11:130845943 A/G cg12179176 chr11:130786555 SNX19 0.62 5.95 0.47 2.57e-8 Schizophrenia; TGCT cis rs13177918 0.677 rs13161417 chr5:149822500 G/C cg14059543 chr5:149831962 NA -0.71 -9.46 -0.65 2.58e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs735396 0.731 rs1182933 chr12:121454622 C/T cg15155738 chr12:121454335 C12orf43 0.54 4.74 0.39 5.81e-6 N-glycan levels; TGCT cis rs11148252 0.574 rs9536247 chr13:53279542 T/C cg02158880 chr13:53174818 NA 0.4 4.84 0.4 3.7e-6 Lewy body disease; TGCT cis rs8177253 0.665 rs4525863 chr3:133436136 C/A cg08048268 chr3:133502702 NA -0.54 -7.11 -0.54 8.1e-11 Iron status biomarkers; TGCT cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg21724239 chr8:58056113 NA 0.47 5.05 0.41 1.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.791 rs2903142 chr4:99040071 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9644630 0.672 rs12542081 chr8:19317786 G/T cg06699216 chr8:19333253 CSGALNACT1 -0.27 -4.77 -0.39 5.04e-6 Oropharynx cancer; TGCT cis rs4499344 0.805 rs12978075 chr19:33067852 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.7 -6.18 -0.49 8.37e-9 Mean platelet volume; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs6762 0.748 rs7936838 chr11:839093 G/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.47 -4.65 -0.39 8.32e-6 Mean platelet volume; TGCT cis rs6088580 0.634 rs6141471 chr20:33006730 A/G cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs9611565 0.694 rs202628 chr22:41849513 A/G cg06481639 chr22:41940642 POLR3H -0.69 -5.92 -0.47 2.95e-8 Vitiligo; TGCT cis rs7267979 1.000 rs2259873 chr20:25280781 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs709400 0.663 rs1028613 chr14:103888324 G/A cg26031613 chr14:104095156 KLC1 0.86 9.43 0.65 2.96e-16 Body mass index; TGCT cis rs11792861 0.816 rs11790105 chr9:111731785 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 4.9 0.4 2.93e-6 Menarche (age at onset); TGCT cis rs910316 0.699 rs175039 chr14:75468950 G/C cg11812906 chr14:75593930 NEK9 -0.59 -5.59 -0.45 1.37e-7 Height; TGCT cis rs5750830 0.569 rs5750809 chr22:39791491 T/G cg11247378 chr22:39784982 NA -0.74 -9.64 -0.65 9.38e-17 Intelligence (multi-trait analysis); TGCT cis rs8176704 0.702 rs11244086 chr9:136191787 A/G cg14012599 chr9:136805113 VAV2 0.33 4.6 0.38 1.01e-5 Coagulation factor levels;Low vWF levels; TGCT cis rs10504229 1.000 rs59275611 chr8:58195191 G/A cg22535103 chr8:58192502 C8orf71 -0.39 -4.6 -0.38 1.01e-5 Developmental language disorder (linguistic errors); TGCT cis rs7552404 0.883 rs7513363 chr1:76143443 A/G cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13256369 1.000 rs9329166 chr8:8576655 C/T cg18904891 chr8:8559673 CLDN23 0.63 6.12 0.48 1.13e-8 Obesity-related traits; TGCT cis rs2463822 1.000 rs7481995 chr11:62129312 G/C cg23876832 chr11:62092739 NA 0.64 4.72 0.39 6.28e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9486715 1.000 rs11153082 chr6:97059666 A/G cg18709589 chr6:96969512 KIAA0776 -0.81 -7.71 -0.57 3.5e-12 Headache; TGCT cis rs28386778 1.000 rs28386778 chr17:61964815 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.7 0.39 6.81e-6 Prudent dietary pattern; TGCT cis rs4820539 0.966 rs5751587 chr22:23470090 G/A cg21100191 chr22:23484243 RTDR1 0.89 10.61 0.69 4.23e-19 Bone mineral density; TGCT cis rs1129187 0.967 rs9462857 chr6:42943098 T/C cg18735214 chr6:43276756 CRIP3 -0.56 -4.84 -0.4 3.76e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs1505368 0.532 rs2888093 chr2:213328348 G/A cg16329650 chr2:213403929 ERBB4 0.84 9.7 0.66 6.76e-17 Symmetrical dimethylarginine levels; TGCT cis rs2204008 0.805 rs3863360 chr12:37966432 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.56e-12 Bladder cancer; TGCT cis rs6700896 0.500 rs6690625 chr1:66077590 T/G cg14976592 chr1:65886160 LEPROT;LEPR 0.63 5.01 0.41 1.81e-6 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2230307 0.536 rs561119 chr1:100603891 G/A cg24955406 chr1:100503596 HIAT1 -0.73 -4.96 -0.41 2.27e-6 Carotid intima media thickness; TGCT cis rs597539 0.652 rs513615 chr11:68705504 G/T cg06112835 chr11:68658793 MRPL21 0.5 8.47 0.61 5.89e-14 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9611565 0.546 rs5758430 chr22:42109844 G/T cg06634786 chr22:41940651 POLR3H 0.89 9.09 0.63 1.96e-15 Vitiligo; TGCT cis rs9682041 0.825 rs6785326 chr3:170095145 T/C cg11886554 chr3:170076028 SKIL 0.83 6.42 0.5 2.66e-9 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs9653442 0.835 rs7565967 chr2:100744683 G/T cg22139774 chr2:100720529 AFF3 -0.44 -7.6 -0.56 6.3e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs11096990 0.613 rs6840578 chr4:39208616 A/G cg20847110 chr4:39482781 LOC401127 0.16 4.53 0.38 1.36e-5 Cognitive function; TGCT cis rs7000551 0.751 rs2443494 chr8:22372262 C/G cg12081754 chr8:22256438 SLC39A14 0.3 4.87 0.4 3.26e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg18538332 chr22:24372958 LOC391322 -0.87 -9.98 -0.67 1.39e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7208859 0.623 rs11658945 chr17:29122509 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12478296 0.792 rs3924263 chr2:243005167 A/C cg06360820 chr2:242988706 NA -0.64 -5.35 -0.43 4.15e-7 Obesity-related traits; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.51 5.71 0.46 7.95e-8 Lymphocyte counts; TGCT trans rs7819412 0.806 rs2409689 chr8:10932868 A/G cg06636001 chr8:8085503 FLJ10661 -0.77 -7.06 -0.54 1.06e-10 Triglycerides; TGCT cis rs1577917 1.000 rs12209127 chr6:86724427 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs11690935 0.959 rs6722757 chr2:172591963 A/G cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.51 -0.75 9.78e-24 Schizophrenia; TGCT cis rs1577917 0.958 rs13219504 chr6:86556917 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.65 -5.25 -0.43 6.3e-7 Response to antipsychotic treatment; TGCT cis rs4665630 0.522 rs114382704 chr2:23951810 G/T cg08063864 chr2:24346004 PFN4;LOC375190 1.19 5.14 0.42 1.06e-6 Hypertension; TGCT cis rs9394169 0.533 rs4713675 chr6:33718418 C/T cg13859433 chr6:33739653 LEMD2 -0.31 -5.19 -0.42 8.5e-7 Essential tremor; TGCT cis rs634534 0.561 rs613924 chr11:65769295 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.65 6.42 0.5 2.59e-9 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs2115630 0.902 rs8023276 chr15:85219638 C/T cg17173187 chr15:85201210 NMB -0.41 -5.2 -0.42 7.89e-7 P wave terminal force; TGCT cis rs12136530 0.774 rs12092284 chr1:19778323 C/T cg18923740 chr1:19971790 NBL1 0.37 4.55 0.38 1.27e-5 Lead levels in blood; TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg08736216 chr1:53307985 ZYG11A -0.25 -4.68 -0.39 7.33e-6 Monocyte count; TGCT cis rs6500602 0.627 rs709632 chr16:4587811 C/G cg14951292 chr16:4525986 HMOX2;NMRAL1 -0.4 -7.18 -0.54 5.64e-11 Schizophrenia; TGCT cis rs7659604 0.702 rs61217486 chr4:122693973 T/C cg06713675 chr4:122721982 EXOSC9 -0.57 -7.77 -0.57 2.59e-12 Type 2 diabetes; TGCT cis rs72781680 0.716 rs6718631 chr2:24036086 A/G cg08917208 chr2:24149416 ATAD2B -0.78 -4.85 -0.4 3.62e-6 Lymphocyte counts; TGCT cis rs2299587 0.560 rs7814692 chr8:17780157 G/A cg01800426 chr8:17659068 MTUS1 -0.71 -6.02 -0.48 1.8e-8 Economic and political preferences; TGCT cis rs1153858 1.000 rs1890565 chr15:45663299 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs17376456 1.000 rs17376456 chr5:93557702 C/T cg25358565 chr5:93447407 FAM172A -0.94 -7.79 -0.57 2.26e-12 Diabetic retinopathy; TGCT cis rs7666738 0.546 rs6827131 chr4:98744810 C/G cg05340658 chr4:99064831 C4orf37 0.52 5.76 0.46 6.27e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2535633 0.820 rs7626551 chr3:52938092 C/G cg11645453 chr3:52864694 ITIH4 -0.28 -5.37 -0.43 3.77e-7 Body mass index; TGCT cis rs3806843 1.000 rs10073974 chr5:140165231 T/C cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs5167 0.566 rs35080293 chr19:45496624 T/G cg09555818 chr19:45449301 APOC2 0.24 4.83 0.4 3.96e-6 Blood protein levels; TGCT cis rs6940638 0.956 rs10946899 chr6:27023694 T/A cg05738196 chr6:26577821 NA -0.5 -4.5 -0.37 1.52e-5 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs116305850 chr4:119779892 A/G cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs10858047 0.883 rs12039811 chr1:115107550 T/C cg12756093 chr1:115239321 AMPD1 0.47 4.96 0.41 2.27e-6 Autism; TGCT cis rs9952991 0.883 rs2542147 chr18:12775851 G/T cg23544223 chr18:12777786 NA 0.63 6.02 0.48 1.85e-8 Inflammatory skin disease; TGCT cis rs17376456 0.825 rs1470150 chr5:93138654 C/T cg21475434 chr5:93447410 FAM172A -0.63 -5.27 -0.43 5.89e-7 Diabetic retinopathy; TGCT cis rs1552244 0.572 rs3774208 chr3:10164722 T/G cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs2242116 0.743 rs11719795 chr3:46951935 T/C cg02527881 chr3:46936655 PTH1R -0.28 -5.05 -0.41 1.55e-6 Birth weight; TGCT cis rs7917772 0.636 rs4418737 chr10:104525123 A/G cg11453585 chr10:104263688 ACTR1A;SUFU -0.56 -4.59 -0.38 1.07e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4478858 0.735 rs3806255 chr1:31791578 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.94 -0.41 2.47e-6 Alcohol dependence; TGCT cis rs9653442 0.545 rs13415465 chr2:100764004 T/G cg07810366 chr2:100720526 AFF3 -0.36 -5.31 -0.43 4.89e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7818688 0.697 rs112076731 chr8:95978121 C/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs425277 0.585 rs364677 chr1:2071765 A/G cg24578937 chr1:2090814 PRKCZ -0.25 -6.39 -0.5 2.97e-9 Height; TGCT cis rs7027203 0.828 rs10821229 chr9:96595136 A/C cg14396892 chr9:96623032 NA -0.26 -5.46 -0.44 2.51e-7 DNA methylation (variation); TGCT cis rs9611565 0.649 rs4822050 chr22:42177453 C/G cg06481639 chr22:41940642 POLR3H -0.55 -4.71 -0.39 6.54e-6 Vitiligo; TGCT cis rs11958404 0.858 rs72818142 chr5:157474934 C/T cg05962755 chr5:157440814 NA 0.35 4.48 0.37 1.65e-5 IgG glycosylation; TGCT cis rs9291683 0.588 rs6844329 chr4:10018544 T/C cg11266682 chr4:10021025 SLC2A9 0.73 10.98 0.7 5.33e-20 Bone mineral density; TGCT cis rs9910055 0.529 rs228748 chr17:42174390 G/A cg13607699 chr17:42295918 UBTF -0.63 -5.26 -0.43 6.1e-7 Total body bone mineral density; TGCT cis rs17102423 0.788 rs61987428 chr14:65606156 T/C cg11161011 chr14:65562177 MAX -0.46 -6.06 -0.48 1.51e-8 Obesity-related traits; TGCT cis rs3733585 0.673 rs116046986 chr4:9957794 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.71 -0.57 3.55e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9467773 0.620 rs2451737 chr6:26619041 T/C cg15659132 chr6:26577336 NA 0.84 10.91 0.7 7.83e-20 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.720 rs6931553 chr6:146112348 T/C cg13319975 chr6:146136371 FBXO30 0.58 5.24 0.43 6.75e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.716 rs11097615 chr4:99092773 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.65 0.45 1.04e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs1499614 1.000 rs2659903 chr7:66180931 G/A cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs5769765 0.908 rs4824109 chr22:50271460 T/C cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs858239 0.796 rs433395 chr7:23401955 G/T cg05602783 chr7:23145260 KLHL7 -0.58 -4.75 -0.39 5.45e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7027203 0.797 rs57882762 chr9:96580825 T/G cg14396892 chr9:96623032 NA -0.3 -6.26 -0.49 5.85e-9 DNA methylation (variation); TGCT cis rs6951245 1.000 rs77346188 chr7:1114023 C/A cg27454412 chr7:1067447 C7orf50 0.58 4.54 0.38 1.3e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6690583 0.623 rs61768853 chr1:85455707 T/C cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg10862848 chr6:42927986 GNMT -0.38 -4.72 -0.39 6.35e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7267979 0.966 rs3827014 chr20:25371559 C/T cg14121845 chr20:25566513 NINL -0.5 -5.34 -0.43 4.25e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs873946 0.529 rs12258248 chr10:134573767 A/G cg18305652 chr10:134549665 INPP5A 0.31 5.3 0.43 5.01e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6121246 0.909 rs6087778 chr20:30354142 G/A cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs7020830 0.858 rs1492714 chr9:37141259 T/C cg14294708 chr9:37120828 ZCCHC7 1.31 20.37 0.88 2.24e-41 Schizophrenia; TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs7584330 0.737 rs10445707 chr2:238368751 A/G cg14458575 chr2:238380390 NA 0.51 8.25 0.6 1.91e-13 Prostate cancer; TGCT cis rs4455778 0.580 rs4268080 chr7:49117682 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7727544 0.606 rs11950562 chr5:131652529 A/C cg14196790 chr5:131705035 SLC22A5 0.35 4.83 0.4 3.96e-6 Blood metabolite levels; TGCT cis rs2836974 0.931 rs2836972 chr21:40652142 G/A cg11644478 chr21:40555479 PSMG1 1.02 11.05 0.7 3.46e-20 Cognitive function; TGCT cis rs7014346 0.740 rs4871788 chr8:128421785 G/A cg04263511 chr8:128962092 PVT1 -0.33 -4.71 -0.39 6.51e-6 Colorectal cancer; TGCT cis rs7085104 0.660 rs7902804 chr10:104585405 A/T cg15744005 chr10:104629667 AS3MT -0.42 -5.2 -0.42 8.04e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs17376456 0.877 rs13156865 chr5:93390908 C/A cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs6430585 0.528 rs309151 chr2:136661150 C/T cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg19723775 chr5:179050963 HNRNPH1 0.55 5.5 0.44 2.07e-7 Lung cancer; TGCT cis rs6138458 1.000 rs6138458 chr20:24973769 C/T cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs6582630 0.502 rs11520276 chr12:38359216 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.23 0.54 4.33e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg07061783 chr6:25882402 NA -0.84 -8.78 -0.62 1.1e-14 Intelligence (multi-trait analysis); TGCT cis rs1372520 0.684 rs356162 chr4:90697157 T/C cg15133208 chr4:90757351 SNCA 0.47 5.58 0.45 1.43e-7 Neuroticism; TGCT cis rs7176093 0.665 rs17581281 chr15:86386197 C/T cg22461649 chr15:86468928 NA -0.31 -5.28 -0.43 5.54e-7 Aging traits; TGCT cis rs10509586 0.522 rs1475274 chr10:91698909 A/G cg25278353 chr10:91717815 NA 0.43 5.13 0.42 1.08e-6 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy); TGCT cis rs7216064 0.953 rs58141639 chr17:65864902 C/T cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9914988 0.832 rs34901720 chr17:27179518 A/G cg20469991 chr17:27169893 C17orf63 -0.72 -4.8 -0.4 4.45e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9911578 0.904 rs7209253 chr17:56908987 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs250677 1.000 rs36080 chr5:148430451 A/G cg23229984 chr5:148520753 ABLIM3 0.21 4.97 0.41 2.18e-6 Breast cancer; TGCT cis rs9368481 0.761 rs9357030 chr6:26985026 G/T cg18867708 chr6:26865862 GUSBL1 -0.39 -5.16 -0.42 9.66e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 0.901 rs778730 chr7:65823325 T/A cg07424592 chr7:64974309 NA 1.27 7.29 0.55 3.13e-11 Diabetic kidney disease; TGCT cis rs597539 0.652 rs602364 chr11:68662167 C/T cg21963583 chr11:68658836 MRPL21 0.36 6.01 0.47 1.94e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7552404 0.731 rs12078299 chr1:76365764 T/A cg03433033 chr1:76189801 ACADM 0.74 7.01 0.53 1.34e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9911578 0.835 rs10853006 chr17:56489076 G/A cg05425664 chr17:57184151 TRIM37 0.61 5.68 0.45 9.14e-8 Intelligence (multi-trait analysis); TGCT cis rs2839186 0.619 rs2187118 chr21:47611310 C/T cg05896524 chr21:47604654 C21orf56 0.45 4.72 0.39 6.2e-6 Testicular germ cell tumor; TGCT cis rs11031096 0.502 rs4910875 chr11:4047855 C/G cg18678763 chr11:4115507 RRM1 -0.5 -6.18 -0.49 8.41e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9486719 1.000 rs2472882 chr6:96863474 C/T cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs11690935 0.959 rs2292815 chr2:172586651 C/G cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs1403694 0.695 rs3806689 chr3:186435077 A/G cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs7811142 0.830 rs6975660 chr7:99975266 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 7.8 0.57 2.16e-12 Platelet count; TGCT trans rs1973993 0.691 rs553785 chr1:96895325 G/A cg10631902 chr5:14652156 NA 0.4 10.92 0.7 7.19e-20 Weight; TGCT cis rs12579753 0.917 rs6539580 chr12:82184765 T/C cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs2486288 0.656 rs8024620 chr15:45574329 C/T cg26924012 chr15:45694286 SPATA5L1 -0.8 -8.41 -0.6 8.03e-14 Glomerular filtration rate; TGCT cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg08219700 chr8:58056026 NA 0.3 4.55 0.38 1.25e-5 Developmental language disorder (linguistic errors); TGCT cis rs2032447 0.670 rs198852 chr6:26104448 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.85 -9.0 -0.63 3.25e-15 Intelligence (multi-trait analysis); TGCT cis rs896854 0.654 rs4735340 chr8:95976251 A/T cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.59e-9 Type 2 diabetes; TGCT cis rs9787249 0.957 rs12239844 chr1:40217258 T/C cg20968010 chr1:40505947 CAP1 -0.52 -4.91 -0.4 2.79e-6 Blood protein levels; TGCT cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg03806693 chr22:41940476 POLR3H -1.13 -12.67 -0.75 4.12e-24 Vitiligo; TGCT cis rs10779751 0.770 rs2275527 chr1:11190646 A/G cg08854313 chr1:11322531 MTOR 0.82 6.59 0.51 1.11e-9 Body mass index; TGCT cis rs7169223 0.653 rs8042170 chr15:79096599 G/A cg21242079 chr15:79101063 ADAMTS7 0.3 4.99 0.41 1.98e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT trans rs6951245 0.507 rs11976805 chr7:1138716 C/T cg13565492 chr6:43139072 SRF -0.75 -7.01 -0.53 1.35e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2072499 0.865 rs2758608 chr1:156202860 A/T cg25208724 chr1:156163844 SLC25A44 0.97 10.22 0.68 3.76e-18 Testicular germ cell tumor; TGCT cis rs60871478 0.636 rs73045423 chr7:893952 G/A cg15782153 chr7:917662 C7orf20 0.54 4.92 0.4 2.74e-6 Cerebrospinal P-tau181p levels; TGCT cis rs11105298 0.786 rs10858867 chr12:89851166 C/T cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7666738 0.962 rs17550217 chr4:98999699 T/A cg05340658 chr4:99064831 C4orf37 0.46 4.59 0.38 1.09e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs7914558 0.966 rs10786745 chr10:104956827 A/G cg04362960 chr10:104952993 NT5C2 0.62 5.53 0.44 1.8e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs763014 0.932 rs2384975 chr16:651115 G/T cg00908189 chr16:619842 PIGQ 0.85 10.4 0.68 1.33e-18 Height; TGCT cis rs7647973 0.593 rs58339610 chr3:49845006 T/A cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.83 -0.4 3.96e-6 Menarche (age at onset); TGCT cis rs7829975 0.540 rs2976909 chr8:8346690 C/T cg15556689 chr8:8085844 FLJ10661 -0.53 -5.14 -0.42 1.05e-6 Mood instability; TGCT cis rs10992471 0.603 rs10118939 chr9:95293641 C/G cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.63 -0.45 1.13e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs42648 0.869 rs2027965 chr7:89912513 C/T cg25739043 chr7:89950458 NA -0.73 -7.31 -0.55 2.87e-11 Homocysteine levels; TGCT cis rs838147 0.537 rs504963 chr19:49208865 G/A cg13540341 chr19:49222985 MAMSTR -0.38 -5.0 -0.41 1.9e-6 Dietary macronutrient intake; TGCT cis rs12220898 0.749 rs4310533 chr10:50482625 C/G cg06072769 chr10:50146962 WDFY4 0.39 5.1 0.42 1.23e-6 Inflammatory biomarkers; TGCT cis rs478304 0.718 rs61744384 chr11:65387378 T/A cg17480646 chr11:65405466 SIPA1 -0.5 -6.09 -0.48 1.3e-8 Acne (severe); TGCT cis rs74233809 1.000 rs10883806 chr10:104713076 C/T cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs4665809 1.000 rs10048683 chr2:26320519 C/T cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs1453308 0.935 rs11692300 chr2:237179958 C/T cg19324714 chr2:237145437 ASB18 0.56 5.0 0.41 1.91e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs931608 1.000 rs11085534 chr19:22613229 A/G cg15554505 chr19:22123728 NA 0.55 4.54 0.38 1.32e-5 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs12477438 0.798 rs17708218 chr2:99696284 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.33 -0.49 4.01e-9 Chronic sinus infection; TGCT cis rs2404602 0.646 rs3764245 chr15:77223176 G/C cg23625390 chr15:77176239 SCAPER 0.39 4.96 0.41 2.24e-6 Blood metabolite levels; TGCT cis rs79057730 0.599 rs79272827 chr7:807015 C/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.65 6.11 0.48 1.17e-8 Initial pursuit acceleration; TGCT cis rs1150668 0.796 rs1052215 chr6:28348158 T/G cg13525197 chr6:28411240 ZSCAN23 0.5 4.87 0.4 3.34e-6 Pubertal anthropometrics; TGCT cis rs7772486 0.875 rs2224121 chr6:146343214 G/A cg23711669 chr6:146136114 FBXO30 0.86 9.23 0.64 9.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs3796352 0.764 rs11714902 chr3:53101544 G/C cg27565382 chr3:53032988 SFMBT1 0.44 4.63 0.38 8.99e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6543140 0.929 rs11465700 chr2:103057668 G/A cg09003973 chr2:102972529 NA 0.54 4.61 0.38 9.8200000000000008e-06 Blood protein levels; TGCT cis rs7772486 0.875 rs1331639 chr6:146431869 A/G cg05347473 chr6:146136440 FBXO30 -0.54 -5.01 -0.41 1.86e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2549003 1.000 rs2070727 chr5:131820275 C/A cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.92e-6 Asthma (sex interaction); TGCT cis rs6683273 0.775 rs12567387 chr1:3226949 T/C cg17435683 chr1:3230609 PRDM16 -0.4 -4.53 -0.38 1.35e-5 QRS duration; TGCT cis rs11997175 0.574 rs4446694 chr8:33654978 A/G ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs11599315 1.000 rs11599315 chr10:1343017 C/T cg27336068 chr10:1336103 ADARB2 -0.36 -5.29 -0.43 5.43e-7 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs611744 0.934 rs1452021 chr8:109207886 A/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7308134 0.766 rs7966806 chr12:1988167 T/C cg09189752 chr12:2113749 DCP1B -0.58 -4.54 -0.38 1.29e-5 QRS duration in Tripanosoma cruzi seropositivity; TGCT cis rs4325129 1.000 rs6677055 chr1:159462452 G/T cg07417683 chr1:159440267 NA -0.45 -4.63 -0.38 9.16e-6 Obesity-related traits; TGCT cis rs11677370 0.928 rs4849989 chr2:3814727 A/G cg17052675 chr2:3827356 NA -0.27 -4.71 -0.39 6.51e-6 Type 2 diabetes; TGCT cis rs2836950 0.527 rs2836958 chr21:40623526 T/C cg06238570 chr21:40685208 BRWD1 -0.61 -6.34 -0.49 3.97e-9 Menarche (age at onset); TGCT cis rs7267979 0.932 rs2387891 chr20:25470328 C/G cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7582180 0.764 rs4851293 chr2:100925106 A/T cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs10883723 0.810 rs13287 chr10:104240438 A/G cg05855489 chr10:104503620 C10orf26 -0.58 -5.05 -0.41 1.56e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1371867 0.875 rs1619759 chr8:101337560 T/C cg00191853 chr8:101177733 SPAG1 -0.23 -4.54 -0.38 1.3e-5 Atrioventricular conduction; TGCT cis rs77741769 0.529 rs3213572 chr12:121205078 A/G cg02419362 chr12:121203948 SPPL3 -0.19 -4.49 -0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs2224391 0.628 rs2753224 chr6:5244864 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.98 -6.21 -0.49 7.43e-9 Height; TGCT cis rs28386778 0.805 rs9911714 chr17:61828952 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs10466239 0.730 rs2946992 chr10:43854279 T/C cg08951903 chr10:44070173 ZNF239 0.83 4.85 0.4 3.7e-6 Telomere length; TGCT cis rs8037137 0.915 rs60290423 chr15:91529452 T/C cg23684204 chr15:91497937 RCCD1 0.4 4.68 0.39 7.32e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs10256972 0.521 rs7811577 chr7:1102829 C/G cg03188948 chr7:1209495 NA 0.48 5.97 0.47 2.3e-8 Longevity;Endometriosis; TGCT cis rs2075371 0.931 rs1646697 chr7:133999930 G/A cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs6988636 0.818 rs73339658 chr8:124173007 A/G cg27053337 chr8:124217698 FAM83A 0.67 5.02 0.41 1.79e-6 Urinary uromodulin levels; TGCT cis rs5769765 0.671 rs138833 chr22:50178917 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.32 4.59 0.38 1.09e-5 Schizophrenia; TGCT cis rs931127 0.719 rs2127507 chr11:65454430 A/G cg27068330 chr11:65405492 SIPA1 -0.63 -6.32 -0.49 4.26e-9 Systemic lupus erythematosus; TGCT cis rs11673344 0.542 rs2562598 chr19:37516220 T/C cg08039142 chr19:36980659 ZNF566 0.51 4.8 0.4 4.53e-6 Obesity-related traits; TGCT cis rs7017914 0.967 rs3954897 chr8:71635955 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs10779751 0.770 rs2015818 chr1:11170743 G/A cg08854313 chr1:11322531 MTOR 0.81 7.89 0.58 1.37e-12 Body mass index; TGCT cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs4237845 0.761 rs11172378 chr12:58298161 C/T cg02175503 chr12:58329896 NA 0.49 4.69 0.39 7.02e-6 Intelligence (multi-trait analysis); TGCT cis rs10992471 0.603 rs7045572 chr9:95137964 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -5.59 -0.45 1.36e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs3125734 0.633 rs4979773 chr10:63967731 G/C cg05499367 chr10:63213510 TMEM26 -0.35 -4.85 -0.4 3.7e-6 Rheumatoid arthritis; TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg04025307 chr7:1156635 C7orf50 0.21 5.15 0.42 9.79e-7 Longevity;Endometriosis; TGCT cis rs7044106 0.762 rs10491783 chr9:123450155 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.6 6.34 0.49 3.94e-9 Hip circumference adjusted for BMI; TGCT cis rs9910055 0.659 rs112114764 chr17:42201041 G/T cg19774624 chr17:42201019 HDAC5 0.89 11.12 0.71 2.32e-20 Total body bone mineral density; TGCT cis rs644799 0.526 rs534973 chr11:95633624 A/T cg03916912 chr11:95522834 CEP57;FAM76B 0.51 4.93 0.41 2.53e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs12638540 0.543 rs12487678 chr3:32603358 A/C cg11605617 chr3:32612461 DYNC1LI1 0.77 5.08 0.42 1.34e-6 Mortality in heart failure; TGCT cis rs13191362 0.507 rs1954806 chr6:163051858 G/C cg06582575 chr6:163149167 PACRG;PARK2 -0.59 -5.62 -0.45 1.18e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs174601 0.833 rs174541 chr11:61565908 T/C cg19610905 chr11:61596333 FADS2 -1.1 -11.4 -0.72 4.93e-21 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.07 0.82 4.17e-32 Prudent dietary pattern; TGCT cis rs6901250 0.851 rs607372 chr6:117155929 A/G cg12892004 chr6:117198278 RFX6 -0.54 -6.65 -0.51 8.24e-10 C-reactive protein levels; TGCT cis rs611744 0.934 rs609102 chr8:109227406 A/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs1215050 0.740 rs6854802 chr4:99065480 A/C cg17366294 chr4:99064904 C4orf37 0.58 6.15 0.48 9.93e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs736408 0.522 rs11716747 chr3:52748857 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs10779751 1.000 rs1135172 chr1:11301714 C/T cg08854313 chr1:11322531 MTOR -0.97 -10.22 -0.68 3.79e-18 Body mass index; TGCT cis rs57590327 0.503 rs12638997 chr3:81844912 A/G cg07356753 chr3:81810745 GBE1 -0.67 -6.15 -0.48 9.91e-9 Extraversion; TGCT cis rs78545713 1.000 rs78545713 chr6:26248840 A/G cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.7 -4.44 -0.37 1.93e-5 Iron status biomarkers (total iron binding capacity); TGCT cis rs10504229 0.775 rs17805146 chr8:58161484 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs228437 0.507 rs382498 chr6:134907441 T/C cg09872934 chr6:134495829 SGK1 0.51 4.61 0.38 1e-5 Melanoma; TGCT cis rs727505 0.521 rs66787780 chr7:124791849 G/A cg23710748 chr7:124431027 NA -0.26 -4.51 -0.38 1.47e-5 Lewy body disease; TGCT cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg03264133 chr6:25882463 NA 0.47 4.9 0.4 2.91e-6 Blood metabolite levels; TGCT cis rs9467773 0.620 rs2451738 chr6:26618459 A/T cg11502198 chr6:26597334 ABT1 -0.52 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.903 rs765867 chr10:869901 G/T cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs10883723 0.810 rs3781289 chr10:104244991 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs12210905 0.688 rs79018549 chr6:27513460 G/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs9467711 1.000 rs6939799 chr6:26328366 G/A cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg20007245 chr22:24372913 LOC391322 -0.77 -8.15 -0.59 3.28e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg23131131 chr22:24373011 LOC391322 -0.8 -8.69 -0.62 1.78e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3540 0.533 rs7495080 chr15:91056681 G/A cg22089800 chr15:90895588 ZNF774 -0.74 -7.56 -0.56 7.83e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT trans rs7618501 0.521 rs11712056 chr3:49914397 T/C cg21659725 chr3:3221576 CRBN 0.72 8.19 0.59 2.73e-13 Intelligence (multi-trait analysis); TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg24675658 chr1:53192096 ZYG11B -0.84 -10.27 -0.68 2.8e-18 Monocyte count; TGCT cis rs933688 1.000 rs11959525 chr5:90703840 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 8.52 0.61 4.61e-14 Smoking behavior; TGCT cis rs7432375 0.610 rs7633629 chr3:136517028 T/A cg15507776 chr3:136538369 TMEM22 0.55 5.64 0.45 1.1e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs6921919 0.583 rs9468367 chr6:28360246 C/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.32 -0.43 4.76e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7178572 0.962 rs1022172 chr15:77793359 A/G cg22256960 chr15:77711686 NA -0.92 -10.57 -0.69 5.1e-19 Type 2 diabetes; TGCT cis rs9486715 0.838 rs7770889 chr6:96858453 C/T cg06623918 chr6:96969491 KIAA0776 -1.09 -14.0 -0.78 2.69e-27 Headache; TGCT cis rs8084125 0.832 rs62105178 chr18:74950635 C/T cg05528293 chr18:74961138 GALR1 0.52 5.18 0.42 8.65e-7 Obesity-related traits; TGCT cis rs10791097 0.694 rs7125622 chr11:130743388 T/C cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4665809 0.590 rs6730310 chr2:26419470 C/G cg26119090 chr2:26468346 HADHA;HADHB -0.93 -6.89 -0.53 2.52e-10 Gut microbiome composition (summer); TGCT cis rs6570726 0.935 rs407721 chr6:145871354 A/C cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs1153858 1.000 rs2453541 chr15:45645378 G/A cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs17401966 0.838 rs6541089 chr1:10402785 A/G cg19773385 chr1:10388646 KIF1B -0.23 -5.38 -0.44 3.57e-7 Hepatocellular carcinoma; TGCT cis rs10479542 0.766 rs6894980 chr5:178974592 C/T cg19626725 chr5:178986131 RUFY1 0.46 5.96 0.47 2.38e-8 Lung cancer; TGCT cis rs210138 1.000 rs210138 chr6:33542538 C/T cg24505687 chr6:33548425 BAK1 -0.53 -6.13 -0.48 1.06e-8 Testicular germ cell tumor; TGCT cis rs7226408 0.857 rs7233017 chr18:34529710 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2072499 0.966 rs2853641 chr1:156181770 A/G cg24450063 chr1:156163899 SLC25A44 1.17 17.12 0.84 1.84e-34 Testicular germ cell tumor; TGCT cis rs7772486 0.790 rs7753833 chr6:146161432 C/A cg23711669 chr6:146136114 FBXO30 0.91 10.4 0.68 1.38e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs1499614 1.000 rs1882655 chr7:66147057 T/C cg18252515 chr7:66147081 NA 1.26 7.95 0.58 9.71e-13 Gout; TGCT cis rs6866344 0.697 rs62392831 chr5:178134365 A/G cg10224037 chr5:178157518 ZNF354A 0.95 8.47 0.61 6.06e-14 Neutrophil percentage of white cells; TGCT cis rs208520 0.690 rs1580430 chr6:66715162 T/A cg07460842 chr6:66804631 NA 0.96 10.21 0.68 3.9e-18 Exhaled nitric oxide output; TGCT cis rs617219 0.671 rs2607144 chr5:78556798 G/T cg05890484 chr5:78407552 BHMT 0.4 5.27 0.43 5.84e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs7666738 0.830 rs11935588 chr4:98979862 A/G cg18180107 chr4:99064573 C4orf37 -0.57 -5.11 -0.42 1.19e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs9640161 0.789 rs2159234 chr7:150020422 A/T cg10018233 chr7:150070692 REPIN1 0.32 4.63 0.38 8.98e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs2228479 0.867 rs75110337 chr16:89962635 C/A cg06558623 chr16:89946397 TCF25 0.57 6.89 0.53 2.56e-10 Skin colour saturation; TGCT cis rs2072499 0.833 rs2251636 chr1:156202809 G/C cg06970220 chr1:156163860 SLC25A44 0.66 6.01 0.47 1.92e-8 Testicular germ cell tumor; TGCT cis rs7208859 0.623 rs216423 chr17:28942109 G/C cg04154034 chr17:28927549 LRRC37B2 0.74 4.56 0.38 1.22e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs36093844 0.898 rs80079882 chr11:85590955 T/C cg25872744 chr11:85566296 CCDC83 -0.52 -4.73 -0.39 6.09e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs904251 0.504 rs1757188 chr6:37483808 A/G cg25019722 chr6:37503610 NA -0.51 -7.96 -0.58 9.09e-13 Cognitive performance; TGCT cis rs2074585 0.646 rs2589964 chr15:90922757 A/G cg22089800 chr15:90895588 ZNF774 0.82 9.04 0.63 2.61e-15 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs12367572 1.000 rs7304472 chr12:45262324 A/G cg04608330 chr12:45269318 NELL2 -0.64 -6.56 -0.51 1.33e-9 Gut microbiome composition (summer); TGCT cis rs9467773 0.511 rs11755443 chr6:26891603 T/C cg26531700 chr6:26746687 NA 0.85 8.37 0.6 1.01e-13 Intelligence (multi-trait analysis); TGCT cis rs6724607 1.000 rs7598979 chr2:191453375 A/G cg10560079 chr2:191398806 TMEM194B 0.37 5.33 0.43 4.5e-7 Pulse pressure; TGCT cis rs2594989 0.943 rs62245870 chr3:11439838 G/A cg00170343 chr3:11313890 ATG7 0.66 4.99 0.41 1.96e-6 Circulating chemerin levels; TGCT cis rs9611565 0.546 rs5758426 chr22:42098763 T/G cg13695892 chr22:41940480 POLR3H 0.85 8.19 0.59 2.72e-13 Vitiligo; TGCT cis rs2243480 1.000 rs1638734 chr7:66097539 A/C cg18252515 chr7:66147081 NA -1.23 -7.53 -0.56 9.12e-12 Diabetic kidney disease; TGCT cis rs1729951 0.575 rs1682356 chr3:136692037 T/C cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs13256369 0.789 rs13282500 chr8:8568489 A/T cg18904891 chr8:8559673 CLDN23 0.6 5.51 0.44 1.99e-7 Obesity-related traits; TGCT cis rs13256369 0.802 rs11249884 chr8:8561552 C/T cg17143192 chr8:8559678 CLDN23 -0.54 -5.14 -0.42 1.04e-6 Obesity-related traits; TGCT cis rs7267979 1.000 rs13038834 chr20:25441433 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6840360 0.667 rs9994482 chr4:152391230 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs7119 0.651 rs12917431 chr15:77850184 C/G cg27398640 chr15:77910606 LINGO1 -0.27 -5.15 -0.42 1.01e-6 Type 2 diabetes; TGCT cis rs6684514 1.000 rs6679145 chr1:156256000 T/C cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2019216 0.500 rs2169916 chr17:21884670 G/C cg22648282 chr17:21454238 C17orf51 -0.55 -5.09 -0.42 1.3e-6 Pelvic organ prolapse; TGCT cis rs854765 0.927 rs12943914 chr17:17980671 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.64 6.23 0.49 6.59e-9 Total body bone mineral density; TGCT trans rs12191082 0.878 rs2021916 chr6:46914521 G/T cg15621338 chr7:128577916 IRF5 -1.05 -7.13 -0.54 7.15e-11 Mean platelet volume; TGCT cis rs929354 0.713 rs3802129 chr7:156965297 G/A cg05182265 chr7:156933206 UBE3C -0.39 -8.79 -0.62 1.03e-14 Body mass index; TGCT cis rs7208859 0.673 rs61348930 chr17:29221763 C/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg15242686 chr22:24348715 GSTTP1 0.42 5.41 0.44 3.07e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2013441 0.932 rs3850785 chr17:20185248 A/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7617773 0.780 rs13085251 chr3:48340045 C/T cg11946769 chr3:48343235 NME6 0.82 7.06 0.54 1.03e-10 Coronary artery disease; TGCT cis rs6598955 0.724 rs6656716 chr1:26563105 G/A cg04990556 chr1:26633338 UBXN11 -0.91 -12.03 -0.73 1.46e-22 Obesity-related traits; TGCT cis rs28785552 0.897 rs7259466 chr19:53239369 G/A cg10871876 chr19:53194124 ZNF83 0.6 8.78 0.62 1.07e-14 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs11578119 0.898 rs10919405 chr1:170417755 A/G cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.66e-8 Male-pattern baldness; TGCT cis rs10504229 0.593 rs76922080 chr8:57985837 C/G cg20607798 chr8:58055168 NA 0.58 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs7095607 0.813 rs10997963 chr10:69921903 A/G cg18986048 chr10:69913749 MYPN -0.47 -5.49 -0.44 2.2e-7 Lung function (FVC); TGCT cis rs7524258 0.868 rs1304711 chr1:7270320 G/T cg07173049 chr1:7289937 CAMTA1 -0.29 -4.89 -0.4 3.1e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs78707713 0.560 rs61848436 chr10:71247714 C/T cg12610070 chr10:71211762 TSPAN15 -0.63 -7.48 -0.56 1.2e-11 Venous thromboembolism; TGCT cis rs587847 0.540 rs601024 chr15:37683048 A/G cg16890051 chr15:37175029 LOC145845 -0.37 -4.44 -0.37 1.95e-5 Intraocular pressure; TGCT cis rs17376456 0.597 rs6869110 chr5:93355531 G/A cg25358565 chr5:93447407 FAM172A -0.63 -6.03 -0.48 1.79e-8 Diabetic retinopathy; TGCT cis rs6582630 0.519 rs7294300 chr12:38277359 C/A cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9911578 0.967 rs57869245 chr17:57106630 A/G cg05425664 chr17:57184151 TRIM37 0.64 6.49 0.5 1.84e-9 Intelligence (multi-trait analysis); TGCT cis rs57545798 0.500 rs36094016 chr15:100643420 T/C cg04622200 chr15:100654734 ADAMTS17 0.33 5.59 0.45 1.38e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2230307 0.656 rs644835 chr1:100543962 A/G cg24955406 chr1:100503596 HIAT1 0.81 4.87 0.4 3.32e-6 Carotid intima media thickness; TGCT cis rs7954584 0.616 rs10743185 chr12:122356435 G/A cg22168489 chr12:122356033 WDR66 0.23 5.55 0.45 1.63e-7 Mean corpuscular volume; TGCT cis rs11239930 0.538 rs618575 chr1:146552308 A/C cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs9534288 0.797 rs9534276 chr13:46574317 T/G cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs4434138 0.533 rs11130324 chr3:52770310 T/G cg07507251 chr3:52567010 NT5DC2 0.49 7.17 0.54 6.03e-11 Intelligence (multi-trait analysis); TGCT cis rs422249 0.613 rs174465 chr11:61658800 C/T cg19610905 chr11:61596333 FADS2 0.63 5.53 0.44 1.83e-7 Trans fatty acid levels; TGCT cis rs17331151 0.573 rs2240916 chr3:52859212 T/A cg11137980 chr3:52469226 SEMA3G 0.27 4.83 0.4 3.98e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7100689 0.556 rs10788541 chr10:82016530 T/G cg01528321 chr10:82214614 TSPAN14 0.71 6.72 0.52 6.03e-10 Post bronchodilator FEV1; TGCT cis rs10488031 0.557 rs34616132 chr7:37085259 A/T cg06458904 chr7:36312573 EEPD1 0.56 4.7 0.39 6.79e-6 QT interval; TGCT cis rs208520 0.731 rs12206488 chr6:66999917 G/T cg07460842 chr6:66804631 NA 0.78 6.57 0.51 1.25e-9 Exhaled nitric oxide output; TGCT cis rs5769707 0.967 rs739241 chr22:50052921 G/A cg10356904 chr22:49881777 NA -0.23 -4.6 -0.38 1.02e-5 Monocyte count;Monocyte percentage of white cells; TGCT trans rs941408 1.000 rs1736180 chr19:2796021 C/T cg22153745 chr1:153894579 GATAD2B -0.62 -6.82 -0.52 3.54e-10 Total cholesterol levels; TGCT cis rs6570726 0.791 rs425999 chr6:145819370 C/A cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9311474 0.508 rs12629701 chr3:52619836 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.23e-17 Electroencephalogram traits; TGCT cis rs7072216 0.763 rs3814142 chr10:100171104 C/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs1552244 0.572 rs3894322 chr3:10168965 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs9325144 0.534 rs1843866 chr12:38703160 G/T cg26384229 chr12:38710491 ALG10B 0.68 6.27 0.49 5.35e-9 Morning vs. evening chronotype; TGCT cis rs7267979 0.932 rs424487 chr20:25468131 C/G cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4443100 0.670 rs13054331 chr22:23407063 G/A cg14186256 chr22:23484241 RTDR1 0.57 4.47 0.37 1.76e-5 Serum parathyroid hormone levels; TGCT cis rs7666738 0.830 rs6855393 chr4:99056534 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1005277 0.579 rs2505197 chr10:38393310 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs68170813 0.652 rs17482494 chr7:107168487 T/C cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs80033912 0.713 rs7629936 chr3:49836707 G/A cg03060546 chr3:49711283 APEH 0.67 6.21 0.49 7.21e-9 Intelligence (multi-trait analysis); TGCT cis rs11122272 0.735 rs2790880 chr1:231534259 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.32 -0.49 4.29e-9 Hemoglobin concentration; TGCT cis rs2762353 0.776 rs1165190 chr6:25848019 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.43 -4.56 -0.38 1.22e-5 Blood metabolite levels; TGCT cis rs9467773 0.967 rs1535276 chr6:26520941 T/C cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs9581857 0.585 rs9581875 chr13:28099678 A/G cg22138327 chr13:27999177 GTF3A 0.72 4.75 0.39 5.45e-6 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs7666738 0.716 rs35195511 chr4:98859660 G/A cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12048904 0.619 rs3737581 chr1:101341083 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.67 5.23 0.43 7.03e-7 Multiple sclerosis; TGCT trans rs1496653 0.602 rs35152860 chr3:23595594 G/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs7647973 1.000 rs11719762 chr3:49409002 G/C cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT cis rs7647973 0.554 rs13096480 chr3:49658084 A/G cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs72717009 0.825 rs9427397 chr1:161476204 C/T cg23840854 chr1:161414152 NA -0.98 -5.87 -0.47 3.79e-8 Rheumatoid arthritis; TGCT cis rs2832191 0.740 rs2853830 chr21:30416824 A/G cg08807101 chr21:30365312 RNF160 0.65 6.11 0.48 1.19e-8 Dental caries; TGCT cis rs6426558 0.537 rs56219094 chr1:227340191 T/C cg10327440 chr1:227177885 CDC42BPA -0.58 -6.95 -0.53 1.88e-10 Neutrophil percentage of white cells; TGCT cis rs7829975 0.542 rs7844374 chr8:8798684 A/G cg15556689 chr8:8085844 FLJ10661 -0.71 -6.16 -0.48 9.13e-9 Mood instability; TGCT cis rs7267979 0.932 rs417130 chr20:25458320 T/C cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12541335 0.639 rs13257108 chr8:22165043 T/C cg02463440 chr8:22132932 PIWIL2 0.26 5.14 0.42 1.05e-6 Hypertriglyceridemia; TGCT cis rs9467773 0.584 rs1021372 chr6:26632444 T/C cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT cis rs12286929 0.767 rs2507906 chr11:115009670 A/C cg04017736 chr11:115827165 NA 0.19 4.44 0.37 1.99e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1215050 0.791 rs983187 chr4:98816350 A/T cg17366294 chr4:99064904 C4orf37 0.56 6.05 0.48 1.57e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9911578 0.967 rs11079354 chr17:56594460 G/A cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs7833790 0.777 rs1005850 chr8:82692255 G/A cg17211192 chr8:82754475 SNX16 -1.04 -8.46 -0.6 6.42e-14 Diastolic blood pressure; TGCT cis rs12368653 0.666 rs701007 chr12:58113416 C/A cg12615879 chr12:58013172 SLC26A10 0.48 5.8 0.46 5.2e-8 Multiple sclerosis; TGCT trans rs77457752 0.690 rs12349396 chr9:13912144 T/C cg23609682 chr1:3070786 PRDM16 0.51 7.14 0.54 6.89e-11 Breast cancer; TGCT cis rs17331151 0.573 rs13080929 chr3:52885112 A/C cg27565382 chr3:53032988 SFMBT1 0.46 5.66 0.45 9.93e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6490294 0.659 rs737280 chr12:112194976 T/C cg10833066 chr12:111807467 FAM109A 0.32 4.96 0.41 2.25e-6 Mean platelet volume; TGCT cis rs6460942 0.915 rs6965564 chr7:12306013 C/T cg06484146 chr7:12443880 VWDE -0.43 -4.6 -0.38 1.04e-5 Coronary artery disease; TGCT cis rs9611565 0.579 rs73178621 chr22:41921665 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs769267 0.965 rs2315024 chr19:19423817 T/A cg02546618 chr19:19431379 KIAA0892;SF4 0.59 4.87 0.4 3.29e-6 Tonsillectomy; TGCT cis rs12291225 0.535 rs11023203 chr11:14409815 G/A cg19336497 chr11:14380999 RRAS2 -0.32 -4.91 -0.4 2.82e-6 Sense of smell; TGCT trans rs208520 1.000 rs12195505 chr6:66986279 T/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs7809950 1.000 rs2520264 chr7:107179344 T/C cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.72e-7 Coronary artery disease; TGCT cis rs7103648 1.000 rs10838709 chr11:47447346 C/T cg20307385 chr11:47447363 PSMC3 1.04 12.68 0.75 3.91e-24 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs9322193 0.847 rs4870054 chr6:150169538 C/T cg13206674 chr6:150067644 NUP43 0.56 4.68 0.39 7.37e-6 Lung cancer; TGCT cis rs7095607 0.813 rs4746732 chr10:69931881 C/T cg18986048 chr10:69913749 MYPN 0.46 5.24 0.43 6.63e-7 Lung function (FVC); TGCT cis rs317689 0.702 rs544696 chr12:69749939 T/C cg14784868 chr12:69753453 YEATS4 0.67 5.99 0.47 2.1e-8 Response to diuretic therapy; TGCT trans rs208520 0.739 rs1935894 chr6:66891434 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -10.21 -0.68 4.02e-18 Exhaled nitric oxide output; TGCT cis rs11711311 0.911 rs13321446 chr3:113522544 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -6.89 -0.53 2.46e-10 IgG glycosylation; TGCT cis rs7811142 0.830 rs3087502 chr7:99955364 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs4891159 0.548 rs617823 chr18:74120233 A/G cg24786174 chr18:74118243 ZNF516 0.69 14.59 0.8 1.08e-28 Longevity; TGCT cis rs17102423 0.530 rs4902357 chr14:65542067 C/G cg11161011 chr14:65562177 MAX -0.47 -6.48 -0.5 1.95e-9 Obesity-related traits; TGCT cis rs10782582 0.609 rs1498311 chr1:76254726 A/C cg05598546 chr1:76251766 SNORD45C;RABGGTB -0.54 -4.79 -0.4 4.69e-6 Daytime sleep phenotypes; TGCT cis rs1865760 0.865 rs9467648 chr6:25957933 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs151997 1.000 rs152803 chr5:50212120 C/T cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs2354432 0.607 rs7553584 chr1:146693429 A/G cg25205988 chr1:146714368 CHD1L -1.33 -6.35 -0.5 3.68e-9 Mitochondrial DNA levels; TGCT cis rs10206020 0.836 rs10202105 chr2:1553301 C/T cg12573674 chr2:1569213 NA -0.48 -4.83 -0.4 3.96e-6 IgG glycosylation; TGCT cis rs9291683 0.609 rs7678012 chr4:9993772 T/C cg11266682 chr4:10021025 SLC2A9 0.67 9.24 0.64 8.89e-16 Bone mineral density; TGCT cis rs2836974 0.568 rs429955 chr21:40539760 G/A cg06238570 chr21:40685208 BRWD1 0.8 9.09 0.63 1.95e-15 Cognitive function; TGCT cis rs763014 0.966 rs4984904 chr16:680809 C/G cg09263875 chr16:632152 PIGQ 0.31 6.89 0.53 2.52e-10 Height; TGCT cis rs1878931 0.501 rs28735976 chr16:3418419 G/A cg05754148 chr16:3507555 NAT15 -0.33 -4.46 -0.37 1.82e-5 Body mass index (adult); TGCT cis rs524281 0.861 rs2177054 chr11:65944612 C/A cg00563793 chr11:65837595 PACS1 0.56 4.72 0.39 6.28e-6 Electroencephalogram traits; TGCT cis rs36093844 0.904 rs7113656 chr11:85594739 T/C cg25872744 chr11:85566296 CCDC83 -0.41 -4.54 -0.38 1.31e-5 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs61931739 0.500 rs11519123 chr12:34436478 A/G cg06521331 chr12:34319734 NA -0.29 -4.59 -0.38 1.07e-5 Morning vs. evening chronotype; TGCT cis rs2243480 1.000 rs778704 chr7:65863467 T/C cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs2832191 0.740 rs2832175 chr21:30475606 A/G cg08807101 chr21:30365312 RNF160 -0.66 -6.04 -0.48 1.63e-8 Dental caries; TGCT cis rs6582630 0.519 rs11495373 chr12:38275470 T/C cg26384229 chr12:38710491 ALG10B 0.86 7.44 0.56 1.46e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.822 rs28512427 chr4:98919029 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.02 0.41 1.78e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.841 rs115907265 chr4:119730593 G/A cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs7208859 0.623 rs7214570 chr17:29147164 A/G cg13385521 chr17:29058706 SUZ12P 0.75 4.85 0.4 3.56e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11874712 1.000 rs1800636 chr18:43670420 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs1862618 0.756 rs9292125 chr5:56107200 C/T cg24531977 chr5:56204891 C5orf35 -0.76 -7.66 -0.57 4.53e-12 Initial pursuit acceleration; TGCT cis rs7258465 1.000 rs4595905 chr19:18547305 T/A cg06462663 chr19:18546047 ISYNA1 0.2 4.54 0.38 1.33e-5 Breast cancer; TGCT trans rs17685 0.736 rs4732594 chr7:75753273 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs2549003 1.000 rs7734334 chr5:131815004 C/A cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs3847687 0.901 rs12370258 chr12:131527301 G/T cg25772418 chr12:131519998 GPR133 -0.26 -4.46 -0.37 1.83e-5 Longevity; TGCT cis rs2463822 1.000 rs115395195 chr11:62100353 G/A cg06239285 chr11:62104954 ASRGL1 -0.95 -6.56 -0.51 1.33e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs137699 1.000 rs137703 chr22:39750241 A/G cg11247378 chr22:39784982 NA -0.44 -4.71 -0.39 6.48e-6 IgG glycosylation; TGCT cis rs782590 0.608 rs10207590 chr2:55921782 G/C cg03859395 chr2:55845619 SMEK2 -0.74 -7.9 -0.58 1.26e-12 Metabolic syndrome; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg04234412 chr22:24373322 LOC391322 -0.92 -10.92 -0.7 7.14e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3935685 0.874 rs11072662 chr15:77999436 A/G cg03457338 chr15:78040120 NA -0.22 -5.55 -0.45 1.64e-7 Intelligence (multi-trait analysis); TGCT cis rs1218582 0.772 rs11264282 chr1:154867370 G/A cg09359103 chr1:154839909 KCNN3 -0.67 -12.46 -0.75 1.35e-23 Prostate cancer; TGCT cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg17554472 chr22:41940697 POLR3H 0.46 4.72 0.39 6.36e-6 Vitiligo; TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg04389838 chr3:44770851 ZNF501 -0.37 -4.83 -0.4 3.94e-6 Depressive symptoms; TGCT cis rs741677 0.702 rs9893847 chr17:489043 C/G cg15660573 chr17:549704 VPS53 -0.32 -4.47 -0.37 1.76e-5 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction); TGCT cis rs1799949 1.000 rs8176234 chr17:41219780 T/C cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 2.93e-27 Menopause (age at onset); TGCT cis rs1577917 0.666 rs6454471 chr6:86214456 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.59 5.15 0.42 1.01e-6 Response to antipsychotic treatment; TGCT cis rs838147 0.507 rs1704773 chr19:49209566 A/G cg00822241 chr19:49201468 FUT2 0.28 4.54 0.38 1.32e-5 Dietary macronutrient intake; TGCT cis rs7659604 0.537 rs6815973 chr4:122663430 A/T cg06713675 chr4:122721982 EXOSC9 0.59 7.09 0.54 9.18e-11 Type 2 diabetes; TGCT cis rs72781680 0.851 rs12612830 chr2:24134599 C/T cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs4788570 0.615 rs11075894 chr16:71690030 C/T cg06353428 chr16:71660113 MARVELD3 1.55 12.51 0.75 9.87e-24 Intelligence (multi-trait analysis); TGCT cis rs644799 0.672 rs11021347 chr11:95653494 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.7 6.67 0.51 7.5e-10 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs35306767 0.903 rs10904577 chr10:922077 A/G cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT trans rs2727020 0.729 rs588458 chr11:49214048 C/A cg03929089 chr4:120376271 NA 0.65 6.99 0.53 1.47e-10 Coronary artery disease; TGCT cis rs6969780 0.545 rs983184 chr7:27188379 C/T cg07317062 chr7:27170388 HOXA4 -0.44 -4.62 -0.38 9.57e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs3096299 0.667 rs2965947 chr16:89518670 T/C cg06640241 chr16:89574553 SPG7 0.77 8.52 0.61 4.55e-14 Multiple myeloma (IgH translocation); TGCT cis rs2243480 1.000 rs781157 chr7:65478311 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs7954584 0.567 rs1720037 chr12:122382229 G/T cg22168489 chr12:122356033 WDR66 -0.22 -5.19 -0.42 8.32e-7 Mean corpuscular volume; TGCT cis rs12701220 0.817 rs1058727 chr7:1087095 A/G cg07217954 chr7:1067459 C7orf50 -0.45 -4.5 -0.37 1.53e-5 Bronchopulmonary dysplasia; TGCT cis rs2013441 1.000 rs2703817 chr17:20119677 A/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs2486288 0.656 rs7167146 chr15:45571386 A/G cg26924012 chr15:45694286 SPATA5L1 0.76 7.78 0.57 2.38e-12 Glomerular filtration rate; TGCT cis rs3091242 0.781 rs71652378 chr1:25721457 G/C cg10117171 chr1:25599238 RHD -0.36 -5.77 -0.46 5.98e-8 Erythrocyte sedimentation rate; TGCT cis rs2562456 0.917 rs6511256 chr19:21693315 G/T cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs4722166 0.630 rs6461667 chr7:22796743 A/G cg05265849 chr7:22767390 IL6 0.23 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs4665809 1.000 rs2384323 chr2:26306473 C/T cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs7267979 0.866 rs6138609 chr20:25570985 T/A cg16686733 chr20:25566563 NINL 0.56 5.56 0.45 1.59e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854765 0.647 rs854763 chr17:18010095 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.7 7.22 0.54 4.53e-11 Total body bone mineral density; TGCT cis rs854765 0.551 rs12600546 chr17:17867614 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs11650494 0.908 rs73324308 chr17:47405338 T/G cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs13191362 1.000 rs68045643 chr6:163029709 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.56 4.64 0.38 8.87e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs67311347 0.544 rs6787516 chr3:40355616 C/T cg13683864 chr3:40499215 RPL14 -0.84 -7.85 -0.58 1.71e-12 Renal cell carcinoma; TGCT cis rs826838 0.935 rs1843639 chr12:39178919 C/A cg26384229 chr12:38710491 ALG10B 1.0 8.98 0.63 3.56e-15 Heart rate; TGCT cis rs9486719 0.948 rs2472904 chr6:96874962 T/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs3806843 0.576 rs550475 chr5:140273528 G/C cg09824255 chr5:140014002 CD14 0.27 4.74 0.39 5.73e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs8180040 1.000 rs295458 chr3:47385585 C/A cg27129171 chr3:47204927 SETD2 0.69 8.73 0.62 1.47e-14 Colorectal cancer; TGCT cis rs981844 1.000 rs17299041 chr4:154673127 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs6993813 0.620 rs7016585 chr8:120030098 C/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs6570726 0.935 rs371744 chr6:145841024 C/T cg23711669 chr6:146136114 FBXO30 0.7 6.46 0.5 2.12e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs4938534 0.559 rs1944919 chr11:111259876 A/C cg24049888 chr11:111250129 POU2AF1 0.34 5.8 0.46 5.27e-8 Primary biliary cholangitis; TGCT cis rs5769765 0.646 rs9616205 chr22:50309915 A/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.15 -9.85 -0.66 2.93e-17 Schizophrenia; TGCT cis rs601339 0.877 rs2649991 chr12:123179461 A/G cg11919336 chr12:123188078 GPR109A 0.64 7.86 0.58 1.61e-12 Adiponectin levels; TGCT cis rs727563 0.594 rs132807 chr22:42071584 T/C cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3862435 0.706 rs2589947 chr15:90949177 G/A cg14166756 chr15:90894880 ZNF774 -0.28 -4.61 -0.38 9.95e-6 Response to exercise (triglyceride level interaction); TGCT cis rs4665809 1.000 rs750452 chr2:26324995 G/A cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs858239 0.698 rs858295 chr7:23245569 A/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.21 -0.42 7.52e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9894429 1.000 rs3935543 chr17:79579874 T/C cg21028142 chr17:79581711 NPLOC4 0.29 6.81 0.52 3.83e-10 Eye color traits; TGCT cis rs9372253 1.000 rs2235989 chr6:110714584 A/T cg13266496 chr6:110720918 DDO -0.45 -5.55 -0.45 1.64e-7 Platelet distribution width; TGCT cis rs910187 0.641 rs3186647 chr20:45817067 T/C cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs2013441 1.000 rs2703787 chr17:20158665 A/G cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs2204008 0.604 rs11172718 chr12:38069819 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.56e-12 Bladder cancer; TGCT cis rs9467773 1.000 rs9467796 chr6:26568411 A/G cg09904177 chr6:26538194 HMGN4 0.69 6.84 0.52 3.23e-10 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.902 rs3799344 chr6:25786993 C/T cg03517284 chr6:25882590 NA 0.47 4.76 0.39 5.38e-6 Blood metabolite levels; TGCT cis rs3091242 0.933 rs35148262 chr1:25766623 A/G cg23205692 chr1:25664452 TMEM50A 0.48 5.0 0.41 1.92e-6 Erythrocyte sedimentation rate; TGCT cis rs9790314 0.875 rs55688744 chr3:160944222 G/A cg03342759 chr3:160939853 NMD3 -0.51 -5.73 -0.46 7.05e-8 Morning vs. evening chronotype; TGCT cis rs9383153 1.000 rs9383153 chr6:16343056 A/G cg14009473 chr6:15502099 JARID2 0.59 4.86 0.4 3.43e-6 Gambling; TGCT cis rs7523273 0.565 rs2025374 chr1:207887536 A/G cg22525895 chr1:207977042 MIR29B2 -0.35 -5.83 -0.46 4.47e-8 Schizophrenia; TGCT cis rs9972944 0.756 rs2024273 chr17:63768972 A/G cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs8017423 0.935 rs2236403 chr14:90736325 C/T cg04374321 chr14:90722782 PSMC1 -0.75 -7.31 -0.55 2.88e-11 Mortality in heart failure; TGCT cis rs6921919 0.583 rs6899389 chr6:28381140 C/A cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1167827 1.000 rs1167827 chr7:75163169 A/G cg08200252 chr7:75115859 POM121C 0.35 5.45 0.44 2.66e-7 Body mass index;BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6912958 0.702 rs6906769 chr6:88235949 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs7647973 1.000 rs7619789 chr3:49476263 T/C cg07690219 chr3:49449608 TCTA;RHOA -0.53 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs7223966 0.960 rs113155878 chr17:61706560 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.76 0.39 5.39e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9811920 0.535 rs704572 chr3:99482314 G/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.39 4.69 0.39 7.22e-6 Axial length; TGCT cis rs6977660 0.562 rs2189566 chr7:19768960 G/A cg05791153 chr7:19748676 TWISTNB 1.03 6.95 0.53 1.88e-10 Thyroid stimulating hormone; TGCT cis rs7213347 0.555 rs2760751 chr17:2028106 A/G cg20777128 chr17:1945076 DPH1;OVCA2 -0.56 -4.9 -0.4 2.89e-6 Total body bone mineral density; TGCT cis rs9467603 0.925 rs13199775 chr6:25828782 A/T cg16898833 chr6:26189333 HIST1H4D 1.21 5.94 0.47 2.64e-8 Intelligence (multi-trait analysis); TGCT cis rs9486715 0.867 rs1855533 chr6:97050265 T/C cg18709589 chr6:96969512 KIAA0776 -0.84 -8.23 -0.59 2.19e-13 Headache; TGCT cis rs1580019 0.587 rs6972365 chr7:32548931 T/A cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.96 0.41 2.25e-6 Cognitive ability; TGCT cis rs3771570 0.901 rs56129392 chr2:242242439 C/T cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs11955175 0.850 rs111959286 chr5:40704141 A/T cg17351974 chr5:40835760 RPL37 0.82 5.28 0.43 5.68e-7 Bipolar disorder and schizophrenia; TGCT cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg10108389 chr3:44770937 ZNF501 -0.48 -4.94 -0.41 2.48e-6 Depressive symptoms; TGCT cis rs2933343 1.000 rs2929859 chr3:128608341 T/G cg11901034 chr3:128598214 ACAD9 -0.65 -5.13 -0.42 1.09e-6 IgG glycosylation; TGCT cis rs3806843 0.576 rs246006 chr5:140339228 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs7552404 0.627 rs12127049 chr1:76353248 G/A cg22875332 chr1:76189707 ACADM 0.69 6.91 0.53 2.24e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1799949 0.501 rs35399157 chr17:41411602 G/C cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs2153535 0.541 rs1414353 chr6:8485642 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT trans rs208515 0.525 rs10944869 chr6:66687576 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs4786125 0.804 rs6500850 chr16:6896389 A/T cg03623568 chr16:6915990 A2BP1 -0.33 -4.73 -0.39 5.95e-6 Heart rate variability traits (SDNN); TGCT cis rs78487399 0.808 rs6726643 chr2:43753746 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12681288 0.748 rs7000148 chr8:1016383 G/C cg21347738 chr8:1310380 NA -0.22 -4.59 -0.38 1.08e-5 Schizophrenia; TGCT cis rs11627546 0.615 rs1958084 chr14:70366045 A/G cg10496350 chr14:71275911 MAP3K9 -0.89 -4.5 -0.37 1.52e-5 Red blood cell traits; TGCT cis rs6095298 0.595 rs4809728 chr20:47440220 C/G cg12307787 chr20:48099359 KCNB1 0.44 4.65 0.39 8.52e-6 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.0 -8.0 -0.58 7.56e-13 Platelet count; TGCT cis rs7959452 0.535 rs4761228 chr12:69682327 G/A cg11871910 chr12:69753446 YEATS4 0.62 6.23 0.49 6.65e-9 Blood protein levels; TGCT cis rs10464366 0.957 rs12667577 chr7:39095133 T/G cg18850127 chr7:39170497 POU6F2 0.21 4.49 0.37 1.62e-5 IgG glycosylation; TGCT cis rs67311347 0.544 rs6787516 chr3:40355616 C/T cg17264618 chr3:40429014 ENTPD3 0.3 4.48 0.37 1.69e-5 Renal cell carcinoma; TGCT cis rs4888262 0.545 rs4072450 chr16:74666634 G/C cg01733217 chr16:74700730 RFWD3 0.73 7.26 0.55 3.77e-11 Testicular germ cell tumor; TGCT cis rs7666738 0.830 rs1593572 chr4:98979322 A/G cg05340658 chr4:99064831 C4orf37 -0.45 -5.05 -0.41 1.54e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9527 0.614 rs11191589 chr10:104930382 T/C cg15744005 chr10:104629667 AS3MT -0.4 -4.59 -0.38 1.08e-5 Arsenic metabolism; TGCT cis rs2239547 0.521 rs9682464 chr3:52888485 C/T cg11645453 chr3:52864694 ITIH4 0.35 5.77 0.46 5.97e-8 Schizophrenia; TGCT cis rs453301 0.686 rs10217044 chr8:8894752 A/G cg15556689 chr8:8085844 FLJ10661 -0.61 -5.23 -0.42 7.1e-7 Joint mobility (Beighton score); TGCT cis rs1552244 0.554 rs6800204 chr3:9995404 A/G cg00149659 chr3:10157352 C3orf10 0.66 4.89 0.4 3.04e-6 Alzheimer's disease; TGCT cis rs6964587 0.967 rs10953063 chr7:91576958 A/G cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs904251 0.523 rs914348 chr6:37484729 G/A cg01843034 chr6:37503916 NA -0.53 -7.08 -0.54 9.58e-11 Cognitive performance; TGCT cis rs3733585 0.673 rs4292333 chr4:9953871 G/A cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7927771 0.832 rs10769258 chr11:47391039 C/T cg21462715 chr11:47870315 NUP160 -0.58 -4.74 -0.39 5.68e-6 Subjective well-being; TGCT cis rs3820068 0.581 rs72645888 chr1:15929922 C/A cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs9894429 0.789 rs7213849 chr17:79567610 C/T cg21028142 chr17:79581711 NPLOC4 -0.3 -7.03 -0.53 1.2e-10 Eye color traits; TGCT cis rs13256369 0.865 rs13282523 chr8:8577293 C/G cg18904891 chr8:8559673 CLDN23 0.58 5.29 0.43 5.44e-7 Obesity-related traits; TGCT cis rs2242194 0.816 rs6671688 chr1:154994265 T/C cg06221963 chr1:154839813 KCNN3 -0.49 -6.17 -0.48 9e-9 Schizophrenia; TGCT cis rs8084125 0.765 rs62105165 chr18:74944464 A/G cg05528293 chr18:74961138 GALR1 0.49 4.84 0.4 3.74e-6 Obesity-related traits; TGCT cis rs909674 0.775 rs8138462 chr22:39839670 G/C cg05872129 chr22:39784769 NA -0.98 -9.83 -0.66 3.19e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs13242816 1.000 rs35184471 chr7:116133246 G/A cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs926938 0.520 rs6671984 chr1:115257521 C/T cg12756093 chr1:115239321 AMPD1 -0.41 -5.4 -0.44 3.21e-7 Autism; TGCT cis rs9303401 0.659 rs7210432 chr17:56668170 C/T cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs9393692 0.905 rs1125000 chr6:26287256 C/T cg13736514 chr6:26305472 NA -0.37 -5.33 -0.43 4.48e-7 Educational attainment; TGCT cis rs9733 0.596 rs11586422 chr1:150679358 C/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs2228479 0.717 rs2270460 chr16:89972416 C/A cg06558623 chr16:89946397 TCF25 0.51 6.5 0.5 1.75e-9 Skin colour saturation; TGCT cis rs2120019 0.638 rs34492112 chr15:75294917 G/A cg17294928 chr15:75287854 SCAMP5 0.94 9.07 0.63 2.2e-15 Blood trace element (Zn levels); TGCT cis rs2963155 0.518 rs862489 chr5:142634355 T/C cg17617527 chr5:142782415 NR3C1 0.85 6.29 0.49 4.9e-9 Breast cancer; TGCT trans rs4824093 0.535 rs73441802 chr22:50273916 G/A cg09872104 chr7:134855509 C7orf49 -1.0 -8.27 -0.6 1.77e-13 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7647973 1.000 rs2140270 chr3:49439440 A/G cg06212747 chr3:49208901 KLHDC8B -0.59 -4.72 -0.39 6.19e-6 Menarche (age at onset); TGCT cis rs79349575 0.783 rs62075839 chr17:46996434 G/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs736408 0.527 rs2577831 chr3:52628056 C/A cg07507251 chr3:52567010 NT5DC2 0.51 7.63 0.57 5.29e-12 Bipolar disorder; TGCT cis rs6582630 0.555 rs10880607 chr12:38508184 A/G cg26384229 chr12:38710491 ALG10B 0.89 8.14 0.59 3.55e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs782590 0.774 rs782637 chr2:55894247 T/C cg18811423 chr2:55921094 PNPT1 0.65 6.76 0.52 4.79e-10 Metabolic syndrome; TGCT cis rs2204008 0.837 rs10876019 chr12:37985477 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs7681440 0.904 rs3756063 chr4:90757394 G/C cg26578617 chr4:90757533 SNCA -0.48 -4.96 -0.41 2.31e-6 Dementia with Lewy bodies; TGCT cis rs142483589 1 rs142483589 chr9:139320323 CCG/C cg13741927 chr9:139327495 INPP5E -0.27 -6.26 -0.49 5.64e-9 White blood cell count; TGCT cis rs56104184 0.830 rs28556985 chr19:49351149 C/T cg17863274 chr19:49399704 TULP2 -0.51 -6.28 -0.49 5.21e-9 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs8068544 0.818 rs75771390 chr17:40194054 A/G cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.08 -5.02 -0.41 1.75e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg10108389 chr3:44770937 ZNF501 -0.47 -4.89 -0.4 3.12e-6 Depressive symptoms; TGCT cis rs453301 0.686 rs3989373 chr8:8911308 G/T cg15556689 chr8:8085844 FLJ10661 -0.61 -5.07 -0.41 1.42e-6 Joint mobility (Beighton score); TGCT cis rs7666738 0.830 rs72882693 chr4:98960804 T/A cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs4919044 0.756 rs2486686 chr10:94778511 G/T cg05127821 chr10:94822908 CYP26C1 -0.77 -5.03 -0.41 1.71e-6 Coronary artery disease; TGCT cis rs7226408 0.901 rs17652935 chr18:34756530 T/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1552244 0.510 rs13075308 chr3:10034925 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs7647973 1.000 rs62259933 chr3:49469703 G/A cg05785598 chr3:49045655 WDR6 -0.38 -4.5 -0.37 1.57e-5 Menarche (age at onset); TGCT cis rs4819052 1.000 rs2297286 chr21:46707897 C/G cg06618935 chr21:46677482 NA -0.38 -4.97 -0.41 2.22e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2072499 0.966 rs11587860 chr1:156156951 G/C cg06970220 chr1:156163860 SLC25A44 0.6 5.1 0.42 1.22e-6 Testicular germ cell tumor; TGCT cis rs35306767 0.953 rs1106064 chr10:957211 G/A cg20503657 chr10:835505 NA 0.68 9.49 0.65 2.12e-16 Eosinophil percentage of granulocytes; TGCT cis rs826838 0.806 rs826873 chr12:39121305 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.76 -0.57 2.68e-12 Heart rate; TGCT cis rs12497850 0.931 rs6446205 chr3:49035211 C/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.46 -0.44 2.5e-7 Parkinson's disease; TGCT cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg11494091 chr17:61959527 GH2 0.43 7.3 0.55 3.05e-11 Height; TGCT cis rs6951245 1.000 rs74652290 chr7:1090109 G/A cg18402987 chr7:1209562 NA 0.75 6.35 0.5 3.67e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs765787 0.530 rs4444275 chr15:45535347 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs7675861 1.000 rs7675861 chr4:5849821 T/C cg14241509 chr4:6196512 JAKMIP1 0.25 4.48 0.37 1.69e-5 Dysphagia; TGCT cis rs9660180 0.967 rs6603803 chr1:1812688 A/G cg23982607 chr1:1823379 GNB1 -0.55 -8.49 -0.61 5.45e-14 Body mass index; TGCT cis rs9611519 0.929 rs12484477 chr22:41429084 G/A cg13695892 chr22:41940480 POLR3H -0.53 -4.62 -0.38 9.54e-6 Neuroticism; TGCT cis rs6964587 1.000 rs9690208 chr7:91735613 T/A cg22709100 chr7:91322751 NA 0.28 4.61 0.38 9.79e-6 Breast cancer; TGCT cis rs453301 0.686 rs11787026 chr8:8902371 A/T cg15556689 chr8:8085844 FLJ10661 0.67 5.46 0.44 2.46e-7 Joint mobility (Beighton score); TGCT cis rs1843834 0.539 rs6739735 chr2:225405253 A/G cg22455342 chr2:225449267 CUL3 -1.02 -10.66 -0.69 3.16e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs6570726 0.791 rs10457788 chr6:145921136 T/A cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.851 rs6089827 chr20:61668845 C/T cg08564027 chr20:61660810 NA 0.36 6.47 0.5 2.07e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs79349575 0.783 rs59270107 chr17:47026185 A/T cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs11785400 0.793 rs1056012 chr8:143740167 A/G cg10596483 chr8:143751796 JRK 0.55 5.48 0.44 2.29e-7 Schizophrenia; TGCT cis rs3091242 0.933 rs1534954 chr1:25761924 A/T cg10117171 chr1:25599238 RHD -0.33 -5.43 -0.44 2.81e-7 Erythrocyte sedimentation rate; TGCT cis rs910187 0.624 rs6018311 chr20:45792634 A/G cg27589058 chr20:45804311 EYA2 -0.36 -6.87 -0.53 2.72e-10 Migraine; TGCT cis rs769267 0.965 rs2074296 chr19:19373689 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.59 4.74 0.39 5.85e-6 Tonsillectomy; TGCT cis rs9916302 0.904 rs7208274 chr17:37513796 C/T cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs6088580 0.634 rs1890002 chr20:32919219 A/G cg06115741 chr20:33292138 TP53INP2 -0.54 -4.74 -0.39 5.7e-6 Glomerular filtration rate (creatinine); TGCT cis rs11190604 1.000 rs11190540 chr10:102202629 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs12971120 0.891 rs3794955 chr18:72174827 C/T cg26446133 chr18:72167187 CNDP2 -0.35 -5.89 -0.47 3.42e-8 Refractive error; TGCT cis rs950169 0.656 rs11632395 chr15:85145793 C/A cg11189052 chr15:85197271 WDR73 0.81 6.94 0.53 1.94e-10 Schizophrenia; TGCT cis rs9399135 0.967 rs34546690 chr6:135369709 T/C cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs42648 0.596 rs194524 chr7:89861832 G/A cg25739043 chr7:89950458 NA -0.52 -5.0 -0.41 1.88e-6 Homocysteine levels; TGCT cis rs7771547 0.508 rs1570368 chr6:36437136 C/G cg07856975 chr6:36356162 ETV7 0.21 4.74 0.39 5.86e-6 Platelet distribution width; TGCT cis rs1525293 0.507 rs12698980 chr7:70508532 G/A cg21135135 chr7:70597687 WBSCR17 0.6 5.8 0.46 5.12e-8 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs9658691 0.920 rs72809352 chr10:90742624 A/G cg03111039 chr10:90751583 FAS;ACTA2 -0.79 -5.7 -0.46 8.11e-8 Mosquito bite size; TGCT cis rs7769051 1.000 rs9493438 chr6:133098349 T/C cg22852734 chr6:133119734 C6orf192 1.22 7.01 0.53 1.38e-10 Type 2 diabetes nephropathy; TGCT cis rs11143230 1.000 rs17628494 chr9:74889167 C/T cg02514559 chr9:74675332 C9orf57 -0.22 -4.45 -0.37 1.88e-5 Suicidal ideation; TGCT cis rs11112613 0.653 rs941101 chr12:105937098 T/G cg03607813 chr12:105948248 NA 0.47 5.32 0.43 4.62e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs314370 0.951 rs12667888 chr7:100474289 T/C cg10426581 chr7:100472382 SRRT 1.0 10.93 0.7 6.98e-20 Resting heart rate; TGCT cis rs3858526 0.628 rs4237762 chr11:5956626 A/C cg24799795 chr11:5959658 NA -0.35 -4.66 -0.39 8.16e-6 DNA methylation (variation); TGCT cis rs7914558 0.966 rs10786725 chr10:104682357 T/C cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7666738 0.830 rs6823718 chr4:99063202 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4886920 0.662 rs4322626 chr15:78105835 A/G cg25212270 chr15:78015279 NA -0.29 -4.63 -0.38 8.97e-6 Neuroticism; TGCT cis rs950169 0.614 rs12911536 chr15:84673030 G/T cg11189052 chr15:85197271 WDR73 0.67 5.19 0.42 8.46e-7 Schizophrenia; TGCT cis rs9926296 0.632 rs4785717 chr16:89801133 A/G cg26513180 chr16:89883248 FANCA 0.71 6.86 0.52 2.86e-10 Vitiligo; TGCT cis rs10114408 0.959 rs7048848 chr9:96664058 C/T cg13679303 chr9:96623674 NA -0.36 -4.66 -0.39 8e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs10504229 0.639 rs16921812 chr8:58106737 C/T cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.666 rs35182074 chr21:40685284 A/C cg11644478 chr21:40555479 PSMG1 -0.58 -5.1 -0.42 1.23e-6 Cognitive function; TGCT cis rs68092024 0.704 rs704576 chr3:99487154 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 5.94 0.47 2.64e-8 Cleft lip with or without cleft palate; TGCT cis rs9902453 0.934 rs7223645 chr17:28491029 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs11874712 1.000 rs2298787 chr18:43669980 T/C cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs1976403 0.659 rs10799699 chr1:21820961 C/T cg17800788 chr1:21766015 NBPF3 0.24 4.51 0.38 1.46e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs17376456 0.877 rs10062711 chr5:93348659 G/A cg25358565 chr5:93447407 FAM172A 0.92 8.37 0.6 1.05e-13 Diabetic retinopathy; TGCT cis rs9611565 0.592 rs5751101 chr22:41828111 C/T cg06634786 chr22:41940651 POLR3H 0.84 8.04 0.59 5.97e-13 Vitiligo; TGCT cis rs7412746 0.658 rs72704685 chr1:150897687 C/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs736408 0.509 rs1108842 chr3:52720080 A/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.6 -6.01 -0.48 1.91e-8 Bipolar disorder; TGCT cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg22166914 chr1:53195759 ZYG11B -0.39 -6.46 -0.5 2.18e-9 Monocyte count; TGCT cis rs854765 0.647 rs712268 chr17:18025744 C/G cg04398451 chr17:18023971 MYO15A -0.39 -6.89 -0.53 2.53e-10 Total body bone mineral density; TGCT cis rs1215050 0.791 rs1215055 chr4:98865454 C/T cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2274273 0.564 rs10140164 chr14:55406123 A/G cg01923255 chr14:55878535 KIAA0831 0.52 4.44 0.37 1.99e-5 Protein biomarker; TGCT cis rs17133449 0.718 rs1901635 chr10:4751773 C/T cg04530666 chr10:3759553 NA -0.29 -4.87 -0.4 3.33e-6 Major depressive disorder; TGCT cis rs7267979 0.966 rs4813557 chr20:25292545 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9911578 1.000 rs1057068 chr17:56598439 T/C cg05425664 chr17:57184151 TRIM37 0.62 6.23 0.49 6.62e-9 Intelligence (multi-trait analysis); TGCT cis rs2242073 1.000 rs2242073 chr2:208994045 A/C cg18579327 chr2:208395557 CREB1 0.58 4.48 0.37 1.67e-5 Attention deficit hyperactivity disorder; TGCT cis rs6089829 0.962 rs4586690 chr20:61658595 G/T cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT trans rs7698623 0.717 rs4147245 chr4:88779237 A/C cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs17725255 0.516 rs1205213 chr20:18122278 G/A cg02706653 chr20:17208584 PCSK2 0.56 4.49 0.37 1.59e-5 Anorexia nervosa; TGCT cis rs4665809 1.000 rs2289022 chr2:26350136 G/T cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs57590327 0.679 rs35754586 chr3:81601765 T/C cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs6840360 0.642 rs4696089 chr4:152395733 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs7267979 1.000 rs6115146 chr20:25304507 G/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12136530 0.577 rs4912002 chr1:19793402 G/T cg00755546 chr1:19971792 NBL1 0.38 4.83 0.4 3.87e-6 Lead levels in blood; TGCT cis rs13064411 0.866 rs35278902 chr3:113239021 A/G cg18753928 chr3:113234510 CCDC52 -0.68 -4.74 -0.39 5.8e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs6076065 0.748 rs6048784 chr20:23382652 A/T cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs8177253 0.965 rs8177260 chr3:133480458 T/A cg16414030 chr3:133502952 NA -0.62 -9.73 -0.66 5.69e-17 Iron status biomarkers; TGCT cis rs9911578 0.935 rs304261 chr17:56813782 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs896854 0.654 rs1453377 chr8:95969947 C/T cg09323728 chr8:95962352 TP53INP1 -0.51 -6.45 -0.5 2.23e-9 Type 2 diabetes; TGCT cis rs9296092 0.538 rs9469486 chr6:33516849 G/A cg13560919 chr6:33536144 NA -0.21 -4.74 -0.39 5.87e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7169223 0.653 rs3971703 chr15:79092481 G/C cg03762349 chr15:79060523 ADAMTS7 -0.24 -4.76 -0.39 5.39e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs7246657 0.943 rs10424574 chr19:37838393 A/G cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs4906332 0.899 rs12888042 chr14:103891709 G/A cg26031613 chr14:104095156 KLC1 -0.54 -4.82 -0.4 4.04e-6 Coronary artery disease; TGCT cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs3749237 0.595 rs4855864 chr3:49521974 C/T cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 6.92e-15 Resting heart rate; TGCT cis rs12477438 0.798 rs2309524 chr2:99659510 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs7633770 0.805 rs11130098 chr3:46661926 A/G cg11219411 chr3:46661640 NA -0.36 -5.34 -0.43 4.22e-7 Coronary artery disease; TGCT cis rs7917772 0.582 rs12784963 chr10:104336986 G/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.46 -0.44 2.51e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs916888 0.610 rs199446 chr17:44813169 G/A cg22968622 chr17:43663579 NA -0.99 -9.47 -0.65 2.39e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2862064 1.000 rs6867207 chr5:156450106 G/A cg12943317 chr5:156479607 HAVCR1 -0.45 -5.77 -0.46 6.03e-8 Platelet count; TGCT cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9527 1.000 rs12416687 chr10:104629011 T/C cg15744005 chr10:104629667 AS3MT -0.52 -6.06 -0.48 1.52e-8 Arsenic metabolism; TGCT cis rs11112613 0.775 rs7959699 chr12:105959848 C/A cg03607813 chr12:105948248 NA 0.46 5.58 0.45 1.46e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs11578119 0.933 rs12145961 chr1:170497526 C/G cg09767346 chr1:170501363 GORAB 0.64 5.09 0.42 1.3e-6 Male-pattern baldness; TGCT cis rs11785400 1.000 rs6997670 chr8:143737915 G/A cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs9638182 0.725 rs2074755 chr7:72877166 C/T cg14087351 chr7:73037990 MLXIPL 0.6 4.97 0.41 2.18e-6 Triglycerides; TGCT trans rs629535 0.821 rs650267 chr8:70029160 C/T cg21567404 chr3:27674614 NA 0.58 9.18 0.64 1.22e-15 Dupuytren's disease; TGCT cis rs7819412 0.807 rs6991930 chr8:10963288 G/C cg21775007 chr8:11205619 TDH -0.52 -5.06 -0.41 1.46e-6 Triglycerides; TGCT cis rs10256972 0.539 rs2949174 chr7:1213923 T/C cg07092213 chr7:1199455 ZFAND2A -0.52 -5.68 -0.45 9.09e-8 Longevity;Endometriosis; TGCT trans rs6561151 0.957 rs1373904 chr13:44475398 A/G cg12856521 chr11:46389249 DGKZ 0.69 7.75 0.57 2.8e-12 Crohn's disease; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg10150615 chr22:24372951 LOC391322 -0.96 -11.77 -0.73 6.04e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9674544 0.757 rs3744085 chr17:47131901 A/G cg20966754 chr17:47091339 IGF2BP1 -0.42 -4.46 -0.37 1.81e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs2197308 0.740 rs10880619 chr12:37922720 T/C cg26384229 chr12:38710491 ALG10B 0.89 7.98 0.58 8.43e-13 Morning vs. evening chronotype; TGCT cis rs939658 1.000 rs12439908 chr15:79456381 T/C cg17916960 chr15:79447300 NA 0.54 8.64 0.61 2.42e-14 Refractive error; TGCT trans rs28595532 0.748 rs55949457 chr4:119336174 A/G cg26518628 chr1:97050305 NA -0.56 -6.79 -0.52 4.19e-10 Cannabis dependence symptom count; TGCT cis rs916888 0.779 rs199528 chr17:44843136 C/T cg17911788 chr17:44343683 NA -0.62 -6.7 -0.52 6.65e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9611565 0.559 rs9611619 chr22:41986714 C/T cg17554472 chr22:41940697 POLR3H -0.52 -5.37 -0.43 3.79e-7 Vitiligo; TGCT cis rs7267979 0.668 rs2387977 chr20:25599776 C/T cg16686733 chr20:25566563 NINL -0.47 -4.83 -0.4 3.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12902680 0.739 rs28851955 chr15:46416283 A/C cg13605988 chr15:45421612 DUOX1;DUOXA1 0.33 4.62 0.38 9.28e-6 Neuroticism; TGCT cis rs6089584 0.507 rs28545731 chr20:60634102 C/T cg06108461 chr20:60628389 TAF4 -0.46 -5.72 -0.46 7.61e-8 Body mass index; TGCT cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg23758822 chr17:41437982 NA 0.71 6.75 0.52 5.16e-10 Menopause (age at onset); TGCT cis rs1865760 0.613 rs9379805 chr6:25938764 T/A cg12310025 chr6:25882481 NA -0.53 -5.34 -0.43 4.24e-7 Height; TGCT cis rs1843834 0.898 rs2014887 chr2:225520082 A/G cg22455342 chr2:225449267 CUL3 0.74 7.25 0.55 3.9e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs12410462 0.502 rs78101727 chr1:227732069 C/T cg23173402 chr1:227635558 NA 0.77 4.95 0.41 2.37e-6 Major depressive disorder; TGCT cis rs1371867 0.810 rs1692004 chr8:101247320 T/C cg06636551 chr8:101224915 SPAG1 0.49 6.63 0.51 9.15e-10 Atrioventricular conduction; TGCT cis rs4820539 0.641 rs5759602 chr22:23489362 C/T cg21100191 chr22:23484243 RTDR1 -0.8 -8.95 -0.63 4.31e-15 Bone mineral density; TGCT cis rs9611519 0.531 rs1967708 chr22:41444444 G/C cg03806693 chr22:41940476 POLR3H -0.59 -5.48 -0.44 2.22e-7 Neuroticism; TGCT cis rs4727027 0.933 rs6464940 chr7:148826309 G/T cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs4319547 0.737 rs4758646 chr12:122946507 G/A cg05707623 chr12:122985044 ZCCHC8 -0.66 -5.33 -0.43 4.48e-7 Body mass index; TGCT cis rs7714584 1.000 rs4958426 chr5:150278346 A/C cg22134413 chr5:150180641 NA 1.14 8.32 0.6 1.33e-13 Crohn's disease; TGCT cis rs992157 0.835 rs11677953 chr2:219121663 G/A cg00012203 chr2:219082015 ARPC2 -0.78 -7.64 -0.57 5.16e-12 Colorectal cancer; TGCT cis rs2201728 1.000 rs12510722 chr4:100147101 A/G cg07219303 chr4:100140905 ADH6 -0.35 -5.22 -0.42 7.29e-7 Cardiac Troponin-T levels; TGCT cis rs7666738 0.830 rs6532719 chr4:99043691 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.49 0.56 1.11e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2147959 0.824 rs10916313 chr1:228625882 C/G cg22700015 chr1:228743131 NA -0.57 -4.53 -0.38 1.35e-5 Adult asthma; TGCT cis rs732765 0.909 rs709887 chr14:75369379 T/C cg06637938 chr14:75390232 RPS6KL1 -0.65 -5.51 -0.44 1.99e-7 Non-small cell lung cancer; TGCT cis rs6939532 0.522 rs4712981 chr6:26361430 C/T cg05738196 chr6:26577821 NA -0.53 -5.03 -0.41 1.68e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7324557 0.684 rs9510871 chr13:24384852 C/T cg16602799 chr13:25254742 ATP12A 0.57 4.45 0.37 1.93e-5 Visceral adipose tissue adjusted for BMI; TGCT cis rs7264396 0.790 rs6579255 chr20:34219496 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.67 -0.39 7.62e-6 Total cholesterol levels; TGCT cis rs5750830 0.597 rs4821889 chr22:39777254 T/C cg02038168 chr22:39784481 NA -0.68 -6.13 -0.48 1.05e-8 Intelligence (multi-trait analysis); TGCT cis rs763014 0.966 rs4984675 chr16:670117 T/C cg09263875 chr16:632152 PIGQ 0.31 6.88 0.53 2.65e-10 Height; TGCT cis rs7666738 0.830 rs1111541 chr4:99033860 A/G cg17366294 chr4:99064904 C4orf37 -0.69 -6.87 -0.52 2.79e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs939574 0.512 rs10194278 chr2:220138408 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.78 5.63 0.45 1.14e-7 Platelet distribution width; TGCT cis rs6879260 0.928 rs11739624 chr5:179727290 T/C cg02891314 chr5:179741120 GFPT2 -0.39 -6.43 -0.5 2.46e-9 Height; TGCT cis rs6570726 0.935 rs366621 chr6:145861275 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.51 0.38 1.49e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs60411337 chr4:99046617 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6701037 0.512 rs4650716 chr1:175128711 C/A cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs6076065 0.630 rs2424559 chr20:23430519 A/G cg11657817 chr20:23433608 CST11 0.34 6.15 0.48 9.6e-9 Facial morphology (factor 15, philtrum width); TGCT cis rs709400 0.628 rs4906321 chr14:103878882 C/T cg26031613 chr14:104095156 KLC1 0.71 8.07 0.59 5.23e-13 Body mass index; TGCT cis rs4727027 0.933 rs28767030 chr7:148825918 T/G cg23583168 chr7:148888333 NA -0.72 -9.18 -0.64 1.18e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs10504229 1.000 rs6989060 chr8:58178989 T/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7582180 0.629 rs36103184 chr2:100942634 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs12579753 0.879 rs11615729 chr12:82128318 T/A cg21231944 chr12:82153410 PPFIA2 -0.36 -4.7 -0.39 6.72e-6 Resting heart rate; TGCT cis rs7772486 0.846 rs7755440 chr6:146375906 T/C cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10746514 0.813 rs9724918 chr1:232248087 C/T cg09506761 chr1:232265262 NA 0.46 4.71 0.39 6.41e-6 Response to statin therapy; TGCT cis rs981844 0.696 rs7695605 chr4:154635436 C/G cg14289246 chr4:154710475 SFRP2 0.9 6.89 0.53 2.45e-10 Response to statins (LDL cholesterol change); TGCT cis rs4665809 0.590 rs5001914 chr2:26415429 A/G cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.58e-9 Gut microbiome composition (summer); TGCT trans rs2688608 0.934 rs2675679 chr10:75658581 C/T cg13918328 chr10:52500089 ASAH2B 0.65 6.73 0.52 5.7e-10 Inflammatory bowel disease; TGCT cis rs4788570 0.615 rs7195059 chr16:71718366 C/T cg06353428 chr16:71660113 MARVELD3 1.56 12.54 0.75 8.54e-24 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.844 rs2424703 chr20:25270124 G/A cg03522245 chr20:25566470 NINL 0.55 5.55 0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2070488 0.775 rs1073506 chr3:38566235 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.68 -6.68 -0.51 7.13e-10 Electrocardiographic conduction measures; TGCT cis rs4665809 0.652 rs10779956 chr2:26405985 A/G cg04944784 chr2:26401820 FAM59B -0.8 -6.76 -0.52 4.91e-10 Gut microbiome composition (summer); TGCT cis rs2228479 0.850 rs11640336 chr16:89941153 T/C cg06558623 chr16:89946397 TCF25 0.59 6.77 0.52 4.66e-10 Skin colour saturation; TGCT cis rs5769707 0.740 rs79946167 chr22:50017556 G/A cg05373962 chr22:49881684 NA -0.24 -4.68 -0.39 7.44e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9916302 0.904 rs9904334 chr17:37468336 G/A cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs6074578 0.679 rs6086162 chr20:136025 C/T cg16931068 chr20:139680 DEFB127 0.3 5.28 0.43 5.62e-7 Hirschsprung disease; TGCT cis rs8103278 0.507 rs7260651 chr19:46260245 G/A cg11657440 chr19:46296263 DMWD 0.74 7.75 0.57 2.84e-12 Coronary artery disease; TGCT cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4478858 0.735 rs12134484 chr1:31823741 G/A cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs11626933 1.000 rs11626016 chr14:90747979 C/T cg14092571 chr14:90743983 NA -0.3 -6.18 -0.48 8.66e-9 Gut microbiota (bacterial taxa); TGCT cis rs644799 1.000 rs1944074 chr11:95511445 C/A cg03916912 chr11:95522834 CEP57;FAM76B 0.91 11.08 0.71 2.9e-20 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs17376456 0.877 rs10476598 chr5:93367281 C/T cg09848695 chr5:92956644 FAM172A;MIR2277 -0.67 -4.85 -0.4 3.66e-6 Diabetic retinopathy; TGCT cis rs9611519 0.929 rs9611465 chr22:41426139 G/A cg03806693 chr22:41940476 POLR3H -0.7 -6.22 -0.49 6.88e-9 Neuroticism; TGCT cis rs2235642 0.826 rs8048410 chr16:1614097 A/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.31 -5.21 -0.42 7.72e-7 Coronary artery disease; TGCT cis rs250677 0.687 rs250678 chr5:148434830 C/T cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT trans rs7824557 0.547 rs2409745 chr8:11076635 G/T cg06636001 chr8:8085503 FLJ10661 0.75 7.04 0.53 1.14e-10 Retinal vascular caliber; TGCT cis rs9393692 0.905 rs7450556 chr6:26299900 C/T cg05868516 chr6:26286170 HIST1H4H 0.63 5.93 0.47 2.76e-8 Educational attainment; TGCT trans rs1974653 0.672 rs9606248 chr22:20087539 A/G cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs12134245 0.776 rs12137878 chr1:91973210 G/T cg07090678 chr1:91966139 CDC7 0.37 5.05 0.41 1.56e-6 Breast cancer; TGCT cis rs922182 0.578 rs4776266 chr15:64236175 T/G cg02919090 chr15:64263738 DAPK2 -0.33 -6.14 -0.48 1.05e-8 Blood protein levels; TGCT cis rs2033711 0.755 rs4801587 chr19:58936679 C/A cg13877915 chr19:58951672 ZNF132 0.88 11.14 0.71 2.09e-20 Uric acid clearance; TGCT cis rs875971 1.000 rs55962648 chr7:65625751 C/G cg18876405 chr7:65276391 NA -0.33 -4.99 -0.41 1.97e-6 Aortic root size; TGCT cis rs9611519 1.000 rs3818003 chr22:41609690 C/T cg13695892 chr22:41940480 POLR3H -0.51 -4.71 -0.39 6.49e-6 Neuroticism; TGCT cis rs7666738 0.791 rs6851549 chr4:99029827 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.867 rs2584702 chr15:43684914 C/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.12 0.59 4.02e-13 Lung cancer in ever smokers; TGCT cis rs13108904 0.934 rs13115173 chr4:1316824 T/C cg13395646 chr4:1353034 KIAA1530 -0.47 -6.15 -0.48 9.8e-9 Obesity-related traits; TGCT cis rs2243480 0.831 rs57294491 chr7:65684901 T/A cg20637647 chr7:64974828 NA -0.91 -5.01 -0.41 1.82e-6 Diabetic kidney disease; TGCT cis rs42648 0.869 rs10234301 chr7:89918278 T/C cg25739043 chr7:89950458 NA -0.75 -7.35 -0.55 2.29e-11 Homocysteine levels; TGCT cis rs10504229 1.000 rs75037501 chr8:58170136 T/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs3806843 0.521 rs192231 chr5:140248539 C/T cg09824255 chr5:140014002 CD14 -0.26 -4.64 -0.38 8.65e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs7772486 0.846 rs6908063 chr6:146403618 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2013441 0.931 rs4925089 chr17:20064784 A/T cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs7216064 1.000 rs8079754 chr17:65887896 A/G cg12091567 chr17:66097778 LOC651250 -0.84 -6.58 -0.51 1.18e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs71435601 0.506 rs547235 chr2:21384682 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs782590 0.967 rs2627759 chr2:55853341 T/C cg18811423 chr2:55921094 PNPT1 0.67 7.1 0.54 8.63e-11 Metabolic syndrome; TGCT cis rs112217694 1.000 rs78289308 chr4:104643796 A/T cg24090629 chr4:104641072 TACR3 -1.0 -5.19 -0.42 8.44e-7 Menarche (age at onset); TGCT cis rs10510102 0.808 rs12253007 chr10:123698875 G/A cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs3540 0.513 rs12905756 chr15:90924047 C/T cg22089800 chr15:90895588 ZNF774 0.82 9.04 0.63 2.61e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT trans rs7618501 0.699 rs2681781 chr3:49898273 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.91 10.04 0.67 1.04e-17 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.673 rs7434391 chr4:9967682 C/G cg00071950 chr4:10020882 SLC2A9 -0.57 -6.83 -0.52 3.47e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs56114371 0.777 rs200483 chr6:27774824 C/T cg10876282 chr6:28092338 ZSCAN16 0.76 4.53 0.38 1.35e-5 Breast cancer; TGCT cis rs7666738 0.830 rs9995370 chr4:98732145 T/G cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7236492 0.572 rs112024357 chr18:77175610 T/C cg15644404 chr18:77186268 NFATC1 -0.43 -4.5 -0.37 1.57e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7119038 0.818 rs6589685 chr11:118612197 T/C cg19308663 chr11:118741387 NA 0.22 4.56 0.38 1.22e-5 Sjögren's syndrome; TGCT cis rs2067615 0.579 rs3782709 chr12:107205753 A/G cg15890332 chr12:107067104 RFX4 0.23 4.44 0.37 1.98e-5 Heart rate; TGCT cis rs7811142 0.779 rs28680963 chr7:99905475 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.44 -0.6 6.87e-14 Platelet count; TGCT cis rs137699 0.652 rs2413589 chr22:39755689 C/T cg11247378 chr22:39784982 NA 0.51 5.62 0.45 1.22e-7 IgG glycosylation; TGCT cis rs7829975 0.681 rs2271342 chr8:8643938 C/T cg08975724 chr8:8085496 FLJ10661 0.56 4.91 0.4 2.85e-6 Mood instability; TGCT cis rs10504229 0.683 rs11774697 chr8:58133119 G/A cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs3741489 1.000 rs4758889 chr12:133475533 C/T cg08320014 chr12:133707169 ZNF10 -1.3 -4.52 -0.38 1.41e-5 Cognitive function; TGCT cis rs1218582 0.596 rs906595 chr1:154822907 C/T cg16680214 chr1:154839983 KCNN3 -0.26 -4.91 -0.4 2.8e-6 Prostate cancer; TGCT cis rs3733585 0.699 rs6839490 chr4:9965000 C/G cg00071950 chr4:10020882 SLC2A9 0.46 4.87 0.4 3.26e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7975161 0.630 rs6539131 chr12:104644697 A/G cg25273343 chr12:104657179 TXNRD1 -0.47 -5.85 -0.46 4.13e-8 Toenail selenium levels; TGCT cis rs7944584 0.655 rs2856653 chr11:47361084 T/C cg20307385 chr11:47447363 PSMC3 -0.79 -7.99 -0.58 8.1e-13 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs6700896 0.500 rs11208692 chr1:66107946 A/C cg14976592 chr1:65886160 LEPROT;LEPR 0.58 4.53 0.38 1.35e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs1008375 1.000 rs10939750 chr4:17692422 C/G cg18681998 chr4:17616180 MED28 0.77 7.32 0.55 2.7e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1372520 0.567 rs2619349 chr4:90746646 G/T cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs10411936 1.000 rs10411936 chr19:16548375 C/T cg14704714 chr19:15740395 CYP4F8 -0.26 -4.59 -0.38 1.06e-5 White blood cell count;Multiple sclerosis; TGCT cis rs1775715 0.707 rs2778669 chr10:32161541 C/T cg14930904 chr10:32216787 ARHGAP12 0.54 5.3 0.43 5.12e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6701037 0.566 rs1014555 chr1:175134249 C/T cg00321850 chr1:175162397 KIAA0040 0.38 5.04 0.41 1.61e-6 Alcohol dependence; TGCT cis rs56104184 0.887 rs4801778 chr19:49370609 G/T cg21252483 chr19:49399788 TULP2 -0.33 -5.2 -0.42 7.94e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4072705 0.967 rs4076333 chr9:127385609 A/G cg13476313 chr9:127244764 NR5A1 0.28 4.66 0.39 7.99e-6 Menarche (age at onset); TGCT cis rs968451 0.865 rs12627761 chr22:39724137 A/G cg17798944 chr22:39715225 SNORD43;RPL3 -0.87 -8.73 -0.62 1.46e-14 Primary biliary cholangitis; TGCT cis rs12950390 0.853 rs17773010 chr17:45858297 C/T cg06532163 chr17:45867833 NA 0.37 5.89 0.47 3.46e-8 IgG glycosylation; TGCT cis rs67311347 1.000 rs4246666 chr3:40407670 C/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs73110464 0.505 rs2682296 chr12:53308265 G/A cg25025879 chr12:53359317 NA -0.39 -5.08 -0.42 1.35e-6 Cancer (pleiotropy); TGCT cis rs13118159 0.505 rs1250128 chr4:1257311 T/C cg16405210 chr4:1374714 KIAA1530 0.24 4.52 0.38 1.41e-5 Longevity; TGCT cis rs4499344 0.521 rs1862214 chr19:33035849 C/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.65 5.68 0.45 9.08e-8 Mean platelet volume; TGCT cis rs7216064 0.861 rs73352810 chr17:65875184 G/A cg12091567 chr17:66097778 LOC651250 -0.87 -6.85 -0.52 3.1e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2836950 0.565 rs2836930 chr21:40545656 A/G cg11644478 chr21:40555479 PSMG1 -0.54 -4.89 -0.4 3.02e-6 Menarche (age at onset); TGCT cis rs9311474 0.575 rs4434138 chr3:52556890 A/G cg10802521 chr3:52805072 NEK4 -0.72 -8.65 -0.61 2.18e-14 Electroencephalogram traits; TGCT cis rs7267979 0.844 rs6107017 chr20:25232300 A/G cg03522245 chr20:25566470 NINL 0.57 5.67 0.45 9.54e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10256972 0.552 rs2949192 chr7:1203841 C/T cg17775962 chr7:1200435 ZFAND2A 0.28 4.84 0.4 3.78e-6 Longevity;Endometriosis; TGCT cis rs28386778 0.901 rs2665855 chr17:61965143 A/G cg11494091 chr17:61959527 GH2 0.6 13.05 0.76 5.09e-25 Prudent dietary pattern; TGCT cis rs9928842 0.823 rs4888365 chr16:75282247 A/G cg09066997 chr16:75300724 BCAR1 0.27 4.72 0.39 6.16e-6 Alcoholic chronic pancreatitis; TGCT cis rs9534288 0.797 rs2094246 chr13:46602163 C/T cg15192986 chr13:46630673 CPB2 -0.52 -7.53 -0.56 9.22e-12 Blood protein levels; TGCT cis rs473651 0.692 rs579511 chr2:239334914 C/G cg08773314 chr2:239334832 ASB1 0.48 8.09 0.59 4.68e-13 Multiple system atrophy; TGCT cis rs9303542 0.625 rs4239209 chr17:46574317 T/A cg25032089 chr17:46643351 HOXB3 -0.51 -5.59 -0.45 1.35e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs9291683 0.679 rs13137795 chr4:10051506 G/A cg11266682 chr4:10021025 SLC2A9 0.65 8.7 0.62 1.74e-14 Bone mineral density; TGCT cis rs9291683 0.679 rs3756225 chr4:10094133 G/C cg00071950 chr4:10020882 SLC2A9 -0.51 -5.68 -0.45 9.25e-8 Bone mineral density; TGCT cis rs8031584 0.651 rs28664821 chr15:31172323 G/A cg14829155 chr15:31115871 NA 0.34 4.49 0.37 1.63e-5 Huntington's disease progression; TGCT cis rs7264396 0.635 rs2425166 chr20:34439391 G/A cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs9372498 0.572 rs62422230 chr6:118959436 T/C cg07617317 chr6:118971624 C6orf204 0.47 4.95 0.41 2.33e-6 Diastolic blood pressure; TGCT cis rs35146811 0.771 rs6465762 chr7:99620554 G/A cg13334819 chr7:99746414 C7orf59 -0.82 -7.38 -0.55 2.05e-11 Coronary artery disease; TGCT cis rs9467711 0.659 rs35433030 chr6:26529890 G/A cg16898833 chr6:26189333 HIST1H4D 1.25 5.86 0.47 3.88e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs7811142 1.000 rs4989959 chr7:100032288 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs6534347 0.613 rs6848834 chr4:123509713 T/G cg10583651 chr4:123538969 IL21 -0.32 -4.49 -0.37 1.63e-5 Type 1 diabetes; TGCT cis rs2070488 1.000 rs1002676 chr3:38444932 A/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.88 -9.55 -0.65 1.58e-16 Electrocardiographic conduction measures; TGCT cis rs2439831 1.000 rs2245908 chr15:43731454 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg20052079 chr6:15504923 JARID2 0.96 5.6 0.45 1.31e-7 Gambling; TGCT cis rs7267979 0.714 rs3787082 chr20:25235736 A/T cg03522245 chr20:25566470 NINL 0.48 4.59 0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7615952 0.736 rs11921945 chr3:125643719 A/G cg07211511 chr3:129823064 LOC729375 -0.47 -7.89 -0.58 1.37e-12 Blood pressure (smoking interaction); TGCT trans rs208520 0.690 rs12208310 chr6:66730108 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 1.0 11.06 0.7 3.28e-20 Exhaled nitric oxide output; TGCT cis rs6570726 0.791 rs370654 chr6:145879005 C/G cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.568 rs4816620 chr21:40613786 A/G cg11644478 chr21:40555479 PSMG1 -0.62 -5.84 -0.46 4.38e-8 Cognitive function; TGCT cis rs1401999 1.000 rs939338 chr3:183704068 A/G cg01324343 chr3:183735012 ABCC5 -0.82 -10.58 -0.69 4.84e-19 Anterior chamber depth; TGCT cis rs7829975 0.660 rs10093926 chr8:8549020 A/C cg15556689 chr8:8085844 FLJ10661 -0.71 -6.29 -0.49 4.97e-9 Mood instability; TGCT cis rs2688608 0.530 rs71507081 chr10:75493136 G/A cg04320760 chr10:75533139 FUT11 -0.4 -6.25 -0.49 6.11e-9 Inflammatory bowel disease; TGCT cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs6933660 0.683 rs8180642 chr6:151756612 A/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.9 -9.68 -0.66 7.45e-17 Menarche (age at onset); TGCT cis rs2404602 0.536 rs11072599 chr15:76774508 T/C cg26408565 chr15:76604113 ETFA -0.37 -4.97 -0.41 2.13e-6 Blood metabolite levels; TGCT cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg23758822 chr17:41437982 NA 0.67 6.77 0.52 4.65e-10 Menopause (age at onset); TGCT cis rs17122693 1.000 rs3759588 chr14:51062357 G/A cg04730355 chr14:51134070 SAV1 1.21 8.51 0.61 4.69e-14 Cognitive performance; TGCT cis rs514406 0.798 rs576650 chr1:53327207 C/T cg27535305 chr1:53392650 SCP2 -0.27 -5.29 -0.43 5.24e-7 Monocyte count; TGCT cis rs9911578 1.000 rs8071280 chr17:57010225 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs17433780 0.808 rs1074541 chr1:89509499 A/G cg09516651 chr1:89888402 LOC400759 0.26 4.94 0.41 2.48e-6 Carotid intima media thickness; TGCT cis rs739496 0.615 rs630616 chr12:112158966 T/C cg10833066 chr12:111807467 FAM109A 0.37 4.79 0.39 4.76e-6 Platelet count; TGCT trans rs12001652 0.579 rs12001843 chr9:14018558 C/G cg16456503 chr16:67943052 PSKH1 0.43 6.62 0.51 9.91e-10 Carotid plaque burden; TGCT cis rs7635838 0.859 rs34621655 chr3:11530121 T/C cg00170343 chr3:11313890 ATG7 0.71 6.74 0.52 5.41e-10 HDL cholesterol; TGCT cis rs7635838 0.722 rs2594982 chr3:11379958 C/T cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs7659604 0.539 rs11098645 chr4:122729251 G/A cg06713675 chr4:122721982 EXOSC9 -0.69 -9.69 -0.66 7.11e-17 Type 2 diabetes; TGCT cis rs9297145 0.585 rs17147666 chr7:98781457 A/C cg05967295 chr7:98741636 SMURF1 -0.68 -8.35 -0.6 1.12e-13 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs10779751 0.922 rs2746638 chr1:11278125 T/C cg08854313 chr1:11322531 MTOR 0.96 8.74 0.62 1.37e-14 Body mass index; TGCT cis rs9486715 0.867 rs9373907 chr6:96981189 G/A cg18709589 chr6:96969512 KIAA0776 0.78 7.61 0.56 6.08e-12 Headache; TGCT cis rs10984561 1.000 rs57411773 chr9:122252587 T/A cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12477438 0.520 rs1133978 chr2:99741964 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs7824557 0.564 rs2736294 chr8:11234626 T/C cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.97e-9 Retinal vascular caliber; TGCT cis rs1018836 0.628 rs35816262 chr8:91511017 C/G cg16814680 chr8:91681699 NA -0.84 -8.45 -0.6 6.52e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2070488 0.736 rs2070988 chr3:38437835 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.73 6.03 0.48 1.73e-8 Electrocardiographic conduction measures; TGCT cis rs911555 0.546 rs28798508 chr14:104068970 T/C cg26031613 chr14:104095156 KLC1 0.61 5.6 0.45 1.34e-7 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.530 rs7036833 chr9:5226484 G/A cg02405213 chr9:5042618 JAK2 -0.66 -8.18 -0.59 2.88e-13 Pediatric autoimmune diseases; TGCT cis rs1670533 1.000 rs688785 chr4:1082707 G/C cg20887711 chr4:1340912 KIAA1530 0.68 5.33 0.43 4.53e-7 Recombination rate (females); TGCT cis rs1008375 1.000 rs114490726 chr4:17680898 T/C cg10189774 chr4:17578691 LAP3 0.56 5.25 0.43 6.39e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10832963 1.000 rs11024739 chr11:18645843 A/C cg09201001 chr11:18656081 SPTY2D1 -1.04 -11.69 -0.72 9.87e-22 Breast cancer; TGCT cis rs896854 0.654 rs2011566 chr8:95971921 G/A cg13393036 chr8:95962371 TP53INP1 -0.59 -8.06 -0.59 5.59e-13 Type 2 diabetes; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs7833790 0.963 rs7836040 chr8:82698328 G/A cg17211192 chr8:82754475 SNX16 -1.05 -8.28 -0.6 1.63e-13 Diastolic blood pressure; TGCT cis rs74233809 1.000 rs11191560 chr10:104869038 A/G cg05855489 chr10:104503620 C10orf26 0.84 4.47 0.37 1.71e-5 Birth weight; TGCT cis rs61990749 0.597 rs4632066 chr14:78247282 C/T cg02301378 chr14:78227641 SNW1;C14orf178 -0.61 -4.52 -0.38 1.43e-5 Fibroblast growth factor basic levels; TGCT cis rs6424115 0.594 rs7519640 chr1:24069637 G/C cg15997130 chr1:24165203 NA 0.62 6.36 0.5 3.5e-9 Immature fraction of reticulocytes; TGCT cis rs1116547 0.684 rs2091804 chr5:112578507 A/G cg04138046 chr5:112608004 MCC -0.46 -4.65 -0.39 8.46e-6 Cerebral amyloid angiopathy; TGCT cis rs796364 0.806 rs4673634 chr2:200863349 A/C cg17644776 chr2:200775616 C2orf69 0.33 5.0 0.41 1.91e-6 Schizophrenia; TGCT cis rs1971762 0.527 rs4759211 chr12:53930945 T/C cg16917193 chr12:54089295 NA 1.02 10.39 0.68 1.44e-18 Height; TGCT cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs9467773 1.000 rs9393731 chr6:26529374 C/T cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs8176310 chr17:41199913 T/C cg23758822 chr17:41437982 NA 0.68 6.76 0.52 4.84e-10 Menopause (age at onset); TGCT cis rs7829975 0.557 rs7816427 chr8:8545884 T/C cg17143192 chr8:8559678 CLDN23 -0.52 -5.29 -0.43 5.45e-7 Mood instability; TGCT cis rs7772486 0.754 rs9497419 chr6:146142609 T/C cg23711669 chr6:146136114 FBXO30 0.9 10.15 0.67 5.45e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs7220711 1.000 rs12602349 chr17:41792236 T/C cg26893861 chr17:41843967 DUSP3 0.5 4.49 0.37 1.63e-5 Bone mineral density (spine);Bone mineral density (hip); TGCT cis rs6977955 1.000 rs4722762 chr7:28178262 G/T cg23620719 chr7:28220237 JAZF1 0.64 4.82 0.4 4.13e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs13191362 1.000 rs73016459 chr6:163066323 C/A cg21926612 chr6:163149169 PACRG;PARK2 1.06 8.12 0.59 3.96e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7552404 1.000 rs4559448 chr1:76203456 A/G cg10523679 chr1:76189770 ACADM 0.9 9.71 0.66 6.5e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs35771425 0.642 rs3767380 chr1:211452845 A/G cg25617285 chr1:211431773 RCOR3 -0.48 -5.48 -0.44 2.27e-7 Educational attainment (years of education); TGCT cis rs5769765 0.908 rs138880 chr22:50218611 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.06 -11.49 -0.72 2.94e-21 Schizophrenia; TGCT cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg11301795 chr4:187892539 NA -0.3 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs35306767 0.953 rs12259338 chr10:969377 C/T cg26597838 chr10:835615 NA 0.63 9.0 0.63 3.31e-15 Eosinophil percentage of granulocytes; TGCT cis rs9929218 0.953 rs12930910 chr16:68762520 A/G cg01251360 chr16:68772225 CDH1 0.29 4.95 0.41 2.34e-6 Colorectal cancer; TGCT cis rs6500602 0.647 rs4785967 chr16:4523208 G/A cg08645402 chr16:4508243 NA 0.18 4.99 0.41 1.98e-6 Schizophrenia; TGCT cis rs9303542 0.694 rs8071207 chr17:46584016 T/C cg25032089 chr17:46643351 HOXB3 -0.52 -5.82 -0.46 4.61e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs208515 0.525 rs1351866 chr6:66696969 A/G cg07460842 chr6:66804631 NA 0.88 9.36 0.64 4.39e-16 Exhaled nitric oxide levels; TGCT cis rs4733781 1.000 rs2033059 chr8:131271216 A/G cg16277922 chr8:131349729 ASAP1 -0.44 -5.56 -0.45 1.55e-7 Tuberculosis; TGCT cis rs7552404 0.924 rs7535991 chr1:76162624 C/T cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7647973 1.000 rs13096474 chr3:49443081 C/T cg05785598 chr3:49045655 WDR6 -0.39 -4.75 -0.39 5.56e-6 Menarche (age at onset); TGCT cis rs8180040 0.676 rs1108301 chr3:47029426 G/A cg27129171 chr3:47204927 SETD2 -0.72 -8.83 -0.62 8.21e-15 Colorectal cancer; TGCT cis rs2019137 0.539 rs4849181 chr2:113991970 A/G cg11763394 chr2:113992921 PAX8;LOC440839;LOC654433 0.44 4.66 0.39 7.86e-6 Lymphocyte counts; TGCT cis rs7552404 1.000 rs1498315 chr1:76159225 G/A cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs75686122 0.892 rs80350345 chr8:104608845 G/A cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs16867321 0.671 rs1544848 chr2:181487422 A/G cg23363182 chr2:181467187 NA -0.47 -4.85 -0.4 3.65e-6 Obesity; TGCT cis rs1153858 0.725 rs74572151 chr15:45647526 T/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs62064224 0.589 rs4523973 chr17:30809455 G/A cg18200150 chr17:30822561 MYO1D 0.42 4.99 0.41 2.02e-6 Schizophrenia; TGCT cis rs3749237 0.595 rs7637999 chr3:49535115 C/T cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs17122693 0.748 rs72679598 chr14:51107157 C/G cg04730355 chr14:51134070 SAV1 1.33 10.78 0.7 1.59e-19 Cognitive performance; TGCT cis rs10186029 0.676 rs10932465 chr2:213968389 T/C cg08319019 chr2:214017104 IKZF2 0.63 5.79 0.46 5.4e-8 Systemic sclerosis; TGCT cis rs12762955 0.561 rs10752022 chr10:1043798 C/T cg20503657 chr10:835505 NA -0.4 -5.21 -0.42 7.61e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs881375 0.967 rs758959 chr9:123676699 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.78 0.39 4.84e-6 Rheumatoid arthritis; TGCT cis rs6089829 0.962 rs2277769 chr20:61666805 C/T cg08045932 chr20:61659980 NA 0.47 8.93 0.63 4.84e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs4494114 0.967 rs9438986 chr1:39369652 T/G cg25970120 chr1:39325951 RRAGC -0.6 -6.32 -0.49 4.21e-9 Blood protein levels; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg24846343 chr22:24311635 DDTL -0.23 -5.85 -0.46 4.19e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10540 0.730 rs61876338 chr11:493730 A/G cg03934478 chr11:495069 RNH1 0.36 5.88 0.47 3.58e-8 Body mass index; TGCT cis rs9393692 0.905 rs4412192 chr6:26290377 A/G cg05868516 chr6:26286170 HIST1H4H -0.56 -5.35 -0.43 4.01e-7 Educational attainment; TGCT cis rs9952991 0.941 rs7237497 chr18:12777325 T/C cg24737193 chr18:12778029 NA 0.54 6.03 0.48 1.76e-8 Inflammatory skin disease; TGCT cis rs6964587 1.000 rs7797369 chr7:91570615 C/A cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs394563 0.726 rs6922130 chr6:149672375 C/G cg03678062 chr6:149772716 ZC3H12D 0.41 5.3 0.43 5.09e-7 Dupuytren's disease; TGCT cis rs3784262 0.904 rs4646620 chr15:58258241 G/A cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.59 -0.56 6.66e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2439831 0.850 rs28476182 chr15:44139643 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs42648 0.869 rs42617 chr7:89952046 T/A cg25739043 chr7:89950458 NA -0.68 -6.84 -0.52 3.2e-10 Homocysteine levels; TGCT cis rs3733585 0.579 rs4235356 chr4:10123106 G/C cg11266682 chr4:10021025 SLC2A9 -0.55 -6.41 -0.5 2.69e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1801251 1.000 rs7558609 chr2:233700379 C/T cg25237894 chr2:233734115 C2orf82 0.33 5.98 0.47 2.18e-8 Coronary artery disease; TGCT cis rs9325144 0.505 rs7955162 chr12:38711658 G/A cg13010199 chr12:38710504 ALG10B 0.66 5.16 0.42 9.36e-7 Morning vs. evening chronotype; TGCT cis rs881375 0.715 rs7858209 chr9:123645760 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.79e-7 Rheumatoid arthritis; TGCT cis rs8072100 0.790 rs1962307 chr17:45707871 A/G cg10024583 chr17:45772800 TBKBP1 0.48 4.86 0.4 3.53e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4742903 0.967 rs2274725 chr9:106864570 C/T cg21169611 chr9:106856078 SMC2 0.49 4.6 0.38 1.03e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs1799949 1.000 rs35330014 chr17:41212547 C/T cg05368731 chr17:41323189 NBR1 1.12 11.33 0.71 7.16e-21 Menopause (age at onset); TGCT cis rs9467773 0.587 rs3208733 chr6:26414425 C/T cg05738196 chr6:26577821 NA -0.52 -5.52 -0.44 1.89e-7 Intelligence (multi-trait analysis); TGCT cis rs2230307 0.518 rs2810425 chr1:100665072 G/C cg24955406 chr1:100503596 HIAT1 -0.7 -4.72 -0.39 6.32e-6 Carotid intima media thickness; TGCT cis rs4929949 0.752 rs4758067 chr11:8493429 C/T cg12906748 chr11:8954576 C11orf16 0.34 4.52 0.38 1.43e-5 Body mass index; TGCT cis rs916888 0.821 rs199509 chr17:44858728 G/A cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4819052 0.851 rs2838845 chr21:46670812 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.8 6.76 0.52 4.71e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs861020 1.000 rs12134698 chr1:209987801 C/A cg05527609 chr1:210001259 C1orf107 -0.91 -7.4 -0.55 1.84e-11 Orofacial clefts; TGCT cis rs12497850 0.805 rs11130176 chr3:48844077 A/G cg06212747 chr3:49208901 KLHDC8B 0.62 5.83 0.46 4.42e-8 Parkinson's disease; TGCT cis rs8180040 0.967 rs4858890 chr3:47405456 A/G cg27129171 chr3:47204927 SETD2 -0.68 -7.94 -0.58 1.01e-12 Colorectal cancer; TGCT cis rs9311474 0.607 rs4234633 chr3:52557038 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.74 0.52 5.28e-10 Electroencephalogram traits; TGCT cis rs2657888 0.899 rs7300877 chr12:56933233 C/A cg23002907 chr12:56915593 RBMS2 0.44 6.14 0.48 1.03e-8 Adiponectin levels; TGCT cis rs7666738 0.830 rs10028505 chr4:98962310 C/A cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6546537 1.000 rs6727435 chr2:69864236 C/A cg10773587 chr2:69614142 GFPT1 -0.71 -6.21 -0.49 7.48e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs910316 1.000 rs9805979 chr14:75566209 G/A cg11812906 chr14:75593930 NEK9 0.74 7.25 0.55 3.9e-11 Height; TGCT cis rs3784262 0.967 rs12910752 chr15:58314679 G/A cg12031962 chr15:58353849 ALDH1A2 -0.52 -7.93 -0.58 1.1e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs11249608 0.548 rs2132672 chr5:178457742 A/C cg23951258 chr5:178450506 ZNF879 0.44 4.56 0.38 1.22e-5 Pubertal anthropometrics; TGCT cis rs13401104 0.587 rs7569760 chr2:237145713 A/C cg19324714 chr2:237145437 ASB18 0.48 5.03 0.41 1.67e-6 Educational attainment; TGCT cis rs950169 0.845 rs4502182 chr15:84923520 A/G cg12863693 chr15:85201151 NMB 0.41 4.5 0.38 1.51e-5 Schizophrenia; TGCT cis rs79349575 0.716 rs46522 chr17:46988597 C/T cg07967210 chr17:47022446 SNF8 0.44 6.21 0.49 7.17e-9 Type 2 diabetes; TGCT cis rs873946 0.689 rs2803993 chr10:134550606 T/C cg27286337 chr10:134555280 INPP5A 0.44 5.4 0.44 3.27e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9486719 0.690 rs2092094 chr6:96844123 G/C cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs6598955 0.572 rs6598951 chr1:26592714 G/T cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs7000551 0.715 rs2469745 chr8:22343464 C/T cg12081754 chr8:22256438 SLC39A14 0.31 5.09 0.42 1.29e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9467603 1.000 rs13201341 chr6:25822661 C/T cg16898833 chr6:26189333 HIST1H4D 1.38 6.09 0.48 1.31e-8 Intelligence (multi-trait analysis); TGCT cis rs9399401 0.667 rs6903424 chr6:142699948 A/C cg04461802 chr6:142623433 GPR126 0.46 4.66 0.39 8.04e-6 Chronic obstructive pulmonary disease; TGCT cis rs6088590 1.000 rs10048849 chr20:33419680 C/T cg24642439 chr20:33292090 TP53INP2 0.68 5.92 0.47 2.93e-8 Coronary artery disease; TGCT cis rs473651 0.692 rs579511 chr2:239334914 C/G cg21699342 chr2:239360505 ASB1 0.19 5.43 0.44 2.87e-7 Multiple system atrophy; TGCT cis rs7829975 0.774 rs13259216 chr8:8673601 A/C cg08975724 chr8:8085496 FLJ10661 0.53 4.76 0.39 5.29e-6 Mood instability; TGCT cis rs7267979 0.844 rs869358 chr20:25374674 A/G cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg09222892 chr1:25734099 RHCE -0.43 -7.1 -0.54 8.54e-11 Plateletcrit;Mean corpuscular volume; TGCT cis rs1862618 0.802 rs7733041 chr5:56107377 A/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.78 -0.52 4.3e-10 Initial pursuit acceleration; TGCT cis rs910187 0.624 rs6066219 chr20:45793967 A/T cg27589058 chr20:45804311 EYA2 -0.34 -6.81 -0.52 3.81e-10 Migraine; TGCT cis rs77972916 0.505 rs34247383 chr2:43532780 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -5.49 -0.44 2.18e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs8014252 0.803 rs73282127 chr14:70986413 T/C cg11204974 chr14:71022665 NA -0.53 -4.46 -0.37 1.79e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs7714584 1.000 rs10463307 chr5:150254620 C/T cg22134413 chr5:150180641 NA 0.89 6.87 0.53 2.72e-10 Crohn's disease; TGCT cis rs7804356 1.000 rs3801844 chr7:26829759 C/T cg03456212 chr7:26904342 SKAP2 0.63 4.83 0.4 3.98e-6 Type 1 diabetes; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg17178900 chr1:205818956 PM20D1 0.6 7.63 0.57 5.3e-12 Menarche (age at onset); TGCT cis rs858239 0.600 rs10266123 chr7:23136487 G/C cg05602783 chr7:23145260 KLHL7 -0.71 -5.95 -0.47 2.52e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9393692 1.000 rs9393692 chr6:26276650 A/G cg00631329 chr6:26305371 NA -0.45 -6.9 -0.53 2.42e-10 Educational attainment; TGCT cis rs6500602 0.826 rs11076830 chr16:4460049 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 6.7 0.52 6.4e-10 Schizophrenia; TGCT cis rs12148488 0.738 rs4886417 chr15:75330159 T/G cg10253484 chr15:75165896 SCAMP2 -0.57 -4.95 -0.41 2.4e-6 Caffeine consumption; TGCT cis rs586688 1.000 rs492563 chr1:201631471 C/T cg07139329 chr1:201708558 NAV1 -0.45 -4.67 -0.39 7.6e-6 Obesity-related traits; TGCT cis rs11764590 0.950 rs62444919 chr7:2109499 C/T cg25834613 chr7:1915315 MAD1L1 -0.52 -5.04 -0.41 1.64e-6 Neuroticism; TGCT cis rs13223928 0.621 rs10228451 chr7:3150859 C/G cg19214707 chr7:3157722 NA 0.48 6.98 0.53 1.56e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs9486719 0.947 rs9398072 chr6:96911304 T/C cg18709589 chr6:96969512 KIAA0776 0.73 5.75 0.46 6.45e-8 Migraine;Coronary artery disease; TGCT cis rs8031584 0.781 rs4779498 chr15:31177476 C/T cg08109568 chr15:31115862 NA -0.4 -5.25 -0.43 6.5e-7 Huntington's disease progression; TGCT cis rs12142240 0.698 rs6667861 chr1:46815749 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs7726839 0.574 rs12522955 chr5:639231 C/A cg16624210 chr5:671434 TPPP 0.42 4.68 0.39 7.38e-6 Obesity-related traits; TGCT cis rs12701220 0.894 rs12701348 chr7:1039457 C/T cg07217954 chr7:1067459 C7orf50 -0.46 -4.65 -0.39 8.34e-6 Bronchopulmonary dysplasia; TGCT cis rs6952808 0.692 rs59619245 chr7:2068630 C/T cg04267008 chr7:1944627 MAD1L1 -0.4 -5.4 -0.44 3.25e-7 Bipolar disorder and schizophrenia; TGCT cis rs12579753 1.000 rs11115015 chr12:82174543 T/C cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg10108389 chr3:44770937 ZNF501 -0.47 -4.64 -0.38 8.9e-6 Depressive symptoms; TGCT cis rs9467711 0.651 rs55912630 chr6:25866935 T/C cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs9372253 1.000 rs7740028 chr6:110719180 A/G cg19196401 chr6:110721138 DDO -0.52 -7.56 -0.56 7.8e-12 Platelet distribution width; TGCT cis rs4843747 0.749 rs13333619 chr16:88072076 C/T cg06915872 chr16:87998081 BANP -0.3 -4.52 -0.38 1.44e-5 Menopause (age at onset); TGCT cis rs7666738 0.830 rs4699594 chr4:98980775 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs13138920 chr4:99020786 A/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs447921 0.768 rs34546420 chr17:74459602 C/A cg09812376 chr17:74270190 QRICH2 -0.46 -4.54 -0.38 1.3e-5 Mitochondrial DNA levels; TGCT trans rs11785693 0.909 rs62489557 chr8:4968371 A/G cg21607066 chr6:79787807 PHIP 0.91 6.8 0.52 3.93e-10 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs2302045 1.000 rs2302052 chr2:242063448 G/A cg04553960 chr2:241721320 KIF1A -0.69 -4.74 -0.39 5.8e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs7666738 0.830 rs991168 chr4:98928293 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9916302 0.800 rs8081220 chr17:37473157 A/C cg15445000 chr17:37608096 MED1 -0.35 -5.05 -0.41 1.53e-6 Glomerular filtration rate (creatinine); TGCT cis rs6671200 1.000 rs71654417 chr1:95661200 G/A cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs9914988 0.943 rs59461345 chr17:27151852 G/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs931127 0.719 rs11227259 chr11:65459404 T/C cg17480646 chr11:65405466 SIPA1 -0.43 -5.74 -0.46 6.76e-8 Systemic lupus erythematosus; TGCT cis rs7666738 0.830 rs7678557 chr4:99057329 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.607 rs11206000 chr1:53205923 A/C cg08859206 chr1:53392774 SCP2 0.35 5.04 0.41 1.62e-6 Monocyte count; TGCT cis rs597539 0.652 rs627731 chr11:68698663 A/C cg21963583 chr11:68658836 MRPL21 0.35 5.8 0.46 5.09e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs826838 0.967 rs1352122 chr12:39130885 G/A cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs1218582 0.772 rs4845688 chr1:154884142 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs71007656 1 rs71007656 chr10:37970845 CGGCTG/C cg25427524 chr10:38739819 LOC399744 -0.33 -6.48 -0.5 1.99e-9 Extrinsic epigenetic age acceleration; TGCT cis rs6459804 0.527 rs60688149 chr7:157533159 G/A cg11757124 chr7:157526947 PTPRN2 -0.46 -5.36 -0.43 3.87e-7 Bipolar disorder and schizophrenia; TGCT cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg09904177 chr6:26538194 HMGN4 0.68 6.27 0.49 5.41e-9 Intelligence (multi-trait analysis); TGCT cis rs11122272 0.701 rs11582413 chr1:231530098 C/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT cis rs9910055 0.762 rs7213436 chr17:42252163 A/G cg10896456 chr17:42255109 ASB16;C17orf65 -0.25 -4.47 -0.37 1.75e-5 Total body bone mineral density; TGCT trans rs561341 0.941 rs112569713 chr17:30271738 C/T cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs1062177 0.756 rs2915827 chr5:151119705 T/A cg12924095 chr5:151150029 G3BP1 -0.34 -4.97 -0.41 2.17e-6 Preschool internalizing problems; TGCT cis rs17001868 0.568 rs9611312 chr22:40734790 T/C cg07138101 chr22:40742427 ADSL 0.73 5.38 0.44 3.57e-7 Mammographic density (dense area); TGCT cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.96 -8.31 -0.6 1.43e-13 Platelet count; TGCT cis rs12484776 0.786 rs6001794 chr22:40529415 A/C cg07138101 chr22:40742427 ADSL -0.6 -4.84 -0.4 3.73e-6 Uterine fibroids; TGCT cis rs7833790 0.929 rs10958048 chr8:82792914 C/T cg27398817 chr8:82754497 SNX16 0.74 5.19 0.42 8.37e-7 Diastolic blood pressure; TGCT cis rs6840360 0.615 rs4696290 chr4:152631472 A/G cg17479576 chr4:152424074 FAM160A1 -0.53 -5.33 -0.43 4.47e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.924 rs3818855 chr1:76198785 C/T cg22875332 chr1:76189707 ACADM 0.76 9.36 0.64 4.49e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.830 rs62318472 chr4:98926030 G/A cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9388451 0.559 rs1777210 chr6:126098916 T/G cg05901451 chr6:126070800 HEY2 -0.94 -11.89 -0.73 3.1e-22 Brugada syndrome; TGCT cis rs6714788 0.565 rs9308833 chr2:100662618 C/T cg07810366 chr2:100720526 AFF3 -0.36 -5.28 -0.43 5.55e-7 Intelligence (multi-trait analysis); TGCT cis rs6558530 0.897 rs7838456 chr8:1707591 T/G cg09410841 chr8:1729607 CLN8 0.92 10.2 0.68 4.08e-18 Systolic blood pressure; TGCT cis rs4711350 1.000 rs10947436 chr6:33739960 A/G cg00334056 chr6:33755658 LEMD2 -0.29 -4.63 -0.38 9.08e-6 Schizophrenia; TGCT cis rs2777491 0.522 rs7173571 chr15:41712807 T/C cg18705301 chr15:41695430 NDUFAF1 -0.5 -7.0 -0.53 1.46e-10 Ulcerative colitis; TGCT cis rs2235642 0.787 rs2235646 chr16:1601287 A/G cg07341220 chr16:1583899 IFT140;TMEM204 -0.31 -4.88 -0.4 3.26e-6 Coronary artery disease; TGCT cis rs9486719 0.857 rs13208321 chr6:96860354 C/T cg18709589 chr6:96969512 KIAA0776 -0.69 -5.59 -0.45 1.38e-7 Migraine;Coronary artery disease; TGCT cis rs2404618 0.587 rs6994849 chr8:1492839 G/T cg13402656 chr8:1511478 DLGAP2 0.36 6.29 0.49 5.03e-9 Lung cancer; TGCT cis rs1483890 0.642 rs9825849 chr3:69404575 C/T cg22125112 chr3:69402811 FRMD4B 0.28 4.57 0.38 1.18e-5 Resting heart rate; TGCT cis rs12497850 0.931 rs11920534 chr3:48937761 G/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs3784262 1.000 rs7170896 chr15:58252393 T/A cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.79 -0.57 2.28e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs17293817 0.625 rs10794748 chr10:1421516 A/G cg19299265 chr10:1975631 NA -0.26 -4.5 -0.37 1.55e-5 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT trans rs9951602 0.512 rs9953258 chr18:76651199 A/C cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs6952808 0.636 rs60605830 chr7:1949198 A/G cg22963979 chr7:1858916 MAD1L1 -0.36 -5.49 -0.44 2.18e-7 Bipolar disorder and schizophrenia; TGCT cis rs33794 0.588 rs28295 chr3:45252249 G/A cg18645101 chr3:44551900 NA 0.51 4.55 0.38 1.26e-5 Lung function (forced expiratory volume in 1 second); TGCT cis rs17270561 1.000 rs12200962 chr6:25828986 T/C cg15022984 chr6:26056706 HIST1H1C -0.73 -4.6 -0.38 1.02e-5 Iron status biomarkers; TGCT cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg21724239 chr8:58056113 NA 0.4 5.07 0.41 1.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs765787 0.530 rs1706831 chr15:45516230 T/C cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs9883204 1.000 rs35841686 chr3:123087916 T/A cg04890266 chr3:123102914 ADCY5 0.34 4.74 0.39 5.7e-6 Birth weight; TGCT cis rs4803468 1.000 rs166925 chr19:41926098 T/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.57 -0.69 5.19e-19 Height; TGCT cis rs9611565 0.559 rs6002408 chr22:41967870 C/T cg03806693 chr22:41940476 POLR3H -1.07 -11.03 -0.7 4e-20 Vitiligo; TGCT cis rs595982 0.559 rs4802516 chr19:49366170 T/C cg21252483 chr19:49399788 TULP2 -0.42 -6.39 -0.5 3.02e-9 Red cell distribution width; TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg26354017 chr1:205819088 PM20D1 0.55 6.55 0.51 1.4e-9 Menarche (age at onset); TGCT cis rs9682041 0.627 rs4955722 chr3:170102959 G/T cg11886554 chr3:170076028 SKIL 0.62 4.82 0.4 4.11e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs875971 0.862 rs880166 chr7:65670762 T/C cg11764359 chr7:65958608 NA -0.57 -5.25 -0.43 6.43e-7 Aortic root size; TGCT cis rs2243480 0.803 rs36004293 chr7:65416512 T/C cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT trans rs916888 0.647 rs199523 chr17:44848517 C/A cg10053473 chr17:62856997 LRRC37A3 0.4 6.73 0.52 5.74e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1499614 1.000 rs2707832 chr7:66136549 C/T cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs1799949 1.000 rs12936831 chr17:41331816 C/T cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs7698623 1.000 rs7698623 chr4:88755828 A/G cg02735620 chr4:88950514 PKD2 -0.44 -4.6 -0.38 1.02e-5 Cardiovascular disease risk factors; TGCT cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg09222892 chr1:25734099 RHCE -0.42 -6.69 -0.52 6.75e-10 Erythrocyte sedimentation rate; TGCT cis rs6121246 0.567 rs6060295 chr20:30198473 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.17 -0.48 8.86e-9 Mean corpuscular hemoglobin; TGCT cis rs8013055 1.000 rs8013055 chr14:105990620 T/A cg19700328 chr14:106028568 NA -0.48 -4.93 -0.4 2.62e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs427394 0.659 rs274675 chr5:6755319 C/T cg10857441 chr5:6722123 POLS -0.32 -6.94 -0.53 1.95e-10 Menopause (age at onset); TGCT cis rs1692580 0.777 rs7547453 chr1:2195117 C/T cg21194808 chr1:2205498 SKI 0.29 5.59 0.45 1.38e-7 Coronary artery disease; TGCT cis rs9549367 0.865 rs3861721 chr13:113906308 C/T cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs910187 1.000 rs4555399 chr20:45837896 G/A cg27589058 chr20:45804311 EYA2 -0.32 -5.86 -0.47 3.86e-8 Migraine; TGCT cis rs2404602 0.692 rs34478400 chr15:76923510 C/T cg22467129 chr15:76604101 ETFA -0.44 -4.98 -0.41 2.07e-6 Blood metabolite levels; TGCT trans rs1814175 0.817 rs4881627 chr11:49953955 C/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.14 -0.54 6.88e-11 Height; TGCT cis rs9650657 0.585 rs4841401 chr8:10489592 C/G cg27411982 chr8:10470053 RP1L1 -0.23 -4.89 -0.4 3.03e-6 Neuroticism; TGCT cis rs2243480 1.000 rs781150 chr7:65480973 C/T cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs4237845 0.844 rs4630335 chr12:58302258 A/G cg02175503 chr12:58329896 NA 0.58 5.92 0.47 3e-8 Intelligence (multi-trait analysis); TGCT cis rs72615157 0.634 rs11762932 chr7:99792666 C/T cg00814883 chr7:100076585 TSC22D4 0.56 5.44 0.44 2.69e-7 Lung function (FEV1/FVC); TGCT cis rs240764 0.658 rs2132168 chr6:101178491 G/A cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.48e-5 Neuroticism; TGCT trans rs1005277 0.579 rs11011461 chr10:38431427 G/A cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs3617 0.573 rs9880978 chr3:52923251 C/G cg10802521 chr3:52805072 NEK4 -0.59 -6.71 -0.52 6.06e-10 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs11122272 0.766 rs2808608 chr1:231543175 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.71 -0.52 6.09e-10 Hemoglobin concentration; TGCT cis rs6089584 0.528 rs881994 chr20:60623931 G/A cg13770153 chr20:60521292 NA -0.43 -5.09 -0.42 1.3e-6 Body mass index; TGCT cis rs9902453 1.000 rs4465649 chr17:28394747 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.76 -6.7 -0.52 6.38e-10 Coffee consumption (cups per day); TGCT cis rs1903068 0.925 rs1551642 chr4:55994210 T/C cg01777861 chr4:56023843 NA 0.56 6.43 0.5 2.54e-9 Endometriosis; TGCT cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT trans rs3780486 0.846 rs7865745 chr9:33140976 A/G cg20290983 chr6:43655470 MRPS18A -1.11 -14.0 -0.78 2.68e-27 IgG glycosylation; TGCT cis rs12950390 0.853 rs4794107 chr17:45843159 T/G cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.6e-6 IgG glycosylation; TGCT cis rs7267979 1.000 rs2424716 chr20:25423538 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs950776 0.714 rs472054 chr15:78887994 A/G cg06917634 chr15:78832804 PSMA4 -0.65 -5.33 -0.43 4.48e-7 Sudden cardiac arrest; TGCT cis rs2243480 0.803 rs35480979 chr7:65357084 A/G cg07424592 chr7:64974309 NA 1.36 8.15 0.59 3.36e-13 Diabetic kidney disease; TGCT cis rs12188164 0.686 rs72711365 chr5:416672 G/A cg22025206 chr5:502436 SLC9A3 -0.26 -4.69 -0.39 7.2e-6 Cystic fibrosis severity; TGCT cis rs904251 0.523 rs1776454 chr6:37482099 C/T cg01843034 chr6:37503916 NA -0.56 -7.56 -0.56 7.84e-12 Cognitive performance; TGCT cis rs3733585 0.699 rs13328050 chr4:9951120 G/T cg00071950 chr4:10020882 SLC2A9 -0.54 -6.44 -0.5 2.34e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12477438 0.501 rs1133977 chr2:99741984 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.9 -10.02 -0.67 1.14e-17 Chronic sinus infection; TGCT cis rs739496 0.744 rs10849951 chr12:111910912 G/A cg10833066 chr12:111807467 FAM109A 0.36 5.58 0.45 1.44e-7 Platelet count; TGCT cis rs10779751 0.734 rs2486920 chr1:11125050 T/C cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs1799949 0.965 rs11650132 chr17:41326087 T/G cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs9914988 0.619 rs12451955 chr17:27314224 A/G cg17523868 chr17:27313033 SEZ6 -0.56 -4.76 -0.39 5.23e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs67072384 0.901 rs2886366 chr11:72455207 G/C cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs1865760 0.588 rs9467658 chr6:26010881 T/G cg16482183 chr6:26056742 HIST1H1C 0.57 4.95 0.41 2.32e-6 Height; TGCT cis rs422249 0.547 rs174537 chr11:61552680 G/T cg01500311 chr11:61656094 FADS3 -0.34 -5.72 -0.46 7.53e-8 Trans fatty acid levels; TGCT cis rs6429082 0.702 rs10802797 chr1:235705673 A/G cg26050004 chr1:235667680 B3GALNT2 0.52 4.5 0.37 1.55e-5 Adiposity; TGCT cis rs950169 0.887 rs35986397 chr15:84955107 G/A cg17173187 chr15:85201210 NMB 0.57 5.74 0.46 7.02e-8 Schizophrenia; TGCT cis rs56104184 0.779 rs17206686 chr19:49356317 A/G cg17863274 chr19:49399704 TULP2 -0.4 -4.77 -0.39 5.16e-6 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs12497850 0.931 rs9311434 chr3:48884147 T/C cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs1005277 0.579 rs2983343 chr10:38383332 A/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.2 -0.59 2.5e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7726839 0.540 rs58599998 chr5:596087 A/G cg16624210 chr5:671434 TPPP 0.44 4.85 0.4 3.68e-6 Obesity-related traits; TGCT cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg21672276 chr3:44754072 ZNF502 -0.54 -6.25 -0.49 5.94e-9 Depressive symptoms; TGCT cis rs9814567 1.000 rs6787371 chr3:134254991 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs36051895 0.623 rs7035456 chr9:5261440 G/A cg02405213 chr9:5042618 JAK2 -0.69 -9.16 -0.64 1.34e-15 Pediatric autoimmune diseases; TGCT cis rs3733585 0.673 rs7376505 chr4:9952744 C/A cg00071950 chr4:10020882 SLC2A9 -0.55 -6.58 -0.51 1.21e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2645424 0.762 rs2294139 chr8:11705442 G/T cg12568669 chr8:11666485 FDFT1 -0.34 -4.54 -0.38 1.31e-5 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs4853012 0.775 rs12465641 chr2:74337715 A/G cg19729930 chr2:74357872 NA -0.53 -6.03 -0.48 1.75e-8 Gestational age at birth (maternal effect); TGCT cis rs801193 1.000 rs2707856 chr7:66211010 A/T cg00343986 chr7:65444356 GUSB 0.24 5.26 0.43 6.13e-7 Aortic root size; TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg21672276 chr3:44754072 ZNF502 0.43 4.83 0.4 3.91e-6 Depressive symptoms; TGCT cis rs9443645 0.901 rs6454092 chr6:79701972 G/A cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs1978 chr6:26377573 A/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs910316 1.000 rs2098297 chr14:75619118 G/T cg23033748 chr14:75592666 NEK9 -0.28 -4.64 -0.38 8.62e-6 Height; TGCT cis rs79349575 0.749 rs2546491 chr17:46977916 A/G cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.04e-6 Type 2 diabetes; TGCT cis rs2070433 0.800 rs2073380 chr21:47863757 A/C cg12379764 chr21:47803548 PCNT 0.54 4.67 0.39 7.77e-6 Lymphocyte counts; TGCT cis rs57221529 0.713 rs12521091 chr5:590710 G/T cg16624210 chr5:671434 TPPP 0.42 4.49 0.37 1.64e-5 Lung disease severity in cystic fibrosis; TGCT cis rs9611565 0.765 rs727563 chr22:41867377 C/T cg06481639 chr22:41940642 POLR3H 0.59 5.13 0.42 1.08e-6 Vitiligo; TGCT cis rs2645424 0.639 rs35581201 chr8:11706834 T/C cg16012489 chr8:11489852 NA 0.19 4.68 0.39 7.28e-6 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs10782582 0.609 rs5745394 chr1:76311731 G/A cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs6840360 0.582 rs6813735 chr4:152326990 T/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.35 -0.5 3.68e-9 Intelligence (multi-trait analysis); TGCT cis rs4927850 1.000 rs7627706 chr3:195753353 A/C cg12923728 chr3:195709715 SDHAP1 -0.36 -7.57 -0.56 7.39e-12 Pancreatic cancer; TGCT cis rs3806843 0.750 rs2563285 chr5:140126137 T/C cg19875535 chr5:140030758 IK -0.34 -5.68 -0.45 9.12e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9807989 0.524 rs6543126 chr2:103027104 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs12497850 0.931 rs13316620 chr3:49045355 T/C cg05785598 chr3:49045655 WDR6 0.36 4.8 0.4 4.48e-6 Parkinson's disease; TGCT cis rs10504229 0.683 rs73605816 chr8:58117167 T/C cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs8031584 0.918 rs3817498 chr15:31268781 T/C cg08704250 chr15:31115839 NA -0.35 -4.69 -0.39 6.97e-6 Huntington's disease progression; TGCT cis rs1371867 0.846 rs1660323 chr8:101278724 T/A cg06002616 chr8:101225028 SPAG1 -0.57 -6.77 -0.52 4.48e-10 Atrioventricular conduction; TGCT cis rs9916302 0.706 rs903507 chr17:37726423 A/G cg07936489 chr17:37558343 FBXL20 -0.84 -6.16 -0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs10206020 0.842 rs7609325 chr2:1574718 G/A cg01028140 chr2:1542097 TPO -0.28 -4.51 -0.38 1.47e-5 IgG glycosylation; TGCT cis rs9549367 0.789 rs2287253 chr13:113891075 G/A cg18105134 chr13:113819100 PROZ 0.35 5.58 0.45 1.44e-7 Platelet distribution width; TGCT cis rs35883536 0.565 rs2809813 chr1:101032003 A/C cg06223162 chr1:101003688 GPR88 0.42 8.14 0.59 3.53e-13 Monocyte count; TGCT cis rs9443645 0.901 rs7742034 chr6:79737106 A/G cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs9311474 0.508 rs6786919 chr3:52599789 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT trans rs1814175 0.645 rs28445479 chr11:50047999 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs72945132 0.823 rs12292240 chr11:70152612 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs74233809 0.551 rs3740393 chr10:104636655 C/G cg05855489 chr10:104503620 C10orf26 0.75 5.48 0.44 2.31e-7 Birth weight; TGCT cis rs2243480 1.000 rs6958289 chr7:65657111 T/G cg18252515 chr7:66147081 NA 1.22 7.33 0.55 2.53e-11 Diabetic kidney disease; TGCT cis rs7811142 1.000 rs4463351 chr7:100078226 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs10207060 0.778 rs6543581 chr2:240702308 C/T cg07506560 chr2:240697449 NA -0.58 -7.14 -0.54 6.82e-11 Obesity-related traits; TGCT cis rs6977660 0.714 rs12700075 chr7:19791476 G/T cg07541023 chr7:19748670 TWISTNB 0.85 4.84 0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs2346177 0.542 rs6718875 chr2:46687982 G/T cg26688816 chr2:46740690 ATP6V1E2 -0.42 -4.51 -0.38 1.49e-5 HDL cholesterol; TGCT cis rs7914558 0.966 rs10748839 chr10:104953547 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.85 -0.4 3.57e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4455778 0.538 rs13236051 chr7:49097829 T/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7659604 0.539 rs11098646 chr4:122729301 T/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.31 -0.43 4.82e-7 Type 2 diabetes; TGCT cis rs10464366 0.544 rs12701697 chr7:39182165 C/T cg15212455 chr7:39170539 POU6F2 0.3 6.73 0.52 5.66e-10 IgG glycosylation; TGCT cis rs1245541 0.562 rs3780949 chr10:73886307 C/T cg09661010 chr10:73848153 SPOCK2 -0.37 -4.53 -0.38 1.39e-5 Insulin-like growth factors; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg11235426 chr6:292522 DUSP22 -0.67 -6.82 -0.52 3.53e-10 Menopause (age at onset); TGCT cis rs9443645 0.901 rs9352675 chr6:79612800 G/A cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT trans rs877282 1.000 rs12763443 chr10:771941 G/A cg22713356 chr15:30763199 NA 1.14 10.05 0.67 9.58e-18 Uric acid levels; TGCT cis rs1348850 0.632 rs13008857 chr2:178514468 G/A cg22681709 chr2:178499509 PDE11A -0.51 -6.37 -0.5 3.35e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg06634786 chr22:41940651 POLR3H 0.83 8.01 0.58 7.07e-13 Vitiligo; TGCT cis rs1552244 0.572 rs59132826 chr3:10169725 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.92 5.38 0.44 3.58e-7 Alzheimer's disease; TGCT cis rs2197308 0.740 rs11182251 chr12:37919611 C/T cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs7772486 0.603 rs2223411 chr6:146028767 T/C cg05347473 chr6:146136440 FBXO30 -0.65 -6.11 -0.48 1.17e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs208520 1.000 rs12193077 chr6:66989548 C/T cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs68170813 0.559 rs80212020 chr7:106957596 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs9467711 0.516 rs1165184 chr6:25836257 C/G cg12310025 chr6:25882481 NA -0.71 -4.8 -0.4 4.43e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs11024102 0.962 rs12575487 chr11:17019317 C/T cg15378786 chr11:17036137 PLEKHA7 0.49 4.57 0.38 1.18e-5 Glaucoma (primary angle closure); TGCT cis rs11190604 0.767 rs10883489 chr10:102194532 T/C cg16005271 chr10:102321736 NA 0.46 4.68 0.39 7.39e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs748404 0.660 rs2467738 chr15:43739936 T/A cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.81 0.4 4.37e-6 Lung cancer; TGCT cis rs4478858 0.611 rs10914338 chr1:31733782 T/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.02 -0.41 1.73e-6 Alcohol dependence; TGCT cis rs806215 0.950 rs3757793 chr7:127225780 G/A cg25922125 chr7:127225783 GCC1 -0.61 -6.3 -0.49 4.71e-9 Type 2 diabetes; TGCT cis rs11718455 0.960 rs13081767 chr3:44004468 T/C cg08738300 chr3:44038990 NA 0.86 6.55 0.51 1.4e-9 Coronary artery disease; TGCT cis rs9859260 0.710 rs419068 chr3:195782176 C/T cg22891161 chr3:195456627 MUC20 0.23 4.6 0.38 1.04e-5 Mean corpuscular volume; TGCT cis rs7412746 0.611 rs16827671 chr1:150738759 T/C cg04414720 chr1:150670196 GOLPH3L 0.36 4.44 0.37 1.97e-5 Melanoma; TGCT cis rs6988636 1.000 rs7002332 chr8:124185442 G/C cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs7552404 0.924 rs12136754 chr1:76230232 C/A cg03433033 chr1:76189801 ACADM 0.8 9.43 0.65 3.01e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs896854 0.517 rs1011795 chr8:95951073 G/A cg09323728 chr8:95962352 TP53INP1 -0.43 -4.85 -0.4 3.68e-6 Type 2 diabetes; TGCT cis rs6558530 0.640 rs7844748 chr8:1702343 C/T cg09410841 chr8:1729607 CLN8 -0.72 -6.56 -0.51 1.31e-9 Systolic blood pressure; TGCT cis rs9467711 0.516 rs523383 chr6:25869848 A/G cg03264133 chr6:25882463 NA -0.71 -4.84 -0.4 3.73e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1997103 1.000 rs6951294 chr7:55400835 C/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs35306767 0.855 rs12761180 chr10:872086 C/T cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs908922 1.000 rs1199150 chr1:152455602 T/C cg20991723 chr1:152506922 NA 0.4 5.0 0.41 1.88e-6 Hair morphology; TGCT cis rs360798 0.512 rs2058566 chr2:63179076 C/T cg17519650 chr2:63277830 OTX1 0.55 4.72 0.39 6.23e-6 Coronary artery disease; TGCT cis rs10986311 0.775 rs10818957 chr9:127152585 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.21 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs4820539 0.934 rs3788351 chr22:23469181 T/C cg14186256 chr22:23484241 RTDR1 0.97 12.13 0.74 8.32e-23 Bone mineral density; TGCT trans rs208520 0.690 rs2208442 chr6:66867004 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT trans rs1814175 0.935 rs11040465 chr11:49689323 C/T cg03929089 chr4:120376271 NA -0.62 -7.03 -0.53 1.23e-10 Height; TGCT cis rs6840360 0.571 rs1473305 chr4:152511721 T/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs732765 0.689 rs8019690 chr14:75135142 A/T cg06637938 chr14:75390232 RPS6KL1 -0.57 -4.95 -0.41 2.4e-6 Non-small cell lung cancer; TGCT cis rs3749237 0.595 rs2878298 chr3:49406080 T/C cg03060546 chr3:49711283 APEH 0.77 8.86 0.62 7.06e-15 Resting heart rate; TGCT cis rs539096 0.697 rs11210887 chr1:44076019 G/A cg12908607 chr1:44402522 ARTN -0.41 -4.52 -0.38 1.41e-5 Intelligence (multi-trait analysis); TGCT cis rs11696845 0.626 rs1111032 chr20:43378770 A/G cg09357268 chr20:43379437 KCNK15 0.24 4.53 0.38 1.36e-5 Obesity-related traits; TGCT cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg13770153 chr20:60521292 NA -0.62 -7.94 -0.58 1.02e-12 Body mass index; TGCT cis rs1018836 0.892 rs13267237 chr8:91550820 T/C cg16814680 chr8:91681699 NA -0.78 -8.29 -0.6 1.62e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1577917 1.000 rs12196411 chr6:86779762 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.86e-7 Response to antipsychotic treatment; TGCT cis rs7223966 0.883 rs2955250 chr17:61959740 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.67 5.25 0.43 6.52e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs7914558 1.000 rs7081075 chr10:104929191 C/T cg15744005 chr10:104629667 AS3MT -0.39 -4.75 -0.39 5.53e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6558530 0.730 rs13256424 chr8:1725004 G/A cg09410841 chr8:1729607 CLN8 0.87 10.26 0.68 2.88e-18 Systolic blood pressure; TGCT cis rs2439831 0.850 rs11856795 chr15:44160582 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs2073300 1.000 rs2073300 chr20:23471681 T/G cg09953122 chr20:23471693 CST8 -0.69 -4.54 -0.38 1.3e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT trans rs1814175 0.904 rs1846289 chr11:49620253 G/A cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT trans rs208520 0.837 rs208467 chr6:66914837 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -9.95 -0.67 1.64e-17 Exhaled nitric oxide output; TGCT cis rs4805272 0.512 rs66830923 chr19:29321277 C/T cg04546413 chr19:29218101 NA 0.72 4.97 0.41 2.16e-6 Plasma omega-3 polyunsaturated fatty acid levels (docosahexaenoic acid); TGCT cis rs9341808 0.754 rs9341810 chr6:80974838 G/A cg08355045 chr6:80787529 NA 0.29 4.98 0.41 2.04e-6 Sitting height ratio; TGCT cis rs6952808 0.635 rs6952727 chr7:1947958 A/G cg04267008 chr7:1944627 MAD1L1 -0.37 -4.88 -0.4 3.25e-6 Bipolar disorder and schizophrenia; TGCT cis rs8077889 0.871 rs11079838 chr17:41898971 G/A cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg05785598 chr3:49045655 WDR6 0.36 4.86 0.4 3.41e-6 Menarche (age at onset); TGCT cis rs7760949 0.888 rs1966191 chr6:13911961 A/C cg27413430 chr6:13925136 RNF182 0.6 5.72 0.46 7.69e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs41271951 0.518 rs12145630 chr1:150263832 A/G cg18798344 chr1:149336151 NA 0.56 4.5 0.37 1.52e-5 Blood protein levels; TGCT cis rs782590 0.837 rs782585 chr2:55922930 C/T cg18811423 chr2:55921094 PNPT1 0.73 8.32 0.6 1.37e-13 Metabolic syndrome; TGCT cis rs17102423 0.594 rs1271582 chr14:65564703 T/G cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.65e-9 Obesity-related traits; TGCT trans rs7824557 0.547 rs2409749 chr8:11078949 G/A cg06636001 chr8:8085503 FLJ10661 -0.75 -6.69 -0.51 6.69e-10 Retinal vascular caliber; TGCT cis rs13108904 0.870 rs2279281 chr4:1245277 T/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.78 -0.39 4.85e-6 Obesity-related traits; TGCT cis rs4808199 0.895 rs4808194 chr19:19435680 T/G cg02546618 chr19:19431379 KIAA0892;SF4 0.63 4.56 0.38 1.23e-5 Nonalcoholic fatty liver disease; TGCT cis rs9611565 0.729 rs12165508 chr22:41819960 T/C cg13695892 chr22:41940480 POLR3H 0.86 8.55 0.61 3.95e-14 Vitiligo; TGCT cis rs780096 0.545 rs2280737 chr2:27589810 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.37 4.74 0.39 5.71e-6 Total body bone mineral density; TGCT cis rs1045714 0.895 rs2293405 chr7:2644607 G/T cg17215154 chr7:2644645 IQCE 0.28 4.92 0.4 2.75e-6 Urate levels in lean individuals; TGCT cis rs2629540 0.889 rs4962402 chr10:126459114 T/G cg08799069 chr10:126477246 METTL10 -0.3 -4.5 -0.37 1.54e-5 Cocaine dependence; TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs28386778 0.562 rs721575 chr17:61782920 A/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.81 -8.37 -0.6 1.02e-13 Prudent dietary pattern; TGCT cis rs908922 0.676 rs4240883 chr1:152526260 C/T cg20991723 chr1:152506922 NA 0.44 5.99 0.47 2.14e-8 Hair morphology; TGCT trans rs208520 0.690 rs3843513 chr6:66836797 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT trans rs1814175 0.617 rs6486020 chr11:49769149 T/G cg11707556 chr5:10655725 ANKRD33B -0.46 -11.72 -0.72 8.37e-22 Height; TGCT cis rs864745 0.967 rs849133 chr7:28192280 C/T cg23620719 chr7:28220237 JAZF1 -0.49 -4.57 -0.38 1.15e-5 Crohn's disease;Type 2 diabetes; TGCT cis rs3845702 0.736 rs72962575 chr2:180862133 C/G cg01881094 chr2:180872142 CWC22 1.06 6.66 0.51 8.12e-10 Schizophrenia; TGCT cis rs67072384 0.892 rs7104664 chr11:72444450 C/T cg03713592 chr11:72463424 ARAP1 -0.9 -4.63 -0.38 9.26e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs7178572 1.000 rs8034133 chr15:77763712 C/G cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs5750830 0.649 rs4821895 chr22:39823015 A/G cg11247378 chr22:39784982 NA -0.73 -9.43 -0.65 3.06e-16 Intelligence (multi-trait analysis); TGCT cis rs6671200 0.920 rs7555236 chr1:95631314 G/A cg20701556 chr1:95698924 RWDD3 0.65 5.58 0.45 1.43e-7 Stearic acid (18:0) levels; TGCT trans rs4332037 0.901 rs7791299 chr7:1935598 T/C cg25206134 chr2:45395956 NA 0.95 7.92 0.58 1.16e-12 Bipolar disorder; TGCT cis rs694739 0.536 rs671976 chr11:64046029 G/A cg02228329 chr11:64053129 BAD;GPR137 0.57 5.04 0.41 1.59e-6 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs295140 1.000 rs67190025 chr2:201172086 C/T cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs11955175 1.000 rs11955175 chr5:40626753 C/T cg17351974 chr5:40835760 RPL37 -0.78 -5.02 -0.41 1.78e-6 Bipolar disorder and schizophrenia; TGCT cis rs4733781 0.871 rs12549794 chr8:131214247 T/C cg16277922 chr8:131349729 ASAP1 0.38 5.04 0.41 1.6e-6 Tuberculosis; TGCT cis rs1538970 0.739 rs4660863 chr1:45955868 T/C cg05343316 chr1:45956843 TESK2 0.81 6.64 0.51 8.93e-10 Platelet count; TGCT cis rs7666738 0.830 rs28417577 chr4:99053007 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1334894 1.000 rs72921231 chr6:35589637 T/C cg24281267 chr6:35479648 TULP1 -0.44 -4.73 -0.39 5.95e-6 Coronary artery disease; TGCT cis rs7914558 1.000 rs4917380 chr10:104775335 C/G cg15744005 chr10:104629667 AS3MT -0.4 -4.97 -0.41 2.21e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2334880 0.587 rs8058188 chr16:71675136 G/A cg00732059 chr16:71740210 PHLPP2 0.3 5.29 0.43 5.45e-7 Malaria; TGCT cis rs72627509 0.951 rs72606404 chr4:57841213 G/C cg26694713 chr4:57773883 REST 0.76 6.6 0.51 1.09e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7727544 0.606 rs17622208 chr5:131717050 G/A cg14196790 chr5:131705035 SLC22A5 0.35 4.81 0.4 4.37e-6 Blood metabolite levels; TGCT cis rs8016982 0.657 rs11625861 chr14:81735001 C/T cg01989461 chr14:81687754 GTF2A1 -0.81 -8.48 -0.61 5.58e-14 Schizophrenia; TGCT cis rs4980532 1 rs4980532 chr11:63680719 C/T cg12527260 chr11:63683744 RCOR2 0.37 4.44 0.37 1.96e-5 Pulse pressure; TGCT trans rs208520 1.000 rs208523 chr6:66954195 G/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.88 -8.21 -0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs7772486 0.701 rs697056 chr6:146003897 C/T cg13319975 chr6:146136371 FBXO30 0.52 4.68 0.39 7.31e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.671 rs832531 chr5:56228401 A/G cg24531977 chr5:56204891 C5orf35 -0.68 -7.13 -0.54 7.4e-11 Initial pursuit acceleration; TGCT cis rs754133 0.507 rs10876531 chr12:54443718 A/C cg16264616 chr12:54390824 NA 0.39 5.49 0.44 2.13e-7 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs796364 0.806 rs34381014 chr2:200916403 C/T cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs11671005 0.735 rs11668420 chr19:58937836 G/A cg13877915 chr19:58951672 ZNF132 0.64 5.12 0.42 1.13e-6 Mean platelet volume; TGCT cis rs2841277 0.802 rs2841269 chr14:105386149 C/G cg21017887 chr14:105400489 NA 0.29 4.47 0.37 1.77e-5 Rheumatoid arthritis; TGCT cis rs8070740 0.898 rs9895440 chr17:5325643 C/A cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.88 0.4 3.15e-6 Menopause (age at onset); TGCT trans rs62103177 0.810 rs62103175 chr18:77622467 C/T cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs950169 0.887 rs35986397 chr15:84955107 G/A cg11189052 chr15:85197271 WDR73 0.8 6.1 0.48 1.25e-8 Schizophrenia; TGCT cis rs8017423 0.872 rs7492857 chr14:90684867 T/G cg04374321 chr14:90722782 PSMC1 -0.76 -7.73 -0.57 3.19e-12 Mortality in heart failure; TGCT cis rs3784262 0.647 rs2414529 chr15:58317094 G/T cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.31 -0.49 4.52e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6121246 0.567 rs6060249 chr20:30190944 G/A cg18721089 chr20:30220636 NA -0.63 -6.88 -0.53 2.67e-10 Mean corpuscular hemoglobin; TGCT cis rs8141529 0.732 rs2239815 chr22:29192670 C/T cg02153584 chr22:29168773 CCDC117 -0.56 -4.95 -0.41 2.34e-6 Lymphocyte counts; TGCT cis rs904251 0.965 rs1317563 chr6:37451854 G/T cg25019722 chr6:37503610 NA -0.43 -5.77 -0.46 5.97e-8 Cognitive performance; TGCT cis rs6951245 1.000 rs113146460 chr7:1105164 C/G cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1541995 1.000 rs34524501 chr15:96289064 T/A cg00882281 chr15:96346592 NA 0.28 4.58 0.38 1.11e-5 Photic sneeze reflex; TGCT cis rs17221829 0.965 rs3881252 chr11:89445186 G/A cg02982614 chr11:89391479 FOLH1B -0.29 -5.09 -0.42 1.3e-6 Anxiety in major depressive disorder; TGCT cis rs111803315 1.000 rs112879614 chr14:60001681 A/G cg22995959 chr14:59931024 GPR135 0.66 4.8 0.4 4.39e-6 Schizophrenia; TGCT cis rs713587 0.713 rs1077492 chr2:25286435 C/T cg01884057 chr2:25150051 NA -0.39 -8.01 -0.58 7.24e-13 Body mass index in non-asthmatics; TGCT cis rs28785552 0.765 rs28850924 chr19:53234323 T/G cg10871876 chr19:53194124 ZNF83 0.57 7.92 0.58 1.13e-12 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs3733585 0.699 rs7435196 chr4:9967556 A/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.63e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6987853 0.933 rs2923434 chr8:42422307 A/G cg20539142 chr8:42623718 CHRNA6 -0.21 -5.11 -0.42 1.18e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs11096990 0.574 rs34070258 chr4:39189752 T/C cg20847110 chr4:39482781 LOC401127 0.16 4.52 0.38 1.42e-5 Cognitive function; TGCT cis rs7666738 0.791 rs17549003 chr4:98969132 A/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2050392 0.762 rs306587 chr10:30722908 G/C cg13289132 chr10:30722225 MAP3K8 -0.4 -4.81 -0.4 4.21e-6 Inflammatory bowel disease; TGCT cis rs4566357 0.576 rs10187255 chr2:227913442 T/A cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.9e-7 Coronary artery disease; TGCT cis rs637571 0.780 rs677029 chr11:65683531 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.53 5.41 0.44 3.08e-7 Eosinophil percentage of white cells; TGCT cis rs2228479 0.850 rs11639925 chr16:89908250 C/T cg06558623 chr16:89946397 TCF25 0.55 4.86 0.4 3.55e-6 Skin colour saturation; TGCT cis rs7191439 0.584 rs7193436 chr16:88748736 T/C cg27087555 chr16:88793112 FAM38A -0.47 -4.72 -0.39 6.29e-6 Plateletcrit; TGCT cis rs7666738 0.830 rs4292341 chr4:98959724 C/T cg17366294 chr4:99064904 C4orf37 0.71 6.76 0.52 4.93e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs35883536 0.528 rs1577511 chr1:101030859 G/A cg10298815 chr1:101004474 GPR88 0.25 4.68 0.39 7.46e-6 Monocyte count; TGCT cis rs2050392 0.624 rs303450 chr10:30725337 C/A cg13289132 chr10:30722225 MAP3K8 -0.46 -5.57 -0.45 1.47e-7 Inflammatory bowel disease; TGCT cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg18230493 chr5:56204884 C5orf35 -0.66 -5.65 -0.45 1.05e-7 Initial pursuit acceleration; TGCT cis rs2982552 0.773 rs11155808 chr6:152056050 C/A cg22157087 chr6:152012887 ESR1 0.21 5.17 0.42 8.93e-7 Bone properties (heel); TGCT cis rs8072100 0.744 rs34537623 chr17:45530203 A/G cg08085267 chr17:45401833 C17orf57 -0.46 -5.07 -0.41 1.4e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs523522 0.962 rs10849758 chr12:120971149 C/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs7666738 0.830 rs1426663 chr4:98990092 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9534288 0.783 rs1126366 chr13:46633148 C/G cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs6089584 1.000 rs6089591 chr20:60570548 A/C cg16423285 chr20:60520624 NA -0.55 -5.88 -0.47 3.5e-8 Body mass index; TGCT cis rs10504229 0.683 rs11784908 chr8:58131472 T/C cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT trans rs8073060 0.504 rs225271 chr17:33969836 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs4654899 0.680 rs4654879 chr1:21186378 G/A cg01072550 chr1:21505969 NA 0.55 8.93 0.63 4.85e-15 Superior frontal gyrus grey matter volume; TGCT cis rs7582180 0.739 rs11123824 chr2:100924029 G/A cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs7792525 chr7:99972122 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs7474896 0.583 rs11011341 chr10:37998500 G/A cg13720705 chr10:37990370 NA 0.33 4.91 0.4 2.86e-6 Obesity (extreme); TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg22520471 chr17:61851767 DDX42;CCDC47 -0.54 -5.11 -0.42 1.19e-6 Prudent dietary pattern; TGCT cis rs7267979 0.789 rs6083810 chr20:25329759 T/A cg13486641 chr20:25479848 NINL 0.16 4.57 0.38 1.17e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.802 rs199755 chr6:25990367 G/A cg03517284 chr6:25882590 NA -0.62 -5.73 -0.46 7.06e-8 Intelligence (multi-trait analysis); TGCT cis rs2762353 1.000 rs2762353 chr6:25794431 A/G cg03517284 chr6:25882590 NA -0.52 -5.29 -0.43 5.3e-7 Blood metabolite levels; TGCT cis rs12519773 0.526 rs6897863 chr5:92512481 A/C cg04854328 chr5:92914828 FLJ42709 -0.3 -4.65 -0.39 8.32e-6 Migraine; TGCT cis rs7095607 0.606 rs4746735 chr10:69950502 A/C cg18986048 chr10:69913749 MYPN -0.54 -5.57 -0.45 1.49e-7 Lung function (FVC); TGCT cis rs10927875 0.929 rs4661674 chr1:16296039 A/G cg21385522 chr1:16154831 NA -0.76 -8.31 -0.6 1.44e-13 Dilated cardiomyopathy; TGCT cis rs875971 0.862 rs11773628 chr7:65982631 G/T cg11764359 chr7:65958608 NA -0.58 -5.42 -0.44 2.92e-7 Aortic root size; TGCT cis rs394563 0.559 rs13219868 chr6:149686518 T/G cg03678062 chr6:149772716 ZC3H12D 0.38 4.8 0.4 4.4e-6 Dupuytren's disease; TGCT cis rs1218582 0.772 rs6683557 chr1:154852307 C/G cg09359103 chr1:154839909 KCNN3 -0.67 -12.43 -0.74 1.54e-23 Prostate cancer; TGCT cis rs523522 0.962 rs7136951 chr12:120941927 C/T cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs4654899 0.965 rs7525620 chr1:21458392 G/A cg01072550 chr1:21505969 NA -0.5 -8.07 -0.59 5.13e-13 Superior frontal gyrus grey matter volume; TGCT cis rs72945132 0.882 rs7942613 chr11:70210675 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs35771425 0.572 rs34552796 chr1:211422229 C/T cg26515805 chr1:211431828 RCOR3 -0.46 -4.78 -0.39 4.85e-6 Educational attainment (years of education); TGCT cis rs12971120 0.891 rs11151961 chr18:72177340 C/T cg25817165 chr18:72167213 CNDP2 -0.27 -4.65 -0.39 8.37e-6 Refractive error; TGCT trans rs1005277 0.505 rs7099777 chr10:38183569 A/C cg17830980 chr10:43048298 ZNF37B 0.74 8.59 0.61 3.11e-14 Extrinsic epigenetic age acceleration; TGCT cis rs951366 0.789 rs7536483 chr1:205718858 A/T cg07167872 chr1:205819463 PM20D1 0.58 7.5 0.56 1.09e-11 Menarche (age at onset); TGCT cis rs7432375 0.933 rs55970317 chr3:136353193 T/G cg12473912 chr3:136751656 NA 0.34 4.93 0.41 2.55e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs3806843 0.868 rs2531349 chr5:140120953 G/A cg19875535 chr5:140030758 IK -0.36 -5.9 -0.47 3.18e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9814567 0.806 rs4519744 chr3:134321523 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs736801 0.964 rs17622656 chr5:131820997 A/G cg02551604 chr5:131831745 NA -0.57 -4.71 -0.39 6.65e-6 Breast cancer;Mosquito bite size; TGCT cis rs42648 0.869 rs10266179 chr7:89909982 C/T cg25739043 chr7:89950458 NA -0.67 -6.71 -0.52 6.23e-10 Homocysteine levels; TGCT cis rs9638182 0.614 rs13234157 chr7:72971728 C/A cg14087351 chr7:73037990 MLXIPL -0.65 -4.88 -0.4 3.18e-6 Triglycerides; TGCT cis rs9911578 1.000 rs6503887 chr17:56993320 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs1215050 1.000 rs1215050 chr4:98849826 A/G cg17366294 chr4:99064904 C4orf37 -0.51 -5.08 -0.42 1.34e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7618915 0.547 rs6768697 chr3:52703615 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs16866061 1.000 rs11688397 chr2:225393173 C/T cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs3008870 1.000 rs35365746 chr1:67438900 G/A cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT trans rs2760061 0.819 rs708115 chr1:228198046 C/T cg16006296 chr10:38738647 LOC399744 -0.31 -7.08 -0.54 9.57e-11 Diastolic blood pressure; TGCT cis rs9291683 0.588 rs3756238 chr4:10013202 C/T cg02734326 chr4:10020555 SLC2A9 0.38 4.56 0.38 1.22e-5 Bone mineral density; TGCT cis rs79349575 0.783 rs11079844 chr17:47028334 G/A cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs11118844 0.843 rs4589119 chr1:221915967 G/A cg04222084 chr1:221915650 DUSP10 -0.85 -5.95 -0.47 2.54e-8 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs6138458 0.961 rs11700073 chr20:24975215 C/G cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs849210 0.517 rs2080419 chr2:206208049 T/C cg11793701 chr2:206547163 NRP2 -0.57 -4.54 -0.38 1.31e-5 Tonsillectomy; TGCT cis rs12950390 0.853 rs56387656 chr17:45860189 C/G cg24803719 chr17:45855879 NA -0.49 -5.03 -0.41 1.64e-6 IgG glycosylation; TGCT cis rs12477438 0.765 rs56167745 chr2:99600478 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.79 -7.94 -0.58 1.06e-12 Chronic sinus infection; TGCT cis rs709400 0.633 rs1951391 chr14:103898313 T/C cg12935359 chr14:103987150 CKB -0.35 -5.28 -0.43 5.66e-7 Body mass index; TGCT cis rs9359856 0.510 rs4235839 chr6:90472410 A/G cg13799429 chr6:90582589 CASP8AP2 0.45 4.66 0.39 7.9e-6 Bipolar disorder; TGCT cis rs11190604 1.000 rs2298075 chr10:102247408 C/A cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4273100 0.573 rs4924783 chr17:19253981 A/G cg03910582 chr17:19030146 GRAPL -0.52 -6.78 -0.52 4.27e-10 Schizophrenia; TGCT cis rs6912958 0.535 rs448580 chr6:88040399 A/C cg04972856 chr6:88032051 C6orf162;GJB7 0.39 4.53 0.38 1.36e-5 Monocyte percentage of white cells; TGCT cis rs1018836 0.663 rs3950221 chr8:91478108 G/A cg16814680 chr8:91681699 NA -0.86 -8.78 -0.62 1.09e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7647973 0.925 rs4955439 chr3:49245645 G/T cg05785598 chr3:49045655 WDR6 -0.39 -4.7 -0.39 6.74e-6 Menarche (age at onset); TGCT cis rs7829975 0.533 rs35900578 chr8:8719513 G/A cg08975724 chr8:8085496 FLJ10661 0.58 5.1 0.42 1.23e-6 Mood instability; TGCT cis rs858239 0.896 rs1637193 chr7:23260251 G/T cg05602783 chr7:23145260 KLHL7 -0.55 -4.5 -0.37 1.52e-5 Cerebrospinal fluid biomarker levels; TGCT trans rs9859260 0.744 rs492349 chr3:195784192 G/A cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs514406 0.861 rs562182 chr1:53270010 C/T cg22166914 chr1:53195759 ZYG11B 0.43 7.58 0.56 6.9e-12 Monocyte count; TGCT cis rs769267 0.930 rs6511038 chr19:19607564 A/C cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs2948294 0.588 rs7011221 chr8:8114246 C/T cg15556689 chr8:8085844 FLJ10661 0.78 6.72 0.52 5.79e-10 Red cell distribution width; TGCT cis rs2404602 0.536 rs7163946 chr15:76766049 C/G cg22467129 chr15:76604101 ETFA -0.48 -5.9 -0.47 3.27e-8 Blood metabolite levels; TGCT cis rs1801251 1.000 rs1947105 chr2:233721455 A/G cg25237894 chr2:233734115 C2orf82 0.33 5.94 0.47 2.73e-8 Coronary artery disease; TGCT cis rs4699052 0.662 rs1400363 chr4:104250722 A/C cg16532752 chr4:104119610 CENPE -0.49 -4.79 -0.4 4.66e-6 Testicular germ cell tumor; TGCT cis rs5769765 0.671 rs138832 chr22:50178082 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.32 4.61 0.38 9.79e-6 Schizophrenia; TGCT cis rs734999 0.505 rs60687045 chr1:2539603 G/A cg18854424 chr1:2615690 NA 0.41 4.58 0.38 1.13e-5 Ulcerative colitis; TGCT cis rs3820068 0.581 rs1547033 chr1:15918988 T/C cg05660106 chr1:15850417 CASP9 0.81 8.15 0.59 3.31e-13 Systolic blood pressure; TGCT cis rs854765 0.693 rs35451946 chr17:17764061 C/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.75 -7.78 -0.57 2.42e-12 Total body bone mineral density; TGCT cis rs3784262 0.669 rs4646635 chr15:58252277 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.17 -0.48 8.91e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6087990 0.899 rs1333469 chr20:31361249 C/T cg13636640 chr20:31349939 DNMT3B 1.08 14.21 0.79 8.84e-28 Ulcerative colitis; TGCT cis rs739496 0.527 rs16941703 chr12:112318734 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs916888 0.610 rs142167 chr17:44795234 C/T cg01570182 chr17:44337453 NA -0.79 -7.6 -0.56 6.34e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs910316 1.000 rs12588240 chr14:75612083 C/A cg08847533 chr14:75593920 NEK9 0.96 10.86 0.7 1.05e-19 Height; TGCT cis rs11250098 0.562 rs6987134 chr8:10804906 T/C cg16664915 chr8:10907788 XKR6 -0.29 -4.5 -0.37 1.52e-5 Morning vs. evening chronotype; TGCT cis rs7236492 0.572 rs34712138 chr18:77179833 G/A cg15644404 chr18:77186268 NFATC1 -0.43 -4.5 -0.37 1.57e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs9486719 0.857 rs4265039 chr6:96878929 T/C cg06623918 chr6:96969491 KIAA0776 1.04 11.3 0.71 8.72e-21 Migraine;Coronary artery disease; TGCT cis rs4631830 0.832 rs2337711 chr10:51504604 C/T cg10326726 chr10:51549505 MSMB 0.25 4.75 0.39 5.5e-6 Prostate-specific antigen levels; TGCT cis rs28386778 0.897 rs9912557 chr17:61784963 C/A cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs428668 0.523 rs10060607 chr5:150679304 A/C cg11125805 chr5:150678162 SLC36A3 0.32 7.87 0.58 1.49e-12 Skin aging (microtopography measurement); TGCT cis rs59107033 0.517 rs67946200 chr3:123124824 G/C cg04890266 chr3:123102914 ADCY5 -0.37 -5.59 -0.45 1.39e-7 Lymphocyte counts; TGCT cis rs9372498 0.505 rs4416700 chr6:118975461 G/C cg07617317 chr6:118971624 C6orf204 0.49 5.15 0.42 9.91e-7 Diastolic blood pressure; TGCT cis rs10504229 1.000 rs17816781 chr8:58186161 A/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs1568079 0.516 rs1571424 chr10:125220311 G/A cg14250450 chr10:124578544 NA -0.34 -4.71 -0.39 6.57e-6 Body mass index; TGCT cis rs62103177 1.000 rs62103177 chr18:77624479 G/A cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs3020736 0.500 rs28791586 chr22:42500483 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6893807 1.000 rs13163336 chr5:87943710 C/A cg24804195 chr5:87968844 LOC645323 0.74 5.2 0.42 8.09e-7 Body mass index; TGCT cis rs6951245 0.554 rs76243429 chr7:1152543 C/T cg18402987 chr7:1209562 NA 0.47 4.71 0.39 6.41e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs853679 0.546 rs200953 chr6:27837267 T/C cg08798685 chr6:27730294 NA -0.35 -4.76 -0.39 5.4e-6 Depression; TGCT cis rs1691799 0.899 rs1168357 chr12:66749879 T/C cg16791601 chr12:66731901 HELB -0.29 -6.17 -0.48 8.77e-9 White blood cell count (basophil); TGCT cis rs3960554 0.597 rs3807880 chr7:75864208 T/C cg19105122 chr7:75896889 SRRM3 0.57 4.68 0.39 7.27e-6 Eotaxin levels; TGCT cis rs2594989 0.831 rs7651886 chr3:11572728 A/G cg00170343 chr3:11313890 ATG7 0.64 4.77 0.39 5.18e-6 Circulating chemerin levels; TGCT cis rs4665809 1.000 rs4665821 chr2:26309949 A/C cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs6450176 1.000 rs60492935 chr5:53306240 G/T ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs60843830 1.000 rs2290911 chr2:224919 A/G cg25945732 chr2:264204 ACP1;SH3YL1 0.77 7.62 0.56 5.62e-12 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2032447 0.765 rs6942072 chr6:26014987 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.54 -5.34 -0.43 4.2e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.596 rs7004566 chr8:58115602 G/C cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs7208859 0.673 rs216435 chr17:28922737 G/T cg19761014 chr17:28927070 LRRC37B2 0.56 4.81 0.4 4.32e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12188164 0.965 rs41282625 chr5:475626 C/G cg21144161 chr5:423903 AHRR 0.25 4.64 0.38 8.55e-6 Cystic fibrosis severity; TGCT cis rs6754311 0.731 rs687670 chr2:136740900 T/C cg07169764 chr2:136633963 MCM6 0.62 5.76 0.46 6.23e-8 Mosquito bite size; TGCT cis rs909674 0.865 rs5757683 chr22:39850174 G/A cg02038168 chr22:39784481 NA -0.69 -5.3 -0.43 5.12e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7568458 0.663 rs699664 chr2:85780536 A/G cg02493740 chr2:85810744 VAMP5 0.3 6.33 0.49 4.15e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg12310025 chr6:25882481 NA -0.55 -5.58 -0.45 1.41e-7 Blood metabolite levels; TGCT cis rs739496 0.579 rs10849982 chr12:112335539 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs13217239 0.646 rs4583981 chr6:26992023 G/T cg26531700 chr6:26746687 NA 0.69 6.94 0.53 1.9e-10 Schizophrenia; TGCT cis rs7027203 0.964 rs7854075 chr9:96571211 G/A cg14396892 chr9:96623032 NA 0.26 4.93 0.4 2.62e-6 DNA methylation (variation); TGCT cis rs9443645 0.901 rs2174743 chr6:79591805 G/A cg05283184 chr6:79620031 NA -0.21 -4.68 -0.39 7.33e-6 Intelligence (multi-trait analysis); TGCT cis rs9486715 1.000 rs6899647 chr6:97065661 A/G cg18709589 chr6:96969512 KIAA0776 -0.77 -7.12 -0.54 7.74e-11 Headache; TGCT cis rs4851266 0.966 rs10496345 chr2:100817619 T/G cg07810366 chr2:100720526 AFF3 -0.4 -5.75 -0.46 6.53e-8 Educational attainment; TGCT cis rs713587 0.626 rs62140636 chr2:25233811 T/C cg15423357 chr2:25149977 NA -0.57 -5.77 -0.46 5.89e-8 Body mass index in non-asthmatics; TGCT cis rs9611565 0.659 rs202653 chr22:41840158 C/T cg03806693 chr22:41940476 POLR3H 1.11 12.05 0.73 1.3e-22 Vitiligo; TGCT trans rs4942242 1.000 rs7331003 chr13:44230253 C/T cg19169023 chr15:41853346 TYRO3 -0.33 -6.64 -0.51 9.02e-10 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs10504229 0.679 rs11783963 chr8:58130496 T/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT trans rs6089829 0.962 rs9679865 chr20:61666132 C/G cg23505145 chr19:12996616 KLF1 0.79 8.07 0.59 5.16e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs13082711 0.595 rs6783818 chr3:27361988 C/G cg02860705 chr3:27208620 NA 0.46 6.97 0.53 1.69e-10 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs10744422 1.000 rs2135014 chr12:123333065 C/T cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT trans rs2624839 0.704 rs14321 chr3:50226151 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.79 -7.17 -0.54 5.8200000000000003e-11 Intelligence (multi-trait analysis); TGCT cis rs4720575 0.868 rs7779776 chr7:47092914 C/G cg00036614 chr7:47093842 NA -0.22 -5.41 -0.44 3.06e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs314370 0.573 rs221005 chr7:100401433 A/G cg10426581 chr7:100472382 SRRT 0.72 7.3 0.55 3.02e-11 Resting heart rate; TGCT cis rs951366 0.903 rs708723 chr1:205739266 C/T cg14893161 chr1:205819251 PM20D1 0.4 5.06 0.41 1.49e-6 Menarche (age at onset); TGCT cis rs736408 0.509 rs2590838 chr3:52622086 G/A cg07507251 chr3:52567010 NT5DC2 0.5 7.27 0.55 3.57e-11 Bipolar disorder; TGCT cis rs10779751 1.000 rs4845856 chr1:11274547 T/C cg08854313 chr1:11322531 MTOR 0.91 9.86 0.66 2.71e-17 Body mass index; TGCT cis rs2033711 0.840 rs4801590 chr19:58961813 G/C cg12042659 chr19:58951599 ZNF132 0.51 4.56 0.38 1.23e-5 Uric acid clearance; TGCT cis rs732765 0.734 rs35461658 chr14:75207264 T/C cg06637938 chr14:75390232 RPS6KL1 -0.55 -4.48 -0.37 1.71e-5 Non-small cell lung cancer; TGCT cis rs916888 0.773 rs199534 chr17:44824213 T/G cg17911788 chr17:44343683 NA -0.67 -7.15 -0.54 6.59e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6500602 0.701 rs4785968 chr16:4535307 T/A cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.73 0.39 6.13e-6 Schizophrenia; TGCT cis rs6591182 0.504 rs7130955 chr11:65372580 C/T cg27068330 chr11:65405492 SIPA1 -0.95 -10.69 -0.69 2.62e-19 Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs6496044 0.526 rs4291869 chr15:86054523 G/A cg13263323 chr15:86062960 AKAP13 -0.24 -5.26 -0.43 6.02e-7 Interstitial lung disease; TGCT cis rs9303401 0.527 rs2116450 chr17:56745561 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.53 5.05 0.41 1.55e-6 Cognitive test performance; TGCT cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg24549020 chr5:56110836 MAP3K1 0.67 5.67 0.45 9.57e-8 Initial pursuit acceleration; TGCT cis rs7949030 0.591 rs35156678 chr11:62369881 G/A cg22862634 chr11:62369728 EML3;MTA2 0.7 8.89 0.62 5.98e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2075371 0.611 rs13235296 chr7:134019192 A/G cg11752832 chr7:134001865 SLC35B4 -0.64 -5.3 -0.43 5.22e-7 Mean platelet volume; TGCT cis rs7681440 0.904 rs1442153 chr4:90775719 T/G cg26578617 chr4:90757533 SNCA -0.44 -4.54 -0.38 1.31e-5 Dementia with Lewy bodies; TGCT cis rs2730245 0.550 rs10258339 chr7:158670243 T/C cg24397884 chr7:158709396 WDR60 0.37 4.76 0.39 5.39e-6 Height; TGCT cis rs6951245 0.554 rs75075857 chr7:1140298 C/T cg03188948 chr7:1209495 NA 0.48 5.15 0.42 9.85e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9303401 0.659 rs34818467 chr17:56643109 C/T cg02118635 chr17:56770003 RAD51C;TEX14 -0.58 -5.92 -0.47 2.91e-8 Cognitive test performance; TGCT cis rs10782582 0.609 rs5745331 chr1:76273313 A/G cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs3774830 0.714 rs55816120 chr4:5463350 C/T cg26943120 chr4:5472116 STK32B 0.22 4.82 0.4 4.15e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9300255 0.602 rs2851438 chr12:123643689 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.64 0.45 1.09e-7 Neutrophil percentage of white cells; TGCT cis rs16958440 0.867 rs28587821 chr18:44687906 G/A cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs7100689 0.784 rs1972370 chr10:82127180 A/G cg01528321 chr10:82214614 TSPAN14 0.88 8.48 0.61 5.61e-14 Post bronchodilator FEV1; TGCT cis rs11955175 1.000 rs73080591 chr5:40634687 T/C cg17351974 chr5:40835760 RPL37 0.76 4.75 0.39 5.46e-6 Bipolar disorder and schizophrenia; TGCT cis rs3849570 0.925 rs7641973 chr3:81910489 G/A cg07356753 chr3:81810745 GBE1 -0.74 -6.77 -0.52 4.57e-10 Waist circumference;Body mass index; TGCT cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs8077889 1.000 rs4793035 chr17:41887753 C/T cg26893861 chr17:41843967 DUSP3 1.1 12.5 0.75 1.08e-23 Triglycerides; TGCT cis rs614226 0.935 rs7137953 chr12:120894685 C/T cg01236616 chr12:121019343 POP5 -1.23 -12.24 -0.74 4.57e-23 Type 1 diabetes nephropathy; TGCT cis rs5750830 0.649 rs5750818 chr22:39820885 A/G cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs10089 1.000 rs4836368 chr5:127486330 T/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.77 7.37 0.55 2.14e-11 Ileal carcinoids; TGCT cis rs9972944 0.756 rs7223214 chr17:63761473 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.15 -0.42 9.85e-7 Total body bone mineral density; TGCT cis rs3733585 0.781 rs57250714 chr4:9984529 C/T cg11266682 chr4:10021025 SLC2A9 0.58 7.78 0.57 2.46e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1552244 0.882 rs34706481 chr3:10004123 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.99 6.26 0.49 5.69e-9 Alzheimer's disease; TGCT cis rs916888 0.773 rs199443 chr17:44819565 C/T cg01570182 chr17:44337453 NA 1.07 9.81 0.66 3.57e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs921968 0.679 rs7607369 chr2:219279097 A/G cg02176678 chr2:219576539 TTLL4 0.39 5.69 0.46 8.61e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs6570726 0.764 rs9403733 chr6:145912311 A/C cg13319975 chr6:146136371 FBXO30 -0.54 -4.77 -0.39 5.1e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs6048205 0.649 rs6036144 chr20:22531652 A/G cg03955683 chr17:77216577 HRNBP3 0.9 8.03 0.58 6.57e-13 Fasting blood glucose (BMI interaction);Fasting blood glucose; TGCT cis rs539096 0.830 rs11580074 chr1:44024484 A/G cg12908607 chr1:44402522 ARTN -0.51 -5.28 -0.43 5.57e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.569 rs6002328 chr22:41710034 T/C cg03806693 chr22:41940476 POLR3H -0.75 -7.26 -0.55 3.78e-11 Vitiligo; TGCT cis rs8037137 1.000 rs8037137 chr15:91506637 T/C cg22570213 chr15:91497863 RCCD1 0.5 4.79 0.39 4.74e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs11098499 0.863 rs3775858 chr4:120486028 A/G cg09307838 chr4:120376055 NA 0.74 7.34 0.55 2.49e-11 Corneal astigmatism; TGCT cis rs4665809 0.652 rs11685594 chr2:26402846 A/G cg25036284 chr2:26402008 FAM59B -0.58 -4.61 -0.38 1.01e-5 Gut microbiome composition (summer); TGCT cis rs9611565 0.659 rs56319767 chr22:41933837 G/A cg06481639 chr22:41940642 POLR3H -0.74 -6.74 -0.52 5.38e-10 Vitiligo; TGCT cis rs4455778 0.580 rs4917032 chr7:49111505 T/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT trans rs10802346 0.545 rs1770003 chr1:246408356 A/G cg13514129 chr1:39547527 MACF1 0.96 8.76 0.62 1.21e-14 Fractional exhaled nitric oxide (childhood); TGCT cis rs7267979 1.000 rs2259956 chr20:25282433 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3733585 0.699 rs1122142 chr4:9947548 G/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.42 -0.55 1.62e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs66569888 0.754 rs6719028 chr2:106895212 T/C cg15412446 chr2:106886593 NA 0.46 5.07 0.41 1.42e-6 Facial morphology (factor 23); TGCT cis rs11771526 0.901 rs62457494 chr7:32312299 T/G cg27532318 chr7:32358331 NA 0.57 4.49 0.37 1.61e-5 Body mass index; TGCT cis rs67478160 0.643 rs12880821 chr14:104276049 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.42 -0.5 2.64e-9 Schizophrenia; TGCT trans rs901683 0.702 rs78757497 chr10:46161918 T/C cg18828137 chr12:52968145 KRT74 -0.61 -6.84 -0.52 3.21e-10 Red blood cell traits;Mean corpuscular volume; TGCT cis rs4478858 0.735 rs1566961 chr1:31772450 G/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.03 -0.41 1.67e-6 Alcohol dependence; TGCT cis rs26868 0.742 rs26848 chr16:2263516 A/G cg26873644 chr16:2260806 C16orf79 -0.23 -4.8 -0.4 4.45e-6 Height; TGCT cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg23982607 chr1:1823379 GNB1 -0.56 -8.48 -0.61 5.65e-14 Body mass index; TGCT cis rs7659604 0.539 rs1507995 chr4:122748308 G/A cg19748678 chr4:122722346 EXOSC9 0.89 8.89 0.62 5.91e-15 Type 2 diabetes; TGCT cis rs478304 0.530 rs11568300 chr11:65425167 C/G cg17480646 chr11:65405466 SIPA1 -0.63 -8.35 -0.6 1.14e-13 Acne (severe); TGCT cis rs2658782 0.826 rs2925355 chr11:93090887 T/C cg18152523 chr11:93063302 CCDC67 -0.67 -5.19 -0.42 8.29e-7 Pulmonary function decline; TGCT cis rs36051895 0.623 rs10283473 chr9:5244708 C/A cg02405213 chr9:5042618 JAK2 -0.7 -8.33 -0.6 1.29e-13 Pediatric autoimmune diseases; TGCT cis rs7552404 0.855 rs385897 chr1:76106962 T/C cg03433033 chr1:76189801 ACADM -0.84 -10.07 -0.67 8.46e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13217239 0.646 rs12523820 chr6:27001502 A/G cg02458000 chr6:26745757 NA 0.5 4.61 0.38 1e-5 Schizophrenia; TGCT cis rs6977660 0.714 rs12700075 chr7:19791476 G/T cg05791153 chr7:19748676 TWISTNB 0.88 5.05 0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs12142240 0.698 rs41293285 chr1:46808426 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs11080466 1.000 rs12455026 chr18:10899386 A/T cg02393756 chr18:9912783 VAPA 0.26 4.71 0.39 6.66e-6 Non-small cell lung cancer; TGCT cis rs2455799 0.613 rs2470549 chr3:15737698 T/C cg16303742 chr3:15540471 COLQ -0.26 -4.87 -0.4 3.26e-6 Mean platelet volume; TGCT cis rs3784262 0.631 rs4646625 chr15:58256296 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.11 -0.48 1.19e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs798766 1.000 rs1665366 chr4:1728381 A/G cg05874882 chr4:1763078 NA 0.36 4.87 0.4 3.39e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs10540 1.000 rs61877760 chr11:506596 C/T cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs10782582 0.609 rs1689270 chr1:76390937 A/G cg10523679 chr1:76189770 ACADM -0.54 -4.89 -0.4 3.03e-6 Daytime sleep phenotypes; TGCT cis rs77741769 0.571 rs11065292 chr12:121289155 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.52 0.38 1.43e-5 Mean corpuscular volume; TGCT cis rs763121 0.853 rs4821812 chr22:39075235 G/C cg06022373 chr22:39101656 GTPBP1 0.74 7.31 0.55 2.94e-11 Menopause (age at onset); TGCT cis rs68170813 0.559 rs1989814 chr7:107045076 A/G cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs801193 0.660 rs4610622 chr7:66224497 T/C cg11764359 chr7:65958608 NA 0.56 4.81 0.4 4.32e-6 Aortic root size; TGCT cis rs13256369 0.901 rs12681298 chr8:8566235 A/G cg17143192 chr8:8559678 CLDN23 -0.58 -5.51 -0.44 1.94e-7 Obesity-related traits; TGCT cis rs1670533 0.872 rs10017931 chr4:1060747 G/A cg20887711 chr4:1340912 KIAA1530 0.7 5.54 0.45 1.69e-7 Recombination rate (females); TGCT cis rs992157 0.932 rs10194082 chr2:219188577 C/T cg00012203 chr2:219082015 ARPC2 0.69 6.89 0.53 2.46e-10 Colorectal cancer; TGCT cis rs10823500 0.748 rs12355080 chr10:71963608 G/A cg04118878 chr10:71993077 PPA1 0.59 5.43 0.44 2.84e-7 Blood protein levels; TGCT cis rs7927592 0.731 rs643609 chr11:68241833 A/G cg16797656 chr11:68205561 LRP5 0.26 4.46 0.37 1.79e-5 Total body bone mineral density; TGCT cis rs1670533 1.000 rs6599279 chr4:1058833 G/A cg20887711 chr4:1340912 KIAA1530 0.69 5.48 0.44 2.32e-7 Recombination rate (females); TGCT cis rs2439831 0.867 rs2255042 chr15:43834318 A/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.97 -7.38 -0.55 2.03e-11 Lung cancer in ever smokers; TGCT cis rs2016266 0.855 rs4759086 chr12:53666713 A/G cg16917193 chr12:54089295 NA 0.67 5.1 0.42 1.24e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs6988636 1.000 rs59834873 chr8:124188824 G/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs6582630 0.537 rs12823925 chr12:38409323 C/T cg13010199 chr12:38710504 ALG10B 0.61 4.86 0.4 3.44e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs711245 0.573 rs7570763 chr2:36800589 A/C cg09467607 chr2:36825704 FEZ2 -0.33 -4.82 -0.4 4.15e-6 Height; TGCT cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg13695892 chr22:41940480 POLR3H 0.91 9.11 0.63 1.79e-15 Vitiligo; TGCT trans rs6089829 0.962 rs4809462 chr20:61661560 A/G cg17470723 chr8:74884337 TCEB1 0.71 6.77 0.52 4.48e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs12908161 1.000 rs62019469 chr15:85321220 T/C cg11189052 chr15:85197271 WDR73 0.71 5.85 0.47 4.04e-8 Schizophrenia; TGCT cis rs752010 0.574 rs12130138 chr1:42117792 A/C cg06885757 chr1:42089581 HIVEP3 0.24 4.48 0.37 1.69e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs597539 0.652 rs636049 chr11:68667198 A/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.87 8.55 0.61 3.91e-14 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3845702 0.935 rs6433822 chr2:180840422 G/C cg01881094 chr2:180872142 CWC22 -0.66 -5.84 -0.46 4.29e-8 Schizophrenia; TGCT cis rs796364 0.755 rs203762 chr2:200905136 C/A cg17644776 chr2:200775616 C2orf69 -0.33 -5.0 -0.41 1.91e-6 Schizophrenia; TGCT cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg05368731 chr17:41323189 NBR1 1.16 13.7 0.78 1.41e-26 Menopause (age at onset); TGCT cis rs9296092 0.538 rs62407565 chr6:33535739 A/G cg13560919 chr6:33536144 NA -0.23 -5.04 -0.41 1.58e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs8177253 0.761 rs13079426 chr3:133522334 A/G cg01448562 chr3:133502909 NA -0.38 -7.63 -0.56 5.52e-12 Iron status biomarkers; TGCT cis rs9638182 1.000 rs11974409 chr7:72989390 A/G cg14087351 chr7:73037990 MLXIPL -0.56 -4.73 -0.39 5.97e-6 Triglycerides; TGCT cis rs12579753 0.879 rs11115009 chr12:82165409 G/T cg07988820 chr12:82153109 PPFIA2 0.69 7.77 0.57 2.56e-12 Resting heart rate; TGCT trans rs916888 0.773 rs199448 chr17:44809001 A/G cg22433210 chr17:43662623 NA 0.98 7.07 0.54 1.02e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs3733585 0.699 rs6815001 chr4:9958662 G/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6087990 0.735 rs2424928 chr20:31388636 T/C cg13636640 chr20:31349939 DNMT3B 0.97 12.84 0.76 1.63e-24 Ulcerative colitis; TGCT cis rs6684514 1.000 rs3806409 chr1:156252291 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs11235843 0.636 rs1464908 chr11:73402679 A/C cg18195628 chr11:73498948 MRPL48 -0.64 -4.52 -0.38 1.42e-5 Hand grip strength; TGCT cis rs12474538 0.654 rs12615259 chr2:69509617 T/C cg24886176 chr2:70142158 MXD1 0.71 4.48 0.37 1.67e-5 Breast cancer; TGCT cis rs10114408 0.959 rs3949454 chr9:96644242 G/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9467711 0.606 rs9393708 chr6:26362643 C/T cg10795676 chr6:26370623 BTN3A2 0.45 4.71 0.39 6.5e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs259282 0.646 rs34182086 chr19:33125823 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.64 5.91 0.47 3.14e-8 Schizophrenia; TGCT cis rs11711311 1.000 rs2566968 chr3:113474154 G/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.72 -6.74 -0.52 5.36e-10 IgG glycosylation; TGCT trans rs3822625 0.541 rs10042998 chr5:56205299 A/G cg25190722 chr1:3801660 DFFB 0.54 6.63 0.51 9.27e-10 Breast cancer (early onset); TGCT cis rs6754311 0.731 rs7569057 chr2:136583958 A/C cg07169764 chr2:136633963 MCM6 0.65 6.1 0.48 1.27e-8 Mosquito bite size; TGCT cis rs9910055 0.529 rs615070 chr17:42176591 A/G cg19774624 chr17:42201019 HDAC5 -0.7 -6.8 -0.52 3.88e-10 Total body bone mineral density; TGCT cis rs2486288 0.656 rs8039352 chr15:45551790 A/G cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.54 -0.45 1.75e-7 Glomerular filtration rate; TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.1e-9 Prudent dietary pattern; TGCT cis rs28830936 0.528 rs11630242 chr15:42124643 T/C cg17847044 chr15:42102381 MAPKBP1 -0.18 -4.89 -0.4 3.12e-6 Diastolic blood pressure; TGCT cis rs16866061 0.855 rs11687736 chr2:225405122 A/T cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT trans rs7726839 0.540 rs11739847 chr5:609661 G/A cg25482853 chr8:67687455 SGK3 1.24 10.04 0.67 1.04e-17 Obesity-related traits; TGCT cis rs9926296 0.533 rs10852623 chr16:89865242 T/C cg26513180 chr16:89883248 FANCA 1.03 14.05 0.78 2.1e-27 Vitiligo; TGCT cis rs6951245 0.938 rs78351779 chr7:1097023 G/C cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs492146 0.765 rs316131 chr6:52848149 A/G cg06706454 chr6:52930286 FBXO9 -0.53 -4.95 -0.41 2.37e-6 Epilepsy (remission after treatment); TGCT cis rs806215 1.000 rs2106186 chr7:127241352 G/C cg25922125 chr7:127225783 GCC1 0.59 5.99 0.47 2.15e-8 Type 2 diabetes; TGCT cis rs765787 0.530 rs11854689 chr15:45516052 A/G cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs2288884 0.943 rs11084132 chr19:52514580 C/T cg13540795 chr19:52551618 ZNF432 -0.56 -4.72 -0.39 6.33e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs6141769 0.542 rs6058846 chr20:31324035 A/C cg13636640 chr20:31349939 DNMT3B -0.52 -4.55 -0.38 1.26e-5 Subjective well-being; TGCT cis rs7917772 0.503 rs7078435 chr10:104304766 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.33 0.6 1.3e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg21644426 chr2:191273491 MFSD6 0.62 6.15 0.48 9.57e-9 Pulse pressure; TGCT cis rs1552244 1.000 rs28684871 chr3:10072635 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs9457247 0.534 rs12055488 chr6:167379570 A/G cg23791538 chr6:167370224 RNASET2 0.6 5.72 0.46 7.37e-8 Crohn's disease; TGCT cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg02458000 chr6:26745757 NA 0.51 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs10851411 0.779 rs57502147 chr15:42718749 T/C cg23803468 chr15:43513504 EPB42 0.26 5.04 0.41 1.58e-6 Glucose homeostasis traits; TGCT cis rs9457247 1.000 rs436707 chr6:167388843 T/C cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs4851254 0.550 rs13402289 chr2:100659389 C/T cg22139774 chr2:100720529 AFF3 -0.46 -5.13 -0.42 1.08e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs9787249 0.957 rs7548120 chr1:40204424 A/T cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.54 5.13 0.42 1.11e-6 Electroencephalogram traits; TGCT cis rs7249142 0.549 rs10854012 chr19:19295719 C/T cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.53 5.26 0.43 6e-7 IgG glycosylation; TGCT trans rs797680 0.753 rs11164881 chr1:93658989 C/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.82 -0.52 3.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7647973 1.000 rs9860055 chr3:49506900 C/T cg06212747 chr3:49208901 KLHDC8B -0.57 -4.56 -0.38 1.21e-5 Menarche (age at onset); TGCT trans rs9329221 0.621 rs12156350 chr8:10268516 T/G cg15556689 chr8:8085844 FLJ10661 -0.75 -6.78 -0.52 4.39e-10 Neuroticism; TGCT cis rs597539 0.654 rs655816 chr11:68626405 A/G cg06028808 chr11:68637592 NA 0.54 6.92 0.53 2.19e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1799949 0.965 rs6503726 chr17:41284742 T/C cg23758822 chr17:41437982 NA 0.66 6.44 0.5 2.36e-9 Menopause (age at onset); TGCT cis rs208520 0.690 rs851458 chr6:66813279 T/G cg07460842 chr6:66804631 NA -0.93 -9.66 -0.66 8.29e-17 Exhaled nitric oxide output; TGCT cis rs10540 0.908 rs35608427 chr11:498976 T/C cg03352830 chr11:487213 PTDSS2 0.26 4.46 0.37 1.8e-5 Body mass index; TGCT cis rs4699052 0.625 rs1850321 chr4:104252765 T/C cg16532752 chr4:104119610 CENPE -0.5 -4.92 -0.4 2.71e-6 Testicular germ cell tumor; TGCT cis rs4665809 0.590 rs10197494 chr2:26445550 A/G cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs950169 0.580 rs2271431 chr15:85189464 A/C cg17173187 chr15:85201210 NMB 0.59 6.63 0.51 9.1e-10 Schizophrenia; TGCT cis rs74233809 1.000 rs76752100 chr10:104794086 G/T cg05855489 chr10:104503620 C10orf26 0.76 4.53 0.38 1.36e-5 Birth weight; TGCT cis rs3820928 0.874 rs13393902 chr2:227880554 A/G cg11843606 chr2:227700838 RHBDD1 -0.54 -4.94 -0.41 2.51e-6 Pulmonary function; TGCT cis rs9341808 0.667 rs2476826 chr6:80876064 C/T cg08355045 chr6:80787529 NA 0.3 5.03 0.41 1.65e-6 Sitting height ratio; TGCT cis rs7267979 0.966 rs4815414 chr20:25361701 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs240764 0.658 rs4840147 chr6:101182323 T/C cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.48e-5 Neuroticism; TGCT cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg13770153 chr20:60521292 NA -0.61 -8.66 -0.61 2.06e-14 Obesity-related traits; TGCT cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs7412746 0.634 rs7521592 chr1:150821691 A/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.04 0.41 1.62e-6 Melanoma; TGCT cis rs28785552 0.897 rs34244888 chr19:53242228 T/A cg22067481 chr19:53234126 ZNF611 -0.49 -7.39 -0.55 1.93e-11 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs2243480 1.000 rs13220979 chr7:65363204 G/A cg20637647 chr7:64974828 NA 0.89 4.91 0.4 2.76e-6 Diabetic kidney disease; TGCT cis rs17826219 0.706 rs57698184 chr17:29064918 T/C cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Body mass index; TGCT cis rs1801251 1.000 rs991873 chr2:233711046 A/G cg08000102 chr2:233561755 GIGYF2 -0.63 -6.46 -0.5 2.2e-9 Coronary artery disease; TGCT cis rs2204008 0.626 rs11520260 chr12:38330092 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs2663905 0.611 rs1509560 chr15:81391713 T/G cg09888468 chr15:81410853 NA -0.64 -5.49 -0.44 2.16e-7 QT interval (drug interaction); TGCT cis rs6582630 0.555 rs10880544 chr12:38473464 G/C cg26384229 chr12:38710491 ALG10B 0.83 7.6 0.56 6.18e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs4478858 0.684 rs10798839 chr1:31731758 C/G cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs7588746 0.544 rs2163548 chr2:201226862 C/G cg17644776 chr2:200775616 C2orf69 -0.35 -4.87 -0.4 3.33e-6 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs250677 0.958 rs43147 chr5:148417103 C/G cg23229984 chr5:148520753 ABLIM3 -0.21 -4.92 -0.4 2.64e-6 Breast cancer; TGCT cis rs7267979 1.000 rs3002702 chr20:25268920 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6545883 1.000 rs6742276 chr2:61768745 G/A cg15711740 chr2:61764176 XPO1 -0.57 -5.29 -0.43 5.32e-7 Tuberculosis; TGCT cis rs4563143 0.675 rs56322221 chr19:29270349 A/T cg12667521 chr19:29218732 NA 0.53 5.63 0.45 1.16e-7 Methadone dose in opioid dependence; TGCT cis rs7582180 0.652 rs11675901 chr2:100951189 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.76 0.39 5.35e-6 Intelligence (multi-trait analysis); TGCT cis rs10992471 0.729 rs2181585 chr9:95551830 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.56 -5.25 -0.43 6.46e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs798766 0.859 rs798727 chr4:1685137 C/T cg05874882 chr4:1763078 NA -0.34 -4.68 -0.39 7.52e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs11249608 0.548 rs11951738 chr5:178491228 G/A cg23951258 chr5:178450506 ZNF879 0.45 4.63 0.38 9.16e-6 Pubertal anthropometrics; TGCT cis rs7829975 0.617 rs4841072 chr8:8791253 C/A cg15556689 chr8:8085844 FLJ10661 -0.64 -5.81 -0.46 5.02e-8 Mood instability; TGCT cis rs7847628 0.765 rs7026635 chr9:123550027 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 -0.53 -4.96 -0.41 2.24e-6 Birth weight; TGCT cis rs868036 0.718 rs4776982 chr15:68114974 C/T cg05925327 chr15:68127851 NA 0.51 5.04 0.41 1.63e-6 Restless legs syndrome; TGCT cis rs1990950 0.692 rs6556027 chr5:156860377 G/A cg25387487 chr5:157003181 ADAM19 0.29 4.53 0.38 1.37e-5 Lung function (FEV1/FVC); TGCT cis rs10504229 1.000 rs59797486 chr8:58174435 T/C cg22535103 chr8:58192502 C8orf71 -0.38 -4.88 -0.4 3.25e-6 Developmental language disorder (linguistic errors); TGCT cis rs1552244 0.882 rs61429272 chr3:10037320 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT trans rs11671005 0.504 rs7257669 chr19:59064939 T/C cg22037779 chr5:139682734 PFDN1 -0.85 -6.86 -0.52 2.89e-10 Mean platelet volume; TGCT cis rs9517320 0.534 rs61971163 chr13:99188883 G/A cg20487152 chr13:99095054 FARP1 -0.24 -4.44 -0.37 1.93e-5 Longevity; TGCT cis rs10193935 1.000 rs10171023 chr2:42407093 G/C cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7010267 0.935 rs6469789 chr8:119960661 C/G cg17171407 chr8:119960777 TNFRSF11B 0.33 6.18 0.49 8.29e-9 Total body bone mineral density (age 45-60); TGCT cis rs1577917 0.958 rs12207374 chr6:86656645 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs7582180 0.629 rs11688285 chr2:100948054 A/C cg08017756 chr2:100939284 LONRF2 -0.29 -4.63 -0.38 9.13e-6 Intelligence (multi-trait analysis); TGCT cis rs3849570 0.514 rs4389498 chr3:82015395 G/A cg07356753 chr3:81810745 GBE1 -0.62 -5.41 -0.44 3.17e-7 Waist circumference;Body mass index; TGCT cis rs2692947 0.727 rs749457 chr2:96795944 A/G cg22654517 chr2:96458247 NA 0.22 4.83 0.4 4e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs1799949 0.965 rs6503727 chr17:41312859 C/T cg05368731 chr17:41323189 NBR1 1.02 11.18 0.71 1.73e-20 Menopause (age at onset); TGCT cis rs8008002 1.000 rs8007975 chr14:75865544 G/A cg20011974 chr14:75469661 EIF2B2 -0.5 -4.48 -0.37 1.65e-5 Response to paliperidone in schizophrenia (positive Marder score); TGCT cis rs644799 0.544 rs525087 chr11:95632266 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.49 4.83 0.4 3.9e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7666738 0.830 rs7678567 chr4:99057346 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6933660 0.683 rs6916340 chr6:151779064 T/C cg10883421 chr6:151773342 RMND1;C6orf211 0.8 9.07 0.63 2.27e-15 Menarche (age at onset); TGCT cis rs72781680 1.000 rs72796351 chr2:24158425 T/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs11096990 0.613 rs4974995 chr4:39218123 C/T cg20847110 chr4:39482781 LOC401127 -0.16 -4.49 -0.37 1.64e-5 Cognitive function; TGCT cis rs4654899 0.643 rs2053981 chr1:21227083 G/A cg01072550 chr1:21505969 NA -0.54 -8.87 -0.62 6.73e-15 Superior frontal gyrus grey matter volume; TGCT cis rs1467026 0.563 rs12629928 chr3:12811796 C/T cg05775895 chr3:12838266 CAND2 0.72 7.41 0.55 1.73e-11 P wave duration; TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg21548813 chr6:291882 DUSP22 -0.71 -7.52 -0.56 9.59e-12 Menopause (age at onset); TGCT cis rs6964587 0.967 rs10429103 chr7:91598443 T/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs1552244 1.000 rs7611218 chr3:10063960 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs873946 0.648 rs12767283 chr10:134557094 C/G cg18305652 chr10:134549665 INPP5A 0.35 5.69 0.45 8.83e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6860806 0.507 rs273917 chr5:131659618 A/G cg24060327 chr5:131705240 SLC22A5 -0.74 -7.82 -0.57 1.96e-12 Breast cancer; TGCT cis rs4727027 0.704 rs12537763 chr7:148903984 G/A cg12479418 chr7:148823350 ZNF425;ZNF398 0.52 4.73 0.39 6.1e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs5760092 0.618 rs4461358 chr22:24260106 T/C cg15242686 chr22:24348715 GSTTP1 -0.53 -6.37 -0.5 3.34e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6952808 0.895 rs4513875 chr7:1928159 C/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.68 -0.39 7.46e-6 Bipolar disorder and schizophrenia; TGCT cis rs9650657 0.530 rs6982381 chr8:10952500 A/T cg21775007 chr8:11205619 TDH -0.55 -5.28 -0.43 5.55e-7 Neuroticism; TGCT cis rs10984561 0.881 rs58300957 chr9:122252793 C/T cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs2239815 0.515 rs5762848 chr22:29236308 A/G cg02153584 chr22:29168773 CCDC117 0.67 4.57 0.38 1.17e-5 Esophageal cancer (squamous cell);Esophageal squamous cell carcinoma; TGCT cis rs1865760 0.865 rs6929805 chr6:25950834 T/A cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT cis rs8177253 0.530 rs8177177 chr3:133463195 A/G cg16262614 chr3:133464971 TF 0.36 4.67 0.39 7.69e-6 Iron status biomarkers; TGCT cis rs12477438 0.798 rs896886 chr2:99652713 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.66 5.87 0.47 3.77e-8 Chronic sinus infection; TGCT cis rs7635838 0.587 rs1992910 chr3:11311942 C/T cg00170343 chr3:11313890 ATG7 0.61 5.98 0.47 2.16e-8 HDL cholesterol; TGCT cis rs6951245 0.529 rs76001997 chr7:1152615 C/T cg23708337 chr7:1209742 NA 0.44 4.99 0.41 2e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2735413 0.564 rs6564508 chr16:78116575 T/C cg09132178 chr16:78079569 NA 0.35 4.51 0.38 1.47e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs12478296 1.000 rs55742408 chr2:243041077 G/A cg06360820 chr2:242988706 NA -0.59 -4.52 -0.38 1.45e-5 Obesity-related traits; TGCT cis rs6951245 0.872 rs75398423 chr7:1098414 T/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2224391 0.628 rs2753233 chr6:5250982 T/G cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs35146811 0.538 rs3823642 chr7:99796072 T/C cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs2760061 0.599 rs849903 chr1:228137659 T/C cg02753203 chr1:228287806 NA -0.34 -6.48 -0.5 1.93e-9 Diastolic blood pressure; TGCT trans rs35851103 0.600 rs4841662 chr8:11843758 A/G cg06636001 chr8:8085503 FLJ10661 -0.75 -7.34 -0.55 2.41e-11 Neuroticism; TGCT trans rs2832077 0.527 rs2832116 chr21:30228368 C/A cg14791747 chr16:20752902 THUMPD1 1.09 12.67 0.75 4.09e-24 Cognitive test performance; TGCT cis rs7811142 1.000 rs66632384 chr7:100018904 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs7095607 0.606 rs7084233 chr10:69958343 T/C cg18986048 chr10:69913749 MYPN 0.57 5.92 0.47 2.89e-8 Lung function (FVC); TGCT cis rs858239 0.704 rs466240 chr7:23338774 C/T cg00469287 chr7:23338798 C7orf30 -0.42 -4.49 -0.37 1.6e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs9560113 0.573 rs61955236 chr13:112242861 G/A cg10483660 chr13:112241077 NA 0.36 5.51 0.44 1.97e-7 Menarche (age at onset); TGCT cis rs1568889 1.000 rs34667360 chr11:28055650 T/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.85 9.04 0.63 2.64e-15 Bipolar disorder; TGCT cis rs1018836 0.892 rs10105142 chr8:91547420 C/T cg16814680 chr8:91681699 NA -0.68 -7.82 -0.57 1.97e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7945705 0.935 rs2653567 chr11:8889630 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.46 -5.31 -0.43 4.98e-7 Hemoglobin concentration; TGCT cis rs941873 0.772 rs7086293 chr10:81103247 T/C cg09469691 chr10:81107165 PPIF 0.54 5.4 0.44 3.23e-7 Height; TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg15687855 chr3:44754131 ZNF502 -0.45 -5.36 -0.43 3.94e-7 Depressive symptoms; TGCT cis rs10504229 0.683 rs79284841 chr8:58107611 T/A cg21724239 chr8:58056113 NA 0.48 5.12 0.42 1.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs79349575 0.783 rs11079844 chr17:47028334 G/A cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs6570726 0.764 rs9403731 chr6:145907937 G/A cg05347473 chr6:146136440 FBXO30 0.51 4.74 0.39 5.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11971779 0.878 rs4732378 chr7:139120395 C/T cg07862535 chr7:139043722 LUC7L2 0.78 5.7 0.46 8.32e-8 Diisocyanate-induced asthma; TGCT trans rs797680 0.964 rs1932314 chr1:93638400 G/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.68 -0.51 7.13e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7187223 0.826 rs2317972 chr16:82467476 G/A cg03212183 chr16:81565917 CMIP 0.25 4.49 0.37 1.62e-5 Non-word repetition; TGCT cis rs10791097 0.694 rs2236711 chr11:130739284 G/A cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9911578 1.000 rs9901114 chr17:56575208 G/A cg05425664 chr17:57184151 TRIM37 0.59 5.8 0.46 5.07e-8 Intelligence (multi-trait analysis); TGCT cis rs35160687 0.901 rs6714362 chr2:86476588 A/G cg12542933 chr2:85804724 VAMP8 -0.4 -4.78 -0.39 4.86e-6 Night sleep phenotypes; TGCT cis rs7772486 0.776 rs2265467 chr6:146218339 T/A cg05347473 chr6:146136440 FBXO30 0.53 5.23 0.43 6.96e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10992471 0.729 rs1022844 chr9:95553464 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.56 -5.2 -0.42 8.06e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9473924 0.542 rs9473954 chr6:50928547 G/A cg14470998 chr6:50812995 TFAP2B 1.37 7.34 0.55 2.4e-11 Body mass index; TGCT cis rs2067615 0.524 rs10778504 chr12:107120424 C/T cg15890332 chr12:107067104 RFX4 0.28 5.53 0.44 1.82e-7 Heart rate; TGCT cis rs2839186 0.619 rs55689527 chr21:47622727 A/G cg13732083 chr21:47605072 C21orf56 0.35 4.47 0.37 1.77e-5 Testicular germ cell tumor; TGCT trans rs797680 0.820 rs11164879 chr1:93655522 G/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.82 -0.52 3.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7267979 0.903 rs6050482 chr20:25226327 C/T cg14121845 chr20:25566513 NINL 0.48 5.22 0.42 7.27e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3849570 0.673 rs13068700 chr3:81975817 G/C cg07356753 chr3:81810745 GBE1 -0.73 -6.87 -0.53 2.74e-10 Waist circumference;Body mass index; TGCT cis rs9325144 0.560 rs12424821 chr12:38649951 C/T cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs908922 0.676 rs478926 chr1:152511533 G/T cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs4689388 0.581 rs11727100 chr4:6281458 A/C cg14416269 chr4:6271139 WFS1 0.47 5.6 0.45 1.32e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7772486 0.754 rs9390358 chr6:146145678 C/T cg05347473 chr6:146136440 FBXO30 0.53 4.99 0.41 2.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs422249 0.512 rs1535 chr11:61597972 A/G cg19610905 chr11:61596333 FADS2 -1.06 -11.49 -0.72 2.97e-21 Trans fatty acid levels; TGCT cis rs4478858 0.684 rs7515988 chr1:31731061 C/T cg00250761 chr1:31883323 NA 0.25 4.44 0.37 1.98e-5 Alcohol dependence; TGCT cis rs4733781 0.583 rs1340022 chr8:131334465 T/C cg16277922 chr8:131349729 ASAP1 0.47 7.3 0.55 3e-11 Tuberculosis; TGCT cis rs514406 0.893 rs6588446 chr1:53425260 G/A cg24675658 chr1:53192096 ZYG11B 0.69 7.85 0.58 1.64e-12 Monocyte count; TGCT cis rs7811142 1.000 rs60478351 chr7:100089017 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.69 0.62 1.83e-14 Platelet count; TGCT cis rs3087591 0.960 rs2905797 chr17:29537458 G/C cg24425628 chr17:29625626 OMG;NF1 0.42 6.22 0.49 7.06e-9 Hip circumference; TGCT cis rs3741404 0.584 rs645461 chr11:63893694 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.78 -7.74 -0.57 2.98e-12 Platelet count; TGCT cis rs17376456 0.877 rs10052428 chr5:93476530 T/C cg25358565 chr5:93447407 FAM172A 0.92 8.23 0.59 2.17e-13 Diabetic retinopathy; TGCT cis rs7208859 0.623 rs80355557 chr17:29154421 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.1 0.42 1.26e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17376456 0.825 rs17372725 chr5:93135588 C/A cg21475434 chr5:93447410 FAM172A 0.61 4.82 0.4 4.11e-6 Diabetic retinopathy; TGCT cis rs9457247 0.902 rs366938 chr6:167403538 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs1218582 0.772 rs4845688 chr1:154884142 T/C cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs4319547 0.695 rs10734915 chr12:122873408 A/C cg05707623 chr12:122985044 ZCCHC8 -0.61 -4.74 -0.39 5.7e-6 Body mass index; TGCT cis rs1552244 0.832 rs66597916 chr3:10195407 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 1.1 6.25 0.49 6.06e-9 Alzheimer's disease; TGCT cis rs6835098 0.692 rs6822683 chr4:174063974 G/A cg08422745 chr4:174089978 GALNT7 -0.8 -9.03 -0.63 2.7e-15 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs11190604 0.806 rs76835764 chr10:102193612 C/T cg23241863 chr10:102295624 HIF1AN 0.65 4.89 0.4 3e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28386778 0.765 rs1974435 chr17:61994096 G/A cg01411255 chr17:61851458 DDX42;CCDC47 -0.74 -7.71 -0.57 3.59e-12 Prudent dietary pattern; TGCT cis rs826838 0.967 rs34496261 chr12:39023829 G/A cg13010199 chr12:38710504 ALG10B 0.83 6.91 0.53 2.21e-10 Heart rate; TGCT cis rs7091068 0.721 rs618951 chr10:95404967 A/G cg20715218 chr10:95462985 C10orf4 -0.54 -5.15 -0.42 9.95e-7 Urinary tract infection frequency; TGCT cis rs2180341 0.782 rs6912552 chr6:127722946 C/G cg24812749 chr6:127587940 RNF146 -0.62 -4.92 -0.4 2.7e-6 Breast cancer; TGCT cis rs8103278 1.000 rs9676288 chr19:46292060 G/T cg11657440 chr19:46296263 DMWD -0.59 -5.72 -0.46 7.41e-8 Coronary artery disease; TGCT cis rs12477438 0.834 rs10179043 chr2:99687490 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.47 -0.61 6.04e-14 Chronic sinus infection; TGCT cis rs7178572 0.568 rs1602925 chr15:77685857 T/C cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs2204008 0.837 rs10876019 chr12:37985477 C/T cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs9549260 0.848 rs966968 chr13:41248037 C/T cg21288729 chr13:41239152 FOXO1 -1.01 -10.52 -0.69 7e-19 Red blood cell count; TGCT cis rs7568458 0.870 rs6757263 chr2:85803542 A/G cg02493740 chr2:85810744 VAMP5 -0.27 -4.83 -0.4 3.93e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9611565 0.765 rs28604950 chr22:41785812 A/G cg03806693 chr22:41940476 POLR3H -0.99 -10.42 -0.68 1.22e-18 Vitiligo; TGCT cis rs17681684 0.565 rs62066044 chr17:9762454 G/A cg15743799 chr17:9805578 RCVRN -0.28 -6.0 -0.47 1.99e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs2153535 0.580 rs1932283 chr6:8477661 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs60843830 0.661 rs11674477 chr2:105822 C/G cg25945732 chr2:264204 ACP1;SH3YL1 0.56 4.89 0.4 3.11e-6 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9389248 0.690 rs1028314 chr6:135255710 A/C cg24558204 chr6:135376177 HBS1L -0.47 -4.87 -0.4 3.3e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs6461049 0.765 rs3800908 chr7:2159437 C/T cg04267008 chr7:1944627 MAD1L1 -0.35 -4.7 -0.39 6.89e-6 Schizophrenia; TGCT cis rs1941023 0.503 rs10750936 chr11:60144180 G/A cg08716584 chr11:60157161 MS4A7 -0.34 -4.84 -0.4 3.81e-6 Congenital heart disease (maternal effect); TGCT cis rs6088580 0.634 rs6058070 chr20:33103521 G/C cg06115741 chr20:33292138 TP53INP2 0.53 4.65 0.39 8.41e-6 Glomerular filtration rate (creatinine); TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg10975897 chr6:15504844 JARID2 0.84 5.05 0.41 1.54e-6 Gambling; TGCT cis rs6500602 0.701 rs6500614 chr16:4573938 A/G cg08645402 chr16:4508243 NA 0.2 4.85 0.4 3.55e-6 Schizophrenia; TGCT cis rs240764 0.631 rs9322174 chr6:101204193 G/C cg21058520 chr6:100914733 NA 0.34 4.44 0.37 2e-5 Neuroticism; TGCT cis rs1552244 1.000 rs6807846 chr3:10134491 G/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs1008375 1.000 rs28552744 chr4:17620165 A/G cg18681998 chr4:17616180 MED28 1.01 11.3 0.71 8.54e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1580019 0.922 rs59938271 chr7:32484844 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.9 8.65 0.61 2.27e-14 Cognitive ability; TGCT cis rs13191362 1.000 rs34591938 chr6:163087003 C/G cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.52 0.65 1.89e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9291683 0.597 rs11722989 chr4:10126139 A/G cg00071950 chr4:10020882 SLC2A9 -0.45 -4.94 -0.41 2.49e-6 Bone mineral density; TGCT cis rs713587 0.967 rs713586 chr2:25158008 A/G cg15423357 chr2:25149977 NA 0.63 6.43 0.5 2.52e-9 Body mass index in non-asthmatics; TGCT cis rs11578119 0.898 rs4399219 chr1:170382776 C/T cg09767346 chr1:170501363 GORAB -0.72 -5.72 -0.46 7.52e-8 Male-pattern baldness; TGCT trans rs28735056 1.000 rs3826576 chr18:77633976 G/A cg05926928 chr17:57297772 GDPD1 -0.7 -7.56 -0.56 7.89e-12 Schizophrenia; TGCT cis rs6964587 0.869 rs13237856 chr7:91551788 G/A cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs7178572 0.633 rs12907746 chr15:77843326 A/G cg22256960 chr15:77711686 NA -0.82 -7.51 -0.56 1.03e-11 Type 2 diabetes; TGCT cis rs56104184 0.723 rs116909499 chr19:49407733 C/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs317689 0.690 rs570256 chr12:69662929 A/T cg14784868 chr12:69753453 YEATS4 0.53 4.51 0.38 1.5e-5 Response to diuretic therapy; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg16325326 chr1:53192061 ZYG11B 0.6 6.77 0.52 4.62e-10 Monocyte count; TGCT cis rs7584330 0.868 rs7571898 chr2:238383028 T/C cg16989719 chr2:238392110 NA -0.26 -4.48 -0.37 1.7e-5 Prostate cancer; TGCT cis rs826838 1.000 rs10880963 chr12:38748408 T/C cg26384229 chr12:38710491 ALG10B 1.08 10.82 0.7 1.3e-19 Heart rate; TGCT cis rs801193 1.000 rs4717319 chr7:66242593 A/G cg00343986 chr7:65444356 GUSB 0.23 4.97 0.41 2.14e-6 Aortic root size; TGCT cis rs7659604 0.702 rs61217486 chr4:122693973 T/C cg19748678 chr4:122722346 EXOSC9 0.83 8.84 0.62 8.1e-15 Type 2 diabetes; TGCT cis rs2980439 0.818 rs2948294 chr8:8094961 A/G cg08975724 chr8:8085496 FLJ10661 0.58 5.4 0.44 3.29e-7 Neuroticism; TGCT cis rs2172802 1.000 rs35550109 chr4:62462234 A/G cg04118610 chr4:62707027 LPHN3 0.4 4.65 0.39 8.47e-6 Partial epilepsies; TGCT cis rs28386778 0.897 rs2727327 chr17:61923422 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.02 0.53 1.3e-10 Prudent dietary pattern; TGCT cis rs2354432 0.546 rs11240030 chr1:146882616 G/A cg25205988 chr1:146714368 CHD1L 1.16 7.68 0.57 4.11e-12 Mitochondrial DNA levels; TGCT trans rs7819412 0.511 rs2898290 chr8:11433909 T/C cg15556689 chr8:8085844 FLJ10661 -0.77 -7.2 -0.54 5.08e-11 Triglycerides; TGCT cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg26818010 chr10:134567672 INPP5A -0.38 -5.19 -0.42 8.5e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT trans rs6089829 0.962 rs9680064 chr20:61666168 G/A cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs950169 0.887 rs220333 chr15:85091133 C/T cg12863693 chr15:85201151 NMB 0.4 4.47 0.37 1.73e-5 Schizophrenia; TGCT cis rs6460942 0.915 rs72584550 chr7:12304990 G/A cg06484146 chr7:12443880 VWDE -0.43 -4.63 -0.38 8.94e-6 Coronary artery disease; TGCT cis rs3213545 0.700 rs2260445 chr12:121468863 C/A cg02403541 chr12:121454288 C12orf43 0.7 7.86 0.58 1.63e-12 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs1453308 1.000 rs4663645 chr2:237185631 A/T cg19324714 chr2:237145437 ASB18 0.57 5.08 0.41 1.37e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT trans rs916888 0.531 rs183211 chr17:44788310 G/A cg22433210 chr17:43662623 NA 0.94 7.95 0.58 9.69e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2032447 0.530 rs9356996 chr6:26008487 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 7.09 0.54 8.81e-11 Intelligence (multi-trait analysis); TGCT cis rs4780401 0.527 rs4780402 chr16:11839809 C/T cg01061890 chr16:11836724 TXNDC11 -0.48 -4.48 -0.37 1.65e-5 Rheumatoid arthritis; TGCT cis rs597539 0.652 rs546382 chr11:68704264 C/T cg21862992 chr11:68658383 NA 0.46 6.26 0.49 5.67e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs514406 0.505 rs269286 chr1:53169018 C/T cg16325326 chr1:53192061 ZYG11B -0.82 -10.87 -0.7 9.63e-20 Monocyte count; TGCT cis rs4665809 1.000 rs4665823 chr2:26312723 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs6579837 1.000 rs6579837 chr5:150434894 G/T cg11901248 chr5:149866502 NA -0.59 -4.63 -0.38 8.93e-6 Sjögren's syndrome; TGCT cis rs12950390 0.814 rs4794099 chr17:45838358 T/C cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.6e-6 IgG glycosylation; TGCT cis rs9948 0.786 rs62156234 chr2:97436292 C/G cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs6688613 0.694 rs3820387 chr1:166820284 A/T cg07049167 chr1:166818506 POGK 0.24 5.15 0.42 9.86e-7 Refractive astigmatism; TGCT cis rs7647973 1.000 rs6805609 chr3:49471522 C/G cg06212747 chr3:49208901 KLHDC8B -0.71 -5.41 -0.44 3.07e-7 Menarche (age at onset); TGCT cis rs6490294 0.659 rs11066028 chr12:112245170 A/C cg10833066 chr12:111807467 FAM109A 0.33 5.27 0.43 5.76e-7 Mean platelet volume; TGCT cis rs4665809 1.000 rs3910272 chr2:26287842 T/A cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 0.5 5.42 0.44 2.93e-7 Lymphocyte counts; TGCT cis rs6964587 1.000 rs28735847 chr7:91592755 T/C cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs9926296 0.744 rs164749 chr16:89708224 A/C cg04287289 chr16:89883240 FANCA -0.45 -4.45 -0.37 1.9e-5 Vitiligo; TGCT cis rs7954584 0.635 rs11043242 chr12:122356293 G/C cg21171335 chr12:122356390 WDR66 0.65 7.12 0.54 7.51e-11 Mean corpuscular volume; TGCT cis rs3785574 0.962 rs2955235 chr17:61966950 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.54 0.45 1.71e-7 Height; TGCT trans rs9951602 0.512 rs9946138 chr18:76654608 A/G cg02800362 chr5:177631904 HNRNPAB 1.14 12.55 0.75 7.84e-24 Obesity-related traits; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.04 0.41 1.59e-6 Prudent dietary pattern; TGCT cis rs35306767 0.904 rs35667562 chr10:950630 G/A cg26597838 chr10:835615 NA 0.82 12.45 0.75 1.39e-23 Eosinophil percentage of granulocytes; TGCT cis rs10479542 0.896 rs10078712 chr5:178978805 C/T cg14820908 chr5:178986412 RUFY1 -0.45 -4.5 -0.37 1.54e-5 Lung cancer; TGCT cis rs9788721 0.806 rs4887056 chr15:78734585 A/G cg18825076 chr15:78729989 IREB2 -0.33 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs7267979 0.586 rs1007708 chr20:25190959 C/T cg14121845 chr20:25566513 NINL 0.46 4.85 0.4 3.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.9 7.36 0.55 2.22e-11 Platelet count; TGCT cis rs9682041 0.660 rs13089256 chr3:170113601 G/A cg11886554 chr3:170076028 SKIL 0.62 4.85 0.4 3.59e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7769051 0.711 rs9493436 chr6:133088275 T/C cg22852734 chr6:133119734 C6orf192 1.18 6.54 0.51 1.46e-9 Type 2 diabetes nephropathy; TGCT cis rs3806933 0.500 rs10491423 chr5:110453977 C/A cg04022379 chr5:110408740 TSLP 0.6 6.36 0.5 3.53e-9 Eosinophilic esophagitis; TGCT cis rs6987853 0.901 rs2974344 chr8:42400732 T/G cg20539142 chr8:42623718 CHRNA6 -0.19 -4.58 -0.38 1.11e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs709400 0.526 rs11622473 chr14:103979762 G/A cg26031613 chr14:104095156 KLC1 0.74 6.0 0.47 2.03e-8 Body mass index; TGCT cis rs9902453 0.808 rs1986555 chr17:28014448 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.76e-11 Coffee consumption (cups per day); TGCT cis rs295140 0.507 rs4673814 chr2:201108133 G/A cg23649088 chr2:200775458 C2orf69 -0.32 -5.38 -0.43 3.62e-7 QT interval; TGCT cis rs7772486 0.727 rs6941429 chr6:145952283 G/A cg23711669 chr6:146136114 FBXO30 0.92 10.45 0.68 1.03e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2249625 0.523 rs1969530 chr6:72861276 A/C cg24401219 chr6:72892597 RIMS1 -0.54 -4.7 -0.39 6.92e-6 Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced); TGCT cis rs7178572 0.568 rs4886862 chr15:77652368 T/C cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs10256972 0.721 rs6975972 chr7:1070468 A/G cg03188948 chr7:1209495 NA 0.45 5.76 0.46 6.15e-8 Longevity;Endometriosis; TGCT cis rs709400 0.628 rs6575984 chr14:103876454 A/G cg26031613 chr14:104095156 KLC1 -0.83 -9.19 -0.64 1.17e-15 Body mass index; TGCT cis rs6921919 0.583 rs9461458 chr6:28355875 C/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.32 -0.43 4.76e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9402673 0.517 rs978036 chr6:135342903 C/T cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Reticulocyte count;High light scatter reticulocyte count; TGCT trans rs7618501 0.521 rs3774759 chr3:49939120 G/T cg21659725 chr3:3221576 CRBN 0.68 7.77 0.57 2.53e-12 Intelligence (multi-trait analysis); TGCT cis rs868036 0.681 rs3784718 chr15:68098004 C/T cg05925327 chr15:68127851 NA -0.5 -4.85 -0.4 3.57e-6 Restless legs syndrome; TGCT cis rs9311474 0.508 rs2878628 chr3:52584715 C/T cg07507251 chr3:52567010 NT5DC2 -0.47 -6.64 -0.51 8.85e-10 Electroencephalogram traits; TGCT cis rs3749237 0.595 rs10865955 chr3:49499829 G/A cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs875971 1.000 rs1167411 chr7:65539264 C/G cg18876405 chr7:65276391 NA -0.35 -5.19 -0.42 8.26e-7 Aortic root size; TGCT cis rs7267979 1.000 rs2259926 chr20:25281733 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2762353 0.808 rs1165150 chr6:25842032 C/T cg03517284 chr6:25882590 NA -0.62 -6.51 -0.5 1.7e-9 Blood metabolite levels; TGCT cis rs12927205 0.510 rs7185601 chr16:72035082 A/G cg06353428 chr16:71660113 MARVELD3 0.88 4.85 0.4 3.64e-6 Cholesterol, total;LDL cholesterol; TGCT cis rs1552244 0.938 rs66915020 chr3:10110174 A/G cg00149659 chr3:10157352 C3orf10 0.94 6.02 0.48 1.82e-8 Alzheimer's disease; TGCT cis rs13223928 0.621 rs4722440 chr7:3155901 C/T cg19214707 chr7:3157722 NA 0.46 6.97 0.53 1.7e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs9910055 0.639 rs227583 chr17:42231698 C/G cg19774624 chr17:42201019 HDAC5 -0.87 -10.69 -0.69 2.7e-19 Total body bone mineral density; TGCT cis rs9926296 0.585 rs6500450 chr16:89858024 A/G cg03388025 chr16:89894329 SPIRE2 0.48 8.08 0.59 4.79e-13 Vitiligo; TGCT cis rs1552244 0.872 rs7646073 chr3:10097405 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9653442 0.564 rs4851253 chr2:100762786 T/G cg07810366 chr2:100720526 AFF3 -0.37 -5.49 -0.44 2.16e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7772486 0.902 rs2777480 chr6:146309983 T/A cg23711669 chr6:146136114 FBXO30 0.77 7.93 0.58 1.08e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs79057730 0.599 rs6944167 chr7:826274 G/C cg06242242 chr7:766104 PRKAR1B;HEATR2 0.64 5.28 0.43 5.51e-7 Initial pursuit acceleration; TGCT cis rs2032447 0.670 rs198834 chr6:26114372 G/A cg12310025 chr6:25882481 NA 0.52 4.72 0.39 6.18e-6 Intelligence (multi-trait analysis); TGCT cis rs6951245 0.529 rs10262070 chr7:1141738 C/T cg23708337 chr7:1209742 NA 0.43 4.91 0.4 2.84e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2153535 0.541 rs1414353 chr6:8485642 C/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7267979 1.000 rs6083804 chr20:25317060 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3617 0.591 rs11918800 chr3:52868145 G/A cg11645453 chr3:52864694 ITIH4 -0.29 -5.71 -0.46 7.84e-8 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4819052 0.851 rs875621 chr21:46682295 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.53 0.38 1.35e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2535633 0.631 rs2581819 chr3:53016552 C/A cg05573699 chr3:52720067 GNL3;PBRM1 0.55 5.24 0.43 6.68e-7 Body mass index; TGCT cis rs6684514 1.000 rs2273833 chr1:156233189 C/T cg16558208 chr1:156270281 VHLL 0.48 9.29 0.64 6.47e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9325144 0.624 rs10783330 chr12:39114084 A/G cg10518543 chr12:38710700 ALG10B -0.51 -4.68 -0.39 7.43e-6 Morning vs. evening chronotype; TGCT cis rs2239547 0.657 rs2276817 chr3:52860936 C/T cg10802521 chr3:52805072 NEK4 -0.62 -5.85 -0.47 4.1e-8 Schizophrenia; TGCT cis rs6460942 0.841 rs17444203 chr7:12461864 C/G cg06484146 chr7:12443880 VWDE 0.53 5.59 0.45 1.36e-7 Coronary artery disease; TGCT cis rs9858542 1.000 rs13316695 chr3:49684917 C/G cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs78487399 0.808 rs7567535 chr2:43668261 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1799949 1.000 rs72829113 chr17:41181835 C/T cg10047753 chr17:41438598 NA 0.84 7.61 0.56 5.9e-12 Menopause (age at onset); TGCT cis rs59197085 0.551 rs58518485 chr7:128437731 G/A cg00260937 chr7:128520193 KCP 0.45 4.66 0.39 7.95e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs5769707 0.609 rs2007024 chr22:49988815 C/T cg06623630 chr22:50017776 C22orf34 -0.25 -4.45 -0.37 1.91e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7618915 0.547 rs13065019 chr3:52685244 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs782590 0.818 rs2627782 chr2:55825352 A/G cg03859395 chr2:55845619 SMEK2 0.84 10.09 0.67 7.69e-18 Metabolic syndrome; TGCT cis rs2013441 1.000 rs17759959 chr17:20024095 A/G cg23224458 chr17:20280056 CCDC144C 0.4 4.82 0.4 4.1e-6 Obesity-related traits; TGCT cis rs13217239 0.572 rs9379958 chr6:27066163 A/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.61 -0.38 9.71e-6 Schizophrenia; TGCT cis rs68170813 0.559 rs3801958 chr7:106961139 C/T cg02696742 chr7:106810147 HBP1 -0.71 -5.83 -0.46 4.43e-8 Coronary artery disease; TGCT cis rs7937682 0.921 rs10891280 chr11:111433609 A/T cg09085632 chr11:111637200 PPP2R1B 0.87 7.31 0.55 2.9e-11 Primary sclerosing cholangitis; TGCT cis rs708547 0.735 rs1277280 chr4:57866872 T/G cg25525207 chr4:57843836 C4orf14;POLR2B -0.55 -5.03 -0.41 1.71e-6 Response to bleomycin (chromatid breaks); TGCT cis rs10791097 0.608 rs12363140 chr11:130744268 A/C cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4727027 0.704 rs2888600 chr7:148908562 C/T cg23583168 chr7:148888333 NA -0.85 -10.95 -0.7 6.08e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs9972944 0.902 rs10512503 chr17:63772066 G/A cg07283582 chr17:63770753 CCDC46 0.27 5.27 0.43 5.91e-7 Total body bone mineral density; TGCT cis rs910316 1.000 rs11845639 chr14:75570293 C/T cg23033748 chr14:75592666 NEK9 0.28 4.72 0.39 6.22e-6 Height; TGCT trans rs4332037 0.901 rs7791299 chr7:1935598 T/C cg10840412 chr1:235813424 GNG4 0.89 6.9 0.53 2.37e-10 Bipolar disorder; TGCT cis rs7412746 0.658 rs11581757 chr1:150892244 A/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.5 0.37 1.53e-5 Melanoma; TGCT cis rs12210905 0.688 rs72845028 chr6:27528408 T/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs73198271 0.960 rs73198288 chr8:8613940 G/A ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.79 -0.39 4.72e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs2013441 1.000 rs2080673 chr17:20062395 C/A cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs2463822 0.669 rs72919484 chr11:62043430 T/C cg06239285 chr11:62104954 ASRGL1 -0.87 -5.04 -0.41 1.6e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs60154123 0.505 rs1319435 chr1:210047618 C/T cg22029157 chr1:209979665 IRF6 -0.74 -5.2 -0.42 7.83e-7 Coronary artery disease; TGCT cis rs2290402 0.536 rs4690204 chr4:881195 C/T cg11315544 chr4:1222440 CTBP1 0.26 4.46 0.37 1.84e-5 Type 2 diabetes; TGCT cis rs174601 0.861 rs174580 chr11:61606642 A/G cg20584555 chr11:61717780 BEST1 -0.23 -4.45 -0.37 1.88e-5 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs2303745 0.589 rs10401700 chr19:17397700 A/C cg04248312 chr19:17393744 ANKLE1 -0.32 -5.44 -0.44 2.69e-7 Systemic lupus erythematosus; TGCT cis rs12681287 0.640 rs7007855 chr8:87429491 T/G cg27223183 chr8:87520930 FAM82B 0.89 6.43 0.5 2.54e-9 Caudate activity during reward; TGCT cis rs6089584 0.888 rs2181590 chr20:60622843 T/C cg13770153 chr20:60521292 NA -0.54 -7.12 -0.54 7.73e-11 Body mass index; TGCT cis rs7666738 0.830 rs11941844 chr4:99042722 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs3008870 1.000 rs4620509 chr1:67449941 A/G cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs950169 0.922 rs11633075 chr15:85113972 C/A cg11189052 chr15:85197271 WDR73 0.77 6.44 0.5 2.34e-9 Schizophrenia; TGCT cis rs4727027 0.645 rs12704072 chr7:148904888 G/A cg23583168 chr7:148888333 NA -0.82 -10.48 -0.69 8.54e-19 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs1472147 0.503 rs73238122 chr7:128433977 G/T cg00260937 chr7:128520193 KCP 0.43 4.94 0.41 2.43e-6 Calcium levels; TGCT cis rs10080237 0.564 rs2490232 chr6:80814802 C/T cg08355045 chr6:80787529 NA -0.34 -5.98 -0.47 2.17e-8 Waist circumference adjusted for body mass index;Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals; TGCT cis rs1215050 0.740 rs1084777 chr4:99017542 C/T cg17366294 chr4:99064904 C4orf37 -0.54 -5.86 -0.47 3.98e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11249608 0.636 rs13361077 chr5:178449174 G/C cg01312482 chr5:178451176 ZNF879 -0.58 -5.77 -0.46 5.94e-8 Pubertal anthropometrics; TGCT cis rs7647973 0.961 rs6778080 chr3:49317338 C/T cg07636037 chr3:49044803 WDR6 -0.65 -5.26 -0.43 6.13e-7 Menarche (age at onset); TGCT trans rs7618501 1.000 rs7649348 chr3:49772375 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.962 rs6122350 chr20:61664617 A/G cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs875971 0.830 rs587360 chr7:65522698 C/A cg11764359 chr7:65958608 NA 0.54 4.66 0.39 7.88e-6 Aortic root size; TGCT cis rs17433780 0.964 rs12121223 chr1:89481583 C/T cg09516651 chr1:89888402 LOC400759 0.3 5.26 0.43 6.05e-7 Carotid intima media thickness; TGCT cis rs60843830 1.000 rs60484953 chr2:221560 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.26 0.55 3.8e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs11249608 0.548 rs2047354 chr5:178455247 T/C cg23951258 chr5:178450506 ZNF879 0.45 4.61 0.38 9.7e-6 Pubertal anthropometrics; TGCT cis rs1059312 1.000 rs12814773 chr12:129280786 C/T cg09035930 chr12:129282057 SLC15A4 0.59 11.76 0.73 6.45e-22 Systemic lupus erythematosus; TGCT cis rs9972944 0.756 rs2318869 chr17:63767736 C/G cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs8016982 0.610 rs2371570 chr14:81709686 C/T cg01989461 chr14:81687754 GTF2A1 0.78 7.8 0.57 2.21e-12 Schizophrenia; TGCT cis rs1801251 1.000 rs283486 chr2:233644223 A/G cg25237894 chr2:233734115 C2orf82 0.33 6.05 0.48 1.57e-8 Coronary artery disease; TGCT cis rs8017423 0.904 rs2149647 chr14:90769539 C/T cg04374321 chr14:90722782 PSMC1 -0.73 -6.71 -0.52 6.06e-10 Mortality in heart failure; TGCT cis rs7666738 0.830 rs62321569 chr4:98984250 T/A cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs12908161 0.959 rs34784022 chr15:85231906 T/C cg11189052 chr15:85197271 WDR73 0.75 6.3 0.49 4.8e-9 Schizophrenia; TGCT cis rs1552244 0.572 rs2054478 chr3:10172211 C/T cg00149659 chr3:10157352 C3orf10 1.2 7.56 0.56 7.9e-12 Alzheimer's disease; TGCT cis rs9527 0.830 rs11191440 chr10:104641511 G/A cg15744005 chr10:104629667 AS3MT -0.51 -6.04 -0.48 1.63e-8 Arsenic metabolism; TGCT cis rs2735413 0.564 rs8059851 chr16:78118332 A/G cg09132178 chr16:78079569 NA 0.35 4.51 0.38 1.47e-5 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs6964587 0.869 rs401 chr7:91527945 T/G cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs453301 0.606 rs7462373 chr8:8899318 G/C cg15556689 chr8:8085844 FLJ10661 -0.65 -5.43 -0.44 2.91e-7 Joint mobility (Beighton score); TGCT cis rs1580019 0.961 rs11765387 chr7:32494790 T/C cg06627557 chr7:32535165 LSM5;AVL9 0.79 7.42 0.55 1.63e-11 Cognitive ability; TGCT cis rs2806561 0.704 rs588387 chr1:23523689 A/G cg12483005 chr1:23474871 LUZP1 0.42 5.41 0.44 3.15e-7 Height; TGCT cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg23172400 chr8:95962367 TP53INP1 -0.38 -6.46 -0.5 2.21e-9 Type 2 diabetes; TGCT cis rs7805747 1.000 rs6464165 chr7:151413124 T/C cg17611936 chr7:151411526 PRKAG2 0.54 6.91 0.53 2.29e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs1862618 0.671 rs2591966 chr5:56233688 T/G cg24531977 chr5:56204891 C5orf35 0.64 6.57 0.51 1.28e-9 Initial pursuit acceleration; TGCT cis rs11578119 0.866 rs17350305 chr1:170377200 C/G cg09767346 chr1:170501363 GORAB -0.66 -5.24 -0.43 6.6e-7 Male-pattern baldness; TGCT cis rs11190604 1.000 rs4919472 chr10:102315864 T/A cg23241863 chr10:102295624 HIF1AN 0.68 5.18 0.42 8.89e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2920503 1.000 rs2920503 chr3:12324230 C/T cg23514324 chr3:12329213 PPARG 0.62 5.71 0.46 7.76e-8 LDL cholesterol; TGCT cis rs4566357 1.000 rs3820926 chr2:227926621 G/T cg11843606 chr2:227700838 RHBDD1 -0.5 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs2046867 0.818 rs6786469 chr3:72873809 A/G cg25664220 chr3:72788482 NA -0.55 -6.29 -0.49 5.01e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs651907 0.535 rs35799195 chr3:101521927 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.4 0.68 1.35e-18 Colorectal cancer; TGCT cis rs9399401 0.667 rs11759653 chr6:142720354 G/A cg03128060 chr6:142623767 GPR126 0.37 4.47 0.37 1.77e-5 Chronic obstructive pulmonary disease; TGCT cis rs7000551 0.581 rs2293145 chr8:22262654 A/T cg12081754 chr8:22256438 SLC39A14 0.34 5.1 0.42 1.21e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10876993 0.806 rs1689598 chr12:58050500 G/C cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs4455778 0.580 rs4524741 chr7:49105138 A/C cg26309511 chr7:48887640 NA 0.48 5.96 0.47 2.44e-8 Lung cancer in never smokers; TGCT cis rs6121246 0.567 rs6060247 chr20:30190720 C/G cg21427119 chr20:30132790 HM13 -0.43 -6.28 -0.49 5.3e-9 Mean corpuscular hemoglobin; TGCT cis rs4294134 0.580 rs11760731 chr7:135244179 C/T cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs35306767 0.715 rs12772979 chr10:1034412 C/T cg26597838 chr10:835615 NA 0.63 7.0 0.53 1.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs6570726 0.905 rs430248 chr6:145874104 A/G cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9650657 0.504 rs10093053 chr8:11037187 T/C cg21775007 chr8:11205619 TDH -0.5 -4.61 -0.38 9.88e-6 Neuroticism; TGCT cis rs174479 0.647 rs174454 chr11:61650747 A/G cg01500311 chr11:61656094 FADS3 -0.3 -5.31 -0.43 4.93e-7 Sphingolipid levels; TGCT cis rs1403694 0.695 rs3774291 chr3:186433471 C/T cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs587847 0.737 rs4923745 chr15:37665497 G/C cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs11677370 0.603 rs10174064 chr2:3849806 C/T cg17052675 chr2:3827356 NA -0.42 -7.13 -0.54 7.31e-11 Type 2 diabetes; TGCT cis rs7666738 0.830 rs13119995 chr4:99026790 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7312933 0.558 rs4768411 chr12:42855390 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.56 -5.5 -0.44 2.06e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2742417 1.000 rs2673035 chr3:45753665 C/G cg04837898 chr3:45731254 SACM1L -0.55 -5.82 -0.46 4.69e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs904251 0.861 rs1757171 chr6:37487044 T/C cg25019722 chr6:37503610 NA -0.51 -6.87 -0.53 2.74e-10 Cognitive performance; TGCT cis rs9926296 0.656 rs2376881 chr16:89827011 C/G cg26513180 chr16:89883248 FANCA 0.71 6.99 0.53 1.53e-10 Vitiligo; TGCT cis rs73001065 0.636 rs8182472 chr19:19539891 A/G cg03709012 chr19:19516395 GATAD2A 0.92 5.0 0.41 1.88e-6 LDL cholesterol; TGCT cis rs6901004 0.803 rs2757571 chr6:111511124 T/G cg15721981 chr6:111408429 SLC16A10 -0.53 -4.64 -0.38 8.82e-6 Blood metabolite levels; TGCT cis rs2737273 0.884 rs7873822 chr9:35726821 G/T cg12717594 chr9:36037454 RECK -0.54 -4.52 -0.38 1.43e-5 Platelet distribution width; TGCT trans rs9388451 0.903 rs9388446 chr6:126064920 T/A cg05039488 chr6:79577232 IRAK1BP1 -0.75 -8.32 -0.6 1.33e-13 Brugada syndrome; TGCT cis rs67311347 0.955 rs4973999 chr3:40460383 G/A cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs1018836 0.923 rs4734269 chr8:91635474 G/C cg16814680 chr8:91681699 NA -0.86 -8.92 -0.63 5.07e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs854765 0.547 rs9897761 chr17:17912011 A/T cg09796270 chr17:17721594 SREBF1 0.25 5.03 0.41 1.65e-6 Total body bone mineral density; TGCT cis rs17068510 0.688 rs77547210 chr8:3865814 A/T cg25338036 chr8:3047536 CSMD1 -0.44 -4.59 -0.38 1.05e-5 Cerebrospinal fluid clusterin levels; TGCT cis rs17376456 0.504 rs7702649 chr5:93065149 C/A cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs1538970 0.962 rs3219463 chr1:45806432 C/T cg05343316 chr1:45956843 TESK2 0.63 4.92 0.4 2.64e-6 Platelet count; TGCT cis rs4975709 0.544 rs4975748 chr5:1866025 G/A cg07747251 chr5:1868357 NA 0.41 6.07 0.48 1.47e-8 Cardiovascular disease risk factors; TGCT cis rs10256972 0.706 rs4285396 chr7:1123738 A/G cg03188948 chr7:1209495 NA 0.44 5.79 0.46 5.51e-8 Longevity;Endometriosis; TGCT cis rs2120019 0.938 rs59094290 chr15:75308561 G/T cg17294928 chr15:75287854 SCAMP5 -0.83 -6.36 -0.5 3.45e-9 Blood trace element (Zn levels); TGCT cis rs7819412 0.522 rs10101329 chr8:10990672 C/T cg21775007 chr8:11205619 TDH -0.6 -5.26 -0.43 5.99e-7 Triglycerides; TGCT cis rs9814567 1.000 rs11928499 chr3:134232350 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7582180 0.764 rs10180423 chr2:100919012 C/G cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.89e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs62321564 chr4:98976496 C/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs10876993 0.928 rs10877001 chr12:58083077 T/C cg15848620 chr12:58087721 OS9 0.72 5.94 0.47 2.73e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs6500602 0.626 rs7665 chr16:4562512 A/G cg08645402 chr16:4508243 NA 0.2 4.97 0.41 2.21e-6 Schizophrenia; TGCT cis rs10504229 0.683 rs61364624 chr8:58134339 T/A cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg18876405 chr7:65276391 NA -0.36 -5.71 -0.46 7.96e-8 Aortic root size; TGCT cis rs7267979 1.000 rs6083809 chr20:25329309 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2811893 0.967 rs232869 chr1:59119135 C/A cg26196860 chr1:59745563 NA 0.24 4.44 0.37 1.96e-5 Diabetic retinopathy; TGCT cis rs2188554 0.958 rs10487367 chr7:117081480 G/T cg08576598 chr7:116962626 WNT2 -0.4 -4.92 -0.4 2.65e-6 Esophageal adenocarcinoma; TGCT trans rs62103177 0.733 rs62096747 chr18:77619568 A/G cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs55882075 0.808 rs6867806 chr5:179179585 C/G cg14593053 chr5:179126677 CANX 0.48 5.25 0.43 6.37e-7 Monocyte percentage of white cells; TGCT cis rs7617773 0.780 rs6793239 chr3:48351618 G/T cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs1894292 0.527 rs2071097 chr4:74369298 G/A cg05868023 chr4:75230803 EREG -0.52 -4.64 -0.38 8.72e-6 Prostate cancer; TGCT cis rs2574985 0.530 rs2144862 chr10:52260398 A/G cg12753529 chr10:51525504 NA -0.23 -4.59 -0.38 1.06e-5 Subjective well-being; TGCT cis rs473651 0.935 rs559579 chr2:239339501 G/C cg08773314 chr2:239334832 ASB1 0.45 6.39 0.5 3.05e-9 Multiple system atrophy; TGCT cis rs2688608 0.592 rs7076585 chr10:75503692 T/C cg04320760 chr10:75533139 FUT11 -0.4 -6.06 -0.48 1.49e-8 Inflammatory bowel disease; TGCT cis rs4808199 0.895 rs4808194 chr19:19435680 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.33 0.43 4.49e-7 Nonalcoholic fatty liver disease; TGCT cis rs11673344 0.523 rs2562594 chr19:37514685 G/A cg08039142 chr19:36980659 ZNF566 0.5 4.72 0.39 6.26e-6 Obesity-related traits; TGCT cis rs9467773 0.526 rs3734536 chr6:26365346 C/G cg05738196 chr6:26577821 NA -0.61 -6.45 -0.5 2.25e-9 Intelligence (multi-trait analysis); TGCT cis rs1568657 1.000 rs1568657 chr15:83726179 A/G cg12240358 chr15:83619523 HOMER2 -0.27 -4.56 -0.38 1.19e-5 Kawasaki disease; TGCT cis rs3820928 1.000 rs7592387 chr2:227777095 A/G cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs425277 0.606 rs2257684 chr1:2077872 A/G cg03732007 chr1:2071316 PRKCZ 0.28 6.63 0.51 9.05e-10 Height; TGCT cis rs3091242 0.933 rs34933589 chr1:25788198 T/C cg09222892 chr1:25734099 RHCE 0.42 6.83 0.52 3.33e-10 Erythrocyte sedimentation rate; TGCT cis rs763121 0.853 rs2413547 chr22:39107338 A/G cg06022373 chr22:39101656 GTPBP1 0.74 7.07 0.54 9.75e-11 Menopause (age at onset); TGCT cis rs42648 0.935 rs42627 chr7:89961876 C/T cg25739043 chr7:89950458 NA -0.71 -7.0 -0.53 1.46e-10 Homocysteine levels; TGCT cis rs9916302 0.851 rs7225096 chr17:37664443 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs3617 0.539 rs11130331 chr3:52956918 G/A cg10802521 chr3:52805072 NEK4 0.57 6.56 0.51 1.34e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg25767906 chr1:53392781 SCP2 0.49 5.52 0.44 1.87e-7 Monocyte count; TGCT cis rs1801251 0.963 rs35395584 chr2:233573698 G/C cg25237894 chr2:233734115 C2orf82 0.32 5.78 0.46 5.59e-8 Coronary artery disease; TGCT cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11122272 0.735 rs2808601 chr1:231536571 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.67 -6.18 -0.49 8.48e-9 Hemoglobin concentration; TGCT cis rs16910800 0.731 rs59333536 chr11:23191649 G/A cg20040320 chr11:23191996 NA -0.51 -4.47 -0.37 1.71e-5 Cancer; TGCT cis rs250677 1.000 rs36069 chr5:148417253 G/C cg23229984 chr5:148520753 ABLIM3 0.2 4.88 0.4 3.13e-6 Breast cancer; TGCT cis rs2760061 0.598 rs632832 chr1:228121838 G/T cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg13393036 chr8:95962371 TP53INP1 -0.58 -7.98 -0.58 8.59e-13 Type 2 diabetes; TGCT cis rs2153535 0.580 rs4365970 chr6:8453813 C/T cg23788917 chr6:8435910 SLC35B3 -0.57 -5.17 -0.42 9.27e-7 Motion sickness; TGCT cis rs2455799 0.613 rs7642876 chr3:15883094 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.8 -0.4 4.53e-6 Mean platelet volume; TGCT cis rs11718455 0.767 rs4682924 chr3:43992760 G/A cg08738300 chr3:44038990 NA 0.75 5.71 0.46 7.9e-8 Coronary artery disease; TGCT cis rs7666738 0.830 rs2903150 chr4:99027184 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6690583 0.623 rs1371141 chr1:85455372 C/A cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs4888262 0.508 rs4462623 chr16:74692426 C/T cg01733217 chr16:74700730 RFWD3 0.73 7.27 0.55 3.62e-11 Testicular germ cell tumor; TGCT cis rs4780355 0.918 rs243318 chr16:11358018 G/A cg00044050 chr16:11439710 C16orf75 0.54 4.77 0.39 5.01e-6 Crohn's disease and psoriasis; TGCT cis rs1538970 0.962 rs9429160 chr1:45827968 G/T cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.580 rs4960421 chr6:8459292 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs13191362 1.000 rs73008453 chr6:163013384 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs62244186 0.659 rs12108134 chr3:44543030 A/G cg02073558 chr3:44770973 ZNF501 -0.62 -5.88 -0.47 3.6e-8 Depressive symptoms; TGCT cis rs12220238 0.722 rs6480742 chr10:76398466 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.63 4.89 0.4 3.02e-6 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs13242816 1.000 rs73206052 chr7:116117056 G/T cg02799643 chr7:116139180 CAV2 -0.46 -4.65 -0.39 8.23e-6 P wave duration; TGCT cis rs10504229 0.953 rs59034808 chr8:58185337 T/C cg21724239 chr8:58056113 NA 0.33 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs910316 1.000 rs28626045 chr14:75589195 G/C cg11812906 chr14:75593930 NEK9 0.74 7.43 0.55 1.56e-11 Height; TGCT cis rs9372498 0.536 rs62422220 chr6:118923731 G/A cg21191810 chr6:118973309 C6orf204 -0.39 -5.13 -0.42 1.07e-6 Diastolic blood pressure; TGCT cis rs35146811 0.735 rs1727138 chr7:99815247 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs6964587 0.967 rs7783414 chr7:91785957 C/T cg22709100 chr7:91322751 NA 0.28 4.5 0.37 1.54e-5 Breast cancer; TGCT trans rs7698623 0.717 rs1982624 chr4:88790847 A/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs1048238 0.506 rs848212 chr1:16263452 A/G cg21385522 chr1:16154831 NA -0.61 -6.78 -0.52 4.39e-10 Systolic blood pressure; TGCT cis rs7208859 0.573 rs73267872 chr17:29067207 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3749237 0.964 rs2352967 chr3:49871641 C/T cg03060546 chr3:49711283 APEH 0.7 7.25 0.55 4.01e-11 Resting heart rate; TGCT cis rs3087591 0.960 rs9898664 chr17:29567152 T/C cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.43 -0.56 1.53e-11 Hip circumference; TGCT cis rs12478296 0.786 rs6721704 chr2:242994923 A/G cg06360820 chr2:242988706 NA -0.63 -5.43 -0.44 2.86e-7 Obesity-related traits; TGCT cis rs17001868 0.568 rs9611329 chr22:40792038 G/T cg07138101 chr22:40742427 ADSL 0.73 5.6 0.45 1.34e-7 Mammographic density (dense area); TGCT cis rs2243480 1.000 rs3885839 chr7:65290403 G/T cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs6665290 0.904 rs10495273 chr1:227183359 T/G cg10327440 chr1:227177885 CDC42BPA -0.99 -20.27 -0.88 3.54e-41 Myeloid white cell count; TGCT cis rs2070433 0.752 rs60290737 chr21:47837630 C/A cg04277056 chr21:48021941 S100B 0.31 4.48 0.37 1.67e-5 Lymphocyte counts; TGCT cis rs3754214 0.823 rs496203 chr1:150270025 A/G cg09579323 chr1:150459698 TARS2 -0.5 -4.52 -0.38 1.43e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs739496 0.947 rs6490162 chr12:111941120 T/C cg10833066 chr12:111807467 FAM109A 0.37 5.38 0.44 3.53e-7 Platelet count; TGCT cis rs3008870 1.000 rs4620509 chr1:67449941 A/G cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs4665809 0.680 rs3955310 chr2:26290828 T/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs644799 1.000 rs544119 chr11:95538624 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2346177 0.519 rs13003074 chr2:46671420 A/T cg26688816 chr2:46740690 ATP6V1E2 0.44 4.77 0.39 5.08e-6 HDL cholesterol; TGCT cis rs7666738 0.830 rs10007872 chr4:99001904 T/C cg17366294 chr4:99064904 C4orf37 0.68 6.96 0.53 1.75e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3785574 0.962 rs62077483 chr17:61806380 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.59 5.3 0.43 5.06e-7 Height; TGCT cis rs950169 0.881 rs4842852 chr15:84941961 A/G cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs2820315 0.838 rs2819347 chr1:201884288 C/G cg12730843 chr1:201915899 LMOD1 -0.27 -4.9 -0.4 2.94e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2274273 0.623 rs1187881 chr14:55489197 G/A cg01923255 chr14:55878535 KIAA0831 -0.58 -4.94 -0.41 2.51e-6 Protein biomarker; TGCT cis rs981844 0.813 rs72731678 chr4:154671476 T/C cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs7147624 0.572 rs72714491 chr14:66024580 T/A cg03016385 chr14:66212404 NA 0.61 7.04 0.53 1.16e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT trans rs853356 1.000 rs853385 chr6:14182741 G/A cg14262035 chr17:42019790 PPY 0.51 6.72 0.52 5.86e-10 Height; TGCT cis rs2463822 1.000 rs2246920 chr11:62104937 T/G cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs854765 0.547 rs2955378 chr17:17930253 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.1 0.59 4.3e-13 Total body bone mineral density; TGCT cis rs13008689 0.875 rs12616139 chr2:8522651 C/T cg26785157 chr2:7987059 NA 0.21 4.85 0.4 3.7e-6 Longevity; TGCT cis rs2688608 0.592 rs10762560 chr10:75495405 T/G cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs7617773 0.780 rs9846818 chr3:48375685 C/T cg11946769 chr3:48343235 NME6 0.74 6.81 0.52 3.67e-10 Coronary artery disease; TGCT cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg03188948 chr7:1209495 NA 0.44 5.76 0.46 6.32e-8 Longevity;Endometriosis; TGCT cis rs4919694 1.000 rs12257941 chr10:104833161 C/T cg04362960 chr10:104952993 NT5C2 1.07 7.2 0.54 5.11e-11 Arsenic metabolism; TGCT cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg03517284 chr6:25882590 NA 0.89 9.12 0.63 1.72e-15 Blood metabolite levels; TGCT cis rs2013441 0.965 rs1544421 chr17:20114217 T/C cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT trans rs9951602 0.541 rs7243702 chr18:76645637 G/A cg02800362 chr5:177631904 HNRNPAB 1.14 13.02 0.76 6.04e-25 Obesity-related traits; TGCT cis rs922182 0.633 rs12592702 chr15:64271882 C/T cg02919090 chr15:64263738 DAPK2 -0.3 -5.37 -0.43 3.82e-7 Blood protein levels; TGCT cis rs4654899 0.865 rs72975078 chr1:21476196 A/G cg01072550 chr1:21505969 NA -0.47 -6.92 -0.53 2.16e-10 Superior frontal gyrus grey matter volume; TGCT cis rs57221529 0.713 rs56328416 chr5:591138 G/A cg09021430 chr5:549028 NA -0.38 -5.12 -0.42 1.14e-6 Lung disease severity in cystic fibrosis; TGCT cis rs986417 0.892 rs78026410 chr14:60801142 G/A cg27398547 chr14:60952738 C14orf39 -1.55 -6.83 -0.52 3.44e-10 Gut microbiota (bacterial taxa); TGCT cis rs6831352 0.918 rs13138294 chr4:100062675 T/G cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs2075371 1.000 rs1862051 chr7:133981021 G/A cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT cis rs1862618 0.853 rs1423620 chr5:56100996 G/T cg24549020 chr5:56110836 MAP3K1 0.67 5.67 0.45 9.58e-8 Initial pursuit acceleration; TGCT cis rs2730245 1.000 rs2527199 chr7:158737113 G/A cg24397884 chr7:158709396 WDR60 -0.4 -5.3 -0.43 5.05e-7 Height; TGCT cis rs4499344 0.657 rs7250123 chr19:33054463 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.72 -6.04 -0.48 1.67e-8 Mean platelet volume; TGCT cis rs617219 0.726 rs7717669 chr5:78452983 A/C cg05890484 chr5:78407552 BHMT 0.37 5.03 0.41 1.7e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs368755101 1 rs368755101 chr2:100762215 AG/A cg22139774 chr2:100720529 AFF3 -0.36 -5.47 -0.44 2.36e-7 Plateletcrit;Red blood cell count; TGCT cis rs1348850 0.914 rs6710575 chr2:178377311 C/T cg22681709 chr2:178499509 PDE11A -0.35 -4.55 -0.38 1.27e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs10791097 0.642 rs7107568 chr11:130779668 T/C cg12179176 chr11:130786555 SNX19 0.85 10.3 0.68 2.3e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3806933 0.522 rs13186912 chr5:110456704 A/T cg04022379 chr5:110408740 TSLP -0.59 -6.16 -0.48 9.28e-9 Eosinophilic esophagitis; TGCT cis rs1862618 0.853 rs9283717 chr5:56078659 G/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.93 -0.47 2.85e-8 Initial pursuit acceleration; TGCT cis rs8050907 0.744 rs78538387 chr16:4523167 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs8014204 0.544 rs2286913 chr14:75386576 G/A cg06637938 chr14:75390232 RPS6KL1 0.93 9.89 0.66 2.35e-17 Caffeine consumption; TGCT cis rs2797160 0.684 rs1832937 chr6:125985934 A/G cg10911889 chr6:126070802 HEY2 -0.51 -4.62 -0.38 9.32e-6 Endometrial cancer; TGCT cis rs9399135 0.967 rs9373122 chr6:135373534 G/A cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs4862750 0.914 rs9998558 chr4:187874691 A/G cg22105103 chr4:187893119 NA 0.32 4.54 0.38 1.31e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2295359 0.892 rs11209004 chr1:67613932 G/A cg03340356 chr1:67600835 NA 0.39 4.65 0.39 8.22e-6 Psoriasis; TGCT cis rs12045440 0.525 rs1472565 chr1:19755030 T/C cg24875000 chr1:19041556 PAX7 0.25 5.6 0.45 1.29e-7 Thyroid volume; TGCT cis rs9611565 0.649 rs202645 chr22:41798520 A/G cg06634786 chr22:41940651 POLR3H 0.89 8.45 0.6 6.78e-14 Vitiligo; TGCT cis rs9611565 0.694 rs9611591 chr22:41830212 G/A cg03806693 chr22:41940476 POLR3H 1.03 11.3 0.71 8.46e-21 Vitiligo; TGCT cis rs4972806 0.775 rs2857534 chr2:177035676 G/T cg14324370 chr2:177042789 NA 0.71 6.56 0.51 1.33e-9 IgG glycosylation; TGCT cis rs6866344 0.570 rs1071882 chr5:178136040 C/T cg10224037 chr5:178157518 ZNF354A 0.97 9.36 0.64 4.38e-16 Neutrophil percentage of white cells; TGCT cis rs7584330 0.554 rs13405619 chr2:238445661 C/T cg08992911 chr2:238395768 MLPH 0.64 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs9303401 0.659 rs34382037 chr17:56643550 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs13256369 0.851 rs13256611 chr8:8564341 G/A cg18904891 chr8:8559673 CLDN23 0.59 5.46 0.44 2.54e-7 Obesity-related traits; TGCT cis rs8177253 0.634 rs6798547 chr3:133448499 G/A cg01448562 chr3:133502909 NA -0.26 -5.06 -0.41 1.49e-6 Iron status biomarkers; TGCT cis rs9486715 0.929 rs2025044 chr6:97067028 A/G cg18709589 chr6:96969512 KIAA0776 -0.79 -7.18 -0.54 5.76e-11 Headache; TGCT cis rs6988636 0.534 rs4489325 chr8:124105254 G/A cg27053337 chr8:124217698 FAM83A 0.54 4.68 0.39 7.34e-6 Urinary uromodulin levels; TGCT cis rs78545713 1.000 rs16891484 chr6:26242930 G/A cg12260798 chr6:26240519 HIST1H4F -0.51 -4.68 -0.39 7.29e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs62283056 0.512 rs4568307 chr4:6284965 A/G cg14416269 chr4:6271139 WFS1 0.41 5.13 0.42 1.1e-6 Cisplatin-induced ototoxicity; TGCT cis rs7917772 0.582 rs10786695 chr10:104368756 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1153858 1.000 rs56806728 chr15:45637814 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs4700695 0.925 rs6449799 chr5:65394476 A/G cg21114390 chr5:65439923 SFRS12 -0.57 -4.49 -0.37 1.59e-5 Facial morphology (factor 19); TGCT cis rs6940638 0.956 rs13207365 chr6:27030980 T/C cg26531700 chr6:26746687 NA -0.6 -4.63 -0.38 9.25e-6 Intelligence (multi-trait analysis); TGCT cis rs13082711 1.000 rs13082711 chr3:27537909 T/C cg02860705 chr3:27208620 NA 0.33 4.56 0.38 1.19e-5 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs2729354 1.000 rs2649662 chr11:57352562 G/T cg24343310 chr11:57249947 NA -0.28 -4.71 -0.39 6.66e-6 Blood protein levels; TGCT cis rs308403 0.509 rs1849431 chr4:123674762 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.82 11.78 0.73 5.72e-22 Blood protein levels; TGCT cis rs4665809 0.590 rs3792007 chr2:26497541 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs1322512 0.760 rs2695252 chr6:152926834 C/T cg03415253 chr6:152958462 SYNE1 -0.55 -5.2 -0.42 8.12e-7 Tonometry; TGCT cis rs36051895 0.623 rs6476957 chr9:5261324 A/G cg02405213 chr9:5042618 JAK2 -0.7 -9.4 -0.65 3.55e-16 Pediatric autoimmune diseases; TGCT cis rs9467773 0.595 rs2172007 chr6:26639777 A/C cg02458000 chr6:26745757 NA 0.65 6.34 0.49 3.92e-9 Intelligence (multi-trait analysis); TGCT cis rs6964587 1.000 rs12531366 chr7:91683849 C/G cg17063962 chr7:91808500 NA 0.89 9.93 0.67 1.84e-17 Breast cancer; TGCT cis rs1865760 0.566 rs9366634 chr6:26072396 C/G cg17042849 chr6:26104293 HIST1H4C -0.63 -5.48 -0.44 2.31e-7 Height; TGCT cis rs2710642 0.927 rs1468748 chr2:63204611 C/T cg17519650 chr2:63277830 OTX1 0.68 6.27 0.49 5.41e-9 LDL cholesterol levels;LDL cholesterol; TGCT cis rs950776 0.752 rs7182583 chr15:78899210 G/C cg06917634 chr15:78832804 PSMA4 0.65 5.26 0.43 6.03e-7 Sudden cardiac arrest; TGCT cis rs4819852 0.958 rs2240716 chr22:19969696 C/T cg07821417 chr22:19972146 ARVCF 0.21 5.37 0.43 3.81e-7 Pulse pressure; TGCT cis rs9503598 0.778 rs10155771 chr6:3465930 G/A cg00476032 chr6:3446245 SLC22A23 0.17 4.87 0.4 3.35e-6 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); TGCT cis rs1784581 0.894 rs1790000 chr6:162388707 A/G cg17173639 chr6:162384350 PARK2 0.49 9.49 0.65 2.15e-16 Itch intensity from mosquito bite; TGCT cis rs6558530 0.666 rs4242539 chr8:1694236 A/G cg09410841 chr8:1729607 CLN8 0.66 5.85 0.46 4.12e-8 Systolic blood pressure; TGCT cis rs2033711 0.870 rs7408188 chr19:58939389 T/G cg13877915 chr19:58951672 ZNF132 0.89 11.16 0.71 1.92e-20 Uric acid clearance; TGCT cis rs9527 0.590 rs10883830 chr10:104851285 G/A cg15744005 chr10:104629667 AS3MT -0.42 -4.84 -0.4 3.82e-6 Arsenic metabolism; TGCT cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg03188948 chr7:1209495 NA 0.45 5.86 0.47 3.93e-8 Longevity;Endometriosis; TGCT cis rs59482735 1 rs59482735 chr9:123643426 T/TAA cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 4.77 0.39 5.05e-6 Prostate-specific antigen levels; TGCT trans rs10953454 1.000 rs34508498 chr7:104480657 C/T cg04208666 chr6:19734707 NA -0.57 -6.89 -0.53 2.52e-10 Obesity; TGCT cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs5769765 1.000 rs5769760 chr22:50259696 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.4 -6.01 -0.47 1.96e-8 Schizophrenia; TGCT cis rs7439150 0.954 rs72679197 chr4:155475159 G/A cg22130008 chr4:155548532 NA -0.43 -5.38 -0.44 3.5e-7 Fibrinogen levels; TGCT cis rs854765 0.663 rs1052299 chr17:17750419 A/G cg09796270 chr17:17721594 SREBF1 -0.3 -5.85 -0.46 4.18e-8 Total body bone mineral density; TGCT cis rs6095298 0.595 rs6095320 chr20:47446595 A/G cg12307787 chr20:48099359 KCNB1 0.44 4.67 0.39 7.75e-6 Intelligence (multi-trait analysis); TGCT cis rs2688608 0.592 rs10762563 chr10:75524802 C/A cg15838173 chr10:75533400 FUT11 -0.3 -4.94 -0.41 2.5e-6 Inflammatory bowel disease; TGCT cis rs6879260 1.000 rs7706951 chr5:179733407 C/T cg23248424 chr5:179741104 GFPT2 -0.38 -7.07 -0.54 9.78e-11 Height; TGCT cis rs10949834 0.540 rs810552 chr7:73489298 A/G cg07137043 chr7:73588983 EIF4H 0.51 4.86 0.4 3.45e-6 Verbal memory performance (residualized delayed recall change); TGCT cis rs7523050 0.643 rs35520362 chr1:109419841 C/T cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs9467773 0.587 rs10946812 chr6:26344975 G/C cg05738196 chr6:26577821 NA -0.62 -6.55 -0.51 1.38e-9 Intelligence (multi-trait analysis); TGCT cis rs916888 0.821 rs199525 chr17:44847834 T/G cg16228356 chr17:43848958 NA -0.26 -4.62 -0.38 9.47e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2535633 0.631 rs6799185 chr3:53101580 C/T cg11645453 chr3:52864694 ITIH4 0.28 5.07 0.41 1.41e-6 Body mass index; TGCT cis rs13126513 0.519 rs7659550 chr4:100554402 G/T cg05468953 chr4:100565104 NA 0.42 5.68 0.45 9.27e-8 Metabolite levels (MHPG); TGCT cis rs1843834 0.574 rs6436499 chr2:225456551 A/T cg12698349 chr2:225449008 CUL3 0.76 6.39 0.5 3.11e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs1153858 1.000 rs12437887 chr15:45669094 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs11785400 0.793 rs4430071 chr8:143737680 T/C cg24634471 chr8:143751801 JRK 0.55 5.51 0.44 1.99e-7 Schizophrenia; TGCT cis rs9926296 0.605 rs6500449 chr16:89856393 T/C cg26513180 chr16:89883248 FANCA 1.07 14.96 0.8 1.48e-29 Vitiligo; TGCT trans rs2624839 0.630 rs2624841 chr3:50198415 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.81 7.51 0.56 1.02e-11 Intelligence (multi-trait analysis); TGCT cis rs921968 0.643 rs4674320 chr2:219510768 A/G cg02176678 chr2:219576539 TTLL4 0.38 5.47 0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs727563 0.594 rs132807 chr22:42071584 T/C cg03806693 chr22:41940476 POLR3H 1.08 11.79 0.73 5.53e-22 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11105298 0.891 rs11105287 chr12:89829470 C/T cg00757033 chr12:89920650 WDR51B 0.31 4.92 0.4 2.72e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs1451375 0.794 rs11238134 chr7:50542927 A/C cg18232548 chr7:50535776 DDC -0.34 -5.16 -0.42 9.39e-7 Malaria; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg18538332 chr22:24372958 LOC391322 -1.02 -13.19 -0.76 2.24e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9926296 0.546 rs9935541 chr16:89905925 G/C cg08627397 chr16:89984028 MC1R -0.34 -5.48 -0.44 2.25e-7 Vitiligo; TGCT cis rs2721195 0.967 rs10108150 chr8:145687475 A/G cg17328964 chr8:145687451 CYHR1 0.51 8.05 0.59 5.62e-13 Age at first birth; TGCT cis rs763121 0.853 rs6001214 chr22:39149155 C/T cg06022373 chr22:39101656 GTPBP1 0.78 7.26 0.55 3.69e-11 Menopause (age at onset); TGCT cis rs1215050 0.776 rs1627946 chr4:98844416 G/A cg17366294 chr4:99064904 C4orf37 -0.57 -6.13 -0.48 1.08e-8 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs9985766 1.000 rs28397206 chr4:151022898 A/G cg02993991 chr19:4064177 ZBTB7A 0.57 6.7 0.52 6.59e-10 Coronary artery disease;Myocardial infarction; TGCT cis rs7945705 0.875 rs2568065 chr11:8889648 C/T cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -5.09 -0.42 1.28e-6 Hemoglobin concentration; TGCT cis rs9486719 1.000 rs4839837 chr6:96908706 G/A cg18709589 chr6:96969512 KIAA0776 0.66 5.35 0.43 4.12e-7 Migraine;Coronary artery disease; TGCT cis rs8072100 0.811 rs1912483 chr17:45443494 A/G cg08085267 chr17:45401833 C17orf57 -0.49 -5.59 -0.45 1.4e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2153535 0.601 rs1928183 chr6:8530018 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs739401 0.611 rs2239900 chr11:3030992 C/T cg25174290 chr11:3078921 CARS 0.47 4.73 0.39 6.07e-6 Longevity; TGCT cis rs2439831 0.850 rs9944216 chr15:44160773 C/G cg02155558 chr15:43621948 ADAL;LCMT2 -0.94 -6.36 -0.5 3.57e-9 Lung cancer in ever smokers; TGCT cis rs7772486 0.686 rs702314 chr6:146003510 G/A cg23711669 chr6:146136114 FBXO30 -0.85 -9.2 -0.64 1.08e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg04234412 chr22:24373322 LOC391322 -0.92 -8.21 -0.59 2.49e-13 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs453301 0.658 rs6986044 chr8:8874786 G/C cg06636001 chr8:8085503 FLJ10661 -0.66 -5.44 -0.44 2.69e-7 Joint mobility (Beighton score); TGCT cis rs6951245 1.000 rs78896566 chr7:1080182 C/G cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs41271951 0.512 rs12070256 chr1:151070090 C/T cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs921968 0.541 rs664514 chr2:219329819 A/G cg02176678 chr2:219576539 TTLL4 0.47 6.72 0.52 5.75e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs739496 0.793 rs655107 chr12:111996557 T/C cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs4434138 0.664 rs62255364 chr3:52701502 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.93 0.47 2.8e-8 Intelligence (multi-trait analysis); TGCT cis rs7523050 0.643 rs12752417 chr1:109400639 A/C cg08274380 chr1:109419600 GPSM2 -1.27 -6.37 -0.5 3.32e-9 Fat distribution (HIV); TGCT cis rs597539 0.652 rs622082 chr11:68703959 A/G cg21862992 chr11:68658383 NA 0.46 6.26 0.49 5.67e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs56104184 0.775 rs73061694 chr19:49399978 T/C cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs6912958 0.631 rs9450704 chr6:88182704 G/C cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs1801251 1.000 rs4517962 chr2:233578337 T/C cg25237894 chr2:233734115 C2orf82 0.31 5.51 0.44 1.96e-7 Coronary artery disease; TGCT cis rs17711722 0.701 rs55773927 chr7:65337902 T/C cg00343986 chr7:65444356 GUSB 0.26 6.11 0.48 1.18e-8 Calcium levels; TGCT cis rs17331151 0.573 rs77223362 chr3:52865125 G/A cg11137980 chr3:52469226 SEMA3G 0.29 5.14 0.42 1.04e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs12368653 0.641 rs12826708 chr12:58058373 G/A cg12615879 chr12:58013172 SLC26A10 0.47 5.46 0.44 2.49e-7 Multiple sclerosis; TGCT cis rs3824867 0.879 rs4752837 chr11:47465955 G/A cg20307385 chr11:47447363 PSMC3 0.7 6.03 0.48 1.71e-8 Mean corpuscular hemoglobin; TGCT cis rs4851266 1.000 rs12991254 chr2:100817933 T/C cg22139774 chr2:100720529 AFF3 -0.38 -5.6 -0.45 1.33e-7 Educational attainment; TGCT cis rs8014204 1.000 rs4553560 chr14:75334199 T/C cg06637938 chr14:75390232 RPS6KL1 -0.77 -7.49 -0.56 1.14e-11 Caffeine consumption; TGCT cis rs9682041 0.597 rs62295834 chr3:170075701 G/A cg07589077 chr3:170072950 NA 0.28 4.85 0.4 3.55e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs4295623 0.559 rs4841600 chr8:11688148 T/C cg21775007 chr8:11205619 TDH 0.57 5.01 0.41 1.84e-6 Morning vs. evening chronotype; TGCT cis rs910316 1.000 rs175492 chr14:75545220 A/C cg23033748 chr14:75592666 NEK9 0.28 4.9 0.4 2.96e-6 Height; TGCT cis rs9916302 0.706 rs8075737 chr17:37727316 C/T cg15445000 chr17:37608096 MED1 -0.35 -4.84 -0.4 3.8e-6 Glomerular filtration rate (creatinine); TGCT cis rs9611565 0.694 rs202656 chr22:41842203 T/A cg17554472 chr22:41940697 POLR3H 0.48 4.95 0.41 2.39e-6 Vitiligo; TGCT cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg04267008 chr7:1944627 MAD1L1 -0.41 -5.4 -0.44 3.34e-7 Bipolar disorder and schizophrenia; TGCT cis rs889312 0.500 rs702691 chr5:56114526 T/G cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs77861329 1.000 rs17051977 chr3:52182944 A/G cg08692210 chr3:52188851 WDR51A 0.83 4.64 0.38 8.71e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs72615157 0.716 rs75779608 chr7:99768957 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.68 5.24 0.43 6.71e-7 Lung function (FEV1/FVC); TGCT cis rs9486719 0.895 rs3798294 chr6:97049587 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs6835098 0.887 rs12644699 chr4:174142874 A/G cg08422745 chr4:174089978 GALNT7 0.88 10.07 0.67 8.46e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs6088590 1.000 rs12626122 chr20:33425800 A/G cg08999081 chr20:33150536 PIGU 0.26 4.45 0.37 1.87e-5 Coronary artery disease; TGCT cis rs4285028 0.948 rs2877560 chr3:121699238 C/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs10170846 0.800 rs10194743 chr2:223518151 A/G cg25565276 chr2:223520875 FARSB 0.57 4.72 0.39 6.18e-6 Schizophrenia (inflammation and infection response interaction); TGCT cis rs9325144 0.555 rs2387843 chr12:38711203 T/C cg26384229 chr12:38710491 ALG10B 0.68 6.28 0.49 5.18e-9 Morning vs. evening chronotype; TGCT cis rs7523273 1.000 rs1142469 chr1:207965427 G/A cg22525895 chr1:207977042 MIR29B2 -0.48 -8.57 -0.61 3.53e-14 Schizophrenia; TGCT cis rs2230307 0.536 rs2784173 chr1:100639752 A/G cg24955406 chr1:100503596 HIAT1 -0.76 -5.21 -0.42 7.5e-7 Carotid intima media thickness; TGCT cis rs3820928 1.000 rs11686072 chr2:227777493 A/T cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs28386778 1.000 rs2665849 chr17:61953670 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.33 0.43 4.5e-7 Prudent dietary pattern; TGCT trans rs7613875 0.580 rs3774745 chr3:50204745 C/T cg21665057 chr3:196295764 WDR53;FBXO45 -0.79 -8.22 -0.59 2.36e-13 Body mass index; TGCT cis rs1129187 0.935 rs4987173 chr6:42931224 G/A cg05552183 chr6:42928497 GNMT 0.52 4.55 0.38 1.25e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4822044 0.560 rs7284839 chr22:42010902 C/T cg03806693 chr22:41940476 POLR3H 1.07 11.4 0.72 4.95e-21 Cannabis dependence symptom count; TGCT cis rs8017423 1.000 rs4904644 chr14:90665689 A/G cg04374321 chr14:90722782 PSMC1 -0.77 -7.89 -0.58 1.34e-12 Mortality in heart failure; TGCT cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg02458000 chr6:26745757 NA 0.71 7.06 0.54 1.07e-10 Intelligence (multi-trait analysis); TGCT cis rs57221529 0.709 rs72703090 chr5:598314 C/T cg20362242 chr5:692897 TPPP 0.53 4.56 0.38 1.22e-5 Lung disease severity in cystic fibrosis; TGCT cis rs11690935 0.885 rs6750058 chr2:172786909 G/T cg13550731 chr2:172543902 DYNC1I2 -0.92 -8.29 -0.6 1.5700000000000001e-13 Schizophrenia; TGCT cis rs6459788 0.720 rs11974772 chr7:157250645 G/A cg03453431 chr7:157225567 NA -0.4 -5.97 -0.47 2.35e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs9308731 0.644 rs1837366 chr2:111874629 C/T cg04202892 chr2:111875749 ACOXL 0.54 6.22 0.49 6.96e-9 Chronic lymphocytic leukemia; TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg05215272 chr17:6899095 ALOX12 -0.5 -6.13 -0.48 1.07e-8 Tonsillectomy; TGCT cis rs9393777 0.764 rs35565446 chr6:27145341 C/T cg16898833 chr6:26189333 HIST1H4D 1.3 5.86 0.47 3.92e-8 Intelligence (multi-trait analysis); TGCT cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1008375 0.932 rs11934968 chr4:17667766 A/G cg16339924 chr4:17578868 LAP3 0.56 4.53 0.38 1.37e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.29 -4.49 -0.37 1.64e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9902453 0.817 rs880749 chr17:28059970 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -7.27 -0.55 3.59e-11 Coffee consumption (cups per day); TGCT cis rs4925386 1.000 rs2151512 chr20:60913495 T/C cg06026331 chr20:60912101 LAMA5 -0.29 -5.37 -0.43 3.71e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs8177253 1.000 rs1525892 chr3:133484712 C/T cg16414030 chr3:133502952 NA -0.61 -9.68 -0.66 7.39e-17 Iron status biomarkers; TGCT cis rs8013055 0.846 rs10151805 chr14:105974781 T/C cg25008857 chr14:105974488 NA 0.27 4.65 0.39 8.35e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs13082711 0.522 rs578501 chr3:27344963 A/G cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT trans rs1814175 0.817 rs28525029 chr11:50045815 A/G cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs56235845 0.694 rs6876677 chr5:176755342 T/C cg17509989 chr5:176798049 RGS14 0.54 7.47 0.56 1.25e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs7829975 0.755 rs3789849 chr8:8687054 G/C cg15556689 chr8:8085844 FLJ10661 0.67 5.97 0.47 2.33e-8 Mood instability; TGCT cis rs9911578 0.835 rs9788975 chr17:56460800 G/A cg05425664 chr17:57184151 TRIM37 0.57 5.19 0.42 8.24e-7 Intelligence (multi-trait analysis); TGCT cis rs910316 0.737 rs175043 chr14:75471803 G/A cg08847533 chr14:75593920 NEK9 -0.84 -8.92 -0.63 5.19e-15 Height; TGCT cis rs11190604 1.000 rs7088827 chr10:102303865 C/G cg16342193 chr10:102329863 NA -0.4 -4.89 -0.4 3.08e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg05552183 chr6:42928497 GNMT 0.52 4.57 0.38 1.17e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg17971929 chr21:40555470 PSMG1 0.97 9.73 0.66 5.86e-17 Cognitive function; TGCT cis rs9916302 0.808 rs12943928 chr17:37611330 G/A cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs7552167 0.925 rs4489498 chr1:24512055 A/G cg01960748 chr1:24522592 NA 0.44 5.01 0.41 1.83e-6 Psoriasis vulgaris; TGCT cis rs4665809 0.652 rs6728090 chr2:26524726 C/T cg22920501 chr2:26401640 FAM59B -0.8 -6.27 -0.49 5.4e-9 Gut microbiome composition (summer); TGCT cis rs4722166 0.597 rs2069845 chr7:22770149 G/A cg13104385 chr7:22767384 IL6 0.23 4.91 0.4 2.79e-6 Lung cancer; TGCT cis rs4629710 0.592 rs11759793 chr6:131546384 G/A cg12606694 chr6:131520996 AKAP7 0.39 4.63 0.38 9.14e-6 Multiple myeloma (IgH translocation); TGCT cis rs4563143 0.675 rs73029050 chr19:29276554 G/T cg04546413 chr19:29218101 NA 0.86 6.96 0.53 1.7e-10 Methadone dose in opioid dependence; TGCT cis rs9325144 0.555 rs4882358 chr12:38726640 A/G cg26384229 chr12:38710491 ALG10B 0.65 6.06 0.48 1.55e-8 Morning vs. evening chronotype; TGCT cis rs9611565 0.649 rs139553 chr22:42187199 A/G cg06481639 chr22:41940642 POLR3H 0.57 4.82 0.4 4.18e-6 Vitiligo; TGCT cis rs7119 0.931 rs11630540 chr15:77833625 G/A cg27398640 chr15:77910606 LINGO1 -0.25 -4.73 -0.39 5.96e-6 Type 2 diabetes; TGCT cis rs1059312 0.966 rs12368452 chr12:129277164 C/A cg09035930 chr12:129282057 SLC15A4 0.6 11.86 0.73 3.65e-22 Systemic lupus erythematosus; TGCT cis rs7666738 0.830 rs28522896 chr4:99008243 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3020736 0.500 rs6002604 chr22:42493081 A/T cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.645 rs56670121 chr8:58138872 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs6722750 0.933 rs12999721 chr2:64407710 C/T cg22352474 chr2:64371530 PELI1 0.53 4.8 0.4 4.49e-6 Neuroticism; TGCT cis rs6088590 1.000 rs28542147 chr20:33376323 G/A cg24642439 chr20:33292090 TP53INP2 0.69 6.13 0.48 1.09e-8 Coronary artery disease; TGCT cis rs12681287 0.640 rs13269259 chr8:87470453 G/A cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs10782582 0.609 rs11588643 chr1:76255613 A/G cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs9611565 0.879 rs5758307 chr22:41750219 A/G cg03806693 chr22:41940476 POLR3H -1.02 -11.0 -0.7 4.75e-20 Vitiligo; TGCT cis rs3806843 0.576 rs246062 chr5:140324580 T/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs2456568 0.564 rs6483270 chr11:93624380 C/T cg17595323 chr11:93583763 C11orf90 -0.49 -6.48 -0.5 1.95e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg27211696 chr2:191398769 TMEM194B 0.28 5.16 0.42 9.36e-7 Pulse pressure; TGCT cis rs1801251 1.000 rs3817311 chr2:233612557 C/T cg08000102 chr2:233561755 GIGYF2 0.64 6.56 0.51 1.34e-9 Coronary artery disease; TGCT cis rs12210905 1.000 rs72843644 chr6:27211601 A/C cg08851530 chr6:28072375 NA 1.05 5.07 0.41 1.42e-6 Hip circumference adjusted for BMI; TGCT cis rs1008375 0.900 rs6851783 chr4:17578469 A/G cg18681998 chr4:17616180 MED28 0.83 7.51 0.56 1.02e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1784581 0.706 rs9346895 chr6:162431168 T/C cg17173639 chr6:162384350 PARK2 0.42 7.38 0.55 2.03e-11 Itch intensity from mosquito bite; TGCT cis rs3902035 0.964 rs62423993 chr6:119010967 C/T cg07617317 chr6:118971624 C6orf204 0.43 5.01 0.41 1.79e-6 QT interval; TGCT cis rs7312933 0.531 rs2406674 chr12:42720150 T/C cg19980929 chr12:42632907 YAF2 -0.41 -5.76 -0.46 6.3e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs916888 0.773 rs199447 chr17:44812188 C/T cg01570182 chr17:44337453 NA 1.07 9.81 0.66 3.57e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs634534 0.532 rs12794370 chr11:65770413 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.62 6.11 0.48 1.2e-8 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs7949030 0.688 rs2849031 chr11:62365665 G/A cg22862634 chr11:62369728 EML3;MTA2 -0.68 -8.7 -0.62 1.69e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7772486 0.790 rs2249147 chr6:146184999 T/C cg23711669 chr6:146136114 FBXO30 0.93 10.57 0.69 5.33e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs718502 chr6:8527400 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.49e-8 Motion sickness; TGCT cis rs11931598 0.783 rs28385900 chr4:7050836 C/T cg02503808 chr4:7069936 GRPEL1 0.58 5.35 0.43 4.14e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs17376456 0.825 rs17372057 chr5:93071916 C/A cg25358565 chr5:93447407 FAM172A 0.91 8.26 0.6 1.88e-13 Diabetic retinopathy; TGCT trans rs561341 1.000 rs537166 chr17:30326827 C/T cg20587970 chr11:113659929 NA -1.05 -13.02 -0.76 5.98e-25 Hip circumference adjusted for BMI; TGCT cis rs968451 0.526 rs137594 chr22:39691221 G/A cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -4.64 -0.38 8.7e-6 Primary biliary cholangitis; TGCT cis rs6674176 0.932 rs12410334 chr1:44442521 A/C cg13606994 chr1:44402422 ARTN -0.47 -4.7 -0.39 6.93e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1153858 1.000 rs1049503 chr15:45653707 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs57221529 0.766 rs72703065 chr5:588123 C/A cg09021430 chr5:549028 NA -0.37 -4.98 -0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs593982 0.843 rs565267 chr11:65473597 T/C cg08755490 chr11:65554678 OVOL1 1.27 6.79 0.52 4.05e-10 Atopic dermatitis; TGCT cis rs1008375 0.931 rs6449309 chr4:17573208 C/T cg16339924 chr4:17578868 LAP3 0.84 7.48 0.56 1.16e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2723064 0.516 rs17849707 chr2:65298839 A/G cg05010058 chr2:65284262 CEP68 0.47 4.48 0.37 1.67e-5 Atrial fibrillation; TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs2576037 0.545 rs9948405 chr18:44494527 C/G cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.52 -0.38 1.45e-5 Personality dimensions; TGCT cis rs3087591 0.919 rs2018624 chr17:29560777 T/G cg24425628 chr17:29625626 OMG;NF1 -0.49 -7.65 -0.57 4.82e-12 Hip circumference; TGCT cis rs1475911 0.708 rs56185023 chr21:43521538 T/C cg14562523 chr21:43528734 C21orf128;UMODL1 -0.27 -5.33 -0.43 4.5e-7 IgG glycosylation; TGCT cis rs9611565 0.592 rs8779 chr22:42070276 T/C cg06634786 chr22:41940651 POLR3H 0.9 8.74 0.62 1.34e-14 Vitiligo; TGCT cis rs2832191 0.692 rs2254872 chr21:30414724 C/T cg08807101 chr21:30365312 RNF160 0.64 6.01 0.47 1.96e-8 Dental caries; TGCT cis rs3809566 1.000 rs4775610 chr15:63332057 C/T cg08198488 chr15:63333792 TPM1 0.36 5.37 0.43 3.8e-7 Platelet count; TGCT cis rs2933343 0.729 rs1680780 chr3:128612659 G/C cg11901034 chr3:128598214 ACAD9 -0.68 -6.72 -0.52 6.01e-10 IgG glycosylation; TGCT cis rs2688608 0.592 rs2306328 chr10:75579510 C/T cg23231163 chr10:75533350 FUT11 -0.27 -4.64 -0.38 8.56e-6 Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs4699598 chr4:99019158 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.33e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs782590 0.935 rs782652 chr2:55862775 C/A cg03859395 chr2:55845619 SMEK2 0.91 10.87 0.7 9.92e-20 Metabolic syndrome; TGCT cis rs2032447 0.670 rs71557318 chr6:26118570 T/C cg12310025 chr6:25882481 NA 0.51 4.62 0.38 9.56e-6 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs72705030 chr5:645562 C/T cg16624210 chr5:671434 TPPP 0.4 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg06212747 chr3:49208901 KLHDC8B 0.65 6.23 0.49 6.68e-9 Menarche (age at onset); TGCT cis rs3540 0.554 rs4244879 chr15:91066915 C/T cg22089800 chr15:90895588 ZNF774 -0.75 -7.66 -0.57 4.62e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7582180 0.663 rs10199518 chr2:100946041 G/A cg14675211 chr2:100938903 LONRF2 0.47 4.57 0.38 1.16e-5 Intelligence (multi-trait analysis); TGCT cis rs1552244 1.000 rs13319597 chr3:10126312 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 0.48 6.76 0.52 4.82e-10 Alzheimer's disease; TGCT cis rs3774830 1.000 rs3774830 chr4:5440083 A/G cg26943120 chr4:5472116 STK32B -0.22 -4.87 -0.4 3.33e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT trans rs2727020 0.595 rs7924311 chr11:49507573 G/A cg03929089 chr4:120376271 NA -0.76 -9.15 -0.63 1.43e-15 Coronary artery disease; TGCT cis rs7772486 0.790 rs2247429 chr6:146217769 T/C cg05347473 chr6:146136440 FBXO30 0.53 5.08 0.42 1.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2013441 1.000 rs4924808 chr17:20026548 C/T cg18979559 chr17:20280153 CCDC144C -0.42 -4.46 -0.37 1.83e-5 Obesity-related traits; TGCT trans rs7618501 0.966 rs2352974 chr3:49890613 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.96 12.05 0.73 1.29e-22 Intelligence (multi-trait analysis); TGCT cis rs10419226 0.625 rs12980154 chr19:18770119 C/T cg14292368 chr19:18793705 CRTC1 -0.49 -5.42 -0.44 2.98e-7 Barrett's esophagus;Esophageal adenocarcinoma;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs7772486 0.623 rs9485021 chr6:146068797 A/G cg23711669 chr6:146136114 FBXO30 -0.88 -9.63 -0.65 1.01e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs853679 0.527 rs9468333 chr6:28271198 C/T cg18815343 chr6:28367644 ZSCAN12 -0.46 -4.8 -0.4 4.46e-6 Depression; TGCT cis rs909674 0.818 rs5757678 chr22:39843409 A/G cg11247378 chr22:39784982 NA 0.7 8.55 0.61 3.76e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs875971 0.522 rs1968127 chr7:66056803 C/T cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs6570726 0.967 rs450973 chr6:145863065 C/A cg23711669 chr6:146136114 FBXO30 0.7 6.48 0.5 1.9e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs1035144 0.546 rs2215981 chr14:81444967 G/A cg06600135 chr14:81408086 NA -0.48 -4.54 -0.38 1.29e-5 Male sexual orientation; TGCT cis rs4689592 0.587 rs3822269 chr4:7069901 T/C cg25660036 chr4:7070649 GRPEL1 -0.69 -5.98 -0.47 2.21e-8 Monocyte percentage of white cells; TGCT cis rs1334894 1.000 rs7754668 chr6:35590092 G/A cg24281267 chr6:35479648 TULP1 -0.44 -4.73 -0.39 5.95e-6 Coronary artery disease; TGCT cis rs644799 0.965 rs598876 chr11:95560853 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.37e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7954584 0.567 rs1720033 chr12:122384344 C/T cg21016266 chr12:122356598 WDR66 -0.54 -7.02 -0.53 1.26e-10 Mean corpuscular volume; TGCT cis rs478304 0.651 rs948494 chr11:65552118 G/A cg27068330 chr11:65405492 SIPA1 -0.95 -9.42 -0.65 3.25e-16 Acne (severe); TGCT cis rs2293052 0.762 rs549098 chr12:117754327 G/A cg02962597 chr12:117799749 NOS1 0.27 4.87 0.4 3.36e-6 Schizophrenia; TGCT cis rs2228479 0.619 rs78001663 chr16:89896331 C/A cg06558623 chr16:89946397 TCF25 0.55 4.77 0.39 5.13e-6 Skin colour saturation; TGCT cis rs2486012 0.737 rs11210928 chr1:44268219 C/T cg12908607 chr1:44402522 ARTN -0.72 -5.69 -0.45 8.81e-8 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs6980850 chr8:58127204 A/G cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs6088590 1.000 rs6120705 chr20:33313740 T/C cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs3751972 0.590 rs8067428 chr17:26267997 A/G cg02948944 chr17:26242737 NA 0.45 5.54 0.45 1.73e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs763014 0.966 rs15564 chr16:677854 G/T cg09263875 chr16:632152 PIGQ 0.31 6.98 0.53 1.55e-10 Height; TGCT cis rs9549367 0.713 rs3024761 chr13:113824090 C/G cg18105134 chr13:113819100 PROZ 0.47 8.28 0.6 1.71e-13 Platelet distribution width; TGCT cis rs7044106 0.690 rs10739569 chr9:123361027 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.56 5.76 0.46 6.27e-8 Hip circumference adjusted for BMI; TGCT cis rs11112613 0.775 rs10778413 chr12:105962118 G/A cg03607813 chr12:105948248 NA 0.47 5.74 0.46 6.71e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs10838634 1.000 rs4500447 chr11:46776093 A/G cg18332754 chr11:46939436 LRP4 0.84 4.54 0.38 1.29e-5 Schizophrenia; TGCT cis rs734999 0.545 rs12749591 chr1:2563250 G/T cg18854424 chr1:2615690 NA -0.5 -5.95 -0.47 2.54e-8 Ulcerative colitis; TGCT cis rs12142240 0.698 rs72679807 chr1:46846490 G/A cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs7714584 1.000 rs9324660 chr5:150257054 C/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs79349575 0.783 rs62075818 chr17:46982327 T/A cg00947319 chr17:47005597 UBE2Z -0.19 -4.44 -0.37 1.95e-5 Type 2 diabetes; TGCT cis rs3771570 1.000 rs4675811 chr2:242402062 A/T cg21155796 chr2:242212141 HDLBP 0.89 6.85 0.52 3.11e-10 Prostate cancer; TGCT cis rs12142240 0.698 rs10158130 chr1:46822600 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs9527 0.830 rs11191442 chr10:104643596 T/A cg15744005 chr10:104629667 AS3MT -0.5 -6.0 -0.47 1.98e-8 Arsenic metabolism; TGCT cis rs6089829 0.962 rs2314131 chr20:61665225 A/G cg03213289 chr20:61660250 NA 0.59 6.97 0.53 1.7e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1372520 0.684 rs1837891 chr4:90736131 C/G cg01966878 chr4:90757139 SNCA 0.31 4.81 0.4 4.3e-6 Neuroticism; TGCT cis rs9303401 0.659 rs12944971 chr17:56988801 A/T cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.16 0.48 9.11e-9 Cognitive test performance; TGCT cis rs2153535 0.541 rs9328477 chr6:8519109 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs9357506 1.000 rs62402365 chr6:46318800 G/T cg21115430 chr6:46460003 NA -0.24 -4.76 -0.39 5.19e-6 Body mass index; TGCT cis rs9303401 0.573 rs34717648 chr17:56886624 T/A cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs11722228 1.000 rs6825187 chr4:9915325 T/C cg11266682 chr4:10021025 SLC2A9 -0.48 -5.38 -0.44 3.55e-7 Gout;Urate levels;Serum uric acid levels; TGCT cis rs796364 0.662 rs11688415 chr2:201143409 C/T cg17644776 chr2:200775616 C2orf69 0.37 5.05 0.41 1.54e-6 Schizophrenia; TGCT cis rs7772486 0.875 rs9390377 chr6:146386932 G/A cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 0.739 rs6922 chr6:86205323 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.59 5.15 0.42 1.01e-6 Response to antipsychotic treatment; TGCT cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg17747265 chr1:1875780 NA -0.42 -8.11 -0.59 4.15e-13 Body mass index; TGCT cis rs1348850 0.914 rs12612857 chr2:178467144 A/G cg22681709 chr2:178499509 PDE11A -0.43 -5.2 -0.42 8e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs12935418 0.583 rs7206625 chr16:80964433 G/A cg07676361 chr16:80966860 NA -0.35 -4.66 -0.39 8.02e-6 Mean corpuscular volume; TGCT cis rs9916302 0.904 rs11078897 chr17:37415870 C/T cg15445000 chr17:37608096 MED1 0.33 4.84 0.4 3.8e-6 Glomerular filtration rate (creatinine); TGCT cis rs56235845 0.964 rs4075958 chr5:176784512 A/G cg06060754 chr5:176797920 RGS14 -0.59 -10.59 -0.69 4.56e-19 Hemoglobin concentration;Hematocrit; TGCT cis rs9902453 0.935 rs9911794 chr17:28349466 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs1018836 0.632 rs7002775 chr8:91476765 C/T cg16814680 chr8:91681699 NA 0.77 8.01 0.58 7.13e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2721195 0.967 rs1985022 chr8:145684031 C/T cg17328964 chr8:145687451 CYHR1 -0.53 -8.06 -0.59 5.36e-13 Age at first birth; TGCT cis rs17133449 0.718 rs7923564 chr10:4753292 G/A cg04530666 chr10:3759553 NA -0.28 -4.68 -0.39 7.48e-6 Major depressive disorder; TGCT cis rs137699 0.959 rs5757631 chr22:39755953 T/C cg05872129 chr22:39784769 NA -0.56 -4.85 -0.4 3.64e-6 IgG glycosylation; TGCT cis rs9341808 0.718 rs9352803 chr6:80864667 G/T cg08355045 chr6:80787529 NA 0.31 5.53 0.44 1.79e-7 Sitting height ratio; TGCT cis rs9902453 0.765 rs8079209 chr17:28186773 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.88 8.7 0.62 1.65e-14 Coffee consumption (cups per day); TGCT trans rs62103177 0.713 rs3744886 chr18:77659561 G/T cg05926928 chr17:57297772 GDPD1 1.21 11.0 0.7 4.67e-20 Opioid sensitivity; TGCT cis rs752010 0.619 rs7539238 chr1:42113572 A/C cg06885757 chr1:42089581 HIVEP3 0.29 5.07 0.41 1.41e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs7772486 0.902 rs1125462 chr6:146417832 A/G cg23711669 chr6:146136114 FBXO30 0.79 8.32 0.6 1.37e-13 Lobe attachment (rater-scored or self-reported); TGCT cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg12667521 chr19:29218732 NA 0.53 5.64 0.45 1.07e-7 Methadone dose in opioid dependence; TGCT cis rs6952808 1.000 rs4721122 chr7:1893311 C/G cg22963979 chr7:1858916 MAD1L1 -0.34 -5.41 -0.44 3.05e-7 Bipolar disorder and schizophrenia; TGCT cis rs7255045 0.752 rs55730975 chr19:12973039 G/A cg06537894 chr19:12978706 MAST1 -0.49 -4.48 -0.37 1.69e-5 Mean corpuscular volume; TGCT cis rs10178094 0.669 rs7595982 chr2:161332385 T/G cg03641300 chr2:160917029 PLA2R1 -0.22 -4.77 -0.39 5.05e-6 White blood cell count; TGCT cis rs3749237 0.595 rs2878298 chr3:49406080 T/C cg07636037 chr3:49044803 WDR6 0.63 6.04 0.48 1.67e-8 Resting heart rate; TGCT cis rs57221529 0.766 rs58015612 chr5:580665 A/T cg09021430 chr5:549028 NA -0.37 -5.35 -0.43 4.16e-7 Lung disease severity in cystic fibrosis; TGCT cis rs9581857 0.579 rs2780341 chr13:27996401 C/T cg22138327 chr13:27999177 GTF3A -0.83 -5.75 -0.46 6.62e-8 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs71435601 0.574 rs547239 chr2:21384686 T/A cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs611744 0.935 rs679077 chr8:109244742 G/T cg21045802 chr8:109455806 TTC35 0.5 4.57 0.38 1.18e-5 Dupuytren's disease; TGCT cis rs1218582 0.741 rs4339857 chr1:154888962 A/G cg06221963 chr1:154839813 KCNN3 -0.75 -12.65 -0.75 4.66e-24 Prostate cancer; TGCT cis rs6088590 0.930 rs6120723 chr20:33364655 C/T cg06115741 chr20:33292138 TP53INP2 0.67 5.6 0.45 1.34e-7 Coronary artery disease; TGCT cis rs9527 0.830 rs11191442 chr10:104643596 T/A cg04362960 chr10:104952993 NT5C2 0.61 4.96 0.41 2.26e-6 Arsenic metabolism; TGCT cis rs17741873 0.779 rs10509346 chr10:75596014 A/G cg07699608 chr10:75541558 CHCHD1 -0.72 -5.15 -0.42 1.02e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs1371867 0.846 rs2047249 chr8:101234126 A/G cg06636551 chr8:101224915 SPAG1 0.4 5.03 0.41 1.66e-6 Atrioventricular conduction; TGCT cis rs7175404 0.536 rs79719082 chr15:94038436 A/G cg08478250 chr15:93957936 NA 0.36 4.77 0.39 5.11e-6 Attention deficit hyperactivity disorder; TGCT cis rs2180341 1.000 rs6569479 chr6:127606588 A/G cg24812749 chr6:127587940 RNF146 0.91 6.98 0.53 1.56e-10 Breast cancer; TGCT cis rs6087990 0.865 rs6058859 chr20:31335157 A/G cg13636640 chr20:31349939 DNMT3B 1.01 14.09 0.78 1.66e-27 Ulcerative colitis; TGCT cis rs12136530 0.744 rs12090885 chr1:19779781 G/A cg18923740 chr1:19971790 NBL1 0.38 4.65 0.39 8.48e-6 Lead levels in blood; TGCT cis rs9394841 0.692 rs34073739 chr6:41829970 A/G cg08135965 chr6:41755394 TOMM6 0.52 4.82 0.4 4.13e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs9611565 0.512 rs6002474 chr22:42168181 A/G cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs727479 0.502 rs10046 chr15:51502986 G/A cg19946085 chr15:51559439 CYP19A1 -0.31 -4.53 -0.38 1.39e-5 Estradiol levels; TGCT cis rs17253792 0.822 rs80321745 chr14:56162947 T/A cg01858014 chr14:56050164 KTN1 -0.35 -4.47 -0.37 1.73e-5 Putamen volume; TGCT cis rs9611565 0.512 rs5751148 chr22:42139078 A/G cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Vitiligo; TGCT cis rs10992471 0.603 rs10761160 chr9:95208701 A/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.67 -0.45 9.42e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs4383453 0.520 rs6790286 chr3:123103037 G/A cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs12681288 0.644 rs2600494 chr8:1025517 C/T cg04851639 chr8:1020857 NA -0.36 -6.82 -0.52 3.56e-10 Schizophrenia; TGCT cis rs10504229 0.906 rs7842855 chr8:58167718 G/C cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs4900538 0.855 rs12587464 chr14:102886561 G/C cg18135206 chr14:102964638 TECPR2 -0.2 -4.57 -0.38 1.18e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4654899 0.643 rs12145181 chr1:21086046 C/A cg01072550 chr1:21505969 NA -0.54 -8.85 -0.62 7.34e-15 Superior frontal gyrus grey matter volume; TGCT cis rs4786125 0.665 rs8060329 chr16:6908864 G/A cg03623568 chr16:6915990 A2BP1 -0.41 -6.06 -0.48 1.5e-8 Heart rate variability traits (SDNN); TGCT cis rs6088590 0.930 rs6087618 chr20:33288407 C/T cg06115741 chr20:33292138 TP53INP2 0.66 5.62 0.45 1.19e-7 Coronary artery disease; TGCT cis rs12600635 0.564 rs80068883 chr17:17107854 C/T cg16928487 chr17:17741425 SREBF1 0.38 4.94 0.41 2.46e-6 IgG glycosylation; TGCT cis rs35160687 0.901 rs12622200 chr2:86498595 A/G cg12542933 chr2:85804724 VAMP8 -0.39 -4.7 -0.39 6.7e-6 Night sleep phenotypes; TGCT cis rs8072100 0.840 rs9912311 chr17:45547132 T/C cg08085267 chr17:45401833 C17orf57 -0.46 -5.07 -0.41 1.39e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2342371 0.848 rs12632592 chr3:196219365 G/A cg15048948 chr3:196158458 UBXN7 0.53 4.49 0.37 1.6e-5 Fat distribution (HIV); TGCT cis rs4794202 0.629 rs16948662 chr17:45913847 C/A cg02219949 chr17:45927392 SP6 0.42 4.52 0.38 1.4e-5 Alzheimer's disease (cognitive decline); TGCT cis rs2115630 0.691 rs61322921 chr15:85163638 T/C cg12863693 chr15:85201151 NMB -0.4 -5.42 -0.44 2.96e-7 P wave terminal force; TGCT cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10992471 0.603 rs12336884 chr9:95234183 A/C cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.79 -0.46 5.39e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6688613 1.000 rs1327866 chr1:166952910 C/T cg07049167 chr1:166818506 POGK -0.22 -4.63 -0.38 8.97e-6 Refractive astigmatism; TGCT cis rs909002 0.849 rs871634 chr1:32093167 G/C cg11573219 chr1:32083031 HCRTR1 -0.46 -5.93 -0.47 2.77e-8 Intelligence (multi-trait analysis); TGCT cis rs4788570 0.625 rs4788810 chr16:71621637 C/T cg06353428 chr16:71660113 MARVELD3 -1.46 -12.42 -0.74 1.67e-23 Intelligence (multi-trait analysis); TGCT cis rs10876993 0.890 rs1689584 chr12:58081478 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.98 -0.47 2.25e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs12188164 1.000 rs72717412 chr5:429381 C/T cg26850624 chr5:429559 AHRR -0.2 -4.81 -0.4 4.22e-6 Cystic fibrosis severity; TGCT cis rs1998418 0.599 rs7086834 chr10:126357963 C/A cg03585084 chr10:126284563 LHPP -0.27 -5.07 -0.41 1.4e-6 Mean platelet volume; TGCT cis rs9389248 0.690 rs728030 chr6:135246294 G/T cg24558204 chr6:135376177 HBS1L -0.47 -4.8 -0.4 4.41e-6 High light scatter reticulocyte percentage of red cells; TGCT cis rs12220238 0.822 rs73286281 chr10:76083337 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.88 5.98 0.47 2.22e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2120019 0.567 rs68036747 chr15:75203200 A/C cg09165964 chr15:75287851 SCAMP5 -0.89 -6.78 -0.52 4.42e-10 Blood trace element (Zn levels); TGCT cis rs1218582 0.772 rs6683557 chr1:154852307 C/G cg06221963 chr1:154839813 KCNN3 -0.76 -13.04 -0.76 5.27e-25 Prostate cancer; TGCT cis rs2243480 1.000 rs73142122 chr7:65311298 C/A cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs651907 0.557 rs3094297 chr3:101399260 A/G cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.76 -0.52 4.83e-10 Colorectal cancer; TGCT cis rs9611519 0.894 rs9623320 chr22:41478482 G/A cg03806693 chr22:41940476 POLR3H -0.65 -5.91 -0.47 3.04e-8 Neuroticism; TGCT cis rs9914544 1.000 rs9916245 chr17:18766825 C/G cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.41 1.36e-6 Educational attainment (years of education); TGCT cis rs6671200 1.000 rs6671200 chr1:95697529 A/C cg26537280 chr1:95699037 RWDD3 -0.7 -5.55 -0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs739401 0.611 rs2071104 chr11:3036933 G/T cg25174290 chr11:3078921 CARS 0.47 4.68 0.39 7.52e-6 Longevity; TGCT cis rs4862750 0.872 rs6553030 chr4:187899234 T/C cg22105103 chr4:187893119 NA 0.35 4.89 0.4 3.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7681440 0.904 rs7680761 chr4:90763510 A/T cg14346243 chr4:90757452 SNCA -0.59 -5.74 -0.46 6.82e-8 Dementia with Lewy bodies; TGCT cis rs12220238 1.000 rs10824129 chr10:76008855 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.91 0.58 1.21e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9300255 0.602 rs2510885 chr12:123614813 G/C cg00376283 chr12:123451042 ABCB9 0.71 5.61 0.45 1.26e-7 Neutrophil percentage of white cells; TGCT cis rs263156 0.770 rs263121 chr6:142894300 T/C cg18419694 chr6:143832440 FUCA2 -0.39 -4.46 -0.37 1.81e-5 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs3741151 1.000 rs79778136 chr11:73041339 T/C cg17517138 chr11:73019481 ARHGEF17 0.97 4.76 0.39 5.22e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs7264396 0.790 rs2425160 chr20:34425968 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.83 -0.4 3.89e-6 Total cholesterol levels; TGCT cis rs617219 0.597 rs10474581 chr5:78578884 G/A cg09550809 chr5:78407562 BHMT -0.4 -5.49 -0.44 2.19e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs796364 1.000 rs281783 chr2:200751582 G/A cg17644776 chr2:200775616 C2orf69 0.31 4.83 0.4 3.99e-6 Schizophrenia; TGCT cis rs40363 0.729 rs6501176 chr16:3522197 A/G cg21433313 chr16:3507492 NAT15 -0.36 -4.94 -0.41 2.5e-6 Tuberculosis; TGCT cis rs1865760 0.613 rs7749342 chr6:25920265 T/C cg03264133 chr6:25882463 NA -0.46 -4.72 -0.39 6.36e-6 Height; TGCT cis rs1552244 0.938 rs9873794 chr3:10074153 T/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.18 -0.49 8.51e-9 Alzheimer's disease; TGCT cis rs13191362 1.000 rs60719662 chr6:163006643 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs36051895 0.664 rs17425819 chr9:5114773 C/T cg02405213 chr9:5042618 JAK2 -0.69 -8.88 -0.62 6.38e-15 Pediatric autoimmune diseases; TGCT cis rs9467711 0.606 rs28360517 chr6:26602453 A/G cg16898833 chr6:26189333 HIST1H4D 1.02 5.25 0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7833790 0.553 rs9693128 chr8:82706128 A/G cg06027949 chr8:82754900 SNX16 -0.68 -5.6 -0.45 1.31e-7 Diastolic blood pressure; TGCT cis rs1218582 0.661 rs4845695 chr1:154911798 A/G cg09359103 chr1:154839909 KCNN3 -0.64 -12.27 -0.74 3.87e-23 Prostate cancer; TGCT cis rs3818285 0.556 rs944966 chr10:111658334 C/G cg00817464 chr10:111662876 XPNPEP1 -0.29 -4.97 -0.41 2.14e-6 Superior crus of antihelix expression; TGCT cis rs12681287 0.547 rs13249177 chr8:87513034 A/G cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs9611519 0.780 rs3171692 chr22:41642212 C/T cg13695892 chr22:41940480 POLR3H -0.61 -5.61 -0.45 1.24e-7 Neuroticism; TGCT cis rs3749237 0.595 rs6797765 chr3:49423976 A/G cg03060546 chr3:49711283 APEH 0.77 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs853679 0.517 rs9393891 chr6:28079160 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs904251 0.797 rs1776460 chr6:37485484 A/G cg08126542 chr6:37504118 NA -0.4 -5.41 -0.44 3.12e-7 Cognitive performance; TGCT cis rs2836974 0.863 rs1065242 chr21:40567716 C/G cg06238570 chr21:40685208 BRWD1 0.7 6.45 0.5 2.3e-9 Cognitive function; TGCT cis rs10875595 0.836 rs10062604 chr5:140661932 T/C cg20560182 chr5:140700478 TAF7 -0.66 -5.06 -0.41 1.49e-6 Pulmonary function decline; TGCT cis rs1395 0.677 rs113353646 chr2:27492674 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.69 9.17 0.64 1.29e-15 Blood metabolite levels; TGCT cis rs2236918 0.687 rs1776136 chr1:242026845 G/A cg04158730 chr1:242011433 EXO1 0.56 5.36 0.43 3.88e-7 Menopause (age at onset); TGCT cis rs7568458 0.905 rs59877521 chr2:85759494 C/T cg02493740 chr2:85810744 VAMP5 -0.27 -4.86 -0.4 3.53e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs57221529 0.766 rs56216231 chr5:581193 G/A cg20362242 chr5:692897 TPPP 0.5 4.88 0.4 3.21e-6 Lung disease severity in cystic fibrosis; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs1941023 0.584 rs2014121 chr11:60156297 T/C cg08716584 chr11:60157161 MS4A7 -0.35 -5.29 -0.43 5.3e-7 Congenital heart disease (maternal effect); TGCT trans rs524675 0.581 rs473124 chr4:13956897 A/G cg02315626 chr17:27188560 MIR451;MIR144 0.42 6.87 0.53 2.82e-10 Amyotrophic lateral sclerosis in C9orf72 mutation negative individuals; TGCT trans rs916888 0.647 rs199523 chr17:44848517 C/A cg01341218 chr17:43662625 NA -0.86 -7.5 -0.56 1.06e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10875746 0.551 rs2054903 chr12:48724493 C/T cg20731937 chr12:48336164 NA 0.55 5.04 0.41 1.6e-6 Longevity (90 years and older); TGCT cis rs9393692 0.905 rs6916289 chr6:26289122 A/T cg13736514 chr6:26305472 NA -0.37 -5.42 -0.44 3.01e-7 Educational attainment; TGCT cis rs709400 0.663 rs3783402 chr14:103967929 C/G cg26031613 chr14:104095156 KLC1 0.84 9.5 0.65 2.08e-16 Body mass index; TGCT cis rs939658 0.805 rs59104559 chr15:79438784 A/G cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs75059851 0.756 rs11223648 chr11:133840412 C/T cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs1799949 0.930 rs4445938 chr17:41337900 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs4595586 0.967 rs56149694 chr12:39263771 T/C cg10518543 chr12:38710700 ALG10B -0.51 -5.09 -0.42 1.31e-6 Morning vs. evening chronotype; TGCT cis rs7909074 1.000 rs6593447 chr10:45400235 G/A cg05187965 chr10:45406764 TMEM72 -0.24 -5.02 -0.41 1.73e-6 Mean corpuscular volume; TGCT cis rs231513 0.954 rs170766 chr17:41963407 C/G cg26893861 chr17:41843967 DUSP3 -0.71 -5.21 -0.42 7.57e-7 Cognitive function; TGCT cis rs7542091 0.635 rs7550733 chr1:210044968 G/A cg21951975 chr1:209979733 IRF6 0.6 6.11 0.48 1.18e-8 Monobrow; TGCT cis rs7727544 0.735 rs273913 chr5:131661156 A/G cg24060327 chr5:131705240 SLC22A5 -0.43 -4.45 -0.37 1.92e-5 Blood metabolite levels; TGCT cis rs7666738 0.830 rs28795113 chr4:98951331 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 0.830 rs778711 chr7:65851657 G/A cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs9303401 0.659 rs11079358 chr17:56920949 G/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs59698941 0.943 rs66628697 chr5:132252561 C/T cg27099455 chr5:132201840 GDF9;UQCRQ 0.37 4.47 0.37 1.74e-5 Apolipoprotein A-IV levels; TGCT cis rs7312933 0.558 rs1669886 chr12:42838240 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.7 -0.46 8.41e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg07424592 chr7:64974309 NA 1.25 7.49 0.56 1.15e-11 Diabetic kidney disease; TGCT cis rs3820068 0.705 rs4646103 chr1:15819827 T/A cg05660106 chr1:15850417 CASP9 1.15 14.12 0.79 1.41e-27 Systolic blood pressure; TGCT cis rs35146811 0.700 rs858513 chr7:99825558 G/A cg00553149 chr7:99775558 STAG3;GPC2 -0.32 -4.81 -0.4 4.28e-6 Coronary artery disease; TGCT cis rs12477438 0.520 rs2516830 chr2:99773702 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.75 7.25 0.55 3.92e-11 Chronic sinus infection; TGCT cis rs3820928 1.000 rs10197757 chr2:227763244 A/C cg11843606 chr2:227700838 RHBDD1 -0.53 -4.69 -0.39 7.22e-6 Pulmonary function; TGCT cis rs832540 0.669 rs832539 chr5:56199386 A/C cg12311346 chr5:56204834 C5orf35 -0.61 -6.24 -0.49 6.33e-9 Coronary artery disease; TGCT cis rs933688 1.000 rs2059208 chr5:90732065 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 9.76 0.66 4.82e-17 Smoking behavior; TGCT cis rs875971 0.965 rs697968 chr7:65535033 G/A cg11764359 chr7:65958608 NA -0.56 -4.7 -0.39 6.74e-6 Aortic root size; TGCT cis rs56399783 0.901 rs73049362 chr7:2826822 G/A cg19731401 chr7:2775893 GNA12 0.37 5.15 0.42 1e-6 Childhood ear infection; TGCT cis rs6952808 0.929 rs11768206 chr7:1932151 T/G cg04267008 chr7:1944627 MAD1L1 -0.36 -4.88 -0.4 3.23e-6 Bipolar disorder and schizophrenia; TGCT cis rs9467773 1.000 rs9357010 chr6:26527945 C/G cg15659132 chr6:26577336 NA 0.85 12.22 0.74 5.02e-23 Intelligence (multi-trait analysis); TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg16325326 chr1:53192061 ZYG11B -0.57 -6.39 -0.5 2.97e-9 Monocyte count; TGCT cis rs916888 0.610 rs199529 chr17:44837217 A/C cg16520312 chr17:43971471 MAPT;LOC100128977 -0.56 -4.9 -0.4 2.93e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9399135 0.507 rs2072825 chr6:135253451 A/G cg22676075 chr6:135203613 NA -0.51 -5.11 -0.42 1.17e-6 Red blood cell count; TGCT cis rs6540559 0.673 rs7550857 chr1:209956542 C/A cg22029157 chr1:209979665 IRF6 0.76 5.58 0.45 1.41e-7 Cleft lip with or without cleft palate; TGCT cis rs4268898 0.760 rs11676939 chr2:24479057 C/T cg02683114 chr2:24398427 C2orf84 0.2 4.98 0.41 2.1e-6 Asthma; TGCT cis rs922182 0.554 rs9972387 chr15:64191485 A/G cg02919090 chr15:64263738 DAPK2 0.33 5.94 0.47 2.71e-8 Blood protein levels; TGCT cis rs7267979 0.844 rs35735333 chr20:25337205 T/G cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs651907 0.557 rs11925001 chr3:101373966 C/T cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs9467773 0.620 rs1490488 chr6:26614808 T/C cg02458000 chr6:26745757 NA 0.55 5.29 0.43 5.31e-7 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.560 rs4919664 chr10:104363408 A/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6435161 0.762 rs933969 chr2:203499720 G/A cg18429434 chr2:203499731 FAM117B 0.53 5.19 0.42 8.43e-7 Total cholesterol levels; TGCT cis rs12762955 0.507 rs10737004 chr10:1039019 T/C cg20503657 chr10:835505 NA -0.42 -5.47 -0.44 2.42e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs3015497 0.789 rs1389652 chr14:51125240 T/C cg04730355 chr14:51134070 SAV1 -0.6 -5.81 -0.46 5.04e-8 Mean platelet volume; TGCT cis rs4242434 0.819 rs720745 chr8:22471147 G/T cg03733263 chr8:22462867 KIAA1967 1.08 17.0 0.84 3.37e-34 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs10504229 0.871 rs60342323 chr8:58154899 T/C cg22535103 chr8:58192502 C8orf71 -0.39 -4.69 -0.39 7.13e-6 Developmental language disorder (linguistic errors); TGCT cis rs981844 0.961 rs62325084 chr4:154662603 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT trans rs17471911 0.708 rs80240449 chr10:100754725 T/C cg03484267 chr2:207988651 KLF7 -0.53 -6.79 -0.52 4.24e-10 Neuroticism; TGCT cis rs11098499 0.562 rs58583086 chr4:120556362 A/G cg09307838 chr4:120376055 NA -0.57 -5.45 -0.44 2.59e-7 Corneal astigmatism; TGCT cis rs3741404 0.620 rs2236648 chr11:63964657 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 8.1 0.59 4.29e-13 Platelet count; TGCT cis rs765787 0.530 rs4775832 chr15:45534828 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs7192750 0.562 rs152838 chr16:72105702 C/T cg06353428 chr16:71660113 MARVELD3 1.03 5.31 0.43 4.93e-7 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs694739 0.796 rs479777 chr11:64107477 A/G cg23796481 chr11:64053134 BAD;GPR137 0.55 5.47 0.44 2.41e-7 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs6061231 0.755 rs11699160 chr20:60958651 T/C cg24112000 chr20:60950667 NA -0.34 -5.07 -0.41 1.38e-6 Colorectal cancer; TGCT cis rs2239547 0.657 rs3755803 chr3:52866157 C/G cg11645453 chr3:52864694 ITIH4 0.35 5.75 0.46 6.41e-8 Schizophrenia; TGCT cis rs9549367 0.713 rs3024747 chr13:113821787 C/G cg00898013 chr13:113819073 PROZ -0.53 -6.74 -0.52 5.25e-10 Platelet distribution width; TGCT cis rs903263 0.841 rs1874070 chr1:84599276 T/C cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.69e-6 Breast cancer (male); TGCT cis rs55794721 0.509 rs2982358 chr1:25745204 G/T cg00786635 chr1:25594202 NA 0.58 6.07 0.48 1.43e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs2797160 0.547 rs10872298 chr6:125956348 A/C cg05901451 chr6:126070800 HEY2 -0.62 -5.17 -0.42 9.25e-7 Endometrial cancer; TGCT cis rs7172809 0.573 rs3784787 chr15:77681010 T/C cg22256960 chr15:77711686 NA -0.5 -4.74 -0.39 5.82e-6 Glucose homeostasis traits; TGCT cis rs9549367 0.789 rs6577031 chr13:113878182 T/C cg00898013 chr13:113819073 PROZ 0.41 5.19 0.42 8.21e-7 Platelet distribution width; TGCT cis rs9640161 0.742 rs11767726 chr7:150018096 A/C cg17279839 chr7:150038598 RARRES2 -0.43 -4.55 -0.38 1.28e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2075165 0.870 rs9943105 chr1:156245245 T/C cg16558208 chr1:156270281 VHLL 0.27 4.83 0.4 3.87e-6 Tonsillectomy; TGCT cis rs1023500 0.551 rs2854837 chr22:42458481 G/A cg05082376 chr22:42548792 NA -0.22 -5.31 -0.43 4.85e-7 Schizophrenia; TGCT cis rs7255045 0.788 rs8110185 chr19:12959827 T/A cg23899408 chr19:12877188 HOOK2 -0.61 -4.99 -0.41 1.97e-6 Mean corpuscular volume; TGCT cis rs2228479 0.867 rs62056110 chr16:89946388 A/C cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs3733585 0.631 rs4697707 chr4:10119787 G/T cg11266682 chr4:10021025 SLC2A9 -0.55 -6.35 -0.5 3.78e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10504229 1.000 rs66495524 chr8:58187365 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7586879 0.681 rs28836469 chr2:25117215 A/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs1865760 0.892 rs2328903 chr6:25935765 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.15 0.48 9.9e-9 Height; TGCT cis rs4788570 0.584 rs11075898 chr16:71705215 T/C cg06353428 chr16:71660113 MARVELD3 1.56 12.54 0.75 8.54e-24 Intelligence (multi-trait analysis); TGCT cis rs6840360 0.615 rs113052419 chr4:152473008 T/C cg17479576 chr4:152424074 FAM160A1 -0.72 -7.75 -0.57 2.8e-12 Intelligence (multi-trait analysis); TGCT cis rs2933343 0.729 rs1683816 chr3:128651195 G/T cg11901034 chr3:128598214 ACAD9 0.65 6.29 0.49 5.07e-9 IgG glycosylation; TGCT cis rs7226408 0.857 rs55895201 chr18:34478630 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs939574 0.722 rs72955435 chr2:220087354 A/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.11 5.34 0.43 4.31e-7 Platelet distribution width; TGCT cis rs4819052 0.851 rs4819040 chr21:46659762 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 6.31 0.49 4.41e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs597539 0.652 rs579136 chr11:68637476 C/G cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs4851266 1.000 rs11695383 chr2:100826098 G/T cg22139774 chr2:100720529 AFF3 -0.35 -5.19 -0.42 8.51e-7 Educational attainment; TGCT cis rs17270561 0.779 rs17271767 chr6:25886921 C/T cg16482183 chr6:26056742 HIST1H1C 0.89 6.63 0.51 9.23e-10 Iron status biomarkers; TGCT cis rs709400 0.526 rs11622473 chr14:103979762 G/A cg12935359 chr14:103987150 CKB -0.49 -6.55 -0.51 1.37e-9 Body mass index; TGCT cis rs2629540 0.824 rs1552345 chr10:126477406 A/G cg08799069 chr10:126477246 METTL10 -0.31 -4.68 -0.39 7.26e-6 Cocaine dependence; TGCT cis rs763121 0.744 rs5757140 chr22:38957013 T/C cg06022373 chr22:39101656 GTPBP1 0.81 7.86 0.58 1.58e-12 Menopause (age at onset); TGCT cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg04317338 chr11:64019027 PLCB3 0.8 6.61 0.51 1.01e-9 Mean platelet volume; TGCT cis rs1971762 0.545 rs7297461 chr12:54047178 A/T cg16917193 chr12:54089295 NA 1.08 11.48 0.72 3.21e-21 Height; TGCT cis rs3796352 0.667 rs34860124 chr3:52857778 T/A cg15956490 chr3:53032818 SFMBT1 0.55 4.9 0.4 2.93e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs2243480 1.000 rs778691 chr7:65873092 G/C cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs62244186 0.516 rs11922470 chr3:44777795 C/T cg02073558 chr3:44770973 ZNF501 0.96 10.79 0.7 1.5e-19 Depressive symptoms; TGCT cis rs11190604 1.000 rs11190555 chr10:102209160 A/G cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6906287 0.647 rs6569015 chr6:118686344 C/T cg21191810 chr6:118973309 C6orf204 0.26 4.46 0.37 1.85e-5 Electrocardiographic conduction measures; TGCT cis rs875971 0.830 rs427575 chr7:65519219 A/G cg18876405 chr7:65276391 NA 0.33 4.97 0.41 2.14e-6 Aortic root size; TGCT cis rs7085104 0.660 rs3781286 chr10:104595719 C/T cg15744005 chr10:104629667 AS3MT -0.43 -5.48 -0.44 2.26e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs2658782 0.789 rs2658773 chr11:93126914 A/G cg18152523 chr11:93063302 CCDC67 -0.58 -4.6 -0.38 1.03e-5 Pulmonary function decline; TGCT cis rs9534288 0.699 rs1409432 chr13:46668302 C/T cg15192986 chr13:46630673 CPB2 -0.49 -6.05 -0.48 1.62e-8 Blood protein levels; TGCT trans rs2440129 0.963 rs12325805 chr17:6912219 T/G cg18731024 chr5:2998264 NA 0.83 6.74 0.52 5.4e-10 Tonsillectomy; TGCT trans rs3780486 0.505 rs1411609 chr9:33137303 C/T cg20290983 chr6:43655470 MRPS18A 0.79 8.48 0.61 5.68e-14 IgG glycosylation; TGCT cis rs2730260 0.537 rs73169233 chr7:158882201 C/T cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs2797160 1.000 rs1578794 chr6:126015469 T/C cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs17401966 0.931 rs11585794 chr1:10443867 G/A cg19773385 chr1:10388646 KIF1B -0.24 -5.49 -0.44 2.16e-7 Hepatocellular carcinoma; TGCT cis rs3091242 0.933 rs7541095 chr1:25761291 T/C cg23205692 chr1:25664452 TMEM50A 0.47 4.89 0.4 3.04e-6 Erythrocyte sedimentation rate; TGCT cis rs453301 0.686 rs28482034 chr8:8869664 G/A cg00184457 chr8:8946301 NA -0.27 -4.92 -0.4 2.72e-6 Joint mobility (Beighton score); TGCT cis rs597539 0.690 rs552517 chr11:68625286 T/G cg06112835 chr11:68658793 MRPL21 0.5 8.25 0.6 1.92e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9807989 0.839 rs10206753 chr2:102968362 T/C cg09003973 chr2:102972529 NA 0.64 5.7 0.46 8.28e-8 Asthma; TGCT cis rs6831352 0.918 rs13127153 chr4:100058121 C/T cg12011299 chr4:100065546 ADH4 -0.41 -4.96 -0.41 2.29e-6 Alcohol dependence; TGCT cis rs58688157 0.883 rs34793529 chr11:575800 T/G cg16486109 chr11:613632 IRF7 0.33 4.73 0.39 6.05e-6 Systemic lupus erythematosus; TGCT cis rs74054849 0.541 rs12094673 chr1:15914820 T/C cg05660106 chr1:15850417 CASP9 0.93 5.88 0.47 3.61e-8 Alcoholic chronic pancreatitis; TGCT cis rs9902453 0.817 rs1038089 chr17:28178724 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.18 0.54 5.62e-11 Coffee consumption (cups per day); TGCT cis rs739496 0.744 rs848130 chr12:112009831 G/A cg10833066 chr12:111807467 FAM109A 0.37 5.38 0.44 3.53e-7 Platelet count; TGCT cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.85 -0.4 3.62e-6 Bipolar disorder; TGCT cis rs10504229 0.953 rs17805380 chr8:58171128 C/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9399135 0.967 rs12661423 chr6:135349570 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.93 0.4 2.62e-6 Red blood cell count; TGCT cis rs763121 0.626 rs5757236 chr22:39073824 T/C cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs12532214 0.617 rs73673328 chr7:3149140 G/C cg19214707 chr7:3157722 NA -0.4 -4.88 -0.4 3.17e-6 Itch intensity from mosquito bite; TGCT cis rs2224391 0.534 rs2773308 chr6:5246833 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs8017423 0.935 rs3783838 chr14:90733012 A/G cg04374321 chr14:90722782 PSMC1 -0.75 -7.24 -0.54 4.19e-11 Mortality in heart failure; TGCT cis rs9486719 0.947 rs6916232 chr6:96985959 A/T cg18709589 chr6:96969512 KIAA0776 0.72 5.28 0.43 5.64e-7 Migraine;Coronary artery disease; TGCT cis rs6951245 0.554 rs35126802 chr7:1134842 C/T cg18402987 chr7:1209562 NA 0.48 4.79 0.39 4.72e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2688608 0.592 rs7909802 chr10:75484186 G/C cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs8002180 0.921 rs4771910 chr13:95929888 C/T cg24476569 chr13:95954382 ABCC4 -0.39 -4.82 -0.4 4.05e-6 Blood metabolite levels; TGCT trans rs1005277 0.505 rs1208689 chr10:38097775 C/G cg17830980 chr10:43048298 ZNF37B -0.72 -8.22 -0.59 2.27e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7959452 0.640 rs4761233 chr12:69722880 T/C cg11871910 chr12:69753446 YEATS4 0.63 6.42 0.5 2.69e-9 Blood protein levels; TGCT cis rs9911578 1.000 rs9898916 chr17:57048660 C/T cg12560992 chr17:57184187 TRIM37 0.76 9.29 0.64 6.74e-16 Intelligence (multi-trait analysis); TGCT cis rs9393692 0.875 rs6939589 chr6:26289203 C/T cg05868516 chr6:26286170 HIST1H4H -0.63 -5.88 -0.47 3.5e-8 Educational attainment; TGCT cis rs854765 0.547 rs4584886 chr17:17896205 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.78 8.07 0.59 5.28e-13 Total body bone mineral density; TGCT trans rs4650994 0.623 rs7534394 chr1:178622760 G/A cg05059571 chr16:84539110 KIAA1609 0.41 7.14 0.54 7.07e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs769267 0.895 rs2905435 chr19:19495954 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.62 -5.25 -0.43 6.3e-7 Tonsillectomy; TGCT cis rs11098499 0.562 rs13101722 chr4:120555975 C/A cg09307838 chr4:120376055 NA -0.57 -5.3 -0.43 5.13e-7 Corneal astigmatism; TGCT cis rs6688613 1.000 rs6699159 chr1:166946072 T/C cg07049167 chr1:166818506 POGK 0.21 4.53 0.38 1.36e-5 Refractive astigmatism; TGCT cis rs1552244 0.832 rs61056817 chr3:10027641 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.43 -6.29 -0.49 4.94e-9 Alzheimer's disease; TGCT cis rs6087990 0.735 rs910083 chr20:31378690 A/C cg13636640 chr20:31349939 DNMT3B 0.98 12.93 0.76 9.81e-25 Ulcerative colitis; TGCT cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg09904177 chr6:26538194 HMGN4 -0.66 -6.27 -0.49 5.38e-9 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg25151919 chr3:44754333 ZNF502 -0.43 -4.94 -0.41 2.43e-6 Depressive symptoms; TGCT cis rs6725041 0.819 rs939224 chr2:213089095 T/C cg16329650 chr2:213403929 ERBB4 -0.53 -4.52 -0.38 1.44e-5 QT interval (ambient particulate matter interaction); TGCT cis rs12497850 0.931 rs7643368 chr3:48992855 T/G cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.98e-6 Parkinson's disease; TGCT cis rs7731657 0.537 rs987024 chr5:130337029 T/G cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs9660992 0.674 rs1151785 chr1:205232299 C/T cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs6988636 1.000 rs61422480 chr8:124188940 C/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs10504229 0.562 rs2014516 chr8:58128288 C/A cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs6076065 0.707 rs12349 chr20:23352480 A/G cg11657817 chr20:23433608 CST11 0.31 5.47 0.44 2.42e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs9905704 0.647 rs2108435 chr17:57102133 T/C cg05425664 chr17:57184151 TRIM37 0.66 5.67 0.45 9.61e-8 Testicular germ cell tumor; TGCT cis rs2996428 0.667 rs17412654 chr1:3758493 T/C cg17848003 chr1:3704513 LRRC47 0.19 5.14 0.42 1.04e-6 Red cell distribution width; TGCT cis rs4665809 1.000 rs6546744 chr2:26302161 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs873946 0.586 rs12774727 chr10:134569910 T/C cg27286337 chr10:134555280 INPP5A 0.39 4.73 0.39 6.02e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6754311 0.773 rs1435576 chr2:136641882 A/T cg07169764 chr2:136633963 MCM6 0.65 5.95 0.47 2.53e-8 Mosquito bite size; TGCT cis rs2836974 0.865 rs34778912 chr21:40667037 T/G cg11644478 chr21:40555479 PSMG1 1.03 11.12 0.71 2.32e-20 Cognitive function; TGCT cis rs10504229 0.861 rs6990617 chr8:58182960 G/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg11062466 chr8:58055876 NA 0.38 4.56 0.38 1.23e-5 Developmental language disorder (linguistic errors); TGCT cis rs259282 0.524 rs731674 chr19:33132395 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.62 5.81 0.46 4.86e-8 Schizophrenia; TGCT cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs739496 0.579 rs16941759 chr12:112367921 A/G cg10833066 chr12:111807467 FAM109A -0.39 -5.45 -0.44 2.61e-7 Platelet count; TGCT cis rs35160687 0.842 rs7593440 chr2:86550657 T/C cg03171300 chr2:86307199 POLR1A -0.27 -4.81 -0.4 4.34e-6 Night sleep phenotypes; TGCT cis rs6831352 0.918 rs4699712 chr4:100060490 A/T cg12011299 chr4:100065546 ADH4 -0.43 -5.07 -0.41 1.38e-6 Alcohol dependence; TGCT cis rs7085104 0.700 rs10883785 chr10:104603588 A/G cg05855489 chr10:104503620 C10orf26 0.54 4.88 0.4 3.15e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs12291225 0.637 rs8570 chr11:14300759 C/G cg19336497 chr11:14380999 RRAS2 -0.38 -5.9 -0.47 3.23e-8 Sense of smell; TGCT cis rs10504229 0.593 rs16921626 chr8:58040359 C/T cg08219700 chr8:58056026 NA 0.29 4.5 0.37 1.54e-5 Developmental language disorder (linguistic errors); TGCT cis rs2301436 0.512 rs6925969 chr6:167501738 C/A cg07741184 chr6:167504864 NA 0.27 5.35 0.43 4.13e-7 Crohn's disease; TGCT cis rs6752107 1.000 rs35300242 chr2:234168790 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.6 0.38 1.04e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT trans rs4719841 0.662 rs9639523 chr7:25991977 A/C cg22329286 chr11:46761054 F2 0.3 6.75 0.52 5.02e-10 Triglyceride levels; TGCT cis rs12048904 0.533 rs1590580 chr1:101292668 A/G cg15686842 chr1:101360669 SLC30A7;EXTL2 0.7 5.67 0.45 9.63e-8 Multiple sclerosis; TGCT cis rs10504229 0.911 rs77203035 chr8:58175458 C/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg11890956 chr21:40555474 PSMG1 1.11 12.39 0.74 1.95e-23 Cognitive function; TGCT cis rs2836974 0.932 rs2150415 chr21:40615367 A/G cg11890956 chr21:40555474 PSMG1 1.06 11.97 0.73 2.05e-22 Cognitive function; TGCT cis rs9322193 0.923 rs35830138 chr6:149989771 T/C cg13206674 chr6:150067644 NUP43 0.53 4.56 0.38 1.23e-5 Lung cancer; TGCT trans rs1496653 0.602 rs71322183 chr3:23438121 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs4273100 0.646 rs2296981 chr17:19213335 C/G cg03910582 chr17:19030146 GRAPL -0.46 -5.09 -0.42 1.31e-6 Schizophrenia; TGCT cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg27454412 chr7:1067447 C7orf50 0.62 4.67 0.39 7.67e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10876993 0.890 rs1689597 chr12:58051886 G/A cg15848620 chr12:58087721 OS9 -0.72 -5.82 -0.46 4.71e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs1971762 0.730 rs12830769 chr12:54087705 G/A cg16917193 chr12:54089295 NA 0.6 4.5 0.37 1.54e-5 Height; TGCT cis rs2276314 1.000 rs4799835 chr18:33571268 G/A cg05985134 chr18:33552581 C18orf21 0.56 4.85 0.4 3.67e-6 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg17554472 chr22:41940697 POLR3H -0.44 -4.47 -0.37 1.75e-5 Vitiligo; TGCT cis rs3796352 1.000 rs11710292 chr3:53117798 T/C cg07884673 chr3:53033167 SFMBT1 0.53 5.23 0.43 6.94e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs57590327 0.679 rs35942842 chr3:81588362 G/A cg07356753 chr3:81810745 GBE1 -0.55 -4.54 -0.38 1.3e-5 Extraversion; TGCT cis rs6815814 1.000 rs11722836 chr4:38811529 T/A cg02016764 chr4:38805732 TLR1 -0.36 -5.71 -0.46 7.91e-8 Breast cancer; TGCT cis rs1008375 0.800 rs35463363 chr4:17613423 G/T cg18681998 chr4:17616180 MED28 0.98 9.34 0.64 5.05e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4478858 0.735 rs6676682 chr1:31809816 C/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs7666738 0.830 rs60994860 chr4:99046753 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.918 rs6002351 chr22:41757223 C/T cg13695892 chr22:41940480 POLR3H -0.85 -8.45 -0.6 6.59e-14 Vitiligo; TGCT cis rs4820539 1.000 rs916584 chr22:23469433 A/G cg21100191 chr22:23484243 RTDR1 0.89 10.51 0.69 7.38e-19 Bone mineral density; TGCT cis rs10504229 0.683 rs7459958 chr8:58111905 G/T cg02725872 chr8:58115012 NA -0.39 -5.15 -0.42 1.01e-6 Developmental language disorder (linguistic errors); TGCT cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg24531977 chr5:56204891 C5orf35 -0.76 -7.66 -0.57 4.53e-12 Initial pursuit acceleration; TGCT cis rs7945705 0.738 rs11042067 chr11:8815453 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.41 -4.57 -0.38 1.16e-5 Hemoglobin concentration; TGCT cis rs2243480 0.614 rs34032527 chr7:65565141 C/G cg07424592 chr7:64974309 NA 1.26 8.11 0.59 4.17e-13 Diabetic kidney disease; TGCT cis rs823143 0.570 rs823082 chr1:205786935 C/T cg23034840 chr1:205782522 SLC41A1 -0.67 -6.6 -0.51 1.07e-9 Monocyte percentage of white cells; TGCT cis rs79349575 0.783 rs4793996 chr17:47019597 T/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg08280861 chr8:58055591 NA 0.36 4.93 0.4 2.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs4499344 0.730 rs380320 chr19:33105904 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.84 8.84 0.62 7.71e-15 Mean platelet volume; TGCT cis rs2271400 1.000 rs2271400 chr8:56791244 C/T cg08417620 chr8:56013556 XKR4 -0.34 -4.49 -0.37 1.61e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Myeloid white cell count;Neutrophil count;Granulocyte count; TGCT cis rs13256369 0.590 rs10113115 chr8:8559588 A/G cg17143192 chr8:8559678 CLDN23 0.49 4.44 0.37 1.97e-5 Obesity-related traits; TGCT cis rs3027009 0.881 rs3026955 chr1:159144034 C/A cg27303699 chr1:158224869 CD1A -0.4 -4.59 -0.38 1.07e-5 Lean body mass and age at menarche (combined); TGCT cis rs6570726 0.967 rs1396648 chr6:145785248 C/A cg23711669 chr6:146136114 FBXO30 -0.68 -6.24 -0.49 6.2e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7698623 1.000 rs4693882 chr4:88752045 G/T cg02735620 chr4:88950514 PKD2 0.4 4.83 0.4 3.96e-6 Cardiovascular disease risk factors; TGCT cis rs644799 0.672 rs11021307 chr11:95501407 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.8 8.99 0.63 3.39e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs797680 0.856 rs4847235 chr1:93627727 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.78 -0.52 4.27e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs6964587 1.000 rs733957 chr7:91707197 C/T cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs28735056 0.565 rs12957336 chr18:77716889 A/G cg20368463 chr18:77673604 PQLC1 -0.46 -5.43 -0.44 2.83e-7 Schizophrenia; TGCT cis rs7246657 0.943 rs10414904 chr19:37830088 G/A cg03233940 chr19:37894644 NA -0.34 -4.53 -0.38 1.34e-5 Coronary artery calcification; TGCT cis rs6424115 0.830 rs2503000 chr1:24197898 C/G cg15997130 chr1:24165203 NA 0.86 9.53 0.65 1.76e-16 Immature fraction of reticulocytes; TGCT cis rs9549260 0.564 rs12184871 chr13:41291928 C/A cg21288729 chr13:41239152 FOXO1 0.93 8.81 0.62 9.38e-15 Red blood cell count; TGCT cis rs586688 1.000 rs1267121 chr1:201644262 C/A cg05779441 chr1:201574716 NA 0.29 4.54 0.38 1.31e-5 Obesity-related traits; TGCT cis rs7949030 0.626 rs1061093 chr11:62334908 G/C cg13298116 chr11:62369859 EML3;MTA2 0.64 9.42 0.65 3.17e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12220898 0.749 rs2377978 chr10:50476193 C/A cg06072769 chr10:50146962 WDFY4 0.36 4.67 0.39 7.64e-6 Inflammatory biomarkers; TGCT cis rs4788570 0.697 rs9635524 chr16:71804956 C/G cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs3892630 0.878 rs7246451 chr19:33209614 C/G cg22980127 chr19:33182716 NUDT19 0.7 5.1 0.42 1.25e-6 Red blood cell traits; TGCT cis rs10032931 0.717 rs970689 chr4:96460537 A/G cg03008707 chr4:96468962 UNC5C -0.35 -4.71 -0.39 6.44e-6 Optic nerve measurement (cup-to-disc ratio); TGCT trans rs17685 0.753 rs1859791 chr7:75786043 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs12693043 0.790 rs2033310 chr2:175409060 A/C cg11778734 chr2:175439522 WIPF1 -0.37 -4.85 -0.4 3.6e-6 Urate levels (BMI interaction); TGCT trans rs2760061 0.819 rs3094913 chr1:228206980 T/C cg16006296 chr10:38738647 LOC399744 -0.31 -7.12 -0.54 7.75e-11 Diastolic blood pressure; TGCT cis rs12510870 0.599 rs7676884 chr4:74449747 C/T cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs7605378 0.964 rs2689763 chr2:200689555 G/A cg23649088 chr2:200775458 C2orf69 0.35 5.83 0.46 4.53e-8 Osteoporosis; TGCT cis rs514406 0.607 rs1930305 chr1:53195481 G/T cg24675658 chr1:53192096 ZYG11B 0.84 10.45 0.68 1.03e-18 Monocyte count; TGCT cis rs8056742 0.558 rs71386881 chr16:85005907 G/T cg00229868 chr16:85520891 NA 0.37 4.64 0.38 8.75e-6 Amyotrophic lateral sclerosis; TGCT cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs4074961 0.565 rs4415526 chr1:38071728 T/C cg17933807 chr1:38061675 GNL2 1.09 16.57 0.83 3.19e-33 Axial length; TGCT cis rs9383153 1.000 rs2237223 chr6:16329741 G/A cg14009473 chr6:15502099 JARID2 0.67 5.16 0.42 9.52e-7 Gambling; TGCT cis rs1901167 0.908 rs14190 chr5:40982977 A/G cg02441090 chr5:41871058 OXCT1 -0.31 -4.61 -0.38 9.86e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7524258 0.868 rs10779678 chr1:7300573 A/G cg07173049 chr1:7289937 CAMTA1 0.29 4.8 0.4 4.42e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs6876348 0.598 rs2526252 chr5:128310259 C/G cg25555059 chr5:128301488 SLC27A6 -0.28 -4.73 -0.39 5.94e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3820068 0.871 rs74539603 chr1:15809601 C/T cg05660106 chr1:15850417 CASP9 1.13 11.01 0.7 4.37e-20 Systolic blood pressure; TGCT cis rs2180341 0.618 rs6683 chr6:127610021 G/A cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs1129187 0.967 rs11752813 chr6:42928017 C/G cg27588902 chr6:42928151 GNMT -0.5 -5.96 -0.47 2.49e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs793571 0.523 rs12439457 chr15:58982390 T/C cg05156742 chr15:59063176 FAM63B 0.49 4.51 0.38 1.45e-5 Schizophrenia; TGCT cis rs3780378 0.875 rs7869668 chr9:5069837 G/A cg02405213 chr9:5042618 JAK2 -0.63 -8.83 -0.62 8.54e-15 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7666738 0.830 rs7679299 chr4:99057620 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7727544 0.606 rs17622208 chr5:131717050 G/A cg24060327 chr5:131705240 SLC22A5 -0.52 -5.57 -0.45 1.52e-7 Blood metabolite levels; TGCT trans rs916888 0.773 rs199534 chr17:44824213 T/G cg22433210 chr17:43662623 NA 1.04 7.37 0.55 2.07e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 0.679 rs16920056 chr8:58106218 C/A cg08280861 chr8:58055591 NA 0.42 4.82 0.4 4.15e-6 Developmental language disorder (linguistic errors); TGCT cis rs7819412 0.538 rs4523214 chr8:10970773 T/A cg27411982 chr8:10470053 RP1L1 -0.24 -5.32 -0.43 4.72e-7 Triglycerides; TGCT cis rs7618915 0.547 rs13069481 chr3:52666866 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs3733631 1.000 rs28650409 chr4:104628577 C/T cg24090629 chr4:104641072 TACR3 -0.73 -5.81 -0.46 4.96e-8 Menarche (age at onset); TGCT cis rs367615 0.704 rs7704824 chr5:108850278 A/G cg17395555 chr5:108820864 NA 0.3 5.75 0.46 6.64e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs12579753 0.956 rs7309624 chr12:82204266 C/A cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs78487399 0.808 rs17030925 chr2:43713808 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.69 0.39 7.06e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4665809 0.590 rs13006973 chr2:26454707 C/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs185694 0.652 rs1296549 chr13:30892055 A/T cg07600127 chr13:30881527 KATNAL1 0.6 5.54 0.45 1.7e-7 Antineutrophil cytoplasmic antibody-associated vasculitis; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg12419862 chr22:24373484 LOC391322 -0.78 -7.5 -0.56 1.05e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs6952808 0.582 rs10479762 chr7:2045351 T/C cg22963979 chr7:1858916 MAD1L1 0.47 7.94 0.58 1.04e-12 Bipolar disorder and schizophrenia; TGCT cis rs360798 0.512 rs2710637 chr2:63173450 G/A cg17519650 chr2:63277830 OTX1 0.63 5.77 0.46 6.01e-8 Coronary artery disease; TGCT cis rs8078723 0.677 rs11658328 chr17:38149236 T/C cg17467752 chr17:38218738 THRA -0.53 -5.37 -0.43 3.8e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs13191362 0.507 rs2023015 chr6:163060528 A/T cg21926612 chr6:163149169 PACRG;PARK2 -0.6 -5.48 -0.44 2.25e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs1814175 0.645 rs1818895 chr11:50031523 G/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs11190604 1.000 rs10883501 chr10:102238326 A/G cg23241863 chr10:102295624 HIF1AN 0.63 4.95 0.41 2.41e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9486719 1.000 rs12193732 chr6:96942609 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT trans rs7618501 1.000 rs695238 chr3:49869158 A/C cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs7172809 0.524 rs4886852 chr15:77417173 A/T cg22256960 chr15:77711686 NA -0.47 -4.46 -0.37 1.83e-5 Glucose homeostasis traits; TGCT cis rs916888 0.773 rs199447 chr17:44812188 C/T cg17911788 chr17:44343683 NA -0.67 -7.15 -0.54 6.59e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11098499 0.588 rs6534149 chr4:120559292 T/G cg09307838 chr4:120376055 NA -0.58 -5.38 -0.43 3.62e-7 Corneal astigmatism; TGCT cis rs4803468 0.904 rs60781668 chr19:41944842 A/T cg09537434 chr19:41945824 ATP5SL 0.91 10.21 0.68 3.82e-18 Height; TGCT cis rs9322193 0.923 rs4455682 chr6:150021297 C/T cg13206674 chr6:150067644 NUP43 0.52 4.54 0.38 1.32e-5 Lung cancer; TGCT cis rs6424115 0.708 rs13551 chr1:24180962 T/C cg15997130 chr1:24165203 NA -0.7 -7.02 -0.53 1.26e-10 Immature fraction of reticulocytes; TGCT cis rs72945132 0.882 rs67244582 chr11:70122009 G/A cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9486719 1.000 rs12212614 chr6:97036466 T/G cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs5750830 0.594 rs1010169 chr22:39778167 C/T cg24399712 chr22:39784796 NA 0.95 11.16 0.71 1.93e-20 Intelligence (multi-trait analysis); TGCT cis rs1800469 1.000 rs1549933 chr19:41871142 A/G cg09537434 chr19:41945824 ATP5SL -0.58 -5.26 -0.43 6.17e-7 Colorectal cancer; TGCT cis rs514406 0.505 rs6688064 chr1:53165609 C/T cg22166914 chr1:53195759 ZYG11B 0.44 7.66 0.57 4.64e-12 Monocyte count; TGCT cis rs1208285 0.964 rs9389106 chr6:134150456 C/T cg01805282 chr6:133563764 EYA4 0.4 4.44 0.37 2e-5 Infantile hypertrophic pyloric stenosis; TGCT cis rs231513 0.638 rs79139991 chr17:42010359 C/T cg26893861 chr17:41843967 DUSP3 0.82 5.03 0.41 1.67e-6 Cognitive function; TGCT cis rs9549367 0.737 rs71446680 chr13:113894846 C/T cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs34172651 0.517 rs189919 chr16:24737741 G/A cg06028605 chr16:24865363 SLC5A11 -0.42 -4.53 -0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.735 rs778595 chr5:140036681 G/A cg19875535 chr5:140030758 IK -0.37 -6.25 -0.49 6.12e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs7175404 0.591 rs75029049 chr15:94061120 C/T cg18324227 chr15:93584571 NA 0.49 4.56 0.38 1.2e-5 Attention deficit hyperactivity disorder; TGCT cis rs7528684 0.768 rs6675393 chr1:157734907 C/T cg17134153 chr1:157670328 FCRL3 -0.28 -4.95 -0.41 2.37e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs13242816 1.000 rs12706090 chr7:116104045 A/G cg02799643 chr7:116139180 CAV2 0.45 5.37 0.43 3.77e-7 P wave duration; TGCT cis rs9926296 0.605 rs12709094 chr16:89853017 A/G cg26513180 chr16:89883248 FANCA 1.07 14.96 0.8 1.48e-29 Vitiligo; TGCT cis rs1857353 1.000 rs80337562 chr1:75878243 A/T cg11838876 chr1:75668600 SLC44A5 -0.47 -4.56 -0.38 1.2e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs4786125 0.636 rs8062299 chr16:6902722 T/C cg03623568 chr16:6915990 A2BP1 -0.42 -6.12 -0.48 1.13e-8 Heart rate variability traits (SDNN); TGCT cis rs798554 0.721 rs2527680 chr7:2892361 C/T cg13628971 chr7:2884303 GNA12 0.58 4.61 0.38 1e-5 Height; TGCT cis rs6987853 0.966 rs1947297 chr8:42453023 A/G cg20539142 chr8:42623718 CHRNA6 -0.2 -5.0 -0.41 1.95e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg22764044 chr5:178986830 RUFY1 -0.49 -5.61 -0.45 1.23e-7 Lung cancer; TGCT cis rs7044106 0.762 rs1547267 chr9:123408736 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.75 0.39 5.55e-6 Hip circumference adjusted for BMI; TGCT cis rs7552404 0.627 rs12127049 chr1:76353248 G/A cg10523679 chr1:76189770 ACADM 0.84 7.63 0.57 5.26e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg10150615 chr22:24372951 LOC391322 -1.01 -13.12 -0.76 3.43e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2677744 0.534 rs6496739 chr15:91494430 C/T cg22570213 chr15:91497863 RCCD1 0.42 5.08 0.41 1.37e-6 Attention deficit hyperactivity disorder; TGCT cis rs6426558 0.537 rs2813969 chr1:227404082 T/C cg10327440 chr1:227177885 CDC42BPA 0.59 6.81 0.52 3.72e-10 Neutrophil percentage of white cells; TGCT cis rs6089829 0.962 rs6062780 chr20:61666648 T/C cg03213289 chr20:61660250 NA 0.68 9.99 0.67 1.36e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs75686122 0.655 rs74969771 chr8:104636083 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs7260538 0.509 rs10420194 chr19:41529781 A/T cg27089200 chr19:41531976 NA 0.52 6.7 0.52 6.45e-10 DDT metabolite (p,p'-DDE levels); TGCT cis rs2982552 0.873 rs3020308 chr6:152068685 A/G cg22157087 chr6:152012887 ESR1 0.2 4.77 0.39 5e-6 Bone properties (heel); TGCT cis rs1775715 0.737 rs2799012 chr10:32103077 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.38e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2067615 0.524 rs10778499 chr12:107068387 C/T cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs6831352 0.918 rs13112733 chr4:100050319 A/T cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs4925325 0.955 rs1776262 chr20:60516023 G/T cg06108461 chr20:60628389 TAF4 0.39 4.8 0.4 4.51e-6 Obesity-related traits; TGCT cis rs1552244 0.882 rs3846168 chr3:9996925 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -7.0 -0.53 1.4e-10 Alzheimer's disease; TGCT cis rs3806843 1.000 rs10066278 chr5:140156318 A/C cg19875535 chr5:140030758 IK 0.37 6.23 0.49 6.53e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs6815814 0.950 rs56357984 chr4:38806462 G/A cg02016764 chr4:38805732 TLR1 -0.34 -5.27 -0.43 5.82e-7 Breast cancer; TGCT cis rs1801251 1.000 rs2674839 chr2:233669040 G/C cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs2228479 0.850 rs11644804 chr16:89976224 G/A cg06558623 chr16:89946397 TCF25 0.56 6.55 0.51 1.4e-9 Skin colour saturation; TGCT cis rs6728642 0.808 rs113319086 chr2:97633267 G/C cg26665480 chr2:98280029 ACTR1B -0.96 -5.36 -0.43 3.91e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs7027203 0.828 rs10761287 chr9:96609150 A/G cg14598338 chr9:96623480 NA -0.61 -9.54 -0.65 1.68e-16 DNA methylation (variation); TGCT cis rs593982 0.688 rs55971008 chr11:65395860 G/A cg08755490 chr11:65554678 OVOL1 -1.06 -5.22 -0.42 7.44e-7 Atopic dermatitis; TGCT trans rs3780486 0.757 rs10121987 chr9:33119818 A/G cg04842962 chr6:43655489 MRPS18A 1.23 15.13 0.81 6e-30 IgG glycosylation; TGCT cis rs6671200 0.790 rs259357 chr1:95711478 G/T cg26537280 chr1:95699037 RWDD3 -0.7 -5.55 -0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs1061377 1.000 rs7655122 chr4:39122016 A/G cg24403649 chr4:39172243 NA 0.18 4.44 0.37 1.99e-5 Uric acid levels; TGCT cis rs9467773 0.583 rs2498380 chr6:26643996 C/G cg02458000 chr6:26745757 NA -0.55 -5.3 -0.43 5.12e-7 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs6938071 chr6:8464845 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.42e-8 Motion sickness; TGCT cis rs7208859 0.623 rs426434 chr17:28925353 C/T cg04154034 chr17:28927549 LRRC37B2 0.86 4.95 0.41 2.35e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs265548 0.646 rs36692 chr19:17906839 C/T cg03316864 chr19:17906309 B3GNT3 0.44 5.24 0.43 6.81e-7 Tumor biomarkers; TGCT cis rs1472147 1.000 rs4323418 chr7:128506970 C/T cg05395852 chr7:128750384 NA -0.17 -5.45 -0.44 2.62e-7 Calcium levels; TGCT trans rs8073060 0.586 rs2523114 chr17:34023762 G/A cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs910187 0.678 rs8115769 chr20:45813704 A/C cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs10927875 0.550 rs12121918 chr1:16183556 C/A cg21385522 chr1:16154831 NA -0.91 -9.29 -0.64 6.69e-16 Dilated cardiomyopathy; TGCT cis rs4851266 0.898 rs12614880 chr2:100849341 A/G cg07810366 chr2:100720526 AFF3 -0.34 -4.6 -0.38 1.05e-5 Educational attainment; TGCT cis rs1799949 1.000 rs11657053 chr17:41191129 G/T cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs1903068 0.657 rs2239702 chr4:55992139 C/T cg09978860 chr4:56023921 NA 0.52 5.29 0.43 5.46e-7 Endometriosis; TGCT cis rs1552244 0.810 rs6809572 chr3:10100145 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs12908161 0.959 rs61074241 chr15:85333396 C/T cg11189052 chr15:85197271 WDR73 0.71 5.83 0.46 4.42e-8 Schizophrenia; TGCT cis rs12210905 1.000 rs12209456 chr6:27085225 C/T cg08851530 chr6:28072375 NA 1.21 5.58 0.45 1.43e-7 Hip circumference adjusted for BMI; TGCT cis rs7267979 1.000 rs6115191 chr20:25440478 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs13394619 0.775 rs10165819 chr2:11722102 A/T cg07314298 chr2:11723111 GREB1 -0.29 -4.98 -0.41 2.09e-6 Endometriosis; TGCT cis rs9814567 0.752 rs4318591 chr3:134328333 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs875971 1.000 rs1544549 chr7:66090663 T/A cg18876405 chr7:65276391 NA -0.33 -5.05 -0.41 1.52e-6 Aortic root size; TGCT cis rs17122693 0.551 rs2934683 chr14:51058511 C/T cg04730355 chr14:51134070 SAV1 1.19 12.02 0.73 1.56e-22 Cognitive performance; TGCT cis rs17152411 1.000 rs12569940 chr10:126592684 T/C cg07906193 chr10:126599966 NA 0.42 5.16 0.42 9.36e-7 Height; TGCT cis rs9517320 1.000 rs7994160 chr13:99132749 C/A cg07423050 chr13:99094983 FARP1 0.23 4.58 0.38 1.11e-5 Longevity; TGCT cis rs7267979 0.933 rs2261109 chr20:25259200 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28595532 0.920 rs56303276 chr4:119723514 C/T cg14228332 chr4:119757509 SEC24D 1.38 6.91 0.53 2.21e-10 Cannabis dependence symptom count; TGCT cis rs7208859 0.524 rs57670615 chr17:29069498 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs981844 0.601 rs1337 chr4:154631587 C/G cg14289246 chr4:154710475 SFRP2 1.05 8.41 0.6 8.3e-14 Response to statins (LDL cholesterol change); TGCT cis rs7666738 0.830 rs11725095 chr4:99009711 T/A cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6912958 0.781 rs7742965 chr6:88278196 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs854765 0.663 rs12941550 chr17:17753828 C/A cg09796270 chr17:17721594 SREBF1 -0.26 -4.88 -0.4 3.13e-6 Total body bone mineral density; TGCT cis rs7681440 0.874 rs1442154 chr4:90775761 C/G cg14346243 chr4:90757452 SNCA -0.56 -5.47 -0.44 2.41e-7 Dementia with Lewy bodies; TGCT cis rs2014572 0.967 rs10418480 chr19:57755055 C/T cg24459738 chr19:57751996 ZNF805 -0.54 -5.4 -0.44 3.21e-7 Hyperactive-impulsive symptoms; TGCT trans rs7819412 0.668 rs2409694 chr8:10946861 T/G cg15556689 chr8:8085844 FLJ10661 -0.78 -6.86 -0.52 2.91e-10 Triglycerides; TGCT cis rs3091242 0.933 rs35530120 chr1:25785451 A/G cg10117171 chr1:25599238 RHD 0.3 4.79 0.39 4.76e-6 Erythrocyte sedimentation rate; TGCT trans rs10506458 0.834 rs17738403 chr12:63389200 A/G cg22491629 chr6:157744540 C6orf35 -0.99 -8.5 -0.61 5.08e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.1 0.54 8.35e-11 Prudent dietary pattern; TGCT cis rs208515 0.525 rs10944863 chr6:66676238 C/T cg07460842 chr6:66804631 NA 0.87 9.16 0.64 1.32e-15 Exhaled nitric oxide levels; TGCT cis rs4073582 0.595 rs801737 chr11:65928193 T/C cg16950941 chr11:66035639 RAB1B 0.55 5.42 0.44 2.94e-7 Gout; TGCT cis rs62244186 0.659 rs9855433 chr3:44468065 C/A cg04389838 chr3:44770851 ZNF501 -0.41 -5.47 -0.44 2.33e-7 Depressive symptoms; TGCT trans rs1974653 0.672 rs75967927 chr22:20068496 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs8026198 0.568 rs58712247 chr15:42616288 C/CA cg20584732 chr15:42349694 NA 0.45 4.53 0.38 1.39e-5 Fibrinogen levels; TGCT cis rs6964587 1.000 rs10270598 chr7:91700827 T/C cg17063962 chr7:91808500 NA 0.88 9.65 0.66 8.73e-17 Breast cancer; TGCT cis rs76419734 1.000 rs11726094 chr4:106773387 G/T cg24545054 chr4:106630052 GSTCD;INTS12 1.09 4.45 0.37 1.9e-5 Post bronchodilator FEV1; TGCT cis rs941408 1.000 rs941406 chr19:2803623 A/G cg06609049 chr19:2785107 THOP1 0.85 7.34 0.55 2.49e-11 Total cholesterol levels; TGCT cis rs3099143 1.000 rs1114717 chr15:77086078 A/G cg21673338 chr15:77095150 SCAPER 0.51 5.12 0.42 1.11e-6 Recalcitrant atopic dermatitis; TGCT cis rs992157 0.835 rs13005100 chr2:219151767 C/T cg00012203 chr2:219082015 ARPC2 -0.8 -7.98 -0.58 8.26e-13 Colorectal cancer; TGCT trans rs1005277 0.579 rs2505237 chr10:38438898 T/G cg27523141 chr10:43048294 ZNF37B 0.74 8.61 0.61 2.7e-14 Extrinsic epigenetic age acceleration; TGCT cis rs7681440 0.874 rs1442151 chr4:90775491 T/A cg26578617 chr4:90757533 SNCA -0.44 -4.54 -0.38 1.31e-5 Dementia with Lewy bodies; TGCT cis rs2836974 0.897 rs2836925 chr21:40532353 T/C cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs7937682 0.710 rs674230 chr11:111437887 A/G cg09085632 chr11:111637200 PPP2R1B -0.98 -10.12 -0.67 6.37e-18 Primary sclerosing cholangitis; TGCT cis rs35306767 0.903 rs12769002 chr10:927666 C/G cg26597838 chr10:835615 NA -0.85 -12.57 -0.75 7.33e-24 Eosinophil percentage of granulocytes; TGCT cis rs35146811 0.735 rs2272345 chr7:99797031 C/G cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs7552404 0.731 rs11588578 chr1:76400539 T/G cg03433033 chr1:76189801 ACADM 0.75 7.14 0.54 6.77e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs13191362 1.000 rs35092540 chr6:163090778 A/G cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.05 0.59 5.69e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9916302 0.605 rs2879258 chr17:37399379 G/T cg07936489 chr17:37558343 FBXL20 -0.86 -6.14 -0.48 1.02e-8 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs6854902 chr4:99033416 T/G cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs62318503 chr4:98935479 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs919433 0.680 rs2605039 chr2:198362851 C/A cg00792783 chr2:198669748 PLCL1 0.52 4.77 0.39 4.99e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs9443645 0.901 rs55755815 chr6:79607121 G/T cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7584330 0.666 rs72620816 chr2:238353604 C/T cg14458575 chr2:238380390 NA 0.55 8.09 0.59 4.56e-13 Prostate cancer; TGCT cis rs12497850 0.931 rs6791542 chr3:48787219 A/G cg18654377 chr3:49208889 KLHDC8B -0.41 -5.49 -0.44 2.15e-7 Parkinson's disease; TGCT cis rs80282103 0.764 rs12247779 chr10:1107957 T/G cg08668510 chr10:1095578 IDI1 1.07 5.3 0.43 5.01e-7 Glomerular filtration rate (creatinine); TGCT cis rs4654899 0.802 rs6685306 chr1:21219050 C/T cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs2836950 0.545 rs2297256 chr21:40558421 C/T cg17971929 chr21:40555470 PSMG1 -0.5 -4.55 -0.38 1.25e-5 Menarche (age at onset); TGCT cis rs11098499 0.954 rs13133522 chr4:120324424 A/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs6951245 0.744 rs10275401 chr7:1213943 A/C cg09177884 chr7:1199841 ZFAND2A -0.73 -4.58 -0.38 1.11e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12142240 0.698 rs17357676 chr1:46812444 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.84 0.46 4.33e-8 Menopause (age at onset); TGCT cis rs1862618 0.802 rs986049 chr5:56110233 G/A cg24531977 chr5:56204891 C5orf35 -0.76 -7.66 -0.57 4.53e-12 Initial pursuit acceleration; TGCT trans rs561341 1.000 rs72823787 chr17:30283809 A/T cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs10871290 1.000 rs10871290 chr16:74472696 C/T cg01733217 chr16:74700730 RFWD3 -0.52 -4.77 -0.39 5.01e-6 Breast cancer; TGCT trans rs77457752 0.690 rs17224436 chr9:13912875 C/T cg12973904 chr7:149457885 NA -0.5 -7.47 -0.56 1.24e-11 Breast cancer; TGCT cis rs77972916 0.517 rs17406126 chr2:43546632 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -4.69 -0.39 7.07e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs2115630 0.818 rs7176522 chr15:85215383 C/G cg12501888 chr15:85177176 SCAND2 -0.47 -4.44 -0.37 1.96e-5 P wave terminal force; TGCT cis rs13108904 0.935 rs4974575 chr4:1252028 A/G cg13395646 chr4:1353034 KIAA1530 -0.39 -5.19 -0.42 8.46e-7 Obesity-related traits; TGCT cis rs9611565 0.729 rs505533 chr22:41864216 A/C cg17554472 chr22:41940697 POLR3H 0.46 5.0 0.41 1.89e-6 Vitiligo; TGCT cis rs1799949 1.000 rs12950607 chr17:41299928 G/C cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs7772486 0.655 rs2142981 chr6:146071695 G/C cg23711669 chr6:146136114 FBXO30 -0.97 -11.03 -0.7 4.03e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.515 rs111560858 chr3:10166845 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg17554472 chr22:41940697 POLR3H -0.42 -4.7 -0.39 6.85e-6 Vitiligo; TGCT cis rs3806843 0.735 rs801188 chr5:140066916 G/T cg19875535 chr5:140030758 IK -0.37 -6.25 -0.49 6.12e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs651907 0.557 rs36002990 chr3:101437862 G/A cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.78 -0.52 4.35e-10 Colorectal cancer; TGCT cis rs3617 0.625 rs11719137 chr3:52876389 G/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2019137 0.936 rs3828189 chr2:113954496 T/A cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs67311347 1.000 rs12633431 chr3:40505740 C/T cg17264618 chr3:40429014 ENTPD3 -0.32 -4.64 -0.38 8.57e-6 Renal cell carcinoma; TGCT cis rs79349575 0.783 rs62078372 chr17:47028989 T/C cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs66573146 1.000 rs66712119 chr4:6965428 A/T cg01220768 chr4:7056774 TADA2B 0.35 4.63 0.38 8.96e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7267979 1.000 rs6083804 chr20:25317060 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4819052 0.851 rs7275468 chr21:46656499 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 6.32 0.49 4.3e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9611565 0.879 rs5758307 chr22:41750219 A/G cg02107564 chr22:41488750 EP300 -0.56 -4.54 -0.38 1.29e-5 Vitiligo; TGCT cis rs727563 0.635 rs5758444 chr22:42133921 T/A cg06634786 chr22:41940651 POLR3H 0.87 8.12 0.59 3.86e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg05738196 chr6:26577821 NA 0.86 10.49 0.69 8.31e-19 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.507 rs199741 chr6:25931577 A/G cg03517284 chr6:25882590 NA -0.94 -9.09 -0.63 1.98e-15 Intelligence (multi-trait analysis); TGCT cis rs546131 0.642 rs508062 chr11:34843820 C/G cg06937548 chr11:34938143 PDHX;APIP 0.54 4.75 0.39 5.54e-6 Lung disease severity in cystic fibrosis; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg09033563 chr22:24373618 LOC391322 -0.48 -4.71 -0.39 6.57e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12908161 1.000 rs62019469 chr15:85321220 T/C cg12863693 chr15:85201151 NMB 0.43 5.12 0.42 1.15e-6 Schizophrenia; TGCT cis rs7072216 0.763 rs2147901 chr10:100165496 A/C cg26618903 chr10:100175079 PYROXD2 0.4 4.51 0.38 1.49e-5 Metabolite levels; TGCT cis rs1153858 0.832 rs1145078 chr15:45682277 C/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.68 0.45 9.02e-8 Homoarginine levels; TGCT cis rs13191362 1.000 rs35575481 chr6:163007746 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2806561 0.704 rs6680974 chr1:23376233 A/G cg12483005 chr1:23474871 LUZP1 0.38 4.76 0.39 5.34e-6 Height; TGCT cis rs11172134 0.508 rs1800181 chr12:57578288 C/T cg19258868 chr12:57585184 LRP1 -0.32 -6.09 -0.48 1.32e-8 Urate levels in overweight individuals; TGCT cis rs7584330 0.554 rs7587496 chr2:238387632 A/G cg14458575 chr2:238380390 NA 0.58 5.05 0.41 1.53e-6 Prostate cancer; TGCT cis rs9467773 0.587 rs3208733 chr6:26414425 C/T cg15659132 chr6:26577336 NA -0.43 -4.52 -0.38 1.45e-5 Intelligence (multi-trait analysis); TGCT cis rs10782582 0.609 rs1630302 chr1:76412090 A/T cg10523679 chr1:76189770 ACADM -0.57 -5.14 -0.42 1.04e-6 Daytime sleep phenotypes; TGCT cis rs10751667 0.666 rs7395402 chr11:950293 A/G cg06064525 chr11:970664 AP2A2 0.34 7.82 0.57 2.02e-12 Alzheimer's disease (late onset); TGCT cis rs644799 0.623 rs17207890 chr11:95490754 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.75 7.47 0.56 1.27e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs17376456 0.825 rs10056879 chr5:93282218 C/A cg25358565 chr5:93447407 FAM172A 1.01 6.35 0.5 3.72e-9 Diabetic retinopathy; TGCT cis rs6570726 0.846 rs870491 chr6:145933390 T/G cg05347473 chr6:146136440 FBXO30 0.5 4.61 0.38 9.8200000000000008e-06 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.659 rs4822036 chr22:41936019 A/G cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs2440129 0.632 rs13396 chr17:6905624 T/C cg19536664 chr17:6899085 ALOX12 0.39 6.1 0.48 1.23e-8 Tonsillectomy; TGCT trans rs2688608 0.592 rs2306328 chr10:75579510 C/T cg13918328 chr10:52500089 ASAH2B 0.7 7.07 0.54 9.81e-11 Inflammatory bowel disease; TGCT cis rs4972806 0.849 rs2071581 chr2:177026148 G/T cg13092806 chr2:177043255 NA 0.56 4.85 0.4 3.6e-6 IgG glycosylation; TGCT trans rs916888 0.773 rs199451 chr17:44801784 G/A cg22433210 chr17:43662623 NA 1.04 7.25 0.55 3.96e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2692947 0.673 rs2692894 chr2:96784934 T/G cg23100626 chr2:96804247 ASTL -0.44 -5.21 -0.42 7.78e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7267979 0.932 rs2387891 chr20:25470328 C/G cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 1.000 rs10946835 chr6:26533757 C/T cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs7412746 0.658 rs6658066 chr1:150918937 T/G cg09365446 chr1:150670422 GOLPH3L 0.34 4.71 0.39 6.58e-6 Melanoma; TGCT cis rs9318086 0.712 rs12875437 chr13:24453956 A/G cg25267304 chr13:24462978 PCOTH;MIPEP 0.77 8.25 0.6 1.99e-13 Myopia (pathological); TGCT cis rs10484885 0.824 rs72921954 chr6:90586656 A/G cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.11e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7954584 0.635 rs7309024 chr12:122338334 C/T cg13699009 chr12:122356056 WDR66 0.29 6.56 0.51 1.32e-9 Mean corpuscular volume; TGCT cis rs28386778 0.799 rs2665836 chr17:61898135 C/A cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.04 0.53 1.16e-10 Prudent dietary pattern; TGCT cis rs9486719 1.000 rs12197411 chr6:97039621 G/A cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs16866061 0.515 rs1027340 chr2:225370554 C/A cg12698349 chr2:225449008 CUL3 1.12 15.51 0.81 8.08e-31 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs28595532 0.920 rs115500312 chr4:119752551 G/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs11249608 0.548 rs11951738 chr5:178491228 G/A cg21905437 chr5:178450457 ZNF879 0.45 4.64 0.38 8.87e-6 Pubertal anthropometrics; TGCT cis rs1552244 1.000 rs9881859 chr3:10072814 A/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 6.06 0.48 1.52e-8 Alzheimer's disease; TGCT cis rs7666738 0.830 rs7664051 chr4:98766970 C/G cg18180107 chr4:99064573 C4orf37 0.53 5.07 0.41 1.38e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6912958 0.559 rs446851 chr6:88043640 G/A cg04972856 chr6:88032051 C6orf162;GJB7 0.4 4.7 0.39 6.83e-6 Monocyte percentage of white cells; TGCT cis rs1218582 0.711 rs4845677 chr1:154838050 C/T cg24250549 chr1:154909240 PMVK 0.55 5.18 0.42 8.74e-7 Prostate cancer; TGCT cis rs6089829 0.962 rs6062393 chr20:61663230 G/A cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs9811920 0.809 rs4928150 chr3:99685991 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 -0.44 -4.83 -0.4 3.88e-6 Axial length; TGCT cis rs7208859 0.673 rs73263981 chr17:28920502 A/G cg19761014 chr17:28927070 LRRC37B2 0.56 4.81 0.4 4.32e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11190604 0.767 rs10883478 chr10:102162852 C/T cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7829975 0.774 rs13259216 chr8:8673601 A/C cg06636001 chr8:8085503 FLJ10661 0.65 5.8 0.46 5.26e-8 Mood instability; TGCT cis rs904251 0.523 rs1757191 chr6:37482871 C/T cg25019722 chr6:37503610 NA -0.52 -7.9 -0.58 1.28e-12 Cognitive performance; TGCT cis rs1011108 1.000 rs1011108 chr2:26782621 A/G cg18742855 chr2:26800399 C2orf70 -0.26 -5.77 -0.46 6.07e-8 Periodontal microbiota; TGCT cis rs7621025 0.500 rs12629000 chr3:136643571 T/A cg15507776 chr3:136538369 TMEM22 0.67 6.26 0.49 5.69e-9 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs9486719 0.843 rs3860230 chr6:97036560 T/A cg06623918 chr6:96969491 KIAA0776 -1.03 -10.2 -0.68 4.18e-18 Migraine;Coronary artery disease; TGCT cis rs7017914 0.905 rs3110249 chr8:71935545 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.03 -0.41 1.68e-6 Bone mineral density; TGCT cis rs16958440 0.867 rs117060920 chr18:44709035 G/A cg17192377 chr18:44677553 HDHD2 0.65 4.64 0.38 8.62e-6 Sitting height ratio; TGCT cis rs60154123 0.505 rs7540237 chr1:210053325 C/T cg22029157 chr1:209979665 IRF6 0.76 5.52 0.44 1.89e-7 Coronary artery disease; TGCT cis rs1124376 0.688 rs11715447 chr3:20140129 A/C cg05072819 chr3:20081367 KAT2B 0.81 5.51 0.44 2.02e-7 Bipolar disorder and schizophrenia; TGCT cis rs7103648 0.669 rs7131262 chr11:47836302 T/A cg20307385 chr11:47447363 PSMC3 0.77 7.37 0.55 2.1e-11 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs910316 0.967 rs4903293 chr14:75656568 A/G cg08847533 chr14:75593920 NEK9 -0.91 -9.71 -0.66 6.33e-17 Height; TGCT trans rs9859260 0.710 rs366268 chr3:195782177 A/G cg17074656 chr11:63784126 MACROD1 0.52 6.67 0.51 7.49e-10 Mean corpuscular volume; TGCT cis rs12477438 0.798 rs9308816 chr2:99637230 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.68 -5.84 -0.46 4.27e-8 Chronic sinus infection; TGCT cis rs992157 0.764 rs62183964 chr2:219186592 G/A cg00012203 chr2:219082015 ARPC2 0.7 6.58 0.51 1.16e-9 Colorectal cancer; TGCT cis rs1334894 1.000 rs2294807 chr6:35555110 C/T cg24281267 chr6:35479648 TULP1 -0.43 -4.47 -0.37 1.78e-5 Coronary artery disease; TGCT cis rs7914558 0.932 rs4307650 chr10:104959852 C/A cg05855489 chr10:104503620 C10orf26 0.52 4.59 0.38 1.06e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10744422 0.562 rs10847775 chr12:123298221 G/A cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs9303401 0.661 rs9902820 chr17:56637545 A/C cg12560992 chr17:57184187 TRIM37 0.6 6.5 0.5 1.74e-9 Cognitive test performance; TGCT cis rs12220898 0.679 rs4582889 chr10:50475014 A/C cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.85e-5 Inflammatory biomarkers; TGCT cis rs11578119 0.806 rs12409985 chr1:170377564 G/A cg09767346 chr1:170501363 GORAB 0.72 5.78 0.46 5.76e-8 Male-pattern baldness; TGCT cis rs10791097 0.739 rs4936120 chr11:130723452 G/A cg05962950 chr11:130786565 SNX19 0.83 9.85 0.66 2.99e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs908922 0.651 rs4240886 chr1:152530396 A/T cg20991723 chr1:152506922 NA -0.45 -6.05 -0.48 1.6e-8 Hair morphology; TGCT trans rs9951602 0.512 rs9304070 chr18:76654890 A/C cg02800362 chr5:177631904 HNRNPAB 1.1 12.7 0.75 3.48e-24 Obesity-related traits; TGCT cis rs11249608 0.548 rs17078988 chr5:178459283 A/G cg23951258 chr5:178450506 ZNF879 0.43 4.53 0.38 1.37e-5 Pubertal anthropometrics; TGCT cis rs1799949 1.000 rs12516 chr17:41196408 G/A cg23758822 chr17:41437982 NA 0.73 6.74 0.52 5.43e-10 Menopause (age at onset); TGCT cis rs9486719 0.948 rs11152952 chr6:96894303 A/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs13108904 0.967 rs900027 chr4:1279360 G/A cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs208520 0.690 rs6932475 chr6:66863155 G/A cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs9814567 1.000 rs4368544 chr3:134300014 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs138229 0.506 rs138233 chr22:50559953 G/A cg08875078 chr22:50639485 SELO 0.56 4.59 0.38 1.07e-5 Behavioural disinhibition (generation interaction); TGCT cis rs2224391 0.590 rs72813693 chr6:5273464 T/C cg09085698 chr6:5261316 LYRM4;FARS2 -1.0 -5.18 -0.42 8.9e-7 Height; TGCT cis rs10504229 0.679 rs7840100 chr8:58036662 T/G cg08280861 chr8:58055591 NA 0.35 4.98 0.41 2.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs62064224 0.791 rs2344977 chr17:30720573 C/G cg18200150 chr17:30822561 MYO1D 0.62 8.41 0.6 8.08e-14 Schizophrenia; TGCT cis rs10504229 0.815 rs75577263 chr8:58188434 A/G cg08280861 chr8:58055591 NA 0.36 4.98 0.41 2.1e-6 Developmental language disorder (linguistic errors); TGCT cis rs7474896 0.583 rs10827817 chr10:37997974 A/G cg13720705 chr10:37990370 NA 0.31 4.72 0.39 6.33e-6 Obesity (extreme); TGCT cis rs9527 0.590 rs12246739 chr10:104787019 A/C cg15744005 chr10:104629667 AS3MT 0.47 5.35 0.43 4.16e-7 Arsenic metabolism; TGCT cis rs9916302 0.904 rs8077104 chr17:37530510 A/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs11677370 0.603 rs10198219 chr2:3854600 T/C cg17052675 chr2:3827356 NA -0.43 -6.92 -0.53 2.15e-10 Type 2 diabetes; TGCT cis rs4819052 0.807 rs4819047 chr21:46665139 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.74 6.73 0.52 5.61e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7954584 0.635 rs3847694 chr12:122325820 A/G cg10207240 chr12:122356781 WDR66 0.34 4.65 0.39 8.21e-6 Mean corpuscular volume; TGCT cis rs7666738 0.830 rs13138059 chr4:99050430 A/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs62380364 0.870 rs4145738 chr5:88150289 G/A cg22951263 chr5:87985283 NA -0.48 -4.62 -0.38 9.39e-6 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.904 rs7503069 chr17:37697128 C/G cg15445000 chr17:37608096 MED1 0.31 4.5 0.37 1.53e-5 Glomerular filtration rate (creatinine); TGCT cis rs2120019 0.938 rs8033925 chr15:75311959 A/G cg17294928 chr15:75287854 SCAMP5 -0.79 -6.27 -0.49 5.46e-9 Blood trace element (Zn levels); TGCT cis rs9467773 1.000 rs1535277 chr6:26567802 G/T cg26531700 chr6:26746687 NA 0.5 4.85 0.4 3.64e-6 Intelligence (multi-trait analysis); TGCT cis rs1971762 0.762 rs7312853 chr12:54073597 C/G cg16917193 chr12:54089295 NA -0.6 -4.85 -0.4 3.7e-6 Height; TGCT cis rs9393692 1.000 rs3999544 chr6:26285867 C/T cg00631329 chr6:26305371 NA -0.46 -6.82 -0.52 3.51e-10 Educational attainment; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg26354017 chr1:205819088 PM20D1 0.67 9.29 0.64 6.74e-16 Menarche (age at onset); TGCT cis rs6076065 0.748 rs6137933 chr20:23383103 A/T cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs9810089 0.900 rs11915629 chr3:136139730 C/G cg12473912 chr3:136751656 NA 0.35 5.1 0.42 1.22e-6 Gestational age at birth (child effect); TGCT cis rs2204008 0.837 rs11180821 chr12:38242843 A/G cg26384229 chr12:38710491 ALG10B 0.84 7.28 0.55 3.29e-11 Bladder cancer; TGCT cis rs3806843 1.000 rs6891995 chr5:140172008 A/G cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs11671005 0.735 rs11668789 chr19:58928309 C/T cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT cis rs4319547 0.661 rs7398014 chr12:122943980 T/C cg23029597 chr12:123009494 RSRC2 -0.28 -4.52 -0.38 1.41e-5 Body mass index; TGCT cis rs877282 0.891 rs34652870 chr10:772218 T/C cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg03264133 chr6:25882463 NA -0.6 -5.61 -0.45 1.23e-7 Intelligence (multi-trait analysis); TGCT cis rs66573146 1.000 rs28384174 chr4:6961107 G/T cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs6088590 1.000 rs6119524 chr20:33373813 C/T cg06115741 chr20:33292138 TP53INP2 0.66 5.51 0.44 2.01e-7 Coronary artery disease; TGCT cis rs12711979 0.765 rs10208316 chr2:3827630 T/C cg17052675 chr2:3827356 NA -0.4 -7.89 -0.58 1.34e-12 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs5750830 0.649 rs4384886 chr22:39793766 C/T cg11247378 chr22:39784982 NA -0.75 -10.35 -0.68 1.8e-18 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.897 rs7432989 chr3:49105136 A/G cg07636037 chr3:49044803 WDR6 0.97 10.64 0.69 3.45e-19 Parkinson's disease; TGCT cis rs9512730 0.553 rs9507904 chr13:28049506 C/T cg04070771 chr13:27998621 GTF3A 0.52 4.57 0.38 1.18e-5 Schizophrenia; TGCT cis rs17376456 0.877 rs7736620 chr5:93305762 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.85 0.4 3.58e-6 Diabetic retinopathy; TGCT cis rs4506170 1.000 rs16902104 chr8:128340908 A/G cg07795030 chr8:128802207 NA 0.2 4.54 0.38 1.3e-5 Prostate cancer; TGCT cis rs6831352 0.819 rs1230155 chr4:99989259 C/T cg12011299 chr4:100065546 ADH4 0.38 5.07 0.41 1.43e-6 Alcohol dependence; TGCT cis rs9913156 0.793 rs11655166 chr17:4559302 T/A cg23387401 chr17:4582204 PELP1 -0.31 -4.62 -0.38 9.38e-6 Lymphocyte counts; TGCT cis rs2594989 0.831 rs7620624 chr3:11476270 C/G cg00170343 chr3:11313890 ATG7 0.74 5.52 0.44 1.9e-7 Circulating chemerin levels; TGCT cis rs586688 0.625 rs510576 chr1:201654962 G/T cg07139329 chr1:201708558 NAV1 -0.52 -5.32 -0.43 4.74e-7 Obesity-related traits; TGCT cis rs7599312 0.553 rs6710653 chr2:213404893 A/G cg20637307 chr2:213403960 ERBB4 0.91 11.8 0.73 5.21e-22 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs172166 0.652 rs476167 chr6:28065888 T/C cg10876282 chr6:28092338 ZSCAN16 0.51 4.79 0.39 4.75e-6 Cardiac Troponin-T levels; TGCT cis rs7226408 0.857 rs72890545 chr18:34603292 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs3733585 0.566 rs35955619 chr4:9918986 T/A cg00071950 chr4:10020882 SLC2A9 -0.47 -5.05 -0.41 1.53e-6 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs785422 0.867 rs785429 chr15:30188232 C/T cg10584986 chr15:29825929 FAM189A1 0.36 4.68 0.39 7.35e-6 Corneal structure; TGCT cis rs7617773 0.817 rs6787500 chr3:48299439 T/C cg11946769 chr3:48343235 NME6 0.74 7.03 0.53 1.21e-10 Coronary artery disease; TGCT cis rs7599312 0.534 rs7607363 chr2:213402705 A/G cg20637307 chr2:213403960 ERBB4 0.91 11.8 0.73 5.21e-22 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4888262 0.564 rs6564147 chr16:74622586 G/A cg01733217 chr16:74700730 RFWD3 0.74 7.42 0.55 1.6e-11 Testicular germ cell tumor; TGCT cis rs11785400 0.762 rs2280880 chr8:143721929 C/A cg24634471 chr8:143751801 JRK 0.53 5.07 0.41 1.42e-6 Schizophrenia; TGCT cis rs2816062 1.000 rs2816062 chr1:18903902 G/A cg18795169 chr1:18902165 NA -0.57 -12.35 -0.74 2.43e-23 Urate levels in lean individuals; TGCT cis rs3027009 0.881 rs3026955 chr1:159144034 C/A cg18972751 chr1:158261555 CD1C -0.46 -4.81 -0.4 4.27e-6 Lean body mass and age at menarche (combined); TGCT cis rs3008870 0.916 rs2025608 chr1:67422550 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.8 0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs35264875 1.000 rs72928636 chr11:68848386 C/T cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs6460942 0.915 rs7803051 chr7:12306904 A/T cg06484146 chr7:12443880 VWDE -0.45 -4.68 -0.39 7.41e-6 Coronary artery disease; TGCT cis rs6964587 0.839 rs9656002 chr7:91475007 A/G cg17063962 chr7:91808500 NA -0.87 -8.86 -0.62 6.91e-15 Breast cancer; TGCT cis rs7826238 0.524 rs2921055 chr8:8319342 C/A cg08975724 chr8:8085496 FLJ10661 0.6 5.45 0.44 2.59e-7 Systolic blood pressure; TGCT cis rs7618915 0.501 rs767418 chr3:52767427 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs1050631 1.000 rs1785919 chr18:33691964 G/A cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.98 0.41 2.07e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs6951245 1.000 rs78523927 chr7:1089458 T/C cg27454412 chr7:1067447 C7orf50 0.58 4.51 0.38 1.48e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611519 0.542 rs8139770 chr22:41416181 C/T cg13695892 chr22:41940480 POLR3H -0.54 -5.07 -0.41 1.42e-6 Neuroticism; TGCT cis rs9357506 1.000 rs6940858 chr6:46305042 A/G cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.37e-7 Body mass index; TGCT cis rs9952991 0.941 rs45450798 chr18:12792940 C/G cg24737193 chr18:12778029 NA -0.51 -5.35 -0.43 4.04e-7 Inflammatory skin disease; TGCT cis rs5769707 0.967 rs9616713 chr22:50049109 G/A cg20744362 chr22:50050164 C22orf34 0.29 4.76 0.39 5.41e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1048238 0.506 rs698890 chr1:16267371 C/G cg21385522 chr1:16154831 NA -0.61 -6.85 -0.52 3.07e-10 Systolic blood pressure; TGCT cis rs362272 0.545 rs2748447 chr4:3337831 G/A cg22655196 chr4:3374909 RGS12 0.22 4.52 0.38 1.43e-5 Serum sulfate level; TGCT cis rs727563 0.648 rs6002406 chr22:41965237 A/T cg06481639 chr22:41940642 POLR3H -0.72 -6.25 -0.49 6.08e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs57221529 0.766 rs4527146 chr5:555236 A/G cg09021430 chr5:549028 NA -0.41 -5.53 -0.44 1.81e-7 Lung disease severity in cystic fibrosis; TGCT cis rs7964899 0.611 rs4237951 chr12:14624574 A/C cg10925082 chr12:15114703 ARHGDIB -0.22 -4.51 -0.38 1.5e-5 Educational attainment (years of education); TGCT cis rs9303401 0.659 rs12602389 chr17:56779778 G/A cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs7223966 1.000 rs8077265 chr17:61732727 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 4.96 0.41 2.3e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs854765 0.583 rs11650890 chr17:17790882 C/T cg09796270 chr17:17721594 SREBF1 -0.27 -5.5 -0.44 2.04e-7 Total body bone mineral density; TGCT cis rs2458413 0.542 rs2458412 chr8:105363901 C/G cg04554929 chr8:105342491 NA 0.48 5.76 0.46 6.13e-8 Paget's disease; TGCT cis rs611744 0.967 rs627019 chr8:109222544 G/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7666738 0.830 rs17026973 chr4:98680041 T/A cg05340658 chr4:99064831 C4orf37 0.46 5.42 0.44 3.01e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs644799 1.000 rs546809 chr11:95579938 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.19 0.59 2.72e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3099143 1.000 rs4583202 chr15:77161676 G/A cg21673338 chr15:77095150 SCAPER 0.54 5.15 0.42 1.01e-6 Recalcitrant atopic dermatitis; TGCT trans rs901683 0.702 rs78757497 chr10:46161918 T/C cg03236627 chr11:44786104 TSPAN18 -0.58 -6.69 -0.51 6.68e-10 Red blood cell traits;Mean corpuscular volume; TGCT cis rs7769051 0.711 rs9493437 chr6:133088405 A/T cg22852734 chr6:133119734 C6orf192 1.18 6.54 0.51 1.46e-9 Type 2 diabetes nephropathy; TGCT cis rs6840360 0.615 rs72728179 chr4:152477877 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.703 rs10880264 chr12:42586535 A/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.56 5.18 0.42 8.7e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs35264875 0.851 rs72930611 chr11:68863659 G/T cg02660097 chr11:68866761 NA 0.32 4.61 0.38 9.94e-6 Blond vs. brown hair color; TGCT cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs17253792 0.822 rs77676035 chr14:56096229 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7772486 0.754 rs12199362 chr6:146118225 A/G cg23711669 chr6:146136114 FBXO30 0.93 10.49 0.69 8.22e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg04389838 chr3:44770851 ZNF501 -0.41 -5.7 -0.46 8.29e-8 Depressive symptoms; TGCT cis rs7208859 0.614 rs216412 chr17:28903394 A/G cg13385521 chr17:29058706 SUZ12P -0.71 -4.62 -0.38 9.65e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs909674 0.541 rs5757655 chr22:39797178 C/G cg11247378 chr22:39784982 NA 0.73 10.24 0.68 3.26e-18 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.16 0.42 9.48e-7 Menopause (age at onset); TGCT cis rs17376456 0.877 rs2085960 chr5:93399934 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs79149102 0.579 rs9673012 chr15:75293737 C/T cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT cis rs2797160 1.000 rs2747722 chr6:126009629 A/G cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs3806843 1.000 rs4451093 chr5:140158542 A/G cg19875535 chr5:140030758 IK -0.36 -6.19 -0.49 7.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs3741404 0.931 rs594942 chr11:64006292 T/C cg01727686 chr11:63997306 NUDT22;DNAJC4 -0.22 -4.6 -0.38 1.01e-5 Platelet count; TGCT cis rs7824557 0.628 rs11250129 chr8:11202154 G/A cg21775007 chr8:11205619 TDH 0.69 6.81 0.52 3.8e-10 Retinal vascular caliber; TGCT cis rs3008870 0.920 rs1925413 chr1:67417101 T/C cg03991309 chr1:68237761 GNG12 0.27 4.57 0.38 1.18e-5 Lymphocyte percentage of white cells; TGCT cis rs7582180 0.563 rs4851304 chr2:100963871 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs3087591 0.683 rs2525564 chr17:29652531 A/G cg24425628 chr17:29625626 OMG;NF1 0.39 5.74 0.46 6.74e-8 Hip circumference; TGCT cis rs910316 0.967 rs4903285 chr14:75609268 A/T cg11812906 chr14:75593930 NEK9 0.74 7.37 0.55 2.12e-11 Height; TGCT cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs763014 0.898 rs1981484 chr16:630710 A/G cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs7523273 0.565 rs2796234 chr1:207900695 T/A cg22525895 chr1:207977042 MIR29B2 -0.33 -5.31 -0.43 4.83e-7 Schizophrenia; TGCT cis rs6740322 0.748 rs13420649 chr2:43463637 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.08 -0.48 1.36e-8 Coronary artery disease; TGCT cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg05785598 chr3:49045655 WDR6 0.36 4.87 0.4 3.27e-6 Menarche (age at onset); TGCT cis rs1113500 0.575 rs1781067 chr1:108568011 C/T cg22161131 chr1:109420278 GPSM2 0.56 5.39 0.44 3.48e-7 Growth-regulated protein alpha levels; TGCT cis rs11809207 0.501 rs3762460 chr1:26495550 A/G cg24519413 chr1:26490540 NA 0.22 4.58 0.38 1.13e-5 Height; TGCT cis rs1129187 0.755 rs9471976 chr6:42920549 G/T cg17345569 chr6:42928274 GNMT -0.47 -4.8 -0.4 4.47e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9902453 0.967 rs8067576 chr17:28444254 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.56 0.51 1.32e-9 Coffee consumption (cups per day); TGCT cis rs6880778 0.505 rs7445978 chr5:40381056 A/T cg01087697 chr5:40835557 RPL37 0.55 5.1 0.42 1.22e-6 Inflammatory bowel disease; TGCT cis rs2594989 0.943 rs2454500 chr3:11500103 C/T cg00170343 chr3:11313890 ATG7 0.69 5.12 0.42 1.16e-6 Circulating chemerin levels; TGCT cis rs3096299 0.658 rs4785679 chr16:89566113 G/T cg02187348 chr16:89574699 SPG7 0.62 6.64 0.51 8.59e-10 Multiple myeloma (IgH translocation); TGCT cis rs3540 0.533 rs12916560 chr15:91056259 A/C cg22089800 chr15:90895588 ZNF774 -0.76 -7.96 -0.58 9.11e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs3008870 0.755 rs1024229 chr1:67512903 G/T cg02640540 chr1:67518911 SLC35D1 0.65 5.79 0.46 5.46e-8 Lymphocyte percentage of white cells; TGCT cis rs2742417 1.000 rs2742373 chr3:45784046 C/G cg04837898 chr3:45731254 SACM1L -0.53 -5.53 -0.45 1.78e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7909074 1.000 rs10751360 chr10:45396971 G/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.33 -0.43 4.38e-7 Mean corpuscular volume; TGCT cis rs4713118 0.629 rs203890 chr6:28022248 T/C cg12963246 chr6:28129442 ZNF389 0.45 4.55 0.38 1.27e-5 Parkinson's disease; TGCT cis rs3772130 0.962 rs13061326 chr3:121493125 T/C cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs9309473 0.519 rs2421586 chr2:73899719 C/T cg20560298 chr2:73613845 ALMS1 0.41 4.51 0.38 1.46e-5 Metabolite levels; TGCT cis rs9436747 0.641 rs1938486 chr1:66047125 T/C cg14976592 chr1:65886160 LEPROT;LEPR 0.56 5.03 0.41 1.69e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7267979 0.527 rs6076369 chr20:25576783 G/A cg03522245 chr20:25566470 NINL -0.44 -4.53 -0.38 1.35e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4372836 0.504 rs6730321 chr2:29004299 T/C cg09522027 chr2:28974177 PPP1CB -0.56 -5.75 -0.46 6.58e-8 Body mass index; TGCT cis rs6964587 0.839 rs10236107 chr7:91485461 G/A cg17063962 chr7:91808500 NA -0.85 -8.94 -0.63 4.52e-15 Breast cancer; TGCT cis rs868036 0.645 rs4776987 chr15:68123915 A/T cg05925327 chr15:68127851 NA 0.57 5.65 0.45 1.05e-7 Restless legs syndrome; TGCT cis rs6088580 0.624 rs6120645 chr20:33025171 C/T cg24642439 chr20:33292090 TP53INP2 0.49 4.5 0.37 1.55e-5 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.830 rs3846444 chr4:99032888 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs11785400 1.000 rs4297023 chr8:143733307 C/A cg24634471 chr8:143751801 JRK 0.56 6.12 0.48 1.13e-8 Schizophrenia; TGCT cis rs10782582 0.593 rs11163904 chr1:76121208 A/G cg22875332 chr1:76189707 ACADM 0.54 6.27 0.49 5.35e-9 Daytime sleep phenotypes; TGCT cis rs1534166 0.647 rs9876158 chr3:133508300 T/C cg08048268 chr3:133502702 NA 0.45 5.58 0.45 1.44e-7 Alcohol consumption (transferrin glycosylation); TGCT cis rs2760061 0.603 rs697761 chr1:228192397 G/A cg02753203 chr1:228287806 NA 0.38 7.5 0.56 1.04e-11 Diastolic blood pressure; TGCT cis rs11030122 0.673 rs10835474 chr11:4020819 G/T cg18678763 chr11:4115507 RRM1 -0.49 -6.04 -0.48 1.66e-8 Mean platelet volume;Platelet distribution width; TGCT trans rs208520 0.633 rs79679034 chr6:66701724 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.95 10.58 0.69 5e-19 Exhaled nitric oxide output; TGCT cis rs425277 0.539 rs3107142 chr1:2044542 T/C cg24578937 chr1:2090814 PRKCZ -0.24 -5.67 -0.45 9.32e-8 Height; TGCT cis rs57221529 0.766 rs12521051 chr5:560440 A/G cg09021430 chr5:549028 NA 0.41 5.69 0.46 8.58e-8 Lung disease severity in cystic fibrosis; TGCT cis rs7647973 1.000 rs6446275 chr3:49466871 A/G cg07636037 chr3:49044803 WDR6 -0.7 -5.73 -0.46 7.08e-8 Menarche (age at onset); TGCT trans rs4650994 0.544 rs4132058 chr1:178505557 A/C cg05059571 chr16:84539110 KIAA1609 -0.55 -11.43 -0.72 4.08e-21 HDL cholesterol levels;HDL cholesterol; TGCT cis rs873946 0.504 rs12775990 chr10:134575836 C/T cg18305652 chr10:134549665 INPP5A 0.33 5.55 0.45 1.65e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7917772 0.510 rs2001389 chr10:104375258 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2032447 0.831 rs9467664 chr6:26021813 A/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.98 10.7 0.69 2.55e-19 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.765 rs132915 chr22:41805782 T/C cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs731174 0.797 rs510208 chr1:38147166 A/G cg03714163 chr1:38157357 CDCA8;C1orf109 -0.43 -4.45 -0.37 1.89e-5 Prostate cancer (SNP x SNP interaction); TGCT cis rs7178572 0.568 rs3743479 chr15:77406396 A/G cg22256960 chr15:77711686 NA 0.85 8.61 0.61 2.75e-14 Type 2 diabetes; TGCT cis rs896854 0.548 rs574183 chr8:95973816 A/G cg09323728 chr8:95962352 TP53INP1 0.43 5.04 0.41 1.59e-6 Type 2 diabetes; TGCT cis rs7819412 0.669 rs28630509 chr8:10997039 A/G cg03192020 chr8:11204681 TDH -0.52 -4.5 -0.37 1.53e-5 Triglycerides; TGCT cis rs17443541 0.507 rs6755597 chr2:200451440 A/G cg00055341 chr2:200446845 NA -0.31 -4.45 -0.37 1.89e-5 Intelligence (multi-trait analysis); TGCT cis rs477895 0.568 rs34838337 chr11:63870892 T/C cg19465662 chr11:63993652 NUDT22;TRPT1 0.67 5.61 0.45 1.23e-7 Mean platelet volume; TGCT cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg07424592 chr7:64974309 NA 1.31 8.14 0.59 3.55e-13 Diabetic kidney disease; TGCT cis rs589448 0.902 rs315138 chr12:69764850 A/T cg20891283 chr12:69753455 YEATS4 0.9 10.36 0.68 1.69e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs992157 0.835 rs2271543 chr2:219142491 C/T cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs11577318 0.579 rs11548246 chr1:26697166 G/A cg14210634 chr1:25870291 LDLRAP1 0.53 4.61 0.38 9.8e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs1348850 0.874 rs6742951 chr2:178340766 G/C cg22681709 chr2:178499509 PDE11A -0.38 -4.54 -0.38 1.31e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs17253792 0.822 rs117050012 chr14:56038729 G/T cg01858014 chr14:56050164 KTN1 -0.36 -4.57 -0.38 1.15e-5 Putamen volume; TGCT cis rs12908161 1.000 rs11637142 chr15:85295927 A/G cg12863693 chr15:85201151 NMB 0.42 4.97 0.41 2.21e-6 Schizophrenia; TGCT cis rs35306767 0.714 rs11250228 chr10:1074887 A/G cg20503657 chr10:835505 NA 0.49 5.66 0.45 9.87e-8 Eosinophil percentage of granulocytes; TGCT cis rs9486715 1.000 rs9386670 chr6:97060688 C/A cg06623918 chr6:96969491 KIAA0776 -1.12 -13.69 -0.78 1.45e-26 Headache; TGCT cis rs2486288 0.656 rs11632419 chr15:45557456 C/A cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.34 -0.43 4.26e-7 Glomerular filtration rate; TGCT cis rs13082711 0.596 rs683503 chr3:27348094 C/T cg02860705 chr3:27208620 NA 0.34 5.36 0.43 3.99e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs6087771 0.650 rs6060395 chr20:30219823 G/C cg18721089 chr20:30220636 NA -0.43 -5.45 -0.44 2.6e-7 Subcortical brain region volumes;Putamen volume; TGCT cis rs2239547 0.522 rs2581815 chr3:52982159 C/G cg10802521 chr3:52805072 NEK4 -0.64 -6.17 -0.48 9.06e-9 Schizophrenia; TGCT trans rs7613875 0.600 rs1061474 chr3:50144951 T/C cg21659725 chr3:3221576 CRBN -0.65 -7.16 -0.54 6.39e-11 Body mass index; TGCT cis rs1799949 0.965 rs9897425 chr17:41430179 C/G cg23758822 chr17:41437982 NA 0.68 6.73 0.52 5.6e-10 Menopause (age at onset); TGCT cis rs4665809 1.000 rs12471809 chr2:26307140 A/G cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs2404602 0.647 rs11072618 chr15:77019342 A/G cg22467129 chr15:76604101 ETFA 0.47 4.7 0.39 6.84e-6 Blood metabolite levels; TGCT cis rs4237845 0.591 rs4760344 chr12:58320783 A/T cg02175503 chr12:58329896 NA 0.68 6.5 0.5 1.79e-9 Intelligence (multi-trait analysis); TGCT cis rs6933660 0.800 rs6930557 chr6:151755806 G/A cg14262678 chr6:151773367 RMND1;C6orf211 0.55 5.2 0.42 7.82e-7 Menarche (age at onset); TGCT cis rs514406 0.607 rs1930305 chr1:53195481 G/T cg16325326 chr1:53192061 ZYG11B -0.89 -13.12 -0.76 3.31e-25 Monocyte count; TGCT cis rs9653442 0.863 rs10865035 chr2:100835734 A/G cg07810366 chr2:100720526 AFF3 -0.45 -7.72 -0.57 3.4e-12 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs35934224 0.783 rs7286104 chr22:19861226 T/C cg11182965 chr22:19864308 TXNRD2 -0.38 -5.3 -0.43 5.04e-7 Glaucoma (primary open-angle); TGCT cis rs17539620 0.624 rs74551216 chr6:154840524 T/C cg20019720 chr6:154832845 CNKSR3 0.56 4.75 0.39 5.48e-6 Lipoprotein (a) levels; TGCT cis rs909674 0.818 rs5750830 chr22:39840828 C/A cg05872129 chr22:39784769 NA -0.99 -9.84 -0.66 3.06e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7017914 0.967 rs6991329 chr8:71593425 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs9902453 0.765 rs2628185 chr17:28070107 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.4 -0.6 8.88e-14 Coffee consumption (cups per day); TGCT cis rs1008375 0.900 rs1003413 chr4:17582442 C/T cg10189774 chr4:17578691 LAP3 -0.61 -5.17 -0.42 9.19e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs7618501 1.000 rs7374183 chr3:49785133 G/A cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT trans rs12655019 0.920 rs12654125 chr5:56215753 G/A cg25190722 chr1:3801660 DFFB 0.62 7.17 0.54 5.87e-11 Breast cancer (early onset); TGCT cis rs4523957 0.560 rs1994884 chr17:2084008 G/A cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7772486 0.754 rs702319 chr6:146006117 T/C cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs587847 0.597 rs17445101 chr15:37713464 G/A cg00216138 chr15:37171175 LOC145845 0.31 4.56 0.38 1.2e-5 Intraocular pressure; TGCT cis rs2124969 0.562 rs6750639 chr2:161066862 T/C cg03641300 chr2:160917029 PLA2R1 -0.19 -4.49 -0.37 1.62e-5 Waist circumference adjusted for body mass index; TGCT cis rs67311347 1.000 rs9822909 chr3:40457084 G/T cg13683864 chr3:40499215 RPL14 -1.16 -13.32 -0.77 1.14e-25 Renal cell carcinoma; TGCT cis rs1023500 0.573 rs2413666 chr22:42459622 C/T cg05082376 chr22:42548792 NA -0.23 -5.41 -0.44 3.14e-7 Schizophrenia; TGCT cis rs9660180 0.935 rs9786942 chr1:1759213 A/G cg03396347 chr1:1875803 NA -0.36 -6.48 -0.5 1.93e-9 Body mass index; TGCT cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg13695892 chr22:41940480 POLR3H 0.92 9.06 0.63 2.36e-15 Vitiligo; TGCT cis rs7819412 0.618 rs13276836 chr8:10981003 A/C cg21775007 chr8:11205619 TDH -0.53 -4.91 -0.4 2.79e-6 Triglycerides; TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg08859206 chr1:53392774 SCP2 0.42 6.43 0.5 2.54e-9 Monocyte count; TGCT cis rs9534288 0.797 rs7989351 chr13:46534080 C/A cg15192986 chr13:46630673 CPB2 -0.52 -7.28 -0.55 3.34e-11 Blood protein levels; TGCT cis rs79349575 0.783 rs62078372 chr17:47028989 T/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs1023500 0.505 rs134878 chr22:42663874 A/G cg15557168 chr22:42548783 NA -0.22 -5.17 -0.42 9.3e-7 Schizophrenia; TGCT cis rs8014252 0.711 rs58069917 chr14:71043557 C/T cg11204974 chr14:71022665 NA -0.54 -4.44 -0.37 2e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs6089584 0.816 rs4134440 chr20:60624296 A/G cg13665807 chr20:60559372 TAF4 -0.53 -5.41 -0.44 3.06e-7 Body mass index; TGCT cis rs1008375 0.900 rs4698622 chr4:17589557 C/T cg18681998 chr4:17616180 MED28 0.84 7.69 0.57 3.9e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6681544 0.544 rs6690951 chr1:82384961 G/A cg04226724 chr1:82268649 LPHN2 0.47 4.97 0.41 2.19e-6 Metabolite levels (X-11787); TGCT cis rs9902453 0.967 rs4994355 chr17:28386284 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs9527 0.637 rs12219247 chr10:104613361 A/G cg15744005 chr10:104629667 AS3MT -0.51 -6.51 -0.5 1.7e-9 Arsenic metabolism; TGCT cis rs7659604 0.540 rs11724322 chr4:122697850 A/T cg19748678 chr4:122722346 EXOSC9 -0.58 -5.85 -0.47 4.04e-8 Type 2 diabetes; TGCT cis rs4665809 0.590 rs13016300 chr2:26468365 G/C cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs4927850 0.918 rs4361313 chr3:195752260 A/G cg22891161 chr3:195456627 MUC20 -0.23 -5.38 -0.44 3.53e-7 Pancreatic cancer; TGCT cis rs4713118 0.568 rs9468213 chr6:27706180 G/A cg10876282 chr6:28092338 ZSCAN16 0.5 5.12 0.42 1.12e-6 Parkinson's disease; TGCT cis rs2862064 0.932 rs6870977 chr5:156446249 T/C cg12943317 chr5:156479607 HAVCR1 -0.45 -5.71 -0.46 7.96e-8 Platelet count; TGCT cis rs7267979 0.903 rs6132819 chr20:25218618 C/G cg16686733 chr20:25566563 NINL 0.59 6.06 0.48 1.53e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9914544 0.505 rs7503678 chr17:18776020 A/T cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.06e-6 Educational attainment (years of education); TGCT cis rs514406 0.800 rs7548519 chr1:53294473 A/G cg27535305 chr1:53392650 SCP2 -0.24 -4.49 -0.37 1.64e-5 Monocyte count; TGCT cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg23708337 chr7:1209742 NA 0.75 6.88 0.53 2.66e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7666738 0.578 rs1989109 chr4:98881246 T/A cg17366294 chr4:99064904 C4orf37 0.74 7.62 0.56 5.55e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs6964587 1.000 rs2285333 chr7:91667692 T/G cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs3213545 0.700 rs10849829 chr12:121470256 A/G cg15155738 chr12:121454335 C12orf43 -0.46 -4.54 -0.38 1.31e-5 Subjective well-being;Cardiovascular disease risk factors; TGCT cis rs9443189 0.526 rs6902898 chr6:76201856 G/A cg01950844 chr6:76311363 SENP6 0.92 5.57 0.45 1.48e-7 Prostate cancer; TGCT cis rs7703051 0.520 rs13354746 chr5:74619132 C/T cg19683494 chr5:74908142 NA 0.75 7.54 0.56 8.78e-12 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs7552404 0.731 rs11161845 chr1:76367559 T/C cg10523679 chr1:76189770 ACADM 0.85 7.54 0.56 8.71e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs561341 0.623 rs4795665 chr17:30233657 C/T cg13647721 chr17:30228624 UTP6 0.61 4.71 0.39 6.65e-6 Hip circumference adjusted for BMI; TGCT cis rs11792861 0.926 rs2271878 chr9:111868885 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.48 0.37 1.66e-5 Menarche (age at onset); TGCT cis rs611744 0.967 rs2597654 chr8:109221090 A/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg04944784 chr2:26401820 FAM59B -0.78 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT cis rs59107033 0.559 rs58531872 chr3:123105640 C/G cg04890266 chr3:123102914 ADCY5 -0.48 -7.84 -0.58 1.81e-12 Lymphocyte counts; TGCT trans rs877282 0.797 rs11253329 chr10:753200 A/T cg22713356 chr15:30763199 NA 1.07 8.27 0.6 1.75e-13 Uric acid levels; TGCT cis rs9368481 0.646 rs75843621 chr6:26967881 G/A cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.52 -5.85 -0.47 4.02e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs739496 0.615 rs4646778 chr12:112235783 C/A cg10833066 chr12:111807467 FAM109A 0.4 5.17 0.42 9.17e-7 Platelet count; TGCT cis rs2242116 1.000 rs2168443 chr3:46947087 A/T cg02527881 chr3:46936655 PTH1R 0.33 6.35 0.5 3.63e-9 Birth weight; TGCT cis rs7621025 0.630 rs1681818 chr3:136473673 A/G cg15507776 chr3:136538369 TMEM22 -0.5 -4.56 -0.38 1.22e-5 C-reactive protein levels or HDL-cholesterol levels (pleiotropy);Body mass index; TGCT cis rs2243480 1.000 rs4718270 chr7:65202407 A/G cg18252515 chr7:66147081 NA -1.17 -7.17 -0.54 5.94e-11 Diabetic kidney disease; TGCT cis rs4478858 0.735 rs6425736 chr1:31784376 T/A cg07478791 chr1:31886160 SERINC2 -0.52 -5.03 -0.41 1.67e-6 Alcohol dependence; TGCT cis rs4938534 0.716 rs7947717 chr11:111289738 T/C cg24049888 chr11:111250129 POU2AF1 -0.25 -4.44 -0.37 1.98e-5 Primary biliary cholangitis; TGCT cis rs7394190 0.748 rs2292307 chr10:75549916 C/A cg07699608 chr10:75541558 CHCHD1 0.79 5.45 0.44 2.63e-7 Incident atrial fibrillation; TGCT cis rs74233809 0.534 rs284844 chr10:104554529 A/G cg05855489 chr10:104503620 C10orf26 -0.76 -5.24 -0.43 6.78e-7 Birth weight; TGCT cis rs453301 0.624 rs6987558 chr8:8862521 C/G cg15556689 chr8:8085844 FLJ10661 0.73 6.43 0.5 2.47e-9 Joint mobility (Beighton score); TGCT cis rs17881320 0.510 rs6503699 chr17:40554261 C/G cg05878104 chr17:40932452 WNK4 0.9 5.93 0.47 2.76e-8 Atopic dermatitis; TGCT cis rs4631830 0.832 rs2843554 chr10:51523861 G/T cg10326726 chr10:51549505 MSMB -0.24 -4.9 -0.4 2.96e-6 Prostate-specific antigen levels; TGCT cis rs7666738 0.830 rs1115616 chr4:99006603 A/C cg05340658 chr4:99064831 C4orf37 0.49 5.51 0.44 1.97e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4727027 0.736 rs12704084 chr7:148915050 C/G cg23583168 chr7:148888333 NA -0.81 -10.36 -0.68 1.73e-18 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs10256972 0.869 rs4720158 chr7:1040325 A/G cg16145915 chr7:1198662 ZFAND2A -0.4 -4.76 -0.39 5.31e-6 Longevity;Endometriosis; TGCT cis rs7216064 1.000 rs6504549 chr17:65888784 A/G cg12091567 chr17:66097778 LOC651250 -0.84 -6.8 -0.52 4.01e-10 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs28595532 0.920 rs116428408 chr4:119758514 G/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs7575217 0.767 rs13386749 chr2:101746592 C/T cg12737833 chr2:101500543 NPAS2 0.28 4.58 0.38 1.09e-5 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; TGCT cis rs13394619 1.000 rs2358040 chr2:11731774 G/T cg07314298 chr2:11723111 GREB1 0.29 5.27 0.43 5.95e-7 Endometriosis; TGCT cis rs6815814 0.950 rs66979032 chr4:38814700 A/G cg02016764 chr4:38805732 TLR1 -0.34 -5.4 -0.44 3.26e-7 Breast cancer; TGCT cis rs4665809 1.000 rs4665821 chr2:26309949 A/C cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs6546537 1.000 rs4852868 chr2:69831636 C/T cg10773587 chr2:69614142 GFPT1 -0.64 -6.07 -0.48 1.41e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs6598955 0.724 rs869683 chr1:26570993 T/A cg04990556 chr1:26633338 UBXN11 -0.91 -11.99 -0.73 1.8e-22 Obesity-related traits; TGCT trans rs2108225 0.900 rs2395930 chr7:107451677 T/C cg14662119 chr1:153950267 JTB 0.66 6.67 0.51 7.48e-10 Ulcerative colitis; TGCT cis rs28785552 0.931 rs8112235 chr19:53239010 C/G cg22067481 chr19:53234126 ZNF611 -0.48 -6.78 -0.52 4.27e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs10751667 0.961 rs7395303 chr11:986221 T/A cg06064525 chr11:970664 AP2A2 -0.32 -6.43 -0.5 2.45e-9 Alzheimer's disease (late onset); TGCT cis rs7666738 0.830 rs11944855 chr4:99068258 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3733585 0.699 rs10001964 chr4:9959275 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.58 -0.51 1.2e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs13188771 0.690 rs350556 chr5:100860279 A/G cg10455971 chr5:101119566 NA -0.43 -4.53 -0.38 1.38e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs36051895 0.530 rs4142064 chr9:5221818 C/T cg02405213 chr9:5042618 JAK2 -0.63 -7.46 -0.56 1.29e-11 Pediatric autoimmune diseases; TGCT cis rs11671007 1 rs11671007 chr19:2893405 A/G cg08634464 chr19:2901147 ZNF57 -1.62 -6.91 -0.53 2.2e-10 Daytime sleep phenotypes; TGCT cis rs1372520 0.567 rs2619349 chr4:90746646 G/T cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs57994353 0.540 rs12379380 chr9:139279981 C/T cg13741927 chr9:139327495 INPP5E -0.21 -4.57 -0.38 1.15e-5 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs1552244 0.832 rs73024575 chr3:10198200 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 1.1 6.25 0.49 6.06e-9 Alzheimer's disease; TGCT cis rs77633900 0.614 rs2439991 chr15:76877227 A/G cg21673338 chr15:77095150 SCAPER -0.51 -4.7 -0.39 6.69e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs2153535 0.601 rs2327091 chr6:8540369 G/A cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs28595532 0.920 rs115006522 chr4:119732499 A/G cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs2742417 0.603 rs2742448 chr3:45764246 C/T cg04837898 chr3:45731254 SACM1L 0.64 6.79 0.52 4.13e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2239547 0.523 rs6803486 chr3:53098209 T/A cg11645453 chr3:52864694 ITIH4 0.3 4.83 0.4 3.88e-6 Schizophrenia; TGCT cis rs7582180 0.764 rs11683121 chr2:100920705 C/T cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.89e-7 Intelligence (multi-trait analysis); TGCT cis rs7674212 0.507 rs223471 chr4:103698786 G/C cg16532752 chr4:104119610 CENPE -0.6 -5.07 -0.41 1.42e-6 Type 2 diabetes; TGCT cis rs6976053 0.846 rs314375 chr7:100457344 G/A cg05669210 chr7:100450634 SLC12A9 0.51 4.45 0.37 1.87e-5 Plasminogen activator inhibitor type 1 levels (PAI-1); TGCT cis rs1348850 0.837 rs12619074 chr2:178472336 G/A cg22681709 chr2:178499509 PDE11A -0.48 -5.4 -0.44 3.2e-7 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT trans rs7726839 0.540 rs72705097 chr5:655067 G/A cg25482853 chr8:67687455 SGK3 1.2 10.13 0.67 6.02e-18 Obesity-related traits; TGCT trans rs561341 1.000 rs8064843 chr17:30245744 A/G cg20587970 chr11:113659929 NA -0.96 -12.13 -0.74 8.3300000000000006e-23 Hip circumference adjusted for BMI; TGCT cis rs10992471 0.603 rs1535755 chr9:95202031 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.67 -0.45 9.42e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1577917 1.000 rs12201735 chr6:86656939 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT trans rs7618501 0.602 rs6780731 chr3:50017478 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.88 9.71 0.66 6.38e-17 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.698 rs6429599 chr1:46827871 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs12286929 0.736 rs11215397 chr11:115044076 G/A cg04017736 chr11:115827165 NA -0.19 -4.47 -0.37 1.71e-5 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs500492 0.542 rs2573148 chr16:1073372 C/T cg01366354 chr16:1075121 NA 0.35 5.18 0.42 8.52e-7 Polycystic ovary syndrome; TGCT cis rs9914544 0.545 rs7212905 chr17:18774271 A/G cg26378065 chr17:18585709 ZNF286B 0.51 4.73 0.39 5.96e-6 Educational attainment (years of education); TGCT cis rs7829975 0.774 rs35431455 chr8:8673736 T/C cg06636001 chr8:8085503 FLJ10661 0.65 5.73 0.46 7.34e-8 Mood instability; TGCT cis rs6746896 0.959 rs56351161 chr2:97373817 G/A cg26085987 chr2:97230376 NA 0.19 4.71 0.39 6.5e-6 Bipolar disorder; TGCT cis rs35883536 0.565 rs2809813 chr1:101032003 A/C cg10298815 chr1:101004474 GPR88 0.25 4.69 0.39 7.06e-6 Monocyte count; TGCT cis rs860295 0.557 rs915181 chr1:155914772 C/T cg05700447 chr1:155978627 NA 0.21 4.44 0.37 1.97e-5 Body mass index; TGCT cis rs922182 0.617 rs28621460 chr15:64240232 C/T cg02919090 chr15:64263738 DAPK2 0.37 7.01 0.53 1.35e-10 Blood protein levels; TGCT cis rs9381040 0.610 rs2268195 chr6:41024340 G/A cg03526776 chr6:41159608 TREML2 0.27 5.29 0.43 5.37e-7 Alzheimer's disease (late onset); TGCT cis rs7940866 0.903 rs10791109 chr11:130850377 A/C cg12179176 chr11:130786555 SNX19 0.52 5.06 0.41 1.46e-6 Schizophrenia; TGCT cis rs2369473 1 rs2369473 chr1:160210727 C/A cg07195126 chr1:160370843 VANGL2 0.58 5.11 0.42 1.17e-6 Squamous cell lung carcinoma; TGCT cis rs9952991 0.566 rs487273 chr18:12853458 T/G cg23544223 chr18:12777786 NA 0.55 4.88 0.4 3.22e-6 Inflammatory skin disease; TGCT cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs60871478 0.730 rs62432226 chr7:792973 T/C cg05729249 chr7:766119 PRKAR1B;HEATR2 0.46 4.47 0.37 1.75e-5 Cerebrospinal P-tau181p levels; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg09033563 chr22:24373618 LOC391322 0.49 4.79 0.4 4.64e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467773 1.000 rs9467782 chr6:26542773 G/A cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs7940866 0.874 rs1433979 chr11:130871617 G/A cg05962950 chr11:130786565 SNX19 0.6 6.06 0.48 1.52e-8 Schizophrenia; TGCT cis rs10504229 0.679 rs16921676 chr8:58052386 G/T cg20607798 chr8:58055168 NA 0.44 4.6 0.38 1.04e-5 Developmental language disorder (linguistic errors); TGCT cis rs8014204 0.541 rs35591392 chr14:75157713 G/T cg06637938 chr14:75390232 RPS6KL1 0.64 5.87 0.47 3.74e-8 Caffeine consumption; TGCT cis rs7937682 0.632 rs1045282 chr11:111754574 A/C cg09085632 chr11:111637200 PPP2R1B 0.84 7.27 0.55 3.45e-11 Primary sclerosing cholangitis; TGCT cis rs10504229 0.906 rs67389108 chr8:58193718 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs9296092 0.521 rs56332659 chr6:33537887 T/C cg13560919 chr6:33536144 NA -0.21 -4.71 -0.39 6.66e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs523522 0.962 rs2393590 chr12:120913900 G/A cg27279351 chr12:120934652 DYNLL1 0.76 6.58 0.51 1.19e-9 High light scatter reticulocyte count; TGCT trans rs8073060 0.660 rs58266733 chr17:34003812 A/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT trans rs1387416 1.000 rs9352077 chr6:74890635 C/T cg19320816 chr6:26087776 HFE -0.54 -6.66 -0.51 8.1e-10 Acute graft versus host disease in bone marrow transplantation (donor effect); TGCT cis rs11252926 0.502 rs7072510 chr10:455596 C/T cg13477178 chr10:375248 DIP2C -0.24 -4.57 -0.38 1.14e-5 Psychosis in Alzheimer's disease; TGCT trans rs57221529 0.709 rs111352378 chr5:577079 G/A cg11887960 chr12:57824829 NA 1.1 9.44 0.65 2.89e-16 Lung disease severity in cystic fibrosis; TGCT cis rs4372836 0.964 rs2045884 chr2:28964355 C/T cg09522027 chr2:28974177 PPP1CB -0.54 -4.6 -0.38 1.04e-5 Body mass index; TGCT cis rs6545883 0.868 rs6748003 chr2:61806700 T/G cg15711740 chr2:61764176 XPO1 -0.59 -5.7 -0.46 8.42e-8 Tuberculosis; TGCT cis rs6598955 0.671 rs10902732 chr1:26606174 A/C cg04990556 chr1:26633338 UBXN11 0.66 5.0 0.41 1.88e-6 Obesity-related traits; TGCT cis rs344364 0.511 rs337284 chr16:1954799 A/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.47 -5.43 -0.44 2.8e-7 Glomerular filtration rate in chronic kidney disease; TGCT cis rs10504229 0.683 rs34804288 chr8:58117570 C/A cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs6882076 0.961 rs4704827 chr5:156392089 T/C cg12943317 chr5:156479607 HAVCR1 -0.31 -6.09 -0.48 1.31e-8 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs11785400 1.000 rs4736365 chr8:143742197 A/G cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg05665937 chr4:1216051 CTBP1 0.24 4.61 0.38 1e-5 Obesity-related traits; TGCT cis rs62064224 0.902 rs17732573 chr17:30627664 C/T cg18200150 chr17:30822561 MYO1D -0.45 -5.94 -0.47 2.7e-8 Schizophrenia; TGCT cis rs11190604 0.767 rs7392696 chr10:102182141 G/A cg16342193 chr10:102329863 NA -0.4 -5.02 -0.41 1.74e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9325144 0.647 rs35254764 chr12:39102928 T/C cg26384229 chr12:38710491 ALG10B -0.57 -5.29 -0.43 5.23e-7 Morning vs. evening chronotype; TGCT cis rs593982 0.920 rs488170 chr11:65481544 T/C cg08755490 chr11:65554678 OVOL1 1.34 8.14 0.59 3.53e-13 Atopic dermatitis; TGCT cis rs7937612 1.000 rs9633950 chr11:120248249 T/G cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.58 -0.38 1.1e-5 Intraocular pressure; TGCT cis rs7772486 0.743 rs62433835 chr6:146032688 C/G cg05347473 chr6:146136440 FBXO30 -0.5 -4.75 -0.39 5.58e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs11122272 0.706 rs2749710 chr1:231535112 A/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.69 6.9 0.53 2.38e-10 Hemoglobin concentration; TGCT cis rs9906944 0.545 rs1994969 chr17:47080431 G/T cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg13395646 chr4:1353034 KIAA1530 -0.36 -4.61 -0.38 9.75e-6 Obesity-related traits; TGCT cis rs2832191 0.692 rs2776240 chr21:30310639 C/T cg24692254 chr21:30365293 RNF160 0.92 10.49 0.69 8.31e-19 Dental caries; TGCT cis rs28493229 0.708 rs78084428 chr19:41160097 G/A cg11601297 chr19:41224147 ITPKC;ADCK4 0.57 5.15 0.42 9.78e-7 Kawasaki disease; TGCT cis rs7014346 0.767 rs11784983 chr8:128421348 A/G cg04263511 chr8:128962092 PVT1 -0.31 -4.55 -0.38 1.25e-5 Colorectal cancer; TGCT cis rs1005277 0.579 rs2474595 chr10:38426782 C/G cg13531842 chr10:38383804 ZNF37A 0.39 4.58 0.38 1.13e-5 Extrinsic epigenetic age acceleration; TGCT cis rs8177253 0.665 rs6774822 chr3:133442012 G/T cg01448562 chr3:133502909 NA -0.28 -5.27 -0.43 5.8e-7 Iron status biomarkers; TGCT cis rs951366 0.903 rs823114 chr1:205719532 G/A cg07167872 chr1:205819463 PM20D1 0.41 4.77 0.39 4.98e-6 Menarche (age at onset); TGCT cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.89 9.91 0.66 2.06e-17 Platelet count; TGCT cis rs13118159 0.527 rs6599309 chr4:1388115 C/G cg16405210 chr4:1374714 KIAA1530 -0.25 -4.5 -0.37 1.54e-5 Longevity; TGCT cis rs593982 0.920 rs76925283 chr11:65548108 C/T cg08755490 chr11:65554678 OVOL1 -1.49 -10.9 -0.7 8.17e-20 Atopic dermatitis; TGCT cis rs7605378 1.000 rs7577763 chr2:200681753 C/T cg17644776 chr2:200775616 C2orf69 0.29 5.51 0.44 1.94e-7 Osteoporosis; TGCT cis rs931608 0.640 rs4932758 chr19:22540094 G/A cg23859931 chr19:22123797 NA -0.64 -4.8 -0.4 4.43e-6 Dental caries;Response to statins (LDL cholesterol change); TGCT cis rs10088262 0.527 rs3911939 chr8:124793744 T/G cg20713898 chr8:124780851 FAM91A1 -0.75 -5.46 -0.44 2.45e-7 Pancreatic cancer; TGCT cis rs1215050 0.740 rs804051 chr4:98935935 A/T cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.12e-8 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs2727020 0.619 rs1164665 chr11:49295630 T/C cg11707556 chr5:10655725 ANKRD33B 0.38 6.8 0.52 3.89e-10 Coronary artery disease; TGCT cis rs10992471 0.605 rs7872375 chr9:95064843 C/G cg14631576 chr9:95140430 CENPP -0.28 -4.65 -0.39 8.23e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1008375 0.932 rs13127157 chr4:17618049 A/G cg10189774 chr4:17578691 LAP3 -0.62 -5.21 -0.42 7.77e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs950776 0.593 rs481134 chr15:78877563 C/T cg06917634 chr15:78832804 PSMA4 0.66 5.35 0.43 4.17e-7 Sudden cardiac arrest; TGCT cis rs875971 0.862 rs4149461 chr7:65744732 T/C cg11764359 chr7:65958608 NA -0.57 -5.12 -0.42 1.12e-6 Aortic root size; TGCT cis rs514406 0.505 rs835609 chr1:53170494 T/C cg08859206 chr1:53392774 SCP2 -0.35 -4.89 -0.4 3.1e-6 Monocyte count; TGCT cis rs57994353 0.759 rs35873563 chr9:139324029 C/T cg13741927 chr9:139327495 INPP5E -0.27 -6.02 -0.48 1.83e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs17253792 0.822 rs76055105 chr14:56069127 A/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs595982 0.517 rs4801779 chr19:49406651 T/G cg15549821 chr19:49342101 PLEKHA4 -0.4 -5.48 -0.44 2.32e-7 Red cell distribution width; TGCT cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg06481639 chr22:41940642 POLR3H -0.75 -6.47 -0.5 2.1e-9 Vitiligo; TGCT cis rs514406 0.861 rs35581164 chr1:53271373 C/G cg08736216 chr1:53307985 ZYG11A -0.25 -4.86 -0.4 3.42e-6 Monocyte count; TGCT cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs4824093 0.610 rs7410534 chr22:50289925 C/T cg20569369 chr22:51173646 NA 0.29 4.76 0.39 5.26e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs7552404 0.690 rs7549863 chr1:76327923 T/C cg10523679 chr1:76189770 ACADM -0.67 -6.27 -0.49 5.47e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6831352 0.801 rs2602897 chr4:100046293 A/T cg12011299 chr4:100065546 ADH4 0.41 4.92 0.4 2.72e-6 Alcohol dependence; TGCT cis rs9790314 0.846 rs4856714 chr3:160961824 T/C cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs12477438 0.715 rs7586608 chr2:99558017 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.75 -7.31 -0.55 2.9100000000000002e-11 Chronic sinus infection; TGCT cis rs11585357 0.895 rs72633803 chr1:17616758 G/A cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs10193935 0.901 rs2286702 chr2:42555473 C/T cg27598129 chr2:42591480 NA -0.41 -5.68 -0.45 9.25e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.775 rs11182513 chr12:38560252 G/C cg26384229 chr12:38710491 ALG10B 0.89 8.1 0.59 4.28e-13 Bladder cancer; TGCT cis rs7659604 0.540 rs10004284 chr4:122699222 A/T cg06713675 chr4:122721982 EXOSC9 0.36 4.52 0.38 1.42e-5 Type 2 diabetes; TGCT cis rs10779751 0.770 rs11121695 chr1:11229515 G/A cg08854313 chr1:11322531 MTOR -0.84 -6.81 -0.52 3.82e-10 Body mass index; TGCT cis rs6565180 1.000 rs11863150 chr16:30385503 C/T cg17640201 chr16:30407289 ZNF48 0.93 9.48 0.65 2.33e-16 Tonsillectomy; TGCT cis rs1056107 0.931 rs7864927 chr9:115003993 C/T cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs13108904 0.901 rs1316393 chr4:1315619 A/G cg13395646 chr4:1353034 KIAA1530 0.47 6.15 0.48 9.8e-9 Obesity-related traits; TGCT cis rs523522 0.962 rs9788155 chr12:120938408 G/A cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs1723838 0.510 rs17132534 chr11:73691774 A/G cg26954736 chr11:73693896 UCP2 -1.37 -6.3 -0.49 4.64e-9 Obesity-related traits; TGCT cis rs12541335 0.639 rs68063696 chr8:22153236 A/G cg02788857 chr8:22132959 PIWIL2 0.26 4.57 0.38 1.16e-5 Hypertriglyceridemia; TGCT cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg21724239 chr8:58056113 NA 0.5 5.43 0.44 2.83e-7 Developmental language disorder (linguistic errors); TGCT cis rs7772486 0.641 rs9390370 chr6:146357569 C/T cg23711669 chr6:146136114 FBXO30 0.68 6.55 0.51 1.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs13082711 0.640 rs35903173 chr3:27287751 T/C cg02860705 chr3:27208620 NA 0.55 8.42 0.6 7.68e-14 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs797680 0.786 rs6694508 chr1:93842023 A/C cg17826107 chr1:92977322 EVI5 -0.24 -5.63 -0.45 1.13e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10504229 0.593 rs10504216 chr8:57981470 G/A cg20607798 chr8:58055168 NA 0.58 4.67 0.39 7.56e-6 Developmental language disorder (linguistic errors); TGCT cis rs6921919 0.583 rs4642462 chr6:28389251 G/C cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.24 -0.43 6.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6912958 0.754 rs7762864 chr6:88236213 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs6840360 0.593 rs1429558 chr4:152685406 A/T cg17479576 chr4:152424074 FAM160A1 -0.52 -5.16 -0.42 9.49e-7 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs4687638 chr3:52651966 A/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.07 0.48 1.47e-8 Bipolar disorder; TGCT cis rs2549003 1.000 rs9282762 chr5:131822055 T/C cg02551604 chr5:131831745 NA -0.9 -12.1 -0.74 9.75e-23 Asthma (sex interaction); TGCT cis rs3096299 0.719 rs2965818 chr16:89510494 A/G cg08392591 chr16:89556376 ANKRD11 0.63 6.08 0.48 1.38e-8 Multiple myeloma (IgH translocation); TGCT cis rs3096299 0.566 rs4129126 chr16:89561475 A/C cg02244288 chr16:89573955 SPG7 -0.32 -4.56 -0.38 1.22e-5 Multiple myeloma (IgH translocation); TGCT cis rs4699052 0.590 rs4698892 chr4:104261271 C/G cg16532752 chr4:104119610 CENPE -0.51 -5.01 -0.41 1.8e-6 Testicular germ cell tumor; TGCT cis rs8017423 0.565 rs4904681 chr14:90835566 A/T cg04374321 chr14:90722782 PSMC1 -0.55 -5.26 -0.43 6.23e-7 Mortality in heart failure; TGCT cis rs12134133 1.000 rs11580387 chr1:207418408 A/G cg02152968 chr1:207494213 CD55 0.61 4.83 0.4 3.92e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs9527 0.544 rs11191549 chr10:104846797 C/T cg15744005 chr10:104629667 AS3MT -0.42 -4.84 -0.4 3.82e-6 Arsenic metabolism; TGCT trans rs1005277 0.522 rs1208684 chr10:38093936 G/A cg17830980 chr10:43048298 ZNF37B -0.65 -7.49 -0.56 1.11e-11 Extrinsic epigenetic age acceleration; TGCT cis rs12681287 0.640 rs13253296 chr8:87448245 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT trans rs8073060 0.586 rs7212488 chr17:33993476 A/T cg19694781 chr19:47549865 TMEM160 -0.62 -14.07 -0.78 1.86e-27 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT trans rs6089829 0.962 rs6122352 chr20:61668284 T/C cg23505145 chr19:12996616 KLF1 0.78 8.06 0.59 5.54e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs17826219 0.714 rs11650821 chr17:28968150 T/C cg13385521 chr17:29058706 SUZ12P 0.81 4.87 0.4 3.39e-6 Body mass index; TGCT cis rs3741404 0.665 rs594461 chr11:63872543 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.74 7.52 0.56 9.8e-12 Platelet count; TGCT cis rs9527 0.545 rs10218853 chr10:104796787 A/C cg04362960 chr10:104952993 NT5C2 0.68 5.73 0.46 7.14e-8 Arsenic metabolism; TGCT cis rs10504229 1.000 rs76270388 chr8:58195605 T/A cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs2439831 0.681 rs484846 chr15:43600803 T/C cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.69 0.62 1.84e-14 Lung cancer in ever smokers; TGCT cis rs11676348 0.755 rs1008562 chr2:219026972 G/C cg00012203 chr2:219082015 ARPC2 0.53 4.89 0.4 3.01e-6 Ulcerative colitis; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg04234412 chr22:24373322 LOC391322 -0.94 -11.56 -0.72 2.03e-21 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9399137 0.507 rs11753673 chr6:135316476 T/C cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs4975616 0.836 rs421629 chr5:1320136 G/A cg07493874 chr5:1342172 CLPTM1L -0.28 -6.59 -0.51 1.15e-9 Lung cancer; TGCT cis rs2688608 1.000 rs2675680 chr10:75658864 T/C cg19442545 chr10:75533431 FUT11 -0.3 -4.8 -0.4 4.49e-6 Inflammatory bowel disease; TGCT cis rs7568458 0.684 rs7608074 chr2:85809703 T/G cg02493740 chr2:85810744 VAMP5 -0.31 -5.74 -0.46 6.97e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6490294 0.904 rs12306814 chr12:112403813 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Mean platelet volume; TGCT cis rs9969804 0.782 rs912262 chr9:95525557 C/T cg13940029 chr9:95239186 CENPP;ASPN 0.17 4.58 0.38 1.11e-5 Height; TGCT cis rs2071303 0.836 rs198835 chr6:26113994 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.72 -6.87 -0.53 2.76e-10 Intelligence (multi-trait analysis); TGCT cis rs6547741 1.000 rs1528402 chr2:27857517 G/A cg27432699 chr2:27873401 GPN1 0.18 4.63 0.38 9.05e-6 Oral cavity cancer; TGCT cis rs6554196 0.686 rs723585 chr4:55503194 A/G cg02821500 chr4:54931072 CHIC2 0.46 4.44 0.37 1.95e-5 Monocyte count; TGCT cis rs2762353 0.808 rs1183201 chr6:25823444 A/T cg12310025 chr6:25882481 NA -0.59 -6.04 -0.48 1.65e-8 Blood metabolite levels; TGCT cis rs9325144 0.532 rs12812406 chr12:38719802 G/A cg26384229 chr12:38710491 ALG10B -0.63 -5.91 -0.47 3.03e-8 Morning vs. evening chronotype; TGCT cis rs2762353 0.935 rs1177442 chr6:25809069 A/G cg03264133 chr6:25882463 NA -0.51 -5.36 -0.43 3.84e-7 Blood metabolite levels; TGCT cis rs7216064 1.000 rs12600941 chr17:65918807 A/G cg12091567 chr17:66097778 LOC651250 -0.78 -5.57 -0.45 1.51e-7 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs7666738 0.830 rs13118945 chr4:98968586 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 0.698 rs67276232 chr1:46825484 T/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs4494114 1.000 rs12037982 chr1:39358600 G/A cg25970120 chr1:39325951 RRAGC -0.6 -6.17 -0.48 8.89e-9 Blood protein levels; TGCT cis rs1153858 0.943 rs12439575 chr15:45684816 T/G cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs6450176 1.000 rs6450176 chr5:53298025 G/A ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.11 -0.42 1.17e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs10256972 0.684 rs4724039 chr7:1111633 A/G cg09177884 chr7:1199841 ZFAND2A -0.55 -5.37 -0.43 3.68e-7 Longevity;Endometriosis; TGCT cis rs4149178 0.656 rs3734683 chr6:43316023 A/G cg07522644 chr6:43142093 SRF 0.7 4.99 0.41 1.96e-6 Urate levels; TGCT cis rs231513 0.911 rs231527 chr17:41951228 T/C cg26893861 chr17:41843967 DUSP3 -0.87 -6.27 -0.49 5.58e-9 Cognitive function; TGCT cis rs13217239 0.646 rs10946888 chr6:26951678 A/G cg05738196 chr6:26577821 NA 0.49 4.67 0.39 7.73e-6 Schizophrenia; TGCT cis rs10992471 0.603 rs10114912 chr9:95307863 C/A cg13798575 chr9:95087839 CENPP;NOL8 -0.6 -5.68 -0.45 9.01e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6089829 0.851 rs6122346 chr20:61661822 C/G cg08564027 chr20:61660810 NA 0.38 7.08 0.54 9.36e-11 Prostate cancer (SNP x SNP interaction); TGCT cis rs13191362 1.000 rs13209728 chr6:162997533 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs492146 0.765 rs316133 chr6:52847551 C/G cg06706454 chr6:52930286 FBXO9 -0.5 -4.7 -0.39 6.83e-6 Epilepsy (remission after treatment); TGCT cis rs1153858 1.000 rs7167900 chr15:45639471 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs10504229 0.953 rs75253516 chr8:58171547 C/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2657888 0.965 rs2657905 chr12:56935402 T/A cg23002907 chr12:56915593 RBMS2 0.44 6.15 0.48 9.65e-9 Adiponectin levels; TGCT cis rs7809950 1.000 rs2894475 chr7:107262558 A/T cg23024343 chr7:107201750 COG5 -0.32 -5.0 -0.41 1.93e-6 Coronary artery disease; TGCT cis rs62244186 0.659 rs56231820 chr3:44530329 C/T cg21672276 chr3:44754072 ZNF502 -0.41 -4.63 -0.38 9.03e-6 Depressive symptoms; TGCT cis rs6977940 0.512 rs6461600 chr7:2816537 C/T cg19731401 chr7:2775893 GNA12 0.32 4.57 0.38 1.15e-5 White matter integrity; TGCT cis rs3008870 0.755 rs2815362 chr1:67496803 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.82 8.67 0.61 1.95e-14 Lymphocyte percentage of white cells; TGCT cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9913156 0.748 rs72835619 chr17:4557285 G/A cg19197139 chr17:4613644 ARRB2 0.86 7.9 0.58 1.32e-12 Lymphocyte counts; TGCT cis rs7226408 0.802 rs72885272 chr18:34437656 A/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs12902680 0.739 rs1607719 chr15:46419008 G/A cg13605988 chr15:45421612 DUOX1;DUOXA1 0.33 4.62 0.38 9.28e-6 Neuroticism; TGCT cis rs7412746 0.611 rs10888394 chr1:150749913 C/T cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs739401 0.572 rs404629 chr11:3077025 A/G cg05729581 chr11:3078854 CARS -0.58 -5.31 -0.43 4.93e-7 Longevity; TGCT cis rs10875595 0.836 rs1363450 chr5:140658363 A/T cg20560182 chr5:140700478 TAF7 0.64 4.92 0.4 2.64e-6 Pulmonary function decline; TGCT cis rs1552244 0.572 rs3894321 chr3:10168892 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -5.79 -0.46 5.39e-8 Alzheimer's disease; TGCT cis rs1580019 0.587 rs7806113 chr7:32553084 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.98 0.41 2.05e-6 Cognitive ability; TGCT cis rs3820928 1.000 rs2163041 chr2:227772480 T/C cg11843606 chr2:227700838 RHBDD1 -0.54 -4.82 -0.4 4.12e-6 Pulmonary function; TGCT cis rs262150 0.625 rs55974535 chr7:158769145 C/G cg01219135 chr7:158766336 NA -0.51 -5.34 -0.43 4.25e-7 Facial morphology (factor 20); TGCT cis rs12210905 0.610 rs72845033 chr6:27546262 C/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7772486 0.875 rs9403768 chr6:146406458 A/C cg13319975 chr6:146136371 FBXO30 -0.52 -4.6 -0.38 1.04e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7617773 0.539 rs2017859 chr3:48382261 G/A cg11946769 chr3:48343235 NME6 0.55 4.6 0.38 1.02e-5 Coronary artery disease; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg11905131 chr22:24372483 LOC391322 0.87 10.19 0.68 4.43e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467773 0.933 rs2024970 chr6:26497520 T/A cg05738196 chr6:26577821 NA 0.72 7.91 0.58 1.25e-12 Intelligence (multi-trait analysis); TGCT cis rs4654899 0.931 rs935917 chr1:21167102 A/T cg01072550 chr1:21505969 NA -0.5 -7.75 -0.57 2.84e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7091068 0.659 rs10732241 chr10:95468573 T/C cg20715218 chr10:95462985 C10orf4 0.55 5.18 0.42 8.59e-7 Urinary tract infection frequency; TGCT cis rs67478160 0.643 rs8003653 chr14:104298836 A/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs9303401 0.614 rs12950028 chr17:56510140 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.58 6.1 0.48 1.23e-8 Cognitive test performance; TGCT cis rs1372520 0.684 rs2583978 chr4:90750326 A/C cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT cis rs10465746 0.780 rs11163866 chr1:84367123 A/G cg10977910 chr1:84465055 TTLL7 0.66 6.56 0.51 1.31e-9 Obesity-related traits; TGCT cis rs9303401 0.614 rs34843288 chr17:57103140 T/C cg25039879 chr17:56429692 SUPT4H1 0.55 4.93 0.4 2.63e-6 Cognitive test performance; TGCT cis rs17345786 1.000 rs7641261 chr3:101279006 C/T cg12386194 chr3:101231763 SENP7 0.59 5.45 0.44 2.64e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9921338 0.924 rs72773831 chr16:11412927 G/A cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4851266 0.966 rs11689199 chr2:100820421 A/G cg07810366 chr2:100720526 AFF3 -0.4 -5.74 -0.46 6.97e-8 Educational attainment; TGCT cis rs9611565 0.921 rs5751080 chr22:41736267 A/G cg17554472 chr22:41940697 POLR3H -0.4 -4.58 -0.38 1.11e-5 Vitiligo; TGCT cis rs6500602 0.929 rs6500603 chr16:4497537 G/C cg14951292 chr16:4525986 HMOX2;NMRAL1 0.29 4.81 0.4 4.37e-6 Schizophrenia; TGCT cis rs9291683 0.575 rs3756223 chr4:10105797 C/T cg00071950 chr4:10020882 SLC2A9 0.45 4.52 0.38 1.44e-5 Bone mineral density; TGCT cis rs10114408 0.959 rs7874271 chr9:96638818 C/A cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1538970 0.816 rs61788356 chr1:46006675 C/T cg05343316 chr1:45956843 TESK2 0.7 5.48 0.44 2.29e-7 Platelet count; TGCT cis rs67311347 1.000 rs66841330 chr3:40531123 G/A cg13683864 chr3:40499215 RPL14 -1.19 -12.73 -0.75 2.99e-24 Renal cell carcinoma; TGCT cis rs751728 1.000 rs4713684 chr6:33766488 T/C cg13859433 chr6:33739653 LEMD2 -0.39 -6.99 -0.53 1.51e-10 Crohn's disease; TGCT cis rs10489202 0.608 rs6657019 chr1:168079669 T/C cg24449463 chr1:168025552 DCAF6 -0.49 -5.06 -0.41 1.45e-6 Schizophrenia; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg15242686 chr22:24348715 GSTTP1 0.43 5.85 0.47 4.12e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11920354 0.513 rs62248910 chr3:47302036 G/A cg27129171 chr3:47204927 SETD2 -0.67 -5.08 -0.41 1.38e-6 Granulocyte count;Sum neutrophil eosinophil counts; TGCT cis rs6693567 0.545 rs7553647 chr1:150472666 C/T cg09579323 chr1:150459698 TARS2 0.53 4.63 0.38 9.01e-6 Migraine; TGCT cis rs116095464 0.764 rs10069197 chr5:230822 G/C cg22857025 chr5:266934 NA -0.32 -6.58 -0.51 1.18e-9 Breast cancer; TGCT cis rs10504229 1.000 rs57941207 chr8:58169821 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs4642101 0.824 rs9825233 chr3:12843368 A/G cg05775895 chr3:12838266 CAND2 -0.72 -7.15 -0.54 6.58e-11 QRS complex (12-leadsum); TGCT cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs3087591 0.708 rs10438801 chr17:29693785 G/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.66 0.45 1.01e-7 Hip circumference; TGCT cis rs9677476 0.516 rs6749 chr2:232035429 G/A cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 15.94 0.82 8.5e-32 Prudent dietary pattern; TGCT cis rs734999 0.505 rs10797439 chr1:2540364 G/A cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs4975709 0.589 rs1466606 chr5:1865055 C/T cg04156016 chr5:1868137 NA 0.35 5.08 0.42 1.33e-6 Cardiovascular disease risk factors; TGCT cis rs17030434 0.906 rs4145339 chr4:154710481 C/T cg14289246 chr4:154710475 SFRP2 -0.99 -7.77 -0.57 2.51e-12 Electrocardiographic conduction measures; TGCT trans rs11671005 0.504 rs2305119 chr19:59067623 C/T cg22037779 chr5:139682734 PFDN1 -0.86 -6.8 -0.52 4.03e-10 Mean platelet volume; TGCT cis rs7666738 0.546 rs10018080 chr4:98758436 C/A cg17366294 chr4:99064904 C4orf37 0.62 5.77 0.46 6.03e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7659604 1.000 rs7689714 chr4:122665943 T/A cg19748678 chr4:122722346 EXOSC9 0.55 5.31 0.43 4.92e-7 Type 2 diabetes; TGCT cis rs727563 0.608 rs2076200 chr22:41985956 G/T cg03806693 chr22:41940476 POLR3H -1.11 -11.64 -0.72 1.26e-21 Crohn's disease;Inflammatory bowel disease; TGCT cis rs3733585 0.699 rs57574512 chr4:9960182 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs67311347 1.000 rs9874499 chr3:40441908 C/T cg17264618 chr3:40429014 ENTPD3 0.33 4.73 0.39 5.89e-6 Renal cell carcinoma; TGCT cis rs68170813 0.641 rs74451547 chr7:107078435 A/C cg02696742 chr7:106810147 HBP1 -0.65 -5.15 -0.42 1.01e-6 Coronary artery disease; TGCT cis rs4665809 1.000 rs4665304 chr2:26313406 C/T cg25036284 chr2:26402008 FAM59B -0.56 -4.88 -0.4 3.2e-6 Gut microbiome composition (summer); TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg24846343 chr22:24311635 DDTL 0.25 6.26 0.49 5.83e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1538970 0.924 rs2088100 chr1:45877575 C/T cg05343316 chr1:45956843 TESK2 0.72 5.53 0.44 1.82e-7 Platelet count; TGCT cis rs9372253 1.000 rs9384740 chr6:110716207 G/A cg13266496 chr6:110720918 DDO -0.46 -5.68 -0.45 8.89e-8 Platelet distribution width; TGCT cis rs1008375 1.000 rs10011865 chr4:17645710 G/A cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6681544 0.544 rs6696876 chr1:82392040 C/T cg04226724 chr1:82268649 LPHN2 0.48 5.06 0.41 1.5e-6 Metabolite levels (X-11787); TGCT cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs694739 0.628 rs475032 chr11:64140737 G/C cg02228329 chr11:64053129 BAD;GPR137 -0.7 -6.8 -0.52 4.02e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs72945132 1.000 rs7938912 chr11:70114885 C/T cg00319359 chr11:70116639 PPFIA1 0.98 7.07 0.54 9.95e-11 Coronary artery disease; TGCT cis rs7666738 0.830 rs34313689 chr4:99013689 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs13126513 0.519 rs12641768 chr4:100558594 C/A cg05468953 chr4:100565104 NA 0.4 5.61 0.45 1.26e-7 Metabolite levels (MHPG); TGCT cis rs1552244 0.882 rs55962400 chr3:10044457 C/T cg00149659 chr3:10157352 C3orf10 0.79 4.96 0.41 2.27e-6 Alzheimer's disease; TGCT cis rs9486719 0.895 rs34051754 chr6:97007754 A/T cg06623918 chr6:96969491 KIAA0776 -1.01 -8.32 -0.6 1.32e-13 Migraine;Coronary artery disease; TGCT cis rs13064447 0.967 rs9861125 chr3:12765012 G/A cg20675869 chr3:12750130 NA -0.19 -4.67 -0.39 7.75e-6 Major depression and alcohol dependence; TGCT cis rs3785574 0.962 rs2584628 chr17:61894578 T/C cg06601766 chr17:61851465 DDX42;CCDC47 0.52 4.56 0.38 1.21e-5 Height; TGCT cis rs758747 0.531 rs8058233 chr16:3638809 G/A cg07396092 chr16:3662230 BTBD12 0.57 4.88 0.4 3.16e-6 Body mass index; TGCT cis rs10504229 0.906 rs7003276 chr8:58173089 A/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs9634489 0.502 rs431500 chr13:97102003 C/T cg11411106 chr13:97107445 HS6ST3 0.26 4.63 0.38 8.92e-6 Body mass index; TGCT cis rs4499344 0.633 rs259246 chr19:33146154 G/C cg26639809 chr19:33781782 NA 0.22 4.63 0.38 9.01e-6 Mean platelet volume; TGCT cis rs2239547 0.603 rs4687698 chr3:53097108 C/T cg10802521 chr3:52805072 NEK4 -0.57 -5.24 -0.43 6.68e-7 Schizophrenia; TGCT cis rs7666738 0.830 rs11938686 chr4:98964470 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.48 0.56 1.18e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1348850 0.632 rs13009207 chr2:178501632 A/G cg22681709 chr2:178499509 PDE11A -0.54 -6.63 -0.51 9.22e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs66561647 0.853 rs66824612 chr8:128967819 C/T cg05480350 chr8:128972681 MIR1205;PVT1 0.22 4.48 0.37 1.71e-5 Hemoglobin concentration; TGCT trans rs10504390 0.656 rs79616747 chr8:66546593 C/A cg26037026 chr7:1641922 NA -0.64 -6.84 -0.52 3.29e-10 IgG glycosylation; TGCT cis rs319204 0.761 rs319156 chr5:146304946 T/C cg25021259 chr5:146258546 PPP2R2B 0.39 4.69 0.39 7.23e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs10012003 chr4:99064881 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.37e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7727544 0.660 rs274563 chr5:131717859 C/A cg24060327 chr5:131705240 SLC22A5 0.61 6.7 0.52 6.54e-10 Blood metabolite levels; TGCT cis rs1580019 0.587 rs10951338 chr7:32560089 A/G cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.86 0.4 3.43e-6 Cognitive ability; TGCT cis rs9733 0.596 rs2175615 chr1:150624101 A/G cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg09177884 chr7:1199841 ZFAND2A -0.5 -4.68 -0.39 7.46e-6 Longevity;Endometriosis; TGCT cis rs7100689 0.556 rs6585971 chr10:82145057 G/C cg01528321 chr10:82214614 TSPAN14 0.78 7.86 0.58 1.56e-12 Post bronchodilator FEV1; TGCT cis rs259282 0.524 rs11878322 chr19:33122886 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.59 5.49 0.44 2.13e-7 Schizophrenia; TGCT cis rs2116941 1.000 rs7250265 chr19:10339818 G/C cg01850179 chr19:10340795 S1PR2 -0.75 -10.01 -0.67 1.21e-17 Pulse pressure; TGCT cis rs6076065 0.748 rs2295239 chr20:23387550 C/T cg11657817 chr20:23433608 CST11 0.31 5.42 0.44 3.02e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs9911578 0.934 rs58092632 chr17:57111101 T/C cg12560992 chr17:57184187 TRIM37 -0.79 -9.55 -0.65 1.52e-16 Intelligence (multi-trait analysis); TGCT cis rs2013441 0.901 rs2526474 chr17:20137134 C/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs7605378 1.000 rs2346662 chr2:200679158 C/T cg17644776 chr2:200775616 C2orf69 0.25 5.05 0.41 1.52e-6 Osteoporosis; TGCT cis rs2303745 0.622 rs1864113 chr19:17393504 G/C cg04248312 chr19:17393744 ANKLE1 -0.34 -5.7 -0.46 8.29e-8 Systemic lupus erythematosus; TGCT cis rs2075371 0.966 rs2544224 chr7:133995832 A/G cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs1023500 0.505 rs134887 chr22:42674239 A/G cg15557168 chr22:42548783 NA -0.21 -4.99 -0.41 2.03e-6 Schizophrenia; TGCT cis rs28595532 0.920 rs28797314 chr4:119783044 A/G cg00700008 chr4:120138107 USP53 0.49 4.48 0.37 1.71e-5 Cannabis dependence symptom count; TGCT cis rs9311474 0.652 rs614288 chr3:52220203 T/C cg10802521 chr3:52805072 NEK4 -0.56 -6.12 -0.48 1.11e-8 Electroencephalogram traits; TGCT cis rs7412746 0.658 rs7526489 chr1:150726238 C/T cg09365446 chr1:150670422 GOLPH3L 0.33 4.78 0.39 4.8e-6 Melanoma; TGCT cis rs2439831 0.850 rs12702 chr15:44093927 C/T cg02155558 chr15:43621948 ADAL;LCMT2 -0.71 -5.48 -0.44 2.29e-7 Lung cancer in ever smokers; TGCT cis rs875971 0.895 rs4718349 chr7:65909011 C/G cg11764359 chr7:65958608 NA 0.59 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs12210905 1.000 rs9393803 chr6:27257714 A/G cg08851530 chr6:28072375 NA 1.29 5.49 0.44 2.19e-7 Hip circumference adjusted for BMI; TGCT cis rs7681440 0.933 rs10005233 chr4:90743331 C/T cg14346243 chr4:90757452 SNCA -0.57 -5.55 -0.45 1.66e-7 Dementia with Lewy bodies; TGCT cis rs1403694 0.515 rs1656925 chr3:186449123 T/C cg12454167 chr3:186435060 KNG1 0.46 7.19 0.54 5.47e-11 Blood protein levels; TGCT cis rs151997 0.925 rs26087 chr5:50172911 G/A cg06027927 chr5:50259733 NA 0.46 4.63 0.38 9.01e-6 Callous-unemotional behaviour; TGCT cis rs7126328 1 rs7126328 chr11:120244577 C/T cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.62 -0.38 9.51e-6 Intraocular pressure; TGCT cis rs986417 1.000 rs1950904 chr14:60964954 G/C cg27398547 chr14:60952738 C14orf39 1.49 10.81 0.7 1.38e-19 Gut microbiota (bacterial taxa); TGCT cis rs9972944 0.756 rs9907996 chr17:63754889 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.09 -0.42 1.27e-6 Total body bone mineral density; TGCT cis rs7772486 0.754 rs9386134 chr6:146145508 G/A cg23711669 chr6:146136114 FBXO30 0.94 10.97 0.7 5.5e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs57590327 0.503 rs12497231 chr3:81519291 A/G cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs11711311 0.955 rs34458493 chr3:113396473 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -6.88 -0.53 2.6200000000000003e-10 IgG glycosylation; TGCT cis rs752010 0.806 rs11210500 chr1:42089737 A/G cg06885757 chr1:42089581 HIVEP3 0.25 4.56 0.38 1.23e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg09222892 chr1:25734099 RHCE 0.44 7.13 0.54 7.46e-11 Erythrocyte sedimentation rate; TGCT cis rs6427508 1 rs6427508 chr1:160238857 T/C cg07195126 chr1:160370843 VANGL2 0.51 4.67 0.39 7.58e-6 Breast size; TGCT cis rs769267 0.930 rs892021 chr19:19613480 T/C cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs9303401 0.527 rs34835800 chr17:56764990 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.53 5.05 0.41 1.55e-6 Cognitive test performance; TGCT cis rs8020441 0.786 rs59498790 chr14:51167929 T/A cg04730355 chr14:51134070 SAV1 0.75 6.1 0.48 1.25e-8 Cognitive performance; TGCT cis rs9291683 0.546 rs4575994 chr4:9997979 G/A cg00071950 chr4:10020882 SLC2A9 0.6 6.77 0.52 4.6e-10 Bone mineral density; TGCT cis rs7267979 0.586 rs1473695 chr20:25186965 A/G cg14121845 chr20:25566513 NINL 0.45 4.86 0.4 3.51e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12682352 0.652 rs1567398 chr8:8726804 A/C cg08975724 chr8:8085496 FLJ10661 -0.6 -5.76 -0.46 6.15e-8 Neuroticism; TGCT cis rs9796 0.621 rs28737302 chr15:41469943 G/A cg18705301 chr15:41695430 NDUFAF1 -0.52 -7.17 -0.54 5.94e-11 Menopause (age at onset); TGCT cis rs7267979 0.933 rs11699203 chr20:25435169 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3806843 0.576 rs246024 chr5:140333952 C/T cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs13082711 0.522 rs7651661 chr3:27362773 G/C cg02860705 chr3:27208620 NA 0.29 4.85 0.4 3.67e-6 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7412746 0.658 rs6660845 chr1:150841066 G/A cg09365446 chr1:150670422 GOLPH3L 0.35 4.98 0.41 2.11e-6 Melanoma; TGCT cis rs13064447 0.817 rs73022951 chr3:12767557 G/A cg20675869 chr3:12750130 NA -0.2 -5.03 -0.41 1.65e-6 Major depression and alcohol dependence; TGCT cis rs7178572 0.568 rs1565757 chr15:77657682 C/T cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs9611565 0.659 rs17367849 chr22:41923644 G/A cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs28595532 0.920 rs115214765 chr4:119728167 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs1372520 0.684 rs2583968 chr4:90745395 C/G cg20003494 chr4:90757398 SNCA -0.63 -5.06 -0.41 1.48e-6 Neuroticism; TGCT cis rs986417 0.748 rs4400969 chr14:61013298 A/C cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs644799 1.000 rs557079 chr11:95530125 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9549260 0.755 rs2755214 chr13:41149345 T/G cg21288729 chr13:41239152 FOXO1 1.0 10.34 0.68 1.84e-18 Red blood cell count; TGCT cis rs7611238 0.560 rs7641810 chr3:195055633 G/C cg27323046 chr3:195102265 ACAP2 0.35 4.75 0.39 5.5e-6 Body mass index; TGCT cis rs1371867 0.875 rs1660319 chr8:101337530 A/G cg06002616 chr8:101225028 SPAG1 -0.54 -6.29 -0.49 4.88e-9 Atrioventricular conduction; TGCT cis rs9926296 0.632 rs1800286 chr16:89869761 T/C cg03388025 chr16:89894329 SPIRE2 0.34 4.67 0.39 7.57e-6 Vitiligo; TGCT cis rs12220238 0.915 rs10824197 chr10:76282793 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.89 5.7 0.46 8.36e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg03188948 chr7:1209495 NA 0.42 5.65 0.45 1.03e-7 Longevity;Endometriosis; TGCT cis rs28595532 0.920 rs115673173 chr4:119755321 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs514406 0.825 rs9661082 chr1:53245472 A/T cg16325326 chr1:53192061 ZYG11B -0.71 -8.81 -0.62 9.22e-15 Monocyte count; TGCT cis rs9921338 0.961 rs11074958 chr16:11397079 C/T cg00044050 chr16:11439710 C16orf75 -0.97 -7.1 -0.54 8.61e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs2235642 0.859 rs12599207 chr16:1606445 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.3 -4.93 -0.41 2.53e-6 Coronary artery disease; TGCT cis rs35306767 0.903 rs11253494 chr10:937047 C/T cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs6951245 0.748 rs79658522 chr7:1095877 A/G cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7959452 0.590 rs10878974 chr12:69781528 C/G cg20891283 chr12:69753455 YEATS4 0.83 8.7 0.62 1.68e-14 Blood protein levels; TGCT cis rs6835098 0.539 rs1383628 chr4:174194453 C/T cg08422745 chr4:174089978 GALNT7 -0.59 -5.97 -0.47 2.31e-8 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs6977660 0.714 rs10276518 chr7:19781325 C/A cg07541023 chr7:19748670 TWISTNB 0.87 4.92 0.4 2.74e-6 Thyroid stimulating hormone; TGCT cis rs28374715 0.617 rs16971733 chr15:41562030 C/A cg18705301 chr15:41695430 NDUFAF1 -0.65 -8.7 -0.62 1.71e-14 Ulcerative colitis; TGCT cis rs2658782 0.593 rs2243410 chr11:93255519 T/G cg15737290 chr11:93063684 CCDC67 0.63 4.71 0.39 6.59e-6 Pulmonary function decline; TGCT cis rs7666738 0.515 rs28615369 chr4:98896858 C/T cg05340658 chr4:99064831 C4orf37 0.56 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7010267 0.935 rs6415470 chr8:119955111 G/A cg17171407 chr8:119960777 TNFRSF11B 0.33 6.18 0.49 8.29e-9 Total body bone mineral density (age 45-60); TGCT cis rs2688608 0.839 rs2633311 chr10:75598099 C/T cg19442545 chr10:75533431 FUT11 0.31 4.53 0.38 1.35e-5 Inflammatory bowel disease; TGCT cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs907683 0.559 rs11685408 chr2:220291474 T/C cg15015639 chr2:220282977 DES 0.4 5.11 0.42 1.18e-6 Resting heart rate; TGCT cis rs763014 0.966 rs4144003 chr16:645968 C/T cg09263875 chr16:632152 PIGQ 0.31 6.91 0.53 2.22e-10 Height; TGCT cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg04267008 chr7:1944627 MAD1L1 -0.41 -5.45 -0.44 2.65e-7 Bipolar disorder and schizophrenia; TGCT cis rs7465272 0.530 rs10103161 chr8:143738571 A/G cg24634471 chr8:143751801 JRK 0.56 5.58 0.45 1.46e-7 Bipolar disorder and schizophrenia; TGCT cis rs67311347 0.502 rs3924444 chr3:40576061 T/C cg13683864 chr3:40499215 RPL14 -0.64 -5.89 -0.47 3.44e-8 Renal cell carcinoma; TGCT cis rs763014 0.966 rs4144003 chr16:645968 C/T cg07343612 chr16:622815 PIGQ -0.41 -8.1 -0.59 4.34e-13 Height; TGCT cis rs2456568 0.835 rs1518578 chr11:93656854 G/T cg14065697 chr11:93583672 C11orf90 -0.39 -4.63 -0.38 9.22e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6665290 0.904 rs6664955 chr1:227183434 T/C cg10327440 chr1:227177885 CDC42BPA -0.98 -19.78 -0.87 3.72e-40 Myeloid white cell count; TGCT cis rs3818285 1.000 rs10787218 chr10:111621456 A/C cg00817464 chr10:111662876 XPNPEP1 -0.29 -4.5 -0.37 1.53e-5 Superior crus of antihelix expression; TGCT cis rs79349575 0.749 rs1057902 chr17:47005588 C/T cg07967210 chr17:47022446 SNF8 0.44 6.09 0.48 1.33e-8 Type 2 diabetes; TGCT cis rs2952156 0.684 rs11658786 chr17:37815899 G/A cg00129232 chr17:37814104 STARD3 -0.22 -4.48 -0.37 1.68e-5 Asthma; TGCT cis rs951366 0.903 rs823114 chr1:205719532 G/A cg17178900 chr1:205818956 PM20D1 0.41 4.56 0.38 1.19e-5 Menarche (age at onset); TGCT cis rs11250098 0.567 rs4326350 chr8:10763655 C/G cg21775007 chr8:11205619 TDH 0.49 4.52 0.38 1.44e-5 Morning vs. evening chronotype; TGCT cis rs2456568 0.741 rs9633811 chr11:93628327 A/G cg14065697 chr11:93583672 C11orf90 0.38 4.82 0.4 4.06e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2019137 0.560 rs7578633 chr2:113978650 C/T cg09704166 chr2:114031854 PAX8;LOC440839 -0.34 -4.96 -0.41 2.29e-6 Lymphocyte counts; TGCT cis rs6964587 0.626 rs2188841 chr7:91522641 A/G cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs6500602 0.964 rs2896893 chr16:4478559 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.09 0.42 1.28e-6 Schizophrenia; TGCT cis rs12711979 0.509 rs10195596 chr2:3824222 T/G cg17052675 chr2:3827356 NA -0.55 -12.72 -0.75 3.04e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs8180040 0.701 rs12491473 chr3:46989904 G/A cg27129171 chr3:47204927 SETD2 -0.71 -8.9 -0.62 5.58e-15 Colorectal cancer; TGCT cis rs13108904 0.901 rs6826029 chr4:1307689 A/G cg03303774 chr4:1407052 NA 0.32 4.74 0.39 5.74e-6 Obesity-related traits; TGCT cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg08975724 chr8:8085496 FLJ10661 0.58 5.22 0.42 7.33e-7 Systolic blood pressure; TGCT cis rs4851313 0.527 rs10183150 chr2:100939117 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.92 -0.4 2.7e-6 Intelligence (multi-trait analysis); TGCT cis rs2688608 0.592 rs7908825 chr10:75554541 C/G cg19442545 chr10:75533431 FUT11 0.36 5.7 0.46 8.36e-8 Inflammatory bowel disease; TGCT cis rs13191362 0.507 rs2510207 chr6:163086592 T/C cg21926612 chr6:163149169 PACRG;PARK2 -0.66 -5.89 -0.47 3.46e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs554111 0.656 rs17450813 chr1:21264308 T/C cg01072550 chr1:21505969 NA 0.35 5.33 0.43 4.38e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs709400 1.000 rs55885592 chr14:104126024 C/T cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs9948 0.786 rs62152774 chr2:97448377 A/G cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs10504229 0.817 rs55891651 chr8:58167600 C/T cg08280861 chr8:58055591 NA 0.32 4.46 0.37 1.83e-5 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs13030858 chr2:26315451 G/A cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs6993813 0.590 rs10955919 chr8:120020918 C/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs422249 0.511 rs102274 chr11:61557826 T/C cg19610905 chr11:61596333 FADS2 -1.04 -10.88 -0.7 8.91e-20 Trans fatty acid levels; TGCT cis rs2013441 1.000 rs2165897 chr17:20209721 T/C cg23224458 chr17:20280056 CCDC144C -0.41 -4.88 -0.4 3.25e-6 Obesity-related traits; TGCT cis rs6714710 0.580 rs35564270 chr2:98602165 A/G cg26665480 chr2:98280029 ACTR1B 0.63 6.01 0.47 1.92e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2201841 0.960 rs10889676 chr1:67722567 C/A cg25131922 chr1:68698529 GPR177 0.43 4.58 0.38 1.1e-5 Ulcerative colitis;Psoriasis;Crohn's disease; TGCT cis rs3087591 0.573 rs731758 chr17:29723000 C/G cg24425628 chr17:29625626 OMG;NF1 0.37 5.36 0.43 3.96e-7 Hip circumference; TGCT cis rs9611565 0.659 rs12484228 chr22:41939739 A/G cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs12220898 0.748 rs10776550 chr10:50472901 A/G cg06072769 chr10:50146962 WDFY4 0.35 4.63 0.38 9.25e-6 Inflammatory biomarkers; TGCT cis rs7000551 0.689 rs10110254 chr8:22309551 G/T cg12081754 chr8:22256438 SLC39A14 0.3 4.93 0.4 2.55e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg18402987 chr7:1209562 NA 0.39 5.03 0.41 1.64e-6 Longevity;Endometriosis; TGCT cis rs9868809 0.656 rs73078362 chr3:48703917 G/C cg00383909 chr3:49044727 WDR6 1.3 6.21 0.49 7.36e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs12142240 0.667 rs12062 chr1:46830447 G/T cg00530320 chr1:46809349 NSUN4 -0.3 -6.22 -0.49 7.07e-9 Menopause (age at onset); TGCT cis rs7474896 0.583 rs34185758 chr10:37990854 T/C cg25427524 chr10:38739819 LOC399744 -0.33 -4.99 -0.41 2.03e-6 Obesity (extreme); TGCT cis rs8081692 1 rs8081692 chr17:38154595 A/G cg17467752 chr17:38218738 THRA 0.54 5.17 0.42 8.96e-7 Neutrophil count; TGCT cis rs3091242 0.806 rs35189848 chr1:25788422 A/G cg10117171 chr1:25599238 RHD 0.32 5.16 0.42 9.43e-7 Erythrocyte sedimentation rate; TGCT cis rs425277 1.000 rs262647 chr1:2095699 C/T cg24578937 chr1:2090814 PRKCZ 0.32 8.19 0.59 2.64e-13 Height; TGCT trans rs62103177 0.733 rs62103193 chr18:77629217 C/T cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs4638749 1.000 rs10209928 chr2:108863898 C/T cg06795125 chr2:108905320 SULT1C2 -0.37 -4.69 -0.39 6.95e-6 Blood pressure; TGCT cis rs10504229 0.520 rs55967509 chr8:57992448 A/G cg08280861 chr8:58055591 NA 0.34 4.69 0.39 7.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs977747 0.872 rs743270 chr1:47675536 G/C cg03885399 chr1:47691550 TAL1 -0.42 -5.48 -0.44 2.26e-7 Body mass index; TGCT cis rs11203032 0.831 rs2211599 chr10:90929547 G/A cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs7666738 0.677 rs13120306 chr4:99036099 A/T cg18180107 chr4:99064573 C4orf37 0.59 5.37 0.43 3.73e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7809950 0.817 rs2712224 chr7:107181235 C/A cg23024343 chr7:107201750 COG5 -0.48 -6.95 -0.53 1.82e-10 Coronary artery disease; TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs7647973 0.626 rs11720705 chr3:49753788 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs17681684 0.565 rs12150476 chr17:9763876 A/C cg15743799 chr17:9805578 RCVRN -0.27 -5.89 -0.47 3.45e-8 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs2153535 0.580 rs9379206 chr6:8458021 C/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs9921338 0.924 rs7204628 chr16:11444572 A/C cg00044050 chr16:11439710 C16orf75 -0.89 -6.8 -0.52 3.88e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs11690935 0.959 rs12185567 chr2:172560729 A/C cg13550731 chr2:172543902 DYNC1I2 1.21 13.07 0.76 4.43e-25 Schizophrenia; TGCT cis rs1348850 0.632 rs12467363 chr2:178502512 C/T cg22681709 chr2:178499509 PDE11A -0.53 -6.64 -0.51 8.93e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs28785552 0.589 rs7257371 chr19:53243910 A/G cg04754360 chr19:53238445 ZNF611 -0.61 -4.86 -0.4 3.52e-6 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs74054849 0.850 rs41270277 chr1:15960364 G/A cg05660106 chr1:15850417 CASP9 0.86 4.48 0.37 1.68e-5 Alcoholic chronic pancreatitis; TGCT cis rs7940866 0.770 rs10750456 chr11:130819634 A/G cg05962950 chr11:130786565 SNX19 0.74 7.27 0.55 3.54e-11 Schizophrenia; TGCT cis rs148387471 1 rs148387471 chr3:127057551 ATAG/A cg25436886 chr3:127056972 NA -0.53 -4.86 -0.4 3.51e-6 Interleukin-10 levels;Interleukin-13 levels; TGCT cis rs6674176 0.628 rs2240447 chr1:44415415 C/T cg12908607 chr1:44402522 ARTN -0.68 -8.19 -0.59 2.7e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7599312 0.534 rs10182996 chr2:213404834 T/C cg20637307 chr2:213403960 ERBB4 0.91 11.8 0.73 5.21e-22 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6770219 0.516 rs6444126 chr3:186138608 T/C cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs6671200 0.915 rs34266846 chr1:95739748 G/A cg03123541 chr1:95699097 RWDD3 1.0 6.44 0.5 2.43e-9 Stearic acid (18:0) levels; TGCT cis rs10992471 0.651 rs10124058 chr9:95522882 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.48 -0.44 2.27e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs16866061 1.000 rs72974238 chr2:225432470 C/A cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs1799949 0.965 rs34633610 chr17:41419385 A/G cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs9858542 0.953 rs11710037 chr3:49675334 C/G cg03060546 chr3:49711283 APEH -0.64 -5.7 -0.46 8.18e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs13108904 0.905 rs11247983 chr4:1281951 C/G cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs11190604 1.000 rs7079136 chr10:102292709 T/C cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs916888 0.773 rs199443 chr17:44819565 C/T cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.8 5.52 0.44 1.89e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7208859 0.573 rs55661352 chr17:29045628 A/G cg13385521 chr17:29058706 SUZ12P 0.79 4.75 0.39 5.57e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2404602 0.692 rs58889902 chr15:77173070 A/C cg26408565 chr15:76604113 ETFA -0.36 -4.52 -0.38 1.41e-5 Blood metabolite levels; TGCT cis rs2836950 0.565 rs3171465 chr21:40552307 A/G cg17971929 chr21:40555470 PSMG1 -0.52 -4.57 -0.38 1.18e-5 Menarche (age at onset); TGCT cis rs6951245 0.507 rs11976805 chr7:1138716 C/T cg23708337 chr7:1209742 NA 0.43 4.96 0.41 2.23e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7267979 1.000 rs6037086 chr20:25306338 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs858239 0.600 rs13438179 chr7:23143851 T/C cg05602783 chr7:23145260 KLHL7 -0.68 -5.75 -0.46 6.69e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs9486719 0.857 rs3798293 chr6:97033370 A/G cg18709589 chr6:96969512 KIAA0776 -0.75 -5.88 -0.47 3.64e-8 Migraine;Coronary artery disease; TGCT cis rs10883723 0.810 rs7094751 chr10:104274818 G/A cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT trans rs208520 0.526 rs9294682 chr6:66795159 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.09 -16.9 -0.84 5.6e-34 Exhaled nitric oxide output; TGCT cis rs7267979 1.000 rs6115191 chr20:25440478 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs600231 0.706 rs10896016 chr11:65335705 C/T cg21890820 chr11:65308645 LTBP3 -0.37 -4.9 -0.4 2.91e-6 Bone mineral density; TGCT cis rs346785 0.692 rs4789273 chr17:74286082 A/G cg09812376 chr17:74270190 QRICH2 0.32 4.99 0.41 1.99e-6 White matter hyperintensities in ischemic stroke; TGCT cis rs2456568 0.548 rs4402256 chr11:93660803 T/C cg26875233 chr11:93583750 C11orf90 -0.43 -5.4 -0.44 3.25e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9911578 1.000 rs304296 chr17:56834229 G/T cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs7809950 1.000 rs987391 chr7:107100794 C/G cg23024343 chr7:107201750 COG5 -0.34 -5.43 -0.44 2.92e-7 Coronary artery disease; TGCT cis rs6840360 0.530 rs11946622 chr4:152486018 C/T cg17479576 chr4:152424074 FAM160A1 -0.68 -7.3 -0.55 3.07e-11 Intelligence (multi-trait analysis); TGCT cis rs789859 0.869 rs1773225 chr3:194403578 A/G cg21106136 chr3:194405973 FAM43A -0.39 -5.72 -0.46 7.55e-8 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs2688608 0.592 rs11814282 chr10:75490217 T/C cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs6540559 1.000 rs17015259 chr1:209982923 G/A cg21951975 chr1:209979733 IRF6 0.7 6.01 0.47 1.92e-8 Cleft lip with or without cleft palate; TGCT cis rs7017914 0.934 rs7830550 chr8:71570431 C/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.49 -4.57 -0.38 1.17e-5 Bone mineral density; TGCT cis rs477895 0.713 rs12575642 chr11:63979643 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.79 6.65 0.51 8.31e-10 Mean platelet volume; TGCT cis rs12908161 1.000 rs60957376 chr15:85280792 T/G cg12863693 chr15:85201151 NMB 0.42 4.99 0.41 2.03e-6 Schizophrenia; TGCT cis rs4372836 0.504 rs7601720 chr2:29032478 G/A cg09522027 chr2:28974177 PPP1CB -0.55 -5.59 -0.45 1.34e-7 Body mass index; TGCT trans rs1005277 0.579 rs1740747 chr10:38520465 G/A cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7666738 0.830 rs969048 chr4:98988921 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 1.000 rs10865956 chr3:49581559 C/A cg05785598 chr3:49045655 WDR6 0.38 4.6 0.38 1.02e-5 Menarche (age at onset); TGCT cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.63 -6.23 -0.49 6.56e-9 Bipolar disorder; TGCT cis rs1008375 1.000 rs6449323 chr4:17683916 A/T cg16339924 chr4:17578868 LAP3 0.54 4.5 0.37 1.55e-5 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13256369 0.851 rs13256611 chr8:8564341 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs877282 0.853 rs7069720 chr10:754487 A/G cg17470449 chr10:769945 NA 0.32 4.91 0.4 2.76e-6 Uric acid levels; TGCT cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg06634786 chr22:41940651 POLR3H -0.89 -8.27 -0.6 1.71e-13 Vitiligo; TGCT cis rs7394190 0.748 rs3843939 chr10:75578948 T/C cg07699608 chr10:75541558 CHCHD1 0.79 4.95 0.41 2.42e-6 Incident atrial fibrillation; TGCT cis rs597539 0.652 rs686877 chr11:68637169 G/A cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6918586 0.658 rs198826 chr6:26121153 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.68 6.46 0.5 2.18e-9 Schizophrenia; TGCT cis rs78487399 0.808 rs78108161 chr2:43663848 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.27 -0.43 5.74e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs1129187 0.755 rs9462855 chr6:42925936 G/C cg10862848 chr6:42927986 GNMT -0.39 -4.7 -0.39 6.86e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9467711 1.000 rs6908156 chr6:26322861 C/T cg26531700 chr6:26746687 NA -0.94 -5.09 -0.42 1.28e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs826838 1.000 rs11183160 chr12:38676702 T/C cg13010199 chr12:38710504 ALG10B 0.78 6.16 0.48 9.25e-9 Heart rate; TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg26338869 chr17:61819248 STRADA -0.55 -5.03 -0.41 1.65e-6 Prudent dietary pattern; TGCT trans rs7819412 0.805 rs2409710 chr8:10979821 A/G cg06636001 chr8:8085503 FLJ10661 -0.75 -7.16 -0.54 6.28e-11 Triglycerides; TGCT cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9894429 0.690 rs12949956 chr17:79542813 C/T cg21984481 chr17:79567631 NPLOC4 0.26 4.83 0.4 3.98e-6 Eye color traits; TGCT cis rs4819052 1.000 rs13047688 chr21:46669290 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.91 7.43 0.55 1.55e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2334880 0.641 rs12325234 chr16:71459628 A/T cg06353428 chr16:71660113 MARVELD3 -1.14 -7.12 -0.54 7.54e-11 Malaria; TGCT cis rs916888 0.779 rs430685 chr17:44859148 T/C cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4563143 0.577 rs73025093 chr19:29254618 T/G cg03161606 chr19:29218774 NA 0.59 5.69 0.45 8.74e-8 Methadone dose in opioid dependence; TGCT cis rs13217239 0.646 rs11756275 chr6:27007113 A/C cg15659132 chr6:26577336 NA -0.52 -5.16 -0.42 9.5e-7 Schizophrenia; TGCT cis rs8017423 1.000 rs8017423 chr14:90679910 A/G cg04374321 chr14:90722782 PSMC1 0.74 7.67 0.57 4.41e-12 Mortality in heart failure; TGCT cis rs3847687 1.000 rs10848269 chr12:131518622 A/G cg25772418 chr12:131519998 GPR133 -0.31 -5.51 -0.44 1.95e-7 Longevity; TGCT cis rs10883723 0.810 rs7069356 chr10:104254359 G/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2836974 0.565 rs34304022 chr21:40579619 G/A cg17971929 chr21:40555470 PSMG1 0.67 4.59 0.38 1.06e-5 Cognitive function; TGCT cis rs9913156 0.670 rs9894225 chr17:4546559 A/G cg19197139 chr17:4613644 ARRB2 -0.8 -7.68 -0.57 4.19e-12 Lymphocyte counts; TGCT cis rs9300255 0.602 rs2682431 chr12:123703226 T/A cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs2228479 0.764 rs35518096 chr16:89961140 C/A cg06558623 chr16:89946397 TCF25 0.5 6.04 0.48 1.68e-8 Skin colour saturation; TGCT cis rs1552244 0.938 rs9873794 chr3:10074153 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.59 0.45 1.39e-7 Alzheimer's disease; TGCT cis rs9393692 1.000 rs3999544 chr6:26285867 C/T cg13736514 chr6:26305472 NA -0.43 -6.28 -0.49 5.32e-9 Educational attainment; TGCT cis rs11098499 0.863 rs6853998 chr4:120475860 C/A cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs10782582 0.609 rs1630587 chr1:76399787 T/C cg22875332 chr1:76189707 ACADM -0.45 -4.53 -0.38 1.34e-5 Daytime sleep phenotypes; TGCT cis rs7582180 0.629 rs13004216 chr2:100945402 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs710216 0.957 rs12041787 chr1:43432275 G/C cg03128534 chr1:43423976 SLC2A1 0.6 4.6 0.38 1.01e-5 Red cell distribution width; TGCT cis rs4478037 0.822 rs3924695 chr3:33122085 C/T cg19404215 chr3:33155277 CRTAP 1.03 5.38 0.44 3.56e-7 Major depressive disorder; TGCT cis rs16958440 0.867 rs79395141 chr18:44695680 A/G cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs2996428 0.629 rs12135894 chr1:3728061 C/T cg17848003 chr1:3704513 LRRC47 0.17 4.63 0.38 9.05e-6 Red cell distribution width; TGCT cis rs2836950 0.565 rs2836934 chr21:40564885 A/C cg06238570 chr21:40685208 BRWD1 -0.62 -6.55 -0.51 1.4e-9 Menarche (age at onset); TGCT cis rs7666738 0.791 rs11097610 chr4:99011795 C/G cg05340658 chr4:99064831 C4orf37 0.47 5.23 0.43 6.96e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 0.738 rs41293275 chr1:46806429 A/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.78 -0.39 4.78e-6 Menopause (age at onset); TGCT cis rs941408 1.000 rs759068 chr19:2792566 G/A cg06609049 chr19:2785107 THOP1 0.8 7.95 0.58 9.77e-13 Total cholesterol levels; TGCT cis rs9674544 0.646 rs6504594 chr17:47142697 C/A cg07075026 chr17:47091521 IGF2BP1 -0.41 -4.57 -0.38 1.18e-5 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs2580764 0.565 rs2044291 chr2:55247954 A/G cg09592903 chr2:55203963 RTN4 -0.27 -6.05 -0.48 1.59e-8 Mean platelet volume; TGCT cis rs858239 0.899 rs2268745 chr7:23317600 G/A cg05602783 chr7:23145260 KLHL7 -0.66 -5.31 -0.43 4.92e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs7246657 0.525 rs10410594 chr19:37477758 C/T cg18154014 chr19:37997991 ZNF793 0.73 4.58 0.38 1.11e-5 Coronary artery calcification; TGCT cis rs4886920 0.563 rs4442775 chr15:78079120 T/C cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs2153535 0.580 rs5001130 chr6:8442298 G/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs10089 0.953 rs6875982 chr5:127529197 A/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.79 7.54 0.56 8.56e-12 Ileal carcinoids; TGCT cis rs1552244 0.572 rs3843008 chr3:10173742 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.42 -5.11 -0.42 1.16e-6 Alzheimer's disease; TGCT cis rs2032447 0.714 rs129129 chr6:25961029 A/G cg03517284 chr6:25882590 NA -0.63 -5.77 -0.46 5.91e-8 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.728 rs17804774 chr8:58155950 G/T cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs9633740 1.000 rs7922621 chr10:82251544 C/A cg01528321 chr10:82214614 TSPAN14 1.0 8.33 0.6 1.25e-13 Post bronchodilator FEV1; TGCT cis rs631288 0.557 rs894470 chr1:146671947 A/G cg25205988 chr1:146714368 CHD1L 1.33 5.42 0.44 2.97e-7 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs77633900 0.614 rs2459360 chr15:76868664 C/T cg21673338 chr15:77095150 SCAPER -0.51 -4.81 -0.4 4.22e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs6840360 0.593 rs11723227 chr4:152689717 G/A cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.62e-8 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.877 rs10057605 chr5:93443950 T/G cg25358565 chr5:93447407 FAM172A 0.93 8.37 0.6 1.04e-13 Diabetic retinopathy; TGCT cis rs11514810 1.000 rs57444112 chr7:1430892 T/C cg24899294 chr7:1481343 MICALL2 -0.47 -5.84 -0.46 4.24e-8 Executive inhibition (Stroop WIT and CIT) in attention deficit hyperactivity disorder; TGCT cis rs7568458 0.840 rs2886722 chr2:85742297 C/T cg17127132 chr2:85788382 GGCX -0.66 -6.12 -0.48 1.14e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs8051431 0.544 rs2878492 chr16:71981113 A/T cg06353428 chr16:71660113 MARVELD3 0.75 6.74 0.52 5.43e-10 LDL cholesterol levels; TGCT cis rs11874712 1.000 rs3765636 chr18:43653660 G/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.54 5.28 0.43 5.47e-7 Migraine - clinic-based; TGCT trans rs916888 0.647 rs199449 chr17:44808902 G/A cg01341218 chr17:43662625 NA 0.86 7.52 0.56 9.73e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4746818 1.000 rs10998614 chr10:70923347 G/T cg04149295 chr10:70884716 VPS26A 0.79 5.44 0.44 2.79e-7 Left atrial antero-posterior diameter; TGCT cis rs28595532 0.920 rs114314373 chr4:119639128 G/A cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.12e-11 Cannabis dependence symptom count; TGCT cis rs2688608 0.617 rs6480709 chr10:75479125 T/C cg23231163 chr10:75533350 FUT11 -0.29 -4.87 -0.4 3.37e-6 Inflammatory bowel disease; TGCT cis rs4478858 0.743 rs11578422 chr1:31707298 C/T cg00250761 chr1:31883323 NA -0.3 -5.42 -0.44 2.94e-7 Alcohol dependence; TGCT cis rs11864453 0.679 rs2303285 chr16:72124495 A/C cg14768367 chr16:72042858 DHODH 0.52 5.21 0.42 7.61e-7 Fibrinogen levels; TGCT cis rs1799949 1.000 rs12951869 chr17:41187567 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.0 0.41 1.89e-6 Menopause (age at onset); TGCT cis rs2836974 0.897 rs11911112 chr21:40528346 A/C cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs1801251 1.000 rs13004406 chr2:233584557 A/T cg25237894 chr2:233734115 C2orf82 -0.31 -5.52 -0.44 1.93e-7 Coronary artery disease; TGCT trans rs9388451 0.626 rs1935983 chr6:126068914 C/T cg05039488 chr6:79577232 IRAK1BP1 -0.87 -9.71 -0.66 6.39e-17 Brugada syndrome; TGCT cis rs3008870 1.000 rs4655663 chr1:67430103 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.07 10.99 0.7 5.04e-20 Lymphocyte percentage of white cells; TGCT cis rs9300255 0.739 rs1969354 chr12:123741776 T/C cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs1800682 0.528 rs3903454 chr10:90743434 A/T cg03111039 chr10:90751583 FAS;ACTA2 0.62 8.76 0.62 1.23e-14 Chronic lymphocytic leukemia; TGCT cis rs11167764 1.000 rs7722567 chr5:141483178 C/T cg02659431 chr5:141694439 SPRY4 -0.22 -4.72 -0.39 6.33e-6 Crohn's disease; TGCT cis rs12413816 0.517 rs4750400 chr10:13765923 A/G cg16485048 chr10:13749193 FRMD4A 0.23 4.59 0.38 1.07e-5 Red cell distribution width; TGCT cis rs2456568 0.503 rs11020603 chr11:93667439 A/G cg17595323 chr11:93583763 C11orf90 0.47 5.91 0.47 3.08e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10876993 0.890 rs10783844 chr12:58098425 A/C cg15848620 chr12:58087721 OS9 -0.72 -5.98 -0.47 2.25e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs2070488 0.775 rs7649984 chr3:38570221 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.64 -5.68 -0.45 9.01e-8 Electrocardiographic conduction measures; TGCT cis rs2549003 1.000 rs9282761 chr5:131822224 T/C cg21138405 chr5:131827807 IRF1 0.19 4.79 0.39 4.76e-6 Asthma (sex interaction); TGCT cis rs7216064 1.000 rs8082512 chr17:65837059 T/C cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs67311347 1.000 rs9860162 chr3:40403875 C/T cg17264618 chr3:40429014 ENTPD3 0.31 4.59 0.38 1.09e-5 Renal cell carcinoma; TGCT cis rs7819412 0.715 rs35223712 chr8:11043926 C/T cg21775007 chr8:11205619 TDH -0.51 -4.65 -0.39 8.35e-6 Triglycerides; TGCT cis rs240764 0.794 rs4840133 chr6:100914717 C/T cg21058520 chr6:100914733 NA 0.39 4.73 0.39 5.93e-6 Neuroticism; TGCT cis rs2404602 0.735 rs11637490 chr15:76759565 A/G cg22467129 chr15:76604101 ETFA 0.48 5.06 0.41 1.5e-6 Blood metabolite levels; TGCT cis rs9910055 0.718 rs2526022 chr17:42213216 C/T cg13607699 chr17:42295918 UBTF 0.84 7.76 0.57 2.72e-12 Total body bone mineral density; TGCT cis rs9322193 0.923 rs2185352 chr6:150035776 T/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs8073060 0.521 rs225254 chr17:33953384 G/A cg05299278 chr17:33885742 SLFN14 0.23 5.09 0.42 1.28e-6 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs3820068 0.608 rs9660255 chr1:16031891 T/G cg05660106 chr1:15850417 CASP9 0.64 5.99 0.47 2.09e-8 Systolic blood pressure; TGCT cis rs35146811 0.844 rs2070215 chr7:99696797 T/C cg13334819 chr7:99746414 C7orf59 -0.76 -6.38 -0.5 3.17e-9 Coronary artery disease; TGCT cis rs9653442 0.527 rs10176782 chr2:100782827 C/A cg22139774 chr2:100720529 AFF3 -0.36 -5.69 -0.46 8.67e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10193935 0.901 rs17029344 chr2:42444287 T/C cg27598129 chr2:42591480 NA -0.39 -5.16 -0.42 9.46e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3091242 0.867 rs602052 chr1:25722206 T/C cg10117171 chr1:25599238 RHD -0.36 -5.72 -0.46 7.56e-8 Erythrocyte sedimentation rate; TGCT cis rs56104184 0.775 rs55756106 chr19:49403055 A/G cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs8014204 0.587 rs6574201 chr14:75387256 T/C cg06637938 chr14:75390232 RPS6KL1 -0.9 -9.51 -0.65 1.92e-16 Caffeine consumption; TGCT cis rs3806843 0.771 rs2563336 chr5:140107199 A/G cg19875535 chr5:140030758 IK -0.36 -6.1 -0.48 1.23e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs6684514 1.000 rs12139321 chr1:156230429 A/G cg20302342 chr1:156215951 PAQR6 0.37 4.72 0.39 6.38e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs11118844 0.843 rs4601596 chr1:221914458 C/T cg04222084 chr1:221915650 DUSP10 -0.88 -5.95 -0.47 2.59e-8 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs1635 0.826 rs115041649 chr6:28274653 G/C cg15743358 chr6:28303923 ZNF323 -1.34 -5.96 -0.47 2.44e-8 Schizophrenia; TGCT cis rs7666738 0.830 rs4443293 chr4:99063120 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs61008539 0.815 rs6960062 chr7:884665 A/G cg07138768 chr7:917805 C7orf20 0.44 5.81 0.46 4.98e-8 Perceived unattractiveness to mosquitoes; TGCT cis rs11585357 0.842 rs72633804 chr1:17617024 T/C cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs1667284 1.000 rs1667284 chr18:29226208 C/T cg15259973 chr18:29078565 DSG2 -0.5 -4.78 -0.39 4.86e-6 Problematic alcohol use in trauma-exposed individuals; TGCT cis rs6598955 0.671 rs6658935 chr1:26568912 G/A cg04990556 chr1:26633338 UBXN11 0.64 5.11 0.42 1.19e-6 Obesity-related traits; TGCT cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs11690935 0.959 rs10803863 chr2:172535337 T/C cg13550731 chr2:172543902 DYNC1I2 1.2 12.8 0.75 2.01e-24 Schizophrenia; TGCT cis rs72615157 0.634 rs7789890 chr7:99800559 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.64 5.1 0.42 1.26e-6 Lung function (FEV1/FVC); TGCT cis rs9926296 0.533 rs12102290 chr16:89812617 C/T cg03388025 chr16:89894329 SPIRE2 0.48 8.07 0.59 5.2e-13 Vitiligo; TGCT cis rs769267 0.899 rs3934667 chr19:19431423 T/G cg02546618 chr19:19431379 KIAA0892;SF4 -0.62 -5.2 -0.42 8.07e-7 Tonsillectomy; TGCT cis rs548987 0.507 rs3757132 chr6:25832691 C/T cg12310025 chr6:25882481 NA -0.57 -4.67 -0.39 7.69e-6 Homocysteine levels; TGCT cis rs514406 0.893 rs499195 chr1:53344907 C/T cg24675658 chr1:53192096 ZYG11B -0.69 -8.16 -0.59 3.23e-13 Monocyte count; TGCT cis rs11669910 1 rs11669910 chr19:45741333 A/T cg20198684 chr19:45742032 NA 0.3 5.46 0.44 2.53e-7 Sum eosinophil basophil counts; TGCT cis rs7937682 0.640 rs587010 chr11:111425658 C/A cg09085632 chr11:111637200 PPP2R1B -0.8 -8.33 -0.6 1.3e-13 Primary sclerosing cholangitis; TGCT cis rs6540559 0.673 rs6694552 chr1:209976459 A/C cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs3892630 0.878 rs8112955 chr19:33191192 C/T cg22980127 chr19:33182716 NUDT19 0.7 5.18 0.42 8.9e-7 Red blood cell traits; TGCT cis rs992157 0.798 rs1017698 chr2:219170525 A/G cg00012203 chr2:219082015 ARPC2 -0.76 -7.6 -0.56 6.17e-12 Colorectal cancer; TGCT cis rs3796352 1.000 rs71301804 chr3:53073314 C/A cg07884673 chr3:53033167 SFMBT1 0.6 6.24 0.49 6.25e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg24675658 chr1:53192096 ZYG11B 0.88 11.74 0.73 7.52e-22 Monocyte count; TGCT cis rs12579753 0.917 rs12366599 chr12:82212112 C/T cg21231944 chr12:82153410 PPFIA2 -0.33 -4.45 -0.37 1.88e-5 Resting heart rate; TGCT cis rs6969780 0.915 rs4722659 chr7:27166750 C/T cg04321618 chr7:27170880 HOXA4 -0.5 -4.81 -0.4 4.35e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg01802117 chr1:53393560 SCP2 -0.44 -5.45 -0.44 2.55e-7 Monocyte count; TGCT cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg05738196 chr6:26577821 NA 0.88 10.63 0.69 3.68e-19 Intelligence (multi-trait analysis); TGCT cis rs950776 0.518 rs12594391 chr15:78816240 A/G cg06917634 chr15:78832804 PSMA4 0.96 9.71 0.66 6.43e-17 Sudden cardiac arrest; TGCT cis rs12620999 0.887 rs6723783 chr2:237963572 C/A cg23555395 chr2:238036564 NA 0.29 4.95 0.41 2.35e-6 Systemic lupus erythematosus; TGCT cis rs7267979 0.966 rs2257233 chr20:25265984 A/C cg14121845 chr20:25566513 NINL -0.5 -5.25 -0.43 6.34e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12048904 0.505 rs11166508 chr1:101233511 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.75 -6.69 -0.52 6.77e-10 Multiple sclerosis; TGCT cis rs3749237 0.557 rs7631908 chr3:49425707 T/G cg03060546 chr3:49711283 APEH 0.77 8.87 0.62 6.79e-15 Resting heart rate; TGCT cis rs7586879 0.639 rs4077678 chr2:25122840 C/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs4478858 0.654 rs113490486 chr1:31712863 C/G cg00250761 chr1:31883323 NA -0.27 -4.89 -0.4 3.11e-6 Alcohol dependence; TGCT cis rs6121246 0.697 rs6060446 chr20:30231637 T/C cg21427119 chr20:30132790 HM13 -0.37 -5.19 -0.42 8.51e-7 Mean corpuscular hemoglobin; TGCT cis rs7666738 0.830 rs7696686 chr4:98938445 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7943203 0.568 rs179110 chr11:108254999 T/C cg04873221 chr11:107992290 ACAT1 -0.59 -5.0 -0.41 1.87e-6 Red blood cell count;Mean corpuscular volume; TGCT cis rs13191362 0.938 rs35211042 chr6:162998703 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs916888 0.610 rs199438 chr17:44791643 G/A cg01341218 chr17:43662625 NA 0.81 7.07 0.54 9.95e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs61008539 0.893 rs4719460 chr7:859610 C/T cg07138768 chr7:917805 C7orf20 -0.37 -4.77 -0.39 5.12e-6 Perceived unattractiveness to mosquitoes; TGCT cis rs9972944 0.729 rs2024275 chr17:63768913 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.27 -0.43 5.91e-7 Total body bone mineral density; TGCT cis rs1129187 0.686 rs6458313 chr6:42922018 A/G cg09436375 chr6:42928200 GNMT -0.4 -5.19 -0.42 8.34e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs17433780 0.857 rs12140979 chr1:89467242 C/G cg09516651 chr1:89888402 LOC400759 0.32 5.89 0.47 3.35e-8 Carotid intima media thickness; TGCT cis rs2439831 0.681 rs1095386 chr15:43609509 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.63 0.51 9.35e-10 Lung cancer in ever smokers; TGCT cis rs3008870 0.958 rs34367328 chr1:67445321 T/C cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs933688 1.000 rs10073657 chr5:90689749 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.95 8.81 0.62 9.38e-15 Smoking behavior; TGCT cis rs7100689 0.577 rs9420349 chr10:82031160 T/C cg01528321 chr10:82214614 TSPAN14 0.7 6.87 0.52 2.78e-10 Post bronchodilator FEV1; TGCT cis rs10791097 0.694 rs10791100 chr11:130738946 T/A cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9910055 0.718 rs7212854 chr17:42254417 A/G cg10896456 chr17:42255109 ASB16;C17orf65 0.25 4.47 0.37 1.75e-5 Total body bone mineral density; TGCT cis rs3008870 0.755 rs4655662 chr1:67416432 T/C cg08660285 chr1:67390436 MIER1;WDR78 0.79 8.31 0.6 1.44e-13 Lymphocyte percentage of white cells; TGCT cis rs9910055 0.676 rs11079983 chr17:42198170 C/T cg13607699 chr17:42295918 UBTF 0.79 7.3 0.55 2.99e-11 Total body bone mineral density; TGCT cis rs2013441 1.000 rs2526480 chr17:20130074 A/G cg18979559 chr17:20280153 CCDC144C 0.48 4.84 0.4 3.75e-6 Obesity-related traits; TGCT cis rs8013055 0.846 rs8003942 chr14:105971670 A/G cg25008857 chr14:105974488 NA 0.27 4.65 0.39 8.35e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs9372498 0.536 rs62422221 chr6:118925581 T/C cg07617317 chr6:118971624 C6orf204 0.47 4.95 0.41 2.33e-6 Diastolic blood pressure; TGCT cis rs763121 0.853 rs2413544 chr22:39059404 A/C cg06022373 chr22:39101656 GTPBP1 0.77 7.51 0.56 9.9e-12 Menopause (age at onset); TGCT cis rs117533700 1.000 rs117122405 chr19:13116436 G/A cg14678774 chr19:12978360 MAST1 -0.87 -4.44 -0.37 1.94e-5 Monocyte count; TGCT trans rs1814175 0.791 rs10769625 chr11:49869887 G/A cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs9926296 0.585 rs8058009 chr16:89856439 G/A cg03388025 chr16:89894329 SPIRE2 0.49 7.48 0.56 1.2e-11 Vitiligo; TGCT cis rs75059851 0.756 rs73036081 chr11:133840156 C/T cg14047540 chr11:133829660 NA -0.57 -5.69 -0.45 8.72e-8 Schizophrenia; TGCT cis rs4455778 0.519 rs10227532 chr7:49048208 A/G cg26309511 chr7:48887640 NA 0.51 6.66 0.51 7.85e-10 Lung cancer in never smokers; TGCT cis rs1008375 1.000 rs6449323 chr4:17683916 A/T cg10189774 chr4:17578691 LAP3 0.55 4.87 0.4 3.37e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17221829 0.599 rs7112871 chr11:89404829 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 1.93e-5 Anxiety in major depressive disorder; TGCT trans rs11722228 0.549 rs62288521 chr4:10099772 G/A cg26043149 chr18:55253948 FECH 1.16 11.2 0.71 1.55e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs4319547 0.956 rs9988963 chr12:122991478 C/G cg23029597 chr12:123009494 RSRC2 -0.32 -5.13 -0.42 1.09e-6 Body mass index; TGCT cis rs7264396 0.790 rs6060562 chr20:34282053 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.87e-7 Total cholesterol levels; TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg06873352 chr17:61820015 STRADA 0.56 6.19 0.49 8.27e-9 Prudent dietary pattern; TGCT cis rs739496 0.894 rs10849947 chr12:111864684 T/C cg10833066 chr12:111807467 FAM109A 0.36 5.51 0.44 2.01e-7 Platelet count; TGCT cis rs78545713 0.892 rs11751286 chr6:26241361 C/G cg12260798 chr6:26240519 HIST1H4F -0.51 -4.68 -0.39 7.29e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs7677751 0.537 rs964259 chr4:55057222 C/G cg17187183 chr4:55093834 PDGFRA 0.42 5.28 0.43 5.49e-7 Corneal astigmatism; TGCT cis rs782590 0.620 rs7596377 chr2:55888612 T/A cg18811423 chr2:55921094 PNPT1 -0.61 -5.57 -0.45 1.5e-7 Metabolic syndrome; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg01411255 chr17:61851458 DDX42;CCDC47 -0.77 -7.48 -0.56 1.17e-11 Prudent dietary pattern; TGCT cis rs77633900 0.614 rs203753 chr15:76946195 A/T cg21673338 chr15:77095150 SCAPER -0.52 -4.92 -0.4 2.72e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs10479542 0.766 rs6894980 chr5:178974592 C/T cg21226059 chr5:178986404 RUFY1 0.46 5.03 0.41 1.66e-6 Lung cancer; TGCT cis rs9467711 0.659 rs34246779 chr6:26549212 G/A cg16898833 chr6:26189333 HIST1H4D 1.25 5.86 0.47 3.88e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs3820068 0.580 rs12760698 chr1:16009814 G/A cg17385448 chr1:15911702 AGMAT 0.34 4.69 0.39 7.06e-6 Systolic blood pressure; TGCT cis rs11651000 0.625 rs11079786 chr17:45805916 A/G cg24803719 chr17:45855879 NA 0.45 5.04 0.41 1.6e-6 IgG glycosylation; TGCT cis rs13108904 0.967 rs4974582 chr4:1279687 C/T cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs4796354 0.639 rs4796558 chr17:6696984 A/C cg04115740 chr17:6690948 FBXO39 0.25 4.45 0.37 1.86e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs2451732 chr6:26622904 A/T cg02458000 chr6:26745757 NA -0.56 -5.06 -0.41 1.45e-6 Intelligence (multi-trait analysis); TGCT cis rs6831352 0.703 rs2602854 chr4:100028651 C/T cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs909674 0.690 rs5750823 chr22:39829973 C/T cg11247378 chr22:39784982 NA -0.73 -8.55 -0.61 3.78e-14 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs7666738 0.830 rs34870112 chr4:99045815 T/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs589448 0.967 rs634512 chr12:69754012 C/T cg14784868 chr12:69753453 YEATS4 0.9 10.55 0.69 5.67e-19 Cerebrospinal fluid biomarker levels; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg21548813 chr6:291882 DUSP22 -0.73 -7.58 -0.56 6.89e-12 Menopause (age at onset); TGCT cis rs478304 0.593 rs6591188 chr11:65467953 T/C cg27068330 chr11:65405492 SIPA1 -1.01 -11.31 -0.71 8.13e-21 Acne (severe); TGCT cis rs9611565 0.879 rs5758307 chr22:41750219 A/G cg06634786 chr22:41940651 POLR3H -0.8 -7.58 -0.56 7.14e-12 Vitiligo; TGCT cis rs2070488 0.775 rs11926767 chr3:38527913 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.69 -6.13 -0.48 1.09e-8 Electrocardiographic conduction measures; TGCT cis rs7394579 1 rs7394579 chr11:61581450 A/G cg01500311 chr11:61656094 FADS3 -0.28 -4.47 -0.37 1.75e-5 Red cell distribution width;Mean platelet volume; TGCT cis rs7635838 0.654 rs346083 chr3:11280017 T/C cg00170343 chr3:11313890 ATG7 0.66 6.26 0.49 5.67e-9 HDL cholesterol; TGCT cis rs9399135 0.967 rs6569990 chr6:135365818 C/T cg24558204 chr6:135376177 HBS1L 0.46 4.55 0.38 1.24e-5 Red blood cell count; TGCT cis rs9308731 0.965 rs6758181 chr2:111886914 C/T cg04202892 chr2:111875749 ACOXL 0.44 4.63 0.38 9.09e-6 Chronic lymphocytic leukemia; TGCT cis rs28595532 1.000 rs114682099 chr4:119702004 C/T cg21605333 chr4:119757512 SEC24D 1.41 7.28 0.55 3.45e-11 Cannabis dependence symptom count; TGCT cis rs10791097 0.690 rs12286234 chr11:130730528 T/C cg12179176 chr11:130786555 SNX19 0.73 8.6 0.61 2.98e-14 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9527 0.590 rs1807298 chr10:104870218 G/A cg15744005 chr10:104629667 AS3MT -0.43 -4.9 -0.4 2.89e-6 Arsenic metabolism; TGCT cis rs9916302 0.595 rs4795371 chr17:37636695 T/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.85 -0.4 3.6e-6 Glomerular filtration rate (creatinine); TGCT cis rs7772486 0.846 rs1854901 chr6:146325685 T/C cg23711669 chr6:146136114 FBXO30 0.84 9.12 0.63 1.72e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs13217239 0.646 rs11756275 chr6:27007113 A/C cg26531700 chr6:26746687 NA -0.68 -6.71 -0.52 6.07e-10 Schizophrenia; TGCT cis rs7943191 0.805 rs12226821 chr11:62369018 C/G cg22862634 chr11:62369728 EML3;MTA2 0.6 5.98 0.47 2.24e-8 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs3008870 0.920 rs3008865 chr1:67402838 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 11.97 0.73 2.07e-22 Lymphocyte percentage of white cells; TGCT trans rs1814175 0.817 rs1851858 chr11:49855638 G/A cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs950169 0.887 rs62029593 chr15:84955180 A/G cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs2153535 0.601 rs4960414 chr6:8438541 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs514406 0.621 rs928452 chr1:53195926 G/C cg22166914 chr1:53195759 ZYG11B -0.5 -9.42 -0.65 3.19e-16 Monocyte count; TGCT cis rs9611565 0.559 rs12483860 chr22:41961916 C/T cg03806693 chr22:41940476 POLR3H -1.08 -11.36 -0.71 6.34e-21 Vitiligo; TGCT cis rs9916302 0.904 rs634365 chr17:37436966 C/T cg15445000 chr17:37608096 MED1 0.31 4.68 0.39 7.45e-6 Glomerular filtration rate (creatinine); TGCT cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg24531977 chr5:56204891 C5orf35 -0.75 -7.31 -0.55 2.87e-11 Initial pursuit acceleration; TGCT cis rs13086611 1 rs13086611 chr3:49385417 A/T cg03060546 chr3:49711283 APEH -0.65 -5.65 -0.45 1.04e-7 Educational attainment; TGCT cis rs1371867 0.810 rs2919470 chr8:101233301 C/A cg00191853 chr8:101177733 SPAG1 0.25 4.96 0.41 2.24e-6 Atrioventricular conduction; TGCT cis rs11648796 0.680 rs11248946 chr16:768597 A/G cg27144592 chr16:783916 NARFL 0.4 5.48 0.44 2.3e-7 Height; TGCT cis rs6089584 0.850 rs6142938 chr20:60627723 A/C cg13770153 chr20:60521292 NA -0.63 -7.95 -0.58 9.71e-13 Body mass index; TGCT cis rs59698941 0.550 rs11748063 chr5:132200943 C/T cg21474247 chr5:131268130 NA 0.31 4.77 0.39 5.01e-6 Apolipoprotein A-IV levels; TGCT cis rs1862618 0.853 rs10051747 chr5:56083289 C/A cg24531977 chr5:56204891 C5orf35 -0.74 -7.14 -0.54 7.06e-11 Initial pursuit acceleration; TGCT cis rs916888 0.610 rs199446 chr17:44813169 G/A cg15921436 chr17:44337874 NA -0.41 -6.27 -0.49 5.47e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7659604 0.539 rs7686200 chr4:122764553 C/T cg19748678 chr4:122722346 EXOSC9 0.89 8.94 0.63 4.53e-15 Type 2 diabetes; TGCT cis rs2243480 1.000 rs316322 chr7:65611233 G/C cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs5750830 0.649 rs5757664 chr22:39821536 A/G cg24399712 chr22:39784796 NA -1.06 -12.58 -0.75 6.72e-24 Intelligence (multi-trait analysis); TGCT cis rs9916302 0.904 rs2061342 chr17:37405657 T/G cg07936489 chr17:37558343 FBXL20 -0.65 -5.24 -0.43 6.62e-7 Glomerular filtration rate (creatinine); TGCT cis rs9921338 0.961 rs57579443 chr16:11442997 G/C cg00044050 chr16:11439710 C16orf75 -0.91 -7.1 -0.54 8.47e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4822044 0.560 rs7284839 chr22:42010902 C/T cg13695892 chr22:41940480 POLR3H 0.88 8.46 0.6 6.38e-14 Cannabis dependence symptom count; TGCT cis rs7618915 0.547 rs11719685 chr3:52676065 C/T cg07507251 chr3:52567010 NT5DC2 0.48 6.73 0.52 5.48e-10 Bipolar disorder; TGCT cis rs4700695 0.668 rs166180 chr5:65499225 C/T cg21114390 chr5:65439923 SFRS12 -0.81 -7.72 -0.57 3.34e-12 Facial morphology (factor 19); TGCT cis rs4321325 0.668 rs56346774 chr2:127932551 G/A cg09760422 chr2:128146352 NA 0.44 4.47 0.37 1.76e-5 Protein C levels; TGCT cis rs6866344 0.697 rs11739893 chr5:178127837 G/A cg03877680 chr5:178157825 ZNF354A 0.72 5.61 0.45 1.27e-7 Neutrophil percentage of white cells; TGCT cis rs259282 0.574 rs4805780 chr19:33114406 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.5 4.56 0.38 1.2e-5 Schizophrenia; TGCT cis rs514406 0.679 rs11585495 chr1:53244331 T/C cg01802117 chr1:53393560 SCP2 0.49 6.02 0.48 1.86e-8 Monocyte count; TGCT cis rs36051895 0.695 rs11794778 chr9:5023794 G/T cg02405213 chr9:5042618 JAK2 -0.77 -10.45 -0.68 1e-18 Pediatric autoimmune diseases; TGCT cis rs42648 0.935 rs42624 chr7:89957541 C/G cg25739043 chr7:89950458 NA -0.75 -7.61 -0.56 5.9e-12 Homocysteine levels; TGCT cis rs2439831 0.681 rs825739 chr15:43592428 T/G cg27015174 chr15:43622946 ADAL;LCMT2 0.88 6.39 0.5 3.1e-9 Lung cancer in ever smokers; TGCT cis rs6674176 0.628 rs4660759 chr1:44432500 C/G cg13606994 chr1:44402422 ARTN -0.47 -5.08 -0.41 1.37e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6840360 0.550 rs7683134 chr4:152503362 A/C cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs2197308 0.619 rs4002730 chr12:37876400 T/C cg13010199 chr12:38710504 ALG10B 0.67 5.38 0.44 3.57e-7 Morning vs. evening chronotype; TGCT cis rs10492096 0.947 rs10849482 chr12:6635274 G/A cg00459232 chr12:6309025 CD9 0.36 4.47 0.37 1.77e-5 Hip geometry; TGCT cis rs1348850 0.914 rs4893823 chr2:178285811 C/T cg22681709 chr2:178499509 PDE11A 0.35 4.56 0.38 1.2e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9457247 0.967 rs385460 chr6:167403888 A/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT trans rs7726839 0.561 rs72703046 chr5:580129 T/C cg25482853 chr8:67687455 SGK3 1.05 9.29 0.64 6.67e-16 Obesity-related traits; TGCT cis rs711830 0.965 rs6755777 chr2:177043226 T/G cg13092806 chr2:177043255 NA 0.77 6.12 0.48 1.14e-8 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs651907 0.557 rs7629753 chr3:101371922 C/T cg12386194 chr3:101231763 SENP7 -0.48 -4.72 -0.39 6.28e-6 Colorectal cancer; TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg25767906 chr1:53392781 SCP2 -0.61 -7.2 -0.54 5.02e-11 Monocyte count; TGCT cis rs526231 0.543 rs7709726 chr5:102327463 A/G cg23492399 chr5:102201601 PAM 0.51 4.47 0.37 1.78e-5 Primary biliary cholangitis; TGCT cis rs74417235 0.517 rs13179034 chr5:154059487 C/A cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs10504229 1.000 rs61998259 chr8:58192290 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs1941023 0.503 rs894591 chr11:60132647 T/C cg08716584 chr11:60157161 MS4A7 -0.31 -4.53 -0.38 1.34e-5 Congenital heart disease (maternal effect); TGCT cis rs832540 0.629 rs3309 chr5:56092779 A/T cg24531977 chr5:56204891 C5orf35 0.52 4.99 0.41 1.97e-6 Coronary artery disease; TGCT cis rs2197308 0.631 rs4882308 chr12:38446252 G/C cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Morning vs. evening chronotype; TGCT cis rs1371867 0.875 rs1788176 chr8:101332112 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs3733585 0.699 rs6449174 chr4:9966422 C/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.5 -0.56 1.05e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs769267 0.965 rs4808938 chr19:19401218 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs682748 0.846 rs6859179 chr5:17141484 C/G cg23987134 chr5:17158319 LOC285696 -0.21 -5.19 -0.42 8.4e-7 Hippocampal atrophy; TGCT cis rs10114408 0.959 rs10821246 chr9:96645759 A/T cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs881375 0.678 rs10118357 chr9:123680068 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.51 5.77 0.46 5.87e-8 Rheumatoid arthritis; TGCT cis rs7829975 0.811 rs7011229 chr8:8543324 T/C cg15556689 chr8:8085844 FLJ10661 -0.69 -6.07 -0.48 1.46e-8 Mood instability; TGCT cis rs910316 1.000 rs3742773 chr14:75579643 A/G cg23033748 chr14:75592666 NEK9 0.28 4.72 0.39 6.22e-6 Height; TGCT cis rs12908161 0.960 rs11633450 chr15:85307287 C/T cg11189052 chr15:85197271 WDR73 0.71 5.21 0.42 7.63e-7 Schizophrenia; TGCT cis rs116161686 0.521 rs701941 chr1:210439529 G/A cg22029157 chr1:209979665 IRF6 0.62 4.46 0.37 1.79e-5 Coronary artery disease; TGCT cis rs7811142 0.830 rs73401443 chr7:99977582 T/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 7.0 0.53 1.44e-10 Platelet count; TGCT cis rs10423674 0.526 rs11668545 chr19:18829529 C/T cg20185461 chr19:18899082 COMP -0.5 -4.73 -0.39 6.09e-6 Menarche (age at onset); TGCT cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg21724239 chr8:58056113 NA 0.42 5.04 0.41 1.59e-6 Developmental language disorder (linguistic errors); TGCT cis rs6951245 0.832 rs79808627 chr7:1092519 C/G cg27454412 chr7:1067447 C7orf50 0.52 4.57 0.38 1.16e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1401999 1.000 rs2313217 chr3:183635997 A/G cg01324343 chr3:183735012 ABCC5 0.85 11.48 0.72 3.16e-21 Anterior chamber depth; TGCT cis rs3820928 0.874 rs3752895 chr2:227886773 A/G cg11843606 chr2:227700838 RHBDD1 -0.51 -4.71 -0.39 6.63e-6 Pulmonary function; TGCT cis rs2718812 0.792 rs3772680 chr3:133371807 A/G cg08048268 chr3:133502702 NA -0.38 -4.73 -0.39 6.03e-6 Iron status biomarkers; TGCT cis rs9303401 0.659 rs62083410 chr17:56964386 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs7760949 0.963 rs4142889 chr6:13918461 T/A cg27413430 chr6:13925136 RNF182 0.61 5.8 0.46 5.08e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs769267 0.930 rs4808959 chr19:19572108 T/G cg08509172 chr19:19383838 TM6SF2 -0.35 -4.59 -0.38 1.08e-5 Tonsillectomy; TGCT cis rs9435341 0.965 rs1762485 chr1:107625056 C/T cg09367891 chr1:107599246 PRMT6 -0.61 -5.2 -0.42 8.08e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs12048904 0.541 rs6699536 chr1:101276544 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.87 7.77 0.57 2.6e-12 Multiple sclerosis; TGCT cis rs854765 0.547 rs7224047 chr17:17932931 G/A cg04398451 chr17:18023971 MYO15A -0.32 -5.15 -0.42 1.01e-6 Total body bone mineral density; TGCT cis rs4851254 0.660 rs56037757 chr2:100690130 A/G cg07810366 chr2:100720526 AFF3 -0.49 -5.22 -0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs11252926 0.550 rs10904148 chr10:454551 G/T cg18196295 chr10:418757 DIP2C 0.28 4.45 0.37 1.92e-5 Psychosis in Alzheimer's disease; TGCT cis rs35306767 0.855 rs35666723 chr10:867346 A/G cg26597838 chr10:835615 NA 0.8 12.0 0.73 1.67e-22 Eosinophil percentage of granulocytes; TGCT cis rs7940866 0.903 rs7942900 chr11:130839244 G/A cg12179176 chr11:130786555 SNX19 0.53 5.05 0.41 1.56e-6 Schizophrenia; TGCT cis rs17376456 0.569 rs6556839 chr5:93206292 T/C cg21475434 chr5:93447410 FAM172A -0.7 -5.15 -0.42 1.02e-6 Diabetic retinopathy; TGCT cis rs1552244 0.816 rs56271597 chr3:10042790 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.43 -0.5 2.53e-9 Alzheimer's disease; TGCT cis rs1371867 0.875 rs1660344 chr8:101324659 A/G cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs2439831 0.867 rs12443102 chr15:43932103 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.86 6.37 0.5 3.3e-9 Lung cancer in ever smokers; TGCT cis rs1153858 1.000 rs12441971 chr15:45671957 A/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg23205692 chr1:25664452 TMEM50A 0.47 4.97 0.41 2.22e-6 Erythrocyte sedimentation rate; TGCT cis rs66573146 1.000 rs59683609 chr4:6964910 C/G cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs35883536 0.566 rs10783141 chr1:101043897 G/A cg10298815 chr1:101004474 GPR88 -0.25 -4.7 -0.39 6.67e-6 Monocyte count; TGCT cis rs3091242 0.836 rs34997029 chr1:25783823 A/G cg23205692 chr1:25664452 TMEM50A -0.47 -4.95 -0.41 2.32e-6 Erythrocyte sedimentation rate; TGCT cis rs6032067 0.673 rs36019441 chr20:43892401 G/A cg16667508 chr20:43936853 MATN4;RBPJL -0.45 -6.37 -0.5 3.36e-9 Blood protein levels; TGCT cis rs317689 0.513 rs317678 chr12:69692166 C/G cg11871910 chr12:69753446 YEATS4 0.63 6.11 0.48 1.18e-8 Response to diuretic therapy; TGCT cis rs769267 0.929 rs2905424 chr19:19473445 T/C cg03709012 chr19:19516395 GATAD2A -0.78 -6.42 -0.5 2.58e-9 Tonsillectomy; TGCT cis rs2295359 1.000 rs11209006 chr1:67619259 T/G cg12940439 chr1:67600707 NA 0.56 6.04 0.48 1.63e-8 Psoriasis; TGCT cis rs36051895 0.659 rs59225790 chr9:5042757 G/A cg02405213 chr9:5042618 JAK2 -0.72 -9.64 -0.65 9.46e-17 Pediatric autoimmune diseases; TGCT cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs950169 0.545 rs4842841 chr15:84641125 G/A cg11189052 chr15:85197271 WDR73 0.58 4.65 0.39 8.49e-6 Schizophrenia; TGCT cis rs2070488 0.804 rs35463537 chr3:38498248 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.79 7.9 0.58 1.3e-12 Electrocardiographic conduction measures; TGCT cis rs9393777 0.513 rs6936555 chr6:26640886 C/T cg15659132 chr6:26577336 NA -0.77 -5.48 -0.44 2.26e-7 Intelligence (multi-trait analysis); TGCT cis rs7809950 0.862 rs2299421 chr7:106946195 C/G cg23024343 chr7:107201750 COG5 -0.3 -4.74 -0.39 5.82e-6 Coronary artery disease; TGCT cis rs7811142 0.562 rs7786844 chr7:99934008 T/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.89 7.32 0.55 2.74e-11 Platelet count; TGCT cis rs2197308 0.626 rs6581156 chr12:37858731 C/A cg26384229 chr12:38710491 ALG10B -0.67 -6.02 -0.48 1.82e-8 Morning vs. evening chronotype; TGCT cis rs17376456 0.825 rs17372649 chr5:93126096 C/G cg21475434 chr5:93447410 FAM172A 0.63 4.77 0.39 5.03e-6 Diabetic retinopathy; TGCT cis rs2153535 0.601 rs6906170 chr6:8543128 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.63 0.45 1.14e-7 Motion sickness; TGCT cis rs1218582 0.772 rs4845693 chr1:154911257 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.63 6.72 0.52 5.88e-10 Prostate cancer; TGCT cis rs6570726 0.791 rs6570694 chr6:145911204 C/G cg05347473 chr6:146136440 FBXO30 0.51 4.75 0.39 5.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4727027 0.680 rs6464941 chr7:148826352 A/G cg23583168 chr7:148888333 NA -0.66 -7.38 -0.55 2e-11 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs17741873 0.779 rs12573092 chr10:75600016 A/G cg07699608 chr10:75541558 CHCHD1 0.7 4.88 0.4 3.23e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs1729951 0.575 rs1654926 chr3:136709924 G/A cg21827317 chr3:136751795 NA 0.41 5.79 0.46 5.43e-8 Neuroticism; TGCT cis rs4918072 0.917 rs12571879 chr10:105663346 G/A cg11005552 chr10:105648138 OBFC1 0.41 5.4 0.44 3.29e-7 Coronary artery disease; TGCT cis rs6671200 1.000 rs76064624 chr1:95661033 A/G cg03123541 chr1:95699097 RWDD3 0.87 6.17 0.48 8.81e-9 Stearic acid (18:0) levels; TGCT cis rs2204008 0.811 rs8189445 chr12:38276295 T/C cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.19e-11 Bladder cancer; TGCT cis rs67311347 0.713 rs114569261 chr3:40314580 G/A cg13683864 chr3:40499215 RPL14 -0.89 -8.71 -0.62 1.65e-14 Renal cell carcinoma; TGCT cis rs6500602 0.563 rs917305 chr16:4440593 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.41 5.1 0.42 1.23e-6 Schizophrenia; TGCT cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg20607798 chr8:58055168 NA 0.6 4.95 0.41 2.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs6846229 chr4:99016546 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1797081 0.646 rs7090256 chr10:16851949 T/G cg23933602 chr10:16859644 RSU1 0.82 8.57 0.61 3.41e-14 Platelet distribution width; TGCT cis rs9393777 0.513 rs9393739 chr6:26646966 T/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs1153858 1.000 rs4271549 chr15:45652730 G/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs12477438 0.605 rs4585080 chr2:99557327 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.83 -8.22 -0.59 2.29e-13 Chronic sinus infection; TGCT cis rs12477438 0.572 rs10170063 chr2:99655639 A/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs7236492 0.748 rs11663658 chr18:77197555 T/C cg15644404 chr18:77186268 NFATC1 -0.35 -4.76 -0.39 5.22e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs514406 0.825 rs6693210 chr1:53223398 A/G cg08736216 chr1:53307985 ZYG11A 0.26 4.95 0.41 2.32e-6 Monocyte count; TGCT cis rs6484504 0.532 rs7116443 chr11:31283170 T/C cg26647111 chr11:31128758 NA -0.35 -4.85 -0.4 3.69e-6 Red blood cell count; TGCT cis rs7772486 0.790 rs1133832 chr6:146205604 C/T cg23711669 chr6:146136114 FBXO30 -0.86 -9.77 -0.66 4.48e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs3960554 0.808 rs78587454 chr7:75688672 G/A cg17325771 chr7:75508891 RHBDD2 -0.54 -4.63 -0.38 8.97e-6 Eotaxin levels; TGCT cis rs11031096 0.542 rs11828337 chr11:3976974 T/G cg18678763 chr11:4115507 RRM1 -0.41 -5.09 -0.42 1.27e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7635838 0.650 rs1375206 chr3:11339117 C/G cg00170343 chr3:11313890 ATG7 0.62 6.09 0.48 1.28e-8 HDL cholesterol; TGCT cis rs2762353 0.718 rs1165205 chr6:25870542 A/T cg12310025 chr6:25882481 NA 0.69 7.5 0.56 1.07e-11 Blood metabolite levels; TGCT cis rs858239 0.601 rs6948469 chr7:23174766 G/T cg05602783 chr7:23145260 KLHL7 -0.63 -5.28 -0.43 5.64e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9818758 0.607 rs34566463 chr3:49245077 T/C cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs5167 0.781 rs11672748 chr19:45490192 A/G cg09555818 chr19:45449301 APOC2 0.23 5.02 0.41 1.78e-6 Blood protein levels; TGCT cis rs8177253 0.965 rs4854760 chr3:133498741 C/T cg20276088 chr3:133502917 NA 0.25 5.27 0.43 5.97e-7 Iron status biomarkers; TGCT cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.53 0.44 1.81e-7 Height; TGCT cis rs1577917 0.917 rs4707226 chr6:86527828 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs10504229 0.593 rs74760806 chr8:58024785 C/T cg08280861 chr8:58055591 NA 0.36 5.16 0.42 9.31e-7 Developmental language disorder (linguistic errors); TGCT cis rs6912958 0.781 rs13193380 chr6:88297057 G/T cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs739496 0.579 rs4766705 chr12:112333660 C/A cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs6582630 0.502 rs8186661 chr12:38380781 G/A cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.76e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9926296 0.607 rs2079672 chr16:89884917 A/G cg26513180 chr16:89883248 FANCA -0.75 -7.52 -0.56 9.5e-12 Vitiligo; TGCT cis rs4566357 1.000 rs2251223 chr2:227914975 T/G cg11843606 chr2:227700838 RHBDD1 -0.58 -5.34 -0.43 4.26e-7 Coronary artery disease; TGCT cis rs7172809 0.573 rs17468413 chr15:77544510 T/A cg22256960 chr15:77711686 NA -0.48 -4.6 -0.38 1.02e-5 Glucose homeostasis traits; TGCT cis rs9486719 0.947 rs2472893 chr6:96870048 G/C cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs2594989 0.943 rs346073 chr3:11298181 G/A cg00170343 chr3:11313890 ATG7 0.64 4.65 0.39 8.23e-6 Circulating chemerin levels; TGCT cis rs10779751 0.922 rs2295079 chr1:11322565 C/G cg08854313 chr1:11322531 MTOR 0.93 10.56 0.69 5.37e-19 Body mass index; TGCT cis rs10876993 0.680 rs2277322 chr12:58009202 T/C cg15848620 chr12:58087721 OS9 0.68 4.97 0.41 2.21e-6 Celiac disease or Rheumatoid arthritis; TGCT cis rs986417 1.000 rs1116854 chr14:60917496 C/A cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs7666738 0.753 rs1527520 chr4:98929164 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12908161 0.683 rs12903256 chr15:85308141 G/T cg17173187 chr15:85201210 NMB 0.39 4.6 0.38 1.01e-5 Schizophrenia; TGCT cis rs9300255 0.596 rs7304782 chr12:123719444 A/G cg00376283 chr12:123451042 ABCB9 -0.7 -5.9 -0.47 3.3e-8 Neutrophil percentage of white cells; TGCT cis rs896854 0.552 rs2515236 chr8:95934907 A/G cg16049864 chr8:95962084 TP53INP1 0.61 7.04 0.53 1.18e-10 Type 2 diabetes; TGCT cis rs6088590 1.000 rs6087623 chr20:33317662 C/G cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT cis rs10089 1.000 rs10060390 chr5:127452947 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs2153535 0.601 rs4960414 chr6:8438541 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs4820539 0.708 rs5751591 chr22:23489042 G/A cg21100191 chr22:23484243 RTDR1 0.8 8.8 0.62 1e-14 Bone mineral density; TGCT cis rs2562456 0.583 rs4809144 chr19:21772730 C/T cg13978929 chr19:21580086 ZNF493 -0.56 -4.72 -0.39 6.29e-6 Pain; TGCT cis rs933688 1.000 rs2839728 chr5:90727412 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 10.12 0.67 6.32e-18 Smoking behavior; TGCT cis rs1153858 1.000 rs1346266 chr15:45694516 G/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs5769707 0.967 rs739241 chr22:50052921 G/A cg05373962 chr22:49881684 NA -0.32 -6.66 -0.51 7.86e-10 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1568889 1.000 rs2354427 chr11:28049623 T/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs1008375 1.000 rs10939747 chr4:17691166 C/A cg18681998 chr4:17616180 MED28 0.79 7.53 0.56 9.23e-12 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11098499 0.599 rs3864142 chr4:120266191 A/T cg09307838 chr4:120376055 NA 0.56 5.49 0.44 2.18e-7 Corneal astigmatism; TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.45 0.56 1.42e-11 Prudent dietary pattern; TGCT cis rs514406 0.823 rs501006 chr1:53368292 T/A cg16325326 chr1:53192061 ZYG11B 0.6 6.97 0.53 1.68e-10 Monocyte count; TGCT cis rs4808199 0.947 rs7250658 chr19:19571100 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.15 0.42 9.94e-7 Nonalcoholic fatty liver disease; TGCT cis rs3820928 0.904 rs2894623 chr2:227766112 T/C cg11843606 chr2:227700838 RHBDD1 -0.51 -4.49 -0.37 1.59e-5 Pulmonary function; TGCT cis rs7828089 0.519 rs2443500 chr8:22352342 C/T cg12081754 chr8:22256438 SLC39A14 0.29 4.5 0.37 1.55e-5 Verbal declarative memory; TGCT cis rs9486719 0.895 rs12190520 chr6:96928620 A/C cg18709589 chr6:96969512 KIAA0776 -0.72 -5.24 -0.43 6.58e-7 Migraine;Coronary artery disease; TGCT trans rs77457752 0.690 rs12335400 chr9:13912195 A/G cg18948646 chr4:83674694 SCD5;MIR575 0.55 6.62 0.51 9.75e-10 Breast cancer; TGCT cis rs981844 0.603 rs13132437 chr4:154748006 T/G cg14289246 chr4:154710475 SFRP2 -0.99 -9.05 -0.63 2.54e-15 Response to statins (LDL cholesterol change); TGCT cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg12310025 chr6:25882481 NA 0.79 8.09 0.59 4.59e-13 Blood metabolite levels; TGCT cis rs11785400 1.000 rs4266629 chr8:143736635 A/G cg24634471 chr8:143751801 JRK 0.56 6.12 0.48 1.16e-8 Schizophrenia; TGCT cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg03188948 chr7:1209495 NA 0.64 5.38 0.43 3.61e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9297145 0.761 rs12534399 chr7:98746401 A/G cg05967295 chr7:98741636 SMURF1 1.01 12.87 0.76 1.33e-24 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs10791097 0.694 rs61910787 chr11:130744473 G/A cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9486715 0.867 rs4438964 chr6:96917563 T/G cg06623918 chr6:96969491 KIAA0776 1.1 15.31 0.81 2.34e-30 Headache; TGCT trans rs1814175 0.935 rs11040465 chr11:49689323 C/T cg15704280 chr7:45808275 SEPT13 -0.61 -6.69 -0.51 6.8e-10 Height; TGCT cis rs2932538 0.961 rs6690292 chr1:113188419 C/T cg22162597 chr1:113214053 CAPZA1 -0.26 -5.82 -0.46 4.83e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs12681287 0.640 rs7841690 chr8:87365359 T/C cg27223183 chr8:87520930 FAM82B 0.9 6.71 0.52 6.12e-10 Caudate activity during reward; TGCT cis rs9646954 0.542 rs11674830 chr2:101024735 A/G cg08017756 chr2:100939284 LONRF2 -0.29 -4.57 -0.38 1.15e-5 Intelligence (multi-trait analysis); TGCT cis rs17384381 0.834 rs12130380 chr1:85901309 T/C cg16011679 chr1:85725395 C1orf52 0.82 6.71 0.52 6.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6684514 1.000 rs12040868 chr1:156284803 G/T cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6964587 0.732 rs12539523 chr7:91710836 G/A cg22709100 chr7:91322751 NA 0.27 4.46 0.37 1.84e-5 Breast cancer; TGCT cis rs7172809 0.524 rs74025105 chr15:77572357 G/A cg22256960 chr15:77711686 NA -0.48 -4.67 -0.39 7.76e-6 Glucose homeostasis traits; TGCT cis rs4689388 0.750 rs12642481 chr4:6301058 G/A cg14416269 chr4:6271139 WFS1 0.48 5.91 0.47 3.02e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9653442 0.564 rs13013594 chr2:100784190 A/G cg07810366 chr2:100720526 AFF3 -0.36 -5.26 -0.43 6.14e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs6840360 1.000 rs749982 chr4:152601353 A/G cg17479576 chr4:152424074 FAM160A1 -0.52 -5.66 -0.45 9.86e-8 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.590 rs36064164 chr2:26502768 C/T cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs7937682 0.883 rs512669 chr11:111467893 G/A cg09085632 chr11:111637200 PPP2R1B -0.98 -9.83 -0.66 3.23e-17 Primary sclerosing cholangitis; TGCT cis rs6669919 0.967 rs11119752 chr1:211675765 A/G cg26515805 chr1:211431828 RCOR3 -0.38 -4.49 -0.37 1.6e-5 Intelligence (multi-trait analysis); TGCT cis rs7000551 0.725 rs2449349 chr8:22383284 A/G cg12081754 chr8:22256438 SLC39A14 0.28 4.51 0.38 1.46e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4711350 0.862 rs602399 chr6:33713779 C/T cg18005901 chr6:33739558 LEMD2 0.57 5.9 0.47 3.23e-8 Schizophrenia; TGCT cis rs10883723 0.738 rs3781290 chr10:104244948 G/C cg05855489 chr10:104503620 C10orf26 -0.58 -5.07 -0.41 1.42e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs854765 0.547 rs9894138 chr17:17964345 G/A cg09796270 chr17:17721594 SREBF1 -0.27 -5.23 -0.42 7.04e-7 Total body bone mineral density; TGCT cis rs709400 0.663 rs3783402 chr14:103967929 C/G cg12935359 chr14:103987150 CKB -0.36 -5.64 -0.45 1.11e-7 Body mass index; TGCT cis rs17122693 0.539 rs72681610 chr14:51117773 T/C cg04730355 chr14:51134070 SAV1 1.04 6.32 0.49 4.38e-9 Cognitive performance; TGCT cis rs6951245 1.000 rs884977 chr7:1066410 T/C cg26224354 chr7:1096374 C7orf50;GPR146 -0.3 -4.7 -0.39 6.73e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2997447 0.846 rs61775425 chr1:26405634 A/T cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.17e-5 QRS complex (12-leadsum); TGCT cis rs875971 0.737 rs7803424 chr7:65880605 T/C cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.61 -5.09 -0.42 1.3e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg03517284 chr6:25882590 NA -0.81 -8.33 -0.6 1.24e-13 Blood metabolite levels; TGCT cis rs12510870 0.599 rs2008288 chr4:74447800 A/G cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs1799949 0.965 rs8070179 chr17:41202688 G/A cg10047753 chr17:41438598 NA 0.68 6.16 0.48 9.22e-9 Menopause (age at onset); TGCT cis rs10089 1.000 rs1864922 chr5:127420700 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.8 7.64 0.57 5.24e-12 Ileal carcinoids; TGCT cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.25e-17 Bipolar disorder; TGCT trans rs7618501 0.933 rs6809431 chr3:49804119 A/G cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs8017423 0.647 rs12587362 chr14:90821227 G/T cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs11969893 0.850 rs9791284 chr6:101353886 G/A cg12253828 chr6:101329408 ASCC3 1.45 5.99 0.47 2.15e-8 Economic and political preferences (immigration/crime); TGCT cis rs138249 1.000 rs138244 chr22:50565367 C/T cg24864161 chr22:50528282 MOV10L1 0.46 4.75 0.39 5.48e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs899997 1.000 rs12899940 chr15:79001699 A/G cg04896959 chr15:78267971 NA -0.33 -4.94 -0.41 2.44e-6 Coronary artery disease or large artery stroke; TGCT cis rs9467773 1.000 rs2208331 chr6:26507319 A/G cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT cis rs9993613 0.875 rs1842660 chr4:73479875 A/C cg15102770 chr4:73434591 ADAMTS3 0.52 4.89 0.4 3.07e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs10504229 1.000 rs72650900 chr8:58185675 T/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2880765 0.835 rs7178991 chr15:86050944 G/C cg13263323 chr15:86062960 AKAP13 -0.22 -4.88 -0.4 3.14e-6 Coronary artery disease; TGCT cis rs9902453 0.704 rs2617874 chr17:28085172 C/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.42 0.55 1.64e-11 Coffee consumption (cups per day); TGCT cis rs2836950 0.509 rs11088466 chr21:40580017 T/A cg06238570 chr21:40685208 BRWD1 -0.62 -6.35 -0.5 3.74e-9 Menarche (age at onset); TGCT cis rs56104184 0.775 rs117744769 chr19:49402686 G/T cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs929596 0.785 rs34352510 chr2:234650562 T/C cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.34 -5.41 -0.44 3.11e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs3770081 1.000 rs6724025 chr2:86200835 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -1.24 -4.98 -0.41 2.07e-6 Facial emotion recognition (sad faces); TGCT cis rs1005224 1.000 rs1158282 chr14:76172916 C/G cg04684003 chr14:76127793 TTLL5;C14orf1 -0.59 -5.23 -0.42 7.08e-7 Large artery stroke; TGCT cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.44 -0.6 6.87e-14 Platelet count; TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 6.93e-9 Prudent dietary pattern; TGCT cis rs17122693 0.748 rs1009292 chr14:51143683 A/T cg04730355 chr14:51134070 SAV1 1.33 12.04 0.73 1.37e-22 Cognitive performance; TGCT cis rs4727027 0.522 rs6956736 chr7:148893472 G/C cg23583168 chr7:148888333 NA -0.74 -7.8 -0.57 2.15e-12 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs873946 0.504 rs4880275 chr10:134576552 C/T cg27286337 chr10:134555280 INPP5A 0.41 5.24 0.43 6.65e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs56104184 0.775 rs3760785 chr19:49403178 G/T cg21252483 chr19:49399788 TULP2 -0.42 -5.83 -0.46 4.55e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs28595532 0.920 rs55985953 chr4:119764971 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs10089 0.953 rs3805615 chr5:127519049 A/G cg19767477 chr5:127420684 SLC12A2 -0.44 -4.56 -0.38 1.2e-5 Ileal carcinoids; TGCT cis rs2295359 0.892 rs4655686 chr1:67638004 T/A cg12940439 chr1:67600707 NA 0.58 5.91 0.47 3.09e-8 Psoriasis; TGCT cis rs10782582 0.609 rs1796815 chr1:76396793 T/G cg03433033 chr1:76189801 ACADM -0.5 -4.9 -0.4 2.9e-6 Daytime sleep phenotypes; TGCT cis rs9653442 0.593 rs4851273 chr2:100848321 A/G cg07810366 chr2:100720526 AFF3 -0.38 -5.55 -0.45 1.63e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4919694 0.611 rs7091462 chr10:104948615 C/T cg04362960 chr10:104952993 NT5C2 0.97 6.81 0.52 3.82e-10 Arsenic metabolism; TGCT cis rs1669338 0.588 rs3864050 chr3:3186769 T/C cg16797762 chr3:3221439 CRBN -0.89 -5.67 -0.45 9.6e-8 White matter integrity; TGCT cis rs12477438 0.520 rs2964969 chr2:99782811 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs1862618 0.853 rs33325 chr5:56142547 G/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs7909074 1.000 rs6593447 chr10:45400235 G/A cg04218760 chr10:45406644 TMEM72 -0.27 -5.31 -0.43 4.88e-7 Mean corpuscular volume; TGCT cis rs57994353 0.566 rs10870160 chr9:139312996 C/T cg13741927 chr9:139327495 INPP5E -0.24 -5.65 -0.45 1.02e-7 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs758129 0.501 rs2529927 chr15:89877527 G/A cg24365117 chr15:89879190 POLG 0.34 4.64 0.38 8.68e-6 Schizophrenia; TGCT cis rs6920965 0.507 rs7754833 chr6:126190894 A/G cg05901451 chr6:126070800 HEY2 -0.67 -6.53 -0.51 1.51e-9 High light scatter reticulocyte count; TGCT cis rs73198271 1.000 rs4841031 chr8:8607395 G/A ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs514406 0.679 rs12563825 chr1:53238324 G/T cg16325326 chr1:53192061 ZYG11B -0.6 -6.74 -0.52 5.43e-10 Monocyte count; TGCT cis rs709400 0.859 rs7154948 chr14:104022944 C/T cg26031613 chr14:104095156 KLC1 1.17 15.98 0.82 6.61e-32 Body mass index; TGCT cis rs394563 0.559 rs7752555 chr6:149671116 A/G cg03678062 chr6:149772716 ZC3H12D 0.38 4.83 0.4 3.94e-6 Dupuytren's disease; TGCT cis rs10197940 0.550 rs77233070 chr2:152416477 G/A cg19508488 chr2:152266495 RIF1 0.65 5.69 0.45 8.81e-8 Lung cancer; TGCT cis rs74233809 1.000 rs5011520 chr10:104697516 G/A cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs13191362 0.507 rs2849525 chr6:163126652 A/C cg06582575 chr6:163149167 PACRG;PARK2 -0.59 -5.75 -0.46 6.6e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7809950 0.678 rs77395658 chr7:107000651 G/A cg23024343 chr7:107201750 COG5 -0.43 -5.85 -0.47 4.12e-8 Coronary artery disease; TGCT cis rs2836950 0.501 rs4818018 chr21:40694072 C/T cg06238570 chr21:40685208 BRWD1 -0.62 -6.32 -0.49 4.19e-9 Menarche (age at onset); TGCT trans rs561341 0.700 rs6505266 chr17:30225813 G/A cg20587970 chr11:113659929 NA -0.59 -8.98 -0.63 3.73e-15 Hip circumference adjusted for BMI; TGCT cis rs7843479 0.601 rs878873 chr8:21834581 T/C cg17168535 chr8:21777572 XPO7 0.8 8.11 0.59 4.09e-13 Mean corpuscular volume; TGCT cis rs6545883 0.862 rs11691734 chr2:61702466 C/T cg15711740 chr2:61764176 XPO1 -0.53 -4.74 -0.39 5.82e-6 Tuberculosis; TGCT trans rs1814175 0.817 rs10769617 chr11:49810421 G/A cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs7223966 1.000 rs8080211 chr17:61729882 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.51 0.38 1.49e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs807669 0.835 rs698423 chr22:19197896 T/C cg02655711 chr22:19163373 SLC25A1 0.39 8.65 0.61 2.23e-14 Metabolite levels; TGCT cis rs10504229 0.813 rs6999878 chr8:58197243 C/G cg22535103 chr8:58192502 C8orf71 -0.39 -4.94 -0.41 2.47e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs1030730 chr2:26284143 T/C cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs6988636 1.000 rs16898095 chr8:124193523 T/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs62064224 0.589 rs9903650 chr17:30689370 T/A cg18200150 chr17:30822561 MYO1D 0.39 4.7 0.39 6.77e-6 Schizophrenia; TGCT cis rs17473412 0.784 rs115433169 chr5:122702575 A/T cg15125798 chr5:122621645 NA -0.57 -4.83 -0.4 3.88e-6 Total body bone mineral density; TGCT cis rs7412746 0.611 rs111842513 chr1:150712926 G/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.53 0.38 1.37e-5 Melanoma; TGCT cis rs806215 1.000 rs806219 chr7:127240094 A/C cg25922125 chr7:127225783 GCC1 0.55 5.66 0.45 9.96e-8 Type 2 diabetes; TGCT cis rs3796352 1.000 rs4478072 chr3:53106125 G/T cg15956490 chr3:53032818 SFMBT1 0.57 6.59 0.51 1.13e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1475911 1.000 rs1475911 chr21:43513480 A/C cg24372256 chr21:43528868 UMODL1;C21orf128 -0.28 -5.12 -0.42 1.15e-6 IgG glycosylation; TGCT cis rs1461503 0.932 rs10790542 chr11:122838243 C/T cg27398637 chr11:122830231 C11orf63 -0.43 -5.32 -0.43 4.69e-7 Menarche (age at onset); TGCT cis rs921968 0.541 rs3770213 chr2:219508372 A/T cg02176678 chr2:219576539 TTLL4 -0.5 -6.98 -0.53 1.59e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs9467773 1.000 rs6903973 chr6:26499942 C/A cg05738196 chr6:26577821 NA 0.87 12.41 0.74 1.7e-23 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs7663924 chr4:99037679 A/G cg18180107 chr4:99064573 C4orf37 -0.55 -5.12 -0.42 1.15e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10493773 1.000 rs2274738 chr1:86119898 A/G cg17807903 chr1:86174739 ZNHIT6 -0.37 -4.69 -0.39 7.01e-6 Urate levels in overweight individuals; TGCT cis rs13108904 0.846 rs4045131 chr4:1228797 A/G cg05665937 chr4:1216051 CTBP1 0.24 4.73 0.39 6.09e-6 Obesity-related traits; TGCT cis rs7949030 0.626 rs7943191 chr11:62328551 A/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.42 0.65 3.17e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs116095464 0.558 rs10056628 chr5:279512 G/A cg22857025 chr5:266934 NA -0.35 -6.87 -0.53 2.7e-10 Breast cancer; TGCT cis rs28595532 1.000 rs41455648 chr4:119718030 A/G cg11846333 chr4:119757529 SEC24D 0.92 4.81 0.4 4.21e-6 Cannabis dependence symptom count; TGCT cis rs1153858 1.000 rs2467864 chr15:45641098 C/T cg14582100 chr15:45693742 SPATA5L1 -0.49 -5.88 -0.47 3.51e-8 Homoarginine levels; TGCT cis rs9325144 0.581 rs2653758 chr12:38946233 G/T cg26384229 chr12:38710491 ALG10B -0.61 -6.21 -0.49 7.5e-9 Morning vs. evening chronotype; TGCT cis rs765787 0.530 rs12323957 chr15:45490773 C/T cg24006582 chr15:45444508 DUOX1 0.25 5.33 0.43 4.48e-7 Uric acid levels; TGCT cis rs3892630 0.818 rs80137870 chr19:33182750 C/T cg22980127 chr19:33182716 NUDT19 0.72 5.11 0.42 1.16e-6 Red blood cell traits; TGCT cis rs7659604 1.000 rs6823488 chr4:122664819 A/G cg06713675 chr4:122721982 EXOSC9 -0.38 -4.66 -0.39 7.88e-6 Type 2 diabetes; TGCT cis rs4654899 1.000 rs6426659 chr1:21361302 G/A cg01072550 chr1:21505969 NA -0.49 -7.87 -0.58 1.47e-12 Superior frontal gyrus grey matter volume; TGCT cis rs6088580 0.634 rs6087577 chr20:32955423 C/T cg06115741 chr20:33292138 TP53INP2 0.51 4.53 0.38 1.35e-5 Glomerular filtration rate (creatinine); TGCT cis rs12477438 0.765 rs62154638 chr2:99639584 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs7666738 0.830 rs10021709 chr4:99030587 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9291683 0.620 rs717615 chr4:10104670 C/T cg11266682 chr4:10021025 SLC2A9 0.48 5.65 0.45 1.04e-7 Bone mineral density; TGCT cis rs1784581 0.651 rs1784593 chr6:162386096 A/T cg17173639 chr6:162384350 PARK2 -0.47 -8.09 -0.59 4.55e-13 Itch intensity from mosquito bite; TGCT cis rs13401104 0.680 rs72620813 chr2:237146225 C/T cg19324714 chr2:237145437 ASB18 0.48 5.05 0.41 1.57e-6 Educational attainment; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg00024416 chr22:24240387 NA 0.25 4.74 0.39 5.74e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs736408 0.609 rs62255396 chr3:52782839 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -5.0 -0.41 1.92e-6 Bipolar disorder; TGCT cis rs13191362 0.507 rs1954810 chr6:163061749 C/T cg21926612 chr6:163149169 PACRG;PARK2 -0.61 -5.52 -0.44 1.91e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7666738 0.830 rs3907021 chr4:99038668 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg11644478 chr21:40555479 PSMG1 -0.53 -4.57 -0.38 1.17e-5 Cognitive function; TGCT cis rs7267979 0.565 rs6107060 chr20:25592476 C/G cg03522245 chr20:25566470 NINL 0.44 4.71 0.39 6.4e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10504229 0.683 rs72650847 chr8:58136825 C/T cg08219700 chr8:58056026 NA 0.38 4.69 0.39 6.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs6540559 0.605 rs3753518 chr1:209977964 G/C cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg05215272 chr17:6899095 ALOX12 0.57 6.79 0.52 4.04e-10 Tonsillectomy; TGCT cis rs9583531 0.714 rs79483970 chr13:111342298 G/A cg15747390 chr13:111297551 CARS2 0.86 5.86 0.47 3.9e-8 Coronary artery disease; TGCT cis rs875971 0.755 rs76288834 chr7:66069802 G/A cg11764359 chr7:65958608 NA -0.57 -5.2 -0.42 8.06e-7 Aortic root size; TGCT cis rs6952808 0.756 rs4719311 chr7:1881813 C/T cg22963979 chr7:1858916 MAD1L1 -0.38 -5.89 -0.47 3.35e-8 Bipolar disorder and schizophrenia; TGCT cis rs921968 0.509 rs7571743 chr2:219352572 C/T cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg26818010 chr10:134567672 INPP5A -0.35 -4.77 -0.39 5.13e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11247915 0.540 rs72649368 chr1:26675018 G/T cg23732845 chr1:26663426 AIM1L -0.37 -4.66 -0.39 8.11e-6 Obesity-related traits; TGCT cis rs11190604 1.000 rs4919472 chr10:102315864 T/A cg16342193 chr10:102329863 NA -0.39 -4.95 -0.41 2.35e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28595532 0.920 rs116607127 chr4:119731072 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs9457247 0.534 rs4710154 chr6:167394634 A/T cg23791538 chr6:167370224 RNASET2 0.63 6.27 0.49 5.55e-9 Crohn's disease; TGCT cis rs6762477 0.748 rs11714286 chr3:50185508 G/A cg15335139 chr3:50242325 SLC38A3 -0.26 -4.83 -0.4 3.94e-6 Menarche (age at onset); TGCT cis rs244731 0.920 rs244707 chr5:176555636 A/T cg16006841 chr5:176797999 RGS14 0.53 6.5 0.5 1.76e-9 Urate levels in lean individuals; TGCT cis rs4862750 0.872 rs7672831 chr4:187898882 C/T cg03452623 chr4:187889614 NA -0.34 -4.94 -0.41 2.46e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs858239 0.539 rs4294098 chr7:23185995 G/A cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs9308731 0.583 rs6726007 chr2:111932122 A/T cg04202892 chr2:111875749 ACOXL 0.46 5.14 0.42 1.02e-6 Chronic lymphocytic leukemia; TGCT cis rs6684514 1.000 rs12117947 chr1:156244058 A/T cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2729354 0.768 rs2729384 chr11:57258617 T/C cg24343310 chr11:57249947 NA 0.29 4.65 0.39 8.49e-6 Blood protein levels; TGCT cis rs10504229 0.906 rs72650894 chr8:58179734 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6964587 1.000 rs13230588 chr7:91615427 C/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6074578 0.679 rs6086352 chr20:140695 C/T cg16931068 chr20:139680 DEFB127 -0.28 -4.85 -0.4 3.62e-6 Hirschsprung disease; TGCT cis rs2243480 0.901 rs2949697 chr7:65464236 A/G cg20637647 chr7:64974828 NA 0.99 5.54 0.45 1.71e-7 Diabetic kidney disease; TGCT cis rs7208859 0.673 rs999797 chr17:29159329 G/A cg14008862 chr17:28927542 LRRC37B2 0.72 4.67 0.39 7.77e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9560113 0.550 rs1163632 chr13:112231530 T/C cg10483660 chr13:112241077 NA -0.31 -4.9 -0.4 2.91e-6 Menarche (age at onset); TGCT cis rs35306767 0.953 rs10904581 chr10:964685 A/T cg20503657 chr10:835505 NA 0.65 9.54 0.65 1.66e-16 Eosinophil percentage of granulocytes; TGCT cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg05985448 chr10:134359359 INPP5A 0.23 5.03 0.41 1.68e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs28386778 0.897 rs894407 chr17:61901641 T/C cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs9790314 0.846 rs9834659 chr3:160980947 A/C cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs3785574 0.650 rs7406102 chr17:62004749 G/A cg11494091 chr17:61959527 GH2 -0.44 -7.54 -0.56 8.47e-12 Height; TGCT cis rs10992471 0.580 rs7852698 chr9:95396409 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -4.65 -0.39 8.53e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs763014 0.966 rs12935215 chr16:670605 T/C cg07343612 chr16:622815 PIGQ -0.42 -8.4 -0.6 8.47e-14 Height; TGCT cis rs7208859 0.623 rs55638872 chr17:29149552 G/C cg14008862 chr17:28927542 LRRC37B2 0.8 4.73 0.39 6.11e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7010267 0.570 rs2326192 chr8:120028855 C/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs259282 0.628 rs35946544 chr19:33109983 C/T cg26639809 chr19:33781782 NA 0.24 4.79 0.4 4.7e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs34412187 chr4:99010454 A/G cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4455778 0.724 rs993871 chr7:48993937 C/T cg26309511 chr7:48887640 NA 0.5 6.13 0.48 1.07e-8 Lung cancer in never smokers; TGCT cis rs1577917 0.876 rs66986937 chr6:86532191 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.46 -0.44 2.47e-7 Response to antipsychotic treatment; TGCT cis rs4819052 0.851 rs8127834 chr21:46696109 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.78 7.16 0.54 6.12e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs79057730 0.527 rs34519158 chr7:811114 G/A cg11064039 chr7:766100 PRKAR1B;HEATR2 0.74 5.59 0.45 1.36e-7 Initial pursuit acceleration; TGCT cis rs2072499 0.900 rs2248080 chr1:156195971 T/A cg25208724 chr1:156163844 SLC25A44 1.11 12.68 0.75 3.79e-24 Testicular germ cell tumor; TGCT cis rs9436747 0.641 rs11208676 chr1:66048123 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.72 0.39 6.28e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7945705 0.747 rs1123936 chr11:9003306 A/G cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -4.95 -0.41 2.38e-6 Hemoglobin concentration; TGCT cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs12541335 0.507 rs9644047 chr8:22158670 T/A cg02463440 chr8:22132932 PIWIL2 0.25 4.82 0.4 4.18e-6 Hypertriglyceridemia; TGCT cis rs9788682 0.624 rs518425 chr15:78883813 A/G cg24631222 chr15:78858424 CHRNA5 0.61 4.8 0.4 4.48e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs875971 0.861 rs801215 chr7:66011938 A/T cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg19723775 chr5:179050963 HNRNPH1 0.59 5.85 0.46 4.19e-8 Lung cancer; TGCT cis rs7000551 0.505 rs13258195 chr8:22227271 A/G cg12081754 chr8:22256438 SLC39A14 -0.38 -5.68 -0.45 8.99e-8 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6977940 0.730 rs11766514 chr7:2896271 C/T cg19731401 chr7:2775893 GNA12 0.37 4.44 0.37 1.98e-5 White matter integrity; TGCT cis rs447921 0.861 rs36119142 chr17:74454336 T/G cg09812376 chr17:74270190 QRICH2 -0.45 -4.65 -0.39 8.4e-6 Mitochondrial DNA levels; TGCT cis rs6061231 0.561 rs67072353 chr20:60940702 G/A cg24112000 chr20:60950667 NA -0.4 -4.71 -0.39 6.44e-6 Colorectal cancer; TGCT cis rs7107174 0.688 rs881361 chr11:78128047 C/G cg12700464 chr11:78128424 GAB2 -0.67 -4.46 -0.37 1.83e-5 Testicular germ cell tumor; TGCT cis rs12497850 0.931 rs4072859 chr3:49032205 G/C cg06212747 chr3:49208901 KLHDC8B 0.61 5.51 0.44 1.95e-7 Parkinson's disease; TGCT cis rs1005277 0.602 rs2504142 chr10:38383793 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.2 -0.59 2.5e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1577917 1.000 rs35385043 chr6:86648546 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.05 -0.41 1.57e-6 Response to antipsychotic treatment; TGCT cis rs854572 0.600 rs854570 chr7:94952692 C/A cg04155289 chr7:94953770 PON1 0.36 6.06 0.48 1.51e-8 Paraoxonase activity; TGCT cis rs1008375 0.931 rs2315558 chr4:17674558 C/A cg10189774 chr4:17578691 LAP3 0.57 5.25 0.43 6.37e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9467773 0.649 rs2145318 chr6:26496603 T/A cg15659132 chr6:26577336 NA 0.64 6.98 0.53 1.59e-10 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.652 rs11513964 chr12:37998214 C/G cg13010199 chr12:38710504 ALG10B 0.65 5.22 0.42 7.4e-7 Bladder cancer; TGCT cis rs1005277 0.522 rs289645 chr10:37943642 T/C cg25427524 chr10:38739819 LOC399744 -0.36 -7.18 -0.54 5.79e-11 Extrinsic epigenetic age acceleration; TGCT cis rs597539 0.652 rs613128 chr11:68638058 G/T cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11676348 0.846 rs7594532 chr2:219008000 T/C cg00012203 chr2:219082015 ARPC2 -0.52 -4.99 -0.41 1.99e-6 Ulcerative colitis; TGCT cis rs13040088 0.872 rs2295481 chr20:61574727 C/T cg23096297 chr20:61557774 DIDO1 1.18 9.71 0.66 6.5e-17 Menopause (age at onset); TGCT cis rs9393692 0.645 rs28446029 chr6:26305801 C/G cg13736514 chr6:26305472 NA -0.45 -6.67 -0.51 7.52e-10 Educational attainment; TGCT cis rs11809207 1.000 rs11247867 chr1:26517891 C/T cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs74181299 0.892 rs2249105 chr2:65287896 C/T cg05010058 chr2:65284262 CEP68 -0.42 -4.79 -0.4 4.66e-6 Pulse pressure; TGCT cis rs7267979 0.899 rs2179459 chr20:25456141 C/A cg16686733 chr20:25566563 NINL 0.52 5.24 0.43 6.64e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6460942 0.908 rs967126 chr7:12237300 G/C cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg09060608 chr5:178986726 RUFY1 0.58 6.88 0.53 2.61e-10 Lung cancer; TGCT cis rs12220238 1.000 rs111704178 chr10:75957251 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.78 0.57 2.42e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9787249 0.957 rs7547787 chr1:40220806 C/T cg24920358 chr1:40204285 PPIE 0.58 10.68 0.69 2.74e-19 Blood protein levels; TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs11718455 0.960 rs13059547 chr3:44004492 G/A cg08738300 chr3:44038990 NA 0.86 6.55 0.51 1.4e-9 Coronary artery disease; TGCT cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs8067545 0.750 rs4925069 chr17:19953531 C/G cg13482628 chr17:19912719 NA 0.53 4.58 0.38 1.1e-5 Schizophrenia; TGCT cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs477895 0.653 rs11606544 chr11:63896901 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 6.06 0.48 1.51e-8 Mean platelet volume; TGCT trans rs208520 0.661 rs1100950 chr6:66827285 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.99 -10.56 -0.69 5.53e-19 Exhaled nitric oxide output; TGCT cis rs72781680 0.716 rs7564732 chr2:24034178 C/T cg08917208 chr2:24149416 ATAD2B 0.81 5.13 0.42 1.1e-6 Lymphocyte counts; TGCT cis rs2836950 0.545 rs8132143 chr21:40584258 A/T cg06238570 chr21:40685208 BRWD1 -0.61 -6.35 -0.5 3.7e-9 Menarche (age at onset); TGCT cis rs79387448 0.745 rs72995652 chr2:103171651 C/A cg09003973 chr2:102972529 NA 0.95 6.15 0.48 9.95e-9 Gut microbiota (bacterial taxa); TGCT cis rs459571 0.959 rs2073818 chr9:136918662 C/A cg13789015 chr9:136890014 NCRNA00094 0.39 6.83 0.52 3.45e-10 Platelet distribution width; TGCT cis rs2153535 0.601 rs4140584 chr6:8540614 C/G cg07606381 chr6:8435919 SLC35B3 -0.54 -4.97 -0.41 2.22e-6 Motion sickness; TGCT cis rs6860806 0.507 rs272872 chr5:131675864 C/T cg24060327 chr5:131705240 SLC22A5 0.72 8.0 0.58 7.65e-13 Breast cancer; TGCT cis rs5769765 0.542 rs5769751 chr22:50242733 T/G cg02269571 chr22:50332266 NA 0.35 4.57 0.38 1.18e-5 Schizophrenia; TGCT cis rs651907 0.535 rs13094911 chr3:101519021 T/C cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs4665809 1.000 rs1470097 chr2:26312840 A/G cg25036284 chr2:26402008 FAM59B -0.56 -4.88 -0.4 3.2e-6 Gut microbiome composition (summer); TGCT cis rs644148 0.902 rs12982159 chr19:44964300 C/T cg15540054 chr19:45004280 ZNF180 -0.56 -5.12 -0.42 1.12e-6 Personality dimensions; TGCT cis rs2439831 0.850 rs16950562 chr15:44036364 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs11190604 0.767 rs7076606 chr10:102192267 T/C cg16342193 chr10:102329863 NA -0.38 -5.0 -0.41 1.93e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs832540 0.931 rs832399 chr5:56222358 A/T cg24531977 chr5:56204891 C5orf35 -0.54 -5.51 -0.44 2.02e-7 Coronary artery disease; TGCT cis rs1008375 0.898 rs61047804 chr4:17593965 G/A cg18681998 chr4:17616180 MED28 1.0 10.01 0.67 1.2e-17 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4851266 0.898 rs13010010 chr2:100852734 C/T cg07810366 chr2:100720526 AFF3 -0.38 -5.39 -0.44 3.48e-7 Educational attainment; TGCT cis rs2721195 0.614 rs12719778 chr8:145879883 T/C cg15857475 chr8:145742913 RECQL4;LRRC14 0.93 9.9 0.66 2.19e-17 Age at first birth; TGCT cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2777491 0.507 rs11854081 chr15:41646398 C/T cg18705301 chr15:41695430 NDUFAF1 -0.93 -15.88 -0.82 1.15e-31 Ulcerative colitis; TGCT cis rs72781680 1.000 rs72796327 chr2:24140372 T/C cg08917208 chr2:24149416 ATAD2B 0.8 4.94 0.41 2.47e-6 Lymphocyte counts; TGCT cis rs7119 0.717 rs12916642 chr15:77818426 G/T cg27398640 chr15:77910606 LINGO1 -0.26 -4.66 -0.39 7.98e-6 Type 2 diabetes; TGCT cis rs514406 0.505 rs395169 chr1:53174071 G/A cg01802117 chr1:53393560 SCP2 -0.39 -4.6 -0.38 1.02e-5 Monocyte count; TGCT cis rs9318086 0.663 rs2312295 chr13:24457744 A/T cg25267304 chr13:24462978 PCOTH;MIPEP 0.81 9.02 0.63 2.85e-15 Myopia (pathological); TGCT cis rs7666738 0.753 rs35194639 chr4:99053819 G/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs478304 0.934 rs669742 chr11:65501291 C/T cg17480646 chr11:65405466 SIPA1 0.43 5.35 0.43 4.18e-7 Acne (severe); TGCT cis rs858239 0.600 rs2072368 chr7:23146112 C/T cg05602783 chr7:23145260 KLHL7 -0.67 -5.7 -0.46 8.23e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs7119038 0.629 rs11216995 chr11:118603526 G/A cg19308663 chr11:118741387 NA 0.23 4.49 0.37 1.62e-5 Sjögren's syndrome; TGCT cis rs6076065 0.513 rs13037787 chr20:23425811 C/T cg11657817 chr20:23433608 CST11 0.29 4.75 0.39 5.44e-6 Facial morphology (factor 15, philtrum width); TGCT cis rs9914988 0.943 rs4313850 chr17:27080768 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.01 -0.41 1.8e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs9916302 0.904 rs2024073 chr17:37471330 T/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs250677 0.687 rs250672 chr5:148446110 A/G cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg08645402 chr16:4508243 NA 0.18 5.18 0.42 8.72e-7 Schizophrenia; TGCT cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg12310025 chr6:25882481 NA 0.66 5.99 0.47 2.11e-8 Intelligence (multi-trait analysis); TGCT cis rs7654585 0.886 rs1466281 chr4:25936665 G/A cg10409131 chr4:25915609 C4orf52 0.71 6.64 0.51 8.9e-10 Obesity-related traits; TGCT cis rs12368653 1.000 rs12368653 chr12:58133256 A/G cg12615879 chr12:58013172 SLC26A10 -0.47 -5.8 -0.46 5.07e-8 Multiple sclerosis; TGCT cis rs6546537 1.000 rs2048256 chr2:69847357 G/C cg10773587 chr2:69614142 GFPT1 -0.71 -6.21 -0.49 7.16e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs16958440 0.867 rs75901436 chr18:44689644 C/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs769267 0.895 rs2965183 chr19:19545696 G/A cg03709012 chr19:19516395 GATAD2A 0.75 6.51 0.5 1.71e-9 Tonsillectomy; TGCT cis rs78487399 0.808 rs75135247 chr2:43699399 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.52 -0.38 1.42e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4304924 0.500 rs2281856 chr13:79207644 C/T cg01819759 chr13:79234251 RNF219 -0.78 -6.66 -0.51 8.13e-10 Large artery stroke; TGCT cis rs886126 0.950 rs6490029 chr12:111698457 G/A cg10833066 chr12:111807467 FAM109A 0.35 5.45 0.44 2.59e-7 Coronary heart disease; TGCT cis rs910316 1.000 rs1043674 chr14:75549370 T/C cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT cis rs10504229 0.817 rs78138632 chr8:58191341 G/T cg22535103 chr8:58192502 C8orf71 -0.46 -5.16 -0.42 9.68e-7 Developmental language disorder (linguistic errors); TGCT cis rs7833790 0.750 rs10108955 chr8:82690644 C/T cg17211192 chr8:82754475 SNX16 -1.04 -8.46 -0.6 6.42e-14 Diastolic blood pressure; TGCT cis rs6088580 0.634 rs6088471 chr20:32932643 C/A cg08999081 chr20:33150536 PIGU -0.26 -4.98 -0.41 2.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.91 0.4 2.75e-6 Electroencephalogram traits; TGCT cis rs10927875 0.518 rs732286 chr1:16344360 A/G cg21385522 chr1:16154831 NA 0.47 4.85 0.4 3.57e-6 Dilated cardiomyopathy; TGCT cis rs6500602 0.673 rs4786513 chr16:4576423 T/C cg08645402 chr16:4508243 NA 0.22 5.58 0.45 1.43e-7 Schizophrenia; TGCT cis rs765787 0.530 rs12442533 chr15:45529631 G/C cg24006582 chr15:45444508 DUOX1 0.24 5.3 0.43 5.17e-7 Uric acid levels; TGCT cis rs7681440 0.904 rs6816469 chr4:90772885 G/C cg20003494 chr4:90757398 SNCA -0.59 -5.52 -0.44 1.9e-7 Dementia with Lewy bodies; TGCT cis rs4622507 0.819 rs4784455 chr16:55054810 T/A cg04853843 chr16:55358461 IRX6 -0.54 -4.93 -0.4 2.59e-6 Social communication problems; TGCT trans rs916888 0.821 rs199506 chr17:44859031 A/G cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1775715 0.707 rs1541261 chr10:32179523 G/A cg14930904 chr10:32216787 ARHGAP12 0.53 5.03 0.41 1.66e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs6866344 0.697 rs62392833 chr5:178135452 T/A cg03877680 chr5:178157825 ZNF354A 0.74 5.98 0.47 2.16e-8 Neutrophil percentage of white cells; TGCT cis rs1008375 0.966 rs3775925 chr4:17588437 A/G cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2032447 0.670 rs198815 chr6:26127271 A/G cg03264133 chr6:25882463 NA 0.5 4.58 0.38 1.13e-5 Intelligence (multi-trait analysis); TGCT cis rs67478160 0.643 rs12434686 chr14:104316033 C/T cg26031613 chr14:104095156 KLC1 0.67 6.93 0.53 2e-10 Schizophrenia; TGCT cis rs694739 0.628 rs508168 chr11:64135435 G/A cg23796481 chr11:64053134 BAD;GPR137 0.64 6.62 0.51 9.49e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs2180341 0.781 rs877102 chr6:127587086 T/C cg27446573 chr6:127587934 RNF146 0.91 8.5 0.61 5.12e-14 Breast cancer; TGCT cis rs11711311 0.736 rs13320940 chr3:113400954 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.69 -6.08 -0.48 1.37e-8 IgG glycosylation; TGCT cis rs4700695 0.841 rs433773 chr5:65309609 G/C cg21114390 chr5:65439923 SFRS12 0.6 4.47 0.37 1.71e-5 Facial morphology (factor 19); TGCT cis rs6754311 0.731 rs12615624 chr2:136721603 A/G cg07169764 chr2:136633963 MCM6 0.69 6.43 0.5 2.49e-9 Mosquito bite size; TGCT cis rs2594989 0.943 rs2443713 chr3:11537540 T/G cg00170343 chr3:11313890 ATG7 0.65 4.66 0.39 8e-6 Circulating chemerin levels; TGCT cis rs7666738 0.830 rs62318471 chr4:98925848 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.85 0.46 4.16e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs1814175 0.817 rs10839358 chr11:49770972 G/A cg03929089 chr4:120376271 NA -0.69 -8.17 -0.59 3.03e-13 Height; TGCT cis rs5167 0.566 rs60876330 chr19:45488133 C/T cg09555818 chr19:45449301 APOC2 0.23 4.52 0.38 1.45e-5 Blood protein levels; TGCT cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg13409248 chr3:40428643 ENTPD3 0.59 4.62 0.38 9.58e-6 Renal cell carcinoma; TGCT cis rs10779751 0.734 rs2748877 chr1:11129437 T/C cg08854313 chr1:11322531 MTOR 0.82 7.04 0.53 1.19e-10 Body mass index; TGCT cis rs6063312 0.667 rs9679994 chr20:47281853 T/C cg18078177 chr20:47281410 PREX1 0.39 4.98 0.41 2.05e-6 Tonometry; TGCT cis rs8177253 0.931 rs8177256 chr3:133480276 G/T cg16414030 chr3:133502952 NA -0.61 -9.65 -0.66 8.74e-17 Iron status biomarkers; TGCT cis rs28595532 0.920 rs56252481 chr4:119754023 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs854765 0.619 rs4561528 chr17:17979099 C/T cg09796270 chr17:17721594 SREBF1 0.23 4.63 0.38 9e-6 Total body bone mineral density; TGCT cis rs9796 0.689 rs692511 chr15:41446252 A/C cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.88 -0.53 2.57e-10 Menopause (age at onset); TGCT cis rs1729951 0.575 rs2163896 chr3:136691177 G/A cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs34014631 1.000 rs75905271 chr10:103686236 T/C cg22630918 chr10:102748988 C10orf2 0.42 4.78 0.39 4.86e-6 Coronary artery calcification; TGCT cis rs4563143 0.675 rs73029049 chr19:29275534 C/A cg03161606 chr19:29218774 NA 0.6 5.79 0.46 5.33e-8 Methadone dose in opioid dependence; TGCT cis rs12497850 0.863 rs4858799 chr3:48728204 G/C cg07636037 chr3:49044803 WDR6 0.92 10.34 0.68 1.91e-18 Parkinson's disease; TGCT cis rs4663866 1.000 rs13026475 chr2:239178455 T/C cg17283117 chr2:239148619 HES6 0.98 4.52 0.38 1.42e-5 Irritable bowel syndrome; TGCT cis rs4786125 0.706 rs8062094 chr16:6902585 A/G cg03623568 chr16:6915990 A2BP1 -0.44 -6.4 -0.5 2.85e-9 Heart rate variability traits (SDNN); TGCT cis rs7027203 0.717 rs7869328 chr9:96588782 A/G cg14396892 chr9:96623032 NA -0.28 -5.86 -0.47 3.9e-8 DNA methylation (variation); TGCT cis rs7043114 0.544 rs4302908 chr9:95321641 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.25 -0.43 6.27e-7 Height; TGCT cis rs514406 0.505 rs269289 chr1:53167151 A/C cg16325326 chr1:53192061 ZYG11B 0.83 11.14 0.71 2.12e-20 Monocyte count; TGCT cis rs6728642 0.708 rs115507803 chr2:97752054 T/C cg26665480 chr2:98280029 ACTR1B -0.96 -5.36 -0.43 3.91e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs6088590 0.735 rs2273684 chr20:33529766 G/T cg08999081 chr20:33150536 PIGU -0.25 -4.59 -0.38 1.07e-5 Coronary artery disease; TGCT cis rs2302045 1.000 rs2270044 chr2:242056924 A/G cg04553960 chr2:241721320 KIF1A -0.75 -4.76 -0.39 5.19e-6 Pharmacokinetics of antipsychotic drugs in severe mental disorder (concentration drug ratio); TGCT cis rs644799 0.544 rs1150360 chr11:95512060 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.55 5.67 0.45 9.5e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs3015497 0.626 rs7150204 chr14:51137355 T/C cg04730355 chr14:51134070 SAV1 -0.61 -5.84 -0.46 4.22e-8 Mean platelet volume; TGCT cis rs6665290 0.901 rs61834001 chr1:227197411 C/T cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs2243480 0.901 rs73142137 chr7:65343442 A/T cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs28386778 0.897 rs6504176 chr17:61811920 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs501916 0.833 rs59184310 chr15:48050205 A/T cg16110827 chr15:48056943 SEMA6D -0.17 -4.77 -0.39 5.12e-6 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs28595532 0.541 rs114463740 chr4:119763329 C/T cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs3087591 0.959 rs8076441 chr17:29405878 C/T cg24425628 chr17:29625626 OMG;NF1 -0.5 -7.54 -0.56 8.86e-12 Hip circumference; TGCT cis rs2637266 1.000 rs12258924 chr10:78364758 G/A cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs6095298 0.574 rs4428070 chr20:47457735 C/A cg12307787 chr20:48099359 KCNB1 0.42 4.54 0.38 1.32e-5 Intelligence (multi-trait analysis); TGCT cis rs3741151 1.000 rs76764824 chr11:73073580 C/T cg17517138 chr11:73019481 ARHGEF17 0.94 4.71 0.39 6.45e-6 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs9611565 0.921 rs2235846 chr22:41741042 G/C cg06634786 chr22:41940651 POLR3H -0.63 -6.01 -0.47 1.93e-8 Vitiligo; TGCT cis rs4149178 0.656 rs9472032 chr6:43294041 C/A cg12269535 chr6:43142014 SRF 0.58 4.84 0.4 3.72e-6 Urate levels; TGCT cis rs12142240 0.698 rs66575205 chr1:46814092 T/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs875971 0.558 rs4433015 chr7:65639723 A/C cg18876405 chr7:65276391 NA -0.4 -6.12 -0.48 1.11e-8 Aortic root size; TGCT cis rs12049351 0.774 rs4925455 chr1:229623665 T/A cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs9527 0.590 rs1935323 chr10:104877035 T/C cg15744005 chr10:104629667 AS3MT -0.41 -4.8 -0.4 4.46e-6 Arsenic metabolism; TGCT cis rs4478858 0.647 rs12752761 chr1:31710888 T/C cg00250761 chr1:31883323 NA -0.27 -4.89 -0.4 3.11e-6 Alcohol dependence; TGCT cis rs1865760 1.000 rs7770139 chr6:25925823 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.21 0.49 7.42e-9 Height; TGCT cis rs7662987 0.517 rs2851277 chr4:100022910 G/T cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs28386778 0.897 rs2665832 chr17:61912261 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.78 7.35 0.55 2.28e-11 Prudent dietary pattern; TGCT cis rs12421382 1.000 rs12421382 chr11:109378071 C/T cg16359550 chr11:109292809 C11orf87 0.52 5.61 0.45 1.27e-7 Schizophrenia; TGCT cis rs2708977 0.933 rs2708976 chr2:97184532 C/G cg01950434 chr2:97203154 ARID5A -0.69 -6.34 -0.49 3.87e-9 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs72945132 0.882 rs17160753 chr11:70131462 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9926296 0.632 rs9935559 chr16:89800529 C/T cg27121462 chr16:89883253 FANCA -0.54 -5.06 -0.41 1.45e-6 Vitiligo; TGCT cis rs10782582 0.593 rs6673786 chr1:76149637 C/T cg10523679 chr1:76189770 ACADM -0.69 -7.16 -0.54 6.4e-11 Daytime sleep phenotypes; TGCT cis rs2228479 0.571 rs62052183 chr16:89966921 C/A cg06558623 chr16:89946397 TCF25 0.53 6.59 0.51 1.14e-9 Skin colour saturation; TGCT cis rs1008375 0.797 rs6843530 chr4:17593605 G/T cg16339924 chr4:17578868 LAP3 0.81 6.69 0.52 6.75e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13401104 0.587 rs62190972 chr2:237145164 T/C cg19324714 chr2:237145437 ASB18 0.48 5.03 0.41 1.67e-6 Educational attainment; TGCT cis rs9393777 0.513 rs9379893 chr6:26584668 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 0.52 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs2243480 0.901 rs313808 chr7:65499873 T/G cg07424592 chr7:64974309 NA 1.39 8.27 0.6 1.78e-13 Diabetic kidney disease; TGCT cis rs587847 0.737 rs2124972 chr15:37681973 C/T cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.91e-5 Intraocular pressure; TGCT cis rs12497850 0.931 rs7636057 chr3:48992582 C/T cg07636037 chr3:49044803 WDR6 0.96 10.39 0.68 1.45e-18 Parkinson's disease; TGCT cis rs12530845 1.000 rs6979439 chr7:135329004 A/G cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs7428 1.000 rs7428 chr2:85545490 C/T cg24342717 chr2:85555507 TGOLN2 0.39 6.41 0.5 2.72e-9 Ear protrusion; TGCT cis rs9583531 0.527 rs3818496 chr13:111358488 G/A cg24331049 chr13:111365604 ING1 0.74 7.18 0.54 5.77e-11 Coronary artery disease; TGCT cis rs478304 0.903 rs12293022 chr11:65531698 C/T cg27068330 chr11:65405492 SIPA1 0.74 7.41 0.55 1.67e-11 Acne (severe); TGCT cis rs1062177 0.906 rs2964573 chr5:151160122 A/T cg12924095 chr5:151150029 G3BP1 0.35 5.09 0.42 1.31e-6 Preschool internalizing problems; TGCT cis rs6088580 0.634 rs6059824 chr20:33014543 T/C cg08999081 chr20:33150536 PIGU 0.28 5.52 0.44 1.89e-7 Glomerular filtration rate (creatinine); TGCT cis rs295140 0.656 rs3769472 chr2:201193373 G/A cg04283868 chr2:201171347 SPATS2L 0.6 5.81 0.46 4.83e-8 QT interval; TGCT cis rs7666738 0.546 rs6827131 chr4:98744810 C/G cg18180107 chr4:99064573 C4orf37 0.54 4.78 0.39 4.93e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.772 rs10796935 chr1:154891363 G/T cg03351412 chr1:154909251 PMVK 0.53 4.93 0.4 2.6e-6 Prostate cancer; TGCT cis rs939658 0.805 rs12902831 chr15:79433171 G/A cg17916960 chr15:79447300 NA -0.49 -7.41 -0.55 1.73e-11 Refractive error; TGCT cis rs9467773 0.626 rs6935803 chr6:26350495 A/G cg05738196 chr6:26577821 NA -0.63 -6.77 -0.52 4.5e-10 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.867 rs2447211 chr15:43936351 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.73 4.95 0.41 2.38e-6 Lung cancer in ever smokers; TGCT cis rs6840360 0.558 rs11735310 chr4:152287922 T/C cg17479576 chr4:152424074 FAM160A1 -0.45 -4.72 -0.39 6.27e-6 Intelligence (multi-trait analysis); TGCT cis rs12478296 0.892 rs60545379 chr2:243034390 A/T cg06360820 chr2:242988706 NA -0.58 -4.47 -0.37 1.76e-5 Obesity-related traits; TGCT cis rs11785400 0.793 rs7017851 chr8:143722038 G/T cg10596483 chr8:143751796 JRK 0.53 5.09 0.42 1.28e-6 Schizophrenia; TGCT cis rs9660180 0.780 rs12038111 chr1:1703849 T/C cg13866156 chr1:1669148 SLC35E2 -0.24 -5.86 -0.47 4e-8 Body mass index; TGCT cis rs9549260 0.564 rs4941989 chr13:41299687 T/C cg21288729 chr13:41239152 FOXO1 0.94 9.08 0.63 2.07e-15 Red blood cell count; TGCT cis rs8030485 0.690 rs9920235 chr15:79384021 C/T cg17916960 chr15:79447300 NA 0.36 5.02 0.41 1.74e-6 Left ventricle wall thickness; TGCT cis rs6840360 0.615 rs4696097 chr4:152479765 C/T cg17479576 chr4:152424074 FAM160A1 0.7 7.49 0.56 1.14e-11 Intelligence (multi-trait analysis); TGCT cis rs736408 0.562 rs2072390 chr3:52780509 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.03 0.48 1.79e-8 Bipolar disorder; TGCT cis rs2153535 0.580 rs1335641 chr6:8487860 G/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs2730260 0.537 rs3793224 chr7:158876573 G/A cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs904251 0.523 rs2797798 chr6:37481437 C/T cg01843034 chr6:37503916 NA -0.56 -7.56 -0.56 7.84e-12 Cognitive performance; TGCT cis rs4072705 0.605 rs10986358 chr9:127294185 A/C cg13476313 chr9:127244764 NR5A1 0.32 4.73 0.39 6.08e-6 Menarche (age at onset); TGCT cis rs2535633 0.631 rs2581819 chr3:53016552 C/A cg10802521 chr3:52805072 NEK4 0.55 5.88 0.47 3.48e-8 Body mass index; TGCT cis rs6598541 0.505 rs2137680 chr15:99312741 A/G cg18742785 chr15:100270048 LYSMD4 -0.26 -4.55 -0.38 1.25e-5 Urate levels; TGCT cis rs12477438 0.520 rs4851188 chr2:99745898 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT cis rs425277 0.561 rs925906 chr1:2044054 A/C cg03732007 chr1:2071316 PRKCZ -0.26 -5.96 -0.47 2.48e-8 Height; TGCT cis rs1669338 0.588 rs4685612 chr3:3209242 G/T cg16797762 chr3:3221439 CRBN -0.95 -5.68 -0.45 9.17e-8 White matter integrity; TGCT trans rs1814175 0.588 rs10839463 chr11:49971643 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs7412746 0.588 rs10305664 chr1:150839686 A/C cg09365446 chr1:150670422 GOLPH3L 0.35 4.98 0.41 2.11e-6 Melanoma; TGCT cis rs732765 0.648 rs8019391 chr14:75409682 T/C cg06637938 chr14:75390232 RPS6KL1 0.65 5.76 0.46 6.11e-8 Non-small cell lung cancer; TGCT cis rs9393692 0.645 rs766406 chr6:26319588 G/T cg13736514 chr6:26305472 NA -0.47 -6.9 -0.53 2.34e-10 Educational attainment; TGCT cis rs4595586 0.545 rs925828 chr12:39364222 A/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs986417 0.786 rs1254273 chr14:60843581 C/A cg27398547 chr14:60952738 C14orf39 -1.37 -8.31 -0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs2439831 0.850 rs7163245 chr15:43671294 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs3733585 0.673 rs4495037 chr4:9954050 C/G cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7959452 0.868 rs10784774 chr12:69737879 C/T cg11871910 chr12:69753446 YEATS4 -0.68 -7.39 -0.55 1.93e-11 Blood protein levels; TGCT cis rs1008375 1.000 rs2315560 chr4:17677305 C/G cg10189774 chr4:17578691 LAP3 0.53 5.05 0.41 1.52e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6988636 1.000 rs7002021 chr8:124185250 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs8177253 0.511 rs9830001 chr3:133433470 A/G cg16414030 chr3:133502952 NA 0.44 5.8 0.46 5.09e-8 Iron status biomarkers; TGCT cis rs7017914 0.905 rs4074909 chr8:71955827 G/A cg23757474 chr8:71581111 LACTB2;XKR9 0.55 5.11 0.42 1.17e-6 Bone mineral density; TGCT trans rs797680 0.856 rs10874762 chr1:93639101 T/G cg27528825 chr2:159282178 CCDC148 -0.35 -6.83 -0.52 3.39e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg20999797 chr1:1681921 NA 0.19 4.87 0.4 3.26e-6 Body mass index; TGCT cis rs453301 0.653 rs1045529 chr8:8890098 A/G cg15556689 chr8:8085844 FLJ10661 -0.78 -7.27 -0.55 3.52e-11 Joint mobility (Beighton score); TGCT cis rs2013441 1.000 rs2703804 chr17:20107195 T/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs1200821 0.535 rs1208783 chr10:37767467 A/G cg25427524 chr10:38739819 LOC399744 -0.29 -5.26 -0.43 5.99e-7 Hemostatic factors and hematological phenotypes; TGCT cis rs6815814 0.950 rs73236632 chr4:38836071 G/A cg02016764 chr4:38805732 TLR1 -0.33 -4.95 -0.41 2.39e-6 Breast cancer; TGCT cis rs929354 0.772 rs1182365 chr7:157017255 A/T cg05182265 chr7:156933206 UBE3C 0.4 9.08 0.63 2.11e-15 Body mass index; TGCT cis rs7833790 0.777 rs10958042 chr8:82678393 G/T cg27398817 chr8:82754497 SNX16 -0.82 -5.97 -0.47 2.29e-8 Diastolic blood pressure; TGCT cis rs10504229 0.639 rs35527749 chr8:58128077 G/T cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs7552404 1.000 rs942270 chr1:76177332 G/A cg22875332 chr1:76189707 ACADM 0.78 9.59 0.65 1.27e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs35306767 0.903 rs7074642 chr10:878359 A/G cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs57590327 0.628 rs34439726 chr3:81667241 C/T cg07356753 chr3:81810745 GBE1 -0.61 -4.95 -0.41 2.37e-6 Extraversion; TGCT cis rs6964587 0.967 rs17164315 chr7:91659150 C/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6089829 0.962 rs6062777 chr20:61663748 G/A cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs1800795 0.652 rs7802307 chr7:22766433 T/A cg26061582 chr7:22766209 IL6 0.46 5.91 0.47 3.14e-8 Cerebrospinal fluid clusterin levels in APOEe4- carriers; TGCT cis rs3812049 0.826 rs2409110 chr5:127433047 A/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.64 5.87 0.47 3.81e-8 Lymphocyte counts;Red cell distribution width; TGCT cis rs28386778 0.724 rs35092235 chr17:61944621 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.72 -0.39 6.15e-6 Prudent dietary pattern; TGCT cis rs6570726 1.000 rs444564 chr6:145859795 G/C cg05347473 chr6:146136440 FBXO30 0.5 4.46 0.37 1.82e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs79976124 0.837 rs74327235 chr6:66648353 T/A cg07460842 chr6:66804631 NA 0.58 5.29 0.43 5.33e-7 Type 2 diabetes; TGCT cis rs4711350 0.906 rs943463 chr6:33719877 A/G cg18005901 chr6:33739558 LEMD2 -0.46 -5.04 -0.41 1.62e-6 Schizophrenia; TGCT cis rs1799949 1.000 rs35956818 chr17:41422985 T/C cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs6665290 0.904 rs3738729 chr1:227191227 C/T cg10327440 chr1:227177885 CDC42BPA -1.0 -20.5 -0.88 1.18e-41 Myeloid white cell count; TGCT cis rs2019216 0.542 rs2221893 chr17:21930012 A/G cg22648282 chr17:21454238 C17orf51 -0.59 -5.89 -0.47 3.46e-8 Pelvic organ prolapse; TGCT cis rs3776081 0.600 rs17708682 chr5:149529999 C/T cg18424208 chr5:149546337 CDX1 -0.25 -4.6 -0.38 1.01e-5 Blood protein levels; TGCT cis rs4332037 0.586 rs62442944 chr7:2015047 T/G cg25834613 chr7:1915315 MAD1L1 -0.47 -4.51 -0.38 1.48e-5 Bipolar disorder; TGCT cis rs7607369 0.714 rs55900247 chr2:219618708 T/C cg02176678 chr2:219576539 TTLL4 -0.5 -6.48 -0.5 1.92e-9 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs9916302 0.706 rs9891892 chr17:37479856 A/C cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs3806843 0.576 rs246024 chr5:140333952 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs7666738 0.830 rs60411337 chr4:99046617 T/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs8062405 0.789 rs1968752 chr16:28631585 G/T cg09754948 chr16:28834200 ATXN2L 0.55 4.47 0.37 1.71e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs4689388 0.889 rs10026334 chr4:6294607 G/A cg14416269 chr4:6271139 WFS1 0.37 4.9 0.4 2.95e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs7954584 0.626 rs12809676 chr12:122442381 C/A cg22618164 chr12:122356400 WDR66 0.69 6.32 0.49 4.32e-9 Mean corpuscular volume; TGCT cis rs11626933 1.000 rs7149083 chr14:90754006 G/A cg14092571 chr14:90743983 NA -0.29 -6.02 -0.48 1.86e-8 Gut microbiota (bacterial taxa); TGCT cis rs600231 0.706 rs1111934 chr11:65329392 A/G cg21890820 chr11:65308645 LTBP3 0.39 5.11 0.42 1.19e-6 Bone mineral density; TGCT cis rs6988636 1.000 rs13260318 chr8:124190165 C/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs10464366 0.544 rs1525799 chr7:39153131 C/G cg15212455 chr7:39170539 POU6F2 -0.3 -6.55 -0.51 1.38e-9 IgG glycosylation; TGCT cis rs910316 0.935 rs3742771 chr14:75599647 A/G cg08847533 chr14:75593920 NEK9 0.92 9.91 0.66 2.1e-17 Height; TGCT cis rs796364 0.906 rs1658810 chr2:200816382 C/T cg23649088 chr2:200775458 C2orf69 0.34 4.54 0.38 1.31e-5 Schizophrenia; TGCT cis rs10465746 0.967 rs12757632 chr1:84416408 T/C cg10977910 chr1:84465055 TTLL7 0.66 6.57 0.51 1.27e-9 Obesity-related traits; TGCT cis rs7940866 0.903 rs7942900 chr11:130839244 G/A cg05962950 chr11:130786565 SNX19 0.67 6.57 0.51 1.26e-9 Schizophrenia; TGCT cis rs6964587 0.967 rs10246036 chr7:91558523 G/A cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT cis rs1005277 0.505 rs200910 chr10:38108176 C/T cg13531842 chr10:38383804 ZNF37A -0.39 -4.58 -0.38 1.1e-5 Extrinsic epigenetic age acceleration; TGCT trans rs561341 1.000 rs56362439 chr17:30253140 T/A cg20587970 chr11:113659929 NA -0.91 -10.05 -0.67 9.52e-18 Hip circumference adjusted for BMI; TGCT cis rs7666738 0.830 rs4443293 chr4:99063120 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9581857 0.579 rs3759434 chr13:27997700 A/C cg01674679 chr13:27998804 GTF3A -0.66 -4.6 -0.38 1.01e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs1577917 0.958 rs2084294 chr6:86565943 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs7267979 0.966 rs6037103 chr20:25369095 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10411936 1.000 rs7256818 chr19:16558766 C/A cg19006008 chr19:16999768 F2RL3 -0.27 -4.65 -0.39 8.23e-6 White blood cell count;Multiple sclerosis; TGCT cis rs6840360 0.615 rs2120098 chr4:152457180 T/A cg17479576 chr4:152424074 FAM160A1 -0.73 -8.03 -0.58 6.46e-13 Intelligence (multi-trait analysis); TGCT cis rs11577318 0.853 rs4333841 chr1:26631927 T/C cg04990556 chr1:26633338 UBXN11 -0.63 -5.83 -0.46 4.58e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs6988636 1.000 rs13261021 chr8:124190239 G/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs9536318 0.673 rs7984541 chr13:53510729 T/C cg08567279 chr13:53313529 LECT1 -0.49 -4.47 -0.37 1.73e-5 Airflow obstruction; TGCT cis rs6088590 1.000 rs6087623 chr20:33317662 C/G cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs9911578 0.933 rs2632508 chr17:56533235 G/A cg05425664 chr17:57184151 TRIM37 -0.63 -6.21 -0.49 7.48e-9 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.714 rs2293600 chr3:44599103 G/T cg11003573 chr3:44754125 ZNF502 0.41 4.64 0.38 8.86e-6 Depressive symptoms; TGCT cis rs8078723 0.966 rs7021 chr17:38153875 T/A cg17467752 chr17:38218738 THRA 0.55 5.34 0.43 4.24e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs17534004 1.000 rs34538248 chr13:31468796 A/C cg13251181 chr13:31481184 C13orf33 0.38 4.67 0.39 7.64e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs875971 0.862 rs778724 chr7:65829291 T/C cg11764359 chr7:65958608 NA 0.58 5.31 0.43 4.91e-7 Aortic root size; TGCT cis rs9650657 0.538 rs6984496 chr8:10796093 G/T cg27411982 chr8:10470053 RP1L1 -0.23 -4.68 -0.39 7.46e-6 Neuroticism; TGCT cis rs1878931 0.582 rs27238 chr16:3441223 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.45 -0.5 2.3e-9 Body mass index (adult); TGCT cis rs9300255 0.544 rs1790123 chr12:123659542 C/T cg00376283 chr12:123451042 ABCB9 0.73 5.06 0.41 1.49e-6 Neutrophil percentage of white cells; TGCT cis rs7246657 0.722 rs968073 chr19:38192021 G/A cg18154014 chr19:37997991 ZNF793 -0.72 -5.06 -0.41 1.48e-6 Coronary artery calcification; TGCT cis rs2299587 0.623 rs7816738 chr8:17768482 A/G cg01800426 chr8:17659068 MTUS1 -0.67 -5.67 -0.45 9.6e-8 Economic and political preferences; TGCT cis rs9611519 0.754 rs4820435 chr22:41652846 G/T cg13695892 chr22:41940480 POLR3H -0.67 -6.44 -0.5 2.34e-9 Neuroticism; TGCT cis rs7043114 0.525 rs10116241 chr9:95240546 T/C cg14631576 chr9:95140430 CENPP -0.28 -4.52 -0.38 1.44e-5 Height; TGCT cis rs17473412 0.825 rs2115170 chr5:122663496 G/A cg15125798 chr5:122621645 NA -0.61 -5.58 -0.45 1.45e-7 Total body bone mineral density; TGCT cis rs116095464 0.558 rs28636067 chr5:199415 G/A cg22857025 chr5:266934 NA -0.35 -6.4 -0.5 2.95e-9 Breast cancer; TGCT cis rs7542091 0.704 rs4133950 chr1:210044393 C/G cg21951975 chr1:209979733 IRF6 0.6 6.1 0.48 1.24e-8 Monobrow; TGCT cis rs10851411 0.706 rs7169521 chr15:42715944 C/T cg23803468 chr15:43513504 EPB42 -0.26 -5.09 -0.42 1.29e-6 Glucose homeostasis traits; TGCT cis rs1670533 1.000 rs1670533 chr4:1078187 G/A cg27284194 chr4:1044797 NA 0.68 5.84 0.46 4.28e-8 Recombination rate (females); TGCT cis rs829418 0.582 rs747662 chr1:21947218 C/G cg04260293 chr1:22924330 EPHA8 0.43 4.6 0.38 1.03e-5 Neurocognitive impairment in HIV-1 infection (continuous); TGCT cis rs8177253 0.665 rs9831392 chr3:133451473 A/T cg01448562 chr3:133502909 NA -0.26 -5.06 -0.41 1.49e-6 Iron status biomarkers; TGCT cis rs6940116 1 rs6940116 chr6:27708732 A/G cg20933634 chr6:27740509 NA 0.44 5.07 0.41 1.38e-6 Intelligence (multi-trait analysis);Autism spectrum disorder or schizophrenia; TGCT cis rs172166 0.538 rs1150686 chr6:28161271 T/G cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.71 -0.39 6.43e-6 Cardiac Troponin-T levels; TGCT cis rs6121246 0.560 rs6088854 chr20:30225357 G/A cg18721089 chr20:30220636 NA -0.55 -5.15 -0.42 9.93e-7 Mean corpuscular hemoglobin; TGCT cis rs12142240 0.628 rs56126529 chr1:46808860 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs9436747 0.618 rs1171266 chr1:66003824 T/C cg14976592 chr1:65886160 LEPROT;LEPR -0.54 -5.02 -0.41 1.75e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs6952808 0.500 rs3800902 chr7:2144378 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -6.41 -0.5 2.79e-9 Bipolar disorder and schizophrenia; TGCT cis rs9807989 0.839 rs10182710 chr2:102981306 A/G cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs31872 0.520 rs246053 chr5:140326290 T/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Visceral adipose tissue adjusted for BMI; TGCT cis rs1862618 0.620 rs2591967 chr5:56233551 C/G cg20203395 chr5:56204925 C5orf35 0.53 4.92 0.4 2.67e-6 Initial pursuit acceleration; TGCT cis rs9308731 0.644 rs3789068 chr2:111909247 A/G cg04202892 chr2:111875749 ACOXL 0.55 6.47 0.5 2.1e-9 Chronic lymphocytic leukemia; TGCT cis rs7618915 0.547 rs2164884 chr3:52629633 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs951366 0.789 rs823152 chr1:205736285 G/A cg14159672 chr1:205819179 PM20D1 0.63 8.04 0.59 5.93e-13 Menarche (age at onset); TGCT cis rs7267979 0.549 rs11698185 chr20:25181998 T/C cg16686733 chr20:25566563 NINL 0.51 5.17 0.42 9.1e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7940866 0.804 rs3910267 chr11:130810282 C/T cg05962950 chr11:130786565 SNX19 0.67 6.68 0.51 7.1e-10 Schizophrenia; TGCT cis rs9322193 0.923 rs11155677 chr6:150078089 C/G cg13206674 chr6:150067644 NUP43 0.53 4.65 0.39 8.3e-6 Lung cancer; TGCT cis rs57920188 0.585 rs4077389 chr1:4070616 C/T cg20703997 chr1:4087676 NA 0.47 5.84 0.46 4.38e-8 Interleukin-17 levels; TGCT cis rs9486719 1.000 rs12214469 chr6:97019471 G/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT trans rs12599106 0.839 rs3853177 chr16:34498532 A/G cg03395511 chr6:291903 DUSP22 -0.65 -6.76 -0.52 4.84e-10 Menopause (age at onset); TGCT cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs1218582 0.772 rs7528532 chr1:154874440 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs28785552 0.796 rs8112908 chr19:53248041 C/T cg10871876 chr19:53194124 ZNF83 0.49 6.9 0.53 2.41e-10 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs7772486 0.817 rs9386145 chr6:146363519 A/T cg23711669 chr6:146136114 FBXO30 0.87 9.53 0.65 1.75e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6860806 0.507 rs274572 chr5:131710917 T/G cg24060327 chr5:131705240 SLC22A5 0.78 8.46 0.61 6.22e-14 Breast cancer; TGCT cis rs11148252 0.574 rs61958118 chr13:53170226 C/T cg02158880 chr13:53174818 NA 0.41 4.77 0.39 5.05e-6 Lewy body disease; TGCT cis rs1865760 0.515 rs2003208 chr6:25940719 G/C cg12310025 chr6:25882481 NA -0.53 -5.34 -0.43 4.24e-7 Height; TGCT cis rs12579753 1.000 rs2400979 chr12:82197353 T/C cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg08736216 chr1:53307985 ZYG11A -0.3 -6.08 -0.48 1.37e-8 Monocyte count; TGCT cis rs6933660 0.512 rs9383905 chr6:151804296 C/T cg03627880 chr6:151815985 C6orf97 -0.69 -6.49 -0.5 1.81e-9 Menarche (age at onset); TGCT cis rs9443645 0.901 rs56057971 chr6:79607182 G/A cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7568458 0.709 rs2028898 chr2:85777270 G/A cg17127132 chr2:85788382 GGCX 0.52 4.63 0.38 9.25e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs644799 0.710 rs10831433 chr11:95519787 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.83 9.58 0.65 1.31e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg17178900 chr1:205818956 PM20D1 0.59 7.53 0.56 9.04e-12 Menarche (age at onset); TGCT trans rs7618501 0.521 rs11709573 chr3:49956628 C/T cg21665057 chr3:196295764 WDR53;FBXO45 0.79 8.11 0.59 4.13e-13 Intelligence (multi-trait analysis); TGCT cis rs6545883 0.791 rs4672445 chr2:61655008 T/C cg15711740 chr2:61764176 XPO1 0.55 4.99 0.41 1.96e-6 Tuberculosis; TGCT cis rs5769707 0.967 rs763126 chr22:49988574 G/T cg05373962 chr22:49881684 NA 0.3 6.15 0.48 9.63e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7666738 0.687 rs6830176 chr4:99093955 G/C cg18180107 chr4:99064573 C4orf37 0.54 4.76 0.39 5.29e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs7208859 0.673 rs73263785 chr17:29214808 C/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1799949 0.896 rs33933393 chr17:41317432 C/T cg10047753 chr17:41438598 NA 0.96 9.64 0.65 9.37e-17 Menopause (age at onset); TGCT cis rs7635838 0.827 rs4273358 chr3:11415160 T/G cg00170343 chr3:11313890 ATG7 0.63 5.9 0.47 3.21e-8 HDL cholesterol; TGCT cis rs992157 0.835 rs2292550 chr2:219140288 G/C cg00012203 chr2:219082015 ARPC2 -0.78 -7.64 -0.57 5.16e-12 Colorectal cancer; TGCT cis rs295140 0.706 rs1347551 chr2:201186572 C/T cg04283868 chr2:201171347 SPATS2L 0.64 6.33 0.49 4.07e-9 QT interval; TGCT cis rs12776158 0.901 rs35355528 chr10:71216268 A/G cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg07424592 chr7:64974309 NA -1.31 -7.72 -0.57 3.33e-12 Diabetic kidney disease; TGCT cis rs597539 0.552 rs10896384 chr11:68720011 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 -0.77 -7.06 -0.54 1.05e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs3733585 0.673 rs4314284 chr4:9956096 C/T cg11266682 chr4:10021025 SLC2A9 -0.6 -8.05 -0.59 5.71e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4819052 0.851 rs2838832 chr21:46664904 A/G cg06618935 chr21:46677482 NA 0.33 5.41 0.44 3.09e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6500602 1.000 rs11647946 chr16:4462836 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.12 0.42 1.12e-6 Schizophrenia; TGCT cis rs8179 0.700 rs42044 chr7:92250140 T/G cg15732164 chr7:92237376 CDK6 -0.28 -4.8 -0.4 4.49e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT trans rs12339966 0.653 rs1489176 chr9:11276970 C/G cg07173112 chr1:1114698 TTLL10 -0.33 -6.69 -0.51 6.89e-10 Systolic blood pressure; TGCT cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg06238570 chr21:40685208 BRWD1 0.69 6.43 0.5 2.55e-9 Cognitive function; TGCT cis rs950776 0.593 rs621849 chr15:78872861 G/A cg06917634 chr15:78832804 PSMA4 -0.65 -5.32 -0.43 4.65e-7 Sudden cardiac arrest; TGCT cis rs4654899 0.758 rs4457549 chr1:21487231 A/G cg01072550 chr1:21505969 NA 0.58 9.65 0.65 9.14e-17 Superior frontal gyrus grey matter volume; TGCT cis rs911555 0.692 rs60235428 chr14:103904350 T/C cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs3806843 1.000 rs10223116 chr5:140192643 C/T cg19875535 chr5:140030758 IK 0.35 5.77 0.46 5.86e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9457247 0.871 rs1811121 chr6:167403539 T/C cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs9341808 0.718 rs10943696 chr6:80901272 C/G cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs896854 1.000 rs13255935 chr8:95965685 C/A cg16049864 chr8:95962084 TP53INP1 -0.76 -10.83 -0.7 1.24e-19 Type 2 diabetes; TGCT cis rs12497850 1.000 rs6788650 chr3:48749543 T/C cg18654377 chr3:49208889 KLHDC8B -0.44 -6.06 -0.48 1.52e-8 Parkinson's disease; TGCT cis rs72781680 0.784 rs72798406 chr2:24180144 T/C cg08917208 chr2:24149416 ATAD2B 0.77 4.77 0.39 5.02e-6 Lymphocyte counts; TGCT cis rs10504229 1.000 rs17805549 chr8:58179653 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6138458 0.626 rs6132789 chr20:25012809 C/T cg26195577 chr20:24973756 C20orf3 -0.99 -9.24 -0.64 8.46e-16 Blood protein levels; TGCT cis rs6690583 0.697 rs10782537 chr1:85484473 C/T cg22153463 chr1:85462885 MCOLN2 -0.71 -5.37 -0.43 3.75e-7 Serum sulfate level; TGCT trans rs4650994 0.525 rs2224811 chr1:178544323 C/T cg05059571 chr16:84539110 KIAA1609 0.52 10.34 0.68 1.86e-18 HDL cholesterol levels;HDL cholesterol; TGCT cis rs73198271 0.694 rs114184516 chr8:8647082 A/G cg15556689 chr8:8085844 FLJ10661 -0.6 -4.46 -0.37 1.8e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs1784581 0.894 rs1626020 chr6:162383379 G/A cg17173639 chr6:162384350 PARK2 -0.5 -9.26 -0.64 7.99e-16 Itch intensity from mosquito bite; TGCT cis rs228437 0.586 rs6935311 chr6:134911038 C/T cg09872934 chr6:134495829 SGK1 -0.51 -4.44 -0.37 1.98e-5 Melanoma; TGCT cis rs589448 0.967 rs2617834 chr12:69753365 T/C cg14784868 chr12:69753453 YEATS4 0.9 10.55 0.69 5.67e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs7091068 0.616 rs7093903 chr10:95484010 C/T cg20715218 chr10:95462985 C10orf4 -0.53 -4.93 -0.4 2.59e-6 Urinary tract infection frequency; TGCT cis rs1799949 1.000 rs67060599 chr17:41255102 A/G cg10047753 chr17:41438598 NA 0.96 9.86 0.66 2.71e-17 Menopause (age at onset); TGCT cis rs9611565 0.592 rs6519270 chr22:42078666 A/G cg13695892 chr22:41940480 POLR3H 0.85 8.19 0.59 2.72e-13 Vitiligo; TGCT cis rs13040088 1.000 rs10854167 chr20:61533039 G/C cg23096297 chr20:61557774 DIDO1 1.17 9.71 0.66 6.25e-17 Menopause (age at onset); TGCT cis rs9527 0.571 rs7096249 chr10:104618524 G/A cg15744005 chr10:104629667 AS3MT -0.5 -6.39 -0.5 3.12e-9 Arsenic metabolism; TGCT trans rs7618501 0.521 rs7615206 chr3:49937505 T/C cg21659725 chr3:3221576 CRBN 0.68 7.77 0.57 2.53e-12 Intelligence (multi-trait analysis); TGCT cis rs17184557 0.957 rs1036837 chr18:67150897 G/T cg03647455 chr18:67872746 RTTN 0.58 4.52 0.38 1.43e-5 Osteoporosis-related phenotypes; TGCT cis rs2295359 0.892 rs56920441 chr1:67652012 A/G cg08029281 chr1:67600428 NA 0.4 4.68 0.39 7.49e-6 Psoriasis; TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs10425738 0.536 rs10426903 chr19:41417719 T/C cg21111256 chr19:41386507 CYP2A7 -0.38 -4.75 -0.39 5.55e-6 nicotine metabolite ratio in current smokers;Caffeine metabolism (plasma 1,7-dimethylxanthine (paraxanthine) to 1,3,7-trimethylxanthine (caffeine) ratio); TGCT cis rs734999 0.933 rs4648648 chr1:2512452 G/A cg18854424 chr1:2615690 NA 0.46 5.85 0.47 4.1e-8 Ulcerative colitis; TGCT cis rs514406 0.644 rs7529978 chr1:53204705 G/A cg16325326 chr1:53192061 ZYG11B -0.84 -11.96 -0.73 2.15e-22 Monocyte count; TGCT cis rs6992820 0.933 rs35193637 chr8:56741274 A/C cg06880721 chr8:56792545 LYN -0.55 -4.71 -0.39 6.4e-6 Mean platelet volume; TGCT cis rs9291683 0.552 rs10939655 chr4:10014642 A/T cg02734326 chr4:10020555 SLC2A9 0.38 4.56 0.38 1.22e-5 Bone mineral density; TGCT cis rs910316 0.935 rs175076 chr14:75505486 A/G cg08847533 chr14:75593920 NEK9 -0.93 -10.19 -0.67 4.44e-18 Height; TGCT trans rs4650994 0.507 rs12405456 chr1:178512331 T/G cg05059571 chr16:84539110 KIAA1609 -0.55 -11.45 -0.72 3.74e-21 HDL cholesterol levels;HDL cholesterol; TGCT cis rs6815814 0.799 rs11466640 chr4:38778903 A/G cg02016764 chr4:38805732 TLR1 0.36 5.57 0.45 1.5e-7 Breast cancer; TGCT cis rs912057 0.833 rs1024245 chr6:6743319 A/G cg06612196 chr6:6737390 NA 0.37 4.88 0.4 3.17e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs12136530 0.593 rs881247 chr1:19733320 A/G cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs59197085 0.636 rs4728138 chr7:128468105 A/G cg00260937 chr7:128520193 KCP 0.47 4.95 0.41 2.36e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs6076065 0.707 rs1419007 chr20:23336895 T/C cg11657817 chr20:23433608 CST11 0.31 5.35 0.43 4.12e-7 Facial morphology (factor 15, philtrum width); TGCT cis rs2239547 0.618 rs4687658 chr3:52860366 C/G cg10802521 chr3:52805072 NEK4 -0.62 -5.85 -0.47 4.1e-8 Schizophrenia; TGCT cis rs7412746 0.597 rs868751 chr1:150669414 T/G cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Melanoma; TGCT cis rs10504229 0.683 rs10504221 chr8:58140256 A/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs2439831 0.867 rs689616 chr15:43761901 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs6089829 0.925 rs6122086 chr20:61664528 T/C cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs2760061 0.784 rs708116 chr1:228198196 C/A cg02753203 chr1:228287806 NA 0.31 5.94 0.47 2.62e-8 Diastolic blood pressure; TGCT cis rs3733585 0.631 rs4697924 chr4:10124239 A/G cg11266682 chr4:10021025 SLC2A9 -0.51 -5.79 -0.46 5.34e-8 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs425277 0.539 rs3107142 chr1:2044542 T/C cg03732007 chr1:2071316 PRKCZ -0.26 -5.75 -0.46 6.6e-8 Height; TGCT cis rs6570726 0.791 rs11155426 chr6:145817130 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs6951245 0.554 rs11761322 chr7:1151657 A/G cg18402987 chr7:1209562 NA 0.47 4.69 0.39 7.03e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4820539 0.966 rs5759594 chr22:23470660 G/A cg14186256 chr22:23484241 RTDR1 0.99 12.58 0.75 6.81e-24 Bone mineral density; TGCT cis rs3796352 1.000 rs11714876 chr3:53101640 C/G cg07884673 chr3:53033167 SFMBT1 -0.6 -6.23 -0.49 6.77e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs4664308 0.935 rs58354887 chr2:160927112 C/T cg03641300 chr2:160917029 PLA2R1 -0.27 -6.71 -0.52 6.31e-10 Idiopathic membranous nephropathy; TGCT trans rs459571 0.959 rs460888 chr9:136913123 C/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.77 -8.29 -0.6 1.58e-13 Platelet distribution width; TGCT cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT trans rs7618501 0.669 rs2230590 chr3:49936102 T/C cg21659725 chr3:3221576 CRBN 0.78 9.49 0.65 2.13e-16 Intelligence (multi-trait analysis); TGCT cis rs6879260 0.963 rs11738924 chr5:179727308 A/G cg23221052 chr5:179740743 GFPT2 -0.33 -5.09 -0.42 1.27e-6 Height; TGCT cis rs6570726 0.846 rs4896824 chr6:145927048 C/T cg05347473 chr6:146136440 FBXO30 0.5 4.59 0.38 1.07e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs478222 0.930 rs510107 chr2:25319471 G/A cg15423357 chr2:25149977 NA -0.46 -4.46 -0.37 1.83e-5 Type 1 diabetes; TGCT cis rs2836974 0.897 rs2836923 chr21:40524236 T/C cg06238570 chr21:40685208 BRWD1 0.71 6.39 0.5 3.04e-9 Cognitive function; TGCT cis rs17712049 0.908 rs62447155 chr7:48201162 A/G cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs12765878 0.603 rs10883944 chr10:105651657 G/T cg04788957 chr10:105438008 SH3PXD2A 0.28 4.45 0.37 1.91e-5 Coronary artery disease; TGCT cis rs2455799 0.593 rs2062823 chr3:15732256 G/T cg16303742 chr3:15540471 COLQ -0.25 -4.72 -0.39 6.27e-6 Mean platelet volume; TGCT trans rs7819412 0.660 rs7462931 chr8:10910343 G/C cg15556689 chr8:8085844 FLJ10661 -0.72 -6.88 -0.53 2.66e-10 Triglycerides; TGCT cis rs2839186 0.900 rs59828751 chr21:47708918 A/G cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs17376456 0.877 rs7728736 chr5:93404277 C/T cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs2933343 0.729 rs789224 chr3:128598231 A/C cg11901034 chr3:128598214 ACAD9 -0.64 -6.11 -0.48 1.16e-8 IgG glycosylation; TGCT cis rs9911578 0.967 rs12938821 chr17:56959422 T/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs4319547 0.508 rs10846826 chr12:122894987 C/T cg05707623 chr12:122985044 ZCCHC8 -0.63 -4.94 -0.41 2.46e-6 Body mass index; TGCT cis rs7666738 0.830 rs6853266 chr4:99047528 G/T cg18180107 chr4:99064573 C4orf37 0.58 5.24 0.43 6.75e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT trans rs877282 0.682 rs2265092 chr10:780293 C/T cg22713356 chr15:30763199 NA -0.93 -8.86 -0.62 6.95e-15 Uric acid levels; TGCT cis rs2742234 0.955 rs1800861 chr10:43613843 G/T cg02780029 chr10:43622663 RET -0.25 -4.89 -0.4 3.05e-6 Hirschsprung disease; TGCT cis rs10504229 0.728 rs17804624 chr8:58154216 T/C cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs12681287 0.752 rs10956786 chr8:87301237 T/C cg27223183 chr8:87520930 FAM82B -0.82 -5.86 -0.47 3.98e-8 Caudate activity during reward; TGCT cis rs1552244 1.000 rs55822690 chr3:10128003 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.64 -0.51 8.8e-10 Alzheimer's disease; TGCT cis rs7918232 0.882 rs10829190 chr10:27409555 C/T cg14442939 chr10:27389572 ANKRD26 0.72 5.23 0.43 6.85e-7 Breast cancer; TGCT cis rs7107174 0.901 rs11237487 chr11:78126754 G/C cg12700464 chr11:78128424 GAB2 -0.66 -4.45 -0.37 1.9e-5 Testicular germ cell tumor; TGCT cis rs28735056 0.591 rs62101204 chr18:77712832 G/A cg20368463 chr18:77673604 PQLC1 0.52 6.11 0.48 1.2e-8 Schizophrenia; TGCT cis rs644799 0.710 rs564480 chr11:95561741 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.8 8.39 0.6 9.37e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs72843506 0.722 rs9901484 chr17:20132894 G/A cg18979559 chr17:20280153 CCDC144C -0.65 -4.89 -0.4 3.07e-6 Schizophrenia; TGCT cis rs912057 0.901 rs744056 chr6:6733540 A/G cg06612196 chr6:6737390 NA 0.37 4.51 0.38 1.51e-5 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT trans rs28735056 0.563 rs12968139 chr18:77685520 A/G cg05926928 chr17:57297772 GDPD1 -0.68 -6.75 -0.52 5.1e-10 Schizophrenia; TGCT cis rs317689 0.600 rs478188 chr12:69639215 A/G cg14784868 chr12:69753453 YEATS4 0.55 4.56 0.38 1.21e-5 Response to diuretic therapy; TGCT cis rs2404602 0.647 rs12898810 chr15:76904738 T/C cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs910187 0.641 rs6124966 chr20:45813099 T/G cg27589058 chr20:45804311 EYA2 -0.33 -7.21 -0.54 4.72e-11 Migraine; TGCT cis rs7666738 0.830 rs3846445 chr4:99032939 T/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs7615952 0.799 rs13315434 chr3:125641394 T/G cg07211511 chr3:129823064 LOC729375 -0.46 -7.9 -0.58 1.26e-12 Blood pressure (smoking interaction); TGCT cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs929354 0.605 rs7806314 chr7:156946903 A/T cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs3008870 1.000 rs6673462 chr1:67461857 A/C cg08660285 chr1:67390436 MIER1;WDR78 -1.1 -11.8 -0.73 5.15e-22 Lymphocyte percentage of white cells; TGCT cis rs2010099 0.759 rs78365741 chr3:124294281 A/C cg17170942 chr3:124452405 UMPS -0.41 -4.67 -0.39 7.7e-6 Thyroid peroxidase antibody levels; TGCT cis rs9388451 0.531 rs9375414 chr6:126154475 G/A cg05901451 chr6:126070800 HEY2 -0.74 -7.69 -0.57 3.97e-12 Brugada syndrome; TGCT cis rs151997 0.924 rs32480 chr5:50208099 G/A cg06027927 chr5:50259733 NA 0.47 4.76 0.39 5.2e-6 Callous-unemotional behaviour; TGCT cis rs7246657 0.943 rs28402338 chr19:37833923 G/A cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs17221829 0.703 rs10830336 chr11:89406461 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 1.99e-5 Anxiety in major depressive disorder; TGCT cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg06481639 chr22:41940642 POLR3H -0.69 -5.97 -0.47 2.33e-8 Vitiligo; TGCT cis rs7432375 0.583 rs1609391 chr3:136615268 G/A cg12473912 chr3:136751656 NA 0.32 4.53 0.38 1.35e-5 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs2880765 0.835 rs4280192 chr15:86043020 G/A cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs853679 0.542 rs2295594 chr6:28053097 G/A cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs11190604 1.000 rs10786598 chr10:102291579 G/A cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs514406 0.584 rs7524702 chr1:53197830 G/A cg01802117 chr1:53393560 SCP2 0.42 4.92 0.4 2.64e-6 Monocyte count; TGCT trans rs1499614 1.000 rs2707832 chr7:66136549 C/T cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs7236492 0.683 rs59828426 chr18:77204397 T/C cg15644404 chr18:77186268 NFATC1 -0.35 -5.6 -0.45 1.32e-7 Inflammatory bowel disease;Crohn's disease; TGCT trans rs4332037 0.950 rs7807014 chr7:1939021 T/C cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT cis rs2243480 1.000 rs2257790 chr7:65600450 C/T cg20637647 chr7:64974828 NA 0.9 5.29 0.43 5.42e-7 Diabetic kidney disease; TGCT cis rs2820315 1.000 rs1517810 chr1:201850057 T/C cg12730843 chr1:201915899 LMOD1 -0.27 -4.79 -0.4 4.6e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg18538332 chr22:24372958 LOC391322 1.01 13.15 0.76 2.86e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7811142 1.000 rs6979335 chr7:100089860 T/C cg00814883 chr7:100076585 TSC22D4 -0.89 -9.26 -0.64 7.79e-16 Platelet count; TGCT cis rs231513 0.954 rs231493 chr17:41976998 G/C cg26893861 chr17:41843967 DUSP3 -0.71 -5.33 -0.43 4.45e-7 Cognitive function; TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs9325144 0.723 rs10161183 chr12:39182087 T/C cg26384229 chr12:38710491 ALG10B -0.61 -5.67 -0.45 9.5e-8 Morning vs. evening chronotype; TGCT cis rs6570726 0.791 rs4335004 chr6:145904764 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.85 0.66 2.95e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs556990 0.570 rs5960 chr13:113801737 C/T cg00619561 chr13:112980676 NA 0.31 4.95 0.41 2.34e-6 Blood protein levels; TGCT cis rs11718455 1.000 rs9858826 chr3:44031412 C/T cg08738300 chr3:44038990 NA -0.85 -6.49 -0.5 1.87e-9 Coronary artery disease; TGCT cis rs4689388 0.890 rs6838400 chr4:6295427 C/G cg00701064 chr4:6280414 WFS1 0.37 4.7 0.39 6.72e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2688608 0.839 rs2633311 chr10:75598099 C/T cg04320760 chr10:75533139 FUT11 0.31 4.46 0.37 1.78e-5 Inflammatory bowel disease; TGCT cis rs2354432 0.556 rs2353984 chr1:146813358 C/T cg25205988 chr1:146714368 CHD1L 1.33 6.22 0.49 7.07e-9 Mitochondrial DNA levels; TGCT trans rs4332037 0.539 rs55790766 chr7:2021248 C/T cg25206134 chr2:45395956 NA 0.97 7.33 0.55 2.6e-11 Bipolar disorder; TGCT cis rs4642101 0.561 rs6766744 chr3:12801843 C/T cg05775895 chr3:12838266 CAND2 0.5 4.85 0.4 3.69e-6 QRS complex (12-leadsum); TGCT cis rs35306767 0.903 rs11253462 chr10:889323 T/G cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs2836974 0.627 rs8127986 chr21:40687211 A/T cg17971929 chr21:40555470 PSMG1 -0.69 -5.94 -0.47 2.63e-8 Cognitive function; TGCT cis rs1670533 1.000 rs935972 chr4:1045171 A/G cg19318889 chr4:1322082 MAEA 0.22 4.61 0.38 9.86e-6 Recombination rate (females); TGCT cis rs2404602 0.622 rs2003344 chr15:76632301 T/C cg22467129 chr15:76604101 ETFA 0.49 4.88 0.4 3.23e-6 Blood metabolite levels; TGCT cis rs614226 0.744 rs787832 chr12:120986801 A/G cg01236616 chr12:121019343 POP5 1.26 13.2 0.76 2.23e-25 Type 1 diabetes nephropathy; TGCT cis rs7547997 0.654 rs10158210 chr1:158311985 A/G cg03528325 chr1:158223921 CD1A 0.33 4.81 0.4 4.38e-6 QRS duration; TGCT cis rs10207060 1.000 rs10207060 chr2:240687289 A/C cg07506560 chr2:240697449 NA 0.58 7.42 0.55 1.65e-11 Obesity-related traits; TGCT cis rs3806843 0.735 rs2530242 chr5:140053351 G/C cg19875535 chr5:140030758 IK -0.37 -6.25 -0.49 6.12e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs873946 0.648 rs12769533 chr10:134548685 C/T cg27286337 chr10:134555280 INPP5A -0.46 -5.46 -0.44 2.47e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9911578 1.000 rs4398153 chr17:56968181 T/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.21 -0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs826838 1.000 rs55828987 chr12:39056421 A/C cg26384229 chr12:38710491 ALG10B 1.01 9.58 0.65 1.31e-16 Heart rate; TGCT cis rs453301 0.686 rs11785634 chr8:8892597 G/T cg15556689 chr8:8085844 FLJ10661 -0.62 -5.24 -0.43 6.69e-7 Joint mobility (Beighton score); TGCT cis rs7267979 0.844 rs6076343 chr20:25376663 C/T cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs700590 0.723 rs304161 chr5:88134310 A/G cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.22e-7 Educational attainment (years of education); TGCT cis rs10504229 0.724 rs72649117 chr8:58037639 A/G cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs9556958 0.708 rs4772092 chr13:99166614 A/G cg15168958 chr13:99100528 FARP1 0.22 5.01 0.41 1.8e-6 Educational attainment (years of education); TGCT cis rs644799 1.000 rs617999 chr11:95589935 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.31 0.6 1.38e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6448317 1.000 rs11938296 chr4:24938861 A/G cg21108841 chr4:24914750 CCDC149 -0.65 -4.95 -0.41 2.33e-6 Heschl's gyrus morphology; TGCT cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs9985766 1.000 rs10027662 chr4:151034358 C/T cg05926478 chr4:151174724 DCLK2 -0.27 -4.81 -0.4 4.35e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs3741404 0.620 rs12787945 chr11:63977546 G/A cg00022866 chr11:64108440 CCDC88B 0.24 4.54 0.38 1.29e-5 Platelet count; TGCT cis rs11935103 0.610 rs9998003 chr4:187293933 A/G cg16785698 chr4:186456103 PDLIM3 0.44 4.62 0.38 9.55e-6 Response to citalopram treatment; TGCT cis rs2832191 1.000 rs2832184 chr21:30483265 C/T cg24692254 chr21:30365293 RNF160 -0.83 -8.72 -0.62 1.56e-14 Dental caries; TGCT cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs700651 0.786 rs58224025 chr2:198821988 G/A cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Intracranial aneurysm; TGCT cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg07507251 chr3:52567010 NT5DC2 -0.51 -7.05 -0.54 1.09e-10 Bipolar disorder; TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg09060608 chr5:178986726 RUFY1 -0.56 -6.66 -0.51 7.9e-10 Lung cancer; TGCT cis rs1475911 0.947 rs67055914 chr21:43510427 T/C cg24372256 chr21:43528868 UMODL1;C21orf128 -0.25 -4.7 -0.39 6.87e-6 IgG glycosylation; TGCT cis rs7917772 0.503 rs11191328 chr10:104305185 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.02 -0.41 1.73e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10992471 0.756 rs3758229 chr9:95078852 G/T cg14631576 chr9:95140430 CENPP -0.28 -4.55 -0.38 1.27e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs514406 0.830 rs533935 chr1:53308807 T/C cg08859206 chr1:53392774 SCP2 -0.43 -6.29 -0.49 5.07e-9 Monocyte count; TGCT trans rs57221529 0.766 rs72703070 chr5:590458 T/C cg11887960 chr12:57824829 NA 1.17 9.7 0.66 6.57e-17 Lung disease severity in cystic fibrosis; TGCT cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg12310025 chr6:25882481 NA 0.65 5.85 0.47 4.03e-8 Intelligence (multi-trait analysis); TGCT cis rs2806561 0.704 rs663942 chr1:23522476 G/A cg12483005 chr1:23474871 LUZP1 0.42 5.41 0.44 3.15e-7 Height; TGCT cis rs3008870 1.000 rs2815357 chr1:67491854 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.05 11.01 0.7 4.47e-20 Lymphocyte percentage of white cells; TGCT cis rs3771570 1.000 rs62193221 chr2:242354632 T/C cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.97e-10 Prostate cancer; TGCT cis rs8017423 0.607 rs12885664 chr14:90845697 T/C cg04374321 chr14:90722782 PSMC1 -0.51 -4.7 -0.39 6.87e-6 Mortality in heart failure; TGCT cis rs2153535 0.504 rs5001323 chr6:8451605 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.15e-8 Motion sickness; TGCT cis rs9911578 1.000 rs2611782 chr17:56717956 T/C cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs981844 1.000 rs2405430 chr4:154658391 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs73058052 0.935 rs3745473 chr19:50086626 T/C cg14048834 chr19:49990801 RPL13AP5;RPL13A -0.58 -4.55 -0.38 1.26e-5 Fibrinogen levels; TGCT cis rs59197085 0.636 rs4487676 chr7:128469362 G/A cg00260937 chr7:128520193 KCP 0.46 4.82 0.4 4.15e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs36051895 0.659 rs12348771 chr9:5083634 T/C cg02405213 chr9:5042618 JAK2 -0.78 -10.36 -0.68 1.65e-18 Pediatric autoimmune diseases; TGCT cis rs7646507 1.000 rs6445088 chr3:172495722 A/G cg10532262 chr3:172428426 NCEH1 0.97 4.9 0.4 2.89e-6 Obesity-related traits; TGCT cis rs7811142 0.887 rs35111986 chr7:100000274 C/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs7772486 0.558 rs2142978 chr6:146012061 T/C cg13319975 chr6:146136371 FBXO30 0.68 6.18 0.49 8.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7937682 0.564 rs10891277 chr11:111373103 A/G cg09085632 chr11:111637200 PPP2R1B 0.55 4.89 0.4 3.09e-6 Primary sclerosing cholangitis; TGCT cis rs6988636 1.000 rs57322232 chr8:124193532 A/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs2288278 0.502 rs62065847 chr17:46593125 C/T cg25032089 chr17:46643351 HOXB3 -0.41 -4.77 -0.39 5.17e-6 Hand grip strength; TGCT cis rs894734 0.535 rs2366144 chr12:54324069 G/T cg17708016 chr12:54321992 NA 0.61 5.4 0.44 3.32e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); TGCT cis rs2243480 0.901 rs778732 chr7:65822360 C/T cg07424592 chr7:64974309 NA 1.24 7.18 0.54 5.75e-11 Diabetic kidney disease; TGCT cis rs7937682 0.632 rs11603779 chr11:111781047 A/C cg09085632 chr11:111637200 PPP2R1B 0.84 7.34 0.55 2.4e-11 Primary sclerosing cholangitis; TGCT cis rs6089829 0.962 rs4809456 chr20:61660849 C/A cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467711 0.722 rs13201782 chr6:26651053 T/A cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.754 rs1415746 chr6:146077107 A/G cg23711669 chr6:146136114 FBXO30 -0.95 -11.1 -0.71 2.6e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.932 rs417130 chr20:25458320 T/C cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6594499 0.500 rs10491424 chr5:110453806 T/C cg04022379 chr5:110408740 TSLP 0.59 6.39 0.5 3.04e-9 Allergic disease (asthma, hay fever or eczema); TGCT cis rs6967414 0.786 rs6463578 chr7:6753050 C/A cg00387323 chr7:6746715 ZNF12 0.76 4.65 0.39 8.21e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs877529 0.625 rs714013 chr22:39533272 A/G cg18708252 chr22:39545030 CBX7 -0.38 -5.61 -0.45 1.28e-7 Multiple myeloma; TGCT cis rs2180341 0.782 rs6569490 chr6:127729615 C/T cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs7617773 0.963 rs6771787 chr3:48194242 C/T cg11946769 chr3:48343235 NME6 -0.59 -5.25 -0.43 6.49e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs9999200 chr4:99030690 A/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 1.000 rs9611565 chr22:41767486 T/C cg03806693 chr22:41940476 POLR3H -0.91 -9.45 -0.65 2.78e-16 Vitiligo; TGCT cis rs2549003 0.966 rs10072571 chr5:131816711 A/C cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs9311474 0.607 rs11711421 chr3:52561779 C/T cg10802521 chr3:52805072 NEK4 -0.73 -8.95 -0.63 4.37e-15 Electroencephalogram traits; TGCT cis rs7772486 0.790 rs3924498 chr6:146233338 A/T cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1023500 0.573 rs1807494 chr22:42474138 C/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Schizophrenia; TGCT cis rs2956278 0.717 rs2929748 chr12:84682837 A/G cg25678815 chr12:85673915 ALX1 -0.54 -4.86 -0.4 3.48e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT cis rs919433 0.713 rs6714697 chr2:198484486 C/T cg00792783 chr2:198669748 PLCL1 0.5 4.67 0.39 7.84e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs951366 0.789 rs823130 chr1:205714372 C/T cg07167872 chr1:205819463 PM20D1 0.57 7.24 0.55 4.11e-11 Menarche (age at onset); TGCT cis rs13118159 0.556 rs4974615 chr4:1373551 A/G cg19318889 chr4:1322082 MAEA -0.25 -6.29 -0.49 4.89e-9 Longevity; TGCT cis rs10197940 0.532 rs13425170 chr2:152387112 A/C cg06191203 chr2:152266755 RIF1 -0.71 -6.35 -0.5 3.72e-9 Lung cancer; TGCT cis rs9300255 0.544 rs10772995 chr12:123671761 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.69 0.46 8.5e-8 Neutrophil percentage of white cells; TGCT cis rs2439831 0.681 rs825740 chr15:43592408 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.99 7.99 0.58 7.86e-13 Lung cancer in ever smokers; TGCT cis rs7677751 0.767 rs6554158 chr4:55066077 G/A cg17187183 chr4:55093834 PDGFRA 0.48 6.45 0.5 2.26e-9 Corneal astigmatism; TGCT cis rs6951245 1.000 rs78158942 chr7:1090440 G/T cg03188948 chr7:1209495 NA 0.65 5.5 0.44 2.07e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9527 0.615 rs10883811 chr10:104727279 A/G cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs2594989 0.943 rs2454509 chr3:11489653 C/T cg26283222 chr3:11613257 VGLL4 0.21 4.46 0.37 1.84e-5 Circulating chemerin levels; TGCT cis rs6860806 0.507 rs272854 chr5:131688017 C/T cg24060327 chr5:131705240 SLC22A5 -0.75 -8.12 -0.59 3.87e-13 Breast cancer; TGCT cis rs10504229 1.000 rs7007805 chr8:58179327 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6570726 0.935 rs365658 chr6:145844588 C/T cg23711669 chr6:146136114 FBXO30 0.69 6.69 0.51 7.01e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs11809207 1.000 rs4659412 chr1:26518470 C/T cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs1799949 0.965 rs4793204 chr17:41279298 A/G cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs8177253 1.000 rs8177272 chr3:133482870 C/T cg01448562 chr3:133502909 NA -0.33 -6.62 -0.51 9.75e-10 Iron status biomarkers; TGCT cis rs6565180 0.962 rs6565183 chr16:30382755 T/C cg17640201 chr16:30407289 ZNF48 -0.9 -9.03 -0.63 2.81e-15 Tonsillectomy; TGCT cis rs9914544 1.000 rs8066385 chr17:18761133 C/T cg26306683 chr17:18585705 ZNF286B 0.57 5.08 0.41 1.36e-6 Educational attainment (years of education); TGCT cis rs7267979 1.000 rs2297497 chr20:25297909 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs155076 1.000 rs261369 chr13:21868420 C/A cg14456004 chr13:21872349 NA -1.18 -10.05 -0.67 9.55e-18 White matter hyperintensity burden; TGCT cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg12310025 chr6:25882481 NA -0.61 -5.42 -0.44 3.04e-7 Intelligence (multi-trait analysis); TGCT cis rs6831352 0.918 rs17817359 chr4:100054197 G/T cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs477895 0.653 rs11603212 chr11:63927810 C/T cg04317338 chr11:64019027 PLCB3 -0.77 -6.95 -0.53 1.81e-10 Mean platelet volume; TGCT cis rs523522 0.962 rs7488320 chr12:120981630 G/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs1385374 0.858 rs11059927 chr12:129294333 T/C cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs10197940 0.578 rs6718372 chr2:152345871 C/G cg06191203 chr2:152266755 RIF1 -0.61 -5.14 -0.42 1.03e-6 Lung cancer; TGCT cis rs2486288 0.656 rs6493145 chr15:45573862 G/T cg14582100 chr15:45693742 SPATA5L1 -0.45 -5.33 -0.43 4.53e-7 Glomerular filtration rate; TGCT cis rs35146811 0.735 rs1043915 chr7:99799845 T/A cg13334819 chr7:99746414 C7orf59 -0.71 -5.83 -0.46 4.56e-8 Coronary artery disease; TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg22166914 chr1:53195759 ZYG11B -0.36 -6.11 -0.48 1.22e-8 Monocyte count; TGCT cis rs4499344 0.693 rs382416 chr19:33107938 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.72 -7.25 -0.55 4.02e-11 Mean platelet volume; TGCT cis rs1552244 0.882 rs6443276 chr3:10008905 C/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.46 0.44 2.5e-7 Alzheimer's disease; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg06873352 chr17:61820015 STRADA -0.55 -6.07 -0.48 1.43e-8 Prudent dietary pattern; TGCT cis rs2120019 1.000 rs7168680 chr15:75369212 G/A cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT cis rs17376456 0.569 rs6879620 chr5:93119893 G/A cg21475434 chr5:93447410 FAM172A -0.6 -4.9 -0.4 2.92e-6 Diabetic retinopathy; TGCT cis rs35934224 0.783 rs13056219 chr22:19860846 C/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.06 -0.41 1.47e-6 Glaucoma (primary open-angle); TGCT cis rs12210905 0.541 rs56099947 chr6:27490937 G/T cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs4294134 0.608 rs13233394 chr7:135243240 T/C cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs9906944 0.707 rs729003 chr17:47117775 C/T cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs644148 0.967 rs2686778 chr19:44972257 G/A cg15540054 chr19:45004280 ZNF180 -0.59 -5.21 -0.42 7.8e-7 Personality dimensions; TGCT cis rs9790314 0.846 rs9815222 chr3:160994897 C/T cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs4788570 0.697 rs4788559 chr16:71848959 T/C cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.539 rs11247997 chr4:1361057 T/C cg00684032 chr4:1343700 KIAA1530 0.24 5.03 0.41 1.66e-6 Obesity-related traits; TGCT cis rs7552404 0.961 rs211710 chr1:76109038 G/A cg10523679 chr1:76189770 ACADM -0.92 -10.05 -0.67 9.78e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2204008 0.528 rs11503820 chr12:38395379 G/A cg26384229 chr12:38710491 ALG10B -0.52 -4.54 -0.38 1.32e-5 Bladder cancer; TGCT cis rs453301 0.606 rs6981060 chr8:8908235 C/A cg08975724 chr8:8085496 FLJ10661 -0.58 -4.75 -0.39 5.63e-6 Joint mobility (Beighton score); TGCT cis rs533581 0.844 rs548591 chr16:88974516 A/G cg16701003 chr16:89028210 CBFA2T3 0.34 4.76 0.39 5.2e-6 Social autistic-like traits; TGCT cis rs425277 1.000 rs385039 chr1:2077409 C/T cg03732007 chr1:2071316 PRKCZ -0.26 -5.55 -0.45 1.67e-7 Height; TGCT cis rs7666738 0.800 rs11941885 chr4:99072921 A/C cg05340658 chr4:99064831 C4orf37 0.55 6.22 0.49 7.09e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs6714710 0.603 rs17488897 chr2:98365164 G/C cg26665480 chr2:98280029 ACTR1B 0.69 6.52 0.51 1.61e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs875971 1.000 rs2042133 chr7:65931922 A/G cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.12e-6 Aortic root size; TGCT cis rs112217694 1.000 rs17249363 chr4:104657689 A/G cg24090629 chr4:104641072 TACR3 -1.01 -4.96 -0.41 2.29e-6 Menarche (age at onset); TGCT cis rs1552244 0.748 rs113890152 chr3:10085986 A/G cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs13108904 0.518 rs4974602 chr4:1342391 C/T cg13395646 chr4:1353034 KIAA1530 -0.59 -8.0 -0.58 7.57e-13 Obesity-related traits; TGCT cis rs9787249 0.957 rs12074147 chr1:40203722 T/C cg20968010 chr1:40505947 CAP1 -0.53 -4.96 -0.41 2.3e-6 Blood protein levels; TGCT cis rs732765 0.734 rs7153812 chr14:75173490 G/A cg06637938 chr14:75390232 RPS6KL1 -0.57 -4.97 -0.41 2.2e-6 Non-small cell lung cancer; TGCT cis rs860295 0.580 rs10908483 chr1:155866834 C/T cg05700447 chr1:155978627 NA 0.22 4.6 0.38 1.02e-5 Body mass index; TGCT cis rs7017914 0.934 rs7006615 chr8:71639807 T/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs4925386 0.802 rs6142735 chr20:60918087 G/C cg06026331 chr20:60912101 LAMA5 0.41 6.87 0.52 2.82e-10 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs7949030 0.626 rs35587183 chr11:62318656 C/T cg11742103 chr11:62369870 EML3;MTA2 0.55 6.35 0.5 3.69e-9 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs881375 0.678 rs1930782 chr9:123687905 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.97 0.41 2.18e-6 Rheumatoid arthritis; TGCT cis rs7267979 0.932 rs4280527 chr20:25544014 A/G cg16686733 chr20:25566563 NINL 0.55 5.46 0.44 2.46e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3125734 0.633 rs3902162 chr10:64041817 C/T cg09941381 chr10:64027924 RTKN2 -0.33 -4.92 -0.4 2.65e-6 Rheumatoid arthritis; TGCT cis rs9910055 0.529 rs2523161 chr17:42179405 C/T cg19774624 chr17:42201019 HDAC5 0.73 7.1 0.54 8.3e-11 Total body bone mineral density; TGCT cis rs587847 0.708 rs11073240 chr15:37634216 G/A cg00216138 chr15:37171175 LOC145845 0.32 4.74 0.39 5.71e-6 Intraocular pressure; TGCT cis rs597539 0.690 rs635529 chr11:68626294 C/T cg06028808 chr11:68637592 NA 0.55 6.9 0.53 2.37e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7811142 0.830 rs11765869 chr7:99964789 T/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs9443645 0.901 rs13191068 chr6:79714867 T/C cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.870 rs12499546 chr4:1255194 C/T cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.8e-6 Obesity-related traits; TGCT cis rs13256369 1.000 rs10103769 chr8:8573036 G/T cg18904891 chr8:8559673 CLDN23 0.62 5.67 0.45 9.47e-8 Obesity-related traits; TGCT cis rs79149102 0.579 rs7173218 chr15:75315328 A/G cg09165964 chr15:75287851 SCAMP5 -1.05 -5.73 -0.46 7.26e-8 Lung cancer; TGCT cis rs4819052 0.851 rs7276828 chr21:46695039 T/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7428 0.545 rs17026212 chr2:85551696 T/G cg24342717 chr2:85555507 TGOLN2 -0.48 -8.29 -0.6 1.6e-13 Ear protrusion; TGCT cis rs2842992 0.789 rs4709376 chr6:160226337 A/G cg11366901 chr6:160182831 ACAT2 1.03 6.98 0.53 1.59e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs1008375 0.966 rs10489036 chr4:17697687 A/G cg10189774 chr4:17578691 LAP3 0.57 4.86 0.4 3.41e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17764205 0.713 rs17696611 chr19:3259171 C/A cg18738857 chr19:3606974 TBXA2R -0.76 -4.6 -0.38 1.01e-5 Bipolar disorder and schizophrenia; TGCT cis rs2594989 0.887 rs9985349 chr3:11591200 T/G cg00170343 chr3:11313890 ATG7 -0.69 -5.1 -0.42 1.22e-6 Circulating chemerin levels; TGCT cis rs1865760 0.534 rs1541988 chr6:25950804 C/A cg12310025 chr6:25882481 NA -0.54 -5.6 -0.45 1.31e-7 Height; TGCT cis rs2235642 0.893 rs2143285 chr16:1593171 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.3 -4.95 -0.41 2.35e-6 Coronary artery disease; TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg27535305 chr1:53392650 SCP2 -0.28 -5.42 -0.44 2.93e-7 Monocyte count; TGCT cis rs5760092 0.755 rs5760096 chr22:24247310 A/G cg25703541 chr22:24373054 LOC391322 -0.71 -6.41 -0.5 2.72e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9926296 0.542 rs12599531 chr16:89909401 C/T cg04287289 chr16:89883240 FANCA -0.68 -6.38 -0.5 3.23e-9 Vitiligo; TGCT cis rs6951245 1.000 rs74785791 chr7:1088494 T/C cg27454412 chr7:1067447 C7orf50 0.57 4.48 0.37 1.71e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg25151919 chr3:44754333 ZNF502 -0.47 -5.58 -0.45 1.46e-7 Depressive symptoms; TGCT cis rs2997447 0.846 rs12071062 chr1:26412199 T/G cg03844060 chr1:26490628 NA 0.28 4.57 0.38 1.16e-5 QRS complex (12-leadsum); TGCT cis rs2839186 0.632 rs17176110 chr21:47706535 C/A cg12516959 chr21:47718080 NA -0.3 -4.49 -0.37 1.58e-5 Testicular germ cell tumor; TGCT cis rs2303745 0.589 rs10401700 chr19:17397700 A/C cg02221750 chr19:17393354 ANKLE1 -0.48 -6.22 -0.49 6.97e-9 Systemic lupus erythematosus; TGCT trans rs3780486 0.813 rs3780488 chr9:33133812 T/C cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs12477438 0.798 rs2084987 chr2:99587885 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs12477438 0.765 rs56167745 chr2:99600478 T/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -4.86 -0.4 3.51e-6 Chronic sinus infection; TGCT cis rs3806843 1.000 rs3756342 chr5:140165624 G/A cg19875535 chr5:140030758 IK 0.37 6.34 0.49 3.89e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs9926296 0.585 rs8045232 chr16:89857548 A/G cg26513180 chr16:89883248 FANCA 1.05 14.79 0.8 3.68e-29 Vitiligo; TGCT cis rs12134245 0.747 rs17501512 chr1:92012481 C/G cg02896835 chr1:92012615 NA 0.29 4.81 0.4 4.22e-6 Breast cancer; TGCT cis rs9611565 0.614 rs4822053 chr22:42212936 C/A cg17554472 chr22:41940697 POLR3H -0.45 -4.76 -0.39 5.32e-6 Vitiligo; TGCT cis rs950027 0.620 rs1153855 chr15:45660758 C/G cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs801193 0.569 rs6951302 chr7:66132512 T/C cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs9807841 0.670 rs2360942 chr19:10780802 G/A cg17848348 chr19:10766748 ILF3 -0.4 -4.58 -0.38 1.12e-5 Inflammatory skin disease; TGCT cis rs2046867 0.818 rs6789061 chr3:72888690 C/T cg25664220 chr3:72788482 NA -0.57 -6.33 -0.49 4.08e-9 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs8017423 0.967 rs11628812 chr14:90713720 G/T cg04374321 chr14:90722782 PSMC1 -0.77 -8.03 -0.58 6.42e-13 Mortality in heart failure; TGCT cis rs7586673 0.893 rs889925 chr2:161971597 T/C cg22496339 chr2:162101262 NA 0.53 4.81 0.4 4.27e-6 Intelligence (multi-trait analysis); TGCT cis rs17601876 0.807 rs12910259 chr15:51555049 G/A cg19946085 chr15:51559439 CYP19A1 -0.32 -4.84 -0.4 3.84e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT trans rs4942242 0.763 rs7327129 chr13:44233014 T/C cg19169023 chr15:41853346 TYRO3 -0.35 -6.7 -0.52 6.53e-10 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs9325144 0.554 rs7960616 chr12:39096664 T/A cg10518543 chr12:38710700 ALG10B -0.49 -4.58 -0.38 1.11e-5 Morning vs. evening chronotype; TGCT cis rs873946 0.586 rs12767391 chr10:134573844 A/G cg05985448 chr10:134359359 INPP5A -0.19 -4.58 -0.38 1.13e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9341808 0.527 rs7453746 chr6:80810013 T/G cg08355045 chr6:80787529 NA 0.33 5.84 0.46 4.34e-8 Sitting height ratio; TGCT cis rs6665290 0.901 rs12410103 chr1:227197408 T/C cg10327440 chr1:227177885 CDC42BPA -0.99 -20.13 -0.88 6.85e-41 Myeloid white cell count; TGCT cis rs35883536 0.647 rs2050474 chr1:101082131 G/C cg06223162 chr1:101003688 GPR88 -0.41 -7.28 -0.55 3.38e-11 Monocyte count; TGCT cis rs11690935 0.885 rs10202823 chr2:172780132 T/C cg13550731 chr2:172543902 DYNC1I2 -0.92 -8.36 -0.6 1.11e-13 Schizophrenia; TGCT cis rs57590327 0.555 rs6795133 chr3:81756267 A/G cg07356753 chr3:81810745 GBE1 -0.77 -7.2 -0.54 5.2e-11 Extraversion; TGCT cis rs6951245 0.872 rs75493422 chr7:1072890 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.82 -0.4 4.12e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7528684 0.779 rs1537949 chr1:157701249 T/C cg17134153 chr1:157670328 FCRL3 -0.26 -4.66 -0.39 8.17e-6 Insulinoma-associated antigen 2 autoantibody levels in type 1 diabetes; TGCT cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs17152411 1.000 rs7082846 chr10:126593310 C/A cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs6424115 0.679 rs2076345 chr1:24083494 C/T cg15997130 chr1:24165203 NA -0.67 -6.3 -0.49 4.75e-9 Immature fraction of reticulocytes; TGCT cis rs7731657 0.537 rs7709977 chr5:130367086 A/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs9379945 1 rs9379945 chr6:26907831 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.57 -4.71 -0.39 6.51e-6 Intelligence (multi-trait analysis); TGCT cis rs10876993 0.890 rs1092472 chr12:58036688 G/T cg15848620 chr12:58087721 OS9 -0.72 -5.78 -0.46 5.57e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs7666738 0.830 rs11097605 chr4:98985167 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs17443541 0.507 rs6726848 chr2:200451027 G/A cg00055341 chr2:200446845 NA -0.31 -4.45 -0.37 1.89e-5 Intelligence (multi-trait analysis); TGCT cis rs4273100 0.607 rs8072587 chr17:19211073 C/G cg01534423 chr17:18965556 NA -0.78 -7.04 -0.53 1.16e-10 Schizophrenia; TGCT trans rs877282 0.898 rs11253338 chr10:759559 C/T cg22713356 chr15:30763199 NA 1.0 7.29 0.55 3.23e-11 Uric acid levels; TGCT cis rs12908161 0.959 rs3748376 chr15:85328352 C/T cg17173187 chr15:85201210 NMB 0.55 6.15 0.48 9.95e-9 Schizophrenia; TGCT cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2072499 0.898 rs2736609 chr1:156202640 C/T cg24450063 chr1:156163899 SLC25A44 1.05 11.04 0.7 3.74e-20 Testicular germ cell tumor; TGCT cis rs1577917 0.958 rs10944137 chr6:86454314 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.43 -0.44 2.81e-7 Response to antipsychotic treatment; TGCT cis rs2777491 1.000 rs7168177 chr15:41715585 A/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.01 -0.7 4.47e-20 Ulcerative colitis; TGCT cis rs7666738 0.791 rs10013680 chr4:99023030 G/C cg05340658 chr4:99064831 C4orf37 0.51 5.6 0.45 1.33e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6088580 0.634 rs4911419 chr20:32995873 G/A cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs1552244 1.000 rs35993975 chr3:10067794 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.2e-8 Alzheimer's disease; TGCT cis rs911555 0.926 rs2756121 chr14:103989581 T/A cg12935359 chr14:103987150 CKB 0.38 5.35 0.43 4.18e-7 Intelligence (multi-trait analysis); TGCT cis rs9911578 0.835 rs723991 chr17:56482039 G/A cg12560992 chr17:57184187 TRIM37 -0.77 -8.97 -0.63 3.76e-15 Intelligence (multi-trait analysis); TGCT trans rs17685 0.725 rs2302436 chr7:75676988 A/T cg19862616 chr7:65841803 NCRNA00174 -0.5 -8.42 -0.6 7.75e-14 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs68170813 0.559 rs12535081 chr7:106979291 C/T cg02696742 chr7:106810147 HBP1 -0.73 -6.07 -0.48 1.42e-8 Coronary artery disease; TGCT cis rs6500602 0.727 rs11076837 chr16:4569440 C/T cg09549813 chr16:4587862 C16orf5 -0.28 -4.46 -0.37 1.78e-5 Schizophrenia; TGCT cis rs2404602 0.684 rs57682236 chr15:76868478 G/A cg22467129 chr15:76604101 ETFA 0.47 4.61 0.38 9.77e-6 Blood metabolite levels; TGCT cis rs951366 0.622 rs11580015 chr1:205676088 G/C cg07167872 chr1:205819463 PM20D1 0.57 7.29 0.55 3.14e-11 Menarche (age at onset); TGCT cis rs4919044 0.599 rs10882124 chr10:94665826 A/G cg05127821 chr10:94822908 CYP26C1 -0.76 -4.54 -0.38 1.32e-5 Coronary artery disease; TGCT cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg09323728 chr8:95962352 TP53INP1 -0.49 -6.32 -0.49 4.22e-9 Type 2 diabetes; TGCT cis rs904251 0.828 rs2797803 chr6:37487340 T/C cg08126542 chr6:37504118 NA -0.44 -5.94 -0.47 2.73e-8 Cognitive performance; TGCT cis rs77106637 0.932 rs7109082 chr11:72707441 A/C cg03713592 chr11:72463424 ARAP1 0.84 5.48 0.44 2.26e-7 Type 2 diabetes; TGCT cis rs3008870 0.755 rs2755254 chr1:67470855 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.82 8.51 0.61 4.75e-14 Lymphocyte percentage of white cells; TGCT cis rs2180341 1.000 rs13218061 chr6:127653758 G/A cg24812749 chr6:127587940 RNF146 0.98 7.64 0.57 5.06e-12 Breast cancer; TGCT cis rs1580019 0.587 rs7805311 chr7:32558302 A/G cg07520158 chr7:32535189 LSM5;AVL9 -0.57 -5.05 -0.41 1.52e-6 Cognitive ability; TGCT cis rs4642101 0.824 rs11717013 chr3:12843862 A/C cg05775895 chr3:12838266 CAND2 0.73 7.24 0.55 4.1e-11 QRS complex (12-leadsum); TGCT cis rs6121246 0.609 rs2376998 chr20:30340663 T/C cg10886678 chr20:30946050 ASXL1 -0.52 -4.44 -0.37 1.97e-5 Mean corpuscular hemoglobin; TGCT cis rs782590 0.738 rs4312532 chr2:55812061 A/G cg18811423 chr2:55921094 PNPT1 -0.62 -6.29 -0.49 4.93e-9 Metabolic syndrome; TGCT trans rs6089829 0.851 rs6089827 chr20:61668845 C/T cg13615516 chr5:77269221 NA 0.72 9.08 0.63 2.05e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs4389656 0.806 rs71600238 chr5:6763238 T/C cg12187999 chr5:6845652 NA -0.33 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs61774743 0.521 rs60144015 chr1:41845246 C/A cg01193554 chr1:41846683 NA -0.41 -5.01 -0.41 1.86e-6 Intelligence (multi-trait analysis); TGCT cis rs9910055 0.659 rs2246287 chr17:42232442 C/G cg13607699 chr17:42295918 UBTF 0.59 5.44 0.44 2.67e-7 Total body bone mineral density; TGCT cis rs1865760 1.000 rs9358893 chr6:25921761 A/G cg16482183 chr6:26056742 HIST1H1C 0.51 4.59 0.38 1.06e-5 Height; TGCT cis rs12220238 1.000 rs10824125 chr10:75997498 T/C cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.84 0.58 1.79e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs11098499 0.909 rs1546504 chr4:120241179 C/T cg09307838 chr4:120376055 NA 0.62 5.87 0.47 3.66e-8 Corneal astigmatism; TGCT cis rs6687430 0.526 rs12127400 chr1:10613660 C/T cg17425144 chr1:10567563 PEX14 0.51 5.95 0.47 2.54e-8 Hand grip strength; TGCT cis rs2742417 0.904 rs2251021 chr3:45796657 A/G cg04837898 chr3:45731254 SACM1L 0.49 4.96 0.41 2.23e-6 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs4819052 0.851 rs28442024 chr21:46674475 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.8 6.98 0.53 1.55e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs17345786 0.511 rs13061565 chr3:101392270 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.03 0.41 1.65e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.863 rs2665834 chr17:61904724 T/C cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11098499 0.754 rs878376 chr4:120237702 G/A cg09307838 chr4:120376055 NA 0.58 5.49 0.44 2.15e-7 Corneal astigmatism; TGCT cis rs778371 0.659 rs2289911 chr2:233704252 A/G cg08000102 chr2:233561755 GIGYF2 -0.67 -7.64 -0.57 5.21e-12 Schizophrenia; TGCT cis rs6840360 0.642 rs2709815 chr4:152363772 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs9517320 0.515 rs61969456 chr13:99174799 C/G cg20487152 chr13:99095054 FARP1 -0.24 -4.54 -0.38 1.29e-5 Longevity; TGCT cis rs6460942 1.000 rs112794590 chr7:12319426 G/A cg06484146 chr7:12443880 VWDE -0.54 -4.55 -0.38 1.26e-5 Coronary artery disease; TGCT cis rs9397585 0.502 rs6557273 chr6:153443159 A/G cg24028809 chr6:153414101 RGS17 0.22 4.66 0.39 8.15e-6 Body mass index; TGCT cis rs4925325 1.000 rs4925325 chr20:60514224 G/A cg16423285 chr20:60520624 NA 0.77 9.31 0.64 5.84e-16 Obesity-related traits; TGCT cis rs11098499 0.955 rs7684942 chr4:120162201 C/T cg24670566 chr4:120433619 PDE5A 0.23 4.45 0.37 1.89e-5 Corneal astigmatism; TGCT cis rs10114408 0.959 rs10821255 chr9:96656549 A/C cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 7e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9372253 0.967 rs9400379 chr6:110713783 A/G cg01119278 chr6:110721349 DDO -0.33 -5.4 -0.44 3.34e-7 Platelet distribution width; TGCT cis rs13256369 0.851 rs13258283 chr8:8563630 T/C cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs1008375 1.000 rs555 chr4:17625658 A/G cg10189774 chr4:17578691 LAP3 0.59 5.28 0.43 5.68e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg25151919 chr3:44754333 ZNF502 -0.41 -4.74 -0.39 5.87e-6 Depressive symptoms; TGCT cis rs1797081 0.967 rs811912 chr10:16859618 G/C cg23933602 chr10:16859644 RSU1 1.04 13.14 0.76 3.06e-25 Platelet distribution width; TGCT cis rs13108904 0.652 rs2878539 chr4:1243877 C/T cg03303774 chr4:1407052 NA 0.31 4.93 0.41 2.54e-6 Obesity-related traits; TGCT cis rs734999 0.505 rs10910107 chr1:2539181 C/T cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs2795502 1.000 rs1852959 chr10:43359636 T/C cg20628663 chr10:43360327 NA 0.45 6.35 0.5 3.67e-9 Blood protein levels; TGCT cis rs17345786 0.906 rs55710435 chr3:101180330 G/A cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.36 -0.6 1.09e-13 Colonoscopy-negative controls vs population controls; TGCT cis rs853679 0.517 rs4711165 chr6:28115184 T/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7364180 0.582 rs139568 chr22:42210985 C/T cg13695892 chr22:41940480 POLR3H 0.55 5.52 0.44 1.88e-7 Alzheimer's disease biomarkers; TGCT cis rs9467773 1.000 rs10484442 chr6:26555879 A/G cg09904177 chr6:26538194 HMGN4 0.68 6.77 0.52 4.62e-10 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.799 rs13047550 chr21:40515495 T/C cg11890956 chr21:40555474 PSMG1 1.04 10.14 0.67 5.79e-18 Cognitive function; TGCT cis rs6831352 0.734 rs3100630 chr4:100031715 T/A cg12011299 chr4:100065546 ADH4 0.39 5.2 0.42 8.04e-7 Alcohol dependence; TGCT cis rs10256972 0.516 rs12702081 chr7:1141528 T/C cg18765753 chr7:1198926 ZFAND2A -0.44 -5.16 -0.42 9.7e-7 Longevity;Endometriosis; TGCT cis rs9660180 0.967 rs12040325 chr1:1702436 G/A cg13866156 chr1:1669148 SLC35E2 -0.24 -5.86 -0.47 3.84e-8 Body mass index; TGCT cis rs2762353 0.808 rs1185153 chr6:25834548 A/G cg15691649 chr6:25882328 NA -0.35 -4.55 -0.38 1.25e-5 Blood metabolite levels; TGCT cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg06481639 chr22:41940642 POLR3H 0.73 6.57 0.51 1.27e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10883723 0.773 rs2296587 chr10:104245588 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.78 7.43 0.56 1.54e-11 Allergic disease (asthma, hay fever or eczema); TGCT cis rs1862618 0.641 rs170733 chr5:56249251 A/G cg24531977 chr5:56204891 C5orf35 0.69 7.25 0.55 4e-11 Initial pursuit acceleration; TGCT cis rs9611565 0.512 rs139560 chr22:42194962 A/G cg03806693 chr22:41940476 POLR3H -0.97 -9.87 -0.66 2.66e-17 Vitiligo; TGCT cis rs6141769 0.542 rs6119939 chr20:31315153 T/C cg13636640 chr20:31349939 DNMT3B -0.52 -4.54 -0.38 1.34e-5 Subjective well-being; TGCT cis rs710216 0.917 rs900834 chr1:43412343 A/G cg03128534 chr1:43423976 SLC2A1 -0.61 -4.46 -0.37 1.81e-5 Red cell distribution width; TGCT cis rs7666738 0.830 rs11731478 chr4:99001686 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs367615 0.731 rs58241713 chr5:108853664 G/A cg17395555 chr5:108820864 NA 0.3 5.59 0.45 1.38e-7 Colorectal cancer (SNP x SNP interaction); TGCT cis rs10779751 0.960 rs2076657 chr1:11318763 C/G cg08854313 chr1:11322531 MTOR 0.94 10.5 0.69 7.65e-19 Body mass index; TGCT cis rs9650657 0.513 rs4314618 chr8:10816772 A/G cg21775007 chr8:11205619 TDH -0.53 -5.03 -0.41 1.65e-6 Neuroticism; TGCT cis rs10504229 0.595 rs76447299 chr8:58117395 A/G cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs9811920 0.609 rs13317017 chr3:99665521 A/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.77 0.52 4.51e-10 Axial length; TGCT cis rs9443645 0.803 rs12195716 chr6:79535412 T/C cg09184832 chr6:79620586 NA -0.46 -4.99 -0.41 1.97e-6 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs11129876 chr3:40401636 C/T cg13683864 chr3:40499215 RPL14 1.01 10.48 0.69 8.65e-19 Renal cell carcinoma; TGCT cis rs68170813 0.559 rs11764448 chr7:106924928 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs8037137 0.731 rs78029804 chr15:91538920 C/T cg22570213 chr15:91497863 RCCD1 0.51 4.77 0.39 5.13e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs926938 0.584 rs1286558 chr1:115357587 C/T cg12756093 chr1:115239321 AMPD1 0.41 6.08 0.48 1.36e-8 Autism; TGCT cis rs9926296 0.605 rs3743859 chr16:89846050 A/G cg21285383 chr16:89894308 SPIRE2 -0.47 -7.46 -0.56 1.3e-11 Vitiligo; TGCT cis rs2404602 0.716 rs56351018 chr15:76824591 T/C cg22467129 chr15:76604101 ETFA -0.56 -6.65 -0.51 8.35e-10 Blood metabolite levels; TGCT cis rs1775715 1.000 rs1251363 chr10:32328526 G/C cg14930904 chr10:32216787 ARHGAP12 -0.5 -4.64 -0.38 8.69e-6 Bipolar disorder with mood-incongruent psychosis; TGCT trans rs8073060 0.544 rs225246 chr17:33944773 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.04 -0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9640161 0.702 rs11765692 chr7:150026567 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.68 0.39 7.4e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs17767294 0.612 rs9461425 chr6:27919688 G/A cg08851530 chr6:28072375 NA 0.78 4.84 0.4 3.79e-6 Parkinson's disease; TGCT cis rs11711311 0.955 rs7617313 chr3:113391740 T/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -6.77 -0.52 4.53e-10 IgG glycosylation; TGCT cis rs1801251 1.000 rs67013068 chr2:233608253 G/C cg25237894 chr2:233734115 C2orf82 0.32 5.88 0.47 3.5e-8 Coronary artery disease; TGCT cis rs3733631 0.843 rs10019555 chr4:104615281 G/A cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT cis rs17152411 0.843 rs7904691 chr10:126582927 G/T cg07906193 chr10:126599966 NA 0.43 5.25 0.43 6.46e-7 Height; TGCT trans rs3780486 0.846 rs10971419 chr9:33124161 T/C cg04842962 chr6:43655489 MRPS18A 1.22 16.02 0.82 5.54e-32 IgG glycosylation; TGCT cis rs1348850 0.632 rs10167783 chr2:178519041 G/A cg22681709 chr2:178499509 PDE11A -0.5 -6.08 -0.48 1.39e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2191566 0.691 rs59086054 chr19:44549096 C/A cg03039196 chr19:44506973 ZNF230 0.53 4.47 0.37 1.78e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs7924176 0.601 rs1874152 chr10:75836119 C/T cg19889307 chr10:75911429 ADK;AP3M1 -0.52 -4.92 -0.4 2.65e-6 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs2228479 0.557 rs57071566 chr16:89889327 T/G cg06558623 chr16:89946397 TCF25 0.55 4.79 0.4 4.69e-6 Skin colour saturation; TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg11494091 chr17:61959527 GH2 0.6 14.54 0.79 1.46e-28 Prudent dietary pattern; TGCT cis rs7618915 0.501 rs35526119 chr3:52749334 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs116095464 0.764 rs10069197 chr5:230822 G/C cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs73416724 0.544 rs732691 chr6:43240390 C/T cg24109273 chr6:43484729 YIPF3;POLR1C 0.86 4.7 0.39 6.75e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs3806843 0.607 rs246044 chr5:140330656 C/T cg07102913 chr5:140593443 PCDHB13 -0.46 -4.65 -0.39 8.2e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg03609598 chr5:56110824 MAP3K1 -0.56 -4.57 -0.38 1.14e-5 Initial pursuit acceleration; TGCT cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg16325326 chr1:53192061 ZYG11B -0.85 -11.92 -0.73 2.62e-22 Monocyte count; TGCT cis rs2243480 0.708 rs13242216 chr7:65898277 T/C cg20637647 chr7:64974828 NA 0.91 5.33 0.43 4.55e-7 Diabetic kidney disease; TGCT cis rs7216064 1.000 rs12452511 chr17:65832576 A/G cg12091567 chr17:66097778 LOC651250 -0.81 -5.99 -0.47 2.07e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs514406 0.929 rs11206035 chr1:53323571 T/C cg08736216 chr1:53307985 ZYG11A -0.3 -5.99 -0.47 2.09e-8 Monocyte count; TGCT cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs7917772 0.503 rs11191328 chr10:104305185 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.72 0.62 1.54e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1862618 0.525 rs832403 chr5:56265992 G/T cg18230493 chr5:56204884 C5orf35 0.76 5.67 0.45 9.71e-8 Initial pursuit acceleration; TGCT cis rs12220238 1.000 rs7909915 chr10:75960942 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.77 0.57 2.63e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs789859 1.000 rs789859 chr3:194405888 G/T cg21106136 chr3:194405973 FAM43A -0.36 -5.26 -0.43 6.12e-7 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs877282 0.898 rs11253350 chr10:765968 G/A cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs6684514 1.000 rs12117903 chr1:156311165 G/T cg16558208 chr1:156270281 VHLL 0.48 9.61 0.65 1.13e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6089829 0.962 rs3899032 chr20:61658542 G/A cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9916302 0.904 rs6503519 chr17:37706578 A/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT cis rs1023500 0.551 rs133371 chr22:42465574 G/A cg15557168 chr22:42548783 NA -0.22 -5.54 -0.45 1.76e-7 Schizophrenia; TGCT cis rs3540 0.512 rs8033595 chr15:91083353 G/A cg22089800 chr15:90895588 ZNF774 -0.76 -7.91 -0.58 1.22e-12 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT trans rs11722228 0.549 rs73212863 chr4:10104173 C/T cg26043149 chr18:55253948 FECH 1.18 11.39 0.72 5.19e-21 Gout;Urate levels;Serum uric acid levels; TGCT cis rs61612642 0.590 rs6931028 chr6:42193064 A/T cg01092361 chr6:42185687 MRPS10 0.98 7.15 0.54 6.56e-11 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs1005224 0.819 rs10147492 chr14:76155309 T/G cg04684003 chr14:76127793 TTLL5;C14orf1 -0.67 -5.96 -0.47 2.45e-8 Large artery stroke; TGCT cis rs9902453 1.000 rs8065059 chr17:28417376 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.74 -6.52 -0.51 1.63e-9 Coffee consumption (cups per day); TGCT cis rs6540559 0.546 rs7551944 chr1:210029430 G/C cg04352962 chr1:209979756 IRF6 0.69 4.71 0.39 6.51e-6 Cleft lip with or without cleft palate; TGCT trans rs9951602 0.512 rs9958497 chr18:76655296 G/C cg02800362 chr5:177631904 HNRNPAB 1.13 12.84 0.76 1.57e-24 Obesity-related traits; TGCT cis rs9814567 0.806 rs4074523 chr3:134325657 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.77 -7.21 -0.54 4.85e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9814567 0.752 rs4605591 chr3:134328361 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.71 -6.41 -0.5 2.8e-9 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs208520 0.633 rs7738469 chr6:66807446 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.98 -10.77 -0.7 1.66e-19 Exhaled nitric oxide output; TGCT cis rs7010267 0.570 rs6469804 chr8:120044829 G/A cg17171407 chr8:119960777 TNFRSF11B 0.25 4.49 0.37 1.59e-5 Total body bone mineral density (age 45-60); TGCT cis rs7666738 0.830 rs60007031 chr4:98824753 G/C cg17366294 chr4:99064904 C4orf37 0.7 7.45 0.56 1.42e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.810 rs35711405 chr3:10116939 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.47 -0.5 2.01e-9 Alzheimer's disease; TGCT cis rs2239785 0.959 rs129423 chr22:36657329 A/G cg15716373 chr22:36655542 APOL1 -0.43 -4.96 -0.41 2.28e-6 Glomerulosclerosis; TGCT cis rs2549003 0.966 rs10213701 chr5:131824064 T/A cg02551604 chr5:131831745 NA -0.86 -10.87 -0.7 9.47e-20 Asthma (sex interaction); TGCT cis rs9916302 0.904 rs650106 chr17:37451559 A/G cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs7949030 0.591 rs35880596 chr11:62369884 C/G cg13298116 chr11:62369859 EML3;MTA2 0.64 9.36 0.64 4.48e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7267979 1.000 rs397119 chr20:25440187 C/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6121246 0.529 rs6060142 chr20:30178028 A/G cg21427119 chr20:30132790 HM13 -0.39 -5.73 -0.46 7.06e-8 Mean corpuscular hemoglobin; TGCT cis rs7809950 0.530 rs34021916 chr7:106817901 A/G cg23024343 chr7:107201750 COG5 -0.37 -5.2 -0.42 8.08e-7 Coronary artery disease; TGCT cis rs17376456 0.825 rs13165400 chr5:93091427 G/A cg25358565 chr5:93447407 FAM172A 0.89 7.39 0.55 1.89e-11 Diabetic retinopathy; TGCT cis rs7119038 0.818 rs11217033 chr11:118673706 T/C cg19308663 chr11:118741387 NA 0.31 6.43 0.5 2.56e-9 Sjögren's syndrome; TGCT cis rs1371867 0.846 rs1788204 chr8:101303936 C/T cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs67311347 0.784 rs13326389 chr3:40459724 A/G cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs7301826 0.966 rs10734980 chr12:131294626 T/C cg14921827 chr12:131289118 STX2 0.15 4.5 0.37 1.52e-5 Plasma plasminogen activator levels; TGCT cis rs3752962 0.630 rs11870150 chr17:1948601 C/T cg24156229 chr17:1948635 NA -0.39 -7.52 -0.56 9.43e-12 Itch intensity from mosquito bite; TGCT cis rs1046896 0.627 rs7225515 chr17:80795783 C/T cg03160526 chr17:80928410 B3GNTL1 0.33 4.68 0.39 7.4e-6 Glycated hemoglobin levels; TGCT cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg17054783 chr10:134559939 INPP5A 0.24 4.61 0.38 9.88e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9677476 0.818 rs28678038 chr2:232063997 A/T cg07929768 chr2:232055508 NA 0.31 4.49 0.37 1.61e-5 Food antigen IgG levels; TGCT cis rs9303401 0.659 rs11495824 chr17:56918882 C/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs2842992 0.872 rs2758315 chr6:160158640 T/C cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs10858047 0.883 rs4839384 chr1:115101171 G/A cg12756093 chr1:115239321 AMPD1 0.46 4.66 0.39 8.09e-6 Autism; TGCT cis rs9902453 0.967 rs12450441 chr17:28495021 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs9467711 0.659 rs35304979 chr6:26356347 C/A cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7267979 0.932 rs4280527 chr20:25544014 A/G cg03522245 chr20:25566470 NINL 0.59 6.22 0.49 6.95e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs933688 1.000 rs12654787 chr5:90713259 C/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.06 0.59 5.53e-13 Smoking behavior; TGCT cis rs17331151 0.573 rs4687556 chr3:52890475 T/C cg07884673 chr3:53033167 SFMBT1 -0.5 -5.77 -0.46 5.86e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs826838 0.809 rs11169666 chr12:39211300 T/C cg13010199 chr12:38710504 ALG10B 0.73 5.8 0.46 5.2100000000000003e-08 Heart rate; TGCT cis rs6570726 0.791 rs6570692 chr6:145904401 T/A cg13319975 chr6:146136371 FBXO30 -0.5 -4.51 -0.38 1.48e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10986311 0.832 rs9695388 chr9:127141727 C/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.2 -5.02 -0.41 1.76e-6 Vitiligo; TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg07157834 chr1:205819609 PM20D1 0.43 6.84 0.52 3.26e-10 Menarche (age at onset); TGCT cis rs4700695 0.719 rs27586 chr5:65445873 G/A cg21114390 chr5:65439923 SFRS12 -0.84 -7.45 -0.56 1.35e-11 Facial morphology (factor 19); TGCT cis rs3806843 0.735 rs801183 chr5:140091115 C/T cg19875535 chr5:140030758 IK 0.35 5.95 0.47 2.55e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs28595532 1.000 rs28595532 chr4:119716950 A/C cg11846333 chr4:119757529 SEC24D 0.83 4.62 0.38 9.65e-6 Cannabis dependence symptom count; TGCT cis rs1862618 0.853 rs861283 chr5:56184610 C/T cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs12712073 0.837 rs11692867 chr2:100759477 G/A cg22139774 chr2:100720529 AFF3 -0.38 -5.88 -0.47 3.51e-8 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs12174623 chr6:26373086 C/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs3820928 0.874 rs10176882 chr2:227896432 A/T cg11843606 chr2:227700838 RHBDD1 -0.5 -4.7 -0.39 6.8e-6 Pulmonary function; TGCT cis rs1903068 0.853 rs17773240 chr4:55999781 T/C cg09978860 chr4:56023921 NA 0.57 6.47 0.5 2.1e-9 Endometriosis; TGCT cis rs11190604 1.000 rs7073586 chr10:102307671 A/G cg23241863 chr10:102295624 HIF1AN 0.82 5.84 0.46 4.38e-8 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9682041 0.877 rs6804688 chr3:170071191 T/G cg07589077 chr3:170072950 NA 0.29 5.15 0.42 1e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs709400 0.663 rs1022736 chr14:103998423 G/C cg12935359 chr14:103987150 CKB -0.37 -5.54 -0.45 1.73e-7 Body mass index; TGCT cis rs9985766 1.000 rs28887006 chr4:151013718 T/C cg05926478 chr4:151174724 DCLK2 -0.25 -4.91 -0.4 2.82e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs2836974 0.897 rs2836944 chr21:40593539 G/A cg11644478 chr21:40555479 PSMG1 1.0 10.6 0.69 4.32e-19 Cognitive function; TGCT cis rs1949733 0.701 rs2688222 chr4:8473735 C/A cg11789530 chr4:8429930 ACOX3 0.55 4.87 0.4 3.27e-6 Response to antineoplastic agents; TGCT cis rs10493773 0.775 rs12564080 chr1:86196586 A/C cg17807903 chr1:86174739 ZNHIT6 -0.43 -6.17 -0.48 8.98e-9 Urate levels in overweight individuals; TGCT cis rs13108904 0.535 rs1250101 chr4:1236111 G/A cg19318889 chr4:1322082 MAEA -0.2 -4.83 -0.4 4.02e-6 Obesity-related traits; TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg00080972 chr5:178986291 RUFY1 -0.53 -6.54 -0.51 1.47e-9 Lung cancer; TGCT cis rs7607369 0.782 rs639913 chr2:219365971 A/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs9303401 0.614 rs34900851 chr17:56566399 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.77 0.52 4.6e-10 Cognitive test performance; TGCT cis rs6121246 0.567 rs6060260 chr20:30192907 C/T cg13852791 chr20:30311386 BCL2L1 0.69 4.54 0.38 1.33e-5 Mean corpuscular hemoglobin; TGCT cis rs77633900 0.614 rs2930681 chr15:76995150 G/A cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Non-glioblastoma glioma;Glioma; TGCT cis rs4722166 0.630 rs2091115 chr7:22810166 G/T cg26061582 chr7:22766209 IL6 0.46 6.12 0.48 1.14e-8 Lung cancer; TGCT cis rs916888 0.531 rs183211 chr17:44788310 G/A cg15921436 chr17:44337874 NA 0.41 6.31 0.49 4.55e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2073300 1.000 rs6048803 chr20:23438889 A/G cg09953122 chr20:23471693 CST8 -0.62 -4.59 -0.38 1.08e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs9807989 0.507 rs6734762 chr2:103062926 C/T cg03938978 chr2:103052716 IL18RAP 0.27 5.34 0.43 4.19e-7 Asthma; TGCT cis rs9858542 1.000 rs1131095 chr3:49714225 T/C cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg20007245 chr22:24372913 LOC391322 -0.78 -6.29 -0.49 4.98e-9 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs6988636 1.000 rs16898086 chr8:124190445 A/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs6748734 1.000 rs11898716 chr2:241828311 A/G cg04034577 chr2:241836375 C2orf54 -0.41 -6.36 -0.5 3.5e-9 Urinary metabolites; TGCT cis rs514406 1.000 rs514406 chr1:53330458 A/G cg08736216 chr1:53307985 ZYG11A -0.31 -4.72 -0.39 6.23e-6 Monocyte count; TGCT trans rs916888 0.610 rs199529 chr17:44837217 A/C cg22433210 chr17:43662623 NA 1.01 7.37 0.55 2.14e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6964587 1.000 rs7455444 chr7:91639313 C/T cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs651907 0.557 rs35117343 chr3:101445126 A/G cg12386194 chr3:101231763 SENP7 0.48 4.63 0.38 9.23e-6 Colorectal cancer; TGCT cis rs228437 0.507 rs228440 chr6:134899380 A/G cg09872934 chr6:134495829 SGK1 0.51 4.63 0.38 9.17e-6 Melanoma; TGCT cis rs904251 0.772 rs1224127 chr6:37417556 G/A cg08126542 chr6:37504118 NA -0.4 -4.68 -0.39 7.39e-6 Cognitive performance; TGCT cis rs7618915 0.571 rs6762457 chr3:52609157 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs28595532 0.920 rs56212415 chr4:119737731 C/T cg11846333 chr4:119757529 SEC24D 0.93 4.44 0.37 2e-5 Cannabis dependence symptom count; TGCT cis rs2307449 0.964 rs758130 chr15:89873797 A/G cg24365117 chr15:89879190 POLG 0.35 4.93 0.41 2.54e-6 Menopause (age at onset); TGCT cis rs28595532 0.920 rs114916728 chr4:119776886 G/A cg14228332 chr4:119757509 SEC24D 1.26 7.08 0.54 9.26e-11 Cannabis dependence symptom count; TGCT cis rs4563143 0.514 rs73029076 chr19:29292032 G/T cg14983838 chr19:29218262 NA 0.71 5.19 0.42 8.21e-7 Methadone dose in opioid dependence; TGCT cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg09177884 chr7:1199841 ZFAND2A -0.66 -6.91 -0.53 2.3e-10 Longevity;Endometriosis; TGCT cis rs704 0.605 rs2071379 chr17:26695832 A/G cg10494684 chr17:26645200 TMEM97 -0.46 -5.09 -0.42 1.3e-6 Osteoprotegerin levels; TGCT cis rs9926296 0.605 rs12448860 chr16:89849629 T/A cg03388025 chr16:89894329 SPIRE2 0.53 9.46 0.65 2.57e-16 Vitiligo; TGCT cis rs66573146 1.000 rs6812391 chr4:6963893 G/A cg05069807 chr4:6945702 TBC1D14 0.31 4.6 0.38 1.03e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs6502955 1.000 rs6502955 chr17:6344127 C/G cg25288085 chr17:6347142 FAM64A -0.63 -5.28 -0.43 5.65e-7 Life satisfaction; TGCT cis rs4253772 0.591 rs6008365 chr22:46652929 G/A cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs1008375 0.898 rs7670500 chr4:17586957 A/G cg16339924 chr4:17578868 LAP3 0.8 6.96 0.53 1.73e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1799949 0.896 rs35908185 chr17:41255111 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.24 0.43 6.73e-7 Menopause (age at onset); TGCT cis rs9902453 0.817 rs3115089 chr17:28031881 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.76 6.84 0.52 3.17e-10 Coffee consumption (cups per day); TGCT cis rs2235642 0.893 rs8051295 chr16:1588087 A/G cg10465839 chr16:1584050 IFT140;TMEM204 -0.31 -5.09 -0.42 1.28e-6 Coronary artery disease; TGCT cis rs4563143 0.647 rs73029014 chr19:29257655 G/C cg04546413 chr19:29218101 NA 0.84 6.82 0.52 3.52e-10 Methadone dose in opioid dependence; TGCT cis rs62244186 0.545 rs7640654 chr3:44763037 A/C cg11003573 chr3:44754125 ZNF502 -0.45 -5.08 -0.42 1.32e-6 Depressive symptoms; TGCT cis rs796364 0.616 rs1523818 chr2:200684704 G/T cg17644776 chr2:200775616 C2orf69 0.31 4.59 0.38 1.07e-5 Schizophrenia; TGCT cis rs11578119 0.843 rs113019901 chr1:170543775 T/C cg09767346 chr1:170501363 GORAB 0.59 4.66 0.39 8.03e-6 Male-pattern baldness; TGCT cis rs1865760 0.625 rs9393681 chr6:26008260 A/G cg16482183 chr6:26056742 HIST1H1C 0.55 4.75 0.39 5.58e-6 Height; TGCT cis rs28595532 0.764 rs56359736 chr4:119769689 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs595982 0.527 rs35023389 chr19:49377873 G/A cg15549821 chr19:49342101 PLEKHA4 -0.66 -7.99 -0.58 7.91e-13 Red cell distribution width; TGCT trans rs1814175 0.817 rs28679516 chr11:50055998 G/A cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs12210905 0.925 rs858989 chr6:27179373 T/A cg08851530 chr6:28072375 NA -0.99 -4.79 -0.4 4.65e-6 Hip circumference adjusted for BMI; TGCT cis rs611744 0.967 rs662714 chr8:109221659 C/A cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs57221529 0.655 rs11948381 chr5:568413 A/T cg09021430 chr5:549028 NA -0.42 -5.71 -0.46 7.91e-8 Lung disease severity in cystic fibrosis; TGCT cis rs62380364 0.719 rs56947091 chr5:88160354 C/T cg22951263 chr5:87985283 NA -0.51 -5.06 -0.41 1.47e-6 Intelligence (multi-trait analysis); TGCT cis rs539096 0.872 rs2004899 chr1:44045465 A/G cg12908607 chr1:44402522 ARTN -0.49 -4.96 -0.41 2.24e-6 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.943 rs10241492 chr7:99994813 A/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs875971 0.638 rs7793569 chr7:66116633 T/G cg18876405 chr7:65276391 NA -0.34 -5.19 -0.42 8.37e-7 Aortic root size; TGCT cis rs9467711 0.606 rs34550936 chr6:26361985 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs17253792 0.822 rs80328469 chr14:56067701 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs617791 0.569 rs11227370 chr11:65747693 C/T cg09783858 chr11:65769428 EIF1AD;BANF1 0.5 4.54 0.38 1.31e-5 Breast cancer; TGCT cis rs1355223 0.583 rs2116085 chr11:34884001 C/A cg11058730 chr11:34937778 PDHX;APIP 0.8 8.94 0.63 4.53e-15 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs73001065 0.792 rs17216588 chr19:19664077 C/T cg03709012 chr19:19516395 GATAD2A 1.0 4.66 0.39 8.05e-6 LDL cholesterol; TGCT cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg11890956 chr21:40555474 PSMG1 1.03 10.96 0.7 5.74e-20 Cognitive function; TGCT cis rs864643 0.898 rs1473864 chr3:39541194 C/A cg14968361 chr3:39543547 MOBP -0.46 -4.48 -0.37 1.65e-5 Attention deficit hyperactivity disorder; TGCT cis rs10256972 0.552 rs2949195 chr7:1202705 G/A cg07092213 chr7:1199455 ZFAND2A -0.5 -5.85 -0.47 4.11e-8 Longevity;Endometriosis; TGCT cis rs2952156 0.920 rs2934956 chr17:37830447 T/A cg20243544 chr17:37824526 PNMT 0.51 4.47 0.37 1.73e-5 Asthma; TGCT cis rs9894429 1.000 rs9748176 chr17:79584043 C/G cg21028142 chr17:79581711 NPLOC4 0.29 6.74 0.52 5.33e-10 Eye color traits; TGCT cis rs1568889 1.000 rs12803655 chr11:28060785 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.86 0.62 7.07e-15 Bipolar disorder; TGCT cis rs2204008 0.580 rs11174421 chr12:38105138 A/G cg13010199 chr12:38710504 ALG10B 0.56 4.7 0.39 6.73e-6 Bladder cancer; TGCT cis rs9467773 0.534 rs34453863 chr6:26628005 T/C cg02458000 chr6:26745757 NA 0.73 7.42 0.55 1.59e-11 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.710 rs79625619 chr2:43594483 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.06 -0.41 1.47e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9467773 0.620 rs2504566 chr6:26660488 G/C cg11502198 chr6:26597334 ABT1 0.55 4.89 0.4 3.05e-6 Intelligence (multi-trait analysis); TGCT cis rs13177918 0.677 rs13177951 chr5:149825939 C/T cg14059543 chr5:149831962 NA -0.71 -9.45 -0.65 2.77e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7582180 0.629 rs34745556 chr2:100942506 A/G cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs910316 0.967 rs35446981 chr14:75637351 A/T cg11812906 chr14:75593930 NEK9 -0.73 -7.21 -0.54 4.87e-11 Height; TGCT cis rs11673344 0.562 rs7257320 chr19:37571835 C/T cg08039142 chr19:36980659 ZNF566 0.5 4.6 0.38 1.01e-5 Obesity-related traits; TGCT cis rs875971 0.862 rs6460306 chr7:66060793 T/C cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs1372520 0.684 rs10008964 chr4:90744721 G/A cg20003494 chr4:90757398 SNCA -0.63 -5.06 -0.41 1.48e-6 Neuroticism; TGCT cis rs9303401 0.625 rs34963822 chr17:56988424 C/A cg10487724 chr17:56770010 TEX14;RAD51C 0.68 6.48 0.5 1.94e-9 Cognitive test performance; TGCT cis rs9611519 0.780 rs2235849 chr22:41653540 T/G cg03806693 chr22:41940476 POLR3H -0.71 -6.7 -0.52 6.48e-10 Neuroticism; TGCT cis rs9583531 0.600 rs7984468 chr13:111362093 C/A cg24331049 chr13:111365604 ING1 0.76 7.31 0.55 2.95e-11 Coronary artery disease; TGCT cis rs13326165 0.760 rs57441156 chr3:52354242 C/G cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs9611519 0.780 rs5751071 chr22:41656332 G/A cg06634786 chr22:41940651 POLR3H -0.55 -5.04 -0.41 1.59e-6 Neuroticism; TGCT cis rs9993613 0.875 rs10938030 chr4:73454720 A/G cg15102770 chr4:73434591 ADAMTS3 -0.52 -4.7 -0.39 6.76e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs12477438 0.765 rs4374423 chr2:99662348 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs11098499 0.569 rs55845118 chr4:120290913 T/C cg09307838 chr4:120376055 NA 0.58 5.75 0.46 6.63e-8 Corneal astigmatism; TGCT cis rs10504229 1.000 rs67105789 chr8:58192002 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7959452 0.558 rs1478464 chr12:69779789 G/C cg20891283 chr12:69753455 YEATS4 0.84 8.7 0.62 1.65e-14 Blood protein levels; TGCT cis rs11648796 0.757 rs763206 chr16:770103 C/G cg07343612 chr16:622815 PIGQ -0.36 -5.13 -0.42 1.09e-6 Height; TGCT cis rs597539 0.652 rs482172 chr11:68668437 C/A cg06028808 chr11:68637592 NA 0.52 6.84 0.52 3.18e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs2153535 0.580 rs7761937 chr6:8459434 A/T cg23788917 chr6:8435910 SLC35B3 0.66 5.97 0.47 2.28e-8 Motion sickness; TGCT cis rs10833905 0.648 rs1529347 chr11:23036524 A/C cg06387204 chr11:22647648 FANCF 0.58 5.31 0.43 4.97e-7 Sudden cardiac arrest; TGCT cis rs9399135 0.967 rs6915770 chr6:135369214 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs9972944 0.756 rs7222190 chr17:63764953 T/C cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT trans rs17685 0.712 rs28456330 chr7:75810542 A/G cg19862616 chr7:65841803 NCRNA00174 0.49 8.36 0.6 1.09e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7954584 0.567 rs1720033 chr12:122384344 C/T cg22168489 chr12:122356033 WDR66 -0.22 -4.9 -0.4 2.97e-6 Mean corpuscular volume; TGCT cis rs78487399 0.808 rs998768 chr2:43711523 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.68 -0.45 9.11e-8 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7618915 0.571 rs67539070 chr3:52711974 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT trans rs1814175 0.616 rs10769644 chr11:49987676 C/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs9486719 0.741 rs2499799 chr6:96851676 T/C cg06623918 chr6:96969491 KIAA0776 0.9 6.7 0.52 6.67e-10 Migraine;Coronary artery disease; TGCT trans rs3857536 0.544 rs208453 chr6:66906841 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.74 -7.75 -0.57 2.85e-12 Blood trace element (Cu levels); TGCT cis rs877282 0.945 rs10904554 chr10:786768 T/C cg17470449 chr10:769945 NA 0.3 4.71 0.39 6.53e-6 Uric acid levels; TGCT trans rs7618501 1.000 rs7372725 chr3:49790544 C/A cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs11779988 0.545 rs427168 chr8:17784829 G/A cg01800426 chr8:17659068 MTUS1 -0.7 -5.46 -0.44 2.5e-7 Breast cancer; TGCT cis rs7819412 0.775 rs4545055 chr8:10935366 T/C cg21775007 chr8:11205619 TDH -0.5 -4.61 -0.38 9.74e-6 Triglycerides; TGCT cis rs873946 0.564 rs12263364 chr10:134555548 G/T cg18305652 chr10:134549665 INPP5A 0.31 5.07 0.41 1.42e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4713118 0.513 rs149975 chr6:27986340 G/A cg10876282 chr6:28092338 ZSCAN16 0.49 4.49 0.37 1.6e-5 Parkinson's disease; TGCT trans rs1814175 0.630 rs1722019 chr11:49904102 G/A cg03929089 chr4:120376271 NA -0.59 -6.76 -0.52 4.86e-10 Height; TGCT trans rs7615952 0.932 rs13314869 chr3:125644669 G/A cg07211511 chr3:129823064 LOC729375 -0.48 -8.02 -0.58 6.91e-13 Blood pressure (smoking interaction); TGCT cis rs9467711 0.651 rs16891264 chr6:26072445 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 0.59 4.63 0.38 9.26e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs9527 0.518 rs12776863 chr10:104641679 T/C cg15744005 chr10:104629667 AS3MT -0.62 -4.99 -0.41 1.96e-6 Arsenic metabolism; TGCT cis rs1577917 0.958 rs1591437 chr6:86525305 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.23 -0.43 7.01e-7 Response to antipsychotic treatment; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg15242686 chr22:24348715 GSTTP1 0.44 5.95 0.47 2.53e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4849845 0.637 rs4077564 chr2:121004241 C/T cg24070213 chr2:121070622 NA 0.34 4.52 0.38 1.41e-5 Mean platelet volume; TGCT cis rs916888 0.610 rs199436 chr17:44789285 C/T cg01570182 chr17:44337453 NA -0.77 -7.7 -0.57 3.69e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7246657 0.653 rs28701616 chr19:37681098 G/A cg24025825 chr19:37761650 NA -0.32 -5.08 -0.42 1.35e-6 Coronary artery calcification; TGCT cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg03264133 chr6:25882463 NA -0.68 -7.52 -0.56 9.75e-12 Blood metabolite levels; TGCT cis rs3020333 0.875 rs3020336 chr6:152013760 G/T cg22157087 chr6:152012887 ESR1 0.19 4.51 0.38 1.5e-5 Total body bone mineral density; TGCT cis rs11030122 0.661 rs4910877 chr11:4062153 A/G cg18678763 chr11:4115507 RRM1 -0.46 -5.62 -0.45 1.22e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs7575217 0.740 rs12468712 chr2:101746066 A/T cg12737833 chr2:101500543 NPAS2 0.28 4.58 0.38 1.09e-5 Sum neutrophil eosinophil counts;Myeloid white cell count;Granulocyte count; TGCT cis rs78487399 0.808 rs76851696 chr2:43746062 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9911578 0.867 rs72628394 chr17:57121313 C/T cg12560992 chr17:57184187 TRIM37 -0.79 -9.86 -0.66 2.77e-17 Intelligence (multi-trait analysis); TGCT cis rs644799 0.965 rs687529 chr11:95545587 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9467773 1.000 rs10214634 chr6:26564582 T/A cg15659132 chr6:26577336 NA 0.9 13.19 0.76 2.26e-25 Intelligence (multi-trait analysis); TGCT cis rs2738048 0.545 rs2738046 chr8:6823542 C/A cg24860332 chr8:6827800 DEFA10P -0.42 -6.08 -0.48 1.36e-8 IgA nephropathy; TGCT cis rs6951245 1.000 rs11764748 chr7:1094508 T/C cg03188948 chr7:1209495 NA 0.66 5.67 0.45 9.65e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg23131131 chr22:24373011 LOC391322 -0.84 -9.26 -0.64 7.95e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs344364 0.511 rs2917519 chr16:1950479 C/A cg26617929 chr16:1858877 NA -0.27 -4.75 -0.39 5.6e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs10256972 0.681 rs6979076 chr7:1116247 C/T cg04025307 chr7:1156635 C7orf50 -0.21 -4.73 -0.39 5.95e-6 Longevity;Endometriosis; TGCT cis rs12220238 0.908 rs10824124 chr10:75997360 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.92 7.84 0.58 1.79e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs6540559 0.546 rs75308488 chr1:210030639 T/C cg04352962 chr1:209979756 IRF6 0.68 4.63 0.38 8.97e-6 Cleft lip with or without cleft palate; TGCT cis rs10851411 0.733 rs2899051 chr15:42786160 T/C cg23803468 chr15:43513504 EPB42 0.27 5.09 0.42 1.27e-6 Glucose homeostasis traits; TGCT cis rs28386778 0.897 rs2597634 chr17:61878144 G/A cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs7917772 0.619 rs2801050 chr10:104509393 T/A cg05855489 chr10:104503620 C10orf26 -0.66 -5.19 -0.42 8.45e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7647973 0.580 rs12629759 chr3:49237394 T/C cg16497277 chr3:49208875 KLHDC8B -0.53 -5.13 -0.42 1.08e-6 Menarche (age at onset); TGCT cis rs12541335 0.639 rs13257108 chr8:22165043 T/C cg07298985 chr8:22133076 PIWIL2 0.33 5.28 0.43 5.7e-7 Hypertriglyceridemia; TGCT cis rs739496 0.579 rs73426362 chr12:112380470 G/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7666738 0.830 rs34273190 chr4:99004568 C/T cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs860295 0.580 rs867550 chr1:155880391 T/C cg13795986 chr1:155880507 RIT1 0.38 4.61 0.38 9.9e-6 Body mass index; TGCT cis rs7267979 1.000 rs6083844 chr20:25386832 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs28386778 0.897 rs7207005 chr17:61860355 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs7829975 0.871 rs572307 chr8:8578811 T/C cg06636001 chr8:8085503 FLJ10661 -0.6 -5.01 -0.41 1.84e-6 Mood instability; TGCT cis rs854765 0.927 rs4925138 chr17:17992793 T/G cg09796270 chr17:17721594 SREBF1 -0.26 -5.08 -0.42 1.35e-6 Total body bone mineral density; TGCT cis rs35771425 0.518 rs1055565 chr1:211605697 G/A cg25617285 chr1:211431773 RCOR3 -0.5 -6.09 -0.48 1.29e-8 Educational attainment (years of education); TGCT cis rs853679 0.517 rs9368555 chr6:28108967 T/C cg12963246 chr6:28129442 ZNF389 0.53 5.09 0.42 1.27e-6 Depression; TGCT cis rs35146811 0.883 rs4134903 chr7:99711040 G/A cg13334819 chr7:99746414 C7orf59 -0.81 -6.92 -0.53 2.13e-10 Coronary artery disease; TGCT cis rs924712 0.522 rs7750012 chr6:54702643 C/T cg04690482 chr6:54711388 FAM83B 0.32 4.48 0.37 1.64e-5 Breast cancer; TGCT cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -6.95 -0.53 1.82e-10 Prostate cancer; TGCT cis rs1008375 0.932 rs11935124 chr4:17668200 G/A cg16339924 chr4:17578868 LAP3 -0.58 -4.81 -0.4 4.28e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs875971 0.830 rs6950137 chr7:65976610 G/A cg11764359 chr7:65958608 NA 0.58 5.34 0.43 4.22e-7 Aortic root size; TGCT cis rs1075232 1.000 rs67634762 chr15:31748055 G/T cg01030201 chr15:31746330 NA -1.03 -5.45 -0.44 2.6e-7 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs6089584 0.526 rs6061965 chr20:60607858 A/C cg06108461 chr20:60628389 TAF4 -0.39 -4.98 -0.41 2.05e-6 Body mass index; TGCT cis rs59574136 1 rs59574136 chr7:2036460 T/C cg04267008 chr7:1944627 MAD1L1 -0.4 -5.33 -0.43 4.39e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs79349575 0.783 rs832410 chr17:46972865 C/T cg07967210 chr17:47022446 SNF8 0.44 5.9 0.47 3.17e-8 Type 2 diabetes; TGCT cis rs7507204 0.530 rs4807470 chr19:3443470 A/T cg08380311 chr19:3435252 NFIC 1.18 16.39 0.83 7.76e-33 Height; TGCT cis rs9303401 0.538 rs12603174 chr17:56489279 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.75 6.73 0.52 5.58e-10 Cognitive test performance; TGCT cis rs12765878 0.565 rs11191818 chr10:105591779 A/C cg07956775 chr10:105212289 CALHM2 -0.3 -4.52 -0.38 1.42e-5 Coronary artery disease; TGCT cis rs6558530 0.653 rs7001282 chr8:1700188 A/C cg09410841 chr8:1729607 CLN8 0.72 6.48 0.5 1.98e-9 Systolic blood pressure; TGCT cis rs10490913 1.000 rs1473141 chr10:120143158 A/G cg23160142 chr10:120154512 NA -0.3 -4.45 -0.37 1.92e-5 Cancer; TGCT cis rs769267 0.930 rs4808957 chr19:19567248 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.73 0.46 7.3e-8 Tonsillectomy; TGCT cis rs9921338 0.961 rs11545336 chr16:11439496 G/A cg00044050 chr16:11439710 C16orf75 -0.82 -6.15 -0.48 9.71e-9 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4689388 0.926 rs5018647 chr4:6292799 A/C cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs769267 0.965 rs10419245 chr19:19383755 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.34 0.49 3.86e-9 Tonsillectomy; TGCT cis rs9814567 1.000 rs1498718 chr3:134205920 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.93 -9.27 -0.64 7.51e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs617219 0.698 rs12189248 chr5:78517143 A/G cg23514016 chr5:78407564 BHMT -0.36 -5.52 -0.44 1.85e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6725041 0.819 rs10196229 chr2:213081987 C/T cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs9303401 0.659 rs61291849 chr17:56909867 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT trans rs9329221 0.711 rs55864141 chr8:9807022 T/C cg15556689 chr8:8085844 FLJ10661 -0.81 -7.5 -0.56 1.07e-11 Neuroticism; TGCT cis rs12477438 0.798 rs13414153 chr2:99624748 G/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.56 -4.86 -0.4 3.51e-6 Chronic sinus infection; TGCT cis rs4820539 0.966 rs2267001 chr22:23456696 T/C cg21100191 chr22:23484243 RTDR1 0.95 11.35 0.71 6.7e-21 Bone mineral density; TGCT cis rs9611565 0.512 rs5758465 chr22:42175314 T/C cg17554472 chr22:41940697 POLR3H 0.46 4.8 0.4 4.46e-6 Vitiligo; TGCT cis rs2120019 0.935 rs12591119 chr15:75355944 A/G cg11632617 chr15:75315747 PPCDC -0.33 -4.59 -0.38 1.07e-5 Blood trace element (Zn levels); TGCT cis rs2469997 0.925 rs2470001 chr8:120356402 C/T cg00681363 chr8:120844660 TAF2 0.74 4.87 0.4 3.3e-6 Hypertension (SNP x SNP interaction); TGCT cis rs6582630 0.555 rs2197308 chr12:38281261 A/G cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9296092 0.500 rs35150558 chr6:33519612 T/A cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs11671005 0.695 rs11673069 chr19:58934918 C/G cg13877915 chr19:58951672 ZNF132 0.65 5.14 0.42 1.04e-6 Mean platelet volume; TGCT cis rs6088580 0.601 rs6059872 chr20:33082775 C/A cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.604 rs10022185 chr4:120571765 C/G cg09307838 chr4:120376055 NA 0.65 6.3 0.49 4.68e-9 Corneal astigmatism; TGCT cis rs793571 0.502 rs387812 chr15:59074786 T/C cg05156742 chr15:59063176 FAM63B 0.56 5.26 0.43 6.22e-7 Schizophrenia; TGCT cis rs7659604 0.502 rs4516738 chr4:122669177 T/C cg19748678 chr4:122722346 EXOSC9 -0.48 -4.76 -0.39 5.32e-6 Type 2 diabetes; TGCT cis rs9393692 0.875 rs9393690 chr6:26271713 A/T cg05868516 chr6:26286170 HIST1H4H 0.63 5.94 0.47 2.72e-8 Educational attainment; TGCT cis rs7178424 0.742 rs12915825 chr15:62175636 A/G cg00456672 chr15:62358751 C2CD4A -0.31 -4.73 -0.39 6e-6 Height; TGCT cis rs2806561 0.578 rs6702719 chr1:23302576 T/C cg12483005 chr1:23474871 LUZP1 0.39 4.99 0.41 2.03e-6 Height; TGCT cis rs10769945 0.500 rs217203 chr11:1972456 G/C cg06679296 chr11:1949032 TNNT3 -0.25 -4.57 -0.38 1.16e-5 DNA methylation (variation); TGCT cis rs2204008 0.744 rs11495519 chr12:38060546 C/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg10150615 chr22:24372951 LOC391322 -0.98 -12.41 -0.74 1.75e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7917772 0.503 rs7100753 chr10:104300979 C/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs629535 0.590 rs56200825 chr8:70123450 G/A cg21567404 chr3:27674614 NA -0.54 -8.15 -0.59 3.45e-13 Dupuytren's disease; TGCT cis rs6450176 1.000 rs59061738 chr5:53296557 A/G ch.5.1024479R chr5:53302184 ARL15 -0.53 -5.12 -0.42 1.15e-6 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs67311347 0.955 rs2085114 chr3:40497437 T/A cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs4478858 0.735 rs11576621 chr1:31795460 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.94 -0.41 2.47e-6 Alcohol dependence; TGCT cis rs7552404 0.924 rs67757078 chr1:76169456 G/A cg03433033 chr1:76189801 ACADM 0.82 9.89 0.66 2.31e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6088590 1.000 rs6088615 chr20:33400474 C/T cg06115741 chr20:33292138 TP53INP2 -0.62 -5.25 -0.43 6.27e-7 Coronary artery disease; TGCT cis rs6570726 0.935 rs110289 chr6:145865176 C/G cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs151997 0.537 rs11746939 chr5:50268856 G/A cg06027927 chr5:50259733 NA 0.54 5.44 0.44 2.76e-7 Callous-unemotional behaviour; TGCT cis rs7666738 0.546 rs7679681 chr4:98882221 A/G cg17366294 chr4:99064904 C4orf37 0.67 5.94 0.47 2.64e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7659604 0.540 rs28672860 chr4:122705051 G/A cg06713675 chr4:122721982 EXOSC9 0.39 4.73 0.39 5.99e-6 Type 2 diabetes; TGCT cis rs2657888 0.542 rs7131699 chr12:56933162 T/C cg23002907 chr12:56915593 RBMS2 0.43 6.31 0.49 4.47e-9 Adiponectin levels; TGCT cis rs9902453 0.904 rs8078638 chr17:28290358 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.51 0.56 9.93e-12 Coffee consumption (cups per day); TGCT cis rs8072100 0.840 rs9900360 chr17:45491979 C/T cg08085267 chr17:45401833 C17orf57 -0.51 -5.71 -0.46 8.04e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT trans rs1814175 0.715 rs7479622 chr11:49673340 T/G cg03929089 chr4:120376271 NA -0.63 -7.05 -0.53 1.1e-10 Height; TGCT cis rs875971 1.000 rs6957199 chr7:65978519 T/C cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs1372520 0.684 rs184810 chr4:90697979 T/C cg01966878 chr4:90757139 SNCA 0.3 4.82 0.4 4.11e-6 Neuroticism; TGCT cis rs8180040 0.620 rs9844122 chr3:47108330 C/T cg27129171 chr3:47204927 SETD2 0.71 8.55 0.61 3.9e-14 Colorectal cancer; TGCT cis rs137699 1.000 rs137703 chr22:39750241 A/G cg24399712 chr22:39784796 NA -0.66 -5.73 -0.46 7.3e-8 IgG glycosylation; TGCT cis rs11577318 0.853 rs4526602 chr1:26648034 C/T cg04990556 chr1:26633338 UBXN11 -0.6 -4.96 -0.41 2.28e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs826838 0.678 rs11182781 chr12:38610178 C/T cg13010199 chr12:38710504 ALG10B 0.66 5.18 0.42 8.76e-7 Heart rate; TGCT cis rs10883723 0.810 rs7079810 chr10:104243883 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2658782 0.738 rs2605628 chr11:93261560 C/A cg15737290 chr11:93063684 CCDC67 0.7 5.24 0.43 6.55e-7 Pulmonary function decline; TGCT cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.15 0.54 6.65e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs360798 0.532 rs2421816 chr2:63075033 C/A cg17519650 chr2:63277830 OTX1 0.64 5.56 0.45 1.55e-7 Coronary artery disease; TGCT cis rs798554 0.679 rs1639036 chr7:2885089 G/A cg13628971 chr7:2884303 GNA12 0.54 4.53 0.38 1.36e-5 Height; TGCT cis rs28595532 0.920 rs115683389 chr4:119735557 T/G cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs9372253 1.000 rs9374170 chr6:110712991 A/G cg01119278 chr6:110721349 DDO -0.34 -5.45 -0.44 2.55e-7 Platelet distribution width; TGCT trans rs9951602 0.512 rs58352488 chr18:76651113 T/A cg02800362 chr5:177631904 HNRNPAB 1.15 13.03 0.76 5.64e-25 Obesity-related traits; TGCT cis rs10489202 0.632 rs203779 chr1:167877647 T/G cg24449463 chr1:168025552 DCAF6 -0.58 -6.88 -0.53 2.57e-10 Schizophrenia; TGCT cis rs10031466 0.967 rs12647135 chr4:189011174 A/C cg05865660 chr4:189158066 NA 0.21 4.48 0.37 1.68e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs12681287 0.888 rs2976201 chr8:87335937 T/C cg27223183 chr8:87520930 FAM82B -0.84 -6.5 -0.5 1.79e-9 Caudate activity during reward; TGCT cis rs4494114 1.000 rs6675245 chr1:39356820 T/A cg25970120 chr1:39325951 RRAGC -0.6 -6.17 -0.48 8.89e-9 Blood protein levels; TGCT cis rs36051895 0.623 rs7025005 chr9:5261794 T/C cg02405213 chr9:5042618 JAK2 -0.7 -9.15 -0.63 1.44e-15 Pediatric autoimmune diseases; TGCT cis rs6671200 0.607 rs2296308 chr1:95709939 G/T cg03123541 chr1:95699097 RWDD3 0.64 6.03 0.48 1.71e-8 Stearic acid (18:0) levels; TGCT cis rs6684514 1.000 rs2270291 chr1:156244992 G/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs854765 0.583 rs11869536 chr17:17826528 T/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.69 0.57 3.91e-12 Total body bone mineral density; TGCT cis rs10464366 1.000 rs10464366 chr7:39121500 A/T cg18850127 chr7:39170497 POU6F2 -0.23 -5.0 -0.41 1.9e-6 IgG glycosylation; TGCT cis rs4819052 0.885 rs9980676 chr21:46665430 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 4.99 0.41 1.98e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6740322 1.000 rs6740322 chr2:43561929 A/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -5.37 -0.43 3.66e-7 Coronary artery disease; TGCT cis rs7104764 0.957 rs7116130 chr11:244129 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs2549003 1.000 rs9282762 chr5:131822055 T/C cg00255919 chr5:131827918 IRF1 0.2 4.65 0.39 8.22e-6 Asthma (sex interaction); TGCT cis rs11997175 0.846 rs7388664 chr8:33768773 T/G ch.8.33884649F chr8:33765107 NA 0.32 4.75 0.39 5.51e-6 Body mass index; TGCT cis rs9527 0.662 rs4919686 chr10:104592249 A/C cg04362960 chr10:104952993 NT5C2 0.63 5.31 0.43 4.84e-7 Arsenic metabolism; TGCT cis rs11098499 0.775 rs67281037 chr4:120281157 G/C cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs854765 0.547 rs2955353 chr17:17948979 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs2594989 0.943 rs2442769 chr3:11491086 A/G cg00170343 chr3:11313890 ATG7 -0.66 -4.48 -0.37 1.67e-5 Circulating chemerin levels; TGCT cis rs7805747 1.000 rs7805747 chr7:151407801 G/A cg17611936 chr7:151411526 PRKAG2 0.52 6.64 0.51 8.61e-10 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.962 rs4699596 chr4:99012924 C/T cg17366294 chr4:99064904 C4orf37 0.74 6.87 0.53 2.76e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs59197085 0.636 rs4731517 chr7:128458649 A/C cg00260937 chr7:128520193 KCP -0.47 -4.98 -0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs2797780 1.000 rs2797779 chr6:37508585 C/T cg00985040 chr6:37553208 NA 0.24 4.72 0.39 6.35e-6 Systemic lupus erythematosus; TGCT cis rs877282 0.891 rs11595385 chr10:800539 A/G cg17470449 chr10:769945 NA 0.31 4.64 0.38 8.88e-6 Uric acid levels; TGCT cis rs4665809 0.590 rs2891496 chr2:26452605 G/A cg26119090 chr2:26468346 HADHA;HADHB 1.03 7.66 0.57 4.67e-12 Gut microbiome composition (summer); TGCT cis rs1218582 0.628 rs12130132 chr1:154880386 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.65 -6.77 -0.52 4.52e-10 Prostate cancer; TGCT cis rs597480 0.892 rs556669 chr11:85436394 T/C cg11817631 chr11:85522609 SYTL2 -0.47 -4.66 -0.39 8.18e-6 Drug-induced liver injury (nonsteroidal anti-inflammatory drugs); TGCT cis rs1670533 1.000 rs7673898 chr4:1056569 C/A cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs921968 0.541 rs562510 chr2:219443001 A/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7666738 0.830 rs7662114 chr4:99019985 A/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6770219 0.516 rs7646885 chr3:186134686 T/C cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.45 0.37 1.89e-5 Cerebrospinal T-tau levels; TGCT cis rs8062405 0.573 rs11645306 chr16:28983936 G/C cg01117621 chr16:28073818 GSG1L -0.37 -4.69 -0.39 7.05e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs13217239 0.646 rs10946898 chr6:27003884 T/C cg05738196 chr6:26577821 NA 0.49 4.75 0.39 5.45e-6 Schizophrenia; TGCT cis rs595982 0.517 rs10404905 chr19:49406175 A/T cg21252483 chr19:49399788 TULP2 0.31 5.33 0.43 4.55e-7 Red cell distribution width; TGCT cis rs137699 0.958 rs137705 chr22:39751394 T/C cg24399712 chr22:39784796 NA -0.63 -5.44 -0.44 2.76e-7 IgG glycosylation; TGCT cis rs9296092 0.538 rs62405953 chr6:33524760 C/T cg13560919 chr6:33536144 NA -0.22 -4.93 -0.41 2.54e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs1218582 0.741 rs6656494 chr1:154839799 A/G cg16680214 chr1:154839983 KCNN3 -0.36 -7.67 -0.57 4.44e-12 Prostate cancer; TGCT cis rs11785400 1.000 rs3735999 chr8:143746069 T/C cg10596483 chr8:143751796 JRK 0.55 5.82 0.46 4.69e-8 Schizophrenia; TGCT trans rs6089829 0.962 rs6062777 chr20:61663748 G/A cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs924607 0.898 rs905193 chr5:635095 T/C cg18765565 chr5:669397 TPPP 0.58 6.07 0.48 1.45e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7681440 0.904 rs28403500 chr4:90769729 T/G cg20003494 chr4:90757398 SNCA -0.6 -5.76 -0.46 6.3e-8 Dementia with Lewy bodies; TGCT cis rs11190604 0.945 rs2495746 chr10:102328270 T/C cg16342193 chr10:102329863 NA -0.42 -5.39 -0.44 3.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs3784262 0.669 rs7178598 chr15:58309016 C/A cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.27 -0.49 5.49e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs7618501 0.633 rs9814664 chr3:50078541 C/T cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs7715806 0.500 rs72633985 chr5:75006384 A/G cg19683494 chr5:74908142 NA 0.57 5.02 0.41 1.76e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs2012796 1.000 rs11621378 chr14:81814426 T/A cg02996355 chr14:81879375 NA 0.51 4.81 0.4 4.35e-6 Night sleep phenotypes; TGCT cis rs112217694 1.000 rs17196104 chr4:104657246 G/T cg24090629 chr4:104641072 TACR3 -1.01 -4.96 -0.41 2.29e-6 Menarche (age at onset); TGCT cis rs6987853 0.933 rs2974353 chr8:42409165 A/C cg20539142 chr8:42623718 CHRNA6 -0.19 -4.63 -0.38 9.21e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs858239 0.712 rs199650 chr7:23367189 C/T cg05602783 chr7:23145260 KLHL7 0.53 4.48 0.37 1.7e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs2439831 0.867 rs933941 chr15:43632226 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs2066819 1.000 rs17118409 chr12:56630764 G/A cg26714650 chr12:56694279 CS -1.42 -5.7 -0.46 8.43e-8 Psoriasis vulgaris; TGCT cis rs4950928 0.823 rs4950882 chr1:203164848 A/G cg17014757 chr1:203156097 CHI3L1 -0.38 -4.68 -0.39 7.54e-6 YKL-40 levels; TGCT cis rs6582630 0.555 rs35284307 chr12:38509999 T/G cg13010199 chr12:38710504 ALG10B 0.6 4.88 0.4 3.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs13191362 0.935 rs73008456 chr6:163013697 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs34526934 0.608 rs7591820 chr2:177028144 G/T cg14324370 chr2:177042789 NA -0.9 -8.57 -0.61 3.41e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs9910055 0.571 rs10208 chr17:42300278 C/T cg19774624 chr17:42201019 HDAC5 -0.65 -6.44 -0.5 2.36e-9 Total body bone mineral density; TGCT cis rs806215 0.526 rs2058457 chr7:127493657 A/T cg11539674 chr7:127291444 SND1 -0.36 -4.65 -0.39 8.46e-6 Type 2 diabetes; TGCT cis rs6912958 0.781 rs985764 chr6:88215206 G/A cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs7429990 0.932 rs6766641 chr3:48145224 G/A cg11946769 chr3:48343235 NME6 -0.56 -4.52 -0.38 1.42e-5 Educational attainment (years of education); TGCT cis rs6088590 1.000 rs2295353 chr20:33356511 C/T cg24642439 chr20:33292090 TP53INP2 0.7 6.22 0.49 7.12e-9 Coronary artery disease; TGCT cis rs2980439 0.525 rs2980508 chr8:8171732 C/T cg15556689 chr8:8085844 FLJ10661 0.62 5.52 0.44 1.89e-7 Neuroticism; TGCT cis rs739401 0.588 rs10219272 chr11:3020789 G/A cg05729581 chr11:3078854 CARS -0.53 -4.92 -0.4 2.69e-6 Longevity; TGCT cis rs11614913 0.509 rs12300425 chr12:54395082 G/T cg27482031 chr12:54402697 HOXC8 -0.57 -5.15 -0.42 9.83e-7 Waist circumference adjusted for body mass index; TGCT cis rs17376456 0.877 rs12374488 chr5:93481407 A/G cg25358565 chr5:93447407 FAM172A 0.97 8.32 0.6 1.34e-13 Diabetic retinopathy; TGCT cis rs9733 0.596 rs7538493 chr1:150655421 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs4822044 0.617 rs13054514 chr22:42130383 A/G cg13695892 chr22:41940480 POLR3H 0.84 7.96 0.58 9.2e-13 Cannabis dependence symptom count; TGCT cis rs7582180 0.629 rs6731549 chr2:100939937 T/G cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs2228479 0.702 rs3819574 chr16:89826630 G/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs3785574 0.962 rs9944483 chr17:61783553 G/T cg11494091 chr17:61959527 GH2 -0.39 -6.61 -0.51 1.01e-9 Height; TGCT cis rs3096299 0.685 rs3803682 chr16:89544636 C/T cg02187348 chr16:89574699 SPG7 0.61 6.56 0.51 1.32e-9 Multiple myeloma (IgH translocation); TGCT cis rs9467711 1.000 rs6903015 chr6:26322526 A/G cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs12780845 0.522 rs10795457 chr10:17230150 A/G cg01003015 chr10:17271136 VIM -0.49 -4.46 -0.37 1.8e-5 Homocysteine levels; TGCT cis rs11711311 0.955 rs67550112 chr3:113401988 C/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.81 -7.28 -0.55 3.35e-11 IgG glycosylation; TGCT cis rs11118844 0.739 rs10863653 chr1:221943926 T/C cg04222084 chr1:221915650 DUSP10 -0.78 -5.41 -0.44 3.1e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs7937682 0.961 rs7106104 chr11:111635655 T/C cg09085632 chr11:111637200 PPP2R1B 1.16 11.46 0.72 3.59e-21 Primary sclerosing cholangitis; TGCT cis rs4727027 0.901 rs4727017 chr7:148822062 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs12931792 0.846 rs9924308 chr16:30154740 C/T cg17640201 chr16:30407289 ZNF48 -0.61 -5.59 -0.45 1.38e-7 Tonsillectomy; TGCT cis rs6964587 1.000 rs34043009 chr7:91578447 T/C cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT cis rs7666738 0.830 rs4699594 chr4:98980775 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs72652906 chr8:58188360 C/A cg21724239 chr8:58056113 NA 0.37 4.95 0.41 2.38e-6 Developmental language disorder (linguistic errors); TGCT cis rs734999 0.545 rs12752515 chr1:2564465 T/C cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs2836950 0.545 rs2297256 chr21:40558421 C/T cg11890956 chr21:40555474 PSMG1 -0.66 -6.4 -0.5 2.94e-9 Menarche (age at onset); TGCT cis rs10493773 0.609 rs6689168 chr1:86174232 G/T cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.15 -0.59 3.45e-13 Urate levels in overweight individuals; TGCT cis rs709400 1.000 rs709400 chr14:104149475 A/G cg26031613 chr14:104095156 KLC1 1.13 16.3 0.83 1.26e-32 Body mass index; TGCT cis rs7954584 0.567 rs11043251 chr12:122373279 C/T cg22168489 chr12:122356033 WDR66 0.22 4.78 0.39 4.96e-6 Mean corpuscular volume; TGCT cis rs9388451 0.626 rs1343115 chr6:126069817 C/G cg10911889 chr6:126070802 HEY2 0.5 4.69 0.39 7.17e-6 Brugada syndrome; TGCT cis rs1153858 1.000 rs4775906 chr15:45638294 C/T cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs28386778 0.897 rs4968598 chr17:61835579 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT trans rs66573146 0.808 rs73202120 chr4:7005588 A/G cg07817883 chr1:32538562 TMEM39B 1.31 7.05 0.53 1.08e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs1784581 0.546 rs1954917 chr6:162447490 C/T cg17173639 chr6:162384350 PARK2 0.44 6.1 0.48 1.26e-8 Itch intensity from mosquito bite; TGCT cis rs832540 0.512 rs33320 chr5:56206529 C/T cg24531977 chr5:56204891 C5orf35 -0.55 -5.31 -0.43 4.93e-7 Coronary artery disease; TGCT cis rs7178572 0.568 rs28584877 chr15:77599003 C/A cg22256960 chr15:77711686 NA 0.85 8.73 0.62 1.4e-14 Type 2 diabetes; TGCT cis rs7635838 0.892 rs754015 chr3:11493945 T/C cg00170343 chr3:11313890 ATG7 0.66 6.0 0.47 2.03e-8 HDL cholesterol; TGCT cis rs6582630 0.593 rs7299329 chr12:38447943 G/C cg13010199 chr12:38710504 ALG10B 0.59 4.75 0.39 5.61e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs986417 0.818 rs8008804 chr14:61082357 A/T cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs6964587 0.935 rs28412174 chr7:91577245 T/G cg17063962 chr7:91808500 NA -0.91 -9.99 -0.67 1.32e-17 Breast cancer; TGCT cis rs1218582 0.774 rs4845680 chr1:154863195 A/G cg03351412 chr1:154909251 PMVK 0.52 4.8 0.4 4.51e-6 Prostate cancer; TGCT cis rs2120019 1.000 rs12903201 chr15:75370776 A/C cg11632617 chr15:75315747 PPCDC -0.33 -4.78 -0.39 4.82e-6 Blood trace element (Zn levels); TGCT cis rs2862064 1.000 rs905211 chr5:156447218 A/T cg12943317 chr5:156479607 HAVCR1 -0.39 -5.26 -0.43 6.24e-7 Platelet count; TGCT cis rs11167764 0.895 rs7734160 chr5:141473144 G/T cg23435118 chr5:141488016 NDFIP1 -0.28 -4.58 -0.38 1.1e-5 Crohn's disease; TGCT cis rs732765 0.648 rs8185 chr14:75408789 T/C cg06637938 chr14:75390232 RPS6KL1 -0.65 -4.86 -0.4 3.42e-6 Non-small cell lung cancer; TGCT cis rs7552404 0.696 rs67487205 chr1:76373756 T/C cg22875332 chr1:76189707 ACADM 0.69 6.67 0.51 7.46e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4665809 1.000 rs4665299 chr2:26256840 A/C cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.35e-9 Gut microbiome composition (summer); TGCT cis rs7267979 0.933 rs2258728 chr20:25276343 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7586879 0.593 rs11689543 chr2:25130440 A/T cg01884057 chr2:25150051 NA 0.35 6.87 0.53 2.76e-10 Body mass index; TGCT cis rs4780401 0.609 rs8055247 chr16:11827543 G/A cg01061890 chr16:11836724 TXNDC11 -0.6 -5.71 -0.46 7.73e-8 Rheumatoid arthritis; TGCT cis rs67478160 0.619 rs12878682 chr14:104233627 G/C cg26031613 chr14:104095156 KLC1 -0.63 -6.57 -0.51 1.25e-9 Schizophrenia; TGCT cis rs13064411 0.696 rs7631082 chr3:113208913 C/G cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs67311347 0.955 rs9821036 chr3:40379007 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.63 0.38 9.1e-6 Renal cell carcinoma; TGCT cis rs4851254 0.660 rs4851244 chr2:100671449 C/T cg22139774 chr2:100720529 AFF3 0.45 4.91 0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs1997103 0.863 rs4480062 chr7:55401299 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs67311347 1.000 rs4973989 chr3:40451543 C/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs3833788 1 rs3833788 chr12:121151062 CTCTCTTG/C cg21892295 chr12:121157589 UNC119B -0.24 -5.71 -0.46 7.99e-8 Mean corpuscular hemoglobin; TGCT cis rs2832077 0.506 rs10222093 chr21:30163518 T/C cg24692254 chr21:30365293 RNF160 -0.59 -5.22 -0.42 7.35e-7 Cognitive test performance; TGCT cis rs2204008 0.837 rs1842599 chr12:37986081 G/A cg26384229 chr12:38710491 ALG10B -0.7 -6.12 -0.48 1.11e-8 Bladder cancer; TGCT cis rs12762955 0.687 rs4880470 chr10:1077480 G/A cg18964960 chr10:1102726 WDR37 -0.68 -6.05 -0.48 1.58e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs2841277 0.708 rs2582533 chr14:105398787 G/C cg21017887 chr14:105400489 NA 0.38 5.17 0.42 9.06e-7 Rheumatoid arthritis; TGCT cis rs473651 0.935 rs474478 chr2:239335473 C/T cg08773314 chr2:239334832 ASB1 0.47 7.96 0.58 9.43e-13 Multiple system atrophy; TGCT cis rs3784262 0.692 rs12914388 chr15:58283843 T/C cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.96 -0.47 2.43e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs4665809 0.590 rs66477033 chr2:26472497 T/C cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs7208859 0.623 rs59029591 chr17:29235746 A/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs3784262 0.528 rs4144005 chr15:58330094 C/T cg12031962 chr15:58353849 ALDH1A2 -0.42 -6.28 -0.49 5.09e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs79724016 0.546 rs78410207 chr1:42112627 A/G cg14093106 chr1:42503579 NA -0.63 -4.57 -0.38 1.18e-5 Breast cancer; TGCT cis rs7666738 0.830 rs2903152 chr4:99067992 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2204008 0.774 rs11615665 chr12:38328162 T/A cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs7674212 0.540 rs2720469 chr4:104086484 C/T cg16532752 chr4:104119610 CENPE -0.61 -5.67 -0.45 9.45e-8 Type 2 diabetes; TGCT cis rs11585357 0.793 rs11587669 chr1:17616259 C/T cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs2839186 0.771 rs2280959 chr21:47641996 C/G cg13732083 chr21:47605072 C21orf56 0.37 4.69 0.39 7.07e-6 Testicular germ cell tumor; TGCT cis rs7914558 0.966 rs2297786 chr10:104679978 C/T cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs700590 0.532 rs17558396 chr5:88102281 T/G cg22951263 chr5:87985283 NA -0.52 -5.3 -0.43 5.2e-7 Educational attainment (years of education); TGCT cis rs775227 0.574 rs60279293 chr3:113096087 T/G cg18753928 chr3:113234510 CCDC52 -0.65 -4.77 -0.39 5.12e-6 Dental caries; TGCT cis rs17376456 0.825 rs7715562 chr5:93222034 C/T cg21475434 chr5:93447410 FAM172A -0.63 -4.61 -0.38 9.98e-6 Diabetic retinopathy; TGCT cis rs28395178 1 rs28395178 chr15:78850558 G/A cg24631222 chr15:78858424 CHRNA5 0.97 7.48 0.56 1.17e-11 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs651907 0.557 rs3806653 chr3:101396972 T/C cg12386194 chr3:101231763 SENP7 0.53 5.13 0.42 1.08e-6 Colorectal cancer; TGCT cis rs4144743 0.938 rs35069360 chr17:45321270 C/T cg18085866 chr17:45331354 ITGB3 -0.72 -4.85 -0.4 3.61e-6 Body mass index; TGCT cis rs2730245 0.550 rs2788478 chr7:158672619 A/G cg11984989 chr7:158649758 WDR60 1.02 9.51 0.65 1.95e-16 Height; TGCT cis rs9532580 0.553 rs9549250 chr13:41225229 T/G cg21288729 chr13:41239152 FOXO1 1.02 10.33 0.68 1.95e-18 Mean corpuscular hemoglobin; TGCT cis rs2153535 0.505 rs9405395 chr6:8468622 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.8 0.46 5.19e-8 Motion sickness; TGCT cis rs11578119 0.898 rs12141076 chr1:170379310 T/G cg09767346 chr1:170501363 GORAB 0.74 5.87 0.47 3.81e-8 Male-pattern baldness; TGCT cis rs4654899 0.727 rs11805169 chr1:21156862 A/T cg01072550 chr1:21505969 NA 0.47 6.95 0.53 1.85e-10 Superior frontal gyrus grey matter volume; TGCT cis rs11741688 0.557 rs10043579 chr5:178330174 C/T cg08270223 chr5:178322770 ZFP2 -0.37 -5.49 -0.44 2.14e-7 Sleep duration; TGCT cis rs2762353 0.935 rs3799340 chr6:25762646 C/T cg12310025 chr6:25882481 NA 0.53 5.5 0.44 2.03e-7 Blood metabolite levels; TGCT cis rs6459788 0.693 rs35146559 chr7:157238557 G/A cg03453431 chr7:157225567 NA -0.4 -5.8 -0.46 5.3e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs12464483 0.524 rs2593470 chr2:30887402 G/T cg17749961 chr2:30669863 LCLAT1 0.59 4.58 0.38 1.12e-5 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs853679 0.517 rs9393893 chr6:28109262 T/C cg12963246 chr6:28129442 ZNF389 0.53 5.09 0.42 1.27e-6 Depression; TGCT cis rs3008870 0.920 rs2755253 chr1:67470843 C/T cg11518657 chr1:67396239 MIER1 0.53 4.61 0.38 9.89e-6 Lymphocyte percentage of white cells; TGCT cis rs1862618 0.627 rs744023 chr5:56197078 C/T cg12311346 chr5:56204834 C5orf35 -0.83 -7.48 -0.56 1.18e-11 Initial pursuit acceleration; TGCT cis rs2816062 0.747 rs2816049 chr1:18893768 A/G cg18795169 chr1:18902165 NA -0.6 -14.18 -0.79 1.01e-27 Urate levels in lean individuals; TGCT cis rs68170813 0.559 rs4730232 chr7:106942382 G/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs12497850 0.863 rs4974084 chr3:48939080 G/A cg18654377 chr3:49208889 KLHDC8B -0.41 -5.28 -0.43 5.62e-7 Parkinson's disease; TGCT cis rs950169 0.845 rs4502182 chr15:84923520 A/G cg17173187 chr15:85201210 NMB 0.54 5.55 0.45 1.67e-7 Schizophrenia; TGCT cis rs9911578 1.000 rs2055779 chr17:57030561 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs60994860 chr4:99046753 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11112613 0.713 rs73184082 chr12:105951748 T/C cg03607813 chr12:105948248 NA 0.47 5.72 0.46 7.49e-8 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7804356 1.000 rs6964094 chr7:26834380 C/G cg03456212 chr7:26904342 SKAP2 -0.62 -4.76 -0.39 5.4e-6 Type 1 diabetes; TGCT cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.93 7.44 0.56 1.44e-11 Platelet count; TGCT cis rs7647973 0.516 rs4955419 chr3:49200692 T/A cg07636037 chr3:49044803 WDR6 0.86 8.97 0.63 3.83e-15 Menarche (age at onset); TGCT cis rs6540559 0.673 rs17015361 chr1:210018901 C/G cg21951975 chr1:209979733 IRF6 0.63 4.76 0.39 5.36e-6 Cleft lip with or without cleft palate; TGCT cis rs6733011 0.628 rs981602 chr2:99464275 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.5 -4.95 -0.41 2.33e-6 Bipolar disorder; TGCT cis rs2836974 0.653 rs8130556 chr21:40516872 C/T cg11890956 chr21:40555474 PSMG1 1.11 11.82 0.73 4.61e-22 Cognitive function; TGCT cis rs1981331 0.609 rs7282611 chr21:48043297 C/A cg17243659 chr21:48055224 PRMT2 1.26 6.43 0.5 2.45e-9 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs116975820 0.698 rs11181503 chr12:42827697 A/G cg19980929 chr12:42632907 YAF2 0.61 4.88 0.4 3.14e-6 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs826838 0.967 rs826876 chr12:39123843 T/C cg13010199 chr12:38710504 ALG10B -0.64 -5.07 -0.41 1.39e-6 Heart rate; TGCT cis rs6714710 0.603 rs10432626 chr2:98561153 C/A cg26665480 chr2:98280029 ACTR1B 0.63 5.98 0.47 2.19e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs459571 0.959 rs456205 chr9:136911146 G/A cg14405625 chr9:136855902 VAV2 -0.32 -4.72 -0.39 6.15e-6 Platelet distribution width; TGCT cis rs912057 0.671 rs1294433 chr6:6745163 G/A cg06612196 chr6:6737390 NA 0.47 6.77 0.52 4.57e-10 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs11190604 0.767 rs35508946 chr10:102191156 A/G cg16342193 chr10:102329863 NA -0.38 -5.0 -0.41 1.93e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2235642 0.750 rs2755185 chr16:1645827 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.28 -4.89 -0.4 3.09e-6 Coronary artery disease; TGCT cis rs763121 0.925 rs1056661 chr22:39080245 A/G cg06022373 chr22:39101656 GTPBP1 0.7 6.86 0.52 2.83e-10 Menopause (age at onset); TGCT cis rs6665290 0.868 rs2183836 chr1:227199404 A/T cg10327440 chr1:227177885 CDC42BPA -0.95 -16.62 -0.83 2.46e-33 Myeloid white cell count; TGCT cis rs11018874 0.597 rs4268468 chr11:89886284 C/T cg14505434 chr11:89522851 NA 0.42 4.65 0.39 8.44e-6 White blood cell types; TGCT cis rs4851254 0.660 rs4851250 chr2:100729293 T/C cg04109781 chr2:100722022 AFF3 0.49 4.73 0.39 5.95e-6 Intelligence (multi-trait analysis); TGCT cis rs28374715 0.783 rs11630656 chr15:41570909 T/G cg18705301 chr15:41695430 NDUFAF1 -0.89 -13.95 -0.78 3.49e-27 Ulcerative colitis; TGCT cis rs8056742 0.730 rs12929714 chr16:85093357 C/T cg00229868 chr16:85520891 NA 0.39 4.97 0.41 2.19e-6 Amyotrophic lateral sclerosis; TGCT cis rs67460515 0.926 rs66508859 chr3:160946351 C/T cg03342759 chr3:160939853 NMD3 -0.5 -5.42 -0.44 2.99e-7 Parkinson's disease; TGCT cis rs9911578 1.000 rs9898626 chr17:56698219 C/G cg12560992 chr17:57184187 TRIM37 0.75 9.21 0.64 1.04e-15 Intelligence (multi-trait analysis); TGCT cis rs34014631 0.688 rs17770716 chr10:103574362 C/G cg22630918 chr10:102748988 C10orf2 0.34 4.7 0.39 6.89e-6 Coronary artery calcification; TGCT cis rs4665809 1.000 rs10170359 chr2:26272219 G/T cg22920501 chr2:26401640 FAM59B -0.73 -6.44 -0.5 2.36e-9 Gut microbiome composition (summer); TGCT cis rs4654899 0.802 rs115818417 chr1:21200411 C/T cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4665809 0.590 rs17528653 chr2:26507724 T/C cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs155076 1.000 rs598754 chr13:21845010 C/A cg14456004 chr13:21872349 NA -1.32 -10.82 -0.7 1.25e-19 White matter hyperintensity burden; TGCT cis rs7617773 0.780 rs4130522 chr3:48352313 G/A cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT trans rs561341 0.714 rs547473 chr17:30297560 T/G cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT trans rs916888 0.610 rs199438 chr17:44791643 G/A cg22433210 chr17:43662623 NA 0.94 7.94 0.58 1.05e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs4700695 0.719 rs27587 chr5:65444163 C/T cg21114390 chr5:65439923 SFRS12 -0.84 -7.45 -0.56 1.35e-11 Facial morphology (factor 19); TGCT cis rs12421382 0.507 rs11600810 chr11:109356443 G/A cg27471124 chr11:109292789 C11orf87 0.53 6.33 0.49 4.06e-9 Schizophrenia; TGCT cis rs62064224 0.902 rs17732573 chr17:30627664 C/T cg09324608 chr17:30823087 MYO1D -0.21 -4.57 -0.38 1.17e-5 Schizophrenia; TGCT cis rs9399135 0.967 rs4896125 chr6:135342569 C/T cg24558204 chr6:135376177 HBS1L 0.5 5.0 0.41 1.89e-6 Red blood cell count; TGCT trans rs1005277 0.579 rs1780136 chr10:38501453 A/G cg27523141 chr10:43048294 ZNF37B 0.7 8.15 0.59 3.36e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1801251 1.000 rs13008942 chr2:233594875 G/A cg08000102 chr2:233561755 GIGYF2 0.64 6.53 0.51 1.53e-9 Coronary artery disease; TGCT cis rs7772486 0.790 rs2253768 chr6:146199922 A/G cg05347473 chr6:146136440 FBXO30 0.54 4.99 0.41 1.96e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs765787 0.530 rs12904331 chr15:45518293 C/T cg24006582 chr15:45444508 DUOX1 0.25 5.33 0.43 4.46e-7 Uric acid levels; TGCT cis rs2243480 1.000 rs316334 chr7:65602126 G/T cg18252515 chr7:66147081 NA -1.21 -7.89 -0.58 1.36e-12 Diabetic kidney disease; TGCT cis rs73198271 1.000 rs73198279 chr8:8608504 A/G ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs17001868 0.568 rs10854729 chr22:40750612 T/C cg07138101 chr22:40742427 ADSL 0.71 5.41 0.44 3.08e-7 Mammographic density (dense area); TGCT cis rs6752107 0.901 rs10187752 chr2:234146550 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.58 0.38 1.1e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2404602 0.647 rs12903331 chr15:77168268 C/G cg23625390 chr15:77176239 SCAPER -0.38 -4.96 -0.41 2.22e-6 Blood metabolite levels; TGCT cis rs55823223 0.646 rs55868394 chr17:73851113 C/A cg23806715 chr17:73775811 H3F3B 0.76 5.16 0.42 9.43e-7 Psoriasis; TGCT cis rs2677744 1.000 rs1266483 chr15:91462406 A/G cg22288577 chr15:91498497 RCCD1 0.48 4.88 0.4 3.16e-6 Attention deficit hyperactivity disorder; TGCT cis rs4654899 0.929 rs7515845 chr1:21314455 G/A cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs2299587 0.560 rs11996792 chr8:17781012 C/G cg01800426 chr8:17659068 MTUS1 -0.65 -5.63 -0.45 1.14e-7 Economic and political preferences; TGCT cis rs2762353 0.935 rs1165213 chr6:25799676 A/G cg12310025 chr6:25882481 NA 0.52 5.42 0.44 2.98e-7 Blood metabolite levels; TGCT trans rs17684571 0.938 rs13192037 chr6:56554272 C/A cg14229071 chr15:89282588 NA 0.52 6.63 0.51 9.28e-10 Schizophrenia; TGCT cis rs9910055 0.762 rs184478 chr17:42209751 C/G cg19774624 chr17:42201019 HDAC5 0.83 8.52 0.61 4.64e-14 Total body bone mineral density; TGCT cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.73 0.39 5.95e-6 Schizophrenia; TGCT cis rs17221829 0.733 rs11600011 chr11:89407980 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.44 -0.37 1.96e-5 Anxiety in major depressive disorder; TGCT cis rs11249608 0.548 rs12152869 chr5:178462520 A/G cg21905437 chr5:178450457 ZNF879 0.44 4.55 0.38 1.25e-5 Pubertal anthropometrics; TGCT cis rs7221109 0.560 rs2253717 chr17:38868236 G/A cg07480653 chr17:39868082 GAST -0.23 -5.02 -0.41 1.77e-6 Type 1 diabetes; TGCT cis rs5417 0.689 rs55868524 chr17:7170665 G/A cg25256661 chr17:7137939 DVL2 -0.66 -6.67 -0.51 7.41e-10 Diastolic blood pressure; TGCT cis rs881375 1.000 rs6478486 chr9:123655329 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.34 0.43 4.31e-7 Rheumatoid arthritis; TGCT cis rs2032447 0.869 rs2230655 chr6:26033506 A/G cg03517284 chr6:25882590 NA 0.65 5.87 0.47 3.78e-8 Intelligence (multi-trait analysis); TGCT cis rs17767294 0.708 rs115736281 chr6:27842888 G/A cg08851530 chr6:28072375 NA 1.58 6.9 0.53 2.39e-10 Parkinson's disease; TGCT cis rs10504229 1.000 rs17217082 chr8:58180918 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2204008 0.837 rs11514225 chr12:38076270 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.24 0.43 6.69e-7 Bladder cancer; TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.06 14.7 0.8 5.95e-29 Prudent dietary pattern; TGCT cis rs7568458 0.684 rs67988001 chr2:85787123 C/T cg02493740 chr2:85810744 VAMP5 -0.28 -5.36 -0.43 3.98e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs8032315 0.895 rs4932370 chr15:91404705 A/G cg05180856 chr15:91428056 FES -0.25 -4.61 -0.38 9.88e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4713118 0.621 rs4713134 chr6:28034121 T/C cg12963246 chr6:28129442 ZNF389 0.48 4.79 0.4 4.58e-6 Parkinson's disease; TGCT cis rs1403694 0.695 rs1050274 chr3:186435370 G/A cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs713587 0.520 rs522806 chr2:25316584 C/A cg15423357 chr2:25149977 NA -0.46 -4.46 -0.37 1.83e-5 Body mass index in non-asthmatics; TGCT cis rs3806843 0.607 rs246060 chr5:140324749 T/C cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs1018836 0.923 rs7812970 chr8:91541229 G/A cg16814680 chr8:91681699 NA -0.86 -9.52 -0.65 1.84e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1670533 1.000 rs62294756 chr4:1097676 G/A cg20887711 chr4:1340912 KIAA1530 -0.68 -5.47 -0.44 2.33e-7 Recombination rate (females); TGCT cis rs12681287 0.547 rs6985066 chr8:87526439 A/C cg27223183 chr8:87520930 FAM82B -0.96 -7.03 -0.53 1.21e-10 Caudate activity during reward; TGCT cis rs3733585 0.605 rs4235355 chr4:10123078 C/A cg00071950 chr4:10020882 SLC2A9 -0.51 -5.28 -0.43 5.62e-7 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4409675 0.576 rs11247706 chr1:28213983 G/C cg23691781 chr1:28212827 C1orf38 0.26 5.32 0.43 4.68e-7 Corneal astigmatism; TGCT cis rs28595532 0.748 rs66615663 chr4:119336701 C/T cg21605333 chr4:119757512 SEC24D 0.85 5.43 0.44 2.84e-7 Cannabis dependence symptom count; TGCT cis rs2739330 0.828 rs5751770 chr22:24252842 A/G cg24846343 chr22:24311635 DDTL 0.21 5.22 0.42 7.18e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3806843 0.576 rs405192 chr5:140324710 T/G cg07102913 chr5:140593443 PCDHB13 -0.46 -4.65 -0.39 8.2e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs137699 0.604 rs137702 chr22:39750158 T/C cg24399712 chr22:39784796 NA -0.82 -6.6 -0.51 1.07e-9 IgG glycosylation; TGCT cis rs56104184 0.775 rs56317021 chr19:49395960 C/T cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs875971 1.000 rs709595 chr7:65817333 G/C cg11764359 chr7:65958608 NA 0.62 5.53 0.44 1.82e-7 Aortic root size; TGCT cis rs12959333 0.772 rs12961128 chr18:33306492 C/G cg18885387 chr18:32820922 ZNF397 0.95 4.44 0.37 1.97e-5 Post bronchodilator FEV1; TGCT cis rs12497850 0.864 rs6779394 chr3:49157771 G/A cg06212747 chr3:49208901 KLHDC8B 0.61 5.36 0.43 3.88e-7 Parkinson's disease; TGCT cis rs13102973 0.720 rs4473702 chr4:135851159 C/G cg14419869 chr4:135874104 NA 0.26 4.47 0.37 1.75e-5 Subjective well-being; TGCT cis rs9467711 1.000 rs9467713 chr6:26338128 T/C cg26531700 chr6:26746687 NA -0.94 -5.63 -0.45 1.16e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12210905 0.688 rs72845005 chr6:27492378 T/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs7824557 0.628 rs7815802 chr8:11190647 G/C cg21775007 chr8:11205619 TDH 0.7 6.86 0.52 2.93e-10 Retinal vascular caliber; TGCT cis rs62380364 0.701 rs304138 chr5:88169567 A/G cg22951263 chr5:87985283 NA 0.5 5.02 0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.593 rs6500456 chr16:89888341 T/C cg03388025 chr16:89894329 SPIRE2 0.32 4.72 0.39 6.19e-6 Vitiligo; TGCT cis rs6714788 0.565 rs7599083 chr2:100658077 G/A cg22139774 chr2:100720529 AFF3 -0.41 -6.53 -0.51 1.56e-9 Intelligence (multi-trait analysis); TGCT cis rs28374715 0.662 rs513280 chr15:41482800 T/C cg18705301 chr15:41695430 NDUFAF1 0.75 11.19 0.71 1.6e-20 Ulcerative colitis; TGCT trans rs4650994 0.525 rs4993304 chr1:178535144 A/G cg05059571 chr16:84539110 KIAA1609 -0.54 -11.11 -0.71 2.47e-20 HDL cholesterol levels;HDL cholesterol; TGCT cis rs736408 0.660 rs2019065 chr3:52809525 C/T cg05573699 chr3:52720067 GNL3;PBRM1 0.53 4.83 0.4 3.95e-6 Bipolar disorder; TGCT cis rs9911578 0.967 rs12944948 chr17:56951474 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs4253772 0.638 rs6007845 chr22:46718417 A/T cg24881330 chr22:46731750 TRMU -0.94 -6.36 -0.5 3.54e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs1865760 1.000 rs6910174 chr6:25904414 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs4144743 1.000 rs10438781 chr17:45323819 A/G cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg04317338 chr11:64019027 PLCB3 0.78 6.46 0.5 2.17e-9 Mean platelet volume; TGCT cis rs1218582 0.772 rs10796935 chr1:154891363 G/T cg09359103 chr1:154839909 KCNN3 -0.66 -12.15 -0.74 7.27e-23 Prostate cancer; TGCT cis rs7208859 0.673 rs216418 chr17:28936537 G/A cg19761014 chr17:28927070 LRRC37B2 0.55 4.77 0.39 5.12e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT trans rs62103177 0.789 rs7242289 chr18:77603291 C/T cg05926928 chr17:57297772 GDPD1 1.22 11.62 0.72 1.41e-21 Opioid sensitivity; TGCT cis rs7917772 0.636 rs10786708 chr10:104526245 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 4.6 0.38 1.03e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT trans rs1814175 0.754 rs28593359 chr11:50042357 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs2046867 0.774 rs62249873 chr3:72907115 G/A cg25664220 chr3:72788482 NA -0.55 -7.01 -0.53 1.33e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9916302 0.706 rs7208252 chr17:37584368 A/G cg07936489 chr17:37558343 FBXL20 -0.87 -6.27 -0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs798766 1.000 rs1374469 chr4:1724799 C/T cg05874882 chr4:1763078 NA -0.39 -5.17 -0.42 8.91e-7 Bladder cancer;Urinary bladder cancer; TGCT cis rs8042680 0.554 rs59278520 chr15:91514707 G/A cg23684204 chr15:91497937 RCCD1 0.36 4.67 0.39 7.75e-6 Type 2 diabetes; TGCT cis rs2692947 0.673 rs584811 chr2:97069879 A/G cg23100626 chr2:96804247 ASTL -0.43 -5.51 -0.44 1.99e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs10791323 0.593 rs10791329 chr11:133716356 T/C cg03690763 chr11:133734501 NA -0.32 -4.75 -0.39 5.48e-6 Childhood ear infection; TGCT trans rs7618501 0.902 rs7645061 chr3:49868842 C/T cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs4455778 0.580 rs6952050 chr7:49116354 A/C cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs9611565 0.559 rs6002408 chr22:41967870 C/T cg06634786 chr22:41940651 POLR3H -0.88 -8.32 -0.6 1.36e-13 Vitiligo; TGCT cis rs7666738 0.712 rs11731393 chr4:98859070 G/C cg24818145 chr4:99064322 C4orf37 0.62 4.46 0.37 1.85e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs7659604 0.539 rs11098645 chr4:122729251 G/A cg19748678 chr4:122722346 EXOSC9 0.9 9.34 0.64 4.9e-16 Type 2 diabetes; TGCT cis rs244731 0.959 rs6556307 chr5:176641434 C/T cg06060754 chr5:176797920 RGS14 0.44 6.15 0.48 9.81e-9 Urate levels in lean individuals; TGCT cis rs9549367 0.789 rs9549711 chr13:113900557 C/T cg18105134 chr13:113819100 PROZ -0.34 -5.58 -0.45 1.41e-7 Platelet distribution width; TGCT cis rs3741404 0.560 rs7938819 chr11:63910116 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.78 -7.75 -0.57 2.8e-12 Platelet count; TGCT cis rs7666738 0.830 rs3911282 chr4:99037602 T/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs3008870 1.000 rs12132068 chr1:67451924 G/T cg11518657 chr1:67396239 MIER1 -0.53 -4.6 -0.38 1.04e-5 Lymphocyte percentage of white cells; TGCT cis rs2075371 1.000 rs2075372 chr7:133984432 C/T cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.19e-9 Mean platelet volume; TGCT trans rs2727020 0.595 rs10839286 chr11:49497063 C/A cg11707556 chr5:10655725 ANKRD33B -0.36 -7.03 -0.53 1.25e-10 Coronary artery disease; TGCT cis rs951366 0.903 rs708723 chr1:205739266 C/T cg07167872 chr1:205819463 PM20D1 0.43 4.96 0.41 2.3e-6 Menarche (age at onset); TGCT cis rs7586879 0.964 rs4077680 chr2:25122942 A/G cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs7666738 0.830 rs11725095 chr4:99009711 T/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2933343 0.649 rs728839 chr3:128589359 A/G cg11901034 chr3:128598214 ACAD9 -0.64 -6.11 -0.48 1.16e-8 IgG glycosylation; TGCT cis rs9383153 1.000 rs2073518 chr6:16332730 T/C cg14009473 chr6:15502099 JARID2 0.68 5.73 0.46 7.12e-8 Gambling; TGCT cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg20637647 chr7:64974828 NA 0.89 4.99 0.41 2.01e-6 Diabetic kidney disease; TGCT cis rs595982 0.546 rs10401443 chr19:49402059 C/A cg21252483 chr19:49399788 TULP2 -0.29 -5.12 -0.42 1.13e-6 Red cell distribution width; TGCT trans rs3780486 0.505 rs959749 chr9:33147858 T/C cg04842962 chr6:43655489 MRPS18A 0.8 8.57 0.61 3.51e-14 IgG glycosylation; TGCT cis rs4713118 0.955 rs9468200 chr6:27683063 T/A cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT cis rs854765 0.624 rs9891957 chr17:17744439 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.7 -6.64 -0.51 8.69e-10 Total body bone mineral density; TGCT trans rs4650994 1.000 rs10913570 chr1:178523126 A/C cg05059571 chr16:84539110 KIAA1609 -0.43 -8.0 -0.58 7.66e-13 HDL cholesterol levels;HDL cholesterol; TGCT cis rs910316 1.000 rs12590452 chr14:75548756 T/C cg11812906 chr14:75593930 NEK9 0.74 7.38 0.55 1.97e-11 Height; TGCT cis rs2851682 0.572 rs174570 chr11:61597212 C/T cg19610905 chr11:61596333 FADS2 -0.79 -4.55 -0.38 1.26e-5 Gestational age at birth (child effect);Trans fatty acid levels; TGCT cis rs2797160 0.967 rs2226158 chr6:125995467 C/T cg05901451 chr6:126070800 HEY2 -0.72 -6.76 -0.52 4.77e-10 Endometrial cancer; TGCT cis rs1541995 0.824 rs28670798 chr15:96248345 T/C cg00882281 chr15:96346592 NA 0.3 4.85 0.4 3.7e-6 Photic sneeze reflex; TGCT cis rs3087591 1.000 rs2953015 chr17:29495341 A/G cg24425628 chr17:29625626 OMG;NF1 0.45 6.95 0.53 1.84e-10 Hip circumference; TGCT cis rs1799949 0.896 rs8176098 chr17:41268206 A/C cg05368731 chr17:41323189 NBR1 1.2 14.59 0.79 1.08e-28 Menopause (age at onset); TGCT cis rs1371867 0.875 rs1788169 chr8:101326314 C/T cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs600231 0.542 rs34527830 chr11:65240863 G/A cg17120908 chr11:65337727 SSSCA1 -0.57 -4.45 -0.37 1.9e-5 Bone mineral density; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg01238044 chr22:24384105 GSTT1 -0.5 -4.65 -0.39 8.32e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12893668 0.703 rs4906337 chr14:104040414 C/A cg26031613 chr14:104095156 KLC1 -0.54 -4.44 -0.37 1.97e-5 Reticulocyte count; TGCT cis rs1577917 1.000 rs13217384 chr6:86720000 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.56 -4.77 -0.39 5.06e-6 Response to antipsychotic treatment; TGCT cis rs2066819 1.000 rs2066818 chr12:56753822 C/A cg26714650 chr12:56694279 CS -1.36 -5.89 -0.47 3.4e-8 Psoriasis vulgaris; TGCT cis rs9467711 1.000 rs9467701 chr6:26312170 G/C cg03264133 chr6:25882463 NA -0.82 -4.48 -0.37 1.65e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2191566 0.881 rs1996408 chr19:44532732 G/A cg03039196 chr19:44506973 ZNF230 0.55 4.76 0.39 5.24e-6 Acute lymphoblastic leukemia (childhood); TGCT cis rs838147 0.508 rs507711 chr19:49208564 C/T cg04599840 chr19:48886497 KDELR1 0.23 4.75 0.39 5.54e-6 Dietary macronutrient intake; TGCT cis rs6912958 0.712 rs7772561 chr6:88331299 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs8067545 1.000 rs1860302 chr17:19914399 T/A cg13482628 chr17:19912719 NA 0.55 4.83 0.4 3.98e-6 Schizophrenia; TGCT cis rs4076764 0.914 rs4638099 chr1:163365521 A/G cg24596788 chr1:163392923 NA 0.17 4.79 0.39 4.75e-6 Motion sickness; TGCT cis rs6570726 0.935 rs7757387 chr6:145816726 G/T cg23711669 chr6:146136114 FBXO30 0.7 6.6 0.51 1.09e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6987853 0.931 rs2923399 chr8:42439509 G/A cg20539142 chr8:42623718 CHRNA6 -0.2 -4.82 -0.4 4.2e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs3821902 0.646 rs17344570 chr3:64014239 A/C cg22134162 chr3:63841271 THOC7 0.32 4.85 0.4 3.64e-6 Breast cancer; TGCT cis rs12580194 1.000 rs4262806 chr12:55711562 T/A cg20672549 chr12:56432144 IKZF4 0.26 4.69 0.39 7.12e-6 Cancer; TGCT cis rs6674176 0.597 rs12127737 chr1:44402565 G/A cg13606994 chr1:44402422 ARTN -0.5 -5.47 -0.44 2.36e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1218582 0.774 rs4845683 chr1:154877407 T/C cg16680214 chr1:154839983 KCNN3 -0.42 -9.25 -0.64 8.37e-16 Prostate cancer; TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg16325326 chr1:53192061 ZYG11B 0.57 6.36 0.5 3.5e-9 Monocyte count; TGCT cis rs3820928 0.810 rs10175929 chr2:227858609 T/C cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs17345786 0.911 rs10936707 chr3:101324063 G/A cg11279151 chr3:101281821 RG9MTD1 -0.44 -9.59 -0.65 1.25e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs6811940 chr4:98777898 G/A cg17366294 chr4:99064904 C4orf37 0.65 6.79 0.52 4.13e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs6882046 0.513 rs35148765 chr5:88046158 C/A cg22951263 chr5:87985283 NA -0.55 -5.91 -0.47 3.09e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs9911578 1.000 rs7215808 chr17:56940742 G/C cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs2303745 0.544 rs6512181 chr19:17399213 T/G cg04248312 chr19:17393744 ANKLE1 -0.34 -5.57 -0.45 1.54e-7 Systemic lupus erythematosus; TGCT trans rs6089829 0.962 rs1116450 chr20:61658210 T/C cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs2276314 0.857 rs4799408 chr18:33588982 C/T cg19628046 chr18:33552617 C18orf21 -0.51 -4.47 -0.37 1.74e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs2153535 0.607 rs9502722 chr6:8541483 C/T cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.46e-7 Motion sickness; TGCT cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1577917 0.917 rs35038582 chr6:86721305 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.22 -0.42 7.27e-7 Response to antipsychotic treatment; TGCT cis rs7666738 0.791 rs11097601 chr4:98960103 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs2970818 0.831 rs2909381 chr12:4606527 T/C cg04106436 chr12:8665373 CLEC4D 0.35 6.83 0.52 3.33e-10 Phosphorus levels; TGCT cis rs394563 0.591 rs11155641 chr6:149648595 G/A cg16235748 chr6:149772707 ZC3H12D 0.44 5.14 0.42 1.05e-6 Dupuytren's disease; TGCT trans rs561341 1.000 rs498391 chr17:30328704 G/A cg20587970 chr11:113659929 NA -1.05 -12.8 -0.75 2.04e-24 Hip circumference adjusted for BMI; TGCT cis rs8180040 0.966 rs878659 chr3:47500662 G/A cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT trans rs57221529 0.825 rs72703051 chr5:582997 G/A cg11887960 chr12:57824829 NA 1.17 8.86 0.62 7.09e-15 Lung disease severity in cystic fibrosis; TGCT cis rs2762353 0.776 rs942379 chr6:25849620 A/G cg03264133 chr6:25882463 NA -0.64 -6.81 -0.52 3.66e-10 Blood metabolite levels; TGCT cis rs7666738 0.962 rs2865986 chr4:99067907 A/G cg17366294 chr4:99064904 C4orf37 0.73 6.51 0.5 1.72e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2980439 0.783 rs2955587 chr8:8098079 A/G cg06636001 chr8:8085503 FLJ10661 0.87 8.77 0.62 1.18e-14 Neuroticism; TGCT cis rs17102423 0.723 rs11158573 chr14:65579370 A/G cg11161011 chr14:65562177 MAX -0.53 -7.18 -0.54 5.74e-11 Obesity-related traits; TGCT cis rs1682825 0.790 rs73812277 chr3:10751837 C/A cg23512531 chr3:10780469 NA 0.64 4.55 0.38 1.24e-5 Economic and political preferences (feminism/equality); TGCT cis rs9357506 1.000 rs6910478 chr6:46307341 A/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT trans rs7618501 0.501 rs35275715 chr3:49959148 A/G cg21665057 chr3:196295764 WDR53;FBXO45 0.83 8.58 0.61 3.34e-14 Intelligence (multi-trait analysis); TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg08736216 chr1:53307985 ZYG11A -0.23 -4.56 -0.38 1.19e-5 Monocyte count; TGCT cis rs3008870 0.755 rs2815368 chr1:67500778 C/T cg11518657 chr1:67396239 MIER1 0.47 4.61 0.38 9.68e-6 Lymphocyte percentage of white cells; TGCT cis rs4237845 0.742 rs6650219 chr12:58289100 T/C cg02175503 chr12:58329896 NA 0.52 5.49 0.44 2.17e-7 Intelligence (multi-trait analysis); TGCT trans rs7824557 0.518 rs11250094 chr8:10802001 G/C cg15556689 chr8:8085844 FLJ10661 -0.82 -7.42 -0.55 1.62e-11 Retinal vascular caliber; TGCT cis rs4654899 0.758 rs1609558 chr1:21525228 C/T cg01072550 chr1:21505969 NA 0.57 9.6 0.65 1.15e-16 Superior frontal gyrus grey matter volume; TGCT cis rs28595532 0.920 rs115485705 chr4:119733286 G/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs1580019 0.813 rs2044839 chr7:32500805 A/C cg06627557 chr7:32535165 LSM5;AVL9 0.88 8.48 0.61 5.7e-14 Cognitive ability; TGCT cis rs4757319 0.656 rs10832404 chr11:15347481 A/G cg26427818 chr11:15093613 NA -0.37 -4.56 -0.38 1.2e-5 Breast cancer; TGCT cis rs9611565 0.559 rs132771 chr22:42025350 A/G cg06481639 chr22:41940642 POLR3H 0.73 6.47 0.5 2.04e-9 Vitiligo; TGCT cis rs10782582 0.593 rs17848068 chr1:76190216 G/A cg03433033 chr1:76189801 ACADM -0.58 -6.58 -0.51 1.18e-9 Daytime sleep phenotypes; TGCT cis rs453301 0.686 rs6601280 chr8:8909236 A/T cg08975724 chr8:8085496 FLJ10661 0.58 5.07 0.41 1.38e-6 Joint mobility (Beighton score); TGCT cis rs1401999 0.510 rs3749438 chr3:183705184 G/A cg01324343 chr3:183735012 ABCC5 0.49 5.24 0.43 6.68e-7 Anterior chamber depth; TGCT cis rs7666738 0.830 rs4292342 chr4:98959870 A/T cg05340658 chr4:99064831 C4orf37 0.52 6.01 0.47 1.93e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.765 rs7591992 chr2:99668954 A/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs826838 0.967 rs11169387 chr12:39145737 C/T cg13010199 chr12:38710504 ALG10B 0.82 6.67 0.51 7.41e-10 Heart rate; TGCT cis rs881375 0.678 rs10760125 chr9:123662590 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.48 5.31 0.43 4.92e-7 Rheumatoid arthritis; TGCT cis rs10782582 0.593 rs1412717 chr1:76125471 C/T cg03433033 chr1:76189801 ACADM -0.63 -7.25 -0.55 3.83e-11 Daytime sleep phenotypes; TGCT cis rs1008375 0.932 rs6835077 chr4:17653285 A/T cg10189774 chr4:17578691 LAP3 0.55 4.83 0.4 3.89e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1862618 0.525 rs2662019 chr5:56263104 A/G cg18230493 chr5:56204884 C5orf35 0.65 5.07 0.41 1.41e-6 Initial pursuit acceleration; TGCT cis rs3008870 1.000 rs3008871 chr1:67419089 A/G cg08660285 chr1:67390436 MIER1;WDR78 -1.06 -10.8 -0.7 1.47e-19 Lymphocyte percentage of white cells; TGCT cis rs877282 0.838 rs34912955 chr10:772222 T/C cg17470449 chr10:769945 NA 0.31 4.8 0.4 4.44e-6 Uric acid levels; TGCT cis rs425277 0.628 rs10797427 chr1:2060732 C/T cg24578937 chr1:2090814 PRKCZ -0.24 -5.88 -0.47 3.51e-8 Height; TGCT cis rs2293052 0.697 rs553715 chr12:117753856 G/T cg02962597 chr12:117799749 NOS1 0.27 4.65 0.39 8.28e-6 Schizophrenia; TGCT cis rs838147 0.563 rs281379 chr19:49214274 C/T cg13540341 chr19:49222985 MAMSTR -0.36 -4.64 -0.38 8.64e-6 Dietary macronutrient intake; TGCT cis rs651907 0.557 rs1056579 chr3:101397877 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs17221829 0.668 rs12364732 chr11:89374054 T/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.63 -0.38 9.04e-6 Anxiety in major depressive disorder; TGCT cis rs595982 0.559 rs17206714 chr19:49362001 T/A cg17863274 chr19:49399704 TULP2 -0.48 -6.9 -0.53 2.38e-10 Red cell distribution width; TGCT cis rs2836974 0.831 rs11911149 chr21:40528375 C/T cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs9549260 0.755 rs4943798 chr13:41202948 T/C cg21288729 chr13:41239152 FOXO1 0.97 10.16 0.67 5.23e-18 Red blood cell count; TGCT cis rs5167 0.566 rs2075620 chr19:45480037 C/T cg09555818 chr19:45449301 APOC2 -0.23 -4.62 -0.38 9.53e-6 Blood protein levels; TGCT cis rs1008375 0.931 rs3796814 chr4:17602033 G/C cg10189774 chr4:17578691 LAP3 0.57 4.9 0.4 2.93e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9527 0.590 rs12415388 chr10:104796345 T/C cg04362960 chr10:104952993 NT5C2 0.65 5.59 0.45 1.36e-7 Arsenic metabolism; TGCT cis rs6424115 0.931 rs11800561 chr1:24164398 T/G cg15997130 chr1:24165203 NA 0.9 9.86 0.66 2.77e-17 Immature fraction of reticulocytes; TGCT cis rs7811142 1.000 rs7794485 chr7:100068936 T/C cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs1865760 0.928 rs9295673 chr6:25912094 T/G cg16482183 chr6:26056742 HIST1H1C 0.52 4.58 0.38 1.14e-5 Height; TGCT cis rs1150668 0.799 rs7206 chr6:28201138 A/G cg11262757 chr6:27280423 POM121L2 0.45 4.44 0.37 1.94e-5 Pubertal anthropometrics; TGCT cis rs3731896 0.898 rs72955485 chr2:220152103 C/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.72 4.66 0.39 7.89e-6 Educational attainment; TGCT cis rs10479542 0.896 rs4701130 chr5:178982416 C/T cg05457628 chr5:178986728 RUFY1 -0.44 -4.91 -0.4 2.84e-6 Lung cancer; TGCT cis rs2486288 0.656 rs7171312 chr15:45570225 C/G cg26924012 chr15:45694286 SPATA5L1 -0.78 -7.55 -0.56 8e-12 Glomerular filtration rate; TGCT cis rs2932538 0.922 rs7535636 chr1:113101799 C/T cg22162597 chr1:113214053 CAPZA1 -0.27 -5.98 -0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs2239547 0.521 rs9682464 chr3:52888485 C/T cg10802521 chr3:52805072 NEK4 -0.65 -6.14 -0.48 1.02e-8 Schizophrenia; TGCT cis rs4494114 0.967 rs6660891 chr1:39319009 C/T cg25970120 chr1:39325951 RRAGC -0.6 -6.28 -0.49 5.09e-9 Blood protein levels; TGCT cis rs12620999 0.941 rs62183343 chr2:237979163 T/C cg23555395 chr2:238036564 NA 0.27 4.76 0.39 5.28e-6 Systemic lupus erythematosus; TGCT cis rs992157 0.700 rs10165153 chr2:219159629 T/C cg00012203 chr2:219082015 ARPC2 0.81 8.08 0.59 4.97e-13 Colorectal cancer; TGCT cis rs6430585 0.528 rs79826902 chr2:136670419 G/A cg07169764 chr2:136633963 MCM6 1.25 12.39 0.74 1.91e-23 Corneal structure; TGCT cis rs362272 0.524 rs2749781 chr4:3346617 T/C cg18352616 chr4:3374830 RGS12 0.26 5.25 0.43 6.33e-7 Serum sulfate level; TGCT cis rs12477438 0.798 rs6705583 chr2:99602625 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 -0.67 -5.89 -0.47 3.39e-8 Chronic sinus infection; TGCT cis rs1903068 0.853 rs12505096 chr4:56006102 C/A cg09978860 chr4:56023921 NA 0.58 6.22 0.49 6.84e-9 Endometriosis; TGCT cis rs6951245 0.507 rs11763865 chr7:1194274 G/A cg18402987 chr7:1209562 NA 0.52 4.76 0.39 5.3e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4253772 0.513 rs6008700 chr22:46722560 C/T cg26492175 chr22:47022658 GRAMD4 0.19 4.5 0.37 1.54e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs7945705 0.967 rs1569408 chr11:8909732 G/A cg21881798 chr11:8931708 C11orf17;ST5 0.42 4.7 0.39 6.86e-6 Hemoglobin concentration; TGCT cis rs7647973 0.925 rs9881860 chr3:49352522 A/T cg06212747 chr3:49208901 KLHDC8B 0.6 4.71 0.39 6.63e-6 Menarche (age at onset); TGCT trans rs9929218 0.551 rs2296409 chr16:68713730 G/A cg04657470 chr2:198365150 HSPE1;HSPD1 0.62 8.2 0.59 2.51e-13 Colorectal cancer; TGCT cis rs911555 0.755 rs17841064 chr14:103900609 A/G cg12935359 chr14:103987150 CKB -0.33 -4.47 -0.37 1.76e-5 Intelligence (multi-trait analysis); TGCT cis rs2742234 0.910 rs2505511 chr10:43641029 T/A cg02780029 chr10:43622663 RET -0.26 -5.09 -0.42 1.28e-6 Hirschsprung disease; TGCT cis rs68170813 0.652 rs7784906 chr7:107148386 C/T cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs1045529 0.524 rs34251783 chr8:8891376 T/C cg00184457 chr8:8946301 NA -0.26 -4.94 -0.41 2.45e-6 Myopia;Myopia (pathological); TGCT cis rs4555082 0.834 rs2735819 chr14:105713449 C/T cg01266790 chr14:105781312 PACS2 0.55 4.51 0.38 1.49e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs2692947 0.702 rs2312955 chr2:96777168 T/G cg23100626 chr2:96804247 ASTL -0.42 -5.0 -0.41 1.92e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7811142 1.000 rs7787620 chr7:100089234 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.44 0.56 1.45e-11 Platelet count; TGCT cis rs7542091 1.000 rs7542091 chr1:210031948 G/C cg22029157 chr1:209979665 IRF6 0.57 5.64 0.45 1.1e-7 Monobrow; TGCT cis rs12142240 0.731 rs6681857 chr1:46850124 T/C cg00530320 chr1:46809349 NSUN4 0.29 5.83 0.46 4.57e-8 Menopause (age at onset); TGCT cis rs933688 1.000 rs933688 chr5:90762748 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.58 0.69 4.94e-19 Smoking behavior; TGCT cis rs4285028 0.948 rs34566912 chr3:121679626 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs10540 1.000 rs61876339 chr11:495283 T/C cg03934478 chr11:495069 RNH1 0.35 5.82 0.46 4.66e-8 Body mass index; TGCT cis rs60154123 0.505 rs2206043 chr1:210042983 G/A cg22029157 chr1:209979665 IRF6 0.79 5.78 0.46 5.6e-8 Coronary artery disease; TGCT cis rs13064411 0.696 rs2087129 chr3:113142769 T/A cg10517650 chr3:113235015 CCDC52 -0.35 -4.69 -0.39 7.18e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs904251 0.523 rs2776870 chr6:37481364 C/A cg08126542 chr6:37504118 NA -0.44 -6.51 -0.5 1.71e-9 Cognitive performance; TGCT cis rs6840360 0.550 rs6816471 chr4:152494869 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs4927850 0.958 rs1975582 chr3:195751439 G/T cg02975922 chr3:195473998 MUC4 -0.24 -5.47 -0.44 2.4e-7 Pancreatic cancer; TGCT cis rs28386778 0.897 rs2028567 chr17:61915326 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs11586313 0.507 rs2339385 chr1:152859594 C/G cg07796016 chr1:152779584 LCE1C -0.41 -4.56 -0.38 1.2e-5 Vitamin D levels; TGCT cis rs3008870 0.959 rs56707923 chr1:67388016 T/C cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs9902453 0.904 rs4528633 chr17:28356136 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.81 -7.67 -0.57 4.37e-12 Coffee consumption (cups per day); TGCT cis rs60154123 0.505 rs76101197 chr1:210044089 T/C cg21951975 chr1:209979733 IRF6 0.69 5.18 0.42 8.74e-7 Coronary artery disease; TGCT cis rs4665809 1.000 rs4665309 chr2:26335502 T/C cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs7811142 1.000 rs11763414 chr7:100016844 C/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs9926296 0.643 rs2159114 chr16:89831841 A/G cg26513180 chr16:89883248 FANCA 0.72 7.02 0.53 1.3e-10 Vitiligo; TGCT cis rs1538970 0.851 rs2055145 chr1:45926495 C/G cg05343316 chr1:45956843 TESK2 0.81 6.81 0.52 3.79e-10 Platelet count; TGCT cis rs11122272 0.735 rs2474623 chr1:231513993 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT cis rs2795502 0.873 rs2077626 chr10:43410962 A/G cg20628663 chr10:43360327 NA 0.36 5.47 0.44 2.33e-7 Blood protein levels; TGCT cis rs7100689 0.646 rs1340375 chr10:82129039 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs9788721 0.614 rs951984 chr15:78720915 T/A cg18825076 chr15:78729989 IREB2 -0.33 -4.88 -0.4 3.13e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs986417 1.000 rs1474999 chr14:60905920 T/C cg27398547 chr14:60952738 C14orf39 -1.39 -10.61 -0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs916888 0.773 rs199451 chr17:44801784 G/A cg15921436 chr17:44337874 NA 0.58 8.15 0.59 3.34e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7944584 0.551 rs12224672 chr11:47500400 C/T cg20307385 chr11:47447363 PSMC3 0.9 8.5 0.61 5.08e-14 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs28386778 0.863 rs2727355 chr17:61931790 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs9660180 0.875 rs4648727 chr1:1776269 C/A cg27541892 chr1:1571801 CDK11B -0.4 -5.3 -0.43 5.09e-7 Body mass index; TGCT cis rs7714584 1.000 rs10051924 chr5:150226639 T/C cg22134413 chr5:150180641 NA 0.87 6.89 0.53 2.52e-10 Crohn's disease; TGCT cis rs28595532 0.668 rs56410164 chr4:119331625 A/G cg21605333 chr4:119757512 SEC24D 0.87 5.49 0.44 2.14e-7 Cannabis dependence symptom count; TGCT cis rs9611565 0.512 rs139562 chr22:42196684 G/C cg06634786 chr22:41940651 POLR3H -0.81 -7.49 -0.56 1.1e-11 Vitiligo; TGCT cis rs362272 0.524 rs7435601 chr4:3369645 A/G cg22655196 chr4:3374909 RGS12 0.22 4.6 0.38 1.03e-5 Serum sulfate level; TGCT cis rs9926296 0.744 rs164747 chr16:89708680 T/G cg27121462 chr16:89883253 FANCA -0.5 -4.61 -0.38 9.76e-6 Vitiligo; TGCT cis rs250677 0.687 rs250667 chr5:148455134 A/G cg23229984 chr5:148520753 ABLIM3 -0.22 -4.95 -0.41 2.38e-6 Breast cancer; TGCT trans rs7819412 0.511 rs10108511 chr8:11435516 T/C cg15556689 chr8:8085844 FLJ10661 -0.78 -7.4 -0.55 1.79e-11 Triglycerides; TGCT cis rs9653442 0.900 rs1160544 chr2:100832218 A/C cg07810366 chr2:100720526 AFF3 -0.39 -5.97 -0.47 2.3e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs17376456 0.597 rs1031423 chr5:93276883 A/G cg21475434 chr5:93447410 FAM172A -0.64 -6.0 -0.47 1.99e-8 Diabetic retinopathy; TGCT cis rs72945132 0.882 rs67822447 chr11:70230972 G/T cg00319359 chr11:70116639 PPFIA1 1.04 7.94 0.58 1.03e-12 Coronary artery disease; TGCT cis rs3813567 0.759 rs12595350 chr15:78953464 G/A cg24631222 chr15:78858424 CHRNA5 0.68 4.72 0.39 6.35e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT trans rs561341 0.556 rs118032208 chr17:30395634 T/C cg20587970 chr11:113659929 NA -0.98 -8.12 -0.59 3.87e-13 Hip circumference adjusted for BMI; TGCT cis rs2963155 0.518 rs853177 chr5:142635460 A/G cg17617527 chr5:142782415 NR3C1 0.83 6.17 0.48 8.99e-9 Breast cancer; TGCT cis rs17270561 0.578 rs76182885 chr6:25904085 G/C cg16482183 chr6:26056742 HIST1H1C 0.94 7.33 0.55 2.58e-11 Iron status biomarkers; TGCT cis rs28595532 0.688 rs116566508 chr4:119619195 G/A cg14228332 chr4:119757509 SEC24D 1.0 5.76 0.46 6.22e-8 Cannabis dependence symptom count; TGCT cis rs597539 0.652 rs592697 chr11:68650064 G/A cg06112835 chr11:68658793 MRPL21 0.47 8.03 0.59 6.25e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9443189 0.570 rs72884926 chr6:76266208 T/C cg01950844 chr6:76311363 SENP6 0.95 5.82 0.46 4.69e-8 Prostate cancer; TGCT cis rs11098499 0.730 rs78971550 chr4:120281041 C/T cg09307838 chr4:120376055 NA 0.56 5.41 0.44 3.18e-7 Corneal astigmatism; TGCT cis rs739496 0.579 rs73426310 chr12:112342410 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs4704846 1.000 rs919744 chr5:156531254 G/C cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs2239547 0.657 rs3755803 chr3:52866157 C/G cg10802521 chr3:52805072 NEK4 -0.63 -5.99 -0.47 2.16e-8 Schizophrenia; TGCT cis rs35146811 0.735 rs1727139 chr7:99815367 C/T cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs782590 0.837 rs782584 chr2:55921116 C/G cg18811423 chr2:55921094 PNPT1 -0.73 -8.31 -0.6 1.38e-13 Metabolic syndrome; TGCT trans rs7824557 0.564 rs2572395 chr8:11235360 A/C cg15556689 chr8:8085844 FLJ10661 -0.76 -6.96 -0.53 1.75e-10 Retinal vascular caliber; TGCT cis rs2033711 0.870 rs4801583 chr19:58918405 A/G cg12042659 chr19:58951599 ZNF132 0.51 4.67 0.39 7.69e-6 Uric acid clearance; TGCT cis rs6951245 1.000 rs79422648 chr7:1080241 T/C cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17122693 0.551 rs2934685 chr14:51050865 C/G cg04730355 chr14:51134070 SAV1 1.2 12.06 0.73 1.23e-22 Cognitive performance; TGCT cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg14827481 chr10:134361889 INPP5A 0.3 4.82 0.4 4.18e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs8020441 0.891 rs61362797 chr14:51167752 A/T cg04730355 chr14:51134070 SAV1 0.71 5.77 0.46 5.92e-8 Cognitive performance; TGCT cis rs3771570 1.000 rs55634485 chr2:242268994 T/C cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs250677 0.687 rs36044 chr5:148441128 T/C cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs4862750 0.914 rs7658351 chr4:187875680 G/T cg03452623 chr4:187889614 NA -0.37 -5.55 -0.45 1.63e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs896854 0.684 rs10099941 chr8:95987008 C/T cg13393036 chr8:95962371 TP53INP1 -0.58 -7.97 -0.58 8.83e-13 Type 2 diabetes; TGCT cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs12142240 0.698 rs67276232 chr1:46825484 T/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs4455778 0.580 rs4492325 chr7:49096154 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT trans rs208520 0.634 rs3909071 chr6:66836947 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.15e-18 Exhaled nitric oxide output; TGCT cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.91 7.47 0.56 1.26e-11 Platelet count; TGCT cis rs7949030 0.591 rs12049914 chr11:62369436 C/G cg11742103 chr11:62369870 EML3;MTA2 0.61 8.75 0.62 1.29e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3935685 0.934 rs61331678 chr15:77995949 G/C cg03457338 chr15:78040120 NA -0.22 -5.17 -0.42 9.25e-7 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg06481639 chr22:41940642 POLR3H 0.75 6.64 0.51 8.81e-10 Vitiligo; TGCT cis rs2933343 1.000 rs1683778 chr3:128644595 A/G cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs6570726 0.935 rs449377 chr6:145852437 C/G cg23711669 chr6:146136114 FBXO30 0.69 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 1.000 rs6089828 chr20:61668998 C/T cg18188782 chr20:61659543 NA 0.46 5.49 0.44 2.13e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs68170813 0.652 rs17403088 chr7:107111373 C/A cg02696742 chr7:106810147 HBP1 -0.64 -4.84 -0.4 3.8e-6 Coronary artery disease; TGCT cis rs17345786 0.953 rs78645744 chr3:101327789 T/A cg12386194 chr3:101231763 SENP7 0.61 5.66 0.45 9.91e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs13217239 0.646 rs4269366 chr6:27016413 C/T cg15659132 chr6:26577336 NA 0.54 5.34 0.43 4.32e-7 Schizophrenia; TGCT cis rs3733585 0.699 rs6844316 chr4:9958977 A/G cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs72843506 0.722 rs74658636 chr17:20197982 A/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.86 -0.4 3.54e-6 Schizophrenia; TGCT cis rs2180341 0.814 rs6905553 chr6:127727407 A/G cg27446573 chr6:127587934 RNF146 0.88 8.07 0.59 5.22e-13 Breast cancer; TGCT cis rs10540 1.000 rs61876336 chr11:489537 C/T cg03934478 chr11:495069 RNH1 0.36 5.98 0.47 2.19e-8 Body mass index; TGCT cis rs7666738 0.830 rs10022389 chr4:99022229 T/C cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.800 rs4819045 chr21:46660138 C/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 0.683 rs11774645 chr8:58132921 G/C cg20607798 chr8:58055168 NA 0.61 5.16 0.42 9.38e-7 Developmental language disorder (linguistic errors); TGCT cis rs1005277 0.579 rs1985707 chr10:38434098 C/T cg13531842 chr10:38383804 ZNF37A -0.39 -4.66 -0.39 8.06e-6 Extrinsic epigenetic age acceleration; TGCT cis rs9926296 0.568 rs886950 chr16:89836872 T/C cg26513180 chr16:89883248 FANCA 1.06 14.89 0.8 2.22e-29 Vitiligo; TGCT cis rs28595532 0.920 rs116231457 chr4:119762396 A/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs4727027 0.866 rs1358062 chr7:148783743 T/C cg23583168 chr7:148888333 NA -0.69 -8.76 -0.62 1.23e-14 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs7208859 0.673 rs450585 chr17:28951039 G/A cg14008862 chr17:28927542 LRRC37B2 0.69 4.46 0.37 1.84e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.830 rs1813972 chr4:98886828 C/A cg05340658 chr4:99064831 C4orf37 0.52 6.02 0.48 1.81e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 1.000 rs12146051 chr1:46742952 G/C cg00530320 chr1:46809349 NSUN4 0.25 4.92 0.4 2.68e-6 Menopause (age at onset); TGCT cis rs514406 0.667 rs10788942 chr1:53210521 A/T cg25767906 chr1:53392781 SCP2 0.46 5.11 0.42 1.19e-6 Monocyte count; TGCT cis rs13082711 0.522 rs551621 chr3:27336325 G/C cg02860705 chr3:27208620 NA 0.33 5.45 0.44 2.62e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs875971 0.895 rs7788984 chr7:65915616 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs6061231 0.544 rs2427314 chr20:60973666 C/T cg15674680 chr20:60982522 CABLES2 0.72 6.16 0.48 9.26e-9 Colorectal cancer; TGCT cis rs1633360 1 rs1633360 chr12:58108052 C/T cg15848620 chr12:58087721 OS9 -0.58 -4.89 -0.4 3.12e-6 Rheumatoid arthritis; TGCT cis rs3902035 1.000 rs3902035 chr6:119000232 T/C cg07617317 chr6:118971624 C6orf204 0.48 5.52 0.44 1.87e-7 QT interval; TGCT cis rs2745967 0.505 rs607952 chr1:208053785 T/C cg22525895 chr1:207977042 MIR29B2 0.37 5.65 0.45 1.02e-7 Resting heart rate; TGCT cis rs1218582 0.772 rs1976559 chr1:154879788 A/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs875971 1.000 rs6958277 chr7:65979349 A/G cg11764359 chr7:65958608 NA 0.61 5.54 0.45 1.76e-7 Aortic root size; TGCT cis rs950776 0.518 rs12910289 chr15:78822065 T/G cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs344364 0.511 rs2917515 chr16:1945271 G/C cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs2469997 1.000 rs2447178 chr8:120356188 C/T cg00681363 chr8:120844660 TAF2 0.65 4.52 0.38 1.45e-5 Hypertension (SNP x SNP interaction); TGCT cis rs28595532 0.920 rs116149978 chr4:119761069 A/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2255336 0.938 rs1478310 chr12:10534878 C/T cg16084090 chr12:10586130 KLRC2 0.27 4.45 0.37 1.9e-5 Blood protein levels; TGCT cis rs1799949 1.000 rs8176318 chr17:41197274 G/T cg23758822 chr17:41437982 NA 0.79 7.6 0.56 6.31e-12 Menopause (age at onset); TGCT cis rs7267979 1.000 rs2257496 chr20:25279315 A/G cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3806843 0.518 rs173471 chr5:140335226 A/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs295137 0.798 rs295142 chr2:201211716 C/T cg23649088 chr2:200775458 C2orf69 -0.28 -4.67 -0.39 7.68e-6 Asthma (bronchodilator response); TGCT cis rs11077998 0.933 rs3736204 chr17:80530279 C/T cg10255544 chr17:80519551 FOXK2 0.23 4.44 0.37 1.97e-5 Reticulocyte fraction of red cells; TGCT cis rs17253792 0.822 rs45501402 chr14:56140115 C/T cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs17473412 0.787 rs10069343 chr5:122705535 C/T cg15125798 chr5:122621645 NA -0.57 -5.15 -0.42 9.93e-7 Total body bone mineral density; TGCT trans rs1814175 0.781 rs11040681 chr11:49981654 G/T cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs829883 0.738 rs249846 chr12:98868739 T/C cg25150519 chr12:98850993 NA 0.64 7.83 0.58 1.84e-12 Colorectal adenoma (advanced); TGCT cis rs62064224 0.791 rs2344977 chr17:30720573 C/G cg25809561 chr17:30822961 MYO1D 0.32 5.42 0.44 3.01e-7 Schizophrenia; TGCT cis rs4711350 0.765 rs1318691 chr6:33761884 G/A cg18005901 chr6:33739558 LEMD2 -0.58 -6.48 -0.5 1.96e-9 Schizophrenia; TGCT cis rs916888 0.773 rs199445 chr17:44817408 C/T cg17911788 chr17:44343683 NA -0.67 -7.15 -0.54 6.59e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2180341 0.920 rs1073932 chr6:127682009 G/T cg24812749 chr6:127587940 RNF146 0.93 7.4 0.55 1.83e-11 Breast cancer; TGCT cis rs66573146 0.803 rs59742225 chr4:6969942 C/T cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs7811142 1.000 rs28490152 chr7:100020982 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs17767294 0.708 rs72847377 chr6:27866189 C/T cg08851530 chr6:28072375 NA 1.57 7.27 0.55 3.59e-11 Parkinson's disease; TGCT cis rs7845219 0.544 rs2123647 chr8:95931782 A/G cg16049864 chr8:95962084 TP53INP1 0.46 5.06 0.41 1.47e-6 Type 2 diabetes; TGCT cis rs1878931 0.507 rs8054222 chr16:3413477 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.62 -4.89 -0.4 3.1e-6 Body mass index (adult); TGCT cis rs1692580 0.777 rs7547453 chr1:2195117 C/T cg24578937 chr1:2090814 PRKCZ 0.2 4.56 0.38 1.22e-5 Coronary artery disease; TGCT cis rs317689 0.690 rs317646 chr12:69657145 A/G cg14784868 chr12:69753453 YEATS4 -0.53 -4.51 -0.38 1.5e-5 Response to diuretic therapy; TGCT cis rs10782582 0.609 rs11161848 chr1:76367722 A/G cg03433033 chr1:76189801 ACADM -0.5 -4.91 -0.4 2.81e-6 Daytime sleep phenotypes; TGCT cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg11890956 chr21:40555474 PSMG1 1.13 12.1 0.74 1e-22 Cognitive function; TGCT cis rs66561647 0.563 rs4733580 chr8:128932677 G/A cg11792826 chr8:129160931 MIR1208 0.23 5.07 0.41 1.4e-6 Hemoglobin concentration; TGCT cis rs9388451 0.868 rs1268083 chr6:126049040 T/C cg05901451 chr6:126070800 HEY2 1.01 12.85 0.76 1.47e-24 Brugada syndrome; TGCT cis rs75686122 0.892 rs76423444 chr8:104714028 G/A cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs13256369 1.000 rs10095733 chr8:8574646 A/G cg18904891 chr8:8559673 CLDN23 0.64 5.89 0.47 3.36e-8 Obesity-related traits; TGCT cis rs28595532 0.920 rs115860303 chr4:119734526 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs7731657 0.537 rs2189504 chr5:130298900 C/A cg08523029 chr5:130500466 HINT1 -0.58 -4.84 -0.4 3.8e-6 Fasting plasma glucose; TGCT trans rs208520 0.661 rs1776361 chr6:66822270 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.97 -10.47 -0.69 9.18e-19 Exhaled nitric oxide output; TGCT cis rs9868809 0.881 rs57334642 chr3:48666795 C/T cg00383909 chr3:49044727 WDR6 0.97 5.08 0.42 1.34e-6 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs3125734 0.572 rs7896627 chr10:64046354 T/G cg19640130 chr10:64028056 RTKN2 -0.38 -4.79 -0.39 4.73e-6 Rheumatoid arthritis; TGCT cis rs8017423 0.967 rs4900030 chr14:90689813 T/A cg04374321 chr14:90722782 PSMC1 0.77 8.03 0.58 6.42e-13 Mortality in heart failure; TGCT cis rs2153535 0.580 rs9505450 chr6:8469902 C/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1348850 0.914 rs4893938 chr2:178250095 T/C cg22681709 chr2:178499509 PDE11A -0.35 -4.57 -0.38 1.15e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs12762955 0.507 rs10737004 chr10:1039019 T/C cg26597838 chr10:835615 NA -0.48 -6.43 -0.5 2.45e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs12893668 0.572 rs4900590 chr14:104146421 C/T cg26031613 chr14:104095156 KLC1 -0.59 -5.05 -0.41 1.51e-6 Reticulocyte count; TGCT cis rs8017423 0.935 rs11624295 chr14:90695612 T/G cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT trans rs916888 0.773 rs199448 chr17:44809001 A/G cg22968622 chr17:43663579 NA 1.28 12.17 0.74 6.65e-23 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1008375 1.000 rs7661631 chr4:17679751 T/C cg10189774 chr4:17578691 LAP3 -0.53 -4.69 -0.39 7.14e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs78487399 0.908 rs75664918 chr2:43839090 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.64 4.63 0.38 8.92e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs303386 0.501 rs6703819 chr1:99574494 T/C cg03593336 chr1:99471295 LPPR5 0.26 5.33 0.43 4.4e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (all topoisomerase inhibitors);Adverse response to chemotherapy (neutropenia/leucopenia) (camptothecin); TGCT cis rs10504229 0.906 rs7006539 chr8:58178799 A/T cg24829409 chr8:58192753 C8orf71 -0.54 -5.03 -0.41 1.68e-6 Developmental language disorder (linguistic errors); TGCT cis rs7829975 0.658 rs2409096 chr8:8692477 T/C cg08975724 chr8:8085496 FLJ10661 0.56 5.04 0.41 1.57e-6 Mood instability; TGCT cis rs77880822 0.562 rs6078405 chr20:1247246 T/C cg23117778 chr20:1206693 RAD21L1 0.7 4.51 0.38 1.48e-5 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs2293052 0.757 rs567581 chr12:117757512 C/T cg02962597 chr12:117799749 NOS1 0.26 4.56 0.38 1.21e-5 Schizophrenia; TGCT cis rs7523273 0.565 rs12733108 chr1:207887210 C/T cg22525895 chr1:207977042 MIR29B2 0.35 5.75 0.46 6.66e-8 Schizophrenia; TGCT cis rs7914558 1.000 rs7067970 chr10:104913870 C/T cg15744005 chr10:104629667 AS3MT -0.42 -5.24 -0.43 6.69e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs9868809 0.772 rs9841602 chr3:48713570 A/G cg00383909 chr3:49044727 WDR6 0.88 5.29 0.43 5.32e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs2204008 0.837 rs11180821 chr12:38242843 A/G cg13010199 chr12:38710504 ALG10B 0.6 4.64 0.38 8.72e-6 Bladder cancer; TGCT cis rs881375 1.000 rs881375 chr9:123652898 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.5 5.5 0.44 2.03e-7 Rheumatoid arthritis; TGCT cis rs2721195 0.967 rs11777703 chr8:145703508 G/A cg15857475 chr8:145742913 RECQL4;LRRC14 -0.86 -9.53 -0.65 1.75e-16 Age at first birth; TGCT cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg03806693 chr22:41940476 POLR3H 1.04 10.94 0.7 6.42e-20 Crohn's disease;Inflammatory bowel disease; TGCT cis rs4319547 0.695 rs11057797 chr12:122860732 G/A cg08088222 chr12:122070432 ORAI1 -0.25 -4.49 -0.37 1.58e-5 Body mass index; TGCT cis rs950776 0.518 rs2292117 chr15:78834689 C/T cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs7524258 0.903 rs4908450 chr1:7292756 T/C cg07173049 chr1:7289937 CAMTA1 0.32 5.31 0.43 4.88e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs28386778 0.897 rs11079510 chr17:61820902 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs1018836 0.886 rs10956750 chr8:91621704 G/C cg16814680 chr8:91681699 NA -0.86 -9.19 -0.64 1.12e-15 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT trans rs2288327 0.557 rs7577862 chr2:179352857 G/A cg14011486 chr1:26737247 LIN28 1.03 7.28 0.55 3.41e-11 Atrial fibrillation; TGCT cis rs669446 0.533 rs3791041 chr1:44202991 A/G cg12908607 chr1:44402522 ARTN -0.61 -6.99 -0.53 1.52e-10 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs921968 0.541 rs647990 chr2:219441428 T/C cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs10484885 0.571 rs17708151 chr6:90632293 T/C cg10278699 chr6:90661155 BACH2 0.31 4.51 0.38 1.49e-5 QRS interval (sulfonylurea treatment interaction); TGCT cis rs12477438 0.520 rs6542863 chr2:99725138 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs682748 0.901 rs999990 chr5:17122228 C/T cg23987134 chr5:17158319 LOC285696 -0.19 -4.48 -0.37 1.66e-5 Hippocampal atrophy; TGCT cis rs7246657 0.943 rs2303131 chr19:37936025 G/A cg18154014 chr19:37997991 ZNF793 0.95 6.63 0.51 9.39e-10 Coronary artery calcification; TGCT cis rs4862750 0.872 rs6836781 chr4:187899701 G/A cg22105103 chr4:187893119 NA 0.35 4.89 0.4 3.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs17401966 0.867 rs6696056 chr1:10305992 C/A cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs7017914 0.967 rs1348535 chr8:71662741 A/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.05 -0.41 1.56e-6 Bone mineral density; TGCT cis rs9926296 0.568 rs1230 chr16:89804855 A/G cg21285383 chr16:89894308 SPIRE2 -0.44 -6.82 -0.52 3.48e-10 Vitiligo; TGCT cis rs12681288 0.823 rs4735974 chr8:1000218 T/G cg04851639 chr8:1020857 NA -0.36 -6.43 -0.5 2.55e-9 Schizophrenia; TGCT cis rs3916 0.911 rs34673751 chr12:121171891 G/A cg21892295 chr12:121157589 UNC119B -0.22 -4.45 -0.37 1.89e-5 Urinary metabolites (H-NMR features); TGCT cis rs34245846 0.769 rs12729486 chr1:154827366 T/C cg06418219 chr1:154948305 SHC1;CKS1B 0.73 5.86 0.47 3.83e-8 Atrial fibrillation; TGCT cis rs3784262 0.740 rs1372369 chr15:58294381 T/G cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.3 -0.49 4.77e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg06212747 chr3:49208901 KLHDC8B 0.6 5.44 0.44 2.75e-7 Parkinson's disease; TGCT cis rs7833790 0.724 rs6473310 chr8:82707981 A/G cg27398817 chr8:82754497 SNX16 -0.73 -6.03 -0.48 1.75e-8 Diastolic blood pressure; TGCT cis rs7618915 0.571 rs6805539 chr3:52609710 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs4478037 0.822 rs9868526 chr3:33124269 A/G cg19404215 chr3:33155277 CRTAP -0.98 -5.13 -0.42 1.1e-6 Major depressive disorder; TGCT cis rs10504229 0.683 rs6998040 chr8:58110155 G/T cg02725872 chr8:58115012 NA 0.36 5.0 0.41 1.94e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs2865979 chr4:99027137 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs832540 0.931 rs33319 chr5:56206675 C/A cg12311346 chr5:56204834 C5orf35 -0.48 -5.14 -0.42 1.06e-6 Coronary artery disease; TGCT cis rs6882046 0.513 rs616391 chr5:88038845 C/T cg22951263 chr5:87985283 NA -0.55 -5.9 -0.47 3.27e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs7727544 0.507 rs11741341 chr5:131570218 A/G cg24060327 chr5:131705240 SLC22A5 -0.58 -6.04 -0.48 1.64e-8 Blood metabolite levels; TGCT cis rs8180040 0.681 rs9818382 chr3:47193034 C/T cg27129171 chr3:47204927 SETD2 0.71 8.5 0.61 5.06e-14 Colorectal cancer; TGCT cis rs1403694 0.966 rs1648715 chr3:186439618 A/G cg12454167 chr3:186435060 KNG1 0.42 7.32 0.55 2.77e-11 Blood protein levels; TGCT cis rs6430585 0.583 rs60253740 chr2:136571852 G/T cg07169764 chr2:136633963 MCM6 1.18 10.93 0.7 6.96e-20 Corneal structure; TGCT cis rs11190604 1.000 rs9420797 chr10:102331147 C/T cg16342193 chr10:102329863 NA -0.41 -5.21 -0.42 7.71e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs35883536 0.647 rs10875314 chr1:101043207 G/C cg10298815 chr1:101004474 GPR88 -0.25 -4.73 -0.39 6.03e-6 Monocyte count; TGCT cis rs4906332 1.000 rs911549 chr14:103984537 T/C cg26031613 chr14:104095156 KLC1 0.6 5.33 0.43 4.56e-7 Coronary artery disease; TGCT cis rs986417 0.540 rs10144415 chr14:61112667 G/C cg18240143 chr14:60952599 C14orf39 0.93 4.64 0.38 8.58e-6 Gut microbiota (bacterial taxa); TGCT cis rs68170813 0.559 rs6963917 chr7:106953427 T/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs2180341 0.576 rs2057224 chr6:127624414 C/G cg24812749 chr6:127587940 RNF146 0.63 5.33 0.43 4.51e-7 Breast cancer; TGCT cis rs7432375 0.609 rs835637 chr3:136673157 A/T cg15507776 chr3:136538369 TMEM22 0.5 5.1 0.42 1.24e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs910316 0.836 rs6574212 chr14:75671659 G/A cg08847533 chr14:75593920 NEK9 -0.87 -9.53 -0.65 1.7e-16 Height; TGCT cis rs10256972 0.758 rs11979275 chr7:1069335 A/T cg03188948 chr7:1209495 NA 0.45 5.85 0.47 4.04e-8 Longevity;Endometriosis; TGCT cis rs13394619 0.935 rs6746291 chr2:11728381 T/C cg07314298 chr2:11723111 GREB1 -0.3 -5.39 -0.44 3.45e-7 Endometriosis; TGCT cis rs9486719 0.656 rs4839826 chr6:96853616 A/G cg18709589 chr6:96969512 KIAA0776 -0.65 -4.81 -0.4 4.36e-6 Migraine;Coronary artery disease; TGCT cis rs12210905 0.614 rs72845006 chr6:27492958 G/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs4654899 0.680 rs3125160 chr1:21127803 G/C cg01072550 chr1:21505969 NA 0.55 8.83 0.62 8.24e-15 Superior frontal gyrus grey matter volume; TGCT cis rs2243480 1.000 rs4718316 chr7:65648731 A/G cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs6089584 0.528 rs4925334 chr20:60626769 C/T cg06108461 chr20:60628389 TAF4 -0.43 -5.2 -0.42 7.98e-7 Body mass index; TGCT cis rs35306767 0.953 rs10904581 chr10:964685 A/T cg18964960 chr10:1102726 WDR37 0.57 4.55 0.38 1.27e-5 Eosinophil percentage of granulocytes; TGCT cis rs7611238 0.560 rs12054333 chr3:195032122 G/A cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.93e-6 Body mass index; TGCT cis rs17068510 0.572 rs66819405 chr8:3882298 C/T cg25338036 chr8:3047536 CSMD1 -0.46 -4.87 -0.4 3.28e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs4665630 0.614 rs2712105 chr2:23901353 A/G cg08063864 chr2:24346004 PFN4;LOC375190 -1.13 -5.4 -0.44 3.29e-7 Hypertension; TGCT cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs11118844 0.744 rs6655994 chr1:221933888 A/G cg04222084 chr1:221915650 DUSP10 -0.81 -5.34 -0.43 4.19e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs10193935 0.901 rs62142599 chr2:42548935 G/A cg27598129 chr2:42591480 NA -0.39 -5.45 -0.44 2.59e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.623 rs9893690 chr17:17753846 A/T cg04398451 chr17:18023971 MYO15A 0.31 4.68 0.39 7.4e-6 Total body bone mineral density; TGCT cis rs11098499 0.645 rs78422072 chr4:120281042 C/T cg09307838 chr4:120376055 NA 0.56 5.41 0.44 3.18e-7 Corneal astigmatism; TGCT cis rs478304 0.654 rs7947604 chr11:65442059 G/C cg27068330 chr11:65405492 SIPA1 -1.01 -11.26 -0.71 1.09e-20 Acne (severe); TGCT cis rs4455778 0.659 rs11185620 chr7:49025869 C/A cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs9430161 0.579 rs10864486 chr1:11040979 A/G cg27631724 chr1:11040367 C1orf127 0.55 6.46 0.5 2.16e-9 Ewing sarcoma; TGCT cis rs7647973 0.961 rs4955430 chr3:49378088 G/A cg05785598 chr3:49045655 WDR6 0.39 4.62 0.38 9.58e-6 Menarche (age at onset); TGCT cis rs7394190 0.748 rs2075641 chr10:75562108 G/A cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs6582630 0.537 rs7310749 chr12:38400472 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.39 0.55 1.92e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs2455799 0.553 rs12495958 chr3:15941439 G/T cg16303742 chr3:15540471 COLQ -0.24 -4.53 -0.38 1.36e-5 Mean platelet volume; TGCT cis rs514406 0.895 rs1925673 chr1:53326984 T/G cg24675658 chr1:53192096 ZYG11B -0.7 -7.91 -0.58 1.22e-12 Monocyte count; TGCT trans rs13064411 0.542 rs2399477 chr3:113222998 A/G cg00307254 chr3:126706825 PLXNA1 0.34 6.78 0.52 4.36e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs727563 0.569 rs73178647 chr22:41964168 G/A cg17554472 chr22:41940697 POLR3H -0.51 -5.26 -0.43 6.08e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs1385374 0.841 rs11059929 chr12:129296893 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.48 -0.37 1.67e-5 Systemic lupus erythematosus; TGCT cis rs7267979 1.000 rs6050559 chr20:25329915 A/G cg03522245 chr20:25566470 NINL 0.63 6.79 0.52 4.05e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs941408 1.000 rs1640273 chr19:2803227 C/T cg22153745 chr1:153894579 GATAD2B -0.62 -6.69 -0.51 6.82e-10 Total cholesterol levels; TGCT cis rs12220898 0.749 rs11101076 chr10:50486539 G/A cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs6967414 0.579 rs11980762 chr7:6756878 G/A cg00387323 chr7:6746715 ZNF12 0.76 4.65 0.39 8.23e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs8077889 0.672 rs2106764 chr17:41852717 T/A cg26893861 chr17:41843967 DUSP3 1.14 20.46 0.88 1.46e-41 Triglycerides; TGCT cis rs7824557 0.628 rs7005469 chr8:11194457 G/A cg21775007 chr8:11205619 TDH 0.7 6.86 0.52 2.93e-10 Retinal vascular caliber; TGCT cis rs2948294 0.545 rs11776397 chr8:8115161 C/T cg06636001 chr8:8085503 FLJ10661 0.82 7.16 0.54 6.3e-11 Red cell distribution width; TGCT cis rs6987853 0.933 rs55881007 chr8:42367290 A/G cg20539142 chr8:42623718 CHRNA6 0.19 4.46 0.37 1.83e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg00149659 chr3:10157352 C3orf10 -0.97 -6.25 -0.49 5.95e-9 Alzheimer's disease; TGCT cis rs7226408 0.948 rs72883571 chr18:34382245 T/G cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs6964587 0.758 rs35963176 chr7:91617115 C/T cg17063962 chr7:91808500 NA 0.76 6.18 0.49 8.37e-9 Breast cancer; TGCT cis rs2576037 0.583 rs541634 chr18:44420271 C/G cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.61 -0.38 9.88e-6 Personality dimensions; TGCT cis rs1005277 0.579 rs2505240 chr10:38442419 G/T cg13531842 chr10:38383804 ZNF37A -0.39 -4.64 -0.38 8.78e-6 Extrinsic epigenetic age acceleration; TGCT cis rs832540 0.902 rs194059 chr5:56197416 G/A cg12311346 chr5:56204834 C5orf35 -0.49 -5.16 -0.42 9.56e-7 Coronary artery disease; TGCT cis rs568617 0.767 rs2231884 chr11:65656564 C/T cg04055107 chr11:65626734 MUS81;CFL1 0.69 5.96 0.47 2.45e-8 Crohn's disease; TGCT cis rs17270561 0.723 rs12213243 chr6:25890108 C/T cg17042849 chr6:26104293 HIST1H4C -0.76 -5.36 -0.43 3.98e-7 Iron status biomarkers; TGCT cis rs7027203 0.595 rs4308796 chr9:96570165 G/A cg14396892 chr9:96623032 NA 0.23 4.58 0.38 1.13e-5 DNA methylation (variation); TGCT cis rs9308731 0.623 rs2241842 chr2:111879415 A/G cg04202892 chr2:111875749 ACOXL 0.54 6.25 0.49 6.18e-9 Chronic lymphocytic leukemia; TGCT cis rs1990950 0.716 rs6868374 chr5:156832202 G/A cg25387487 chr5:157003181 ADAM19 0.32 4.94 0.41 2.46e-6 Lung function (FEV1/FVC); TGCT cis rs736408 0.648 rs3774355 chr3:52817778 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.57 5.32 0.43 4.73e-7 Bipolar disorder; TGCT cis rs4689388 0.856 rs3200 chr4:6304878 C/T cg14416269 chr4:6271139 WFS1 0.41 5.5 0.44 2.08e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs12893668 0.514 rs3212090 chr14:104168863 C/T cg26031613 chr14:104095156 KLC1 -0.59 -5.0 -0.41 1.94e-6 Reticulocyte count; TGCT cis rs9527 0.615 rs7096452 chr10:104736563 G/A cg15744005 chr10:104629667 AS3MT -0.44 -5.19 -0.42 8.3e-7 Arsenic metabolism; TGCT cis rs7949030 0.725 rs12808829 chr11:62378660 G/A cg22862634 chr11:62369728 EML3;MTA2 0.7 8.79 0.62 1.02e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4074961 0.505 rs4653306 chr1:38065390 C/T cg11397548 chr1:38022522 DNALI1 0.41 4.67 0.39 7.69e-6 Axial length; TGCT cis rs2066819 0.892 rs2066807 chr12:56740682 C/G cg26714650 chr12:56694279 CS -1.36 -5.95 -0.47 2.56e-8 Psoriasis vulgaris; TGCT cis rs6951245 1.000 rs74369356 chr7:1071711 T/C cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12142240 0.583 rs5013330 chr1:46815154 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6570726 0.846 rs870491 chr6:145933390 T/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.49 -0.37 1.59e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4862750 0.872 rs9998172 chr4:187898773 T/C cg10295955 chr4:187884368 NA -1.02 -15.84 -0.82 1.42e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs6854703 chr4:98977586 A/T cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9467773 0.620 rs2504592 chr6:26640951 C/G cg09904177 chr6:26538194 HMGN4 0.68 6.36 0.5 3.55e-9 Intelligence (multi-trait analysis); TGCT cis rs2180341 0.960 rs9398842 chr6:127674662 T/C cg24812749 chr6:127587940 RNF146 0.93 7.4 0.55 1.83e-11 Breast cancer; TGCT cis rs1334894 1.000 rs72913405 chr6:35530062 C/T cg24281267 chr6:35479648 TULP1 -0.43 -4.47 -0.37 1.78e-5 Coronary artery disease; TGCT cis rs9303401 0.614 rs3887355 chr17:56538639 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.61 6.17 0.48 8.95e-9 Cognitive test performance; TGCT cis rs1008375 0.574 rs7670135 chr4:17566221 G/T cg18681998 chr4:17616180 MED28 0.75 7.15 0.54 6.68e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6032067 0.636 rs7272597 chr20:43908869 T/C cg16667508 chr20:43936853 MATN4;RBPJL -0.47 -7.24 -0.54 4.21e-11 Blood protein levels; TGCT cis rs6998277 0.830 rs12543046 chr8:103603809 A/G cg10187029 chr8:103597600 NA -0.55 -8.75 -0.62 1.31e-14 Migraine; TGCT trans rs1814175 0.791 rs1722023 chr11:49908136 G/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs2658782 0.901 rs11604909 chr11:93218355 C/G cg26827247 chr11:93063208 CCDC67 -0.56 -4.51 -0.38 1.51e-5 Pulmonary function decline; TGCT cis rs7142881 0.756 rs4981135 chr14:32332071 C/T cg19615721 chr14:32671389 NA 0.51 4.46 0.37 1.85e-5 Response to iloperidone treatment (QT prolongation); TGCT cis rs9952991 0.941 rs8096138 chr18:12808140 C/G cg23598886 chr18:12777645 NA -0.62 -5.57 -0.45 1.5e-7 Inflammatory skin disease; TGCT cis rs7010267 0.902 rs10505348 chr8:119972696 A/G cg17171407 chr8:119960777 TNFRSF11B 0.33 6.18 0.49 8.48e-9 Total body bone mineral density (age 45-60); TGCT cis rs1799949 0.965 rs4792989 chr17:41437552 T/C cg05368731 chr17:41323189 NBR1 1.11 11.95 0.73 2.23e-22 Menopause (age at onset); TGCT cis rs35417517 1 rs35417517 chr7:91772730 CG/C cg17063962 chr7:91808500 NA 0.93 10.08 0.67 8.03e-18 Breast cancer; TGCT cis rs13188771 0.578 rs17137390 chr5:100918526 C/T cg05545777 chr5:101119128 NA 0.5 4.47 0.37 1.76e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7937682 0.889 rs541198 chr11:111475340 A/G cg09085632 chr11:111637200 PPP2R1B -1.06 -11.27 -0.71 1.04e-20 Primary sclerosing cholangitis; TGCT cis rs9633740 0.578 rs11185951 chr10:82301536 G/C cg01528321 chr10:82214614 TSPAN14 -0.87 -5.57 -0.45 1.51e-7 Post bronchodilator FEV1; TGCT cis rs7113874 0.569 rs10769915 chr11:8597449 C/G cg14521421 chr11:8862019 ST5 0.28 4.44 0.37 1.96e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs909674 0.775 rs8138462 chr22:39839670 G/C cg02038168 chr22:39784481 NA -0.71 -5.56 -0.45 1.55e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT trans rs10506458 0.834 rs55966529 chr12:63384114 A/C cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.46 -7.24 -0.55 4.04e-11 Hemostatic factors and hematological phenotypes; TGCT cis rs807669 0.807 rs712948 chr22:19206499 A/G cg02655711 chr22:19163373 SLC25A1 0.41 9.45 0.65 2.75e-16 Metabolite levels; TGCT cis rs13256369 0.802 rs12541520 chr8:8564146 G/T cg06671706 chr8:8559999 CLDN23 0.34 4.53 0.38 1.38e-5 Obesity-related traits; TGCT cis rs8072100 0.875 rs62073966 chr17:45600013 T/A cg08085267 chr17:45401833 C17orf57 0.48 5.31 0.43 4.86e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs3862030 0.503 rs6584506 chr10:104254428 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs9303542 0.625 rs8064626 chr17:46567851 G/A cg25032089 chr17:46643351 HOXB3 0.57 5.75 0.46 6.47e-8 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7772486 0.875 rs2777476 chr6:146345024 A/G cg05347473 chr6:146136440 FBXO30 0.53 4.98 0.41 2.11e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs694739 0.894 rs887314 chr11:64053157 T/G cg23796481 chr11:64053134 BAD;GPR137 0.66 6.88 0.53 2.67e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs6725041 0.819 rs1521644 chr2:213091246 A/G cg16329650 chr2:213403929 ERBB4 -0.53 -4.58 -0.38 1.12e-5 QT interval (ambient particulate matter interaction); TGCT cis rs6951245 1.000 rs11770909 chr7:1086716 G/A cg18402987 chr7:1209562 NA 0.74 6.19 0.49 7.92e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.68e-9 Blood metabolite levels; TGCT cis rs9581857 0.547 rs9579087 chr13:28059780 G/A cg22138327 chr13:27999177 GTF3A 0.73 4.55 0.38 1.25e-5 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs10504229 1.000 rs61733801 chr8:58192513 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs12510870 0.599 rs7667019 chr4:74453035 C/T cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs8016982 0.633 rs8015423 chr14:81719357 C/T cg01989461 chr14:81687754 GTF2A1 0.76 7.5 0.56 1.08e-11 Schizophrenia; TGCT cis rs13082711 0.554 rs1494422 chr3:27375190 T/C cg02860705 chr3:27208620 NA -0.36 -5.39 -0.44 3.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs1215050 0.904 rs2903153 chr4:99057457 C/T cg05340658 chr4:99064831 C4orf37 0.42 5.03 0.41 1.65e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs11170631 0.504 rs10128880 chr12:53927783 T/C cg16917193 chr12:54089295 NA 1.02 10.39 0.68 1.44e-18 Height; TGCT cis rs6693567 0.545 rs1260385 chr1:150316385 G/A cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs11098499 0.954 rs12505469 chr4:120249585 C/T cg09307838 chr4:120376055 NA 0.63 5.89 0.47 3.41e-8 Corneal astigmatism; TGCT cis rs2204008 0.658 rs12371956 chr12:38298010 A/T cg26384229 chr12:38710491 ALG10B 0.8 7.04 0.53 1.17e-10 Bladder cancer; TGCT cis rs2201728 1.000 rs2201728 chr4:100163873 G/A cg07219303 chr4:100140905 ADH6 -0.35 -5.2 -0.42 8.15e-7 Cardiac Troponin-T levels; TGCT cis rs611744 0.967 rs613644 chr8:109188994 G/A cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs148803332 1 rs148803332 chr17:65958250 CAAAAGAAA/C cg12091567 chr17:66097778 LOC651250 0.88 6.66 0.51 7.92e-10 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes; TGCT cis rs3780378 0.875 rs7032785 chr9:5042046 C/T cg02405213 chr9:5042618 JAK2 -0.59 -7.69 -0.57 3.87e-12 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs6951245 0.882 rs10252404 chr7:1209607 C/A cg00738919 chr7:1100172 C7orf50 0.47 4.53 0.38 1.37e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2299587 0.554 rs3913558 chr8:17747909 T/G cg04898035 chr8:17640624 MTUS1 -0.21 -4.7 -0.39 6.92e-6 Economic and political preferences; TGCT cis rs250677 0.522 rs2895837 chr5:148357535 C/T cg18129178 chr5:148520854 ABLIM3 0.35 4.58 0.38 1.12e-5 Breast cancer; TGCT cis rs10751667 0.961 rs6597953 chr11:991099 G/A cg06064525 chr11:970664 AP2A2 -0.3 -6.06 -0.48 1.51e-8 Alzheimer's disease (late onset); TGCT cis rs12549902 0.897 rs12549294 chr8:41506380 A/G cg21772509 chr8:41503840 NKX6-3 0.89 10.58 0.69 4.81e-19 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index;Insulin levels adjusted for BMI;Type 2 diabetes; TGCT cis rs6901250 0.851 rs339362 chr6:117165370 A/C cg12892004 chr6:117198278 RFX6 -0.55 -6.76 -0.52 4.74e-10 C-reactive protein levels; TGCT cis rs875971 0.964 rs2277911 chr7:65958625 T/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs7584330 0.736 rs6431541 chr2:238376190 A/T cg14458575 chr2:238380390 NA 0.49 7.83 0.58 1.89e-12 Prostate cancer; TGCT cis rs6089584 0.927 rs2281734 chr20:60582401 C/A cg13665807 chr20:60559372 TAF4 -0.42 -4.52 -0.38 1.43e-5 Body mass index; TGCT cis rs11209185 0.509 rs9436790 chr1:68447044 G/A cg22082780 chr1:68452167 NA 0.31 4.7 0.39 6.73e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs9296661 0.522 rs1326570 chr6:51665597 C/T cg20180370 chr6:50691003 TFAP2D 0.46 4.55 0.38 1.27e-5 Weight loss (gastric bypass surgery); TGCT cis rs1198430 0.925 rs1767148 chr1:23765472 A/G cg19827787 chr1:23763612 ASAP3 0.44 4.71 0.39 6.55e-6 Total cholesterol levels; TGCT cis rs6598955 0.671 rs12139514 chr1:26575939 G/A cg04990556 chr1:26633338 UBXN11 0.62 4.73 0.39 6.12e-6 Obesity-related traits; TGCT cis rs60843830 1.000 rs58461606 chr2:267367 G/T cg25945732 chr2:264204 ACP1;SH3YL1 0.72 7.19 0.54 5.25e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs17376456 0.825 rs10052662 chr5:93271385 A/G cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs10927875 0.632 rs2013745 chr1:16126676 G/A cg21385522 chr1:16154831 NA -0.96 -15.34 -0.81 1.96e-30 Dilated cardiomyopathy; TGCT cis rs1055129 0.655 rs7223416 chr17:73836162 C/G cg08125733 chr17:73851984 WBP2 0.56 5.09 0.42 1.28e-6 White matter hyperintensity burden; TGCT cis rs7017914 0.967 rs3098867 chr8:71916871 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.57 -5.31 -0.43 4.8e-7 Bone mineral density; TGCT cis rs1862618 0.853 rs832551 chr5:56180112 T/G cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT cis rs2535633 0.588 rs2564930 chr3:53017307 T/C cg11645453 chr3:52864694 ITIH4 -0.27 -4.96 -0.41 2.25e-6 Body mass index; TGCT cis rs7017914 0.967 rs35295900 chr8:71642061 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs2485376 1.000 rs3781295 chr10:104140602 G/A cg26089160 chr10:104170217 PSD 0.48 4.52 0.38 1.44e-5 QT interval; TGCT cis rs12134133 1.000 rs11584921 chr1:207441975 A/G cg02152968 chr1:207494213 CD55 0.62 4.67 0.39 7.71e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs9611565 0.659 rs9611604 chr22:41916001 C/G cg06481639 chr22:41940642 POLR3H -0.73 -6.64 -0.51 8.91e-10 Vitiligo; TGCT cis rs2204008 0.806 rs3922574 chr12:38329069 C/T cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Bladder cancer; TGCT cis rs2153535 0.547 rs9502720 chr6:8541362 C/A cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.46e-7 Motion sickness; TGCT cis rs2458413 0.669 rs12681140 chr8:105346112 A/C cg23108931 chr8:105342351 NA 0.35 6.24 0.49 6.25e-9 Paget's disease; TGCT cis rs4665809 0.590 rs962217 chr2:26438276 T/C cg26119090 chr2:26468346 HADHA;HADHB -1.0 -7.42 -0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs910316 1.000 rs10140851 chr14:75512612 G/A cg08847533 chr14:75593920 NEK9 0.96 10.6 0.69 4.36e-19 Height; TGCT cis rs12220898 0.749 rs2377975 chr10:50481421 A/G cg06072769 chr10:50146962 WDFY4 0.38 4.98 0.41 2.07e-6 Inflammatory biomarkers; TGCT cis rs28595532 0.920 rs112097820 chr4:119746532 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs896854 0.625 rs4735335 chr8:95973327 G/C cg16049864 chr8:95962084 TP53INP1 -0.75 -10.48 -0.69 8.55e-19 Type 2 diabetes; TGCT cis rs3820068 0.581 rs72645864 chr1:15921153 C/T cg05660106 chr1:15850417 CASP9 0.84 8.27 0.6 1.8e-13 Systolic blood pressure; TGCT cis rs1580019 0.510 rs4723162 chr7:32543804 C/A cg07520158 chr7:32535189 LSM5;AVL9 0.58 4.96 0.41 2.28e-6 Cognitive ability; TGCT cis rs13191362 1.000 rs34619021 chr6:163029767 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.18e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs17125944 0.505 rs3783447 chr14:53191647 G/A cg00686598 chr14:53173677 PSMC6 1.19 6.34 0.49 3.96e-9 Alzheimer's disease (late onset); TGCT cis rs10479542 0.929 rs10074573 chr5:178976966 C/T cg09060608 chr5:178986726 RUFY1 -0.49 -5.53 -0.44 1.83e-7 Lung cancer; TGCT cis rs10782582 0.609 rs1770889 chr1:76401166 A/G cg22875332 chr1:76189707 ACADM -0.45 -4.53 -0.38 1.34e-5 Daytime sleep phenotypes; TGCT cis rs61990749 0.597 rs176971 chr14:78191599 T/G cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs2933343 0.729 rs1680794 chr3:128620390 A/G cg11901034 chr3:128598214 ACAD9 -0.63 -6.06 -0.48 1.54e-8 IgG glycosylation; TGCT cis rs11098499 0.955 rs11931312 chr4:120159023 T/C cg24670566 chr4:120433619 PDE5A 0.23 4.45 0.37 1.89e-5 Corneal astigmatism; TGCT cis rs4372836 1.000 rs11127188 chr2:28972852 G/A cg09522027 chr2:28974177 PPP1CB -0.58 -5.07 -0.41 1.42e-6 Body mass index; TGCT cis rs12989701 0.877 rs13029812 chr2:127872622 A/G cg08168897 chr2:127865431 BIN1 0.5 5.34 0.43 4.28e-7 Alzheimer's disease (late onset); TGCT cis rs10782582 0.609 rs111914775 chr1:76319036 C/T cg10523679 chr1:76189770 ACADM -0.59 -5.42 -0.44 2.94e-7 Daytime sleep phenotypes; TGCT cis rs17401966 1.000 rs11578788 chr1:10422958 A/G cg19773385 chr1:10388646 KIF1B -0.21 -4.5 -0.37 1.57e-5 Hepatocellular carcinoma; TGCT cis rs1372520 0.684 rs2737010 chr4:90746466 G/A cg01966878 chr4:90757139 SNCA -0.3 -4.76 -0.39 5.2e-6 Neuroticism; TGCT trans rs9295123 0.898 rs1382785 chr6:160573407 C/T cg22927510 chr22:50968328 TYMP -0.51 -6.82 -0.52 3.63e-10 Blood protein levels; TGCT cis rs9486719 0.948 rs6920913 chr6:96874297 A/G cg06623918 chr6:96969491 KIAA0776 0.98 9.49 0.65 2.2e-16 Migraine;Coronary artery disease; TGCT cis rs34734847 0.965 rs2005455 chr12:121128699 A/G cg21892295 chr12:121157589 UNC119B -0.23 -5.49 -0.44 2.13e-7 Mean corpuscular volume; TGCT cis rs1005277 0.579 rs2474594 chr10:38426661 G/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1552244 0.938 rs34750074 chr3:10091740 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -6.01 -0.47 1.91e-8 Alzheimer's disease; TGCT cis rs1975974 0.935 rs67979358 chr17:21723834 G/C cg18423549 chr17:21743878 NA -0.49 -4.76 -0.39 5.3e-6 Psoriasis; TGCT cis rs8103278 0.860 rs11669073 chr19:46324880 C/T cg14061069 chr19:46274453 DMPK -0.44 -6.14 -0.48 1.04e-8 Coronary artery disease; TGCT trans rs1499614 0.901 rs3936 chr7:66126489 C/T cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs55692411 0.537 rs7648652 chr3:50135412 A/C cg14019146 chr3:50243930 SLC38A3 -0.22 -4.6 -0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT cis rs6901004 0.803 rs1022092 chr6:111427286 G/A cg15721981 chr6:111408429 SLC16A10 -0.52 -4.53 -0.38 1.35e-5 Blood metabolite levels; TGCT cis rs7201929 1.000 rs8061877 chr16:28856819 C/T cg09754948 chr16:28834200 ATXN2L -0.61 -4.76 -0.39 5.21e-6 QT interval; TGCT cis rs3091242 0.967 rs3091240 chr1:25676935 G/T cg10117171 chr1:25599238 RHD -0.36 -5.85 -0.46 4.18e-8 Erythrocyte sedimentation rate; TGCT cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2795502 0.938 rs2744085 chr10:43341976 C/T cg20628663 chr10:43360327 NA 0.45 6.42 0.5 2.61e-9 Blood protein levels; TGCT cis rs4622507 0.773 rs36054803 chr16:55054817 C/T cg04853843 chr16:55358461 IRX6 -0.54 -4.97 -0.41 2.22e-6 Social communication problems; TGCT cis rs9638182 0.667 rs13240065 chr7:73015369 G/A cg14087351 chr7:73037990 MLXIPL -0.68 -5.21 -0.42 7.48e-7 Triglycerides; TGCT cis rs7829975 0.606 rs7819827 chr8:8797055 G/C cg15556689 chr8:8085844 FLJ10661 -0.69 -6.14 -0.48 1.01e-8 Mood instability; TGCT cis rs7666738 0.753 rs2903143 chr4:99040480 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7611238 0.583 rs4677844 chr3:195155338 C/G cg27323046 chr3:195102265 ACAP2 0.33 4.44 0.37 1.96e-5 Body mass index; TGCT cis rs11203032 0.831 rs11203009 chr10:90927163 G/A cg16672925 chr10:90967113 CH25H 0.73 4.5 0.37 1.55e-5 Heart failure; TGCT cis rs2657888 1.000 rs7310284 chr12:56935652 A/G cg23932658 chr12:57637574 STAC3 0.54 5.03 0.41 1.67e-6 Adiponectin levels; TGCT cis rs7772486 0.597 rs2246132 chr6:146182515 C/G cg13319975 chr6:146136371 FBXO30 -0.68 -6.24 -0.49 6.44e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs12579753 0.810 rs1343934 chr12:82123112 G/A cg07988820 chr12:82153109 PPFIA2 -0.68 -7.49 -0.56 1.1e-11 Resting heart rate; TGCT cis rs17068510 0.572 rs67885938 chr8:3877995 G/C cg25338036 chr8:3047536 CSMD1 -0.46 -4.87 -0.4 3.28e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs651907 0.535 rs35810977 chr3:101531380 G/A cg12386194 chr3:101231763 SENP7 0.46 4.52 0.38 1.43e-5 Colorectal cancer; TGCT cis rs2836974 0.563 rs997147 chr21:40695325 A/G cg06238570 chr21:40685208 BRWD1 -0.8 -8.38 -0.6 9.46e-14 Cognitive function; TGCT cis rs644799 0.710 rs519511 chr11:95538270 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.5 0.61 5.03e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7020830 0.825 rs66684257 chr9:37199087 G/T cg14294708 chr9:37120828 ZCCHC7 1.17 16.59 0.83 2.84e-33 Schizophrenia; TGCT cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg13770153 chr20:60521292 NA -0.62 -7.76 -0.57 2.73e-12 Body mass index; TGCT cis rs7833790 0.724 rs6473311 chr8:82726682 G/A cg17211192 chr8:82754475 SNX16 -0.95 -8.83 -0.62 8.45e-15 Diastolic blood pressure; TGCT cis rs826838 0.967 rs1352123 chr12:39130992 T/C cg26384229 chr12:38710491 ALG10B -0.86 -7.7 -0.57 3.65e-12 Heart rate; TGCT cis rs4888262 0.545 rs8052923 chr16:74680105 C/T cg01733217 chr16:74700730 RFWD3 0.76 7.58 0.56 7.1e-12 Testicular germ cell tumor; TGCT cis rs7681440 0.904 rs7672979 chr4:90767873 A/G cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs7429990 0.901 rs9825114 chr3:48138082 A/G cg11946769 chr3:48343235 NME6 -0.56 -4.52 -0.38 1.42e-5 Educational attainment (years of education); TGCT cis rs7949030 0.626 rs7124057 chr11:62334096 A/G cg22862634 chr11:62369728 EML3;MTA2 0.71 9.07 0.63 2.23e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1050631 1.000 rs1789514 chr18:33692654 T/C cg25426722 chr18:33708991 SLC39A6;ELP2 0.51 4.99 0.41 2.03e-6 Esophageal squamous cell cancer (length of survival); TGCT cis rs9473924 0.580 rs68118663 chr6:50815367 C/T cg14470998 chr6:50812995 TFAP2B 1.35 8.5 0.61 5.05e-14 Body mass index; TGCT cis rs2072499 0.898 rs2758609 chr1:156202868 G/A cg24450063 chr1:156163899 SLC25A44 1.05 11.04 0.7 3.74e-20 Testicular germ cell tumor; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg26338869 chr17:61819248 STRADA -0.52 -4.85 -0.4 3.6e-6 Prudent dietary pattern; TGCT cis rs10197940 0.648 rs7587301 chr2:152347600 A/G cg19508488 chr2:152266495 RIF1 0.59 4.99 0.41 2.03e-6 Lung cancer; TGCT cis rs9814567 0.964 rs9815894 chr3:134282796 C/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.18 -0.64 1.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs3733585 0.638 rs6449155 chr4:9956547 T/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs9303401 0.592 rs12936771 chr17:56725052 T/C cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs713587 0.520 rs530951 chr2:25307005 C/T cg01884057 chr2:25150051 NA -0.26 -4.87 -0.4 3.36e-6 Body mass index in non-asthmatics; TGCT cis rs7172809 0.573 rs59831220 chr15:77455246 A/G cg22256960 chr15:77711686 NA -0.48 -4.63 -0.38 9.17e-6 Glucose homeostasis traits; TGCT cis rs344364 0.511 rs2982449 chr16:1947878 C/G cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs854765 0.583 rs6502619 chr17:17779704 C/G cg09796270 chr17:17721594 SREBF1 -0.27 -5.5 -0.44 2.04e-7 Total body bone mineral density; TGCT cis rs10504229 0.954 rs903717 chr8:58167856 A/G cg22535103 chr8:58192502 C8orf71 -0.35 -4.69 -0.39 7.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs769267 0.930 rs892022 chr19:19613381 G/A cg08509172 chr19:19383838 TM6SF2 -0.34 -4.52 -0.38 1.4e-5 Tonsillectomy; TGCT cis rs7568458 0.846 rs6743030 chr2:85763520 C/T cg17127132 chr2:85788382 GGCX 0.63 5.94 0.47 2.65e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9467711 0.606 rs9379900 chr6:26603811 A/C cg16898833 chr6:26189333 HIST1H4D 1.02 5.25 0.43 6.32e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9549367 0.713 rs9549356 chr13:113851633 A/G cg09473364 chr13:112927190 NA -0.3 -4.6 -0.38 1.01e-5 Platelet distribution width; TGCT cis rs35883536 0.647 rs10875316 chr1:101044150 G/A cg06223162 chr1:101003688 GPR88 -0.41 -7.55 -0.56 7.99e-12 Monocyte count; TGCT cis rs896854 0.540 rs2011567 chr8:95971920 G/A cg23172400 chr8:95962367 TP53INP1 -0.39 -6.53 -0.51 1.52e-9 Type 2 diabetes; TGCT cis rs736408 0.677 rs678 chr3:52820981 A/T cg07507251 chr3:52567010 NT5DC2 0.48 6.76 0.52 4.7e-10 Bipolar disorder; TGCT cis rs1055129 0.537 rs1135640 chr17:73949540 C/G cg08125733 chr17:73851984 WBP2 -0.55 -5.23 -0.43 6.94e-7 White matter hyperintensity burden; TGCT cis rs763121 0.889 rs4820335 chr22:38935927 C/G cg06022373 chr22:39101656 GTPBP1 -0.7 -6.82 -0.52 3.58e-10 Menopause (age at onset); TGCT cis rs9486719 0.857 rs3798293 chr6:97033370 A/G cg06623918 chr6:96969491 KIAA0776 -1.03 -9.64 -0.65 9.66e-17 Migraine;Coronary artery disease; TGCT cis rs9811920 0.535 rs792835 chr3:99476295 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.39 4.6 0.38 1.04e-5 Axial length; TGCT cis rs2932538 0.961 rs10745332 chr1:113189053 G/A cg22162597 chr1:113214053 CAPZA1 -0.27 -5.98 -0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs1997103 1.000 rs1997098 chr7:55405594 G/T cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs11249608 0.548 rs6601007 chr5:178455796 G/C cg01312482 chr5:178451176 ZNF879 -0.48 -4.77 -0.39 5.15e-6 Pubertal anthropometrics; TGCT cis rs854765 0.583 rs8065563 chr17:17782404 A/G cg09796270 chr17:17721594 SREBF1 0.28 5.61 0.45 1.28e-7 Total body bone mineral density; TGCT cis rs12681287 0.547 rs7459877 chr8:87505660 G/A cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs6728642 1.000 rs60608738 chr2:97608085 G/A cg26665480 chr2:98280029 ACTR1B -0.91 -5.37 -0.43 3.77e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs13191362 1.000 rs35126854 chr6:163012443 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs28386778 0.897 rs896064 chr17:61860932 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs9910055 0.615 rs189049 chr17:42197213 A/C cg13607699 chr17:42295918 UBTF -0.55 -5.1 -0.42 1.24e-6 Total body bone mineral density; TGCT cis rs8077577 0.945 rs62073649 chr17:18080522 T/C cg09161412 chr17:18057145 MYO15A -0.66 -5.36 -0.43 3.94e-7 Obesity-related traits; TGCT cis rs11190604 0.767 rs11190520 chr10:102175309 T/C cg16342193 chr10:102329863 NA -0.4 -5.06 -0.41 1.5e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1799949 1.000 rs2271573 chr17:41327621 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.88 0.4 3.2e-6 Menopause (age at onset); TGCT cis rs9948 0.786 rs62156226 chr2:97417108 G/A cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT trans rs7613875 0.580 rs12634780 chr3:50043341 A/T cg21659725 chr3:3221576 CRBN -0.7 -7.76 -0.57 2.66e-12 Body mass index; TGCT cis rs2216164 1.000 rs2041864 chr12:68538489 C/T cg17065850 chr12:67807625 NA 0.23 4.44 0.37 1.93e-5 Alopecia areata; TGCT cis rs2204008 0.720 rs11181343 chr12:38323616 G/T cg13010199 chr12:38710504 ALG10B 0.59 4.59 0.38 1.07e-5 Bladder cancer; TGCT cis rs7119 0.717 rs62009069 chr15:77817877 T/G cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs1371867 0.817 rs7846076 chr8:101327629 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs3091242 0.866 rs11249249 chr1:25758134 A/G cg09222892 chr1:25734099 RHCE -0.42 -6.74 -0.52 5.38e-10 Erythrocyte sedimentation rate; TGCT cis rs2836974 0.897 rs8132295 chr21:40527774 A/G cg17971929 chr21:40555470 PSMG1 -0.98 -9.43 -0.65 3.07e-16 Cognitive function; TGCT cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs2456568 0.508 rs1607403 chr11:93660514 A/G cg17595323 chr11:93583763 C11orf90 -0.42 -5.26 -0.43 6.2e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs28374715 0.532 rs316606 chr15:41772202 A/C cg18705301 chr15:41695430 NDUFAF1 -0.93 -17.19 -0.84 1.29e-34 Ulcerative colitis; TGCT trans rs10809457 0.596 rs2015995 chr9:11559202 G/A cg07726222 chr16:2125875 TSC2 0.22 6.64 0.51 8.77e-10 Palmitic acid (16:0) levels; TGCT cis rs11650494 0.808 rs76366926 chr17:47396628 T/C cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs2070488 0.930 rs2370840 chr3:38529825 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.93 9.8 0.66 3.77e-17 Electrocardiographic conduction measures; TGCT cis rs4819052 0.765 rs2838827 chr21:46656146 C/T cg06618935 chr21:46677482 NA -0.36 -5.48 -0.44 2.23e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs5757676 0.858 rs6001585 chr22:39812986 G/T cg11247378 chr22:39784982 NA -0.71 -7.51 -0.56 1e-11 IgG glycosylation; TGCT cis rs7772486 0.754 rs9373476 chr6:146139741 C/G cg05347473 chr6:146136440 FBXO30 0.55 5.16 0.42 9.53e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1205863 1.000 rs1205872 chr6:11945143 T/C cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs873946 0.648 rs35417213 chr10:134553749 A/G cg18305652 chr10:134549665 INPP5A 0.35 5.72 0.46 7.3900000000000007e-08 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6988636 1.000 rs13260318 chr8:124190165 C/G cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs736408 0.609 rs2268025 chr3:52795224 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.9 -0.4 2.9e-6 Bipolar disorder; TGCT cis rs317865 0.609 rs73234660 chr4:16221047 G/C cg04764131 chr4:16228633 TAPT1;FLJ39653 0.78 5.15 0.42 1.01e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs3806843 0.576 rs246037 chr5:140331846 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs9308731 0.966 rs4849442 chr2:111934219 C/T cg04202892 chr2:111875749 ACOXL 0.44 4.75 0.39 5.45e-6 Chronic lymphocytic leukemia; TGCT cis rs3820068 0.603 rs17448778 chr1:15985306 A/G cg05660106 chr1:15850417 CASP9 0.8 8.04 0.59 5.97e-13 Systolic blood pressure; TGCT cis rs2228479 0.850 rs11645240 chr16:89837326 T/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs76419734 0.558 rs17035939 chr4:106526544 T/C cg24545054 chr4:106630052 GSTCD;INTS12 0.82 4.66 0.39 7.91e-6 Post bronchodilator FEV1; TGCT cis rs6728642 0.831 rs10496325 chr2:97683329 C/T cg26665480 chr2:98280029 ACTR1B 0.91 5.85 0.46 4.19e-8 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs7208859 0.623 rs56018041 chr17:29059985 G/A cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1153858 1.000 rs1153858 chr15:45652703 A/G cg26924012 chr15:45694286 SPATA5L1 -0.99 -11.84 -0.73 4.26e-22 Homoarginine levels; TGCT trans rs797680 0.856 rs693737 chr1:93724924 G/A cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7659604 0.605 rs1507994 chr4:122749541 C/T cg06713675 chr4:122721982 EXOSC9 -0.62 -8.45 -0.6 6.5e-14 Type 2 diabetes; TGCT cis rs12135062 0.851 rs2651926 chr1:3101820 C/T cg25382214 chr1:3105252 PRDM16 -0.3 -5.28 -0.43 5.56e-7 Migraine; TGCT cis rs9921338 0.887 rs6498183 chr16:11430908 C/T cg00044050 chr16:11439710 C16orf75 -0.88 -6.75 -0.52 5.08e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs4455778 0.500 rs10224270 chr7:49041354 T/C cg26309511 chr7:48887640 NA 0.51 6.66 0.51 7.85e-10 Lung cancer in never smokers; TGCT cis rs6582630 0.519 rs1851121 chr12:38389467 T/C cg26384229 chr12:38710491 ALG10B 0.83 7.26 0.55 3.72e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs2046867 0.908 rs62251649 chr3:72809610 A/C cg25664220 chr3:72788482 NA -0.52 -6.66 -0.51 8.07e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs7178572 0.568 rs12911371 chr15:77689050 C/T cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs12497850 0.931 rs13315711 chr3:48986399 A/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.41 -0.44 3.09e-7 Parkinson's disease; TGCT cis rs1372520 0.684 rs3113355 chr4:90745345 A/T cg20003494 chr4:90757398 SNCA -0.63 -5.06 -0.41 1.48e-6 Neuroticism; TGCT cis rs4665809 0.590 rs4665837 chr2:26434022 C/A cg22920501 chr2:26401640 FAM59B -0.8 -6.34 -0.5 3.8e-9 Gut microbiome composition (summer); TGCT cis rs6951245 1.000 rs76833820 chr7:1070278 A/T cg03188948 chr7:1209495 NA 0.59 4.82 0.4 4.06e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.64 7.0 0.53 1.43e-10 Blood metabolite levels; TGCT cis rs514406 0.861 rs7524476 chr1:53240212 C/T cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs595982 0.527 rs73061659 chr19:49373556 G/A cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.16 -0.64 1.35e-15 Red cell distribution width; TGCT cis rs2243480 1.000 rs35735127 chr7:65300423 G/T cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs10754283 0.935 rs1934046 chr1:90119290 A/T cg03145924 chr1:90228473 NA 0.4 4.52 0.38 1.4e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1153858 0.943 rs1145079 chr15:45681761 T/C cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs9633740 0.947 rs1878036 chr10:82280137 T/G cg01528321 chr10:82214614 TSPAN14 1.01 8.15 0.59 3.39e-13 Post bronchodilator FEV1; TGCT cis rs76473307 1.000 rs79375984 chr20:57399869 T/C cg06163629 chr20:57414884 GNASAS;GNAS -0.67 -4.58 -0.38 1.13e-5 Chronic lymphocytic leukemia; TGCT cis rs6460942 0.822 rs13340498 chr7:12233877 G/T cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs1552244 0.554 rs6762702 chr3:10055789 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs7659604 0.702 rs6815790 chr4:122695385 A/C cg06713675 chr4:122721982 EXOSC9 -0.56 -7.41 -0.55 1.72e-11 Type 2 diabetes; TGCT cis rs9549367 0.713 rs11620600 chr13:113829090 G/A cg18105134 chr13:113819100 PROZ -0.47 -8.24 -0.59 2.05e-13 Platelet distribution width; TGCT cis rs11745493 0.609 rs1392436 chr5:122835138 A/G cg15125798 chr5:122621645 NA -0.48 -4.5 -0.37 1.54e-5 Total body bone mineral density; TGCT cis rs12142240 0.698 rs68112720 chr1:46813888 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs651907 0.557 rs13099674 chr3:101489629 G/A cg11279151 chr3:101281821 RG9MTD1 -0.32 -6.66 -0.51 7.93e-10 Colorectal cancer; TGCT cis rs7618915 0.547 rs62255371 chr3:52747321 A/G cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs6951245 1.000 rs79765398 chr7:1073764 A/G cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1215050 0.765 rs181521 chr4:98745728 A/C cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs4332037 0.624 rs11764337 chr7:1892309 A/G cg25206134 chr2:45395956 NA -0.82 -7.28 -0.55 3.4e-11 Bipolar disorder; TGCT cis rs2204008 0.807 rs8186948 chr12:38325101 C/G cg26384229 chr12:38710491 ALG10B 0.79 6.98 0.53 1.61e-10 Bladder cancer; TGCT cis rs734999 0.588 rs745367 chr1:2524457 T/C cg18854424 chr1:2615690 NA 0.5 5.78 0.46 5.64e-8 Ulcerative colitis; TGCT cis rs55823223 0.503 rs9906971 chr17:73848477 A/G cg10935138 chr17:73851978 WBP2 0.82 7.59 0.56 6.81e-12 Psoriasis; TGCT cis rs1994135 0.549 rs2218650 chr12:33734783 A/G cg06521331 chr12:34319734 NA -0.34 -5.38 -0.43 3.62e-7 Resting heart rate; TGCT cis rs6831352 0.918 rs2602895 chr4:100045840 C/T cg12011299 chr4:100065546 ADH4 0.41 4.92 0.4 2.72e-6 Alcohol dependence; TGCT cis rs7267979 0.966 rs3827014 chr20:25371559 C/T cg16686733 chr20:25566563 NINL -0.59 -5.87 -0.47 3.75e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9926296 0.712 rs258330 chr16:89729574 T/G cg27121462 chr16:89883253 FANCA -0.54 -5.01 -0.41 1.83e-6 Vitiligo; TGCT cis rs2486288 0.656 rs11629859 chr15:45547121 T/G cg14582100 chr15:45693742 SPATA5L1 -0.44 -5.02 -0.41 1.78e-6 Glomerular filtration rate; TGCT cis rs1865760 0.532 rs2794719 chr6:26088890 T/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.82 7.71 0.57 3.6e-12 Height; TGCT cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs7772486 0.790 rs2265917 chr6:146212285 A/G cg23711669 chr6:146136114 FBXO30 0.89 10.16 0.67 5.28e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs9549367 0.762 rs9549694 chr13:113870510 G/A cg18105134 chr13:113819100 PROZ -0.36 -6.06 -0.48 1.51e-8 Platelet distribution width; TGCT cis rs7727544 0.716 rs4594848 chr5:131586598 C/A cg21474247 chr5:131268130 NA 0.32 4.71 0.39 6.41e-6 Blood metabolite levels; TGCT cis rs1865760 0.865 rs9467648 chr6:25957933 T/A cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.88e-6 Height; TGCT cis rs7829975 0.774 rs11775523 chr8:8679176 A/G cg08975724 chr8:8085496 FLJ10661 0.53 4.74 0.39 5.88e-6 Mood instability; TGCT cis rs10791323 0.604 rs2723598 chr11:133711652 G/A cg15485101 chr11:133734466 NA 0.39 5.12 0.42 1.15e-6 Childhood ear infection; TGCT cis rs6582630 0.519 rs8186881 chr12:38310285 A/G cg26384229 chr12:38710491 ALG10B 0.82 7.23 0.54 4.32e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs514406 0.584 rs7524702 chr1:53197830 G/A cg16325326 chr1:53192061 ZYG11B -0.89 -13.12 -0.76 3.38e-25 Monocyte count; TGCT cis rs7659604 0.539 rs7686084 chr4:122764725 A/C cg19748678 chr4:122722346 EXOSC9 0.89 8.94 0.63 4.53e-15 Type 2 diabetes; TGCT cis rs651907 0.557 rs1031710 chr3:101463895 C/T cg12386194 chr3:101231763 SENP7 0.48 4.63 0.38 9.23e-6 Colorectal cancer; TGCT cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs1691799 0.867 rs1039056 chr12:66760391 C/T cg16791601 chr12:66731901 HELB -0.28 -6.03 -0.48 1.74e-8 White blood cell count (basophil); TGCT cis rs7659604 0.539 rs3217773 chr4:122739121 A/G cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.24e-7 Type 2 diabetes; TGCT cis rs4730250 0.707 rs78472146 chr7:106967491 C/A cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Osteoarthritis; TGCT cis rs6570726 0.791 rs392612 chr6:145881586 C/G cg23711669 chr6:146136114 FBXO30 -0.89 -9.93 -0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs2594989 0.832 rs13325556 chr3:11566961 T/G cg00170343 chr3:11313890 ATG7 -0.69 -5.0 -0.41 1.95e-6 Circulating chemerin levels; TGCT cis rs6952808 0.771 rs10265944 chr7:1918337 C/T cg22963979 chr7:1858916 MAD1L1 -0.37 -5.81 -0.46 5.05e-8 Bipolar disorder and schizophrenia; TGCT cis rs2130392 1.000 rs873686 chr4:185638876 A/G cg14471096 chr4:185570637 CCDC111;CASP3 -0.49 -4.48 -0.37 1.68e-5 Kawasaki disease; TGCT cis rs9527 0.567 rs6584539 chr10:104879402 G/C cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs644799 1.000 rs534497 chr11:95562868 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.94e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2708977 0.666 rs17685664 chr2:97315570 C/T cg01950434 chr2:97203154 ARID5A 0.62 5.46 0.44 2.54e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1406084 0.526 rs895050 chr2:154729785 A/C cg25703346 chr2:154729189 GALNT13 0.89 4.68 0.39 7.28e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9914988 0.943 rs11658884 chr17:27132742 A/G cg20469991 chr17:27169893 C17orf63 0.72 5.09 0.42 1.28e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs7655441 0.750 rs11561687 chr4:80909951 A/C cg02241357 chr4:80885279 ANTXR2 -0.23 -4.52 -0.38 1.45e-5 Neutrophil percentage of white cells; TGCT cis rs941873 0.772 rs7920127 chr10:81122914 T/C cg09469691 chr10:81107165 PPIF 0.54 5.38 0.43 3.64e-7 Height; TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg00080972 chr5:178986291 RUFY1 -0.57 -7.17 -0.54 5.98e-11 Lung cancer; TGCT cis rs3771570 0.901 rs62190407 chr2:242405772 G/A cg21155796 chr2:242212141 HDLBP 0.89 6.82 0.52 3.55e-10 Prostate cancer; TGCT cis rs7043114 0.525 rs6479417 chr9:95064562 G/C cg14311495 chr9:95764742 FGD3 -0.22 -4.44 -0.37 1.95e-5 Height; TGCT cis rs40363 0.645 rs1690447 chr16:3519211 T/C cg21433313 chr16:3507492 NAT15 0.38 5.06 0.41 1.5e-6 Tuberculosis; TGCT cis rs6570726 0.791 rs4335004 chr6:145904764 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.12 0.42 1.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7940866 0.903 rs2324316 chr11:130872353 G/T cg12179176 chr11:130786555 SNX19 0.56 5.27 0.43 5.82e-7 Schizophrenia; TGCT cis rs9560113 1.000 rs4773383 chr13:112177764 C/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT trans rs7819412 0.775 rs34094119 chr8:10935898 A/G cg15556689 chr8:8085844 FLJ10661 -0.84 -8.16 -0.59 3.12e-13 Triglycerides; TGCT cis rs4285028 0.747 rs12496318 chr3:121561500 A/C cg01951420 chr3:121553821 IQCB1;EAF2 0.97 7.59 0.56 6.59e-12 Multiple sclerosis; TGCT cis rs12762955 0.608 rs7922760 chr10:1156815 G/C cg26597838 chr10:835615 NA -0.41 -5.08 -0.42 1.34e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs116095464 0.558 rs61689490 chr5:224904 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs6951245 0.882 rs10256720 chr7:1210825 C/G cg03188948 chr7:1209495 NA 0.77 6.26 0.49 5.77e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6121246 0.567 rs6087700 chr20:30217560 A/G cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs926938 0.618 rs904292 chr1:115358421 C/T cg12756093 chr1:115239321 AMPD1 0.42 5.97 0.47 2.28e-8 Autism; TGCT cis rs2084881 0.521 rs1022088 chr17:46579790 T/A cg25032089 chr17:46643351 HOXB3 -0.38 -4.46 -0.37 1.83e-5 Ovarian cancer; TGCT cis rs909674 0.662 rs2899318 chr22:39837625 A/G cg24399712 chr22:39784796 NA -1.05 -10.84 -0.7 1.14e-19 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT trans rs8073060 0.586 rs4796104 chr17:34046832 T/C cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs7937612 1.000 rs2305008 chr11:120319064 A/C cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.68 -0.39 7.39e-6 Intraocular pressure; TGCT cis rs9486719 1.000 rs11152959 chr6:96900272 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs6964587 1.000 rs2299240 chr7:91654618 A/G cg17063962 chr7:91808500 NA 0.92 10.17 0.67 4.92e-18 Breast cancer; TGCT cis rs3733585 0.637 rs6850684 chr4:9964380 G/T cg11266682 chr4:10021025 SLC2A9 -0.58 -7.54 -0.56 8.83e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs10504229 0.593 rs79874994 chr8:57993709 C/A cg08280861 chr8:58055591 NA 0.49 5.26 0.43 6.19e-7 Developmental language disorder (linguistic errors); TGCT cis rs208520 0.526 rs6455072 chr6:66797215 A/G cg07460842 chr6:66804631 NA -1.08 -15.99 -0.82 6.47e-32 Exhaled nitric oxide output; TGCT cis rs62103177 0.564 rs1715230 chr18:77848002 C/T cg07235805 chr18:78004237 PARD6G 0.52 5.12 0.42 1.13e-6 Opioid sensitivity; TGCT cis rs9649213 0.614 rs2240348 chr7:97984077 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.93 -8.76 -0.62 1.24e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs4713118 0.516 rs7739216 chr6:28079946 G/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Parkinson's disease; TGCT cis rs873946 0.648 rs1548281 chr10:134552982 C/T cg27286337 chr10:134555280 INPP5A 0.45 5.3 0.43 5.05e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4851254 0.660 rs74340261 chr2:100696827 C/T cg22139774 chr2:100720529 AFF3 -0.43 -4.76 -0.39 5.4e-6 Intelligence (multi-trait analysis); TGCT cis rs344364 0.511 rs1742462 chr16:1946062 A/C cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7524258 0.868 rs2157499 chr1:7271472 C/T cg07173049 chr1:7289937 CAMTA1 0.29 4.74 0.39 5.74e-6 Tourette's syndrome or obsessive-compulsive disorder; TGCT trans rs3774749 0.565 rs2518795 chr3:50208819 C/T cg21659725 chr3:3221576 CRBN 0.66 6.99 0.53 1.48e-10 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.586 rs1800359 chr16:89805261 A/G cg03388025 chr16:89894329 SPIRE2 0.33 4.84 0.4 3.83e-6 Vitiligo; TGCT cis rs11190604 1.000 rs9420785 chr10:102240451 C/G cg23241863 chr10:102295624 HIF1AN 0.64 5.04 0.41 1.59e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7829975 0.902 rs485107 chr8:8581408 C/G cg15556689 chr8:8085844 FLJ10661 -0.66 -5.77 -0.46 6.03e-8 Mood instability; TGCT cis rs2933343 1.000 rs789213 chr3:128616359 C/G cg11901034 chr3:128598214 ACAD9 0.65 5.45 0.44 2.59e-7 IgG glycosylation; TGCT cis rs2243480 1.000 rs4718334 chr7:65789454 G/A cg20637647 chr7:64974828 NA -0.88 -4.89 -0.4 3.06e-6 Diabetic kidney disease; TGCT cis rs2147959 0.883 rs7529055 chr1:228636824 T/G cg22700015 chr1:228743131 NA -0.57 -4.5 -0.37 1.55e-5 Adult asthma; TGCT cis rs1371867 0.875 rs1788184 chr8:101335106 A/G cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg09222892 chr1:25734099 RHCE 0.42 7.15 0.54 6.72e-11 Erythrocyte sedimentation rate; TGCT cis rs1129187 0.791 rs1129186 chr6:42932202 C/T cg21280719 chr6:42927975 GNMT -0.37 -4.59 -0.38 1.07e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2153535 0.623 rs6597338 chr6:8533508 A/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs3772130 0.560 rs7649585 chr3:121562300 G/C cg01951420 chr3:121553821 IQCB1;EAF2 0.6 5.54 0.45 1.76e-7 Cognitive performance; TGCT cis rs8063761 0.589 rs4238833 chr16:90050689 G/T cg08547343 chr16:90038815 CENPBD1;AFG3L1 0.68 6.71 0.52 6.1e-10 Squamous cell carcinoma; TGCT cis rs71435601 0.628 rs1367119 chr2:21386375 A/G cg25035485 chr2:21266500 APOB 0.51 4.48 0.37 1.64e-5 Cholesterol, total; TGCT cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg10047753 chr17:41438598 NA 0.77 7.44 0.56 1.43e-11 Menopause (age at onset); TGCT cis rs8177253 1.000 rs1358023 chr3:133484393 T/C cg08439880 chr3:133502540 NA -0.31 -5.88 -0.47 3.57e-8 Iron status biomarkers; TGCT cis rs7937682 0.814 rs1619652 chr11:111469757 G/A cg09085632 chr11:111637200 PPP2R1B -1.02 -10.37 -0.68 1.58e-18 Primary sclerosing cholangitis; TGCT cis rs116095464 0.558 rs59284383 chr5:284525 C/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs1056107 0.572 rs10981396 chr9:115170273 G/T cg02332936 chr9:115140584 NA 0.26 4.44 0.37 1.95e-5 Colorectal cancer; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg01802117 chr1:53393560 SCP2 -0.42 -5.06 -0.41 1.44e-6 Monocyte count; TGCT cis rs55882075 0.634 rs11249657 chr5:179111637 G/C cg14593053 chr5:179126677 CANX 0.46 4.49 0.37 1.63e-5 Monocyte percentage of white cells; TGCT cis rs8177179 0.967 rs4994581 chr3:133437563 T/C cg24879335 chr3:133465180 TF 0.35 4.73 0.39 5.96e-6 Iron status biomarkers (transferrin levels); TGCT cis rs28374715 0.532 rs28703570 chr15:41679492 G/A cg18705301 chr15:41695430 NDUFAF1 -0.94 -16.61 -0.83 2.59e-33 Ulcerative colitis; TGCT cis rs13118159 1.000 rs13118159 chr4:1365127 A/G cg20887711 chr4:1340912 KIAA1530 0.57 4.94 0.41 2.48e-6 Longevity; TGCT cis rs595982 0.501 rs112370206 chr19:49396623 C/T cg15549821 chr19:49342101 PLEKHA4 -0.41 -5.3 -0.43 5.08e-7 Red cell distribution width; TGCT cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg24846343 chr22:24311635 DDTL 0.23 5.67 0.45 9.48e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs4650994 0.816 rs2761470 chr1:178596033 G/C cg05059571 chr16:84539110 KIAA1609 0.41 7.51 0.56 1e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs7647973 0.626 rs9870858 chr3:49769071 C/T cg03060546 chr3:49711283 APEH 0.63 5.63 0.45 1.12e-7 Menarche (age at onset); TGCT cis rs7432375 0.610 rs4420814 chr3:136513282 T/C cg15507776 chr3:136538369 TMEM22 0.55 5.64 0.45 1.1e-7 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2692947 0.537 rs11164049 chr2:96345518 C/T cg22654517 chr2:96458247 NA 0.2 4.45 0.37 1.9e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6988636 0.710 rs62521805 chr8:124159200 C/T cg23067535 chr8:124195133 FAM83A -0.35 -4.71 -0.39 6.44e-6 Urinary uromodulin levels; TGCT cis rs72945132 0.882 rs57810426 chr11:70230030 G/A cg00319359 chr11:70116639 PPFIA1 1.04 7.94 0.58 1.03e-12 Coronary artery disease; TGCT cis rs10791097 0.690 rs12286234 chr11:130730528 T/C cg05962950 chr11:130786565 SNX19 0.8 9.66 0.66 8.34e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9611565 0.659 rs9611602 chr22:41908405 T/C cg06481639 chr22:41940642 POLR3H -0.72 -6.29 -0.49 4.98e-9 Vitiligo; TGCT cis rs17384381 1.000 rs12140170 chr1:85849723 G/A cg16011679 chr1:85725395 C1orf52 0.85 6.61 0.51 1.02e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089584 0.830 rs4925331 chr20:60580174 T/C cg16423285 chr20:60520624 NA -0.62 -6.86 -0.52 2.86e-10 Body mass index; TGCT cis rs3820068 0.734 rs6674806 chr1:15902656 A/G cg05660106 chr1:15850417 CASP9 1.16 14.57 0.79 1.25e-28 Systolic blood pressure; TGCT cis rs9611565 0.580 rs5758449 chr22:42140160 C/T cg06634786 chr22:41940651 POLR3H 0.79 7.29 0.55 3.13e-11 Vitiligo; TGCT trans rs3790455 0.610 rs3790458 chr1:156459699 A/T cg16443977 chr5:115884994 SEMA6A 0.41 7.18 0.54 5.72e-11 Migraine; TGCT cis rs9993613 1.000 rs2366302 chr4:73450550 T/C cg15102770 chr4:73434591 ADAMTS3 -0.5 -4.58 -0.38 1.09e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs711245 0.670 rs7560321 chr2:36822318 C/G cg09467607 chr2:36825704 FEZ2 -0.36 -5.56 -0.45 1.58e-7 Height; TGCT cis rs16958440 0.867 rs80106524 chr18:44676639 G/A cg17192377 chr18:44677553 HDHD2 0.61 4.85 0.4 3.65e-6 Sitting height ratio; TGCT cis rs13217239 0.646 rs12527111 chr6:27006475 C/T cg15659132 chr6:26577336 NA 0.54 5.44 0.44 2.78e-7 Schizophrenia; TGCT cis rs2836974 0.899 rs114399588 chr21:40653958 G/A cg11644478 chr21:40555479 PSMG1 0.98 10.28 0.68 2.68e-18 Cognitive function; TGCT cis rs9462846 0.691 rs67059212 chr6:42913269 T/G cg02353165 chr6:42928485 GNMT 0.73 5.66 0.45 1e-7 Blood protein levels; TGCT cis rs651907 0.557 rs11712748 chr3:101383562 G/A cg12386194 chr3:101231763 SENP7 0.51 5.04 0.41 1.61e-6 Colorectal cancer; TGCT cis rs10504229 0.639 rs55687236 chr8:58105856 C/T cg21724239 chr8:58056113 NA 0.48 5.12 0.42 1.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs4851266 0.966 rs11689199 chr2:100820421 A/G cg22139774 chr2:100720529 AFF3 -0.36 -5.36 -0.43 3.91e-7 Educational attainment; TGCT cis rs13108904 0.935 rs4246685 chr4:1279727 T/C cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs9653442 0.564 rs4851256 chr2:100775045 A/G cg07810366 chr2:100720526 AFF3 -0.34 -5.13 -0.42 1.09e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2354432 0.607 rs4314933 chr1:146821386 T/C cg25205988 chr1:146714368 CHD1L 1.32 6.18 0.49 8.5e-9 Mitochondrial DNA levels; TGCT cis rs8072100 0.688 rs12602134 chr17:45582136 C/G cg08085267 chr17:45401833 C17orf57 0.46 4.99 0.41 2.01e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs3812831 0.654 rs6560933 chr13:114937294 A/G cg08824895 chr13:115047677 UPF3A -0.47 -4.88 -0.4 3.18e-6 Schizophrenia; TGCT cis rs9650657 0.571 rs11783247 chr8:10788875 C/T cg27411982 chr8:10470053 RP1L1 -0.23 -4.82 -0.4 4.08e-6 Neuroticism; TGCT cis rs9650657 0.648 rs6601512 chr8:10585596 G/A cg16664915 chr8:10907788 XKR6 -0.3 -4.61 -0.38 9.67e-6 Neuroticism; TGCT cis rs9326248 0.953 rs488962 chr11:117072525 C/T cg26566898 chr11:117069891 TAGLN -0.36 -5.01 -0.41 1.8e-6 Blood protein levels; TGCT cis rs1801251 0.778 rs709933 chr2:233733144 G/A cg08000102 chr2:233561755 GIGYF2 -0.44 -4.53 -0.38 1.39e-5 Coronary artery disease; TGCT cis rs7582180 0.764 rs13001423 chr2:100925340 A/G cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.709 rs7942444 chr11:93637160 G/A cg26875233 chr11:93583750 C11orf90 0.45 5.66 0.45 9.87e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs875971 0.522 rs1701760 chr7:65473688 A/G cg00343986 chr7:65444356 GUSB 0.25 5.81 0.46 4.88e-8 Aortic root size; TGCT cis rs77861329 1.000 rs183029 chr3:52209884 A/G cg08692210 chr3:52188851 WDR51A 0.97 5.08 0.42 1.34e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs1552244 0.572 rs6797536 chr3:10168802 C/T cg02579736 chr3:10068473 FANCD2;CIDECP -0.93 -5.43 -0.44 2.89e-7 Alzheimer's disease; TGCT cis rs4819052 0.851 rs2330012 chr21:46658592 G/A cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2204008 0.747 rs11514040 chr12:38201040 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.14 0.42 1.03e-6 Bladder cancer; TGCT cis rs67311347 0.956 rs7640228 chr3:40516190 G/A cg13683864 chr3:40499215 RPL14 1.18 13.19 0.76 2.28e-25 Renal cell carcinoma; TGCT cis rs526231 0.783 rs28158 chr5:102595892 C/G cg05225461 chr5:102596755 C5orf30 0.22 4.49 0.37 1.64e-5 Primary biliary cholangitis; TGCT cis rs6490294 0.583 rs1005902 chr12:112667675 G/T cg10833066 chr12:111807467 FAM109A -0.34 -5.22 -0.42 7.39e-7 Mean platelet volume; TGCT cis rs854765 0.964 rs854764 chr17:18011750 A/G cg09796270 chr17:17721594 SREBF1 -0.27 -5.53 -0.45 1.78e-7 Total body bone mineral density; TGCT cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.65 -6.6 -0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs137603 0.602 rs9611146 chr22:39718120 G/T cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.7 -0.39 6.73e-6 Primary biliary cholangitis; TGCT cis rs2153535 0.580 rs1577468 chr6:8444266 C/A cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg11062466 chr8:58055876 NA 0.38 4.5 0.37 1.56e-5 Developmental language disorder (linguistic errors); TGCT cis rs4930561 0.714 rs10896300 chr11:67953772 C/T cg04465784 chr11:67976953 SUV420H1 0.4 5.53 0.44 1.79e-7 Breast cancer in childhood cancer survivors;IgG glycosylation; TGCT cis rs1218582 0.772 rs10908448 chr1:154882544 A/G cg06418219 chr1:154948305 SHC1;CKS1B 0.69 6.98 0.53 1.61e-10 Prostate cancer; TGCT cis rs7666738 0.830 rs13133619 chr4:99067312 C/G cg05340658 chr4:99064831 C4orf37 -0.53 -5.98 -0.47 2.23e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2072499 0.750 rs72708291 chr1:156177285 A/T cg25208724 chr1:156163844 SLC25A44 0.98 8.96 0.63 4e-15 Testicular germ cell tumor; TGCT cis rs11209185 0.509 rs9326078 chr1:68452388 A/G cg22082780 chr1:68452167 NA 0.32 5.07 0.41 1.39e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT trans rs28735056 0.904 rs12953738 chr18:77627877 A/G cg05926928 chr17:57297772 GDPD1 0.65 6.74 0.52 5.44e-10 Schizophrenia; TGCT cis rs6964587 0.692 rs10236483 chr7:91797296 A/C cg17063962 chr7:91808500 NA 0.74 6.94 0.53 1.93e-10 Breast cancer; TGCT cis rs950169 0.580 rs11635597 chr15:85165699 C/T cg12863693 chr15:85201151 NMB 0.44 5.25 0.43 6.32e-7 Schizophrenia; TGCT cis rs9527 0.590 rs2148200 chr10:104879847 C/A cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs9733 0.596 rs72702585 chr1:150696427 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs3087591 0.920 rs7225014 chr17:29572973 A/G cg24425628 chr17:29625626 OMG;NF1 -0.47 -7.26 -0.55 3.82e-11 Hip circumference; TGCT cis rs9549367 0.789 rs9577218 chr13:113894911 A/G cg00898013 chr13:113819073 PROZ -0.43 -5.55 -0.45 1.68e-7 Platelet distribution width; TGCT cis rs308403 0.568 rs13135778 chr4:123664446 G/A cg10495464 chr4:123653540 BBS12;LOC729338 0.7 6.51 0.5 1.66e-9 Blood protein levels; TGCT cis rs909674 0.690 rs5750823 chr22:39829973 C/T cg02038168 chr22:39784481 NA -0.74 -5.67 -0.45 9.63e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2455799 0.613 rs4467435 chr3:15791671 A/G cg16303742 chr3:15540471 COLQ -0.25 -4.88 -0.4 3.18e-6 Mean platelet volume; TGCT cis rs1801251 1.000 rs283474 chr2:233654627 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.38 0.5 3.2e-9 Coronary artery disease; TGCT cis rs210152 0.531 rs4713634 chr6:33514708 T/C cg16739976 chr6:34101401 GRM4 -0.63 -5.2 -0.42 8e-7 Schizophrenia; TGCT cis rs79349575 0.721 rs2291725 chr17:47039132 T/C cg07967210 chr17:47022446 SNF8 0.45 6.15 0.48 9.7e-9 Type 2 diabetes; TGCT cis rs1799949 0.602 rs8176257 chr17:41216205 G/T cg10047753 chr17:41438598 NA 0.81 6.37 0.5 3.42e-9 Menopause (age at onset); TGCT cis rs6500596 0.570 rs8055628 chr16:4447477 G/A cg02873098 chr16:4524103 NMRAL1;HMOX2 0.39 4.93 0.41 2.55e-6 Schizophrenia; TGCT cis rs6951245 1.000 rs80031817 chr7:1096793 T/C cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9929218 0.954 rs12928043 chr16:68828885 G/A cg03880890 chr16:69439245 NA -0.23 -4.62 -0.38 9.31e-6 Colorectal cancer; TGCT cis rs2032447 0.677 rs199737 chr6:25933538 A/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.86 8.27 0.6 1.72e-13 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.715 rs7586608 chr2:99558017 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.51 -0.38 1.46e-5 Chronic sinus infection; TGCT cis rs7845219 0.525 rs3019175 chr8:95949013 G/A cg09323728 chr8:95962352 TP53INP1 -0.4 -4.56 -0.38 1.23e-5 Type 2 diabetes; TGCT cis rs10504229 0.773 rs1874373 chr8:58194423 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs12368653 0.534 rs923828 chr12:58015494 G/A cg12615879 chr12:58013172 SLC26A10 0.6 6.78 0.52 4.26e-10 Multiple sclerosis; TGCT cis rs11874712 1.000 rs11874712 chr18:43688576 C/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.09 0.42 1.29e-6 Migraine - clinic-based; TGCT cis rs9436747 0.567 rs10889564 chr1:66053488 C/A cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.68 0.39 7.45e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.96 7.8 0.57 2.16e-12 Platelet count; TGCT cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg15691649 chr6:25882328 NA 0.33 4.44 0.37 1.99e-5 Blood metabolite levels; TGCT cis rs4242434 0.536 rs1871900 chr8:22481449 A/G cg03733263 chr8:22462867 KIAA1967 0.91 11.75 0.73 6.81e-22 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7666738 0.830 rs7659593 chr4:98934823 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9486719 0.947 rs2472908 chr6:96875998 A/T cg18709589 chr6:96969512 KIAA0776 0.71 5.2 0.42 8.13e-7 Migraine;Coronary artery disease; TGCT trans rs916888 0.647 rs199524 chr17:44848438 G/T cg22968622 chr17:43663579 NA -1.05 -10.06 -0.67 8.89e-18 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs16921914 0.565 rs286650 chr11:31230207 T/C cg26647111 chr11:31128758 NA -0.34 -4.73 -0.39 5.88e-6 Bone mineral density (spine); TGCT cis rs7635838 0.892 rs7644968 chr3:11489493 C/T cg00170343 chr3:11313890 ATG7 0.64 6.08 0.48 1.38e-8 HDL cholesterol; TGCT cis rs7020830 0.858 rs7856690 chr9:37127545 A/T cg14294708 chr9:37120828 ZCCHC7 1.17 16.08 0.82 3.91e-32 Schizophrenia; TGCT cis rs10504229 0.593 rs75047131 chr8:58001320 A/G cg02725872 chr8:58115012 NA -0.4 -4.85 -0.4 3.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs57590327 0.555 rs3772909 chr3:81707264 T/C cg07356753 chr3:81810745 GBE1 -0.78 -7.07 -0.54 1.01e-10 Extraversion; TGCT cis rs7772486 0.720 rs4896837 chr6:146014168 C/T cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT trans rs7618501 0.633 rs35065728 chr3:50009176 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.38 0.64 3.95e-16 Intelligence (multi-trait analysis); TGCT cis rs9638182 0.725 rs75229905 chr7:72895946 T/C cg14087351 chr7:73037990 MLXIPL -0.61 -4.81 -0.4 4.34e-6 Triglycerides; TGCT cis rs9296092 0.517 rs113111213 chr6:33520790 A/G cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg07061783 chr6:25882402 NA -0.58 -5.62 -0.45 1.21e-7 Intelligence (multi-trait analysis); TGCT cis rs4706831 0.647 rs9350847 chr6:80889017 C/T cg08355045 chr6:80787529 NA 0.29 5.03 0.41 1.66e-6 Joint mobility (Beighton score); TGCT cis rs1865760 0.566 rs9358902 chr6:26058570 C/G cg17042849 chr6:26104293 HIST1H4C -0.62 -5.41 -0.44 3.18e-7 Height; TGCT cis rs9527 0.551 rs28606370 chr10:104670832 C/A cg15744005 chr10:104629667 AS3MT -0.43 -5.38 -0.44 3.54e-7 Arsenic metabolism; TGCT cis rs72843506 0.591 rs117720402 chr17:20347611 C/T cg18979559 chr17:20280153 CCDC144C -0.65 -4.78 -0.39 4.96e-6 Schizophrenia; TGCT cis rs1729951 0.575 rs16844326 chr3:136678385 G/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs9682041 0.688 rs7621787 chr3:170146862 T/A cg11886554 chr3:170076028 SKIL 0.95 6.87 0.52 2.8e-10 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs769267 0.931 rs2965193 chr19:19454828 G/A cg19010396 chr19:19431384 KIAA0892;SF4 -0.54 -4.54 -0.38 1.3e-5 Tonsillectomy; TGCT cis rs17253792 0.822 rs78820104 chr14:56068854 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6815814 0.861 rs10012017 chr4:38784633 G/T cg02016764 chr4:38805732 TLR1 -0.27 -4.46 -0.37 1.78e-5 Breast cancer; TGCT cis rs3862260 0.509 rs2281493 chr1:120162787 T/C cg16322792 chr1:120165303 ZNF697 0.35 8.36 0.6 1.07e-13 Systemic lupus erythematosus; TGCT cis rs57590327 0.503 rs6776737 chr3:81513729 T/C cg07356753 chr3:81810745 GBE1 0.58 4.89 0.4 3.06e-6 Extraversion; TGCT cis rs651907 0.535 rs11714444 chr3:101513682 G/A cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs9291683 0.632 rs7679916 chr4:10042160 C/T cg00071950 chr4:10020882 SLC2A9 0.68 8.74 0.62 1.38e-14 Bone mineral density; TGCT cis rs7772486 0.754 rs4896832 chr6:145964151 G/A cg23711669 chr6:146136114 FBXO30 0.88 9.78 0.66 4.39e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.694 rs202665 chr22:41814401 A/G cg06481639 chr22:41940642 POLR3H 0.72 6.4 0.5 2.96e-9 Vitiligo; TGCT cis rs1552244 0.572 rs3894322 chr3:10168965 G/A cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs950169 0.922 rs11633534 chr15:85124642 C/T cg11189052 chr15:85197271 WDR73 0.78 6.44 0.5 2.42e-9 Schizophrenia; TGCT cis rs1552244 1.000 rs35198334 chr3:10104553 G/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs10504229 0.636 rs77290284 chr8:58055269 G/T cg20607798 chr8:58055168 NA 0.62 5.19 0.42 8.32e-7 Developmental language disorder (linguistic errors); TGCT trans rs561341 0.825 rs2008368 chr17:30347397 T/C cg20587970 chr11:113659929 NA -1.06 -13.47 -0.77 4.88e-26 Hip circumference adjusted for BMI; TGCT cis rs28595532 0.841 rs56388366 chr4:119769242 A/G cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs4927850 1.000 rs10881563 chr3:195750225 A/G cg22891161 chr3:195456627 MUC20 -0.21 -4.65 -0.39 8.3e-6 Pancreatic cancer; TGCT cis rs854765 0.583 rs4925126 chr17:17798633 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.53 0.56 9.12e-12 Total body bone mineral density; TGCT cis rs2739330 0.760 rs1002286 chr22:24257337 A/G cg18538332 chr22:24372958 LOC391322 0.87 10.04 0.67 1.04e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7542091 0.506 rs992976 chr1:210066658 A/T cg21951975 chr1:209979733 IRF6 -0.53 -5.24 -0.43 6.58e-7 Monobrow; TGCT cis rs2404602 0.655 rs34748201 chr15:77221530 G/T cg26408565 chr15:76604113 ETFA -0.37 -4.63 -0.38 9.04e-6 Blood metabolite levels; TGCT cis rs11741688 0.557 rs6600994 chr5:178336005 T/A cg09339527 chr5:178322752 ZFP2 -0.29 -4.85 -0.4 3.57e-6 Sleep duration; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg11235426 chr6:292522 DUSP22 -0.69 -6.94 -0.53 1.93e-10 Menopause (age at onset); TGCT cis rs7945705 0.747 rs1980429 chr11:9010474 C/A cg21881798 chr11:8931708 C11orf17;ST5 -0.44 -4.78 -0.39 4.95e-6 Hemoglobin concentration; TGCT cis rs6912958 0.781 rs6940150 chr6:88287114 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs734999 0.588 rs3748817 chr1:2525665 T/C cg18854424 chr1:2615690 NA 0.5 5.78 0.46 5.64e-8 Ulcerative colitis; TGCT cis rs4699052 0.963 rs11097801 chr4:104150323 A/G cg16532752 chr4:104119610 CENPE -0.59 -5.58 -0.45 1.41e-7 Testicular germ cell tumor; TGCT cis rs7010267 0.687 rs13264791 chr8:120013090 A/G cg17171407 chr8:119960777 TNFRSF11B 0.29 5.4 0.44 3.25e-7 Total body bone mineral density (age 45-60); TGCT cis rs9796 0.561 rs7173086 chr15:41509288 A/T cg18705301 chr15:41695430 NDUFAF1 -0.5 -6.78 -0.52 4.32e-10 Menopause (age at onset); TGCT cis rs6089584 0.861 rs2180302 chr20:60576369 A/G cg23262073 chr20:60523788 NA -0.31 -4.63 -0.38 8.99e-6 Body mass index; TGCT cis rs9611565 0.694 rs5758389 chr22:41941749 T/C cg13695892 chr22:41940480 POLR3H -0.86 -9.05 -0.63 2.46e-15 Vitiligo; TGCT cis rs514406 0.861 rs2448792 chr1:53268313 T/C cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs10540 1.000 rs35874808 chr11:506442 G/T cg03934478 chr11:495069 RNH1 0.35 5.77 0.46 6.03e-8 Body mass index; TGCT cis rs4665809 0.590 rs1865324 chr2:26417533 C/A cg25036284 chr2:26402008 FAM59B -0.61 -4.9 -0.4 2.92e-6 Gut microbiome composition (summer); TGCT cis rs8103278 0.507 rs3745802 chr19:46271177 G/T cg14061069 chr19:46274453 DMPK 0.62 10.71 0.69 2.44e-19 Coronary artery disease; TGCT cis rs9291683 0.546 rs13146686 chr4:10034933 A/G cg00071950 chr4:10020882 SLC2A9 0.58 6.08 0.48 1.39e-8 Bone mineral density; TGCT cis rs4654899 0.571 rs1888759 chr1:21065167 G/A cg01072550 chr1:21505969 NA -0.52 -8.59 -0.61 3.04e-14 Superior frontal gyrus grey matter volume; TGCT cis rs7552404 1.000 rs6593585 chr1:76140273 G/A cg10523679 chr1:76189770 ACADM 0.91 9.92 0.67 2.01e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7662987 0.517 rs2602865 chr4:100034841 T/C cg12011299 chr4:100065546 ADH4 0.39 4.81 0.4 4.36e-6 Smoking initiation; TGCT cis rs3125734 0.633 rs3902162 chr10:64041817 C/T cg19640130 chr10:64028056 RTKN2 -0.38 -4.82 -0.4 4.15e-6 Rheumatoid arthritis; TGCT cis rs7178572 0.568 rs1823100 chr15:77402744 C/T cg22256960 chr15:77711686 NA -0.86 -8.84 -0.62 8.05e-15 Type 2 diabetes; TGCT cis rs9611565 0.512 rs768414 chr22:42135751 T/C cg13695892 chr22:41940480 POLR3H 0.89 8.43 0.6 7.37e-14 Vitiligo; TGCT cis rs12477438 0.735 rs12474477 chr2:99690408 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.47 -0.61 5.8e-14 Chronic sinus infection; TGCT cis rs921968 0.541 rs12619347 chr2:219419935 T/C cg02176678 chr2:219576539 TTLL4 -0.49 -6.94 -0.53 1.95e-10 Mean corpuscular hemoglobin concentration; TGCT trans rs1005277 0.579 rs1740737 chr10:38499365 G/T cg27523141 chr10:43048294 ZNF37B 0.73 8.5 0.61 5.19e-14 Extrinsic epigenetic age acceleration; TGCT trans rs7618501 0.602 rs34831713 chr3:50118748 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.5 -0.65 2.02e-16 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.724 rs9753987 chr21:46661389 C/T cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs896854 0.812 rs2340586 chr8:95969261 G/A cg23172400 chr8:95962367 TP53INP1 -0.4 -6.65 -0.51 8.46e-10 Type 2 diabetes; TGCT cis rs7582180 0.590 rs11123828 chr2:100960918 T/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.86 -0.4 3.52e-6 Intelligence (multi-trait analysis); TGCT cis rs2721195 0.719 rs4925812 chr8:145808035 C/T cg15320075 chr8:145703422 NA 0.75 7.27 0.55 3.62e-11 Age at first birth; TGCT cis rs7666738 0.791 rs10856933 chr4:98958542 C/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6714710 0.580 rs13032265 chr2:98409565 T/C cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs1775715 1.000 rs1251355 chr10:32290146 C/G cg14930904 chr10:32216787 ARHGAP12 0.51 4.77 0.39 5.14e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs9419702 0.568 rs10782366 chr10:133557866 G/A cg04492858 chr10:133558786 NA 0.57 5.92 0.47 2.89e-8 Survival in rectal cancer; TGCT cis rs7945705 1.000 rs4910062 chr11:8862188 A/C cg21881798 chr11:8931708 C11orf17;ST5 0.41 4.56 0.38 1.23e-5 Hemoglobin concentration; TGCT cis rs9549367 0.756 rs9603814 chr13:113900782 C/T cg00898013 chr13:113819073 PROZ 0.4 5.07 0.41 1.39e-6 Platelet distribution width; TGCT cis rs9393692 0.645 rs9467703 chr6:26318903 A/G cg00631329 chr6:26305371 NA -0.47 -6.94 -0.53 1.89e-10 Educational attainment; TGCT cis rs4660261 0.561 rs11210934 chr1:44369435 G/A cg13606994 chr1:44402422 ARTN -0.42 -4.61 -0.38 1e-5 Intelligence (multi-trait analysis); TGCT cis rs9486719 1.000 rs4262195 chr6:96929475 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.77 -0.62 1.18e-14 Migraine;Coronary artery disease; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg20007245 chr22:24372913 LOC391322 -0.65 -6.44 -0.5 2.34e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836633 1.000 rs2836634 chr21:40068230 T/A cg05519781 chr21:40033154 ERG 0.56 5.47 0.44 2.36e-7 Coronary artery disease; TGCT cis rs7524258 0.868 rs7538921 chr1:7267007 T/C cg07173049 chr1:7289937 CAMTA1 0.31 5.29 0.43 5.39e-7 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs1153858 1.000 rs7179743 chr15:45638331 G/C cg26924012 chr15:45694286 SPATA5L1 1.07 14.56 0.79 1.32e-28 Homoarginine levels; TGCT cis rs9611565 0.512 rs964899 chr22:42142386 G/A cg03806693 chr22:41940476 POLR3H 0.99 9.96 0.67 1.57e-17 Vitiligo; TGCT cis rs3764400 0.567 rs12946208 chr17:46312129 G/A cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs9814567 1.000 rs9289475 chr3:134236459 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -8.81 -0.62 9.26e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1691799 0.867 rs1168332 chr12:66761548 C/T cg16791601 chr12:66731901 HELB -0.28 -6.03 -0.48 1.74e-8 White blood cell count (basophil); TGCT cis rs2242116 0.727 rs6442040 chr3:46963035 C/A cg23352942 chr3:46931381 PTH1R -0.33 -4.91 -0.4 2.81e-6 Birth weight; TGCT cis rs2718812 0.766 rs11924101 chr3:133394478 T/G cg16414030 chr3:133502952 NA -0.4 -5.2 -0.42 8.03e-7 Iron status biomarkers; TGCT cis rs2439831 0.681 rs540388 chr15:43606494 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.51 0.61 4.91e-14 Lung cancer in ever smokers; TGCT cis rs7666738 0.830 rs34870112 chr4:99045815 T/G cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT trans rs208520 0.690 rs3899423 chr6:66835285 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs7904368 0.707 rs12253979 chr10:16853415 T/C cg14835575 chr10:16859367 RSU1 0.71 7.37 0.55 2.16e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs6951245 1.000 rs76129108 chr7:1089159 G/A cg18402987 chr7:1209562 NA 0.74 6.21 0.49 7.23e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1371867 0.875 rs7830342 chr8:101327738 T/A cg06636551 chr8:101224915 SPAG1 -0.42 -5.65 -0.45 1.06e-7 Atrioventricular conduction; TGCT cis rs2836974 0.897 rs4817996 chr21:40525759 G/C cg11644478 chr21:40555479 PSMG1 1.02 10.86 0.7 1.05e-19 Cognitive function; TGCT cis rs7659604 1.000 rs72678650 chr4:122666000 A/G cg19748678 chr4:122722346 EXOSC9 0.55 5.31 0.43 4.92e-7 Type 2 diabetes; TGCT cis rs6901250 0.589 rs684023 chr6:117092308 T/C cg12892004 chr6:117198278 RFX6 0.38 4.81 0.4 4.38e-6 C-reactive protein levels; TGCT cis rs9388451 0.536 rs34725880 chr6:126155237 A/G cg05901451 chr6:126070800 HEY2 -0.73 -7.57 -0.56 7.38e-12 Brugada syndrome; TGCT cis rs1862618 0.526 rs2591963 chr5:56237135 T/A cg18230493 chr5:56204884 C5orf35 0.86 6.85 0.52 3.07e-10 Initial pursuit acceleration; TGCT cis rs10504229 0.773 rs1874374 chr8:58194422 A/G cg24829409 chr8:58192753 C8orf71 -0.64 -5.31 -0.43 4.89e-7 Developmental language disorder (linguistic errors); TGCT cis rs611744 0.625 rs4735055 chr8:109286642 G/A cg21045802 chr8:109455806 TTC35 0.76 7.97 0.58 8.77e-13 Dupuytren's disease; TGCT cis rs10504229 0.639 rs11781834 chr8:58133422 C/T cg02725872 chr8:58115012 NA -0.36 -4.78 -0.39 4.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs9467773 1.000 rs2224380 chr6:26553943 G/A cg26531700 chr6:26746687 NA 0.48 4.72 0.39 6.37e-6 Intelligence (multi-trait analysis); TGCT cis rs2235642 0.859 rs9927529 chr16:1619488 C/T cg07341220 chr16:1583899 IFT140;TMEM204 -0.31 -4.51 -0.38 1.46e-5 Coronary artery disease; TGCT cis rs78707713 0.560 rs61848397 chr10:71225584 C/A cg12610070 chr10:71211762 TSPAN15 -0.62 -7.37 -0.55 2.14e-11 Venous thromboembolism; TGCT cis rs916888 0.773 rs199534 chr17:44824213 T/G cg16228356 chr17:43848958 NA -0.26 -4.53 -0.38 1.37e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs60871478 1.000 rs34260834 chr7:822958 A/G cg05729249 chr7:766119 PRKAR1B;HEATR2 0.48 4.66 0.39 7.91e-6 Cerebrospinal P-tau181p levels; TGCT cis rs2120019 0.567 rs8037152 chr15:75156996 A/T cg09165964 chr15:75287851 SCAMP5 -0.83 -6.46 -0.5 2.12e-9 Blood trace element (Zn levels); TGCT cis rs1371867 0.817 rs1788179 chr8:101333345 A/G cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs6121246 0.909 rs6088962 chr20:30268184 C/T cg13852791 chr20:30311386 BCL2L1 0.68 4.79 0.4 4.6e-6 Mean corpuscular hemoglobin; TGCT trans rs7618501 0.699 rs2777888 chr3:49898000 A/G cg21659725 chr3:3221576 CRBN 0.79 9.28 0.64 6.9e-16 Intelligence (multi-trait analysis); TGCT cis rs7312933 0.584 rs6582395 chr12:42700141 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.57 5.31 0.43 4.8e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs1799949 1.000 rs8176269 chr17:41213626 G/T cg10047753 chr17:41438598 NA 0.95 9.0 0.63 3.2e-15 Menopause (age at onset); TGCT cis rs9467773 1.000 rs2255070 chr6:26501777 C/G cg05738196 chr6:26577821 NA 0.87 12.23 0.74 4.65e-23 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs9328478 chr6:8519183 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs8017423 0.935 rs2149653 chr14:90669333 G/A cg04374321 chr14:90722782 PSMC1 0.77 7.95 0.58 9.78e-13 Mortality in heart failure; TGCT cis rs2228479 0.867 rs34272502 chr16:89949000 G/C cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs17102423 0.594 rs10151162 chr14:65566695 T/C cg11161011 chr14:65562177 MAX -0.46 -6.3 -0.49 4.84e-9 Obesity-related traits; TGCT cis rs367943 0.966 rs348924 chr5:112817930 T/G cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs12971120 0.947 rs7241558 chr18:72169267 A/T cg26446133 chr18:72167187 CNDP2 -0.4 -7.77 -0.57 2.58e-12 Refractive error; TGCT trans rs1814175 0.817 rs7929173 chr11:49944007 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.12 -0.54 7.75e-11 Height; TGCT cis rs13427251 0.903 rs6746402 chr2:100150443 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.51 -4.51 -0.38 1.49e-5 Chronic sinus infection; TGCT cis rs3770081 0.793 rs60719866 chr2:86284378 A/G cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.56 -0.38 1.21e-5 Facial emotion recognition (sad faces); TGCT cis rs4478858 0.735 rs6679365 chr1:31787866 A/C cg07478791 chr1:31886160 SERINC2 0.52 5.03 0.41 1.67e-6 Alcohol dependence; TGCT cis rs933688 0.818 rs10052492 chr5:90759930 T/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.06 10.58 0.69 4.94e-19 Smoking behavior; TGCT cis rs2072499 0.966 rs6427307 chr1:156190083 A/G cg24450063 chr1:156163899 SLC25A44 1.14 16.5 0.83 4.43e-33 Testicular germ cell tumor; TGCT cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.46e-6 Menopause (age at onset); TGCT cis rs2692947 0.727 rs749457 chr2:96795944 A/G cg23100626 chr2:96804247 ASTL 0.41 5.06 0.41 1.46e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs4321325 0.536 rs10198483 chr2:127934102 G/A cg09760422 chr2:128146352 NA 0.44 4.81 0.4 4.31e-6 Protein C levels; TGCT trans rs7613875 0.620 rs2526747 chr3:50082914 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.82 8.52 0.61 4.53e-14 Body mass index; TGCT cis rs7677751 0.806 rs1800813 chr4:55094467 G/A cg17187183 chr4:55093834 PDGFRA 0.56 7.08 0.54 9.52e-11 Corneal astigmatism; TGCT trans rs797680 0.856 rs12030549 chr1:93669218 T/C cg27528825 chr2:159282178 CCDC148 -0.35 -6.8 -0.52 3.95e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1801251 0.964 rs7589201 chr2:233724536 A/G cg08000102 chr2:233561755 GIGYF2 -0.63 -6.36 -0.5 3.57e-9 Coronary artery disease; TGCT cis rs1670533 1.000 rs11735663 chr4:1051845 C/T cg27284194 chr4:1044797 NA 0.68 5.8 0.46 5.11e-8 Recombination rate (females); TGCT cis rs10789491 1.000 rs1440487 chr1:47167075 C/T cg15501359 chr1:47185051 KIAA0494 -0.81 -8.17 -0.59 2.99e-13 Response to hepatitis C treatment; TGCT cis rs644799 0.687 rs3748252 chr11:95519195 A/T cg25622487 chr11:95524042 FAM76B;CEP57 -0.8 -8.74 -0.62 1.4e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4253772 0.591 rs6008545 chr22:46686375 C/T cg24881330 chr22:46731750 TRMU 0.93 6.08 0.48 1.36e-8 LDL cholesterol;Cholesterol, total; TGCT cis rs10504229 1.000 rs1961778 chr8:58168756 G/A cg21724239 chr8:58056113 NA 0.39 5.29 0.43 5.44e-7 Developmental language disorder (linguistic errors); TGCT cis rs3087591 0.919 rs2285892 chr17:29553485 G/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.42 -0.55 1.64e-11 Hip circumference; TGCT cis rs2404602 0.669 rs9788684 chr15:77194838 A/T cg22467129 chr15:76604101 ETFA -0.48 -5.45 -0.44 2.56e-7 Blood metabolite levels; TGCT cis rs950169 0.580 rs62021208 chr15:85196244 G/A cg11189052 chr15:85197271 WDR73 0.76 6.33 0.49 4.04e-9 Schizophrenia; TGCT cis rs778371 0.723 rs12993791 chr2:233690082 C/T cg08000102 chr2:233561755 GIGYF2 -0.69 -7.77 -0.57 2.62e-12 Schizophrenia; TGCT cis rs1403694 0.515 rs1648699 chr3:186449890 G/C cg12454167 chr3:186435060 KNG1 0.46 7.19 0.54 5.47e-11 Blood protein levels; TGCT cis rs137699 0.652 rs137706 chr22:39751400 T/G cg05872129 chr22:39784769 NA -0.73 -5.62 -0.45 1.2e-7 IgG glycosylation; TGCT cis rs4689388 0.926 rs3821940 chr4:6286711 C/A cg00701064 chr4:6280414 WFS1 0.45 5.98 0.47 2.18e-8 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4455778 0.580 rs56068416 chr7:49083226 T/C cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs916888 0.821 rs199504 chr17:44861003 C/T cg01570182 chr17:44337453 NA -1.01 -9.11 -0.63 1.74e-15 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs17221829 0.616 rs75627051 chr11:89360903 C/T cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg13877915 chr19:58951672 ZNF132 0.92 11.82 0.73 4.64e-22 Uric acid clearance; TGCT cis rs1129187 0.755 rs2274514 chr6:42934500 C/T cg13397359 chr6:42928475 GNMT 0.72 6.48 0.5 1.93e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6570726 0.846 rs6919684 chr6:145883801 A/G cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs422249 0.512 rs174568 chr11:61593816 C/T cg01500311 chr11:61656094 FADS3 -0.3 -5.25 -0.43 6.42e-7 Trans fatty acid levels; TGCT cis rs7824557 0.602 rs35807737 chr8:11204411 C/G cg21775007 chr8:11205619 TDH 0.72 7.02 0.53 1.27e-10 Retinal vascular caliber; TGCT cis rs1552244 0.935 rs35148833 chr3:10116937 C/A cg00149659 chr3:10157352 C3orf10 0.93 6.0 0.47 2.05e-8 Alzheimer's disease; TGCT cis rs1008375 0.866 rs12233712 chr4:17570063 T/A cg10189774 chr4:17578691 LAP3 0.57 5.08 0.41 1.36e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12200560 0.505 rs211163 chr6:97067654 A/G cg06623918 chr6:96969491 KIAA0776 0.57 4.83 0.4 3.93e-6 Coronary heart disease; TGCT trans rs17206232 0.534 rs6877731 chr5:64695717 C/T cg17738841 chr2:31094363 NA 0.7 6.95 0.53 1.85e-10 Schizophrenia; TGCT cis rs593982 0.688 rs3897552 chr11:65560880 C/T cg08755490 chr11:65554678 OVOL1 -1.24 -8.42 -0.6 8e-14 Atopic dermatitis; TGCT cis rs2251381 0.750 rs2251087 chr21:30527999 C/T cg08807101 chr21:30365312 RNF160 0.53 4.65 0.39 8.51e-6 Selective IgA deficiency; TGCT cis rs3924048 0.547 rs72642661 chr1:12612873 C/G cg00291366 chr1:12616550 NA 0.35 5.38 0.44 3.55e-7 Optic cup area; TGCT cis rs3733585 0.673 rs10000983 chr4:9951606 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.5 -0.56 1.04e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6964587 0.900 rs4279 chr7:91764128 C/A cg22709100 chr7:91322751 NA 0.29 4.55 0.38 1.26e-5 Breast cancer; TGCT cis rs4975616 0.804 rs381949 chr5:1322468 G/A cg06550200 chr5:1325588 CLPTM1L -0.29 -4.55 -0.38 1.28e-5 Lung cancer; TGCT cis rs6598955 0.543 rs79778574 chr1:26538482 A/G cg04990556 chr1:26633338 UBXN11 0.82 7.9 0.58 1.31e-12 Obesity-related traits; TGCT cis rs11997175 0.819 rs6415400 chr8:33783714 C/T ch.8.33884649F chr8:33765107 NA 0.34 5.33 0.43 4.57e-7 Body mass index; TGCT cis rs62244186 0.535 rs59726036 chr3:44850074 G/T cg25151919 chr3:44754333 ZNF502 -0.44 -4.94 -0.41 2.48e-6 Depressive symptoms; TGCT cis rs2842992 0.724 rs1128670 chr6:160211636 G/A cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs919433 0.679 rs6757669 chr2:198530355 C/T cg00792783 chr2:198669748 PLCL1 0.55 4.93 0.4 2.56e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs727505 1.000 rs3925331 chr7:124446137 C/G cg23710748 chr7:124431027 NA -0.27 -4.59 -0.38 1.09e-5 Lewy body disease; TGCT cis rs12950390 0.853 rs4794107 chr17:45843159 T/G cg06532163 chr17:45867833 NA 0.34 5.31 0.43 4.82e-7 IgG glycosylation; TGCT cis rs7246657 0.943 rs713256 chr19:37865365 C/T cg18154014 chr19:37997991 ZNF793 1.0 6.69 0.52 6.81e-10 Coronary artery calcification; TGCT cis rs11098499 0.754 rs66900435 chr4:120249425 C/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs1775715 0.707 rs2799024 chr10:32166922 A/G cg14930904 chr10:32216787 ARHGAP12 0.53 5.03 0.41 1.66e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs875971 1.000 rs6963646 chr7:65685767 T/C cg18876405 chr7:65276391 NA -0.32 -4.92 -0.4 2.72e-6 Aortic root size; TGCT cis rs28595532 0.748 rs72670258 chr4:119391660 A/T cg11846333 chr4:119757529 SEC24D 0.69 4.51 0.38 1.48e-5 Cannabis dependence symptom count; TGCT cis rs28712821 0.930 rs11940694 chr4:39414993 C/T cg16714752 chr4:39368184 RFC1 -0.36 -4.83 -0.4 3.94e-6 Alcohol consumption; TGCT cis rs17376456 0.877 rs10476597 chr5:93367172 C/T cg25358565 chr5:93447407 FAM172A -1.02 -8.64 -0.61 2.31e-14 Diabetic retinopathy; TGCT cis rs875971 0.723 rs28391294 chr7:65654315 T/C cg11764359 chr7:65958608 NA -0.56 -5.06 -0.41 1.45e-6 Aortic root size; TGCT cis rs9549367 0.713 rs3024747 chr13:113821787 C/G cg18105134 chr13:113819100 PROZ -0.47 -8.21 -0.59 2.49e-13 Platelet distribution width; TGCT cis rs346785 0.692 rs9900514 chr17:74285595 T/C cg09812376 chr17:74270190 QRICH2 -0.37 -5.55 -0.45 1.65e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs2996428 0.601 rs10909804 chr1:3770929 A/G cg13057898 chr1:3703894 LRRC47 -0.21 -4.64 -0.38 8.81e-6 Red cell distribution width; TGCT cis rs6087990 0.669 rs2424929 chr20:31389518 A/G cg13636640 chr20:31349939 DNMT3B 0.97 12.84 0.76 1.63e-24 Ulcerative colitis; TGCT cis rs6087990 0.899 rs1003521 chr20:31366598 T/C cg13636640 chr20:31349939 DNMT3B 1.08 14.22 0.79 8.35e-28 Ulcerative colitis; TGCT cis rs2549003 1.000 rs2070731 chr5:131819798 T/C cg02551604 chr5:131831745 NA -0.83 -10.59 -0.69 4.58e-19 Asthma (sex interaction); TGCT cis rs2594989 0.616 rs6442255 chr3:11474492 A/G cg00170343 chr3:11313890 ATG7 0.74 5.52 0.44 1.9e-7 Circulating chemerin levels; TGCT cis rs9677476 0.516 rs1549339 chr2:231982826 G/A cg07929768 chr2:232055508 NA 0.34 5.23 0.43 7.03e-7 Food antigen IgG levels; TGCT cis rs7523050 0.730 rs12726126 chr1:109436128 A/G cg08274380 chr1:109419600 GPSM2 1.35 6.86 0.52 2.89e-10 Fat distribution (HIV); TGCT cis rs9921338 0.887 rs13330151 chr16:11402399 C/T cg00044050 chr16:11439710 C16orf75 -0.97 -6.94 -0.53 1.94e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs1153858 1.000 rs59889118 chr15:45618730 G/A cg26924012 chr15:45694286 SPATA5L1 1.07 14.11 0.79 1.45e-27 Homoarginine levels; TGCT cis rs9911578 0.867 rs72628394 chr17:57121313 C/T cg05425664 chr17:57184151 TRIM37 0.63 6.3 0.49 4.61e-9 Intelligence (multi-trait analysis); TGCT cis rs7590720 1.000 rs7590720 chr2:216898658 A/G cg12620499 chr2:216877984 MREG -0.91 -9.87 -0.66 2.65e-17 Alcohol dependence; TGCT cis rs57244997 1.000 rs73026551 chr6:162393642 A/C cg17173639 chr6:162384350 PARK2 -0.51 -5.43 -0.44 2.8e-7 Mosquito bite size; TGCT cis rs2050392 0.590 rs2065723 chr10:30720462 A/T cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs9443189 0.762 rs2647417 chr6:76435943 A/G cg01950844 chr6:76311363 SENP6 -0.69 -4.73 -0.39 6e-6 Prostate cancer; TGCT cis rs7666738 0.830 rs1426670 chr4:98923572 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs16892673 0.731 rs9458295 chr6:161937558 G/A cg23498925 chr13:52952113 THSD1 0.43 6.71 0.52 6.2e-10 Aging; TGCT cis rs1887596 0.705 rs12875211 chr13:27269900 G/A cg01312412 chr13:27282625 NA 0.3 5.34 0.43 4.23e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs7937682 0.562 rs7938620 chr11:111366844 G/A cg09085632 chr11:111637200 PPP2R1B 0.69 6.53 0.51 1.49e-9 Primary sclerosing cholangitis; TGCT cis rs9457247 0.646 rs239934 chr6:167412048 G/A cg23791538 chr6:167370224 RNASET2 -0.51 -5.08 -0.42 1.33e-6 Crohn's disease; TGCT cis rs13064411 0.735 rs6438158 chr3:113217290 C/T cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs10788264 0.569 rs3901289 chr10:124027433 T/C cg09507567 chr10:124027408 NA 0.45 6.82 0.52 3.52e-10 Total body bone mineral density; TGCT cis rs916888 0.821 rs70600 chr17:44860021 C/T cg17911788 chr17:44343683 NA -0.59 -6.13 -0.48 1.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT trans rs561341 0.941 rs4525554 chr17:30312819 T/C cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs11172134 0.508 rs1800177 chr12:57567180 G/T cg19258868 chr12:57585184 LRP1 -0.32 -6.0 -0.47 2.05e-8 Urate levels in overweight individuals; TGCT cis rs35306767 0.903 rs1341741 chr10:888073 A/G cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs1552244 1.000 rs17032299 chr3:10087638 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.89 5.58 0.45 1.45e-7 Alzheimer's disease; TGCT cis rs9916302 0.706 rs1874226 chr17:37729031 C/T cg07936489 chr17:37558343 FBXL20 0.84 6.16 0.48 9.13e-9 Glomerular filtration rate (creatinine); TGCT cis rs10782582 0.609 rs12138898 chr1:76375183 G/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.54 4.64 0.38 8.55e-6 Daytime sleep phenotypes; TGCT cis rs6835098 0.962 rs4419455 chr4:174083622 C/T cg08422745 chr4:174089978 GALNT7 0.91 10.41 0.68 1.31e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs2046867 0.628 rs61159664 chr3:72916958 C/G cg25664220 chr3:72788482 NA -0.43 -5.86 -0.47 3.9e-8 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs12477438 0.520 rs2632276 chr2:99779655 C/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.69 0.83 1.7e-33 Chronic sinus infection; TGCT cis rs362272 0.505 rs60208975 chr4:3364530 A/G cg18352616 chr4:3374830 RGS12 0.25 5.23 0.42 7.13e-7 Serum sulfate level; TGCT cis rs2760061 0.569 rs621631 chr1:228114728 A/G cg18477163 chr1:228402036 OBSCN -0.31 -6.27 -0.49 5.55e-9 Diastolic blood pressure; TGCT cis rs9790314 0.586 rs34727114 chr3:161138929 A/C cg03342759 chr3:160939853 NMD3 -0.53 -5.3 -0.43 5.21e-7 Morning vs. evening chronotype; TGCT cis rs288326 0.561 rs77227040 chr2:183894166 T/C cg09997497 chr2:183902928 NCKAP1 1.11 4.95 0.41 2.38e-6 Blood protein levels; TGCT cis rs769267 0.965 rs2074303 chr19:19381755 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.71 6.36 0.5 3.53e-9 Tonsillectomy; TGCT cis rs6866344 0.697 rs58549512 chr5:178133204 C/T cg03877680 chr5:178157825 ZNF354A 0.75 6.1 0.48 1.25e-8 Neutrophil percentage of white cells; TGCT cis rs79149102 0.579 rs7179097 chr15:75279240 T/G cg09165964 chr15:75287851 SCAMP5 -1.06 -5.96 -0.47 2.39e-8 Lung cancer; TGCT cis rs13217239 0.585 rs114919438 chr6:26963792 T/C cg05738196 chr6:26577821 NA -0.54 -5.21 -0.42 7.65e-7 Schizophrenia; TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs7027203 0.797 rs4744294 chr9:96612114 C/G cg14396892 chr9:96623032 NA -0.26 -5.47 -0.44 2.35e-7 DNA methylation (variation); TGCT cis rs9926296 0.618 rs8058179 chr16:89846987 C/T cg08627397 chr16:89984028 MC1R 0.29 4.47 0.37 1.73e-5 Vitiligo; TGCT cis rs4750440 0.637 rs2457859 chr10:14032099 T/G cg05755354 chr10:14372596 FRMD4A 0.3 4.77 0.39 5.1e-6 Adiponectin levels; TGCT cis rs10791097 0.694 rs876641 chr11:130752040 A/C cg12179176 chr11:130786555 SNX19 0.82 10.15 0.67 5.45e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs9611565 0.649 rs2064189 chr22:42127999 A/G cg03806693 chr22:41940476 POLR3H 0.97 9.86 0.66 2.81e-17 Vitiligo; TGCT trans rs7819412 0.745 rs7017567 chr8:10933699 T/A cg15556689 chr8:8085844 FLJ10661 -0.81 -7.77 -0.57 2.53e-12 Triglycerides; TGCT cis rs7666738 0.830 rs921523 chr4:98841659 C/T cg05340658 chr4:99064831 C4orf37 0.45 5.01 0.41 1.87e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs6934467 chr6:146410529 G/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.56 -0.38 1.23e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769765 0.955 rs7511159 chr22:50307896 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -10.99 -0.7 4.95e-20 Schizophrenia; TGCT trans rs1814175 0.817 rs28594987 chr11:50045181 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs9788682 1.000 rs34138960 chr15:78831668 A/G cg06917634 chr15:78832804 PSMA4 -0.7 -4.86 -0.4 3.47e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs10858047 0.883 rs6537842 chr1:115204467 C/T cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs7208859 0.623 rs73269916 chr17:29096326 A/G cg13385521 chr17:29058706 SUZ12P 0.82 4.89 0.4 3e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.830 rs991168 chr4:98928293 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7412746 0.611 rs6660084 chr1:150748803 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.73 0.39 6.04e-6 Melanoma; TGCT cis rs7412746 0.611 rs11204748 chr1:150927369 G/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs6088580 0.561 rs3761147 chr20:32996689 G/T cg06115741 chr20:33292138 TP53INP2 -0.55 -4.81 -0.4 4.28e-6 Glomerular filtration rate (creatinine); TGCT cis rs6840360 0.692 rs4479686 chr4:152399324 C/T cg17479576 chr4:152424074 FAM160A1 -0.52 -5.23 -0.43 6.86e-7 Intelligence (multi-trait analysis); TGCT cis rs4820539 1.000 rs5759596 chr22:23475750 G/A cg14186256 chr22:23484241 RTDR1 0.98 12.77 0.75 2.31e-24 Bone mineral density; TGCT cis rs61990749 0.597 rs4632066 chr14:78247282 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.64 -4.5 -0.37 1.54e-5 Fibroblast growth factor basic levels; TGCT cis rs9611565 0.694 rs5758411 chr22:42079734 G/A cg06481639 chr22:41940642 POLR3H 0.58 4.95 0.41 2.34e-6 Vitiligo; TGCT cis rs840163 0.512 rs4759035 chr12:57255135 A/G cg20779414 chr12:57505882 STAT6 0.44 4.85 0.4 3.64e-6 Alzheimer's disease (survival time); TGCT cis rs1971762 0.602 rs4759283 chr12:54079243 C/T cg16917193 chr12:54089295 NA 1.37 17.65 0.85 1.25e-35 Height; TGCT cis rs2235642 1.000 rs2076438 chr16:1584618 T/C cg10465839 chr16:1584050 IFT140;TMEM204 -0.3 -5.09 -0.42 1.31e-6 Coronary artery disease; TGCT cis rs35883536 0.967 rs2297713 chr1:101092766 T/G cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.19e-5 Monocyte count; TGCT cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg05368731 chr17:41323189 NBR1 1.21 14.63 0.8 8.89e-29 Menopause (age at onset); TGCT cis rs2072499 0.966 rs2253677 chr1:156171296 C/G cg24450063 chr1:156163899 SLC25A44 -1.2 -18.21 -0.85 7.43e-37 Testicular germ cell tumor; TGCT cis rs10504229 0.863 rs75954631 chr8:58166194 C/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs632111 0.519 rs281380 chr19:49214470 A/G cg13540341 chr19:49222985 MAMSTR 0.46 6.92 0.53 2.11e-10 Serum lipase activity; TGCT cis rs7744392 0.557 rs7739752 chr6:35339035 C/T cg06087101 chr6:35551932 FKBP5 0.61 4.56 0.38 1.21e-5 Cataracts in type 2 diabetes; TGCT cis rs13118159 0.801 rs10024996 chr4:1328297 G/A cg22683308 chr4:1340831 KIAA1530 -0.63 -5.81 -0.46 4.97e-8 Longevity; TGCT cis rs1153858 1.000 rs9783731 chr15:45642884 C/T cg14582100 chr15:45693742 SPATA5L1 -0.48 -5.7 -0.46 8.17e-8 Homoarginine levels; TGCT cis rs3820928 1.000 rs10167422 chr2:227777554 G/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.73 -0.39 5.89e-6 Pulmonary function; TGCT cis rs2594989 0.943 rs4365605 chr3:11452793 G/A cg00170343 chr3:11313890 ATG7 0.67 5.12 0.42 1.13e-6 Circulating chemerin levels; TGCT cis rs5769707 0.935 rs5770594 chr22:50018497 G/A cg10356904 chr22:49881777 NA -0.22 -4.52 -0.38 1.4e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs765787 0.530 rs4775819 chr15:45525966 C/T cg24006582 chr15:45444508 DUOX1 -0.24 -5.33 -0.43 4.54e-7 Uric acid levels; TGCT cis rs9810089 0.777 rs2688601 chr3:136252601 G/A cg12473912 chr3:136751656 NA 0.35 4.79 0.4 4.67e-6 Gestational age at birth (child effect); TGCT cis rs2932538 0.922 rs6698030 chr1:113138318 G/A cg22162597 chr1:113214053 CAPZA1 0.28 5.83 0.46 4.4e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs597539 0.652 rs482172 chr11:68668437 C/A cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 8.3 0.6 1.49e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs10489525 0.599 rs11102879 chr1:115603504 C/T cg12756093 chr1:115239321 AMPD1 -0.41 -5.51 -0.44 1.96e-7 Autism; TGCT cis rs68170813 0.559 rs75672288 chr7:107031549 G/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs9467711 0.606 rs9379852 chr6:26357278 A/G cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1857353 1.000 rs12408190 chr1:75889179 G/C cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs6671200 1.000 rs6671200 chr1:95697529 A/C cg20701556 chr1:95698924 RWDD3 -0.67 -5.63 -0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs59197085 0.636 rs3734974 chr7:128461720 C/T cg00260937 chr7:128520193 KCP 0.44 4.71 0.39 6.42e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs13256369 0.802 rs12681326 chr8:8566389 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.6 0.38 1.03e-5 Obesity-related traits; TGCT cis rs1056107 0.898 rs1831118 chr9:115002832 G/C cg02332936 chr9:115140584 NA -0.25 -4.44 -0.37 1.96e-5 Colorectal cancer; TGCT cis rs77741769 0.571 rs12822123 chr12:121298644 C/T cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 15.87 0.82 1.19e-31 Prudent dietary pattern; TGCT cis rs6912958 0.559 rs451829 chr6:88041919 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.48 6.35 0.5 3.65e-9 Monocyte percentage of white cells; TGCT cis rs2153535 0.580 rs1410766 chr6:8525360 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs12497850 0.931 rs1134591 chr3:48972892 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 5.74 0.46 6.75e-8 Parkinson's disease; TGCT cis rs3771570 0.901 rs4075818 chr2:242432142 T/C cg21155796 chr2:242212141 HDLBP 0.93 6.71 0.52 6.12e-10 Prostate cancer; TGCT trans rs7819412 0.511 rs2898290 chr8:11433909 T/C cg06636001 chr8:8085503 FLJ10661 -0.79 -7.27 -0.55 3.49e-11 Triglycerides; TGCT cis rs2243480 1.000 rs4548056 chr7:65298873 A/G cg20637647 chr7:64974828 NA 0.89 4.95 0.41 2.37e-6 Diabetic kidney disease; TGCT cis rs1799899 0.572 rs8177220 chr3:133473625 A/C cg18342939 chr3:134203408 ANAPC13;CEP63 -0.55 -5.3 -0.43 5.23e-7 Alcohol consumption (transferrin glycosylation); TGCT cis rs3806843 0.897 rs2531338 chr5:140136957 A/T cg19875535 chr5:140030758 IK -0.36 -6.09 -0.48 1.32e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs67478160 0.654 rs1535097 chr14:104216649 C/T cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs68170813 0.559 rs78888729 chr7:106940957 G/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs17376456 0.597 rs11135401 chr5:93365716 G/A cg25358565 chr5:93447407 FAM172A -0.62 -5.89 -0.47 3.45e-8 Diabetic retinopathy; TGCT cis rs9926296 0.562 rs4785725 chr16:89893243 A/G cg03388025 chr16:89894329 SPIRE2 0.35 5.28 0.43 5.66e-7 Vitiligo; TGCT cis rs12935418 0.616 rs11864367 chr16:81001779 A/T cg07676361 chr16:80966860 NA -0.35 -4.56 -0.38 1.19e-5 Mean corpuscular volume; TGCT cis rs12510870 0.634 rs1590115 chr4:74389749 T/A cg05868023 chr4:75230803 EREG 0.53 4.73 0.39 6.01e-6 Iris color (b* coordinate); TGCT cis rs10791323 0.569 rs2282601 chr11:133712594 C/G cg03690763 chr11:133734501 NA -0.31 -4.82 -0.4 4.08e-6 Childhood ear infection; TGCT cis rs986417 0.901 rs4901989 chr14:61014743 G/C cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs4819052 0.851 rs13047598 chr21:46660777 G/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.02e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs35934224 0.504 rs10372 chr22:19837298 G/A cg11182965 chr22:19864308 TXNRD2 -0.36 -4.59 -0.38 1.09e-5 Glaucoma (primary open-angle); TGCT cis rs3125734 0.608 rs7094950 chr10:64019744 T/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.46 -0.37 1.84e-5 Rheumatoid arthritis; TGCT cis rs317689 0.684 rs315125 chr12:69758884 C/T cg14784868 chr12:69753453 YEATS4 0.55 4.68 0.39 7.24e-6 Response to diuretic therapy; TGCT cis rs12681287 0.517 rs68008113 chr8:87520894 C/A cg27223183 chr8:87520930 FAM82B -0.96 -7.08 -0.54 9.31e-11 Caudate activity during reward; TGCT cis rs1322512 0.920 rs1407487 chr6:152945846 T/C cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs208520 1.000 rs208520 chr6:66952828 G/T cg07460842 chr6:66804631 NA -0.85 -7.74 -0.57 3.03e-12 Exhaled nitric oxide output; TGCT cis rs10504229 0.728 rs17804750 chr8:58155751 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs1577917 0.816 rs9353349 chr6:86707725 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.65 5.21 0.42 7.61e-7 Response to antipsychotic treatment; TGCT cis rs10089 0.953 rs6875982 chr5:127529197 A/C cg19767477 chr5:127420684 SLC12A2 -0.44 -4.63 -0.38 8.98e-6 Ileal carcinoids; TGCT cis rs17826219 0.706 rs9893922 chr17:29068425 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.87 0.4 3.36e-6 Body mass index; TGCT cis rs6879260 1.000 rs7725605 chr5:179732678 T/G cg13944838 chr5:179740914 GFPT2 -0.4 -6.4 -0.5 2.96e-9 Height; TGCT cis rs2456568 0.803 rs10831142 chr11:93640781 A/G cg26875233 chr11:93583750 C11orf90 0.48 6.45 0.5 2.3e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4819052 1.000 rs733739 chr21:46666210 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.9 7.29 0.55 3.18e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2742417 0.603 rs2064062 chr3:45761115 G/C cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs4780355 0.776 rs9936459 chr16:11437779 C/T cg00044050 chr16:11439710 C16orf75 -0.73 -6.85 -0.52 3.03e-10 Crohn's disease and psoriasis; TGCT cis rs7811142 0.830 rs705866 chr7:99965285 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs1568889 1.000 rs7931847 chr11:28175245 G/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.84 8.91 0.62 5.44e-15 Bipolar disorder; TGCT cis rs9297145 0.673 rs62473003 chr7:98725660 A/G cg05967295 chr7:98741636 SMURF1 1.0 12.46 0.75 1.35e-23 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs13217239 0.646 rs12201393 chr6:26975690 C/A cg26531700 chr6:26746687 NA 0.68 6.79 0.52 4.1e-10 Schizophrenia; TGCT cis rs7618915 0.501 rs2079929 chr3:52765646 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT cis rs7027203 0.538 rs2244395 chr9:96520723 A/G cg14598338 chr9:96623480 NA -0.49 -7.04 -0.53 1.18e-10 DNA methylation (variation); TGCT cis rs597539 0.652 rs507520 chr11:68666054 C/T cg06112835 chr11:68658793 MRPL21 0.47 8.23 0.59 2.19e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9942416 0.660 rs41534344 chr5:74997832 T/C cg19683494 chr5:74908142 NA 0.57 6.37 0.5 3.33e-9 Age-related disease endophenotypes; TGCT cis rs9467773 0.595 rs2237236 chr6:26451553 A/G cg15659132 chr6:26577336 NA -0.43 -4.52 -0.38 1.45e-5 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs6848404 chr4:98946750 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6121246 0.529 rs6060291 chr20:30198043 T/G cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs9810089 0.758 rs12492510 chr3:136151631 G/T cg12473912 chr3:136751656 NA 0.36 5.1 0.42 1.22e-6 Gestational age at birth (child effect); TGCT cis rs601339 1.000 rs601339 chr12:123174743 A/G cg11919336 chr12:123188078 GPR109A 0.64 7.49 0.56 1.1e-11 Adiponectin levels; TGCT cis rs1218582 0.741 rs2335407 chr1:154843347 A/G cg16680214 chr1:154839983 KCNN3 0.43 9.51 0.65 1.94e-16 Prostate cancer; TGCT cis rs453301 0.571 rs2929456 chr8:9083416 G/A cg15556689 chr8:8085844 FLJ10661 -0.64 -6.05 -0.48 1.6e-8 Joint mobility (Beighton score); TGCT cis rs873946 0.590 rs7071777 chr10:134559976 T/A cg27286337 chr10:134555280 INPP5A 0.39 4.79 0.39 4.75e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9393777 0.513 rs9379907 chr6:26654318 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs7095607 0.935 rs12415105 chr10:69958631 G/A cg18986048 chr10:69913749 MYPN 0.45 4.85 0.4 3.56e-6 Lung function (FVC); TGCT cis rs2760061 0.717 rs708117 chr1:228199902 G/A cg02753203 chr1:228287806 NA 0.32 6.14 0.48 1e-8 Diastolic blood pressure; TGCT cis rs2019216 0.521 rs2175657 chr17:21908494 T/G cg22648282 chr17:21454238 C17orf51 -0.61 -6.04 -0.48 1.69e-8 Pelvic organ prolapse; TGCT cis rs7714584 1.000 rs11747270 chr5:150258867 C/T cg22134413 chr5:150180641 NA -0.78 -6.12 -0.48 1.16e-8 Crohn's disease; TGCT cis rs2652822 0.509 rs8468 chr15:63434110 C/T cg12855773 chr15:63363890 TPM1 -0.19 -5.16 -0.42 9.31e-7 Metabolic traits; TGCT trans rs11722228 0.549 rs2241488 chr4:10101131 T/C cg26043149 chr18:55253948 FECH 1.16 11.02 0.7 4.14e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs9972944 1.000 rs9972944 chr17:63771079 A/G cg07283582 chr17:63770753 CCDC46 0.28 5.89 0.47 3.36e-8 Total body bone mineral density; TGCT cis rs9325144 0.723 rs1586373 chr12:39181582 G/A cg10518543 chr12:38710700 ALG10B -0.5 -4.65 -0.39 8.28e-6 Morning vs. evening chronotype; TGCT cis rs8177253 0.665 rs9869535 chr3:133451581 G/A cg01448562 chr3:133502909 NA -0.26 -5.06 -0.41 1.49e-6 Iron status biomarkers; TGCT cis rs10507380 0.824 rs9507880 chr13:27915667 T/A cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs7208859 0.673 rs79541516 chr17:29240583 C/T cg14008862 chr17:28927542 LRRC37B2 0.72 4.62 0.38 9.31e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1023500 1.000 rs6002554 chr22:42339095 T/C cg04692870 chr22:42525206 CYP2D6 -0.35 -5.2 -0.42 7.83e-7 Schizophrenia; TGCT cis rs11098499 0.863 rs1155576 chr4:120450159 A/C cg09307838 chr4:120376055 NA 0.71 6.96 0.53 1.71e-10 Corneal astigmatism; TGCT cis rs3733585 0.673 rs7434391 chr4:9967682 C/G cg11266682 chr4:10021025 SLC2A9 -0.59 -7.85 -0.58 1.7e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2594989 1.000 rs2594986 chr3:11330964 G/A cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs6088580 0.634 rs6088502 chr20:33037644 A/T cg08999081 chr20:33150536 PIGU 0.28 5.52 0.44 1.89e-7 Glomerular filtration rate (creatinine); TGCT cis rs1757171 0.534 rs2797793 chr6:37477262 C/T cg08126542 chr6:37504118 NA 0.4 5.71 0.46 7.9e-8 Cognitive performance; TGCT cis rs10782582 0.609 rs56159153 chr1:76353498 T/G cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT trans rs1814175 0.817 rs7929173 chr11:49944007 T/C cg15704280 chr7:45808275 SEPT13 -0.7 -7.78 -0.57 2.45e-12 Height; TGCT cis rs1577917 1.000 rs35797755 chr6:86706554 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs7678296 0.649 rs77896458 chr4:37237843 A/G cg18431856 chr4:37245254 KIAA1239 0.68 4.47 0.37 1.74e-5 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs28386778 0.897 rs11654841 chr17:61838259 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.53 -5.21 -0.42 7.55e-7 Prudent dietary pattern; TGCT cis rs35146811 0.961 rs1880949 chr7:99722266 A/C cg22906224 chr7:99728672 NA -0.55 -5.05 -0.41 1.52e-6 Coronary artery disease; TGCT cis rs17376456 1.000 rs17376207 chr5:93545524 C/T cg25358565 chr5:93447407 FAM172A -0.93 -7.58 -0.56 6.91e-12 Diabetic retinopathy; TGCT cis rs853679 0.517 rs16893666 chr6:28054707 C/T cg12963246 chr6:28129442 ZNF389 -0.5 -5.05 -0.41 1.53e-6 Depression; TGCT cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs4808199 0.948 rs757000 chr19:19448301 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.33 0.43 4.49e-7 Nonalcoholic fatty liver disease; TGCT trans rs12339966 0.653 rs10733232 chr9:11285316 G/T cg07173112 chr1:1114698 TTLL10 -0.34 -6.68 -0.51 7.34e-10 Systolic blood pressure; TGCT cis rs10744422 1.000 rs10744422 chr12:123336789 T/C cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs10883723 0.810 rs7090276 chr10:104281239 G/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2692947 0.644 rs1168975 chr2:96814075 G/A cg22654517 chr2:96458247 NA 0.23 4.86 0.4 3.42e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs9611565 0.512 rs4822052 chr22:42193741 G/A cg17554472 chr22:41940697 POLR3H -0.43 -4.62 -0.38 9.4e-6 Vitiligo; TGCT cis rs17767294 0.708 rs72848772 chr6:27920948 C/T cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs6964587 0.967 rs10231496 chr7:91741132 T/C cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.21e-5 Breast cancer; TGCT cis rs17253792 0.822 rs78988988 chr14:56152404 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs10779751 0.960 rs11121712 chr1:11320329 G/C cg08854313 chr1:11322531 MTOR 0.94 10.47 0.69 8.87e-19 Body mass index; TGCT cis rs6988636 0.792 rs62521807 chr8:124163621 T/C cg23067535 chr8:124195133 FAM83A -0.35 -4.75 -0.39 5.61e-6 Urinary uromodulin levels; TGCT cis rs13256369 1.000 rs12547721 chr8:8570671 C/T cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs7586879 0.828 rs1865688 chr2:25108245 C/G cg01884057 chr2:25150051 NA 0.26 4.58 0.38 1.14e-5 Body mass index; TGCT cis rs62244186 0.715 rs10212378 chr3:44667286 C/G cg09333631 chr3:44802604 KIF15;KIAA1143 -0.41 -4.63 -0.38 8.91e-6 Depressive symptoms; TGCT cis rs2046867 0.954 rs74559336 chr3:72780501 T/C cg25664220 chr3:72788482 NA -0.56 -6.91 -0.53 2.3e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs911263 0.961 rs28498223 chr14:68728425 C/T cg18825221 chr14:68749962 RAD51L1 -0.3 -5.8 -0.46 5.2100000000000003e-08 Primary biliary cholangitis; TGCT cis rs9942416 0.660 rs34905687 chr5:74997736 A/G cg07671805 chr5:74907694 NA 0.44 4.47 0.37 1.73e-5 Age-related disease endophenotypes; TGCT cis rs7264396 0.635 rs6060719 chr20:34546013 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs6032067 0.561 rs2741502 chr20:43936265 C/T cg16667508 chr20:43936853 MATN4;RBPJL -0.41 -6.4 -0.5 2.92e-9 Blood protein levels; TGCT cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg05665937 chr4:1216051 CTBP1 0.25 4.68 0.39 7.33e-6 Obesity-related traits; TGCT cis rs597539 0.652 rs636049 chr11:68667198 A/C cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 8.74e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg07424592 chr7:64974309 NA 1.34 8.17 0.59 3.1e-13 Diabetic kidney disease; TGCT cis rs9911578 0.785 rs10853008 chr17:56993407 T/C cg12560992 chr17:57184187 TRIM37 -0.8 -8.13 -0.59 3.72e-13 Intelligence (multi-trait analysis); TGCT cis rs7954584 0.813 rs11043288 chr12:122451187 C/T cg22618164 chr12:122356400 WDR66 -0.53 -5.04 -0.41 1.61e-6 Mean corpuscular volume; TGCT cis rs13102973 0.965 rs13142779 chr4:135872841 G/T cg14419869 chr4:135874104 NA 0.24 4.46 0.37 1.83e-5 Subjective well-being; TGCT trans rs2727020 0.823 rs7102374 chr11:49261795 G/A cg03929089 chr4:120376271 NA 0.73 8.12 0.59 4e-13 Coronary artery disease; TGCT cis rs11673344 0.504 rs7258360 chr19:37605917 C/T cg08039142 chr19:36980659 ZNF566 0.53 4.74 0.39 5.87e-6 Obesity-related traits; TGCT cis rs35883536 0.900 rs7520474 chr1:101091376 T/C cg06223162 chr1:101003688 GPR88 -0.3 -4.99 -0.41 2e-6 Monocyte count; TGCT cis rs7119 0.635 rs867916 chr15:77882860 A/G cg27398640 chr15:77910606 LINGO1 0.31 6.17 0.48 9.04e-9 Type 2 diabetes; TGCT trans rs1864729 1.000 rs2853312 chr8:98281319 T/C cg08679828 chr8:102218111 ZNF706 -1.07 -7.43 -0.56 1.55e-11 Estradiol plasma levels (breast cancer); TGCT cis rs62244186 0.683 rs6766334 chr3:44567065 T/C cg02073558 chr3:44770973 ZNF501 0.62 5.96 0.47 2.41e-8 Depressive symptoms; TGCT cis rs10865541 0.545 rs10176868 chr2:3383662 C/T cg01472464 chr2:3383078 TTC15;TSSC1 0.24 4.5 0.37 1.55e-5 Obesity-related traits; TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg00024416 chr22:24240387 NA 0.26 5.26 0.43 6.21e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8177253 0.829 rs6794945 chr3:133518463 A/G cg11941060 chr3:133502564 NA 0.3 6.55 0.51 1.4e-9 Iron status biomarkers; TGCT cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg05985448 chr10:134359359 INPP5A 0.23 4.96 0.41 2.3e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs524281 0.861 rs11227410 chr11:65873396 G/C cg00563793 chr11:65837595 PACS1 0.55 4.62 0.38 9.44e-6 Electroencephalogram traits; TGCT trans rs2727020 0.567 rs1164687 chr11:49290669 G/A cg15704280 chr7:45808275 SEPT13 0.72 7.71 0.57 3.47e-12 Coronary artery disease; TGCT cis rs631288 0.793 rs6681716 chr1:146707824 A/C cg25205988 chr1:146714368 CHD1L 1.17 6.25 0.49 6.09e-9 PR interval in Tripanosoma cruzi seropositivity; TGCT cis rs67311347 1.000 rs73078169 chr3:40483798 G/A cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs4665809 0.838 rs7565843 chr2:26292912 G/C cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs11098499 0.954 rs17046116 chr4:120387259 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs7267979 1.000 rs4815408 chr20:25346678 C/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2243480 1.000 rs2465120 chr7:65620974 C/G cg07424592 chr7:64974309 NA 1.27 7.84 0.58 1.8e-12 Diabetic kidney disease; TGCT cis rs6977660 0.507 rs4721822 chr7:19771693 T/C cg07541023 chr7:19748670 TWISTNB 0.98 6.43 0.5 2.48e-9 Thyroid stimulating hormone; TGCT cis rs921968 0.540 rs10190250 chr2:219457731 C/T cg02176678 chr2:219576539 TTLL4 -0.49 -6.93 -0.53 1.99e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs9399135 0.967 rs12526055 chr6:135325918 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.83 0.4 3.94e-6 Red blood cell count; TGCT cis rs6061231 1.000 rs6061231 chr20:60956917 C/A cg24112000 chr20:60950667 NA -0.36 -5.12 -0.42 1.11e-6 Colorectal cancer; TGCT cis rs10501293 0.917 rs10768914 chr11:43102263 G/A cg03447554 chr11:43094025 NA -0.47 -6.58 -0.51 1.2e-9 Cognitive performance; TGCT cis rs1218582 0.774 rs11264284 chr1:154875793 C/T cg06221963 chr1:154839813 KCNN3 -0.79 -15.15 -0.81 5.4e-30 Prostate cancer; TGCT cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg16405210 chr4:1374714 KIAA1530 -0.26 -4.59 -0.38 1.06e-5 Longevity; TGCT cis rs910316 0.875 rs12588099 chr14:75594462 A/T cg23033748 chr14:75592666 NEK9 0.29 4.9 0.4 2.94e-6 Height; TGCT cis rs35934224 0.891 rs8141451 chr22:19870036 C/G cg11182965 chr22:19864308 TXNRD2 -0.38 -5.34 -0.43 4.3e-7 Glaucoma (primary open-angle); TGCT cis rs1801251 1.000 rs7592717 chr2:233577038 G/A cg08000102 chr2:233561755 GIGYF2 0.66 6.84 0.52 3.29e-10 Coronary artery disease; TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs2486288 0.656 rs11629858 chr15:45547114 T/C cg14582100 chr15:45693742 SPATA5L1 -0.44 -5.02 -0.41 1.78e-6 Glomerular filtration rate; TGCT cis rs6740322 0.748 rs6756625 chr2:43489313 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.37 6.46 0.5 2.18e-9 Coronary artery disease; TGCT cis rs769267 0.931 rs15622 chr19:19468734 G/A cg02546618 chr19:19431379 KIAA0892;SF4 -0.63 -5.13 -0.42 1.07e-6 Tonsillectomy; TGCT cis rs4986172 0.726 rs12051846 chr17:43226887 A/G cg10701640 chr17:43249399 NA 0.55 6.58 0.51 1.18e-9 Height; TGCT cis rs7618915 0.547 rs12486847 chr3:52691112 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs7914558 1.000 rs10509757 chr10:104752960 C/T cg15744005 chr10:104629667 AS3MT -0.41 -5.06 -0.41 1.47e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs72845660 0.513 rs72845694 chr10:104169733 C/T cg26089160 chr10:104170217 PSD 0.51 5.08 0.41 1.37e-6 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.841 rs115851302 chr4:119776504 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs6666258 0.924 rs34292822 chr1:154812400 G/C cg06418219 chr1:154948305 SHC1;CKS1B 0.65 5.22 0.42 7.23e-7 Atrial fibrillation; TGCT cis rs1865760 0.508 rs9379820 chr6:26049924 T/C cg16482183 chr6:26056742 HIST1H1C 0.58 4.98 0.41 2.12e-6 Height; TGCT cis rs1799949 0.896 rs8176086 chr17:41274778 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs9894429 0.646 rs7217415 chr17:79618252 G/A cg18240062 chr17:79603768 NPLOC4 0.54 4.63 0.38 9.22e-6 Eye color traits; TGCT cis rs5769765 0.908 rs2319464 chr22:50265777 A/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs9911578 1.000 rs437732 chr17:56675861 A/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.3 -0.49 4.84e-9 Intelligence (multi-trait analysis); TGCT cis rs4665809 0.556 rs6730311 chr2:26419474 C/T cg25036284 chr2:26402008 FAM59B -0.62 -5.06 -0.41 1.47e-6 Gut microbiome composition (summer); TGCT cis rs2440129 0.611 rs434473 chr17:6904934 A/G cg03404566 chr17:6899310 ALOX12 -0.43 -4.85 -0.4 3.56e-6 Tonsillectomy; TGCT trans rs1496653 0.602 rs35657558 chr3:23384808 T/C cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs7772486 0.875 rs56181683 chr6:146286620 A/G cg23711669 chr6:146136114 FBXO30 -0.84 -9.06 -0.63 2.3e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7088591 0.614 rs16911550 chr10:59758506 T/C cg07264682 chr10:60082823 NA 0.35 4.52 0.38 1.42e-5 Blood pressure; TGCT cis rs9322193 0.923 rs9767105 chr6:149980727 A/G cg13206674 chr6:150067644 NUP43 0.52 4.62 0.38 9.53e-6 Lung cancer; TGCT cis rs4242434 0.672 rs3758042 chr8:22486951 T/C cg03733263 chr8:22462867 KIAA1967 0.98 13.14 0.76 2.97e-25 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9297145 1.000 rs9297145 chr7:98759117 A/C cg05967295 chr7:98741636 SMURF1 1.02 16.5 0.83 4.56e-33 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg10819733 chr22:24237672 NA -0.29 -4.84 -0.4 3.85e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1878931 0.501 rs4785934 chr16:3419934 G/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 7.12 0.54 7.59e-11 Body mass index (adult); TGCT cis rs6671200 0.573 rs3820345 chr1:95713175 C/T cg26537280 chr1:95699037 RWDD3 -0.51 -4.9 -0.4 2.94e-6 Stearic acid (18:0) levels; TGCT cis rs4665809 0.549 rs13001722 chr2:26521530 T/C cg04944784 chr2:26401820 FAM59B 0.8 5.67 0.45 9.45e-8 Gut microbiome composition (summer); TGCT cis rs2836974 0.644 rs11088472 chr21:40699376 A/C cg11644478 chr21:40555479 PSMG1 -0.53 -4.55 -0.38 1.28e-5 Cognitive function; TGCT cis rs9379850 0.527 rs9393704 chr6:26358775 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Intelligence (multi-trait analysis); TGCT trans rs3780486 0.522 rs10217770 chr9:33146393 C/A cg04842962 chr6:43655489 MRPS18A 0.78 8.41 0.6 8.28e-14 IgG glycosylation; TGCT cis rs1784581 0.500 rs9355379 chr6:162421466 C/T cg17173639 chr6:162384350 PARK2 0.37 4.77 0.39 5.16e-6 Itch intensity from mosquito bite; TGCT cis rs7909074 0.966 rs4948645 chr10:45391481 A/G cg04218760 chr10:45406644 TMEM72 -0.26 -5.23 -0.43 6.89e-7 Mean corpuscular volume; TGCT cis rs7267979 1.000 rs2474777 chr20:25272633 A/G cg16686733 chr20:25566563 NINL 0.59 6.03 0.48 1.71e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9818758 0.607 rs55873331 chr3:49597055 C/T cg07636037 chr3:49044803 WDR6 -0.98 -4.72 -0.39 6.18e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs4851254 0.920 rs11123808 chr2:100750750 A/C cg04109781 chr2:100722022 AFF3 0.45 4.8 0.4 4.51e-6 Intelligence (multi-trait analysis); TGCT cis rs2239547 0.603 rs9870898 chr3:53092375 A/G cg10802521 chr3:52805072 NEK4 -0.57 -5.22 -0.42 7.38e-7 Schizophrenia; TGCT trans rs941408 1.000 rs1736176 chr19:2790394 G/A cg19676328 chr12:49525230 TUBA1B -0.68 -6.62 -0.51 9.9e-10 Total cholesterol levels; TGCT cis rs6854137 0.524 rs9991075 chr4:169701090 A/G cg20607169 chr4:169750834 PALLD 0.21 4.45 0.37 1.91e-5 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs11585357 0.895 rs72633814 chr1:17626456 T/C cg08277548 chr1:17600880 PADI3 -0.95 -9.6 -0.65 1.15e-16 Hair shape; TGCT cis rs7120118 0.517 rs12221497 chr11:47280653 G/A cg13308137 chr11:47528955 CUGBP1 0.33 5.19 0.42 8.16e-7 HDL cholesterol; TGCT cis rs62244186 0.627 rs3935212 chr3:44460954 G/A cg02073558 chr3:44770973 ZNF501 0.59 5.75 0.46 6.53e-8 Depressive symptoms; TGCT cis rs938554 0.513 rs4529048 chr4:9997112 G/T cg02734326 chr4:10020555 SLC2A9 0.58 4.77 0.39 5.11e-6 Blood metabolite levels; TGCT cis rs7811142 0.830 rs6955367 chr7:99961194 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -8.51 -0.61 4.86e-14 Platelet count; TGCT cis rs17384381 0.906 rs2300639 chr1:85823676 T/A cg16011679 chr1:85725395 C1orf52 0.85 6.6 0.51 1.1e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs17376456 0.569 rs68122392 chr5:93077807 A/T cg25358565 chr5:93447407 FAM172A 0.74 6.42 0.5 2.66e-9 Diabetic retinopathy; TGCT cis rs4919044 0.808 rs835271 chr10:94791678 C/T cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs10875746 0.859 rs4760680 chr12:48466697 G/T cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs13118159 0.742 rs7679860 chr4:1333987 C/T cg20887711 chr4:1340912 KIAA1530 0.54 4.76 0.39 5.33e-6 Longevity; TGCT cis rs700590 0.723 rs304160 chr5:88135462 T/C cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.22e-7 Educational attainment (years of education); TGCT cis rs7586879 0.964 rs11688665 chr2:25121168 G/T cg01884057 chr2:25150051 NA 0.27 4.84 0.4 3.75e-6 Body mass index; TGCT cis rs4746818 1.000 rs7071904 chr10:70903005 C/T cg04149295 chr10:70884716 VPS26A 0.79 5.39 0.44 3.47e-7 Left atrial antero-posterior diameter; TGCT cis rs10114408 0.959 rs1933673 chr9:96655010 A/T cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 7e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2404602 0.735 rs4886798 chr15:76673226 A/G cg26408565 chr15:76604113 ETFA -0.39 -4.53 -0.38 1.35e-5 Blood metabolite levels; TGCT cis rs9611565 0.500 rs10775759 chr22:42088158 T/C cg03806693 chr22:41940476 POLR3H 1.06 11.74 0.73 7.15e-22 Vitiligo; TGCT cis rs3087591 0.708 rs2285894 chr17:29654876 T/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.46 0.44 2.45e-7 Hip circumference; TGCT cis rs4851254 0.660 rs4851244 chr2:100671449 C/T cg07810366 chr2:100720526 AFF3 0.49 5.22 0.42 7.36e-7 Intelligence (multi-trait analysis); TGCT cis rs11690462 0.963 rs17529423 chr2:26583506 A/C cg11525280 chr2:26624667 C2orf39 0.35 4.47 0.37 1.73e-5 Coronary artery disease; TGCT cis rs4704846 1.000 rs919747 chr5:156531330 A/G cg12943317 chr5:156479607 HAVCR1 -0.34 -4.75 -0.39 5.43e-6 Blood protein levels; TGCT cis rs17270561 0.514 rs10946805 chr6:26077891 C/T cg17042849 chr6:26104293 HIST1H4C -0.85 -5.98 -0.47 2.2e-8 Iron status biomarkers; TGCT cis rs4654899 0.965 rs2873424 chr1:21500701 C/A cg01072550 chr1:21505969 NA -0.51 -8.23 -0.59 2.18e-13 Superior frontal gyrus grey matter volume; TGCT cis rs769267 0.930 rs2315022 chr19:19413381 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.7 6.33 0.49 4.02e-9 Tonsillectomy; TGCT cis rs2836974 0.831 rs2836964 chr21:40631006 T/C cg11890956 chr21:40555474 PSMG1 1.09 11.98 0.73 1.95e-22 Cognitive function; TGCT cis rs9419702 0.526 rs9419637 chr10:133548059 T/C cg23460707 chr10:133558971 NA 0.44 4.9 0.4 2.96e-6 Survival in rectal cancer; TGCT cis rs28595532 0.920 rs114683212 chr4:119760209 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4690686 0.500 rs7667671 chr4:177275599 T/C cg17059388 chr4:177262070 NA 0.29 4.59 0.38 1.09e-5 Essential tremor; TGCT cis rs66561647 0.719 rs7812386 chr8:128937609 C/A cg11792826 chr8:129160931 MIR1208 0.22 5.15 0.42 1.01e-6 Hemoglobin concentration; TGCT cis rs9611565 0.512 rs2899349 chr22:42164660 T/C cg06481639 chr22:41940642 POLR3H 0.69 6.05 0.48 1.59e-8 Vitiligo; TGCT cis rs9381040 0.626 rs2272986 chr6:41037778 C/T cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs2463822 0.925 rs2513075 chr11:62102408 C/T cg06239285 chr11:62104954 ASRGL1 0.93 6.71 0.52 6.27e-10 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9462846 0.691 rs9462853 chr6:42910666 T/C cg13397359 chr6:42928475 GNMT 0.58 4.52 0.38 1.41e-5 Blood protein levels; TGCT cis rs4499344 0.555 rs7250741 chr19:33033231 T/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.68 -5.73 -0.46 7.27e-8 Mean platelet volume; TGCT cis rs9486719 0.843 rs2499792 chr6:96846264 A/C cg06623918 chr6:96969491 KIAA0776 0.93 7.08 0.54 9.59e-11 Migraine;Coronary artery disease; TGCT cis rs6912958 0.781 rs9450738 chr6:88267314 A/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg25036284 chr2:26402008 FAM59B -0.65 -5.27 -0.43 5.77e-7 Gut microbiome composition (summer); TGCT cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg17554472 chr22:41940697 POLR3H 0.43 4.56 0.38 1.22e-5 Vitiligo; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg18538332 chr22:24372958 LOC391322 -0.85 -9.96 -0.67 1.61e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs17164851 0.636 rs17164847 chr7:130003458 A/G cg01390574 chr7:129425451 NA -0.65 -4.47 -0.37 1.74e-5 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs5750830 0.649 rs5750814 chr22:39797987 T/C cg11247378 chr22:39784982 NA -0.74 -10.33 -0.68 1.98e-18 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs9733 0.536 rs10888385 chr1:150574302 T/C cg13175981 chr1:150552382 MCL1 0.55 6.33 0.49 4.15e-9 Tonsillectomy; TGCT cis rs4808199 0.947 rs10401193 chr19:19591066 A/G cg03709012 chr19:19516395 GATAD2A 1.0 7.85 0.58 1.69e-12 Nonalcoholic fatty liver disease; TGCT cis rs9916302 0.904 rs8079355 chr17:37473018 G/A cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs17376456 0.542 rs1982439 chr5:93160560 C/G cg21475434 chr5:93447410 FAM172A -0.63 -4.96 -0.41 2.23e-6 Diabetic retinopathy; TGCT cis rs1878931 0.696 rs35175748 chr16:3445427 C/G cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 12.26 0.74 4.06e-23 Body mass index (adult); TGCT trans rs57221529 0.766 rs72704799 chr5:551457 C/G cg11887960 chr12:57824829 NA 1.12 8.48 0.61 5.72e-14 Lung disease severity in cystic fibrosis; TGCT cis rs1008375 1.000 rs2315561 chr4:17679695 C/T cg16339924 chr4:17578868 LAP3 0.56 4.8 0.4 4.43e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1799949 1.000 rs1960605 chr17:41305397 C/T cg05368731 chr17:41323189 NBR1 1.2 14.48 0.79 1.98e-28 Menopause (age at onset); TGCT cis rs2180341 0.883 rs7760748 chr6:127690062 C/T cg24812749 chr6:127587940 RNF146 0.92 7.43 0.55 1.55e-11 Breast cancer; TGCT cis rs350251 0.899 rs350274 chr16:12233259 G/C cg02910054 chr16:12241554 SNX29 0.33 4.57 0.38 1.18e-5 Intelligence (multi-trait analysis); TGCT cis rs7584330 0.868 rs13408361 chr2:238382899 A/G cg14458575 chr2:238380390 NA 0.5 7.89 0.58 1.35e-12 Prostate cancer; TGCT cis rs1862618 0.573 rs832532 chr5:56221938 T/C cg12311346 chr5:56204834 C5orf35 -0.82 -7.71 -0.57 3.54e-12 Initial pursuit acceleration; TGCT cis rs2576037 0.566 rs2437854 chr18:44557613 T/C cg23302884 chr18:44338147 ST8SIA5 0.43 5.02 0.41 1.77e-6 Personality dimensions; TGCT cis rs12510870 0.566 rs28696705 chr4:74426954 C/G cg05868023 chr4:75230803 EREG 0.54 4.89 0.4 3.07e-6 Iris color (b* coordinate); TGCT cis rs7927771 0.770 rs11039203 chr11:47384597 A/G cg21462715 chr11:47870315 NUP160 0.57 4.63 0.38 9.08e-6 Subjective well-being; TGCT cis rs2797160 1.000 rs9401843 chr6:126004124 T/C cg05901451 chr6:126070800 HEY2 -0.74 -6.3 -0.49 4.62e-9 Endometrial cancer; TGCT cis rs950880 0.560 rs12712141 chr2:102953067 A/G cg09003973 chr2:102972529 NA -0.51 -4.5 -0.37 1.54e-5 Serum protein levels (sST2); TGCT cis rs73110464 0.505 rs2638503 chr12:53307369 C/G cg05393297 chr12:53359155 NA -0.43 -4.87 -0.4 3.36e-6 Cancer (pleiotropy); TGCT cis rs2735413 0.564 rs78898310 chr16:78115510 T/C cg09132178 chr16:78079569 NA 0.37 4.7 0.39 6.84e-6 Systolic blood pressure (alcohol consumption interaction); TGCT cis rs2440129 0.611 rs2292352 chr17:6902887 A/G cg03407747 chr17:6899364 ALOX12 0.52 5.67 0.45 9.41e-8 Tonsillectomy; TGCT cis rs1153858 1.000 rs1365610 chr15:45694610 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7208859 0.673 rs11652409 chr17:29182707 T/A cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4808199 1.000 rs7258508 chr19:19475469 T/C cg03709012 chr19:19516395 GATAD2A 1.0 8.01 0.58 7.11e-13 Nonalcoholic fatty liver disease; TGCT cis rs10782582 0.609 rs80059220 chr1:76279112 G/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs4819852 0.958 rs2238787 chr22:19976406 G/A cg07821417 chr22:19972146 ARVCF 0.19 4.79 0.4 4.7e-6 Pulse pressure; TGCT cis rs9911578 0.967 rs6503890 chr17:57064167 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.14 -0.48 1.03e-8 Intelligence (multi-trait analysis); TGCT cis rs7010267 0.773 rs72680380 chr8:119932741 T/A cg17171407 chr8:119960777 TNFRSF11B -0.29 -5.06 -0.41 1.44e-6 Total body bone mineral density (age 45-60); TGCT cis rs2479724 0.792 rs7739064 chr6:41834037 C/A cg08135965 chr6:41755394 TOMM6 0.46 4.48 0.37 1.7e-5 Menarche (age at onset); TGCT cis rs1420338 0.967 rs2192874 chr7:34144916 G/A cg01275685 chr7:34179230 BMPER -0.25 -4.69 -0.39 7.03e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs1205863 1.000 rs1205891 chr6:11948621 C/A cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs6074578 0.535 rs6077293 chr20:138620 A/C cg16931068 chr20:139680 DEFB127 0.27 4.47 0.37 1.75e-5 Hirschsprung disease; TGCT cis rs6598955 0.671 rs11247910 chr1:26645666 G/A cg04990556 chr1:26633338 UBXN11 0.64 4.55 0.38 1.27e-5 Obesity-related traits; TGCT cis rs13064411 0.735 rs7636128 chr3:113133701 A/T cg10517650 chr3:113235015 CCDC52 -0.35 -4.69 -0.39 7.18e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs6598955 0.724 rs12757113 chr1:26597144 C/T cg04990556 chr1:26633338 UBXN11 -0.87 -10.54 -0.69 6.11e-19 Obesity-related traits; TGCT cis rs2797160 1.000 rs77678056 chr6:126019738 A/G cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 4.85e-9 Endometrial cancer; TGCT cis rs1532993 0.518 rs1983166 chr4:98583178 A/G cg05340658 chr4:99064831 C4orf37 0.41 4.77 0.39 5.05e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs155076 1.000 rs261369 chr13:21868420 C/A cg11317459 chr13:21872234 NA -1.29 -11.56 -0.72 2.03e-21 White matter hyperintensity burden; TGCT cis rs4819052 0.840 rs914217 chr21:46698299 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.99 8.08 0.59 4.92e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1372520 0.766 rs2583961 chr4:90779758 A/G cg20003494 chr4:90757398 SNCA -0.65 -5.22 -0.42 7.45e-7 Neuroticism; TGCT cis rs492146 0.935 rs316139 chr6:52846372 G/T cg06706454 chr6:52930286 FBXO9 -0.47 -4.54 -0.38 1.32e-5 Epilepsy (remission after treatment); TGCT cis rs7208859 0.673 rs73263981 chr17:28920502 A/G cg04154034 chr17:28927549 LRRC37B2 0.79 4.8 0.4 4.54e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9394841 0.810 rs3218097 chr6:41905275 G/A cg08135965 chr6:41755394 TOMM6 0.56 5.35 0.43 4.05e-7 Mean corpuscular hemoglobin;Red cell distribution width; TGCT trans rs208520 1.000 rs12189683 chr6:66977716 A/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.83 -7.46 -0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs2859741 1.000 rs2859741 chr1:37509352 C/T cg09363841 chr1:37513479 NA -0.19 -4.49 -0.37 1.63e-5 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs763121 0.819 rs138700 chr22:39129999 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.17 0.54 6e-11 Menopause (age at onset); TGCT cis rs7236492 0.748 rs11664153 chr18:77195813 G/A cg15644404 chr18:77186268 NFATC1 -0.35 -4.67 -0.39 7.83e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs6089584 0.888 rs6089623 chr20:60615759 A/G cg13665807 chr20:60559372 TAF4 -0.46 -5.0 -0.41 1.92e-6 Body mass index; TGCT cis rs10986311 0.775 rs4574 chr9:127177161 A/G cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.64 -0.38 8.78e-6 Vitiligo; TGCT cis rs9393692 0.905 rs9358919 chr6:26287862 C/T cg00631329 chr6:26305371 NA -0.41 -6.08 -0.48 1.34e-8 Educational attainment; TGCT cis rs10791323 0.569 rs2156679 chr11:133742304 C/T cg15485101 chr11:133734466 NA 0.37 5.42 0.44 3e-7 Childhood ear infection; TGCT cis rs4689592 0.546 rs2359012 chr4:7066053 A/C cg02503808 chr4:7069936 GRPEL1 0.98 9.23 0.64 9.22e-16 Monocyte percentage of white cells; TGCT cis rs72945132 0.678 rs12786421 chr11:70235314 G/C cg00319359 chr11:70116639 PPFIA1 0.99 7.17 0.54 5.79e-11 Coronary artery disease; TGCT cis rs6964587 1.000 rs756647 chr7:91586389 A/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs1865760 0.929 rs1816546 chr6:25938252 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.66 6.2 0.49 7.8e-9 Height; TGCT cis rs813218 0.584 rs793469 chr3:99537305 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.47 5.29 0.43 5.28e-7 Orofacial clefts; TGCT cis rs9952991 1.000 rs9952991 chr18:12780464 G/A cg24737193 chr18:12778029 NA 0.51 5.73 0.46 7.31e-8 Inflammatory skin disease; TGCT cis rs9916302 0.904 rs4795359 chr17:37573146 C/T cg07936489 chr17:37558343 FBXL20 -0.65 -4.98 -0.41 2.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs73110464 0.505 rs2682296 chr12:53308265 G/A cg16329197 chr12:53359506 NA -0.32 -4.78 -0.39 4.86e-6 Cancer (pleiotropy); TGCT cis rs2243480 0.901 rs35087093 chr7:65405208 C/T cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs1799949 1.000 rs8176273 chr17:41211653 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 4.92 0.4 2.75e-6 Menopause (age at onset); TGCT trans rs1496653 0.602 rs71322174 chr3:23409907 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs12477438 0.798 rs6712338 chr2:99585457 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs7845219 0.544 rs9643350 chr8:95917276 C/A cg16049864 chr8:95962084 TP53INP1 -0.46 -5.12 -0.42 1.11e-6 Type 2 diabetes; TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg11494091 chr17:61959527 GH2 0.61 14.83 0.8 2.95e-29 Prudent dietary pattern; TGCT cis rs10057188 1.000 rs10060400 chr5:77874205 G/A cg06873401 chr5:77792105 LHFPL2 -0.22 -4.46 -0.37 1.79e-5 Pulse pressure; TGCT cis rs7178572 1.000 rs34591043 chr15:77713586 A/G cg15453836 chr15:77711506 NA -0.4 -4.56 -0.38 1.22e-5 Type 2 diabetes; TGCT cis rs12188164 0.965 rs1056465 chr5:442438 T/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs3733585 0.631 rs3822236 chr4:10119961 T/G cg11266682 chr4:10021025 SLC2A9 -0.55 -6.35 -0.5 3.78e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7772486 0.764 rs7745696 chr6:146162829 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.77 0.39 5.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs739401 0.572 rs12276060 chr11:3015572 A/T cg05729581 chr11:3078854 CARS -0.6 -5.43 -0.44 2.79e-7 Longevity; TGCT cis rs4927850 0.918 rs4361313 chr3:195752260 A/G cg12923728 chr3:195709715 SDHAP1 -0.36 -7.57 -0.56 7.39e-12 Pancreatic cancer; TGCT cis rs9362426 1.000 rs9294377 chr6:88084839 G/A cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.19 0.42 8.5e-7 Depressive episodes in bipolar disorder; TGCT cis rs62283056 1.000 rs62283056 chr4:6276630 G/C cg25554036 chr4:6271136 WFS1 -0.44 -4.78 -0.39 4.93e-6 Cisplatin-induced ototoxicity; TGCT cis rs4665809 0.941 rs1434079 chr2:26284670 C/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs765787 0.530 rs2413775 chr15:45544288 T/A cg24006582 chr15:45444508 DUOX1 -0.27 -5.85 -0.46 4.18e-8 Uric acid levels; TGCT cis rs2840044 0.534 rs321596 chr17:33885736 C/T cg05299278 chr17:33885742 SLFN14 -0.23 -5.12 -0.42 1.13e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs4788815 0.532 rs59709630 chr16:71978608 G/T cg06353428 chr16:71660113 MARVELD3 0.78 7.05 0.53 1.12e-10 Metabolite levels; TGCT trans rs6089829 0.925 rs13041507 chr20:61666180 T/C cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs28386778 0.897 rs2236737 chr17:61938100 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs933688 0.938 rs1477348 chr5:90707823 G/A cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.02 8.35 0.6 1.17e-13 Smoking behavior; TGCT cis rs7635838 0.892 rs3942925 chr3:11442921 T/C cg00170343 chr3:11313890 ATG7 0.64 6.15 0.48 9.88e-9 HDL cholesterol; TGCT cis rs9660180 0.967 rs6687065 chr1:1778469 A/G cg03396347 chr1:1875803 NA -0.36 -6.48 -0.5 1.97e-9 Body mass index; TGCT cis rs4819052 0.765 rs2838868 chr21:46714641 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.89 -7.89 -0.58 1.39e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs35306767 0.761 rs12770173 chr10:1027108 A/C cg20503657 chr10:835505 NA 0.59 6.67 0.51 7.75e-10 Eosinophil percentage of granulocytes; TGCT cis rs9325144 0.505 rs1906262 chr12:38653605 A/G cg13010199 chr12:38710504 ALG10B 0.58 5.2 0.42 8.08e-7 Morning vs. evening chronotype; TGCT cis rs7811142 0.830 rs11771936 chr7:99943283 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.92 7.32 0.55 2.79e-11 Platelet count; TGCT cis rs9952991 1.000 rs9952991 chr18:12780464 G/A cg23598886 chr18:12777645 NA 0.6 5.58 0.45 1.41e-7 Inflammatory skin disease; TGCT cis rs2486288 0.656 rs2413771 chr15:45553140 A/G cg14582100 chr15:45693742 SPATA5L1 -0.48 -5.77 -0.46 5.91e-8 Glomerular filtration rate; TGCT cis rs3785574 0.962 rs2584621 chr17:61912436 G/A cg01411255 chr17:61851458 DDX42;CCDC47 1.11 13.91 0.78 4.47e-27 Height; TGCT cis rs3806843 0.576 rs246032 chr5:140332547 C/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs7402982 0.625 rs7179841 chr15:99204652 C/T cg03437748 chr15:99193247 IGF1R 0.46 4.62 0.38 9.38e-6 Birth weight; TGCT cis rs8063761 1.000 rs8063761 chr16:90027626 A/T cg08547343 chr16:90038815 CENPBD1;AFG3L1 0.58 5.34 0.43 4.19e-7 Squamous cell carcinoma; TGCT cis rs28386778 0.799 rs2584612 chr17:61932204 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.46 0.56 1.3e-11 Prudent dietary pattern; TGCT cis rs1005224 0.895 rs6574252 chr14:76141834 C/T cg04684003 chr14:76127793 TTLL5;C14orf1 -0.61 -5.59 -0.45 1.36e-7 Large artery stroke; TGCT cis rs10504229 0.906 rs7003285 chr8:58173108 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg04389838 chr3:44770851 ZNF501 -0.43 -5.67 -0.45 9.4e-8 Depressive symptoms; TGCT cis rs10883723 0.962 rs1056739 chr10:104236542 T/C cg05855489 chr10:104503620 C10orf26 -0.55 -4.68 -0.39 7.42e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs5769707 0.967 rs2187891 chr22:49994094 C/T cg20744362 chr22:50050164 C22orf34 0.27 4.58 0.38 1.09e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7552404 1.000 rs12091720 chr1:76186949 G/A cg03433033 chr1:76189801 ACADM 0.82 9.68 0.66 7.51e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6684514 1.000 rs10908499 chr1:156279176 G/C cg20302342 chr1:156215951 PAQR6 0.36 4.77 0.39 5.1e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6921919 0.559 rs13210866 chr6:28383842 G/A cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2980439 0.517 rs17594065 chr8:8105405 T/C cg06636001 chr8:8085503 FLJ10661 -0.61 -5.33 -0.43 4.51e-7 Neuroticism; TGCT cis rs6964587 0.967 rs6980247 chr7:91594228 T/A cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs77669868 0.929 rs3782002 chr11:114070563 A/T cg01914181 chr11:114070210 ZBTB16 0.33 5.73 0.46 7.25e-8 Monocyte percentage of white cells; TGCT cis rs1862618 0.671 rs2591958 chr5:56239369 C/G cg20203395 chr5:56204925 C5orf35 0.53 4.92 0.4 2.67e-6 Initial pursuit acceleration; TGCT trans rs7618501 0.521 rs2352984 chr3:49948728 T/C cg21659725 chr3:3221576 CRBN 0.71 8.01 0.58 6.98e-13 Intelligence (multi-trait analysis); TGCT cis rs854765 0.964 rs12943202 chr17:17994332 T/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.63 -5.96 -0.47 2.46e-8 Total body bone mineral density; TGCT cis rs1784581 0.802 rs2156747 chr6:162430000 C/G cg17173639 chr6:162384350 PARK2 -0.41 -7.34 -0.55 2.52e-11 Itch intensity from mosquito bite; TGCT cis rs9467711 1.000 rs9467708 chr6:26327956 T/C cg16898833 chr6:26189333 HIST1H4D 1.04 5.51 0.44 1.97e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs514406 0.548 rs6670871 chr1:53212082 A/C cg01802117 chr1:53393560 SCP2 0.44 5.14 0.42 1.05e-6 Monocyte count; TGCT cis rs79149102 0.579 rs74025863 chr15:75284161 T/C cg09165964 chr15:75287851 SCAMP5 -1.07 -5.89 -0.47 3.42e-8 Lung cancer; TGCT cis rs4654899 0.644 rs6669077 chr1:21290520 A/C cg01072550 chr1:21505969 NA -0.56 -9.13 -0.63 1.61e-15 Superior frontal gyrus grey matter volume; TGCT cis rs9611565 0.512 rs139566 chr22:42199277 A/G cg06481639 chr22:41940642 POLR3H -0.69 -5.92 -0.47 2.91e-8 Vitiligo; TGCT cis rs2762353 0.574 rs9461204 chr6:25718466 A/G cg07061783 chr6:25882402 NA 0.72 7.44 0.56 1.44e-11 Blood metabolite levels; TGCT cis rs7586879 0.681 rs28836469 chr2:25117215 A/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs2730260 0.537 rs55662704 chr7:158864184 T/C cg27122614 chr7:157913741 PTPRN2 0.43 4.46 0.37 1.81e-5 Myopia (pathological); TGCT cis rs9393692 0.875 rs2142703 chr6:26289605 A/G cg05868516 chr6:26286170 HIST1H4H 0.63 5.91 0.47 3.02e-8 Educational attainment; TGCT cis rs2120019 1.000 rs12898259 chr15:75369780 G/A cg09165964 chr15:75287851 SCAMP5 -1.07 -8.58 -0.61 3.34e-14 Blood trace element (Zn levels); TGCT cis rs2439831 0.850 rs7174208 chr15:44052682 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.87 5.91 0.47 3.05e-8 Lung cancer in ever smokers; TGCT cis rs7020830 0.931 rs1388978 chr9:37144062 G/T cg14294708 chr9:37120828 ZCCHC7 1.18 15.98 0.82 6.73e-32 Schizophrenia; TGCT cis rs13326165 0.760 rs28481563 chr3:52417638 T/C cg07884673 chr3:53033167 SFMBT1 0.4 4.86 0.4 3.45e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs2762353 0.595 rs9467591 chr6:25742699 C/T cg15691649 chr6:25882328 NA -0.45 -5.51 -0.44 1.97e-7 Blood metabolite levels; TGCT cis rs6952808 0.626 rs57633152 chr7:2042547 C/G cg22963979 chr7:1858916 MAD1L1 -0.39 -5.95 -0.47 2.5e-8 Bipolar disorder and schizophrenia; TGCT cis rs8056742 0.642 rs67300532 chr16:85029995 C/A cg00229868 chr16:85520891 NA 0.37 4.64 0.38 8.75e-6 Amyotrophic lateral sclerosis; TGCT cis rs11792861 0.926 rs7870597 chr9:111871864 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.48 4.48 0.37 1.66e-5 Menarche (age at onset); TGCT cis rs4253772 0.550 rs739164 chr22:46684558 C/T cg03482458 chr22:46692211 CN5H6.4;GTSE1 -0.7 -5.27 -0.43 5.83e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9372498 0.536 rs9489457 chr6:118920285 C/T cg21191810 chr6:118973309 C6orf204 -0.39 -5.13 -0.42 1.07e-6 Diastolic blood pressure; TGCT cis rs17376456 0.877 rs9314092 chr5:93326362 A/G cg25358565 chr5:93447407 FAM172A 0.98 8.59 0.61 3.14e-14 Diabetic retinopathy; TGCT cis rs2594989 0.831 rs13324245 chr3:11570769 T/G cg26283222 chr3:11613257 VGLL4 0.21 4.49 0.37 1.62e-5 Circulating chemerin levels; TGCT cis rs4455778 0.580 rs4270911 chr7:49112131 T/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs6089584 0.888 rs2146853 chr20:60617908 A/T cg06108461 chr20:60628389 TAF4 -0.69 -10.77 -0.7 1.71e-19 Body mass index; TGCT cis rs10504229 0.906 rs7842482 chr8:58167720 A/T cg21724239 chr8:58056113 NA 0.39 5.28 0.43 5.67e-7 Developmental language disorder (linguistic errors); TGCT cis rs67311347 1.000 rs12488805 chr3:40422869 C/T cg17264618 chr3:40429014 ENTPD3 0.34 4.81 0.4 4.34e-6 Renal cell carcinoma; TGCT cis rs896854 0.654 rs10104909 chr8:95977973 C/T cg23172400 chr8:95962367 TP53INP1 -0.36 -6.14 -0.48 1.05e-8 Type 2 diabetes; TGCT cis rs7959452 0.590 rs11177644 chr12:69785748 A/G cg14784868 chr12:69753453 YEATS4 0.83 8.96 0.63 4.14e-15 Blood protein levels; TGCT cis rs2066819 1.000 rs59295315 chr12:56708576 G/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs17152411 1.000 rs7914110 chr10:126599886 C/G cg07906193 chr10:126599966 NA 0.41 5.03 0.41 1.71e-6 Height; TGCT cis rs9921192 0.967 rs233956 chr16:4332858 C/T cg00021532 chr16:4324280 TFAP4 0.82 9.12 0.63 1.66e-15 Prostate-specific antigen levels; TGCT cis rs933688 1.000 rs60513756 chr5:90727692 A/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.27 0.6 1.74e-13 Smoking behavior; TGCT cis rs9368481 0.761 rs12661756 chr6:27003483 A/G cg18278486 chr6:26987575 LOC100270746;C6orf41 0.38 4.67 0.39 7.61e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs10927875 0.800 rs1627145 chr1:16328116 C/T cg22431228 chr1:16359049 CLCNKA -0.25 -4.8 -0.4 4.39e-6 Dilated cardiomyopathy; TGCT cis rs62103177 0.584 rs9956207 chr18:77968392 A/G cg07235805 chr18:78004237 PARD6G -0.51 -5.1 -0.42 1.25e-6 Opioid sensitivity; TGCT cis rs8078723 0.674 rs9303284 chr17:38205793 C/T cg17467752 chr17:38218738 THRA -0.73 -7.17 -0.54 6.03e-11 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs3796352 0.667 rs3755805 chr3:52866299 G/A cg07884673 chr3:53033167 SFMBT1 0.62 5.35 0.43 4.16e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3008870 0.583 rs2815369 chr1:67500894 T/C cg11518657 chr1:67396239 MIER1 0.61 4.81 0.4 4.26e-6 Lymphocyte percentage of white cells; TGCT cis rs13108904 0.870 rs4493483 chr4:1279916 G/A cg00684032 chr4:1343700 KIAA1530 0.22 4.9 0.4 2.93e-6 Obesity-related traits; TGCT cis rs10197940 0.624 rs6724796 chr2:152412813 C/T cg06191203 chr2:152266755 RIF1 -0.75 -7.03 -0.53 1.21e-10 Lung cancer; TGCT cis rs4906332 0.966 rs4906331 chr14:103971374 C/T cg26031613 chr14:104095156 KLC1 -0.54 -4.66 -0.39 8.15e-6 Coronary artery disease; TGCT cis rs9467711 0.606 rs2073530 chr6:26375243 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4595586 0.546 rs2056159 chr12:39270417 C/G cg13010199 chr12:38710504 ALG10B 0.62 4.86 0.4 3.45e-6 Morning vs. evening chronotype; TGCT trans rs1864729 0.748 rs2635138 chr8:98301418 A/G cg08679828 chr8:102218111 ZNF706 1.04 6.94 0.53 1.9e-10 Estradiol plasma levels (breast cancer); TGCT cis rs637571 0.510 rs4930320 chr11:65576788 C/G cg04055107 chr11:65626734 MUS81;CFL1 -0.67 -6.01 -0.48 1.9e-8 Eosinophil percentage of white cells; TGCT cis rs1799949 0.965 rs8176193 chr17:41231516 C/T cg23758822 chr17:41437982 NA 0.72 6.84 0.52 3.18e-10 Menopause (age at onset); TGCT cis rs2742234 0.910 rs2503866 chr10:43646261 T/A cg02780029 chr10:43622663 RET -0.26 -5.05 -0.41 1.57e-6 Hirschsprung disease; TGCT cis rs1580019 0.587 rs7806113 chr7:32553084 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.11 14.04 0.78 2.14e-27 Cognitive ability; TGCT cis rs4319547 0.774 rs7959238 chr12:123131498 A/T cg05707623 chr12:122985044 ZCCHC8 -0.65 -5.52 -0.44 1.89e-7 Body mass index; TGCT cis rs7681440 0.904 rs28415623 chr4:90767110 C/T cg20003494 chr4:90757398 SNCA -0.62 -5.93 -0.47 2.74e-8 Dementia with Lewy bodies; TGCT cis rs1862618 0.853 rs832565 chr5:56150803 T/G cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs1862618 0.754 rs252899 chr5:56188569 G/C cg12311346 chr5:56204834 C5orf35 -0.67 -6.78 -0.52 4.34e-10 Initial pursuit acceleration; TGCT cis rs6088580 0.634 rs6142153 chr20:32968747 C/G cg06115741 chr20:33292138 TP53INP2 -0.53 -4.67 -0.39 7.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs7772486 0.790 rs2265474 chr6:146182092 G/A cg13319975 chr6:146136371 FBXO30 -0.54 -4.89 -0.4 3.07e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9948 0.786 rs62156230 chr2:97424915 A/G cg01990225 chr2:97406019 LMAN2L -0.8 -5.02 -0.41 1.74e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs1034435 0.723 rs713946 chr22:48891376 T/C cg05992904 chr22:48892994 FAM19A5 -0.34 -4.64 -0.38 8.54e-6 Late-onset Alzheimer's disease; TGCT cis rs13326165 0.715 rs34908451 chr3:52385115 C/T cg07884673 chr3:53033167 SFMBT1 0.39 4.69 0.39 7e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7192750 0.586 rs13329779 chr16:71943940 T/C cg06353428 chr16:71660113 MARVELD3 0.82 7.26 0.55 3.82e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs2677744 0.688 rs6496737 chr15:91455618 C/T cg23684204 chr15:91497937 RCCD1 0.33 4.81 0.4 4.32e-6 Attention deficit hyperactivity disorder; TGCT cis rs1843834 0.931 rs10170573 chr2:225552916 A/G cg22455342 chr2:225449267 CUL3 0.75 7.37 0.55 2.15e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs9926296 0.656 rs2376881 chr16:89827011 C/G cg03388025 chr16:89894329 SPIRE2 0.31 4.57 0.38 1.18e-5 Vitiligo; TGCT cis rs9926296 0.557 rs11076618 chr16:89807705 T/C cg03388025 chr16:89894329 SPIRE2 0.33 4.78 0.39 4.85e-6 Vitiligo; TGCT cis rs4819052 0.819 rs34818688 chr21:46672416 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8013055 0.699 rs66798104 chr14:105987782 C/G cg19700328 chr14:106028568 NA -0.53 -5.79 -0.46 5.38e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs10875746 0.951 rs10875756 chr12:48562304 C/T cg20731937 chr12:48336164 NA 0.62 4.94 0.41 2.46e-6 Longevity (90 years and older); TGCT cis rs10504229 0.817 rs60646469 chr8:58195348 T/C cg24829409 chr8:58192753 C8orf71 -0.53 -4.57 -0.38 1.18e-5 Developmental language disorder (linguistic errors); TGCT cis rs7809950 1.000 rs2520269 chr7:107191327 T/C cg23024343 chr7:107201750 COG5 -0.35 -5.47 -0.44 2.36e-7 Coronary artery disease; TGCT cis rs7224685 0.569 rs12452393 chr17:3985427 G/A cg09580393 chr17:4869866 SPAG7 -0.39 -4.5 -0.37 1.56e-5 Type 2 diabetes; TGCT cis rs1887596 0.607 rs9553870 chr13:27170716 G/A cg01312412 chr13:27282625 NA 0.32 5.74 0.46 6.84e-8 Facial morphology (factor 3, length of philtrum); TGCT cis rs1552244 1.000 rs9824585 chr3:10114802 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs11190604 1.000 rs11190602 chr10:102297256 T/C cg16342193 chr10:102329863 NA -0.41 -5.11 -0.42 1.18e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs13191362 1.000 rs34138336 chr6:163144929 A/G cg06582575 chr6:163149167 PACRG;PARK2 1.0 7.73 0.57 3.24e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg02953382 chr22:24373134 LOC391322 -0.79 -8.35 -0.6 1.15e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs67311347 1.000 rs7628796 chr3:40507332 G/A cg13683864 chr3:40499215 RPL14 1.17 13.19 0.76 2.34e-25 Renal cell carcinoma; TGCT cis rs775227 0.574 rs13067967 chr3:113265215 C/G cg18753928 chr3:113234510 CCDC52 -0.66 -4.49 -0.37 1.64e-5 Dental caries; TGCT cis rs9443645 0.901 rs9359354 chr6:79590385 A/G cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs12681287 0.640 rs10098356 chr8:87442667 A/G cg27223183 chr8:87520930 FAM82B 0.89 6.43 0.5 2.54e-9 Caudate activity during reward; TGCT cis rs2650000 0.798 rs2701175 chr12:121391671 C/A cg02403541 chr12:121454288 C12orf43 -0.62 -5.3 -0.43 5.11e-7 Metabolic traits;LDL cholesterol; TGCT cis rs6748734 0.894 rs4675869 chr2:241827696 A/G cg04034577 chr2:241836375 C2orf54 -0.4 -6.32 -0.49 4.22e-9 Urinary metabolites; TGCT cis rs501916 0.796 rs55961203 chr15:48050518 G/T cg16110827 chr15:48056943 SEMA6D -0.17 -4.73 -0.39 5.93e-6 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs12762955 0.519 rs10795306 chr10:1019138 A/T cg18964960 chr10:1102726 WDR37 -0.69 -6.19 -0.49 8.21e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs4819052 0.765 rs2838854 chr21:46680364 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs394563 0.591 rs6570963 chr6:149691355 T/G cg11245181 chr6:149772854 ZC3H12D 0.28 4.48 0.37 1.7e-5 Dupuytren's disease; TGCT cis rs10089 0.951 rs736969 chr5:127466347 G/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.43 0.56 1.53e-11 Ileal carcinoids; TGCT cis rs6570726 0.557 rs403956 chr6:145829956 T/C cg05347473 chr6:146136440 FBXO30 0.62 5.72 0.46 7.48e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs17767294 0.708 rs72845060 chr6:27648935 G/A cg08851530 chr6:28072375 NA 1.55 6.56 0.51 1.32e-9 Parkinson's disease; TGCT cis rs7666738 0.830 rs6831588 chr4:98977356 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9911578 0.803 rs8069033 chr17:57131581 T/A cg12560992 chr17:57184187 TRIM37 -0.78 -9.67 -0.66 7.8e-17 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs11021319 chr11:95523123 C/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs208520 0.690 rs851468 chr6:66825875 G/A cg07460842 chr6:66804631 NA -0.95 -9.88 -0.66 2.43e-17 Exhaled nitric oxide output; TGCT cis rs8177179 0.967 rs10935085 chr3:133459735 C/T cg24879335 chr3:133465180 TF 0.36 4.86 0.4 3.46e-6 Iron status biomarkers (transferrin levels); TGCT cis rs57590327 0.503 rs6802480 chr3:81906671 G/A cg07356753 chr3:81810745 GBE1 -0.7 -6.42 -0.5 2.68e-9 Extraversion; TGCT cis rs7959452 0.590 rs7968629 chr12:69782857 G/A cg11871910 chr12:69753446 YEATS4 0.82 8.95 0.63 4.38e-15 Blood protein levels; TGCT cis rs524281 0.861 rs10896080 chr11:65876796 G/A cg00563793 chr11:65837595 PACS1 0.54 4.55 0.38 1.24e-5 Electroencephalogram traits; TGCT trans rs916888 0.531 rs183211 chr17:44788310 G/A cg01341218 chr17:43662625 NA 0.83 7.32 0.55 2.77e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8008002 0.930 rs8007827 chr14:75865458 G/T cg20011974 chr14:75469661 EIF2B2 -0.5 -4.48 -0.37 1.65e-5 Response to paliperidone in schizophrenia (positive Marder score); TGCT cis rs6684514 1.000 rs12041164 chr1:156279811 G/A cg16558208 chr1:156270281 VHLL 0.48 9.61 0.65 1.13e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs9318086 0.578 rs2077709 chr13:24476073 A/G cg25267304 chr13:24462978 PCOTH;MIPEP -0.83 -9.34 -0.64 4.98e-16 Myopia (pathological); TGCT cis rs8103278 0.507 rs522769 chr19:46284520 G/A cg14061069 chr19:46274453 DMPK 0.61 10.51 0.69 7.14e-19 Coronary artery disease; TGCT cis rs5771242 0.518 rs6010216 chr22:50679471 C/T cg16473166 chr22:50639996 SELO 0.63 5.29 0.43 5.24e-7 Lung function (forced expiratory flow during mid-portion (25% and 75%) of forced vital capacity); TGCT cis rs2228479 0.867 rs11642451 chr16:89958127 T/C cg06558623 chr16:89946397 TCF25 0.56 6.83 0.52 3.38e-10 Skin colour saturation; TGCT cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg06634786 chr22:41940651 POLR3H 0.89 8.55 0.61 3.83e-14 Vitiligo; TGCT cis rs2749592 0.513 rs1208708 chr10:38085576 A/G cg25427524 chr10:38739819 LOC399744 -0.37 -7.42 -0.55 1.6e-11 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs9814567 1.000 rs13059720 chr3:134242021 T/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1475911 0.708 rs11701371 chr21:43523972 C/G cg14562523 chr21:43528734 C21orf128;UMODL1 -0.26 -5.23 -0.43 6.91e-7 IgG glycosylation; TGCT cis rs1538970 0.924 rs3790582 chr1:45887288 T/C cg05343316 chr1:45956843 TESK2 0.77 6.2 0.49 7.66e-9 Platelet count; TGCT cis rs68092024 0.704 rs792832 chr3:99474862 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.51 6.19 0.49 8.23e-9 Cleft lip with or without cleft palate; TGCT trans rs3780486 0.846 rs10971420 chr9:33125000 T/C cg20290983 chr6:43655470 MRPS18A 1.18 14.81 0.8 3.33e-29 IgG glycosylation; TGCT trans rs7618501 0.699 rs6446187 chr3:49907111 C/A cg21665057 chr3:196295764 WDR53;FBXO45 0.9 9.84 0.66 3.04e-17 Intelligence (multi-trait analysis); TGCT cis rs9436747 0.641 rs4655519 chr1:66039919 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.54 5.11 0.42 1.17e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs80282103 0.867 rs17155821 chr10:1071701 A/G cg18964960 chr10:1102726 WDR37 1.08 4.63 0.38 9.23e-6 Glomerular filtration rate (creatinine); TGCT cis rs1799949 1.000 rs33920795 chr17:41329010 A/G cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.83e-10 Menopause (age at onset); TGCT cis rs11122272 0.735 rs2486727 chr1:231539245 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.28 -0.49 5.32e-9 Hemoglobin concentration; TGCT cis rs7811142 0.775 rs6946768 chr7:99954393 G/A cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT trans rs1814175 0.817 rs1319547 chr11:49916705 C/T cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT cis rs7681440 0.904 rs7671549 chr4:90771147 T/A cg26578617 chr4:90757533 SNCA -0.46 -4.73 -0.39 6.01e-6 Dementia with Lewy bodies; TGCT cis rs2816062 0.813 rs2816057 chr1:18902257 G/C cg18795169 chr1:18902165 NA -0.6 -13.83 -0.78 6.99e-27 Urate levels in lean individuals; TGCT cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg18230493 chr5:56204884 C5orf35 -0.67 -5.76 -0.46 6.2e-8 Initial pursuit acceleration; TGCT cis rs9653442 0.522 rs4851274 chr2:100870862 T/C cg07810366 chr2:100720526 AFF3 -0.38 -5.71 -0.46 7.81e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs12118280 1.000 rs12118280 chr1:108738780 T/C cg11967332 chr1:108735228 SLC25A24 0.39 5.41 0.44 3.15e-7 Myeloid white cell count; TGCT cis rs4862750 0.914 rs1991256 chr4:187875330 A/G cg03452623 chr4:187889614 NA -0.38 -5.84 -0.46 4.25e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs6540559 0.611 rs17015226 chr1:209970096 C/G cg04352962 chr1:209979756 IRF6 0.68 4.79 0.4 4.64e-6 Cleft lip with or without cleft palate; TGCT cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.84 0.46 4.39e-8 Height; TGCT cis rs13326165 0.760 rs11706001 chr3:52372128 T/A cg27565382 chr3:53032988 SFMBT1 0.37 4.91 0.4 2.84e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs904251 0.525 rs12200378 chr6:37425304 A/G cg08126542 chr6:37504118 NA -0.41 -5.73 -0.46 7.35e-8 Cognitive performance; TGCT cis rs7666738 0.927 rs11736876 chr4:98987206 A/G cg05340658 chr4:99064831 C4orf37 0.49 4.88 0.4 3.14e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6688613 0.694 rs11576455 chr1:166811970 G/A cg07049167 chr1:166818506 POGK 0.24 4.87 0.4 3.34e-6 Refractive astigmatism; TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg25151919 chr3:44754333 ZNF502 -0.42 -4.91 -0.4 2.81e-6 Depressive symptoms; TGCT cis rs6840360 1.000 rs751014 chr4:152601902 G/A cg17479576 chr4:152424074 FAM160A1 -0.52 -5.66 -0.45 9.86e-8 Intelligence (multi-trait analysis); TGCT cis rs9914988 0.943 rs4794838 chr17:27131095 T/C cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs769267 0.930 rs3794990 chr19:19610030 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs909341 0.909 rs6122158 chr20:62363096 G/A cg14758556 chr20:62440591 NA 0.3 4.53 0.38 1.38e-5 Atopic dermatitis; TGCT cis rs924607 1.000 rs4045344 chr5:595870 G/T cg04476341 chr5:669733 TPPP -0.25 -4.49 -0.37 1.64e-5 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs6912958 1.000 rs9294380 chr6:88152667 G/A cg12350822 chr6:88032061 C6orf162;GJB7 -0.36 -4.55 -0.38 1.28e-5 Monocyte percentage of white cells; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg15242686 chr22:24348715 GSTTP1 0.44 5.87 0.47 3.81e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3812831 0.654 rs367312 chr13:114930195 G/A cg08824895 chr13:115047677 UPF3A 0.48 5.14 0.42 1.02e-6 Schizophrenia; TGCT trans rs916888 0.697 rs199516 chr17:44856485 C/T cg22968622 chr17:43663579 NA -1.24 -11.32 -0.71 7.53e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs116095464 0.558 rs6555052 chr5:224268 G/A cg12570787 chr5:219185 SDHA;CCDC127 0.65 4.46 0.37 1.83e-5 Breast cancer; TGCT cis rs3733585 0.664 rs28602527 chr4:9958327 G/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs4972806 0.814 rs2113560 chr2:177030986 T/C cg13092806 chr2:177043255 NA 0.56 4.81 0.4 4.33e-6 IgG glycosylation; TGCT cis rs6964587 1.000 rs58965837 chr7:91585258 T/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs6790105 1 rs6790105 chr3:49393409 C/T cg07636037 chr3:49044803 WDR6 0.66 5.33 0.43 4.45e-7 Childhood ear infection; TGCT cis rs3796352 1.000 rs35507120 chr3:53053924 C/T cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs79349575 0.783 rs2088139 chr17:47000110 C/T cg26022315 chr17:47021804 SNF8 0.48 4.8 0.4 4.52e-6 Type 2 diabetes; TGCT cis rs7017914 0.870 rs3098877 chr8:71936446 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -4.97 -0.41 2.16e-6 Bone mineral density; TGCT cis rs59698941 0.550 rs11748737 chr5:132201070 C/T cg21474247 chr5:131268130 NA 0.31 4.77 0.39 5.01e-6 Apolipoprotein A-IV levels; TGCT cis rs875971 0.830 rs6967708 chr7:65657313 A/T cg11764359 chr7:65958608 NA -0.56 -5.06 -0.41 1.45e-6 Aortic root size; TGCT cis rs3617 0.539 rs4687687 chr3:52948332 A/G cg11645453 chr3:52864694 ITIH4 -0.27 -5.32 -0.43 4.74e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs28595532 0.920 rs17259173 chr4:119777232 T/C cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs769267 0.965 rs2315024 chr19:19423817 T/A cg20644253 chr19:19431407 KIAA0892;SF4 0.68 6.05 0.48 1.57e-8 Tonsillectomy; TGCT cis rs2832191 0.967 rs1999321 chr21:30530233 A/C cg24692254 chr21:30365293 RNF160 0.75 7.4 0.55 1.78e-11 Dental caries; TGCT cis rs3858526 0.883 rs11039686 chr11:5948725 T/C cg05234568 chr11:5960015 NA -0.47 -4.56 -0.38 1.21e-5 DNA methylation (variation); TGCT cis rs3617 0.522 rs6773650 chr3:52897095 A/T cg10802521 chr3:52805072 NEK4 -0.56 -6.36 -0.5 3.6e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2629540 0.889 rs4962696 chr10:126445630 A/G cg08799069 chr10:126477246 METTL10 -0.31 -4.7 -0.39 6.75e-6 Cocaine dependence; TGCT cis rs13191362 0.938 rs13192618 chr6:163132822 T/C cg21926612 chr6:163149169 PACRG;PARK2 1.07 8.83 0.62 8.46e-15 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7267979 1.000 rs2258201 chr20:25272490 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11711311 0.712 rs3773684 chr3:113334488 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 0.62 5.11 0.42 1.16e-6 IgG glycosylation; TGCT cis rs651907 0.557 rs3864012 chr3:101397623 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.55 5.24 0.43 6.66e-7 Colorectal cancer; TGCT cis rs7940866 0.803 rs10894307 chr11:130876350 G/A cg12179176 chr11:130786555 SNX19 0.58 5.5 0.44 2.04e-7 Schizophrenia; TGCT cis rs35306767 0.623 rs36051896 chr10:1155747 T/C cg20503657 chr10:835505 NA 0.54 5.8 0.46 5.25e-8 Eosinophil percentage of granulocytes; TGCT cis rs41271951 0.512 rs6664387 chr1:151021509 A/G cg00666978 chr1:150947442 LASS2 0.89 4.64 0.38 8.54e-6 Blood protein levels; TGCT cis rs6752107 0.936 rs6431660 chr2:234167234 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.79 0.39 4.74e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs597539 0.690 rs608810 chr11:68624118 G/C cg21862992 chr11:68658383 NA 0.48 6.35 0.5 3.63e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs425277 0.628 rs3107147 chr1:2048729 G/A cg03732007 chr1:2071316 PRKCZ -0.26 -5.9 -0.47 3.17e-8 Height; TGCT cis rs2637266 0.967 rs7900230 chr10:78366879 A/G cg18941641 chr10:78392320 NA 0.39 4.88 0.4 3.24e-6 Pulmonary function; TGCT cis rs6951245 1.000 rs74887741 chr7:1110658 G/T cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs1799949 1.000 rs4793189 chr17:41190715 G/A cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs921968 0.542 rs588182 chr2:219412335 C/A cg02176678 chr2:219576539 TTLL4 0.48 6.86 0.52 2.94e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs9660992 0.573 rs4400674 chr1:205218425 A/C cg00857998 chr1:205179979 DSTYK -0.5 -4.67 -0.39 7.78e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs10256972 0.694 rs7784701 chr7:1003041 A/G cg07930192 chr7:1003750 NA 0.3 4.72 0.39 6.33e-6 Longevity;Endometriosis; TGCT cis rs9467773 1.000 rs767471 chr6:26557854 C/T cg05738196 chr6:26577821 NA 0.91 13.19 0.76 2.28e-25 Intelligence (multi-trait analysis); TGCT cis rs734999 0.545 rs4648565 chr1:2570023 A/G cg18854424 chr1:2615690 NA -0.45 -5.15 -0.42 1e-6 Ulcerative colitis; TGCT cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg02458000 chr6:26745757 NA 0.59 5.92 0.47 2.93e-8 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.580 rs1932282 chr6:8477330 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT trans rs2727020 0.636 rs10839275 chr11:49438962 T/A cg03929089 chr4:120376271 NA -0.74 -8.55 -0.61 3.78e-14 Coronary artery disease; TGCT cis rs7617773 0.746 rs7619865 chr3:48370580 G/A cg11946769 chr3:48343235 NME6 0.73 6.76 0.52 4.71e-10 Coronary artery disease; TGCT cis rs2439831 0.717 rs2447198 chr15:43895118 T/C cg02155558 chr15:43621948 ADAL;LCMT2 0.97 6.69 0.52 6.74e-10 Lung cancer in ever smokers; TGCT cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs7829975 0.811 rs7011229 chr8:8543324 T/C cg08975724 chr8:8085496 FLJ10661 -0.53 -4.58 -0.38 1.11e-5 Mood instability; TGCT cis rs8177253 1.000 rs6439439 chr3:133481498 G/T cg08048268 chr3:133502702 NA -0.66 -9.83 -0.66 3.36e-17 Iron status biomarkers; TGCT cis rs4689388 0.926 rs10012946 chr4:6293350 C/T cg25554036 chr4:6271136 WFS1 -0.55 -6.98 -0.53 1.54e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9549367 0.789 rs8001506 chr13:113867153 A/C cg00898013 chr13:113819073 PROZ -0.41 -5.32 -0.43 4.59e-7 Platelet distribution width; TGCT cis rs9796 0.654 rs2947489 chr15:41459576 T/A cg18705301 chr15:41695430 NDUFAF1 0.54 7.22 0.54 4.66e-11 Menopause (age at onset); TGCT cis rs12541335 0.639 rs13257108 chr8:22165043 T/C cg26039829 chr8:22132926 PIWIL2 0.27 5.18 0.42 8.83e-7 Hypertriglyceridemia; TGCT cis rs4242434 0.819 rs6999893 chr8:22465427 T/C cg03733263 chr8:22462867 KIAA1967 1.08 17.46 0.84 3.22e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs713587 0.719 rs4665736 chr2:25187599 C/T cg01884057 chr2:25150051 NA -0.38 -7.8 -0.57 2.16e-12 Body mass index in non-asthmatics; TGCT cis rs2836974 0.644 rs2410123 chr21:40700093 C/T cg11644478 chr21:40555479 PSMG1 -0.6 -4.98 -0.41 2.05e-6 Cognitive function; TGCT cis rs8177253 1.000 rs8177272 chr3:133482870 C/T cg11941060 chr3:133502564 NA -0.29 -6.16 -0.48 9.17e-9 Iron status biomarkers; TGCT cis rs12780845 0.540 rs10490959 chr10:17230836 A/T cg01003015 chr10:17271136 VIM -0.49 -4.46 -0.37 1.82e-5 Homocysteine levels; TGCT cis rs12579753 1.000 rs11115047 chr12:82232773 C/G cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs4073582 0.595 rs801731 chr11:65938446 G/C cg16950941 chr11:66035639 RAB1B 0.55 5.42 0.44 2.94e-7 Gout; TGCT cis rs9326248 1.000 rs7946257 chr11:117053165 A/G cg16524733 chr11:117070046 TAGLN 0.32 4.56 0.38 1.23e-5 Blood protein levels; TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg08736216 chr1:53307985 ZYG11A -0.28 -5.38 -0.44 3.57e-7 Monocyte count; TGCT cis rs992157 0.835 rs7559416 chr2:219150211 A/G cg00012203 chr2:219082015 ARPC2 -0.77 -7.64 -0.57 5.1e-12 Colorectal cancer; TGCT cis rs7208859 0.623 rs78071511 chr17:29128154 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11122272 0.705 rs1416914 chr1:231533196 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.74 -7.35 -0.55 2.3e-11 Hemoglobin concentration; TGCT cis rs4786125 0.626 rs6500859 chr16:6914358 A/T cg03623568 chr16:6915990 A2BP1 -0.39 -5.83 -0.46 4.41e-8 Heart rate variability traits (SDNN); TGCT cis rs2486012 0.737 rs6670344 chr1:44269208 A/G cg12908607 chr1:44402522 ARTN -0.71 -5.54 -0.45 1.75e-7 Intelligence (multi-trait analysis); TGCT cis rs16957091 0.647 rs28613047 chr15:43176165 G/A cg17935677 chr15:44119062 WDR76 0.52 4.71 0.39 6.44e-6 MGMT methylation in smokers; TGCT cis rs2836974 0.568 rs2183573 chr21:40574305 A/G cg11890956 chr21:40555474 PSMG1 -0.79 -7.72 -0.57 3.29e-12 Cognitive function; TGCT cis rs35306767 0.855 rs61830900 chr10:871481 C/G cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs2072499 0.838 rs2758619 chr1:156162559 A/G cg24450063 chr1:156163899 SLC25A44 1.19 17.21 0.84 1.15e-34 Testicular germ cell tumor; TGCT cis rs611744 0.901 rs639746 chr8:109234825 T/C cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs7208859 0.573 rs11654035 chr17:29136426 T/C cg14008862 chr17:28927542 LRRC37B2 0.77 4.61 0.38 9.76e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs28595532 0.920 rs114581578 chr4:119756404 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs9296092 0.538 rs5000098 chr6:33519231 T/G cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs6951245 0.554 rs11544331 chr7:1131411 C/T cg18402987 chr7:1209562 NA 0.48 4.79 0.39 4.72e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2836974 0.897 rs35386515 chr21:40532047 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.57 0.65 1.43e-16 Cognitive function; TGCT cis rs959260 0.528 rs9909443 chr17:73308346 C/T cg14668889 chr17:73230827 NUP85 0.21 4.49 0.37 1.61e-5 Systemic lupus erythematosus; TGCT cis rs1949733 1.000 rs3103071 chr4:8508579 C/G cg11789530 chr4:8429930 ACOX3 -0.63 -5.82 -0.46 4.82e-8 Response to antineoplastic agents; TGCT cis rs259282 0.524 rs731674 chr19:33132395 A/G cg26639809 chr19:33781782 NA 0.21 4.45 0.37 1.93e-5 Schizophrenia; TGCT cis rs7923609 0.783 rs7100409 chr10:65330195 T/A cg08743896 chr10:65200160 JMJD1C 0.32 4.46 0.37 1.82e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs16939607 0.908 rs6997505 chr8:79004739 C/A cg21244580 chr8:79934476 NA 0.47 4.71 0.39 6.52e-6 White blood cell count; TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg01577475 chr2:114033581 PAX8;LOC440839 -0.45 -4.93 -0.41 2.54e-6 Lymphocyte counts; TGCT cis rs1865760 0.865 rs1115920 chr6:25954027 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.64 6.29 0.49 4.91e-9 Height; TGCT cis rs12049351 0.774 rs2381108 chr1:229637881 T/G cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs910316 0.967 rs4899550 chr14:75647666 C/T cg08847533 chr14:75593920 NEK9 -0.91 -9.96 -0.67 1.56e-17 Height; TGCT cis rs72781680 0.898 rs72780188 chr2:24006065 G/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs9443645 0.901 rs9361460 chr6:79589467 C/G cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs7474896 0.537 rs598857 chr10:38302926 A/G cg13720705 chr10:37990370 NA -0.35 -4.73 -0.39 5.99e-6 Obesity (extreme); TGCT cis rs1894292 0.527 rs4267703 chr4:74375921 T/C cg05868023 chr4:75230803 EREG 0.56 5.05 0.41 1.56e-6 Prostate cancer; TGCT cis rs477895 0.838 rs11605738 chr11:64013406 G/A cg04317338 chr11:64019027 PLCB3 0.81 6.9 0.53 2.35e-10 Mean platelet volume; TGCT cis rs9916302 0.904 rs11867312 chr17:37597748 C/T cg07936489 chr17:37558343 FBXL20 -0.61 -4.82 -0.4 4.16e-6 Glomerular filtration rate (creatinine); TGCT cis rs2688608 0.530 rs71507081 chr10:75493136 G/A cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT trans rs7618501 1.000 rs7372730 chr3:49790682 C/G cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs7246657 0.765 rs7247259 chr19:37851090 T/C cg03233940 chr19:37894644 NA -0.34 -4.49 -0.37 1.59e-5 Coronary artery calcification; TGCT cis rs1949733 1.000 rs2140337 chr4:8502112 A/G cg11789530 chr4:8429930 ACOX3 0.64 5.95 0.47 2.52e-8 Response to antineoplastic agents; TGCT cis rs10057188 1.000 rs6886783 chr5:77843876 C/T cg06873401 chr5:77792105 LHFPL2 -0.25 -4.93 -0.41 2.53e-6 Pulse pressure; TGCT cis rs13191362 1.000 rs13218900 chr6:163081638 T/C cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.97 0.53 1.69e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2836974 0.568 rs377098 chr21:40535216 G/A cg11890956 chr21:40555474 PSMG1 -0.76 -7.45 -0.56 1.36e-11 Cognitive function; TGCT cis rs68170813 0.559 rs74774133 chr7:106941449 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs514406 0.861 rs562182 chr1:53270010 C/T cg16325326 chr1:53192061 ZYG11B 0.73 9.0 0.63 3.34e-15 Monocyte count; TGCT cis rs34779708 0.897 rs9787566 chr10:35279455 T/A cg04310649 chr10:35416472 CREM -0.51 -4.55 -0.38 1.24e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs4664308 0.905 rs7567781 chr2:160999537 A/G cg03641300 chr2:160917029 PLA2R1 -0.27 -6.74 -0.52 5.42e-10 Idiopathic membranous nephropathy; TGCT cis rs34014631 1.000 rs116564386 chr10:103583355 T/C cg22630918 chr10:102748988 C10orf2 0.43 4.83 0.4 3.98e-6 Coronary artery calcification; TGCT cis rs3020333 0.846 rs3020335 chr6:152013223 G/T cg22157087 chr6:152012887 ESR1 0.19 4.58 0.38 1.1e-5 Total body bone mineral density; TGCT cis rs7845219 0.525 rs7820818 chr8:95919231 G/A cg16049864 chr8:95962084 TP53INP1 -0.51 -5.45 -0.44 2.56e-7 Type 2 diabetes; TGCT cis rs2239547 0.522 rs2710345 chr3:52976075 T/C cg10802521 chr3:52805072 NEK4 0.64 6.1 0.48 1.24e-8 Schizophrenia; TGCT trans rs10506458 0.915 rs12426308 chr12:63405778 C/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.52 -0.56 9.68e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs2235642 0.928 rs1057610 chr16:1605537 T/C cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.47 -0.44 2.39e-7 Coronary artery disease; TGCT cis rs9640161 0.830 rs3757424 chr7:150067679 C/A cg10018233 chr7:150070692 REPIN1 0.4 6.51 0.5 1.68e-9 Blood protein levels;Circulating chemerin levels; TGCT cis rs2820315 0.867 rs2820317 chr1:201878537 G/C cg12730843 chr1:201915899 LMOD1 -0.28 -5.13 -0.42 1.07e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs910316 0.967 rs175432 chr14:75615246 C/G cg11812906 chr14:75593930 NEK9 -0.76 -7.27 -0.55 3.45e-11 Height; TGCT cis rs8077889 0.917 rs6503479 chr17:41917003 A/G cg26893861 chr17:41843967 DUSP3 1.1 12.37 0.74 2.15e-23 Triglycerides; TGCT cis rs12510870 0.599 rs7676870 chr4:74449722 C/T cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg15659132 chr6:26577336 NA 0.85 10.79 0.7 1.54e-19 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.920 rs116105567 chr4:119746204 C/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs62380364 0.565 rs617944 chr5:88057915 T/C cg24804195 chr5:87968844 LOC645323 -0.55 -5.34 -0.43 4.23e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs73607863 chr8:58170178 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs115712871 chr4:98954535 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs236907 0.814 rs6695933 chr1:171774239 A/C cg20598894 chr1:171756153 METTL13 -0.2 -4.59 -0.38 1.07e-5 Mean platelet volume; TGCT cis rs9311474 0.508 rs4687546 chr3:52605943 T/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs55823223 0.702 rs3785437 chr17:73906222 G/T cg10935138 chr17:73851978 WBP2 1.02 6.29 0.49 5.06e-9 Psoriasis; TGCT cis rs17102423 0.731 rs10143198 chr14:65555471 C/T cg11161011 chr14:65562177 MAX -0.43 -5.91 -0.47 3.04e-8 Obesity-related traits; TGCT cis rs11577318 0.579 rs11247934 chr1:26695758 A/T cg15090202 chr1:26687087 NA 0.58 4.43 0.37 2.01e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2439831 0.681 rs540031 chr15:43608855 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.91 6.75 0.52 4.98e-10 Lung cancer in ever smokers; TGCT cis rs61990749 0.597 rs117131659 chr14:78131126 C/T cg02301378 chr14:78227641 SNW1;C14orf178 -0.61 -4.45 -0.37 1.89e-5 Fibroblast growth factor basic levels; TGCT cis rs769267 0.896 rs11882123 chr19:19386339 A/G cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs13256369 1.000 rs883648 chr8:8569521 A/G cg06671706 chr8:8559999 CLDN23 0.34 4.57 0.38 1.18e-5 Obesity-related traits; TGCT cis rs28595532 0.920 rs115860482 chr4:119759546 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs62380364 0.727 rs304137 chr5:88169652 A/G cg22951263 chr5:87985283 NA 0.5 5.02 0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs13108904 0.905 rs1680074 chr4:1279621 G/A cg03303774 chr4:1407052 NA -0.32 -4.88 -0.4 3.21e-6 Obesity-related traits; TGCT cis rs2242194 0.816 rs2242193 chr1:154995503 A/G cg24348479 chr1:155007323 DCST1;DCST2 -0.27 -5.72 -0.46 7.46e-8 Schizophrenia; TGCT cis rs6754311 0.589 rs11681659 chr2:136820960 C/T cg07169764 chr2:136633963 MCM6 -0.56 -5.5 -0.44 2.08e-7 Mosquito bite size; TGCT cis rs9457247 1.000 rs376574 chr6:167389956 A/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs28595532 0.920 rs116739193 chr4:119771024 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs13177918 0.626 rs13170300 chr5:149829311 G/A cg14059543 chr5:149831962 NA -0.69 -9.27 -0.64 7.32e-16 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs35883536 0.935 rs1577510 chr1:101114295 G/A cg06223162 chr1:101003688 GPR88 -0.29 -4.79 -0.4 4.61e-6 Monocyte count; TGCT cis rs9911578 1.000 rs302848 chr17:56686454 C/T cg12560992 chr17:57184187 TRIM37 0.74 9.71 0.66 6.46e-17 Intelligence (multi-trait analysis); TGCT cis rs5769707 0.609 rs135861 chr22:49998118 A/G cg05373962 chr22:49881684 NA -0.3 -5.16 -0.42 9.59e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2070488 0.775 rs6599207 chr3:38554901 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.73 -7.01 -0.53 1.37e-10 Electrocardiographic conduction measures; TGCT cis rs752092 0.894 rs8043243 chr15:101771453 C/T cg25114630 chr15:101792522 CHSY1 0.49 4.47 0.37 1.74e-5 Corneal structure; TGCT cis rs9611519 0.780 rs9611527 chr22:41644428 G/A cg06634786 chr22:41940651 POLR3H -0.58 -5.32 -0.43 4.77e-7 Neuroticism; TGCT cis rs3008870 0.755 rs2815364 chr1:67498384 C/T cg11518657 chr1:67396239 MIER1 0.47 4.61 0.38 9.68e-6 Lymphocyte percentage of white cells; TGCT cis rs4664308 1.000 rs10929965 chr2:160906931 C/T cg03641300 chr2:160917029 PLA2R1 0.26 6.53 0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs35160687 0.640 rs13015186 chr2:86485578 A/G cg03171300 chr2:86307199 POLR1A 0.32 5.35 0.43 4.05e-7 Night sleep phenotypes; TGCT cis rs3806843 0.547 rs246065 chr5:140323638 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs9916302 0.904 rs8079303 chr17:37530755 G/C cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs2721195 0.845 rs2721150 chr8:145724973 C/G cg15320075 chr8:145703422 NA 0.7 6.8 0.52 3.84e-10 Age at first birth; TGCT cis rs9660180 0.967 rs6603803 chr1:1812688 A/G cg03396347 chr1:1875803 NA -0.38 -6.89 -0.53 2.45e-10 Body mass index; TGCT cis rs7216064 0.589 rs8072723 chr17:66056970 T/A cg12091567 chr17:66097778 LOC651250 1.17 9.62 0.65 1.04e-16 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2832191 0.791 rs7283853 chr21:30498515 G/A cg08807101 chr21:30365312 RNF160 -0.62 -5.8 -0.46 5.14e-8 Dental caries; TGCT cis rs45535039 0.506 rs2511856 chr11:119144148 A/C cg16724696 chr11:118992527 HINFP -0.68 -6.0 -0.47 2.06e-8 Plateletcrit; TGCT cis rs8070740 0.786 rs8067738 chr17:5328661 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.49 4.49 0.37 1.63e-5 Menopause (age at onset); TGCT cis rs1129187 0.818 rs9462858 chr6:42946490 C/A cg17345569 chr6:42928274 GNMT -0.43 -4.43 -0.37 2.01e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9436747 0.641 rs10493379 chr1:66045927 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.58 5.22 0.42 7.22e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs739496 0.512 rs6489793 chr12:112249884 T/G cg10833066 chr12:111807467 FAM109A 0.38 5.67 0.45 9.69e-8 Platelet count; TGCT cis rs11783469 0.524 rs17089281 chr8:23335151 T/C cg00472375 chr8:23315376 ENTPD4 0.67 5.08 0.41 1.37e-6 Reticulocyte count; TGCT cis rs6933660 0.800 rs13201167 chr6:151773504 T/C cg17179660 chr6:151773299 C6orf211;RMND1 -0.54 -4.89 -0.4 3.1e-6 Menarche (age at onset); TGCT cis rs9325144 0.554 rs7960616 chr12:39096664 T/A cg26384229 chr12:38710491 ALG10B -0.55 -5.16 -0.42 9.52e-7 Morning vs. evening chronotype; TGCT cis rs12477438 0.700 rs12467679 chr2:99654449 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs6740322 1.000 rs4128209 chr2:43554729 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.32 -0.49 4.21e-9 Coronary artery disease; TGCT cis rs10464366 0.544 rs12668821 chr7:39167846 T/A cg15212455 chr7:39170539 POU6F2 0.3 6.63 0.51 9.08e-10 IgG glycosylation; TGCT cis rs910187 0.678 rs3818008 chr20:45816488 C/T cg27589058 chr20:45804311 EYA2 -0.35 -7.58 -0.56 7.14e-12 Migraine; TGCT cis rs2153535 0.580 rs9393025 chr6:8490618 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs17102423 0.594 rs1270074 chr14:65564856 T/C cg11161011 chr14:65562177 MAX -0.47 -6.42 -0.5 2.65e-9 Obesity-related traits; TGCT cis rs896854 0.738 rs527234 chr8:95963798 C/G cg16049864 chr8:95962084 TP53INP1 0.63 7.6 0.56 6.45e-12 Type 2 diabetes; TGCT cis rs736408 0.522 rs6445535 chr3:52771468 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs9486719 1.000 rs12208124 chr6:97027942 C/T cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs7714584 1.000 rs11167520 chr5:150265639 T/C cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs3784262 1.000 rs3784262 chr15:58253106 T/C cg12031962 chr15:58353849 ALDH1A2 -0.49 -7.67 -0.57 4.27e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs909002 0.800 rs7549590 chr1:32109849 G/A cg11573219 chr1:32083031 HCRTR1 -0.42 -5.41 -0.44 3.18e-7 Intelligence (multi-trait analysis); TGCT cis rs1395 0.848 rs6716850 chr2:27525350 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.49 6.41 0.5 2.71e-9 Blood metabolite levels; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg11905131 chr22:24372483 LOC391322 0.66 5.2 0.42 7.88e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs13108904 0.539 rs13145722 chr4:1338422 T/A cg13395646 chr4:1353034 KIAA1530 -0.55 -7.57 -0.56 7.56e-12 Obesity-related traits; TGCT cis rs40363 0.645 rs6501177 chr16:3523681 C/T cg00484396 chr16:3507460 NAT15 0.43 6.52 0.51 1.62e-9 Tuberculosis; TGCT cis rs1577917 1.000 rs791856 chr6:86681841 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.64 5.1 0.42 1.22e-6 Response to antipsychotic treatment; TGCT trans rs12599106 0.770 rs12445057 chr16:34970274 C/G cg18110333 chr6:292329 DUSP22 -0.72 -7.63 -0.57 5.43e-12 Menopause (age at onset); TGCT cis rs4478858 0.698 rs6669381 chr1:31833506 A/G cg07478791 chr1:31886160 SERINC2 -0.51 -4.93 -0.41 2.55e-6 Alcohol dependence; TGCT cis rs7772486 0.686 rs1011596 chr6:146076433 A/G cg13319975 chr6:146136371 FBXO30 -0.53 -4.65 -0.39 8.25e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6912958 0.781 rs9450723 chr6:88226641 C/T cg06598631 chr6:88300029 RARS2;ORC3L 0.5 4.65 0.39 8.23e-6 Monocyte percentage of white cells; TGCT cis rs2013441 1.000 rs34089239 chr17:20057959 G/T cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs10872587 0.657 rs11155459 chr6:146578751 A/G cg05347473 chr6:146136440 FBXO30 -0.6 -4.68 -0.39 7.54e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12540874 0.698 rs10899736 chr7:50546925 C/T cg18232548 chr7:50535776 DDC -0.37 -6.77 -0.52 4.49e-10 Systemic sclerosis; TGCT cis rs1245541 0.595 rs1668155 chr10:73858139 T/C cg10983208 chr10:73848320 SPOCK2 -0.26 -4.45 -0.37 1.88e-5 Insulin-like growth factors; TGCT cis rs61008539 0.815 rs6960062 chr7:884665 A/G cg00475322 chr7:917719 C7orf20 0.55 7.95 0.58 9.94e-13 Perceived unattractiveness to mosquitoes; TGCT cis rs7681440 0.904 rs12331318 chr4:90770255 A/G cg20003494 chr4:90757398 SNCA -0.61 -5.75 -0.46 6.58e-8 Dementia with Lewy bodies; TGCT cis rs2153535 0.504 rs9405393 chr6:8467432 G/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs36051895 0.632 rs12001334 chr9:5152604 C/A cg02405213 chr9:5042618 JAK2 -0.75 -9.81 -0.66 3.66e-17 Pediatric autoimmune diseases; TGCT cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg12311346 chr5:56204834 C5orf35 -0.66 -6.37 -0.5 3.3e-9 Initial pursuit acceleration; TGCT cis rs7845219 0.539 rs713113 chr8:95877787 C/T cg13393036 chr8:95962371 TP53INP1 0.49 5.95 0.47 2.55e-8 Type 2 diabetes; TGCT cis rs6598955 0.543 rs60433268 chr1:26548055 A/C cg04990556 chr1:26633338 UBXN11 0.8 7.3 0.55 3.01e-11 Obesity-related traits; TGCT cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs2120019 1.000 rs60425110 chr15:75333000 T/A cg09165964 chr15:75287851 SCAMP5 -1.14 -10.22 -0.68 3.76e-18 Blood trace element (Zn levels); TGCT cis rs6666258 1.000 rs13376333 chr1:154814353 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.59 -4.83 -0.4 3.97e-6 Atrial fibrillation; TGCT cis rs62064224 0.614 rs4794921 chr17:30742310 C/T cg18200150 chr17:30822561 MYO1D 0.39 4.71 0.39 6.52e-6 Schizophrenia; TGCT cis rs514406 0.825 rs497535 chr1:53284677 A/G cg08736216 chr1:53307985 ZYG11A 0.25 4.93 0.4 2.59e-6 Monocyte count; TGCT cis rs6589563 0.737 rs57200947 chr11:116623674 C/T cg01124546 chr11:117515332 DSCAML1 -0.44 -4.77 -0.39 5.18e-6 Eosinophil counts; TGCT cis rs6088580 0.634 rs3736762 chr20:33037336 C/T cg08999081 chr20:33150536 PIGU 0.29 5.67 0.45 9.68e-8 Glomerular filtration rate (creatinine); TGCT cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg05738196 chr6:26577821 NA 0.87 10.44 0.68 1.08e-18 Intelligence (multi-trait analysis); TGCT cis rs319204 0.843 rs319160 chr5:146300571 T/C cg25021259 chr5:146258546 PPP2R2B 0.37 4.59 0.38 1.06e-5 Schizophrenia; TGCT cis rs28595532 0.844 rs115202072 chr4:119732458 C/T cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs36051895 0.632 rs7036536 chr9:5181610 T/C cg02405213 chr9:5042618 JAK2 -0.76 -10.76 -0.69 1.8e-19 Pediatric autoimmune diseases; TGCT cis rs9902453 0.817 rs67206808 chr17:28190096 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.79 7.15 0.54 6.65e-11 Coffee consumption (cups per day); TGCT cis rs6951245 1.000 rs76214082 chr7:1102097 T/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2153535 0.623 rs2152346 chr6:8454652 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs4919694 1.000 rs78214351 chr10:104822688 A/G cg04362960 chr10:104952993 NT5C2 1.07 7.09 0.54 8.9e-11 Arsenic metabolism; TGCT cis rs6141769 0.542 rs28536730 chr20:31301954 A/C cg13636640 chr20:31349939 DNMT3B -0.51 -4.48 -0.37 1.68e-5 Subjective well-being; TGCT cis rs1775715 0.737 rs2799031 chr10:32173168 C/T cg14930904 chr10:32216787 ARHGAP12 0.54 5.3 0.43 5.12e-7 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs514406 0.861 rs11206026 chr1:53281708 G/A cg08859206 chr1:53392774 SCP2 -0.38 -5.68 -0.45 8.95e-8 Monocyte count; TGCT cis rs478304 0.651 rs948493 chr11:65552154 C/T cg17480646 chr11:65405466 SIPA1 -0.55 -6.45 -0.5 2.25e-9 Acne (severe); TGCT cis rs9611519 1.000 rs5758264 chr22:41616284 T/G cg03806693 chr22:41940476 POLR3H -0.66 -6.3 -0.49 4.65e-9 Neuroticism; TGCT cis rs7296418 0.961 rs10773921 chr12:123541606 C/T cg00376283 chr12:123451042 ABCB9 0.81 7.38 0.55 2.03e-11 Platelet count; TGCT cis rs71636778 0.509 rs12752711 chr1:27250258 G/C cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs514406 0.661 rs562641 chr1:53374666 C/T cg16325326 chr1:53192061 ZYG11B 0.5 5.56 0.45 1.56e-7 Monocyte count; TGCT cis rs4819052 0.851 rs34101026 chr21:46662200 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9611565 0.512 rs7291736 chr22:42124874 C/A cg13695892 chr22:41940480 POLR3H 0.88 8.63 0.61 2.45e-14 Vitiligo; TGCT cis rs931127 0.502 rs1466462 chr11:65419364 C/G cg27068330 chr11:65405492 SIPA1 1.01 11.9 0.73 3.05e-22 Systemic lupus erythematosus; TGCT cis rs9611565 0.592 rs5996038 chr22:41965300 T/C cg17554472 chr22:41940697 POLR3H -0.48 -4.94 -0.41 2.47e-6 Vitiligo; TGCT cis rs9916302 0.784 rs4795382 chr17:37700860 A/G cg07936489 chr17:37558343 FBXL20 -0.61 -4.87 -0.4 3.29e-6 Glomerular filtration rate (creatinine); TGCT trans rs551517 0.541 rs575638 chr9:113639333 C/T cg18410444 chr5:89825535 LYSMD3 0.67 6.77 0.52 4.49e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs6901250 1.000 rs6924002 chr6:117114223 A/T cg12892004 chr6:117198278 RFX6 0.46 5.23 0.43 6.85e-7 C-reactive protein levels; TGCT trans rs4650994 1.000 rs4354501 chr1:178524596 T/C cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.37e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9916302 0.898 rs8072297 chr17:37478048 A/T cg15445000 chr17:37608096 MED1 -0.33 -4.61 -0.38 9.9e-6 Glomerular filtration rate (creatinine); TGCT cis rs7582180 0.614 rs4340543 chr2:101005511 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.77 -0.39 5.16e-6 Intelligence (multi-trait analysis); TGCT cis rs12220898 0.679 rs10776555 chr10:50484995 A/G cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs9611565 0.659 rs73178626 chr22:41928371 T/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs9916302 0.752 rs676882 chr17:37433424 A/T cg07936489 chr17:37558343 FBXL20 0.94 6.14 0.48 1.02e-8 Glomerular filtration rate (creatinine); TGCT cis rs7226408 0.842 rs72883593 chr18:34390840 G/A cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs7917772 0.582 rs11191352 chr10:104372244 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3820068 0.581 rs74054797 chr1:15926217 G/A cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs909674 0.865 rs5757683 chr22:39850174 G/A cg24399712 chr22:39784796 NA -1.05 -11.23 -0.71 1.25e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4888262 0.526 rs8055803 chr16:74615190 A/G cg01733217 chr16:74700730 RFWD3 0.75 7.54 0.56 8.8e-12 Testicular germ cell tumor; TGCT cis rs12681288 0.862 rs2600487 chr8:1016903 C/T cg21347738 chr8:1310380 NA -0.22 -4.44 -0.37 1.93e-5 Schizophrenia; TGCT cis rs7014346 0.767 rs12678562 chr8:128422488 A/G cg04263511 chr8:128962092 PVT1 -0.31 -4.5 -0.37 1.54e-5 Colorectal cancer; TGCT trans rs2469997 1.000 rs2469998 chr8:120354022 G/A cg01792902 chr3:178864926 PIK3CA 0.78 6.66 0.51 7.93e-10 Hypertension (SNP x SNP interaction); TGCT cis rs12142240 0.698 rs72677585 chr1:46812374 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.79 -0.4 4.68e-6 Menopause (age at onset); TGCT cis rs77741769 0.529 rs909053 chr12:121237668 G/A cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs910316 0.763 rs175435 chr14:75612025 A/G cg11812906 chr14:75593930 NEK9 0.63 5.82 0.46 4.69e-8 Height; TGCT cis rs2439831 0.867 rs935901 chr15:43651256 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 5.28 0.43 5.66e-7 Lung cancer in ever smokers; TGCT cis rs611744 0.538 rs13257548 chr8:109273185 G/A cg21045802 chr8:109455806 TTC35 0.82 8.65 0.61 2.19e-14 Dupuytren's disease; TGCT trans rs1005277 0.579 rs2504140 chr10:38387579 T/G cg27523141 chr10:43048294 ZNF37B 0.73 8.58 0.61 3.32e-14 Extrinsic epigenetic age acceleration; TGCT cis rs1153858 1.000 rs1554521 chr15:45664189 A/T cg14582100 chr15:45693742 SPATA5L1 -0.51 -5.99 -0.47 2.12e-8 Homoarginine levels; TGCT cis rs9733 0.527 rs11204694 chr1:150653391 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.71 0.39 6.57e-6 Tonsillectomy; TGCT cis rs9990333 0.562 rs55970879 chr3:195821966 G/A cg14488913 chr3:195402182 SDHAP2 -0.36 -4.6 -0.38 1.03e-5 Iron status biomarkers (transferrin levels);Iron status biomarkers (transferrin saturation); TGCT cis rs4808199 0.948 rs7250368 chr19:19452763 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.48 0.44 2.24e-7 Nonalcoholic fatty liver disease; TGCT cis rs875971 0.898 rs6977501 chr7:65693342 T/C cg18876405 chr7:65276391 NA -0.32 -4.92 -0.4 2.72e-6 Aortic root size; TGCT cis rs1034435 0.755 rs6007869 chr22:48894213 A/G cg05992904 chr22:48892994 FAM19A5 -0.33 -4.53 -0.38 1.37e-5 Late-onset Alzheimer's disease; TGCT cis rs7523273 0.597 rs4844620 chr1:207980901 C/T cg22525895 chr1:207977042 MIR29B2 -0.44 -6.28 -0.49 5.18e-9 Schizophrenia; TGCT cis rs7523050 0.730 rs11102650 chr1:109464228 C/G cg08274380 chr1:109419600 GPSM2 1.27 6.86 0.52 2.9e-10 Fat distribution (HIV); TGCT cis rs35306767 0.903 rs11253488 chr10:922482 G/C cg26597838 chr10:835615 NA 0.75 10.54 0.69 6.3e-19 Eosinophil percentage of granulocytes; TGCT cis rs9393777 0.720 rs56874662 chr6:26985607 C/A cg16898833 chr6:26189333 HIST1H4D 0.97 5.95 0.47 2.6e-8 Intelligence (multi-trait analysis); TGCT cis rs4325129 1.000 rs12133664 chr1:159460890 C/T cg20944283 chr1:159172620 CADM3 -0.28 -4.44 -0.37 1.96e-5 Obesity-related traits; TGCT cis rs7811142 1.000 rs6975729 chr7:100028187 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs2242116 0.760 rs4682845 chr3:46955404 G/C cg23352942 chr3:46931381 PTH1R -0.34 -4.97 -0.41 2.19e-6 Birth weight; TGCT cis rs7618915 0.571 rs12632381 chr3:52607685 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs7666738 0.719 rs4699323 chr4:98967484 G/A cg17366294 chr4:99064904 C4orf37 0.69 4.96 0.41 2.23e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs6976053 0.818 rs13241786 chr7:100486656 T/G cg03880458 chr7:100306854 NA 0.17 4.51 0.38 1.47e-5 Plasminogen activator inhibitor type 1 levels (PAI-1); TGCT cis rs17030434 1.000 rs12651051 chr4:154722114 A/G cg14289246 chr4:154710475 SFRP2 -0.91 -7.2 -0.54 5.18e-11 Electrocardiographic conduction measures; TGCT cis rs4665809 0.838 rs6546749 chr2:26306288 T/C cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs651907 0.535 rs11711903 chr3:101500748 C/G cg11279151 chr3:101281821 RG9MTD1 -0.29 -6.22 -0.49 6.91e-9 Colorectal cancer; TGCT cis rs7552404 1.000 rs11161521 chr1:76216330 T/C cg22875332 chr1:76189707 ACADM 0.76 9.2 0.64 1.1e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9527 0.590 rs10883829 chr10:104840635 T/C cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT cis rs763014 0.966 rs7198877 chr16:661439 A/G cg27436995 chr16:743998 FBXL16 -0.45 -4.92 -0.4 2.64e-6 Height; TGCT cis rs72843506 0.722 rs9908032 chr17:20108184 C/G cg18979559 chr17:20280153 CCDC144C -0.65 -4.89 -0.4 3.07e-6 Schizophrenia; TGCT cis rs13064411 0.696 rs7622740 chr3:113206771 G/A cg18753928 chr3:113234510 CCDC52 -0.69 -5.57 -0.45 1.47e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs1577917 1.000 rs6923148 chr6:86767786 A/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.67 5.5 0.44 2.05e-7 Response to antipsychotic treatment; TGCT cis rs2439831 0.867 rs11856184 chr15:43919162 A/C cg27015174 chr15:43622946 ADAL;LCMT2 0.73 4.95 0.41 2.38e-6 Lung cancer in ever smokers; TGCT cis rs7089973 0.604 rs11196937 chr10:116589500 G/C cg03647239 chr10:116582469 FAM160B1 0.59 5.75 0.46 6.46e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs13217239 0.646 rs12523820 chr6:27001502 A/G cg26531700 chr6:26746687 NA 0.68 6.86 0.52 2.83e-10 Schizophrenia; TGCT cis rs78456975 1.000 rs72776252 chr2:1525599 G/A cg01028140 chr2:1542097 TPO -0.36 -4.63 -0.38 9.02e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs6921919 0.515 rs1558205 chr6:28382262 A/C cg18815343 chr6:28367644 ZSCAN12 0.47 4.8 0.4 4.5e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg07157834 chr1:205819609 PM20D1 0.44 6.76 0.52 4.71e-10 Menarche (age at onset); TGCT cis rs7635838 0.892 rs6442252 chr3:11451416 T/C cg00170343 chr3:11313890 ATG7 0.65 6.15 0.48 9.98e-9 HDL cholesterol; TGCT cis rs7811142 0.830 rs6945952 chr7:99981775 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs524281 0.861 rs7941469 chr11:65900152 A/G cg00563793 chr11:65837595 PACS1 -0.55 -4.58 -0.38 1.13e-5 Electroencephalogram traits; TGCT cis rs6570726 0.791 rs7755253 chr6:145858893 C/G cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs13064411 0.696 rs1552432 chr3:113225660 G/C cg10517650 chr3:113235015 CCDC52 -0.32 -4.45 -0.37 1.85e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs208520 0.690 rs207102 chr6:66795671 G/A cg07460842 chr6:66804631 NA -0.94 -9.86 -0.66 2.74e-17 Exhaled nitric oxide output; TGCT cis rs1865760 0.593 rs2097273 chr6:25941310 A/C cg03517284 chr6:25882590 NA -0.48 -4.79 -0.4 4.65e-6 Height; TGCT cis rs10504229 1.000 rs112272435 chr8:58170371 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs5769765 0.908 rs138867 chr22:50207703 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.34 -5.04 -0.41 1.63e-6 Schizophrenia; TGCT cis rs9872999 1 rs9872999 chr3:133457514 C/T cg24879335 chr3:133465180 TF 0.36 4.86 0.4 3.46e-6 Iron status biomarkers; TGCT cis rs9916302 0.904 rs9944411 chr17:37483599 T/C cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs7095607 0.538 rs2255136 chr10:69921733 T/A cg18986048 chr10:69913749 MYPN 0.61 6.45 0.5 2.3e-9 Lung function (FVC); TGCT cis rs1577917 0.771 rs2783171 chr6:86382765 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 5.58 0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs17102423 0.755 rs7143495 chr14:65546361 C/T cg11161011 chr14:65562177 MAX 0.55 7.66 0.57 4.63e-12 Obesity-related traits; TGCT cis rs62103177 0.608 rs8088089 chr18:77832154 A/G cg07235805 chr18:78004237 PARD6G -0.51 -4.98 -0.41 2.11e-6 Opioid sensitivity; TGCT cis rs453301 0.657 rs36056437 chr8:8792865 T/G cg15556689 chr8:8085844 FLJ10661 -0.64 -5.4 -0.44 3.31e-7 Joint mobility (Beighton score); TGCT cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg18765753 chr7:1198926 ZFAND2A -0.5 -5.98 -0.47 2.18e-8 Longevity;Endometriosis; TGCT cis rs40363 0.672 rs1617722 chr16:3520806 C/T cg22508957 chr16:3507546 NAT15 -0.53 -6.17 -0.48 8.69e-9 Tuberculosis; TGCT cis rs9611565 0.512 rs6002474 chr22:42168181 A/G cg06634786 chr22:41940651 POLR3H 0.85 8.15 0.59 3.41e-13 Vitiligo; TGCT cis rs3771570 0.792 rs4675970 chr2:242200406 G/A cg21155796 chr2:242212141 HDLBP 0.86 6.43 0.5 2.53e-9 Prostate cancer; TGCT cis rs7020830 0.898 rs7857936 chr9:37078491 T/C cg14294708 chr9:37120828 ZCCHC7 1.21 17.76 0.85 7.18e-36 Schizophrenia; TGCT cis rs9303401 0.659 rs34878689 chr17:56694330 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs6952808 1.000 rs4721121 chr7:1892565 A/G cg22963979 chr7:1858916 MAD1L1 -0.34 -5.21 -0.42 7.6e-7 Bipolar disorder and schizophrenia; TGCT cis rs6582630 0.555 rs11182429 chr12:38526679 A/C cg26384229 chr12:38710491 ALG10B 0.85 7.84 0.58 1.81e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs2243480 1.000 rs6959002 chr7:65650496 A/G cg07424592 chr7:64974309 NA -1.27 -7.84 -0.58 1.8e-12 Diabetic kidney disease; TGCT trans rs7698623 0.702 rs4693884 chr4:88770229 C/T cg01186725 chr1:53905612 FLJ40434 0.48 6.63 0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs10114408 0.877 rs10992946 chr9:96642327 C/T cg13679303 chr9:96623674 NA -0.35 -4.45 -0.37 1.85e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs17443541 0.516 rs971324 chr2:200450386 A/G cg00055341 chr2:200446845 NA -0.37 -4.53 -0.38 1.35e-5 Intelligence (multi-trait analysis); TGCT cis rs11696501 0.739 rs6104249 chr20:44250487 C/G cg11783356 chr20:44313418 WFDC10B 0.35 4.99 0.41 1.97e-6 Brain structure; TGCT cis rs908922 0.676 rs2181172 chr1:152491794 A/G cg20991723 chr1:152506922 NA 0.46 6.28 0.49 5.16e-9 Hair morphology; TGCT cis rs9916302 0.768 rs11078900 chr17:37614641 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs9913156 0.793 rs55682338 chr17:4582183 G/A cg19197139 chr17:4613644 ARRB2 0.84 7.9 0.58 1.25e-12 Lymphocyte counts; TGCT cis rs6500602 0.673 rs4786512 chr16:4573040 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.44 7.88 0.58 1.4e-12 Schizophrenia; TGCT cis rs4629710 0.592 rs9492868 chr6:131542238 A/C cg12606694 chr6:131520996 AKAP7 0.39 4.63 0.38 9.14e-6 Multiple myeloma (IgH translocation); TGCT cis rs1372520 0.577 rs2737028 chr4:90717016 A/G cg15133208 chr4:90757351 SNCA -0.53 -6.14 -0.48 1.02e-8 Neuroticism; TGCT cis rs797680 0.821 rs7551485 chr1:93751280 G/A cg17826107 chr1:92977322 EVI5 0.23 5.11 0.42 1.2e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7582180 0.764 rs4635546 chr2:100921125 G/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.26 -0.43 6.1e-7 Intelligence (multi-trait analysis); TGCT cis rs9911578 0.933 rs11868348 chr17:57179238 C/T cg12560992 chr17:57184187 TRIM37 0.79 9.71 0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs9811920 0.515 rs792836 chr3:99476384 G/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.39 4.6 0.38 1.04e-5 Axial length; TGCT cis rs6121246 0.909 rs6058463 chr20:30385192 C/T cg18721089 chr20:30220636 NA -0.43 -4.75 -0.39 5.54e-6 Mean corpuscular hemoglobin; TGCT cis rs9787249 0.957 rs7518431 chr1:40214944 C/T cg20968010 chr1:40505947 CAP1 0.48 4.55 0.38 1.24e-5 Blood protein levels; TGCT cis rs9611519 0.780 rs1535048 chr22:41684093 C/T cg03806693 chr22:41940476 POLR3H -0.8 -7.66 -0.57 4.62e-12 Neuroticism; TGCT trans rs9388451 0.868 rs1268083 chr6:126049040 T/C cg05039488 chr6:79577232 IRAK1BP1 0.76 8.09 0.59 4.66e-13 Brugada syndrome; TGCT cis rs7044106 0.791 rs10760116 chr9:123494681 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.44 4.79 0.4 4.57e-6 Hip circumference adjusted for BMI; TGCT cis rs6879260 0.963 rs11748619 chr5:179727399 C/G cg23248424 chr5:179741104 GFPT2 -0.35 -6.32 -0.49 4.31e-9 Height; TGCT cis rs308403 0.568 rs13138520 chr4:123675483 C/G cg10495464 chr4:123653540 BBS12;LOC729338 0.7 6.48 0.5 1.9e-9 Blood protein levels; TGCT cis rs769267 0.930 rs7254748 chr19:19397479 A/C cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs6912958 0.781 rs9444504 chr6:88181046 A/C cg06598631 chr6:88300029 RARS2;ORC3L -0.52 -4.83 -0.4 3.92e-6 Monocyte percentage of white cells; TGCT cis rs13326165 0.760 rs11711934 chr3:52358117 T/C cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs5769707 0.839 rs73176988 chr22:49989649 G/T cg05373962 chr22:49881684 NA -0.3 -6.12 -0.48 1.12e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6975373 0.643 rs12540089 chr7:4446121 C/A cg10785373 chr7:4456119 NA 0.61 6.45 0.5 2.21e-9 Borderline personality disorder; TGCT cis rs2658782 0.756 rs3019223 chr11:93084182 G/A cg18152523 chr11:93063302 CCDC67 -0.67 -5.19 -0.42 8.29e-7 Pulmonary function decline; TGCT cis rs910316 1.000 rs175512 chr14:75523382 T/C cg11812906 chr14:75593930 NEK9 -0.73 -7.08 -0.54 9.26e-11 Height; TGCT cis rs425277 0.606 rs262653 chr1:2090095 T/G cg24578937 chr1:2090814 PRKCZ 0.26 6.95 0.53 1.8e-10 Height; TGCT cis rs28489187 0.558 rs2474123 chr1:85827452 C/T cg16011679 chr1:85725395 C1orf52 0.49 4.5 0.37 1.57e-5 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs3096299 0.967 rs2911257 chr16:89484134 C/G cg02187348 chr16:89574699 SPG7 0.46 4.52 0.38 1.45e-5 Multiple myeloma (IgH translocation); TGCT cis rs7267979 1.000 rs11087521 chr20:25440648 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs938554 0.513 rs3733588 chr4:9997303 A/G cg00071950 chr4:10020882 SLC2A9 -0.59 -5.84 -0.46 4.4e-8 Blood metabolite levels; TGCT cis rs6570726 0.935 rs419847 chr6:145827278 A/G cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7586879 0.616 rs13410999 chr2:25097939 T/C cg15423357 chr2:25149977 NA 0.46 4.47 0.37 1.72e-5 Body mass index; TGCT cis rs9788721 1.000 rs10519203 chr15:78814046 C/T cg18825076 chr15:78729989 IREB2 0.31 4.62 0.38 9.56e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs7914558 0.966 rs10786727 chr10:104698523 G/A cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4148883 0.645 rs1154404 chr4:100009004 A/T cg12011299 chr4:100065546 ADH4 0.39 5.85 0.47 4.01e-8 Alcohol dependence; TGCT cis rs6582630 0.502 rs4385963 chr12:38295264 G/A cg26384229 chr12:38710491 ALG10B 0.8 7.04 0.53 1.17e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs10089 1.000 rs10057122 chr5:127512063 T/C cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.79 7.63 0.57 5.42e-12 Ileal carcinoids; TGCT cis rs6671200 0.607 rs2147587 chr1:95714884 G/A cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs73198271 0.653 rs3827811 chr8:8659038 C/T cg06671706 chr8:8559999 CLDN23 -0.35 -4.59 -0.38 1.08e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9926296 0.557 rs11076618 chr16:89807705 T/C cg27121462 chr16:89883253 FANCA 0.55 5.05 0.41 1.57e-6 Vitiligo; TGCT cis rs7085104 0.684 rs7092690 chr10:104609365 T/C cg15744005 chr10:104629667 AS3MT -0.45 -5.8 -0.46 5.2e-8 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs1005224 0.853 rs61980778 chr14:76151532 C/T cg25116370 chr14:76127843 TTLL5;C14orf1 0.54 4.72 0.39 6.23e-6 Large artery stroke; TGCT cis rs28785552 0.536 rs7260576 chr19:53248626 G/T cg22067481 chr19:53234126 ZNF611 -0.44 -5.92 -0.47 2.99e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs6840360 0.642 rs1470281 chr4:152431552 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs11864453 0.578 rs2072141 chr16:72133211 G/A cg14768367 chr16:72042858 DHODH 0.52 5.27 0.43 5.78e-7 Fibrinogen levels; TGCT cis rs6793245 0.960 rs12053903 chr3:38593393 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.49 -4.71 -0.39 6.45e-6 QT interval; TGCT cis rs9443645 0.901 rs9352667 chr6:79572296 A/G cg09184832 chr6:79620586 NA 0.49 5.29 0.43 5.3e-7 Intelligence (multi-trait analysis); TGCT cis rs7726839 0.540 rs7434 chr5:660804 A/G cg09021430 chr5:549028 NA 0.38 5.32 0.43 4.74e-7 Obesity-related traits; TGCT cis rs7666738 0.791 rs11735105 chr4:98937357 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs1552244 1.000 rs67006488 chr3:10152993 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs250677 0.522 rs12523526 chr5:148349107 A/C cg18129178 chr5:148520854 ABLIM3 0.38 4.75 0.39 5.62e-6 Breast cancer; TGCT cis rs3885907 0.542 rs9670531 chr13:31321069 A/G cg22282089 chr13:30686841 NA -0.21 -4.49 -0.37 1.59e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+epirubicin+/-5FU); TGCT trans rs12599106 0.709 rs1501462 chr16:34964515 A/T cg01516881 chr6:292596 DUSP22 -0.79 -8.23 -0.59 2.24e-13 Menopause (age at onset); TGCT cis rs12477438 0.520 rs6708576 chr2:99801308 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 0.86 8.52 0.61 4.42e-14 Chronic sinus infection; TGCT cis rs9611565 0.512 rs139561 chr22:42195410 C/T cg03806693 chr22:41940476 POLR3H 0.98 10.13 0.67 6e-18 Vitiligo; TGCT cis rs8067545 1.000 rs2108979 chr17:19928566 G/A cg13482628 chr17:19912719 NA 0.53 4.48 0.37 1.66e-5 Schizophrenia; TGCT cis rs7584330 0.955 rs58643200 chr2:238389855 A/G cg14458575 chr2:238380390 NA 0.48 7.42 0.55 1.66e-11 Prostate cancer; TGCT cis rs2040771 0.872 rs12485084 chr22:19162326 A/G cg02655711 chr22:19163373 SLC25A1 0.24 4.58 0.38 1.11e-5 Metabolite levels (small molecules and protein measures); TGCT cis rs7914558 1.000 rs943036 chr10:104836047 T/C cg04362960 chr10:104952993 NT5C2 0.6 5.32 0.43 4.64e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17030434 0.953 rs76442373 chr4:154694783 G/A cg14289246 chr4:154710475 SFRP2 -0.95 -7.48 -0.56 1.18e-11 Electrocardiographic conduction measures; TGCT cis rs1757171 0.534 rs2797793 chr6:37477262 C/T cg01843034 chr6:37503916 NA 0.47 6.05 0.48 1.55e-8 Cognitive performance; TGCT cis rs7822232 0.908 rs6558295 chr8:145139522 C/G cg14631276 chr8:145163102 KIAA1875 -0.56 -5.05 -0.41 1.55e-6 Blood metabolite levels; TGCT cis rs1215050 0.791 rs260889 chr4:98742340 A/G cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs908922 0.676 rs12129646 chr1:152518816 C/T cg20991723 chr1:152506922 NA 0.44 5.99 0.47 2.13e-8 Hair morphology; TGCT cis rs2289681 0.583 rs2289674 chr17:42953409 A/G cg15193461 chr17:42977049 CCDC103;EFTUD2 -0.68 -5.75 -0.46 6.44e-8 Cognitive function; TGCT cis rs709400 1.000 rs6593 chr14:104163282 G/A cg26031613 chr14:104095156 KLC1 1.13 17.11 0.84 1.95e-34 Body mass index; TGCT cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.28 4.92 0.4 2.73e-6 Schizophrenia; TGCT cis rs9911578 1.000 rs12936058 chr17:57017420 T/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs42648 1.000 rs42656 chr7:89981636 A/G cg25739043 chr7:89950458 NA -0.67 -6.71 -0.52 6.07e-10 Homocysteine levels; TGCT cis rs2228479 0.850 rs11649162 chr16:89807131 C/A cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs10479542 0.683 rs7380706 chr5:178961872 C/T cg09060608 chr5:178986726 RUFY1 0.42 4.7 0.39 6.83e-6 Lung cancer; TGCT cis rs1008375 1.000 rs10939743 chr4:17662731 G/A cg10189774 chr4:17578691 LAP3 0.54 5.0 0.41 1.89e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs17331151 0.573 rs28552648 chr3:52865593 G/A cg12962167 chr3:53033115 SFMBT1 0.44 4.96 0.41 2.28e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3749237 0.964 rs35210174 chr3:49812606 C/T cg10152585 chr3:50297680 NA 0.5 4.65 0.39 8.38e-6 Resting heart rate; TGCT cis rs56104184 0.775 rs17272707 chr19:49404535 T/G cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs3091242 0.933 rs10903129 chr1:25768937 A/G cg09222892 chr1:25734099 RHCE -0.42 -7.15 -0.54 6.67e-11 Erythrocyte sedimentation rate; TGCT cis rs9467773 0.620 rs2494696 chr6:26620894 A/G cg02458000 chr6:26745757 NA 0.55 5.25 0.43 6.28e-7 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.583 rs2410124 chr21:40704760 C/G cg17971929 chr21:40555470 PSMG1 -0.69 -6.0 -0.47 1.97e-8 Cognitive function; TGCT cis rs10254284 0.921 rs2391591 chr7:28157664 G/T cg23620719 chr7:28220237 JAZF1 -0.55 -4.85 -0.4 3.67e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs6714710 0.603 rs4311104 chr2:98424802 A/G cg26665480 chr2:98280029 ACTR1B 0.66 6.24 0.49 6.33e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs477895 1.000 rs66968227 chr11:64070930 T/C cg04317338 chr11:64019027 PLCB3 0.68 5.33 0.43 4.39e-7 Mean platelet volume; TGCT cis rs734999 0.588 rs60520190 chr1:2533706 G/A cg18854424 chr1:2615690 NA 0.44 5.1 0.42 1.22e-6 Ulcerative colitis; TGCT cis rs6725041 0.819 rs1521644 chr2:213091246 A/G cg20637307 chr2:213403960 ERBB4 -0.52 -4.6 -0.38 1.02e-5 QT interval (ambient particulate matter interaction); TGCT cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs10779751 1.000 rs12032364 chr1:11286872 G/T cg08854313 chr1:11322531 MTOR 0.96 8.74 0.62 1.37e-14 Body mass index; TGCT trans rs7819412 0.774 rs34208825 chr8:11014616 T/G cg15556689 chr8:8085844 FLJ10661 -0.83 -7.48 -0.56 1.18e-11 Triglycerides; TGCT cis rs5769765 0.908 rs9627788 chr22:50300438 T/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.08 -10.42 -0.68 1.19e-18 Schizophrenia; TGCT cis rs2050392 0.928 rs6481677 chr10:30701816 A/G cg18806716 chr10:30721971 MAP3K8 -0.45 -5.32 -0.43 4.66e-7 Inflammatory bowel disease; TGCT cis rs28595532 0.920 rs114080496 chr4:119726372 C/T cg21605333 chr4:119757512 SEC24D 1.72 8.96 0.63 3.99e-15 Cannabis dependence symptom count; TGCT cis rs9303401 0.659 rs35103007 chr17:56900738 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs2721195 0.845 rs1063739 chr8:145729727 C/A cg15320075 chr8:145703422 NA 0.68 6.6 0.51 1.05e-9 Age at first birth; TGCT cis rs9948 0.529 rs62156208 chr2:97383686 A/G cg01990225 chr2:97406019 LMAN2L -1.01 -5.13 -0.42 1.08e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs116095464 0.558 rs7715108 chr5:264661 A/G cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs67478160 0.643 rs2024667 chr14:104211529 T/G cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs9660180 0.868 rs72634846 chr1:1704915 C/G cg17747265 chr1:1875780 NA -0.38 -7.18 -0.54 5.67e-11 Body mass index; TGCT cis rs17268829 1.000 rs10273041 chr7:94087489 C/T cg06439941 chr7:93550756 GNG11 -0.24 -4.49 -0.37 1.62e-5 Breast cancer; TGCT cis rs7516138 1.000 rs4240895 chr1:9713386 C/T cg26573321 chr1:9711663 PIK3CD 0.37 4.48 0.37 1.71e-5 Monocyte count; TGCT cis rs2115630 0.645 rs3825877 chr15:85174631 G/A cg17173187 chr15:85201210 NMB -0.48 -5.78 -0.46 5.69e-8 P wave terminal force; TGCT cis rs427394 0.802 rs274718 chr5:6720988 G/T cg10857441 chr5:6722123 POLS -0.33 -8.05 -0.59 5.7e-13 Menopause (age at onset); TGCT cis rs2562456 0.754 rs55771551 chr19:21746380 C/T cg01304269 chr19:21688519 ZNF429 0.58 4.73 0.39 5.93e-6 Pain; TGCT cis rs10504229 0.906 rs7846666 chr8:58172302 T/C cg21724239 chr8:58056113 NA 0.33 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs7209700 0.821 rs2292863 chr17:45369130 C/G cg21624342 chr17:45890973 OSBPL7 0.19 5.09 0.42 1.32e-6 IgG glycosylation; TGCT cis rs3806843 1.000 rs991918 chr5:140194858 C/T cg19875535 chr5:140030758 IK 0.35 5.71 0.46 7.94e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs936229 0.813 rs72730503 chr15:75086386 G/A cg10253484 chr15:75165896 SCAMP2 -0.63 -4.95 -0.41 2.33e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg26224354 chr7:1096374 C7orf50;GPR146 -0.31 -4.76 -0.39 5.36e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs6089829 1.000 rs6089828 chr20:61668998 C/T cg17470723 chr8:74884337 TCEB1 0.74 6.95 0.53 1.86e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9467773 0.649 rs2145318 chr6:26496603 T/A cg05738196 chr6:26577821 NA 0.73 8.21 0.59 2.39e-13 Intelligence (multi-trait analysis); TGCT cis rs11105298 0.786 rs3803128 chr12:89860319 C/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.02 -0.41 1.79e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs67311347 1.000 rs67680017 chr3:40533164 C/T cg13409248 chr3:40428643 ENTPD3 0.61 4.61 0.38 9.7e-6 Renal cell carcinoma; TGCT cis rs17712049 0.908 rs73694364 chr7:48200348 C/T cg16849860 chr7:48352531 ABCA13 0.32 5.26 0.43 6.19e-7 Refractive astigmatism; TGCT cis rs4325129 1.000 rs67371748 chr1:159489964 T/C cg20944283 chr1:159172620 CADM3 -0.29 -4.48 -0.37 1.65e-5 Obesity-related traits; TGCT cis rs28595532 0.920 rs56117870 chr4:119766583 T/C cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs72615157 0.561 rs113401658 chr7:99858505 C/T cg00814883 chr7:100076585 TSC22D4 -0.59 -5.7 -0.46 8.45e-8 Lung function (FEV1/FVC); TGCT cis rs6669919 0.967 rs6678844 chr1:211674774 G/T cg26515805 chr1:211431828 RCOR3 -0.39 -4.51 -0.38 1.5e-5 Intelligence (multi-trait analysis); TGCT cis rs17473412 0.804 rs9327295 chr5:122742602 G/T cg15125798 chr5:122621645 NA 0.57 5.04 0.41 1.64e-6 Total body bone mineral density; TGCT cis rs3784262 0.740 rs33960206 chr15:58288731 C/G cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.95 -0.47 2.58e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs3091242 0.967 rs1053438 chr1:25687901 T/C cg10117171 chr1:25599238 RHD 0.35 5.73 0.46 7.31e-8 Erythrocyte sedimentation rate; TGCT cis rs3796352 1.000 rs2336540 chr3:52974589 G/A cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs13191362 0.938 rs35760705 chr6:163020637 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.91 0.4 2.85e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4886920 0.601 rs12901558 chr15:78076379 G/A cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs112217694 1.000 rs7665931 chr4:104660682 C/T cg24090629 chr4:104641072 TACR3 -0.88 -4.79 -0.39 4.73e-6 Menarche (age at onset); TGCT cis rs6540559 0.546 rs735693 chr1:210033988 A/C cg21951975 chr1:209979733 IRF6 0.76 5.93 0.47 2.83e-8 Cleft lip with or without cleft palate; TGCT cis rs2033711 0.902 rs4801589 chr19:58953398 C/G cg12042659 chr19:58951599 ZNF132 0.51 4.54 0.38 1.29e-5 Uric acid clearance; TGCT cis rs7017914 0.875 rs3098871 chr8:71930415 C/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.56 -5.11 -0.42 1.19e-6 Bone mineral density; TGCT cis rs832540 0.669 rs173764 chr5:56198920 C/T cg24531977 chr5:56204891 C5orf35 -0.64 -6.36 -0.5 3.51e-9 Coronary artery disease; TGCT cis rs9467773 0.836 rs1977198 chr6:26466225 A/C cg09904177 chr6:26538194 HMGN4 0.55 4.94 0.41 2.46e-6 Intelligence (multi-trait analysis); TGCT cis rs17253792 0.571 rs112129578 chr14:56028415 T/C cg01858014 chr14:56050164 KTN1 -0.36 -4.54 -0.38 1.33e-5 Putamen volume; TGCT cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6964587 1.000 rs12539231 chr7:91634963 G/A cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs7618915 0.501 rs34157897 chr3:52716937 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.6 0.51 1.05e-9 Bipolar disorder; TGCT cis rs1580019 0.563 rs13225132 chr7:32800975 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.13 13.5 0.77 4.23e-26 Cognitive ability; TGCT cis rs2243480 1.000 rs160644 chr7:65558186 C/T cg20637647 chr7:64974828 NA 0.88 5.34 0.43 4.19e-7 Diabetic kidney disease; TGCT cis rs1008375 1.000 rs11737138 chr4:17657986 G/A cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2469997 1.000 rs2470006 chr8:120358591 G/C cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs936229 0.861 rs11634474 chr15:75116184 C/G cg10253484 chr15:75165896 SCAMP2 -0.66 -5.34 -0.43 4.28e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs4242434 0.819 rs7826059 chr8:22512068 T/C cg03733263 chr8:22462867 KIAA1967 -1.1 -15.66 -0.81 3.7e-31 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9926296 0.656 rs4522419 chr16:89853307 T/C cg27121462 chr16:89883253 FANCA 0.6 5.66 0.45 1.02e-7 Vitiligo; TGCT cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs778371 0.788 rs4973569 chr2:233767037 A/G cg08000102 chr2:233561755 GIGYF2 -0.55 -5.46 -0.44 2.53e-7 Schizophrenia; TGCT cis rs514406 0.792 rs1242201 chr1:53344748 G/A cg25767906 chr1:53392781 SCP2 -0.57 -6.88 -0.53 2.61e-10 Monocyte count; TGCT cis rs9486715 0.867 rs4438964 chr6:96917563 T/G cg18709589 chr6:96969512 KIAA0776 0.82 8.02 0.58 6.9e-13 Headache; TGCT trans rs1814175 0.817 rs4084376 chr11:49831160 T/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.14 -0.59 3.61e-13 Height; TGCT cis rs992157 0.661 rs10171839 chr2:219051314 C/T cg00012203 chr2:219082015 ARPC2 0.82 9.83 0.66 3.27e-17 Colorectal cancer; TGCT cis rs2019216 0.500 rs11651446 chr17:21967129 C/T cg22648282 chr17:21454238 C17orf51 -0.54 -4.49 -0.37 1.62e-5 Pelvic organ prolapse; TGCT cis rs801193 0.591 rs4506088 chr7:66135457 G/A cg11764359 chr7:65958608 NA -0.54 -4.85 -0.4 3.67e-6 Aortic root size; TGCT cis rs2115630 0.846 rs8024538 chr15:85368419 A/T cg11189052 chr15:85197271 WDR73 -0.59 -5.33 -0.43 4.54e-7 P wave terminal force; TGCT cis rs2072499 0.868 rs2758600 chr1:156195205 C/T cg24450063 chr1:156163899 SLC25A44 1.18 13.63 0.77 1.99e-26 Testicular germ cell tumor; TGCT cis rs3733585 0.699 rs7657340 chr4:9966772 A/T cg00071950 chr4:10020882 SLC2A9 -0.57 -6.85 -0.52 3.12e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs5750830 0.594 rs6001587 chr22:39819008 T/C cg02038168 chr22:39784481 NA -0.76 -6.36 -0.5 3.47e-9 Intelligence (multi-trait analysis); TGCT cis rs9640161 0.750 rs73170185 chr7:150030191 C/A cg10018233 chr7:150070692 REPIN1 0.32 4.62 0.38 9.41e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs9733 0.519 rs3768005 chr1:150680988 A/T cg09365446 chr1:150670422 GOLPH3L 0.3 4.59 0.38 1.05e-5 Tonsillectomy; TGCT cis rs7772486 0.743 rs1292339 chr6:145967086 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.78 -0.39 4.84e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg06238570 chr21:40685208 BRWD1 -0.82 -8.76 -0.62 1.19e-14 Cognitive function; TGCT cis rs12034598 1.000 rs11118166 chr1:207781995 A/G cg06640374 chr1:207250784 PFKFB2 0.3 4.48 0.37 1.69e-5 Inflammatory biomarkers; TGCT cis rs514406 0.861 rs505444 chr1:53251860 C/T cg08736216 chr1:53307985 ZYG11A -0.25 -4.86 -0.4 3.48e-6 Monocyte count; TGCT cis rs1511802 0.666 rs2292424 chr4:187120625 G/A cg19358738 chr4:186734530 SORBS2 0.17 4.44 0.37 1.95e-5 Blood protein levels; TGCT cis rs12971120 0.838 rs747176 chr18:72154931 G/A cg25817165 chr18:72167213 CNDP2 -0.3 -5.34 -0.43 4.26e-7 Refractive error; TGCT cis rs7772486 0.641 rs9390374 chr6:146368175 A/T cg05347473 chr6:146136440 FBXO30 0.58 5.56 0.45 1.57e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs17102423 0.623 rs2898862 chr14:65612144 G/A cg11161011 chr14:65562177 MAX -0.41 -5.54 -0.45 1.77e-7 Obesity-related traits; TGCT cis rs1055129 0.516 rs7218498 chr17:73931847 C/G cg10935138 chr17:73851978 WBP2 0.53 4.67 0.39 7.58e-6 White matter hyperintensity burden; TGCT cis rs4711350 0.954 rs11751943 chr6:33729718 G/C cg18005901 chr6:33739558 LEMD2 -0.57 -5.79 -0.46 5.31e-8 Schizophrenia; TGCT cis rs7246657 0.943 rs2112923 chr19:37940327 C/T cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs7213347 0.579 rs8072532 chr17:2045273 G/A cg22033759 chr17:1182267 TUSC5 -0.23 -4.65 -0.39 8.4e-6 Total body bone mineral density; TGCT cis rs1878931 0.520 rs2015640 chr16:3465018 G/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.73 -5.47 -0.44 2.36e-7 Body mass index (adult); TGCT cis rs10788575 0.805 rs12569998 chr10:89674157 A/C cg03166508 chr10:89453226 PAPSS2 0.31 4.71 0.39 6.55e-6 Type 2 diabetes; TGCT trans rs7613875 0.580 rs3774745 chr3:50204745 C/T cg21659725 chr3:3221576 CRBN -0.7 -7.99 -0.58 8.03e-13 Body mass index; TGCT trans rs66573146 0.803 rs60228659 chr4:7031704 G/A cg07817883 chr1:32538562 TMEM39B 1.66 8.05 0.59 5.84e-13 Granulocyte percentage of myeloid white cells; TGCT cis rs7772486 0.790 rs2249386 chr6:146186611 G/A cg13319975 chr6:146136371 FBXO30 -0.54 -4.81 -0.4 4.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg14851468 chr5:179071604 C5orf60 -0.23 -4.82 -0.4 4.17e-6 Lung cancer; TGCT cis rs9788682 0.894 rs4461039 chr15:78817447 A/T cg24631222 chr15:78858424 CHRNA5 -0.92 -8.06 -0.59 5.54e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs1799949 1.000 rs33945274 chr17:41280073 G/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs28386778 1.000 rs2665851 chr17:61957023 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.03 -0.41 1.65e-6 Prudent dietary pattern; TGCT cis rs10089 0.903 rs6862701 chr5:127391249 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg05665937 chr4:1216051 CTBP1 0.22 4.51 0.38 1.47e-5 Obesity-related traits; TGCT cis rs7647973 1.000 rs62259933 chr3:49469703 G/A cg07636037 chr3:49044803 WDR6 -0.7 -5.73 -0.46 7.08e-8 Menarche (age at onset); TGCT cis rs1865760 0.865 rs9393677 chr6:25945815 G/A cg17042849 chr6:26104293 HIST1H4C -0.52 -4.78 -0.39 4.97e-6 Height; TGCT cis rs4819052 1.000 rs9984901 chr21:46663952 C/T cg06618935 chr21:46677482 NA -0.36 -5.04 -0.41 1.59e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs3125734 0.582 rs7904465 chr10:64002393 G/A cg09941381 chr10:64027924 RTKN2 -0.37 -5.59 -0.45 1.41e-7 Rheumatoid arthritis; TGCT cis rs922182 0.967 rs34772505 chr15:64276772 C/T cg02919090 chr15:64263738 DAPK2 0.3 5.51 0.44 1.96e-7 Blood protein levels; TGCT cis rs4711336 1.000 rs4711336 chr6:33659046 A/G cg14003231 chr6:33640908 ITPR3 -0.31 -4.97 -0.41 2.2e-6 Height; TGCT cis rs916888 0.647 rs199524 chr17:44848438 G/T cg16520312 chr17:43971471 MAPT;LOC100128977 0.48 4.67 0.39 7.86e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2729354 0.903 rs2729371 chr11:57321322 A/G cg24343310 chr11:57249947 NA 0.3 4.96 0.41 2.28e-6 Blood protein levels; TGCT cis rs4901869 0.966 rs9972206 chr14:59336095 A/G cg02291164 chr14:59296302 NA 0.24 4.7 0.39 6.73e-6 Panic disorder; TGCT cis rs11676348 0.755 rs62183956 chr2:219046122 C/T cg00012203 chr2:219082015 ARPC2 0.6 5.73 0.46 7.33e-8 Ulcerative colitis; TGCT cis rs4851254 0.961 rs13011181 chr2:100732446 T/C cg07810366 chr2:100720526 AFF3 -0.42 -4.79 -0.4 4.68e-6 Intelligence (multi-trait analysis); TGCT cis rs138229 0.506 rs138233 chr22:50559953 G/A cg16473166 chr22:50639996 SELO 0.58 4.76 0.39 5.34e-6 Behavioural disinhibition (generation interaction); TGCT cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs17376456 0.825 rs10075217 chr5:93176774 C/G cg25358565 chr5:93447407 FAM172A 0.99 7.46 0.56 1.29e-11 Diabetic retinopathy; TGCT cis rs2840044 0.963 rs225247 chr17:33944590 T/A cg05299278 chr17:33885742 SLFN14 0.23 5.07 0.41 1.38e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs7940866 0.903 rs10791109 chr11:130850377 A/C cg05962950 chr11:130786565 SNX19 0.64 6.37 0.5 3.32e-9 Schizophrenia; TGCT cis rs3809566 0.632 rs9806533 chr15:63328298 A/G cg00520135 chr15:63333846 TPM1 -0.4 -4.9 -0.4 2.95e-6 Platelet count; TGCT cis rs4820539 1.000 rs4822358 chr22:23474795 A/G cg14186256 chr22:23484241 RTDR1 0.99 12.54 0.75 8.46e-24 Bone mineral density; TGCT cis rs17473412 0.804 rs6595441 chr5:122724446 A/G cg15125798 chr5:122621645 NA -0.57 -5.15 -0.42 9.93e-7 Total body bone mineral density; TGCT cis rs7829975 0.582 rs6982832 chr8:8792217 A/C cg00184457 chr8:8946301 NA -0.23 -4.44 -0.37 2e-5 Mood instability; TGCT cis rs367615 0.959 rs17161951 chr5:108930590 A/G cg17395555 chr5:108820864 NA -0.28 -4.49 -0.37 1.59e-5 Colorectal cancer (SNP x SNP interaction); TGCT cis rs36051895 0.632 rs12343038 chr9:5178579 A/G cg02405213 chr9:5042618 JAK2 0.74 10.54 0.69 6.32e-19 Pediatric autoimmune diseases; TGCT cis rs492146 0.765 rs670960 chr6:52843796 A/G cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs9660992 0.573 rs7368327 chr1:205214792 C/T cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs9814567 1.000 rs2370641 chr3:134222161 A/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9926296 0.744 rs154657 chr16:89708096 A/G cg04287289 chr16:89883240 FANCA 0.5 4.79 0.39 4.73e-6 Vitiligo; TGCT cis rs4654899 0.758 rs6426667 chr1:21396216 C/A cg01072550 chr1:21505969 NA -0.56 -9.08 -0.63 2.14e-15 Superior frontal gyrus grey matter volume; TGCT cis rs6912958 0.559 rs242270 chr6:88062190 C/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.41 -5.31 -0.43 4.94e-7 Monocyte percentage of white cells; TGCT cis rs7809950 0.723 rs2237662 chr7:106874065 C/G cg23024343 chr7:107201750 COG5 -0.41 -5.62 -0.45 1.17e-7 Coronary artery disease; TGCT trans rs1814175 0.647 rs2903409 chr11:49953612 C/G cg15704280 chr7:45808275 SEPT13 -0.63 -7.35 -0.55 2.28e-11 Height; TGCT cis rs4689388 0.926 rs5018648 chr4:6292818 C/G cg25554036 chr4:6271136 WFS1 -0.54 -7.56 -0.56 7.66e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs8177253 0.763 rs8177224 chr3:133474003 C/G cg11941060 chr3:133502564 NA 0.25 5.24 0.43 6.58e-7 Iron status biomarkers; TGCT cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg02353165 chr6:42928485 GNMT 0.95 9.72 0.66 5.91e-17 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs8017423 0.967 rs7155315 chr14:90700787 G/A cg04374321 chr14:90722782 PSMC1 0.77 8.05 0.59 5.68e-13 Mortality in heart failure; TGCT cis rs12220238 1.000 rs10824103 chr10:75949415 A/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs769267 0.965 rs2965191 chr19:19453521 T/G cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs2760061 0.603 rs697762 chr1:228192410 G/A cg02753203 chr1:228287806 NA 0.33 6.31 0.49 4.41e-9 Diastolic blood pressure; TGCT cis rs7523273 0.565 rs2796250 chr1:207903654 T/C cg22525895 chr1:207977042 MIR29B2 -0.33 -5.33 -0.43 4.38e-7 Schizophrenia; TGCT cis rs367615 0.704 rs60538082 chr5:108829101 A/G cg17395555 chr5:108820864 NA 0.31 5.92 0.47 2.9e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2842992 0.915 rs1322427 chr6:160075454 C/A cg11366901 chr6:160182831 ACAT2 1.02 6.67 0.51 7.59e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs9372498 0.908 rs72967581 chr6:118699329 G/A cg18833306 chr6:118973337 C6orf204 -0.61 -4.81 -0.4 4.28e-6 Diastolic blood pressure; TGCT cis rs587847 0.737 rs1520958 chr15:37658456 C/G cg00216138 chr15:37171175 LOC145845 -0.31 -4.45 -0.37 1.91e-5 Intraocular pressure; TGCT cis rs10992471 0.729 rs13284038 chr9:95555488 A/G cg13798575 chr9:95087839 CENPP;NOL8 -0.58 -5.32 -0.43 4.62e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs2153535 0.580 rs9393021 chr6:8466123 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9926296 0.656 rs7191144 chr16:89823393 C/T cg26513180 chr16:89883248 FANCA 0.7 6.76 0.52 4.86e-10 Vitiligo; TGCT cis rs13188771 0.775 rs67015325 chr5:100870217 C/T cg18665594 chr5:101119420 NA 0.47 4.57 0.38 1.14e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs9467711 0.790 rs17598658 chr6:26175866 A/C cg16898833 chr6:26189333 HIST1H4D 1.44 6.24 0.49 6.22e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs4654899 1.000 rs6681064 chr1:21339644 A/G cg01072550 chr1:21505969 NA -0.5 -7.97 -0.58 8.84e-13 Superior frontal gyrus grey matter volume; TGCT cis rs854765 0.624 rs7359509 chr17:17741875 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.67 -0.51 7.5e-10 Total body bone mineral density; TGCT cis rs853679 0.517 rs9348797 chr6:28137533 G/C cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs75686122 0.892 rs1895900 chr8:104602709 C/T cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT cis rs9393777 0.513 rs7754159 chr6:26620312 G/A cg15659132 chr6:26577336 NA -0.72 -5.29 -0.43 5.24e-7 Intelligence (multi-trait analysis); TGCT cis rs1857353 0.908 rs3845362 chr1:75885158 A/G cg11838876 chr1:75668600 SLC44A5 -0.46 -4.5 -0.37 1.54e-5 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs2370759 1.000 rs2769241 chr10:32556229 T/C cg01819863 chr10:32635814 EPC1 -1.01 -9.82 -0.66 3.44e-17 Sexual dysfunction (female); TGCT cis rs12971120 0.891 rs2303463 chr18:72168608 G/A cg26446133 chr18:72167187 CNDP2 -0.36 -6.11 -0.48 1.2e-8 Refractive error; TGCT cis rs28386778 0.897 rs2156903 chr17:61937179 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs78487399 0.808 rs72865267 chr2:43726328 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.49 0.37 1.59e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9926296 0.585 rs8058009 chr16:89856439 G/A cg26513180 chr16:89883248 FANCA 0.85 8.19 0.59 2.75e-13 Vitiligo; TGCT cis rs1577917 0.917 rs2218594 chr6:86543766 A/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.47 -0.44 2.33e-7 Response to antipsychotic treatment; TGCT cis rs1395 0.710 rs2083363 chr2:27475318 G/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 7.72 0.57 3.38e-12 Blood metabolite levels; TGCT cis rs12530845 0.524 rs7795267 chr7:135308455 C/G cg23117316 chr7:135346802 PL-5283 -0.51 -4.52 -0.38 1.4e-5 Red blood cell traits; TGCT cis rs589448 0.934 rs554591 chr12:69753847 T/C cg14784868 chr12:69753453 YEATS4 0.9 10.55 0.69 5.67e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs3008870 1.000 rs1925408 chr1:67365034 C/T cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.84 0.73 4.25e-22 Lymphocyte percentage of white cells; TGCT cis rs13326165 0.760 rs498946 chr3:52434967 T/C cg27565382 chr3:53032988 SFMBT1 0.37 5.1 0.42 1.26e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs1903068 1.000 rs73236109 chr4:56007425 C/T cg01777861 chr4:56023843 NA 0.56 6.55 0.51 1.39e-9 Endometriosis; TGCT cis rs4927850 1.000 rs7627868 chr3:195753473 A/T cg22891161 chr3:195456627 MUC20 -0.23 -5.38 -0.44 3.53e-7 Pancreatic cancer; TGCT cis rs7552404 0.961 rs448710 chr1:76116554 T/C cg22875332 chr1:76189707 ACADM -0.8 -9.79 -0.66 4.2e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2072499 0.931 rs1052053 chr1:156202173 A/G cg25208724 chr1:156163844 SLC25A44 0.96 12.24 0.74 4.45e-23 Testicular germ cell tumor; TGCT cis rs11825685 1.000 rs11825685 chr11:134573810 C/T cg26418160 chr11:134306122 NA 0.39 5.15 0.42 9.83e-7 IgG glycosylation; TGCT cis rs13242816 1.000 rs35595472 chr7:116122306 G/A cg02799643 chr7:116139180 CAV2 -0.49 -5.53 -0.45 1.78e-7 P wave duration; TGCT cis rs707040 1.000 rs7566536 chr2:155237893 C/T cg18104148 chr2:154337490 NA 0.19 4.56 0.38 1.2e-5 Sudden cardiac arrest; TGCT cis rs6964587 1.000 rs11982213 chr7:91722966 A/G cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs3818285 0.679 rs2475275 chr10:111633979 C/T cg00817464 chr10:111662876 XPNPEP1 0.32 5.57 0.45 1.51e-7 Superior crus of antihelix expression; TGCT cis rs6840360 0.571 rs17275598 chr4:152568478 C/A cg17479576 chr4:152424074 FAM160A1 -0.73 -7.95 -0.58 9.69e-13 Intelligence (multi-trait analysis); TGCT cis rs7017914 0.875 rs2639897 chr8:71920676 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs7666738 0.830 rs28769113 chr4:98950371 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9467711 0.516 rs1165168 chr6:25859508 A/C cg12310025 chr6:25882481 NA -0.72 -4.77 -0.39 5.17e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1505368 0.781 rs4673664 chr2:213277649 T/C cg16329650 chr2:213403929 ERBB4 0.64 6.44 0.5 2.41e-9 Symmetrical dimethylarginine levels; TGCT cis rs2153535 0.601 rs2327054 chr6:8443130 T/C cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs13191362 0.507 rs2849534 chr6:163144657 T/A cg21926612 chr6:163149169 PACRG;PARK2 -0.59 -5.28 -0.43 5.5e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs514406 0.861 rs1412706 chr1:53237721 G/A cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT trans rs2469997 1.000 rs2447167 chr8:120366068 T/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs7772486 0.790 rs2253307 chr6:146196181 T/G cg23711669 chr6:146136114 FBXO30 0.95 10.8 0.7 1.44e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs7226408 0.857 rs72890579 chr18:34626456 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs1008375 1.000 rs56308330 chr4:17643050 G/A cg18681998 chr4:17616180 MED28 1.0 11.88 0.73 3.32e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2204008 0.805 rs7296063 chr12:37964775 T/G cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs886126 1.000 rs4766451 chr12:111670682 G/T cg10833066 chr12:111807467 FAM109A 0.32 5.56 0.45 1.59e-7 Coronary heart disease; TGCT cis rs1799949 1.000 rs12944458 chr17:41180772 C/T cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs2243480 1.000 rs34560516 chr7:65404092 A/T cg18252515 chr7:66147081 NA -1.15 -7.05 -0.53 1.1e-10 Diabetic kidney disease; TGCT cis rs17711722 0.510 rs73142128 chr7:65331109 A/C cg20849893 chr7:64541193 NA 0.49 5.1 0.42 1.24e-6 Calcium levels; TGCT cis rs4499344 0.921 rs12973855 chr19:33085395 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.7 -6.32 -0.49 4.21e-9 Mean platelet volume; TGCT cis rs4665809 0.549 rs62130460 chr2:26472718 T/C cg04944784 chr2:26401820 FAM59B 0.77 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs7267979 0.932 rs6115214 chr20:25557426 C/T cg16686733 chr20:25566563 NINL -0.55 -5.57 -0.45 1.53e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3008870 1.000 rs2065001 chr1:67486509 C/G cg08660285 chr1:67390436 MIER1;WDR78 1.05 10.47 0.68 9.28e-19 Lymphocyte percentage of white cells; TGCT trans rs7726839 0.561 rs72703044 chr5:579737 G/A cg25482853 chr8:67687455 SGK3 1.05 9.29 0.64 6.67e-16 Obesity-related traits; TGCT cis rs6460942 0.915 rs2216051 chr7:12304054 G/A cg06484146 chr7:12443880 VWDE -0.49 -5.17 -0.42 9.27e-7 Coronary artery disease; TGCT cis rs9952991 0.528 rs612058 chr18:12850211 T/C cg23598886 chr18:12777645 NA 0.57 5.05 0.41 1.51e-6 Inflammatory skin disease; TGCT cis rs2243480 1.000 rs437889 chr7:65509234 G/A cg20637647 chr7:64974828 NA 1.0 5.59 0.45 1.4e-7 Diabetic kidney disease; TGCT cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg17554472 chr22:41940697 POLR3H -0.46 -4.69 -0.39 7.09e-6 Vitiligo; TGCT cis rs10256972 0.732 rs1574108 chr7:1105805 T/C cg03188948 chr7:1209495 NA 0.42 5.53 0.44 1.84e-7 Longevity;Endometriosis; TGCT cis rs7542091 0.704 rs1108628 chr1:210041150 A/G cg22029157 chr1:209979665 IRF6 0.65 6.3 0.49 4.63e-9 Monobrow; TGCT cis rs12579753 0.872 rs34415838 chr12:82122078 T/C cg21231944 chr12:82153410 PPFIA2 -0.34 -4.55 -0.38 1.28e-5 Resting heart rate; TGCT cis rs9611565 0.559 rs132761 chr22:42004371 C/T cg03806693 chr22:41940476 POLR3H 1.07 11.4 0.72 4.95e-21 Vitiligo; TGCT cis rs12142240 0.698 rs1057534 chr1:46815880 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1023500 0.596 rs133369 chr22:42463814 C/T cg05082376 chr22:42548792 NA -0.23 -5.44 -0.44 2.72e-7 Schizophrenia; TGCT cis rs7772486 0.754 rs9386134 chr6:146145508 G/A cg05347473 chr6:146136440 FBXO30 0.52 4.94 0.41 2.5e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs7618501 0.633 rs9853222 chr3:50022926 T/C cg21659725 chr3:3221576 CRBN 0.76 9.35 0.64 4.85e-16 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.659 rs9873072 chr3:44516496 G/A cg25151919 chr3:44754333 ZNF502 -0.39 -4.58 -0.38 1.12e-5 Depressive symptoms; TGCT cis rs6495367 1.000 rs3851677 chr15:79380869 C/T cg17916960 chr15:79447300 NA 0.36 5.2 0.42 8.06e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs9911578 0.835 rs1476596 chr17:56485358 C/T cg05425664 chr17:57184151 TRIM37 -0.61 -5.74 -0.46 6.98e-8 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.791 rs10033994 chr4:98969582 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2549003 0.674 rs960757 chr5:131826310 G/A cg21138405 chr5:131827807 IRF1 0.18 4.53 0.38 1.37e-5 Asthma (sex interaction); TGCT trans rs10802346 0.545 rs6662672 chr1:246387611 A/C cg22732515 chr19:44031385 ETHE1 0.83 6.62 0.51 9.79e-10 Fractional exhaled nitric oxide (childhood); TGCT cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg10047753 chr17:41438598 NA 0.97 9.76 0.66 4.73e-17 Menopause (age at onset); TGCT cis rs6088590 0.965 rs910869 chr20:33292777 C/T cg24642439 chr20:33292090 TP53INP2 0.7 6.41 0.5 2.75e-9 Coronary artery disease; TGCT cis rs4665809 0.887 rs28699126 chr2:26357294 C/T cg25036284 chr2:26402008 FAM59B -0.53 -4.53 -0.38 1.37e-5 Gut microbiome composition (summer); TGCT cis rs6921919 0.583 rs6928771 chr6:28375209 T/G cg18815343 chr6:28367644 ZSCAN12 -0.53 -5.13 -0.42 1.09e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6435862 0.593 rs34732883 chr2:215674371 C/T cg04004882 chr2:215674386 BARD1 -0.77 -6.88 -0.53 2.66e-10 Neuroblastoma (high-risk); TGCT cis rs6674176 0.611 rs3120803 chr1:44386615 A/G cg12908607 chr1:44402522 ARTN -0.73 -4.61 -0.38 9.87e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2832191 0.791 rs2832199 chr21:30498501 G/A cg24692254 chr21:30365293 RNF160 -0.89 -9.49 -0.65 2.2e-16 Dental caries; TGCT cis rs1949733 0.701 rs4696828 chr4:8455604 G/A cg11789530 chr4:8429930 ACOX3 -0.54 -5.13 -0.42 1.08e-6 Response to antineoplastic agents; TGCT cis rs514406 0.861 rs7524476 chr1:53240212 C/T cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs2243480 1.000 rs57057549 chr7:65405738 A/G cg18252515 chr7:66147081 NA -1.19 -7.51 -0.56 1.02e-11 Diabetic kidney disease; TGCT cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs56011263 0.687 rs11734460 chr4:705074 C/T cg17689763 chr4:710664 PCGF3 -0.24 -7.23 -0.54 4.25e-11 White blood cell count; TGCT cis rs7772486 0.875 rs2180192 chr6:146322284 T/C cg23711669 chr6:146136114 FBXO30 0.88 9.65 0.65 9.01e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs8031584 0.678 rs35098644 chr15:31145440 A/G cg08109568 chr15:31115862 NA -0.38 -4.83 -0.4 3.99e-6 Huntington's disease progression; TGCT cis rs317865 0.737 rs73234644 chr4:16190661 T/G cg04764131 chr4:16228633 TAPT1;FLJ39653 0.78 5.11 0.42 1.18e-6 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs11690935 0.788 rs10201053 chr2:172889558 A/G cg13550731 chr2:172543902 DYNC1I2 -1.03 -10.05 -0.67 9.72e-18 Schizophrenia; TGCT cis rs778371 0.723 rs12105766 chr2:233617647 A/G cg08000102 chr2:233561755 GIGYF2 0.72 8.42 0.6 7.71e-14 Schizophrenia; TGCT cis rs10408945 1 rs10408945 chr19:16576991 G/T cg14704714 chr19:15740395 CYP4F8 -0.41 -4.49 -0.37 1.6e-5 Lymphocyte counts; TGCT cis rs10876993 0.890 rs1678539 chr12:58060359 A/G cg15848620 chr12:58087721 OS9 -0.74 -5.98 -0.47 2.23e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs765787 0.530 rs28733848 chr15:45516047 C/T cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT cis rs62244186 0.608 rs2888390 chr3:44511405 G/A cg02073558 chr3:44770973 ZNF501 0.61 5.79 0.46 5.39e-8 Depressive symptoms; TGCT cis rs7666738 0.716 rs11721453 chr4:99045485 G/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT trans rs4919669 0.668 rs4919666 chr10:104384029 G/A cg24066601 chr6:26271455 HIST1H3G 0.66 6.81 0.52 3.7e-10 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs7772486 0.686 rs1292336 chr6:145967818 T/C cg05347473 chr6:146136440 FBXO30 -0.47 -4.49 -0.37 1.58e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs4631830 0.863 rs2843546 chr10:51518688 A/C cg10326726 chr10:51549505 MSMB -0.26 -5.37 -0.43 3.68e-7 Prostate-specific antigen levels; TGCT cis rs2721195 0.577 rs4532636 chr8:145904423 A/C cg15857475 chr8:145742913 RECQL4;LRRC14 -0.95 -9.71 -0.66 6.5e-17 Age at first birth; TGCT cis rs2836974 0.897 rs2836933 chr21:40564202 C/G cg17971929 chr21:40555470 PSMG1 0.98 9.67 0.66 8.18e-17 Cognitive function; TGCT cis rs2439831 0.867 rs2920781 chr15:43924682 G/A cg02155558 chr15:43621948 ADAL;LCMT2 0.88 6.61 0.51 1.03e-9 Lung cancer in ever smokers; TGCT cis rs11650494 0.831 rs11650886 chr17:47449193 G/A cg08112188 chr17:47440006 ZNF652 1.04 5.31 0.43 4.85e-7 Prostate cancer; TGCT cis rs12497850 0.931 rs6446205 chr3:49035211 C/T cg06212747 chr3:49208901 KLHDC8B 0.61 5.49 0.44 2.2e-7 Parkinson's disease; TGCT cis rs4689388 0.890 rs4342257 chr4:6290037 G/C cg14416269 chr4:6271139 WFS1 0.37 4.88 0.4 3.15e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT trans rs629535 0.590 rs62513426 chr8:70136843 T/G cg21567404 chr3:27674614 NA -0.52 -7.76 -0.57 2.74e-12 Dupuytren's disease; TGCT cis rs9302065 0.565 rs2993586 chr13:95962578 T/C cg24476569 chr13:95954382 ABCC4 -0.54 -8.26 -0.6 1.9e-13 Blood metabolite levels; TGCT cis rs6882076 0.925 rs4704826 chr5:156392082 C/A cg12943317 chr5:156479607 HAVCR1 -0.29 -5.6 -0.45 1.3e-7 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT trans rs1814175 0.781 rs12286395 chr11:49954062 C/G cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT trans rs3780486 0.505 rs959749 chr9:33147858 T/C cg20290983 chr6:43655470 MRPS18A 0.77 8.33 0.6 1.28e-13 IgG glycosylation; TGCT trans rs2243480 0.522 rs1638736 chr7:66092308 A/T cg07424592 chr7:64974309 NA 1.36 8.8 0.62 1.01e-14 Diabetic kidney disease; TGCT cis rs10771431 1.000 rs10771431 chr12:9380859 C/T cg08997352 chr12:9597637 DDX12 -0.26 -5.65 -0.45 1.04e-7 Breast size; TGCT cis rs875971 1.000 rs1144894 chr7:65542894 A/G cg18876405 chr7:65276391 NA -0.35 -5.19 -0.42 8.26e-7 Aortic root size; TGCT cis rs1467026 0.584 rs11712581 chr3:12807781 T/C cg05775895 chr3:12838266 CAND2 0.72 7.41 0.55 1.73e-11 P wave duration; TGCT cis rs56235845 0.694 rs11749830 chr5:176766547 G/A cg16006841 chr5:176797999 RGS14 0.52 7.69 0.57 3.9e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs7833790 0.700 rs7834483 chr8:82704828 A/G cg17211192 chr8:82754475 SNX16 -0.89 -7.91 -0.58 1.24e-12 Diastolic blood pressure; TGCT cis rs10197940 0.662 rs13555 chr2:152333304 C/A cg06191203 chr2:152266755 RIF1 -0.71 -6.28 -0.49 5.14e-9 Lung cancer; TGCT cis rs4665809 1.000 rs1550382 chr2:26266877 T/G cg25036284 chr2:26402008 FAM59B -0.56 -4.85 -0.4 3.62e-6 Gut microbiome composition (summer); TGCT cis rs6952808 0.630 rs10239050 chr7:2158390 A/G cg22963979 chr7:1858916 MAD1L1 -0.44 -6.99 -0.53 1.5e-10 Bipolar disorder and schizophrenia; TGCT cis rs72781680 0.821 rs72790329 chr2:24129277 A/G cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs270601 0.721 rs162894 chr5:131611872 T/G cg12564285 chr5:131593104 PDLIM4 0.41 4.74 0.39 5.82e-6 Acylcarnitine levels; TGCT trans rs2727020 0.595 rs10839286 chr11:49497063 C/A cg15704280 chr7:45808275 SEPT13 -0.74 -8.49 -0.61 5.28e-14 Coronary artery disease; TGCT cis rs6867032 1.000 rs16902321 chr5:2015148 A/G cg26168224 chr5:2018326 NA 0.43 7.86 0.58 1.62e-12 Gut microbiome composition (winter); TGCT cis rs11122272 0.735 rs2790885 chr1:231529925 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.34 -0.49 3.83e-9 Hemoglobin concentration; TGCT cis rs7904368 0.806 rs3858182 chr10:16855094 C/T cg14835575 chr10:16859367 RSU1 0.7 7.48 0.56 1.19e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs34172651 0.517 rs3803716 chr16:24802325 C/T cg06028605 chr16:24865363 SLC5A11 0.41 4.57 0.38 1.17e-5 Intelligence (multi-trait analysis); TGCT cis rs7226408 0.857 rs72890583 chr18:34627906 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs116103936 chr4:98954531 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.897 rs1006723 chr4:17618524 G/A cg18681998 chr4:17616180 MED28 1.06 11.58 0.72 1.76e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT trans rs57221529 0.766 rs12521988 chr5:556421 C/T cg11887960 chr12:57824829 NA 1.15 9.35 0.64 4.71e-16 Lung disease severity in cystic fibrosis; TGCT cis rs3125734 0.633 rs4979782 chr10:63998527 C/T cg09941381 chr10:64027924 RTKN2 -0.37 -5.58 -0.45 1.45e-7 Rheumatoid arthritis; TGCT cis rs17376456 0.877 rs10040648 chr5:93490301 G/C cg21475434 chr5:93447410 FAM172A 0.63 4.6 0.38 1.01e-5 Diabetic retinopathy; TGCT cis rs854765 0.583 rs9904163 chr17:17830553 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.74 7.73 0.57 3.18e-12 Total body bone mineral density; TGCT cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6121246 0.954 rs6060992 chr20:30431255 G/T cg13852791 chr20:30311386 BCL2L1 0.76 5.67 0.45 9.7e-8 Mean corpuscular hemoglobin; TGCT cis rs11098499 0.865 rs9996417 chr4:120295862 T/C cg09307838 chr4:120376055 NA 0.66 6.46 0.5 2.15e-9 Corneal astigmatism; TGCT cis rs8062405 0.824 rs7191618 chr16:28565667 C/G cg09754948 chr16:28834200 ATXN2L 0.63 4.97 0.41 2.16e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs709400 1.000 rs61995780 chr14:104120612 A/G cg26031613 chr14:104095156 KLC1 1.14 17.16 0.84 1.53e-34 Body mass index; TGCT cis rs4660261 0.526 rs2906458 chr1:44336389 A/G cg13606994 chr1:44402422 ARTN 0.41 4.46 0.37 1.82e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs58382845 chr8:58169851 A/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9906944 0.742 rs4073893 chr17:47118523 A/G cg07075026 chr17:47091521 IGF2BP1 -0.43 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg02458000 chr6:26745757 NA 0.65 6.34 0.49 3.92e-9 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.830 rs10085549 chr7:99983135 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.97 -8.51 -0.61 4.86e-14 Platelet count; TGCT cis rs71636778 0.509 rs60340200 chr1:27287716 A/G cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs4383453 0.539 rs56384012 chr3:123098176 G/A cg04890266 chr3:123102914 ADCY5 -0.5 -8.3 -0.6 1.48e-13 Gestational age at birth (maternal effect); TGCT cis rs6582630 0.555 rs7965311 chr12:38513307 G/A cg26384229 chr12:38710491 ALG10B -0.8 -7.43 -0.56 1.51e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs9814567 1.000 rs11927068 chr3:134266321 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6882046 0.513 rs34318 chr5:88027149 G/A cg22951263 chr5:87985283 NA -0.54 -5.8 -0.46 5.2100000000000003e-08 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs2836974 1.000 rs28360661 chr21:40681972 G/C cg06238570 chr21:40685208 BRWD1 0.6 5.25 0.43 6.39e-7 Cognitive function; TGCT cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs9486715 0.867 rs2475025 chr6:96988696 A/T cg18709589 chr6:96969512 KIAA0776 -0.79 -7.84 -0.58 1.79e-12 Headache; TGCT cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg01448562 chr3:133502909 NA -0.26 -4.9 -0.4 2.97e-6 Iron status biomarkers; TGCT cis rs7647973 0.626 rs1491985 chr3:49739507 G/C cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs72781680 0.752 rs72796114 chr2:23906133 C/G cg08917208 chr2:24149416 ATAD2B 1.0 5.56 0.45 1.59e-7 Lymphocyte counts; TGCT cis rs208520 0.909 rs60604603 chr6:67022955 T/C cg07460842 chr6:66804631 NA 0.69 5.72 0.46 7.53e-8 Exhaled nitric oxide output; TGCT cis rs6684514 1.000 rs2241106 chr1:156218910 C/G cg16558208 chr1:156270281 VHLL 0.46 8.4 0.6 8.73e-14 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6582630 0.598 rs10880645 chr12:38556172 G/A cg26384229 chr12:38710491 ALG10B -0.53 -4.77 -0.39 5.12e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9291683 0.530 rs11723591 chr4:9985398 T/A cg11266682 chr4:10021025 SLC2A9 0.62 8.49 0.61 5.26e-14 Bone mineral density; TGCT cis rs492146 0.765 rs316132 chr6:52847966 C/T cg06706454 chr6:52930286 FBXO9 -0.53 -4.95 -0.41 2.37e-6 Epilepsy (remission after treatment); TGCT cis rs4720575 1.000 rs6463383 chr7:47091686 A/G cg00036614 chr7:47093842 NA 0.2 5.11 0.42 1.18e-6 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs11098499 0.618 rs6858383 chr4:120296772 T/C cg09307838 chr4:120376055 NA 0.66 6.48 0.5 1.98e-9 Corneal astigmatism; TGCT cis rs4665809 0.590 rs35615763 chr2:26468778 C/G cg04944784 chr2:26401820 FAM59B 0.76 6.24 0.49 6.46e-9 Gut microbiome composition (summer); TGCT cis rs7681440 0.669 rs6814481 chr4:90805660 C/T cg10208370 chr4:90758469 SNCA -0.57 -5.33 -0.43 4.48e-7 Dementia with Lewy bodies; TGCT cis rs12134133 1.000 rs6660254 chr1:207446091 C/G cg02152968 chr1:207494213 CD55 0.6 4.53 0.38 1.36e-5 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs9291683 0.546 rs13110307 chr4:10044364 T/C cg11266682 chr4:10021025 SLC2A9 0.6 7.52 0.56 9.49e-12 Bone mineral density; TGCT cis rs7224685 0.569 rs8082483 chr17:4000849 G/A cg09580393 chr17:4869866 SPAG7 -0.38 -4.48 -0.37 1.64e-5 Type 2 diabetes; TGCT cis rs1552244 0.626 rs2886396 chr3:10037670 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs6545883 0.931 rs12713438 chr2:61725501 G/A cg15711740 chr2:61764176 XPO1 -0.5 -4.51 -0.38 1.46e-5 Tuberculosis; TGCT cis rs13191362 1.000 rs13195226 chr6:163006421 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs511515 1 rs511515 chr6:33541507 A/G cg07679836 chr6:33548423 BAK1 0.42 5.86 0.47 3.91e-8 Eosinophil counts;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs6032067 0.571 rs6017536 chr20:43907369 G/T cg16667508 chr20:43936853 MATN4;RBPJL -0.48 -7.23 -0.54 4.28e-11 Blood protein levels; TGCT cis rs319204 0.843 rs178549 chr5:146295990 A/G cg25021259 chr5:146258546 PPP2R2B -0.36 -4.54 -0.38 1.29e-5 Schizophrenia; TGCT cis rs7208859 0.524 rs8065744 chr17:29099449 C/T cg13385521 chr17:29058706 SUZ12P 0.82 4.86 0.4 3.52e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7666738 0.822 rs17484018 chr4:98988960 G/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs72615157 0.628 rs7801070 chr7:99847147 T/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.61 4.72 0.39 6.31e-6 Lung function (FEV1/FVC); TGCT cis rs9787249 0.957 rs11809515 chr1:40205326 C/A cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs62380364 0.557 rs663046 chr5:88036486 C/T cg22951263 chr5:87985283 NA -0.55 -5.96 -0.47 2.46e-8 Intelligence (multi-trait analysis); TGCT cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg13877915 chr19:58951672 ZNF132 0.9 10.8 0.7 1.44e-19 Uric acid clearance; TGCT cis rs9611565 0.649 rs139540 chr22:42178040 C/T cg13695892 chr22:41940480 POLR3H -0.85 -8.02 -0.58 6.79e-13 Vitiligo; TGCT cis rs1008375 1.000 rs28693609 chr4:17645233 C/T cg10189774 chr4:17578691 LAP3 0.58 5.26 0.43 6.24e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2075371 0.611 rs12707154 chr7:134015832 C/T cg11752832 chr7:134001865 SLC35B4 0.63 5.07 0.41 1.41e-6 Mean platelet volume; TGCT cis rs7172809 0.599 rs17472200 chr15:77783812 C/G cg22256960 chr15:77711686 NA -0.51 -4.86 -0.4 3.47e-6 Glucose homeostasis traits; TGCT cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg10862848 chr6:42927986 GNMT -0.38 -4.72 -0.39 6.35e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs950027 0.620 rs1153857 chr15:45659095 G/T cg26924012 chr15:45694286 SPATA5L1 0.79 8.86 0.62 6.92e-15 Response to fenofibrate (adiponectin levels); TGCT cis rs2153535 0.580 rs1577466 chr6:8444192 T/C cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs4366490 0.848 rs1939758 chr11:62903612 T/C cg21002970 chr11:62369079 MTA2 0.87 4.67 0.39 7.78e-6 Conotruncal heart defects; TGCT cis rs36051895 0.632 rs12337481 chr9:5134599 T/G cg02405213 chr9:5042618 JAK2 -0.75 -10.52 -0.69 6.97e-19 Pediatric autoimmune diseases; TGCT cis rs6547741 0.874 rs58737572 chr2:27852118 A/C cg27432699 chr2:27873401 GPN1 0.18 4.56 0.38 1.19e-5 Oral cavity cancer; TGCT cis rs9818758 0.607 rs3923475 chr3:49055788 G/T cg07636037 chr3:49044803 WDR6 -1.04 -5.16 -0.42 9.65e-7 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs11874712 1.000 rs56181324 chr18:43678024 G/A cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.04e-7 Migraine - clinic-based; TGCT cis rs7246657 0.943 rs10403613 chr19:37844306 C/T cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs9653442 0.510 rs11891046 chr2:100794402 C/G cg07810366 chr2:100720526 AFF3 -0.35 -5.25 -0.43 6.27e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2456568 0.805 rs2032400 chr11:93676937 G/A cg17595323 chr11:93583763 C11orf90 -0.45 -5.91 -0.47 3.1e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6448317 1.000 rs13105803 chr4:24940002 A/G cg21108841 chr4:24914750 CCDC149 -0.65 -4.94 -0.41 2.51e-6 Heschl's gyrus morphology; TGCT cis rs524023 0.958 rs3825016 chr11:64359286 C/T cg07733098 chr11:64478343 NRXN2 0.31 4.66 0.39 7.9e-6 Urate levels in obese individuals; TGCT cis rs655601 1.000 rs655601 chr5:180226673 G/T cg13724780 chr5:180237085 MGAT1 -0.82 -5.6 -0.45 1.3e-7 Quantitative traits; TGCT trans rs1814175 0.587 rs847628 chr11:49927064 A/T cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs13424612 0.930 rs6748327 chr2:240902511 G/A cg26363272 chr2:240904871 NDUFA10 0.3 5.01 0.41 1.82e-6 Odorant perception (isobutyraldehyde); TGCT cis rs2439831 0.541 rs12440854 chr15:43610672 A/G cg02155558 chr15:43621948 ADAL;LCMT2 1.12 7.38 0.55 1.97e-11 Lung cancer in ever smokers; TGCT cis rs2456568 0.805 rs2032400 chr11:93676937 G/A cg14065697 chr11:93583672 C11orf90 -0.37 -4.45 -0.37 1.87e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6570726 0.791 rs436498 chr6:145876347 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1046896 0.586 rs9897951 chr17:80810662 T/C cg03160526 chr17:80928410 B3GNTL1 0.33 4.57 0.38 1.18e-5 Glycated hemoglobin levels; TGCT cis rs1008375 0.932 rs9283698 chr4:17662471 T/C cg18681998 chr4:17616180 MED28 0.94 10.15 0.67 5.6e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11024102 1.000 rs4141194 chr11:17011176 A/C cg15378786 chr11:17036137 PLEKHA7 -0.48 -4.51 -0.38 1.48e-5 Glaucoma (primary angle closure); TGCT cis rs7044106 0.734 rs12553070 chr9:123485266 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.65 7.35 0.55 2.35e-11 Hip circumference adjusted for BMI; TGCT cis rs4975709 0.569 rs1684965 chr5:1865248 A/G cg12288994 chr5:1860383 NA 0.24 4.78 0.39 4.86e-6 Cardiovascular disease risk factors; TGCT cis rs2180341 0.618 rs11154398 chr6:127654281 C/A cg27446573 chr6:127587934 RNF146 0.65 5.79 0.46 5.52e-8 Breast cancer; TGCT cis rs1949733 1.000 rs3103072 chr4:8508431 C/T cg11789530 chr4:8429930 ACOX3 -0.63 -5.74 -0.46 6.71e-8 Response to antineoplastic agents; TGCT cis rs9640161 0.789 rs28432021 chr7:150046235 G/C cg17279839 chr7:150038598 RARRES2 0.43 4.64 0.38 8.89e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs10984561 0.881 rs7031568 chr9:122253548 C/T cg14242995 chr9:122249943 NA 0.74 6.01 0.47 1.96e-8 Pulmonary function decline; TGCT cis rs4455778 0.580 rs10242641 chr7:49085748 G/A cg26309511 chr7:48887640 NA 0.5 6.47 0.5 2.03e-9 Lung cancer in never smokers; TGCT cis rs3806843 0.576 rs155358 chr5:140297032 A/T cg07102913 chr5:140593443 PCDHB13 -0.48 -4.71 -0.39 6.57e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs6951245 0.542 rs28460147 chr7:1217192 G/A cg18402987 chr7:1209562 NA 0.76 6.35 0.5 3.62e-9 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7811142 1.000 rs73161762 chr7:100014846 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.04 -9.17 -0.64 1.27e-15 Platelet count; TGCT cis rs13108904 0.934 rs35201724 chr4:1310717 C/G cg13395646 chr4:1353034 KIAA1530 -0.5 -6.46 -0.5 2.15e-9 Obesity-related traits; TGCT cis rs7772486 0.536 rs9373467 chr6:145955605 C/T cg05347473 chr6:146136440 FBXO30 0.64 6.0 0.47 2.04e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs797680 0.789 rs35940311 chr1:93663604 G/A cg17826107 chr1:92977322 EVI5 -0.24 -5.31 -0.43 4.9e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7714584 0.793 rs11949375 chr5:150202980 T/C cg22134413 chr5:150180641 NA 0.89 6.96 0.53 1.73e-10 Crohn's disease; TGCT cis rs6788371 0.966 rs2059552 chr3:187318908 A/G cg01598596 chr3:187464648 BCL6 -0.44 -4.72 -0.39 6.38e-6 Pursuit maintenance gain; TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg11003573 chr3:44754125 ZNF502 -0.42 -4.72 -0.39 6.36e-6 Depressive symptoms; TGCT cis rs9443189 0.570 rs6903124 chr6:76290079 A/C cg01950844 chr6:76311363 SENP6 0.97 6.1 0.48 1.27e-8 Prostate cancer; TGCT cis rs611744 0.647 rs2597658 chr8:109256014 C/T cg21045802 chr8:109455806 TTC35 0.7 6.74 0.52 5.23e-10 Dupuytren's disease; TGCT cis rs7818688 0.697 rs78088250 chr8:95972718 G/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs4689388 0.929 rs1046320 chr4:6304344 C/T cg25554036 chr4:6271136 WFS1 0.5 6.75 0.52 5.02e-10 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs17376456 0.877 rs28575883 chr5:93346035 T/C cg25358565 chr5:93447407 FAM172A 0.97 8.5 0.61 5.11e-14 Diabetic retinopathy; TGCT cis rs9467773 0.595 rs3799379 chr6:26404694 C/T cg05738196 chr6:26577821 NA -0.5 -5.22 -0.42 7.31e-7 Intelligence (multi-trait analysis); TGCT cis rs10197940 0.662 rs4592848 chr2:152337822 G/A cg06191203 chr2:152266755 RIF1 -0.77 -7.27 -0.55 3.53e-11 Lung cancer; TGCT cis rs2153535 0.580 rs9505448 chr6:8459804 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9527 0.571 rs10786715 chr10:104620735 G/C cg15744005 chr10:104629667 AS3MT -0.5 -6.39 -0.5 3.12e-9 Arsenic metabolism; TGCT cis rs7772486 0.712 rs1292335 chr6:145967877 G/T cg23711669 chr6:146136114 FBXO30 0.65 6.22 0.49 6.92e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs1055129 0.560 rs2608880 chr17:73938957 C/T cg10935138 chr17:73851978 WBP2 0.55 4.87 0.4 3.35e-6 White matter hyperintensity burden; TGCT cis rs7113874 0.543 rs7935708 chr11:8478545 C/A cg14521421 chr11:8862019 ST5 0.29 4.49 0.37 1.59e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs11098499 0.909 rs1546502 chr4:120235898 A/G cg09307838 chr4:120376055 NA 0.61 5.68 0.45 8.88e-8 Corneal astigmatism; TGCT cis rs9902453 1.000 rs9891871 chr17:28370191 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -6.8 -0.52 3.85e-10 Coffee consumption (cups per day); TGCT cis rs35264875 1.000 rs6591370 chr11:68843003 G/A cg02660097 chr11:68866761 NA 0.32 4.87 0.4 3.4e-6 Blond vs. brown hair color; TGCT cis rs7914558 1.000 rs11191542 chr10:104824324 T/A cg15744005 chr10:104629667 AS3MT -0.38 -4.63 -0.38 9.1e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs35306767 0.903 rs12778891 chr10:950130 T/A cg26597838 chr10:835615 NA 0.75 10.3 0.68 2.42e-18 Eosinophil percentage of granulocytes; TGCT cis rs4654899 0.643 rs1408409 chr1:21089781 T/C cg01072550 chr1:21505969 NA -0.54 -8.83 -0.62 8.43e-15 Superior frontal gyrus grey matter volume; TGCT cis rs3806843 0.576 rs246002 chr5:140341104 A/G cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs2243480 0.708 rs35310401 chr7:65390359 A/G cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs1670533 0.585 rs6827206 chr4:1065071 A/T cg20887711 chr4:1340912 KIAA1530 0.69 5.5 0.44 2.03e-7 Recombination rate (females); TGCT cis rs9911578 0.933 rs74370218 chr17:57095212 C/T cg05425664 chr17:57184151 TRIM37 0.68 6.89 0.53 2.55e-10 Intelligence (multi-trait analysis); TGCT cis rs651907 0.557 rs35850993 chr3:101437433 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.68 0.39 7.44e-6 Colorectal cancer; TGCT cis rs9790314 0.905 rs6774276 chr3:160941318 C/T cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs7017914 0.870 rs34282253 chr8:71582366 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs3806843 0.676 rs778594 chr5:140027304 T/C cg19875535 chr5:140030758 IK -0.36 -6.34 -0.49 3.84e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs12477438 0.520 rs34252185 chr2:99737646 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 1.06 13.26 0.77 1.59e-25 Chronic sinus infection; TGCT cis rs12971120 0.891 rs11151961 chr18:72177340 C/T cg26446133 chr18:72167187 CNDP2 -0.35 -5.89 -0.47 3.42e-8 Refractive error; TGCT cis rs6921919 0.778 rs67381177 chr6:28411941 G/C cg10876282 chr6:28092338 ZSCAN16 0.86 4.46 0.37 1.8e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs2243480 chr7:65599196 C/T cg18252515 chr7:66147081 NA -1.25 -7.45 -0.56 1.37e-11 Diabetic kidney disease; TGCT cis rs2404602 0.618 rs12442266 chr15:76567142 T/C cg26408565 chr15:76604113 ETFA -0.47 -6.49 -0.5 1.86e-9 Blood metabolite levels; TGCT cis rs6540559 0.808 rs11119358 chr1:210042456 T/C cg10074409 chr1:209979377 IRF6 0.54 4.55 0.38 1.24e-5 Cleft lip with or without cleft palate; TGCT cis rs1577917 0.958 rs12202712 chr6:86578541 T/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.71e-7 Response to antipsychotic treatment; TGCT cis rs13191362 0.935 rs66923841 chr6:163177317 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.12 8.19 0.59 2.72e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs2241685 0.850 rs10865521 chr2:1943691 C/G cg21862353 chr2:1801628 MYT1L -0.48 -4.54 -0.38 1.31e-5 Attention deficit hyperactivity disorder; TGCT cis rs7586879 0.616 rs6726199 chr2:25126328 G/C cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT cis rs8014252 0.803 rs59233924 chr14:71050660 A/G cg11204974 chr14:71022665 NA -0.55 -4.54 -0.38 1.31e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs4733781 0.871 rs7839155 chr8:131318869 G/A cg16277922 chr8:131349729 ASAP1 0.36 4.66 0.39 7.92e-6 Tuberculosis; TGCT cis rs7523273 0.925 rs6540443 chr1:208002010 T/A cg22525895 chr1:207977042 MIR29B2 -0.49 -8.6 -0.61 2.98e-14 Schizophrenia; TGCT cis rs933688 0.938 rs7708782 chr5:90718517 T/C cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.98 8.36 0.6 1.11e-13 Smoking behavior; TGCT cis rs4746818 0.688 rs951718 chr10:70928044 A/G cg04149295 chr10:70884716 VPS26A 0.79 5.44 0.44 2.79e-7 Left atrial antero-posterior diameter; TGCT cis rs7829975 0.658 rs907181 chr8:8702875 T/C cg06636001 chr8:8085503 FLJ10661 0.7 6.49 0.5 1.82e-9 Mood instability; TGCT cis rs12579753 0.917 rs12316644 chr12:82205497 C/T cg07988820 chr12:82153109 PPFIA2 0.59 6.19 0.49 7.93e-9 Resting heart rate; TGCT cis rs7772486 0.655 rs2142981 chr6:146071695 G/C cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs13118159 0.934 rs4974553 chr4:1356911 G/A cg20887711 chr4:1340912 KIAA1530 0.54 4.77 0.39 5.11e-6 Longevity; TGCT cis rs62209 0.752 rs11256939 chr10:11009166 T/G cg26901096 chr10:10994189 LOC254312 0.43 6.99 0.53 1.46e-10 Alzheimer's disease (late onset); TGCT cis rs587847 0.558 rs627477 chr15:37684407 T/C cg16890051 chr15:37175029 LOC145845 -0.39 -4.57 -0.38 1.16e-5 Intraocular pressure; TGCT cis rs2243480 1.000 rs316325 chr7:65609518 G/A cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs9303401 0.659 rs3809724 chr17:57061238 G/A cg25039879 chr17:56429692 SUPT4H1 0.54 4.72 0.39 6.33e-6 Cognitive test performance; TGCT cis rs10504229 1.000 rs17217047 chr8:58180296 G/A cg21724239 chr8:58056113 NA 0.38 5.18 0.42 8.82e-7 Developmental language disorder (linguistic errors); TGCT cis rs427394 0.659 rs274693 chr5:6734162 G/A cg10857441 chr5:6722123 POLS -0.28 -6.08 -0.48 1.38e-8 Menopause (age at onset); TGCT cis rs10254284 0.959 rs757729 chr7:28146305 G/C cg23620719 chr7:28220237 JAZF1 -0.55 -4.93 -0.4 2.62e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs13256369 0.951 rs13260947 chr8:8565883 A/G cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs4654899 0.802 rs61781104 chr1:21257235 T/A cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs4975616 0.714 rs37007 chr5:1352372 G/C cg26373071 chr5:1325741 CLPTM1L 0.18 4.84 0.4 3.79e-6 Lung cancer; TGCT cis rs909674 0.524 rs5750821 chr22:39825492 A/T cg11247378 chr22:39784982 NA -0.73 -9.83 -0.66 3.22e-17 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs1008375 1.000 rs13106338 chr4:17676871 G/T cg16339924 chr4:17578868 LAP3 -0.61 -5.07 -0.41 1.38e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7193541 0.684 rs9929496 chr16:74668473 G/A cg01733217 chr16:74700730 RFWD3 1.0 13.52 0.77 3.8e-26 Multiple myeloma; TGCT cis rs9368481 0.743 rs9368480 chr6:26955750 A/C cg26531700 chr6:26746687 NA 0.51 4.52 0.38 1.44e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2243480 1.000 rs778704 chr7:65863467 T/C cg20637647 chr7:64974828 NA 0.9 5.31 0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg16325326 chr1:53192061 ZYG11B -0.73 -8.95 -0.63 4.41e-15 Monocyte count; TGCT cis rs727563 0.565 rs132774 chr22:42031953 C/G cg06634786 chr22:41940651 POLR3H -0.8 -7.63 -0.57 5.37e-12 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7267979 0.844 rs4423675 chr20:25402778 A/G cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs3780486 0.846 rs10813948 chr9:33121570 G/A cg20290983 chr6:43655470 MRPS18A 1.21 15.13 0.81 5.99e-30 IgG glycosylation; TGCT cis rs3858526 0.628 rs1840177 chr11:5944627 T/G cg13902645 chr11:5959945 NA 0.53 6.1 0.48 1.24e-8 DNA methylation (variation); TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg09704166 chr2:114031854 PAX8;LOC440839 -0.34 -4.96 -0.41 2.29e-6 Lymphocyte counts; TGCT cis rs13108904 0.967 rs12642396 chr4:1293055 C/A cg13342137 chr4:2252803 MXD4 0.17 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs3617 0.539 rs9880619 chr3:52953055 G/A cg10802521 chr3:52805072 NEK4 0.56 6.5 0.5 1.76e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7211079 0.879 rs61357240 chr17:78131775 A/G cg09238746 chr17:78121135 EIF4A3 -0.71 -5.87 -0.47 3.73e-8 Myocardial infarction; TGCT cis rs2235642 0.750 rs2859310 chr16:1656765 C/T cg10465839 chr16:1584050 IFT140;TMEM204 0.28 4.63 0.38 9.27e-6 Coronary artery disease; TGCT cis rs12497850 0.931 rs9867373 chr3:48960938 A/T cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs10782582 0.593 rs12142247 chr1:76235746 C/T cg22875332 chr1:76189707 ACADM -0.45 -4.93 -0.4 2.55e-6 Daytime sleep phenotypes; TGCT cis rs4242434 0.757 rs4872531 chr8:22529695 A/G cg03733263 chr8:22462867 KIAA1967 -1.04 -15.96 -0.82 7.59e-32 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2730245 0.505 rs1188956 chr7:158690576 G/A cg11984989 chr7:158649758 WDR60 0.99 8.9 0.62 5.65e-15 Height; TGCT cis rs9611565 1.000 rs5758314 chr22:41762523 T/G cg06634786 chr22:41940651 POLR3H -0.65 -6.21 -0.49 7.17e-9 Vitiligo; TGCT cis rs1862618 0.853 rs6450408 chr5:56098146 T/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs7731657 0.569 rs17621454 chr5:130205584 C/G cg08523029 chr5:130500466 HINT1 0.81 5.24 0.43 6.77e-7 Fasting plasma glucose; TGCT cis rs11792861 0.619 rs2289480 chr9:111705501 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.68 7.84 0.58 1.78e-12 Menarche (age at onset); TGCT cis rs807669 0.869 rs1061325 chr22:19184095 T/C cg02655711 chr22:19163373 SLC25A1 0.29 6.1 0.48 1.27e-8 Metabolite levels; TGCT cis rs2456568 0.695 rs55756119 chr11:93689909 A/G cg17595323 chr11:93583763 C11orf90 0.4 4.99 0.41 1.98e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs225245 0.791 rs7406966 chr17:34013636 A/C cg05299278 chr17:33885742 SLFN14 0.21 4.53 0.38 1.37e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs9486715 0.867 rs4598081 chr6:96975227 A/G cg18709589 chr6:96969512 KIAA0776 0.79 7.84 0.58 1.79e-12 Headache; TGCT cis rs9787249 0.957 rs6670841 chr1:40220284 C/G cg20968010 chr1:40505947 CAP1 -0.5 -4.7 -0.39 6.72e-6 Blood protein levels; TGCT cis rs2535633 0.820 rs7626551 chr3:52938092 C/G cg05573699 chr3:52720067 GNL3;PBRM1 0.52 5.06 0.41 1.48e-6 Body mass index; TGCT cis rs3809863 0.602 rs11650072 chr17:45393665 A/G cg08085267 chr17:45401833 C17orf57 -0.61 -7.05 -0.54 1.07e-10 Glaucoma (primary open-angle); TGCT cis rs7043114 0.525 rs9299404 chr9:95170338 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.53 5.44 0.44 2.73e-7 Height; TGCT cis rs10504229 0.679 rs12679920 chr8:58051710 G/T cg08219700 chr8:58056026 NA 0.29 4.45 0.37 1.91e-5 Developmental language disorder (linguistic errors); TGCT cis rs1008375 1.000 rs1121089 chr4:17676476 C/A cg18681998 chr4:17616180 MED28 0.89 10.2 0.68 4.06e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7781977 0.695 rs6583437 chr7:50350267 C/T cg01139861 chr7:50343298 IKZF1 0.49 5.9 0.47 3.22e-8 IgG glycosylation; TGCT cis rs7582180 0.677 rs11694723 chr2:100878122 C/T cg14675211 chr2:100938903 LONRF2 0.47 4.5 0.37 1.53e-5 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.614 rs3748930 chr2:101010082 G/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.77 -0.39 5.18e-6 Intelligence (multi-trait analysis); TGCT cis rs7914558 1.000 rs1926030 chr10:104855656 T/C cg15744005 chr10:104629667 AS3MT -0.42 -5.24 -0.43 6.69e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs13256369 0.756 rs13282580 chr8:8562903 C/T cg18904891 chr8:8559673 CLDN23 0.58 5.4 0.44 3.23e-7 Obesity-related traits; TGCT cis rs1018836 0.545 rs4236827 chr8:91688943 A/T cg16814680 chr8:91681699 NA -0.95 -13.83 -0.78 6.82e-27 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs62244186 0.520 rs9311361 chr3:44796132 T/G cg21672276 chr3:44754072 ZNF502 -0.53 -6.12 -0.48 1.14e-8 Depressive symptoms; TGCT cis rs4819052 1.000 rs2838830 chr21:46664227 T/G cg06618935 chr21:46677482 NA -0.37 -5.04 -0.41 1.64e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs8032315 0.965 rs35346340 chr15:91427872 G/C cg06330618 chr15:91428456 FES 0.19 4.68 0.39 7.42e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs28386778 0.897 rs2584608 chr17:61936710 A/G cg26338869 chr17:61819248 STRADA -0.57 -5.31 -0.43 4.81e-7 Prudent dietary pattern; TGCT cis rs7223966 1.000 rs78172786 chr17:61847114 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.58 4.62 0.38 9.61e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs10464366 0.957 rs6979210 chr7:39104119 C/G cg18850127 chr7:39170497 POU6F2 0.21 4.5 0.37 1.55e-5 IgG glycosylation; TGCT cis rs3540 0.574 rs2526000 chr15:90962626 C/T cg22089800 chr15:90895588 ZNF774 0.76 8.15 0.59 3.29e-13 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs1865760 0.566 rs9467663 chr6:26021456 C/G cg16482183 chr6:26056742 HIST1H1C 0.56 4.78 0.39 4.96e-6 Height; TGCT cis rs617219 0.671 rs6414979 chr5:78548010 T/G cg05890484 chr5:78407552 BHMT 0.38 5.17 0.42 9.01e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs873946 0.586 rs3793682 chr10:134564563 C/T cg26818010 chr10:134567672 INPP5A -0.38 -5.19 -0.42 8.5e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12477438 0.501 rs12619780 chr2:99707307 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 0.97 11.11 0.71 2.53e-20 Chronic sinus infection; TGCT cis rs4566357 0.930 rs13424003 chr2:227926860 G/A cg11843606 chr2:227700838 RHBDD1 -0.5 -4.49 -0.37 1.59e-5 Coronary artery disease; TGCT cis rs6095298 0.574 rs67763459 chr20:47464464 C/T cg12307787 chr20:48099359 KCNB1 0.42 4.54 0.38 1.32e-5 Intelligence (multi-trait analysis); TGCT cis rs28595532 0.841 rs114970257 chr4:119756937 G/A cg21605333 chr4:119757512 SEC24D 1.62 7.73 0.57 3.22e-12 Cannabis dependence symptom count; TGCT cis rs3924048 0.574 rs11589283 chr1:12612280 G/A cg00291366 chr1:12616550 NA 0.32 4.87 0.4 3.34e-6 Optic cup area; TGCT cis rs804280 0.525 rs1004712 chr8:11622293 C/T cg26752888 chr8:11627280 NEIL2 -0.57 -5.31 -0.43 4.9e-7 Myopia (pathological); TGCT cis rs2243480 1.000 rs35421653 chr7:65363429 C/A cg07424592 chr7:64974309 NA 1.38 8.17 0.59 3.04e-13 Diabetic kidney disease; TGCT cis rs2153535 0.580 rs7743686 chr6:8526111 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs12477438 0.765 rs1115756 chr2:99659845 C/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs7100689 0.646 rs10749573 chr10:82136839 T/A cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs9814567 1.000 rs62271515 chr3:134300507 T/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.91 -8.83 -0.62 8.17e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7267979 1.000 rs6083856 chr20:25407585 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5760092 0.755 rs6003959 chr22:24264395 C/T cg15242686 chr22:24348715 GSTTP1 -0.46 -5.33 -0.43 4.42e-7 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs3741404 0.825 rs2845597 chr11:63954370 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 0.9 10.24 0.68 3.38e-18 Platelet count; TGCT cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg05738196 chr6:26577821 NA 0.88 11.22 0.71 1.33e-20 Intelligence (multi-trait analysis); TGCT cis rs11122272 0.735 rs2474625 chr1:231519331 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs6089584 0.854 rs6061407 chr20:60622048 A/C cg06108461 chr20:60628389 TAF4 -0.69 -10.64 -0.69 3.59e-19 Body mass index; TGCT cis rs1372520 0.564 rs2737011 chr4:90746219 T/C cg20003494 chr4:90757398 SNCA -0.59 -4.63 -0.38 9.21e-6 Neuroticism; TGCT cis rs16854884 0.586 rs7611326 chr3:143736374 C/T cg06585982 chr3:143692056 C3orf58 0.57 4.61 0.38 9.92e-6 Economic and political preferences (feminism/equality); TGCT cis rs12497850 0.931 rs4974079 chr3:48906469 T/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs67478160 0.595 rs8022783 chr14:104245573 T/C cg26031613 chr14:104095156 KLC1 -0.64 -6.62 -0.51 9.86e-10 Schizophrenia; TGCT trans rs1814175 0.712 rs9665784 chr11:50030617 C/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg21724239 chr8:58056113 NA 0.52 5.53 0.44 1.8e-7 Developmental language disorder (linguistic errors); TGCT cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg02018176 chr4:1364513 KIAA1530 0.27 4.51 0.38 1.49e-5 Longevity; TGCT cis rs2762353 0.808 rs1165176 chr6:25830298 A/G cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.15e-6 Blood metabolite levels; TGCT cis rs9902453 0.791 rs9904051 chr17:28244122 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.92 9.1 0.63 1.88e-15 Coffee consumption (cups per day); TGCT cis rs7937612 0.965 rs11217840 chr11:120238655 A/G cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.61 -0.38 9.95e-6 Intraocular pressure; TGCT cis rs6009824 1.000 rs6009823 chr22:50086334 C/T cg27029450 chr22:50098074 NA 0.34 4.44 0.37 1.96e-5 Natriuretic peptide levels; TGCT cis rs6570726 0.791 rs6570694 chr6:145911204 C/G cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.45e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs7618501 0.521 rs34654589 chr3:49911449 C/G cg21659725 chr3:3221576 CRBN 0.69 7.72 0.57 3.29e-12 Intelligence (multi-trait analysis); TGCT cis rs1801251 1.000 rs6738386 chr2:233602028 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.45 0.5 2.22e-9 Coronary artery disease; TGCT cis rs55883249 1.000 rs75139639 chr2:9763905 A/T cg23886495 chr2:9695866 ADAM17 0.74 4.44 0.37 1.99e-5 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs610932 0.517 rs652303 chr11:59970047 C/T cg18570331 chr11:60101691 MS4A6E 0.51 4.69 0.39 7.12e-6 Alzheimer's disease; TGCT cis rs748404 0.631 rs560191 chr15:43767774 G/C cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.77 0.39 5.05e-6 Lung cancer; TGCT cis rs4319547 0.774 rs7954006 chr12:123131824 A/C cg05707623 chr12:122985044 ZCCHC8 0.65 5.53 0.44 1.79e-7 Body mass index; TGCT cis rs778371 1.000 rs11535 chr2:233743532 G/C cg08000102 chr2:233561755 GIGYF2 -0.59 -6.56 -0.51 1.29e-9 Schizophrenia; TGCT cis rs2050392 0.965 rs2265371 chr10:30690840 C/T cg18806716 chr10:30721971 MAP3K8 -0.44 -5.17 -0.42 9.28e-7 Inflammatory bowel disease; TGCT cis rs12497850 0.931 rs7636057 chr3:48992582 C/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.41 -0.44 3.09e-7 Parkinson's disease; TGCT cis rs79349575 0.783 rs28409394 chr17:46998118 T/C cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs10504229 0.516 rs60398072 chr8:58086559 G/A cg08219700 chr8:58056026 NA 0.35 6.19 0.49 8.15e-9 Developmental language disorder (linguistic errors); TGCT cis rs2380220 0.576 rs4498363 chr6:96042338 A/C cg04719120 chr6:96025338 MANEA 0.74 5.55 0.45 1.67e-7 Behavioural disinhibition (generation interaction); TGCT cis rs875971 0.516 rs6945322 chr7:65336056 T/C cg00343986 chr7:65444356 GUSB 0.26 6.11 0.48 1.18e-8 Aortic root size; TGCT cis rs79349575 0.783 rs12603969 chr17:47034419 A/G cg07967210 chr17:47022446 SNF8 0.44 6.15 0.48 9.98e-9 Type 2 diabetes; TGCT cis rs1005277 0.579 rs2505248 chr10:38459097 A/G cg25427524 chr10:38739819 LOC399744 -0.4 -8.1 -0.59 4.35e-13 Extrinsic epigenetic age acceleration; TGCT cis rs7681440 0.904 rs6816736 chr4:90765746 G/A cg26578617 chr4:90757533 SNCA -0.47 -4.87 -0.4 3.34e-6 Dementia with Lewy bodies; TGCT cis rs2836974 0.568 rs419469 chr21:40537234 C/T cg17971929 chr21:40555470 PSMG1 0.7 6.4 0.5 2.88e-9 Cognitive function; TGCT cis rs12908161 1.000 rs34570071 chr15:85280212 T/A cg17173187 chr15:85201210 NMB 0.59 6.57 0.51 1.22e-9 Schizophrenia; TGCT cis rs4820539 1.000 rs885965 chr22:23461425 A/G cg14186256 chr22:23484241 RTDR1 1.03 12.73 0.75 2.94e-24 Bone mineral density; TGCT cis rs6500602 0.893 rs6500596 chr16:4470027 G/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.42 6.31 0.49 4.45e-9 Schizophrenia; TGCT cis rs3751972 0.590 rs34256002 chr17:26272308 G/C cg02948944 chr17:26242737 NA -0.47 -5.45 -0.44 2.57e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs7666738 0.791 rs1896155 chr4:99020948 C/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs67311347 0.866 rs1454491 chr3:40352647 C/G cg13683864 chr3:40499215 RPL14 -0.9 -8.63 -0.61 2.55e-14 Renal cell carcinoma; TGCT cis rs2486288 0.656 rs11632651 chr15:45550838 C/T cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs7647973 0.626 rs1586827 chr3:49671224 T/C cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs17761864 1.000 rs17761864 chr17:2171637 G/T cg02171503 chr17:1588363 PRPF8 -0.49 -4.77 -0.39 5.06e-6 Esophageal cancer (squamous cell); TGCT cis rs2842992 0.789 rs7765490 chr6:160204326 C/T cg11366901 chr6:160182831 ACAT2 1.03 7.06 0.54 1.02e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs700590 0.723 rs700587 chr5:88110084 C/T cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.24e-7 Educational attainment (years of education); TGCT cis rs7611238 0.538 rs6794216 chr3:195100658 A/G cg27323046 chr3:195102265 ACAP2 0.39 5.17 0.42 8.93e-7 Body mass index; TGCT cis rs7246657 0.722 rs35863684 chr19:38109777 C/T cg03611452 chr19:38183253 ZNF781 0.57 4.55 0.38 1.28e-5 Coronary artery calcification; TGCT trans rs6089829 0.962 rs4586690 chr20:61658595 G/T cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT trans rs57221529 0.713 rs72703072 chr5:590626 A/G cg11887960 chr12:57824829 NA 1.17 9.7 0.66 6.57e-17 Lung disease severity in cystic fibrosis; TGCT cis rs3785574 0.962 rs2584630 chr17:61887561 T/A cg11494091 chr17:61959527 GH2 0.42 7.16 0.54 6.15e-11 Height; TGCT cis rs7226408 0.857 rs8084381 chr18:34597522 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs12681288 0.676 rs935820 chr8:1022168 A/G cg04851639 chr8:1020857 NA -0.35 -6.3 -0.49 4.66e-9 Schizophrenia; TGCT cis rs2178146 0.535 rs7195744 chr16:86454376 C/G cg11165158 chr16:86613094 FOXL1 0.36 4.71 0.39 6.57e-6 Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined);Esophageal adenocarcinoma; TGCT cis rs752010 0.714 rs2182606 chr1:42082375 T/C cg06885757 chr1:42089581 HIVEP3 0.25 4.45 0.37 1.92e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs1371867 0.846 rs2919469 chr8:101233896 C/T cg06636551 chr8:101224915 SPAG1 -0.5 -7.05 -0.53 1.12e-10 Atrioventricular conduction; TGCT cis rs2243480 1.000 rs7804223 chr7:65664559 T/G cg07424592 chr7:64974309 NA -1.27 -7.28 -0.55 3.29e-11 Diabetic kidney disease; TGCT cis rs7246657 0.722 rs16958863 chr19:38124235 A/G cg03611452 chr19:38183253 ZNF781 0.59 4.76 0.39 5.34e-6 Coronary artery calcification; TGCT cis rs2456568 0.802 rs10831136 chr11:93636860 T/C cg16099599 chr11:93583650 C11orf90 -0.4 -4.98 -0.41 2.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6750047 0.628 rs2855655 chr2:38304488 T/C cg07380506 chr2:38303506 CYP1B1 0.68 6.46 0.5 2.13e-9 Cutaneous malignant melanoma;Melanoma; TGCT cis rs2820315 0.928 rs2644111 chr1:201802052 G/A cg12730843 chr1:201915899 LMOD1 -0.26 -4.72 -0.39 6.26e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs12908161 1.000 rs12911736 chr15:85240008 A/G cg11189052 chr15:85197271 WDR73 0.75 6.3 0.49 4.8e-9 Schizophrenia; TGCT cis rs2629540 0.847 rs12247543 chr10:126419743 G/C cg08799069 chr10:126477246 METTL10 0.29 4.45 0.37 1.9e-5 Cocaine dependence; TGCT cis rs10927875 0.691 rs1048302 chr1:16340879 T/G cg22431228 chr1:16359049 CLCNKA -0.25 -4.77 -0.39 5.1e-6 Dilated cardiomyopathy; TGCT cis rs12533831 0.642 rs891508 chr7:150877774 A/G cg04712895 chr7:150801789 AGAP3 -0.2 -4.85 -0.4 3.66e-6 Childhood ear infection; TGCT cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg11301795 chr4:187892539 NA 0.34 5.13 0.42 1.09e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7226408 0.842 rs62083203 chr18:34352507 T/G cg06757138 chr18:34340585 FHOD3 0.3 5.26 0.43 6.01e-7 Obesity-related traits; TGCT cis rs9303401 0.614 rs2240719 chr17:56582477 G/C cg02118635 chr17:56770003 RAD51C;TEX14 0.63 6.36 0.5 3.54e-9 Cognitive test performance; TGCT cis rs4148883 0.629 rs10009145 chr4:100047929 G/A cg12011299 chr4:100065546 ADH4 0.4 6.08 0.48 1.4e-8 Alcohol dependence; TGCT cis rs7582180 0.739 rs4851292 chr2:100924761 A/G cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.86e-7 Intelligence (multi-trait analysis); TGCT cis rs3020736 0.500 rs6002605 chr22:42494335 A/G cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7312933 0.531 rs1796380 chr12:42791543 T/G cg11827402 chr12:42719852 PPHLN1;ZCRB1 -0.58 -5.7 -0.46 8.41e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs10751667 1.000 rs7927156 chr11:970607 A/G cg06064525 chr11:970664 AP2A2 -0.32 -5.95 -0.47 2.54e-8 Alzheimer's disease (late onset); TGCT cis rs270601 0.770 rs1007602 chr5:131602166 T/C cg12564285 chr5:131593104 PDLIM4 0.4 4.78 0.39 4.79e-6 Acylcarnitine levels; TGCT cis rs11122272 0.735 rs2808595 chr1:231526238 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.69 -6.58 -0.51 1.2e-9 Hemoglobin concentration; TGCT cis rs79349575 0.783 rs17708633 chr17:47011620 C/G cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs2798269 0.604 rs7325693 chr13:22163211 G/C cg18095732 chr13:22033692 ZDHHC20 -0.5 -4.46 -0.37 1.83e-5 PR segment; TGCT cis rs6831352 0.959 rs6848050 chr4:100053733 T/C cg12011299 chr4:100065546 ADH4 0.41 5.16 0.42 9.55e-7 Alcohol dependence; TGCT cis rs9427116 0.702 rs9427109 chr1:154609009 A/G cg17218026 chr1:154582156 ADAR 0.28 7.02 0.53 1.3e-10 Blood protein levels; TGCT cis rs1018836 0.828 rs10086462 chr8:91558089 A/G cg16814680 chr8:91681699 NA -0.75 -7.83 -0.58 1.82e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs73198271 0.813 rs17697237 chr8:8615874 A/C cg06671706 chr8:8559999 CLDN23 0.36 4.64 0.38 8.8e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12497850 1.000 rs4858798 chr3:48727112 C/T cg06212747 chr3:49208901 KLHDC8B 0.62 5.93 0.47 2.82e-8 Parkinson's disease; TGCT cis rs76473307 1.000 rs75507818 chr20:57419334 C/A cg06163629 chr20:57414884 GNASAS;GNAS -0.64 -4.5 -0.37 1.54e-5 Chronic lymphocytic leukemia; TGCT cis rs6840360 0.516 rs6535794 chr4:152302783 G/T cg17479576 chr4:152424074 FAM160A1 -0.55 -5.8 -0.46 5.23e-8 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.706 rs12701970 chr7:1121958 T/C cg04025307 chr7:1156635 C7orf50 0.23 5.33 0.43 4.46e-7 Longevity;Endometriosis; TGCT cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.98 10.67 0.69 2.97e-19 Intelligence (multi-trait analysis); TGCT cis rs2295359 0.963 rs12030867 chr1:67627620 T/C cg12940439 chr1:67600707 NA 0.53 5.59 0.45 1.36e-7 Psoriasis; TGCT cis rs11190604 0.945 rs2495746 chr10:102328270 T/C cg23241863 chr10:102295624 HIF1AN 0.67 5.1 0.42 1.23e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10197940 0.510 rs7602715 chr2:152421937 A/G cg06191203 chr2:152266755 RIF1 -0.64 -5.67 -0.45 9.57e-8 Lung cancer; TGCT cis rs10858047 0.883 rs975446 chr1:115187361 C/A cg12756093 chr1:115239321 AMPD1 -0.45 -4.73 -0.39 6.09e-6 Autism; TGCT cis rs9560113 0.960 rs9560102 chr13:112173825 G/A cg14154082 chr13:112174009 NA 0.34 4.67 0.39 7.79e-6 Menarche (age at onset); TGCT cis rs3820068 0.705 rs2145396 chr1:15875184 A/G cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs1878931 0.501 rs9635563 chr16:3416940 A/G cg22508957 chr16:3507546 NAT15 -0.38 -4.98 -0.41 2.1e-6 Body mass index (adult); TGCT cis rs35934224 0.783 rs6518585 chr22:19849501 C/T cg11182965 chr22:19864308 TXNRD2 -0.34 -4.51 -0.38 1.48e-5 Glaucoma (primary open-angle); TGCT cis rs651907 0.535 rs34648996 chr3:101511202 A/G cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT trans rs17685 0.625 rs1639630 chr7:75730499 T/C cg19862616 chr7:65841803 NCRNA00174 0.51 8.3 0.6 1.51e-13 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs736408 0.609 rs13061423 chr3:52790213 T/C cg10802521 chr3:52805072 NEK4 -0.73 -8.91 -0.62 5.5e-15 Bipolar disorder; TGCT cis rs1865760 0.568 rs2032450 chr6:25993114 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.72 6.94 0.53 1.97e-10 Height; TGCT cis rs61612642 0.523 rs59004693 chr6:42157392 G/A cg01092361 chr6:42185687 MRPS10 0.98 7.06 0.54 1.04e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs7507204 0.723 rs62125964 chr19:3414742 C/A cg08380311 chr19:3435252 NFIC 0.98 8.25 0.6 2e-13 Height; TGCT cis rs7085104 0.700 rs3740397 chr10:104592675 G/C cg05855489 chr10:104503620 C10orf26 0.52 4.62 0.38 9.64e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs9611519 0.780 rs2235850 chr22:41657626 C/T cg06634786 chr22:41940651 POLR3H -0.55 -4.98 -0.41 2.04e-6 Neuroticism; TGCT cis rs9486719 1.000 rs10872018 chr6:97026429 G/A cg18709589 chr6:96969512 KIAA0776 -0.71 -5.0 -0.41 1.9e-6 Migraine;Coronary artery disease; TGCT cis rs35883536 0.647 rs12043865 chr1:101042651 G/A cg06223162 chr1:101003688 GPR88 -0.42 -7.93 -0.58 1.1e-12 Monocyte count; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg20007245 chr22:24372913 LOC391322 -0.51 -4.75 -0.39 5.53e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10789491 0.953 rs11211337 chr1:47133811 T/C cg15501359 chr1:47185051 KIAA0494 0.84 8.52 0.61 4.48e-14 Response to hepatitis C treatment; TGCT cis rs1129187 0.934 rs9471974 chr6:42918984 T/A cg13397359 chr6:42928475 GNMT 0.74 6.83 0.52 3.33e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2982552 1.000 rs3020307 chr6:152067244 A/C cg22157087 chr6:152012887 ESR1 0.19 4.65 0.39 8.44e-6 Bone properties (heel); TGCT cis rs4072705 0.586 rs7855247 chr9:127246644 T/C cg13476313 chr9:127244764 NR5A1 -0.3 -5.18 -0.42 8.73e-7 Menarche (age at onset); TGCT cis rs7567389 0.504 rs13030463 chr2:128188871 G/A cg09760422 chr2:128146352 NA 0.34 4.51 0.38 1.46e-5 Self-rated health; TGCT cis rs17539620 0.624 rs111868524 chr6:154839960 G/C cg20019720 chr6:154832845 CNKSR3 0.56 4.78 0.39 4.84e-6 Lipoprotein (a) levels; TGCT cis rs9394841 0.646 rs9369313 chr6:41847065 C/T cg08135965 chr6:41755394 TOMM6 0.54 4.87 0.4 3.36e-6 Mean corpuscular hemoglobin;Red cell distribution width; TGCT cis rs1453308 1.000 rs1973040 chr2:237180199 A/G cg19324714 chr2:237145437 ASB18 0.57 5.09 0.42 1.3e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs589448 0.902 rs315131 chr12:69761839 T/G cg14784868 chr12:69753453 YEATS4 0.89 10.48 0.69 8.4e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs2147959 0.882 rs4653551 chr1:228627913 A/G cg22700015 chr1:228743131 NA 0.56 4.53 0.38 1.34e-5 Adult asthma; TGCT cis rs801193 0.569 rs2659893 chr7:66199993 G/A cg11764359 chr7:65958608 NA 0.54 4.79 0.4 4.68e-6 Aortic root size; TGCT cis rs9325144 0.560 rs2013804 chr12:38631079 C/T cg13010199 chr12:38710504 ALG10B -0.51 -4.52 -0.38 1.45e-5 Morning vs. evening chronotype; TGCT cis rs4689592 0.583 rs12501362 chr4:7083563 C/T cg25660036 chr4:7070649 GRPEL1 0.51 4.67 0.39 7.66e-6 Monocyte percentage of white cells; TGCT cis rs7726839 0.540 rs72703092 chr5:599269 G/A cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs8017423 1.000 rs8011810 chr14:90685669 A/G cg04374321 chr14:90722782 PSMC1 0.77 7.94 0.58 1.06e-12 Mortality in heart failure; TGCT cis rs17221829 0.702 rs72971023 chr11:89363934 A/G cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs12477438 0.765 rs62156363 chr2:99693324 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs6840360 1.000 rs4696109 chr4:152668785 A/C cg22705602 chr4:152727874 NA -0.24 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis); TGCT cis rs801193 1.000 rs2055682 chr7:66260289 A/G cg00343986 chr7:65444356 GUSB 0.21 4.58 0.38 1.11e-5 Aortic root size; TGCT cis rs11148252 0.595 rs4885117 chr13:53153027 T/C cg00495681 chr13:53174319 NA 0.64 6.42 0.5 2.68e-9 Lewy body disease; TGCT cis rs6840360 1.000 rs6535809 chr4:152592933 A/G cg17479576 chr4:152424074 FAM160A1 -0.5 -5.41 -0.44 3.18e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.679 rs16921688 chr8:58054659 T/C cg21724239 chr8:58056113 NA 0.44 4.81 0.4 4.36e-6 Developmental language disorder (linguistic errors); TGCT cis rs11741688 0.597 rs6880072 chr5:178334480 G/C cg08270223 chr5:178322770 ZFP2 -0.37 -5.49 -0.44 2.14e-7 Sleep duration; TGCT trans rs114540395 0.858 rs75820490 chr10:103253308 G/A cg10198749 chr1:39920707 MACF1 0.55 7.12 0.54 7.73e-11 Schizophrenia; TGCT cis rs6539288 0.500 rs11113116 chr12:107195929 C/A cg15890332 chr12:107067104 RFX4 0.28 5.53 0.44 1.8e-7 Total body bone mineral density; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg02073558 chr3:44770973 ZNF501 0.71 7.03 0.53 1.19e-10 Depressive symptoms; TGCT cis rs7017914 0.934 rs35109143 chr8:71577900 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs6671200 1.000 rs34037437 chr1:95660921 C/G cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs2361718 0.500 rs4889970 chr17:78096086 C/T cg22255288 chr17:78854418 RPTOR 0.26 4.56 0.38 1.2e-5 Yeast infection; TGCT cis rs7772486 0.686 rs4896827 chr6:145953338 T/A cg13319975 chr6:146136371 FBXO30 -0.52 -4.78 -0.39 4.81e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs1335628 chr6:8491742 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg19318889 chr4:1322082 MAEA 0.27 6.66 0.51 8.13e-10 Longevity; TGCT cis rs3785574 0.962 rs62077509 chr17:61848973 A/G cg01411255 chr17:61851458 DDX42;CCDC47 1.12 15.17 0.81 4.81e-30 Height; TGCT cis rs7677751 0.848 rs4635872 chr4:55099041 C/A cg17187183 chr4:55093834 PDGFRA 0.55 7.06 0.54 1.05e-10 Corneal astigmatism; TGCT trans rs1814175 0.754 rs28663627 chr11:50048829 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs9914988 0.887 rs12947735 chr17:27156866 A/T cg20469991 chr17:27169893 C17orf63 -0.74 -5.31 -0.43 4.83e-7 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs514406 0.679 rs960570 chr1:53237763 A/G cg24675658 chr1:53192096 ZYG11B 0.89 11.87 0.73 3.58e-22 Monocyte count; TGCT cis rs7917772 0.636 rs4418737 chr10:104525123 A/G cg05855489 chr10:104503620 C10orf26 0.67 5.32 0.43 4.77e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9976767 0.608 rs3746923 chr21:43826344 C/T cg23042151 chr21:43824109 UBASH3A -0.23 -5.14 -0.42 1.02e-6 Type 1 diabetes; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg20007245 chr22:24372913 LOC391322 -0.74 -7.45 -0.56 1.38e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7666738 0.791 rs7665273 chr4:98997413 C/A cg17366294 chr4:99064904 C4orf37 0.69 7.0 0.53 1.39e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7829975 0.606 rs10112585 chr8:8795030 A/T cg06636001 chr8:8085503 FLJ10661 -0.73 -6.58 -0.51 1.21e-9 Mood instability; TGCT cis rs13242816 0.881 rs12706091 chr7:116130783 G/C cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs2075371 0.965 rs2544216 chr7:133987902 G/A cg11752832 chr7:134001865 SLC35B4 0.69 6.32 0.49 4.25e-9 Mean platelet volume; TGCT trans rs8073060 0.586 rs4795086 chr17:34042190 G/A cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs2637266 1.000 rs7392737 chr10:78366059 C/T cg18941641 chr10:78392320 NA 0.4 4.73 0.39 6.03e-6 Pulmonary function; TGCT cis rs79387448 0.683 rs7571985 chr2:103147561 G/A cg09003973 chr2:102972529 NA 0.98 6.36 0.5 3.57e-9 Gut microbiota (bacterial taxa); TGCT cis rs9611565 0.694 rs202622 chr22:41825342 T/G cg03806693 chr22:41940476 POLR3H 1.16 13.41 0.77 7.02e-26 Vitiligo; TGCT cis rs4478858 0.611 rs1007012 chr1:31710068 G/A cg00250761 chr1:31883323 NA -0.28 -4.95 -0.41 2.42e-6 Alcohol dependence; TGCT cis rs1865760 0.663 rs9348704 chr6:26000393 A/C cg17042849 chr6:26104293 HIST1H4C -0.6 -5.38 -0.44 3.57e-7 Height; TGCT cis rs17221829 0.836 rs3931233 chr11:89451588 G/A cg02982614 chr11:89391479 FOLH1B -0.29 -5.09 -0.42 1.3e-6 Anxiety in major depressive disorder; TGCT cis rs9902453 0.834 rs9901694 chr17:28271645 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.9 8.55 0.61 3.78e-14 Coffee consumption (cups per day); TGCT cis rs2243480 1.000 rs73142162 chr7:65374296 A/T cg20637647 chr7:64974828 NA 0.94 5.17 0.42 9.06e-7 Diabetic kidney disease; TGCT cis rs1799949 0.965 rs1842147 chr17:41435192 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.18 0.42 8.74e-7 Menopause (age at onset); TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg21226059 chr5:178986404 RUFY1 -0.61 -7.2 -0.54 5.01e-11 Lung cancer; TGCT cis rs6545883 0.826 rs777591 chr2:61417617 A/G cg15711740 chr2:61764176 XPO1 -0.52 -4.45 -0.37 1.92e-5 Tuberculosis; TGCT cis rs10791097 0.694 rs3190331 chr11:130748131 C/T cg05962950 chr11:130786565 SNX19 -0.89 -11.3 -0.71 8.81e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6582630 0.519 rs11182457 chr12:38538331 G/A cg26384229 chr12:38710491 ALG10B 0.89 8.13 0.59 3.76e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs1887596 0.705 rs2454917 chr13:27227881 A/G cg01312412 chr13:27282625 NA 0.28 4.86 0.4 3.41e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs17270561 0.943 rs76703022 chr6:25703529 A/C cg17042849 chr6:26104293 HIST1H4C -0.69 -4.48 -0.37 1.64e-5 Iron status biomarkers; TGCT cis rs2180341 1.000 rs6569486 chr6:127708424 A/C cg27446573 chr6:127587934 RNF146 1.16 10.52 0.69 6.95e-19 Breast cancer; TGCT cis rs6089829 0.925 rs6122086 chr20:61664528 T/C cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7611238 0.583 rs4677826 chr3:195049539 C/A cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.94e-6 Body mass index; TGCT cis rs9676308 0.677 rs77420930 chr19:57639222 C/G cg25972591 chr19:58627987 ZSCAN18 -0.5 -4.47 -0.37 1.73e-5 Colorectal cancer; TGCT cis rs35146811 0.771 rs1060544 chr7:99613476 C/T cg13334819 chr7:99746414 C7orf59 -0.82 -7.38 -0.55 2.05e-11 Coronary artery disease; TGCT cis rs933688 1.000 rs2052553 chr5:90729906 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 8.86 0.62 7.17e-15 Smoking behavior; TGCT cis rs2404602 0.583 rs12592501 chr15:76554790 C/A cg26408565 chr15:76604113 ETFA -0.46 -6.46 -0.5 2.15e-9 Blood metabolite levels; TGCT cis rs6918586 0.615 rs198824 chr6:26122783 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.75 -0.52 4.96e-10 Schizophrenia; TGCT cis rs12681288 0.862 rs2701898 chr8:1020812 C/T cg04851639 chr8:1020857 NA -0.39 -7.59 -0.56 6.79e-12 Schizophrenia; TGCT cis rs10037670 0.557 rs2882673 chr5:153823066 G/C cg21964928 chr5:153872958 NA 0.26 4.7 0.39 6.68e-6 Behavioural disinhibition (generation interaction); TGCT cis rs2836974 0.568 rs7282604 chr21:40536910 C/T cg11890956 chr21:40555474 PSMG1 -0.78 -7.64 -0.57 5.14e-12 Cognitive function; TGCT cis rs951366 0.789 rs1772148 chr1:205704580 A/T cg14159672 chr1:205819179 PM20D1 0.6 7.44 0.56 1.45e-11 Menarche (age at onset); TGCT cis rs7953249 0.514 rs1169312 chr12:121441461 G/T cg02403541 chr12:121454288 C12orf43 0.66 6.26 0.49 5.61e-9 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs2439831 0.867 rs3213990 chr15:43670226 C/A cg02155558 chr15:43621948 ADAL;LCMT2 1.03 8.65 0.61 2.26e-14 Lung cancer in ever smokers; TGCT cis rs11098499 0.954 rs2389803 chr4:120393511 A/G cg09307838 chr4:120376055 NA -0.75 -7.0 -0.53 1.44e-10 Corneal astigmatism; TGCT cis rs9660992 0.573 rs1172158 chr1:205208948 G/A cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT trans rs7618501 0.633 rs2008877 chr3:50162291 T/G cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.19e-13 Intelligence (multi-trait analysis); TGCT cis rs9915657 0.687 rs2216169 chr17:70110419 G/A cg06234051 chr17:70120541 SOX9 -0.24 -5.0 -0.41 1.87e-6 Thyroid hormone levels; TGCT cis rs3947 0.789 rs9009 chr8:11702006 A/T cg02840367 chr8:11660030 FDFT1 -1.03 -8.54 -0.61 3.97e-14 Blood protein levels; TGCT cis rs10242455 0.571 rs41258334 chr7:99271808 T/C cg25640893 chr7:99214727 ZNF498 0.96 4.44 0.37 2e-5 Blood metabolite levels; TGCT cis rs6504663 0.558 rs2412325 chr17:48546232 G/C cg03168497 chr17:48586147 MYCBPAP 0.43 4.64 0.38 8.75e-6 Visceral fat; TGCT cis rs3771570 1.000 rs7557535 chr2:242206555 T/C cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs8031584 0.678 rs4779496 chr15:31151054 A/G cg14829155 chr15:31115871 NA -0.36 -4.72 -0.39 6.14e-6 Huntington's disease progression; TGCT cis rs896854 0.608 rs7004862 chr8:95876963 T/G cg23172400 chr8:95962367 TP53INP1 -0.29 -4.49 -0.37 1.61e-5 Type 2 diabetes; TGCT cis rs36051895 0.623 rs10975023 chr9:5239549 A/G cg02405213 chr9:5042618 JAK2 0.7 8.37 0.6 1e-13 Pediatric autoimmune diseases; TGCT cis rs2204008 0.747 rs11514040 chr12:38201040 G/A cg26384229 chr12:38710491 ALG10B 0.86 7.6 0.56 6.23e-12 Bladder cancer; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg23131131 chr22:24373011 LOC391322 0.57 4.54 0.38 1.3e-5 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs7568458 0.704 rs10176176 chr2:85762048 A/T cg17127132 chr2:85788382 GGCX 0.67 6.49 0.5 1.86e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6831352 0.918 rs7689753 chr4:100055575 A/G cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs806215 1.000 rs712700 chr7:127250907 T/C cg25922125 chr7:127225783 GCC1 0.59 5.98 0.47 2.21e-8 Type 2 diabetes; TGCT cis rs7267979 1.000 rs4815412 chr20:25350325 A/G cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1008375 0.932 rs6814465 chr4:17659034 C/T cg10189774 chr4:17578691 LAP3 0.55 4.83 0.4 3.89e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6570726 0.791 rs9403734 chr6:145931459 C/G cg23711669 chr6:146136114 FBXO30 0.89 9.63 0.65 1.01e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs3733585 0.699 rs4621431 chr4:9947590 C/T cg00071950 chr4:10020882 SLC2A9 -0.58 -6.72 -0.52 5.83e-10 Cleft plate (environmental tobacco smoke interaction); TGCT trans rs916888 0.610 rs199453 chr17:44800946 C/T cg22968622 chr17:43663579 NA 1.0 9.72 0.66 6.16e-17 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7027203 0.688 rs4075733 chr9:96624645 C/T cg14598338 chr9:96623480 NA -0.63 -10.08 -0.67 8.11e-18 DNA methylation (variation); TGCT cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs6570726 0.818 rs9399555 chr6:145877554 T/C cg05347473 chr6:146136440 FBXO30 0.52 4.87 0.4 3.37e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12681287 0.640 rs10086340 chr8:87446789 G/T cg27223183 chr8:87520930 FAM82B -0.86 -6.69 -0.51 6.88e-10 Caudate activity during reward; TGCT cis rs6665290 0.904 rs3795449 chr1:227181838 T/G cg10327440 chr1:227177885 CDC42BPA -0.98 -19.72 -0.87 4.93e-40 Myeloid white cell count; TGCT cis rs6674176 0.597 rs4660262 chr1:44382524 G/A cg12908607 chr1:44402522 ARTN -0.76 -9.58 -0.65 1.31e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs3858526 0.628 rs4237762 chr11:5956626 A/C cg13902645 chr11:5959945 NA -0.47 -5.74 -0.46 6.8e-8 DNA methylation (variation); TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs9611565 0.918 rs2281333 chr22:41749630 T/C cg13695892 chr22:41940480 POLR3H -0.85 -8.51 -0.61 4.83e-14 Vitiligo; TGCT cis rs9914988 0.887 rs62066838 chr17:27184533 C/T cg20469991 chr17:27169893 C17orf63 0.69 5.05 0.41 1.51e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs6665290 0.904 rs1343743 chr1:227183125 C/T cg10327440 chr1:227177885 CDC42BPA -0.98 -19.78 -0.87 3.72e-40 Myeloid white cell count; TGCT cis rs11718455 0.921 rs11130020 chr3:44009459 C/T cg08738300 chr3:44038990 NA 0.77 5.69 0.46 8.61e-8 Coronary artery disease; TGCT cis rs6840360 0.901 rs1946999 chr4:152455339 T/C cg17479576 chr4:152424074 FAM160A1 -0.55 -6.17 -0.48 8.74e-9 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg12419862 chr22:24373484 LOC391322 -0.81 -8.51 -0.61 4.7e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10644111 1 rs10644111 chr7:91652178 A/AAAC cg17063962 chr7:91808500 NA 0.91 9.97 0.67 1.53e-17 Breast cancer; TGCT cis rs910187 0.605 rs3787235 chr20:45803522 C/T cg27589058 chr20:45804311 EYA2 -0.38 -8.22 -0.59 2.25e-13 Migraine; TGCT cis rs11098499 0.779 rs28495013 chr4:120375831 A/C cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs2797160 0.935 rs1739372 chr6:126011325 G/A cg05901451 chr6:126070800 HEY2 0.72 6.11 0.48 1.18e-8 Endometrial cancer; TGCT cis rs56235845 0.694 rs11748912 chr5:176765395 G/A cg16006841 chr5:176797999 RGS14 0.5 7.45 0.56 1.38e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs3849570 0.696 rs13092157 chr3:81875332 T/A cg07356753 chr3:81810745 GBE1 -0.65 -5.97 -0.47 2.36e-8 Waist circumference;Body mass index; TGCT cis rs172166 0.694 rs203893 chr6:28062066 C/A cg10876282 chr6:28092338 ZSCAN16 0.51 4.79 0.39 4.75e-6 Cardiac Troponin-T levels; TGCT cis rs1757171 0.542 rs3818985 chr6:37484214 G/T cg01843034 chr6:37503916 NA -0.53 -7.06 -0.54 1.03e-10 Cognitive performance; TGCT cis rs60154123 0.505 rs77990373 chr1:210041111 T/C cg22029157 chr1:209979665 IRF6 0.79 5.78 0.46 5.6e-8 Coronary artery disease; TGCT cis rs13118159 0.550 rs4974617 chr4:1373658 T/C cg19318889 chr4:1322082 MAEA 0.28 6.74 0.52 5.27e-10 Longevity; TGCT cis rs12477438 0.520 rs2969379 chr2:99776686 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.32 0.85 4.52e-37 Chronic sinus infection; TGCT cis rs7786808 0.741 rs4909222 chr7:158228095 C/T cg01191920 chr7:158217561 PTPRN2 0.43 6.49 0.5 1.87e-9 Obesity-related traits; TGCT cis rs73198271 0.628 rs11781258 chr8:8589758 A/G ch.8.214553F chr8:8189620 PRAGMIN -0.32 -5.23 -0.42 7.04e-7 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7674212 0.507 rs223331 chr4:103793565 T/A cg16532752 chr4:104119610 CENPE -0.62 -5.59 -0.45 1.41e-7 Type 2 diabetes; TGCT cis rs4285028 0.948 rs12630486 chr3:121685267 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs992157 0.764 rs4423579 chr2:219185033 G/T cg00012203 chr2:219082015 ARPC2 0.7 6.58 0.51 1.16e-9 Colorectal cancer; TGCT cis rs7394190 0.688 rs3812629 chr10:75407290 G/A cg07699608 chr10:75541558 CHCHD1 0.62 4.63 0.38 9.08e-6 Incident atrial fibrillation; TGCT cis rs7605378 1.000 rs796363 chr2:200693668 T/C cg17644776 chr2:200775616 C2orf69 0.29 5.51 0.44 1.94e-7 Osteoporosis; TGCT cis rs7091068 0.518 rs4144097 chr10:95432480 A/C cg20715218 chr10:95462985 C10orf4 0.52 5.56 0.45 1.59e-7 Urinary tract infection frequency; TGCT cis rs3813567 0.759 rs12148319 chr15:78956192 A/G cg24631222 chr15:78858424 CHRNA5 0.69 4.79 0.4 4.66e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs4253772 0.550 rs9615347 chr22:46728153 A/G cg24881330 chr22:46731750 TRMU 0.96 4.79 0.4 4.65e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs11673344 0.503 rs703531 chr19:37500952 A/G cg08039142 chr19:36980659 ZNF566 0.52 4.84 0.4 3.71e-6 Obesity-related traits; TGCT cis rs763014 0.865 rs710924 chr16:633353 T/C cg27436995 chr16:743998 FBXL16 -0.46 -4.95 -0.41 2.35e-6 Height; TGCT cis rs5769707 0.777 rs8141219 chr22:50044546 A/G cg05373962 chr22:49881684 NA -0.33 -6.09 -0.48 1.3e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs2880765 0.835 rs4514633 chr15:86041017 T/G cg13263323 chr15:86062960 AKAP13 -0.22 -4.77 -0.39 5e-6 Coronary artery disease; TGCT cis rs1670533 0.932 rs4690347 chr4:1057328 A/G cg27284194 chr4:1044797 NA 0.67 5.79 0.46 5.37e-8 Recombination rate (females); TGCT cis rs9926296 0.542 rs12599531 chr16:89909401 C/T cg08627397 chr16:89984028 MC1R 0.34 5.15 0.42 1.01e-6 Vitiligo; TGCT cis rs1371867 0.846 rs1660316 chr8:101333049 T/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs72781680 0.800 rs72780112 chr2:23991182 C/T cg08917208 chr2:24149416 ATAD2B 0.83 5.24 0.43 6.62e-7 Lymphocyte counts; TGCT cis rs514406 0.929 rs515857 chr1:53336859 A/G cg08736216 chr1:53307985 ZYG11A -0.31 -6.14 -0.48 1.03e-8 Monocyte count; TGCT cis rs2115630 1.000 rs11073730 chr15:85354596 C/T cg12501888 chr15:85177176 SCAND2 -0.48 -4.49 -0.37 1.6e-5 P wave terminal force; TGCT cis rs986417 0.901 rs6573314 chr14:60972045 C/T cg27398547 chr14:60952738 C14orf39 1.41 9.11 0.63 1.75e-15 Gut microbiota (bacterial taxa); TGCT cis rs8072100 0.967 rs4794058 chr17:45597098 C/T cg08085267 chr17:45401833 C17orf57 0.44 4.89 0.4 3.12e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7805747 1.000 rs10480300 chr7:151406005 C/T cg17611936 chr7:151411526 PRKAG2 0.51 6.4 0.5 2.96e-9 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.830 rs2584625 chr17:61903445 G/C cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs9309473 0.514 rs62149630 chr2:73581755 C/G cg07208825 chr2:73871855 ALMS1P 0.27 5.11 0.42 1.21e-6 Metabolite levels; TGCT cis rs4566357 0.615 rs2894626 chr2:227916039 T/C cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs78487399 0.731 rs13395302 chr2:43706350 C/G cg03762820 chr2:43823654 THADA -0.48 -4.45 -0.37 1.88e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs12477438 1.000 rs12477438 chr2:99841085 T/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.97 -8.87 -0.62 6.77e-15 Chronic sinus infection; TGCT trans rs7698623 0.850 rs1982623 chr4:88790777 C/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs2204008 0.689 rs1581357 chr12:38391479 C/G cg13010199 chr12:38710504 ALG10B 0.58 4.59 0.38 1.05e-5 Bladder cancer; TGCT cis rs734999 0.870 rs2147905 chr1:2482921 C/T cg18854424 chr1:2615690 NA -0.45 -5.6 -0.45 1.31e-7 Ulcerative colitis; TGCT cis rs6940638 0.531 rs12211984 chr6:26986054 G/C cg26531700 chr6:26746687 NA 0.68 6.79 0.52 4.1e-10 Intelligence (multi-trait analysis); TGCT cis rs7428 0.527 rs1053560 chr2:85546192 C/T cg24342717 chr2:85555507 TGOLN2 -0.49 -8.1 -0.59 4.49e-13 Ear protrusion; TGCT cis rs4389656 0.857 rs274676 chr5:6754762 T/C cg10857441 chr5:6722123 POLS -0.21 -4.6 -0.38 1.03e-5 Coronary artery disease; TGCT cis rs7809950 1.000 rs10234355 chr7:107086517 T/G cg23024343 chr7:107201750 COG5 -0.35 -5.6 -0.45 1.34e-7 Coronary artery disease; TGCT cis rs1865760 0.566 rs10807006 chr6:26048752 C/A cg17042849 chr6:26104293 HIST1H4C -0.62 -5.41 -0.44 3.18e-7 Height; TGCT cis rs28386778 0.897 rs7210443 chr17:61785374 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.04 0.82 4.85e-32 Prudent dietary pattern; TGCT cis rs7829975 0.742 rs12547493 chr8:8661534 C/T cg15556689 chr8:8085844 FLJ10661 -0.68 -6.32 -0.49 4.37e-9 Mood instability; TGCT cis rs10504229 0.953 rs67677367 chr8:58175264 T/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs4149178 1.000 rs4149178 chr6:43272188 A/G cg12572677 chr6:43398225 ABCC10 0.31 4.8 0.4 4.47e-6 Urate levels; TGCT cis rs1629083 0.967 rs1715450 chr11:118128445 C/G cg16594165 chr11:118135105 MPZL2 0.33 4.62 0.38 9.32e-6 Lung cancer; TGCT cis rs910316 1.000 rs4903289 chr14:75623988 C/T cg08847533 chr14:75593920 NEK9 -0.98 -10.79 -0.7 1.55e-19 Height; TGCT cis rs7659604 0.702 rs6815790 chr4:122695385 A/C cg23574427 chr4:122746245 BBS7;CCNA2 -0.33 -5.26 -0.43 6.17e-7 Type 2 diabetes; TGCT cis rs9486719 1.000 rs12208449 chr6:96903253 A/G cg06623918 chr6:96969491 KIAA0776 0.87 7.38 0.55 1.96e-11 Migraine;Coronary artery disease; TGCT cis rs909674 0.541 rs5757655 chr22:39797178 C/G cg24399712 chr22:39784796 NA 1.06 13.4 0.77 7.31e-26 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs734999 0.545 rs10752748 chr1:2544640 G/A cg18854424 chr1:2615690 NA 0.44 5.15 0.42 1.01e-6 Ulcerative colitis; TGCT cis rs7914558 0.966 rs10748836 chr10:104693917 G/A cg15744005 chr10:104629667 AS3MT -0.41 -5.11 -0.42 1.16e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7666738 0.830 rs6833312 chr4:98951356 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 1.000 rs10883497 chr10:102228519 A/G cg16342193 chr10:102329863 NA -0.39 -5.26 -0.43 6.21e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs854765 0.547 rs2955359 chr17:17946730 T/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs10479542 0.892 rs7723230 chr5:178980474 T/C cg21226059 chr5:178986404 RUFY1 0.46 5.02 0.41 1.75e-6 Lung cancer; TGCT cis rs35000415 0.683 rs71581969 chr7:128722237 C/A cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs4285028 0.948 rs1920291 chr3:121672440 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs2243480 1.000 rs34637256 chr7:65360131 G/A cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT cis rs68170813 0.599 rs77878465 chr7:106890996 G/A cg02696742 chr7:106810147 HBP1 -0.66 -5.51 -0.44 1.94e-7 Coronary artery disease; TGCT cis rs11640734 0.609 rs11647746 chr16:89806343 C/A cg27121462 chr16:89883253 FANCA 0.78 4.65 0.39 8.51e-6 Interleukin-17 levels; TGCT cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg08392591 chr16:89556376 ANKRD11 0.56 5.24 0.43 6.83e-7 Multiple myeloma (IgH translocation); TGCT cis rs208520 0.690 rs10455595 chr6:66738034 T/C cg07460842 chr6:66804631 NA 0.94 9.91 0.66 2.15e-17 Exhaled nitric oxide output; TGCT cis rs12477438 0.520 rs34252185 chr2:99737646 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.89 9.0 0.63 3.26e-15 Chronic sinus infection; TGCT cis rs9291683 0.546 rs6820188 chr4:10051655 C/T cg11266682 chr4:10021025 SLC2A9 0.6 7.56 0.56 7.72e-12 Bone mineral density; TGCT cis rs2299587 0.554 rs2073565 chr8:17743649 T/C cg04898035 chr8:17640624 MTUS1 -0.2 -4.67 -0.39 7.77e-6 Economic and political preferences; TGCT cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs34891900 0.507 rs738133 chr22:18205557 C/T cg19898043 chr22:18121309 BCL2L13 0.55 4.74 0.39 5.77e-6 Sum neutrophil eosinophil counts; TGCT cis rs4478858 0.735 rs10914361 chr1:31817542 T/G cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9788682 0.947 rs7169584 chr15:78822660 A/T cg24631222 chr15:78858424 CHRNA5 0.93 7.96 0.58 9.55e-13 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs7959452 0.590 rs11177628 chr12:69765421 G/A cg20891283 chr12:69753455 YEATS4 0.83 8.61 0.61 2.8e-14 Blood protein levels; TGCT cis rs2019216 0.500 rs1356483 chr17:21934029 A/C cg22648282 chr17:21454238 C17orf51 -0.6 -5.51 -0.44 1.98e-7 Pelvic organ prolapse; TGCT cis rs7208859 0.673 rs73263981 chr17:28920502 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs941408 0.964 rs1736194 chr19:2786397 C/G cg06609049 chr19:2785107 THOP1 0.85 7.87 0.58 1.47e-12 Total cholesterol levels; TGCT cis rs4665809 0.590 rs34728554 chr2:26481959 C/G cg26119090 chr2:26468346 HADHA;HADHB 1.0 7.42 0.55 1.64e-11 Gut microbiome composition (summer); TGCT cis rs10782582 0.593 rs12142247 chr1:76235746 C/T cg10523679 chr1:76189770 ACADM -0.61 -6.13 -0.48 1.09e-8 Daytime sleep phenotypes; TGCT cis rs9926296 0.568 rs1230 chr16:89804855 A/G cg27121462 chr16:89883253 FANCA -0.81 -8.83 -0.62 8.24e-15 Vitiligo; TGCT cis rs6570726 0.846 rs7762536 chr6:145923145 T/C cg13319975 chr6:146136371 FBXO30 -0.53 -4.79 -0.4 4.6e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1692580 0.840 rs262679 chr1:2169792 C/T cg24578937 chr1:2090814 PRKCZ 0.24 5.35 0.43 4.12e-7 Coronary artery disease; TGCT cis rs7666738 0.830 rs6811940 chr4:98777898 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.75 0.46 6.46e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1799949 0.965 rs9646418 chr17:41425901 A/G cg05368731 chr17:41323189 NBR1 1.03 11.58 0.72 1.83e-21 Menopause (age at onset); TGCT cis rs2153535 0.580 rs718503 chr6:8527463 A/T cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.49e-8 Motion sickness; TGCT cis rs7507204 0.723 rs12982194 chr19:3411947 G/A cg08380311 chr19:3435252 NFIC 0.97 8.2 0.59 2.59e-13 Height; TGCT cis rs7843479 1.000 rs7821592 chr8:21811530 C/G cg17168535 chr8:21777572 XPO7 0.63 5.75 0.46 6.56e-8 Mean corpuscular volume; TGCT cis rs7809950 0.911 rs1015411 chr7:107135612 C/T cg23024343 chr7:107201750 COG5 -0.35 -5.5 -0.44 2.05e-7 Coronary artery disease; TGCT cis rs10779751 1.000 rs7526649 chr1:11278163 C/T cg08854313 chr1:11322531 MTOR 0.95 8.99 0.63 3.52e-15 Body mass index; TGCT cis rs1797081 1.000 rs2603807 chr10:16872797 A/G cg23933602 chr10:16859644 RSU1 1.07 13.21 0.76 2.04e-25 Platelet distribution width; TGCT cis rs72781680 1.000 rs115861480 chr2:24129464 T/A cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs5750830 0.595 rs4821892 chr22:39795683 G/C cg01416388 chr22:39784598 NA -0.72 -7.04 -0.53 1.18e-10 Intelligence (multi-trait analysis); TGCT cis rs7191439 0.626 rs8059794 chr16:88787388 C/T cg27087555 chr16:88793112 FAM38A -0.46 -5.5 -0.44 2.11e-7 Plateletcrit; TGCT trans rs7618501 0.633 rs2252833 chr3:50004209 C/T cg21659725 chr3:3221576 CRBN 0.75 8.79 0.62 1.06e-14 Intelligence (multi-trait analysis); TGCT cis rs875971 0.825 rs59466412 chr7:65565358 A/G cg11764359 chr7:65958608 NA -0.55 -4.7 -0.39 6.77e-6 Aortic root size; TGCT cis rs60843830 1.000 rs62114544 chr2:269679 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.73 7.41 0.55 1.74e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs617219 0.710 rs2255913 chr5:78562399 G/C cg23514016 chr5:78407564 BHMT 0.32 4.87 0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs896854 0.517 rs9643353 chr8:95957063 A/G cg16049864 chr8:95962084 TP53INP1 0.54 6.01 0.48 1.9e-8 Type 2 diabetes; TGCT cis rs2288278 0.601 rs60859312 chr17:46599035 C/T cg25032089 chr17:46643351 HOXB3 -0.42 -5.01 -0.41 1.86e-6 Hand grip strength; TGCT cis rs858239 0.600 rs6461691 chr7:23139345 G/A cg05602783 chr7:23145260 KLHL7 -0.73 -6.3 -0.49 4.74e-9 Cerebrospinal fluid biomarker levels; TGCT cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg22535103 chr8:58192502 C8orf71 -0.4 -5.06 -0.41 1.44e-6 Developmental language disorder (linguistic errors); TGCT cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg16145915 chr7:1198662 ZFAND2A -0.62 -8.8 -0.62 9.71e-15 Longevity;Endometriosis; TGCT cis rs4653767 0.573 rs708772 chr1:226912891 A/G cg26513734 chr1:225996982 EPHX1 0.16 4.52 0.38 1.4e-5 Parkinson's disease; TGCT cis rs7647973 1.000 rs62261249 chr3:49594060 T/C cg07636037 chr3:49044803 WDR6 -0.68 -5.5 -0.44 2.09e-7 Menarche (age at onset); TGCT cis rs9902453 0.845 rs2321331 chr17:28025528 G/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs651907 0.557 rs3094297 chr3:101399260 A/G cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.6 6.1 0.48 1.27e-8 Colorectal cancer; TGCT cis rs1799949 1.000 rs11657835 chr17:41291953 C/G cg05368731 chr17:41323189 NBR1 1.17 13.8 0.78 7.84e-27 Menopause (age at onset); TGCT cis rs7647973 0.580 rs4955432 chr3:49266772 C/T cg16497277 chr3:49208875 KLHDC8B -0.55 -5.25 -0.43 6.31e-7 Menarche (age at onset); TGCT cis rs4499344 0.657 rs2868146 chr19:33050047 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.21 -0.49 7.33e-9 Mean platelet volume; TGCT cis rs7666738 0.544 rs35160902 chr4:98974690 A/T cg17366294 chr4:99064904 C4orf37 0.69 6.93 0.53 2.03e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3087591 0.960 rs12939815 chr17:29430916 G/C cg24425628 chr17:29625626 OMG;NF1 0.47 7.16 0.54 6.19e-11 Hip circumference; TGCT cis rs1862618 0.802 rs252900 chr5:56185281 T/A cg03609598 chr5:56110824 MAP3K1 -0.59 -4.78 -0.39 4.81e-6 Initial pursuit acceleration; TGCT cis rs6558530 0.730 rs4875958 chr8:1721090 A/G cg09410841 chr8:1729607 CLN8 -0.78 -8.76 -0.62 1.22e-14 Systolic blood pressure; TGCT cis rs11874712 1.000 rs28699609 chr18:43674879 A/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.23 0.42 7.11e-7 Migraine - clinic-based; TGCT cis rs9611565 0.659 rs4822035 chr22:41935912 A/G cg06634786 chr22:41940651 POLR3H 0.87 8.49 0.61 5.3e-14 Vitiligo; TGCT cis rs858239 0.539 rs6965833 chr7:23192366 T/C cg05602783 chr7:23145260 KLHL7 -0.63 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs4665809 1.000 rs6546768 chr2:26328800 A/G cg22920501 chr2:26401640 FAM59B -0.72 -6.38 -0.5 3.19e-9 Gut microbiome composition (summer); TGCT cis rs651907 0.557 rs2288272 chr3:101378476 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.79 0.7 1.52e-19 Colorectal cancer; TGCT cis rs7647973 1.000 rs9842132 chr3:49427933 G/A cg07636037 chr3:49044803 WDR6 -0.72 -5.79 -0.46 5.35e-8 Menarche (age at onset); TGCT cis rs12477438 0.700 rs10190421 chr2:99670711 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs4746818 0.901 rs10740317 chr10:70937566 G/A cg11621586 chr10:70884670 VPS26A 1.1 7.75 0.57 2.8e-12 Left atrial antero-posterior diameter; TGCT cis rs4253772 0.678 rs1053332 chr22:46640179 A/G cg09491104 chr22:46646882 C22orf40 -0.48 -4.9 -0.4 2.9e-6 LDL cholesterol;Cholesterol, total; TGCT cis rs2439831 0.850 rs68079546 chr15:44136957 G/T cg02155558 chr15:43621948 ADAL;LCMT2 0.89 6.2 0.49 7.73e-9 Lung cancer in ever smokers; TGCT cis rs7296418 0.922 rs1727293 chr12:123648032 C/T cg05973401 chr12:123451056 ABCB9 0.55 4.53 0.38 1.39e-5 Platelet count; TGCT cis rs4665809 1.000 rs1560868 chr2:26281459 A/T cg04944784 chr2:26401820 FAM59B 0.63 5.85 0.46 4.13e-8 Gut microbiome composition (summer); TGCT cis rs9393692 0.905 rs9393693 chr6:26277408 C/A cg00631329 chr6:26305371 NA -0.41 -6.09 -0.48 1.34e-8 Educational attainment; TGCT cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg06108461 chr20:60628389 TAF4 -0.74 -10.73 -0.69 2.07e-19 Body mass index; TGCT cis rs7027203 0.595 rs4308796 chr9:96570165 G/A cg13679303 chr9:96623674 NA 0.55 7.77 0.57 2.54e-12 DNA methylation (variation); TGCT cis rs9814567 1.000 rs1534025 chr3:134313304 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 8.76 0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7267979 0.844 rs4423675 chr20:25402778 A/G cg16686733 chr20:25566563 NINL -0.52 -4.93 -0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6901004 0.803 rs402014 chr6:111527696 C/T cg15721981 chr6:111408429 SLC16A10 -0.51 -4.5 -0.37 1.56e-5 Blood metabolite levels; TGCT cis rs910316 1.000 rs4903284 chr14:75592483 G/C cg23033748 chr14:75592666 NEK9 0.29 4.9 0.4 2.95e-6 Height; TGCT cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg03517284 chr6:25882590 NA 0.68 6.25 0.49 6.06e-9 Intelligence (multi-trait analysis); TGCT cis rs78487399 0.710 rs79625619 chr2:43594483 A/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.73 4.48 0.37 1.65e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7945705 0.902 rs10743095 chr11:8936984 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.47 5.29 0.43 5.36e-7 Hemoglobin concentration; TGCT cis rs9372498 0.536 rs72969531 chr6:118729974 C/A cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs1865760 0.827 rs9295680 chr6:25944103 T/C cg17042849 chr6:26104293 HIST1H4C -0.5 -4.55 -0.38 1.27e-5 Height; TGCT cis rs763121 0.853 rs9610993 chr22:39042818 C/A cg06022373 chr22:39101656 GTPBP1 0.74 7.14 0.54 7.09e-11 Menopause (age at onset); TGCT cis rs9894429 1.000 rs35435780 chr17:79579602 G/T cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs9311474 0.508 rs6788887 chr3:52605005 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Electroencephalogram traits; TGCT trans rs11764590 0.715 rs9969125 chr7:2088460 C/T cg25206134 chr2:45395956 NA 0.97 6.72 0.52 5.86e-10 Neuroticism; TGCT cis rs611744 0.647 rs12675265 chr8:109268805 C/T cg21045802 chr8:109455806 TTC35 0.71 7.25 0.55 4.03e-11 Dupuytren's disease; TGCT cis rs6752107 1.000 rs34123137 chr2:234167881 T/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.88 0.4 3.17e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs7394190 0.748 rs11000772 chr10:75533988 T/G cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg12310025 chr6:25882481 NA -0.66 -6.0 -0.47 2.02e-8 Intelligence (multi-trait analysis); TGCT cis rs7582180 0.700 rs11685293 chr2:100976502 A/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.98 -0.41 2.1e-6 Intelligence (multi-trait analysis); TGCT cis rs2032447 0.798 rs807212 chr6:26065621 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.6 -6.02 -0.48 1.84e-8 Intelligence (multi-trait analysis); TGCT cis rs116095464 0.558 rs56043030 chr5:220917 A/G cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs1042445 1.000 rs1042445 chr3:186395436 C/T cg13908232 chr3:186371902 NA 0.46 5.23 0.43 6.94e-7 Blood protein levels; TGCT cis rs4319547 0.614 rs10846764 chr12:122874297 T/C cg05707623 chr12:122985044 ZCCHC8 0.62 4.87 0.4 3.32e-6 Body mass index; TGCT cis rs686320 1.000 rs72643572 chr11:65250967 A/G cg21890820 chr11:65308645 LTBP3 0.8 5.05 0.41 1.51e-6 Hip circumference adjusted for BMI; TGCT cis rs986417 0.901 rs2351171 chr14:61000322 T/C cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs28374715 0.662 rs10851403 chr15:41466087 T/G cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.41 -0.72 4.6e-21 Ulcerative colitis; TGCT cis rs12478296 0.786 rs55876934 chr2:243033816 C/T cg06360820 chr2:242988706 NA -0.58 -4.47 -0.37 1.76e-5 Obesity-related traits; TGCT cis rs1048238 0.506 rs56352596 chr1:16297592 G/A cg22431228 chr1:16359049 CLCNKA -0.23 -4.57 -0.38 1.18e-5 Systolic blood pressure; TGCT cis rs11122272 0.705 rs2486731 chr1:231532511 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.67 6.5 0.5 1.74e-9 Hemoglobin concentration; TGCT cis rs12368653 0.607 rs7966795 chr12:58031413 C/A cg12615879 chr12:58013172 SLC26A10 0.59 7.2 0.54 5.18e-11 Multiple sclerosis; TGCT trans rs9929218 0.551 rs3785135 chr16:68728976 A/C cg04657470 chr2:198365150 HSPE1;HSPD1 -0.58 -7.69 -0.57 4.02e-12 Colorectal cancer; TGCT cis rs2742417 0.967 rs2742439 chr3:45744248 G/A cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7666738 0.753 rs1527520 chr4:98929164 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6138458 0.828 rs6138466 chr20:24997137 A/G cg26195577 chr20:24973756 C20orf3 1.04 9.62 0.65 1.04e-16 Blood protein levels; TGCT cis rs7811142 0.830 rs78256546 chr7:99952970 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.88 7.12 0.54 7.55e-11 Platelet count; TGCT cis rs9372498 0.536 rs77435770 chr6:118819467 G/A cg07617317 chr6:118971624 C6orf204 0.46 5.08 0.41 1.36e-6 Diastolic blood pressure; TGCT cis rs13256369 0.802 rs1060107 chr8:8561399 G/T cg17143192 chr8:8559678 CLDN23 0.55 5.13 0.42 1.1e-6 Obesity-related traits; TGCT cis rs1552244 0.872 rs35988239 chr3:10074145 G/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.42 -4.47 -0.37 1.72e-5 Alzheimer's disease; TGCT cis rs1570884 0.516 rs9526580 chr13:50164023 C/G cg08779649 chr13:50194554 NA -0.4 -6.38 -0.5 3.12e-9 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs7044106 0.708 rs10760113 chr9:123474050 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.35 0.5 3.69e-9 Hip circumference adjusted for BMI; TGCT cis rs2948294 0.588 rs7011221 chr8:8114246 C/T cg06636001 chr8:8085503 FLJ10661 0.82 7.11 0.54 7.94e-11 Red cell distribution width; TGCT cis rs2982552 0.773 rs11155809 chr6:152056058 A/G cg22157087 chr6:152012887 ESR1 0.21 5.17 0.42 8.93e-7 Bone properties (heel); TGCT trans rs797680 0.856 rs531358 chr1:93676011 C/T cg27528825 chr2:159282178 CCDC148 -0.35 -6.88 -0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1524927 1.000 rs12704872 chr7:96334616 T/C cg03808172 chr7:96339361 SHFM1 0.49 5.06 0.41 1.45e-6 Total body bone mineral density; TGCT cis rs922182 0.557 rs2004231 chr15:64195769 C/T cg02919090 chr15:64263738 DAPK2 0.37 7.05 0.53 1.09e-10 Blood protein levels; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg15242686 chr22:24348715 GSTTP1 0.44 5.98 0.47 2.23e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9443645 0.810 rs9361482 chr6:79750385 T/C cg09184832 chr6:79620586 NA -0.45 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs56091001 0.528 rs9616387 chr22:50313219 G/A cg02269571 chr22:50332266 NA -0.35 -4.44 -0.37 1.97e-5 Acne (severe); TGCT cis rs1865760 0.865 rs9467647 chr6:25957642 A/G cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs2282802 0.758 rs739954 chr5:139701920 C/T cg01081189 chr5:139537190 NA 0.25 4.53 0.38 1.37e-5 Intelligence (multi-trait analysis); TGCT cis rs17376456 0.569 rs1026279 chr5:93209581 C/A cg21475434 chr5:93447410 FAM172A -0.68 -5.22 -0.42 7.16e-7 Diabetic retinopathy; TGCT cis rs137699 0.604 rs137702 chr22:39750158 T/C cg05872129 chr22:39784769 NA -0.73 -5.64 -0.45 1.1e-7 IgG glycosylation; TGCT cis rs17665859 0.925 rs35475931 chr8:481500 C/G cg17960703 chr8:356704 FBXO25 1.2 4.7 0.39 6.74e-6 Bilirubin levels; TGCT cis rs2486012 0.649 rs9726489 chr1:44267668 G/C cg12908607 chr1:44402522 ARTN -0.71 -5.54 -0.45 1.75e-7 Intelligence (multi-trait analysis); TGCT cis rs10823500 0.604 rs10762345 chr10:71939374 A/G cg04118878 chr10:71993077 PPA1 0.48 4.86 0.4 3.51e-6 Blood protein levels; TGCT cis rs6586111 0.904 rs6586105 chr10:82372248 A/G cg03086067 chr10:82368399 SH2D4B -0.24 -4.7 -0.39 6.84e-6 Capecitabine sensitivity; TGCT cis rs2204008 0.837 rs11611861 chr12:38357459 A/G cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg22105103 chr4:187893119 NA 0.31 4.44 0.37 1.98e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs8072100 0.817 rs6505049 chr17:45675781 G/A cg08085267 chr17:45401833 C17orf57 0.47 4.99 0.41 1.96e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs9611565 0.506 rs1984839 chr22:41685937 G/C cg03806693 chr22:41940476 POLR3H -0.81 -7.72 -0.57 3.26e-12 Vitiligo; TGCT cis rs3820928 0.874 rs4675138 chr2:227884118 G/A cg11843606 chr2:227700838 RHBDD1 -0.58 -5.35 -0.43 4e-7 Pulmonary function; TGCT cis rs3749237 0.615 rs55957735 chr3:49438158 G/A cg07636037 chr3:49044803 WDR6 0.64 6.04 0.48 1.63e-8 Resting heart rate; TGCT cis rs8072100 0.869 rs4439799 chr17:45781599 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.51 -0.44 1.98e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs10504229 0.906 rs7846666 chr8:58172302 T/C cg24829409 chr8:58192753 C8orf71 -0.52 -5.02 -0.41 1.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs7312933 0.701 rs10880260 chr12:42561398 A/G cg19980929 chr12:42632907 YAF2 0.46 6.3 0.49 4.75e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs4746818 1.000 rs7476357 chr10:70935660 G/A cg11621586 chr10:70884670 VPS26A 1.21 10.5 0.69 7.7e-19 Left atrial antero-posterior diameter; TGCT cis rs2762353 0.935 rs1165195 chr6:25815080 T/G cg12310025 chr6:25882481 NA -0.55 -5.59 -0.45 1.4e-7 Blood metabolite levels; TGCT trans rs1814175 0.817 rs1988416 chr11:49932324 G/A cg15704280 chr7:45808275 SEPT13 -0.71 -8.0 -0.58 7.45e-13 Height; TGCT cis rs9611565 0.694 rs19573 chr22:41865809 C/A cg13695892 chr22:41940480 POLR3H 0.93 9.1 0.63 1.91e-15 Vitiligo; TGCT cis rs1215050 0.740 rs10025482 chr4:99053277 T/C cg17366294 chr4:99064904 C4orf37 0.59 6.26 0.49 5.68e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs737008 1.000 rs737008 chr16:11374866 G/T cg00044050 chr16:11439710 C16orf75 -0.7 -6.92 -0.53 2.13e-10 Obesity-related traits; TGCT cis rs1395 0.922 rs4665376 chr2:27509032 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.47 6.18 0.49 8.53e-9 Blood metabolite levels; TGCT cis rs4253772 0.591 rs73886791 chr22:46687212 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 5.27 0.43 5.83e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs9733 0.519 rs2184833 chr1:150675483 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.81 0.4 4.38e-6 Tonsillectomy; TGCT cis rs7618915 0.501 rs34754793 chr3:52629177 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs6964587 0.626 rs34404183 chr7:91551249 T/C cg17063962 chr7:91808500 NA -0.76 -7.25 -0.55 3.94e-11 Breast cancer; TGCT cis rs765787 0.530 rs11070444 chr15:45513121 T/C cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT trans rs2727020 0.729 rs10839283 chr11:49490943 T/C cg15704280 chr7:45808275 SEPT13 0.71 7.95 0.58 9.76e-13 Coronary artery disease; TGCT cis rs3858526 0.606 rs10838883 chr11:5952147 G/A cg13902645 chr11:5959945 NA 0.58 6.69 0.51 6.89e-10 DNA methylation (variation); TGCT cis rs425277 0.606 rs3128339 chr1:2046938 G/T cg03732007 chr1:2071316 PRKCZ -0.28 -6.03 -0.48 1.78e-8 Height; TGCT cis rs2836974 0.526 rs1888488 chr21:40686521 C/T cg06238570 chr21:40685208 BRWD1 -0.83 -8.85 -0.62 7.32e-15 Cognitive function; TGCT cis rs6543140 0.964 rs10200081 chr2:103091556 T/C cg09003973 chr2:102972529 NA 0.54 4.46 0.37 1.83e-5 Blood protein levels; TGCT cis rs9640161 0.750 rs59211922 chr7:150023790 T/G cg17279839 chr7:150038598 RARRES2 0.43 4.6 0.38 1.02e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs9467773 0.523 rs2498399 chr6:26706544 T/C cg15659132 chr6:26577336 NA 0.86 9.64 0.65 9.36e-17 Intelligence (multi-trait analysis); TGCT cis rs10789491 1.000 rs1545206 chr1:47185082 C/G cg15501359 chr1:47185051 KIAA0494 0.82 8.36 0.6 1.08e-13 Response to hepatitis C treatment; TGCT cis rs12134245 0.776 rs13447464 chr1:91968278 G/A cg25838465 chr1:92012736 NA -0.44 -7.01 -0.53 1.37e-10 Breast cancer; TGCT cis rs6089584 0.606 rs2144674 chr20:60576579 G/A cg13770153 chr20:60521292 NA -0.41 -4.95 -0.41 2.38e-6 Body mass index; TGCT cis rs9372253 1.000 rs9386894 chr6:110718853 A/G cg19196401 chr6:110721138 DDO -0.52 -7.57 -0.56 7.36e-12 Platelet distribution width; TGCT cis rs7246657 0.722 rs1564208 chr19:38041221 A/G cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs8014204 0.816 rs10144023 chr14:75291531 T/C cg06637938 chr14:75390232 RPS6KL1 0.57 5.07 0.41 1.4e-6 Caffeine consumption; TGCT cis rs780096 0.526 rs1647276 chr2:27688601 C/T cg12000995 chr2:27665139 KRTCAP3 -0.36 -4.45 -0.37 1.9e-5 Total body bone mineral density; TGCT cis rs8103278 1.000 rs9676288 chr19:46292060 G/T cg14061069 chr19:46274453 DMPK -0.43 -6.19 -0.49 8.07e-9 Coronary artery disease; TGCT cis rs4891159 0.757 rs11665018 chr18:74123589 C/T cg24786174 chr18:74118243 ZNF516 -0.61 -9.12 -0.63 1.68e-15 Longevity; TGCT cis rs1426153 0.548 rs12800009 chr11:125159375 A/T cg08311403 chr11:124735215 ROBO3 0.76 4.45 0.37 1.88e-5 Alcohol and nicotine co-dependence; TGCT cis rs12900413 0.631 rs62023455 chr15:90301999 G/A cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs9297145 0.585 rs4729521 chr7:98780520 G/T cg05967295 chr7:98741636 SMURF1 -0.68 -8.35 -0.6 1.12e-13 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs10791097 0.547 rs3829271 chr11:130753912 T/A cg14779329 chr11:130786720 SNX19 0.3 5.08 0.41 1.36e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs7618501 0.966 rs13085679 chr3:49869631 G/A cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.7e-25 Intelligence (multi-trait analysis); TGCT cis rs11792861 0.591 rs7044275 chr9:111717138 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.66 7.62 0.56 5.71e-12 Menarche (age at onset); TGCT cis rs988712 0.672 rs36029218 chr11:27648371 A/T cg10635145 chr11:27742435 BDNF -0.38 -5.23 -0.43 7e-7 Obesity; TGCT cis rs17221829 0.703 rs10047486 chr11:89405190 A/G cg02982614 chr11:89391479 FOLH1B -0.28 -4.67 -0.39 7.81e-6 Anxiety in major depressive disorder; TGCT cis rs4919669 0.668 rs3824756 chr10:104359350 T/C cg05855489 chr10:104503620 C10orf26 0.71 4.69 0.39 7.18e-6 Systolic blood pressure (long-term average);Mean arterial pressure (long-term average); TGCT cis rs72768842 1.000 rs114878198 chr5:78939907 C/A cg24834873 chr5:79865402 ANKRD34B -1.16 -4.61 -0.38 9.84e-6 Post bronchodilator FEV1/FVC ratio in COPD; TGCT trans rs11088226 0.681 rs2833895 chr21:33929802 G/A cg09050820 chr6:167586206 TCP10L2 0.76 6.79 0.52 4.22e-10 Gastritis; TGCT cis rs1215050 0.527 rs1214998 chr4:99042878 T/G cg17366294 chr4:99064904 C4orf37 0.59 6.26 0.49 5.68e-9 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10875746 0.859 rs12305647 chr12:48582961 T/C cg20731937 chr12:48336164 NA 0.59 4.72 0.39 6.13e-6 Longevity (90 years and older); TGCT cis rs9467711 0.790 rs41266839 chr6:26409890 G/C cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT trans rs4332037 0.539 rs57148375 chr7:2025001 G/C cg10840412 chr1:235813424 GNG4 0.93 6.69 0.51 6.97e-10 Bipolar disorder; TGCT cis rs2562456 0.876 rs11085465 chr19:21751790 A/G cg25650185 chr19:21324782 ZNF431 0.66 5.85 0.46 4.18e-8 Pain; TGCT cis rs7100689 0.646 rs7919380 chr10:82133380 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs9291683 0.509 rs998676 chr4:9948564 T/C cg11266682 chr4:10021025 SLC2A9 -0.62 -8.51 -0.61 4.84e-14 Bone mineral density; TGCT cis rs2692947 0.770 rs2579552 chr2:96737083 A/G cg23100626 chr2:96804247 ASTL 0.4 4.75 0.39 5.55e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs950776 0.518 rs4886571 chr15:78833758 G/A cg06917634 chr15:78832804 PSMA4 -0.95 -9.52 -0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs10883723 0.810 rs6584508 chr10:104258567 A/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs3862260 0.509 rs3862262 chr1:120161841 G/T cg11530693 chr1:120165357 ZNF697 0.2 4.59 0.38 1.09e-5 Systemic lupus erythematosus; TGCT cis rs12497850 0.931 rs11920534 chr3:48937761 G/T cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs8077577 0.895 rs735960 chr17:18057301 G/A cg09161412 chr17:18057145 MYO15A -0.69 -5.57 -0.45 1.5e-7 Obesity-related traits; TGCT cis rs8016982 0.662 rs7148100 chr14:81678096 A/G cg01989461 chr14:81687754 GTF2A1 0.61 4.55 0.38 1.26e-5 Schizophrenia; TGCT cis rs11098499 0.874 rs13123591 chr4:120105990 T/G cg09307838 chr4:120376055 NA 0.5 4.64 0.38 8.86e-6 Corneal astigmatism; TGCT cis rs9818758 0.607 rs80170003 chr3:48951640 T/C cg00383909 chr3:49044727 WDR6 1.39 7.14 0.54 6.9e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs9467773 1.000 rs10946835 chr6:26533757 C/T cg15659132 chr6:26577336 NA 0.86 12.21 0.74 5.3e-23 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.519 rs11495376 chr12:38284957 A/C cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.3e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs1005277 0.579 rs2474567 chr10:38382492 C/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.2 -0.59 2.5e-13 Extrinsic epigenetic age acceleration; TGCT cis rs514406 0.825 rs9661082 chr1:53245472 A/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs10504229 0.683 rs10504224 chr8:58143735 A/G cg20607798 chr8:58055168 NA 0.57 4.91 0.4 2.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs3749237 0.595 rs4855877 chr3:49448527 T/C cg02487422 chr3:49467188 NICN1 0.58 5.95 0.47 2.56e-8 Resting heart rate; TGCT cis rs713587 0.713 rs12466350 chr2:25239969 A/G cg01884057 chr2:25150051 NA 0.38 7.82 0.57 1.95e-12 Body mass index in non-asthmatics; TGCT cis rs9660992 0.710 rs1180721 chr1:205232696 T/C cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs13242816 1.000 rs7801950 chr7:116154783 C/T cg16553024 chr7:116138462 CAV2 -0.45 -5.27 -0.43 5.81e-7 P wave duration; TGCT cis rs921968 0.541 rs2556391 chr2:219556346 T/C cg02176678 chr2:219576539 TTLL4 -0.5 -6.95 -0.53 1.8e-10 Mean corpuscular hemoglobin concentration; TGCT trans rs57221529 0.608 rs11749927 chr5:668842 C/T cg11887960 chr12:57824829 NA 1.04 9.03 0.63 2.77e-15 Lung disease severity in cystic fibrosis; TGCT cis rs1801251 1.000 rs1801251 chr2:233633460 G/A cg25237894 chr2:233734115 C2orf82 0.33 5.95 0.47 2.53e-8 Coronary artery disease; TGCT cis rs2688608 0.967 rs9971040 chr10:75661162 G/C cg04320760 chr10:75533139 FUT11 -0.31 -4.84 -0.4 3.72e-6 Inflammatory bowel disease; TGCT cis rs9894429 0.646 rs7210026 chr17:79612382 T/C cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs12579753 0.917 rs11115029 chr12:82202219 C/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs1372520 0.684 rs184810 chr4:90697979 T/C cg15133208 chr4:90757351 SNCA 0.47 5.58 0.45 1.43e-7 Neuroticism; TGCT cis rs6088580 0.634 rs6059835 chr20:33020141 A/G cg08999081 chr20:33150536 PIGU 0.29 5.66 0.45 9.92e-8 Glomerular filtration rate (creatinine); TGCT cis rs910187 0.678 rs6066229 chr20:45815341 A/G cg27589058 chr20:45804311 EYA2 0.34 7.29 0.55 3.14e-11 Migraine; TGCT cis rs769267 0.930 rs1054930 chr19:19648346 G/C cg20644253 chr19:19431407 KIAA0892;SF4 0.66 5.42 0.44 3.01e-7 Tonsillectomy; TGCT cis rs4148883 0.504 rs4147544 chr4:100134514 G/T cg12011299 chr4:100065546 ADH4 -0.32 -4.55 -0.38 1.29e-5 Alcohol dependence; TGCT trans rs4819388 0.751 rs2838533 chr21:45640260 T/C cg17383793 chr5:52405638 MOCS2 -0.72 -6.89 -0.53 2.52e-10 Celiac disease; TGCT cis rs10927875 0.793 rs1763619 chr1:16326935 A/G cg14742211 chr1:16348397 CLCNKA 0.19 4.45 0.37 1.88e-5 Dilated cardiomyopathy; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.43 4.84 0.4 3.75e-6 Lymphocyte counts; TGCT cis rs7010267 0.935 rs4319131 chr8:119947651 A/G cg17171407 chr8:119960777 TNFRSF11B -0.33 -6.2 -0.49 7.72e-9 Total body bone mineral density (age 45-60); TGCT cis rs4665809 0.590 rs6730317 chr2:26419482 C/T cg04944784 chr2:26401820 FAM59B -0.76 -6.37 -0.5 3.34e-9 Gut microbiome composition (summer); TGCT cis rs17125944 0.505 rs28568967 chr14:53223060 A/G cg00686598 chr14:53173677 PSMC6 1.08 6.35 0.5 3.79e-9 Alzheimer's disease (late onset); TGCT cis rs7312933 0.558 rs1796384 chr12:42780568 G/A cg19980929 chr12:42632907 YAF2 -0.4 -5.66 -0.45 1e-7 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs3796352 1.000 rs71301804 chr3:53073314 C/A cg27565382 chr3:53032988 SFMBT1 0.43 4.62 0.38 9.64e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs737008 0.800 rs535998 chr16:11366003 G/C cg00044050 chr16:11439710 C16orf75 -0.59 -4.56 -0.38 1.21e-5 Obesity-related traits; TGCT cis rs7726839 0.540 rs4957083 chr5:659343 T/C cg09021430 chr5:549028 NA -0.45 -6.27 -0.49 5.56e-9 Obesity-related traits; TGCT cis rs7394190 0.748 rs12573448 chr10:75504512 T/G cg07699608 chr10:75541558 CHCHD1 0.77 4.86 0.4 3.44e-6 Incident atrial fibrillation; TGCT cis rs4268898 0.686 rs2042468 chr2:24398446 A/T cg05570707 chr2:24270316 C2orf44 0.49 4.8 0.4 4.54e-6 Asthma; TGCT trans rs1974653 0.631 rs55929151 chr22:20082566 C/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs7582180 0.764 rs11693424 chr2:100925439 G/A cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs10823500 0.748 rs2394668 chr10:71943951 G/A cg04118878 chr10:71993077 PPA1 0.54 4.96 0.41 2.3e-6 Blood protein levels; TGCT cis rs12971120 0.891 rs2278158 chr18:72178300 G/T cg25817165 chr18:72167213 CNDP2 -0.27 -4.65 -0.39 8.37e-6 Refractive error; TGCT cis rs9467773 0.550 rs4712987 chr6:26399615 A/C cg05738196 chr6:26577821 NA -0.49 -5.11 -0.42 1.19e-6 Intelligence (multi-trait analysis); TGCT cis rs7208859 0.673 rs3764421 chr17:29167653 A/C cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs514406 0.505 rs425520 chr1:53179805 C/G cg22166914 chr1:53195759 ZYG11B 0.45 8.14 0.59 3.47e-13 Monocyte count; TGCT cis rs9300255 0.543 rs1260294 chr12:123560289 T/C cg00376283 chr12:123451042 ABCB9 -0.71 -4.78 -0.39 4.9100000000000004e-06 Neutrophil percentage of white cells; TGCT cis rs1990950 0.692 rs6556028 chr5:156860488 T/C cg25387487 chr5:157003181 ADAM19 0.31 4.78 0.39 4.78e-6 Lung function (FEV1/FVC); TGCT cis rs2115630 0.905 rs6496401 chr15:85297793 A/T cg17173187 chr15:85201210 NMB -0.39 -4.76 -0.39 5.4e-6 P wave terminal force; TGCT cis rs6450176 0.556 rs111423662 chr5:53288661 T/C ch.5.1024479R chr5:53302184 ARL15 -0.8 -5.67 -0.45 9.46e-8 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2982552 0.873 rs1999807 chr6:152064199 C/G cg22157087 chr6:152012887 ESR1 0.21 4.93 0.4 2.61e-6 Bone properties (heel); TGCT cis rs2762353 0.845 rs1937130 chr6:25787554 T/A cg03517284 chr6:25882590 NA 0.5 5.13 0.42 1.1e-6 Blood metabolite levels; TGCT cis rs2288884 0.943 rs75722407 chr19:52525242 C/T cg15405931 chr19:52693188 PPP2R1A -0.69 -4.47 -0.37 1.77e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs11096990 0.819 rs4974991 chr4:39194767 T/A ch.4.37949012R chr4:38272617 NA -0.38 -4.74 -0.39 5.67e-6 Cognitive function; TGCT cis rs7811142 1.000 rs2897358 chr7:100088640 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.6 -0.65 1.15e-16 Platelet count; TGCT cis rs13326165 0.709 rs6796333 chr3:52359678 T/C cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7666738 0.830 rs17548431 chr4:98923768 C/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs116103936 chr4:98954531 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs992157 0.835 rs2045434 chr2:219144498 A/G cg00012203 chr2:219082015 ARPC2 -0.79 -7.87 -0.58 1.48e-12 Colorectal cancer; TGCT cis rs35883536 0.587 rs2809799 chr1:101036516 A/G cg06223162 chr1:101003688 GPR88 0.43 8.31 0.6 1.45e-13 Monocyte count; TGCT cis rs7605378 1.000 rs10194076 chr2:200677663 T/C cg23649088 chr2:200775458 C2orf69 0.33 5.61 0.45 1.25e-7 Osteoporosis; TGCT cis rs57920188 0.584 rs12062024 chr1:4089259 A/T cg20703997 chr1:4087676 NA -0.49 -6.2 -0.49 7.57e-9 Interleukin-17 levels; TGCT cis rs9788721 0.836 rs72738718 chr15:78735438 G/C cg18825076 chr15:78729989 IREB2 -0.33 -5.22 -0.42 7.38e-7 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs6815814 0.950 rs11722788 chr4:38810738 C/G cg02016764 chr4:38805732 TLR1 -0.37 -5.98 -0.47 2.2e-8 Breast cancer; TGCT cis rs1005277 0.579 rs2472178 chr10:38384750 T/C cg25427524 chr10:38739819 LOC399744 -0.38 -7.92 -0.58 1.17e-12 Extrinsic epigenetic age acceleration; TGCT cis rs6674176 0.593 rs6675620 chr1:44417630 C/T cg13606994 chr1:44402422 ARTN -0.46 -4.95 -0.41 2.36e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7824557 0.583 rs2263512 chr8:11233419 T/G cg21775007 chr8:11205619 TDH -0.66 -6.81 -0.52 3.79e-10 Retinal vascular caliber; TGCT cis rs6988636 0.710 rs73339626 chr8:124142757 A/G cg27053337 chr8:124217698 FAM83A 0.77 5.55 0.45 1.65e-7 Urinary uromodulin levels; TGCT cis rs4455778 0.538 rs6965822 chr7:49123931 A/G cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs7219014 1 rs7219014 chr17:37624790 A/G cg07936489 chr17:37558343 FBXL20 -0.6 -4.75 -0.39 5.45e-6 Urinary metabolites; TGCT cis rs7772486 0.720 rs6931553 chr6:146112348 T/C cg23711669 chr6:146136114 FBXO30 -0.93 -10.49 -0.69 8.22e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.953 rs67886764 chr8:58187117 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2439831 1.000 rs28666488 chr15:43741090 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs3820928 1.000 rs1835158 chr2:227763993 C/A cg11843606 chr2:227700838 RHBDD1 -0.53 -4.68 -0.39 7.31e-6 Pulmonary function; TGCT cis rs1577917 0.740 rs9353320 chr6:86244848 C/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.54 4.87 0.4 3.29e-6 Response to antipsychotic treatment; TGCT cis rs9788682 0.948 rs34664138 chr15:78831624 T/G cg24631222 chr15:78858424 CHRNA5 0.92 7.57 0.56 7.51e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2032447 0.507 rs199748 chr6:25909045 C/G cg15691649 chr6:25882328 NA -0.47 -5.25 -0.43 6.45e-7 Intelligence (multi-trait analysis); TGCT cis rs11642862 1.000 rs75500538 chr16:30782449 G/A cg02466173 chr16:30829666 NA -0.39 -4.68 -0.39 7.24e-6 Tonsillectomy; TGCT cis rs6684514 1.000 rs10908494 chr1:156263097 A/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs910316 1.000 rs12589815 chr14:75544101 C/T cg23033748 chr14:75592666 NEK9 0.28 4.76 0.39 5.27e-6 Height; TGCT cis rs7666738 0.830 rs2098934 chr4:98992403 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs9403770 chr6:146423334 C/T cg13319975 chr6:146136371 FBXO30 -0.51 -4.48 -0.37 1.69e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs72781680 0.821 rs72796378 chr2:24167385 G/A cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs921968 0.643 rs522377 chr2:219437476 T/C cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs67311347 0.544 rs2278930 chr3:40351092 C/T cg13683864 chr3:40499215 RPL14 -0.81 -7.58 -0.56 7.14e-12 Renal cell carcinoma; TGCT cis rs708547 0.957 rs1718875 chr4:57837438 C/T cg25525207 chr4:57843836 C4orf14;POLR2B -0.57 -4.68 -0.39 7.48e-6 Response to bleomycin (chromatid breaks); TGCT cis rs9300255 0.537 rs1716182 chr12:123686127 A/C cg00376283 chr12:123451042 ABCB9 0.71 5.59 0.45 1.41e-7 Neutrophil percentage of white cells; TGCT cis rs7811142 1.000 rs67315960 chr7:100015124 A/G cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs7584330 0.868 rs7571898 chr2:238383028 T/C cg08992911 chr2:238395768 MLPH 0.64 5.13 0.42 1.07e-6 Prostate cancer; TGCT cis rs514406 0.825 rs6695819 chr1:53223366 T/C cg08859206 chr1:53392774 SCP2 0.4 5.97 0.47 2.38e-8 Monocyte count; TGCT cis rs3820068 0.581 rs72645881 chr1:15928203 C/T cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs6570726 0.846 rs9376954 chr6:145943737 T/A cg23711669 chr6:146136114 FBXO30 0.84 9.16 0.64 1.36e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs6840360 0.967 rs1105534 chr4:152605312 C/A cg17479576 chr4:152424074 FAM160A1 -0.47 -4.86 -0.4 3.41e-6 Intelligence (multi-trait analysis); TGCT cis rs61990749 0.597 rs117131659 chr14:78131126 C/T cg23188588 chr14:78226832 SNW1;C14orf178 -0.68 -4.76 -0.39 5.29e-6 Fibroblast growth factor basic levels; TGCT cis rs7192750 0.586 rs8062946 chr16:71930807 A/G cg06353428 chr16:71660113 MARVELD3 0.83 7.32 0.55 2.74e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7523273 0.925 rs12749612 chr1:208006749 A/G cg22525895 chr1:207977042 MIR29B2 -0.49 -8.69 -0.62 1.78e-14 Schizophrenia; TGCT cis rs5769765 0.773 rs9616383 chr22:50313014 T/C cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs9447004 0.584 rs7747167 chr6:74430673 T/G cg23004174 chr6:74404879 CD109 0.23 5.04 0.41 1.58e-6 Blood protein levels;Calcium levels; TGCT cis rs367615 0.661 rs9326775 chr5:108836925 A/T cg17395555 chr5:108820864 NA 0.31 5.86 0.47 3.94e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs2326825 0.624 rs1938164 chr6:6805059 C/T cg06501113 chr6:6534839 LOC285780 0.35 4.64 0.38 8.69e-6 Gastroesophageal reflux disease; TGCT cis rs12579753 1.000 rs7306395 chr12:82175867 A/G cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs2046867 0.908 rs62251655 chr3:72821708 T/C cg25664220 chr3:72788482 NA -0.55 -6.92 -0.53 2.15e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs2404602 0.669 rs17464903 chr15:77195486 A/G cg22467129 chr15:76604101 ETFA -0.47 -5.33 -0.43 4.47e-7 Blood metabolite levels; TGCT cis rs597539 0.616 rs72945243 chr11:68633358 T/C cg06028808 chr11:68637592 NA 0.51 6.66 0.51 7.87e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2439831 0.867 rs12443102 chr15:43932103 G/C cg27015174 chr15:43622946 ADAL;LCMT2 0.72 4.8 0.4 4.52e-6 Lung cancer in ever smokers; TGCT cis rs950169 0.580 rs62021208 chr15:85196244 G/A cg12863693 chr15:85201151 NMB 0.46 5.51 0.44 1.97e-7 Schizophrenia; TGCT cis rs765787 0.530 rs12915027 chr15:45512626 G/A cg24006582 chr15:45444508 DUOX1 0.25 5.35 0.43 4.11e-7 Uric acid levels; TGCT cis rs7611238 0.538 rs62287119 chr3:195078818 G/A cg27323046 chr3:195102265 ACAP2 0.39 5.09 0.42 1.29e-6 Body mass index; TGCT cis rs2204008 0.805 rs11180825 chr12:38242916 G/T cg13010199 chr12:38710504 ALG10B 0.64 5.01 0.41 1.85e-6 Bladder cancer; TGCT cis rs13108904 0.539 rs13141992 chr4:1340765 C/T cg00684032 chr4:1343700 KIAA1530 0.24 4.91 0.4 2.82e-6 Obesity-related traits; TGCT cis rs12477438 0.748 rs6712773 chr2:99585781 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs7267979 1.000 rs2257809 chr20:25266476 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12134245 0.776 rs12125947 chr1:91990487 T/C cg07090678 chr1:91966139 CDC7 0.34 4.72 0.39 6.29e-6 Breast cancer; TGCT cis rs67311347 1.000 rs73080126 chr3:40509153 A/G cg13683864 chr3:40499215 RPL14 -1.2 -13.3 -0.77 1.27e-25 Renal cell carcinoma; TGCT cis rs4563143 0.663 rs2218396 chr19:29236392 C/T cg14983838 chr19:29218262 NA 0.74 6.69 0.52 6.75e-10 Methadone dose in opioid dependence; TGCT cis rs11148252 0.532 rs9536190 chr13:53181044 T/C cg00495681 chr13:53174319 NA 0.91 10.15 0.67 5.33e-18 Lewy body disease; TGCT cis rs11809207 1.000 rs11247865 chr1:26517773 T/C cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs67311347 0.544 rs13098483 chr3:40342743 G/C cg13683864 chr3:40499215 RPL14 -0.78 -7.5 -0.56 1.06e-11 Renal cell carcinoma; TGCT cis rs9326248 1.000 rs664922 chr11:117070895 C/A cg16524733 chr11:117070046 TAGLN 0.33 4.9 0.4 2.87e-6 Blood protein levels; TGCT cis rs2404618 0.504 rs2906567 chr8:1494118 C/T cg13402656 chr8:1511478 DLGAP2 -0.36 -6.27 -0.49 5.6e-9 Lung cancer; TGCT cis rs7772486 0.790 rs9376971 chr6:146259505 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9868809 0.505 rs11706983 chr3:48738678 A/G cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs6671200 1.000 rs6678964 chr1:95694268 C/T cg26537280 chr1:95699037 RWDD3 0.73 6.19 0.49 8.07e-9 Stearic acid (18:0) levels; TGCT cis rs7226408 0.857 rs4344828 chr18:34613339 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs916888 0.773 rs169201 chr17:44790203 A/G cg15921436 chr17:44337874 NA 0.59 8.18 0.59 2.85e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 0.953 rs75585481 chr8:58192202 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs10832169 0.933 rs11023060 chr11:14064931 T/G cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs7552404 1.000 rs4949875 chr1:76173080 G/A cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg12311346 chr5:56204834 C5orf35 -0.63 -6.36 -0.5 3.5e-9 Initial pursuit acceleration; TGCT cis rs2153535 0.580 rs2327061 chr6:8447231 G/C cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs12579753 0.879 rs11115002 chr12:82153090 C/T cg07988820 chr12:82153109 PPFIA2 -0.66 -7.01 -0.53 1.32e-10 Resting heart rate; TGCT cis rs2836974 0.666 rs11910705 chr21:40685604 C/T cg17971929 chr21:40555470 PSMG1 -0.72 -6.53 -0.51 1.5e-9 Cognitive function; TGCT cis rs1008375 0.932 rs2302391 chr4:17660237 T/C cg16339924 chr4:17578868 LAP3 0.65 5.31 0.43 4.8e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs6089829 0.925 rs6122087 chr20:61664553 T/C cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT trans rs804280 0.509 rs35626932 chr8:11786932 C/A cg15556689 chr8:8085844 FLJ10661 0.77 7.03 0.53 1.22e-10 Myopia (pathological); TGCT cis rs10504229 0.953 rs59034808 chr8:58185337 T/C cg24829409 chr8:58192753 C8orf71 -0.52 -5.02 -0.41 1.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs79839061 0.667 rs13104885 chr4:827368 G/C cg07828340 chr4:882639 GAK 0.4 5.08 0.42 1.34e-6 Intelligence (multi-trait analysis); TGCT cis rs17384381 1.000 rs12123745 chr1:85884772 T/C cg16011679 chr1:85725395 C1orf52 0.8 6.44 0.5 2.39e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg06634786 chr22:41940651 POLR3H -0.86 -8.02 -0.58 6.88e-13 Vitiligo; TGCT cis rs6840360 0.533 rs13121190 chr4:152729072 T/G cg22705602 chr4:152727874 NA 0.37 6.56 0.51 1.3e-9 Intelligence (multi-trait analysis); TGCT cis rs4478037 0.558 rs57502645 chr3:33082174 G/A cg19404215 chr3:33155277 CRTAP 1.09 5.31 0.43 4.86e-7 Major depressive disorder; TGCT cis rs2777491 0.915 rs7178777 chr15:41634588 C/A cg18705301 chr15:41695430 NDUFAF1 -0.74 -10.4 -0.68 1.37e-18 Ulcerative colitis; TGCT cis rs2243480 1.000 rs160648 chr7:65543384 C/A cg18252515 chr7:66147081 NA -1.13 -7.39 -0.55 1.94e-11 Diabetic kidney disease; TGCT cis rs1218582 0.772 rs877343 chr1:154910012 A/G cg09359103 chr1:154839909 KCNN3 -0.62 -11.25 -0.71 1.15e-20 Prostate cancer; TGCT cis rs9536318 0.673 rs1323113 chr13:53509475 A/C cg08567279 chr13:53313529 LECT1 0.48 4.47 0.37 1.75e-5 Airflow obstruction; TGCT cis rs1862618 0.853 rs252898 chr5:56188931 T/C cg24549020 chr5:56110836 MAP3K1 0.72 6.03 0.48 1.73e-8 Initial pursuit acceleration; TGCT cis rs6922617 0.786 rs79915147 chr6:41344947 G/T cg07798131 chr6:41471673 NA 0.98 4.85 0.4 3.6e-6 Alzheimer's disease biomarkers; TGCT cis rs6089829 0.962 rs4586690 chr20:61658595 G/T cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs1205863 0.607 rs10947661 chr6:11934964 A/G cg07106625 chr6:11870215 NA -0.44 -4.64 -0.38 8.88e-6 Disc degeneration (lumbar); TGCT cis rs981844 0.961 rs56288418 chr4:154668228 C/A cg14289246 chr4:154710475 SFRP2 1.01 8.67 0.61 2.02e-14 Response to statins (LDL cholesterol change); TGCT cis rs7618915 0.508 rs13065851 chr3:52644836 T/A cg10802521 chr3:52805072 NEK4 -0.72 -9.1 -0.63 1.91e-15 Bipolar disorder; TGCT cis rs7918232 0.943 rs6482593 chr10:27371437 A/G cg14442939 chr10:27389572 ANKRD26 0.73 5.37 0.43 3.69e-7 Breast cancer; TGCT cis rs644799 0.710 rs56384142 chr11:95502075 G/T cg03916912 chr11:95522834 CEP57;FAM76B 0.81 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs16958440 0.867 rs59217333 chr18:44694844 A/C cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg13695892 chr22:41940480 POLR3H 0.8 8.01 0.58 7.2e-13 Vitiligo; TGCT cis rs1729951 0.575 rs361244 chr3:136697506 C/T cg21827317 chr3:136751795 NA 0.4 5.6 0.45 1.28e-7 Neuroticism; TGCT cis rs61884328 0.733 rs79044335 chr11:47200402 G/C cg13308137 chr11:47528955 CUGBP1 0.38 4.48 0.37 1.65e-5 Total body bone mineral density (age over 60); TGCT trans rs9929218 0.551 rs6499193 chr16:68727069 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 0.57 7.35 0.55 2.33e-11 Colorectal cancer; TGCT trans rs3780486 0.846 rs12554995 chr9:33132044 A/G cg20290983 chr6:43655470 MRPS18A 1.19 14.84 0.8 2.81e-29 IgG glycosylation; TGCT cis rs1775715 0.737 rs2799018 chr10:32202069 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.39e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs13108904 0.901 rs7668661 chr4:1300172 A/G cg00684032 chr4:1343700 KIAA1530 0.25 5.09 0.42 1.31e-6 Obesity-related traits; TGCT cis rs2836974 0.653 rs8130556 chr21:40516872 C/T cg06238570 chr21:40685208 BRWD1 0.71 6.51 0.5 1.71e-9 Cognitive function; TGCT cis rs2997447 0.846 rs3008230 chr1:26401331 A/G cg19633962 chr1:26362018 EXTL1 -0.64 -4.46 -0.37 1.84e-5 QRS complex (12-leadsum); TGCT cis rs7236492 0.572 rs78124041 chr18:77181489 G/A cg15644404 chr18:77186268 NFATC1 -0.43 -4.61 -0.38 9.81e-6 Inflammatory bowel disease;Crohn's disease; TGCT cis rs5769707 0.967 rs739248 chr22:50025205 T/C cg05373962 chr22:49881684 NA -0.31 -6.42 -0.5 2.6e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9296092 0.538 rs76589475 chr6:33519517 G/C cg13560919 chr6:33536144 NA -0.21 -4.75 -0.39 5.5e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs1799949 1.000 rs1973646 chr17:41310495 T/C cg23758822 chr17:41437982 NA 0.72 6.96 0.53 1.76e-10 Menopause (age at onset); TGCT cis rs7615952 0.932 rs13314869 chr3:125644669 G/A cg05084668 chr3:125655381 ALG1L -0.75 -6.07 -0.48 1.41e-8 Blood pressure (smoking interaction); TGCT cis rs7954584 1.000 rs7954584 chr12:122461566 G/A cg21171335 chr12:122356390 WDR66 0.55 5.73 0.46 7.28e-8 Mean corpuscular volume; TGCT cis rs9322193 0.923 rs35967444 chr6:149996724 G/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs2072499 0.695 rs112223391 chr1:156156094 G/A cg24450063 chr1:156163899 SLC25A44 1.09 9.82 0.66 3.53e-17 Testicular germ cell tumor; TGCT cis rs909002 0.849 rs10914458 chr1:32096746 T/C cg11573219 chr1:32083031 HCRTR1 -0.47 -6.08 -0.48 1.37e-8 Intelligence (multi-trait analysis); TGCT cis rs11650494 0.908 rs73324323 chr17:47420054 G/T cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs59197085 0.636 rs58320939 chr7:128462843 T/A cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs1153858 1.000 rs60476496 chr15:45713801 C/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.67 0.45 9.65e-8 Homoarginine levels; TGCT cis rs2762353 0.779 rs1165182 chr6:25837829 A/G cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.14e-6 Blood metabolite levels; TGCT cis rs10782582 0.617 rs1846233 chr1:76159354 C/T cg10523679 chr1:76189770 ACADM -0.69 -7.19 -0.54 5.26e-11 Daytime sleep phenotypes; TGCT cis rs7772486 0.790 rs2265919 chr6:146221753 A/G cg23711669 chr6:146136114 FBXO30 0.89 10.16 0.67 5.28e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs2549003 1.000 rs10214312 chr5:131821866 T/G cg02551604 chr5:131831745 NA -0.9 -12.1 -0.74 9.75e-23 Asthma (sex interaction); TGCT cis rs6840360 0.557 rs1143036 chr4:152329404 A/G cg17479576 chr4:152424074 FAM160A1 -0.55 -5.72 -0.46 7.48e-8 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.580 rs2334958 chr3:49252364 C/T cg18654377 chr3:49208889 KLHDC8B -0.37 -4.91 -0.4 2.78e-6 Menarche (age at onset); TGCT cis rs7666738 0.830 rs1813642 chr4:98852225 G/A cg05340658 chr4:99064831 C4orf37 0.52 6.03 0.48 1.78e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg07636037 chr3:49044803 WDR6 0.85 8.88 0.62 6.21e-15 Menarche (age at onset); TGCT cis rs1862618 0.671 rs906631 chr5:56245803 C/G cg24531977 chr5:56204891 C5orf35 0.69 7.29 0.55 3.25e-11 Initial pursuit acceleration; TGCT cis rs10791097 0.694 rs12361892 chr11:130744490 T/G cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4746818 1.000 rs7909631 chr10:70918676 C/T cg04149295 chr10:70884716 VPS26A 0.79 5.44 0.44 2.79e-7 Left atrial antero-posterior diameter; TGCT cis rs7659604 0.628 rs6838153 chr4:122720999 A/G cg06713675 chr4:122721982 EXOSC9 -0.69 -9.57 -0.65 1.4e-16 Type 2 diabetes; TGCT cis rs2594989 1.000 rs2594967 chr3:11349748 T/G cg00170343 chr3:11313890 ATG7 0.61 4.58 0.38 1.11e-5 Circulating chemerin levels; TGCT cis rs425277 0.585 rs3107143 chr1:2045372 G/C cg24578937 chr1:2090814 PRKCZ -0.23 -5.54 -0.45 1.73e-7 Height; TGCT cis rs7666738 0.830 rs890470 chr4:98923435 A/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10875746 0.669 rs61941006 chr12:48631133 G/A cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT cis rs6951245 1.000 rs118059236 chr7:1073202 A/C cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17345786 0.861 rs74768235 chr3:101142821 T/C cg12386194 chr3:101231763 SENP7 0.65 6.33 0.49 4.1e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs2836950 0.520 rs1980407 chr21:40543961 T/C cg11890956 chr21:40555474 PSMG1 -0.73 -6.98 -0.53 1.59e-10 Menarche (age at onset); TGCT cis rs9372498 0.908 rs4551203 chr6:118693502 G/A cg21191810 chr6:118973309 C6orf204 -0.5 -4.61 -0.38 9.92e-6 Diastolic blood pressure; TGCT cis rs9638182 0.725 rs13244268 chr7:72911843 T/C cg14087351 chr7:73037990 MLXIPL -0.61 -4.81 -0.4 4.34e-6 Triglycerides; TGCT cis rs10504229 0.679 rs11781858 chr8:58038406 C/T cg02725872 chr8:58115012 NA -0.4 -4.87 -0.4 3.34e-6 Developmental language disorder (linguistic errors); TGCT cis rs425277 0.585 rs364677 chr1:2071765 A/G cg03732007 chr1:2071316 PRKCZ -0.27 -6.37 -0.5 3.37e-9 Height; TGCT cis rs1941023 0.584 rs2233252 chr11:60157107 T/G cg08716584 chr11:60157161 MS4A7 -0.35 -5.29 -0.43 5.3e-7 Congenital heart disease (maternal effect); TGCT cis rs9790314 0.502 rs34972965 chr3:160984296 G/A cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Morning vs. evening chronotype; TGCT cis rs911555 0.692 rs7146215 chr14:103915908 A/G cg23461800 chr14:103021989 NA -0.34 -4.5 -0.37 1.57e-5 Intelligence (multi-trait analysis); TGCT cis rs4822044 0.561 rs132781 chr22:42046122 T/G cg17554472 chr22:41940697 POLR3H 0.52 5.37 0.43 3.68e-7 Cannabis dependence symptom count; TGCT cis rs8180040 0.726 rs2305634 chr3:47043538 A/G cg27129171 chr3:47204927 SETD2 -0.73 -9.67 -0.66 8.02e-17 Colorectal cancer; TGCT cis rs13256369 0.851 rs13249700 chr8:8563637 C/T cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs7523050 0.643 rs34096625 chr1:109401101 G/A cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs1044826 0.692 rs176987 chr3:139233001 G/A cg00490450 chr3:139108681 COPB2 -0.51 -4.48 -0.37 1.67e-5 Obesity-related traits; TGCT cis rs9534288 0.797 rs7331069 chr13:46564609 A/T cg15192986 chr13:46630673 CPB2 0.48 6.81 0.52 3.68e-10 Blood protein levels; TGCT cis rs4819052 0.851 rs4819049 chr21:46673086 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.87 7.88 0.58 1.43e-12 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11252926 0.550 rs10904148 chr10:454551 G/T cg13477178 chr10:375248 DIP2C -0.24 -4.46 -0.37 1.82e-5 Psychosis in Alzheimer's disease; TGCT cis rs6964587 1.000 rs2282975 chr7:91761638 A/G cg17063962 chr7:91808500 NA 0.87 9.26 0.64 7.83e-16 Breast cancer; TGCT cis rs933688 1.000 rs9293568 chr5:90737845 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.03 8.74 0.62 1.33e-14 Smoking behavior; TGCT cis rs6490294 0.607 rs2339907 chr12:112418146 C/A cg10833066 chr12:111807467 FAM109A 0.33 5.18 0.42 8.61e-7 Mean platelet volume; TGCT cis rs732765 1.000 rs732765 chr14:75365729 A/G cg06637938 chr14:75390232 RPS6KL1 -0.63 -5.39 -0.44 3.49e-7 Non-small cell lung cancer; TGCT cis rs6951245 1.000 rs78185801 chr7:1096367 G/A cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs319204 0.843 rs319171 chr5:146288806 T/C cg25021259 chr5:146258546 PPP2R2B 0.36 4.46 0.37 1.83e-5 Schizophrenia; TGCT cis rs12477438 0.501 rs11123770 chr2:99825102 A/G cg26064155 chr2:99771622 LIPT1;TSGA10 0.85 9.12 0.63 1.72e-15 Chronic sinus infection; TGCT trans rs4332037 0.539 rs11763750 chr7:2080114 G/A cg10840412 chr1:235813424 GNG4 0.94 6.76 0.52 4.78e-10 Bipolar disorder; TGCT cis rs2688608 0.560 rs10128354 chr10:75470045 T/C cg19442545 chr10:75533431 FUT11 -0.37 -5.87 -0.47 3.64e-8 Inflammatory bowel disease; TGCT cis rs7223966 1.000 rs16947005 chr17:61702989 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.55 -4.75 -0.39 5.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs13326165 0.715 rs11707864 chr3:52392877 G/A cg07884673 chr3:53033167 SFMBT1 0.38 4.65 0.39 8.36e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg03173502 chr6:15505345 JARID2 0.9 5.64 0.45 1.1e-7 Gambling; TGCT cis rs6500602 0.674 rs8051695 chr16:4536621 T/C cg08645402 chr16:4508243 NA 0.2 4.98 0.41 2.09e-6 Schizophrenia; TGCT cis rs2862064 1.000 rs1910053 chr5:156463063 G/A cg12943317 chr5:156479607 HAVCR1 -0.45 -5.29 -0.43 5.36e-7 Platelet count; TGCT cis rs1552244 0.554 rs55847233 chr3:9991101 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.3 -4.63 -0.38 9.17e-6 Alzheimer's disease; TGCT cis rs9425766 0.546 rs6691001 chr1:173819076 T/G cg07177756 chr1:173836307 SNORD75;SNORD78;ZBTB37;SNORD76;GAS5;SNORD77;SNORD44 0.49 4.51 0.38 1.49e-5 Life satisfaction; TGCT cis rs7772486 0.686 rs9403739 chr6:146015357 A/G cg23711669 chr6:146136114 FBXO30 -0.87 -9.84 -0.66 3.1e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs3812831 0.695 rs422149 chr13:114931086 T/G cg08824895 chr13:115047677 UPF3A 0.51 4.98 0.41 2.07e-6 Schizophrenia; TGCT cis rs910316 0.737 rs424120 chr14:75482828 G/T cg08847533 chr14:75593920 NEK9 -0.84 -8.92 -0.63 5.19e-15 Height; TGCT cis rs6831352 0.918 rs2851246 chr4:100046104 A/G cg12011299 chr4:100065546 ADH4 0.4 4.88 0.4 3.26e-6 Alcohol dependence; TGCT cis rs9611565 0.570 rs12159188 chr22:42121125 A/T cg06481639 chr22:41940642 POLR3H 0.63 5.6 0.45 1.28e-7 Vitiligo; TGCT cis rs35851103 0.507 rs6601649 chr8:11857317 A/G cg20542592 chr8:11973495 FAM66D 0.54 5.02 0.41 1.78e-6 Neuroticism; TGCT cis rs7216064 1.000 rs62085992 chr17:65923083 T/A cg12091567 chr17:66097778 LOC651250 -0.81 -6.06 -0.48 1.53e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT trans rs3824451 1.000 rs16914811 chr9:101076627 C/T cg11574975 chr1:112058304 ADORA3 -0.44 -6.91 -0.53 2.3e-10 Schizophrenia; TGCT cis rs1215050 0.704 rs783915 chr4:99023151 C/G cg05340658 chr4:99064831 C4orf37 0.43 5.17 0.42 9.18e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7772486 0.754 rs1415747 chr6:146077249 A/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.58 -0.38 1.1e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6912958 0.712 rs6454641 chr6:88371060 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.52 -4.78 -0.39 4.95e-6 Monocyte percentage of white cells; TGCT cis rs6988636 0.710 rs62521797 chr8:124134321 A/T cg23067535 chr8:124195133 FAM83A -0.41 -4.45 -0.37 1.92e-5 Urinary uromodulin levels; TGCT trans rs941408 0.964 rs1736195 chr19:2786557 C/T cg19676328 chr12:49525230 TUBA1B -0.73 -6.74 -0.52 5.36e-10 Total cholesterol levels; TGCT cis rs5769765 0.913 rs28670284 chr22:50221973 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.38 5.18 0.42 8.71e-7 Schizophrenia; TGCT cis rs10504229 0.683 rs2005392 chr8:58106896 T/C cg02725872 chr8:58115012 NA -0.41 -5.42 -0.44 3.01e-7 Developmental language disorder (linguistic errors); TGCT cis rs6912958 1.000 rs13214153 chr6:88153983 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.64 -6.36 -0.5 3.58e-9 Monocyte percentage of white cells; TGCT trans rs3780486 0.846 rs10813954 chr9:33137596 A/C cg20290983 chr6:43655470 MRPS18A 1.2 14.83 0.8 3.07e-29 IgG glycosylation; TGCT cis rs151997 0.671 rs3991902 chr5:50203749 A/T cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs7726839 0.540 rs56325086 chr5:640728 G/A cg09021430 chr5:549028 NA -0.38 -5.21 -0.42 7.5e-7 Obesity-related traits; TGCT cis rs12497850 0.931 rs6446205 chr3:49035211 C/T cg07636037 chr3:49044803 WDR6 0.99 11.03 0.7 4e-20 Parkinson's disease; TGCT cis rs4319547 0.695 rs11836188 chr12:122865507 T/C cg08088222 chr12:122070432 ORAI1 -0.25 -4.5 -0.37 1.56e-5 Body mass index; TGCT cis rs710216 0.917 rs710223 chr1:43411038 C/G cg03128534 chr1:43423976 SLC2A1 0.65 4.57 0.38 1.16e-5 Red cell distribution width; TGCT cis rs9303401 0.659 rs12150264 chr17:56939927 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs7772486 0.790 rs4435956 chr6:146232403 G/C cg23711669 chr6:146136114 FBXO30 -0.87 -9.9 -0.66 2.24e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs4975709 0.569 rs931509 chr5:1858821 A/T cg15595755 chr5:1867978 NA 0.46 5.21 0.42 7.54e-7 Cardiovascular disease risk factors; TGCT cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg03806693 chr22:41940476 POLR3H 1.14 12.75 0.75 2.57e-24 Vitiligo; TGCT cis rs7086627 0.515 rs10887900 chr10:82210265 A/G cg00277334 chr10:82204260 NA -0.53 -8.34 -0.6 1.21e-13 Post bronchodilator FEV1; TGCT cis rs6988636 0.792 rs62521807 chr8:124163621 T/C cg22384356 chr8:124195192 FAM83A -0.39 -4.57 -0.38 1.19e-5 Urinary uromodulin levels; TGCT cis rs4713118 0.868 rs7756968 chr6:27734954 C/G cg20933634 chr6:27740509 NA 0.34 4.79 0.4 4.67e-6 Parkinson's disease; TGCT cis rs7178572 0.625 rs12904553 chr15:77845959 G/A cg22256960 chr15:77711686 NA -0.79 -9.06 -0.63 2.33e-15 Type 2 diabetes; TGCT cis rs9972944 0.627 rs28845012 chr17:63760891 G/A cg07283582 chr17:63770753 CCDC46 -0.26 -5.25 -0.43 6.32e-7 Total body bone mineral density; TGCT cis rs9549367 0.789 rs9549718 chr13:113909822 A/G cg18105134 chr13:113819100 PROZ -0.34 -5.61 -0.45 1.26e-7 Platelet distribution width; TGCT cis rs881375 1.000 rs1953126 chr9:123640500 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.5 5.63 0.45 1.17e-7 Rheumatoid arthritis; TGCT cis rs1801251 1.000 rs283484 chr2:233646505 A/G cg25237894 chr2:233734115 C2orf82 0.32 5.68 0.45 8.93e-8 Coronary artery disease; TGCT cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs2982552 0.967 rs1999806 chr6:152064355 G/A cg22157087 chr6:152012887 ESR1 0.19 4.62 0.38 9.37e-6 Bone properties (heel); TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg01411255 chr17:61851458 DDX42;CCDC47 -0.77 -7.48 -0.56 1.17e-11 Prudent dietary pattern; TGCT cis rs6684514 1.000 rs11264468 chr1:156274585 C/G cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT trans rs1005277 0.579 rs2472178 chr10:38384750 T/C cg17830980 chr10:43048298 ZNF37B -0.83 -10.65 -0.69 3.3e-19 Extrinsic epigenetic age acceleration; TGCT cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg17971929 chr21:40555470 PSMG1 0.98 9.67 0.66 8.18e-17 Cognitive function; TGCT cis rs35146811 0.695 rs1623264 chr7:99811204 G/C cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs2075371 0.933 rs1421482 chr7:133964383 A/G cg11752832 chr7:134001865 SLC35B4 0.69 6.1 0.48 1.24e-8 Mean platelet volume; TGCT cis rs9357506 0.967 rs75331811 chr6:46309143 T/A cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs7698623 0.850 rs10011586 chr4:88798921 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.78 -0.39 4.95e-6 Cardiovascular disease risk factors; TGCT cis rs3125734 0.571 rs7100401 chr10:64024417 C/G cg19640130 chr10:64028056 RTKN2 -0.4 -5.17 -0.42 9.02e-7 Rheumatoid arthritis; TGCT cis rs4664308 0.935 rs6739867 chr2:160942818 G/A cg03641300 chr2:160917029 PLA2R1 -0.28 -6.83 -0.52 3.44e-10 Idiopathic membranous nephropathy; TGCT cis rs6740322 0.748 rs13432574 chr2:43544328 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.41 -7.0 -0.53 1.42e-10 Coronary artery disease; TGCT cis rs67311347 1.000 rs12638199 chr3:40475285 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs751728 1.000 rs6904991 chr6:33732262 T/G cg13859433 chr6:33739653 LEMD2 -0.39 -7.43 -0.56 1.5e-11 Crohn's disease; TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs13191362 1.000 rs67025553 chr6:163011552 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7267979 0.816 rs6115094 chr20:25210827 A/G cg03522245 chr20:25566470 NINL 0.54 5.34 0.43 4.25e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2842992 0.724 rs2273827 chr6:160211339 C/A cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs1552244 1.000 rs58275763 chr3:10143274 C/T cg00149659 chr3:10157352 C3orf10 0.96 6.1 0.48 1.26e-8 Alzheimer's disease; TGCT cis rs1552244 0.554 rs17050704 chr3:10045734 T/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs6582630 0.555 rs11610015 chr12:38508856 A/G cg13010199 chr12:38710504 ALG10B 0.56 4.55 0.38 1.25e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs5750830 0.594 rs9611169 chr22:39783027 C/T cg02038168 chr22:39784481 NA -0.62 -5.41 -0.44 3.19e-7 Intelligence (multi-trait analysis); TGCT cis rs9814567 1.000 rs7356093 chr3:134238753 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.98 -9.89 -0.66 2.32e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs1908814 0.516 rs13252853 chr8:11792974 T/C cg15556689 chr8:8085844 FLJ10661 0.77 7.37 0.55 2.13e-11 Neuroticism; TGCT cis rs514406 0.505 rs7543239 chr1:53162416 A/G cg01802117 chr1:53393560 SCP2 -0.42 -4.86 -0.4 3.51e-6 Monocyte count; TGCT cis rs2688608 0.592 rs10824031 chr10:75509273 C/T cg23231163 chr10:75533350 FUT11 -0.28 -4.86 -0.4 3.51e-6 Inflammatory bowel disease; TGCT cis rs13108904 0.967 rs62293658 chr4:1276416 T/C cg00684032 chr4:1343700 KIAA1530 -0.22 -4.68 -0.39 7.39e-6 Obesity-related traits; TGCT cis rs2032447 0.933 rs4401650 chr6:26035208 G/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.58 -5.78 -0.46 5.74e-8 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.574 rs9467570 chr6:25699283 C/A cg07061783 chr6:25882402 NA 0.74 7.43 0.55 1.54e-11 Blood metabolite levels; TGCT cis rs931127 0.666 rs7932857 chr11:65457493 A/C cg27068330 chr11:65405492 SIPA1 -0.63 -6.32 -0.49 4.26e-9 Systemic lupus erythematosus; TGCT cis rs514406 0.861 rs2065477 chr1:53250213 C/T cg25767906 chr1:53392781 SCP2 -0.46 -5.19 -0.42 8.49e-7 Monocyte count; TGCT cis rs8179 0.700 rs42040 chr7:92245927 C/T cg15732164 chr7:92237376 CDK6 -0.31 -5.28 -0.43 5.56e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs4665809 0.590 rs1560865 chr2:26452197 C/A cg22920501 chr2:26401640 FAM59B -0.8 -6.34 -0.49 3.84e-9 Gut microbiome composition (summer); TGCT cis rs2072499 0.966 rs2842864 chr1:156159217 G/A cg06970220 chr1:156163860 SLC25A44 0.72 6.3 0.49 4.62e-9 Testicular germ cell tumor; TGCT cis rs7027203 0.576 rs7862149 chr9:96546778 A/G cg14598338 chr9:96623480 NA 0.49 7.16 0.54 6.37e-11 DNA methylation (variation); TGCT cis rs7772486 0.754 rs6570703 chr6:145957052 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.625 rs73178625 chr22:41928320 G/C cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs7666738 0.570 rs10032272 chr4:99095601 T/C cg17366294 chr4:99064904 C4orf37 0.55 5.09 0.42 1.29e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs79387448 0.745 rs17027442 chr2:103164948 A/G cg09003973 chr2:102972529 NA -0.98 -6.02 -0.48 1.86e-8 Gut microbiota (bacterial taxa); TGCT cis rs11098499 0.954 rs10017543 chr4:120321420 G/A cg09307838 chr4:120376055 NA 0.67 6.37 0.5 3.35e-9 Corneal astigmatism; TGCT cis rs4919694 0.667 rs117927731 chr10:105112852 C/A cg04362960 chr10:104952993 NT5C2 0.94 6.28 0.49 5.14e-9 Arsenic metabolism; TGCT cis rs9926296 0.607 rs2079672 chr16:89884917 A/G cg08627397 chr16:89984028 MC1R 0.3 4.79 0.4 4.65e-6 Vitiligo; TGCT cis rs13217239 0.646 rs10946897 chr6:26995251 A/C cg26531700 chr6:26746687 NA 0.68 6.86 0.52 2.83e-10 Schizophrenia; TGCT cis rs6540559 0.673 rs17015218 chr1:209967915 A/G cg21951975 chr1:209979733 IRF6 0.69 5.42 0.44 2.99e-7 Cleft lip with or without cleft palate; TGCT cis rs9549260 1.000 rs9549260 chr13:41254104 G/T cg21288729 chr13:41239152 FOXO1 0.75 6.66 0.51 7.91e-10 Red blood cell count; TGCT cis rs1129187 0.967 rs3805952 chr6:42937126 C/T cg09436375 chr6:42928200 GNMT -0.4 -5.2 -0.42 8.08e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs28595532 0.920 rs115118317 chr4:119736613 C/T cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs12902680 0.739 rs12101647 chr15:46408825 G/C cg13605988 chr15:45421612 DUOX1;DUOXA1 0.32 4.5 0.37 1.56e-5 Neuroticism; TGCT cis rs3774830 0.811 rs2654501 chr4:5432416 T/C cg26943120 chr4:5472116 STK32B -0.21 -4.73 -0.39 6.12e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs933688 1.000 rs12656350 chr5:90751343 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.99 8.32 0.6 1.36e-13 Smoking behavior; TGCT cis rs1784581 1.000 rs1784581 chr6:162401127 A/C cg17173639 chr6:162384350 PARK2 -0.5 -9.18 -0.64 1.19e-15 Itch intensity from mosquito bite; TGCT cis rs4788570 0.584 rs4788548 chr16:71655361 A/G cg06353428 chr16:71660113 MARVELD3 1.44 11.08 0.71 2.91e-20 Intelligence (multi-trait analysis); TGCT cis rs3820068 0.608 rs12091326 chr1:16048005 A/G cg05660106 chr1:15850417 CASP9 0.73 6.71 0.52 6.18e-10 Systolic blood pressure; TGCT cis rs4975709 0.589 rs4975746 chr5:1861069 G/A cg07747251 chr5:1868357 NA 0.38 5.46 0.44 2.45e-7 Cardiovascular disease risk factors; TGCT cis rs8103278 0.507 rs2041975 chr19:46238555 T/C cg11657440 chr19:46296263 DMWD 0.74 7.82 0.57 1.92e-12 Coronary artery disease; TGCT cis rs1838472 0.607 rs1997422 chr3:123980608 A/G cg19008133 chr3:123124015 ADCY5 -0.18 -4.48 -0.37 1.64e-5 Schizophrenia; TGCT cis rs6570726 0.764 rs9386125 chr6:145911677 C/T cg13319975 chr6:146136371 FBXO30 -0.52 -4.68 -0.39 7.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9457247 0.515 rs2757039 chr6:167370353 G/T cg23791538 chr6:167370224 RNASET2 0.64 6.13 0.48 1.07e-8 Crohn's disease; TGCT cis rs7639513 0.767 rs3806661 chr3:12705855 A/G cg23032965 chr3:12705835 RAF1 0.77 8.51 0.61 4.81e-14 Itch intensity from mosquito bite; TGCT cis rs7698623 0.850 rs7678318 chr4:88768888 C/T cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs10191773 0.535 rs11123133 chr2:112965023 G/A cg07905836 chr2:113190072 RGPD8;RGPD5 0.45 4.66 0.39 7.94e-6 Yeast infection; TGCT cis rs1129187 0.755 rs7760250 chr6:42929839 G/A cg21280719 chr6:42927975 GNMT -0.37 -4.54 -0.38 1.33e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9296092 0.517 rs7775914 chr6:33518110 T/C cg13560919 chr6:33536144 NA -0.21 -4.74 -0.39 5.87e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs651907 0.557 rs11924013 chr3:101366698 G/A cg11279151 chr3:101281821 RG9MTD1 -0.34 -7.25 -0.55 3.86e-11 Colorectal cancer; TGCT cis rs2075371 0.829 rs35897155 chr7:134002711 G/A cg11752832 chr7:134001865 SLC35B4 0.74 6.76 0.52 4.72e-10 Mean platelet volume; TGCT cis rs4720575 1.000 rs4507670 chr7:47097526 C/T cg00036614 chr7:47093842 NA -0.21 -5.35 -0.43 4.03e-7 Angiotensin-converting enzyme inhibitor intolerance; TGCT cis rs6882046 0.513 rs618298 chr5:88038390 A/G cg24804195 chr5:87968844 LOC645323 -0.62 -6.17 -0.48 8.88e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs9467711 1.000 rs34569761 chr6:26334306 A/G cg03517284 chr6:25882590 NA -0.87 -4.68 -0.39 7.52e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs9814567 1.000 rs2370642 chr3:134222136 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4455778 0.659 rs10245633 chr7:49036606 A/G cg26309511 chr7:48887640 NA 0.44 5.22 0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs1799949 1.000 rs8176077 chr17:41276348 T/C cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs9911578 1.000 rs1631237 chr17:56734695 A/G cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs910316 1.000 rs876402 chr14:75601862 C/T cg11812906 chr14:75593930 NEK9 -0.73 -7.44 -0.56 1.45e-11 Height; TGCT cis rs9308731 1.000 rs9308731 chr2:111908262 G/A cg04202892 chr2:111875749 ACOXL 0.43 4.6 0.38 1.04e-5 Chronic lymphocytic leukemia; TGCT cis rs8141529 0.732 rs2347447 chr22:29179739 C/A cg02153584 chr22:29168773 CCDC117 0.74 6.25 0.49 5.89e-9 Lymphocyte counts; TGCT cis rs6545883 0.929 rs1186710 chr2:61688727 T/A cg15711740 chr2:61764176 XPO1 -0.54 -4.93 -0.4 2.56e-6 Tuberculosis; TGCT cis rs17767294 0.611 rs66487884 chr6:28202912 C/G cg08851530 chr6:28072375 NA 0.87 5.04 0.41 1.58e-6 Parkinson's disease; TGCT cis rs727505 1.000 rs1541416 chr7:124450345 T/C cg23710748 chr7:124431027 NA -0.26 -4.5 -0.37 1.54e-5 Lewy body disease; TGCT cis rs6735179 0.607 rs10185594 chr2:1746661 G/A cg20311673 chr2:1746207 PXDN 0.3 4.77 0.39 5.09e-6 Response to antipsychotic treatment; TGCT cis rs1030877 0.521 rs2576747 chr2:105978676 A/T cg02079111 chr2:105885981 TGFBRAP1 0.17 5.29 0.43 5.25e-7 Obesity-related traits; TGCT cis rs7666738 0.791 rs1527516 chr4:98967937 A/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.966 rs12509962 chr4:17680292 G/A cg18681998 chr4:17616180 MED28 0.88 10.28 0.68 2.7e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs36051895 0.659 rs12349508 chr9:5184222 T/G cg02405213 chr9:5042618 JAK2 -0.71 -8.93 -0.63 4.79e-15 Pediatric autoimmune diseases; TGCT trans rs1005277 0.579 rs932538 chr10:38381314 T/C cg17830980 chr10:43048298 ZNF37B -0.84 -10.72 -0.69 2.25e-19 Extrinsic epigenetic age acceleration; TGCT cis rs2153535 0.547 rs9505475 chr6:8542890 A/G cg07606381 chr6:8435919 SLC35B3 0.56 5.16 0.42 9.56e-7 Motion sickness; TGCT cis rs6121246 1.000 rs6121246 chr20:30433352 C/T cg13852791 chr20:30311386 BCL2L1 0.76 5.67 0.45 9.7e-8 Mean corpuscular hemoglobin; TGCT cis rs4566357 1.000 rs4566357 chr2:227922015 C/T cg11843606 chr2:227700838 RHBDD1 0.51 4.56 0.38 1.19e-5 Coronary artery disease; TGCT cis rs3749237 0.595 rs6797765 chr3:49423976 A/G cg07636037 chr3:49044803 WDR6 0.64 6.04 0.48 1.63e-8 Resting heart rate; TGCT cis rs2945232 1 rs2945232 chr8:8098038 T/C cg15556689 chr8:8085844 FLJ10661 0.87 8.84 0.62 7.94e-15 Schizophrenia; TGCT cis rs36051895 0.623 rs10283467 chr9:5244356 C/G cg02405213 chr9:5042618 JAK2 0.69 8.13 0.59 3.78e-13 Pediatric autoimmune diseases; TGCT cis rs10540 1.000 rs61876341 chr11:495892 C/G cg03934478 chr11:495069 RNH1 0.35 5.82 0.46 4.66e-8 Body mass index; TGCT cis rs9604529 0.532 rs41291213 chr13:114774991 C/T cg13259177 chr13:114761607 RASA3 -0.29 -5.02 -0.41 1.79e-6 Response to tocilizumab in rheumatoid arthritis; TGCT cis rs28595532 0.920 rs116668854 chr4:119707642 A/G cg14228332 chr4:119757509 SEC24D 1.0 4.69 0.39 7.01e-6 Cannabis dependence symptom count; TGCT cis rs35146811 0.735 rs1727140 chr7:99815399 T/A cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs2820315 1.000 rs2820316 chr1:201811761 C/T cg12730843 chr1:201915899 LMOD1 -0.27 -4.77 -0.39 4.98e-6 Body mass index;Body mass index (joint analysis main effects and physical activity interaction);Coronary artery disease;Body mass index in physically active individuals; TGCT cis rs2997447 0.846 rs2997446 chr1:26388241 C/G cg19633962 chr1:26362018 EXTL1 -0.68 -4.7 -0.39 6.68e-6 QRS complex (12-leadsum); TGCT cis rs3091242 0.933 rs9645452 chr1:25668326 C/T cg00786635 chr1:25594202 NA -0.58 -6.02 -0.48 1.87e-8 Erythrocyte sedimentation rate; TGCT cis rs151997 0.962 rs27256 chr5:50190264 G/C cg06027927 chr5:50259733 NA 0.47 4.83 0.4 4e-6 Callous-unemotional behaviour; TGCT cis rs10876993 0.890 rs4760165 chr12:58063801 C/T cg15848620 chr12:58087721 OS9 -0.75 -6.13 -0.48 1.09e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs17376456 1.000 rs13181660 chr5:93533658 A/G cg25358565 chr5:93447407 FAM172A 0.96 7.95 0.58 1.01e-12 Diabetic retinopathy; TGCT cis rs4665809 0.556 rs10221814 chr2:26442759 C/T cg25036284 chr2:26402008 FAM59B -0.65 -5.18 -0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs1348850 0.914 rs4893957 chr2:178380409 A/G cg22681709 chr2:178499509 PDE11A -0.35 -4.55 -0.38 1.27e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.72 -0.39 6.22e-6 Developmental language disorder (linguistic errors); TGCT cis rs616402 0.527 rs2274985 chr1:10573867 G/A cg17425144 chr1:10567563 PEX14 0.55 8.08 0.59 4.81e-13 Breast size; TGCT cis rs12579753 0.956 rs11115039 chr12:82217338 A/C cg07988820 chr12:82153109 PPFIA2 -0.65 -6.81 -0.52 3.72e-10 Resting heart rate; TGCT cis rs72843506 0.591 rs75925580 chr17:20115013 G/T cg18979559 chr17:20280153 CCDC144C -0.65 -4.89 -0.4 3.07e-6 Schizophrenia; TGCT cis rs13256369 0.901 rs4841015 chr8:8567140 C/G cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs1348850 0.872 rs10165785 chr2:178293295 C/T cg22681709 chr2:178499509 PDE11A -0.38 -4.83 -0.4 3.96e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2153535 0.580 rs6905237 chr6:8471790 A/T cg07606381 chr6:8435919 SLC35B3 0.54 5.07 0.41 1.43e-6 Motion sickness; TGCT cis rs4766566 0.704 rs10849931 chr12:111753808 T/C cg10833066 chr12:111807467 FAM109A 0.37 6.47 0.5 2.01e-9 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs9972944 0.729 rs12939140 chr17:63777249 T/A cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs3008870 1.000 rs2065000 chr1:67468124 G/C cg03991309 chr1:68237761 GNG12 -0.28 -4.69 -0.39 6.98e-6 Lymphocyte percentage of white cells; TGCT cis rs826838 0.935 rs1719855 chr12:39127242 C/T cg26384229 chr12:38710491 ALG10B -0.86 -7.72 -0.57 3.37e-12 Heart rate; TGCT cis rs1018836 0.923 rs7007102 chr8:91629730 T/A cg16814680 chr8:91681699 NA -0.85 -9.28 -0.64 7e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.544 rs8128919 chr21:40711862 C/T cg17971929 chr21:40555470 PSMG1 0.61 5.57 0.45 1.51e-7 Cognitive function; TGCT cis rs3785574 0.962 rs2665799 chr17:61919723 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 5.45 0.44 2.66e-7 Height; TGCT cis rs875971 0.862 rs1968126 chr7:66057004 A/G cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs1552244 1.000 rs7651058 chr3:10066964 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs77216612 0.835 rs56692845 chr12:12887811 C/T cg04607235 chr12:12878440 APOLD1 -0.97 -8.51 -0.61 4.81e-14 Lymphocyte counts; TGCT cis rs13191362 1.000 rs68045643 chr6:163029709 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.65 5.32 0.43 4.7e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9913156 0.793 rs55782417 chr17:4562845 G/A cg23387401 chr17:4582204 PELP1 0.31 4.57 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg10862848 chr6:42927986 GNMT -0.38 -4.7 -0.39 6.7e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7599312 0.534 rs2128321 chr2:213405276 G/T cg20637307 chr2:213403960 ERBB4 0.88 11.47 0.72 3.32e-21 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3733585 0.699 rs28837683 chr4:9959808 C/T cg11266682 chr4:10021025 SLC2A9 -0.57 -7.47 -0.56 1.23e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs59107033 0.559 rs62262395 chr3:123105437 C/A cg04890266 chr3:123102914 ADCY5 -0.49 -7.87 -0.58 1.48e-12 Lymphocyte counts; TGCT cis rs9948 0.655 rs62156212 chr2:97399096 C/T cg01990225 chr2:97406019 LMAN2L -1.02 -5.19 -0.42 8.43e-7 Erectile dysfunction and prostate cancer treatment; TGCT trans rs7726839 0.540 rs72703095 chr5:601789 T/C cg25482853 chr8:67687455 SGK3 1.27 10.56 0.69 5.48e-19 Obesity-related traits; TGCT cis rs7714584 1.000 rs1816256 chr5:150272853 T/C cg22134413 chr5:150180641 NA 0.83 6.27 0.49 5.47e-9 Crohn's disease; TGCT cis rs514406 0.763 rs9988539 chr1:53213884 T/C cg08736216 chr1:53307985 ZYG11A 0.25 4.77 0.39 4.98e-6 Monocyte count; TGCT cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.68e-9 Blood metabolite levels; TGCT trans rs561341 1.000 rs508192 chr17:30315147 C/T cg20587970 chr11:113659929 NA 1.02 12.02 0.73 1.52e-22 Hip circumference adjusted for BMI; TGCT cis rs61990749 0.597 rs176944 chr14:78176211 G/T cg02301378 chr14:78227641 SNW1;C14orf178 -0.63 -4.62 -0.38 9.34e-6 Fibroblast growth factor basic levels; TGCT cis rs7819412 0.595 rs10106914 chr8:10987651 T/G cg21775007 chr8:11205619 TDH -0.55 -5.07 -0.41 1.41e-6 Triglycerides; TGCT cis rs3845702 0.866 rs3914458 chr2:180862606 A/G cg01881094 chr2:180872142 CWC22 -0.68 -6.11 -0.48 1.16e-8 Schizophrenia; TGCT cis rs17767294 0.708 rs115714358 chr6:27964332 A/C cg08851530 chr6:28072375 NA 1.56 7.22 0.54 4.47e-11 Parkinson's disease; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs231513 0.954 rs425135 chr17:41984517 A/C cg26893861 chr17:41843967 DUSP3 -0.73 -5.35 -0.43 4.16e-7 Cognitive function; TGCT cis rs10788264 0.561 rs7916839 chr10:124062223 C/T cg09507567 chr10:124027408 NA 0.38 5.42 0.44 2.99e-7 Total body bone mineral density; TGCT cis rs5750830 0.649 rs5750808 chr22:39790987 G/A cg05872129 chr22:39784769 NA -1.02 -11.22 -0.71 1.32e-20 Intelligence (multi-trait analysis); TGCT cis rs1348850 0.634 rs1534304 chr2:178489264 C/T cg19192590 chr2:178524533 PDE11A 0.51 4.8 0.4 4.54e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs6582630 0.502 rs10880388 chr12:38401341 A/T cg13010199 chr12:38710504 ALG10B 0.59 4.68 0.39 7.35e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs3858526 0.959 rs10838795 chr11:5920721 A/G cg13902645 chr11:5959945 NA 0.42 4.74 0.39 5.76e-6 DNA methylation (variation); TGCT cis rs10992471 0.756 rs3758229 chr9:95078852 G/T cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.23 -0.49 6.69e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10089 1.000 rs2054444 chr5:127493206 A/C cg19767477 chr5:127420684 SLC12A2 0.44 4.63 0.38 9.22e-6 Ileal carcinoids; TGCT cis rs4523957 0.651 rs9895342 chr17:2081647 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg22535103 chr8:58192502 C8orf71 -0.39 -4.62 -0.38 9.61e-6 Developmental language disorder (linguistic errors); TGCT cis rs2657888 0.528 rs12304519 chr12:56874522 C/A cg23002907 chr12:56915593 RBMS2 -0.39 -4.82 -0.4 4.05e-6 Adiponectin levels; TGCT cis rs6500602 0.727 rs8051389 chr16:4570570 C/T cg08645402 chr16:4508243 NA 0.19 5.25 0.43 6.32e-7 Schizophrenia; TGCT cis rs9810089 0.676 rs526574 chr3:136103349 A/G cg12473912 chr3:136751656 NA 0.37 5.17 0.42 8.93e-7 Gestational age at birth (child effect); TGCT cis rs10193935 0.901 rs72800020 chr2:42655615 A/G cg27598129 chr2:42591480 NA -0.39 -5.5 -0.44 2.12e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs4727027 0.866 rs12666477 chr7:148812322 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.6 0.38 1.04e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs910316 1.000 rs8003506 chr14:75586288 A/C cg08847533 chr14:75593920 NEK9 -0.95 -11.03 -0.7 3.86e-20 Height; TGCT cis rs317865 1.000 rs4635814 chr4:16151148 G/A cg04764131 chr4:16228633 TAPT1;FLJ39653 0.72 4.55 0.38 1.24e-5 Kidney disease (early stage) in type 1 diabetes; TGCT cis rs858239 0.508 rs10242104 chr7:23220450 C/T cg05602783 chr7:23145260 KLHL7 -0.7 -5.57 -0.45 1.52e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs4149423 1.000 rs12620050 chr2:108919798 G/A cg06795125 chr2:108905320 SULT1C2 -0.46 -6.92 -0.53 2.11e-10 Lobe size; TGCT cis rs8014204 0.836 rs7154256 chr14:75252587 A/G cg06637938 chr14:75390232 RPS6KL1 0.72 6.91 0.53 2.31e-10 Caffeine consumption; TGCT cis rs1215050 0.740 rs11097580 chr4:98767255 C/A cg05340658 chr4:99064831 C4orf37 0.44 5.51 0.44 2.01e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7246657 0.943 rs10420430 chr19:37894194 C/G cg18154014 chr19:37997991 ZNF793 0.96 6.69 0.52 6.7e-10 Coronary artery calcification; TGCT cis rs4455778 0.629 rs6972830 chr7:49022339 G/A cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs3091242 0.935 rs4233043 chr1:25765483 A/G cg23205692 chr1:25664452 TMEM50A 0.47 4.88 0.4 3.15e-6 Erythrocyte sedimentation rate; TGCT cis rs28386778 0.897 rs2584617 chr17:61925298 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs1420338 0.867 rs7795950 chr7:34161715 A/G cg01275685 chr7:34179230 BMPER -0.26 -4.87 -0.4 3.28e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs8068544 0.818 rs7209012 chr17:40161323 C/T cg18442075 chr17:40169520 DNAJC7;NKIRAS2 -1.08 -5.02 -0.41 1.75e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs4853012 0.941 rs78128123 chr2:74347525 C/T cg05890377 chr2:74357713 NA 0.46 5.35 0.43 4.06e-7 Gestational age at birth (maternal effect); TGCT cis rs9549367 0.636 rs486407 chr13:113833499 G/A cg00898013 chr13:113819073 PROZ 0.55 7.34 0.55 2.43e-11 Platelet distribution width; TGCT cis rs9291683 0.530 rs17246501 chr4:9985710 A/C cg00071950 chr4:10020882 SLC2A9 0.64 8.17 0.59 3.09e-13 Bone mineral density; TGCT cis rs9399135 0.935 rs4273704 chr6:135297520 G/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs11098499 1.000 rs35643470 chr4:120184948 T/C cg24670566 chr4:120433619 PDE5A 0.23 4.58 0.38 1.1e-5 Corneal astigmatism; TGCT trans rs57221529 0.766 rs72703075 chr5:592819 C/T cg25482853 chr8:67687455 SGK3 1.26 10.43 0.68 1.17e-18 Lung disease severity in cystic fibrosis; TGCT cis rs9399135 0.967 rs1041480 chr6:135373076 G/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs9916302 0.851 rs612209 chr17:37442713 G/C cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs1580019 0.563 rs34201720 chr7:32568935 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.95 0.41 2.34e-6 Cognitive ability; TGCT cis rs11098499 0.954 rs13151285 chr4:120314741 C/A cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs6964587 0.967 rs4626516 chr7:91807153 G/C cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.6e-6 Breast cancer; TGCT cis rs425277 1.000 rs381664 chr1:2088104 A/G cg24578937 chr1:2090814 PRKCZ 0.32 8.19 0.59 2.64e-13 Height; TGCT cis rs28386778 0.897 rs2584610 chr17:61934783 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.9e-7 Prudent dietary pattern; TGCT cis rs7267979 0.932 rs6107052 chr20:25530838 G/A cg14121845 chr20:25566513 NINL 0.49 5.36 0.43 3.83e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11112613 0.713 rs12321309 chr12:105943263 T/G cg03607813 chr12:105948248 NA 0.47 5.45 0.44 2.59e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs2274471 0.645 rs3824432 chr9:5091675 G/A cg03390472 chr9:5043263 JAK2 -0.29 -4.63 -0.38 8.95e-6 Crohn's disease; TGCT cis rs931127 0.719 rs11227259 chr11:65459404 T/C cg27068330 chr11:65405492 SIPA1 -0.63 -6.32 -0.49 4.26e-9 Systemic lupus erythematosus; TGCT cis rs10504229 0.953 rs72650891 chr8:58179697 T/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs4654899 0.929 rs7552999 chr1:21314454 T/C cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs1375194 0.606 rs935625 chr2:33811516 C/G cg04131969 chr2:33951647 MYADML -0.58 -5.07 -0.41 1.41e-6 Response to antidepressants in depression; TGCT cis rs61990749 0.544 rs7151211 chr14:78151901 C/A cg23188588 chr14:78226832 SNW1;C14orf178 -0.66 -4.69 -0.39 7.04e-6 Fibroblast growth factor basic levels; TGCT cis rs6940638 0.956 rs3922717 chr6:27030924 A/G cg16898833 chr6:26189333 HIST1H4D 0.71 5.34 0.43 4.2e-7 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.716 rs13108535 chr4:99046324 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6977660 0.714 rs12700077 chr7:19791607 A/G cg07541023 chr7:19748670 TWISTNB -0.8 -4.47 -0.37 1.74e-5 Thyroid stimulating hormone; TGCT cis rs2921036 0.529 rs2979192 chr8:8338147 C/T cg08975724 chr8:8085496 FLJ10661 0.55 4.91 0.4 2.79e-6 Neuroticism; TGCT cis rs2242194 0.816 rs6671688 chr1:154994265 T/C cg06418219 chr1:154948305 SHC1;CKS1B -0.56 -5.18 -0.42 8.76e-7 Schizophrenia; TGCT cis rs3820068 0.705 rs4646092 chr1:15821673 C/T cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT trans rs1005277 0.579 rs116912400 chr10:38479207 G/T cg27523141 chr10:43048294 ZNF37B 0.73 8.51 0.61 4.68e-14 Extrinsic epigenetic age acceleration; TGCT cis rs67478160 0.609 rs6576003 chr14:104291330 C/A cg26031613 chr14:104095156 KLC1 -0.63 -6.35 -0.5 3.78e-9 Schizophrenia; TGCT cis rs2456568 0.548 rs4753113 chr11:93660974 G/A cg17595323 chr11:93583763 C11orf90 -0.42 -5.26 -0.43 6.2e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1059312 0.808 rs900982 chr12:129304369 G/A cg09035930 chr12:129282057 SLC15A4 0.58 10.9 0.7 7.96e-20 Systemic lupus erythematosus; TGCT cis rs10504229 0.724 rs72650827 chr8:58126884 A/T cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT trans rs7819412 0.838 rs3021494 chr8:10983534 A/G cg06636001 chr8:8085503 FLJ10661 -0.75 -7.09 -0.54 9.09e-11 Triglycerides; TGCT cis rs910316 0.810 rs77939209 chr14:75670070 A/G cg08847533 chr14:75593920 NEK9 -0.91 -10.07 -0.67 8.51e-18 Height; TGCT cis rs936229 0.749 rs4886633 chr15:75178207 G/A cg10253484 chr15:75165896 SCAMP2 -0.76 -6.29 -0.49 4.87e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs4851266 1.000 rs999052 chr2:100836106 C/T cg07810366 chr2:100720526 AFF3 -0.39 -5.73 -0.46 7.19e-8 Educational attainment; TGCT cis rs6540559 0.673 rs7511996 chr1:210018473 C/A cg21951975 chr1:209979733 IRF6 0.63 4.76 0.39 5.36e-6 Cleft lip with or without cleft palate; TGCT cis rs7681440 0.647 rs1442136 chr4:90819026 C/T cg10208370 chr4:90758469 SNCA 0.57 5.32 0.43 4.73e-7 Dementia with Lewy bodies; TGCT cis rs13256369 0.708 rs10903310 chr8:8589687 A/C cg17143192 chr8:8559678 CLDN23 -0.58 -4.93 -0.4 2.56e-6 Obesity-related traits; TGCT cis rs66573146 1.000 rs56074877 chr4:6990374 C/T cg05069807 chr4:6945702 TBC1D14 0.31 4.83 0.4 3.91e-6 Granulocyte percentage of myeloid white cells; TGCT trans rs916888 0.821 rs199504 chr17:44861003 C/T cg22968622 chr17:43663579 NA -1.24 -11.01 -0.7 4.49e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7260538 0.808 rs707265 chr19:41524087 A/G cg27089200 chr19:41531976 NA 0.46 5.98 0.47 2.24e-8 DDT metabolite (p,p'-DDE levels); TGCT cis rs67311347 1.000 rs11914297 chr3:40410070 T/C cg13683864 chr3:40499215 RPL14 -1.12 -11.9 -0.73 2.94e-22 Renal cell carcinoma; TGCT trans rs57221529 0.766 rs72706610 chr5:561111 G/A cg25482853 chr8:67687455 SGK3 1.21 10.33 0.68 2.02e-18 Lung disease severity in cystic fibrosis; TGCT cis rs736408 0.677 rs678 chr3:52820981 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.49 -0.37 1.61e-5 Bipolar disorder; TGCT cis rs11249608 0.548 rs6894076 chr5:178449813 T/C cg01312482 chr5:178451176 ZNF879 -0.56 -5.5 -0.44 2.09e-7 Pubertal anthropometrics; TGCT cis rs3125734 0.671 rs3852406 chr10:64015162 T/C cg19640130 chr10:64028056 RTKN2 -0.39 -5.12 -0.42 1.15e-6 Rheumatoid arthritis; TGCT cis rs858239 0.601 rs2068459 chr7:23154313 A/C cg05602783 chr7:23145260 KLHL7 -0.71 -6.11 -0.48 1.2e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs12142240 0.698 rs41294478 chr1:46818442 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1865760 0.566 rs9379821 chr6:26054268 A/C cg17042849 chr6:26104293 HIST1H4C -0.62 -5.41 -0.44 3.18e-7 Height; TGCT cis rs3733585 0.699 rs6449202 chr4:9974043 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.51e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs67478160 0.571 rs1155751 chr14:104286547 C/G cg26031613 chr14:104095156 KLC1 -0.63 -6.37 -0.5 3.33e-9 Schizophrenia; TGCT cis rs9322193 0.924 rs9322189 chr6:149909933 T/C cg13206674 chr6:150067644 NUP43 0.51 4.47 0.37 1.76e-5 Lung cancer; TGCT cis rs4689388 0.890 rs4688991 chr4:6302220 C/G cg14416269 chr4:6271139 WFS1 0.41 5.51 0.44 1.98e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs3774830 0.869 rs11737487 chr4:5446673 G/A cg26943120 chr4:5472116 STK32B 0.22 4.76 0.39 5.33e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg08736216 chr1:53307985 ZYG11A 0.24 4.51 0.38 1.45e-5 Monocyte count; TGCT cis rs1670533 0.932 rs9992925 chr4:1050909 A/T cg20887711 chr4:1340912 KIAA1530 0.7 5.66 0.45 9.77e-8 Recombination rate (females); TGCT cis rs9457247 0.967 rs433191 chr6:167409662 T/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.3e-6 Crohn's disease; TGCT cis rs6665290 0.935 rs6704144 chr1:227201030 C/G cg10327440 chr1:227177885 CDC42BPA -0.95 -17.36 -0.84 5.48e-35 Myeloid white cell count; TGCT cis rs1171582 0.545 rs9943397 chr10:61522319 G/A cg23572703 chr10:62241191 NA -0.27 -4.64 -0.38 8.55e-6 Alopecia areata; TGCT cis rs7463256 0.966 rs6557643 chr8:23097802 A/G cg14349055 chr8:23104193 CHMP7 -1.13 -17.63 -0.85 1.41e-35 Attention deficit hyperactivity disorder; TGCT cis rs4722585 0.533 rs2049843 chr7:26196963 G/A cg07876897 chr7:26191696 NFE2L3 0.4 5.44 0.44 2.75e-7 Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 2 peripheral neuropathy);Response to anti-retroviral therapy (ddI/d4T) in HIV-1 infection (Grade 1 peripheral neuropathy); TGCT cis rs7829975 0.774 rs35431455 chr8:8673736 T/C cg08975724 chr8:8085496 FLJ10661 0.52 4.7 0.39 6.68e-6 Mood instability; TGCT cis rs7772486 0.727 rs12190966 chr6:146146820 T/G cg23711669 chr6:146136114 FBXO30 0.9 10.15 0.67 5.45e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs4654899 0.897 rs1021077 chr1:21106016 A/G cg01072550 chr1:21505969 NA -0.49 -7.89 -0.58 1.37e-12 Superior frontal gyrus grey matter volume; TGCT cis rs514406 0.893 rs6588445 chr1:53424928 T/C cg01802117 chr1:53393560 SCP2 0.4 4.86 0.4 3.44e-6 Monocyte count; TGCT cis rs7698623 0.850 rs6821260 chr4:88787439 T/C cg02735620 chr4:88950514 PKD2 -0.45 -4.79 -0.39 4.73e-6 Cardiovascular disease risk factors; TGCT cis rs2842992 0.830 rs2842974 chr6:160159034 C/T cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs7666738 0.791 rs34088022 chr4:99001508 G/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1055129 0.560 rs9891076 chr17:73911715 C/T cg08125733 chr17:73851984 WBP2 0.57 5.25 0.43 6.4e-7 White matter hyperintensity burden; TGCT cis rs28386778 0.830 rs67905415 chr17:61841236 G/A cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.47 0.56 1.28e-11 Prudent dietary pattern; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs514406 0.929 rs12145105 chr1:53340564 T/C cg16325326 chr1:53192061 ZYG11B 0.59 6.78 0.52 4.32e-10 Monocyte count; TGCT cis rs6879260 1.000 rs888922 chr5:179731635 C/G cg23248424 chr5:179741104 GFPT2 -0.37 -6.97 -0.53 1.69e-10 Height; TGCT cis rs9303401 0.614 rs34941454 chr17:57102742 T/G cg10487724 chr17:56770010 TEX14;RAD51C 0.63 5.82 0.46 4.8e-8 Cognitive test performance; TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg08859206 chr1:53392774 SCP2 -0.42 -6.4 -0.5 2.95e-9 Monocyte count; TGCT cis rs11167764 0.945 rs6878397 chr5:141474012 A/G cg23435118 chr5:141488016 NDFIP1 -0.28 -4.58 -0.38 1.1e-5 Crohn's disease; TGCT cis rs28386778 0.897 rs2584626 chr17:61903179 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs6121246 0.567 rs6120890 chr20:30207659 T/G cg21427119 chr20:30132790 HM13 -0.39 -5.61 -0.45 1.25e-7 Mean corpuscular hemoglobin; TGCT cis rs231513 0.954 rs231516 chr17:41963205 G/A cg26893861 chr17:41843967 DUSP3 -0.71 -5.21 -0.42 7.57e-7 Cognitive function; TGCT cis rs7647973 1.000 rs9871024 chr3:49554241 T/C cg05785598 chr3:49045655 WDR6 -0.38 -4.6 -0.38 1.02e-5 Menarche (age at onset); TGCT cis rs459571 0.920 rs2520094 chr9:136919985 A/T cg14405625 chr9:136855902 VAV2 -0.33 -5.01 -0.41 1.81e-6 Platelet distribution width; TGCT cis rs2456568 0.531 rs7105060 chr11:93661268 C/A cg17595323 chr11:93583763 C11orf90 -0.42 -5.26 -0.43 6.25e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10504229 1.000 rs72650892 chr8:58179714 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.560 rs1889033 chr1:53211887 A/G cg16325326 chr1:53192061 ZYG11B -0.9 -13.21 -0.76 2.07e-25 Monocyte count; TGCT cis rs35306767 0.953 rs11253520 chr10:975961 C/G cg26597838 chr10:835615 NA -0.38 -5.07 -0.41 1.44e-6 Eosinophil percentage of granulocytes; TGCT cis rs2239547 0.522 rs9311485 chr3:52987645 T/G cg10802521 chr3:52805072 NEK4 0.64 6.06 0.48 1.48e-8 Schizophrenia; TGCT cis rs1878931 0.668 rs11643983 chr16:3438865 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.97 11.92 0.73 2.66e-22 Body mass index (adult); TGCT cis rs10479542 0.929 rs10078796 chr5:178978883 T/A cg14820908 chr5:178986412 RUFY1 0.48 4.83 0.4 3.96e-6 Lung cancer; TGCT cis rs1215050 0.605 rs10005628 chr4:98606732 A/T cg05340658 chr4:99064831 C4orf37 0.41 4.84 0.4 3.72e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10501293 0.746 rs7924326 chr11:43031752 A/G cg03447554 chr11:43094025 NA 0.47 6.85 0.52 3.07e-10 Cognitive performance; TGCT cis rs2153535 0.580 rs2327067 chr6:8518482 C/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs4285028 0.948 rs12488334 chr3:121702526 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs7582180 0.652 rs11123830 chr2:100974747 A/G cg14675211 chr2:100938903 LONRF2 0.49 4.65 0.39 8.21e-6 Intelligence (multi-trait analysis); TGCT cis rs597539 0.652 rs496616 chr11:68672800 G/C cg04772025 chr11:68637568 NA 0.6 6.77 0.52 4.48e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9611565 0.918 rs2281333 chr22:41749630 T/C cg03806693 chr22:41940476 POLR3H -1.01 -10.96 -0.7 5.96e-20 Vitiligo; TGCT cis rs7267979 0.714 rs2474763 chr20:25241295 A/G cg03522245 chr20:25566470 NINL 0.48 4.59 0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6424115 0.743 rs2229580 chr1:24201109 C/T cg15997130 chr1:24165203 NA 0.85 9.25 0.64 8.02e-16 Immature fraction of reticulocytes; TGCT cis rs6547741 0.844 rs55826602 chr2:27863452 A/G cg27432699 chr2:27873401 GPN1 -0.24 -6.05 -0.48 1.57e-8 Oral cavity cancer; TGCT cis rs9733 0.596 rs72702580 chr1:150691285 A/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs2354432 1.000 rs2354432 chr1:146693229 C/T cg25205988 chr1:146714368 CHD1L 1.33 8.46 0.6 6.33e-14 Mitochondrial DNA levels; TGCT cis rs13022357 1.000 rs12692544 chr2:160082354 C/T cg00168785 chr2:160142643 WDSUB1 0.46 4.6 0.38 1.04e-5 Sudden cardiac arrest; TGCT cis rs4972806 0.776 rs2072589 chr2:177042871 C/T cg03152288 chr2:177042942 NA 0.66 5.75 0.46 6.5e-8 IgG glycosylation; TGCT cis rs208520 1.000 rs12212063 chr6:66985148 C/A cg07460842 chr6:66804631 NA 0.75 6.49 0.5 1.86e-9 Exhaled nitric oxide output; TGCT cis rs7829975 0.714 rs59046059 chr8:8670736 C/A cg15556689 chr8:8085844 FLJ10661 0.65 5.71 0.46 7.85e-8 Mood instability; TGCT cis rs9346649 0.616 rs1873337 chr6:168492160 T/G cg02770688 chr6:168491649 NA 0.34 6.06 0.48 1.48e-8 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs2204008 0.583 rs12820907 chr12:37990931 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.77 0.57 2.56e-12 Bladder cancer; TGCT cis rs10131894 0.575 rs8006147 chr14:75430033 G/A cg08847533 chr14:75593920 NEK9 0.64 5.88 0.47 3.49e-8 Coronary artery disease; TGCT cis rs6754311 0.551 rs313526 chr2:136445526 C/T cg07169764 chr2:136633963 MCM6 0.69 6.28 0.49 5.13e-9 Mosquito bite size; TGCT cis rs10256972 0.527 rs28671326 chr7:1174973 G/A cg03188948 chr7:1209495 NA 0.45 5.83 0.46 4.45e-8 Longevity;Endometriosis; TGCT cis rs1552244 0.572 rs7645667 chr3:10157337 C/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -5.81 -0.46 4.9e-8 Alzheimer's disease; TGCT cis rs12497850 1.000 rs4858828 chr3:48724811 C/T cg18654377 chr3:49208889 KLHDC8B -0.44 -6.06 -0.48 1.52e-8 Parkinson's disease; TGCT cis rs8033133 0.602 rs12439159 chr15:25323874 T/C cg05951178 chr15:25328739 SNORD116-17;SNORD116-19 -0.24 -4.82 -0.4 4.2e-6 Blood osmolality (transformed sodium); TGCT cis rs1552244 1.000 rs12152512 chr3:10143770 C/T cg00149659 chr3:10157352 C3orf10 0.91 5.89 0.47 3.32e-8 Alzheimer's disease; TGCT cis rs951366 0.789 rs823110 chr1:205701078 G/C cg24503407 chr1:205819492 PM20D1 0.58 8.13 0.59 3.84e-13 Menarche (age at onset); TGCT cis rs1008375 0.966 rs11733730 chr4:17625209 G/C cg18681998 chr4:17616180 MED28 1.08 12.13 0.74 8.24e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9443645 0.869 rs9443621 chr6:79576499 A/G cg09184832 chr6:79620586 NA -0.48 -5.17 -0.42 9.23e-7 Intelligence (multi-trait analysis); TGCT cis rs151997 0.962 rs27612 chr5:50179120 G/A cg06027927 chr5:50259733 NA 0.46 4.61 0.38 9.69e-6 Callous-unemotional behaviour; TGCT cis rs6938 0.514 rs56338926 chr15:75259335 C/A cg10253484 chr15:75165896 SCAMP2 -0.58 -5.21 -0.42 7.66e-7 Breast cancer; TGCT cis rs1153858 1.000 rs60476496 chr15:45713801 C/T cg26924012 chr15:45694286 SPATA5L1 1.1 15.34 0.81 2.01e-30 Homoarginine levels; TGCT cis rs2251381 0.778 rs2245021 chr21:30546841 C/T cg24692254 chr21:30365293 RNF160 0.74 7.43 0.56 1.52e-11 Selective IgA deficiency; TGCT cis rs2456568 0.543 rs4144616 chr11:93621900 A/G cg17595323 chr11:93583763 C11orf90 -0.48 -6.48 -0.5 1.98e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2274273 0.745 rs748017 chr14:55542300 A/G cg01923255 chr14:55878535 KIAA0831 0.56 4.57 0.38 1.15e-5 Protein biomarker; TGCT cis rs2859741 0.967 rs592520 chr1:37513503 G/C cg09363841 chr1:37513479 NA -0.21 -4.91 -0.4 2.77e-6 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs6688613 1.000 rs17551703 chr1:166957879 T/C cg07049167 chr1:166818506 POGK 0.21 4.52 0.38 1.43e-5 Refractive astigmatism; TGCT cis rs35306767 0.903 rs12764024 chr10:922861 A/G cg26597838 chr10:835615 NA 0.74 10.2 0.68 4.21e-18 Eosinophil percentage of granulocytes; TGCT cis rs1218582 0.741 rs705094 chr1:154917314 G/A cg09359103 chr1:154839909 KCNN3 -0.64 -11.84 -0.73 4.25e-22 Prostate cancer; TGCT cis rs826838 0.586 rs10785554 chr12:38628749 T/A cg26384229 chr12:38710491 ALG10B 0.55 5.0 0.41 1.93e-6 Heart rate; TGCT cis rs2760061 0.819 rs708112 chr1:228192452 G/A cg02753203 chr1:228287806 NA 0.3 5.71 0.46 7.95e-8 Diastolic blood pressure; TGCT cis rs12220238 0.915 rs10824074 chr10:75876457 T/A cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.94 0.58 1.02e-12 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs5769765 0.862 rs56377703 chr22:50306940 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.22 -12.72 -0.75 3.08e-24 Schizophrenia; TGCT trans rs1814175 0.817 rs1996982 chr11:49972619 G/T cg03929089 chr4:120376271 NA -0.72 -8.53 -0.61 4.24e-14 Height; TGCT cis rs35306767 0.903 rs12250936 chr10:870109 C/T cg20503657 chr10:835505 NA 0.7 9.83 0.66 3.22e-17 Eosinophil percentage of granulocytes; TGCT cis rs682748 1.000 rs167213 chr5:17160112 A/G cg23987134 chr5:17158319 LOC285696 0.23 5.35 0.43 4.18e-7 Hippocampal atrophy; TGCT cis rs2404602 0.692 rs1471780 chr15:77026526 T/C cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.2e-6 Blood metabolite levels; TGCT cis rs6724607 1.000 rs10165399 chr2:191441595 A/G cg10560079 chr2:191398806 TMEM194B 0.37 5.33 0.43 4.5e-7 Pulse pressure; TGCT cis rs858239 0.541 rs4624924 chr7:23168843 A/C cg05602783 chr7:23145260 KLHL7 -0.65 -5.48 -0.44 2.32e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs10089 1.000 rs1842006 chr5:127508687 G/A cg19767477 chr5:127420684 SLC12A2 -0.44 -4.56 -0.38 1.2e-5 Ileal carcinoids; TGCT cis rs6570726 0.935 rs377130 chr6:145836632 C/T cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs208520 1.000 rs208529 chr6:66957549 T/C cg07460842 chr6:66804631 NA -0.82 -7.44 -0.56 1.46e-11 Exhaled nitric oxide output; TGCT cis rs4891159 0.584 rs690397 chr18:74117767 C/T cg24786174 chr18:74118243 ZNF516 0.71 15.66 0.82 3.6e-31 Longevity; TGCT cis rs2549003 1.000 rs9282762 chr5:131822055 T/C cg21138405 chr5:131827807 IRF1 0.19 4.79 0.39 4.76e-6 Asthma (sex interaction); TGCT cis rs2455799 0.586 rs2121736 chr3:15877165 A/G cg12172478 chr3:16357591 RFTN1 -0.3 -4.49 -0.37 1.62e-5 Mean platelet volume; TGCT cis rs10540 1.000 rs67912009 chr11:495057 G/T cg03934478 chr11:495069 RNH1 0.33 5.42 0.44 2.93e-7 Body mass index; TGCT cis rs1799949 1.000 rs8176083 chr17:41275151 G/C cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs12681288 0.782 rs2123055 chr8:1029500 T/G cg04851639 chr8:1020857 NA -0.35 -6.24 -0.49 6.21e-9 Schizophrenia; TGCT cis rs78487399 0.908 rs60868396 chr2:43836877 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.67 4.95 0.41 2.37e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs910316 0.904 rs7156089 chr14:75645527 A/G cg11812906 chr14:75593930 NEK9 -0.74 -7.3 -0.55 3.1e-11 Height; TGCT cis rs3754214 0.823 rs494041 chr1:150270026 T/C cg09579323 chr1:150459698 TARS2 -0.5 -4.52 -0.38 1.43e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs1023500 0.573 rs133374 chr22:42465941 G/A cg15557168 chr22:42548783 NA -0.22 -5.54 -0.45 1.76e-7 Schizophrenia; TGCT cis rs12602901 0.528 rs12941688 chr17:4985515 G/A cg20814095 chr17:4802981 CHRNE;C17orf107 -0.53 -4.57 -0.38 1.15e-5 Blood metabolite levels; TGCT cis rs9611519 0.732 rs1883826 chr22:41703428 G/A cg03806693 chr22:41940476 POLR3H -0.81 -7.85 -0.58 1.69e-12 Neuroticism; TGCT cis rs7248779 0.512 rs12610522 chr19:2413228 C/T cg22729335 chr19:2427816 TIMM13 1.13 13.77 0.78 9.49e-27 Cortisol levels (saliva); TGCT cis rs314370 0.904 rs314373 chr7:100456595 G/A cg10426581 chr7:100472382 SRRT 0.98 10.52 0.69 7e-19 Resting heart rate; TGCT cis rs7944584 0.632 rs7116451 chr11:47322327 G/A cg20307385 chr11:47447363 PSMC3 0.79 7.81 0.57 2.08e-12 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs4660261 0.561 rs11210934 chr1:44369435 G/A cg12908607 chr1:44402522 ARTN -0.69 -8.61 -0.61 2.71e-14 Intelligence (multi-trait analysis); TGCT cis rs11690935 0.959 rs7586207 chr2:172671094 A/G cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.75 -0.75 2.7e-24 Schizophrenia; TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs7923452 0.938 rs753173 chr10:30778738 T/C cg18806716 chr10:30721971 MAP3K8 0.69 6.19 0.49 7.91e-9 Itch intensity from mosquito bite; TGCT cis rs6860806 0.507 rs270601 chr5:131656997 T/C cg24060327 chr5:131705240 SLC22A5 -0.74 -7.91 -0.58 1.2e-12 Breast cancer; TGCT cis rs6748734 0.948 rs4471886 chr2:241838622 T/C cg04034577 chr2:241836375 C2orf54 -0.41 -6.31 -0.49 4.55e-9 Urinary metabolites; TGCT cis rs8180040 0.966 rs9683033 chr3:47489820 C/T cg27129171 chr3:47204927 SETD2 0.66 8.01 0.58 7.07e-13 Colorectal cancer; TGCT cis rs7937682 0.681 rs7107378 chr11:111401840 C/A cg09085632 chr11:111637200 PPP2R1B 0.52 4.7 0.39 6.67e-6 Primary sclerosing cholangitis; TGCT cis rs727479 0.543 rs6493489 chr15:51514203 C/T cg19946085 chr15:51559439 CYP19A1 -0.31 -4.55 -0.38 1.27e-5 Estradiol levels; TGCT cis rs12477438 0.798 rs13412764 chr2:99583733 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.68 -5.97 -0.47 2.3e-8 Chronic sinus infection; TGCT cis rs1552244 0.882 rs3732967 chr3:10015437 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs1008375 1.000 rs10011865 chr4:17645710 G/A cg10189774 chr4:17578691 LAP3 0.57 5.15 0.42 9.95e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11122272 0.735 rs1076804 chr1:231498460 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.68 -0.51 7.25e-10 Hemoglobin concentration; TGCT cis rs2288884 1.000 rs76768215 chr19:52572623 C/T cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs7523050 0.643 rs34920128 chr1:109400889 C/T cg08274380 chr1:109419600 GPSM2 1.3 6.39 0.5 2.99e-9 Fat distribution (HIV); TGCT cis rs10927875 0.722 rs6660685 chr1:16346988 A/G cg21385522 chr1:16154831 NA 0.62 6.41 0.5 2.76e-9 Dilated cardiomyopathy; TGCT cis rs11711311 1.000 rs16861312 chr3:113492402 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs62103177 0.525 rs8086024 chr18:77746623 A/G cg07235805 chr18:78004237 PARD6G -0.48 -4.89 -0.4 3e-6 Opioid sensitivity; TGCT cis rs2762353 0.718 rs1747550 chr6:25851533 A/G cg15691649 chr6:25882328 NA -0.38 -4.95 -0.41 2.35e-6 Blood metabolite levels; TGCT cis rs1949733 1.000 rs868105 chr4:8501030 G/T cg13073564 chr4:8508604 NA 0.47 5.05 0.41 1.55e-6 Response to antineoplastic agents; TGCT cis rs13256369 0.789 rs13282500 chr8:8568489 A/T cg17143192 chr8:8559678 CLDN23 0.57 5.3 0.43 5.05e-7 Obesity-related traits; TGCT cis rs514406 0.893 rs1242317 chr1:53414766 T/C cg24675658 chr1:53192096 ZYG11B -0.69 -8.05 -0.59 5.8e-13 Monocyte count; TGCT cis rs10751667 0.666 rs4074231 chr11:978219 G/C cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs769267 0.929 rs2965180 chr19:19491973 T/C cg08509172 chr19:19383838 TM6SF2 0.35 4.63 0.38 9.18e-6 Tonsillectomy; TGCT cis rs7959452 0.719 rs57954211 chr12:69748397 C/A cg20891283 chr12:69753455 YEATS4 0.83 8.77 0.62 1.16e-14 Blood protein levels; TGCT cis rs9928842 0.712 rs8057843 chr16:75221555 T/G cg09066997 chr16:75300724 BCAR1 0.26 4.65 0.39 8.39e-6 Alcoholic chronic pancreatitis; TGCT cis rs6840360 0.642 rs2724580 chr4:152372505 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs2832191 0.967 rs1999321 chr21:30530233 A/C cg08807101 chr21:30365312 RNF160 0.52 4.71 0.39 6.57e-6 Dental caries; TGCT cis rs7089973 0.604 rs7923693 chr10:116619566 A/G cg03647239 chr10:116582469 FAM160B1 0.59 5.61 0.45 1.26e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7666738 0.791 rs6851549 chr4:99029827 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs933688 1.000 rs10059163 chr5:90742444 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.09 9.69 0.66 7.22e-17 Smoking behavior; TGCT cis rs28386778 0.897 rs1062787 chr17:61896004 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs9911578 1.000 rs2333332 chr17:56631054 A/G cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg10819733 chr22:24237672 NA 0.28 4.59 0.38 1.09e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs62103177 0.673 rs4438371 chr18:77615988 C/T cg12964065 chr18:77638022 KCNG2 0.31 4.46 0.37 1.84e-5 Opioid sensitivity; TGCT cis rs6089584 0.893 rs6089305 chr20:60571817 T/C cg16423285 chr20:60520624 NA -0.62 -6.87 -0.53 2.75e-10 Body mass index; TGCT cis rs55692468 0.652 rs10173398 chr2:153354994 G/A cg10068330 chr2:152622650 NA -0.32 -4.46 -0.37 1.85e-5 Intraocular pressure; TGCT cis rs3845702 0.736 rs2678936 chr2:180872179 G/C cg01881094 chr2:180872142 CWC22 1.07 6.79 0.52 4.2e-10 Schizophrenia; TGCT cis rs5750830 0.649 rs5750820 chr22:39825322 T/G cg02038168 chr22:39784481 NA -0.79 -6.79 -0.52 4.07e-10 Intelligence (multi-trait analysis); TGCT cis rs1005277 0.540 rs11011351 chr10:38030525 A/G cg25427524 chr10:38739819 LOC399744 -0.33 -6.6 -0.51 1.07e-9 Extrinsic epigenetic age acceleration; TGCT cis rs3862030 0.839 rs7078511 chr10:104283874 C/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.53 -5.15 -0.42 9.99e-7 Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for body mass index; TGCT cis rs910316 0.763 rs175014 chr14:75456927 A/G cg11812906 chr14:75593930 NEK9 -0.61 -5.66 -0.45 9.82e-8 Height; TGCT trans rs17685 0.753 rs2286830 chr7:75693963 C/T cg19862616 chr7:65841803 NCRNA00174 -0.53 -9.09 -0.63 2.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg02018176 chr4:1364513 KIAA1530 0.3 4.86 0.4 3.52e-6 Longevity; TGCT cis rs7647973 1.000 rs2140270 chr3:49439440 A/G cg07636037 chr3:49044803 WDR6 -0.72 -5.79 -0.46 5.35e-8 Menarche (age at onset); TGCT cis rs7618915 0.547 rs62253703 chr3:52632357 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs7666738 0.830 rs9998803 chr4:99002519 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT trans rs7618501 1.000 rs60205400 chr3:49800272 C/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT trans rs1814175 0.817 rs11040651 chr11:49938395 G/A cg03929089 chr4:120376271 NA -0.71 -8.09 -0.59 4.74e-13 Height; TGCT cis rs7100689 0.646 rs2095994 chr10:82127956 G/A cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs9486719 0.857 rs2971606 chr6:97043025 C/G cg18709589 chr6:96969512 KIAA0776 -0.78 -6.38 -0.5 3.24e-9 Migraine;Coronary artery disease; TGCT cis rs2677744 0.626 rs867468 chr15:91498127 G/A cg23684204 chr15:91497937 RCCD1 0.39 5.92 0.47 2.91e-8 Attention deficit hyperactivity disorder; TGCT cis rs2070488 0.699 rs13064938 chr3:38440237 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.81 7.71 0.57 3.52e-12 Electrocardiographic conduction measures; TGCT cis rs7811142 1.000 rs2406255 chr7:100053690 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.11 9.52 0.65 1.86e-16 Platelet count; TGCT cis rs10479542 1.000 rs10479542 chr5:178981241 T/A cg21226059 chr5:178986404 RUFY1 0.46 5.02 0.41 1.77e-6 Lung cancer; TGCT cis rs9733 0.593 rs10888384 chr1:150574256 C/T cg13175981 chr1:150552382 MCL1 0.55 6.33 0.49 4.15e-9 Tonsillectomy; TGCT cis rs73001065 0.818 rs12610191 chr19:19721976 C/T cg03709012 chr19:19516395 GATAD2A 1.04 5.1 0.42 1.26e-6 LDL cholesterol; TGCT cis rs8180040 0.932 rs62246474 chr3:47398130 C/T cg27129171 chr3:47204927 SETD2 -0.7 -8.63 -0.61 2.53e-14 Colorectal cancer; TGCT cis rs1008375 1.000 rs62295634 chr4:17685346 C/A cg18681998 chr4:17616180 MED28 0.92 10.35 0.68 1.82e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11190604 1.000 rs11190556 chr10:102209223 G/A cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.639 rs67002486 chr8:58117218 A/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs1729951 0.575 rs361248 chr3:136709066 G/A cg12473912 chr3:136751656 NA 0.39 6.18 0.48 8.68e-9 Neuroticism; TGCT cis rs1218582 0.772 rs6686873 chr1:154913404 C/G cg06221963 chr1:154839813 KCNN3 -0.71 -11.67 -0.72 1.1e-21 Prostate cancer; TGCT cis rs9660992 0.573 rs7531256 chr1:205191202 T/G cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs2657888 0.931 rs2939312 chr12:56932554 G/A cg23932658 chr12:57637574 STAC3 0.48 4.62 0.38 9.53e-6 Adiponectin levels; TGCT cis rs9430161 0.644 rs6685766 chr1:11037051 T/C cg27631724 chr1:11040367 C1orf127 0.54 6.28 0.49 5.3300000000000004e-09 Ewing sarcoma; TGCT cis rs2580764 0.678 rs2580765 chr2:55204028 A/C cg09592903 chr2:55203963 RTN4 0.24 5.47 0.44 2.4e-7 Mean platelet volume; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg06873352 chr17:61820015 STRADA 0.56 6.11 0.48 1.19e-8 Prudent dietary pattern; TGCT cis rs9972944 0.902 rs10512504 chr17:63772091 C/T cg07283582 chr17:63770753 CCDC46 0.27 5.27 0.43 5.91e-7 Total body bone mineral density; TGCT cis rs12971120 0.783 rs7229256 chr18:72169129 T/A cg25817165 chr18:72167213 CNDP2 -0.3 -5.61 -0.45 1.28e-7 Refractive error; TGCT cis rs2346177 0.875 rs4413204 chr2:46647092 C/G cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.77 -0.39 5.07e-6 HDL cholesterol; TGCT cis rs9549367 0.713 rs3024756 chr13:113822950 G/C cg00898013 chr13:113819073 PROZ -0.55 -6.92 -0.53 2.14e-10 Platelet distribution width; TGCT cis rs11031096 0.502 rs7935824 chr11:4046900 C/G cg18678763 chr11:4115507 RRM1 -0.5 -6.2 -0.49 7.56e-9 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9653442 0.900 rs4851269 chr2:100830348 C/T cg07810366 chr2:100720526 AFF3 0.4 6.01 0.48 1.9e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs9457247 0.967 rs376097 chr6:167410878 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs7666738 0.830 rs4392515 chr4:98957431 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 0.775 rs55825382 chr8:58157605 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -4.81 -0.4 4.27e-6 Developmental language disorder (linguistic errors); TGCT cis rs208520 0.661 rs6937856 chr6:66867468 A/G cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs4911259 0.552 rs62208880 chr20:31463284 T/C cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs2456568 0.771 rs8181530 chr11:93638678 G/A cg17595323 chr11:93583763 C11orf90 -0.47 -6.52 -0.51 1.58e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2046867 0.818 rs1502758 chr3:72865126 A/G cg25664220 chr3:72788482 NA -0.56 -7.04 -0.53 1.16e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs523522 0.673 rs643372 chr12:121022640 C/G cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs10504229 1.000 rs58371676 chr8:58189382 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs3096299 0.933 rs2965823 chr16:89454924 G/A cg06640241 chr16:89574553 SPG7 0.66 6.49 0.5 1.86e-9 Multiple myeloma (IgH translocation); TGCT cis rs7412746 0.658 rs11204723 chr1:150731618 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.63 0.38 9.12e-6 Melanoma; TGCT cis rs13326165 0.760 rs57441156 chr3:52354242 C/G cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7584330 0.737 rs11886117 chr2:238361650 A/T cg14458575 chr2:238380390 NA 0.48 7.57 0.56 7.54e-12 Prostate cancer; TGCT cis rs77861329 1.000 rs171294 chr3:52203599 C/G cg08692210 chr3:52188851 WDR51A 0.93 4.79 0.4 4.61e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs9611565 0.694 rs106860 chr22:41840407 C/T cg13695892 chr22:41940480 POLR3H -0.92 -9.06 -0.63 2.36e-15 Vitiligo; TGCT cis rs11997175 0.574 rs4520125 chr8:33648628 C/T ch.8.33884649F chr8:33765107 NA 0.28 4.53 0.38 1.35e-5 Body mass index; TGCT cis rs35306767 0.951 rs11253530 chr10:993729 T/C cg26597838 chr10:835615 NA 0.62 8.25 0.6 1.94e-13 Eosinophil percentage of granulocytes; TGCT cis rs4654899 0.758 rs17453044 chr1:21517361 A/G cg01072550 chr1:21505969 NA -0.57 -9.6 -0.65 1.15e-16 Superior frontal gyrus grey matter volume; TGCT cis rs13191362 0.507 rs2849524 chr6:163127070 C/T cg21926612 chr6:163149169 PACRG;PARK2 -0.6 -5.61 -0.45 1.23e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs12950390 0.814 rs11659069 chr17:45834275 G/T cg24803719 chr17:45855879 NA -0.47 -4.75 -0.39 5.6e-6 IgG glycosylation; TGCT cis rs7843479 0.601 rs4422769 chr8:21844265 A/G cg17168535 chr8:21777572 XPO7 0.8 8.02 0.58 6.82e-13 Mean corpuscular volume; TGCT cis rs6933660 0.720 rs6913515 chr6:151753470 G/C cg14262678 chr6:151773367 RMND1;C6orf211 0.49 4.56 0.38 1.2e-5 Menarche (age at onset); TGCT cis rs7659604 0.967 rs10008348 chr4:122666987 A/C cg19748678 chr4:122722346 EXOSC9 0.55 5.31 0.43 4.92e-7 Type 2 diabetes; TGCT cis rs1570884 0.516 rs7334387 chr13:50172133 T/A cg03651054 chr13:50194643 NA 0.33 5.28 0.43 5.66e-7 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs1008375 0.966 rs2315553 chr4:17627332 T/C cg18681998 chr4:17616180 MED28 1.08 12.13 0.74 8.24e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1008375 1.000 rs10009541 chr4:17682218 C/T cg16339924 chr4:17578868 LAP3 -0.59 -4.97 -0.41 2.13e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4660261 0.526 rs2485997 chr1:44345841 G/C cg12908607 chr1:44402522 ARTN -0.67 -8.24 -0.59 2.12e-13 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs727505 0.821 rs67167896 chr7:124614127 T/C cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs228437 0.565 rs11759614 chr6:134962916 A/G cg09872934 chr6:134495829 SGK1 0.53 4.56 0.38 1.21e-5 Melanoma; TGCT cis rs7655441 1.000 rs7692932 chr4:80919178 G/A cg02241357 chr4:80885279 ANTXR2 -0.24 -4.59 -0.38 1.07e-5 Neutrophil percentage of white cells; TGCT cis rs7582180 0.627 rs6749018 chr2:101001859 G/T cg08017756 chr2:100939284 LONRF2 -0.32 -5.37 -0.43 3.72e-7 Intelligence (multi-trait analysis); TGCT cis rs1894292 0.527 rs4267704 chr4:74376022 T/C cg05868023 chr4:75230803 EREG 0.56 5.05 0.41 1.56e-6 Prostate cancer; TGCT cis rs12765878 0.580 rs11191822 chr10:105599770 T/G cg11005552 chr10:105648138 OBFC1 -0.39 -6.05 -0.48 1.6e-8 Coronary artery disease; TGCT cis rs2204008 0.774 rs12810027 chr12:38212165 A/G cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs2067615 0.579 rs10778506 chr12:107143260 T/C cg15890332 chr12:107067104 RFX4 0.29 5.63 0.45 1.14e-7 Heart rate; TGCT cis rs7772486 0.846 rs9403767 chr6:146402386 G/T cg23711669 chr6:146136114 FBXO30 0.9 9.97 0.67 1.46e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10489525 0.599 rs17033129 chr1:115611539 C/T cg12756093 chr1:115239321 AMPD1 -0.37 -4.95 -0.41 2.35e-6 Autism; TGCT cis rs2836950 0.585 rs1029004 chr21:40615343 A/G cg17971929 chr21:40555470 PSMG1 -0.51 -4.61 -0.38 9.97e-6 Menarche (age at onset); TGCT trans rs561341 0.843 rs2028067 chr17:30239698 T/C cg20587970 chr11:113659929 NA -0.85 -10.92 -0.7 7.41e-20 Hip circumference adjusted for BMI; TGCT cis rs8062405 0.737 rs11861132 chr16:28871860 A/G cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1577917 0.958 rs28442244 chr6:86701236 G/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 4.96 0.41 2.24e-6 Response to antipsychotic treatment; TGCT cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg26818010 chr10:134567672 INPP5A -0.37 -5.02 -0.41 1.74e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs17270561 0.779 rs78589800 chr6:25883500 C/G cg16482183 chr6:26056742 HIST1H1C 0.89 6.63 0.51 9.23e-10 Iron status biomarkers; TGCT cis rs1552244 0.810 rs4019706 chr3:10112862 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs7091068 0.518 rs4919436 chr10:95461475 C/T cg20715218 chr10:95462985 C10orf4 0.52 5.51 0.44 1.99e-7 Urinary tract infection frequency; TGCT cis rs7772486 0.597 rs6912351 chr6:146264071 T/C cg23711669 chr6:146136114 FBXO30 -0.74 -6.96 -0.53 1.75e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.871 rs10504227 chr8:58162005 G/A cg24829409 chr8:58192753 C8orf71 -0.54 -4.99 -0.41 2.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs9303401 0.659 rs35797125 chr17:56736547 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs10751667 0.621 rs10794353 chr11:948740 A/G cg06064525 chr11:970664 AP2A2 -0.35 -7.92 -0.58 1.15e-12 Alzheimer's disease (late onset); TGCT cis rs7772486 0.790 rs2247666 chr6:146220409 C/A cg23711669 chr6:146136114 FBXO30 0.91 10.65 0.69 3.26e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6089829 0.888 rs6011559 chr20:61675620 C/T cg18188782 chr20:61659543 NA -0.45 -4.86 -0.4 3.52e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs6074578 0.679 rs12626088 chr20:139154 A/G cg16931068 chr20:139680 DEFB127 0.26 4.48 0.37 1.69e-5 Hirschsprung disease; TGCT cis rs117785887 0.536 rs12192366 chr6:146409990 A/G cg06708562 chr6:146285465 SHPRH -0.8 -4.79 -0.4 4.66e-6 Interleukin-17 levels; TGCT cis rs736408 0.562 rs13071584 chr3:52804487 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -4.88 -0.4 3.2e-6 Bipolar disorder; TGCT cis rs873946 0.564 rs2803991 chr10:134557068 A/G cg18305652 chr10:134549665 INPP5A 0.31 5.12 0.42 1.11e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs453301 0.658 rs13271797 chr8:8885954 G/A cg11995313 chr8:8860691 ERI1 0.54 4.73 0.39 6.09e-6 Joint mobility (Beighton score); TGCT cis rs1005277 0.691 rs2474558 chr10:38486141 A/C cg25427524 chr10:38739819 LOC399744 0.38 6.63 0.51 9.48e-10 Extrinsic epigenetic age acceleration; TGCT cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg13397359 chr6:42928475 GNMT 0.72 6.48 0.5 1.94e-9 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9325144 0.624 rs10783330 chr12:39114084 A/G cg26384229 chr12:38710491 ALG10B -0.62 -5.69 -0.46 8.48e-8 Morning vs. evening chronotype; TGCT cis rs7412746 0.658 rs59024312 chr1:150909005 T/G cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs6665290 0.904 rs11586604 chr1:227183865 G/T cg10327440 chr1:227177885 CDC42BPA -0.99 -20.27 -0.88 3.54e-41 Myeloid white cell count; TGCT cis rs72781680 1.000 rs72781667 chr2:24225667 A/G cg08917208 chr2:24149416 ATAD2B 0.76 4.67 0.39 7.83e-6 Lymphocyte counts; TGCT cis rs7260538 0.808 rs1552219 chr19:41525374 A/G cg27089200 chr19:41531976 NA 0.45 5.88 0.47 3.63e-8 DDT metabolite (p,p'-DDE levels); TGCT cis rs7582180 0.629 rs13025184 chr2:100944842 A/G cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2067615 0.542 rs10861654 chr12:107122896 A/G cg15890332 chr12:107067104 RFX4 0.3 5.99 0.47 2.11e-8 Heart rate; TGCT cis rs7914558 1.000 rs7911789 chr10:104756374 T/C cg04362960 chr10:104952993 NT5C2 0.62 5.49 0.44 2.14e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs17221829 0.733 rs72971011 chr11:89358858 A/G cg02982614 chr11:89391479 FOLH1B -0.28 -4.87 -0.4 3.35e-6 Anxiety in major depressive disorder; TGCT cis rs12142240 0.698 rs7515284 chr1:46809419 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs1865760 0.602 rs2157050 chr6:26020431 C/T cg17042849 chr6:26104293 HIST1H4C -0.61 -5.13 -0.42 1.07e-6 Height; TGCT cis rs78487399 0.808 rs6746610 chr2:43677253 T/A cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs172166 0.694 rs188105 chr6:28071393 C/T cg10876282 chr6:28092338 ZSCAN16 0.51 4.79 0.39 4.75e-6 Cardiac Troponin-T levels; TGCT cis rs2153535 0.541 rs9392222 chr6:8467649 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs1218582 0.772 rs2174507 chr1:154887949 C/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg20007245 chr22:24372913 LOC391322 0.8 6.75 0.52 4.96e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs62244186 0.659 rs12108134 chr3:44543030 A/G cg04389838 chr3:44770851 ZNF501 0.38 4.94 0.41 2.49e-6 Depressive symptoms; TGCT cis rs12776158 1.000 rs34618077 chr10:71216134 T/C cg12610070 chr10:71211762 TSPAN15 -0.55 -4.83 -0.4 3.87e-6 Age-related hearing impairment (SNP x SNP interaction); TGCT cis rs380904 1.000 rs12543128 chr8:144595042 G/A cg22012530 chr8:144635309 GSDMD 0.47 4.89 0.4 3.03e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs1865760 0.663 rs9379815 chr6:25980116 T/A cg17042849 chr6:26104293 HIST1H4C -0.59 -5.43 -0.44 2.91e-7 Height; TGCT cis rs28595532 0.844 rs55845920 chr4:119490085 C/T cg14228332 chr4:119757509 SEC24D 1.0 5.75 0.46 6.54e-8 Cannabis dependence symptom count; TGCT trans rs9650657 0.504 rs10108347 chr8:11033517 G/C cg15556689 chr8:8085844 FLJ10661 -0.74 -6.81 -0.52 3.65e-10 Neuroticism; TGCT cis rs10892173 0.566 rs12364667 chr11:117675286 A/C cg04064380 chr11:117688259 NA -0.5 -4.48 -0.37 1.7e-5 Myopia; TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg15242686 chr22:24348715 GSTTP1 -0.42 -5.64 -0.45 1.07e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13191362 0.810 rs28360533 chr6:162996742 A/G cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs644799 0.965 rs598876 chr11:95560853 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.52 0.69 6.75e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs8177253 0.763 rs6797713 chr3:133474832 T/C cg08048268 chr3:133502702 NA -0.54 -7.21 -0.54 4.93e-11 Iron status biomarkers; TGCT cis rs78487399 0.908 rs6749617 chr2:43845329 A/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 -0.63 -4.62 -0.38 9.47e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs3809566 0.963 rs4775608 chr15:63331940 A/G cg05507819 chr15:63340323 TPM1 0.48 4.52 0.38 1.4e-5 Platelet count; TGCT cis rs6089584 0.819 rs1467593 chr20:60601432 T/G cg13665807 chr20:60559372 TAF4 0.47 5.04 0.41 1.62e-6 Body mass index; TGCT cis rs28595532 1.000 rs17258106 chr4:119675406 C/T cg11846333 chr4:119757529 SEC24D -0.9 -4.94 -0.41 2.51e-6 Cannabis dependence symptom count; TGCT cis rs12477438 0.520 rs4340581 chr2:99725025 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.22 0.85 7.28e-37 Chronic sinus infection; TGCT cis rs6901004 0.835 rs1150079 chr6:111471425 A/T cg15721981 chr6:111408429 SLC16A10 -0.53 -4.67 -0.39 7.84e-6 Blood metabolite levels; TGCT cis rs12210905 1.000 rs72843615 chr6:27150569 C/T cg08851530 chr6:28072375 NA 1.12 5.43 0.44 2.82e-7 Hip circumference adjusted for BMI; TGCT cis rs2702888 0.501 rs2741718 chr8:6746641 A/G cg26795848 chr8:6756730 NA -0.32 -6.39 -0.5 3e-9 Blood pressure; TGCT cis rs2797160 0.515 rs9375409 chr6:125972798 A/G cg05901451 chr6:126070800 HEY2 -0.63 -5.35 -0.43 4.14e-7 Endometrial cancer; TGCT cis rs4319547 0.915 rs3803005 chr12:123110654 T/C cg23029597 chr12:123009494 RSRC2 -0.3 -4.92 -0.4 2.74e-6 Body mass index; TGCT cis rs7412746 0.658 rs10305711 chr1:150802996 T/C cg09365446 chr1:150670422 GOLPH3L 0.35 5.16 0.42 9.31e-7 Melanoma; TGCT cis rs6121246 0.567 rs6060297 chr20:30198560 A/G cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs981844 0.857 rs62325139 chr4:154712213 C/T cg14289246 chr4:154710475 SFRP2 1.05 9.32 0.64 5.44e-16 Response to statins (LDL cholesterol change); TGCT trans rs1973993 0.967 rs1555543 chr1:96944797 A/C cg10631902 chr5:14652156 NA 0.3 6.94 0.53 1.97e-10 Weight; TGCT cis rs240764 0.631 rs6932158 chr6:101246010 T/C cg21058520 chr6:100914733 NA 0.35 4.56 0.38 1.22e-5 Neuroticism; TGCT cis rs941408 0.515 rs878893 chr19:2781325 A/G cg17333051 chr19:2783644 SGTA 0.36 4.48 0.37 1.66e-5 Total cholesterol levels; TGCT cis rs344364 0.511 rs1742395 chr16:1955965 G/A cg26617929 chr16:1858877 NA -0.25 -4.48 -0.37 1.69e-5 Glomerular filtration rate in chronic kidney disease; TGCT cis rs9303401 0.580 rs12603808 chr17:56578508 T/G cg02118635 chr17:56770003 RAD51C;TEX14 0.63 6.36 0.5 3.54e-9 Cognitive test performance; TGCT cis rs4733781 0.901 rs4733777 chr8:131271562 C/T cg16277922 chr8:131349729 ASAP1 0.36 4.61 0.38 9.92e-6 Tuberculosis; TGCT cis rs7364180 0.582 rs139568 chr22:42210985 C/T cg03806693 chr22:41940476 POLR3H 0.62 6.23 0.49 6.66e-9 Alzheimer's disease biomarkers; TGCT cis rs10256972 0.553 rs4236381 chr7:1165723 A/C cg07092213 chr7:1199455 ZFAND2A -0.45 -4.86 -0.4 3.5e-6 Longevity;Endometriosis; TGCT cis rs9915657 0.870 rs34129640 chr17:70125665 A/C cg06234051 chr17:70120541 SOX9 -0.27 -5.43 -0.44 2.88e-7 Thyroid hormone levels; TGCT cis rs2996428 0.643 rs6424056 chr1:3722486 G/A cg17848003 chr1:3704513 LRRC47 0.17 4.63 0.38 9.05e-6 Red cell distribution width; TGCT cis rs8064299 0.503 rs11653346 chr17:72773333 A/G cg25054828 chr17:72772726 NAT9;TMEM104 0.59 5.5 0.44 2.09e-7 Monocyte count; TGCT cis rs11671005 0.735 rs11671591 chr19:58918337 A/G cg13877915 chr19:58951672 ZNF132 -0.69 -5.58 -0.45 1.46e-7 Mean platelet volume; TGCT cis rs801193 0.591 rs2707839 chr7:66193084 A/G cg18876405 chr7:65276391 NA 0.33 4.88 0.4 3.15e-6 Aortic root size; TGCT cis rs778371 1.000 rs709937 chr2:233744021 A/G cg08000102 chr2:233561755 GIGYF2 0.6 6.48 0.5 1.95e-9 Schizophrenia; TGCT cis rs17102423 0.788 rs35176994 chr14:65596004 T/C cg11161011 chr14:65562177 MAX -0.55 -7.37 -0.55 2.09e-11 Obesity-related traits; TGCT cis rs9325144 0.600 rs1817648 chr12:38733424 C/T cg26384229 chr12:38710491 ALG10B -0.62 -5.81 -0.46 5.06e-8 Morning vs. evening chronotype; TGCT cis rs3617 0.625 rs11922961 chr3:52868610 T/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.53 -0.38 1.35e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1941023 0.606 rs7946122 chr11:60172770 G/A cg08716584 chr11:60157161 MS4A7 -0.31 -4.69 -0.39 7.18e-6 Congenital heart disease (maternal effect); TGCT cis rs3617 0.532 rs9836499 chr3:52904524 G/T cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.91 0.4 2.77e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs4242434 0.892 rs11776549 chr8:22493124 C/T cg03733263 chr8:22462867 KIAA1967 1.07 15.12 0.81 6.42e-30 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs2295359 0.824 rs4655679 chr1:67599657 A/G cg12940439 chr1:67600707 NA -0.63 -6.66 -0.51 7.99e-10 Psoriasis; TGCT cis rs7647973 1.000 rs11928090 chr3:49604904 G/A cg07690219 chr3:49449608 TCTA;RHOA -0.56 -4.76 -0.39 5.24e-6 Menarche (age at onset); TGCT cis rs1218582 0.772 rs2174507 chr1:154887949 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs11719291 0.833 rs11715835 chr3:48770732 C/T cg07636037 chr3:49044803 WDR6 -0.98 -5.09 -0.42 1.27e-6 Cognitive function; TGCT cis rs875971 1.000 rs6956179 chr7:65806659 C/T cg18876405 chr7:65276391 NA -0.35 -5.46 -0.44 2.44e-7 Aortic root size; TGCT cis rs62244186 0.566 rs55901755 chr3:44834707 C/T cg21672276 chr3:44754072 ZNF502 -0.55 -6.31 -0.49 4.58e-9 Depressive symptoms; TGCT cis rs9457247 0.508 rs7760495 chr6:167506795 C/T cg07741184 chr6:167504864 NA 0.27 5.25 0.43 6.4e-7 Crohn's disease; TGCT cis rs9916302 0.851 rs9904919 chr17:37556431 G/C cg15445000 chr17:37608096 MED1 -0.34 -4.8 -0.4 4.43e-6 Glomerular filtration rate (creatinine); TGCT cis rs3099143 1.000 rs3110378 chr15:77127983 G/A cg21673338 chr15:77095150 SCAPER -0.51 -4.88 -0.4 3.17e-6 Recalcitrant atopic dermatitis; TGCT cis rs56104184 0.830 rs73061622 chr19:49358111 C/T cg15549821 chr19:49342101 PLEKHA4 -0.78 -9.12 -0.63 1.66e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4819052 0.851 rs7279182 chr21:46656112 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.69 6.07 0.48 1.41e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6754311 0.773 rs309176 chr2:136622216 T/C cg07169764 chr2:136633963 MCM6 -0.63 -5.88 -0.47 3.51e-8 Mosquito bite size; TGCT cis rs59698941 0.550 rs12652469 chr5:132182765 A/G cg21474247 chr5:131268130 NA 0.31 4.97 0.41 2.16e-6 Apolipoprotein A-IV levels; TGCT cis rs9399135 0.967 rs9402676 chr6:135355507 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.77 0.39 5.14e-6 Red blood cell count; TGCT cis rs72945132 0.714 rs115143889 chr11:70150122 G/T cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs28386778 0.897 rs57108948 chr17:61802378 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT trans rs1880529 0.830 rs6533687 chr4:114365275 C/T cg19626253 chr1:15062529 KIAA1026 0.3 6.79 0.52 4.11e-10 White matter integrity (bipolar disorder risk interaction); TGCT cis rs7000551 0.725 rs1075534 chr8:22374074 A/G cg12081754 chr8:22256438 SLC39A14 0.29 4.71 0.39 6.56e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs8070128 0.583 rs7406982 chr17:17942613 C/T cg04398451 chr17:18023971 MYO15A -0.33 -5.28 -0.43 5.67e-7 Total body bone mineral density; TGCT cis rs3741404 1.000 rs11603042 chr11:64003843 G/T cg01727686 chr11:63997306 NUDT22;DNAJC4 0.22 4.68 0.39 7.26e-6 Platelet count; TGCT cis rs548181 0.736 rs497344 chr11:125470524 T/C cg03464685 chr11:125439445 EI24 1.14 8.16 0.59 3.1400000000000003e-13 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2224391 0.554 rs114825667 chr6:5242618 A/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.02 -6.47 -0.5 2.04e-9 Height; TGCT cis rs6903823 0.508 rs1150718 chr6:28256947 C/A cg18815343 chr6:28367644 ZSCAN12 -0.44 -4.65 -0.39 8.28e-6 Pulmonary function; TGCT cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs12220238 1.000 rs7073432 chr10:75953350 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7714584 1.000 rs59715748 chr5:150189287 G/A cg22134413 chr5:150180641 NA 1.13 8.18 0.59 2.91e-13 Crohn's disease; TGCT cis rs7811142 1.000 rs7783550 chr7:99987805 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 -1.05 -8.95 -0.63 4.39e-15 Platelet count; TGCT cis rs4523957 0.651 rs7212342 chr17:2084305 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7829975 0.511 rs1401390 chr8:8136410 C/T cg15556689 chr8:8085844 FLJ10661 0.84 8.03 0.59 6.29e-13 Mood instability; TGCT cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.56 -5.53 -0.45 1.77e-7 Intelligence (multi-trait analysis); TGCT cis rs2765041 1 rs2765041 chr14:103991478 T/A cg26031613 chr14:104095156 KLC1 0.56 4.67 0.39 7.74e-6 High light scatter reticulocyte count; TGCT cis rs651907 0.557 rs34376498 chr3:101480156 C/T cg11279151 chr3:101281821 RG9MTD1 -0.33 -6.8 -0.52 3.91e-10 Colorectal cancer; TGCT cis rs3784262 0.669 rs12595180 chr15:58332541 G/C cg12031962 chr15:58353849 ALDH1A2 -0.43 -6.19 -0.49 8.07e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT trans rs931812 0.757 rs34988706 chr8:101907062 C/T cg20993868 chr7:22813445 NA 0.32 6.63 0.51 9.13e-10 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs975752 0.867 rs11190444 chr10:102024352 C/T cg04750910 chr10:102416409 NA 0.73 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs9916302 0.768 rs62077464 chr17:37656056 C/G cg15445000 chr17:37608096 MED1 0.31 4.57 0.38 1.18e-5 Glomerular filtration rate (creatinine); TGCT cis rs13191362 1.000 rs4489133 chr6:163137793 C/T cg06582575 chr6:163149167 PACRG;PARK2 1.0 7.73 0.57 3.24e-12 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1513670 1.000 rs8071941 chr17:41810313 A/G cg10758466 chr17:41974087 MPP2 -0.28 -4.55 -0.38 1.27e-5 Bone mineral density (hip); TGCT cis rs7208859 0.623 rs7223404 chr17:29107363 C/T cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7772486 0.686 rs2179323 chr6:145982786 T/G cg05347473 chr6:146136440 FBXO30 -0.48 -4.52 -0.38 1.42e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs74233809 1.000 rs11191453 chr10:104659852 T/C cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs9527 0.640 rs35195396 chr10:104928770 T/A cg15744005 chr10:104629667 AS3MT -0.4 -4.59 -0.38 1.08e-5 Arsenic metabolism; TGCT cis rs7267979 0.903 rs2474766 chr20:25246153 A/G cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11264213 0.591 rs274728 chr1:36493420 T/C cg27506609 chr1:36549197 TEKT2 -0.47 -5.33 -0.43 4.54e-7 Schizophrenia; TGCT cis rs1048238 0.506 rs848209 chr1:16256007 T/C cg22431228 chr1:16359049 CLCNKA 0.23 4.48 0.37 1.67e-5 Systolic blood pressure; TGCT cis rs1887596 0.663 rs3794413 chr13:27250945 A/G cg01312412 chr13:27282625 NA 0.28 4.98 0.41 2.07e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs6582630 0.555 rs10880625 chr12:38526612 A/C cg13010199 chr12:38710504 ALG10B 0.65 5.18 0.42 8.78e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs7246657 0.943 rs7246993 chr19:37890154 C/T cg18154014 chr19:37997991 ZNF793 0.95 6.63 0.51 9.39e-10 Coronary artery calcification; TGCT cis rs9357506 1.000 rs6911474 chr6:46307667 G/T cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs7017914 0.967 rs2100908 chr8:71583310 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs1577917 0.652 rs75593931 chr6:86719539 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs6964587 0.967 rs28399886 chr7:91638451 A/G cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs9303401 0.659 rs12948133 chr17:56673602 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs910316 1.000 rs12588240 chr14:75612083 C/A cg23033748 chr14:75592666 NEK9 0.28 4.79 0.39 4.73e-6 Height; TGCT trans rs28595532 0.702 rs116320061 chr4:119384600 C/T cg26518628 chr1:97050305 NA -0.54 -6.85 -0.52 2.98e-10 Cannabis dependence symptom count; TGCT cis rs72781680 1.000 rs12617839 chr2:24166277 A/T cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs11671005 0.693 rs11668757 chr19:58928299 A/T cg13877915 chr19:58951672 ZNF132 0.63 4.99 0.41 1.95e-6 Mean platelet volume; TGCT cis rs1406084 0.636 rs3843319 chr2:154717586 G/C cg25703346 chr2:154729189 GALNT13 0.77 4.6 0.38 1.03e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs2730245 0.527 rs1188974 chr7:158665748 C/T cg11984989 chr7:158649758 WDR60 1.01 7.84 0.58 1.79e-12 Height; TGCT cis rs11783469 0.522 rs11781871 chr8:23257090 C/T cg00472375 chr8:23315376 ENTPD4 0.7 5.64 0.45 1.08e-7 Reticulocyte count; TGCT cis rs10504229 1.000 rs112284078 chr8:58191640 A/G cg08280861 chr8:58055591 NA 0.36 4.82 0.4 4.2e-6 Developmental language disorder (linguistic errors); TGCT cis rs12753569 0.720 rs4381138 chr1:76509783 G/A cg00791851 chr1:76518896 NA 0.35 4.6 0.38 1.04e-5 Personality dimensions; TGCT cis rs1997103 1.000 rs9649851 chr7:55398692 C/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7809950 1.000 rs3801948 chr7:107238447 A/T cg23024343 chr7:107201750 COG5 -0.35 -5.42 -0.44 2.94e-7 Coronary artery disease; TGCT cis rs7589728 0.514 rs74426843 chr2:88459388 C/T cg04511125 chr2:88470314 THNSL2 0.79 6.55 0.51 1.37e-9 Plasma clusterin levels; TGCT cis rs2544527 0.557 rs2112101 chr2:15902679 C/T cg26669897 chr2:15909070 NA -0.42 -4.89 -0.4 3.08e-6 Pulmonary function (smoking interaction);Pulmonary function; TGCT cis rs2224391 0.911 rs6925249 chr6:5262510 G/T cg09085698 chr6:5261316 LYRM4;FARS2 -0.79 -6.05 -0.48 1.61e-8 Height; TGCT cis rs11112613 0.713 rs17041546 chr12:105950801 G/T cg03607813 chr12:105948248 NA -0.52 -6.28 -0.49 5.28e-9 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs8177179 0.967 rs9869311 chr3:133451613 C/T cg16262614 chr3:133464971 TF 0.35 4.72 0.39 6.28e-6 Iron status biomarkers (transferrin levels); TGCT cis rs75059851 0.756 rs11223661 chr11:133851412 G/T cg14047540 chr11:133829660 NA -0.54 -4.97 -0.41 2.21e-6 Schizophrenia; TGCT cis rs12908161 1.000 rs12911736 chr15:85240008 A/G cg12863693 chr15:85201151 NMB 0.46 5.53 0.44 1.79e-7 Schizophrenia; TGCT cis rs12477438 0.765 rs4374423 chr2:99662348 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs2072499 0.966 rs2842882 chr1:156165342 T/G cg24450063 chr1:156163899 SLC25A44 1.2 18.21 0.85 7.43e-37 Testicular germ cell tumor; TGCT cis rs2153535 0.580 rs9406174 chr6:8516764 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs3617 0.625 rs7652667 chr3:52866535 C/A cg10802521 chr3:52805072 NEK4 0.62 7.17 0.54 6e-11 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10170846 0.530 rs56353541 chr2:223421187 G/C cg25565276 chr2:223520875 FARSB 0.75 6.01 0.47 1.95e-8 Schizophrenia (inflammation and infection response interaction); TGCT cis rs7845219 0.525 rs10956931 chr8:95930301 A/G cg13393036 chr8:95962371 TP53INP1 -0.42 -4.89 -0.4 3.08e-6 Type 2 diabetes; TGCT cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg05985448 chr10:134359359 INPP5A 0.22 4.83 0.4 3.89e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs829883 0.664 rs249833 chr12:98832189 T/C cg25150519 chr12:98850993 NA 0.62 7.36 0.55 2.2e-11 Colorectal adenoma (advanced); TGCT cis rs2243480 0.803 rs36127118 chr7:65565505 A/G cg07424592 chr7:64974309 NA 1.25 8.11 0.59 4.21e-13 Diabetic kidney disease; TGCT cis rs10782582 0.609 rs78748984 chr1:76340467 G/A cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs13272623 0.502 rs268601 chr8:71518548 C/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.61 -5.16 -0.42 9.64e-7 IgG glycosylation; TGCT cis rs2420915 0.841 rs7072051 chr10:122873110 A/T cg23234726 chr10:122735589 NA -0.39 -4.49 -0.37 1.6e-5 Fibrinogen levels; TGCT cis rs7937682 0.921 rs12806479 chr11:111443192 G/C cg09085632 chr11:111637200 PPP2R1B 0.87 7.28 0.55 3.34e-11 Primary sclerosing cholangitis; TGCT cis rs9322193 0.884 rs10872648 chr6:150079835 A/G cg13206674 chr6:150067644 NUP43 0.54 4.65 0.39 8.48e-6 Lung cancer; TGCT cis rs1200821 0.559 rs9418267 chr10:37819951 A/G cg25427524 chr10:38739819 LOC399744 0.3 5.27 0.43 5.89e-7 Hemostatic factors and hematological phenotypes; TGCT cis rs7824557 0.564 rs2736288 chr8:11228100 G/A cg21775007 chr8:11205619 TDH -0.65 -6.14 -0.48 1.01e-8 Retinal vascular caliber; TGCT cis rs875971 1.000 rs1167411 chr7:65539264 C/G cg11764359 chr7:65958608 NA -0.56 -4.7 -0.39 6.74e-6 Aortic root size; TGCT cis rs3806843 0.576 rs155358 chr5:140297032 A/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.44 -5.32 -0.43 4.6e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs344364 0.511 rs1742468 chr16:1950243 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs10992471 0.603 rs10992342 chr9:95212068 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.62 -5.74 -0.46 6.79e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs6450176 0.909 rs6884760 chr5:53293077 T/A ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.59 -0.38 1.08e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs314370 0.570 rs314324 chr7:100433794 C/T cg10426581 chr7:100472382 SRRT 0.74 7.72 0.57 3.37e-12 Resting heart rate; TGCT cis rs7847628 0.666 rs2031974 chr9:123527521 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.52 4.75 0.39 5.42e-6 Birth weight; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg08859206 chr1:53392774 SCP2 0.42 6.44 0.5 2.32e-9 Monocyte count; TGCT cis rs7552404 1.000 rs7548962 chr1:76139266 G/A cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2535633 0.594 rs2581789 chr3:53096230 C/T cg10802521 chr3:52805072 NEK4 0.5 5.38 0.43 3.6e-7 Body mass index; TGCT cis rs903263 0.965 rs1402694 chr1:84600513 C/T cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.73e-6 Breast cancer (male); TGCT cis rs7937890 1.000 rs2970335 chr11:14325401 A/C cg19336497 chr11:14380999 RRAS2 -0.3 -4.8 -0.4 4.4e-6 Mitochondrial DNA levels; TGCT cis rs6121246 0.954 rs6089093 chr20:30421459 C/T cg13852791 chr20:30311386 BCL2L1 0.79 5.6 0.45 1.33e-7 Mean corpuscular hemoglobin; TGCT cis rs4478858 0.735 rs6425736 chr1:31784376 T/A cg00250761 chr1:31883323 NA -0.28 -5.01 -0.41 1.86e-6 Alcohol dependence; TGCT cis rs447921 0.813 rs435892 chr17:74398505 A/T cg09812376 chr17:74270190 QRICH2 0.46 4.6 0.38 1.01e-5 Mitochondrial DNA levels; TGCT cis rs509477 0.887 rs657018 chr18:32558960 C/T cg23791764 chr18:32556832 MAPRE2 0.77 6.54 0.51 1.42e-9 Cerebrospinal fluid AB1-42 levels; TGCT cis rs40363 0.645 rs250627 chr16:3527050 G/A cg22508957 chr16:3507546 NAT15 0.47 5.3 0.43 5.1e-7 Tuberculosis; TGCT cis rs3784262 1.000 rs4646593 chr15:58302467 A/G cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.82 -0.57 1.98e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2760061 0.784 rs708116 chr1:228198196 C/A cg18477163 chr1:228402036 OBSCN 0.34 7.19 0.54 5.33e-11 Diastolic blood pressure; TGCT cis rs9611565 0.512 rs139573 chr22:42214785 G/A cg03806693 chr22:41940476 POLR3H -1.04 -10.57 -0.69 5.2e-19 Vitiligo; TGCT cis rs6545883 0.718 rs6715259 chr2:61851845 G/T cg15711740 chr2:61764176 XPO1 -0.59 -5.39 -0.44 3.45e-7 Tuberculosis; TGCT cis rs9814567 1.000 rs12637751 chr3:134266124 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7959452 0.535 rs10784771 chr12:69621264 A/G cg20891283 chr12:69753455 YEATS4 0.62 5.85 0.47 4.04e-8 Blood protein levels; TGCT cis rs7017914 0.934 rs7015035 chr8:71653601 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs6534347 0.573 rs1398554 chr4:123522569 G/A cg10583651 chr4:123538969 IL21 -0.36 -5.27 -0.43 5.97e-7 Type 1 diabetes; TGCT cis rs7937682 0.889 rs2850247 chr11:111637202 C/A cg09085632 chr11:111637200 PPP2R1B 1.24 15.61 0.81 4.86e-31 Primary sclerosing cholangitis; TGCT cis rs2455799 0.573 rs2174172 chr3:15768579 C/A cg16303742 chr3:15540471 COLQ -0.26 -5.02 -0.41 1.76e-6 Mean platelet volume; TGCT cis rs7666738 1.000 rs1426673 chr4:98924024 G/A cg17366294 chr4:99064904 C4orf37 0.72 6.58 0.51 1.17e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg25767906 chr1:53392781 SCP2 -0.59 -7.49 -0.56 1.12e-11 Monocyte count; TGCT cis rs8180040 0.522 rs749512 chr3:47035900 C/T cg27129171 chr3:47204927 SETD2 -0.66 -7.54 -0.56 8.87e-12 Colorectal cancer; TGCT cis rs6674176 0.561 rs7161 chr1:44438974 A/G cg13606994 chr1:44402422 ARTN 0.45 4.92 0.4 2.64e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs6901250 0.851 rs339322 chr6:117193356 T/C cg12892004 chr6:117198278 RFX6 -0.57 -7.0 -0.53 1.46e-10 C-reactive protein levels; TGCT cis rs2224391 1.000 rs2224391 chr6:5260936 A/C cg09085698 chr6:5261316 LYRM4;FARS2 -0.75 -5.62 -0.45 1.2e-7 Height; TGCT cis rs6540559 1.000 rs2235372 chr1:209960436 A/G cg04352962 chr1:209979756 IRF6 -0.6 -4.6 -0.38 1.03e-5 Cleft lip with or without cleft palate; TGCT cis rs7772486 0.686 rs2179323 chr6:145982786 T/G cg13319975 chr6:146136371 FBXO30 0.5 4.5 0.37 1.56e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.659 rs169361 chr22:41877989 A/G cg17554472 chr22:41940697 POLR3H 0.49 5.0 0.41 1.88e-6 Vitiligo; TGCT cis rs9894429 0.538 rs9747080 chr17:79606704 A/G cg21028142 chr17:79581711 NPLOC4 0.29 6.01 0.48 1.9e-8 Eye color traits; TGCT cis rs7772486 0.875 rs6570738 chr6:146412695 G/A cg05347473 chr6:146136440 FBXO30 0.53 5.03 0.41 1.71e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9325144 0.560 rs1843911 chr12:38676585 C/T cg26384229 chr12:38710491 ALG10B -0.69 -6.57 -0.51 1.26e-9 Morning vs. evening chronotype; TGCT cis rs80282103 0.618 rs11250252 chr10:1124939 G/C cg18964960 chr10:1102726 WDR37 0.99 4.44 0.37 2.01e-5 Glomerular filtration rate (creatinine); TGCT trans rs62103177 0.810 rs3902996 chr18:77630571 A/G cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs1670533 1.000 rs10031302 chr4:1059664 G/A cg27284194 chr4:1044797 NA 0.69 5.96 0.47 2.44e-8 Recombination rate (females); TGCT trans rs1814175 0.935 rs10839317 chr11:49657228 A/C cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs7772486 0.558 rs2142978 chr6:146012061 T/C cg23711669 chr6:146136114 FBXO30 -0.73 -6.84 -0.52 3.19e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs3733585 0.699 rs7663097 chr4:9966791 T/C cg00071950 chr4:10020882 SLC2A9 -0.57 -6.85 -0.52 3.12e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12643440 0.538 rs16894428 chr4:17142974 A/G cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT trans rs16860537 1.000 rs79583958 chr1:183229061 C/T cg10317387 chr2:88470873 THNSL2 -0.67 -6.62 -0.51 9.68e-10 Systemic lupus erythematosus and Systemic sclerosis; TGCT cis rs28735056 0.592 rs10853392 chr18:77708781 A/G cg20368463 chr18:77673604 PQLC1 -0.47 -5.5 -0.44 2.12e-7 Schizophrenia; TGCT cis rs114540395 0.858 rs77334916 chr10:103178507 T/G cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs6426558 0.515 rs7543579 chr1:227377699 A/T cg10327440 chr1:227177885 CDC42BPA -0.61 -7.07 -0.54 1.01e-10 Neutrophil percentage of white cells; TGCT cis rs13108904 0.870 rs12506095 chr4:1262233 T/C cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.82e-6 Obesity-related traits; TGCT cis rs79349575 0.715 rs4793997 chr17:47019672 C/A cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs7226408 0.749 rs4539671 chr18:34435006 T/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7020830 0.867 rs13301916 chr9:37361455 A/C cg14294708 chr9:37120828 ZCCHC7 1.21 16.97 0.84 4.05e-34 Schizophrenia; TGCT cis rs2153904 0.793 rs12748961 chr1:205676263 T/C cg23034840 chr1:205782522 SLC41A1 -0.89 -5.32 -0.43 4.66e-7 Prostate-specific antigen levels; TGCT cis rs17767294 0.708 rs72848753 chr6:27878269 C/G cg08851530 chr6:28072375 NA 1.53 7.17 0.54 6.02e-11 Parkinson's disease; TGCT cis rs9611565 0.659 rs12483998 chr22:41935362 A/G cg06634786 chr22:41940651 POLR3H -0.88 -8.54 -0.61 3.98e-14 Vitiligo; TGCT cis rs2070433 0.528 rs68063691 chr21:47759237 T/C cg12379764 chr21:47803548 PCNT 0.65 5.61 0.45 1.24e-7 Lymphocyte counts; TGCT cis rs7572733 0.515 rs700675 chr2:198700216 G/A cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs9911578 1.000 rs7216680 chr17:56988243 G/C cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.683 rs66730544 chr8:58127280 A/T cg02725872 chr8:58115012 NA -0.38 -4.99 -0.41 1.98e-6 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.600 rs35174559 chr3:49287759 T/C cg02487422 chr3:49467188 NICN1 0.55 5.32 0.43 4.77e-7 Menarche (age at onset); TGCT cis rs9346649 0.654 rs12527055 chr6:168492655 C/T cg02770688 chr6:168491649 NA 0.32 5.61 0.45 1.26e-7 Venous thromboembolism adjusted for sickle cell variant rs77121243-T; TGCT cis rs7666738 0.830 rs62318504 chr4:98935558 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9467711 1.000 rs6939978 chr6:26328462 G/C cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg12310025 chr6:25882481 NA 0.49 5.16 0.42 9.4e-7 Height; TGCT cis rs7617773 0.925 rs34513961 chr3:48173653 T/C cg11946769 chr3:48343235 NME6 0.6 4.83 0.4 3.97e-6 Coronary artery disease; TGCT cis rs7726839 0.540 rs12520279 chr5:657291 T/C cg09021430 chr5:549028 NA -0.45 -6.27 -0.49 5.56e-9 Obesity-related traits; TGCT cis rs10489202 0.632 rs12410730 chr1:168069477 T/C cg24449463 chr1:168025552 DCAF6 -0.53 -5.54 -0.45 1.75e-7 Schizophrenia; TGCT cis rs6089584 0.816 rs6061411 chr20:60634716 C/A cg12751644 chr20:60527061 NA -0.41 -4.66 -0.39 8.01e-6 Body mass index; TGCT cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg06481639 chr22:41940642 POLR3H 0.8 6.85 0.52 3.08e-10 Vitiligo; TGCT cis rs727505 0.607 rs67454509 chr7:124792500 A/G cg23710748 chr7:124431027 NA -0.26 -4.51 -0.38 1.47e-5 Lewy body disease; TGCT cis rs9486715 0.867 rs3860243 chr6:96905303 T/G cg06623918 chr6:96969491 KIAA0776 1.1 16.66 0.83 1.99e-33 Headache; TGCT trans rs11992162 0.508 rs7003792 chr8:11781464 T/C cg15556689 chr8:8085844 FLJ10661 -0.8 -6.91 -0.53 2.27e-10 Monocyte count; TGCT cis rs587847 0.737 rs4924153 chr15:37666010 A/T cg22444584 chr15:37174661 LOC145845 -0.37 -4.58 -0.38 1.09e-5 Intraocular pressure; TGCT cis rs7772486 0.720 rs6570713 chr6:146075085 G/A cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs910316 0.763 rs735452 chr14:75497984 A/G cg08847533 chr14:75593920 NEK9 -0.84 -9.19 -0.64 1.14e-15 Height; TGCT trans rs1814175 0.817 rs7481230 chr11:49772235 G/A cg15704280 chr7:45808275 SEPT13 -0.69 -8.05 -0.59 5.61e-13 Height; TGCT cis rs10927875 0.619 rs12121764 chr1:16138059 A/T cg21385522 chr1:16154831 NA -0.73 -9.15 -0.64 1.39e-15 Dilated cardiomyopathy; TGCT cis rs35306767 0.855 rs11253465 chr10:897208 A/C cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs1552244 1.000 rs7610821 chr3:10136150 C/T cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs4665630 0.522 rs2712100 chr2:23931925 A/T cg08063864 chr2:24346004 PFN4;LOC375190 -1.23 -5.86 -0.47 3.98e-8 Hypertension; TGCT cis rs250677 0.522 rs6872701 chr5:148359086 C/G cg18129178 chr5:148520854 ABLIM3 0.36 4.69 0.39 7.23e-6 Breast cancer; TGCT cis rs597539 0.689 rs596874 chr11:68630874 C/T cg06028808 chr11:68637592 NA -0.5 -6.3 -0.49 4.65e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7267979 1.000 rs6050609 chr20:25411751 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2404602 0.692 rs7169663 chr15:77192843 A/C cg22467129 chr15:76604101 ETFA -0.48 -5.45 -0.44 2.58e-7 Blood metabolite levels; TGCT cis rs9894429 1.000 rs9747349 chr17:79584297 C/T cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs10504229 0.593 rs17794451 chr8:58019217 C/T cg21724239 chr8:58056113 NA 0.47 5.05 0.41 1.54e-6 Developmental language disorder (linguistic errors); TGCT cis rs7726839 0.561 rs4957048 chr5:583442 G/A cg09021430 chr5:549028 NA -0.37 -5.23 -0.42 7.12e-7 Obesity-related traits; TGCT cis rs6087990 0.748 rs4911255 chr20:31357580 A/T cg13636640 chr20:31349939 DNMT3B 1.07 14.14 0.79 1.28e-27 Ulcerative colitis; TGCT cis rs7772486 0.597 rs9386136 chr6:146158300 A/T cg23711669 chr6:146136114 FBXO30 0.76 7.12 0.54 7.61e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs637571 0.522 rs556643 chr11:65733289 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.6 5.98 0.47 2.24e-8 Eosinophil percentage of white cells; TGCT cis rs11626933 1.000 rs7146724 chr14:90766092 C/T cg14092571 chr14:90743983 NA -0.29 -6.1 -0.48 1.26e-8 Gut microbiota (bacterial taxa); TGCT cis rs5769707 0.706 rs763128 chr22:50018045 G/A cg06623630 chr22:50017776 C22orf34 -0.27 -4.64 -0.38 8.67e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs137699 1.000 rs137699 chr22:39748854 A/G cg24399712 chr22:39784796 NA -0.66 -5.73 -0.46 7.3e-8 IgG glycosylation; TGCT cis rs478304 0.593 rs4645927 chr11:65482827 C/T cg17480646 chr11:65405466 SIPA1 -0.58 -6.56 -0.51 1.34e-9 Acne (severe); TGCT cis rs2224391 1.000 rs2753249 chr6:5263475 T/G cg09085698 chr6:5261316 LYRM4;FARS2 -0.75 -5.62 -0.45 1.2e-7 Height; TGCT cis rs2721195 0.781 rs10110962 chr8:145780323 C/T cg15320075 chr8:145703422 NA 0.71 7.1 0.54 8.74e-11 Age at first birth; TGCT cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg13342137 chr4:2252803 MXD4 -0.17 -4.6 -0.38 1.05e-5 Obesity-related traits; TGCT cis rs7666738 0.791 rs1426661 chr4:98874303 C/G cg18180107 chr4:99064573 C4orf37 0.55 5.14 0.42 1.03e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7267979 0.649 rs2500406 chr20:25401862 A/C cg03522245 chr20:25566470 NINL -0.44 -4.52 -0.38 1.43e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs68170813 0.596 rs76888321 chr7:106945926 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs11785693 0.862 rs6994323 chr8:4996786 T/A cg26367366 chr8:4980734 NA 0.58 4.45 0.37 1.91e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs12540874 0.542 rs4947581 chr7:50565967 G/A cg18232548 chr7:50535776 DDC -0.35 -6.01 -0.48 1.89e-8 Systemic sclerosis; TGCT cis rs6570726 0.791 rs385729 chr6:145855465 T/C cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.818 rs35413760 chr2:26267137 C/A cg22920501 chr2:26401640 FAM59B 0.72 5.59 0.45 1.34e-7 Gut microbiome composition (summer); TGCT cis rs7714584 1.000 rs76433514 chr5:150306532 C/G cg22134413 chr5:150180641 NA 1.04 7.44 0.56 1.48e-11 Crohn's disease; TGCT cis rs1971762 0.527 rs6580952 chr12:53937452 C/T cg16917193 chr12:54089295 NA 1.02 10.39 0.68 1.45e-18 Height; TGCT cis rs8014204 0.804 rs34956813 chr14:75254167 G/A cg06637938 chr14:75390232 RPS6KL1 0.7 6.77 0.52 4.47e-10 Caffeine consumption; TGCT cis rs7819412 0.875 rs6981523 chr8:11061792 C/T cg21775007 chr8:11205619 TDH -0.51 -4.9 -0.4 2.95e-6 Triglycerides; TGCT cis rs2032447 0.966 rs3752416 chr6:26045929 T/C cg03517284 chr6:25882590 NA -0.6 -5.35 -0.43 4.13e-7 Intelligence (multi-trait analysis); TGCT cis rs28489187 0.577 rs6697083 chr1:85887775 A/T cg16011679 chr1:85725395 C1orf52 -0.48 -4.45 -0.37 1.91e-5 Asymmetrical dimethylarginine levels;Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs9372498 0.536 rs9481825 chr6:118876092 C/T cg21191810 chr6:118973309 C6orf204 -0.37 -4.86 -0.4 3.5e-6 Diastolic blood pressure; TGCT cis rs2153535 0.504 rs9328472 chr6:8470848 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs10782582 0.609 rs5745553 chr1:76379135 A/T cg03433033 chr1:76189801 ACADM -0.5 -4.89 -0.4 3.09e-6 Daytime sleep phenotypes; TGCT cis rs617219 0.671 rs6414979 chr5:78548010 T/G cg09550809 chr5:78407562 BHMT 0.4 5.49 0.44 2.19e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6840360 0.582 rs2709823 chr4:152340446 T/C cg17479576 chr4:152424074 FAM160A1 -0.57 -5.98 -0.47 2.17e-8 Intelligence (multi-trait analysis); TGCT cis rs896854 0.812 rs12546365 chr8:95911477 T/C cg16049864 chr8:95962084 TP53INP1 -0.7 -9.71 -0.66 6.27e-17 Type 2 diabetes; TGCT cis rs35771425 0.626 rs55761812 chr1:211653935 C/T cg10512769 chr1:211675356 NA -0.25 -4.49 -0.37 1.59e-5 Educational attainment (years of education); TGCT cis rs9311474 0.508 rs6786043 chr3:52604861 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Electroencephalogram traits; TGCT cis rs7513165 0.932 rs11240694 chr1:204157973 C/T cg12731349 chr1:204159619 KISS1 0.5 5.51 0.44 1.94e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs1757171 0.542 rs1757186 chr6:37484111 A/G cg01843034 chr6:37503916 NA -0.54 -7.33 -0.55 2.57e-11 Cognitive performance; TGCT cis rs34779708 0.898 rs4934695 chr10:35280605 C/T cg04310649 chr10:35416472 CREM -0.51 -4.55 -0.38 1.24e-5 Inflammatory bowel disease;Crohn's disease; TGCT cis rs1483890 0.723 rs6549208 chr3:69412134 T/G cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs4711350 0.862 rs602399 chr6:33713779 C/T cg00334056 chr6:33755658 LEMD2 0.31 4.81 0.4 4.31e-6 Schizophrenia; TGCT cis rs6714710 0.603 rs11681535 chr2:98488949 G/C cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs9611565 0.918 rs4822024 chr22:41757647 G/A cg17554472 chr22:41940697 POLR3H -0.47 -4.79 -0.4 4.59e-6 Vitiligo; TGCT cis rs7945705 0.870 rs10840142 chr11:8906078 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.42 4.7 0.39 6.86e-6 Hemoglobin concentration; TGCT cis rs477895 0.653 rs11602181 chr11:63896591 C/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.77 6.24 0.49 6.22e-9 Mean platelet volume; TGCT cis rs752010 0.746 rs11210499 chr1:42089703 C/T cg06885757 chr1:42089581 HIVEP3 -0.25 -4.49 -0.37 1.62e-5 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs17376456 0.597 rs10064158 chr5:93095186 C/T cg21475434 chr5:93447410 FAM172A 0.61 4.95 0.41 2.35e-6 Diabetic retinopathy; TGCT cis rs9303401 0.659 rs62081316 chr17:56781499 C/T cg25039879 chr17:56429692 SUPT4H1 0.52 4.62 0.38 9.48e-6 Cognitive test performance; TGCT cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.52 -4.9 -0.4 2.9e-6 Bipolar disorder; TGCT cis rs854765 0.663 rs4925120 chr17:17754633 C/T cg04398451 chr17:18023971 MYO15A 0.29 4.52 0.38 1.44e-5 Total body bone mineral density; TGCT trans rs877282 1.000 rs71494928 chr10:769134 A/G cg22713356 chr15:30763199 NA 1.25 10.39 0.68 1.43e-18 Uric acid levels; TGCT cis rs4383453 0.539 rs4677886 chr3:123100196 A/G cg04890266 chr3:123102914 ADCY5 -0.5 -8.19 -0.59 2.68e-13 Gestational age at birth (maternal effect); TGCT cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs3806843 0.868 rs2531342 chr5:140130612 C/T cg19875535 chr5:140030758 IK -0.36 -5.97 -0.47 2.32e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9325144 0.624 rs7979541 chr12:39129679 T/C cg13010199 chr12:38710504 ALG10B -0.52 -4.68 -0.39 7.29e-6 Morning vs. evening chronotype; TGCT cis rs9443189 0.570 rs72888705 chr6:76403114 A/G cg01950844 chr6:76311363 SENP6 1.0 6.24 0.49 6.35e-9 Prostate cancer; TGCT cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg18402987 chr7:1209562 NA 0.39 4.99 0.41 1.97e-6 Longevity;Endometriosis; TGCT cis rs832540 0.898 rs252890 chr5:56226410 T/C cg24531977 chr5:56204891 C5orf35 -0.49 -5.03 -0.41 1.66e-6 Coronary artery disease; TGCT cis rs12477438 0.520 rs6542864 chr2:99725223 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs35883536 0.528 rs1542837 chr1:101029768 T/C cg10298815 chr1:101004474 GPR88 0.25 4.69 0.39 7.06e-6 Monocyte count; TGCT cis rs9926296 0.568 rs1230 chr16:89804855 A/G cg03388025 chr16:89894329 SPIRE2 -0.49 -8.46 -0.6 6.36e-14 Vitiligo; TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.09 -16.13 -0.82 3.1e-32 Prudent dietary pattern; TGCT cis rs7474896 0.515 rs594594 chr10:38307723 A/G cg13720705 chr10:37990370 NA -0.37 -4.68 -0.39 7.35e-6 Obesity (extreme); TGCT cis rs12541335 0.507 rs9644047 chr8:22158670 T/A cg18135555 chr8:22132992 PIWIL2 0.28 5.51 0.44 1.98e-7 Hypertriglyceridemia; TGCT cis rs10927875 0.864 rs1976402 chr1:16143779 G/A cg21385522 chr1:16154831 NA -0.89 -11.09 -0.71 2.88e-20 Dilated cardiomyopathy; TGCT cis rs5769707 0.837 rs5770599 chr22:50019981 C/G cg05373962 chr22:49881684 NA -0.27 -5.14 -0.42 1.03e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7267979 0.932 rs6115214 chr20:25557426 C/T cg03522245 chr20:25566470 NINL -0.58 -6.24 -0.49 6.39e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7809950 1.000 rs7786801 chr7:107085889 C/T cg23024343 chr7:107201750 COG5 -0.35 -5.54 -0.45 1.71e-7 Coronary artery disease; TGCT cis rs7833790 0.685 rs13255262 chr8:82728024 T/G cg27398817 chr8:82754497 SNX16 -0.67 -5.34 -0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs11809207 0.522 rs3762459 chr1:26494886 C/G cg24519413 chr1:26490540 NA 0.22 4.57 0.38 1.18e-5 Height; TGCT cis rs114540395 0.858 rs17767748 chr10:103285900 A/G cg22630918 chr10:102748988 C10orf2 -0.43 -4.51 -0.38 1.46e-5 Schizophrenia; TGCT cis rs7584330 0.737 rs61212490 chr2:238365230 T/C cg14458575 chr2:238380390 NA 0.51 8.14 0.59 3.53e-13 Prostate cancer; TGCT cis rs9527 0.590 rs2281877 chr10:104866062 C/T cg04362960 chr10:104952993 NT5C2 0.7 5.88 0.47 3.57e-8 Arsenic metabolism; TGCT cis rs7666738 0.830 rs13116691 chr4:98929771 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 0.900 rs12650220 chr4:17595365 A/T cg10189774 chr4:17578691 LAP3 0.69 5.85 0.47 4.09e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7829975 0.846 rs6601724 chr8:8544872 C/T cg08975724 chr8:8085496 FLJ10661 -0.53 -4.71 -0.39 6.49e-6 Mood instability; TGCT cis rs2050392 0.894 rs2480277 chr10:30703513 G/T cg13289132 chr10:30722225 MAP3K8 0.37 4.51 0.38 1.46e-5 Inflammatory bowel disease; TGCT cis rs9486719 1.000 rs4078038 chr6:96904366 A/G cg06623918 chr6:96969491 KIAA0776 -0.99 -8.79 -0.62 1.03e-14 Migraine;Coronary artery disease; TGCT cis rs13108904 0.901 rs1316393 chr4:1315619 A/G cg03303774 chr4:1407052 NA -0.34 -5.43 -0.44 2.91e-7 Obesity-related traits; TGCT cis rs61884328 0.852 rs57964319 chr11:47146599 C/T cg13308137 chr11:47528955 CUGBP1 0.38 4.47 0.37 1.76e-5 Total body bone mineral density (age over 60); TGCT cis rs79149102 0.579 rs12594117 chr15:75323648 C/G cg09165964 chr15:75287851 SCAMP5 -1.07 -5.81 -0.46 4.93e-8 Lung cancer; TGCT cis rs12142240 0.731 rs12385693 chr1:46818921 A/C cg07811940 chr1:46828259 NSUN4 0.27 4.56 0.38 1.2e-5 Menopause (age at onset); TGCT cis rs2067615 0.579 rs1922435 chr12:107082455 A/G cg15890332 chr12:107067104 RFX4 0.3 5.91 0.47 3.15e-8 Heart rate; TGCT cis rs1153858 1.000 rs4775895 chr15:45617957 T/A cg26924012 chr15:45694286 SPATA5L1 1.05 13.95 0.78 3.56e-27 Homoarginine levels; TGCT cis rs11792861 0.816 rs7021366 chr9:111727670 C/G cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 4.96 0.41 2.24e-6 Menarche (age at onset); TGCT cis rs2228479 1.000 rs4257207 chr16:89947861 T/A cg06558623 chr16:89946397 TCF25 0.57 6.46 0.5 2.15e-9 Skin colour saturation; TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg24503407 chr1:205819492 PM20D1 0.68 11.04 0.7 3.64e-20 Menarche (age at onset); TGCT cis rs2239547 0.525 rs2246556 chr3:53027983 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.61 0.38 9.77e-6 Schizophrenia; TGCT cis rs7666738 0.791 rs28858828 chr4:98950442 C/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs9467711 1.000 rs6923139 chr6:26313348 C/T cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs4665809 0.590 rs2033317 chr2:26477650 G/A cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs6940638 1.000 rs12204280 chr6:27033104 T/C cg26531700 chr6:26746687 NA -0.6 -4.63 -0.38 9.25e-6 Intelligence (multi-trait analysis); TGCT trans rs13270892 0.556 rs57487396 chr8:20469493 C/T cg14551562 chr9:130461838 NA -0.89 -6.75 -0.52 5.19e-10 Daytime sleep phenotypes; TGCT cis rs4951018 0.821 rs7529037 chr1:205637501 C/G cg14159672 chr1:205819179 PM20D1 -0.39 -4.59 -0.38 1.07e-5 Prostate-specific antigen levels; TGCT cis rs17401966 0.931 rs3737155 chr1:10459779 G/A cg19773385 chr1:10388646 KIF1B -0.23 -5.42 -0.44 2.97e-7 Hepatocellular carcinoma; TGCT cis rs873946 0.504 rs3793681 chr10:134564451 T/C cg05985448 chr10:134359359 INPP5A 0.22 4.75 0.39 5.54e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs10927875 0.632 rs6677321 chr1:16149301 A/C cg14742211 chr1:16348397 CLCNKA -0.2 -4.79 -0.39 4.75e-6 Dilated cardiomyopathy; TGCT cis rs1008375 0.686 rs34338142 chr4:17626174 T/A cg10189774 chr4:17578691 LAP3 0.67 5.65 0.45 1.02e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1729951 0.575 rs1654926 chr3:136709924 G/A cg12473912 chr3:136751656 NA 0.39 6.33 0.49 4.01e-9 Neuroticism; TGCT cis rs17384381 0.953 rs12120551 chr1:85810903 T/C cg16011679 chr1:85725395 C1orf52 0.84 6.5 0.5 1.74e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs11971779 0.680 rs10229358 chr7:139052545 C/T cg07862535 chr7:139043722 LUC7L2 -0.57 -4.52 -0.38 1.42e-5 Diisocyanate-induced asthma; TGCT cis rs2334880 0.678 rs12922830 chr16:71447270 C/T cg06353428 chr16:71660113 MARVELD3 -0.96 -6.35 -0.5 3.66e-9 Malaria; TGCT cis rs9399137 0.507 rs11154791 chr6:135379148 A/G cg24558204 chr6:135376177 HBS1L 0.47 4.73 0.39 5.98e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs42648 0.748 rs10226014 chr7:89902533 C/T cg25739043 chr7:89950458 NA 0.62 6.12 0.48 1.15e-8 Homocysteine levels; TGCT cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg02353165 chr6:42928485 GNMT 0.95 9.5 0.65 2.01e-16 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7731657 0.537 rs10073487 chr5:130373397 G/A cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs6089829 0.962 rs6062780 chr20:61666648 T/C cg02380750 chr20:61661411 NA 0.33 5.96 0.47 2.4e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs11148252 0.532 rs9536185 chr13:53179801 G/A cg02158880 chr13:53174818 NA 0.49 5.66 0.45 9.75e-8 Lewy body disease; TGCT cis rs7618915 0.501 rs2159644 chr3:52774530 C/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.54 -5.11 -0.42 1.21e-6 Bipolar disorder; TGCT cis rs61990749 0.597 rs176980 chr14:78198449 C/G cg02301378 chr14:78227641 SNW1;C14orf178 -0.62 -4.58 -0.38 1.13e-5 Fibroblast growth factor basic levels; TGCT cis rs873946 0.586 rs12783078 chr10:134569706 C/T cg18305652 chr10:134549665 INPP5A 0.35 6.01 0.48 1.89e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9467773 0.620 rs2101581 chr6:26622769 G/T cg15659132 chr6:26577336 NA 0.86 11.08 0.71 3.01e-20 Intelligence (multi-trait analysis); TGCT cis rs651907 0.557 rs7645391 chr3:101361506 C/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.9 10.75 0.69 1.88e-19 Colorectal cancer; TGCT cis rs3820068 0.608 rs12091326 chr1:16048005 A/G cg17385448 chr1:15911702 AGMAT 0.36 4.76 0.39 5.21e-6 Systolic blood pressure; TGCT cis rs79387448 0.564 rs77375846 chr2:103155075 T/C cg09003973 chr2:102972529 NA 1.15 6.67 0.51 7.66e-10 Gut microbiota (bacterial taxa); TGCT cis rs6582630 0.555 rs10880421 chr12:38423015 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.76 0.57 2.69e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs35883536 0.967 rs4908085 chr1:101087901 C/G cg06223162 chr1:101003688 GPR88 0.29 4.61 0.38 9.73e-6 Monocyte count; TGCT cis rs12541335 0.639 rs6993855 chr8:22163797 A/G cg02463440 chr8:22132932 PIWIL2 0.24 4.69 0.39 7.2e-6 Hypertriglyceridemia; TGCT cis rs7727544 0.716 rs11949055 chr5:131576737 T/C cg24060327 chr5:131705240 SLC22A5 -0.56 -5.5 -0.44 2.06e-7 Blood metabolite levels; TGCT cis rs12188164 1.000 rs72717411 chr5:429124 C/G cg26850624 chr5:429559 AHRR -0.2 -4.81 -0.4 4.22e-6 Cystic fibrosis severity; TGCT cis rs8180040 0.726 rs4682842 chr3:46982773 C/G cg27129171 chr3:47204927 SETD2 -0.71 -8.76 -0.62 1.25e-14 Colorectal cancer; TGCT cis rs9419702 0.639 rs4367873 chr10:133533485 C/T cg20568497 chr10:133558893 NA 0.45 4.73 0.39 6e-6 Survival in rectal cancer; TGCT cis rs6785206 0.892 rs6793907 chr3:128391626 A/G cg14476212 chr3:127535191 MGLL -0.67 -4.73 -0.39 6.02e-6 Lymphocyte percentage of white cells; TGCT cis rs13242816 1.000 rs56180538 chr7:116079711 C/T cg02799643 chr7:116139180 CAV2 -0.44 -5.15 -0.42 9.76e-7 P wave duration; TGCT cis rs6688613 1.000 rs12569084 chr1:166943352 T/C cg07049167 chr1:166818506 POGK 0.22 4.55 0.38 1.25e-5 Refractive astigmatism; TGCT cis rs7590720 0.819 rs12467676 chr2:216895736 T/G cg12620499 chr2:216877984 MREG 0.9 10.43 0.68 1.17e-18 Alcohol dependence; TGCT cis rs11105298 0.891 rs11105318 chr12:89926658 C/T cg00757033 chr12:89920650 WDR51B 0.31 5.04 0.41 1.57e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs11249608 0.750 rs6891216 chr5:178447026 G/C cg01312482 chr5:178451176 ZNF879 -0.55 -5.41 -0.44 3.08e-7 Pubertal anthropometrics; TGCT cis rs12681288 0.550 rs7000482 chr8:958380 T/C cg04851639 chr8:1020857 NA -0.27 -4.45 -0.37 1.85e-5 Schizophrenia; TGCT cis rs9926296 0.643 rs12596429 chr16:89841374 T/C cg08627397 chr16:89984028 MC1R -0.3 -4.66 -0.39 8.13e-6 Vitiligo; TGCT cis rs13217239 0.646 rs10456351 chr6:26986792 C/T cg07220782 chr6:26987966 LOC100270746;C6orf41 0.4 4.47 0.37 1.76e-5 Schizophrenia; TGCT cis rs877529 0.647 rs139395 chr22:39538433 T/C cg18708252 chr22:39545030 CBX7 -0.35 -5.34 -0.43 4.28e-7 Multiple myeloma; TGCT cis rs801193 0.967 rs2707841 chr7:66157020 A/G cg00343986 chr7:65444356 GUSB 0.22 5.01 0.41 1.84e-6 Aortic root size; TGCT cis rs3733346 0.590 rs6848199 chr4:940838 C/T cg22718636 chr4:961658 DGKQ 0.46 4.47 0.37 1.77e-5 Sjögren's syndrome; TGCT cis rs7246657 0.943 rs12981532 chr19:37889280 G/A cg18154014 chr19:37997991 ZNF793 0.95 6.63 0.51 9.39e-10 Coronary artery calcification; TGCT cis rs7666738 0.791 rs1896155 chr4:99020948 C/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3091242 0.836 rs35346083 chr1:25788425 C/A cg00786635 chr1:25594202 NA -0.55 -5.67 -0.45 9.46e-8 Erythrocyte sedimentation rate; TGCT cis rs7666738 0.830 rs35938349 chr4:98974998 T/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12142240 0.698 rs10158572 chr1:46822440 G/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs7917772 0.582 rs7906115 chr10:104327164 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4563143 0.592 rs12151001 chr19:29283386 C/G cg14983838 chr19:29218262 NA 0.86 7.07 0.54 9.71e-11 Methadone dose in opioid dependence; TGCT cis rs916888 0.687 rs199456 chr17:44797919 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 -0.61 -5.23 -0.42 7.12e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6951245 1.000 rs11763835 chr7:1094513 A/G cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs8179 0.648 rs42036 chr7:92241451 C/G cg15732164 chr7:92237376 CDK6 -0.3 -5.34 -0.43 4.22e-7 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs4808199 0.947 rs1465695 chr19:19588546 A/C cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.2 0.42 8.14e-7 Nonalcoholic fatty liver disease; TGCT cis rs9467711 0.606 rs9348709 chr6:26360311 G/A cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7524258 0.868 rs10779678 chr1:7300573 A/G cg04342483 chr1:7259290 CAMTA1 -0.3 -4.48 -0.37 1.7e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs1862618 0.853 rs860580 chr5:56149429 G/T cg24531977 chr5:56204891 C5orf35 0.75 7.52 0.56 9.46e-12 Initial pursuit acceleration; TGCT cis rs2486288 0.656 rs8037583 chr15:45546378 A/G cg26924012 chr15:45694286 SPATA5L1 -0.71 -7.39 -0.55 1.91e-11 Glomerular filtration rate; TGCT cis rs7635838 0.892 rs9310381 chr3:11458466 A/G cg00170343 chr3:11313890 ATG7 0.65 6.15 0.48 9.98e-9 HDL cholesterol; TGCT cis rs2708977 0.609 rs670498 chr2:97090227 A/G cg01950434 chr2:97203154 ARID5A -0.61 -5.17 -0.42 9.02e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs7786808 0.615 rs4909212 chr7:158197037 G/T cg01191920 chr7:158217561 PTPRN2 -0.41 -6.14 -0.48 1.03e-8 Obesity-related traits; TGCT cis rs2032447 0.736 rs115810 chr6:25975883 G/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.94 10.14 0.67 5.79e-18 Intelligence (multi-trait analysis); TGCT cis rs939574 0.858 rs2891733 chr2:220135208 A/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.06 6.67 0.51 7.65e-10 Platelet distribution width; TGCT cis rs9577381 0.628 rs9577380 chr13:112575568 A/G cg11336860 chr13:112575966 NA -0.28 -4.45 -0.37 1.87e-5 Axial length; TGCT cis rs9393777 0.513 rs9368451 chr6:26654333 A/G cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs9393707 chr6:26362486 T/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs13108904 0.870 rs3775094 chr4:1238859 G/A cg03303774 chr4:1407052 NA 0.28 4.57 0.38 1.16e-5 Obesity-related traits; TGCT cis rs2016266 0.964 rs1110720 chr12:53682326 G/A cg16917193 chr12:54089295 NA 0.67 5.27 0.43 5.83e-7 Bone mineral density (spine);Bone mineral density; TGCT cis rs2153535 0.580 rs7775909 chr6:8477778 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs950027 0.549 rs1719250 chr15:45609773 A/G cg26924012 chr15:45694286 SPATA5L1 0.78 8.49 0.61 5.48e-14 Response to fenofibrate (adiponectin levels); TGCT trans rs10203711 1.000 rs10207724 chr2:239566705 G/C cg16021909 chr1:248021091 TRIM58 -0.66 -6.66 -0.51 7.94e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9467773 0.620 rs1027204 chr6:26639613 T/C cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT trans rs9364554 0.506 rs3125055 chr6:160736787 A/T cg01534613 chr7:96337050 SHFM1 0.54 6.66 0.51 8e-10 Prostate cancer (SNP x SNP interaction);Prostate cancer; TGCT cis rs13108904 0.934 rs13125842 chr4:1280947 G/A cg03303774 chr4:1407052 NA 0.31 4.93 0.4 2.58e-6 Obesity-related traits; TGCT cis rs11264213 0.901 rs72661644 chr1:36453894 G/A cg27506609 chr1:36549197 TEKT2 0.41 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs4851266 0.933 rs6709656 chr2:100806719 A/G cg07810366 chr2:100720526 AFF3 -0.39 -5.69 -0.46 8.49e-8 Educational attainment; TGCT cis rs2658782 1.000 rs2605582 chr11:93163799 C/T cg15737290 chr11:93063684 CCDC67 0.78 5.51 0.44 1.94e-7 Pulmonary function decline; TGCT cis rs3125734 0.719 rs3852410 chr10:64037563 A/G cg09941381 chr10:64027924 RTKN2 0.33 4.67 0.39 7.61e-6 Rheumatoid arthritis; TGCT cis rs2502731 1.000 rs2502731 chr9:130976557 A/G cg09976142 chr9:130955436 CIZ1 -0.45 -5.3 -0.43 5.21e-7 Attention deficit hyperactivity disorder; TGCT cis rs2921036 0.505 rs35190619 chr8:8361823 A/C cg06636001 chr8:8085503 FLJ10661 -0.64 -5.72 -0.46 7.43e-8 Neuroticism; TGCT cis rs2338224 1.000 rs10043295 chr5:71743024 C/G cg01187920 chr5:71015162 CARTPT -0.53 -4.61 -0.38 9.68e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;White blood cell count;Neutrophil count;Granulocyte count;Myeloid white cell count; TGCT cis rs7267979 1.000 rs6138575 chr20:25438952 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs9951602 1.000 rs9949784 chr18:76649994 A/G cg02800362 chr5:177631904 HNRNPAB 1.02 7.23 0.54 4.4e-11 Obesity-related traits; TGCT cis rs60843830 0.964 rs17713879 chr2:254215 G/A cg25945732 chr2:264204 ACP1;SH3YL1 0.7 7.03 0.53 1.22e-10 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs56104184 0.775 rs73061694 chr19:49399978 T/C cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs13191362 0.935 rs13193473 chr6:162966852 C/A cg21926612 chr6:163149169 PACRG;PARK2 0.66 5.11 0.42 1.17e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4886920 0.666 rs12591307 chr15:78081529 C/T cg25212270 chr15:78015279 NA -0.23 -4.86 -0.4 3.45e-6 Neuroticism; TGCT cis rs10927875 0.793 rs1763619 chr1:16326935 A/G cg21385522 chr1:16154831 NA 0.64 6.9 0.53 2.33e-10 Dilated cardiomyopathy; TGCT cis rs10540 1.000 rs35068485 chr11:466032 A/T cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs727505 0.721 rs67817822 chr7:124769572 A/G cg23710748 chr7:124431027 NA -0.25 -4.44 -0.37 1.97e-5 Lewy body disease; TGCT cis rs524281 0.861 rs10791854 chr11:65963543 A/T cg00563793 chr11:65837595 PACS1 0.53 4.67 0.39 7.6e-6 Electroencephalogram traits; TGCT cis rs7937682 0.889 rs479667 chr11:111484034 C/T cg09085632 chr11:111637200 PPP2R1B -1.05 -11.35 -0.71 6.63e-21 Primary sclerosing cholangitis; TGCT cis rs5769765 0.704 rs138837 chr22:50180714 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.93 -8.67 -0.61 2.04e-14 Schizophrenia; TGCT cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg16423285 chr20:60520624 NA -0.69 -7.11 -0.54 8.23e-11 Body mass index; TGCT cis rs1577917 0.761 rs117452258 chr6:86554211 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.66 -5.29 -0.43 5.34e-7 Response to antipsychotic treatment; TGCT cis rs72843506 0.722 rs75226250 chr17:20132317 G/A cg18979559 chr17:20280153 CCDC144C -0.64 -4.84 -0.4 3.71e-6 Schizophrenia; TGCT cis rs10504229 0.683 rs7843919 chr8:58130792 T/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs13148324 chr4:98833616 G/A cg05340658 chr4:99064831 C4orf37 0.53 6.18 0.49 8.5e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9303401 0.614 rs12948536 chr17:56580413 G/T cg02118635 chr17:56770003 RAD51C;TEX14 0.63 6.36 0.5 3.54e-9 Cognitive test performance; TGCT cis rs78487399 0.519 rs11124929 chr2:43582103 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.08 -0.48 1.36e-8 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT trans rs8048207 1.000 rs4567699 chr16:61792663 C/T cg12718502 chr12:2999424 TULP3 -0.71 -6.8 -0.52 4.01e-10 Non-small cell lung cancer; TGCT cis rs1865760 0.929 rs2876693 chr6:25954434 C/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.25 0.49 6.04e-9 Height; TGCT cis rs11711311 1.000 rs12736 chr3:113530211 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs6484504 0.576 rs208071 chr11:31144996 C/T cg26647111 chr11:31128758 NA -0.33 -4.55 -0.38 1.27e-5 Red blood cell count; TGCT cis rs873946 0.586 rs57431984 chr10:134567697 C/T cg18305652 chr10:134549665 INPP5A 0.35 5.94 0.47 2.73e-8 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs981844 1.000 rs1116636 chr4:154657151 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs586688 0.696 rs1256457 chr1:201659739 T/C cg07139329 chr1:201708558 NAV1 -0.55 -5.47 -0.44 2.37e-7 Obesity-related traits; TGCT cis rs7811142 0.830 rs76798830 chr7:99952828 C/T cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs12484776 0.729 rs67465697 chr22:40531645 A/G cg07138101 chr22:40742427 ADSL 0.61 4.6 0.38 1.01e-5 Uterine fibroids; TGCT cis rs7178572 0.568 rs12912050 chr15:77689423 C/T cg22256960 chr15:77711686 NA -0.88 -9.16 -0.64 1.32e-15 Type 2 diabetes; TGCT cis rs367615 0.660 rs10477972 chr5:108831951 C/A cg17395555 chr5:108820864 NA 0.31 5.9 0.47 3.17e-8 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7829975 0.572 rs7005000 chr8:8796602 A/G cg15556689 chr8:8085844 FLJ10661 -0.69 -6.25 -0.49 5.93e-9 Mood instability; TGCT cis rs7811142 1.000 rs113738841 chr7:100081306 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs919433 0.647 rs1979239 chr2:198498316 T/G cg00792783 chr2:198669748 PLCL1 0.56 5.03 0.41 1.68e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs769267 0.930 rs10282 chr19:19619317 T/C cg03709012 chr19:19516395 GATAD2A 0.75 6.16 0.48 9.21e-9 Tonsillectomy; TGCT cis rs7772486 0.686 rs9403741 chr6:146030548 G/A cg23711669 chr6:146136114 FBXO30 -0.88 -9.77 -0.66 4.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 0.966 rs454723 chr20:25438928 G/C cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6998277 0.830 rs17186961 chr8:103630028 G/A cg10187029 chr8:103597600 NA 0.5 7.42 0.55 1.66e-11 Migraine; TGCT cis rs9291683 0.588 rs13133766 chr4:10019732 C/T cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Bone mineral density; TGCT cis rs3087591 1.000 rs2012988 chr17:29547296 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 7.18 0.54 5.72e-11 Hip circumference; TGCT cis rs7089973 0.604 rs2181563 chr10:116604344 T/C cg03647239 chr10:116582469 FAM160B1 0.6 5.73 0.46 7.18e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs2033711 0.870 rs1465789 chr19:58946056 C/T cg13877915 chr19:58951672 ZNF132 0.9 11.15 0.71 2.05e-20 Uric acid clearance; TGCT cis rs11711311 1.000 rs3732793 chr3:113442198 C/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -6.84 -0.52 3.17e-10 IgG glycosylation; TGCT cis rs2842992 0.830 rs2025189 chr6:160137518 C/T cg11366901 chr6:160182831 ACAT2 1.01 6.74 0.52 5.42e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs2885056 0.783 rs73007347 chr19:10650649 C/T cg04833646 chr19:10679720 CDKN2D 0.92 8.19 0.59 2.65e-13 Red cell distribution width; TGCT cis rs986417 0.818 rs4278669 chr14:60982075 T/C cg27398547 chr14:60952738 C14orf39 1.5 10.38 0.68 1.54e-18 Gut microbiota (bacterial taxa); TGCT cis rs11107903 1.000 rs11107904 chr12:95515719 T/C cg10621809 chr12:95840313 NA 0.67 4.52 0.38 1.41e-5 Coronary artery disease; TGCT cis rs6920965 0.509 rs654213 chr6:126149127 C/T cg05901451 chr6:126070800 HEY2 0.54 4.82 0.4 4.1e-6 High light scatter reticulocyte count; TGCT cis rs35264875 0.851 rs72930631 chr11:68867835 T/C cg02660097 chr11:68866761 NA 0.32 5.06 0.41 1.48e-6 Blond vs. brown hair color; TGCT cis rs4665809 0.531 rs34081866 chr2:26475940 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg00814883 chr7:100076585 TSC22D4 -0.91 -9.41 -0.65 3.39e-16 Platelet count; TGCT cis rs9372498 0.536 rs62421539 chr6:118730559 C/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.03e-6 Diastolic blood pressure; TGCT cis rs9611565 0.512 rs4822052 chr22:42193741 G/A cg13695892 chr22:41940480 POLR3H -0.83 -8.2 -0.59 2.54e-13 Vitiligo; TGCT cis rs3806843 0.576 rs246063 chr5:140324492 T/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs921968 0.715 rs62182125 chr2:219274142 G/A cg02176678 chr2:219576539 TTLL4 0.37 5.34 0.43 4.28e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs782590 0.559 rs12617719 chr2:55915826 G/C cg18811423 chr2:55921094 PNPT1 -0.68 -7.6 -0.56 6.39e-12 Metabolic syndrome; TGCT cis rs67311347 1.000 rs9833430 chr3:40459043 C/T cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT trans rs7618501 0.602 rs2301166 chr3:50148305 C/G cg21659725 chr3:3221576 CRBN -0.73 -8.46 -0.6 6.21e-14 Intelligence (multi-trait analysis); TGCT cis rs4689388 0.856 rs10016157 chr4:6294414 T/C cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4478858 0.735 rs1566964 chr1:31792794 C/A cg07478791 chr1:31886160 SERINC2 -0.51 -4.94 -0.41 2.47e-6 Alcohol dependence; TGCT cis rs11677203 1.000 rs12990104 chr2:12564429 G/A cg00419568 chr2:11919532 LPIN1 -0.2 -4.55 -0.38 1.26e-5 Electroencephalogram traits; TGCT cis rs8031584 0.736 rs11635775 chr15:31160640 A/G cg08109568 chr15:31115862 NA -0.39 -5.18 -0.42 8.86e-7 Huntington's disease progression; TGCT cis rs1008375 1.000 rs555 chr4:17625658 A/G cg18681998 chr4:17616180 MED28 1.0 11.31 0.71 8.26e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9318086 0.648 rs78881146 chr13:24468704 G/A cg25267304 chr13:24462978 PCOTH;MIPEP 0.83 9.04 0.63 2.62e-15 Myopia (pathological); TGCT cis rs4727027 0.704 rs7787753 chr7:148901779 A/T cg23583168 chr7:148888333 NA -0.81 -10.92 -0.7 7.37e-20 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT trans rs72737821 0.714 rs17385947 chr1:98655574 C/A cg14575559 chr19:18111766 ARRDC2 0.61 6.69 0.51 6.93e-10 Cognitive ability;Cognitive ability (multi-trait analysis); TGCT cis rs67311347 1.000 rs28434528 chr3:40484893 A/G cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs74233809 1.000 rs77602510 chr10:104682602 G/A cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs1964356 0.967 rs17701675 chr8:8850633 A/G cg06636001 chr8:8085503 FLJ10661 -0.72 -6.29 -0.49 4.95e-9 Mean corpuscular volume; TGCT cis rs2236918 0.710 rs2797603 chr1:242029027 T/G cg04158730 chr1:242011433 EXO1 0.56 5.2 0.42 8.05e-7 Menopause (age at onset); TGCT cis rs1023500 0.573 rs133378 chr22:42467695 G/C cg15557168 chr22:42548783 NA -0.23 -5.77 -0.46 6e-8 Schizophrenia; TGCT cis rs6866344 0.570 rs1132338 chr5:178139442 T/G cg10224037 chr5:178157518 ZNF354A 0.98 9.68 0.66 7.49e-17 Neutrophil percentage of white cells; TGCT cis rs9486719 0.901 rs13206547 chr6:97006942 T/C cg18709589 chr6:96969512 KIAA0776 -0.77 -5.47 -0.44 2.38e-7 Migraine;Coronary artery disease; TGCT cis rs644799 1.000 rs505220 chr11:95563228 T/G cg25622487 chr11:95524042 FAM76B;CEP57 0.82 8.63 0.61 2.52e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs875971 0.862 rs6971059 chr7:66067032 A/G cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.89e-6 Aortic root size; TGCT cis rs13242816 1.000 rs62469031 chr7:116195841 A/G cg16553024 chr7:116138462 CAV2 -0.43 -5.19 -0.42 8.16e-7 P wave duration; TGCT cis rs7223966 1.000 rs8067431 chr17:61817048 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.57 4.57 0.38 1.16e-5 Hip circumference adjusted for BMI;Body mass index; TGCT trans rs459571 0.959 rs416390 chr9:136908549 C/G cg09836344 chr4:1243392 C4orf42;CTBP1 0.73 7.95 0.58 9.76e-13 Platelet distribution width; TGCT cis rs5769765 0.955 rs9616368 chr22:50303533 C/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.17 -11.76 -0.73 6.61e-22 Schizophrenia; TGCT cis rs1894292 0.527 rs1894293 chr4:74352022 G/A cg05868023 chr4:75230803 EREG 0.51 4.5 0.37 1.56e-5 Prostate cancer; TGCT cis rs1497406 0.744 rs924203 chr1:16511539 G/T cg20430773 chr1:16534157 ARHGEF19 0.55 6.25 0.49 6e-9 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10114408 0.959 rs7033563 chr9:96663499 T/C cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7811142 1.000 rs73161759 chr7:100009994 T/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg17554472 chr22:41940697 POLR3H -0.47 -4.86 -0.4 3.54e-6 Vitiligo; TGCT cis rs295140 0.605 rs10931893 chr2:201114652 A/G cg23649088 chr2:200775458 C2orf69 -0.3 -5.03 -0.41 1.7e-6 QT interval; TGCT cis rs1534166 0.647 rs7355929 chr3:133514190 C/T cg08048268 chr3:133502702 NA 0.45 5.47 0.44 2.34e-7 Alcohol consumption (transferrin glycosylation); TGCT cis rs9549367 0.789 rs9549361 chr13:113898329 C/T cg00898013 chr13:113819073 PROZ 0.4 4.95 0.41 2.36e-6 Platelet distribution width; TGCT cis rs9921222 0.656 rs12719801 chr16:381141 C/T cg10349874 chr16:420996 TMEM8A;MRPL28 -0.26 -4.63 -0.38 9.21e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs7567389 0.600 rs7590030 chr2:128055967 G/A cg09760422 chr2:128146352 NA -0.39 -5.18 -0.42 8.76e-7 Self-rated health; TGCT cis rs6951245 0.872 rs112309216 chr7:1100296 A/T cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs763121 0.819 rs5750629 chr22:38985065 T/C cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs7043114 0.507 rs6479420 chr9:95116406 T/C cg13798575 chr9:95087839 CENPP;NOL8 -0.55 -5.56 -0.45 1.61e-7 Height; TGCT cis rs2836974 0.863 rs8128026 chr21:40533702 T/C cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.71e-9 Cognitive function; TGCT cis rs6088580 0.634 rs6058051 chr20:33044862 G/A cg06115741 chr20:33292138 TP53INP2 0.55 4.68 0.39 7.39e-6 Glomerular filtration rate (creatinine); TGCT cis rs9399135 0.967 rs9389256 chr6:135331254 A/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs1552244 1.000 rs33917318 chr3:10067797 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9790314 0.846 rs6441371 chr3:161008727 C/A cg03342759 chr3:160939853 NMD3 -0.42 -4.51 -0.38 1.5e-5 Morning vs. evening chronotype; TGCT cis rs6121246 0.647 rs6088855 chr20:30225792 C/T cg21427119 chr20:30132790 HM13 -0.35 -4.74 -0.39 5.73e-6 Mean corpuscular hemoglobin; TGCT cis rs10197940 0.578 rs2045025 chr2:152317531 T/C cg19508488 chr2:152266495 RIF1 0.61 5.12 0.42 1.12e-6 Lung cancer; TGCT cis rs909674 0.865 rs5757682 chr22:39848259 T/G cg01416388 chr22:39784598 NA -0.69 -6.28 -0.49 5.3e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs941873 0.868 rs7332 chr10:81114060 G/A cg09469691 chr10:81107165 PPIF 0.64 6.53 0.51 1.5e-9 Height; TGCT cis rs2932538 0.922 rs2932535 chr1:113201412 G/C cg22162597 chr1:113214053 CAPZA1 -0.27 -5.98 -0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7255045 0.752 rs2242512 chr19:12975599 G/A cg06537894 chr19:12978706 MAST1 -0.49 -4.48 -0.37 1.69e-5 Mean corpuscular volume; TGCT cis rs35828350 1 rs35828350 chr15:85355841 G/A cg12863693 chr15:85201151 NMB 0.41 4.92 0.4 2.65e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4409675 0.576 rs12062621 chr1:28230404 A/G cg23691781 chr1:28212827 C1orf38 0.25 5.38 0.43 3.59e-7 Corneal astigmatism; TGCT cis rs2956278 0.717 rs986802 chr12:84683978 T/C cg25678815 chr12:85673915 ALX1 -0.53 -4.76 -0.39 5.4e-6 Depressive symptoms;Depressive symptoms (multi-trait analysis); TGCT trans rs7618501 1.000 rs7374277 chr3:49784777 T/C cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs1129187 0.719 rs3805953 chr6:42936900 C/T cg10862848 chr6:42927986 GNMT -0.4 -4.97 -0.41 2.14e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs13242816 1.000 rs7796429 chr7:116144369 T/C cg02799643 chr7:116139180 CAV2 -0.42 -5.46 -0.44 2.45e-7 P wave duration; TGCT cis rs881375 0.678 rs3761846 chr9:123689597 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.4 4.64 0.38 8.89e-6 Rheumatoid arthritis; TGCT cis rs2486288 0.656 rs11631021 chr15:45556829 A/G cg26924012 chr15:45694286 SPATA5L1 -0.81 -8.67 -0.61 1.95e-14 Glomerular filtration rate; TGCT cis rs12477438 0.765 rs12612688 chr2:99613091 C/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.54 -4.66 -0.39 8.04e-6 Chronic sinus infection; TGCT cis rs514406 0.861 rs551435 chr1:53260537 G/T cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg25767906 chr1:53392781 SCP2 -0.61 -7.35 -0.55 2.37e-11 Monocyte count; TGCT cis rs17473412 1.000 rs6595439 chr5:122692786 G/C cg15125798 chr5:122621645 NA -0.54 -4.96 -0.41 2.28e-6 Total body bone mineral density; TGCT cis rs8054556 0.656 rs4420550 chr16:29938820 A/G cg26859862 chr16:30389551 SEPT1 -0.54 -4.61 -0.38 9.9e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs694739 0.628 rs508168 chr11:64135435 G/A cg02228329 chr11:64053129 BAD;GPR137 0.69 6.78 0.52 4.25e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs5769707 0.872 rs5770604 chr22:50030672 G/A cg05373962 chr22:49881684 NA -0.29 -5.5 -0.44 2.06e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6543140 0.964 rs6761350 chr2:103030776 A/G cg09003973 chr2:102972529 NA 0.59 4.95 0.41 2.39e-6 Blood protein levels; TGCT cis rs10504229 0.728 rs17216187 chr8:58158778 G/T cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs7731657 0.537 rs13355837 chr5:130360537 C/T cg08523029 chr5:130500466 HINT1 -0.6 -4.91 -0.4 2.79e-6 Fasting plasma glucose; TGCT cis rs9534288 0.659 rs9534314 chr13:46654844 A/G cg15192986 chr13:46630673 CPB2 -0.53 -6.39 -0.5 3.01e-9 Blood protein levels; TGCT cis rs7655441 1.000 rs11098957 chr4:80880510 C/T cg02241357 chr4:80885279 ANTXR2 -0.23 -4.46 -0.37 1.81e-5 Neutrophil percentage of white cells; TGCT cis rs1129187 0.837 rs3763236 chr6:42902508 C/T cg17345569 chr6:42928274 GNMT 0.47 5.41 0.44 3.15e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9677476 0.516 rs2303350 chr2:232030555 G/A cg27665808 chr2:232055229 NA 0.35 4.43 0.37 2.01e-5 Food antigen IgG levels; TGCT cis rs2580764 0.678 rs2255112 chr2:55200800 T/G cg09592903 chr2:55203963 RTN4 0.24 5.4 0.44 3.33e-7 Mean platelet volume; TGCT cis rs669446 0.591 rs483679 chr1:44108119 T/A cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs12908161 0.515 rs12907646 chr15:85403496 G/A cg11189052 chr15:85197271 WDR73 0.65 4.81 0.4 4.3e-6 Schizophrenia; TGCT cis rs7666738 0.800 rs2865988 chr4:99067807 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1018836 0.700 rs10504894 chr8:91516436 G/A cg16814680 chr8:91681699 NA -0.8 -7.98 -0.58 8.34e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2070433 0.539 rs2070432 chr21:47957332 G/A cg12379764 chr21:47803548 PCNT 0.52 5.17 0.42 9.2e-7 Lymphocyte counts; TGCT cis rs840163 0.512 rs7954692 chr12:57259162 A/G cg20779414 chr12:57505882 STAT6 0.44 4.85 0.4 3.64e-6 Alzheimer's disease (survival time); TGCT cis rs11864453 0.647 rs7194397 chr16:72128299 C/T cg14768367 chr16:72042858 DHODH 0.52 5.27 0.43 5.78e-7 Fibrinogen levels; TGCT cis rs9987353 0.544 rs2929470 chr8:9062490 A/G cg15556689 chr8:8085844 FLJ10661 -0.52 -5.1 -0.42 1.23e-6 Recombination measurement; TGCT cis rs9611565 0.649 rs202657 chr22:41844786 G/T cg06481639 chr22:41940642 POLR3H 0.73 6.49 0.5 1.83e-9 Vitiligo; TGCT cis rs7208859 0.573 rs216442 chr17:28931197 T/G cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7937682 0.883 rs568506 chr11:111466429 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs4689388 0.926 rs1801214 chr4:6303022 C/T cg25554036 chr4:6271136 WFS1 0.53 7.39 0.55 1.88e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs11676348 0.818 rs6436031 chr2:218979259 T/C cg00012203 chr2:219082015 ARPC2 -0.51 -4.93 -0.4 2.58e-6 Ulcerative colitis; TGCT cis rs28386778 0.830 rs2597636 chr17:61876010 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.64 0.38 8.63e-6 Prudent dietary pattern; TGCT cis rs11031096 0.678 rs12222136 chr11:4180148 T/C cg18678763 chr11:4115507 RRM1 -0.44 -5.75 -0.46 6.48e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs11650494 0.706 rs76778410 chr17:47459877 A/T cg08112188 chr17:47440006 ZNF652 1.05 4.73 0.39 6.01e-6 Prostate cancer; TGCT cis rs7017914 0.935 rs2732097 chr8:71920013 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.55 -5.1 -0.42 1.24e-6 Bone mineral density; TGCT cis rs56104184 0.775 rs56149557 chr19:49401384 C/A cg21252483 chr19:49399788 TULP2 -0.42 -5.89 -0.47 3.47e-8 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7208859 0.573 rs7214313 chr17:29138596 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs13108904 0.967 rs11730939 chr4:1285560 G/A cg03303774 chr4:1407052 NA 0.3 4.74 0.39 5.73e-6 Obesity-related traits; TGCT cis rs9467711 0.606 rs9393714 chr6:26373740 G/T cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs5769765 0.862 rs9616385 chr22:50313124 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.43 6.08 0.48 1.35e-8 Schizophrenia; TGCT cis rs1775715 0.707 rs2808094 chr10:32133756 T/C cg14930904 chr10:32216787 ARHGAP12 0.51 4.91 0.4 2.79e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs7582180 0.652 rs11675901 chr2:100951189 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.82 -0.4 4.16e-6 Intelligence (multi-trait analysis); TGCT cis rs9581857 0.556 rs9581863 chr13:28040171 A/G cg22138327 chr13:27999177 GTF3A 0.73 5.63 0.45 1.13e-7 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg08736216 chr1:53307985 ZYG11A -0.26 -5.16 -0.42 9.38e-7 Monocyte count; TGCT cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs793571 0.669 rs714696 chr15:58962987 C/G cg05156742 chr15:59063176 FAM63B 0.49 4.61 0.38 9.88e-6 Schizophrenia; TGCT cis rs56235845 0.694 rs12055081 chr5:176757191 C/T cg06060754 chr5:176797920 RGS14 0.4 6.33 0.49 3.99e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs916888 0.779 rs199528 chr17:44843136 C/T cg05721485 chr17:44071124 MAPT 0.24 4.44 0.37 1.99e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs116095464 0.558 rs62346526 chr5:220614 T/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs1218582 0.710 rs9794000 chr1:154878876 T/A cg24250549 chr1:154909240 PMVK 0.65 6.49 0.5 1.84e-9 Prostate cancer; TGCT cis rs11190604 1.000 rs11190587 chr10:102266638 C/T cg16342193 chr10:102329863 NA -0.41 -5.18 -0.42 8.61e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs35883536 0.514 rs4908062 chr1:101013211 T/C cg06223162 chr1:101003688 GPR88 0.42 8.13 0.59 3.84e-13 Monocyte count; TGCT cis rs523522 0.923 rs1048830 chr12:120882217 G/T cg12219531 chr12:120966889 COQ5 0.79 6.99 0.53 1.47e-10 High light scatter reticulocyte count; TGCT cis rs72781680 0.898 rs112985192 chr2:24102797 G/A cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs7267979 1.000 rs4813566 chr20:25386465 G/T cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7829975 0.606 rs7837026 chr8:8801692 T/C cg15556689 chr8:8085844 FLJ10661 -0.73 -6.18 -0.49 8.44e-9 Mood instability; TGCT cis rs7822232 1.000 rs7822232 chr8:145145687 A/C cg26272248 chr8:145163034 KIAA1875 -0.37 -4.68 -0.39 7.29e-6 Blood metabolite levels; TGCT cis rs9549367 0.664 rs3794419 chr13:113851874 T/C cg00898013 chr13:113819073 PROZ -0.52 -6.7 -0.52 6.5e-10 Platelet distribution width; TGCT cis rs763121 0.853 rs5757162 chr22:38993370 C/T cg06022373 chr22:39101656 GTPBP1 0.78 7.43 0.56 1.51e-11 Menopause (age at onset); TGCT cis rs10256972 0.568 rs1133043 chr7:1133305 C/G cg07092213 chr7:1199455 ZFAND2A -0.45 -4.81 -0.4 4.31e-6 Longevity;Endometriosis; TGCT cis rs2456568 0.548 rs10765647 chr11:93662459 T/C cg17595323 chr11:93583763 C11orf90 -0.42 -5.26 -0.43 6.25e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7772486 0.790 rs6924159 chr6:146267873 A/G cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs1505368 0.567 rs972491 chr2:213316573 A/G cg16329650 chr2:213403929 ERBB4 -0.84 -9.76 -0.66 4.71e-17 Symmetrical dimethylarginine levels; TGCT cis rs8177253 0.965 rs8177260 chr3:133480458 T/A cg20276088 chr3:133502917 NA -0.25 -5.1 -0.42 1.24e-6 Iron status biomarkers; TGCT cis rs10089 1.000 rs2409109 chr5:127461471 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.41 0.55 1.72e-11 Ileal carcinoids; TGCT cis rs11696501 0.688 rs6104247 chr20:44244938 C/T cg11783356 chr20:44313418 WFDC10B -0.32 -4.52 -0.38 1.41e-5 Brain structure; TGCT cis rs72781680 0.716 rs2712079 chr2:24082061 G/A cg08917208 chr2:24149416 ATAD2B 0.75 4.61 0.38 9.75e-6 Lymphocyte counts; TGCT cis rs1451375 1.000 rs921451 chr7:50623285 A/G cg18232548 chr7:50535776 DDC 0.4 6.28 0.49 5.26e-9 Malaria; TGCT cis rs9733 0.818 rs4970924 chr1:150633079 A/G cg13175981 chr1:150552382 MCL1 0.43 4.79 0.4 4.61e-6 Tonsillectomy; TGCT cis rs3849570 1.000 rs11711331 chr3:81819040 A/G cg07356753 chr3:81810745 GBE1 0.84 7.65 0.57 4.85e-12 Waist circumference;Body mass index; TGCT cis rs826838 1.000 rs11168217 chr12:38884278 T/C cg13010199 chr12:38710504 ALG10B 0.78 6.59 0.51 1.14e-9 Heart rate; TGCT cis rs986417 1.000 rs10130255 chr14:60944435 C/T cg27398547 chr14:60952738 C14orf39 1.39 10.61 0.69 4.06e-19 Gut microbiota (bacterial taxa); TGCT cis rs4713118 0.955 rs34752872 chr6:27683244 A/T cg10876282 chr6:28092338 ZSCAN16 0.5 4.62 0.38 9.35e-6 Parkinson's disease; TGCT cis rs10751667 0.857 rs7481221 chr11:966813 G/C cg06064525 chr11:970664 AP2A2 -0.36 -8.22 -0.59 2.3e-13 Alzheimer's disease (late onset); TGCT cis rs1395 0.778 rs12465084 chr2:27414203 G/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.64 8.78 0.62 1.1e-14 Blood metabolite levels; TGCT cis rs10744422 1.000 rs2292135 chr12:123334075 G/A cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs612683 0.518 rs565590 chr1:100846956 T/C cg06223162 chr1:101003688 GPR88 0.27 4.52 0.38 1.45e-5 Breast cancer; TGCT cis rs10489202 0.608 rs35059151 chr1:168079393 C/A cg24449463 chr1:168025552 DCAF6 -0.49 -5.06 -0.41 1.49e-6 Schizophrenia; TGCT cis rs6088580 0.634 rs6142164 chr20:33006597 C/T cg08999081 chr20:33150536 PIGU -0.28 -5.51 -0.44 1.96e-7 Glomerular filtration rate (creatinine); TGCT cis rs4665809 0.938 rs35844686 chr2:26304949 A/G cg22920501 chr2:26401640 FAM59B 0.74 5.78 0.46 5.68e-8 Gut microbiome composition (summer); TGCT cis rs7926906 1.000 rs1404524 chr11:90533647 T/G cg26138821 chr11:89956704 CHORDC1 -0.5 -5.33 -0.43 4.44e-7 Intelligence (multi-trait analysis); TGCT cis rs12458462 0.892 rs2007483 chr18:77476131 A/T cg11879182 chr18:77439856 CTDP1 0.71 8.04 0.59 6.07e-13 Monocyte count; TGCT cis rs11676348 0.811 rs13027120 chr2:219020914 C/T cg00012203 chr2:219082015 ARPC2 0.49 4.77 0.39 5.04e-6 Ulcerative colitis; TGCT cis rs1372520 0.808 rs1372518 chr4:90757294 A/C cg14346243 chr4:90757452 SNCA -0.64 -5.24 -0.43 6.59e-7 Neuroticism; TGCT cis rs12701220 0.817 rs1058729 chr7:1087283 C/T cg07217954 chr7:1067459 C7orf50 -0.47 -4.59 -0.38 1.08e-5 Bronchopulmonary dysplasia; TGCT cis rs17490626 0.568 rs12413523 chr10:71211664 C/G cg12610070 chr10:71211762 TSPAN15 -0.62 -7.15 -0.54 6.52e-11 Thrombosis; TGCT cis rs1008375 1.000 rs17507481 chr4:17620066 A/G cg18681998 chr4:17616180 MED28 1.07 12.0 0.73 1.7e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1552244 0.935 rs7652190 chr3:10105150 G/A cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs910316 1.000 rs11623413 chr14:75588824 C/T cg08847533 chr14:75593920 NEK9 -0.96 -11.1 -0.71 2.62e-20 Height; TGCT cis rs6933660 0.800 rs6931104 chr6:151786177 C/T cg10883421 chr6:151773342 RMND1;C6orf211 0.7 7.42 0.55 1.61e-11 Menarche (age at onset); TGCT cis rs7178572 0.524 rs7163503 chr15:77493505 C/A cg15453836 chr15:77711506 NA -0.44 -4.91 -0.4 2.86e-6 Type 2 diabetes; TGCT cis rs12220898 0.749 rs6537520 chr10:50484107 T/C cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs3749237 0.595 rs7637999 chr3:49535115 C/T cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs4821897 0.514 rs739141 chr22:39824450 A/G cg02038168 chr22:39784481 NA 0.65 5.58 0.45 1.46e-7 IgG glycosylation; TGCT cis rs9926296 0.581 rs1108064 chr16:89894150 G/C cg03388025 chr16:89894329 SPIRE2 0.35 5.18 0.42 8.89e-7 Vitiligo; TGCT trans rs4650994 1.000 rs10798616 chr1:178515642 G/C cg05059571 chr16:84539110 KIAA1609 -0.41 -7.67 -0.57 4.33e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs3749237 0.595 rs1464568 chr3:49458266 G/A cg02487422 chr3:49467188 NICN1 0.57 5.84 0.46 4.26e-8 Resting heart rate; TGCT cis rs4889855 0.545 rs61171555 chr17:78465975 T/G cg16591659 chr17:78472290 NA -0.36 -5.61 -0.45 1.26e-7 Fractional excretion of uric acid; TGCT cis rs7937682 0.883 rs11213941 chr11:111434094 T/C cg09085632 chr11:111637200 PPP2R1B 0.99 9.52 0.65 1.82e-16 Primary sclerosing cholangitis; TGCT cis rs9326248 0.954 rs8521 chr11:117067699 C/T cg16524733 chr11:117070046 TAGLN 0.34 4.91 0.4 2.77e-6 Blood protein levels; TGCT cis rs10782582 0.609 rs11161848 chr1:76367722 A/G cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.54 4.6 0.38 1.02e-5 Daytime sleep phenotypes; TGCT cis rs6752107 0.936 rs1045100 chr2:234203597 T/C cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 4.71 0.39 6.47e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs6540559 0.546 rs59435160 chr1:210030730 C/A cg04352962 chr1:209979756 IRF6 0.75 5.29 0.43 5.32e-7 Cleft lip with or without cleft palate; TGCT cis rs10751667 0.643 rs7479473 chr11:929111 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.54e-13 Alzheimer's disease (late onset); TGCT cis rs9549367 0.826 rs2287249 chr13:113889355 A/G cg00898013 chr13:113819073 PROZ -0.4 -4.92 -0.4 2.7e-6 Platelet distribution width; TGCT cis rs7312774 0.618 rs4964510 chr12:107357251 A/G cg16260113 chr12:107380972 MTERFD3 1.02 5.27 0.43 5.92e-7 Severe influenza A (H1N1) infection; TGCT cis rs2832191 0.632 rs1984011 chr21:30337831 T/A cg24692254 chr21:30365293 RNF160 -1.0 -11.42 -0.72 4.34e-21 Dental caries; TGCT cis rs9296661 0.765 rs927859 chr6:51668970 T/G cg00593404 chr6:52377740 TRAM2 -0.28 -4.56 -0.38 1.19e-5 Weight loss (gastric bypass surgery); TGCT cis rs4478858 0.735 rs6676354 chr1:31800746 A/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs2299587 0.698 rs2283113 chr8:17880243 C/A cg08627089 chr8:17753878 FGL1 -0.28 -4.73 -0.39 5.97e-6 Economic and political preferences; TGCT cis rs13108904 0.967 rs13109112 chr4:1290481 C/A cg13395646 chr4:1353034 KIAA1530 -0.4 -5.0 -0.41 1.93e-6 Obesity-related traits; TGCT cis rs2840044 1.000 rs9900378 chr17:33911302 C/T cg05299278 chr17:33885742 SLFN14 -0.23 -5.05 -0.41 1.53e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs11122272 0.735 rs10489611 chr1:231517854 A/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.13 -0.54 7.33e-11 Hemoglobin concentration; TGCT cis rs9929218 0.529 rs11640736 chr16:68738324 G/T cg01251360 chr16:68772225 CDH1 -0.25 -4.49 -0.37 1.64e-5 Colorectal cancer; TGCT cis rs1008375 1.000 rs10939738 chr4:17604295 G/C cg18681998 chr4:17616180 MED28 0.98 10.43 0.68 1.17e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs950776 0.518 rs62008194 chr15:78813805 G/T cg06917634 chr15:78832804 PSMA4 0.96 9.71 0.66 6.43e-17 Sudden cardiac arrest; TGCT cis rs4819052 1.000 rs2297285 chr21:46705621 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 -0.89 -6.62 -0.51 9.85e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs9379945 1 rs9379945 chr6:26907831 T/C cg15633603 chr2:190399258 NA 0.4 6.96 0.53 1.74e-10 Intelligence (multi-trait analysis); TGCT cis rs13191362 0.872 rs35443919 chr6:163055804 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.06 8.12 0.59 3.96e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3806843 0.606 rs251377 chr5:140255792 C/A cg09824255 chr5:140014002 CD14 -0.26 -4.54 -0.38 1.3e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs950169 0.509 rs71395455 chr15:85153804 A/G cg11189052 chr15:85197271 WDR73 0.78 6.71 0.52 6.11e-10 Schizophrenia; TGCT cis rs6714710 0.603 rs1470483 chr2:98393894 C/T cg26665480 chr2:98280029 ACTR1B 0.68 6.49 0.5 1.85e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs7811142 1.000 rs73405353 chr7:100091215 G/A cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.05 -9.36 -0.64 4.35e-16 Platelet count; TGCT trans rs561341 0.528 rs11650908 chr17:30195425 T/C cg20587970 chr11:113659929 NA 0.58 7.41 0.55 1.68e-11 Hip circumference adjusted for BMI; TGCT cis rs1568889 1.000 rs11602768 chr11:28351786 G/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.19 0.59 2.67e-13 Bipolar disorder; TGCT cis rs5750830 0.594 rs6001568 chr22:39775786 G/A cg11247378 chr22:39784982 NA -0.65 -8.71 -0.62 1.59e-14 Intelligence (multi-trait analysis); TGCT cis rs155076 1.000 rs261407 chr13:21855213 C/A cg14456004 chr13:21872349 NA -1.23 -10.21 -0.68 3.9e-18 White matter hyperintensity burden; TGCT cis rs57221529 0.713 rs72703072 chr5:590626 A/G cg09021430 chr5:549028 NA -0.38 -5.06 -0.41 1.45e-6 Lung disease severity in cystic fibrosis; TGCT cis rs7552404 0.731 rs5745491 chr1:76350159 T/G cg03433033 chr1:76189801 ACADM -0.74 -7.5 -0.56 1.09e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2797160 1.000 rs1777222 chr6:126021030 C/T cg05901451 chr6:126070800 HEY2 0.75 6.66 0.51 8e-10 Endometrial cancer; TGCT cis rs9549367 0.713 rs556990 chr13:113845059 T/C cg18105134 chr13:113819100 PROZ 0.46 8.58 0.61 3.25e-14 Platelet distribution width; TGCT cis rs9330264 0.508 rs7364869 chr1:155087188 A/G cg23973274 chr1:155060172 NA -0.26 -4.69 -0.39 7.1e-6 1,5-anhydroglucitol levels; TGCT cis rs7267979 1.000 rs6107045 chr20:25441936 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1878931 0.615 rs6501171 chr16:3402610 T/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.91 10.37 0.68 1.63e-18 Body mass index (adult); TGCT cis rs9457247 1.000 rs364451 chr6:167384756 G/A cg25258033 chr6:167368657 RNASET2 0.2 4.82 0.4 4.03e-6 Crohn's disease; TGCT cis rs2201728 0.967 rs13104485 chr4:100140823 T/A cg07219303 chr4:100140905 ADH6 -0.35 -5.22 -0.42 7.29e-7 Cardiac Troponin-T levels; TGCT cis rs4523957 0.690 rs28505924 chr17:2088838 G/C cg16513277 chr17:2031491 SMG6 -0.2 -4.52 -0.38 1.42e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs6762477 0.715 rs12631337 chr3:50198537 A/G cg21659725 chr3:3221576 CRBN -0.71 -8.05 -0.59 5.86e-13 Menarche (age at onset); TGCT cis rs4988958 0.565 rs6732138 chr2:103009662 G/A cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma (childhood onset); TGCT cis rs758129 0.578 rs1006660 chr15:89883520 T/C cg01877814 chr15:89879097 POLG 0.31 4.46 0.37 1.8e-5 Schizophrenia; TGCT cis rs9653442 0.527 rs4851258 chr2:100780830 T/C cg22139774 chr2:100720529 AFF3 -0.36 -5.69 -0.46 8.67e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs7212196 chr17:61834981 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs1757171 0.542 rs3818985 chr6:37484214 G/T cg08126542 chr6:37504118 NA -0.42 -6.2 -0.49 7.66e-9 Cognitive performance; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg15242686 chr22:24348715 GSTTP1 0.49 7.39 0.55 1.88e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3806843 0.576 rs246020 chr5:140334771 G/A cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs1635 0.655 rs16893917 chr6:28269407 G/A cg15743358 chr6:28303923 ZNF323 -1.34 -5.96 -0.47 2.44e-8 Schizophrenia; TGCT cis rs265548 0.608 rs265545 chr19:17903465 C/T cg16744531 chr19:17905626 B3GNT3 0.4 4.92 0.4 2.65e-6 Tumor biomarkers; TGCT cis rs7727544 0.716 rs3844312 chr5:131582356 C/T cg21474247 chr5:131268130 NA 0.31 4.63 0.38 8.95e-6 Blood metabolite levels; TGCT cis rs6049375 1.000 rs6049375 chr20:24058407 A/G cg14741141 chr20:24973699 C20orf3 -0.65 -4.6 -0.38 1.03e-5 Erectile dysfunction and prostate cancer treatment; TGCT cis rs7584330 0.910 rs6713555 chr2:238398182 A/G cg16989719 chr2:238392110 NA 0.3 4.65 0.39 8.28e-6 Prostate cancer; TGCT cis rs1534166 0.647 rs9853615 chr3:133519981 C/T cg08048268 chr3:133502702 NA -0.47 -5.82 -0.46 4.78e-8 Alcohol consumption (transferrin glycosylation); TGCT cis rs7666738 0.830 rs11935078 chr4:99010476 T/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs35306767 0.715 rs11253550 chr10:1028288 C/G cg18964960 chr10:1102726 WDR37 0.74 5.31 0.43 4.97e-7 Eosinophil percentage of granulocytes; TGCT cis rs28785552 1.000 rs28785552 chr19:53234161 G/A cg04754360 chr19:53238445 ZNF611 -0.59 -4.55 -0.38 1.26e-5 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs2243480 1.000 rs7794661 chr7:65389730 T/C cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs6964587 0.869 rs7810391 chr7:91520227 G/A cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs4886920 0.563 rs4886915 chr15:78075023 A/G cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.36e-6 Neuroticism; TGCT cis rs2742417 0.624 rs2673029 chr3:45758867 A/G cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9611565 0.659 rs9611609 chr22:41945357 C/A cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg12310025 chr6:25882481 NA -0.67 -5.84 -0.46 4.3e-8 Intelligence (multi-trait analysis); TGCT cis rs1915146 0.546 rs1715862 chr10:126856255 C/T cg23000734 chr10:126850823 CTBP2 -0.46 -5.01 -0.41 1.8e-6 Menarche (age at onset); TGCT cis rs62055045 0.722 rs62055056 chr16:71418999 G/A cg09204302 chr16:70713462 MTSS1L -0.31 -4.93 -0.4 2.62e-6 Schizophrenia; TGCT cis rs2486012 1.000 rs61770286 chr1:44356609 A/G cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.855 rs4809459 chr20:61661345 C/T cg18188782 chr20:61659543 NA 0.44 5.38 0.43 3.6e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs763121 0.819 rs3747173 chr22:39069045 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs3733585 0.673 rs7672947 chr4:9961368 G/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6138458 1.000 rs6114980 chr20:24974288 A/G cg26195577 chr20:24973756 C20orf3 1.22 12.1 0.74 9.98e-23 Blood protein levels; TGCT cis rs4713118 0.527 rs35949862 chr6:28115367 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Parkinson's disease; TGCT cis rs6426558 0.537 rs10495253 chr1:227471820 A/T cg10327440 chr1:227177885 CDC42BPA 0.57 6.65 0.51 8.55e-10 Neutrophil percentage of white cells; TGCT cis rs7809950 0.678 rs13230144 chr7:106909172 T/C cg23024343 chr7:107201750 COG5 -0.43 -5.81 -0.46 4.86e-8 Coronary artery disease; TGCT cis rs2739330 0.828 rs4822454 chr22:24255208 G/A cg25703541 chr22:24373054 LOC391322 -0.81 -8.44 -0.6 6.94e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13108904 0.870 rs4974542 chr4:1250908 A/G cg03303774 chr4:1407052 NA 0.3 4.78 0.39 4.8e-6 Obesity-related traits; TGCT cis rs950169 0.922 rs62021167 chr15:85118051 T/A cg17173187 chr15:85201210 NMB 0.47 4.95 0.41 2.39e-6 Schizophrenia; TGCT cis rs11971779 0.648 rs6967836 chr7:139079944 C/G cg07862535 chr7:139043722 LUC7L2 0.57 4.52 0.38 1.42e-5 Diisocyanate-induced asthma; TGCT cis rs2549003 1.000 rs9282763 chr5:131822133 T/C cg21138405 chr5:131827807 IRF1 0.19 4.79 0.39 4.76e-6 Asthma (sex interaction); TGCT cis rs4819052 0.851 rs1999333 chr21:46670401 C/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.72 0.39 6.26e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7599312 0.534 rs6751692 chr2:213408120 C/T cg20637307 chr2:213403960 ERBB4 0.92 11.46 0.72 3.54e-21 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs3087591 0.708 rs9894648 chr17:29653293 T/C cg24425628 chr17:29625626 OMG;NF1 0.35 5.01 0.41 1.82e-6 Hip circumference; TGCT cis rs28785552 0.897 rs34244888 chr19:53242228 T/A cg04754360 chr19:53238445 ZNF611 -0.68 -5.66 -0.45 9.86e-8 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs644799 0.965 rs565771 chr11:95644179 T/A cg25622487 chr11:95524042 FAM76B;CEP57 0.75 8.08 0.59 4.98e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs554111 0.656 rs6685914 chr1:21362378 G/A cg01072550 chr1:21505969 NA 0.35 5.27 0.43 5.91e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs9926296 0.605 rs8047486 chr16:89854025 A/T cg26513180 chr16:89883248 FANCA 1.07 14.96 0.8 1.48e-29 Vitiligo; TGCT cis rs4499344 0.881 rs6510263 chr19:33067367 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.68 -5.95 -0.47 2.59e-8 Mean platelet volume; TGCT cis rs10949834 0.715 rs710968 chr7:73497728 A/G cg07137043 chr7:73588983 EIF4H 0.63 4.61 0.38 1.01e-5 Verbal memory performance (residualized delayed recall change); TGCT cis rs7191439 0.728 rs8043637 chr16:88781125 T/C cg27087555 chr16:88793112 FAM38A -0.47 -5.36 -0.43 3.91e-7 Plateletcrit; TGCT trans rs208520 0.874 rs208515 chr6:66945749 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.93 -0.67 1.84e-17 Exhaled nitric oxide output; TGCT cis rs4642101 0.662 rs57411588 chr3:12820384 C/G cg05775895 chr3:12838266 CAND2 0.92 11.11 0.71 2.53e-20 QRS complex (12-leadsum); TGCT cis rs8072100 0.790 rs11079783 chr17:45686016 C/T cg10024583 chr17:45772800 TBKBP1 -0.43 -4.47 -0.37 1.76e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs1799949 1.000 rs34572725 chr17:41428666 G/A cg23758822 chr17:41437982 NA 0.7 6.6 0.51 1.1e-9 Menopause (age at onset); TGCT cis rs3820068 0.581 rs1122386 chr1:15946877 C/T cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.26e-13 Systolic blood pressure; TGCT cis rs3845702 0.736 rs72960701 chr2:180851202 A/T cg01881094 chr2:180872142 CWC22 1.03 6.55 0.51 1.35e-9 Schizophrenia; TGCT cis rs1552244 1.000 rs12374115 chr3:10134766 A/G cg02579736 chr3:10068473 FANCD2;CIDECP -0.93 -5.95 -0.47 2.57e-8 Alzheimer's disease; TGCT cis rs921968 0.541 rs3770214 chr2:219508988 C/T cg02176678 chr2:219576539 TTLL4 -0.49 -6.82 -0.52 3.52e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs950169 0.922 rs12912934 chr15:85114447 C/T cg12863693 chr15:85201151 NMB 0.39 4.44 0.37 1.99e-5 Schizophrenia; TGCT cis rs7937682 0.889 rs2850247 chr11:111637202 C/A cg19812747 chr11:111475976 SIK2 0.39 4.61 0.38 9.74e-6 Primary sclerosing cholangitis; TGCT cis rs5769765 0.954 rs5770739 chr22:50268014 C/G cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs2239547 0.522 rs6773040 chr3:52935428 C/A cg10802521 chr3:52805072 NEK4 0.63 5.88 0.47 3.48e-8 Schizophrenia; TGCT cis rs9325144 0.505 rs826893 chr12:39100536 A/G cg26384229 chr12:38710491 ALG10B -0.82 -7.79 -0.57 2.28e-12 Morning vs. evening chronotype; TGCT cis rs6061231 0.583 rs2427313 chr20:60970675 G/A cg22633769 chr20:60982531 CABLES2 0.57 4.54 0.38 1.29e-5 Colorectal cancer; TGCT cis rs2204008 0.775 rs11514370 chr12:38305566 G/A cg26384229 chr12:38710491 ALG10B 0.78 6.9 0.53 2.33e-10 Bladder cancer; TGCT cis rs1185460 0.967 rs1184902 chr11:118945337 A/G cg01677386 chr11:118938358 VPS11 -0.53 -4.51 -0.38 1.47e-5 Coronary artery disease; TGCT cis rs62244186 0.541 rs3804583 chr3:44884647 G/T cg10108389 chr3:44770937 ZNF501 -0.48 -4.75 -0.39 5.45e-6 Depressive symptoms; TGCT cis rs10882165 0.779 rs11596090 chr10:94909481 C/T cg15980076 chr10:94822747 CYP26C1 0.45 4.82 0.4 4.2e-6 Refractive error; TGCT cis rs9952991 0.941 rs2542150 chr18:12779763 G/C cg23544223 chr18:12777786 NA 0.64 6.12 0.48 1.15e-8 Inflammatory skin disease; TGCT cis rs782590 0.620 rs4322879 chr2:55797033 G/T cg18811423 chr2:55921094 PNPT1 -0.63 -6.07 -0.48 1.47e-8 Metabolic syndrome; TGCT cis rs4665809 0.590 rs7260 chr2:26413917 C/T cg22920501 chr2:26401640 FAM59B -0.8 -6.43 -0.5 2.55e-9 Gut microbiome composition (summer); TGCT cis rs2594989 0.779 rs56053623 chr3:11592153 T/C cg00170343 chr3:11313890 ATG7 -0.7 -5.24 -0.43 6.66e-7 Circulating chemerin levels; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg06873352 chr17:61820015 STRADA 0.56 6.22 0.49 7.03e-9 Prudent dietary pattern; TGCT trans rs1814175 0.817 rs1390676 chr11:50056778 C/T cg15704280 chr7:45808275 SEPT13 -0.72 -8.47 -0.61 6.02e-14 Height; TGCT cis rs7772486 0.790 rs9376970 chr6:146241472 A/C cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.42e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.929 rs557715 chr1:53321593 C/G cg25767906 chr1:53392781 SCP2 -0.52 -6.19 -0.49 8.06e-9 Monocyte count; TGCT cis rs13118159 0.836 rs12647145 chr4:1338618 C/A cg22683308 chr4:1340831 KIAA1530 -0.65 -6.11 -0.48 1.19e-8 Longevity; TGCT cis rs2739330 0.752 rs2330634 chr22:24250795 C/G cg02953382 chr22:24373134 LOC391322 -0.72 -7.08 -0.54 9.43e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs263156 1.000 rs263122 chr6:142894794 T/C cg18419694 chr6:143832440 FUCA2 -0.4 -4.66 -0.39 8.05e-6 Ear morphology;Lobe size;Lobe attachment; TGCT cis rs9911578 0.967 rs11079368 chr17:57086473 C/T cg05425664 chr17:57184151 TRIM37 0.68 6.9 0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs739496 0.843 rs595529 chr12:112000648 A/T cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs2594989 0.887 rs7632902 chr3:11476884 T/C cg00170343 chr3:11313890 ATG7 0.79 5.8 0.46 5.18e-8 Circulating chemerin levels; TGCT cis rs9394438 0.628 rs4714079 chr6:37544439 C/T cg00985040 chr6:37553208 NA -0.25 -5.0 -0.41 1.94e-6 IgG glycosylation; TGCT cis rs853679 0.713 rs200991 chr6:27815494 A/C cg01031101 chr6:28227091 NKAPL 0.38 4.49 0.37 1.62e-5 Depression; TGCT cis rs2762353 0.574 rs34067542 chr6:25728210 T/A cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC 0.71 7.56 0.56 7.98e-12 Blood metabolite levels; TGCT cis rs981844 0.689 rs7666762 chr4:154684197 C/T cg14289246 chr4:154710475 SFRP2 -0.89 -8.17 -0.59 3.09e-13 Response to statins (LDL cholesterol change); TGCT cis rs79349575 0.783 rs12602746 chr17:47031741 A/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs28386778 0.897 rs2665831 chr17:61912392 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.52 4.52 0.38 1.44e-5 Prudent dietary pattern; TGCT cis rs10782582 0.609 rs111914775 chr1:76319036 C/T cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs6570726 0.791 rs414600 chr6:145879606 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.93 0.67 1.82e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs13202913 0.837 rs9397052 chr6:151779228 C/T cg03627880 chr6:151815985 C6orf97 -0.76 -5.85 -0.47 4.05e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs17345786 0.954 rs17508319 chr3:101318903 G/A cg11279151 chr3:101281821 RG9MTD1 -0.44 -9.59 -0.65 1.25e-16 Colonoscopy-negative controls vs population controls; TGCT cis rs9653442 0.545 rs11681227 chr2:100754997 A/G cg07810366 chr2:100720526 AFF3 -0.36 -5.09 -0.42 1.27e-6 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs8062405 0.789 rs28676837 chr16:28627063 C/T cg09754948 chr16:28834200 ATXN2L -0.58 -4.67 -0.39 7.76e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2032447 0.670 rs198848 chr6:26106325 A/G cg12310025 chr6:25882481 NA -0.51 -4.68 -0.39 7.46e-6 Intelligence (multi-trait analysis); TGCT cis rs62244186 0.659 rs1806579 chr3:44509281 T/C cg15687855 chr3:44754131 ZNF502 -0.43 -5.24 -0.43 6.74e-7 Depressive symptoms; TGCT cis rs2050392 0.767 rs1536833 chr10:30699265 C/T cg18806716 chr10:30721971 MAP3K8 0.69 9.16 0.64 1.37e-15 Inflammatory bowel disease; TGCT cis rs9733 0.596 rs2065900 chr1:150652202 A/G cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.59e-6 Tonsillectomy; TGCT cis rs362272 0.505 rs3129310 chr4:3301388 T/G cg06533319 chr4:3265114 C4orf44 -0.26 -5.12 -0.42 1.13e-6 Serum sulfate level; TGCT cis rs4557202 0.509 rs12690576 chr3:160647912 G/A cg03342759 chr3:160939853 NMD3 -0.47 -4.57 -0.38 1.17e-5 Menarche (age at onset); TGCT cis rs35146811 1.000 rs35146811 chr7:99720994 A/C cg13334819 chr7:99746414 C7orf59 -0.82 -7.34 -0.55 2.49e-11 Coronary artery disease; TGCT cis rs4566357 1.000 rs2177597 chr2:227922546 C/T cg11843606 chr2:227700838 RHBDD1 -0.58 -5.31 -0.43 4.92e-7 Coronary artery disease; TGCT cis rs6089584 0.853 rs1746280 chr20:60577821 C/G cg16423285 chr20:60520624 NA -0.6 -6.69 -0.51 6.91e-10 Body mass index; TGCT trans rs3790455 0.610 rs3790461 chr1:156469364 A/G cg16443977 chr5:115884994 SEMA6A -0.38 -7.12 -0.54 7.51e-11 Migraine; TGCT cis rs6684514 1.000 rs12023704 chr1:156294149 C/A cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7267979 0.789 rs4815429 chr20:25521611 T/C cg03522245 chr20:25566470 NINL -0.56 -5.79 -0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs651907 0.935 rs2926538 chr3:101587585 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.46 4.76 0.39 5.25e-6 Colorectal cancer; TGCT cis rs5850 0.602 rs1005786 chr7:23145837 G/C cg05602783 chr7:23145260 KLHL7 -0.65 -5.8 -0.46 5.23e-8 Blood protein levels; TGCT cis rs9534288 0.957 rs2404731 chr13:46618384 T/C cg15192986 chr13:46630673 CPB2 -0.49 -6.18 -0.49 8.64e-9 Blood protein levels; TGCT cis rs7772486 0.790 rs1832362 chr6:146179955 C/T cg05347473 chr6:146136440 FBXO30 0.51 4.77 0.39 5.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs55794721 0.509 rs873308 chr1:25758655 A/G cg10117171 chr1:25599238 RHD 0.36 6.03 0.48 1.71e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs514406 0.792 rs481440 chr1:53344976 C/T cg27535305 chr1:53392650 SCP2 -0.28 -5.89 -0.47 3.35e-8 Monocyte count; TGCT cis rs2073300 1.000 rs12625160 chr20:23442008 T/C cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs10479542 0.892 rs7736163 chr5:178980316 G/C cg14820908 chr5:178986412 RUFY1 0.45 4.56 0.38 1.23e-5 Lung cancer; TGCT cis rs6570726 0.557 rs403956 chr6:145829956 T/C cg13319975 chr6:146136371 FBXO30 -0.65 -5.77 -0.46 5.93e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs9911578 0.835 rs58647683 chr17:56483194 T/C cg05425664 chr17:57184151 TRIM37 0.61 5.76 0.46 6.33e-8 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.501 rs13008171 chr2:99743419 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs6570726 0.846 rs9376954 chr6:145943737 T/A cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs116095464 0.558 rs2288458 chr5:231260 C/T cg22857025 chr5:266934 NA -0.33 -6.6 -0.51 1.1e-9 Breast cancer; TGCT cis rs5751150 1 rs5751150 chr22:42153292 T/G cg17554472 chr22:41940697 POLR3H 0.46 4.69 0.39 7.09e-6 Cannabis dependence symptom count; TGCT cis rs10510102 0.872 rs12257207 chr10:123701252 C/T cg23691251 chr10:123688108 ATE1 -0.58 -4.58 -0.38 1.11e-5 Breast cancer; TGCT cis rs7647973 0.626 rs9829155 chr3:49817450 T/C cg05785598 chr3:49045655 WDR6 -0.42 -5.24 -0.43 6.67e-7 Menarche (age at onset); TGCT cis rs4319547 0.737 rs7964138 chr12:122950375 A/G cg23029597 chr12:123009494 RSRC2 -0.28 -4.67 -0.39 7.8e-6 Body mass index; TGCT cis rs9796 0.870 rs3214068 chr15:41313064 C/G cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.41 -0.44 3.06e-7 Menopause (age at onset); TGCT cis rs9467773 0.620 rs2494716 chr6:26662736 T/C cg15659132 chr6:26577336 NA 0.87 10.72 0.69 2.19e-19 Intelligence (multi-trait analysis); TGCT cis rs7225537 0.509 rs11870035 chr17:17033397 C/T cg26176665 chr17:16994978 MPRIP 0.25 5.9 0.47 3.22e-8 Mean platelet volume; TGCT cis rs7586879 0.658 rs7563204 chr2:25125075 T/G cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs7772486 0.720 rs6570713 chr6:146075085 G/A cg05347473 chr6:146136440 FBXO30 -0.54 -4.95 -0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 1.000 rs6972167 chr7:100080013 G/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.98 8.15 0.59 3.28e-13 Platelet count; TGCT cis rs10254284 0.959 rs1109483 chr7:28145031 C/T cg23620719 chr7:28220237 JAZF1 0.54 4.94 0.41 2.52e-6 Lymphocyte percentage of white cells;Systemic lupus erythematosus; TGCT cis rs908922 0.676 rs549044 chr1:152514332 C/T cg20991723 chr1:152506922 NA 0.42 5.87 0.47 3.77e-8 Hair morphology; TGCT cis rs875971 0.660 rs62465434 chr7:66005152 A/C cg18876405 chr7:65276391 NA 0.36 5.41 0.44 3.12e-7 Aortic root size; TGCT cis rs669446 0.561 rs516790 chr1:44081712 G/T cg12908607 chr1:44402522 ARTN 0.55 5.9 0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs523522 0.847 rs11065132 chr12:120908459 C/T cg12219531 chr12:120966889 COQ5 0.83 7.33 0.55 2.6e-11 High light scatter reticulocyte count; TGCT cis rs13242816 1.000 rs56250718 chr7:116103303 A/G cg16553024 chr7:116138462 CAV2 -0.43 -4.8 -0.4 4.41e-6 P wave duration; TGCT cis rs11098499 0.909 rs73842633 chr4:120375464 G/A cg09307838 chr4:120376055 NA 0.67 6.29 0.49 4.88e-9 Corneal astigmatism; TGCT cis rs7513165 0.542 rs4951317 chr1:204161507 C/T cg12731349 chr1:204159619 KISS1 0.45 5.36 0.43 3.91e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs2839186 0.807 rs2032226 chr21:47680352 G/A cg05896524 chr21:47604654 C21orf56 0.42 4.47 0.37 1.74e-5 Testicular germ cell tumor; TGCT cis rs1894292 0.527 rs6852149 chr4:74369540 C/G cg05868023 chr4:75230803 EREG -0.52 -4.64 -0.38 8.72e-6 Prostate cancer; TGCT cis rs6964587 1.000 rs12704635 chr7:91737324 T/G cg17063962 chr7:91808500 NA 0.88 9.59 0.65 1.22e-16 Breast cancer; TGCT cis rs4319547 0.695 rs4758666 chr12:122902840 C/T cg08088222 chr12:122070432 ORAI1 0.25 4.5 0.37 1.54e-5 Body mass index; TGCT cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg04317338 chr11:64019027 PLCB3 0.5 4.62 0.38 9.36e-6 Platelet count; TGCT cis rs3806843 0.576 rs246066 chr5:140323147 T/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.43 -5.48 -0.44 2.27e-7 Depressive symptoms (multi-trait analysis); TGCT trans rs2688608 1.000 rs2688608 chr10:75658349 G/T cg13918328 chr10:52500089 ASAH2B 0.65 6.7 0.52 6.47e-10 Inflammatory bowel disease; TGCT trans rs17685 0.672 rs1639618 chr7:75701987 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6988636 1.000 rs13261021 chr8:124190239 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs829880 0.570 rs4488248 chr12:98853688 G/C cg25150519 chr12:98850993 NA 0.64 5.76 0.46 6.2e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs240764 0.658 rs9322213 chr6:101248480 T/C cg21058520 chr6:100914733 NA 0.35 4.53 0.38 1.36e-5 Neuroticism; TGCT cis rs1153858 1.000 rs4774577 chr15:45644685 A/C cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs10464366 0.560 rs11763728 chr7:39145862 C/T cg18850127 chr7:39170497 POU6F2 0.26 5.95 0.47 2.57e-8 IgG glycosylation; TGCT cis rs7119 0.635 rs59745219 chr15:77884130 A/G cg27398640 chr15:77910606 LINGO1 0.33 6.88 0.53 2.68e-10 Type 2 diabetes; TGCT cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs4862750 0.872 rs13110072 chr4:187878524 A/G cg03452623 chr4:187889614 NA -0.37 -5.53 -0.44 1.84e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2013441 1.000 rs2526490 chr17:20097526 A/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs4820539 0.966 rs2157709 chr22:23457420 T/C cg21100191 chr22:23484243 RTDR1 0.95 11.4 0.72 4.85e-21 Bone mineral density; TGCT cis rs9393777 0.720 rs35769282 chr6:26999908 G/C cg16898833 chr6:26189333 HIST1H4D 0.97 5.95 0.47 2.6e-8 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs894406 chr17:61901657 A/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs514406 0.584 rs7548832 chr1:53193576 A/T cg08859206 chr1:53392774 SCP2 -0.36 -5.07 -0.41 1.38e-6 Monocyte count; TGCT cis rs2836950 0.545 rs11701805 chr21:40618683 T/C cg17971929 chr21:40555470 PSMG1 -0.54 -4.87 -0.4 3.32e-6 Menarche (age at onset); TGCT cis rs904251 0.861 rs1757173 chr6:37486952 A/C cg08126542 chr6:37504118 NA -0.44 -5.92 -0.47 2.96e-8 Cognitive performance; TGCT cis rs17197710 0.673 rs12575296 chr11:47320985 A/G cg13308137 chr11:47528955 CUGBP1 -0.41 -5.82 -0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6582630 0.502 rs11522899 chr12:38270637 T/C cg13010199 chr12:38710504 ALG10B 0.64 4.97 0.41 2.15e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4906332 1.000 rs12885762 chr14:103882200 C/A cg26031613 chr14:104095156 KLC1 -0.51 -4.63 -0.38 9.17e-6 Coronary artery disease; TGCT cis rs950169 1.000 rs35648189 chr15:84740748 T/C cg17173187 chr15:85201210 NMB 0.47 5.23 0.42 7.11e-7 Schizophrenia; TGCT cis rs11779988 0.545 rs448882 chr8:17794039 C/T cg01800426 chr8:17659068 MTUS1 -0.68 -5.41 -0.44 3.14e-7 Breast cancer; TGCT cis rs6089584 0.508 rs6061988 chr20:60626300 C/T cg06108461 chr20:60628389 TAF4 -0.41 -4.91 -0.4 2.86e-6 Body mass index; TGCT cis rs7666738 0.830 rs13149779 chr4:99010145 G/T cg18180107 chr4:99064573 C4orf37 0.55 5.01 0.41 1.81e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2276314 1.000 rs4573997 chr18:33552568 C/T cg19628046 chr18:33552617 C18orf21 0.53 4.5 0.37 1.53e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs7666738 0.830 rs10470894 chr4:99039107 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1887596 0.705 rs541816 chr13:27204062 T/G cg01312412 chr13:27282625 NA 0.28 4.98 0.41 2.05e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs3806843 0.569 rs753279 chr5:140023818 A/G cg19875535 chr5:140030758 IK -0.28 -4.56 -0.38 1.2e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs523522 0.962 rs3742052 chr12:120966921 A/G cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs17761864 1.000 rs1466389 chr17:2096384 C/T cg02171503 chr17:1588363 PRPF8 -0.48 -4.65 -0.39 8.34e-6 Esophageal cancer (squamous cell); TGCT cis rs9291683 0.588 rs13113730 chr4:10017628 C/T cg00071950 chr4:10020882 SLC2A9 0.75 10.33 0.68 2.04e-18 Bone mineral density; TGCT cis rs6933660 0.745 rs9397405 chr6:151736084 G/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.87 -9.34 -0.64 4.97e-16 Menarche (age at onset); TGCT cis rs344364 0.511 rs62040571 chr16:1948514 C/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs3091242 0.933 rs926438 chr1:25753638 C/T cg00786635 chr1:25594202 NA 0.55 5.75 0.46 6.46e-8 Erythrocyte sedimentation rate; TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg11905131 chr22:24372483 LOC391322 -0.95 -11.19 -0.71 1.64e-20 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2777491 1.000 rs316613 chr15:41747598 G/A cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.07 -0.71 3.15e-20 Ulcerative colitis; TGCT cis rs7666738 0.800 rs10028921 chr4:98962630 G/T cg18180107 chr4:99064573 C4orf37 0.57 5.11 0.42 1.16e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT trans rs6951245 0.554 rs58210047 chr7:1149381 G/A cg13565492 chr6:43139072 SRF -0.82 -7.87 -0.58 1.51e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9399137 0.507 rs4594969 chr6:135285586 A/T cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs7513165 0.660 rs12040249 chr1:204158228 C/T cg12731349 chr1:204159619 KISS1 0.43 4.92 0.4 2.71e-6 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs7552404 0.731 rs11161857 chr1:76370228 G/C cg03433033 chr1:76189801 ACADM 0.75 7.09 0.54 8.86e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4455778 0.659 rs13312049 chr7:49023488 C/T cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs9325144 0.555 rs7968322 chr12:38792348 T/C cg26384229 chr12:38710491 ALG10B -0.61 -5.72 -0.46 7.51e-8 Morning vs. evening chronotype; TGCT cis rs7727544 0.735 rs272875 chr5:131674888 T/C cg14196790 chr5:131705035 SLC22A5 0.32 4.48 0.37 1.69e-5 Blood metabolite levels; TGCT cis rs1005277 0.563 rs2505216 chr10:38482830 T/C cg25427524 chr10:38739819 LOC399744 -0.41 -8.54 -0.61 4.04e-14 Extrinsic epigenetic age acceleration; TGCT cis rs7677751 0.767 rs7676985 chr4:55064573 G/A cg17187183 chr4:55093834 PDGFRA 0.49 6.49 0.5 1.84e-9 Corneal astigmatism; TGCT cis rs36051895 0.659 rs1576271 chr9:5039652 A/C cg02405213 chr9:5042618 JAK2 -0.78 -10.18 -0.67 4.7e-18 Pediatric autoimmune diseases; TGCT cis rs2404602 0.669 rs1875885 chr15:76638081 G/A cg22467129 chr15:76604101 ETFA -0.57 -6.86 -0.52 2.88e-10 Blood metabolite levels; TGCT cis rs7786808 0.782 rs7787923 chr7:158227312 A/G cg01191920 chr7:158217561 PTPRN2 -0.39 -5.63 -0.45 1.13e-7 Obesity-related traits; TGCT trans rs10953454 1.000 rs10227564 chr7:104491237 C/A cg04208666 chr6:19734707 NA -0.57 -6.84 -0.52 3.27e-10 Obesity; TGCT cis rs2439831 0.867 rs2255051 chr15:43846161 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.79 0.46 5.33e-8 Lung cancer in ever smokers; TGCT cis rs831571 0.519 rs13059603 chr3:63827381 C/T cg16258503 chr3:63850278 ATXN7;THOC7 0.65 5.42 0.44 2.98e-7 Type 2 diabetes; TGCT cis rs80282103 0.867 rs74117668 chr10:1076620 C/T cg15531433 chr10:1639090 ADARB2 0.41 4.5 0.37 1.52e-5 Glomerular filtration rate (creatinine); TGCT cis rs854765 0.547 rs6502633 chr17:17941037 G/C cg04398451 chr17:18023971 MYO15A -0.33 -5.27 -0.43 5.77e-7 Total body bone mineral density; TGCT cis rs11214775 0.500 rs7943062 chr11:113817286 C/T cg20857767 chr11:113147175 NCAM1 0.44 5.2 0.42 7.88e-7 Prostate cancer; TGCT cis rs912057 0.601 rs1294405 chr6:6737591 A/G cg06612196 chr6:6737390 NA 0.49 7.33 0.55 2.58e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs4478858 0.735 rs11436 chr1:31837320 T/C cg07478791 chr1:31886160 SERINC2 -0.51 -4.93 -0.41 2.55e-6 Alcohol dependence; TGCT cis rs6967414 0.786 rs6953825 chr7:6755624 A/C cg09896999 chr7:6746977 ZNF12 -0.59 -6.54 -0.51 1.45e-9 Hematocrit;Hemoglobin concentration; TGCT cis rs8062405 1.000 rs3088215 chr16:28853996 A/C cg09754948 chr16:28834200 ATXN2L 0.59 4.45 0.37 1.91e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2836974 0.897 rs1571709 chr21:40553980 T/C cg11890956 chr21:40555474 PSMG1 1.12 12.23 0.74 4.65e-23 Cognitive function; TGCT cis rs8017423 0.935 rs11159960 chr14:90740012 C/T cg04374321 chr14:90722782 PSMC1 -0.75 -7.3 -0.55 2.96e-11 Mortality in heart failure; TGCT cis rs2228479 0.867 rs62052187 chr16:89973071 G/A cg06558623 chr16:89946397 TCF25 0.49 6.18 0.49 8.5e-9 Skin colour saturation; TGCT cis rs6121246 0.567 rs6060295 chr20:30198473 C/T cg18721089 chr20:30220636 NA -0.64 -6.86 -0.52 2.84e-10 Mean corpuscular hemoglobin; TGCT cis rs908922 0.676 rs1538083 chr1:152517116 A/G cg20991723 chr1:152506922 NA 0.45 6.11 0.48 1.18e-8 Hair morphology; TGCT cis rs8177253 0.665 rs12639304 chr3:133441594 A/T cg11941060 chr3:133502564 NA -0.26 -5.43 -0.44 2.88e-7 Iron status biomarkers; TGCT cis rs12210905 0.688 rs72845030 chr6:27532643 A/G cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg22166914 chr1:53195759 ZYG11B -0.39 -6.57 -0.51 1.25e-9 Monocyte count; TGCT cis rs7584330 0.554 rs76408976 chr2:238384784 C/T cg14458575 chr2:238380390 NA 0.58 5.05 0.41 1.53e-6 Prostate cancer; TGCT cis rs7940866 0.838 rs10736592 chr11:130800572 C/T cg12179176 chr11:130786555 SNX19 0.63 6.32 0.49 4.39e-9 Schizophrenia; TGCT cis rs910316 0.967 rs4903293 chr14:75656568 A/G cg11812906 chr14:75593930 NEK9 -0.71 -6.83 -0.52 3.43e-10 Height; TGCT cis rs904251 0.772 rs10692 chr6:37450914 T/C cg25019722 chr6:37503610 NA -0.43 -5.02 -0.41 1.73e-6 Cognitive performance; TGCT cis rs9733 0.791 rs11204693 chr1:150647987 C/T cg13175981 chr1:150552382 MCL1 0.42 4.73 0.39 5.88e-6 Tonsillectomy; TGCT cis rs12477438 0.520 rs4851187 chr2:99745860 G/T cg15544633 chr2:99771531 LIPT1;TSGA10 -1.16 -18.76 -0.86 5.07e-38 Chronic sinus infection; TGCT cis rs12701220 0.894 rs13224488 chr7:1052353 C/A cg27454412 chr7:1067447 C7orf50 -0.48 -4.44 -0.37 1.98e-5 Bronchopulmonary dysplasia; TGCT cis rs80282103 0.618 rs56004802 chr10:1159187 C/T cg18964960 chr10:1102726 WDR37 1.06 4.57 0.38 1.15e-5 Glomerular filtration rate (creatinine); TGCT cis rs10782582 0.593 rs6675212 chr1:76230829 C/A cg22875332 chr1:76189707 ACADM -0.45 -4.97 -0.41 2.15e-6 Daytime sleep phenotypes; TGCT cis rs7258465 0.931 rs8107351 chr19:18612758 G/A cg06462663 chr19:18546047 ISYNA1 0.2 4.67 0.39 7.74e-6 Breast cancer; TGCT cis rs11025559 0.812 rs16906280 chr11:20472242 T/C cg19653624 chr11:20408972 PRMT3 -0.63 -4.88 -0.4 3.14e-6 Pursuit maintenance gain; TGCT cis rs13191362 1.000 rs73035023 chr6:163000927 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7937682 0.737 rs518294 chr11:111424716 A/T cg09085632 chr11:111637200 PPP2R1B -0.8 -8.33 -0.6 1.3e-13 Primary sclerosing cholangitis; TGCT cis rs7267979 1.000 rs4815407 chr20:25341478 G/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7726839 0.574 rs11134149 chr5:637277 A/G cg25482853 chr8:67687455 SGK3 1.13 10.6 0.69 4.48e-19 Obesity-related traits; TGCT trans rs2469997 0.925 rs2470015 chr8:120360969 T/C cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT cis rs13242816 0.881 rs13235183 chr7:116140149 G/T cg16553024 chr7:116138462 CAV2 -0.44 -5.38 -0.44 3.56e-7 P wave duration; TGCT trans rs1814175 0.935 rs1827017 chr11:49632592 C/G cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs854765 0.583 rs8075965 chr17:17853180 A/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.69 0.57 3.98e-12 Total body bone mineral density; TGCT cis rs853679 0.546 rs200948 chr6:27835272 T/C cg01031101 chr6:28227091 NKAPL -0.49 -4.66 -0.39 8.09e-6 Depression; TGCT cis rs7267979 0.966 rs4815414 chr20:25361701 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7659604 0.539 rs72680779 chr4:122797263 C/T cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.36 -0.43 3.84e-7 Type 2 diabetes; TGCT cis rs514406 0.861 rs503015 chr1:53254456 T/C cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs13191362 1.000 rs67487119 chr6:163102657 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.99 8.09 0.59 4.62e-13 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11098499 0.754 rs11098502 chr4:120252063 T/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs835154 1.000 rs835154 chr5:14876569 A/G cg14843632 chr5:14870594 ANKH -0.42 -6.25 -0.49 6e-9 Blood metabolite levels; TGCT cis rs7428 0.527 rs3184780 chr2:85549547 C/T cg03728395 chr2:85555865 TGOLN2 -0.29 -5.09 -0.42 1.32e-6 Ear protrusion; TGCT cis rs17401966 0.838 rs946501 chr1:10309580 C/G cg19773385 chr1:10388646 KIF1B -0.2 -4.5 -0.37 1.54e-5 Hepatocellular carcinoma; TGCT cis rs12971120 0.891 rs71359051 chr18:72169723 G/A cg25817165 chr18:72167213 CNDP2 -0.29 -5.11 -0.42 1.16e-6 Refractive error; TGCT cis rs9527 0.518 rs11191530 chr10:104800044 C/T cg15744005 chr10:104629667 AS3MT 0.55 4.63 0.38 9.04e-6 Arsenic metabolism; TGCT cis rs57994353 0.598 rs72775768 chr9:139324574 C/T cg13741927 chr9:139327495 INPP5E -0.28 -6.65 -0.51 8.17e-10 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs9910055 1.000 rs9895423 chr17:42285740 T/C cg13607699 chr17:42295918 UBTF 0.87 7.48 0.56 1.16e-11 Total body bone mineral density; TGCT cis rs9921338 0.923 rs17233387 chr16:11389048 C/T cg00044050 chr16:11439710 C16orf75 -0.63 -4.52 -0.38 1.45e-5 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs208520 0.690 rs3899423 chr6:66835285 A/G cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs4654899 0.758 rs6688147 chr1:21335894 A/G cg01072550 chr1:21505969 NA -0.55 -8.93 -0.63 4.73e-15 Superior frontal gyrus grey matter volume; TGCT cis rs7107174 1.000 rs10793302 chr11:78040961 C/T cg12700464 chr11:78128424 GAB2 -0.65 -4.75 -0.39 5.55e-6 Testicular germ cell tumor; TGCT cis rs9325144 0.505 rs1906262 chr12:38653605 A/G cg26384229 chr12:38710491 ALG10B 0.71 6.85 0.52 3.09e-10 Morning vs. evening chronotype; TGCT trans rs2727020 0.734 rs1164664 chr11:49295542 T/G cg11707556 chr5:10655725 ANKRD33B 0.38 6.8 0.52 3.89e-10 Coronary artery disease; TGCT cis rs2288884 0.943 rs75722407 chr19:52525242 C/T cg13540795 chr19:52551618 ZNF432 -0.56 -4.72 -0.39 6.33e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs2115630 0.691 rs8040066 chr15:85176465 G/C cg12501888 chr15:85177176 SCAND2 -0.49 -4.57 -0.38 1.14e-5 P wave terminal force; TGCT cis rs4886920 0.563 rs4442775 chr15:78079120 T/C cg25212270 chr15:78015279 NA -0.23 -4.87 -0.4 3.36e-6 Neuroticism; TGCT cis rs6988636 1.000 rs13260775 chr8:124190167 G/A cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs11098499 1.000 rs6849889 chr4:120186348 A/C cg09307838 chr4:120376055 NA 0.52 4.73 0.39 6.12e-6 Corneal astigmatism; TGCT cis rs12200560 0.505 rs211173 chr6:97070804 C/T cg06623918 chr6:96969491 KIAA0776 0.59 5.02 0.41 1.76e-6 Coronary heart disease; TGCT cis rs68170813 0.559 rs76646886 chr7:107034328 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs12519773 0.576 rs55971857 chr5:92441594 A/C cg18783429 chr5:92414398 NA 0.31 4.5 0.37 1.56e-5 Migraine; TGCT cis rs1372520 0.684 rs2619341 chr4:90741773 A/G cg14346243 chr4:90757452 SNCA -0.67 -5.64 -0.45 1.11e-7 Neuroticism; TGCT cis rs1552244 1.000 rs17032277 chr3:10077023 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs7811142 0.775 rs1636980 chr7:99938864 A/G cg00814883 chr7:100076585 TSC22D4 0.84 8.45 0.6 6.59e-14 Platelet count; TGCT cis rs509477 0.851 rs1941751 chr18:32577017 G/A cg23791764 chr18:32556832 MAPRE2 -0.63 -5.15 -0.42 9.82e-7 Cerebrospinal fluid AB1-42 levels; TGCT cis rs514406 0.505 rs835609 chr1:53170494 T/C cg25767906 chr1:53392781 SCP2 -0.46 -4.99 -0.41 2.03e-6 Monocyte count; TGCT cis rs7818688 0.697 rs61591488 chr8:95984955 C/T cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs12142240 0.698 rs10158236 chr1:46820896 G/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs8031584 0.918 rs61997140 chr15:31277312 A/G cg08704250 chr15:31115839 NA -0.35 -4.93 -0.4 2.6e-6 Huntington's disease progression; TGCT cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg08219700 chr8:58056026 NA 0.3 4.57 0.38 1.14e-5 Developmental language disorder (linguistic errors); TGCT cis rs10791323 0.593 rs2282604 chr11:133714672 A/G cg15485101 chr11:133734466 NA 0.35 4.84 0.4 3.75e-6 Childhood ear infection; TGCT cis rs10186029 0.680 rs1530238 chr2:213957928 G/C cg08319019 chr2:214017104 IKZF2 0.62 5.63 0.45 1.16e-7 Systemic sclerosis; TGCT cis rs9921338 0.961 rs72773834 chr16:11413293 G/A cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs1568889 0.838 rs3812738 chr11:28129982 C/A cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.14 0.71 2.18e-20 Bipolar disorder; TGCT cis rs7829975 0.511 rs2948286 chr8:8130160 A/G cg15556689 chr8:8085844 FLJ10661 0.82 7.77 0.57 2.59e-12 Mood instability; TGCT cis rs6460942 1.000 rs79659770 chr7:12326371 T/C cg06484146 chr7:12443880 VWDE -0.54 -4.55 -0.38 1.26e-5 Coronary artery disease; TGCT cis rs25422 0.938 rs62424176 chr6:118798602 T/C cg21191810 chr6:118973309 C6orf204 -0.36 -4.74 -0.39 5.8e-6 Renal cell carcinoma; TGCT cis rs6570726 0.846 rs6919684 chr6:145883801 A/G cg05347473 chr6:146136440 FBXO30 0.51 4.78 0.39 4.8e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10782582 0.593 rs11163915 chr1:76130199 C/T cg22875332 chr1:76189707 ACADM -0.54 -6.21 -0.49 7.36e-9 Daytime sleep phenotypes; TGCT cis rs6740322 1.000 rs6756736 chr2:43558743 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.38 -6.32 -0.49 4.21e-9 Coronary artery disease; TGCT trans rs62103177 0.608 rs59300126 chr18:77694439 C/A cg05926928 chr17:57297772 GDPD1 0.98 9.2 0.64 1.09e-15 Opioid sensitivity; TGCT cis rs9296092 0.517 rs55683509 chr6:33471077 A/G cg13560919 chr6:33536144 NA -0.22 -4.49 -0.37 1.6e-5 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs10197940 0.662 rs4467261 chr2:152281391 G/C cg06191203 chr2:152266755 RIF1 -0.71 -6.28 -0.49 5.14e-9 Lung cancer; TGCT cis rs1451375 0.698 rs1839740 chr7:50646280 C/T cg18232548 chr7:50535776 DDC 0.44 6.83 0.52 3.36e-10 Malaria; TGCT cis rs875971 0.767 rs1695815 chr7:65831344 A/G cg18876405 chr7:65276391 NA 0.32 4.89 0.4 3.11e-6 Aortic root size; TGCT cis rs2153535 0.601 rs7738877 chr6:8542230 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.03 0.41 1.69e-6 Motion sickness; TGCT cis rs7647973 0.626 rs4855882 chr3:49715354 G/T cg03060546 chr3:49711283 APEH 0.63 5.33 0.43 4.5e-7 Menarche (age at onset); TGCT cis rs709400 0.628 rs7146506 chr14:103924477 A/G cg12935359 chr14:103987150 CKB -0.35 -5.38 -0.44 3.5e-7 Body mass index; TGCT cis rs1799949 1.000 rs4793190 chr17:41200109 T/C cg23758822 chr17:41437982 NA 0.75 7.03 0.53 1.22e-10 Menopause (age at onset); TGCT cis rs3818285 0.632 rs536343 chr10:111632879 T/C cg00817464 chr10:111662876 XPNPEP1 0.32 5.57 0.45 1.51e-7 Superior crus of antihelix expression; TGCT cis rs853679 0.517 rs56310871 chr6:28044482 A/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Depression; TGCT cis rs12579753 0.833 rs1922566 chr12:82135030 T/C cg07988820 chr12:82153109 PPFIA2 -0.68 -7.32 -0.55 2.7e-11 Resting heart rate; TGCT cis rs6554196 0.686 rs6554195 chr4:55500714 G/T cg02821500 chr4:54931072 CHIC2 0.48 4.71 0.39 6.54e-6 Monocyte count; TGCT cis rs9611565 0.592 rs5758406 chr22:42076641 A/G cg06634786 chr22:41940651 POLR3H 0.9 9.03 0.63 2.7e-15 Vitiligo; TGCT cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg07424592 chr7:64974309 NA -1.26 -7.79 -0.57 2.25e-12 Diabetic kidney disease; TGCT cis rs3008870 0.583 rs3008892 chr1:67373558 A/T cg08660285 chr1:67390436 MIER1;WDR78 0.93 8.01 0.58 7.28e-13 Lymphocyte percentage of white cells; TGCT cis rs2758596 0.850 rs2241110 chr1:156172487 A/G cg24450063 chr1:156163899 SLC25A44 0.79 4.58 0.38 1.11e-5 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs6665290 0.935 rs17600627 chr1:227201449 A/G cg10327440 chr1:227177885 CDC42BPA -0.98 -20.12 -0.87 7.08e-41 Myeloid white cell count; TGCT cis rs4555082 0.794 rs2735829 chr14:105708472 C/T cg01266790 chr14:105781312 PACS2 0.55 4.5 0.37 1.57e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs514406 0.708 rs546334 chr1:53326210 T/C cg16325326 chr1:53192061 ZYG11B 0.56 6.18 0.49 8.46e-9 Monocyte count; TGCT cis rs17345786 0.798 rs1609159 chr3:101275902 A/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.64 6.08 0.48 1.36e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 0.901 rs35823062 chr7:65965821 A/G cg07424592 chr7:64974309 NA 1.3 8.23 0.59 2.19e-13 Diabetic kidney disease; TGCT cis rs9341808 0.700 rs12215236 chr6:80975058 A/T cg08355045 chr6:80787529 NA 0.29 4.98 0.41 2.04e-6 Sitting height ratio; TGCT cis rs10504229 0.953 rs114806125 chr8:58182416 C/T cg24829409 chr8:58192753 C8orf71 -0.52 -5.02 -0.41 1.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs12049351 0.774 rs6661924 chr1:229642740 G/T cg12130225 chr1:229698885 NA 0.39 4.6 0.38 1.02e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs763121 0.853 rs5750664 chr22:39072769 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs1129187 0.935 rs9462859 chr6:42946943 G/A cg27588902 chr6:42928151 GNMT -0.5 -5.92 -0.47 2.93e-8 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.01 0.41 1.86e-6 Prudent dietary pattern; TGCT cis rs116095464 0.558 rs9312977 chr5:221916 G/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs3733585 0.699 rs6815001 chr4:9958662 G/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.830 rs115279324 chr4:99042114 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.94 0.47 2.68e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs651907 0.535 rs34161138 chr3:101510388 T/C cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.4 -0.5 2.91e-9 Colorectal cancer; TGCT cis rs765787 0.530 rs4774550 chr15:45542312 C/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs6952808 0.792 rs2056478 chr7:1953897 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.51 -0.44 2e-7 Bipolar disorder and schizophrenia; TGCT cis rs35306767 0.715 rs1250891 chr10:1040159 G/C cg20503657 chr10:835505 NA 0.62 6.9 0.53 2.4e-10 Eosinophil percentage of granulocytes; TGCT cis rs71435601 0.628 rs4560142 chr2:21383717 A/G cg25035485 chr2:21266500 APOB -0.51 -4.48 -0.37 1.64e-5 Cholesterol, total; TGCT cis rs7412746 0.658 rs7526489 chr1:150726238 C/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.57 0.38 1.15e-5 Melanoma; TGCT cis rs2235642 0.750 rs2755185 chr16:1645827 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.27 -4.53 -0.38 1.39e-5 Coronary artery disease; TGCT trans rs1814175 0.817 rs4881648 chr11:49812901 A/G cg11707556 chr5:10655725 ANKRD33B -0.37 -7.35 -0.55 2.38e-11 Height; TGCT cis rs709400 0.930 rs2274268 chr14:104029378 C/G cg26031613 chr14:104095156 KLC1 1.15 14.5 0.79 1.83e-28 Body mass index; TGCT cis rs8050907 1.000 rs7195763 chr16:4649300 C/G cg02183435 chr16:5121731 ALG1 -0.85 -4.44 -0.37 1.99e-5 Obesity-related traits; TGCT cis rs1552244 0.882 rs68153882 chr3:10013110 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.53 0.44 1.8e-7 Alzheimer's disease; TGCT cis rs1552244 1.000 rs57631744 chr3:10118962 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs2075371 0.796 rs12672752 chr7:134007382 C/T cg11752832 chr7:134001865 SLC35B4 0.72 6.44 0.5 2.4e-9 Mean platelet volume; TGCT cis rs6906287 0.625 rs9320649 chr6:118693665 A/G cg21191810 chr6:118973309 C6orf204 -0.27 -4.5 -0.37 1.52e-5 Electrocardiographic conduction measures; TGCT cis rs6840360 0.762 rs62327352 chr4:152670780 C/A cg22705602 chr4:152727874 NA -0.25 -4.48 -0.37 1.64e-5 Intelligence (multi-trait analysis); TGCT cis rs9653442 0.564 rs12712071 chr2:100793876 G/A cg07810366 chr2:100720526 AFF3 -0.36 -5.22 -0.42 7.26e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7429990 0.965 rs62260764 chr3:47990500 G/C cg11946769 chr3:48343235 NME6 0.59 4.5 0.37 1.57e-5 Educational attainment (years of education); TGCT cis rs2836974 0.897 rs35064900 chr21:40555492 A/G cg06238570 chr21:40685208 BRWD1 0.76 7.13 0.54 7.21e-11 Cognitive function; TGCT cis rs4987668 0.786 rs4252379 chr7:142629654 A/C cg21621906 chr7:142494914 NA -0.87 -4.51 -0.38 1.49e-5 Cancer; TGCT cis rs9430161 0.579 rs11121667 chr1:11038476 C/T cg02454025 chr1:11042201 C1orf127 0.97 12.9 0.76 1.15e-24 Ewing sarcoma; TGCT cis rs12142240 0.698 rs6690075 chr1:46819848 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs11719291 0.504 rs34571182 chr3:49209057 T/A cg00383909 chr3:49044727 WDR6 1.28 6.68 0.51 7.04e-10 Cognitive function; TGCT cis rs8180040 0.764 rs11712716 chr3:47193432 T/C cg27129171 chr3:47204927 SETD2 0.75 9.86 0.66 2.82e-17 Colorectal cancer; TGCT cis rs7954584 0.531 rs11043271 chr12:122394921 A/C cg22618164 chr12:122356400 WDR66 0.69 6.49 0.5 1.83e-9 Mean corpuscular volume; TGCT cis rs2836974 0.899 rs68004583 chr21:40659587 T/C cg17971929 chr21:40555470 PSMG1 0.97 9.48 0.65 2.31e-16 Cognitive function; TGCT cis rs2120019 1.000 rs1867146 chr15:75354971 C/G cg11632617 chr15:75315747 PPCDC -0.33 -4.59 -0.38 1.07e-5 Blood trace element (Zn levels); TGCT cis rs208515 0.592 rs10944862 chr6:66674215 C/T cg07460842 chr6:66804631 NA 0.88 9.35 0.64 4.63e-16 Exhaled nitric oxide levels; TGCT cis rs6964587 0.934 rs7811328 chr7:91720931 A/T cg17063962 chr7:91808500 NA 0.86 9.47 0.65 2.39e-16 Breast cancer; TGCT cis rs13188771 0.527 rs408727 chr5:100877888 T/C cg18665594 chr5:101119420 NA 0.44 4.49 0.37 1.62e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7829975 0.688 rs7817376 chr8:8380530 C/T cg15556689 chr8:8085844 FLJ10661 -0.67 -6.21 -0.49 7.49e-9 Mood instability; TGCT cis rs12142240 0.698 rs17357683 chr1:46815378 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs56036086 1.000 rs56036086 chr22:50628996 G/A cg01548456 chr22:50352384 NA 0.37 4.82 0.4 4.15e-6 Platelet count;Plateletcrit; TGCT cis rs1865760 0.964 rs9379802 chr6:25933898 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.63 6.06 0.48 1.52e-8 Height; TGCT trans rs74910095 0.786 rs11957329 chr5:62936327 G/C cg02938449 chr2:220419364 OBSL1 0.8 6.75 0.52 4.95e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs76473307 1.000 rs77855067 chr20:57378801 G/C cg06163629 chr20:57414884 GNASAS;GNAS -0.7 -4.61 -0.38 1.01e-5 Chronic lymphocytic leukemia; TGCT cis rs2016266 0.859 rs56225815 chr12:53740090 C/G cg16917193 chr12:54089295 NA -0.7 -4.68 -0.39 7.49e-6 Bone mineral density (spine);Bone mineral density; TGCT cis rs4727027 0.901 rs10952792 chr7:148760501 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.99 0.41 2.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs951366 0.903 rs708723 chr1:205739266 C/T cg14159672 chr1:205819179 PM20D1 0.42 4.56 0.38 1.19e-5 Menarche (age at onset); TGCT cis rs13336428 0.730 rs3946124 chr16:1525779 A/G cg08008072 chr16:1524255 CLCN7 0.62 9.34 0.64 5.05e-16 Bone mineral density; TGCT cis rs2836974 0.965 rs2836967 chr21:40639102 T/G cg11890956 chr21:40555474 PSMG1 1.09 11.95 0.73 2.27e-22 Cognitive function; TGCT cis rs6725041 0.819 rs939226 chr2:213088846 A/G cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs10992471 0.603 rs1980848 chr9:95248571 A/G cg13798575 chr9:95087839 CENPP;NOL8 0.62 5.72 0.46 7.5e-8 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs9929218 0.551 rs3785133 chr16:68728611 C/T cg01251360 chr16:68772225 CDH1 -0.27 -4.92 -0.4 2.66e-6 Colorectal cancer; TGCT trans rs621559 0.636 rs632866 chr1:43670624 C/A cg19324027 chr2:74699582 MRPL53 -0.87 -6.75 -0.52 5.12e-10 Telomere length; TGCT cis rs2115630 1.000 rs2115630 chr15:85364516 C/T cg11189052 chr15:85197271 WDR73 -0.63 -5.93 -0.47 2.84e-8 P wave terminal force; TGCT cis rs478304 0.651 rs78412025 chr11:65495696 T/C cg17480646 chr11:65405466 SIPA1 -0.57 -6.98 -0.53 1.61e-10 Acne (severe); TGCT cis rs7147624 0.683 rs8017258 chr14:66231017 C/G cg03016385 chr14:66212404 NA 0.51 5.72 0.46 7.58e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs427394 0.802 rs274692 chr5:6734625 C/T cg10857441 chr5:6722123 POLS -0.32 -7.93 -0.58 1.08e-12 Menopause (age at onset); TGCT cis rs7027203 1.000 rs7854820 chr9:96526027 A/G cg13679303 chr9:96623674 NA 0.65 10.13 0.67 6.09e-18 DNA methylation (variation); TGCT cis rs2243480 1.000 rs316326 chr7:65609453 T/C cg18252515 chr7:66147081 NA -1.2 -7.83 -0.58 1.89e-12 Diabetic kidney disease; TGCT cis rs881375 0.631 rs2416808 chr9:123706283 G/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.44 4.73 0.39 6.09e-6 Rheumatoid arthritis; TGCT cis rs4919694 1.000 rs76255497 chr10:104651955 T/C cg04362960 chr10:104952993 NT5C2 1.03 6.95 0.53 1.83e-10 Arsenic metabolism; TGCT cis rs4711350 0.862 rs597723 chr6:33694079 C/T cg18005901 chr6:33739558 LEMD2 0.44 4.73 0.39 6.11e-6 Schizophrenia; TGCT cis rs10788264 0.569 rs7089468 chr10:124019052 T/C cg09507567 chr10:124027408 NA 0.39 5.89 0.47 3.35e-8 Total body bone mineral density; TGCT cis rs7552404 0.731 rs61770552 chr1:76373050 T/C cg10523679 chr1:76189770 ACADM 0.84 7.32 0.55 2.77e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2032447 0.802 rs198853 chr6:26104096 T/C cg07061783 chr6:25882402 NA 0.58 5.62 0.45 1.21e-7 Intelligence (multi-trait analysis); TGCT cis rs554111 0.637 rs604659 chr1:21043913 T/C cg24117274 chr1:21945805 RAP1GAP 0.31 4.72 0.39 6.35e-6 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs79057730 0.599 rs9458 chr7:825494 A/G cg11064039 chr7:766100 PRKAR1B;HEATR2 -0.75 -5.93 -0.47 2.84e-8 Initial pursuit acceleration; TGCT cis rs727505 0.954 rs2239532 chr7:124405676 A/C cg23710748 chr7:124431027 NA -0.27 -4.82 -0.4 4.05e-6 Lewy body disease; TGCT cis rs11107903 1.000 rs12830164 chr12:95514233 G/T cg10621809 chr12:95840313 NA 0.7 4.61 0.38 9.89e-6 Coronary artery disease; TGCT cis rs4819052 0.851 rs2838840 chr21:46668494 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.63 5.12 0.42 1.11e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs629535 0.814 rs506931 chr8:70068129 T/G cg21567404 chr3:27674614 NA 0.57 9.11 0.63 1.82e-15 Dupuytren's disease; TGCT cis rs9300255 0.770 rs28683528 chr12:123845351 C/T cg00376283 chr12:123451042 ABCB9 -0.65 -4.57 -0.38 1.17e-5 Neutrophil percentage of white cells; TGCT cis rs1729951 0.575 rs1682356 chr3:136692037 T/C cg21827317 chr3:136751795 NA 0.4 5.61 0.45 1.28e-7 Neuroticism; TGCT cis rs9611519 1.000 rs5758268 chr22:41622419 A/T cg13695892 chr22:41940480 POLR3H -0.51 -4.68 -0.39 7.46e-6 Neuroticism; TGCT cis rs909674 0.731 rs4821897 chr22:39835587 A/G cg01416388 chr22:39784598 NA -0.75 -6.8 -0.52 3.9e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs13217239 0.646 rs35691005 chr6:26972070 A/G cg26531700 chr6:26746687 NA 0.68 6.79 0.52 4.1e-10 Schizophrenia; TGCT cis rs7975161 0.640 rs4477504 chr12:104710465 T/C cg25273343 chr12:104657179 TXNRD1 -0.34 -4.82 -0.4 4.16e-6 Toenail selenium levels; TGCT cis rs514406 0.798 rs504816 chr1:53307957 T/G cg08736216 chr1:53307985 ZYG11A -0.28 -5.38 -0.44 3.57e-7 Monocyte count; TGCT cis rs11190604 1.000 rs2495747 chr10:102328247 C/T cg16342193 chr10:102329863 NA -0.42 -5.39 -0.44 3.47e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs929596 0.785 rs11695484 chr2:234654449 A/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.34 -5.3 -0.43 5.14e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs78456975 0.527 rs10206020 chr2:1557927 A/G cg12573674 chr2:1569213 NA -0.45 -4.76 -0.39 5.37e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7216064 1.000 rs62084251 chr17:65878736 G/A cg12091567 chr17:66097778 LOC651250 -0.83 -6.49 -0.5 1.9e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs3782455 1.000 rs117171899 chr12:114403070 G/A cg23502203 chr12:113549970 RASAL1 -0.55 -4.92 -0.4 2.7e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs853679 0.546 rs200948 chr6:27835272 T/C cg08798685 chr6:27730294 NA -0.34 -4.69 -0.39 7.2e-6 Depression; TGCT trans rs941408 1.000 rs1736177 chr19:2791624 C/T cg22153745 chr1:153894579 GATAD2B -0.65 -7.5 -0.56 1.08e-11 Total cholesterol levels; TGCT cis rs7959452 0.530 rs12811632 chr12:69755003 G/A cg20891283 chr12:69753455 YEATS4 0.83 8.61 0.61 2.77e-14 Blood protein levels; TGCT cis rs3008870 0.959 rs3008852 chr1:67383416 G/A cg03991309 chr1:68237761 GNG12 0.27 4.68 0.39 7.28e-6 Lymphocyte percentage of white cells; TGCT cis rs682748 0.846 rs13187032 chr5:17135535 A/G cg23987134 chr5:17158319 LOC285696 -0.21 -5.11 -0.42 1.17e-6 Hippocampal atrophy; TGCT cis rs3617 0.573 rs9810807 chr3:52924227 C/T cg10802521 chr3:52805072 NEK4 0.58 6.47 0.5 2.07e-9 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1997103 0.863 rs6956287 chr7:55415107 T/C cg17469321 chr7:55412551 NA 0.61 5.91 0.47 3.03e-8 QRS interval (sulfonylurea treatment interaction); TGCT cis rs11085466 1.000 rs73552468 chr19:21772097 G/A cg01048962 chr19:21646470 NA -0.57 -4.49 -0.37 1.63e-5 Colorectal or endometrial cancer; TGCT cis rs617219 0.671 rs2220839 chr5:78603510 T/A cg05890484 chr5:78407552 BHMT -0.34 -4.65 -0.39 8.5e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs9611565 0.592 rs5758427 chr22:42099688 A/G cg06481639 chr22:41940642 POLR3H 0.71 6.48 0.5 1.95e-9 Vitiligo; TGCT cis rs3774830 0.714 rs7685158 chr4:5462776 C/T cg26943120 chr4:5472116 STK32B 0.23 5.16 0.42 9.66e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6939532 0.761 rs3799378 chr6:26404374 C/T cg05738196 chr6:26577821 NA 0.5 4.62 0.38 9.34e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs2032447 0.802 rs12346 chr6:26097046 T/C cg12310025 chr6:25882481 NA -0.7 -6.44 -0.5 2.4e-9 Intelligence (multi-trait analysis); TGCT cis rs2230307 0.536 rs11166407 chr1:100637708 C/T cg24955406 chr1:100503596 HIAT1 0.75 5.33 0.43 4.41e-7 Carotid intima media thickness; TGCT cis rs7666738 0.515 rs13131874 chr4:98779183 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.73 0.46 7.24e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6095298 0.595 rs6095319 chr20:47446556 G/A cg12307787 chr20:48099359 KCNB1 0.44 4.67 0.39 7.75e-6 Intelligence (multi-trait analysis); TGCT cis rs2836633 0.929 rs764482 chr21:40033661 C/G cg12884169 chr21:40033163 ERG 0.47 4.98 0.41 2.04e-6 Coronary artery disease; TGCT cis rs2239547 0.657 rs4687672 chr3:52880543 G/A cg11645453 chr3:52864694 ITIH4 0.35 5.88 0.47 3.57e-8 Schizophrenia; TGCT cis rs7567389 0.710 rs72848618 chr2:128135325 A/C cg09760422 chr2:128146352 NA 0.34 4.52 0.38 1.41e-5 Self-rated health; TGCT cis rs13217239 0.646 rs11756275 chr6:27007113 A/C cg05738196 chr6:26577821 NA -0.48 -4.57 -0.38 1.14e-5 Schizophrenia; TGCT cis rs12682352 0.602 rs4841044 chr8:8664940 A/G cg08975724 chr8:8085496 FLJ10661 -0.51 -4.48 -0.37 1.68e-5 Neuroticism; TGCT trans rs7615952 0.741 rs13314845 chr3:125644782 C/T cg07211511 chr3:129823064 LOC729375 -0.48 -8.02 -0.58 6.91e-13 Blood pressure (smoking interaction); TGCT cis rs1862618 0.853 rs252921 chr5:56137787 G/A cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs7647973 0.925 rs6446256 chr3:49224210 A/G cg07636037 chr3:49044803 WDR6 0.63 5.09 0.42 1.27e-6 Menarche (age at onset); TGCT cis rs1008375 1.000 rs1008374 chr4:17683219 G/A cg10189774 chr4:17578691 LAP3 0.52 4.87 0.4 3.28e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2147959 0.771 rs6426505 chr1:228701102 C/G cg22700015 chr1:228743131 NA -0.62 -5.1 -0.42 1.23e-6 Adult asthma; TGCT cis rs1577917 0.771 rs4383777 chr6:86435960 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.63 5.39 0.44 3.43e-7 Response to antipsychotic treatment; TGCT cis rs13242816 1.000 rs73208106 chr7:116173263 G/A cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs4925325 0.956 rs1776263 chr20:60515820 A/G cg16423285 chr20:60520624 NA -0.76 -9.26 -0.64 7.88e-16 Obesity-related traits; TGCT cis rs58688157 0.960 rs1061502 chr11:614318 T/C cg16486109 chr11:613632 IRF7 0.36 5.26 0.43 6.02e-7 Systemic lupus erythematosus; TGCT cis rs2996428 0.667 rs2368534 chr1:3740640 C/T cg10555106 chr1:3691387 LOC388588 0.33 4.74 0.39 5.85e-6 Red cell distribution width; TGCT cis rs13242816 1.000 rs3807995 chr7:116197976 C/T cg02799643 chr7:116139180 CAV2 -0.43 -5.45 -0.44 2.59e-7 P wave duration; TGCT trans rs931812 0.825 rs13271753 chr8:101895491 T/C cg20993868 chr7:22813445 NA 0.42 9.03 0.63 2.75e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg10117171 chr1:25599238 RHD -0.36 -5.95 -0.47 2.58e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs9527 0.590 rs6584537 chr10:104778267 C/G cg04362960 chr10:104952993 NT5C2 0.65 5.54 0.45 1.73e-7 Arsenic metabolism; TGCT cis rs10504229 1.000 rs56344560 chr8:58180626 C/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.764 rs17259257 chr4:119778889 C/T cg21605333 chr4:119757512 SEC24D 1.55 8.04 0.59 6.15e-13 Cannabis dependence symptom count; TGCT cis rs11711311 0.712 rs11718013 chr3:113341661 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.69 -5.81 -0.46 5.03e-8 IgG glycosylation; TGCT cis rs12048904 0.619 rs12239082 chr1:101330077 G/T cg00063077 chr1:101360652 SLC30A7;EXTL2 -0.82 -8.31 -0.6 1.42e-13 Multiple sclerosis; TGCT cis rs7829975 0.577 rs79495969 chr8:8545250 G/A cg15556689 chr8:8085844 FLJ10661 -0.53 -4.5 -0.37 1.53e-5 Mood instability; TGCT cis rs11578119 0.933 rs11587811 chr1:170482352 C/T cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs6740322 0.748 rs6727631 chr2:43470408 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.4 -6.2 -0.49 7.78e-9 Coronary artery disease; TGCT cis rs651907 0.967 rs694936 chr3:101587793 A/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.46 4.83 0.4 3.97e-6 Colorectal cancer; TGCT cis rs11578119 0.902 rs4508077 chr1:170461981 A/G cg09767346 chr1:170501363 GORAB -0.68 -5.41 -0.44 3.18e-7 Male-pattern baldness; TGCT cis rs459571 0.959 rs378740 chr9:136890876 C/A cg13789015 chr9:136890014 NCRNA00094 0.39 7.2 0.54 5.07e-11 Platelet distribution width; TGCT cis rs739496 0.843 rs12369009 chr12:112019799 G/T cg10833066 chr12:111807467 FAM109A -0.37 -5.62 -0.45 1.19e-7 Platelet count; TGCT cis rs6089829 1.000 rs6089829 chr20:61669036 C/T cg08564027 chr20:61660810 NA -0.37 -6.57 -0.51 1.25e-9 Prostate cancer (SNP x SNP interaction); TGCT cis rs2762353 0.779 rs1408273 chr6:25840946 C/T cg03517284 chr6:25882590 NA 0.6 6.28 0.49 5.11e-9 Blood metabolite levels; TGCT cis rs2115536 1.000 rs2115536 chr15:80194247 C/T cg00225070 chr15:80189496 MTHFS 0.61 5.63 0.45 1.16e-7 Eosinophil counts;Eosinophil percentage of white cells;Sum eosinophil basophil counts;Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT trans rs1496653 0.602 rs35990123 chr3:23397104 C/T cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs151997 0.671 rs27907 chr5:50193797 C/G cg06027927 chr5:50259733 NA 0.56 5.78 0.46 5.72e-8 Callous-unemotional behaviour; TGCT cis rs2046867 0.908 rs9811830 chr3:72809591 A/G cg25664220 chr3:72788482 NA -0.53 -6.81 -0.52 3.8e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs35146811 0.695 rs1618851 chr7:99810643 T/G cg13334819 chr7:99746414 C7orf59 0.74 6.31 0.49 4.4e-9 Coronary artery disease; TGCT cis rs4925386 0.840 rs8124907 chr20:60913127 A/G cg06026331 chr20:60912101 LAMA5 0.37 6.37 0.5 3.35e-9 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs5750830 0.594 rs1010170 chr22:39778327 C/T cg11247378 chr22:39784982 NA 0.7 9.18 0.64 1.19e-15 Intelligence (multi-trait analysis); TGCT cis rs2456568 0.741 rs10831137 chr11:93636912 C/T cg16099599 chr11:93583650 C11orf90 -0.4 -5.12 -0.42 1.14e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs926938 0.563 rs360586 chr1:115467489 A/G cg12756093 chr1:115239321 AMPD1 0.41 6.44 0.5 2.37e-9 Autism; TGCT cis rs9810089 0.903 rs7427564 chr3:136274435 G/A cg12473912 chr3:136751656 NA 0.34 4.86 0.4 3.54e-6 Gestational age at birth (child effect); TGCT cis rs4862750 0.914 rs10027250 chr4:187873460 T/C cg03452623 chr4:187889614 NA -0.36 -5.36 -0.43 3.84e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs1865760 1.000 rs7739966 chr6:25906040 T/C cg17042849 chr6:26104293 HIST1H4C -0.52 -4.68 -0.39 7.33e-6 Height; TGCT cis rs6951245 0.554 rs58210047 chr7:1149381 G/A cg09177884 chr7:1199841 ZFAND2A -0.71 -5.64 -0.45 1.1e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs116095464 1.000 rs28416084 chr5:217640 G/A cg22857025 chr5:266934 NA -0.34 -6.6 -0.51 1.09e-9 Breast cancer; TGCT cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.75 5.41 0.44 3.09e-7 Platelet count; TGCT cis rs6728642 0.908 rs13400545 chr2:97871626 A/G cg26665480 chr2:98280029 ACTR1B -0.97 -5.19 -0.42 8.35e-7 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs9399135 0.967 rs1041481 chr6:135335063 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs17197710 0.673 rs3736101 chr11:47306628 G/A cg13308137 chr11:47528955 CUGBP1 0.4 5.38 0.44 3.58e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs35160687 0.901 rs6713456 chr2:86507653 T/A cg03171300 chr2:86307199 POLR1A 0.3 4.93 0.4 2.61e-6 Night sleep phenotypes; TGCT cis rs13108904 0.870 rs11721789 chr4:1254414 C/A cg00684032 chr4:1343700 KIAA1530 0.22 4.82 0.4 4.11e-6 Obesity-related traits; TGCT cis rs35160687 0.901 rs12714180 chr2:86525323 G/T cg03171300 chr2:86307199 POLR1A 0.32 5.56 0.45 1.61e-7 Night sleep phenotypes; TGCT cis rs13082711 0.554 rs674798 chr3:27332302 G/T cg02860705 chr3:27208620 NA 0.34 5.58 0.45 1.43e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7582180 0.845 rs11683088 chr2:100920667 C/T cg08017756 chr2:100939284 LONRF2 -0.32 -5.4 -0.44 3.2e-7 Intelligence (multi-trait analysis); TGCT cis rs67311347 0.911 rs9849224 chr3:40392562 T/C cg17264618 chr3:40429014 ENTPD3 0.31 4.65 0.39 8.38e-6 Renal cell carcinoma; TGCT cis rs875971 0.662 rs448725 chr7:65514628 A/G cg11764359 chr7:65958608 NA 0.54 4.66 0.39 7.88e-6 Aortic root size; TGCT cis rs12478296 1.000 rs7420157 chr2:243005204 G/A cg06360820 chr2:242988706 NA -0.64 -5.35 -0.43 4.15e-7 Obesity-related traits; TGCT cis rs9916302 0.904 rs612194 chr17:37442707 T/A cg07936489 chr17:37558343 FBXL20 0.62 4.91 0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs4499344 0.633 rs259229 chr19:33134425 A/G cg26639809 chr19:33781782 NA -0.22 -4.59 -0.38 1.08e-5 Mean platelet volume; TGCT cis rs1913185 0.787 rs59850864 chr3:145829162 C/G cg26283496 chr3:146269126 NA 0.38 4.61 0.38 9.81e-6 Obesity-related traits; TGCT cis rs13202913 0.779 rs9383896 chr6:151768495 A/G cg03627880 chr6:151815985 C6orf97 -0.73 -5.42 -0.44 2.92e-7 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs4665809 1.000 rs6729080 chr2:26301282 G/A cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs7666738 0.791 rs13125277 chr4:99009922 T/G cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs682748 0.846 rs62347963 chr5:17133766 G/A cg23987134 chr5:17158319 LOC285696 -0.21 -5.11 -0.42 1.17e-6 Hippocampal atrophy; TGCT cis rs4820539 1.000 rs3788347 chr22:23467804 G/A cg14186256 chr22:23484241 RTDR1 0.98 11.79 0.73 5.47e-22 Bone mineral density; TGCT cis rs7095607 1.000 rs7094885 chr10:69953817 T/C cg18986048 chr10:69913749 MYPN 0.46 4.93 0.41 2.54e-6 Lung function (FVC); TGCT cis rs6089829 0.962 rs4809455 chr20:61660781 G/C cg02380750 chr20:61661411 NA 0.34 6.02 0.48 1.86e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7000551 0.663 rs7827093 chr8:22334610 A/G cg12081754 chr8:22256438 SLC39A14 0.3 4.97 0.41 2.16e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6558174 0.714 rs17674754 chr8:22533388 A/G cg03733263 chr8:22462867 KIAA1967 0.61 4.45 0.37 1.85e-5 Breast cancer; TGCT cis rs9467773 0.620 rs2504571 chr6:26643435 C/T cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.79e-6 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.649 rs5751108 chr22:41858035 T/C cg17554472 chr22:41940697 POLR3H 0.48 4.95 0.41 2.39e-6 Vitiligo; TGCT cis rs4911259 0.552 rs13038881 chr20:31468113 T/C cg13636640 chr20:31349939 DNMT3B -0.89 -9.83 -0.66 3.33e-17 Inflammatory bowel disease; TGCT cis rs2562456 0.833 rs516519 chr19:21481532 C/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.47 -0.37 1.76e-5 Pain; TGCT cis rs7178572 0.633 rs907369 chr15:77843560 A/G cg22256960 chr15:77711686 NA -0.82 -7.51 -0.56 1.03e-11 Type 2 diabetes; TGCT cis rs9291683 0.595 rs13145442 chr4:10037261 C/A cg00071950 chr4:10020882 SLC2A9 0.68 8.83 0.62 8.22e-15 Bone mineral density; TGCT cis rs6545883 0.894 rs9677047 chr2:61585295 C/G cg15711740 chr2:61764176 XPO1 0.54 4.61 0.38 9.77e-6 Tuberculosis; TGCT cis rs7267979 1.000 rs6115159 chr20:25350944 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7959452 0.535 rs7135092 chr12:69658330 T/C cg20891283 chr12:69753455 YEATS4 0.66 6.37 0.5 3.41e-9 Blood protein levels; TGCT cis rs28386778 0.769 rs6504179 chr17:61812995 T/G cg06873352 chr17:61820015 STRADA 0.5 5.28 0.43 5.67e-7 Prudent dietary pattern; TGCT cis rs2120019 1.000 rs60425110 chr15:75333000 T/A cg11632617 chr15:75315747 PPCDC -0.3 -4.47 -0.37 1.71e-5 Blood trace element (Zn levels); TGCT cis rs10504229 0.817 rs60646469 chr8:58195348 T/C cg21724239 chr8:58056113 NA 0.39 4.79 0.39 4.76e-6 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.644 rs1855127 chr1:53199594 A/G cg25767906 chr1:53392781 SCP2 0.46 5.17 0.42 8.95e-7 Monocyte count; TGCT cis rs854765 0.964 rs12943202 chr17:17994332 T/A cg09796270 chr17:17721594 SREBF1 -0.26 -5.08 -0.41 1.37e-6 Total body bone mineral density; TGCT trans rs4759375 0.748 rs596940 chr12:123560731 T/C cg08426444 chr8:73164019 NA 1.17 6.72 0.52 5.74e-10 HDL cholesterol; TGCT cis rs6815814 0.898 rs5743562 chr4:38806096 T/C cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs10465746 0.935 rs35946036 chr1:84438991 A/G cg10977910 chr1:84465055 TTLL7 0.65 6.54 0.51 1.44e-9 Obesity-related traits; TGCT cis rs12142240 0.698 rs1475390 chr1:46816340 A/G cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs9611565 0.729 rs203319 chr22:41914593 C/T cg06634786 chr22:41940651 POLR3H -0.79 -7.87 -0.58 1.54e-12 Vitiligo; TGCT trans rs7726839 0.540 rs7434 chr5:660804 A/G cg25482853 chr8:67687455 SGK3 -1.19 -10.67 -0.69 2.93e-19 Obesity-related traits; TGCT cis rs875971 1.000 rs875971 chr7:65617595 A/G cg11764359 chr7:65958608 NA -0.58 -5.05 -0.41 1.53e-6 Aortic root size; TGCT cis rs617219 0.671 rs2220839 chr5:78603510 T/A cg23514016 chr5:78407564 BHMT -0.31 -4.82 -0.4 4.11e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6087990 0.735 rs2889703 chr20:31379184 C/A cg13636640 chr20:31349939 DNMT3B 0.94 12.29 0.74 3.46e-23 Ulcerative colitis; TGCT cis rs2019137 0.560 rs7421852 chr2:113990261 G/A cg02675527 chr2:114030824 PAX8;LOC440839 -0.51 -6.62 -0.51 9.58e-10 Lymphocyte counts; TGCT cis rs11578119 0.933 rs12405323 chr1:170418964 G/A cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.66e-8 Male-pattern baldness; TGCT cis rs172166 0.538 rs149956 chr6:28036251 G/A cg13525197 chr6:28411240 ZSCAN23 -0.46 -4.5 -0.37 1.56e-5 Cardiac Troponin-T levels; TGCT cis rs1215050 0.605 rs10018404 chr4:98610830 A/C cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT trans rs931812 0.964 rs2102290 chr8:101919844 G/C cg20993868 chr7:22813445 NA 0.35 7.72 0.57 3.35e-12 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs9368481 0.761 rs7775041 chr6:27009512 T/A cg26531700 chr6:26746687 NA -0.54 -4.78 -0.39 4.9100000000000004e-06 Autism spectrum disorder or schizophrenia; TGCT cis rs6670062 0.536 rs1771941 chr1:247410614 G/A cg01868367 chr1:247372405 NA 0.27 4.62 0.38 9.47e-6 Trans fatty acid levels; TGCT trans rs7618501 0.633 rs4688758 chr3:50028385 G/A cg21659725 chr3:3221576 CRBN 0.76 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.735 rs7811662 chr7:99792608 A/G cg22906224 chr7:99728672 NA 0.49 4.45 0.37 1.88e-5 Coronary artery disease; TGCT cis rs28595532 0.920 rs115675321 chr4:119742153 A/T cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs7647973 1.000 rs7648995 chr3:49438803 C/T cg06212747 chr3:49208901 KLHDC8B -0.59 -4.72 -0.39 6.19e-6 Menarche (age at onset); TGCT cis rs10984561 0.881 rs10984553 chr9:122247521 G/A cg14242995 chr9:122249943 NA 0.75 6.41 0.5 2.7e-9 Pulmonary function decline; TGCT cis rs2964802 0.505 rs6872243 chr5:10818337 C/T cg14521931 chr5:10832172 NA -0.28 -4.73 -0.39 6.02e-6 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs13190036 1.000 rs6880798 chr5:176704457 C/T cg18465082 chr5:176734745 MXD3 -0.35 -4.64 -0.38 8.56e-6 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs55665837 0.559 rs11023209 chr11:14422600 T/C cg19336497 chr11:14380999 RRAS2 -0.33 -5.04 -0.41 1.57e-6 Vitamin D levels; TGCT cis rs116095464 0.558 rs7736600 chr5:231337 A/C cg22857025 chr5:266934 NA -0.33 -6.6 -0.51 1.1e-9 Breast cancer; TGCT cis rs6918586 0.615 rs198841 chr6:26111671 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.07e-9 Schizophrenia; TGCT cis rs6121246 0.567 rs6060262 chr20:30193071 A/C cg13852791 chr20:30311386 BCL2L1 0.69 4.65 0.39 8.44e-6 Mean corpuscular hemoglobin; TGCT cis rs939658 0.776 rs11631411 chr15:79445816 C/T cg17916960 chr15:79447300 NA -0.49 -7.57 -0.56 7.2e-12 Refractive error; TGCT cis rs709400 0.965 rs861534 chr14:104168701 C/T cg26031613 chr14:104095156 KLC1 1.12 16.24 0.82 1.71e-32 Body mass index; TGCT cis rs4319547 0.956 rs10773302 chr12:123043145 G/T cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.47 -0.44 2.42e-7 Body mass index; TGCT cis rs240764 0.658 rs12212435 chr6:101196080 T/C cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT cis rs9653442 0.527 rs11690905 chr2:100761473 C/T cg07810366 chr2:100720526 AFF3 0.36 5.31 0.43 4.89e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs380904 0.963 rs410836 chr8:144576849 A/G cg09317036 chr8:144635547 GSDMD 0.53 4.89 0.4 3.01e-6 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs9660180 0.967 rs10907191 chr1:1774820 A/T cg13866156 chr1:1669148 SLC35E2 -0.22 -5.22 -0.42 7.41e-7 Body mass index; TGCT cis rs6121246 0.567 rs6060399 chr20:30220823 C/T cg21427119 chr20:30132790 HM13 -0.43 -6.02 -0.48 1.86e-8 Mean corpuscular hemoglobin; TGCT cis rs3733585 0.699 rs28610447 chr4:9971517 T/C cg11266682 chr4:10021025 SLC2A9 -0.59 -7.85 -0.58 1.63e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7647973 1.000 rs62259947 chr3:49439924 T/C cg07636037 chr3:49044803 WDR6 -0.72 -5.72 -0.46 7.47e-8 Menarche (age at onset); TGCT cis rs7027203 0.828 rs4344139 chr9:96600298 T/C cg13679303 chr9:96623674 NA -0.66 -10.78 -0.7 1.64e-19 DNA methylation (variation); TGCT cis rs3138083 0.607 rs12376740 chr9:35639595 G/C cg07116010 chr9:35646325 NA 0.82 10.29 0.68 2.44e-18 Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel); TGCT cis rs36051895 0.659 rs62543863 chr9:5085417 C/T cg02405213 chr9:5042618 JAK2 -0.78 -9.94 -0.67 1.81e-17 Pediatric autoimmune diseases; TGCT cis rs7705042 0.647 rs10051379 chr5:141501662 T/G cg07392085 chr5:141489673 NDFIP1 -0.33 -4.5 -0.37 1.55e-5 Asthma; TGCT cis rs2235642 0.685 rs2667681 chr16:1653206 C/T cg08296037 chr16:1584118 IFT140;TMEM204 -0.28 -4.94 -0.41 2.44e-6 Coronary artery disease; TGCT cis rs904251 0.523 rs10807184 chr6:37483713 C/T cg25019722 chr6:37503610 NA -0.52 -7.86 -0.58 1.62e-12 Cognitive performance; TGCT cis rs9512730 0.527 rs11619722 chr13:27998600 T/C cg04070771 chr13:27998621 GTF3A 0.6 5.29 0.43 5.43e-7 Schizophrenia; TGCT trans rs561341 0.882 rs111484028 chr17:30287701 G/A cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs12908161 1.000 rs12910012 chr15:85298662 T/C cg11189052 chr15:85197271 WDR73 0.71 5.82 0.46 4.67e-8 Schizophrenia; TGCT cis rs4665809 0.941 rs1470096 chr2:26311482 T/C cg04944784 chr2:26401820 FAM59B -0.7 -6.49 -0.5 1.89e-9 Gut microbiome composition (summer); TGCT cis rs68170813 0.559 rs1121312 chr7:106927820 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs7618915 0.547 rs12487591 chr3:52642936 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.77 -0.39 5.03e-6 Bipolar disorder; TGCT cis rs7940866 0.903 rs11222421 chr11:130872351 A/T cg12179176 chr11:130786555 SNX19 0.56 5.25 0.43 6.27e-7 Schizophrenia; TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg17457637 chr7:27170717 HOXA4 -0.46 -5.11 -0.42 1.19e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs66573146 0.901 rs7668802 chr4:6986236 T/A cg05069807 chr4:6945702 TBC1D14 0.38 5.11 0.42 1.17e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs2032447 0.714 rs175319 chr6:25956172 A/G cg12310025 chr6:25882481 NA -0.72 -6.63 -0.51 9.27e-10 Intelligence (multi-trait analysis); TGCT cis rs4951018 0.821 rs11240547 chr1:205632932 A/G cg14893161 chr1:205819251 PM20D1 0.37 4.78 0.39 4.83e-6 Prostate-specific antigen levels; TGCT cis rs713587 0.776 rs3731623 chr2:25163783 T/C cg15423357 chr2:25149977 NA 0.59 5.98 0.47 2.17e-8 Body mass index in non-asthmatics; TGCT cis rs17433780 0.964 rs10493821 chr1:89475135 C/T cg09516651 chr1:89888402 LOC400759 0.31 5.56 0.45 1.59e-7 Carotid intima media thickness; TGCT cis rs501916 0.932 rs483656 chr15:48055932 T/C cg16110827 chr15:48056943 SEMA6D -0.17 -5.15 -0.42 9.73e-7 Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs2191566 0.821 rs62119173 chr19:44518073 G/A cg03039196 chr19:44506973 ZNF230 0.53 4.47 0.37 1.73e-5 Acute lymphoblastic leukemia (childhood); TGCT cis rs7666738 0.830 rs35531558 chr4:98938217 A/G cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs981844 0.712 rs4696507 chr4:154753702 G/A cg14289246 chr4:154710475 SFRP2 -0.98 -8.82 -0.62 8.67e-15 Response to statins (LDL cholesterol change); TGCT cis rs4665809 1.000 rs4665298 chr2:26256378 G/A cg22920501 chr2:26401640 FAM59B -0.71 -6.17 -0.48 9.06e-9 Gut microbiome composition (summer); TGCT cis rs7647973 0.710 rs6446284 chr3:49616997 A/G cg05785598 chr3:49045655 WDR6 0.41 4.66 0.39 8.03e-6 Menarche (age at onset); TGCT cis rs2239547 0.522 rs6445550 chr3:52983434 G/A cg10802521 chr3:52805072 NEK4 -0.64 -6.13 -0.48 1.06e-8 Schizophrenia; TGCT cis rs514406 0.861 rs7417821 chr1:53295117 A/G cg08736216 chr1:53307985 ZYG11A -0.25 -4.79 -0.4 4.59e-6 Monocyte count; TGCT cis rs2072499 0.966 rs2253677 chr1:156171296 C/G cg06970220 chr1:156163860 SLC25A44 -0.73 -6.46 -0.5 2.13e-9 Testicular germ cell tumor; TGCT cis rs7539409 0.651 rs6696140 chr1:84317468 C/T cg10977910 chr1:84465055 TTLL7 -0.88 -5.62 -0.45 1.19e-7 Alzheimer's disease; TGCT cis rs559406 0.540 rs888267 chr18:12773838 G/A cg23598886 chr18:12777645 NA 0.36 4.54 0.38 1.32e-5 Psoriasis; TGCT cis rs2204008 0.782 rs117824012 chr12:38215517 T/C cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs2243480 1.000 rs4718317 chr7:65648901 A/G cg18252515 chr7:66147081 NA 1.22 7.98 0.58 8.46e-13 Diabetic kidney disease; TGCT cis rs67311347 1.000 rs977652 chr3:40479169 A/G cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs1775715 0.870 rs3847415 chr10:32219456 G/T cg14930904 chr10:32216787 ARHGAP12 0.49 4.61 0.38 9.88e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs10504229 0.728 rs17215621 chr8:58152706 C/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs9611565 0.559 rs4822049 chr22:41993496 G/A cg03806693 chr22:41940476 POLR3H -1.11 -11.64 -0.72 1.26e-21 Vitiligo; TGCT cis rs4680 0.701 rs4646317 chr22:19952168 G/A cg23601416 chr22:19950040 COMT -0.38 -4.8 -0.4 4.47e-6 Blood metabolite levels; TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg25767906 chr1:53392781 SCP2 -0.51 -5.91 -0.47 3.09e-8 Monocyte count; TGCT cis rs5750830 0.649 rs5750815 chr22:39798449 T/C cg11247378 chr22:39784982 NA -0.73 -9.59 -0.65 1.22e-16 Intelligence (multi-trait analysis); TGCT cis rs2066819 1.000 rs2291361 chr12:56717805 G/A cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs6088580 0.634 rs6087580 chr20:32992592 A/G cg08999081 chr20:33150536 PIGU -0.28 -5.4 -0.44 3.26e-7 Glomerular filtration rate (creatinine); TGCT cis rs1218582 0.711 rs4845677 chr1:154838050 C/T cg16680214 chr1:154839983 KCNN3 -0.41 -8.75 -0.62 1.29e-14 Prostate cancer; TGCT cis rs12188164 1.000 rs12188678 chr5:428231 T/C cg17553881 chr5:443987 EXOC3;C5orf55 -0.41 -4.77 -0.39 5.03e-6 Cystic fibrosis severity; TGCT cis rs1552244 0.882 rs56125067 chr3:9984130 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.94 5.89 0.47 3.37e-8 Alzheimer's disease; TGCT cis rs17376456 0.877 rs10476598 chr5:93367281 C/T cg21475434 chr5:93447410 FAM172A -0.66 -5.04 -0.41 1.62e-6 Diabetic retinopathy; TGCT cis rs3008870 0.959 rs2985816 chr1:67387750 G/T cg03991309 chr1:68237761 GNG12 0.27 4.56 0.38 1.23e-5 Lymphocyte percentage of white cells; TGCT cis rs739496 0.579 rs12582302 chr12:112345634 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs1480597 0.518 rs10793552 chr10:45162388 G/A cg12063947 chr10:45878068 ALOX5 0.28 4.45 0.37 1.86e-5 Parkinson's disease; TGCT cis rs2295359 0.892 rs72676058 chr1:67627681 C/A cg12940439 chr1:67600707 NA 0.58 5.9 0.47 3.2e-8 Psoriasis; TGCT cis rs7666738 0.830 rs4619898 chr4:98959646 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs916888 0.821 rs199525 chr17:44847834 T/G cg01570182 chr17:44337453 NA 1.01 9.34 0.64 4.88e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10504229 0.683 rs72649192 chr8:58110490 T/C cg20607798 chr8:58055168 NA 0.62 5.21 0.42 7.64e-7 Developmental language disorder (linguistic errors); TGCT cis rs2839186 0.565 rs2839183 chr21:47687144 G/A cg12379764 chr21:47803548 PCNT 0.5 5.6 0.45 1.33e-7 Testicular germ cell tumor; TGCT cis rs7267979 1.000 rs761025 chr20:25426968 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9372498 0.536 rs62422235 chr6:118971913 G/A cg21191810 chr6:118973309 C6orf204 -0.38 -4.85 -0.4 3.6e-6 Diastolic blood pressure; TGCT cis rs10791097 0.690 rs12284540 chr11:130729772 T/C cg05962950 chr11:130786565 SNX19 0.81 9.71 0.66 6.35e-17 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4273100 0.646 rs6587216 chr17:19224397 G/C cg01534423 chr17:18965556 NA -0.79 -6.76 -0.52 4.91e-10 Schizophrenia; TGCT cis rs67311347 1.000 rs9875245 chr3:40442280 G/T cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs4665809 0.878 rs892448 chr2:26366205 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.29 -0.49 5.08e-9 Gut microbiome composition (summer); TGCT cis rs4819052 0.851 rs2838849 chr21:46671027 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12210905 0.688 rs78285097 chr6:27374644 G/C cg08851530 chr6:28072375 NA 1.33 5.85 0.47 4.08e-8 Hip circumference adjusted for BMI; TGCT trans rs916888 0.779 rs199498 chr17:44865603 A/G cg22968622 chr17:43663579 NA 0.96 7.81 0.57 2.08e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7208859 0.573 rs73267872 chr17:29067207 T/C cg14008862 chr17:28927542 LRRC37B2 0.76 4.52 0.38 1.42e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs6967414 0.786 rs6953825 chr7:6755624 A/C cg00387323 chr7:6746715 ZNF12 0.76 4.65 0.39 8.23e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs2242194 0.816 rs6671688 chr1:154994265 T/C cg24348479 chr1:155007323 DCST1;DCST2 0.27 5.67 0.45 9.51e-8 Schizophrenia; TGCT cis rs2688608 0.620 rs7080350 chr10:75577843 A/G cg23231163 chr10:75533350 FUT11 0.26 4.55 0.38 1.27e-5 Inflammatory bowel disease; TGCT cis rs12711979 0.509 rs13035992 chr2:3826597 G/A cg17052675 chr2:3827356 NA -0.55 -12.73 -0.75 2.94e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs4319547 0.626 rs10744210 chr12:122931793 A/G cg05707623 chr12:122985044 ZCCHC8 -0.71 -5.49 -0.44 2.16e-7 Body mass index; TGCT cis rs6088580 0.634 rs1205336 chr20:32926336 G/A cg06115741 chr20:33292138 TP53INP2 -0.53 -4.7 -0.39 6.67e-6 Glomerular filtration rate (creatinine); TGCT cis rs7091068 0.616 rs1890657 chr10:95506087 G/A cg20715218 chr10:95462985 C10orf4 0.52 4.62 0.38 9.33e-6 Urinary tract infection frequency; TGCT cis rs10504229 0.683 rs2088217 chr8:58113124 C/T cg08280861 chr8:58055591 NA 0.41 4.63 0.38 8.93e-6 Developmental language disorder (linguistic errors); TGCT cis rs67311347 0.577 rs11712626 chr3:40259927 G/A cg13683864 chr3:40499215 RPL14 -0.79 -7.4 -0.55 1.83e-11 Renal cell carcinoma; TGCT cis rs7565124 1.000 rs7565124 chr2:20261685 G/A cg00462460 chr2:20212509 MATN3 -0.43 -4.64 -0.38 8.69e-6 Major depressive disorder; TGCT cis rs7726839 0.578 rs10080150 chr5:593160 C/T cg09021430 chr5:549028 NA 0.39 7.6 0.56 6.25e-12 Obesity-related traits; TGCT cis rs2456568 0.548 rs7117597 chr11:93655091 A/G cg17595323 chr11:93583763 C11orf90 -0.43 -5.54 -0.45 1.7e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs11190604 0.767 rs11190534 chr10:102190930 G/A cg23241863 chr10:102295624 HIF1AN 0.62 4.79 0.4 4.69e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7296418 0.699 rs11608297 chr12:123826642 T/C cg00376283 chr12:123451042 ABCB9 0.63 5.42 0.44 3.02e-7 Platelet count; TGCT cis rs10504229 1.000 rs114312649 chr8:58182539 C/G cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs4285028 0.747 rs3732407 chr3:121416623 G/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.93 -7.31 -0.55 2.85e-11 Multiple sclerosis; TGCT cis rs9549260 0.564 rs4943805 chr13:41270080 A/G cg21288729 chr13:41239152 FOXO1 0.86 8.0 0.58 7.71e-13 Red blood cell count; TGCT cis rs13242816 1.000 rs56250718 chr7:116103303 A/G cg02799643 chr7:116139180 CAV2 -0.45 -5.38 -0.44 3.5e-7 P wave duration; TGCT cis rs2721195 1.000 rs11542372 chr8:145677089 G/A cg17328964 chr8:145687451 CYHR1 0.48 6.96 0.53 1.71e-10 Age at first birth; TGCT cis rs4699052 0.963 rs2061646 chr4:104183894 T/C cg16532752 chr4:104119610 CENPE -0.55 -4.97 -0.41 2.19e-6 Testicular germ cell tumor; TGCT cis rs9611519 0.894 rs8136923 chr22:41470522 G/A cg13695892 chr22:41940480 POLR3H -0.54 -4.78 -0.39 4.93e-6 Neuroticism; TGCT cis rs12477438 0.798 rs9679602 chr2:99577827 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.72 6.25 0.49 5.98e-9 Chronic sinus infection; TGCT cis rs9467773 0.967 rs6456732 chr6:26514445 T/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs4727027 0.866 rs3735311 chr7:148877737 T/C cg12479418 chr7:148823350 ZNF425;ZNF398 0.51 4.77 0.39 5.16e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs208520 0.526 rs9351542 chr6:66788571 A/G cg07460842 chr6:66804631 NA -1.08 -15.95 -0.82 8.03e-32 Exhaled nitric oxide output; TGCT cis rs155076 1.000 rs261432 chr13:21865915 G/C cg11317459 chr13:21872234 NA -1.3 -11.68 -0.72 1.02e-21 White matter hyperintensity burden; TGCT cis rs1799949 0.965 rs4793237 chr17:41436595 A/T cg19454999 chr17:41278357 BRCA1;NBR2 0.42 4.5 0.37 1.54e-5 Menopause (age at onset); TGCT cis rs7584330 0.697 rs9287620 chr2:238368730 C/T cg14458575 chr2:238380390 NA 0.56 8.88 0.62 6.43e-15 Prostate cancer; TGCT cis rs1799949 0.965 rs6503727 chr17:41312859 C/T cg10047753 chr17:41438598 NA 0.77 7.43 0.56 1.54e-11 Menopause (age at onset); TGCT trans rs7618501 0.665 rs7621352 chr3:50070763 A/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.88 -9.92 -0.67 1.95e-17 Intelligence (multi-trait analysis); TGCT cis rs548987 0.529 rs9467618 chr6:25824809 C/T cg03517284 chr6:25882590 NA -0.55 -4.44 -0.37 1.93e-5 Homocysteine levels; TGCT cis rs2295359 1.000 rs963427 chr1:67609347 A/G cg03340356 chr1:67600835 NA 0.37 4.63 0.38 9.1e-6 Psoriasis; TGCT cis rs7267979 1.000 rs2257809 chr20:25266476 C/T cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6448317 0.954 rs13139649 chr4:24922007 C/A cg21108841 chr4:24914750 CCDC149 -0.61 -4.63 -0.38 8.9e-6 Heschl's gyrus morphology; TGCT cis rs7703051 0.513 rs59014134 chr5:74589385 C/T cg00601450 chr5:74908170 NA 0.44 4.8 0.4 4.4e-6 LDL cholesterol;Age-related disease endophenotypes;Age-related diseases, mortality and associated endophenotypes; TGCT cis rs7552404 0.765 rs211717 chr1:76106969 G/A cg03433033 chr1:76189801 ACADM -0.84 -10.07 -0.67 8.46e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6121246 0.954 rs6058470 chr20:30416827 A/T cg13852791 chr20:30311386 BCL2L1 0.8 6.12 0.48 1.15e-8 Mean corpuscular hemoglobin; TGCT cis rs826838 1.000 rs10880963 chr12:38748408 T/C cg13010199 chr12:38710504 ALG10B 0.82 6.88 0.53 2.57e-10 Heart rate; TGCT cis rs1129187 0.702 rs2296805 chr6:42928758 T/G cg13397359 chr6:42928475 GNMT 0.58 4.8 0.4 4.39e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs950169 0.922 rs62028133 chr15:84919375 A/C cg11189052 chr15:85197271 WDR73 0.83 6.67 0.51 7.71e-10 Schizophrenia; TGCT cis rs6674176 0.542 rs3011225 chr1:44319373 G/A cg12908607 chr1:44402522 ARTN -0.63 -7.18 -0.54 5.58e-11 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs10504229 0.728 rs72650867 chr8:58154912 C/T cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs2255336 0.817 rs4764430 chr12:10517808 A/G cg16084090 chr12:10586130 KLRC2 0.3 4.59 0.38 1.06e-5 Blood protein levels; TGCT cis rs2579519 0.556 rs4907302 chr2:96217197 C/G cg23100626 chr2:96804247 ASTL 0.41 4.71 0.39 6.59e-6 Diastolic blood pressure; TGCT cis rs9611565 0.879 rs4820437 chr22:41761290 T/C cg02107564 chr22:41488750 EP300 -0.54 -4.44 -0.37 1.95e-5 Vitiligo; TGCT cis rs950027 0.620 rs1617984 chr15:45622662 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 6.06 0.48 1.48e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs12479064 0.505 rs62153764 chr2:99818612 T/G cg14399236 chr2:99771627 LIPT1;TSGA10 -0.84 -6.7 -0.52 6.49e-10 Chronic sinus infection; TGCT cis rs7226408 0.857 rs17652454 chr18:34476108 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs988712 0.705 rs1488830 chr11:27636885 A/G cg10635145 chr11:27742435 BDNF -0.36 -4.98 -0.41 2.1e-6 Obesity; TGCT cis rs910316 0.967 rs119076 chr14:75572419 G/T cg08847533 chr14:75593920 NEK9 -0.96 -10.44 -0.68 1.05e-18 Height; TGCT cis rs13217239 0.646 rs62401067 chr6:27018101 T/A cg26531700 chr6:26746687 NA 0.68 6.65 0.51 8.26e-10 Schizophrenia; TGCT cis rs2836974 0.605 rs2836988 chr21:40707975 A/G cg06238570 chr21:40685208 BRWD1 -0.82 -8.79 -0.62 1.03e-14 Cognitive function; TGCT cis rs4478858 0.735 rs7526095 chr1:31797581 C/T cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs56104184 0.723 rs73063515 chr19:49407715 C/T cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs4372836 0.543 rs6742291 chr2:29007349 T/C cg09522027 chr2:28974177 PPP1CB -0.77 -7.59 -0.56 6.62e-12 Body mass index; TGCT cis rs9807989 0.507 rs6743516 chr2:103036335 A/G cg03938978 chr2:103052716 IL18RAP 0.27 5.4 0.44 3.31e-7 Asthma; TGCT cis rs1949733 0.523 rs16842560 chr4:8544238 G/A cg13073564 chr4:8508604 NA 0.5 4.94 0.41 2.46e-6 Response to antineoplastic agents; TGCT cis rs7584330 0.554 rs3751111 chr2:238426953 G/T cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs1150668 0.768 rs1150716 chr6:28262698 T/G cg13525197 chr6:28411240 ZSCAN23 -0.49 -4.86 -0.4 3.52e-6 Pubertal anthropometrics; TGCT cis rs9399135 0.507 rs2072825 chr6:135253451 A/G cg24558204 chr6:135376177 HBS1L -0.47 -4.81 -0.4 4.35e-6 Red blood cell count; TGCT cis rs7617773 0.817 rs4131362 chr3:48329036 A/C cg11946769 chr3:48343235 NME6 0.74 6.34 0.49 3.97e-9 Coronary artery disease; TGCT cis rs10779751 0.734 rs1211575 chr1:11118390 G/A cg08854313 chr1:11322531 MTOR 0.84 8.3 0.6 1.47e-13 Body mass index; TGCT cis rs9914988 0.832 rs11650788 chr17:27174523 T/A cg20469991 chr17:27169893 C17orf63 -0.69 -4.6 -0.38 1.01e-5 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs8017423 0.647 rs4904677 chr14:90819245 C/T cg04374321 chr14:90722782 PSMC1 -0.58 -5.75 -0.46 6.5e-8 Mortality in heart failure; TGCT cis rs7552404 0.883 rs77773255 chr1:76217193 G/A cg03433033 chr1:76189801 ACADM 0.82 9.74 0.66 5.46e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7027203 1.000 rs7856374 chr9:96529791 G/A cg14598338 chr9:96623480 NA 0.58 8.5 0.61 5.15e-14 DNA methylation (variation); TGCT cis rs9296092 0.538 rs9461880 chr6:33518714 C/T cg13560919 chr6:33536144 NA -0.2 -4.63 -0.38 9.25e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs2075371 0.829 rs35897242 chr7:134004041 G/A cg11752832 chr7:134001865 SLC35B4 0.74 6.69 0.51 6.91e-10 Mean platelet volume; TGCT cis rs68170813 0.559 rs4730231 chr7:106942039 G/C cg02696742 chr7:106810147 HBP1 -0.69 -5.73 -0.46 7.17e-8 Coronary artery disease; TGCT cis rs644799 0.540 rs10831419 chr11:95478037 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.59 5.76 0.46 6.12e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT trans rs1814175 0.803 rs11040451 chr11:49650639 C/T cg03929089 chr4:120376271 NA -0.65 -7.44 -0.56 1.46e-11 Height; TGCT cis rs7617773 0.817 rs35456569 chr3:48250899 T/A cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs950169 1.000 rs12916348 chr15:84765527 C/T cg11189052 chr15:85197271 WDR73 0.69 5.91 0.47 3.07e-8 Schizophrenia; TGCT cis rs3829109 0.564 rs3812578 chr9:139299673 G/C cg13741927 chr9:139327495 INPP5E -0.24 -5.15 -0.42 9.81e-7 Peak insulin response;Acute insulin response; TGCT cis rs17376456 0.825 rs10057130 chr5:93282557 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs2013441 1.000 rs2703785 chr17:20152418 C/T cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs7666738 0.791 rs13128640 chr4:99003918 A/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg18538332 chr22:24372958 LOC391322 -1.0 -12.48 -0.75 1.21e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs13256369 0.774 rs11777719 chr8:8581038 A/G cg17143192 chr8:8559678 CLDN23 0.6 5.39 0.44 3.35e-7 Obesity-related traits; TGCT cis rs7772486 0.686 rs9485019 chr6:146046381 C/G cg23711669 chr6:146136114 FBXO30 -0.88 -9.77 -0.66 4.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7647973 0.621 rs3774800 chr3:49334768 A/G cg03060546 chr3:49711283 APEH -0.52 -4.86 -0.4 3.53e-6 Menarche (age at onset); TGCT cis rs28595532 0.920 rs114670456 chr4:119771202 A/G cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs12762955 0.561 rs6560863 chr10:1013535 C/A cg26597838 chr10:835615 NA -0.45 -6.15 -0.48 9.6e-9 Response to angiotensin II receptor blocker therapy; TGCT cis rs10489202 0.632 rs203781 chr1:167880518 A/C cg24449463 chr1:168025552 DCAF6 -0.55 -6.54 -0.51 1.43e-9 Schizophrenia; TGCT cis rs7119038 0.818 rs10892286 chr11:118642085 A/C cg19308663 chr11:118741387 NA 0.3 5.59 0.45 1.37e-7 Sjögren's syndrome; TGCT cis rs873946 0.648 rs12767126 chr10:134556992 C/T cg26818010 chr10:134567672 INPP5A -0.37 -5.02 -0.41 1.74e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs908922 0.676 rs2105117 chr1:152484129 G/A cg20991723 chr1:152506922 NA 0.47 6.55 0.51 1.4e-9 Hair morphology; TGCT cis rs1941023 0.584 rs950803 chr11:60152563 A/T cg08716584 chr11:60157161 MS4A7 0.29 4.6 0.38 1.05e-5 Congenital heart disease (maternal effect); TGCT cis rs748404 0.631 rs28702649 chr15:43648629 C/T cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.69 0.39 7.09e-6 Lung cancer; TGCT cis rs1878931 0.507 rs35214904 chr16:3410017 C/A cg26668626 chr16:3451006 ZNF174;ZNF434 -0.66 -5.18 -0.42 8.77e-7 Body mass index (adult); TGCT cis rs7010267 0.596 rs67819415 chr8:120016916 A/G cg17171407 chr8:119960777 TNFRSF11B 0.26 4.58 0.38 1.12e-5 Total body bone mineral density (age 45-60); TGCT cis rs11122272 0.735 rs2808591 chr1:231523421 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT trans rs7819412 0.740 rs11250119 chr8:11037034 C/T cg15556689 chr8:8085844 FLJ10661 -0.72 -6.74 -0.52 5.2e-10 Triglycerides; TGCT cis rs9814567 0.806 rs7626557 chr3:134318213 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2486288 0.656 rs7165039 chr15:45570413 C/G cg14582100 chr15:45693742 SPATA5L1 -0.43 -4.86 -0.4 3.48e-6 Glomerular filtration rate; TGCT cis rs9611565 0.503 rs5996062 chr22:42167464 C/G cg13695892 chr22:41940480 POLR3H 0.85 8.06 0.59 5.4e-13 Vitiligo; TGCT cis rs10875595 0.836 rs6868387 chr5:140660814 G/A cg24830062 chr5:140700576 TAF7 -0.6 -5.07 -0.41 1.42e-6 Pulmonary function decline; TGCT cis rs727505 0.721 rs55890146 chr7:124755461 A/T cg23710748 chr7:124431027 NA -0.26 -4.56 -0.38 1.2e-5 Lewy body disease; TGCT cis rs669446 0.561 rs639929 chr1:44083874 A/G cg12908607 chr1:44402522 ARTN -0.55 -5.9 -0.47 3.25e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs548181 0.668 rs579661 chr11:125474766 A/G cg03464685 chr11:125439445 EI24 1.43 10.1 0.67 7.31e-18 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT trans rs12599106 0.660 rs12919333 chr16:34991336 C/T cg07332563 chr6:291687 DUSP22 -0.74 -7.64 -0.57 5.21e-12 Menopause (age at onset); TGCT cis rs1552244 0.882 rs9757159 chr3:10039166 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs9467773 0.873 rs9295698 chr6:26566099 T/A cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs929354 0.713 rs7798816 chr7:156940574 A/G cg05182265 chr7:156933206 UBE3C -0.39 -8.98 -0.63 3.72e-15 Body mass index; TGCT cis rs1903068 0.785 rs28584303 chr4:55997622 C/T cg16572876 chr4:56024045 NA 0.44 4.94 0.41 2.47e-6 Endometriosis; TGCT cis rs295140 0.546 rs295134 chr2:201110223 A/G cg23649088 chr2:200775458 C2orf69 -0.32 -5.56 -0.45 1.55e-7 QT interval; TGCT cis rs9467773 0.620 rs1027203 chr6:26639332 G/C cg11502198 chr6:26597334 ABT1 0.51 4.61 0.38 9.7e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.505 rs416968 chr1:53183513 A/G cg24675658 chr1:53192096 ZYG11B -0.79 -9.7 -0.66 6.82e-17 Monocyte count; TGCT cis rs9611565 0.659 rs4822037 chr22:41945113 G/T cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs17401966 0.931 rs3748577 chr1:10357406 C/T cg19773385 chr1:10388646 KIF1B 0.21 4.65 0.39 8.25e-6 Hepatocellular carcinoma; TGCT cis rs7552404 0.731 rs11161836 chr1:76354333 C/T cg10523679 chr1:76189770 ACADM 0.83 7.47 0.56 1.28e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9311474 0.508 rs17052259 chr3:52593138 A/G cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.46e-9 Electroencephalogram traits; TGCT cis rs941408 1.000 rs1736184 chr19:2810248 G/A cg06609049 chr19:2785107 THOP1 0.81 7.55 0.56 8.21e-12 Total cholesterol levels; TGCT cis rs7772486 0.875 rs11755334 chr6:146399297 T/C cg23711669 chr6:146136114 FBXO30 0.89 9.47 0.65 2.36e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs2295359 0.892 rs2064689 chr1:67653010 G/A cg12940439 chr1:67600707 NA 0.6 6.28 0.49 5.25e-9 Psoriasis; TGCT cis rs6424115 1.000 rs7514394 chr1:24100223 A/G cg15997130 chr1:24165203 NA -0.9 -9.38 -0.64 4.07e-16 Immature fraction of reticulocytes; TGCT cis rs9486719 1.000 rs3798289 chr6:97023632 T/C cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs17001868 0.881 rs12484358 chr22:40774660 G/A cg07138101 chr22:40742427 ADSL 0.69 4.65 0.39 8.38e-6 Mammographic density (dense area); TGCT cis rs4906332 1.000 rs8004780 chr14:103853360 A/C cg26031613 chr14:104095156 KLC1 -0.52 -4.65 -0.39 8.37e-6 Coronary artery disease; TGCT cis rs1568889 0.877 rs34351528 chr11:28304293 T/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.85 8.8 0.62 9.82e-15 Bipolar disorder; TGCT cis rs2836974 0.644 rs2836982 chr21:40689171 C/A cg17971929 chr21:40555470 PSMG1 -0.65 -5.56 -0.45 1.56e-7 Cognitive function; TGCT cis rs394563 0.726 rs366905 chr6:149735097 T/A cg16235748 chr6:149772707 ZC3H12D -0.43 -4.89 -0.4 3.03e-6 Dupuytren's disease; TGCT cis rs950776 0.518 rs12902493 chr15:78819275 C/G cg06917634 chr15:78832804 PSMA4 0.95 9.52 0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs9430161 0.645 rs12081186 chr1:11034195 T/C cg27631724 chr1:11040367 C1orf127 0.53 6.05 0.48 1.58e-8 Ewing sarcoma; TGCT cis rs11690935 0.655 rs1028127 chr2:172530036 T/C cg13550731 chr2:172543902 DYNC1I2 0.71 6.19 0.49 8.01e-9 Schizophrenia; TGCT cis rs3733585 0.598 rs28677023 chr4:9958326 C/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7811142 0.830 rs6965458 chr7:99973402 G/A cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs78487399 0.731 rs72790940 chr2:43768545 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.64 4.48 0.37 1.66e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10744422 1.000 rs4993320 chr12:123338092 T/C cg25930673 chr12:123319894 HIP1R -0.86 -5.02 -0.41 1.72e-6 Schizophrenia; TGCT cis rs295140 0.526 rs295114 chr2:201195602 C/T cg23649088 chr2:200775458 C2orf69 0.29 4.93 0.4 2.63e-6 QT interval; TGCT cis rs2299587 0.554 rs2283106 chr8:17754330 G/A cg04898035 chr8:17640624 MTUS1 -0.21 -4.75 -0.39 5.54e-6 Economic and political preferences; TGCT cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.13 0.48 1.06e-8 Bipolar disorder; TGCT cis rs9517320 0.534 rs9556962 chr13:99156648 C/T cg20487152 chr13:99095054 FARP1 -0.24 -4.64 -0.38 8.83e-6 Longevity; TGCT cis rs13408808 0.679 rs6710727 chr2:168582788 A/G cg25427580 chr2:168675357 B3GALT1 0.39 4.46 0.37 1.82e-5 Obesity-related traits; TGCT cis rs10836699 0.772 rs11033996 chr11:37177868 A/G cg18520238 chr11:36422557 PRR5L 0.17 4.44 0.37 1.94e-5 Low high density lipoprotein cholesterol levels; TGCT cis rs524281 0.861 rs9736673 chr11:65924024 T/A cg00563793 chr11:65837595 PACS1 0.58 4.92 0.4 2.66e-6 Electroencephalogram traits; TGCT cis rs10489525 1.000 rs10489525 chr1:115263685 A/G cg12756093 chr1:115239321 AMPD1 0.35 4.53 0.38 1.38e-5 Autism; TGCT cis rs9527 0.615 rs11191489 chr10:104740568 C/A cg04362960 chr10:104952993 NT5C2 0.68 5.77 0.46 5.91e-8 Arsenic metabolism; TGCT trans rs916888 0.773 rs199448 chr17:44809001 A/G cg07870213 chr5:140052090 DND1 0.66 8.23 0.59 2.18e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8103278 0.740 rs2341097 chr19:46268902 C/T cg11657440 chr19:46296263 DMWD -0.55 -5.4 -0.44 3.25e-7 Coronary artery disease; TGCT cis rs1008375 1.000 rs4698651 chr4:17694223 A/G cg18681998 chr4:17616180 MED28 0.78 7.27 0.55 3.58e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3772130 1.000 rs13083794 chr3:121464928 T/G cg01951420 chr3:121553821 IQCB1;EAF2 0.54 4.85 0.4 3.66e-6 Cognitive performance; TGCT cis rs2299587 0.689 rs6586670 chr8:17772332 A/G cg01800426 chr8:17659068 MTUS1 -0.69 -6.01 -0.47 1.96e-8 Economic and political preferences; TGCT cis rs9894429 0.789 rs9747336 chr17:79584189 C/T cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.03e-17 Eye color traits; TGCT cis rs2255336 0.608 rs7958658 chr12:10518828 C/G cg16084090 chr12:10586130 KLRC2 0.3 4.62 0.38 9.55e-6 Blood protein levels; TGCT cis rs13217239 0.646 rs2142685 chr6:27054497 C/T cg06035815 chr6:26189597 HIST1H4D 0.44 4.53 0.38 1.39e-5 Schizophrenia; TGCT cis rs58688157 0.883 rs7936397 chr11:577534 G/A cg16486109 chr11:613632 IRF7 0.34 5.0 0.41 1.87e-6 Systemic lupus erythematosus; TGCT cis rs17665859 1.000 rs17665859 chr8:445601 T/C cg17960703 chr8:356704 FBXO25 1.48 5.62 0.45 1.22e-7 Bilirubin levels; TGCT cis rs137699 0.652 rs137706 chr22:39751400 T/G cg11247378 chr22:39784982 NA -0.6 -5.94 -0.47 2.68e-8 IgG glycosylation; TGCT cis rs775227 0.574 rs16861158 chr3:113261709 G/T cg18753928 chr3:113234510 CCDC52 -0.66 -4.49 -0.37 1.64e-5 Dental caries; TGCT cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg11890956 chr21:40555474 PSMG1 -0.75 -7.28 -0.55 3.44e-11 Cognitive function; TGCT cis rs9916302 0.706 rs11655972 chr17:37407072 C/T cg07936489 chr17:37558343 FBXL20 -0.82 -6.2 -0.49 7.86e-9 Glomerular filtration rate (creatinine); TGCT cis rs3858526 0.920 rs11039698 chr11:5950907 C/T cg05234568 chr11:5960015 NA -0.48 -4.77 -0.39 5.08e-6 DNA methylation (variation); TGCT cis rs2463822 0.925 rs12292586 chr11:62156312 C/T cg06239285 chr11:62104954 ASRGL1 -0.94 -6.61 -0.51 1.03e-9 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs10256972 0.621 rs2363285 chr7:1091644 C/T cg16145915 chr7:1198662 ZFAND2A -0.39 -4.57 -0.38 1.17e-5 Longevity;Endometriosis; TGCT cis rs9611565 0.649 rs139553 chr22:42187199 A/G cg17554472 chr22:41940697 POLR3H 0.45 4.66 0.39 8.18e-6 Vitiligo; TGCT cis rs9368481 0.554 rs2754603 chr6:26965139 T/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.36 -4.58 -0.38 1.11e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9325144 0.505 rs7955162 chr12:38711658 G/A cg26384229 chr12:38710491 ALG10B 0.97 8.97 0.63 3.86e-15 Morning vs. evening chronotype; TGCT cis rs1218582 0.774 rs11264284 chr1:154875793 C/T cg16680214 chr1:154839983 KCNN3 -0.42 -9.25 -0.64 8.37e-16 Prostate cancer; TGCT cis rs1215050 0.791 rs783960 chr4:98893437 A/G cg05340658 chr4:99064831 C4orf37 -0.46 -5.82 -0.46 4.74e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9733 0.596 rs1136808 chr1:150702717 G/C cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs478304 0.651 rs7110576 chr11:65512057 T/G cg27068330 chr11:65405492 SIPA1 -0.93 -9.34 -0.64 4.92e-16 Acne (severe); TGCT cis rs2692947 0.696 rs2969490 chr2:96803904 A/G cg23100626 chr2:96804247 ASTL 0.41 5.03 0.41 1.65e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs79149102 0.579 rs7174129 chr15:75305040 A/G cg09165964 chr15:75287851 SCAMP5 -1.04 -5.71 -0.46 7.93e-8 Lung cancer; TGCT trans rs1864729 0.748 rs2583509 chr8:98294151 G/A cg08679828 chr8:102218111 ZNF706 -1.03 -6.71 -0.52 6.09e-10 Estradiol plasma levels (breast cancer); TGCT cis rs6089584 0.850 rs881993 chr20:60623862 A/G cg16423285 chr20:60520624 NA -0.69 -7.11 -0.54 8.23e-11 Body mass index; TGCT cis rs1348850 0.598 rs1405717 chr2:178500101 G/T cg22681709 chr2:178499509 PDE11A -0.52 -6.65 -0.51 8.49e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs6964587 0.967 rs6465340 chr7:91588664 G/A cg22709100 chr7:91322751 NA 0.28 4.54 0.38 1.3e-5 Breast cancer; TGCT cis rs832540 0.931 rs33319 chr5:56206675 C/A cg24531977 chr5:56204891 C5orf35 -0.53 -5.49 -0.44 2.15e-7 Coronary artery disease; TGCT cis rs12497850 0.931 rs4974082 chr3:48999323 G/A cg07636037 chr3:49044803 WDR6 0.96 10.42 0.68 1.17e-18 Parkinson's disease; TGCT cis rs1218582 0.710 rs9794000 chr1:154878876 T/A cg03351412 chr1:154909251 PMVK 0.54 5.02 0.41 1.72e-6 Prostate cancer; TGCT cis rs7020830 0.571 rs3780335 chr9:37376587 A/G cg14235030 chr9:37121269 ZCCHC7 -0.44 -4.78 -0.39 4.87e-6 Schizophrenia; TGCT trans rs208520 1.000 rs12193077 chr6:66989548 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs9400467 0.537 rs12192695 chr6:111453046 C/T cg15721981 chr6:111408429 SLC16A10 0.72 4.6 0.38 1.01e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs1403694 0.515 rs1624569 chr3:186450069 A/G cg12454167 chr3:186435060 KNG1 0.45 7.22 0.54 4.67e-11 Blood protein levels; TGCT cis rs3125734 0.633 rs7100297 chr10:63985100 T/C cg05499367 chr10:63213510 TMEM26 -0.33 -4.52 -0.38 1.4e-5 Rheumatoid arthritis; TGCT cis rs6964587 0.692 rs2027950 chr7:91863700 C/G cg17063962 chr7:91808500 NA -0.73 -6.75 -0.52 5.17e-10 Breast cancer; TGCT cis rs7267979 1.000 rs34645895 chr20:25368373 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs1005277 0.579 rs1740732 chr10:38491385 C/T cg27523141 chr10:43048294 ZNF37B 0.71 8.14 0.59 3.46e-13 Extrinsic epigenetic age acceleration; TGCT cis rs4372836 0.553 rs6706858 chr2:28992607 C/G cg09522027 chr2:28974177 PPP1CB -0.73 -7.07 -0.54 9.78e-11 Body mass index; TGCT cis rs7953249 0.722 rs2255531 chr12:121414915 G/A cg02403541 chr12:121454288 C12orf43 0.6 5.1 0.42 1.23e-6 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs12681287 0.640 rs7017706 chr8:87480890 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.41 -0.5 2.8e-9 Caudate activity during reward; TGCT cis rs1153858 1.000 rs4627277 chr15:45652768 C/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7208859 0.673 rs73277967 chr17:29184166 T/A cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11105298 0.891 rs10858854 chr12:89835728 C/A cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4819052 0.851 rs2838849 chr21:46671027 A/G cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2346177 0.816 rs74179078 chr2:46654651 T/A cg26688816 chr2:46740690 ATP6V1E2 -0.46 -5.18 -0.42 8.6e-7 HDL cholesterol; TGCT cis rs9811920 0.809 rs4928153 chr3:99808445 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.43 4.77 0.39 5.16e-6 Axial length; TGCT cis rs7959452 0.535 rs11615712 chr12:69619736 A/T cg20891283 chr12:69753455 YEATS4 -0.59 -5.55 -0.45 1.68e-7 Blood protein levels; TGCT cis rs72781680 0.752 rs72780185 chr2:24003967 G/A cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs62244186 0.748 rs4682987 chr3:44674996 C/T cg04389838 chr3:44770851 ZNF501 -0.38 -5.02 -0.41 1.75e-6 Depressive symptoms; TGCT cis rs8078723 1.000 rs2227336 chr17:38174855 T/G cg17467752 chr17:38218738 THRA 0.52 4.93 0.41 2.54e-6 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs9400467 0.537 rs56272203 chr6:111492436 C/A cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs709400 0.628 rs7155014 chr14:103863970 C/G cg26031613 chr14:104095156 KLC1 0.81 8.8 0.62 1.01e-14 Body mass index; TGCT cis rs600231 0.542 rs11227196 chr11:65234922 G/A cg17120908 chr11:65337727 SSSCA1 -0.56 -4.45 -0.37 1.86e-5 Bone mineral density; TGCT cis rs877426 0.634 rs7329801 chr13:114824560 G/A cg16820615 chr13:114884918 RASA3 0.32 5.1 0.42 1.21e-6 Facial morphology (factor 14, intercanthal width); TGCT cis rs10256972 0.758 rs11980081 chr7:1069372 T/C cg03188948 chr7:1209495 NA 0.45 5.85 0.47 4.04e-8 Longevity;Endometriosis; TGCT cis rs6912958 0.702 rs2300909 chr6:88212100 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.06 -0.41 1.45e-6 Monocyte percentage of white cells; TGCT cis rs2439831 0.867 rs7170489 chr15:43636651 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs3820068 0.581 rs72645871 chr1:15926142 G/A cg05660106 chr1:15850417 CASP9 0.82 8.02 0.58 6.63e-13 Systolic blood pressure; TGCT cis rs57221529 0.766 rs17563576 chr5:560476 A/G cg09021430 chr5:549028 NA -0.43 -5.66 -0.45 1.01e-7 Lung disease severity in cystic fibrosis; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg16325326 chr1:53192061 ZYG11B -0.58 -6.63 -0.51 9.32e-10 Monocyte count; TGCT cis rs6951245 0.872 rs77434655 chr7:1098405 G/A cg03188948 chr7:1209495 NA 0.68 5.8 0.46 5.09e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT trans rs1005277 0.579 rs2472175 chr10:38382901 T/G cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.13e-14 Extrinsic epigenetic age acceleration; TGCT cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg08439880 chr3:133502540 NA -0.27 -4.82 -0.4 4.05e-6 Iron status biomarkers; TGCT cis rs12497850 0.931 rs6442130 chr3:48778027 A/G cg07636037 chr3:49044803 WDR6 0.93 10.07 0.67 8.61e-18 Parkinson's disease; TGCT cis rs9894429 0.738 rs8077038 chr17:79577127 T/G cg21028142 chr17:79581711 NPLOC4 -0.3 -7.03 -0.53 1.2e-10 Eye color traits; TGCT cis rs7954584 0.616 rs10743185 chr12:122356435 G/A cg21171335 chr12:122356390 WDR66 0.59 6.19 0.49 8.15e-9 Mean corpuscular volume; TGCT cis rs7647973 0.580 rs2117938 chr3:49263850 A/G cg06212747 chr3:49208901 KLHDC8B -0.65 -6.23 -0.49 6.72e-9 Menarche (age at onset); TGCT cis rs2467099 0.504 rs55956362 chr17:73901294 G/T cg10108402 chr17:73901394 MRPL38 -0.47 -4.47 -0.37 1.75e-5 Systolic blood pressure; TGCT cis rs28595532 0.920 rs116821181 chr4:119734892 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs2458413 0.543 rs2514658 chr8:105337871 G/A cg04554929 chr8:105342491 NA -0.61 -9.81 -0.66 3.55e-17 Paget's disease; TGCT cis rs17401966 0.838 rs61775887 chr1:10284733 T/C cg19773385 chr1:10388646 KIF1B -0.22 -4.6 -0.38 1.02e-5 Hepatocellular carcinoma; TGCT cis rs6570726 0.818 rs952405 chr6:145925952 T/C cg23711669 chr6:146136114 FBXO30 0.83 8.64 0.61 2.4e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs4509693 0.943 rs10732789 chr10:102496184 T/C cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs17197710 0.673 rs12576690 chr11:47321509 T/C cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7010267 0.935 rs7463176 chr8:119957625 A/G cg17171407 chr8:119960777 TNFRSF11B 0.33 6.18 0.49 8.29e-9 Total body bone mineral density (age 45-60); TGCT cis rs1552244 1.000 rs7628448 chr3:10146828 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.9 5.8 0.46 5.19e-8 Alzheimer's disease; TGCT cis rs17253792 0.822 rs10129890 chr14:56040413 A/T cg01858014 chr14:56050164 KTN1 -0.36 -4.55 -0.38 1.24e-5 Putamen volume; TGCT cis rs7811142 0.943 rs111757992 chr7:100016354 A/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg08280861 chr8:58055591 NA 0.36 4.91 0.4 2.77e-6 Developmental language disorder (linguistic errors); TGCT cis rs12510870 0.599 rs10019146 chr4:74453656 G/A cg05868023 chr4:75230803 EREG -0.55 -4.74 -0.39 5.71e-6 Iris color (b* coordinate); TGCT cis rs6121246 0.559 rs6058465 chr20:30397691 G/A cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs4319547 1.000 rs4319547 chr12:123079035 A/G cg23029597 chr12:123009494 RSRC2 -0.31 -5.01 -0.41 1.82e-6 Body mass index; TGCT cis rs116095464 0.558 rs62347677 chr5:227453 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.49 0.37 1.62e-5 Breast cancer; TGCT cis rs3796352 1.000 rs34933390 chr3:53006265 T/G cg15956490 chr3:53032818 SFMBT1 0.61 6.76 0.52 4.92e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs13256369 0.901 rs4841015 chr8:8567140 C/G cg06671706 chr8:8559999 CLDN23 0.34 4.59 0.38 1.09e-5 Obesity-related traits; TGCT cis rs7267979 0.932 rs424487 chr20:25468131 C/G cg16686733 chr20:25566563 NINL 0.56 5.69 0.46 8.49e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs797680 0.789 rs797671 chr1:93700363 C/A cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7618915 0.571 rs34115864 chr3:52612178 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.5 -4.81 -0.4 4.26e-6 Bipolar disorder; TGCT cis rs9926296 0.585 rs6500441 chr16:89828669 C/G cg04287289 chr16:89883240 FANCA 0.95 11.94 0.73 2.39e-22 Vitiligo; TGCT cis rs367943 1.000 rs348946 chr5:112822814 C/T cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs9733 0.650 rs9803935 chr1:150552622 T/G cg13175981 chr1:150552382 MCL1 0.52 5.75 0.46 6.55e-8 Tonsillectomy; TGCT cis rs4975616 0.804 rs457130 chr5:1336178 A/T cg07493874 chr5:1342172 CLPTM1L -0.27 -6.53 -0.51 1.55e-9 Lung cancer; TGCT cis rs72843506 0.722 rs117096120 chr17:20167693 G/A cg18979559 chr17:20280153 CCDC144C -0.64 -4.82 -0.4 4.04e-6 Schizophrenia; TGCT cis rs6912958 0.703 rs12207825 chr6:88098292 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.4 5.18 0.42 8.73e-7 Monocyte percentage of white cells; TGCT cis rs6545883 0.965 rs766447 chr2:61735569 C/T cg15711740 chr2:61764176 XPO1 -0.56 -5.1 -0.42 1.22e-6 Tuberculosis; TGCT cis rs9549260 0.753 rs9532562 chr13:41153585 A/G cg21288729 chr13:41239152 FOXO1 0.67 4.89 0.4 3e-6 Red blood cell count; TGCT cis rs3749237 0.595 rs11130192 chr3:49467206 C/G cg02487422 chr3:49467188 NICN1 0.61 6.29 0.49 5.08e-9 Resting heart rate; TGCT cis rs9560113 0.959 rs9555803 chr13:112179560 G/T cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs2730245 0.550 rs10258339 chr7:158670243 T/C cg11984989 chr7:158649758 WDR60 1.01 8.98 0.63 3.58e-15 Height; TGCT cis rs4383453 0.539 rs12636451 chr3:123102924 A/C cg04890266 chr3:123102914 ADCY5 -0.49 -7.91 -0.58 1.23e-12 Gestational age at birth (maternal effect); TGCT cis rs459571 0.876 rs2520095 chr9:136919568 A/G cg13789015 chr9:136890014 NCRNA00094 0.39 6.83 0.52 3.45e-10 Platelet distribution width; TGCT cis rs28386778 0.897 rs2727320 chr17:61865325 T/C cg11494091 chr17:61959527 GH2 0.61 14.34 0.79 4.3e-28 Prudent dietary pattern; TGCT cis rs9303401 0.659 rs12940212 chr17:56674474 T/C cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs3849570 0.961 rs7620240 chr3:81762787 G/T cg07356753 chr3:81810745 GBE1 -0.85 -8.16 -0.59 3.13e-13 Waist circumference;Body mass index; TGCT cis rs10504229 1.000 rs72650885 chr8:58175131 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs74544699 0.826 rs74499711 chr4:74842764 G/A cg16072462 chr4:74847758 PF4 0.78 5.16 0.42 9.32e-7 Growth-regulated protein alpha levels; TGCT cis rs2075165 0.935 rs933489 chr1:156235120 T/C cg20302342 chr1:156215951 PAQR6 0.39 5.67 0.45 9.49e-8 Tonsillectomy; TGCT cis rs7833790 0.724 rs4739627 chr8:82734657 A/G cg27398817 chr8:82754497 SNX16 -0.67 -5.34 -0.43 4.27e-7 Diastolic blood pressure; TGCT cis rs1580019 0.587 rs6972365 chr7:32548931 T/A cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.15 0.79 1.17e-27 Cognitive ability; TGCT cis rs9486715 0.867 rs926277 chr6:96868837 T/A cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs593982 0.920 rs563427 chr11:65484569 A/G cg08755490 chr11:65554678 OVOL1 1.35 8.23 0.59 2.2e-13 Atopic dermatitis; TGCT cis rs12681288 0.823 rs2701908 chr8:1003250 T/C cg04851639 chr8:1020857 NA -0.32 -5.39 -0.44 3.35e-7 Schizophrenia; TGCT cis rs453301 0.686 rs7017868 chr8:8873293 G/A cg00184457 chr8:8946301 NA -0.27 -4.92 -0.4 2.72e-6 Joint mobility (Beighton score); TGCT cis rs3806843 0.576 rs246030 chr5:140333154 C/G cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs7666738 0.830 rs1593573 chr4:98925293 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs2469997 1.000 rs2447181 chr8:120354288 T/A cg01792902 chr3:178864926 PIK3CA 0.78 6.66 0.51 7.93e-10 Hypertension (SNP x SNP interaction); TGCT cis rs9883204 0.855 rs11720108 chr3:123069058 C/T cg04890266 chr3:123102914 ADCY5 0.37 4.99 0.41 1.98e-6 Birth weight; TGCT cis rs62193398 1.000 rs62193398 chr2:202531264 T/C cg12618251 chr2:202899058 FZD7 0.53 4.47 0.37 1.75e-5 Breast cancer; TGCT cis rs295140 0.934 rs74853338 chr2:201171651 C/T cg04283868 chr2:201171347 SPATS2L 0.63 6.43 0.5 2.46e-9 QT interval; TGCT cis rs651907 0.535 rs2290859 chr3:101525625 C/T cg11279151 chr3:101281821 RG9MTD1 -0.32 -6.67 -0.51 7.53e-10 Colorectal cancer; TGCT cis rs2204008 0.754 rs11181244 chr12:38302454 T/C cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.31e-5 Bladder cancer; TGCT cis rs1218582 0.710 rs9793588 chr1:154878878 C/G cg24250549 chr1:154909240 PMVK 0.65 6.49 0.5 1.84e-9 Prostate cancer; TGCT cis rs950169 0.920 rs2135551 chr15:84707851 A/G cg17173187 chr15:85201210 NMB 0.47 5.22 0.42 7.36e-7 Schizophrenia; TGCT cis rs637571 0.522 rs1786175 chr11:65754808 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.67 6.69 0.51 6.95e-10 Eosinophil percentage of white cells; TGCT cis rs6088590 0.931 rs12625149 chr20:33425812 A/C cg24642439 chr20:33292090 TP53INP2 -0.68 -5.88 -0.47 3.55e-8 Coronary artery disease; TGCT trans rs7618501 1.000 rs2234391 chr3:49842625 A/G cg21659725 chr3:3221576 CRBN 0.98 15.33 0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs9329221 0.509 rs3088186 chr8:10226355 C/T cg21293242 chr8:11204541 TDH 0.43 4.45 0.37 1.88e-5 Neuroticism; TGCT cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs117785887 0.536 rs10457790 chr6:146359865 A/G cg06708562 chr6:146285465 SHPRH -0.8 -4.81 -0.4 4.23e-6 Interleukin-17 levels; TGCT cis rs13040088 0.935 rs62200158 chr20:61557906 C/T cg23096297 chr20:61557774 DIDO1 1.17 9.71 0.66 6.25e-17 Menopause (age at onset); TGCT cis rs3749237 0.595 rs885592 chr3:49497883 T/G cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs910316 1.000 rs175436 chr14:75608683 C/G cg23033748 chr14:75592666 NEK9 -0.3 -4.96 -0.41 2.26e-6 Height; TGCT cis rs4820539 0.966 rs5759600 chr22:23483769 C/A cg14186256 chr22:23484241 RTDR1 1.04 13.85 0.78 6.06e-27 Bone mineral density; TGCT cis rs6752107 0.846 rs7559194 chr2:234206799 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.22 4.69 0.39 7.05e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs614226 1.000 rs616157 chr12:120925795 T/C cg10072921 chr12:121022843 NA 0.45 4.86 0.4 3.45e-6 Type 1 diabetes nephropathy; TGCT cis rs2282802 0.685 rs2337081 chr5:139642414 A/C cg01081189 chr5:139537190 NA 0.29 5.24 0.43 6.57e-7 Intelligence (multi-trait analysis); TGCT cis rs12497850 0.864 rs6779394 chr3:49157771 G/A cg16497277 chr3:49208875 KLHDC8B -0.5 -4.56 -0.38 1.21e-5 Parkinson's disease; TGCT cis rs4663866 1.000 rs4663868 chr2:239161091 C/T cg17283117 chr2:239148619 HES6 0.98 4.52 0.38 1.42e-5 Irritable bowel syndrome; TGCT cis rs5769765 1.000 rs5770741 chr22:50270215 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs10986311 0.775 rs1007185 chr9:127136644 G/C cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.8 -0.4 4.45e-6 Vitiligo; TGCT cis rs9911578 0.967 rs7503190 chr17:57184162 A/C cg12560992 chr17:57184187 TRIM37 0.79 9.71 0.66 6.56e-17 Intelligence (multi-trait analysis); TGCT cis rs6964587 1.000 rs28927678 chr7:91715662 C/T cg17063962 chr7:91808500 NA 0.86 9.36 0.64 4.58e-16 Breast cancer; TGCT cis rs12971120 0.838 rs3794950 chr18:72182965 G/A cg26446133 chr18:72167187 CNDP2 -0.35 -5.84 -0.46 4.22e-8 Refractive error; TGCT cis rs5769765 0.913 rs28670284 chr22:50221973 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.19 -11.95 -0.73 2.3e-22 Schizophrenia; TGCT cis rs858239 0.601 rs12539331 chr7:23151330 A/G cg05602783 chr7:23145260 KLHL7 -0.71 -6.14 -0.48 1.03e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs2089162 1 rs2089162 chr15:78739763 A/G cg18825076 chr15:78729989 IREB2 -0.35 -5.31 -0.43 4.99e-7 Post bronchodilator FEV1/FVC ratio in COPD;Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs2153535 0.580 rs2327056 chr6:8443305 C/T cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs68170813 0.652 rs79295036 chr7:107193669 C/A cg02696742 chr7:106810147 HBP1 -0.59 -4.71 -0.39 6.61e-6 Coronary artery disease; TGCT cis rs7474896 0.616 rs2505239 chr10:38440765 A/G cg25427524 chr10:38739819 LOC399744 -0.35 -4.55 -0.38 1.24e-5 Obesity (extreme); TGCT cis rs6860806 0.531 rs270607 chr5:131649186 A/G cg24060327 chr5:131705240 SLC22A5 -0.72 -7.76 -0.57 2.7e-12 Breast cancer; TGCT cis rs478304 0.651 rs11227279 chr11:65495211 G/A cg27068330 chr11:65405492 SIPA1 -0.94 -9.51 -0.65 1.94e-16 Acne (severe); TGCT cis rs7017914 0.967 rs7825446 chr8:71664174 G/A cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs6918586 0.594 rs198842 chr6:26111448 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.07e-9 Schizophrenia; TGCT cis rs9291683 0.632 rs13137074 chr4:10042842 C/T cg00071950 chr4:10020882 SLC2A9 0.68 8.74 0.62 1.38e-14 Bone mineral density; TGCT cis rs986417 0.818 rs10148116 chr14:61101089 C/T cg27398547 chr14:60952738 C14orf39 1.57 10.0 0.67 1.28e-17 Gut microbiota (bacterial taxa); TGCT cis rs7552404 0.727 rs5745390 chr1:76306591 A/C cg10523679 chr1:76189770 ACADM 0.74 7.08 0.54 9.41e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs67073037 0.955 rs12620680 chr2:29144611 C/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs2688608 0.592 rs7923045 chr10:75487498 A/T cg15838173 chr10:75533400 FUT11 -0.3 -4.91 -0.4 2.78e-6 Inflammatory bowel disease; TGCT cis rs2721195 0.845 rs2721150 chr8:145724973 C/G cg17328964 chr8:145687451 CYHR1 -0.38 -5.07 -0.41 1.39e-6 Age at first birth; TGCT cis rs4820539 1.000 rs4822357 chr22:23473231 A/G cg14186256 chr22:23484241 RTDR1 0.92 8.41 0.6 8.13e-14 Bone mineral density; TGCT cis rs1215050 0.791 rs783959 chr4:98893476 C/T cg05340658 chr4:99064831 C4orf37 -0.47 -5.89 -0.47 3.41e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs860295 0.502 rs2886070 chr1:155973971 G/A cg05700447 chr1:155978627 NA -0.19 -4.57 -0.38 1.18e-5 Body mass index; TGCT cis rs7772486 0.719 rs2206141 chr6:146086192 A/G cg13319975 chr6:146136371 FBXO30 0.58 5.29 0.43 5.27e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs12136530 0.774 rs12140338 chr1:19766430 C/G cg18923740 chr1:19971790 NBL1 0.35 4.47 0.37 1.72e-5 Lead levels in blood; TGCT cis rs6121246 0.609 rs6088997 chr20:30289824 A/G cg18721089 chr20:30220636 NA 0.37 4.58 0.38 1.11e-5 Mean corpuscular hemoglobin; TGCT cis rs12049351 0.719 rs4925493 chr1:229623137 T/C cg12130225 chr1:229698885 NA 0.39 4.5 0.37 1.52e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs6912958 0.781 rs2273129 chr6:88182439 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.53 -4.85 -0.4 3.69e-6 Monocyte percentage of white cells; TGCT cis rs9399135 0.967 rs2327578 chr6:135329969 C/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs17376456 0.877 rs12109629 chr5:93359702 A/G cg25358565 chr5:93447407 FAM172A 0.92 8.4 0.6 8.88e-14 Diabetic retinopathy; TGCT cis rs514406 0.825 rs1242328 chr1:53396869 A/G cg25767906 chr1:53392781 SCP2 -0.51 -6.22 -0.49 6.83e-9 Monocyte count; TGCT cis rs7843479 0.526 rs34802507 chr8:21773853 C/T cg17168535 chr8:21777572 XPO7 0.78 7.35 0.55 2.29e-11 Mean corpuscular volume; TGCT cis rs1371867 0.817 rs1788179 chr8:101333345 A/G cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs4253772 0.550 rs9615913 chr22:46668515 A/T cg09491104 chr22:46646882 C22orf40 0.67 6.71 0.52 6.33e-10 LDL cholesterol;Cholesterol, total; TGCT cis rs8017423 0.647 rs4904673 chr14:90817338 G/A cg04374321 chr14:90722782 PSMC1 -0.58 -5.73 -0.46 7.04e-8 Mortality in heart failure; TGCT trans rs66573146 0.831 rs56081162 chr4:6989718 C/T cg07817883 chr1:32538562 TMEM39B 1.3 6.83 0.52 3.41e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs586688 1.000 rs647130 chr1:201637982 A/G cg22851694 chr1:202075546 NA 0.37 4.46 0.37 1.83e-5 Obesity-related traits; TGCT cis rs28374715 0.662 rs113913466 chr15:41483100 A/G cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.6 -0.72 1.65e-21 Ulcerative colitis; TGCT cis rs4788570 0.625 rs4788813 chr16:71625572 T/C cg06353428 chr16:71660113 MARVELD3 1.48 10.62 0.69 3.91e-19 Intelligence (multi-trait analysis); TGCT cis rs7191439 0.728 rs8056374 chr16:88790147 G/T cg27087555 chr16:88793112 FAM38A -0.48 -5.47 -0.44 2.41e-7 Plateletcrit; TGCT cis rs7267979 0.789 rs6083841 chr20:25384564 C/T cg03522245 chr20:25566470 NINL -0.52 -5.25 -0.43 6.43e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs28386778 0.897 rs1982400 chr17:61793818 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs7178572 0.568 rs1446312 chr15:77412189 G/C cg22256960 chr15:77711686 NA -0.86 -8.75 -0.62 1.27e-14 Type 2 diabetes; TGCT cis rs12908161 1.000 rs34900908 chr15:85257599 G/A cg17173187 chr15:85201210 NMB 0.59 6.77 0.52 4.55e-10 Schizophrenia; TGCT cis rs9972944 0.756 rs7222229 chr17:63765025 T/G cg07283582 chr17:63770753 CCDC46 -0.26 -5.3 -0.43 5.02e-7 Total body bone mineral density; TGCT cis rs10779751 0.734 rs1034528 chr1:11249132 G/C cg08854313 chr1:11322531 MTOR -0.82 -6.99 -0.53 1.5e-10 Body mass index; TGCT cis rs4631830 0.863 rs2249986 chr10:51521684 T/G cg10326726 chr10:51549505 MSMB -0.26 -5.35 -0.43 4.12e-7 Prostate-specific antigen levels; TGCT cis rs10131894 0.611 rs175000 chr14:75436367 T/C cg08847533 chr14:75593920 NEK9 -0.66 -6.29 -0.49 4.87e-9 Coronary artery disease; TGCT cis rs4713118 0.516 rs6931858 chr6:28078411 A/T cg12963246 chr6:28129442 ZNF389 0.51 4.87 0.4 3.3e-6 Parkinson's disease; TGCT cis rs4664308 0.740 rs877635 chr2:160902847 A/C cg03641300 chr2:160917029 PLA2R1 -0.26 -6.09 -0.48 1.3e-8 Idiopathic membranous nephropathy; TGCT cis rs6089584 1.000 rs3787425 chr20:60559256 C/T cg13770153 chr20:60521292 NA -0.44 -5.62 -0.45 1.21e-7 Body mass index; TGCT cis rs3749237 0.595 rs17650792 chr3:49390250 A/G cg03060546 chr3:49711283 APEH 0.76 8.57 0.61 3.4e-14 Resting heart rate; TGCT cis rs78487399 0.808 rs10169346 chr2:43741105 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.76 4.68 0.39 7.27e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs36405 1.000 rs36405 chr14:72357937 C/T cg10066683 chr14:71515513 PCNX -0.25 -4.7 -0.39 6.71e-6 Yang-deficiency constitution; TGCT cis rs10465746 0.780 rs11163862 chr1:84355418 A/T cg10977910 chr1:84465055 TTLL7 -0.64 -6.56 -0.51 1.29e-9 Obesity-related traits; TGCT cis rs9467773 0.620 rs3800303 chr6:26598188 A/G cg05738196 chr6:26577821 NA 0.88 11.09 0.71 2.86e-20 Intelligence (multi-trait analysis); TGCT cis rs7647973 1.000 rs62261249 chr3:49594060 T/C cg06212747 chr3:49208901 KLHDC8B -0.57 -4.59 -0.38 1.08e-5 Menarche (age at onset); TGCT cis rs10504229 0.728 rs72650858 chr8:58152832 G/A cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs7917772 0.560 rs10786697 chr10:104378563 G/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.56 5.45 0.44 2.6e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1552244 1.000 rs7615764 chr3:10082592 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs61931739 0.517 rs7958856 chr12:34294737 T/C cg06521331 chr12:34319734 NA -0.3 -4.55 -0.38 1.28e-5 Morning vs. evening chronotype; TGCT cis rs7267979 1.000 rs6050565 chr20:25347563 A/C cg03522245 chr20:25566470 NINL -0.62 -6.7 -0.52 6.66e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11191270 0.554 rs11191275 chr10:104142800 C/T cg15320455 chr10:103880129 LDB1 0.86 5.38 0.43 3.58e-7 Intelligence (multi-trait analysis); TGCT cis rs614226 0.935 rs2235222 chr12:120892193 G/C cg10072921 chr12:121022843 NA 0.43 4.51 0.38 1.48e-5 Type 1 diabetes nephropathy; TGCT cis rs72945132 0.882 rs7118156 chr11:70142922 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7666738 0.791 rs10005118 chr4:99038196 A/C cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1843834 1.000 rs1843834 chr2:225558042 A/G cg22455342 chr2:225449267 CUL3 0.75 7.37 0.55 2.15e-11 IgE levels in asthmatics (D.p. specific); TGCT cis rs2657888 0.931 rs2939312 chr12:56932554 G/A cg23002907 chr12:56915593 RBMS2 0.44 6.13 0.48 1.09e-8 Adiponectin levels; TGCT cis rs6815814 0.950 rs11722889 chr4:38810975 C/T cg02016764 chr4:38805732 TLR1 -0.37 -5.85 -0.47 4.08e-8 Breast cancer; TGCT cis rs6728642 0.908 rs6731522 chr2:97647997 A/G cg26665480 chr2:98280029 ACTR1B -0.92 -6.0 -0.47 2.01e-8 Bipolar disorder lithium response (continuous) or schizophrenia; TGCT cis rs10493773 0.775 rs12756013 chr1:86153532 C/T cg17807903 chr1:86174739 ZNHIT6 -0.43 -6.18 -0.49 8.29e-9 Urate levels in overweight individuals; TGCT cis rs7246657 0.943 rs2081096 chr19:37964700 G/A cg18154014 chr19:37997991 ZNF793 0.73 5.33 0.43 4.4e-7 Coronary artery calcification; TGCT cis rs3733585 0.699 rs7699609 chr4:9961059 A/G cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7666738 0.830 rs4699592 chr4:98974202 A/C cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT trans rs4332037 0.539 rs11772627 chr7:2109821 G/C cg25206134 chr2:45395956 NA 0.94 6.99 0.53 1.52e-10 Bipolar disorder; TGCT cis rs10504229 0.728 rs72650852 chr8:58150463 G/A cg08280861 chr8:58055591 NA 0.39 4.86 0.4 3.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs7085104 0.632 rs6162 chr10:104596981 G/A cg04362960 chr10:104952993 NT5C2 0.56 4.92 0.4 2.68e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7567389 0.564 rs10209483 chr2:128158637 C/T cg02161262 chr2:127865248 BIN1 -0.54 -4.75 -0.39 5.56e-6 Self-rated health; TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg14159672 chr1:205819179 PM20D1 0.71 9.63 0.65 9.76e-17 Menarche (age at onset); TGCT cis rs7914558 0.966 rs12571568 chr10:104891396 C/G cg04362960 chr10:104952993 NT5C2 0.62 5.55 0.45 1.66e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs3091242 0.933 rs932372 chr1:25755014 G/A cg00786635 chr1:25594202 NA 0.57 6.0 0.47 2e-8 Erythrocyte sedimentation rate; TGCT cis rs3796352 1.000 rs13072818 chr3:53074263 C/T cg27565382 chr3:53032988 SFMBT1 0.43 4.62 0.38 9.64e-6 Immune reponse to smallpox (secreted IL-2); TGCT trans rs1814175 0.645 rs1963215 chr11:49931486 G/A cg11707556 chr5:10655725 ANKRD33B -0.44 -10.51 -0.69 7.2e-19 Height; TGCT cis rs2486288 0.656 rs2413772 chr15:45549862 G/A cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.39e-7 Glomerular filtration rate; TGCT cis rs7584330 0.554 rs77194105 chr2:238436463 T/C cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs786425 0.585 rs2333834 chr12:124246004 G/A cg10461218 chr12:124144432 GTF2H3 0.22 4.67 0.39 7.73e-6 Pubertal anthropometrics; TGCT cis rs28374715 0.662 rs521890 chr15:41473143 C/T cg18705301 chr15:41695430 NDUFAF1 -0.74 -11.02 -0.7 4.25e-20 Ulcerative colitis; TGCT cis rs2535633 0.602 rs6801235 chr3:53009595 T/C cg10802521 chr3:52805072 NEK4 -0.52 -5.52 -0.44 1.86e-7 Body mass index; TGCT trans rs77457752 0.525 rs1923351 chr9:13898902 G/A cg23609682 chr1:3070786 PRDM16 0.5 6.79 0.52 4.09e-10 Breast cancer; TGCT cis rs6088590 1.000 rs6088590 chr20:33313566 T/C cg24642439 chr20:33292090 TP53INP2 0.69 6.17 0.48 8.94e-9 Coronary artery disease; TGCT cis rs7845219 0.539 rs10441538 chr8:95868608 G/A cg16049864 chr8:95962084 TP53INP1 -0.55 -6.29 -0.49 4.98e-9 Type 2 diabetes; TGCT cis rs7772486 0.790 rs9403756 chr6:146257761 C/G cg23711669 chr6:146136114 FBXO30 -0.86 -9.95 -0.67 1.64e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs10875746 0.903 rs2158516 chr12:48490834 T/A cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs4750440 0.637 rs2457859 chr10:14032099 T/G cg25464840 chr10:14372910 FRMD4A 0.33 4.46 0.37 1.82e-5 Adiponectin levels; TGCT cis rs9906944 0.707 rs9912906 chr17:47104432 A/T cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs763121 0.853 rs5757234 chr22:39072686 C/T cg06022373 chr22:39101656 GTPBP1 0.8 8.25 0.6 1.95e-13 Menopause (age at onset); TGCT cis rs736408 0.688 rs2239551 chr3:52818579 A/G cg10802521 chr3:52805072 NEK4 0.75 9.17 0.64 1.26e-15 Bipolar disorder; TGCT cis rs35000415 0.683 rs66872377 chr7:128722172 A/C cg06242719 chr7:129414860 MIR183;MIR96 -0.3 -4.58 -0.38 1.1e-5 Systemic lupus erythematosus; TGCT cis rs5769765 1.000 rs2319458 chr22:50236306 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.37 5.62 0.45 1.19e-7 Schizophrenia; TGCT cis rs875971 0.522 rs1880556 chr7:65432544 T/C cg00343986 chr7:65444356 GUSB 0.25 5.63 0.45 1.15e-7 Aortic root size; TGCT cis rs2730260 0.537 rs55864635 chr7:158859744 C/T cg12144100 chr7:157890277 PTPRN2 0.35 4.45 0.37 1.87e-5 Myopia (pathological); TGCT cis rs950169 0.579 rs12912716 chr15:84664263 A/T cg11189052 chr15:85197271 WDR73 0.65 5.06 0.41 1.45e-6 Schizophrenia; TGCT cis rs6882076 0.925 rs1393207 chr5:156397540 T/A cg12943317 chr5:156479607 HAVCR1 -0.31 -6.01 -0.48 1.9e-8 LDL cholesterol levels;Cholesterol, total;Total cholesterol levels;Triglycerides;LDL cholesterol; TGCT cis rs60843830 1.000 rs11553746 chr2:272203 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.73 7.41 0.55 1.74e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg02873098 chr16:4524103 NMRAL1;HMOX2 0.37 5.22 0.42 7.15e-7 Schizophrenia; TGCT cis rs2932538 0.922 rs6698030 chr1:113138318 G/A cg10983938 chr1:113465962 AFARP1;SLC16A1 0.21 4.44 0.37 1.99e-5 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs12681287 0.640 rs12550142 chr8:87471861 C/A cg27223183 chr8:87520930 FAM82B -0.89 -6.43 -0.5 2.54e-9 Caudate activity during reward; TGCT cis rs7617773 0.925 rs7374376 chr3:48172687 T/C cg11946769 chr3:48343235 NME6 -0.56 -4.84 -0.4 3.74e-6 Coronary artery disease; TGCT cis rs7769051 0.522 rs60133731 chr6:133095818 T/C cg22852734 chr6:133119734 C6orf192 1.16 4.48 0.37 1.67e-5 Type 2 diabetes nephropathy; TGCT cis rs854765 0.505 rs2955358 chr17:17946623 A/G cg09796270 chr17:17721594 SREBF1 -0.25 -4.77 -0.39 5.07e-6 Total body bone mineral density; TGCT cis rs11874712 1.000 rs9783886 chr18:43651270 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.11 0.42 1.19e-6 Migraine - clinic-based; TGCT cis rs9653442 0.564 rs6707067 chr2:100767232 G/A cg22139774 chr2:100720529 AFF3 -0.35 -5.55 -0.45 1.63e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs17376456 0.877 rs10057605 chr5:93443950 T/G cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs2204008 0.694 rs10880262 chr12:38328696 C/T cg26384229 chr12:38710491 ALG10B 0.63 5.68 0.45 9.15e-8 Bladder cancer; TGCT cis rs860295 0.580 rs2282301 chr1:155868625 A/G cg05700447 chr1:155978627 NA -0.22 -4.67 -0.39 7.64e-6 Body mass index; TGCT cis rs2637266 0.703 rs846641 chr10:78524136 C/T cg18941641 chr10:78392320 NA 0.4 4.73 0.39 5.96e-6 Pulmonary function; TGCT trans rs916888 0.697 rs199516 chr17:44856485 C/T cg22433210 chr17:43662623 NA -1.02 -7.43 -0.56 1.52e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1552244 0.554 rs3732964 chr3:10048839 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs2832191 0.716 rs1543652 chr21:30448000 G/C cg08807101 chr21:30365312 RNF160 0.65 6.13 0.48 1.06e-8 Dental caries; TGCT cis rs66573146 0.831 rs67315413 chr4:6987910 T/C cg00086871 chr4:6988644 TBC1D14 0.94 4.62 0.38 9.61e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7666738 0.791 rs7660866 chr4:98961335 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.18 0.42 8.63e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11711311 1.000 rs7622403 chr3:113472434 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 0.76 7.09 0.54 8.84e-11 IgG glycosylation; TGCT cis rs2288884 1.000 rs78543982 chr19:52550867 T/C cg13540795 chr19:52551618 ZNF432 -0.59 -5.02 -0.41 1.79e-6 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs3809566 1.000 rs10851721 chr15:63332383 T/C cg00520135 chr15:63333846 TPM1 -0.44 -5.46 -0.44 2.44e-7 Platelet count; TGCT cis rs9457247 0.967 rs388406 chr6:167409562 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.31e-6 Crohn's disease; TGCT cis rs4730430 0.515 rs6943600 chr7:110132602 G/A cg14239618 chr7:110281356 NA 0.24 4.65 0.39 8.25e-6 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs208520 1.000 rs12190187 chr6:66973207 T/G cg07460842 chr6:66804631 NA 0.81 7.16 0.54 6.31e-11 Exhaled nitric oxide output; TGCT cis rs936229 0.813 rs2168519 chr15:75080872 T/C cg10253484 chr15:75165896 SCAMP2 -0.67 -5.38 -0.43 3.64e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs2404602 0.692 rs1867197 chr15:76910031 A/G cg22467129 chr15:76604101 ETFA 0.45 5.07 0.41 1.4e-6 Blood metabolite levels; TGCT cis rs78456975 0.607 rs73909625 chr2:1541934 A/G cg01028140 chr2:1542097 TPO -0.36 -4.63 -0.38 9.02e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs7666738 0.830 rs7664169 chr4:99037859 C/T cg18180107 chr4:99064573 C4orf37 -0.56 -5.15 -0.42 9.93e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9796 0.866 rs544744 chr15:41366290 G/C cg18705301 chr15:41695430 NDUFAF1 -0.47 -6.09 -0.48 1.34e-8 Menopause (age at onset); TGCT cis rs453301 0.653 rs1045529 chr8:8890098 A/G cg00184457 chr8:8946301 NA -0.24 -4.45 -0.37 1.89e-5 Joint mobility (Beighton score); TGCT cis rs7044106 0.762 rs1867254 chr9:123429078 C/T cg09586646 chr9:123605570 PSMD5;LOC253039 0.43 4.56 0.38 1.21e-5 Hip circumference adjusted for BMI; TGCT cis rs7666738 0.791 rs4699329 chr4:99056212 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs58669269 chr7:65951953 T/C cg07424592 chr7:64974309 NA 1.29 8.01 0.58 7.16e-13 Diabetic kidney disease; TGCT cis rs853679 0.527 rs1997660 chr6:28269663 A/G cg18815343 chr6:28367644 ZSCAN12 -0.46 -4.8 -0.4 4.46e-6 Depression; TGCT cis rs7833790 0.660 rs7839178 chr8:82763479 A/G cg23324259 chr8:82754387 SNX16 0.62 4.71 0.39 6.47e-6 Diastolic blood pressure; TGCT cis rs2243480 1.000 rs313831 chr7:65551226 C/T cg18252515 chr7:66147081 NA -1.1 -7.18 -0.54 5.77e-11 Diabetic kidney disease; TGCT cis rs13108904 0.935 rs3755920 chr4:1243617 T/C cg13395646 chr4:1353034 KIAA1530 -0.39 -5.2 -0.42 7.9e-7 Obesity-related traits; TGCT cis rs10504229 1.000 rs67344620 chr8:58187537 C/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs5769707 0.935 rs5770594 chr22:50018497 G/A cg20744362 chr22:50050164 C22orf34 0.27 4.47 0.37 1.77e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs16867321 0.671 rs13429179 chr2:181492790 T/C cg23363182 chr2:181467187 NA -0.46 -4.75 -0.39 5.44e-6 Obesity; TGCT cis rs6725041 0.547 rs4672645 chr2:213204955 C/T cg16329650 chr2:213403929 ERBB4 -0.67 -5.89 -0.47 3.4e-8 QT interval (ambient particulate matter interaction); TGCT cis rs9467773 0.596 rs3001369 chr6:26670969 C/T cg15659132 chr6:26577336 NA 0.89 10.22 0.68 3.77e-18 Intelligence (multi-trait analysis); TGCT cis rs858239 0.600 rs13438188 chr7:23144197 C/T cg05602783 chr7:23145260 KLHL7 0.62 5.45 0.44 2.56e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs6700896 0.522 rs4655792 chr1:66159264 T/G cg14976592 chr1:65886160 LEPROT;LEPR 0.54 4.44 0.37 1.98e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs4566357 0.615 rs6436644 chr2:227914275 T/A cg11843606 chr2:227700838 RHBDD1 -0.54 -5.25 -0.43 6.53e-7 Coronary artery disease; TGCT cis rs79349575 0.749 rs12601672 chr17:47006493 T/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs1348850 0.914 rs10170546 chr2:178248790 C/T cg22681709 chr2:178499509 PDE11A -0.35 -4.57 -0.38 1.15e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2996428 0.709 rs6667255 chr1:3711689 T/C cg17848003 chr1:3704513 LRRC47 0.17 4.71 0.39 6.63e-6 Red cell distribution width; TGCT cis rs514406 0.861 rs4926577 chr1:53226788 C/A cg01802117 chr1:53393560 SCP2 0.43 5.13 0.42 1.1e-6 Monocyte count; TGCT cis rs589448 0.902 rs315134 chr12:69762713 G/A cg20891283 chr12:69753455 YEATS4 0.9 10.36 0.68 1.69e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs6500602 0.727 rs1477123 chr16:4560627 T/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 7.02 0.53 1.32e-10 Schizophrenia; TGCT cis rs9325144 0.647 rs34311455 chr12:39060889 C/T cg26384229 chr12:38710491 ALG10B -0.56 -5.1 -0.42 1.25e-6 Morning vs. evening chronotype; TGCT cis rs12681287 0.640 rs6471309 chr8:87387760 C/T cg27223183 chr8:87520930 FAM82B -0.89 -6.82 -0.52 3.58e-10 Caudate activity during reward; TGCT cis rs6701037 0.681 rs1894709 chr1:175132371 G/T cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT cis rs3125734 0.633 rs1835862 chr10:64056068 G/A cg19640130 chr10:64028056 RTKN2 -0.38 -4.77 -0.39 5.19e-6 Rheumatoid arthritis; TGCT cis rs7772486 0.790 rs9376968 chr6:146180364 T/C cg05347473 chr6:146136440 FBXO30 0.51 4.76 0.39 5.27e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.573 rs9306355 chr22:42111896 A/T cg17554472 chr22:41940697 POLR3H 0.45 4.84 0.4 3.72e-6 Vitiligo; TGCT trans rs941408 1.000 rs1076447 chr19:2792128 C/G cg19676328 chr12:49525230 TUBA1B -0.74 -7.15 -0.54 6.67e-11 Total cholesterol levels; TGCT cis rs1385374 1.000 rs12311303 chr12:129301592 C/T cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs138249 0.898 rs138227 chr22:50556815 A/G cg24864161 chr22:50528282 MOV10L1 0.47 5.02 0.41 1.77e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs7412746 0.658 rs17660092 chr1:150797748 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.69 0.39 7.01e-6 Melanoma; TGCT cis rs34172651 0.517 rs36113933 chr16:24838862 A/G cg06028605 chr16:24865363 SLC5A11 0.41 4.59 0.38 1.05e-5 Intelligence (multi-trait analysis); TGCT cis rs826838 0.967 rs11169387 chr12:39145737 C/T cg26384229 chr12:38710491 ALG10B 1.05 9.91 0.66 2.14e-17 Heart rate; TGCT cis rs7772486 0.641 rs2748489 chr6:146331287 T/G cg13319975 chr6:146136371 FBXO30 -0.68 -6.33 -0.49 4.17e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs66561647 1.000 rs66561647 chr8:128971861 C/T cg11792826 chr8:129160931 MIR1208 0.22 4.9 0.4 2.94e-6 Hemoglobin concentration; TGCT cis rs2245008 0.774 rs253136 chr16:83979601 A/C cg27171569 chr16:83987465 OSGIN1 -0.4 -4.59 -0.38 1.06e-5 Pursuit maintenance gain; TGCT cis rs12887734 0.524 rs4906364 chr14:104214342 C/G cg26031613 chr14:104095156 KLC1 -0.72 -6.2 -0.49 7.61e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs7772486 0.720 rs4896844 chr6:146075224 T/C cg13319975 chr6:146136371 FBXO30 0.56 4.93 0.4 2.56e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.802 rs2234058 chr22:41777883 G/A cg06481639 chr22:41940642 POLR3H -0.72 -6.52 -0.51 1.61e-9 Vitiligo; TGCT cis rs7954584 0.551 rs1169072 chr12:122401501 C/T cg21171335 chr12:122356390 WDR66 -0.62 -6.82 -0.52 3.56e-10 Mean corpuscular volume; TGCT cis rs9611565 0.729 rs9611570 chr22:41782721 G/T cg06634786 chr22:41940651 POLR3H -0.89 -8.45 -0.6 6.78e-14 Vitiligo; TGCT cis rs1691799 0.867 rs1168356 chr12:66750469 A/G cg16791601 chr12:66731901 HELB -0.27 -5.8 -0.46 5.22e-8 White blood cell count (basophil); TGCT cis rs7917772 0.582 rs12411442 chr10:104349531 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6089584 0.888 rs6061979 chr20:60617141 C/G cg13665807 chr20:60559372 TAF4 -0.46 -5.0 -0.41 1.92e-6 Body mass index; TGCT cis rs7666738 0.830 rs17026973 chr4:98680041 T/A cg17366294 chr4:99064904 C4orf37 0.62 6.4 0.5 2.94e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs4820539 1.000 rs2157710 chr22:23457486 C/T cg14186256 chr22:23484241 RTDR1 0.98 12.21 0.74 5.2e-23 Bone mineral density; TGCT cis rs7918232 0.607 rs1755401 chr10:27405763 A/C cg14442939 chr10:27389572 ANKRD26 0.82 5.9 0.47 3.26e-8 Breast cancer; TGCT cis rs78456975 0.782 rs13403265 chr2:1516836 A/G cg01028140 chr2:1542097 TPO -0.36 -4.67 -0.39 7.69e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs6448317 0.954 rs7666033 chr4:24925272 A/G cg21108841 chr4:24914750 CCDC149 -0.61 -4.85 -0.4 3.63e-6 Heschl's gyrus morphology; TGCT cis rs6430585 0.528 rs309133 chr2:136751842 A/C cg07169764 chr2:136633963 MCM6 1.2 11.66 0.72 1.14e-21 Corneal structure; TGCT cis rs6754311 0.593 rs4954279 chr2:136409073 G/A cg07169764 chr2:136633963 MCM6 0.68 5.89 0.47 3.33e-8 Mosquito bite size; TGCT cis rs858239 0.669 rs1006709 chr7:23140099 C/T cg05602783 chr7:23145260 KLHL7 -0.63 -5.32 -0.43 4.7e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs150641967 1 rs150641967 chr19:19370340 TGACA/T cg03709012 chr19:19516395 GATAD2A 1.05 4.86 0.4 3.45e-6 Triglyceride levels;Very low density lipoprotein cholesterol levels;Low density lipoprotein cholesterol;Total cholesterol levels; TGCT cis rs10779751 0.960 rs6661859 chr1:11301063 T/C cg08854313 chr1:11322531 MTOR 0.99 10.58 0.69 4.78e-19 Body mass index; TGCT cis rs7772486 0.754 rs9497401 chr6:146051271 T/C cg05347473 chr6:146136440 FBXO30 -0.51 -4.66 -0.39 8.17e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7819412 0.806 rs17723229 chr8:10930069 A/C cg21775007 chr8:11205619 TDH -0.5 -4.63 -0.38 9.11e-6 Triglycerides; TGCT cis rs7666738 0.830 rs1896154 chr4:99021161 T/C cg17366294 chr4:99064904 C4orf37 0.68 7.04 0.53 1.17e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7618915 0.524 rs12488461 chr3:52698417 T/C cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs2046867 0.862 rs6778168 chr3:72840206 T/A cg25664220 chr3:72788482 NA -0.52 -6.65 -0.51 8.27e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4144743 0.877 rs7218773 chr17:45324211 C/T cg18085866 chr17:45331354 ITGB3 -0.72 -4.8 -0.4 4.39e-6 Body mass index; TGCT cis rs74233809 0.901 rs11191416 chr10:104604916 G/T cg05855489 chr10:104503620 C10orf26 -0.81 -4.6 -0.38 1.03e-5 Birth weight; TGCT cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg00684032 chr4:1343700 KIAA1530 -0.23 -4.94 -0.41 2.48e-6 Obesity-related traits; TGCT cis rs9926296 0.585 rs8058009 chr16:89856439 G/A cg02609749 chr16:89786786 C16orf7;ZNF276 0.35 4.94 0.41 2.44e-6 Vitiligo; TGCT cis rs713587 0.713 rs4665276 chr2:25213333 C/T cg15423357 chr2:25149977 NA -0.58 -5.91 -0.47 3.05e-8 Body mass index in non-asthmatics; TGCT cis rs4713118 0.581 rs200504 chr6:27785820 T/C cg10876282 chr6:28092338 ZSCAN16 0.59 4.83 0.4 3.89e-6 Parkinson's disease; TGCT cis rs7429990 0.803 rs11714518 chr3:48156635 T/C cg11946769 chr3:48343235 NME6 -0.56 -4.61 -0.38 9.72e-6 Educational attainment (years of education); TGCT cis rs11650494 0.908 rs75904857 chr17:47370449 T/G cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs13118159 0.550 rs28614045 chr4:1374695 C/A cg16405210 chr4:1374714 KIAA1530 -0.24 -4.51 -0.38 1.49e-5 Longevity; TGCT cis rs941873 0.835 rs10762859 chr10:81103370 T/A cg09469691 chr10:81107165 PPIF 0.56 5.55 0.45 1.67e-7 Height; TGCT cis rs9457247 1.000 rs386548 chr6:167385533 A/T cg23791538 chr6:167370224 RNASET2 0.48 4.8 0.4 4.52e-6 Crohn's disease; TGCT cis rs2762353 0.935 rs2328895 chr6:25802083 C/T cg12310025 chr6:25882481 NA -0.53 -5.45 -0.44 2.58e-7 Blood metabolite levels; TGCT cis rs9388451 0.839 rs3966775 chr6:126067655 C/A cg05901451 chr6:126070800 HEY2 -1.04 -15.78 -0.82 1.89e-31 Brugada syndrome; TGCT cis rs12477438 0.520 rs13798 chr2:99813614 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.06 0.84 2.55e-34 Chronic sinus infection; TGCT cis rs9677476 0.955 rs9973370 chr2:232095587 A/G cg07929768 chr2:232055508 NA 0.3 4.48 0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs11112613 1.000 rs11112613 chr12:106003786 A/G cg03607813 chr12:105948248 NA 0.47 5.0 0.41 1.9e-6 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7586879 0.639 rs2384058 chr2:25100328 A/G cg01884057 chr2:25150051 NA 0.33 6.36 0.5 3.53e-9 Body mass index; TGCT cis rs7568458 0.709 rs1446669 chr2:85762209 T/C cg02493740 chr2:85810744 VAMP5 -0.29 -5.58 -0.45 1.42e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7824557 0.564 rs2043508 chr8:11227406 G/A cg21775007 chr8:11205619 TDH -0.65 -6.14 -0.48 1.01e-8 Retinal vascular caliber; TGCT cis rs10832963 0.924 rs10832950 chr11:18635815 A/G cg09201001 chr11:18656081 SPTY2D1 1.05 11.63 0.72 1.34e-21 Breast cancer; TGCT cis rs9926296 0.581 rs2108838 chr16:89904426 A/G cg08627397 chr16:89984028 MC1R -0.34 -5.43 -0.44 2.79e-7 Vitiligo; TGCT cis rs6089829 0.962 rs7273930 chr20:61666017 G/A cg03213289 chr20:61660250 NA 0.72 10.83 0.7 1.22e-19 Prostate cancer (SNP x SNP interaction); TGCT cis rs2836974 0.897 rs2836923 chr21:40524236 T/C cg11644478 chr21:40555479 PSMG1 1.05 10.98 0.7 5.12e-20 Cognitive function; TGCT cis rs9372253 1.000 rs9374170 chr6:110712991 A/G cg19196401 chr6:110721138 DDO -0.48 -7.05 -0.53 1.1e-10 Platelet distribution width; TGCT cis rs514406 0.536 rs878957 chr1:53197559 C/T cg22166914 chr1:53195759 ZYG11B -0.46 -7.97 -0.58 8.69e-13 Monocyte count; TGCT cis rs28595532 1.000 rs56000725 chr4:119637675 G/A cg21605333 chr4:119757512 SEC24D 1.36 7.39 0.55 1.89e-11 Cannabis dependence symptom count; TGCT cis rs10197940 0.624 rs4461258 chr2:152429679 A/G cg06191203 chr2:152266755 RIF1 0.78 7.61 0.56 5.94e-12 Lung cancer; TGCT cis rs6921919 0.583 rs740621 chr6:28397787 A/G cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.06 -0.41 1.48e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs79349575 0.756 rs4793605 chr17:47035869 T/C cg27201301 chr17:47039149 GIP 0.25 4.47 0.37 1.72e-5 Type 2 diabetes; TGCT cis rs2243480 1.000 rs34193460 chr7:65393110 A/G cg18252515 chr7:66147081 NA -1.14 -6.81 -0.52 3.76e-10 Diabetic kidney disease; TGCT cis rs7178572 0.568 rs4886850 chr15:77404160 G/C cg15453836 chr15:77711506 NA -0.4 -4.52 -0.38 1.45e-5 Type 2 diabetes; TGCT cis rs3776081 0.600 rs11167497 chr5:149533976 G/T cg18424208 chr5:149546337 CDX1 -0.25 -4.48 -0.37 1.66e-5 Blood protein levels; TGCT cis rs9443645 0.901 rs4706079 chr6:79615208 G/A cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs8179 0.553 rs42377 chr7:92243672 G/A cg15732164 chr7:92237376 CDK6 -0.24 -4.52 -0.38 1.45e-5 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs7100689 0.646 rs2994390 chr10:82074395 C/A cg01528321 chr10:82214614 TSPAN14 0.72 7.28 0.55 3.37e-11 Post bronchodilator FEV1; TGCT cis rs4242434 0.927 rs35952885 chr8:22491622 T/G cg03733263 chr8:22462867 KIAA1967 1.14 17.32 0.84 6.76e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs17253792 0.822 rs75016910 chr14:56050466 C/G cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs10479542 0.892 rs7736163 chr5:178980316 G/C cg09060608 chr5:178986726 RUFY1 0.49 5.59 0.45 1.35e-7 Lung cancer; TGCT cis rs3820928 0.845 rs1917126 chr2:227840923 G/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs1799949 1.000 rs11658754 chr17:41292739 G/A cg23758822 chr17:41437982 NA 0.72 6.81 0.52 3.77e-10 Menopause (age at onset); TGCT cis rs2463822 1.000 rs2463820 chr11:62112290 A/T cg06239285 chr11:62104954 ASRGL1 0.89 5.91 0.47 3.04e-8 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs12142240 0.698 rs17361805 chr1:46813967 C/T cg00530320 chr1:46809349 NSUN4 0.29 5.95 0.47 2.53e-8 Menopause (age at onset); TGCT cis rs367943 0.901 rs171180 chr5:112817093 A/C cg12552261 chr5:112820674 MCC -0.24 -4.91 -0.4 2.81e-6 Type 2 diabetes; TGCT cis rs9660180 0.846 rs10907195 chr1:1713348 C/T cg20999797 chr1:1681921 NA -0.2 -5.09 -0.42 1.27e-6 Body mass index; TGCT trans rs4332037 0.586 rs62442944 chr7:2015047 T/G cg25206134 chr2:45395956 NA 0.97 7.33 0.55 2.6e-11 Bipolar disorder; TGCT cis rs2153535 0.542 rs915354 chr6:8440357 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.56 0.45 1.55e-7 Motion sickness; TGCT cis rs1541995 1.000 rs4984608 chr15:96335890 A/G cg00882281 chr15:96346592 NA 0.28 4.53 0.38 1.39e-5 Photic sneeze reflex; TGCT cis rs6089829 1.000 rs62207535 chr20:61669187 A/G cg03213289 chr20:61660250 NA 0.69 9.79 0.66 4.07e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs7746199 0.668 rs7749305 chr6:27446566 T/C cg02458000 chr6:26745757 NA -0.94 -4.46 -0.37 1.82e-5 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs57590327 0.508 rs13093082 chr3:81949958 C/T cg07356753 chr3:81810745 GBE1 -0.74 -6.82 -0.52 3.5e-10 Extraversion; TGCT cis rs2204008 0.837 rs8189467 chr12:38241956 T/C cg26384229 chr12:38710491 ALG10B 0.84 7.28 0.55 3.29e-11 Bladder cancer; TGCT cis rs9467773 1.000 rs1884946 chr6:26545308 C/G cg26531700 chr6:26746687 NA 0.47 4.56 0.38 1.19e-5 Intelligence (multi-trait analysis); TGCT cis rs11969893 0.850 rs9498414 chr6:101322976 C/T cg12253828 chr6:101329408 ASCC3 1.08 5.14 0.42 1.06e-6 Economic and political preferences (immigration/crime); TGCT cis rs7811142 0.830 rs1063945 chr7:99930447 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.05 8.68 0.61 1.9e-14 Platelet count; TGCT cis rs4252435 0.614 rs78357866 chr7:142629280 T/G cg21621906 chr7:142494914 NA -1.09 -4.56 -0.38 1.22e-5 Cancer; TGCT cis rs12530134 1.000 rs12530134 chr6:170919470 G/A cg16639145 chr6:170041015 WDR27 0.58 5.12 0.42 1.11e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs3796352 1.000 rs58660500 chr3:53086573 C/T cg15956490 chr3:53032818 SFMBT1 0.6 6.78 0.52 4.31e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1670533 1.000 rs1010342 chr4:1068819 C/T cg20887711 chr4:1340912 KIAA1530 0.64 5.16 0.42 9.64e-7 Recombination rate (females); TGCT cis rs116095464 0.558 rs7710005 chr5:233572 A/G cg22857025 chr5:266934 NA -0.34 -6.64 -0.51 8.6e-10 Breast cancer; TGCT cis rs10504229 0.728 rs78765835 chr8:58154337 A/G cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs7954584 0.546 rs10840630 chr12:122352445 C/T cg13699009 chr12:122356056 WDR66 0.29 5.73 0.46 7.13e-8 Mean corpuscular volume; TGCT cis rs12497850 0.931 rs4974079 chr3:48906469 T/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs4665809 0.652 rs2241739 chr2:26411894 C/T cg25036284 chr2:26402008 FAM59B -0.67 -5.42 -0.44 3.04e-7 Gut microbiome composition (summer); TGCT cis rs12477438 0.520 rs6756650 chr2:99801800 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs6831352 0.838 rs2851250 chr4:100044113 G/C cg12011299 chr4:100065546 ADH4 0.43 5.02 0.41 1.71e-6 Alcohol dependence; TGCT cis rs2404602 0.692 rs4886829 chr15:77091182 G/T cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.21e-6 Blood metabolite levels; TGCT cis rs9372498 0.536 rs72952761 chr6:118866758 A/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT cis rs4786125 0.879 rs11645781 chr16:6896128 C/T cg03623568 chr16:6915990 A2BP1 0.35 4.83 0.4 3.87e-6 Heart rate variability traits (SDNN); TGCT cis rs4285028 0.699 rs1920297 chr3:121598000 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.78 -6.72 -0.52 5.95e-10 Multiple sclerosis; TGCT cis rs514406 0.505 rs269290 chr1:53167027 A/T cg01802117 chr1:53393560 SCP2 -0.42 -4.84 -0.4 3.86e-6 Monocyte count; TGCT cis rs10114408 0.959 rs1890380 chr9:96665812 G/A cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9325144 0.647 rs11169258 chr12:39113040 C/T cg26384229 chr12:38710491 ALG10B -0.6 -5.65 -0.45 1.03e-7 Morning vs. evening chronotype; TGCT cis rs11085466 0.615 rs76695906 chr19:21766710 G/A cg02997983 chr19:21646781 NA -0.63 -4.53 -0.38 1.35e-5 Colorectal or endometrial cancer; TGCT cis rs2832191 0.740 rs6516890 chr21:30476812 T/A cg08807101 chr21:30365312 RNF160 0.64 6.01 0.48 1.91e-8 Dental caries; TGCT cis rs11864453 0.647 rs9932062 chr16:72136055 T/C cg14768367 chr16:72042858 DHODH 0.52 5.27 0.43 5.78e-7 Fibrinogen levels; TGCT trans rs1499614 1.000 rs34250985 chr7:66161062 A/T cg07424592 chr7:64974309 NA 1.41 8.04 0.59 6.2e-13 Gout; TGCT trans rs1814175 0.817 rs28502006 chr11:50049930 T/C cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs9911578 0.935 rs117819974 chr17:57002324 C/T cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs4665809 1.000 rs11126375 chr2:26344787 G/A cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs910316 1.000 rs175425 chr14:75626131 T/C cg08847533 chr14:75593920 NEK9 -0.92 -9.96 -0.67 1.6e-17 Height; TGCT trans rs6762477 0.748 rs11717349 chr3:50223977 C/T cg21659725 chr3:3221576 CRBN -0.65 -7.35 -0.55 2.37e-11 Menarche (age at onset); TGCT cis rs55823223 0.564 rs58363746 chr17:73850819 C/T cg08125733 chr17:73851984 WBP2 0.87 8.8 0.62 1e-14 Psoriasis; TGCT cis rs875971 0.862 rs937494 chr7:65764678 T/A cg11764359 chr7:65958608 NA -0.57 -5.07 -0.41 1.4e-6 Aortic root size; TGCT cis rs939574 0.790 rs79225383 chr2:220093972 C/A cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.04 4.8 0.4 4.54e-6 Platelet distribution width; TGCT cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.51 0.65 1.95e-16 Cognitive function; TGCT cis rs7267979 0.844 rs1555330 chr20:25232097 A/C cg16686733 chr20:25566563 NINL 0.52 4.9 0.4 2.98e-6 Liver enzyme levels (alkaline phosphatase); TGCT trans rs7819412 0.745 rs2898260 chr8:10939490 G/T cg15556689 chr8:8085844 FLJ10661 -0.74 -7.04 -0.53 1.15e-10 Triglycerides; TGCT cis rs7772486 0.641 rs67882056 chr6:146416301 T/C cg23711669 chr6:146136114 FBXO30 0.66 6.04 0.48 1.66e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2228479 0.541 rs9806913 chr16:89953773 A/G cg06558623 chr16:89946397 TCF25 0.42 5.09 0.42 1.29e-6 Skin colour saturation; TGCT cis rs1799949 1.000 rs8176126 chr17:41259049 A/G cg05368731 chr17:41323189 NBR1 -1.19 -14.04 -0.78 2.15e-27 Menopause (age at onset); TGCT cis rs6988636 1.000 rs13260318 chr8:124190165 C/G cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9399135 0.967 rs4896120 chr6:135293512 C/G cg24558204 chr6:135376177 HBS1L 0.48 4.79 0.39 4.76e-6 Red blood cell count; TGCT trans rs6561151 0.957 rs2121034 chr13:44473866 G/T cg12856521 chr11:46389249 DGKZ 0.67 7.47 0.56 1.22e-11 Crohn's disease; TGCT cis rs6089584 0.925 rs35683654 chr20:60625401 G/T cg13665807 chr20:60559372 TAF4 0.51 5.25 0.43 6.3e-7 Body mass index; TGCT cis rs2762353 0.574 rs16890999 chr6:25755583 A/G cg03517284 chr6:25882590 NA 0.78 8.11 0.59 4.26e-13 Blood metabolite levels; TGCT cis rs4824093 0.610 rs58671506 chr22:50288983 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.48 4.93 0.41 2.53e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs864537 0.676 rs2988279 chr1:167419839 G/A cg22356347 chr1:167427500 CD247 -0.21 -5.28 -0.43 5.51e-7 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs3806843 0.608 rs155364 chr5:140346468 T/A cg09824255 chr5:140014002 CD14 0.25 4.59 0.38 1.09e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs9534288 0.843 rs4362286 chr13:46566514 G/A cg15192986 chr13:46630673 CPB2 -0.53 -7.62 -0.56 5.82e-12 Blood protein levels; TGCT cis rs4953076 0.533 rs10173126 chr2:44446492 T/C cg04920474 chr2:44395004 PPM1B 0.6 6.07 0.48 1.43e-8 Height; TGCT cis rs801193 0.569 rs6978178 chr7:66123084 G/A cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs4478858 0.684 rs7549245 chr1:31752187 A/G cg07478791 chr1:31886160 SERINC2 -0.49 -4.91 -0.4 2.82e-6 Alcohol dependence; TGCT cis rs7103648 0.643 rs12365079 chr11:47696596 A/T cg20307385 chr11:47447363 PSMC3 0.83 7.81 0.57 2.1e-12 Diastolic blood pressure;Systolic blood pressure; TGCT cis rs1552244 1.000 rs9809061 chr3:10085130 C/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs6061231 0.518 rs639836 chr20:60926223 G/A cg24112000 chr20:60950667 NA 0.34 4.76 0.39 5.24e-6 Colorectal cancer; TGCT cis rs933688 1.000 rs6867091 chr5:90734333 C/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 9.55 0.65 1.59e-16 Smoking behavior; TGCT cis rs12134133 1.000 rs4844588 chr1:207429668 T/C cg02152968 chr1:207494213 CD55 0.61 4.83 0.4 3.92e-6 Posterior cortical atrophy and Alzheimer's disease;Blood protein levels; TGCT cis rs4665809 0.941 rs7602922 chr2:26265782 C/T cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs4389656 0.857 rs274715 chr5:6723429 C/T cg10857441 chr5:6722123 POLS 0.22 4.74 0.39 5.75e-6 Coronary artery disease; TGCT cis rs709400 0.663 rs1467561 chr14:103994961 T/C cg12935359 chr14:103987150 CKB -0.4 -6.07 -0.48 1.45e-8 Body mass index; TGCT cis rs7618915 0.547 rs2336542 chr3:52710636 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs734999 1.000 rs2016366 chr1:2513678 A/T cg18854424 chr1:2615690 NA 0.44 5.33 0.43 4.46e-7 Ulcerative colitis; TGCT cis rs858239 0.806 rs10268610 chr7:23274764 A/G cg05602783 chr7:23145260 KLHL7 -0.65 -4.92 -0.4 2.64e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs1541995 0.824 rs16975550 chr15:96257703 C/A cg00882281 chr15:96346592 NA 0.29 4.58 0.38 1.11e-5 Photic sneeze reflex; TGCT cis rs7666738 0.791 rs1115615 chr4:99006614 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.51 0.44 1.97e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6089584 0.889 rs6142923 chr20:60596617 C/T cg06108461 chr20:60628389 TAF4 0.64 9.5 0.65 2.08e-16 Body mass index; TGCT cis rs453301 0.658 rs13271797 chr8:8885954 G/A cg06636001 chr8:8085503 FLJ10661 -0.69 -5.67 -0.45 9.36e-8 Joint mobility (Beighton score); TGCT cis rs17401966 0.800 rs12725210 chr1:10416993 G/A cg19773385 chr1:10388646 KIF1B -0.23 -5.38 -0.44 3.57e-7 Hepatocellular carcinoma; TGCT cis rs3862260 0.509 rs7552885 chr1:120164966 C/T cg11530693 chr1:120165357 ZNF697 0.21 4.75 0.39 5.48e-6 Systemic lupus erythematosus; TGCT cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs2832191 0.511 rs7278227 chr21:30482707 C/T cg24692254 chr21:30365293 RNF160 -0.59 -5.71 -0.46 8.06e-8 Dental caries; TGCT cis rs13256369 1.000 rs7843488 chr8:8576217 C/T cg06671706 chr8:8559999 CLDN23 0.35 4.69 0.39 7e-6 Obesity-related traits; TGCT cis rs2288884 0.806 rs11084142 chr19:52587917 A/G cg13540795 chr19:52551618 ZNF432 -0.64 -5.42 -0.44 2.98e-7 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT trans rs7618501 1.000 rs11130218 chr3:49752372 C/T cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs35306767 0.953 rs12259801 chr10:959306 C/G cg20503657 chr10:835505 NA 0.68 9.49 0.65 2.12e-16 Eosinophil percentage of granulocytes; TGCT cis rs10791097 0.506 rs10750446 chr11:130706918 T/C cg14779329 chr11:130786720 SNX19 -0.29 -5.01 -0.41 1.81e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4455778 0.659 rs4538815 chr7:49024084 A/G cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs7267979 0.764 rs2474767 chr20:25246733 T/C cg14121845 chr20:25566513 NINL 0.45 4.8 0.4 4.44e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1903068 0.819 rs10517343 chr4:56002267 T/A cg09978860 chr4:56023921 NA 0.57 6.47 0.5 2.1e-9 Endometriosis; TGCT cis rs875971 1.000 rs9986696 chr7:65704576 C/A cg18876405 chr7:65276391 NA -0.32 -4.94 -0.41 2.46e-6 Aortic root size; TGCT cis rs7937682 0.632 rs12785809 chr11:111776055 T/A cg09085632 chr11:111637200 PPP2R1B 0.84 7.34 0.55 2.4e-11 Primary sclerosing cholangitis; TGCT cis rs1552244 0.543 rs28719585 chr3:10050813 T/C cg00149659 chr3:10157352 C3orf10 0.69 4.99 0.41 2.03e-6 Alzheimer's disease; TGCT cis rs875971 1.000 rs2220626 chr7:65546062 C/T cg18876405 chr7:65276391 NA -0.35 -5.31 -0.43 4.85e-7 Aortic root size; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg24846343 chr22:24311635 DDTL 0.23 5.93 0.47 2.76e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs10504229 1.000 rs57186557 chr8:58177277 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs10479542 0.784 rs4701132 chr5:178985270 A/G cg22764044 chr5:178986830 RUFY1 -0.5 -5.78 -0.46 5.77e-8 Lung cancer; TGCT cis rs6430585 0.528 rs7573555 chr2:136694905 C/T cg07169764 chr2:136633963 MCM6 -1.19 -12.51 -0.75 1e-23 Corneal structure; TGCT cis rs62007496 0.562 rs2234137 chr14:103597322 A/G cg01937803 chr14:103605307 NA 0.64 4.9 0.4 2.9e-6 Language performance in older adults (adjusted for episodic memory); TGCT trans rs6089829 0.962 rs9680064 chr20:61666168 G/A cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs7818688 0.697 rs11779698 chr8:95979764 C/G cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7119 0.651 rs8041398 chr15:77839173 A/G cg27398640 chr15:77910606 LINGO1 -0.27 -5.12 -0.42 1.15e-6 Type 2 diabetes; TGCT cis rs10507380 0.766 rs9507877 chr13:27903933 G/T cg25543773 chr13:27185723 WASF3 0.31 4.49 0.37 1.6e-5 Electrocardiographic traits; TGCT cis rs1059312 1.000 rs2291350 chr12:129283711 G/A cg09035930 chr12:129282057 SLC15A4 0.59 11.76 0.73 6.45e-22 Systemic lupus erythematosus; TGCT cis rs5167 0.566 rs2075618 chr19:45495668 G/C cg13119609 chr19:45449297 APOC2 0.23 4.65 0.39 8.26e-6 Blood protein levels; TGCT cis rs910316 1.000 rs175426 chr14:75624134 C/T cg23033748 chr14:75592666 NEK9 -0.28 -4.75 -0.39 5.63e-6 Height; TGCT cis rs72781680 0.716 rs72788284 chr2:24097539 A/G cg08917208 chr2:24149416 ATAD2B 0.83 5.18 0.42 8.54e-7 Lymphocyte counts; TGCT cis rs2204008 0.749 rs10880692 chr12:38592918 C/G cg13010199 chr12:38710504 ALG10B -0.68 -5.44 -0.44 2.75e-7 Bladder cancer; TGCT cis rs1403694 0.515 rs822362 chr3:186453065 A/C cg12454167 chr3:186435060 KNG1 0.44 6.91 0.53 2.24e-10 Blood protein levels; TGCT cis rs3820068 0.603 rs72647128 chr1:15963908 T/C cg05660106 chr1:15850417 CASP9 0.83 8.19 0.59 2.78e-13 Systolic blood pressure; TGCT cis rs7666738 0.830 rs7678557 chr4:99057329 A/G cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6500602 0.627 rs1641866 chr16:4593040 A/C cg08645402 chr16:4508243 NA 0.2 4.91 0.4 2.76e-6 Schizophrenia; TGCT cis rs35306767 0.953 rs12357633 chr10:957246 C/T cg26597838 chr10:835615 NA 0.75 10.39 0.68 1.43e-18 Eosinophil percentage of granulocytes; TGCT cis rs9911578 0.904 rs7209253 chr17:56908987 C/T cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs8177253 0.829 rs9882812 chr3:133506127 A/G cg01448562 chr3:133502909 NA -0.34 -7.01 -0.53 1.33e-10 Iron status biomarkers; TGCT trans rs57221529 0.766 rs12519763 chr5:559145 C/T cg11887960 chr12:57824829 NA 1.15 9.35 0.64 4.71e-16 Lung disease severity in cystic fibrosis; TGCT cis rs7552404 0.691 rs61770550 chr1:76366966 C/T cg03433033 chr1:76189801 ACADM 0.77 7.43 0.56 1.5e-11 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9372253 0.678 rs9372251 chr6:110700656 A/G cg13266496 chr6:110720918 DDO -0.39 -4.53 -0.38 1.37e-5 Platelet distribution width; TGCT cis rs7226408 0.857 rs72887035 chr18:34474461 A/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7659604 0.676 rs4516739 chr4:122699741 G/T cg19748678 chr4:122722346 EXOSC9 0.84 8.99 0.63 3.42e-15 Type 2 diabetes; TGCT cis rs17221829 0.733 rs2388105 chr11:89355317 A/G cg02982614 chr11:89391479 FOLH1B 0.27 4.67 0.39 7.62e-6 Anxiety in major depressive disorder; TGCT cis rs763121 0.853 rs5750630 chr22:38985818 A/C cg06022373 chr22:39101656 GTPBP1 0.76 7.43 0.56 1.52e-11 Menopause (age at onset); TGCT cis rs4366490 1.000 rs9665846 chr11:62907832 G/A cg21002970 chr11:62369079 MTA2 0.87 4.69 0.39 6.98e-6 Conotruncal heart defects; TGCT cis rs5167 0.566 rs934427 chr19:45478816 T/G cg09555818 chr19:45449301 APOC2 0.23 4.58 0.38 1.13e-5 Blood protein levels; TGCT cis rs8078723 0.933 rs55846942 chr17:38164470 G/A cg17467752 chr17:38218738 THRA 0.54 5.22 0.42 7.25e-7 C-reactive protein and white blood cell count;Neutrophil count;White blood cell count;White blood cell count (neutrophil); TGCT cis rs2469997 1.000 rs2447176 chr8:120356892 G/A cg00681363 chr8:120844660 TAF2 0.72 4.69 0.39 7.2e-6 Hypertension (SNP x SNP interaction); TGCT cis rs28830936 0.510 rs11070349 chr15:42085017 A/C cg17847044 chr15:42102381 MAPKBP1 -0.19 -5.28 -0.43 5.6e-7 Diastolic blood pressure; TGCT cis rs524023 1.000 rs11602903 chr11:64358241 A/T cg07733098 chr11:64478343 NRXN2 0.31 4.63 0.38 8.93e-6 Urate levels in obese individuals; TGCT cis rs651907 0.557 rs2303474 chr3:101371899 G/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.64 0.69 3.59e-19 Colorectal cancer; TGCT cis rs4665809 1.000 rs2384323 chr2:26306473 C/T cg04944784 chr2:26401820 FAM59B -0.68 -6.13 -0.48 1.1e-8 Gut microbiome composition (summer); TGCT cis rs1062177 1.000 rs62377945 chr5:151208004 C/G cg12924095 chr5:151150029 G3BP1 0.36 5.18 0.42 8.79e-7 Preschool internalizing problems; TGCT cis rs12421382 0.690 rs2716049 chr11:109609889 A/C cg16359550 chr11:109292809 C11orf87 0.5 4.91 0.4 2.85e-6 Schizophrenia; TGCT trans rs6089829 0.816 rs6062397 chr20:61668268 A/G cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs1008375 0.864 rs4698196 chr4:17574735 T/C cg18681998 chr4:17616180 MED28 0.82 7.35 0.55 2.37e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs56011263 0.687 rs4690292 chr4:703712 A/G cg20735989 chr4:730612 PCGF3 -0.25 -5.49 -0.44 2.21e-7 White blood cell count; TGCT cis rs9911578 1.000 rs4793950 chr17:56593111 T/C cg12560992 chr17:57184187 TRIM37 -0.76 -9.34 -0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT cis rs4808199 1.000 rs7258508 chr19:19475469 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.68 4.98 0.41 2.12e-6 Nonalcoholic fatty liver disease; TGCT cis rs10057188 0.933 rs11948106 chr5:77894746 G/T cg07379703 chr5:78279424 ARSB -0.19 -4.45 -0.37 1.87e-5 Pulse pressure; TGCT trans rs4332037 0.950 rs62442895 chr7:1936938 G/A cg25206134 chr2:45395956 NA 1.1 9.34 0.64 5.11e-16 Bipolar disorder; TGCT cis rs986417 0.786 rs76632048 chr14:60846934 G/A cg27398547 chr14:60952738 C14orf39 -1.37 -8.31 -0.6 1.44e-13 Gut microbiota (bacterial taxa); TGCT cis rs2197308 0.813 rs11504316 chr12:38219320 G/A cg26384229 chr12:38710491 ALG10B -0.52 -4.5 -0.37 1.57e-5 Morning vs. evening chronotype; TGCT cis rs12220238 1.000 rs10824096 chr10:75937554 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs10504229 0.861 rs116964504 chr8:58185354 A/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6912958 1.000 rs6933587 chr6:88175577 T/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.59 -5.63 -0.45 1.15e-7 Monocyte percentage of white cells; TGCT cis rs9611565 0.765 rs767593 chr22:41779971 G/T cg06481639 chr22:41940642 POLR3H -0.74 -6.53 -0.51 1.49e-9 Vitiligo; TGCT cis rs4803468 1.000 rs284650 chr19:41927129 A/G cg09537434 chr19:41945824 ATP5SL -0.92 -10.57 -0.69 5.19e-19 Height; TGCT cis rs12210905 0.688 rs12215386 chr6:27406877 G/T cg08851530 chr6:28072375 NA 1.34 6.07 0.48 1.44e-8 Hip circumference adjusted for BMI; TGCT cis rs61931739 0.534 rs10844828 chr12:34303109 C/T cg06521331 chr12:34319734 NA -0.35 -5.77 -0.46 5.94e-8 Morning vs. evening chronotype; TGCT cis rs2677744 0.719 rs877285 chr15:91452204 A/G cg22570213 chr15:91497863 RCCD1 0.39 4.52 0.38 1.41e-5 Attention deficit hyperactivity disorder; TGCT cis rs514406 0.698 rs576891 chr1:53364976 A/G cg01802117 chr1:53393560 SCP2 -0.44 -5.52 -0.44 1.86e-7 Monocyte count; TGCT cis rs3096299 0.586 rs4572400 chr16:89533516 T/A cg08392591 chr16:89556376 ANKRD11 0.51 4.48 0.37 1.67e-5 Multiple myeloma (IgH translocation); TGCT cis rs1862618 0.853 rs190414 chr5:56116772 C/A cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs1538970 1.000 rs9326141 chr1:45828943 A/G cg05343316 chr1:45956843 TESK2 -0.64 -4.94 -0.41 2.49e-6 Platelet count; TGCT cis rs9910055 0.530 rs11652651 chr17:42302907 A/G cg19774624 chr17:42201019 HDAC5 0.73 7.74 0.57 2.94e-12 Total body bone mineral density; TGCT cis rs1552244 1.000 rs61077902 chr3:10126153 T/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.95 6.11 0.48 1.17e-8 Alzheimer's disease; TGCT cis rs10493389 0.673 rs11208758 chr1:66287200 A/G cg08716655 chr1:66257732 PDE4B -0.42 -4.56 -0.38 1.23e-5 Echocardiographic traits; TGCT cis rs35264875 0.851 rs72930621 chr11:68866745 C/T cg02660097 chr11:68866761 NA 0.31 4.49 0.37 1.63e-5 Blond vs. brown hair color; TGCT cis rs13064411 0.696 rs869342 chr3:113226330 C/T cg10517650 chr3:113235015 CCDC52 -0.32 -4.45 -0.37 1.85e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT trans rs3790455 0.610 rs1171561 chr1:156455898 G/A cg16443977 chr5:115884994 SEMA6A 0.39 6.66 0.51 8.1e-10 Migraine; TGCT cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg00786635 chr1:25594202 NA 0.57 6.0 0.47 2.02e-8 Erythrocyte sedimentation rate; TGCT cis rs3806843 0.932 rs2563269 chr5:140136468 G/T cg19875535 chr5:140030758 IK -0.37 -6.3 -0.49 4.75e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs1475911 1.000 rs2839465 chr21:43511232 C/T cg19766460 chr21:43528205 UMODL1;C21orf128 0.51 7.02 0.53 1.3e-10 IgG glycosylation; TGCT cis rs911555 0.755 rs55742283 chr14:103942965 A/G cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs7659604 0.540 rs10024878 chr4:122665451 C/G cg19748678 chr4:122722346 EXOSC9 -0.47 -4.59 -0.38 1.06e-5 Type 2 diabetes; TGCT cis rs2862064 1.000 rs2902128 chr5:156421347 C/T cg12943317 chr5:156479607 HAVCR1 -0.42 -5.62 -0.45 1.22e-7 Platelet count; TGCT cis rs751728 0.687 rs943479 chr6:33752013 A/G cg13859433 chr6:33739653 LEMD2 -0.33 -5.75 -0.46 6.65e-8 Crohn's disease; TGCT cis rs2760061 0.819 rs708120 chr1:228207651 G/C cg18477163 chr1:228402036 OBSCN 0.34 7.24 0.55 4.1e-11 Diastolic blood pressure; TGCT cis rs12142240 0.698 rs6679898 chr1:46820589 A/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs57994353 0.897 rs55824202 chr9:139357273 A/T cg13741927 chr9:139327495 INPP5E -0.26 -5.95 -0.47 2.51e-8 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs2847281 0.761 rs478582 chr18:12835976 T/C cg23598886 chr18:12777645 NA 0.4 4.77 0.39 5.13e-6 C-reactive protein levels;Esophageal cancer (squamous cell); TGCT cis rs10504229 0.517 rs75486476 chr8:58056079 G/T cg21724239 chr8:58056113 NA 0.45 6.59 0.51 1.14e-9 Developmental language disorder (linguistic errors); TGCT cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg25036284 chr2:26402008 FAM59B -0.61 -4.9 -0.4 2.92e-6 Gut microbiome composition (summer); TGCT cis rs9910055 0.529 rs575798 chr17:42181796 A/C cg13607699 chr17:42295918 UBTF -0.65 -5.39 -0.44 3.34e-7 Total body bone mineral density; TGCT cis rs651907 0.557 rs62284198 chr3:101474699 G/A cg12386194 chr3:101231763 SENP7 0.49 4.69 0.39 7.17e-6 Colorectal cancer; TGCT cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg27454412 chr7:1067447 C7orf50 0.58 4.45 0.37 1.88e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9910055 0.529 rs615070 chr17:42176591 A/G cg13607699 chr17:42295918 UBTF 0.58 4.87 0.4 3.32e-6 Total body bone mineral density; TGCT cis rs751728 0.664 rs943475 chr6:33749978 C/T cg13859433 chr6:33739653 LEMD2 0.32 5.68 0.45 9.23e-8 Crohn's disease; TGCT cis rs6671200 0.688 rs4950024 chr1:95713499 A/G cg03123541 chr1:95699097 RWDD3 -0.81 -7.26 -0.55 3.81e-11 Stearic acid (18:0) levels; TGCT cis rs28386778 0.897 rs2727333 chr17:61876023 G/A cg26338869 chr17:61819248 STRADA -0.55 -4.99 -0.41 1.98e-6 Prudent dietary pattern; TGCT cis rs4713118 0.666 rs2893930 chr6:27738806 T/C cg20933634 chr6:27740509 NA 0.35 4.83 0.4 3.92e-6 Parkinson's disease; TGCT cis rs9467711 1.000 rs6908156 chr6:26322861 C/T cg03517284 chr6:25882590 NA -0.86 -4.67 -0.39 7.69e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs739496 0.615 rs3809276 chr12:112073916 A/G cg10833066 chr12:111807467 FAM109A 0.36 5.15 0.42 9.76e-7 Platelet count; TGCT cis rs9467773 0.620 rs2494692 chr6:26615223 G/A cg15659132 chr6:26577336 NA 0.85 10.93 0.7 7e-20 Intelligence (multi-trait analysis); TGCT cis rs986417 1.000 rs6573316 chr14:61058029 C/A cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs6500602 0.727 rs4786509 chr16:4568769 C/G cg08645402 chr16:4508243 NA -0.19 -5.3 -0.43 5.14e-7 Schizophrenia; TGCT trans rs1005277 0.579 rs2504143 chr10:38383706 C/T cg17830980 chr10:43048298 ZNF37B -0.85 -10.98 -0.7 5.08e-20 Extrinsic epigenetic age acceleration; TGCT cis rs875971 0.862 rs4718319 chr7:65652784 C/A cg11764359 chr7:65958608 NA -0.56 -5.06 -0.41 1.45e-6 Aortic root size; TGCT cis rs231513 0.911 rs231476 chr17:41985845 A/G cg26893861 chr17:41843967 DUSP3 -0.76 -5.44 -0.44 2.67e-7 Cognitive function; TGCT cis rs67385638 1.000 rs11036474 chr11:5275178 T/C cg12559170 chr11:5275217 HBG2 0.46 8.09 0.59 4.52e-13 Hemoglobin levels; TGCT cis rs67311347 0.955 rs73078170 chr3:40483947 C/T cg17264618 chr3:40429014 ENTPD3 0.34 4.67 0.39 7.68e-6 Renal cell carcinoma; TGCT cis rs2243480 1.000 rs60683927 chr7:65394768 T/C cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs11783469 0.524 rs13250995 chr8:23329985 G/A cg00472375 chr8:23315376 ENTPD4 0.69 5.22 0.42 7.38e-7 Reticulocyte count; TGCT cis rs875971 0.862 rs4236208 chr7:65749078 C/T cg11764359 chr7:65958608 NA -0.57 -5.07 -0.41 1.4e-6 Aortic root size; TGCT trans rs1814175 0.935 rs11040438 chr11:49622521 G/A cg15704280 chr7:45808275 SEPT13 -0.61 -6.8 -0.52 4.02e-10 Height; TGCT cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg16325326 chr1:53192061 ZYG11B -0.84 -11.96 -0.73 2.15e-22 Monocyte count; TGCT cis rs7208859 0.673 rs73265633 chr17:29236306 G/T cg18442181 chr17:29233375 C17orf42 -0.78 -4.61 -0.38 9.8200000000000008e-06 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9291683 0.566 rs13144709 chr4:10044182 C/T cg00071950 chr4:10020882 SLC2A9 0.57 6.47 0.5 2.01e-9 Bone mineral density; TGCT cis rs6752107 0.967 rs11680130 chr2:234157258 G/A cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.21 5.0 0.41 1.87e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs11971779 0.715 rs55714903 chr7:139074590 T/C cg07862535 chr7:139043722 LUC7L2 0.71 5.55 0.45 1.63e-7 Diisocyanate-induced asthma; TGCT cis rs4372836 1.000 rs11690423 chr2:28951537 G/C cg09522027 chr2:28974177 PPP1CB 0.59 5.14 0.42 1.03e-6 Body mass index; TGCT cis rs453301 0.624 rs2288671 chr8:8860894 T/C cg06636001 chr8:8085503 FLJ10661 0.8 7.08 0.54 9.32e-11 Joint mobility (Beighton score); TGCT cis rs9611565 0.592 rs9611613 chr22:41961831 T/C cg13695892 chr22:41940480 POLR3H -0.87 -8.17 -0.59 2.95e-13 Vitiligo; TGCT trans rs2688608 1.000 rs2675680 chr10:75658864 T/C cg13918328 chr10:52500089 ASAH2B 0.65 6.68 0.51 7.29e-10 Inflammatory bowel disease; TGCT cis rs1843834 0.539 rs6713629 chr2:225410973 A/T cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs10267417 0.514 rs2072184 chr7:19748883 A/G cg07541023 chr7:19748670 TWISTNB 1.22 11.09 0.71 2.84e-20 Night sleep phenotypes; TGCT cis rs7772486 0.558 rs9376965 chr6:146130055 G/A cg13319975 chr6:146136371 FBXO30 -0.69 -6.28 -0.49 5.18e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs79349575 0.783 rs62075838 chr17:46996432 C/T cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs7674212 0.556 rs34475639 chr4:103954851 C/T cg16532752 chr4:104119610 CENPE -0.59 -5.29 -0.43 5.43e-7 Type 2 diabetes; TGCT cis rs907683 0.559 rs4674394 chr2:220289870 C/T cg15015639 chr2:220282977 DES -0.4 -4.98 -0.41 2.09e-6 Resting heart rate; TGCT cis rs5167 0.789 rs204467 chr19:45491174 A/G cg09555818 chr19:45449301 APOC2 -0.22 -4.81 -0.4 4.27e-6 Blood protein levels; TGCT cis rs6121246 0.865 rs6089055 chr20:30324045 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.84 0.4 3.79e-6 Mean corpuscular hemoglobin; TGCT cis rs597539 0.652 rs611046 chr11:68631704 A/G cg04772025 chr11:68637568 NA 0.6 6.76 0.52 4.74e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6586163 0.872 rs7082101 chr10:90741615 C/A cg03111039 chr10:90751583 FAS;ACTA2 -0.36 -4.47 -0.37 1.76e-5 Chronic lymphocytic leukemia; TGCT cis rs2730245 0.593 rs842699 chr7:158663404 T/A cg11984989 chr7:158649758 WDR60 1.07 9.87 0.66 2.58e-17 Height; TGCT cis rs7582180 0.764 rs1967341 chr2:100924559 T/C cg14675211 chr2:100938903 LONRF2 0.51 4.93 0.4 2.61e-6 Intelligence (multi-trait analysis); TGCT cis rs9972944 0.729 rs6504348 chr17:63763049 C/T cg07283582 chr17:63770753 CCDC46 -0.26 -5.24 -0.43 6.6e-7 Total body bone mineral density; TGCT cis rs7260538 0.773 rs1552223 chr19:41525952 A/G cg20630647 chr19:41531805 NA -0.27 -4.44 -0.37 1.94e-5 DDT metabolite (p,p'-DDE levels); TGCT cis rs16957091 0.647 rs7181859 chr15:43158239 A/G cg17935677 chr15:44119062 WDR76 0.53 4.69 0.39 7.11e-6 MGMT methylation in smokers; TGCT cis rs7666738 0.830 rs4699580 chr4:98930673 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs939574 0.790 rs72955440 chr2:220091765 A/C cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.11 5.34 0.43 4.31e-7 Platelet distribution width; TGCT cis rs6840360 0.606 rs2724550 chr4:152358986 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs10883723 0.810 rs7092622 chr10:104249919 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs10751667 0.600 rs10794342 chr11:924904 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.09 -0.59 4.69e-13 Alzheimer's disease (late onset); TGCT cis rs806215 0.906 rs806195 chr7:127249178 A/G cg25922125 chr7:127225783 GCC1 0.59 5.98 0.47 2.21e-8 Type 2 diabetes; TGCT cis rs7010267 0.570 rs35746859 chr8:120039139 G/C cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs2549003 0.934 rs2549006 chr5:131827065 A/G cg02551604 chr5:131831745 NA 0.86 10.72 0.69 2.18e-19 Asthma (sex interaction); TGCT cis rs6964587 0.610 rs4729008 chr7:91457054 G/T cg17063962 chr7:91808500 NA 0.73 6.65 0.51 8.52e-10 Breast cancer; TGCT cis rs1862618 0.853 rs252919 chr5:56124111 T/C cg24531977 chr5:56204891 C5orf35 -0.77 -7.61 -0.56 5.83e-12 Initial pursuit acceleration; TGCT cis rs7726839 0.540 rs12520279 chr5:657291 T/C cg20362242 chr5:692897 TPPP 0.51 4.49 0.37 1.61e-5 Obesity-related traits; TGCT cis rs6964587 1.000 rs9690208 chr7:91735613 T/A cg17063962 chr7:91808500 NA 0.87 9.34 0.64 4.87e-16 Breast cancer; TGCT cis rs12477438 0.520 rs11123766 chr2:99780915 C/T cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 13.05 0.76 4.93e-25 Chronic sinus infection; TGCT cis rs7618915 0.501 rs6617 chr3:52740182 C/G cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.85e-10 Bipolar disorder; TGCT trans rs1814175 0.645 rs11040699 chr11:50023798 C/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.84 -0.7 1.13e-19 Height; TGCT cis rs1784581 0.855 rs1893101 chr6:162384371 G/C cg17173639 chr6:162384350 PARK2 -0.5 -9.31 -0.64 6.05e-16 Itch intensity from mosquito bite; TGCT cis rs7017914 0.934 rs1993862 chr8:71579362 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs12908161 0.959 rs11637728 chr15:85203392 A/T cg12863693 chr15:85201151 NMB 0.44 5.22 0.42 7.28e-7 Schizophrenia; TGCT cis rs3782455 1.000 rs117171899 chr12:114403070 G/A cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT trans rs1814175 0.817 rs7947526 chr11:49983654 T/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs1153858 1.000 rs28679834 chr15:45616206 C/T cg26924012 chr15:45694286 SPATA5L1 1.04 13.01 0.76 6.06e-25 Homoarginine levels; TGCT cis rs1729951 0.575 rs835641 chr3:136703474 G/T cg12473912 chr3:136751656 NA 0.39 6.18 0.48 8.68e-9 Neuroticism; TGCT cis rs4862750 0.872 rs7671914 chr4:187878165 A/G cg03452623 chr4:187889614 NA -0.35 -5.26 -0.43 6e-7 Lobe attachment (rater-scored or self-reported); TGCT trans rs561341 1.000 rs484175 chr17:30309041 G/A cg20587970 chr11:113659929 NA -1.04 -12.57 -0.75 6.97e-24 Hip circumference adjusted for BMI; TGCT cis rs9527 0.662 rs743575 chr10:104594906 T/G cg04362960 chr10:104952993 NT5C2 0.62 5.39 0.44 3.37e-7 Arsenic metabolism; TGCT trans rs12623360 1.000 rs871946 chr2:116824113 A/T cg24136780 chr7:2158430 MAD1L1 -0.62 -6.9 -0.53 2.32e-10 Urate levels (BMI interaction); TGCT cis rs2456568 0.606 rs11020616 chr11:93691594 C/T cg17595323 chr11:93583763 C11orf90 0.41 5.02 0.41 1.78e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2688608 1.000 rs2675680 chr10:75658864 T/C cg23231163 chr10:75533350 FUT11 -0.26 -4.67 -0.39 7.77e-6 Inflammatory bowel disease; TGCT cis rs2562456 0.920 rs2650784 chr19:21666597 T/C cg01304269 chr19:21688519 ZNF429 -0.57 -4.76 -0.39 5.32e-6 Pain; TGCT cis rs7698623 0.717 rs4693193 chr4:88797992 T/C cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs7772486 0.875 rs10457794 chr6:146415608 A/G cg23711669 chr6:146136114 FBXO30 0.91 9.95 0.67 1.67e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs9308731 0.563 rs11899831 chr2:111932694 G/A cg04202892 chr2:111875749 ACOXL 0.46 5.14 0.42 1.02e-6 Chronic lymphocytic leukemia; TGCT cis rs4808199 0.894 rs9304960 chr19:19465529 G/A cg03709012 chr19:19516395 GATAD2A 0.81 6.32 0.49 4.32e-9 Nonalcoholic fatty liver disease; TGCT cis rs11098499 1.000 rs12506395 chr4:120185094 C/T cg24670566 chr4:120433619 PDE5A 0.23 4.58 0.38 1.1e-5 Corneal astigmatism; TGCT cis rs7666738 0.830 rs10021709 chr4:99030587 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs10540 0.908 rs71487293 chr11:486414 G/A cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs131805 0.794 rs131813 chr22:50961169 A/G cg25309564 chr22:51001381 C22orf41 0.56 4.86 0.4 3.55e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs394563 0.591 rs805026 chr6:149728254 G/C cg03678062 chr6:149772716 ZC3H12D -0.39 -4.85 -0.4 3.61e-6 Dupuytren's disease; TGCT cis rs12142240 0.698 rs12385695 chr1:46819021 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs1008375 1.000 rs10019856 chr4:17615742 T/A cg10189774 chr4:17578691 LAP3 0.65 5.6 0.45 1.34e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4972806 0.775 rs2857534 chr2:177035676 G/T cg13092806 chr2:177043255 NA 0.55 4.79 0.4 4.58e-6 IgG glycosylation; TGCT cis rs2760061 0.626 rs1636192 chr1:228124688 A/G cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs4563143 0.514 rs55727361 chr19:29300415 A/T cg12756686 chr19:29218302 NA 0.67 5.16 0.42 9.34e-7 Methadone dose in opioid dependence; TGCT cis rs4788570 0.686 rs9937511 chr16:71815913 C/T cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs921968 0.613 rs2710251 chr2:219543433 T/C cg02176678 chr2:219576539 TTLL4 -0.33 -4.45 -0.37 1.91e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs7552404 0.924 rs7535991 chr1:76162624 C/T cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs3780486 0.846 rs10113903 chr9:33122645 C/G cg04842962 chr6:43655489 MRPS18A -1.21 -15.02 -0.8 1.08e-29 IgG glycosylation; TGCT cis rs8070128 0.601 rs8080602 chr17:17954728 G/C cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs4523957 0.651 rs1994883 chr17:2083881 T/A cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2012796 0.956 rs7146802 chr14:81820515 A/G cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs9952991 0.941 rs2542150 chr18:12779763 G/C cg23598886 chr18:12777645 NA 0.62 5.9 0.47 3.25e-8 Inflammatory skin disease; TGCT cis rs7937682 0.681 rs2156580 chr11:111394328 C/G cg09085632 chr11:111637200 PPP2R1B 0.51 4.61 0.38 1e-5 Primary sclerosing cholangitis; TGCT cis rs8038465 0.638 rs12591473 chr15:73967485 A/T cg15420318 chr15:73925796 NPTN 0.72 8.19 0.59 2.66e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9611565 0.694 rs202631 chr22:41863423 A/G cg06481639 chr22:41940642 POLR3H 0.74 6.48 0.5 1.97e-9 Vitiligo; TGCT cis rs3782455 0.793 rs2290799 chr12:114404208 G/A cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs950169 0.840 rs12905223 chr15:85114268 T/C cg12863693 chr15:85201151 NMB 0.39 4.44 0.37 1.99e-5 Schizophrenia; TGCT cis rs9393692 0.905 rs9357004 chr6:26303319 A/G cg13736514 chr6:26305472 NA -0.42 -5.9 -0.47 3.23e-8 Educational attainment; TGCT cis rs3771570 1.000 rs62193202 chr2:242303717 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs9653442 0.900 rs6754937 chr2:100827720 T/G cg07810366 chr2:100720526 AFF3 -0.4 -5.98 -0.47 2.17e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs10782582 0.586 rs5745383 chr1:76288590 G/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs704 0.790 rs13469 chr17:26676135 C/T cg10342447 chr17:26645325 TMEM97 -0.53 -5.12 -0.42 1.14e-6 Osteoprotegerin levels; TGCT cis rs763121 0.853 rs4821798 chr22:39021165 T/C cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg19454999 chr17:41278357 BRCA1;NBR2 0.51 5.37 0.43 3.71e-7 Menopause (age at onset); TGCT cis rs8072100 0.905 rs11651766 chr17:45574931 G/T cg10024583 chr17:45772800 TBKBP1 0.43 4.47 0.37 1.74e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs910316 0.763 rs175490 chr14:75545685 A/G cg08847533 chr14:75593920 NEK9 0.84 8.37 0.6 1.02e-13 Height; TGCT cis rs2839186 0.564 rs4819215 chr21:47623573 G/A cg13012494 chr21:47604986 C21orf56 0.38 4.49 0.37 1.58e-5 Testicular germ cell tumor; TGCT cis rs9807989 0.524 rs6759479 chr2:103040047 A/C cg03938978 chr2:103052716 IL18RAP 0.27 5.41 0.44 3.17e-7 Asthma; TGCT cis rs9818758 0.607 rs9837625 chr3:49215966 C/T cg00383909 chr3:49044727 WDR6 1.29 6.62 0.51 9.88e-10 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7926906 0.713 rs10741376 chr11:90538099 C/T cg26138821 chr11:89956704 CHORDC1 0.45 4.46 0.37 1.79e-5 Intelligence (multi-trait analysis); TGCT cis rs797680 0.856 rs7537403 chr1:93777724 T/C cg17826107 chr1:92977322 EVI5 -0.22 -5.05 -0.41 1.53e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7267979 1.000 rs6037099 chr20:25356876 T/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs832540 0.864 rs252908 chr5:56120686 T/C cg12311346 chr5:56204834 C5orf35 -0.47 -5.03 -0.41 1.7e-6 Coronary artery disease; TGCT cis rs7412746 0.646 rs1972060 chr1:150937594 T/C cg04414720 chr1:150670196 GOLPH3L 0.38 4.5 0.37 1.52e-5 Melanoma; TGCT cis rs7916852 0.618 rs3802523 chr10:28341885 C/T cg15286905 chr10:27530250 ACBD5 -0.64 -5.01 -0.41 1.82e-6 Glaucoma (primary open-angle); TGCT cis rs7829975 0.522 rs6601689 chr8:8172283 C/T cg15556689 chr8:8085844 FLJ10661 0.63 5.87 0.47 3.74e-8 Mood instability; TGCT cis rs13188771 0.651 rs3846602 chr5:100884294 C/A cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs6725041 0.757 rs9973677 chr2:213080994 C/T cg20637307 chr2:213403960 ERBB4 -0.51 -4.48 -0.37 1.68e-5 QT interval (ambient particulate matter interaction); TGCT cis rs2404602 0.716 rs1946650 chr15:76848463 T/C cg26408565 chr15:76604113 ETFA -0.4 -5.23 -0.43 6.98e-7 Blood metabolite levels; TGCT cis rs4081724 0.565 rs7251505 chr19:33802542 G/A cg18823272 chr19:34111733 CHST8 0.4 4.45 0.37 1.86e-5 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2456568 0.900 rs877340 chr11:93689292 A/T cg14065697 chr11:93583672 C11orf90 -0.38 -4.52 -0.38 1.4e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10875746 0.903 rs3782911 chr12:48483492 T/G cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs763121 0.853 rs8140617 chr22:38970439 A/G cg06022373 chr22:39101656 GTPBP1 -0.72 -6.8 -0.52 3.97e-10 Menopause (age at onset); TGCT cis rs6674176 0.611 rs12737898 chr1:44407401 C/G cg12908607 chr1:44402522 ARTN -0.69 -4.6 -0.38 1.03e-5 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs3796352 1.000 rs113995589 chr3:53132372 A/T cg27565382 chr3:53032988 SFMBT1 0.4 4.44 0.37 1.94e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7267979 1.000 rs2424700 chr20:25266513 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs5750830 0.649 rs5750811 chr22:39793066 G/T cg24399712 chr22:39784796 NA 0.97 11.25 0.71 1.14e-20 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.679 rs75402323 chr8:58136227 A/G cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs2224391 0.628 rs2773307 chr6:5244290 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs910187 0.678 rs6124967 chr20:45813624 T/C cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs7312933 0.558 rs7305397 chr12:42850058 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.51 4.82 0.4 4.13e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs56235845 0.694 rs6860069 chr5:176755841 C/T cg16006841 chr5:176797999 RGS14 0.51 7.35 0.55 2.35e-11 Hemoglobin concentration;Hematocrit; TGCT cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg02725872 chr8:58115012 NA -0.38 -4.76 -0.39 5.39e-6 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.580 rs9393023 chr6:8469994 T/G cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7647973 0.626 rs6809879 chr3:49834571 A/G cg05785598 chr3:49045655 WDR6 -0.42 -5.24 -0.43 6.67e-7 Menarche (age at onset); TGCT cis rs9993613 0.808 rs16848143 chr4:73441573 C/T cg15102770 chr4:73434591 ADAMTS3 0.51 4.59 0.38 1.07e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs10984561 0.881 rs73540226 chr9:122250588 C/T cg14242995 chr9:122249943 NA 0.73 5.96 0.47 2.46e-8 Pulmonary function decline; TGCT cis rs11690935 1.000 rs1554166 chr2:172541609 G/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.58 -0.75 6.59e-24 Schizophrenia; TGCT cis rs2120019 1.000 rs34237279 chr15:75361121 A/G cg09165964 chr15:75287851 SCAMP5 -1.16 -9.78 -0.66 4.33e-17 Blood trace element (Zn levels); TGCT cis rs8141529 0.732 rs2269577 chr22:29196757 G/C cg02153584 chr22:29168773 CCDC117 0.71 6.08 0.48 1.41e-8 Lymphocyte counts; TGCT cis rs12533831 0.654 rs2435609 chr7:150890073 C/T cg04712895 chr7:150801789 AGAP3 -0.23 -4.73 -0.39 6.12e-6 Childhood ear infection; TGCT cis rs2153535 0.541 rs6908504 chr6:8456778 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs7226408 0.595 rs72887010 chr18:34460257 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2708977 1.000 rs13029764 chr2:97328874 C/T cg01950434 chr2:97203154 ARID5A -0.61 -5.54 -0.45 1.76e-7 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs9894429 0.789 rs35887231 chr17:79587126 G/A cg21984481 chr17:79567631 NPLOC4 -0.26 -4.9 -0.4 2.91e-6 Eye color traits; TGCT trans rs916888 0.773 rs199535 chr17:44822662 A/G cg22968622 chr17:43663579 NA 1.25 10.99 0.7 4.93e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9858542 0.537 rs34915642 chr3:49358646 G/A cg08550065 chr3:50336684 HYAL3;NAT6 0.66 4.66 0.39 7.87e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7178572 0.524 rs1473922 chr15:77656798 G/T cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs28595532 0.920 rs115683389 chr4:119735557 T/G cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT trans rs916888 0.821 rs70602 chr17:44859715 T/C cg01341218 chr17:43662625 NA -1.11 -9.34 -0.64 5.11e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9611565 0.512 rs132767 chr22:42009520 C/T cg03806693 chr22:41940476 POLR3H -0.99 -9.99 -0.67 1.35e-17 Vitiligo; TGCT cis rs1538970 0.961 rs7553318 chr1:45843086 A/G cg05343316 chr1:45956843 TESK2 0.65 5.14 0.42 1.06e-6 Platelet count; TGCT cis rs17376456 0.877 rs10073039 chr5:93467709 A/G cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs5769707 0.681 rs8140095 chr22:50043795 A/G cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 4.99e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs6831352 0.918 rs29001214 chr4:100051733 A/G cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs7949030 1.000 rs7949030 chr11:62394881 A/G cg13298116 chr11:62369859 EML3;MTA2 0.56 7.85 0.58 1.69e-12 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3617 0.625 rs2535633 chr3:52859630 C/G cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.59 -0.38 1.08e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.753 rs17027308 chr4:99091088 T/A cg05340658 chr4:99064831 C4orf37 0.5 5.51 0.44 2.02e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6500602 0.727 rs4238849 chr16:4538114 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.3 5.56 0.45 1.61e-7 Schizophrenia; TGCT cis rs4654899 0.758 rs7521711 chr1:21400218 A/G cg01072550 chr1:21505969 NA -0.56 -9.15 -0.63 1.42e-15 Superior frontal gyrus grey matter volume; TGCT cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg22121687 chr7:65037720 NA -0.81 -5.03 -0.41 1.7e-6 Diabetic kidney disease; TGCT cis rs7829975 0.511 rs1401390 chr8:8136410 C/T cg08975724 chr8:8085496 FLJ10661 0.53 4.64 0.38 8.6e-6 Mood instability; TGCT cis rs1008375 0.932 rs3846356 chr4:17614176 C/T cg16339924 chr4:17578868 LAP3 0.74 5.88 0.47 3.64e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3848445 1.000 rs7214411 chr17:14288990 C/T cg05091736 chr17:14942129 NA -0.53 -4.48 -0.37 1.7e-5 Protein quantitative trait loci; TGCT cis rs2992756 1.000 rs2992756 chr1:18807339 T/C cg05040210 chr1:18807594 KLHDC7A -0.26 -4.46 -0.37 1.83e-5 Breast cancer; TGCT cis rs116095464 1.000 rs6555160 chr5:311669 A/G cg03604011 chr5:400201 AHRR 0.53 4.64 0.38 8.84e-6 Breast cancer; TGCT cis rs9611565 0.765 rs132909 chr22:41802031 G/A cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs9831754 0.856 rs9824624 chr3:78407182 G/A cg06138941 chr3:78371609 NA -0.48 -5.2 -0.42 7.84e-7 Calcium levels; TGCT cis rs2153535 0.580 rs9328483 chr6:8521295 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT trans rs12599106 0.792 rs12597352 chr16:34638507 A/T cg21548813 chr6:291882 DUSP22 -0.64 -6.74 -0.52 5.2e-10 Menopause (age at onset); TGCT cis rs137603 0.562 rs470080 chr22:39712368 C/T cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.84 -0.4 3.78e-6 Primary biliary cholangitis; TGCT trans rs7618501 1.000 rs57648519 chr3:49813169 C/A cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs539096 0.566 rs3011220 chr1:44308867 A/G cg12908607 chr1:44402522 ARTN -0.66 -7.92 -0.58 1.18e-12 Intelligence (multi-trait analysis); TGCT trans rs10506458 0.834 rs73127067 chr12:63390333 G/T cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.54 -0.56 8.62e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs17270561 1.000 rs12211184 chr6:25823774 G/A cg15022984 chr6:26056706 HIST1H1C -0.73 -4.6 -0.38 1.02e-5 Iron status biomarkers; TGCT cis rs2276314 0.762 rs3826600 chr18:33609053 A/G cg19628046 chr18:33552617 C18orf21 0.51 4.46 0.37 1.79e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs8129326 0.805 rs9984075 chr21:35784117 T/A cg27150370 chr21:34863940 DNAJC28 -0.47 -4.61 -0.38 9.86e-6 Cancer; TGCT cis rs9297145 0.585 rs10953283 chr7:98782750 A/G cg05967295 chr7:98741636 SMURF1 0.69 8.57 0.61 3.4e-14 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs17376456 0.825 rs6877030 chr5:93201841 C/A cg25358565 chr5:93447407 FAM172A 0.98 7.67 0.57 4.38e-12 Diabetic retinopathy; TGCT cis rs13326165 0.715 rs7643570 chr3:52373792 G/T cg27565382 chr3:53032988 SFMBT1 0.37 4.93 0.41 2.55e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs514406 0.861 rs562182 chr1:53270010 C/T cg08859206 chr1:53392774 SCP2 -0.41 -6.17 -0.48 9e-9 Monocyte count; TGCT cis rs6665290 0.904 rs1045252 chr1:227181555 A/G cg10327440 chr1:227177885 CDC42BPA -0.99 -20.27 -0.88 3.54e-41 Myeloid white cell count; TGCT cis rs7659604 0.539 rs11731917 chr4:122783233 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.35 -5.31 -0.43 4.79e-7 Type 2 diabetes; TGCT cis rs7586879 0.796 rs916484 chr2:25082588 A/C cg01884057 chr2:25150051 NA 0.26 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs546131 0.928 rs553789 chr11:34827579 G/A cg06937548 chr11:34938143 PDHX;APIP 0.65 5.91 0.47 3.14e-8 Lung disease severity in cystic fibrosis; TGCT cis rs7927771 0.832 rs1542321 chr11:47379615 G/A cg21462715 chr11:47870315 NUP160 -0.55 -4.47 -0.37 1.78e-5 Subjective well-being; TGCT cis rs4843747 0.519 rs12599755 chr16:88107006 A/G cg06915872 chr16:87998081 BANP -0.29 -4.46 -0.37 1.81e-5 Menopause (age at onset); TGCT cis rs2663905 0.706 rs2683260 chr15:81385552 A/C cg18028999 chr15:81426610 C15orf26 -0.72 -6.43 -0.5 2.49e-9 QT interval (drug interaction); TGCT cis rs7771547 0.642 rs12214285 chr6:36434679 C/T cg07856975 chr6:36356162 ETV7 -0.2 -4.58 -0.38 1.11e-5 Platelet distribution width; TGCT cis rs7811142 0.830 rs61735533 chr7:99955866 G/A cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.19 0.42 8.33e-7 Platelet count; TGCT cis rs17076896 0.786 rs61956083 chr13:19935217 C/T cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs4631830 0.863 rs2611489 chr10:51524889 C/T cg10326726 chr10:51549505 MSMB -0.25 -4.84 -0.4 3.72e-6 Prostate-specific antigen levels; TGCT cis rs10089 1.000 rs11957052 chr5:127524055 T/C cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.25e-5 Ileal carcinoids; TGCT cis rs7772486 0.686 rs857880 chr6:145971115 T/C cg05347473 chr6:146136440 FBXO30 -0.49 -4.59 -0.38 1.06e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs453301 0.686 rs11787026 chr8:8902371 A/T cg06636001 chr8:8085503 FLJ10661 0.68 5.54 0.45 1.75e-7 Joint mobility (Beighton score); TGCT cis rs2535633 0.631 rs2465101 chr3:52991307 A/T cg10802521 chr3:52805072 NEK4 0.54 5.73 0.46 7.03e-8 Body mass index; TGCT cis rs6951245 0.745 rs79788515 chr7:1101079 C/T cg27454412 chr7:1067447 C7orf50 0.61 4.75 0.39 5.6e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7020830 0.867 rs563132 chr9:37245476 A/T cg14294708 chr9:37120828 ZCCHC7 1.12 14.94 0.8 1.71e-29 Schizophrenia; TGCT cis rs1903068 0.886 rs1551644 chr4:55994266 A/T cg16572876 chr4:56024045 NA 0.45 5.08 0.42 1.34e-6 Endometriosis; TGCT cis rs7824557 0.767 rs1897951 chr8:11169854 C/T cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs7772486 0.719 rs702317 chr6:146005010 C/T cg23711669 chr6:146136114 FBXO30 -0.93 -10.83 -0.7 1.24e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6951245 1.000 rs78628466 chr7:1068453 G/C cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17253792 0.822 rs28754619 chr14:56088394 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs4746818 1.000 rs4746818 chr10:70884687 G/T cg04149295 chr10:70884716 VPS26A 0.71 5.07 0.41 1.4e-6 Left atrial antero-posterior diameter; TGCT cis rs11792861 0.926 rs72607166 chr9:111821530 A/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.49 4.52 0.38 1.45e-5 Menarche (age at onset); TGCT cis rs877282 1.000 rs11253370 chr10:773712 G/A cg17470449 chr10:769945 NA 0.3 4.79 0.39 4.71e-6 Uric acid levels; TGCT cis rs2692947 0.727 rs893173 chr2:96789787 T/C cg22654517 chr2:96458247 NA 0.23 4.97 0.41 2.18e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs6988636 0.892 rs58116120 chr8:124191776 T/G cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs2072499 0.966 rs2853641 chr1:156181770 A/G cg25208724 chr1:156163844 SLC25A44 1.1 16.06 0.82 4.53e-32 Testicular germ cell tumor; TGCT cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs617219 0.737 rs6453431 chr5:78493873 G/C cg05890484 chr5:78407552 BHMT 0.36 4.93 0.41 2.53e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2235642 0.787 rs2235646 chr16:1601287 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.31 -5.3 -0.43 5.12e-7 Coronary artery disease; TGCT cis rs78487399 0.808 rs6737882 chr2:43731908 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.77 -0.39 4.99e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9916302 0.706 rs8182252 chr17:37727950 T/C cg07936489 chr17:37558343 FBXL20 0.87 6.95 0.53 1.85e-10 Glomerular filtration rate (creatinine); TGCT cis rs12497850 0.764 rs6784111 chr3:49178846 T/C cg07636037 chr3:49044803 WDR6 0.94 9.88 0.66 2.51e-17 Parkinson's disease; TGCT cis rs1158570 0.500 rs2670890 chr8:131314923 G/A cg16277922 chr8:131349729 ASAP1 -0.46 -5.85 -0.46 4.14e-8 Platelet count; TGCT cis rs3770081 1.000 rs13390702 chr2:86237935 C/T cg23655155 chr2:86332777 POLR1A;PTCD3 -1.17 -4.75 -0.39 5.63e-6 Facial emotion recognition (sad faces); TGCT cis rs8177179 0.904 rs1130459 chr3:133465283 A/G cg24879335 chr3:133465180 TF 0.36 4.82 0.4 4.16e-6 Iron status biomarkers (transferrin levels); TGCT cis rs28374715 0.532 rs28535540 chr15:41659277 G/A cg18705301 chr15:41695430 NDUFAF1 -0.92 -15.84 -0.82 1.44e-31 Ulcerative colitis; TGCT cis rs7674212 0.541 rs2720471 chr4:104023840 A/G cg16532752 chr4:104119610 CENPE -0.59 -5.13 -0.42 1.06e-6 Type 2 diabetes; TGCT cis rs2120019 1.000 rs1867146 chr15:75354971 C/G cg17294928 chr15:75287854 SCAMP5 -0.84 -6.3 -0.49 4.75e-9 Blood trace element (Zn levels); TGCT trans rs4650994 1.000 rs4650994 chr1:178515312 A/G cg05059571 chr16:84539110 KIAA1609 0.41 7.67 0.57 4.32e-12 HDL cholesterol levels;HDL cholesterol; TGCT cis rs763014 0.898 rs916416 chr16:632198 T/A cg27436995 chr16:743998 FBXL16 -0.45 -4.82 -0.4 4.17e-6 Height; TGCT cis rs4808199 1.000 rs4808199 chr19:19545099 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.64 4.57 0.38 1.15e-5 Nonalcoholic fatty liver disease; TGCT cis rs1862618 0.853 rs832569 chr5:56154584 T/A cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs35150201 0.818 rs7810260 chr7:135311120 G/A cg23117316 chr7:135346802 PL-5283 -0.48 -5.21 -0.42 7.48e-7 Plateletcrit;Mean corpuscular hemoglobin;Mean platelet volume; TGCT cis rs1691799 0.867 rs1168330 chr12:66763167 C/T cg16791601 chr12:66731901 HELB 0.25 5.05 0.41 1.56e-6 White blood cell count (basophil); TGCT cis rs7412746 0.658 rs6669855 chr1:150861229 C/T cg09365446 chr1:150670422 GOLPH3L 0.35 5.03 0.41 1.68e-6 Melanoma; TGCT cis rs7223966 0.921 rs2006123 chr17:61958669 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.68 5.32 0.43 4.68e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs9611565 0.500 rs2011053 chr22:42121278 G/A cg06481639 chr22:41940642 POLR3H 0.56 4.87 0.4 3.39e-6 Vitiligo; TGCT cis rs10028773 0.515 rs9994488 chr4:120587781 C/T cg09307838 chr4:120376055 NA 0.56 5.36 0.43 3.87e-7 Educational attainment; TGCT cis rs7267979 1.000 rs6138575 chr20:25438952 G/A cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4273100 0.512 rs973650 chr17:19291785 A/G cg01534423 chr17:18965556 NA -0.75 -7.83 -0.58 1.83e-12 Schizophrenia; TGCT trans rs7726839 0.794 rs6883536 chr5:599274 G/A cg25482853 chr8:67687455 SGK3 0.99 7.83 0.58 1.85e-12 Obesity-related traits; TGCT cis rs10197940 0.662 rs4467261 chr2:152281391 G/C cg19508488 chr2:152266495 RIF1 0.74 6.66 0.51 7.77e-10 Lung cancer; TGCT cis rs7169223 0.653 rs8042170 chr15:79096599 G/A cg03762349 chr15:79060523 ADAMTS7 -0.25 -5.45 -0.44 2.6e-7 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs7666738 0.830 rs35752787 chr4:98935202 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10540 1.000 rs12418639 chr11:473300 A/C cg03934478 chr11:495069 RNH1 -0.36 -5.57 -0.45 1.49e-7 Body mass index; TGCT cis rs11718455 0.960 rs34179760 chr3:44002303 A/G cg08738300 chr3:44038990 NA 0.85 6.41 0.5 2.72e-9 Coronary artery disease; TGCT cis rs7937682 0.883 rs472465 chr11:111468962 C/T cg09085632 chr11:111637200 PPP2R1B -0.99 -10.02 -0.67 1.16e-17 Primary sclerosing cholangitis; TGCT cis rs9926296 0.715 rs2115401 chr16:89740609 A/G cg27121462 chr16:89883253 FANCA 0.54 5.21 0.42 7.54e-7 Vitiligo; TGCT cis rs1878931 0.555 rs27228 chr16:3431933 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.69 -5.53 -0.44 1.81e-7 Body mass index (adult); TGCT cis rs7772486 0.686 rs9386131 chr6:146121608 G/A cg05347473 chr6:146136440 FBXO30 0.47 4.48 0.37 1.7e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs1577917 0.538 rs7755996 chr6:86423720 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.52 4.65 0.39 8.34e-6 Response to antipsychotic treatment; TGCT cis rs9926296 0.632 rs7184315 chr16:89799373 C/G cg26513180 chr16:89883248 FANCA -0.69 -6.77 -0.52 4.51e-10 Vitiligo; TGCT cis rs981844 0.583 rs62325060 chr4:154630501 G/A cg14289246 chr4:154710475 SFRP2 1.02 7.78 0.57 2.45e-12 Response to statins (LDL cholesterol change); TGCT cis rs1552244 0.938 rs7652951 chr3:10063763 A/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs9910055 0.659 rs7214540 chr17:42256604 A/G cg19774624 chr17:42201019 HDAC5 -0.85 -10.09 -0.67 7.79e-18 Total body bone mineral density; TGCT cis rs713587 0.646 rs34697209 chr2:25127394 A/G cg01884057 chr2:25150051 NA 0.34 6.57 0.51 1.24e-9 Body mass index in non-asthmatics; TGCT cis rs644799 1.000 rs543530 chr11:95545170 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs74417235 0.639 rs2396994 chr5:154052750 A/T cg08754654 chr5:154026448 NA -0.59 -5.68 -0.45 9.04e-8 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs10754283 0.967 rs10922685 chr1:90118320 A/G cg03145924 chr1:90228473 NA -0.4 -4.51 -0.38 1.5e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2836974 0.965 rs9941894 chr21:40634058 C/T cg06238570 chr21:40685208 BRWD1 0.57 5.17 0.42 8.96e-7 Cognitive function; TGCT cis rs13217239 0.646 rs4403259 chr6:26997617 C/T cg26531700 chr6:26746687 NA 0.68 6.86 0.52 2.83e-10 Schizophrenia; TGCT cis rs425277 0.565 rs3128293 chr1:2065339 A/G cg12140144 chr1:2984275 FLJ42875;PRDM16 0.37 5.06 0.41 1.5e-6 Height; TGCT cis rs9902453 0.765 rs2264303 chr17:28055348 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.39 -0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs1008375 0.932 rs7697329 chr4:17657853 C/A cg18681998 chr4:17616180 MED28 0.96 10.38 0.68 1.51e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7917772 0.503 rs56219824 chr10:104302337 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6582630 0.502 rs11182760 chr12:38606273 A/T cg26384229 chr12:38710491 ALG10B 0.9 8.06 0.59 5.32e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.673 rs35009908 chr4:99110770 G/A cg17366294 chr4:99064904 C4orf37 0.76 6.13 0.48 1.08e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4927850 1.000 rs7627868 chr3:195753473 A/T cg12923728 chr3:195709715 SDHAP1 -0.36 -7.57 -0.56 7.39e-12 Pancreatic cancer; TGCT cis rs10031466 0.967 rs12647135 chr4:189011174 A/C cg04086012 chr4:189060900 TRIML1 0.22 4.9 0.4 2.89e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs1800795 0.652 rs7802307 chr7:22766433 T/A cg13104385 chr7:22767384 IL6 0.2 4.64 0.38 8.85e-6 Cerebrospinal fluid clusterin levels in APOEe4- carriers; TGCT cis rs7567389 0.671 rs72845993 chr2:128108601 T/C cg02161262 chr2:127865248 BIN1 0.52 4.72 0.39 6.35e-6 Self-rated health; TGCT cis rs17001868 0.568 rs6001894 chr22:40779197 T/C cg07138101 chr22:40742427 ADSL 0.71 5.36 0.43 3.92e-7 Mammographic density (dense area); TGCT cis rs9430161 0.611 rs2095920 chr1:11033457 T/A cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs1421811 0.532 rs17540044 chr5:32692238 C/G cg16267343 chr5:32710456 NPR3 -0.74 -6.4 -0.5 2.87e-9 Blood pressure; TGCT cis rs6089829 1.000 rs62207535 chr20:61669187 A/G cg02380750 chr20:61661411 NA 0.35 6.13 0.48 1.1e-8 Prostate cancer (SNP x SNP interaction); TGCT trans rs525455 1.000 rs2580898 chr10:13102437 T/C cg21721093 chr17:8906386 NA 0.63 6.62 0.51 9.7e-10 Platelet aggregation; TGCT cis rs73001065 0.591 rs11668386 chr19:19531910 A/G cg03709012 chr19:19516395 GATAD2A 0.9 4.9 0.4 2.99e-6 LDL cholesterol; TGCT cis rs2013441 1.000 rs2526460 chr17:20086352 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs7666738 0.791 rs2903151 chr4:99027218 T/C cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs5769765 1.000 rs5769764 chr22:50270784 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT trans rs2727020 0.729 rs1164685 chr11:49293660 G/A cg15704280 chr7:45808275 SEPT13 0.73 8.36 0.6 1.1e-13 Coronary artery disease; TGCT cis rs8072100 0.934 rs9905583 chr17:45741016 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.13 -0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4242434 0.927 rs720746 chr8:22471399 T/C cg03733263 chr8:22462867 KIAA1967 1.15 20.1 0.87 7.99e-41 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs9611565 0.659 rs1569516 chr22:41910244 C/T cg13695892 chr22:41940480 POLR3H -0.91 -8.8 -0.62 9.77e-15 Vitiligo; TGCT cis rs11190604 1.000 rs4244338 chr10:102272802 A/G cg23241863 chr10:102295624 HIF1AN 0.68 5.17 0.42 9.15e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10504229 0.683 rs11786523 chr8:58131319 G/C cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs3806843 1.000 rs3806845 chr5:140180737 C/T cg19875535 chr5:140030758 IK 0.36 6.09 0.48 1.33e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs9733 0.818 rs6694531 chr1:150683512 C/A cg13175981 chr1:150552382 MCL1 0.43 4.78 0.39 4.88e-6 Tonsillectomy; TGCT cis rs589448 0.902 rs315138 chr12:69764850 A/T cg14784868 chr12:69753453 YEATS4 0.89 10.48 0.69 8.4e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg06601766 chr17:61851465 DDX42;CCDC47 0.53 4.48 0.37 1.69e-5 Prudent dietary pattern; TGCT cis rs12541335 0.639 rs7003478 chr8:22201123 A/G cg00420450 chr8:22132641 PIWIL2 0.23 4.56 0.38 1.22e-5 Hypertriglyceridemia; TGCT cis rs1344694 0.548 rs12468812 chr2:216905867 C/T cg25588852 chr2:216877276 MREG -0.25 -4.54 -0.38 1.31e-5 Alcohol dependence; TGCT cis rs9549260 0.755 rs9549241 chr13:41210041 G/A cg21288729 chr13:41239152 FOXO1 0.99 10.47 0.69 8.86e-19 Red blood cell count; TGCT cis rs7100689 0.646 rs7081889 chr10:82165427 C/A cg01528321 chr10:82214614 TSPAN14 0.73 7.73 0.57 3.25e-12 Post bronchodilator FEV1; TGCT cis rs9926296 0.681 rs12923946 chr16:89821080 C/T cg03388025 chr16:89894329 SPIRE2 0.32 4.73 0.39 6.03e-6 Vitiligo; TGCT cis rs3820928 0.967 rs16822905 chr2:227770727 G/C cg11843606 chr2:227700838 RHBDD1 -0.53 -4.69 -0.39 7.17e-6 Pulmonary function; TGCT trans rs6089829 0.925 rs6122086 chr20:61664528 T/C cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs1949733 1.000 rs1916326 chr4:8500023 G/A cg11789530 chr4:8429930 ACOX3 -0.64 -5.95 -0.47 2.52e-8 Response to antineoplastic agents; TGCT trans rs1974653 0.672 rs76584826 chr22:20068503 G/T cg08822737 chr17:71088851 SLC39A11 -0.93 -7.61 -0.56 5.97e-12 Schizophrenia; TGCT cis rs12220238 0.722 rs7073340 chr10:76402277 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.59 4.54 0.38 1.29e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs12682352 0.652 rs3827806 chr8:8724276 C/T cg08975724 chr8:8085496 FLJ10661 0.56 5.13 0.42 1.07e-6 Neuroticism; TGCT cis rs7267979 0.586 rs11087505 chr20:25196520 T/A cg14121845 chr20:25566513 NINL 0.43 4.65 0.39 8.21e-6 Liver enzyme levels (alkaline phosphatase); TGCT trans rs6951245 0.529 rs76001997 chr7:1152615 C/T cg13565492 chr6:43139072 SRF -0.81 -7.71 -0.57 3.45e-12 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7618915 0.547 rs34215106 chr3:52659124 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.08 0.48 1.37e-8 Bipolar disorder; TGCT cis rs2932538 0.922 rs12739994 chr1:113131159 T/C cg22162597 chr1:113214053 CAPZA1 0.28 5.92 0.47 2.98e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9818758 0.607 rs73074866 chr3:49626666 C/T cg08550065 chr3:50336684 HYAL3;NAT6 1.04 5.13 0.42 1.08e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7937682 1.000 rs12363179 chr11:111568091 G/A cg09085632 chr11:111637200 PPP2R1B 1.04 9.55 0.65 1.58e-16 Primary sclerosing cholangitis; TGCT cis rs7666738 0.822 rs11097599 chr4:98959562 T/A cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2760061 0.598 rs673726 chr1:228120173 T/C cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs73198271 0.583 rs11781985 chr8:8589783 C/T cg06671706 chr8:8559999 CLDN23 0.39 4.68 0.39 7.49e-6 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9436747 0.739 rs1171267 chr1:66003854 T/G cg14976592 chr1:65886160 LEPROT;LEPR -0.5 -4.87 -0.4 3.4e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs72781680 0.716 rs2675363 chr2:24080003 G/C cg08917208 chr2:24149416 ATAD2B 0.77 4.83 0.4 3.98e-6 Lymphocyte counts; TGCT cis rs1372520 0.577 rs2737028 chr4:90717016 A/G cg01966878 chr4:90757139 SNCA -0.32 -4.84 -0.4 3.76e-6 Neuroticism; TGCT cis rs4891159 0.513 rs35534021 chr18:74130523 G/A cg24786174 chr18:74118243 ZNF516 0.66 12.82 0.76 1.76e-24 Longevity; TGCT cis rs2197308 0.623 rs1672426 chr12:38118671 C/T cg26384229 chr12:38710491 ALG10B -0.58 -5.09 -0.42 1.28e-6 Morning vs. evening chronotype; TGCT cis rs4595586 0.545 rs12827823 chr12:39392144 G/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs7618915 0.547 rs10865973 chr3:52718154 A/T cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs6964587 1.000 rs6970277 chr7:91680655 T/C cg22709100 chr7:91322751 NA 0.27 4.46 0.37 1.84e-5 Breast cancer; TGCT cis rs17767294 0.614 rs72845061 chr6:27653261 G/A cg08851530 chr6:28072375 NA 1.56 7.38 0.55 1.95e-11 Parkinson's disease; TGCT cis rs10504229 1.000 rs73607871 chr8:58173007 T/C cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs11098499 0.789 rs10212719 chr4:120254437 T/C cg09307838 chr4:120376055 NA 0.63 6.06 0.48 1.49e-8 Corneal astigmatism; TGCT cis rs1347297 0.526 rs2276617 chr2:179250397 A/G cg03991736 chr2:179345203 MIR548N;PLEKHA3 -0.49 -4.75 -0.39 5.55e-6 Alzheimer disease and age of onset; TGCT cis rs4975709 0.569 rs4975742 chr5:1858612 T/C cg07747251 chr5:1868357 NA 0.35 4.65 0.39 8.24e-6 Cardiovascular disease risk factors; TGCT cis rs4653767 0.573 rs708770 chr1:226912135 C/T cg10327440 chr1:227177885 CDC42BPA -0.4 -4.46 -0.37 1.84e-5 Parkinson's disease; TGCT cis rs1129187 0.755 rs9462856 chr6:42926024 T/C cg09436375 chr6:42928200 GNMT -0.4 -5.18 -0.42 8.58e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs853679 0.517 rs4713135 chr6:28039586 G/A cg12963246 chr6:28129442 ZNF389 0.51 4.97 0.41 2.19e-6 Depression; TGCT cis rs2067615 0.524 rs10861645 chr12:107071130 C/T cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs2762353 0.779 rs9393672 chr6:25842605 T/G cg15691649 chr6:25882328 NA -0.35 -4.67 -0.39 7.71e-6 Blood metabolite levels; TGCT cis rs3749237 0.964 rs1799843 chr3:49849723 G/A cg03060546 chr3:49711283 APEH 0.69 7.12 0.54 7.8e-11 Resting heart rate; TGCT cis rs78487399 0.614 rs77061610 chr2:43659970 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -4.54 -0.38 1.34e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4727027 0.933 rs2158633 chr7:148832652 C/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.5 4.58 0.38 1.13e-5 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs57590327 0.555 rs13088603 chr3:81791167 A/G cg07356753 chr3:81810745 GBE1 -0.77 -7.2 -0.54 5.1e-11 Extraversion; TGCT cis rs9733 0.526 rs11204696 chr1:150658721 T/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs12220238 1.000 rs11000936 chr10:75992383 A/T cg19889307 chr10:75911429 ADK;AP3M1 0.91 7.98 0.58 8.43e-13 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs2070488 0.775 rs4371464 chr3:38548021 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.74 -6.94 -0.53 1.94e-10 Electrocardiographic conduction measures; TGCT cis rs12477438 0.520 rs6741772 chr2:99738961 A/G cg14399236 chr2:99771627 LIPT1;TSGA10 0.85 8.41 0.6 8.43e-14 Chronic sinus infection; TGCT cis rs7119 0.717 rs7181283 chr15:77814544 G/A cg27398640 chr15:77910606 LINGO1 -0.25 -4.6 -0.38 1.05e-5 Type 2 diabetes; TGCT cis rs6964587 0.967 rs34040612 chr7:91798916 G/T cg17063962 chr7:91808500 NA 0.89 9.59 0.65 1.24e-16 Breast cancer; TGCT cis rs9372498 0.536 rs62422236 chr6:118972633 G/T cg21191810 chr6:118973309 C6orf204 -0.37 -4.77 -0.39 5.15e-6 Diastolic blood pressure; TGCT cis rs6582630 0.593 rs7134006 chr12:38596245 A/C cg26384229 chr12:38710491 ALG10B 0.89 7.82 0.57 2e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs1903068 0.925 rs1551641 chr4:55993915 C/T cg16572876 chr4:56024045 NA 0.45 5.08 0.42 1.34e-6 Endometriosis; TGCT cis rs2204008 0.641 rs2387810 chr12:38368875 G/T cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs7178572 0.568 rs1493700 chr15:77629060 T/C cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs2758596 0.850 rs2241110 chr1:156172487 A/G cg25208724 chr1:156163844 SLC25A44 0.83 5.04 0.41 1.61e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs7647973 1.000 rs6446275 chr3:49466871 A/G cg05785598 chr3:49045655 WDR6 -0.38 -4.5 -0.37 1.57e-5 Menarche (age at onset); TGCT cis rs13202913 0.652 rs9383578 chr6:151838192 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.72 -4.93 -0.4 2.61e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs1570884 0.516 rs2094108 chr13:50171550 G/A cg08779649 chr13:50194554 NA 0.37 5.82 0.46 4.74e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs9929218 0.953 rs11075696 chr16:68731365 A/G cg01251360 chr16:68772225 CDH1 0.29 4.6 0.38 1.01e-5 Colorectal cancer; TGCT cis rs67311347 1.000 rs12630072 chr3:40517190 T/G cg13409248 chr3:40428643 ENTPD3 0.56 4.45 0.37 1.91e-5 Renal cell carcinoma; TGCT cis rs9611565 0.838 rs4239894 chr22:41745548 C/G cg06481639 chr22:41940642 POLR3H -0.73 -6.45 -0.5 2.27e-9 Vitiligo; TGCT cis rs12142240 0.660 rs72890715 chr1:46852077 A/G cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs9911578 1.000 rs1472288 chr17:56910720 G/A cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs57590327 0.503 rs13062741 chr3:81887124 C/T cg07356753 chr3:81810745 GBE1 -0.69 -6.34 -0.49 3.87e-9 Extraversion; TGCT cis rs7027203 0.576 rs7865043 chr9:96549004 G/T cg13679303 chr9:96623674 NA 0.54 7.68 0.57 4.04e-12 DNA methylation (variation); TGCT trans rs4650994 0.623 rs12121188 chr1:178622499 G/A cg05059571 chr16:84539110 KIAA1609 0.41 7.14 0.54 7.07e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs1395 0.778 rs60631624 chr2:27497815 T/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.62 8.02 0.58 6.76e-13 Blood metabolite levels; TGCT cis rs1799949 1.000 rs11649954 chr17:41420035 A/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT trans rs62103177 0.810 rs62096745 chr18:77619135 A/G cg05926928 chr17:57297772 GDPD1 1.22 11.16 0.71 1.85e-20 Opioid sensitivity; TGCT cis rs2832191 0.671 rs68101501 chr21:30513229 G/T cg24692254 chr21:30365293 RNF160 -0.61 -5.41 -0.44 3.08e-7 Dental caries; TGCT cis rs8141529 0.778 rs9625566 chr22:29162506 G/A cg02153584 chr22:29168773 CCDC117 0.7 6.15 0.48 9.93e-9 Lymphocyte counts; TGCT cis rs11190604 1.000 rs1417823 chr10:102227886 C/T cg23241863 chr10:102295624 HIF1AN -0.63 -4.97 -0.41 2.2e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9788333 0.792 rs34479949 chr13:21895574 G/A cg22663859 chr13:21900854 NA 0.33 4.6 0.38 1.03e-5 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs9486719 0.843 rs3849198 chr6:97036539 C/A cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs6921919 0.525 rs11760133 chr6:28386739 A/T cg18815343 chr6:28367644 ZSCAN12 -0.52 -5.01 -0.41 1.83e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4819852 0.752 rs917479 chr22:19973205 T/G cg07821417 chr22:19972146 ARVCF 0.19 4.56 0.38 1.2e-5 Pulse pressure; TGCT trans rs8073060 0.544 rs7211724 chr17:33993414 C/G cg19694781 chr19:47549865 TMEM160 -0.62 -14.07 -0.78 1.86e-27 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6570726 0.791 rs6900040 chr6:145893134 C/T cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs6429082 0.715 rs9793740 chr1:235595590 T/C cg26050004 chr1:235667680 B3GALNT2 -0.54 -4.77 -0.39 5.07e-6 Adiposity; TGCT cis rs6938 0.618 rs11638130 chr15:75183935 G/A cg10253484 chr15:75165896 SCAMP2 -0.6 -5.5 -0.44 2.06e-7 Breast cancer; TGCT cis rs7772486 0.875 rs2814875 chr6:146305810 G/A cg13319975 chr6:146136371 FBXO30 -0.52 -4.62 -0.38 9.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs916888 0.697 rs199516 chr17:44856485 C/T cg17911788 chr17:44343683 NA 0.62 6.56 0.51 1.32e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9388451 0.531 rs9321057 chr6:126156943 G/A cg05901451 chr6:126070800 HEY2 -0.74 -7.69 -0.57 3.97e-12 Brugada syndrome; TGCT cis rs1062177 1.000 rs2915878 chr5:151149662 A/G cg00977110 chr5:151150581 G3BP1 0.4 4.62 0.38 9.43e-6 Preschool internalizing problems; TGCT cis rs12579753 1.000 rs12827923 chr12:82242067 G/A cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs514406 0.505 rs427319 chr1:53178807 T/G cg24675658 chr1:53192096 ZYG11B -0.79 -9.71 -0.66 6.32e-17 Monocyte count; TGCT cis rs514406 0.825 rs28817407 chr1:53226116 G/A cg16325326 chr1:53192061 ZYG11B -0.71 -8.82 -0.62 8.9e-15 Monocyte count; TGCT cis rs1395 0.778 rs17005956 chr2:27451099 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.6 0.65 1.2e-16 Blood metabolite levels; TGCT trans rs12599106 0.648 rs12447240 chr16:34928236 C/T cg05064044 chr6:292385 DUSP22 0.65 6.87 0.53 2.8e-10 Menopause (age at onset); TGCT cis rs9486715 0.659 rs9399930 chr6:96854444 G/T cg18709589 chr6:96969512 KIAA0776 0.69 6.15 0.48 9.69e-9 Headache; TGCT cis rs7178572 0.962 rs12324627 chr15:77767539 A/G cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs4925386 0.681 rs2427294 chr20:60927257 G/A cg06026331 chr20:60912101 LAMA5 0.32 4.91 0.4 2.84e-6 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs6582630 0.537 rs8189533 chr12:38391068 A/G cg13010199 chr12:38710504 ALG10B 0.63 4.92 0.4 2.64e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs11718455 0.960 rs35277738 chr3:44006732 T/C cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs35146811 0.735 rs1138417 chr7:99807146 C/G cg13334819 chr7:99746414 C7orf59 0.74 6.62 0.51 9.79e-10 Coronary artery disease; TGCT cis rs9457247 1.000 rs408087 chr6:167398952 C/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs3087591 0.959 rs2940182 chr17:29410944 A/G cg24425628 chr17:29625626 OMG;NF1 0.46 6.94 0.53 1.93e-10 Hip circumference; TGCT cis rs669446 0.561 rs559575 chr1:44089940 A/G cg12908607 chr1:44402522 ARTN -0.54 -5.68 -0.45 8.9e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs1775715 0.737 rs2808028 chr10:32101189 G/A cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.38e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs748404 0.660 rs2602141 chr15:43724646 A/C cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.76 0.39 5.35e-6 Lung cancer; TGCT cis rs6563842 0.563 rs4941991 chr13:41335719 T/C cg21288729 chr13:41239152 FOXO1 0.88 7.87 0.58 1.49e-12 Eosinophil percentage of granulocytes;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs7178424 0.742 rs1981916 chr15:62171479 T/C cg00456672 chr15:62358751 C2CD4A -0.31 -4.72 -0.39 6.37e-6 Height; TGCT cis rs1030877 0.960 rs3792050 chr2:105902255 T/C cg02079111 chr2:105885981 TGFBRAP1 -0.17 -4.82 -0.4 4.19e-6 Obesity-related traits; TGCT cis rs2688608 0.967 rs2688609 chr10:75658181 A/G cg19442545 chr10:75533431 FUT11 0.29 4.62 0.38 9.62e-6 Inflammatory bowel disease; TGCT cis rs727505 1.000 rs17246404 chr7:124462661 C/T cg23710748 chr7:124431027 NA -0.26 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs1670533 1.000 rs3816474 chr4:1050653 G/A cg18657303 chr4:1051139 NA 0.32 4.9 0.4 2.9e-6 Recombination rate (females); TGCT cis rs4253772 0.637 rs3087501 chr22:46647909 A/G cg09491104 chr22:46646882 C22orf40 -0.61 -6.25 -0.49 6.14e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs10992471 0.528 rs10115290 chr9:95195858 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -5.12 -0.42 1.15e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs916888 0.647 rs199449 chr17:44808902 G/A cg01570182 chr17:44337453 NA 0.83 8.07 0.59 5.19e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8077889 0.917 rs28694735 chr17:41912144 A/G cg26893861 chr17:41843967 DUSP3 1.11 13.43 0.77 6.22e-26 Triglycerides; TGCT cis rs3806843 0.551 rs246018 chr5:140335043 T/C cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs78487399 0.710 rs7567685 chr2:43668169 G/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.72 4.62 0.38 9.53e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6714710 0.580 rs6711101 chr2:98379813 G/A cg26665480 chr2:98280029 ACTR1B 0.66 6.17 0.48 8.8e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg15687855 chr3:44754131 ZNF502 -0.43 -5.17 -0.42 9.22e-7 Depressive symptoms; TGCT cis rs9368481 0.761 rs4713062 chr6:26948195 A/G cg26531700 chr6:26746687 NA -0.58 -5.48 -0.44 2.31e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 0.954 rs903717 chr8:58167856 A/G cg21724239 chr8:58056113 NA 0.32 4.45 0.37 1.93e-5 Developmental language disorder (linguistic errors); TGCT cis rs7072216 0.763 rs2274244 chr10:100175218 A/G cg26618903 chr10:100175079 PYROXD2 -0.4 -4.49 -0.37 1.64e-5 Metabolite levels; TGCT cis rs9640161 0.830 rs3757425 chr7:150067640 A/C cg10018233 chr7:150070692 REPIN1 0.4 6.51 0.5 1.68e-9 Blood protein levels;Circulating chemerin levels; TGCT cis rs12908161 0.959 rs35557864 chr15:85331629 A/G cg12863693 chr15:85201151 NMB 0.42 4.95 0.41 2.38e-6 Schizophrenia; TGCT cis rs28595532 0.920 rs115294251 chr4:119772833 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs12950390 0.814 rs11659069 chr17:45834275 G/T cg06532163 chr17:45867833 NA 0.34 5.31 0.43 4.82e-7 IgG glycosylation; TGCT cis rs909674 0.818 rs7364148 chr22:39842165 T/C cg01416388 chr22:39784598 NA -0.69 -6.23 -0.49 6.78e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs4808199 0.948 rs2074300 chr19:19380996 G/T cg03709012 chr19:19516395 GATAD2A 0.8 6.14 0.48 1.03e-8 Nonalcoholic fatty liver disease; TGCT cis rs6951245 1.000 rs113575110 chr7:1084394 G/A cg26224354 chr7:1096374 C7orf50;GPR146 -0.33 -5.16 -0.42 9.32e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7647973 0.626 rs7637711 chr3:49829653 A/G cg03060546 chr3:49711283 APEH -0.63 -5.63 -0.45 1.12e-7 Menarche (age at onset); TGCT cis rs2996428 0.667 rs10492942 chr1:3764216 C/T cg17848003 chr1:3704513 LRRC47 0.19 5.21 0.42 7.56e-7 Red cell distribution width; TGCT cis rs6088580 0.634 rs6058073 chr20:33116483 T/C cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs1998418 0.551 rs60499622 chr10:126551228 C/T cg03585084 chr10:126284563 LHPP 0.28 4.76 0.39 5.39e-6 Mean platelet volume; TGCT cis rs11148252 0.904 rs7990581 chr13:53019433 A/G cg00495681 chr13:53174319 NA 0.59 6.1 0.48 1.24e-8 Lewy body disease; TGCT cis rs9400467 0.506 rs12192617 chr6:111490275 A/G cg15721981 chr6:111408429 SLC16A10 0.69 4.5 0.37 1.56e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs28595532 0.748 rs72670258 chr4:119391660 A/T cg21605333 chr4:119757512 SEC24D 0.82 5.41 0.44 3.15e-7 Cannabis dependence symptom count; TGCT cis rs13326165 0.715 rs34355561 chr3:52383120 G/A cg27565382 chr3:53032988 SFMBT1 0.36 4.8 0.4 4.54e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs6988636 1.000 rs58189203 chr8:124184739 G/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs939658 0.805 rs35602654 chr15:79417527 T/A cg17916960 chr15:79447300 NA -0.5 -7.7 -0.57 3.74e-12 Refractive error; TGCT cis rs13190036 1.000 rs71601343 chr5:176632107 G/A cg18465082 chr5:176734745 MXD3 0.32 4.46 0.37 1.78e-5 Neutrophil percentage of white cells;Lymphocyte percentage of white cells; TGCT cis rs2456568 0.778 rs7944194 chr11:93682413 C/G cg26875233 chr11:93583750 C11orf90 0.39 4.65 0.39 8.39e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7760949 0.963 rs1330118 chr6:13921016 C/T cg27413430 chr6:13925136 RNF182 -0.54 -4.9 -0.4 2.97e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs854765 0.616 rs8070624 chr17:17843396 G/A cg09796270 chr17:17721594 SREBF1 0.28 5.64 0.45 1.07e-7 Total body bone mineral density; TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg26338869 chr17:61819248 STRADA -0.5 -4.55 -0.38 1.24e-5 Prudent dietary pattern; TGCT cis rs798554 0.679 rs2533868 chr7:2886559 G/A cg13628971 chr7:2884303 GNA12 0.54 4.53 0.38 1.36e-5 Height; TGCT cis rs9916302 0.706 rs7212621 chr17:37527911 T/G cg07936489 chr17:37558343 FBXL20 0.87 6.26 0.49 5.63e-9 Glomerular filtration rate (creatinine); TGCT cis rs10510102 0.808 rs11200296 chr10:123731471 C/T cg23691251 chr10:123688108 ATE1 -0.67 -4.76 -0.39 5.23e-6 Breast cancer; TGCT trans rs916888 0.773 rs199439 chr17:44793503 A/G cg22433210 chr17:43662623 NA 1.06 7.29 0.55 3.2e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs644799 0.965 rs499076 chr11:95546341 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9653442 0.564 rs11687586 chr2:100789346 A/G cg07810366 chr2:100720526 AFF3 -0.35 -5.26 -0.43 6e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs13108904 0.870 rs4974577 chr4:1266046 G/A cg13342137 chr4:2252803 MXD4 0.17 4.55 0.38 1.27e-5 Obesity-related traits; TGCT trans rs8073060 0.586 rs117573546 chr17:33909588 G/A cg19694781 chr19:47549865 TMEM160 0.6 13.04 0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs67340775 0.541 rs200979 chr6:27852357 G/A cg26587870 chr6:27730563 NA -0.34 -4.62 -0.38 9.28e-6 Lung cancer in ever smokers; TGCT cis rs55882075 0.722 rs10903245 chr5:179133608 T/C cg14593053 chr5:179126677 CANX 0.47 5.28 0.43 5.7e-7 Monocyte percentage of white cells; TGCT cis rs7208859 0.623 rs2035494 chr17:29130393 T/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs7565124 0.955 rs67500069 chr2:20269864 A/C cg00462460 chr2:20212509 MATN3 -0.42 -4.64 -0.38 8.69e-6 Major depressive disorder; TGCT cis rs9611565 0.625 rs9611606 chr22:41931074 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs28386778 0.897 rs2727323 chr17:61921999 G/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs7752195 0.643 rs115949281 chr6:25240214 G/A cg16898833 chr6:26189333 HIST1H4D 1.17 5.47 0.44 2.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7909074 0.832 rs10793564 chr10:45386352 C/A cg04218760 chr10:45406644 TMEM72 -0.28 -5.59 -0.45 1.38e-7 Mean corpuscular volume; TGCT trans rs57221529 0.825 rs7443550 chr5:578404 G/T cg25482853 chr8:67687455 SGK3 1.16 10.5 0.69 7.91e-19 Lung disease severity in cystic fibrosis; TGCT cis rs5769765 1.000 rs5770742 chr22:50270309 T/C cg15316289 chr22:50310904 ALG12;CRELD2 -0.41 -6.13 -0.48 1.08e-8 Schizophrenia; TGCT cis rs35264875 0.796 rs72928657 chr11:68852336 T/C cg02660097 chr11:68866761 NA 0.32 4.96 0.41 2.3e-6 Blond vs. brown hair color; TGCT cis rs9911578 0.967 rs405684 chr17:56777148 T/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs6964587 0.692 rs17672805 chr7:91573466 A/G cg17063962 chr7:91808500 NA -0.76 -7.12 -0.54 7.65e-11 Breast cancer; TGCT cis rs79349575 0.811 rs12601072 chr17:46997998 T/C cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs12541335 0.536 rs4266653 chr8:22169087 A/G cg18135555 chr8:22132992 PIWIL2 0.28 5.8 0.46 5.25e-8 Hypertriglyceridemia; TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg16325326 chr1:53192061 ZYG11B 0.56 6.4 0.5 2.83e-9 Monocyte count; TGCT cis rs1375194 0.606 rs10188817 chr2:33815471 A/G cg04131969 chr2:33951647 MYADML -0.56 -4.84 -0.4 3.85e-6 Response to antidepressants in depression; TGCT cis rs2739330 0.828 rs5760107 chr22:24252597 T/C cg06753367 chr22:24256600 NA -0.24 -4.51 -0.38 1.5e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7917772 0.503 rs11191330 chr10:104306160 G/T cg05855489 chr10:104503620 C10orf26 -0.6 -5.26 -0.43 6.16e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6570726 0.902 rs973855 chr6:145781850 C/T cg23711669 chr6:146136114 FBXO30 -0.71 -6.74 -0.52 5.36e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs77741769 0.529 rs2893876 chr12:121245158 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs4819052 0.851 rs4818768 chr21:46659818 T/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.61 5.11 0.42 1.18e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9393777 0.513 rs13190754 chr6:26587406 G/A cg15659132 chr6:26577336 NA -0.64 -4.82 -0.4 4.09e-6 Intelligence (multi-trait analysis); TGCT cis rs13217239 0.646 rs12527111 chr6:27006475 C/T cg26531700 chr6:26746687 NA 0.68 6.86 0.52 2.83e-10 Schizophrenia; TGCT cis rs4654899 1.000 rs6703227 chr1:21374810 A/G cg01072550 chr1:21505969 NA -0.49 -7.88 -0.58 1.41e-12 Superior frontal gyrus grey matter volume; TGCT cis rs4455778 0.580 rs56191832 chr7:49128223 C/A cg26309511 chr7:48887640 NA 0.5 6.51 0.5 1.66e-9 Lung cancer in never smokers; TGCT cis rs9611565 0.765 rs132905 chr22:41799106 C/A cg17554472 chr22:41940697 POLR3H 0.43 4.79 0.39 4.73e-6 Vitiligo; TGCT trans rs4824093 0.610 rs12106611 chr22:50242686 G/A cg09872104 chr7:134855509 C7orf49 -0.91 -7.33 -0.55 2.66e-11 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs28595532 0.920 rs112016126 chr4:119726528 C/T cg21605333 chr4:119757512 SEC24D 1.72 8.96 0.63 3.99e-15 Cannabis dependence symptom count; TGCT cis rs6088580 0.634 rs6141471 chr20:33006730 A/G cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs78456975 0.506 rs6756310 chr2:1549809 A/G cg12573674 chr2:1569213 NA -0.49 -4.95 -0.41 2.41e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs68170813 0.605 rs4730227 chr7:106904031 G/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs7772486 0.754 rs6570718 chr6:146088443 T/G cg13319975 chr6:146136371 FBXO30 0.58 5.29 0.43 5.27e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7746199 0.736 rs6904596 chr6:27491299 G/A cg08798685 chr6:27730294 NA -0.37 -4.67 -0.39 7.76e-6 Gait speed in old age;Autism spectrum disorder or schizophrenia; TGCT cis rs7647973 0.593 rs7652179 chr3:49808618 T/A cg03060546 chr3:49711283 APEH -0.61 -5.14 -0.42 1.04e-6 Menarche (age at onset); TGCT cis rs12510870 0.729 rs10938077 chr4:74375374 A/G cg05868023 chr4:75230803 EREG 0.56 5.05 0.41 1.56e-6 Iris color (b* coordinate); TGCT cis rs78456975 0.506 rs13384333 chr2:1555531 A/C cg12573674 chr2:1569213 NA -0.44 -4.71 -0.39 6.64e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs9611565 0.649 rs202625 chr22:41827082 G/A cg13695892 chr22:41940480 POLR3H 0.93 9.1 0.63 1.88e-15 Vitiligo; TGCT cis rs7552404 0.731 rs11588578 chr1:76400539 T/G cg22875332 chr1:76189707 ACADM 0.66 6.4 0.5 2.94e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs950169 0.922 rs8037078 chr15:84818871 A/G cg12863693 chr15:85201151 NMB -0.41 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT trans rs7618501 1.000 rs2247036 chr3:49882349 C/T cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.19 0.76 2.31e-25 Intelligence (multi-trait analysis); TGCT cis rs11098499 0.866 rs12501602 chr4:120287935 A/T cg09307838 chr4:120376055 NA 0.58 5.77 0.46 5.97e-8 Corneal astigmatism; TGCT cis rs7769051 0.522 rs11965927 chr6:133101353 T/C cg22852734 chr6:133119734 C6orf192 1.16 4.48 0.37 1.67e-5 Type 2 diabetes nephropathy; TGCT cis rs919433 0.679 rs1902249 chr2:198521356 T/C cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs2120019 0.938 rs2304903 chr15:75315778 A/G cg17294928 chr15:75287854 SCAMP5 -0.79 -6.27 -0.49 5.46e-9 Blood trace element (Zn levels); TGCT cis rs9467711 0.606 rs2072806 chr6:26385093 C/G cg10795676 chr6:26370623 BTN3A2 -0.48 -4.78 -0.39 4.78e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs797680 0.964 rs12038699 chr1:93558818 A/G cg17826107 chr1:92977322 EVI5 -0.22 -5.11 -0.42 1.19e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs854765 0.647 rs854791 chr17:18029857 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.7 6.99 0.53 1.52e-10 Total body bone mineral density; TGCT cis rs611744 0.967 rs639059 chr8:109236119 G/A cg21045802 chr8:109455806 TTC35 0.52 4.69 0.39 6.99e-6 Dupuytren's disease; TGCT cis rs10504229 0.906 rs17805439 chr8:58172400 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2180341 0.960 rs9375503 chr6:127677071 T/C cg24812749 chr6:127587940 RNF146 1.01 7.62 0.56 5.59e-12 Breast cancer; TGCT cis rs11578119 0.933 rs12140770 chr1:170449235 T/A cg09767346 chr1:170501363 GORAB 0.73 5.8 0.46 5.23e-8 Male-pattern baldness; TGCT cis rs896854 0.625 rs13281709 chr8:95972819 T/A cg23172400 chr8:95962367 TP53INP1 -0.39 -6.52 -0.51 1.57e-9 Type 2 diabetes; TGCT cis rs7586879 1.000 rs10175064 chr2:25117537 T/C cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs7666738 0.519 rs28539191 chr4:98821552 C/T cg05340658 chr4:99064831 C4orf37 0.55 5.96 0.47 2.42e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs10804591 1.000 rs2811435 chr3:129339470 C/T cg07730360 chr3:128845626 NA -0.2 -4.66 -0.39 7.91e-6 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2688608 0.901 rs2664280 chr10:75617344 A/T cg19442545 chr10:75533431 FUT11 0.32 5.07 0.41 1.42e-6 Inflammatory bowel disease; TGCT cis rs7568458 0.870 rs1562323 chr2:85809711 T/C cg17127132 chr2:85788382 GGCX 0.71 6.51 0.5 1.65e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs7267979 0.932 rs433352 chr20:25467992 C/T cg03522245 chr20:25566470 NINL -0.61 -6.59 -0.51 1.15e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7567389 0.600 rs11691088 chr2:128131853 A/G cg09760422 chr2:128146352 NA 0.39 5.18 0.42 8.76e-7 Self-rated health; TGCT cis rs6088580 0.634 rs4277599 chr20:33008905 A/G cg08999081 chr20:33150536 PIGU -0.29 -5.73 -0.46 7.34e-8 Glomerular filtration rate (creatinine); TGCT cis rs2688608 0.592 rs10824032 chr10:75528130 G/A cg04320760 chr10:75533139 FUT11 -0.38 -5.9 -0.47 3.24e-8 Inflammatory bowel disease; TGCT cis rs1113500 0.541 rs6692571 chr1:108576684 G/A cg06207961 chr1:108661230 NA 0.24 4.7 0.39 6.91e-6 Growth-regulated protein alpha levels; TGCT cis rs2153535 0.563 rs1737584 chr6:8536742 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.67 0.45 9.45e-8 Motion sickness; TGCT cis rs9467773 1.000 rs3736781 chr6:26505362 G/A cg15659132 chr6:26577336 NA 0.86 12.18 0.74 6.14e-23 Intelligence (multi-trait analysis); TGCT trans rs77457752 0.690 rs12352669 chr9:13911919 A/T cg23609682 chr1:3070786 PRDM16 -0.45 -6.64 -0.51 8.66e-10 Breast cancer; TGCT cis rs67072384 0.901 rs67288233 chr11:72458361 G/A cg03713592 chr11:72463424 ARAP1 -0.93 -4.66 -0.39 7.89e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs9467711 0.606 rs9393715 chr6:26375645 G/A cg16898833 chr6:26189333 HIST1H4D 1.1 5.3 0.43 5.16e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1153858 0.723 rs1719238 chr15:45594766 C/T cg26924012 chr15:45694286 SPATA5L1 -1.01 -11.05 -0.7 3.45e-20 Homoarginine levels; TGCT cis rs1799949 1.000 rs4793194 chr17:41218333 G/A cg05368731 chr17:41323189 NBR1 1.19 13.98 0.78 2.93e-27 Menopause (age at onset); TGCT cis rs2033711 0.870 rs4801270 chr19:58932762 C/A cg04608855 chr19:58913158 NA 0.57 5.7 0.46 8.44e-8 Uric acid clearance; TGCT cis rs933688 1.000 rs35712350 chr5:90679519 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 10.13 0.67 6.16e-18 Smoking behavior; TGCT cis rs7909074 1.000 rs4948925 chr10:45392455 C/T cg05187965 chr10:45406764 TMEM72 -0.24 -5.28 -0.43 5.7e-7 Mean corpuscular volume; TGCT cis rs7474896 0.561 rs2474603 chr10:38445682 C/T cg25427524 chr10:38739819 LOC399744 -0.35 -4.55 -0.38 1.24e-5 Obesity (extreme); TGCT cis rs7959452 0.532 rs2291005 chr12:69764388 A/G cg20891283 chr12:69753455 YEATS4 0.83 8.61 0.61 2.8e-14 Blood protein levels; TGCT cis rs7772486 0.597 rs1970306 chr6:146154543 A/G cg23711669 chr6:146136114 FBXO30 0.76 7.12 0.54 7.61e-11 Lobe attachment (rater-scored or self-reported); TGCT cis rs4242434 0.889 rs4592028 chr8:22449484 T/C cg03733263 chr8:22462867 KIAA1967 1.15 18.4 0.86 2.98e-37 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs4900538 0.855 rs762105 chr14:102830175 A/G cg18135206 chr14:102964638 TECPR2 -0.2 -4.55 -0.38 1.28e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6089584 0.816 rs744778 chr20:60631365 A/G cg13770153 chr20:60521292 NA -0.6 -7.89 -0.58 1.37e-12 Body mass index; TGCT cis rs2204008 0.715 rs11525003 chr12:38332359 G/A cg13010199 chr12:38710504 ALG10B 0.58 4.55 0.38 1.26e-5 Bladder cancer; TGCT cis rs7666738 0.830 rs1426665 chr4:99027764 C/T cg05340658 chr4:99064831 C4orf37 0.51 5.82 0.46 4.75e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs3741404 0.560 rs2875748 chr11:63915537 G/A cg19465662 chr11:63993652 NUDT22;TRPT1 -0.77 -7.46 -0.56 1.34e-11 Platelet count; TGCT cis rs763121 0.853 rs6001182 chr22:39047443 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs7959452 0.558 rs1478464 chr12:69779789 G/C cg14784868 chr12:69753453 YEATS4 0.84 8.95 0.63 4.25e-15 Blood protein levels; TGCT cis rs4689592 0.503 rs11945642 chr4:7051065 G/C cg26116260 chr4:7069785 GRPEL1 -1.02 -8.21 -0.59 2.41e-13 Monocyte percentage of white cells; TGCT cis rs7917772 0.503 rs11191325 chr10:104302933 G/A cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4788570 0.655 rs7359478 chr16:71825445 A/G cg06353428 chr16:71660113 MARVELD3 1.53 12.59 0.75 6.48e-24 Intelligence (multi-trait analysis); TGCT cis rs12701220 0.894 rs12701348 chr7:1039457 C/T cg27454412 chr7:1067447 C7orf50 -0.46 -4.44 -0.37 1.95e-5 Bronchopulmonary dysplasia; TGCT cis rs9910055 0.529 rs228764 chr17:42185469 A/G cg19774624 chr17:42201019 HDAC5 0.75 7.12 0.54 7.85e-11 Total body bone mineral density; TGCT cis rs9467773 0.620 rs2504567 chr6:26662920 C/G cg02458000 chr6:26745757 NA 0.51 4.66 0.39 8.19e-6 Intelligence (multi-trait analysis); TGCT cis rs2836974 0.897 rs2836944 chr21:40593539 G/A cg11890956 chr21:40555474 PSMG1 1.1 12.31 0.74 2.99e-23 Cognitive function; TGCT cis rs2658782 1.000 rs2019814 chr11:93168885 A/G cg15737290 chr11:93063684 CCDC67 0.79 5.61 0.45 1.24e-7 Pulmonary function decline; TGCT cis rs2692947 0.795 rs2252697 chr2:96778190 G/C cg05933789 chr2:97190408 NA -0.16 -4.78 -0.39 4.79e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs1997103 1.000 rs6953494 chr7:55412157 G/A cg17469321 chr7:55412551 NA 0.65 6.75 0.52 5.08e-10 QRS interval (sulfonylurea treatment interaction); TGCT cis rs11031096 0.655 rs12275634 chr11:4211754 T/G cg18678763 chr11:4115507 RRM1 -0.45 -5.77 -0.46 6.11e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs5750830 0.649 rs5757664 chr22:39821536 A/G cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs514406 0.621 rs1930306 chr1:53195686 C/G cg01802117 chr1:53393560 SCP2 0.42 4.92 0.4 2.69e-6 Monocyte count; TGCT cis rs8062405 0.573 rs7187575 chr16:28990101 C/T cg01117621 chr16:28073818 GSG1L -0.37 -4.73 -0.39 6.13e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs769267 0.930 rs2304098 chr19:19646272 T/C cg03709012 chr19:19516395 GATAD2A 0.74 6.07 0.48 1.44e-8 Tonsillectomy; TGCT cis rs2153535 0.580 rs9328478 chr6:8519183 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs7772486 0.686 rs1337841 chr6:146059487 A/G cg13319975 chr6:146136371 FBXO30 0.52 4.73 0.39 6.06e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs700651 0.789 rs1813106 chr2:198880589 A/G cg00792783 chr2:198669748 PLCL1 0.59 5.34 0.43 4.33e-7 Intracranial aneurysm; TGCT cis rs2301573 1.000 rs2301573 chr3:129305919 A/G cg12216435 chr3:128995479 COPG 0.38 4.66 0.39 7.98e-6 Hip circumference; TGCT cis rs10504229 0.871 rs10504227 chr8:58162005 G/A cg08280861 chr8:58055591 NA 0.35 4.72 0.39 6.16e-6 Developmental language disorder (linguistic errors); TGCT cis rs875971 1.000 rs1183245 chr7:65541185 C/T cg11764359 chr7:65958608 NA -0.56 -4.7 -0.39 6.74e-6 Aortic root size; TGCT cis rs7940866 0.803 rs1865296 chr11:130882944 C/T cg12179176 chr11:130786555 SNX19 -0.6 -5.82 -0.46 4.67e-8 Schizophrenia; TGCT cis rs908922 0.676 rs945789 chr1:152512705 C/A cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs727563 0.638 rs5996058 chr22:42141452 A/G cg17554472 chr22:41940697 POLR3H 0.48 5.02 0.41 1.73e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs10479542 0.806 rs4700836 chr5:178976393 A/G cg09060608 chr5:178986726 RUFY1 0.47 5.25 0.43 6.34e-7 Lung cancer; TGCT cis rs1799949 1.000 rs8176202 chr17:41230228 G/A cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.9e-26 Menopause (age at onset); TGCT cis rs6598955 0.671 rs17162105 chr1:26591255 A/G cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT trans rs66573146 0.831 rs56300156 chr4:6990813 G/C cg07817883 chr1:32538562 TMEM39B 1.32 6.94 0.53 1.92e-10 Granulocyte percentage of myeloid white cells; TGCT cis rs1552244 0.882 rs2130813 chr3:10038706 A/C cg00149659 chr3:10157352 C3orf10 0.78 4.99 0.41 2.04e-6 Alzheimer's disease; TGCT cis rs9640161 0.789 rs10282458 chr7:150045302 C/T cg17279839 chr7:150038598 RARRES2 0.43 4.64 0.38 8.89e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs514406 0.679 rs541852 chr1:53256834 A/G cg27535305 chr1:53392650 SCP2 0.26 5.09 0.42 1.28e-6 Monocyte count; TGCT cis rs769267 0.930 rs751856 chr19:19602945 A/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs367943 1.000 rs348960 chr5:112820651 C/A cg12552261 chr5:112820674 MCC 0.24 4.91 0.4 2.81e-6 Type 2 diabetes; TGCT cis rs74233809 1.000 rs77787671 chr10:104776205 C/T cg05855489 chr10:104503620 C10orf26 0.76 4.53 0.38 1.36e-5 Birth weight; TGCT cis rs76419734 0.614 rs17035936 chr4:106525864 T/G cg24545054 chr4:106630052 GSTCD;INTS12 0.82 4.66 0.39 7.91e-6 Post bronchodilator FEV1; TGCT cis rs7246967 0.611 rs12978511 chr19:22819216 C/T cg05241461 chr19:22816980 ZNF492 0.71 4.79 0.4 4.6e-6 Bronchopulmonary dysplasia; TGCT cis rs7659604 1.000 rs6846232 chr4:122664805 A/G cg19748678 chr4:122722346 EXOSC9 0.57 5.5 0.44 2.07e-7 Type 2 diabetes; TGCT cis rs3617 0.652 rs7630552 chr3:52891570 G/C cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.79 0.4 4.67e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs2295359 0.892 rs4655687 chr1:67649946 C/T cg12940439 chr1:67600707 NA 0.6 6.28 0.49 5.25e-9 Psoriasis; TGCT cis rs892961 0.932 rs2170863 chr17:75415037 C/T cg05865280 chr17:75406074 SEPT9 0.29 6.98 0.53 1.61e-10 Airflow obstruction; TGCT cis rs17767294 0.708 rs72851139 chr6:28042698 G/T cg08851530 chr6:28072375 NA 1.56 7.21 0.54 4.9e-11 Parkinson's disease; TGCT cis rs769267 1.000 rs2074090 chr19:19449686 G/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.72 -6.47 -0.5 2.04e-9 Tonsillectomy; TGCT cis rs7786808 0.552 rs35809824 chr7:158185067 C/T cg01191920 chr7:158217561 PTPRN2 -0.36 -5.36 -0.43 3.86e-7 Obesity-related traits; TGCT cis rs782590 0.837 rs782573 chr2:55912961 T/C cg03859395 chr2:55845619 SMEK2 0.81 9.36 0.64 4.35e-16 Metabolic syndrome; TGCT trans rs2688608 0.592 rs7909544 chr10:75484004 G/C cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs11118844 0.843 rs12144586 chr1:221919378 A/G cg04222084 chr1:221915650 DUSP10 -0.78 -5.42 -0.44 2.99e-7 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs6547741 0.816 rs10201652 chr2:27874332 A/C cg27432699 chr2:27873401 GPN1 -0.24 -6.14 -0.48 1.04e-8 Oral cavity cancer; TGCT trans rs797680 0.856 rs7512911 chr1:93715818 C/G cg27528825 chr2:159282178 CCDC148 0.35 6.88 0.53 2.65e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7666738 0.830 rs13125432 chr4:98961253 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.56 0.56 7.89e-12 Colonoscopy-negative controls vs population controls; TGCT trans rs12599106 0.680 rs34728702 chr16:34896584 A/G cg05064044 chr6:292385 DUSP22 -0.71 -7.27 -0.55 3.45e-11 Menopause (age at onset); TGCT cis rs66887589 0.592 rs28580295 chr4:120278873 C/T cg09307838 chr4:120376055 NA 0.46 4.59 0.38 1.09e-5 Diastolic blood pressure; TGCT cis rs3857536 0.605 rs36040831 chr6:66876588 G/A cg07460842 chr6:66804631 NA -0.52 -4.49 -0.37 1.6e-5 Blood trace element (Cu levels); TGCT cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs35883536 0.967 rs9434126 chr1:101106981 A/G cg06223162 chr1:101003688 GPR88 -0.29 -4.86 -0.4 3.53e-6 Monocyte count; TGCT cis rs7223966 1.000 rs8066719 chr17:61825764 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs13336428 0.730 rs3946124 chr16:1525779 A/G cg26690334 chr16:1524521 CLCN7 0.39 6.93 0.53 2.03e-10 Bone mineral density; TGCT cis rs35934224 0.783 rs34545894 chr22:19857942 C/G cg11182965 chr22:19864308 TXNRD2 -0.36 -5.02 -0.41 1.73e-6 Glaucoma (primary open-angle); TGCT trans rs459571 0.876 rs2520095 chr9:136919568 A/G cg09836344 chr4:1243392 C4orf42;CTBP1 -0.79 -8.59 -0.61 3.1e-14 Platelet distribution width; TGCT cis rs42648 0.837 rs3761804 chr7:89915338 C/T cg25739043 chr7:89950458 NA -0.59 -5.73 -0.46 7.21e-8 Homocysteine levels; TGCT cis rs1215050 0.791 rs165254 chr4:98763564 C/T cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7949030 0.765 rs11553576 chr11:62378801 T/C cg22862634 chr11:62369728 EML3;MTA2 0.69 8.69 0.62 1.83e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7264396 0.747 rs73283043 chr20:34383863 G/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.25 -0.43 6.36e-7 Total cholesterol levels; TGCT cis rs11190604 1.000 rs2295780 chr10:102305965 A/G cg23241863 chr10:102295624 HIF1AN 0.67 4.88 0.4 3.22e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10089 1.000 rs1842006 chr5:127508687 G/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.85 8.27 0.6 1.8e-13 Ileal carcinoids; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg11494091 chr17:61959527 GH2 0.61 14.81 0.8 3.37e-29 Prudent dietary pattern; TGCT cis rs12497850 0.864 rs6779394 chr3:49157771 G/A cg18654377 chr3:49208889 KLHDC8B -0.38 -4.78 -0.39 4.92e-6 Parkinson's disease; TGCT cis rs899997 0.954 rs11856441 chr15:79030526 T/G cg04896959 chr15:78267971 NA 0.35 5.11 0.42 1.18e-6 Coronary artery disease or large artery stroke; TGCT cis rs7647973 0.961 rs62259943 chr3:49425167 A/G cg06212747 chr3:49208901 KLHDC8B -0.59 -4.62 -0.38 9.36e-6 Menarche (age at onset); TGCT cis rs9916302 0.904 rs4239222 chr17:37696235 A/C cg07936489 chr17:37558343 FBXL20 0.63 4.85 0.4 3.67e-6 Glomerular filtration rate (creatinine); TGCT cis rs6866344 0.570 rs1132336 chr5:178140090 C/T cg10224037 chr5:178157518 ZNF354A 0.98 9.87 0.66 2.66e-17 Neutrophil percentage of white cells; TGCT cis rs6684514 1.000 rs12038217 chr1:156248297 C/T cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs7552404 0.690 rs11161620 chr1:76255228 A/G cg22875332 chr1:76189707 ACADM -0.63 -6.81 -0.52 3.72e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6845621 0.727 rs10032307 chr4:18911775 T/C cg12196642 chr4:18937545 NA -0.25 -4.48 -0.37 1.69e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs317689 0.876 rs547332 chr12:69743639 C/G cg11871910 chr12:69753446 YEATS4 0.59 5.19 0.42 8.46e-7 Response to diuretic therapy; TGCT cis rs2153535 0.580 rs915351 chr6:8442793 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs35146811 0.735 rs1727140 chr7:99815399 T/A cg04778012 chr7:99775508 STAG3;GPC2 -0.35 -4.93 -0.41 2.55e-6 Coronary artery disease; TGCT cis rs9435341 0.965 rs1730859 chr1:107617707 A/G cg09367891 chr1:107599246 PRMT6 0.61 5.21 0.42 7.69e-7 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs4819052 0.851 rs2838867 chr21:46713092 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.76 6.73 0.52 5.66e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9952991 0.566 rs534911 chr18:12857335 G/A cg23598886 chr18:12777645 NA 0.55 4.77 0.39 5.06e-6 Inflammatory skin disease; TGCT cis rs514406 0.505 rs7543239 chr1:53162416 A/G cg25767906 chr1:53392781 SCP2 -0.45 -4.85 -0.4 3.64e-6 Monocyte count; TGCT cis rs11971779 0.590 rs59602547 chr7:139117023 G/A cg07862535 chr7:139043722 LUC7L2 0.66 5.07 0.41 1.42e-6 Diisocyanate-induced asthma; TGCT cis rs7615952 0.932 rs9841157 chr3:125635655 C/A cg05084668 chr3:125655381 ALG1L -0.63 -4.49 -0.37 1.58e-5 Blood pressure (smoking interaction); TGCT cis rs28493229 0.881 rs73931345 chr19:41180347 G/A cg11601297 chr19:41224147 ITPKC;ADCK4 0.59 5.69 0.46 8.61e-8 Kawasaki disease; TGCT cis rs16854884 0.739 rs56196484 chr3:143786160 G/T cg06585982 chr3:143692056 C3orf58 0.59 4.74 0.39 5.84e-6 Economic and political preferences (feminism/equality); TGCT cis rs651907 0.535 rs35810977 chr3:101531380 G/A cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 10.47 0.68 9.31e-19 Colorectal cancer; TGCT cis rs6448317 0.906 rs4053966 chr4:24901466 A/G cg21108841 chr4:24914750 CCDC149 -0.66 -5.52 -0.44 1.89e-7 Heschl's gyrus morphology; TGCT cis rs7267979 0.932 rs446649 chr20:25467359 A/G cg14121845 chr20:25566513 NINL 0.51 5.7 0.46 8.26e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1499614 1.000 rs2707830 chr7:66167645 T/C cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs986417 0.901 rs7159628 chr14:61010688 A/C cg27398547 chr14:60952738 C14orf39 1.42 8.85 0.62 7.44e-15 Gut microbiota (bacterial taxa); TGCT cis rs56399783 0.901 rs11764225 chr7:2775607 G/A cg19731401 chr7:2775893 GNA12 0.35 4.97 0.41 2.18e-6 Childhood ear infection; TGCT cis rs2841277 0.708 rs10083374 chr14:105402994 T/C cg21017887 chr14:105400489 NA 0.38 5.42 0.44 3.03e-7 Rheumatoid arthritis; TGCT cis rs910316 0.836 rs6574212 chr14:75671659 G/A cg11812906 chr14:75593930 NEK9 -0.63 -6.15 -0.48 9.66e-9 Height; TGCT cis rs9467773 1.000 rs6940053 chr6:26562122 C/T cg09904177 chr6:26538194 HMGN4 0.66 6.6 0.51 1.05e-9 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.882 rs6796419 chr3:10040812 G/A cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT trans rs57221529 0.709 rs72703034 chr5:577101 C/T cg11887960 chr12:57824829 NA 1.1 9.44 0.65 2.89e-16 Lung disease severity in cystic fibrosis; TGCT cis rs941764 0.830 rs6575189 chr14:91840267 C/T cg10511902 chr14:91842949 CCDC88C 0.29 4.47 0.37 1.76e-5 Breast cancer; TGCT cis rs9549260 0.753 rs61963266 chr13:41171036 G/A cg21288729 chr13:41239152 FOXO1 0.67 4.68 0.39 7.31e-6 Red blood cell count; TGCT cis rs7312933 0.703 rs10880259 chr12:42558003 T/C cg11827402 chr12:42719852 PPHLN1;ZCRB1 0.55 5.06 0.41 1.45e-6 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9611565 0.694 rs5758365 chr22:41858657 A/G cg06634786 chr22:41940651 POLR3H 0.87 8.25 0.6 1.92e-13 Vitiligo; TGCT cis rs8031584 0.723 rs711224 chr15:31127921 G/C cg14829155 chr15:31115871 NA 0.37 4.86 0.4 3.43e-6 Huntington's disease progression; TGCT cis rs453301 0.658 rs9329175 chr8:8866661 C/T cg00184457 chr8:8946301 NA -0.25 -4.67 -0.39 7.61e-6 Joint mobility (Beighton score); TGCT trans rs6762477 0.748 rs11711407 chr3:50225029 A/G cg21659725 chr3:3221576 CRBN -0.66 -7.62 -0.56 5.68e-12 Menarche (age at onset); TGCT cis rs5769765 0.862 rs9616384 chr22:50313082 C/T cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.97 -0.76 7.81e-25 Schizophrenia; TGCT cis rs2970818 0.831 rs2907499 chr12:4616901 G/T cg02722637 chr12:4922070 KCNA6 -0.32 -4.59 -0.38 1.05e-5 Phosphorus levels; TGCT cis rs9372498 0.536 rs72952733 chr6:118834452 A/G cg21191810 chr6:118973309 C6orf204 -0.37 -4.8 -0.4 4.4e-6 Diastolic blood pressure; TGCT cis rs28386778 0.863 rs2584637 chr17:61942952 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs2228479 0.557 rs2293584 chr16:89888686 C/G cg06558623 chr16:89946397 TCF25 0.55 4.79 0.4 4.69e-6 Skin colour saturation; TGCT cis rs7432375 1.000 rs6439649 chr3:136371691 G/T cg12473912 chr3:136751656 NA -0.34 -4.93 -0.41 2.55e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs11792861 0.816 rs17792434 chr9:111667319 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.52 4.95 0.41 2.4e-6 Menarche (age at onset); TGCT cis rs875971 1.000 rs4717292 chr7:65895598 G/A cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs6594499 0.564 rs12518884 chr5:110452223 A/G cg04022379 chr5:110408740 TSLP 0.6 6.19 0.49 8.11e-9 Allergic disease (asthma, hay fever or eczema); TGCT cis rs78487399 0.808 rs7570242 chr2:43706002 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.56 -0.45 1.57e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs4925325 1.000 rs4925325 chr20:60514224 G/A cg23262073 chr20:60523788 NA 0.35 5.54 0.45 1.75e-7 Obesity-related traits; TGCT cis rs7681440 0.647 rs1372508 chr4:90819786 C/G cg10208370 chr4:90758469 SNCA 0.58 5.58 0.45 1.45e-7 Dementia with Lewy bodies; TGCT cis rs2729354 0.817 rs2649667 chr11:57270509 A/C cg24343310 chr11:57249947 NA 0.28 4.6 0.38 1.03e-5 Blood protein levels; TGCT cis rs9325144 0.600 rs1825807 chr12:38737007 T/C cg26384229 chr12:38710491 ALG10B 0.62 5.66 0.45 1e-7 Morning vs. evening chronotype; TGCT cis rs9443645 0.901 rs1027813 chr6:79552118 G/T cg05283184 chr6:79620031 NA 0.2 4.67 0.39 7.71e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.679 rs1596142 chr8:58032406 G/A cg08280861 chr8:58055591 NA 0.35 5.07 0.41 1.43e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs1120708 chr4:98931260 G/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2243480 1.000 rs458291 chr7:65520479 C/A cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs10791097 0.967 rs6590512 chr11:130717916 A/G cg05962950 chr11:130786565 SNX19 -0.7 -7.23 -0.54 4.26e-11 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs10504229 0.906 rs59336968 chr8:58176857 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7904368 0.951 rs7074647 chr10:16855455 T/C cg14835575 chr10:16859367 RSU1 0.63 6.53 0.51 1.49e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs17387100 0.901 rs73230220 chr4:15982382 G/A cg13480465 chr4:16795757 LDB2 -0.44 -5.08 -0.42 1.35e-6 Suicide attempts in depression or bipolar disorder; TGCT cis rs477895 0.713 rs11607165 chr11:63963947 T/G cg04317338 chr11:64019027 PLCB3 0.79 6.5 0.5 1.77e-9 Mean platelet volume; TGCT cis rs3935685 0.874 rs35028279 chr15:78003542 T/C cg03457338 chr15:78040120 NA -0.22 -5.59 -0.45 1.35e-7 Intelligence (multi-trait analysis); TGCT cis rs826838 0.651 rs1843896 chr12:38612913 G/C cg26384229 chr12:38710491 ALG10B 0.65 6.07 0.48 1.44e-8 Heart rate; TGCT cis rs2692947 0.740 rs4907280 chr2:96402126 A/G cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs2115630 1.000 rs7183401 chr15:85371944 G/T cg17173187 chr15:85201210 NMB -0.38 -4.62 -0.38 9.33e-6 P wave terminal force; TGCT cis rs9916302 0.904 rs801419 chr17:37466327 A/G cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs4711350 0.862 rs570749 chr6:33710229 C/T cg00334056 chr6:33755658 LEMD2 0.31 4.81 0.4 4.31e-6 Schizophrenia; TGCT cis rs2070433 0.706 rs3788265 chr21:47833789 G/T cg12379764 chr21:47803548 PCNT 0.63 5.32 0.43 4.64e-7 Lymphocyte counts; TGCT cis rs10504229 0.728 rs17804666 chr8:58154473 C/T cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs6088590 1.000 rs6088595 chr20:33358499 T/A cg24642439 chr20:33292090 TP53INP2 0.68 6.02 0.48 1.83e-8 Coronary artery disease; TGCT cis rs2013441 1.000 rs2703821 chr17:20121526 C/T cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs7833790 0.724 rs12676336 chr8:82771008 C/T cg23324259 chr8:82754387 SNX16 0.62 4.71 0.39 6.47e-6 Diastolic blood pressure; TGCT cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg27286337 chr10:134555280 INPP5A 0.45 5.32 0.43 4.64e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs12643440 0.538 rs1522080 chr4:17135354 G/C cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT trans rs1864982 0.685 rs1368379 chr5:146213535 A/C cg07017998 chr4:733617 PCGF3 0.28 6.88 0.53 2.68e-10 Alcohol dependence; TGCT cis rs12477438 0.501 rs17759607 chr2:99737005 T/C cg26064155 chr2:99771622 LIPT1;TSGA10 0.91 10.3 0.68 2.42e-18 Chronic sinus infection; TGCT cis rs2073300 1.000 rs6106669 chr20:23460328 C/T cg09953122 chr20:23471693 CST8 -0.66 -4.67 -0.39 7.68e-6 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs7729723 0.591 rs6890204 chr5:137818178 T/C cg19169342 chr5:137827400 NA 0.35 4.99 0.41 1.97e-6 Amyotrophic lateral sclerosis (C9orf72 mutation interaction); TGCT cis rs7017914 0.846 rs6472561 chr8:71955183 A/T cg23757474 chr8:71581111 LACTB2;XKR9 0.55 5.11 0.42 1.17e-6 Bone mineral density; TGCT cis rs877282 0.853 rs12779017 chr10:763619 T/C cg17470449 chr10:769945 NA 0.37 5.59 0.45 1.37e-7 Uric acid levels; TGCT cis rs62244186 0.659 rs62251383 chr3:44552421 A/G cg17546649 chr3:44802566 KIF15;KIAA1143 -0.37 -4.44 -0.37 1.99e-5 Depressive symptoms; TGCT cis rs79976124 0.719 rs34488909 chr6:66637850 T/C cg07460842 chr6:66804631 NA 0.58 5.12 0.42 1.14e-6 Type 2 diabetes; TGCT cis rs7917772 0.582 rs7907760 chr10:104345197 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7267979 1.000 rs6037121 chr20:25428311 G/A cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7666738 0.830 rs6818045 chr4:99049374 G/A cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7226408 0.857 rs11665258 chr18:34508112 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.8 0.4 4.39e-6 Obesity-related traits; TGCT cis rs35000415 0.938 rs17424602 chr7:128687940 A/G cg06242719 chr7:129414860 MIR183;MIR96 -0.32 -4.46 -0.37 1.83e-5 Systemic lupus erythematosus; TGCT trans rs2727020 0.635 rs7124266 chr11:49280857 T/G cg15704280 chr7:45808275 SEPT13 0.73 8.06 0.59 5.51e-13 Coronary artery disease; TGCT cis rs7772486 0.597 rs7746618 chr6:146281367 T/C cg05347473 chr6:146136440 FBXO30 -0.65 -6.15 -0.48 9.86e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs7010267 0.596 rs1905777 chr8:120021840 A/T cg17171407 chr8:119960777 TNFRSF11B 0.25 4.45 0.37 1.87e-5 Total body bone mineral density (age 45-60); TGCT cis rs986417 0.748 rs10147346 chr14:61083334 G/C cg27398547 chr14:60952738 C14orf39 1.33 9.79 0.66 4e-17 Gut microbiota (bacterial taxa); TGCT trans rs62103177 0.810 rs62103195 chr18:77629693 T/C cg05926928 chr17:57297772 GDPD1 1.21 10.83 0.7 1.23e-19 Opioid sensitivity; TGCT cis rs3796619 0.503 rs1466216 chr4:1071907 C/T cg27284194 chr4:1044797 NA -0.71 -8.06 -0.59 5.44e-13 Recombination rate (males); TGCT cis rs860295 0.529 rs17385065 chr1:155976388 A/G cg05700447 chr1:155978627 NA -0.19 -4.75 -0.39 5.57e-6 Body mass index; TGCT cis rs751728 1.000 rs3793079 chr6:33767788 T/A cg13859433 chr6:33739653 LEMD2 -0.39 -7.23 -0.54 4.25e-11 Crohn's disease; TGCT cis rs10089 0.953 rs7713860 chr5:127428789 G/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.8 7.74 0.57 3.04e-12 Ileal carcinoids; TGCT cis rs9503598 0.714 rs11242859 chr6:3454032 G/A cg00476032 chr6:3446245 SLC22A23 0.17 4.98 0.41 2.11e-6 Cognitive ability (multi-trait analysis);Cognitive ability;Intelligence (multi-trait analysis); TGCT cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg03396347 chr1:1875803 NA -0.36 -6.48 -0.5 1.93e-9 Body mass index; TGCT cis rs3935685 0.845 rs7175083 chr15:78006842 T/C cg03457338 chr15:78040120 NA -0.22 -5.75 -0.46 6.67e-8 Intelligence (multi-trait analysis); TGCT cis rs7474896 0.583 rs7071147 chr10:38003376 T/C cg25427524 chr10:38739819 LOC399744 -0.34 -5.47 -0.44 2.43e-7 Obesity (extreme); TGCT cis rs6570726 0.791 rs2096201 chr6:145934273 C/T cg13319975 chr6:146136371 FBXO30 -0.53 -4.75 -0.39 5.62e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs853679 0.517 rs1340004 chr6:28103691 C/T cg12963246 chr6:28129442 ZNF389 0.51 4.6 0.38 1.01e-5 Depression; TGCT cis rs3617 0.625 rs7620690 chr3:52891707 A/G cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.79 0.4 4.67e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs12220238 0.841 rs11001001 chr10:76097678 G/T cg19889307 chr10:75911429 ADK;AP3M1 0.88 6.38 0.5 3.27e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs7666738 0.546 rs10018080 chr4:98758436 C/A cg05340658 chr4:99064831 C4orf37 0.52 5.76 0.46 6.27e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs4746818 1.000 rs7901617 chr10:70904063 C/T cg04149295 chr10:70884716 VPS26A 0.76 5.36 0.43 3.98e-7 Left atrial antero-posterior diameter; TGCT cis rs548181 0.673 rs12288034 chr11:125570941 A/T cg03464685 chr11:125439445 EI24 -1.42 -9.3 -0.64 6.36e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs72843506 0.722 rs9902683 chr17:20015428 G/A cg18979559 chr17:20280153 CCDC144C -0.64 -4.8 -0.4 4.5e-6 Schizophrenia; TGCT cis rs1865760 0.613 rs9295674 chr6:25912342 A/G cg03264133 chr6:25882463 NA -0.53 -5.65 -0.45 1.06e-7 Height; TGCT cis rs1018836 0.828 rs10956730 chr8:91597428 T/G cg16814680 chr8:91681699 NA -0.69 -6.92 -0.53 2.14e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs17102423 0.964 rs868814 chr14:65584508 C/T cg11161011 chr14:65562177 MAX -0.46 -6.43 -0.5 2.45e-9 Obesity-related traits; TGCT trans rs931812 0.858 rs4734017 chr8:101912073 C/T cg20993868 chr7:22813445 NA 0.39 8.11 0.59 4.2e-13 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs10788575 0.950 rs79252540 chr10:89749671 G/A cg03166508 chr10:89453226 PAPSS2 0.35 4.85 0.4 3.69e-6 Type 2 diabetes; TGCT cis rs1005224 0.889 rs9323617 chr14:76158638 A/G cg25116370 chr14:76127843 TTLL5;C14orf1 -0.53 -4.57 -0.38 1.16e-5 Large artery stroke; TGCT cis rs9549367 0.789 rs2302754 chr13:113898385 C/T cg00898013 chr13:113819073 PROZ 0.4 4.94 0.41 2.45e-6 Platelet distribution width; TGCT cis rs8072100 0.713 rs9895776 chr17:45486003 A/G cg08085267 chr17:45401833 C17orf57 -0.52 -5.75 -0.46 6.48e-8 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT trans rs2727020 0.729 rs4980439 chr11:49342246 G/C cg15704280 chr7:45808275 SEPT13 -0.69 -7.78 -0.57 2.45e-12 Coronary artery disease; TGCT cis rs3774830 0.748 rs58854245 chr4:5466134 G/A cg26943120 chr4:5472116 STK32B 0.23 5.08 0.42 1.34e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs4975709 0.589 rs4975747 chr5:1862836 G/A cg04156016 chr5:1868137 NA 0.33 4.77 0.39 5.05e-6 Cardiovascular disease risk factors; TGCT cis rs4252435 0.520 rs7797908 chr7:142641207 T/C cg21621906 chr7:142494914 NA -1.08 -4.53 -0.38 1.36e-5 Cancer; TGCT cis rs6845621 0.727 rs13119001 chr4:18878532 T/A cg12196642 chr4:18937545 NA -0.24 -4.47 -0.37 1.74e-5 Adverse response to chemotherapy in breast cancer (alopecia) (cyclophosphamide+doxorubicin+/-5FU); TGCT cis rs12220898 0.749 rs10732631 chr10:50485910 T/C cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs10504229 0.683 rs6999984 chr8:58115079 G/A cg08280861 chr8:58055591 NA 0.4 4.67 0.39 7.79e-6 Developmental language disorder (linguistic errors); TGCT cis rs7000551 0.619 rs2443506 chr8:22373383 T/C cg12081754 chr8:22256438 SLC39A14 0.3 4.72 0.39 6.19e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2688608 0.620 rs7098444 chr10:75580042 C/T cg04320760 chr10:75533139 FUT11 -0.37 -5.72 -0.46 7.3900000000000007e-08 Inflammatory bowel disease; TGCT cis rs651907 0.640 rs1091664 chr3:101618690 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.63 6.01 0.47 1.92e-8 Colorectal cancer; TGCT cis rs7100689 0.646 rs4357632 chr10:82131783 C/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs4746818 1.000 rs4284308 chr10:70884861 C/T cg11621586 chr10:70884670 VPS26A 1.18 10.97 0.7 5.39e-20 Left atrial antero-posterior diameter; TGCT cis rs8177253 0.930 rs12595 chr3:133496553 T/C cg16414030 chr3:133502952 NA -0.61 -9.55 -0.65 1.59e-16 Iron status biomarkers; TGCT cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg25767906 chr1:53392781 SCP2 0.46 5.18 0.42 8.88e-7 Monocyte count; TGCT cis rs524281 0.861 rs6591207 chr11:65949674 A/T cg00563793 chr11:65837595 PACS1 0.57 4.99 0.41 2.02e-6 Electroencephalogram traits; TGCT cis rs7809950 0.954 rs2520242 chr7:107136320 G/T cg23024343 chr7:107201750 COG5 0.35 5.5 0.44 2.05e-7 Coronary artery disease; TGCT cis rs4699052 1.000 rs4699052 chr4:104137790 C/T cg16532752 chr4:104119610 CENPE -0.59 -5.56 -0.45 1.56e-7 Testicular germ cell tumor; TGCT cis rs4234284 0.556 rs4679147 chr3:126955702 C/T cg25436886 chr3:127056972 NA -0.47 -4.58 -0.38 1.1e-5 Adverse response to chemotherapy in breast cancer (alopecia) (docetaxel); TGCT cis rs4665809 0.531 rs12990692 chr2:26464939 C/T cg26119090 chr2:26468346 HADHA;HADHB 0.97 7.19 0.54 5.48e-11 Gut microbiome composition (summer); TGCT cis rs3785574 0.745 rs2854162 chr17:61975610 T/C cg01411255 chr17:61851458 DDX42;CCDC47 -1.04 -12.56 -0.75 7.35e-24 Height; TGCT cis rs4862750 0.832 rs10007858 chr4:187877492 A/G cg03452623 chr4:187889614 NA -0.36 -5.49 -0.44 2.17e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 1.000 rs58053450 chr8:58173348 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs10504229 0.593 rs77607045 chr8:58010464 T/C cg11062466 chr8:58055876 NA 0.43 4.52 0.38 1.45e-5 Developmental language disorder (linguistic errors); TGCT cis rs4499344 0.633 rs259258 chr19:33152523 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs7666738 0.546 rs10025064 chr4:98914060 A/G cg05340658 chr4:99064831 C4orf37 0.59 6.52 0.51 1.62e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs11122272 0.735 rs2790877 chr1:231535427 A/G cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.47 -0.5 2.07e-9 Hemoglobin concentration; TGCT cis rs28386778 0.897 rs2236736 chr17:61938248 G/T cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.02 0.41 1.78e-6 Prudent dietary pattern; TGCT cis rs9682041 0.696 rs35177863 chr3:170090006 A/G cg11886554 chr3:170076028 SKIL 0.6 4.76 0.39 5.35e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs11098499 0.754 rs714899 chr4:120243035 G/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs6665290 0.835 rs7549586 chr1:227214566 A/G cg10327440 chr1:227177885 CDC42BPA -0.98 -20.31 -0.88 2.98e-41 Myeloid white cell count; TGCT cis rs514406 0.893 rs512723 chr1:53343880 C/T cg16325326 chr1:53192061 ZYG11B -0.58 -6.76 -0.52 4.76e-10 Monocyte count; TGCT cis rs62244186 0.545 rs725866 chr3:44765533 A/G cg21672276 chr3:44754072 ZNF502 -0.54 -6.25 -0.49 5.94e-9 Depressive symptoms; TGCT cis rs3892630 0.588 rs2287881 chr19:33333155 A/G cg22980127 chr19:33182716 NUDT19 -0.7 -5.94 -0.47 2.72e-8 Red blood cell traits; TGCT cis rs28595532 0.841 rs114965278 chr4:119743694 T/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs4819052 1.000 rs2297286 chr21:46707897 C/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.99 8.17 0.59 3.09e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7937682 1.000 rs2186839 chr11:111534442 T/G cg09085632 chr11:111637200 PPP2R1B -1.05 -10.05 -0.67 9.54e-18 Primary sclerosing cholangitis; TGCT cis rs308447 0.522 rs309363 chr4:123658169 C/G cg10495464 chr4:123653540 BBS12;LOC729338 0.73 6.85 0.52 3e-10 Perceived unattractiveness to mosquitoes; TGCT cis rs3764400 0.567 rs2240120 chr17:46142144 C/T cg02340556 chr17:46797764 NA 0.41 4.47 0.37 1.72e-5 Body mass index; TGCT cis rs2033711 0.870 rs3764534 chr19:58929136 G/A cg12042659 chr19:58951599 ZNF132 0.52 4.66 0.39 7.87e-6 Uric acid clearance; TGCT cis rs3087591 0.919 rs2953004 chr17:29502723 C/T cg24425628 chr17:29625626 OMG;NF1 0.42 6.17 0.48 8.91e-9 Hip circumference; TGCT cis rs11626933 1.000 rs61989986 chr14:90739180 G/A cg14092571 chr14:90743983 NA -0.3 -6.23 -0.49 6.81e-9 Gut microbiota (bacterial taxa); TGCT cis rs4366490 0.796 rs1939756 chr11:62904525 A/G cg21002970 chr11:62369079 MTA2 0.87 4.67 0.39 7.78e-6 Conotruncal heart defects; TGCT cis rs56804039 0.524 rs7003826 chr8:8406190 A/G cg14215082 chr8:9055850 NA -0.45 -4.65 -0.39 8.38e-6 Cervical cancer; TGCT cis rs1018836 0.608 rs7843149 chr8:91474961 C/T cg16814680 chr8:91681699 NA -0.71 -7.18 -0.54 5.67e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs727563 0.520 rs132773 chr22:42031768 T/A cg06481639 chr22:41940642 POLR3H 0.73 6.47 0.5 2.04e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9383153 1.000 rs9370888 chr6:16335544 A/G cg14009473 chr6:15502099 JARID2 0.66 5.69 0.46 8.57e-8 Gambling; TGCT cis rs3820068 0.705 rs4646075 chr1:15827461 T/C cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs78487399 0.808 rs7573500 chr2:43685625 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.19 -0.42 8.37e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2562456 0.755 rs1879234 chr19:21704479 T/G cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs72945132 0.882 rs55915603 chr11:70210067 G/T cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs7666738 0.791 rs4699324 chr4:98967496 G/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1218582 0.744 rs6674853 chr1:154892753 G/C cg06221963 chr1:154839813 KCNN3 -0.79 -14.65 -0.8 7.83e-29 Prostate cancer; TGCT cis rs854765 0.583 rs950966 chr17:17783748 A/G cg09796270 chr17:17721594 SREBF1 -0.27 -5.5 -0.44 2.04e-7 Total body bone mineral density; TGCT cis rs13118159 0.550 rs11946956 chr4:1369094 T/G cg19318889 chr4:1322082 MAEA 0.28 6.78 0.52 4.46e-10 Longevity; TGCT cis rs7617773 1.000 rs6442108 chr3:48192959 G/C cg11946769 chr3:48343235 NME6 -0.59 -5.33 -0.43 4.54e-7 Coronary artery disease; TGCT cis rs832540 0.593 rs252912 chr5:56195792 C/T cg24531977 chr5:56204891 C5orf35 -0.56 -5.15 -0.42 9.92e-7 Coronary artery disease; TGCT cis rs9467773 1.000 rs9467779 chr6:26536687 A/T cg26531700 chr6:26746687 NA -0.47 -4.66 -0.39 7.93e-6 Intelligence (multi-trait analysis); TGCT cis rs2469997 1.000 rs2447164 chr8:120371887 G/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT trans rs9388451 0.839 rs10457469 chr6:126083658 G/A cg05039488 chr6:79577232 IRAK1BP1 -0.74 -8.38 -0.6 9.81e-14 Brugada syndrome; TGCT cis rs6570726 0.935 rs414222 chr6:145850482 C/T cg23711669 chr6:146136114 FBXO30 0.68 6.67 0.51 7.58e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.802 rs4822028 chr22:41789408 A/G cg13695892 chr22:41940480 POLR3H -0.77 -7.47 -0.56 1.24e-11 Vitiligo; TGCT cis rs78487399 0.808 rs6746632 chr2:43712163 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.14 -0.42 1.04e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7647973 0.593 rs58339610 chr3:49845006 T/A cg03060546 chr3:49711283 APEH -0.62 -5.56 -0.45 1.59e-7 Menarche (age at onset); TGCT cis rs4653767 1.000 rs708773 chr1:226920730 T/C cg10327440 chr1:227177885 CDC42BPA -0.47 -5.26 -0.43 6.02e-7 Parkinson's disease; TGCT cis rs2692947 0.568 rs57579941 chr2:96336253 T/C cg23100626 chr2:96804247 ASTL 0.41 4.75 0.39 5.46e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs911555 0.755 rs34411783 chr14:103900639 G/A cg12935359 chr14:103987150 CKB 0.34 4.53 0.38 1.35e-5 Intelligence (multi-trait analysis); TGCT cis rs7772486 0.641 rs2253757 chr6:146199686 C/T cg13319975 chr6:146136371 FBXO30 -0.66 -5.93 -0.47 2.83e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs7450817 chr6:8481421 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs11122272 0.735 rs2808592 chr1:231523757 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs17780086 0.529 rs7406406 chr17:30220153 T/G cg13647721 chr17:30228624 UTP6 0.6 5.32 0.43 4.72e-7 Height; TGCT cis rs8084125 1.000 rs72978665 chr18:74953641 A/G cg05528293 chr18:74961138 GALR1 0.52 5.16 0.42 9.72e-7 Obesity-related traits; TGCT cis rs7847628 0.587 rs4837796 chr9:123610288 A/G cg09586646 chr9:123605570 PSMD5;LOC253039 -0.55 -6.55 -0.51 1.37e-9 Birth weight; TGCT cis rs7100689 0.646 rs11202724 chr10:82136190 T/C cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs5769707 0.967 rs5769698 chr22:49997706 A/G cg05373962 chr22:49881684 NA -0.31 -6.26 -0.49 5.87e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7829975 0.533 rs13274028 chr8:8729193 A/C cg06636001 chr8:8085503 FLJ10661 0.69 6.29 0.49 4.95e-9 Mood instability; TGCT cis rs7824557 0.628 rs11994376 chr8:11202960 G/A cg21775007 chr8:11205619 TDH 0.69 6.81 0.52 3.8e-10 Retinal vascular caliber; TGCT cis rs6558530 0.698 rs7015858 chr8:1724307 C/T cg09410841 chr8:1729607 CLN8 0.87 9.95 0.67 1.7e-17 Systolic blood pressure; TGCT cis rs28386778 0.897 rs2727328 chr17:61923564 G/A cg06873352 chr17:61820015 STRADA 0.58 6.42 0.5 2.65e-9 Prudent dietary pattern; TGCT cis rs7552404 1.000 rs11161521 chr1:76216330 T/C cg03433033 chr1:76189801 ACADM 0.81 9.52 0.65 1.84e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7829975 0.535 rs17683510 chr8:8500724 A/G cg15556689 chr8:8085844 FLJ10661 0.54 5.15 0.42 1.01e-6 Mood instability; TGCT cis rs4819052 0.918 rs34886433 chr21:46680538 G/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.67 4.52 0.38 1.43e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2013441 1.000 rs3850783 chr17:20184501 C/T cg23224458 chr17:20280056 CCDC144C 0.38 4.61 0.38 9.96e-6 Obesity-related traits; TGCT cis rs7552404 0.731 rs10732723 chr1:76392437 C/T cg22875332 chr1:76189707 ACADM -0.68 -7.0 -0.53 1.41e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs1862618 0.573 rs2591962 chr5:56237155 G/A cg12311346 chr5:56204834 C5orf35 0.83 7.78 0.57 2.41e-12 Initial pursuit acceleration; TGCT cis rs2153535 0.580 rs2143356 chr6:8517675 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs7085104 0.572 rs284857 chr10:104574063 C/T cg05855489 chr10:104503620 C10orf26 -0.65 -6.52 -0.51 1.57e-9 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs5750830 0.645 rs4821890 chr22:39777523 G/A cg05872129 chr22:39784769 NA -0.9 -10.38 -0.68 1.51e-18 Intelligence (multi-trait analysis); TGCT cis rs921968 0.541 rs7604319 chr2:219538799 A/C cg02176678 chr2:219576539 TTLL4 -0.5 -6.93 -0.53 2.02e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs114540395 0.687 rs75269434 chr10:103473111 G/C cg24291461 chr10:102749544 C10orf2 0.35 4.54 0.38 1.29e-5 Schizophrenia; TGCT cis rs11030122 0.592 rs4910880 chr11:4084630 C/G cg18678763 chr11:4115507 RRM1 -0.46 -5.67 -0.45 9.61e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs3780378 0.967 rs7863219 chr9:5046548 A/C cg02405213 chr9:5042618 JAK2 -0.59 -7.49 -0.56 1.13e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs698833 0.518 rs7562945 chr2:44552772 G/T cg23552047 chr2:44669647 C2orf34 0.29 4.66 0.39 8.08e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs637571 0.522 rs679581 chr11:65746653 A/G cg17985854 chr11:65770987 BANF1;EIF1AD 0.21 4.51 0.38 1.47e-5 Eosinophil percentage of white cells; TGCT cis rs9640161 0.750 rs11538922 chr7:150035183 C/T cg10018233 chr7:150070692 REPIN1 0.32 4.59 0.38 1.09e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs2880765 0.835 rs4526974 chr15:86024284 C/T cg13263323 chr15:86062960 AKAP13 -0.23 -4.99 -0.41 2e-6 Coronary artery disease; TGCT cis rs11249608 0.789 rs6868425 chr5:178446708 A/G cg01312482 chr5:178451176 ZNF879 -0.55 -5.41 -0.44 3.08e-7 Pubertal anthropometrics; TGCT cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg16325326 chr1:53192061 ZYG11B -0.7 -8.6 -0.61 2.93e-14 Monocyte count; TGCT cis rs2721195 0.719 rs4925811 chr8:145802447 G/T cg15320075 chr8:145703422 NA -0.73 -7.36 -0.55 2.21e-11 Age at first birth; TGCT cis rs2034088 0.507 rs11650424 chr17:435896 C/T cg04370829 chr17:406249 NA -0.36 -4.47 -0.37 1.73e-5 Hip circumference adjusted for BMI; TGCT cis rs9467711 1.000 rs6923139 chr6:26313348 C/T cg02458000 chr6:26745757 NA -1.05 -5.8 -0.46 5.29e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs2224391 0.628 rs2773304 chr6:5242602 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -1.02 -6.56 -0.51 1.33e-9 Height; TGCT cis rs10791097 0.653 rs11222362 chr11:130731425 T/C cg12179176 chr11:130786555 SNX19 0.77 9.52 0.65 1.82e-16 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7666738 0.830 rs13129503 chr4:98987892 T/C cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs75059851 1.000 rs3758927 chr11:133829644 C/G cg14047540 chr11:133829660 NA 0.49 5.07 0.41 1.38e-6 Schizophrenia; TGCT cis rs1692580 0.807 rs10910036 chr1:2183754 C/G cg21194808 chr1:2205498 SKI 0.29 5.59 0.45 1.38e-7 Coronary artery disease; TGCT cis rs7104764 0.917 rs6598067 chr11:243093 T/C cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.19 0.71 1.61e-20 Menarche (age at onset); TGCT cis rs798766 1.000 rs798724 chr4:1704643 C/T cg05874882 chr4:1763078 NA -0.38 -5.23 -0.43 6.87e-7 Bladder cancer;Urinary bladder cancer; TGCT cis rs6545883 0.965 rs10186325 chr2:61757721 G/T cg15711740 chr2:61764176 XPO1 -0.57 -5.46 -0.44 2.51e-7 Tuberculosis; TGCT cis rs74544699 1.000 rs11508014 chr4:74837510 A/G cg16072462 chr4:74847758 PF4 0.76 4.86 0.4 3.49e-6 Growth-regulated protein alpha levels; TGCT cis rs858239 0.571 rs6953020 chr7:23172132 T/C cg05602783 chr7:23145260 KLHL7 -0.6 -4.99 -0.41 1.96e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg24675658 chr1:53192096 ZYG11B -0.77 -9.64 -0.65 9.38e-17 Monocyte count; TGCT cis rs8072100 0.870 rs10432035 chr17:45624913 G/C cg08085267 chr17:45401833 C17orf57 0.44 4.89 0.4 3.12e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs3820928 0.874 rs4675137 chr2:227883910 G/C cg11843606 chr2:227700838 RHBDD1 -0.54 -4.94 -0.41 2.51e-6 Pulmonary function; TGCT cis rs9611565 0.729 rs203319 chr22:41914593 C/T cg13695892 chr22:41940480 POLR3H -0.86 -9.02 -0.63 2.98e-15 Vitiligo; TGCT cis rs523522 1.000 rs1563333 chr12:120934407 C/T cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs28386778 0.897 rs1043127 chr17:61791210 T/G cg22520471 chr17:61851767 DDX42;CCDC47 0.54 4.88 0.4 3.18e-6 Prudent dietary pattern; TGCT cis rs12908161 1.000 rs12899981 chr15:85302373 G/A cg11189052 chr15:85197271 WDR73 0.71 5.82 0.46 4.67e-8 Schizophrenia; TGCT cis rs2836974 0.584 rs34436313 chr21:40685246 A/G cg11890956 chr21:40555474 PSMG1 -0.76 -7.08 -0.54 9.53e-11 Cognitive function; TGCT cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg16497277 chr3:49208875 KLHDC8B -0.54 -5.17 -0.42 9.07e-7 Menarche (age at onset); TGCT cis rs62244186 0.520 rs2372828 chr3:44784949 A/G cg02073558 chr3:44770973 ZNF501 -0.73 -7.31 -0.55 2.81e-11 Depressive symptoms; TGCT cis rs7772486 0.658 rs6570706 chr6:145962922 T/C cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.547 rs11177 chr3:52721305 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs61990749 0.597 rs717683 chr14:78255453 A/G cg23188588 chr14:78226832 SNW1;C14orf178 0.64 4.5 0.37 1.54e-5 Fibroblast growth factor basic levels; TGCT cis rs10037055 1.000 rs6886255 chr5:176718361 A/G cg18465082 chr5:176734745 MXD3 -0.29 -4.55 -0.38 1.28e-5 Migraine without aura; TGCT cis rs1048238 0.846 rs945417 chr1:16344625 C/G cg21385522 chr1:16154831 NA 0.43 4.52 0.38 1.43e-5 Systolic blood pressure; TGCT cis rs9527 0.615 rs10883810 chr10:104727224 A/C cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs1008375 1.000 rs3933453 chr4:17636319 A/C cg16339924 chr4:17578868 LAP3 0.66 5.43 0.44 2.82e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs28374715 0.681 rs28687846 chr15:41599902 C/T cg18705301 chr15:41695430 NDUFAF1 -0.9 -14.62 -0.8 9.13e-29 Ulcerative colitis; TGCT cis rs9911578 0.935 rs9893351 chr17:57023326 G/A cg05425664 chr17:57184151 TRIM37 -0.56 -5.42 -0.44 2.99e-7 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.539 rs4841012 chr8:8551710 C/A cg17143192 chr8:8559678 CLDN23 -0.49 -4.94 -0.41 2.44e-6 Mood instability; TGCT cis rs6840360 0.615 rs3828546 chr4:152679816 A/G cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.63e-8 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg03188948 chr7:1209495 NA 0.47 6.54 0.51 1.47e-9 Longevity;Endometriosis; TGCT cis rs319204 1.000 rs1380014 chr5:146235722 A/G cg25021259 chr5:146258546 PPP2R2B 0.35 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs79387448 0.745 rs59694233 chr2:103116521 G/A cg09003973 chr2:102972529 NA 0.85 5.61 0.45 1.25e-7 Gut microbiota (bacterial taxa); TGCT cis rs12478296 1.000 rs56162244 chr2:243018690 A/G cg06360820 chr2:242988706 NA -0.59 -4.83 -0.4 3.89e-6 Obesity-related traits; TGCT cis rs6450176 0.638 rs11746856 chr5:53291295 A/C ch.5.1024479R chr5:53302184 ARL15 -0.77 -5.46 -0.44 2.46e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs1153858 0.945 rs7182300 chr15:45634928 G/A cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs1165205 0.558 rs793144 chr6:25879321 C/T cg15691649 chr6:25882328 NA -0.56 -7.3 -0.55 3.04e-11 Urate levels; TGCT cis rs2070488 0.775 rs6599211 chr3:38558830 A/G cg01465620 chr3:38496096 LOC100128640;ACVR2B -0.71 -6.89 -0.53 2.46e-10 Electrocardiographic conduction measures; TGCT cis rs9326248 0.954 rs4938349 chr11:117021923 C/T cg26566898 chr11:117069891 TAGLN 0.33 4.52 0.38 1.41e-5 Blood protein levels; TGCT cis rs3858704 0.517 rs7297186 chr12:111778178 C/T cg10833066 chr12:111807467 FAM109A -0.41 -8.01 -0.58 6.96e-13 Idiopathic osteonecrosis of the femoral head; TGCT cis rs7246657 0.943 rs10426666 chr19:37828514 C/G cg18154014 chr19:37997991 ZNF793 0.97 6.49 0.5 1.82e-9 Coronary artery calcification; TGCT cis rs10771431 0.597 rs10843142 chr12:9357502 A/G cg21349645 chr12:9436242 LOC642846 -0.45 -4.59 -0.38 1.08e-5 Breast size; TGCT cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg20607798 chr8:58055168 NA 0.45 4.62 0.38 9.57e-6 Developmental language disorder (linguistic errors); TGCT cis rs7647973 0.516 rs4499638 chr3:49202782 C/G cg18654377 chr3:49208889 KLHDC8B -0.38 -4.96 -0.41 2.25e-6 Menarche (age at onset); TGCT cis rs9419702 0.614 rs4897816 chr10:133533646 G/A cg23460707 chr10:133558971 NA 0.42 4.63 0.38 9.08e-6 Survival in rectal cancer; TGCT cis rs12681287 0.752 rs4641037 chr8:87268379 A/G cg27223183 chr8:87520930 FAM82B -0.8 -5.69 -0.46 8.66e-8 Caudate activity during reward; TGCT cis rs2296887 0.841 rs7913281 chr10:104010142 A/G cg26089160 chr10:104170217 PSD -0.61 -5.62 -0.45 1.19e-7 Parkinson's disease; TGCT cis rs10504229 0.815 rs72650877 chr8:58164510 T/C cg08280861 chr8:58055591 NA 0.39 4.76 0.39 5.35e-6 Developmental language disorder (linguistic errors); TGCT cis rs801193 0.875 rs13227951 chr7:66213108 C/T cg18876405 chr7:65276391 NA -0.37 -5.75 -0.46 6.62e-8 Aortic root size; TGCT cis rs1799949 0.860 rs8176279 chr17:41210396 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.45 4.67 0.39 7.86e-6 Menopause (age at onset); TGCT cis rs8050907 0.744 rs8047271 chr16:4536634 A/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs1865760 0.516 rs10807007 chr6:26048931 A/C cg16482183 chr6:26056742 HIST1H1C 0.57 5.0 0.41 1.93e-6 Height; TGCT cis rs713587 0.776 rs1172294 chr2:25169200 A/G cg01884057 chr2:25150051 NA 0.39 7.97 0.58 8.81e-13 Body mass index in non-asthmatics; TGCT cis rs9611565 0.592 rs4822038 chr22:41958495 G/A cg03806693 chr22:41940476 POLR3H -1.09 -11.81 -0.73 4.98e-22 Vitiligo; TGCT cis rs12579753 0.879 rs12579544 chr12:82164043 A/C cg21231944 chr12:82153410 PPFIA2 -0.34 -4.62 -0.38 9.52e-6 Resting heart rate; TGCT cis rs7267979 0.816 rs6115094 chr20:25210827 A/G cg14121845 chr20:25566513 NINL 0.46 4.68 0.39 7.51e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9303401 0.573 rs62081879 chr17:57181524 C/T cg25039879 chr17:56429692 SUPT4H1 0.55 4.9 0.4 2.93e-6 Cognitive test performance; TGCT cis rs308447 0.516 rs13142203 chr4:123679002 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.66 6.42 0.5 2.63e-9 Perceived unattractiveness to mosquitoes; TGCT cis rs3617 0.625 rs11719137 chr3:52876389 G/T cg05573699 chr3:52720067 GNL3;PBRM1 0.49 4.77 0.39 5.04e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 1.000 rs73607875 chr8:58173522 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7726839 0.574 rs11134148 chr5:637107 C/T cg09021430 chr5:549028 NA -0.38 -5.11 -0.42 1.21e-6 Obesity-related traits; TGCT cis rs9322193 0.962 rs4380763 chr6:149999222 A/G cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs1670533 1.000 rs12645644 chr4:1054159 C/T cg20887711 chr4:1340912 KIAA1530 0.6 5.06 0.41 1.48e-6 Recombination rate (females); TGCT cis rs6570726 0.791 rs6923074 chr6:145893332 T/C cg23711669 chr6:146136114 FBXO30 0.86 9.54 0.65 1.64e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs11190604 1.000 rs2489039 chr10:102328036 T/A cg23241863 chr10:102295624 HIF1AN 0.67 5.1 0.42 1.23e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7666738 0.830 rs2167892 chr4:99048503 G/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs9653442 0.510 rs11891046 chr2:100794402 C/G cg22139774 chr2:100720529 AFF3 -0.33 -5.24 -0.43 6.61e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7843479 0.601 rs10109521 chr8:21829948 G/A cg17168535 chr8:21777572 XPO7 0.8 8.11 0.59 4.09e-13 Mean corpuscular volume; TGCT cis rs17345786 0.906 rs11710016 chr3:101120030 A/C cg12386194 chr3:101231763 SENP7 -0.65 -6.39 -0.5 3.06e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs751728 0.626 rs6457741 chr6:33756026 C/T cg13859433 chr6:33739653 LEMD2 -0.33 -5.75 -0.46 6.65e-8 Crohn's disease; TGCT cis rs5769707 0.681 rs2319346 chr22:50029640 A/G cg05373962 chr22:49881684 NA -0.3 -5.26 -0.43 6.23e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1552244 0.572 rs73117481 chr3:10160132 C/T cg00149659 chr3:10157352 C3orf10 1.17 7.24 0.55 4.13e-11 Alzheimer's disease; TGCT cis rs617219 0.710 rs2607141 chr5:78558635 G/T cg23514016 chr5:78407564 BHMT 0.32 4.87 0.4 3.38e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs28386778 0.897 rs2044125 chr17:61863184 A/C cg23090583 chr17:61904693 PSMC5;FTSJ3 -1.09 -16.13 -0.82 3.1e-32 Prudent dietary pattern; TGCT cis rs8017423 0.967 rs11624725 chr14:90713609 G/T cg04374321 chr14:90722782 PSMC1 -0.72 -7.31 -0.55 2.85e-11 Mortality in heart failure; TGCT cis rs9814567 0.896 rs58491661 chr3:134355189 G/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.84 7.7 0.57 3.76e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs797680 0.856 rs7540025 chr1:93759228 C/T cg27528825 chr2:159282178 CCDC148 0.34 6.71 0.52 6.19e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs11722228 0.508 rs2241472 chr4:10085902 C/G cg26043149 chr18:55253948 FECH 1.15 11.21 0.71 1.41e-20 Gout;Urate levels;Serum uric acid levels; TGCT cis rs2739330 0.731 rs2000468 chr22:24241611 G/T cg18538332 chr22:24372958 LOC391322 -0.86 -9.78 -0.66 4.35e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9300255 0.602 rs10846486 chr12:123709927 G/A cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs2180341 0.961 rs7774468 chr6:127592501 G/C cg24812749 chr6:127587940 RNF146 0.99 7.72 0.57 3.33e-12 Breast cancer; TGCT cis rs910316 0.763 rs4556 chr14:75476071 G/C cg08847533 chr14:75593920 NEK9 0.83 8.89 0.62 5.99e-15 Height; TGCT cis rs4819052 0.851 rs1056099 chr21:46678892 G/A cg06618935 chr21:46677482 NA -0.36 -5.5 -0.44 2.06e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6424115 0.830 rs6673210 chr1:24203534 A/G cg15997130 chr1:24165203 NA 0.85 8.93 0.63 4.81e-15 Immature fraction of reticulocytes; TGCT cis rs806215 0.526 rs12668077 chr7:127476253 T/C cg11539674 chr7:127291444 SND1 -0.36 -4.67 -0.39 7.77e-6 Type 2 diabetes; TGCT cis rs10782582 0.609 rs80059220 chr1:76279112 G/T cg10523679 chr1:76189770 ACADM -0.58 -5.38 -0.43 3.6e-7 Daytime sleep phenotypes; TGCT cis rs11650494 0.908 rs77338752 chr17:47372328 A/C cg08112188 chr17:47440006 ZNF652 1.04 5.35 0.43 4.09e-7 Prostate cancer; TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg07167872 chr1:205819463 PM20D1 0.68 9.92 0.67 2.01e-17 Menarche (age at onset); TGCT cis rs9486719 0.843 rs2499793 chr6:96846402 A/C cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs8062405 0.540 rs193628 chr16:28582142 G/T cg09754948 chr16:28834200 ATXN2L -0.54 -4.46 -0.37 1.82e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7267979 1.000 rs2482937 chr20:25340786 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10751667 0.621 rs10794351 chr11:946228 C/T cg06064525 chr11:970664 AP2A2 -0.35 -8.29 -0.6 1.6e-13 Alzheimer's disease (late onset); TGCT cis rs10504229 0.906 rs112793785 chr8:58190537 T/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9649213 0.614 rs3944111 chr7:98005766 C/T cg09267113 chr7:98030324 BAIAP2L1 -0.92 -8.65 -0.61 2.22e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs875971 1.000 rs7789554 chr7:65946038 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs74233809 1.000 rs12221335 chr10:104769392 T/A cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs10992471 0.756 rs7027595 chr9:95131553 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.61 -6.29 -0.49 4.96e-9 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs875971 0.862 rs2909688 chr7:65841612 C/A cg11764359 chr7:65958608 NA 0.55 5.09 0.42 1.29e-6 Aortic root size; TGCT cis rs7584330 0.554 rs4420668 chr2:238444793 G/A cg08992911 chr2:238395768 MLPH 0.64 4.49 0.37 1.63e-5 Prostate cancer; TGCT cis rs7178572 1.000 rs952472 chr15:77776562 A/C cg15453836 chr15:77711506 NA -0.4 -4.59 -0.38 1.07e-5 Type 2 diabetes; TGCT cis rs2153535 0.580 rs6927589 chr6:8456632 A/G cg23788917 chr6:8435910 SLC35B3 -0.59 -5.34 -0.43 4.23e-7 Motion sickness; TGCT cis rs79349575 0.681 rs56080003 chr17:47019049 A/T cg26022315 chr17:47021804 SNF8 0.49 4.9 0.4 2.94e-6 Type 2 diabetes; TGCT cis rs6964587 1.000 rs11982047 chr7:91705274 G/A cg17063962 chr7:91808500 NA 0.88 9.54 0.65 1.69e-16 Breast cancer; TGCT cis rs12681287 0.547 rs56752411 chr8:87515156 C/T cg27223183 chr8:87520930 FAM82B -0.96 -7.08 -0.54 9.31e-11 Caudate activity during reward; TGCT cis rs7681440 0.904 rs28777703 chr4:90769924 A/G cg20003494 chr4:90757398 SNCA 0.57 5.39 0.44 3.41e-7 Dementia with Lewy bodies; TGCT cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg12310025 chr6:25882481 NA -0.55 -5.58 -0.45 1.41e-7 Blood metabolite levels; TGCT cis rs17826219 0.568 rs9907834 chr17:29154013 G/A cg14008862 chr17:28927542 LRRC37B2 0.75 5.06 0.41 1.5e-6 Body mass index; TGCT cis rs2677744 1.000 rs1266489 chr15:91458485 G/A cg23684204 chr15:91497937 RCCD1 0.34 5.09 0.42 1.28e-6 Attention deficit hyperactivity disorder; TGCT cis rs4409766 0.518 rs486955 chr10:104546284 C/T cg05855489 chr10:104503620 C10orf26 -0.76 -5.24 -0.43 6.78e-7 Hypertension;Systolic blood pressure;Diastolic blood pressure (long-term average);Body mass index;Diastolic blood pressure;Mean arterial pressure (long-term average); TGCT cis rs3540 0.533 rs937793 chr15:91053583 A/G cg22089800 chr15:90895588 ZNF774 -0.71 -7.3 -0.55 3.08e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs6088580 0.634 rs6579165 chr20:32994715 A/G cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs1461503 0.932 rs10892944 chr11:122843895 T/C cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs1635 1.000 rs1635 chr6:28227604 C/A cg15743358 chr6:28303923 ZNF323 -1.1 -4.55 -0.38 1.25e-5 Schizophrenia; TGCT trans rs35365539 1 rs35365539 chr3:49794347 A/AC cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Blood protein levels; TGCT cis rs514406 0.861 rs2065477 chr1:53250213 C/T cg16325326 chr1:53192061 ZYG11B 0.71 8.65 0.61 2.18e-14 Monocyte count; TGCT cis rs8068544 0.818 rs75771390 chr17:40194054 A/G cg13092355 chr17:39992602 KLHL10;NT5C3L -0.95 -4.46 -0.37 1.84e-5 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs7618915 0.547 rs12496476 chr3:52708737 A/G cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs2235642 0.785 rs1057983 chr16:1660274 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.28 -5.02 -0.41 1.78e-6 Coronary artery disease; TGCT cis rs11122272 0.701 rs971533 chr1:231522097 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 8.11 0.59 4.07e-13 Platelet count; TGCT cis rs4689388 0.581 rs4476672 chr4:6281496 A/G cg25554036 chr4:6271136 WFS1 0.56 6.58 0.51 1.21e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs853679 0.517 rs9295761 chr6:28147987 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs8084125 0.832 rs62105178 chr18:74950635 C/T cg15443732 chr18:74961078 GALR1 0.48 4.7 0.39 6.76e-6 Obesity-related traits; TGCT cis rs11651000 0.857 rs56172120 chr17:45824904 G/A cg06532163 chr17:45867833 NA 0.36 5.24 0.43 6.81e-7 IgG glycosylation; TGCT cis rs4478858 0.647 rs10798836 chr1:31709214 C/T cg00250761 chr1:31883323 NA -0.27 -4.9 -0.4 2.89e-6 Alcohol dependence; TGCT cis rs10504229 0.906 rs903718 chr8:58167726 A/G cg21724239 chr8:58056113 NA 0.39 5.28 0.43 5.67e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.830 rs1834647 chr4:98882915 G/A cg17366294 chr4:99064904 C4orf37 0.71 7.28 0.55 3.33e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg02953382 chr22:24373134 LOC391322 -0.78 -8.12 -0.59 4.06e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7552404 1.000 rs4646961 chr1:76217169 G/A cg03433033 chr1:76189801 ACADM 0.81 9.52 0.65 1.84e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7618915 0.547 rs2878726 chr3:52748271 C/G cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs6969780 0.722 rs985652 chr7:27198083 A/C cg17457637 chr7:27170717 HOXA4 -0.44 -4.74 -0.39 5.67e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs459571 0.839 rs10993895 chr9:136887726 C/T cg14405625 chr9:136855902 VAV2 0.3 4.52 0.38 1.44e-5 Platelet distribution width; TGCT cis rs7605378 0.567 rs717915 chr2:200714766 C/T cg19045956 chr2:200819837 C2orf60;C2orf47 0.57 6.13 0.48 1.1e-8 Osteoporosis; TGCT cis rs7605378 0.752 rs769960 chr2:200710706 G/T cg23649088 chr2:200775458 C2orf69 -0.42 -7.46 -0.56 1.33e-11 Osteoporosis; TGCT cis rs1865760 0.865 rs2164485 chr6:25952106 G/A cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT cis rs7617773 0.817 rs3729577 chr3:48228994 A/C cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs4285028 0.948 rs35902163 chr3:121649526 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT trans rs208520 0.706 rs851601 chr6:66893853 G/A cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -10.21 -0.68 4.02e-18 Exhaled nitric oxide output; TGCT cis rs10875595 0.836 rs56756237 chr5:140678342 T/C cg24830062 chr5:140700576 TAF7 -0.63 -5.29 -0.43 5.35e-7 Pulmonary function decline; TGCT cis rs2243480 1.000 rs34974928 chr7:65364006 T/C cg22121687 chr7:65037720 NA -0.78 -4.7 -0.39 6.74e-6 Diabetic kidney disease; TGCT trans rs551517 0.522 rs2766982 chr9:113641725 T/A cg18410444 chr5:89825535 LYSMD3 0.66 6.66 0.51 8.12e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs12477438 0.798 rs1580068 chr2:99649969 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.7 -6.1 -0.48 1.22e-8 Chronic sinus infection; TGCT cis rs7659604 0.537 rs6823818 chr4:122731699 G/C cg20573242 chr4:122745356 CCNA2 0.62 5.48 0.44 2.23e-7 Type 2 diabetes; TGCT cis rs425277 0.565 rs61775448 chr1:2045376 A/G cg24578937 chr1:2090814 PRKCZ -0.23 -5.54 -0.45 1.73e-7 Height; TGCT cis rs904251 0.523 rs2776920 chr6:37480605 G/A cg25019722 chr6:37503610 NA -0.53 -7.98 -0.58 8.18e-13 Cognitive performance; TGCT cis rs2721195 0.683 rs6989368 chr8:145813457 A/G cg15320075 chr8:145703422 NA 0.64 5.8 0.46 5.3e-8 Age at first birth; TGCT cis rs11105298 0.891 rs10858903 chr12:89927972 G/A cg00757033 chr12:89920650 WDR51B 0.3 4.65 0.39 8.21e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7809950 1.000 rs1544336 chr7:107082415 G/C cg23024343 chr7:107201750 COG5 -0.36 -5.64 -0.45 1.11e-7 Coronary artery disease; TGCT cis rs17401966 0.838 rs2105212 chr1:10281012 T/C cg19773385 chr1:10388646 KIF1B -0.23 -5.03 -0.41 1.71e-6 Hepatocellular carcinoma; TGCT cis rs2019137 0.560 rs11123172 chr2:113984303 C/T cg21550016 chr2:113992930 PAX8;LOC440839;LOC654433 -0.52 -5.81 -0.46 4.88e-8 Lymphocyte counts; TGCT cis rs514406 0.825 rs12089511 chr1:53436427 A/T cg25767906 chr1:53392781 SCP2 0.5 5.94 0.47 2.65e-8 Monocyte count; TGCT cis rs9902453 0.904 rs4375718 chr17:28363642 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.06 -0.59 5.38e-13 Coffee consumption (cups per day); TGCT cis rs11105298 0.891 rs10858865 chr12:89846476 G/A cg00757033 chr12:89920650 WDR51B 0.34 5.36 0.43 4e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7647973 0.516 rs4955418 chr3:49200627 A/G cg18654377 chr3:49208889 KLHDC8B -0.38 -4.96 -0.41 2.25e-6 Menarche (age at onset); TGCT cis rs7666738 0.715 rs3857216 chr4:99032129 G/T cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs473651 0.503 rs515342 chr2:239367296 A/G cg08773314 chr2:239334832 ASB1 -0.41 -4.87 -0.4 3.37e-6 Multiple system atrophy; TGCT cis rs3862435 0.706 rs2253425 chr15:90945759 G/A cg14166756 chr15:90894880 ZNF774 -0.28 -4.61 -0.38 9.95e-6 Response to exercise (triglyceride level interaction); TGCT cis rs1975974 0.549 rs4889746 chr17:21745187 T/C cg18423549 chr17:21743878 NA -0.66 -6.21 -0.49 7.18e-9 Psoriasis; TGCT cis rs17172199 0.908 rs75148026 chr7:43335242 G/A cg04651707 chr7:43622869 STK17A 0.89 4.43 0.37 2.01e-5 Alzheimer's disease (cognitive decline); TGCT cis rs6138458 1.000 rs227631 chr20:24913653 A/G cg26195577 chr20:24973756 C20orf3 1.2 12.04 0.73 1.35e-22 Blood protein levels; TGCT trans rs8073060 0.586 rs72829927 chr17:34049992 A/G cg19694781 chr19:47549865 TMEM160 0.6 13.37 0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs933688 0.877 rs10474352 chr5:90732225 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 8.73 0.62 1.47e-14 Smoking behavior; TGCT cis rs1801251 0.896 rs921054 chr2:233694673 G/A cg08000102 chr2:233561755 GIGYF2 -0.57 -6.03 -0.48 1.74e-8 Coronary artery disease; TGCT cis rs3540 0.960 rs11853271 chr15:91025830 C/T cg22089800 chr15:90895588 ZNF774 0.74 7.14 0.54 6.77e-11 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs7267979 0.966 rs8123949 chr20:25388133 C/T cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1218582 0.744 rs6674853 chr1:154892753 G/C cg16680214 chr1:154839983 KCNN3 -0.42 -9.45 -0.65 2.78e-16 Prostate cancer; TGCT cis rs10504229 0.861 rs6990796 chr8:58183097 G/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs9894429 0.550 rs6565617 chr17:79612333 G/A cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs12908161 0.853 rs11633788 chr15:85305142 T/A cg11189052 chr15:85197271 WDR73 0.64 5.89 0.47 3.32e-8 Schizophrenia; TGCT cis rs8180040 0.647 rs57756484 chr3:47239333 A/G cg27129171 chr3:47204927 SETD2 -0.7 -8.35 -0.6 1.13e-13 Colorectal cancer; TGCT cis rs981844 0.740 rs6858578 chr4:154682058 G/T cg14289246 chr4:154710475 SFRP2 -0.89 -8.12 -0.59 3.89e-13 Response to statins (LDL cholesterol change); TGCT cis rs986417 1.000 rs1269984 chr14:60898138 C/G cg27398547 chr14:60952738 C14orf39 -1.42 -8.68 -0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs9383153 0.625 rs1886349 chr6:16320320 G/A cg06493612 chr6:15502050 JARID2 0.64 4.81 0.4 4.21e-6 Gambling; TGCT cis rs7582180 0.625 rs12612755 chr2:100906061 T/C cg08017756 chr2:100939284 LONRF2 -0.28 -4.76 -0.39 5.37e-6 Intelligence (multi-trait analysis); TGCT cis rs7267979 0.844 rs6115188 chr20:25432170 G/T cg14121845 chr20:25566513 NINL 0.45 4.6 0.38 1.03e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10782582 0.609 rs1796827 chr1:76391536 A/T cg10523679 chr1:76189770 ACADM -0.52 -4.73 -0.39 5.94e-6 Daytime sleep phenotypes; TGCT cis rs748404 0.631 rs11070399 chr15:43646347 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.46 4.72 0.39 6.3e-6 Lung cancer; TGCT cis rs9522267 0.535 rs9522301 chr13:112236726 A/T cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.78e-6 Hepatitis; TGCT cis rs11578119 0.933 rs12128573 chr1:170391126 C/T cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.67e-8 Male-pattern baldness; TGCT cis rs3820068 0.705 rs1800616 chr1:15832229 G/A cg05660106 chr1:15850417 CASP9 1.16 14.41 0.79 2.88e-28 Systolic blood pressure; TGCT cis rs35306767 0.903 rs11816064 chr10:931176 A/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs9914544 0.678 rs28374894 chr17:18761659 C/A cg26378065 chr17:18585709 ZNF286B 0.52 4.5 0.37 1.56e-5 Educational attainment (years of education); TGCT cis rs981844 1.000 rs2251997 chr4:154654067 A/G cg14289246 chr4:154710475 SFRP2 -1.0 -8.6 -0.61 2.88e-14 Response to statins (LDL cholesterol change); TGCT cis rs7811142 1.000 rs74460138 chr7:100027339 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.07 -9.63 -0.65 1.01e-16 Platelet count; TGCT cis rs10790268 1 rs10790268 chr11:118729391 A/G cg19308663 chr11:118741387 NA -0.32 -5.88 -0.47 3.6e-8 Rheumatoid arthritis; TGCT cis rs1008375 0.898 rs9998130 chr4:17593905 A/G cg18681998 chr4:17616180 MED28 0.88 8.14 0.59 3.56e-13 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10791097 0.592 rs4936122 chr11:130734264 A/C cg14779329 chr11:130786720 SNX19 0.29 4.91 0.4 2.77e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs231513 0.954 rs231505 chr17:41970268 A/T cg26893861 chr17:41843967 DUSP3 0.63 4.86 0.4 3.49e-6 Cognitive function; TGCT cis rs2370759 1.000 rs11594459 chr10:32561858 A/C cg01819863 chr10:32635814 EPC1 1.01 9.98 0.67 1.45e-17 Sexual dysfunction (female); TGCT cis rs514406 0.505 rs431459 chr1:53183230 T/G cg01802117 chr1:53393560 SCP2 -0.39 -4.61 -0.38 9.88e-6 Monocyte count; TGCT cis rs9291683 0.610 rs993173 chr4:10323935 T/C cg00071950 chr4:10020882 SLC2A9 -0.46 -4.92 -0.4 2.74e-6 Bone mineral density; TGCT trans rs2727020 0.729 rs588458 chr11:49214048 C/A cg15704280 chr7:45808275 SEPT13 0.64 6.81 0.52 3.74e-10 Coronary artery disease; TGCT cis rs4936891 0.645 rs74858431 chr11:123902862 T/C cg22125253 chr11:123886957 OR10G4 0.21 4.83 0.4 3.98e-6 Male fertility; TGCT cis rs9902453 0.967 rs28792710 chr17:28450015 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs886126 0.585 rs7295764 chr12:111693198 G/A cg10833066 chr12:111807467 FAM109A 0.3 4.48 0.37 1.68e-5 Coronary heart disease; TGCT cis rs8177253 0.965 rs7638018 chr3:133495461 C/T cg16414030 chr3:133502952 NA 0.6 9.8 0.66 3.77e-17 Iron status biomarkers; TGCT cis rs7572733 0.515 rs6726506 chr2:198846486 G/T cg00792783 chr2:198669748 PLCL1 0.57 5.1 0.42 1.24e-6 Dermatomyositis; TGCT cis rs7226408 0.948 rs72883572 chr18:34382334 T/A cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs514406 0.763 rs6685599 chr1:53213172 G/A cg08859206 chr1:53392774 SCP2 0.4 5.88 0.47 3.56e-8 Monocyte count; TGCT cis rs9611565 0.649 rs2413659 chr22:42164862 A/G cg06481639 chr22:41940642 POLR3H 0.54 4.55 0.38 1.25e-5 Vitiligo; TGCT cis rs9457247 1.000 rs413232 chr6:167400972 G/A cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs9913156 0.696 rs72835620 chr17:4558128 G/A cg23387401 chr17:4582204 PELP1 0.31 4.57 0.38 1.14e-5 Lymphocyte counts; TGCT cis rs62244186 0.566 rs3762636 chr3:44854563 A/G cg04389838 chr3:44770851 ZNF501 -0.36 -4.72 -0.39 6.2e-6 Depressive symptoms; TGCT cis rs13392177 0.684 rs11682371 chr2:219079513 G/A cg00012203 chr2:219082015 ARPC2 -0.79 -8.02 -0.58 6.73e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs35306767 0.903 rs35567307 chr10:915804 G/C cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs896854 0.654 rs16893776 chr8:95973604 C/T cg13393036 chr8:95962371 TP53INP1 -0.62 -8.41 -0.6 8.05e-14 Type 2 diabetes; TGCT cis rs1467026 0.589 rs9876483 chr3:12803792 G/T cg05775895 chr3:12838266 CAND2 0.53 5.32 0.43 4.61e-7 P wave duration; TGCT cis rs2290402 0.536 rs56223707 chr4:881896 C/T cg23332689 chr4:987652 IDUA;SLC26A1 0.33 5.0 0.41 1.94e-6 Type 2 diabetes; TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.71 -0.39 6.54e-6 Prudent dietary pattern; TGCT cis rs3784262 0.765 rs8026952 chr15:58276950 C/A cg12031962 chr15:58353849 ALDH1A2 -0.42 -5.94 -0.47 2.69e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs8031584 0.958 rs7168641 chr15:31235452 G/A cg08704250 chr15:31115839 NA -0.36 -4.96 -0.41 2.28e-6 Huntington's disease progression; TGCT cis rs6484504 0.576 rs11031320 chr11:31242545 C/T cg26647111 chr11:31128758 NA -0.34 -4.73 -0.39 5.88e-6 Red blood cell count; TGCT cis rs6951245 1.000 rs1881123 chr7:1084706 C/T cg27454412 chr7:1067447 C7orf50 0.57 4.48 0.37 1.71e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs17443541 0.507 rs4675698 chr2:200451350 T/C cg00055341 chr2:200446845 NA -0.31 -4.45 -0.37 1.89e-5 Intelligence (multi-trait analysis); TGCT cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.71 5.14 0.42 1.02e-6 Platelet count; TGCT cis rs3751972 0.681 rs986993 chr17:26187576 A/G cg02948944 chr17:26242737 NA 0.38 5.17 0.42 9.01e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs3087591 0.959 rs9893872 chr17:29571195 G/A cg24425628 chr17:29625626 OMG;NF1 -0.48 -7.48 -0.56 1.18e-11 Hip circumference; TGCT cis rs2455799 0.559 rs1584325 chr3:15903888 G/T cg12172478 chr3:16357591 RFTN1 -0.36 -5.3 -0.43 5.07e-7 Mean platelet volume; TGCT cis rs769267 0.896 rs2074298 chr19:19377716 C/G cg19010396 chr19:19431384 KIAA0892;SF4 0.54 4.47 0.37 1.77e-5 Tonsillectomy; TGCT cis rs11264213 0.901 rs67641270 chr1:36413329 T/C cg07093915 chr1:36184400 C1orf216 0.65 4.47 0.37 1.77e-5 Schizophrenia; TGCT cis rs55883249 1.000 rs62119428 chr2:9743332 T/C cg23886495 chr2:9695866 ADAM17 0.81 5.0 0.41 1.93e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs709400 1.000 rs861539 chr14:104165753 G/A cg26031613 chr14:104095156 KLC1 1.13 16.87 0.83 6.66e-34 Body mass index; TGCT cis rs9393777 0.513 rs3999471 chr6:26650306 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.59 -4.66 -0.39 8.03e-6 Intelligence (multi-trait analysis); TGCT cis rs7611238 0.560 rs9854941 chr3:195066926 G/A cg27323046 chr3:195102265 ACAP2 0.35 4.82 0.4 4.11e-6 Body mass index; TGCT cis rs7772486 0.875 rs2814876 chr6:146304030 C/T cg13319975 chr6:146136371 FBXO30 -0.52 -4.62 -0.38 9.45e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7809950 1.000 rs12667527 chr7:107086969 T/C cg23024343 chr7:107201750 COG5 -0.35 -5.42 -0.44 2.97e-7 Coronary artery disease; TGCT cis rs473651 0.904 rs62196716 chr2:239356977 C/G cg18131467 chr2:239335373 ASB1 1.01 14.86 0.8 2.56e-29 Multiple system atrophy; TGCT cis rs797680 0.930 rs11164870 chr1:93552187 C/G cg17826107 chr1:92977322 EVI5 -0.2 -4.62 -0.38 9.6e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs4808199 0.948 rs11085261 chr19:19462606 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.64 4.75 0.39 5.58e-6 Nonalcoholic fatty liver disease; TGCT cis rs9325144 0.624 rs10506126 chr12:39123244 G/A cg26384229 chr12:38710491 ALG10B -0.62 -5.82 -0.46 4.71e-8 Morning vs. evening chronotype; TGCT cis rs478304 0.637 rs11227255 chr11:65454044 C/T cg17480646 chr11:65405466 SIPA1 -0.63 -8.47 -0.61 6.08e-14 Acne (severe); TGCT cis rs4927850 1.000 rs10881564 chr3:195750326 C/T cg02975922 chr3:195473998 MUC4 -0.24 -5.44 -0.44 2.69e-7 Pancreatic cancer; TGCT cis rs319204 1.000 rs319238 chr5:146240381 G/A cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs6089584 0.566 rs7274240 chr20:60622004 C/T cg13770153 chr20:60521292 NA -0.39 -4.65 -0.39 8.39e-6 Body mass index; TGCT cis rs2456568 0.867 rs10501810 chr11:93666589 C/G cg16099599 chr11:93583650 C11orf90 -0.4 -4.78 -0.39 4.88e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7618915 0.501 rs3774366 chr3:52641255 T/C cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.22e-17 Bipolar disorder; TGCT cis rs2594989 0.780 rs2443706 chr3:11550505 C/G cg00170343 chr3:11313890 ATG7 0.64 4.67 0.39 7.71e-6 Circulating chemerin levels; TGCT cis rs11098499 0.532 rs4504231 chr4:120586891 G/A cg09307838 chr4:120376055 NA 0.62 5.92 0.47 2.89e-8 Corneal astigmatism; TGCT cis rs10488031 0.557 rs34553617 chr7:37101129 G/A cg06458904 chr7:36312573 EEPD1 0.58 4.79 0.39 4.72e-6 QT interval; TGCT cis rs10791097 0.668 rs10791102 chr11:130744977 G/A cg14779329 chr11:130786720 SNX19 0.28 4.82 0.4 4.09e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs3749237 0.595 rs11720264 chr3:49580347 C/T cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs60843830 1.000 rs6709534 chr2:217334 G/C cg25945732 chr2:264204 ACP1;SH3YL1 0.76 7.21 0.54 4.93e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1483890 0.723 rs1843046 chr3:69410614 C/A cg22125112 chr3:69402811 FRMD4B 0.29 4.74 0.39 5.85e-6 Resting heart rate; TGCT cis rs1008375 0.898 rs2079892 chr4:17577163 G/A cg10189774 chr4:17578691 LAP3 0.64 5.61 0.45 1.28e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7258465 1.000 rs7252707 chr19:18612257 G/A cg06462663 chr19:18546047 ISYNA1 0.21 4.66 0.39 8.13e-6 Breast cancer; TGCT cis rs9788333 0.707 rs12584557 chr13:21886171 C/A cg04632378 chr13:21900426 NA 0.4 4.92 0.4 2.68e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT cis rs12477438 0.501 rs13033012 chr2:99795149 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.05 14.89 0.8 2.21e-29 Chronic sinus infection; TGCT trans rs2688608 0.780 rs2688619 chr10:75682176 A/G cg13918328 chr10:52500089 ASAH2B 0.68 6.93 0.53 1.99e-10 Inflammatory bowel disease; TGCT cis rs7582180 0.663 rs4850929 chr2:100990707 A/C cg08017756 chr2:100939284 LONRF2 -0.31 -5.14 -0.42 1.06e-6 Intelligence (multi-trait analysis); TGCT cis rs7428 0.527 rs4832164 chr2:85546932 A/C cg24342717 chr2:85555507 TGOLN2 -0.49 -8.0 -0.58 7.48e-13 Ear protrusion; TGCT cis rs4700695 0.719 rs40176 chr5:65464965 C/T cg21114390 chr5:65439923 SFRS12 -0.82 -6.8 -0.52 4.03e-10 Facial morphology (factor 19); TGCT cis rs9611565 0.512 rs9611672 chr22:42209922 A/G cg06634786 chr22:41940651 POLR3H -0.86 -8.01 -0.58 7.16e-13 Vitiligo; TGCT cis rs6835098 1.000 rs1054496 chr4:174089080 A/G cg08422745 chr4:174089978 GALNT7 -0.94 -10.98 -0.7 5.25e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs1541995 0.824 rs2397829 chr15:96245270 C/T cg00882281 chr15:96346592 NA 0.3 4.85 0.4 3.7e-6 Photic sneeze reflex; TGCT cis rs7568458 0.783 rs1561198 chr2:85809989 C/T cg02493740 chr2:85810744 VAMP5 -0.34 -6.24 -0.49 6.43e-9 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2228638 0.816 rs2269093 chr10:33528772 A/G cg08604594 chr10:33798231 NA -0.4 -4.8 -0.4 4.55e-6 Tetralogy of Fallot; TGCT cis rs2180341 0.814 rs9321085 chr6:127735361 T/C cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs951366 0.617 rs823074 chr1:205774839 T/C cg14159672 chr1:205819179 PM20D1 0.72 10.27 0.68 2.85e-18 Menarche (age at onset); TGCT cis rs4888262 0.526 rs13330282 chr16:74572373 C/T cg01733217 chr16:74700730 RFWD3 0.71 7.11 0.54 8.09e-11 Testicular germ cell tumor; TGCT cis rs6952808 0.692 rs56727870 chr7:2029940 T/C cg04267008 chr7:1944627 MAD1L1 -0.41 -5.45 -0.44 2.65e-7 Bipolar disorder and schizophrenia; TGCT cis rs9733 0.519 rs1134067 chr1:150721175 G/T cg04414720 chr1:150670196 GOLPH3L 0.4 5.21 0.42 7.77e-7 Tonsillectomy; TGCT cis rs1670533 0.932 rs935968 chr4:1063187 G/T cg20887711 chr4:1340912 KIAA1530 0.7 5.58 0.45 1.45e-7 Recombination rate (females); TGCT cis rs6450176 0.625 rs67656636 chr5:53288455 C/A ch.5.1024479R chr5:53302184 ARL15 -0.69 -5.58 -0.45 1.45e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs12497850 0.931 rs62262517 chr3:49134914 T/G cg07636037 chr3:49044803 WDR6 0.97 10.64 0.69 3.45e-19 Parkinson's disease; TGCT cis rs75686122 0.892 rs77475063 chr8:104586060 T/A cg04852977 chr8:104510831 NA 0.59 4.45 0.37 1.92e-5 Cocaine dependence; TGCT trans rs208520 1.000 rs12216109 chr6:66987488 C/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.83 7.46 0.56 1.31e-11 Exhaled nitric oxide output; TGCT cis rs1997103 0.954 rs1997099 chr7:55405540 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs911263 0.603 rs12878627 chr14:68795149 G/A cg18825221 chr14:68749962 RAD51L1 0.22 4.46 0.37 1.82e-5 Primary biliary cholangitis; TGCT cis rs769267 0.930 rs4808959 chr19:19572108 T/G cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.72 0.46 7.46e-8 Tonsillectomy; TGCT cis rs1862618 0.573 rs1550821 chr5:56242323 C/T cg20203395 chr5:56204925 C5orf35 0.79 6.24 0.49 6.41e-9 Initial pursuit acceleration; TGCT cis rs4252435 0.614 rs56874942 chr7:142600954 A/T cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs2204008 0.583 rs12820907 chr12:37990931 T/C cg13010199 chr12:38710504 ALG10B 0.61 4.89 0.4 3.05e-6 Bladder cancer; TGCT cis rs12579753 0.879 rs11115002 chr12:82153090 C/T cg21231944 chr12:82153410 PPFIA2 -0.35 -4.61 -0.38 9.96e-6 Resting heart rate; TGCT trans rs9383153 1.000 rs9370888 chr6:16335544 A/G cg18843856 chr2:121651050 GLI2 0.83 6.66 0.51 7.84e-10 Gambling; TGCT cis rs9905704 0.647 rs12943705 chr17:57097047 T/C cg05425664 chr17:57184151 TRIM37 0.68 5.61 0.45 1.25e-7 Testicular germ cell tumor; TGCT cis rs10782582 0.609 rs1001160 chr1:76358591 A/C cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.54 0.38 1.31e-5 Daytime sleep phenotypes; TGCT cis rs5750830 0.649 rs4821893 chr22:39797779 G/A cg01416388 chr22:39784598 NA -0.72 -7.15 -0.54 6.43e-11 Intelligence (multi-trait analysis); TGCT cis rs2677744 0.962 rs1266486 chr15:91460284 T/C cg22570213 chr15:91497863 RCCD1 0.37 4.5 0.37 1.54e-5 Attention deficit hyperactivity disorder; TGCT cis rs6089584 0.816 rs6061410 chr20:60625329 A/G cg13770153 chr20:60521292 NA -0.62 -7.94 -0.58 1.02e-12 Body mass index; TGCT cis rs9311474 0.607 rs13076398 chr3:52573096 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 4.97e-10 Electroencephalogram traits; TGCT trans rs225245 0.541 rs321613 chr17:33881718 G/A cg19694781 chr19:47549865 TMEM160 -0.36 -6.69 -0.51 6.94e-10 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs7829975 0.514 rs2976929 chr8:8258712 T/C cg15556689 chr8:8085844 FLJ10661 0.73 6.64 0.51 8.65e-10 Mood instability; TGCT cis rs9911578 1.000 rs2643119 chr17:56827760 G/T cg12560992 chr17:57184187 TRIM37 0.76 9.34 0.64 4.88e-16 Intelligence (multi-trait analysis); TGCT trans rs1005277 0.579 rs2472176 chr10:38382921 T/C cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.13e-14 Extrinsic epigenetic age acceleration; TGCT cis rs1862618 0.525 rs2662019 chr5:56263104 A/G cg12311346 chr5:56204834 C5orf35 0.6 5.39 0.44 3.46e-7 Initial pursuit acceleration; TGCT cis rs12701220 0.725 rs13242971 chr7:1055515 C/T cg07217954 chr7:1067459 C7orf50 -0.49 -4.83 -0.4 3.96e-6 Bronchopulmonary dysplasia; TGCT cis rs7091068 0.616 rs1409336 chr10:95479674 T/G cg20715218 chr10:95462985 C10orf4 0.56 5.29 0.43 5.36e-7 Urinary tract infection frequency; TGCT cis rs4862307 0.836 rs4643860 chr4:184997945 T/C cg06737308 chr4:185021514 ENPP6 -0.33 -4.78 -0.39 4.92e-6 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs6121246 0.609 rs6060843 chr20:30297047 G/C cg13852791 chr20:30311386 BCL2L1 0.77 7.0 0.53 1.44e-10 Mean corpuscular hemoglobin; TGCT cis rs7246657 0.722 rs8110865 chr19:38047387 G/A cg18154014 chr19:37997991 ZNF793 0.69 4.63 0.38 9.25e-6 Coronary artery calcification; TGCT cis rs12541335 0.590 rs11136002 chr8:22217082 C/T cg02788857 chr8:22132959 PIWIL2 0.29 5.14 0.42 1.04e-6 Hypertriglyceridemia; TGCT cis rs2066819 0.818 rs703830 chr12:56701872 T/C cg26714650 chr12:56694279 CS 1.53 8.28 0.6 1.67e-13 Psoriasis vulgaris; TGCT cis rs12984174 1.000 rs403439 chr19:18142075 A/G cg21649277 chr19:18117794 ARRDC2 -0.71 -4.64 -0.38 8.84e-6 Pulmonary function in asthmatics; TGCT cis rs17401966 0.540 rs11121557 chr1:10448260 T/G cg19773385 chr1:10388646 KIF1B -0.22 -5.27 -0.43 5.96e-7 Hepatocellular carcinoma; TGCT cis rs7618915 0.501 rs3755798 chr3:52741160 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs4665809 0.590 rs7604564 chr2:26501953 C/A cg25036284 chr2:26402008 FAM59B 0.65 5.18 0.42 8.59e-7 Gut microbiome composition (summer); TGCT cis rs597539 0.652 rs636049 chr11:68667198 A/C cg06112835 chr11:68658793 MRPL21 0.47 8.32 0.6 1.32e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9467711 0.559 rs2295593 chr6:26501768 C/T cg16898833 chr6:26189333 HIST1H4D 1.01 5.1 0.42 1.21e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs1129187 0.782 rs9462860 chr6:42947013 G/C cg27588902 chr6:42928151 GNMT -0.57 -7.0 -0.53 1.39e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs9513593 1.000 rs7331894 chr13:99852952 C/T cg21788972 chr13:99853209 UBAC2 0.61 4.96 0.41 2.24e-6 Psoriasis; TGCT cis rs2439831 1.000 rs2467740 chr15:43746792 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.37 0.6 1.02e-13 Lung cancer in ever smokers; TGCT cis rs6741892 0.536 rs13024840 chr2:38895920 T/A cg08308459 chr2:38893161 GALM -0.7 -4.61 -0.38 9.7e-6 5-HTT brain serotonin transporter levels; TGCT cis rs5769765 0.955 rs9616367 chr22:50303515 A/C cg22709217 chr22:50311962 ALG12;CRELD2 -1.17 -11.76 -0.73 6.61e-22 Schizophrenia; TGCT cis rs7267979 0.966 rs6107031 chr20:25350677 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.570 rs11714088 chr3:52758942 A/C cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs4808199 0.948 rs757001 chr19:19448808 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.33 0.43 4.49e-7 Nonalcoholic fatty liver disease; TGCT cis rs9611565 0.592 rs4822044 chr22:41979668 G/C cg03806693 chr22:41940476 POLR3H -1.1 -11.57 -0.72 1.86e-21 Vitiligo; TGCT cis rs3796352 1.000 rs116616340 chr3:53132371 C/G cg27565382 chr3:53032988 SFMBT1 0.4 4.44 0.37 1.94e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs968567 0.528 rs174582 chr11:61607168 A/G cg19610905 chr11:61596333 FADS2 -0.89 -6.8 -0.52 3.93e-10 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs6671200 0.688 rs4950024 chr1:95713499 A/G cg06440946 chr1:95699313 RWDD3 -0.62 -5.3 -0.43 5.09e-7 Stearic acid (18:0) levels; TGCT cis rs6938 0.597 rs11856413 chr15:75199892 A/G cg09165964 chr15:75287851 SCAMP5 0.57 5.36 0.43 3.86e-7 Breast cancer; TGCT cis rs8072100 0.935 rs8070759 chr17:45638760 C/T cg08085267 chr17:45401833 C17orf57 0.42 4.6 0.38 1.01e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs11779988 0.545 rs415840 chr8:17782134 C/T cg01800426 chr8:17659068 MTUS1 -0.67 -5.19 -0.42 8.49e-7 Breast cancer; TGCT cis rs2050392 0.928 rs2250077 chr10:30702929 A/G cg13289132 chr10:30722225 MAP3K8 -0.36 -4.47 -0.37 1.72e-5 Inflammatory bowel disease; TGCT cis rs1799949 1.000 rs9646417 chr17:41424253 G/A cg10047753 chr17:41438598 NA 0.95 9.61 0.65 1.12e-16 Menopause (age at onset); TGCT cis rs7909074 0.831 rs11239271 chr10:45376294 A/G cg04218760 chr10:45406644 TMEM72 -0.31 -5.95 -0.47 2.52e-8 Mean corpuscular volume; TGCT cis rs2235642 0.928 rs56289115 chr16:1608934 A/G cg00463982 chr16:1583984 IFT140;TMEM204 -0.28 -4.79 -0.4 4.64e-6 Coronary artery disease; TGCT cis rs2243480 1.000 rs906134 chr7:65444288 G/C cg20637647 chr7:64974828 NA 0.97 5.37 0.43 3.82e-7 Diabetic kidney disease; TGCT cis rs6952808 0.575 rs10280993 chr7:1948096 T/C cg22963979 chr7:1858916 MAD1L1 -0.37 -5.62 -0.45 1.22e-7 Bipolar disorder and schizophrenia; TGCT cis rs7666738 0.830 rs6831925 chr4:98947401 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.943 rs28660238 chr7:100023308 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs7647973 0.961 rs11130187 chr3:49307872 T/C cg05785598 chr3:49045655 WDR6 0.39 4.61 0.38 9.91e-6 Menarche (age at onset); TGCT cis rs853679 0.550 rs1233699 chr6:28169158 A/T cg12963246 chr6:28129442 ZNF389 0.48 4.85 0.4 3.66e-6 Depression; TGCT trans rs1005277 0.579 rs2505241 chr10:38442421 T/C cg27523141 chr10:43048294 ZNF37B 0.74 8.58 0.61 3.28e-14 Extrinsic epigenetic age acceleration; TGCT cis rs4843185 0.731 rs10514608 chr16:85713173 C/G cg07795346 chr16:84800637 USP10 0.23 4.54 0.38 1.31e-5 Platelet distribution width; TGCT cis rs13064411 0.696 rs1552432 chr3:113225660 G/C cg18753928 chr3:113234510 CCDC52 -0.71 -5.78 -0.46 5.63e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs67311347 1.000 rs951560 chr3:40463471 A/G cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs10504229 1.000 rs73609760 chr8:58192170 A/G cg20607798 chr8:58055168 NA 0.45 4.62 0.38 9.32e-6 Developmental language disorder (linguistic errors); TGCT trans rs877282 0.945 rs11253390 chr10:788678 A/G cg22713356 chr15:30763199 NA 1.16 10.26 0.68 3.01e-18 Uric acid levels; TGCT cis rs727505 0.721 rs67277928 chr7:124776704 G/T cg23710748 chr7:124431027 NA -0.25 -4.63 -0.38 9.13e-6 Lewy body disease; TGCT cis rs79387448 0.592 rs76362690 chr2:102951477 A/G cg09003973 chr2:102972529 NA 1.4 9.44 0.65 2.87e-16 Gut microbiota (bacterial taxa); TGCT cis rs9916302 0.904 rs7223331 chr17:37482930 A/G cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs3733585 0.657 rs62286568 chr4:10124889 C/T cg11266682 chr4:10021025 SLC2A9 -0.51 -5.88 -0.47 3.61e-8 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs28830936 0.509 rs6493004 chr15:41858687 A/G cg17847044 chr15:42102381 MAPKBP1 0.19 4.71 0.39 6.42e-6 Diastolic blood pressure; TGCT cis rs875971 1.000 rs11971949 chr7:65626014 A/G cg11764359 chr7:65958608 NA -0.6 -5.32 -0.43 4.63e-7 Aortic root size; TGCT trans rs3808502 0.503 rs2061830 chr8:11397457 C/G cg06636001 chr8:8085503 FLJ10661 0.72 6.86 0.52 2.86e-10 Neuroticism; TGCT cis rs10479542 0.583 rs4131080 chr5:179044292 G/A cg14820908 chr5:178986412 RUFY1 0.59 6.22 0.49 6.87e-9 Lung cancer; TGCT cis rs1552244 0.554 rs6800204 chr3:9995404 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 -0.32 -4.84 -0.4 3.76e-6 Alzheimer's disease; TGCT cis rs909674 0.541 rs5750816 chr22:39810379 A/G cg02038168 chr22:39784481 NA 0.77 6.61 0.51 1.02e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs9611565 0.559 rs6002408 chr22:41967870 C/T cg17554472 chr22:41940697 POLR3H -0.49 -5.08 -0.41 1.36e-6 Vitiligo; TGCT cis rs9811920 0.609 rs9872871 chr3:99658702 C/G cg07805332 chr3:99536008 MIR548G;C3orf26 0.59 6.77 0.52 4.51e-10 Axial length; TGCT cis rs1552244 1.000 rs6786638 chr3:10118075 G/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.45 -0.5 2.31e-9 Alzheimer's disease; TGCT cis rs9517320 0.515 rs9556969 chr13:99195948 T/C cg07423050 chr13:99094983 FARP1 -0.28 -5.44 -0.44 2.76e-7 Longevity; TGCT cis rs244731 1.000 rs244731 chr5:176539679 C/T cg17509989 chr5:176798049 RGS14 0.55 6.52 0.51 1.6e-9 Urate levels in lean individuals; TGCT cis rs9357506 0.875 rs9395175 chr6:46315337 A/T cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs6964587 1.000 rs6946356 chr7:91727385 G/A cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs11252926 0.507 rs4881199 chr10:428090 C/G cg13477178 chr10:375248 DIP2C -0.26 -5.03 -0.41 1.65e-6 Psychosis in Alzheimer's disease; TGCT cis rs9788682 0.948 rs59133824 chr15:78833450 C/A cg06917634 chr15:78832804 PSMA4 -0.7 -4.86 -0.4 3.47e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT trans rs916888 0.821 rs199525 chr17:44847834 T/G cg01341218 chr17:43662625 NA 1.09 9.23 0.64 9.27e-16 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs709400 0.663 rs2273703 chr14:103918029 C/G cg26031613 chr14:104095156 KLC1 0.83 9.07 0.63 2.22e-15 Body mass index; TGCT cis rs1218582 0.772 rs4240875 chr1:154885782 G/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs9902453 0.967 rs4533341 chr17:28495672 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs9926296 0.605 rs6500453 chr16:89858657 C/G cg27121462 chr16:89883253 FANCA 0.81 9.17 0.64 1.26e-15 Vitiligo; TGCT cis rs3020736 0.500 rs5996110 chr22:42493767 A/G cg15557168 chr22:42548783 NA 0.22 5.58 0.45 1.47e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs17152411 0.901 rs7081640 chr10:126592522 C/T cg07906193 chr10:126599966 NA 0.32 4.59 0.38 1.09e-5 Height; TGCT cis rs9467711 0.606 rs9358939 chr6:26416787 C/G cg10795676 chr6:26370623 BTN3A2 -0.45 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9814567 0.806 rs4074521 chr3:134325536 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.78 7.26 0.55 3.68e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2933343 0.601 rs1680759 chr3:128594896 C/G cg11901034 chr3:128598214 ACAD9 -0.66 -6.11 -0.48 1.2e-8 IgG glycosylation; TGCT cis rs1062177 0.855 rs6892117 chr5:151264985 C/T cg00977110 chr5:151150581 G3BP1 -0.39 -4.45 -0.37 1.87e-5 Preschool internalizing problems; TGCT cis rs4455778 0.659 rs13237643 chr7:49025116 C/T cg26309511 chr7:48887640 NA -0.45 -5.25 -0.43 6.39e-7 Lung cancer in never smokers; TGCT cis rs62209 0.800 rs201078 chr10:11002752 A/G cg26901096 chr10:10994189 LOC254312 0.28 4.77 0.39 5.12e-6 Alzheimer's disease (late onset); TGCT cis rs875971 0.660 rs801190 chr7:66033033 C/T cg18876405 chr7:65276391 NA -0.37 -5.58 -0.45 1.47e-7 Aortic root size; TGCT cis rs7586879 1.000 rs6736711 chr2:25116456 C/T cg01884057 chr2:25150051 NA 0.28 5.03 0.41 1.69e-6 Body mass index; TGCT cis rs7843479 0.965 rs1484162 chr8:21831385 A/G cg17168535 chr8:21777572 XPO7 0.63 5.72 0.46 7.3900000000000007e-08 Mean corpuscular volume; TGCT cis rs6570726 0.791 rs7765675 chr6:145915077 A/C cg23711669 chr6:146136114 FBXO30 0.89 9.62 0.65 1.06e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6669072 0.703 rs3843306 chr1:91288130 A/T cg08895590 chr1:91227319 NA 0.4 5.11 0.42 1.19e-6 Cognitive function; TGCT cis rs6722750 1.000 rs12475563 chr2:64384515 G/A cg22352474 chr2:64371530 PELI1 0.6 5.26 0.43 6.15e-7 Neuroticism; TGCT cis rs4808199 0.948 rs12982276 chr19:19459800 T/C cg02546618 chr19:19431379 KIAA0892;SF4 0.65 4.91 0.4 2.77e-6 Nonalcoholic fatty liver disease; TGCT cis rs3796352 1.000 rs34313969 chr3:52995166 A/G cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3806843 0.868 rs2262573 chr5:140123627 T/A cg19875535 chr5:140030758 IK -0.35 -5.92 -0.47 2.89e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2346177 0.875 rs2881327 chr2:46641955 A/G cg26688816 chr2:46740690 ATP6V1E2 -0.43 -4.84 -0.4 3.73e-6 HDL cholesterol; TGCT cis rs12989701 0.825 rs4663097 chr2:127861906 C/G cg08168897 chr2:127865431 BIN1 -0.52 -6.32 -0.49 4.3e-9 Alzheimer's disease (late onset); TGCT cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg13409248 chr3:40428643 ENTPD3 0.57 4.53 0.38 1.37e-5 Renal cell carcinoma; TGCT cis rs12579753 0.833 rs1922566 chr12:82135030 T/C cg21231944 chr12:82153410 PPFIA2 -0.36 -4.7 -0.39 6.72e-6 Resting heart rate; TGCT cis rs6570726 0.557 rs403956 chr6:145829956 T/C cg23711669 chr6:146136114 FBXO30 0.71 6.51 0.5 1.72e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.03 0.53 1.23e-10 Prudent dietary pattern; TGCT cis rs2180341 0.711 rs4371861 chr6:127568447 G/T cg24812749 chr6:127587940 RNF146 0.65 5.96 0.47 2.45e-8 Breast cancer; TGCT cis rs7909074 0.966 rs4268464 chr10:45401081 T/A cg05187965 chr10:45406764 TMEM72 -0.23 -4.88 -0.4 3.25e-6 Mean corpuscular volume; TGCT cis rs7666738 0.830 rs10009206 chr4:99056900 A/C cg17366294 chr4:99064904 C4orf37 -0.72 -7.45 -0.56 1.39e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs74233809 1.000 rs10883808 chr10:104721126 A/T cg05855489 chr10:104503620 C10orf26 0.74 4.45 0.37 1.87e-5 Birth weight; TGCT cis rs6500602 0.609 rs7202910 chr16:4518948 T/A cg06139259 chr16:4526053 HMOX2;NMRAL1 0.27 4.87 0.4 3.38e-6 Schizophrenia; TGCT cis rs10504229 0.906 rs58251024 chr8:58172259 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs9549367 0.756 rs9549702 chr13:113881944 T/G cg00898013 chr13:113819073 PROZ -0.41 -5.21 -0.42 7.7300000000000005e-07 Platelet distribution width; TGCT cis rs2549003 1.000 rs2070731 chr5:131819798 T/C cg21138405 chr5:131827807 IRF1 0.18 4.71 0.39 6.49e-6 Asthma (sex interaction); TGCT cis rs4713118 0.615 rs9348772 chr6:27656090 G/T cg10876282 chr6:28092338 ZSCAN16 0.51 5.19 0.42 8.45e-7 Parkinson's disease; TGCT cis rs6840360 0.571 rs4696275 chr4:152530981 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs6725041 0.819 rs10172865 chr2:213089339 G/A cg20637307 chr2:213403960 ERBB4 -0.52 -4.47 -0.37 1.72e-5 QT interval (ambient particulate matter interaction); TGCT cis rs17331151 0.573 rs2276818 chr3:52864635 A/G cg11137980 chr3:52469226 SEMA3G 0.29 5.14 0.42 1.04e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs78487399 0.808 rs6757251 chr2:43734847 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.79 -0.4 4.67e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2153535 0.580 rs9393022 chr6:8466588 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg27286337 chr10:134555280 INPP5A 0.38 4.57 0.38 1.17e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4808199 0.947 rs2099333 chr19:19605963 C/T cg03709012 chr19:19516395 GATAD2A 1.0 7.8 0.57 2.23e-12 Nonalcoholic fatty liver disease; TGCT trans rs551517 0.541 rs576559 chr9:113642646 T/C cg18410444 chr5:89825535 LYSMD3 0.66 6.73 0.52 5.51e-10 Post bronchodilator FEV1 in COPD;Sum eosinophil basophil counts;Eosinophil percentage of white cells; TGCT cis rs6121246 0.559 rs6087782 chr20:30391580 C/T cg13852791 chr20:30311386 BCL2L1 0.8 7.42 0.55 1.61e-11 Mean corpuscular hemoglobin; TGCT cis rs9611565 0.921 rs5751080 chr22:41736267 A/G cg06634786 chr22:41940651 POLR3H -0.63 -6.01 -0.47 1.93e-8 Vitiligo; TGCT cis rs1107366 0.513 rs10934761 chr3:125973585 G/T cg01346077 chr3:125931526 NA 0.32 5.3 0.43 5.03e-7 Metabolite levels; TGCT cis rs12971120 1.000 rs12971120 chr18:72174023 A/G cg25817165 chr18:72167213 CNDP2 -0.25 -4.5 -0.37 1.56e-5 Refractive error; TGCT cis rs11209002 0.571 rs7531772 chr1:67555516 T/C cg02640540 chr1:67518911 SLC35D1 0.56 4.66 0.39 8.05e-6 Crohn's disease; TGCT cis rs7786808 0.653 rs7810861 chr7:158212633 G/A cg01191920 chr7:158217561 PTPRN2 -0.38 -6.01 -0.48 1.88e-8 Obesity-related traits; TGCT cis rs67311347 1.000 rs9332450 chr3:40458041 C/T cg13683864 chr3:40499215 RPL14 1.04 10.79 0.7 1.54e-19 Renal cell carcinoma; TGCT trans rs916888 0.773 rs169201 chr17:44790203 A/G cg07870213 chr5:140052090 DND1 0.67 7.91 0.58 1.22e-12 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs778371 0.676 rs13024330 chr2:233715487 A/G cg08000102 chr2:233561755 GIGYF2 0.67 7.67 0.57 4.47e-12 Schizophrenia; TGCT cis rs6558174 0.965 rs2404655 chr8:22490209 T/C cg03733263 chr8:22462867 KIAA1967 0.68 5.47 0.44 2.42e-7 Breast cancer; TGCT cis rs11247915 0.600 rs11247920 chr1:26665478 C/T cg01414934 chr1:26605969 SH3BGRL3 0.21 4.51 0.38 1.46e-5 Obesity-related traits; TGCT cis rs79387448 0.505 rs17027327 chr2:103122513 C/A cg09003973 chr2:102972529 NA 0.85 5.65 0.45 1.03e-7 Gut microbiota (bacterial taxa); TGCT cis rs1862618 0.671 rs2255726 chr5:56243128 T/C cg24531977 chr5:56204891 C5orf35 0.68 7.14 0.54 6.98e-11 Initial pursuit acceleration; TGCT cis rs12049351 0.774 rs6671385 chr1:229642652 C/T cg12130225 chr1:229698885 NA 0.39 4.6 0.38 1.02e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs250677 0.687 rs250663 chr5:148453117 T/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs3771570 1.000 rs59496049 chr2:242260756 G/C cg21155796 chr2:242212141 HDLBP 0.93 6.82 0.52 3.63e-10 Prostate cancer; TGCT cis rs270601 0.661 rs10036208 chr5:131571323 T/C cg12564285 chr5:131593104 PDLIM4 0.37 4.44 0.37 1.98e-5 Acylcarnitine levels; TGCT cis rs2230307 0.536 rs482466 chr1:100488177 C/T cg24955406 chr1:100503596 HIAT1 0.72 4.62 0.38 9.34e-6 Carotid intima media thickness; TGCT cis rs17384381 0.861 rs2300640 chr1:85823795 C/G cg16011679 chr1:85725395 C1orf52 0.84 6.5 0.5 1.74e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9611565 0.546 rs739129 chr22:42118249 G/A cg03806693 chr22:41940476 POLR3H 1.08 11.99 0.73 1.84e-22 Vitiligo; TGCT cis rs4295623 0.504 rs11250160 chr8:11592717 G/A cg21775007 chr8:11205619 TDH -0.54 -5.04 -0.41 1.6e-6 Morning vs. evening chronotype; TGCT cis rs12762955 0.561 rs11253567 chr10:1054444 A/G cg26597838 chr10:835615 NA 0.45 6.03 0.48 1.71e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs2228479 0.867 rs12930056 chr16:89946649 C/A cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs4929949 0.724 rs11041986 chr11:8582878 A/G cg06699848 chr11:8847662 ST5 0.28 4.45 0.37 1.89e-5 Body mass index; TGCT cis rs9372498 0.536 rs9489477 chr6:118946192 T/G cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs7402982 0.625 rs4966011 chr15:99204006 G/A cg03437748 chr15:99193247 IGF1R 0.46 4.56 0.38 1.2e-5 Birth weight; TGCT cis rs909674 0.909 rs1557541 chr22:39851970 C/A cg02038168 chr22:39784481 NA -0.7 -5.32 -0.43 4.72e-7 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10206020 0.885 rs6746052 chr2:1576811 T/C cg12573674 chr2:1569213 NA -0.46 -5.2 -0.42 7.88e-7 IgG glycosylation; TGCT cis rs10883723 0.810 rs2296581 chr10:104242886 G/A cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs7542091 0.813 rs2049999 chr1:210031331 A/G cg21951975 chr1:209979733 IRF6 0.52 5.35 0.43 4.11e-7 Monobrow; TGCT cis rs9372498 0.505 rs72956993 chr6:118949708 A/T cg21191810 chr6:118973309 C6orf204 -0.38 -4.97 -0.41 2.14e-6 Diastolic blood pressure; TGCT cis rs9549367 0.789 rs912012 chr13:113886152 G/A cg18105134 chr13:113819100 PROZ -0.34 -5.45 -0.44 2.63e-7 Platelet distribution width; TGCT cis rs3008870 0.959 rs2815359 chr1:67494374 T/C cg03991309 chr1:68237761 GNG12 0.27 4.5 0.37 1.56e-5 Lymphocyte percentage of white cells; TGCT cis rs4332037 0.539 rs55993248 chr7:2071132 A/G cg25834613 chr7:1915315 MAD1L1 -0.52 -5.11 -0.42 1.2e-6 Bipolar disorder; TGCT cis rs2033711 0.728 rs4801586 chr19:58934528 A/G cg12042659 chr19:58951599 ZNF132 0.52 4.82 0.4 4.18e-6 Uric acid clearance; TGCT cis rs13177918 0.557 rs12520101 chr5:149810923 C/T cg14059543 chr5:149831962 NA -0.69 -8.62 -0.61 2.65e-14 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs597539 0.652 rs516425 chr11:68715675 G/A cg21862992 chr11:68658383 NA 0.45 6.29 0.49 5.02e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9388451 0.839 rs4897155 chr6:126095144 C/A cg10911889 chr6:126070802 HEY2 0.54 5.64 0.45 1.09e-7 Brugada syndrome; TGCT cis rs2290402 0.536 rs73207790 chr4:865430 G/A cg23332689 chr4:987652 IDUA;SLC26A1 0.32 4.97 0.41 2.18e-6 Type 2 diabetes; TGCT cis rs2795502 1.000 rs2744092 chr10:43339343 T/C cg20628663 chr10:43360327 NA -0.44 -6.37 -0.5 3.4e-9 Blood protein levels; TGCT cis rs274567 0.711 rs404771 chr5:131635092 A/T cg24060327 chr5:131705240 SLC22A5 -0.71 -7.62 -0.56 5.58e-12 Blood metabolite levels; TGCT cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.28e-17 Electroencephalogram traits; TGCT cis rs2019137 0.560 rs10175462 chr2:113988492 G/A cg17445212 chr2:113993313 PAX8;LOC440839;LOC654433 0.46 4.86 0.4 3.51e-6 Lymphocyte counts; TGCT trans rs7618501 0.933 rs6809431 chr3:49804119 A/G cg21665057 chr3:196295764 WDR53;FBXO45 1.03 13.16 0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs1371867 0.846 rs1660349 chr8:101319326 G/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs6701037 0.512 rs2285216 chr1:175133012 C/T cg08873628 chr1:175162347 KIAA0040 0.48 4.57 0.38 1.15e-5 Alcohol dependence; TGCT cis rs7208859 0.623 rs56095789 chr17:29060170 A/G cg14008862 chr17:28927542 LRRC37B2 0.77 4.59 0.38 1.08e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs644799 0.710 rs473852 chr11:95568757 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 7.83 0.58 1.82e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6598955 0.724 rs12754536 chr1:26639605 T/C cg04990556 chr1:26633338 UBXN11 -0.91 -11.98 -0.73 1.92e-22 Obesity-related traits; TGCT cis rs6754311 0.550 rs12994270 chr2:136518103 T/A cg07169764 chr2:136633963 MCM6 -0.66 -6.11 -0.48 1.2e-8 Mosquito bite size; TGCT cis rs9303401 0.659 rs7223708 chr17:56896398 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs28595532 0.920 rs115576008 chr4:119736967 T/C cg14228332 chr4:119757509 SEC24D 1.31 7.06 0.54 1.06e-10 Cannabis dependence symptom count; TGCT cis rs3749237 0.636 rs1568662 chr3:49521263 A/G cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs6570726 0.935 rs368848 chr6:145855281 A/T cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.800 rs4926930 chr1:53217335 A/G cg08859206 chr1:53392774 SCP2 0.4 5.88 0.47 3.56e-8 Monocyte count; TGCT cis rs6879260 1.000 rs6879260 chr5:179731014 A/G cg23221052 chr5:179740743 GFPT2 -0.35 -5.6 -0.45 1.34e-7 Height; TGCT cis rs769267 0.965 rs2905425 chr19:19475717 G/C cg20644253 chr19:19431407 KIAA0892;SF4 -0.7 -5.79 -0.46 5.35e-8 Tonsillectomy; TGCT cis rs67311347 1.000 rs7642906 chr3:40492633 G/A cg17264618 chr3:40429014 ENTPD3 -0.31 -4.52 -0.38 1.44e-5 Renal cell carcinoma; TGCT cis rs7659604 0.540 rs4833769 chr4:122672970 A/C cg19748678 chr4:122722346 EXOSC9 0.5 4.86 0.4 3.5e-6 Type 2 diabetes; TGCT cis rs3862260 0.509 rs3795663 chr1:120165187 G/A cg16322792 chr1:120165303 ZNF697 0.35 8.4 0.6 8.92e-14 Systemic lupus erythematosus; TGCT cis rs1971256 0.500 rs17081284 chr6:151800796 C/G cg14416726 chr6:151773293 C6orf211;RMND1 -0.74 -4.49 -0.37 1.63e-5 Endometriosis; TGCT trans rs7618501 0.602 rs2245365 chr3:50097319 C/A cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT trans rs7613875 0.578 rs2526749 chr3:50076734 A/G cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT cis rs6988636 1.000 rs58177772 chr8:124188067 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs7296418 0.922 rs1727293 chr12:123648032 C/T cg00376283 chr12:123451042 ABCB9 0.83 7.59 0.56 6.61e-12 Platelet count; TGCT cis rs10206020 0.921 rs72778005 chr2:1573122 C/G cg01028140 chr2:1542097 TPO -0.31 -4.77 -0.39 5.07e-6 IgG glycosylation; TGCT cis rs7584330 0.910 rs12465081 chr2:238401784 A/G cg08992911 chr2:238395768 MLPH 0.56 4.6 0.38 1.03e-5 Prostate cancer; TGCT cis rs4595586 0.545 rs12823721 chr12:39386461 G/A cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs13315871 1.000 rs71311868 chr3:58392874 A/G cg12435725 chr3:58293450 RPP14 -0.43 -4.47 -0.37 1.71e-5 Cholesterol, total; TGCT cis rs10858047 0.943 rs9729280 chr1:115076994 G/A cg12756093 chr1:115239321 AMPD1 0.45 4.64 0.38 8.87e-6 Autism; TGCT cis rs9291683 0.632 rs7679916 chr4:10042160 C/T cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.29e-14 Bone mineral density; TGCT cis rs1635 0.655 rs60698636 chr6:28316045 A/G cg15743358 chr6:28303923 ZNF323 -1.25 -6.08 -0.48 1.37e-8 Schizophrenia; TGCT trans rs2727020 0.658 rs4980431 chr11:49350071 G/T cg15704280 chr7:45808275 SEPT13 -0.69 -7.78 -0.57 2.45e-12 Coronary artery disease; TGCT trans rs208520 0.690 rs2797693 chr6:66868985 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT trans rs916888 0.821 rs70602 chr17:44859715 T/C cg22968622 chr17:43663579 NA -1.23 -10.98 -0.7 5.31e-20 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs12142240 0.698 rs79490411 chr1:46813568 G/A cg00530320 chr1:46809349 NSUN4 0.27 5.19 0.42 8.25e-7 Menopause (age at onset); TGCT cis rs28386778 0.897 rs2727287 chr17:61904728 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.07 0.82 4.16e-32 Prudent dietary pattern; TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg06873352 chr17:61820015 STRADA 0.58 6.39 0.5 3.01e-9 Prudent dietary pattern; TGCT cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs896854 0.653 rs13266313 chr8:95975302 C/T cg09323728 chr8:95962352 TP53INP1 -0.52 -6.6 -0.51 1.05e-9 Type 2 diabetes; TGCT cis rs4654899 0.580 rs1977296 chr1:21091543 G/T cg01072550 chr1:21505969 NA -0.53 -8.89 -0.62 6.03e-15 Superior frontal gyrus grey matter volume; TGCT cis rs1799949 0.526 rs4352088 chr17:41414679 A/G cg05368731 chr17:41323189 NBR1 1.16 13.44 0.77 5.72e-26 Menopause (age at onset); TGCT cis rs9322193 0.923 rs9689084 chr6:149960784 G/A cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs1451375 0.669 rs4512339 chr7:50646977 C/T cg18232548 chr7:50535776 DDC -0.46 -7.1 -0.54 8.31e-11 Malaria; TGCT cis rs870825 0.616 rs2696037 chr4:185610940 C/T cg14471096 chr4:185570637 CCDC111;CASP3 -0.67 -4.62 -0.38 9.4e-6 Blood protein levels; TGCT cis rs853679 0.517 rs35227624 chr6:28132726 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs7267979 0.668 rs4815398 chr20:25237338 C/T cg03522245 chr20:25566470 NINL -0.48 -4.58 -0.38 1.12e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7017914 0.967 rs12680988 chr8:71695890 T/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs9443189 0.570 rs7765254 chr6:76398143 T/C cg01950844 chr6:76311363 SENP6 1.01 6.27 0.49 5.46e-9 Prostate cancer; TGCT cis rs9534288 0.797 rs7331368 chr13:46609062 G/C cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs7267979 1.000 rs6050617 chr20:25421648 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2739330 0.796 rs5760097 chr22:24247794 G/C cg23131131 chr22:24373011 LOC391322 -0.8 -8.69 -0.62 1.78e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1153858 0.943 rs11070454 chr15:45680252 C/T cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7659604 0.539 rs2221628 chr4:122795361 G/A cg23574427 chr4:122746245 BBS7;CCNA2 -0.34 -5.12 -0.42 1.12e-6 Type 2 diabetes; TGCT cis rs739496 0.542 rs7300400 chr12:111792179 A/C cg10833066 chr12:111807467 FAM109A 0.44 7.52 0.56 9.58e-12 Platelet count; TGCT cis rs17331151 0.541 rs4687676 chr3:52890418 C/T cg27565382 chr3:53032988 SFMBT1 -0.46 -5.85 -0.47 4.05e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1552244 0.882 rs13075842 chr3:10055813 A/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs2115630 1.000 rs11854291 chr15:85363708 T/C cg17173187 chr15:85201210 NMB -0.4 -4.93 -0.4 2.56e-6 P wave terminal force; TGCT cis rs7552404 0.656 rs11161792 chr1:76336746 C/T cg22875332 chr1:76189707 ACADM 0.57 5.65 0.45 1.03e-7 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10089 1.000 rs1560636 chr5:127447987 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.84 8.19 0.59 2.7e-13 Ileal carcinoids; TGCT cis rs9534288 0.619 rs9526146 chr13:46680854 C/T cg15192986 chr13:46630673 CPB2 -0.5 -6.0 -0.47 2.05e-8 Blood protein levels; TGCT cis rs1878931 0.582 rs27239 chr16:3442140 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 -0.76 -6.45 -0.5 2.3e-9 Body mass index (adult); TGCT cis rs13343954 0.778 rs10426551 chr19:33541514 A/G cg07624008 chr19:33672378 NA -0.28 -4.71 -0.39 6.43e-6 Colorectal cancer; TGCT cis rs1205863 0.748 rs1205860 chr6:11943271 G/A cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs2738459 0.500 rs2738465 chr19:11242496 G/A cg13393778 chr19:10342129 S1PR2 -0.52 -4.5 -0.37 1.57e-5 LDL cholesterol; TGCT trans rs1496653 0.602 rs35209889 chr3:23517148 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs910316 1.000 rs12889309 chr14:75593902 C/T cg08847533 chr14:75593920 NEK9 0.96 10.86 0.7 1.05e-19 Height; TGCT cis rs7659604 0.539 rs7660548 chr4:122730821 G/C cg06713675 chr4:122721982 EXOSC9 -0.69 -9.69 -0.66 7.11e-17 Type 2 diabetes; TGCT cis rs9467773 0.572 rs13213953 chr6:26594534 T/A cg15659132 chr6:26577336 NA 0.84 10.07 0.67 8.62e-18 Intelligence (multi-trait analysis); TGCT cis rs12682352 0.602 rs6993494 chr8:8667444 C/T cg08975724 chr8:8085496 FLJ10661 0.52 4.46 0.37 1.84e-5 Neuroticism; TGCT cis rs2786098 0.577 rs12046808 chr1:197818024 G/A cg00114966 chr1:197893920 LHX9 0.39 4.72 0.39 6.15e-6 Asthma; TGCT cis rs9788333 0.962 rs34853044 chr13:21883784 C/T cg10411590 chr13:21900810 NA 0.38 5.06 0.41 1.48e-6 Thiazide-induced adverse metabolic effects in hypertensive patients; TGCT trans rs7618501 1.000 rs6785549 chr3:49736565 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.04 -13.29 -0.77 1.33e-25 Intelligence (multi-trait analysis); TGCT cis rs67311347 1.000 rs12108041 chr3:40487535 C/T cg17264618 chr3:40429014 ENTPD3 0.34 4.98 0.41 2.1e-6 Renal cell carcinoma; TGCT cis rs7226408 0.802 rs72887098 chr18:34511073 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs9926296 0.546 rs9935541 chr16:89905925 G/C cg04287289 chr16:89883240 FANCA 0.72 7.27 0.55 3.59e-11 Vitiligo; TGCT cis rs9811920 0.581 rs793468 chr3:99538346 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.6 6.82 0.52 3.63e-10 Axial length; TGCT cis rs10504229 0.775 rs55734109 chr8:58162322 G/A cg08280861 chr8:58055591 NA 0.38 4.75 0.39 5.45e-6 Developmental language disorder (linguistic errors); TGCT cis rs9430161 0.579 rs11121669 chr1:11039567 T/C cg02454025 chr1:11042201 C1orf127 0.97 12.71 0.75 3.27e-24 Ewing sarcoma; TGCT cis rs78487399 0.908 rs7576643 chr2:43841269 C/T cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.62 4.46 0.37 1.84e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs2932538 0.883 rs6701351 chr1:113139196 G/A cg22162597 chr1:113214053 CAPZA1 0.25 5.6 0.45 1.34e-7 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs7267979 1.000 rs6050564 chr20:25344231 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1555895 0.611 rs12774722 chr10:854675 G/A cg02193355 chr10:851439 NA 0.2 4.55 0.38 1.28e-5 Survival in rectal cancer; TGCT cis rs28551159 1 rs28551159 chr6:26376368 A/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Urinary tract infection frequency; TGCT cis rs709400 0.628 rs11622320 chr14:103912194 A/T cg26031613 chr14:104095156 KLC1 0.88 9.75 0.66 5.05e-17 Body mass index; TGCT cis rs6840360 0.642 rs6845648 chr4:152376050 C/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.882 rs13063929 chr3:10010308 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.49 -6.62 -0.51 9.56e-10 Alzheimer's disease; TGCT cis rs6918586 0.636 rs198816 chr6:26127184 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.66 -6.22 -0.49 7.01e-9 Schizophrenia; TGCT cis rs9905704 0.647 rs12944274 chr17:57041293 C/G cg05425664 chr17:57184151 TRIM37 0.6 4.81 0.4 4.33e-6 Testicular germ cell tumor; TGCT cis rs2013441 1.000 rs2703818 chr17:20119976 T/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.61 -0.38 9.96e-6 Obesity-related traits; TGCT cis rs4819052 0.851 rs1056099 chr21:46678892 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.62 0.38 9.36e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7618915 0.547 rs62253700 chr3:52625019 T/A cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.18 0.49 8.58e-9 Bipolar disorder; TGCT cis rs116095464 0.558 rs62346508 chr5:203668 T/C cg12570787 chr5:219185 SDHA;CCDC127 0.73 4.63 0.38 9.01e-6 Breast cancer; TGCT cis rs7666738 0.830 rs35938349 chr4:98974998 T/C cg05340658 chr4:99064831 C4orf37 0.5 5.72 0.46 7.3900000000000007e-08 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.681 rs540031 chr15:43608855 C/T cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.51 0.61 4.91e-14 Lung cancer in ever smokers; TGCT cis rs2639990 1.000 rs655156 chr18:72898181 T/C cg21330207 chr18:72916311 ZADH2 0.52 4.61 0.38 9.8e-6 Vascular endothelial growth factor levels; TGCT cis rs1997103 1.000 rs4628219 chr7:55410449 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs67072384 0.818 rs2291291 chr11:72466897 T/C cg03713592 chr11:72463424 ARAP1 -0.93 -4.68 -0.39 7.3e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs3780378 0.935 rs2149560 chr9:5082106 G/T cg02405213 chr9:5042618 JAK2 -0.62 -8.3 -0.6 1.48e-13 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs1799949 0.894 rs71367985 chr17:41374463 G/A cg10047753 chr17:41438598 NA 0.81 7.67 0.57 4.38e-12 Menopause (age at onset); TGCT trans rs1814175 0.817 rs1794162 chr11:49899506 A/C cg15704280 chr7:45808275 SEPT13 -0.71 -8.02 -0.58 6.85e-13 Height; TGCT cis rs9902453 0.933 rs1128156 chr17:28513176 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 0.72 6.39 0.5 3.03e-9 Coffee consumption (cups per day); TGCT cis rs912057 0.601 rs1294411 chr6:6739034 T/C cg06612196 chr6:6737390 NA 0.49 7.31 0.55 2.85e-11 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs875971 0.638 rs35986979 chr7:66088990 G/A cg18876405 chr7:65276391 NA -0.36 -5.41 -0.44 3.12e-7 Aortic root size; TGCT cis rs1215050 0.791 rs165250 chr4:98696259 G/A cg05340658 chr4:99064831 C4orf37 0.44 5.52 0.44 1.85e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs8032315 0.965 rs7497304 chr15:91429176 G/T cg04510874 chr15:91427884 FES 0.51 5.71 0.46 7.76e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs936229 0.651 rs12908814 chr15:75132490 C/G cg10253484 chr15:75165896 SCAMP2 -0.52 -4.79 -0.4 4.59e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs2014572 0.904 rs10412465 chr19:57753931 T/C cg24459738 chr19:57751996 ZNF805 -0.57 -5.53 -0.44 1.84e-7 Hyperactive-impulsive symptoms; TGCT cis rs6969780 0.632 rs11762730 chr7:27190398 A/C cg04317399 chr7:27170313 HOXA4 -0.37 -4.77 -0.39 5.05e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs6840360 0.615 rs72728171 chr4:152469372 C/A cg17479576 chr4:152424074 FAM160A1 -0.71 -7.74 -0.57 2.96e-12 Intelligence (multi-trait analysis); TGCT cis rs644799 1.000 rs481630 chr11:95582447 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.91 10.43 0.68 1.13e-18 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9611565 0.729 rs73176689 chr22:41782633 T/C cg06481639 chr22:41940642 POLR3H -0.75 -6.67 -0.51 7.59e-10 Vitiligo; TGCT cis rs58688157 0.880 rs12272314 chr11:590648 A/G cg16486109 chr11:613632 IRF7 0.35 5.19 0.42 8.4e-7 Systemic lupus erythematosus; TGCT cis rs346785 0.692 rs6501881 chr17:74289839 G/A cg09812376 chr17:74270190 QRICH2 -0.36 -5.33 -0.43 4.43e-7 White matter hyperintensities in ischemic stroke; TGCT cis rs1552244 1.000 rs6442147 chr3:10078247 A/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs6835098 0.961 rs28709762 chr4:174099149 T/C cg08422745 chr4:174089978 GALNT7 -0.9 -10.08 -0.67 7.91e-18 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs28386778 0.897 rs4968663 chr17:61835603 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs6088590 0.931 rs6088624 chr20:33436852 T/A cg06115741 chr20:33292138 TP53INP2 0.62 5.07 0.41 1.43e-6 Coronary artery disease; TGCT cis rs881375 0.967 rs10739579 chr9:123694788 C/A cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.99 0.41 2.03e-6 Rheumatoid arthritis; TGCT cis rs73198271 0.613 rs11249892 chr8:8657240 C/T cg06671706 chr8:8559999 CLDN23 -0.36 -4.52 -0.38 1.42e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs9399135 0.967 rs4895439 chr6:135318854 A/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.36e-6 Red blood cell count; TGCT cis rs807669 0.903 rs1771540 chr22:19173933 T/A cg02655711 chr22:19163373 SLC25A1 0.42 9.92 0.67 1.94e-17 Metabolite levels; TGCT cis rs748404 0.631 rs6493083 chr15:43637985 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.45 4.64 0.38 8.62e-6 Lung cancer; TGCT cis rs6534347 0.597 rs7698404 chr4:123507053 G/C cg10583651 chr4:123538969 IL21 -0.32 -4.49 -0.37 1.63e-5 Type 1 diabetes; TGCT cis rs1005277 0.579 rs2472182 chr10:38388865 T/C cg13531842 chr10:38383804 ZNF37A -0.38 -4.51 -0.38 1.49e-5 Extrinsic epigenetic age acceleration; TGCT cis rs11190604 1.000 rs11190587 chr10:102266638 C/T cg23241863 chr10:102295624 HIF1AN 0.66 4.86 0.4 3.55e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9814567 1.000 rs4974493 chr3:134219993 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs13217239 0.646 rs10456352 chr6:26990358 A/T cg05738196 chr6:26577821 NA 0.49 4.78 0.39 4.97e-6 Schizophrenia; TGCT cis rs56036086 0.824 rs56308603 chr22:50630794 G/A cg01548456 chr22:50352384 NA 0.37 5.26 0.43 5.98e-7 Platelet count;Plateletcrit; TGCT cis rs864745 0.967 rs1708302 chr7:28198677 C/T cg23620719 chr7:28220237 JAZF1 -0.49 -4.58 -0.38 1.11e-5 Crohn's disease;Type 2 diabetes; TGCT cis rs6879260 0.963 rs11738924 chr5:179727308 A/G cg02891314 chr5:179741120 GFPT2 -0.39 -6.43 -0.5 2.46e-9 Height; TGCT cis rs10493773 0.609 rs11161660 chr1:86184066 C/T cg17807903 chr1:86174739 ZNHIT6 -0.52 -8.16 -0.59 3.27e-13 Urate levels in overweight individuals; TGCT cis rs7586879 0.616 rs6545814 chr2:25131316 A/G cg01884057 chr2:25150051 NA 0.34 6.56 0.51 1.3e-9 Body mass index; TGCT cis rs6840360 0.593 rs6855883 chr4:152688997 A/G cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.63e-8 Intelligence (multi-trait analysis); TGCT cis rs1215050 0.682 rs6839343 chr4:98839732 G/A cg17366294 chr4:99064904 C4orf37 0.57 5.0 0.41 1.95e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6992820 0.967 rs7816281 chr8:56696726 G/A cg06880721 chr8:56792545 LYN -0.53 -4.5 -0.37 1.53e-5 Mean platelet volume; TGCT cis rs4853012 0.838 rs6715351 chr2:74346119 G/A cg19729930 chr2:74357872 NA 0.65 9.35 0.64 4.6e-16 Gestational age at birth (maternal effect); TGCT cis rs7949030 0.626 rs72927213 chr11:62351198 G/C cg22862634 chr11:62369728 EML3;MTA2 0.7 8.89 0.62 6.15e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9677476 1.000 rs7584535 chr2:232106857 C/T cg07929768 chr2:232055508 NA 0.3 4.48 0.37 1.71e-5 Food antigen IgG levels; TGCT cis rs8077889 0.703 rs72836567 chr17:41945776 G/A cg26893861 chr17:41843967 DUSP3 1.05 9.84 0.66 3.08e-17 Triglycerides; TGCT cis rs7666738 0.830 rs11097582 chr4:98772201 G/A cg17366294 chr4:99064904 C4orf37 0.65 6.79 0.52 4.13e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9796 0.624 rs9920619 chr15:41318845 A/G cg18705301 chr15:41695430 NDUFAF1 -0.47 -5.96 -0.47 2.49e-8 Menopause (age at onset); TGCT cis rs191220855 1 rs191220855 chr2:200778130 A/G cg23649088 chr2:200775458 C2orf69 -0.45 -6.15 -0.48 9.86e-9 Chickenpox; TGCT cis rs9388451 0.839 rs4897157 chr6:126102981 A/T cg05901451 chr6:126070800 HEY2 -1.0 -14.45 -0.79 2.37e-28 Brugada syndrome; TGCT cis rs4803455 0.565 rs11083616 chr19:41865643 A/G cg09537434 chr19:41945824 ATP5SL 0.51 5.01 0.41 1.85e-6 Migraine;Coronary artery disease; TGCT cis rs7917772 0.503 rs7096072 chr10:104299976 C/T cg05855489 chr10:104503620 C10orf26 -0.58 -5.06 -0.41 1.47e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4713118 0.547 rs2116981 chr6:28067951 T/G cg12963246 chr6:28129442 ZNF389 0.51 5.02 0.41 1.73e-6 Parkinson's disease; TGCT cis rs6912958 0.559 rs107690 chr6:88069352 A/G cg12350822 chr6:88032061 C6orf162;GJB7 -0.42 -5.57 -0.45 1.51e-7 Monocyte percentage of white cells; TGCT cis rs10504229 0.906 rs113823909 chr8:58170635 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.57e-7 Developmental language disorder (linguistic errors); TGCT cis rs1580019 0.844 rs1037322 chr7:32501857 C/T cg06627557 chr7:32535165 LSM5;AVL9 0.88 8.65 0.61 2.23e-14 Cognitive ability; TGCT cis rs1568889 1.000 rs61889027 chr11:28281908 C/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.83 8.06 0.59 5.42e-13 Bipolar disorder; TGCT cis rs7584330 0.910 rs6737914 chr2:238393434 A/G cg14458575 chr2:238380390 NA 0.45 6.77 0.52 4.52e-10 Prostate cancer; TGCT cis rs826838 1.000 rs826889 chr12:39101076 G/A cg26384229 chr12:38710491 ALG10B -0.88 -8.19 -0.59 2.72e-13 Heart rate; TGCT cis rs10479542 0.892 rs7736163 chr5:178980316 G/C cg21226059 chr5:178986404 RUFY1 0.46 5.02 0.41 1.75e-6 Lung cancer; TGCT cis rs4851266 0.898 rs10496346 chr2:100853267 A/G cg22139774 chr2:100720529 AFF3 0.31 4.55 0.38 1.27e-5 Educational attainment; TGCT cis rs10276381 0.786 rs28430601 chr7:28238811 A/G cg23620719 chr7:28220237 JAZF1 1.01 5.39 0.44 3.36e-7 Crohn's disease; TGCT cis rs3820928 0.874 rs7423610 chr2:227836262 A/G cg11843606 chr2:227700838 RHBDD1 -0.52 -4.58 -0.38 1.1e-5 Pulmonary function; TGCT cis rs2153535 0.504 rs4493781 chr6:8473941 G/C cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.3e-6 Motion sickness; TGCT cis rs3820068 0.581 rs16849152 chr1:15921774 A/C cg05660106 chr1:15850417 CASP9 0.83 8.29 0.6 1.58e-13 Systolic blood pressure; TGCT cis rs10504229 1.000 rs949848 chr8:58169125 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs116095464 0.558 rs10059907 chr5:205360 G/C cg12570787 chr5:219185 SDHA;CCDC127 0.71 4.51 0.38 1.48e-5 Breast cancer; TGCT trans rs877282 0.898 rs35743076 chr10:758991 C/T cg22713356 chr15:30763199 NA 1.12 8.42 0.6 7.78e-14 Uric acid levels; TGCT cis rs7267979 1.000 rs2500446 chr20:25339664 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9611565 0.694 rs5758347 chr22:41821019 G/T cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs11118844 0.843 rs58850477 chr1:221927229 G/A cg04222084 chr1:221915650 DUSP10 -0.89 -6.09 -0.48 1.28e-8 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs1008375 0.898 rs10008445 chr4:17593978 G/T cg16339924 chr4:17578868 LAP3 0.81 6.69 0.52 6.75e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9467773 1.000 rs6940053 chr6:26562122 C/T cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT trans rs62103177 0.714 rs12607447 chr18:77605212 A/G cg05926928 chr17:57297772 GDPD1 1.05 10.15 0.67 5.52e-18 Opioid sensitivity; TGCT cis rs28386778 0.863 rs3760256 chr17:61821161 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.1 0.82 3.69e-32 Prudent dietary pattern; TGCT cis rs12135062 0.851 rs2651927 chr1:3101762 A/C cg00254258 chr1:3105189 PRDM16 -0.35 -5.74 -0.46 6.91e-8 Migraine; TGCT cis rs1218582 0.600 rs72702224 chr1:154911689 G/A cg06418219 chr1:154948305 SHC1;CKS1B -0.64 -6.5 -0.5 1.79e-9 Prostate cancer; TGCT cis rs1153858 1.000 rs16942000 chr15:45633003 C/T cg14582100 chr15:45693742 SPATA5L1 0.48 5.7 0.46 8.17e-8 Homoarginine levels; TGCT cis rs7178572 0.568 rs12916731 chr15:77507021 C/T cg22256960 chr15:77711686 NA -0.87 -8.87 -0.62 6.78e-15 Type 2 diabetes; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg19723775 chr5:179050963 HNRNPH1 0.51 5.18 0.42 8.81e-7 Lung cancer; TGCT cis rs9616064 0.813 rs9627512 chr22:46977702 C/T cg04500879 chr22:46327243 WNT7B 0.28 4.57 0.38 1.17e-5 Urate levels in obese individuals; TGCT cis rs9926296 0.681 rs12923946 chr16:89821080 C/T cg08627397 chr16:89984028 MC1R -0.29 -4.59 -0.38 1.07e-5 Vitiligo; TGCT cis rs79349575 0.715 rs55724082 chr17:47017879 G/A cg26022315 chr17:47021804 SNF8 0.5 4.96 0.41 2.23e-6 Type 2 diabetes; TGCT cis rs769267 0.931 rs15622 chr19:19468734 G/A cg19010396 chr19:19431384 KIAA0892;SF4 -0.56 -4.58 -0.38 1.13e-5 Tonsillectomy; TGCT trans rs1005277 0.579 rs2504143 chr10:38383706 C/T cg27523141 chr10:43048294 ZNF37B 0.74 8.66 0.61 2.13e-14 Extrinsic epigenetic age acceleration; TGCT cis rs10904887 0.846 rs1885396 chr10:17243351 C/T cg01003015 chr10:17271136 VIM -0.6 -5.46 -0.44 2.5e-7 Telomere length; TGCT cis rs769267 1.000 rs12985655 chr19:19442434 G/A cg03709012 chr19:19516395 GATAD2A -0.66 -5.7 -0.46 8.46e-8 Tonsillectomy; TGCT cis rs9486719 1.000 rs3798295 chr6:97052164 C/T cg18709589 chr6:96969512 KIAA0776 -0.74 -5.21 -0.42 7.5e-7 Migraine;Coronary artery disease; TGCT cis rs9916302 0.706 rs667239 chr17:37442241 A/G cg07936489 chr17:37558343 FBXL20 0.81 5.99 0.47 2.16e-8 Glomerular filtration rate (creatinine); TGCT cis rs4478858 0.735 rs7556340 chr1:31788453 A/T cg07478791 chr1:31886160 SERINC2 -0.51 -4.93 -0.41 2.55e-6 Alcohol dependence; TGCT cis rs2239547 0.603 rs17304995 chr3:53070755 A/G cg11645453 chr3:52864694 ITIH4 0.32 5.02 0.41 1.72e-6 Schizophrenia; TGCT cis rs35000415 0.938 rs13239597 chr7:128695983 C/A cg06242719 chr7:129414860 MIR183;MIR96 -0.34 -4.67 -0.39 7.73e-6 Systemic lupus erythematosus; TGCT cis rs1129187 0.755 rs3818554 chr6:42934620 C/T cg17345569 chr6:42928274 GNMT -0.48 -4.91 -0.4 2.82e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs873946 0.648 rs12766050 chr10:134549108 G/A cg18305652 chr10:134549665 INPP5A 0.35 5.64 0.45 1.1e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs6993813 0.620 rs4546691 chr8:120025004 G/A cg17171407 chr8:119960777 TNFRSF11B 0.26 4.66 0.39 8.02e-6 Bone mineral density (hip); TGCT cis rs9467773 0.572 rs3846846 chr6:26445039 A/G cg05738196 chr6:26577821 NA -0.52 -5.49 -0.44 2.18e-7 Intelligence (multi-trait analysis); TGCT cis rs9913156 0.793 rs7210953 chr17:4608870 C/T cg19197139 chr17:4613644 ARRB2 0.83 7.74 0.57 3.03e-12 Lymphocyte counts; TGCT cis rs8033133 0.602 rs12438531 chr15:25323876 A/C cg14481604 chr15:25334117 SNORD116-22 -0.23 -5.17 -0.42 9.25e-7 Blood osmolality (transformed sodium); TGCT cis rs7264396 0.733 rs6060515 chr20:34211779 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.67 -0.39 7.62e-6 Total cholesterol levels; TGCT cis rs7312933 0.558 rs11181507 chr12:42844763 T/A cg19980929 chr12:42632907 YAF2 0.43 6.13 0.48 1.08e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9733 0.544 rs72700902 chr1:150633347 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs28386778 0.830 rs6504180 chr17:61813169 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs7829975 0.748 rs693109 chr8:8640172 C/A cg15556689 chr8:8085844 FLJ10661 -0.69 -6.05 -0.48 1.62e-8 Mood instability; TGCT cis rs7781977 0.644 rs10269380 chr7:50354512 G/A cg14216940 chr7:50343131 IKZF1 0.36 4.51 0.38 1.48e-5 IgG glycosylation; TGCT trans rs10435719 0.867 rs35778860 chr8:11791338 C/T cg15556689 chr8:8085844 FLJ10661 0.75 7.26 0.55 3.66e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg04608855 chr19:58913158 NA 0.58 5.64 0.45 1.11e-7 Uric acid clearance; TGCT cis rs6665290 0.904 rs1045286 chr1:227179037 A/C cg10327440 chr1:227177885 CDC42BPA 0.91 17.25 0.84 9.67e-35 Myeloid white cell count; TGCT cis rs7772486 0.790 rs80050589 chr6:146230454 T/C cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs28818218 chr4:98880575 A/C cg05340658 chr4:99064831 C4orf37 0.54 6.13 0.48 1.06e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7542091 0.579 rs34638782 chr1:210032055 C/G cg22029157 chr1:209979665 IRF6 0.51 4.92 0.4 2.68e-6 Monobrow; TGCT cis rs1878931 0.582 rs4785933 chr16:3419741 T/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 6.35 0.5 3.66e-9 Body mass index (adult); TGCT cis rs9467773 1.000 rs10214634 chr6:26564582 T/A cg26531700 chr6:26746687 NA 0.49 4.73 0.39 6.06e-6 Intelligence (multi-trait analysis); TGCT cis rs709400 0.930 rs28513222 chr14:104028069 A/T cg26031613 chr14:104095156 KLC1 1.16 15.24 0.81 3.33e-30 Body mass index; TGCT cis rs2688608 0.905 rs2633300 chr10:75656647 A/C cg04320760 chr10:75533139 FUT11 -0.3 -4.58 -0.38 1.1e-5 Inflammatory bowel disease; TGCT cis rs11711311 0.866 rs13313893 chr3:113400856 A/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.77 -7.04 -0.53 1.16e-10 IgG glycosylation; TGCT cis rs644799 0.710 rs10831429 chr11:95508524 C/A cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.29 0.6 1.54e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs28386778 0.897 rs3785572 chr17:61829989 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.12 0.42 1.15e-6 Prudent dietary pattern; TGCT cis rs28595532 0.764 rs115986119 chr4:119767785 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs694739 1.000 rs694739 chr11:64097233 A/G cg02228329 chr11:64053129 BAD;GPR137 0.79 7.87 0.58 1.54e-12 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs4711350 0.862 rs530614 chr6:33714781 G/A cg18005901 chr6:33739558 LEMD2 0.57 5.94 0.47 2.62e-8 Schizophrenia; TGCT trans rs7613875 0.600 rs2856237 chr3:50158774 A/G cg21659725 chr3:3221576 CRBN -0.69 -7.57 -0.56 7.35e-12 Body mass index; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg18538332 chr22:24372958 LOC391322 -1.01 -12.89 -0.76 1.18e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1008375 0.966 rs7666888 chr4:17695722 C/T cg18681998 chr4:17616180 MED28 0.75 7.38 0.55 2e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7191439 0.583 rs9935872 chr16:88788477 A/G cg27087555 chr16:88793112 FAM38A -0.43 -4.81 -0.4 4.34e-6 Plateletcrit; TGCT cis rs6912958 0.559 rs242267 chr6:88061837 A/G cg08069147 chr6:88032118 GJB7;C6orf162 -0.69 -7.11 -0.54 8.14e-11 Monocyte percentage of white cells; TGCT cis rs6987853 0.901 rs2923429 chr8:42389743 A/G cg20539142 chr8:42623718 CHRNA6 -0.21 -5.03 -0.41 1.69e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs3806843 0.900 rs2337983 chr5:140136808 G/A cg19875535 chr5:140030758 IK -0.36 -6.16 -0.48 9.15e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs5769765 0.908 rs4074304 chr22:50309446 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.24 -12.96 -0.76 8.23e-25 Schizophrenia; TGCT trans rs561341 0.505 rs548298 chr17:30297494 C/A cg20587970 chr11:113659929 NA -1.03 -10.98 -0.7 5.21e-20 Hip circumference adjusted for BMI; TGCT cis rs7666738 0.830 rs13106434 chr4:98991651 T/A cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg23131131 chr22:24373011 LOC391322 -0.8 -8.64 -0.61 2.41e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs35146811 0.625 rs2906645 chr7:99817859 A/G cg04778012 chr7:99775508 STAG3;GPC2 -0.36 -5.1 -0.42 1.22e-6 Coronary artery disease; TGCT cis rs7954584 0.616 rs10743186 chr12:122356436 C/T cg13699009 chr12:122356056 WDR66 0.32 7.33 0.55 2.6e-11 Mean corpuscular volume; TGCT cis rs13242816 1.000 rs12669740 chr7:116138576 T/C cg02799643 chr7:116139180 CAV2 -0.45 -5.85 -0.47 4.03e-8 P wave duration; TGCT cis rs2032447 0.670 rs198850 chr6:26104670 A/C cg12310025 chr6:25882481 NA 0.53 4.83 0.4 4.01e-6 Intelligence (multi-trait analysis); TGCT cis rs849210 0.517 rs3856509 chr2:206180836 A/G cg11793701 chr2:206547163 NRP2 -0.54 -4.49 -0.37 1.62e-5 Tonsillectomy; TGCT cis rs1372520 0.935 rs1372519 chr4:90757309 A/G cg01966878 chr4:90757139 SNCA -0.3 -4.59 -0.38 1.09e-5 Neuroticism; TGCT cis rs2204008 0.713 rs11173567 chr12:38089375 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.65 0.57 4.91e-12 Bladder cancer; TGCT cis rs7267979 0.903 rs2500400 chr20:25354705 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs34638657 0.732 rs4889477 chr16:82201302 C/T cg09439754 chr16:82129088 HSD17B2 -0.24 -4.53 -0.38 1.37e-5 Lung adenocarcinoma; TGCT cis rs2228479 0.850 rs76075456 chr16:89834270 T/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs3785574 0.927 rs2854160 chr17:61977248 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.99 11.35 0.71 6.6e-21 Height; TGCT cis rs3026101 0.576 rs56188406 chr17:5316769 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.78 0.39 4.97e-6 Body mass index; TGCT cis rs17767294 0.708 rs72846792 chr6:28133311 C/T cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs10504229 0.906 rs114627636 chr8:58173732 C/T cg24829409 chr8:58192753 C8orf71 -0.64 -5.31 -0.43 4.89e-7 Developmental language disorder (linguistic errors); TGCT cis rs1799949 1.000 rs36036395 chr17:41181297 T/C cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs2172802 0.570 rs2343526 chr4:62521386 T/C cg04118610 chr4:62707027 LPHN3 0.42 4.95 0.41 2.41e-6 Partial epilepsies; TGCT cis rs951366 0.528 rs1172198 chr1:205662718 C/T cg14893161 chr1:205819251 PM20D1 0.51 6.98 0.53 1.54e-10 Menarche (age at onset); TGCT cis rs10174077 0.874 rs10186656 chr2:152475938 T/G cg06191203 chr2:152266755 RIF1 -0.69 -6.39 -0.5 3.05e-9 Squamous cell lung carcinoma; TGCT cis rs7824557 0.628 rs6988922 chr8:11194911 A/G cg21775007 chr8:11205619 TDH 0.7 6.86 0.52 2.93e-10 Retinal vascular caliber; TGCT cis rs739496 0.579 rs12316525 chr12:112344119 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs4851254 0.618 rs35840153 chr2:100669829 A/G cg07810366 chr2:100720526 AFF3 -0.49 -5.04 -0.41 1.61e-6 Intelligence (multi-trait analysis); TGCT cis rs9457247 1.000 rs10946198 chr6:167404432 C/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs1843834 0.721 rs1434057 chr2:225606389 T/G cg22455342 chr2:225449267 CUL3 0.65 6.26 0.49 5.64e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs4906332 0.782 rs12891288 chr14:103999750 C/T cg26031613 chr14:104095156 KLC1 -0.58 -4.68 -0.39 7.51e-6 Coronary artery disease; TGCT cis rs826838 0.900 rs11169301 chr12:39128497 C/A cg13010199 chr12:38710504 ALG10B 0.72 5.75 0.46 6.7e-8 Heart rate; TGCT cis rs9393692 0.905 rs9379838 chr6:26277133 C/T cg00631329 chr6:26305371 NA -0.41 -6.09 -0.48 1.34e-8 Educational attainment; TGCT cis rs739496 0.615 rs7312260 chr12:112358663 T/G cg10833066 chr12:111807467 FAM109A 0.38 5.42 0.44 2.97e-7 Platelet count; TGCT cis rs7647973 0.925 rs9834003 chr3:49216472 T/C cg05785598 chr3:49045655 WDR6 0.38 4.68 0.39 7.48e-6 Menarche (age at onset); TGCT cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg14983838 chr19:29218262 NA 0.83 6.76 0.52 4.75e-10 Methadone dose in opioid dependence; TGCT cis rs7586879 0.593 rs10198275 chr2:25130542 A/C cg01884057 chr2:25150051 NA 0.36 7.09 0.54 8.92e-11 Body mass index; TGCT cis rs751728 0.664 rs4711347 chr6:33735292 G/A cg13859433 chr6:33739653 LEMD2 -0.32 -5.83 -0.46 4.46e-8 Crohn's disease; TGCT cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs4523957 0.583 rs1565763 chr17:2055300 T/C cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.69e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs11874712 0.527 rs1866321 chr18:43698309 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.49 4.86 0.4 3.47e-6 Migraine - clinic-based; TGCT cis rs7681440 0.874 rs1372523 chr4:90775923 G/A cg26578617 chr4:90757533 SNCA -0.44 -4.54 -0.38 1.31e-5 Dementia with Lewy bodies; TGCT cis rs9650657 0.675 rs2409658 chr8:10668965 A/G cg27411982 chr8:10470053 RP1L1 -0.22 -5.0 -0.41 1.9e-6 Neuroticism; TGCT cis rs514406 0.679 rs11206006 chr1:53218380 A/G cg01802117 chr1:53393560 SCP2 0.5 6.0 0.47 2.05e-8 Monocyte count; TGCT cis rs4808199 0.947 rs751858 chr19:19602821 G/C cg20644253 chr19:19431407 KIAA0892;SF4 0.75 5.42 0.44 2.93e-7 Nonalcoholic fatty liver disease; TGCT cis rs2688608 0.967 rs2633299 chr10:75656754 T/G cg04320760 chr10:75533139 FUT11 -0.3 -4.58 -0.38 1.1e-5 Inflammatory bowel disease; TGCT cis rs9733 0.519 rs12095002 chr1:150649249 G/A cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs477895 0.653 rs11601577 chr11:63928574 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.76 6.03 0.48 1.71e-8 Mean platelet volume; TGCT cis rs739496 0.649 rs666727 chr12:111989658 C/T cg10833066 chr12:111807467 FAM109A 0.37 5.17 0.42 8.98e-7 Platelet count; TGCT cis rs6693567 0.565 rs1260374 chr1:150331593 G/A cg09579323 chr1:150459698 TARS2 0.54 4.79 0.4 4.59e-6 Migraine; TGCT cis rs1865760 0.963 rs9356991 chr6:25901758 C/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.24 0.49 6.27e-9 Height; TGCT cis rs8103278 0.894 rs74821481 chr19:46320041 G/T cg11657440 chr19:46296263 DMWD -0.6 -5.72 -0.46 7.58e-8 Coronary artery disease; TGCT cis rs35883536 0.513 rs6577180 chr1:101016939 G/A cg10298815 chr1:101004474 GPR88 0.25 4.71 0.39 6.56e-6 Monocyte count; TGCT cis rs5769765 0.773 rs138834 chr22:50180497 A/C cg26441486 chr22:50317300 CRELD2 0.31 4.67 0.39 7.63e-6 Schizophrenia; TGCT cis rs6088590 1.000 rs6120708 chr20:33335526 G/A cg06115741 chr20:33292138 TP53INP2 0.67 5.61 0.45 1.24e-7 Coronary artery disease; TGCT cis rs736408 0.812 rs1075653 chr3:52825528 T/C cg07507251 chr3:52567010 NT5DC2 0.45 6.12 0.48 1.13e-8 Bipolar disorder; TGCT cis rs9486719 0.895 rs4486019 chr6:96883814 T/C cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT trans rs208520 0.690 rs1776365 chr6:66834474 G/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.96 -10.43 -0.68 1.13e-18 Exhaled nitric oxide output; TGCT cis rs78487399 0.710 rs72881068 chr2:43690860 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.56 -0.45 1.57e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs3907021 chr4:99038668 C/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs17376456 0.696 rs6860390 chr5:93494731 G/T cg25358565 chr5:93447407 FAM172A -0.63 -5.94 -0.47 2.74e-8 Diabetic retinopathy; TGCT cis rs6088590 1.000 rs2295353 chr20:33356511 C/T cg06115741 chr20:33292138 TP53INP2 0.67 5.6 0.45 1.34e-7 Coronary artery disease; TGCT cis rs8180040 0.764 rs4082155 chr3:47125385 G/A cg27129171 chr3:47204927 SETD2 0.74 9.79 0.66 4.15e-17 Colorectal cancer; TGCT cis rs7666738 0.830 rs1426669 chr4:98945534 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2760061 0.598 rs632832 chr1:228121838 G/T cg18477163 chr1:228402036 OBSCN -0.32 -6.37 -0.5 3.31e-9 Diastolic blood pressure; TGCT cis rs78487399 0.808 rs13414619 chr2:43699406 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.42 -5.56 -0.45 1.57e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs571497 0.697 rs62128260 chr19:7833876 T/A cg07381814 chr19:8576031 ZNF414 -0.3 -4.57 -0.38 1.18e-5 Monocyte count; TGCT trans rs1496653 0.602 rs35021696 chr3:23479478 A/C cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs9660180 0.934 rs34849348 chr1:1762757 C/T cg23982607 chr1:1823379 GNB1 -0.55 -8.5 -0.61 5.16e-14 Body mass index; TGCT cis rs6951245 1.000 rs113858334 chr7:1073476 A/G cg23708337 chr7:1209742 NA 0.51 4.46 0.37 1.78e-5 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7804356 0.651 rs73061889 chr7:26799874 A/C cg03456212 chr7:26904342 SKAP2 -0.54 -4.6 -0.38 1.04e-5 Type 1 diabetes; TGCT cis rs739496 0.542 rs7399251 chr12:111802680 C/T cg10833066 chr12:111807467 FAM109A 0.47 7.09 0.54 9.07e-11 Platelet count; TGCT cis rs35160687 0.901 rs12714179 chr2:86514958 T/C cg12542933 chr2:85804724 VAMP8 0.4 4.79 0.39 4.75e-6 Night sleep phenotypes; TGCT cis rs3091242 0.933 rs12402120 chr1:25751632 C/T cg09222892 chr1:25734099 RHCE -0.43 -6.92 -0.53 2.09e-10 Erythrocyte sedimentation rate; TGCT cis rs2933343 0.903 rs2638846 chr3:128587163 A/T cg11901034 chr3:128598214 ACAD9 -0.62 -5.16 -0.42 9.47e-7 IgG glycosylation; TGCT cis rs28595532 0.841 rs114363775 chr4:119765587 G/A cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs4665809 0.838 rs6546780 chr2:26352857 T/C cg25036284 chr2:26402008 FAM59B -0.53 -4.58 -0.38 1.1e-5 Gut microbiome composition (summer); TGCT cis rs7843479 0.601 rs2306645 chr8:21845428 C/T cg17168535 chr8:21777572 XPO7 -0.8 -7.93 -0.58 1.11e-12 Mean corpuscular volume; TGCT cis rs2290405 0.527 rs7663192 chr4:923947 T/C cg04824913 chr4:887549 GAK 0.35 4.75 0.39 5.64e-6 Systemic sclerosis; TGCT cis rs7769051 0.711 rs7770081 chr6:133089569 G/T cg07930552 chr6:133119739 C6orf192 0.93 5.0 0.41 1.87e-6 Type 2 diabetes nephropathy; TGCT cis rs1218582 0.772 rs4845690 chr1:154886817 C/T cg06221963 chr1:154839813 KCNN3 0.76 12.91 0.76 1.09e-24 Prostate cancer; TGCT cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.61 -6.27 -0.49 5.54e-9 Intelligence (multi-trait analysis); TGCT cis rs1843834 0.539 rs10177898 chr2:225437552 C/T cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs10992471 0.603 rs12341817 chr9:95252152 C/T cg14631576 chr9:95140430 CENPP -0.31 -4.61 -0.38 9.95e-6 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12188164 0.965 rs11739543 chr5:443676 G/A cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.71 -0.39 6.42e-6 Cystic fibrosis severity; TGCT cis rs2239547 0.603 rs2276825 chr3:52886605 T/C cg11645453 chr3:52864694 ITIH4 0.35 5.77 0.46 5.97e-8 Schizophrenia; TGCT cis rs2032447 0.798 rs807214 chr6:26061769 G/C cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.59 -5.71 -0.46 7.79e-8 Intelligence (multi-trait analysis); TGCT cis rs4824093 0.610 rs73441787 chr22:50269646 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.11 -6.79 -0.52 4.13e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs2120019 1.000 rs12185102 chr15:75352201 G/A cg17294928 chr15:75287854 SCAMP5 -0.81 -6.21 -0.49 7.41e-9 Blood trace element (Zn levels); TGCT cis rs6089829 0.962 rs6011548 chr20:61666063 C/T cg08045932 chr20:61659980 NA 0.49 9.25 0.64 8.4e-16 Prostate cancer (SNP x SNP interaction); TGCT trans rs7613875 0.580 rs6808044 chr3:50136165 A/G cg21659725 chr3:3221576 CRBN -0.69 -7.51 -0.56 9.95e-12 Body mass index; TGCT cis rs1008375 0.902 rs12503164 chr4:17656107 C/T cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 1.000 rs6083862 chr20:25411086 A/T cg14121845 chr20:25566513 NINL -0.46 -4.99 -0.41 2.01e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs868036 0.609 rs3784707 chr15:68043878 A/C cg27219399 chr15:67835830 MAP2K5 0.34 4.44 0.37 1.94e-5 Restless legs syndrome; TGCT cis rs597539 0.652 rs10792001 chr11:68637737 G/C cg04772025 chr11:68637568 NA 0.59 6.69 0.52 6.73e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs12908161 1.000 rs4643294 chr15:85250253 C/T cg17173187 chr15:85201210 NMB 0.59 6.77 0.52 4.55e-10 Schizophrenia; TGCT cis rs6582630 0.519 rs12578283 chr12:38325349 A/T cg26384229 chr12:38710491 ALG10B 0.83 7.27 0.55 3.51e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs7308116 1.000 rs7311985 chr12:108236335 C/T cg19508191 chr12:109124361 CORO1C -0.45 -4.46 -0.37 1.84e-5 Pelvic organ prolapse (moderate/severe); TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg22166914 chr1:53195759 ZYG11B 0.39 6.35 0.5 3.71e-9 Monocyte count; TGCT cis rs1775715 0.675 rs2808085 chr10:32148599 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.12 0.42 1.14e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs5769707 0.837 rs5769709 chr22:50021757 C/T cg05373962 chr22:49881684 NA -0.28 -5.32 -0.43 4.6e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1514658 0.903 rs13119545 chr4:119273712 C/G cg21605333 chr4:119757512 SEC24D -0.5 -4.5 -0.37 1.56e-5 Congenital heart disease (maternal effect); TGCT cis rs476633 0.708 rs28656781 chr15:41447440 C/G cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.77 -0.62 1.18e-14 Glomerular filtration rate (creatinine); TGCT cis rs72945132 0.882 rs72945194 chr11:70138621 A/G cg00319359 chr11:70116639 PPFIA1 0.97 7.07 0.54 1.01e-10 Coronary artery disease; TGCT cis rs56235845 0.694 rs11738681 chr5:176761535 A/G cg06060754 chr5:176797920 RGS14 0.4 6.28 0.49 5.16e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs4648739 0.613 rs13303201 chr1:1903712 G/T cg03688085 chr1:1910585 KIAA1751 -0.51 -8.58 -0.61 3.25e-14 Severe influenza A (H1N1) infection; TGCT cis rs6540559 0.673 rs17015224 chr1:209968918 G/A cg04352962 chr1:209979756 IRF6 0.65 4.6 0.38 1.05e-5 Cleft lip with or without cleft palate; TGCT cis rs57221529 0.608 rs11749927 chr5:668842 C/T cg09021430 chr5:549028 NA -0.32 -4.56 -0.38 1.21e-5 Lung disease severity in cystic fibrosis; TGCT cis rs739496 0.579 rs3752630 chr12:112375990 A/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9911578 1.000 rs2270097 chr17:56572070 G/A cg05425664 chr17:57184151 TRIM37 0.6 5.83 0.46 4.54e-8 Intelligence (multi-trait analysis); TGCT cis rs2439831 0.867 rs2899082 chr15:43656043 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.61 0.51 1e-9 Lung cancer in ever smokers; TGCT cis rs7937682 0.889 rs493865 chr11:111495178 A/C cg09085632 chr11:111637200 PPP2R1B -1.04 -11.19 -0.71 1.57e-20 Primary sclerosing cholangitis; TGCT cis rs68170813 0.523 rs11766131 chr7:107071138 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs9942416 0.660 rs34905687 chr5:74997736 A/G cg19683494 chr5:74908142 NA 0.58 6.41 0.5 2.77e-9 Age-related disease endophenotypes; TGCT cis rs861020 0.630 rs656566 chr1:210006603 C/T cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs453301 0.597 rs7001187 chr8:8792782 G/A cg15556689 chr8:8085844 FLJ10661 -0.63 -5.36 -0.43 3.99e-7 Joint mobility (Beighton score); TGCT cis rs7267979 0.966 rs2387885 chr20:25415224 G/A cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6570726 0.967 rs373527 chr6:145801861 C/T cg23711669 chr6:146136114 FBXO30 0.66 6.08 0.48 1.37e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs1552244 0.507 rs6443274 chr3:9995288 A/T cg00149659 chr3:10157352 C3orf10 0.65 4.78 0.39 4.85e-6 Alzheimer's disease; TGCT cis rs10089 0.953 rs13358455 chr5:127365786 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.74 6.93 0.53 2e-10 Ileal carcinoids; TGCT cis rs11190604 0.767 rs7078070 chr10:102166415 A/C cg16005271 chr10:102321736 NA 0.45 4.74 0.39 5.87e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7267979 1.000 rs6138572 chr20:25435934 G/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11030122 0.702 rs10835402 chr11:3990914 T/C cg18678763 chr11:4115507 RRM1 -0.49 -6.13 -0.48 1.08e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs250677 0.687 rs250664 chr5:148453823 C/T cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs2153535 0.560 rs2210798 chr6:8481522 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs7547997 0.685 rs1575172 chr1:158345279 A/G cg03528325 chr1:158223921 CD1A 0.33 4.56 0.38 1.22e-5 QRS duration; TGCT trans rs7824557 0.510 rs1435274 chr8:11235910 G/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.69 -0.51 7.01e-10 Retinal vascular caliber; TGCT trans rs208520 0.874 rs208456 chr6:66907942 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.93 -9.78 -0.66 4.3e-17 Exhaled nitric oxide output; TGCT cis rs473651 0.935 rs483166 chr2:239346641 C/T cg18131467 chr2:239335373 ASB1 -1.02 -15.09 -0.8 7.51e-30 Multiple system atrophy; TGCT cis rs4555082 1.000 rs66777564 chr14:105760245 A/G cg10792982 chr14:105748885 BRF1 0.23 4.6 0.38 1.01e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs9517320 0.515 rs1107379 chr13:99198921 C/T cg07423050 chr13:99094983 FARP1 -0.27 -5.42 -0.44 2.92e-7 Longevity; TGCT cis rs11785693 0.862 rs62489554 chr8:4960685 T/C cg26367366 chr8:4980734 NA 0.61 4.59 0.38 1.09e-5 Neuroticism (multi-trait analysis);Neuroticism; TGCT cis rs478304 0.654 rs1074155 chr11:65458197 C/T cg10518572 chr11:65560635 OVOL1 0.23 4.56 0.38 1.19e-5 Acne (severe); TGCT cis rs7781977 0.554 rs7797255 chr7:50351604 C/T cg01139861 chr7:50343298 IKZF1 -0.48 -5.69 -0.46 8.57e-8 IgG glycosylation; TGCT cis rs951366 0.617 rs823075 chr1:205774897 C/T cg23034840 chr1:205782522 SLC41A1 0.5 4.53 0.38 1.39e-5 Menarche (age at onset); TGCT cis rs2535633 0.602 rs2581816 chr3:53014657 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.49 4.45 0.37 1.89e-5 Body mass index; TGCT cis rs711830 1.000 rs1562315 chr2:177045482 T/A cg13092806 chr2:177043255 NA 0.81 6.37 0.5 3.34e-9 Serous invasive ovarian cancer;Epithelial ovarian cancer;Invasive epithelial ovarian cancer;Mucinous ovarian carcinoma;Low-grade serous and serous borderline ovarian cancer;Serous borderline ovarian cancer;High-grade serous ovarian cancer; TGCT cis rs1862618 0.802 rs832560 chr5:56124423 T/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs35306767 0.761 rs11253559 chr10:1044809 T/C cg26597838 chr10:835615 NA 0.6 6.63 0.51 9.45e-10 Eosinophil percentage of granulocytes; TGCT cis rs7027203 1.000 rs7856374 chr9:96529791 G/A cg13679303 chr9:96623674 NA 0.64 9.54 0.65 1.66e-16 DNA methylation (variation); TGCT cis rs7772486 0.790 rs6917482 chr6:146243581 C/T cg05347473 chr6:146136440 FBXO30 -0.51 -4.95 -0.41 2.32e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7267979 1.000 rs7268053 chr20:25328286 A/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs644799 1.000 rs580255 chr11:95577929 T/C cg03916912 chr11:95522834 CEP57;FAM76B 0.9 9.73 0.66 5.62e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs617219 0.710 rs2607141 chr5:78558635 G/T cg23987322 chr5:78407566 BHMT 0.35 4.69 0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs17102423 0.731 rs998247 chr14:65546299 C/T cg11161011 chr14:65562177 MAX -0.43 -5.91 -0.47 3.04e-8 Obesity-related traits; TGCT cis rs56104184 0.775 rs56349331 chr19:49403009 T/A cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs950776 0.648 rs57945453 chr15:78862845 C/T cg06917634 chr15:78832804 PSMA4 0.68 5.48 0.44 2.24e-7 Sudden cardiac arrest; TGCT cis rs7611238 0.560 rs4677832 chr3:195081244 G/A cg27323046 chr3:195102265 ACAP2 0.37 5.01 0.41 1.86e-6 Body mass index; TGCT cis rs1949733 1.000 rs1916326 chr4:8500023 G/A cg13073564 chr4:8508604 NA 0.47 5.05 0.41 1.55e-6 Response to antineoplastic agents; TGCT cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg02725872 chr8:58115012 NA -0.39 -4.83 -0.4 3.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs2290402 0.505 rs9328759 chr4:882845 C/T cg23332689 chr4:987652 IDUA;SLC26A1 -0.32 -4.88 -0.4 3.17e-6 Type 2 diabetes; TGCT cis rs2456568 0.802 rs10765640 chr11:93636462 C/T cg16099599 chr11:93583650 C11orf90 -0.4 -4.98 -0.41 2.04e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2692947 0.537 rs11164050 chr2:96352451 T/C cg23100626 chr2:96804247 ASTL 0.42 4.82 0.4 4.17e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT trans rs629535 0.547 rs62513420 chr8:70122597 G/A cg21567404 chr3:27674614 NA -0.53 -8.12 -0.59 3.87e-13 Dupuytren's disease; TGCT trans rs7819412 1.000 rs7819412 chr8:11045161 A/G cg15556689 chr8:8085844 FLJ10661 0.8 7.98 0.58 8.22e-13 Triglycerides; TGCT cis rs3733585 0.699 rs6449159 chr4:9960498 G/A cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7208859 0.673 rs73277984 chr17:29196133 T/C cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2980439 0.783 rs2948305 chr8:8098577 G/A cg06636001 chr8:8085503 FLJ10661 0.88 8.82 0.62 9.02e-15 Neuroticism; TGCT cis rs2074585 0.806 rs2657949 chr15:90950790 G/A cg00487526 chr15:90818384 NA -0.29 -4.47 -0.37 1.71e-5 Basophil percentage of granulocytes;White blood cell count (basophil);Basophil percentage of white cells; TGCT cis rs7666738 0.830 rs9994346 chr4:99037986 A/G cg18180107 chr4:99064573 C4orf37 0.56 4.74 0.39 5.73e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs55882075 1.000 rs55882075 chr5:179210115 C/G cg14593053 chr5:179126677 CANX 0.48 5.24 0.43 6.58e-7 Monocyte percentage of white cells; TGCT cis rs2180341 0.597 rs3798859 chr6:127663116 C/T cg24812749 chr6:127587940 RNF146 0.63 5.32 0.43 4.72e-7 Breast cancer; TGCT cis rs9985766 0.917 rs4459971 chr4:150991590 T/G cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs9430161 0.579 rs79323519 chr1:11036050 T/C cg02454025 chr1:11042201 C1orf127 0.95 10.77 0.7 1.73e-19 Ewing sarcoma; TGCT trans rs2288327 0.643 rs1559908 chr2:179336347 C/T cg14011486 chr1:26737247 LIN28 -1.07 -8.55 -0.61 3.9e-14 Atrial fibrillation; TGCT cis rs9443645 0.901 rs6912683 chr6:79543492 C/A cg09184832 chr6:79620586 NA -0.49 -5.42 -0.44 2.96e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 0.961 rs448710 chr1:76116554 T/C cg10523679 chr1:76189770 ACADM -0.93 -10.18 -0.67 4.69e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs902774 0.515 rs2363635 chr12:53354622 T/C cg14581129 chr12:53358946 NA -0.56 -6.14 -0.48 1.02e-8 Prostate cancer; TGCT cis rs6912958 0.781 rs7757636 chr6:88256092 T/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs727563 0.562 rs5758458 chr22:42154132 G/A cg06634786 chr22:41940651 POLR3H 0.86 8.01 0.58 7.16e-13 Crohn's disease;Inflammatory bowel disease; TGCT cis rs12681287 0.927 rs2976177 chr8:87332332 A/T cg27223183 chr8:87520930 FAM82B -0.88 -6.82 -0.52 3.62e-10 Caudate activity during reward; TGCT cis rs2243480 1.000 rs6949812 chr7:65387101 G/A cg18252515 chr7:66147081 NA -1.13 -6.81 -0.52 3.7e-10 Diabetic kidney disease; TGCT cis rs2842992 0.830 rs752779 chr6:160133957 G/A cg11366901 chr6:160182831 ACAT2 1.01 6.74 0.52 5.42e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs559406 0.623 rs12971201 chr18:12830538 G/A cg23598886 chr18:12777645 NA 0.37 4.49 0.37 1.6e-5 Psoriasis; TGCT cis rs4478858 0.718 rs10914329 chr1:31688441 T/A cg00250761 chr1:31883323 NA 0.29 4.78 0.39 4.9e-6 Alcohol dependence; TGCT cis rs2371030 1.000 rs1019392 chr2:211593082 A/C cg18417063 chr2:211583084 NA -0.31 -4.45 -0.37 1.91e-5 Non-small cell lung cancer; TGCT cis rs13191362 1.000 rs13190742 chr6:163008758 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.58 4.72 0.39 6.33e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs629535 0.814 rs477200 chr8:70059584 A/G cg21567404 chr3:27674614 NA 0.5 8.28 0.6 1.67e-13 Dupuytren's disease; TGCT cis rs2180341 1.000 rs7453272 chr6:127633959 C/T cg24812749 chr6:127587940 RNF146 -0.94 -6.5 -0.5 1.79e-9 Breast cancer; TGCT cis rs78456975 1.000 rs4073861 chr2:1563611 G/A cg01028140 chr2:1542097 TPO -0.33 -4.54 -0.38 1.29e-5 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs78487399 0.808 rs12105786 chr2:43676433 T/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs362272 0.524 rs13150241 chr4:3367281 A/G cg18352616 chr4:3374830 RGS12 0.23 4.54 0.38 1.31e-5 Serum sulfate level; TGCT cis rs3935685 0.934 rs61331678 chr15:77995949 G/C cg25212270 chr15:78015279 NA 0.3 6.06 0.48 1.48e-8 Intelligence (multi-trait analysis); TGCT cis rs12682352 0.602 rs13260419 chr8:8675176 A/G cg06636001 chr8:8085503 FLJ10661 0.6 5.07 0.41 1.41e-6 Neuroticism; TGCT cis rs3008870 1.000 rs2985825 chr1:67412822 T/G cg03991309 chr1:68237761 GNG12 0.27 4.57 0.38 1.18e-5 Lymphocyte percentage of white cells; TGCT cis rs10504229 0.683 rs72650839 chr8:58130029 C/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT trans rs2727020 0.729 rs10839268 chr11:49380328 G/A cg03929089 chr4:120376271 NA -0.76 -8.89 -0.62 6.02e-15 Coronary artery disease; TGCT cis rs11190604 1.000 rs2295776 chr10:102295629 G/T cg23241863 chr10:102295624 HIF1AN 0.67 5.12 0.42 1.12e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4689388 0.782 rs4262051 chr4:6281775 G/A cg00701064 chr4:6280414 WFS1 0.39 4.79 0.4 4.7e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs10504229 0.683 rs67077711 chr8:58139769 G/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs4786125 0.626 rs11077095 chr16:6916451 C/T cg03623568 chr16:6915990 A2BP1 0.43 6.08 0.48 1.39e-8 Heart rate variability traits (SDNN); TGCT cis rs7172809 0.573 rs11853696 chr15:77688417 C/T cg22256960 chr15:77711686 NA -0.5 -4.74 -0.39 5.82e-6 Glucose homeostasis traits; TGCT cis rs7666738 0.830 rs7657982 chr4:99044015 G/A cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 7.99e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6089584 0.606 rs2296082 chr20:60573983 A/G cg13770153 chr20:60521292 NA -0.41 -4.95 -0.41 2.39e-6 Body mass index; TGCT cis rs789859 0.965 rs812583 chr3:194406505 C/G cg21106136 chr3:194405973 FAM43A -0.38 -5.35 -0.43 4.08e-7 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs6598541 0.505 rs4966025 chr15:99309542 G/A cg18742785 chr15:100270048 LYSMD4 -0.26 -4.51 -0.38 1.49e-5 Urate levels; TGCT cis rs12681287 0.673 rs2976178 chr8:87332552 C/G cg27223183 chr8:87520930 FAM82B -0.94 -7.06 -0.54 1.02e-10 Caudate activity during reward; TGCT cis rs11785400 0.753 rs9694286 chr8:143737157 G/T cg24634471 chr8:143751801 JRK 0.57 5.7 0.46 8.4e-8 Schizophrenia; TGCT cis rs710216 0.536 rs710222 chr1:43413653 A/G cg03128534 chr1:43423976 SLC2A1 0.68 7.15 0.54 6.65e-11 Red cell distribution width; TGCT cis rs9911578 0.874 rs302865 chr17:56756977 A/G cg05425664 chr17:57184151 TRIM37 -0.62 -6.29 -0.49 5.01e-9 Intelligence (multi-trait analysis); TGCT cis rs1799949 0.965 rs9911630 chr17:41188342 A/G cg05368731 chr17:41323189 NBR1 0.87 8.87 0.62 6.78e-15 Menopause (age at onset); TGCT cis rs7568458 0.811 rs10175792 chr2:85761654 A/G cg02493740 chr2:85810744 VAMP5 -0.27 -5.01 -0.41 1.8e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT trans rs7618501 0.932 rs4855850 chr3:49761571 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -1.03 -13.16 -0.76 2.65e-25 Intelligence (multi-trait analysis); TGCT cis rs2677744 1.000 rs1266483 chr15:91462406 A/G cg23684204 chr15:91497937 RCCD1 0.35 5.23 0.43 7.01e-7 Attention deficit hyperactivity disorder; TGCT cis rs2836974 0.644 rs2836982 chr21:40689171 C/A cg11644478 chr21:40555479 PSMG1 -0.55 -4.77 -0.39 5.12e-6 Cognitive function; TGCT cis rs763121 0.853 rs2076028 chr22:39150450 G/A cg06022373 chr22:39101656 GTPBP1 0.76 7.12 0.54 7.63e-11 Menopause (age at onset); TGCT cis rs7226408 0.802 rs72892528 chr18:34673014 C/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs8077889 0.917 rs72836556 chr17:41911824 G/T cg26893861 chr17:41843967 DUSP3 1.09 13.16 0.76 2.68e-25 Triglycerides; TGCT cis rs10504229 0.815 rs17805008 chr8:58160185 G/T cg08280861 chr8:58055591 NA 0.39 4.93 0.4 2.57e-6 Developmental language disorder (linguistic errors); TGCT cis rs9811920 0.609 rs704583 chr3:99643693 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.59 -6.77 -0.52 4.51e-10 Axial length; TGCT cis rs801193 1.000 rs17566701 chr7:66193183 T/C cg18876405 chr7:65276391 NA 0.38 5.83 0.46 4.4e-8 Aortic root size; TGCT cis rs10791097 0.694 rs7107595 chr11:130758556 C/T cg12179176 chr11:130786555 SNX19 0.83 10.44 0.68 1.05e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7618915 0.547 rs68021750 chr3:52624769 G/A cg07507251 chr3:52567010 NT5DC2 0.48 6.91 0.53 2.24e-10 Bipolar disorder; TGCT cis rs17270561 0.666 rs4712976 chr6:25842203 C/T cg16482183 chr6:26056742 HIST1H1C 0.58 4.45 0.37 1.89e-5 Iron status biomarkers; TGCT cis rs2012796 0.872 rs59397507 chr14:81821334 A/G cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs9902453 0.845 rs3115099 chr17:28019293 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs514406 0.755 rs10888754 chr1:53228751 C/G cg24675658 chr1:53192096 ZYG11B 0.75 8.77 0.62 1.18e-14 Monocyte count; TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.67 0.39 7.57e-6 Prudent dietary pattern; TGCT cis rs478304 0.651 rs948493 chr11:65552154 C/T cg27068330 chr11:65405492 SIPA1 -0.95 -9.42 -0.65 3.25e-16 Acne (severe); TGCT cis rs1799949 0.965 rs35521261 chr17:41313612 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs3820928 0.605 rs7560867 chr2:227780945 C/A cg11843606 chr2:227700838 RHBDD1 -0.51 -4.83 -0.4 3.89e-6 Pulmonary function; TGCT cis rs3751972 0.668 rs7218395 chr17:26241477 G/A cg02948944 chr17:26242737 NA 0.39 5.61 0.45 1.26e-7 Fractional exhaled nitric oxide (childhood); TGCT cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6952809 0.532 rs2023969 chr7:2449980 T/C cg23289794 chr7:2394357 EIF3B -0.81 -6.84 -0.52 3.19e-10 Multiple sclerosis; TGCT cis rs66569888 0.710 rs67005606 chr2:106876277 T/C cg15412446 chr2:106886593 NA -0.41 -4.47 -0.37 1.72e-5 Facial morphology (factor 23); TGCT cis rs6429082 0.755 rs291371 chr1:235693105 C/G cg26050004 chr1:235667680 B3GALNT2 0.62 5.88 0.47 3.48e-8 Adiposity; TGCT cis rs28386778 0.897 rs9915552 chr17:61869095 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.69 -0.39 7e-6 Prudent dietary pattern; TGCT cis rs6977660 0.714 rs12386623 chr7:19791875 A/G cg05791153 chr7:19748676 TWISTNB -0.88 -5.05 -0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs9911578 0.967 rs6503883 chr17:56917543 C/T cg05425664 chr17:57184151 TRIM37 -0.62 -6.18 -0.49 8.33e-9 Intelligence (multi-trait analysis); TGCT cis rs7586879 0.828 rs1077641 chr2:25123665 G/A cg01884057 chr2:25150051 NA 0.27 4.81 0.4 4.36e-6 Body mass index; TGCT cis rs651907 0.557 rs34624546 chr3:101374226 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs3015497 0.616 rs6572678 chr14:51090115 T/G cg04730355 chr14:51134070 SAV1 -0.64 -6.04 -0.48 1.64e-8 Mean platelet volume; TGCT cis rs10782582 0.609 rs72979226 chr1:76302222 C/A cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs28595532 0.920 rs112016126 chr4:119726528 C/T cg14228332 chr4:119757509 SEC24D 1.38 6.93 0.53 2.07e-10 Cannabis dependence symptom count; TGCT cis rs7617773 0.779 rs1045482 chr3:48312229 A/G cg11946769 chr3:48343235 NME6 0.74 6.92 0.53 2.09e-10 Coronary artery disease; TGCT cis rs9611565 0.568 rs5751159 chr22:42175365 G/A cg17554472 chr22:41940697 POLR3H 0.43 4.61 0.38 9.67e-6 Vitiligo; TGCT cis rs7000551 0.751 rs2461481 chr8:22382780 A/G cg12081754 chr8:22256438 SLC39A14 -0.28 -4.44 -0.37 1.96e-5 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs4072705 0.835 rs10122154 chr9:127559038 C/T cg13476313 chr9:127244764 NR5A1 0.3 4.99 0.41 1.96e-6 Menarche (age at onset); TGCT cis rs11644362 1.000 rs72782620 chr16:12987416 T/A cg06890432 chr16:12997467 SHISA9 -0.6 -6.49 -0.5 1.88e-9 Positive affect;Subjective well-being; TGCT cis rs10791097 0.694 rs1893017 chr11:130756253 C/T cg14779329 chr11:130786720 SNX19 0.29 4.94 0.41 2.45e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs8017423 0.967 rs60548738 chr14:90724399 G/A cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs2404602 1.000 rs2404740 chr15:76852143 C/T cg22467129 chr15:76604101 ETFA -0.58 -6.68 -0.51 7.09e-10 Blood metabolite levels; TGCT cis rs4285028 0.847 rs1986712 chr3:121710986 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.44 -0.5 2.36e-9 Multiple sclerosis; TGCT cis rs17539620 0.624 rs62432736 chr6:154834401 A/G cg20019720 chr6:154832845 CNKSR3 0.56 4.75 0.39 5.5e-6 Lipoprotein (a) levels; TGCT cis rs6089584 0.888 rs6061405 chr20:60617033 A/G cg06108461 chr20:60628389 TAF4 -0.69 -10.77 -0.7 1.71e-19 Body mass index; TGCT trans rs8073060 0.586 rs4796101 chr17:33998593 C/T cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs9858542 0.537 rs9864406 chr3:49352619 A/G cg00383909 chr3:49044727 WDR6 0.69 4.78 0.39 4.84e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs6570726 0.967 rs7772286 chr6:145930423 A/T cg23711669 chr6:146136114 FBXO30 -0.77 -7.57 -0.56 7.21e-12 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.547 rs2268026 chr3:52778347 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.49 -4.76 -0.39 5.34e-6 Bipolar disorder; TGCT cis rs9534288 0.671 rs4942465 chr13:46562687 C/T cg15192986 chr13:46630673 CPB2 -0.5 -7.03 -0.53 1.23e-10 Blood protein levels; TGCT cis rs7647973 1.000 rs56127630 chr3:49438036 C/G cg07636037 chr3:49044803 WDR6 -0.72 -5.79 -0.46 5.35e-8 Menarche (age at onset); TGCT cis rs12049671 0.530 rs11018412 chr10:129747902 A/G cg22891191 chr10:129706234 PTPRE -0.34 -5.03 -0.41 1.66e-6 Response to amphetamines; TGCT cis rs4820539 0.932 rs3788349 chr22:23467950 A/G cg21100191 chr22:23484243 RTDR1 0.88 10.0 0.67 1.28e-17 Bone mineral density; TGCT cis rs7659604 0.605 rs1507994 chr4:122749541 C/T cg19748678 chr4:122722346 EXOSC9 0.8 8.14 0.59 3.52e-13 Type 2 diabetes; TGCT cis rs28386778 0.933 rs2665801 chr17:61952100 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.13 0.82 3.12e-32 Prudent dietary pattern; TGCT cis rs7772486 0.754 rs702319 chr6:146006117 T/C cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs10010698 chr4:98981594 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.84 0.46 4.35e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7805747 1.000 rs10480299 chr7:151405818 A/G cg17611936 chr7:151411526 PRKAG2 0.51 6.56 0.51 1.32e-9 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs9330316 0.588 rs28567471 chr2:110306425 A/G cg25199208 chr2:109402912 CCDC138 -0.42 -4.52 -0.38 1.42e-5 Schizophrenia; TGCT cis rs11578119 0.933 rs35227427 chr1:170468472 G/A cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs4819052 0.959 rs8130866 chr21:46672112 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.99 8.01 0.58 7.16e-13 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9858542 1.000 rs6770670 chr3:49686682 T/C cg03060546 chr3:49711283 APEH -0.67 -6.09 -0.48 1.28e-8 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7267979 1.000 rs7020 chr20:25278600 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs854572 0.600 rs705382 chr7:94955221 C/G cg17330251 chr7:94953956 PON1 -0.52 -6.93 -0.53 2.05e-10 Paraoxonase activity; TGCT cis rs9926296 0.712 rs258319 chr16:89732024 A/T cg27121462 chr16:89883253 FANCA -0.54 -4.87 -0.4 3.38e-6 Vitiligo; TGCT cis rs10927875 0.864 rs12135073 chr1:16167799 C/T cg21385522 chr1:16154831 NA 0.77 10.36 0.68 1.69e-18 Dilated cardiomyopathy; TGCT cis rs7959452 0.570 rs10878964 chr12:69720691 T/G cg20891283 chr12:69753455 YEATS4 0.66 6.6 0.51 1.08e-9 Blood protein levels; TGCT cis rs523522 0.962 rs10849753 chr12:120910813 C/T cg27279351 chr12:120934652 DYNLL1 0.78 6.7 0.52 6.57e-10 High light scatter reticulocyte count; TGCT cis rs1385374 0.858 rs3741615 chr12:129298848 G/A cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs1577917 0.771 rs12199873 chr6:86294947 C/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.58 -0.45 1.43e-7 Response to antipsychotic treatment; TGCT cis rs921968 0.541 rs7601872 chr2:219319885 C/G cg02176678 chr2:219576539 TTLL4 -0.49 -7.7 -0.57 3.81e-12 Mean corpuscular hemoglobin concentration; TGCT trans rs459571 0.920 rs417142 chr9:136891370 G/T cg09836344 chr4:1243392 C4orf42;CTBP1 -0.72 -7.8 -0.57 2.15e-12 Platelet distribution width; TGCT cis rs1577917 1.000 rs16876529 chr6:86591202 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.16 -0.42 9.71e-7 Response to antipsychotic treatment; TGCT cis rs7937682 0.924 rs495460 chr11:111504777 G/A cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs9436747 0.641 rs11208677 chr1:66048417 A/G cg14976592 chr1:65886160 LEPROT;LEPR 0.53 4.72 0.39 6.28e-6 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;White blood cell count;Granulocyte count;Neutrophil count;Myeloid white cell count; TGCT cis rs7178424 0.516 rs11632842 chr15:62329868 A/G cg00456672 chr15:62358751 C2CD4A -0.29 -4.48 -0.37 1.67e-5 Height; TGCT cis rs1552244 0.882 rs17050660 chr3:10001772 A/G cg18598329 chr3:10140678 FANCD2;C3orf24 0.46 6.37 0.5 3.31e-9 Alzheimer's disease; TGCT cis rs7618915 0.547 rs11720432 chr3:52672742 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs9910055 0.509 rs9916444 chr17:42313512 C/G cg13607699 chr17:42295918 UBTF 0.96 10.81 0.7 1.38e-19 Total body bone mineral density; TGCT cis rs1580019 0.587 rs34488151 chr7:32548146 A/G cg06627557 chr7:32535165 LSM5;AVL9 1.13 14.15 0.79 1.17e-27 Cognitive ability; TGCT cis rs736408 0.509 rs13083798 chr3:52649748 A/G cg10802521 chr3:52805072 NEK4 -0.69 -8.25 -0.6 1.98e-13 Bipolar disorder; TGCT cis rs9611565 0.659 rs1810461 chr22:41927820 G/A cg13695892 chr22:41940480 POLR3H -0.91 -9.07 -0.63 2.18e-15 Vitiligo; TGCT cis rs3820068 0.705 rs11584209 chr1:15885041 G/T cg05660106 chr1:15850417 CASP9 1.15 13.74 0.78 1.14e-26 Systolic blood pressure; TGCT cis rs7829975 0.606 rs6601274 chr8:8799059 T/G cg15556689 chr8:8085844 FLJ10661 -0.72 -6.22 -0.49 6.91e-9 Mood instability; TGCT cis rs79349575 0.783 rs62075818 chr17:46982327 T/A cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT trans rs7613875 0.580 rs11709503 chr3:49991167 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.8 8.32 0.6 1.31e-13 Body mass index; TGCT cis rs6570726 0.764 rs1912023 chr6:145824278 C/A cg23711669 chr6:146136114 FBXO30 0.89 9.72 0.66 6.02e-17 Lobe attachment (rater-scored or self-reported); TGCT trans rs17684571 0.938 rs10498811 chr6:56561273 T/C cg14229071 chr15:89282588 NA 0.51 6.79 0.52 4.04e-10 Schizophrenia; TGCT cis rs9818758 0.607 rs80170003 chr3:48951640 T/C cg07636037 chr3:49044803 WDR6 -1.01 -4.87 -0.4 3.34e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2235642 0.750 rs2859310 chr16:1656765 C/T cg07639376 chr16:1584516 IFT140;TMEM204 0.29 4.93 0.4 2.6e-6 Coronary artery disease; TGCT cis rs35306767 0.903 rs11813210 chr10:919796 G/A cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs9611565 0.512 rs132767 chr22:42009520 C/T cg06481639 chr22:41940642 POLR3H -0.7 -6.22 -0.49 6.96e-9 Vitiligo; TGCT cis rs4851266 1.000 rs6750097 chr2:100836885 T/C cg22139774 chr2:100720529 AFF3 -0.34 -5.09 -0.42 1.28e-6 Educational attainment; TGCT cis rs826838 0.967 rs1352123 chr12:39130992 T/C cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs9467711 0.559 rs3799383 chr6:26510748 C/T cg16898833 chr6:26189333 HIST1H4D 1.01 5.1 0.42 1.21e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs931127 0.719 rs2170082 chr11:65454795 A/G cg17480646 chr11:65405466 SIPA1 -0.44 -5.73 -0.46 7.24e-8 Systemic lupus erythematosus; TGCT cis rs17253792 0.731 rs74829671 chr14:56112759 G/C cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs1362404 0.614 rs9925381 chr16:51959612 A/C cg03955530 chr16:52681474 NA 0.29 4.5 0.37 1.53e-5 Gut microbiota (bacterial taxa); TGCT cis rs1385374 0.698 rs2170988 chr12:129290876 A/C cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs4665809 1.000 rs6546728 chr2:26276531 G/C cg25036284 chr2:26402008 FAM59B -0.57 -4.99 -0.41 2e-6 Gut microbiome composition (summer); TGCT cis rs6951245 0.744 rs1133122 chr7:1192572 C/A cg23708337 chr7:1209742 NA 0.63 6.03 0.48 1.78e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs6921919 0.583 rs13437294 chr6:28341535 C/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.37 -0.43 3.8e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4727027 0.716 rs4727020 chr7:148837317 C/T cg15662616 chr7:148823355 ZNF425;ZNF398 0.57 4.72 0.39 6.24e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs6666258 1.000 rs11588763 chr1:154813584 C/T cg06418219 chr1:154948305 SHC1;CKS1B 0.61 4.96 0.41 2.26e-6 Atrial fibrillation; TGCT cis rs858239 0.799 rs10279941 chr7:23370508 C/G cg05602783 chr7:23145260 KLHL7 -0.7 -5.82 -0.46 4.83e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs6674176 0.935 rs4314918 chr1:44377503 G/A cg12908607 chr1:44402522 ARTN -0.74 -8.71 -0.62 1.58e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7655441 0.963 rs11543549 chr4:80909952 G/T cg02241357 chr4:80885279 ANTXR2 -0.23 -4.52 -0.38 1.45e-5 Neutrophil percentage of white cells; TGCT cis rs36051895 0.632 rs10115335 chr9:5140963 A/T cg02405213 chr9:5042618 JAK2 -0.74 -10.39 -0.68 1.4e-18 Pediatric autoimmune diseases; TGCT cis rs55794721 0.509 rs11249248 chr1:25753051 T/C cg00786635 chr1:25594202 NA 0.57 5.96 0.47 2.4e-8 Plateletcrit;Mean corpuscular volume; TGCT cis rs10791097 0.694 rs10791103 chr11:130757161 G/A cg05962950 chr11:130786565 SNX19 0.92 11.77 0.73 6.29e-22 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7264396 0.635 rs6058366 chr20:34512172 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs981844 0.712 rs2405208 chr4:154755774 T/C cg14289246 chr4:154710475 SFRP2 -0.96 -8.97 -0.63 3.91e-15 Response to statins (LDL cholesterol change); TGCT cis rs10883723 0.810 rs3740406 chr10:104272789 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs72945132 0.882 rs56176527 chr11:70162513 A/G cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs910316 0.737 rs175049 chr14:75481368 C/T cg08847533 chr14:75593920 NEK9 -0.84 -8.92 -0.63 5.19e-15 Height; TGCT cis rs1862618 0.853 rs1559282 chr5:56099375 T/A cg12311346 chr5:56204834 C5orf35 -0.63 -6.36 -0.5 3.5e-9 Initial pursuit acceleration; TGCT cis rs9534288 0.731 rs2404730 chr13:46617381 G/A cg15192986 chr13:46630673 CPB2 -0.5 -7.06 -0.54 1.07e-10 Blood protein levels; TGCT cis rs13108904 0.870 rs3755927 chr4:1238246 G/A cg03303774 chr4:1407052 NA 0.28 4.57 0.38 1.16e-5 Obesity-related traits; TGCT cis rs3026101 0.671 rs1806222 chr17:5289676 C/T cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.57 0.38 1.16e-5 Body mass index; TGCT cis rs28595532 0.841 rs114965278 chr4:119743694 T/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs1008375 1.000 rs13148861 chr4:17688338 G/A cg16339924 chr4:17578868 LAP3 -0.6 -4.76 -0.39 5.25e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs13394619 0.565 rs12478958 chr2:11748037 A/G cg07314298 chr2:11723111 GREB1 -0.29 -4.94 -0.41 2.46e-6 Endometriosis; TGCT cis rs1205863 1.000 rs1205887 chr6:11948136 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs11096990 0.634 rs2381372 chr4:39273091 A/C cg20847110 chr4:39482781 LOC401127 0.16 4.55 0.38 1.26e-5 Cognitive function; TGCT cis rs7085104 0.572 rs284856 chr10:104574329 A/T cg05855489 chr10:104503620 C10orf26 -0.63 -6.21 -0.49 7.3e-9 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs9303401 0.659 rs35082010 chr17:56936867 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs765787 0.530 rs11070451 chr15:45533541 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs9372498 0.536 rs13437605 chr6:118899014 C/T cg07617317 chr6:118971624 C6orf204 0.5 5.32 0.43 4.71e-7 Diastolic blood pressure; TGCT cis rs9309473 0.687 rs6710659 chr2:73607510 A/G cg20560298 chr2:73613845 ALMS1 -0.44 -4.81 -0.4 4.23e-6 Metabolite levels; TGCT cis rs7267979 0.816 rs405822 chr20:25501314 A/G cg03522245 chr20:25566470 NINL 0.56 5.79 0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3099143 0.522 rs2469227 chr15:77281830 C/G cg22256960 chr15:77711686 NA 0.71 4.49 0.37 1.58e-5 Recalcitrant atopic dermatitis; TGCT cis rs9467773 0.565 rs6925047 chr6:26521435 C/G cg09904177 chr6:26538194 HMGN4 0.5 4.76 0.39 5.25e-6 Intelligence (multi-trait analysis); TGCT cis rs57024841 0.562 rs7862602 chr9:139840471 G/T cg00693599 chr9:139836323 FBXW5 0.22 4.79 0.4 4.62e-6 Beta-trace protein levels; TGCT cis rs1865760 0.566 rs9358904 chr6:26068566 C/T cg16482183 chr6:26056742 HIST1H1C 0.54 4.54 0.38 1.32e-5 Height; TGCT cis rs548987 0.529 rs1165164 chr6:25863481 G/A cg12310025 chr6:25882481 NA -0.65 -5.4 -0.44 3.31e-7 Homocysteine levels; TGCT cis rs951366 0.789 rs1775154 chr1:205696615 T/A cg07157834 chr1:205819609 PM20D1 0.43 7.03 0.53 1.25e-10 Menarche (age at onset); TGCT cis rs7267979 0.816 rs409853 chr20:25506067 T/C cg16686733 chr20:25566563 NINL 0.52 5.05 0.41 1.52e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4975709 0.589 rs4975745 chr5:1861058 G/C cg04156016 chr5:1868137 NA 0.33 4.66 0.39 8.06e-6 Cardiovascular disease risk factors; TGCT cis rs1218582 0.774 rs2335409 chr1:154916106 G/A cg09359103 chr1:154839909 KCNN3 -0.72 -14.91 -0.8 1.93e-29 Prostate cancer; TGCT cis rs56235845 0.694 rs11749830 chr5:176766547 G/A cg17509989 chr5:176798049 RGS14 0.57 7.78 0.57 2.49e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs2688608 0.868 rs2688625 chr10:75631548 T/C cg19442545 chr10:75533431 FUT11 -0.31 -5.04 -0.41 1.61e-6 Inflammatory bowel disease; TGCT cis rs7760949 0.963 rs1330117 chr6:13920926 C/T cg27413430 chr6:13925136 RNF182 0.6 5.72 0.46 7.41e-8 Mean corpuscular hemoglobin concentration; TGCT cis rs4665809 1.000 rs11126364 chr2:26314515 A/G cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs1972863 0.915 rs1972860 chr4:94579640 C/T cg20305610 chr4:95373302 PDLIM5 -0.52 -4.55 -0.38 1.24e-5 Intelligence (multi-trait analysis); TGCT cis rs2034088 0.833 rs7219151 chr17:440497 G/A cg06217071 chr17:408420 NA 0.35 5.27 0.43 5.75e-7 Hip circumference adjusted for BMI; TGCT cis rs9560113 1.000 rs61967684 chr13:112178026 G/C cg14154082 chr13:112174009 NA 0.37 5.07 0.41 1.42e-6 Menarche (age at onset); TGCT cis rs6840360 0.615 rs10001603 chr4:152647577 T/A cg22705602 chr4:152727874 NA -0.34 -5.83 -0.46 4.4e-8 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.545 rs11700449 chr21:40522419 A/T cg06238570 chr21:40685208 BRWD1 -0.6 -6.19 -0.49 7.97e-9 Menarche (age at onset); TGCT cis rs2243480 1.000 rs4718309 chr7:65627764 G/C cg20637647 chr7:64974828 NA -0.9 -5.31 -0.43 4.87e-7 Diabetic kidney disease; TGCT cis rs11577318 0.796 rs4625269 chr1:26626967 C/A cg04990556 chr1:26633338 UBXN11 -0.62 -5.76 -0.46 6.33e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs7611238 0.560 rs6437471 chr3:195051895 A/G cg27323046 chr3:195102265 ACAP2 0.36 4.81 0.4 4.35e-6 Body mass index; TGCT cis rs651907 0.535 rs17412601 chr3:101499275 T/C cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.51 4.86 0.4 3.51e-6 Colorectal cancer; TGCT trans rs17685 0.753 rs1104879 chr7:75685568 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 8.84 0.62 7.72e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs17376456 0.877 rs9885329 chr5:93380278 G/A cg21475434 chr5:93447410 FAM172A 0.6 4.62 0.38 9.48e-6 Diabetic retinopathy; TGCT cis rs873946 0.557 rs34854637 chr10:134582962 A/G cg26118208 chr10:134322334 NA 0.24 4.59 0.38 1.07e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs1862618 0.853 rs252902 chr5:56116085 A/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.86 -0.52 2.83e-10 Initial pursuit acceleration; TGCT cis rs6546537 0.824 rs55864699 chr2:69803650 C/T cg10773587 chr2:69614142 GFPT1 -0.76 -6.88 -0.53 2.6e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs12220238 0.915 rs11001014 chr10:76128832 A/G cg19889307 chr10:75911429 ADK;AP3M1 -0.91 -6.27 -0.49 5.54e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9388451 0.839 rs1811852 chr6:126071575 G/C cg05901451 chr6:126070800 HEY2 -1.04 -15.8 -0.82 1.76e-31 Brugada syndrome; TGCT trans rs941408 1.000 rs759068 chr19:2792566 G/A cg22153745 chr1:153894579 GATAD2B -0.64 -7.26 -0.55 3.67e-11 Total cholesterol levels; TGCT cis rs4478037 0.731 rs9835090 chr3:33107671 G/T cg19404215 chr3:33155277 CRTAP 0.91 4.72 0.39 6.24e-6 Major depressive disorder; TGCT cis rs7605378 1.000 rs2577852 chr2:200687248 C/T cg23649088 chr2:200775458 C2orf69 0.35 5.83 0.46 4.53e-8 Osteoporosis; TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg14820908 chr5:178986412 RUFY1 0.49 4.95 0.41 2.35e-6 Lung cancer; TGCT cis rs1799949 1.000 rs11653460 chr17:41331306 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.47 4.89 0.4 3e-6 Menopause (age at onset); TGCT cis rs1801251 1.000 rs13035829 chr2:233604487 A/T cg08000102 chr2:233561755 GIGYF2 0.64 6.45 0.5 2.22e-9 Coronary artery disease; TGCT cis rs11792861 0.781 rs28361152 chr9:111727529 T/C cg14432460 chr9:111696404 IKBKAP;C9orf6 0.53 4.96 0.41 2.24e-6 Menarche (age at onset); TGCT cis rs3796619 1.000 rs12647929 chr4:1092019 G/T cg27284194 chr4:1044797 NA 0.47 4.57 0.38 1.17e-5 Recombination rate (males); TGCT cis rs1532993 0.500 rs12509721 chr4:98554525 C/A cg05340658 chr4:99064831 C4orf37 -0.42 -5.05 -0.41 1.57e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs2070488 0.662 rs6599203 chr3:38487802 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.66 5.14 0.42 1.02e-6 Electrocardiographic conduction measures; TGCT cis rs17384381 0.834 rs11161614 chr1:85898160 A/C cg16011679 chr1:85725395 C1orf52 0.8 6.4 0.5 2.84e-9 Lobe attachment (rater-scored or self-reported); TGCT trans rs208520 0.526 rs9354366 chr6:66788559 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.09 -16.9 -0.84 5.6e-34 Exhaled nitric oxide output; TGCT cis rs2292884 0.505 rs77856818 chr2:238402830 G/A cg14458575 chr2:238380390 NA 0.56 5.13 0.42 1.08e-6 Prostate cancer; TGCT cis rs2243480 1.000 rs68189316 chr7:65409169 C/G cg20637647 chr7:64974828 NA 0.92 5.36 0.43 3.87e-7 Diabetic kidney disease; TGCT cis rs7845219 0.555 rs1129152 chr8:95888307 C/T cg16049864 chr8:95962084 TP53INP1 -0.66 -7.88 -0.58 1.43e-12 Type 2 diabetes; TGCT cis rs7312933 0.501 rs3810793 chr12:42729407 C/T cg19980929 chr12:42632907 YAF2 0.43 5.99 0.47 2.11e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs11874712 0.507 rs7239525 chr18:43654033 C/T cg20479805 chr18:43684716 ATP5A1;HAUS1 0.51 4.98 0.41 2.09e-6 Migraine - clinic-based; TGCT cis rs223116 1.000 rs223116 chr14:23977010 A/G cg11790074 chr14:23573850 NA -0.25 -4.48 -0.37 1.68e-5 Resting heart rate; TGCT cis rs2361718 0.631 rs2289539 chr17:78152119 T/C cg09238746 chr17:78121135 EIF4A3 -0.77 -7.22 -0.54 4.52e-11 Yeast infection; TGCT cis rs9926296 0.712 rs258319 chr16:89732024 A/T cg01097406 chr16:89675127 NA 0.36 6.31 0.49 4.55e-9 Vitiligo; TGCT cis rs9467773 0.620 rs2494701 chr6:26634432 C/T cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs11190604 1.000 rs2489034 chr10:102319192 C/T cg16342193 chr10:102329863 NA -0.39 -5.0 -0.41 1.92e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6546537 1.000 rs4286306 chr2:69885647 G/C cg10773587 chr2:69614142 GFPT1 -0.68 -6.1 -0.48 1.27e-8 Serum thyroid-stimulating hormone levels; TGCT cis rs477895 0.938 rs28395875 chr11:64024048 G/C cg04317338 chr11:64019027 PLCB3 0.71 5.75 0.46 6.48e-8 Mean platelet volume; TGCT cis rs9915657 0.773 rs9894696 chr17:70099487 C/T cg06234051 chr17:70120541 SOX9 -0.27 -5.58 -0.45 1.44e-7 Thyroid hormone levels; TGCT cis rs4906332 1.000 rs35771849 chr14:103981942 A/G cg26031613 chr14:104095156 KLC1 -0.54 -4.67 -0.39 7.66e-6 Coronary artery disease; TGCT cis rs9828933 0.577 rs832194 chr3:63857071 G/A cg16258503 chr3:63850278 ATXN7;THOC7 0.75 4.52 0.38 1.4e-5 Type 2 diabetes; TGCT cis rs2032447 0.517 rs7767546 chr6:25904067 T/C cg15691649 chr6:25882328 NA -0.47 -5.32 -0.43 4.61e-7 Intelligence (multi-trait analysis); TGCT cis rs2153535 0.601 rs9505472 chr6:8538765 T/C cg07606381 chr6:8435919 SLC35B3 0.55 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs698833 0.548 rs6721421 chr2:44535686 G/A cg23552047 chr2:44669647 C2orf34 0.29 4.68 0.39 7.32e-6 antipsychotic drug dosage in schizophrenia or schizoaffective disorder; TGCT cis rs801193 1.000 rs2707856 chr7:66211010 A/T cg18876405 chr7:65276391 NA 0.36 5.37 0.43 3.81e-7 Aortic root size; TGCT cis rs877282 0.947 rs957642 chr10:773966 C/T cg17470449 chr10:769945 NA 0.3 4.77 0.39 5.05e-6 Uric acid levels; TGCT cis rs78487399 0.710 rs7590220 chr2:43702151 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -5.45 -0.44 2.63e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs11711311 1.000 rs62268168 chr3:113489447 A/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.79 -7.32 -0.55 2.75e-11 IgG glycosylation; TGCT cis rs17376456 0.825 rs10078941 chr5:93279029 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs3087591 0.881 rs2905804 chr17:29519995 T/C cg24425628 chr17:29625626 OMG;NF1 0.42 6.22 0.49 7.06e-9 Hip circumference; TGCT cis rs72781680 0.821 rs56064672 chr2:24156769 G/T cg08917208 chr2:24149416 ATAD2B 0.74 4.66 0.39 7.9e-6 Lymphocyte counts; TGCT cis rs4523957 0.620 rs8070272 chr17:2063117 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9660180 0.934 rs12729990 chr1:1812035 T/A cg13866156 chr1:1669148 SLC35E2 -0.21 -5.12 -0.42 1.16e-6 Body mass index; TGCT cis rs17490626 0.568 rs12413525 chr10:71211721 C/A cg12610070 chr10:71211762 TSPAN15 -0.62 -7.15 -0.54 6.52e-11 Thrombosis; TGCT cis rs9467711 0.606 rs9379858 chr6:26367689 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6964587 1.000 rs35317449 chr7:91637010 G/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs11711311 1.000 rs9863050 chr3:113508888 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.07 -0.54 1.01e-10 IgG glycosylation; TGCT cis rs2120019 1.000 rs35577967 chr15:75354621 G/A cg11632617 chr15:75315747 PPCDC -0.33 -4.59 -0.38 1.07e-5 Blood trace element (Zn levels); TGCT cis rs7945705 0.967 rs10840141 chr11:8902218 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.43 4.85 0.4 3.56e-6 Hemoglobin concentration; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg04234412 chr22:24373322 LOC391322 -0.91 -10.58 -0.69 4.78e-19 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467773 0.620 rs2504565 chr6:26656890 G/A cg15659132 chr6:26577336 NA 0.87 10.67 0.69 2.97e-19 Intelligence (multi-trait analysis); TGCT cis rs317689 0.819 rs317677 chr12:69691806 G/A cg14784868 chr12:69753453 YEATS4 0.57 4.9 0.4 2.96e-6 Response to diuretic therapy; TGCT cis rs9611565 0.918 rs7290404 chr22:41749796 C/T cg17554472 chr22:41940697 POLR3H -0.5 -5.25 -0.43 6.29e-7 Vitiligo; TGCT cis rs951366 0.789 rs864783 chr1:205711974 T/C cg14159672 chr1:205819179 PM20D1 0.61 7.57 0.56 7.33e-12 Menarche (age at onset); TGCT cis rs4689388 0.856 rs1046314 chr4:6303955 A/G cg00701064 chr4:6280414 WFS1 -0.43 -5.63 -0.45 1.17e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs554111 0.891 rs659046 chr1:21047725 C/T cg08890418 chr1:21044141 KIF17 -0.57 -6.26 -0.49 5.62e-9 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs6674176 0.597 rs9326136 chr1:44390392 A/G cg12908607 chr1:44402522 ARTN 0.74 9.09 0.63 1.99e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7412746 0.658 rs2275235 chr1:150730279 A/G cg09365446 chr1:150670422 GOLPH3L 0.35 5.08 0.42 1.33e-6 Melanoma; TGCT cis rs2180341 0.814 rs6569488 chr6:127726256 C/T cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs7429990 0.965 rs35012836 chr3:47711490 G/A cg11946769 chr3:48343235 NME6 0.59 4.45 0.37 1.91e-5 Educational attainment (years of education); TGCT cis rs2562456 0.833 rs552800 chr19:21484642 G/A cg01304269 chr19:21688519 ZNF429 -0.55 -4.47 -0.37 1.76e-5 Pain; TGCT cis rs7909074 1.000 rs12777258 chr10:45394961 A/G cg04218760 chr10:45406644 TMEM72 0.27 5.54 0.45 1.76e-7 Mean corpuscular volume; TGCT cis rs6500602 0.727 rs10451135 chr16:4580214 T/C cg08645402 chr16:4508243 NA 0.19 5.3 0.43 5.14e-7 Schizophrenia; TGCT cis rs2235642 0.893 rs2076440 chr16:1587322 G/A cg10465839 chr16:1584050 IFT140;TMEM204 -0.32 -5.23 -0.43 6.98e-7 Coronary artery disease; TGCT cis rs868036 0.718 rs4776985 chr15:68123021 T/G cg05925327 chr15:68127851 NA -0.51 -5.04 -0.41 1.63e-6 Restless legs syndrome; TGCT cis rs36051895 0.623 rs2146041 chr9:5262911 A/G cg02405213 chr9:5042618 JAK2 -0.68 -8.17 -0.59 3e-13 Pediatric autoimmune diseases; TGCT cis rs9790314 0.846 rs7627528 chr3:160990878 A/G cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs765787 0.530 rs1706830 chr15:45516229 G/A cg24006582 chr15:45444508 DUOX1 -0.26 -5.62 -0.45 1.19e-7 Uric acid levels; TGCT trans rs10506458 0.915 rs17738485 chr12:63394932 T/C cg22491629 chr6:157744540 C6orf35 -0.99 -8.55 -0.61 3.94e-14 Hemostatic factors and hematological phenotypes; TGCT cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT cis rs3845624 0.610 rs3027044 chr1:159181869 C/T cg07961479 chr1:159825173 VSIG8;C1orf204 0.23 4.55 0.38 1.28e-5 Inflammatory biomarkers; TGCT cis rs539096 0.918 rs519669 chr1:44075505 G/C cg12908607 chr1:44402522 ARTN -0.53 -5.61 -0.45 1.26e-7 Intelligence (multi-trait analysis); TGCT cis rs2932538 0.922 rs3790612 chr1:113084146 G/A cg22162597 chr1:113214053 CAPZA1 0.28 6.0 0.47 2.02e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs514406 0.825 rs487453 chr1:53271225 T/C cg24675658 chr1:53192096 ZYG11B 0.75 8.79 0.62 1.05e-14 Monocyte count; TGCT cis rs17270561 0.562 rs74293932 chr6:26014811 C/A cg17691542 chr6:26056736 HIST1H1C 1.0 7.07 0.54 9.94e-11 Iron status biomarkers; TGCT cis rs2066819 0.892 rs112931321 chr12:56667894 C/T cg26714650 chr12:56694279 CS -1.36 -6.06 -0.48 1.54e-8 Psoriasis vulgaris; TGCT cis rs67073037 0.955 rs4666144 chr2:29174105 C/T cg09522027 chr2:28974177 PPP1CB 0.58 4.62 0.38 9.63e-6 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs6540559 0.673 rs11803382 chr1:209986426 G/A cg23283495 chr1:209979779 IRF6 0.65 5.04 0.41 1.63e-6 Cleft lip with or without cleft palate; TGCT cis rs57221529 0.766 rs72703042 chr5:579269 C/T cg09021430 chr5:549028 NA -0.37 -5.16 -0.42 9.7e-7 Lung disease severity in cystic fibrosis; TGCT cis rs4285028 0.948 rs71329247 chr3:121681523 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.55 -0.51 1.35e-9 Multiple sclerosis; TGCT cis rs2692947 0.644 rs1168970 chr2:96816606 C/T cg23100626 chr2:96804247 ASTL 0.46 5.42 0.44 3.03e-7 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs739496 0.579 rs80017658 chr12:112380372 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs9527 0.590 rs11191544 chr10:104827198 C/G cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.62e-7 Arsenic metabolism; TGCT cis rs736408 1.000 rs2710331 chr3:52837855 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.64 0.38 8.84e-6 Bipolar disorder; TGCT cis rs28595532 0.920 rs114584210 chr4:119773363 G/A cg11846333 chr4:119757529 SEC24D 0.9 4.57 0.38 1.18e-5 Cannabis dependence symptom count; TGCT cis rs988712 0.672 rs12419948 chr11:27666984 T/A cg10635145 chr11:27742435 BDNF -0.38 -5.25 -0.43 6.38e-7 Obesity; TGCT cis rs919433 0.679 rs10166328 chr2:198511917 A/G cg00792783 chr2:198669748 PLCL1 0.56 5.03 0.41 1.68e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs854765 0.583 rs67253360 chr17:17828973 T/C cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.16e-6 Total body bone mineral density; TGCT cis rs17433780 0.897 rs12120863 chr1:89501522 T/C cg09516651 chr1:89888402 LOC400759 0.26 4.48 0.37 1.67e-5 Carotid intima media thickness; TGCT cis rs9341808 0.718 rs9343978 chr6:80971978 A/G cg08355045 chr6:80787529 NA 0.29 4.98 0.41 2.04e-6 Sitting height ratio; TGCT cis rs5769707 0.667 rs4824069 chr22:50030325 T/C cg06623630 chr22:50017776 C22orf34 -0.27 -4.7 -0.39 6.81e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9916302 0.904 rs600010 chr17:37433517 T/C cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.77e-6 Glomerular filtration rate (creatinine); TGCT cis rs62055045 0.656 rs112777805 chr16:71425165 G/C cg09204302 chr16:70713462 MTSS1L -0.31 -4.94 -0.41 2.51e-6 Schizophrenia; TGCT cis rs7666738 0.830 rs6840766 chr4:99016260 C/G cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs2836974 0.899 rs34176878 chr21:40548855 C/A cg11890956 chr21:40555474 PSMG1 1.14 12.22 0.74 4.93e-23 Cognitive function; TGCT cis rs7428 0.527 rs4832164 chr2:85546932 A/C cg03728395 chr2:85555865 TGOLN2 -0.31 -5.27 -0.43 5.85e-7 Ear protrusion; TGCT cis rs1153858 1.000 rs66939267 chr15:45676902 T/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs2361718 0.501 rs8065486 chr17:78138196 A/G cg21238619 chr17:78079768 GAA 0.33 4.66 0.39 7.96e-6 Yeast infection; TGCT cis rs1801251 1.000 rs7606090 chr2:233606740 T/C cg08000102 chr2:233561755 GIGYF2 0.64 6.45 0.5 2.22e-9 Coronary artery disease; TGCT cis rs2933343 0.553 rs789212 chr3:128686912 A/C cg11901034 chr3:128598214 ACAD9 -0.56 -5.26 -0.43 6.06e-7 IgG glycosylation; TGCT cis rs6089829 0.632 rs62197308 chr20:61660705 T/C cg03213289 chr20:61660250 NA -0.51 -5.59 -0.45 1.38e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2739330 0.796 rs2154594 chr22:24254055 A/G cg12419862 chr22:24373484 LOC391322 0.8 8.5 0.61 5.17e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs57590327 0.527 rs7610703 chr3:81613942 G/A cg07356753 chr3:81810745 GBE1 -0.59 -4.96 -0.41 2.23e-6 Extraversion; TGCT cis rs28386778 0.897 rs6504185 chr17:61848792 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT cis rs12142240 0.738 rs41293277 chr1:46806550 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.78 -0.39 4.78e-6 Menopause (age at onset); TGCT cis rs7659604 0.502 rs13108419 chr4:122687238 A/G cg19748678 chr4:122722346 EXOSC9 -0.57 -5.58 -0.45 1.41e-7 Type 2 diabetes; TGCT cis rs12216125 0.554 rs6942196 chr6:26072804 A/G cg16482183 chr6:26056742 HIST1H1C 0.58 4.97 0.41 2.19e-6 Iron status biomarkers; TGCT cis rs9443189 0.526 rs10943250 chr6:76208445 C/G cg01950844 chr6:76311363 SENP6 0.91 5.52 0.44 1.89e-7 Prostate cancer; TGCT cis rs9926296 0.712 rs2434872 chr16:89716915 C/G cg26513180 chr16:89883248 FANCA -0.68 -6.33 -0.49 4.16e-9 Vitiligo; TGCT cis rs28595532 0.920 rs6818519 chr4:119787820 G/T cg14228332 chr4:119757509 SEC24D 1.19 6.66 0.51 8.07e-10 Cannabis dependence symptom count; TGCT cis rs1385374 0.858 rs10847698 chr12:129300222 T/C cg09035930 chr12:129282057 SLC15A4 -0.55 -4.76 -0.39 5.27e-6 Systemic lupus erythematosus; TGCT cis rs739401 0.611 rs391188 chr11:3047634 G/A cg05729581 chr11:3078854 CARS -0.53 -4.94 -0.41 2.51e-6 Longevity; TGCT cis rs3796352 1.000 rs6445557 chr3:53083969 C/T cg15956490 chr3:53032818 SFMBT1 -0.53 -6.27 -0.49 5.56e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs8177253 1.000 rs8177248 chr3:133479626 C/T cg11941060 chr3:133502564 NA -0.28 -5.58 -0.45 1.47e-7 Iron status biomarkers; TGCT cis rs6964587 0.839 rs62466159 chr7:91450507 A/G cg17063962 chr7:91808500 NA 0.83 8.41 0.6 8.35e-14 Breast cancer; TGCT cis rs908922 0.887 rs4596895 chr1:152528075 T/G cg20991723 chr1:152506922 NA 0.41 5.18 0.42 8.76e-7 Hair morphology; TGCT cis rs644799 1.000 rs518919 chr11:95623313 G/C cg03916912 chr11:95522834 CEP57;FAM76B 0.83 9.35 0.64 4.64e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7044106 0.708 rs991121 chr9:123370345 C/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.58 6.31 0.49 4.56e-9 Hip circumference adjusted for BMI; TGCT cis rs694739 0.657 rs11231770 chr11:64140625 G/A cg23796481 chr11:64053134 BAD;GPR137 0.63 6.54 0.51 1.44e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs4237845 0.967 rs4553410 chr12:58301211 G/A cg02175503 chr12:58329896 NA 0.51 5.09 0.42 1.3e-6 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.519 rs10880194 chr12:38302836 G/A cg26384229 chr12:38710491 ALG10B 0.82 7.18 0.54 5.6e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs1150688 1 rs1150688 chr6:28162780 T/C cg13525197 chr6:28411240 ZSCAN23 -0.48 -4.71 -0.39 6.43e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs6701037 0.625 rs34270511 chr1:175128543 C/T cg00321850 chr1:175162397 KIAA0040 -0.42 -5.83 -0.46 4.61e-8 Alcohol dependence; TGCT cis rs3733585 0.588 rs6449154 chr4:9956404 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.7 -0.52 6.62e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2739330 0.761 rs5760176 chr22:24402321 A/G cg24846343 chr22:24311635 DDTL -0.22 -5.7 -0.46 8.24e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7975161 0.572 rs4964228 chr12:104572759 T/C cg25273343 chr12:104657179 TXNRD1 -0.44 -5.8 -0.46 5.27e-8 Toenail selenium levels; TGCT cis rs7618915 0.570 rs2336145 chr3:52629750 A/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs6952808 0.689 rs12670737 chr7:2046830 C/T cg22963979 chr7:1858916 MAD1L1 -0.47 -7.55 -0.56 8.09e-12 Bipolar disorder and schizophrenia; TGCT cis rs832540 0.966 rs33321 chr5:56206073 G/T cg12311346 chr5:56204834 C5orf35 -0.51 -5.51 -0.44 1.94e-7 Coronary artery disease; TGCT trans rs1005277 0.579 rs2474586 chr10:38418882 T/C cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs7954584 0.567 rs1720037 chr12:122382229 G/T cg22618164 chr12:122356400 WDR66 -0.63 -6.2 -0.49 7.55e-9 Mean corpuscular volume; TGCT cis rs425277 1.000 rs1401138 chr1:2063149 C/T cg24578937 chr1:2090814 PRKCZ 0.32 7.65 0.57 4.86e-12 Height; TGCT cis rs78487399 0.808 rs7564886 chr2:43733028 G/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.43 -4.84 -0.4 3.79e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs7582180 0.715 rs1866198 chr2:100917739 C/A cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.45e-6 Intelligence (multi-trait analysis); TGCT cis rs933688 1.000 rs6862125 chr5:90724598 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.08 9.5 0.65 2.02e-16 Smoking behavior; TGCT cis rs10504229 1.000 rs66870803 chr8:58180022 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs6495122 0.699 rs34862454 chr15:75101530 C/T cg10253484 chr15:75165896 SCAMP2 -0.68 -6.04 -0.48 1.63e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs74054849 0.717 rs74054799 chr1:15926350 C/T cg05660106 chr1:15850417 CASP9 0.86 4.47 0.37 1.71e-5 Alcoholic chronic pancreatitis; TGCT cis rs2847297 1.000 rs2847297 chr18:12797694 A/G cg23598886 chr18:12777645 NA -0.4 -4.73 -0.39 5.95e-6 Rheumatoid arthritis; TGCT cis rs17030434 0.607 rs3747522 chr4:154644929 G/A cg14289246 chr4:154710475 SFRP2 -0.82 -6.83 -0.52 3.3e-10 Electrocardiographic conduction measures; TGCT cis rs3820068 0.603 rs7536654 chr1:15989141 C/G cg05660106 chr1:15850417 CASP9 0.8 8.0 0.58 7.42e-13 Systolic blood pressure; TGCT cis rs151317012 1 rs151317012 chr4:106806194 C/T cg24545054 chr4:106630052 GSTCD;INTS12 1.01 4.61 0.38 9.83e-6 Post bronchodilator FEV1; TGCT cis rs9399135 0.967 rs3756799 chr6:135341011 A/G cg24558204 chr6:135376177 HBS1L 0.49 4.84 0.4 3.77e-6 Red blood cell count; TGCT cis rs11785400 0.793 rs34875149 chr8:143736131 G/A cg10596483 chr8:143751796 JRK 0.53 5.27 0.43 5.89e-7 Schizophrenia; TGCT cis rs6988636 1.000 rs10505430 chr8:124191933 A/G cg23067535 chr8:124195133 FAM83A 0.35 5.22 0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg03188948 chr7:1209495 NA 0.48 6.91 0.53 2.31e-10 Longevity;Endometriosis; TGCT cis rs7811142 1.000 rs1000215 chr7:100004543 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs9796 0.870 rs8023345 chr15:41338348 T/G cg18705301 chr15:41695430 NDUFAF1 -0.41 -5.41 -0.44 3.06e-7 Menopause (age at onset); TGCT cis rs11718455 0.767 rs6782500 chr3:43990260 A/G cg08738300 chr3:44038990 NA -0.75 -5.73 -0.46 7.13e-8 Coronary artery disease; TGCT cis rs10992471 0.518 rs4743876 chr9:95512216 C/G cg13798575 chr9:95087839 CENPP;NOL8 -0.54 -4.58 -0.38 1.1e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs1799949 0.965 rs4793230 chr17:41427403 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.41 4.48 0.37 1.67e-5 Menopause (age at onset); TGCT cis rs875971 0.862 rs4718377 chr7:66049678 C/T cg11764359 chr7:65958608 NA -0.55 -5.08 -0.42 1.34e-6 Aortic root size; TGCT cis rs68170813 0.652 rs7807154 chr7:107161391 T/G cg02696742 chr7:106810147 HBP1 -0.58 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs6714710 0.580 rs55886305 chr2:98495661 T/G cg26665480 chr2:98280029 ACTR1B 0.64 6.03 0.48 1.71e-8 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs6089584 0.927 rs2296081 chr20:60572663 G/T cg06108461 chr20:60628389 TAF4 -0.58 -8.56 -0.61 3.6e-14 Body mass index; TGCT cis rs7666738 0.830 rs1426668 chr4:98945585 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs289997 1.000 rs2960816 chr7:25585754 A/G cg14064488 chr7:26331273 SNX10 -0.34 -4.74 -0.39 5.83e-6 Breast cancer; TGCT cis rs7917772 0.503 rs7899576 chr10:104307504 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 8.21 0.59 2.44e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs950169 0.922 rs12911223 chr15:84831671 G/A cg12863693 chr15:85201151 NMB -0.41 -4.47 -0.37 1.77e-5 Schizophrenia; TGCT cis rs9902453 0.730 rs3794808 chr17:28531793 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.66 5.93 0.47 2.78e-8 Coffee consumption (cups per day); TGCT cis rs548181 0.736 rs540436 chr11:125512619 A/G cg03464685 chr11:125439445 EI24 1.11 8.13 0.59 3.76e-13 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs514406 0.861 rs2448792 chr1:53268313 T/C cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs4523957 0.583 rs9889861 chr17:2041369 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs6748734 1.000 rs11893118 chr2:241828308 C/G cg04034577 chr2:241836375 C2orf54 -0.42 -6.45 -0.5 2.23e-9 Urinary metabolites; TGCT cis rs9467773 0.869 rs742090 chr6:26415637 A/C cg07107628 chr6:27210934 NA 0.16 4.53 0.38 1.38e-5 Intelligence (multi-trait analysis); TGCT cis rs1670533 1.000 rs2100411 chr4:1074412 T/C cg27284194 chr4:1044797 NA 0.68 5.84 0.46 4.28e-8 Recombination rate (females); TGCT cis rs7647973 0.961 rs4955417 chr3:49298205 T/C cg07690219 chr3:49449608 TCTA;RHOA -0.55 -4.48 -0.37 1.68e-5 Menarche (age at onset); TGCT cis rs13064411 0.542 rs9874747 chr3:113221258 G/A cg18753928 chr3:113234510 CCDC52 -0.54 -4.58 -0.38 1.12e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs3791556 1.000 rs3791568 chr2:240115701 G/A cg03281426 chr2:240109471 HDAC4 0.28 4.46 0.37 1.82e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs12950390 0.853 rs12451815 chr17:45855956 A/G cg06532163 chr17:45867833 NA 0.34 5.32 0.43 4.73e-7 IgG glycosylation; TGCT cis rs2836974 0.836 rs1041440 chr21:40627325 C/T cg17971929 chr21:40555470 PSMG1 0.98 9.65 0.65 9.11e-17 Cognitive function; TGCT cis rs2657888 0.930 rs7312441 chr12:56941146 C/A cg23002907 chr12:56915593 RBMS2 -0.45 -6.07 -0.48 1.44e-8 Adiponectin levels; TGCT cis rs2739330 0.587 rs4820571 chr22:24242973 A/G cg01238044 chr22:24384105 GSTT1 -0.49 -4.5 -0.37 1.53e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs270601 0.633 rs4535443 chr5:131572561 A/G cg12564285 chr5:131593104 PDLIM4 0.37 4.44 0.37 1.98e-5 Acylcarnitine levels; TGCT cis rs17376456 0.825 rs72786702 chr5:93254656 A/C cg25358565 chr5:93447407 FAM172A 0.98 7.85 0.58 1.68e-12 Diabetic retinopathy; TGCT cis rs281408 0.559 rs281381 chr19:49214748 C/T cg13540341 chr19:49222985 MAMSTR -0.44 -6.58 -0.51 1.16e-9 Urinary metabolites (H-NMR features); TGCT cis rs873946 0.504 rs3829132 chr10:134579044 A/C cg26118208 chr10:134322334 NA 0.27 5.21 0.42 7.65e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7769051 0.711 rs7758531 chr6:133085302 T/C cg07930552 chr6:133119739 C6orf192 0.9 4.67 0.39 7.86e-6 Type 2 diabetes nephropathy; TGCT cis rs4851266 1.000 rs11693324 chr2:100827753 T/C cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.73e-7 Educational attainment; TGCT cis rs6582630 0.537 rs1949610 chr12:38387838 C/T cg13010199 chr12:38710504 ALG10B 0.59 4.64 0.38 8.86e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs9814567 0.896 rs13089566 chr3:134349710 G/C cg06109529 chr3:134205091 CEP63;ANAPC13 0.84 7.7 0.57 3.76e-12 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs6912958 0.559 rs445434 chr6:88041849 A/G cg04972856 chr6:88032051 C6orf162;GJB7 0.39 4.48 0.37 1.66e-5 Monocyte percentage of white cells; TGCT cis rs7829975 0.559 rs4841025 chr8:8603160 A/G cg06636001 chr8:8085503 FLJ10661 -0.58 -4.79 -0.39 4.72e-6 Mood instability; TGCT trans rs1814175 0.817 rs11040474 chr11:49708441 G/A cg15704280 chr7:45808275 SEPT13 -0.71 -8.23 -0.59 2.14e-13 Height; TGCT cis rs523522 0.923 rs3916065 chr12:120934624 A/C cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs1185460 0.934 rs10892328 chr11:118942654 T/A cg01677386 chr11:118938358 VPS11 -0.54 -4.54 -0.38 1.32e-5 Coronary artery disease; TGCT cis rs9291683 0.610 rs993172 chr4:10324361 G/T cg00071950 chr4:10020882 SLC2A9 0.45 4.77 0.39 5.03e-6 Bone mineral density; TGCT cis rs4242434 0.757 rs7005025 chr8:22519815 G/T cg03733263 chr8:22462867 KIAA1967 1.02 14.27 0.79 6.14e-28 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7226408 0.802 rs72885298 chr18:34452064 C/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs651907 0.557 rs3806654 chr3:101396529 G/C cg12386194 chr3:101231763 SENP7 0.51 5.04 0.41 1.61e-6 Colorectal cancer; TGCT cis rs826838 0.904 rs1554550 chr12:39208889 G/A cg26384229 chr12:38710491 ALG10B 0.98 8.78 0.62 1.07e-14 Heart rate; TGCT cis rs7666738 0.830 rs11947578 chr4:98930462 T/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs28595532 0.920 rs115320476 chr4:119759680 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs9549367 0.713 rs3024743 chr13:113821430 C/T cg00898013 chr13:113819073 PROZ -0.53 -6.77 -0.52 4.62e-10 Platelet distribution width; TGCT cis rs9913156 0.793 rs9436 chr17:4574751 T/A cg19197139 chr17:4613644 ARRB2 0.86 7.97 0.58 8.69e-13 Lymphocyte counts; TGCT cis rs7264396 0.635 rs3827030 chr20:34474947 C/T cg04508476 chr20:34239394 CPNE1;RBM12 0.29 4.97 0.41 2.18e-6 Total cholesterol levels; TGCT cis rs8054556 0.760 rs12598856 chr16:30029548 C/T cg06015834 chr16:30021696 DOC2A -0.27 -4.5 -0.37 1.56e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs873946 0.586 rs36084869 chr10:134566069 G/A cg17054783 chr10:134559939 INPP5A 0.24 4.83 0.4 3.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7786877 0.521 rs4729607 chr7:100326744 T/A cg20848291 chr7:100343083 ZAN -0.52 -4.45 -0.37 1.92e-5 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs832540 1.000 rs252914 chr5:56198150 A/C cg24531977 chr5:56204891 C5orf35 -0.52 -5.12 -0.42 1.12e-6 Coronary artery disease; TGCT cis rs2439831 1.000 rs2444250 chr15:43785051 C/G cg27015174 chr15:43622946 ADAL;LCMT2 0.79 5.51 0.44 1.95e-7 Lung cancer in ever smokers; TGCT cis rs3806843 0.576 rs246059 chr5:140325010 G/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs208346 0.612 rs208356 chr7:2775825 A/T cg11411865 chr7:2701802 TTYH3 -0.22 -5.08 -0.42 1.34e-6 Loneliness (linear analysis); TGCT trans rs608114 0.793 rs688184 chr6:96378265 G/A cg04008557 chr11:2826328 KCNQ1 -0.65 -6.82 -0.52 3.51e-10 Response to abacavir-containing treatment in HIV-1 infection (virologic failure);Response to efavirenz-containing treatment in HIV 1 infection (virologic failure); TGCT cis rs9341808 0.718 rs9448899 chr6:80845864 G/A cg08355045 chr6:80787529 NA 0.32 5.83 0.46 4.48e-8 Sitting height ratio; TGCT cis rs9291683 0.530 rs35908990 chr4:9976105 G/A cg11266682 chr4:10021025 SLC2A9 0.62 8.63 0.61 2.51e-14 Bone mineral density; TGCT cis rs9913156 0.553 rs1045280 chr17:4622638 C/T cg00122941 chr17:4613640 ARRB2 -0.78 -7.04 -0.53 1.14e-10 Lymphocyte counts; TGCT cis rs4783244 0.864 rs8062260 chr16:82658090 G/A cg09415485 chr16:82663111 CDH13 -0.25 -4.67 -0.39 7.77e-6 Adiponectin levels; TGCT cis rs12701220 0.857 rs1057558 chr7:1062366 A/G cg07217954 chr7:1067459 C7orf50 -0.45 -4.53 -0.38 1.39e-5 Bronchopulmonary dysplasia; TGCT cis rs2549003 0.933 rs7719499 chr5:131814091 C/G cg02551604 chr5:131831745 NA -0.89 -11.11 -0.71 2.52e-20 Asthma (sex interaction); TGCT cis rs78487399 0.808 rs74821293 chr2:43742923 T/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.73 4.78 0.39 4.97e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6460942 1.000 rs2033871 chr7:12405098 C/A cg06484146 chr7:12443880 VWDE -0.63 -5.65 -0.45 1.04e-7 Coronary artery disease; TGCT cis rs896854 0.967 rs896853 chr8:95960855 G/C cg09323728 chr8:95962352 TP53INP1 -0.55 -7.16 -0.54 6.26e-11 Type 2 diabetes; TGCT cis rs9309473 0.687 rs10165862 chr2:73610743 C/T cg20560298 chr2:73613845 ALMS1 -0.42 -4.58 -0.38 1.11e-5 Metabolite levels; TGCT cis rs12477438 0.765 rs10181422 chr2:99558970 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.75 -7.29 -0.55 3.21e-11 Chronic sinus infection; TGCT cis rs911263 0.961 rs7148416 chr14:68747868 A/T cg18825221 chr14:68749962 RAD51L1 0.27 5.44 0.44 2.71e-7 Primary biliary cholangitis; TGCT cis rs1215050 0.740 rs783932 chr4:98973936 C/G cg05340658 chr4:99064831 C4orf37 -0.43 -5.27 -0.43 5.8e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2982552 0.838 rs977533 chr6:152068874 G/A cg22157087 chr6:152012887 ESR1 0.2 4.77 0.39 5e-6 Bone properties (heel); TGCT cis rs9372498 0.536 rs62421539 chr6:118730559 C/A cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs9902453 0.967 rs6505155 chr17:28372783 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs4665809 0.878 rs6720312 chr2:26364934 A/G cg25036284 chr2:26402008 FAM59B 0.55 4.68 0.39 7.51e-6 Gut microbiome composition (summer); TGCT cis rs6674176 0.628 rs2240447 chr1:44415415 C/T cg13606994 chr1:44402422 ARTN -0.46 -4.98 -0.41 2.12e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs950027 0.620 rs2453533 chr15:45641225 C/A cg14582100 chr15:45693742 SPATA5L1 0.47 6.05 0.48 1.59e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs9381040 0.655 rs2268190 chr6:41030226 C/T cg03526776 chr6:41159608 TREML2 0.27 5.27 0.43 5.78e-7 Alzheimer's disease (late onset); TGCT cis rs7726839 0.526 rs55647623 chr5:567747 T/C cg09021430 chr5:549028 NA -0.42 -5.68 -0.45 9.25e-8 Obesity-related traits; TGCT cis rs8179 0.645 rs10264916 chr7:92286376 A/G cg15732164 chr7:92237376 CDK6 -0.28 -4.84 -0.4 3.78e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs9653442 0.900 rs10194635 chr2:100834217 T/A cg07810366 chr2:100720526 AFF3 -0.4 -6.06 -0.48 1.49e-8 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs909341 0.818 rs2259858 chr20:62346459 A/T cg14758556 chr20:62440591 NA 0.3 4.49 0.37 1.6e-5 Atopic dermatitis; TGCT cis rs6582630 0.519 rs11495700 chr12:38288240 A/G cg13010199 chr12:38710504 ALG10B 0.61 4.77 0.39 5.11e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs7223966 0.921 rs2727300 chr17:61965398 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.6 4.65 0.39 8.42e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs4077515 0.967 rs4266763 chr9:139289825 C/T cg13741927 chr9:139327495 INPP5E 0.21 5.0 0.41 1.87e-6 Ulcerative colitis;IgA nephropathy;Inflammatory bowel disease;Crohn's disease; TGCT cis rs1949733 1.000 rs1949733 chr4:8503359 C/T cg13073564 chr4:8508604 NA 0.48 5.2 0.42 8.02e-7 Response to antineoplastic agents; TGCT cis rs5769765 0.671 rs138817 chr22:50163058 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.0 -9.33 -0.64 5.41e-16 Schizophrenia; TGCT cis rs700651 0.789 rs116165148 chr2:198888347 T/G cg00792783 chr2:198669748 PLCL1 0.59 5.34 0.43 4.33e-7 Intracranial aneurysm; TGCT cis rs4665809 0.556 rs1560869 chr2:26417095 T/C cg22920501 chr2:26401640 FAM59B -0.79 -6.31 -0.49 4.58e-9 Gut microbiome composition (summer); TGCT cis rs9303401 0.614 rs12950028 chr17:56510140 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.68 6.69 0.52 6.76e-10 Cognitive test performance; TGCT cis rs1670533 0.585 rs6827206 chr4:1065071 A/T cg27284194 chr4:1044797 NA 0.69 5.94 0.47 2.66e-8 Recombination rate (females); TGCT cis rs3617 0.599 rs12487379 chr3:52895785 G/A cg11645453 chr3:52864694 ITIH4 0.25 4.82 0.4 4.08e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7044106 0.791 rs747819 chr9:123488441 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 5.44 0.44 2.74e-7 Hip circumference adjusted for BMI; TGCT cis rs1395 0.922 rs13404446 chr2:27519254 C/T cg14242246 chr2:27434262 C2orf28;SLC5A6 0.44 5.84 0.46 4.25e-8 Blood metabolite levels; TGCT cis rs9549260 0.609 rs9315780 chr13:41263960 C/T cg21288729 chr13:41239152 FOXO1 0.9 8.44 0.6 7.07e-14 Red blood cell count; TGCT cis rs7937682 0.632 rs10891297 chr11:111770150 C/T cg09085632 chr11:111637200 PPP2R1B 0.83 7.15 0.54 6.45e-11 Primary sclerosing cholangitis; TGCT cis rs4975709 1.000 rs2279588 chr5:1878021 G/A cg14773178 chr5:1868261 NA 0.37 4.71 0.39 6.42e-6 Cardiovascular disease risk factors; TGCT cis rs7666738 0.830 rs4699593 chr4:98980628 A/G cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.532 rs202627 chr22:41847367 A/T cg06634786 chr22:41940651 POLR3H 0.87 8.08 0.59 4.79e-13 Vitiligo; TGCT cis rs2710642 0.779 rs360807 chr2:62926859 C/T cg17519650 chr2:63277830 OTX1 -0.56 -4.85 -0.4 3.62e-6 LDL cholesterol levels;LDL cholesterol; TGCT cis rs12950390 0.853 rs12450729 chr17:45855363 A/G cg06532163 chr17:45867833 NA 0.37 5.86 0.47 3.9e-8 IgG glycosylation; TGCT cis rs6547741 1.000 rs13026621 chr2:27807624 G/A cg27432699 chr2:27873401 GPN1 0.18 4.65 0.38 8.53e-6 Oral cavity cancer; TGCT cis rs587847 0.522 rs582122 chr15:37687805 A/T cg16890051 chr15:37175029 LOC145845 -0.39 -4.65 -0.39 8.44e-6 Intraocular pressure; TGCT cis rs9611565 0.506 rs7364221 chr22:41650190 C/A cg03806693 chr22:41940476 POLR3H -0.76 -7.13 -0.54 7.2e-11 Vitiligo; TGCT cis rs909002 0.789 rs2139539 chr1:32117779 C/T cg11573219 chr1:32083031 HCRTR1 -0.38 -4.89 -0.4 3.03e-6 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs60651159 chr8:58174074 T/C cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs1552244 0.554 rs6786636 chr3:10045703 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs1372520 0.873 rs2583990 chr4:90771499 A/G cg20003494 chr4:90757398 SNCA -0.63 -5.13 -0.42 1.08e-6 Neuroticism; TGCT cis rs6459788 0.720 rs6965466 chr7:157250749 G/T cg03453431 chr7:157225567 NA -0.37 -5.68 -0.45 9.12e-8 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs74417235 0.684 rs7723610 chr5:154053349 A/C cg08754654 chr5:154026448 NA 0.58 5.53 0.44 1.84e-7 Reticulocyte count;Reticulocyte fraction of red cells;Mean corpuscular hemoglobin concentration; TGCT cis rs250677 1.000 rs36069 chr5:148417253 G/C cg18129178 chr5:148520854 ABLIM3 -0.43 -6.56 -0.51 1.31e-9 Breast cancer; TGCT cis rs7666738 0.861 rs13139309 chr4:99020916 A/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10114408 0.959 rs10821254 chr9:96655855 A/G cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 7e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs9467711 0.651 rs2237228 chr6:26104630 C/T cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.57 -4.54 -0.38 1.33e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9682041 1.000 rs6773095 chr3:170082181 A/G cg07589077 chr3:170072950 NA 0.31 4.7 0.39 6.94e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs13082711 0.516 rs13084067 chr3:27358935 A/T cg02860705 chr3:27208620 NA 0.44 6.92 0.53 2.15e-10 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs12188164 0.686 rs11741946 chr5:421403 G/A cg26850624 chr5:429559 AHRR -0.21 -4.93 -0.4 2.61e-6 Cystic fibrosis severity; TGCT cis rs13326165 0.760 rs67248391 chr3:52412006 A/T cg27565382 chr3:53032988 SFMBT1 0.37 4.9 0.4 2.97e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs9486719 1.000 rs6923212 chr6:97061940 A/G cg18709589 chr6:96969512 KIAA0776 -0.73 -5.5 -0.44 2.04e-7 Migraine;Coronary artery disease; TGCT cis rs806215 1.000 rs327512 chr7:127257251 G/A cg25922125 chr7:127225783 GCC1 0.47 4.79 0.4 4.62e-6 Type 2 diabetes; TGCT cis rs875971 0.862 rs7809814 chr7:65615397 G/A cg11764359 chr7:65958608 NA -0.56 -5.09 -0.42 1.31e-6 Aortic root size; TGCT cis rs1801251 0.778 rs809639 chr2:233731244 C/G cg25237894 chr2:233734115 C2orf82 0.3 5.84 0.46 4.33e-8 Coronary artery disease; TGCT cis rs13191362 1.000 rs4489133 chr6:163137793 C/T cg21926612 chr6:163149169 PACRG;PARK2 1.17 9.35 0.64 4.74e-16 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6964587 1.000 rs12540565 chr7:91633213 T/G cg22709100 chr7:91322751 NA 0.27 4.48 0.37 1.68e-5 Breast cancer; TGCT cis rs7809950 0.817 rs2712230 chr7:107294151 G/A cg23024343 chr7:107201750 COG5 0.41 5.78 0.46 5.71e-8 Coronary artery disease; TGCT cis rs10504229 0.679 rs16921676 chr8:58052386 G/T cg11062466 chr8:58055876 NA 0.34 4.67 0.39 7.73e-6 Developmental language disorder (linguistic errors); TGCT cis rs2439831 0.681 rs498837 chr15:43608024 G/A cg02155558 chr15:43621948 ADAL;LCMT2 1.02 8.51 0.61 4.91e-14 Lung cancer in ever smokers; TGCT cis rs11574514 1.000 rs75760574 chr16:67644173 G/A cg00545966 chr16:67701244 C16orf86;C16orf48 0.72 4.45 0.37 1.87e-5 Crohn's disease; TGCT cis rs3858526 0.514 rs4595572 chr11:5864045 T/G cg13902645 chr11:5959945 NA -0.39 -4.57 -0.38 1.16e-5 DNA methylation (variation); TGCT cis rs80282103 0.867 rs80254477 chr10:1077387 T/G cg18964960 chr10:1102726 WDR37 1.09 4.69 0.39 7.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs9650657 0.530 rs6982381 chr8:10952500 A/T cg27411982 chr8:10470053 RP1L1 -0.21 -4.59 -0.38 1.08e-5 Neuroticism; TGCT cis rs17376456 0.569 rs10057664 chr5:93182274 C/T cg21475434 chr5:93447410 FAM172A -0.68 -5.22 -0.42 7.16e-7 Diabetic retinopathy; TGCT cis rs9611565 0.765 rs9607800 chr22:41784562 A/G cg13695892 chr22:41940480 POLR3H -0.78 -7.66 -0.57 4.58e-12 Vitiligo; TGCT cis rs28386778 0.897 rs4968597 chr17:61805747 G/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs67311347 1.000 rs73076046 chr3:40447724 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs1451375 0.669 rs4469404 chr7:50647062 C/T cg18232548 chr7:50535776 DDC -0.46 -7.1 -0.54 8.31e-11 Malaria; TGCT cis rs9906944 0.545 rs11079851 chr17:47092310 G/C cg20966754 chr17:47091339 IGF2BP1 -0.41 -4.48 -0.37 1.65e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs704 1.000 rs704 chr17:26694861 G/A cg10342447 chr17:26645325 TMEM97 -0.49 -4.64 -0.38 8.82e-6 Osteoprotegerin levels; TGCT cis rs7267979 0.868 rs6138550 chr20:25223430 C/T cg03522245 chr20:25566470 NINL 0.6 6.58 0.51 1.21e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9467773 0.935 rs1884947 chr6:26553273 G/T cg26531700 chr6:26746687 NA 0.67 7.07 0.54 1.02e-10 Intelligence (multi-trait analysis); TGCT cis rs2841277 0.708 rs10083496 chr14:105402786 G/A cg19901468 chr14:105411992 AHNAK2 -0.28 -5.93 -0.47 2.77e-8 Rheumatoid arthritis; TGCT cis rs7647973 0.516 rs4536858 chr3:49193081 A/G cg03060546 chr3:49711283 APEH 0.51 4.82 0.4 4.2e-6 Menarche (age at onset); TGCT cis rs34526934 0.566 rs9141 chr2:177037970 T/C cg14324370 chr2:177042789 NA -0.91 -8.67 -0.61 2.03e-14 Obstructive sleep apnea trait (apnea hypopnea index); TGCT cis rs986417 1.000 rs2351176 chr14:61073731 A/T cg27398547 chr14:60952738 C14orf39 1.41 8.43 0.6 7.41e-14 Gut microbiota (bacterial taxa); TGCT cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg11644478 chr21:40555479 PSMG1 1.04 10.72 0.69 2.25e-19 Cognitive function; TGCT cis rs1218582 0.804 rs4845398 chr1:154859038 G/C cg03351412 chr1:154909251 PMVK 0.52 4.8 0.4 4.51e-6 Prostate cancer; TGCT cis rs7267979 1.000 rs1047171 chr20:25428786 T/C cg03522245 chr20:25566470 NINL 0.63 6.8 0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1580019 0.587 rs6968990 chr7:32552159 C/T cg07520158 chr7:32535189 LSM5;AVL9 -0.57 -4.73 -0.39 6.04e-6 Cognitive ability; TGCT cis rs10992471 0.603 rs755209 chr9:95489671 G/A cg13798575 chr9:95087839 CENPP;NOL8 -0.53 -4.58 -0.38 1.13e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT trans rs17685 0.753 rs1637037 chr7:75692927 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 8.93 0.63 4.87e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs6582630 0.555 rs2004152 chr12:38478951 C/T cg26384229 chr12:38710491 ALG10B 0.88 8.04 0.59 5.98e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs2235642 0.859 rs12599207 chr16:1606445 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.3 -5.32 -0.43 4.74e-7 Coronary artery disease; TGCT cis rs9611519 0.754 rs4820435 chr22:41652846 G/T cg03806693 chr22:41940476 POLR3H -0.77 -7.59 -0.56 6.65e-12 Neuroticism; TGCT cis rs514406 0.698 rs11206043 chr1:53402552 C/T cg25767906 chr1:53392781 SCP2 -0.59 -7.45 -0.56 1.37e-11 Monocyte count; TGCT cis rs919433 0.647 rs6741205 chr2:198525997 G/C cg00792783 chr2:198669748 PLCL1 0.55 4.88 0.4 3.24e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs854765 0.565 rs854768 chr17:18018806 T/C cg24612305 chr17:17875800 TOM1L2;LRRC48 0.71 7.37 0.55 2.15e-11 Total body bone mineral density; TGCT cis rs6598955 0.640 rs6667826 chr1:26531408 T/C cg01614726 chr1:26633154 UBXN11 0.5 4.67 0.39 7.56e-6 Obesity-related traits; TGCT cis rs854765 0.583 rs7214002 chr17:17852104 G/C cg09796270 chr17:17721594 SREBF1 0.23 4.56 0.38 1.22e-5 Total body bone mineral density; TGCT cis rs67311347 1.000 rs7617989 chr3:40512463 A/G cg13683864 chr3:40499215 RPL14 1.04 10.6 0.69 4.48e-19 Renal cell carcinoma; TGCT cis rs2204008 0.683 rs7305703 chr12:38138381 T/C cg26384229 chr12:38710491 ALG10B 0.85 7.68 0.57 4.21e-12 Bladder cancer; TGCT cis rs12519773 0.549 rs11738974 chr5:92537336 G/A cg04854328 chr5:92914828 FLJ42709 -0.3 -4.55 -0.38 1.24e-5 Migraine; TGCT cis rs4689388 0.824 rs4467645 chr4:6294305 C/T cg25554036 chr4:6271136 WFS1 0.54 7.37 0.55 2.11e-11 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4953076 0.573 rs6726680 chr2:44406686 C/G cg00619915 chr2:44497795 NA -0.22 -4.9 -0.4 2.88e-6 Height; TGCT cis rs2594989 1.000 rs2606761 chr3:11344427 G/A cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs2216164 0.901 rs10878756 chr12:68522610 T/C cg17065850 chr12:67807625 NA 0.25 4.57 0.38 1.15e-5 Alopecia areata; TGCT cis rs9467773 0.596 rs2494693 chr6:26619226 T/C cg02458000 chr6:26745757 NA 0.55 5.25 0.43 6.28e-7 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs55787104 chr8:58178519 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.22 -0.42 7.36e-7 Developmental language disorder (linguistic errors); TGCT cis rs6840360 0.615 rs7695412 chr4:152488075 A/G cg17479576 chr4:152424074 FAM160A1 -0.72 -7.98 -0.58 8.25e-13 Intelligence (multi-trait analysis); TGCT cis rs9534288 0.659 rs2146882 chr13:46668111 A/G cg15192986 chr13:46630673 CPB2 -0.51 -6.12 -0.48 1.16e-8 Blood protein levels; TGCT cis rs6951245 0.638 rs74976697 chr7:1160505 C/T cg23708337 chr7:1209742 NA 0.56 5.43 0.44 2.83e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7201929 1.000 rs12920514 chr16:28835900 G/A cg09754948 chr16:28834200 ATXN2L -0.61 -4.55 -0.38 1.27e-5 QT interval; TGCT cis rs11167764 1.000 rs13354528 chr5:141476769 C/T cg23435118 chr5:141488016 NDFIP1 -0.27 -4.48 -0.37 1.65e-5 Crohn's disease; TGCT cis rs62283056 0.512 rs1079215 chr4:6282393 A/G cg25554036 chr4:6271136 WFS1 0.53 6.84 0.52 3.27e-10 Cisplatin-induced ototoxicity; TGCT cis rs34091558 1 rs34091558 chr1:201886769 TA/T cg12730843 chr1:201915899 LMOD1 -0.27 -4.59 -0.38 1.07e-5 Breast size; TGCT cis rs2739330 0.789 rs5760109 chr22:24252938 C/G cg02953382 chr22:24373134 LOC391322 -0.77 -8.01 -0.58 7.12e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2797160 1.000 rs926853 chr6:126021435 A/T cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 4.92e-9 Endometrial cancer; TGCT cis rs6684514 1.000 rs6800 chr1:156262653 A/C cg16558208 chr1:156270281 VHLL 0.46 9.38 0.64 3.92e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs61897795 0.657 rs174590 chr11:61616977 G/C cg19610905 chr11:61596333 FADS2 -0.62 -4.73 -0.39 5.88e-6 Neutrophil count;Sum basophil neutrophil counts; TGCT cis rs68170813 0.523 rs12535093 chr7:107020182 C/T cg02696742 chr7:106810147 HBP1 -0.73 -5.95 -0.47 2.6e-8 Coronary artery disease; TGCT cis rs72717009 0.825 rs12746613 chr1:161467042 A/G cg23840854 chr1:161414152 NA 1.01 6.21 0.49 7.46e-9 Rheumatoid arthritis; TGCT cis rs736408 0.609 rs13087772 chr3:52782274 T/G cg10802521 chr3:52805072 NEK4 -0.73 -9.23 -0.64 9.18e-16 Bipolar disorder; TGCT cis rs877282 0.945 rs11253398 chr10:790012 T/C cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs13108904 0.967 rs12502916 chr4:1276349 G/A cg00684032 chr4:1343700 KIAA1530 -0.23 -4.98 -0.41 2.08e-6 Obesity-related traits; TGCT cis rs950169 0.922 rs12911223 chr15:84831671 G/A cg11189052 chr15:85197271 WDR73 -0.81 -6.5 -0.5 1.78e-9 Schizophrenia; TGCT cis rs9611565 0.918 rs9611566 chr22:41768625 A/G cg03806693 chr22:41940476 POLR3H 1.13 13.66 0.78 1.74e-26 Vitiligo; TGCT trans rs57221529 0.766 rs4081846 chr5:574019 G/A cg11887960 chr12:57824829 NA 1.1 9.51 0.65 1.98e-16 Lung disease severity in cystic fibrosis; TGCT cis rs10782582 0.609 rs1796827 chr1:76391536 A/T cg03433033 chr1:76189801 ACADM -0.47 -4.65 -0.39 8.23e-6 Daytime sleep phenotypes; TGCT cis rs7513165 0.867 rs4951318 chr1:204161513 G/C cg04791601 chr1:204159016 NA 0.26 5.21 0.42 7.68e-7 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg18230493 chr5:56204884 C5orf35 -0.68 -5.92 -0.47 2.92e-8 Initial pursuit acceleration; TGCT cis rs3087591 0.853 rs2953003 chr17:29502731 T/C cg24425628 chr17:29625626 OMG;NF1 0.45 6.95 0.53 1.84e-10 Hip circumference; TGCT cis rs651907 0.535 rs35799195 chr3:101521927 A/G cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs5760092 0.618 rs5996631 chr22:24256894 T/C cg04234412 chr22:24373322 LOC391322 0.92 8.49 0.61 5.45e-14 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs1552244 0.744 rs6763366 chr3:10033544 T/C cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs896854 0.654 rs13274945 chr8:95986626 C/T cg16049864 chr8:95962084 TP53INP1 -0.72 -10.2 -0.68 4.16e-18 Type 2 diabetes; TGCT cis rs3785574 0.650 rs2070776 chr17:62007498 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.55 -4.85 -0.4 3.63e-6 Height; TGCT trans rs9383153 1.000 rs2073518 chr6:16332730 T/C cg19776793 chr17:79225974 SLC38A10 0.81 6.76 0.52 4.83e-10 Gambling; TGCT cis rs9911578 1.000 rs1971659 chr17:57004787 A/G cg12560992 chr17:57184187 TRIM37 0.76 9.21 0.64 1.03e-15 Intelligence (multi-trait analysis); TGCT cis rs12497850 1.000 rs10865952 chr3:48744484 A/G cg06212747 chr3:49208901 KLHDC8B 0.62 5.94 0.47 2.65e-8 Parkinson's disease; TGCT cis rs3540 0.960 rs6496675 chr15:90982756 C/T cg22089800 chr15:90895588 ZNF774 0.72 6.59 0.51 1.15e-9 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs10465746 0.967 rs1570690 chr1:84377515 G/T cg10977910 chr1:84465055 TTLL7 0.63 6.19 0.49 8.08e-9 Obesity-related traits; TGCT cis rs7945705 0.747 rs11042150 chr11:9010819 T/C cg21881798 chr11:8931708 C11orf17;ST5 -0.45 -4.82 -0.4 4.11e-6 Hemoglobin concentration; TGCT cis rs826838 0.935 rs1843639 chr12:39178919 C/A cg13010199 chr12:38710504 ALG10B 0.78 6.16 0.48 9.26e-9 Heart rate; TGCT cis rs6430585 0.528 rs309123 chr2:136761175 C/G cg07169764 chr2:136633963 MCM6 1.2 11.53 0.72 2.34e-21 Corneal structure; TGCT cis rs3806843 1.000 rs6579987 chr5:140183659 T/C cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7917772 0.636 rs7088981 chr10:104520423 T/C cg11453585 chr10:104263688 ACTR1A;SUFU -0.57 -4.62 -0.38 9.3e-6 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9584850 0.834 rs7339274 chr13:99120272 A/G cg15168958 chr13:99100528 FARP1 0.25 4.84 0.4 3.76e-6 Neuroticism; TGCT cis rs7618915 0.547 rs6976 chr3:52728804 C/T cg07507251 chr3:52567010 NT5DC2 0.49 7.11 0.54 8.16e-11 Bipolar disorder; TGCT cis rs13064411 0.735 rs7631138 chr3:113231925 A/T cg18753928 chr3:113234510 CCDC52 -0.7 -5.68 -0.45 9.16e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs4819052 1.000 rs13053002 chr21:46677854 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.75 5.55 0.45 1.67e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs734999 0.588 rs11585048 chr1:2534087 C/T cg18854424 chr1:2615690 NA 0.44 5.1 0.42 1.22e-6 Ulcerative colitis; TGCT cis rs514406 0.505 rs448788 chr1:53161620 A/G cg16325326 chr1:53192061 ZYG11B -0.86 -11.53 -0.72 2.4e-21 Monocyte count; TGCT cis rs6740322 1.000 rs11693666 chr2:43562479 A/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.38 6.32 0.49 4.21e-9 Coronary artery disease; TGCT cis rs7044106 0.762 rs1411158 chr9:123464804 A/G cg09419670 chr9:123605666 PSMD5;LOC253039 0.61 6.47 0.5 2.01e-9 Hip circumference adjusted for BMI; TGCT cis rs7772486 0.594 rs6901864 chr6:146023050 C/A cg23711669 chr6:146136114 FBXO30 -0.96 -11.06 -0.7 3.28e-20 Lobe attachment (rater-scored or self-reported); TGCT cis rs1371867 0.875 rs28595052 chr8:101327553 G/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs9388451 0.807 rs1268065 chr6:126042783 G/A cg10911889 chr6:126070802 HEY2 -0.52 -5.26 -0.43 6.17e-7 Brugada syndrome; TGCT cis rs1008375 1.000 rs2058339 chr4:17678456 C/T cg18681998 chr4:17616180 MED28 0.89 10.34 0.68 1.84e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12103 0.749 rs2649599 chr1:1305493 A/G cg14089984 chr1:1182418 FAM132A 0.37 4.77 0.39 5.06e-6 Ulcerative colitis;Inflammatory bowel disease;Crohn's disease; TGCT cis rs908922 0.651 rs1572534 chr1:152509689 G/A cg20991723 chr1:152506922 NA 0.46 6.18 0.48 8.66e-9 Hair morphology; TGCT cis rs2072499 0.865 rs2758608 chr1:156202860 A/T cg06970220 chr1:156163860 SLC25A44 0.71 5.87 0.47 3.81e-8 Testicular germ cell tumor; TGCT cis rs637571 0.522 rs1151512 chr11:65757533 G/A cg02427764 chr11:65769310 BANF1;EIF1AD 0.67 6.69 0.51 6.89e-10 Eosinophil percentage of white cells; TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg22166914 chr1:53195759 ZYG11B 0.3 4.87 0.4 3.29e-6 Monocyte count; TGCT cis rs78456975 0.506 rs13384333 chr2:1555531 A/C cg01028140 chr2:1542097 TPO -0.32 -4.86 -0.4 3.54e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs11190604 1.000 rs10883496 chr10:102221931 T/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9811920 0.742 rs2316263 chr3:99900096 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 -0.4 -4.68 -0.39 7.28e-6 Axial length; TGCT cis rs838147 0.537 rs504963 chr19:49208865 G/A cg05248581 chr19:49925731 PTH2 0.42 4.55 0.38 1.28e-5 Dietary macronutrient intake; TGCT cis rs9611565 0.840 rs9607799 chr22:41777558 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.26 -0.43 6.14e-7 Vitiligo; TGCT cis rs10751667 0.857 rs6597952 chr11:991109 C/G cg06064525 chr11:970664 AP2A2 -0.3 -6.06 -0.48 1.51e-8 Alzheimer's disease (late onset); TGCT cis rs2013441 0.786 rs4003797 chr17:20288900 T/C cg18979559 chr17:20280153 CCDC144C -0.44 -4.56 -0.38 1.21e-5 Obesity-related traits; TGCT cis rs11190604 1.000 rs2298074 chr10:102247526 G/C cg16342193 chr10:102329863 NA -0.41 -5.34 -0.43 4.25e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2439831 0.867 rs2447208 chr15:43933895 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.73 4.95 0.41 2.38e-6 Lung cancer in ever smokers; TGCT cis rs4803468 1.000 rs4803465 chr19:41918158 A/G cg09537434 chr19:41945824 ATP5SL 0.91 10.85 0.7 1.06e-19 Height; TGCT cis rs6964587 0.967 rs6974827 chr7:91772945 C/T cg22709100 chr7:91322751 NA 0.29 4.62 0.38 9.33e-6 Breast cancer; TGCT cis rs769267 0.965 rs4808938 chr19:19401218 G/A cg02546618 chr19:19431379 KIAA0892;SF4 0.61 5.06 0.41 1.5e-6 Tonsillectomy; TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs7267979 1.000 rs6050544 chr20:25320228 T/A cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3091242 0.728 rs706845 chr1:25730713 G/A cg10117171 chr1:25599238 RHD -0.36 -5.73 -0.46 7.35e-8 Erythrocyte sedimentation rate; TGCT cis rs7493 0.901 rs17883318 chr7:94958312 G/A cg17330251 chr7:94953956 PON1 -0.45 -4.45 -0.37 1.93e-5 Yu-Zhi constitution type in type 2 diabetes; TGCT cis rs7914558 0.901 rs35525740 chr10:104941112 A/T cg15744005 chr10:104629667 AS3MT -0.39 -4.75 -0.39 5.53e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs11190604 1.000 rs74210981 chr10:102287520 C/T cg16342193 chr10:102329863 NA -0.44 -5.56 -0.45 1.58e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs5769765 0.955 rs5769761 chr22:50263641 G/T cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs17401966 0.898 rs11582123 chr1:10303942 A/T cg19773385 chr1:10388646 KIF1B -0.21 -4.6 -0.38 1.02e-5 Hepatocellular carcinoma; TGCT cis rs873946 0.504 rs12254034 chr10:134571007 T/C cg26818010 chr10:134567672 INPP5A -0.39 -5.51 -0.44 1.96e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4925386 0.559 rs2427291 chr20:60921324 G/A cg06026331 chr20:60912101 LAMA5 0.35 5.44 0.44 2.74e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs709400 0.658 rs72708874 chr14:103899251 T/G cg26031613 chr14:104095156 KLC1 0.85 9.31 0.64 6e-16 Body mass index; TGCT cis rs11190604 0.943 rs11190588 chr10:102273565 C/T cg23241863 chr10:102295624 HIF1AN 0.67 4.89 0.4 3.03e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9926296 0.744 rs154656 chr16:89708003 T/A cg27121462 chr16:89883253 FANCA -0.49 -4.54 -0.38 1.31e-5 Vitiligo; TGCT cis rs2463822 0.858 rs2513077 chr11:62105925 A/G cg23876832 chr11:62092739 NA -0.67 -5.0 -0.41 1.95e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT trans rs1005277 0.579 rs9418322 chr10:38377296 G/T cg17830980 chr10:43048298 ZNF37B -0.87 -11.11 -0.71 2.53e-20 Extrinsic epigenetic age acceleration; TGCT cis rs3812831 0.669 rs382913 chr13:114928255 G/T cg15513719 chr13:114904418 NA 0.38 4.64 0.38 8.57e-6 Schizophrenia; TGCT cis rs12134245 0.776 rs12137878 chr1:91973210 G/T cg02896835 chr1:92012615 NA -0.29 -4.77 -0.39 4.98e-6 Breast cancer; TGCT cis rs12530845 1.000 rs73721606 chr7:135335678 C/T cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs6964587 0.773 rs13223564 chr7:91932666 A/G cg17063962 chr7:91808500 NA 0.83 7.96 0.58 9.29e-13 Breast cancer; TGCT cis rs709400 0.930 rs10134399 chr14:104083457 G/A cg26031613 chr14:104095156 KLC1 1.15 16.05 0.82 4.72e-32 Body mass index; TGCT cis rs7586879 0.616 rs916485 chr2:25082273 T/C cg01884057 chr2:25150051 NA 0.33 6.25 0.49 6.16e-9 Body mass index; TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg05457628 chr5:178986728 RUFY1 0.44 4.63 0.38 9.2e-6 Lung cancer; TGCT cis rs17125944 0.686 rs73304351 chr14:53375140 G/A cg00686598 chr14:53173677 PSMC6 0.89 4.44 0.37 1.99e-5 Alzheimer's disease (late onset); TGCT cis rs763121 0.853 rs2267394 chr22:39101633 T/C cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT cis rs55665837 0.778 rs11023212 chr11:14431709 G/A cg19336497 chr11:14380999 RRAS2 -0.29 -4.5 -0.37 1.53e-5 Vitamin D levels; TGCT cis rs875971 1.000 rs875971 chr7:65617595 A/G cg18876405 chr7:65276391 NA -0.33 -5.08 -0.42 1.33e-6 Aortic root size; TGCT cis rs2013441 1.000 rs8079701 chr17:20216565 G/A cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs4555082 1.000 rs4555082 chr14:105758964 C/T cg10792982 chr14:105748885 BRF1 0.22 4.48 0.37 1.7e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs6684514 1.000 rs12118238 chr1:156235221 G/A cg16558208 chr1:156270281 VHLL 0.47 9.2 0.64 1.1e-15 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs10256972 0.552 rs2960837 chr7:1203957 A/G cg17775962 chr7:1200435 ZFAND2A 0.28 4.76 0.39 5.27e-6 Longevity;Endometriosis; TGCT cis rs3733585 0.673 rs4447861 chr4:9953940 C/T cg11266682 chr4:10021025 SLC2A9 -0.57 -7.6 -0.56 6.21e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1215050 0.791 rs260893 chr4:98744785 A/C cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12048904 0.619 rs3737581 chr1:101341083 A/G cg16556008 chr1:101360663 SLC30A7;EXTL2 0.86 7.41 0.55 1.68e-11 Multiple sclerosis; TGCT trans rs11722228 0.549 rs73212828 chr4:10078756 C/T cg26043149 chr18:55253948 FECH 1.15 11.28 0.71 9.49e-21 Gout;Urate levels;Serum uric acid levels; TGCT cis rs11098499 1.000 rs6849889 chr4:120186348 A/C cg24670566 chr4:120433619 PDE5A 0.23 4.65 0.39 8.5e-6 Corneal astigmatism; TGCT cis rs7666738 0.830 rs34212748 chr4:99068708 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs875971 0.862 rs1643375 chr7:65872677 T/C cg11764359 chr7:65958608 NA 0.57 5.28 0.43 5.64e-7 Aortic root size; TGCT cis rs587847 0.567 rs28875580 chr15:37764569 C/T cg00216138 chr15:37171175 LOC145845 0.31 4.45 0.37 1.86e-5 Intraocular pressure; TGCT cis rs8017423 0.935 rs11621820 chr14:90727154 C/T cg04374321 chr14:90722782 PSMC1 0.78 7.87 0.58 1.52e-12 Mortality in heart failure; TGCT cis rs1008375 1.000 rs4642241 chr4:17617111 T/C cg10189774 chr4:17578691 LAP3 0.55 4.92 0.4 2.69e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7302981 1.000 rs7302981 chr12:50537815 A/G cg23855989 chr12:50355821 AQP5 -0.3 -4.5 -0.38 1.52e-5 Systolic blood pressure; TGCT cis rs2120019 0.608 rs4886414 chr15:75308650 C/T cg17294928 chr15:75287854 SCAMP5 0.94 9.05 0.63 2.49e-15 Blood trace element (Zn levels); TGCT cis rs7216064 0.734 rs11653507 chr17:65892064 A/T cg12091567 chr17:66097778 LOC651250 -0.62 -5.29 -0.43 5.46e-7 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs13102973 0.720 rs7668824 chr4:135884707 A/T cg14419869 chr4:135874104 NA 0.26 4.56 0.38 1.2e-5 Subjective well-being; TGCT cis rs2692947 0.655 rs4605406 chr2:96583735 A/C cg13655245 chr2:97463316 CNNM4 0.15 4.53 0.38 1.37e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs28735056 1.000 rs4798923 chr18:77629373 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.55 -0.45 1.65e-7 Schizophrenia; TGCT cis rs6952808 0.689 rs12668156 chr7:2019875 G/A cg22963979 chr7:1858916 MAD1L1 -0.42 -6.74 -0.52 5.22e-10 Bipolar disorder and schizophrenia; TGCT cis rs7100689 0.646 rs4265545 chr10:82119271 G/T cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs10479542 0.702 rs13183521 chr5:178975606 A/G cg00080972 chr5:178986291 RUFY1 -0.44 -5.25 -0.43 6.45e-7 Lung cancer; TGCT cis rs6665290 0.904 rs9727512 chr1:227185375 G/T cg10327440 chr1:227177885 CDC42BPA -0.98 -19.76 -0.87 4.01e-40 Myeloid white cell count; TGCT cis rs4819052 0.851 rs4819041 chr21:46659955 C/T cg06618935 chr21:46677482 NA -0.34 -5.26 -0.43 6.1e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs904251 0.828 rs2797803 chr6:37487340 T/C cg25019722 chr6:37503610 NA -0.51 -7.03 -0.53 1.24e-10 Cognitive performance; TGCT cis rs9486719 1.000 rs2205755 chr6:96864704 A/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs360798 0.512 rs9973612 chr2:63019815 G/C cg17519650 chr2:63277830 OTX1 -0.64 -5.62 -0.45 1.22e-7 Coronary artery disease; TGCT cis rs12900413 0.562 rs28450767 chr15:90298228 A/G cg24249390 chr15:90295951 MESP1 -0.29 -5.11 -0.42 1.19e-6 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs6570726 1.000 rs951143 chr6:145932576 C/T cg23711669 chr6:146136114 FBXO30 0.7 6.41 0.5 2.81e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs425277 0.606 rs2503705 chr1:2076741 A/G cg03732007 chr1:2071316 PRKCZ 0.28 6.35 0.5 3.74e-9 Height; TGCT cis rs1691799 0.867 rs1168309 chr12:66726439 A/G cg16791601 chr12:66731901 HELB 0.29 6.44 0.5 2.34e-9 White blood cell count (basophil); TGCT cis rs5750830 0.597 rs4821889 chr22:39777254 T/C cg24399712 chr22:39784796 NA -0.98 -12.63 -0.75 5.18e-24 Intelligence (multi-trait analysis); TGCT cis rs35146811 0.657 rs36019559 chr7:99814586 A/G cg00553149 chr7:99775558 STAG3;GPC2 -0.31 -4.61 -0.38 9.75e-6 Coronary artery disease; TGCT cis rs8056742 0.554 rs11647764 chr16:85079813 C/T cg00229868 chr16:85520891 NA -0.35 -4.86 -0.4 3.49e-6 Amyotrophic lateral sclerosis; TGCT cis rs508618 0.666 rs480902 chr1:231531627 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.58 5.17 0.42 9e-7 Red blood cell count; TGCT cis rs7267979 0.753 rs404148 chr20:25447931 A/G cg21995068 chr20:25989032 LOC100134868 -0.43 -5.18 -0.42 8.85e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs10193935 0.901 rs13384404 chr2:42601147 G/T cg27598129 chr2:42591480 NA -0.4 -5.44 -0.44 2.71e-7 Colonoscopy-negative controls vs population controls; TGCT trans rs9329221 0.617 rs615632 chr8:9796321 C/T cg06636001 chr8:8085503 FLJ10661 -0.77 -7.67 -0.57 4.36e-12 Neuroticism; TGCT cis rs7917772 0.503 rs7915589 chr10:104299264 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4566357 0.521 rs78411533 chr2:227910807 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -5.24 -0.43 6.55e-7 Coronary artery disease; TGCT cis rs7666738 0.924 rs11097592 chr4:98927532 C/T cg18180107 chr4:99064573 C4orf37 0.56 4.78 0.39 4.8e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8014204 0.781 rs10143492 chr14:75212114 G/C cg06637938 chr14:75390232 RPS6KL1 0.54 4.83 0.4 3.97e-6 Caffeine consumption; TGCT cis rs7904368 0.806 rs7900527 chr10:16857992 C/G cg14835575 chr10:16859367 RSU1 0.71 7.55 0.56 8.2e-12 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs1008375 1.000 rs1121089 chr4:17676476 C/A cg10189774 chr4:17578691 LAP3 0.53 5.0 0.41 1.91e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs826838 0.935 rs11169511 chr12:39175802 T/C cg13010199 chr12:38710504 ALG10B 0.78 6.16 0.48 9.26e-9 Heart rate; TGCT cis rs6770219 0.516 rs56368029 chr3:186140882 C/T cg20306810 chr3:186501757 SNORD2;EIF4A2 0.73 4.46 0.37 1.81e-5 Cerebrospinal T-tau levels; TGCT cis rs4654899 0.865 rs72973154 chr1:21459125 G/T cg01072550 chr1:21505969 NA -0.48 -7.21 -0.54 4.91e-11 Superior frontal gyrus grey matter volume; TGCT cis rs6951245 0.872 rs74360401 chr7:1067403 G/A cg03188948 chr7:1209495 NA 0.6 4.89 0.4 3.02e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9303401 0.659 rs36109237 chr17:56653834 A/G cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs17826219 0.706 rs73271850 chr17:29142140 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Body mass index; TGCT cis rs9818758 0.556 rs13086240 chr3:49001409 G/A cg00383909 chr3:49044727 WDR6 1.26 6.52 0.51 1.58e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs6912958 0.712 rs2754260 chr6:88397666 T/C cg06598631 chr6:88300029 RARS2;ORC3L -0.51 -4.84 -0.4 3.73e-6 Monocyte percentage of white cells; TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg22166914 chr1:53195759 ZYG11B 0.37 6.41 0.5 2.77e-9 Monocyte count; TGCT cis rs11264213 0.591 rs1967782 chr1:36543783 C/T cg27506609 chr1:36549197 TEKT2 -0.33 -4.88 -0.4 3.15e-6 Schizophrenia; TGCT cis rs758129 0.578 rs7497468 chr15:89883147 G/T cg24365117 chr15:89879190 POLG -0.35 -4.89 -0.4 3.1e-6 Schizophrenia; TGCT cis rs7582180 0.591 rs2241810 chr2:101011877 T/C cg14675211 chr2:100938903 LONRF2 0.5 4.77 0.39 5.18e-6 Intelligence (multi-trait analysis); TGCT cis rs66573146 0.831 rs67602077 chr4:7024244 A/G cg05069807 chr4:6945702 TBC1D14 0.36 5.11 0.42 1.2e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7611238 0.560 rs4677669 chr3:195051300 C/T cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.94e-6 Body mass index; TGCT cis rs116095464 0.558 rs62347678 chr5:227496 A/G cg12570787 chr5:219185 SDHA;CCDC127 0.66 4.49 0.37 1.62e-5 Breast cancer; TGCT cis rs10504229 0.953 rs66676208 chr8:58173866 C/T cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs362272 0.545 rs2749785 chr4:3325179 G/C cg22655196 chr4:3374909 RGS12 0.23 4.55 0.38 1.24e-5 Serum sulfate level; TGCT cis rs2739330 0.760 rs1007888 chr22:24241101 C/T cg23131131 chr22:24373011 LOC391322 -0.7 -7.17 -0.54 6.03e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9486719 0.843 rs2499792 chr6:96846264 A/C cg18709589 chr6:96969512 KIAA0776 0.75 5.13 0.42 1.1e-6 Migraine;Coronary artery disease; TGCT cis rs17711722 0.503 rs453835 chr7:65511159 T/A cg05627663 chr7:65219948 SNORA22;CCT6P1 -0.24 -4.53 -0.38 1.37e-5 Calcium levels; TGCT cis rs6964587 1.000 rs13231820 chr7:91663529 A/G cg22709100 chr7:91322751 NA 0.27 4.46 0.37 1.84e-5 Breast cancer; TGCT cis rs2928148 0.522 rs11858278 chr15:41416276 T/C cg18705301 chr15:41695430 NDUFAF1 -0.61 -7.87 -0.58 1.52e-12 Glomerular filtration rate in non diabetics (creatinine); TGCT cis rs951366 0.764 rs823143 chr1:205743425 A/C cg24503407 chr1:205819492 PM20D1 0.6 8.5 0.61 5e-14 Menarche (age at onset); TGCT cis rs12510870 0.634 rs56011127 chr4:74386212 C/T cg05868023 chr4:75230803 EREG -0.55 -4.7 -0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs9467711 0.659 rs35680819 chr6:26455814 T/C cg16898833 chr6:26189333 HIST1H4D 1.26 5.95 0.47 2.59e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs67311347 1.000 rs4973878 chr3:40407565 C/T cg17264618 chr3:40429014 ENTPD3 0.32 4.76 0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs6921919 0.583 rs34513104 chr6:28343343 G/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2180341 1.000 rs2057223 chr6:127637374 T/C cg27446573 chr6:127587934 RNF146 1.12 10.11 0.67 6.87e-18 Breast cancer; TGCT cis rs4733781 0.527 rs7002892 chr8:131235135 A/T cg16277922 chr8:131349729 ASAP1 0.39 5.52 0.44 1.92e-7 Tuberculosis; TGCT cis rs651907 0.557 rs13081846 chr3:101383321 T/C cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs7193541 0.682 rs28681530 chr16:74682496 C/T cg01733217 chr16:74700730 RFWD3 1.0 13.51 0.77 3.91e-26 Multiple myeloma; TGCT cis rs4862750 0.758 rs2375915 chr4:187896255 A/C cg03452623 chr4:187889614 NA -0.36 -5.19 -0.42 8.48e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.861 rs4795377 chr17:37669056 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.88 -0.4 3.2e-6 Glomerular filtration rate (creatinine); TGCT cis rs6089829 0.962 rs3746747 chr20:61667631 T/C cg08045932 chr20:61659980 NA 0.48 9.1 0.63 1.91e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs6831352 0.918 rs7669636 chr4:100059312 G/A cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs13108904 0.870 rs11727987 chr4:1261435 A/G cg00684032 chr4:1343700 KIAA1530 0.22 4.83 0.4 3.99e-6 Obesity-related traits; TGCT cis rs950027 0.584 rs1145086 chr15:45654327 A/G cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs61656020 1 rs61656020 chr16:1882221 C/G cg26617929 chr16:1858877 NA -0.27 -4.8 -0.4 4.42e-6 Ankle injury; TGCT cis rs2120019 1.000 rs2415253 chr15:75375699 A/G cg17294928 chr15:75287854 SCAMP5 -0.86 -6.62 -0.51 9.55e-10 Blood trace element (Zn levels); TGCT cis rs11673344 0.523 rs7245520 chr19:37527318 A/G cg08039142 chr19:36980659 ZNF566 0.49 4.5 0.37 1.57e-5 Obesity-related traits; TGCT cis rs9969804 0.682 rs10761168 chr9:95505560 A/G cg13940029 chr9:95239186 CENPP;ASPN -0.17 -4.45 -0.37 1.92e-5 Height; TGCT cis rs2050392 0.624 rs303447 chr10:30728464 T/C cg18806716 chr10:30721971 MAP3K8 -0.7 -9.39 -0.64 3.84e-16 Inflammatory bowel disease; TGCT cis rs79349575 0.783 rs9912829 chr17:46982749 G/C cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT cis rs10984561 0.881 rs10984556 chr9:122247734 T/G cg14242995 chr9:122249943 NA 0.75 6.41 0.5 2.7e-9 Pulmonary function decline; TGCT cis rs11105298 0.786 rs10858867 chr12:89851166 C/T cg00757033 chr12:89920650 WDR51B 0.34 5.37 0.43 3.75e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs77741769 0.571 rs869781 chr12:121340246 T/C cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs10751667 0.666 rs7394427 chr11:970405 G/A cg06064525 chr11:970664 AP2A2 -0.36 -8.28 -0.6 1.67e-13 Alzheimer's disease (late onset); TGCT cis rs7945705 0.869 rs4909952 chr11:8963946 A/G cg21881798 chr11:8931708 C11orf17;ST5 0.46 5.2 0.42 8.11e-7 Hemoglobin concentration; TGCT cis rs8030485 0.756 rs2102999 chr15:79410710 C/T cg17916960 chr15:79447300 NA -0.35 -4.96 -0.41 2.31e-6 Left ventricle wall thickness; TGCT cis rs17206232 0.534 rs72760572 chr5:64692640 T/C cg09571848 chr5:64330935 NA -0.31 -4.46 -0.37 1.82e-5 Schizophrenia; TGCT cis rs3015497 0.789 rs8003372 chr14:51102351 G/A cg04730355 chr14:51134070 SAV1 -0.64 -6.26 -0.49 5.8e-9 Mean platelet volume; TGCT cis rs11096990 0.593 rs35552004 chr4:39172534 C/T cg20847110 chr4:39482781 LOC401127 0.17 4.96 0.41 2.3e-6 Cognitive function; TGCT cis rs7000551 0.751 rs2100291 chr8:22374551 C/T cg12081754 chr8:22256438 SLC39A14 0.31 5.0 0.41 1.9e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs904251 0.737 rs914347 chr6:37484970 A/C cg08126542 chr6:37504118 NA -0.41 -5.45 -0.44 2.57e-7 Cognitive performance; TGCT cis rs9611519 0.780 rs5751071 chr22:41656332 G/A cg13695892 chr22:41940480 POLR3H -0.65 -6.2 -0.49 7.73e-9 Neuroticism; TGCT cis rs10504229 1.000 rs72652906 chr8:58188360 C/A cg22535103 chr8:58192502 C8orf71 -0.42 -5.39 -0.44 3.49e-7 Developmental language disorder (linguistic errors); TGCT cis rs9486715 0.830 rs2255552 chr6:96999643 A/G cg06623918 chr6:96969491 KIAA0776 -1.06 -13.63 -0.77 2.02e-26 Headache; TGCT cis rs2282802 0.685 rs7737543 chr5:139646026 A/G cg01081189 chr5:139537190 NA 0.28 5.15 0.42 9.75e-7 Intelligence (multi-trait analysis); TGCT cis rs2019137 0.539 rs11123170 chr2:113978940 C/G cg19083407 chr2:113993142 PAX8;LOC440839;LOC654433 0.44 4.98 0.41 2.05e-6 Lymphocyte counts; TGCT cis rs2241685 0.540 rs11683007 chr2:1865262 C/G cg21862353 chr2:1801628 MYT1L -0.47 -4.71 -0.39 6.64e-6 Attention deficit hyperactivity disorder; TGCT cis rs9790314 0.846 rs9809522 chr3:160983768 G/C cg03342759 chr3:160939853 NMD3 -0.51 -5.66 -0.45 9.96e-8 Morning vs. evening chronotype; TGCT cis rs6933660 0.646 rs9383899 chr6:151781022 G/C cg14416726 chr6:151773293 C6orf211;RMND1 -1.05 -14.06 -0.78 1.99e-27 Menarche (age at onset); TGCT cis rs1801251 1.000 rs9653383 chr2:233670380 A/C cg08000102 chr2:233561755 GIGYF2 -0.64 -6.56 -0.51 1.34e-9 Coronary artery disease; TGCT cis rs6429082 0.782 rs704705 chr1:235612320 C/T cg26050004 chr1:235667680 B3GALNT2 -0.57 -4.88 -0.4 3.21e-6 Adiposity; TGCT cis rs11122272 0.670 rs2474632 chr1:231484361 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.71 -6.92 -0.53 2.18e-10 Hemoglobin concentration; TGCT cis rs8180040 0.934 rs62260710 chr3:47564462 C/G cg27129171 chr3:47204927 SETD2 -0.64 -7.34 -0.55 2.41e-11 Colorectal cancer; TGCT cis rs10791097 0.629 rs11222361 chr11:130731424 T/G cg12179176 chr11:130786555 SNX19 0.77 9.52 0.65 1.82e-16 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs4499344 0.521 rs259222 chr19:33136895 A/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.26 0.6 1.84e-13 Mean platelet volume; TGCT cis rs7824557 0.518 rs11783749 chr8:10802055 G/A cg27411982 chr8:10470053 RP1L1 -0.24 -5.02 -0.41 1.78e-6 Retinal vascular caliber; TGCT cis rs3812049 0.737 rs1993878 chr5:127476971 C/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.6 5.67 0.45 9.62e-8 Lymphocyte counts;Red cell distribution width; TGCT cis rs2742417 0.904 rs2373047 chr3:45747497 C/A cg04837898 chr3:45731254 SACM1L -0.55 -5.68 -0.45 9.22e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs6089584 0.606 rs2273989 chr20:60579138 G/A cg06108461 chr20:60628389 TAF4 -0.4 -5.02 -0.41 1.73e-6 Body mass index; TGCT cis rs611744 0.870 rs635941 chr8:109235457 G/A cg21045802 chr8:109455806 TTC35 0.7 6.26 0.49 5.73e-9 Dupuytren's disease; TGCT cis rs9902453 0.933 rs60694493 chr17:28473256 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs12477438 0.520 rs6708576 chr2:99801308 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 1.04 12.84 0.76 1.57e-24 Chronic sinus infection; TGCT cis rs9549367 0.789 rs9604040 chr13:113910611 A/G cg00898013 chr13:113819073 PROZ 0.37 4.66 0.39 7.87e-6 Platelet distribution width; TGCT cis rs9902453 0.808 rs4595850 chr17:28206326 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.8 7.31 0.55 2.9100000000000002e-11 Coffee consumption (cups per day); TGCT cis rs7772486 0.754 rs6921073 chr6:146144377 G/A cg23711669 chr6:146136114 FBXO30 0.9 10.15 0.67 5.45e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769707 0.681 rs2071902 chr22:50034538 G/C cg05373962 chr22:49881684 NA -0.31 -5.31 -0.43 4.99e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs3008870 1.000 rs2815351 chr1:67477980 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.01 9.9 0.66 2.23e-17 Lymphocyte percentage of white cells; TGCT cis rs7178572 0.568 rs11632966 chr15:77621805 A/C cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs2458413 1.000 rs2458413 chr8:105359432 C/T cg13045555 chr8:105342365 NA 0.38 5.93 0.47 2.78e-8 Paget's disease; TGCT cis rs28595532 0.841 rs115516095 chr4:119760096 A/C cg14228332 chr4:119757509 SEC24D 1.3 6.62 0.51 9.62e-10 Cannabis dependence symptom count; TGCT cis rs4819052 0.766 rs4819035 chr21:46645715 A/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.71 5.14 0.42 1.04e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2721811 0.593 rs2521768 chr7:24784403 C/T cg17569154 chr7:24781545 DFNA5 0.23 4.77 0.39 5.07e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1008375 1.000 rs7661631 chr4:17679751 T/C cg18681998 chr4:17616180 MED28 -0.83 -8.43 -0.6 7.25e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9467773 0.620 rs2451741 chr6:26629404 A/G cg26531700 chr6:26746687 NA 0.5 4.68 0.39 7.52e-6 Intelligence (multi-trait analysis); TGCT cis rs2762353 0.808 rs1165183 chr6:25836380 A/G cg12310025 chr6:25882481 NA -0.62 -6.42 -0.5 2.62e-9 Blood metabolite levels; TGCT cis rs2028201 1.000 rs2028201 chr2:201303010 A/C cg04781494 chr2:202047246 CASP10 -0.25 -4.43 -0.37 2.01e-5 Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis; TGCT cis rs7772486 0.754 rs9497434 chr6:146260753 C/T cg05347473 chr6:146136440 FBXO30 -0.52 -5.03 -0.41 1.67e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs35306767 0.909 rs12264390 chr10:959111 T/C cg20503657 chr10:835505 NA 0.68 9.49 0.65 2.12e-16 Eosinophil percentage of granulocytes; TGCT cis rs12682352 0.602 rs28399241 chr8:8663215 C/T cg06636001 chr8:8085503 FLJ10661 0.62 5.3 0.43 5.07e-7 Neuroticism; TGCT cis rs9677476 0.516 rs6755467 chr2:232044684 G/T cg07929768 chr2:232055508 NA -0.34 -5.38 -0.44 3.55e-7 Food antigen IgG levels; TGCT cis rs5750830 0.595 rs4821892 chr22:39795683 G/C cg24399712 chr22:39784796 NA -1.06 -12.44 -0.75 1.44e-23 Intelligence (multi-trait analysis); TGCT cis rs2072499 0.838 rs2758619 chr1:156162559 A/G cg25208724 chr1:156163844 SLC25A44 1.14 16.72 0.83 1.43e-33 Testicular germ cell tumor; TGCT trans rs2727020 0.636 rs11040368 chr11:49453602 C/A cg03929089 chr4:120376271 NA -0.77 -9.03 -0.63 2.74e-15 Coronary artery disease; TGCT cis rs769267 0.965 rs2916068 chr19:19516433 A/G cg03709012 chr19:19516395 GATAD2A 0.75 6.51 0.5 1.71e-9 Tonsillectomy; TGCT cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg00814883 chr7:100076585 TSC22D4 -0.89 -9.03 -0.63 2.76e-15 Platelet count; TGCT cis rs12142240 0.698 rs66516678 chr1:46810112 G/T cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs514406 0.755 rs11206015 chr1:53242187 T/C cg01802117 chr1:53393560 SCP2 0.44 5.34 0.43 4.33e-7 Monocyte count; TGCT cis rs3847687 1.000 rs3847688 chr12:131525310 C/T cg25772418 chr12:131519998 GPR133 -0.33 -6.1 -0.48 1.26e-8 Longevity; TGCT cis rs9911578 1.000 rs304296 chr17:56834229 G/T cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs2486012 1.000 rs1766968 chr1:44403042 T/C cg12908607 chr1:44402522 ARTN 0.78 6.04 0.48 1.68e-8 Intelligence (multi-trait analysis); TGCT cis rs67072384 0.748 rs6592484 chr11:72464470 C/T cg03713592 chr11:72463424 ARAP1 -0.88 -4.77 -0.39 5.04e-6 Alloimmunization response to red blood cell transfusion in sickle cell anemia; TGCT cis rs7811142 1.000 rs6962151 chr7:100028484 T/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs6570726 0.577 rs406868 chr6:145809983 C/T cg05347473 chr6:146136440 FBXO30 0.62 5.75 0.46 6.64e-8 Lobe attachment (rater-scored or self-reported); TGCT trans rs1005277 0.505 rs719569 chr10:38154415 T/G cg17830980 chr10:43048298 ZNF37B 0.74 8.59 0.61 3.11e-14 Extrinsic epigenetic age acceleration; TGCT cis rs9811920 0.641 rs58704213 chr3:99690331 T/C cg07805332 chr3:99536008 MIR548G;C3orf26 0.43 5.12 0.42 1.14e-6 Axial length; TGCT cis rs208520 0.837 rs208488 chr6:66926902 C/T cg07460842 chr6:66804631 NA -0.94 -9.3 -0.64 6.32e-16 Exhaled nitric oxide output; TGCT cis rs6540559 0.546 rs735694 chr1:210034029 T/C cg23283495 chr1:209979779 IRF6 0.67 4.99 0.41 1.96e-6 Cleft lip with or without cleft palate; TGCT cis rs12681288 0.782 rs12544713 chr8:1026697 C/T cg04851639 chr8:1020857 NA -0.32 -5.75 -0.46 6.63e-8 Schizophrenia; TGCT cis rs72781680 0.898 rs72786279 chr2:24063266 C/T cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs28386778 0.897 rs2584642 chr17:61942427 T/C cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.73 -0.39 5.93e-6 Prudent dietary pattern; TGCT cis rs3011225 0.691 rs3791102 chr1:44366617 C/T cg12908607 chr1:44402522 ARTN -0.66 -8.12 -0.59 3.95e-13 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs769267 1.000 rs1009136 chr19:19440428 A/G cg19010396 chr19:19431384 KIAA0892;SF4 -0.53 -4.5 -0.37 1.55e-5 Tonsillectomy; TGCT cis rs910316 1.000 rs12889309 chr14:75593902 C/T cg11812906 chr14:75593930 NEK9 0.74 7.37 0.55 2.12e-11 Height; TGCT cis rs1008375 0.932 rs11935124 chr4:17668200 G/A cg18681998 chr4:17616180 MED28 -0.87 -8.96 -0.63 4.13e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6933660 0.721 rs2128945 chr6:151767907 A/G cg10883421 chr6:151773342 RMND1;C6orf211 0.72 7.31 0.55 2.83e-11 Menarche (age at onset); TGCT cis rs4665809 1.000 rs4233708 chr2:26291345 C/T cg22920501 chr2:26401640 FAM59B -0.74 -6.4 -0.5 2.86e-9 Gut microbiome composition (summer); TGCT cis rs2836974 0.627 rs7278985 chr21:40653767 C/T cg11890956 chr21:40555474 PSMG1 -0.76 -7.45 -0.56 1.39e-11 Cognitive function; TGCT cis rs10832169 0.967 rs2178241 chr11:14072994 G/A cg04547675 chr11:13986162 SPON1 0.51 4.51 0.38 1.49e-5 Blood protein levels; TGCT cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg21280719 chr6:42927975 GNMT -0.37 -4.52 -0.38 1.41e-5 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs7267979 1.000 rs2500405 chr20:25360826 A/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6964587 0.692 rs418 chr7:91583334 C/T cg17063962 chr7:91808500 NA -0.75 -7.1 -0.54 8.63e-11 Breast cancer; TGCT cis rs28386778 0.897 rs7501614 chr17:61802612 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs2842992 0.714 rs2475564 chr6:160123673 A/G cg11366901 chr6:160182831 ACAT2 0.91 6.33 0.49 4.04e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs4563143 0.675 rs73029042 chr19:29267979 A/T cg12667521 chr19:29218732 NA 0.54 5.72 0.46 7.65e-8 Methadone dose in opioid dependence; TGCT cis rs10791097 0.748 rs2282579 chr11:130735482 C/T cg14779329 chr11:130786720 SNX19 0.28 4.96 0.41 2.31e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs8177253 1.000 rs8177240 chr3:133477701 T/G cg08439880 chr3:133502540 NA -0.31 -5.75 -0.46 6.41e-8 Iron status biomarkers; TGCT cis rs3733585 0.753 rs12500805 chr4:10017979 C/T cg00071950 chr4:10020882 SLC2A9 0.69 8.25 0.6 1.95e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs11209002 0.592 rs4655672 chr1:67553543 C/T cg02640540 chr1:67518911 SLC35D1 0.55 4.65 0.39 8.42e-6 Crohn's disease; TGCT cis rs7666738 0.830 rs6846739 chr4:99016647 G/A cg18180107 chr4:99064573 C4orf37 0.54 5.03 0.41 1.7e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs28386778 0.830 rs2597637 chr17:61875066 T/G cg23090583 chr17:61904693 PSMC5;FTSJ3 1.11 16.05 0.82 4.59e-32 Prudent dietary pattern; TGCT cis rs2229238 0.866 rs112231452 chr1:154504900 G/A cg13067139 chr1:155221277 FAM189B 0.2 4.69 0.39 6.95e-6 Coronary heart disease; TGCT cis rs4851254 0.517 rs13020141 chr2:100653842 G/A cg07810366 chr2:100720526 AFF3 -0.46 -4.64 -0.38 8.78e-6 Intelligence (multi-trait analysis); TGCT cis rs12188164 0.965 rs56146525 chr5:442571 A/C cg21144161 chr5:423903 AHRR 0.25 4.79 0.4 4.59e-6 Cystic fibrosis severity; TGCT cis rs3820068 0.705 rs11584398 chr1:15880275 G/A cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs10498514 1.000 rs117727667 chr14:65028278 T/A cg25134081 chr14:64931936 AKAP5 1.13 4.63 0.38 9.22e-6 Cognitive performance; TGCT cis rs6589563 0.737 rs61905086 chr11:116614863 T/C cg01124546 chr11:117515332 DSCAML1 -0.41 -4.5 -0.37 1.55e-5 Eosinophil counts; TGCT cis rs3087591 0.960 rs2905802 chr17:29520084 T/C cg24425628 chr17:29625626 OMG;NF1 0.46 7.39 0.55 1.91e-11 Hip circumference; TGCT cis rs999943 0.774 rs12212284 chr6:33640874 T/A cg14003231 chr6:33640908 ITPR3 0.4 4.88 0.4 3.19e-6 Obesity (extreme); TGCT cis rs78456975 0.527 rs4073862 chr2:1563433 A/G cg12573674 chr2:1569213 NA -0.45 -4.84 -0.4 3.84e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs614226 0.938 rs787824 chr12:120924638 A/G cg01236616 chr12:121019343 POP5 -1.11 -12.2 -0.74 5.61e-23 Type 1 diabetes nephropathy; TGCT cis rs7508 0.511 rs208026 chr8:17878155 A/G cg01800426 chr8:17659068 MTUS1 -0.62 -5.08 -0.42 1.33e-6 Atrial fibrillation; TGCT cis rs7017914 0.783 rs13252584 chr8:71689031 A/G cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.98 -0.41 2.09e-6 Bone mineral density; TGCT cis rs10504229 1.000 rs66672857 chr8:58179817 G/C cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs1568889 1.000 rs7951681 chr11:28273894 G/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.81 7.87 0.58 1.54e-12 Bipolar disorder; TGCT cis rs9303401 1.000 rs1390006 chr17:56890663 C/T cg12560992 chr17:57184187 TRIM37 -0.54 -5.61 -0.45 1.26e-7 Cognitive test performance; TGCT trans rs10504390 0.585 rs80151640 chr8:66537841 C/T cg18118147 chr19:51128640 SYT3 -0.77 -6.85 -0.52 2.99e-10 IgG glycosylation; TGCT cis rs9894429 0.682 rs7406360 chr17:79591545 G/A cg18240062 chr17:79603768 NPLOC4 0.84 9.67 0.66 8.1e-17 Eye color traits; TGCT cis rs12497850 0.864 rs4521268 chr3:49137904 G/T cg16497277 chr3:49208875 KLHDC8B -0.49 -4.48 -0.37 1.68e-5 Parkinson's disease; TGCT trans rs4650994 0.544 rs4075631 chr1:178506594 C/A cg05059571 chr16:84539110 KIAA1609 -0.55 -11.44 -0.72 3.86e-21 HDL cholesterol levels;HDL cholesterol; TGCT cis rs9383153 0.590 rs2072736 chr6:16328068 T/C cg03173502 chr6:15505345 JARID2 0.83 4.59 0.38 1.06e-5 Gambling; TGCT cis rs473651 1.000 rs473651 chr2:239335401 A/C cg08773314 chr2:239334832 ASB1 0.47 7.96 0.58 9.43e-13 Multiple system atrophy; TGCT cis rs3749237 0.964 rs7431078 chr3:49808190 G/A cg07636037 chr3:49044803 WDR6 0.64 5.63 0.45 1.13e-7 Resting heart rate; TGCT cis rs28386778 0.897 rs2854208 chr17:61946885 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs2243480 1.000 rs313799 chr7:65494330 A/G cg07424592 chr7:64974309 NA 1.4 8.42 0.6 7.87e-14 Diabetic kidney disease; TGCT cis rs5750830 0.649 rs4821895 chr22:39823015 A/G cg05872129 chr22:39784769 NA -1.01 -11.06 -0.7 3.4e-20 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.659 rs28530678 chr22:41934961 G/C cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs2594989 0.779 rs2447603 chr3:11590261 T/C cg00170343 chr3:11313890 ATG7 -0.71 -5.4 -0.44 3.26e-7 Circulating chemerin levels; TGCT cis rs11122272 0.735 rs2474634 chr1:231487017 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.77 -0.52 4.54e-10 Hemoglobin concentration; TGCT cis rs11673344 0.504 rs7245882 chr19:37580415 A/G cg08039142 chr19:36980659 ZNF566 -0.5 -4.63 -0.38 8.95e-6 Obesity-related traits; TGCT cis rs6495122 0.532 rs2470890 chr15:75047426 C/T cg10253484 chr15:75165896 SCAMP2 -0.69 -6.0 -0.47 2.05e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs644799 1.000 rs2508289 chr11:95624669 A/G cg03916912 chr11:95522834 CEP57;FAM76B 0.84 9.93 0.67 1.91e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1008375 0.966 rs6449313 chr4:17588320 A/G cg10189774 chr4:17578691 LAP3 0.63 5.52 0.44 1.9e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9611565 0.729 rs203320 chr22:41913477 T/C cg17554472 chr22:41940697 POLR3H -0.44 -4.97 -0.41 2.15e-6 Vitiligo; TGCT cis rs1868673 0.679 rs4323025 chr3:150161522 A/G cg24290546 chr3:150134309 TSC22D2 0.24 4.53 0.38 1.37e-5 Waist circumference; TGCT cis rs4862307 0.964 rs6840005 chr4:184998350 C/T cg06737308 chr4:185021514 ENPP6 0.44 6.38 0.5 3.12e-9 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs7572733 0.534 rs700667 chr2:198677508 T/C cg00792783 chr2:198669748 PLCL1 0.56 5.08 0.42 1.35e-6 Dermatomyositis; TGCT cis rs854765 0.624 rs8078756 chr17:17744725 T/C cg04398451 chr17:18023971 MYO15A 0.32 4.76 0.39 5.24e-6 Total body bone mineral density; TGCT cis rs2836974 0.897 rs8128102 chr21:40606414 G/A cg11644478 chr21:40555479 PSMG1 1.0 10.6 0.69 4.32e-19 Cognitive function; TGCT cis rs2932538 0.922 rs12137107 chr1:113127437 A/G cg22162597 chr1:113214053 CAPZA1 0.27 5.98 0.47 2.24e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9549260 0.755 rs9532571 chr13:41218670 C/T cg21288729 chr13:41239152 FOXO1 1.01 11.06 0.7 3.29e-20 Red blood cell count; TGCT cis rs11107903 1.000 rs11107903 chr12:95507971 G/A cg10621809 chr12:95840313 NA 0.7 4.61 0.38 9.89e-6 Coronary artery disease; TGCT cis rs9916302 0.904 rs10432031 chr17:37397852 G/A cg07936489 chr17:37558343 FBXL20 -0.65 -5.26 -0.43 6e-7 Glomerular filtration rate (creatinine); TGCT cis rs10464366 0.544 rs9639812 chr7:39192058 C/T cg15212455 chr7:39170539 POU6F2 0.3 6.66 0.51 8.11e-10 IgG glycosylation; TGCT cis rs13191362 0.507 rs2849534 chr6:163144657 T/A cg06582575 chr6:163149167 PACRG;PARK2 -0.58 -5.35 -0.43 4.05e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs1129187 0.755 rs9471985 chr6:42941324 T/C cg17345569 chr6:42928274 GNMT -0.48 -4.95 -0.41 2.35e-6 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs453301 0.512 rs2921381 chr8:8895401 T/A cg00184457 chr8:8946301 NA 0.24 4.54 0.38 1.32e-5 Joint mobility (Beighton score); TGCT cis rs7169223 0.653 rs1564499 chr15:79084808 C/T cg03762349 chr15:79060523 ADAMTS7 0.22 4.61 0.38 9.96e-6 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs7666738 0.830 rs6532720 chr4:99043781 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs74544699 1.000 rs80127839 chr4:74837229 A/C cg16072462 chr4:74847758 PF4 0.76 4.86 0.4 3.49e-6 Growth-regulated protein alpha levels; TGCT cis rs28595532 0.764 rs115298416 chr4:119565383 C/T cg21605333 chr4:119757512 SEC24D 1.36 7.24 0.55 4.15e-11 Cannabis dependence symptom count; TGCT cis rs854765 0.583 rs9912895 chr17:17826020 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.73 -7.63 -0.57 5.33e-12 Total body bone mineral density; TGCT cis rs7267979 0.903 rs6107015 chr20:25216764 G/A cg16686733 chr20:25566563 NINL 0.59 6.04 0.48 1.64e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9640161 0.659 rs7788316 chr7:150013995 A/T cg10018233 chr7:150070692 REPIN1 0.32 4.47 0.37 1.75e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs539096 0.872 rs10890255 chr1:44031493 A/G cg12908607 chr1:44402522 ARTN -0.48 -4.98 -0.41 2.06e-6 Intelligence (multi-trait analysis); TGCT cis rs6988636 1.000 rs13260626 chr8:124190317 C/T cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs3785574 0.962 rs2727329 chr17:61924566 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.48 0.44 2.25e-7 Height; TGCT cis rs4711350 0.953 rs1547668 chr6:33775446 A/G cg18005901 chr6:33739558 LEMD2 -0.53 -5.66 -0.45 9.98e-8 Schizophrenia; TGCT cis rs7914558 0.966 rs7908280 chr10:104816947 C/G cg05855489 chr10:104503620 C10orf26 0.51 4.5 0.37 1.56e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs1609391 0.543 rs9828009 chr3:136631275 C/T cg15507776 chr3:136538369 TMEM22 0.66 6.84 0.52 3.27e-10 Neuroticism; TGCT cis rs11031096 0.711 rs1348309 chr11:4202000 A/T cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs28599928 0.920 rs17415203 chr22:43455592 A/G cg15811549 chr22:43485393 TTLL1 -0.93 -4.89 -0.4 3.04e-6 Breast cancer; TGCT cis rs911555 0.755 rs8010247 chr14:103933556 A/G cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs3733585 0.598 rs28677023 chr4:9958326 C/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6570726 0.791 rs370112 chr6:145859853 T/G cg13319975 chr6:146136371 FBXO30 -0.51 -4.6 -0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769765 0.671 rs138832 chr22:50178082 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -0.96 -9.26 -0.64 7.87e-16 Schizophrenia; TGCT cis rs35883536 0.528 rs1577511 chr1:101030859 G/A cg06223162 chr1:101003688 GPR88 0.43 8.41 0.6 8.23e-14 Monocyte count; TGCT cis rs873946 0.564 rs12242672 chr10:134555609 A/T cg05985448 chr10:134359359 INPP5A 0.22 4.73 0.39 6e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7666738 0.830 rs4699331 chr4:99059816 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.79 0.46 5.32e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6952808 0.692 rs60755037 chr7:2030104 G/A cg22963979 chr7:1858916 MAD1L1 -0.45 -7.41 -0.55 1.74e-11 Bipolar disorder and schizophrenia; TGCT cis rs595982 0.527 rs73061658 chr19:49372376 G/C cg17863274 chr19:49399704 TULP2 -0.47 -6.81 -0.52 3.78e-10 Red cell distribution width; TGCT cis rs12762955 0.687 rs4880470 chr10:1077480 G/A cg26597838 chr10:835615 NA -0.4 -5.08 -0.42 1.33e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs3796352 1.000 rs34244302 chr3:53102236 C/G cg15956490 chr3:53032818 SFMBT1 0.59 6.64 0.51 8.89e-10 Immune reponse to smallpox (secreted IL-2); TGCT trans rs214785 0.790 rs62192637 chr20:2260968 G/A cg24980040 chr10:1714535 ADARB2 0.46 6.62 0.51 9.65e-10 Basal cell carcinoma; TGCT cis rs587847 0.737 rs4924153 chr15:37666010 A/T cg00216138 chr15:37171175 LOC145845 -0.32 -4.8 -0.4 4.45e-6 Intraocular pressure; TGCT cis rs10207060 0.500 rs11884577 chr2:240702216 C/G cg15726768 chr2:241314588 NA -0.32 -4.58 -0.38 1.1e-5 Obesity-related traits; TGCT cis rs9942416 0.660 rs17649055 chr5:74984269 C/T cg19683494 chr5:74908142 NA 0.59 6.34 0.49 3.85e-9 Age-related disease endophenotypes; TGCT cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg10802521 chr3:52805072 NEK4 -0.7 -8.54 -0.61 4.07e-14 Bipolar disorder; TGCT cis rs16866061 0.962 rs16866045 chr2:225413020 G/A cg12698349 chr2:225449008 CUL3 1.0 9.83 0.66 3.23e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs13118159 0.527 rs6599308 chr4:1387780 A/G cg05025164 chr4:1340916 KIAA1530 0.8 6.42 0.5 2.68e-9 Longevity; TGCT cis rs7027203 0.557 rs2490997 chr9:96522109 C/T cg13679303 chr9:96623674 NA -0.53 -7.48 -0.56 1.18e-11 DNA methylation (variation); TGCT cis rs8038465 0.622 rs7182124 chr15:73915254 C/T cg15420318 chr15:73925796 NPTN 0.68 7.35 0.55 2.28e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7772486 0.790 rs9497427 chr6:146238302 T/A cg05347473 chr6:146136440 FBXO30 -0.5 -4.85 -0.4 3.68e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs5769765 0.913 rs4824111 chr22:50284305 A/G cg15316289 chr22:50310904 ALG12;CRELD2 -0.43 -6.37 -0.5 3.28e-9 Schizophrenia; TGCT cis rs7975161 0.572 rs11111919 chr12:104569918 C/A cg25273343 chr12:104657179 TXNRD1 -0.44 -5.61 -0.45 1.26e-7 Toenail selenium levels; TGCT cis rs603424 0.597 rs574122 chr10:102089174 C/A cg22671421 chr10:102507979 PAX2 0.59 4.71 0.39 6.63e-6 Phospholipid levels (plasma);Palmitic acid (16:0) levels;Palmitoleic acid (16:1n-7) levels;Mean platelet volume;Serum metabolite levels;Blood metabolite levels;Vaccenic acid (18:1n-7) levels;Metabolic traits;Coronary artery disease;Blood metabolite ratios;Glycerophospholipid levels; TGCT cis rs2688608 0.620 rs7080350 chr10:75577843 A/G cg15838173 chr10:75533400 FUT11 0.31 5.27 0.43 5.76e-7 Inflammatory bowel disease; TGCT cis rs854765 0.583 rs11869536 chr17:17826528 T/A cg09796270 chr17:17721594 SREBF1 0.24 4.7 0.39 6.83e-6 Total body bone mineral density; TGCT cis rs28595532 0.920 rs115850161 chr4:119732447 T/C cg14228332 chr4:119757509 SEC24D 1.32 6.38 0.5 3.2e-9 Cannabis dependence symptom count; TGCT cis rs2033711 0.870 rs7259841 chr19:58951123 T/C cg12042659 chr19:58951599 ZNF132 0.52 4.67 0.39 7.67e-6 Uric acid clearance; TGCT trans rs7613875 0.620 rs7430334 chr3:50078221 T/C cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs11971779 0.715 rs6943973 chr7:139029893 G/C cg07862535 chr7:139043722 LUC7L2 0.56 4.46 0.37 1.82e-5 Diisocyanate-induced asthma; TGCT cis rs453301 0.686 rs7814328 chr8:8876229 T/C cg15556689 chr8:8085844 FLJ10661 -0.62 -5.13 -0.42 1.07e-6 Joint mobility (Beighton score); TGCT cis rs11577318 0.579 rs35456934 chr1:26686864 G/A cg15090202 chr1:26687087 NA 0.59 4.58 0.38 1.1e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs1799949 0.965 rs11658499 chr17:41334749 C/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 5.06 0.41 1.45e-6 Menopause (age at onset); TGCT cis rs154659 0.887 rs154660 chr16:89667637 C/G cg01710450 chr16:89662404 CPNE7 -0.39 -6.89 -0.53 2.44e-10 Tanning; TGCT trans rs9329221 0.655 rs656319 chr8:9814411 A/G cg15556689 chr8:8085844 FLJ10661 -0.75 -6.79 -0.52 4.05e-10 Neuroticism; TGCT cis rs77972916 0.505 rs6736400 chr2:43500804 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -5.7 -0.46 8.41e-8 Granulocyte percentage of myeloid white cells; TGCT cis rs28386778 0.966 rs2008053 chr17:61954918 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.05 0.41 1.54e-6 Prudent dietary pattern; TGCT cis rs11776272 0.927 rs11135789 chr8:21878607 C/T cg17168535 chr8:21777572 XPO7 -0.64 -5.9 -0.47 3.21e-8 Obesity-related traits; TGCT cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 0.8 5.52 0.44 1.89e-7 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs1865760 0.532 rs2006736 chr6:26086017 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.49 0.56 1.15e-11 Height; TGCT cis rs17270561 0.779 rs1165200 chr6:25875212 C/T cg17042849 chr6:26104293 HIST1H4C 0.65 4.66 0.39 7.87e-6 Iron status biomarkers; TGCT cis rs9457247 0.935 rs2149093 chr6:167373045 T/C cg25258033 chr6:167368657 RNASET2 -0.19 -4.58 -0.38 1.1e-5 Crohn's disease; TGCT cis rs7264396 0.561 rs6058388 chr20:34571846 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.28 -4.94 -0.41 2.49e-6 Total cholesterol levels; TGCT cis rs317689 0.718 rs160827 chr12:69770147 G/A cg11871910 chr12:69753446 YEATS4 0.55 4.72 0.39 6.38e-6 Response to diuretic therapy; TGCT cis rs28386778 0.865 rs2727276 chr17:61929709 G/A cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs7100689 0.577 rs2236569 chr10:82043576 G/A cg01528321 chr10:82214614 TSPAN14 0.66 6.47 0.5 2.02e-9 Post bronchodilator FEV1; TGCT cis rs7944584 0.511 rs10838731 chr11:47607135 C/T cg20307385 chr11:47447363 PSMC3 0.88 8.62 0.61 2.57e-14 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs10883723 0.962 rs1056738 chr10:104236481 G/A cg05855489 chr10:104503620 C10orf26 -0.55 -4.68 -0.39 7.42e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs597539 0.689 rs596874 chr11:68630874 C/T cg21963583 chr11:68658836 MRPL21 -0.37 -6.22 -0.49 7.08e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9814567 1.000 rs10935120 chr3:134233092 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.86 8.53 0.61 4.26e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1568889 0.838 rs7125749 chr11:28154692 A/T cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.01 0.7 4.33e-20 Bipolar disorder; TGCT cis rs7829975 0.567 rs6601273 chr8:8796519 T/G cg06636001 chr8:8085503 FLJ10661 -0.7 -6.19 -0.49 8.23e-9 Mood instability; TGCT cis rs12541335 0.639 rs4872468 chr8:22179844 G/C cg09517075 chr8:22133004 PIWIL2 0.25 5.0 0.41 1.93e-6 Hypertriglyceridemia; TGCT cis rs9915657 0.870 rs12941066 chr17:70141226 C/T cg06234051 chr17:70120541 SOX9 -0.25 -4.92 -0.4 2.67e-6 Thyroid hormone levels; TGCT cis rs6138458 1.000 rs2387362 chr20:24899906 C/T cg26195577 chr20:24973756 C20orf3 -1.2 -12.04 -0.73 1.35e-22 Blood protein levels; TGCT cis rs7953508 0.506 rs2200160 chr12:93963873 C/T cg18151635 chr12:93972918 NA -0.2 -4.65 -0.39 8.34e-6 Pubertal anthropometrics; TGCT cis rs2012796 1.000 rs10450894 chr14:81825172 T/A cg02996355 chr14:81879375 NA 0.47 4.61 0.38 9.68e-6 Night sleep phenotypes; TGCT cis rs6088590 0.561 rs6059932 chr20:33175466 C/T cg06115741 chr20:33292138 TP53INP2 0.51 4.47 0.37 1.76e-5 Coronary artery disease; TGCT cis rs4478858 0.660 rs10798844 chr1:31819128 A/G cg07478791 chr1:31886160 SERINC2 -0.5 -4.71 -0.39 6.56e-6 Alcohol dependence; TGCT cis rs7246657 1.000 rs7247672 chr19:37743928 A/G cg18154014 chr19:37997991 ZNF793 0.84 5.58 0.45 1.46e-7 Coronary artery calcification; TGCT cis rs9303401 0.659 rs17222691 chr17:56771096 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.99 0.47 2.08e-8 Cognitive test performance; TGCT cis rs1971762 0.563 rs4759285 chr12:54079513 G/T cg16917193 chr12:54089295 NA 1.36 17.86 0.85 4.33e-36 Height; TGCT cis rs7223966 1.000 rs9895920 chr17:61852719 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 4.89 0.4 3.12e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3806843 0.966 rs11741994 chr5:140145949 G/A cg19875535 chr5:140030758 IK 0.37 6.23 0.49 6.53e-9 Depressive symptoms (multi-trait analysis); TGCT cis rs55962025 0.883 rs82334 chr4:3225371 A/C cg06533319 chr4:3265114 C4orf44 0.24 4.68 0.39 7.31e-6 Parental longevity (mother's age at death); TGCT cis rs6540559 0.673 rs4556361 chr1:210019654 C/G cg22029157 chr1:209979665 IRF6 -0.67 -4.95 -0.41 2.33e-6 Cleft lip with or without cleft palate; TGCT cis rs896854 1.000 rs7003387 chr8:95961979 C/G cg16049864 chr8:95962084 TP53INP1 -0.76 -11.14 -0.71 2.13e-20 Type 2 diabetes; TGCT cis rs9303401 0.659 rs12600349 chr17:57054245 A/G cg02118635 chr17:56770003 RAD51C;TEX14 -0.6 -5.97 -0.47 2.36e-8 Cognitive test performance; TGCT cis rs28735056 0.572 rs4799100 chr18:77640207 A/G cg20368463 chr18:77673604 PQLC1 -0.46 -5.6 -0.45 1.31e-7 Schizophrenia; TGCT cis rs2562456 0.837 rs11085462 chr19:21750251 C/G cg25650185 chr19:21324782 ZNF431 -0.66 -5.86 -0.47 3.92e-8 Pain; TGCT cis rs2486012 1.000 rs2906459 chr1:44335657 A/C cg12908607 chr1:44402522 ARTN -0.69 -5.57 -0.45 1.49e-7 Intelligence (multi-trait analysis); TGCT cis rs9549367 0.713 rs1323315 chr13:113859658 T/C cg00898013 chr13:113819073 PROZ 0.51 6.95 0.53 1.84e-10 Platelet distribution width; TGCT cis rs7681440 0.874 rs1442151 chr4:90775491 T/A cg20003494 chr4:90757398 SNCA -0.56 -5.35 -0.43 4.11e-7 Dementia with Lewy bodies; TGCT cis rs10858047 0.883 rs6537841 chr1:115200808 A/G cg12756093 chr1:115239321 AMPD1 -0.47 -4.96 -0.41 2.27e-6 Autism; TGCT cis rs936229 0.861 rs12441505 chr15:75107311 A/C cg10253484 chr15:75165896 SCAMP2 -0.66 -5.34 -0.43 4.28e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs929596 0.785 rs17864701 chr2:234652717 C/T cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.33 -5.23 -0.42 7.05e-7 Total bilirubin levels in HIV-1 infection; TGCT cis rs6909279 0.933 rs9478219 chr6:151882362 T/G cg14416726 chr6:151773293 C6orf211;RMND1 0.53 4.64 0.38 8.58e-6 Bone mineral density; TGCT cis rs2797160 1.000 rs1935773 chr6:125996475 A/G cg05901451 chr6:126070800 HEY2 -0.73 -6.6 -0.51 1.09e-9 Endometrial cancer; TGCT cis rs7091068 0.518 rs1572772 chr10:95432862 A/G cg20715218 chr10:95462985 C10orf4 -0.5 -5.35 -0.43 4.12e-7 Urinary tract infection frequency; TGCT cis rs2836974 0.932 rs2234543 chr21:40572072 G/A cg11644478 chr21:40555479 PSMG1 1.01 10.47 0.69 8.99e-19 Cognitive function; TGCT cis rs350251 0.868 rs350278 chr16:12232402 T/C cg01574788 chr16:12184133 SNX29 0.34 4.48 0.37 1.67e-5 Intelligence (multi-trait analysis); TGCT cis rs9325144 0.671 rs7485963 chr12:38768254 C/G cg26384229 chr12:38710491 ALG10B -0.62 -5.77 -0.46 5.9e-8 Morning vs. evening chronotype; TGCT cis rs7772486 0.754 rs4895682 chr6:146062861 G/A cg05347473 chr6:146136440 FBXO30 -0.53 -4.91 -0.4 2.81e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs1878931 0.624 rs39728 chr16:3453076 A/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.69 5.77 0.46 6.01e-8 Body mass index (adult); TGCT cis rs3760775 1.000 rs3760775 chr19:5841356 A/C cg25387410 chr19:5844109 FUT3 0.38 5.79 0.46 5.51e-8 Vitamin B12 levels;Elevated serum carcinoembryonic antigen levels;Tumor biomarkers; TGCT cis rs12681288 0.523 rs111782857 chr8:962486 T/C cg04851639 chr8:1020857 NA -0.3 -5.08 -0.41 1.36e-6 Schizophrenia; TGCT cis rs10504229 0.728 rs17804822 chr8:58156276 T/C cg20607798 chr8:58055168 NA 0.49 4.56 0.38 1.23e-5 Developmental language disorder (linguistic errors); TGCT cis rs68170813 0.559 rs11761181 chr7:106954879 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs7666738 0.830 rs9992639 chr4:98940400 G/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6921919 0.583 rs16894108 chr6:28401790 A/G cg18815343 chr6:28367644 ZSCAN12 -0.55 -5.16 -0.42 9.34e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9611565 0.649 rs126092 chr22:42178441 A/G cg06481639 chr22:41940642 POLR3H 0.56 4.64 0.38 8.66e-6 Vitiligo; TGCT cis rs56309584 0.597 rs78296773 chr17:8167962 G/T cg08322244 chr17:8066669 VAMP2 -0.56 -5.16 -0.42 9.58e-7 Initial pursuit acceleration; TGCT cis rs2204008 0.623 rs1315348 chr12:38163044 G/A cg26384229 chr12:38710491 ALG10B -0.58 -5.08 -0.42 1.33e-6 Bladder cancer; TGCT cis rs6141769 0.542 rs6058819 chr20:31303942 T/C cg13636640 chr20:31349939 DNMT3B -0.51 -4.48 -0.37 1.68e-5 Subjective well-being; TGCT cis rs4631830 0.896 rs7088225 chr10:51522120 T/C cg10326726 chr10:51549505 MSMB 0.23 4.67 0.39 7.81e-6 Prostate-specific antigen levels; TGCT cis rs6988636 1.000 rs7002332 chr8:124185442 G/C cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs1395 0.778 rs11693660 chr2:27468856 T/C cg14242246 chr2:27434262 C2orf28;SLC5A6 0.7 9.35 0.64 4.81e-16 Blood metabolite levels; TGCT cis rs2289583 0.544 rs6495132 chr15:75255322 C/T cg10253484 chr15:75165896 SCAMP2 0.58 5.23 0.43 6.95e-7 Systemic lupus erythematosus; TGCT cis rs514406 0.929 rs12354395 chr1:53327663 A/G cg08736216 chr1:53307985 ZYG11A -0.3 -5.99 -0.47 2.09e-8 Monocyte count; TGCT cis rs35771425 0.642 rs11586974 chr1:211464115 A/G cg25617285 chr1:211431773 RCOR3 0.47 5.39 0.44 3.44e-7 Educational attainment (years of education); TGCT cis rs9911578 0.704 rs72628393 chr17:56585314 A/T cg12560992 chr17:57184187 TRIM37 -0.76 -9.0 -0.63 3.28e-15 Intelligence (multi-trait analysis); TGCT cis rs59698941 0.527 rs7719428 chr5:132180919 C/G cg21474247 chr5:131268130 NA -0.31 -4.83 -0.4 3.86e-6 Apolipoprotein A-IV levels; TGCT cis rs36051895 0.632 rs1571438 chr9:5140313 A/C cg02405213 chr9:5042618 JAK2 -0.75 -10.5 -0.69 7.82e-19 Pediatric autoimmune diseases; TGCT cis rs2836974 0.605 rs2836971 chr21:40652040 A/C cg17971929 chr21:40555470 PSMG1 -0.7 -6.6 -0.51 1.1e-9 Cognitive function; TGCT cis rs4285028 0.747 rs7648340 chr3:121426188 G/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs7727544 0.606 rs72795121 chr5:131638324 T/A cg14196790 chr5:131705035 SLC22A5 0.36 4.87 0.4 3.3e-6 Blood metabolite levels; TGCT cis rs7618915 0.547 rs34017441 chr3:52742413 T/C cg07507251 chr3:52567010 NT5DC2 0.46 6.63 0.51 9.3e-10 Bipolar disorder; TGCT cis rs61931739 0.500 rs6488209 chr12:34319309 A/G cg06521331 chr12:34319734 NA -0.35 -5.74 -0.46 6.71e-8 Morning vs. evening chronotype; TGCT cis rs909002 0.800 rs7529064 chr1:32105192 C/A cg11573219 chr1:32083031 HCRTR1 -0.43 -5.6 -0.45 1.33e-7 Intelligence (multi-trait analysis); TGCT cis rs1552244 0.608 rs3732962 chr3:10048951 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.33 -4.95 -0.41 2.39e-6 Alzheimer's disease; TGCT cis rs3849570 0.643 rs10779987 chr3:81970856 C/T cg07356753 chr3:81810745 GBE1 -0.64 -5.62 -0.45 1.19e-7 Waist circumference;Body mass index; TGCT trans rs1814175 0.817 rs10128730 chr11:50023369 G/T cg11707556 chr5:10655725 ANKRD33B -0.37 -7.26 -0.55 3.77e-11 Height; TGCT cis rs644799 0.544 rs525087 chr11:95632266 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.49 4.98 0.41 2.08e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs6088580 0.634 rs6059867 chr20:33078103 C/T cg06115741 chr20:33292138 TP53INP2 0.54 4.82 0.4 4.11e-6 Glomerular filtration rate (creatinine); TGCT cis rs875971 0.965 rs9969301 chr7:65781655 G/A cg11764359 chr7:65958608 NA -0.61 -5.51 -0.44 1.96e-7 Aortic root size; TGCT trans rs7819412 0.645 rs10156356 chr8:11046209 T/C cg15556689 chr8:8085844 FLJ10661 -0.76 -6.86 -0.52 2.97e-10 Triglycerides; TGCT cis rs6880778 0.505 rs7730693 chr5:40373105 A/G cg01087697 chr5:40835557 RPL37 0.53 4.83 0.4 3.95e-6 Inflammatory bowel disease; TGCT cis rs2836974 0.568 rs371625 chr21:40535271 A/G cg11644478 chr21:40555479 PSMG1 -0.61 -5.74 -0.46 6.75e-8 Cognitive function; TGCT cis rs936229 0.654 rs762551 chr15:75041917 C/A cg10253484 chr15:75165896 SCAMP2 -0.59 -5.0 -0.41 1.89e-6 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs42648 0.869 rs3810890 chr7:89908833 G/T cg25739043 chr7:89950458 NA -0.73 -7.29 -0.55 3.15e-11 Homocysteine levels; TGCT cis rs9549367 0.713 rs9549691 chr13:113861606 A/C cg18105134 chr13:113819100 PROZ -0.46 -8.1 -0.59 4.35e-13 Platelet distribution width; TGCT cis rs6684514 0.885 rs12036837 chr1:156283895 A/C cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs11874712 1.000 rs9783884 chr18:43651133 A/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.53 5.11 0.42 1.19e-6 Migraine - clinic-based; TGCT cis rs2228479 0.867 rs62052168 chr16:89947203 G/A cg06558623 chr16:89946397 TCF25 0.57 6.52 0.51 1.62e-9 Skin colour saturation; TGCT cis rs6725041 0.766 rs13415721 chr2:213092242 C/T cg20637307 chr2:213403960 ERBB4 -0.51 -4.49 -0.37 1.64e-5 QT interval (ambient particulate matter interaction); TGCT cis rs10114408 0.959 rs2185110 chr9:96648679 A/C cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6952808 0.723 rs1107592 chr7:2041432 C/T cg22963979 chr7:1858916 MAD1L1 0.44 7.04 0.53 1.17e-10 Bipolar disorder and schizophrenia; TGCT trans rs2727020 0.514 rs4980444 chr11:49550764 T/A cg15704280 chr7:45808275 SEPT13 -0.61 -6.78 -0.52 4.26e-10 Coronary artery disease; TGCT cis rs2380220 0.606 rs4571572 chr6:96004823 T/C cg04719120 chr6:96025338 MANEA 0.58 4.53 0.38 1.35e-5 Behavioural disinhibition (generation interaction); TGCT cis rs7208859 0.623 rs12006 chr17:29110652 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs875971 0.798 rs7789615 chr7:65878661 A/G cg11764359 chr7:65958608 NA 0.54 5.02 0.41 1.73e-6 Aortic root size; TGCT cis rs6582630 0.513 rs11181246 chr12:38302670 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.31e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs2242116 0.796 rs2290546 chr3:46965197 C/G cg23352942 chr3:46931381 PTH1R -0.32 -4.53 -0.38 1.36e-5 Birth weight; TGCT cis rs2576037 0.583 rs9304336 chr18:44461687 T/C cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.58 -0.38 1.11e-5 Personality dimensions; TGCT cis rs8180040 0.966 rs922957 chr3:47422152 G/C cg27129171 chr3:47204927 SETD2 -0.64 -7.39 -0.55 1.89e-11 Colorectal cancer; TGCT cis rs6733011 0.500 rs885115 chr2:99446445 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.67 -0.39 7.65e-6 Bipolar disorder; TGCT cis rs589448 0.902 rs2603090 chr12:69777188 G/A cg14784868 chr12:69753453 YEATS4 0.9 10.6 0.69 4.47e-19 Cerebrospinal fluid biomarker levels; TGCT cis rs45430 1.000 rs364525 chr21:42745578 A/G cg22778903 chr21:42741698 MX2 -0.3 -5.01 -0.41 1.84e-6 Melanoma; TGCT cis rs7666738 0.830 rs7678567 chr4:99057346 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.830 rs1534318 chr4:98965058 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.48 0.56 1.18e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs13108904 0.935 rs1732102 chr4:1277924 T/C cg03303774 chr4:1407052 NA -0.31 -4.86 -0.4 3.49e-6 Obesity-related traits; TGCT cis rs6892003 0.951 rs1507805 chr5:174193309 C/T cg06056415 chr5:174162510 NA -0.41 -4.66 -0.39 7.99e-6 Clopidogrel active metabolite levels; TGCT cis rs2799081 1 rs2799081 chr6:28270584 T/C cg11262757 chr6:27280423 POM121L2 0.52 5.12 0.42 1.14e-6 Myopia; TGCT cis rs1023500 0.596 rs5751204 chr22:42433801 C/T cg05082376 chr22:42548792 NA -0.22 -5.3 -0.43 5.09e-7 Schizophrenia; TGCT cis rs6840360 0.571 rs11944139 chr4:152505291 T/C cg17479576 chr4:152424074 FAM160A1 -0.72 -7.81 -0.57 2.09e-12 Intelligence (multi-trait analysis); TGCT trans rs7824557 0.564 rs2736290 chr8:11234298 C/T cg15556689 chr8:8085844 FLJ10661 -0.74 -6.68 -0.51 7.04e-10 Retinal vascular caliber; TGCT cis rs9807989 0.839 rs1974675 chr2:102986375 G/A cg09003973 chr2:102972529 NA 0.66 5.81 0.46 4.92e-8 Asthma; TGCT cis rs1062177 1.000 rs2915877 chr5:151150601 C/G cg00977110 chr5:151150581 G3BP1 0.4 4.57 0.38 1.16e-5 Preschool internalizing problems; TGCT cis rs72781680 0.898 rs72788218 chr2:24090435 C/T cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs10174077 0.874 rs11892439 chr2:152469858 T/A cg19508488 chr2:152266495 RIF1 0.7 6.66 0.51 7.93e-10 Squamous cell lung carcinoma; TGCT cis rs6964587 1.000 rs11772102 chr7:91558326 A/T cg17063962 chr7:91808500 NA -0.9 -9.67 -0.66 7.91e-17 Breast cancer; TGCT trans rs10022799 0.725 rs7658246 chr4:168135377 A/T cg08507725 chr4:8239220 SH3TC1 0.39 7.34 0.55 2.4e-11 Cognitive function; TGCT cis rs9549367 0.789 rs2316442 chr13:113877487 C/T cg18105134 chr13:113819100 PROZ -0.33 -5.34 -0.43 4.25e-7 Platelet distribution width; TGCT trans rs2760061 0.819 rs708111 chr1:228191365 G/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.24 -0.55 4.17e-11 Diastolic blood pressure; TGCT cis rs2795502 0.872 rs2744062 chr10:43254789 T/A cg20628663 chr10:43360327 NA -0.43 -5.05 -0.41 1.51e-6 Blood protein levels; TGCT cis rs2243480 1.000 rs1499613 chr7:65730860 G/A cg07424592 chr7:64974309 NA -1.32 -7.74 -0.57 3e-12 Diabetic kidney disease; TGCT cis rs3784262 0.565 rs4646605 chr15:58287912 C/A cg12031962 chr15:58353849 ALDH1A2 0.37 5.24 0.43 6.8e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs11098499 0.754 rs12509621 chr4:120249660 T/C cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs7647973 0.626 rs35129566 chr3:49866584 T/G cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.83 -0.4 3.96e-6 Menarche (age at onset); TGCT cis rs6450176 0.909 rs3776712 chr5:53304179 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs7666738 0.546 rs34159897 chr4:98787367 T/C cg18180107 chr4:99064573 C4orf37 0.52 4.58 0.38 1.13e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs68170813 0.559 rs6949961 chr7:106850755 G/T cg02696742 chr7:106810147 HBP1 0.71 5.83 0.46 4.6e-8 Coronary artery disease; TGCT cis rs17376456 0.877 rs34595581 chr5:93369422 G/A cg21475434 chr5:93447410 FAM172A 0.59 4.66 0.39 8.09e-6 Diabetic retinopathy; TGCT cis rs12580194 1.000 rs12580194 chr12:55696558 A/G cg20672549 chr12:56432144 IKZF4 -0.27 -4.76 -0.39 5.35e-6 Cancer; TGCT cis rs71597109 0.608 rs11931087 chr4:102727619 A/G cg14855874 chr4:102712397 BANK1 0.41 4.7 0.39 6.66e-6 Chronic lymphocytic leukemia; TGCT cis rs1023500 0.573 rs2413666 chr22:42459622 C/T cg15557168 chr22:42548783 NA -0.22 -5.49 -0.44 2.17e-7 Schizophrenia; TGCT cis rs7312933 0.533 rs17551006 chr12:42848738 G/C cg19980929 chr12:42632907 YAF2 0.43 6.1 0.48 1.26e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9814567 1.000 rs9814567 chr3:134218557 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 0.99 10.0 0.67 1.28e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4665809 1.000 rs4665816 chr2:26305094 G/C cg22920501 chr2:26401640 FAM59B -0.73 -6.28 -0.49 5.18e-9 Gut microbiome composition (summer); TGCT cis rs801193 0.569 rs881285 chr7:66119420 A/G cg11764359 chr7:65958608 NA -0.55 -4.87 -0.4 3.3e-6 Aortic root size; TGCT cis rs7618915 0.547 rs33967311 chr3:52683864 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.6 5.84 0.46 4.26e-8 Bipolar disorder; TGCT cis rs1519814 0.581 rs1879150 chr8:121011233 A/T cg22335954 chr8:121166405 COL14A1 -0.36 -4.52 -0.38 1.44e-5 Breast cancer; TGCT cis rs7954584 0.710 rs10840641 chr12:122465831 G/T cg21016266 chr12:122356598 WDR66 0.41 4.96 0.41 2.32e-6 Mean corpuscular volume; TGCT cis rs7666738 0.791 rs7665273 chr4:98997413 C/A cg18180107 chr4:99064573 C4orf37 0.53 4.84 0.4 3.72e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7662987 0.517 rs2602845 chr4:100023944 T/C cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Smoking initiation; TGCT cis rs225245 0.791 rs3890901 chr17:34011322 A/C cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs9303401 1.000 rs6503882 chr17:56915761 T/C cg12560992 chr17:57184187 TRIM37 0.54 5.68 0.45 9.06e-8 Cognitive test performance; TGCT cis rs13323323 1.000 rs13323323 chr3:44333324 G/T cg04389838 chr3:44770851 ZNF501 -0.42 -4.73 -0.39 5.94e-6 IgG glycosylation; TGCT cis rs6988636 0.710 rs17315999 chr8:124153763 A/G cg27053337 chr8:124217698 FAM83A 0.72 5.08 0.42 1.34e-6 Urinary uromodulin levels; TGCT cis rs9322193 0.884 rs9322210 chr6:150016576 G/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs514406 0.929 rs557847 chr1:53333116 A/G cg25767906 chr1:53392781 SCP2 -0.56 -6.55 -0.51 1.41e-9 Monocyte count; TGCT trans rs1005277 0.563 rs2505215 chr10:38481273 A/G cg27523141 chr10:43048294 ZNF37B 0.73 8.51 0.61 4.68e-14 Extrinsic epigenetic age acceleration; TGCT cis rs10838634 1.000 rs73456126 chr11:46814785 A/G cg18332754 chr11:46939436 LRP4 0.9 4.59 0.38 1.05e-5 Schizophrenia; TGCT cis rs9486719 0.656 rs6924957 chr6:96853579 G/T cg18709589 chr6:96969512 KIAA0776 0.64 4.52 0.38 1.41e-5 Migraine;Coronary artery disease; TGCT cis rs2836974 0.932 rs13048178 chr21:40561012 G/T cg11890956 chr21:40555474 PSMG1 1.1 12.36 0.74 2.27e-23 Cognitive function; TGCT cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg03806693 chr22:41940476 POLR3H -1.14 -13.51 -0.77 4e-26 Vitiligo; TGCT cis rs10504229 1.000 rs73609764 chr8:58192971 G/A cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs8177253 0.665 rs12493887 chr3:133440737 T/C cg08048268 chr3:133502702 NA -0.54 -7.2 -0.54 5.06e-11 Iron status biomarkers; TGCT trans rs12655019 0.920 rs74865790 chr5:56219698 T/C cg25190722 chr1:3801660 DFFB 0.65 7.42 0.55 1.63e-11 Breast cancer (early onset); TGCT cis rs7618915 1.000 rs3844291 chr3:52341215 A/C cg07507251 chr3:52567010 NT5DC2 0.47 6.15 0.48 9.57e-9 Bipolar disorder; TGCT cis rs7811142 0.943 rs67483801 chr7:100031758 G/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs2836950 0.565 rs2150413 chr21:40614878 C/T cg06238570 chr21:40685208 BRWD1 -0.6 -6.27 -0.49 5.47e-9 Menarche (age at onset); TGCT cis rs2464469 0.654 rs2067062 chr15:58341954 T/G cg12031962 chr15:58353849 ALDH1A2 -0.4 -5.88 -0.47 3.57e-8 Barrett's esophagus or Esophageal adenocarcinoma; TGCT cis rs5167 0.533 rs55778858 chr19:45485465 G/A cg13119609 chr19:45449297 APOC2 0.23 4.65 0.39 8.26e-6 Blood protein levels; TGCT cis rs6088580 0.634 rs6059890 chr20:33101653 G/C cg06115741 chr20:33292138 TP53INP2 0.54 4.63 0.38 9.06e-6 Glomerular filtration rate (creatinine); TGCT cis rs4689592 0.554 rs3951346 chr4:7073321 C/T cg02503808 chr4:7069936 GRPEL1 1.0 9.66 0.66 8.38e-17 Monocyte percentage of white cells; TGCT cis rs597539 0.652 rs584108 chr11:68630282 A/T cg21862992 chr11:68658383 NA -0.43 -5.99 -0.47 2.15e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7824557 0.767 rs3808509 chr8:11163256 G/T cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs1552244 0.572 rs59132826 chr3:10169725 G/A cg00149659 chr3:10157352 C3orf10 1.18 7.44 0.56 1.44e-11 Alzheimer's disease; TGCT cis rs17152411 0.895 rs7079153 chr10:126587146 C/G cg07906193 chr10:126599966 NA 0.41 5.05 0.41 1.52e-6 Height; TGCT cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg22105103 chr4:187893119 NA 0.33 4.56 0.38 1.19e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9322193 0.923 rs10782311 chr6:149943728 A/G cg13206674 chr6:150067644 NUP43 0.52 4.46 0.37 1.78e-5 Lung cancer; TGCT cis rs2739330 0.892 rs5751776 chr22:24266954 A/C cg01585852 chr22:24235823 MIF -0.22 -4.82 -0.4 4.2e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9467711 0.790 rs13220495 chr6:26441640 C/T cg16898833 chr6:26189333 HIST1H4D 1.37 6.2 0.49 7.83e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs9291683 0.530 rs10939620 chr4:9946132 C/T cg00071950 chr4:10020882 SLC2A9 -0.64 -8.25 -0.6 2.01e-13 Bone mineral density; TGCT cis rs9894429 0.646 rs7406522 chr17:79615396 G/T cg21028142 chr17:79581711 NPLOC4 0.28 5.87 0.47 3.73e-8 Eye color traits; TGCT cis rs3845702 0.733 rs12693217 chr2:180841914 T/G cg01881094 chr2:180872142 CWC22 -1.03 -6.51 -0.5 1.72e-9 Schizophrenia; TGCT cis rs9354352 0.967 rs9354351 chr6:66696271 G/A cg07460842 chr6:66804631 NA 0.65 6.68 0.51 7.29e-10 Initial pursuit acceleration in psychotic disorders; TGCT cis rs7193541 0.508 rs7188581 chr16:74672901 T/A cg01733217 chr16:74700730 RFWD3 1.01 13.21 0.76 2.1e-25 Multiple myeloma; TGCT cis rs9322193 0.884 rs9480009 chr6:150079638 A/G cg13206674 chr6:150067644 NUP43 0.53 4.65 0.39 8.3e-6 Lung cancer; TGCT cis rs11190604 1.000 rs10883511 chr10:102299407 A/G cg16342193 chr10:102329863 NA -0.41 -5.12 -0.42 1.15e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11098499 0.954 rs4577559 chr4:120404043 T/G cg09307838 chr4:120376055 NA 0.69 6.64 0.51 8.97e-10 Corneal astigmatism; TGCT cis rs7255045 0.788 rs4804737 chr19:12947938 C/T cg23899408 chr19:12877188 HOOK2 0.54 4.47 0.37 1.75e-5 Mean corpuscular volume; TGCT cis rs727505 0.954 rs1525613 chr7:124658636 A/G cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs4325129 0.651 rs4656837 chr1:159505297 C/T cg07417683 chr1:159440267 NA 0.37 4.52 0.38 1.4e-5 Obesity-related traits; TGCT cis rs7829975 0.560 rs56094035 chr8:8551622 G/A cg17143192 chr8:8559678 CLDN23 -0.49 -4.94 -0.41 2.44e-6 Mood instability; TGCT cis rs9902453 0.845 rs58606097 chr17:28020379 G/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.27 0.55 3.55e-11 Coffee consumption (cups per day); TGCT cis rs9915657 0.743 rs9894720 chr17:70097607 C/T cg06234051 chr17:70120541 SOX9 -0.23 -4.93 -0.4 2.63e-6 Thyroid hormone levels; TGCT cis rs921968 0.643 rs4674319 chr2:219510320 C/T cg02176678 chr2:219576539 TTLL4 0.37 5.29 0.43 5.24e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs1348850 0.519 rs13034781 chr2:178523550 C/A cg22681709 chr2:178499509 PDE11A -0.48 -6.08 -0.48 1.36e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs12479064 0.694 rs11896520 chr2:99995517 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.71 -5.81 -0.46 5.01e-8 Chronic sinus infection; TGCT cis rs6952808 0.689 rs2008263 chr7:2048335 A/G cg22963979 chr7:1858916 MAD1L1 -0.44 -6.93 -0.53 2.01e-10 Bipolar disorder and schizophrenia; TGCT cis rs10256972 0.514 rs2140578 chr7:1214003 T/C cg09177884 chr7:1199841 ZFAND2A -0.64 -6.35 -0.5 3.64e-9 Longevity;Endometriosis; TGCT cis rs4824093 0.610 rs2208023 chr22:50249983 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.12 -6.87 -0.52 2.83e-10 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1670533 1.000 rs6839931 chr4:1053172 A/G cg27284194 chr4:1044797 NA 0.67 5.77 0.46 5.9e-8 Recombination rate (females); TGCT cis rs9611565 0.546 rs5758426 chr22:42098763 T/G cg03806693 chr22:41940476 POLR3H 1.0 10.29 0.68 2.52e-18 Vitiligo; TGCT cis rs3733585 0.648 rs35954357 chr4:9978758 G/C cg11266682 chr4:10021025 SLC2A9 0.59 7.62 0.56 5.7e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7085104 0.552 rs11191414 chr10:104601565 A/T cg04362960 chr10:104952993 NT5C2 0.56 4.92 0.4 2.68e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7959452 0.503 rs7300266 chr12:69654187 A/G cg11871910 chr12:69753446 YEATS4 0.62 6.22 0.49 6.95e-9 Blood protein levels; TGCT cis rs10514758 0.744 rs72947739 chr3:114909861 G/T cg05943254 chr3:114009756 NA -0.76 -4.53 -0.38 1.39e-5 Urate levels in obese individuals; TGCT cis rs11792861 0.888 rs57314245 chr9:111813832 G/A cg14432460 chr9:111696404 IKBKAP;C9orf6 0.47 4.6 0.38 1.03e-5 Menarche (age at onset); TGCT cis rs61884328 0.733 rs61897853 chr11:47217906 C/T cg13308137 chr11:47528955 CUGBP1 0.38 4.48 0.37 1.65e-5 Total body bone mineral density (age over 60); TGCT cis rs1670533 1.000 rs6812596 chr4:1069866 A/G cg20887711 chr4:1340912 KIAA1530 0.69 5.5 0.44 2.03e-7 Recombination rate (females); TGCT cis rs902774 0.554 rs4503623 chr12:53353759 T/C cg25025879 chr12:53359317 NA -0.44 -4.83 -0.4 3.97e-6 Prostate cancer; TGCT cis rs797680 0.856 rs6685271 chr1:93634590 C/A cg17826107 chr1:92977322 EVI5 -0.23 -5.0 -0.41 1.88e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs2645424 0.550 rs12338 chr8:11710888 G/C cg18999641 chr8:11876646 NA 0.23 5.03 0.41 1.7e-6 Non-alcoholic fatty liver disease histology (other);Non-alcoholic fatty liver disease histology (lobular); TGCT cis rs7027203 0.576 rs11792101 chr9:96535470 C/T cg14598338 chr9:96623480 NA 0.51 7.4 0.55 1.83e-11 DNA methylation (variation); TGCT cis rs1218582 0.772 rs10908445 chr1:154849590 A/G cg24250549 chr1:154909240 PMVK -0.6 -6.35 -0.5 3.68e-9 Prostate cancer; TGCT cis rs7172809 0.643 rs75159723 chr15:77841841 A/G cg22256960 chr15:77711686 NA -0.48 -4.84 -0.4 3.84e-6 Glucose homeostasis traits; TGCT cis rs4665809 0.627 rs1465720 chr2:26412638 G/T cg04944784 chr2:26401820 FAM59B -0.8 -6.84 -0.52 3.27e-10 Gut microbiome composition (summer); TGCT cis rs7584330 0.910 rs72620830 chr2:238396985 C/T cg14458575 chr2:238380390 NA 0.5 7.15 0.54 6.63e-11 Prostate cancer; TGCT cis rs28830936 0.510 rs11858843 chr15:42092915 C/A cg17847044 chr15:42102381 MAPKBP1 -0.18 -5.14 -0.42 1.03e-6 Diastolic blood pressure; TGCT cis rs13108904 0.840 rs3915420 chr4:1260337 T/C cg05665937 chr4:1216051 CTBP1 0.24 4.65 0.39 8.32e-6 Obesity-related traits; TGCT cis rs11997175 0.574 rs4364597 chr8:33653729 G/C ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs9921338 0.961 rs9936328 chr16:11438221 T/A cg00044050 chr16:11439710 C16orf75 -0.91 -7.11 -0.54 8.19e-11 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs67311347 1.000 rs73076035 chr3:40439881 G/C cg17264618 chr3:40429014 ENTPD3 0.32 4.57 0.38 1.18e-5 Renal cell carcinoma; TGCT cis rs10504229 1.000 rs58947041 chr8:58188934 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs4794202 0.534 rs9915028 chr17:45927491 G/T cg02219949 chr17:45927392 SP6 0.38 4.55 0.38 1.24e-5 Alzheimer's disease (cognitive decline); TGCT cis rs295140 1.000 rs295140 chr2:201160699 T/C cg04283868 chr2:201171347 SPATS2L -0.63 -6.28 -0.49 5.19e-9 QT interval; TGCT cis rs7923452 0.938 rs34930615 chr10:30761051 G/A cg18806716 chr10:30721971 MAP3K8 0.66 6.06 0.48 1.48e-8 Itch intensity from mosquito bite; TGCT cis rs10504229 0.861 rs57314710 chr8:58196051 T/C cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs28386778 0.897 rs2854214 chr17:61945449 C/G cg06873352 chr17:61820015 STRADA -0.55 -6.07 -0.48 1.43e-8 Prudent dietary pattern; TGCT cis rs17122693 0.748 rs17122714 chr14:51104741 C/T cg04730355 chr14:51134070 SAV1 1.34 12.06 0.73 1.24e-22 Cognitive performance; TGCT cis rs245880 0.666 rs245894 chr7:29192686 G/C cg17163760 chr7:29186267 CPVL -0.41 -5.21 -0.42 7.51e-7 Warfarin maintenance dose; TGCT cis rs4563143 0.663 rs5025682 chr19:29238670 A/C cg04546413 chr19:29218101 NA 0.73 6.49 0.5 1.87e-9 Methadone dose in opioid dependence; TGCT cis rs8180040 0.966 rs11707895 chr3:47574937 G/A cg27129171 chr3:47204927 SETD2 -0.64 -7.34 -0.55 2.41e-11 Colorectal cancer; TGCT cis rs262150 0.625 rs117651953 chr7:158780563 G/A cg01219135 chr7:158766336 NA -0.46 -4.72 -0.39 6.19e-6 Facial morphology (factor 20); TGCT cis rs3733585 0.664 rs17185870 chr4:9958214 C/A cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.71e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs2204008 0.754 rs11181244 chr12:38302454 T/C cg26384229 chr12:38710491 ALG10B 0.82 7.14 0.54 6.78e-11 Bladder cancer; TGCT cis rs4819052 0.851 rs9979545 chr21:46679805 G/A cg06618935 chr21:46677482 NA -0.37 -5.56 -0.45 1.58e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs28595532 0.920 rs114462478 chr4:119752656 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs8072100 0.754 rs8081717 chr17:45653921 T/A cg08085267 chr17:45401833 C17orf57 0.47 5.13 0.42 1.07e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7954584 0.567 rs11043243 chr12:122356370 G/C cg22618164 chr12:122356400 WDR66 0.69 6.52 0.51 1.6e-9 Mean corpuscular volume; TGCT cis rs3784262 0.669 rs34226780 chr15:58280168 G/A cg12031962 chr15:58353849 ALDH1A2 -0.41 -5.95 -0.47 2.53e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9399137 0.507 rs11759062 chr6:135381248 A/C cg24558204 chr6:135376177 HBS1L 0.47 4.73 0.39 5.98e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs832540 0.898 rs331497 chr5:56251660 G/T cg12311346 chr5:56204834 C5orf35 0.44 4.87 0.4 3.38e-6 Coronary artery disease; TGCT cis rs477895 0.568 rs12418035 chr11:63871558 G/A cg23719950 chr11:63933701 MACROD1 -0.61 -5.24 -0.43 6.61e-7 Mean platelet volume; TGCT cis rs7772486 0.686 rs1292337 chr6:145967807 A/G cg13319975 chr6:146136371 FBXO30 0.5 4.6 0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs2739330 0.576 rs2858912 chr22:24297197 A/G cg11905131 chr22:24372483 LOC391322 -0.98 -12.41 -0.74 1.79e-23 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9914988 0.565 rs34039488 chr17:27320232 G/A cg17523868 chr17:27313033 SEZ6 -0.56 -4.77 -0.39 5.17e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs11190604 0.943 rs3750631 chr10:102279294 A/G cg16342193 chr10:102329863 NA -0.42 -5.37 -0.43 3.74e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs514406 0.708 rs514881 chr1:53336737 A/G cg22166914 chr1:53195759 ZYG11B -0.32 -5.22 -0.42 7.31e-7 Monocyte count; TGCT cis rs826838 0.935 rs11169547 chr12:39185625 C/A cg26384229 chr12:38710491 ALG10B 0.98 8.78 0.62 1.07e-14 Heart rate; TGCT cis rs1801251 1.000 rs12987513 chr2:233622066 A/G cg25237894 chr2:233734115 C2orf82 0.31 5.62 0.45 1.21e-7 Coronary artery disease; TGCT cis rs7772486 0.790 rs2253654 chr6:146199445 T/C cg13319975 chr6:146136371 FBXO30 -0.54 -4.81 -0.4 4.35e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs5760092 0.842 rs5751763 chr22:24247793 T/C cg12419862 chr22:24373484 LOC391322 -0.8 -6.62 -0.51 9.91e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs9303542 0.559 rs12947405 chr17:46614755 C/T cg25032089 chr17:46643351 HOXB3 0.58 5.47 0.44 2.38e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs2629540 0.855 rs12776722 chr10:126469833 G/A cg08799069 chr10:126477246 METTL10 0.31 4.59 0.38 1.06e-5 Cocaine dependence; TGCT cis rs7937612 1.000 rs7117321 chr11:120239051 T/C cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.7 -0.39 6.76e-6 Intraocular pressure; TGCT cis rs7552404 0.727 rs7547508 chr1:76327958 A/G cg22875332 chr1:76189707 ACADM -0.57 -6.14 -0.48 1.05e-8 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7843479 0.544 rs7839925 chr8:21792983 G/C cg17168535 chr8:21777572 XPO7 0.91 9.55 0.65 1.53e-16 Mean corpuscular volume; TGCT cis rs35160687 0.798 rs6547674 chr2:86552919 G/T cg03171300 chr2:86307199 POLR1A -0.27 -4.59 -0.38 1.07e-5 Night sleep phenotypes; TGCT cis rs7829975 0.667 rs1877119 chr8:8707197 C/G cg15556689 chr8:8085844 FLJ10661 0.69 6.21 0.49 7.27e-9 Mood instability; TGCT cis rs74544699 1.000 rs11574450 chr4:74847111 A/C cg15398841 chr4:74847761 PF4 0.88 4.87 0.4 3.3e-6 Growth-regulated protein alpha levels; TGCT cis rs79349575 0.783 rs62075852 chr17:47017176 T/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs72634258 0.554 rs17374781 chr1:7919363 A/G cg26816564 chr1:7831052 VAMP3 -0.64 -5.2 -0.42 7.82e-7 Inflammatory bowel disease; TGCT cis rs6089829 0.962 rs1060490 chr20:61665871 A/G cg08564027 chr20:61660810 NA 0.37 6.85 0.52 3.1e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9372498 0.505 rs9481811 chr6:118801174 T/C cg21191810 chr6:118973309 C6orf204 -0.36 -4.74 -0.39 5.8e-6 Diastolic blood pressure; TGCT cis rs2797160 0.651 rs9491503 chr6:126031682 G/A cg05901451 chr6:126070800 HEY2 0.75 6.67 0.51 7.42e-10 Endometrial cancer; TGCT cis rs67311347 1.000 rs4973994 chr3:40453024 T/C cg13683864 chr3:40499215 RPL14 -1.18 -13.68 -0.78 1.54e-26 Renal cell carcinoma; TGCT cis rs17270561 0.723 rs12213243 chr6:25890108 C/T cg16482183 chr6:26056742 HIST1H1C 0.9 6.76 0.52 4.9e-10 Iron status biomarkers; TGCT cis rs8056742 1.000 rs16975170 chr16:85092575 C/T cg00229868 chr16:85520891 NA 0.28 4.67 0.39 7.57e-6 Amyotrophic lateral sclerosis; TGCT cis rs1862618 0.853 rs866222 chr5:56184444 T/C cg24531977 chr5:56204891 C5orf35 -0.76 -7.34 -0.55 2.45e-11 Initial pursuit acceleration; TGCT cis rs7586879 0.639 rs4077678 chr2:25122840 C/G cg01884057 chr2:25150051 NA 0.35 6.9 0.53 2.39e-10 Body mass index; TGCT trans rs7819412 0.537 rs2127127 chr8:11434792 C/G cg15556689 chr8:8085844 FLJ10661 -0.75 -7.08 -0.54 9.37e-11 Triglycerides; TGCT cis rs986417 1.000 rs1955699 chr14:61045989 A/G cg27398547 chr14:60952738 C14orf39 1.49 8.69 0.62 1.81e-14 Gut microbiota (bacterial taxa); TGCT cis rs259282 0.560 rs4805786 chr19:33120265 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.59 5.48 0.44 2.25e-7 Schizophrenia; TGCT cis rs9325144 0.723 rs3887436 chr12:39189526 A/C cg26384229 chr12:38710491 ALG10B -0.61 -5.67 -0.45 9.5e-8 Morning vs. evening chronotype; TGCT cis rs9549367 0.789 rs2287253 chr13:113891075 G/A cg00898013 chr13:113819073 PROZ 0.43 5.21 0.42 7.53e-7 Platelet distribution width; TGCT cis rs67073037 0.955 rs4666141 chr2:29164022 G/T cg09522027 chr2:28974177 PPP1CB 0.57 4.49 0.37 1.59e-5 Breast cancer;Breast cancer (estrogen-receptor negative); TGCT cis rs394563 0.589 rs1900300 chr6:149641627 T/C cg11245181 chr6:149772854 ZC3H12D 0.27 4.44 0.37 1.94e-5 Dupuytren's disease; TGCT cis rs6570726 0.935 rs367643 chr6:145859602 A/C cg05347473 chr6:146136440 FBXO30 0.49 4.54 0.38 1.29e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs6700896 0.500 rs11208687 chr1:66076358 C/T cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs769267 0.930 rs3794993 chr19:19611550 G/T cg03709012 chr19:19516395 GATAD2A 0.74 6.09 0.48 1.28e-8 Tonsillectomy; TGCT cis rs10504229 0.906 rs73607869 chr8:58172665 G/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.920 rs115500312 chr4:119752551 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs6545883 0.868 rs7574631 chr2:61825142 T/G cg15711740 chr2:61764176 XPO1 -0.59 -5.64 -0.45 1.08e-7 Tuberculosis; TGCT cis rs7617773 0.817 rs79310258 chr3:48259667 C/G cg11946769 chr3:48343235 NME6 0.76 6.67 0.51 7.6e-10 Coronary artery disease; TGCT cis rs896854 0.684 rs10098778 chr8:95992020 C/T cg16049864 chr8:95962084 TP53INP1 -0.69 -9.84 -0.66 3.17e-17 Type 2 diabetes; TGCT cis rs9486715 0.867 rs4131519 chr6:96964939 G/A cg18709589 chr6:96969512 KIAA0776 0.79 7.53 0.56 8.99e-12 Headache; TGCT cis rs2282802 0.635 rs269767 chr5:139536922 A/G cg01081189 chr5:139537190 NA 0.3 5.62 0.45 1.2e-7 Intelligence (multi-trait analysis); TGCT cis rs362272 0.545 rs3135146 chr4:3307638 C/G cg18352616 chr4:3374830 RGS12 -0.25 -5.03 -0.41 1.71e-6 Serum sulfate level; TGCT cis rs1799949 1.000 rs8176318 chr17:41197274 G/T cg19454999 chr17:41278357 BRCA1;NBR2 0.48 4.88 0.4 3.21e-6 Menopause (age at onset); TGCT cis rs644799 0.710 rs12272061 chr11:95524067 G/T cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.5 0.61 5.03e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs17030434 0.834 rs1456399 chr4:154735242 C/T cg14289246 chr4:154710475 SFRP2 -0.92 -7.65 -0.57 4.85e-12 Electrocardiographic conduction measures; TGCT cis rs7552404 0.961 rs1061337 chr1:76227022 A/G cg10523679 chr1:76189770 ACADM 0.91 9.53 0.65 1.77e-16 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7666738 0.800 rs7683737 chr4:99070880 A/T cg17366294 chr4:99064904 C4orf37 0.73 7.45 0.56 1.4e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10504229 1.000 rs76023408 chr8:58193345 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs2637266 0.846 rs752006 chr10:78393136 G/T cg18941641 chr10:78392320 NA 0.43 5.58 0.45 1.46e-7 Pulmonary function; TGCT cis rs453301 0.658 rs13271797 chr8:8885954 G/A cg00184457 chr8:8946301 NA -0.27 -4.85 -0.4 3.69e-6 Joint mobility (Beighton score); TGCT cis rs2933343 1.000 rs1680790 chr3:128625853 G/T cg11901034 chr3:128598214 ACAD9 -0.63 -5.13 -0.42 1.08e-6 IgG glycosylation; TGCT cis rs7208859 0.623 rs1054397 chr17:29110196 T/C cg13385521 chr17:29058706 SUZ12P 0.79 4.74 0.39 5.7e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs2980439 0.818 rs2945249 chr8:8094726 G/A cg06636001 chr8:8085503 FLJ10661 0.85 8.73 0.62 1.47e-14 Neuroticism; TGCT cis rs10832963 0.847 rs4237722 chr11:18639363 T/C cg20219074 chr11:18656078 SPTY2D1 0.95 9.01 0.63 3.04e-15 Breast cancer; TGCT cis rs1218582 0.772 rs2061690 chr1:154919080 C/T cg16680214 chr1:154839983 KCNN3 -0.37 -7.82 -0.57 2e-12 Prostate cancer; TGCT cis rs7611238 0.583 rs9288744 chr3:195058837 C/T cg27323046 chr3:195102265 ACAP2 -0.32 -4.5 -0.37 1.55e-5 Body mass index; TGCT cis rs892961 0.932 rs6501954 chr17:75414398 G/C cg05865280 chr17:75406074 SEPT9 0.28 6.71 0.52 6.16e-10 Airflow obstruction; TGCT cis rs57221529 0.709 rs111352378 chr5:577079 G/A cg09021430 chr5:549028 NA -0.37 -5.16 -0.42 9.7e-7 Lung disease severity in cystic fibrosis; TGCT cis rs12142240 0.667 rs41293287 chr1:46808852 C/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT trans rs877282 1.000 rs12219807 chr10:772870 A/C cg22713356 chr15:30763199 NA 1.16 10.02 0.67 1.16e-17 Uric acid levels; TGCT cis rs10779751 1.000 rs2300094 chr1:11266044 C/T cg08854313 chr1:11322531 MTOR 0.92 10.28 0.68 2.6e-18 Body mass index; TGCT cis rs11190604 1.000 rs2489048 chr10:102348497 G/T cg16342193 chr10:102329863 NA -0.43 -5.43 -0.44 2.79e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7945705 1.000 rs11603841 chr11:8834680 T/C cg21881798 chr11:8931708 C11orf17;ST5 0.41 4.46 0.37 1.85e-5 Hemoglobin concentration; TGCT cis rs763014 0.865 rs710924 chr16:633353 T/C cg09263875 chr16:632152 PIGQ 0.3 6.35 0.5 3.63e-9 Height; TGCT cis rs344364 0.518 rs1657129 chr16:1945826 G/A cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs6952808 0.609 rs12699453 chr7:1953056 C/T cg22963979 chr7:1858916 MAD1L1 -0.39 -5.94 -0.47 2.68e-8 Bipolar disorder and schizophrenia; TGCT cis rs1018836 0.632 rs1028255 chr8:91485578 A/T cg16814680 chr8:91681699 NA -0.79 -8.2 -0.59 2.57e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs854765 0.583 rs8070128 chr17:17804725 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.75 -8.0 -0.58 7.59e-13 Total body bone mineral density; TGCT cis rs939658 0.805 rs11638004 chr15:79425765 A/C cg17916960 chr15:79447300 NA -0.49 -7.59 -0.56 6.76e-12 Refractive error; TGCT cis rs9902453 0.765 rs2617883 chr17:28120488 G/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.84 -8.19 -0.59 2.73e-13 Coffee consumption (cups per day); TGCT cis rs7666738 0.830 rs13147195 chr4:98893334 G/T cg17366294 chr4:99064904 C4orf37 0.68 6.87 0.53 2.72e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7584330 0.868 rs7571898 chr2:238383028 T/C cg14458575 chr2:238380390 NA 0.5 7.89 0.58 1.35e-12 Prostate cancer; TGCT cis rs28595532 0.920 rs114792862 chr4:119759938 G/A cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs2594989 0.779 rs2437686 chr3:11588989 C/T cg00170343 chr3:11313890 ATG7 0.65 4.93 0.4 2.61e-6 Circulating chemerin levels; TGCT cis rs1018836 0.884 rs9643307 chr8:91625257 A/C cg16814680 chr8:91681699 NA -0.85 -9.22 -0.64 9.9e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs1670533 0.932 rs4690214 chr4:1054636 T/C cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs911555 0.755 rs35233301 chr14:103885291 A/G cg23461800 chr14:103021989 NA -0.34 -4.58 -0.38 1.1e-5 Intelligence (multi-trait analysis); TGCT cis rs2730245 1.000 rs2730245 chr7:158724789 G/C cg11984989 chr7:158649758 WDR60 -0.95 -8.47 -0.61 5.89e-14 Height; TGCT cis rs9309473 0.606 rs1589576 chr2:73738804 A/G cg07208825 chr2:73871855 ALMS1P 0.24 4.46 0.37 1.83e-5 Metabolite levels; TGCT cis rs2832077 0.527 rs2142375 chr21:30223742 G/A cg24692254 chr21:30365293 RNF160 -0.59 -5.05 -0.41 1.53e-6 Cognitive test performance; TGCT cis rs12257961 0.521 rs10796281 chr10:15375605 T/G cg10616319 chr10:15468812 NA -0.25 -4.56 -0.38 1.2e-5 Selective IgA deficiency; TGCT cis rs28386778 0.897 rs4968662 chr17:61834537 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.96 -0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs910316 1.000 rs9805979 chr14:75566209 G/A cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs28386778 0.901 rs2854194 chr17:61952110 T/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.74 -0.39 5.77e-6 Prudent dietary pattern; TGCT cis rs11585357 0.895 rs4625336 chr1:17630964 G/T cg08277548 chr1:17600880 PADI3 -0.95 -9.47 -0.65 2.45e-16 Hair shape; TGCT trans rs12339966 0.615 rs62529420 chr9:11336775 C/T cg03488587 chr11:64876988 C11orf2 0.32 7.0 0.53 1.42e-10 Systolic blood pressure; TGCT cis rs3796352 1.000 rs34979715 chr3:53048960 G/A cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs35306767 0.903 rs12778891 chr10:950130 T/A cg20503657 chr10:835505 NA 0.75 10.4 0.68 1.37e-18 Eosinophil percentage of granulocytes; TGCT cis rs2072499 0.966 rs6427304 chr1:156156789 A/G cg25208724 chr1:156163844 SLC25A44 1.11 15.72 0.82 2.62e-31 Testicular germ cell tumor; TGCT cis rs9325144 0.723 rs11169535 chr12:39183494 C/T cg10518543 chr12:38710700 ALG10B -0.5 -4.65 -0.39 8.28e-6 Morning vs. evening chronotype; TGCT cis rs1008375 0.966 rs2315645 chr4:17579678 G/C cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6912958 0.559 rs6921504 chr6:88058972 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.68 6.88 0.53 2.68e-10 Monocyte percentage of white cells; TGCT cis rs6540559 0.673 rs17015183 chr1:209948711 A/C cg21951975 chr1:209979733 IRF6 0.69 5.38 0.43 3.58e-7 Cleft lip with or without cleft palate; TGCT cis rs6450176 1.000 rs3776703 chr5:53305259 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs6733011 0.560 rs7579189 chr2:99464718 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.48 -4.78 -0.39 4.78e-6 Bipolar disorder; TGCT cis rs13008689 0.905 rs6752907 chr2:8522010 A/C cg21129864 chr2:9369739 ASAP2 -0.18 -4.46 -0.37 1.8e-5 Longevity; TGCT cis rs12908161 0.959 rs17534709 chr15:85314397 G/C cg12863693 chr15:85201151 NMB 0.44 5.2 0.42 7.87e-7 Schizophrenia; TGCT cis rs62244186 0.711 rs6778410 chr3:44743993 C/T cg10263370 chr3:44754102 ZNF502 -0.43 -5.29 -0.43 5.33e-7 Depressive symptoms; TGCT cis rs4409675 0.576 rs6564 chr1:28212975 A/G cg23691781 chr1:28212827 C1orf38 -0.25 -5.23 -0.43 6.9e-7 Corneal astigmatism; TGCT cis rs12701220 0.894 rs12701406 chr7:1050283 G/A cg27454412 chr7:1067447 C7orf50 -0.48 -4.44 -0.37 1.98e-5 Bronchopulmonary dysplasia; TGCT cis rs7647973 1.000 rs9842132 chr3:49427933 G/A cg06212747 chr3:49208901 KLHDC8B -0.59 -4.72 -0.39 6.19e-6 Menarche (age at onset); TGCT trans rs6069325 0.529 rs11905021 chr20:54139226 T/C cg26869512 chr4:8389770 ACOX3 0.47 6.92 0.53 2.12e-10 Motion sickness; TGCT cis rs1372520 0.748 rs990085 chr4:90754771 A/G cg20003494 chr4:90757398 SNCA -0.63 -5.09 -0.42 1.3e-6 Neuroticism; TGCT trans rs57221529 0.766 rs4081847 chr5:574072 C/T cg25482853 chr8:67687455 SGK3 1.19 10.96 0.7 5.68e-20 Lung disease severity in cystic fibrosis; TGCT cis rs1887596 0.705 rs9553874 chr13:27189883 C/T cg01312412 chr13:27282625 NA 0.31 5.52 0.44 1.9e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs3087591 0.960 rs1801052 chr17:29508775 C/T cg24425628 chr17:29625626 OMG;NF1 0.47 7.22 0.54 4.59e-11 Hip circumference; TGCT cis rs13256369 1.000 rs12547721 chr8:8570671 C/T cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT cis rs2816958 0.803 rs2737679 chr1:200088240 T/A cg07971716 chr1:199773294 NA 0.46 4.52 0.38 1.45e-5 Ulcerative colitis;Inflammatory bowel disease; TGCT cis rs7666738 0.830 rs28878289 chr4:98855181 C/T cg17366294 chr4:99064904 C4orf37 0.7 7.27 0.55 3.62e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs12477438 0.501 rs11685756 chr2:99766215 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 16.87 0.83 6.81e-34 Chronic sinus infection; TGCT cis rs2851682 0.706 rs2727271 chr11:61603358 A/T cg19610905 chr11:61596333 FADS2 -0.94 -5.04 -0.41 1.62e-6 Gestational age at birth (child effect);Trans fatty acid levels; TGCT cis rs6500602 0.701 rs1362626 chr16:4549226 C/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.27 4.97 0.41 2.14e-6 Schizophrenia; TGCT cis rs7666738 0.716 rs114187620 chr4:98819534 T/A cg17366294 chr4:99064904 C4orf37 0.7 7.45 0.56 1.42e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs1878931 0.615 rs4786412 chr16:3440390 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 12.26 0.74 3.95e-23 Body mass index (adult); TGCT cis rs4478858 0.684 rs3753374 chr1:31740668 C/T cg00250761 chr1:31883323 NA -0.25 -4.48 -0.37 1.64e-5 Alcohol dependence; TGCT cis rs6570726 0.791 rs383841 chr6:145888329 G/T cg13319975 chr6:146136371 FBXO30 0.51 4.6 0.38 1.01e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs13064411 0.696 rs7619913 chr3:113017503 A/G cg18753928 chr3:113234510 CCDC52 -0.71 -5.09 -0.42 1.29e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs3741404 0.825 rs11603538 chr11:63986713 C/A cg04317338 chr11:64019027 PLCB3 0.51 4.55 0.38 1.27e-5 Platelet count; TGCT trans rs2760061 0.819 rs708112 chr1:228192452 G/A cg16006296 chr10:38738647 LOC399744 -0.31 -7.24 -0.55 4.17e-11 Diastolic blood pressure; TGCT cis rs2177596 0.525 rs2229814 chr2:227954599 G/A cg11843606 chr2:227700838 RHBDD1 -0.55 -5.07 -0.41 1.44e-6 Body mass index; TGCT cis rs17376456 0.825 rs10054903 chr5:93281491 C/A cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs2439831 1.000 rs2245054 chr15:43751909 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.81 5.66 0.45 9.81e-8 Lung cancer in ever smokers; TGCT trans rs2018683 1.000 rs160837 chr7:29012732 C/G cg19402173 chr7:128379420 CALU -0.73 -6.94 -0.53 1.92e-10 Response to irinotecan and platinum-based chemotherapy in non-small-cell lung cancer; TGCT cis rs7772486 0.754 rs702304 chr6:145990797 A/G cg13319975 chr6:146136371 FBXO30 0.56 5.03 0.41 1.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs10504229 0.774 rs72650880 chr8:58164727 C/T cg08280861 chr8:58055591 NA 0.39 4.76 0.39 5.35e-6 Developmental language disorder (linguistic errors); TGCT cis rs3733585 0.673 rs4455410 chr4:9953297 C/T cg00071950 chr4:10020882 SLC2A9 0.53 6.33 0.49 4.11e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs769267 0.930 rs10282 chr19:19619317 T/C cg08509172 chr19:19383838 TM6SF2 -0.34 -4.48 -0.37 1.71e-5 Tonsillectomy; TGCT cis rs10870270 0.500 rs9419217 chr10:133758379 A/G cg03810717 chr10:132909213 TCERG1L 0.32 4.48 0.37 1.67e-5 Amyotrophic lateral sclerosis in C9orf72 mutation positive individuals; TGCT cis rs2997457 1.000 rs2997457 chr1:26343112 A/G cg16724196 chr1:26126450 SEPN1 -0.57 -4.59 -0.38 1.09e-5 Facial morphology (factor 16); TGCT cis rs7192750 0.586 rs8050488 chr16:71911470 C/T cg06353428 chr16:71660113 MARVELD3 0.83 6.97 0.53 1.65e-10 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs17173637 0.614 rs116435075 chr7:150505395 G/A cg06746365 chr7:151468796 PRKAG2 0.28 4.44 0.37 1.93e-5 HDL cholesterol;HDL cholesterol levels; TGCT cis rs7666738 0.830 rs28785514 chr4:98959135 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6430585 0.583 rs79176913 chr2:136638113 C/A cg07169764 chr2:136633963 MCM6 1.23 11.98 0.73 1.9e-22 Corneal structure; TGCT cis rs1887596 0.624 rs9553857 chr13:27136589 C/A cg01312412 chr13:27282625 NA 0.27 4.8 0.4 4.4e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs6545883 0.929 rs6545873 chr2:61733012 T/C cg15711740 chr2:61764176 XPO1 -0.55 -5.01 -0.41 1.85e-6 Tuberculosis; TGCT cis rs796364 0.539 rs6738494 chr2:200697058 A/C cg17644776 chr2:200775616 C2orf69 0.35 4.91 0.4 2.75e-6 Schizophrenia; TGCT cis rs7524258 0.868 rs2157499 chr1:7271472 C/T cg04342483 chr1:7259290 CAMTA1 -0.31 -4.44 -0.37 2e-5 Tourette's syndrome or obsessive-compulsive disorder; TGCT cis rs8050907 0.744 rs8058798 chr16:4531659 C/G cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT cis rs950027 0.620 rs1617984 chr15:45622662 A/G cg26924012 chr15:45694286 SPATA5L1 0.83 9.38 0.64 4.05e-16 Response to fenofibrate (adiponectin levels); TGCT cis rs377070 0.934 rs309414 chr4:123620912 A/C cg10495464 chr4:123653540 BBS12;LOC729338 0.54 5.23 0.43 6.92e-7 Mosquito bite size; TGCT cis rs7666738 0.830 rs2865981 chr4:99031493 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1443512 0.812 rs1975472 chr12:54337083 A/G cg17708016 chr12:54321992 NA 0.56 4.53 0.38 1.35e-5 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour); TGCT cis rs7513165 0.867 rs7524621 chr1:204160938 A/G cg12731349 chr1:204159619 KISS1 -0.53 -6.15 -0.48 9.97e-9 Psychosis proneness (hypomanic personality scale);Psychosis proneness (hypomanic personality scale and perceptual aberration scale);Psychosis proneness (hypomanic personality scale and revised social anhedonia scale);Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale); TGCT cis rs6087990 0.731 rs2424897 chr20:31338098 A/T cg13636640 chr20:31349939 DNMT3B 1.03 14.85 0.8 2.67e-29 Ulcerative colitis; TGCT cis rs6500602 0.592 rs7206782 chr16:4515145 A/C cg08645402 chr16:4508243 NA 0.21 5.06 0.41 1.47e-6 Schizophrenia; TGCT cis rs9467711 0.591 rs9467621 chr6:25851338 G/A cg16898833 chr6:26189333 HIST1H4D 1.16 5.51 0.44 2.03e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12541335 0.536 rs4266653 chr8:22169087 A/G cg02463440 chr8:22132932 PIWIL2 0.25 5.04 0.41 1.63e-6 Hypertriglyceridemia; TGCT cis rs1862618 0.756 rs832548 chr5:56183637 G/C cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs854765 0.663 rs3744115 chr17:17749822 G/A cg04398451 chr17:18023971 MYO15A 0.3 4.58 0.38 1.1e-5 Total body bone mineral density; TGCT cis rs9399137 0.561 rs11753985 chr6:135280438 C/T cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs6722750 0.846 rs13394665 chr2:64391431 A/C cg22352474 chr2:64371530 PELI1 -0.65 -6.2 -0.49 7.78e-9 Neuroticism; TGCT cis rs904251 0.861 rs1757183 chr6:37484790 C/T cg01843034 chr6:37503916 NA 0.47 5.94 0.47 2.74e-8 Cognitive performance; TGCT cis rs2760061 0.598 rs673726 chr1:228120173 T/C cg02753203 chr1:228287806 NA -0.34 -6.63 -0.51 9.15e-10 Diastolic blood pressure; TGCT cis rs7917772 0.503 rs7078435 chr10:104304766 T/C cg05855489 chr10:104503620 C10orf26 -0.59 -5.18 -0.42 8.7e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs597539 0.690 rs578791 chr11:68625809 C/T cg06112835 chr11:68658793 MRPL21 0.49 8.17 0.59 2.97e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs11190604 0.652 rs76629555 chr10:102191417 T/C cg16005271 chr10:102321736 NA 0.45 4.7 0.39 6.81e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9467773 0.583 rs1021373 chr6:26632457 G/A cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs477895 0.653 rs7102327 chr11:63908720 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.25 0.49 6.17e-9 Mean platelet volume; TGCT cis rs7216064 1.000 rs3206817 chr17:65892834 A/G cg12091567 chr17:66097778 LOC651250 -0.82 -6.24 -0.49 6.25e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs950169 0.922 rs12910334 chr15:84958318 G/A cg11189052 chr15:85197271 WDR73 0.81 6.22 0.49 6.89e-9 Schizophrenia; TGCT cis rs4665630 0.522 rs4665626 chr2:23883120 A/T cg08063864 chr2:24346004 PFN4;LOC375190 -1.22 -5.82 -0.46 4.81e-8 Hypertension; TGCT cis rs597539 0.652 rs514833 chr11:68657734 C/T cg04772025 chr11:68637568 NA 0.6 6.67 0.51 7.4e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs2549003 1.000 rs2549009 chr5:131826765 T/C cg02551604 chr5:131831745 NA 0.86 10.72 0.69 2.18e-19 Asthma (sex interaction); TGCT cis rs17253792 0.822 rs113692713 chr14:56087424 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs151997 0.962 rs28090 chr5:50177509 T/C cg06027927 chr5:50259733 NA 0.46 4.63 0.38 9.01e-6 Callous-unemotional behaviour; TGCT cis rs7726839 0.540 rs4957081 chr5:646418 G/C cg09021430 chr5:549028 NA -0.39 -5.37 -0.43 3.77e-7 Obesity-related traits; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg18538332 chr22:24372958 LOC391322 -0.88 -10.28 -0.68 2.68e-18 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1577917 0.958 rs10944147 chr6:86550786 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -5.02 -0.41 1.74e-6 Response to antipsychotic treatment; TGCT cis rs9894429 0.646 rs9904137 chr17:79613925 C/T cg18240062 chr17:79603768 NPLOC4 0.56 4.9 0.4 2.95e-6 Eye color traits; TGCT cis rs9486715 0.867 rs2499774 chr6:97006581 C/G cg18709589 chr6:96969512 KIAA0776 -0.86 -8.41 -0.6 8.44e-14 Headache; TGCT cis rs9393692 0.905 rs9393694 chr6:26279296 T/C cg00631329 chr6:26305371 NA -0.41 -6.09 -0.48 1.34e-8 Educational attainment; TGCT cis rs1536827 0.541 rs11592589 chr10:135363657 G/A cg14503168 chr10:134895446 NA -0.55 -4.53 -0.38 1.36e-5 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs7811142 0.775 rs1059129 chr7:99926522 A/G cg00814883 chr7:100076585 TSC22D4 -0.82 -8.23 -0.59 2.14e-13 Platelet count; TGCT cis rs7412746 0.634 rs12562939 chr1:150951452 A/C cg09365446 chr1:150670422 GOLPH3L 0.35 4.88 0.4 3.17e-6 Melanoma; TGCT cis rs12765878 0.756 rs6584579 chr10:105645725 A/G cg11005552 chr10:105648138 OBFC1 -0.43 -6.97 -0.53 1.67e-10 Coronary artery disease; TGCT cis rs514406 0.800 rs4926930 chr1:53217335 A/G cg25767906 chr1:53392781 SCP2 0.48 5.36 0.43 3.95e-7 Monocyte count; TGCT cis rs2594989 0.837 rs2454497 chr3:11501597 T/C cg26283222 chr3:11613257 VGLL4 -0.21 -4.49 -0.37 1.58e-5 Circulating chemerin levels; TGCT cis rs6089829 0.962 rs9679865 chr20:61666132 C/G cg18188782 chr20:61659543 NA 0.46 5.55 0.45 1.61e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs2832191 0.791 rs2832202 chr21:30501342 G/A cg08807101 chr21:30365312 RNF160 -0.65 -6.08 -0.48 1.35e-8 Dental caries; TGCT cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg13695892 chr22:41940480 POLR3H 0.92 9.08 0.63 2.08e-15 Vitiligo; TGCT cis rs11190604 0.943 rs11190581 chr10:102243387 T/G cg16342193 chr10:102329863 NA -0.4 -5.34 -0.43 4.36e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11785400 0.793 rs9297970 chr8:143723386 C/T cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs7044106 0.762 rs7044226 chr9:123466328 G/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.64 6.82 0.52 3.48e-10 Hip circumference adjusted for BMI; TGCT cis rs61680841 0.627 rs16945457 chr15:91795758 A/C cg16895464 chr15:91415119 FURIN -0.7 -4.55 -0.38 1.28e-5 Age-related hearing impairment; TGCT cis rs7089973 0.872 rs7923295 chr10:116625159 C/G cg03647239 chr10:116582469 FAM160B1 -0.5 -4.44 -0.37 2e-5 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7727544 0.716 rs11949055 chr5:131576737 T/C cg21474247 chr5:131268130 NA 0.31 4.63 0.38 8.95e-6 Blood metabolite levels; TGCT trans rs783396 0.892 rs6906338 chr6:106969995 T/A cg27564810 chr2:201635376 AOX2P -0.42 -6.64 -0.51 9.02e-10 Stroke; TGCT cis rs17253792 0.822 rs77420254 chr14:56069646 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs736408 0.812 rs6778329 chr3:52824610 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.52 4.98 0.41 2.05e-6 Bipolar disorder; TGCT cis rs6988636 1.000 rs62521826 chr8:124186668 C/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9611565 0.694 rs202613 chr22:41821993 C/A cg03806693 chr22:41940476 POLR3H 1.16 13.52 0.77 3.78e-26 Vitiligo; TGCT cis rs10504229 0.861 rs114700910 chr8:58170642 C/T cg08219700 chr8:58056026 NA 0.3 4.57 0.38 1.14e-5 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.753 rs11932536 chr4:98930105 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10193935 0.901 rs1044562 chr2:42516884 C/G cg27598129 chr2:42591480 NA -0.42 -5.72 -0.46 7.48e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs59698941 0.550 rs60042615 chr5:132193220 A/G cg21474247 chr5:131268130 NA 0.32 4.82 0.4 4.16e-6 Apolipoprotein A-IV levels; TGCT cis rs7336332 0.569 rs57724994 chr13:28010389 T/C cg22138327 chr13:27999177 GTF3A 0.68 4.99 0.41 2.01e-6 Weight; TGCT cis rs56399783 0.808 rs73049331 chr7:2799911 C/T cg19731401 chr7:2775893 GNA12 0.35 4.92 0.4 2.7e-6 Childhood ear infection; TGCT cis rs7412746 0.611 rs10788794 chr1:150728676 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.57 0.38 1.15e-5 Melanoma; TGCT cis rs12421382 0.659 rs1371331 chr11:109382578 G/A cg16359550 chr11:109292809 C11orf87 0.4 4.5 0.37 1.54e-5 Schizophrenia; TGCT cis rs1670533 0.818 rs585735 chr4:1080391 G/C cg27284194 chr4:1044797 NA 0.68 5.84 0.46 4.28e-8 Recombination rate (females); TGCT cis rs4378999 0.800 rs2609031 chr3:50857796 C/T cg11728787 chr3:50609551 HEMK1 0.36 4.58 0.38 1.11e-5 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); TGCT cis rs12048904 0.619 rs10875347 chr1:101333737 T/C cg16556008 chr1:101360663 SLC30A7;EXTL2 0.88 8.3 0.6 1.46e-13 Multiple sclerosis; TGCT cis rs10479542 0.766 rs7733389 chr5:178974997 C/T cg21226059 chr5:178986404 RUFY1 0.46 5.18 0.42 8.68e-7 Lung cancer; TGCT cis rs7659604 0.540 rs4455438 chr4:122669550 G/A cg19748678 chr4:122722346 EXOSC9 -0.5 -4.95 -0.41 2.37e-6 Type 2 diabetes; TGCT cis rs4819052 0.679 rs2236450 chr21:46702553 T/C cg19498844 chr21:46707878 POFUT2;LOC642852 0.66 6.48 0.5 1.93e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7829975 0.508 rs1594437 chr8:8825875 T/C cg06636001 chr8:8085503 FLJ10661 0.68 5.58 0.45 1.46e-7 Mood instability; TGCT cis rs2762353 0.808 rs1185568 chr6:25834428 T/A cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.14e-6 Blood metabolite levels; TGCT cis rs798554 0.759 rs2644291 chr7:2890456 T/C cg13628971 chr7:2884303 GNA12 0.56 4.48 0.37 1.69e-5 Height; TGCT cis rs4478858 0.698 rs7543348 chr1:31804805 A/C cg07478791 chr1:31886160 SERINC2 -0.51 -4.95 -0.41 2.33e-6 Alcohol dependence; TGCT cis rs59197085 0.636 rs3823481 chr7:128469381 G/A cg00260937 chr7:128520193 KCP 0.46 4.82 0.4 4.15e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs7439150 0.738 rs72681215 chr4:155479803 C/A cg22130008 chr4:155548532 NA -0.44 -5.59 -0.45 1.36e-7 Fibrinogen levels; TGCT cis rs1982963 0.950 rs2645738 chr14:52513202 G/A cg10843707 chr14:52510701 NID2 -0.44 -6.81 -0.52 3.72e-10 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs41271473 0.526 rs72765760 chr1:228743222 G/A cg10167378 chr1:228756711 NA 0.74 4.61 0.38 9.77e-6 Chronic lymphocytic leukemia; TGCT cis rs514406 0.861 rs503015 chr1:53254456 T/C cg08859206 chr1:53392774 SCP2 0.4 5.96 0.47 2.46e-8 Monocyte count; TGCT cis rs9300255 0.510 rs1727323 chr12:123698790 T/C cg00376283 chr12:123451042 ABCB9 0.73 5.67 0.45 9.46e-8 Neutrophil percentage of white cells; TGCT cis rs28386778 0.897 rs6504177 chr17:61812655 C/T cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.78 0.39 4.79e-6 Prudent dietary pattern; TGCT cis rs2243480 0.706 rs6460257 chr7:65196780 C/T cg07424592 chr7:64974309 NA 0.83 5.36 0.43 3.95e-7 Diabetic kidney disease; TGCT cis rs3785574 0.924 rs2584641 chr17:61862889 A/G cg06601766 chr17:61851465 DDX42;CCDC47 0.57 5.08 0.41 1.37e-6 Height; TGCT cis rs933688 1.000 rs332544 chr5:90778848 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.94 8.95 0.63 4.39e-15 Smoking behavior; TGCT cis rs727563 0.635 rs2899348 chr22:42164516 C/G cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Crohn's disease;Inflammatory bowel disease; TGCT cis rs797680 0.856 rs7512911 chr1:93715818 C/G cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7590720 0.802 rs12694383 chr2:216915838 A/G cg12620499 chr2:216877984 MREG 0.79 7.33 0.55 2.61e-11 Alcohol dependence; TGCT cis rs6598955 0.515 rs61776655 chr1:26541430 T/C cg01614726 chr1:26633154 UBXN11 0.49 4.67 0.39 7.59e-6 Obesity-related traits; TGCT cis rs7953249 0.564 rs1183910 chr12:121420807 G/A cg02403541 chr12:121454288 C12orf43 0.66 5.85 0.47 4.01e-8 Invasive epithelial ovarian cancer;High-grade serous ovarian cancer;Chronic obstructive pulmonary disease-related biomarkers;N-glycan levels;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs9611565 0.512 rs139571 chr22:42214238 G/A cg06481639 chr22:41940642 POLR3H -0.69 -6.02 -0.48 1.83e-8 Vitiligo; TGCT cis rs12477438 0.520 rs11123762 chr2:99727789 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs11718455 0.960 rs13065591 chr3:43996585 T/C cg08738300 chr3:44038990 NA 0.81 6.02 0.48 1.8e-8 Coronary artery disease; TGCT cis rs12950390 0.776 rs4793646 chr17:45853966 A/C cg06532163 chr17:45867833 NA 0.37 5.87 0.47 3.74e-8 IgG glycosylation; TGCT cis rs4862750 0.872 rs56389997 chr4:187894796 A/C cg10295955 chr4:187884368 NA -1.02 -15.6 -0.81 5.02e-31 Lobe attachment (rater-scored or self-reported); TGCT cis rs2688608 0.588 rs10128205 chr10:75469648 C/G cg15838173 chr10:75533400 FUT11 -0.32 -5.06 -0.41 1.48e-6 Inflammatory bowel disease; TGCT cis rs13082711 0.522 rs594466 chr3:27362069 A/G cg02860705 chr3:27208620 NA -0.31 -5.17 -0.42 8.93e-7 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs10927875 0.830 rs1763610 chr1:16335527 C/G cg21385522 chr1:16154831 NA -0.57 -6.18 -0.49 8.6e-9 Dilated cardiomyopathy; TGCT cis rs56235845 0.694 rs36102285 chr5:176774018 C/T cg16006841 chr5:176797999 RGS14 0.52 7.69 0.57 3.9e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg16680214 chr1:154839983 KCNN3 -0.36 -7.33 -0.55 2.59e-11 Prostate cancer; TGCT cis rs9650657 0.515 rs7820860 chr8:10950396 C/G cg21775007 chr8:11205619 TDH -0.54 -5.08 -0.41 1.37e-6 Neuroticism; TGCT cis rs910316 1.000 rs12589815 chr14:75544101 C/T cg08847533 chr14:75593920 NEK9 0.96 10.53 0.69 6.43e-19 Height; TGCT cis rs9611565 0.506 rs2024567 chr22:41699206 G/C cg13695892 chr22:41940480 POLR3H -0.67 -6.2 -0.49 7.58e-9 Vitiligo; TGCT cis rs1577917 1.000 rs12663651 chr6:86701655 T/G cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs2361718 0.564 rs2304844 chr17:78084507 G/C cg09238746 chr17:78121135 EIF4A3 -0.96 -8.98 -0.63 3.64e-15 Yeast infection; TGCT cis rs72781680 1.000 rs6751655 chr2:24155478 A/G cg08917208 chr2:24149416 ATAD2B 0.8 4.94 0.41 2.47e-6 Lymphocyte counts; TGCT cis rs477895 1.000 rs11600990 chr11:64082807 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.68 5.19 0.42 8.41e-7 Mean platelet volume; TGCT cis rs5769765 0.728 rs6520064 chr22:50294469 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs11105298 0.891 rs11105310 chr12:89918677 C/A cg00757033 chr12:89920650 WDR51B 0.32 5.13 0.42 1.11e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9303401 0.614 rs2007993 chr17:56590643 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs9325144 0.532 rs1352121 chr12:39130696 A/G cg13010199 chr12:38710504 ALG10B -0.52 -4.68 -0.39 7.29e-6 Morning vs. evening chronotype; TGCT cis rs1568889 0.838 rs11030187 chr11:28044391 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.92 11.42 0.72 4.31e-21 Bipolar disorder; TGCT cis rs10504229 0.728 rs72650868 chr8:58155568 G/C cg20607798 chr8:58055168 NA 0.5 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs7523273 0.597 rs2796265 chr1:207920788 A/G cg22525895 chr1:207977042 MIR29B2 -0.44 -6.48 -0.5 1.93e-9 Schizophrenia; TGCT cis rs597539 0.615 rs629426 chr11:68671104 A/G cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.85 8.16 0.59 3.19e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs59197085 0.636 rs2270593 chr7:128456234 C/T cg00260937 chr7:128520193 KCP 0.47 4.98 0.41 2.1e-6 Reading disability or specific language impairment (pleiotropy);Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy); TGCT cis rs7975161 0.579 rs7962423 chr12:104710910 G/A cg25273343 chr12:104657179 TXNRD1 -0.36 -5.0 -0.41 1.9e-6 Toenail selenium levels; TGCT cis rs13108904 0.837 rs4519749 chr4:1280102 A/G cg00684032 chr4:1343700 KIAA1530 0.23 4.95 0.41 2.36e-6 Obesity-related traits; TGCT cis rs981844 1.000 rs2263434 chr4:154658312 A/G cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs7113874 0.569 rs9737401 chr11:8595652 C/T cg14521421 chr11:8862019 ST5 0.28 4.44 0.37 1.96e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs2739330 1.000 rs2739330 chr22:24295286 T/C cg20007245 chr22:24372913 LOC391322 -0.65 -6.45 -0.5 2.24e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs75686122 0.892 rs117436056 chr8:104564376 A/G cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs9372498 0.536 rs10484286 chr6:118956447 T/C cg21191810 chr6:118973309 C6orf204 -0.38 -4.98 -0.41 2.04e-6 Diastolic blood pressure; TGCT cis rs7772486 0.686 rs857883 chr6:145969214 G/T cg13319975 chr6:146136371 FBXO30 0.54 4.98 0.41 2.09e-6 Lobe attachment (rater-scored or self-reported); TGCT trans rs629535 0.814 rs55873935 chr8:70081646 G/A cg21567404 chr3:27674614 NA -0.57 -8.99 -0.63 3.38e-15 Dupuytren's disease; TGCT cis rs17443541 0.516 rs1450569 chr2:200443111 A/T cg00055341 chr2:200446845 NA -0.32 -4.47 -0.37 1.73e-5 Intelligence (multi-trait analysis); TGCT cis rs10256972 0.616 rs4585652 chr7:1145396 A/G cg18765753 chr7:1198926 ZFAND2A -0.49 -5.79 -0.46 5.48e-8 Longevity;Endometriosis; TGCT cis rs28595532 1.000 rs73842212 chr4:119638122 A/G cg14228332 chr4:119757509 SEC24D 1.02 5.39 0.44 3.44e-7 Cannabis dependence symptom count; TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg22166914 chr1:53195759 ZYG11B 0.3 4.87 0.4 3.29e-6 Monocyte count; TGCT cis rs7224685 0.569 rs58357241 chr17:3996641 T/C cg09580393 chr17:4869866 SPAG7 -0.39 -4.49 -0.37 1.62e-5 Type 2 diabetes; TGCT cis rs3848445 1.000 rs7214411 chr17:14288990 C/T cg05083273 chr17:13688564 NA -0.63 -4.45 -0.37 1.92e-5 Protein quantitative trait loci; TGCT cis rs3731896 1.000 rs3731896 chr2:220146402 C/T cg00496455 chr2:220118770 TUBA4A;TUBA4B 0.78 5.54 0.45 1.71e-7 Educational attainment; TGCT cis rs1975974 0.590 rs113830378 chr17:21744147 G/C cg18423549 chr17:21743878 NA -0.65 -5.7 -0.46 8.21e-8 Psoriasis; TGCT cis rs7617773 1.000 rs11711766 chr3:48193170 G/C cg11946769 chr3:48343235 NME6 -0.59 -5.25 -0.43 6.49e-7 Coronary artery disease; TGCT trans rs2727020 0.755 rs652655 chr11:49251293 G/A cg15704280 chr7:45808275 SEPT13 0.73 8.35 0.6 1.16e-13 Coronary artery disease; TGCT cis rs12497850 0.931 rs9867373 chr3:48960938 A/T cg18654377 chr3:49208889 KLHDC8B -0.42 -5.52 -0.44 1.93e-7 Parkinson's disease; TGCT cis rs142328051 1 rs142328051 chr1:44371441 T/C cg12908607 chr1:44402522 ARTN 0.72 5.02 0.41 1.72e-6 Educational attainment (years of education); TGCT cis rs17401966 0.931 rs12409754 chr1:10457540 T/C cg19773385 chr1:10388646 KIF1B -0.23 -5.42 -0.44 2.97e-7 Hepatocellular carcinoma; TGCT cis rs13392177 0.684 rs6720105 chr2:219080718 G/A cg00012203 chr2:219082015 ARPC2 -0.79 -8.02 -0.58 6.73e-13 Pyoderma gangrenosum in inflammatory bowel disease; TGCT cis rs2739330 0.796 rs1006771 chr22:24314006 G/T cg11905131 chr22:24372483 LOC391322 -0.78 -8.26 -0.6 1.85e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs903263 0.901 rs7512288 chr1:84599007 C/T cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.73e-6 Breast cancer (male); TGCT cis rs7208859 0.623 rs9894709 chr17:29078454 G/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17376456 0.877 rs55832164 chr5:93436579 C/T cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs7175404 0.591 rs57153897 chr15:94057102 G/A cg18324227 chr15:93584571 NA 0.48 4.51 0.38 1.49e-5 Attention deficit hyperactivity disorder; TGCT cis rs6746896 0.959 rs72809838 chr2:97428320 G/A cg26085987 chr2:97230376 NA 0.19 4.63 0.38 8.95e-6 Bipolar disorder; TGCT cis rs1059312 0.966 rs7135968 chr12:129280066 G/A cg09035930 chr12:129282057 SLC15A4 0.59 11.76 0.73 6.45e-22 Systemic lupus erythematosus; TGCT cis rs9611565 0.649 rs5751144 chr22:42128097 A/G cg17554472 chr22:41940697 POLR3H -0.45 -4.84 -0.4 3.72e-6 Vitiligo; TGCT cis rs7666738 0.830 rs34628820 chr4:99004764 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.918 rs73176685 chr22:41781094 C/G cg06634786 chr22:41940651 POLR3H -0.73 -6.8 -0.52 3.93e-10 Vitiligo; TGCT cis rs7246657 0.943 rs2291004 chr19:37997952 C/A cg18154014 chr19:37997991 ZNF793 0.88 5.73 0.46 7.14e-8 Coronary artery calcification; TGCT cis rs1865760 0.865 rs9393678 chr6:25945819 C/T cg16482183 chr6:26056742 HIST1H1C 0.53 4.88 0.4 3.14e-6 Height; TGCT trans rs3780486 0.846 rs10971420 chr9:33125000 T/C cg04842962 chr6:43655489 MRPS18A 1.22 16.02 0.82 5.54e-32 IgG glycosylation; TGCT cis rs2120019 1.000 rs8033837 chr15:75353975 A/C cg17294928 chr15:75287854 SCAMP5 -0.81 -6.21 -0.49 7.41e-9 Blood trace element (Zn levels); TGCT cis rs6964587 0.934 rs7798973 chr7:91588360 G/A cg17063962 chr7:91808500 NA 0.91 9.99 0.67 1.32e-17 Breast cancer; TGCT cis rs644799 0.965 rs545342 chr11:95545369 T/C cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7095607 0.935 rs12774635 chr10:69950477 T/A cg18986048 chr10:69913749 MYPN 0.46 4.93 0.41 2.54e-6 Lung function (FVC); TGCT cis rs4074961 0.527 rs2294875 chr1:38052445 C/T cg11397548 chr1:38022522 DNALI1 0.42 4.86 0.4 3.47e-6 Axial length; TGCT cis rs7829975 0.774 rs11249893 chr8:8700851 C/T cg06636001 chr8:8085503 FLJ10661 0.72 6.67 0.51 7.64e-10 Mood instability; TGCT cis rs116095464 0.558 rs6882584 chr5:223411 A/C cg22857025 chr5:266934 NA -0.31 -6.32 -0.49 4.33e-9 Breast cancer; TGCT cis rs2180341 1.000 rs6569477 chr6:127589302 T/A cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs12142240 0.698 rs1984490 chr1:46858734 C/T cg00530320 chr1:46809349 NSUN4 -0.29 -5.88 -0.47 3.51e-8 Menopause (age at onset); TGCT cis rs826838 0.804 rs6580755 chr12:39159190 C/T cg13010199 chr12:38710504 ALG10B 0.83 6.7 0.52 6.57e-10 Heart rate; TGCT cis rs7607369 0.759 rs10179708 chr2:219390967 T/A cg02176678 chr2:219576539 TTLL4 -0.47 -6.65 -0.51 8.44e-10 Red blood cell count;Amyotrophic lateral sclerosis; TGCT trans rs208515 0.525 rs12193560 chr6:66690457 A/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.93 10.3 0.68 2.34e-18 Exhaled nitric oxide levels; TGCT cis rs61990749 0.686 rs11159288 chr14:78216972 G/A cg02301378 chr14:78227641 SNW1;C14orf178 0.6 4.45 0.37 1.88e-5 Fibroblast growth factor basic levels; TGCT cis rs5769765 0.773 rs7410291 chr22:50300078 A/G cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -10.56 -0.69 5.6e-19 Schizophrenia; TGCT cis rs9926296 0.712 rs459920 chr16:89730827 T/C cg21285383 chr16:89894308 SPIRE2 -0.32 -4.52 -0.38 1.42e-5 Vitiligo; TGCT cis rs9611565 0.527 rs73178638 chr22:41942904 T/C cg03806693 chr22:41940476 POLR3H -1.13 -13.26 -0.77 1.59e-25 Vitiligo; TGCT cis rs9399135 0.967 rs2297340 chr6:135376058 T/C cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs1371867 0.875 rs28595052 chr8:101327553 G/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs782590 0.935 rs62165197 chr2:55801812 C/T cg03859395 chr2:55845619 SMEK2 0.92 11.39 0.72 5.08e-21 Metabolic syndrome; TGCT cis rs4478037 1.000 rs4074416 chr3:33161729 A/G cg19404215 chr3:33155277 CRTAP 1.33 8.79 0.62 1.04e-14 Major depressive disorder; TGCT cis rs1799949 0.930 rs4584865 chr17:41424919 C/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs394563 0.591 rs237029 chr6:149717425 A/G cg16235748 chr6:149772707 ZC3H12D -0.44 -4.9 -0.4 2.87e-6 Dupuytren's disease; TGCT cis rs2242116 1.000 rs2168443 chr3:46947087 A/T cg23352942 chr3:46931381 PTH1R 0.32 4.8 0.4 4.51e-6 Birth weight; TGCT cis rs6840360 1.000 rs6535819 chr4:152651503 A/G cg22705602 chr4:152727874 NA -0.25 -4.45 -0.37 1.91e-5 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs252887 chr5:56166188 A/G cg24531977 chr5:56204891 C5orf35 -0.74 -7.1 -0.54 8.53e-11 Initial pursuit acceleration; TGCT cis rs13191362 0.938 rs35395472 chr6:163008493 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT trans rs4650994 1.000 rs4076205 chr1:178534157 G/A cg05059571 chr16:84539110 KIAA1609 -0.4 -7.39 -0.55 1.92e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs3820068 0.532 rs72647105 chr1:15935238 C/G cg05660106 chr1:15850417 CASP9 0.83 8.16 0.59 3.26e-13 Systolic blood pressure; TGCT cis rs11190604 1.000 rs11190570 chr10:102227702 G/C cg23241863 chr10:102295624 HIF1AN 0.62 4.87 0.4 3.27e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6121246 0.697 rs8118150 chr20:30436088 G/A cg18721089 chr20:30220636 NA -0.45 -4.75 -0.39 5.43e-6 Mean corpuscular hemoglobin; TGCT cis rs10883723 0.738 rs715438 chr10:104258303 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.81 8.36 0.6 1.1e-13 Allergic disease (asthma, hay fever or eczema); TGCT cis rs3087591 0.708 rs8067440 chr17:29708155 A/T cg24425628 chr17:29625626 OMG;NF1 0.4 5.77 0.46 5.86e-8 Hip circumference; TGCT cis rs6433895 1.000 rs6759865 chr2:182017385 A/G cg16904960 chr2:182549928 NA 0.34 4.47 0.37 1.77e-5 Lymphocyte counts; TGCT cis rs11690935 0.959 rs10204622 chr2:172588982 C/T cg13550731 chr2:172543902 DYNC1I2 -1.18 -12.51 -0.75 9.78e-24 Schizophrenia; TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg14820908 chr5:178986412 RUFY1 0.49 4.94 0.41 2.46e-6 Lung cancer; TGCT cis rs7474896 0.537 rs1779068 chr10:38250785 G/A cg13720705 chr10:37990370 NA -0.34 -4.6 -0.38 1.04e-5 Obesity (extreme); TGCT cis rs35146811 0.735 rs1061230 chr7:99807265 G/A cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs9368481 0.700 rs6911401 chr6:26913214 C/G cg26531700 chr6:26746687 NA 0.7 6.39 0.5 3.12e-9 Autism spectrum disorder or schizophrenia; TGCT cis rs7819412 0.511 rs10108511 chr8:11435516 T/C cg27411982 chr8:10470053 RP1L1 -0.21 -4.59 -0.38 1.07e-5 Triglycerides; TGCT cis rs2070488 0.965 rs4679053 chr3:38523495 G/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.88 8.99 0.63 3.5e-15 Electrocardiographic conduction measures; TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs7666738 0.830 rs6853266 chr4:99047528 G/T cg05340658 chr4:99064831 C4orf37 0.55 6.29 0.49 4.98e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs9611565 0.512 rs4822052 chr22:42193741 G/A cg06634786 chr22:41940651 POLR3H -0.82 -8.03 -0.59 6.31e-13 Vitiligo; TGCT cis rs28735056 0.587 rs8093548 chr18:77636451 G/A cg20368463 chr18:77673604 PQLC1 -0.45 -5.52 -0.44 1.89e-7 Schizophrenia; TGCT cis rs10276381 0.786 rs740261 chr7:28241276 A/G cg23620719 chr7:28220237 JAZF1 1.0 5.39 0.44 3.36e-7 Crohn's disease; TGCT cis rs7666738 0.688 rs4632667 chr4:98748299 A/G cg24818145 chr4:99064322 C4orf37 0.62 4.67 0.39 7.82e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs5750830 0.620 rs1007337 chr22:39781585 C/T cg01416388 chr22:39784598 NA -0.63 -6.06 -0.48 1.52e-8 Intelligence (multi-trait analysis); TGCT cis rs6430585 0.527 rs59413285 chr2:136444185 G/T cg07169764 chr2:136633963 MCM6 1.0 9.14 0.63 1.51e-15 Corneal structure; TGCT cis rs1555895 0.576 rs7071801 chr10:854011 T/C cg02193355 chr10:851439 NA 0.2 4.54 0.38 1.3e-5 Survival in rectal cancer; TGCT cis rs4509693 0.891 rs10748797 chr10:102502173 A/C cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs2046867 0.818 rs62249874 chr3:72911202 G/C cg25664220 chr3:72788482 NA -0.56 -7.45 -0.56 1.38e-11 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs6582630 0.573 rs12319414 chr12:38267440 T/C cg26384229 chr12:38710491 ALG10B -0.54 -4.7 -0.39 6.68e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs4478858 0.709 rs937786 chr1:31857869 G/A cg00250761 chr1:31883323 NA 0.25 4.54 0.38 1.3e-5 Alcohol dependence; TGCT cis rs6906287 0.647 rs67832971 chr6:118832205 C/T cg21191810 chr6:118973309 C6orf204 0.26 4.49 0.37 1.58e-5 Electrocardiographic conduction measures; TGCT cis rs6951245 1.000 rs11761941 chr7:1097183 G/A cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2243480 1.000 rs313798 chr7:65493031 A/G cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs7811142 1.000 rs67040465 chr7:100083078 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs4819052 0.807 rs1075788 chr21:46666564 T/G cg06618935 chr21:46677482 NA -0.37 -5.8 -0.46 5.29e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT trans rs208520 0.874 rs208469 chr6:66915891 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -9.95 -0.67 1.64e-17 Exhaled nitric oxide output; TGCT cis rs7954584 0.560 rs745327 chr12:122456524 T/C cg13699009 chr12:122356056 WDR66 -0.23 -4.73 -0.39 5.92e-6 Mean corpuscular volume; TGCT cis rs2033711 0.811 rs9304814 chr19:58951811 C/A cg04608855 chr19:58913158 NA 0.6 5.86 0.47 3.99e-8 Uric acid clearance; TGCT cis rs2370759 1.000 rs77165999 chr10:32577131 T/C cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs12042938 0.507 rs1655299 chr1:231732161 C/T cg04892437 chr1:231737901 TSNAX-DISC1 -0.42 -4.83 -0.4 3.98e-6 Neuranatomic and neurocognitive phenotypes; TGCT cis rs6534347 0.573 rs11098666 chr4:123507914 A/G cg10583651 chr4:123538969 IL21 -0.32 -4.49 -0.37 1.63e-5 Type 1 diabetes; TGCT cis rs314590 1.000 rs314590 chr7:4474132 G/A cg10785373 chr7:4456119 NA -0.41 -4.48 -0.37 1.7e-5 Obesity-related traits; TGCT cis rs908922 0.676 rs1538082 chr1:152517304 A/G cg20991723 chr1:152506922 NA 0.45 6.11 0.48 1.18e-8 Hair morphology; TGCT cis rs8177179 0.967 rs6439434 chr3:133450371 T/G cg24879335 chr3:133465180 TF 0.37 5.02 0.41 1.72e-6 Iron status biomarkers (transferrin levels); TGCT cis rs6671200 0.607 rs1927043 chr1:95667251 G/A cg26537280 chr1:95699037 RWDD3 -0.53 -4.98 -0.41 2.1e-6 Stearic acid (18:0) levels; TGCT cis rs7599312 0.517 rs10192988 chr2:213407782 T/G cg20637307 chr2:213403960 ERBB4 0.92 11.46 0.72 3.6e-21 BMI (adjusted for smoking behaviour);BMI in non-smokers;Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11098499 0.954 rs11098526 chr4:120390359 C/T cg09307838 chr4:120376055 NA 0.69 6.56 0.51 1.31e-9 Corneal astigmatism; TGCT cis rs6831352 0.918 rs7670060 chr4:100059568 G/T cg12011299 chr4:100065546 ADH4 -0.41 -4.96 -0.41 2.29e-6 Alcohol dependence; TGCT cis rs2013441 1.000 rs2703787 chr17:20158665 A/G cg23224458 chr17:20280056 CCDC144C -0.38 -4.63 -0.38 9.19e-6 Obesity-related traits; TGCT cis rs1865760 0.593 rs9393676 chr6:25936944 G/A cg03264133 chr6:25882463 NA -0.5 -5.2 -0.42 8.12e-7 Height; TGCT cis rs2153535 0.580 rs1335633 chr6:8448800 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.76 0.46 6.39e-8 Motion sickness; TGCT cis rs4919694 1.000 rs111622998 chr10:104953021 C/A cg04362960 chr10:104952993 NT5C2 1.07 7.15 0.54 6.62e-11 Arsenic metabolism; TGCT cis rs765787 0.530 rs2668737 chr15:45522799 C/T cg24006582 chr15:45444508 DUOX1 -0.25 -5.53 -0.44 1.82e-7 Uric acid levels; TGCT cis rs1062177 1.000 rs17804178 chr5:151197729 T/G cg12924095 chr5:151150029 G3BP1 0.35 5.05 0.41 1.53e-6 Preschool internalizing problems; TGCT cis rs2996428 0.667 rs11578581 chr1:3770642 G/A cg13057898 chr1:3703894 LRRC47 0.21 4.64 0.38 8.81e-6 Red cell distribution width; TGCT cis rs10504229 1.000 rs72650899 chr8:58180525 G/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.24 -0.43 6.7e-7 Developmental language disorder (linguistic errors); TGCT cis rs2440129 0.611 rs1042357 chr17:6905061 T/G cg03760483 chr17:6899297 ALOX12 0.48 5.5 0.44 2.11e-7 Tonsillectomy; TGCT cis rs11098499 0.774 rs11098505 chr4:120284627 C/T cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs6460942 0.908 rs6948654 chr7:12418546 T/A cg06484146 chr7:12443880 VWDE -0.62 -6.21 -0.49 7.17e-9 Coronary artery disease; TGCT cis rs6032067 0.543 rs7272524 chr20:43908694 A/T cg16667508 chr20:43936853 MATN4;RBPJL -0.39 -6.18 -0.49 8.63e-9 Blood protein levels; TGCT cis rs751728 0.664 rs4711349 chr6:33740592 C/T cg13859433 chr6:33739653 LEMD2 -0.32 -5.6 -0.45 1.29e-7 Crohn's disease; TGCT cis rs7216064 0.531 rs6504573 chr17:66015963 C/T cg12091567 chr17:66097778 LOC651250 -0.77 -6.54 -0.51 1.48e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs4820539 0.966 rs2283803 chr22:23454881 G/A cg14186256 chr22:23484241 RTDR1 0.92 10.78 0.7 1.6e-19 Bone mineral density; TGCT cis rs7772486 0.686 rs2142983 chr6:146069701 G/C cg23711669 chr6:146136114 FBXO30 -0.88 -9.63 -0.65 1.01e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4880487 0.888 rs10794730 chr10:1247022 C/T cg03183215 chr10:1252341 ADARB2 -0.3 -5.77 -0.46 6.09e-8 Migraine; TGCT cis rs10256972 0.504 rs2949178 chr7:1209925 T/C cg18765753 chr7:1198926 ZFAND2A -0.55 -6.86 -0.52 2.84e-10 Longevity;Endometriosis; TGCT cis rs9372498 0.536 rs12333080 chr6:118845410 A/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT cis rs5769707 0.967 rs2051626 chr22:50008973 G/A cg05373962 chr22:49881684 NA -0.3 -6.1 -0.48 1.22e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs9467773 0.620 rs9295701 chr6:26627508 T/C cg11502198 chr6:26597334 ABT1 0.54 4.97 0.41 2.14e-6 Intelligence (multi-trait analysis); TGCT cis rs1799949 1.000 rs4534897 chr17:41431808 A/G cg10047753 chr17:41438598 NA 0.94 9.23 0.64 9.06e-16 Menopause (age at onset); TGCT cis rs9399135 0.935 rs11760000 chr6:135370496 G/A cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.28e-6 Red blood cell count; TGCT cis rs9381040 0.655 rs4140578 chr6:41041829 A/G cg03526776 chr6:41159608 TREML2 0.27 5.34 0.43 4.21e-7 Alzheimer's disease (late onset); TGCT cis rs35306767 0.855 rs34318754 chr10:890714 G/A cg26597838 chr10:835615 NA 0.8 12.11 0.74 9.26e-23 Eosinophil percentage of granulocytes; TGCT trans rs6089829 0.962 rs6062780 chr20:61666648 T/C cg13615516 chr5:77269221 NA 0.68 8.54 0.61 3.97e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs1124769 0.502 rs12911207 chr15:51069296 T/C cg23028286 chr15:51614521 CYP19A1 0.19 4.47 0.37 1.75e-5 Cognitive performance; TGCT cis rs4819052 0.851 rs914214 chr21:46697820 G/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4711336 1.000 rs4711337 chr6:33659987 T/C cg14003231 chr6:33640908 ITPR3 0.28 4.51 0.38 1.49e-5 Height; TGCT cis rs939658 1.000 rs11072826 chr15:79461516 C/T cg17916960 chr15:79447300 NA 0.52 8.43 0.6 7.56e-14 Refractive error; TGCT cis rs7698623 0.717 rs4147245 chr4:88779237 A/C cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs4253772 0.550 rs715515 chr22:46720921 G/A cg24881330 chr22:46731750 TRMU 1.04 5.38 0.44 3.54e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs28386778 0.787 rs2665827 chr17:61961350 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.54 4.86 0.4 3.47e-6 Prudent dietary pattern; TGCT trans rs7618501 0.633 rs2526748 chr3:50080439 A/G cg21659725 chr3:3221576 CRBN -0.76 -9.03 -0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs1862618 0.853 rs6885541 chr5:56110857 G/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs514406 0.644 rs6661196 chr1:53203664 A/G cg08859206 chr1:53392774 SCP2 0.35 5.07 0.41 1.39e-6 Monocyte count; TGCT cis rs877282 0.945 rs12776447 chr10:790625 A/G cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs4242434 0.787 rs1545837 chr8:22477807 T/C cg03733263 chr8:22462867 KIAA1967 1.04 15.21 0.81 4.06e-30 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs7904368 0.806 rs7099178 chr10:16862578 C/G cg14835575 chr10:16859367 RSU1 0.65 6.89 0.53 2.45e-10 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs7917772 0.636 rs2249850 chr10:104512006 A/G cg05855489 chr10:104503620 C10orf26 -0.66 -5.19 -0.42 8.45e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2486288 0.656 rs6493143 chr15:45570781 G/T cg26924012 chr15:45694286 SPATA5L1 -0.78 -7.55 -0.56 8e-12 Glomerular filtration rate; TGCT cis rs644148 0.933 rs565819 chr19:44967714 A/G cg15540054 chr19:45004280 ZNF180 0.59 5.25 0.43 6.49e-7 Personality dimensions; TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg24503407 chr1:205819492 PM20D1 -0.55 -7.74 -0.57 3.05e-12 Menarche (age at onset); TGCT cis rs2439831 1.000 rs2439850 chr15:43784854 C/G cg02155558 chr15:43621948 ADAL;LCMT2 1.01 8.19 0.59 2.67e-13 Lung cancer in ever smokers; TGCT cis rs704 0.628 rs10853128 chr17:26721304 A/G cg10342447 chr17:26645325 TMEM97 -0.46 -4.63 -0.38 9.04e-6 Osteoprotegerin levels; TGCT cis rs7811142 1.000 rs7809801 chr7:100072031 T/C cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.94 7.92 0.58 1.17e-12 Platelet count; TGCT trans rs2727020 0.513 rs10839307 chr11:49609843 A/C cg15704280 chr7:45808275 SEPT13 -0.72 -8.6 -0.61 2.91e-14 Coronary artery disease; TGCT cis rs6542838 0.583 rs12712040 chr2:99513416 C/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.51 -4.71 -0.39 6.41e-6 Fear of minor pain; TGCT cis rs8037137 0.915 rs8028409 chr15:91506422 A/T cg22570213 chr15:91497863 RCCD1 0.52 4.87 0.4 3.29e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs887829 0.569 rs10179091 chr2:234657983 A/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.5 -0.37 1.56e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs6450176 1.000 rs3776707 chr5:53304873 T/C ch.5.1024479R chr5:53302184 ARL15 -0.49 -4.6 -0.38 1.03e-5 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs2980439 0.846 rs2980437 chr8:8094763 C/T cg08975724 chr8:8085496 FLJ10661 -0.54 -5.26 -0.43 6.02e-7 Neuroticism; TGCT cis rs9916302 0.851 rs11078906 chr17:37662767 C/T cg15445000 chr17:37608096 MED1 0.31 4.59 0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs7937682 0.889 rs3017767 chr11:111508098 A/G cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs9383153 0.590 rs2072736 chr6:16328068 T/C cg10975897 chr6:15504844 JARID2 0.8 4.45 0.37 1.88e-5 Gambling; TGCT cis rs586688 1.000 rs522869 chr1:201638600 A/G cg05779441 chr1:201574716 NA 0.29 4.81 0.4 4.25e-6 Obesity-related traits; TGCT cis rs651907 0.640 rs771574 chr3:101620682 A/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.59 5.6 0.45 1.34e-7 Colorectal cancer; TGCT cis rs10464366 0.517 rs13231075 chr7:39174806 G/T cg18850127 chr7:39170497 POU6F2 0.33 7.18 0.54 5.5e-11 IgG glycosylation; TGCT cis rs3785574 0.962 rs16947051 chr17:61790917 G/C cg06601766 chr17:61851465 DDX42;CCDC47 0.59 5.3 0.43 5.06e-7 Height; TGCT cis rs72781680 1.000 rs56205282 chr2:24221317 C/T cg08917208 chr2:24149416 ATAD2B 0.82 4.92 0.4 2.68e-6 Lymphocyte counts; TGCT cis rs4803468 1.000 rs878083 chr19:41897688 G/A cg09537434 chr19:41945824 ATP5SL -0.89 -9.84 -0.66 3.15e-17 Height; TGCT cis rs17443541 0.507 rs4675699 chr2:200451389 A/C cg00055341 chr2:200446845 NA -0.31 -4.45 -0.37 1.89e-5 Intelligence (multi-trait analysis); TGCT cis rs4919044 0.641 rs11187225 chr10:94714427 C/G cg05127821 chr10:94822908 CYP26C1 -0.73 -4.47 -0.37 1.74e-5 Coronary artery disease; TGCT cis rs1062177 0.547 rs2915818 chr5:151115290 T/A cg00977110 chr5:151150581 G3BP1 -0.41 -4.89 -0.4 3.1e-6 Preschool internalizing problems; TGCT cis rs16867321 1.000 rs1358521 chr2:181444628 T/C cg23363182 chr2:181467187 NA -0.39 -5.47 -0.44 2.38e-7 Obesity; TGCT cis rs28595532 0.688 rs116566508 chr4:119619195 G/A cg21605333 chr4:119757512 SEC24D 1.33 8.02 0.58 6.93e-13 Cannabis dependence symptom count; TGCT cis rs67311347 1.000 rs1466236 chr3:40462162 C/T cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs2594989 1.000 rs2594994 chr3:11339960 T/A cg00170343 chr3:11313890 ATG7 0.67 5.06 0.41 1.44e-6 Circulating chemerin levels; TGCT cis rs259282 0.519 rs259276 chr19:33160953 C/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 1.0 10.18 0.67 4.62e-18 Schizophrenia; TGCT cis rs7845219 0.544 rs4570121 chr8:95917088 C/T cg16049864 chr8:95962084 TP53INP1 -0.48 -5.3 -0.43 5.23e-7 Type 2 diabetes; TGCT cis rs10032931 0.962 rs1385670 chr4:96456167 T/A cg03008707 chr4:96468962 UNC5C -0.33 -4.72 -0.39 6.35e-6 Optic nerve measurement (cup-to-disc ratio); TGCT cis rs1348850 0.567 rs880898 chr2:178532470 C/T cg22681709 chr2:178499509 PDE11A -0.48 -6.02 -0.48 1.81e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs4654899 1.000 rs7521675 chr1:21424070 T/C cg01072550 chr1:21505969 NA -0.48 -7.71 -0.57 3.44e-12 Superior frontal gyrus grey matter volume; TGCT cis rs1371867 0.846 rs959022 chr8:101295992 T/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT trans rs1814175 0.715 rs1722007 chr11:49897319 T/C cg11707556 chr5:10655725 ANKRD33B -0.37 -7.34 -0.55 2.4e-11 Height; TGCT cis rs2019137 0.539 rs4849177 chr2:113982584 T/C cg06675538 chr2:114033490 PAX8;LOC440839 -0.42 -4.65 -0.39 8.23e-6 Lymphocyte counts; TGCT cis rs12142240 0.738 rs67545510 chr1:46806242 G/T cg14993813 chr1:46806288 NSUN4 -0.58 -4.78 -0.39 4.78e-6 Menopause (age at onset); TGCT cis rs7552404 0.924 rs1146579 chr1:76209792 C/T cg22875332 chr1:76189707 ACADM -0.72 -9.0 -0.63 3.21e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6089829 0.962 rs6011548 chr20:61666063 C/T cg02380750 chr20:61661411 NA 0.35 6.1 0.48 1.25e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs7085104 0.700 rs743572 chr10:104597152 A/G cg15744005 chr10:104629667 AS3MT -0.42 -5.28 -0.43 5.69e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs180358 0.738 rs180323 chr11:116626570 A/G cg08672956 chr11:116640933 BUD13 -0.22 -4.49 -0.37 1.6e-5 Multiple sclerosis (severity); TGCT cis rs7582180 0.585 rs6736311 chr2:100950599 C/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.95 -0.41 2.34e-6 Intelligence (multi-trait analysis); TGCT cis rs8111998 0.826 rs59838183 chr19:22766434 G/A cg19914732 chr19:22715077 NA -0.56 -4.51 -0.38 1.46e-5 Corneal structure; TGCT cis rs9549367 0.713 rs1755690 chr13:113824266 T/C cg18105134 chr13:113819100 PROZ 0.48 8.52 0.61 4.55e-14 Platelet distribution width; TGCT cis rs2153535 0.580 rs9505450 chr6:8469902 C/T cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs9300255 0.537 rs10772993 chr12:123644714 A/G cg00376283 chr12:123451042 ABCB9 0.72 4.96 0.41 2.29e-6 Neutrophil percentage of white cells; TGCT cis rs2075371 0.796 rs12154724 chr7:133943443 G/A cg11752832 chr7:134001865 SLC35B4 0.66 5.51 0.44 1.95e-7 Mean platelet volume; TGCT cis rs12643440 0.538 rs2314599 chr4:17139624 A/G cg22650099 chr4:17144496 NA -0.48 -4.75 -0.39 5.59e-6 Metabolite levels (Pyroglutamine); TGCT trans rs10504390 0.585 rs79812520 chr8:66507615 T/C cg07799219 chr22:43901523 MPPED1 -0.71 -6.88 -0.53 2.67e-10 IgG glycosylation; TGCT cis rs769267 0.930 rs1865034 chr19:19605763 C/T cg20644253 chr19:19431407 KIAA0892;SF4 0.68 5.62 0.45 1.18e-7 Tonsillectomy; TGCT cis rs7666738 0.830 rs10050008 chr4:99025313 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs57221529 0.709 rs72703090 chr5:598314 C/T cg09021430 chr5:549028 NA -0.43 -5.77 -0.46 5.99e-8 Lung disease severity in cystic fibrosis; TGCT cis rs9486719 1.000 rs2499807 chr6:96864053 T/G cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs6688613 0.840 rs6699294 chr1:166955174 G/A cg07049167 chr1:166818506 POGK 0.26 5.18 0.42 8.56e-7 Refractive astigmatism; TGCT trans rs11088226 0.681 rs2833901 chr21:33939318 T/C cg09050820 chr6:167586206 TCP10L2 0.79 7.04 0.53 1.13e-10 Gastritis; TGCT cis rs896854 0.573 rs11996455 chr8:95853708 G/A cg16049864 chr8:95962084 TP53INP1 -0.6 -7.11 -0.54 8.27e-11 Type 2 diabetes; TGCT cis rs68170813 0.559 rs6965001 chr7:106933196 A/G cg02696742 chr7:106810147 HBP1 -0.69 -5.81 -0.46 4.85e-8 Coronary artery disease; TGCT cis rs7260538 0.808 rs2086785 chr19:41527085 T/C cg20630647 chr19:41531805 NA 0.31 4.93 0.4 2.58e-6 DDT metabolite (p,p'-DDE levels); TGCT cis rs597539 0.690 rs608810 chr11:68624118 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.86 7.61 0.56 5.94e-12 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6684514 1.000 rs10908502 chr1:156300082 A/G cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6951245 1.000 rs74366004 chr7:1088630 A/C cg23708337 chr7:1209742 NA 0.56 5.08 0.42 1.34e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9486719 1.000 rs2472886 chr6:96864876 C/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7572733 0.515 rs11891555 chr2:198853540 G/T cg00792783 chr2:198669748 PLCL1 0.57 5.09 0.42 1.29e-6 Dermatomyositis; TGCT trans rs877282 0.898 rs11253350 chr10:765968 G/A cg22713356 chr15:30763199 NA 1.2 9.39 0.64 3.76e-16 Uric acid levels; TGCT cis rs6952808 0.636 rs73048162 chr7:1949328 T/C cg22963979 chr7:1858916 MAD1L1 -0.36 -5.49 -0.44 2.18e-7 Bipolar disorder and schizophrenia; TGCT cis rs9894429 1.000 rs11652797 chr17:79574124 A/G cg18240062 chr17:79603768 NPLOC4 0.67 6.84 0.52 3.23e-10 Eye color traits; TGCT cis rs4285028 0.580 rs1523519 chr3:121631841 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.63 -5.37 -0.43 3.74e-7 Multiple sclerosis; TGCT cis rs2071303 1.000 rs2071303 chr6:26091336 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.61 -5.83 -0.46 4.55e-8 Intelligence (multi-trait analysis); TGCT cis rs7336332 0.598 rs77055070 chr13:28010516 C/G cg22138327 chr13:27999177 GTF3A 0.8 5.97 0.47 2.35e-8 Weight; TGCT cis rs7523273 0.606 rs761275 chr1:207972154 A/C cg22525895 chr1:207977042 MIR29B2 -0.52 -8.83 -0.62 8.51e-15 Schizophrenia; TGCT cis rs478304 0.934 rs669742 chr11:65501291 C/T cg27068330 chr11:65405492 SIPA1 0.75 7.39 0.55 1.93e-11 Acne (severe); TGCT cis rs2228479 0.717 rs11644967 chr16:89806614 T/A cg26513180 chr16:89883248 FANCA 0.79 4.57 0.38 1.16e-5 Skin colour saturation; TGCT cis rs634534 0.622 rs624273 chr11:65712413 A/G cg17985854 chr11:65770987 BANF1;EIF1AD 0.21 4.58 0.38 1.12e-5 Sum eosinophil basophil counts;Eosinophil counts; TGCT cis rs11578119 0.832 rs10919376 chr1:170350049 T/G cg09767346 chr1:170501363 GORAB 0.61 4.57 0.38 1.16e-5 Male-pattern baldness; TGCT cis rs6450176 0.638 rs56220547 chr5:53287952 A/G ch.5.1024479R chr5:53302184 ARL15 -0.77 -5.46 -0.44 2.46e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs4285028 0.747 rs3732410 chr3:121415720 T/C cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.3 -0.55 3.03e-11 Multiple sclerosis; TGCT cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg24549020 chr5:56110836 MAP3K1 0.75 6.06 0.48 1.52e-8 Initial pursuit acceleration; TGCT cis rs338419 1.000 rs900630 chr15:60512695 C/T cg03365496 chr15:60286384 NA -0.4 -4.48 -0.37 1.66e-5 Blood protein levels; TGCT cis rs3806843 0.576 rs251368 chr5:140241027 G/T cg09824255 chr5:140014002 CD14 -0.27 -4.68 -0.39 7.25e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs8177253 0.965 rs4854760 chr3:133498741 C/T cg01448562 chr3:133502909 NA 0.34 6.81 0.52 3.73e-10 Iron status biomarkers; TGCT cis rs4853012 0.793 rs6707619 chr2:74344656 G/A cg01017244 chr2:74357527 NA 0.51 8.97 0.63 3.95e-15 Gestational age at birth (maternal effect); TGCT trans rs9467711 1.000 rs34569761 chr6:26334306 A/G cg20516262 chr7:155325649 CNPY1 0.56 6.89 0.53 2.46e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs8072100 0.840 rs4968319 chr17:45464967 A/G cg08085267 chr17:45401833 C17orf57 -0.47 -5.56 -0.45 1.57e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs12134245 0.776 rs13447464 chr1:91968278 G/A cg07090678 chr1:91966139 CDC7 0.36 4.9 0.4 2.92e-6 Breast cancer; TGCT cis rs7465272 0.515 rs34087536 chr8:143720876 G/A cg24634471 chr8:143751801 JRK 0.53 5.11 0.42 1.18e-6 Bipolar disorder and schizophrenia; TGCT cis rs611744 0.901 rs599357 chr8:109194160 T/C cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs12220238 0.822 rs10824160 chr10:76132267 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.17 0.48 9.08e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs950169 1.000 rs12903820 chr15:84723820 A/G cg17173187 chr15:85201210 NMB 0.47 5.23 0.42 7.11e-7 Schizophrenia; TGCT cis rs2243480 0.908 rs1532573 chr7:65798802 A/G cg20637647 chr7:64974828 NA -0.92 -5.09 -0.42 1.26e-6 Diabetic kidney disease; TGCT cis rs11096990 0.613 rs4974990 chr4:39193265 T/C cg20847110 chr4:39482781 LOC401127 0.16 4.52 0.38 1.42e-5 Cognitive function; TGCT cis rs1887596 0.705 rs9788361 chr13:27201814 A/G cg01312412 chr13:27282625 NA 0.3 5.31 0.43 4.89e-7 Facial morphology (factor 3, length of philtrum); TGCT cis rs2235642 0.826 rs8048410 chr16:1614097 A/G cg08296037 chr16:1584118 IFT140;TMEM204 -0.31 -5.22 -0.42 7.31e-7 Coronary artery disease; TGCT cis rs7772486 0.686 rs1011596 chr6:146076433 A/G cg23711669 chr6:146136114 FBXO30 0.88 9.38 0.64 4.01e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs4478858 0.735 rs6676682 chr1:31809816 C/T cg00250761 chr1:31883323 NA -0.28 -4.96 -0.41 2.32e-6 Alcohol dependence; TGCT cis rs7772486 0.558 rs7753273 chr6:146066039 C/T cg05347473 chr6:146136440 FBXO30 -0.68 -6.22 -0.49 7.01e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs2797160 0.651 rs1269176 chr6:126029682 A/T cg05901451 chr6:126070800 HEY2 -0.72 -6.47 -0.5 2.08e-9 Endometrial cancer; TGCT cis rs1723838 0.826 rs1792197 chr11:73585860 G/A cg18195628 chr11:73498948 MRPL48 0.93 4.55 0.38 1.28e-5 Obesity-related traits; TGCT cis rs2836974 0.931 rs2836968 chr21:40642386 A/G cg11890956 chr21:40555474 PSMG1 1.1 12.16 0.74 7.11e-23 Cognitive function; TGCT cis rs13242816 1.000 rs17138747 chr7:116132670 G/A cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs10791097 0.667 rs4937584 chr11:130741761 A/G cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs67311347 1.000 rs1466237 chr3:40462026 C/G cg13683864 chr3:40499215 RPL14 -1.02 -10.48 -0.69 8.69e-19 Renal cell carcinoma; TGCT cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg10802521 chr3:52805072 NEK4 -0.71 -8.79 -0.62 1.04e-14 Bipolar disorder; TGCT cis rs950027 0.620 rs1153857 chr15:45659095 G/T cg14582100 chr15:45693742 SPATA5L1 0.47 6.02 0.48 1.8e-8 Response to fenofibrate (adiponectin levels); TGCT cis rs7666738 0.830 rs10001701 chr4:98918871 G/C cg17366294 chr4:99064904 C4orf37 0.71 7.25 0.55 3.96e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2028201 0.900 rs2289196 chr2:201305086 A/G cg04781494 chr2:202047246 CASP10 0.24 4.51 0.38 1.46e-5 Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis; TGCT cis rs2836974 0.897 rs2836928 chr21:40543320 C/T cg06238570 chr21:40685208 BRWD1 0.62 5.42 0.44 2.97e-7 Cognitive function; TGCT cis rs35146811 0.735 rs1727133 chr7:99812870 C/T cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs2739330 0.615 rs2858911 chr22:24297195 G/T cg10150615 chr22:24372951 LOC391322 -0.97 -12.67 -0.75 4.14e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs617219 0.737 rs1275103 chr5:78448105 C/G cg23987322 chr5:78407566 BHMT 0.36 4.82 0.4 4.19e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6430585 0.646 rs12468768 chr2:136494985 C/T cg07169764 chr2:136633963 MCM6 1.21 11.31 0.71 8.06e-21 Corneal structure; TGCT cis rs7043114 0.507 rs10761154 chr9:95144086 A/G cg14631576 chr9:95140430 CENPP -0.27 -4.56 -0.38 1.22e-5 Height; TGCT cis rs4665809 1.000 rs750451 chr2:26324241 G/A cg25036284 chr2:26402008 FAM59B -0.54 -4.7 -0.39 6.93e-6 Gut microbiome composition (summer); TGCT cis rs453301 0.686 rs10217044 chr8:8894752 A/G cg00184457 chr8:8946301 NA -0.26 -4.94 -0.41 2.43e-6 Joint mobility (Beighton score); TGCT trans rs28595532 0.557 rs7696047 chr4:119303024 G/A cg26518628 chr1:97050305 NA -0.53 -7.44 -0.56 1.48e-11 Cannabis dependence symptom count; TGCT cis rs2204008 0.774 rs8189620 chr12:38241621 A/G cg13010199 chr12:38710504 ALG10B 0.64 5.01 0.41 1.85e-6 Bladder cancer; TGCT cis rs4478858 0.662 rs6425735 chr1:31783945 T/C cg00250761 chr1:31883323 NA -0.27 -4.94 -0.41 2.43e-6 Alcohol dependence; TGCT cis rs28386778 0.863 rs7221573 chr17:61859390 G/A cg11494091 chr17:61959527 GH2 0.61 14.8 0.8 3.65e-29 Prudent dietary pattern; TGCT cis rs9640161 0.789 rs28439010 chr7:150046276 C/T cg17279839 chr7:150038598 RARRES2 0.43 4.64 0.38 8.89e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs13064411 0.542 rs2399477 chr3:113222998 A/G cg18753928 chr3:113234510 CCDC52 -0.56 -4.72 -0.39 6.3e-6 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7824557 0.614 rs10503421 chr8:11221313 C/T cg21775007 chr8:11205619 TDH 0.72 6.59 0.51 1.11e-9 Retinal vascular caliber; TGCT cis rs4839421 0.934 rs12046828 chr1:111017477 C/G cg06880108 chr1:111021908 CYMP 0.18 5.42 0.44 2.96e-7 Response to bupropion in depression; TGCT trans rs877282 0.947 rs957642 chr10:773966 C/T cg22713356 chr15:30763199 NA 1.11 9.86 0.66 2.79e-17 Uric acid levels; TGCT cis rs9733 0.519 rs1336899 chr1:150678910 T/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs1483890 1.000 rs900671 chr3:69406527 C/A cg22125112 chr3:69402811 FRMD4B 0.27 4.52 0.38 1.45e-5 Resting heart rate; TGCT cis rs1371867 0.839 rs1660313 chr8:101332712 G/A cg06636551 chr8:101224915 SPAG1 -0.48 -6.52 -0.51 1.62e-9 Atrioventricular conduction; TGCT cis rs1552244 0.872 rs6803517 chr3:10065426 C/T cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.34 0.55 2.43e-11 Prudent dietary pattern; TGCT cis rs910316 0.967 rs35446981 chr14:75637351 A/T cg08847533 chr14:75593920 NEK9 -0.92 -9.96 -0.67 1.6e-17 Height; TGCT cis rs4819052 0.851 rs8126930 chr21:46671715 A/G cg02159808 chr21:46707872 POFUT2;LOC642852 0.55 4.48 0.37 1.66e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs4665809 0.590 rs17528590 chr2:26505858 A/G cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs4808199 0.793 rs12459676 chr19:19425141 A/T cg03709012 chr19:19516395 GATAD2A 0.77 5.36 0.43 3.99e-7 Nonalcoholic fatty liver disease; TGCT cis rs6121246 0.559 rs10439607 chr20:30258541 G/A cg10886678 chr20:30946050 ASXL1 -0.52 -4.44 -0.37 1.97e-5 Mean corpuscular hemoglobin; TGCT cis rs28386778 0.863 rs9897229 chr17:61782325 T/C cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.96 0.41 2.22e-6 Prudent dietary pattern; TGCT cis rs6690583 0.623 rs55721024 chr1:85454447 A/C cg20280350 chr1:85513789 MCOLN3 -0.74 -5.11 -0.42 1.2e-6 Serum sulfate level; TGCT cis rs151997 1.000 rs27247 chr5:50232299 T/C cg06027927 chr5:50259733 NA -0.47 -4.86 -0.4 3.47e-6 Callous-unemotional behaviour; TGCT trans rs7618501 0.699 rs1317154 chr3:49910084 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.9 9.84 0.66 3.04e-17 Intelligence (multi-trait analysis); TGCT cis rs612683 0.824 rs17454919 chr1:100830370 A/G cg06223162 chr1:101003688 GPR88 0.29 4.99 0.41 1.97e-6 Breast cancer; TGCT cis rs10479542 0.701 rs10479541 chr5:178981003 G/C cg11939631 chr5:178977406 RUFY1 0.48 4.58 0.38 1.1e-5 Lung cancer; TGCT cis rs17384381 1.000 rs12129502 chr1:85900727 T/C cg16011679 chr1:85725395 C1orf52 0.82 6.67 0.51 7.53e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs6952808 0.723 rs4721287 chr7:2028663 A/C cg04267008 chr7:1944627 MAD1L1 -0.41 -5.45 -0.44 2.65e-7 Bipolar disorder and schizophrenia; TGCT cis rs4820539 1.000 rs885965 chr22:23461425 A/G cg21100191 chr22:23484243 RTDR1 0.95 11.16 0.71 1.87e-20 Bone mineral density; TGCT cis rs7412746 0.611 rs7532045 chr1:150821847 G/A cg04414720 chr1:150670196 GOLPH3L 0.38 4.62 0.38 9.47e-6 Melanoma; TGCT cis rs7666738 0.830 rs62321569 chr4:98984250 T/A cg18180107 chr4:99064573 C4orf37 0.55 5.07 0.41 1.43e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1971762 0.583 rs11170648 chr12:54089660 C/T cg16917193 chr12:54089295 NA 1.34 17.42 0.84 4.03e-35 Height; TGCT cis rs10883723 0.773 rs2296587 chr10:104245588 G/A cg05855489 chr10:104503620 C10orf26 -0.54 -4.44 -0.37 1.99e-5 Allergic disease (asthma, hay fever or eczema); TGCT cis rs911263 0.961 rs8008961 chr14:68752643 A/G cg18825221 chr14:68749962 RAD51L1 0.28 5.33 0.43 4.4e-7 Primary biliary cholangitis; TGCT cis rs9995821 0.591 rs35148853 chr4:154819521 A/G cg00381131 chr4:154073616 TRIM2 -0.66 -4.6 -0.38 1.02e-5 facial morphology traits (multivariate analysis); TGCT cis rs9993613 0.875 rs60645723 chr4:73484862 G/A cg15102770 chr4:73434591 ADAMTS3 0.52 4.89 0.4 3.12e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs57920188 0.584 rs10915654 chr1:4091419 C/A cg20703997 chr1:4087676 NA 0.49 5.75 0.46 6.45e-8 Interleukin-17 levels; TGCT cis rs35883536 0.611 rs61070860 chr1:101097628 G/A cg06223162 chr1:101003688 GPR88 0.32 5.34 0.43 4.31e-7 Monocyte count; TGCT cis rs1371867 0.875 rs1619759 chr8:101337560 T/C cg06636551 chr8:101224915 SPAG1 -0.49 -6.59 -0.51 1.12e-9 Atrioventricular conduction; TGCT cis rs9300255 0.602 rs1727317 chr12:123618942 T/C cg00376283 chr12:123451042 ABCB9 0.72 4.96 0.41 2.31e-6 Neutrophil percentage of white cells; TGCT cis rs9611565 0.659 rs9607812 chr22:41941243 G/A cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs4319547 0.656 rs10846664 chr12:122823777 C/T cg08088222 chr12:122070432 ORAI1 -0.27 -4.77 -0.39 5.11e-6 Body mass index; TGCT cis rs2243480 0.522 rs778717 chr7:65848151 G/C cg20637647 chr7:64974828 NA 0.93 5.08 0.42 1.34e-6 Diabetic kidney disease; TGCT cis rs12483853 1.000 rs12483853 chr22:40539525 G/C cg07138101 chr22:40742427 ADSL 0.77 5.5 0.44 2.12e-7 Breast cancer; TGCT cis rs889312 0.500 rs185219 chr5:56136492 A/G cg24531977 chr5:56204891 C5orf35 -0.52 -5.39 -0.44 3.44e-7 Breast cancer;Breast cancer (early onset); TGCT cis rs587847 0.737 rs4924156 chr15:37688630 G/A cg00216138 chr15:37171175 LOC145845 0.31 4.5 0.37 1.52e-5 Intraocular pressure; TGCT cis rs35146811 0.659 rs863450 chr7:99821685 C/T cg22906224 chr7:99728672 NA -0.5 -4.51 -0.38 1.48e-5 Coronary artery disease; TGCT cis rs59107033 0.607 rs62262427 chr3:123125779 A/G cg04890266 chr3:123102914 ADCY5 -0.37 -5.59 -0.45 1.39e-7 Lymphocyte counts; TGCT cis rs4722166 0.695 rs7787893 chr7:22774437 A/G cg26061582 chr7:22766209 IL6 0.55 7.08 0.54 9.23e-11 Lung cancer; TGCT cis rs2836950 0.501 rs13047518 chr21:40707307 G/A cg06238570 chr21:40685208 BRWD1 -0.64 -6.51 -0.5 1.71e-9 Menarche (age at onset); TGCT cis rs11098499 0.908 rs28499576 chr4:120386677 G/A cg09307838 chr4:120376055 NA 0.71 6.96 0.53 1.71e-10 Corneal astigmatism; TGCT cis rs61884328 0.777 rs61897776 chr11:47133419 C/G cg13308137 chr11:47528955 CUGBP1 0.38 4.47 0.37 1.76e-5 Total body bone mineral density (age over 60); TGCT cis rs4727027 0.933 rs12540094 chr7:148847178 A/G cg23583168 chr7:148888333 NA 0.77 9.82 0.66 3.39e-17 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs10504229 1.000 rs67243305 chr8:58174958 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs10892173 0.566 rs10892175 chr11:117674355 G/A cg07621104 chr11:117668040 DSCAML1 0.74 8.12 0.59 3.98e-13 Myopia; TGCT trans rs901683 0.702 rs73292848 chr10:46169752 T/C cg24926042 chr12:52799999 KRT82 -0.61 -6.62 -0.51 9.55e-10 Red blood cell traits;Mean corpuscular volume; TGCT cis rs12142240 0.698 rs10158130 chr1:46822600 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs6840360 0.642 rs2724571 chr4:152376795 T/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.83e-9 Intelligence (multi-trait analysis); TGCT cis rs853679 0.517 rs9468297 chr6:28118874 G/T cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs644799 0.965 rs2950522 chr11:95524719 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7119038 0.818 rs7942535 chr11:118681464 C/T cg19308663 chr11:118741387 NA -0.28 -5.74 -0.46 6.95e-8 Sjögren's syndrome; TGCT cis rs9457247 1.000 rs405553 chr6:167395058 A/G cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs2777491 0.957 rs16971798 chr15:41657144 A/T cg18705301 chr15:41695430 NDUFAF1 0.72 10.08 0.67 8.2e-18 Ulcerative colitis; TGCT cis rs7666738 0.830 rs13130923 chr4:99046281 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.26e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg12419862 chr22:24373484 LOC391322 -0.84 -9.42 -0.65 3.27e-16 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs5769707 0.935 rs1109320 chr22:49989106 G/A cg05373962 chr22:49881684 NA -0.3 -6.11 -0.48 1.17e-8 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7811142 0.830 rs73401450 chr7:99981859 G/C cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.99 -8.64 -0.61 2.39e-14 Platelet count; TGCT cis rs12210905 0.688 rs72845012 chr6:27501986 C/A cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg15242686 chr22:24348715 GSTTP1 0.44 6.09 0.48 1.3e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9383153 1.000 rs9370887 chr6:16329258 G/C cg23850913 chr6:15505452 JARID2 0.85 4.68 0.39 7.32e-6 Gambling; TGCT cis rs748404 0.660 rs690512 chr15:43717678 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs763014 0.966 rs7198877 chr16:661439 A/G cg09263875 chr16:632152 PIGQ 0.31 6.76 0.52 4.93e-10 Height; TGCT cis rs2739330 0.828 rs4820572 chr22:24250355 T/C cg10150615 chr22:24372951 LOC391322 -1.0 -13.02 -0.76 5.83e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs732765 0.734 rs12891243 chr14:75208656 G/A cg06637938 chr14:75390232 RPS6KL1 -0.56 -4.87 -0.4 3.28e-6 Non-small cell lung cancer; TGCT cis rs7830933 0.955 rs7835797 chr8:23597020 A/G cg04349084 chr8:23602677 NA 0.24 4.88 0.4 3.24e-6 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs4819052 0.765 rs2838852 chr21:46677037 C/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.81 7.17 0.54 5.96e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs1129187 0.702 rs2296805 chr6:42928758 T/G cg27588902 chr6:42928151 GNMT -0.59 -7.2 -0.54 5.01e-11 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs2797160 0.522 rs6925158 chr6:125940188 T/G cg05901451 chr6:126070800 HEY2 -0.64 -5.37 -0.43 3.67e-7 Endometrial cancer; TGCT cis rs9325144 0.647 rs11168819 chr12:39011082 C/A cg26384229 chr12:38710491 ALG10B -0.58 -5.49 -0.44 2.16e-7 Morning vs. evening chronotype; TGCT cis rs1153858 1.000 rs1153849 chr15:45695695 G/A cg26924012 chr15:45694286 SPATA5L1 0.99 12.38 0.74 2.11e-23 Homoarginine levels; TGCT cis rs10782582 0.522 rs12125933 chr1:76130920 C/T cg22875332 chr1:76189707 ACADM -0.55 -6.27 -0.49 5.53e-9 Daytime sleep phenotypes; TGCT cis rs12478296 1.000 rs55758933 chr2:243040289 T/C cg06360820 chr2:242988706 NA -0.61 -4.66 -0.39 8.13e-6 Obesity-related traits; TGCT cis rs9914544 0.545 rs9898426 chr17:18794071 A/G cg26378065 chr17:18585709 ZNF286B 0.53 4.63 0.38 9.01e-6 Educational attainment (years of education); TGCT cis rs12477438 0.798 rs6716913 chr2:99580641 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.72 -6.25 -0.49 5.98e-9 Chronic sinus infection; TGCT cis rs2153535 0.580 rs6941771 chr6:8494452 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs62244186 0.715 rs13321717 chr3:44667455 C/A cg15687855 chr3:44754131 ZNF502 -0.46 -5.56 -0.45 1.58e-7 Depressive symptoms; TGCT cis rs2836974 0.831 rs34294410 chr21:40555160 C/G cg06238570 chr21:40685208 BRWD1 0.75 7.06 0.54 1.07e-10 Cognitive function; TGCT cis rs8072100 0.738 rs9915222 chr17:45448615 G/T cg08085267 chr17:45401833 C17orf57 -0.51 -5.6 -0.45 1.3e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs2544523 0.511 rs2544535 chr2:15906778 A/G cg26669897 chr2:15909070 NA 0.38 5.06 0.41 1.48e-6 Asthma or chronic obstructive pulmonary disease; TGCT cis rs28595532 0.920 rs116305850 chr4:119779892 A/G cg11846333 chr4:119757529 SEC24D 0.92 4.64 0.38 8.74e-6 Cannabis dependence symptom count; TGCT cis rs611744 0.967 rs673015 chr8:109191669 C/T cg21045802 chr8:109455806 TTC35 0.5 4.62 0.38 9.35e-6 Dupuytren's disease; TGCT cis rs12497850 0.931 rs13064911 chr3:48952385 A/G cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs2153535 0.580 rs9379216 chr6:8481235 G/A cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs881375 0.933 rs4837799 chr9:123668326 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.45 4.94 0.41 2.44e-6 Rheumatoid arthritis; TGCT trans rs12599106 0.629 rs1391904 chr16:34548934 C/T cg11235426 chr6:292522 DUSP22 -0.66 -6.87 -0.53 2.76e-10 Menopause (age at onset); TGCT trans rs8073060 0.586 rs7213804 chr17:34010931 T/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT trans rs12655019 0.920 rs1466007 chr5:56213639 A/C cg25190722 chr1:3801660 DFFB 0.62 7.17 0.54 5.87e-11 Breast cancer (early onset); TGCT cis rs9486715 0.929 rs7775721 chr6:97056979 C/T cg18709589 chr6:96969512 KIAA0776 -0.87 -8.44 -0.6 7.09e-14 Headache; TGCT cis rs4631830 0.965 rs4306255 chr10:51542444 A/G cg10326726 chr10:51549505 MSMB -0.25 -4.94 -0.41 2.52e-6 Prostate-specific antigen levels; TGCT cis rs7914558 0.901 rs35525740 chr10:104941112 A/T cg04362960 chr10:104952993 NT5C2 0.61 5.45 0.44 2.6e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs2115630 0.967 rs10438428 chr15:85330745 C/T cg11189052 chr15:85197271 WDR73 -0.63 -6.19 -0.49 8.12e-9 P wave terminal force; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg14893161 chr1:205819251 PM20D1 0.68 11.2 0.71 1.56e-20 Menarche (age at onset); TGCT cis rs66573146 1.000 rs7686186 chr4:6986094 C/T cg01220768 chr4:7056774 TADA2B 0.39 4.91 0.4 2.77e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs28595532 0.920 rs115530096 chr4:119760512 T/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs907683 0.635 rs11691617 chr2:220295167 C/T cg15015639 chr2:220282977 DES 0.37 4.72 0.39 6.3e-6 Resting heart rate; TGCT cis rs514406 0.861 rs35581164 chr1:53271373 C/G cg22166914 chr1:53195759 ZYG11B 0.41 7.23 0.54 4.29e-11 Monocyte count; TGCT cis rs7772486 0.754 rs697053 chr6:145989807 T/C cg13319975 chr6:146136371 FBXO30 0.56 5.03 0.41 1.7e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs12762955 0.561 rs1904671 chr10:1014603 G/A cg20503657 chr10:835505 NA -0.39 -5.04 -0.41 1.58e-6 Response to angiotensin II receptor blocker therapy; TGCT cis rs2180341 0.855 rs9385422 chr6:127716457 C/T cg27446573 chr6:127587934 RNF146 0.92 8.5 0.61 5.15e-14 Breast cancer; TGCT cis rs12711979 0.509 rs10195488 chr2:3824135 T/C cg17052675 chr2:3827356 NA -0.55 -12.73 -0.75 2.94e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7178572 0.568 rs12916731 chr15:77507021 C/T cg15453836 chr15:77711506 NA -0.43 -4.82 -0.4 4.12e-6 Type 2 diabetes; TGCT cis rs9814567 0.722 rs13083717 chr3:134348796 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.74 5.4 0.44 3.22e-7 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs28386778 0.897 rs2665795 chr17:61925272 A/G cg06896619 chr17:61851486 DDX42;CCDC47 0.51 4.96 0.41 2.24e-6 Prudent dietary pattern; TGCT cis rs9914988 0.887 rs12948575 chr17:27130520 G/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs10504229 0.679 rs17804870 chr8:58158071 A/G cg20607798 chr8:58055168 NA 0.57 4.57 0.38 1.19e-5 Developmental language disorder (linguistic errors); TGCT cis rs793571 0.544 rs1427282 chr15:58914326 C/T cg05156742 chr15:59063176 FAM63B 0.56 5.31 0.43 4.95e-7 Schizophrenia; TGCT cis rs36051895 0.664 rs3780373 chr9:5098223 T/C cg02405213 chr9:5042618 JAK2 -0.76 -10.67 -0.69 3.05e-19 Pediatric autoimmune diseases; TGCT cis rs17152411 1.000 rs733402 chr10:126594152 T/C cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs2739330 0.828 rs2330635 chr22:24251344 T/C cg15242686 chr22:24348715 GSTTP1 0.43 5.78 0.46 5.8e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4824093 0.610 rs7410534 chr22:50289925 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.5 5.17 0.42 9.25e-7 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs514406 0.929 rs1672909 chr1:53340824 A/G cg16325326 chr1:53192061 ZYG11B 0.61 6.79 0.52 4.18e-10 Monocyte count; TGCT cis rs9549260 0.709 rs9549247 chr13:41220777 G/C cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs548181 0.611 rs1293672 chr11:125461034 A/G cg03464685 chr11:125439445 EI24 1.37 9.3 0.64 6.08e-16 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4654899 0.802 rs10493004 chr1:21442736 T/C cg01072550 chr1:21505969 NA -0.47 -7.02 -0.53 1.27e-10 Superior frontal gyrus grey matter volume; TGCT cis rs9660992 0.674 rs1151784 chr1:205232447 C/T cg00857998 chr1:205179979 DSTYK 0.52 4.56 0.38 1.19e-5 Mean corpuscular volume;Mean platelet volume; TGCT cis rs597539 0.652 rs569777 chr11:68706848 G/A cg04772025 chr11:68637568 NA 0.62 6.89 0.53 2.52e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs514406 0.929 rs483073 chr1:53314084 T/C cg08859206 chr1:53392774 SCP2 -0.41 -6.39 -0.5 3.01e-9 Monocyte count; TGCT cis rs10193935 0.901 rs59984817 chr2:42566909 C/G cg27598129 chr2:42591480 NA -0.41 -5.66 -0.45 1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10197940 0.578 rs2444264 chr2:152310928 G/T cg19508488 chr2:152266495 RIF1 -0.51 -4.47 -0.37 1.74e-5 Lung cancer; TGCT trans rs28735056 0.967 rs4799092 chr18:77608203 C/G cg05926928 chr17:57297772 GDPD1 -0.71 -7.57 -0.56 7.48e-12 Schizophrenia; TGCT cis rs7618915 0.501 rs2336146 chr3:52626646 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs7714584 1.000 rs11741861 chr5:150277909 C/T cg22134413 chr5:150180641 NA -1.14 -8.32 -0.6 1.33e-13 Crohn's disease; TGCT cis rs707040 0.881 rs7575231 chr2:155228406 G/A cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg18538332 chr22:24372958 LOC391322 -1.01 -12.77 -0.75 2.33e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs4252435 0.614 rs4252417 chr7:142625258 G/A cg09833174 chr7:143059591 FAM131B -1.04 -4.97 -0.41 2.17e-6 Cancer; TGCT cis rs1371867 0.846 rs1660349 chr8:101319326 G/A cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs9611565 0.918 rs4820438 chr22:41767135 C/T cg13695892 chr22:41940480 POLR3H -0.86 -8.08 -0.59 4.85e-13 Vitiligo; TGCT cis rs77140172 0.677 rs28435799 chr4:89617931 G/A cg01026744 chr4:89619053 NAP1L5;HERC3 1.28 5.48 0.44 2.32e-7 Post bronchodilator FEV1; TGCT cis rs11578119 0.902 rs12138138 chr1:170420921 C/T cg09767346 chr1:170501363 GORAB 0.71 5.65 0.45 1.04e-7 Male-pattern baldness; TGCT cis rs477895 1.000 rs477895 chr11:64048912 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 -0.66 -5.08 -0.41 1.37e-6 Mean platelet volume; TGCT trans rs7618501 0.633 rs6771546 chr3:49968572 T/C cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.4 0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs7100689 0.646 rs1538815 chr10:82137670 A/G cg01528321 chr10:82214614 TSPAN14 0.8 7.72 0.57 3.42e-12 Post bronchodilator FEV1; TGCT cis rs7833790 0.963 rs1451997 chr8:82774053 A/T cg27398817 chr8:82754497 SNX16 0.84 6.3 0.49 4.81e-9 Diastolic blood pressure; TGCT cis rs6704768 0.545 rs5004510 chr2:233679275 A/C cg08000102 chr2:233561755 GIGYF2 -0.69 -7.77 -0.57 2.62e-12 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs950169 0.580 rs36126054 chr15:85177723 T/G cg12863693 chr15:85201151 NMB 0.46 5.56 0.45 1.6e-7 Schizophrenia; TGCT cis rs514406 0.760 rs1242198 chr1:53352016 G/A cg08859206 chr1:53392774 SCP2 -0.44 -6.85 -0.52 3.1e-10 Monocyte count; TGCT cis rs344364 0.511 rs12599337 chr16:1946751 A/G cg26617929 chr16:1858877 NA 0.28 4.98 0.41 2.11e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs7829975 0.502 rs7820738 chr8:8702607 C/G cg06636001 chr8:8085503 FLJ10661 -0.74 -7.09 -0.54 9.14e-11 Mood instability; TGCT cis rs9611565 0.722 rs202635 chr22:41809637 C/T cg03806693 chr22:41940476 POLR3H 1.01 11.44 0.72 3.94e-21 Vitiligo; TGCT cis rs394563 0.717 rs548848 chr6:149782009 A/G cg16235748 chr6:149772707 ZC3H12D -0.42 -4.67 -0.39 7.79e-6 Dupuytren's disease; TGCT cis rs854765 0.693 rs4924822 chr17:17748013 A/G cg04398451 chr17:18023971 MYO15A 0.31 4.66 0.39 7.97e-6 Total body bone mineral density; TGCT cis rs2836974 0.544 rs8128919 chr21:40711862 C/T cg11890956 chr21:40555474 PSMG1 0.78 7.85 0.58 1.65e-12 Cognitive function; TGCT cis rs1062177 1.000 rs2915887 chr5:151205504 C/T cg00977110 chr5:151150581 G3BP1 0.4 4.52 0.38 1.4e-5 Preschool internalizing problems; TGCT cis rs7772486 0.754 rs9373475 chr6:146126419 C/T cg23711669 chr6:146136114 FBXO30 0.94 10.68 0.69 2.77e-19 Lobe attachment (rater-scored or self-reported); TGCT cis rs6088590 0.561 rs6059918 chr20:33150503 C/T cg08999081 chr20:33150536 PIGU 0.28 5.42 0.44 3.02e-7 Coronary artery disease; TGCT cis rs704 0.628 rs2239911 chr17:26723613 G/T cg10342447 chr17:26645325 TMEM97 -0.45 -4.46 -0.37 1.8e-5 Osteoprotegerin levels; TGCT cis rs2153535 0.504 rs9405393 chr6:8467432 G/T cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs4819052 0.851 rs7281263 chr21:46695606 T/C cg06618935 chr21:46677482 NA -0.36 -5.61 -0.45 1.25e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs6570726 0.846 rs1935616 chr6:145943512 C/T cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs9653442 0.576 rs6542921 chr2:100864498 C/A cg22139774 chr2:100720529 AFF3 -0.39 -6.4 -0.5 2.93e-9 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3849570 0.615 rs35779564 chr3:81982771 G/A cg07356753 chr3:81810745 GBE1 -0.69 -6.36 -0.5 3.55e-9 Waist circumference;Body mass index; TGCT cis rs858239 0.698 rs4265084 chr7:23407240 G/C cg05602783 chr7:23145260 KLHL7 -0.71 -5.95 -0.47 2.53e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs3087591 0.821 rs12949024 chr17:29445086 A/T cg24425628 chr17:29625626 OMG;NF1 0.49 7.37 0.55 2.15e-11 Hip circumference; TGCT cis rs7089973 0.624 rs10885614 chr10:116609098 C/T cg03647239 chr10:116582469 FAM160B1 0.59 5.74 0.46 6.72e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs709400 0.663 rs3742458 chr14:103950368 A/G cg26031613 chr14:104095156 KLC1 0.84 9.5 0.65 2.08e-16 Body mass index; TGCT cis rs1129187 0.755 rs28868299 chr6:42921221 T/G cg09436375 chr6:42928200 GNMT -0.4 -5.19 -0.42 8.34e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs10779751 0.770 rs1148480 chr1:11172006 A/G cg08854313 chr1:11322531 MTOR 0.83 8.02 0.58 6.7e-13 Body mass index; TGCT cis rs9583531 0.600 rs4773240 chr13:111360585 G/A cg24331049 chr13:111365604 ING1 0.76 7.31 0.55 2.95e-11 Coronary artery disease; TGCT cis rs9611565 0.802 rs73176692 chr22:41785735 G/A cg06481639 chr22:41940642 POLR3H -0.61 -5.49 -0.44 2.17e-7 Vitiligo; TGCT cis rs12541335 0.603 rs9792127 chr8:22180334 G/A cg07298985 chr8:22133076 PIWIL2 0.33 5.32 0.43 4.73e-7 Hypertriglyceridemia; TGCT cis rs7714584 1.000 rs73282209 chr5:150174959 G/A cg22134413 chr5:150180641 NA 1.17 8.69 0.62 1.76e-14 Crohn's disease; TGCT cis rs3096299 0.719 rs2911262 chr16:89515041 C/T cg06640241 chr16:89574553 SPG7 0.73 7.86 0.58 1.61e-12 Multiple myeloma (IgH translocation); TGCT cis rs9611565 0.918 rs28638318 chr22:41753059 G/A cg06481639 chr22:41940642 POLR3H -0.72 -6.33 -0.49 4.05e-9 Vitiligo; TGCT cis rs7647973 0.626 rs4855833 chr3:49657441 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs35160687 0.842 rs1863051 chr2:86559148 A/C cg03171300 chr2:86307199 POLR1A 0.26 4.57 0.38 1.14e-5 Night sleep phenotypes; TGCT cis rs6964587 0.869 rs4729010 chr7:91486751 G/A cg17063962 chr7:91808500 NA -0.85 -9.05 -0.63 2.54e-15 Breast cancer; TGCT cis rs9894429 0.869 rs9748184 chr17:79596280 A/G cg18240062 chr17:79603768 NPLOC4 0.69 7.22 0.54 4.67e-11 Eye color traits; TGCT cis rs9486719 0.947 rs12194971 chr6:96911073 T/C cg06623918 chr6:96969491 KIAA0776 -1.01 -8.77 -0.62 1.18e-14 Migraine;Coronary artery disease; TGCT cis rs6740322 0.748 rs6720087 chr2:43468745 A/G cg06169590 chr2:43455088 ZFP36L2;LOC100129726 0.4 6.1 0.48 1.25e-8 Coronary artery disease; TGCT cis rs6089584 0.962 rs6142913 chr20:60566950 A/G cg13770153 chr20:60521292 NA -0.47 -5.99 -0.47 2.13e-8 Body mass index; TGCT cis rs17376456 0.877 rs17316137 chr5:93456577 C/T cg25358565 chr5:93447407 FAM172A 0.92 8.38 0.6 9.58e-14 Diabetic retinopathy; TGCT cis rs7586879 0.639 rs2033656 chr2:25100902 C/G cg01884057 chr2:25150051 NA 0.33 6.31 0.49 4.6e-9 Body mass index; TGCT cis rs9660180 0.868 rs12567685 chr1:1806647 T/C cg23982607 chr1:1823379 GNB1 -0.55 -8.48 -0.61 5.58e-14 Body mass index; TGCT cis rs10782582 0.609 rs5745347 chr1:76274520 C/T cg10523679 chr1:76189770 ACADM 0.57 5.29 0.43 5.27e-7 Daytime sleep phenotypes; TGCT cis rs11122272 0.735 rs2808597 chr1:231532351 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.53 -0.51 1.55e-9 Hemoglobin concentration; TGCT cis rs7715806 0.500 rs2291630 chr5:75013356 G/A cg19683494 chr5:74908142 NA 0.56 4.86 0.4 3.41e-6 Body mass index in physically active individuals;Body mass index;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs3858526 0.651 rs10838713 chr11:5858434 T/C cg13902645 chr11:5959945 NA -0.42 -4.57 -0.38 1.18e-5 DNA methylation (variation); TGCT trans rs28595532 0.623 rs56324414 chr4:119274655 A/C cg26518628 chr1:97050305 NA -0.6 -7.07 -0.54 1.01e-10 Cannabis dependence symptom count; TGCT cis rs3008870 1.000 rs12740884 chr1:67459855 C/A cg11518657 chr1:67396239 MIER1 -0.54 -4.61 -0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs1903068 0.819 rs10517343 chr4:56002267 T/A cg16572876 chr4:56024045 NA 0.43 4.94 0.41 2.43e-6 Endometriosis; TGCT cis rs7760949 0.963 rs1571565 chr6:13907185 A/G cg27413430 chr6:13925136 RNF182 0.5 4.71 0.39 6.62e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs17331151 0.541 rs4687676 chr3:52890418 C/T cg15956490 chr3:53032818 SFMBT1 -0.46 -5.65 -0.45 1.05e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs394563 0.589 rs1900300 chr6:149641627 T/C cg16235748 chr6:149772707 ZC3H12D 0.43 4.98 0.41 2.05e-6 Dupuytren's disease; TGCT cis rs61935443 0.720 rs11107776 chr12:95294283 T/G cg21533806 chr12:95267307 NA 0.54 4.67 0.39 7.66e-6 Schizophrenia; TGCT cis rs7666738 0.546 rs2098935 chr4:98914376 A/G cg17366294 chr4:99064904 C4orf37 0.64 5.88 0.47 3.54e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs367943 0.644 rs348942 chr5:112824039 T/C cg12552261 chr5:112820674 MCC -0.23 -4.68 -0.39 7.45e-6 Type 2 diabetes; TGCT cis rs4711350 1.000 rs4711350 chr6:33741716 A/G cg13859433 chr6:33739653 LEMD2 -0.31 -4.5 -0.37 1.52e-5 Schizophrenia; TGCT trans rs7618501 0.602 rs2071207 chr3:50159844 T/C cg21659725 chr3:3221576 CRBN -0.73 -8.48 -0.61 5.64e-14 Intelligence (multi-trait analysis); TGCT cis rs28735056 0.592 rs12455965 chr18:77688830 G/C cg20368463 chr18:77673604 PQLC1 -0.47 -5.52 -0.44 1.86e-7 Schizophrenia; TGCT cis rs7727544 0.716 rs7720230 chr5:131592405 T/G cg24060327 chr5:131705240 SLC22A5 -0.56 -5.45 -0.44 2.62e-7 Blood metabolite levels; TGCT cis rs7582180 0.676 rs11680660 chr2:100931738 G/C cg08017756 chr2:100939284 LONRF2 -0.3 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.659 rs72701605 chr9:5062056 G/A cg02405213 chr9:5042618 JAK2 -0.73 -9.89 -0.66 2.38e-17 Pediatric autoimmune diseases; TGCT cis rs2243480 1.000 rs10950032 chr7:65738591 C/A cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs921968 0.541 rs561570 chr2:219379348 T/A cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs523522 0.962 rs10849759 chr12:120994488 T/A cg27279351 chr12:120934652 DYNLL1 0.74 6.46 0.5 2.19e-9 High light scatter reticulocyte count; TGCT cis rs3096299 0.967 rs2965827 chr16:89457350 A/C cg02187348 chr16:89574699 SPG7 -0.49 -4.53 -0.38 1.36e-5 Multiple myeloma (IgH translocation); TGCT cis rs7568458 0.905 rs10187424 chr2:85794297 T/C cg17127132 chr2:85788382 GGCX 0.73 6.97 0.53 1.64e-10 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6121246 0.567 rs6060295 chr20:30198473 C/T cg13852791 chr20:30311386 BCL2L1 0.7 4.58 0.38 1.1e-5 Mean corpuscular hemoglobin; TGCT cis rs1982963 0.639 rs2749875 chr14:52503396 G/A cg10843707 chr14:52510701 NID2 -0.36 -7.22 -0.54 4.54e-11 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1150668 0.799 rs1150707 chr6:28197605 C/T cg11262757 chr6:27280423 POM121L2 0.45 4.44 0.37 1.94e-5 Pubertal anthropometrics; TGCT cis rs4727027 0.870 rs11524138 chr7:148799125 G/A cg23583168 chr7:148888333 NA -0.72 -9.11 -0.63 1.8e-15 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs2549003 1.000 rs2549009 chr5:131826765 T/C cg21138405 chr5:131827807 IRF1 -0.18 -4.46 -0.37 1.82e-5 Asthma (sex interaction); TGCT cis rs4664308 0.875 rs60908067 chr2:161004983 T/G cg03641300 chr2:160917029 PLA2R1 -0.27 -6.74 -0.52 5.42e-10 Idiopathic membranous nephropathy; TGCT cis rs62380364 0.602 rs11743441 chr5:88065637 G/T cg22951263 chr5:87985283 NA -0.6 -6.35 -0.5 3.73e-9 Intelligence (multi-trait analysis); TGCT cis rs2303745 0.589 rs1864115 chr19:17393327 G/C cg02221750 chr19:17393354 ANKLE1 -0.48 -6.27 -0.49 5.46e-9 Systemic lupus erythematosus; TGCT trans rs57221529 0.664 rs72704802 chr5:554211 C/T cg11887960 chr12:57824829 NA 1.12 8.84 0.62 7.84e-15 Lung disease severity in cystic fibrosis; TGCT cis rs10504229 1.000 rs67895971 chr8:58177994 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs2204008 0.837 rs12369089 chr12:38060263 G/A cg13010199 chr12:38710504 ALG10B 0.65 5.29 0.43 5.47e-7 Bladder cancer; TGCT cis rs11190604 1.000 rs9420797 chr10:102331147 C/T cg23241863 chr10:102295624 HIF1AN 0.69 5.21 0.42 7.71e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg19045956 chr2:200819837 C2orf60;C2orf47 0.55 5.88 0.47 3.6e-8 Osteoporosis; TGCT cis rs7246657 0.722 rs2927739 chr19:38149330 C/A cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs2836974 0.863 rs12483216 chr21:40539614 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.49 0.65 2.19e-16 Cognitive function; TGCT cis rs17433780 0.836 rs17434342 chr1:89505742 C/G cg09516651 chr1:89888402 LOC400759 -0.25 -4.66 -0.39 8.01e-6 Carotid intima media thickness; TGCT cis rs4383453 0.510 rs16834219 chr3:123099470 A/G cg04890266 chr3:123102914 ADCY5 -0.5 -8.34 -0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs9297145 0.678 rs62473051 chr7:98781955 C/T cg05967295 chr7:98741636 SMURF1 0.99 12.22 0.74 4.99e-23 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs7582180 0.764 rs11682748 chr2:100925934 C/A cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs7917772 0.582 rs3936017 chr10:104354424 T/C cg11453585 chr10:104263688 ACTR1A;SUFU 0.55 5.36 0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1348850 0.567 rs3770009 chr2:178536544 C/T cg22681709 chr2:178499509 PDE11A -0.46 -5.73 -0.46 7.14e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs78545713 1.000 rs77281308 chr6:26250029 C/T cg10570941 chr6:26273029 HIST1H3G;HIST1H2BI -0.71 -4.68 -0.39 7.39e-6 Iron status biomarkers (total iron binding capacity); TGCT cis rs7020830 0.825 rs7036132 chr9:37317241 A/G cg14294708 chr9:37120828 ZCCHC7 1.27 17.5 0.84 2.7e-35 Schizophrenia; TGCT cis rs8177253 0.965 rs8177245 chr3:133479230 A/G cg08048268 chr3:133502702 NA -0.66 -9.83 -0.66 3.36e-17 Iron status biomarkers; TGCT cis rs7714584 1.000 rs60134818 chr5:150261043 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT trans rs10506458 0.915 rs2013042 chr12:63394211 A/G cg22491629 chr6:157744540 C6orf35 -0.96 -8.31 -0.6 1.42e-13 Hemostatic factors and hematological phenotypes; TGCT trans rs1496653 0.602 rs71322202 chr3:23623852 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs5769707 0.872 rs5770604 chr22:50030672 G/A cg20744362 chr22:50050164 C22orf34 0.29 4.61 0.38 9.85e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs13217239 0.646 rs10946897 chr6:26995251 A/C cg15659132 chr6:26577336 NA 0.54 5.44 0.44 2.78e-7 Schizophrenia; TGCT cis rs11249608 0.548 rs12152869 chr5:178462520 A/G cg01312482 chr5:178451176 ZNF879 -0.49 -4.83 -0.4 3.96e-6 Pubertal anthropometrics; TGCT cis rs9911578 0.835 rs9303398 chr17:56484257 T/C cg12560992 chr17:57184187 TRIM37 -0.78 -9.12 -0.63 1.72e-15 Intelligence (multi-trait analysis); TGCT cis rs5750830 0.649 rs5757659 chr22:39812409 A/C cg02038168 chr22:39784481 NA -0.7 -5.72 -0.46 7.48e-8 Intelligence (multi-trait analysis); TGCT cis rs17253792 0.822 rs76612185 chr14:56037706 T/C cg01858014 chr14:56050164 KTN1 -0.36 -4.57 -0.38 1.15e-5 Putamen volume; TGCT cis rs7412746 0.658 rs2864869 chr1:150734655 G/A cg09365446 chr1:150670422 GOLPH3L 0.35 5.08 0.42 1.33e-6 Melanoma; TGCT trans rs561341 0.882 rs16967101 chr17:30377162 A/G cg20587970 chr11:113659929 NA -0.96 -12.55 -0.75 7.96e-24 Hip circumference adjusted for BMI; TGCT cis rs1401999 1.000 rs1533684 chr3:183635815 A/G cg01324343 chr3:183735012 ABCC5 0.85 11.47 0.72 3.33e-21 Anterior chamber depth; TGCT cis rs6095298 0.574 rs67843835 chr20:47453760 G/A cg12307787 chr20:48099359 KCNB1 0.42 4.51 0.38 1.51e-5 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs13101352 chr4:98957544 C/T cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs394563 0.591 rs237028 chr6:149718650 C/T cg03678062 chr6:149772716 ZC3H12D -0.38 -4.74 -0.39 5.87e-6 Dupuytren's disease; TGCT cis rs3772130 0.962 rs13433692 chr3:121484714 G/T cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs3849570 0.961 rs3772912 chr3:81698481 A/G cg07356753 chr3:81810745 GBE1 -0.69 -6.02 -0.48 1.81e-8 Waist circumference;Body mass index; TGCT cis rs7769051 1.000 rs7769051 chr6:133146796 G/T cg22852734 chr6:133119734 C6orf192 1.29 7.34 0.55 2.44e-11 Type 2 diabetes nephropathy; TGCT trans rs11250098 0.583 rs73196860 chr8:10814133 A/G cg06636001 chr8:8085503 FLJ10661 -0.81 -7.26 -0.55 3.71e-11 Morning vs. evening chronotype; TGCT cis rs17711722 0.701 rs781143 chr7:65439879 G/C cg18876405 chr7:65276391 NA 0.38 5.89 0.47 3.4e-8 Calcium levels; TGCT trans rs916888 0.773 rs199451 chr17:44801784 G/A cg10053473 chr17:62856997 LRRC37A3 -0.47 -6.69 -0.51 7.01e-10 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2243480 1.000 rs56016656 chr7:65383481 C/T cg07424592 chr7:64974309 NA 1.36 8.08 0.59 4.97e-13 Diabetic kidney disease; TGCT cis rs9913156 0.793 rs72835643 chr17:4573612 G/A cg23387401 chr17:4582204 PELP1 0.32 4.7 0.39 6.8e-6 Lymphocyte counts; TGCT cis rs6460942 0.841 rs6968277 chr7:12443795 C/A cg06484146 chr7:12443880 VWDE -0.54 -5.76 -0.46 6.25e-8 Coronary artery disease; TGCT cis rs765787 0.530 rs2554456 chr15:45521138 A/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.45 -0.44 2.66e-7 Uric acid levels; TGCT cis rs6540559 0.673 rs17015224 chr1:209968918 G/A cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT trans rs13064411 0.542 rs4396864 chr3:113212562 C/T cg00307254 chr3:126706825 PLXNA1 0.34 6.72 0.52 5.79e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7677751 0.767 rs6832597 chr4:55076237 C/A cg17187183 chr4:55093834 PDGFRA 0.47 6.33 0.49 4.12e-9 Corneal astigmatism; TGCT cis rs12893668 0.543 rs1799796 chr14:104165927 T/C cg26031613 chr14:104095156 KLC1 -0.59 -5.0 -0.41 1.94e-6 Reticulocyte count; TGCT cis rs2404602 0.735 rs11857327 chr15:76764263 G/C cg22467129 chr15:76604101 ETFA 0.48 5.11 0.42 1.16e-6 Blood metabolite levels; TGCT cis rs9611565 0.659 rs28623192 chr22:41940524 A/G cg17554472 chr22:41940697 POLR3H -0.49 -5.27 -0.43 5.9e-7 Vitiligo; TGCT cis rs35883536 0.631 rs2783704 chr1:101040652 T/A cg10298815 chr1:101004474 GPR88 0.24 4.51 0.38 1.47e-5 Monocyte count; TGCT cis rs9549260 0.753 rs9532578 chr13:41236407 G/A cg21288729 chr13:41239152 FOXO1 0.68 4.75 0.39 5.58e-6 Red blood cell count; TGCT cis rs9921338 0.887 rs9926136 chr16:11437275 A/G cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.32e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs9942416 0.660 rs17563863 chr5:74998334 G/A cg02573091 chr5:74908125 NA 0.38 4.51 0.38 1.47e-5 Age-related disease endophenotypes; TGCT cis rs12142240 0.698 rs6429599 chr1:46827871 G/A cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs35883536 0.647 rs2809795 chr1:101038345 A/G cg06223162 chr1:101003688 GPR88 0.43 8.24 0.59 2.07e-13 Monocyte count; TGCT cis rs2841277 0.509 rs11850949 chr14:105408827 A/C cg19901468 chr14:105411992 AHNAK2 -0.27 -5.57 -0.45 1.53e-7 Rheumatoid arthritis; TGCT cis rs12136530 0.593 rs12121242 chr1:19740609 G/C cg24875000 chr1:19041556 PAX7 -0.26 -4.62 -0.38 9.56e-6 Lead levels in blood; TGCT cis rs9372498 0.536 rs9489436 chr6:118873817 A/C cg21191810 chr6:118973309 C6orf204 -0.37 -4.83 -0.4 4.03e-6 Diastolic blood pressure; TGCT cis rs10504229 0.906 rs114810777 chr8:58185298 A/G cg08280861 chr8:58055591 NA 0.37 4.99 0.41 1.95e-6 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.962 rs11932892 chr4:99072967 C/T cg17366294 chr4:99064904 C4orf37 0.85 7.29 0.55 3.19e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs873946 0.648 rs12766166 chr10:134556403 G/C cg27286337 chr10:134555280 INPP5A 0.39 4.68 0.39 7.36e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4073582 0.595 rs1115508 chr11:65923149 A/G cg16950941 chr11:66035639 RAB1B 0.53 5.08 0.42 1.34e-6 Gout; TGCT cis rs12142240 0.698 rs66483119 chr1:46838389 T/C cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs4455778 0.659 rs1004168 chr7:49030320 C/A cg26309511 chr7:48887640 NA 0.44 5.22 0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs1008375 0.863 rs4590022 chr4:17614434 T/C cg10189774 chr4:17578691 LAP3 0.65 5.49 0.44 2.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.897 rs35123057 chr21:40711689 C/T cg17971929 chr21:40555470 PSMG1 0.91 8.16 0.59 3.18e-13 Cognitive function; TGCT cis rs12368653 0.591 rs1038914 chr12:58011066 G/A cg12615879 chr12:58013172 SLC26A10 -0.52 -6.24 -0.49 6.47e-9 Multiple sclerosis; TGCT cis rs1532993 0.518 rs1993409 chr4:98635911 C/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.92 -0.4 2.72e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs4819052 0.851 rs7276591 chr21:46680156 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs367615 0.879 rs4351197 chr5:108866667 A/G cg17395555 chr5:108820864 NA 0.31 5.01 0.41 1.85e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs6089829 0.962 rs4809462 chr20:61661560 A/G cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg00814883 chr7:100076585 TSC22D4 -0.89 -9.24 -0.64 8.75e-16 Platelet count; TGCT cis rs1129187 0.755 rs3293 chr6:42938377 G/T cg27588902 chr6:42928151 GNMT -0.56 -6.93 -0.53 2.08e-10 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs6570726 0.599 rs4398765 chr6:145935006 C/A cg05347473 chr6:146136440 FBXO30 0.62 5.7 0.46 8.22e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs8141529 0.509 rs5762853 chr22:29245231 T/G cg02153584 chr22:29168773 CCDC117 0.6 4.84 0.4 3.81e-6 Lymphocyte counts; TGCT cis rs7944584 0.511 rs10838725 chr11:47557871 T/C cg20307385 chr11:47447363 PSMC3 0.88 8.62 0.61 2.57e-14 Fasting blood glucose;Fasting blood glucose (BMI interaction); TGCT cis rs17253792 0.822 rs10083431 chr14:56068348 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs2440129 0.632 rs15966 chr17:6905643 T/C cg03407747 chr17:6899364 ALOX12 0.54 5.85 0.47 4.06e-8 Tonsillectomy; TGCT cis rs28386778 0.897 rs2584601 chr17:61940977 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.31 0.43 4.95e-7 Prudent dietary pattern; TGCT cis rs13191362 1.000 rs13210756 chr6:163009030 T/A cg21926612 chr6:163149169 PACRG;PARK2 0.68 5.79 0.46 5.33e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs78487399 0.808 rs6544664 chr2:43729108 T/A cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.74 4.49 0.37 1.59e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs60843830 0.661 rs62116681 chr2:104197 A/T cg25945732 chr2:264204 ACP1;SH3YL1 0.62 5.52 0.44 1.92e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs12765878 0.812 rs7076119 chr10:105667110 T/C cg11005552 chr10:105648138 OBFC1 -0.44 -7.3 -0.55 3.08e-11 Coronary artery disease; TGCT cis rs6088580 0.634 rs6088483 chr20:32984714 T/A cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs10504229 1.000 rs79311869 chr8:58195546 T/C cg21724239 chr8:58056113 NA 0.38 4.76 0.39 5.41e-6 Developmental language disorder (linguistic errors); TGCT cis rs6912958 0.712 rs7746465 chr6:88348996 T/G cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.98 -0.41 2.06e-6 Monocyte percentage of white cells; TGCT cis rs6448317 0.539 rs13113895 chr4:24932077 T/C cg21108841 chr4:24914750 CCDC149 -0.75 -7.11 -0.54 8.21e-11 Heschl's gyrus morphology; TGCT cis rs13108904 0.870 rs4974541 chr4:1244037 A/G cg13395646 chr4:1353034 KIAA1530 -0.36 -4.77 -0.39 5.17e-6 Obesity-related traits; TGCT cis rs35146811 0.735 rs2528900 chr7:99805319 A/G cg22906224 chr7:99728672 NA -0.49 -4.45 -0.37 1.88e-5 Coronary artery disease; TGCT cis rs7000551 0.725 rs2249098 chr8:22400098 T/C cg12081754 chr8:22256438 SLC39A14 0.28 4.69 0.39 6.95e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9296092 0.500 rs4376348 chr6:33521097 A/G cg13560919 chr6:33536144 NA -0.2 -4.64 -0.38 8.68e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs7843479 0.965 rs3816786 chr8:21860425 A/T cg17168535 chr8:21777572 XPO7 0.63 5.78 0.46 5.59e-8 Mean corpuscular volume; TGCT cis rs17253792 0.822 rs78261053 chr14:56061784 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs12908161 0.959 rs3748376 chr15:85328352 C/T cg12863693 chr15:85201151 NMB 0.42 5.01 0.41 1.81e-6 Schizophrenia; TGCT cis rs13242816 1.000 rs12672717 chr7:116128270 G/A cg16553024 chr7:116138462 CAV2 -0.45 -5.04 -0.41 1.57e-6 P wave duration; TGCT cis rs35146811 0.735 rs11764176 chr7:99786964 G/T cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs11190604 0.943 rs11190574 chr10:102234331 T/C cg16342193 chr10:102329863 NA -0.41 -5.3 -0.43 5.06e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs2197308 0.740 rs10880619 chr12:37922720 T/C cg13010199 chr12:38710504 ALG10B 0.67 5.38 0.44 3.57e-7 Morning vs. evening chronotype; TGCT cis rs4936891 1.000 rs7119122 chr11:123917281 A/C cg22125253 chr11:123886957 OR10G4 0.21 4.59 0.38 1.07e-5 Male fertility; TGCT cis rs2022068 0.583 rs2284020 chr22:37200835 G/A cg26999345 chr22:37584441 C1QTNF6 0.2 4.47 0.37 1.77e-5 Pit-and-Fissure caries; TGCT cis rs9921222 0.597 rs7193109 chr16:413523 T/G cg00101154 chr16:420108 MRPL28 -0.62 -7.02 -0.53 1.27e-10 Bone mineral density (spine);Bone mineral density; TGCT trans rs7618501 1.000 rs7649348 chr3:49772375 G/A cg21659725 chr3:3221576 CRBN -0.98 -15.33 -0.81 2.1000000000000002e-30 Intelligence (multi-trait analysis); TGCT cis rs739496 0.895 rs7309325 chr12:111849515 G/T cg10833066 chr12:111807467 FAM109A 0.36 5.33 0.43 4.55e-7 Platelet count; TGCT cis rs951366 0.677 rs1775140 chr1:205672107 C/A cg07167872 chr1:205819463 PM20D1 0.57 6.98 0.53 1.55e-10 Menarche (age at onset); TGCT cis rs4319547 0.656 rs7294559 chr12:122837564 C/A cg08088222 chr12:122070432 ORAI1 0.26 4.59 0.38 1.09e-5 Body mass index; TGCT cis rs2295359 1.000 rs4655682 chr1:67610967 C/T cg03340356 chr1:67600835 NA 0.37 4.5 0.38 1.51e-5 Psoriasis; TGCT cis rs7267979 0.966 rs2482923 chr20:25308981 T/C cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs909674 0.818 rs7364148 chr22:39842165 T/C cg02038168 chr22:39784481 NA -0.74 -5.74 -0.46 7.01e-8 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs2153535 0.541 rs945304 chr6:8442892 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs12902680 0.739 rs1607720 chr15:46419082 T/A cg13605988 chr15:45421612 DUOX1;DUOXA1 0.33 4.62 0.38 9.28e-6 Neuroticism; TGCT cis rs7826238 0.535 rs2979179 chr8:8320029 C/T cg15556689 chr8:8085844 FLJ10661 0.7 6.35 0.5 3.69e-9 Systolic blood pressure; TGCT cis rs6693567 0.545 rs12049177 chr1:150474337 G/A cg09579323 chr1:150459698 TARS2 0.53 4.63 0.38 9.01e-6 Migraine; TGCT cis rs12900413 0.603 rs7177841 chr15:90302117 C/A cg24249390 chr15:90295951 MESP1 -0.3 -5.2 -0.42 8.04e-7 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs7226408 0.857 rs72887016 chr18:34464090 G/T cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg16325326 chr1:53192061 ZYG11B 0.61 6.97 0.53 1.66e-10 Monocyte count; TGCT cis rs78456975 0.550 rs10197874 chr2:1545310 A/G cg01028140 chr2:1542097 TPO -0.34 -4.85 -0.4 3.68e-6 Placebo response in major depressive disorder (% change in symptom score); TGCT cis rs10504229 0.953 rs59265461 chr8:58189701 A/T cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs1801251 1.000 rs1044480 chr2:233633736 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.45 0.5 2.22e-9 Coronary artery disease; TGCT cis rs11098499 0.779 rs10857066 chr4:120286596 C/T cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs765787 0.530 rs1706832 chr15:45517173 C/T cg24006582 chr15:45444508 DUOX1 -0.24 -5.28 -0.43 5.49e-7 Uric acid levels; TGCT cis rs9640161 0.830 rs12703061 chr7:150062545 T/C cg10018233 chr7:150070692 REPIN1 0.31 4.73 0.39 6.11e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs7772486 0.764 rs2247211 chr6:146216379 G/A cg05347473 chr6:146136440 FBXO30 0.5 4.9 0.4 2.94e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2153535 0.580 rs9378556 chr6:8514695 A/G cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs1799949 1.000 rs8176103 chr17:41267050 G/A cg10047753 chr17:41438598 NA 0.92 9.49 0.65 2.12e-16 Menopause (age at onset); TGCT cis rs9611565 0.685 rs169363 chr22:41853117 G/T cg17554472 chr22:41940697 POLR3H 0.48 4.97 0.41 2.16e-6 Vitiligo; TGCT cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg04317338 chr11:64019027 PLCB3 0.78 6.46 0.5 2.17e-9 Mean platelet volume; TGCT cis rs2836974 0.590 rs11911822 chr21:40607843 C/T cg11890956 chr21:40555474 PSMG1 -0.79 -7.77 -0.57 2.51e-12 Cognitive function; TGCT cis rs7267979 0.527 rs6083891 chr20:25574272 C/G cg03522245 chr20:25566470 NINL -0.44 -4.59 -0.38 1.06e-5 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7216064 0.734 rs12942774 chr17:65967562 A/G cg12091567 chr17:66097778 LOC651250 0.64 5.31 0.43 4.81e-7 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs9902453 0.967 rs61014003 chr17:28485233 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.51 0.5 1.66e-9 Coffee consumption (cups per day); TGCT cis rs2072499 0.966 rs2842857 chr1:156168736 T/C cg25208724 chr1:156163844 SLC25A44 1.14 17.15 0.84 1.56e-34 Testicular germ cell tumor; TGCT cis rs7246657 0.941 rs7256130 chr19:37933981 T/C cg18154014 chr19:37997991 ZNF793 0.73 5.38 0.44 3.53e-7 Coronary artery calcification; TGCT cis rs1322512 0.761 rs1631293 chr6:152939886 T/C cg03415253 chr6:152958462 SYNE1 -0.54 -5.01 -0.41 1.83e-6 Tonometry; TGCT cis rs617791 0.530 rs10791835 chr11:65750924 C/A cg09783858 chr11:65769428 EIF1AD;BANF1 0.5 4.56 0.38 1.2e-5 Breast cancer; TGCT cis rs12643440 0.538 rs2041442 chr4:17137895 C/T cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 8.14e-6 Metabolite levels (Pyroglutamine); TGCT cis rs295140 0.605 rs3739119 chr2:201194279 C/A cg04283868 chr2:201171347 SPATS2L 0.48 4.59 0.38 1.07e-5 QT interval; TGCT cis rs62244186 0.659 rs12489887 chr3:44547124 A/T cg25151919 chr3:44754333 ZNF502 -0.39 -4.55 -0.38 1.26e-5 Depressive symptoms; TGCT trans rs9467711 1.000 rs9467708 chr6:26327956 T/C cg20516262 chr7:155325649 CNPY1 0.54 6.63 0.51 9.34e-10 Autism spectrum disorder or schizophrenia; TGCT cis rs9549367 0.713 rs9549682 chr13:113830181 C/T cg18105134 chr13:113819100 PROZ -0.47 -8.24 -0.59 2.05e-13 Platelet distribution width; TGCT cis rs782590 0.818 rs2627765 chr2:55883317 G/T cg03859395 chr2:55845619 SMEK2 0.81 8.13 0.59 3.82e-13 Metabolic syndrome; TGCT cis rs377070 0.966 rs411043 chr4:123633221 G/C cg10495464 chr4:123653540 BBS12;LOC729338 0.49 5.42 0.44 2.96e-7 Mosquito bite size; TGCT cis rs2066819 1.000 rs808919 chr12:56647911 C/G cg26714650 chr12:56694279 CS 1.48 8.4 0.6 8.92e-14 Psoriasis vulgaris; TGCT cis rs7584330 0.657 rs10202599 chr2:238352465 A/C cg14458575 chr2:238380390 NA 0.51 7.37 0.55 2.15e-11 Prostate cancer; TGCT cis rs2243480 0.901 rs778730 chr7:65823325 T/A cg20637647 chr7:64974828 NA 0.92 5.09 0.42 1.31e-6 Diabetic kidney disease; TGCT cis rs2549003 0.811 rs10072700 chr5:131816903 A/C cg00255919 chr5:131827918 IRF1 0.25 5.4 0.44 3.25e-7 Asthma (sex interaction); TGCT cis rs36051895 0.593 rs62541903 chr9:5146952 G/C cg02405213 chr9:5042618 JAK2 -0.7 -9.44 -0.65 2.87e-16 Pediatric autoimmune diseases; TGCT cis rs12579753 0.719 rs11115060 chr12:82269624 C/T cg07988820 chr12:82153109 PPFIA2 -0.42 -4.44 -0.37 1.97e-5 Resting heart rate; TGCT cis rs950169 0.922 rs67804993 chr15:85104030 T/G cg11189052 chr15:85197271 WDR73 0.81 6.71 0.52 6.33e-10 Schizophrenia; TGCT cis rs1878931 0.559 rs2106863 chr16:3391330 T/C cg26668626 chr16:3451006 ZNF174;ZNF434 0.79 7.61 0.56 5.86e-12 Body mass index (adult); TGCT cis rs2836974 0.897 rs8132568 chr21:40527916 C/T cg11890956 chr21:40555474 PSMG1 1.12 12.59 0.75 6.25e-24 Cognitive function; TGCT cis rs7246967 0.673 rs59567211 chr19:22829882 G/A cg05241461 chr19:22816980 ZNF492 0.66 4.44 0.37 1.95e-5 Bronchopulmonary dysplasia; TGCT cis rs13256369 0.756 rs13280759 chr8:8562995 G/T cg18904891 chr8:8559673 CLDN23 0.58 5.4 0.44 3.23e-7 Obesity-related traits; TGCT cis rs17384381 0.953 rs2076699 chr1:85817295 G/A cg16011679 chr1:85725395 C1orf52 0.87 6.78 0.52 4.43e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs7523273 0.564 rs7543097 chr1:207882592 T/G cg22525895 chr1:207977042 MIR29B2 0.29 4.48 0.37 1.69e-5 Schizophrenia; TGCT cis rs798766 0.723 rs3134865 chr4:1723279 T/C cg05874882 chr4:1763078 NA -0.36 -4.87 -0.4 3.27e-6 Bladder cancer;Urinary bladder cancer; TGCT cis rs586688 0.625 rs624041 chr1:201652769 C/G cg07139329 chr1:201708558 NAV1 -0.51 -5.18 -0.42 8.82e-7 Obesity-related traits; TGCT cis rs9309473 0.615 rs62151562 chr2:73603540 T/G cg07208825 chr2:73871855 ALMS1P 0.26 5.04 0.41 1.6e-6 Metabolite levels; TGCT cis rs9921338 0.961 rs72773825 chr16:11412448 A/G cg00044050 chr16:11439710 C16orf75 -0.93 -6.96 -0.53 1.7e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs1371867 0.846 rs1660332 chr8:101309490 A/G cg06002616 chr8:101225028 SPAG1 0.53 6.21 0.49 7.16e-9 Atrioventricular conduction; TGCT cis rs7635838 0.686 rs347588 chr3:11287504 C/T cg00170343 chr3:11313890 ATG7 0.68 6.61 0.51 1.03e-9 HDL cholesterol; TGCT cis rs17331151 0.573 rs76029595 chr3:52868523 C/T cg27565382 chr3:53032988 SFMBT1 0.47 5.96 0.47 2.42e-8 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11122272 0.735 rs2491416 chr1:231547335 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX 0.66 6.2 0.49 7.88e-9 Hemoglobin concentration; TGCT cis rs617219 0.710 rs2255913 chr5:78562399 G/C cg23987322 chr5:78407566 BHMT 0.35 4.69 0.39 7.07e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs17253792 0.731 rs8008528 chr14:56062052 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7666738 0.830 rs11097600 chr4:98959564 T/G cg18180107 chr4:99064573 C4orf37 0.55 4.98 0.41 2.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 1.000 rs8177240 chr3:133477701 T/G cg01448562 chr3:133502909 NA -0.32 -6.38 -0.5 3.17e-9 Iron status biomarkers; TGCT cis rs72781680 1.000 rs72796388 chr2:24171509 A/C cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs6674176 0.597 rs4031031 chr1:44393533 C/T cg12908607 chr1:44402522 ARTN -0.79 -9.73 -0.66 5.63e-17 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9393777 0.513 rs9295702 chr6:26634040 T/C cg15659132 chr6:26577336 NA -0.77 -5.48 -0.44 2.26e-7 Intelligence (multi-trait analysis); TGCT cis rs3749237 0.929 rs62260715 chr3:49829326 G/A cg07636037 chr3:49044803 WDR6 0.61 5.32 0.43 4.68e-7 Resting heart rate; TGCT cis rs769267 1.000 rs769267 chr19:19446936 A/G cg03709012 chr19:19516395 GATAD2A 0.7 6.0 0.47 2e-8 Tonsillectomy; TGCT cis rs9814567 1.000 rs4974484 chr3:134219019 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.96 -9.19 -0.64 1.16e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs1218582 0.711 rs4845677 chr1:154838050 C/T cg06221963 chr1:154839813 KCNN3 -0.8 -14.87 -0.8 2.38e-29 Prostate cancer; TGCT cis rs1401999 0.606 rs7644687 chr3:183753353 A/G cg01324343 chr3:183735012 ABCC5 0.75 8.76 0.62 1.25e-14 Anterior chamber depth; TGCT cis rs11785400 0.793 rs4467920 chr8:143736846 C/T cg10596483 chr8:143751796 JRK 0.54 5.44 0.44 2.7e-7 Schizophrenia; TGCT cis rs4595586 0.545 rs1839402 chr12:39371615 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs2455799 0.559 rs1447645 chr3:15930342 T/C cg12172478 chr3:16357591 RFTN1 -0.34 -4.98 -0.41 2.09e-6 Mean platelet volume; TGCT cis rs2637266 0.703 rs35654095 chr10:78472016 C/T cg18941641 chr10:78392320 NA 0.4 4.79 0.39 4.74e-6 Pulmonary function; TGCT cis rs6547741 1.000 rs6706610 chr2:27778091 G/A cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs7666738 0.962 rs4699605 chr4:99064379 A/G cg17366294 chr4:99064904 C4orf37 0.71 6.36 0.5 3.48e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs7085104 0.660 rs7902804 chr10:104585405 A/T cg04362960 chr10:104952993 NT5C2 0.58 5.08 0.42 1.35e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs597539 0.652 rs507520 chr11:68666054 C/T cg06028808 chr11:68637592 NA 0.52 6.74 0.52 5.33e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT trans rs17685 0.672 rs10952841 chr7:75778626 A/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs5750830 0.621 rs5750810 chr22:39792943 A/G cg02038168 chr22:39784481 NA -0.77 -6.32 -0.49 4.23e-9 Intelligence (multi-trait analysis); TGCT cis rs7635838 0.819 rs904474 chr3:11524648 C/G cg00170343 chr3:11313890 ATG7 0.69 6.67 0.51 7.44e-10 HDL cholesterol; TGCT cis rs12497850 0.765 rs12487580 chr3:49182932 G/A cg18654377 chr3:49208889 KLHDC8B -0.38 -4.79 -0.4 4.61e-6 Parkinson's disease; TGCT cis rs2594989 0.943 rs2454501 chr3:11500089 A/G cg00170343 chr3:11313890 ATG7 0.69 5.12 0.42 1.16e-6 Circulating chemerin levels; TGCT cis rs3812831 0.599 rs428637 chr13:114927139 T/G cg08824895 chr13:115047677 UPF3A 0.46 4.45 0.37 1.86e-5 Schizophrenia; TGCT cis rs3125734 0.633 rs12217669 chr10:63988456 A/G cg05499367 chr10:63213510 TMEM26 0.33 4.49 0.37 1.63e-5 Rheumatoid arthritis; TGCT cis rs7772486 0.686 rs1045820 chr6:145947080 C/T cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs854765 0.624 rs12938501 chr17:17737258 A/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.52 -0.38 1.42e-5 Total body bone mineral density; TGCT cis rs7833790 0.926 rs72686467 chr8:82758929 T/G cg17211192 chr8:82754475 SNX16 1.06 8.51 0.61 4.89e-14 Diastolic blood pressure; TGCT cis rs1799949 0.965 rs8176323 chr17:41195711 G/C cg23758822 chr17:41437982 NA 0.73 6.74 0.52 5.43e-10 Menopause (age at onset); TGCT cis rs916888 0.821 rs70602 chr17:44859715 T/C cg16520312 chr17:43971471 MAPT;LOC100128977 0.57 4.86 0.4 3.45e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs8135665 0.600 rs8142379 chr22:38450971 G/A cg13116946 chr22:38479732 SLC16A8 0.28 5.55 0.45 1.63e-7 Advanced age-related macular degeneration;Age-related macular degeneration; TGCT cis rs9911578 0.967 rs7214892 chr17:57065401 G/A cg12560992 chr17:57184187 TRIM37 0.8 9.64 0.65 9.47e-17 Intelligence (multi-trait analysis); TGCT trans rs561341 0.941 rs2428341 chr17:30317295 C/T cg20587970 chr11:113659929 NA -0.97 -12.38 -0.74 2.11e-23 Hip circumference adjusted for BMI; TGCT cis rs7937612 1.000 rs7933086 chr11:120269308 A/G cg24566217 chr11:120254723 ARHGEF12 0.3 5.02 0.41 1.78e-6 Intraocular pressure; TGCT cis rs4819052 0.851 rs4819049 chr21:46673086 C/G cg06618935 chr21:46677482 NA -0.37 -5.52 -0.44 1.87e-7 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10986311 0.775 rs10986324 chr9:127121825 T/C cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.72 0.39 6.23e-6 Vitiligo; TGCT cis rs3733585 0.673 rs6850143 chr4:9958924 T/C cg11266682 chr4:10021025 SLC2A9 -0.58 -7.7 -0.57 3.69e-12 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6089584 0.566 rs11699442 chr20:60623268 A/G cg06108461 chr20:60628389 TAF4 -0.43 -5.46 -0.44 2.46e-7 Body mass index; TGCT cis rs4563143 0.514 rs73030738 chr19:29312328 G/A cg14983838 chr19:29218262 NA 0.7 5.18 0.42 8.85e-7 Methadone dose in opioid dependence; TGCT cis rs240764 0.658 rs12210255 chr6:101187540 G/C cg09795085 chr6:101329169 ASCC3 -0.51 -4.51 -0.38 1.45e-5 Neuroticism; TGCT trans rs2727020 0.729 rs4980439 chr11:49342246 G/C cg03929089 chr4:120376271 NA -0.7 -7.94 -0.58 1.06e-12 Coronary artery disease; TGCT cis rs9291683 0.551 rs62295971 chr4:9978142 G/A cg00071950 chr4:10020882 SLC2A9 0.65 8.23 0.59 2.21e-13 Bone mineral density; TGCT cis rs453301 0.686 rs2409120 chr8:8882571 G/C cg15556689 chr8:8085844 FLJ10661 -0.64 -5.26 -0.43 6.24e-7 Joint mobility (Beighton score); TGCT cis rs951366 0.617 rs823080 chr1:205789282 G/A cg23034840 chr1:205782522 SLC41A1 0.57 5.29 0.43 5.24e-7 Menarche (age at onset); TGCT cis rs9467773 1.000 rs2393670 chr6:26535541 A/G cg26531700 chr6:26746687 NA 0.47 4.57 0.38 1.14e-5 Intelligence (multi-trait analysis); TGCT cis rs9818758 0.607 rs10049462 chr3:49309684 C/T cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs2204008 0.837 rs11519926 chr12:38348992 G/A cg13010199 chr12:38710504 ALG10B 0.6 4.74 0.39 5.87e-6 Bladder cancer; TGCT cis rs9814567 1.000 rs4955555 chr3:134286427 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.94 -9.18 -0.64 1.2e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4319547 0.915 rs7316734 chr12:123117425 A/G cg05707623 chr12:122985044 ZCCHC8 -0.69 -5.47 -0.44 2.39e-7 Body mass index; TGCT cis rs7552404 0.883 rs2185436 chr1:76203783 A/G cg03433033 chr1:76189801 ACADM 0.82 9.91 0.66 2.05e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs4253772 0.591 rs6520010 chr22:46721223 G/A cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.69 5.31 0.43 4.82e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs8062405 0.789 rs2106480 chr16:28537971 T/C cg09754948 chr16:28834200 ATXN2L 0.63 5.01 0.41 1.79e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs875971 0.964 rs160635 chr7:65528918 T/C cg11764359 chr7:65958608 NA 0.53 4.64 0.38 8.87e-6 Aortic root size; TGCT cis rs2762353 0.776 rs1165178 chr6:25827516 A/G cg07061783 chr6:25882402 NA -0.45 -4.82 -0.4 4.15e-6 Blood metabolite levels; TGCT cis rs849210 0.517 rs10490295 chr2:206185236 G/C cg11793701 chr2:206547163 NRP2 -0.57 -4.75 -0.39 5.62e-6 Tonsillectomy; TGCT cis rs9517302 0.665 rs3752971 chr13:99097252 G/A cg22223119 chr13:99095684 FARP1 -0.55 -6.23 -0.49 6.58e-9 Obesity-related traits; TGCT cis rs4494114 1.000 rs6674910 chr1:39357157 C/T cg25970120 chr1:39325951 RRAGC 0.6 6.28 0.49 5.26e-9 Blood protein levels; TGCT cis rs34891900 0.507 rs2008085 chr22:18204316 T/G cg19898043 chr22:18121309 BCL2L13 0.55 4.74 0.39 5.77e-6 Sum neutrophil eosinophil counts; TGCT cis rs10779751 0.960 rs12739368 chr1:11288247 T/C cg08854313 chr1:11322531 MTOR 0.96 8.74 0.62 1.37e-14 Body mass index; TGCT cis rs10504229 0.636 rs77753517 chr8:58115897 C/T cg02725872 chr8:58115012 NA -0.38 -5.16 -0.42 9.32e-7 Developmental language disorder (linguistic errors); TGCT cis rs8050907 0.661 rs17137056 chr16:4524685 G/C cg02873098 chr16:4524103 NMRAL1;HMOX2 0.53 4.57 0.38 1.15e-5 Obesity-related traits; TGCT trans rs208520 0.690 rs12202805 chr6:66703903 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 -1.0 -11.22 -0.71 1.34e-20 Exhaled nitric oxide output; TGCT cis rs11098499 0.821 rs56155624 chr4:120291026 C/G cg09307838 chr4:120376055 NA 0.56 5.35 0.43 4.05e-7 Corneal astigmatism; TGCT cis rs13256369 0.802 rs12541520 chr8:8564146 G/T cg17143192 chr8:8559678 CLDN23 0.57 5.35 0.43 4.09e-7 Obesity-related traits; TGCT cis rs644799 0.664 rs603625 chr11:95554283 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.48 0.61 5.55e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs4900538 0.963 rs1190554 chr14:102918686 T/C cg18135206 chr14:102964638 TECPR2 0.21 5.08 0.41 1.38e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7089973 0.646 rs35453961 chr10:116638166 T/C cg03647239 chr10:116582469 FAM160B1 0.58 5.28 0.43 5.7e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs7584330 0.554 rs74832280 chr2:238426625 G/A cg08992911 chr2:238395768 MLPH 0.7 4.72 0.39 6.32e-6 Prostate cancer; TGCT cis rs1580019 0.568 rs2122633 chr7:32523870 G/T cg06627557 chr7:32535165 LSM5;AVL9 1.02 10.57 0.69 5.23e-19 Cognitive ability; TGCT cis rs478607 0.749 rs61884370 chr11:64361955 T/G cg19395706 chr11:64412079 NRXN2 0.46 4.63 0.38 8.92e-6 Urate levels; TGCT cis rs344364 0.511 rs1742467 chr16:1950187 G/T cg26617929 chr16:1858877 NA -0.27 -4.9 -0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs2295359 0.824 rs12060309 chr1:67604219 T/C cg12940439 chr1:67600707 NA 0.66 6.89 0.53 2.53e-10 Psoriasis; TGCT cis rs11696845 0.604 rs1980577 chr20:43382112 A/G cg25301532 chr20:43378953 KCNK15 0.46 5.11 0.42 1.17e-6 Obesity-related traits; TGCT cis rs17767294 0.708 rs72847348 chr6:27801853 G/A cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs6967414 0.786 rs7804259 chr7:6755448 C/G cg00387323 chr7:6746715 ZNF12 0.76 4.65 0.39 8.23e-6 Hematocrit;Hemoglobin concentration; TGCT cis rs13256369 1.000 rs4841016 chr8:8572561 C/T cg18904891 chr8:8559673 CLDN23 0.62 5.67 0.45 9.47e-8 Obesity-related traits; TGCT cis rs6087771 0.642 rs6060403 chr20:30221104 C/A cg18721089 chr20:30220636 NA -0.42 -5.19 -0.42 8.31e-7 Subcortical brain region volumes;Putamen volume; TGCT cis rs9467711 0.651 rs35506517 chr6:26044864 T/C cg16898833 chr6:26189333 HIST1H4D 1.34 6.07 0.48 1.47e-8 Autism spectrum disorder or schizophrenia; TGCT cis rs1933488 0.931 rs7750498 chr6:153424055 G/A cg24028809 chr6:153414101 RGS17 0.21 4.67 0.39 7.69e-6 Prostate cancer; TGCT cis rs3791556 1.000 rs3791558 chr2:240113255 G/A cg03281426 chr2:240109471 HDAC4 0.28 4.46 0.37 1.82e-5 Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7552404 1.000 rs4949874 chr1:76161889 T/C cg22875332 chr1:76189707 ACADM 0.79 9.77 0.66 4.68e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6121246 0.954 rs73241710 chr20:30424956 G/A cg13852791 chr20:30311386 BCL2L1 0.77 5.7 0.46 8.2e-8 Mean corpuscular hemoglobin; TGCT trans rs12339966 0.653 rs7857285 chr9:11293560 C/G cg07173112 chr1:1114698 TTLL10 -0.34 -6.94 -0.53 1.89e-10 Systolic blood pressure; TGCT cis rs7833790 0.660 rs1451995 chr8:82746123 G/C cg06027949 chr8:82754900 SNX16 0.65 5.03 0.41 1.69e-6 Diastolic blood pressure; TGCT cis rs7914558 1.000 rs7914558 chr10:104775908 G/A cg15744005 chr10:104629667 AS3MT -0.4 -4.97 -0.41 2.21e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7394190 0.748 rs79936644 chr10:75545117 C/T cg07699608 chr10:75541558 CHCHD1 0.79 5.44 0.44 2.72e-7 Incident atrial fibrillation; TGCT cis rs36093844 0.898 rs11234458 chr11:85591370 A/C cg25872744 chr11:85566296 CCDC83 -0.52 -4.73 -0.39 6.09e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs7156960 0.639 rs2360983 chr14:76727099 C/T cg13981132 chr14:76734493 NA -0.37 -5.43 -0.44 2.83e-7 Acute lymphoblastic leukemia (childhood); TGCT cis rs7618915 0.547 rs3755806 chr3:52643685 C/T cg07507251 chr3:52567010 NT5DC2 -0.48 -6.95 -0.53 1.82e-10 Bipolar disorder; TGCT cis rs7666738 0.830 rs17550735 chr4:99014076 T/G cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs597539 0.652 rs660614 chr11:68659488 G/A cg21963583 chr11:68658836 MRPL21 0.37 6.14 0.48 1.03e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6456156 0.792 rs10946214 chr6:167516122 G/A cg07741184 chr6:167504864 NA 0.22 4.44 0.37 2e-5 Primary biliary cholangitis; TGCT cis rs7647973 1.000 rs7644148 chr3:49545241 G/A cg06212747 chr3:49208901 KLHDC8B -0.57 -4.56 -0.38 1.21e-5 Menarche (age at onset); TGCT cis rs739496 0.579 rs2238152 chr12:112214459 G/T cg10833066 chr12:111807467 FAM109A 0.36 4.67 0.39 7.74e-6 Platelet count; TGCT cis rs2549003 1.000 rs2070728 chr5:131819977 C/T cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.92e-6 Asthma (sex interaction); TGCT cis rs7586879 0.796 rs11684619 chr2:25078859 G/A cg01884057 chr2:25150051 NA 0.26 4.59 0.38 1.08e-5 Body mass index; TGCT cis rs10883723 0.737 rs11191312 chr10:104278601 T/C cg05855489 chr10:104503620 C10orf26 -0.6 -5.18 -0.42 8.85e-7 Allergic disease (asthma, hay fever or eczema); TGCT cis rs778371 0.874 rs938575 chr2:233768788 G/A cg08000102 chr2:233561755 GIGYF2 -0.57 -5.64 -0.45 1.07e-7 Schizophrenia; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg16031515 chr1:205743344 RAB7L1 -0.27 -4.55 -0.38 1.28e-5 Menarche (age at onset); TGCT cis rs7615952 0.932 rs13325495 chr3:125637416 T/G cg05084668 chr3:125655381 ALG1L -0.64 -4.55 -0.38 1.24e-5 Blood pressure (smoking interaction); TGCT cis rs514406 0.679 rs11206006 chr1:53218380 A/G cg16325326 chr1:53192061 ZYG11B -0.59 -6.47 -0.5 2.09e-9 Monocyte count; TGCT cis rs4631830 0.828 rs10763567 chr10:51538169 C/A cg10326726 chr10:51549505 MSMB 0.23 4.69 0.39 7.23e-6 Prostate-specific antigen levels; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg20007245 chr22:24372913 LOC391322 -0.78 -8.46 -0.61 6.19e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7095607 0.900 rs10823155 chr10:69950196 G/A cg18986048 chr10:69913749 MYPN 0.46 5.08 0.41 1.37e-6 Lung function (FVC); TGCT cis rs7095607 0.785 rs10762190 chr10:69919905 C/A cg18986048 chr10:69913749 MYPN 0.41 4.48 0.37 1.66e-5 Lung function (FVC); TGCT cis rs9527 0.590 rs10786741 chr10:104939182 G/A cg04362960 chr10:104952993 NT5C2 0.67 5.64 0.45 1.07e-7 Arsenic metabolism; TGCT cis rs11577318 0.579 rs10794532 chr1:26694260 T/C cg14210634 chr1:25870291 LDLRAP1 0.53 4.59 0.38 1.07e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs916888 0.773 rs1378358 chr17:44787312 C/T cg17911788 chr17:44343683 NA -0.65 -6.56 -0.51 1.34e-9 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs477895 0.653 rs11231701 chr11:63893702 G/A cg04317338 chr11:64019027 PLCB3 0.75 6.19 0.49 8.06e-9 Mean platelet volume; TGCT cis rs2439831 0.681 rs3742969 chr15:43621947 A/G cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.63 0.51 9.35e-10 Lung cancer in ever smokers; TGCT cis rs4746818 1.000 rs1506770 chr10:70964357 G/A cg04149295 chr10:70884716 VPS26A 0.79 5.44 0.44 2.79e-7 Left atrial antero-posterior diameter; TGCT cis rs1878931 0.501 rs37800 chr16:3423648 T/G cg05754148 chr16:3507555 NAT15 0.33 4.61 0.38 9.98e-6 Body mass index (adult); TGCT cis rs9611565 0.921 rs5751081 chr22:41742788 A/T cg17554472 chr22:41940697 POLR3H -0.4 -4.58 -0.38 1.11e-5 Vitiligo; TGCT cis rs56399783 0.901 rs73047393 chr7:2775879 C/T cg19731401 chr7:2775893 GNA12 0.36 5.07 0.41 1.4e-6 Childhood ear infection; TGCT cis rs739496 0.579 rs1981517 chr12:112323582 A/G cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs7586879 0.828 rs13387053 chr2:25103025 G/A cg01884057 chr2:25150051 NA 0.26 4.58 0.38 1.13e-5 Body mass index; TGCT cis rs7786808 0.707 rs11770299 chr7:158228822 G/A cg01191920 chr7:158217561 PTPRN2 -0.44 -6.64 -0.51 8.76e-10 Obesity-related traits; TGCT cis rs11118844 0.793 rs10863654 chr1:221946787 G/A cg04222084 chr1:221915650 DUSP10 -0.71 -4.99 -0.41 1.96e-6 White matter lesion progression (adjusted for white matter lesion burden at baseline);White matter lesion progression; TGCT cis rs1862618 0.853 rs863840 chr5:56128999 C/G cg12311346 chr5:56204834 C5orf35 -0.7 -6.47 -0.5 2e-9 Initial pursuit acceleration; TGCT cis rs10256972 0.552 rs7805591 chr7:1210745 A/G cg18402987 chr7:1209562 NA 0.38 4.78 0.39 4.83e-6 Longevity;Endometriosis; TGCT cis rs17094222 0.504 rs11190661 chr10:102452136 C/T cg26540559 chr10:102447443 NA 0.34 4.68 0.39 7.38e-6 Body mass index;BMI (adjusted for smoking behaviour);Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs9902453 0.868 rs11080118 chr17:28475379 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.69 -6.54 -0.51 1.47e-9 Coffee consumption (cups per day); TGCT cis rs9527 0.590 rs763914 chr10:104841587 T/C cg15744005 chr10:104629667 AS3MT -0.43 -4.95 -0.41 2.35e-6 Arsenic metabolism; TGCT cis rs9916302 0.706 rs7208487 chr17:37543449 T/G cg07936489 chr17:37558343 FBXL20 0.87 6.27 0.49 5.47e-9 Glomerular filtration rate (creatinine); TGCT cis rs1403694 0.695 rs1523435 chr3:186436306 G/A cg12454167 chr3:186435060 KNG1 0.51 8.67 0.61 1.95e-14 Blood protein levels; TGCT cis rs3818285 0.544 rs7899805 chr10:111671177 G/A cg00817464 chr10:111662876 XPNPEP1 -0.32 -5.51 -0.44 2.03e-7 Superior crus of antihelix expression; TGCT cis rs2739330 0.828 rs5760102 chr22:24248761 T/C cg02953382 chr22:24373134 LOC391322 -0.78 -8.1 -0.59 4.41e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs11025559 0.773 rs16906274 chr11:20470142 T/C cg19653624 chr11:20408972 PRMT3 -0.64 -5.11 -0.42 1.2e-6 Pursuit maintenance gain; TGCT cis rs6121246 0.909 rs6060644 chr20:30265652 G/A cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7824557 0.547 rs6601570 chr8:11079367 G/A cg21775007 chr8:11205619 TDH -0.53 -4.8 -0.4 4.55e-6 Retinal vascular caliber; TGCT cis rs9611519 0.565 rs8135524 chr22:41436442 T/C cg13695892 chr22:41940480 POLR3H -0.56 -5.19 -0.42 8.23e-7 Neuroticism; TGCT cis rs73001065 0.901 rs17217098 chr19:19702384 G/A cg20644253 chr19:19431407 KIAA0892;SF4 1.07 4.76 0.39 5.22e-6 LDL cholesterol; TGCT cis rs8180040 0.701 rs1079276 chr3:47045739 C/G cg27129171 chr3:47204927 SETD2 0.74 9.77 0.66 4.58e-17 Colorectal cancer; TGCT cis rs7267979 1.000 rs6083813 chr20:25337671 A/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8030485 0.536 rs12595749 chr15:79432359 A/G cg17916960 chr15:79447300 NA 0.4 6.1 0.48 1.24e-8 Left ventricle wall thickness; TGCT cis rs6582630 0.555 rs7969922 chr12:38529491 C/T cg26384229 chr12:38710491 ALG10B 0.85 7.74 0.57 3.08e-12 Drug-induced liver injury (flucloxacillin); TGCT cis rs2038227 1 rs2038227 chr16:539140 C/A cg06259664 chr16:537672 RAB11FIP3 0.27 5.52 0.44 1.93e-7 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs7264396 0.635 rs6119672 chr20:34479767 A/G cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs9314614 0.933 rs2741098 chr8:6690276 C/T cg27319216 chr8:6693540 XKR5 0.29 4.86 0.4 3.45e-6 IgA nephropathy;White blood cell count (basophil); TGCT cis rs875971 1.000 rs35149210 chr7:65929925 T/C cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs4294134 0.529 rs62479497 chr7:135247070 T/C cg08396481 chr7:135194601 CNOT4 -0.55 -4.51 -0.38 1.46e-5 Paget's disease; TGCT cis rs7726839 0.794 rs10474792 chr5:600058 G/A cg09021430 chr5:549028 NA -0.42 -6.04 -0.48 1.66e-8 Obesity-related traits; TGCT cis rs6815814 0.731 rs28532329 chr4:38771368 C/T cg02016764 chr4:38805732 TLR1 -0.27 -4.54 -0.38 1.32e-5 Breast cancer; TGCT cis rs7104764 0.957 rs1045454 chr11:204228 G/A cg18336825 chr11:236787 PSMD13;SIRT3 -1.02 -10.55 -0.69 5.9e-19 Menarche (age at onset); TGCT cis rs6693567 0.565 rs11205371 chr1:150398510 A/G cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs9362426 0.551 rs6912282 chr6:88103000 C/T cg12350822 chr6:88032061 C6orf162;GJB7 0.45 4.78 0.39 4.92e-6 Depressive episodes in bipolar disorder; TGCT cis rs16867321 0.950 rs1919152 chr2:181507765 C/T cg23363182 chr2:181467187 NA -0.4 -5.62 -0.45 1.21e-7 Obesity; TGCT cis rs6500602 0.627 rs6500610 chr16:4529613 A/G cg08645402 chr16:4508243 NA 0.2 5.01 0.41 1.86e-6 Schizophrenia; TGCT cis rs797680 0.786 rs12406245 chr1:93860625 G/A cg17826107 chr1:92977322 EVI5 -0.23 -5.51 -0.44 2.01e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs1862618 0.853 rs11739344 chr5:56111087 A/C cg24549020 chr5:56110836 MAP3K1 0.67 5.78 0.46 5.74e-8 Initial pursuit acceleration; TGCT cis rs12765878 0.675 rs3752946 chr10:105670849 A/T cg11005552 chr10:105648138 OBFC1 0.36 6.11 0.48 1.21e-8 Coronary artery disease; TGCT cis rs2836974 0.899 rs34433511 chr21:40618883 A/C cg11890956 chr21:40555474 PSMG1 1.11 12.48 0.75 1.21e-23 Cognitive function; TGCT cis rs7809950 0.953 rs2520263 chr7:107179119 T/C cg23024343 chr7:107201750 COG5 -0.35 -5.43 -0.44 2.88e-7 Coronary artery disease; TGCT cis rs6089829 0.926 rs6011552 chr20:61667894 T/C cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7523050 0.643 rs79451947 chr1:109404130 T/A cg08274380 chr1:109419600 GPSM2 1.31 6.12 0.48 1.15e-8 Fat distribution (HIV); TGCT cis rs13242816 1.000 rs35800776 chr7:116110069 C/A cg16553024 chr7:116138462 CAV2 -0.49 -5.11 -0.42 1.17e-6 P wave duration; TGCT cis rs6896969 0.510 rs6874500 chr5:40427883 G/T cg01087697 chr5:40835557 RPL37 -0.53 -4.63 -0.38 8.91e-6 Multiple sclerosis; TGCT cis rs2115630 0.645 rs6496284 chr15:85178270 A/G cg11189052 chr15:85197271 WDR73 -0.72 -6.85 -0.52 3.12e-10 P wave terminal force; TGCT cis rs12541335 0.603 rs9792127 chr8:22180334 G/A cg09517075 chr8:22133004 PIWIL2 0.25 4.99 0.41 2.02e-6 Hypertriglyceridemia; TGCT cis rs514406 0.644 rs6662414 chr1:53198893 A/G cg16325326 chr1:53192061 ZYG11B -0.85 -11.95 -0.73 2.3e-22 Monocyte count; TGCT cis rs4713118 0.824 rs9468225 chr6:27745719 T/G cg02458000 chr6:26745757 NA -0.56 -4.91 -0.4 2.79e-6 Parkinson's disease; TGCT cis rs2180341 0.804 rs6902233 chr6:127555963 A/G cg27446573 chr6:127587934 RNF146 1.06 8.23 0.59 2.16e-13 Breast cancer; TGCT cis rs1865760 0.555 rs2051541 chr6:25945211 C/T cg03264133 chr6:25882463 NA 0.47 5.05 0.41 1.57e-6 Height; TGCT cis rs9611519 0.929 rs9611474 chr22:41434858 G/A cg03806693 chr22:41940476 POLR3H -0.7 -6.22 -0.49 6.88e-9 Neuroticism; TGCT cis rs9303542 0.559 rs2229302 chr17:46620402 G/A cg25032089 chr17:46643351 HOXB3 0.56 5.27 0.43 5.97e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs9467773 0.620 rs2451744 chr6:26633463 G/T cg15659132 chr6:26577336 NA 0.86 11.04 0.7 3.71e-20 Intelligence (multi-trait analysis); TGCT cis rs2997447 0.633 rs11247848 chr1:26357667 G/A cg19633962 chr1:26362018 EXTL1 -0.72 -4.89 -0.4 3.01e-6 QRS complex (12-leadsum); TGCT cis rs2243480 1.000 rs313813 chr7:65503500 C/T cg18252515 chr7:66147081 NA -1.3 -8.08 -0.59 4.84e-13 Diabetic kidney disease; TGCT cis rs739496 0.843 rs621899 chr12:111984851 T/C cg10833066 chr12:111807467 FAM109A 0.37 4.93 0.4 2.61e-6 Platelet count; TGCT cis rs514406 0.825 rs9661082 chr1:53245472 A/T cg01802117 chr1:53393560 SCP2 0.43 5.12 0.42 1.14e-6 Monocyte count; TGCT trans rs7076096 0.505 rs71471182 chr10:87635602 A/T cg22879689 chr7:925143 C7orf20 0.48 6.77 0.52 4.48e-10 Post-traumatic stress disorder (asjusted for relatedness); TGCT trans rs1814175 0.645 rs7395438 chr11:49877379 G/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.09 -0.71 2.8e-20 Height; TGCT cis rs1218582 0.772 rs11264290 chr1:154912300 C/T cg09359103 chr1:154839909 KCNN3 -0.62 -11.25 -0.71 1.15e-20 Prostate cancer; TGCT cis rs8062405 1.000 rs4451951 chr16:28836205 T/C cg09754948 chr16:28834200 ATXN2L 0.61 4.56 0.38 1.22e-5 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs7819412 0.539 rs11250131 chr8:11251175 C/T cg21775007 chr8:11205619 TDH -0.64 -7.01 -0.53 1.39e-10 Triglycerides; TGCT cis rs1008375 0.933 rs4698637 chr4:17632843 A/T cg18681998 chr4:17616180 MED28 1.01 11.13 0.71 2.22e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6701037 0.748 rs10912901 chr1:175138602 G/A cg00321850 chr1:175162397 KIAA0040 -0.41 -5.6 -0.45 1.32e-7 Alcohol dependence; TGCT cis rs10791097 0.653 rs11222362 chr11:130731425 T/C cg14779329 chr11:130786720 SNX19 0.27 4.89 0.4 3.11e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs2180341 0.814 rs9385424 chr6:127726796 A/G cg24812749 chr6:127587940 RNF146 0.76 6.22 0.49 7.07e-9 Breast cancer; TGCT cis rs11031096 0.655 rs1822288 chr11:4212478 C/T cg08557956 chr11:4115526 RRM1 0.52 4.83 0.4 4e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs35306767 0.903 rs12250937 chr10:900209 C/T cg26597838 chr10:835615 NA 0.76 10.71 0.69 2.41e-19 Eosinophil percentage of granulocytes; TGCT cis rs8141529 0.748 rs5752826 chr22:29269808 A/G cg02153584 chr22:29168773 CCDC117 0.63 4.87 0.4 3.3e-6 Lymphocyte counts; TGCT cis rs1153858 1.000 rs11852800 chr15:45639131 A/G cg14582100 chr15:45693742 SPATA5L1 -0.5 -5.77 -0.46 6.02e-8 Homoarginine levels; TGCT cis rs7607369 0.648 rs7582193 chr2:219652532 T/C cg02176678 chr2:219576539 TTLL4 -0.45 -5.86 -0.47 3.89e-8 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs12220238 1.000 rs11000930 chr10:75982982 C/G cg19889307 chr10:75911429 ADK;AP3M1 -0.85 -5.91 -0.47 3.14e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs1799949 0.501 rs2343819 chr17:41409653 T/G cg05368731 chr17:41323189 NBR1 1.2 14.2 0.79 8.98e-28 Menopause (age at onset); TGCT cis rs453301 0.652 rs2043129 chr8:8825504 C/G cg15556689 chr8:8085844 FLJ10661 0.67 5.53 0.44 1.79e-7 Joint mobility (Beighton score); TGCT cis rs136211 0.577 rs9607339 chr22:36768932 G/T cg16924664 chr22:36878180 TXN2 0.5 4.69 0.39 7.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs10504229 1.000 rs60231757 chr8:58169937 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs763121 0.819 rs5757160 chr22:38989646 T/C cg06022373 chr22:39101656 GTPBP1 0.81 8.26 0.6 1.84e-13 Menopause (age at onset); TGCT cis rs6964587 0.626 rs4729011 chr7:91515419 G/A cg17063962 chr7:91808500 NA -0.76 -7.15 -0.54 6.42e-11 Breast cancer; TGCT cis rs4843747 0.671 rs4075599 chr16:88107423 C/G cg06915872 chr16:87998081 BANP -0.3 -4.55 -0.38 1.25e-5 Menopause (age at onset); TGCT cis rs7582180 0.663 rs4850930 chr2:100990955 T/C cg14675211 chr2:100938903 LONRF2 0.48 4.6 0.38 1.01e-5 Intelligence (multi-trait analysis); TGCT cis rs875971 0.895 rs7788984 chr7:65915616 A/G cg11764359 chr7:65958608 NA 0.61 5.53 0.44 1.84e-7 Aortic root size; TGCT cis rs17401966 0.898 rs11587495 chr1:10448999 T/C cg19773385 chr1:10388646 KIF1B -0.24 -5.5 -0.44 2.09e-7 Hepatocellular carcinoma; TGCT cis rs7772486 0.701 rs7772717 chr6:145954854 T/C cg23711669 chr6:146136114 FBXO30 0.92 10.45 0.68 1.03e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs478304 0.651 rs11600918 chr11:65511965 A/G cg27068330 chr11:65405492 SIPA1 -0.94 -9.57 -0.65 1.41e-16 Acne (severe); TGCT cis rs1475911 1.000 rs2839467 chr21:43513200 A/G cg19766460 chr21:43528205 UMODL1;C21orf128 -0.53 -7.33 -0.55 2.55e-11 IgG glycosylation; TGCT cis rs6882046 0.513 rs676096 chr5:88035887 C/T cg24804195 chr5:87968844 LOC645323 -0.59 -5.9 -0.47 3.31e-8 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs7829975 0.714 rs12544992 chr8:8661681 C/G cg15556689 chr8:8085844 FLJ10661 0.72 6.42 0.5 2.67e-9 Mood instability; TGCT cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs12681288 0.862 rs2701899 chr8:1019581 G/A cg08872321 chr8:1308229 NA -0.26 -4.72 -0.39 6.15e-6 Schizophrenia; TGCT cis rs986417 0.818 rs10151839 chr14:60980688 T/G cg27398547 chr14:60952738 C14orf39 1.43 9.1 0.63 1.87e-15 Gut microbiota (bacterial taxa); TGCT cis rs2658782 1.000 rs2608216 chr11:93149172 G/A cg18152523 chr11:93063302 CCDC67 -0.69 -5.41 -0.44 3.11e-7 Pulmonary function decline; TGCT cis rs10751667 0.643 rs10751669 chr11:942344 C/G cg06064525 chr11:970664 AP2A2 0.35 8.1 0.59 4.49e-13 Alzheimer's disease (late onset); TGCT cis rs2469997 0.925 rs2470018 chr8:120361655 C/T cg00681363 chr8:120844660 TAF2 0.69 4.48 0.37 1.64e-5 Hypertension (SNP x SNP interaction); TGCT cis rs9788682 0.947 rs7169584 chr15:78822660 A/T cg06917634 chr15:78832804 PSMA4 -0.7 -5.01 -0.41 1.83e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs9430161 0.579 rs7542164 chr1:11040223 G/A cg02454025 chr1:11042201 C1orf127 0.97 12.71 0.75 3.27e-24 Ewing sarcoma; TGCT cis rs2549003 1.000 rs2070728 chr5:131819977 C/T cg02551604 chr5:131831745 NA -0.89 -11.95 -0.73 2.33e-22 Asthma (sex interaction); TGCT cis rs9467711 0.651 rs115648484 chr6:25938767 T/A cg16898833 chr6:26189333 HIST1H4D 1.32 5.63 0.45 1.16e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.765 rs7340412 chr2:99661148 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs1008375 0.966 rs2872957 chr4:17651757 C/A cg10189774 chr4:17578691 LAP3 0.6 5.29 0.43 5.23e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs425277 0.606 rs424079 chr1:2071340 C/A cg12140144 chr1:2984275 FLJ42875;PRDM16 0.35 4.93 0.41 2.55e-6 Height; TGCT cis rs9486719 1.000 rs12190507 chr6:96898265 T/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs6684514 1.000 rs12142808 chr1:156230546 G/A cg20302342 chr1:156215951 PAQR6 0.37 4.72 0.39 6.38e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs2455799 0.634 rs6771390 chr3:15906637 C/G cg16303742 chr3:15540471 COLQ -0.24 -4.64 -0.38 8.68e-6 Mean platelet volume; TGCT cis rs5769765 0.862 rs9616774 chr22:50290599 G/A cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs1552244 0.882 rs55840655 chr3:10042690 C/T cg00149659 chr3:10157352 C3orf10 0.73 4.72 0.39 6.17e-6 Alzheimer's disease; TGCT cis rs2739330 0.828 rs2186366 chr22:24254113 A/G cg10150615 chr22:24372951 LOC391322 1.01 13.23 0.77 1.86e-25 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs67460515 0.892 rs4856756 chr3:160999414 G/A cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT cis rs2836974 0.897 rs13049280 chr21:40594656 C/G cg11644478 chr21:40555479 PSMG1 0.96 9.88 0.66 2.44e-17 Cognitive function; TGCT cis rs6987853 0.933 rs2923430 chr8:42391195 T/C cg20539142 chr8:42623718 CHRNA6 -0.19 -4.55 -0.38 1.24e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs71435601 0.699 rs515135 chr2:21286057 T/C cg25035485 chr2:21266500 APOB 0.52 4.54 0.38 1.32e-5 Cholesterol, total; TGCT cis rs4642101 0.662 rs4034942 chr3:12836792 C/T cg05775895 chr3:12838266 CAND2 0.91 10.85 0.7 1.06e-19 QRS complex (12-leadsum); TGCT cis rs873946 0.586 rs2001426 chr10:134563871 G/A cg17054783 chr10:134559939 INPP5A 0.26 5.3 0.43 5.04e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs13191362 0.507 rs2846566 chr6:163059714 G/A cg06582575 chr6:163149167 PACRG;PARK2 -0.57 -5.28 -0.43 5.63e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs11190604 0.767 rs10883489 chr10:102194532 T/C cg23241863 chr10:102295624 HIF1AN 0.64 4.8 0.4 4.42e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4819052 1.000 rs13052356 chr21:46663588 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.77 6.05 0.48 1.56e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs10504229 1.000 rs66731170 chr8:58187895 C/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs4665304 chr2:26313406 C/T cg22920501 chr2:26401640 FAM59B -0.73 -6.28 -0.49 5.18e-9 Gut microbiome composition (summer); TGCT cis rs2115630 0.936 rs6496318 chr15:85215229 C/T cg12501888 chr15:85177176 SCAND2 -0.49 -4.77 -0.39 5.18e-6 P wave terminal force; TGCT cis rs9368481 0.761 rs4713062 chr6:26948195 A/G cg18867708 chr6:26865862 GUSBL1 -0.34 -4.56 -0.38 1.23e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs11792861 0.781 rs2297581 chr9:111755008 C/T cg14432460 chr9:111696404 IKBKAP;C9orf6 0.5 4.73 0.39 6.12e-6 Menarche (age at onset); TGCT cis rs936229 0.861 rs7176022 chr15:75107880 G/T cg10253484 chr15:75165896 SCAMP2 0.66 5.34 0.43 4.28e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs13242816 1.000 rs2191499 chr7:116138599 C/T cg16553024 chr7:116138462 CAV2 -0.44 -5.34 -0.43 4.29e-7 P wave duration; TGCT cis rs10986311 0.775 rs3758207 chr9:127132020 C/T cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.85 -0.4 3.61e-6 Vitiligo; TGCT cis rs832540 0.931 rs2662040 chr5:56246610 A/G cg24531977 chr5:56204891 C5orf35 0.5 5.21 0.42 7.64e-7 Coronary artery disease; TGCT cis rs9653442 0.648 rs11123805 chr2:100643464 A/G cg22139774 chr2:100720529 AFF3 -0.41 -7.28 -0.55 3.3e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs2458413 0.522 rs2514657 chr8:105331215 T/C cg13045555 chr8:105342365 NA -0.39 -6.2 -0.49 7.83e-9 Paget's disease; TGCT cis rs1395 0.885 rs7575245 chr2:27527321 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 0.47 6.18 0.49 8.53e-9 Blood metabolite levels; TGCT cis rs1322512 1.000 rs7744697 chr6:152948986 G/A cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs6569992 0.500 rs1022506 chr6:135511587 G/A cg22676075 chr6:135203613 NA 0.75 4.64 0.38 8.82e-6 Red blood cell traits; TGCT cis rs7100689 0.784 rs4934153 chr10:82191255 T/C cg01528321 chr10:82214614 TSPAN14 0.9 9.42 0.65 3.22e-16 Post bronchodilator FEV1; TGCT cis rs514406 0.621 rs928452 chr1:53195926 G/C cg01802117 chr1:53393560 SCP2 0.42 4.92 0.4 2.69e-6 Monocyte count; TGCT cis rs6088580 0.634 rs2378133 chr20:32919505 C/G cg08999081 chr20:33150536 PIGU -0.27 -5.19 -0.42 8.22e-7 Glomerular filtration rate (creatinine); TGCT cis rs875971 1.000 rs6961155 chr7:65933295 T/C cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs7819412 0.749 rs11991118 chr8:10939273 A/C cg21775007 chr8:11205619 TDH 0.48 4.7 0.39 6.82e-6 Triglycerides; TGCT cis rs7937682 1.000 rs11608122 chr11:111535105 C/T cg09085632 chr11:111637200 PPP2R1B 1.03 9.46 0.65 2.53e-16 Primary sclerosing cholangitis; TGCT cis rs28386778 1.000 rs2955241 chr17:61968113 G/C cg06873352 chr17:61820015 STRADA 0.55 5.69 0.46 8.57e-8 Prudent dietary pattern; TGCT cis rs854765 0.547 rs2955370 chr17:17966945 C/T cg04398451 chr17:18023971 MYO15A 0.34 5.46 0.44 2.48e-7 Total body bone mineral density; TGCT cis rs56235845 0.694 rs9313758 chr5:176773091 T/G cg06060754 chr5:176797920 RGS14 0.42 6.76 0.52 4.78e-10 Hemoglobin concentration;Hematocrit; TGCT cis rs10540 1.000 rs61876334 chr11:487201 T/C cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs3008870 1.000 rs2985824 chr1:67410171 C/T cg03991309 chr1:68237761 GNG12 -0.26 -4.57 -0.38 1.17e-5 Lymphocyte percentage of white cells; TGCT cis rs17345786 1.000 rs58907984 chr3:101305170 T/G cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.86 8.79 0.62 1.01e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs4889855 0.530 rs4303599 chr17:78566700 C/T cg16591659 chr17:78472290 NA 0.28 4.46 0.37 1.84e-5 Fractional excretion of uric acid; TGCT cis rs9611565 0.644 rs2413652 chr22:42097238 C/T cg06481639 chr22:41940642 POLR3H 0.58 4.95 0.41 2.34e-6 Vitiligo; TGCT cis rs2898290 0.500 rs11998678 chr8:11830150 A/G cg21775007 chr8:11205619 TDH -0.49 -4.58 -0.38 1.13e-5 Systolic blood pressure; TGCT cis rs1997103 1.000 rs2877284 chr7:55408778 A/G cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs7020830 0.898 rs2790063 chr9:37287405 G/A cg14294708 chr9:37120828 ZCCHC7 1.16 15.22 0.81 3.78e-30 Schizophrenia; TGCT cis rs875971 1.000 rs937495 chr7:65779798 A/G cg11764359 chr7:65958608 NA -0.61 -5.52 -0.44 1.93e-7 Aortic root size; TGCT cis rs2235642 0.750 rs2859310 chr16:1656765 C/T cg11375102 chr16:1583810 IFT140;TMEM204 0.27 4.64 0.38 8.77e-6 Coronary artery disease; TGCT trans rs9388451 0.874 rs3734634 chr6:126111800 G/A cg05039488 chr6:79577232 IRAK1BP1 -0.72 -8.03 -0.58 6.54e-13 Brugada syndrome; TGCT trans rs8073060 0.544 rs225283 chr17:33934912 A/G cg19694781 chr19:47549865 TMEM160 -0.6 -13.04 -0.76 5.29e-25 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs1018836 0.544 rs10112371 chr8:91457626 C/T cg16814680 chr8:91681699 NA 0.57 5.57 0.45 1.53e-7 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs9611519 0.929 rs9611509 chr22:41565827 A/G cg13695892 chr22:41940480 POLR3H -0.5 -4.51 -0.38 1.5e-5 Neuroticism; TGCT cis rs10504229 0.689 rs17801390 chr8:58054768 T/C cg08219700 chr8:58056026 NA 0.38 4.64 0.38 8.83e-6 Developmental language disorder (linguistic errors); TGCT cis rs11025559 0.812 rs10833338 chr11:20514709 A/G cg19653624 chr11:20408972 PRMT3 -0.61 -4.74 -0.39 5.69e-6 Pursuit maintenance gain; TGCT cis rs1372520 0.684 rs1442144 chr4:90736113 T/C cg14346243 chr4:90757452 SNCA -0.66 -5.56 -0.45 1.55e-7 Neuroticism; TGCT trans rs57221529 0.709 rs72706611 chr5:561146 C/A cg25482853 chr8:67687455 SGK3 1.21 10.33 0.68 2.02e-18 Lung disease severity in cystic fibrosis; TGCT cis rs6840360 0.571 rs7674244 chr4:152488302 T/C cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs1030877 0.557 rs2576752 chr2:105978761 A/G cg02079111 chr2:105885981 TGFBRAP1 0.17 5.27 0.43 5.93e-7 Obesity-related traits; TGCT cis rs1218582 0.745 rs1580943 chr1:154865125 G/A cg09359103 chr1:154839909 KCNN3 -0.67 -12.42 -0.74 1.61e-23 Prostate cancer; TGCT cis rs11874712 0.688 rs12954742 chr18:43703223 C/G cg20479805 chr18:43684716 ATP5A1;HAUS1 0.48 4.82 0.4 4.19e-6 Migraine - clinic-based; TGCT cis rs35883536 0.609 rs2647327 chr1:101041766 C/T cg14855972 chr1:101004472 GPR88 0.23 4.44 0.37 1.97e-5 Monocyte count; TGCT cis rs1497406 0.744 rs4233540 chr1:16507384 A/G cg20430773 chr1:16534157 ARHGEF19 -0.54 -5.71 -0.46 7.75e-8 Gamma gluatamyl transferase levels;Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg06238570 chr21:40685208 BRWD1 0.69 6.41 0.5 2.81e-9 Cognitive function; TGCT cis rs10504229 1.000 rs60454728 chr8:58173781 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs1862618 0.853 rs2548665 chr5:56131805 T/A cg03609598 chr5:56110824 MAP3K1 -0.58 -4.7 -0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs3733631 1.000 rs4141203 chr4:104638435 A/G cg24090629 chr4:104641072 TACR3 -0.74 -5.8 -0.46 5.14e-8 Menarche (age at onset); TGCT cis rs3008870 1.000 rs3008894 chr1:67377739 A/G cg03991309 chr1:68237761 GNG12 0.29 4.88 0.4 3.2e-6 Lymphocyte percentage of white cells; TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg11905131 chr22:24372483 LOC391322 -0.79 -8.45 -0.6 6.78e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9311474 0.569 rs7614981 chr3:52566914 G/T cg11041457 chr3:52719354 GNL3;PBRM1 0.53 4.95 0.41 2.37e-6 Electroencephalogram traits; TGCT cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg11062466 chr8:58055876 NA 0.45 4.83 0.4 3.91e-6 Developmental language disorder (linguistic errors); TGCT cis rs1008375 0.931 rs6449310 chr4:17575530 T/C cg10189774 chr4:17578691 LAP3 0.62 5.36 0.43 3.97e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7586879 0.598 rs6724772 chr2:25128730 T/C cg15423357 chr2:25149977 NA 0.5 4.89 0.4 3.06e-6 Body mass index; TGCT cis rs2404602 0.735 rs4886495 chr15:76738959 C/T cg22467129 chr15:76604101 ETFA -0.43 -4.6 -0.38 1.01e-5 Blood metabolite levels; TGCT cis rs6880778 0.505 rs10473189 chr5:40402692 G/C cg01087697 chr5:40835557 RPL37 0.54 4.93 0.4 2.6e-6 Inflammatory bowel disease; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg23131131 chr22:24373011 LOC391322 0.67 7.07 0.54 9.88e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7572733 0.534 rs1464211 chr2:198798630 G/A cg00792783 chr2:198669748 PLCL1 0.57 5.23 0.43 6.99e-7 Dermatomyositis; TGCT cis rs2180341 0.782 rs6912006 chr6:127722631 C/T cg24812749 chr6:127587940 RNF146 0.63 5.37 0.43 3.81e-7 Breast cancer; TGCT cis rs597539 0.616 rs631001 chr11:68642974 C/T cg21963583 chr11:68658836 MRPL21 0.36 6.1 0.48 1.25e-8 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9443645 0.869 rs7756858 chr6:79619968 A/G cg05283184 chr6:79620031 NA -0.21 -4.63 -0.38 9.16e-6 Intelligence (multi-trait analysis); TGCT trans rs7613875 0.620 rs7634441 chr3:50071677 G/A cg21659725 chr3:3221576 CRBN -0.7 -7.98 -0.58 8.35e-13 Body mass index; TGCT cis rs9911578 0.935 rs12948039 chr17:57045184 C/T cg12560992 chr17:57184187 TRIM37 0.73 8.7 0.62 1.69e-14 Intelligence (multi-trait analysis); TGCT cis rs6831352 0.879 rs29001215 chr4:100051722 T/C cg12011299 chr4:100065546 ADH4 -0.41 -4.92 -0.4 2.72e-6 Alcohol dependence; TGCT cis rs4705962 0.918 rs6879672 chr5:132025947 A/G cg13566430 chr5:131992455 IL13 -0.29 -4.44 -0.37 1.97e-5 Atopic dermatitis; TGCT cis rs9549367 0.713 rs3024747 chr13:113821787 C/G cg09473364 chr13:112927190 NA -0.3 -4.44 -0.37 1.95e-5 Platelet distribution width; TGCT cis rs8072100 0.782 rs28507314 chr17:45551402 C/T cg08085267 chr17:45401833 C17orf57 -0.48 -5.23 -0.43 6.87e-7 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs7647973 0.580 rs11130184 chr3:49229930 C/T cg06212747 chr3:49208901 KLHDC8B 0.65 6.23 0.49 6.72e-9 Menarche (age at onset); TGCT cis rs17197710 0.673 rs41310332 chr11:47348057 C/T cg13308137 chr11:47528955 CUGBP1 0.41 5.82 0.46 4.71e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9814567 1.000 rs9876658 chr3:134179453 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.97 9.98 0.67 1.45e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7429990 0.932 rs2361684 chr3:48152618 G/C cg11946769 chr3:48343235 NME6 -0.56 -4.63 -0.38 9.27e-6 Educational attainment (years of education); TGCT cis rs7178572 1.000 rs6495240 chr15:77766556 T/C cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs1448094 0.511 rs7967183 chr12:86216845 T/G cg02569458 chr12:86230093 RASSF9 0.36 4.53 0.38 1.36e-5 Major depressive disorder; TGCT cis rs1395 1.000 rs1395 chr2:27424636 G/A cg14242246 chr2:27434262 C2orf28;SLC5A6 -0.47 -6.33 -0.49 4.08e-9 Blood metabolite levels; TGCT cis rs7208859 0.623 rs77544470 chr17:28934550 C/A cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs35306767 0.953 rs35174953 chr10:961191 C/A cg20503657 chr10:835505 NA 0.68 9.49 0.65 2.12e-16 Eosinophil percentage of granulocytes; TGCT cis rs514406 0.698 rs522259 chr1:53365481 A/G cg24675658 chr1:53192096 ZYG11B -0.75 -9.11 -0.63 1.78e-15 Monocyte count; TGCT cis rs3540 0.883 rs6496676 chr15:90988384 A/T cg22089800 chr15:90895588 ZNF774 0.74 6.72 0.52 5.87e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs9868809 0.772 rs12107252 chr3:48691316 T/C cg00383909 chr3:49044727 WDR6 0.9 5.42 0.44 3.05e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs9486715 0.793 rs2499777 chr6:97013814 T/C cg06623918 chr6:96969491 KIAA0776 -1.1 -14.37 -0.79 3.55e-28 Headache; TGCT cis rs28785552 0.966 rs7247272 chr19:53236331 C/T cg04754360 chr19:53238445 ZNF611 0.58 4.73 0.39 5.89e-6 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs4808199 0.895 rs4808194 chr19:19435680 T/G cg03709012 chr19:19516395 GATAD2A 0.81 6.32 0.49 4.32e-9 Nonalcoholic fatty liver disease; TGCT cis rs9611565 0.649 rs5758442 chr22:42133060 T/C cg03806693 chr22:41940476 POLR3H 0.93 9.08 0.63 2.06e-15 Vitiligo; TGCT cis rs2982552 0.967 rs2982556 chr6:152056842 G/A cg22157087 chr6:152012887 ESR1 0.18 4.58 0.38 1.11e-5 Bone properties (heel); TGCT cis rs9796 0.835 rs28455998 chr15:41430969 T/A cg18705301 chr15:41695430 NDUFAF1 -0.48 -6.18 -0.49 8.55e-9 Menopause (age at onset); TGCT cis rs10791097 0.694 rs6590520 chr11:130747386 C/G cg12179176 chr11:130786555 SNX19 0.84 10.14 0.67 5.76e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs854765 0.547 rs2955377 chr17:17932818 G/A cg04398451 chr17:18023971 MYO15A -0.32 -5.15 -0.42 1.01e-6 Total body bone mineral density; TGCT cis rs10504229 1.000 rs56168206 chr8:58184485 G/A cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6724607 1.000 rs28452331 chr2:191471847 C/T cg10560079 chr2:191398806 TMEM194B -0.36 -5.07 -0.41 1.4e-6 Pulse pressure; TGCT cis rs6570726 0.526 rs9403699 chr6:145730685 G/T cg23711669 chr6:146136114 FBXO30 0.59 5.3 0.43 5.19e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs2243480 1.000 rs316307 chr7:65570171 C/T cg18252515 chr7:66147081 NA -1.21 -7.77 -0.57 2.59e-12 Diabetic kidney disease; TGCT cis rs9291683 0.620 rs7699512 chr4:10125808 C/T cg00071950 chr4:10020882 SLC2A9 -0.43 -4.7 -0.39 6.69e-6 Bone mineral density; TGCT cis rs36051895 0.664 rs2274649 chr9:5090934 A/T cg02405213 chr9:5042618 JAK2 -0.72 -9.52 -0.65 1.85e-16 Pediatric autoimmune diseases; TGCT cis rs7681440 0.835 rs6839608 chr4:90805493 T/C cg26578617 chr4:90757533 SNCA -0.45 -4.63 -0.38 9.12e-6 Dementia with Lewy bodies; TGCT cis rs10479542 0.784 rs7703730 chr5:178986632 C/A cg19723775 chr5:179050963 HNRNPH1 -0.5 -5.03 -0.41 1.67e-6 Lung cancer; TGCT cis rs7829975 0.711 rs4481596 chr8:8704330 G/C cg15556689 chr8:8085844 FLJ10661 0.75 7.1 0.54 8.38e-11 Mood instability; TGCT cis rs56104184 0.578 rs7254608 chr19:49395774 G/T cg15549821 chr19:49342101 PLEKHA4 -0.41 -5.3 -0.43 5.08e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg19318889 chr4:1322082 MAEA -0.25 -6.46 -0.5 2.19e-9 Longevity; TGCT cis rs736408 0.507 rs6445531 chr3:52717282 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs7208859 0.623 rs11656844 chr17:29060597 G/T cg13385521 chr17:29058706 SUZ12P 0.79 4.77 0.39 5.16e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1048238 0.506 rs6668183 chr1:16173814 G/C cg21385522 chr1:16154831 NA 0.61 6.99 0.53 1.53e-10 Systolic blood pressure; TGCT cis rs854765 0.616 rs8076747 chr17:17853595 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.73 7.36 0.55 2.19e-11 Total body bone mineral density; TGCT cis rs4820539 1.000 rs885964 chr22:23461003 G/C cg14186256 chr22:23484241 RTDR1 0.98 12.14 0.74 7.67e-23 Bone mineral density; TGCT cis rs8177253 0.555 rs4481157 chr3:133464684 G/A cg08048268 chr3:133502702 NA -0.37 -4.52 -0.38 1.43e-5 Iron status biomarkers; TGCT cis rs782590 0.582 rs2627767 chr2:55926815 A/T cg03859395 chr2:55845619 SMEK2 0.73 7.48 0.56 1.19e-11 Metabolic syndrome; TGCT cis rs2677744 0.563 rs8024249 chr15:91494249 T/C cg23684204 chr15:91497937 RCCD1 0.31 4.66 0.39 7.94e-6 Attention deficit hyperactivity disorder; TGCT cis rs3087591 0.683 rs2854306 chr17:29648146 G/A cg24425628 chr17:29625626 OMG;NF1 0.4 5.63 0.45 1.14e-7 Hip circumference; TGCT trans rs12655019 0.920 rs2271202 chr5:56208541 T/C cg25190722 chr1:3801660 DFFB 0.62 7.17 0.54 5.87e-11 Breast cancer (early onset); TGCT cis rs2456568 0.867 rs4753111 chr11:93658410 A/G cg26875233 chr11:93583750 C11orf90 -0.47 -5.83 -0.46 4.5e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs9303401 0.614 rs28651036 chr17:57080471 G/A cg02118635 chr17:56770003 RAD51C;TEX14 0.59 5.97 0.47 2.27e-8 Cognitive test performance; TGCT cis rs6121246 0.529 rs56153385 chr20:30187609 C/T cg10886678 chr20:30946050 ASXL1 -0.71 -4.8 -0.4 4.42e-6 Mean corpuscular hemoglobin; TGCT cis rs2463822 1.000 rs2513074 chr11:62100880 A/C cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs1525293 0.714 rs12698981 chr7:70508699 A/G cg21135135 chr7:70597687 WBSCR17 0.48 4.59 0.38 1.05e-5 Colonoscopy-negative controls vs population controls;Major depressive disorder; TGCT cis rs7666738 0.830 rs28444709 chr4:99028496 A/T cg18180107 chr4:99064573 C4orf37 0.57 5.31 0.43 4.94e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7824557 0.767 rs11250127 chr8:11170209 G/A cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs2153535 0.580 rs2143354 chr6:8517907 G/A cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT trans rs7613875 0.620 rs7634441 chr3:50071677 G/A cg21665057 chr3:196295764 WDR53;FBXO45 -0.83 -8.69 -0.62 1.76e-14 Body mass index; TGCT cis rs13191362 1.000 rs67042566 chr6:163006541 A/T cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs600626 0.636 rs11236517 chr11:75452721 T/C cg15975211 chr11:75525881 UVRAG 0.82 4.53 0.38 1.37e-5 Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid); TGCT cis rs10089 1.000 rs4835945 chr5:127526481 C/A cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.78 7.35 0.55 2.37e-11 Ileal carcinoids; TGCT cis rs10504229 0.679 rs16921683 chr8:58053270 T/C cg08280861 chr8:58055591 NA 0.35 4.88 0.4 3.2e-6 Developmental language disorder (linguistic errors); TGCT cis rs10465746 0.905 rs1324484 chr1:84382844 T/C cg10977910 chr1:84465055 TTLL7 0.67 6.63 0.51 9.19e-10 Obesity-related traits; TGCT trans rs66573146 0.803 rs59742225 chr4:6969942 C/T cg07817883 chr1:32538562 TMEM39B 1.56 8.31 0.6 1.45e-13 Granulocyte percentage of myeloid white cells; TGCT trans rs7618501 0.699 rs11713193 chr3:49924424 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.87 9.22 0.64 9.94e-16 Intelligence (multi-trait analysis); TGCT cis rs10883723 0.810 rs2296586 chr10:104245575 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 9.22 0.64 9.86e-16 Allergic disease (asthma, hay fever or eczema); TGCT trans rs2688608 0.592 rs13013 chr10:75562161 C/A cg13918328 chr10:52500089 ASAH2B 0.69 6.89 0.53 2.56e-10 Inflammatory bowel disease; TGCT trans rs6089829 0.925 rs11086152 chr20:61664656 T/C cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs231513 0.911 rs231517 chr17:41961789 C/T cg26893861 chr17:41843967 DUSP3 -0.73 -5.64 -0.45 1.08e-7 Cognitive function; TGCT cis rs514406 0.825 rs7523761 chr1:53250915 T/C cg22166914 chr1:53195759 ZYG11B -0.39 -6.57 -0.51 1.23e-9 Monocyte count; TGCT cis rs9858542 0.903 rs9875617 chr3:49634696 G/A cg03060546 chr3:49711283 APEH -0.63 -5.48 -0.44 2.28e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs1887596 0.624 rs9553854 chr13:27131270 T/C cg01312412 chr13:27282625 NA 0.28 5.04 0.41 1.59e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs9611565 0.512 rs45500192 chr22:42177899 A/G cg13695892 chr22:41940480 POLR3H -0.84 -7.96 -0.58 9.47e-13 Vitiligo; TGCT cis rs1865760 0.663 rs9467656 chr6:25993559 G/A cg16482183 chr6:26056742 HIST1H1C 0.56 5.05 0.41 1.52e-6 Height; TGCT cis rs782590 0.935 rs782649 chr2:55860308 T/C cg18811423 chr2:55921094 PNPT1 0.67 7.06 0.54 1.06e-10 Metabolic syndrome; TGCT cis rs7811142 0.943 rs28578163 chr7:100044754 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.07 8.99 0.63 3.48e-15 Platelet count; TGCT cis rs12510870 0.599 rs12506668 chr4:74449824 T/C cg05868023 chr4:75230803 EREG -0.54 -4.76 -0.39 5.33e-6 Iris color (b* coordinate); TGCT cis rs208520 0.690 rs12213561 chr6:66705646 T/C cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT trans rs9329221 0.711 rs55864141 chr8:9807022 T/C cg06636001 chr8:8085503 FLJ10661 -0.77 -6.81 -0.52 3.74e-10 Neuroticism; TGCT cis rs8064299 0.560 rs11077763 chr17:72786029 T/C cg25054828 chr17:72772726 NAT9;TMEM104 0.89 10.13 0.67 6.14e-18 Monocyte count; TGCT cis rs17331151 0.573 rs76029595 chr3:52868523 C/T cg12962167 chr3:53033115 SFMBT1 0.44 4.96 0.41 2.28e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs1541995 0.754 rs4984452 chr15:96233382 A/G cg00882281 chr15:96346592 NA -0.3 -4.84 -0.4 3.78e-6 Photic sneeze reflex; TGCT cis rs174601 0.861 rs174580 chr11:61606642 A/G cg19610905 chr11:61596333 FADS2 -0.96 -9.43 -0.65 3.08e-16 Blood metabolite levels;Red blood cell fatty acid levels;Liver enzyme levels (alkaline phosphatase);Gondoic acid (20:1n-9) levels;Trans fatty acid levels; TGCT cis rs6121246 0.697 rs6087716 chr20:30229040 C/T cg18721089 chr20:30220636 NA -0.53 -5.43 -0.44 2.86e-7 Mean corpuscular hemoglobin; TGCT cis rs42648 0.819 rs10953006 chr7:90030153 A/G cg25739043 chr7:89950458 NA -0.53 -4.98 -0.41 2.1e-6 Homocysteine levels; TGCT cis rs10791097 0.668 rs10791102 chr11:130744977 G/A cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs589448 0.902 rs315113 chr12:69786543 G/T cg20891283 chr12:69753455 YEATS4 -0.9 -10.42 -0.68 1.18e-18 Cerebrospinal fluid biomarker levels; TGCT trans rs1814175 0.546 rs1614397 chr11:49913384 G/C cg11707556 chr5:10655725 ANKRD33B -0.36 -7.05 -0.53 1.13e-10 Height; TGCT trans rs459571 0.834 rs379417 chr9:136890704 G/A cg09836344 chr4:1243392 C4orf42;CTBP1 -0.72 -7.83 -0.58 1.87e-12 Platelet distribution width; TGCT cis rs9326248 0.954 rs521171 chr11:117064693 C/G cg26566898 chr11:117069891 TAGLN 0.35 5.07 0.41 1.42e-6 Blood protein levels; TGCT cis rs9549367 0.789 rs2025247 chr13:113882564 C/G cg00898013 chr13:113819073 PROZ -0.4 -4.88 -0.4 3.18e-6 Platelet distribution width; TGCT trans rs2832077 0.527 rs2705690 chr21:30239245 T/A cg14791747 chr16:20752902 THUMPD1 -1.01 -10.54 -0.69 6.23e-19 Cognitive test performance; TGCT cis rs7973719 0.899 rs12424618 chr12:7344802 A/G cg07052231 chr12:7363540 PEX5 0.37 5.58 0.45 1.43e-7 IgG glycosylation; TGCT cis rs4654899 0.828 rs6668591 chr1:21066557 A/G cg01072550 chr1:21505969 NA -0.49 -7.7 -0.57 3.76e-12 Superior frontal gyrus grey matter volume; TGCT cis rs7224685 0.569 rs35578550 chr17:3996470 A/G cg09580393 chr17:4869866 SPAG7 -0.39 -4.49 -0.37 1.62e-5 Type 2 diabetes; TGCT cis rs9419702 0.538 rs9419625 chr10:133534954 T/G cg23460707 chr10:133558971 NA 0.43 4.84 0.4 3.75e-6 Survival in rectal cancer; TGCT cis rs17767294 0.614 rs72847329 chr6:27767046 T/C cg08851530 chr6:28072375 NA 1.54 7.3 0.55 3.1e-11 Parkinson's disease; TGCT cis rs2594989 0.943 rs2454499 chr3:11500531 T/C cg00170343 chr3:11313890 ATG7 0.69 5.12 0.42 1.16e-6 Circulating chemerin levels; TGCT cis rs4319547 0.656 rs2173582 chr12:122824694 A/G cg05707623 chr12:122985044 ZCCHC8 -0.6 -4.69 -0.39 7.14e-6 Body mass index; TGCT cis rs4727443 0.866 rs6963345 chr7:99618606 G/A cg13334819 chr7:99746414 C7orf59 0.56 4.71 0.39 6.63e-6 Interstitial lung disease; TGCT cis rs6430585 0.583 rs2304371 chr2:136561557 A/G cg07169764 chr2:136633963 MCM6 0.95 8.66 0.61 2.15e-14 Corneal structure; TGCT cis rs4499344 0.633 rs259262 chr19:33153951 G/A cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 9.09 0.63 2.01e-15 Mean platelet volume; TGCT cis rs10114408 0.959 rs12342427 chr9:96641701 A/C cg13679303 chr9:96623674 NA -0.36 -4.69 -0.39 6.98e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs1218582 0.772 rs1109815 chr1:154909268 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.7 -7.23 -0.54 4.37e-11 Prostate cancer; TGCT cis rs7635838 0.596 rs347598 chr3:11258289 G/C cg00170343 chr3:11313890 ATG7 0.58 5.54 0.45 1.72e-7 HDL cholesterol; TGCT cis rs12762955 0.519 rs10795306 chr10:1019138 A/T cg20503657 chr10:835505 NA -0.4 -5.29 -0.43 5.26e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs9788682 0.895 rs3813570 chr15:78832832 T/C cg24631222 chr15:78858424 CHRNA5 0.92 7.57 0.56 7.51e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs12477438 0.520 rs13023744 chr2:99738224 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.15 18.22 0.85 7.28e-37 Chronic sinus infection; TGCT cis rs12220238 0.722 rs10740440 chr10:76380366 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.59 4.54 0.38 1.29e-5 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs734999 0.545 rs4074789 chr1:2537464 A/G cg18854424 chr1:2615690 NA 0.46 5.36 0.43 4e-7 Ulcerative colitis; TGCT cis rs12368653 0.651 rs2277326 chr12:58202419 A/C cg12615879 chr12:58013172 SLC26A10 -0.51 -6.49 -0.5 1.87e-9 Multiple sclerosis; TGCT cis rs3780378 0.967 rs7037207 chr9:5043156 C/T cg02405213 chr9:5042618 JAK2 -0.58 -7.5 -0.56 1.09e-11 Eosinophil percentage of white cells;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs2243480 1.000 rs12698509 chr7:65418876 C/T cg18252515 chr7:66147081 NA -1.17 -7.49 -0.56 1.13e-11 Diabetic kidney disease; TGCT cis rs4332037 0.539 rs62444881 chr7:2052318 C/T cg25834613 chr7:1915315 MAD1L1 -0.52 -5.0 -0.41 1.87e-6 Bipolar disorder; TGCT cis rs2762353 0.595 rs1892256 chr6:25754271 C/T cg15691649 chr6:25882328 NA 0.43 5.34 0.43 4.27e-7 Blood metabolite levels; TGCT cis rs669446 0.591 rs586339 chr1:44137257 C/A cg12908607 chr1:44402522 ARTN -0.61 -6.64 -0.51 8.84e-10 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs11025559 0.812 rs10766679 chr11:20509190 T/C cg19653624 chr11:20408972 PRMT3 -0.59 -4.7 -0.39 6.9e-6 Pursuit maintenance gain; TGCT cis rs17376456 1.000 rs67150649 chr5:93292377 A/G cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs4851266 1.000 rs11684761 chr2:100826871 C/A cg07810366 chr2:100720526 AFF3 -0.38 -5.44 -0.44 2.7e-7 Educational attainment; TGCT cis rs4820539 0.966 rs2157709 chr22:23457420 T/C cg14186256 chr22:23484241 RTDR1 0.99 12.18 0.74 6.28e-23 Bone mineral density; TGCT cis rs2075371 1.000 rs2544210 chr7:133971535 C/T cg11752832 chr7:134001865 SLC35B4 0.7 6.51 0.5 1.66e-9 Mean platelet volume; TGCT cis rs4727027 0.899 rs6944096 chr7:148870026 A/G cg12479418 chr7:148823350 ZNF425;ZNF398 0.52 4.61 0.38 9.67e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs72945132 0.882 rs17160777 chr11:70163723 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs9928842 0.765 rs4479268 chr16:75224733 G/T cg09066997 chr16:75300724 BCAR1 -0.27 -4.79 -0.39 4.75e-6 Alcoholic chronic pancreatitis; TGCT cis rs4713118 0.868 rs10484401 chr6:27746590 A/T cg20933634 chr6:27740509 NA -0.36 -4.93 -0.4 2.62e-6 Parkinson's disease; TGCT cis rs12765878 0.513 rs56093138 chr10:105617908 A/C cg11005552 chr10:105648138 OBFC1 -0.36 -5.16 -0.42 9.33e-7 Coronary artery disease; TGCT cis rs4372836 1.000 rs2169748 chr2:28957753 G/A cg09522027 chr2:28974177 PPP1CB 0.54 4.61 0.38 9.87e-6 Body mass index; TGCT cis rs894734 0.567 rs7138907 chr12:54324576 C/T cg17708016 chr12:54321992 NA 0.68 5.64 0.45 1.11e-7 Adverse response to chemotherapy (neutropenia/leucopenia) (all antimetabolite drugs); TGCT cis rs2115630 1.000 rs8037423 chr15:85355494 C/T cg11189052 chr15:85197271 WDR73 -0.64 -6.15 -0.48 9.77e-9 P wave terminal force; TGCT cis rs854765 0.654 rs11078400 chr17:17757728 A/G cg04398451 chr17:18023971 MYO15A 0.29 4.57 0.38 1.15e-5 Total body bone mineral density; TGCT cis rs4746818 0.793 rs2008541 chr10:70860599 A/G cg11621586 chr10:70884670 VPS26A 1.16 8.0 0.58 7.7e-13 Left atrial antero-posterior diameter; TGCT trans rs629535 0.814 rs62513376 chr8:70086881 C/T cg21567404 chr3:27674614 NA -0.56 -8.82 -0.62 8.75e-15 Dupuytren's disease; TGCT cis rs60154123 0.505 rs115881613 chr1:210040369 C/T cg04352962 chr1:209979756 IRF6 0.69 4.73 0.39 6.04e-6 Coronary artery disease; TGCT cis rs377070 0.903 rs309403 chr4:123616822 T/C cg10495464 chr4:123653540 BBS12;LOC729338 0.46 5.08 0.42 1.35e-6 Mosquito bite size; TGCT cis rs1185460 0.967 rs1784460 chr11:118938371 A/T cg01677386 chr11:118938358 VPS11 0.5 4.53 0.38 1.39e-5 Coronary artery disease; TGCT cis rs3784262 0.669 rs4646602 chr15:58294757 G/A cg12031962 chr15:58353849 ALDH1A2 -0.44 -6.31 -0.49 4.53e-9 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9902453 1.000 rs4795525 chr17:28388487 T/A cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.56 -0.51 1.3e-9 Coffee consumption (cups per day); TGCT cis rs7582180 0.629 rs6731549 chr2:100939937 T/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.545 rs2836959 chr21:40623668 T/G cg11890956 chr21:40555474 PSMG1 -0.69 -6.63 -0.51 9.35e-10 Menarche (age at onset); TGCT cis rs67311347 0.577 rs11129870 chr3:40260406 G/A cg13683864 chr3:40499215 RPL14 -0.79 -7.4 -0.55 1.83e-11 Renal cell carcinoma; TGCT cis rs947211 0.846 rs823155 chr1:205762946 T/C cg11965913 chr1:205819406 PM20D1 0.44 4.89 0.4 3.09e-6 Parkinson's disease; TGCT cis rs10504229 0.683 rs57866073 chr8:58139138 A/G cg08280861 chr8:58055591 NA 0.46 5.33 0.43 4.45e-7 Developmental language disorder (linguistic errors); TGCT cis rs6087771 0.890 rs6089056 chr20:30325773 A/G cg13852791 chr20:30311386 BCL2L1 0.82 8.0 0.58 7.65e-13 Subcortical brain region volumes;Putamen volume; TGCT cis rs344364 0.511 rs1742464 chr16:1947335 A/G cg26617929 chr16:1858877 NA 0.27 4.9 0.4 2.99e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs6840360 0.554 rs6849111 chr4:152708874 T/C cg22705602 chr4:152727874 NA -0.33 -5.9 -0.47 3.26e-8 Intelligence (multi-trait analysis); TGCT cis rs4242434 0.672 rs4615566 chr8:22520682 T/C cg03733263 chr8:22462867 KIAA1967 -1.0 -13.83 -0.78 6.78e-27 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs244731 0.959 rs918459 chr5:176669030 C/T cg17509989 chr5:176798049 RGS14 -0.62 -7.75 -0.57 2.92e-12 Urate levels in lean individuals; TGCT cis rs611744 0.967 rs650437 chr8:109210927 T/G cg21045802 chr8:109455806 TTC35 0.52 4.72 0.39 6.21e-6 Dupuytren's disease; TGCT cis rs896854 0.517 rs10112447 chr8:95955701 C/T cg13393036 chr8:95962371 TP53INP1 -0.49 -5.66 -0.45 9.73e-8 Type 2 diabetes; TGCT cis rs2836974 0.965 rs8130984 chr21:40639966 A/C cg11644478 chr21:40555479 PSMG1 1.01 10.7 0.69 2.56e-19 Cognitive function; TGCT cis rs8016982 0.651 rs1885601 chr14:81641210 C/T cg01989461 chr14:81687754 GTF2A1 0.81 8.17 0.59 3.09e-13 Schizophrenia; TGCT cis rs7918232 0.556 rs788209 chr10:27434716 G/T cg14442939 chr10:27389572 ANKRD26 0.78 5.71 0.46 7.72e-8 Breast cancer; TGCT cis rs140365914 1 rs140365914 chr7:155106570 C/T cg06963709 chr7:155150793 NA 0.35 6.84 0.52 3.2e-10 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9368481 0.729 rs9379950 chr6:26961548 T/C cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.4 -4.76 -0.39 5.24e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs4808199 0.739 rs2240117 chr19:19418916 C/T cg03709012 chr19:19516395 GATAD2A 0.79 5.54 0.45 1.75e-7 Nonalcoholic fatty liver disease; TGCT cis rs897984 0.644 rs73524556 chr16:30823162 G/A cg02466173 chr16:30829666 NA -0.31 -5.12 -0.42 1.16e-6 Dementia with Lewy bodies; TGCT cis rs9467773 0.967 rs9295694 chr6:26512994 A/T cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs589448 0.967 rs2617834 chr12:69753365 T/C cg20891283 chr12:69753455 YEATS4 0.91 10.33 0.68 1.96e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs3540 0.513 rs2601154 chr15:90894284 T/C cg22089800 chr15:90895588 ZNF774 0.82 9.07 0.63 2.24e-15 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2797160 1.000 rs6934435 chr6:126017481 T/G cg05901451 chr6:126070800 HEY2 0.73 6.29 0.49 5.01e-9 Endometrial cancer; TGCT cis rs1538970 0.924 rs4660855 chr1:45899795 A/G cg05343316 chr1:45956843 TESK2 0.76 6.19 0.49 7.93e-9 Platelet count; TGCT cis rs7940866 0.874 rs10894306 chr11:130873882 A/C cg05962950 chr11:130786565 SNX19 0.7 6.94 0.53 1.89e-10 Schizophrenia; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg06896619 chr17:61851486 DDX42;CCDC47 -0.48 -4.65 -0.39 8.43e-6 Prudent dietary pattern; TGCT cis rs7552404 0.696 rs1417405 chr1:76457797 T/C cg10523679 chr1:76189770 ACADM 0.82 6.62 0.51 9.96e-10 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6089584 0.888 rs6061405 chr20:60617033 A/G cg16423285 chr20:60520624 NA -0.61 -6.57 -0.51 1.23e-9 Body mass index; TGCT cis rs7677751 0.708 rs2052699 chr4:55063994 C/T cg17187183 chr4:55093834 PDGFRA 0.49 6.47 0.5 2.03e-9 Corneal astigmatism; TGCT cis rs8017423 0.967 rs3825662 chr14:90723152 A/G cg04374321 chr14:90722782 PSMC1 0.76 7.71 0.57 3.59e-12 Mortality in heart failure; TGCT cis rs1971256 0.500 rs9479050 chr6:151806338 C/T cg14416726 chr6:151773293 C6orf211;RMND1 -0.74 -4.49 -0.37 1.63e-5 Endometriosis; TGCT cis rs1008375 1.000 rs2058337 chr4:17678649 C/T cg16339924 chr4:17578868 LAP3 0.58 4.94 0.41 2.44e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11578119 0.933 rs1999523 chr1:170467176 A/C cg09767346 chr1:170501363 GORAB 0.66 5.29 0.43 5.27e-7 Male-pattern baldness; TGCT cis rs10504229 0.861 rs116923397 chr8:58185162 T/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs250677 0.524 rs183140 chr5:148438803 G/T cg18129178 chr5:148520854 ABLIM3 -0.35 -5.07 -0.41 1.4e-6 Breast cancer; TGCT cis rs6933660 0.512 rs13202634 chr6:151800630 C/T cg03627880 chr6:151815985 C6orf97 -0.71 -6.64 -0.51 8.83e-10 Menarche (age at onset); TGCT cis rs6762 0.719 rs28620453 chr11:836971 G/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.45 -4.55 -0.38 1.27e-5 Mean platelet volume; TGCT cis rs360798 0.532 rs13013218 chr2:63011671 C/T cg17519650 chr2:63277830 OTX1 -0.6 -5.23 -0.43 7.02e-7 Coronary artery disease; TGCT cis rs13191362 1.000 rs34931503 chr6:163003876 T/C cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs16854884 0.673 rs34379944 chr3:143785766 G/A cg06585982 chr3:143692056 C3orf58 0.63 5.17 0.42 9.3e-7 Economic and political preferences (feminism/equality); TGCT cis rs9534288 0.762 rs1571052 chr13:46554849 A/G cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs709400 0.930 rs57447494 chr14:104034569 G/A cg26031613 chr14:104095156 KLC1 1.16 14.92 0.8 1.82e-29 Body mass index; TGCT cis rs6570726 0.905 rs442435 chr6:145815559 C/T cg23711669 chr6:146136114 FBXO30 0.7 6.6 0.51 1.09e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs9818758 0.607 rs56004653 chr3:49072228 T/C cg00383909 chr3:49044727 WDR6 1.53 5.87 0.47 3.76e-8 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs66573146 1.000 rs67405518 chr4:6965930 C/T cg00086871 chr4:6988644 TBC1D14 0.98 4.57 0.38 1.16e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs11971779 0.680 rs11980313 chr7:139034643 C/G cg07862535 chr7:139043722 LUC7L2 0.56 4.46 0.37 1.82e-5 Diisocyanate-induced asthma; TGCT cis rs7819412 0.545 rs11781155 chr8:10917560 C/T cg21775007 chr8:11205619 TDH -0.47 -4.66 -0.39 8.07e-6 Triglycerides; TGCT cis rs35146811 0.538 rs3823642 chr7:99796072 T/C cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs9457247 0.756 rs2345572 chr6:167403441 A/T cg23791538 chr6:167370224 RNASET2 -0.49 -4.63 -0.38 9.27e-6 Crohn's disease; TGCT cis rs9660992 0.547 rs12143121 chr1:205199142 A/G cg00857998 chr1:205179979 DSTYK 0.51 4.68 0.39 7.34e-6 Mean corpuscular volume;Mean platelet volume; TGCT cis rs514406 0.505 rs269289 chr1:53167151 A/C cg01802117 chr1:53393560 SCP2 -0.44 -5.12 -0.42 1.11e-6 Monocyte count; TGCT cis rs7714584 1.000 rs4579248 chr5:150268151 C/T cg22134413 chr5:150180641 NA 1.14 8.32 0.6 1.32e-13 Crohn's disease; TGCT cis rs1008375 0.932 rs3846356 chr4:17614176 C/T cg18681998 chr4:17616180 MED28 1.07 11.25 0.71 1.13e-20 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1865760 0.865 rs9467645 chr6:25955176 G/C cg16482183 chr6:26056742 HIST1H1C 0.52 4.84 0.4 3.78e-6 Height; TGCT cis rs9388451 0.805 rs1028481 chr6:126106573 G/T cg05901451 chr6:126070800 HEY2 -1.0 -14.45 -0.79 2.37e-28 Brugada syndrome; TGCT cis rs7666738 0.830 rs9998682 chr4:98939009 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs854765 0.552 rs6502624 chr17:17847936 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 0.75 7.76 0.57 2.71e-12 Total body bone mineral density; TGCT cis rs7249142 0.549 rs539 chr19:19287802 A/G cg12558012 chr19:19281197 LOC729991-MEF2B;MEF2B 0.56 5.55 0.45 1.67e-7 IgG glycosylation; TGCT cis rs2742417 0.603 rs2742453 chr3:45765858 G/A cg04837898 chr3:45731254 SACM1L -0.65 -6.95 -0.53 1.84e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs2797160 1.000 rs984040 chr6:126021277 A/G cg05901451 chr6:126070800 HEY2 0.75 6.66 0.51 8e-10 Endometrial cancer; TGCT cis rs7727544 0.716 rs6863213 chr5:131575932 C/T cg22598563 chr5:131563921 P4HA2 -0.29 -4.75 -0.39 5.6e-6 Blood metabolite levels; TGCT cis rs12049351 0.774 rs6704265 chr1:229633056 C/A cg12130225 chr1:229698885 NA 0.39 4.59 0.38 1.06e-5 Circulating myeloperoxidase levels (plasma); TGCT cis rs7552404 0.824 rs1251079 chr1:76189445 C/T cg10523679 chr1:76189770 ACADM 1.0 14.68 0.8 6.64e-29 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10883723 0.810 rs1884929 chr10:104275418 C/T cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT trans rs7618501 0.633 rs9861216 chr3:50059339 A/G cg21665057 chr3:196295764 WDR53;FBXO45 -0.86 -9.4 -0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.555 rs10880625 chr12:38526612 A/C cg26384229 chr12:38710491 ALG10B 0.89 8.13 0.59 3.76e-13 Drug-induced liver injury (flucloxacillin); TGCT cis rs137603 0.933 rs137593 chr22:39690021 C/T cg17798944 chr22:39715225 SNORD43;RPL3 -0.54 -5.07 -0.41 1.42e-6 Primary biliary cholangitis; TGCT cis rs1008375 0.931 rs10019482 chr4:17578079 G/A cg18681998 chr4:17616180 MED28 0.94 9.56 0.65 1.44e-16 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.511 rs75967910 chr8:58024231 C/G cg21724239 chr8:58056113 NA 0.48 5.12 0.42 1.11e-6 Developmental language disorder (linguistic errors); TGCT cis rs28595532 0.841 rs10019311 chr4:119785458 G/A cg14228332 chr4:119757509 SEC24D 1.19 6.66 0.51 8.07e-10 Cannabis dependence symptom count; TGCT cis rs113084984 0.718 rs4669746 chr2:11682018 G/A cg25804072 chr2:10829725 NOL10 0.55 4.7 0.39 6.88e-6 Breast cancer; TGCT cis rs1799949 1.000 rs8074136 chr17:41342313 A/C cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs7681440 0.874 rs1372523 chr4:90775923 G/A cg20003494 chr4:90757398 SNCA -0.56 -5.35 -0.43 4.11e-7 Dementia with Lewy bodies; TGCT cis rs6840360 0.615 rs1877188 chr4:152607931 T/C cg22705602 chr4:152727874 NA -0.32 -5.44 -0.44 2.76e-7 Intelligence (multi-trait analysis); TGCT cis rs2806561 0.734 rs2806564 chr1:23506685 T/C cg12483005 chr1:23474871 LUZP1 0.37 4.76 0.39 5.23e-6 Height; TGCT cis rs899997 0.862 rs8032552 chr15:78971136 T/C cg04896959 chr15:78267971 NA -0.3 -4.49 -0.37 1.64e-5 Coronary artery disease or large artery stroke; TGCT cis rs765787 0.530 rs12917187 chr15:45538297 A/G cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs2204008 0.557 rs11520191 chr12:38197057 T/A cg26384229 chr12:38710491 ALG10B 0.87 7.64 0.57 5.22e-12 Bladder cancer; TGCT cis rs1799949 0.536 rs4793227 chr17:41412250 A/C cg05368731 chr17:41323189 NBR1 1.1 12.58 0.75 6.92e-24 Menopause (age at onset); TGCT cis rs7246657 1.000 rs7246657 chr19:37747108 C/T cg24025825 chr19:37761650 NA 0.25 4.53 0.38 1.34e-5 Coronary artery calcification; TGCT cis rs10504229 1.000 rs59797486 chr8:58174435 T/C cg21724239 chr8:58056113 NA 0.35 4.76 0.39 5.26e-6 Developmental language disorder (linguistic errors); TGCT cis rs921968 1.000 rs56191141 chr2:219272145 A/G cg02176678 chr2:219576539 TTLL4 -0.41 -5.53 -0.45 1.78e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs909002 0.830 rs10914460 chr1:32113216 T/C cg11573219 chr1:32083031 HCRTR1 -0.41 -5.31 -0.43 4.9e-7 Intelligence (multi-trait analysis); TGCT cis rs4700695 0.841 rs957526 chr5:65345830 A/G cg21114390 chr5:65439923 SFRS12 0.62 4.69 0.39 7.22e-6 Facial morphology (factor 19); TGCT cis rs10504229 1.000 rs76944716 chr8:58191643 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.14 -0.42 1.03e-6 Developmental language disorder (linguistic errors); TGCT cis rs250677 1.000 rs40525 chr5:148432932 G/T cg18129178 chr5:148520854 ABLIM3 0.44 6.1 0.48 1.22e-8 Breast cancer; TGCT cis rs1044826 0.597 rs1017468 chr3:139145778 A/G cg00490450 chr3:139108681 COPB2 0.53 4.56 0.38 1.2e-5 Obesity-related traits; TGCT cis rs79349575 0.749 rs519537 chr17:46971140 G/A cg07967210 chr17:47022446 SNF8 0.44 5.9 0.47 3.17e-8 Type 2 diabetes; TGCT cis rs28386778 0.897 rs2036911 chr17:61794839 A/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.14 0.42 1.06e-6 Prudent dietary pattern; TGCT cis rs9443645 0.901 rs9352670 chr6:79584433 A/G cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs6671200 0.831 rs9659908 chr1:95656127 C/T cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs9653442 0.712 rs6749757 chr2:100730111 A/C cg22139774 chr2:100720529 AFF3 0.4 6.84 0.52 3.26e-10 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs910316 1.000 rs12879542 chr14:75507525 C/T cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.32e-6 Height; TGCT cis rs9682041 0.736 rs34237232 chr3:170063753 C/T cg07589077 chr3:170072950 NA -0.35 -4.99 -0.41 2.01e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs138249 0.699 rs138221 chr22:50555299 G/T cg24864161 chr22:50528282 MOV10L1 0.48 5.14 0.42 1.03e-6 Gestational age at birth in labor-initiated deliveries (child effect); TGCT cis rs4509693 1.000 rs6584394 chr10:102497258 G/A cg24127310 chr10:102502104 NA 0.7 5.86 0.47 3.84e-8 Alzheimer's disease; TGCT cis rs1862618 0.802 rs4389648 chr5:56103602 A/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.82 -0.52 3.63e-10 Initial pursuit acceleration; TGCT cis rs62244186 0.748 rs13319803 chr3:44635461 G/A cg15687855 chr3:44754131 ZNF502 -0.43 -5.09 -0.42 1.29e-6 Depressive symptoms; TGCT cis rs3771570 0.818 rs73008126 chr2:242443157 A/C cg21155796 chr2:242212141 HDLBP 0.9 6.4 0.5 2.94e-9 Prostate cancer; TGCT cis rs9467773 0.935 rs1056668 chr6:26510605 C/T cg02458000 chr6:26745757 NA 0.52 5.07 0.41 1.44e-6 Intelligence (multi-trait analysis); TGCT cis rs2479724 0.868 rs2249703 chr6:41814760 A/G cg08135965 chr6:41755394 TOMM6 0.48 4.64 0.38 8.66e-6 Menarche (age at onset); TGCT cis rs9611565 1.000 rs1109151 chr22:41752944 A/G cg13695892 chr22:41940480 POLR3H -0.82 -8.22 -0.59 2.36e-13 Vitiligo; TGCT cis rs9393692 0.905 rs7761298 chr6:26278436 C/T cg05868516 chr6:26286170 HIST1H4H 0.56 5.35 0.43 4.01e-7 Educational attainment; TGCT cis rs35306767 0.953 rs12259338 chr10:969377 C/T cg20503657 chr10:835505 NA 0.65 9.44 0.65 2.93e-16 Eosinophil percentage of granulocytes; TGCT cis rs6089584 0.888 rs6061982 chr20:60620673 C/T cg13665807 chr20:60559372 TAF4 -0.46 -4.9 -0.4 2.87e-6 Body mass index; TGCT cis rs854765 0.682 rs13306736 chr17:17740281 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.6 -5.62 -0.45 1.19e-7 Total body bone mineral density; TGCT cis rs926938 0.527 rs360580 chr1:115462334 A/G cg12756093 chr1:115239321 AMPD1 0.34 4.95 0.41 2.35e-6 Autism; TGCT cis rs7635838 0.819 rs7637414 chr3:11522228 C/G cg00170343 chr3:11313890 ATG7 0.69 6.67 0.51 7.44e-10 HDL cholesterol; TGCT cis rs72634258 0.554 rs4908694 chr1:7850898 C/T cg26816564 chr1:7831052 VAMP3 0.88 6.36 0.5 3.57e-9 Inflammatory bowel disease; TGCT cis rs2574985 0.548 rs2339505 chr10:52258106 C/T cg12753529 chr10:51525504 NA 0.22 4.44 0.37 1.95e-5 Subjective well-being; TGCT cis rs11673344 0.598 rs826326 chr19:37494765 T/C cg08039142 chr19:36980659 ZNF566 0.57 5.44 0.44 2.74e-7 Obesity-related traits; TGCT cis rs79349575 0.756 rs62078385 chr17:47045009 C/T cg07967210 chr17:47022446 SNF8 0.45 6.27 0.49 5.37e-9 Type 2 diabetes; TGCT cis rs9549367 0.601 rs558869 chr13:113849932 G/T cg09473364 chr13:112927190 NA 0.29 4.64 0.38 8.73e-6 Platelet distribution width; TGCT cis rs7824557 0.564 rs13274106 chr8:11233958 A/G cg21775007 chr8:11205619 TDH -0.67 -6.55 -0.51 1.35e-9 Retinal vascular caliber; TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 16.07 0.82 4.21e-32 Prudent dietary pattern; TGCT cis rs7819412 0.875 rs11250121 chr8:11060311 A/C cg21775007 chr8:11205619 TDH -0.49 -4.76 -0.39 5.36e-6 Triglycerides; TGCT cis rs796364 0.616 rs7589545 chr2:200676102 T/A cg17644776 chr2:200775616 C2orf69 0.34 4.84 0.4 3.76e-6 Schizophrenia; TGCT cis rs28386778 0.897 rs1062790 chr17:61896455 A/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs9952991 0.566 rs482160 chr18:12855646 A/G cg23544223 chr18:12777786 NA 0.54 4.71 0.39 6.43e-6 Inflammatory skin disease; TGCT cis rs6121246 1.000 rs6121246 chr20:30433352 C/T cg18721089 chr20:30220636 NA -0.45 -4.98 -0.41 2.12e-6 Mean corpuscular hemoglobin; TGCT cis rs3806843 0.576 rs246007 chr5:140338748 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs56235845 0.665 rs4976685 chr5:176766177 C/T cg06060754 chr5:176797920 RGS14 -0.41 -6.42 -0.5 2.67e-9 Hemoglobin concentration;Hematocrit; TGCT cis rs1215050 0.547 rs6837669 chr4:98630162 T/G cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.29e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.830 rs11726604 chr4:99000969 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 1.000 rs28693609 chr4:17645233 C/T cg18681998 chr4:17616180 MED28 1.0 11.88 0.73 3.32e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2762353 0.595 rs13194155 chr6:25755508 C/T cg03264133 chr6:25882463 NA 0.74 7.71 0.57 3.43e-12 Blood metabolite levels; TGCT cis rs7666738 0.830 rs7691864 chr4:98971376 G/C cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3540 0.960 rs28539372 chr15:91021412 T/A cg22089800 chr15:90895588 ZNF774 0.73 6.73 0.52 5.61e-10 Allergic disease (asthma, hay fever or eczema);Lymphocyte counts; TGCT cis rs2239785 0.959 rs713929 chr22:36657596 A/G cg15716373 chr22:36655542 APOL1 -0.43 -4.92 -0.4 2.64e-6 Glomerulosclerosis; TGCT cis rs12477438 0.520 rs11890338 chr2:99767868 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT trans rs16892673 0.643 rs7774267 chr6:161901679 T/C cg14035368 chr9:139258938 CARD9;DNLZ -0.81 -6.62 -0.51 9.69e-10 Aging; TGCT cis rs1153858 0.887 rs7164139 chr15:45670851 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.08 0.8 7.99e-30 Homoarginine levels; TGCT cis rs7829975 0.623 rs7010753 chr8:8373956 A/G cg15556689 chr8:8085844 FLJ10661 0.76 7.39 0.55 1.93e-11 Mood instability; TGCT cis rs2115630 0.645 rs4842978 chr15:85197253 T/C cg11189052 chr15:85197271 WDR73 -0.79 -7.82 -0.57 1.99e-12 P wave terminal force; TGCT cis rs10504229 1.000 rs61212428 chr8:58173963 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.584 rs11205997 chr1:53195271 G/C cg22166914 chr1:53195759 ZYG11B -0.5 -9.42 -0.65 3.19e-16 Monocyte count; TGCT cis rs9611565 1.000 rs1109151 chr22:41752944 A/G cg02107564 chr22:41488750 EP300 -0.56 -4.7 -0.39 6.9e-6 Vitiligo; TGCT cis rs597539 0.617 rs669659 chr11:68635623 G/C cg11716795 chr11:68671300 MRPL21;IGHMBP2 0.84 8.16 0.59 3.1400000000000003e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6532194 0.614 rs3775443 chr4:90715674 A/C cg07409292 chr4:90228685 GPRIN3 0.95 4.61 0.38 1.01e-5 Parkinson's disease; TGCT cis rs873946 0.564 rs35831787 chr10:134546346 T/C cg18305652 chr10:134549665 INPP5A 0.33 5.2 0.42 8.08e-7 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs4478858 0.684 rs7521463 chr1:31761936 T/A cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs7666738 0.715 rs61114099 chr4:98931270 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs2216164 1.000 rs12313214 chr12:68526290 C/T cg17065850 chr12:67807625 NA 0.24 4.56 0.38 1.23e-5 Alopecia areata; TGCT cis rs7845219 0.544 rs34208552 chr8:95908067 C/G cg16049864 chr8:95962084 TP53INP1 -0.5 -5.39 -0.44 3.35e-7 Type 2 diabetes; TGCT cis rs514406 0.793 rs4500255 chr1:53213279 A/G cg16325326 chr1:53192061 ZYG11B -0.73 -8.95 -0.63 4.41e-15 Monocyte count; TGCT cis rs13118159 0.509 rs4974556 chr4:1358141 G/C cg05025164 chr4:1340916 KIAA1530 0.78 6.86 0.52 2.86e-10 Longevity; TGCT cis rs9814567 0.964 rs6772406 chr3:134210183 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7647973 1.000 rs940045 chr3:49449638 G/A cg07690219 chr3:49449608 TCTA;RHOA -0.53 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs12188164 0.686 rs72711369 chr5:420517 C/T cg22025206 chr5:502436 SLC9A3 -0.26 -4.59 -0.38 1.06e-5 Cystic fibrosis severity; TGCT cis rs739496 0.527 rs11066089 chr12:112363267 C/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs224278 0.782 rs192007 chr10:64586395 G/A cg22903908 chr10:64578919 EGR2 0.38 4.76 0.39 5.38e-6 Ewing sarcoma; TGCT cis rs6540559 0.673 rs17015183 chr1:209948711 A/C cg22029157 chr1:209979665 IRF6 0.76 5.66 0.45 1.01e-7 Cleft lip with or without cleft palate; TGCT cis rs6674176 0.660 rs11210936 chr1:44391438 A/T cg13606994 chr1:44402422 ARTN -0.51 -5.48 -0.44 2.29e-7 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs9733 0.565 rs11804276 chr1:150685761 T/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.91 0.4 2.76e-6 Tonsillectomy; TGCT cis rs13256369 0.802 rs13280101 chr8:8562773 G/A cg18904891 chr8:8559673 CLDN23 0.58 5.4 0.44 3.23e-7 Obesity-related traits; TGCT cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg22920501 chr2:26401640 FAM59B -0.81 -6.42 -0.5 2.63e-9 Gut microbiome composition (summer); TGCT cis rs1878931 0.582 rs9635562 chr16:3416689 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.76 6.35 0.5 3.66e-9 Body mass index (adult); TGCT cis rs9916302 0.561 rs12453198 chr17:37741879 T/C cg07936489 chr17:37558343 FBXL20 -0.7 -5.49 -0.44 2.21e-7 Glomerular filtration rate (creatinine); TGCT cis rs7208859 0.673 rs73265612 chr17:29225983 A/G cg14008862 chr17:28927542 LRRC37B2 0.72 4.66 0.39 8.18e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs868036 0.609 rs13329413 chr15:68097126 C/T cg27219399 chr15:67835830 MAP2K5 0.34 4.49 0.37 1.6e-5 Restless legs syndrome; TGCT cis rs1801251 0.963 rs13424351 chr2:233573629 A/G cg08000102 chr2:233561755 GIGYF2 0.63 6.47 0.5 2.07e-9 Coronary artery disease; TGCT cis rs10504229 0.953 rs6985942 chr8:58173412 T/C cg24829409 chr8:58192753 C8orf71 -0.51 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs208520 1.000 rs72884017 chr6:66992513 T/G cg07460842 chr6:66804631 NA 0.78 6.82 0.52 3.61e-10 Exhaled nitric oxide output; TGCT cis rs6684514 0.542 rs11264472 chr1:156292366 A/G cg16558208 chr1:156270281 VHLL 0.28 5.05 0.41 1.52e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6977660 0.652 rs58559474 chr7:19751569 C/T cg05791153 chr7:19748676 TWISTNB 1.21 7.93 0.58 1.07e-12 Thyroid stimulating hormone; TGCT cis rs921968 0.643 rs508157 chr2:219435288 G/A cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7617773 0.674 rs13069029 chr3:48355024 A/G cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs4808199 0.948 rs1859287 chr19:19422187 T/C cg20644253 chr19:19431407 KIAA0892;SF4 0.69 5.48 0.44 2.24e-7 Nonalcoholic fatty liver disease; TGCT cis rs7172809 0.573 rs60761381 chr15:77533844 G/C cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT cis rs904251 0.704 rs2776873 chr6:37483142 A/G cg25019722 chr6:37503610 NA -0.47 -5.7 -0.46 8.29e-8 Cognitive performance; TGCT cis rs7681440 0.874 rs10028246 chr4:90766704 G/A cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs11574514 0.744 rs75204333 chr16:67574408 T/C cg00545966 chr16:67701244 C16orf86;C16orf48 0.72 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs889312 0.500 rs865570 chr5:56161975 C/T cg24531977 chr5:56204891 C5orf35 -0.5 -5.09 -0.42 1.28e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs6903823 0.508 rs1778484 chr6:28240798 A/G cg18815343 chr6:28367644 ZSCAN12 -0.44 -4.59 -0.38 1.09e-5 Pulmonary function; TGCT cis rs7523875 1.000 rs7523875 chr1:211391316 A/T cg01421119 chr1:211555733 C1orf97 0.44 4.52 0.38 1.43e-5 Mean corpuscular volume; TGCT cis rs13256369 0.901 rs12681327 chr8:8566414 G/T cg18904891 chr8:8559673 CLDN23 0.59 5.52 0.44 1.93e-7 Obesity-related traits; TGCT trans rs12599106 0.792 rs76039834 chr16:34598453 G/A cg18110333 chr6:292329 DUSP22 -0.67 -7.41 -0.55 1.7e-11 Menopause (age at onset); TGCT cis rs9660180 0.868 rs72634846 chr1:1704915 C/G cg23982607 chr1:1823379 GNB1 -0.55 -8.57 -0.61 3.52e-14 Body mass index; TGCT cis rs910316 1.000 rs11623413 chr14:75588824 C/T cg23033748 chr14:75592666 NEK9 -0.27 -4.71 -0.39 6.5e-6 Height; TGCT cis rs523522 0.923 rs1048830 chr12:120882217 G/T cg27279351 chr12:120934652 DYNLL1 0.74 6.4 0.5 2.95e-9 High light scatter reticulocyte count; TGCT cis rs11585357 0.895 rs2501795 chr1:17633499 A/G cg08277548 chr1:17600880 PADI3 -0.91 -9.56 -0.65 1.49e-16 Hair shape; TGCT cis rs10791097 0.694 rs11222370 chr11:130744767 T/G cg05962950 chr11:130786565 SNX19 0.92 11.55 0.72 2.13e-21 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs66573146 0.634 rs55633489 chr4:6988745 C/A cg00086871 chr4:6988644 TBC1D14 0.94 4.62 0.38 9.61e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs9325144 0.647 rs3759139 chr12:39087609 G/A cg26384229 chr12:38710491 ALG10B -0.55 -5.1 -0.42 1.22e-6 Morning vs. evening chronotype; TGCT cis rs2034088 0.833 rs11247554 chr17:407465 C/A cg06217071 chr17:408420 NA 0.34 5.14 0.42 1.04e-6 Hip circumference adjusted for BMI; TGCT cis rs2032447 0.714 rs199734 chr6:25940393 G/C cg07061783 chr6:25882402 NA -0.69 -6.8 -0.52 3.86e-10 Intelligence (multi-trait analysis); TGCT cis rs79349575 0.783 rs61576918 chr17:46985593 A/C cg07967210 chr17:47022446 SNF8 0.43 6.06 0.48 1.54e-8 Type 2 diabetes; TGCT cis rs797680 0.786 rs7532195 chr1:93617403 T/G cg17826107 chr1:92977322 EVI5 -0.23 -5.0 -0.41 1.88e-6 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs7607369 0.782 rs514799 chr2:219411203 A/G cg02176678 chr2:219576539 TTLL4 0.48 6.78 0.52 4.32e-10 Red blood cell count;Amyotrophic lateral sclerosis; TGCT cis rs13108904 0.870 rs12642797 chr4:1245990 G/A cg00684032 chr4:1343700 KIAA1530 0.21 4.53 0.38 1.39e-5 Obesity-related traits; TGCT cis rs7659604 0.502 rs13108419 chr4:122687238 A/G cg06713675 chr4:122721982 EXOSC9 0.37 4.64 0.38 8.68e-6 Type 2 diabetes; TGCT cis rs2880765 0.835 rs4360874 chr15:86040820 A/T cg13263323 chr15:86062960 AKAP13 -0.22 -4.77 -0.39 5e-6 Coronary artery disease; TGCT cis rs739496 0.579 rs3782885 chr12:112282583 G/A cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs2836950 0.545 rs2836952 chr21:40616651 G/C cg17971929 chr21:40555470 PSMG1 -0.54 -4.84 -0.4 3.86e-6 Menarche (age at onset); TGCT cis rs17601876 0.651 rs12050772 chr15:51544871 T/G cg19946085 chr15:51559439 CYP19A1 -0.34 -4.86 -0.4 3.5e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs28386778 0.734 rs7210724 chr17:61799198 T/C cg11494091 chr17:61959527 GH2 0.6 14.51 0.79 1.71e-28 Prudent dietary pattern; TGCT cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.02 8.55 0.61 3.84e-14 Platelet count; TGCT cis rs3806843 1.000 rs4151682 chr5:140201264 C/T cg19875535 chr5:140030758 IK 0.36 5.84 0.46 4.29e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs2243480 0.901 rs1701759 chr7:65470932 G/T cg18252515 chr7:66147081 NA -1.31 -8.18 -0.59 2.87e-13 Diabetic kidney disease; TGCT cis rs274567 0.501 rs274571 chr5:131712125 A/G cg24060327 chr5:131705240 SLC22A5 0.78 8.46 0.61 6.22e-14 Blood metabolite levels; TGCT cis rs28386778 0.897 rs2665844 chr17:61874455 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.53 4.71 0.39 6.53e-6 Prudent dietary pattern; TGCT cis rs7727544 0.581 rs10075801 chr5:131677642 A/G cg14196790 chr5:131705035 SLC22A5 0.34 4.81 0.4 4.37e-6 Blood metabolite levels; TGCT cis rs11997175 0.574 rs4236733 chr8:33655582 G/A ch.8.33884649F chr8:33765107 NA 0.28 4.54 0.38 1.33e-5 Body mass index; TGCT cis rs1129187 0.755 rs9471988 chr6:42944773 T/C cg09436375 chr6:42928200 GNMT -0.42 -5.54 -0.45 1.76e-7 Alzheimer's disease in APOE e4+ carriers; TGCT cis rs12142240 0.698 rs6697123 chr1:46811310 A/C cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs611744 0.647 rs11774904 chr8:109273435 G/A cg21045802 chr8:109455806 TTC35 0.7 7.13 0.54 7.42e-11 Dupuytren's disease; TGCT cis rs3785574 0.962 rs57553639 chr17:61848499 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.12 15.17 0.81 4.81e-30 Height; TGCT cis rs6582630 0.519 rs1851121 chr12:38389467 T/C cg13010199 chr12:38710504 ALG10B 0.58 4.59 0.38 1.05e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs875971 1.000 rs697970 chr7:65560052 G/C cg18876405 chr7:65276391 NA -0.35 -5.31 -0.43 4.85e-7 Aortic root size; TGCT cis rs4455778 0.536 rs38773 chr7:48939501 T/C cg26309511 chr7:48887640 NA 0.48 5.71 0.46 8.04e-8 Lung cancer in never smokers; TGCT cis rs7949030 0.596 rs11231138 chr11:62316195 C/G cg22862634 chr11:62369728 EML3;MTA2 0.71 8.79 0.62 1.04e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs4713675 0.649 rs568901 chr6:33710038 A/G cg07979401 chr6:33739406 LEMD2 0.34 4.66 0.39 8e-6 Plateletcrit; TGCT cis rs6840360 0.615 rs6535822 chr4:152679722 A/G cg22705602 chr4:152727874 NA -0.35 -5.94 -0.47 2.63e-8 Intelligence (multi-trait analysis); TGCT cis rs3796619 1.000 rs1466215 chr4:1072220 C/T cg27284194 chr4:1044797 NA 0.46 4.45 0.37 1.85e-5 Recombination rate (males); TGCT cis rs4711350 1.000 rs2395447 chr6:33743174 T/C cg00334056 chr6:33755658 LEMD2 -0.29 -4.63 -0.38 9.08e-6 Schizophrenia; TGCT cis rs7811142 0.945 rs34989573 chr7:100097895 C/T cg21679810 chr7:100027352 MEPCE;ZCWPW1 0.72 5.02 0.41 1.76e-6 Platelet count; TGCT cis rs950169 0.579 rs11633088 chr15:84672181 A/T cg11189052 chr15:85197271 WDR73 -0.66 -5.14 -0.42 1.04e-6 Schizophrenia; TGCT cis rs4285028 0.948 rs12493952 chr3:121708497 C/T cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs6714710 0.627 rs11680883 chr2:98472610 T/C cg26665480 chr2:98280029 ACTR1B 0.68 6.37 0.5 3.38e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT trans rs1499614 0.803 rs1796229 chr7:66119661 G/A cg07424592 chr7:64974309 NA 1.35 8.11 0.59 4.14e-13 Gout; TGCT cis rs7618915 0.547 rs2289250 chr3:52682946 A/C cg07507251 chr3:52567010 NT5DC2 -0.48 -6.9 -0.53 2.39e-10 Bipolar disorder; TGCT cis rs6570726 0.791 rs6912079 chr6:145894949 G/A cg05347473 chr6:146136440 FBXO30 0.54 5.12 0.42 1.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs3771570 1.000 rs62193197 chr2:242294301 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs7208859 0.623 rs11650982 chr17:29129955 A/G cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9921338 0.961 rs7195536 chr16:11442028 T/C cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.37e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs10479542 0.544 rs10056863 chr5:179005100 G/A cg09060608 chr5:178986726 RUFY1 0.53 6.01 0.48 1.9e-8 Lung cancer; TGCT cis rs75686122 1.000 rs79392847 chr8:104473649 G/C cg04852977 chr8:104510831 NA 0.6 4.47 0.37 1.74e-5 Cocaine dependence; TGCT cis rs3812831 0.695 rs8000778 chr13:114944310 T/C cg06611532 chr13:114900021 NA 0.34 6.17 0.48 8.73e-9 Schizophrenia; TGCT cis rs2224391 1.000 rs13191012 chr6:5261292 G/A cg09085698 chr6:5261316 LYRM4;FARS2 -0.8 -6.02 -0.48 1.87e-8 Height; TGCT cis rs7811142 1.000 rs11763511 chr7:100081944 G/A cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg11494091 chr17:61959527 GH2 0.61 14.49 0.79 1.92e-28 Prudent dietary pattern; TGCT cis rs9325144 0.957 rs1995419 chr12:38950726 C/G cg10518543 chr12:38710700 ALG10B 0.53 4.45 0.37 1.91e-5 Morning vs. evening chronotype; TGCT cis rs68170813 0.559 rs12535258 chr7:106971050 T/C cg02696742 chr7:106810147 HBP1 -0.68 -5.64 -0.45 1.09e-7 Coronary artery disease; TGCT cis rs3845702 0.866 rs818659 chr2:180870893 G/A cg01881094 chr2:180872142 CWC22 0.68 6.11 0.48 1.16e-8 Schizophrenia; TGCT cis rs2842992 0.692 rs9347342 chr6:160193129 T/C cg11366901 chr6:160182831 ACAT2 0.74 5.55 0.45 1.65e-7 Age-related macular degeneration (geographic atrophy); TGCT cis rs10504229 0.775 rs56155911 chr8:58163247 C/T cg24829409 chr8:58192753 C8orf71 -0.57 -4.72 -0.39 6.14e-6 Developmental language disorder (linguistic errors); TGCT cis rs7267979 1.000 rs2482927 chr20:25327151 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs727563 0.520 rs132773 chr22:42031768 T/A cg06634786 chr22:41940651 POLR3H 0.88 8.38 0.6 9.48e-14 Crohn's disease;Inflammatory bowel disease; TGCT cis rs2019216 0.500 rs2880292 chr17:21869537 A/G cg22648282 chr17:21454238 C17orf51 -0.57 -5.13 -0.42 1.08e-6 Pelvic organ prolapse; TGCT cis rs11992186 0.597 rs11781841 chr8:8595263 T/A cg17143192 chr8:8559678 CLDN23 -0.53 -5.12 -0.42 1.13e-6 Neuroticism; TGCT cis rs12142240 0.698 rs17361887 chr1:46834775 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.86 -0.4 3.44e-6 Menopause (age at onset); TGCT cis rs1153858 0.723 rs4580098 chr15:45596909 T/A cg26924012 chr15:45694286 SPATA5L1 1.01 11.05 0.7 3.45e-20 Homoarginine levels; TGCT cis rs752010 0.645 rs1109254 chr1:42091770 T/C cg06885757 chr1:42089581 HIVEP3 0.27 4.98 0.41 2.05e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs4319547 0.695 rs10773167 chr12:122934001 C/T cg05707623 chr12:122985044 ZCCHC8 -0.73 -5.73 -0.46 7.18e-8 Body mass index; TGCT cis rs478304 0.651 rs948494 chr11:65552118 G/A cg17480646 chr11:65405466 SIPA1 -0.55 -6.45 -0.5 2.25e-9 Acne (severe); TGCT cis rs2075371 0.501 rs1613152 chr7:134019837 A/G cg11752832 chr7:134001865 SLC35B4 0.58 4.86 0.4 3.43e-6 Mean platelet volume; TGCT cis rs9926296 0.585 rs4785595 chr16:89835521 C/T cg27121462 chr16:89883253 FANCA -0.71 -7.48 -0.56 1.19e-11 Vitiligo; TGCT trans rs916888 0.687 rs199456 chr17:44797919 C/T cg07870213 chr5:140052090 DND1 0.68 8.28 0.6 1.68e-13 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs9399135 0.684 rs1135205 chr6:135281795 C/T cg24558204 chr6:135376177 HBS1L 0.43 4.46 0.37 1.85e-5 Red blood cell count; TGCT cis rs4862307 0.754 rs6846007 chr4:184991604 A/G cg06737308 chr4:185021514 ENPP6 -0.4 -5.72 -0.46 7.56e-8 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs1577917 1.000 rs12200330 chr6:86656653 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.63 -5.13 -0.42 1.07e-6 Response to antipsychotic treatment; TGCT cis rs1865760 0.593 rs3903852 chr6:25915147 G/T cg03517284 chr6:25882590 NA -0.46 -4.62 -0.38 9.46e-6 Height; TGCT cis rs6951245 0.786 rs77943789 chr7:1140158 C/T cg23708337 chr7:1209742 NA 0.54 5.22 0.42 7.2e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs902774 0.515 rs2363635 chr12:53354622 T/C cg16329197 chr12:53359506 NA -0.52 -7.44 -0.56 1.48e-11 Prostate cancer; TGCT cis rs739496 0.579 rs11066054 chr12:112306165 G/T cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs422249 0.512 rs174577 chr11:61604814 A/C cg01500311 chr11:61656094 FADS3 0.32 5.66 0.45 9.89e-8 Trans fatty acid levels; TGCT cis rs12142240 0.698 rs56063031 chr1:46825433 C/T cg00530320 chr1:46809349 NSUN4 0.28 5.79 0.46 5.42e-8 Menopause (age at onset); TGCT cis rs308971 0.518 rs62242085 chr3:12299345 G/T cg23769143 chr3:12200667 SYN2;TIMP4 0.5 4.51 0.38 1.46e-5 Fasting blood insulin (BMI interaction); TGCT cis rs739496 0.563 rs6490294 chr12:112190438 A/C cg10833066 chr12:111807467 FAM109A -0.32 -4.81 -0.4 4.2e-6 Platelet count; TGCT cis rs6964587 0.839 rs11767135 chr7:91551245 T/G cg17063962 chr7:91808500 NA -0.86 -9.28 -0.64 6.82e-16 Breast cancer; TGCT cis rs13191362 0.507 rs2803083 chr6:163111199 A/C cg21926612 chr6:163149169 PACRG;PARK2 0.63 5.67 0.45 9.59e-8 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6674176 0.628 rs4660759 chr1:44432500 C/G cg12908607 chr1:44402522 ARTN -0.72 -8.83 -0.62 8.31e-15 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs117785887 0.536 rs12200649 chr6:146432054 G/C cg06708562 chr6:146285465 SHPRH -0.79 -4.59 -0.38 1.09e-5 Interleukin-17 levels; TGCT cis rs4325129 1.000 rs61821537 chr1:159461560 T/C cg07417683 chr1:159440267 NA -0.45 -4.63 -0.38 9.16e-6 Obesity-related traits; TGCT cis rs11105298 0.891 rs4842654 chr12:89834428 T/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.67 -4.74 -0.39 5.67e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs7618915 0.773 rs10510760 chr3:52650348 G/A cg07507251 chr3:52567010 NT5DC2 0.45 6.02 0.48 1.8e-8 Bipolar disorder; TGCT cis rs1862618 0.802 rs194058 chr5:56188977 G/A cg20203395 chr5:56204925 C5orf35 -0.59 -4.94 -0.41 2.52e-6 Initial pursuit acceleration; TGCT cis rs854765 0.552 rs11078407 chr17:17841083 T/C cg09796270 chr17:17721594 SREBF1 0.24 4.77 0.39 5.04e-6 Total body bone mineral density; TGCT cis rs2032447 0.670 rs198820 chr6:26124243 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.85 -9.07 -0.63 2.22e-15 Intelligence (multi-trait analysis); TGCT cis rs3820928 0.874 rs10178731 chr2:227874232 C/T cg11843606 chr2:227700838 RHBDD1 -0.52 -4.63 -0.38 9.03e-6 Pulmonary function; TGCT cis rs36051895 0.659 rs12343867 chr9:5074189 T/C cg02405213 chr9:5042618 JAK2 -0.77 -10.15 -0.67 5.61e-18 Pediatric autoimmune diseases; TGCT cis rs9473924 0.505 rs7745565 chr6:50860083 A/G cg14470998 chr6:50812995 TFAP2B 1.35 8.39 0.6 9.05e-14 Body mass index; TGCT cis rs910316 0.967 rs119076 chr14:75572419 G/T cg11812906 chr14:75593930 NEK9 -0.72 -6.92 -0.53 2.18e-10 Height; TGCT cis rs208520 0.690 rs4618506 chr6:66756889 A/C cg07460842 chr6:66804631 NA -0.93 -9.76 -0.66 4.84e-17 Exhaled nitric oxide output; TGCT cis rs7666738 0.800 rs11941885 chr4:99072921 A/C cg18180107 chr4:99064573 C4orf37 0.6 5.35 0.43 4e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3020333 0.875 rs2941741 chr6:152008982 G/A cg22157087 chr6:152012887 ESR1 0.2 4.81 0.4 4.24e-6 Total body bone mineral density; TGCT cis rs3008870 0.755 rs1570838 chr1:67403315 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.78 8.29 0.6 1.59e-13 Lymphocyte percentage of white cells; TGCT cis rs6840360 0.571 rs12647566 chr4:152482525 C/T cg17479576 chr4:152424074 FAM160A1 -0.73 -7.94 -0.58 1.03e-12 Intelligence (multi-trait analysis); TGCT cis rs13401104 0.587 rs62190973 chr2:237145231 T/A cg19324714 chr2:237145437 ASB18 0.48 5.03 0.41 1.67e-6 Educational attainment; TGCT cis rs6089829 0.925 rs2277767 chr20:61666937 G/A cg18188782 chr20:61659543 NA 0.44 5.37 0.43 3.73e-7 Prostate cancer (SNP x SNP interaction); TGCT cis rs7582180 0.629 rs4851297 chr2:100949571 G/A cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs3858526 0.920 rs10742832 chr11:5926020 C/G cg13902645 chr11:5959945 NA -0.43 -4.62 -0.38 9.28e-6 DNA methylation (variation); TGCT cis rs3008870 1.000 rs2815348 chr1:67472165 G/C cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs2688608 0.588 rs10128205 chr10:75469648 C/G cg04320760 chr10:75533139 FUT11 -0.4 -6.16 -0.48 9.39e-9 Inflammatory bowel disease; TGCT cis rs9457247 1.000 rs2149091 chr6:167372786 C/T cg23791538 chr6:167370224 RNASET2 0.51 5.12 0.42 1.12e-6 Crohn's disease; TGCT cis rs9549260 0.816 rs9532582 chr13:41251207 A/G cg21288729 chr13:41239152 FOXO1 1.02 10.29 0.68 2.51e-18 Red blood cell count; TGCT cis rs12477438 0.798 rs12477754 chr2:99628073 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs1878931 0.668 rs2074366 chr16:3439676 G/A cg26668626 chr16:3451006 ZNF174;ZNF434 0.98 12.16 0.74 6.83e-23 Body mass index (adult); TGCT cis rs3749237 1.000 rs1317140 chr3:49878652 G/A cg10152585 chr3:50297680 NA 0.53 5.03 0.41 1.69e-6 Resting heart rate; TGCT cis rs950776 0.518 rs55690619 chr15:78833612 A/G cg06917634 chr15:78832804 PSMA4 -0.95 -9.52 -0.65 1.81e-16 Sudden cardiac arrest; TGCT cis rs17221829 0.600 rs3881248 chr11:89362196 T/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs8177253 0.965 rs3811658 chr3:133476852 C/T cg20276088 chr3:133502917 NA -0.24 -4.82 -0.4 4.13e-6 Iron status biomarkers; TGCT cis rs2762353 0.935 rs1185567 chr6:25818588 A/G cg03264133 chr6:25882463 NA -0.53 -5.53 -0.44 1.81e-7 Blood metabolite levels; TGCT cis rs2404602 0.716 rs7164813 chr15:76708066 T/C cg22467129 chr15:76604101 ETFA -0.59 -7.13 -0.54 7.33e-11 Blood metabolite levels; TGCT cis rs861020 0.771 rs674804 chr1:210014603 C/G cg05527609 chr1:210001259 C1orf107 1.05 10.03 0.67 1.07e-17 Orofacial clefts; TGCT cis rs875971 0.862 rs13226170 chr7:65999298 G/A cg11764359 chr7:65958608 NA 0.55 5.08 0.42 1.34e-6 Aortic root size; TGCT cis rs2663905 0.611 rs1509558 chr15:81391244 C/T cg18837035 chr15:81426597 C15orf26 -0.55 -4.75 -0.39 5.42e-6 QT interval (drug interaction); TGCT cis rs587847 0.737 rs1401900 chr15:37585185 A/G cg00216138 chr15:37171175 LOC145845 0.31 4.44 0.37 1.98e-5 Intraocular pressure; TGCT cis rs9911578 1.000 rs12938772 chr17:56776320 T/C cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs8177253 1.000 rs1525892 chr3:133484712 C/T cg08439880 chr3:133502540 NA -0.31 -6.0 -0.47 2.03e-8 Iron status biomarkers; TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg03188948 chr7:1209495 NA 0.48 6.91 0.53 2.31e-10 Longevity;Endometriosis; TGCT cis rs62244186 0.545 rs9284880 chr3:44759389 C/T cg11003573 chr3:44754125 ZNF502 -0.45 -5.08 -0.42 1.32e-6 Depressive symptoms; TGCT trans rs1005277 0.579 rs2474572 chr10:38385316 A/G cg17830980 chr10:43048298 ZNF37B -0.83 -10.65 -0.69 3.3e-19 Extrinsic epigenetic age acceleration; TGCT cis rs1552244 1.000 rs6414438 chr3:10073824 G/C cg00149659 chr3:10157352 C3orf10 0.93 5.98 0.47 2.25e-8 Alzheimer's disease; TGCT cis rs2245008 0.762 rs168800 chr16:83980391 T/C cg27171569 chr16:83987465 OSGIN1 0.46 5.28 0.43 5.58e-7 Pursuit maintenance gain; TGCT cis rs7666738 0.830 rs62318906 chr4:99037110 C/T cg17366294 chr4:99064904 C4orf37 0.73 7.62 0.56 5.65e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs9467711 0.606 rs9393712 chr6:26371000 G/C cg10795676 chr6:26370623 BTN3A2 -0.46 -4.75 -0.39 5.46e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs72781680 0.948 rs113530757 chr2:24142500 G/A cg08917208 chr2:24149416 ATAD2B 0.73 4.51 0.38 1.48e-5 Lymphocyte counts; TGCT cis rs10504229 0.683 rs2873638 chr8:58114593 G/A cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT cis rs13108904 0.901 rs13124847 chr4:1278206 A/G cg13342137 chr4:2252803 MXD4 0.17 4.56 0.38 1.23e-5 Obesity-related traits; TGCT cis rs6545883 0.965 rs9989775 chr2:61761774 A/G cg15711740 chr2:61764176 XPO1 -0.57 -5.23 -0.43 6.89e-7 Tuberculosis; TGCT cis rs933688 1.000 rs332529 chr5:90789470 G/A cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.95 7.97 0.58 8.9e-13 Smoking behavior; TGCT cis rs9910055 0.639 rs7217858 chr17:42254527 T/G cg13607699 chr17:42295918 UBTF 0.59 5.31 0.43 4.88e-7 Total body bone mineral density; TGCT cis rs12230513 0.632 rs59213907 chr12:55728911 A/T cg10672482 chr12:55725839 OR6C3 -0.56 -4.89 -0.4 3.1e-6 Contrast sensitivity; TGCT cis rs6460942 1.000 rs77494477 chr7:12315302 A/T cg06484146 chr7:12443880 VWDE -0.55 -4.56 -0.38 1.22e-5 Coronary artery disease; TGCT cis rs2067615 0.560 rs2044304 chr12:107184363 T/G cg15890332 chr12:107067104 RFX4 0.28 5.61 0.45 1.27e-7 Heart rate; TGCT cis rs17401966 0.522 rs912962 chr1:10348712 G/T cg19773385 chr1:10388646 KIF1B 0.19 4.52 0.38 1.42e-5 Hepatocellular carcinoma; TGCT cis rs2562456 0.917 rs2562466 chr19:21714204 C/T cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs853679 0.517 rs6941992 chr6:28106141 T/C cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Depression; TGCT cis rs57590327 0.716 rs3772891 chr3:81776760 A/G cg07356753 chr3:81810745 GBE1 0.76 6.87 0.53 2.71e-10 Extraversion; TGCT cis rs9325144 0.560 rs11183090 chr12:38662293 G/C cg26384229 chr12:38710491 ALG10B -0.63 -5.92 -0.47 2.9e-8 Morning vs. evening chronotype; TGCT cis rs7937682 0.924 rs12791699 chr11:111505880 T/C cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs6951245 1.000 rs79617366 chr7:1111958 G/C cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs4325129 0.705 rs4418591 chr1:159491355 C/A cg07417683 chr1:159440267 NA 0.37 4.64 0.38 8.54e-6 Obesity-related traits; TGCT cis rs854765 0.603 rs854789 chr17:18026566 C/T cg04398451 chr17:18023971 MYO15A -0.39 -6.89 -0.53 2.53e-10 Total body bone mineral density; TGCT cis rs3785574 0.962 rs8066463 chr17:61818390 A/G cg11494091 chr17:61959527 GH2 0.42 7.46 0.56 1.29e-11 Height; TGCT cis rs644799 0.623 rs17207890 chr11:95490754 C/T cg03916912 chr11:95522834 CEP57;FAM76B 0.75 7.75 0.57 2.9e-12 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1018836 0.923 rs13255452 chr8:91582988 A/G cg16814680 chr8:91681699 NA -0.89 -9.59 -0.65 1.22e-16 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg26119090 chr2:26468346 HADHA;HADHB -0.92 -6.8 -0.52 3.96e-10 Gut microbiome composition (summer); TGCT cis rs7582180 0.607 rs6725052 chr2:100935817 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -4.78 -0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7542091 0.648 rs688464 chr1:209992539 C/T cg23283495 chr1:209979779 IRF6 -0.55 -5.94 -0.47 2.66e-8 Monobrow; TGCT cis rs7647973 0.593 rs7652179 chr3:49808618 T/A cg03034192 chr3:50606346 HEMK1;C3orf18 -0.36 -4.64 -0.38 8.68e-6 Menarche (age at onset); TGCT cis rs34014631 1.000 rs74321972 chr10:103643036 T/C cg22630918 chr10:102748988 C10orf2 0.42 4.94 0.41 2.43e-6 Coronary artery calcification; TGCT cis rs6835098 1.000 rs10027708 chr4:174083116 T/C cg08422745 chr4:174089978 GALNT7 -0.93 -10.95 -0.7 6.1e-20 Dementia and core Alzheimer's disease neuropathologic changes; TGCT cis rs2354432 0.556 rs59180647 chr1:146772062 C/T cg25205988 chr1:146714368 CHD1L -1.34 -6.07 -0.48 1.44e-8 Mitochondrial DNA levels; TGCT cis rs11105298 0.891 rs10858851 chr12:89830870 C/T cg00757033 chr12:89920650 WDR51B 0.33 5.11 0.42 1.16e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs2739330 0.652 rs2000469 chr22:24245292 A/G cg00024416 chr22:24240387 NA -0.25 -4.53 -0.38 1.39e-5 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs4332037 0.950 rs56403963 chr7:1946130 C/G cg10840412 chr1:235813424 GNG4 1.04 8.16 0.59 3.22e-13 Bipolar disorder; TGCT cis rs10504229 0.679 rs78941440 chr8:58052095 A/G cg08280861 chr8:58055591 NA 0.35 5.03 0.41 1.67e-6 Developmental language disorder (linguistic errors); TGCT cis rs1552244 1.000 rs6793396 chr3:10110927 T/C cg00149659 chr3:10157352 C3orf10 0.93 5.99 0.47 2.16e-8 Alzheimer's disease; TGCT cis rs6940638 0.688 rs6921388 chr6:27080205 A/G cg26531700 chr6:26746687 NA -0.56 -4.88 -0.4 3.25e-6 Intelligence (multi-trait analysis); TGCT cis rs8077577 0.895 rs62072465 chr17:18114494 C/G cg09161412 chr17:18057145 MYO15A -0.6 -4.79 -0.4 4.61e-6 Obesity-related traits; TGCT cis rs17767294 0.708 rs72848754 chr6:27878458 T/A cg08851530 chr6:28072375 NA 1.53 7.17 0.54 6.02e-11 Parkinson's disease; TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg08859206 chr1:53392774 SCP2 -0.48 -7.95 -0.58 9.85e-13 Monocyte count; TGCT cis rs9733 0.596 rs7538493 chr1:150655421 T/C cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Tonsillectomy; TGCT cis rs12681288 0.676 rs2600514 chr8:994175 G/A cg04851639 chr8:1020857 NA -0.29 -4.74 -0.39 5.72e-6 Schizophrenia; TGCT cis rs4499344 0.556 rs259230 chr19:33133865 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.82 8.29 0.6 1.58e-13 Mean platelet volume; TGCT cis rs6456156 0.792 rs4710178 chr6:167513532 G/A cg07741184 chr6:167504864 NA 0.22 4.51 0.38 1.48e-5 Primary biliary cholangitis; TGCT cis rs2050392 0.517 rs160017 chr10:30772894 A/G cg13289132 chr10:30722225 MAP3K8 -0.38 -4.48 -0.37 1.7e-5 Inflammatory bowel disease; TGCT cis rs9810089 0.708 rs619605 chr3:136087012 G/C cg12473912 chr3:136751656 NA 0.37 5.2 0.42 7.86e-7 Gestational age at birth (child effect); TGCT cis rs1005224 0.929 rs11625260 chr14:76162293 G/C cg04684003 chr14:76127793 TTLL5;C14orf1 -0.61 -5.64 -0.45 1.07e-7 Large artery stroke; TGCT cis rs509477 0.962 rs723035 chr18:32562845 T/A cg23791764 chr18:32556832 MAPRE2 0.55 4.6 0.38 1.04e-5 Cerebrospinal fluid AB1-42 levels; TGCT cis rs6540559 0.611 rs926347 chr1:209965193 T/C cg23283495 chr1:209979779 IRF6 0.65 5.02 0.41 1.76e-6 Cleft lip with or without cleft palate; TGCT cis rs17376456 0.877 rs7701974 chr5:93311417 C/T cg25358565 chr5:93447407 FAM172A 0.98 8.39 0.6 9.01e-14 Diabetic retinopathy; TGCT cis rs2290416 0.688 rs34892354 chr8:144690648 G/C cg17524265 chr8:144659883 NAPRT1 0.71 5.5 0.44 2.05e-7 Attention deficit hyperactivity disorder; TGCT cis rs9916302 0.904 rs2338755 chr17:37419317 C/T cg15445000 chr17:37608096 MED1 -0.31 -4.59 -0.38 1.06e-5 Glomerular filtration rate (creatinine); TGCT cis rs6665290 0.904 rs12409428 chr1:227189969 T/C cg10327440 chr1:227177885 CDC42BPA -1.0 -20.53 -0.88 1.06e-41 Myeloid white cell count; TGCT cis rs17270561 0.579 rs10456326 chr6:25919662 G/A cg16482183 chr6:26056742 HIST1H1C 0.94 7.28 0.55 3.36e-11 Iron status biomarkers; TGCT cis rs807669 0.868 rs762529 chr22:19170205 C/G cg02655711 chr22:19163373 SLC25A1 0.42 10.01 0.67 1.23e-17 Metabolite levels; TGCT cis rs7666738 0.830 rs11723283 chr4:99001617 C/T cg18180107 chr4:99064573 C4orf37 0.53 4.85 0.4 3.6e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs3764628 1.000 rs72997346 chr19:18762865 G/A cg20098710 chr19:19640075 YJEFN3 -0.46 -4.78 -0.39 4.8e-6 Orofacial clefts; TGCT trans rs4824093 0.610 rs2208023 chr22:50249983 A/G cg09872104 chr7:134855509 C7orf49 -0.9 -7.2 -0.54 5.08e-11 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs35934224 0.783 rs45465601 chr22:19868678 T/C cg11182965 chr22:19864308 TXNRD2 -0.36 -5.11 -0.42 1.16e-6 Glaucoma (primary open-angle); TGCT cis rs1862618 0.641 rs252893 chr5:56224714 T/C cg12311346 chr5:56204834 C5orf35 -0.57 -6.13 -0.48 1.07e-8 Initial pursuit acceleration; TGCT cis rs12580194 0.630 rs60586348 chr12:55745151 A/T cg10672482 chr12:55725839 OR6C3 -0.51 -4.43 -0.37 2.01e-5 Cancer; TGCT cis rs1865760 0.865 rs1541987 chr6:25950397 A/G cg17042849 chr6:26104293 HIST1H4C 0.5 4.63 0.38 9.27e-6 Height; TGCT cis rs10186029 0.676 rs10804213 chr2:213964399 G/A cg08319019 chr2:214017104 IKZF2 0.63 5.79 0.46 5.4e-8 Systemic sclerosis; TGCT cis rs546131 0.928 rs552627 chr11:34826680 G/A cg11058730 chr11:34937778 PDHX;APIP 0.54 4.81 0.4 4.36e-6 Lung disease severity in cystic fibrosis; TGCT cis rs35146811 0.735 rs7811662 chr7:99792608 A/G cg00553149 chr7:99775558 STAG3;GPC2 0.31 4.61 0.38 9.75e-6 Coronary artery disease; TGCT cis rs4713118 0.615 rs9295747 chr6:27736993 G/T cg10876282 chr6:28092338 ZSCAN16 -0.48 -4.97 -0.41 2.16e-6 Parkinson's disease; TGCT cis rs933688 1.000 rs985434 chr5:90744509 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.96 8.25 0.6 1.91e-13 Smoking behavior; TGCT cis rs11190604 0.767 rs10883484 chr10:102174803 G/C cg16342193 chr10:102329863 NA -0.39 -5.05 -0.41 1.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs35306767 0.715 rs11253550 chr10:1028288 C/G cg26597838 chr10:835615 NA 0.58 6.55 0.51 1.35e-9 Eosinophil percentage of granulocytes; TGCT cis rs2404602 0.583 rs2469542 chr15:76557476 A/G cg22467129 chr15:76604101 ETFA 0.64 8.34 0.6 1.2e-13 Blood metabolite levels; TGCT cis rs11098499 0.754 rs1814813 chr4:120258207 G/T cg09307838 chr4:120376055 NA -0.55 -5.52 -0.44 1.93e-7 Corneal astigmatism; TGCT cis rs478304 0.627 rs1073602 chr11:65455386 G/C cg27068330 chr11:65405492 SIPA1 -0.99 -11.36 -0.71 6.13e-21 Acne (severe); TGCT cis rs10479542 1.000 rs10479542 chr5:178981241 T/A cg14820908 chr5:178986412 RUFY1 0.45 4.55 0.38 1.24e-5 Lung cancer; TGCT cis rs1372520 0.766 rs2583961 chr4:90779758 A/G cg14346243 chr4:90757452 SNCA -0.63 -5.28 -0.43 5.7e-7 Neuroticism; TGCT cis rs231513 1.000 rs231499 chr17:41973507 C/T cg26893861 chr17:41843967 DUSP3 0.66 4.91 0.4 2.77e-6 Cognitive function; TGCT cis rs7223966 1.000 rs7214312 chr17:61870863 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.68 0.39 7.5e-6 Hip circumference adjusted for BMI;Body mass index; TGCT trans rs1814175 0.626 rs1722008 chr11:49897676 A/T cg03929089 chr4:120376271 NA -0.7 -7.84 -0.58 1.72e-12 Height; TGCT cis rs7267979 0.966 rs6083818 chr20:25346082 G/A cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7659604 0.702 rs6826506 chr4:122710865 T/G cg20573242 chr4:122745356 CCNA2 0.58 5.1 0.42 1.21e-6 Type 2 diabetes; TGCT cis rs986417 0.748 rs4141684 chr14:61069351 C/T cg27398547 chr14:60952738 C14orf39 1.34 9.87 0.66 2.58e-17 Gut microbiota (bacterial taxa); TGCT cis rs9303542 0.559 rs8079617 chr17:46610028 T/G cg25032089 chr17:46643351 HOXB3 0.58 5.47 0.44 2.38e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs4886920 0.563 rs12900865 chr15:78075910 G/A cg25212270 chr15:78015279 NA -0.23 -4.82 -0.4 4.1e-6 Neuroticism; TGCT cis rs9393692 0.905 rs6908328 chr6:26292855 C/A cg13736514 chr6:26305472 NA -0.39 -5.65 -0.45 1.04e-7 Educational attainment; TGCT cis rs72781680 0.800 rs72790306 chr2:24111311 T/G cg08917208 chr2:24149416 ATAD2B 0.85 5.28 0.43 5.53e-7 Lymphocyte counts; TGCT cis rs10504229 0.728 rs72650853 chr8:58151473 G/A cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs9640161 0.742 rs11983355 chr7:150016697 A/C cg10018233 chr7:150070692 REPIN1 0.33 4.5 0.37 1.57e-5 Blood protein levels;Circulating chemerin levels; TGCT cis rs7924176 0.580 rs12360119 chr10:76015316 G/C cg19889307 chr10:75911429 ADK;AP3M1 -0.47 -4.58 -0.38 1.1e-5 Primary tooth development (time to first tooth eruption);Permanent tooth development;Primary tooth development (number of teeth); TGCT cis rs2880765 0.835 rs28874135 chr15:86031503 G/A cg13263323 chr15:86062960 AKAP13 -0.22 -4.79 -0.4 4.68e-6 Coronary artery disease; TGCT cis rs1670533 1.000 rs10003009 chr4:1050849 G/A cg20887711 chr4:1340912 KIAA1530 0.7 5.66 0.45 9.77e-8 Recombination rate (females); TGCT cis rs4237845 0.680 rs10877033 chr12:58283731 T/C cg02175503 chr12:58329896 NA 0.48 4.77 0.39 5.03e-6 Intelligence (multi-trait analysis); TGCT cis rs12477438 0.798 rs6732579 chr2:99560239 A/T cg15544633 chr2:99771531 LIPT1;TSGA10 -0.8 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs6840360 0.533 rs11099829 chr4:152727299 A/G cg17479576 chr4:152424074 FAM160A1 0.47 4.79 0.4 4.66e-6 Intelligence (multi-trait analysis); TGCT cis rs7829975 0.624 rs7823056 chr8:8382705 A/G cg06636001 chr8:8085503 FLJ10661 0.79 7.59 0.56 6.72e-12 Mood instability; TGCT cis rs55823223 0.646 rs74410877 chr17:73832384 C/T cg08125733 chr17:73851984 WBP2 0.91 5.79 0.46 5.47e-8 Psoriasis; TGCT cis rs28386778 0.765 rs2070680 chr17:61986988 A/G cg22520471 chr17:61851767 DDX42;CCDC47 -0.56 -5.21 -0.42 7.76e-7 Prudent dietary pattern; TGCT cis rs7226408 0.857 rs17567920 chr18:34625813 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs5769765 1.000 rs5769765 chr22:50271176 G/A cg22709217 chr22:50311962 ALG12;CRELD2 1.11 11.76 0.73 6.5e-22 Schizophrenia; TGCT cis rs10804591 0.832 rs9853950 chr3:129336057 A/T cg07730360 chr3:128845626 NA 0.26 5.17 0.42 8.92e-7 Waist-hip ratio;Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Hip circumference adjusted for BMI;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs2486012 1.000 rs1859726 chr1:44396215 C/T cg12908607 chr1:44402522 ARTN -0.68 -5.45 -0.44 2.56e-7 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs2268027 chr3:52766606 G/A cg07507251 chr3:52567010 NT5DC2 0.47 6.75 0.52 5.11e-10 Bipolar disorder; TGCT cis rs4953076 0.573 rs7593987 chr2:44393532 C/T cg00619915 chr2:44497795 NA 0.23 5.11 0.42 1.17e-6 Height; TGCT cis rs1348850 0.608 rs10176632 chr2:178225934 G/T cg22681709 chr2:178499509 PDE11A -0.36 -4.51 -0.38 1.49e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs13256369 0.851 rs13267036 chr8:8566685 G/A cg06671706 chr8:8559999 CLDN23 0.34 4.61 0.38 9.98e-6 Obesity-related traits; TGCT cis rs981844 0.807 rs56053818 chr4:154638126 T/A cg14289246 chr4:154710475 SFRP2 1.0 8.17 0.59 2.94e-13 Response to statins (LDL cholesterol change); TGCT cis rs3796352 0.527 rs11715498 chr3:52943551 G/C cg15956490 chr3:53032818 SFMBT1 0.41 4.59 0.38 1.07e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6831352 0.744 rs2602847 chr4:100025963 T/C cg12011299 chr4:100065546 ADH4 0.4 4.82 0.4 4.07e-6 Alcohol dependence; TGCT cis rs13256369 0.951 rs12679360 chr8:8566269 G/T cg18904891 chr8:8559673 CLDN23 -0.57 -5.55 -0.45 1.64e-7 Obesity-related traits; TGCT cis rs2811893 1.000 rs232872 chr1:59118959 A/G cg26196860 chr1:59745563 NA 0.24 4.44 0.37 1.96e-5 Diabetic retinopathy; TGCT trans rs114540395 0.687 rs75269434 chr10:103473111 G/C cg24140841 chr18:77642911 KCNG2 0.75 6.9 0.53 2.36e-10 Schizophrenia; TGCT cis rs9534288 0.912 rs4942468 chr13:46618290 C/A cg15192986 chr13:46630673 CPB2 -0.49 -6.24 -0.49 6.2e-9 Blood protein levels; TGCT cis rs7584330 0.868 rs2325839 chr2:238386286 T/C cg08992911 chr2:238395768 MLPH 0.61 4.51 0.38 1.51e-5 Prostate cancer; TGCT cis rs9457247 0.967 rs1211447 chr6:167381979 C/T cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs514406 0.825 rs6693210 chr1:53223398 A/G cg24675658 chr1:53192096 ZYG11B 0.71 8.06 0.59 5.58e-13 Monocyte count; TGCT cis rs7666738 0.791 rs11730069 chr4:98945772 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs10789491 1.000 rs35861275 chr1:47171909 A/C cg15501359 chr1:47185051 KIAA0494 -0.83 -8.09 -0.59 4.53e-13 Response to hepatitis C treatment; TGCT cis rs4766566 0.609 rs6490042 chr12:111719060 T/A cg10833066 chr12:111807467 FAM109A 0.36 6.58 0.51 1.18e-9 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs9486719 1.000 rs11153023 chr6:96968525 C/T cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs2806561 0.734 rs11578046 chr1:23425139 G/A cg12483005 chr1:23474871 LUZP1 0.38 4.78 0.39 4.81e-6 Height; TGCT cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg10802521 chr3:52805072 NEK4 -0.71 -8.81 -0.62 9.29e-15 Bipolar disorder; TGCT cis rs12477438 0.520 rs12621007 chr2:99791946 G/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.9 9.33 0.64 5.15e-16 Chronic sinus infection; TGCT cis rs1008375 0.872 rs2315552 chr4:17627294 A/G cg10189774 chr4:17578691 LAP3 0.56 5.03 0.41 1.67e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.683 rs17194529 chr8:58105647 A/G cg08280861 chr8:58055591 NA 0.54 6.51 0.5 1.66e-9 Developmental language disorder (linguistic errors); TGCT cis rs151997 0.629 rs152808 chr5:50207382 G/C cg06027927 chr5:50259733 NA 0.56 5.64 0.45 1.11e-7 Callous-unemotional behaviour; TGCT cis rs9372253 0.645 rs7753212 chr6:110700229 T/C cg01119278 chr6:110721349 DDO -0.3 -4.62 -0.38 9.64e-6 Platelet distribution width; TGCT cis rs10927875 0.631 rs945418 chr1:16344730 T/C cg21385522 chr1:16154831 NA 0.62 6.41 0.5 2.76e-9 Dilated cardiomyopathy; TGCT cis rs1843834 0.505 rs4674911 chr2:225345254 A/G cg22455342 chr2:225449267 CUL3 1.02 10.7 0.69 2.53e-19 IgE levels in asthmatics (D.p. specific); TGCT cis rs4851254 0.618 rs12996621 chr2:100646137 A/G cg07810366 chr2:100720526 AFF3 -0.47 -4.81 -0.4 4.37e-6 Intelligence (multi-trait analysis); TGCT cis rs7089973 0.585 rs7907837 chr10:116610690 G/T cg03647239 chr10:116582469 FAM160B1 0.61 5.86 0.47 3.87e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs3796352 1.000 rs71617204 chr3:53042951 G/A cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT trans rs561341 1.000 rs2344312 chr17:30243583 G/T cg20587970 chr11:113659929 NA -0.88 -10.79 -0.7 1.49e-19 Hip circumference adjusted for BMI; TGCT cis rs4886238 0.517 rs9528165 chr13:61176836 G/C cg23734418 chr13:61221316 NA -0.29 -5.39 -0.44 3.37e-7 Menopause (age at onset); TGCT cis rs7666738 0.830 rs7662199 chr4:99019766 G/A cg05340658 chr4:99064831 C4orf37 0.49 5.62 0.45 1.18e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs6750047 0.771 rs2855658 chr2:38296890 T/C cg07380506 chr2:38303506 CYP1B1 0.66 6.01 0.47 1.94e-8 Cutaneous malignant melanoma;Melanoma; TGCT cis rs910316 0.763 rs2080201 chr14:75629972 C/T cg08847533 chr14:75593920 NEK9 -0.83 -8.23 -0.59 2.13e-13 Height; TGCT cis rs933688 0.941 rs2887007 chr5:90740531 A/T cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.93 8.39 0.6 9.04e-14 Smoking behavior; TGCT cis rs13191362 1.000 rs13190742 chr6:163008758 G/A cg21926612 chr6:163149169 PACRG;PARK2 0.69 5.62 0.45 1.21e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6674176 0.597 rs12127737 chr1:44402565 G/A cg12908607 chr1:44402522 ARTN -0.75 -9.6 -0.65 1.15e-16 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs1878931 0.580 rs4578649 chr16:3407258 C/T cg26668626 chr16:3451006 ZNF174;ZNF434 -0.91 -10.18 -0.67 4.65e-18 Body mass index (adult); TGCT cis rs17376456 0.569 rs6895356 chr5:93060781 A/G cg25358565 chr5:93447407 FAM172A 0.66 5.56 0.45 1.57e-7 Diabetic retinopathy; TGCT cis rs13118159 0.550 rs2336081 chr4:1350322 A/G cg05025164 chr4:1340916 KIAA1530 -0.76 -6.84 -0.52 3.13e-10 Longevity; TGCT cis rs3960554 0.808 rs57721466 chr7:75710049 C/T cg17325771 chr7:75508891 RHBDD2 -0.54 -4.63 -0.38 8.97e-6 Eotaxin levels; TGCT cis rs12908161 1.000 rs11637142 chr15:85295927 A/G cg17173187 chr15:85201210 NMB 0.57 6.35 0.5 3.65e-9 Schizophrenia; TGCT cis rs7666738 0.546 rs34159897 chr4:98787367 T/C cg05340658 chr4:99064831 C4orf37 0.51 5.65 0.45 1.03e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1499614 1.000 rs1638731 chr7:66144679 C/T cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs7474896 0.559 rs10740949 chr10:37978435 A/G cg13720705 chr10:37990370 NA 0.34 5.0 0.41 1.89e-6 Obesity (extreme); TGCT cis rs7267979 0.934 rs2257464 chr20:25265872 C/T cg03522245 chr20:25566470 NINL 0.63 6.72 0.52 5.91e-10 Liver enzyme levels (alkaline phosphatase); TGCT trans rs8073060 0.586 rs225250 chr17:33941963 A/G cg19694781 chr19:47549865 TMEM160 -0.61 -13.7 -0.78 1.39e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs6484504 0.600 rs366758 chr11:31222499 A/C cg26647111 chr11:31128758 NA -0.34 -4.62 -0.38 9.36e-6 Red blood cell count; TGCT trans rs931812 0.825 rs35472498 chr8:101894167 G/A cg20993868 chr7:22813445 NA 0.42 9.03 0.63 2.75e-15 Attention deficit hyperactivity disorder and conduct disorder; TGCT cis rs6815814 0.898 rs73236616 chr4:38789675 G/A cg02016764 chr4:38805732 TLR1 -0.34 -5.4 -0.44 3.2e-7 Breast cancer; TGCT cis rs453301 0.686 rs3895823 chr8:8873646 T/C cg15556689 chr8:8085844 FLJ10661 -0.64 -5.29 -0.43 5.37e-7 Joint mobility (Beighton score); TGCT cis rs12681288 0.676 rs7011999 chr8:1008446 A/G cg04851639 chr8:1020857 NA -0.31 -5.17 -0.42 8.94e-7 Schizophrenia; TGCT cis rs35883536 0.647 rs59667512 chr1:101046712 C/T cg06223162 chr1:101003688 GPR88 -0.41 -7.64 -0.57 5.04e-12 Monocyte count; TGCT cis rs172166 0.694 rs1631552 chr6:28089699 C/A cg10876282 chr6:28092338 ZSCAN16 0.51 4.69 0.39 6.99e-6 Cardiac Troponin-T levels; TGCT cis rs7312933 0.703 rs7957471 chr12:42545591 G/T cg19980929 chr12:42632907 YAF2 0.47 6.46 0.5 2.13e-9 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs3008870 0.755 rs2815364 chr1:67498384 C/T cg08660285 chr1:67390436 MIER1;WDR78 0.8 8.48 0.61 5.61e-14 Lymphocyte percentage of white cells; TGCT cis rs7044106 0.762 rs4837790 chr9:123446325 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.6 6.34 0.49 3.94e-9 Hip circumference adjusted for BMI; TGCT cis rs797680 0.796 rs797661 chr1:93687091 G/T cg17826107 chr1:92977322 EVI5 0.24 5.29 0.43 5.47e-7 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs36051895 0.589 rs7850294 chr9:5191128 C/T cg02405213 chr9:5042618 JAK2 0.72 9.26 0.64 7.77e-16 Pediatric autoimmune diseases; TGCT cis rs2836974 0.966 rs7283516 chr21:40690537 A/G cg17971929 chr21:40555470 PSMG1 0.96 8.52 0.61 4.51e-14 Cognitive function; TGCT cis rs9486715 0.867 rs12207471 chr6:96963782 A/G cg06623918 chr6:96969491 KIAA0776 1.1 15.44 0.81 1.17e-30 Headache; TGCT cis rs10782582 0.609 rs1498311 chr1:76254726 A/C cg03433033 chr1:76189801 ACADM 0.47 4.75 0.39 5.62e-6 Daytime sleep phenotypes; TGCT cis rs72945132 0.660 rs7121703 chr11:70140296 C/T cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs7666738 0.830 rs116103936 chr4:98954531 T/C cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7178572 0.568 rs4886866 chr15:77696166 A/T cg15453836 chr15:77711506 NA -0.42 -4.81 -0.4 4.28e-6 Type 2 diabetes; TGCT cis rs514406 0.861 rs551435 chr1:53260537 G/T cg22166914 chr1:53195759 ZYG11B -0.42 -7.46 -0.56 1.33e-11 Monocyte count; TGCT cis rs3862260 0.509 rs10754416 chr1:120163531 A/G cg11530693 chr1:120165357 ZNF697 0.2 4.54 0.38 1.3e-5 Systemic lupus erythematosus; TGCT cis rs4665809 0.556 rs4665322 chr2:26434605 C/G cg26119090 chr2:26468346 HADHA;HADHB -0.98 -7.22 -0.54 4.68e-11 Gut microbiome composition (summer); TGCT cis rs12478296 1.000 rs4973685 chr2:243019089 A/C cg06360820 chr2:242988706 NA -0.83 -5.68 -0.45 9.26e-8 Obesity-related traits; TGCT cis rs9291683 0.507 rs6849273 chr4:10021595 C/T cg11266682 chr4:10021025 SLC2A9 0.64 8.47 0.61 6.02e-14 Bone mineral density; TGCT cis rs9634489 0.502 rs17189979 chr13:97121087 G/A cg11411106 chr13:97107445 HS6ST3 0.26 4.51 0.38 1.51e-5 Body mass index; TGCT cis rs9868809 0.505 rs56735597 chr3:48765168 A/G cg00383909 chr3:49044727 WDR6 1.26 6.32 0.49 4.2e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs4523957 0.583 rs7212589 chr17:2042393 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.58 -0.38 1.13e-5 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs17221829 0.720 rs10765237 chr11:89453598 T/G cg02982614 chr11:89391479 FOLH1B -0.29 -4.95 -0.41 2.4e-6 Anxiety in major depressive disorder; TGCT cis rs12142240 0.698 rs6703374 chr1:46862332 C/G cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs7772486 0.840 rs2777478 chr6:146309117 T/C cg13319975 chr6:146136371 FBXO30 -0.53 -4.68 -0.39 7.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7178572 0.568 rs1565757 chr15:77657682 C/T cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs2795502 1.000 rs2185717 chr10:43343875 G/A cg20628663 chr10:43360327 NA 0.43 6.22 0.49 7.01e-9 Blood protein levels; TGCT cis rs3008870 1.000 rs2182143 chr1:67378936 T/C cg08660285 chr1:67390436 MIER1;WDR78 1.1 12.08 0.74 1.11e-22 Lymphocyte percentage of white cells; TGCT cis rs2072499 0.966 rs2984615 chr1:156165317 G/C cg24450063 chr1:156163899 SLC25A44 1.2 18.21 0.85 7.43e-37 Testicular germ cell tumor; TGCT cis rs734999 0.588 rs2985859 chr1:2532416 T/C cg18854424 chr1:2615690 NA -0.46 -5.28 -0.43 5.53e-7 Ulcerative colitis; TGCT cis rs6429082 0.715 rs2153204 chr1:235580382 A/G cg26050004 chr1:235667680 B3GALNT2 -0.57 -5.03 -0.41 1.7e-6 Adiposity; TGCT cis rs2836974 0.897 rs34599551 chr21:40594898 C/A cg06238570 chr21:40685208 BRWD1 0.67 6.12 0.48 1.14e-8 Cognitive function; TGCT cis rs3733585 0.699 rs7677710 chr4:9969517 T/G cg00071950 chr4:10020882 SLC2A9 -0.57 -6.83 -0.52 3.47e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs7811142 1.000 rs2406253 chr7:100077273 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs17345786 0.861 rs74768235 chr3:101142821 T/C cg11279151 chr3:101281821 RG9MTD1 -0.4 -8.39 -0.6 9.01e-14 Colonoscopy-negative controls vs population controls; TGCT cis rs4849845 0.612 rs3806491 chr2:121008675 G/A cg24070213 chr2:121070622 NA 0.35 4.69 0.39 6.98e-6 Mean platelet volume; TGCT cis rs3125734 0.633 rs1873685 chr10:64032126 C/T cg19640130 chr10:64028056 RTKN2 -0.4 -5.2 -0.42 8.01e-7 Rheumatoid arthritis; TGCT cis rs2354432 0.825 rs10900347 chr1:146800107 G/C cg25205988 chr1:146714368 CHD1L 1.28 9.92 0.67 1.94e-17 Mitochondrial DNA levels; TGCT cis rs1008375 0.966 rs6449325 chr4:17699509 C/T cg18681998 chr4:17616180 MED28 -0.72 -6.85 -0.52 3.1e-10 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs700651 0.789 rs6715070 chr2:198898265 A/G cg00792783 chr2:198669748 PLCL1 -0.59 -5.34 -0.43 4.33e-7 Intracranial aneurysm; TGCT cis rs6724607 1.000 rs6724607 chr2:191466532 C/T cg11845111 chr2:191398756 TMEM194B 0.35 5.44 0.44 2.76e-7 Pulse pressure; TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg25767906 chr1:53392781 SCP2 -0.55 -6.64 -0.51 8.87e-10 Monocyte count; TGCT cis rs2153535 0.580 rs7453115 chr6:8447261 A/G cg07606381 chr6:8435919 SLC35B3 0.53 5.02 0.41 1.79e-6 Motion sickness; TGCT cis rs11577318 0.853 rs4471263 chr1:26622700 C/T cg04990556 chr1:26633338 UBXN11 -0.61 -5.63 -0.45 1.17e-7 Granulocyte percentage of myeloid white cells; TGCT cis rs2841277 0.770 rs10149193 chr14:105403474 C/T cg19901468 chr14:105411992 AHNAK2 -0.28 -5.93 -0.47 2.77e-8 Rheumatoid arthritis; TGCT cis rs7523273 0.565 rs1998538 chr1:207886487 C/T cg22525895 chr1:207977042 MIR29B2 -0.36 -5.89 -0.47 3.47e-8 Schizophrenia; TGCT cis rs1799949 1.000 rs34534709 chr17:41302940 C/G cg10047753 chr17:41438598 NA 0.97 9.99 0.67 1.37e-17 Menopause (age at onset); TGCT cis rs35883536 0.846 rs964905 chr1:101087131 T/C cg06223162 chr1:101003688 GPR88 -0.33 -5.34 -0.43 4.33e-7 Monocyte count; TGCT cis rs10504229 0.683 rs56058640 chr8:58128862 C/T cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs734999 0.505 rs4445406 chr1:2539400 T/C cg18854424 chr1:2615690 NA 0.44 5.1 0.42 1.23e-6 Ulcerative colitis; TGCT cis rs1799949 0.628 rs4474733 chr17:41433660 G/T cg05368731 chr17:41323189 NBR1 1.01 9.09 0.63 1.94e-15 Menopause (age at onset); TGCT cis rs13108904 0.870 rs3775092 chr4:1240962 C/G cg05665937 chr4:1216051 CTBP1 0.27 5.34 0.43 4.28e-7 Obesity-related traits; TGCT cis rs8070128 0.601 rs8080602 chr17:17954728 G/C cg09796270 chr17:17721594 SREBF1 -0.24 -4.7 -0.39 6.8e-6 Total body bone mineral density; TGCT cis rs2013441 1.000 rs2013441 chr17:20023099 G/A cg18979559 chr17:20280153 CCDC144C 0.47 4.88 0.4 3.16e-6 Obesity-related traits; TGCT cis rs875971 1.000 rs12533997 chr7:65965377 A/G cg11764359 chr7:65958608 NA 0.59 5.29 0.43 5.45e-7 Aortic root size; TGCT cis rs4242434 0.854 rs3064 chr8:22451688 C/G cg03733263 chr8:22462867 KIAA1967 -1.12 -17.66 -0.85 1.22e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs317689 0.581 rs315132 chr12:69761996 G/C cg11871910 chr12:69753446 YEATS4 0.58 5.18 0.42 8.72e-7 Response to diuretic therapy; TGCT cis rs6840360 0.642 rs7680013 chr4:152409477 A/C cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.82e-9 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.576 rs246024 chr5:140333952 C/T cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs12145833 0.596 rs12123491 chr1:243297924 C/G cg02356786 chr1:243265016 LOC731275 0.52 4.58 0.38 1.12e-5 Obesity (early onset extreme); TGCT cis rs9611565 0.592 rs5751101 chr22:41828111 C/T cg17554472 chr22:41940697 POLR3H 0.49 5.23 0.42 7.08e-7 Vitiligo; TGCT cis rs1348850 0.632 rs12616288 chr2:178503813 G/T cg22681709 chr2:178499509 PDE11A -0.53 -6.51 -0.5 1.69e-9 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs10791097 0.694 rs10894275 chr11:130756251 C/T cg05962950 chr11:130786565 SNX19 0.9 11.06 0.7 3.32e-20 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7914558 1.000 rs12780843 chr10:104769335 G/C cg15744005 chr10:104629667 AS3MT -0.4 -4.88 -0.4 3.25e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10504229 0.683 rs16921843 chr8:58113338 T/C cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs4803468 0.967 rs1077856 chr19:41885221 T/C cg09537434 chr19:41945824 ATP5SL -0.85 -9.13 -0.63 1.57e-15 Height; TGCT cis rs595982 0.527 rs73061659 chr19:49373556 G/A cg21252483 chr19:49399788 TULP2 -0.42 -6.36 -0.5 3.58e-9 Red cell distribution width; TGCT cis rs7191439 0.722 rs6500491 chr16:88783521 T/C cg27087555 chr16:88793112 FAM38A -0.54 -5.86 -0.47 3.88e-8 Plateletcrit; TGCT cis rs4713118 0.539 rs200951 chr6:27835930 A/G cg18675097 chr6:28227127 NKAPL -0.35 -4.54 -0.38 1.34e-5 Parkinson's disease; TGCT cis rs7666738 0.546 rs11727151 chr4:98837353 A/C cg17366294 chr4:99064904 C4orf37 0.65 6.03 0.48 1.73e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7772486 0.875 rs2748501 chr6:146312258 G/A cg23711669 chr6:146136114 FBXO30 0.89 9.37 0.64 4.24e-16 Lobe attachment (rater-scored or self-reported); TGCT cis rs6671200 0.920 rs35403759 chr1:95702890 C/T cg26537280 chr1:95699037 RWDD3 0.7 5.55 0.45 1.62e-7 Stearic acid (18:0) levels; TGCT cis rs10504229 0.683 rs11774847 chr8:58140775 T/A cg08280861 chr8:58055591 NA 0.52 5.97 0.47 2.35e-8 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs67384205 chr8:58180348 C/G cg21724239 chr8:58056113 NA 0.38 5.18 0.42 8.82e-7 Developmental language disorder (linguistic errors); TGCT cis rs6939532 0.522 rs9358933 chr6:26363688 C/T cg05738196 chr6:26577821 NA -0.53 -5.03 -0.41 1.68e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7178615 1 rs7178615 chr15:66869072 A/G cg08479319 chr15:66648941 TIPIN -0.5 -4.56 -0.38 1.2e-5 Diastolic blood pressure; TGCT cis rs314370 1.000 rs314370 chr7:100453208 T/C cg10426581 chr7:100472382 SRRT 0.98 10.52 0.69 7e-19 Resting heart rate; TGCT cis rs3806843 0.576 rs246037 chr5:140331846 C/T cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs1538970 0.748 rs11211137 chr1:46013892 T/A cg05343316 chr1:45956843 TESK2 0.72 5.48 0.44 2.26e-7 Platelet count; TGCT cis rs7954584 0.567 rs7132055 chr12:122346034 A/G cg21171335 chr12:122356390 WDR66 -0.67 -6.74 -0.52 5.3e-10 Mean corpuscular volume; TGCT cis rs10883723 0.810 rs12265877 chr10:104247247 C/G cg05855489 chr10:104503620 C10orf26 -0.56 -4.91 -0.4 2.81e-6 Allergic disease (asthma, hay fever or eczema); TGCT cis rs763121 0.853 rs3788544 chr22:39064966 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.57 0.56 7.47e-12 Menopause (age at onset); TGCT cis rs12711979 0.509 rs10181286 chr2:3824567 G/A cg17052675 chr2:3827356 NA -0.55 -12.72 -0.75 3.04e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7635838 0.859 rs6784883 chr3:11444453 G/A cg00170343 chr3:11313890 ATG7 0.66 6.25 0.49 5.91e-9 HDL cholesterol; TGCT cis rs853679 0.513 rs9468296 chr6:28113730 A/G cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs72634258 0.554 rs17374292 chr1:7881234 C/T cg26816564 chr1:7831052 VAMP3 0.87 6.44 0.5 2.34e-9 Inflammatory bowel disease; TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs2964802 0.505 rs7728436 chr5:10814464 T/A cg14521931 chr5:10832172 NA -0.28 -4.61 -0.38 9.72e-6 Major depressive disorder;Recurrent major depressive disorder; TGCT cis rs700590 0.723 rs167345 chr5:88118858 A/G cg22951263 chr5:87985283 NA 0.56 5.4 0.44 3.27e-7 Educational attainment (years of education); TGCT cis rs9993613 0.875 rs13104467 chr4:73455382 C/T cg15102770 chr4:73434591 ADAMTS3 0.52 4.71 0.39 6.4e-6 Hip circumference adjusted for BMI;Height; TGCT cis rs11711311 1.000 rs9288982 chr3:113470149 A/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -6.76 -0.52 4.88e-10 IgG glycosylation; TGCT cis rs17433780 0.857 rs12144445 chr1:89465238 C/T cg09516651 chr1:89888402 LOC400759 0.32 5.89 0.47 3.35e-8 Carotid intima media thickness; TGCT cis rs11096990 0.634 rs2276888 chr4:39279907 C/T cg20847110 chr4:39482781 LOC401127 -0.17 -4.89 -0.4 3.03e-6 Cognitive function; TGCT trans rs7618501 0.633 rs3774733 chr3:50037123 C/G cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.4 0.65 3.49e-16 Intelligence (multi-trait analysis); TGCT cis rs10540 1.000 rs61876336 chr11:489537 C/T cg03352830 chr11:487213 PTDSS2 0.26 4.57 0.38 1.16e-5 Body mass index; TGCT cis rs951366 0.789 rs823097 chr1:205681370 G/A cg14893161 chr1:205819251 PM20D1 0.52 7.1 0.54 8.73e-11 Menarche (age at onset); TGCT cis rs6460942 0.818 rs73299043 chr7:12251595 C/G cg06484146 chr7:12443880 VWDE -0.58 -4.99 -0.41 2.02e-6 Coronary artery disease; TGCT cis rs6589563 0.609 rs12285095 chr11:116658031 T/G cg20660624 chr11:117307972 DSCAML1 -0.43 -5.2 -0.42 8.01e-7 Eosinophil counts; TGCT cis rs7647973 1.000 rs9860055 chr3:49506900 C/T cg05785598 chr3:49045655 WDR6 -0.38 -4.5 -0.37 1.57e-5 Menarche (age at onset); TGCT cis rs6964587 0.773 rs59242586 chr7:91918145 A/G cg17063962 chr7:91808500 NA 0.85 8.52 0.61 4.45e-14 Breast cancer; TGCT cis rs17221829 0.703 rs11018682 chr11:89364451 A/C cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs1056107 0.572 rs10981383 chr9:115156785 A/G cg02332936 chr9:115140584 NA -0.26 -4.6 -0.38 1.02e-5 Colorectal cancer; TGCT cis rs624899 0.655 rs8109248 chr19:11641375 C/T cg15237152 chr19:11649631 CNN1 0.48 5.22 0.42 7.29e-7 Presence of antiphospholipid antibodies; TGCT cis rs2455799 0.552 rs2470540 chr3:15718652 T/A cg16303742 chr3:15540471 COLQ -0.26 -4.93 -0.4 2.58e-6 Mean platelet volume; TGCT cis rs587847 0.708 rs4924149 chr15:37633075 C/T cg00216138 chr15:37171175 LOC145845 0.32 4.74 0.39 5.71e-6 Intraocular pressure; TGCT cis rs514406 0.893 rs479569 chr1:53352407 C/T cg25767906 chr1:53392781 SCP2 -0.55 -6.57 -0.51 1.28e-9 Monocyte count; TGCT cis rs1981331 1.000 rs79694455 chr21:47983979 C/T cg23283320 chr21:48055893 PRMT2 1.29 5.89 0.47 3.42e-8 Cerebrospinal fluid t-tau:AB1-42 ratio; TGCT cis rs7264396 0.635 rs2064724 chr20:34522520 T/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.3 -5.31 -0.43 4.87e-7 Total cholesterol levels; TGCT cis rs6700896 0.500 rs57941031 chr1:66087742 G/T cg14976592 chr1:65886160 LEPROT;LEPR 0.59 4.56 0.38 1.22e-5 C-reactive protein;Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs11190604 1.000 rs11190551 chr10:102204734 A/G cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1552244 1.000 rs13433680 chr3:10136390 T/A cg00149659 chr3:10157352 C3orf10 0.93 5.73 0.46 7.25e-8 Alzheimer's disease; TGCT trans rs1814175 0.645 rs10444311 chr11:49986906 A/G cg11707556 chr5:10655725 ANKRD33B -0.44 -10.67 -0.69 2.92e-19 Height; TGCT cis rs6762 0.719 rs28655651 chr11:837121 G/C cg16425592 chr11:842748 TSPAN4;POLR2L -0.46 -4.66 -0.39 7.94e-6 Mean platelet volume; TGCT cis rs1552244 0.572 rs2054478 chr3:10172211 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.45 -5.49 -0.44 2.22e-7 Alzheimer's disease; TGCT cis rs2456568 0.741 rs2102332 chr11:93635281 G/T cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.07e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs763121 0.853 rs2284073 chr22:39105948 T/C cg06022373 chr22:39101656 GTPBP1 0.78 8.1 0.59 4.34e-13 Menopause (age at onset); TGCT cis rs7954584 0.635 rs7313252 chr12:122347600 G/A cg22618164 chr12:122356400 WDR66 0.59 6.03 0.48 1.71e-8 Mean corpuscular volume; TGCT cis rs2224391 0.628 rs2773310 chr6:5250828 C/T cg09085698 chr6:5261316 LYRM4;FARS2 -1.04 -6.69 -0.51 6.87e-10 Height; TGCT cis rs6546537 0.911 rs62133968 chr2:69891910 C/T cg10773587 chr2:69614142 GFPT1 -0.82 -7.07 -0.54 1.01e-10 Serum thyroid-stimulating hormone levels; TGCT cis rs7923609 0.841 rs7920036 chr10:65293860 T/C cg08743896 chr10:65200160 JMJD1C -0.33 -4.48 -0.37 1.69e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs9393692 0.875 rs12526215 chr6:26262916 T/C cg05868516 chr6:26286170 HIST1H4H 0.63 5.91 0.47 3.1e-8 Educational attainment; TGCT cis rs1577917 1.000 rs1577917 chr6:86691940 C/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.62 -5.06 -0.41 1.46e-6 Response to antipsychotic treatment; TGCT cis rs10782582 0.593 rs77208152 chr1:76124255 T/C cg22875332 chr1:76189707 ACADM -0.54 -6.36 -0.5 3.61e-9 Daytime sleep phenotypes; TGCT cis rs7618915 0.547 rs12496634 chr3:52709259 A/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs8020441 1.000 rs68120925 chr14:51169258 C/A cg04730355 chr14:51134070 SAV1 0.73 6.02 0.48 1.84e-8 Cognitive performance; TGCT cis rs617219 0.574 rs7732681 chr5:78595246 C/T cg23514016 chr5:78407564 BHMT -0.3 -4.51 -0.38 1.49e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs16867321 0.950 rs9677293 chr2:181499459 C/G cg23363182 chr2:181467187 NA -0.38 -5.55 -0.45 1.62e-7 Obesity; TGCT cis rs13108904 0.934 rs35201724 chr4:1310717 C/G cg03303774 chr4:1407052 NA 0.35 5.37 0.43 3.78e-7 Obesity-related traits; TGCT cis rs9916302 0.904 rs68178216 chr17:37526241 A/C cg07936489 chr17:37558343 FBXL20 0.63 4.91 0.4 2.83e-6 Glomerular filtration rate (creatinine); TGCT cis rs858239 0.600 rs6956595 chr7:23134256 A/G cg05602783 chr7:23145260 KLHL7 -0.58 -4.85 -0.4 3.68e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs7698623 0.850 rs6532021 chr4:88769661 C/G cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs60871478 0.730 rs73042471 chr7:927762 G/A cg00475322 chr7:917719 C7orf20 0.52 4.99 0.41 2.03e-6 Cerebrospinal P-tau181p levels; TGCT cis rs9646954 0.542 rs4149512 chr2:101022886 C/T cg08017756 chr2:100939284 LONRF2 -0.3 -4.73 -0.39 5.95e-6 Intelligence (multi-trait analysis); TGCT cis rs6582630 0.519 rs12366667 chr12:38332632 C/T cg26384229 chr12:38710491 ALG10B 0.79 6.88 0.53 2.65e-10 Drug-induced liver injury (flucloxacillin); TGCT cis rs7666738 0.925 rs2865952 chr4:99040305 C/T cg05340658 chr4:99064831 C4orf37 0.48 4.68 0.39 7.33e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs5760092 0.755 rs11090298 chr22:24262061 G/A cg02953382 chr22:24373134 LOC391322 0.84 7.25 0.55 4.02e-11 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs10744422 0.686 rs4424710 chr12:123293302 T/G cg18912006 chr12:123335444 HIP1R 0.56 4.78 0.39 4.84e-6 Schizophrenia; TGCT cis rs79839061 0.656 rs28662837 chr4:879776 G/A cg15843217 chr4:699224 PCGF3 -0.56 -4.52 -0.38 1.42e-5 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.520 rs8130240 chr21:40538108 G/A cg11644478 chr21:40555479 PSMG1 -0.52 -4.83 -0.4 3.98e-6 Menarche (age at onset); TGCT cis rs7100689 0.646 rs1340376 chr10:82128963 A/G cg01528321 chr10:82214614 TSPAN14 0.8 7.76 0.57 2.7e-12 Post bronchodilator FEV1; TGCT cis rs8072100 0.967 rs4794001 chr17:45720849 T/C cg08085267 chr17:45401833 C17orf57 -0.42 -4.6 -0.38 1.04e-5 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4233949 0.535 rs7605902 chr2:54620459 A/C cg14634210 chr2:54682758 SPTBN1 0.51 4.62 0.38 9.38e-6 Bone mineral density; TGCT cis rs7551222 0.716 rs10900601 chr1:204572050 A/G cg09150239 chr1:204347429 NA 0.51 4.73 0.39 6.03e-6 Schizophrenia; TGCT cis rs9467773 0.596 rs2451751 chr6:26646714 T/C cg02458000 chr6:26745757 NA 0.51 4.59 0.38 1.08e-5 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs17805332 chr8:58169798 A/G cg08280861 chr8:58055591 NA 0.36 4.89 0.4 3.03e-6 Developmental language disorder (linguistic errors); TGCT cis rs7918232 0.830 rs9833 chr10:27400861 G/A cg14442939 chr10:27389572 ANKRD26 0.71 5.33 0.43 4.45e-7 Breast cancer; TGCT cis rs12477438 0.765 rs62154861 chr2:99590235 T/C cg15544633 chr2:99771531 LIPT1;TSGA10 -0.87 -8.79 -0.62 1.04e-14 Chronic sinus infection; TGCT cis rs7666738 0.830 rs7664305 chr4:99037691 G/A cg18180107 chr4:99064573 C4orf37 0.58 5.39 0.44 3.47e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs8067545 0.750 rs11871651 chr17:19997425 T/C cg13482628 chr17:19912719 NA 0.52 4.48 0.37 1.67e-5 Schizophrenia; TGCT cis rs2050392 1.000 rs2265185 chr10:30691777 A/C cg18806716 chr10:30721971 MAP3K8 -0.44 -5.18 -0.42 8.82e-7 Inflammatory bowel disease; TGCT cis rs4689388 0.853 rs6817447 chr4:6286847 G/T cg00701064 chr4:6280414 WFS1 0.46 6.15 0.48 9.62e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs4665809 1.000 rs6546728 chr2:26276531 G/C cg27170947 chr2:26402098 FAM59B -0.4 -4.63 -0.38 8.93e-6 Gut microbiome composition (summer); TGCT cis rs67478160 0.643 rs6575997 chr14:104228546 C/T cg26031613 chr14:104095156 KLC1 0.6 6.24 0.49 6.3e-9 Schizophrenia; TGCT cis rs477895 0.838 rs72922039 chr11:64013116 A/C cg04317338 chr11:64019027 PLCB3 0.81 6.94 0.53 1.98e-10 Mean platelet volume; TGCT cis rs2153535 0.580 rs9406169 chr6:8509470 A/T cg23788917 chr6:8435910 SLC35B3 0.57 5.3 0.43 5.17e-7 Motion sickness; TGCT cis rs10782582 0.609 rs5745394 chr1:76311731 G/A cg05598546 chr1:76251766 SNORD45C;RABGGTB 0.52 4.53 0.38 1.37e-5 Daytime sleep phenotypes; TGCT cis rs28386778 0.735 rs2727336 chr17:61991965 G/C cg25654072 chr17:61904446 PSMC5;FTSJ3 -0.49 -4.61 -0.38 9.67e-6 Prudent dietary pattern; TGCT cis rs1933488 0.898 rs6557261 chr6:153415368 G/A cg24028809 chr6:153414101 RGS17 0.21 4.67 0.39 7.69e-6 Prostate cancer; TGCT cis rs67311347 0.544 rs6599088 chr3:40329288 T/C cg13683864 chr3:40499215 RPL14 -0.78 -7.45 -0.56 1.42e-11 Renal cell carcinoma; TGCT trans rs3107575 0.572 rs73169366 chr3:165320307 C/T cg04770195 chr16:53114571 CHD9 1.14 6.64 0.51 8.63e-10 Morning vs. evening chronotype; TGCT cis rs2880765 0.805 rs34598679 chr15:86042205 G/A cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs4820539 0.902 rs9612237 chr22:23472954 T/C cg14186256 chr22:23484241 RTDR1 0.98 12.28 0.74 3.5e-23 Bone mineral density; TGCT cis rs6951245 0.935 rs61753396 chr7:1105372 A/G cg23708337 chr7:1209742 NA 0.6 5.57 0.45 1.53e-7 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs12541335 0.615 rs4872464 chr8:22153381 G/A cg18135555 chr8:22132992 PIWIL2 0.29 5.62 0.45 1.22e-7 Hypertriglyceridemia; TGCT cis rs12693043 0.764 rs13006261 chr2:175404695 G/A cg11778734 chr2:175439522 WIPF1 -0.36 -4.66 -0.39 8.01e-6 Urate levels (BMI interaction); TGCT cis rs9549367 0.569 rs3024738 chr13:113819921 T/A cg18105134 chr13:113819100 PROZ 0.47 8.13 0.59 3.68e-13 Platelet distribution width; TGCT cis rs17253792 0.822 rs112238223 chr14:56056144 C/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs7078160 0.766 rs61872990 chr10:118649443 T/C cg10595547 chr10:119310911 NA -0.57 -4.45 -0.37 1.87e-5 Nonsyndromic cleft lip with or without cleft palate;Orofacial clefts; TGCT cis rs7940866 0.740 rs2162060 chr11:130830763 A/G cg05962950 chr11:130786565 SNX19 0.66 6.19 0.49 7.96e-9 Schizophrenia; TGCT cis rs9638182 1.000 rs1051921 chr7:73007943 G/A cg14087351 chr7:73037990 MLXIPL -0.55 -4.6 -0.38 1.01e-5 Triglycerides; TGCT cis rs754133 0.964 rs894737 chr12:54418143 A/C cg16264616 chr12:54390824 NA 0.34 5.19 0.42 8.23e-7 Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist circumference adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for body mass index; TGCT cis rs12458462 0.892 rs35928863 chr18:77438956 A/G cg11879182 chr18:77439856 CTDP1 0.67 7.67 0.57 4.44e-12 Monocyte count; TGCT trans rs2469997 0.925 rs2470018 chr8:120361655 C/T cg01792902 chr3:178864926 PIK3CA 0.83 6.77 0.52 4.49e-10 Hypertension (SNP x SNP interaction); TGCT trans rs561341 0.769 rs9899093 chr17:30191954 C/G cg20587970 chr11:113659929 NA -0.85 -8.52 -0.61 4.49e-14 Hip circumference adjusted for BMI; TGCT cis rs12188164 0.965 rs77101200 chr5:443059 G/T cg26850624 chr5:429559 AHRR -0.2 -4.86 -0.4 3.48e-6 Cystic fibrosis severity; TGCT cis rs9868809 0.772 rs9809222 chr3:48714411 C/T cg00383909 chr3:49044727 WDR6 0.88 5.29 0.43 5.32e-7 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs3733585 0.674 rs7375643 chr4:9955239 A/G cg00071950 chr4:10020882 SLC2A9 -0.65 -8.23 -0.59 2.24e-13 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs8180040 1.000 rs295461 chr3:47368010 T/C cg27129171 chr3:47204927 SETD2 0.7 8.88 0.62 6.43e-15 Colorectal cancer; TGCT cis rs892961 0.932 rs7223768 chr17:75410521 G/A cg05865280 chr17:75406074 SEPT9 0.29 6.99 0.53 1.46e-10 Airflow obstruction; TGCT cis rs3806843 0.576 rs246027 chr5:140333601 A/G cg01369220 chr5:140248564 PCDHA7;PCDHA6;PCDHA11;PCDHA10;PCDHA4;PCDHA8;PCDHA1;PCDHA2;PCDHA9;PCDHA5;PCDHA3 -0.41 -5.24 -0.43 6.79e-7 Depressive symptoms (multi-trait analysis); TGCT cis rs7959452 0.901 rs1384 chr12:69747834 C/T cg14784868 chr12:69753453 YEATS4 0.7 7.22 0.54 4.55e-11 Blood protein levels; TGCT cis rs10504229 0.871 rs56372514 chr8:58157166 A/G cg24829409 chr8:58192753 C8orf71 -0.55 -5.06 -0.41 1.46e-6 Developmental language disorder (linguistic errors); TGCT cis rs9902453 0.808 rs78154346 chr17:28169493 C/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs7010267 0.570 rs2326194 chr8:120043960 C/T cg17171407 chr8:119960777 TNFRSF11B 0.26 4.59 0.38 1.06e-5 Total body bone mineral density (age 45-60); TGCT cis rs4713118 0.527 rs9461433 chr6:28095172 C/T cg12963246 chr6:28129442 ZNF389 0.52 5.01 0.41 1.85e-6 Parkinson's disease; TGCT cis rs9653442 0.527 rs2164712 chr2:100745404 C/G cg07810366 chr2:100720526 AFF3 -0.38 -5.28 -0.43 5.55e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs655029 0.848 rs10176736 chr2:31465541 G/T cg14018959 chr2:31480232 EHD3 -0.32 -4.43 -0.37 2.01e-5 Mean platelet volume;Platelet distribution width;Platelet count;Plateletcrit; TGCT cis rs7100689 0.784 rs7082102 chr10:82104890 A/C cg01528321 chr10:82214614 TSPAN14 0.8 8.0 0.58 7.5e-13 Post bronchodilator FEV1; TGCT cis rs7833790 0.700 rs7834483 chr8:82704828 A/G cg27398817 chr8:82754497 SNX16 -0.64 -4.98 -0.41 2.05e-6 Diastolic blood pressure; TGCT cis rs2594989 0.779 rs2596815 chr3:11594930 A/G cg00170343 chr3:11313890 ATG7 -0.69 -5.22 -0.42 7.38e-7 Circulating chemerin levels; TGCT cis rs2836974 0.932 rs6517526 chr21:40581530 T/C cg17971929 chr21:40555470 PSMG1 0.98 9.41 0.65 3.31e-16 Cognitive function; TGCT cis rs9926296 0.548 rs12447465 chr16:89829895 C/T cg26513180 chr16:89883248 FANCA 1.04 14.52 0.79 1.58e-28 Vitiligo; TGCT cis rs13108904 0.967 rs900028 chr4:1279162 A/T cg13395646 chr4:1353034 KIAA1530 -0.39 -4.97 -0.41 2.2e-6 Obesity-related traits; TGCT cis rs12765878 0.812 rs2984132 chr10:105657892 T/C cg11005552 chr10:105648138 OBFC1 -0.44 -7.29 -0.55 3.12e-11 Coronary artery disease; TGCT cis rs28595532 0.841 rs115233595 chr4:119744214 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6582630 0.638 rs12425379 chr12:38523705 G/A cg26384229 chr12:38710491 ALG10B -0.53 -4.78 -0.39 4.9100000000000004e-06 Drug-induced liver injury (flucloxacillin); TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs7917772 0.503 rs7902306 chr10:104290462 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.71 6.65 0.51 8.56e-10 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6746896 0.959 rs58361269 chr2:97403110 G/A cg26085987 chr2:97230376 NA 0.19 4.69 0.39 7.03e-6 Bipolar disorder; TGCT cis rs7937682 0.562 rs630002 chr11:111377758 G/A cg09085632 chr11:111637200 PPP2R1B -0.68 -6.36 -0.5 3.55e-9 Primary sclerosing cholangitis; TGCT trans rs7618501 0.633 rs4688690 chr3:50022292 G/A cg21659725 chr3:3221576 CRBN 0.76 9.02 0.63 2.92e-15 Intelligence (multi-trait analysis); TGCT cis rs2541522 0.600 rs8057467 chr16:10744950 G/A cg21839338 chr16:10912331 FAM18A 0.4 4.48 0.37 1.65e-5 Gut microbiome composition (summer); TGCT cis rs7216064 1.000 rs12451721 chr17:65939075 G/A cg12091567 chr17:66097778 LOC651250 -0.82 -6.11 -0.48 1.17e-8 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs2688608 0.933 rs2688614 chr10:75652876 G/A cg02947784 chr10:75434997 AGAP5 0.17 4.61 0.38 9.79e-6 Inflammatory bowel disease; TGCT cis rs9611519 0.602 rs8138520 chr22:41412928 A/G cg03806693 chr22:41940476 POLR3H -0.64 -6.09 -0.48 1.29e-8 Neuroticism; TGCT cis rs7954584 0.583 rs6486782 chr12:122359172 T/C cg21171335 chr12:122356390 WDR66 0.59 6.19 0.49 8.15e-9 Mean corpuscular volume; TGCT cis rs7805747 1.000 rs56012466 chr7:151406788 G/A cg17611936 chr7:151411526 PRKAG2 0.51 6.51 0.5 1.69e-9 Glomerular filtration rate in non diabetics (creatinine);Chronic kidney disease;Glomerular filtration rate (creatinine); TGCT cis rs736408 0.609 rs2336545 chr3:52787603 C/T cg11041457 chr3:52719354 GNL3;PBRM1 -0.58 -5.74 -0.46 6.96e-8 Bipolar disorder; TGCT cis rs6540559 0.673 rs11805830 chr1:209984969 C/T cg22029157 chr1:209979665 IRF6 0.74 5.53 0.44 1.84e-7 Cleft lip with or without cleft palate; TGCT trans rs1814175 0.817 rs28544182 chr11:50049577 G/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs9467773 0.935 rs11752946 chr6:26560364 C/A cg05738196 chr6:26577821 NA 0.89 12.06 0.73 1.22e-22 Intelligence (multi-trait analysis); TGCT cis rs6860806 0.661 rs6890009 chr5:131580033 G/T cg24060327 chr5:131705240 SLC22A5 -0.54 -5.36 -0.43 3.97e-7 Breast cancer; TGCT cis rs9868809 0.505 rs9877685 chr3:48748588 C/T cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs7119 0.604 rs939488 chr15:77867780 T/C cg27398640 chr15:77910606 LINGO1 0.27 4.87 0.4 3.31e-6 Type 2 diabetes; TGCT cis rs6570726 0.935 rs384453 chr6:145815145 G/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs908922 0.924 rs6669608 chr1:152475233 A/G cg20991723 chr1:152506922 NA 0.46 5.74 0.46 6.84e-8 Hair morphology; TGCT cis rs7312933 0.703 rs11181380 chr12:42616040 A/T cg19980929 chr12:42632907 YAF2 0.46 6.1 0.48 1.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs2710642 0.861 rs2710644 chr2:63248968 A/C cg17519650 chr2:63277830 OTX1 0.62 5.42 0.44 3.05e-7 LDL cholesterol levels;LDL cholesterol; TGCT cis rs916888 0.610 rs199536 chr17:44820425 T/C cg01570182 chr17:44337453 NA -0.78 -7.51 -0.56 1.01e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7614311 0.594 rs1046025 chr3:63996262 C/T cg22134162 chr3:63841271 THOC7 -0.34 -4.7 -0.39 6.92e-6 Lung function (FVC);Lung function (FEV1); TGCT cis rs6582630 0.531 rs3850000 chr12:38483752 T/C cg13010199 chr12:38710504 ALG10B 0.58 4.72 0.39 6.16e-6 Drug-induced liver injury (flucloxacillin); TGCT trans rs17685 0.632 rs1859793 chr7:75821283 G/A cg19862616 chr7:65841803 NCRNA00174 0.51 8.99 0.63 3.42e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs10504229 0.593 rs17192845 chr8:58053339 C/T cg08219700 chr8:58056026 NA 0.4 4.84 0.4 3.81e-6 Developmental language disorder (linguistic errors); TGCT cis rs1205863 0.541 rs1205845 chr6:11929449 C/A cg07106625 chr6:11870215 NA 0.46 4.76 0.39 5.38e-6 Disc degeneration (lumbar); TGCT cis rs709400 0.663 rs62007684 chr14:103894223 T/C cg26031613 chr14:104095156 KLC1 0.88 9.68 0.66 7.7e-17 Body mass index; TGCT cis rs713587 0.967 rs10182181 chr2:25150296 C/T cg01884057 chr2:25150051 NA -0.41 -8.56 -0.61 3.57e-14 Body mass index in non-asthmatics; TGCT cis rs6570726 0.791 rs401561 chr6:145835917 G/T cg05347473 chr6:146136440 FBXO30 0.53 4.95 0.41 2.4e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9325144 0.624 rs10783330 chr12:39114084 A/G cg13010199 chr12:38710504 ALG10B -0.52 -4.58 -0.38 1.13e-5 Morning vs. evening chronotype; TGCT cis rs6840360 0.582 rs4473638 chr4:152322146 C/T cg17479576 chr4:152424074 FAM160A1 -0.63 -6.8 -0.52 3.99e-10 Intelligence (multi-trait analysis); TGCT cis rs9926296 0.682 rs645019 chr16:89716883 C/T cg26513180 chr16:89883248 FANCA -0.68 -6.4 -0.5 2.86e-9 Vitiligo; TGCT cis rs739496 0.579 rs6489810 chr12:112277406 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Platelet count; TGCT cis rs9926296 0.548 rs12447465 chr16:89829895 C/T cg21285383 chr16:89894308 SPIRE2 0.44 6.9 0.53 2.42e-10 Vitiligo; TGCT cis rs1580019 0.563 rs34201720 chr7:32568935 G/A cg06627557 chr7:32535165 LSM5;AVL9 1.14 15.01 0.8 1.13e-29 Cognitive ability; TGCT cis rs7677751 0.806 rs4864847 chr4:55071953 G/A cg17187183 chr4:55093834 PDGFRA 0.47 6.0 0.47 2.01e-8 Corneal astigmatism; TGCT cis rs9814567 0.806 rs1880375 chr3:134322163 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.76 -7.11 -0.54 8.15e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT trans rs804280 0.509 rs13276433 chr8:11783036 A/G cg15556689 chr8:8085844 FLJ10661 0.8 7.56 0.56 7.7e-12 Myopia (pathological); TGCT cis rs6840360 0.642 rs2709820 chr4:152384039 A/G cg17479576 chr4:152424074 FAM160A1 -0.6 -6.34 -0.49 3.98e-9 Intelligence (multi-trait analysis); TGCT cis rs7647973 0.626 rs62262672 chr3:49655927 T/A cg05785598 chr3:49045655 WDR6 -0.43 -5.13 -0.42 1.07e-6 Menarche (age at onset); TGCT cis rs7398996 1 rs7398996 chr12:53659448 C/T cg16917193 chr12:54089295 NA 0.68 5.16 0.42 9.53e-7 Total body bone mineral density (age 45-60); TGCT cis rs79349575 0.783 rs12602933 chr17:47029280 G/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs16957091 0.647 rs28564939 chr15:43376592 T/C cg17935677 chr15:44119062 WDR76 0.54 4.83 0.4 3.88e-6 MGMT methylation in smokers; TGCT cis rs7666738 0.830 rs28515641 chr4:98726419 G/A cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs3733585 0.673 rs6850143 chr4:9958924 T/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.67 -0.51 7.44e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs12510870 0.564 rs12640883 chr4:74408840 A/G cg05868023 chr4:75230803 EREG 0.54 4.75 0.39 5.46e-6 Iris color (b* coordinate); TGCT cis rs10114408 0.918 rs10992963 chr9:96657624 G/A cg13679303 chr9:96623674 NA -0.36 -4.73 -0.39 5.91e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs7811142 1.000 rs11766752 chr7:100073292 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs904251 0.861 rs1757169 chr6:37487076 G/T cg01843034 chr6:37503916 NA -0.52 -6.29 -0.49 4.88e-9 Cognitive performance; TGCT cis rs6088590 0.687 rs6088582 chr20:33286798 G/A cg06115741 chr20:33292138 TP53INP2 0.57 4.86 0.4 3.51e-6 Coronary artery disease; TGCT cis rs1467026 0.523 rs9865548 chr3:12801785 C/T cg05775895 chr3:12838266 CAND2 0.7 7.16 0.54 6.26e-11 P wave duration; TGCT cis rs11190604 1.000 rs7088827 chr10:102303865 C/G cg23241863 chr10:102295624 HIF1AN 0.7 5.14 0.42 1.02e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9858542 0.537 rs9874474 chr3:49326178 A/G cg00383909 chr3:49044727 WDR6 0.69 4.78 0.39 4.84e-6 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs36051895 0.664 rs3780381 chr9:5114523 A/C cg02405213 chr9:5042618 JAK2 -0.69 -9.14 -0.63 1.54e-15 Pediatric autoimmune diseases; TGCT cis rs11190604 1.000 rs17746014 chr10:102315354 T/C cg23241863 chr10:102295624 HIF1AN 0.68 5.18 0.42 8.89e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs11585357 0.793 rs11588418 chr1:17616445 A/G cg08277548 chr1:17600880 PADI3 -0.96 -9.72 -0.66 5.97e-17 Hair shape; TGCT cis rs7772486 0.754 rs4896838 chr6:146015451 T/C cg05347473 chr6:146136440 FBXO30 -0.51 -4.8 -0.4 4.44e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7809950 0.678 rs62482499 chr7:106975059 C/G cg23024343 chr7:107201750 COG5 -0.44 -6.03 -0.48 1.75e-8 Coronary artery disease; TGCT cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg21724239 chr8:58056113 NA 0.49 5.23 0.43 6.92e-7 Developmental language disorder (linguistic errors); TGCT cis rs2997447 0.802 rs72884792 chr1:26436688 G/C cg03844060 chr1:26490628 NA 0.28 4.55 0.38 1.27e-5 QRS complex (12-leadsum); TGCT cis rs7192750 0.586 rs4788570 chr16:71920144 G/A cg06353428 chr16:71660113 MARVELD3 0.82 7.26 0.55 3.82e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs3617 0.573 rs56383738 chr3:52908398 T/C cg05573699 chr3:52720067 GNL3;PBRM1 0.5 4.9 0.4 2.9e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs13242816 1.000 rs13226307 chr7:116137485 A/T cg16553024 chr7:116138462 CAV2 0.44 5.31 0.43 4.81e-7 P wave duration; TGCT cis rs17270561 0.666 rs4712976 chr6:25842203 C/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.58 4.47 0.37 1.78e-5 Iron status biomarkers; TGCT cis rs743757 1.000 rs734767 chr3:50431410 C/G cg04614380 chr3:50192449 SEMA3F 0.67 4.62 0.38 9.47e-6 Diastolic blood pressure; TGCT cis rs2797160 0.651 rs1268093 chr6:126029235 C/T cg05901451 chr6:126070800 HEY2 0.76 6.81 0.52 3.83e-10 Endometrial cancer; TGCT cis rs67311347 0.956 rs9822870 chr3:40514890 A/C cg17264618 chr3:40429014 ENTPD3 -0.33 -4.85 -0.4 3.66e-6 Renal cell carcinoma; TGCT cis rs1799949 0.965 rs12947782 chr17:41279882 A/G cg19454999 chr17:41278357 BRCA1;NBR2 0.5 5.23 0.43 6.92e-7 Menopause (age at onset); TGCT cis rs9913156 0.789 rs56003988 chr17:4600764 G/A cg19197139 chr17:4613644 ARRB2 0.83 7.74 0.57 3.03e-12 Lymphocyte counts; TGCT cis rs35306767 0.714 rs11250228 chr10:1074887 A/G cg26597838 chr10:835615 NA 0.51 5.94 0.47 2.71e-8 Eosinophil percentage of granulocytes; TGCT cis rs35306767 0.715 rs1250891 chr10:1040159 G/C cg18964960 chr10:1102726 WDR37 0.76 5.32 0.43 4.76e-7 Eosinophil percentage of granulocytes; TGCT cis rs4820539 1.000 rs916583 chr22:23469267 C/T cg14186256 chr22:23484241 RTDR1 0.98 12.28 0.74 3.5e-23 Bone mineral density; TGCT cis rs2836974 0.583 rs9636957 chr21:40705847 G/A cg11890956 chr21:40555474 PSMG1 -0.72 -6.47 -0.5 2.07e-9 Cognitive function; TGCT cis rs62244186 0.659 rs9835270 chr3:44553722 G/A cg02073558 chr3:44770973 ZNF501 0.61 5.81 0.46 4.92e-8 Depressive symptoms; TGCT cis rs637571 0.584 rs594689 chr11:65635559 G/A cg26695010 chr11:65641043 EFEMP2 0.58 5.89 0.47 3.4e-8 Eosinophil percentage of white cells; TGCT cis rs6558174 0.965 rs7831119 chr8:22489678 C/T cg03733263 chr8:22462867 KIAA1967 -0.65 -5.27 -0.43 5.95e-7 Breast cancer; TGCT trans rs1814175 0.817 rs7483795 chr11:49704930 G/A cg11707556 chr5:10655725 ANKRD33B -0.38 -7.6 -0.56 6.14e-12 Height; TGCT cis rs823143 0.570 rs1361754 chr1:205801872 C/T cg14893161 chr1:205819251 PM20D1 -0.53 -7.48 -0.56 1.18e-11 Monocyte percentage of white cells; TGCT cis rs1997103 0.765 rs55686950 chr7:55396552 A/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9291683 0.527 rs3822247 chr4:10094671 G/A cg11266682 chr4:10021025 SLC2A9 -0.58 -6.64 -0.51 8.94e-10 Bone mineral density; TGCT cis rs9682041 0.696 rs13101192 chr3:170080752 C/G cg07589077 chr3:170072950 NA 0.28 4.73 0.39 6.1e-6 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs9640161 0.830 rs36069544 chr7:150061538 G/A cg10018233 chr7:150070692 REPIN1 0.33 4.94 0.41 2.46e-6 Blood protein levels;Circulating chemerin levels; TGCT cis rs13188771 0.651 rs59109546 chr5:100879961 G/A cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs4689388 0.609 rs1046319 chr4:6304286 C/T cg25554036 chr4:6271136 WFS1 0.55 6.45 0.5 2.31e-9 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9430161 0.611 rs35033941 chr1:11034382 C/T cg02454025 chr1:11042201 C1orf127 0.94 11.31 0.71 8.14e-21 Ewing sarcoma; TGCT cis rs6750047 0.747 rs2116229 chr2:38270490 G/T cg07380506 chr2:38303506 CYP1B1 0.57 5.04 0.41 1.63e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs17681684 0.521 rs12150554 chr17:9753370 T/C cg15743799 chr17:9805578 RCVRN -0.26 -5.53 -0.44 1.79e-7 GIP levels in response to oral glucose tolerance test (fasting); TGCT cis rs1371867 0.846 rs1660353 chr8:101250907 C/T cg06002616 chr8:101225028 SPAG1 0.52 6.2 0.49 7.79e-9 Atrioventricular conduction; TGCT cis rs3096299 0.566 rs4129126 chr16:89561475 A/C cg06640241 chr16:89574553 SPG7 0.54 4.71 0.39 6.47e-6 Multiple myeloma (IgH translocation); TGCT cis rs11718455 0.585 rs1491708 chr3:43911578 C/T cg08738300 chr3:44038990 NA 0.66 4.52 0.38 1.44e-5 Coronary artery disease; TGCT cis rs904251 0.737 rs914347 chr6:37484970 A/C cg25019722 chr6:37503610 NA -0.48 -6.63 -0.51 9.21e-10 Cognitive performance; TGCT cis rs79057730 0.599 rs4720893 chr7:804434 G/A cg06242242 chr7:766104 PRKAR1B;HEATR2 0.65 5.41 0.44 3.16e-7 Initial pursuit acceleration; TGCT cis rs10504229 0.683 rs2291765 chr8:58142874 C/T cg08280861 chr8:58055591 NA 0.35 4.66 0.39 8.04e-6 Developmental language disorder (linguistic errors); TGCT cis rs2456568 0.900 rs2511376 chr11:93670388 C/T cg26875233 chr11:93583750 C11orf90 -0.45 -5.6 -0.45 1.31e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs1059312 0.545 rs7312683 chr12:129280105 T/C cg09035930 chr12:129282057 SLC15A4 0.51 7.5 0.56 1.09e-11 Systemic lupus erythematosus; TGCT cis rs7226408 0.894 rs72883597 chr18:34393197 T/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs76935404 0.811 rs4609955 chr19:41433613 T/C cg19493303 chr19:41414353 NA 0.41 5.07 0.41 1.4e-6 nicotine metabolite ratio in current smokers; TGCT cis rs10411936 1.000 rs1870071 chr19:16505106 A/G cg19006008 chr19:16999768 F2RL3 -0.27 -4.97 -0.41 2.21e-6 White blood cell count;Multiple sclerosis; TGCT cis rs904251 0.580 rs62408367 chr6:37444813 G/A cg25019722 chr6:37503610 NA -0.47 -6.66 -0.51 7.94e-10 Cognitive performance; TGCT cis rs10504229 0.728 rs72650856 chr8:58152695 C/T cg11062466 chr8:58055876 NA 0.38 4.62 0.38 9.5e-6 Developmental language disorder (linguistic errors); TGCT cis rs9787249 0.915 rs6664570 chr1:40206298 G/A cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT cis rs7959452 0.640 rs4761233 chr12:69722880 T/C cg20891283 chr12:69753455 YEATS4 0.67 6.67 0.51 7.56e-10 Blood protein levels; TGCT trans rs6089829 0.888 rs4809468 chr20:61673566 T/C cg17470723 chr8:74884337 TCEB1 0.78 6.87 0.53 2.7e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs10089 0.953 rs72794400 chr5:127516028 C/G cg19767477 chr5:127420684 SLC12A2 -0.45 -4.65 -0.39 8.47e-6 Ileal carcinoids; TGCT cis rs8017423 1.000 rs2184281 chr14:90685923 A/G cg04374321 chr14:90722782 PSMC1 -0.76 -7.73 -0.57 3.19e-12 Mortality in heart failure; TGCT cis rs4900538 0.963 rs1190553 chr14:102915331 G/T cg18135206 chr14:102964638 TECPR2 -0.22 -5.31 -0.43 4.81e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs2832191 0.967 rs2832216 chr21:30521921 C/T cg08807101 chr21:30365312 RNF160 0.52 4.97 0.41 2.21e-6 Dental caries; TGCT cis rs12777 0.571 rs7720592 chr5:131844744 G/T cg16609957 chr5:132161867 SHROOM1 -0.34 -4.6 -0.38 1.04e-5 Fibrinogen levels; TGCT cis rs67311347 1.000 rs11707278 chr3:40487075 A/T cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs1008375 1.000 rs28501187 chr4:17643620 G/A cg10189774 chr4:17578691 LAP3 0.56 5.04 0.41 1.57e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9883204 0.807 rs72964564 chr3:123054770 A/C cg04890266 chr3:123102914 ADCY5 0.34 4.65 0.39 8.51e-6 Birth weight; TGCT cis rs2070488 0.775 rs762318 chr3:38516369 C/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.64 0.57 5.12e-12 Electrocardiographic conduction measures; TGCT cis rs60154123 0.772 rs845452 chr1:210417861 C/T cg22029157 chr1:209979665 IRF6 0.63 4.52 0.38 1.45e-5 Coronary artery disease; TGCT cis rs3087591 0.683 rs2525567 chr17:29675673 C/A cg24425628 chr17:29625626 OMG;NF1 0.39 5.52 0.44 1.87e-7 Hip circumference; TGCT cis rs10504229 0.954 rs114134184 chr8:58181969 G/A cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs9296092 0.538 rs56205713 chr6:33517510 A/G cg13560919 chr6:33536144 NA -0.21 -4.74 -0.39 5.72e-6 Age at smoking initiation in chronic obstructive pulmonary disease; TGCT cis rs707040 0.921 rs12617950 chr2:155234278 G/T cg18104148 chr2:154337490 NA 0.19 4.63 0.38 9.05e-6 Sudden cardiac arrest; TGCT cis rs8013055 0.846 rs7160747 chr14:105983740 A/G cg19700328 chr14:106028568 NA -0.48 -5.12 -0.42 1.14e-6 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs3733585 0.699 rs6449157 chr4:9960442 G/A cg11266682 chr4:10021025 SLC2A9 -0.57 -7.47 -0.56 1.23e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs875971 0.895 rs6460300 chr7:65952924 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs58950470 0.887 rs1787034 chr11:65382564 A/G cg27068330 chr11:65405492 SIPA1 0.54 4.71 0.39 6.47e-6 Schizophrenia; TGCT cis rs2836950 0.565 rs8130320 chr21:40580258 C/T cg06238570 chr21:40685208 BRWD1 -0.59 -6.14 -0.48 1.05e-8 Menarche (age at onset); TGCT cis rs3087591 0.659 rs2525570 chr17:29681245 A/G cg24425628 chr17:29625626 OMG;NF1 0.39 5.59 0.45 1.36e-7 Hip circumference; TGCT cis rs7100689 0.784 rs7078075 chr10:82162768 A/G cg01528321 chr10:82214614 TSPAN14 0.87 8.71 0.62 1.62e-14 Post bronchodilator FEV1; TGCT cis rs10504229 0.815 rs16921955 chr8:58164553 C/T cg22535103 chr8:58192502 C8orf71 -0.38 -4.44 -0.37 1.93e-5 Developmental language disorder (linguistic errors); TGCT cis rs8020441 0.945 rs4259956 chr14:51170177 T/G cg04730355 chr14:51134070 SAV1 0.73 5.75 0.46 6.67e-8 Cognitive performance; TGCT cis rs7618915 0.547 rs7642198 chr3:52677960 T/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs10746514 1.000 rs11122416 chr1:232249928 A/G cg09506761 chr1:232265262 NA 0.49 4.98 0.41 2.04e-6 Response to statin therapy; TGCT cis rs7811142 0.830 rs77861211 chr7:99962096 T/C cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs4304924 0.500 rs9601109 chr13:79220114 A/G cg05295671 chr13:79234353 RNF219 0.78 6.17 0.48 8.8e-9 Large artery stroke; TGCT cis rs9291683 0.588 rs34501273 chr4:9996996 C/T cg11266682 chr4:10021025 SLC2A9 0.7 9.33 0.64 5.22e-16 Bone mineral density; TGCT cis rs763121 0.853 rs138704 chr22:39133410 A/G cg06022373 chr22:39101656 GTPBP1 0.74 7.15 0.54 6.67e-11 Menopause (age at onset); TGCT cis rs7811142 0.830 rs75636500 chr7:99947657 C/G cg00814883 chr7:100076585 TSC22D4 -0.85 -8.62 -0.61 2.62e-14 Platelet count; TGCT cis rs10782582 0.593 rs11579752 chr1:76178694 C/T cg10523679 chr1:76189770 ACADM -0.64 -6.67 -0.51 7.67e-10 Daytime sleep phenotypes; TGCT cis rs12368653 0.582 rs2307095 chr12:58026001 G/A cg12615879 chr12:58013172 SLC26A10 0.59 7.1 0.54 8.71e-11 Multiple sclerosis; TGCT cis rs524281 0.861 rs10791856 chr11:65964650 T/C cg00563793 chr11:65837595 PACS1 0.54 4.71 0.39 6.4e-6 Electroencephalogram traits; TGCT cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg03264133 chr6:25882463 NA -0.59 -5.37 -0.43 3.68e-7 Intelligence (multi-trait analysis); TGCT cis rs12142240 0.698 rs3991877 chr1:46853749 C/A cg00530320 chr1:46809349 NSUN4 0.29 5.79 0.46 5.34e-8 Menopause (age at onset); TGCT cis rs11690935 0.632 rs9789538 chr2:172618474 G/C cg13550731 chr2:172543902 DYNC1I2 0.67 5.87 0.47 3.79e-8 Schizophrenia; TGCT cis rs228437 0.565 rs7765188 chr6:134961316 T/C cg09872934 chr6:134495829 SGK1 -0.56 -4.76 -0.39 5.38e-6 Melanoma; TGCT cis rs11264213 0.515 rs9660657 chr1:36548941 C/T cg27506609 chr1:36549197 TEKT2 -0.4 -6.54 -0.51 1.48e-9 Schizophrenia; TGCT cis rs6964587 0.935 rs28412174 chr7:91577245 T/G cg22709100 chr7:91322751 NA -0.27 -4.48 -0.37 1.68e-5 Breast cancer; TGCT trans rs324780 0.544 rs3110193 chr12:83906425 G/A cg27144766 chr5:150604977 CCDC69 0.24 6.63 0.51 9.42e-10 Vertical cup-disc ratio; TGCT cis rs3617 0.573 rs3821873 chr3:52913006 C/T cg11645453 chr3:52864694 ITIH4 -0.28 -5.32 -0.43 4.65e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs12477438 0.798 rs896886 chr2:99652713 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 0.83 8.44 0.6 7.12e-14 Chronic sinus infection; TGCT cis rs4924935 0.509 rs8074020 chr17:18801380 T/C cg26378065 chr17:18585709 ZNF286B 0.51 4.59 0.38 1.09e-5 Pancreatic cancer; TGCT cis rs7209700 0.821 rs4642 chr17:45369777 A/G cg21624342 chr17:45890973 OSBPL7 0.19 5.09 0.42 1.32e-6 IgG glycosylation; TGCT trans rs208515 0.525 rs12191500 chr6:66668681 A/G cg15611600 chr13:45563400 KIAA1704;NUFIP1 0.9 9.56 0.65 1.46e-16 Exhaled nitric oxide levels; TGCT cis rs4378999 0.660 rs9869945 chr3:50849368 A/G ch.3.1075622R chr3:50010873 RBM6 -0.37 -4.55 -0.38 1.27e-5 Waist circumference adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction); TGCT cis rs2067615 0.524 rs7959062 chr12:107107334 G/T cg15890332 chr12:107067104 RFX4 0.29 5.77 0.46 5.9e-8 Heart rate; TGCT cis rs6921919 0.583 rs4357130 chr6:28367683 T/G cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.27 -0.43 5.78e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2535633 0.631 rs2581819 chr3:53016552 C/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.49 -4.48 -0.37 1.66e-5 Body mass index; TGCT cis rs9611565 0.802 rs9611577 chr22:41793090 T/G cg13695892 chr22:41940480 POLR3H -0.77 -7.47 -0.56 1.24e-11 Vitiligo; TGCT cis rs7582180 0.614 rs10193204 chr2:101004540 A/G cg14675211 chr2:100938903 LONRF2 -0.5 -4.8 -0.4 4.51e-6 Intelligence (multi-trait analysis); TGCT cis rs7523273 0.925 rs4844394 chr1:208000625 C/T cg22525895 chr1:207977042 MIR29B2 -0.48 -8.57 -0.61 3.42e-14 Schizophrenia; TGCT cis rs1691799 0.867 rs1168348 chr12:66757168 G/A cg16791601 chr12:66731901 HELB -0.29 -6.18 -0.49 8.39e-9 White blood cell count (basophil); TGCT cis rs909674 0.515 rs9611170 chr22:39784845 G/C cg05872129 chr22:39784769 NA -1.02 -11.79 -0.73 5.43e-22 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs453301 0.624 rs4841083 chr8:8870428 A/G cg06636001 chr8:8085503 FLJ10661 0.77 6.54 0.51 1.43e-9 Joint mobility (Beighton score); TGCT cis rs1005277 0.579 rs2749616 chr10:38510993 A/T cg25427524 chr10:38739819 LOC399744 -0.4 -8.32 -0.6 1.33e-13 Extrinsic epigenetic age acceleration; TGCT cis rs5760092 0.842 rs5760103 chr22:24248781 A/G cg18538332 chr22:24372958 LOC391322 -0.76 -6.14 -0.48 1.05e-8 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs61935443 0.562 rs11107791 chr12:95316374 G/A cg21533806 chr12:95267307 NA 0.55 4.59 0.38 1.08e-5 Schizophrenia; TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg01802117 chr1:53393560 SCP2 -0.44 -5.39 -0.44 3.39e-7 Monocyte count; TGCT cis rs8077889 0.871 rs8065043 chr17:41900984 G/A cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs922182 0.613 rs894660 chr15:64234334 T/C cg02919090 chr15:64263738 DAPK2 -0.33 -6.14 -0.48 1.05e-8 Blood protein levels; TGCT cis rs2839186 0.771 rs2839155 chr21:47639992 A/G cg13732083 chr21:47605072 C21orf56 0.37 4.69 0.39 7.07e-6 Testicular germ cell tumor; TGCT cis rs7666738 0.753 rs7698541 chr4:98986351 T/A cg17366294 chr4:99064904 C4orf37 0.69 7.01 0.53 1.38e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs561341 0.681 rs56064462 chr17:30235116 G/A cg13647721 chr17:30228624 UTP6 0.62 4.71 0.39 6.43e-6 Hip circumference adjusted for BMI; TGCT cis rs2243480 1.000 rs1404147 chr7:65264524 C/T cg20637647 chr7:64974828 NA 0.7 4.62 0.38 9.47e-6 Diabetic kidney disease; TGCT cis rs2439831 1.000 rs690316 chr15:43737880 C/A cg27015174 chr15:43622946 ADAL;LCMT2 0.81 5.73 0.46 7.15e-8 Lung cancer in ever smokers; TGCT cis rs1018836 0.608 rs10111060 chr8:91491152 T/C cg16814680 chr8:91681699 NA -0.68 -6.83 -0.52 3.31e-10 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs3806843 1.000 rs1030165 chr5:140185448 G/A cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs903263 0.965 rs7532712 chr1:84594117 G/C cg09664975 chr1:84543551 PRKACB 0.5 4.74 0.39 5.69e-6 Breast cancer (male); TGCT cis rs6725041 0.819 rs1996763 chr2:213082269 T/C cg16329650 chr2:213403929 ERBB4 -0.54 -4.61 -0.38 9.88e-6 QT interval (ambient particulate matter interaction); TGCT cis rs9611565 0.765 rs132921 chr22:41812044 G/A cg17554472 chr22:41940697 POLR3H 0.42 4.64 0.38 8.64e-6 Vitiligo; TGCT cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg06601766 chr17:61851465 DDX42;CCDC47 0.53 4.45 0.37 1.91e-5 Height; TGCT cis rs938554 0.558 rs4697701 chr4:9946095 C/T cg00071950 chr4:10020882 SLC2A9 -0.5 -5.0 -0.41 1.88e-6 Blood metabolite levels; TGCT cis rs908922 0.676 rs4240884 chr1:152529792 C/T cg20991723 chr1:152506922 NA -0.46 -6.16 -0.48 9.18e-9 Hair morphology; TGCT cis rs72781680 0.848 rs56371415 chr2:23932603 C/G cg08917208 chr2:24149416 ATAD2B 0.89 5.41 0.44 3.11e-7 Lymphocyte counts; TGCT cis rs709400 0.633 rs8013101 chr14:103951772 G/C cg12935359 chr14:103987150 CKB -0.36 -5.64 -0.45 1.11e-7 Body mass index; TGCT cis rs28595532 0.920 rs17324884 chr4:119771477 C/T cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs6121246 0.697 rs6120970 chr20:30232452 C/T cg21427119 chr20:30132790 HM13 -0.37 -5.19 -0.42 8.51e-7 Mean corpuscular hemoglobin; TGCT cis rs951366 0.646 rs1772159 chr1:205759195 G/A cg14893161 chr1:205819251 PM20D1 0.65 10.12 0.67 6.64e-18 Menarche (age at onset); TGCT cis rs7811142 0.720 rs112622797 chr7:99917416 G/A cg00814883 chr7:100076585 TSC22D4 -0.86 -8.48 -0.61 5.77e-14 Platelet count; TGCT cis rs2230307 0.536 rs564938 chr1:100592901 T/C cg24955406 chr1:100503596 HIAT1 -0.77 -5.23 -0.43 6.91e-7 Carotid intima media thickness; TGCT cis rs3741151 1.000 rs112628073 chr11:73013626 C/T cg17517138 chr11:73019481 ARHGEF17 1.16 5.54 0.45 1.7e-7 GIP levels in response to oral glucose tolerance test (120 minutes); TGCT cis rs9650657 0.615 rs1549796 chr8:10692359 C/T cg16664915 chr8:10907788 XKR6 -0.29 -4.58 -0.38 1.1e-5 Neuroticism; TGCT cis rs2159324 1.000 rs10421129 chr19:45695836 G/A cg24080119 chr19:45644694 NA 0.3 4.81 0.4 4.31e-6 Quantitative traits; TGCT cis rs6674176 0.628 rs12145999 chr1:44428632 C/T cg12908607 chr1:44402522 ARTN -0.68 -8.19 -0.59 2.7e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs2839186 0.647 rs9976233 chr21:47616913 G/A cg13012494 chr21:47604986 C21orf56 -0.39 -4.66 -0.39 7.88e-6 Testicular germ cell tumor; TGCT trans rs1814175 0.817 rs7927373 chr11:49957640 A/C cg15704280 chr7:45808275 SEPT13 -0.73 -8.48 -0.61 5.58e-14 Height; TGCT cis rs597539 0.552 rs10896384 chr11:68720011 A/G cg21963583 chr11:68658836 MRPL21 -0.34 -5.63 -0.45 1.15e-7 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs6912958 0.967 rs6905947 chr6:88161949 C/T cg12350822 chr6:88032061 C6orf162;GJB7 -0.39 -5.0 -0.41 1.91e-6 Monocyte percentage of white cells; TGCT cis rs7091068 0.522 rs10748612 chr10:95494458 G/A cg20715218 chr10:95462985 C10orf4 0.52 5.13 0.42 1.08e-6 Urinary tract infection frequency; TGCT cis rs2072499 0.750 rs55675376 chr1:156165881 C/T cg25208724 chr1:156163844 SLC25A44 1.02 9.51 0.65 2e-16 Testicular germ cell tumor; TGCT cis rs951366 0.764 rs823141 chr1:205741426 T/C cg07167872 chr1:205819463 PM20D1 0.59 7.71 0.57 3.52e-12 Menarche (age at onset); TGCT cis rs11098499 0.863 rs12498539 chr4:120468370 C/T cg09307838 chr4:120376055 NA 0.72 6.87 0.52 2.81e-10 Corneal astigmatism; TGCT cis rs8017423 0.934 rs2401874 chr14:90682467 C/T cg04374321 chr14:90722782 PSMC1 0.77 7.94 0.58 1.06e-12 Mortality in heart failure; TGCT cis rs62244186 0.566 rs2135531 chr3:44881158 C/G cg15687855 chr3:44754131 ZNF502 -0.51 -6.35 -0.5 3.74e-9 Depressive symptoms; TGCT cis rs4642101 0.765 rs1985428 chr3:12829315 A/G cg05775895 chr3:12838266 CAND2 -0.76 -8.55 -0.61 3.82e-14 QRS complex (12-leadsum); TGCT cis rs12477438 0.520 rs7605843 chr2:99811894 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.06 0.84 2.55e-34 Chronic sinus infection; TGCT cis rs17270561 0.943 rs76703022 chr6:25703529 A/C cg16482183 chr6:26056742 HIST1H1C 0.7 4.62 0.38 9.56e-6 Iron status biomarkers; TGCT cis rs875971 0.660 rs13224319 chr7:66007363 A/G cg00343986 chr7:65444356 GUSB 0.23 5.16 0.42 9.66e-7 Aortic root size; TGCT cis rs11785400 0.793 rs9774627 chr8:143731267 G/A cg10596483 chr8:143751796 JRK 0.53 5.21 0.42 7.5e-7 Schizophrenia; TGCT cis rs4253772 0.530 rs9627387 chr22:46684678 A/G cg03482458 chr22:46692211 CN5H6.4;GTSE1 0.7 5.27 0.43 5.83e-7 LDL cholesterol;Cholesterol, total; TGCT trans rs10022799 0.725 rs10003880 chr4:168135438 A/C cg08507725 chr4:8239220 SH3TC1 0.42 7.37 0.55 2.15e-11 Cognitive function; TGCT cis rs8031584 0.697 rs8036176 chr15:31175269 A/G cg08704250 chr15:31115839 NA -0.33 -4.98 -0.41 2.05e-6 Huntington's disease progression; TGCT cis rs4253772 0.637 rs11703173 chr22:46660367 G/A cg24881330 chr22:46731750 TRMU 0.88 4.47 0.37 1.72e-5 LDL cholesterol;Cholesterol, total; TGCT cis rs2970818 0.831 rs7304949 chr12:4609625 A/G cg09670175 chr12:4923468 KCNA6 0.21 4.67 0.39 7.63e-6 Phosphorus levels; TGCT cis rs425277 0.565 rs2480711 chr1:2111376 A/G cg03732007 chr1:2071316 PRKCZ 0.28 6.64 0.51 8.63e-10 Height; TGCT cis rs28785552 0.897 rs10424736 chr19:53239176 G/A cg10871876 chr19:53194124 ZNF83 0.62 8.85 0.62 7.42e-15 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs28595532 1.000 rs55634130 chr4:119655093 C/T cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs858239 0.636 rs28706766 chr7:23169834 T/A cg05602783 chr7:23145260 KLHL7 -0.57 -4.78 -0.39 4.87e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs10791323 0.536 rs1944731 chr11:133726067 G/A cg15485101 chr11:133734466 NA 0.42 5.26 0.43 6.25e-7 Childhood ear infection; TGCT cis rs40363 0.723 rs8060367 chr16:3537919 C/A cg22508957 chr16:3507546 NAT15 -0.51 -4.69 -0.39 7.08e-6 Tuberculosis; TGCT cis rs7618915 0.501 rs34739010 chr3:52766122 A/G cg10802521 chr3:52805072 NEK4 -0.78 -10.0 -0.67 1.26e-17 Bipolar disorder; TGCT cis rs225245 0.791 rs7216391 chr17:34024706 G/A cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs7666738 0.830 rs13147195 chr4:98893334 G/T cg18180107 chr4:99064573 C4orf37 0.53 4.84 0.4 3.83e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1691799 0.831 rs6581678 chr12:66776656 A/G cg16791601 chr12:66731901 HELB -0.27 -5.5 -0.44 2.08e-7 White blood cell count (basophil); TGCT cis rs1858740 0.509 rs196375 chr3:38422919 C/T cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.64 6.02 0.48 1.84e-8 Schizophrenia; TGCT cis rs6831352 0.819 rs2851274 chr4:100025866 G/C cg12011299 chr4:100065546 ADH4 0.41 5.68 0.45 8.93e-8 Alcohol dependence; TGCT cis rs6724607 1.000 rs13006708 chr2:191471428 G/A cg10560079 chr2:191398806 TMEM194B -0.36 -5.07 -0.41 1.4e-6 Pulse pressure; TGCT cis rs13217239 0.646 rs7747454 chr6:27034253 T/G cg26531700 chr6:26746687 NA -0.68 -6.72 -0.52 5.75e-10 Schizophrenia; TGCT cis rs17331151 0.573 rs79664140 chr3:52866936 A/G cg11137980 chr3:52469226 SEMA3G 0.29 5.14 0.42 1.04e-6 Immune reponse to smallpox (secreted IL-2); TGCT trans rs1814175 0.619 rs10769623 chr11:49865926 C/T cg11707556 chr5:10655725 ANKRD33B -0.45 -11.08 -0.71 2.89e-20 Height; TGCT cis rs9902453 0.933 rs8074028 chr17:28461687 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.63 5.41 0.44 3.13e-7 Coffee consumption (cups per day); TGCT cis rs2806561 0.765 rs1738469 chr1:23511407 G/C cg12483005 chr1:23474871 LUZP1 0.39 5.07 0.41 1.44e-6 Height; TGCT cis rs9916302 0.904 rs4794807 chr17:37531718 T/A cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs9611565 0.921 rs4822021 chr22:41726053 G/A cg06634786 chr22:41940651 POLR3H -0.69 -6.38 -0.5 3.26e-9 Vitiligo; TGCT cis rs9796 0.663 rs11853192 chr15:41368515 G/A cg18705301 chr15:41695430 NDUFAF1 -0.52 -6.88 -0.53 2.64e-10 Menopause (age at onset); TGCT cis rs11030122 0.702 rs10835407 chr11:3993231 C/T cg18678763 chr11:4115507 RRM1 0.48 5.64 0.45 1.09e-7 Mean platelet volume;Platelet distribution width; TGCT cis rs6582630 0.519 rs11181294 chr12:38312787 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.54 0.38 1.3e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs981844 0.961 rs56148270 chr4:154660874 C/T cg14289246 chr4:154710475 SFRP2 1.01 8.46 0.6 6.31e-14 Response to statins (LDL cholesterol change); TGCT cis rs12579753 1.000 rs17692461 chr12:82171755 C/G cg07988820 chr12:82153109 PPFIA2 -0.65 -6.79 -0.52 4.09e-10 Resting heart rate; TGCT cis rs473651 0.506 rs561264 chr2:239329979 G/T cg18131467 chr2:239335373 ASB1 0.88 8.17 0.59 3.02e-13 Multiple system atrophy; TGCT cis rs7666738 0.822 rs28367231 chr4:98845726 G/T cg17366294 chr4:99064904 C4orf37 0.7 7.23 0.54 4.35e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs42648 1.000 rs42649 chr7:89977789 A/T cg25739043 chr7:89950458 NA -0.68 -6.7 -0.52 6.58e-10 Homocysteine levels; TGCT cis rs7772486 0.875 rs2328712 chr6:146344563 T/C cg23711669 chr6:146136114 FBXO30 0.84 9.13 0.63 1.59e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs2235642 0.893 rs8051295 chr16:1588087 A/G cg07341220 chr16:1583899 IFT140;TMEM204 -0.3 -4.65 -0.39 8.35e-6 Coronary artery disease; TGCT cis rs610932 0.517 rs670139 chr11:59971795 G/T cg18570331 chr11:60101691 MS4A6E 0.51 4.71 0.39 6.55e-6 Alzheimer's disease; TGCT cis rs62244186 0.748 rs2888410 chr3:44655476 A/C cg11003573 chr3:44754125 ZNF502 -0.41 -4.69 -0.39 6.96e-6 Depressive symptoms; TGCT cis rs936229 0.749 rs8031937 chr15:75181121 A/G cg10253484 chr15:75165896 SCAMP2 -0.76 -6.29 -0.49 4.87e-9 Adverse response to chemotherapy (neutropenia/leucopenia) (carboplatin); TGCT cis rs9611565 0.729 rs132902 chr22:41797758 A/G cg13695892 chr22:41940480 POLR3H -0.9 -8.87 -0.62 6.78e-15 Vitiligo; TGCT cis rs2762353 0.553 rs9467581 chr6:25710548 C/T cg15691649 chr6:25882328 NA 0.5 6.02 0.48 1.84e-8 Blood metabolite levels; TGCT cis rs78461346 1.000 rs75241339 chr17:80527441 A/G cg15014069 chr17:80540666 FOXK2 0.4 5.04 0.41 1.62e-6 3-hydroxypropylmercapturic acid levels in smokers; TGCT cis rs2762353 0.595 rs12207313 chr6:25741027 G/C cg15691649 chr6:25882328 NA 0.44 5.35 0.43 4.12e-7 Blood metabolite levels; TGCT cis rs4862750 0.832 rs6419953 chr4:187900509 T/A cg22105103 chr4:187893119 NA 0.35 4.89 0.4 3.02e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg24675658 chr1:53192096 ZYG11B -0.7 -8.15 -0.59 3.44e-13 Monocyte count; TGCT cis rs6582630 0.502 rs2204008 chr12:38439203 C/T cg26384229 chr12:38710491 ALG10B 0.84 7.5 0.56 1.06e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs4975709 0.589 rs4975745 chr5:1861058 G/C cg14773178 chr5:1868261 NA 0.34 5.8 0.46 5.29e-8 Cardiovascular disease risk factors; TGCT cis rs28386778 0.830 rs2665798 chr17:61921397 C/T cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs2739330 0.828 rs2877178 chr22:24251517 C/T cg20007245 chr22:24372913 LOC391322 -0.72 -7.11 -0.54 8.1e-11 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1799949 1.000 rs3950989 chr17:41237953 G/A cg05368731 chr17:41323189 NBR1 1.18 13.89 0.78 5e-27 Menopause (age at onset); TGCT cis rs73001065 0.901 rs739846 chr19:19419071 G/A cg03709012 chr19:19516395 GATAD2A 0.98 4.78 0.39 4.97e-6 LDL cholesterol; TGCT cis rs826838 0.684 rs12367400 chr12:38618673 G/T cg26384229 chr12:38710491 ALG10B 0.9 8.1 0.59 4.36e-13 Heart rate; TGCT cis rs11209185 0.509 rs12130147 chr1:68446944 G/A cg22082780 chr1:68452167 NA 0.31 4.84 0.4 3.86e-6 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs9435341 0.965 rs2335077 chr1:107573565 A/G cg09367891 chr1:107599246 PRMT6 0.65 5.67 0.45 9.45e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs67311347 1.000 rs112619360 chr3:40432645 T/G cg13683864 chr3:40499215 RPL14 -1.18 -13.2 -0.76 2.14e-25 Renal cell carcinoma; TGCT cis rs514406 0.505 rs431459 chr1:53183230 T/G cg25767906 chr1:53392781 SCP2 -0.47 -5.41 -0.44 3.17e-7 Monocyte count; TGCT cis rs1887596 0.705 rs1087258 chr13:27200006 T/C cg01312412 chr13:27282625 NA 0.29 5.13 0.42 1.1e-6 Facial morphology (factor 3, length of philtrum); TGCT cis rs7659604 0.539 rs56159666 chr4:122782879 G/A cg19748678 chr4:122722346 EXOSC9 0.88 8.76 0.62 1.21e-14 Type 2 diabetes; TGCT cis rs67311347 0.911 rs6776044 chr3:40377503 T/G cg17264618 chr3:40429014 ENTPD3 0.31 4.46 0.37 1.81e-5 Renal cell carcinoma; TGCT cis rs6815814 0.950 rs55830619 chr4:38807364 G/A cg02016764 chr4:38805732 TLR1 -0.35 -5.65 -0.45 1.04e-7 Breast cancer; TGCT cis rs12681287 0.752 rs4310184 chr8:87245253 T/C cg27223183 chr8:87520930 FAM82B -0.83 -5.94 -0.47 2.66e-8 Caudate activity during reward; TGCT cis rs9611565 0.921 rs8137373 chr22:41729216 A/G cg06634786 chr22:41940651 POLR3H 0.69 6.38 0.5 3.26e-9 Vitiligo; TGCT cis rs9906944 0.641 rs11655587 chr17:47140794 C/T cg20966754 chr17:47091339 IGF2BP1 -0.41 -4.44 -0.37 1.98e-5 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs3935685 0.874 rs56370262 chr15:77996708 G/C cg03457338 chr15:78040120 NA -0.22 -5.67 -0.45 9.51e-8 Intelligence (multi-trait analysis); TGCT cis rs1008375 0.900 rs13101742 chr4:17701297 G/A cg18681998 chr4:17616180 MED28 -0.8 -7.47 -0.56 1.22e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs1862618 0.853 rs33322 chr5:56175226 A/G cg24549020 chr5:56110836 MAP3K1 0.7 5.97 0.47 2.34e-8 Initial pursuit acceleration; TGCT cis rs7412746 0.552 rs4970980 chr1:150864992 A/C cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs10504229 0.679 rs17800895 chr8:58050085 A/G cg08280861 chr8:58055591 NA 0.54 6.0 0.47 2.05e-8 Developmental language disorder (linguistic errors); TGCT cis rs2019216 0.542 rs7405615 chr17:21935430 C/G cg22648282 chr17:21454238 C17orf51 -0.59 -5.89 -0.47 3.46e-8 Pelvic organ prolapse; TGCT cis rs3849570 0.925 rs6798680 chr3:81905441 C/A cg07356753 chr3:81810745 GBE1 -0.74 -6.77 -0.52 4.57e-10 Waist circumference;Body mass index; TGCT cis rs12497850 0.931 rs13316620 chr3:49045355 T/C cg07636037 chr3:49044803 WDR6 0.97 10.64 0.69 3.45e-19 Parkinson's disease; TGCT cis rs61990749 0.597 rs10136053 chr14:78155205 G/A cg02301378 chr14:78227641 SNW1;C14orf178 -0.62 -4.59 -0.38 1.09e-5 Fibroblast growth factor basic levels; TGCT cis rs57244997 0.929 rs9346892 chr6:162369314 C/T cg17173639 chr6:162384350 PARK2 -0.41 -4.53 -0.38 1.38e-5 Mosquito bite size; TGCT cis rs12142240 0.698 rs56049453 chr1:46835468 A/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs514406 0.861 rs562182 chr1:53270010 C/T cg01802117 chr1:53393560 SCP2 -0.47 -5.62 -0.45 1.17e-7 Monocyte count; TGCT cis rs1401999 1.000 rs939336 chr3:183685534 A/G cg01324343 chr3:183735012 ABCC5 0.82 10.97 0.7 5.41e-20 Anterior chamber depth; TGCT cis rs7811142 1.000 rs68116612 chr7:100006493 G/A cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs7937682 0.883 rs1612013 chr11:111456293 A/G cg09085632 chr11:111637200 PPP2R1B -0.97 -9.75 -0.66 5.24e-17 Primary sclerosing cholangitis; TGCT cis rs9910055 0.529 rs408282 chr17:42182267 A/G cg19774624 chr17:42201019 HDAC5 0.65 5.98 0.47 2.23e-8 Total body bone mineral density; TGCT cis rs10504229 0.871 rs10504227 chr8:58162005 G/A cg20607798 chr8:58055168 NA 0.45 4.5 0.37 1.52e-5 Developmental language disorder (linguistic errors); TGCT cis rs62103177 0.810 rs62103188 chr18:77627661 G/A cg12964065 chr18:77638022 KCNG2 0.37 4.76 0.39 5.4e-6 Opioid sensitivity; TGCT cis rs9291683 0.609 rs34709913 chr4:10028955 T/C cg11266682 chr4:10021025 SLC2A9 0.66 9.54 0.65 1.61e-16 Bone mineral density; TGCT cis rs4862750 0.872 rs9997374 chr4:187877549 T/A cg03452623 chr4:187889614 NA -0.36 -5.31 -0.43 4.97e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs853679 0.517 rs9380062 chr6:28137569 G/A cg12963246 chr6:28129442 ZNF389 0.52 5.1 0.42 1.23e-6 Depression; TGCT cis rs9611565 0.512 rs2050033 chr22:42159229 G/T cg03806693 chr22:41940476 POLR3H 1.02 10.49 0.69 7.92e-19 Vitiligo; TGCT trans rs1005277 0.579 rs2505237 chr10:38438898 T/G cg17830980 chr10:43048298 ZNF37B -0.87 -11.3 -0.71 8.5e-21 Extrinsic epigenetic age acceleration; TGCT cis rs9660180 1.000 rs9660180 chr1:1723031 G/A cg13866156 chr1:1669148 SLC35E2 -0.23 -5.52 -0.44 1.91e-7 Body mass index; TGCT cis rs4689388 0.926 rs6446480 chr4:6295565 C/T cg00701064 chr4:6280414 WFS1 0.37 4.64 0.38 8.68e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs6540559 1.000 rs12070337 chr1:209992127 G/A cg04352962 chr1:209979756 IRF6 0.65 4.92 0.4 2.65e-6 Cleft lip with or without cleft palate; TGCT cis rs6952808 0.635 rs6952727 chr7:1947958 A/G cg22963979 chr7:1858916 MAD1L1 -0.37 -5.7 -0.46 8.23e-8 Bipolar disorder and schizophrenia; TGCT cis rs6088580 0.570 rs6058057 chr20:33065283 G/A cg08999081 chr20:33150536 PIGU 0.29 5.66 0.45 9.97e-8 Glomerular filtration rate (creatinine); TGCT cis rs6964587 1.000 rs12704635 chr7:91737324 T/G cg22709100 chr7:91322751 NA 0.29 4.79 0.4 4.67e-6 Breast cancer; TGCT cis rs2032447 0.966 rs9358901 chr6:26024436 G/T cg07061783 chr6:25882402 NA -0.53 -5.07 -0.41 1.41e-6 Intelligence (multi-trait analysis); TGCT trans rs7698623 0.717 rs4693893 chr4:88797765 A/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs2439831 0.867 rs76542740 chr15:43891512 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.49 0.44 2.2e-7 Lung cancer in ever smokers; TGCT cis rs9814567 1.000 rs9854299 chr3:134206728 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.62 -0.65 1.04e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs2549003 0.966 rs839 chr5:131819126 C/T cg21138405 chr5:131827807 IRF1 0.19 4.79 0.4 4.64e-6 Asthma (sex interaction); TGCT cis rs858239 0.601 rs4440529 chr7:23168751 G/C cg05602783 chr7:23145260 KLHL7 -0.62 -5.18 -0.42 8.52e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs208520 0.690 rs12189780 chr6:66759619 G/A cg07460842 chr6:66804631 NA 0.96 10.26 0.68 2.92e-18 Exhaled nitric oxide output; TGCT cis rs3829109 0.564 rs13297890 chr9:139274643 C/G cg13741927 chr9:139327495 INPP5E -0.23 -4.94 -0.41 2.46e-6 Peak insulin response;Acute insulin response; TGCT cis rs9916302 0.904 rs6503506 chr17:37524653 C/A cg07936489 chr17:37558343 FBXL20 0.65 5.08 0.41 1.36e-6 Glomerular filtration rate (creatinine); TGCT cis rs1008375 0.646 rs13146455 chr4:17565617 T/G cg18681998 chr4:17616180 MED28 -0.81 -7.32 -0.55 2.73e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10788264 0.513 rs10749455 chr10:124035030 A/G cg09507567 chr10:124027408 NA 0.37 5.31 0.43 5e-7 Total body bone mineral density; TGCT cis rs9788682 1.000 rs61204066 chr15:78815298 G/A cg24631222 chr15:78858424 CHRNA5 0.91 7.89 0.58 1.34e-12 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT cis rs4383453 0.539 rs931575 chr3:123098842 G/C cg04890266 chr3:123102914 ADCY5 -0.5 -8.34 -0.6 1.2e-13 Gestational age at birth (maternal effect); TGCT cis rs2370759 1.000 rs2225152 chr10:32574759 T/C cg01819863 chr10:32635814 EPC1 1.03 10.03 0.67 1.05e-17 Sexual dysfunction (female); TGCT cis rs2153535 0.580 rs1932275 chr6:8442333 T/A cg23788917 chr6:8435910 SLC35B3 0.63 5.58 0.45 1.42e-7 Motion sickness; TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg20007245 chr22:24372913 LOC391322 -0.71 -7.0 -0.53 1.43e-10 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs28386778 0.799 rs12450683 chr17:61984299 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.98 -0.41 2.06e-6 Prudent dietary pattern; TGCT cis rs2836974 0.931 rs2776309 chr21:40715791 A/G cg11644478 chr21:40555479 PSMG1 0.87 7.77 0.57 2.59e-12 Cognitive function; TGCT cis rs10782582 0.609 rs5745547 chr1:76378275 G/C cg03433033 chr1:76189801 ACADM -0.5 -4.88 -0.4 3.15e-6 Daytime sleep phenotypes; TGCT cis rs9311474 0.632 rs6445528 chr3:52572447 C/T cg10802521 chr3:52805072 NEK4 0.76 9.52 0.65 1.86e-16 Electroencephalogram traits; TGCT cis rs2777491 1.000 rs2730057 chr15:41736275 C/A cg18705301 chr15:41695430 NDUFAF1 -0.74 -10.95 -0.7 6.24e-20 Ulcerative colitis; TGCT cis rs4455778 0.543 rs7808690 chr7:49065751 A/C cg26309511 chr7:48887640 NA 0.52 6.8 0.52 3.91e-10 Lung cancer in never smokers; TGCT cis rs10507380 0.824 rs9512631 chr13:27918698 T/C cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs892961 0.932 rs7224116 chr17:75413177 A/G cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs950169 0.580 rs4603535 chr15:85173872 C/T cg11189052 chr15:85197271 WDR73 0.73 6.01 0.47 1.96e-8 Schizophrenia; TGCT cis rs7824557 0.701 rs2060465 chr8:11162609 T/C cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs2836974 0.897 rs8132419 chr21:40527827 C/T cg11644478 chr21:40555479 PSMG1 1.03 11.02 0.7 4.14e-20 Cognitive function; TGCT cis rs7226408 0.948 rs72883570 chr18:34382041 C/T cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs3785574 0.743 rs2727334 chr17:61969063 A/T cg06601766 chr17:61851465 DDX42;CCDC47 0.53 4.45 0.37 1.87e-5 Height; TGCT cis rs1538970 1.000 rs1417578 chr1:45850590 A/G cg05343316 chr1:45956843 TESK2 0.66 5.2 0.42 8.13e-7 Platelet count; TGCT cis rs4253772 0.513 rs6008700 chr22:46722560 C/T cg24881330 chr22:46731750 TRMU 0.94 6.36 0.5 3.54e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs116095464 0.558 rs28558836 chr5:285748 C/G cg22857025 chr5:266934 NA -0.34 -6.64 -0.51 8.6e-10 Breast cancer; TGCT cis rs921968 0.643 rs545460 chr2:219392159 A/G cg02176678 chr2:219576539 TTLL4 0.38 5.48 0.44 2.31e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs7666738 0.830 rs13121558 chr4:99002848 G/A cg17366294 chr4:99064904 C4orf37 0.66 6.54 0.51 1.42e-9 Colonoscopy-negative controls vs population controls; TGCT trans rs6952808 0.582 rs10479762 chr7:2045351 T/C cg24694675 chr1:76082066 NA -0.66 -6.82 -0.52 3.58e-10 Bipolar disorder and schizophrenia; TGCT cis rs9790314 0.521 rs1450522 chr3:161077630 A/G cg03342759 chr3:160939853 NMD3 -0.52 -5.4 -0.44 3.32e-7 Morning vs. evening chronotype; TGCT cis rs877282 0.898 rs71489279 chr10:760510 T/C cg17470449 chr10:769945 NA 0.36 5.35 0.43 4.04e-7 Uric acid levels; TGCT cis rs6582630 0.538 rs8189550 chr12:38333058 T/G cg26384229 chr12:38710491 ALG10B -0.52 -4.46 -0.37 1.84e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs13108904 0.967 rs1316419 chr4:1293997 C/T cg05665937 chr4:1216051 CTBP1 0.25 4.68 0.39 7.33e-6 Obesity-related traits; TGCT cis rs950027 0.549 rs11636114 chr15:45601412 C/G cg26924012 chr15:45694286 SPATA5L1 0.74 7.57 0.56 7.21e-12 Response to fenofibrate (adiponectin levels); TGCT cis rs7617480 0.610 rs10865954 chr3:49211989 T/C cg05785598 chr3:49045655 WDR6 0.39 5.05 0.41 1.57e-6 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs6840360 0.571 rs4696099 chr4:152501951 C/G cg17479576 chr4:152424074 FAM160A1 -0.7 -7.33 -0.55 2.65e-11 Intelligence (multi-trait analysis); TGCT cis rs9733 0.519 rs11204717 chr1:150709129 T/A cg09365446 chr1:150670422 GOLPH3L 0.3 4.53 0.38 1.37e-5 Tonsillectomy; TGCT cis rs17376456 0.825 rs12716454 chr5:93272279 A/C cg25358565 chr5:93447407 FAM172A 1.03 8.1 0.59 4.5e-13 Diabetic retinopathy; TGCT cis rs2230307 0.536 rs534252 chr1:100472604 A/G cg24955406 chr1:100503596 HIAT1 0.75 4.88 0.4 3.2e-6 Carotid intima media thickness; TGCT cis rs1797081 1.000 rs812426 chr10:16857133 C/G cg23933602 chr10:16859644 RSU1 1.08 14.13 0.79 1.3e-27 Platelet distribution width; TGCT cis rs7173743 0.525 rs11856903 chr15:79140017 A/G cg00540400 chr15:79124168 NA -0.17 -4.48 -0.37 1.69e-5 Coronary artery disease; TGCT cis rs782590 0.967 rs782592 chr2:55843875 T/A cg03859395 chr2:55845619 SMEK2 0.75 7.02 0.53 1.26e-10 Metabolic syndrome; TGCT cis rs7818688 0.697 rs11778553 chr8:95978260 C/T cg16049864 chr8:95962084 TP53INP1 0.54 4.65 0.39 8.51e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs11098499 0.738 rs34566984 chr4:120361270 G/A cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs12497850 0.864 rs3212 chr3:49145741 T/C cg18654377 chr3:49208889 KLHDC8B -0.37 -4.69 -0.39 7.12e-6 Parkinson's disease; TGCT cis rs9811920 0.809 rs902159 chr3:99747445 A/G cg07805332 chr3:99536008 MIR548G;C3orf26 -0.43 -4.75 -0.39 5.49e-6 Axial length; TGCT cis rs751728 1.000 rs9380378 chr6:33765479 T/C cg13859433 chr6:33739653 LEMD2 -0.38 -6.69 -0.52 6.82e-10 Crohn's disease; TGCT cis rs12049351 0.774 rs12138965 chr1:229655720 T/C cg12130225 chr1:229698885 NA 0.38 4.63 0.38 8.95e-6 Circulating myeloperoxidase levels (plasma); TGCT cis rs6696846 0.630 rs6692706 chr1:205158561 G/T cg03948781 chr1:205179583 DSTYK 0.35 4.53 0.38 1.38e-5 Red blood cell count; TGCT cis rs586688 0.625 rs606114 chr1:201664101 C/T cg07139329 chr1:201708558 NAV1 0.53 5.35 0.43 4.06e-7 Obesity-related traits; TGCT cis rs9372498 0.505 rs62424173 chr6:118780507 C/G cg07617317 chr6:118971624 C6orf204 0.5 5.39 0.44 3.37e-7 Diastolic blood pressure; TGCT cis rs2836974 0.830 rs2735309 chr21:40715313 C/T cg11644478 chr21:40555479 PSMG1 0.87 7.77 0.57 2.59e-12 Cognitive function; TGCT cis rs8180040 0.739 rs12488225 chr3:47235107 G/A cg27129171 chr3:47204927 SETD2 0.76 9.91 0.66 2.12e-17 Colorectal cancer; TGCT cis rs7172809 0.573 rs74027548 chr15:77512516 T/C cg22256960 chr15:77711686 NA -0.49 -4.62 -0.38 9.51e-6 Glucose homeostasis traits; TGCT cis rs3771570 0.892 rs59715783 chr2:242366262 C/T cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.97e-10 Prostate cancer; TGCT cis rs6500602 0.701 rs4786508 chr16:4568043 G/A cg14951292 chr16:4525986 HMOX2;NMRAL1 0.43 7.54 0.56 8.59e-12 Schizophrenia; TGCT cis rs9527 0.590 rs10786744 chr10:104945028 A/C cg04362960 chr10:104952993 NT5C2 -0.69 -5.96 -0.47 2.41e-8 Arsenic metabolism; TGCT cis rs10858047 0.883 rs72698003 chr1:115080934 C/G cg12756093 chr1:115239321 AMPD1 0.45 4.63 0.38 9.24e-6 Autism; TGCT cis rs79349575 0.721 rs3744608 chr17:46993233 C/G cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs13242816 1.000 rs56063232 chr7:116172808 G/T cg02799643 chr7:116139180 CAV2 -0.43 -5.29 -0.43 5.24e-7 P wave duration; TGCT cis rs9486719 0.947 rs12213375 chr6:96902134 A/G cg18709589 chr6:96969512 KIAA0776 -0.71 -5.21 -0.42 7.61e-7 Migraine;Coronary artery disease; TGCT trans rs8073060 0.586 rs8064895 chr17:34001121 T/C cg19694781 chr19:47549865 TMEM160 -0.6 -13.37 -0.77 8.63e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs11096990 0.679 rs6531707 chr4:39297684 T/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.47 -0.37 1.75e-5 Cognitive function; TGCT cis rs981844 0.712 rs6535956 chr4:154746001 G/A cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs8177253 0.665 rs4525863 chr3:133436136 C/A cg08439880 chr3:133502540 NA -0.27 -4.78 -0.39 4.8e-6 Iron status biomarkers; TGCT cis rs1218582 0.772 rs877343 chr1:154910012 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.19 -0.54 5.48e-11 Prostate cancer; TGCT cis rs6921919 0.583 rs7773051 chr6:28340316 G/A cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.37 -0.43 3.8e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs1975974 1.000 rs67946006 chr17:21723940 T/C cg18423549 chr17:21743878 NA -0.49 -4.76 -0.39 5.3e-6 Psoriasis; TGCT cis rs7095607 0.654 rs12358805 chr10:69960198 T/C cg18986048 chr10:69913749 MYPN 0.48 4.92 0.4 2.73e-6 Lung function (FVC); TGCT cis rs1564271 0.553 rs2489583 chr10:26987698 A/G cg24343755 chr10:26987087 PDSS1 -0.58 -4.87 -0.4 3.3e-6 Overall survival in serous epithelial ovarian cancer treated with paclitaxel and cisplatin; TGCT cis rs3784262 0.740 rs2044071 chr15:58270804 A/G cg12031962 chr15:58353849 ALDH1A2 -0.41 -5.94 -0.47 2.71e-8 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs926938 0.618 rs6693491 chr1:115371061 A/G cg12756093 chr1:115239321 AMPD1 -0.41 -6.02 -0.48 1.79e-8 Autism; TGCT cis rs453301 0.631 rs13250781 chr8:8793343 T/G cg15556689 chr8:8085844 FLJ10661 -0.63 -5.37 -0.43 3.82e-7 Joint mobility (Beighton score); TGCT cis rs1550973 1.000 rs1550973 chr11:131291728 A/G cg01699581 chr11:130356112 NA -0.27 -4.53 -0.38 1.39e-5 Educational attainment (years of education); TGCT cis rs752590 0.806 rs874898 chr2:113974196 C/G cg27425262 chr2:113953981 PSD4;LOC440839 0.39 4.55 0.38 1.24e-5 Mucinous ovarian carcinoma; TGCT cis rs3820068 0.705 rs4645983 chr1:15850603 G/A cg05660106 chr1:15850417 CASP9 1.16 14.82 0.8 3.11e-29 Systolic blood pressure; TGCT cis rs72945132 0.769 rs3781645 chr11:70190374 T/C cg00319359 chr11:70116639 PPFIA1 0.99 7.31 0.55 2.92e-11 Coronary artery disease; TGCT cis rs10419113 0.522 rs13037 chr19:58269173 G/C cg22020399 chr19:58358583 NA -0.32 -4.47 -0.37 1.77e-5 Pediatric bone mineral density (spine); TGCT cis rs1008375 0.800 rs35463363 chr4:17613423 G/T cg16339924 chr4:17578868 LAP3 0.74 5.8 0.46 5.07e-8 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2013441 1.000 rs34644796 chr17:20064128 C/G cg18979559 chr17:20280153 CCDC144C 0.44 4.61 0.38 9.78e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs28622458 chr4:98916651 A/G cg18180107 chr4:99064573 C4orf37 0.53 4.99 0.41 1.98e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs7169223 0.653 rs3743057 chr15:79089007 T/C cg21242079 chr15:79101063 ADAMTS7 0.35 5.66 0.45 9.78e-8 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs2243480 0.901 rs2900904 chr7:65204264 C/G cg18252515 chr7:66147081 NA -1.17 -7.17 -0.54 5.94e-11 Diabetic kidney disease; TGCT cis rs114540395 1.000 rs114540395 chr10:103479062 C/T cg22630918 chr10:102748988 C10orf2 0.41 4.47 0.37 1.72e-5 Schizophrenia; TGCT cis rs6589563 0.737 rs17120029 chr11:116650118 C/T cg20660624 chr11:117307972 DSCAML1 -0.4 -4.98 -0.41 2.11e-6 Eosinophil counts; TGCT cis rs1062177 0.724 rs2964590 chr5:151118146 C/G cg12924095 chr5:151150029 G3BP1 -0.34 -4.97 -0.41 2.17e-6 Preschool internalizing problems; TGCT cis rs1218582 0.510 rs2878411 chr1:154823545 C/T cg16680214 chr1:154839983 KCNN3 -0.26 -4.91 -0.4 2.8e-6 Prostate cancer; TGCT cis rs801193 0.548 rs2659904 chr7:66178602 C/A cg11764359 chr7:65958608 NA 0.62 5.31 0.43 4.97e-7 Aortic root size; TGCT cis rs11098499 0.954 rs7654587 chr4:120388406 C/T cg09307838 chr4:120376055 NA 0.68 6.53 0.51 1.54e-9 Corneal astigmatism; TGCT cis rs3093024 1.000 rs3093023 chr6:167534290 A/G cg07741184 chr6:167504864 NA -0.23 -4.53 -0.38 1.35e-5 Rheumatoid arthritis; TGCT cis rs887829 0.569 rs4399719 chr2:234666461 T/G cg26799339 chr2:234664336 UGT1A10;UGT1A6;UGT1A8;UGT1A4;UGT1A3;UGT1A9;UGT1A7;UGT1A5 -0.26 -4.51 -0.38 1.46e-5 Metabolic traits;Bilirubin levels;Cholelithiasis-related traits in sickle cell anemia;Metabolite levels;Total bilirubin levels in HIV-1 infection;Serum metabolite levels;Blood metabolite levels; TGCT cis rs2836974 0.739 rs12482181 chr21:40548852 A/G cg17971929 chr21:40555470 PSMG1 0.98 9.13 0.63 1.6e-15 Cognitive function; TGCT cis rs57244997 0.727 rs11965957 chr6:162372993 A/C cg17173639 chr6:162384350 PARK2 -0.41 -4.44 -0.37 2e-5 Mosquito bite size; TGCT cis rs1799949 0.965 rs33925201 chr17:41280682 A/G cg10047753 chr17:41438598 NA 0.96 9.6 0.65 1.16e-16 Menopause (age at onset); TGCT cis rs1682825 0.858 rs1836292 chr3:10761255 A/T cg23512531 chr3:10780469 NA 0.64 4.75 0.39 5.42e-6 Economic and political preferences (feminism/equality); TGCT cis rs7267979 0.727 rs4815431 chr20:25532405 T/C cg14121845 chr20:25566513 NINL -0.46 -4.76 -0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1538970 1.000 rs61791368 chr1:45867944 T/C cg05343316 chr1:45956843 TESK2 0.76 5.86 0.47 3.99e-8 Platelet count; TGCT cis rs908922 0.676 rs11205032 chr1:152527690 A/G cg20991723 chr1:152506922 NA 0.44 5.96 0.47 2.38e-8 Hair morphology; TGCT cis rs2739330 0.828 rs5760098 chr22:24248314 A/G cg10150615 chr22:24372951 LOC391322 -1.0 -12.91 -0.76 1.1e-24 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3617 0.591 rs2276823 chr3:52869263 C/A cg11041457 chr3:52719354 GNL3;PBRM1 -0.48 -4.5 -0.37 1.52e-5 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs73198271 1.000 rs11774744 chr8:8607764 A/G ch.8.214553F chr8:8189620 PRAGMIN -0.27 -4.57 -0.38 1.17e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs7666738 0.830 rs2865980 chr4:99027422 T/G cg05340658 chr4:99064831 C4orf37 0.5 5.71 0.46 8.07e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs78487399 0.908 rs7602701 chr2:43841119 A/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.64 4.63 0.38 8.92e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9814567 0.752 rs13075117 chr3:134329535 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.75 6.83 0.52 3.43e-10 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs11718455 1.000 rs11917515 chr3:44020237 A/G cg08738300 chr3:44038990 NA 0.88 6.65 0.51 8.52e-10 Coronary artery disease; TGCT cis rs11098499 0.743 rs10003567 chr4:120241674 C/T cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs72615157 0.664 rs6953580 chr7:99825275 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 0.62 4.95 0.41 2.34e-6 Lung function (FEV1/FVC); TGCT cis rs13217239 0.646 rs9393789 chr6:27067028 G/T cg05738196 chr6:26577821 NA -0.5 -4.77 -0.39 5.05e-6 Schizophrenia; TGCT cis rs595982 0.527 rs12151238 chr19:49368613 T/C cg15549821 chr19:49342101 PLEKHA4 -0.69 -9.25 -0.64 8.09e-16 Red cell distribution width; TGCT cis rs12497850 0.931 rs6446196 chr3:49004723 A/G cg07636037 chr3:49044803 WDR6 0.96 10.52 0.69 6.9e-19 Parkinson's disease; TGCT cis rs4900538 0.963 rs1885708 chr14:102960164 A/G cg18135206 chr14:102964638 TECPR2 0.22 5.19 0.42 8.24e-7 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs13242816 1.000 rs2402078 chr7:116128648 A/C cg02799643 chr7:116139180 CAV2 -0.46 -5.53 -0.44 1.78e-7 P wave duration; TGCT cis rs7017914 0.934 rs17760050 chr8:71574251 A/T cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs739496 0.947 rs34368158 chr12:111846028 C/T cg10833066 chr12:111807467 FAM109A 0.37 4.95 0.41 2.41e-6 Platelet count; TGCT cis rs10892173 0.545 rs115865940 chr11:117666711 C/T cg07621104 chr11:117668040 DSCAML1 0.69 7.61 0.56 5.84e-12 Myopia; TGCT cis rs6582630 0.502 rs11520278 chr12:38359642 T/A cg26384229 chr12:38710491 ALG10B 0.83 7.25 0.55 4e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs9419702 0.538 rs9419628 chr10:133539299 A/C cg20568497 chr10:133558893 NA 0.44 4.7 0.39 6.7e-6 Survival in rectal cancer; TGCT cis rs782590 0.748 rs782634 chr2:55897700 T/C cg18811423 chr2:55921094 PNPT1 0.63 6.3 0.49 4.63e-9 Metabolic syndrome; TGCT cis rs10504229 0.906 rs113745779 chr8:58191301 C/G cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs77741769 0.571 rs3897746 chr12:121324727 A/G cg02419362 chr12:121203948 SPPL3 0.19 4.49 0.37 1.63e-5 Mean corpuscular volume; TGCT cis rs11098499 0.691 rs17009144 chr4:120270795 C/T cg09307838 chr4:120376055 NA -0.57 -5.66 -0.45 1.02e-7 Corneal astigmatism; TGCT cis rs56235845 0.665 rs4976685 chr5:176766177 C/T cg17509989 chr5:176798049 RGS14 -0.57 -7.81 -0.57 2.08e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs57590327 0.555 rs11127740 chr3:81743062 A/C cg07356753 chr3:81810745 GBE1 -0.78 -7.36 -0.55 2.18e-11 Extraversion; TGCT cis rs7772486 0.719 rs2206141 chr6:146086192 A/G cg23711669 chr6:146136114 FBXO30 -0.92 -10.41 -0.68 1.3e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs1018836 0.892 rs4735224 chr8:91567046 C/A cg16814680 chr8:91681699 NA -0.8 -8.57 -0.61 3.46e-14 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs7681440 0.804 rs1442140 chr4:90816023 A/G cg20003494 chr4:90757398 SNCA -0.58 -5.68 -0.45 8.95e-8 Dementia with Lewy bodies; TGCT cis rs6912958 0.547 rs451089 chr6:88041859 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.48 6.35 0.5 3.65e-9 Monocyte percentage of white cells; TGCT cis rs11190604 0.767 rs10883484 chr10:102174803 G/C cg23241863 chr10:102295624 HIF1AN 0.6 4.57 0.38 1.17e-5 Palmitoleic acid (16:1n-7) levels; TGCT cis rs1577917 0.958 rs2324839 chr6:86536942 T/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.68 -5.53 -0.44 1.82e-7 Response to antipsychotic treatment; TGCT cis rs904251 0.523 rs10807184 chr6:37483713 C/T cg01843034 chr6:37503916 NA -0.54 -7.18 -0.54 5.74e-11 Cognitive performance; TGCT cis rs986417 0.818 rs1950315 chr14:61000031 A/C cg27398547 chr14:60952738 C14orf39 1.49 10.78 0.7 1.64e-19 Gut microbiota (bacterial taxa); TGCT cis rs6598955 0.671 rs10902735 chr1:26617936 C/T cg04990556 chr1:26633338 UBXN11 0.64 4.91 0.4 2.78e-6 Obesity-related traits; TGCT cis rs1532993 0.518 rs997658 chr4:98552863 T/C cg05340658 chr4:99064831 C4orf37 -0.42 -5.05 -0.41 1.57e-6 Post bronchodilator FEV1/FVC ratio; TGCT cis rs1215050 0.720 rs7656592 chr4:98624593 G/A cg05340658 chr4:99064831 C4orf37 -0.41 -4.96 -0.41 2.3e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs12681288 0.550 rs4637864 chr8:959761 C/T cg04851639 chr8:1020857 NA -0.27 -4.44 -0.37 1.94e-5 Schizophrenia; TGCT trans rs17834679 1.000 rs17834679 chr19:52270087 C/G cg13034837 chr18:32924525 ZNF24 0.85 6.86 0.52 2.9e-10 Alopecia areata; TGCT cis rs4563143 0.647 rs117946634 chr19:29256822 G/T cg12756686 chr19:29218302 NA 0.76 6.45 0.5 2.29e-9 Methadone dose in opioid dependence; TGCT cis rs28386778 0.897 rs2137144 chr17:61805607 G/A cg26338869 chr17:61819248 STRADA -0.54 -5.03 -0.41 1.71e-6 Prudent dietary pattern; TGCT cis rs2299587 0.554 rs13253029 chr8:17749622 C/T cg04898035 chr8:17640624 MTUS1 -0.2 -4.53 -0.38 1.35e-5 Economic and political preferences; TGCT cis rs595982 0.517 rs10404905 chr19:49406175 A/T cg11637076 chr19:49575188 KCNA7 0.43 5.26 0.43 6.25e-7 Red cell distribution width; TGCT cis rs10504229 0.683 rs56208052 chr8:58130207 A/T cg02725872 chr8:58115012 NA -0.36 -4.95 -0.41 2.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs10736390 0.538 rs12410550 chr1:55107306 A/G cg01517571 chr1:55089959 ACOT11;FAM151A -0.51 -8.92 -0.63 5.16e-15 Survival in pancreatic cancer; TGCT cis rs17376456 0.877 rs12153501 chr5:93360866 T/G cg21475434 chr5:93447410 FAM172A 0.6 4.73 0.39 6.08e-6 Diabetic retinopathy; TGCT cis rs9522267 0.535 rs11069900 chr13:112233285 G/A cg10483660 chr13:112241077 NA -0.26 -4.44 -0.37 1.99e-5 Hepatitis; TGCT cis rs7104764 0.879 rs6598072 chr11:219793 C/T cg18336825 chr11:236787 PSMD13;SIRT3 1.05 10.74 0.69 2e-19 Menarche (age at onset); TGCT cis rs137603 0.603 rs137581 chr22:39677838 C/T cg01093212 chr22:39715156 SNORD43;RPL3 -0.5 -4.69 -0.39 7.15e-6 Primary biliary cholangitis; TGCT cis rs7017914 0.967 rs2732090 chr8:71918257 A/G cg23757474 chr8:71581111 LACTB2;XKR9 0.57 5.31 0.43 4.8e-7 Bone mineral density; TGCT cis rs7811142 0.943 rs111493473 chr7:100049742 A/G cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs3809566 1.000 rs10851721 chr15:63332383 T/C cg08198488 chr15:63333792 TPM1 -0.35 -5.23 -0.43 7e-7 Platelet count; TGCT cis rs7552404 0.731 rs5745445 chr1:76344332 G/A cg03433033 chr1:76189801 ACADM 0.78 7.82 0.57 1.94e-12 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs7822232 0.908 rs1127096 chr8:145140472 A/G cg14631276 chr8:145163102 KIAA1875 -0.56 -5.05 -0.41 1.55e-6 Blood metabolite levels; TGCT cis rs523522 0.962 rs10849754 chr12:120940418 A/C cg12219531 chr12:120966889 COQ5 0.83 7.27 0.55 3.46e-11 High light scatter reticulocyte count; TGCT cis rs1371867 0.846 rs1788206 chr8:101306966 A/G cg00191853 chr8:101177733 SPAG1 -0.22 -4.47 -0.37 1.75e-5 Atrioventricular conduction; TGCT cis rs933688 0.536 rs332537 chr5:90794973 C/T cg12630606 chr5:90679528 LOC100129716;ARRDC3 -1.0 -6.39 -0.5 3.08e-9 Smoking behavior; TGCT cis rs13217239 0.646 rs35691005 chr6:26972070 A/G cg02458000 chr6:26745757 NA 0.5 4.61 0.38 9.84e-6 Schizophrenia; TGCT cis rs62244186 0.593 rs9814298 chr3:44871899 T/A cg25151919 chr3:44754333 ZNF502 -0.45 -5.24 -0.43 6.63e-7 Depressive symptoms; TGCT cis rs2456568 0.933 rs1518577 chr11:93674907 C/T cg26875233 chr11:93583750 C11orf90 -0.45 -5.61 -0.45 1.28e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs28595532 1.000 rs114912871 chr4:119697004 G/C cg14228332 chr4:119757509 SEC24D 1.02 5.06 0.41 1.47e-6 Cannabis dependence symptom count; TGCT cis rs2762353 0.808 rs1185569 chr6:25831603 A/G cg03264133 chr6:25882463 NA -0.61 -6.51 -0.5 1.69e-9 Blood metabolite levels; TGCT cis rs6921919 0.525 rs6929825 chr6:28378959 A/G cg18815343 chr6:28367644 ZSCAN12 -0.54 -5.25 -0.43 6.29e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6918586 0.616 rs198836 chr6:26113616 T/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB -0.7 -6.6 -0.51 1.09e-9 Schizophrenia; TGCT cis rs8016982 0.674 rs8004096 chr14:81701082 T/G cg01989461 chr14:81687754 GTF2A1 0.75 7.01 0.53 1.37e-10 Schizophrenia; TGCT cis rs875971 0.830 rs7799834 chr7:65880694 A/C cg18876405 chr7:65276391 NA 0.32 4.87 0.4 3.29e-6 Aortic root size; TGCT cis rs3796352 0.527 rs11714793 chr3:52924930 A/G cg27565382 chr3:53032988 SFMBT1 0.45 5.21 0.42 7.67e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs3008870 0.916 rs2025608 chr1:67422550 C/T cg03991309 chr1:68237761 GNG12 0.27 4.53 0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs2204008 0.536 rs12368354 chr12:38042798 G/A cg26384229 chr12:38710491 ALG10B 0.85 7.63 0.57 5.5e-12 Bladder cancer; TGCT cis rs1218582 0.741 rs11264281 chr1:154867221 A/G cg09359103 chr1:154839909 KCNN3 -0.74 -16.0 -0.82 6.13e-32 Prostate cancer; TGCT cis rs7178572 1.000 rs62007299 chr15:77711719 G/A cg15453836 chr15:77711506 NA -0.4 -4.56 -0.38 1.22e-5 Type 2 diabetes; TGCT cis rs7772486 0.743 rs9376955 chr6:145949404 T/A cg05347473 chr6:146136440 FBXO30 0.51 4.84 0.4 3.82e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs13124127 chr4:98990729 G/A cg17366294 chr4:99064904 C4orf37 0.68 6.96 0.53 1.75e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs950169 0.580 rs11634322 chr15:85172209 C/T cg12863693 chr15:85201151 NMB 0.46 5.56 0.45 1.6e-7 Schizophrenia; TGCT cis rs483180 0.511 rs496198 chr1:120207177 A/G cg19096424 chr1:120255104 PHGDH -0.56 -5.24 -0.43 6.8e-7 Macular telangiectasia type 2; TGCT cis rs6671200 0.688 rs4950024 chr1:95713499 A/G cg20701556 chr1:95698924 RWDD3 -0.52 -5.34 -0.43 4.26e-7 Stearic acid (18:0) levels; TGCT cis rs12541335 0.639 rs35068739 chr8:22201719 T/C cg02788857 chr8:22132959 PIWIL2 0.28 5.16 0.42 9.54e-7 Hypertriglyceridemia; TGCT cis rs2204008 0.658 rs12371956 chr12:38298010 A/T cg13010199 chr12:38710504 ALG10B 0.57 4.45 0.37 1.89e-5 Bladder cancer; TGCT cis rs10504229 1.000 rs67630725 chr8:58185580 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs10504229 1.000 rs17216957 chr8:58179893 C/T cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs1499614 0.803 rs1922723 chr7:66175063 C/T cg18252515 chr7:66147081 NA -1.26 -7.95 -0.58 9.71e-13 Gout; TGCT cis rs4566357 0.615 rs10174591 chr2:227913140 G/A cg11843606 chr2:227700838 RHBDD1 -0.55 -5.17 -0.42 8.9e-7 Coronary artery disease; TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg22166914 chr1:53195759 ZYG11B 0.37 6.41 0.5 2.77e-9 Monocyte count; TGCT cis rs4372836 0.504 rs7475 chr2:29023749 A/G cg09522027 chr2:28974177 PPP1CB -0.56 -5.68 -0.45 9.2e-8 Body mass index; TGCT cis rs904251 0.523 rs9366935 chr6:37480404 C/T cg01843034 chr6:37503916 NA -0.55 -7.01 -0.53 1.36e-10 Cognitive performance; TGCT cis rs3796619 0.961 rs62294748 chr4:1082999 G/A cg27284194 chr4:1044797 NA 0.46 4.45 0.37 1.85e-5 Recombination rate (males); TGCT cis rs447921 0.861 rs56248611 chr17:74448255 G/A cg09812376 chr17:74270190 QRICH2 -0.45 -4.76 -0.39 5.3e-6 Mitochondrial DNA levels; TGCT cis rs17253792 0.822 rs28392709 chr14:56093685 G/A cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs6460942 0.731 rs75994414 chr7:12307992 C/A cg06484146 chr7:12443880 VWDE -0.54 -4.77 -0.39 5.06e-6 Coronary artery disease; TGCT cis rs7760949 0.963 rs1467729 chr6:13911167 C/T cg27413430 chr6:13925136 RNF182 -0.48 -4.55 -0.38 1.27e-5 Mean corpuscular hemoglobin concentration; TGCT cis rs7044106 0.791 rs735110 chr9:123488940 T/A cg09586646 chr9:123605570 PSMD5;LOC253039 0.49 5.44 0.44 2.74e-7 Hip circumference adjusted for BMI; TGCT cis rs10504229 0.728 rs55812114 chr8:58157453 C/T cg24829409 chr8:58192753 C8orf71 -0.59 -5.18 -0.42 8.54e-7 Developmental language disorder (linguistic errors); TGCT cis rs514406 0.861 rs72637996 chr1:53249618 A/T cg08859206 chr1:53392774 SCP2 0.39 5.78 0.46 5.76e-8 Monocyte count; TGCT cis rs2239547 0.657 rs7620706 chr3:52891756 A/T cg10802521 chr3:52805072 NEK4 -0.65 -6.12 -0.48 1.16e-8 Schizophrenia; TGCT cis rs7674212 0.541 rs2720464 chr4:104073201 G/A cg16532752 chr4:104119610 CENPE -0.57 -5.18 -0.42 8.7e-7 Type 2 diabetes; TGCT cis rs2350702 0.525 rs13030466 chr2:49921390 C/A cg25565504 chr2:50876837 NRXN1 -0.26 -4.53 -0.38 1.37e-5 Morning vs. evening chronotype; TGCT cis rs4478858 0.684 rs12403136 chr1:31728920 A/G cg07478791 chr1:31886160 SERINC2 -0.48 -4.63 -0.38 9.12e-6 Alcohol dependence; TGCT cis rs6459788 0.934 rs10251462 chr7:157258183 C/G cg03453431 chr7:157225567 NA -0.34 -5.12 -0.42 1.13e-6 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs2228479 0.717 rs2286392 chr16:89809549 A/G cg26513180 chr16:89883248 FANCA 0.78 4.54 0.38 1.32e-5 Skin colour saturation; TGCT cis rs28595532 0.920 rs115446044 chr4:119754635 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs6089829 0.962 rs6122350 chr20:61664617 A/G cg08045932 chr20:61659980 NA 0.48 9.28 0.64 7.07e-16 Prostate cancer (SNP x SNP interaction); TGCT cis rs9814567 0.929 rs1863911 chr3:134205231 C/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.99 -9.97 -0.67 1.5e-17 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs9611519 1.000 rs9611510 chr22:41569124 T/C cg13695892 chr22:41940480 POLR3H -0.5 -4.51 -0.38 1.5e-5 Neuroticism; TGCT cis rs4689592 0.503 rs59640165 chr4:7051661 G/A cg26116260 chr4:7069785 GRPEL1 -0.91 -6.77 -0.52 4.48e-10 Monocyte percentage of white cells; TGCT cis rs8177253 1.000 rs8177252 chr3:133480174 C/A cg20276088 chr3:133502917 NA -0.24 -5.06 -0.41 1.5e-6 Iron status biomarkers; TGCT cis rs4285028 0.898 rs73855476 chr3:121633412 A/G cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.62 -0.51 9.73e-10 Multiple sclerosis; TGCT cis rs17270561 1.000 rs79867288 chr6:25828416 A/G cg17042849 chr6:26104293 HIST1H4C -0.91 -6.17 -0.48 9.01e-9 Iron status biomarkers; TGCT cis rs4665809 0.590 rs35656275 chr2:26494695 G/C cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs76878669 0.561 rs4930362 chr11:66154360 T/C cg18002602 chr11:66138449 SLC29A2 0.53 6.49 0.5 1.87e-9 Educational attainment (years of education); TGCT cis rs9611519 0.929 rs4821991 chr22:41440683 T/C cg03806693 chr22:41940476 POLR3H -0.68 -6.1 -0.48 1.25e-8 Neuroticism; TGCT cis rs2180341 0.961 rs7774468 chr6:127592501 G/C cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs28386778 0.897 rs10221279 chr17:61806138 A/G cg22520471 chr17:61851767 DDX42;CCDC47 0.55 4.92 0.4 2.74e-6 Prudent dietary pattern; TGCT cis rs7811142 1.000 rs67163493 chr7:100023838 C/T cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs2836974 0.897 rs34035316 chr21:40594023 T/C cg11644478 chr21:40555479 PSMG1 1.0 10.6 0.69 4.32e-19 Cognitive function; TGCT cis rs4566357 0.787 rs12475134 chr2:227880511 C/T cg11843606 chr2:227700838 RHBDD1 -0.62 -5.32 -0.43 4.59e-7 Coronary artery disease; TGCT cis rs9467711 0.606 rs68112369 chr6:26365759 T/C cg16898833 chr6:26189333 HIST1H4D 1.09 5.25 0.43 6.41e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs4975616 0.869 rs380286 chr5:1320247 G/A cg06550200 chr5:1325588 CLPTM1L -0.3 -4.57 -0.38 1.17e-5 Lung cancer; TGCT cis rs13242816 1.000 rs7796429 chr7:116144369 T/C cg16553024 chr7:116138462 CAV2 -0.44 -5.36 -0.43 3.97e-7 P wave duration; TGCT cis rs9902453 0.933 rs2054846 chr17:28507693 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.73 -6.54 -0.51 1.43e-9 Coffee consumption (cups per day); TGCT cis rs7267979 1.000 rs6083805 chr20:25317356 T/C cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6088580 0.668 rs1205340 chr20:32923871 G/A cg06115741 chr20:33292138 TP53INP2 -0.53 -4.7 -0.39 6.67e-6 Glomerular filtration rate (creatinine); TGCT cis rs9916302 0.610 rs11078902 chr17:37631883 C/G cg15445000 chr17:37608096 MED1 0.31 4.6 0.38 1.01e-5 Glomerular filtration rate (creatinine); TGCT cis rs9677476 0.516 rs59886388 chr2:231995770 G/C cg27665808 chr2:232055229 NA 0.36 4.52 0.38 1.44e-5 Food antigen IgG levels; TGCT cis rs5750830 0.594 rs1010169 chr22:39778167 C/T cg01416388 chr22:39784598 NA 0.62 6.19 0.49 7.9e-9 Intelligence (multi-trait analysis); TGCT cis rs986417 1.000 rs1254296 chr14:60870389 T/C cg27398547 chr14:60952738 C14orf39 -1.42 -8.68 -0.61 1.89e-14 Gut microbiota (bacterial taxa); TGCT cis rs10256972 0.567 rs2949185 chr7:1209013 A/G cg17775962 chr7:1200435 ZFAND2A 0.27 4.63 0.38 9.19e-6 Longevity;Endometriosis; TGCT cis rs1153858 1.000 rs1145091 chr15:45649996 A/G cg26924012 chr15:45694286 SPATA5L1 0.99 12.23 0.74 4.74e-23 Homoarginine levels; TGCT cis rs12220898 0.568 rs4838376 chr10:50482048 T/C cg06072769 chr10:50146962 WDFY4 0.39 5.1 0.42 1.23e-6 Inflammatory biomarkers; TGCT cis rs7726839 0.561 rs11955068 chr5:582324 C/T cg09021430 chr5:549028 NA -0.37 -5.23 -0.42 7.12e-7 Obesity-related traits; TGCT cis rs10504229 1.000 rs57624567 chr8:58176995 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs17221829 0.965 rs7927936 chr11:89460495 C/G cg02982614 chr11:89391479 FOLH1B -0.3 -5.15 -0.42 9.89e-7 Anxiety in major depressive disorder; TGCT cis rs7193541 0.684 rs7191665 chr16:74688948 T/G cg01733217 chr16:74700730 RFWD3 0.99 13.32 0.77 1.14e-25 Multiple myeloma; TGCT cis rs4645881 0.748 rs1010103 chr19:49461211 T/G cg15040422 chr19:49955266 ALDH16A1;PIH1D1 0.82 4.51 0.38 1.47e-5 Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil counts; TGCT cis rs9926296 0.744 rs164746 chr16:89709019 C/T cg01097406 chr16:89675127 NA 0.34 6.23 0.49 6.76e-9 Vitiligo; TGCT cis rs67311347 1.000 rs9827461 chr3:40489351 T/A cg17264618 chr3:40429014 ENTPD3 0.34 4.98 0.41 2.05e-6 Renal cell carcinoma; TGCT cis rs61931739 0.500 rs3934517 chr12:34451396 T/C cg06521331 chr12:34319734 NA -0.28 -4.51 -0.38 1.47e-5 Morning vs. evening chronotype; TGCT cis rs17607347 0.542 rs62051130 chr16:72455938 C/T cg06220725 chr16:72042591 DHODH -0.72 -4.77 -0.39 5e-6 Intelligence (multi-trait analysis); TGCT cis rs6695640 0.756 rs1555661 chr1:17730812 A/G cg25979543 chr1:17888104 ARHGEF10L -0.25 -4.57 -0.38 1.14e-5 Mean platelet volume; TGCT cis rs12044355 0.516 rs2356383 chr1:231742973 G/C cg04892437 chr1:231737901 TSNAX-DISC1 -0.51 -5.04 -0.41 1.58e-6 Alzheimer's disease; TGCT cis rs8179 0.645 rs2282979 chr7:92264993 T/C cg15732164 chr7:92237376 CDK6 -0.27 -4.66 -0.39 8.16e-6 Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Neutrophil count;White blood cell count;Myeloid white cell count;Granulocyte count;White blood cell count (basophil); TGCT cis rs10479542 0.503 rs12719865 chr5:178993566 C/T cg21226059 chr5:178986404 RUFY1 0.51 5.52 0.44 1.93e-7 Lung cancer; TGCT cis rs2456568 0.803 rs10831140 chr11:93640689 G/A cg14065697 chr11:93583672 C11orf90 -0.36 -4.46 -0.37 1.83e-5 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs6545883 0.929 rs10193666 chr2:61629408 C/T cg15711740 chr2:61764176 XPO1 0.53 4.7 0.39 6.67e-6 Tuberculosis; TGCT cis rs12643440 0.538 rs2314601 chr4:17139932 C/T cg22650099 chr4:17144496 NA -0.46 -4.66 -0.39 7.88e-6 Metabolite levels (Pyroglutamine); TGCT cis rs4455778 0.659 rs12530914 chr7:49026076 T/C cg26309511 chr7:48887640 NA -0.44 -5.22 -0.42 7.26e-7 Lung cancer in never smokers; TGCT cis rs79349575 0.783 rs15563 chr17:47005193 A/G cg07967210 chr17:47022446 SNF8 0.4 5.5 0.44 2.11e-7 Type 2 diabetes; TGCT cis rs12497850 0.829 rs12636030 chr3:49182237 A/G cg07636037 chr3:49044803 WDR6 0.94 9.88 0.66 2.51e-17 Parkinson's disease; TGCT cis rs10838634 1.000 rs4128315 chr11:46837201 T/C cg18332754 chr11:46939436 LRP4 0.89 4.46 0.37 1.82e-5 Schizophrenia; TGCT cis rs2658782 0.950 rs2446061 chr11:93149277 C/T cg18152523 chr11:93063302 CCDC67 -0.69 -5.41 -0.44 3.11e-7 Pulmonary function decline; TGCT cis rs2839186 0.504 rs4347941 chr21:47938239 T/C cg12379764 chr21:47803548 PCNT 0.5 5.96 0.47 2.39e-8 Testicular germ cell tumor; TGCT cis rs10435719 0.610 rs80269926 chr8:11790527 T/C cg02840367 chr8:11660030 FDFT1 -0.54 -4.52 -0.38 1.45e-5 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs7681440 0.904 rs1372521 chr4:90765223 G/A cg14346243 chr4:90757452 SNCA -0.57 -5.6 -0.45 1.31e-7 Dementia with Lewy bodies; TGCT cis rs2688608 0.618 rs28553894 chr10:75489843 C/A cg04320760 chr10:75533139 FUT11 -0.39 -6.01 -0.48 1.89e-8 Inflammatory bowel disease; TGCT cis rs6964587 1.000 rs12333563 chr7:91667326 G/A cg22709100 chr7:91322751 NA 0.28 4.56 0.38 1.19e-5 Breast cancer; TGCT cis rs9611565 0.921 rs3927 chr22:41722864 A/G cg03806693 chr22:41940476 POLR3H -0.98 -10.9 -0.7 8.34e-20 Vitiligo; TGCT cis rs8141529 0.584 rs58004020 chr22:29257050 A/T cg02153584 chr22:29168773 CCDC117 0.63 5.17 0.42 9.2e-7 Lymphocyte counts; TGCT cis rs10479542 0.784 rs6896940 chr5:178985994 G/C cg00080972 chr5:178986291 RUFY1 0.59 7.77 0.57 2.62e-12 Lung cancer; TGCT cis rs4699052 0.963 rs2085978 chr4:104193614 A/G cg16532752 chr4:104119610 CENPE -0.52 -4.76 -0.39 5.34e-6 Testicular germ cell tumor; TGCT cis rs17601876 0.814 rs2899474 chr15:51562076 C/T cg19946085 chr15:51559439 CYP19A1 -0.33 -5.06 -0.41 1.45e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs9611565 0.921 rs2281332 chr22:41746212 T/C cg06634786 chr22:41940651 POLR3H -0.63 -6.01 -0.47 1.93e-8 Vitiligo; TGCT cis rs2032447 0.901 rs2213284 chr6:26031868 G/A cg07061783 chr6:25882402 NA -0.56 -5.37 -0.43 3.72e-7 Intelligence (multi-trait analysis); TGCT cis rs916888 0.821 rs199504 chr17:44861003 C/T cg16520312 chr17:43971471 MAPT;LOC100128977 0.55 4.75 0.39 5.52e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs11098499 0.954 rs7436506 chr4:120393769 T/C cg09307838 chr4:120376055 NA 0.68 6.37 0.5 3.41e-9 Corneal astigmatism; TGCT cis rs57590327 0.516 rs66665538 chr3:81796391 T/A cg07356753 chr3:81810745 GBE1 -0.79 -6.52 -0.51 1.56e-9 Extraversion; TGCT cis rs7635838 0.718 rs2606736 chr3:11400249 C/T cg00170343 chr3:11313890 ATG7 0.66 6.47 0.5 2.01e-9 HDL cholesterol; TGCT cis rs4803468 1.000 rs284657 chr19:41929915 G/C cg09537434 chr19:41945824 ATP5SL -0.92 -10.72 -0.69 2.27e-19 Height; TGCT cis rs6430585 0.528 rs115469964 chr2:136696608 A/C cg07169764 chr2:136633963 MCM6 1.26 12.74 0.75 2.79e-24 Corneal structure; TGCT cis rs9914544 1.000 rs1737944 chr17:18840433 G/A cg26378065 chr17:18585709 ZNF286B 0.53 4.74 0.39 5.79e-6 Educational attainment (years of education); TGCT cis rs9916302 0.752 rs9901219 chr17:37558369 T/G cg07936489 chr17:37558343 FBXL20 0.91 7.57 0.56 7.21e-12 Glomerular filtration rate (creatinine); TGCT cis rs9522267 0.502 rs9515450 chr13:112234262 T/C cg10483660 chr13:112241077 NA -0.27 -4.61 -0.38 9.87e-6 Hepatitis; TGCT cis rs4970988 0.640 rs7524734 chr1:150655686 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.74e-6 Urate levels; TGCT cis rs72615157 0.634 rs79986079 chr7:99802044 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 0.63 5.05 0.41 1.57e-6 Lung function (FEV1/FVC); TGCT cis rs2243480 1.000 rs13310597 chr7:65598540 A/G cg07424592 chr7:64974309 NA 1.26 7.79 0.57 2.25e-12 Diabetic kidney disease; TGCT cis rs9322193 0.884 rs9689702 chr6:150061856 G/A cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs12497850 1.000 rs10865952 chr3:48744484 A/G cg16497277 chr3:49208875 KLHDC8B -0.5 -4.78 -0.39 4.87e-6 Parkinson's disease; TGCT cis rs1075232 0.655 rs80220087 chr15:31555817 G/A cg01030201 chr15:31746330 NA -0.87 -4.48 -0.37 1.69e-5 Survival in colorectal cancer (non-distant metastatic); TGCT cis rs854765 0.547 rs9913277 chr17:17919749 G/T cg24612305 chr17:17875800 TOM1L2;LRRC48 0.79 8.41 0.6 8.09e-14 Total body bone mineral density; TGCT trans rs17685 0.753 rs55812043 chr7:75747241 T/C cg19862616 chr7:65841803 NCRNA00174 0.52 9.01 0.63 3.02e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs910316 1.000 rs7147118 chr14:75610170 G/C cg08847533 chr14:75593920 NEK9 0.96 10.86 0.7 1.05e-19 Height; TGCT cis rs380904 0.552 rs10099003 chr8:144645460 C/T cg12686110 chr8:144635478 GSDMD 0.57 4.44 0.37 1.98e-5 Venous thromboembolism (SNP x SNP interaction); TGCT cis rs2455601 0.573 rs2653573 chr11:8989874 C/G cg21881798 chr11:8931708 C11orf17;ST5 -0.49 -5.09 -0.42 1.31e-6 Schizophrenia; TGCT cis rs514406 0.679 rs545719 chr1:53304922 T/C cg16325326 chr1:53192061 ZYG11B 0.57 6.24 0.49 6.31e-9 Monocyte count; TGCT cis rs3820068 0.603 rs3795763 chr1:15959977 C/T cg05660106 chr1:15850417 CASP9 0.83 8.19 0.59 2.78e-13 Systolic blood pressure; TGCT cis rs651907 0.557 rs56291106 chr3:101377474 C/T cg21474964 chr3:101395104 ZBTB11;LOC100009676 0.91 10.9 0.7 8.24e-20 Colorectal cancer; TGCT cis rs10782582 0.593 rs1412717 chr1:76125471 C/T cg10523679 chr1:76189770 ACADM -0.68 -7.05 -0.53 1.11e-10 Daytime sleep phenotypes; TGCT cis rs7296418 0.961 rs1790106 chr12:123591596 G/T cg00376283 chr12:123451042 ABCB9 0.84 7.68 0.57 4.11e-12 Platelet count; TGCT trans rs1814175 0.754 rs28593359 chr11:50042357 C/T cg03929089 chr4:120376271 NA -0.72 -8.55 -0.61 3.8e-14 Height; TGCT cis rs7542091 0.704 rs9429825 chr1:210052133 C/G cg21951975 chr1:209979733 IRF6 0.59 5.89 0.47 3.41e-8 Monobrow; TGCT cis rs6095298 0.595 rs34326966 chr20:47436646 C/A cg12307787 chr20:48099359 KCNB1 0.44 4.63 0.38 8.96e-6 Intelligence (multi-trait analysis); TGCT cis rs5769707 0.656 rs135875 chr22:50012419 T/G cg05373962 chr22:49881684 NA -0.29 -4.97 -0.41 2.16e-6 Monocyte count;Monocyte percentage of white cells; TGCT cis rs7666738 0.830 rs11722272 chr4:99000839 C/T cg05340658 chr4:99064831 C4orf37 0.5 5.44 0.44 2.7e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs56235845 0.694 rs4532376 chr5:176774403 G/A cg16006841 chr5:176797999 RGS14 0.52 7.69 0.57 3.9e-12 Hemoglobin concentration;Hematocrit; TGCT cis rs1215050 0.791 rs155019 chr4:98759126 G/A cg17366294 chr4:99064904 C4orf37 0.52 5.61 0.45 1.27e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs1018836 0.812 rs10808619 chr8:91622916 A/T cg16814680 chr8:91681699 NA -0.78 -8.2 -0.59 2.54e-13 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2836974 0.799 rs8129303 chr21:40711959 G/A cg06238570 chr21:40685208 BRWD1 0.65 5.67 0.45 9.37e-8 Cognitive function; TGCT cis rs7811142 1.000 rs11761725 chr7:100039815 C/T cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.95 8.0 0.58 7.67e-13 Platelet count; TGCT cis rs2463822 1.000 rs2513747 chr11:62098735 T/C cg23876832 chr11:62092739 NA 0.67 4.91 0.4 2.82e-6 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs2046867 0.908 rs9880763 chr3:72789805 G/C cg25664220 chr3:72788482 NA -0.54 -6.8 -0.52 3.96e-10 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs514406 0.767 rs551591 chr1:53301876 A/G cg08859206 chr1:53392774 SCP2 -0.46 -6.97 -0.53 1.62e-10 Monocyte count; TGCT cis rs11122272 0.701 rs2474628 chr1:231526000 C/T cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.7 -6.94 -0.53 1.98e-10 Hemoglobin concentration; TGCT cis rs6570726 0.967 rs418662 chr6:145848832 A/C cg23711669 chr6:146136114 FBXO30 0.7 6.34 0.49 3.98e-9 Lobe attachment (rater-scored or self-reported); TGCT cis rs1847505 0.609 rs1514541 chr13:61586096 C/G cg25164009 chr13:61490935 NA -0.31 -4.84 -0.4 3.85e-6 Polychlorinated biphenyl levels; TGCT cis rs739496 0.579 rs2158030 chr12:112285591 T/C cg10833066 chr12:111807467 FAM109A 0.38 5.41 0.44 3.08e-7 Platelet count; TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg11965913 chr1:205819406 PM20D1 -0.48 -6.79 -0.52 4.05e-10 Menarche (age at onset); TGCT cis rs7178572 0.568 rs12906708 chr15:77681444 A/G cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs2658782 0.724 rs2658770 chr11:93261886 A/G cg15737290 chr11:93063684 CCDC67 0.7 5.2 0.42 8e-7 Pulmonary function decline; TGCT cis rs3812831 0.695 rs422149 chr13:114931086 T/G cg06611532 chr13:114900021 NA 0.35 6.42 0.5 2.57e-9 Schizophrenia; TGCT trans rs2288327 0.557 rs60488846 chr2:179357842 C/T cg14011486 chr1:26737247 LIN28 1.03 7.28 0.55 3.41e-11 Atrial fibrillation; TGCT cis rs1801251 0.964 rs6748027 chr2:233629552 T/C cg25237894 chr2:233734115 C2orf82 0.32 5.88 0.47 3.5e-8 Coronary artery disease; TGCT cis rs6088590 0.648 rs6058105 chr20:33271719 C/T cg06115741 chr20:33292138 TP53INP2 0.59 5.23 0.43 6.91e-7 Coronary artery disease; TGCT cis rs7570971 1.000 rs7570971 chr2:135837906 C/A cg07169764 chr2:136633963 MCM6 0.55 4.92 0.4 2.66e-6 Blood metabolite levels;Body mass index;Cholesterol, total; TGCT cis rs62103177 0.714 rs12607447 chr18:77605212 A/G cg12964065 chr18:77638022 KCNG2 0.33 4.63 0.38 9.06e-6 Opioid sensitivity; TGCT cis rs2172802 1.000 rs2172802 chr4:62453209 C/T cg04118610 chr4:62707027 LPHN3 0.42 4.88 0.4 3.25e-6 Partial epilepsies; TGCT cis rs7698623 0.717 rs1463094 chr4:88792584 G/A cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs6912958 0.754 rs10755484 chr6:88244648 C/T cg08069147 chr6:88032118 GJB7;C6orf162 -0.53 -5.07 -0.41 1.41e-6 Monocyte percentage of white cells; TGCT cis rs7666738 0.712 rs34043080 chr4:99008748 G/C cg05340658 chr4:99064831 C4orf37 0.49 5.61 0.45 1.28e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7089973 0.604 rs11196939 chr10:116593175 A/G cg03647239 chr10:116582469 FAM160B1 -0.6 -5.83 -0.46 4.6e-8 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs4886920 0.519 rs4496098 chr15:78117937 C/G cg25212270 chr15:78015279 NA 0.34 5.02 0.41 1.77e-6 Neuroticism; TGCT cis rs9400467 0.537 rs12212282 chr6:111524838 T/C cg15721981 chr6:111408429 SLC16A10 0.73 4.79 0.4 4.71e-6 Blood metabolite levels;Amino acid levels; TGCT cis rs7113874 0.569 rs10444316 chr11:8534614 G/A cg14521421 chr11:8862019 ST5 0.28 4.48 0.37 1.64e-5 Body mass index in physically active individuals;Body mass index (joint analysis main effects and physical activity interaction); TGCT cis rs7267979 0.966 rs2482918 chr20:25412135 C/T cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8032315 1.000 rs8032315 chr15:91418297 A/T cg04510874 chr15:91427884 FES 0.46 5.46 0.44 2.55e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs7172809 0.897 rs869302 chr15:77830430 T/C cg22256960 chr15:77711686 NA -0.47 -4.76 -0.39 5.23e-6 Glucose homeostasis traits; TGCT cis rs2456568 0.606 rs11020616 chr11:93691594 C/T cg16099599 chr11:93583650 C11orf90 0.42 4.97 0.41 2.17e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs3008870 1.000 rs11208976 chr1:67434411 A/G cg03991309 chr1:68237761 GNG12 -0.27 -4.53 -0.38 1.36e-5 Lymphocyte percentage of white cells; TGCT cis rs9899728 1.000 rs7222902 chr17:73019710 T/A cg00012762 chr17:72744649 SLC9A3R1 -1.0 -4.49 -0.37 1.59e-5 Alzheimer's disease or small vessel stroke; TGCT cis rs9291683 0.588 rs4280729 chr4:10013861 C/T cg11266682 chr4:10021025 SLC2A9 0.73 10.86 0.7 1.03e-19 Bone mineral density; TGCT cis rs769267 0.931 rs2965197 chr19:19470910 C/T cg20644253 chr19:19431407 KIAA0892;SF4 -0.73 -6.5 -0.5 1.8e-9 Tonsillectomy; TGCT cis rs924043 0.636 rs80251809 chr6:170382335 G/A cg17426568 chr6:170418587 NA 0.44 4.48 0.37 1.69e-5 Type 1 diabetes; TGCT cis rs910316 0.967 rs2010678 chr14:75567178 C/T cg23033748 chr14:75592666 NEK9 0.27 4.57 0.38 1.16e-5 Height; TGCT cis rs875971 0.638 rs35986979 chr7:66088990 G/A cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs1005277 0.579 rs2023351 chr10:38378814 A/G cg25427524 chr10:38739819 LOC399744 -0.39 -7.9 -0.58 1.31e-12 Extrinsic epigenetic age acceleration; TGCT cis rs317689 0.690 rs7969559 chr12:69655167 A/G cg14784868 chr12:69753453 YEATS4 0.52 4.5 0.37 1.55e-5 Response to diuretic therapy; TGCT cis rs12479064 0.703 rs28382977 chr2:100018304 G/A cg26064155 chr2:99771622 LIPT1;TSGA10 -0.58 -4.71 -0.39 6.5e-6 Chronic sinus infection; TGCT cis rs2692947 0.537 rs1364394 chr2:96195730 A/G cg23100626 chr2:96804247 ASTL -0.44 -5.06 -0.41 1.47e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7178572 0.568 rs7176302 chr15:77671216 C/G cg15453836 chr15:77711506 NA -0.42 -4.78 -0.39 4.92e-6 Type 2 diabetes; TGCT cis rs617219 0.671 rs1316753 chr5:78531337 G/C cg05890484 chr5:78407552 BHMT 0.34 4.63 0.38 8.97e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs2486288 0.656 rs8039354 chr15:45551756 A/G cg26924012 chr15:45694286 SPATA5L1 0.72 7.46 0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs910187 0.678 rs6124964 chr20:45812536 T/G cg27589058 chr20:45804311 EYA2 -0.34 -7.21 -0.54 4.78e-11 Migraine; TGCT cis rs3749237 1.000 rs3749237 chr3:49770032 C/T cg03060546 chr3:49711283 APEH 0.72 7.38 0.55 2.02e-11 Resting heart rate; TGCT trans rs62103177 0.673 rs62096717 chr18:77616819 C/T cg05926928 chr17:57297772 GDPD1 1.06 10.79 0.7 1.52e-19 Opioid sensitivity; TGCT cis rs868036 0.718 rs2241420 chr15:68082816 G/A cg05925327 chr15:68127851 NA -0.5 -4.86 -0.4 3.4e-6 Restless legs syndrome; TGCT cis rs9911578 1.000 rs3744109 chr17:56594197 C/T cg05425664 chr17:57184151 TRIM37 0.63 6.26 0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs3796352 1.000 rs35507120 chr3:53053924 C/T cg27565382 chr3:53032988 SFMBT1 0.45 4.58 0.38 1.14e-5 Immune reponse to smallpox (secreted IL-2); TGCT cis rs6582630 0.519 rs7294292 chr12:38349540 C/T cg13010199 chr12:38710504 ALG10B 0.58 4.52 0.38 1.41e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg06873352 chr17:61820015 STRADA 0.55 5.8 0.46 5.25e-8 Prudent dietary pattern; TGCT trans rs9650657 0.515 rs7820860 chr8:10950396 C/G cg06636001 chr8:8085503 FLJ10661 -0.76 -6.92 -0.53 2.11e-10 Neuroticism; TGCT cis rs854765 0.506 rs7210400 chr17:17949957 C/T cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.8 -8.46 -0.61 6.18e-14 Total body bone mineral density; TGCT cis rs1322512 0.920 rs2695246 chr6:152948466 T/C cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs228437 0.586 rs9402621 chr6:134937671 A/G cg09872934 chr6:134495829 SGK1 0.53 4.6 0.38 1.03e-5 Melanoma; TGCT cis rs4455778 0.659 rs4917195 chr7:49021597 T/G cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs4961252 0.505 rs12680168 chr8:142102522 A/T cg09914555 chr8:142094789 NA -0.39 -5.74 -0.46 6.97e-8 Isovolumetric relaxation time;Response to interferon beta therapy; TGCT cis rs763014 1.000 rs2269558 chr16:682250 C/T cg27436995 chr16:743998 FBXL16 -0.47 -5.17 -0.42 9.29e-7 Height; TGCT cis rs7640424 0.502 rs326359 chr3:107820619 G/A cg09227934 chr3:107805635 CD47 0.23 4.82 0.4 4.08e-6 Body mass index; TGCT cis rs2836974 0.932 rs56306759 chr21:40608106 G/A cg11890956 chr21:40555474 PSMG1 1.1 12.31 0.74 2.99e-23 Cognitive function; TGCT cis rs7772486 0.790 rs1062067 chr6:146207563 A/G cg23711669 chr6:146136114 FBXO30 0.89 10.18 0.67 4.61e-18 Lobe attachment (rater-scored or self-reported); TGCT cis rs7666738 0.830 rs10031751 chr4:98939134 G/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs10782582 0.593 rs6673786 chr1:76149637 C/T cg22875332 chr1:76189707 ACADM -0.55 -6.28 -0.49 5.25e-9 Daytime sleep phenotypes; TGCT trans rs525455 1.000 rs525455 chr10:13103285 C/T cg21721093 chr17:8906386 NA 0.66 6.85 0.52 3.03e-10 Platelet aggregation; TGCT cis rs514406 0.698 rs567880 chr1:53348564 T/G cg01802117 chr1:53393560 SCP2 -0.46 -5.81 -0.46 4.91e-8 Monocyte count; TGCT cis rs56104184 0.830 rs17272645 chr19:49342366 C/G cg15549821 chr19:49342101 PLEKHA4 0.91 15.12 0.81 6.49e-30 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs7811142 0.830 rs11768967 chr7:99967644 G/A cg23667466 chr7:100026434 MEPCE;ZCWPW1 0.85 7.0 0.53 1.44e-10 Platelet count; TGCT cis rs2243480 1.000 rs778679 chr7:65840911 A/G cg07424592 chr7:64974309 NA 1.27 7.28 0.55 3.29e-11 Diabetic kidney disease; TGCT trans rs9985766 1.000 rs9968351 chr4:151022261 G/A cg02993991 chr19:4064177 ZBTB7A 0.57 6.7 0.52 6.59e-10 Coronary artery disease;Myocardial infarction; TGCT cis rs28595532 0.920 rs115738062 chr4:119725490 C/T cg21605333 chr4:119757512 SEC24D 1.72 8.96 0.63 3.99e-15 Cannabis dependence symptom count; TGCT cis rs1348850 0.914 rs7573763 chr2:178249808 C/T cg22681709 chr2:178499509 PDE11A -0.35 -4.57 -0.38 1.15e-5 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs2594989 0.887 rs9850117 chr3:11571991 C/T cg26283222 chr3:11613257 VGLL4 0.22 4.71 0.39 6.61e-6 Circulating chemerin levels; TGCT cis rs11167764 0.895 rs6882824 chr5:141474300 A/G cg08523384 chr5:141488047 NDFIP1 -0.24 -4.81 -0.4 4.26e-6 Crohn's disease; TGCT cis rs10876993 0.890 rs2640630 chr12:58067267 T/C cg15848620 chr12:58087721 OS9 -0.72 -5.91 -0.47 3.12e-8 Celiac disease or Rheumatoid arthritis; TGCT cis rs17122693 1.000 rs35014209 chr14:51054598 A/G cg04730355 chr14:51134070 SAV1 1.23 8.63 0.61 2.45e-14 Cognitive performance; TGCT trans rs916888 0.687 rs199456 chr17:44797919 C/T cg22433210 chr17:43662623 NA 1.05 7.4 0.55 1.83e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6740322 0.895 rs6738717 chr2:43573670 C/T cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -6.58 -0.51 1.17e-9 Coronary artery disease; TGCT cis rs12142240 0.698 rs41294458 chr1:46810304 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.81 -0.4 4.34e-6 Menopause (age at onset); TGCT cis rs2594989 0.943 rs7349536 chr3:11442503 C/T cg00170343 chr3:11313890 ATG7 -0.67 -5.05 -0.41 1.57e-6 Circulating chemerin levels; TGCT cis rs7666738 0.830 rs62321587 chr4:98997958 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2235642 0.821 rs2281236 chr16:1603576 G/A cg11375102 chr16:1583810 IFT140;TMEM204 -0.3 -5.42 -0.44 2.97e-7 Coronary artery disease; TGCT cis rs7666738 0.716 rs6814353 chr4:99074202 A/G cg18180107 chr4:99064573 C4orf37 0.59 5.27 0.43 5.8e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7824557 0.602 rs11781375 chr8:11204532 A/G cg21775007 chr8:11205619 TDH 0.72 7.02 0.53 1.27e-10 Retinal vascular caliber; TGCT cis rs7953508 0.506 rs10777530 chr12:93961110 C/T cg18151635 chr12:93972918 NA -0.2 -4.66 -0.39 8.15e-6 Pubertal anthropometrics; TGCT cis rs1034435 0.755 rs9615336 chr22:48893090 G/C cg05992904 chr22:48892994 FAM19A5 -0.34 -4.65 -0.39 8.37e-6 Late-onset Alzheimer's disease; TGCT cis rs12681287 0.547 rs7837569 chr8:87507366 C/T cg19078186 chr8:87526527 CPNE3 -0.37 -4.57 -0.38 1.15e-5 Caudate activity during reward; TGCT cis rs933688 0.941 rs6452954 chr5:90735692 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.01 9.89 0.66 2.31e-17 Smoking behavior; TGCT cis rs57221529 0.766 rs12522140 chr5:587261 C/A cg09021430 chr5:549028 NA -0.37 -4.98 -0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs1480597 0.518 rs10751358 chr10:45199194 A/G cg12063947 chr10:45878068 ALOX5 0.26 4.44 0.37 2e-5 Parkinson's disease; TGCT cis rs17374749 0.916 rs9855601 chr3:136768482 T/C cg12473912 chr3:136751656 NA -0.48 -7.82 -0.57 1.98e-12 Anxiety in major depressive disorder; TGCT cis rs4919044 0.674 rs115089490 chr10:94793496 G/C cg05127821 chr10:94822908 CYP26C1 -0.75 -4.75 -0.39 5.59e-6 Coronary artery disease; TGCT cis rs2197308 0.565 rs4123923 chr12:37857684 T/C cg13010199 chr12:38710504 ALG10B 0.64 5.15 0.42 9.73e-7 Morning vs. evening chronotype; TGCT cis rs1670533 1.000 rs676561 chr4:1083112 C/T cg20887711 chr4:1340912 KIAA1530 0.68 5.33 0.43 4.53e-7 Recombination rate (females); TGCT trans rs208520 0.802 rs208499 chr6:66932146 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.94 -9.93 -0.67 1.84e-17 Exhaled nitric oxide output; TGCT cis rs1344694 0.566 rs4672790 chr2:216892446 C/T cg12620499 chr2:216877984 MREG 0.84 9.85 0.66 2.9e-17 Alcohol dependence; TGCT cis rs10751667 1.000 rs6597965 chr11:964476 A/G cg06064525 chr11:970664 AP2A2 -0.33 -6.53 -0.51 1.54e-9 Alzheimer's disease (late onset); TGCT cis rs4285028 0.747 rs4048703 chr3:121374361 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.92 -7.33 -0.55 2.54e-11 Multiple sclerosis; TGCT cis rs10479542 0.896 rs4701131 chr5:178982446 A/G cg14820908 chr5:178986412 RUFY1 0.54 5.76 0.46 6.13e-8 Lung cancer; TGCT cis rs28595532 0.748 rs113336496 chr4:119336957 C/T cg21605333 chr4:119757512 SEC24D 0.85 5.43 0.44 2.84e-7 Cannabis dependence symptom count; TGCT cis rs28386778 0.591 rs2584619 chr17:61913215 T/A cg25654072 chr17:61904446 PSMC5;FTSJ3 0.55 5.03 0.41 1.68e-6 Prudent dietary pattern; TGCT cis rs7582180 0.613 rs12988464 chr2:100946285 A/G cg08017756 chr2:100939284 LONRF2 -0.3 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs2072499 0.966 rs6427307 chr1:156190083 A/G cg25208724 chr1:156163844 SLC25A44 1.08 15.41 0.81 1.37e-30 Testicular germ cell tumor; TGCT cis rs2115630 0.653 rs61394864 chr15:85170174 T/C cg11189052 chr15:85197271 WDR73 -0.74 -7.31 -0.55 2.89e-11 P wave terminal force; TGCT cis rs7666738 0.830 rs7680909 chr4:98934604 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs8177253 0.606 rs6787177 chr3:133450720 C/T cg11941060 chr3:133502564 NA -0.25 -5.13 -0.42 1.09e-6 Iron status biomarkers; TGCT trans rs9650657 0.530 rs6982381 chr8:10952500 A/T cg15556689 chr8:8085844 FLJ10661 -0.79 -7.6 -0.56 6.16e-12 Neuroticism; TGCT cis rs3785574 0.536 rs2854190 chr17:61960219 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.63 5.5 0.44 2.06e-7 Height; TGCT cis rs11249608 0.548 rs7732719 chr5:178463054 A/G cg01312482 chr5:178451176 ZNF879 -0.49 -4.83 -0.4 3.96e-6 Pubertal anthropometrics; TGCT cis rs4595586 0.545 rs6580894 chr12:39371951 A/G cg26963002 chr12:38532352 NA 0.54 4.53 0.38 1.36e-5 Morning vs. evening chronotype; TGCT cis rs1218582 0.510 rs2878411 chr1:154823545 C/T cg09359103 chr1:154839909 KCNN3 -0.52 -8.22 -0.59 2.36e-13 Prostate cancer; TGCT cis rs514406 0.929 rs554301 chr1:53321948 A/T cg25767906 chr1:53392781 SCP2 0.52 6.12 0.48 1.14e-8 Monocyte count; TGCT cis rs9467773 0.620 rs2504599 chr6:26641060 C/T cg05738196 chr6:26577821 NA 0.87 10.75 0.69 1.87e-19 Intelligence (multi-trait analysis); TGCT cis rs10791097 0.582 rs2282578 chr11:130735691 A/T cg14779329 chr11:130786720 SNX19 0.29 4.91 0.4 2.77e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT trans rs57221529 0.655 rs72704791 chr5:547896 A/G cg25482853 chr8:67687455 SGK3 1.19 9.29 0.64 6.72e-16 Lung disease severity in cystic fibrosis; TGCT cis rs4819052 0.851 rs7281263 chr21:46695606 T/C cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.67 0.39 7.7e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2739330 0.791 rs4822458 chr22:24265659 C/T cg12419862 chr22:24373484 LOC391322 -0.76 -8.11 -0.59 4.23e-13 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs477895 0.713 rs11607165 chr11:63963947 T/G cg23719950 chr11:63933701 MACROD1 -0.71 -5.87 -0.47 3.82e-8 Mean platelet volume; TGCT cis rs4663866 0.901 rs71426512 chr2:239187128 C/T cg17283117 chr2:239148619 HES6 0.99 4.58 0.38 1.12e-5 Irritable bowel syndrome; TGCT cis rs1127311 1.000 rs1127313 chr1:154556425 A/G cg17218026 chr1:154582156 ADAR -0.3 -7.51 -0.56 1e-11 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs7582180 0.629 rs11685250 chr2:100955137 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs7302981 1.000 rs7308356 chr12:50539611 A/G cg23855989 chr12:50355821 AQP5 -0.3 -4.5 -0.38 1.52e-5 Systolic blood pressure; TGCT cis rs17376456 0.542 rs10070350 chr5:93103753 C/G cg21475434 chr5:93447410 FAM172A 0.6 4.9 0.4 2.92e-6 Diabetic retinopathy; TGCT cis rs2841277 0.708 rs10083374 chr14:105402994 T/C cg19901468 chr14:105411992 AHNAK2 -0.28 -5.93 -0.47 2.77e-8 Rheumatoid arthritis; TGCT cis rs9926296 0.643 rs2159114 chr16:89831841 A/G cg04287289 chr16:89883240 FANCA 0.67 6.81 0.52 3.66e-10 Vitiligo; TGCT cis rs4851254 0.618 rs13033732 chr2:100644797 A/G cg22139774 chr2:100720529 AFF3 -0.45 -4.9 -0.4 2.94e-6 Intelligence (multi-trait analysis); TGCT cis rs68170813 0.559 rs77727587 chr7:106815754 C/G cg02696742 chr7:106810147 HBP1 -0.72 -6.28 -0.49 5.29e-9 Coronary artery disease; TGCT cis rs9929218 0.551 rs8051095 chr16:68722049 G/A cg01251360 chr16:68772225 CDH1 -0.25 -4.63 -0.38 9.19e-6 Colorectal cancer; TGCT cis rs9443645 0.901 rs1027813 chr6:79552118 G/T cg09184832 chr6:79620586 NA 0.47 5.23 0.43 6.98e-7 Intelligence (multi-trait analysis); TGCT cis rs2204008 0.837 rs11181857 chr12:38413255 C/G cg26384229 chr12:38710491 ALG10B 0.82 7.4 0.55 1.81e-11 Bladder cancer; TGCT cis rs6582630 0.519 rs11520262 chr12:38333051 A/G cg13010199 chr12:38710504 ALG10B 0.59 4.53 0.38 1.37e-5 Drug-induced liver injury (flucloxacillin); TGCT cis rs3771570 1.000 rs62193210 chr2:242323616 G/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs6089829 0.851 rs4809460 chr20:61661355 T/C cg03213289 chr20:61660250 NA 0.68 9.9 0.66 2.25e-17 Prostate cancer (SNP x SNP interaction); TGCT cis rs2204008 0.720 rs11180923 chr12:38255172 A/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.19e-11 Bladder cancer; TGCT cis rs4372836 0.504 rs6737027 chr2:29070805 A/G cg09522027 chr2:28974177 PPP1CB 0.57 5.66 0.45 9.84e-8 Body mass index; TGCT cis rs2739330 0.685 rs4822453 chr22:24254862 G/T cg23131131 chr22:24373011 LOC391322 -0.72 -7.73 -0.57 3.12e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs2836974 0.829 rs34227163 chr21:40551943 A/G cg06238570 chr21:40685208 BRWD1 0.72 6.58 0.51 1.16e-9 Cognitive function; TGCT cis rs7208859 0.623 rs426434 chr17:28925353 C/T cg13385521 chr17:29058706 SUZ12P 0.81 4.84 0.4 3.78e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs9486719 1.000 rs11153058 chr6:97012746 C/T cg06623918 chr6:96969491 KIAA0776 -0.99 -8.05 -0.59 5.65e-13 Migraine;Coronary artery disease; TGCT cis rs514406 0.861 rs7524476 chr1:53240212 C/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs3749237 0.964 rs7431078 chr3:49808190 G/A cg10152585 chr3:50297680 NA 0.5 4.65 0.39 8.38e-6 Resting heart rate; TGCT cis rs11098499 0.657 rs4463052 chr4:120313258 T/C cg09307838 chr4:120376055 NA 0.65 6.39 0.5 3.02e-9 Corneal astigmatism; TGCT cis rs35883536 0.631 rs2783704 chr1:101040652 T/A cg06223162 chr1:101003688 GPR88 0.42 8.0 0.58 7.5e-13 Monocyte count; TGCT cis rs992157 0.835 rs6707559 chr2:219142773 C/T cg00012203 chr2:219082015 ARPC2 0.8 7.98 0.58 8.26e-13 Colorectal cancer; TGCT cis rs17108533 0.588 rs34799286 chr14:71301968 A/T cg23900759 chr14:71108106 TTC9 -1.14 -4.61 -0.38 9.92e-6 Response to antipsychotic treatment in schizophrenia (reasoning); TGCT cis rs2982552 0.844 rs3020346 chr6:152056771 C/T cg22157087 chr6:152012887 ESR1 -0.21 -5.38 -0.43 3.6e-7 Bone properties (heel); TGCT cis rs7904368 0.754 rs12246217 chr10:16853349 G/C cg14835575 chr10:16859367 RSU1 0.72 7.72 0.57 3.43e-12 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs9902453 0.817 rs2617880 chr17:28106118 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.77 -7.19 -0.54 5.37e-11 Coffee consumption (cups per day); TGCT cis rs9549367 0.713 rs4907598 chr13:113861385 C/T cg09473364 chr13:112927190 NA 0.31 4.77 0.39 5e-6 Platelet distribution width; TGCT cis rs10256972 0.567 rs2960850 chr7:1211649 A/G cg18765753 chr7:1198926 ZFAND2A -0.5 -5.58 -0.45 1.43e-7 Longevity;Endometriosis; TGCT cis rs10504229 1.000 rs112284078 chr8:58191640 A/G cg22535103 chr8:58192502 C8orf71 -0.41 -5.14 -0.42 1.03e-6 Developmental language disorder (linguistic errors); TGCT cis rs4455778 0.565 rs7809432 chr7:49014472 C/T cg26309511 chr7:48887640 NA -0.42 -5.34 -0.43 4.26e-7 Lung cancer in never smokers; TGCT cis rs9372498 0.536 rs62424195 chr6:118812108 T/A cg21191810 chr6:118973309 C6orf204 -0.35 -4.72 -0.39 6.2e-6 Diastolic blood pressure; TGCT cis rs7727544 0.507 rs9791170 chr5:131569627 A/G cg24060327 chr5:131705240 SLC22A5 -0.6 -6.31 -0.49 4.4e-9 Blood metabolite levels; TGCT trans rs1496653 0.602 rs77659073 chr3:23618632 G/A cg02770683 chr12:57597238 LRP1 0.37 6.68 0.51 7.38e-10 Type 2 diabetes; TGCT cis rs716804 0.654 rs7928170 chr11:10178845 T/C cg17061862 chr11:9590431 NA -0.37 -4.87 -0.4 3.37e-6 Neuroticism; TGCT cis rs10504229 0.679 rs72649109 chr8:58031274 A/T cg02725872 chr8:58115012 NA -0.39 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs9400467 0.537 rs12213248 chr6:111499394 G/C cg15721981 chr6:111408429 SLC16A10 0.71 4.6 0.38 1.04e-5 Blood metabolite levels;Amino acid levels; TGCT cis rs9611565 0.559 rs7290991 chr22:41964361 C/G cg06634786 chr22:41940651 POLR3H -0.88 -8.25 -0.6 1.98e-13 Vitiligo; TGCT cis rs10504229 0.815 rs55855654 chr8:58164299 T/G cg20607798 chr8:58055168 NA 0.49 4.52 0.38 1.43e-5 Developmental language disorder (linguistic errors); TGCT cis rs7568458 1.000 rs7568458 chr2:85788175 T/A cg02493740 chr2:85810744 VAMP5 -0.29 -5.16 -0.42 9.58e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs10089 0.953 rs3805615 chr5:127519049 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.85 8.27 0.6 1.8e-13 Ileal carcinoids; TGCT cis rs9831754 0.906 rs7611939 chr3:78392751 A/C cg06138941 chr3:78371609 NA -0.49 -5.4 -0.44 3.25e-7 Calcium levels; TGCT cis rs72781680 0.898 rs72786286 chr2:24074659 T/A cg08917208 chr2:24149416 ATAD2B 0.77 4.69 0.39 7.06e-6 Lymphocyte counts; TGCT cis rs4372836 0.504 rs12714249 chr2:29055916 G/A cg09522027 chr2:28974177 PPP1CB -0.55 -5.51 -0.44 1.97e-7 Body mass index; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg15242686 chr22:24348715 GSTTP1 0.41 5.5 0.44 2.07e-7 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7178572 0.633 rs4886877 chr15:77838535 C/G cg22256960 chr15:77711686 NA -0.79 -7.47 -0.56 1.26e-11 Type 2 diabetes; TGCT cis rs13188771 0.690 rs10040426 chr5:100896781 T/C cg10455971 chr5:101119566 NA 0.44 4.45 0.37 1.87e-5 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs9910055 0.718 rs2526022 chr17:42213216 C/T cg19774624 chr17:42201019 HDAC5 -0.83 -8.49 -0.61 5.19e-14 Total body bone mineral density; TGCT cis rs1046896 0.576 rs8067360 chr17:80694826 T/C cg00960700 chr17:80709150 TBCD 0.5 4.93 0.4 2.61e-6 Glycated hemoglobin levels; TGCT cis rs4786125 0.588 rs1473516 chr16:6923077 C/T cg03623568 chr16:6915990 A2BP1 -0.44 -6.44 -0.5 2.39e-9 Heart rate variability traits (SDNN); TGCT cis rs9818758 0.607 rs34343820 chr3:49309534 C/G cg00383909 chr3:49044727 WDR6 1.28 6.57 0.51 1.23e-9 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7666738 0.830 rs7697315 chr4:98938764 T/C cg17366294 chr4:99064904 C4orf37 0.72 7.39 0.55 1.87e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.788 rs4819051 chr21:46693128 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.24 0.55 4.17e-11 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs12497850 0.931 rs7431710 chr3:48935583 G/A cg05785598 chr3:49045655 WDR6 0.35 4.72 0.39 6.35e-6 Parkinson's disease; TGCT cis rs939574 1.000 rs2293078 chr2:220100683 C/G cg00496455 chr2:220118770 TUBA4A;TUBA4B 1.05 6.38 0.5 3.13e-9 Platelet distribution width; TGCT cis rs500492 0.542 rs416055 chr16:1074931 G/A cg01366354 chr16:1075121 NA 0.36 5.23 0.43 6.99e-7 Polycystic ovary syndrome; TGCT cis rs1153858 1.000 rs1145085 chr15:45657804 A/G cg14582100 chr15:45693742 SPATA5L1 0.48 5.69 0.46 8.56e-8 Homoarginine levels; TGCT cis rs9611565 0.649 rs5758344 chr22:41817685 G/A cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs6938 0.514 rs35556055 chr15:75253414 G/A cg13906792 chr15:75199810 C15orf17 -0.2 -4.46 -0.37 1.85e-5 Breast cancer; TGCT cis rs6586111 1.000 rs7071672 chr10:82375965 C/G cg03086067 chr10:82368399 SH2D4B -0.23 -4.54 -0.38 1.33e-5 Capecitabine sensitivity; TGCT trans rs2688608 0.592 rs10762559 chr10:75486453 G/C cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.42e-10 Inflammatory bowel disease; TGCT cis rs36051895 0.623 rs7859361 chr9:5237479 C/T cg02405213 chr9:5042618 JAK2 -0.68 -8.01 -0.58 7.18e-13 Pediatric autoimmune diseases; TGCT cis rs4654899 0.833 rs10916858 chr1:21086602 C/G cg01072550 chr1:21505969 NA -0.49 -7.89 -0.58 1.37e-12 Superior frontal gyrus grey matter volume; TGCT cis rs10992471 0.603 rs2094281 chr9:95290654 C/G cg13798575 chr9:95087839 CENPP;NOL8 0.56 5.28 0.43 5.49e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs10984561 0.881 rs73540220 chr9:122249904 C/T cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs5760092 0.755 rs915589 chr22:24261004 C/T cg04234412 chr22:24373322 LOC391322 0.93 8.57 0.61 3.38e-14 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2147959 0.739 rs11587839 chr1:228630979 C/T cg22700015 chr1:228743131 NA -0.57 -4.53 -0.38 1.35e-5 Adult asthma; TGCT cis rs9926296 0.562 rs4785725 chr16:89893243 A/G cg01719998 chr16:89642051 CPNE7 -0.44 -4.46 -0.37 1.81e-5 Vitiligo; TGCT cis rs2239547 0.522 rs6773040 chr3:52935428 C/A cg11645453 chr3:52864694 ITIH4 -0.37 -6.08 -0.48 1.37e-8 Schizophrenia; TGCT cis rs9902453 0.817 rs2729435 chr17:28121532 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 -0.75 -6.81 -0.52 3.65e-10 Coffee consumption (cups per day); TGCT cis rs11190604 1.000 rs1106565 chr10:102211613 T/C cg16342193 chr10:102329863 NA -0.4 -5.31 -0.43 4.85e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs9611565 0.879 rs2235845 chr22:41729294 T/G cg03806693 chr22:41940476 POLR3H -0.86 -9.19 -0.64 1.16e-15 Vitiligo; TGCT cis rs36093844 0.898 rs11234462 chr11:85596924 C/T cg25872744 chr11:85566296 CCDC83 -0.48 -4.71 -0.39 6.45e-6 IgG response to Plasmodium falciparum antigens (GLURP, MSP2 FC27, MSP2 3D7); TGCT cis rs1901167 0.908 rs1061442 chr5:40982620 G/T cg02441090 chr5:41871058 OXCT1 -0.29 -4.45 -0.37 1.92e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs9650657 0.537 rs4841457 chr8:10773511 T/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.44 -0.37 1.94e-5 Neuroticism; TGCT cis rs11623869 0.711 rs2403173 chr14:103909289 T/C cg26031613 chr14:104095156 KLC1 0.87 9.75 0.66 5.07e-17 Bone mineral density; TGCT cis rs11252926 0.502 rs7072510 chr10:455596 C/T cg18196295 chr10:418757 DIP2C 0.3 4.85 0.4 3.6e-6 Psychosis in Alzheimer's disease; TGCT cis rs13118159 0.573 rs7664763 chr4:1352305 A/G cg05025164 chr4:1340916 KIAA1530 0.8 6.92 0.53 2.16e-10 Longevity; TGCT cis rs11085466 1.000 rs75079001 chr19:21757375 A/G cg02997983 chr19:21646781 NA -0.64 -4.52 -0.38 1.43e-5 Colorectal or endometrial cancer; TGCT cis rs35146811 0.735 rs6948729 chr7:99787372 A/G cg04778012 chr7:99775508 STAG3;GPC2 0.35 4.93 0.41 2.55e-6 Coronary artery disease; TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg24846343 chr22:24311635 DDTL 0.24 6.29 0.49 4.88e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs611744 0.647 rs615126 chr8:109247619 C/T cg21045802 chr8:109455806 TTC35 0.72 7.28 0.55 3.32e-11 Dupuytren's disease; TGCT cis rs950169 0.580 rs11634320 chr15:85172183 A/C cg11189052 chr15:85197271 WDR73 -0.73 -6.01 -0.47 1.96e-8 Schizophrenia; TGCT cis rs6969780 0.630 rs3735530 chr7:27189982 C/T cg17457637 chr7:27170717 HOXA4 -0.44 -4.81 -0.4 4.29e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs1008375 0.932 rs13109475 chr4:17677565 C/G cg18681998 chr4:17616180 MED28 -0.86 -8.49 -0.61 5.19e-14 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs8072100 0.840 rs2136751 chr17:45456093 A/G cg08085267 chr17:45401833 C17orf57 -0.46 -5.08 -0.42 1.33e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs72615157 0.634 rs79986079 chr7:99802044 C/T cg18515655 chr7:100026757 MEPCE;ZCWPW1 -0.6 -5.03 -0.41 1.68e-6 Lung function (FEV1/FVC); TGCT cis rs6951245 0.938 rs117729148 chr7:1108531 G/A cg27454412 chr7:1067447 C7orf50 0.6 4.7 0.39 6.76e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs2115630 0.967 rs11073702 chr15:85310071 G/A cg12501888 chr15:85177176 SCAND2 -0.48 -4.49 -0.37 1.6e-5 P wave terminal force; TGCT cis rs8031584 0.723 rs11632229 chr15:31179534 A/G cg08704250 chr15:31115839 NA 0.44 6.28 0.49 5.29e-9 Huntington's disease progression; TGCT cis rs9814567 1.000 rs1917130 chr3:134313773 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 0.95 9.14 0.63 1.54e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs4819052 0.851 rs28501512 chr21:46676702 C/T cg02159808 chr21:46707872 POFUT2;LOC642852 0.58 4.61 0.38 9.85e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9985766 0.916 rs62339880 chr4:150989230 G/A cg05926478 chr4:151174724 DCLK2 -0.24 -4.64 -0.38 8.63e-6 Coronary artery disease;Myocardial infarction; TGCT cis rs9486715 1.000 rs11153085 chr6:97066355 A/T cg18709589 chr6:96969512 KIAA0776 -0.77 -7.12 -0.54 7.74e-11 Headache; TGCT cis rs858239 0.601 rs73272053 chr7:23155525 A/G cg05602783 chr7:23145260 KLHL7 -0.71 -6.11 -0.48 1.2e-8 Cerebrospinal fluid biomarker levels; TGCT cis rs8013055 0.898 rs8014913 chr14:105977313 T/C cg23356831 chr14:105996513 TMEM121 0.41 6.33 0.49 4.01e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs7552404 1.000 rs4646961 chr1:76217169 G/A cg22875332 chr1:76189707 ACADM 0.76 9.2 0.64 1.1e-15 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs10114408 0.921 rs1890374 chr9:96661146 A/G cg13679303 chr9:96623674 NA -0.36 -4.63 -0.38 9.04e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs798766 0.779 rs55895920 chr4:1735930 C/T cg05874882 chr4:1763078 NA -0.35 -4.45 -0.37 1.86e-5 Bladder cancer;Urinary bladder cancer; TGCT cis rs9611565 0.729 rs202654 chr22:41841034 G/A cg17554472 chr22:41940697 POLR3H 0.46 5.0 0.41 1.89e-6 Vitiligo; TGCT cis rs7617773 0.780 rs34630841 chr3:48343261 G/A cg11946769 chr3:48343235 NME6 0.82 7.09 0.54 9.1e-11 Coronary artery disease; TGCT cis rs11642862 1.000 rs111954099 chr16:30789623 A/G cg02466173 chr16:30829666 NA -0.36 -4.45 -0.37 1.91e-5 Tonsillectomy; TGCT cis rs7829975 0.533 rs13274028 chr8:8729193 A/C cg08975724 chr8:8085496 FLJ10661 0.51 4.58 0.38 1.13e-5 Mood instability; TGCT cis rs875971 0.789 rs7808013 chr7:66071196 A/G cg11764359 chr7:65958608 NA -0.54 -4.9 -0.4 2.89e-6 Aortic root size; TGCT cis rs10875595 0.836 rs6868387 chr5:140660814 G/A cg20560182 chr5:140700478 TAF7 -0.66 -5.06 -0.41 1.49e-6 Pulmonary function decline; TGCT cis rs9611565 0.559 rs5758412 chr22:42080803 T/A cg13695892 chr22:41940480 POLR3H 0.89 8.6 0.61 2.92e-14 Vitiligo; TGCT cis rs12519773 0.597 rs4342312 chr5:92477890 C/A cg18783429 chr5:92414398 NA 0.31 4.66 0.39 7.94e-6 Migraine; TGCT cis rs4555082 0.834 rs2735825 chr14:105710900 G/A cg01266790 chr14:105781312 PACS2 0.55 4.49 0.37 1.58e-5 Mean platelet volume;Platelet distribution width; TGCT cis rs9303401 0.659 rs66514313 chr17:56714057 C/T cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs4644046 0.545 rs2397048 chr6:51430852 A/G cg14391730 chr6:52021665 NA 0.31 4.46 0.37 1.8e-5 Coronary artery disease; TGCT cis rs617219 0.698 rs7379187 chr5:78521354 T/C cg05890484 chr5:78407552 BHMT 0.36 5.01 0.41 1.84e-6 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6424115 0.830 rs2502994 chr1:24199363 T/C cg15997130 chr1:24165203 NA 0.86 9.44 0.65 2.86e-16 Immature fraction of reticulocytes; TGCT cis rs2227564 0.620 rs7098573 chr10:75580014 G/A cg04320760 chr10:75533139 FUT11 -0.32 -4.51 -0.38 1.49e-5 Crohn's disease;Inflammatory bowel disease; TGCT cis rs12497850 0.931 rs7621015 chr3:49016056 A/G cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.98e-6 Parkinson's disease; TGCT trans rs797680 0.856 rs10874764 chr1:93661342 C/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.82 -0.52 3.53e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT trans rs797680 0.856 rs6685271 chr1:93634590 C/A cg27528825 chr2:159282178 CCDC148 -0.35 -6.78 -0.52 4.27e-10 Eosinophil percentage of white cells;Sum eosinophil basophil counts; TGCT cis rs4853012 0.838 rs4452177 chr2:74345206 A/G cg20891558 chr2:74357851 NA 0.62 9.13 0.63 1.62e-15 Gestational age at birth (maternal effect); TGCT cis rs7119 0.700 rs4886883 chr15:77888924 C/T cg27398640 chr15:77910606 LINGO1 -0.31 -6.65 -0.51 8.37e-10 Type 2 diabetes; TGCT cis rs858239 0.632 rs1985769 chr7:23122506 T/G cg05602783 chr7:23145260 KLHL7 -0.6 -5.02 -0.41 1.76e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs2688608 0.592 rs11000758 chr10:75493610 A/T cg19442545 chr10:75533431 FUT11 -0.37 -5.77 -0.46 5.89e-8 Inflammatory bowel disease; TGCT cis rs8037137 0.915 rs8026714 chr15:91522253 G/A cg23684204 chr15:91497937 RCCD1 0.39 4.57 0.38 1.17e-5 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs1008375 1.000 rs1974624 chr4:17650281 A/G cg16339924 chr4:17578868 LAP3 0.63 5.26 0.43 6.22e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2549003 1.000 rs9282761 chr5:131822224 T/C cg02551604 chr5:131831745 NA -0.9 -12.1 -0.74 9.75e-23 Asthma (sex interaction); TGCT cis rs3617 0.599 rs12487379 chr3:52895785 G/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.48 -4.73 -0.39 5.88e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs3772130 0.962 rs9812228 chr3:121495682 C/G cg01951420 chr3:121553821 IQCB1;EAF2 0.52 4.72 0.39 6.25e-6 Cognitive performance; TGCT cis rs9381040 0.631 rs13216201 chr6:41162060 G/T cg03526776 chr6:41159608 TREML2 0.29 5.59 0.45 1.37e-7 Alzheimer's disease (late onset); TGCT cis rs1008375 0.966 rs2191504 chr4:17675592 C/G cg18681998 chr4:17616180 MED28 0.9 10.33 0.68 1.96e-18 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9357506 0.967 rs6911055 chr6:46307400 G/A cg21115430 chr6:46460003 NA -0.26 -5.17 -0.42 9.2e-7 Body mass index; TGCT cis rs587847 0.558 rs643132 chr15:37668511 G/A cg16890051 chr15:37175029 LOC145845 -0.38 -4.49 -0.37 1.6e-5 Intraocular pressure; TGCT cis rs2857078 0.745 rs4793085 chr17:42320732 A/C cg19774624 chr17:42201019 HDAC5 0.71 7.27 0.55 3.55e-11 Red cell distribution width;Reticulocyte count; TGCT cis rs6988636 0.536 rs16898043 chr8:124155886 A/G cg27053337 chr8:124217698 FAM83A 0.74 5.57 0.45 1.51e-7 Urinary uromodulin levels; TGCT cis rs9341808 0.718 rs10943699 chr6:80940541 G/A cg08355045 chr6:80787529 NA 0.29 5.16 0.42 9.42e-7 Sitting height ratio; TGCT cis rs2404602 0.692 rs1838048 chr15:76931679 A/G cg22467129 chr15:76604101 ETFA -0.45 -5.11 -0.42 1.18e-6 Blood metabolite levels; TGCT cis rs4654899 0.965 rs61781115 chr1:21322860 C/T cg01072550 chr1:21505969 NA -0.5 -7.94 -0.58 1.04e-12 Superior frontal gyrus grey matter volume; TGCT cis rs6547741 1.000 rs1972669 chr2:27767107 T/G cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs2204008 0.840 rs7957966 chr12:37953629 A/G cg26384229 chr12:38710491 ALG10B -0.7 -6.12 -0.48 1.11e-8 Bladder cancer; TGCT trans rs7819412 0.775 rs4545055 chr8:10935366 T/C cg06636001 chr8:8085503 FLJ10661 -0.77 -7.07 -0.54 1.01e-10 Triglycerides; TGCT cis rs295140 0.803 rs4516415 chr2:201129608 C/G cg04283868 chr2:201171347 SPATS2L 0.52 5.2 0.42 8.14e-7 QT interval; TGCT cis rs55883249 1.000 rs62119392 chr2:9714033 G/C cg23886495 chr2:9695866 ADAM17 0.83 4.99 0.41 2.02e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs13064411 0.696 rs6768979 chr3:113204149 G/A cg18753928 chr3:113234510 CCDC52 -0.7 -5.75 -0.46 6.6e-8 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs514406 0.861 rs562182 chr1:53270010 C/T cg08736216 chr1:53307985 ZYG11A -0.25 -4.71 -0.39 6.53e-6 Monocyte count; TGCT cis rs933688 1.000 rs1035477 chr5:90743325 T/C cg12630606 chr5:90679528 LOC100129716;ARRDC3 1.04 8.8 0.62 9.68e-15 Smoking behavior; TGCT cis rs7552404 0.656 rs11161792 chr1:76336746 C/T cg10523679 chr1:76189770 ACADM 0.69 6.19 0.49 8e-9 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs2880765 0.835 rs7169632 chr15:86044667 T/G cg13263323 chr15:86062960 AKAP13 -0.23 -4.82 -0.4 4.1e-6 Coronary artery disease; TGCT cis rs7584330 1.000 rs7584330 chr2:238387228 A/G cg08992911 chr2:238395768 MLPH 0.67 5.36 0.43 3.89e-7 Prostate cancer; TGCT cis rs62244186 0.627 rs12386385 chr3:44457540 A/G cg10263370 chr3:44754102 ZNF502 -0.38 -4.47 -0.37 1.75e-5 Depressive symptoms; TGCT cis rs7553864 0.614 rs1886634 chr1:87614821 C/T cg17420885 chr1:87600446 LOC339524 0.37 4.92 0.4 2.72e-6 Smoking behavior; TGCT cis rs3096299 0.504 rs4785574 chr16:89568875 A/G cg02187348 chr16:89574699 SPG7 0.55 5.7 0.46 8.45e-8 Multiple myeloma (IgH translocation); TGCT cis rs950169 0.922 rs11638445 chr15:85137694 C/A cg11189052 chr15:85197271 WDR73 0.76 6.33 0.49 4.13e-9 Schizophrenia; TGCT cis rs3617 0.573 rs4687680 chr3:52907372 G/A cg11645453 chr3:52864694 ITIH4 0.26 5.05 0.41 1.54e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs9549367 0.789 rs9549711 chr13:113900557 C/T cg00898013 chr13:113819073 PROZ -0.4 -5.03 -0.41 1.64e-6 Platelet distribution width; TGCT cis rs3771570 1.000 rs60604866 chr2:242352257 A/G cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.97e-10 Prostate cancer; TGCT cis rs11650494 0.831 rs73324348 chr17:47455752 G/A cg08112188 chr17:47440006 ZNF652 0.92 5.04 0.41 1.62e-6 Prostate cancer; TGCT cis rs933688 0.938 rs10063683 chr5:90714595 G/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 0.98 8.03 0.58 6.35e-13 Smoking behavior; TGCT cis rs6951245 1.000 rs80094748 chr7:1103958 G/A cg18402987 chr7:1209562 NA 0.78 6.64 0.51 8.96e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs3793683 0.520 rs12769959 chr10:134579026 A/C cg17054783 chr10:134559939 INPP5A 0.23 4.69 0.39 7.06e-6 Migraine; TGCT cis rs951366 0.764 rs708724 chr1:205743663 A/C cg26354017 chr1:205819088 PM20D1 0.57 7.08 0.54 9.44e-11 Menarche (age at onset); TGCT cis rs6121246 0.909 rs6060960 chr20:30394517 G/T cg18721089 chr20:30220636 NA 0.41 4.65 0.39 8.34e-6 Mean corpuscular hemoglobin; TGCT trans rs6089829 0.962 rs11086151 chr20:61664644 C/T cg13615516 chr5:77269221 NA 0.67 8.36 0.6 1.09e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs35934224 0.783 rs7288061 chr22:19864239 C/T cg11182965 chr22:19864308 TXNRD2 -0.38 -5.2 -0.42 7.82e-7 Glaucoma (primary open-angle); TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg26668828 chr6:292823 DUSP22 -0.84 -8.7 -0.62 1.71e-14 Menopause (age at onset); TGCT cis rs4862750 0.914 rs6814259 chr4:187872337 T/C cg10295955 chr4:187884368 NA -0.93 -12.52 -0.75 9.29e-24 Lobe attachment (rater-scored or self-reported); TGCT cis rs514406 0.505 rs269290 chr1:53167027 A/T cg16325326 chr1:53192061 ZYG11B 0.85 11.53 0.72 2.38e-21 Monocyte count; TGCT cis rs644799 0.763 rs2950521 chr11:95536870 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.89 10.57 0.69 5.17e-19 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs727563 0.555 rs5751136 chr22:42075581 T/A cg06481639 chr22:41940642 POLR3H 0.72 6.33 0.49 4e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9486715 0.838 rs9486275 chr6:96901187 C/T cg18709589 chr6:96969512 KIAA0776 0.79 7.77 0.57 2.5e-12 Headache; TGCT cis rs2204008 0.837 rs11612125 chr12:38213212 C/T cg13010199 chr12:38710504 ALG10B 0.62 4.96 0.41 2.32e-6 Bladder cancer; TGCT cis rs55794721 0.509 rs2375313 chr1:25748235 G/A cg00786635 chr1:25594202 NA 0.6 6.27 0.49 5.44e-9 Plateletcrit;Mean corpuscular volume; TGCT cis rs736408 0.527 rs2336147 chr3:52626443 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.6 -6.01 -0.47 1.96e-8 Bipolar disorder; TGCT cis rs9911578 0.967 rs1267542 chr17:56654690 T/C cg05425664 chr17:57184151 TRIM37 0.63 6.22 0.49 6.92e-9 Intelligence (multi-trait analysis); TGCT cis rs17767294 0.708 rs72846788 chr6:28130843 A/G cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT cis rs2688608 0.933 rs2633307 chr10:75653881 G/A cg04320760 chr10:75533139 FUT11 -0.29 -4.55 -0.38 1.27e-5 Inflammatory bowel disease; TGCT cis rs17270561 0.887 rs9358870 chr6:25719210 T/C cg17042849 chr6:26104293 HIST1H4C -0.69 -4.63 -0.38 8.93e-6 Iron status biomarkers; TGCT cis rs926938 0.584 rs1299780 chr1:115366014 G/A cg12756093 chr1:115239321 AMPD1 0.42 6.12 0.48 1.12e-8 Autism; TGCT cis rs1801251 0.963 rs35362030 chr2:233612845 A/G cg25237894 chr2:233734115 C2orf82 0.32 5.68 0.45 8.93e-8 Coronary artery disease; TGCT cis rs2204008 0.837 rs11168504 chr12:37964922 G/T cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs4862750 0.872 rs6811569 chr4:187897988 A/G cg22105103 chr4:187893119 NA -0.33 -4.45 -0.37 1.86e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs10461617 0.541 rs832575 chr5:56161787 C/T cg24531977 chr5:56204891 C5orf35 -0.71 -5.22 -0.42 7.41e-7 Type 2 diabetes; TGCT cis rs4642101 0.534 rs13316229 chr3:12807371 C/T cg04715183 chr3:11886989 C3orf31 -0.17 -4.44 -0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs66573146 0.831 rs56320732 chr4:6974319 G/A cg05069807 chr4:6945702 TBC1D14 0.32 5.01 0.41 1.83e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs7568458 0.636 rs11126995 chr2:85792408 A/T cg02493740 chr2:85810744 VAMP5 -0.31 -6.04 -0.48 1.69e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6671200 0.920 rs259350 chr1:95724831 G/C cg20701556 chr1:95698924 RWDD3 -0.67 -5.63 -0.45 1.13e-7 Stearic acid (18:0) levels; TGCT cis rs6061231 0.624 rs8668 chr20:60964064 C/T cg22633769 chr20:60982531 CABLES2 -0.55 -4.53 -0.38 1.4e-5 Colorectal cancer; TGCT cis rs611744 0.583 rs1448148 chr8:109333074 T/A cg18478394 chr8:109455254 TTC35 0.44 4.5 0.37 1.54e-5 Dupuytren's disease; TGCT cis rs7666738 0.822 rs11097599 chr4:98959562 T/A cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs56104184 0.775 rs17272700 chr19:49391770 G/A cg17863274 chr19:49399704 TULP2 -0.54 -7.43 -0.55 1.58e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs12681287 0.752 rs12679266 chr8:87258833 T/C cg27223183 chr8:87520930 FAM82B -0.82 -5.83 -0.46 4.5e-8 Caudate activity during reward; TGCT cis rs7582180 0.764 rs11686293 chr2:100922830 C/T cg14675211 chr2:100938903 LONRF2 0.49 4.8 0.4 4.49e-6 Intelligence (multi-trait analysis); TGCT cis rs9902453 0.619 rs1038088 chr17:28074563 T/G cg26525008 chr17:28256777 EFCAB5;SSH2 -0.8 -7.97 -0.58 8.91e-13 Coffee consumption (cups per day); TGCT cis rs7914558 0.966 rs3902934 chr10:104746649 A/G cg15744005 chr10:104629667 AS3MT -0.4 -4.91 -0.4 2.83e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs72627509 0.680 rs3733309 chr4:57857188 A/G cg26694713 chr4:57773883 REST 0.62 4.66 0.39 8.01e-6 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs13191362 0.507 rs2803083 chr6:163111199 A/C cg06582575 chr6:163149167 PACRG;PARK2 0.58 5.4 0.44 3.23e-7 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs10431058 0.684 rs539814 chr11:107466778 G/T cg18204760 chr11:107461044 ELMOD1;LOC643923 0.59 5.04 0.41 1.6e-6 Common traits (Other); TGCT cis rs858239 0.601 rs4140959 chr7:23170776 C/T cg05602783 chr7:23145260 KLHL7 -0.63 -5.28 -0.43 5.64e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs3820068 0.580 rs12760698 chr1:16009814 G/A cg05660106 chr1:15850417 CASP9 0.65 5.98 0.47 2.2e-8 Systolic blood pressure; TGCT cis rs7833790 0.685 rs13255262 chr8:82728024 T/G cg17211192 chr8:82754475 SNX16 -0.95 -8.83 -0.62 8.45e-15 Diastolic blood pressure; TGCT cis rs208520 0.690 rs207082 chr6:66773796 G/A cg07460842 chr6:66804631 NA -0.95 -10.19 -0.67 4.44e-18 Exhaled nitric oxide output; TGCT cis rs1552244 0.935 rs35586456 chr3:10116938 A/G cg00149659 chr3:10157352 C3orf10 0.93 6.0 0.47 2.05e-8 Alzheimer's disease; TGCT cis rs4746818 1.000 rs6480385 chr10:70904785 A/T cg04149295 chr10:70884716 VPS26A 0.78 5.37 0.43 3.68e-7 Left atrial antero-posterior diameter; TGCT cis rs1971762 0.545 rs10876466 chr12:53981426 G/C cg16917193 chr12:54089295 NA 0.89 9.11 0.63 1.74e-15 Height; TGCT cis rs6690583 0.623 rs2083284 chr1:85440023 C/T cg20280350 chr1:85513789 MCOLN3 -0.67 -4.5 -0.37 1.52e-5 Serum sulfate level; TGCT cis rs2836974 0.931 rs13047663 chr21:40708818 C/T cg17971929 chr21:40555470 PSMG1 0.92 7.81 0.57 2.06e-12 Cognitive function; TGCT cis rs7223966 0.960 rs2319990 chr17:61705397 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.59 4.93 0.4 2.59e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs801193 1.000 rs11773829 chr7:66141074 G/A cg18876405 chr7:65276391 NA -0.35 -5.2 -0.42 7.81e-7 Aortic root size; TGCT cis rs28595532 0.841 rs115851302 chr4:119776504 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs9399401 0.667 rs6903424 chr6:142699948 A/C cg03128060 chr6:142623767 GPR126 0.36 4.49 0.37 1.62e-5 Chronic obstructive pulmonary disease; TGCT cis rs727505 0.721 rs56269941 chr7:124768732 T/A cg23710748 chr7:124431027 NA -0.25 -4.44 -0.37 1.97e-5 Lewy body disease; TGCT cis rs524023 1.000 rs524023 chr11:64358265 C/T cg07733098 chr11:64478343 NRXN2 -0.31 -4.64 -0.38 8.56e-6 Urate levels in obese individuals; TGCT cis rs2839186 0.900 rs56840278 chr21:47708933 T/G cg13732083 chr21:47605072 C21orf56 0.35 4.69 0.39 7.17e-6 Testicular germ cell tumor; TGCT cis rs2303759 1.000 rs2303759 chr19:49869051 T/G cg22307029 chr19:49891270 CCDC155 0.56 5.28 0.43 5.56e-7 Multiple sclerosis; TGCT cis rs2836974 0.932 rs2836955 chr21:40619887 G/A cg11644478 chr21:40555479 PSMG1 0.96 9.96 0.67 1.58e-17 Cognitive function; TGCT cis rs7829975 0.514 rs2945873 chr8:8260445 C/T cg15556689 chr8:8085844 FLJ10661 0.75 6.77 0.52 4.56e-10 Mood instability; TGCT cis rs13326165 0.663 rs634382 chr3:52482851 A/G cg27565382 chr3:53032988 SFMBT1 -0.37 -4.87 -0.4 3.29e-6 HDL cholesterol;HDL cholesterol levels; TGCT cis rs9611565 0.659 rs9607815 chr22:41950671 A/T cg06481639 chr22:41940642 POLR3H -0.76 -6.97 -0.53 1.65e-10 Vitiligo; TGCT cis rs7772486 0.686 rs9399564 chr6:146078907 C/T cg05347473 chr6:146136440 FBXO30 -0.5 -4.76 -0.39 5.39e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7043114 0.525 rs4744134 chr9:95246833 A/G cg14631576 chr9:95140430 CENPP 0.29 4.64 0.38 8.83e-6 Height; TGCT cis rs9911578 0.967 rs4132925 chr17:56938016 C/G cg12560992 chr17:57184187 TRIM37 -0.76 -9.39 -0.64 3.77e-16 Intelligence (multi-trait analysis); TGCT cis rs4665809 1.000 rs4665819 chr2:26309073 A/G cg27170947 chr2:26402098 FAM59B -0.39 -4.46 -0.37 1.8e-5 Gut microbiome composition (summer); TGCT cis rs12541335 0.639 rs13257108 chr8:22165043 T/C cg02788857 chr8:22132959 PIWIL2 0.28 5.11 0.42 1.2e-6 Hypertriglyceridemia; TGCT cis rs4713118 0.868 rs9468220 chr6:27732976 A/G cg20933634 chr6:27740509 NA -0.34 -4.75 -0.39 5.58e-6 Parkinson's disease; TGCT cis rs3806843 0.801 rs801171 chr5:140115303 G/A cg19875535 chr5:140030758 IK -0.35 -5.94 -0.47 2.63e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7666738 0.830 rs11935078 chr4:99010476 T/A cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs2439831 0.850 rs2957637 chr15:43951118 C/A cg02155558 chr15:43621948 ADAL;LCMT2 0.93 6.72 0.52 5.83e-10 Lung cancer in ever smokers; TGCT cis rs4750440 0.637 rs2447010 chr10:14032115 T/C cg25464840 chr10:14372910 FRMD4A 0.33 4.46 0.37 1.82e-5 Adiponectin levels; TGCT cis rs2153535 0.541 rs9328477 chr6:8519109 T/C cg07606381 chr6:8435919 SLC35B3 0.54 5.01 0.41 1.86e-6 Motion sickness; TGCT cis rs9926296 0.585 rs1800337 chr16:89845194 A/G cg03388025 chr16:89894329 SPIRE2 0.53 9.45 0.65 2.66e-16 Vitiligo; TGCT cis rs67478160 0.634 rs2295140 chr14:104216293 C/T cg26031613 chr14:104095156 KLC1 -0.64 -6.49 -0.5 1.89e-9 Schizophrenia; TGCT cis rs4665809 0.556 rs4665314 chr2:26415912 T/C cg04944784 chr2:26401820 FAM59B -0.78 -6.56 -0.51 1.34e-9 Gut microbiome composition (summer); TGCT cis rs72627509 0.904 rs58408429 chr4:57769824 T/C cg26694713 chr4:57773883 REST 0.72 6.46 0.5 2.14e-9 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs6964587 0.967 rs10953065 chr7:91808915 A/G cg22709100 chr7:91322751 NA -0.28 -4.53 -0.38 1.34e-5 Breast cancer; TGCT cis rs1034435 0.755 rs5768679 chr22:48892847 T/G cg05992904 chr22:48892994 FAM19A5 -0.34 -4.65 -0.39 8.37e-6 Late-onset Alzheimer's disease; TGCT cis rs17376456 0.569 rs7732578 chr5:93410244 C/T cg25358565 chr5:93447407 FAM172A -0.62 -5.98 -0.47 2.22e-8 Diabetic retinopathy; TGCT cis rs2019137 0.560 rs4849179 chr2:113985170 C/T cg07772999 chr2:113993052 PAX8;LOC440839;LOC654433 0.51 5.4 0.44 3.28e-7 Lymphocyte counts; TGCT cis rs10883723 0.810 rs7094751 chr10:104274818 G/A cg11453585 chr10:104263688 ACTR1A;SUFU 0.83 8.75 0.62 1.33e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs992157 1.000 rs4674280 chr2:219141458 C/G cg00012203 chr2:219082015 ARPC2 -0.78 -8.14 -0.59 3.57e-13 Colorectal cancer; TGCT cis rs9902453 0.874 rs3936006 chr17:28257660 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.9 8.58 0.61 3.28e-14 Coffee consumption (cups per day); TGCT cis rs6683273 0.779 rs16824089 chr1:3230544 T/C cg17435683 chr1:3230609 PRDM16 -0.4 -4.53 -0.38 1.35e-5 QRS duration; TGCT cis rs6724607 1.000 rs4321393 chr2:191452899 G/T cg21644426 chr2:191273491 MFSD6 0.62 6.15 0.48 9.57e-9 Pulse pressure; TGCT trans rs1814175 0.817 rs7947286 chr11:49874657 C/T cg03929089 chr4:120376271 NA -0.72 -8.26 -0.6 1.84e-13 Height; TGCT cis rs2197308 0.765 rs11182964 chr12:37935052 C/T cg13010199 chr12:38710504 ALG10B 0.66 5.33 0.43 4.41e-7 Morning vs. evening chronotype; TGCT cis rs9457247 1.000 rs430293 chr6:167404958 A/G cg23791538 chr6:167370224 RNASET2 -0.49 -4.96 -0.41 2.26e-6 Crohn's disease; TGCT cis rs739496 0.843 rs657197 chr12:111965658 C/A cg10833066 chr12:111807467 FAM109A 0.37 5.59 0.45 1.4e-7 Platelet count; TGCT cis rs8014204 0.604 rs11625594 chr14:75389833 G/A cg06637938 chr14:75390232 RPS6KL1 0.94 10.46 0.68 9.58e-19 Caffeine consumption; TGCT cis rs10504229 0.953 rs78089850 chr8:58171557 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs7937612 0.965 rs12420378 chr11:120250699 A/G cg24566217 chr11:120254723 ARHGEF12 -0.28 -4.53 -0.38 1.37e-5 Intraocular pressure; TGCT cis rs250677 0.687 rs40149 chr5:148444275 A/T cg23229984 chr5:148520753 ABLIM3 0.21 4.99 0.41 1.98e-6 Breast cancer; TGCT trans rs2727020 0.729 rs4315497 chr11:49214499 G/A cg03929089 chr4:120376271 NA 0.71 7.91 0.58 1.2e-12 Coronary artery disease; TGCT cis rs9467773 1.000 rs4871 chr6:26545632 G/A cg15659132 chr6:26577336 NA 0.86 11.89 0.73 3.14e-22 Intelligence (multi-trait analysis); TGCT cis rs10504229 1.000 rs57378064 chr8:58169844 C/G cg22535103 chr8:58192502 C8orf71 -0.37 -4.73 -0.39 6.08e-6 Developmental language disorder (linguistic errors); TGCT cis rs7726839 0.540 rs7434 chr5:660804 A/G cg16035780 chr5:759353 NA -0.43 -4.44 -0.37 1.93e-5 Obesity-related traits; TGCT cis rs3125734 0.633 rs1835862 chr10:64056068 G/A cg09941381 chr10:64027924 RTKN2 -0.34 -5.04 -0.41 1.62e-6 Rheumatoid arthritis; TGCT cis rs11734570 0.581 rs79354477 chr4:38597448 C/T cg18361445 chr4:38666374 KLF3;FLJ13197 0.69 5.66 0.45 9.9e-8 Inflammatory bowel disease;Crohn's disease; TGCT cis rs7772486 0.875 rs10457795 chr6:146415665 A/G cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs12135062 0.851 rs2651925 chr1:3101863 C/G cg21609526 chr1:3105151 PRDM16 0.4 6.59 0.51 1.15e-9 Migraine; TGCT cis rs3096299 0.503 rs4785677 chr16:89555101 A/G cg02187348 chr16:89574699 SPG7 0.57 5.93 0.47 2.75e-8 Multiple myeloma (IgH translocation); TGCT cis rs28595532 0.920 rs55806110 chr4:119742583 A/G cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT trans rs17685 0.593 rs56265719 chr7:75796269 C/T cg19862616 chr7:65841803 NCRNA00174 0.52 9.04 0.63 2.61e-15 Coffee consumption;Coffee consumption (cups per day); TGCT cis rs7223966 1.000 rs7220821 chr17:61704147 G/A cg23090583 chr17:61904693 PSMC5;FTSJ3 0.61 5.17 0.42 9.12e-7 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs3935685 0.874 rs28406214 chr15:77996537 G/A cg03457338 chr15:78040120 NA -0.22 -5.8 -0.46 5.1e-8 Intelligence (multi-trait analysis); TGCT cis rs2050392 0.517 rs589980 chr10:30756385 T/A cg18806716 chr10:30721971 MAP3K8 -0.46 -5.43 -0.44 2.79e-7 Inflammatory bowel disease; TGCT cis rs951366 0.617 rs708727 chr1:205767885 G/A cg24503407 chr1:205819492 PM20D1 0.71 11.34 0.71 6.82e-21 Menarche (age at onset); TGCT cis rs75686122 0.892 rs76082564 chr8:104536649 T/C cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs4808199 0.948 rs968525 chr19:19459215 C/T cg02546618 chr19:19431379 KIAA0892;SF4 0.67 5.04 0.41 1.58e-6 Nonalcoholic fatty liver disease; TGCT cis rs1949733 0.523 rs16842563 chr4:8545146 C/T cg13073564 chr4:8508604 NA 0.48 4.99 0.41 2.02e-6 Response to antineoplastic agents; TGCT cis rs3733585 0.762 rs6449217 chr4:10009151 T/A cg00071950 chr4:10020882 SLC2A9 0.64 7.22 0.54 4.5e-11 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs1577917 1.000 rs1857964 chr6:86635994 A/T cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.67 -5.54 -0.45 1.73e-7 Response to antipsychotic treatment; TGCT cis rs2742417 1.000 rs1877932 chr3:45753539 A/G cg04837898 chr3:45731254 SACM1L -0.55 -5.72 -0.46 7.45e-8 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs3809566 0.963 rs12148057 chr15:63331509 A/T cg08198488 chr15:63333792 TPM1 -0.35 -5.23 -0.43 7e-7 Platelet count; TGCT cis rs6684514 1.000 rs59468948 chr1:156288058 A/T cg20302342 chr1:156215951 PAQR6 0.35 4.74 0.39 5.77e-6 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs992157 0.731 rs1399132 chr2:219159770 G/A cg00012203 chr2:219082015 ARPC2 0.78 7.72 0.57 3.38e-12 Colorectal cancer; TGCT cis rs12762955 0.528 rs10903358 chr10:1102386 G/A cg18964960 chr10:1102726 WDR37 0.74 5.36 0.43 3.87e-7 Response to angiotensin II receptor blocker therapy; TGCT cis rs736408 0.608 rs6445534 chr3:52743384 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Bipolar disorder; TGCT cis rs8056742 0.642 rs11649265 chr16:85050735 G/T cg00229868 chr16:85520891 NA -0.4 -4.88 -0.4 3.18e-6 Amyotrophic lateral sclerosis; TGCT cis rs6684514 1.000 rs10908496 chr1:156264000 G/A cg20302342 chr1:156215951 PAQR6 0.34 4.6 0.38 1.01e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs6089829 0.888 rs4809268 chr20:61675249 C/G cg02380750 chr20:61661411 NA 0.35 5.68 0.45 9.19e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs2997447 0.655 rs12059101 chr1:26384013 A/G cg19759804 chr1:25889155 LDLRAP1 0.33 4.55 0.38 1.25e-5 QRS complex (12-leadsum); TGCT cis rs7804356 0.651 rs17372780 chr7:26804018 C/G cg03456212 chr7:26904342 SKAP2 0.54 4.6 0.38 1.04e-5 Type 1 diabetes; TGCT cis rs9467711 0.606 rs9358938 chr6:26387546 C/T cg16898833 chr6:26189333 HIST1H4D 1.14 5.41 0.44 3.15e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9527 0.590 rs7910900 chr10:104829898 C/T cg15744005 chr10:104629667 AS3MT -0.42 -4.87 -0.4 3.29e-6 Arsenic metabolism; TGCT cis rs8070463 0.520 rs11652969 chr17:45817367 G/A cg06532163 chr17:45867833 NA 0.26 4.5 0.37 1.52e-5 Multiple sclerosis;Ankylosing spondylitis; TGCT cis rs11644362 0.966 rs35678048 chr16:12989235 A/G cg06890432 chr16:12997467 SHISA9 -0.62 -6.61 -0.51 1.05e-9 Positive affect;Subjective well-being; TGCT cis rs12887734 0.524 rs12888002 chr14:104238647 T/C cg26031613 chr14:104095156 KLC1 -0.72 -6.25 -0.49 6.02e-9 Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs595982 0.527 rs73061659 chr19:49373556 G/A cg17863274 chr19:49399704 TULP2 -0.47 -6.81 -0.52 3.78e-10 Red cell distribution width; TGCT cis rs896854 0.631 rs10097617 chr8:95961626 T/C cg23172400 chr8:95962367 TP53INP1 -0.4 -6.79 -0.52 4.23e-10 Type 2 diabetes; TGCT cis rs9486719 1.000 rs2472895 chr6:96870387 A/T cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs7829975 0.514 rs2976926 chr8:8261624 T/C cg08975724 chr8:8085496 FLJ10661 0.58 5.13 0.42 1.09e-6 Mood instability; TGCT cis rs7539409 0.651 rs10747407 chr1:84314754 G/A cg10977910 chr1:84465055 TTLL7 0.88 5.62 0.45 1.19e-7 Alzheimer's disease; TGCT cis rs6430585 0.583 rs4988145 chr2:136632300 A/C cg07169764 chr2:136633963 MCM6 1.23 12.35 0.74 2.37e-23 Corneal structure; TGCT cis rs7772486 0.875 rs9403764 chr6:146360582 G/A cg23711669 chr6:146136114 FBXO30 0.89 10.0 0.67 1.25e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs7523273 0.568 rs11118668 chr1:208017915 A/G cg22525895 chr1:207977042 MIR29B2 0.43 6.03 0.48 1.78e-8 Schizophrenia; TGCT cis rs79349575 0.783 rs12601858 chr17:47017477 T/C cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs9467773 0.595 rs2451736 chr6:26620544 G/A cg11502198 chr6:26597334 ABT1 0.53 4.9 0.4 2.95e-6 Intelligence (multi-trait analysis); TGCT trans rs2688608 0.618 rs28553894 chr10:75489843 C/A cg13918328 chr10:52500089 ASAH2B 0.68 6.73 0.52 5.68e-10 Inflammatory bowel disease; TGCT cis rs4788570 0.697 rs4788443 chr16:71805160 G/A cg06353428 chr16:71660113 MARVELD3 1.55 11.33 0.71 7.48e-21 Intelligence (multi-trait analysis); TGCT cis rs1538970 0.816 rs3790583 chr1:45956828 C/G cg05343316 chr1:45956843 TESK2 0.81 6.64 0.51 8.93e-10 Platelet count; TGCT cis rs4788815 0.712 rs4788563 chr16:71879868 A/C cg06353428 chr16:71660113 MARVELD3 0.83 7.37 0.55 2.07e-11 Metabolite levels; TGCT cis rs10838634 1.000 rs7928445 chr11:46784697 A/C cg18332754 chr11:46939436 LRP4 0.84 4.54 0.38 1.29e-5 Schizophrenia; TGCT cis rs12142240 0.698 rs68083747 chr1:46807416 T/G cg00530320 chr1:46809349 NSUN4 0.29 5.88 0.47 3.63e-8 Menopause (age at onset); TGCT cis rs72781680 0.898 rs113027486 chr2:24098371 G/A cg08917208 chr2:24149416 ATAD2B 0.78 4.79 0.4 4.69e-6 Lymphocyte counts; TGCT cis rs7208859 0.623 rs3794796 chr17:29130880 G/C cg14008862 chr17:28927542 LRRC37B2 0.77 4.61 0.38 9.76e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs12286929 0.699 rs1048932 chr11:115044850 C/A cg04017736 chr11:115827165 NA 0.2 4.87 0.4 3.29e-6 BMI in non-smokers;BMI (adjusted for smoking behaviour);Body mass index;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs4642101 0.561 rs9812144 chr3:12805910 G/A cg05775895 chr3:12838266 CAND2 0.53 5.22 0.42 7.19e-7 QRS complex (12-leadsum); TGCT cis rs7208859 0.623 rs75136574 chr17:28934549 C/A cg14008862 chr17:28927542 LRRC37B2 0.88 5.32 0.43 4.75e-7 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs4319547 0.656 rs10744209 chr12:122931568 G/A cg05707623 chr12:122985044 ZCCHC8 -0.71 -5.49 -0.44 2.16e-7 Body mass index; TGCT cis rs11785400 0.963 rs9771845 chr8:143726577 C/G cg24634471 chr8:143751801 JRK 0.55 5.92 0.47 2.93e-8 Schizophrenia; TGCT cis rs868036 0.681 rs28376010 chr15:68063739 G/T cg05925327 chr15:68127851 NA -0.51 -4.82 -0.4 4.2e-6 Restless legs syndrome; TGCT cis rs3917265 0.602 rs997049 chr2:102782433 T/A cg17937070 chr2:102766322 NA -0.32 -4.48 -0.37 1.66e-5 Atopic dermatitis; TGCT cis rs1862618 0.853 rs1862619 chr5:56098256 T/A cg24549020 chr5:56110836 MAP3K1 0.66 5.79 0.46 5.56e-8 Initial pursuit acceleration; TGCT cis rs427394 0.664 rs274696 chr5:6732213 A/C cg10857441 chr5:6722123 POLS -0.29 -7.23 -0.54 4.25e-11 Menopause (age at onset); TGCT cis rs2729354 0.768 rs1001956 chr11:57266949 C/G cg24343310 chr11:57249947 NA 0.28 4.71 0.39 6.56e-6 Blood protein levels; TGCT cis rs4273100 0.646 rs1472932 chr17:19220666 C/T cg01534423 chr17:18965556 NA -0.76 -7.04 -0.53 1.19e-10 Schizophrenia; TGCT cis rs17376456 0.825 rs13361613 chr5:93272176 C/T cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs950169 0.840 rs72748702 chr15:84915246 A/G cg17173187 chr15:85201210 NMB 0.54 5.55 0.45 1.67e-7 Schizophrenia; TGCT cis rs986417 0.892 rs8012339 chr14:60797545 T/G cg27398547 chr14:60952738 C14orf39 -1.56 -6.75 -0.52 5.13e-10 Gut microbiota (bacterial taxa); TGCT cis rs208520 0.690 rs2208442 chr6:66867004 T/C cg07460842 chr6:66804631 NA -0.92 -9.58 -0.65 1.29e-16 Exhaled nitric oxide output; TGCT cis rs6813479 0.562 rs2634900 chr4:137733596 C/A cg04252851 chr4:137733453 NA -0.25 -4.48 -0.37 1.69e-5 Longevity; TGCT cis rs2455799 0.613 rs6789076 chr3:15807725 A/T cg16303742 chr3:15540471 COLQ 0.25 4.85 0.4 3.6e-6 Mean platelet volume; TGCT cis rs13118159 0.714 rs6843025 chr4:1334418 C/G cg19318889 chr4:1322082 MAEA 0.19 4.53 0.38 1.35e-5 Longevity; TGCT cis rs56104184 0.775 rs55737338 chr19:49403141 A/G cg15549821 chr19:49342101 PLEKHA4 -0.73 -9.15 -0.63 1.47e-15 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs2013441 1.000 rs4924808 chr17:20026548 C/T cg23224458 chr17:20280056 CCDC144C -0.37 -4.59 -0.38 1.06e-5 Obesity-related traits; TGCT cis rs2739330 0.753 rs4822452 chr22:24254363 C/T cg25703541 chr22:24373054 LOC391322 -0.81 -8.4 -0.6 8.79e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs986417 0.901 rs6573315 chr14:60996831 A/C cg27398547 chr14:60952738 C14orf39 1.41 9.14 0.63 1.53e-15 Gut microbiota (bacterial taxa); TGCT cis rs8135665 0.625 rs34385006 chr22:38450291 C/T cg13116946 chr22:38479732 SLC16A8 0.29 5.67 0.45 9.62e-8 Advanced age-related macular degeneration;Age-related macular degeneration; TGCT cis rs7582180 0.607 rs6725052 chr2:100935817 G/A cg14675211 chr2:100938903 LONRF2 0.51 4.95 0.41 2.32e-6 Intelligence (multi-trait analysis); TGCT cis rs35000415 0.745 rs117473643 chr7:128698186 G/C cg06242719 chr7:129414860 MIR183;MIR96 -0.34 -4.67 -0.39 7.58e-6 Systemic lupus erythematosus; TGCT cis rs9341808 0.690 rs2505932 chr6:80839252 G/T cg08355045 chr6:80787529 NA 0.32 5.38 0.43 3.6e-7 Sitting height ratio; TGCT cis rs2019137 0.936 rs3828188 chr2:113954247 G/A cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs2777491 0.957 rs316614 chr15:41746625 A/G cg18705301 chr15:41695430 NDUFAF1 -0.75 -11.07 -0.71 3.15e-20 Ulcerative colitis; TGCT cis rs35306767 0.714 rs12777800 chr10:1070361 G/A cg26597838 chr10:835615 NA 0.61 7.08 0.54 9.27e-11 Eosinophil percentage of granulocytes; TGCT cis rs713587 0.719 rs4665736 chr2:25187599 C/T cg15423357 chr2:25149977 NA -0.58 -5.9 -0.47 3.22e-8 Body mass index in non-asthmatics; TGCT cis rs877282 0.945 rs11253396 chr10:789754 C/T cg17470449 chr10:769945 NA 0.3 4.82 0.4 4.14e-6 Uric acid levels; TGCT cis rs763014 1.000 rs763014 chr16:675680 T/C cg00908189 chr16:619842 PIGQ 0.87 10.65 0.69 3.27e-19 Height; TGCT cis rs5769765 0.773 rs4075331 chr22:50302850 A/G cg15316289 chr22:50310904 ALG12;CRELD2 0.39 5.61 0.45 1.24e-7 Schizophrenia; TGCT cis rs2334880 0.678 rs12444714 chr16:71452606 C/T cg06353428 chr16:71660113 MARVELD3 -1.19 -7.9 -0.58 1.3e-12 Malaria; TGCT cis rs259282 0.652 rs2161458 chr19:33129038 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.6 5.82 0.46 4.63e-8 Schizophrenia; TGCT cis rs7772486 0.590 rs1890170 chr6:146071839 G/C cg23711669 chr6:146136114 FBXO30 -0.74 -6.63 -0.51 9.18e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs67460515 0.892 rs7647374 chr3:160975576 T/A cg03342759 chr3:160939853 NMD3 -0.49 -5.3 -0.43 5.16e-7 Parkinson's disease; TGCT cis rs1784581 0.928 rs1789995 chr6:162396518 C/T cg17173639 chr6:162384350 PARK2 -0.51 -9.75 -0.66 5.12e-17 Itch intensity from mosquito bite; TGCT cis rs57994353 0.667 rs34985258 chr9:139327154 C/T cg13741927 chr9:139327495 INPP5E -0.27 -6.26 -0.49 5.81e-9 Eosinophil counts;Cutaneous squamous cell carcinoma; TGCT cis rs1451375 1.000 rs10250513 chr7:50621488 T/G cg18232548 chr7:50535776 DDC 0.43 6.8 0.52 3.98e-10 Malaria; TGCT cis rs3020736 0.500 rs6519306 chr22:42501217 T/C cg05082376 chr22:42548792 NA 0.23 5.43 0.44 2.83e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs17401966 0.540 rs6682868 chr1:10454773 C/T cg19773385 chr1:10388646 KIF1B 0.21 5.12 0.42 1.12e-6 Hepatocellular carcinoma; TGCT cis rs739401 0.572 rs739400 chr11:3016520 G/A cg25174290 chr11:3078921 CARS 0.49 4.59 0.38 1.08e-5 Longevity; TGCT cis rs4862750 1.000 rs4862751 chr4:187904050 G/A cg03452623 chr4:187889614 NA -0.37 -5.7 -0.46 8.2e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs1334894 1.000 rs755658 chr6:35549670 A/G cg24281267 chr6:35479648 TULP1 0.43 4.47 0.37 1.78e-5 Coronary artery disease; TGCT cis rs317689 0.658 rs490872 chr12:69645864 A/G cg14784868 chr12:69753453 YEATS4 0.54 4.5 0.37 1.56e-5 Response to diuretic therapy; TGCT cis rs17376456 0.877 rs10050465 chr5:93349963 C/A cg21475434 chr5:93447410 FAM172A 0.6 4.74 0.39 5.71e-6 Diabetic retinopathy; TGCT cis rs1555895 0.521 rs1057303 chr10:853155 T/C cg02193355 chr10:851439 NA 0.24 5.33 0.43 4.45e-7 Survival in rectal cancer; TGCT cis rs1941023 0.503 rs2233238 chr11:60145441 G/C cg08716584 chr11:60157161 MS4A7 -0.34 -4.84 -0.4 3.81e-6 Congenital heart disease (maternal effect); TGCT cis rs12477438 1.000 rs12466388 chr2:99916538 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.8 -6.4 -0.5 2.91e-9 Chronic sinus infection; TGCT cis rs1008375 1.000 rs114490726 chr4:17680898 T/C cg16339924 chr4:17578868 LAP3 0.56 4.8 0.4 4.43e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs727505 1.000 rs10265763 chr7:124451514 G/A cg23710748 chr7:124431027 NA -0.27 -4.65 -0.39 8.35e-6 Lewy body disease; TGCT cis rs6500602 0.727 rs4786510 chr16:4571247 A/G cg14951292 chr16:4525986 HMOX2;NMRAL1 0.32 5.97 0.47 2.35e-8 Schizophrenia; TGCT cis rs4918072 0.917 rs61861158 chr10:105661686 A/G cg11005552 chr10:105648138 OBFC1 0.41 5.4 0.44 3.29e-7 Coronary artery disease; TGCT cis rs910316 0.967 rs11159121 chr14:75666029 A/T cg08847533 chr14:75593920 NEK9 -0.94 -10.27 -0.68 2.77e-18 Height; TGCT cis rs4953076 0.613 rs11124981 chr2:44462133 A/T cg00619915 chr2:44497795 NA -0.22 -4.99 -0.41 1.96e-6 Height; TGCT cis rs1150668 0.799 rs853684 chr6:28294550 T/C cg13525197 chr6:28411240 ZSCAN23 -0.47 -4.65 -0.39 8.37e-6 Pubertal anthropometrics; TGCT cis rs7714584 1.000 rs10061105 chr5:150255185 C/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs3796352 1.000 rs71617204 chr3:53042951 G/A cg15956490 chr3:53032818 SFMBT1 0.62 6.82 0.52 3.6e-10 Immune reponse to smallpox (secreted IL-2); TGCT cis rs11098499 0.863 rs3775844 chr4:120428033 G/A cg09307838 chr4:120376055 NA 0.68 6.45 0.5 2.28e-9 Corneal astigmatism; TGCT cis rs2885056 0.699 rs34275421 chr19:10644812 T/A cg04833646 chr19:10679720 CDKN2D 0.83 7.24 0.54 4.24e-11 Red cell distribution width; TGCT cis rs478304 0.654 rs1074155 chr11:65458197 C/T cg27068330 chr11:65405492 SIPA1 0.96 10.74 0.69 2.05e-19 Acne (severe); TGCT cis rs1862618 0.853 rs2432195 chr5:56120413 C/T cg20203395 chr5:56204925 C5orf35 -0.59 -5.12 -0.42 1.12e-6 Initial pursuit acceleration; TGCT cis rs7707921 0.522 rs9293290 chr5:81474225 A/T cg15871215 chr5:81402204 ATG10 -0.24 -4.59 -0.38 1.08e-5 Breast cancer; TGCT cis rs7666738 0.618 rs10856932 chr4:98819992 C/T cg18180107 chr4:99064573 C4orf37 0.55 5.25 0.43 6.31e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1451375 0.657 rs7802148 chr7:50648284 T/C cg18232548 chr7:50535776 DDC 0.44 6.72 0.52 5.81e-10 Malaria; TGCT cis rs2204008 0.806 rs35534445 chr12:38279093 C/T cg26384229 chr12:38710491 ALG10B 0.86 7.48 0.56 1.17e-11 Bladder cancer; TGCT cis rs28374715 0.562 rs8036686 chr15:41550333 C/T cg18705301 chr15:41695430 NDUFAF1 -0.66 -8.71 -0.62 1.61e-14 Ulcerative colitis; TGCT cis rs74233809 1.000 rs1060240 chr10:104883337 A/G cg05855489 chr10:104503620 C10orf26 0.82 4.44 0.37 1.97e-5 Birth weight; TGCT cis rs17741873 0.836 rs4746155 chr10:75661571 A/G cg07699608 chr10:75541558 CHCHD1 0.69 4.86 0.4 3.42e-6 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs2932538 0.961 rs4838960 chr1:113163632 G/T cg22162597 chr1:113214053 CAPZA1 -0.26 -5.82 -0.46 4.83e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs6582630 0.555 rs10880607 chr12:38508184 A/G cg13010199 chr12:38710504 ALG10B 0.64 5.15 0.42 9.97e-7 Drug-induced liver injury (flucloxacillin); TGCT cis rs4919694 0.611 rs77328741 chr10:105066314 T/C cg04362960 chr10:104952993 NT5C2 0.91 6.05 0.48 1.59e-8 Arsenic metabolism; TGCT cis rs909674 0.524 rs5750821 chr22:39825492 A/T cg01416388 chr22:39784598 NA -0.7 -6.92 -0.53 2.11e-10 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs10089 1.000 rs4836366 chr5:127482494 A/T cg19767477 chr5:127420684 SLC12A2 -0.43 -4.55 -0.38 1.27e-5 Ileal carcinoids; TGCT cis rs896854 0.654 rs13248607 chr8:95986637 T/G cg16049864 chr8:95962084 TP53INP1 -0.72 -10.2 -0.68 4.16e-18 Type 2 diabetes; TGCT cis rs9333029 0.722 rs7540241 chr1:47258219 A/T cg07352594 chr1:46664316 POMGNT1 -0.71 -4.51 -0.38 1.51e-5 Blood metabolite levels; TGCT cis rs11167764 0.945 rs891991 chr5:141484977 A/T cg02659431 chr5:141694439 SPRY4 -0.21 -4.54 -0.38 1.33e-5 Crohn's disease; TGCT cis rs12039431 0.748 rs6692773 chr1:38025407 G/A cg17933807 chr1:38061675 GNL2 -0.8 -7.83 -0.58 1.84e-12 Epithelial ovarian cancer; TGCT cis rs1371867 0.846 rs1660324 chr8:101281271 C/T cg06636551 chr8:101224915 SPAG1 -0.49 -6.83 -0.52 3.32e-10 Atrioventricular conduction; TGCT cis rs66573146 0.808 rs55942328 chr4:6990960 T/G cg05069807 chr4:6945702 TBC1D14 0.31 4.85 0.4 3.63e-6 Granulocyte percentage of myeloid white cells; TGCT cis rs2594714 0.538 rs895819 chr19:13947292 A/G cg18576835 chr19:13944261 NA -0.5 -7.12 -0.54 7.83e-11 Breast cancer; TGCT cis rs597539 0.690 rs647661 chr11:68625875 T/C cg21963583 chr11:68658836 MRPL21 0.39 6.3 0.49 4.78e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7666738 0.830 rs11931166 chr4:99054187 A/T cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs600550 0.963 rs4939329 chr11:60021507 C/A cg18570331 chr11:60101691 MS4A6E 0.52 4.48 0.37 1.67e-5 Lipoprotein-associated phospholipase A2 activity and mass; TGCT trans rs34421088 0.560 rs2245357 chr8:11399484 A/T cg15556689 chr8:8085844 FLJ10661 -0.74 -7.03 -0.53 1.23e-10 Neuroticism; TGCT cis rs60843830 0.661 rs55987018 chr2:106655 C/T cg25945732 chr2:264204 ACP1;SH3YL1 0.62 5.47 0.44 2.43e-7 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs1371867 0.846 rs1788194 chr8:101277916 T/C cg00191853 chr8:101177733 SPAG1 -0.22 -4.5 -0.37 1.53e-5 Atrioventricular conduction; TGCT cis rs735396 1.000 rs2464195 chr12:121435475 G/A cg02403541 chr12:121454288 C12orf43 0.66 6.42 0.5 2.59e-9 N-glycan levels; TGCT cis rs617219 0.726 rs2364596 chr5:78434291 C/T cg23987322 chr5:78407566 BHMT 0.34 4.48 0.37 1.66e-5 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs6542838 0.641 rs4851176 chr2:99534859 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.56 -5.32 -0.43 4.61e-7 Fear of minor pain; TGCT cis rs4631830 0.900 rs11006274 chr10:51540291 C/T cg10326726 chr10:51549505 MSMB 0.26 5.28 0.43 5.55e-7 Prostate-specific antigen levels; TGCT cis rs1371867 0.875 rs962452 chr8:101331369 G/A cg00191853 chr8:101177733 SPAG1 -0.23 -4.76 -0.39 5.2e-6 Atrioventricular conduction; TGCT cis rs4253772 0.591 rs12167567 chr22:46659942 G/C cg09491104 chr22:46646882 C22orf40 -0.67 -6.65 -0.51 8.56e-10 LDL cholesterol;Cholesterol, total; TGCT cis rs7027203 0.790 rs10123836 chr9:96584109 G/T cg14396892 chr9:96623032 NA -0.29 -6.22 -0.49 7.08e-9 DNA methylation (variation); TGCT cis rs8070128 0.534 rs2955350 chr17:17953548 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.79 -8.27 -0.6 1.76e-13 Total body bone mineral density; TGCT cis rs9611519 0.780 rs9611528 chr22:41648502 T/C cg13695892 chr22:41940480 POLR3H -0.64 -6.05 -0.48 1.59e-8 Neuroticism; TGCT cis rs67311347 1.000 rs13073003 chr3:40504326 C/T cg17264618 chr3:40429014 ENTPD3 -0.33 -4.85 -0.4 3.66e-6 Renal cell carcinoma; TGCT cis rs1538970 0.816 rs12029322 chr1:45970446 C/T cg05343316 chr1:45956843 TESK2 0.81 6.64 0.51 8.93e-10 Platelet count; TGCT cis rs6671200 1.000 rs71654419 chr1:95664497 C/G cg26537280 chr1:95699037 RWDD3 0.68 5.49 0.44 2.15e-7 Stearic acid (18:0) levels; TGCT cis rs2742417 1.000 rs2742379 chr3:45787835 G/A cg04837898 chr3:45731254 SACM1L -0.53 -5.52 -0.44 1.92e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs1799949 0.965 rs9897425 chr17:41430179 C/G cg05368731 chr17:41323189 NBR1 1.09 12.62 0.75 5.36e-24 Menopause (age at onset); TGCT cis rs523522 0.962 rs11065154 chr12:120971417 T/C cg27279351 chr12:120934652 DYNLL1 0.76 6.59 0.51 1.15e-9 High light scatter reticulocyte count; TGCT cis rs17376456 0.741 rs7718842 chr5:93480568 G/A cg25358565 chr5:93447407 FAM172A 0.97 8.27 0.6 1.76e-13 Diabetic retinopathy; TGCT cis rs1669338 0.588 rs55959448 chr3:3204000 C/T cg16797762 chr3:3221439 CRBN -0.91 -5.73 -0.46 7.34e-8 White matter integrity; TGCT cis rs6495122 0.644 rs11630087 chr15:75261673 G/T cg10253484 chr15:75165896 SCAMP2 -0.6 -5.51 -0.44 2.02e-7 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs9913156 0.793 rs8074545 chr17:4567337 C/G cg00122941 chr17:4613640 ARRB2 -0.89 -7.56 -0.56 7.65e-12 Lymphocyte counts; TGCT cis rs4595586 0.545 rs6580896 chr12:39372223 C/T cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs554111 0.656 rs4654900 chr1:21422021 G/C cg01072550 chr1:21505969 NA 0.36 5.46 0.44 2.51e-7 Facial morphology (factor 17, height of vermillion upper lip); TGCT cis rs7614311 0.636 rs73117066 chr3:63926236 A/G cg22134162 chr3:63841271 THOC7 -0.49 -6.18 -0.49 8.42e-9 Lung function (FVC);Lung function (FEV1); TGCT cis rs17125944 0.542 rs75723366 chr14:53256882 T/C cg00686598 chr14:53173677 PSMC6 1.08 6.32 0.49 4.37e-9 Alzheimer's disease (late onset); TGCT cis rs3774830 0.714 rs7688517 chr4:5466392 A/C cg26943120 chr4:5472116 STK32B 0.23 5.02 0.41 1.78e-6 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9611565 0.592 rs4822046 chr22:41987543 G/A cg06481639 chr22:41940642 POLR3H -0.75 -6.47 -0.5 2.1e-9 Vitiligo; TGCT cis rs769267 0.929 rs2905431 chr19:19482882 G/A cg20644253 chr19:19431407 KIAA0892;SF4 -0.67 -5.54 -0.45 1.72e-7 Tonsillectomy; TGCT cis rs6831352 0.879 rs1984362 chr4:100070973 G/A cg12011299 chr4:100065546 ADH4 -0.46 -5.22 -0.42 7.38e-7 Alcohol dependence; TGCT cis rs16866061 1.000 rs10498163 chr2:225434445 A/G cg12698349 chr2:225449008 CUL3 1.01 9.8 0.66 3.91e-17 Acute graft versus host disease in bone marrow transplantation (recipient effect); TGCT cis rs2486288 0.656 rs12904150 chr15:45547605 T/C cg26924012 chr15:45694286 SPATA5L1 -0.72 -7.46 -0.56 1.34e-11 Glomerular filtration rate; TGCT cis rs7568458 0.709 rs56819945 chr2:85755139 C/T cg02493740 chr2:85810744 VAMP5 -0.28 -5.37 -0.43 3.67e-7 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs2180341 0.960 rs6900074 chr6:127685893 A/G cg24812749 chr6:127587940 RNF146 0.93 7.28 0.55 3.34e-11 Breast cancer; TGCT cis rs864537 0.676 rs3108155 chr1:167422057 C/G cg22356347 chr1:167427500 CD247 -0.22 -5.47 -0.44 2.35e-7 Celiac disease or Rheumatoid arthritis;Celiac disease; TGCT cis rs9303401 0.614 rs35245220 chr17:56510305 G/A cg10487724 chr17:56770010 TEX14;RAD51C 0.68 6.66 0.51 8.09e-10 Cognitive test performance; TGCT cis rs6089584 0.816 rs4925336 chr20:60627180 A/G cg16423285 chr20:60520624 NA -0.69 -6.96 -0.53 1.73e-10 Body mass index; TGCT cis rs6809651 0.524 rs7622914 chr3:185790895 T/C cg00760338 chr3:185826511 ETV5 -0.71 -5.3 -0.43 5.05e-7 Body mass index in physically active individuals;Glomerular filtration rate (creatinine);Body mass index (joint analysis main effects and physical activity interaction);Body mass index;Body mass index in physically inactive individuals; TGCT cis rs17387100 1.000 rs17387100 chr4:15995125 A/G cg14577840 chr4:16257979 FLJ39653 0.47 4.51 0.38 1.5e-5 Suicide attempts in depression or bipolar disorder; TGCT cis rs7666738 0.724 rs28451676 chr4:98966990 C/T cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.48e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs13256369 0.802 rs11249887 chr8:8562184 T/C cg18904891 chr8:8559673 CLDN23 0.57 5.29 0.43 5.35e-7 Obesity-related traits; TGCT cis rs2153535 0.623 rs2327055 chr6:8443145 A/G cg07606381 chr6:8435919 SLC35B3 0.57 5.25 0.43 6.46e-7 Motion sickness; TGCT cis rs4746818 0.688 rs951718 chr10:70928044 A/G cg11621586 chr10:70884670 VPS26A 1.23 10.93 0.7 6.87e-20 Left atrial antero-posterior diameter; TGCT cis rs76878669 0.538 rs1785633 chr11:66107527 C/A cg18002602 chr11:66138449 SLC29A2 0.53 6.45 0.5 2.23e-9 Educational attainment (years of education); TGCT cis rs17741873 0.836 rs17631059 chr10:75625558 G/C cg07699608 chr10:75541558 CHCHD1 0.79 5.64 0.45 1.1e-7 Paclitaxel disposition in epithelial ovarian cancer; TGCT cis rs2832191 0.671 rs2832213 chr21:30512914 A/G cg24692254 chr21:30365293 RNF160 -0.6 -5.57 -0.45 1.51e-7 Dental caries; TGCT cis rs7582180 0.629 rs4850927 chr2:100969067 A/G cg08017756 chr2:100939284 LONRF2 -0.29 -4.73 -0.39 5.99e-6 Intelligence (multi-trait analysis); TGCT cis rs262150 0.536 rs73167296 chr7:158783129 C/T cg01219135 chr7:158766336 NA -0.44 -4.64 -0.38 8.89e-6 Facial morphology (factor 20); TGCT cis rs4727027 0.834 rs7811446 chr7:148773226 G/T cg12479418 chr7:148823350 ZNF425;ZNF398 0.53 4.99 0.41 2.02e-6 Eosinophil counts;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil percentage of white cells; TGCT cis rs66561647 0.634 rs7821856 chr8:128939499 A/G cg11792826 chr8:129160931 MIR1208 0.21 4.8 0.4 4.53e-6 Hemoglobin concentration; TGCT cis rs1799949 1.000 rs11653231 chr17:41331460 G/A cg19454999 chr17:41278357 BRCA1;NBR2 0.49 5.2 0.42 8.14e-7 Menopause (age at onset); TGCT cis rs7647973 1.000 rs11720542 chr3:49357427 A/G cg07636037 chr3:49044803 WDR6 0.72 5.84 0.46 4.25e-8 Menarche (age at onset); TGCT cis rs79349575 0.749 rs318093 chr17:46989354 A/G cg26022315 chr17:47021804 SNF8 0.49 4.87 0.4 3.29e-6 Type 2 diabetes; TGCT cis rs9611565 0.568 rs5751159 chr22:42175365 G/A cg03806693 chr22:41940476 POLR3H 0.9 8.76 0.62 1.2e-14 Vitiligo; TGCT cis rs28386778 0.897 rs6504184 chr17:61842408 A/T cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs7666738 0.791 rs6532725 chr4:99061479 T/C cg18180107 chr4:99064573 C4orf37 0.58 5.25 0.43 6.44e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7197653 0.748 rs2279538 chr16:68397106 C/G cg05110241 chr16:68378359 PRMT7 -0.36 -4.46 -0.37 1.84e-5 Magnesium levels; TGCT cis rs514406 0.893 rs1242330 chr1:53396842 T/G cg08736216 chr1:53307985 ZYG11A -0.29 -6.09 -0.48 1.32e-8 Monocyte count; TGCT cis rs302972 0.826 rs303001 chr6:25056769 A/G cg18428180 chr6:24646492 KIAA0319 -1.03 -4.51 -0.38 1.49e-5 Creatinine levels in ischemic stroke; TGCT cis rs6460942 0.915 rs6460907 chr7:12304449 G/A cg06484146 chr7:12443880 VWDE -0.43 -4.61 -0.38 9.7e-6 Coronary artery disease; TGCT cis rs769267 0.965 rs2315281 chr19:19480099 G/A cg08509172 chr19:19383838 TM6SF2 0.35 4.69 0.39 7.2e-6 Tonsillectomy; TGCT cis rs9952991 0.941 rs1893217 chr18:12809340 A/G cg24737193 chr18:12778029 NA -0.51 -5.38 -0.43 3.65e-7 Inflammatory skin disease; TGCT cis rs7666738 0.830 rs11722272 chr4:99000839 C/T cg17366294 chr4:99064904 C4orf37 0.66 6.36 0.5 3.54e-9 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.679 rs499239 chr1:53310594 A/G cg22166914 chr1:53195759 ZYG11B 0.36 5.71 0.46 8.05e-8 Monocyte count; TGCT cis rs12142240 0.698 rs72677587 chr1:46813982 G/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs8103278 0.507 rs62111759 chr19:46296230 A/T cg14061069 chr19:46274453 DMPK 0.62 10.75 0.69 1.95e-19 Coronary artery disease; TGCT cis rs789852 0.681 rs789855 chr3:194329272 G/T cg18000598 chr3:194342907 TMEM44 -0.65 -4.88 -0.4 3.25e-6 QT interval; TGCT cis rs35883536 1.000 rs6681906 chr1:101086414 C/T cg06223162 chr1:101003688 GPR88 0.31 4.89 0.4 3.07e-6 Monocyte count; TGCT cis rs7772486 0.846 rs1331636 chr6:146338826 T/C cg13319975 chr6:146136371 FBXO30 -0.51 -4.56 -0.38 1.23e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs727563 0.636 rs2187795 chr22:42092225 C/A cg17554472 chr22:41940697 POLR3H 0.49 5.22 0.42 7.4e-7 Crohn's disease;Inflammatory bowel disease; TGCT cis rs514406 0.505 rs146750 chr1:53183447 C/G cg01802117 chr1:53393560 SCP2 -0.39 -4.61 -0.38 9.88e-6 Monocyte count; TGCT cis rs79349575 0.691 rs28528789 chr17:46986616 C/T cg07967210 chr17:47022446 SNF8 -0.41 -5.44 -0.44 2.69e-7 Type 2 diabetes; TGCT cis rs10504229 0.953 rs116564484 chr8:58172818 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs853679 0.546 rs55690788 chr6:28436145 T/C cg10876282 chr6:28092338 ZSCAN16 0.86 4.46 0.37 1.8e-5 Depression; TGCT cis rs28386778 0.897 rs2584624 chr17:61904546 A/G cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs9928842 0.882 rs9319481 chr16:75259478 T/C cg09066997 chr16:75300724 BCAR1 0.28 5.01 0.41 1.85e-6 Alcoholic chronic pancreatitis; TGCT cis rs2067615 0.579 rs10861665 chr12:107193836 T/C cg15890332 chr12:107067104 RFX4 0.28 5.61 0.45 1.27e-7 Heart rate; TGCT cis rs12908161 0.959 rs34342559 chr15:85331271 A/G cg17173187 chr15:85201210 NMB 0.55 6.11 0.48 1.17e-8 Schizophrenia; TGCT cis rs28386778 0.863 rs2727288 chr17:61901197 T/A cg11494091 chr17:61959527 GH2 0.61 14.43 0.79 2.59e-28 Prudent dietary pattern; TGCT cis rs3947 1.000 rs1736085 chr8:11703659 T/C cg02840367 chr8:11660030 FDFT1 0.9 6.51 0.5 1.64e-9 Blood protein levels; TGCT cis rs2276314 0.857 rs62101393 chr18:33592168 T/C cg19628046 chr18:33552617 C18orf21 0.51 4.46 0.37 1.79e-5 Endometriosis;Drug-induced torsades de pointes; TGCT cis rs11711311 1.000 rs9828099 chr3:113518402 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs873946 0.648 rs12783354 chr10:134557235 T/A cg05985448 chr10:134359359 INPP5A 0.24 5.13 0.42 1.1e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs644799 0.710 rs12273579 chr11:95524421 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.81 8.5 0.61 5.03e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs8177253 0.632 rs6782523 chr3:133438917 C/T cg11941060 chr3:133502564 NA -0.26 -5.28 -0.43 5.54e-7 Iron status biomarkers; TGCT cis rs2204008 0.744 rs11514073 chr12:38399553 A/C cg26384229 chr12:38710491 ALG10B 0.84 7.42 0.55 1.62e-11 Bladder cancer; TGCT cis rs28386778 1.000 rs2665810 chr17:61970210 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.51 -4.69 -0.39 7.17e-6 Prudent dietary pattern; TGCT cis rs6840360 0.642 rs11099815 chr4:152343888 G/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.41 -0.5 2.8e-9 Intelligence (multi-trait analysis); TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg22520471 chr17:61851767 DDX42;CCDC47 0.56 5.03 0.41 1.69e-6 Prudent dietary pattern; TGCT cis rs6840360 0.571 rs4696101 chr4:152528513 A/G cg17479576 chr4:152424074 FAM160A1 -0.73 -8.0 -0.58 7.69e-13 Intelligence (multi-trait analysis); TGCT cis rs10392 0.571 rs4812350 chr20:37631192 C/T cg27552599 chr20:37590471 DHX35 0.37 4.59 0.38 1.05e-5 Alcohol dependence or chronic alcoholic pancreatitis or alcohol-related liver cirrhosis; TGCT cis rs28386778 0.897 rs2584627 chr17:61901439 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.42 1.34e-6 Prudent dietary pattern; TGCT cis rs2115630 0.653 rs61394864 chr15:85170174 T/C cg17173187 chr15:85201210 NMB -0.47 -5.91 -0.47 3.05e-8 P wave terminal force; TGCT cis rs1857353 1.000 rs1913118 chr1:75886670 C/A cg11838876 chr1:75668600 SLC44A5 -0.51 -4.81 -0.4 4.23e-6 Whole-brain volume (Alzheimer's disease interaction); TGCT cis rs2718812 0.792 rs1867504 chr3:133410661 C/T cg16414030 chr3:133502952 NA -0.39 -5.14 -0.42 1.06e-6 Iron status biomarkers; TGCT cis rs2439831 0.681 rs511673 chr15:43618863 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.89 6.63 0.51 9.35e-10 Lung cancer in ever smokers; TGCT cis rs9929218 0.954 rs35794312 chr16:68827785 G/A cg03880890 chr16:69439245 NA -0.22 -4.47 -0.37 1.74e-5 Colorectal cancer; TGCT cis rs17270561 0.779 rs12210620 chr6:25884785 T/C cg17042849 chr6:26104293 HIST1H4C -0.78 -5.52 -0.44 1.92e-7 Iron status biomarkers; TGCT cis rs6089584 1.000 rs6089587 chr20:60564829 C/T cg13770153 chr20:60521292 NA -0.44 -5.69 -0.46 8.52e-8 Body mass index; TGCT cis rs11711311 1.000 rs6792447 chr3:113508335 T/C cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.76 -7.16 -0.54 6.29e-11 IgG glycosylation; TGCT cis rs6752107 1.000 rs6708373 chr2:234172846 A/G cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.19 4.65 0.39 8.35e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9303401 0.659 rs34913878 chr17:56897094 A/G cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs597539 0.652 rs546382 chr11:68704264 C/T cg06112835 chr11:68658793 MRPL21 0.48 8.14 0.59 3.49e-13 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs9467773 1.000 rs9467774 chr6:26505036 C/A cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.5e-9 Intelligence (multi-trait analysis); TGCT cis rs11105298 0.891 rs11105316 chr12:89925200 T/G cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.17 -0.42 8.99e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT trans rs941408 1.000 rs4807332 chr19:2793289 T/C cg19676328 chr12:49525230 TUBA1B -0.76 -7.65 -0.57 4.74e-12 Total cholesterol levels; TGCT cis rs4499344 0.730 rs12460663 chr19:33098238 T/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.85 8.76 0.62 1.23e-14 Mean platelet volume; TGCT cis rs6988636 0.536 rs16898043 chr8:124155886 A/G cg23067535 chr8:124195133 FAM83A -0.37 -4.95 -0.41 2.39e-6 Urinary uromodulin levels; TGCT cis rs28386778 0.897 rs2584640 chr17:61863488 C/T cg26338869 chr17:61819248 STRADA -0.53 -4.87 -0.4 3.29e-6 Prudent dietary pattern; TGCT cis rs4975709 0.589 rs4975746 chr5:1861069 G/A cg15595755 chr5:1867978 NA 0.46 5.29 0.43 5.29e-7 Cardiovascular disease risk factors; TGCT cis rs12780845 0.505 rs7085742 chr10:17248828 G/C cg01003015 chr10:17271136 VIM -0.6 -5.53 -0.44 1.83e-7 Homocysteine levels; TGCT cis rs10256972 0.630 rs13235747 chr7:1129123 T/C cg16145915 chr7:1198662 ZFAND2A -0.54 -6.95 -0.53 1.86e-10 Longevity;Endometriosis; TGCT cis rs2760061 0.598 rs849904 chr1:228137145 G/C cg18477163 chr1:228402036 OBSCN -0.32 -6.34 -0.49 3.86e-9 Diastolic blood pressure; TGCT cis rs9906944 0.713 rs9899580 chr17:47106878 T/G cg20966754 chr17:47091339 IGF2BP1 -0.45 -5.17 -0.42 9.27e-7 Intelligence (multi-trait analysis);Body fat percentage; TGCT cis rs7647973 1.000 rs13322887 chr3:49555583 G/A cg06212747 chr3:49208901 KLHDC8B -0.54 -4.45 -0.37 1.87e-5 Menarche (age at onset); TGCT cis rs2739330 0.929 rs5751777 chr22:24267047 C/T cg12419862 chr22:24373484 LOC391322 -0.84 -9.1 -0.63 1.92e-15 Liver enzyme levels (gamma-glutamyl transferase); TGCT trans rs4819388 0.915 rs7278940 chr21:45648992 C/T cg17383793 chr5:52405638 MOCS2 -0.67 -6.82 -0.52 3.49e-10 Celiac disease; TGCT cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg23758822 chr17:41437982 NA 0.69 6.37 0.5 3.34e-9 Menopause (age at onset); TGCT cis rs7246657 0.678 rs2927740 chr19:38140966 A/G cg03611452 chr19:38183253 ZNF781 -0.57 -4.79 -0.39 4.72e-6 Coronary artery calcification; TGCT cis rs13191362 0.935 rs34934114 chr6:163082480 G/A cg06582575 chr6:163149167 PACRG;PARK2 0.91 6.97 0.53 1.69e-10 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs514406 0.505 rs436363 chr1:53172163 T/C cg01802117 chr1:53393560 SCP2 -0.41 -4.69 -0.39 7.1e-6 Monocyte count; TGCT cis rs76419734 0.558 rs10019217 chr4:106588509 C/T cg24545054 chr4:106630052 GSTCD;INTS12 0.81 5.36 0.43 3.9e-7 Post bronchodilator FEV1; TGCT cis rs4919044 0.808 rs9419765 chr10:94798171 C/T cg05127821 chr10:94822908 CYP26C1 -0.74 -4.83 -0.4 3.95e-6 Coronary artery disease; TGCT cis rs637571 0.522 rs12792888 chr11:65761446 C/T cg02427764 chr11:65769310 BANF1;EIF1AD 0.66 6.54 0.51 1.45e-9 Eosinophil percentage of white cells; TGCT cis rs911263 0.961 rs17105278 chr14:68728479 T/C cg18825221 chr14:68749962 RAD51L1 -0.27 -5.24 -0.43 6.56e-7 Primary biliary cholangitis; TGCT cis rs9810089 0.814 rs2688600 chr3:136252596 C/A cg12473912 chr3:136751656 NA 0.35 4.79 0.4 4.67e-6 Gestational age at birth (child effect); TGCT cis rs6570726 0.791 rs6570692 chr6:145904401 T/A cg05347473 chr6:146136440 FBXO30 0.52 4.95 0.41 2.33e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs7949030 0.653 rs17773169 chr11:62318530 G/T cg22862634 chr11:62369728 EML3;MTA2 0.72 9.17 0.64 1.28e-15 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs68170813 0.559 rs10953530 chr7:106827796 A/C cg02696742 chr7:106810147 HBP1 -0.72 -6.05 -0.48 1.56e-8 Coronary artery disease; TGCT cis rs10875595 0.691 rs1076361 chr5:140674609 C/T cg24830062 chr5:140700576 TAF7 -0.73 -6.13 -0.48 1.1e-8 Pulmonary function decline; TGCT cis rs478304 0.934 rs537786 chr11:65494987 C/T cg17480646 chr11:65405466 SIPA1 0.42 5.02 0.41 1.78e-6 Acne (severe); TGCT cis rs7923452 0.938 rs602473 chr10:30781996 T/C cg18806716 chr10:30721971 MAP3K8 -0.69 -6.09 -0.48 1.32e-8 Itch intensity from mosquito bite; TGCT cis rs548987 0.529 rs1165165 chr6:25862466 C/T cg03517284 chr6:25882590 NA -0.6 -4.92 -0.4 2.7e-6 Homocysteine levels; TGCT cis rs78487399 0.808 rs7581586 chr2:43668176 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9858542 0.953 rs9814873 chr3:49454112 A/G cg03060546 chr3:49711283 APEH -0.62 -5.41 -0.44 3.09e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs13223928 0.572 rs16870744 chr7:3135781 G/A cg19214707 chr7:3157722 NA -0.43 -5.72 -0.46 7.3900000000000007e-08 Eosinophil percentage of white cells;Sum eosinophil basophil counts;Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes;Eosinophil counts; TGCT cis rs6690583 0.623 rs12047435 chr1:85452927 T/G cg20280350 chr1:85513789 MCOLN3 -0.69 -4.67 -0.39 7.58e-6 Serum sulfate level; TGCT cis rs7647973 0.626 rs4855849 chr3:49653378 A/G cg03034192 chr3:50606346 HEMK1;C3orf18 0.36 4.75 0.39 5.61e-6 Menarche (age at onset); TGCT cis rs3796352 1.000 rs114562844 chr3:52991584 C/T cg07884673 chr3:53033167 SFMBT1 0.6 5.53 0.44 1.82e-7 Immune reponse to smallpox (secreted IL-2); TGCT cis rs624899 0.655 rs8109248 chr19:11641375 C/T cg01045132 chr19:11649571 CNN1 0.63 6.39 0.5 2.98e-9 Presence of antiphospholipid antibodies; TGCT cis rs9653442 0.675 rs2871326 chr2:100662010 T/C cg22139774 chr2:100720529 AFF3 -0.42 -7.45 -0.56 1.36e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7618915 0.524 rs35249778 chr3:52661640 G/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg12310025 chr6:25882481 NA -0.62 -5.69 -0.45 8.78e-8 Intelligence (multi-trait analysis); TGCT cis rs4987668 0.655 rs4252381 chr7:142629375 G/T cg21621906 chr7:142494914 NA -0.9 -4.62 -0.38 9.48e-6 Cancer; TGCT cis rs2708977 0.637 rs687950 chr2:97069612 C/G cg01950434 chr2:97203154 ARID5A 0.54 4.58 0.38 1.13e-5 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs12530845 0.945 rs73725433 chr7:135313251 C/T cg23117316 chr7:135346802 PL-5283 -0.51 -4.83 -0.4 3.98e-6 Red blood cell traits; TGCT cis rs2836974 0.831 rs6517521 chr21:40551588 A/G cg11890956 chr21:40555474 PSMG1 1.14 12.22 0.74 4.93e-23 Cognitive function; TGCT cis rs208520 0.661 rs704519 chr6:66801136 T/C cg07460842 chr6:66804631 NA -0.94 -9.81 -0.66 3.56e-17 Exhaled nitric oxide output; TGCT cis rs2361718 0.590 rs4527052 chr17:78140910 A/G cg09238746 chr17:78121135 EIF4A3 -0.77 -7.39 -0.55 1.88e-11 Yeast infection; TGCT cis rs958025 1 rs958025 chr15:78759348 C/T cg24631222 chr15:78858424 CHRNA5 0.61 4.51 0.38 1.5e-5 Post bronchodilator FEV1/FVC ratio;Post bronchodilator FEV1; TGCT cis rs10504229 0.681 rs11779172 chr8:58045538 A/G cg21724239 chr8:58056113 NA 0.34 4.54 0.38 1.31e-5 Developmental language disorder (linguistic errors); TGCT cis rs711245 0.573 rs11899523 chr2:36800918 T/C cg10546459 chr2:36825355 FEZ2 0.57 5.18 0.42 8.89e-7 Height; TGCT cis rs17076896 0.786 rs17080523 chr13:19932538 T/C cg00777926 chr13:20807375 GJB6 -0.37 -4.53 -0.38 1.36e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs11822910 1.000 rs2439448 chr11:57199211 T/C cg00522883 chr11:57194120 SLC43A3 0.33 4.87 0.4 3.37e-6 Platelet distribution width; TGCT cis rs9303401 0.614 rs62084387 chr17:57148027 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.83 0.46 4.42e-8 Cognitive test performance; TGCT cis rs7809950 1.000 rs2066735 chr7:107188719 G/T cg23024343 chr7:107201750 COG5 -0.31 -4.82 -0.4 4.03e-6 Coronary artery disease; TGCT cis rs5769765 1.000 rs2319458 chr22:50236306 G/A cg22709217 chr22:50311962 ALG12;CRELD2 -1.09 -11.81 -0.73 5.01e-22 Schizophrenia; TGCT cis rs7923609 0.703 rs7100413 chr10:65330208 T/C cg08743896 chr10:65200160 JMJD1C 0.32 4.46 0.37 1.82e-5 Educational attainment;Liver enzyme levels (alkaline phosphatase); TGCT cis rs11098499 0.866 rs12513310 chr4:120288039 T/A cg09307838 chr4:120376055 NA 0.58 5.76 0.46 6.16e-8 Corneal astigmatism; TGCT cis rs17376456 0.825 rs10061377 chr5:93174513 T/C cg25358565 chr5:93447407 FAM172A 0.95 7.62 0.56 5.63e-12 Diabetic retinopathy; TGCT cis rs10504229 0.681 rs11779172 chr8:58045538 A/G cg08280861 chr8:58055591 NA 0.4 5.57 0.45 1.49e-7 Developmental language disorder (linguistic errors); TGCT cis rs5769765 1.000 rs768619 chr22:50287266 C/T cg15316289 chr22:50310904 ALG12;CRELD2 0.4 6.02 0.48 1.81e-8 Schizophrenia; TGCT cis rs7714584 1.000 rs6579804 chr5:150255931 T/C cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT trans rs4650994 1.000 rs4650995 chr1:178517316 C/T cg05059571 chr16:84539110 KIAA1609 -0.4 -7.43 -0.56 1.52e-11 HDL cholesterol levels;HDL cholesterol; TGCT cis rs2710642 0.821 rs2710639 chr2:63138963 C/T cg17519650 chr2:63277830 OTX1 0.58 4.98 0.41 2.11e-6 LDL cholesterol levels;LDL cholesterol; TGCT cis rs12497850 0.897 rs9681717 chr3:48872998 A/G cg07636037 chr3:49044803 WDR6 0.93 10.13 0.67 6.03e-18 Parkinson's disease; TGCT cis rs7666738 0.830 rs28818180 chr4:98953625 A/G cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs6565180 0.962 rs11642676 chr16:30371655 C/G cg17640201 chr16:30407289 ZNF48 -0.87 -8.21 -0.59 2.4e-13 Tonsillectomy; TGCT cis rs75686122 0.892 rs4734715 chr8:104508013 C/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs6540559 0.673 rs7550857 chr1:209956542 C/A cg23283495 chr1:209979779 IRF6 0.67 5.11 0.42 1.18e-6 Cleft lip with or without cleft palate; TGCT cis rs6951245 0.554 rs11544331 chr7:1131411 C/T cg23708337 chr7:1209742 NA 0.44 4.87 0.4 3.27e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10479542 0.549 rs4376229 chr5:179042971 A/G cg05457628 chr5:178986728 RUFY1 0.53 5.85 0.47 4.03e-8 Lung cancer; TGCT cis rs694739 0.892 rs647152 chr11:64109118 T/G cg23796481 chr11:64053134 BAD;GPR137 0.63 6.48 0.5 1.92e-9 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs1865760 0.516 rs9393683 chr6:26066198 A/G cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.77 7.45 0.56 1.42e-11 Height; TGCT cis rs28595532 0.800 rs67686161 chr4:119336720 C/T cg21605333 chr4:119757512 SEC24D 0.85 5.43 0.44 2.84e-7 Cannabis dependence symptom count; TGCT cis rs2070488 1.000 rs1841777 chr3:38484819 T/C cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.9 9.66 0.66 8.59e-17 Electrocardiographic conduction measures; TGCT cis rs6840360 0.642 rs11729923 chr4:152392036 G/T cg17479576 chr4:152424074 FAM160A1 -0.6 -6.4 -0.5 2.84e-9 Intelligence (multi-trait analysis); TGCT cis rs1348850 0.874 rs13013752 chr2:178456862 A/G cg22681709 chr2:178499509 PDE11A -0.4 -4.97 -0.41 2.18e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs9787249 0.957 rs6670841 chr1:40220284 C/G cg24920358 chr1:40204285 PPIE 0.57 10.63 0.69 3.68e-19 Blood protein levels; TGCT cis rs7726839 0.574 rs12517345 chr5:628294 G/A cg20362242 chr5:692897 TPPP 0.52 4.65 0.39 8.29e-6 Obesity-related traits; TGCT cis rs9393777 0.513 rs6913660 chr6:27091425 C/A cg16898833 chr6:26189333 HIST1H4D 0.8 4.85 0.4 3.57e-6 Intelligence (multi-trait analysis); TGCT cis rs1903068 0.927 rs12331507 chr4:56011889 A/G cg09978860 chr4:56023921 NA -0.51 -5.58 -0.45 1.42e-7 Endometriosis; TGCT cis rs3785574 0.962 rs56295011 chr17:61850359 A/G cg23090583 chr17:61904693 PSMC5;FTSJ3 0.62 5.84 0.46 4.39e-8 Height; TGCT cis rs9952991 0.608 rs9960807 chr18:12770851 A/G cg24737193 chr18:12778029 NA -0.53 -4.68 -0.39 7.28e-6 Inflammatory skin disease; TGCT cis rs7237497 0.532 rs515151 chr18:12860934 G/C cg23544223 chr18:12777786 NA 0.55 4.85 0.4 3.57e-6 Inflammatory skin disease; TGCT cis rs10504229 1.000 rs59071610 chr8:58186301 A/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.27 -0.43 5.94e-7 Developmental language disorder (linguistic errors); TGCT cis rs7584330 0.826 rs7604315 chr2:238381729 C/G cg14458575 chr2:238380390 NA 0.54 8.7 0.62 1.69e-14 Prostate cancer; TGCT cis rs1903068 0.719 rs9284955 chr4:56003117 A/G cg01777861 chr4:56023843 NA -0.53 -5.73 -0.46 7.13e-8 Endometriosis; TGCT cis rs10435719 0.902 rs7459545 chr8:11804389 G/T cg02840367 chr8:11660030 FDFT1 -0.52 -4.48 -0.37 1.7e-5 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs9914988 0.943 rs4794839 chr17:27131393 G/A cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs1453308 1.000 rs1377444 chr2:237183481 A/G cg19324714 chr2:237145437 ASB18 0.58 5.13 0.42 1.11e-6 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs7226408 0.802 rs72887095 chr18:34508949 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs12477438 0.765 rs13406288 chr2:99589585 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 -0.57 -4.88 -0.4 3.17e-6 Chronic sinus infection; TGCT cis rs9388451 0.626 rs9385383 chr6:126086290 G/T cg05901451 chr6:126070800 HEY2 -0.96 -12.17 -0.74 6.58e-23 Brugada syndrome; TGCT cis rs6951245 1.000 rs11767527 chr7:1097394 T/C cg27454412 chr7:1067447 C7orf50 0.6 4.72 0.39 6.32e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7829975 0.807 rs519019 chr8:8595104 A/T cg15556689 chr8:8085844 FLJ10661 -0.65 -5.67 -0.45 9.5e-8 Mood instability; TGCT trans rs1814175 0.817 rs12290508 chr11:49621037 C/T cg15704280 chr7:45808275 SEPT13 -0.73 -8.64 -0.61 2.35e-14 Height; TGCT cis rs57920188 0.535 rs112660254 chr1:4089921 T/G cg20703997 chr1:4087676 NA 0.49 6.2 0.49 7.57e-9 Interleukin-17 levels; TGCT cis rs727505 0.865 rs17325193 chr7:124648385 A/G cg23710748 chr7:124431027 NA -0.26 -4.55 -0.38 1.27e-5 Lewy body disease; TGCT cis rs6459788 0.585 rs6950818 chr7:157235364 C/G cg03453431 chr7:157225567 NA -0.5 -7.79 -0.57 2.3e-12 Epstein-Barr virus copy number in lymphoblastoid cell lines; TGCT cis rs4803468 0.763 rs17318596 chr19:41937095 A/G cg09537434 chr19:41945824 ATP5SL -0.9 -9.53 -0.65 1.74e-16 Height; TGCT cis rs79349575 0.721 rs3744608 chr17:46993233 C/G cg00947319 chr17:47005597 UBE2Z -0.19 -4.51 -0.38 1.48e-5 Type 2 diabetes; TGCT cis rs4478858 0.660 rs10798844 chr1:31819128 A/G cg00250761 chr1:31883323 NA -0.29 -5.12 -0.42 1.13e-6 Alcohol dependence; TGCT cis rs1670533 1.000 rs6599278 chr4:1058798 C/T cg20887711 chr4:1340912 KIAA1530 0.69 5.69 0.46 8.55e-8 Recombination rate (females); TGCT cis rs1023500 0.956 rs1894713 chr22:42335621 G/A cg04692870 chr22:42525206 CYP2D6 -0.35 -5.22 -0.42 7.18e-7 Schizophrenia; TGCT cis rs7666738 0.830 rs62321565 chr4:98976571 G/A cg17366294 chr4:99064904 C4orf37 0.68 6.94 0.53 1.95e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs4819052 0.851 rs7279182 chr21:46656112 G/A cg02159808 chr21:46707872 POFUT2;LOC642852 0.57 4.76 0.39 5.4e-6 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs7647973 0.600 rs12631989 chr3:49273996 C/T cg18654377 chr3:49208889 KLHDC8B -0.38 -5.03 -0.41 1.69e-6 Menarche (age at onset); TGCT cis rs12142240 0.698 rs66483119 chr1:46838389 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs9733 0.596 rs6681990 chr1:150695929 A/G cg09365446 chr1:150670422 GOLPH3L 0.3 4.52 0.38 1.4e-5 Tonsillectomy; TGCT cis rs6121246 0.542 rs2376990 chr20:30238744 G/A cg13852791 chr20:30311386 BCL2L1 0.69 4.45 0.37 1.9e-5 Mean corpuscular hemoglobin; TGCT cis rs7209700 0.644 rs7214468 chr17:45370766 G/A cg21624342 chr17:45890973 OSBPL7 0.18 5.1 0.42 1.24e-6 IgG glycosylation; TGCT cis rs62064224 0.702 rs2302277 chr17:30791509 C/G cg09324608 chr17:30823087 MYO1D 0.22 4.45 0.37 1.89e-5 Schizophrenia; TGCT cis rs35306767 0.714 rs66797613 chr10:1090469 C/T cg20503657 chr10:835505 NA 0.6 6.93 0.53 2e-10 Eosinophil percentage of granulocytes; TGCT cis rs477895 0.713 rs11601024 chr11:63943074 A/G cg19465662 chr11:63993652 NUDT22;TRPT1 0.8 6.5 0.5 1.75e-9 Mean platelet volume; TGCT cis rs840163 0.512 rs4759260 chr12:57265375 G/A cg20779414 chr12:57505882 STAT6 -0.44 -4.87 -0.4 3.31e-6 Alzheimer's disease (survival time); TGCT cis rs2019137 0.936 rs731834 chr2:113957198 A/C cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -8.2 -0.59 2.52e-13 Lymphocyte counts; TGCT cis rs2235642 0.717 rs9937922 chr16:1658154 C/G cg11375102 chr16:1583810 IFT140;TMEM204 -0.27 -4.66 -0.39 7.88e-6 Coronary artery disease; TGCT cis rs860295 0.557 rs12037177 chr1:155877029 C/T cg13795986 chr1:155880507 RIT1 -0.37 -4.47 -0.37 1.72e-5 Body mass index; TGCT cis rs1520333 0.918 rs11994210 chr8:79344992 A/G cg16589705 chr8:80226364 NA -0.3 -4.47 -0.37 1.74e-5 Multiple sclerosis; TGCT cis rs9467603 1.000 rs6940698 chr6:25821580 A/G cg16898833 chr6:26189333 HIST1H4D -1.13 -5.87 -0.47 3.65e-8 Intelligence (multi-trait analysis); TGCT cis rs12451471 0.559 rs12452263 chr17:78079310 T/C cg06718696 chr17:78121285 EIF4A3 0.71 5.89 0.47 3.42e-8 Plateletcrit;Mean corpuscular hemoglobin concentration; TGCT cis rs7267979 0.509 rs6115218 chr20:25566485 A/G cg15001687 chr20:25566336 NINL 0.45 5.03 0.41 1.7e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7618915 0.508 rs11717043 chr3:52656092 A/T cg11041457 chr3:52719354 GNL3;PBRM1 0.61 6.07 0.48 1.47e-8 Bipolar disorder; TGCT cis rs2067615 0.579 rs10861655 chr12:107129419 A/G cg15890332 chr12:107067104 RFX4 -0.28 -5.63 -0.45 1.15e-7 Heart rate; TGCT cis rs453301 0.592 rs4841084 chr8:8883905 C/T cg15556689 chr8:8085844 FLJ10661 0.82 7.24 0.55 4.15e-11 Joint mobility (Beighton score); TGCT cis rs2663905 0.664 rs2460855 chr15:81361729 G/T cg27045999 chr15:81426544 C15orf26 -0.53 -5.06 -0.41 1.46e-6 QT interval (drug interaction); TGCT cis rs514406 0.708 rs536621 chr1:53309097 A/G cg08736216 chr1:53307985 ZYG11A -0.25 -4.68 -0.39 7.33e-6 Monocyte count; TGCT cis rs7809950 0.834 rs3801946 chr7:107242995 T/A cg23024343 chr7:107201750 COG5 0.33 5.29 0.43 5.36e-7 Coronary artery disease; TGCT cis rs13242816 1.000 rs34325296 chr7:116122409 C/T cg02799643 chr7:116139180 CAV2 -0.49 -5.53 -0.45 1.78e-7 P wave duration; TGCT cis rs4851254 0.660 rs58683655 chr2:100686519 G/C cg22139774 chr2:100720529 AFF3 -0.45 -4.91 -0.4 2.75e-6 Intelligence (multi-trait analysis); TGCT cis rs7618915 0.547 rs11709448 chr3:52647449 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.54 -0.38 1.33e-5 Bipolar disorder; TGCT cis rs1218582 0.772 rs2061690 chr1:154919080 C/T cg06418219 chr1:154948305 SHC1;CKS1B -0.64 -6.55 -0.51 1.35e-9 Prostate cancer; TGCT cis rs3741404 0.609 rs592271 chr11:63872029 G/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.72 7.39 0.55 1.89e-11 Platelet count; TGCT cis rs7568458 0.684 rs60012532 chr2:85752474 A/C cg02493740 chr2:85810744 VAMP5 -0.29 -5.68 -0.45 9.08e-8 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs9467773 1.000 rs4713008 chr6:26538268 T/C cg05738196 chr6:26577821 NA 0.88 12.5 0.75 1.03e-23 Intelligence (multi-trait analysis); TGCT cis rs3764400 0.567 rs12939334 chr17:46302669 A/G cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs10256972 0.621 rs10951594 chr7:1088607 C/G cg03188948 chr7:1209495 NA 0.47 6.15 0.48 9.79e-9 Longevity;Endometriosis; TGCT cis rs951366 0.589 rs823099 chr1:205669322 C/A cg14893161 chr1:205819251 PM20D1 0.53 7.0 0.53 1.39e-10 Menarche (age at onset); TGCT cis rs2762353 0.935 rs1165152 chr6:25818766 A/G cg03517284 chr6:25882590 NA -0.53 -5.43 -0.44 2.88e-7 Blood metabolite levels; TGCT cis rs9653442 0.866 rs11123811 chr2:100760172 T/C cg07810366 chr2:100720526 AFF3 -0.47 -8.04 -0.59 6.16e-13 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs7914558 1.000 rs10786740 chr10:104935593 G/C cg15744005 chr10:104629667 AS3MT -0.39 -4.75 -0.39 5.53e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6570726 0.791 rs422099 chr6:145806936 C/T cg05347473 chr6:146136440 FBXO30 0.51 4.72 0.39 6.14e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs453301 0.631 rs17700611 chr8:8793654 A/G cg06636001 chr8:8085503 FLJ10661 -0.67 -5.73 -0.46 7.16e-8 Joint mobility (Beighton score); TGCT cis rs7617773 1.000 rs6442109 chr3:48192981 G/A cg11946769 chr3:48343235 NME6 -0.59 -5.33 -0.43 4.54e-7 Coronary artery disease; TGCT cis rs7172809 0.863 rs74026932 chr15:77825729 T/C cg22256960 chr15:77711686 NA -0.44 -4.48 -0.37 1.67e-5 Glucose homeostasis traits; TGCT cis rs7264396 0.635 rs6060720 chr20:34548336 A/C cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.04 -0.41 1.58e-6 Total cholesterol levels; TGCT cis rs910316 0.904 rs7156089 chr14:75645527 A/G cg23033748 chr14:75592666 NEK9 -0.29 -4.88 -0.4 3.17e-6 Height; TGCT cis rs28785552 0.931 rs8113078 chr19:53239084 T/G cg10871876 chr19:53194124 ZNF83 0.6 8.76 0.62 1.2e-14 Response to paliperidone in schizophrenia (PANSS score); TGCT cis rs8077577 0.895 rs16960980 chr17:18100858 C/T cg09161412 chr17:18057145 MYO15A -0.6 -4.79 -0.4 4.59e-6 Obesity-related traits; TGCT cis rs7666738 0.830 rs62318470 chr4:98925846 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.85 0.46 4.16e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2486288 0.656 rs7165039 chr15:45570413 C/G cg26924012 chr15:45694286 SPATA5L1 -0.78 -7.55 -0.56 8e-12 Glomerular filtration rate; TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg14851468 chr5:179071604 C5orf60 0.27 5.56 0.45 1.59e-7 Lung cancer; TGCT cis rs7914558 0.966 rs1971589 chr10:104744406 A/G cg15744005 chr10:104629667 AS3MT -0.41 -5.08 -0.42 1.33e-6 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs6089829 0.925 rs6062396 chr20:61667949 T/C cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs7726839 0.507 rs111707179 chr5:593308 T/A cg16624210 chr5:671434 TPPP 0.45 4.92 0.4 2.71e-6 Obesity-related traits; TGCT trans rs208520 0.770 rs1342960 chr6:66883514 T/C cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.95 -10.37 -0.68 1.58e-18 Exhaled nitric oxide output; TGCT cis rs6964587 0.967 rs12531966 chr7:91765840 A/G cg17063962 chr7:91808500 NA 0.91 9.72 0.66 5.97e-17 Breast cancer; TGCT cis rs548181 0.609 rs511822 chr11:125534115 C/T cg03464685 chr11:125439445 EI24 1.38 9.91 0.66 2.14e-17 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs28386778 0.863 rs11649912 chr17:61797515 T/A cg06873352 chr17:61820015 STRADA 0.55 6.1 0.48 1.26e-8 Prudent dietary pattern; TGCT cis rs12477438 0.798 rs10196680 chr2:99628617 A/G cg15544633 chr2:99771531 LIPT1;TSGA10 -0.84 -8.52 -0.61 4.5e-14 Chronic sinus infection; TGCT cis rs4689592 0.554 rs3951346 chr4:7073321 C/T cg26116260 chr4:7069785 GRPEL1 1.1 10.75 0.69 1.89e-19 Monocyte percentage of white cells; TGCT cis rs7666738 0.753 rs6826709 chr4:98714553 C/G cg17366294 chr4:99064904 C4orf37 0.67 6.91 0.53 2.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7631605 0.905 rs72866099 chr3:37259646 C/A cg17445812 chr3:36986805 TRANK1 0.21 4.59 0.38 1.09e-5 Cerebrospinal P-tau181p levels; TGCT cis rs7613051 0.649 rs6777787 chr3:33057103 A/G cg19404215 chr3:33155277 CRTAP 0.53 4.53 0.38 1.34e-5 Atopic dermatitis; TGCT cis rs727505 1.000 rs2402751 chr7:124434760 C/T cg23710748 chr7:124431027 NA -0.25 -4.49 -0.37 1.6e-5 Lewy body disease; TGCT cis rs7100689 0.697 rs4934084 chr10:82116960 T/C cg01528321 chr10:82214614 TSPAN14 0.88 8.48 0.61 5.61e-14 Post bronchodilator FEV1; TGCT cis rs2797160 1.000 rs9491471 chr6:125991715 C/T cg05901451 chr6:126070800 HEY2 -0.74 -6.57 -0.51 1.23e-9 Endometrial cancer; TGCT cis rs8068544 0.818 rs8079958 chr17:40155467 C/T cg13092355 chr17:39992602 KLHL10;NT5C3L -0.95 -4.64 -0.38 8.56e-6 Reticulocyte fraction of red cells;Reticulocyte count; TGCT cis rs7959452 0.868 rs12812860 chr12:69746671 T/C cg20891283 chr12:69753455 YEATS4 0.69 6.81 0.52 3.67e-10 Blood protein levels; TGCT cis rs2862064 0.799 rs4704835 chr5:156443251 G/A cg12943317 chr5:156479607 HAVCR1 -0.36 -4.79 -0.39 4.73e-6 Platelet count; TGCT cis rs10751647 0.804 rs3809112 chr11:307036 C/T cg06046490 chr11:320940 IFITM3 0.29 4.95 0.41 2.35e-6 Monocyte count; TGCT cis rs1355023 0.547 rs6568402 chr6:106207093 A/G cg17356964 chr6:106582638 NA 0.27 4.86 0.4 3.48e-6 Age-related macular degeneration; TGCT cis rs9858542 0.953 rs1801143 chr3:49570200 C/T cg03060546 chr3:49711283 APEH -0.61 -5.37 -0.43 3.78e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs7937682 0.575 rs7114617 chr11:111768173 A/T cg09085632 chr11:111637200 PPP2R1B 0.91 8.56 0.61 3.6e-14 Primary sclerosing cholangitis; TGCT cis rs4253772 0.591 rs6008546 chr22:46686377 T/G cg24881330 chr22:46731750 TRMU 0.95 5.76 0.46 6.26e-8 LDL cholesterol;Cholesterol, total; TGCT cis rs9611565 0.569 rs188057 chr22:41822305 T/G cg17554472 chr22:41940697 POLR3H 0.49 5.16 0.42 9.72e-7 Vitiligo; TGCT cis rs3008870 1.000 rs2815371 chr1:67504313 A/G cg08660285 chr1:67390436 MIER1;WDR78 1.07 11.02 0.7 4.12e-20 Lymphocyte percentage of white cells; TGCT cis rs10751667 0.925 rs7115336 chr11:988101 C/G cg06064525 chr11:970664 AP2A2 -0.31 -6.16 -0.48 9.52e-9 Alzheimer's disease (late onset); TGCT cis rs9653442 0.675 rs961788 chr2:100641459 T/C cg22139774 chr2:100720529 AFF3 -0.41 -7.31 -0.55 2.85e-11 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs4853012 0.838 rs61521879 chr2:74346208 T/C cg01017244 chr2:74357527 NA 0.5 8.09 0.59 4.65e-13 Gestational age at birth (maternal effect); TGCT cis rs10927875 0.632 rs4661666 chr1:16162471 C/A cg21385522 chr1:16154831 NA -1.0 -17.61 -0.85 1.57e-35 Dilated cardiomyopathy; TGCT cis rs9467773 0.526 rs9688946 chr6:26367445 C/A cg05738196 chr6:26577821 NA -0.63 -6.61 -0.51 1.01e-9 Intelligence (multi-trait analysis); TGCT cis rs3806843 0.551 rs184996 chr5:140323773 T/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT trans rs9388451 0.626 rs1343115 chr6:126069817 C/G cg05039488 chr6:79577232 IRAK1BP1 -0.87 -9.71 -0.66 6.39e-17 Brugada syndrome; TGCT cis rs10986311 0.537 rs10818938 chr9:127049237 G/A cg14243010 chr9:127117328 LOC100129034;PSMB7 -0.19 -4.58 -0.38 1.09e-5 Vitiligo; TGCT cis rs7223966 0.729 rs7921 chr17:62006259 G/A cg18032289 chr17:61959525 GH2 -0.3 -4.46 -0.37 1.81e-5 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs17102423 0.594 rs2781373 chr14:65568215 G/A cg11161011 chr14:65562177 MAX -0.47 -6.44 -0.5 2.41e-9 Obesity-related traits; TGCT cis rs7914558 1.000 rs10786733 chr10:104794947 G/A cg04362960 chr10:104952993 NT5C2 0.62 5.51 0.44 1.97e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4595586 0.545 rs11615634 chr12:39364704 A/C cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs477895 0.653 rs2875749 chr11:63903878 C/A cg23719950 chr11:63933701 MACROD1 -0.71 -5.91 -0.47 3.06e-8 Mean platelet volume; TGCT cis rs873946 0.586 rs12251911 chr10:134570595 A/G cg27286337 chr10:134555280 INPP5A 0.37 4.52 0.38 1.4e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs7131987 0.903 rs1035604 chr12:29393102 G/A cg09582351 chr12:29534625 ERGIC2 -0.24 -4.55 -0.38 1.26e-5 QT interval; TGCT cis rs3617 0.573 rs56383738 chr3:52908398 T/C cg11041457 chr3:52719354 GNL3;PBRM1 -0.51 -4.94 -0.41 2.46e-6 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs7666738 0.830 rs4619898 chr4:98959646 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9733 0.596 rs72702504 chr1:150635374 G/C cg04414720 chr1:150670196 GOLPH3L 0.39 5.04 0.41 1.58e-6 Tonsillectomy; TGCT cis rs73198271 0.740 rs964771 chr8:8650939 A/G cg15556689 chr8:8085844 FLJ10661 0.6 4.46 0.37 1.78e-5 Bone ultrasound measurement (broadband ultrasound attenuation); TGCT cis rs12682352 0.602 rs13260419 chr8:8675176 A/G cg15556689 chr8:8085844 FLJ10661 0.59 5.08 0.41 1.35e-6 Neuroticism; TGCT cis rs9419702 0.538 rs9419625 chr10:133534954 T/G cg20568497 chr10:133558893 NA 0.43 4.68 0.39 7.31e-6 Survival in rectal cancer; TGCT cis rs73201462 0.901 rs17282209 chr3:127715196 A/G cg06138505 chr3:127317209 MCM2 0.99 4.77 0.39 5.18e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio; TGCT trans rs4332037 0.851 rs34040190 chr7:1920356 G/A cg10840412 chr1:235813424 GNG4 1.06 8.3 0.6 1.53e-13 Bipolar disorder; TGCT trans rs56011263 0.687 rs4690292 chr4:703712 A/G cg12575136 chr18:32820987 ZNF397 0.79 9.62 0.65 1.06e-16 White blood cell count; TGCT cis rs763014 0.593 rs28455838 chr16:681966 T/C cg27436995 chr16:743998 FBXL16 -0.47 -5.12 -0.42 1.13e-6 Height; TGCT cis rs3771570 1.000 rs56156035 chr2:242205955 T/A cg21155796 chr2:242212141 HDLBP 0.94 6.69 0.51 6.9e-10 Prostate cancer; TGCT cis rs9457247 1.000 rs376551 chr6:167384923 G/A cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT trans rs783396 0.792 rs783416 chr6:106964765 C/T cg09013229 chr1:225332226 DNAH14 -0.53 -6.66 -0.51 8.13e-10 Stroke; TGCT cis rs7666738 0.546 rs13148080 chr4:98680947 A/G cg17366294 chr4:99064904 C4orf37 0.58 5.36 0.43 3.87e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs3858526 0.727 rs10769353 chr11:5954809 C/T cg13902645 chr11:5959945 NA 0.36 4.47 0.37 1.75e-5 DNA methylation (variation); TGCT cis rs11696845 0.626 rs4810439 chr20:43377870 C/G cg25301532 chr20:43378953 KCNK15 -0.46 -4.85 -0.4 3.58e-6 Obesity-related traits; TGCT cis rs1552244 0.882 rs13066757 chr3:10045030 C/A cg00149659 chr3:10157352 C3orf10 0.78 4.99 0.41 2.04e-6 Alzheimer's disease; TGCT cis rs6987853 0.814 rs2167338 chr8:42455079 A/G cg20539142 chr8:42623718 CHRNA6 -0.19 -4.63 -0.38 9.1e-6 Mean corpuscular hemoglobin concentration; TGCT cis rs6450176 0.638 rs3822497 chr5:53299693 C/G ch.5.1024479R chr5:53302184 ARL15 -0.76 -5.52 -0.44 1.92e-7 HDL cholesterol levels;HDL cholesterol;Adiponectin levels; TGCT cis rs28595532 0.920 rs17259173 chr4:119777232 T/C cg21605333 chr4:119757512 SEC24D 1.53 8.87 0.62 6.71e-15 Cannabis dependence symptom count; TGCT cis rs8033133 0.881 rs3803328 chr15:25330550 T/A cg14481604 chr15:25334117 SNORD116-22 -0.31 -6.95 -0.53 1.82e-10 Blood osmolality (transformed sodium); TGCT cis rs9926296 0.562 rs4785725 chr16:89893243 A/G cg26513180 chr16:89883248 FANCA 0.72 7.15 0.54 6.73e-11 Vitiligo; TGCT cis rs8038465 0.638 rs8036954 chr15:73974282 T/C cg15420318 chr15:73925796 NPTN 0.71 7.83 0.58 1.88e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1008375 1.000 rs6849704 chr4:17652031 G/C cg16339924 chr4:17578868 LAP3 0.63 5.33 0.43 4.49e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs12048904 0.964 rs3188491 chr1:101338482 A/G cg00063077 chr1:101360652 SLC30A7;EXTL2 0.48 4.62 0.38 9.44e-6 Multiple sclerosis; TGCT cis rs11971779 0.700 rs11763942 chr7:139005795 A/T cg07862535 chr7:139043722 LUC7L2 0.67 5.38 0.44 3.57e-7 Diisocyanate-induced asthma; TGCT cis rs4455778 0.580 rs4244231 chr7:49103406 G/A cg26309511 chr7:48887640 NA 0.5 6.49 0.5 1.87e-9 Lung cancer in never smokers; TGCT cis rs12497850 0.866 rs6791234 chr3:48996137 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 2.97e-7 Parkinson's disease; TGCT trans rs941408 1.000 rs941406 chr19:2803623 A/G cg19676328 chr12:49525230 TUBA1B -0.88 -8.09 -0.59 4.59e-13 Total cholesterol levels; TGCT cis rs7811142 1.000 rs7811142 chr7:100065443 A/T cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs17030434 0.953 rs74845915 chr4:154696778 G/T cg14289246 chr4:154710475 SFRP2 -0.95 -7.52 -0.56 9.48e-12 Electrocardiographic conduction measures; TGCT cis rs933688 1.000 rs6452951 chr5:90653868 T/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.99 9.32 0.64 5.44e-16 Smoking behavior; TGCT cis rs2688608 0.620 rs7080350 chr10:75577843 A/G cg04320760 chr10:75533139 FUT11 0.36 5.6 0.45 1.33e-7 Inflammatory bowel disease; TGCT trans rs6089829 0.816 rs6062397 chr20:61668268 A/G cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs7100689 0.622 rs2342816 chr10:82086546 G/A cg01528321 chr10:82214614 TSPAN14 0.75 7.49 0.56 1.15e-11 Post bronchodilator FEV1; TGCT cis rs9611565 0.504 rs5758452 chr22:42144927 G/A cg06481639 chr22:41940642 POLR3H 0.53 4.54 0.38 1.29e-5 Vitiligo; TGCT trans rs6089829 0.925 rs6062396 chr20:61667949 T/C cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs67311347 1.000 rs12492035 chr3:40467110 G/A cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs933688 1.000 rs4382199 chr5:90744228 A/G cg02339078 chr5:90679543 LOC100129716;ARRDC3 0.94 7.95 0.58 9.95e-13 Smoking behavior; TGCT trans rs1496653 0.602 rs58522464 chr3:23480731 G/A cg02770683 chr12:57597238 LRP1 0.38 6.89 0.53 2.53e-10 Type 2 diabetes; TGCT cis rs9527 0.590 rs10786744 chr10:104945028 A/C cg15744005 chr10:104629667 AS3MT 0.42 4.83 0.4 3.9e-6 Arsenic metabolism; TGCT cis rs4304924 0.500 rs7339081 chr13:79235501 A/G cg05295671 chr13:79234353 RNF219 0.82 6.68 0.51 7.27e-10 Large artery stroke; TGCT cis rs41307935 0.818 rs34339345 chr1:27226089 G/A cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.95e-6 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs778371 0.723 rs10210953 chr2:233698830 G/A cg08000102 chr2:233561755 GIGYF2 -0.72 -8.68 -0.61 1.91e-14 Schizophrenia; TGCT cis rs6490294 0.904 rs7295722 chr12:112394260 C/T cg10833066 chr12:111807467 FAM109A 0.38 5.61 0.45 1.24e-7 Mean platelet volume; TGCT cis rs9311474 0.508 rs12637627 chr3:52619962 G/T cg07507251 chr3:52567010 NT5DC2 0.47 6.64 0.51 8.82e-10 Electroencephalogram traits; TGCT cis rs12220238 0.915 rs10824148 chr10:76078014 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.28 0.49 5.18e-9 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs13256369 0.802 rs11995449 chr8:8559898 G/A cg18904891 chr8:8559673 CLDN23 0.56 5.0 0.41 1.94e-6 Obesity-related traits; TGCT cis rs9534288 0.619 rs1326397 chr13:46682122 T/C cg15192986 chr13:46630673 CPB2 -0.51 -6.11 -0.48 1.17e-8 Blood protein levels; TGCT cis rs861020 0.606 rs627459 chr1:210004682 C/G cg05527609 chr1:210001259 C1orf107 0.86 7.54 0.56 8.69e-12 Orofacial clefts; TGCT cis rs9486719 1.000 rs2142652 chr6:96868504 A/C cg18709589 chr6:96969512 KIAA0776 0.71 5.21 0.42 7.61e-7 Migraine;Coronary artery disease; TGCT cis rs67311347 0.956 rs9817233 chr3:40425618 G/T cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs4730250 0.707 rs257382 chr7:106804249 A/G cg02696742 chr7:106810147 HBP1 -0.7 -5.44 -0.44 2.74e-7 Osteoarthritis; TGCT cis rs1322512 1.000 rs1631457 chr6:152946514 C/T cg03415253 chr6:152958462 SYNE1 -0.57 -4.99 -0.41 2e-6 Tonometry; TGCT cis rs3008870 1.000 rs2009319 chr1:67481070 G/T cg03991309 chr1:68237761 GNG12 0.27 4.57 0.38 1.18e-5 Lymphocyte percentage of white cells; TGCT cis rs319204 0.959 rs319237 chr5:146240443 C/T cg25021259 chr5:146258546 PPP2R2B 0.36 4.53 0.38 1.37e-5 Schizophrenia; TGCT cis rs7582180 0.629 rs11686842 chr2:100956139 C/T cg14675211 chr2:100938903 LONRF2 0.5 4.78 0.39 4.81e-6 Intelligence (multi-trait analysis); TGCT cis rs2067615 0.507 rs1922432 chr12:107077232 G/A cg15890332 chr12:107067104 RFX4 0.27 5.21 0.42 7.58e-7 Heart rate; TGCT cis rs11696501 0.793 rs4812909 chr20:44167244 G/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.54 -0.38 1.33e-5 Brain structure; TGCT cis rs12579753 1.000 rs12580330 chr12:82241280 T/G cg07988820 chr12:82153109 PPFIA2 -0.6 -6.48 -0.5 1.91e-9 Resting heart rate; TGCT cis rs6952808 0.931 rs12537479 chr7:1868995 A/G cg22963979 chr7:1858916 MAD1L1 0.3 4.65 0.39 8.24e-6 Bipolar disorder and schizophrenia; TGCT cis rs651907 0.535 rs11717638 chr3:101505468 A/G cg12386194 chr3:101231763 SENP7 0.48 4.81 0.4 4.36e-6 Colorectal cancer; TGCT cis rs6951245 1.000 rs77868187 chr7:1093968 A/C cg03188948 chr7:1209495 NA 0.71 6.04 0.48 1.68e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9486719 1.000 rs2472880 chr6:96860130 G/A cg06623918 chr6:96969491 KIAA0776 1.01 8.86 0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs1865760 0.713 rs6928951 chr6:25995554 C/T cg16482183 chr6:26056742 HIST1H1C 0.54 4.77 0.39 5.15e-6 Height; TGCT cis rs2832191 0.720 rs4643617 chr21:30485278 T/C cg08807101 chr21:30365312 RNF160 -0.64 -6.01 -0.48 1.9e-8 Dental caries; TGCT cis rs8031584 0.723 rs11632229 chr15:31179534 A/G cg08109568 chr15:31115862 NA 0.38 4.98 0.41 2.12e-6 Huntington's disease progression; TGCT cis rs7818688 0.697 rs112411609 chr8:95980854 C/A cg16049864 chr8:95962084 TP53INP1 0.54 4.64 0.38 8.87e-6 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs7259965 0.582 rs3895941 chr19:41531212 T/C cg27089200 chr19:41531976 NA 0.52 6.7 0.52 6.45e-10 Midgestational circulating levels of PBDEs;Midgestational circulating levels of organochlorine pesticides; TGCT cis rs151997 1.000 rs32483 chr5:50205230 C/T cg06027927 chr5:50259733 NA 0.47 4.83 0.4 3.9e-6 Callous-unemotional behaviour; TGCT cis rs12142240 0.667 rs55887761 chr1:46826587 C/A cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs208520 0.802 rs4710314 chr6:66883656 G/A cg07460842 chr6:66804631 NA -0.9 -9.33 -0.64 5.29e-16 Exhaled nitric oxide output; TGCT cis rs2762353 0.935 rs1165153 chr6:25817789 A/G cg03517284 chr6:25882590 NA -0.53 -5.43 -0.44 2.88e-7 Blood metabolite levels; TGCT cis rs7267979 0.932 rs6138600 chr20:25521346 A/T cg03522245 chr20:25566470 NINL 0.6 6.46 0.5 2.14e-9 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2032447 0.714 rs199726 chr6:25953360 G/A cg12310025 chr6:25882481 NA -0.67 -5.99 -0.47 2.11e-8 Intelligence (multi-trait analysis); TGCT cis rs2832077 0.527 rs9981922 chr21:30212718 A/G cg24692254 chr21:30365293 RNF160 -0.6 -5.24 -0.43 6.82e-7 Cognitive test performance; TGCT cis rs4372836 0.729 rs7567861 chr2:29035849 C/T cg09522027 chr2:28974177 PPP1CB -0.7 -7.26 -0.55 3.68e-11 Body mass index; TGCT cis rs6921919 0.583 rs11751693 chr6:28345083 C/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.33 -0.43 4.48e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs11650494 0.908 rs117853079 chr17:47421593 G/C cg08112188 chr17:47440006 ZNF652 1.04 5.34 0.43 4.3e-7 Prostate cancer; TGCT cis rs651907 0.557 rs3094297 chr3:101399260 A/G cg12386194 chr3:101231763 SENP7 0.48 4.96 0.41 2.3e-6 Colorectal cancer; TGCT cis rs736801 0.521 rs41525648 chr5:131827775 A/G cg02551604 chr5:131831745 NA 0.76 8.45 0.6 6.53e-14 Breast cancer;Mosquito bite size; TGCT cis rs12477438 0.765 rs4374423 chr2:99662348 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs8180040 0.620 rs9875235 chr3:47083621 G/A cg27129171 chr3:47204927 SETD2 0.71 8.51 0.61 4.8e-14 Colorectal cancer; TGCT cis rs2204008 0.683 rs11519834 chr12:38053575 T/A cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs6701037 0.566 rs4344281 chr1:175135376 C/T cg08873628 chr1:175162347 KIAA0040 0.47 4.57 0.38 1.18e-5 Alcohol dependence; TGCT cis rs3892630 0.588 rs7260037 chr19:33242701 G/A cg22980127 chr19:33182716 NUDT19 0.74 6.09 0.48 1.3e-8 Red blood cell traits; TGCT cis rs7772486 0.686 rs4896828 chr6:145953339 A/C cg13319975 chr6:146136371 FBXO30 -0.52 -4.78 -0.39 4.81e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs2075371 0.933 rs1421480 chr7:133958114 A/C cg11752832 chr7:134001865 SLC35B4 0.68 5.89 0.47 3.32e-8 Mean platelet volume; TGCT cis rs7937682 0.924 rs6589244 chr11:111534333 T/C cg09085632 chr11:111637200 PPP2R1B -1.07 -10.2 -0.68 4.05e-18 Primary sclerosing cholangitis; TGCT cis rs9677476 0.516 rs6707708 chr2:232020821 T/C cg07929768 chr2:232055508 NA 0.33 5.21 0.42 7.7300000000000005e-07 Food antigen IgG levels; TGCT trans rs7618501 0.633 rs11130234 chr3:50024758 G/T cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.38 0.64 3.95e-16 Intelligence (multi-trait analysis); TGCT cis rs9467711 0.606 rs1977 chr6:26377546 A/G cg10795676 chr6:26370623 BTN3A2 -0.45 -4.91 -0.4 2.76e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs7552404 0.924 rs2153126 chr1:76199345 C/G cg10523679 chr1:76189770 ACADM 0.89 9.88 0.66 2.42e-17 Blood metabolite levels;Acylcarnitine levels; TGCT trans rs459571 0.920 rs455073 chr9:136909141 G/C cg09836344 chr4:1243392 C4orf42;CTBP1 -0.73 -7.93 -0.58 1.11e-12 Platelet distribution width; TGCT cis rs6460942 0.908 rs112897715 chr7:12241541 T/C cg06484146 chr7:12443880 VWDE -0.54 -4.76 -0.39 5.21e-6 Coronary artery disease; TGCT cis rs3101457 0.515 rs4658628 chr1:244516090 T/C cg09033006 chr1:244517177 C1orf100 -0.41 -4.47 -0.37 1.73e-5 Smoking behavior; TGCT cis rs12580194 1.000 rs7308316 chr12:55709162 T/A cg20672549 chr12:56432144 IKZF4 0.26 4.71 0.39 6.51e-6 Cancer; TGCT cis rs739496 0.895 rs2073950 chr12:111894072 C/T cg10833066 chr12:111807467 FAM109A 0.36 5.1 0.42 1.26e-6 Platelet count; TGCT cis rs2243480 1.000 rs383402 chr7:65586653 A/C cg20637647 chr7:64974828 NA -0.88 -5.12 -0.42 1.13e-6 Diabetic kidney disease; TGCT cis rs4629710 0.592 rs13195700 chr6:131585299 C/T cg12606694 chr6:131520996 AKAP7 0.38 4.5 0.37 1.56e-5 Multiple myeloma (IgH translocation); TGCT cis rs7267979 0.966 rs3002698 chr20:25303379 C/G cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3796619 0.503 rs13147452 chr4:1078124 G/A cg27284194 chr4:1044797 NA 0.71 8.07 0.59 5.03e-13 Recombination rate (males); TGCT cis rs77372450 0.551 rs11739924 chr5:157070236 C/A cg19063654 chr5:156516798 HAVCR2 -0.37 -4.43 -0.37 2.01e-5 Bipolar disorder (body mass index interaction); TGCT cis rs60154123 0.730 rs12403947 chr1:210456524 A/G cg22029157 chr1:209979665 IRF6 -0.68 -5.15 -0.42 9.98e-7 Coronary artery disease; TGCT cis rs2013441 0.932 rs2526479 chr17:20130221 T/G cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs10875746 0.903 rs12315625 chr12:48472453 G/A cg20731937 chr12:48336164 NA 0.62 4.95 0.41 2.36e-6 Longevity (90 years and older); TGCT cis rs12477438 1.000 rs17760953 chr2:99859863 G/A cg14399236 chr2:99771627 LIPT1;TSGA10 -0.81 -6.36 -0.5 3.59e-9 Chronic sinus infection; TGCT cis rs9814567 1.000 rs7426847 chr3:134267519 A/G cg06109529 chr3:134205091 CEP63;ANAPC13 0.96 9.11 0.63 1.79e-15 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.06 -9.57 -0.65 1.41e-16 Platelet count; TGCT cis rs9457247 1.000 rs2149090 chr6:167372764 T/C cg23791538 chr6:167370224 RNASET2 0.51 5.12 0.42 1.12e-6 Crohn's disease; TGCT cis rs6964587 1.000 rs28584017 chr7:91719168 G/A cg22709100 chr7:91322751 NA 0.29 4.8 0.4 4.45e-6 Breast cancer; TGCT cis rs9916302 0.904 rs679995 chr17:37441679 A/T cg15445000 chr17:37608096 MED1 -0.33 -4.93 -0.4 2.59e-6 Glomerular filtration rate (creatinine); TGCT cis rs3784262 0.565 rs34676542 chr15:58318716 C/T cg12031962 chr15:58353849 ALDH1A2 -0.39 -5.63 -0.45 1.16e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs2243480 0.708 rs781141 chr7:65438553 A/G cg07424592 chr7:64974309 NA 1.33 7.68 0.57 4.1e-12 Diabetic kidney disease; TGCT cis rs10504229 0.683 rs17194487 chr8:58104912 C/T cg21724239 chr8:58056113 NA 0.49 5.8 0.46 5.29e-8 Developmental language disorder (linguistic errors); TGCT cis rs12477438 1.000 rs6542873 chr2:99824965 C/T cg14399236 chr2:99771627 LIPT1;TSGA10 -0.73 -6.24 -0.49 6.35e-9 Chronic sinus infection; TGCT cis rs11690935 0.802 rs34636594 chr2:172911094 A/G cg13550731 chr2:172543902 DYNC1I2 -1.12 -11.05 -0.7 3.57e-20 Schizophrenia; TGCT cis rs2032447 0.714 rs199736 chr6:25936787 C/T cg12310025 chr6:25882481 NA -0.63 -5.71 -0.46 7.79e-8 Intelligence (multi-trait analysis); TGCT cis rs11031096 0.678 rs11031219 chr11:4197578 G/A cg18678763 chr11:4115507 RRM1 -0.46 -6.03 -0.48 1.78e-8 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs7666738 0.819 rs13120307 chr4:99036100 A/C cg05340658 chr4:99064831 C4orf37 0.51 5.69 0.45 8.74e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs763121 0.853 rs5757211 chr22:39051705 C/T cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs6725041 0.547 rs61696052 chr2:213201295 G/C cg16329650 chr2:213403929 ERBB4 -0.67 -5.86 -0.47 3.89e-8 QT interval (ambient particulate matter interaction); TGCT cis rs7611238 0.560 rs4677838 chr3:195105419 G/A cg27323046 chr3:195102265 ACAP2 0.39 5.09 0.42 1.29e-6 Body mass index; TGCT cis rs10256972 0.721 rs4720249 chr7:1072563 C/G cg03188948 chr7:1209495 NA 0.45 5.85 0.47 4.04e-8 Longevity;Endometriosis; TGCT cis rs6992820 0.899 rs7013301 chr8:56688226 G/T cg06880721 chr8:56792545 LYN -0.53 -4.51 -0.38 1.5e-5 Mean platelet volume; TGCT cis rs4523957 0.614 rs7220685 chr17:2059385 A/G cg16513277 chr17:2031491 SMG6 -0.2 -4.64 -0.38 8.83e-6 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs9513627 0.573 rs12431100 chr13:100184918 C/G cg25919922 chr13:100150906 NA -0.86 -5.48 -0.44 2.32e-7 Obesity-related traits; TGCT cis rs6570726 0.846 rs9376954 chr6:145943737 T/A cg13319975 chr6:146136371 FBXO30 -0.5 -4.49 -0.37 1.63e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs7698623 0.702 rs1599722 chr4:88782786 A/G cg02735620 chr4:88950514 PKD2 -0.44 -4.81 -0.4 4.22e-6 Cardiovascular disease risk factors; TGCT cis rs13242816 1.000 rs34678019 chr7:116189490 A/G cg16553024 chr7:116138462 CAV2 -0.44 -5.26 -0.43 6.11e-7 P wave duration; TGCT cis rs739496 1.000 rs7296313 chr12:111878526 T/C cg10833066 chr12:111807467 FAM109A 0.37 5.63 0.45 1.14e-7 Platelet count; TGCT cis rs13256369 0.802 rs11249884 chr8:8561552 C/T cg18904891 chr8:8559673 CLDN23 -0.56 -5.23 -0.43 6.88e-7 Obesity-related traits; TGCT cis rs4665809 1.000 rs4665823 chr2:26312723 A/G cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs2239547 0.522 rs9844736 chr3:52931971 T/G cg10802521 chr3:52805072 NEK4 0.63 5.9 0.47 3.26e-8 Schizophrenia; TGCT cis rs7811142 0.945 rs6978739 chr7:100098680 C/G cg18515655 chr7:100026757 MEPCE;ZCWPW1 -1.05 -9.12 -0.63 1.65e-15 Platelet count; TGCT cis rs736408 0.677 rs2286798 chr3:52821177 G/T cg10802521 chr3:52805072 NEK4 0.75 9.1 0.63 1.85e-15 Bipolar disorder; TGCT cis rs2153535 0.563 rs6942177 chr6:8534460 A/G cg23788917 chr6:8435910 SLC35B3 -0.63 -5.75 -0.46 6.55e-8 Motion sickness; TGCT cis rs1691799 0.799 rs10784525 chr12:66772766 G/A cg16791601 chr12:66731901 HELB -0.25 -5.2 -0.42 8.12e-7 White blood cell count (basophil); TGCT cis rs3771570 1.000 rs17386695 chr2:242379751 A/G cg21155796 chr2:242212141 HDLBP -0.93 -6.69 -0.51 6.94e-10 Prostate cancer; TGCT cis rs3087591 0.960 rs12943508 chr17:29599954 C/G cg24425628 chr17:29625626 OMG;NF1 0.48 7.43 0.56 1.52e-11 Hip circumference; TGCT cis rs4786125 0.596 rs12149100 chr16:6922512 T/G cg03623568 chr16:6915990 A2BP1 -0.45 -6.77 -0.52 4.65e-10 Heart rate variability traits (SDNN); TGCT cis rs12220898 0.749 rs11101075 chr10:50485110 G/T cg06072769 chr10:50146962 WDFY4 0.38 5.07 0.41 1.38e-6 Inflammatory biomarkers; TGCT cis rs9788721 0.836 rs17484524 chr15:78772676 A/G cg18825076 chr15:78729989 IREB2 -0.34 -5.11 -0.42 1.18e-6 Post bronchodilator FEV1;Post bronchodilator FEV1/FVC ratio;Emphysema imaging phenotypes;Emphysema distribution in smoking;Local histogram emphysema pattern;Post bronchodilator FEV1/FVC ratio in COPD; TGCT cis rs2739330 0.703 rs5760112 chr22:24259772 C/G cg12419862 chr22:24373484 LOC391322 -0.87 -9.92 -0.67 1.99e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs910316 1.000 rs4903279 chr14:75546583 C/T cg23033748 chr14:75592666 NEK9 0.28 4.68 0.39 7.29e-6 Height; TGCT cis rs4975709 0.801 rs3797063 chr5:1881549 A/T cg14773178 chr5:1868261 NA 0.36 4.88 0.4 3.23e-6 Cardiovascular disease risk factors; TGCT cis rs5760092 0.627 rs6519489 chr22:24261846 G/A cg04234412 chr22:24373322 LOC391322 0.93 8.57 0.61 3.38e-14 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs2836974 0.644 rs11088472 chr21:40699376 A/C cg06238570 chr21:40685208 BRWD1 -0.82 -8.76 -0.62 1.22e-14 Cognitive function; TGCT cis rs3026101 0.671 rs1065482 chr17:5284719 T/C cg25236894 chr17:5323110 RPAIN;NUP88 0.48 4.68 0.39 7.51e-6 Body mass index; TGCT cis rs13191362 0.507 rs7772787 chr6:163190981 C/T cg21926612 chr6:163149169 PACRG;PARK2 0.51 4.45 0.37 1.9e-5 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs6141769 0.542 rs2064933 chr20:31314625 A/G cg13636640 chr20:31349939 DNMT3B -0.52 -4.54 -0.38 1.34e-5 Subjective well-being; TGCT cis rs8180040 0.966 rs17476234 chr3:47326298 G/A cg27129171 chr3:47204927 SETD2 -0.7 -8.64 -0.61 2.35e-14 Colorectal cancer; TGCT cis rs3749237 0.595 rs3924462 chr3:49524236 T/G cg03060546 chr3:49711283 APEH 0.76 8.69 0.62 1.77e-14 Resting heart rate; TGCT cis rs12711979 0.509 rs12711972 chr2:3823786 T/C cg17052675 chr2:3827356 NA -0.55 -12.73 -0.75 2.94e-24 Itch intensity from mosquito bite adjusted by bite size; TGCT cis rs7027203 0.595 rs2398876 chr9:96536853 T/C cg13679303 chr9:96623674 NA 0.52 7.49 0.56 1.12e-11 DNA methylation (variation); TGCT cis rs9486719 1.000 rs4343922 chr6:96876903 C/T cg06623918 chr6:96969491 KIAA0776 0.97 9.2 0.64 1.06e-15 Migraine;Coronary artery disease; TGCT cis rs6500602 0.702 rs3789038 chr16:4546586 C/G cg08645402 chr16:4508243 NA -0.2 -4.89 -0.4 3.12e-6 Schizophrenia; TGCT cis rs28386778 0.863 rs9207 chr17:61823899 C/T cg06873352 chr17:61820015 STRADA 0.55 6.13 0.48 1.09e-8 Prudent dietary pattern; TGCT cis rs28386778 0.897 rs8067102 chr17:61848779 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs7714584 1.000 rs1896709 chr5:150245032 A/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs2228479 0.867 rs17784386 chr16:89947457 A/G cg04013166 chr16:89971882 TCF25 0.32 4.46 0.37 1.84e-5 Skin colour saturation; TGCT cis rs7226408 0.948 rs11661681 chr18:34395540 A/G cg06757138 chr18:34340585 FHOD3 -0.25 -4.55 -0.38 1.25e-5 Obesity-related traits; TGCT cis rs6121246 0.567 rs6060260 chr20:30192907 C/T cg21427119 chr20:30132790 HM13 -0.42 -6.17 -0.48 8.75e-9 Mean corpuscular hemoglobin; TGCT cis rs3820928 1.000 rs4675116 chr2:227769607 A/C cg11843606 chr2:227700838 RHBDD1 -0.51 -4.5 -0.37 1.52e-5 Pulmonary function; TGCT cis rs3847687 1.000 rs34853396 chr12:131519265 G/T cg25772418 chr12:131519998 GPR133 -0.34 -6.26 -0.49 5.81e-9 Longevity; TGCT cis rs68170813 0.559 rs12537733 chr7:106965447 A/T cg02696742 chr7:106810147 HBP1 -0.7 -5.85 -0.47 4.03e-8 Coronary artery disease; TGCT cis rs7666738 0.830 rs10031751 chr4:98939134 G/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs7402982 0.934 rs6598539 chr15:99204483 T/C cg03437748 chr15:99193247 IGF1R 0.55 5.9 0.47 3.21e-8 Birth weight; TGCT cis rs8037137 1.000 rs1105291 chr15:91502383 C/T cg22570213 chr15:91497863 RCCD1 0.53 4.88 0.4 3.18e-6 Platelet count;Serous invasive ovarian cancer;High-grade serous ovarian cancer;Invasive epithelial ovarian cancer; TGCT cis rs137699 0.687 rs4821887 chr22:39756985 C/T cg05872129 chr22:39784769 NA -0.71 -6.06 -0.48 1.51e-8 IgG glycosylation; TGCT cis rs2456568 0.835 rs1518578 chr11:93656854 G/T cg26875233 chr11:93583750 C11orf90 -0.5 -6.3 -0.49 4.79e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs4689388 0.609 rs4234729 chr4:6286087 T/C cg14416269 chr4:6271139 WFS1 0.47 5.65 0.45 1.07e-7 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs2594989 0.733 rs2447605 chr3:11574296 C/G cg00170343 chr3:11313890 ATG7 -0.64 -4.85 -0.4 3.63e-6 Circulating chemerin levels; TGCT cis rs9467711 0.606 rs9366655 chr6:26377385 C/G cg16898833 chr6:26189333 HIST1H4D 1.09 5.27 0.43 5.92e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs10504229 1.000 rs17805602 chr8:58179915 A/G cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6542838 0.698 rs6732017 chr2:99434381 T/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.49 -4.71 -0.39 6.49e-6 Fear of minor pain; TGCT cis rs8051431 1.000 rs8051431 chr16:72015251 G/C cg06353428 chr16:71660113 MARVELD3 0.59 5.02 0.41 1.73e-6 LDL cholesterol levels; TGCT cis rs7507204 0.723 rs12610998 chr19:3413653 T/C cg08380311 chr19:3435252 NFIC 0.98 8.25 0.6 2e-13 Height; TGCT cis rs514406 0.683 rs6588440 chr1:53209587 C/T cg08859206 chr1:53392774 SCP2 0.36 5.11 0.42 1.2e-6 Monocyte count; TGCT cis rs807669 0.868 rs2800973 chr22:19168616 A/G cg02655711 chr22:19163373 SLC25A1 0.42 9.86 0.66 2.71e-17 Metabolite levels; TGCT cis rs7647973 1.000 rs56127630 chr3:49438036 C/G cg06212747 chr3:49208901 KLHDC8B -0.59 -4.72 -0.39 6.19e-6 Menarche (age at onset); TGCT cis rs2439831 0.850 rs9944216 chr15:44160773 C/G cg27015174 chr15:43622946 ADAL;LCMT2 -0.74 -4.48 -0.37 1.68e-5 Lung cancer in ever smokers; TGCT cis rs514406 0.861 rs4926577 chr1:53226788 C/A cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.42e-13 Monocyte count; TGCT cis rs7086627 0.515 rs4934189 chr10:82214792 C/T cg00277334 chr10:82204260 NA -0.56 -9.04 -0.63 2.62e-15 Post bronchodilator FEV1; TGCT cis rs17270561 0.578 rs76182885 chr6:25904085 G/C cg17042849 chr6:26104293 HIST1H4C -0.79 -5.76 -0.46 6.33e-8 Iron status biomarkers; TGCT cis rs514406 0.570 rs1332776 chr1:53189816 C/T cg16325326 chr1:53192061 ZYG11B 0.8 11.61 0.72 1.54e-21 Monocyte count; TGCT cis rs6988636 1.000 rs28542077 chr8:124190896 T/C cg22384356 chr8:124195192 FAM83A -0.42 -5.54 -0.45 1.74e-7 Urinary uromodulin levels; TGCT cis rs6582630 0.555 rs11182148 chr12:38464883 A/C cg26384229 chr12:38710491 ALG10B 0.82 7.5 0.56 1.07e-11 Drug-induced liver injury (flucloxacillin); TGCT cis rs3820068 0.608 rs7552400 chr1:16035892 A/G cg17385448 chr1:15911702 AGMAT 0.35 4.99 0.41 1.96e-6 Systolic blood pressure; TGCT cis rs2153535 0.580 rs9393016 chr6:8458573 T/A cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs3099143 1.000 rs3102709 chr15:77072260 C/T cg21673338 chr15:77095150 SCAPER -0.51 -5.12 -0.42 1.11e-6 Recalcitrant atopic dermatitis; TGCT cis rs7267979 0.966 rs2261790 chr20:25262789 T/C cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12210905 0.920 rs72839453 chr6:27265761 A/G cg08851530 chr6:28072375 NA 1.29 5.45 0.44 2.65e-7 Hip circumference adjusted for BMI; TGCT cis rs68092024 0.731 rs793480 chr3:99488364 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.5 5.94 0.47 2.64e-8 Cleft lip with or without cleft palate; TGCT cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg02579736 chr3:10068473 FANCD2;CIDECP 0.84 5.71 0.46 8.05e-8 Alzheimer's disease; TGCT cis rs2806561 0.695 rs66592286 chr1:23333649 G/C cg12483005 chr1:23474871 LUZP1 0.37 4.72 0.39 6.21e-6 Height; TGCT cis rs1862618 0.853 rs2113079 chr5:56157951 A/G cg12311346 chr5:56204834 C5orf35 -0.67 -6.68 -0.51 7.25e-10 Initial pursuit acceleration; TGCT cis rs950027 0.620 rs1719246 chr15:45625479 T/A cg26924012 chr15:45694286 SPATA5L1 0.8 8.99 0.63 3.48e-15 Response to fenofibrate (adiponectin levels); TGCT trans rs208520 1.000 rs208521 chr6:66953625 C/T cg15611600 chr13:45563400 KIAA1704;NUFIP1 -0.88 -8.21 -0.59 2.37e-13 Exhaled nitric oxide output; TGCT cis rs9916302 0.904 rs2338798 chr17:37547269 T/C cg07936489 chr17:37558343 FBXL20 0.64 4.94 0.41 2.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs7666738 0.512 rs1648536 chr4:99019881 G/T cg05340658 chr4:99064831 C4orf37 -0.41 -4.99 -0.41 1.95e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs713587 1.000 rs2384054 chr2:25156773 T/C cg01884057 chr2:25150051 NA 0.39 8.05 0.59 5.76e-13 Body mass index in non-asthmatics; TGCT cis rs9303401 0.659 rs34170300 chr17:56789905 G/C cg10487724 chr17:56770010 TEX14;RAD51C 0.67 6.3 0.49 4.7e-9 Cognitive test performance; TGCT cis rs1568889 1.000 rs66857704 chr11:28212346 A/G cg06544937 chr11:28130018 METT5D1;KIF18A 0.82 8.31 0.6 1.42e-13 Bipolar disorder; TGCT cis rs55823223 0.564 rs4572466 chr17:73846314 A/C cg10935138 chr17:73851978 WBP2 0.82 7.57 0.56 7.35e-12 Psoriasis; TGCT cis rs231513 0.954 rs231512 chr17:41965831 G/A cg26893861 chr17:41843967 DUSP3 -0.75 -5.33 -0.43 4.48e-7 Cognitive function; TGCT trans rs9929218 0.551 rs2281850 chr16:68718750 C/T cg04657470 chr2:198365150 HSPE1;HSPD1 -0.62 -8.17 -0.59 3.03e-13 Colorectal cancer; TGCT cis rs903263 1.000 rs12565896 chr1:84636803 T/G cg09664975 chr1:84543551 PRKACB 0.47 4.48 0.37 1.65e-5 Breast cancer (male); TGCT cis rs2836974 0.602 rs2037925 chr21:40699931 C/T cg11644478 chr21:40555479 PSMG1 -0.53 -4.55 -0.38 1.28e-5 Cognitive function; TGCT cis rs6089829 0.962 rs2314130 chr20:61665129 G/T cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs11190604 0.767 rs10883485 chr10:102174805 G/C cg16005271 chr10:102321736 NA 0.45 4.57 0.38 1.15e-5 Palmitoleic acid (16:1n-7) levels; TGCT trans rs6089829 0.925 rs2277767 chr20:61666937 G/A cg23505145 chr19:12996616 KLF1 0.79 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs9976767 0.608 rs11909987 chr21:43822402 C/A cg23042151 chr21:43824109 UBASH3A -0.23 -5.03 -0.41 1.65e-6 Type 1 diabetes; TGCT cis rs881375 0.967 rs7848332 chr9:123669496 T/C cg09419670 chr9:123605666 PSMD5;LOC253039 0.46 5.06 0.41 1.49e-6 Rheumatoid arthritis; TGCT cis rs7714584 1.000 rs7709388 chr5:150246539 C/G cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs28386778 0.863 rs4968661 chr17:61796306 A/G cg01411255 chr17:61851458 DDX42;CCDC47 0.77 7.49 0.56 1.15e-11 Prudent dietary pattern; TGCT cis rs9611519 1.000 rs5758264 chr22:41616284 T/G cg13695892 chr22:41940480 POLR3H -0.51 -4.71 -0.39 6.49e-6 Neuroticism; TGCT cis rs8054556 0.716 rs11642933 chr16:29946708 G/A cg26859862 chr16:30389551 SEPT1 -0.53 -4.54 -0.38 1.31e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs9368481 0.594 rs2636425 chr6:26799460 A/G cg18867708 chr6:26865862 GUSBL1 0.4 5.17 0.42 8.99e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs2180341 1.000 rs4897207 chr6:127605898 C/T cg27446573 chr6:127587934 RNF146 1.13 10.12 0.67 6.64e-18 Breast cancer; TGCT cis rs7914558 0.966 rs10883805 chr10:104708251 T/C cg04362960 chr10:104952993 NT5C2 0.58 5.15 0.42 9.77e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs10782582 0.586 rs112368938 chr1:76336339 C/T cg03433033 chr1:76189801 ACADM -0.5 -4.98 -0.41 2.11e-6 Daytime sleep phenotypes; TGCT cis rs7246657 0.943 rs10407084 chr19:37907792 T/C cg18154014 chr19:37997991 ZNF793 0.95 6.52 0.51 1.58e-9 Coronary artery calcification; TGCT cis rs1153858 0.945 rs1974981 chr15:45729123 C/T cg14582100 chr15:45693742 SPATA5L1 -0.41 -4.74 -0.39 5.78e-6 Homoarginine levels; TGCT cis rs4665809 0.878 rs4665826 chr2:26367503 A/T cg25036284 chr2:26402008 FAM59B 0.55 4.71 0.39 6.45e-6 Gut microbiome composition (summer); TGCT cis rs2458413 1.000 rs2458414 chr8:105355840 A/G cg23108931 chr8:105342351 NA 0.36 6.01 0.48 1.91e-8 Paget's disease; TGCT cis rs1865760 1.000 rs9358895 chr6:25924655 C/T cg16482183 chr6:26056742 HIST1H1C 0.51 4.59 0.38 1.06e-5 Height; TGCT cis rs2688482 0.512 rs1106502 chr3:195517258 G/A cg13752114 chr3:195489708 MUC4 0.32 4.72 0.39 6.34e-6 Lung disease severity in cystic fibrosis; TGCT cis rs12220238 0.841 rs11000942 chr10:76025256 G/A cg19889307 chr10:75911429 ADK;AP3M1 0.84 6.02 0.48 1.87e-8 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs9942416 0.660 rs4704234 chr5:75001432 A/G cg19683494 chr5:74908142 NA 0.62 6.43 0.5 2.51e-9 Age-related disease endophenotypes; TGCT trans rs1005277 0.579 rs1780116 chr10:38526621 C/T cg17830980 chr10:43048298 ZNF37B -0.83 -10.39 -0.68 1.4e-18 Extrinsic epigenetic age acceleration; TGCT cis rs71636778 0.509 rs56139710 chr1:27269788 C/T cg23921621 chr1:27994728 IFI6 -0.43 -4.61 -0.38 9.92e-6 Monocyte percentage of white cells;Granulocyte percentage of myeloid white cells; TGCT cis rs62244186 0.632 rs1402751 chr3:44594030 C/A cg15687855 chr3:44754131 ZNF502 -0.45 -5.35 -0.43 4.04e-7 Depressive symptoms; TGCT cis rs7507204 0.906 rs62125968 chr19:3422261 G/A cg08380311 chr19:3435252 NFIC 0.94 7.98 0.58 8.23e-13 Height; TGCT cis rs7617773 0.817 rs6806112 chr3:48276077 A/T cg11946769 chr3:48343235 NME6 0.75 7.14 0.54 7.06e-11 Coronary artery disease; TGCT cis rs950169 0.656 rs748455 chr15:85149575 T/C cg12863693 chr15:85201151 NMB 0.41 4.88 0.4 3.26e-6 Schizophrenia; TGCT cis rs7647973 0.710 rs2029591 chr3:49646981 C/T cg05785598 chr3:49045655 WDR6 -0.41 -4.74 -0.39 5.72e-6 Menarche (age at onset); TGCT cis rs3784262 0.565 rs9635350 chr15:58298412 G/A cg12031962 chr15:58353849 ALDH1A2 0.38 5.53 0.44 1.82e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs6121246 0.909 rs6060633 chr20:30263317 G/T cg13852791 chr20:30311386 BCL2L1 0.78 5.8 0.46 5.15e-8 Mean corpuscular hemoglobin; TGCT cis rs7618915 0.501 rs1866268 chr3:52719398 C/A cg05573699 chr3:52720067 GNL3;PBRM1 -0.51 -4.82 -0.4 4.16e-6 Bipolar disorder; TGCT cis rs896854 0.552 rs2515236 chr8:95934907 A/G cg23172400 chr8:95962367 TP53INP1 0.32 4.81 0.4 4.29e-6 Type 2 diabetes; TGCT cis rs4499344 0.589 rs259233 chr19:33127000 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.83 8.3 0.6 1.52e-13 Mean platelet volume; TGCT cis rs7412746 0.658 rs12405726 chr1:150956128 G/A cg09365446 chr1:150670422 GOLPH3L 0.36 5.0 0.41 1.9e-6 Melanoma; TGCT cis rs4253772 0.550 rs6008598 chr22:46704243 C/T cg24881330 chr22:46731750 TRMU 1.05 5.41 0.44 3.15e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs10256972 0.577 rs2949179 chr7:1209885 C/G cg03188948 chr7:1209495 NA 0.5 7.0 0.53 1.44e-10 Longevity;Endometriosis; TGCT cis rs6545883 0.899 rs12473030 chr2:61720497 T/A cg15711740 chr2:61764176 XPO1 -0.54 -4.95 -0.41 2.39e-6 Tuberculosis; TGCT cis rs1862618 0.620 rs2591967 chr5:56233551 C/G cg24531977 chr5:56204891 C5orf35 0.68 7.22 0.54 4.69e-11 Initial pursuit acceleration; TGCT cis rs1670533 1.000 rs6852155 chr4:1067638 T/G cg27284194 chr4:1044797 NA 0.68 5.86 0.47 4e-8 Recombination rate (females); TGCT cis rs7666738 0.830 rs113999196 chr4:99041961 C/T cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs7819412 0.522 rs13276708 chr8:10989206 T/C cg21775007 chr8:11205619 TDH -0.6 -5.27 -0.43 5.9e-7 Triglycerides; TGCT cis rs6866344 0.568 rs10516147 chr5:178094484 A/G cg10224037 chr5:178157518 ZNF354A 0.59 5.06 0.41 1.46e-6 Neutrophil percentage of white cells; TGCT cis rs7617480 0.648 rs4974088 chr3:48898749 T/C cg07636037 chr3:49044803 WDR6 0.79 6.43 0.5 2.54e-9 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs1552244 0.808 rs17032306 chr3:10091399 C/G cg02579736 chr3:10068473 FANCD2;CIDECP 0.91 5.86 0.47 3.96e-8 Alzheimer's disease; TGCT cis rs28386778 0.897 rs716880 chr17:61902822 C/G cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.7 -0.39 6.79e-6 Prudent dietary pattern; TGCT cis rs6750047 0.585 rs168054 chr2:38260282 C/G cg07380506 chr2:38303506 CYP1B1 -0.56 -5.21 -0.42 7.68e-7 Cutaneous malignant melanoma;Melanoma; TGCT cis rs2075371 0.865 rs2544172 chr7:133931338 T/C cg11752832 chr7:134001865 SLC35B4 0.68 5.89 0.47 3.42e-8 Mean platelet volume; TGCT cis rs2469997 0.800 rs2447177 chr8:120356431 A/G cg02248809 chr8:120845432 TAF2 0.58 4.47 0.37 1.76e-5 Hypertension (SNP x SNP interaction); TGCT cis rs4975709 0.544 rs4975748 chr5:1866025 G/A cg14773178 chr5:1868261 NA 0.35 6.18 0.49 8.45e-9 Cardiovascular disease risk factors; TGCT cis rs10504229 0.683 rs2318143 chr8:58114660 C/T cg08280861 chr8:58055591 NA 0.4 4.56 0.38 1.22e-5 Developmental language disorder (linguistic errors); TGCT trans rs3780486 0.846 rs3780490 chr9:33129839 A/G cg04842962 chr6:43655489 MRPS18A 1.24 15.83 0.82 1.46e-31 IgG glycosylation; TGCT cis rs6912958 0.559 rs242281 chr6:88048916 A/C cg12350822 chr6:88032061 C6orf162;GJB7 0.47 6.29 0.49 5.04e-9 Monocyte percentage of white cells; TGCT cis rs2274273 0.743 rs7161656 chr14:55524530 A/G cg01923255 chr14:55878535 KIAA0831 0.56 4.76 0.39 5.24e-6 Protein biomarker; TGCT cis rs6088580 0.634 rs6059829 chr20:33017074 G/A cg08999081 chr20:33150536 PIGU 0.29 5.66 0.45 9.92e-8 Glomerular filtration rate (creatinine); TGCT cis rs28386778 0.933 rs2665804 chr17:61951836 G/T cg23090583 chr17:61904693 PSMC5;FTSJ3 1.09 15.63 0.81 4.21e-31 Prudent dietary pattern; TGCT cis rs2842992 1.000 rs2758322 chr6:160075188 G/T cg11366901 chr6:160182831 ACAT2 0.92 6.26 0.49 5.77e-9 Age-related macular degeneration (geographic atrophy); TGCT cis rs9430161 0.579 rs11121667 chr1:11038476 C/T cg27631724 chr1:11040367 C1orf127 0.55 6.55 0.51 1.39e-9 Ewing sarcoma; TGCT cis rs12142240 0.698 rs6683192 chr1:46830257 C/T cg00530320 chr1:46809349 NSUN4 0.29 6.03 0.48 1.71e-8 Menopause (age at onset); TGCT cis rs2404602 0.647 rs35710279 chr15:77082234 T/A cg22467129 chr15:76604101 ETFA 0.47 4.62 0.38 9.31e-6 Blood metabolite levels; TGCT cis rs4409675 0.576 rs6691656 chr1:28221130 C/G cg23691781 chr1:28212827 C1orf38 0.26 5.32 0.43 4.68e-7 Corneal astigmatism; TGCT cis rs3796352 1.000 rs13058817 chr3:53024139 C/T cg07884673 chr3:53033167 SFMBT1 0.64 6.39 0.5 3.03e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs9818758 0.607 rs9862483 chr3:49195441 G/A cg07636037 chr3:49044803 WDR6 -1.04 -5.13 -0.42 1.09e-6 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs7301826 0.651 rs7956851 chr12:131319099 C/T cg15791944 chr12:131647654 NA 0.23 4.64 0.38 8.68e-6 Plasma plasminogen activator levels; TGCT cis rs9325144 0.560 rs10506125 chr12:39120287 C/T cg13010199 chr12:38710504 ALG10B 0.61 5.7 0.46 8.26e-8 Morning vs. evening chronotype; TGCT cis rs1568889 1.000 rs61889054 chr11:28333000 A/C cg06544937 chr11:28130018 METT5D1;KIF18A 0.75 6.72 0.52 5.95e-10 Bipolar disorder; TGCT cis rs11971779 0.938 rs11981688 chr7:139088895 A/G cg07862535 chr7:139043722 LUC7L2 0.79 5.8 0.46 5.13e-8 Diisocyanate-induced asthma; TGCT cis rs9682041 0.673 rs1511175 chr3:170076006 C/G cg11886554 chr3:170076028 SKIL 0.84 5.65 0.45 1.05e-7 Glomerular filtration rate in non diabetics (creatinine);Glomerular filtration rate (creatinine); TGCT cis rs7226408 0.857 rs72892518 chr18:34665420 G/A cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs514406 0.607 rs6696940 chr1:53203427 C/T cg08859206 chr1:53392774 SCP2 0.36 5.1 0.42 1.22e-6 Monocyte count; TGCT cis rs8062405 0.573 rs6565300 chr16:28993049 G/T cg01117621 chr16:28073818 GSG1L 0.36 4.69 0.39 7.21e-6 Cognitive ability (multi-trait analysis);Cognitive ability; TGCT cis rs614226 0.935 rs17431717 chr12:120912210 G/A cg10072921 chr12:121022843 NA 0.46 4.98 0.41 2.11e-6 Type 1 diabetes nephropathy; TGCT cis rs6663390 0.510 rs73072979 chr1:208072057 G/A cg03990033 chr1:208084030 CD34 0.73 6.45 0.5 2.32e-9 Facial morphology (factor 18); TGCT cis rs11711311 1.000 rs1073040 chr3:113522123 C/G cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.69 -6.4 -0.5 2.84e-9 IgG glycosylation; TGCT cis rs12497850 0.931 rs7627404 chr3:48819668 A/C cg07636037 chr3:49044803 WDR6 0.94 10.39 0.68 1.46e-18 Parkinson's disease; TGCT cis rs4665809 1.000 rs6729080 chr2:26301282 G/A cg25036284 chr2:26402008 FAM59B -0.57 -4.97 -0.41 2.15e-6 Gut microbiome composition (summer); TGCT cis rs2115630 0.967 rs7171167 chr15:85239123 A/T cg17173187 chr15:85201210 NMB -0.4 -4.95 -0.41 2.41e-6 P wave terminal force; TGCT cis rs425277 1.000 rs262676 chr1:2078482 T/A cg03732007 chr1:2071316 PRKCZ 0.26 5.44 0.44 2.77e-7 Height; TGCT cis rs7611238 0.560 rs62287107 chr3:195052365 T/G cg27323046 chr3:195102265 ACAP2 0.36 4.9 0.4 2.94e-6 Body mass index; TGCT trans rs9951602 0.512 rs3859325 chr18:76652175 A/G cg02800362 chr5:177631904 HNRNPAB 1.14 12.9 0.76 1.17e-24 Obesity-related traits; TGCT cis rs1008375 1.000 rs555 chr4:17625658 A/G cg16339924 chr4:17578868 LAP3 0.64 5.32 0.43 4.72e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7394190 0.748 rs60212594 chr10:75414344 G/C cg07699608 chr10:75541558 CHCHD1 0.59 4.46 0.37 1.85e-5 Incident atrial fibrillation; TGCT cis rs2456568 0.867 rs7935801 chr11:93658000 G/A cg26875233 chr11:93583750 C11orf90 -0.47 -5.83 -0.46 4.5e-8 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2442825 1.000 rs2442825 chr3:9479142 G/A cg24633833 chr3:10029261 TMEM111 0.54 4.96 0.41 2.28e-6 Cerebrospinal fluid clusterin levels; TGCT cis rs514406 0.698 rs511599 chr1:53362818 T/C cg01802117 chr1:53393560 SCP2 -0.44 -5.52 -0.44 1.86e-7 Monocyte count; TGCT cis rs950169 0.922 rs11631096 chr15:85100929 G/C cg11189052 chr15:85197271 WDR73 0.84 6.67 0.51 7.68e-10 Schizophrenia; TGCT cis rs736408 0.561 rs2276815 chr3:52853747 C/G cg11645453 chr3:52864694 ITIH4 0.31 5.34 0.43 4.24e-7 Bipolar disorder; TGCT cis rs911555 0.755 rs8014800 chr14:103946302 T/C cg23461800 chr14:103021989 NA -0.35 -4.56 -0.38 1.23e-5 Intelligence (multi-trait analysis); TGCT cis rs5417 0.662 rs12601936 chr17:7172609 A/G cg25256661 chr17:7137939 DVL2 -0.64 -6.54 -0.51 1.45e-9 Diastolic blood pressure; TGCT cis rs6912958 0.712 rs6930600 chr6:88349787 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs568617 0.953 rs645900 chr11:65648135 G/A cg04055107 chr11:65626734 MUS81;CFL1 -0.57 -5.22 -0.42 7.39e-7 Crohn's disease; TGCT cis rs7666738 0.830 rs6848397 chr4:98946738 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs11190604 1.000 rs28522614 chr10:102323141 T/A cg23241863 chr10:102295624 HIF1AN 0.69 5.12 0.42 1.16e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28386778 0.829 rs1877317 chr17:61776479 T/C cg25654072 chr17:61904446 PSMC5;FTSJ3 0.56 5.18 0.42 8.87e-7 Prudent dietary pattern; TGCT cis rs682748 1.000 rs297181 chr5:17157479 A/T cg23987134 chr5:17158319 LOC285696 -0.23 -5.43 -0.44 2.9e-7 Hippocampal atrophy; TGCT cis rs710216 0.957 rs2886876 chr1:43432741 A/G cg03128534 chr1:43423976 SLC2A1 -0.62 -4.78 -0.39 4.92e-6 Red cell distribution width; TGCT cis rs6540559 1.000 rs7522250 chr1:209962539 T/C cg22029157 chr1:209979665 IRF6 0.76 6.32 0.49 4.37e-9 Cleft lip with or without cleft palate; TGCT cis rs12220238 1.000 rs10824078 chr10:75892120 C/T cg19889307 chr10:75911429 ADK;AP3M1 0.89 7.06 0.54 1.05e-10 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs651907 0.513 rs34963630 chr3:101504817 C/T cg03837452 chr3:101395095 ZBTB11;LOC100009676 0.52 4.85 0.4 3.68e-6 Colorectal cancer; TGCT cis rs17152411 1.000 rs7086447 chr10:126593553 C/A cg07906193 chr10:126599966 NA 0.42 5.28 0.43 5.6e-7 Height; TGCT cis rs28386778 0.897 rs894408 chr17:61896814 C/T cg06873352 chr17:61820015 STRADA 0.58 6.37 0.5 3.32e-9 Prudent dietary pattern; TGCT cis rs589448 0.967 rs2617834 chr12:69753365 T/C cg11871910 chr12:69753446 YEATS4 0.87 10.07 0.67 8.72e-18 Cerebrospinal fluid biomarker levels; TGCT cis rs875971 0.638 rs801205 chr7:66022144 C/A cg00343986 chr7:65444356 GUSB -0.23 -5.16 -0.42 9.66e-7 Aortic root size; TGCT cis rs9486715 0.830 rs2255552 chr6:96999643 A/G cg18709589 chr6:96969512 KIAA0776 -0.79 -7.51 -0.56 9.96e-12 Headache; TGCT trans rs7615952 0.866 rs1976459 chr3:125647486 A/T cg07211511 chr3:129823064 LOC729375 -0.47 -7.55 -0.56 8.34e-12 Blood pressure (smoking interaction); TGCT cis rs514406 0.607 rs6665324 chr1:53201610 G/A cg08859206 chr1:53392774 SCP2 0.34 4.9 0.4 2.91e-6 Monocyte count; TGCT cis rs12142240 0.731 rs6658556 chr1:46844180 A/C cg14993813 chr1:46806288 NSUN4 -0.59 -4.94 -0.41 2.51e-6 Menopause (age at onset); TGCT cis rs10883723 0.962 rs11191294 chr10:104225837 T/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.76 7.38 0.55 1.95e-11 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2025751 0.614 rs9370052 chr6:51638601 T/A cg20180370 chr6:50691003 TFAP2D -0.48 -4.51 -0.38 1.51e-5 Intraocular pressure; TGCT cis rs597539 0.616 rs473997 chr11:68639481 C/T cg21862992 chr11:68658383 NA 0.46 6.37 0.5 3.37e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs7618915 0.621 rs6788993 chr3:52605136 T/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.53 -5.1 -0.42 1.23e-6 Bipolar disorder; TGCT cis rs3008870 0.920 rs1925413 chr1:67417101 T/C cg11518657 chr1:67396239 MIER1 0.54 4.65 0.39 8.44e-6 Lymphocyte percentage of white cells; TGCT cis rs2739330 0.828 rs5760099 chr22:24248414 G/A cg15242686 chr22:24348715 GSTTP1 0.44 5.98 0.47 2.23e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7267979 1.000 rs6050630 chr20:25430745 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT trans rs916888 0.821 rs199525 chr17:44847834 T/G cg22968622 chr17:43663579 NA 1.24 11.44 0.72 3.96e-21 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs6952808 0.929 rs11761270 chr7:1923695 C/T cg22963979 chr7:1858916 MAD1L1 -0.36 -5.69 -0.46 8.49e-8 Bipolar disorder and schizophrenia; TGCT cis rs17102884 0.506 rs11845397 chr14:75404587 G/A cg08847533 chr14:75593920 NEK9 -0.62 -5.5 -0.44 2.09e-7 Neuroticism; TGCT cis rs12477438 0.520 rs13004491 chr2:99738008 T/C cg14399236 chr2:99771627 LIPT1;TSGA10 0.87 8.82 0.62 8.67e-15 Chronic sinus infection; TGCT cis rs1538970 0.961 rs7543428 chr1:45839643 A/G cg05343316 chr1:45956843 TESK2 0.64 5.06 0.41 1.47e-6 Platelet count; TGCT cis rs6546537 0.955 rs35947226 chr2:69845829 C/G cg10773587 chr2:69614142 GFPT1 -0.77 -6.45 -0.5 2.28e-9 Serum thyroid-stimulating hormone levels; TGCT cis rs8180040 0.593 rs4018905 chr3:47138170 A/G cg27129171 chr3:47204927 SETD2 0.7 8.55 0.61 3.75e-14 Colorectal cancer; TGCT cis rs4642101 0.694 rs12631514 chr3:12838293 G/C cg05775895 chr3:12838266 CAND2 0.91 11.19 0.71 1.61e-20 QRS complex (12-leadsum); TGCT cis rs514406 0.929 rs1242224 chr1:53314887 G/A cg24675658 chr1:53192096 ZYG11B -0.71 -8.23 -0.59 2.14e-13 Monocyte count; TGCT cis rs2997447 0.761 rs61776620 chr1:26457980 T/C cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs4919694 1.000 rs12257935 chr10:104803062 C/A cg04362960 chr10:104952993 NT5C2 1.06 7.05 0.53 1.09e-10 Arsenic metabolism; TGCT cis rs2854207 0.505 rs2466957 chr17:61961230 G/C cg23090583 chr17:61904693 PSMC5;FTSJ3 0.66 5.16 0.42 9.57e-7 Height; TGCT cis rs2468186 0.583 rs2450065 chr8:120096814 T/C cg02248809 chr8:120845432 TAF2 -0.45 -4.83 -0.4 3.99e-6 Osteoprotegerin levels; TGCT cis rs6952808 0.656 rs73048919 chr7:2103637 C/A cg04267008 chr7:1944627 MAD1L1 -0.38 -4.97 -0.41 2.16e-6 Bipolar disorder and schizophrenia; TGCT cis rs28595532 0.920 rs114382134 chr4:119733215 T/C cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs2299587 0.531 rs28839855 chr8:17855983 T/C cg01800426 chr8:17659068 MTUS1 -0.55 -4.77 -0.39 5e-6 Economic and political preferences; TGCT cis rs10214930 0.597 rs720437 chr7:27918415 C/T cg05786569 chr7:27702416 HIBADH -0.72 -5.01 -0.41 1.82e-6 Hypospadias; TGCT cis rs2067615 0.560 rs4964485 chr12:107121952 A/G cg15890332 chr12:107067104 RFX4 0.3 5.99 0.47 2.11e-8 Heart rate; TGCT cis rs28386778 0.863 rs894414 chr17:61916384 T/C cg26338869 chr17:61819248 STRADA -0.55 -5.08 -0.41 1.37e-6 Prudent dietary pattern; TGCT cis rs2717559 0.522 rs2572924 chr8:143869114 C/T cg07661805 chr8:143867942 LY6D 0.23 4.46 0.37 1.83e-5 Urinary tract infection frequency; TGCT cis rs12615966 0.789 rs1562882 chr2:105404626 G/A cg16465502 chr2:105461796 NA 0.8 5.05 0.41 1.51e-6 Pancreatic cancer; TGCT trans rs57221529 0.600 rs11750269 chr5:666270 G/A cg25482853 chr8:67687455 SGK3 1.21 10.69 0.69 2.58e-19 Lung disease severity in cystic fibrosis; TGCT cis rs10504229 0.906 rs66480865 chr8:58187100 C/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs12681287 0.547 rs66808088 chr8:87521212 C/T cg27223183 chr8:87520930 FAM82B -0.96 -7.03 -0.53 1.21e-10 Caudate activity during reward; TGCT cis rs17253792 0.731 rs28587929 chr14:56097492 C/T cg01858014 chr14:56050164 KTN1 -0.34 -4.44 -0.37 1.96e-5 Putamen volume; TGCT cis rs11640734 0.609 rs11647746 chr16:89806343 C/A cg26513180 chr16:89883248 FANCA 0.79 4.57 0.38 1.16e-5 Interleukin-17 levels; TGCT cis rs61774743 0.681 rs10749805 chr1:41850182 C/T cg01193554 chr1:41846683 NA -0.44 -5.5 -0.44 2.08e-7 Intelligence (multi-trait analysis); TGCT cis rs9467773 1.000 rs9467774 chr6:26505036 C/A cg05738196 chr6:26577821 NA 0.88 12.49 0.75 1.09e-23 Intelligence (multi-trait analysis); TGCT cis rs17401966 0.838 rs4623 chr1:10366692 C/G cg19773385 chr1:10388646 KIF1B -0.22 -4.8 -0.4 4.52e-6 Hepatocellular carcinoma; TGCT cis rs3858526 0.959 rs4559671 chr11:5923419 C/T cg13902645 chr11:5959945 NA -0.44 -4.8 -0.4 4.54e-6 DNA methylation (variation); TGCT cis rs3796352 0.527 rs11716506 chr3:52944328 C/T cg11137980 chr3:52469226 SEMA3G 0.28 4.61 0.38 9.88e-6 Immune reponse to smallpox (secreted IL-2); TGCT trans rs7824557 0.527 rs2572376 chr8:11237756 C/A cg15556689 chr8:8085844 FLJ10661 -0.75 -6.65 -0.51 8.2e-10 Retinal vascular caliber; TGCT cis rs2576037 0.583 rs593340 chr18:44418346 C/T cg23302884 chr18:44338147 ST8SIA5 -0.4 -4.61 -0.38 9.88e-6 Personality dimensions; TGCT cis rs6545883 0.894 rs2694642 chr2:61596180 A/G cg15711740 chr2:61764176 XPO1 0.54 4.66 0.39 8.14e-6 Tuberculosis; TGCT cis rs2657888 0.965 rs2657902 chr12:56933651 G/A cg23002907 chr12:56915593 RBMS2 0.44 6.15 0.48 9.65e-9 Adiponectin levels; TGCT cis rs17376456 0.825 rs28610997 chr5:93248374 T/C cg25358565 chr5:93447407 FAM172A 1.0 7.62 0.56 5.54e-12 Diabetic retinopathy; TGCT cis rs2840044 1.000 rs225259 chr17:33958168 A/G cg05299278 chr17:33885742 SLFN14 0.22 4.98 0.41 2.07e-6 Response to radiotherapy in cancer (late toxicity); TGCT cis rs9457247 0.967 rs1187532 chr6:167382020 G/A cg25258033 chr6:167368657 RNASET2 0.18 4.49 0.37 1.63e-5 Crohn's disease; TGCT cis rs9787249 0.957 rs12086750 chr1:40210468 G/C cg24920358 chr1:40204285 PPIE 0.57 10.56 0.69 5.57e-19 Blood protein levels; TGCT trans rs13064411 0.518 rs2399480 chr3:113228599 T/C cg00307254 chr3:126706825 PLXNA1 0.34 6.78 0.52 4.36e-10 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs9611519 0.542 rs8139770 chr22:41416181 C/T cg06634786 chr22:41940651 POLR3H -0.48 -4.44 -0.37 1.98e-5 Neuroticism; TGCT cis rs3784262 0.967 rs4646612 chr15:58265077 C/T cg12031962 chr15:58353849 ALDH1A2 -0.5 -7.72 -0.57 3.4e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs951366 0.789 rs823121 chr1:205724302 A/G cg07157834 chr1:205819609 PM20D1 -0.41 -6.65 -0.51 8.24e-10 Menarche (age at onset); TGCT cis rs7582180 0.652 rs11123830 chr2:100974747 A/G cg08017756 chr2:100939284 LONRF2 -0.31 -4.97 -0.41 2.2e-6 Intelligence (multi-trait analysis); TGCT cis rs6088580 0.634 rs6088484 chr20:32985961 T/C cg08999081 chr20:33150536 PIGU -0.29 -5.65 -0.45 1.02e-7 Glomerular filtration rate (creatinine); TGCT cis rs10504229 1.000 rs66477954 chr8:58187810 C/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs6752107 0.935 rs1596017 chr2:234147930 C/T cg07618928 chr2:234183455 ATG16L1;SCARNA5 0.2 4.91 0.4 2.8e-6 Crohn's disease;Inflammatory bowel disease; TGCT cis rs57590327 0.508 rs10511101 chr3:81950302 A/C cg07356753 chr3:81810745 GBE1 -0.74 -6.82 -0.52 3.5e-10 Extraversion; TGCT cis rs35264875 0.898 rs56140802 chr11:68861631 G/A cg02660097 chr11:68866761 NA 0.32 4.61 0.38 9.94e-6 Blond vs. brown hair color; TGCT cis rs12510870 0.520 rs1528924 chr4:74390976 T/C cg05868023 chr4:75230803 EREG 0.55 4.7 0.39 6.84e-6 Iris color (b* coordinate); TGCT cis rs916888 0.821 rs199505 chr17:44859410 A/G cg10780632 chr17:43973522 MAPT;LOC100128977;LOC100130148 -0.7 -4.82 -0.4 4.1e-6 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs10464366 0.614 rs62442213 chr7:39146933 C/T cg15212455 chr7:39170539 POU6F2 0.3 6.77 0.52 4.59e-10 IgG glycosylation; TGCT cis rs10504229 0.593 rs12155520 chr8:58014318 C/T cg08219700 chr8:58056026 NA 0.37 4.48 0.37 1.71e-5 Developmental language disorder (linguistic errors); TGCT cis rs270601 0.770 rs61352298 chr5:131600589 G/C cg24060327 chr5:131705240 SLC22A5 -0.66 -6.85 -0.52 3.07e-10 Acylcarnitine levels; TGCT cis rs6969780 0.722 rs3823764 chr7:27187753 C/T cg04317399 chr7:27170313 HOXA4 -0.44 -5.04 -0.41 1.64e-6 Diastolic blood pressure;Blood pressure traits (multi-trait analysis);Systolic blood pressure;Hypertension; TGCT cis rs1153858 0.723 rs4580098 chr15:45596909 T/A cg14582100 chr15:45693742 SPATA5L1 0.47 5.08 0.42 1.34e-6 Homoarginine levels; TGCT cis rs4689592 0.587 rs6825954 chr4:7074226 T/C cg26116260 chr4:7069785 GRPEL1 1.08 9.87 0.66 2.64e-17 Monocyte percentage of white cells; TGCT cis rs4252435 0.614 rs4252522 chr7:142603944 G/A cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs7267979 0.740 rs2259961 chr20:25282626 T/G cg16686733 chr20:25566563 NINL 0.52 4.93 0.4 2.61e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs1843834 0.505 rs7585047 chr2:225373897 C/T cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs2456568 0.741 rs9633811 chr11:93628327 A/G cg16099599 chr11:93583650 C11orf90 0.41 5.27 0.43 5.95e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7091068 0.522 rs10882323 chr10:95483280 T/C cg20715218 chr10:95462985 C10orf4 0.5 4.86 0.4 3.49e-6 Urinary tract infection frequency; TGCT cis rs7412746 0.658 rs2864869 chr1:150734655 G/A cg04414720 chr1:150670196 GOLPH3L 0.37 4.63 0.38 9.12e-6 Melanoma; TGCT cis rs10507380 0.824 rs118067250 chr13:27921825 C/T cg25543773 chr13:27185723 WASF3 0.33 4.7 0.39 6.81e-6 Electrocardiographic traits; TGCT cis rs4372836 0.677 rs4632298 chr2:29076282 T/C cg09522027 chr2:28974177 PPP1CB 0.67 6.94 0.53 1.89e-10 Body mass index; TGCT cis rs892961 0.777 rs747483 chr17:75412091 C/T cg05865280 chr17:75406074 SEPT9 0.28 6.86 0.52 2.9e-10 Airflow obstruction; TGCT cis rs950169 0.724 rs11632668 chr15:84948687 T/C cg12863693 chr15:85201151 NMB 0.45 4.96 0.41 2.28e-6 Schizophrenia; TGCT cis rs7786808 0.530 rs6459875 chr7:158186141 C/T cg01191920 chr7:158217561 PTPRN2 0.36 5.06 0.41 1.47e-6 Obesity-related traits; TGCT cis rs9372498 0.505 rs62424204 chr6:118861642 G/A cg21191810 chr6:118973309 C6orf204 -0.37 -4.79 -0.39 4.73e-6 Diastolic blood pressure; TGCT cis rs7617480 0.610 rs4955420 chr3:49208865 A/G cg06212747 chr3:49208901 KLHDC8B 0.71 6.78 0.52 4.31e-10 Subjective well-being (multi-trait analysis);Menarche (age at onset); TGCT cis rs7824557 0.564 rs2736293 chr8:11234613 T/A cg21775007 chr8:11205619 TDH -0.65 -6.4 -0.5 2.97e-9 Retinal vascular caliber; TGCT cis rs7647973 0.626 rs62260720 chr3:49853796 T/A cg05785598 chr3:49045655 WDR6 -0.43 -5.28 -0.43 5.5e-7 Menarche (age at onset); TGCT cis rs9926296 0.744 rs6860 chr16:89711120 C/T cg27121462 chr16:89883253 FANCA -0.53 -4.82 -0.4 4.19e-6 Vitiligo; TGCT cis rs858239 0.539 rs1358442 chr7:23189739 C/T cg05602783 chr7:23145260 KLHL7 -0.62 -5.03 -0.41 1.67e-6 Cerebrospinal fluid biomarker levels; TGCT cis rs752590 0.774 rs6755077 chr2:113953508 G/A cg27425262 chr2:113953981 PSD4;LOC440839 0.41 4.7 0.39 6.89e-6 Mucinous ovarian carcinoma; TGCT cis rs2153535 0.601 rs9502719 chr6:8541032 A/G cg23788917 chr6:8435910 SLC35B3 0.63 5.61 0.45 1.23e-7 Motion sickness; TGCT cis rs10751667 0.643 rs10902244 chr11:949981 A/G cg06064525 chr11:970664 AP2A2 -0.35 -8.06 -0.59 5.6e-13 Alzheimer's disease (late onset); TGCT cis rs7809950 1.000 rs17154077 chr7:107077941 C/T cg23024343 chr7:107201750 COG5 0.33 5.32 0.43 4.72e-7 Coronary artery disease; TGCT cis rs514406 0.505 rs440871 chr1:53173052 C/T cg24675658 chr1:53192096 ZYG11B -0.78 -9.2 -0.64 1.09e-15 Monocyte count; TGCT cis rs514406 0.644 rs7530078 chr1:53204861 G/T cg24675658 chr1:53192096 ZYG11B 0.86 11.3 0.71 8.54e-21 Monocyte count; TGCT cis rs3796352 0.667 rs34288509 chr3:52849493 G/C cg15956490 chr3:53032818 SFMBT1 0.54 4.8 0.4 4.55e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs7829975 0.606 rs11776838 chr8:8794801 C/T cg06636001 chr8:8085503 FLJ10661 -0.68 -6.03 -0.48 1.71e-8 Mood instability; TGCT cis rs3741404 1.000 rs11603042 chr11:64003843 G/T cg19570321 chr11:63258214 HRASLS5 0.44 4.98 0.41 2.09e-6 Platelet count; TGCT cis rs968567 1.000 rs968567 chr11:61595564 C/T cg19610905 chr11:61596333 FADS2 -0.79 -5.45 -0.44 2.66e-7 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs2486012 1.000 rs2486012 chr1:44373409 A/G cg12908607 chr1:44402522 ARTN 0.71 5.86 0.47 3.87e-8 Intelligence (multi-trait analysis); TGCT cis rs644799 0.648 rs1255176 chr11:95471465 A/T cg25622487 chr11:95524042 FAM76B;CEP57 0.51 5.05 0.41 1.55e-6 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9388451 1.000 rs9388451 chr6:126090377 A/G cg05901451 chr6:126070800 HEY2 -1.03 -14.34 -0.79 4.15e-28 Brugada syndrome; TGCT cis rs8180040 1.000 rs807931 chr3:47389317 C/T cg27129171 chr3:47204927 SETD2 0.72 8.94 0.63 4.57e-15 Colorectal cancer; TGCT cis rs9303401 0.592 rs66583824 chr17:56639853 C/T cg02118635 chr17:56770003 RAD51C;TEX14 0.62 6.32 0.49 4.18e-9 Cognitive test performance; TGCT cis rs7904368 0.754 rs66491181 chr10:16849430 T/C cg14835575 chr10:16859367 RSU1 0.67 7.37 0.55 2.16e-11 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs514406 0.560 rs1889033 chr1:53211887 A/G cg25767906 chr1:53392781 SCP2 0.46 5.11 0.42 1.17e-6 Monocyte count; TGCT cis rs9660180 0.967 rs12034740 chr1:1728969 C/A cg23982607 chr1:1823379 GNB1 -0.54 -8.16 -0.59 3.12e-13 Body mass index; TGCT cis rs2072499 0.750 rs10159384 chr1:156160822 C/T cg25208724 chr1:156163844 SLC25A44 1.01 9.25 0.64 8.38e-16 Testicular germ cell tumor; TGCT cis rs933688 1.000 rs7715402 chr5:90679504 T/A cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.03 9.55 0.65 1.54e-16 Smoking behavior; TGCT cis rs13242816 0.892 rs34645128 chr7:116078382 T/A cg16553024 chr7:116138462 CAV2 -0.47 -5.25 -0.43 6.52e-7 P wave duration; TGCT cis rs16958440 0.867 rs75481537 chr18:44719946 C/T cg17192377 chr18:44677553 HDHD2 0.63 4.7 0.39 6.74e-6 Sitting height ratio; TGCT cis rs79149102 0.579 rs7166105 chr15:75343942 A/G cg09165964 chr15:75287851 SCAMP5 1.09 6.08 0.48 1.35e-8 Lung cancer; TGCT cis rs10754283 0.934 rs10493829 chr1:90117833 T/C cg03145924 chr1:90228473 NA -0.41 -4.68 -0.39 7.24e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs3617 0.573 rs6795646 chr3:52922621 C/T cg11645453 chr3:52864694 ITIH4 -0.29 -5.52 -0.44 1.85e-7 Red blood cell count;Autism spectrum disorder or schizophrenia; TGCT cis rs1461503 0.966 rs10790546 chr11:122838426 C/A cg27398637 chr11:122830231 C11orf63 -0.43 -5.31 -0.43 5e-7 Menarche (age at onset); TGCT cis rs514406 0.505 rs440871 chr1:53173052 C/T cg25767906 chr1:53392781 SCP2 -0.45 -5.01 -0.41 1.87e-6 Monocyte count; TGCT cis rs59043219 1 rs59043219 chr1:209970610 G/A cg23283495 chr1:209979779 IRF6 0.71 8.45 0.6 6.81e-14 Crohn's disease;Inflammatory bowel disease;Alzheimer's disease (APOE e4 interaction); TGCT cis rs9443645 0.901 rs1354831 chr6:79613576 T/C cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs4819052 0.851 rs2838828 chr21:46663423 A/G cg19498844 chr21:46707878 POFUT2;LOC642852 0.75 6.75 0.52 5.18e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs9467711 0.516 rs1177441 chr6:25859413 A/G cg03517284 chr6:25882590 NA -0.73 -4.85 -0.4 3.62e-6 Autism spectrum disorder or schizophrenia; TGCT cis rs67311347 0.635 rs73071706 chr3:40288190 C/A cg13683864 chr3:40499215 RPL14 -0.84 -7.91 -0.58 1.2e-12 Renal cell carcinoma; TGCT cis rs28595532 0.920 rs114243409 chr4:119756585 C/A cg14228332 chr4:119757509 SEC24D 1.29 6.0 0.47 1.98e-8 Cannabis dependence symptom count; TGCT cis rs832540 0.801 rs7731700 chr5:56111927 C/T cg24531977 chr5:56204891 C5orf35 -0.54 -5.34 -0.43 4.33e-7 Coronary artery disease; TGCT cis rs2013441 0.932 rs2526488 chr17:20098617 T/A cg18979559 chr17:20280153 CCDC144C -0.43 -4.49 -0.37 1.61e-5 Obesity-related traits; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg25703541 chr22:24373054 LOC391322 -0.81 -8.47 -0.61 6.1e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs1008375 1.000 rs4698634 chr4:17630192 A/C cg18681998 chr4:17616180 MED28 -1.02 -11.4 -0.72 4.89e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs11190604 0.697 rs4559619 chr10:102199884 C/T cg23241863 chr10:102295624 HIF1AN -0.65 -4.9 -0.4 2.9e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs826838 0.935 rs1160162 chr12:38959795 G/A cg26384229 chr12:38710491 ALG10B 1.03 10.33 0.68 1.97e-18 Heart rate; TGCT cis rs12478296 1.000 rs12474070 chr2:243039738 C/T cg06360820 chr2:242988706 NA -0.61 -4.75 -0.39 5.52e-6 Obesity-related traits; TGCT cis rs10411936 1.000 rs16995422 chr19:16519045 A/G cg19006008 chr19:16999768 F2RL3 -0.27 -4.73 -0.39 5.95e-6 White blood cell count;Multiple sclerosis; TGCT cis rs4862750 0.957 rs4861733 chr4:187903933 C/T cg10295955 chr4:187884368 NA -0.95 -14.86 -0.8 2.58e-29 Lobe attachment (rater-scored or self-reported); TGCT cis rs4282054 0.631 rs13081155 chr3:52732429 A/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.6 -6.02 -0.48 1.83e-8 Cognitive function; TGCT cis rs12580194 0.593 rs61957936 chr12:55745719 A/G cg10672482 chr12:55725839 OR6C3 -0.52 -4.66 -0.39 8.13e-6 Cancer; TGCT cis rs6912958 0.712 rs4587138 chr6:88356915 G/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs1552244 1.000 rs55882090 chr3:10139082 C/T cg18598329 chr3:10140678 FANCD2;C3orf24 -0.48 -6.74 -0.52 5.26e-10 Alzheimer's disease; TGCT trans rs9388451 0.587 rs1739385 chr6:126099939 G/A cg05039488 chr6:79577232 IRAK1BP1 -0.8 -9.31 -0.64 5.94e-16 Brugada syndrome; TGCT cis rs9311474 0.508 rs11720159 chr3:52617802 T/G cg10802521 chr3:52805072 NEK4 -0.78 -10.01 -0.67 1.23e-17 Electroencephalogram traits; TGCT cis rs2549003 0.966 rs2070730 chr5:131819800 G/A cg02551604 chr5:131831745 NA -0.89 -11.95 -0.73 2.33e-22 Asthma (sex interaction); TGCT cis rs2692947 0.770 rs58730124 chr2:96413338 T/C cg23100626 chr2:96804247 ASTL 0.37 4.49 0.37 1.62e-5 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs7572733 0.534 rs10931794 chr2:198776140 C/T cg00792783 chr2:198669748 PLCL1 -0.56 -5.11 -0.42 1.21e-6 Dermatomyositis; TGCT cis rs2469997 1.000 rs2447176 chr8:120356892 G/A cg02248809 chr8:120845432 TAF2 0.58 4.47 0.37 1.76e-5 Hypertension (SNP x SNP interaction); TGCT cis rs4888262 0.545 rs8050624 chr16:74686690 A/G cg01733217 chr16:74700730 RFWD3 -0.74 -7.35 -0.55 2.3e-11 Testicular germ cell tumor; TGCT cis rs912057 0.797 rs1294430 chr6:6744698 A/G cg06612196 chr6:6737390 NA 0.37 4.69 0.39 7.03e-6 Waist-to-hip ratio adjusted for BMI in active individuals;Waist-to-hip ratio adjusted for body mass index;Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction); TGCT cis rs7267979 0.966 rs2261747 chr20:25261784 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9916302 0.861 rs8081033 chr17:37506650 A/G cg15445000 chr17:37608096 MED1 -0.33 -4.71 -0.39 6.46e-6 Glomerular filtration rate (creatinine); TGCT cis rs6500602 0.701 rs11643057 chr16:4544505 C/T cg14951292 chr16:4525986 HMOX2;NMRAL1 0.4 7.08 0.54 9.28e-11 Schizophrenia; TGCT cis rs11696501 0.688 rs6073861 chr20:44325708 G/A cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs7760949 0.889 rs9475807 chr6:13934597 T/C cg27413430 chr6:13925136 RNF182 0.73 6.79 0.52 4.22e-10 Mean corpuscular hemoglobin concentration; TGCT cis rs7208859 0.673 rs450585 chr17:28951039 G/A cg04154034 chr17:28927549 LRRC37B2 0.76 4.75 0.39 5.61e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs17102423 0.963 rs35002541 chr14:65598704 G/A cg11161011 chr14:65562177 MAX -0.52 -6.9 -0.53 2.37e-10 Obesity-related traits; TGCT cis rs8056742 0.730 rs35835594 chr16:85070415 T/C cg00229868 chr16:85520891 NA 0.42 5.17 0.42 9.14e-7 Amyotrophic lateral sclerosis; TGCT cis rs79349575 0.783 rs4255820 chr17:46996583 T/A cg26022315 chr17:47021804 SNF8 0.49 4.89 0.4 3.03e-6 Type 2 diabetes; TGCT cis rs10504229 0.728 rs77197419 chr8:58150879 C/A cg24829409 chr8:58192753 C8orf71 -0.59 -4.97 -0.41 2.17e-6 Developmental language disorder (linguistic errors); TGCT cis rs4665809 1.000 rs12475854 chr2:26267375 G/A cg22920501 chr2:26401640 FAM59B -0.71 -6.1 -0.48 1.27e-8 Gut microbiome composition (summer); TGCT trans rs12599106 0.560 rs34151874 chr16:34989694 G/A cg11235426 chr6:292522 DUSP22 -0.68 -6.94 -0.53 1.92e-10 Menopause (age at onset); TGCT cis rs7824557 0.564 rs2736295 chr8:11234780 C/G cg21775007 chr8:11205619 TDH 0.63 6.24 0.49 6.18e-9 Retinal vascular caliber; TGCT cis rs7267979 0.727 rs2474765 chr20:25245950 G/T cg16686733 chr20:25566563 NINL 0.51 5.1 0.42 1.22e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2739330 0.828 rs4822451 chr22:24248166 T/G cg00024416 chr22:24240387 NA -0.25 -4.76 -0.39 5.27e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12579753 0.872 rs12319937 chr12:82182545 T/G cg07988820 chr12:82153109 PPFIA2 -0.59 -6.19 -0.49 7.93e-9 Resting heart rate; TGCT cis rs854765 0.583 rs12452219 chr17:17829423 C/T cg09796270 chr17:17721594 SREBF1 0.27 5.53 0.44 1.84e-7 Total body bone mineral density; TGCT cis rs67180937 0.583 rs3008614 chr1:222796136 C/T cg09820183 chr1:222886073 C1orf58;AIDA 0.71 4.58 0.38 1.12e-5 Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease);Coronary artery disease; TGCT cis rs727563 0.552 rs4822045 chr22:41985958 C/A cg06481639 chr22:41940642 POLR3H -0.75 -6.47 -0.5 2.1e-9 Crohn's disease;Inflammatory bowel disease; TGCT cis rs9914988 0.832 rs9903248 chr17:27127439 G/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.09 -0.42 1.29e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT trans rs7618501 0.633 rs3774733 chr3:50037123 C/G cg21659725 chr3:3221576 CRBN 0.76 9.03 0.63 2.74e-15 Intelligence (multi-trait analysis); TGCT cis rs7617773 0.817 rs936427 chr3:48301074 A/G cg11946769 chr3:48343235 NME6 -0.76 -6.63 -0.51 9.31e-10 Coronary artery disease; TGCT cis rs7666738 0.606 rs13108868 chr4:99083753 C/T cg05340658 chr4:99064831 C4orf37 0.44 4.8 0.4 4.5e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs9921338 0.961 rs7206017 chr16:11440861 C/T cg00044050 chr16:11439710 C16orf75 -0.87 -6.68 -0.51 7.37e-10 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs6831352 0.918 rs29001194 chr4:100054844 A/G cg12011299 chr4:100065546 ADH4 -0.4 -4.88 -0.4 3.26e-6 Alcohol dependence; TGCT cis rs3749237 0.964 rs11714957 chr3:49776178 C/T cg03060546 chr3:49711283 APEH 0.72 7.38 0.55 2.02e-11 Resting heart rate; TGCT cis rs858239 0.632 rs7811903 chr7:23119056 A/G cg05602783 chr7:23145260 KLHL7 -0.63 -5.31 -0.43 4.93e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs2996428 0.667 rs11578581 chr1:3770642 G/A cg17848003 chr1:3704513 LRRC47 0.18 5.15 0.42 9.99e-7 Red cell distribution width; TGCT cis rs9948 0.655 rs62152785 chr2:97459403 A/T cg01990225 chr2:97406019 LMAN2L -0.88 -4.81 -0.4 4.37e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs600231 0.665 rs1784859 chr11:65220749 A/G cg21890820 chr11:65308645 LTBP3 -0.39 -4.67 -0.39 7.73e-6 Bone mineral density; TGCT cis rs617219 0.737 rs6453431 chr5:78493873 G/C cg09550809 chr5:78407562 BHMT 0.39 5.49 0.44 2.19e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs4927850 0.918 rs4361313 chr3:195752260 A/G cg02975922 chr3:195473998 MUC4 -0.24 -5.47 -0.44 2.4e-7 Pancreatic cancer; TGCT cis rs7568458 0.636 rs11126995 chr2:85792408 A/T cg17127132 chr2:85788382 GGCX 0.55 5.0 0.41 1.88e-6 Coronary artery disease;Coronary artery disease (myocardial infartum, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease); TGCT cis rs4663866 0.901 rs3739066 chr2:239184124 G/T cg17283117 chr2:239148619 HES6 0.99 4.58 0.38 1.12e-5 Irritable bowel syndrome; TGCT cis rs10504229 1.000 rs112284078 chr8:58191640 A/G cg08219700 chr8:58056026 NA 0.3 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs875971 0.660 rs1860468 chr7:66107252 T/C cg00343986 chr7:65444356 GUSB -0.24 -5.29 -0.43 5.43e-7 Aortic root size; TGCT cis rs789852 0.717 rs789997 chr3:194328524 A/G cg18000598 chr3:194342907 TMEM44 -0.9 -5.51 -0.44 2e-7 QT interval; TGCT cis rs3782455 0.590 rs16943539 chr12:114404337 T/G cg10631684 chr12:113795897 PLBD2 -0.7 -4.61 -0.38 1e-5 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs1215050 0.755 rs1238462 chr4:98850603 A/G cg17366294 chr4:99064904 C4orf37 -0.57 -6.12 -0.48 1.13e-8 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6952808 0.931 rs12537430 chr7:1868761 A/G cg22963979 chr7:1858916 MAD1L1 0.3 4.65 0.39 8.24e-6 Bipolar disorder and schizophrenia; TGCT cis rs2229238 0.911 rs60760897 chr1:154504849 C/T cg13067139 chr1:155221277 FAM189B 0.2 4.51 0.38 1.47e-5 Coronary heart disease; TGCT cis rs10986311 0.722 rs6478660 chr9:127133920 A/T cg14243010 chr9:127117328 LOC100129034;PSMB7 0.19 4.88 0.4 3.23e-6 Vitiligo; TGCT cis rs2019137 0.560 rs6707386 chr2:113981022 G/A cg23156509 chr2:114033830 PAX8;LOC440839 -0.32 -4.9 -0.4 2.91e-6 Lymphocyte counts; TGCT cis rs79976124 0.879 rs17432710 chr6:66621744 T/C cg07460842 chr6:66804631 NA 0.58 5.17 0.42 8.91e-7 Type 2 diabetes; TGCT cis rs12497850 0.931 rs9846123 chr3:49088112 C/T cg18654377 chr3:49208889 KLHDC8B 0.41 5.4 0.44 3.33e-7 Parkinson's disease; TGCT cis rs1113500 0.787 rs473704 chr1:108637310 T/C cg22161131 chr1:109420278 GPSM2 -0.49 -4.54 -0.38 1.34e-5 Growth-regulated protein alpha levels; TGCT cis rs2762353 0.639 rs566530 chr6:25878361 T/C cg12310025 chr6:25882481 NA -0.65 -7.17 -0.54 5.94e-11 Blood metabolite levels; TGCT cis rs11174478 0.966 rs4768204 chr12:40351086 A/T cg12664938 chr12:40622688 LRRK2 0.23 4.59 0.38 1.05e-5 Insomnia; TGCT cis rs2657888 0.628 rs7314242 chr12:56876372 C/A cg23002907 chr12:56915593 RBMS2 -0.41 -5.37 -0.43 3.76e-7 Adiponectin levels; TGCT cis rs35306767 0.953 rs11253509 chr10:964306 C/T cg18964960 chr10:1102726 WDR37 0.57 4.55 0.38 1.27e-5 Eosinophil percentage of granulocytes; TGCT cis rs7666738 0.535 rs6850010 chr4:98971601 A/T cg18180107 chr4:99064573 C4orf37 0.5 4.46 0.37 1.84e-5 Colonoscopy-negative controls vs population controls; TGCT cis rs7811142 0.830 rs28495773 chr7:99943583 A/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.0 7.47 0.56 1.24e-11 Platelet count; TGCT cis rs8177253 0.530 rs8177177 chr3:133463195 A/G cg24879335 chr3:133465180 TF 0.37 4.89 0.4 3.03e-6 Iron status biomarkers; TGCT trans rs57221529 0.766 rs4081846 chr5:574019 G/A cg25482853 chr8:67687455 SGK3 1.19 10.96 0.7 5.68e-20 Lung disease severity in cystic fibrosis; TGCT cis rs1348850 0.567 rs3770005 chr2:178528874 A/G cg22681709 chr2:178499509 PDE11A -0.48 -5.94 -0.47 2.7e-8 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs8072100 0.967 rs2317826 chr17:45730899 C/T cg08085267 chr17:45401833 C17orf57 -0.47 -5.12 -0.42 1.14e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs4820539 0.902 rs737846 chr22:23460669 A/G cg21100191 chr22:23484243 RTDR1 0.94 11.48 0.72 3.14e-21 Bone mineral density; TGCT cis rs6977660 0.714 rs17141884 chr7:19790280 A/G cg07541023 chr7:19748670 TWISTNB -0.84 -5.05 -0.41 1.55e-6 Thyroid stimulating hormone; TGCT cis rs2692947 0.655 rs2315668 chr2:96429562 T/C cg23100626 chr2:96804247 ASTL 0.4 4.78 0.39 4.84e-6 Eosinophil percentage of granulocytes;Neutrophil percentage of granulocytes; TGCT cis rs473651 0.935 rs472357 chr2:239355454 A/G cg08773314 chr2:239334832 ASB1 -0.44 -7.21 -0.54 4.93e-11 Multiple system atrophy; TGCT cis rs9393692 0.905 rs6940237 chr6:26282322 T/C cg13736514 chr6:26305472 NA -0.41 -5.77 -0.46 6.09e-8 Educational attainment; TGCT cis rs3820068 0.655 rs72645826 chr1:15889741 A/G cg05660106 chr1:15850417 CASP9 1.17 14.8 0.8 3.47e-29 Systolic blood pressure; TGCT cis rs950776 0.684 rs11637635 chr15:78877150 A/G cg06917634 chr15:78832804 PSMA4 -0.66 -5.29 -0.43 5.47e-7 Sudden cardiac arrest; TGCT cis rs9807989 0.801 rs10176664 chr2:102976172 G/A cg09003973 chr2:102972529 NA 0.67 6.03 0.48 1.75e-8 Asthma; TGCT cis rs2239547 0.563 rs4687699 chr3:53101224 C/T cg11645453 chr3:52864694 ITIH4 0.34 5.59 0.45 1.38e-7 Schizophrenia; TGCT cis rs6840360 0.809 rs6847303 chr4:152730221 G/A cg22705602 chr4:152727874 NA 0.27 4.82 0.4 4.09e-6 Intelligence (multi-trait analysis); TGCT cis rs7563124 1 rs7563124 chr2:113965198 T/A cg27425262 chr2:113953981 PSD4;LOC440839 0.4 4.67 0.39 7.79e-6 Hematocrit; TGCT cis rs7312933 0.558 rs1796394 chr12:42826359 G/A cg19980929 chr12:42632907 YAF2 -0.4 -5.7 -0.46 8.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs9467773 1.000 rs6910899 chr6:26524339 A/G cg09904177 chr6:26538194 HMGN4 0.65 6.53 0.51 1.53e-9 Intelligence (multi-trait analysis); TGCT cis rs11190604 0.767 rs10883491 chr10:102196071 G/T cg23241863 chr10:102295624 HIF1AN 0.64 4.8 0.4 4.42e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs28595532 0.920 rs115334469 chr4:119596194 G/C cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.66e-7 Cannabis dependence symptom count; TGCT cis rs5769707 0.681 rs916360 chr22:50041972 T/C cg05373962 chr22:49881684 NA -0.34 -5.66 -0.45 1.01e-7 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1670533 0.872 rs11727135 chr4:1051803 G/C cg20887711 chr4:1340912 KIAA1530 0.63 5.03 0.41 1.65e-6 Recombination rate (females); TGCT cis rs12681287 0.640 rs6992944 chr8:87419308 G/T cg27223183 chr8:87520930 FAM82B 0.89 6.36 0.5 3.45e-9 Caudate activity during reward; TGCT cis rs9486719 0.843 rs3860231 chr6:97036563 G/A cg06623918 chr6:96969491 KIAA0776 -1.04 -10.25 -0.68 3.11e-18 Migraine;Coronary artery disease; TGCT cis rs9534288 0.783 rs7987385 chr13:46634131 A/G cg15192986 chr13:46630673 CPB2 -0.5 -6.23 -0.49 6.66e-9 Blood protein levels; TGCT cis rs12421382 0.636 rs60266280 chr11:109387766 A/C cg16359550 chr11:109292809 C11orf87 0.42 4.68 0.39 7.36e-6 Schizophrenia; TGCT cis rs3764400 0.567 rs3897789 chr17:46312777 C/T cg02340556 chr17:46797764 NA 0.42 4.51 0.38 1.46e-5 Body mass index; TGCT cis rs3849570 1.000 rs3772883 chr3:81802802 C/T cg07356753 chr3:81810745 GBE1 -0.71 -6.13 -0.48 1.08e-8 Waist circumference;Body mass index; TGCT cis rs2204008 0.774 rs2387811 chr12:38369794 C/A cg26384229 chr12:38710491 ALG10B 0.84 7.3 0.55 2.97e-11 Bladder cancer; TGCT cis rs9381040 0.655 rs9394756 chr6:41016183 A/G cg03526776 chr6:41159608 TREML2 0.26 5.06 0.41 1.44e-6 Alzheimer's disease (late onset); TGCT cis rs778371 0.676 rs921055 chr2:233697337 A/C cg08000102 chr2:233561755 GIGYF2 -0.67 -7.64 -0.57 5.21e-12 Schizophrenia; TGCT cis rs7178572 0.743 rs62009090 chr15:77837055 T/G cg22256960 chr15:77711686 NA -0.86 -9.93 -0.67 1.88e-17 Type 2 diabetes; TGCT cis rs155076 0.938 rs261375 chr13:21871882 A/G cg11317459 chr13:21872234 NA 1.4 11.14 0.71 2.1e-20 White matter hyperintensity burden; TGCT cis rs9733 0.596 rs11204697 chr1:150658971 C/T cg09365446 chr1:150670422 GOLPH3L 0.31 4.64 0.38 8.7e-6 Tonsillectomy; TGCT cis rs9796 0.689 rs692195 chr15:41444894 G/C cg18705301 chr15:41695430 NDUFAF1 -0.53 -6.84 -0.52 3.16e-10 Menopause (age at onset); TGCT cis rs453301 0.571 rs2929454 chr8:9083854 A/C cg06636001 chr8:8085503 FLJ10661 -0.56 -4.97 -0.41 2.14e-6 Joint mobility (Beighton score); TGCT cis rs9614461 0.702 rs3788648 chr22:45727180 G/A cg01808030 chr22:45809952 RIBC2;SMC1B 0.75 4.45 0.37 1.91e-5 Tonsillectomy; TGCT cis rs9372498 0.536 rs9320656 chr6:118894468 A/G cg21191810 chr6:118973309 C6orf204 0.39 5.04 0.41 1.59e-6 Diastolic blood pressure; TGCT cis rs1059312 0.932 rs4760592 chr12:129287149 G/C cg09035930 chr12:129282057 SLC15A4 0.58 11.18 0.71 1.67e-20 Systemic lupus erythematosus; TGCT cis rs3733585 0.699 rs4339211 chr4:9947658 C/T cg00071950 chr4:10020882 SLC2A9 -0.56 -6.45 -0.5 2.22e-9 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs6893807 0.667 rs2304607 chr5:87988733 A/G cg24804195 chr5:87968844 LOC645323 0.66 4.68 0.39 7.26e-6 Body mass index; TGCT cis rs477895 0.838 rs11605738 chr11:64013406 G/A cg23719950 chr11:63933701 MACROD1 -0.69 -5.74 -0.46 6.94e-8 Mean platelet volume; TGCT cis rs7666738 0.747 rs2865955 chr4:99040518 A/C cg05340658 chr4:99064831 C4orf37 0.52 5.82 0.46 4.7e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs6582630 0.622 rs11182004 chr12:38441254 G/A cg26384229 chr12:38710491 ALG10B -0.54 -4.81 -0.4 4.32e-6 Drug-induced liver injury (flucloxacillin); TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg02953382 chr22:24373134 LOC391322 0.81 6.9 0.53 2.34e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs62380364 0.557 rs663046 chr5:88036486 C/T cg24804195 chr5:87968844 LOC645323 -0.61 -6.27 -0.49 5.52e-9 Intelligence (multi-trait analysis); TGCT cis rs9549367 0.577 rs3024718 chr13:113813853 C/T cg18105134 chr13:113819100 PROZ 0.45 7.26 0.55 3.75e-11 Platelet distribution width; TGCT cis rs1153858 1.000 rs7494956 chr15:45668565 T/C cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs9611565 0.649 rs139540 chr22:42178040 C/T cg06634786 chr22:41940651 POLR3H -0.81 -7.44 -0.56 1.45e-11 Vitiligo; TGCT cis rs2074038 1.000 rs2074038 chr11:44087989 G/T cg00452199 chr11:44088257 ACCS -0.78 -7.67 -0.57 4.42e-12 IgA nephropathy; TGCT cis rs4285028 0.948 rs10934565 chr3:121664661 G/A cg01951420 chr3:121553821 IQCB1;EAF2 -0.77 -6.5 -0.5 1.78e-9 Multiple sclerosis; TGCT cis rs11690462 0.963 rs6748996 chr2:26590084 T/G cg11525280 chr2:26624667 C2orf39 0.37 4.52 0.38 1.4e-5 Coronary artery disease; TGCT cis rs7666738 0.830 rs17027216 chr4:99009152 G/C cg05340658 chr4:99064831 C4orf37 0.48 5.49 0.44 2.15e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs889312 0.500 rs866223 chr5:56125353 A/G cg12311346 chr5:56204834 C5orf35 -0.46 -5.01 -0.41 1.85e-6 Breast cancer;Breast cancer (early onset); TGCT cis rs492146 0.819 rs5028437 chr6:52835674 T/C cg06706454 chr6:52930286 FBXO9 0.5 4.63 0.38 9.12e-6 Epilepsy (remission after treatment); TGCT cis rs6484504 0.600 rs12796587 chr11:31266443 T/C cg14844989 chr11:31128820 NA -0.25 -4.84 -0.4 3.76e-6 Red blood cell count; TGCT cis rs9611519 0.929 rs73174660 chr22:41437304 T/C cg03806693 chr22:41940476 POLR3H -0.68 -6.1 -0.48 1.25e-8 Neuroticism; TGCT cis rs3091242 0.933 rs11249251 chr1:25770188 C/G cg09222892 chr1:25734099 RHCE -0.42 -7.15 -0.54 6.72e-11 Erythrocyte sedimentation rate; TGCT cis rs854765 0.654 rs11078400 chr17:17757728 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.74 -7.65 -0.57 4.87e-12 Total body bone mineral density; TGCT cis rs9322193 0.923 rs9371486 chr6:150153226 T/C cg13206674 chr6:150067644 NUP43 0.54 4.61 0.38 1e-5 Lung cancer; TGCT cis rs2594989 0.836 rs347607 chr3:11268021 A/C cg00170343 chr3:11313890 ATG7 -0.77 -4.73 -0.39 6.04e-6 Circulating chemerin levels; TGCT cis rs4819052 0.851 rs2877019 chr21:46658647 G/A cg06618935 chr21:46677482 NA -0.37 -5.81 -0.46 5.06e-8 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs61990749 0.500 rs8011337 chr14:78272626 T/G cg23188588 chr14:78226832 SNW1;C14orf178 0.67 4.73 0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT cis rs950169 0.800 rs34302901 chr15:85110943 C/G cg11189052 chr15:85197271 WDR73 0.77 6.42 0.5 2.68e-9 Schizophrenia; TGCT cis rs8014252 0.803 rs8006487 chr14:71011934 G/A cg11204974 chr14:71022665 NA -0.53 -4.46 -0.37 1.79e-5 Plasma estrone levels in resected estrogen-receptor positive breast cancer; TGCT cis rs4268898 0.722 rs6723257 chr2:24391129 A/G cg05570707 chr2:24270316 C2orf44 0.48 4.59 0.38 1.08e-5 Asthma; TGCT cis rs6724607 1.000 rs11680758 chr2:191446268 T/G cg21644426 chr2:191273491 MFSD6 0.62 6.15 0.48 9.57e-9 Pulse pressure; TGCT cis rs875971 0.929 rs34406470 chr7:65929956 A/G cg18876405 chr7:65276391 NA 0.31 4.79 0.4 4.58e-6 Aortic root size; TGCT cis rs793571 0.502 rs411007 chr15:59078502 G/C cg05156742 chr15:59063176 FAM63B 0.57 5.36 0.43 3.92e-7 Schizophrenia; TGCT cis rs6693567 0.565 rs698921 chr1:150379517 G/A cg09579323 chr1:150459698 TARS2 0.52 4.64 0.38 8.63e-6 Migraine; TGCT cis rs2130392 0.892 rs11728389 chr4:185622046 C/T cg14471096 chr4:185570637 CCDC111;CASP3 -0.56 -5.06 -0.41 1.49e-6 Kawasaki disease; TGCT cis rs4654899 0.865 rs12131353 chr1:21321163 C/G cg01072550 chr1:21505969 NA -0.46 -6.94 -0.53 1.96e-10 Superior frontal gyrus grey matter volume; TGCT cis rs13217239 0.608 rs6930508 chr6:27053142 T/C cg07220782 chr6:26987966 LOC100270746;C6orf41 -0.42 -4.61 -0.38 1.01e-5 Schizophrenia; TGCT cis rs9457247 0.967 rs1187532 chr6:167382020 G/A cg23791538 chr6:167370224 RNASET2 -0.5 -4.98 -0.41 2.08e-6 Crohn's disease; TGCT cis rs6500602 0.702 rs11645519 chr16:4538989 G/A cg08645402 chr16:4508243 NA 0.18 5.07 0.41 1.39e-6 Schizophrenia; TGCT cis rs10504229 0.683 rs79262965 chr8:58129826 G/T cg11062466 chr8:58055876 NA 0.42 4.49 0.37 1.61e-5 Developmental language disorder (linguistic errors); TGCT cis rs7824557 0.767 rs11775635 chr8:11164865 G/A cg21775007 chr8:11205619 TDH 0.58 5.46 0.44 2.46e-7 Retinal vascular caliber; TGCT cis rs7267979 1.000 rs6076339 chr20:25348712 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs3809566 0.534 rs55962736 chr15:63333892 G/T cg08198488 chr15:63333792 TPM1 -0.31 -4.62 -0.38 9.38e-6 Platelet count; TGCT cis rs1862618 0.853 rs252915 chr5:56121754 C/T cg03609598 chr5:56110824 MAP3K1 0.58 4.7 0.39 6.72e-6 Initial pursuit acceleration; TGCT cis rs40363 0.620 rs1137454 chr16:3533577 C/G cg00484396 chr16:3507460 NAT15 -0.4 -6.06 -0.48 1.5e-8 Tuberculosis; TGCT cis rs2075371 0.897 rs1646702 chr7:134000177 C/G cg11752832 chr7:134001865 SLC35B4 0.7 6.44 0.5 2.41e-9 Mean platelet volume; TGCT cis rs4253772 0.637 rs6008357 chr22:46652104 T/G cg09491104 chr22:46646882 C22orf40 -0.62 -6.49 -0.5 1.87e-9 LDL cholesterol;Cholesterol, total; TGCT cis rs909674 0.818 rs8136980 chr22:39844574 G/A cg24399712 chr22:39784796 NA -1.05 -11.84 -0.73 4.14e-22 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs28386778 0.897 rs2727295 chr17:61887693 C/T cg01411255 chr17:61851458 DDX42;CCDC47 0.75 7.16 0.54 6.1e-11 Prudent dietary pattern; TGCT cis rs11718455 0.960 rs13060222 chr3:44005046 A/T cg08738300 chr3:44038990 NA 0.85 6.34 0.49 3.94e-9 Coronary artery disease; TGCT cis rs2235649 0.592 rs7197113 chr16:1969483 G/A cg02432467 chr16:1963432 HS3ST6 -0.3 -4.56 -0.38 1.2e-5 Blood metabolite levels; TGCT cis rs7811142 0.943 rs73403312 chr7:100024153 T/C cg00814883 chr7:100076585 TSC22D4 -0.92 -9.76 -0.66 4.73e-17 Platelet count; TGCT cis rs7635838 0.892 rs9836167 chr3:11493392 C/T cg00170343 chr3:11313890 ATG7 0.66 6.0 0.47 2.03e-8 HDL cholesterol; TGCT cis rs17253792 0.749 rs45458197 chr14:56145018 A/T cg01858014 chr14:56050164 KTN1 -0.35 -4.62 -0.38 9.37e-6 Putamen volume; TGCT cis rs2688608 0.592 rs11000758 chr10:75493610 A/T cg23231163 chr10:75533350 FUT11 -0.28 -4.68 -0.39 7.4e-6 Inflammatory bowel disease; TGCT cis rs17001868 0.568 rs2075764 chr22:40758581 C/T cg07138101 chr22:40742427 ADSL 0.74 5.64 0.45 1.11e-7 Mammographic density (dense area); TGCT cis rs35306767 0.903 rs12762228 chr10:880854 G/A cg20503657 chr10:835505 NA 0.77 11.34 0.71 6.95e-21 Eosinophil percentage of granulocytes; TGCT cis rs3784262 1.000 rs7165247 chr15:58251786 C/T cg12031962 chr15:58353849 ALDH1A2 0.5 7.79 0.57 2.33e-12 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9467773 0.620 rs2494700 chr6:26631306 C/T cg02458000 chr6:26745757 NA 0.53 5.02 0.41 1.76e-6 Intelligence (multi-trait analysis); TGCT cis rs6088590 0.707 rs67159833 chr20:33488079 T/C cg24642439 chr20:33292090 TP53INP2 0.61 4.85 0.4 3.58e-6 Coronary artery disease; TGCT cis rs4665809 1.000 rs4665308 chr2:26330514 C/A cg04944784 chr2:26401820 FAM59B -0.67 -6.16 -0.48 9.54e-9 Gut microbiome composition (summer); TGCT cis rs6714710 0.603 rs55776387 chr2:98405034 T/C cg26665480 chr2:98280029 ACTR1B 0.66 6.27 0.49 5.45e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs514406 0.830 rs533935 chr1:53308807 T/C cg01802117 chr1:53393560 SCP2 -0.43 -4.99 -0.41 1.97e-6 Monocyte count; TGCT cis rs12510870 0.599 rs34832471 chr4:74434741 G/A cg05868023 chr4:75230803 EREG -0.52 -4.53 -0.38 1.39e-5 Iris color (b* coordinate); TGCT cis rs2404602 0.716 rs17460201 chr15:76673627 C/T cg26408565 chr15:76604113 ETFA 0.39 4.94 0.41 2.47e-6 Blood metabolite levels; TGCT cis rs6831352 0.918 rs13110176 chr4:100062430 C/T cg12011299 chr4:100065546 ADH4 0.44 5.28 0.43 5.52e-7 Alcohol dependence; TGCT cis rs2050392 0.624 rs303435 chr10:30731491 T/C cg13289132 chr10:30722225 MAP3K8 -0.46 -5.83 -0.46 4.59e-8 Inflammatory bowel disease; TGCT trans rs2727020 0.553 rs7479975 chr11:49581964 C/G cg03929089 chr4:120376271 NA -0.65 -7.47 -0.56 1.22e-11 Coronary artery disease; TGCT cis rs7731657 0.537 rs4706002 chr5:130373830 C/T cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT cis rs13108904 0.539 rs13135102 chr4:1330983 A/C cg00684032 chr4:1343700 KIAA1530 0.22 4.73 0.39 5.89e-6 Obesity-related traits; TGCT cis rs1153858 1.000 rs4775937 chr15:45678614 C/A cg14582100 chr15:45693742 SPATA5L1 0.49 5.73 0.46 7.14e-8 Homoarginine levels; TGCT cis rs6933660 0.646 rs3736176 chr6:151773320 T/A cg17179660 chr6:151773299 C6orf211;RMND1 -0.57 -5.41 -0.44 3.08e-7 Menarche (age at onset); TGCT cis rs10465746 0.682 rs882897 chr1:84426049 A/T cg10977910 chr1:84465055 TTLL7 0.69 7.07 0.54 9.97e-11 Obesity-related traits; TGCT cis rs3749237 0.595 rs4855873 chr3:49459114 A/C cg02487422 chr3:49467188 NICN1 0.58 5.92 0.47 3e-8 Resting heart rate; TGCT cis rs763014 0.898 rs1045277 chr16:633125 T/C cg07343612 chr16:622815 PIGQ -0.41 -7.87 -0.58 1.52e-12 Height; TGCT cis rs5769707 0.874 rs9616714 chr22:50050859 G/A cg05373962 chr22:49881684 NA -0.32 -6.56 -0.51 1.34e-9 Monocyte count;Monocyte percentage of white cells; TGCT cis rs1008375 0.931 rs6831211 chr4:17697009 G/A cg18681998 chr4:17616180 MED28 0.79 7.42 0.55 1.61e-11 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs739496 0.843 rs848129 chr12:111997502 G/C cg10833066 chr12:111807467 FAM109A 0.37 5.2 0.42 8.01e-7 Platelet count; TGCT cis rs7829975 0.533 rs7820146 chr8:8699757 T/A cg08975724 chr8:8085496 FLJ10661 0.55 4.86 0.4 3.5e-6 Mood instability; TGCT cis rs2963155 0.518 rs10515522 chr5:142758394 A/G cg17617527 chr5:142782415 NR3C1 0.79 4.94 0.41 2.46e-6 Breast cancer; TGCT cis rs7178572 1.000 rs965480 chr15:77781926 A/G cg22256960 chr15:77711686 NA -0.95 -10.89 -0.7 8.57e-20 Type 2 diabetes; TGCT cis rs7937682 0.889 rs487985 chr11:111517908 G/A cg09085632 chr11:111637200 PPP2R1B -1.1 -11.55 -0.72 2.11e-21 Primary sclerosing cholangitis; TGCT cis rs4925386 0.681 rs2427295 chr20:60927431 G/A cg06026331 chr20:60912101 LAMA5 0.34 5.46 0.44 2.48e-7 Colorectal cancer;Colorectal cancer (SNP x SNP interaction); TGCT cis rs514406 0.858 rs574853 chr1:53310959 A/T cg27535305 chr1:53392650 SCP2 -0.25 -4.79 -0.4 4.59e-6 Monocyte count; TGCT cis rs10504229 0.817 rs114173899 chr8:58170640 G/T cg24829409 chr8:58192753 C8orf71 -0.56 -5.28 -0.43 5.51e-7 Developmental language disorder (linguistic errors); TGCT cis rs899997 1.000 rs9888691 chr15:79010046 T/C cg00061860 chr15:78953028 NA -0.25 -4.67 -0.39 7.76e-6 Coronary artery disease or large artery stroke; TGCT cis rs7949030 0.596 rs71490394 chr11:62370155 G/A cg11742103 chr11:62369870 EML3;MTA2 0.61 8.75 0.62 1.29e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs10193935 1.000 rs13419669 chr2:42387254 T/C cg27598129 chr2:42591480 NA -0.39 -5.14 -0.42 1.05e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs13256369 1.000 rs4841016 chr8:8572561 C/T cg17143192 chr8:8559678 CLDN23 0.62 5.82 0.46 4.82e-8 Obesity-related traits; TGCT cis rs933688 0.532 rs13164949 chr5:90538489 C/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 -0.54 -4.82 -0.4 4.09e-6 Smoking behavior; TGCT cis rs7208859 0.623 rs9890862 chr17:29125450 C/A cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs11249608 0.548 rs13156530 chr5:178475017 C/T cg21905437 chr5:178450457 ZNF879 0.43 4.49 0.37 1.59e-5 Pubertal anthropometrics; TGCT cis rs72781680 0.898 rs12619525 chr2:23999565 G/C cg08917208 chr2:24149416 ATAD2B 0.81 5.01 0.41 1.8e-6 Lymphocyte counts; TGCT cis rs2180341 1.000 rs2038378 chr6:127590400 C/T cg27446573 chr6:127587934 RNF146 1.11 9.86 0.66 2.76e-17 Breast cancer; TGCT cis rs7937612 1.000 rs10892578 chr11:120308290 A/G cg24566217 chr11:120254723 ARHGEF12 -0.29 -4.86 -0.4 3.43e-6 Intraocular pressure; TGCT trans rs2688608 0.592 rs12253429 chr10:75496161 C/G cg13918328 chr10:52500089 ASAH2B 0.68 6.7 0.52 6.48e-10 Inflammatory bowel disease; TGCT cis rs6570726 0.846 rs9399559 chr6:145945778 C/T cg05347473 chr6:146136440 FBXO30 0.48 4.53 0.38 1.38e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs67311347 1.000 rs9848083 chr3:40466979 A/G cg17264618 chr3:40429014 ENTPD3 -0.32 -4.76 -0.39 5.36e-6 Renal cell carcinoma; TGCT cis rs7178572 0.568 rs12905951 chr15:77649431 G/A cg22256960 chr15:77711686 NA -0.85 -8.73 -0.62 1.4e-14 Type 2 diabetes; TGCT cis rs7017914 0.967 rs13271442 chr8:71585169 T/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.54 -5.03 -0.41 1.69e-6 Bone mineral density; TGCT cis rs6540559 0.673 rs926346 chr1:209962204 A/T cg23283495 chr1:209979779 IRF6 0.65 5.02 0.41 1.76e-6 Cleft lip with or without cleft palate; TGCT cis rs644799 0.544 rs1727165 chr11:95521648 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.55 5.67 0.45 9.5e-8 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs9467773 0.620 rs4368798 chr6:26593471 A/G cg02458000 chr6:26745757 NA 0.51 4.77 0.39 5.08e-6 Intelligence (multi-trait analysis); TGCT cis rs6490294 0.529 rs7137386 chr12:112283914 T/G cg10833066 chr12:111807467 FAM109A 0.32 4.99 0.41 2.02e-6 Mean platelet volume; TGCT cis rs873946 0.648 rs12771651 chr10:134554482 C/A cg05985448 chr10:134359359 INPP5A 0.22 4.9 0.4 2.97e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs11578119 0.902 rs2183372 chr1:170504019 G/A cg09767346 chr1:170501363 GORAB -0.62 -5.11 -0.42 1.18e-6 Male-pattern baldness; TGCT cis rs7547997 0.685 rs12734093 chr1:158358660 G/A cg03528325 chr1:158223921 CD1A 0.33 4.56 0.38 1.22e-5 QRS duration; TGCT cis rs9388451 0.874 rs13209968 chr6:126089285 G/C cg05901451 chr6:126070800 HEY2 -1.02 -15.06 -0.8 8.77e-30 Brugada syndrome; TGCT cis rs11098499 0.575 rs907204 chr4:120238654 G/A cg09307838 chr4:120376055 NA 0.61 5.84 0.46 4.35e-8 Corneal astigmatism; TGCT cis rs28386778 0.897 rs2584615 chr17:61927774 T/C cg23090583 chr17:61904693 PSMC5;FTSJ3 1.1 16.15 0.82 2.71e-32 Prudent dietary pattern; TGCT cis rs4862750 0.914 rs1346127 chr4:187876389 C/T cg22105103 chr4:187893119 NA -0.32 -4.44 -0.37 1.97e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs709400 0.627 rs55859054 chr14:103953666 T/A cg26031613 chr14:104095156 KLC1 0.83 9.11 0.63 1.75e-15 Body mass index; TGCT cis rs6912958 0.712 rs6908386 chr6:88354746 T/C cg08069147 chr6:88032118 GJB7;C6orf162 -0.49 -4.55 -0.38 1.26e-5 Monocyte percentage of white cells; TGCT cis rs6087990 0.899 rs4911107 chr20:31374991 G/A cg13636640 chr20:31349939 DNMT3B 1.1 14.78 0.8 3.97e-29 Ulcerative colitis; TGCT cis rs796364 1.000 rs71424239 chr2:200725473 T/C cg17644776 chr2:200775616 C2orf69 -0.31 -4.69 -0.39 7.18e-6 Schizophrenia; TGCT cis rs597539 0.654 rs619727 chr11:68627535 A/G cg21862992 chr11:68658383 NA 0.46 6.35 0.5 3.74e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs17376456 0.825 rs1470150 chr5:93138654 C/T cg25358565 chr5:93447407 FAM172A -0.87 -8.22 -0.59 2.28e-13 Diabetic retinopathy; TGCT cis rs10504229 1.000 rs34616626 chr8:58184650 C/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs6951245 0.744 rs10265736 chr7:1172465 C/T cg27454412 chr7:1067447 C7orf50 0.56 4.72 0.39 6.28e-6 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10479542 0.544 rs7706275 chr5:178990305 A/G cg21226059 chr5:178986404 RUFY1 0.51 5.51 0.44 2e-7 Lung cancer; TGCT cis rs2594989 0.943 rs2454492 chr3:11507793 G/A cg00170343 chr3:11313890 ATG7 0.76 5.57 0.45 1.51e-7 Circulating chemerin levels; TGCT cis rs4891159 0.584 rs689878 chr18:74152017 C/T cg24786174 chr18:74118243 ZNF516 0.66 11.85 0.73 3.89e-22 Longevity; TGCT cis rs2980439 0.818 rs2948294 chr8:8094961 A/G cg06636001 chr8:8085503 FLJ10661 0.87 8.77 0.62 1.18e-14 Neuroticism; TGCT cis rs10751667 0.666 rs7943140 chr11:973824 T/C cg06064525 chr11:970664 AP2A2 -0.34 -7.97 -0.58 9.04e-13 Alzheimer's disease (late onset); TGCT cis rs28735056 0.935 rs552957 chr18:77595748 G/A cg20368463 chr18:77673604 PQLC1 -0.49 -5.93 -0.47 2.81e-8 Schizophrenia; TGCT cis rs6912958 0.781 rs7761814 chr6:88188309 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.54 -5.23 -0.43 7.03e-7 Monocyte percentage of white cells; TGCT cis rs1395 1.000 rs1141313 chr2:27460968 A/G cg14242246 chr2:27434262 C2orf28;SLC5A6 0.51 6.77 0.52 4.66e-10 Blood metabolite levels; TGCT cis rs9303401 0.580 rs12946396 chr17:57164195 T/A cg02118635 chr17:56770003 RAD51C;TEX14 0.58 5.74 0.46 6.76e-8 Cognitive test performance; TGCT cis rs9929218 0.953 rs2902323 chr16:68736292 C/T cg01251360 chr16:68772225 CDH1 0.29 4.66 0.39 8.19e-6 Colorectal cancer; TGCT cis rs3741404 0.895 rs2429455 chr11:63995302 C/G cg03236948 chr11:63997492 DNAJC4 0.37 4.63 0.38 8.93e-6 Platelet count; TGCT cis rs10504229 0.679 rs72649115 chr8:58037631 T/G cg11062466 chr8:58055876 NA 0.46 4.91 0.4 2.8e-6 Developmental language disorder (linguistic errors); TGCT cis rs58722170 0.627 rs12039431 chr1:38082122 G/A cg17933807 chr1:38061675 GNL2 -0.86 -8.69 -0.62 1.83e-14 High-grade serous ovarian cancer;Serous invasive ovarian cancer;Epithelial ovarian cancer; TGCT cis rs7552404 0.924 rs1858536 chr1:76161595 G/T cg22875332 chr1:76189707 ACADM 0.78 9.74 0.66 5.53e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs9467773 0.550 rs9379874 chr6:26440429 A/T cg15659132 chr6:26577336 NA -0.43 -4.51 -0.38 1.47e-5 Intelligence (multi-trait analysis); TGCT cis rs1483890 0.723 rs6783070 chr3:69411596 A/C cg22125112 chr3:69402811 FRMD4B -0.3 -4.93 -0.4 2.62e-6 Resting heart rate; TGCT cis rs67311347 1.000 rs73078158 chr3:40472567 G/C cg17264618 chr3:40429014 ENTPD3 0.34 4.94 0.41 2.52e-6 Renal cell carcinoma; TGCT cis rs1453308 1.000 rs4663644 chr2:237185511 T/A cg19324714 chr2:237145437 ASB18 0.59 5.21 0.42 7.8e-7 Estrone/androstenedione ratio in resected early stage-receptor positive breast cancer; TGCT cis rs858239 0.601 rs6461693 chr7:23160133 A/G cg05602783 chr7:23145260 KLHL7 0.63 5.27 0.43 5.84e-7 Cerebrospinal fluid biomarker levels; TGCT cis rs9325144 0.600 rs12227663 chr12:38734922 C/T cg26384229 chr12:38710491 ALG10B -0.61 -5.58 -0.45 1.43e-7 Morning vs. evening chronotype; TGCT cis rs7439150 0.954 rs2227411 chr4:155489085 A/G cg22130008 chr4:155548532 NA -0.54 -6.51 -0.5 1.66e-9 Fibrinogen levels; TGCT cis rs11096990 0.576 rs2008679 chr4:39268005 A/C cg20847110 chr4:39482781 LOC401127 -0.16 -4.53 -0.38 1.36e-5 Cognitive function; TGCT cis rs2688608 0.869 rs2633308 chr10:75653904 A/T cg04320760 chr10:75533139 FUT11 -0.3 -4.67 -0.39 7.79e-6 Inflammatory bowel disease; TGCT cis rs7226408 0.857 rs3967207 chr18:34474742 T/C cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs2197308 0.692 rs1904964 chr12:37933241 T/A cg26384229 chr12:38710491 ALG10B 0.87 7.85 0.58 1.7e-12 Morning vs. evening chronotype; TGCT cis rs951366 0.617 rs9438393 chr1:205782718 A/G cg17178900 chr1:205818956 PM20D1 0.66 9.33 0.64 5.29e-16 Menarche (age at onset); TGCT cis rs12765878 0.603 rs9420904 chr10:105666745 G/A cg11005552 chr10:105648138 OBFC1 -0.4 -6.2 -0.49 7.61e-9 Coronary artery disease; TGCT cis rs28595532 1.000 rs115915387 chr4:119640854 C/T cg11846333 chr4:119757529 SEC24D 0.92 4.59 0.38 1.07e-5 Cannabis dependence symptom count; TGCT cis rs6687430 0.526 rs12117392 chr1:10608583 T/C cg17425144 chr1:10567563 PEX14 0.51 5.81 0.46 4.89e-8 Hand grip strength; TGCT cis rs6141769 0.542 rs6057630 chr20:31318737 A/G cg13636640 chr20:31349939 DNMT3B -0.55 -4.62 -0.38 9.33e-6 Subjective well-being; TGCT cis rs9297145 0.565 rs56132062 chr7:98778198 C/T cg05967295 chr7:98741636 SMURF1 -0.68 -8.35 -0.6 1.12e-13 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs7829975 0.714 rs6994038 chr8:8660538 C/A cg08975724 chr8:8085496 FLJ10661 0.56 4.99 0.41 2.02e-6 Mood instability; TGCT cis rs9583531 0.574 rs61971615 chr13:111353111 C/T cg24331049 chr13:111365604 ING1 -0.83 -7.99 -0.58 8.11e-13 Coronary artery disease; TGCT cis rs2535633 0.602 rs2581816 chr3:53014657 C/T cg10802521 chr3:52805072 NEK4 -0.54 -5.75 -0.46 6.64e-8 Body mass index; TGCT cis rs7833790 0.632 rs6415653 chr8:82702536 A/G cg27398817 chr8:82754497 SNX16 -0.64 -4.91 -0.4 2.85e-6 Diastolic blood pressure; TGCT cis rs60843830 0.964 rs62114538 chr2:256116 G/T cg25945732 chr2:264204 ACP1;SH3YL1 0.7 7.1 0.54 8.5e-11 Spherical equivalent (joint analysis main effects and education interaction); TGCT cis rs2228479 0.850 rs11648433 chr16:89965055 G/A cg06558623 chr16:89946397 TCF25 0.57 6.52 0.51 1.62e-9 Skin colour saturation; TGCT cis rs7572263 0.959 rs6725512 chr2:209050418 A/G cg23998903 chr2:209048830 C2orf80 -0.32 -4.45 -0.37 1.87e-5 Glioma;Non-glioblastoma glioma; TGCT cis rs4631830 0.832 rs10825652 chr10:51510761 G/A cg10326726 chr10:51549505 MSMB 0.27 5.2 0.42 7.86e-7 Prostate-specific antigen levels; TGCT cis rs7192750 0.586 rs4788564 chr16:71891862 G/A cg06353428 chr16:71660113 MARVELD3 0.83 7.37 0.55 2.07e-11 LDL cholesterol levels;Total cholesterol levels; TGCT cis rs7412746 0.658 rs72704682 chr1:150897677 A/T cg04414720 chr1:150670196 GOLPH3L 0.37 4.46 0.37 1.81e-5 Melanoma; TGCT cis rs854765 0.604 rs12948749 chr17:17949802 G/A cg09796270 chr17:17721594 SREBF1 -0.28 -5.55 -0.45 1.64e-7 Total body bone mineral density; TGCT cis rs10028773 0.666 rs12498657 chr4:120262866 G/C cg09307838 chr4:120376055 NA 0.54 5.29 0.43 5.44e-7 Educational attainment; TGCT cis rs12579753 1.000 rs12579753 chr12:82219376 C/T cg07988820 chr12:82153109 PPFIA2 -0.59 -6.34 -0.49 3.91e-9 Resting heart rate; TGCT cis rs35160687 0.901 rs34069316 chr2:86529792 T/C cg03171300 chr2:86307199 POLR1A 0.32 5.57 0.45 1.48e-7 Night sleep phenotypes; TGCT cis rs7937682 0.881 rs4936678 chr11:111625085 C/T cg09085632 chr11:111637200 PPP2R1B 1.1 8.72 0.62 1.48e-14 Primary sclerosing cholangitis; TGCT cis rs4252435 0.520 rs7810229 chr7:142641087 A/G cg09833174 chr7:143059591 FAM131B 1.02 4.65 0.39 8.26e-6 Cancer; TGCT cis rs28595532 0.920 rs114080496 chr4:119726372 C/T cg14228332 chr4:119757509 SEC24D 1.38 6.93 0.53 2.07e-10 Cannabis dependence symptom count; TGCT cis rs7666738 0.830 rs13141752 chr4:98893128 G/A cg17366294 chr4:99064904 C4orf37 0.68 6.87 0.53 2.72e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs7666738 0.887 rs34509663 chr4:98982531 C/T cg05340658 chr4:99064831 C4orf37 0.49 4.88 0.4 3.14e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs4862750 0.832 rs9995958 chr4:187901764 G/A cg11301795 chr4:187892539 NA -0.3 -4.46 -0.37 1.83e-5 Lobe attachment (rater-scored or self-reported); TGCT cis rs11105298 0.891 rs1054807 chr12:89913419 C/T cg00757033 chr12:89920650 WDR51B 0.34 5.46 0.44 2.52e-7 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs6831352 0.589 rs1133483 chr4:100023923 G/C cg12011299 chr4:100065546 ADH4 0.39 5.71 0.46 7.97e-8 Alcohol dependence; TGCT cis rs7666738 0.830 rs13125930 chr4:98654695 G/A cg05340658 chr4:99064831 C4orf37 0.46 5.42 0.44 3.01e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs66573146 0.808 rs56268690 chr4:6923887 C/T cg01220768 chr4:7056774 TADA2B 0.32 4.56 0.38 1.21e-5 Granulocyte percentage of myeloid white cells; TGCT cis rs2153535 0.580 rs6597335 chr6:8527714 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.75 0.46 6.55e-8 Motion sickness; TGCT cis rs77948430 0.581 rs75036255 chr8:13156597 A/G cg25598624 chr8:12235727 FAM66A 0.31 4.53 0.38 1.36e-5 Itch intensity from mosquito bite adjusted by bite size; TGCT trans rs6089829 0.851 rs10854168 chr20:61669550 A/G cg13615516 chr5:77269221 NA 0.73 8.39 0.6 9.12e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs3845702 0.736 rs1904850 chr2:180852767 A/G cg01881094 chr2:180872142 CWC22 -1.05 -6.79 -0.52 4.16e-10 Schizophrenia; TGCT cis rs4665809 1.000 rs4665298 chr2:26256378 G/A cg04944784 chr2:26401820 FAM59B -0.65 -5.87 -0.47 3.8e-8 Gut microbiome composition (summer); TGCT cis rs9467711 0.516 rs1165168 chr6:25859508 A/C cg03264133 chr6:25882463 NA -0.67 -4.47 -0.37 1.76e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs11098499 0.754 rs34425882 chr4:120253177 G/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9393777 0.920 rs35768595 chr6:27141904 C/T cg16898833 chr6:26189333 HIST1H4D 1.29 5.83 0.46 4.6e-8 Intelligence (multi-trait analysis); TGCT cis rs854765 0.964 rs854764 chr17:18011750 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.64 -6.28 -0.49 5.2e-9 Total body bone mineral density; TGCT cis rs4654899 0.931 rs3125161 chr1:21126346 A/G cg01072550 chr1:21505969 NA 0.48 7.58 0.56 6.95e-12 Superior frontal gyrus grey matter volume; TGCT cis rs826838 1.000 rs7299124 chr12:39002661 T/C cg13010199 chr12:38710504 ALG10B 0.82 6.88 0.53 2.68e-10 Heart rate; TGCT cis rs7959452 0.590 rs11177628 chr12:69765421 G/A cg11871910 chr12:69753446 YEATS4 0.82 8.82 0.62 8.61e-15 Blood protein levels; TGCT cis rs17376456 0.825 rs10057130 chr5:93282557 C/T cg25358565 chr5:93447407 FAM172A 1.02 8.11 0.59 4.23e-13 Diabetic retinopathy; TGCT cis rs7582180 0.663 rs10199518 chr2:100946041 G/A cg08017756 chr2:100939284 LONRF2 -0.3 -5.0 -0.41 1.93e-6 Intelligence (multi-trait analysis); TGCT cis rs4794106 0.792 rs11365 chr17:48211533 T/G cg13127421 chr17:48202128 SAMD14 -0.26 -6.5 -0.5 1.74e-9 Temporomandibular joint disorder; TGCT cis rs10504229 1.000 rs59549824 chr8:58186205 A/C cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs78487399 0.908 rs72868636 chr2:43838516 T/G cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.62 4.5 0.37 1.56e-5 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs9311474 0.967 rs11717383 chr3:52287468 G/T cg10802521 chr3:52805072 NEK4 -0.56 -6.25 -0.49 6.16e-9 Electroencephalogram traits; TGCT cis rs1865760 0.532 rs1061482 chr6:26086699 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.51 0.56 9.98e-12 Height; TGCT cis rs6125597 0.967 rs6063380 chr20:47881581 A/C cg11220565 chr20:47934802 NA -0.3 -4.61 -0.38 9.8e-6 Intelligence (multi-trait analysis); TGCT cis rs9611565 0.546 rs2092274 chr22:42123737 A/G cg17554472 chr22:41940697 POLR3H 0.48 5.17 0.42 9e-7 Vitiligo; TGCT trans rs11082438 1.000 rs11082438 chr18:42865210 G/T cg13513804 chr10:50121894 LRRC18;WDFY4 -0.73 -6.64 -0.51 9e-10 Follicular lymphoma; TGCT cis rs2067615 0.579 rs7964605 chr12:107205413 C/T cg15890332 chr12:107067104 RFX4 -0.28 -5.64 -0.45 1.1e-7 Heart rate; TGCT cis rs6598955 0.724 rs7526545 chr1:26569990 C/A cg04990556 chr1:26633338 UBXN11 -0.91 -11.99 -0.73 1.8e-22 Obesity-related traits; TGCT cis rs9341808 0.791 rs1324122 chr6:80946061 G/A cg08355045 chr6:80787529 NA 0.29 5.1 0.42 1.23e-6 Sitting height ratio; TGCT cis rs10479542 0.752 rs7704349 chr5:178986978 C/G cg26516362 chr5:178986906 RUFY1 -0.42 -4.58 -0.38 1.1e-5 Lung cancer; TGCT cis rs2486288 0.656 rs11637364 chr15:45579238 C/T cg26924012 chr15:45694286 SPATA5L1 -0.81 -8.5 -0.61 5.18e-14 Glomerular filtration rate; TGCT cis rs1008375 1.000 rs2109522 chr4:17658645 T/A cg18681998 chr4:17616180 MED28 1.01 11.89 0.73 3.17e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs2120019 1.000 rs12324912 chr15:75361006 G/A cg11632617 chr15:75315747 PPCDC -0.33 -4.63 -0.38 9.1e-6 Blood trace element (Zn levels); TGCT cis rs7211079 0.843 rs73438138 chr17:78122407 T/G cg09238746 chr17:78121135 EIF4A3 -0.7 -5.82 -0.46 4.79e-8 Myocardial infarction; TGCT cis rs4074961 0.585 rs10752600 chr1:38067552 G/T cg11397548 chr1:38022522 DNALI1 0.44 5.05 0.41 1.51e-6 Axial length; TGCT cis rs8031584 0.697 rs798080 chr15:31122169 T/C cg08704250 chr15:31115839 NA 0.44 6.46 0.5 2.18e-9 Huntington's disease progression; TGCT cis rs2948294 0.545 rs11776397 chr8:8115161 C/T cg15556689 chr8:8085844 FLJ10661 0.78 6.78 0.52 4.31e-10 Red cell distribution width; TGCT cis rs9443645 0.869 rs9343863 chr6:79752792 T/C cg09184832 chr6:79620586 NA -0.48 -5.34 -0.43 4.21e-7 Intelligence (multi-trait analysis); TGCT cis rs2836950 0.565 rs8131132 chr21:40538256 T/C cg11644478 chr21:40555479 PSMG1 -0.53 -4.98 -0.41 2.07e-6 Menarche (age at onset); TGCT cis rs9399137 0.507 rs6918512 chr6:135284839 T/G cg24558204 chr6:135376177 HBS1L 0.47 4.78 0.39 4.95e-6 Glycated hemoglobin levels;Mean corpuscular volume;Hematology traits;HbA2 levels;Mean corpuscular hemoglobin;Hemoglobin levels;F-cell distribution;Platelet count; TGCT cis rs9674544 0.556 rs1390154 chr17:47071483 A/G cg07075026 chr17:47091521 IGF2BP1 -0.49 -5.24 -0.43 6.68e-7 Primary tooth development (time to first tooth eruption);Primary tooth development (number of teeth); TGCT cis rs9914988 0.943 rs9893782 chr17:27108132 C/T cg20469991 chr17:27169893 C17orf63 -0.72 -5.04 -0.41 1.58e-6 High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells;Glycated hemoglobin levels; TGCT cis rs10504229 0.953 rs75545548 chr8:58172816 T/C cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs7584330 0.518 rs74478860 chr2:238437364 C/G cg14458575 chr2:238380390 NA 0.43 4.55 0.38 1.25e-5 Prostate cancer; TGCT cis rs425277 1.000 rs262641 chr1:2104981 C/T cg24578937 chr1:2090814 PRKCZ -0.3 -7.61 -0.56 5.87e-12 Height; TGCT cis rs17376456 0.569 rs7702348 chr5:93065683 A/G cg25358565 chr5:93447407 FAM172A -0.76 -6.61 -0.51 1.01e-9 Diabetic retinopathy; TGCT cis rs11098499 0.779 rs6815934 chr4:120267310 T/C cg09307838 chr4:120376055 NA 0.56 5.5 0.44 2.08e-7 Corneal astigmatism; TGCT cis rs6089584 1.000 rs6089583 chr20:60563624 G/A cg06108461 chr20:60628389 TAF4 -0.57 -8.01 -0.58 7.25e-13 Body mass index; TGCT cis rs8014204 0.762 rs2359237 chr14:75245002 G/A cg06637938 chr14:75390232 RPS6KL1 0.58 5.13 0.42 1.11e-6 Caffeine consumption; TGCT cis rs3761847 0.622 rs1323471 chr9:123826315 C/T cg09419670 chr9:123605666 PSMD5;LOC253039 0.43 4.52 0.38 1.42e-5 Rheumatoid arthritis; TGCT cis rs826838 0.967 rs1719854 chr12:39127707 G/A cg13010199 chr12:38710504 ALG10B -0.63 -5.06 -0.41 1.46e-6 Heart rate; TGCT cis rs7666738 0.830 rs58367603 chr4:99015350 T/C cg05340658 chr4:99064831 C4orf37 0.48 5.43 0.44 2.92e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs7208859 0.623 rs3752019 chr17:29151705 C/T cg14008862 chr17:28927542 LRRC37B2 0.75 5.06 0.41 1.5e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs981844 0.712 rs4525952 chr4:154746606 G/T cg14289246 chr4:154710475 SFRP2 1.02 8.96 0.63 4.03e-15 Response to statins (LDL cholesterol change); TGCT cis rs11148252 0.538 rs2296349 chr13:52710058 T/G cg00495681 chr13:53174319 NA 0.57 5.86 0.47 3.84e-8 Lewy body disease; TGCT cis rs40363 0.645 rs250629 chr16:3525431 C/A cg21433313 chr16:3507492 NAT15 0.36 4.63 0.38 8.91e-6 Tuberculosis; TGCT cis rs11763147 1 rs11763147 chr7:65326821 C/T cg18876405 chr7:65276391 NA -0.35 -5.54 -0.45 1.77e-7 Corneal structure; TGCT trans rs561341 0.883 rs72821942 chr17:30234460 C/T cg20587970 chr11:113659929 NA -0.82 -9.83 -0.66 3.19e-17 Hip circumference adjusted for BMI; TGCT cis rs765787 0.530 rs4775836 chr15:45537664 T/C cg24006582 chr15:45444508 DUOX1 -0.25 -5.54 -0.45 1.76e-7 Uric acid levels; TGCT cis rs9818758 0.607 rs61729488 chr3:49067904 T/C cg00383909 chr3:49044727 WDR6 1.38 7.1 0.54 8.45e-11 High light scatter reticulocyte percentage of red cells;Reticulocyte fraction of red cells;Reticulocyte count;Glycated hemoglobin levels; TGCT cis rs13217239 0.574 rs9366680 chr6:27006123 A/T cg05738196 chr6:26577821 NA 0.46 4.5 0.37 1.53e-5 Schizophrenia; TGCT cis rs12762955 0.519 rs7094331 chr10:1022816 T/C cg26597838 chr10:835615 NA -0.43 -5.8 -0.46 5.31e-8 Response to angiotensin II receptor blocker therapy; TGCT cis rs7542091 0.704 rs7537294 chr1:210043777 A/G cg23283495 chr1:209979779 IRF6 0.55 5.47 0.44 2.34e-7 Monobrow; TGCT cis rs2742417 0.603 rs2064064 chr3:45759995 C/T cg04837898 chr3:45731254 SACM1L -0.66 -7.02 -0.53 1.27e-10 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs7089973 0.604 rs11196932 chr10:116584386 C/T cg03647239 chr10:116582469 FAM160B1 0.58 5.63 0.45 1.16e-7 Bipolar disorder or attention deficit hyperactivity disorder; TGCT cis rs910316 1.000 rs10142865 chr14:75555624 G/A cg08847533 chr14:75593920 NEK9 0.96 10.9 0.7 8.37e-20 Height; TGCT cis rs2032447 0.772 rs199754 chr6:25992309 A/G cg07061783 chr6:25882402 NA -0.56 -5.52 -0.44 1.86e-7 Intelligence (multi-trait analysis); TGCT cis rs6696846 0.630 rs6692706 chr1:205158561 G/T cg00857998 chr1:205179979 DSTYK 0.48 4.44 0.37 1.93e-5 Red blood cell count; TGCT cis rs35306767 0.903 rs1341741 chr10:888073 A/G cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs10089 1.000 rs17164310 chr5:127493679 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 0.85 8.15 0.59 3.35e-13 Ileal carcinoids; TGCT cis rs4862750 0.914 rs9995391 chr4:187873749 A/T cg10295955 chr4:187884368 NA 0.82 8.68 0.61 1.85e-14 Lobe attachment (rater-scored or self-reported); TGCT cis rs10256972 0.552 rs2960831 chr7:1201192 A/T cg18402987 chr7:1209562 NA 0.39 5.03 0.41 1.64e-6 Longevity;Endometriosis; TGCT cis rs2243480 1.000 rs2177703 chr7:65391717 C/A cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs7618915 0.547 rs62255362 chr3:52699741 C/G cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs208520 0.633 rs7738469 chr6:66807446 T/C cg07460842 chr6:66804631 NA -0.94 -9.83 -0.66 3.3e-17 Exhaled nitric oxide output; TGCT cis rs4252435 0.614 rs11976316 chr7:142600456 T/G cg09833174 chr7:143059591 FAM131B -0.96 -4.52 -0.38 1.41e-5 Cancer; TGCT cis rs1205863 1.000 rs1205856 chr6:11942728 C/T cg07106625 chr6:11870215 NA 0.51 5.05 0.41 1.51e-6 Disc degeneration (lumbar); TGCT cis rs4665809 0.531 rs12987980 chr2:26462093 A/T cg22920501 chr2:26401640 FAM59B 0.81 6.36 0.5 3.52e-9 Gut microbiome composition (summer); TGCT cis rs80282103 0.618 rs1079390 chr10:1161653 C/A cg18964960 chr10:1102726 WDR37 1.03 4.55 0.38 1.28e-5 Glomerular filtration rate (creatinine); TGCT trans rs28735056 0.818 rs7235615 chr18:77644742 C/T cg05926928 chr17:57297772 GDPD1 0.65 6.87 0.53 2.7e-10 Schizophrenia; TGCT cis rs9486715 0.867 rs2223238 chr6:96871855 G/A cg06623918 chr6:96969491 KIAA0776 1.11 16.62 0.83 2.35e-33 Headache; TGCT cis rs8017423 0.630 rs4904678 chr14:90821670 T/C cg04374321 chr14:90722782 PSMC1 -0.54 -5.41 -0.44 3.13e-7 Mortality in heart failure; TGCT cis rs61990749 0.597 rs176943 chr14:78175797 T/G cg23188588 chr14:78226832 SNW1;C14orf178 -0.67 -4.73 -0.39 6.09e-6 Fibroblast growth factor basic levels; TGCT trans rs877282 0.898 rs12354872 chr10:763362 G/A cg22713356 chr15:30763199 NA 1.2 9.16 0.64 1.36e-15 Uric acid levels; TGCT trans rs1814175 0.791 rs10769593 chr11:49616217 T/C cg03929089 chr4:120376271 NA -0.74 -8.95 -0.63 4.41e-15 Height; TGCT cis rs6570726 0.935 rs382910 chr6:145865941 G/A cg23711669 chr6:146136114 FBXO30 0.7 6.78 0.52 4.39e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs12188164 0.840 rs67665078 chr5:428754 G/A cg26850624 chr5:429559 AHRR -0.18 -4.47 -0.37 1.74e-5 Cystic fibrosis severity; TGCT trans rs629535 0.814 rs56326813 chr8:70107736 T/A cg21567404 chr3:27674614 NA -0.57 -8.89 -0.62 6.09e-15 Dupuytren's disease; TGCT cis rs4664308 0.870 rs1870104 chr2:161032285 A/G cg03641300 chr2:160917029 PLA2R1 -0.28 -6.9 -0.53 2.38e-10 Idiopathic membranous nephropathy; TGCT cis rs7917772 0.582 rs4919665 chr10:104366042 C/T cg11453585 chr10:104263688 ACTR1A;SUFU -0.55 -5.36 -0.43 3.84e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs6460942 0.915 rs7802454 chr7:12454508 A/G cg06484146 chr7:12443880 VWDE -0.57 -5.52 -0.44 1.92e-7 Coronary artery disease; TGCT cis rs12188164 0.686 rs72711370 chr5:421057 A/C cg22025206 chr5:502436 SLC9A3 -0.26 -4.57 -0.38 1.18e-5 Cystic fibrosis severity; TGCT cis rs10504229 0.639 rs67996345 chr8:58117127 A/G cg08280861 chr8:58055591 NA 0.4 4.73 0.39 5.97e-6 Developmental language disorder (linguistic errors); TGCT cis rs2302063 0.627 rs1682802 chr19:3158116 C/G cg20125501 chr19:3176608 NA -0.26 -4.75 -0.39 5.42e-6 Glucose homeostasis traits; TGCT cis rs6977660 0.714 rs10251774 chr7:19790489 T/C cg07541023 chr7:19748670 TWISTNB 0.85 4.84 0.4 3.74e-6 Thyroid stimulating hormone; TGCT cis rs6951245 0.935 rs76525951 chr7:1096013 C/T cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs11190604 1.000 rs2495755 chr10:102324649 A/C cg16342193 chr10:102329863 NA -0.42 -5.26 -0.43 5.99e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs10256972 0.552 rs6978842 chr7:1204599 A/C cg07092213 chr7:1199455 ZFAND2A -0.49 -5.58 -0.45 1.45e-7 Longevity;Endometriosis; TGCT cis rs9611565 0.659 rs12484694 chr22:41919330 A/G cg03806693 chr22:41940476 POLR3H -1.12 -13.03 -0.76 5.66e-25 Vitiligo; TGCT cis rs259282 0.605 rs2302970 chr19:33098632 G/C cg27413643 chr19:33165484 ANKRD27;RGS9BP 0.61 5.42 0.44 2.93e-7 Schizophrenia; TGCT cis rs11105298 0.891 rs10858903 chr12:89927972 G/A cg08166232 chr12:89918718 WDR51B;GALNT4 -0.7 -5.12 -0.42 1.12e-6 B-type natriuretic peptide to N-terminal pro B-type natriuretic peptide ratio; TGCT cis rs9611565 0.840 rs2234052 chr22:41777241 A/G cg06634786 chr22:41940651 POLR3H -0.86 -8.32 -0.6 1.34e-13 Vitiligo; TGCT cis rs17221829 0.733 rs72971005 chr11:89358412 G/A cg02982614 chr11:89391479 FOLH1B -0.26 -4.65 -0.39 8.43e-6 Anxiety in major depressive disorder; TGCT cis rs9814567 1.000 rs7637227 chr3:134244155 G/A cg06109529 chr3:134205091 CEP63;ANAPC13 -0.92 -8.76 -0.62 1.21e-14 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs8177179 0.967 rs9869311 chr3:133451613 C/T cg24879335 chr3:133465180 TF 0.37 5.02 0.41 1.72e-6 Iron status biomarkers (transferrin levels); TGCT cis rs13118159 0.550 rs1137789 chr4:1381798 A/G cg02018176 chr4:1364513 KIAA1530 0.26 4.48 0.37 1.68e-5 Longevity; TGCT cis rs9297145 0.509 rs13222381 chr7:98785024 T/G cg05967295 chr7:98741636 SMURF1 -0.68 -8.29 -0.6 1.54e-13 Crohn's disease;Inflammatory bowel disease;Ulcerative colitis; TGCT cis rs7726839 0.540 rs4957083 chr5:659343 T/C cg20362242 chr5:692897 TPPP 0.51 4.49 0.37 1.61e-5 Obesity-related traits; TGCT cis rs6952808 0.756 rs12537348 chr7:1948172 C/G cg22963979 chr7:1858916 MAD1L1 -0.35 -5.43 -0.44 2.85e-7 Bipolar disorder and schizophrenia; TGCT cis rs6433857 0.505 rs12471899 chr2:181369856 C/T cg23363182 chr2:181467187 NA -0.3 -4.57 -0.38 1.17e-5 Body mass index; TGCT cis rs2637266 0.745 rs2579733 chr10:78441896 C/T cg18941641 chr10:78392320 NA -0.36 -4.64 -0.38 8.6e-6 Pulmonary function; TGCT cis rs9948 0.655 rs17119564 chr2:97384728 G/A cg01990225 chr2:97406019 LMAN2L -1.01 -5.14 -0.42 1.02e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs9325144 0.671 rs12818797 chr12:39019409 A/G cg26384229 chr12:38710491 ALG10B -0.6 -5.76 -0.46 6.3e-8 Morning vs. evening chronotype; TGCT cis rs6570726 0.935 rs906774 chr6:145813770 T/C cg23711669 chr6:146136114 FBXO30 0.73 7.04 0.53 1.16e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs10791097 0.608 rs12363140 chr11:130744268 A/C cg12179176 chr11:130786555 SNX19 0.84 10.17 0.67 4.95e-18 Autism spectrum disorder or schizophrenia;Schizophrenia; TGCT cis rs7110818 0.510 rs3862807 chr11:76283081 C/T cg17647271 chr11:76299819 NA 0.38 4.55 0.38 1.26e-5 Gut microbiota (functional units); TGCT cis rs4434138 0.683 rs13063160 chr3:52602274 T/C cg11041457 chr3:52719354 GNL3;PBRM1 0.64 6.18 0.49 8.32e-9 Intelligence (multi-trait analysis); TGCT cis rs10504229 0.953 rs115634610 chr8:58190533 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs6882046 0.513 rs42850 chr5:88019474 G/A cg22951263 chr5:87985283 NA -0.58 -6.18 -0.49 8.49e-9 Intelligence (multi-trait analysis);Educational attainment (years of education);Neuroticism;Educational attainment (college completion);Educational attainment; TGCT cis rs10504229 0.728 rs59266065 chr8:58156236 A/G cg21724239 chr8:58056113 NA 0.41 4.97 0.41 2.19e-6 Developmental language disorder (linguistic errors); TGCT cis rs9926296 0.656 rs2376884 chr16:89826922 C/T cg27121462 chr16:89883253 FANCA 0.54 4.97 0.41 2.14e-6 Vitiligo; TGCT cis rs7666738 0.830 rs10031190 chr4:98908683 C/A cg18180107 chr4:99064573 C4orf37 0.55 5.06 0.41 1.44e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs1862618 0.713 rs832550 chr5:56182589 C/T cg18230493 chr5:56204884 C5orf35 -0.68 -5.85 -0.46 4.13e-8 Initial pursuit acceleration; TGCT trans rs6561151 0.681 rs2121037 chr13:44471317 C/T cg12856521 chr11:46389249 DGKZ 0.67 6.65 0.51 8.39e-10 Crohn's disease; TGCT cis rs9486719 0.843 rs3860229 chr6:97036559 T/C cg18709589 chr6:96969512 KIAA0776 -0.78 -6.38 -0.5 3.24e-9 Migraine;Coronary artery disease; TGCT cis rs6088590 1.000 rs910870 chr20:33292893 T/C cg24642439 chr20:33292090 TP53INP2 0.62 5.75 0.46 6.6e-8 Coronary artery disease; TGCT cis rs986417 0.818 rs10143831 chr14:61081961 G/T cg27398547 chr14:60952738 C14orf39 1.33 9.79 0.66 4e-17 Gut microbiota (bacterial taxa); TGCT cis rs2361710 0.668 rs2304855 chr17:78118266 T/A cg09238746 chr17:78121135 EIF4A3 -0.79 -7.49 -0.56 1.13e-11 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count;Immature fraction of reticulocytes; TGCT cis rs12701220 0.901 rs12701713 chr7:1090505 G/A cg07217954 chr7:1067459 C7orf50 -0.48 -4.72 -0.39 6.33e-6 Bronchopulmonary dysplasia; TGCT cis rs28386778 0.897 rs7221853 chr17:61859836 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs7635838 0.859 rs7632040 chr3:11427455 A/G cg00170343 chr3:11313890 ATG7 0.65 6.23 0.49 6.68e-9 HDL cholesterol; TGCT cis rs9435341 0.965 rs2335104 chr1:107583641 A/T cg09367891 chr1:107599246 PRMT6 0.66 5.85 0.47 4.04e-8 Facial morphology (factor 21, depth of nasal alae); TGCT cis rs7582180 0.629 rs11686799 chr2:100956055 C/G cg08017756 chr2:100939284 LONRF2 -0.3 -4.87 -0.4 3.27e-6 Intelligence (multi-trait analysis); TGCT cis rs6912958 0.500 rs4707352 chr6:87929705 G/A cg08069147 chr6:88032118 GJB7;C6orf162 -0.68 -7.03 -0.53 1.2e-10 Monocyte percentage of white cells; TGCT cis rs68170813 0.559 rs76933738 chr7:106814574 T/C cg02696742 chr7:106810147 HBP1 -0.72 -6.28 -0.49 5.29e-9 Coronary artery disease; TGCT cis rs10927875 0.757 rs4661679 chr1:16321010 C/T cg22431228 chr1:16359049 CLCNKA -0.24 -4.64 -0.38 8.71e-6 Dilated cardiomyopathy; TGCT cis rs4074961 0.509 rs4653300 chr1:38024054 A/G cg17933807 chr1:38061675 GNL2 1.01 16.04 0.82 5.04e-32 Axial length; TGCT cis rs1799949 0.965 rs34616041 chr17:41188786 G/A cg05368731 chr17:41323189 NBR1 1.08 11.0 0.7 4.76e-20 Menopause (age at onset); TGCT cis rs6500602 0.701 rs8129 chr16:4562351 A/G cg06139259 chr16:4526053 HMOX2;NMRAL1 0.26 4.81 0.4 4.3e-6 Schizophrenia; TGCT cis rs10479542 0.784 rs7702303 chr5:178986436 G/A cg00080972 chr5:178986291 RUFY1 0.59 7.77 0.57 2.62e-12 Lung cancer; TGCT cis rs916888 0.773 rs9896243 chr17:44826056 C/G cg17911788 chr17:44343683 NA -0.67 -7.15 -0.54 6.59e-11 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs2456568 0.835 rs1518578 chr11:93656854 G/T cg17595323 chr11:93583763 C11orf90 -0.49 -6.23 -0.49 6.65e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs10504229 0.683 rs17194792 chr8:58107195 A/C cg08219700 chr8:58056026 NA 0.39 4.73 0.39 5.99e-6 Developmental language disorder (linguistic errors); TGCT cis rs669446 0.561 rs516921 chr1:44081762 T/G cg12908607 chr1:44402522 ARTN -0.6 -5.73 -0.46 7.06e-8 Amyotrophic lateral sclerosis (age of onset); TGCT cis rs35306767 0.903 rs13377166 chr10:886259 G/A cg26597838 chr10:835615 NA 0.71 10.12 0.67 6.47e-18 Eosinophil percentage of granulocytes; TGCT cis rs28595532 0.764 rs115298416 chr4:119565383 C/T cg14228332 chr4:119757509 SEC24D 1.04 5.37 0.43 3.8e-7 Cannabis dependence symptom count; TGCT cis rs9388451 0.839 rs3757217 chr6:126069636 G/C cg10911889 chr6:126070802 HEY2 0.57 6.06 0.48 1.51e-8 Brugada syndrome; TGCT cis rs933688 1.000 rs10073935 chr5:90742188 A/G cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.0 8.64 0.61 2.4e-14 Smoking behavior; TGCT cis rs12477438 0.520 rs2516827 chr2:99772565 C/T cg15544633 chr2:99771531 LIPT1;TSGA10 1.13 17.43 0.84 3.73e-35 Chronic sinus infection; TGCT cis rs4240897 0.935 rs4846082 chr1:12042443 C/T cg05523254 chr1:12040215 MFN2 0.46 4.48 0.37 1.69e-5 Tuberculosis; TGCT cis rs10504229 0.683 rs11775506 chr8:58133639 G/T cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs2842992 0.715 rs2277073 chr6:160182749 G/A cg11366901 chr6:160182831 ACAT2 1.03 6.92 0.53 2.14e-10 Age-related macular degeneration (geographic atrophy); TGCT cis rs7296418 0.885 rs1790104 chr12:123709409 C/T cg00376283 chr12:123451042 ABCB9 0.84 7.67 0.57 4.4e-12 Platelet count; TGCT cis rs56104184 0.578 rs7254608 chr19:49395774 G/T cg11637076 chr19:49575188 KCNA7 -0.44 -5.23 -0.43 6.99e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs1799949 0.965 rs6503727 chr17:41312859 C/T cg23758822 chr17:41437982 NA 0.69 6.97 0.53 1.66e-10 Menopause (age at onset); TGCT cis rs9303401 0.625 rs66508449 chr17:56691034 T/C cg10487724 chr17:56770010 TEX14;RAD51C 0.7 6.65 0.51 8.41e-10 Cognitive test performance; TGCT cis rs77861329 1.000 rs352147 chr3:52208285 A/G cg08692210 chr3:52188851 WDR51A 0.94 4.83 0.4 3.91e-6 Macrophage inflammatory protein 1b levels; TGCT cis rs9527 0.615 rs10883811 chr10:104727279 A/G cg04362960 chr10:104952993 NT5C2 0.66 5.55 0.45 1.66e-7 Arsenic metabolism; TGCT cis rs317689 0.513 rs529268 chr12:69687051 G/A cg14784868 chr12:69753453 YEATS4 0.66 6.45 0.5 2.31e-9 Response to diuretic therapy; TGCT cis rs763121 0.925 rs5757165 chr22:38994577 C/T cg06022373 chr22:39101656 GTPBP1 0.79 7.98 0.58 8.44e-13 Menopause (age at onset); TGCT cis rs40363 0.645 rs1690449 chr16:3520893 C/G cg05754148 chr16:3507555 NAT15 0.4 4.71 0.39 6.65e-6 Tuberculosis; TGCT cis rs11785400 1.000 rs13266249 chr8:143732433 A/C cg10596483 chr8:143751796 JRK 0.54 5.77 0.46 5.95e-8 Schizophrenia; TGCT cis rs13108904 0.870 rs13124876 chr4:1247955 T/C cg05665937 chr4:1216051 CTBP1 0.26 5.05 0.41 1.54e-6 Obesity-related traits; TGCT cis rs9611565 0.559 rs739136 chr22:42100275 C/T cg06481639 chr22:41940642 POLR3H -0.71 -6.43 -0.5 2.56e-9 Vitiligo; TGCT cis rs9362426 1.000 rs9362426 chr6:88089874 A/G cg12350822 chr6:88032061 C6orf162;GJB7 0.46 5.23 0.43 6.86e-7 Depressive episodes in bipolar disorder; TGCT cis rs801193 0.967 rs2707853 chr7:66214010 G/A cg00343986 chr7:65444356 GUSB 0.24 5.26 0.43 6.15e-7 Aortic root size; TGCT cis rs7666738 0.546 rs10025064 chr4:98914060 A/G cg17366294 chr4:99064904 C4orf37 0.64 5.88 0.47 3.54e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs35306767 0.903 rs7067865 chr10:908387 C/T cg20503657 chr10:835505 NA 0.75 10.41 0.68 1.3e-18 Eosinophil percentage of granulocytes; TGCT cis rs11264213 0.901 rs794222 chr1:36369024 T/C cg07093915 chr1:36184400 C1orf216 0.66 4.47 0.37 1.73e-5 Schizophrenia; TGCT cis rs1997103 0.911 rs6949931 chr7:55391081 T/C cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs2050392 0.517 rs2480299 chr10:30743197 G/A cg18806716 chr10:30721971 MAP3K8 -0.46 -5.41 -0.44 3.1e-7 Inflammatory bowel disease; TGCT cis rs7216064 0.953 rs12601759 chr17:65955284 A/G cg12091567 chr17:66097778 LOC651250 -0.82 -6.2 -0.49 7.54e-9 Lung adenocarcinoma;Lung cancer;EGFR mutation-positive lung adenocarcinoma; TGCT cis rs11239930 0.538 rs56060937 chr1:146555403 G/A cg00044796 chr1:146552390 NA -0.34 -4.46 -0.37 1.84e-5 AIDS progression; TGCT cis rs514406 0.893 rs2897561 chr1:53388747 C/A cg08736216 chr1:53307985 ZYG11A -0.29 -6.09 -0.48 1.32e-8 Monocyte count; TGCT cis rs114540395 0.858 rs76838593 chr10:103143264 T/G cg18276125 chr10:102749041 C10orf2 0.38 4.6 0.38 1.05e-5 Schizophrenia; TGCT cis rs3806843 0.520 rs246051 chr5:140326464 G/A cg07102913 chr5:140593443 PCDHB13 -0.47 -4.7 -0.39 6.77e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs8031584 0.678 rs4779790 chr15:31164595 T/C cg14829155 chr15:31115871 NA -0.36 -4.72 -0.39 6.14e-6 Huntington's disease progression; TGCT cis rs4862750 0.832 rs6836426 chr4:187897837 T/G cg03452623 chr4:187889614 NA -0.36 -5.19 -0.42 8.48e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs7618915 0.547 rs13085895 chr3:52678270 G/C cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs3008870 1.000 rs2815348 chr1:67472165 G/C cg11518657 chr1:67396239 MIER1 0.54 4.61 0.38 9.72e-6 Lymphocyte percentage of white cells; TGCT cis rs10875746 0.669 rs11168459 chr12:48596241 A/G cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT trans rs7819412 0.765 rs17783634 chr8:11054097 C/A cg15556689 chr8:8085844 FLJ10661 -0.74 -6.96 -0.53 1.79e-10 Triglycerides; TGCT cis rs77106637 0.860 rs11603334 chr11:72432985 G/A cg03713592 chr11:72463424 ARAP1 1.21 9.04 0.63 2.56e-15 Type 2 diabetes; TGCT cis rs910316 1.000 rs175426 chr14:75624134 C/T cg08847533 chr14:75593920 NEK9 -0.95 -10.32 -0.68 2.09e-18 Height; TGCT cis rs2997447 0.595 rs3008425 chr1:26385660 T/C cg19633962 chr1:26362018 EXTL1 -0.65 -4.7 -0.39 6.74e-6 QRS complex (12-leadsum); TGCT cis rs4409675 0.576 rs2749119 chr1:28236248 G/A cg23691781 chr1:28212827 C1orf38 0.26 5.44 0.44 2.76e-7 Corneal astigmatism; TGCT cis rs8067545 0.750 rs888423 chr17:19999409 G/A cg13482628 chr17:19912719 NA 0.53 4.55 0.38 1.25e-5 Schizophrenia; TGCT cis rs28493229 0.500 rs45545932 chr19:41190875 G/A cg11601297 chr19:41224147 ITPKC;ADCK4 0.5 5.02 0.41 1.75e-6 Kawasaki disease; TGCT cis rs854765 0.964 rs12950562 chr17:17995166 C/T cg04398451 chr17:18023971 MYO15A 0.3 4.67 0.39 7.62e-6 Total body bone mineral density; TGCT cis rs9611565 0.649 rs79009 chr22:41860864 C/A cg06634786 chr22:41940651 POLR3H 0.87 8.25 0.6 1.92e-13 Vitiligo; TGCT cis rs2742234 1.000 rs1864399 chr10:43610455 T/C cg02780029 chr10:43622663 RET -0.25 -4.82 -0.4 4.06e-6 Hirschsprung disease; TGCT cis rs116095464 0.558 rs10462755 chr5:246748 T/C cg22857025 chr5:266934 NA -0.34 -6.72 -0.52 5.96e-10 Breast cancer; TGCT cis rs12478296 1.000 rs12478296 chr2:243048760 A/G cg06360820 chr2:242988706 NA 0.58 4.62 0.38 9.38e-6 Obesity-related traits; TGCT cis rs916888 0.647 rs199449 chr17:44808902 G/A cg17911788 chr17:44343683 NA -0.5 -5.73 -0.46 7.09e-8 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7100689 0.556 rs3120976 chr10:82025682 C/A cg01528321 chr10:82214614 TSPAN14 0.7 6.82 0.52 3.53e-10 Post bronchodilator FEV1; TGCT cis rs7772486 0.754 rs9390358 chr6:146145678 C/T cg23711669 chr6:146136114 FBXO30 0.9 10.04 0.67 1e-17 Lobe attachment (rater-scored or self-reported); TGCT cis rs3784262 0.528 rs11071367 chr15:58354152 G/A cg12031962 chr15:58353849 ALDH1A2 0.38 5.56 0.45 1.55e-7 Barrett's esophagus;Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined); TGCT cis rs9325144 0.625 rs11534879 chr12:38968165 A/G cg26384229 chr12:38710491 ALG10B -0.59 -5.6 -0.45 1.28e-7 Morning vs. evening chronotype; TGCT cis rs9443645 0.869 rs9443621 chr6:79576499 A/G cg05283184 chr6:79620031 NA -0.22 -4.98 -0.41 2.11e-6 Intelligence (multi-trait analysis); TGCT cis rs514406 0.861 rs7526275 chr1:53245849 C/T cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT cis rs2440129 0.611 rs1126667 chr17:6902760 C/T cg03760483 chr17:6899297 ALOX12 -0.41 -4.89 -0.4 3.07e-6 Tonsillectomy; TGCT cis rs8017423 0.935 rs716122 chr14:90792313 A/C cg04374321 chr14:90722782 PSMC1 -0.74 -7.09 -0.54 8.75e-11 Mortality in heart failure; TGCT cis rs6089829 0.855 rs6062781 chr20:61667128 G/A cg08045932 chr20:61659980 NA 0.48 9.16 0.64 1.36e-15 Prostate cancer (SNP x SNP interaction); TGCT cis rs9309473 0.606 rs6759452 chr2:73878352 C/T cg07208825 chr2:73871855 ALMS1P 0.27 5.09 0.42 1.28e-6 Metabolite levels; TGCT cis rs2404602 0.692 rs12911174 chr15:77149943 G/A cg22467129 chr15:76604101 ETFA -0.46 -5.26 -0.43 5.99e-7 Blood metabolite levels; TGCT cis rs9393777 0.513 rs9393739 chr6:26646966 T/G cg18278486 chr6:26987575 LOC100270746;C6orf41 -0.63 -5.75 -0.46 6.58e-8 Intelligence (multi-trait analysis); TGCT cis rs7937682 0.587 rs611607 chr11:111349765 C/T cg09085632 chr11:111637200 PPP2R1B -0.63 -5.91 -0.47 3.12e-8 Primary sclerosing cholangitis; TGCT cis rs612683 0.524 rs479269 chr1:100887616 A/G cg06223162 chr1:101003688 GPR88 0.28 4.53 0.38 1.38e-5 Breast cancer; TGCT cis rs11122272 0.735 rs2486745 chr1:231505717 T/C cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.72 -7.14 -0.54 6.86e-11 Hemoglobin concentration; TGCT trans rs6561151 0.957 rs3764147 chr13:44457925 C/T cg12856521 chr11:46389249 DGKZ -0.62 -6.76 -0.52 4.79e-10 Crohn's disease; TGCT cis rs10883723 0.810 rs13287 chr10:104240438 A/G cg11453585 chr10:104263688 ACTR1A;SUFU 0.82 8.53 0.61 4.23e-14 Allergic disease (asthma, hay fever or eczema); TGCT cis rs2597513 1.000 rs2597513 chr3:13555836 C/T cg13071069 chr3:13005914 IQSEC1 -0.4 -4.51 -0.38 1.47e-5 Hip circumference adjusted for BMI;Height; TGCT cis rs1005277 0.579 rs2472181 chr10:38386764 T/C cg25427524 chr10:38739819 LOC399744 -0.39 -8.05 -0.59 5.9e-13 Extrinsic epigenetic age acceleration; TGCT cis rs6951245 1.000 rs113066613 chr7:1094128 T/C cg18402987 chr7:1209562 NA 0.81 6.94 0.53 1.9e-10 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs7523273 0.606 rs1962149 chr1:207956559 G/A cg22525895 chr1:207977042 MIR29B2 -0.52 -8.75 -0.62 1.28e-14 Schizophrenia; TGCT cis rs3806843 0.966 rs1030166 chr5:140185473 G/A cg19875535 chr5:140030758 IK 0.35 5.85 0.47 4.01e-8 Depressive symptoms (multi-trait analysis); TGCT cis rs7312933 0.703 rs10492388 chr12:42608001 T/C cg19980929 chr12:42632907 YAF2 0.46 6.1 0.48 1.24e-8 Plasma omega-6 polyunsaturated fatty acid levels (linoleic acid); TGCT cis rs514406 0.929 rs564273 chr1:53332445 G/C cg16325326 chr1:53192061 ZYG11B 0.63 6.94 0.53 1.92e-10 Monocyte count; TGCT cis rs8084125 0.832 rs62105179 chr18:74950858 A/G cg07390210 chr18:74961196 GALR1 0.37 4.51 0.38 1.49e-5 Obesity-related traits; TGCT cis rs2842992 0.692 rs1128661 chr6:160211554 T/G cg11366901 chr6:160182831 ACAT2 0.79 5.81 0.46 4.92e-8 Age-related macular degeneration (geographic atrophy); TGCT cis rs7666738 0.761 rs13136913 chr4:98998031 C/T cg17366294 chr4:99064904 C4orf37 0.69 7.03 0.53 1.21e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs2404602 0.647 rs116090606 chr15:77075209 A/G cg23625390 chr15:77176239 SCAPER -0.38 -4.81 -0.4 4.29e-6 Blood metabolite levels; TGCT cis rs854765 0.594 rs8066560 chr17:17728043 A/G cg09796270 chr17:17721594 SREBF1 -0.25 -4.79 -0.4 4.58e-6 Total body bone mineral density; TGCT cis rs854765 0.624 rs4925116 chr17:17731200 A/G cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.69 -6.52 -0.5 1.64e-9 Total body bone mineral density; TGCT cis rs28386778 0.897 rs8081454 chr17:61842646 A/G cg26338869 chr17:61819248 STRADA -0.53 -4.85 -0.4 3.68e-6 Prudent dietary pattern; TGCT cis rs1018836 0.631 rs61276517 chr8:91474406 A/G cg16814680 chr8:91681699 NA -0.75 -7.43 -0.56 1.5e-11 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs11711311 0.955 rs12630833 chr3:113390883 G/T cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.78 -6.77 -0.52 4.53e-10 IgG glycosylation; TGCT cis rs910316 0.737 rs91144 chr14:75449517 G/A cg11812906 chr14:75593930 NEK9 -0.58 -5.69 -0.45 8.69e-8 Height; TGCT cis rs7542091 0.669 rs11119357 chr1:210042382 C/T cg00989853 chr1:209979345 IRF6 0.43 4.57 0.38 1.18e-5 Monobrow; TGCT cis rs6429082 0.846 rs2270538 chr1:235602404 G/A cg26050004 chr1:235667680 B3GALNT2 -0.59 -4.95 -0.41 2.33e-6 Adiposity; TGCT cis rs9650657 0.515 rs7820860 chr8:10950396 C/G cg27411982 chr8:10470053 RP1L1 -0.21 -4.55 -0.38 1.29e-5 Neuroticism; TGCT cis rs225245 0.791 rs8067294 chr17:34027964 T/C cg05299278 chr17:33885742 SLFN14 0.21 4.5 0.37 1.54e-5 Reticulocyte count;Reticulocyte fraction of red cells;High light scatter reticulocyte count;High light scatter reticulocyte percentage of red cells; TGCT cis rs1008375 0.686 rs34338142 chr4:17626174 T/A cg18681998 chr4:17616180 MED28 1.07 11.45 0.72 3.83e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs7267979 0.934 rs2500399 chr20:25354694 T/G cg14121845 chr20:25566513 NINL -0.5 -5.44 -0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs11018874 0.597 rs10765243 chr11:89855118 C/G cg05041596 chr11:89867385 NAALAD2 0.5 4.89 0.4 3.07e-6 White blood cell types; TGCT cis rs1990950 0.692 rs6868660 chr5:156860229 A/G cg25387487 chr5:157003181 ADAM19 0.29 4.53 0.38 1.37e-5 Lung function (FEV1/FVC); TGCT cis rs6964587 0.967 rs58673519 chr7:91823887 T/G cg22709100 chr7:91322751 NA 0.28 4.51 0.38 1.49e-5 Breast cancer; TGCT cis rs67311347 0.826 rs9863679 chr3:40439614 G/A cg13683864 chr3:40499215 RPL14 -1.19 -13.2 -0.76 2.17e-25 Renal cell carcinoma; TGCT cis rs10504229 1.000 rs77823122 chr8:58170161 A/G cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs7666738 0.753 rs13137152 chr4:98938044 A/T cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs514406 0.861 rs503015 chr1:53254456 T/C cg24675658 chr1:53192096 ZYG11B 0.7 7.98 0.58 8.59e-13 Monocyte count; TGCT trans rs4332037 0.615 rs62435127 chr7:1884937 A/G cg25206134 chr2:45395956 NA 0.93 7.88 0.58 1.43e-12 Bipolar disorder; TGCT cis rs7226408 0.857 rs7228810 chr18:34722050 A/G cg06757138 chr18:34340585 FHOD3 0.25 4.81 0.4 4.33e-6 Obesity-related traits; TGCT cis rs7914558 0.966 rs10748839 chr10:104953547 A/G cg04362960 chr10:104952993 NT5C2 0.62 5.53 0.44 1.8e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7659604 0.628 rs6838153 chr4:122720999 A/G cg19748678 chr4:122722346 EXOSC9 0.94 9.89 0.66 2.3e-17 Type 2 diabetes; TGCT cis rs28595532 0.841 rs116521340 chr4:119757415 C/A cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs2243480 0.711 rs1626926 chr7:65435792 C/T cg18252515 chr7:66147081 NA -1.2 -7.16 -0.54 6.16e-11 Diabetic kidney disease; TGCT cis rs57221529 0.709 rs72707024 chr5:667915 G/A cg20362242 chr5:692897 TPPP 0.52 4.69 0.39 7.16e-6 Lung disease severity in cystic fibrosis; TGCT cis rs9443645 0.869 rs9448591 chr6:79606490 C/T cg05283184 chr6:79620031 NA -0.21 -4.71 -0.39 6.61e-6 Intelligence (multi-trait analysis); TGCT cis rs7949030 0.523 rs12223627 chr11:62368557 G/C cg22862634 chr11:62369728 EML3;MTA2 0.6 6.0 0.47 2.04e-8 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs3796352 0.892 rs9756317 chr3:53088815 T/C cg07884673 chr3:53033167 SFMBT1 -0.58 -6.25 -0.49 5.99e-9 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10464366 0.544 rs1525799 chr7:39153131 C/G cg18850127 chr7:39170497 POU6F2 -0.32 -6.91 -0.53 2.28e-10 IgG glycosylation; TGCT cis rs6121246 0.609 rs6060652 chr20:30266845 A/G cg13852791 chr20:30311386 BCL2L1 0.84 8.15 0.59 3.38e-13 Mean corpuscular hemoglobin; TGCT cis rs7618915 0.571 rs33964154 chr3:52596914 A/G cg07507251 chr3:52567010 NT5DC2 0.48 6.95 0.53 1.82e-10 Bipolar disorder; TGCT cis rs2013441 0.932 rs3850782 chr17:20181940 A/C cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs3741404 0.931 rs594942 chr11:64006292 T/C cg03236948 chr11:63997492 DNAJC4 -0.36 -4.49 -0.37 1.6e-5 Platelet count; TGCT cis rs4819052 0.851 rs2330011 chr21:46658498 G/A cg19498844 chr21:46707878 POFUT2;LOC642852 0.7 6.24 0.49 6.19e-9 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs2032447 0.839 rs199750 chr6:26016462 A/G cg03264133 chr6:25882463 NA 0.64 5.89 0.47 3.34e-8 Intelligence (multi-trait analysis); TGCT cis rs1949733 0.816 rs2631746 chr4:8490934 C/T cg11789530 chr4:8429930 ACOX3 -0.52 -5.43 -0.44 2.87e-7 Response to antineoplastic agents; TGCT cis rs8177179 0.967 rs4443173 chr3:133439378 A/G cg16262614 chr3:133464971 TF 0.35 4.6 0.38 1.01e-5 Iron status biomarkers (transferrin levels); TGCT cis rs1215050 0.846 rs783923 chr4:98968686 C/T cg17366294 chr4:99064904 C4orf37 -0.47 -4.67 -0.39 7.61e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs763014 0.966 rs15564 chr16:677854 G/T cg00908189 chr16:619842 PIGQ 0.87 10.78 0.7 1.58e-19 Height; TGCT cis rs2997447 0.748 rs112813126 chr1:26432239 A/T cg03844060 chr1:26490628 NA 0.28 4.56 0.38 1.19e-5 QRS complex (12-leadsum); TGCT cis rs9311474 1.000 rs1060330 chr3:52288945 T/C cg07507251 chr3:52567010 NT5DC2 0.43 6.0 0.47 2e-8 Electroencephalogram traits; TGCT cis rs1799949 0.965 rs11657883 chr17:41330024 T/C cg10047753 chr17:41438598 NA 0.97 10.04 0.67 1.04e-17 Menopause (age at onset); TGCT cis rs9388451 0.868 rs10457467 chr6:126045148 T/A cg05901451 chr6:126070800 HEY2 -1.02 -13.72 -0.78 1.28e-26 Brugada syndrome; TGCT cis rs9443189 0.762 rs2748943 chr6:76435543 C/T cg01950844 chr6:76311363 SENP6 -0.66 -4.62 -0.38 9.55e-6 Prostate cancer; TGCT cis rs11785400 0.731 rs9720504 chr8:143725502 T/C cg24634471 chr8:143751801 JRK 0.53 5.33 0.43 4.41e-7 Schizophrenia; TGCT cis rs1552244 1.000 rs7626117 chr3:10140671 G/A cg18598329 chr3:10140678 FANCD2;C3orf24 -0.37 -5.82 -0.46 4.67e-8 Alzheimer's disease; TGCT cis rs2882877 0.560 rs11568351 chr2:190445194 C/G cg10752008 chr2:190445175 SLC40A1 -0.78 -6.26 -0.49 5.68e-9 Mean corpuscular hemoglobin concentration; TGCT cis rs7647973 0.710 rs9869120 chr3:49624065 T/C cg03060546 chr3:49711283 APEH 0.63 5.14 0.42 1.03e-6 Menarche (age at onset); TGCT cis rs4294134 0.608 rs35956223 chr7:135245054 C/T cg08396481 chr7:135194601 CNOT4 -0.62 -4.81 -0.4 4.25e-6 Paget's disease; TGCT cis rs7017914 0.967 rs7819332 chr8:71668265 G/C cg23757474 chr8:71581111 LACTB2;XKR9 -0.53 -4.9 -0.4 2.87e-6 Bone mineral density; TGCT cis rs9583531 0.550 rs7985098 chr13:111386416 G/A cg24331049 chr13:111365604 ING1 0.74 7.36 0.55 2.18e-11 Coronary artery disease; TGCT cis rs9916302 0.706 rs8067511 chr17:37611352 C/T cg03321784 chr17:37729644 NA 0.46 4.71 0.39 6.4e-6 Glomerular filtration rate (creatinine); TGCT cis rs12142240 0.698 rs17361915 chr1:46847321 C/T cg14993813 chr1:46806288 NSUN4 -0.59 -4.86 -0.4 3.45e-6 Menopause (age at onset); TGCT cis rs57221529 0.766 rs72703064 chr5:587825 T/C cg09021430 chr5:549028 NA -0.37 -4.98 -0.41 2.07e-6 Lung disease severity in cystic fibrosis; TGCT cis rs10504229 1.000 rs59383954 chr8:58189689 G/A cg24829409 chr8:58192753 C8orf71 -0.56 -5.3 -0.43 5.23e-7 Developmental language disorder (linguistic errors); TGCT cis rs2235642 0.893 rs2076439 chr16:1587277 C/T cg07341220 chr16:1583899 IFT140;TMEM204 -0.3 -4.72 -0.39 6.18e-6 Coronary artery disease; TGCT cis rs10504229 0.683 rs56211106 chr8:58113497 A/G cg02725872 chr8:58115012 NA -0.38 -5.05 -0.41 1.55e-6 Developmental language disorder (linguistic errors); TGCT cis rs10256972 0.591 rs6950319 chr7:1161324 A/G cg03188948 chr7:1209495 NA 0.43 5.66 0.45 9.95e-8 Longevity;Endometriosis; TGCT cis rs2549003 0.933 rs3846731 chr5:131814264 T/C cg02551604 chr5:131831745 NA -0.89 -11.77 -0.73 6.36e-22 Asthma (sex interaction); TGCT cis rs2046867 0.628 rs7356054 chr3:72912727 A/G cg25664220 chr3:72788482 NA -0.41 -5.47 -0.44 2.36e-7 Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes; TGCT cis rs9660180 1.000 rs3737628 chr1:1722932 C/T cg02915803 chr1:1606292 LOC728661;CDK11B 0.22 4.62 0.38 9.5e-6 Body mass index; TGCT cis rs11031096 0.655 rs1372806 chr11:4212308 C/T cg08557956 chr11:4115526 RRM1 -0.49 -4.56 -0.38 1.2e-5 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs6484504 0.532 rs1929019 chr11:31267030 C/T cg26647111 chr11:31128758 NA -0.35 -4.8 -0.4 4.52e-6 Red blood cell count; TGCT cis rs4808199 0.843 rs10402308 chr19:19657500 G/A cg20644253 chr19:19431407 KIAA0892;SF4 0.72 5.3 0.43 5.12e-7 Nonalcoholic fatty liver disease; TGCT cis rs12510870 0.634 rs1569204 chr4:74407090 C/T cg05868023 chr4:75230803 EREG -0.53 -4.63 -0.38 9.08e-6 Iris color (b* coordinate); TGCT cis rs617219 0.726 rs72764969 chr5:78451409 A/G cg23514016 chr5:78407564 BHMT 0.36 5.49 0.44 2.17e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs10504229 0.636 rs10958525 chr8:58051528 C/A cg11062466 chr8:58055876 NA 0.35 4.53 0.38 1.35e-5 Developmental language disorder (linguistic errors); TGCT cis rs11031096 0.568 rs10767891 chr11:4234524 A/G cg18678763 chr11:4115507 RRM1 -0.39 -5.14 -0.42 1.03e-6 Mean corpuscular volume;Mean corpuscular hemoglobin; TGCT cis rs9513593 1.000 rs1927731 chr13:99925872 G/A cg21788972 chr13:99853209 UBAC2 0.61 4.86 0.4 3.49e-6 Psoriasis; TGCT cis rs1153858 1.000 rs4625670 chr15:45652926 C/T cg14582100 chr15:45693742 SPATA5L1 0.49 5.75 0.46 6.62e-8 Homoarginine levels; TGCT cis rs10256972 0.758 rs4723649 chr7:1071905 T/C cg16145915 chr7:1198662 ZFAND2A -0.46 -5.47 -0.44 2.36e-7 Longevity;Endometriosis; TGCT cis rs11578119 0.933 rs12142689 chr1:170385558 T/C cg09767346 chr1:170501363 GORAB 0.71 5.69 0.46 8.67e-8 Male-pattern baldness; TGCT cis rs12188164 0.965 rs11739543 chr5:443676 G/A cg26850624 chr5:429559 AHRR -0.2 -4.84 -0.4 3.78e-6 Cystic fibrosis severity; TGCT cis rs17152411 1.000 rs12571196 chr10:126597749 A/C cg07906193 chr10:126599966 NA 0.4 4.55 0.38 1.24e-5 Height; TGCT cis rs981844 0.683 rs2405423 chr4:154749823 C/A cg14289246 chr4:154710475 SFRP2 -0.99 -9.12 -0.63 1.65e-15 Response to statins (LDL cholesterol change); TGCT cis rs875971 0.898 rs6977501 chr7:65693342 T/C cg11764359 chr7:65958608 NA -0.61 -5.52 -0.44 1.93e-7 Aortic root size; TGCT cis rs9952991 0.622 rs8091566 chr18:12826385 G/A cg23544223 chr18:12777786 NA 0.53 4.7 0.39 6.94e-6 Inflammatory skin disease; TGCT cis rs2243480 1.000 rs4718333 chr7:65772758 T/C cg20637647 chr7:64974828 NA -0.95 -5.3 -0.43 5.09e-7 Diabetic kidney disease; TGCT cis rs13064411 0.627 rs9825827 chr3:113182231 T/C cg18753928 chr3:113234510 CCDC52 -0.67 -5.46 -0.44 2.45e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs7714584 1.000 rs7734928 chr5:150256613 G/A cg22134413 chr5:150180641 NA 0.83 6.53 0.51 1.54e-9 Crohn's disease; TGCT cis rs1670533 1.000 rs28562028 chr4:1055115 G/A cg20887711 chr4:1340912 KIAA1530 0.71 5.7 0.46 8.33e-8 Recombination rate (females); TGCT cis rs4478858 0.735 rs6679365 chr1:31787866 A/C cg00250761 chr1:31883323 NA 0.28 5.01 0.41 1.86e-6 Alcohol dependence; TGCT cis rs7772486 0.597 rs6912351 chr6:146264071 T/C cg05347473 chr6:146136440 FBXO30 -0.64 -6.06 -0.48 1.48e-8 Lobe attachment (rater-scored or self-reported); TGCT cis rs4919694 0.711 rs113361908 chr10:104978126 T/C cg04362960 chr10:104952993 NT5C2 1.09 7.26 0.55 3.68e-11 Arsenic metabolism; TGCT cis rs17767294 0.708 rs74756732 chr6:28152547 T/A cg08851530 chr6:28072375 NA 1.47 6.82 0.52 3.64e-10 Parkinson's disease; TGCT trans rs79643899 1 rs79643899 chr5:35429449 A/C cg10378735 chr7:142558305 EPHB6 0.83 6.79 0.52 4.1e-10 Post bronchodilator FEV1 in COPD; TGCT cis rs1218582 0.772 rs4845400 chr1:154872523 C/T cg16680214 chr1:154839983 KCNN3 -0.36 -7.26 -0.55 3.81e-11 Prostate cancer; TGCT cis rs2228479 0.702 rs2074903 chr16:89811663 T/C cg06558623 chr16:89946397 TCF25 0.45 4.5 0.37 1.55e-5 Skin colour saturation; TGCT cis rs912330 0.825 rs7317938 chr13:99234361 C/T cg07423050 chr13:99094983 FARP1 -0.23 -4.46 -0.37 1.8e-5 Alzheimer's disease; TGCT cis rs4566357 0.615 rs4675139 chr2:227908527 G/A cg11843606 chr2:227700838 RHBDD1 -0.54 -5.04 -0.41 1.59e-6 Coronary artery disease; TGCT cis rs7647973 0.626 rs2329021 chr3:49679072 G/A cg05785598 chr3:49045655 WDR6 0.42 5.24 0.43 6.67e-7 Menarche (age at onset); TGCT cis rs3771570 1.000 rs56363214 chr2:242227157 A/G cg21155796 chr2:242212141 HDLBP 0.98 6.68 0.51 7.29e-10 Prostate cancer; TGCT cis rs931127 0.512 rs58950470 chr11:65383755 G/T cg27068330 chr11:65405492 SIPA1 0.59 5.17 0.42 9.24e-7 Systemic lupus erythematosus; TGCT cis rs477895 0.653 rs12797120 chr11:63906819 C/T cg19465662 chr11:63993652 NUDT22;TRPT1 0.78 6.27 0.49 5.58e-9 Mean platelet volume; TGCT cis rs6684514 0.922 rs12022657 chr1:156314147 A/G cg20302342 chr1:156215951 PAQR6 0.34 4.52 0.38 1.45e-5 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs514406 0.929 rs557920 chr1:53338757 C/A cg08859206 chr1:53392774 SCP2 -0.41 -6.33 -0.49 4.13e-9 Monocyte count; TGCT trans rs8073060 0.544 rs225249 chr17:33942540 T/C cg19694781 chr19:47549865 TMEM160 -0.61 -13.7 -0.78 1.39e-26 Immature fraction of reticulocytes;Platelet count;Platelet distribution width; TGCT cis rs10501293 0.643 rs10837996 chr11:43028439 A/G cg03447554 chr11:43094025 NA 0.44 6.28 0.49 5.14e-9 Cognitive performance; TGCT cis rs2073300 1.000 rs12626013 chr20:23442215 G/A cg09953122 chr20:23471693 CST8 -0.64 -4.56 -0.38 1.19e-5 Peripheral arterial disease (traffic-related air pollution interaction); TGCT cis rs6748734 1.000 rs4344931 chr2:241818527 A/C cg04034577 chr2:241836375 C2orf54 -0.39 -6.27 -0.49 5.49e-9 Urinary metabolites; TGCT cis rs9914544 0.689 rs11078421 chr17:18804385 A/G cg26378065 chr17:18585709 ZNF286B 0.51 4.54 0.38 1.33e-5 Educational attainment (years of education); TGCT cis rs6570726 0.846 rs426874 chr6:145880630 A/C cg23711669 chr6:146136114 FBXO30 0.82 8.6 0.61 2.96e-14 Lobe attachment (rater-scored or self-reported); TGCT trans rs1005277 0.579 rs2505257 chr10:38372664 A/G cg27523141 chr10:43048294 ZNF37B 0.74 8.49 0.61 5.31e-14 Extrinsic epigenetic age acceleration; TGCT trans rs7618501 0.633 rs4688758 chr3:50028385 G/A cg21665057 chr3:196295764 WDR53;FBXO45 0.86 9.38 0.64 3.95e-16 Intelligence (multi-trait analysis); TGCT cis rs4242434 0.819 rs2291230 chr8:22463697 C/G cg03733263 chr8:22462867 KIAA1967 1.08 17.46 0.84 3.22e-35 Exploratory eye movement dysfunction in schizophrenia (cognitive search score); TGCT cis rs1005277 0.579 rs2474587 chr10:38420666 C/T cg25427524 chr10:38739819 LOC399744 -0.39 -8.03 -0.58 6.56e-13 Extrinsic epigenetic age acceleration; TGCT cis rs1997103 1.000 rs10249105 chr7:55412405 A/G cg17469321 chr7:55412551 NA -0.58 -6.22 -0.49 6.9e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs9303542 0.559 rs12603976 chr17:46617163 C/A cg25032089 chr17:46643351 HOXB3 0.56 5.34 0.43 4.22e-7 Ovarian cancer;Epithelial ovarian cancer; TGCT cis rs6893807 1.000 rs6893807 chr5:87965021 C/T cg24804195 chr5:87968844 LOC645323 -0.73 -5.57 -0.45 1.52e-7 Body mass index; TGCT cis rs11190604 0.767 rs10748794 chr10:102175918 G/T cg23241863 chr10:102295624 HIF1AN -0.64 -4.86 -0.4 3.54e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs8077889 0.871 rs16940243 chr17:41900003 C/G cg26893861 chr17:41843967 DUSP3 1.09 13.08 0.76 4.26e-25 Triglycerides; TGCT cis rs1008375 0.966 rs3775923 chr4:17585625 T/C cg10189774 chr4:17578691 LAP3 0.61 5.28 0.43 5.6e-7 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs6840360 0.573 rs4696250 chr4:152266321 T/C cg17479576 chr4:152424074 FAM160A1 -0.43 -4.48 -0.37 1.68e-5 Intelligence (multi-trait analysis); TGCT cis rs67478160 0.619 rs11160761 chr14:104254856 A/T cg26031613 chr14:104095156 KLC1 -0.64 -6.58 -0.51 1.2e-9 Schizophrenia; TGCT cis rs7731657 0.537 rs971700 chr5:130361575 T/G cg08523029 chr5:130500466 HINT1 -0.61 -5.08 -0.42 1.34e-6 Fasting plasma glucose; TGCT trans rs1973993 0.967 rs10489741 chr1:96942406 G/A cg10631902 chr5:14652156 NA 0.31 7.01 0.53 1.38e-10 Weight; TGCT cis rs16957091 0.647 rs7170376 chr15:43327104 G/C cg17935677 chr15:44119062 WDR76 0.52 4.71 0.39 6.44e-6 MGMT methylation in smokers; TGCT cis rs11098499 0.863 rs2170276 chr4:120485824 A/C cg09307838 chr4:120376055 NA 0.72 6.9 0.53 2.41e-10 Corneal astigmatism; TGCT cis rs8014204 0.836 rs12888998 chr14:75292662 G/T cg06637938 chr14:75390232 RPS6KL1 0.7 6.74 0.52 5.37e-10 Caffeine consumption; TGCT cis rs7209700 0.963 rs1000232 chr17:45356561 T/C cg21624342 chr17:45890973 OSBPL7 0.17 4.76 0.39 5.39e-6 IgG glycosylation; TGCT cis rs28595532 0.920 rs56364904 chr4:119742504 T/C cg21605333 chr4:119757512 SEC24D 1.56 8.33 0.6 1.25e-13 Cannabis dependence symptom count; TGCT cis rs6684514 1.000 rs66965793 chr1:156285814 G/A cg16558208 chr1:156270281 VHLL 0.48 9.6 0.65 1.19e-16 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs394563 0.591 rs237016 chr6:149744859 T/C cg16235748 chr6:149772707 ZC3H12D -0.41 -4.62 -0.38 9.34e-6 Dupuytren's disease; TGCT cis rs1018836 0.631 rs9987164 chr8:91470910 T/G cg16814680 chr8:91681699 NA -0.77 -7.57 -0.56 7.42e-12 Ejection fraction in Tripanosoma cruzi seropositivity; TGCT cis rs2739330 0.828 rs2154593 chr22:24252085 A/G cg00024416 chr22:24240387 NA -0.26 -4.93 -0.4 2.61e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs7937612 1.000 rs723937 chr11:120312746 G/A cg24566217 chr11:120254723 ARHGEF12 -0.31 -5.19 -0.42 8.16e-7 Intraocular pressure; TGCT cis rs9393777 0.513 rs9368448 chr6:26649355 T/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.53 -4.88 -0.4 3.19e-6 Intelligence (multi-trait analysis); TGCT cis rs6089829 0.926 rs1060491 chr20:61665817 C/A cg03213289 chr20:61660250 NA -0.63 -8.45 -0.6 6.67e-14 Prostate cancer (SNP x SNP interaction); TGCT cis rs9303401 0.659 rs34913878 chr17:56897094 A/G cg25039879 chr17:56429692 SUPT4H1 0.51 4.5 0.37 1.54e-5 Cognitive test performance; TGCT cis rs7179456 0.547 rs6494035 chr15:59015888 C/G cg05156742 chr15:59063176 FAM63B 0.53 5.13 0.42 1.09e-6 Asperger disorder; TGCT cis rs950169 0.509 rs71395455 chr15:85153804 A/G cg17173187 chr15:85201210 NMB 0.53 5.88 0.47 3.53e-8 Schizophrenia; TGCT cis rs12893668 0.667 rs11844466 chr14:104066422 G/A cg26031613 chr14:104095156 KLC1 -0.55 -4.64 -0.38 8.81e-6 Reticulocyte count; TGCT cis rs7582180 0.629 rs11682557 chr2:100948008 C/A cg14675211 chr2:100938903 LONRF2 0.51 4.84 0.4 3.83e-6 Intelligence (multi-trait analysis); TGCT cis rs7586879 0.828 rs13012304 chr2:25122246 C/T cg01884057 chr2:25150051 NA 0.27 4.81 0.4 4.36e-6 Body mass index; TGCT trans rs7698623 0.850 rs4693883 chr4:88770174 A/G cg01186725 chr1:53905612 FLJ40434 -0.48 -6.63 -0.51 9.21e-10 Cardiovascular disease risk factors; TGCT cis rs832540 0.603 rs6870175 chr5:56093371 A/G cg24531977 chr5:56204891 C5orf35 -0.54 -5.34 -0.43 4.33e-7 Coronary artery disease; TGCT cis rs12497850 0.931 rs6446205 chr3:49035211 C/T cg05785598 chr3:49045655 WDR6 0.37 4.89 0.4 3.04e-6 Parkinson's disease; TGCT cis rs1942 1.000 rs1942 chr15:41774423 A/G cg18705301 chr15:41695430 NDUFAF1 -0.47 -6.67 -0.51 7.59e-10 Eosinophil percentage of granulocytes; TGCT cis rs3806843 0.583 rs408652 chr5:140330013 T/G cg09824255 chr5:140014002 CD14 0.25 4.62 0.38 9.6e-6 Depressive symptoms (multi-trait analysis); TGCT cis rs1153858 1.000 rs11070456 chr15:45686835 G/A cg26924012 chr15:45694286 SPATA5L1 1.09 15.16 0.81 5.15e-30 Homoarginine levels; TGCT cis rs7208859 0.524 rs73988172 chr17:29086332 A/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs1790761 0.501 rs4930210 chr11:67404726 G/T cg24690094 chr11:67383802 NA -0.33 -5.07 -0.41 1.44e-6 Mean corpuscular volume; TGCT cis rs6589563 0.609 rs12285095 chr11:116658031 T/G cg01124546 chr11:117515332 DSCAML1 -0.47 -4.56 -0.38 1.2e-5 Eosinophil counts; TGCT cis rs3785574 0.962 rs2584614 chr17:61929445 C/T cg11494091 chr17:61959527 GH2 0.43 7.47 0.56 1.23e-11 Height; TGCT cis rs13191362 0.810 rs34714603 chr6:163008078 C/T cg06582575 chr6:163149167 PACRG;PARK2 0.57 4.94 0.41 2.45e-6 Body mass index;BMI in non-smokers;Body mass index (joint analysis main effects and physical activity interaction);BMI (adjusted for smoking behaviour);Body mass index in physically active individuals;Body mass index (joint analysis main effects and smoking interaction); TGCT cis rs7698623 0.717 rs1982624 chr4:88790847 A/G cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs7223966 1.000 rs8076717 chr17:61850301 C/T cg23090583 chr17:61904693 PSMC5;FTSJ3 -0.58 -4.62 -0.38 9.63e-6 Hip circumference adjusted for BMI;Body mass index; TGCT cis rs2288884 1.000 rs80278704 chr19:52549183 G/A cg15405931 chr19:52693188 PPP2R1A -0.69 -4.5 -0.37 1.56e-5 Bronchodilator response in asthma (inhaled corticosteroid treatment interaction); TGCT cis rs68170813 0.522 rs12531187 chr7:106963650 C/G cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs1372520 0.684 rs2737030 chr4:90710099 C/T cg01966878 chr4:90757139 SNCA -0.31 -5.01 -0.41 1.83e-6 Neuroticism; TGCT cis rs17125944 0.686 rs7147258 chr14:53337664 G/T cg00686598 chr14:53173677 PSMC6 -0.86 -4.55 -0.38 1.29e-5 Alzheimer's disease (late onset); TGCT cis rs2243480 1.000 rs34529418 chr7:65403209 A/G cg07424592 chr7:64974309 NA 1.34 8.08 0.59 4.95e-13 Diabetic kidney disease; TGCT cis rs7226408 0.948 rs17567550 chr18:34398678 G/C cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs7246657 0.943 rs13345116 chr19:37847098 A/T cg03233940 chr19:37894644 NA -0.34 -4.49 -0.37 1.59e-5 Coronary artery calcification; TGCT cis rs9911578 0.967 rs302843 chr17:56727986 C/T cg05425664 chr17:57184151 TRIM37 -0.64 -6.48 -0.5 1.99e-9 Intelligence (multi-trait analysis); TGCT cis rs6671200 0.831 rs11582082 chr1:95594697 A/G cg03123541 chr1:95699097 RWDD3 0.73 4.85 0.4 3.56e-6 Stearic acid (18:0) levels; TGCT cis rs11690935 0.959 rs35391289 chr2:172634983 A/C cg13550731 chr2:172543902 DYNC1I2 -1.19 -12.78 -0.75 2.24e-24 Schizophrenia; TGCT cis rs6570726 0.935 rs374000 chr6:145855290 C/T cg23711669 chr6:146136114 FBXO30 0.71 7.03 0.53 1.25e-10 Lobe attachment (rater-scored or self-reported); TGCT cis rs9372253 0.967 rs1055301 chr6:110713042 A/G cg13266496 chr6:110720918 DDO -0.45 -5.5 -0.44 2.11e-7 Platelet distribution width; TGCT cis rs67311347 1.000 rs9842564 chr3:40405810 A/G cg13683864 chr3:40499215 RPL14 1.07 10.53 0.69 6.45e-19 Renal cell carcinoma; TGCT cis rs319204 0.885 rs577197 chr5:146287207 T/C cg25021259 chr5:146258546 PPP2R2B 0.35 4.49 0.37 1.64e-5 Schizophrenia; TGCT cis rs739496 0.542 rs7306529 chr12:111780644 A/G cg10833066 chr12:111807467 FAM109A 0.42 7.72 0.57 3.29e-12 Platelet count; TGCT cis rs732765 0.602 rs2359192 chr14:75410523 A/C cg06637938 chr14:75390232 RPS6KL1 -0.64 -5.82 -0.46 4.68e-8 Non-small cell lung cancer; TGCT cis rs6951245 1.000 rs76804143 chr7:1082021 C/T cg18402987 chr7:1209562 NA 0.7 5.67 0.45 9.66e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs9611565 0.694 rs5758324 chr22:41787950 G/T cg17554472 chr22:41940697 POLR3H -0.45 -4.86 -0.4 3.44e-6 Vitiligo; TGCT cis rs7698623 0.850 rs4693894 chr4:88797798 C/T cg27387453 chr4:88533842 DSPP -0.61 -4.6 -0.38 1.03e-5 Cardiovascular disease risk factors; TGCT cis rs875971 0.862 rs2088653 chr7:65808608 G/A cg11764359 chr7:65958608 NA -0.55 -4.99 -0.41 1.98e-6 Aortic root size; TGCT cis rs2295359 0.643 rs1569923 chr1:67665210 A/G cg12940439 chr1:67600707 NA 0.44 4.68 0.39 7.53e-6 Psoriasis; TGCT cis rs2243480 1.000 rs3885839 chr7:65290403 G/T cg18252515 chr7:66147081 NA -1.1 -6.4 -0.5 2.85e-9 Diabetic kidney disease; TGCT cis rs7552404 1.000 rs7513559 chr1:76173744 A/G cg03433033 chr1:76189801 ACADM 0.83 9.91 0.66 2.13e-17 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs28374715 0.662 rs111522288 chr15:41480169 C/T cg18705301 chr15:41695430 NDUFAF1 -0.81 -11.6 -0.72 1.65e-21 Ulcerative colitis; TGCT cis rs10504229 0.773 rs60466370 chr8:58171248 A/C cg22535103 chr8:58192502 C8orf71 -0.35 -4.65 -0.39 8.4e-6 Developmental language disorder (linguistic errors); TGCT cis rs2115630 1.000 rs56074163 chr15:85351332 C/T cg11189052 chr15:85197271 WDR73 -0.61 -5.89 -0.47 3.35e-8 P wave terminal force; TGCT cis rs9926296 0.712 rs258332 chr16:89727683 G/A cg27121462 chr16:89883253 FANCA -0.54 -4.93 -0.4 2.58e-6 Vitiligo; TGCT cis rs10992471 0.651 rs7043984 chr9:95529408 C/T cg13798575 chr9:95087839 CENPP;NOL8 -0.59 -5.59 -0.45 1.39e-7 Visceral adipose tissue/subcutaneous adipose tissue ratio; TGCT cis rs12134245 0.776 rs12124682 chr1:91995542 A/G cg02896835 chr1:92012615 NA -0.27 -4.59 -0.38 1.08e-5 Breast cancer; TGCT cis rs988712 0.622 rs7103411 chr11:27700125 C/T cg10635145 chr11:27742435 BDNF 0.42 5.96 0.47 2.44e-8 Obesity; TGCT cis rs9916302 0.904 rs8065879 chr17:37515978 G/A cg15445000 chr17:37608096 MED1 -0.33 -4.74 -0.39 5.87e-6 Glomerular filtration rate (creatinine); TGCT cis rs1218582 0.772 rs6669791 chr1:154845484 G/T cg24250549 chr1:154909240 PMVK 0.62 6.16 0.48 9.3e-9 Prostate cancer; TGCT cis rs459571 0.959 rs460888 chr9:136913123 C/G cg14405625 chr9:136855902 VAV2 -0.32 -4.72 -0.39 6.15e-6 Platelet distribution width; TGCT cis rs2303745 0.589 rs6512182 chr19:17399476 G/T cg04248312 chr19:17393744 ANKLE1 -0.34 -5.57 -0.45 1.54e-7 Systemic lupus erythematosus; TGCT cis rs4455778 0.659 rs7784468 chr7:49020696 A/C cg26309511 chr7:48887640 NA -0.43 -5.07 -0.41 1.4e-6 Lung cancer in never smokers; TGCT cis rs904251 0.523 rs2776870 chr6:37481364 C/A cg01843034 chr6:37503916 NA -0.56 -7.56 -0.56 7.84e-12 Cognitive performance; TGCT cis rs10114408 0.959 rs10821248 chr9:96645884 G/A cg13679303 chr9:96623674 NA -0.36 -4.68 -0.39 7.28e-6 Colorectal cancer (SNP x SNP interaction); TGCT cis rs12477438 0.765 rs2309454 chr2:99595418 G/A cg15544633 chr2:99771531 LIPT1;TSGA10 -0.76 -7.6 -0.56 6.47e-12 Chronic sinus infection; TGCT cis rs736408 0.609 rs2230535 chr3:52800284 T/C cg10802521 chr3:52805072 NEK4 -0.74 -9.02 -0.63 2.87e-15 Bipolar disorder; TGCT cis rs7666738 0.791 rs62318641 chr4:98816964 T/C cg17366294 chr4:99064904 C4orf37 0.7 7.45 0.56 1.42e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs933688 0.941 rs2887007 chr5:90740531 A/T cg26981201 chr5:90679533 LOC100129716;ARRDC3 1.02 9.32 0.64 5.66e-16 Smoking behavior; TGCT cis rs2032447 0.869 rs199752 chr6:26012875 C/T cg03517284 chr6:25882590 NA -0.63 -5.65 -0.45 1.04e-7 Intelligence (multi-trait analysis); TGCT cis rs7949030 0.626 rs61296092 chr11:62320838 T/C cg13298116 chr11:62369859 EML3;MTA2 0.65 9.51 0.65 1.98e-16 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7666738 0.962 rs1527515 chr4:99025733 C/A cg17366294 chr4:99064904 C4orf37 0.76 7.12 0.54 7.6e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs9309473 0.687 rs6747145 chr2:73609177 C/T cg20560298 chr2:73613845 ALMS1 -0.45 -5.01 -0.41 1.82e-6 Metabolite levels; TGCT cis rs172166 0.694 rs203884 chr6:28077374 G/T cg10876282 chr6:28092338 ZSCAN16 0.49 4.64 0.38 8.6e-6 Cardiac Troponin-T levels; TGCT cis rs12142240 0.698 rs77185326 chr1:46818417 T/C cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT trans rs9929218 0.507 rs62057805 chr16:68742390 G/C cg04657470 chr2:198365150 HSPE1;HSPD1 0.62 8.1 0.59 4.5e-13 Colorectal cancer; TGCT cis rs2050392 0.517 rs602966 chr10:30755853 C/T cg18806716 chr10:30721971 MAP3K8 -0.58 -6.77 -0.52 4.51e-10 Inflammatory bowel disease; TGCT cis rs11809207 0.857 rs11247866 chr1:26517794 A/G cg03844060 chr1:26490628 NA 0.25 4.62 0.38 9.44e-6 Height; TGCT cis rs7213347 0.555 rs2760751 chr17:2028106 A/G cg13315690 chr17:1944831 OVCA2;DPH1 -0.39 -4.83 -0.4 3.97e-6 Total body bone mineral density; TGCT cis rs9814567 0.896 rs7653807 chr3:134345724 T/C cg06109529 chr3:134205091 CEP63;ANAPC13 -0.82 -7.38 -0.55 2e-11 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs881375 0.692 rs2072438 chr9:123651301 T/C cg09586646 chr9:123605570 PSMD5;LOC253039 0.39 4.48 0.37 1.69e-5 Rheumatoid arthritis; TGCT cis rs4911259 0.552 rs11697394 chr20:31460076 G/A cg13636640 chr20:31349939 DNMT3B -0.89 -9.82 -0.66 3.4e-17 Inflammatory bowel disease; TGCT cis rs2019137 0.967 rs895412 chr2:113973964 T/C cg27425262 chr2:113953981 PSD4;LOC440839 -0.52 -7.84 -0.58 1.73e-12 Lymphocyte counts; TGCT cis rs7811142 1.000 rs67239991 chr7:100046504 A/G cg13153964 chr7:100026424 MEPCE;ZCWPW1 1.01 8.39 0.6 9.03e-14 Platelet count; TGCT cis rs9790314 0.812 rs7631479 chr3:161139566 C/T cg03342759 chr3:160939853 NMD3 -0.45 -4.49 -0.37 1.58e-5 Morning vs. evening chronotype; TGCT cis rs506338 0.517 rs516117 chr11:64433444 T/C cg19395706 chr11:64412079 NRXN2 0.49 5.96 0.47 2.41e-8 Body mass index;Urate levels; TGCT cis rs1971762 0.527 rs1247956 chr12:53963814 G/T cg16917193 chr12:54089295 NA -1.04 -11.02 -0.7 4.2e-20 Height; TGCT cis rs7824557 0.602 rs7839053 chr8:11207431 C/T cg21775007 chr8:11205619 TDH 0.73 7.03 0.53 1.23e-10 Retinal vascular caliber; TGCT cis rs8017423 0.935 rs7144070 chr14:90753047 T/C cg04374321 chr14:90722782 PSMC1 0.76 7.46 0.56 1.33e-11 Mortality in heart failure; TGCT cis rs7772486 0.875 rs10457794 chr6:146415608 A/G cg05347473 chr6:146136440 FBXO30 0.56 5.22 0.42 7.31e-7 Lobe attachment (rater-scored or self-reported); TGCT cis rs6088580 0.634 rs6120644 chr20:33023810 G/A cg06115741 chr20:33292138 TP53INP2 0.55 4.82 0.4 4.15e-6 Glomerular filtration rate (creatinine); TGCT cis rs1729951 0.546 rs835634 chr3:136676303 C/T cg12473912 chr3:136751656 NA 0.39 6.18 0.49 8.36e-9 Neuroticism; TGCT cis rs1997103 0.834 rs10274457 chr7:55390199 G/A cg17469321 chr7:55412551 NA 0.64 6.55 0.51 1.4e-9 QRS interval (sulfonylurea treatment interaction); TGCT cis rs11711311 1.000 rs10934243 chr3:113430239 T/A cg06805542 chr3:113465803 ATP6V1A;NAA50 -0.73 -6.83 -0.52 3.45e-10 IgG glycosylation; TGCT cis rs3749237 0.964 rs1799843 chr3:49849723 G/A cg07636037 chr3:49044803 WDR6 0.61 5.41 0.44 3.08e-7 Resting heart rate; TGCT cis rs2075371 0.835 rs1646724 chr7:134001875 T/G cg11752832 chr7:134001865 SLC35B4 0.82 7.74 0.57 3.06e-12 Mean platelet volume; TGCT cis rs4499344 0.586 rs2903753 chr19:33053116 C/T cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.73 -6.21 -0.49 7.33e-9 Mean platelet volume; TGCT cis rs2760061 0.545 rs1745423 chr1:228224153 G/T cg02753203 chr1:228287806 NA -0.36 -7.64 -0.57 5.17e-12 Diastolic blood pressure; TGCT cis rs1541995 0.931 rs6496136 chr15:96319875 A/T cg00882281 chr15:96346592 NA 0.28 4.56 0.38 1.19e-5 Photic sneeze reflex; TGCT cis rs6964587 0.692 rs2158138 chr7:91700879 A/G cg17063962 chr7:91808500 NA 0.74 6.96 0.53 1.75e-10 Breast cancer; TGCT cis rs910187 0.678 rs6124965 chr20:45812957 T/G cg27589058 chr20:45804311 EYA2 -0.35 -7.6 -0.56 6.23e-12 Migraine; TGCT cis rs10186029 0.680 rs10179425 chr2:213978441 T/C cg08319019 chr2:214017104 IKZF2 0.65 5.95 0.47 2.49e-8 Systemic sclerosis; TGCT cis rs68170813 0.559 rs75203426 chr7:107017589 G/C cg02696742 chr7:106810147 HBP1 -0.7 -5.7 -0.46 8.16e-8 Coronary artery disease; TGCT cis rs7681440 0.647 rs1442133 chr4:90819195 C/T cg10208370 chr4:90758469 SNCA -0.57 -5.4 -0.44 3.19e-7 Dementia with Lewy bodies; TGCT cis rs7267979 1.000 rs2027003 chr20:25350498 A/G cg16686733 chr20:25566563 NINL -0.59 -5.99 -0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs514406 0.708 rs480299 chr1:53320274 G/T cg24675658 chr1:53192096 ZYG11B -0.82 -10.02 -0.67 1.1e-17 Monocyte count; TGCT cis rs2832191 0.703 rs2853827 chr21:30443596 T/C cg24692254 chr21:30365293 RNF160 0.98 11.39 0.72 5.22e-21 Dental caries; TGCT cis rs6840360 1.000 rs6823421 chr4:152604719 T/C cg17479576 chr4:152424074 FAM160A1 -0.46 -4.8 -0.4 4.53e-6 Intelligence (multi-trait analysis); TGCT cis rs9929218 0.954 rs34530130 chr16:68827620 C/T cg03880890 chr16:69439245 NA -0.22 -4.48 -0.37 1.68e-5 Colorectal cancer; TGCT cis rs6785206 0.527 rs4040753 chr3:128656781 C/T cg25356066 chr3:128598488 ACAD9 -0.71 -4.45 -0.37 1.85e-5 Lymphocyte percentage of white cells; TGCT cis rs2739330 0.760 rs5760095 chr22:24247293 A/G cg24846343 chr22:24311635 DDTL 0.22 5.71 0.46 7.82e-8 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs8056742 0.571 rs9922192 chr16:85003815 A/T cg00229868 chr16:85520891 NA 0.35 4.51 0.38 1.47e-5 Amyotrophic lateral sclerosis; TGCT cis rs9527 0.590 rs11191547 chr10:104843148 C/T cg04362960 chr10:104952993 NT5C2 0.69 5.75 0.46 6.42e-8 Arsenic metabolism; TGCT cis rs1865760 0.602 rs2157050 chr6:26020431 C/T cg16482183 chr6:26056742 HIST1H1C 0.56 4.78 0.39 4.96e-6 Height; TGCT cis rs2013441 1.000 rs2120282 chr17:20209474 C/T cg18979559 chr17:20280153 CCDC144C -0.49 -4.99 -0.41 1.97e-6 Obesity-related traits; TGCT cis rs2153535 0.580 rs9405390 chr6:8466209 T/G cg07606381 chr6:8435919 SLC35B3 0.54 5.09 0.42 1.32e-6 Motion sickness; TGCT cis rs12681287 0.604 rs41469550 chr8:87406544 G/T cg27223183 chr8:87520930 FAM82B 0.87 6.39 0.5 3e-9 Caudate activity during reward; TGCT cis rs224278 0.782 rs224292 chr10:64588424 G/A cg22903908 chr10:64578919 EGR2 0.38 4.72 0.39 6.14e-6 Ewing sarcoma; TGCT cis rs9902453 0.817 rs2321333 chr17:28140857 A/T cg26525008 chr17:28256777 EFCAB5;SSH2 0.83 7.95 0.58 9.99e-13 Coffee consumption (cups per day); TGCT cis rs8038465 1.000 rs8032531 chr15:73977271 A/G cg15420318 chr15:73925796 NPTN 0.71 6.56 0.51 1.3e-9 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs3845702 0.668 rs3856415 chr2:180807367 G/A cg01881094 chr2:180872142 CWC22 -1.05 -6.78 -0.52 4.27e-10 Schizophrenia; TGCT cis rs2663905 0.611 rs2663920 chr15:81396404 A/G cg09888468 chr15:81410853 NA -0.63 -5.4 -0.44 3.25e-7 QT interval (drug interaction); TGCT cis rs2013441 0.804 rs1811453 chr17:20232193 A/C cg18979559 chr17:20280153 CCDC144C -0.45 -4.67 -0.39 7.61e-6 Obesity-related traits; TGCT cis rs28386778 0.863 rs6504178 chr17:61812733 A/G cg26338869 chr17:61819248 STRADA 0.55 5.1 0.42 1.22e-6 Prudent dietary pattern; TGCT cis rs10779751 1.000 rs7549109 chr1:11278813 C/G cg08854313 chr1:11322531 MTOR -0.92 -10.06 -0.67 9.08e-18 Body mass index; TGCT cis rs9549260 0.755 rs55920113 chr13:41222112 C/T cg21288729 chr13:41239152 FOXO1 0.99 10.42 0.68 1.22e-18 Red blood cell count; TGCT cis rs11785400 1.000 rs3735994 chr8:143742683 C/T cg10596483 chr8:143751796 JRK 0.56 6.05 0.48 1.61e-8 Schizophrenia; TGCT cis rs9910055 0.762 rs2240226 chr17:42266218 C/T cg10896456 chr17:42255109 ASB16;C17orf65 0.25 4.48 0.37 1.65e-5 Total body bone mineral density; TGCT cis rs2050392 0.624 rs303436 chr10:30731893 G/T cg13289132 chr10:30722225 MAP3K8 -0.48 -6.07 -0.48 1.41e-8 Inflammatory bowel disease; TGCT cis rs9653442 0.510 rs13415583 chr2:100764087 T/G cg07810366 chr2:100720526 AFF3 -0.36 -5.31 -0.43 4.89e-7 Type 1 diabetes;Rheumatoid arthritis;Intelligence (multi-trait analysis); TGCT cis rs3806843 0.520 rs246051 chr5:140326464 G/A cg09824255 chr5:140014002 CD14 0.25 4.58 0.38 1.14e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs6545883 0.929 rs2592352 chr2:61665336 C/T cg15711740 chr2:61764176 XPO1 -0.56 -5.07 -0.41 1.42e-6 Tuberculosis; TGCT cis rs79349575 0.783 rs4793996 chr17:47019597 T/C cg00947319 chr17:47005597 UBE2Z -0.19 -4.52 -0.38 1.44e-5 Type 2 diabetes; TGCT cis rs28386778 0.897 rs4638645 chr17:61828349 T/C cg01411255 chr17:61851458 DDX42;CCDC47 0.76 7.36 0.55 2.25e-11 Prudent dietary pattern; TGCT cis rs1030877 1.000 rs2576743 chr2:105901337 C/T cg02079111 chr2:105885981 TGFBRAP1 0.19 5.69 0.45 8.77e-8 Obesity-related traits; TGCT trans rs1864729 1.000 rs2853318 chr8:98283509 A/T cg08679828 chr8:102218111 ZNF706 -1.08 -7.52 -0.56 9.47e-12 Estradiol plasma levels (breast cancer); TGCT cis rs10504229 0.906 rs113857287 chr8:58191683 T/C cg22535103 chr8:58192502 C8orf71 -0.41 -5.19 -0.42 8.4e-7 Developmental language disorder (linguistic errors); TGCT trans rs1005277 0.579 rs2474574 chr10:38387295 C/T cg17830980 chr10:43048298 ZNF37B -0.86 -11.18 -0.71 1.68e-20 Extrinsic epigenetic age acceleration; TGCT cis rs6570726 0.791 rs4896820 chr6:145894957 T/C cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs4665809 0.590 rs1056389 chr2:26502875 T/C cg25036284 chr2:26402008 FAM59B 0.65 5.19 0.42 8.36e-7 Gut microbiome composition (summer); TGCT cis rs9972944 0.729 rs10083872 chr17:63773474 A/G cg07283582 chr17:63770753 CCDC46 0.26 5.05 0.41 1.53e-6 Total body bone mineral density; TGCT cis rs11673344 0.504 rs8099987 chr19:37623472 T/C cg08039142 chr19:36980659 ZNF566 0.51 4.68 0.39 7.31e-6 Obesity-related traits; TGCT cis rs36051895 0.664 rs10117459 chr9:5094034 G/A cg02405213 chr9:5042618 JAK2 -0.7 -9.05 -0.63 2.49e-15 Pediatric autoimmune diseases; TGCT cis rs875971 0.505 rs2462573 chr7:65507392 C/T cg00343986 chr7:65444356 GUSB -0.25 -5.81 -0.46 4.89e-8 Aortic root size; TGCT cis rs7811142 1.000 rs6953107 chr7:100095664 C/T cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.08 9.11 0.63 1.81e-15 Platelet count; TGCT cis rs3849570 0.695 rs1851930 chr3:81895318 T/G cg07356753 chr3:81810745 GBE1 -0.64 -5.59 -0.45 1.35e-7 Waist circumference;Body mass index; TGCT cis rs4783244 0.897 rs4783241 chr16:82650384 G/C cg09415485 chr16:82663111 CDH13 -0.26 -4.98 -0.41 2.07e-6 Adiponectin levels; TGCT cis rs6001982 0.510 rs55844816 chr22:40803112 C/T cg07138101 chr22:40742427 ADSL 0.71 4.72 0.39 6.31e-6 Breast cancer; TGCT cis rs1538970 0.962 rs7532762 chr1:45864695 C/A cg05343316 chr1:45956843 TESK2 0.7 5.35 0.43 4.04e-7 Platelet count; TGCT cis rs1372520 0.935 rs2245801 chr4:90757840 T/C cg15133208 chr4:90757351 SNCA -0.53 -5.88 -0.47 3.53e-8 Neuroticism; TGCT cis rs7666738 0.830 rs1426668 chr4:98945585 T/A cg17366294 chr4:99064904 C4orf37 0.73 7.47 0.56 1.24e-11 Colonoscopy-negative controls vs population controls; TGCT cis rs17197710 0.608 rs4647736 chr11:47253137 C/T cg13308137 chr11:47528955 CUGBP1 0.4 5.18 0.42 8.8e-7 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs7727544 0.684 rs274567 chr5:131714409 C/T cg24060327 chr5:131705240 SLC22A5 0.57 6.4 0.5 2.91e-9 Blood metabolite levels; TGCT cis rs748404 0.660 rs509306 chr15:43715171 A/G cg02155558 chr15:43621948 ADAL;LCMT2 0.47 4.75 0.39 5.51e-6 Lung cancer; TGCT cis rs2806561 0.765 rs1738470 chr1:23511911 G/A cg12483005 chr1:23474871 LUZP1 0.38 4.73 0.39 5.93e-6 Height; TGCT cis rs13188771 0.578 rs17137390 chr5:100918526 C/T cg10455971 chr5:101119566 NA 0.48 4.77 0.39 5.16e-6 Conduct disorder (maternal expressed emotions interaction); TGCT cis rs7264396 0.635 rs6060675 chr20:34493614 C/T cg04508476 chr20:34239394 CPNE1;RBM12 -0.29 -5.06 -0.41 1.47e-6 Total cholesterol levels; TGCT cis rs7914558 1.000 rs7077291 chr10:104945751 C/T cg04362960 chr10:104952993 NT5C2 0.61 5.47 0.44 2.42e-7 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs7523273 0.564 rs1977265 chr1:207880683 G/T cg22525895 chr1:207977042 MIR29B2 -0.29 -4.51 -0.38 1.48e-5 Schizophrenia; TGCT cis rs73058052 0.935 rs3745474 chr19:50086806 C/T cg09250473 chr19:50168907 IRF3;BCL2L12 0.85 6.59 0.51 1.12e-9 Fibrinogen levels; TGCT cis rs7267979 0.789 rs4815400 chr20:25292560 T/C cg03522245 chr20:25566470 NINL -0.55 -5.55 -0.45 1.68e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6912958 0.559 rs451465 chr6:88043372 C/T cg12350822 chr6:88032061 C6orf162;GJB7 -0.45 -5.9 -0.47 3.19e-8 Monocyte percentage of white cells; TGCT cis rs79349575 0.783 rs832410 chr17:46972865 C/T cg26022315 chr17:47021804 SNF8 0.47 4.55 0.38 1.28e-5 Type 2 diabetes; TGCT cis rs1008375 1.000 rs10805358 chr4:17652450 A/C cg18681998 chr4:17616180 MED28 0.99 11.78 0.73 5.86e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs10504229 0.728 rs72650861 chr8:58153273 T/C cg22535103 chr8:58192502 C8orf71 -0.42 -4.79 -0.4 4.7e-6 Developmental language disorder (linguistic errors); TGCT cis rs2153535 0.580 rs4960422 chr6:8459309 T/C cg23788917 chr6:8435910 SLC35B3 0.63 5.72 0.46 7.7e-8 Motion sickness; TGCT cis rs3820928 0.839 rs35068645 chr2:227844265 T/C cg11843606 chr2:227700838 RHBDD1 -0.52 -4.59 -0.38 1.05e-5 Pulmonary function; TGCT cis rs7666738 0.791 rs4440223 chr4:99044796 G/A cg17366294 chr4:99064904 C4orf37 0.74 7.57 0.56 7.57e-12 Colonoscopy-negative controls vs population controls; TGCT cis rs1467026 0.584 rs9880453 chr3:12804060 C/T cg05775895 chr3:12838266 CAND2 0.71 7.25 0.55 3.89e-11 P wave duration; TGCT cis rs79387448 0.745 rs79107058 chr2:103164257 C/A cg09003973 chr2:102972529 NA 0.95 6.15 0.48 9.95e-9 Gut microbiota (bacterial taxa); TGCT cis rs74544699 0.826 rs3756074 chr4:74848065 G/C cg16072462 chr4:74847758 PF4 1.02 5.45 0.44 2.56e-7 Growth-regulated protein alpha levels; TGCT cis rs763121 0.853 rs3747172 chr22:39067524 A/G cg06022373 chr22:39101656 GTPBP1 0.77 7.46 0.56 1.35e-11 Menopause (age at onset); TGCT cis rs2562456 0.917 rs2681389 chr19:21692575 G/A cg01304269 chr19:21688519 ZNF429 -0.55 -4.59 -0.38 1.06e-5 Pain; TGCT cis rs921968 0.643 rs2556386 chr2:219534530 C/T cg02176678 chr2:219576539 TTLL4 -0.38 -5.47 -0.44 2.34e-7 Mean corpuscular hemoglobin concentration; TGCT cis rs3091242 0.933 rs35403885 chr1:25784551 G/A cg10117171 chr1:25599238 RHD 0.3 4.92 0.4 2.69e-6 Erythrocyte sedimentation rate; TGCT cis rs67478160 0.643 rs8005225 chr14:104300151 C/T cg26031613 chr14:104095156 KLC1 0.63 6.53 0.51 1.56e-9 Schizophrenia; TGCT cis rs559928 0.553 rs4930168 chr11:64173058 A/G cg12453748 chr11:64085041 PRDX5;TRMT112 0.58 5.16 0.42 9.57e-7 Inflammatory bowel disease;Crohn's disease;Ulcerative colitis; TGCT cis rs11696501 0.688 rs2281211 chr20:44312858 C/T cg11783356 chr20:44313418 WFDC10B -0.33 -4.49 -0.37 1.6e-5 Brain structure; TGCT cis rs9549367 0.773 rs9549717 chr13:113908826 A/G cg18105134 chr13:113819100 PROZ -0.35 -5.94 -0.47 2.68e-8 Platelet distribution width; TGCT cis rs2997447 0.761 rs112552200 chr1:26456947 G/A cg03844060 chr1:26490628 NA 0.27 4.44 0.37 2e-5 QRS complex (12-leadsum); TGCT cis rs68170813 0.559 rs10487271 chr7:106898458 T/C cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs75686122 0.892 rs769134 chr8:104653444 G/T cg04852977 chr8:104510831 NA 0.59 4.46 0.37 1.81e-5 Cocaine dependence; TGCT cis rs2836974 0.899 rs8127087 chr21:40544502 C/T cg11644478 chr21:40555479 PSMG1 1.04 10.81 0.7 1.38e-19 Cognitive function; TGCT cis rs7267979 0.816 rs422148 chr20:25512604 G/C cg14121845 chr20:25566513 NINL 0.46 4.76 0.39 5.36e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4808199 0.689 rs12979148 chr19:19406869 T/C cg03709012 chr19:19516395 GATAD2A 0.79 5.54 0.45 1.75e-7 Nonalcoholic fatty liver disease; TGCT cis rs11969893 0.649 rs12527901 chr6:101280435 G/A cg12253828 chr6:101329408 ASCC3 1.22 5.92 0.47 2.93e-8 Economic and political preferences (immigration/crime); TGCT cis rs4499344 0.730 rs259279 chr19:33161274 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.91 -10.19 -0.68 4.27e-18 Mean platelet volume; TGCT cis rs9311474 0.629 rs11709284 chr3:52559705 G/A cg07507251 chr3:52567010 NT5DC2 0.46 6.57 0.51 1.28e-9 Electroencephalogram traits; TGCT cis rs6952809 0.504 rs1978169 chr7:2434522 G/A cg23289794 chr7:2394357 EIF3B -0.83 -7.09 -0.54 8.92e-11 Multiple sclerosis; TGCT cis rs13217239 0.646 rs35691005 chr6:26972070 A/G cg05738196 chr6:26577821 NA 0.49 4.77 0.39 4.98e-6 Schizophrenia; TGCT cis rs7618915 0.547 rs10780035 chr3:52764624 C/T cg11041457 chr3:52719354 GNL3;PBRM1 0.62 6.14 0.48 1.03e-8 Bipolar disorder; TGCT cis rs4665809 0.652 rs12611790 chr2:26404221 C/T cg22920501 chr2:26401640 FAM59B -0.78 -6.16 -0.48 9.43e-9 Gut microbiome composition (summer); TGCT cis rs903263 0.965 rs11163903 chr1:84592805 G/A cg09664975 chr1:84543551 PRKACB 0.49 4.59 0.38 1.06e-5 Breast cancer (male); TGCT cis rs13108904 0.870 rs3733338 chr4:1241472 G/A cg05665937 chr4:1216051 CTBP1 0.23 4.59 0.38 1.06e-5 Obesity-related traits; TGCT cis rs7811142 0.830 rs7341507 chr7:99951315 A/G cg07160278 chr7:100027354 MEPCE;ZCWPW1 1.01 8.32 0.6 1.34e-13 Platelet count; TGCT cis rs7085104 0.513 rs619824 chr10:104581288 G/T cg05855489 chr10:104503620 C10orf26 0.58 5.4 0.44 3.31e-7 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs7945705 0.818 rs1988708 chr11:8882893 C/A cg21881798 chr11:8931708 C11orf17;ST5 -0.48 -5.5 -0.44 2.03e-7 Hemoglobin concentration; TGCT cis rs10931896 0.531 rs295118 chr2:201144004 C/T cg17644776 chr2:200775616 C2orf69 0.26 4.76 0.39 5.28e-6 Systolic blood pressure; TGCT cis rs60871478 0.636 rs4721834 chr7:896142 C/T cg00475322 chr7:917719 C7orf20 0.5 4.87 0.4 3.37e-6 Cerebrospinal P-tau181p levels; TGCT cis rs7949030 0.626 rs1061093 chr11:62334908 G/C cg11742103 chr11:62369870 EML3;MTA2 0.61 8.71 0.62 1.65e-14 Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction);Waist-to-hip ratio adjusted for body mass index; TGCT cis rs362272 0.524 rs2857982 chr4:3358665 G/A cg06533319 chr4:3265114 C4orf44 -0.28 -5.69 -0.46 8.58e-8 Serum sulfate level; TGCT cis rs78487399 0.731 rs13408697 chr2:43706244 T/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.39 -4.96 -0.41 2.24e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs10540 0.915 rs35389167 chr11:460765 A/G cg03352830 chr11:487213 PTDSS2 0.26 4.58 0.38 1.1e-5 Body mass index; TGCT cis rs6912958 0.630 rs4707377 chr6:88280332 C/T cg06598631 chr6:88300029 RARS2;ORC3L -0.54 -4.91 -0.4 2.78e-6 Monocyte percentage of white cells; TGCT cis rs2933343 0.649 rs1683786 chr3:128626952 T/C cg11901034 chr3:128598214 ACAD9 -0.64 -6.12 -0.48 1.16e-8 IgG glycosylation; TGCT cis rs644148 0.836 rs2686776 chr19:45000366 T/C cg15540054 chr19:45004280 ZNF180 -0.66 -5.36 -0.43 3.83e-7 Personality dimensions; TGCT cis rs2739330 0.731 rs5751792 chr22:24401542 G/A cg20007245 chr22:24372913 LOC391322 -0.78 -8.52 -0.61 4.64e-14 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9357506 1.000 rs9296491 chr6:46315285 C/T cg21115430 chr6:46460003 NA -0.26 -5.16 -0.42 9.6e-7 Body mass index; TGCT cis rs9447004 0.584 rs12215671 chr6:74435607 T/C cg23004174 chr6:74404879 CD109 0.22 4.69 0.39 6.96e-6 Blood protein levels;Calcium levels; TGCT cis rs2239785 0.920 rs78523 chr22:36663248 C/T cg15716373 chr22:36655542 APOL1 0.45 5.2 0.42 8.01e-7 Glomerulosclerosis; TGCT cis rs6988636 1.000 rs28694222 chr8:124195017 C/T cg23067535 chr8:124195133 FAM83A -0.35 -5.22 -0.42 7.34e-7 Urinary uromodulin levels; TGCT cis rs9611565 0.765 rs202663 chr22:41812819 T/C cg06481639 chr22:41940642 POLR3H 0.6 5.48 0.44 2.23e-7 Vitiligo; TGCT cis rs9443645 0.901 rs9359354 chr6:79590385 A/G cg09184832 chr6:79620586 NA -0.49 -5.29 -0.43 5.29e-7 Intelligence (multi-trait analysis); TGCT cis rs2739330 0.828 rs5760108 chr22:24252668 G/T cg02953382 chr22:24373134 LOC391322 -0.76 -7.83 -0.58 1.84e-12 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs735396 1.000 rs1169313 chr12:121442670 C/T cg02403541 chr12:121454288 C12orf43 -0.65 -6.3 -0.49 4.8e-9 N-glycan levels; TGCT cis rs7432375 1.000 rs940174 chr3:136309710 T/C cg12473912 chr3:136751656 NA 0.34 4.85 0.4 3.55e-6 Neuroticism;Schizophrenia;Autism spectrum disorder or schizophrenia; TGCT cis rs4478858 0.775 rs59865338 chr1:31706643 A/G cg00250761 chr1:31883323 NA -0.31 -5.6 -0.45 1.34e-7 Alcohol dependence; TGCT cis rs7552404 0.765 rs1251078 chr1:76189488 C/G cg10523679 chr1:76189770 ACADM -0.98 -13.66 -0.78 1.69e-26 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs11112613 0.595 rs871219 chr12:105938519 C/A cg03607813 chr12:105948248 NA 0.46 5.36 0.43 3.88e-7 Corrected insulin response;Corrected insulin response adjusted for insulin sensitivity index; TGCT cis rs7618915 0.547 rs4687548 chr3:52666650 A/T cg05573699 chr3:52720067 GNL3;PBRM1 -0.47 -4.48 -0.37 1.66e-5 Bipolar disorder; TGCT cis rs6586163 0.872 rs7910660 chr10:90743197 G/A cg03111039 chr10:90751583 FAS;ACTA2 -0.38 -4.7 -0.39 6.86e-6 Chronic lymphocytic leukemia; TGCT cis rs12643440 0.574 rs12651694 chr4:17139359 G/A cg22650099 chr4:17144496 NA -0.46 -4.7 -0.39 6.79e-6 Metabolite levels (Pyroglutamine); TGCT cis rs2013441 1.000 rs2703806 chr17:20108239 A/T cg18979559 chr17:20280153 CCDC144C -0.44 -4.61 -0.38 9.78e-6 Obesity-related traits; TGCT cis rs3754214 0.836 rs12023277 chr1:150466737 A/G cg09579323 chr1:150459698 TARS2 0.52 4.58 0.38 1.12e-5 Cerebrospinal fluid biomarker levels; TGCT cis rs7246657 0.722 rs3829688 chr19:38077100 T/C cg03611452 chr19:38183253 ZNF781 0.58 4.64 0.38 8.62e-6 Coronary artery calcification; TGCT cis rs36051895 0.664 rs7851455 chr9:5100501 G/C cg02405213 chr9:5042618 JAK2 -0.77 -10.92 -0.7 7.16e-20 Pediatric autoimmune diseases; TGCT cis rs9837602 0.507 rs6803204 chr3:99680874 G/A cg07805332 chr3:99536008 MIR548G;C3orf26 0.62 6.98 0.53 1.6e-10 Breast cancer; TGCT cis rs10089 1.000 rs13355233 chr5:127425350 A/G cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.84 -8.19 -0.59 2.7e-13 Ileal carcinoids; TGCT cis rs55883249 1.000 rs11692112 chr2:9723732 G/T cg23886495 chr2:9695866 ADAM17 0.77 4.69 0.39 7.19e-6 3-hydroxy-1-methylpropylmercapturic acid levels in smokers; TGCT cis rs9486719 0.857 rs11751075 chr6:97065751 G/A cg18709589 chr6:96969512 KIAA0776 -0.83 -6.46 -0.5 2.16e-9 Migraine;Coronary artery disease; TGCT cis rs35306767 0.903 rs11815185 chr10:923617 T/A cg20503657 chr10:835505 NA 0.74 10.3 0.68 2.41e-18 Eosinophil percentage of granulocytes; TGCT cis rs9911578 0.935 rs302873 chr17:56769481 C/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.26 -0.49 5.86e-9 Intelligence (multi-trait analysis); TGCT cis rs11122272 0.668 rs2749712 chr1:231537751 T/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.66 -6.24 -0.49 6.42e-9 Hemoglobin concentration; TGCT cis rs10207628 1.000 rs10207628 chr2:127852021 C/G cg21679674 chr2:128283815 IWS1 -0.67 -4.68 -0.39 7.43e-6 Psychosis and Alzheimer's disease; TGCT cis rs1055129 0.560 rs2608880 chr17:73938957 C/T cg08125733 chr17:73851984 WBP2 0.57 5.29 0.43 5.29e-7 White matter hyperintensity burden; TGCT cis rs10504229 0.724 rs73603871 chr8:58107612 A/G cg08280861 chr8:58055591 NA 0.4 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs80282103 0.571 rs10047269 chr10:1103058 G/A cg08668510 chr10:1095578 IDI1 1.01 4.51 0.38 1.48e-5 Glomerular filtration rate (creatinine); TGCT cis rs6430585 0.583 rs12472293 chr2:136648077 T/C cg07169764 chr2:136633963 MCM6 1.23 11.98 0.73 1.9e-22 Corneal structure; TGCT trans rs4332037 0.851 rs28728306 chr7:1961814 C/A cg10840412 chr1:235813424 GNG4 1.05 8.44 0.6 7.18e-14 Bipolar disorder; TGCT cis rs6725041 0.819 rs1521645 chr2:213091216 A/G cg20637307 chr2:213403960 ERBB4 -0.52 -4.6 -0.38 1.02e-5 QT interval (ambient particulate matter interaction); TGCT cis rs7412746 0.611 rs10888391 chr1:150729983 G/A cg09365446 chr1:150670422 GOLPH3L 0.33 4.78 0.39 4.8e-6 Melanoma; TGCT cis rs950776 0.642 rs61630816 chr15:78965866 T/C cg21242079 chr15:79101063 ADAMTS7 -0.31 -4.71 -0.39 6.54e-6 Sudden cardiac arrest; TGCT cis rs644799 0.672 rs11021307 chr11:95501407 C/T cg25622487 chr11:95524042 FAM76B;CEP57 0.79 8.26 0.6 1.89e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs2013441 1.000 rs11871945 chr17:20206883 A/G cg23224458 chr17:20280056 CCDC144C -0.41 -4.88 -0.4 3.25e-6 Obesity-related traits; TGCT cis rs2836974 0.563 rs6517522 chr21:40553845 T/C cg11644478 chr21:40555479 PSMG1 0.77 7.84 0.58 1.78e-12 Cognitive function; TGCT trans rs7726839 0.540 rs3792720 chr5:643028 T/G cg25482853 chr8:67687455 SGK3 1.19 10.3 0.68 2.4e-18 Obesity-related traits; TGCT cis rs1843834 0.505 rs940317 chr2:225358118 C/T cg12698349 chr2:225449008 CUL3 0.78 6.41 0.5 2.77e-9 IgE levels in asthmatics (D.p. specific); TGCT cis rs1784581 0.588 rs9346893 chr6:162417511 C/G cg17173639 chr6:162384350 PARK2 0.4 6.6 0.51 1.07e-9 Itch intensity from mosquito bite; TGCT cis rs8077889 0.956 rs6503476 chr17:41850163 C/T cg26893861 chr17:41843967 DUSP3 1.1 13.81 0.78 7.45e-27 Triglycerides; TGCT cis rs7226408 0.948 rs11665195 chr18:34389940 T/A cg06757138 chr18:34340585 FHOD3 0.26 4.79 0.4 4.62e-6 Obesity-related traits; TGCT cis rs2836633 0.859 rs8132069 chr21:40032611 T/C cg12884169 chr21:40033163 ERG 0.44 4.64 0.38 8.84e-6 Coronary artery disease; TGCT cis rs4076764 0.914 rs6704467 chr1:163364512 A/G cg24596788 chr1:163392923 NA -0.17 -4.9 -0.4 2.99e-6 Motion sickness; TGCT trans rs7618501 1.000 rs3749241 chr3:49744392 A/G cg21659725 chr3:3221576 CRBN -0.99 -15.57 -0.81 5.76e-31 Intelligence (multi-trait analysis); TGCT cis rs7226408 0.802 rs11081969 chr18:34483191 C/T cg06757138 chr18:34340585 FHOD3 0.27 5.42 0.44 3.04e-7 Obesity-related traits; TGCT cis rs7147624 1.000 rs7153497 chr14:65998415 A/G cg03016385 chr14:66212404 NA -0.51 -7.09 -0.54 8.85e-11 Chronic obstructive pulmonary disease-related biomarkers; TGCT cis rs9926296 0.562 rs4785725 chr16:89893243 A/G cg08627397 chr16:89984028 MC1R -0.3 -4.78 -0.39 4.93e-6 Vitiligo; TGCT cis rs9644630 0.930 rs6586839 chr8:19365543 A/T cg01280390 chr8:19363452 CSGALNACT1 -0.27 -4.68 -0.39 7.47e-6 Oropharynx cancer; TGCT cis rs12765878 0.564 rs2073338 chr10:105642803 A/C cg11005552 chr10:105648138 OBFC1 -0.41 -6.3 -0.49 4.67e-9 Coronary artery disease; TGCT cis rs1552244 0.752 rs9867091 chr3:10043429 T/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.46 -6.7 -0.52 6.44e-10 Alzheimer's disease; TGCT cis rs8033133 0.602 rs1549477 chr15:25332118 C/T cg14481604 chr15:25334117 SNORD116-22 -0.25 -5.55 -0.45 1.63e-7 Blood osmolality (transformed sodium); TGCT cis rs6089584 0.566 rs2146852 chr20:60616492 T/G cg13770153 chr20:60521292 NA -0.39 -4.77 -0.39 5.17e-6 Body mass index; TGCT cis rs344364 0.511 rs56077812 chr16:1948870 T/G cg09830162 chr16:1889614 FAHD1;C16orf73 -0.45 -5.08 -0.42 1.35e-6 Glomerular filtration rate in chronic kidney disease; TGCT cis rs1008375 0.966 rs6813375 chr4:17649499 T/G cg18681998 chr4:17616180 MED28 1.06 12.43 0.74 1.57e-23 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs35883536 1.000 rs4908087 chr1:101088594 C/T cg06223162 chr1:101003688 GPR88 0.29 4.56 0.38 1.22e-5 Monocyte count; TGCT cis rs6860806 0.507 rs272891 chr5:131664394 G/T cg24060327 chr5:131705240 SLC22A5 -0.73 -7.69 -0.57 3.82e-12 Breast cancer; TGCT cis rs28386778 0.797 rs4968664 chr17:61851366 C/G cg25654072 chr17:61904446 PSMC5;FTSJ3 0.57 5.34 0.43 4.23e-7 Prudent dietary pattern; TGCT cis rs6669072 0.647 rs698274 chr1:91244177 A/G cg08895590 chr1:91227319 NA -0.34 -4.51 -0.38 1.47e-5 Cognitive function; TGCT cis rs11203032 0.831 rs4933494 chr10:90917892 T/A cg16672925 chr10:90967113 CH25H 0.81 4.94 0.41 2.44e-6 Heart failure; TGCT cis rs7605378 0.528 rs812760 chr2:200724372 C/T cg17644776 chr2:200775616 C2orf69 0.34 7.44 0.56 1.48e-11 Osteoporosis; TGCT cis rs832540 0.966 rs252923 chr5:56205662 T/G cg12311346 chr5:56204834 C5orf35 -0.52 -5.67 -0.45 9.59e-8 Coronary artery disease; TGCT cis rs854765 0.663 rs1108648 chr17:17750558 G/A cg24612305 chr17:17875800 TOM1L2;LRRC48 -0.73 -7.04 -0.53 1.17e-10 Total body bone mineral density; TGCT cis rs5769707 0.967 rs763126 chr22:49988574 G/T cg20744362 chr22:50050164 C22orf34 -0.28 -4.6 -0.38 1.04e-5 Monocyte count;Monocyte percentage of white cells; TGCT cis rs597539 0.617 rs669659 chr11:68635623 G/C cg21963583 chr11:68658836 MRPL21 0.36 6.17 0.48 9.01e-9 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs873946 0.618 rs12775767 chr10:134545628 C/T cg04744514 chr10:134541379 INPP5A 0.25 4.49 0.37 1.58e-5 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs9299 0.502 rs4793944 chr17:46667304 C/T cg25032089 chr17:46643351 HOXB3 -0.39 -4.88 -0.4 3.24e-6 Obesity; TGCT cis rs12497850 0.805 rs6446198 chr3:49007638 T/A cg05785598 chr3:49045655 WDR6 0.37 4.83 0.4 3.94e-6 Parkinson's disease; TGCT cis rs28386778 0.897 rs3744293 chr17:61841788 T/A cg06896619 chr17:61851486 DDX42;CCDC47 -0.49 -4.67 -0.39 7.73e-6 Prudent dietary pattern; TGCT trans rs10506458 0.915 rs60094497 chr12:63394838 T/G cg03429785 chr15:59498649 MYO1E;LDHAL6B -0.47 -7.58 -0.56 6.97e-12 Hemostatic factors and hematological phenotypes; TGCT cis rs17376456 0.825 rs12716453 chr5:93271697 T/C cg21475434 chr5:93447410 FAM172A 0.65 4.47 0.37 1.72e-5 Diabetic retinopathy; TGCT cis rs2797160 0.547 rs4144549 chr6:125945251 C/G cg05901451 chr6:126070800 HEY2 0.6 4.99 0.41 2.03e-6 Endometrial cancer; TGCT cis rs3812049 0.784 rs3749748 chr5:127350549 C/T cg25462716 chr5:127418816 SLC12A2;FLJ33630 -0.59 -5.43 -0.44 2.91e-7 Lymphocyte counts;Red cell distribution width; TGCT cis rs8013055 0.796 rs8005568 chr14:105971794 A/G cg19700328 chr14:106028568 NA -0.56 -6.29 -0.49 5.01e-9 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis); TGCT cis rs4783244 0.897 rs12598679 chr16:82651205 G/A cg09415485 chr16:82663111 CDH13 -0.25 -4.81 -0.4 4.29e-6 Adiponectin levels; TGCT cis rs250677 0.687 rs2963484 chr5:148451127 A/T cg23229984 chr5:148520753 ABLIM3 0.21 4.89 0.4 3.11e-6 Breast cancer; TGCT cis rs2404602 0.735 rs1607017 chr15:76726465 G/T cg22467129 chr15:76604101 ETFA 0.53 5.65 0.45 1.04e-7 Blood metabolite levels; TGCT cis rs11677370 0.574 rs11686118 chr2:3854938 C/T cg17052675 chr2:3827356 NA -0.41 -6.46 -0.5 2.19e-9 Type 2 diabetes; TGCT cis rs9534288 0.731 rs4942461 chr13:46551023 C/T cg15192986 chr13:46630673 CPB2 -0.53 -7.66 -0.57 4.65e-12 Blood protein levels; TGCT cis rs514406 0.698 rs1672913 chr1:53408326 A/T cg27535305 chr1:53392650 SCP2 -0.28 -5.74 -0.46 6.91e-8 Monocyte count; TGCT cis rs514406 0.571 rs11206004 chr1:53210958 G/A cg01802117 chr1:53393560 SCP2 0.46 5.51 0.44 1.95e-7 Monocyte count; TGCT cis rs478304 0.934 rs506853 chr11:65521247 C/T cg27068330 chr11:65405492 SIPA1 0.74 7.41 0.55 1.67e-11 Acne (severe); TGCT cis rs28595532 0.920 rs115506655 chr4:119757667 A/G cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs62185668 0.575 rs1107574 chr20:10931651 A/T cg17778165 chr20:10414372 MKKS -0.54 -4.84 -0.4 3.75e-6 Urinary bladder cancer; TGCT cis rs2354432 0.556 rs7516165 chr1:146866418 G/T cg25205988 chr1:146714368 CHD1L 1.32 5.88 0.47 3.62e-8 Mitochondrial DNA levels; TGCT cis rs7296418 0.699 rs11057254 chr12:123794581 A/C cg00376283 chr12:123451042 ABCB9 0.62 5.32 0.43 4.7e-7 Platelet count; TGCT cis rs9325144 0.560 rs61929893 chr12:38653366 G/A cg26384229 chr12:38710491 ALG10B -0.66 -6.0 -0.47 2.06e-8 Morning vs. evening chronotype; TGCT cis rs10946940 0.896 rs12208078 chr6:27498581 G/A cg10876282 chr6:28092338 ZSCAN16 -0.46 -4.6 -0.38 1.04e-5 Systemic lupus erythematosus; TGCT cis rs1371867 0.875 rs1788178 chr8:101332518 A/C cg06002616 chr8:101225028 SPAG1 -0.56 -6.58 -0.51 1.2e-9 Atrioventricular conduction; TGCT cis rs12681287 0.752 rs4282548 chr8:87270792 A/T cg27223183 chr8:87520930 FAM82B -0.8 -5.54 -0.45 1.71e-7 Caudate activity during reward; TGCT cis rs7618915 0.571 rs1961959 chr3:52585760 G/C cg11041457 chr3:52719354 GNL3;PBRM1 0.63 6.23 0.49 6.56e-9 Bipolar disorder; TGCT cis rs7523273 0.597 rs11118612 chr1:207979577 T/A cg22525895 chr1:207977042 MIR29B2 -0.44 -6.49 -0.5 1.88e-9 Schizophrenia; TGCT cis rs611744 0.647 rs2594357 chr8:109255989 A/G cg21045802 chr8:109455806 TTC35 0.7 6.74 0.52 5.23e-10 Dupuytren's disease; TGCT cis rs6840360 0.593 rs2175409 chr4:152701656 A/G cg17479576 chr4:152424074 FAM160A1 -0.54 -5.42 -0.44 2.99e-7 Intelligence (multi-trait analysis); TGCT cis rs826838 0.654 rs7977738 chr12:38722460 G/A cg26384229 chr12:38710491 ALG10B 0.64 6.0 0.47 2.01e-8 Heart rate; TGCT cis rs6815814 0.950 rs5743593 chr4:38802913 A/G cg02016764 chr4:38805732 TLR1 -0.36 -5.88 -0.47 3.5e-8 Breast cancer; TGCT cis rs3785574 0.927 rs2854183 chr17:61968002 C/T cg01411255 chr17:61851458 DDX42;CCDC47 1.04 11.55 0.72 2.13e-21 Height; TGCT cis rs10875746 0.669 rs10875767 chr12:48599257 A/C cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT cis rs1577917 0.545 rs7755958 chr6:86488511 G/C cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A 0.62 5.22 0.42 7.39e-7 Response to antipsychotic treatment; TGCT cis rs55794721 0.509 rs4649085 chr1:25778832 G/A cg10117171 chr1:25599238 RHD -0.32 -5.22 -0.42 7.32e-7 Plateletcrit;Mean corpuscular volume; TGCT cis rs1775715 0.737 rs1541260 chr10:32105570 C/T cg14930904 chr10:32216787 ARHGAP12 0.52 5.07 0.41 1.38e-6 Bipolar disorder with mood-incongruent psychosis; TGCT cis rs2147959 0.700 rs12725863 chr1:228630986 C/T cg22700015 chr1:228743131 NA -0.57 -4.53 -0.38 1.35e-5 Adult asthma; TGCT cis rs7830933 0.780 rs11986562 chr8:23609098 T/C cg04349084 chr8:23602677 NA 0.26 5.22 0.42 7.33e-7 Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction);Waist circumference adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction);Waist-to-hip ratio adjusted for body mass index;Waist circumference adjusted for body mass index;Waist-to-hip ratio adjusted for BMI in non-smokers;Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction);Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);Waist circumference adjusted for BMI in active individuals;Waist circumference adjusted for BMI in non-smokers; TGCT cis rs7267979 0.966 rs910996 chr20:25264196 A/G cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs4819052 0.851 rs2838842 chr21:46669217 C/T cg19498844 chr21:46707878 POFUT2;LOC642852 0.79 7.06 0.54 1.04e-10 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs11190604 1.000 rs7084810 chr10:102297546 A/G cg23241863 chr10:102295624 HIF1AN 0.69 5.1 0.42 1.24e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs6938 0.534 rs12913293 chr15:75184458 G/C cg10253484 chr15:75165896 SCAMP2 -0.55 -5.06 -0.41 1.45e-6 Breast cancer; TGCT cis rs873946 0.586 rs3793684 chr10:134568645 G/A cg17054783 chr10:134559939 INPP5A 0.24 4.83 0.4 3.92e-6 Gestational age at birth in labor-initiated deliveries (child effect);Gestational age at birth (child effect); TGCT cis rs35306767 0.715 rs12777801 chr10:1036285 T/A cg20503657 chr10:835505 NA 0.63 6.97 0.53 1.64e-10 Eosinophil percentage of granulocytes; TGCT cis rs9581857 0.579 rs3759434 chr13:27997700 A/C cg22138327 chr13:27999177 GTF3A 0.87 7.09 0.54 8.89e-11 Psychosis proneness (hypomanic personality scale and perceptual aberration scale); TGCT cis rs11785400 0.793 rs11785012 chr8:143748355 G/A cg24634471 chr8:143751801 JRK 0.55 5.38 0.44 3.52e-7 Schizophrenia; TGCT cis rs7193541 0.510 rs79473128 chr16:74589192 G/A cg01733217 chr16:74700730 RFWD3 0.63 5.27 0.43 5.76e-7 Multiple myeloma; TGCT cis rs7666738 0.544 rs35160902 chr4:98974690 A/T cg18180107 chr4:99064573 C4orf37 0.55 5.0 0.41 1.89e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs12497850 0.931 rs6446196 chr3:49004723 A/G cg18654377 chr3:49208889 KLHDC8B -0.42 -5.42 -0.44 2.97e-7 Parkinson's disease; TGCT cis rs10984561 0.881 rs917709 chr9:122249535 C/T cg14242995 chr9:122249943 NA 0.75 6.12 0.48 1.16e-8 Pulmonary function decline; TGCT cis rs6547741 1.000 rs1080060 chr2:27768808 T/A cg27432699 chr2:27873401 GPN1 0.18 4.66 0.39 8.09e-6 Oral cavity cancer; TGCT cis rs10782582 0.593 rs11164042 chr1:76178440 G/A cg03433033 chr1:76189801 ACADM -0.65 -7.42 -0.55 1.59e-11 Daytime sleep phenotypes; TGCT cis rs12220898 0.619 rs10735221 chr10:50483563 G/A cg09603381 chr10:49954066 WDFY4 0.38 4.45 0.37 1.88e-5 Inflammatory biomarkers; TGCT cis rs9611565 0.694 rs202637 chr22:41853928 A/G cg03806693 chr22:41940476 POLR3H 1.15 11.99 0.73 1.85e-22 Vitiligo; TGCT trans rs12599106 0.792 rs76039834 chr16:34598453 G/A cg11235426 chr6:292522 DUSP22 -0.65 -6.78 -0.52 4.32e-10 Menopause (age at onset); TGCT cis rs4478858 0.684 rs10798839 chr1:31731758 C/G cg00250761 chr1:31883323 NA -0.25 -4.52 -0.38 1.45e-5 Alcohol dependence; TGCT cis rs3829109 0.502 rs4320648 chr9:139294271 G/A cg13741927 chr9:139327495 INPP5E -0.24 -5.18 -0.42 8.84e-7 Peak insulin response;Acute insulin response; TGCT cis rs2032447 0.839 rs199751 chr6:26015583 T/C cg12310025 chr6:25882481 NA -0.65 -5.82 -0.46 4.61e-8 Intelligence (multi-trait analysis); TGCT cis rs600231 0.708 rs2957269 chr11:65243007 C/G cg17120908 chr11:65337727 SSSCA1 -0.55 -5.14 -0.42 1.03e-6 Bone mineral density; TGCT cis rs78487399 0.908 rs74501107 chr2:43806012 A/C cg04879876 chr2:43453558 ZFP36L2;LOC100129726 0.66 4.67 0.39 7.66e-6 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs597539 0.652 rs1249474 chr11:68654774 C/T cg21963583 chr11:68658836 MRPL21 0.33 5.38 0.43 3.59e-7 Coronary artery calcified atherosclerotic plaque score in type 2 diabetes; TGCT cis rs78487399 0.808 rs6752448 chr2:43682596 G/C cg06169590 chr2:43455088 ZFP36L2;LOC100129726 -0.44 -5.24 -0.43 6.79e-7 Myeloid white cell count;Granulocyte count;Sum neutrophil eosinophil counts;Sum basophil neutrophil counts;Inflammatory bowel disease; TGCT cis rs6089829 0.962 rs7273930 chr20:61666017 G/A cg18188782 chr20:61659543 NA 0.47 5.67 0.45 9.65e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs2832191 0.692 rs2245517 chr21:30357968 C/T cg08807101 chr21:30365312 RNF160 0.64 5.92 0.47 3e-8 Dental caries; TGCT cis rs12477438 0.798 rs4324365 chr2:99623845 T/G cg26064155 chr2:99771622 LIPT1;TSGA10 -0.66 -5.87 -0.47 3.74e-8 Chronic sinus infection; TGCT cis rs28386778 0.799 rs2665802 chr17:61995030 A/T cg06873352 chr17:61820015 STRADA -0.48 -5.49 -0.44 2.15e-7 Prudent dietary pattern; TGCT cis rs477895 0.713 rs11600867 chr11:63972052 T/A cg23719950 chr11:63933701 MACROD1 -0.7 -5.71 -0.46 7.81e-8 Mean platelet volume; TGCT cis rs76935404 0.899 rs73034465 chr19:41419075 A/G cg19493303 chr19:41414353 NA 0.42 5.11 0.42 1.17e-6 nicotine metabolite ratio in current smokers; TGCT cis rs9948 0.521 rs62156206 chr2:97357108 G/A cg01990225 chr2:97406019 LMAN2L -1.01 -5.14 -0.42 1.04e-6 Erectile dysfunction and prostate cancer treatment; TGCT cis rs2070488 0.861 rs2067082 chr3:38438182 C/G cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.91 9.65 0.65 8.88e-17 Electrocardiographic conduction measures; TGCT cis rs7582180 0.764 rs920269 chr2:100918363 G/A cg08017756 chr2:100939284 LONRF2 -0.32 -5.31 -0.43 4.89e-7 Intelligence (multi-trait analysis); TGCT cis rs7552404 1.000 rs11163924 chr1:76132070 A/C cg10523679 chr1:76189770 ACADM -0.92 -10.45 -0.68 1.04e-18 Blood metabolite levels;Acylcarnitine levels; TGCT cis rs6424115 0.862 rs34845821 chr1:24066486 C/T cg15997130 chr1:24165203 NA -0.66 -6.1 -0.48 1.24e-8 Immature fraction of reticulocytes; TGCT cis rs9549367 0.713 rs4907599 chr13:113861441 C/T cg09473364 chr13:112927190 NA 0.29 4.54 0.38 1.31e-5 Platelet distribution width; TGCT cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg05368731 chr17:41323189 NBR1 1.22 14.73 0.8 5.05e-29 Menopause (age at onset); TGCT cis rs12579753 0.913 rs7965664 chr12:82237340 G/T cg07988820 chr12:82153109 PPFIA2 -0.58 -6.25 -0.49 6.15e-9 Resting heart rate; TGCT cis rs9926296 0.533 rs12102297 chr16:89812762 C/A cg04287289 chr16:89883240 FANCA 0.92 11.34 0.71 6.88e-21 Vitiligo; TGCT cis rs12367572 0.965 rs10785539 chr12:45233023 G/C cg04608330 chr12:45269318 NELL2 -0.53 -5.17 -0.42 9.2e-7 Gut microbiome composition (summer); TGCT cis rs73058052 1.000 rs3760707 chr19:50084454 T/C cg09250473 chr19:50168907 IRF3;BCL2L12 0.84 6.33 0.49 4.16e-9 Fibrinogen levels; TGCT cis rs9926296 0.656 rs11861084 chr16:89875710 G/T cg03388025 chr16:89894329 SPIRE2 -0.37 -5.43 -0.44 2.79e-7 Vitiligo; TGCT cis rs1062177 1.000 rs12518722 chr5:151231460 A/G cg12924095 chr5:151150029 G3BP1 0.35 5.05 0.41 1.53e-6 Preschool internalizing problems; TGCT cis rs11190604 0.790 rs11190535 chr10:102197441 A/T cg16005271 chr10:102321736 NA 0.46 4.68 0.39 7.39e-6 Palmitoleic acid (16:1n-7) levels; TGCT cis rs4845570 1.000 rs1054479 chr1:151746079 A/T cg07092448 chr1:151763213 TDRKH -1.12 -8.18 -0.59 2.84e-13 Coronary artery disease; TGCT cis rs11190604 0.767 rs12360395 chr10:102194074 A/T cg16342193 chr10:102329863 NA -0.41 -5.2 -0.42 8.01e-7 Palmitoleic acid (16:1n-7) levels; TGCT cis rs807669 1.000 rs807669 chr22:19154522 T/C cg02655711 chr22:19163373 SLC25A1 0.39 9.14 0.63 1.53e-15 Metabolite levels; TGCT cis rs28595532 0.920 rs56124677 chr4:119772213 C/T cg14228332 chr4:119757509 SEC24D 1.23 7.05 0.53 1.13e-10 Cannabis dependence symptom count; TGCT cis rs523522 0.962 rs9040 chr12:120900274 C/T cg12219531 chr12:120966889 COQ5 0.82 7.34 0.55 2.49e-11 High light scatter reticulocyte count; TGCT cis rs12142240 0.698 rs66575205 chr1:46814092 T/G cg14993813 chr1:46806288 NSUN4 -0.58 -4.76 -0.39 5.3e-6 Menopause (age at onset); TGCT cis rs6570726 0.764 rs4896821 chr6:145896181 G/A cg23711669 chr6:146136114 FBXO30 0.84 8.89 0.62 6.14e-15 Lobe attachment (rater-scored or self-reported); TGCT cis rs7811142 1.000 rs11761784 chr7:100039970 C/T cg00814883 chr7:100076585 TSC22D4 -0.9 -9.56 -0.65 1.5e-16 Platelet count; TGCT cis rs9911578 0.900 rs717828 chr17:56535932 A/G cg05425664 chr17:57184151 TRIM37 -0.63 -6.21 -0.49 7.48e-9 Intelligence (multi-trait analysis); TGCT cis rs36051895 0.732 rs7046736 chr9:5015732 C/A cg02405213 chr9:5042618 JAK2 -0.74 -9.93 -0.67 1.9e-17 Pediatric autoimmune diseases; TGCT cis rs2456568 0.548 rs7113080 chr11:93657520 G/A cg17595323 chr11:93583763 C11orf90 -0.43 -5.54 -0.45 1.7e-7 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7085104 0.632 rs7096475 chr10:104609676 A/G cg04362960 chr10:104952993 NT5C2 0.55 4.73 0.39 5.98e-6 Immature fraction of reticulocytes;Schizophrenia; TGCT cis rs801193 1.000 rs2707850 chr7:66203870 G/T cg00343986 chr7:65444356 GUSB 0.24 5.25 0.43 6.3e-7 Aortic root size; TGCT trans rs17471911 0.708 rs7919499 chr10:100793754 G/A cg03484267 chr2:207988651 KLF7 -0.52 -6.7 -0.52 6.49e-10 Neuroticism; TGCT cis rs6598955 0.671 rs17163751 chr1:26568698 A/G cg04990556 chr1:26633338 UBXN11 0.64 5.11 0.42 1.19e-6 Obesity-related traits; TGCT cis rs9611565 0.659 rs73178641 chr22:41952075 A/T cg06481639 chr22:41940642 POLR3H -0.76 -6.97 -0.53 1.65e-10 Vitiligo; TGCT cis rs9902453 0.833 rs7216631 chr17:28495112 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.73 6.9 0.53 2.37e-10 Coffee consumption (cups per day); TGCT cis rs2836974 0.899 rs34978594 chr21:40580003 C/T cg11644478 chr21:40555479 PSMG1 1.01 10.47 0.69 8.99e-19 Cognitive function; TGCT cis rs4722404 0.800 rs7809262 chr7:3141137 A/G cg17467898 chr7:2289054 NUDT1 0.18 4.71 0.39 6.48e-6 Atopic dermatitis; TGCT cis rs2241685 1.000 rs2241685 chr2:1925993 C/T cg21862353 chr2:1801628 MYT1L -0.51 -5.15 -0.42 9.86e-7 Attention deficit hyperactivity disorder; TGCT cis rs909674 0.818 rs5750830 chr22:39840828 C/A cg24399712 chr22:39784796 NA -1.04 -10.92 -0.7 7.31e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT cis rs422249 0.512 rs174561 chr11:61582708 T/C cg19610905 chr11:61596333 FADS2 -1.05 -11.51 -0.72 2.6e-21 Trans fatty acid levels; TGCT cis rs2243480 1.000 rs781142 chr7:65438778 C/T cg07424592 chr7:64974309 NA 1.33 7.68 0.57 4.1e-12 Diabetic kidney disease; TGCT cis rs763121 0.853 rs11704021 chr22:39074716 G/A cg06022373 chr22:39101656 GTPBP1 0.76 7.43 0.56 1.52e-11 Menopause (age at onset); TGCT cis rs67311347 1.000 rs6762251 chr3:40531136 A/G cg13683864 chr3:40499215 RPL14 1.12 11.68 0.72 1.05e-21 Renal cell carcinoma; TGCT cis rs4819052 1.000 rs733738 chr21:46666396 A/G cg06618935 chr21:46677482 NA 0.33 4.6 0.38 1.04e-5 Coronary artery calcified atherosclerotic plaque (90 or 130 HU threshold) in type 2 diabetes; TGCT cis rs910316 0.663 rs175034 chr14:75463687 T/G cg08847533 chr14:75593920 NEK9 -0.84 -8.91 -0.62 5.45e-15 Height; TGCT cis rs854765 0.964 rs854813 chr17:18003845 C/T cg09796270 chr17:17721594 SREBF1 -0.26 -5.22 -0.42 7.3e-7 Total body bone mineral density; TGCT cis rs9902453 0.791 rs3115100 chr17:28045744 T/C cg26525008 chr17:28256777 EFCAB5;SSH2 0.84 8.39 0.6 9.14e-14 Coffee consumption (cups per day); TGCT cis rs9399135 0.967 rs6919862 chr6:135352443 C/A cg24558204 chr6:135376177 HBS1L 0.48 4.77 0.39 5.14e-6 Red blood cell count; TGCT cis rs9549367 0.789 rs2287244 chr13:113887173 C/G cg18105134 chr13:113819100 PROZ 0.34 5.69 0.45 8.84e-8 Platelet distribution width; TGCT cis rs5760092 0.755 rs4585126 chr22:24270005 T/C cg25703541 chr22:24373054 LOC391322 0.82 6.92 0.53 2.13e-10 Urinary 1,3-butadiene metabolite levels in smokers; TGCT cis rs12681288 0.862 rs11996703 chr8:1009093 T/C cg04851639 chr8:1020857 NA -0.36 -6.29 -0.49 4.97e-9 Schizophrenia; TGCT cis rs9457247 0.534 rs7750593 chr6:167387359 C/G cg23791538 chr6:167370224 RNASET2 0.63 6.24 0.49 6.21e-9 Crohn's disease; TGCT cis rs35264875 0.851 rs7933746 chr11:68867722 A/G cg02660097 chr11:68866761 NA 0.3 4.71 0.39 6.5e-6 Blond vs. brown hair color; TGCT cis rs492146 0.765 rs423475 chr6:52844583 G/T cg06706454 chr6:52930286 FBXO9 -0.51 -4.66 -0.39 8.12e-6 Epilepsy (remission after treatment); TGCT cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg21724239 chr8:58056113 NA 0.39 5.19 0.42 8.42e-7 Developmental language disorder (linguistic errors); TGCT cis rs2439831 0.867 rs486301 chr15:43836949 G/A cg27015174 chr15:43622946 ADAL;LCMT2 0.84 5.73 0.46 7.33e-8 Lung cancer in ever smokers; TGCT cis rs12989701 0.877 rs12994718 chr2:127874226 T/A cg08168897 chr2:127865431 BIN1 0.5 5.34 0.43 4.28e-7 Alzheimer's disease (late onset); TGCT cis rs7267979 1.000 rs7019 chr20:25278278 C/T cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs6866344 0.570 rs11740283 chr5:178136440 T/C cg03877680 chr5:178157825 ZNF354A 0.76 6.54 0.51 1.47e-9 Neutrophil percentage of white cells; TGCT cis rs2032447 0.641 rs442601 chr6:25934524 G/A cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.79 7.56 0.56 7.67e-12 Intelligence (multi-trait analysis); TGCT cis rs4654899 0.865 rs61779075 chr1:21417027 T/C cg01072550 chr1:21505969 NA -0.47 -7.1 -0.54 8.54e-11 Superior frontal gyrus grey matter volume; TGCT cis rs12220238 1.000 rs11000941 chr10:76018301 A/G cg19889307 chr10:75911429 ADK;AP3M1 0.9 6.53 0.51 1.51e-9 Soluble interleukin-2 receptor subunit alpha; TGCT trans rs6089829 0.962 rs7273930 chr20:61666017 G/A cg13615516 chr5:77269221 NA 0.67 8.3 0.6 1.47e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs4824093 0.610 rs73443923 chr22:50285348 C/T cg26441486 chr22:50317300 CRELD2 0.41 4.78 0.39 4.81e-6 Amyotrophic lateral sclerosis (sporadic); TGCT cis rs806215 0.526 rs3757780 chr7:127435520 T/G cg11539674 chr7:127291444 SND1 -0.36 -4.6 -0.38 1.02e-5 Type 2 diabetes; TGCT cis rs10540 1.000 rs12794284 chr11:477623 C/T cg03934478 chr11:495069 RNH1 0.35 5.89 0.47 3.34e-8 Body mass index; TGCT cis rs10875746 0.624 rs10875777 chr12:48622071 T/C cg20731937 chr12:48336164 NA 0.59 4.52 0.38 1.45e-5 Longevity (90 years and older); TGCT cis rs17376456 0.877 rs28637444 chr5:93495548 C/T cg25358565 chr5:93447407 FAM172A 0.97 8.32 0.6 1.34e-13 Diabetic retinopathy; TGCT cis rs6952808 0.792 rs2056480 chr7:1954301 A/G cg04267008 chr7:1944627 MAD1L1 0.35 4.79 0.4 4.63e-6 Bipolar disorder and schizophrenia; TGCT cis rs17376456 0.825 rs7715562 chr5:93222034 C/T cg25358565 chr5:93447407 FAM172A -0.96 -8.07 -0.59 5.23e-13 Diabetic retinopathy; TGCT cis rs9341808 0.718 rs7740627 chr6:80916347 A/G cg08355045 chr6:80787529 NA 0.32 5.6 0.45 1.29e-7 Sitting height ratio; TGCT cis rs853679 0.550 rs1225598 chr6:28160799 T/G cg12963246 chr6:28129442 ZNF389 0.48 4.74 0.39 5.69e-6 Depression; TGCT cis rs478304 0.514 rs75601653 chr11:65483370 C/G cg27068330 chr11:65405492 SIPA1 -0.98 -9.26 -0.64 7.7e-16 Acne (severe); TGCT cis rs950169 0.580 rs17598114 chr15:85171317 C/T cg11189052 chr15:85197271 WDR73 0.73 6.1 0.48 1.27e-8 Schizophrenia; TGCT cis rs2836974 0.966 rs2836977 chr21:40666066 T/C cg11890956 chr21:40555474 PSMG1 1.1 12.28 0.74 3.66e-23 Cognitive function; TGCT cis rs1127311 0.905 rs6699729 chr1:154582896 A/T cg17218026 chr1:154582156 ADAR 0.31 7.7 0.57 3.72e-12 C-reactive protein levels or triglyceride levels (pleiotropy); TGCT cis rs853679 0.546 rs34295134 chr6:27828151 T/A cg01031101 chr6:28227091 NKAPL -0.49 -4.66 -0.39 8.09e-6 Depression; TGCT trans rs4332037 0.539 rs3823624 chr7:2110346 T/C cg25206134 chr2:45395956 NA 0.94 6.93 0.53 2e-10 Bipolar disorder; TGCT cis rs7769051 0.808 rs1467404 chr6:133090141 A/G cg07930552 chr6:133119739 C6orf192 -0.96 -5.15 -0.42 1.01e-6 Type 2 diabetes nephropathy; TGCT cis rs17076896 0.786 rs117391778 chr13:19931050 C/T cg00777926 chr13:20807375 GJB6 -0.37 -4.51 -0.38 1.5e-5 Coronary artery aneurysm in Kawasaki disease; TGCT cis rs9517320 0.534 rs61969451 chr13:99167654 A/T cg07423050 chr13:99094983 FARP1 -0.28 -5.67 -0.45 9.67e-8 Longevity; TGCT cis rs17122693 1.000 rs17122693 chr14:51084235 C/T cg04730355 chr14:51134070 SAV1 -1.14 -8.9 -0.62 5.62e-15 Cognitive performance; TGCT cis rs9486719 0.894 rs34826652 chr6:96899085 A/G cg06623918 chr6:96969491 KIAA0776 -1.01 -8.86 -0.62 7.18e-15 Migraine;Coronary artery disease; TGCT cis rs5750830 0.621 rs5750810 chr22:39792943 A/G cg01416388 chr22:39784598 NA -0.72 -6.98 -0.53 1.61e-10 Intelligence (multi-trait analysis); TGCT cis rs7666738 0.830 rs9998582 chr4:98938949 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1862618 0.853 rs832582 chr5:56177743 G/A cg20203395 chr5:56204925 C5orf35 -0.58 -4.87 -0.4 3.34e-6 Initial pursuit acceleration; TGCT cis rs2730260 0.537 rs73169248 chr7:158891742 T/G cg27122614 chr7:157913741 PTPRN2 0.42 4.47 0.37 1.74e-5 Myopia (pathological); TGCT cis rs546131 0.928 rs483976 chr11:34840167 C/G cg11058730 chr11:34937778 PDHX;APIP 0.51 4.57 0.38 1.18e-5 Lung disease severity in cystic fibrosis; TGCT cis rs7208859 0.673 rs11658344 chr17:29207745 G/T cg18442181 chr17:29233375 C17orf42 -0.79 -4.78 -0.39 4.95e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs951366 0.764 rs708725 chr1:205744138 G/T cg07167872 chr1:205819463 PM20D1 0.59 7.65 0.57 4.74e-12 Menarche (age at onset); TGCT cis rs57590327 0.555 rs13072957 chr3:81776242 A/G cg07356753 chr3:81810745 GBE1 0.77 7.2 0.54 5.1e-11 Extraversion; TGCT cis rs7726839 0.540 rs3792720 chr5:643028 T/G cg20362242 chr5:692897 TPPP 0.5 4.57 0.38 1.17e-5 Obesity-related traits; TGCT cis rs4711350 0.906 rs3957165 chr6:33784864 A/G cg18005901 chr6:33739558 LEMD2 0.59 6.08 0.48 1.37e-8 Schizophrenia; TGCT cis rs12681287 0.752 rs10435563 chr8:87266060 C/T cg27223183 chr8:87520930 FAM82B -0.81 -5.66 -0.45 9.9e-8 Caudate activity during reward; TGCT cis rs10464366 0.746 rs62442210 chr7:39146328 G/T cg18850127 chr7:39170497 POU6F2 0.3 6.61 0.51 1e-9 IgG glycosylation; TGCT cis rs5750830 0.594 rs5757650 chr22:39778419 A/G cg01416388 chr22:39784598 NA -0.61 -6.37 -0.5 3.28e-9 Intelligence (multi-trait analysis); TGCT cis rs617219 0.726 rs1275105 chr5:78444148 T/C cg09550809 chr5:78407562 BHMT 0.39 5.4 0.44 3.29e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs748404 0.604 rs2278857 chr15:43632549 T/C cg27015174 chr15:43622946 ADAL;LCMT2 0.46 4.44 0.37 1.98e-5 Lung cancer; TGCT cis rs7267979 0.586 rs6083776 chr20:25186116 G/A cg16686733 chr20:25566563 NINL 0.53 5.41 0.44 3.06e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs7647973 0.922 rs6809851 chr3:49309787 C/A cg07636037 chr3:49044803 WDR6 0.68 5.46 0.44 2.45e-7 Menarche (age at onset); TGCT cis rs1990950 0.605 rs7715241 chr5:156880770 G/A cg25387487 chr5:157003181 ADAM19 0.39 5.97 0.47 2.36e-8 Lung function (FEV1/FVC); TGCT cis rs2153535 0.580 rs2327064 chr6:8454052 C/T cg23788917 chr6:8435910 SLC35B3 0.6 5.52 0.44 1.88e-7 Motion sickness; TGCT cis rs116095464 0.558 rs9688045 chr5:254035 T/C cg22857025 chr5:266934 NA -0.34 -6.7 -0.52 6.65e-10 Breast cancer; TGCT cis rs2032447 1.000 rs2032447 chr6:26044369 A/G cg17711541 chr6:26124704 HIST1H2AC;HIST1H2BC -0.56 -5.61 -0.45 1.24e-7 Intelligence (multi-trait analysis); TGCT cis rs1403694 0.695 rs1836860 chr3:186436604 C/T cg12454167 chr3:186435060 KNG1 -0.52 -8.92 -0.63 5.02e-15 Blood protein levels; TGCT cis rs514475 0.526 rs17066649 chr6:137952694 T/C cg02673417 chr6:137105249 MAP3K5 0.29 4.45 0.37 1.88e-5 Inflammatory skin disease; TGCT cis rs62064224 0.546 rs62065495 chr17:30834617 T/C cg18200150 chr17:30822561 MYO1D 0.5 6.56 0.51 1.31e-9 Schizophrenia; TGCT cis rs6089829 0.962 rs2277769 chr20:61666805 C/T cg02380750 chr20:61661411 NA 0.33 5.84 0.46 4.23e-8 Prostate cancer (SNP x SNP interaction); TGCT cis rs13408808 0.606 rs7589079 chr2:168583144 C/T cg25427580 chr2:168675357 B3GALT1 0.39 4.71 0.39 6.58e-6 Obesity-related traits; TGCT cis rs3733631 1.000 rs28878597 chr4:104591916 A/G cg24090629 chr4:104641072 TACR3 -0.73 -5.72 -0.46 7.65e-8 Menarche (age at onset); TGCT cis rs7267979 1.000 rs2258066 chr20:25271326 C/T cg16686733 chr20:25566563 NINL 0.59 5.99 0.47 2.13e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs2836974 0.831 rs2836921 chr21:40516070 C/T cg06238570 chr21:40685208 BRWD1 0.58 5.11 0.42 1.16e-6 Cognitive function; TGCT cis rs11030122 0.673 rs4910869 chr11:4006438 C/T cg18678763 chr11:4115507 RRM1 -0.48 -5.88 -0.47 3.54e-8 Mean platelet volume;Platelet distribution width; TGCT cis rs546131 0.963 rs539044 chr11:34841542 G/T cg06937548 chr11:34938143 PDHX;APIP 0.58 5.24 0.43 6.72e-7 Lung disease severity in cystic fibrosis; TGCT cis rs10507380 0.824 rs75866904 chr13:27921765 C/T cg25543773 chr13:27185723 WASF3 0.34 4.83 0.4 3.97e-6 Electrocardiographic traits; TGCT cis rs9300255 0.739 rs1980252 chr12:123745178 C/G cg00376283 chr12:123451042 ABCB9 0.72 5.54 0.45 1.76e-7 Neutrophil percentage of white cells; TGCT cis rs7904368 0.806 rs7087360 chr10:16872337 C/A cg14835575 chr10:16859367 RSU1 0.66 6.35 0.5 3.62e-9 Ratio of the peak velocity of the mitral E-Wave divided by the peak velocity of the mitral A-wave.; TGCT cis rs8032315 0.895 rs4932370 chr15:91404705 A/G cg06330618 chr15:91428456 FES -0.18 -4.6 -0.38 1.02e-5 Autism spectrum disorder or schizophrenia; TGCT cis rs2880765 0.835 rs7169429 chr15:86036648 C/T cg13263323 chr15:86062960 AKAP13 -0.22 -4.73 -0.39 5.93e-6 Coronary artery disease; TGCT cis rs2070488 0.775 rs961179 chr3:38509618 G/A cg01465620 chr3:38496096 LOC100128640;ACVR2B 0.78 7.9 0.58 1.26e-12 Electrocardiographic conduction measures; TGCT cis rs3733585 0.673 rs6449156 chr4:9956712 G/C cg00071950 chr4:10020882 SLC2A9 -0.56 -6.72 -0.52 5.85e-10 Cleft plate (environmental tobacco smoke interaction); TGCT cis rs941873 0.805 rs10824747 chr10:81118464 T/C cg09469691 chr10:81107165 PPIF 0.5 4.96 0.41 2.27e-6 Height; TGCT cis rs7666738 0.830 rs1869897 chr4:98730997 C/T cg17366294 chr4:99064904 C4orf37 0.65 6.78 0.52 4.31e-10 Colonoscopy-negative controls vs population controls; TGCT cis rs11673344 0.562 rs6510580 chr19:37529354 C/T cg08039142 chr19:36980659 ZNF566 0.5 4.65 0.39 8.42e-6 Obesity-related traits; TGCT cis rs9467773 1.000 rs9467791 chr6:26562486 A/G cg05738196 chr6:26577821 NA -0.89 -12.76 -0.75 2.46e-24 Intelligence (multi-trait analysis); TGCT cis rs61884328 0.733 rs78998999 chr11:47228403 A/T cg13308137 chr11:47528955 CUGBP1 0.38 4.56 0.38 1.23e-5 Total body bone mineral density (age over 60); TGCT cis rs7819412 0.635 rs4841501 chr8:11000976 T/C cg03192020 chr8:11204681 TDH -0.51 -4.45 -0.37 1.88e-5 Triglycerides; TGCT cis rs9300255 0.602 rs1106241 chr12:123627016 T/C cg00376283 chr12:123451042 ABCB9 0.71 5.54 0.45 1.7e-7 Neutrophil percentage of white cells; TGCT cis rs2486288 0.656 rs11629807 chr15:45547037 T/C cg14582100 chr15:45693742 SPATA5L1 -0.46 -5.59 -0.45 1.38e-7 Glomerular filtration rate; TGCT cis rs7666738 0.791 rs34152299 chr4:98929862 G/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs11676348 0.846 rs7607437 chr2:219008392 A/G cg00012203 chr2:219082015 ARPC2 -0.51 -4.8 -0.4 4.48e-6 Ulcerative colitis; TGCT cis rs6921919 0.583 rs7764737 chr6:28354615 A/T cg18815343 chr6:28367644 ZSCAN12 -0.56 -5.32 -0.43 4.76e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs6088580 0.634 rs13041646 chr20:33082881 T/A cg06115741 chr20:33292138 TP53INP2 0.53 4.63 0.38 8.95e-6 Glomerular filtration rate (creatinine); TGCT cis rs6490294 0.904 rs11066111 chr12:112415179 A/T cg10833066 chr12:111807467 FAM109A 0.35 5.13 0.42 1.09e-6 Mean platelet volume; TGCT cis rs7246657 1.000 rs34544865 chr19:37801242 G/C cg18154014 chr19:37997991 ZNF793 0.94 6.41 0.5 2.74e-9 Coronary artery calcification; TGCT cis rs2932538 0.922 rs12138335 chr1:113122760 T/C cg22162597 chr1:113214053 CAPZA1 0.28 5.83 0.46 4.4e-8 Systolic blood pressure;Diastolic blood pressure;Hypertension;Blood pressure; TGCT cis rs9322193 0.923 rs11155674 chr6:150032247 T/C cg13206674 chr6:150067644 NUP43 0.52 4.51 0.38 1.5e-5 Lung cancer; TGCT cis rs1008375 0.932 rs11934968 chr4:17667766 A/G cg18681998 chr4:17616180 MED28 0.88 8.84 0.62 7.88e-15 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs9858542 0.953 rs7623659 chr3:49414791 C/T cg03060546 chr3:49711283 APEH -0.64 -5.61 -0.45 1.27e-7 Ulcerative colitis;Blood protein levels;Crohn's disease; TGCT cis rs2012796 0.785 rs61986599 chr14:81860917 G/A cg02996355 chr14:81879375 NA 0.56 5.52 0.44 1.92e-7 Night sleep phenotypes; TGCT cis rs6840360 0.571 rs718800 chr4:152549307 A/T cg17479576 chr4:152424074 FAM160A1 0.67 6.71 0.52 6.18e-10 Intelligence (multi-trait analysis); TGCT cis rs3803170 0.513 rs4766574 chr12:111832372 C/T cg10833066 chr12:111807467 FAM109A 0.35 5.1 0.42 1.23e-6 Mean corpuscular hemoglobin; TGCT cis rs3096299 0.933 rs2965824 chr16:89455306 A/G cg02187348 chr16:89574699 SPG7 0.49 4.66 0.39 7.93e-6 Multiple myeloma (IgH translocation); TGCT cis rs611744 0.967 rs628340 chr8:109189425 A/G cg21045802 chr8:109455806 TTC35 0.5 4.55 0.38 1.27e-5 Dupuytren's disease; TGCT cis rs1552244 0.816 rs13059144 chr3:10010197 A/C cg18598329 chr3:10140678 FANCD2;C3orf24 -0.47 -6.63 -0.51 9.04e-10 Alzheimer's disease; TGCT cis rs4689388 0.926 rs11725500 chr4:6293919 C/G cg00701064 chr4:6280414 WFS1 0.37 4.72 0.39 6.3e-6 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs11122272 0.735 rs2749711 chr1:231537543 G/A cg23162821 chr1:231664172 TSNAX-DISC1;TSNAX -0.68 -6.48 -0.5 1.93e-9 Hemoglobin concentration; TGCT cis rs6504663 0.525 rs557 chr17:48563234 C/T cg03168497 chr17:48586147 MYCBPAP 0.47 4.94 0.41 2.47e-6 Visceral fat; TGCT cis rs9660180 0.846 rs10907195 chr1:1713348 C/T cg23982607 chr1:1823379 GNB1 0.4 5.13 0.42 1.08e-6 Body mass index; TGCT trans rs564343 0.563 rs1642958 chr11:65821973 G/C cg26701943 chr11:108369231 KDELC2 -0.74 -6.9 -0.53 2.34e-10 Obesity (early onset extreme); TGCT cis rs28595532 0.841 rs115233595 chr4:119744214 T/C cg14228332 chr4:119757509 SEC24D 1.28 6.68 0.51 7.23e-10 Cannabis dependence symptom count; TGCT cis rs644799 0.710 rs12273579 chr11:95524421 G/A cg03916912 chr11:95522834 CEP57;FAM76B 0.79 8.65 0.61 2.18e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs11098499 0.954 rs1022145 chr4:120230979 A/G cg09307838 chr4:120376055 NA 0.64 5.93 0.47 2.79e-8 Corneal astigmatism; TGCT cis rs28595532 0.920 rs115372254 chr4:119771735 T/C cg21605333 chr4:119757512 SEC24D 1.51 8.99 0.63 3.38e-15 Cannabis dependence symptom count; TGCT cis rs7191439 0.858 rs2340973 chr16:88773396 G/A cg27087555 chr16:88793112 FAM38A -0.64 -7.52 -0.56 9.35e-12 Plateletcrit; TGCT cis rs4886920 0.563 rs4511491 chr15:78079304 A/G cg03457338 chr15:78040120 NA 0.18 4.51 0.38 1.48e-5 Neuroticism; TGCT cis rs6921919 0.583 rs3800328 chr6:28390843 C/T cg18815343 chr6:28367644 ZSCAN12 -0.53 -5.16 -0.42 9.45e-7 Autism spectrum disorder or schizophrenia; TGCT cis rs9811920 0.555 rs68092024 chr3:99691522 C/T cg07805332 chr3:99536008 MIR548G;C3orf26 0.58 6.76 0.52 4.85e-10 Axial length; TGCT cis rs250677 0.687 rs250672 chr5:148446110 A/G cg18129178 chr5:148520854 ABLIM3 -0.43 -6.29 -0.49 5.05e-9 Breast cancer; TGCT cis rs8017423 0.935 rs3737035 chr14:90745422 T/C cg04374321 chr14:90722782 PSMC1 -0.74 -7.09 -0.54 9.2e-11 Mortality in heart failure; TGCT cis rs2933343 0.951 rs1055128 chr3:128591048 C/T cg11901034 chr3:128598214 ACAD9 -0.64 -5.05 -0.41 1.56e-6 IgG glycosylation; TGCT cis rs9311474 0.508 rs3796353 chr3:52593230 C/T cg07507251 chr3:52567010 NT5DC2 0.47 6.63 0.51 9.08e-10 Electroencephalogram traits; TGCT cis rs67478160 0.619 rs1040813 chr14:104306696 T/C cg26031613 chr14:104095156 KLC1 -0.63 -6.53 -0.51 1.56e-9 Schizophrenia; TGCT cis rs10832963 0.686 rs11024743 chr11:18653712 A/G cg20219074 chr11:18656078 SPTY2D1 0.98 9.9 0.66 2.19e-17 Breast cancer; TGCT cis rs10838634 1.000 rs61897304 chr11:46809210 A/G cg18332754 chr11:46939436 LRP4 0.89 4.45 0.37 1.85e-5 Schizophrenia; TGCT cis rs17253792 0.822 rs79807559 chr14:56108117 G/A cg01858014 chr14:56050164 KTN1 -0.35 -4.5 -0.37 1.53e-5 Putamen volume; TGCT cis rs4886920 0.563 rs55726435 chr15:78071083 C/T cg25212270 chr15:78015279 NA -0.23 -4.75 -0.39 5.63e-6 Neuroticism; TGCT cis rs7917772 0.503 rs11191347 chr10:104351617 C/T cg11453585 chr10:104263688 ACTR1A;SUFU 0.8 8.21 0.59 2.44e-13 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs924607 0.966 rs1709554 chr5:637443 A/G cg18765565 chr5:669397 TPPP 0.58 6.07 0.48 1.45e-8 Vincristine-induced peripheral neuropathy in acute lymphoblastic leukemia; TGCT cis rs3796352 1.000 rs34244302 chr3:53102236 C/G cg27565382 chr3:53032988 SFMBT1 0.45 4.76 0.39 5.25e-6 Immune reponse to smallpox (secreted IL-2); TGCT cis rs10504229 1.000 rs74546828 chr8:58171678 A/G cg08280861 chr8:58055591 NA 0.36 4.96 0.41 2.23e-6 Developmental language disorder (linguistic errors); TGCT cis rs12681288 0.823 rs2701907 chr8:1003292 A/G cg04851639 chr8:1020857 NA -0.35 -6.22 -0.49 7.08e-9 Schizophrenia; TGCT cis rs7474896 0.583 rs11011341 chr10:37998500 G/A cg25427524 chr10:38739819 LOC399744 -0.31 -4.89 -0.4 3.01e-6 Obesity (extreme); TGCT cis rs7246657 0.722 rs35863684 chr19:38109777 C/T cg18154014 chr19:37997991 ZNF793 0.68 4.6 0.38 1.03e-5 Coronary artery calcification; TGCT cis rs4819852 1.000 rs7285377 chr22:19987202 G/T cg07821417 chr22:19972146 ARVCF 0.2 5.14 0.42 1.04e-6 Pulse pressure; TGCT cis rs9325144 0.647 rs1386018 chr12:39104360 C/T cg10518543 chr12:38710700 ALG10B -0.49 -4.55 -0.38 1.25e-5 Morning vs. evening chronotype; TGCT cis rs9952991 0.566 rs487273 chr18:12853458 T/G cg23598886 chr18:12777645 NA 0.57 5.05 0.41 1.51e-6 Inflammatory skin disease; TGCT cis rs7267979 1.000 rs6083805 chr20:25317356 T/C cg03522245 chr20:25566470 NINL -0.63 -6.8 -0.52 3.92e-10 Liver enzyme levels (alkaline phosphatase); TGCT cis rs8077889 0.703 rs231534 chr17:41945564 C/T cg26893861 chr17:41843967 DUSP3 -1.09 -10.35 -0.68 1.81e-18 Triglycerides; TGCT cis rs6750047 0.719 rs336035 chr2:38261467 A/G cg07380506 chr2:38303506 CYP1B1 -0.55 -4.87 -0.4 3.32e-6 Cutaneous malignant melanoma;Melanoma; TGCT cis rs17767294 0.614 rs78521938 chr6:28279823 G/A cg08851530 chr6:28072375 NA 1.54 6.89 0.53 2.51e-10 Parkinson's disease; TGCT cis rs28735056 0.875 rs62103176 chr18:77623611 G/C cg20368463 chr18:77673604 PQLC1 0.39 4.76 0.39 5.21e-6 Schizophrenia; TGCT cis rs1903068 1.000 rs9312658 chr4:56005526 C/A cg09978860 chr4:56023921 NA 0.59 6.73 0.52 5.59e-10 Endometriosis; TGCT cis rs7826238 0.539 rs2945891 chr8:8155475 C/T cg06636001 chr8:8085503 FLJ10661 0.78 7.25 0.55 3.94e-11 Systolic blood pressure; TGCT cis rs514406 0.861 rs6588443 chr1:53250650 G/A cg25767906 chr1:53392781 SCP2 0.48 5.55 0.45 1.62e-7 Monocyte count; TGCT cis rs6545883 0.831 rs1186704 chr2:61672991 A/G cg15711740 chr2:61764176 XPO1 -0.56 -5.06 -0.41 1.5e-6 Tuberculosis; TGCT cis rs7104764 1.000 rs7483951 chr11:231758 G/A cg18336825 chr11:236787 PSMD13;SIRT3 1.07 11.15 0.71 2.05e-20 Menarche (age at onset); TGCT cis rs736408 0.648 rs3774354 chr3:52817675 G/A cg11041457 chr3:52719354 GNL3;PBRM1 0.57 5.32 0.43 4.73e-7 Bipolar disorder; TGCT cis rs4595586 0.545 rs7952765 chr12:39375325 C/G cg10518543 chr12:38710700 ALG10B 0.54 4.44 0.37 1.93e-5 Morning vs. evening chronotype; TGCT cis rs860295 0.557 rs915181 chr1:155914772 C/T cg13795986 chr1:155880507 RIT1 0.36 4.45 0.37 1.87e-5 Body mass index; TGCT cis rs7727544 0.678 rs7735891 chr5:131597005 C/T cg21474247 chr5:131268130 NA 0.3 4.44 0.37 1.94e-5 Blood metabolite levels; TGCT cis rs2456568 0.695 rs908748 chr11:93690148 G/A cg26875233 chr11:93583750 C11orf90 0.39 4.76 0.39 5.28e-6 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs2832191 0.791 rs2832186 chr21:30484151 A/C cg08807101 chr21:30365312 RNF160 -0.63 -6.01 -0.47 1.96e-8 Dental caries; TGCT cis rs10504229 0.683 rs56741275 chr8:58136108 C/G cg08280861 chr8:58055591 NA 0.39 4.63 0.38 9.06e-6 Developmental language disorder (linguistic errors); TGCT cis rs9796 0.576 rs13329511 chr15:41299121 T/C cg26219294 chr15:41245916 CHAC1 0.38 4.64 0.38 8.63e-6 Menopause (age at onset); TGCT cis rs4862307 0.808 rs6817858 chr4:185000321 G/A cg06737308 chr4:185021514 ENPP6 -0.37 -5.39 -0.44 3.41e-7 Serum dimethylarginine levels (asymmetric/symetric ratio); TGCT cis rs1580019 0.563 rs4723169 chr7:32567577 G/A cg07520158 chr7:32535189 LSM5;AVL9 0.57 4.9 0.4 2.93e-6 Cognitive ability; TGCT cis rs6951245 1.000 rs75016635 chr7:1094121 G/A cg23708337 chr7:1209742 NA 0.64 5.94 0.47 2.63e-8 C-reactive protein levels or total cholesterol levels (pleiotropy); TGCT cis rs10984561 0.881 rs10491525 chr9:122256485 C/G cg14242995 chr9:122249943 NA 0.74 6.01 0.47 1.96e-8 Pulmonary function decline; TGCT cis rs36051895 0.695 rs10120763 chr9:5002911 C/G cg02405213 chr9:5042618 JAK2 -0.76 -10.04 -0.67 1e-17 Pediatric autoimmune diseases; TGCT cis rs968567 0.539 rs174560 chr11:61581764 T/C cg01500311 chr11:61656094 FADS3 -0.29 -4.9 -0.4 2.92e-6 Blood metabolite levels;Rheumatoid arthritis;Vitiligo;Glycerophospholipid levels; TGCT cis rs2204008 0.774 rs11495520 chr12:38060605 T/G cg26384229 chr12:38710491 ALG10B 0.86 7.77 0.57 2.55e-12 Bladder cancer; TGCT cis rs4455778 0.538 rs7779474 chr7:49107537 A/G cg26309511 chr7:48887640 NA 0.48 5.96 0.47 2.39e-8 Lung cancer in never smokers; TGCT cis rs9486719 0.857 rs4486027 chr6:96911886 T/C cg06623918 chr6:96969491 KIAA0776 -1.08 -10.73 -0.69 2.15e-19 Migraine;Coronary artery disease; TGCT cis rs10256972 0.552 rs2960830 chr7:1200641 T/C cg18765753 chr7:1198926 ZFAND2A -0.53 -6.72 -0.52 6.02e-10 Longevity;Endometriosis; TGCT cis rs34065801 0.632 rs1104539 chr13:36515298 C/T cg03563146 chr13:37393157 RFXAP -0.48 -4.47 -0.37 1.75e-5 Breast size; TGCT cis rs2859741 0.967 rs575939 chr1:37513854 T/C cg09363841 chr1:37513479 NA -0.2 -4.64 -0.38 8.86e-6 Forced expiratory volume in 1 second (environmental tobacco smoke interaction); TGCT cis rs7119038 0.818 rs17122453 chr11:118683564 G/A cg19308663 chr11:118741387 NA 0.28 5.69 0.45 8.68e-8 Sjögren's syndrome; TGCT cis rs6912958 0.559 rs2985039 chr6:88041757 A/G cg08069147 chr6:88032118 GJB7;C6orf162 0.7 7.16 0.54 6.1e-11 Monocyte percentage of white cells; TGCT trans rs7726839 0.540 rs4957081 chr5:646418 G/C cg11887960 chr12:57824829 NA 1.12 9.19 0.64 1.16e-15 Obesity-related traits; TGCT cis rs3812831 0.599 rs428637 chr13:114927139 T/G cg06611532 chr13:114900021 NA 0.34 6.19 0.49 8.15e-9 Schizophrenia; TGCT trans rs6089829 0.962 rs6089824 chr20:61659207 A/G cg17470723 chr8:74884337 TCEB1 0.72 6.94 0.53 1.91e-10 Prostate cancer (SNP x SNP interaction); TGCT cis rs9902453 0.765 rs2169810 chr17:28167941 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.82 7.62 0.56 5.56e-12 Coffee consumption (cups per day); TGCT cis rs617219 0.671 rs2591392 chr5:78546293 G/A cg09550809 chr5:78407562 BHMT 0.39 5.37 0.43 3.71e-7 Betaine levels in individuals undergoing cardiac evaluation; TGCT cis rs1799949 1.000 rs35668327 chr17:41273095 G/A cg10047753 chr17:41438598 NA 0.92 8.88 0.62 6.26e-15 Menopause (age at onset); TGCT cis rs2197308 0.728 rs7304305 chr12:37932990 T/C cg26384229 chr12:38710491 ALG10B -0.7 -6.15 -0.48 9.71e-9 Morning vs. evening chronotype; TGCT cis rs514406 0.893 rs1242326 chr1:53399104 C/A cg08736216 chr1:53307985 ZYG11A -0.29 -6.09 -0.48 1.32e-8 Monocyte count; TGCT cis rs7267979 1.000 rs453329 chr20:25440593 G/A cg14121845 chr20:25566513 NINL 0.5 5.44 0.44 2.79e-7 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9814567 1.000 rs9828815 chr3:134265749 C/T cg06109529 chr3:134205091 CEP63;ANAPC13 -0.95 -9.55 -0.65 1.56e-16 Neurocognitive impairment in HIV-1 infection (dichotomous); TGCT cis rs13064411 0.696 rs7610638 chr3:113139656 A/G cg18753928 chr3:113234510 CCDC52 -0.69 -5.23 -0.43 6.83e-7 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs17253792 0.749 rs79713967 chr14:56124186 T/C cg01858014 chr14:56050164 KTN1 -0.35 -4.65 -0.39 8.23e-6 Putamen volume; TGCT cis rs7178572 0.568 rs11857294 chr15:77596725 C/T cg15453836 chr15:77711506 NA -0.42 -4.79 -0.4 4.68e-6 Type 2 diabetes; TGCT cis rs42648 0.596 rs194520 chr7:89854446 T/G cg25739043 chr7:89950458 NA -0.51 -4.85 -0.4 3.65e-6 Homocysteine levels; TGCT cis rs6495122 0.699 rs1378940 chr15:75083494 C/A cg10253484 chr15:75165896 SCAMP2 -0.68 -5.98 -0.47 2.2e-8 Caffeine consumption;Diastolic blood pressure;Coffee consumption; TGCT cis rs1215050 0.818 rs6532703 chr4:98777486 A/T cg17366294 chr4:99064904 C4orf37 0.48 4.83 0.4 3.94e-6 Waist-to-hip ratio adjusted for body mass index; TGCT cis rs9393692 0.905 rs7769028 chr6:26267568 C/T cg13736514 chr6:26305472 NA -0.39 -5.6 -0.45 1.31e-7 Educational attainment; TGCT cis rs9487051 0.872 rs1111864 chr6:109611138 A/G cg01475377 chr6:109611718 NA -0.29 -4.56 -0.38 1.23e-5 Reticulocyte fraction of red cells; TGCT cis rs752010 0.715 rs4083592 chr1:42099522 A/G cg06885757 chr1:42089581 HIVEP3 0.28 4.91 0.4 2.79e-6 Lupus nephritis in systemic lupus erythematosus; TGCT cis rs9291683 0.618 rs13137343 chr4:10043028 C/A cg11266682 chr4:10021025 SLC2A9 0.64 8.75 0.62 1.29e-14 Bone mineral density; TGCT cis rs4563143 0.675 rs73025085 chr19:29247018 C/A cg04546413 chr19:29218101 NA 0.84 6.82 0.52 3.52e-10 Methadone dose in opioid dependence; TGCT cis rs459571 0.804 rs448918 chr9:136885979 G/A cg14405625 chr9:136855902 VAV2 -0.3 -4.44 -0.37 1.97e-5 Platelet distribution width; TGCT cis rs644799 1.000 rs566204 chr11:95580926 G/A cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.11 0.59 4.26e-13 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs1008375 0.898 rs4698623 chr4:17594702 T/C cg16339924 chr4:17578868 LAP3 0.8 6.52 0.51 1.61e-9 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs838147 0.507 rs692854 chr19:49209464 C/A cg04599840 chr19:48886497 KDELR1 0.21 4.44 0.37 1.97e-5 Dietary macronutrient intake; TGCT cis rs1570884 0.516 rs9316463 chr13:50176844 G/A cg08779649 chr13:50194554 NA 0.37 5.84 0.46 4.24e-8 Sum basophil neutrophil counts;Sum neutrophil eosinophil counts;Neutrophil count;Myeloid white cell count;Granulocyte count; TGCT cis rs12048904 0.964 rs17123467 chr1:101331760 G/A cg15686842 chr1:101360669 SLC30A7;EXTL2 0.5 4.54 0.38 1.31e-5 Multiple sclerosis; TGCT cis rs7618915 0.570 rs11130312 chr3:52675055 A/C cg07507251 chr3:52567010 NT5DC2 0.47 6.7 0.52 6.47e-10 Bipolar disorder; TGCT cis rs950776 0.616 rs56276142 chr15:78889795 T/C cg06917634 chr15:78832804 PSMA4 0.65 5.3 0.43 5.01e-7 Sudden cardiac arrest; TGCT cis rs4268898 0.722 rs7563958 chr2:24422381 C/A cg02683114 chr2:24398427 C2orf84 0.19 4.62 0.38 9.4e-6 Asthma; TGCT cis rs7975161 0.938 rs10400561 chr12:104640920 A/G cg25273343 chr12:104657179 TXNRD1 -0.33 -5.07 -0.41 1.44e-6 Toenail selenium levels; TGCT cis rs4253772 0.591 rs6008595 chr22:46703860 A/T cg24881330 chr22:46731750 TRMU 1.04 5.41 0.44 3.12e-7 LDL cholesterol;Cholesterol, total; TGCT cis rs10779751 0.770 rs7553827 chr1:11222393 C/T cg08854313 chr1:11322531 MTOR 0.82 6.66 0.51 7.99e-10 Body mass index; TGCT cis rs4819852 0.958 rs756653 chr22:19976845 G/A cg07821417 chr22:19972146 ARVCF 0.19 4.79 0.4 4.7e-6 Pulse pressure; TGCT cis rs10088262 0.629 rs7828192 chr8:124804669 C/T cg02993010 chr8:124780839 FAM91A1 -0.63 -5.13 -0.42 1.08e-6 Pancreatic cancer; TGCT cis rs12477438 0.684 rs6756880 chr2:99676991 A/T cg26064155 chr2:99771622 LIPT1;TSGA10 -0.53 -4.62 -0.38 9.47e-6 Chronic sinus infection; TGCT cis rs6089829 0.851 rs10854168 chr20:61669550 A/G cg18188782 chr20:61659543 NA 0.44 4.88 0.4 3.17e-6 Prostate cancer (SNP x SNP interaction); TGCT cis rs9341808 0.727 rs9352809 chr6:80999316 C/T cg08355045 chr6:80787529 NA 0.26 4.55 0.38 1.28e-5 Sitting height ratio; TGCT cis rs433598 0.894 rs180149 chr16:20676969 G/A cg08248577 chr16:19727447 IQCK;C16orf88 -0.22 -5.29 -0.43 5.36e-7 Schizophrenia; TGCT trans rs10506458 1.000 rs17763435 chr12:63416511 A/G cg03429785 chr15:59498649 MYO1E;LDHAL6B 0.47 7.48 0.56 1.18e-11 Hemostatic factors and hematological phenotypes; TGCT cis rs7666738 0.546 rs9993299 chr4:98815976 G/A cg05340658 chr4:99064831 C4orf37 0.53 5.82 0.46 4.71e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs2228479 0.717 rs9282682 chr16:89805794 A/G cg27121462 chr16:89883253 FANCA 0.78 4.65 0.39 8.46e-6 Skin colour saturation; TGCT cis rs1008375 1.000 rs4642241 chr4:17617111 T/C cg18681998 chr4:17616180 MED28 0.99 11.48 0.72 3.18e-21 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs4499344 0.730 rs405858 chr19:33106621 A/G cg27413643 chr19:33165484 ANKRD27;RGS9BP -0.77 -8.08 -0.59 4.96e-13 Mean platelet volume; TGCT trans rs941408 1.000 rs1736177 chr19:2791624 C/T cg19676328 chr12:49525230 TUBA1B -0.76 -7.72 -0.57 3.34e-12 Total cholesterol levels; TGCT cis rs6866344 0.570 rs59259518 chr5:178142628 C/T cg10224037 chr5:178157518 ZNF354A 0.95 8.98 0.63 3.58e-15 Neutrophil percentage of white cells; TGCT cis rs6988636 1.000 rs11992152 chr8:124189455 T/A cg27053337 chr8:124217698 FAM83A 0.58 4.81 0.4 4.3e-6 Urinary uromodulin levels; TGCT cis rs2243480 1.000 rs34702770 chr7:65344823 T/C cg20637647 chr7:64974828 NA 0.88 5.0 0.41 1.93e-6 Diabetic kidney disease; TGCT cis rs9660180 0.967 rs11260623 chr1:1781456 G/T cg13866156 chr1:1669148 SLC35E2 -0.21 -5.0 -0.41 1.88e-6 Body mass index; TGCT cis rs9549367 0.762 rs9549694 chr13:113870510 G/A cg00898013 chr13:113819073 PROZ -0.43 -5.52 -0.44 1.87e-7 Platelet distribution width; TGCT cis rs8072100 0.967 rs11656855 chr17:45714655 C/T cg08085267 chr17:45401833 C17orf57 0.43 4.63 0.38 9.04e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs644799 0.965 rs3016295 chr11:95554311 A/G cg25622487 chr11:95524042 FAM76B;CEP57 0.83 8.74 0.62 1.39e-14 Intelligence (multi-trait analysis);Cognitive ability (multi-trait analysis); TGCT cis rs7666738 0.753 rs11097594 chr4:98944486 A/G cg18180107 chr4:99064573 C4orf37 0.57 5.16 0.42 9.32e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs1552244 0.882 rs13089863 chr3:10032259 G/T cg00149659 chr3:10157352 C3orf10 -0.73 -4.84 -0.4 3.86e-6 Alzheimer's disease; TGCT cis rs2739330 0.760 rs5751760 chr22:24243573 G/A cg01238044 chr22:24384105 GSTT1 -0.49 -4.61 -0.38 9.74e-6 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs9926296 0.572 rs8047581 chr16:89884502 C/T cg08627397 chr16:89984028 MC1R -0.32 -5.25 -0.43 6.31e-7 Vitiligo; TGCT cis rs10193935 0.901 rs10170082 chr2:42623452 T/C cg27598129 chr2:42591480 NA -0.37 -5.23 -0.42 7.1e-7 Colonoscopy-negative controls vs population controls; TGCT cis rs9894429 0.966 rs6565605 chr17:79589359 C/T cg18240062 chr17:79603768 NPLOC4 0.67 6.85 0.52 3.11e-10 Eye color traits; TGCT cis rs752092 1.000 rs752092 chr15:101781934 C/T cg19997662 chr15:101784653 CHSY1 0.32 5.96 0.47 2.4e-8 Corneal structure; TGCT cis rs7726839 0.540 rs56325086 chr5:640728 G/A cg16624210 chr5:671434 TPPP 0.4 4.59 0.38 1.07e-5 Obesity-related traits; TGCT cis rs13118159 0.550 rs4974614 chr4:1373489 A/G cg05025164 chr4:1340916 KIAA1530 0.75 6.21 0.49 7.3e-9 Longevity; TGCT cis rs9902453 0.845 rs12601963 chr17:28246358 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.81 7.28 0.55 3.32e-11 Coffee consumption (cups per day); TGCT cis rs67311347 0.955 rs4973999 chr3:40460383 G/A cg13683864 chr3:40499215 RPL14 -1.04 -10.79 -0.7 1.54e-19 Renal cell carcinoma; TGCT cis rs514406 0.547 rs377808 chr1:53190359 T/G cg01802117 chr1:53393560 SCP2 -0.4 -4.61 -0.38 9.76e-6 Monocyte count; TGCT cis rs17718580 0.826 rs72679544 chr14:51031469 C/A cg04730355 chr14:51134070 SAV1 1.0 5.61 0.45 1.24e-7 Cognitive performance; TGCT cis rs6752107 0.500 rs11893210 chr2:234204672 A/G cg25333460 chr2:234370070 DGKD 0.2 4.44 0.37 2e-5 Crohn's disease;Inflammatory bowel disease; TGCT trans rs1814175 0.935 rs7479914 chr11:49661351 T/C cg03929089 chr4:120376271 NA -0.65 -7.42 -0.55 1.59e-11 Height; TGCT cis rs7666738 0.822 rs9992360 chr4:98937123 T/C cg05340658 chr4:99064831 C4orf37 0.52 5.91 0.47 3.12e-8 Colonoscopy-negative controls vs population controls; TGCT cis rs1008375 1.000 rs2872958 chr4:17665032 A/G cg10189774 chr4:17578691 LAP3 0.54 5.08 0.41 1.38e-6 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs807669 0.548 rs885978 chr22:19198226 A/G cg02655711 chr22:19163373 SLC25A1 0.3 5.9 0.47 3.22e-8 Metabolite levels; TGCT cis rs6684514 1.000 rs12142808 chr1:156230546 G/A cg16558208 chr1:156270281 VHLL 0.46 8.56 0.61 3.68e-14 Mean corpuscular hemoglobin concentration;Glycated hemoglobin levels; TGCT cis rs1577917 0.958 rs2875456 chr6:86602284 G/A cg17490806 chr6:86388072 SNHG5;SNORD50B;SNORD50A -0.64 -5.19 -0.42 8.51e-7 Response to antipsychotic treatment; TGCT cis rs2739330 0.731 rs4822450 chr22:24242887 C/T cg04234412 chr22:24373322 LOC391322 -0.94 -11.78 -0.73 5.91e-22 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs79349575 0.715 rs62075844 chr17:47002389 G/A cg07967210 chr17:47022446 SNF8 0.44 6.12 0.48 1.13e-8 Type 2 diabetes; TGCT cis rs2243480 1.000 rs1553174 chr7:65731194 T/C cg18252515 chr7:66147081 NA 1.25 7.75 0.57 2.92e-12 Diabetic kidney disease; TGCT cis rs1865760 0.516 rs9379818 chr6:26023206 G/T cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.78 7.56 0.56 7.89e-12 Height; TGCT cis rs981844 0.796 rs11099904 chr4:154681861 A/G cg14289246 chr4:154710475 SFRP2 0.87 7.49 0.56 1.1e-11 Response to statins (LDL cholesterol change); TGCT cis rs2456568 0.802 rs8181578 chr11:93637442 G/A cg26875233 chr11:93583750 C11orf90 -0.48 -6.47 -0.5 2.09e-9 Response to serotonin reuptake inhibitors in major depressive disorder; TGCT cis rs7572733 0.576 rs1865586 chr2:198758868 C/T cg00792783 chr2:198669748 PLCL1 -0.54 -4.93 -0.4 2.57e-6 Dermatomyositis; TGCT cis rs919433 0.679 rs13000656 chr2:198522126 T/C cg00792783 chr2:198669748 PLCL1 -0.54 -4.78 -0.39 4.82e-6 Intracranial, abdominal aortic or thoracic aortic aneurysm (pleiotropy); TGCT cis rs2549003 1.000 rs17848418 chr5:131821188 C/T cg00255919 chr5:131827918 IRF1 0.2 4.7 0.39 6.92e-6 Asthma (sex interaction); TGCT cis rs2836974 0.897 rs14194 chr21:40549466 T/C cg11890956 chr21:40555474 PSMG1 1.14 12.22 0.74 4.93e-23 Cognitive function; TGCT cis rs9326248 0.954 rs10790177 chr11:117048417 A/G cg16524733 chr11:117070046 TAGLN 0.31 4.49 0.37 1.62e-5 Blood protein levels; TGCT cis rs12216125 0.537 rs12207059 chr6:25922385 C/T cg17691542 chr6:26056736 HIST1H1C 0.89 6.28 0.49 5.3e-9 Iron status biomarkers; TGCT cis rs7666738 0.830 rs17558151 chr4:99048699 T/C cg18180107 chr4:99064573 C4orf37 0.56 5.08 0.41 1.37e-6 Colonoscopy-negative controls vs population controls; TGCT cis rs909674 0.514 rs7423 chr22:39781429 C/T cg05872129 chr22:39784769 NA -0.96 -11.04 -0.7 3.71e-20 IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis);IgG glycosylation;IgG digalactosylation phenotypes (multivariate analysis);IgG sialylation phenotypes (multivariate analysis);IgG monogalactosylation phenotypes (multivariate analysis);IgG fucosylation phenotypes (multivariate analysis);IgG N-glycosylation phenotypes (multivariate analysis);IgG disialylation phenotypes (multivariate analysis);IgG galactosylation phenotypes (multivariate analysis);Post bronchodilator FEV1; TGCT trans rs6089829 0.925 rs6122087 chr20:61664553 T/C cg23505145 chr19:12996616 KLF1 0.78 8.12 0.59 4.03e-13 Prostate cancer (SNP x SNP interaction); TGCT cis rs3749237 0.595 rs11130192 chr3:49467206 C/G cg07636037 chr3:49044803 WDR6 0.63 6.07 0.48 1.47e-8 Resting heart rate; TGCT cis rs7267979 0.816 rs8115257 chr20:25207931 A/G cg14121845 chr20:25566513 NINL 0.46 4.67 0.39 7.74e-6 Liver enzyme levels (alkaline phosphatase); TGCT cis rs9868809 0.505 rs13434258 chr3:48738491 T/C cg00383909 chr3:49044727 WDR6 1.06 6.28 0.49 5.26e-9 Ulcerative colitis;Crohn's disease;Inflammatory bowel disease; TGCT cis rs4689388 0.890 rs4501291 chr4:6298582 C/T cg25554036 chr4:6271136 WFS1 0.56 7.87 0.58 1.48e-12 Type 2 diabetes and other traits;Type 2 diabetes; TGCT cis rs9399135 0.933 rs9389262 chr6:135376409 G/T cg24558204 chr6:135376177 HBS1L 0.48 4.76 0.39 5.21e-6 Red blood cell count; TGCT cis rs6977660 0.714 rs17141882 chr7:19790217 C/T cg05791153 chr7:19748676 TWISTNB 0.88 5.05 0.41 1.52e-6 Thyroid stimulating hormone; TGCT cis rs916888 0.773 rs199448 chr17:44809001 A/G cg05721485 chr17:44071124 MAPT 0.24 4.46 0.37 1.84e-5 Post bronchodilator FEV1;Cognitive function;Intelligence (multi-trait analysis);Multiple system atrophy; TGCT cis rs7208859 0.623 rs55938328 chr17:29117010 T/C cg13385521 chr17:29058706 SUZ12P 0.8 4.85 0.4 3.58e-6 Mean corpuscular hemoglobin;Mean corpuscular volume; TGCT cis rs77741769 0.534 rs58918988 chr12:121332953 G/A cg02419362 chr12:121203948 SPPL3 0.19 4.5 0.37 1.56e-5 Mean corpuscular volume; TGCT cis rs7104764 0.917 rs3825075 chr11:217140 C/T cg18336825 chr11:236787 PSMD13;SIRT3 -0.73 -7.03 -0.53 1.2e-10 Menarche (age at onset); TGCT cis rs8017423 0.967 rs7158180 chr14:90729117 C/T cg04374321 chr14:90722782 PSMC1 0.78 7.86 0.58 1.59e-12 Mortality in heart failure; TGCT cis rs6570726 0.791 rs370112 chr6:145859853 T/G cg05347473 chr6:146136440 FBXO30 0.54 5.15 0.42 1.01e-6 Lobe attachment (rater-scored or self-reported); TGCT cis rs9916302 0.851 rs11870631 chr17:37645129 C/T cg07936489 chr17:37558343 FBXL20 -0.62 -4.91 -0.4 2.85e-6 Glomerular filtration rate (creatinine); TGCT cis rs7829975 0.582 rs6983150 chr8:8792426 A/G cg00184457 chr8:8946301 NA -0.23 -4.44 -0.37 2e-5 Mood instability; TGCT cis rs903263 0.965 rs6699600 chr1:84592169 C/G cg09664975 chr1:84543551 PRKACB 0.49 4.55 0.38 1.26e-5 Breast cancer (male); TGCT cis rs2797160 1.000 rs1418951 chr6:125996185 A/G cg05901451 chr6:126070800 HEY2 -0.74 -6.49 -0.5 1.84e-9 Endometrial cancer; TGCT cis rs7584330 0.666 rs72620818 chr2:238354652 G/A cg14458575 chr2:238380390 NA 0.56 8.26 0.6 1.84e-13 Prostate cancer; TGCT cis rs910316 0.967 rs4384542 chr14:75658013 A/C cg11812906 chr14:75593930 NEK9 -0.72 -6.87 -0.53 2.72e-10 Height; TGCT cis rs2760061 0.819 rs708112 chr1:228192452 G/A cg18477163 chr1:228402036 OBSCN 0.34 7.16 0.54 6.26e-11 Diastolic blood pressure; TGCT cis rs9611565 0.918 rs6002351 chr22:41757223 C/T cg06481639 chr22:41940642 POLR3H -0.58 -5.01 -0.41 1.81e-6 Vitiligo; TGCT cis rs79349575 0.783 rs56046215 chr17:47008757 A/T cg07967210 chr17:47022446 SNF8 0.44 6.13 0.48 1.1e-8 Type 2 diabetes; TGCT cis rs9902453 0.780 rs62068621 chr17:28170382 A/G cg26525008 chr17:28256777 EFCAB5;SSH2 0.77 7.17 0.54 5.79e-11 Coffee consumption (cups per day); TGCT cis rs6933660 0.666 rs9371516 chr6:151739642 G/A cg14416726 chr6:151773293 C6orf211;RMND1 -0.86 -9.43 -0.65 3.05e-16 Menarche (age at onset); TGCT cis rs4713118 0.615 rs57252182 chr6:27720249 C/A cg10876282 chr6:28092338 ZSCAN16 0.5 5.09 0.42 1.29e-6 Parkinson's disease; TGCT cis rs950169 0.544 rs62021193 chr15:85170583 C/G cg17173187 chr15:85201210 NMB 0.6 6.81 0.52 3.78e-10 Schizophrenia; TGCT cis rs12220238 1.000 rs4320897 chr10:76017732 C/G cg19889307 chr10:75911429 ADK;AP3M1 0.93 7.36 0.55 2.26e-11 Soluble interleukin-2 receptor subunit alpha; TGCT cis rs72843506 0.586 rs73980762 chr17:19869426 T/C cg18979559 chr17:20280153 CCDC144C -0.59 -4.5 -0.37 1.53e-5 Schizophrenia; TGCT cis rs12464483 0.524 rs2593470 chr2:30887402 G/T cg12454169 chr2:30669597 LCLAT1 0.45 4.91 0.4 2.75e-6 Pre-treatment pain in head and neck squamous cell carcinoma; TGCT cis rs13064411 0.542 rs1463643 chr3:113215447 A/G cg18753928 chr3:113234510 CCDC52 -0.54 -4.58 -0.38 1.12e-5 Response to simvastatin treatment (PCSK9 protein level change); TGCT cis rs514406 0.722 rs7552139 chr1:53387379 G/C cg08736216 chr1:53307985 ZYG11A -0.28 -5.73 -0.46 7.33e-8 Monocyte count; TGCT cis rs2688482 0.557 rs3103952 chr3:195522690 T/C cg13752114 chr3:195489708 MUC4 0.35 4.98 0.41 2.05e-6 Lung disease severity in cystic fibrosis; TGCT cis rs11677370 0.533 rs12711971 chr2:3820821 G/C cg17052675 chr2:3827356 NA -0.45 -7.95 -0.58 9.92e-13 Type 2 diabetes; TGCT cis rs826838 0.872 rs826878 chr12:39088837 A/T cg26384229 chr12:38710491 ALG10B -0.82 -7.79 -0.57 2.28e-12 Heart rate; TGCT cis rs12188164 1.000 rs56104584 chr5:437542 T/C cg17553881 chr5:443987 EXOC3;C5orf55 -0.4 -4.76 -0.39 5.33e-6 Cystic fibrosis severity; TGCT cis rs4862750 0.794 rs1030382 chr4:187903782 T/G cg10295955 chr4:187884368 NA -0.98 -15.43 -0.81 1.25e-30 Lobe attachment (rater-scored or self-reported); TGCT cis rs7017914 0.905 rs12542300 chr8:71951395 C/G cg23757474 chr8:71581111 LACTB2;XKR9 0.54 4.99 0.41 2e-6 Bone mineral density; TGCT cis rs11997175 0.574 rs10954931 chr8:33631066 A/T ch.8.33884649F chr8:33765107 NA 0.28 4.45 0.37 1.87e-5 Body mass index; TGCT cis rs2742417 1.000 rs2742386 chr3:45756310 A/C cg04837898 chr3:45731254 SACM1L -0.52 -5.28 -0.43 5.58e-7 Response to anti-depressant treatment in major depressive disorder; TGCT cis rs9348729 1 rs9348729 chr6:26664268 T/C cg06675483 chr6:26987649 LOC100270746;C6orf41 -0.5 -4.72 -0.39 6.15e-6 Intelligence (multi-trait analysis); TGCT cis rs1348850 0.632 rs1405718 chr2:178499809 C/T cg22681709 chr2:178499509 PDE11A -0.52 -6.73 -0.52 5.53e-10 Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL); TGCT cis rs68170813 0.559 rs76307631 chr7:107058018 A/G cg02696742 chr7:106810147 HBP1 -0.68 -5.44 -0.44 2.69e-7 Coronary artery disease; TGCT cis rs28595532 0.920 rs114410095 chr4:119731110 G/A cg21605333 chr4:119757512 SEC24D 1.66 8.33 0.6 1.28e-13 Cannabis dependence symptom count; TGCT cis rs28735056 0.584 rs35614280 chr18:77636679 C/G cg20368463 chr18:77673604 PQLC1 0.46 5.36 0.43 3.88e-7 Schizophrenia; TGCT cis rs1801251 0.963 rs13011298 chr2:233612996 A/G cg08000102 chr2:233561755 GIGYF2 0.64 6.52 0.51 1.58e-9 Coronary artery disease; TGCT cis rs6714710 0.603 rs17489984 chr2:98421364 A/G cg26665480 chr2:98280029 ACTR1B 0.66 6.27 0.49 5.45e-9 Posterior cortical atrophy and Alzheimer's disease; TGCT cis rs2933343 0.700 rs1680779 chr3:128614770 G/A cg11901034 chr3:128598214 ACAD9 -0.63 -5.72 -0.46 7.48e-8 IgG glycosylation; TGCT cis rs6429082 0.633 rs1416473 chr1:235563259 C/T cg26050004 chr1:235667680 B3GALNT2 -0.51 -4.44 -0.37 1.93e-5 Adiposity; TGCT cis rs6831352 0.879 rs36034266 chr4:100061388 T/C cg12011299 chr4:100065546 ADH4 -0.41 -4.97 -0.41 2.21e-6 Alcohol dependence; TGCT cis rs7714584 1.000 rs7714584 chr5:150270420 A/G cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs1865760 0.963 rs1540273 chr6:25924158 T/C cg18576210 chr6:26033786 HIST1H3B;HIST1H2AB 0.65 6.21 0.49 7.42e-9 Height; TGCT cis rs1062177 0.756 rs2964588 chr5:151118386 C/T cg12924095 chr5:151150029 G3BP1 -0.34 -4.97 -0.41 2.17e-6 Preschool internalizing problems; TGCT cis rs8031584 0.706 rs798084 chr15:31126935 C/T cg08109568 chr15:31115862 NA -0.4 -5.35 -0.43 4.1e-7 Huntington's disease progression; TGCT cis rs7829975 0.511 rs2976902 chr8:8341105 T/G cg15556689 chr8:8085844 FLJ10661 0.63 6.09 0.48 1.3e-8 Mood instability; TGCT cis rs2439831 1.000 rs2467740 chr15:43746792 C/T cg27015174 chr15:43622946 ADAL;LCMT2 0.8 5.7 0.46 8.33e-8 Lung cancer in ever smokers; TGCT cis rs6089829 0.962 rs9679865 chr20:61666132 C/G cg03213289 chr20:61660250 NA 0.7 10.11 0.67 6.94e-18 Prostate cancer (SNP x SNP interaction); TGCT cis rs9650657 0.524 rs10088408 chr8:10817197 C/T cg21775007 chr8:11205619 TDH -0.53 -4.96 -0.41 2.25e-6 Neuroticism; TGCT cis rs74054849 0.850 rs78132144 chr1:15939883 A/T cg05660106 chr1:15850417 CASP9 0.86 4.47 0.37 1.71e-5 Alcoholic chronic pancreatitis; TGCT cis rs3087591 0.639 rs7223589 chr17:29728284 T/C cg24425628 chr17:29625626 OMG;NF1 0.36 5.06 0.41 1.49e-6 Hip circumference; TGCT cis rs13108904 0.967 rs1732107 chr4:1276758 G/A cg13395646 chr4:1353034 KIAA1530 0.39 4.78 0.39 4.96e-6 Obesity-related traits; TGCT cis rs694739 0.595 rs11606015 chr11:64136877 C/G cg02228329 chr11:64053129 BAD;GPR137 0.69 6.78 0.52 4.25e-10 Alopecia areata;Crohn's disease;Psoriasis vulgaris; TGCT cis rs9486719 0.857 rs4839833 chr6:96882069 T/C cg06623918 chr6:96969491 KIAA0776 1.03 10.94 0.7 6.47e-20 Migraine;Coronary artery disease; TGCT cis rs637571 0.522 rs528736 chr11:65705108 A/G cg04055107 chr11:65626734 MUS81;CFL1 0.46 4.65 0.39 8.2e-6 Eosinophil percentage of white cells; TGCT cis rs2739330 0.760 rs5751761 chr22:24243736 A/G cg12419862 chr22:24373484 LOC391322 0.85 10.0 0.67 1.26e-17 Liver enzyme levels (gamma-glutamyl transferase); TGCT cis rs12210905 0.688 rs12199806 chr6:27435943 A/C cg08851530 chr6:28072375 NA 1.34 6.29 0.49 5.02e-9 Hip circumference adjusted for BMI; TGCT cis rs4733781 0.965 rs1469288 chr8:131226652 G/A cg16277922 chr8:131349729 ASAP1 0.45 5.54 0.45 1.7e-7 Tuberculosis; TGCT cis rs2718812 0.792 rs3772680 chr3:133371807 A/G cg16414030 chr3:133502952 NA -0.4 -5.19 -0.42 8.27e-7 Iron status biomarkers; TGCT cis rs2243480 1.000 rs6964530 chr7:65718851 G/C cg07424592 chr7:64974309 NA -1.3 -7.55 -0.56 8.08e-12 Diabetic kidney disease; TGCT cis rs4664308 1.000 rs2175416 chr2:160904021 G/A cg03641300 chr2:160917029 PLA2R1 -0.26 -6.53 -0.51 1.49e-9 Idiopathic membranous nephropathy; TGCT cis rs4766566 0.609 rs933305 chr12:111738287 G/A cg10833066 chr12:111807467 FAM109A 0.4 6.35 0.5 3.68e-9 Atrial fibrillation;Renal underexcretion gout;Gout;Renal overload gout; TGCT cis rs7843479 0.601 rs12056476 chr8:21854188 T/A cg17168535 chr8:21777572 XPO7 0.8 8.02 0.58 6.73e-13 Mean corpuscular volume; TGCT cis rs4975709 0.544 rs4975748 chr5:1866025 G/A cg12288994 chr5:1860383 NA 0.26 5.1 0.42 1.22e-6 Cardiovascular disease risk factors; TGCT cis rs7714584 1.000 rs1820682 chr5:150262142 T/C cg22134413 chr5:150180641 NA 0.78 6.12 0.48 1.16e-8 Crohn's disease; TGCT cis rs4742903 0.935 rs10820602 chr9:106861282 C/T cg21169611 chr9:106856078 SMC2 0.49 4.6 0.38 1.03e-5 High-grade serous ovarian cancer;Breast cancer; TGCT cis rs1218582 0.772 rs4845689 chr1:154885524 A/G cg06418219 chr1:154948305 SHC1;CKS1B -0.69 -7.06 -0.54 1.07e-10 Prostate cancer; TGCT cis rs9291683 0.588 rs3756238 chr4:10013202 C/T cg00071950 chr4:10020882 SLC2A9 0.76 10.38 0.68 1.55e-18 Bone mineral density; TGCT cis rs5744897 0.655 rs35131280 chr12:133275974 A/G cg17341477 chr12:133246679 POLE 0.43 5.45 0.44 2.65e-7 Urate levels in overweight individuals; TGCT cis rs2404602 0.608 rs12439484 chr15:76602937 A/C cg26408565 chr15:76604113 ETFA -0.47 -6.63 -0.51 9.38e-10 Blood metabolite levels; TGCT cis rs8072100 1.000 rs4794016 chr17:45725931 T/A cg08085267 chr17:45401833 C17orf57 0.47 5.12 0.42 1.14e-6 Very long-chain saturated fatty acid levels (fatty acid 20:0); TGCT cis rs782590 0.556 rs782579 chr2:55917604 A/G cg03859395 chr2:55845619 SMEK2 0.66 6.77 0.52 4.51e-10 Metabolic syndrome; TGCT cis rs17376456 0.569 rs11135394 chr5:93187135 C/T cg09848695 chr5:92956644 FAM172A;MIR2277 -0.56 -4.76 -0.39 5.3e-6 Diabetic retinopathy; TGCT cis rs910316 0.789 rs175457 chr14:75584507 C/T cg11812906 chr14:75593930 NEK9 -0.64 -5.86 -0.47 3.9e-8 Height; TGCT cis rs9921338 0.923 rs4563054 chr16:11447546 T/G cg00044050 chr16:11439710 C16orf75 -0.79 -6.09 -0.48 1.28e-8 Vein graft stenosis in coronary artery bypass grafting; TGCT cis rs1372520 0.684 rs2619341 chr4:90741773 A/G cg20003494 chr4:90757398 SNCA -0.63 -5.06 -0.41 1.48e-6 Neuroticism; TGCT cis rs2235642 0.653 rs7197288 chr16:1654753 C/A cg10465839 chr16:1584050 IFT140;TMEM204 -0.28 -4.52 -0.38 1.44e-5 Coronary artery disease; TGCT cis rs1034435 0.755 rs713923 chr22:48891519 C/T cg05992904 chr22:48892994 FAM19A5 0.37 5.23 0.43 6.89e-7 Late-onset Alzheimer's disease; TGCT cis rs1008375 0.872 rs6831115 chr4:17640463 A/G cg18681998 chr4:17616180 MED28 1.0 11.93 0.73 2.54e-22 Parasitemia in Tripanosoma cruzi seropositivity; TGCT cis rs3785574 0.962 rs2665842 chr17:61878535 G/A cg11494091 chr17:61959527 GH2 0.42 7.28 0.55 3.36e-11 Height; TGCT cis rs56104184 0.830 rs17206679 chr19:49342237 C/G cg21252483 chr19:49399788 TULP2 -0.42 -5.58 -0.45 1.46e-7 Reticulocyte fraction of red cells;Reticulocyte count;High light scatter reticulocyte percentage of red cells;High light scatter reticulocyte count; TGCT cis rs13108904 0.901 rs12509700 chr4:1296321 A/G cg13395646 chr4:1353034 KIAA1530 -0.47 -5.77 -0.46 5.99e-8 Obesity-related traits; TGCT cis rs868036 0.609 rs2045960 chr15:68092079 G/A cg27219399 chr15:67835830 MAP2K5 0.34 4.49 0.37 1.59e-5 Restless legs syndrome; TGCT cis rs10504229 1.000 rs3814486 chr8:58191226 A/T cg20607798 chr8:58055168 NA 0.44 4.58 0.38 1.12e-5 Developmental language disorder (linguistic errors); TGCT cis rs651907 0.557 rs34947019 chr3:101532235 C/T cg11279151 chr3:101281821 RG9MTD1 -0.31 -6.5 -0.5 1.8e-9 Colorectal cancer; TGCT cis rs1862618 0.853 rs252904 chr5:56118733 A/T cg24549020 chr5:56110836 MAP3K1 0.69 5.91 0.47 3.09e-8 Initial pursuit acceleration; TGCT cis rs10779751 0.727 rs4845852 chr1:11233559 C/T cg08854313 chr1:11322531 MTOR 0.84 8.09 0.59 4.52e-13 Body mass index; TGCT cis rs10504229 1.000 rs114486414 chr8:58185103 G/A cg08219700 chr8:58056026 NA 0.3 4.59 0.38 1.08e-5 Developmental language disorder (linguistic errors); TGCT cis rs7267979 0.816 rs409853 chr20:25506067 T/C cg03522245 chr20:25566470 NINL 0.56 5.79 0.46 5.51e-8 Liver enzyme levels (alkaline phosphatase); TGCT cis rs12541335 0.639 rs13257108 chr8:22165043 T/C cg09517075 chr8:22133004 PIWIL2 0.25 4.99 0.41 1.95e-6 Hypertriglyceridemia; TGCT cis rs3806843 0.576 rs155359 chr5:140315425 G/T cg09824255 chr5:140014002 CD14 0.25 4.49 0.37 1.63e-5 Depressive symptoms (multi-trait analysis); TGCT cis rs514406 0.793 rs12081018 chr1:53217542 C/A cg24675658 chr1:53192096 ZYG11B 0.76 8.75 0.62 1.3e-14 Monocyte count; TGCT cis rs7044106 0.791 rs10760116 chr9:123494681 C/T cg14255062 chr9:123606675 PSMD5;LOC253039 0.2 4.77 0.39 5.05e-6 Hip circumference adjusted for BMI; TGCT cis rs1799949 0.894 rs8176160 chr17:41241503 T/C cg10047753 chr17:41438598 NA 0.95 9.5 0.65 2.09e-16 Menopause (age at onset); TGCT cis rs7819412 0.594 rs60921132 chr8:10964969 T/A cg03192020 chr8:11204681 TDH -0.57 -5.43 -0.44 2.81e-7 Triglycerides; TGCT cis rs10504229 0.906 rs56130194 chr8:58197061 C/A cg21724239 chr8:58056113 NA 0.38 4.72 0.39 6.3e-6 Developmental language disorder (linguistic errors); TGCT cis rs2708977 0.965 rs2314109 chr2:97243532 A/G cg01950434 chr2:97203154 ARID5A -0.64 -5.85 -0.47 4.09e-8 Neutrophil percentage of granulocytes;Eosinophil percentage of granulocytes; TGCT cis rs72634258 0.553 rs112697022 chr1:7949253 G/A cg26816564 chr1:7831052 VAMP3 0.61 4.61 0.38 9.72e-6 Inflammatory bowel disease; TGCT cis rs9359856 0.564 rs17506403 chr6:90499059 C/G cg13799429 chr6:90582589 CASP8AP2 -0.47 -4.58 -0.38 1.13e-5 Bipolar disorder; TGCT cis rs62209 0.800 rs11256938 chr10:11009060 A/G cg26901096 chr10:10994189 LOC254312 0.43 6.99 0.53 1.46e-10 Alzheimer's disease (late onset); TGCT cis rs3785574 0.650 rs7406102 chr17:62004749 G/A cg01411255 chr17:61851458 DDX42;CCDC47 -1.0 -11.19 -0.71 1.62e-20 Height; TGCT cis rs7914558 1.000 rs11191539 chr10:104819770 A/G cg05855489 chr10:104503620 C10orf26 0.51 4.48 0.37 1.67e-5 Schizophrenia;Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined); TGCT cis rs4563143 0.514 rs73029079 chr19:29294903 A/G cg14983838 chr19:29218262 NA 0.71 5.19 0.42 8.21e-7 Methadone dose in opioid dependence; TGCT cis rs1894292 0.527 rs4267705 chr4:74376081 T/C cg05868023 chr4:75230803 EREG -0.56 -5.05 -0.41 1.56e-6 Prostate cancer; TGCT cis rs7917772 0.582 rs4285804 chr10:104386309 T/A cg11453585 chr10:104263688 ACTR1A;SUFU -0.54 -5.58 -0.45 1.45e-7 Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour);White blood cell count;Waist-to-hip ratio adjusted for body mass index; TGCT cis rs68170813 0.559 rs7793594 chr7:106891829 C/T cg02696742 chr7:106810147 HBP1 -0.69 -5.61 -0.45 1.27e-7 Coronary artery disease; TGCT cis rs11785400 1.000 rs4484678 chr8:143730796 A/G cg24634471 chr8:143751801 JRK 0.54 5.85 0.46 4.19e-8 Schizophrenia; TGCT cis rs11098499 0.789 rs9991166 chr4:120237851 G/A cg09307838 chr4:120376055 NA 0.61 5.91 0.47 3.14e-8 Corneal astigmatism; TGCT cis rs9372498 0.536 rs62422227 chr6:118957200 C/G cg07617317 chr6:118971624 C6orf204 0.48 5.08 0.42 1.32e-6 Diastolic blood pressure; TGCT cis rs2658782 1.000 rs2658779 chr11:93163137 G/T cg18152523 chr11:93063302 CCDC67 0.67 5.46 0.44 2.47e-7 Pulmonary function decline; TGCT trans rs28595532 0.545 rs17516582 chr4:119296763 C/G cg26518628 chr1:97050305 NA -0.61 -7.34 -0.55 2.45e-11 Cannabis dependence symptom count; TGCT cis rs2562456 0.917 rs2650805 chr19:21687939 T/G cg25650185 chr19:21324782 ZNF431 0.61 5.38 0.43 3.6e-7 Pain; TGCT cis rs2440129 0.591 rs312466 chr17:6899221 G/A cg19536664 chr17:6899085 ALOX12 -0.37 -6.1 -0.48 1.26e-8 Tonsillectomy; TGCT cis rs7100689 0.646 rs1815650 chr10:82157464 C/T cg01528321 chr10:82214614 TSPAN14 0.73 7.73 0.57 3.25e-12 Post bronchodilator FEV1; TGCT cis rs13082711 0.558 rs1844983 chr3:27370203 C/T cg02860705 chr3:27208620 NA -0.29 -4.57 -0.38 1.15e-5 Systolic blood pressure;Diastolic blood pressure;Blood pressure; TGCT cis rs7043114 0.507 rs6479420 chr9:95116406 T/C cg14631576 chr9:95140430 CENPP -0.27 -4.45 -0.37 1.87e-5 Height; TGCT cis rs514406 0.627 rs485128 chr1:53344583 T/C cg27535305 chr1:53392650 SCP2 -0.28 -5.89 -0.47 3.35e-8 Monocyte count; TGCT cis rs1451375 1.000 rs1451375 chr7:50622712 A/C cg18232548 chr7:50535776 DDC -0.41 -6.53 -0.51 1.5e-9 Malaria; TGCT cis rs10504229 0.636 rs72649133 chr8:58054681 G/A cg08219700 chr8:58056026 NA 0.38 4.64 0.38 8.83e-6 Developmental language disorder (linguistic errors); TGCT cis rs1372520 0.684 rs2583978 chr4:90750326 A/C cg15133208 chr4:90757351 SNCA -0.5 -5.86 -0.47 4e-8 Neuroticism; TGCT cis rs9911578 0.967 rs6416932 chr17:57148991 G/A cg05425664 chr17:57184151 TRIM37 -0.68 -6.9 -0.53 2.4e-10 Intelligence (multi-trait analysis); TGCT cis rs2299587 0.573 rs6986123 chr8:17888073 G/A cg04898035 chr8:17640624 MTUS1 -0.22 -4.75 -0.39 5.54e-6 Economic and political preferences; TGCT cis rs75229567 0.618 rs77168443 chr12:70208563 G/A cg10114359 chr12:70132523 RAB3IP 1.35 6.68 0.51 7.19e-10 Triglyceride change in response to fenofibrate in statin-treated type 2 diabetes; TGCT cis rs7940866 0.740 rs7131121 chr11:130806424 A/G cg05962950 chr11:130786565 SNX19 0.67 6.75 0.52 5.05e-10 Schizophrenia; TGCT cis rs4820539 1.000 rs3827316 chr22:23468538 T/C cg21100191 chr22:23484243 RTDR1 0.88 10.0 0.67 1.28e-17 Bone mineral density;